id	category	name	description	provided_by	synonym	0000233	0000589	0100001	close_match	comment	consider	created_by	creation_date	default_namespace	deprecated	has_alternative_id	has_o_b_o_format_version	has_o_b_o_namespace	is_class_level	is_metadata_tag	knowledge_source	license	logical_interpretation	object	predicate	relation	shorthand	subject	type	version
GO:2000071	biolink:NamedThing	regulation of defense response by callose deposition	Any process that modulates the frequency, rate or extent of defense response by callose deposition.	tmpzr1t_l9r_go_relaxed.owl	regulation of callose localization during defense response|regulation of callose deposition during defense response							tb	2010-08-23T11:34:01Z					biological_process											owl:Class	
GO:0065007	biolink:NamedThing	biological regulation	Any process that modulates a measurable attribute of any biological process, quality or function.	tmpzr1t_l9r_go_relaxed.owl	regulation													biological_process											owl:Class	
GO:0070665	biolink:NamedThing	positive regulation of leukocyte proliferation	Any process that activates or increases the frequency, rate or extent of leukocyte proliferation.	tmpzr1t_l9r_go_relaxed.owl	activation of leukocyte proliferation|upregulation of leukocyte proliferation|stimulation of leukocyte proliferation|up-regulation of leukocyte proliferation|up regulation of leukocyte proliferation							mah	2009-05-28T05:36:46Z					biological_process											owl:Class	
GO:0070663	biolink:NamedThing	regulation of leukocyte proliferation	Any process that modulates the frequency, rate or extent of leukocyte proliferation.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-05-28T05:30:39Z					biological_process											owl:Class	
GO:0015537	biolink:NamedThing	xanthosine:proton symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: xanthosine(out) + H+(out) = xanthosine(in) + H+(in).	tmpzr1t_l9r_go_relaxed.owl	xanthosine:hydrogen ion symporter activity|xanthosine permease activity													molecular_function											owl:Class	
GO:0015506	biolink:NamedThing	nucleoside:proton symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: nucleoside(out) + H+(out) = nucleoside(in) + H+(in).	tmpzr1t_l9r_go_relaxed.owl	nucleoside:hydrogen symporter activity|nucleoside:hydrogen ion symporter activity|nucleoside permease activity											GO:0015536		molecular_function											owl:Class	
GO:0031585	biolink:NamedThing	regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity	Any process that modulates the frequency, rate or extent of the activity of the inositol 1,4,5-trisphosphate-sensitive calcium-release channel.	tmpzr1t_l9r_go_relaxed.owl	regulation of inositol-1,4,5-triphosphate receptor activity|regulation of IP3 receptor activity													biological_process											owl:Class	
GO:2001257	biolink:NamedThing	regulation of cation channel activity	Any process that modulates the frequency, rate or extent of cation channel activity.	tmpzr1t_l9r_go_relaxed.owl	regulation of cation diffusion facilitator activity|regulation of nonselective cation channel activity							vk	2011-12-07T07:14:43Z					biological_process											owl:Class	
GO:0034443	biolink:NamedThing	negative regulation of lipoprotein oxidation	Any process that stops, prevents, or reduces the frequency, rate or extent of lipoprotein oxidation.	tmpzr1t_l9r_go_relaxed.owl	inhibition of lipoprotein oxidation													biological_process											owl:Class	
GO:0050748	biolink:NamedThing	negative regulation of lipoprotein metabolic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving lipoproteins, any conjugated, water-soluble protein in which the nonprotein group consists of a lipid or lipids.	tmpzr1t_l9r_go_relaxed.owl	down regulation of lipoprotein metabolic process|inhibition of lipoprotein metabolic process|down-regulation of lipoprotein metabolic process|negative regulation of lipoprotein metabolism|downregulation of lipoprotein metabolic process													biological_process											owl:Class	
GO:0043395	biolink:NamedThing	heparan sulfate proteoglycan binding	Binding to a heparan sulfate proteoglycan, any proteoglycan containing heparan sulfate as the glycosaminoglycan carbohydrate unit.	tmpzr1t_l9r_go_relaxed.owl	heparin proteoglycan binding													molecular_function											owl:Class	
GO:1901681	biolink:NamedThing	sulfur compound binding	Binding to a sulfur compound.	tmpzr1t_l9r_go_relaxed.owl	sulfur molecular entity binding							pr	2012-11-26T20:45:23Z					molecular_function											owl:Class	
GO:0007523	biolink:NamedThing	larval visceral muscle development	The process whose specific outcome is the progression of the larval visceral muscle over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0048569	biolink:NamedThing	post-embryonic animal organ development	Development, taking place during the post-embryonic phase of an animal tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.	tmpzr1t_l9r_go_relaxed.owl	post-embryonic animal organogenesis													biological_process											owl:Class	
GO:0033021	biolink:NamedThing	cyclopentanol biosynthetic process	The chemical reactions and pathways resulting in the formation of cyclopentanol.	tmpzr1t_l9r_go_relaxed.owl	cyclopentanol synthesis|cyclopentanol biosynthesis|cyclopentanol anabolism|cyclopentanol formation													biological_process											owl:Class	
GO:0046165	biolink:NamedThing	alcohol biosynthetic process	The chemical reactions and pathways resulting in the formation of alcohols, any of a class of compounds containing one or more hydroxyl groups attached to a saturated carbon atom.	tmpzr1t_l9r_go_relaxed.owl	alcohol formation|alcohol synthesis|alcohol anabolism|alcohol biosynthesis													biological_process											owl:Class	
GO:0061291	biolink:NamedThing	canonical Wnt signaling pathway involved in ureteric bud branching	The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes that contributes to the branching of the ureteric bud. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes.	tmpzr1t_l9r_go_relaxed.owl	canonical Wnt receptor signalling pathway involved in ureteric bud branching|canonical Wnt receptor signaling pathway involved in ureteric bud branching							dph	2010-09-03T12:15:19Z					biological_process											owl:Class	
GO:0060070	biolink:NamedThing	canonical Wnt signaling pathway	The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes.	tmpzr1t_l9r_go_relaxed.owl	canonical Wnt receptor signaling pathway|canonical Wnt-activated signaling pathway|Wnt receptor signaling pathway through beta-catenin|Wnt receptor signalling pathway through beta-catenin|Wnt receptor signaling pathway via beta-catenin|frizzled-1 receptor signaling pathway													biological_process											owl:Class	
GO:1904525	biolink:NamedThing	positive regulation of DNA amplification	Any process that activates or increases the frequency, rate or extent of DNA amplification.	tmpzr1t_l9r_go_relaxed.owl	activation of DNA amplification|up regulation of DNA amplification|upregulation of DNA amplification|up-regulation of DNA amplification							mcc	2015-07-29T16:24:25Z					biological_process											owl:Class	
GO:1904523	biolink:NamedThing	regulation of DNA amplification	Any process that modulates the frequency, rate or extent of DNA amplification.	tmpzr1t_l9r_go_relaxed.owl								mcc	2015-07-29T16:24:13Z					biological_process											owl:Class	
GO:0033122	biolink:NamedThing	negative regulation of purine nucleotide catabolic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of purine nucleotides.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of purine nucleotide catabolism|negative regulation of purine nucleotide degradation|negative regulation of purine nucleotide breakdown													biological_process											owl:Class	
GO:0030812	biolink:NamedThing	negative regulation of nucleotide catabolic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of nucleotides.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of nucleotide catabolism|negative regulation of nucleotide degradation|down-regulation of nucleotide catabolic process|down regulation of nucleotide catabolic process|inhibition of nucleotide catabolic process|downregulation of nucleotide catabolic process|negative regulation of nucleotide breakdown													biological_process											owl:Class	
GO:0010147	biolink:NamedThing	fructan catabolic process	The chemical reactions and pathways resulting in the breakdown of fructan, a polysaccharide consisting of fructose residues.	tmpzr1t_l9r_go_relaxed.owl	levan catabolic process|fructan catabolism|levan catabolism|fructan breakdown|fructan degradation				MetaCyc:PWY-862									biological_process											owl:Class	
GO:0010145	biolink:NamedThing	fructan metabolic process	The chemical reactions and pathways involving fructan, a polysaccharide consisting of fructose residues.	tmpzr1t_l9r_go_relaxed.owl	fructan metabolism|levan metabolic process													biological_process											owl:Class	
GO:0010922	biolink:NamedThing	positive regulation of phosphatase activity	Any process that increases the rate or frequency of phosphatase activity. Phosphatases catalyze the hydrolysis of phosphoric monoesters, releasing inorganic phosphate.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0035306	biolink:NamedThing	positive regulation of dephosphorylation	Any process that activates or increases the frequency, rate or extent of removal of phosphate groups from a molecule.	tmpzr1t_l9r_go_relaxed.owl	stimulation of dephosphorylation|up regulation of dephosphorylation|upregulation of dephosphorylation|activation of dephosphorylation|up-regulation of dephosphorylation													biological_process											owl:Class	
GO:0016055	biolink:NamedThing	Wnt signaling pathway	The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell and ending with a change in cell state.	tmpzr1t_l9r_go_relaxed.owl	Wingless signaling pathway|Wg signalling pathway|Wnt-activated signaling pathway|frizzled signaling pathway|Wnt receptor signaling pathway|Wnt receptor signalling pathway|frizzled signalling pathway|Wg signaling pathway|Wingless signalling pathway											GO:0007222		biological_process											owl:Class	
GO:1905114	biolink:NamedThing	cell surface receptor signaling pathway involved in cell-cell signaling	Any cell surface receptor signaling pathway that is involved in cell-cell signaling.	tmpzr1t_l9r_go_relaxed.owl	cell surface receptor linked signaling pathway involved in cell-cell signalling|cell surface receptor linked signaling pathway involved in cell-cell signaling|cell surface receptor signaling pathway involved in cell-cell signalling|cell surface receptor linked signalling pathway involved in cell-cell signalling|cell surface receptor linked signalling pathway involved in cell-cell signaling|cell surface receptor linked signal transduction involved in cell-cell signalling|cell surface receptor linked signal transduction involved in cell-cell signaling							dos	2016-04-06T16:59:57Z					biological_process											owl:Class	
GO:0014058	biolink:NamedThing	negative regulation of acetylcholine secretion, neurotransmission	Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of acetylcholine.	tmpzr1t_l9r_go_relaxed.owl	inhibition of acetylcholine secretion|down regulation of acetylcholine secretion|down-regulation of acetylcholine secretion|downregulation of acetylcholine secretion													biological_process											owl:Class	
GO:0043271	biolink:NamedThing	negative regulation of ion transport	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	downregulation of ion transport|down regulation of ion transport|inhibition of ion transport|down-regulation of ion transport													biological_process											owl:Class	
GO:1900602	biolink:NamedThing	endocrocin biosynthetic process	The chemical reactions and pathways resulting in the formation of endocrocin.	tmpzr1t_l9r_go_relaxed.owl	endocrocin formation|endocrocin anabolism|endocrocin biosynthesis|endocrocin synthesis							di	2012-05-15T06:57:42Z					biological_process											owl:Class	
GO:1900600	biolink:NamedThing	endocrocin metabolic process	The chemical reactions and pathways involving endocrocin.	tmpzr1t_l9r_go_relaxed.owl	endocrocin metabolism							di	2012-05-15T06:57:14Z					biological_process											owl:Class	
GO:0070292	biolink:NamedThing	N-acylphosphatidylethanolamine metabolic process	The chemical reactions and pathways involving N-acylphosphatidylethanolamines. An N-acylphosphatidylethanolamine is a phosphatidylethanolamine substituted at nitrogen by an acyl group.	tmpzr1t_l9r_go_relaxed.owl	N-acylphosphatidylethanolamine metabolism|NAPE metabolism|NAPE metabolic process													biological_process											owl:Class	
GO:1901564	biolink:NamedThing	organonitrogen compound metabolic process	The chemical reactions and pathways involving organonitrogen compound.	tmpzr1t_l9r_go_relaxed.owl	organonitrogen compound metabolism							pr	2012-11-04T15:17:52Z					biological_process											owl:Class	
GO:1990661	biolink:NamedThing	S100A8 complex	A protein complex composed of a S100A8 dimer and capable of binding to toll-like receptor 4 (TLR4).	tmpzr1t_l9r_go_relaxed.owl	S100A8 homodimer					An example of this is S100A8 in human (UniProt symbol P27005) in PMID:25417112 (inferred from direct assay).		bhm	2015-02-25T15:33:32Z					cellular_component											owl:Class	
GO:0032991	biolink:NamedThing	protein-containing complex	A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.	tmpzr1t_l9r_go_relaxed.owl	protein containing complex|macromolecule complex|protein complex|macromolecular complex|protein-protein complex					A protein complex in this context is meant as a stable set of interacting proteins which can be co-purified by an acceptable method, and where the complex has been shown to exist as an isolated, functional unit in vivo. Acceptable experimental methods include stringent protein purification followed by detection of protein interaction. The following methods should be considered non-acceptable: simple immunoprecipitation, pull-down experiments from cell extracts without further purification, colocalization and 2-hybrid screening. Interactions that should not be captured as protein complexes include: 1) enzyme/substrate, receptor/ligand or any similar transient interactions, unless these are a critical part of the complex assembly or are required e.g. for the receptor to be functional; 2) proteins associated in a pull-down/co-immunoprecipitation assay with no functional link or any evidence that this is a defined biological entity rather than a loose-affinity complex; 3) any complex where the only evidence is based on genetic interaction data; 4) partial complexes, where some subunits (e.g. transmembrane ones) cannot be expressed as recombinant proteins and are excluded from experiments (in this case, independent evidence is necessary to find out the composition of the full complex, if known). Interactions that may be captured as protein complexes include: 1) enzyme/substrate or receptor/ligand if the complex can only assemble and become functional in the presence of both classes of subunits; 2) complexes where one of the members has not been shown to be physically linked to the other(s), but is a homologue of, and has the same functionality as, a protein that has been experimentally demonstrated to form a complex with the other member(s); 3) complexes whose existence is accepted based on localization and pharmacological studies, but for which experimental evidence is not yet available for the complex as a whole.						GO:0043234		cellular_component											owl:Class	
GO:0019543	biolink:NamedThing	propionate catabolic process	The chemical reactions and pathways resulting in the breakdown of propionate, the anion derived from propionic acid.	tmpzr1t_l9r_go_relaxed.owl	propionate degradation|propionate breakdown|propionate catabolism													biological_process											owl:Class	
GO:0019541	biolink:NamedThing	propionate metabolic process	The chemical reactions and pathways involving propionate, the anion derived from propionic (propanoic) acid, a carboxylic acid important in the energy metabolism of ruminants.	tmpzr1t_l9r_go_relaxed.owl	propanoate metabolic process|propionate metabolism|propanoate metabolism													biological_process											owl:Class	
GO:0051007	biolink:NamedThing	squalene-hopene cyclase activity	Catalysis of the reaction: squalene = hop-22(29)-ene.	tmpzr1t_l9r_go_relaxed.owl	squalene mutase (cyclizing)|squalene:hopene cyclase activity				MetaCyc:5.4.99.17-RXN|RHEA:17637|EC:5.4.99.17									molecular_function											owl:Class	
GO:0034072	biolink:NamedThing	squalene cyclase activity	Catalysis of the reaction: squalene = triterpene.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0051129	biolink:NamedThing	negative regulation of cellular component organization	Any process that stops, prevents, or reduces the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.	tmpzr1t_l9r_go_relaxed.owl	inhibition of cell organization|negative regulation of cellular component organization and biogenesis|downregulation of cell organization|down regulation of cell organization|down-regulation of cell organization|negative regulation of cell organisation													biological_process											owl:Class	
GO:0051479	biolink:NamedThing	mannosylglycerate biosynthetic process	The chemical reactions and pathways resulting in the formation of mannosylglycerate, a very common compatible solute in thermophilic and hyperthermophilic organisms.	tmpzr1t_l9r_go_relaxed.owl	mannosylglycerate synthesis|mannosylglycerate biosynthesis|mannosylglycerate formation|mannosylglycerate anabolism													biological_process											owl:Class	
GO:0016138	biolink:NamedThing	glycoside biosynthetic process	The chemical reactions and pathways resulting in the formation of glycosides, compounds in which a glycosyl group is substituted into a hydroxyl, thiol or selenol group in another compound.	tmpzr1t_l9r_go_relaxed.owl	O-glycoside anabolism|O-glycoside synthesis|glycoside anabolism|glycoside formation|O-glycoside formation|glycoside biosynthesis|O-glycoside biosynthesis|glycoside synthesis|O-glycoside biosynthetic process											GO:0016141		biological_process											owl:Class	
GO:0052783	biolink:NamedThing	reuteran metabolic process	The chemical reactions and pathways involving reuteran, a soluble glucan polymer with mainly alpha-(1->4) glycosidic linkages and significant amounts of alpha-(1->6) and alpha-(1->4,6) glucosidic linkages.	tmpzr1t_l9r_go_relaxed.owl								ai	2011-10-04T09:16:35Z					biological_process											owl:Class	
GO:0030978	biolink:NamedThing	alpha-glucan metabolic process	The chemical reactions and pathways involving alpha-glucans, compounds composed of glucose residues linked by alpha-D-glucosidic bonds.	tmpzr1t_l9r_go_relaxed.owl	alpha-glucan metabolism													biological_process											owl:Class	
GO:0035038	biolink:NamedThing	female pronucleus assembly	Assembly of the haploid nucleus of the unfertilized egg.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0070925	biolink:NamedThing	organelle assembly	The aggregation, arrangement and bonding together of a set of components to form an organelle. An organelle is an organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-09-15T03:00:51Z					biological_process											owl:Class	
GO:0018705	biolink:NamedThing	1,2-dichloroethene reductive dehalogenase activity	Catalysis of the reaction: 1,2-dichloroethene + 2 H+ + 2 e- = HCl + vinyl chloride.	tmpzr1t_l9r_go_relaxed.owl	1,2-dichloroethylene reductive dehalogenase activity				UM-BBD_enzymeID:e0272									molecular_function											owl:Class	
GO:0016491	biolink:NamedThing	oxidoreductase activity	Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.	tmpzr1t_l9r_go_relaxed.owl	oxidoreductase activity, acting on other substrates|redox activity				Reactome:R-HSA-9026917|Reactome:R-HSA-8878581|Reactome:R-HSA-9024624|Reactome:R-HSA-9026001|Reactome:R-HSA-209921|Reactome:R-HSA-8936442|Reactome:R-HSA-1614362|Reactome:R-HSA-9027033|Reactome:R-HSA-9693722|Reactome:R-HSA-5662660|Reactome:R-HSA-9025007|EC:1.-.-.-|Reactome:R-HSA-390425|Reactome:R-HSA-3095889|Reactome:R-HSA-9024630|Reactome:R-HSA-209960|Reactome:R-HSA-9020249|Reactome:R-HSA-390438|Reactome:R-HSA-9020260									molecular_function											owl:Class	
GO:0002175	biolink:NamedThing	protein localization to paranode region of axon	A cellular protein localization process in which a protein is transported to, or maintained at, the paranode region of an axon.	tmpzr1t_l9r_go_relaxed.owl	protein localisation to paranode region of axon							hjd	2010-11-15T10:28:20Z					biological_process											owl:Class	
GO:0034613	biolink:NamedThing	cellular protein localization	Any process in which a protein is transported to, and/or maintained in, a specific location at the level of a cell. Localization at the cellular level encompasses movement within the cell, from within the cell to the cell surface, or from one location to another at the surface of a cell.	tmpzr1t_l9r_go_relaxed.owl	channel localizer activity|cellular protein localisation											GO:0016249		biological_process											owl:Class	
GO:0000107	biolink:NamedThing	imidazoleglycerol-phosphate synthase activity	Catalysis of the reaction: phosphoribulosylformimino-AICAR-P + L-glutamine = D-erythro-imidazole-glycerol-phosphate + aminoimidazole carboxamide ribonucleotide + L-glutamate + 2 H(+).	tmpzr1t_l9r_go_relaxed.owl	imidazole-glycerol-phosphate synthase activity|glutamine amidotransferase:cyclase activity|imidazole glycerol phosphate synthase activity|imidazoleglycerol phosphate synthase activity				RHEA:24793|MetaCyc:GLUTAMIDOTRANS-RXN									molecular_function											owl:Class	
GO:0016763	biolink:NamedThing	pentosyltransferase activity	Catalysis of the transfer of a pentosyl group from one compound (donor) to another (acceptor).	tmpzr1t_l9r_go_relaxed.owl	transferase activity, transferring pentosyl groups	https://github.com/geneontology/go-ontology/issues/20486			EC:2.4.2.-|Reactome:R-HSA-112266|Reactome:R-HSA-112265									molecular_function											owl:Class	
GO:0097666	biolink:NamedThing	SCF-Met30/Pof1 ubiquitin ligase complex	An SCF ubiquitin ligase complex in which the F-box protein is Met30 in S. cerevisiae (Pof1 in S pombe).	tmpzr1t_l9r_go_relaxed.owl								pr	2014-10-06T10:27:49Z					cellular_component											owl:Class	
GO:0019005	biolink:NamedThing	SCF ubiquitin ligase complex	A ubiquitin ligase complex in which a cullin from the Cul1 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by a Skp1 adaptor and an F-box protein. SCF complexes are involved in targeting proteins for degradation by the proteasome. The best characterized complexes are those from yeast and mammals (with core subunits named Cdc53/Cul1, Rbx1/Hrt1/Roc1).	tmpzr1t_l9r_go_relaxed.owl	SCF complex substrate recognition subunit|Skp1/Cul1/F-box protein complex|SCF complex|CRL1 complex|CDL1 complex|Cul1-RING ubiquitin ligase complex|cullin-RING ligase 1				Wikipedia:SCF_complex									cellular_component											owl:Class	
GO:2001037	biolink:NamedThing	positive regulation of tongue muscle cell differentiation	Any process that activates or increases the frequency, rate or extent of tongue muscle cell differentiation.	tmpzr1t_l9r_go_relaxed.owl								yaf	2011-08-24T11:10:22Z					biological_process											owl:Class	
GO:0046330	biolink:NamedThing	positive regulation of JNK cascade	Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the JNK cascade.	tmpzr1t_l9r_go_relaxed.owl	stimulation of JNK cascade|upregulation of JNK cascade|up regulation of JNK cascade|activation of JNK cascade|up-regulation of JNK cascade													biological_process											owl:Class	
GO:0072235	biolink:NamedThing	metanephric distal tubule development	The process whose specific outcome is the progression of the metanephric distal tubule over time, from its formation to the mature structure. The metanephric distal tubule is a metanephric nephron tubule that begins at the metanephric macula densa and extends to the metanephric connecting tubule.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-03-18T03:45:37Z					biological_process											owl:Class	
GO:0072234	biolink:NamedThing	metanephric nephron tubule development	The progression of a metanephric nephron tubule over time, from its initial formation to the mature structure. A metanephric nephron tubule is an epithelial tube that is part of the metanephric nephron, the functional part of the metanephros.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-03-18T03:41:23Z					biological_process											owl:Class	
GO:0097673	biolink:NamedThing	SCF-Ucc1 ubiquitin ligase complex	An SCF ubiquitin ligase complex in which the F-box protein is YLR224W in S. cerevisiae.	tmpzr1t_l9r_go_relaxed.owl	SCF-YLR224W ubiquitin ligase complex							pr	2014-10-06T10:30:31Z					cellular_component											owl:Class	
GO:1903242	biolink:NamedThing	regulation of cardiac muscle hypertrophy in response to stress	Any process that modulates the frequency, rate or extent of cardiac muscle hypertrophy in response to stress.	tmpzr1t_l9r_go_relaxed.owl								rl	2014-08-01T16:31:36Z					biological_process											owl:Class	
GO:0010611	biolink:NamedThing	regulation of cardiac muscle hypertrophy	Any process that modulates the rate, frequency or extent of the enlargement or overgrowth of all or part of the heart due to an increase in size (not length) of individual cardiac muscle fibers, without cell division.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0140407	biolink:NamedThing	L-alanine:proton antiporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + L-alanine(in) = H+(in) + L-alanine(out).	tmpzr1t_l9r_go_relaxed.owl								pg	2019-12-11T14:17:48Z					molecular_function											owl:Class	
GO:0015180	biolink:NamedThing	L-alanine transmembrane transporter activity	Enables the transfer of L-alanine from one side of a membrane to the other. L-alanine is the L-enantiomer of 2-aminopropanoic acid.	tmpzr1t_l9r_go_relaxed.owl	L-alanine transporter activity													molecular_function											owl:Class	
GO:1902634	biolink:NamedThing	1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process	The chemical reactions and pathways resulting in the breakdown of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate.	tmpzr1t_l9r_go_relaxed.owl	1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate breakdown|1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolism|1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate degradation					Phosphatidylinositol-4,5-bisphosphate, PtdIns(4,5)P(2) common name.		di	2014-01-18T00:34:36Z					biological_process											owl:Class	
GO:0031161	biolink:NamedThing	phosphatidylinositol catabolic process	The chemical reactions and pathways resulting in the breakdown of phosphatidylinositol, any glycophospholipid with its sn-glycerol 3-phosphate residue is esterified to the 1-hydroxyl group of 1D-myo-inositol.	tmpzr1t_l9r_go_relaxed.owl	PtdIns catabolic process|phosphatidylinositol breakdown|PtdIns catabolism|phosphatidylinositol degradation|phosphatidylinositol catabolism													biological_process											owl:Class	
GO:0002452	biolink:NamedThing	B cell receptor editing	The process of replacing receptors on B cells, in which RAG gene expression allows continued light-chain gene rearrangement and expression of a new light change which combines with the previous heavy chain to form a new receptor.	tmpzr1t_l9r_go_relaxed.owl	B-lymphocyte receptor editing|B lymphocyte receptor editing|B-cell receptor editing													biological_process											owl:Class	
GO:0016447	biolink:NamedThing	somatic recombination of immunoglobulin gene segments	The process in which immunoglobulin genes are formed through recombination of the germline genetic elements, as known as immunoglobulin gene segments, within a single locus.	tmpzr1t_l9r_go_relaxed.owl	somatic recombination of antibody gene segments													biological_process											owl:Class	
GO:0106003	biolink:NamedThing	amyloid-beta complex	Protein complex involved in modulation of signaling and synaptic function in the brain, predominantly in the cerebral cortex and hippocampus. Forms dimers and multimers of amyloid beta peptide 40 and peptide 42 (proteolytic cleavage products of amyloid beta A4 protein, also known as amyloid beta precursor protein). Mostly found in the extracellular space with a proportion occurring as membrane-bound species. Influences synaptic plasticity through various receptors, mediates dendritic spine loss leading to decreased synapse density, inhibits long-term potentiation (LTP) and enhances long-term depression (LTD). Soluble multimeric form is the main pathogenic species linked to Alzheimer's disease.	tmpzr1t_l9r_go_relaxed.owl	amyloid-beta protein 40/42 complex|amyloid-beta protein 42 complex|beta-amyloid complex|heterodimer of amyloid beta protein|amyloid beta trimer|ADDL complex|betaA complex|heterotrimer of amyloid beta protein|amyloid beta heterodimer|amyloid-beta protein 40 complex|amyloid beta heterooligomer|homodimer of amyloid beta protein|amyloid beta oligomer|beta amyloid complex|amyloid beta heterotrimer|amyloid beta dimer|Abeta-derived diffusible ligand complex|amyloid beta homooligomer|homotrimer of amyloid beta protein|Abeta complex|amyloid beta homotrimer|heterooligomer of amyloid beta protein|amyloid beta homodimer|homooligomer of amyloid beta protein|amyloid beta complex					An example is Protein 40 of APP (P05067-PRO_0000000093) in PMID:18568035 (inferred by direct assay).		hjd	2017-03-15T19:19:29Z					cellular_component											owl:Class	
GO:0140057	biolink:NamedThing	vacuole-mitochondria membrane tethering	The attachment of a mitochondrial membrane to a vacuolar membrane via molecular tethers that physically bridge their respective membranes and attach them to each other. The tethering may facilitate exchange of metabolites between the organelles.	tmpzr1t_l9r_go_relaxed.owl								pg	2017-06-27T10:31:12Z					biological_process											owl:Class	
GO:0140056	biolink:NamedThing	organelle localization by membrane tethering	The process by which an organelle membrane interacts with another membrane via molecular tethers that physically bridge the two membranes and attach them to each other.	tmpzr1t_l9r_go_relaxed.owl								pg	2017-06-27T09:58:51Z					biological_process											owl:Class	
GO:1904051	biolink:NamedThing	regulation of protein targeting to vacuole involved in autophagy	Any process that modulates the frequency, rate or extent of protein targeting to vacuole involved in autophagy.	tmpzr1t_l9r_go_relaxed.owl						An example of this is SMURF1 in human (UniProt symbol Q9HCE7) in PMID:22020285 (inferred from mutant phenotype).		pad	2015-03-17T13:54:16Z					biological_process											owl:Class	
GO:0051998	biolink:NamedThing	protein carboxyl O-methyltransferase activity	Catalysis of the transfer of a methyl group to a carboxyl group on a protein.	tmpzr1t_l9r_go_relaxed.owl	protein carboxyl methyltransferase activity							ai	2010-07-20T09:23:00Z					molecular_function											owl:Class	
GO:0008276	biolink:NamedThing	protein methyltransferase activity	Catalysis of the transfer of a methyl group (CH3-) to a protein.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-9632182									molecular_function											owl:Class	
GO:0005916	biolink:NamedThing	fascia adherens	A cell-cell junction that contains the transmembrane protein N-cadherin, which interacts with identical molecules from neighbouring cells to form a tight mechanical intercellular link; forms a large portion of the intercalated disc, the structure at which myofibrils terminate in cardiomyocytes.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Fascia_adherens									cellular_component											owl:Class	
GO:0005911	biolink:NamedThing	cell-cell junction	A cell junction that forms a connection between two or more cells of an organism; excludes direct cytoplasmic intercellular bridges, such as ring canals in insects.	tmpzr1t_l9r_go_relaxed.owl	cell-cell contact region|cell-cell contact zone|intercellular junction	https://github.com/geneontology/go-ontology/issues/22122			NIF_Subcellular:sao1922892319									cellular_component											owl:Class	
GO:0102249	biolink:NamedThing	phosphatidylcholine:diacylglycerol cholinephosphotransferase activity	Catalysis of the reaction: a phosphatidylcholine + a 1,2-diacyl-sn-glycerol = a 1,2-diacyl-sn-glycerol + a phosphatidylcholine.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-12386									molecular_function											owl:Class	
GO:0016780	biolink:NamedThing	phosphotransferase activity, for other substituted phosphate groups	Catalysis of the transfer of a substituted phosphate group, other than diphosphate or nucleotidyl residues, from one compound (donor) to a another (acceptor).	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-163069|Reactome:R-HSA-162742|EC:2.7.8.-									molecular_function											owl:Class	
GO:1900590	biolink:NamedThing	violaceol I biosynthetic process	The chemical reactions and pathways resulting in the formation of violaceol I.	tmpzr1t_l9r_go_relaxed.owl	violaceol I anabolism|violaceol I formation|violaceol I biosynthesis|violaceol I synthesis							di	2012-05-15T06:51:16Z					biological_process											owl:Class	
GO:1901503	biolink:NamedThing	ether biosynthetic process	The chemical reactions and pathways resulting in the formation of ether.	tmpzr1t_l9r_go_relaxed.owl	ether synthesis|ether formation|ether biosynthesis|ether anabolism							pr	2012-10-17T09:42:47Z					biological_process											owl:Class	
GO:0006684	biolink:NamedThing	sphingomyelin metabolic process	The chemical reactions and pathways involving sphingomyelin, N-acyl-4-sphingenyl-1-O-phosphorylcholine, any of a class of phospholipids in which the amino group of sphingosine is in amide linkage with one of several fatty acids, while the terminal hydroxyl group of sphingosine is esterified to phosphorylcholine.	tmpzr1t_l9r_go_relaxed.owl	sphingomyelin metabolism													biological_process											owl:Class	
GO:0006665	biolink:NamedThing	sphingolipid metabolic process	The chemical reactions and pathways involving sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid).	tmpzr1t_l9r_go_relaxed.owl	sphingolipid metabolism													biological_process											owl:Class	
GO:0006414	biolink:NamedThing	translational elongation	The successive addition of amino acid residues to a nascent polypeptide chain during protein biosynthesis.	tmpzr1t_l9r_go_relaxed.owl	translation elongation|protein synthesis elongation											GO:0006442|GO:0006455		biological_process											owl:Class	
GO:0034645	biolink:NamedThing	cellular macromolecule biosynthetic process	The chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, carried out by individual cells.	tmpzr1t_l9r_go_relaxed.owl	cellular macromolecule biosynthesis|cellular biopolymer biosynthetic process|cellular macromolecule formation|cellular macromolecule synthesis|cellular macromolecule anabolism											GO:0034961		biological_process											owl:Class	
GO:0006208	biolink:NamedThing	pyrimidine nucleobase catabolic process	The chemical reactions and pathways resulting in the breakdown of pyrimidine nucleobases, 1,3-diazine, organic nitrogenous bases.	tmpzr1t_l9r_go_relaxed.owl	pyrimidine base catabolism|pyrimidine base breakdown|pyrimidine base degradation|pyrimidine base catabolic process													biological_process											owl:Class	
GO:0006206	biolink:NamedThing	pyrimidine nucleobase metabolic process	The chemical reactions and pathways involving pyrimidine nucleobases, 1,3-diazine, organic nitrogenous bases.	tmpzr1t_l9r_go_relaxed.owl	pyrimidine metabolic process|pyrimidine base metabolism|pyrimidine base metabolic process|pyrimidine metabolism													biological_process											owl:Class	
GO:1902081	biolink:NamedThing	negative regulation of calcium ion import into sarcoplasmic reticulum	Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion import into sarcoplasmic reticulum.	tmpzr1t_l9r_go_relaxed.owl	inhibition of calcium ion import into sarcoplasmic reticulum|downregulation of calcium ion import into sarcoplasmic reticulum|down-regulation of calcium ion import into sarcoplasmic reticulum|down regulation of calcium ion import into sarcoplasmic reticulum							rl	2013-04-24T16:07:59Z					biological_process											owl:Class	
GO:0090281	biolink:NamedThing	negative regulation of calcium ion import	Any process that decreases the rate, frequency, or extent of the directed movement of calcium ions into a cell or organelle.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of transmembrane calcium influx							tb	2010-02-08T05:11:20Z					biological_process											owl:Class	
GO:1900551	biolink:NamedThing	N',N'',N'''-triacetylfusarinine C biosynthetic process	The chemical reactions and pathways resulting in the formation of N',N'',N'''-triacetylfusarinine C.	tmpzr1t_l9r_go_relaxed.owl	N',N'',N'''-triacetylfusarinine C synthesis|N',N'',N'''-triacetylfusarinine C formation|N',N'',N'''-triacetylfusarinine C biosynthesis|N',N'',N'''-triacetylfusarinine C anabolism							di	2012-05-15T01:00:58Z					biological_process											owl:Class	
GO:1901566	biolink:NamedThing	organonitrogen compound biosynthetic process	The chemical reactions and pathways resulting in the formation of organonitrogen compound.	tmpzr1t_l9r_go_relaxed.owl	organonitrogen compound anabolism|organonitrogen compound formation|organonitrogen compound biosynthesis|organonitrogen compound synthesis							pr	2012-11-04T15:18:00Z					biological_process											owl:Class	
GO:0032076	biolink:NamedThing	negative regulation of deoxyribonuclease activity	Any process that stops or reduces the rate of deoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid.	tmpzr1t_l9r_go_relaxed.owl	inhibition of deoxyribonuclease activity|down regulation of deoxyribonuclease activity|deoxyribonuclease inhibitor|down-regulation of deoxyribonuclease activity|downregulation of deoxyribonuclease activity|DNase inhibitor													biological_process											owl:Class	
GO:0032070	biolink:NamedThing	regulation of deoxyribonuclease activity	Any process that modulates the frequency, rate or extent of deoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid.	tmpzr1t_l9r_go_relaxed.owl	deoxyribonuclease regulator|DNase regulator													biological_process											owl:Class	
GO:0001964	biolink:NamedThing	startle response	An action or movement due to the application of a sudden unexpected stimulus.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Startle_reaction									biological_process											owl:Class	
GO:0009605	biolink:NamedThing	response to external stimulus	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to environmental stimulus					Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.								biological_process											owl:Class	
GO:0046611	biolink:NamedThing	lysosomal proton-transporting V-type ATPase complex	A proton-transporting two-sector ATPase complex found in the lysosomal membrane, where it acts as a proton pump to mediate acidification of the lysosomal lumen.	tmpzr1t_l9r_go_relaxed.owl	lysosomal membrane hydrogen-transporting ATPase|lysosomal hydrogen-translocating V-type ATPase complex													cellular_component											owl:Class	
GO:0016471	biolink:NamedThing	vacuolar proton-transporting V-type ATPase complex	A proton-transporting two-sector ATPase complex found in the vacuolar membrane, where it acts as a proton pump to mediate acidification of the vacuolar lumen.	tmpzr1t_l9r_go_relaxed.owl	vacuolar hydrogen-translocating V-type ATPase complex					See also the cellular component terms 'vacuolar proton-transporting V-type ATPase, V1 domain ; GO:0000221' and 'vacuolar proton-transporting V-type ATPase, V0 domain ; GO:0000220' and the molecular function term 'hydrogen ion transporting ATPase activity, rotational mechanism ; GO:0046961'.								cellular_component											owl:Class	
GO:1901672	biolink:NamedThing	positive regulation of systemic acquired resistance	Any process that activates or increases the frequency, rate or extent of systemic acquired resistance.	tmpzr1t_l9r_go_relaxed.owl	activation of systemic acquired resistance|upregulation of systemic acquired resistance|positive regulation of salicylic acid-dependent systemic resistance|upregulation of salicylic acid-dependent systemic resistance|up regulation of systemic acquired resistance|up-regulation of salicylic acid-dependent systemic resistance|up-regulation of systemic acquired resistance|up regulation of salicylic acid-dependent systemic resistance|activation of salicylic acid-dependent systemic resistance							tb	2012-11-21T22:03:58Z					biological_process											owl:Class	
GO:0032103	biolink:NamedThing	positive regulation of response to external stimulus	Any process that activates, maintains or increases the rate of a response to an external stimulus.	tmpzr1t_l9r_go_relaxed.owl	up regulation of response to external stimulus|activation of response to external stimulus|up-regulation of response to external stimulus|stimulation of response to external stimulus|upregulation of response to external stimulus					Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.								biological_process											owl:Class	
GO:0060981	biolink:NamedThing	cell migration involved in coronary angiogenesis	The orderly movement of a cell from one site to another that will contribute to the formation of new blood vessels in the heart from pre-existing blood vessels.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-10-06T02:49:12Z					biological_process											owl:Class	
GO:0060973	biolink:NamedThing	cell migration involved in heart development	The orderly movement of a cell from one site to another that will contribute to the progression of the heart over time, from its initial formation, to the mature organ.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-10-06T10:53:49Z					biological_process											owl:Class	
GO:0071359	biolink:NamedThing	cellular response to dsRNA	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a double-stranded RNA stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to double-stranded RNA							mah	2009-12-11T03:00:32Z					biological_process											owl:Class	
GO:0071407	biolink:NamedThing	cellular response to organic cyclic compound	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic cyclic compound stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to organic cyclic substance							mah	2009-12-14T02:55:58Z					biological_process											owl:Class	
GO:0008523	biolink:NamedThing	sodium-dependent multivitamin transmembrane transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: multivitamin(out) + Na+(out) = multivitamin(in) + Na+(in). Multivitamins include pantothenate, biotin and lipoate.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-199219|Reactome:R-HSA-429581|Reactome:R-HSA-199206									molecular_function											owl:Class	
GO:0090482	biolink:NamedThing	vitamin transmembrane transporter activity	Enables the transfer of a vitamin from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	vitamin transporter activity|vitamin or cofactor transporter activity							tb	2012-10-02T16:50:50Z			GO:0051183		molecular_function											owl:Class	
GO:0030758	biolink:NamedThing	3,7-dimethylquercitin 4'-O-methyltransferase activity	Catalysis of the reaction: 3',4',5-trihydroxy-3,7-dimethoxyflavone + S-adenosyl-L-methionine(1+) = 3',5-dihydroxy-3,4',7-trimethoxyflavone + S-adenosyl-L-homocysteine + H(+).	tmpzr1t_l9r_go_relaxed.owl	S-adenosyl-L-methionine:3',4',5-trihydroxy-3,7-dimethoxyflavone 4'-O-methyltransferase activity|S-adenosyl-L-methionine:5,3',4'-trihydroxy-3,7-dimethoxyflavone 4'-O-methyltransferase activity|3,7-dimethylquercetin 4'-O-methyltransferase activity|flavonol 4'-methyltransferase activity|flavonol 4'-O-methyltransferase activity|4'-OMT activity				RHEA:21832|KEGG_REACTION:R03456|MetaCyc:2.1.1.83-RXN|EC:2.1.1.83									molecular_function											owl:Class	
GO:0008757	biolink:NamedThing	S-adenosylmethionine-dependent methyltransferase activity	Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a substrate.	tmpzr1t_l9r_go_relaxed.owl	S-adenosyl methionine-dependent methyltransferase activity|SAM-dependent methyltransferase activity													molecular_function											owl:Class	
GO:0098005	biolink:NamedThing	viral head-tail joining	Process by which virus heads and tails are attached to each other.	tmpzr1t_l9r_go_relaxed.owl	virus head-tail joining|phage head tail joining							bm	2012-07-18T16:11:59Z					biological_process											owl:Class	
GO:0016032	biolink:NamedThing	viral process	A multi-organism process in which a virus is a participant. The other participant is the host. Includes infection of a host cell, replication of the viral genome, and assembly of progeny virus particles. In some cases the viral genetic material may integrate into the host genome and only subsequently, under particular circumstances, 'complete' its life cycle.	tmpzr1t_l9r_go_relaxed.owl	virus process|virulence|viral infection				Wikipedia:Viral_life_cycle	See also the biological process terms 'viral infectious cycle ; GO:0019058' and 'lysogeny ; GO:0030069'.						GO:0022415		biological_process											owl:Class	
GO:0008103	biolink:NamedThing	oocyte microtubule cytoskeleton polarization	Establishment and maintenance of a specific axis of polarity of the oocyte microtubule network. The axis is set so that the minus and plus ends of the microtubules of the mid stage oocyte are positioned along the anterior cortex and at the posterior pole, respectively. An example of this is found in Drosophila melanogaster.	tmpzr1t_l9r_go_relaxed.owl												GO:0048129		biological_process											owl:Class	
GO:0007017	biolink:NamedThing	microtubule-based process	Any cellular process that depends upon or alters the microtubule cytoskeleton, that part of the cytoskeleton comprising microtubules and their associated proteins.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0031692	biolink:NamedThing	alpha-1B adrenergic receptor binding	Binding to an alpha-1B adrenergic receptor.	tmpzr1t_l9r_go_relaxed.owl	alpha-1B adrenergic receptor ligand													molecular_function											owl:Class	
GO:0031690	biolink:NamedThing	adrenergic receptor binding	Binding to an adrenergic receptor.	tmpzr1t_l9r_go_relaxed.owl	adrenergic receptor ligand													molecular_function											owl:Class	
GO:0033343	biolink:NamedThing	positive regulation of collagen binding	Any process that activates or increases the frequency, rate or extent of collagen binding.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of collagen binding|activation of collagen binding|upregulation of collagen binding|stimulation of collagen binding|up regulation of collagen binding													biological_process											owl:Class	
GO:0033341	biolink:NamedThing	regulation of collagen binding	Any process that modulates the frequency, rate or extent of collagen binding.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1900815	biolink:NamedThing	monodictyphenone biosynthetic process	The chemical reactions and pathways resulting in the formation of monodictyphenone.	tmpzr1t_l9r_go_relaxed.owl	monodictyphenone synthesis|monodictyphenone formation|monodictyphenone anabolism|monodictyphenone biosynthesis							di	2012-06-04T10:11:35Z					biological_process											owl:Class	
GO:0016053	biolink:NamedThing	organic acid biosynthetic process	The chemical reactions and pathways resulting in the formation of organic acids, any acidic compound containing carbon in covalent linkage.	tmpzr1t_l9r_go_relaxed.owl	organic acid synthesis|organic acid biosynthesis|organic acid anabolism|organic acid formation													biological_process											owl:Class	
GO:1901173	biolink:NamedThing	phytoene catabolic process	The chemical reactions and pathways resulting in the breakdown of phytoene.	tmpzr1t_l9r_go_relaxed.owl	phytoene catabolism|phytoene breakdown|phytoene degradation							yaf	2012-07-19T09:48:07Z					biological_process											owl:Class	
GO:1901172	biolink:NamedThing	phytoene metabolic process	The chemical reactions and pathways involving phytoene.	tmpzr1t_l9r_go_relaxed.owl	phytoene metabolism							yaf	2012-07-19T09:47:46Z					biological_process											owl:Class	
GO:2000863	biolink:NamedThing	positive regulation of estrogen secretion	Any process that activates or increases the frequency, rate or extent of estrogen secretion.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of oestrogen secretion							bf	2011-07-26T08:48:31Z					biological_process											owl:Class	
GO:2000861	biolink:NamedThing	regulation of estrogen secretion	Any process that modulates the frequency, rate or extent of estrogen secretion.	tmpzr1t_l9r_go_relaxed.owl	regulation of oestrogen secretion							bf	2011-07-26T08:48:24Z					biological_process											owl:Class	
GO:0045115	biolink:NamedThing	regulation of beta 2 integrin biosynthetic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of beta 2 integrins.	tmpzr1t_l9r_go_relaxed.owl	regulation of beta 2 integrin synthesis|regulation of beta 2 integrin anabolism|regulation of beta 2 integrin biosynthesis|regulation of beta 2 integrin formation													biological_process											owl:Class	
GO:0008187	biolink:NamedThing	poly-pyrimidine tract binding	Binding to a stretch of pyrimidines (cytosine or uracil) in an RNA molecule.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0003727	biolink:NamedThing	single-stranded RNA binding	Binding to single-stranded RNA.	tmpzr1t_l9r_go_relaxed.owl	ssRNA binding											GO:0003728		molecular_function											owl:Class	
GO:0030656	biolink:NamedThing	regulation of vitamin metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a vitamin, one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body.	tmpzr1t_l9r_go_relaxed.owl	regulation of vitamin metabolism													biological_process											owl:Class	
GO:0061708	biolink:NamedThing	tRNA-5-taurinomethyluridine 2-sulfurtransferase	Catalysis of 5-taurinomethyluridine in tRNA + a [protein]-S-sulfanylcysteine + ATP + a reduced electron acceptor = a 5-taurinomethyl-2-thiouridine in tRNA + a [protein]-L-cysteine + AMP + an oxidized electron acceptor + diphosphate + H+.	tmpzr1t_l9r_go_relaxed.owl					RHEA:47040|Reactome:R-HSA-6787447|MetaCyc:RXN-16821			dph	2015-06-16T09:02:23Z					molecular_function											owl:Class	
GO:0016783	biolink:NamedThing	sulfurtransferase activity	Catalysis of the transfer of sulfur atoms from one compound (donor) to another (acceptor).	tmpzr1t_l9r_go_relaxed.owl	tRNA sulfurtransferase activity|sulphurtransferase activity				Reactome:R-HSA-6782264|EC:2.8.1.-|Reactome:R-HSA-947538|Reactome:R-HSA-1614618									molecular_function											owl:Class	
GO:1900149	biolink:NamedThing	positive regulation of Schwann cell migration	Any process that activates or increases the frequency, rate or extent of Schwann cell migration.	tmpzr1t_l9r_go_relaxed.owl	upregulation of Schwann cell migration|up-regulation of Schwann cell migration|activation of Schwann cell migration|up regulation of Schwann cell migration							bf	2012-03-06T04:14:58Z					biological_process											owl:Class	
GO:1900147	biolink:NamedThing	regulation of Schwann cell migration	Any process that modulates the frequency, rate or extent of Schwann cell migration.	tmpzr1t_l9r_go_relaxed.owl								bf	2012-03-06T04:14:50Z					biological_process											owl:Class	
GO:1904881	biolink:NamedThing	cellular response to hydrogen sulfide	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrogen sulfide stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to sulfane|cellular response to dihydridosulfur							sl	2016-01-04T23:56:35Z					biological_process											owl:Class	
GO:0070887	biolink:NamedThing	cellular response to chemical stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus.	tmpzr1t_l9r_go_relaxed.owl						Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.		mah	2009-08-27T04:41:45Z					biological_process											owl:Class	
GO:2000850	biolink:NamedThing	negative regulation of glucocorticoid secretion	Any process that stops, prevents or reduces the frequency, rate or extent of glucocorticoid secretion.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-07-26T08:44:48Z					biological_process											owl:Class	
GO:1900553	biolink:NamedThing	asperfuranone catabolic process	The chemical reactions and pathways resulting in the breakdown of asperfuranone.	tmpzr1t_l9r_go_relaxed.owl	asperfuranone degradation|asperfuranone breakdown|asperfuranone catabolism							di	2012-05-15T01:31:35Z					biological_process											owl:Class	
GO:1901361	biolink:NamedThing	organic cyclic compound catabolic process	The chemical reactions and pathways resulting in the breakdown of organic cyclic compound.	tmpzr1t_l9r_go_relaxed.owl	organic cyclic compound breakdown|organic cyclic compound catabolism|organic cyclic compound degradation							bf	2012-09-14T09:05:04Z					biological_process											owl:Class	
GO:0014733	biolink:NamedThing	regulation of skeletal muscle adaptation	Any process in which skeletal muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. These adaptive events occur in both muscle fibers and associated structures (motoneurons and capillaries), and they involve alterations in regulatory mechanisms, contractile properties and metabolic capacities.	tmpzr1t_l9r_go_relaxed.owl	regulation of skeletal muscle plasticity													biological_process											owl:Class	
GO:0072184	biolink:NamedThing	renal vesicle progenitor cell differentiation	The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the renal vesicle progenitor cells of the kidney as it progresses from its formation to the mature state. A renal vesicle progenitor cell is a cell that will give rise to terminally differentiated cells of the renal vesicle without self-renewing.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-02-26T02:52:54Z					biological_process											owl:Class	
GO:0061005	biolink:NamedThing	cell differentiation involved in kidney development	The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the kidney as it progresses from its formation to the mature state.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-01-21T09:13:55Z					biological_process											owl:Class	
GO:1905086	biolink:NamedThing	negative regulation of bioluminescence	Any process that stops, prevents or reduces the frequency, rate or extent of bioluminescence.	tmpzr1t_l9r_go_relaxed.owl	down regulation of bioluminescence|down-regulation of bioluminescence|downregulation of bioluminescence|inhibition of bioluminescence							rph	2016-03-29T07:51:17Z					biological_process											owl:Class	
GO:0031324	biolink:NamedThing	negative regulation of cellular metabolic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances.	tmpzr1t_l9r_go_relaxed.owl	down regulation of cellular metabolic process|down-regulation of cellular metabolic process|downregulation of cellular metabolic process|inhibition of cellular metabolic process|negative regulation of cellular metabolism													biological_process											owl:Class	
GO:0018212	biolink:NamedThing	peptidyl-tyrosine modification	The modification of peptidyl-tyrosine.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0018193	biolink:NamedThing	peptidyl-amino acid modification	The alteration of an amino acid residue in a peptide.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0055019	biolink:NamedThing	negative regulation of cardiac muscle fiber development	Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle fiber development.	tmpzr1t_l9r_go_relaxed.owl	inhibition of cardiac muscle fiber development|negative regulation of heart muscle fiber development|negative regulation of cardiac muscle fibre development|downregulation of cardiac muscle fiber development|down-regulation of cardiac muscle fiber development|down regulation of cardiac muscle fiber development													biological_process											owl:Class	
GO:0055018	biolink:NamedThing	regulation of cardiac muscle fiber development	Any process that modulates the frequency, rate or extent of cardiac muscle fiber development.	tmpzr1t_l9r_go_relaxed.owl	regulation of heart muscle fiber development|regulation of cardiac muscle fibre development													biological_process											owl:Class	
GO:0000978	biolink:NamedThing	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Binding to a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site) located in cis relative to the transcription start site (i.e., on the same strand of DNA) of a gene transcribed by RNA polymerase II.	tmpzr1t_l9r_go_relaxed.owl	RNA polymerase II distal enhancer sequence-specific DNA binding|RNA polymerase II promoter proximal region sequence-specific DNA binding|RNA polymerase II proximal promoter sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding|RNA polymerase II upstream activating sequence (UAS) sequence-specific DNA binding					Note that the phrase "upstream activating sequence", or UAS is often used in S. cerevisiae literature to refer to cis-regulatory sequences. In bacteria such as E. coli, the phrase "upstream activating sequence", or UAS is usually a synonym for "enhancer".		krc	2010-08-10T02:17:19Z			GO:0000980		molecular_function											owl:Class	
GO:0000987	biolink:NamedThing	cis-regulatory region sequence-specific DNA binding	Binding to a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site) located in cis relative to the transcription start site (i.e., on the same strand of DNA) of a gene transcribed by some RNA polymerase. The proximal promoter is in cis with and relatively close to the core promoter.	tmpzr1t_l9r_go_relaxed.owl	bacterial-type RNA polymerase enhancer sequence-specific DNA binding|proximal promoter sequence-specific DNA binding|bacterial-type proximal promoter sequence-specific DNA binding|eubacterial-type RNA polymerase regulatory transcription factor sequence-specific DNA binding|core promoter proximal region DNA binding|bacterial-type RNA polymerase core promoter proximal region sequence-specific DNA binding|cis-regulatory region binding|promoter proximal region sequence-specific DNA binding|core promoter proximal region sequence-specific DNA binding|bacterial-type cis-regulatory region sequence-specific DNA binding|enhancer sequence-specific DNA binding|bacterial-type RNA polymerase upstream activating sequence (UAS) sequence-specific DNA binding|enhancer binding							bf	2010-02-26T10:17:00Z			GO:0001150|GO:0000986|GO:0001158|GO:0001159|GO:0035326		molecular_function											owl:Class	
GO:1905698	biolink:NamedThing	positive regulation of polysome binding	Any process that activates or increases the frequency, rate or extent of polysome binding.	tmpzr1t_l9r_go_relaxed.owl	activation of polyribosome binding|up-regulation of polyribosome binding|up regulation of polysome binding|up-regulation of polysome binding|upregulation of polyribosome binding|positive regulation of polyribosome binding|activation of polysome binding|upregulation of polysome binding|up regulation of polyribosome binding							bc	2016-11-14T23:26:37Z					biological_process											owl:Class	
GO:1905696	biolink:NamedThing	regulation of polysome binding	Any process that modulates the frequency, rate or extent of polysome binding.	tmpzr1t_l9r_go_relaxed.owl	regulation of polyribosome binding							bc	2016-11-14T23:26:22Z					biological_process											owl:Class	
GO:1990611	biolink:NamedThing	regulation of cytoplasmic translational initiation in response to stress	Modulation of the frequency, rate or extent of cytoplasmic translational initiation as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).	tmpzr1t_l9r_go_relaxed.owl								vw	2015-01-20T13:04:14Z					biological_process											owl:Class	
GO:1990497	biolink:NamedThing	regulation of cytoplasmic translation in response to stress	Modulation of the frequency, rate or extent of cytoplasmic translation as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).	tmpzr1t_l9r_go_relaxed.owl								vw	2014-09-26T11:11:29Z					biological_process											owl:Class	
GO:0003251	biolink:NamedThing	positive regulation of cell proliferation involved in heart valve morphogenesis	Any process that increases the rate, frequency or extent of cell proliferation that contributes to the shaping of a heart valve.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-10-13T02:07:20Z					biological_process											owl:Class	
GO:1904869	biolink:NamedThing	regulation of protein localization to Cajal body	Any process that modulates the frequency, rate or extent of protein localization to Cajal body.	tmpzr1t_l9r_go_relaxed.owl	regulation of protein localisation to Cajal body|regulation of protein localisation in Cajal body|regulation of protein localization in Cajal body							nc	2015-12-18T11:17:31Z					biological_process											owl:Class	
GO:1900180	biolink:NamedThing	regulation of protein localization to nucleus	Any process that modulates the frequency, rate or extent of protein localization to nucleus.	tmpzr1t_l9r_go_relaxed.owl	regulation of protein localization in cell nucleus|regulation of protein localization in nucleus|regulation of protein localisation to nucleus							bf	2012-03-12T01:23:44Z					biological_process											owl:Class	
GO:0047100	biolink:NamedThing	glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) activity	Catalysis of the reaction: phosphate + NADP+ + glyceraldehyde-3-phosphate = NADPH + 3-phospho-D-glyceroyl-phosphate.	tmpzr1t_l9r_go_relaxed.owl	NADP-dependent glyceraldehyde phosphate dehydrogenase activity|triosephosphate dehydrogenase (NADP+) activity|triosephosphate dehydrogenase (NADP(+)) activity|glyceraldehyde phosphate dehydrogenase (nicotinamide adenine dinucleotide phosphate) (phosphorylating)|triosephosphate dehydrogenase (NADP)|NADP-triose phosphate dehydrogenase activity|dehydrogenase, glyceraldehyde phosphate (nicotinamide adenine dinucleotide phosphate) (phosphorylating)|D-glyceraldehyde-3-phosphate:NADP+ oxidoreductase (phosphorylating)|NADP-dependent glyceraldehyde-3-phosphate dehydrogenase activity				EC:1.2.1.13|RHEA:10296|MetaCyc:1.2.1.13-RXN									molecular_function											owl:Class	
GO:0043891	biolink:NamedThing	glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity	Catalysis of the reaction: D-glyceraldehyde 3-phosphate + phosphate + NAD(P)+ = 3-phospho-D-glyceroyl phosphate + NAD(P)H + H+.	tmpzr1t_l9r_go_relaxed.owl	glyceraldehyde-3-phosphate dehydrogenase (NAD(P)) (phosphorylating)|NAD(P)-dependent glyceraldehyde-3-phosphate dehydrogenase activity|triosephosphate dehydrogenase (NAD(P))|D-glyceraldehyde 3-phosphate:NAD(P)+ oxidoreductase (phosphorylating)|triosephosphate dehydrogenase (NAD(P)+)				MetaCyc:GAPDHSYNEC-RXN|EC:1.2.1.59									molecular_function											owl:Class	
GO:0072227	biolink:NamedThing	metanephric macula densa development	The process whose specific outcome is the progression of the metanephric macula densa over time, from its formation to the mature structure. The metanephric macula densa is an area of specialized cells in the distal tubule of the metanephros that makes contact with the vascular pole of the glomerulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-03-18T03:37:26Z					biological_process											owl:Class	
GO:0072024	biolink:NamedThing	macula densa development	The process whose specific outcome is the progression of the macula densa over time, from its formation to the mature structure. The macula densa is an area of specialized cells in the distal tubule that makes contact with the vascular pole of the glomerulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-01-25T02:40:15Z					biological_process											owl:Class	
GO:0060757	biolink:NamedThing	adult foraging behavior	Behavior by which an adult locates food.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-06-22T02:50:56Z					biological_process											owl:Class	
GO:0060756	biolink:NamedThing	foraging behavior	Behavior by which an organism locates food.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-06-22T02:46:25Z					biological_process											owl:Class	
GO:0106397	biolink:NamedThing	positive regulation of R7 cell fate commitment	Any process that activates or increases the frequency, rate or extent of R7 cell fate commitment.	tmpzr1t_l9r_go_relaxed.owl								hjd	2021-10-08T19:14:40Z					biological_process											owl:Class	
GO:0010455	biolink:NamedThing	positive regulation of cell fate commitment	Any process that activates, maintains or increases the frequency or rate of cell fate commitment. Cell fate commitment is the commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0033244	biolink:NamedThing	regulation of penicillin metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving any antibiotic that contains the condensed beta-lactamthiazolidine ring system.	tmpzr1t_l9r_go_relaxed.owl	regulation of penicillin metabolism													biological_process											owl:Class	
GO:0034248	biolink:NamedThing	regulation of cellular amide metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving amides.	tmpzr1t_l9r_go_relaxed.owl	regulation of amide metabolism													biological_process											owl:Class	
GO:0043480	biolink:NamedThing	pigment accumulation in tissues	The aggregation of coloring matter in a particular location in a tissue, occurring in response to an external stimulus.	tmpzr1t_l9r_go_relaxed.owl	organismal pigment accumulation													biological_process											owl:Class	
GO:0032501	biolink:NamedThing	multicellular organismal process	Any biological process, occurring at the level of a multicellular organism, pertinent to its function.	tmpzr1t_l9r_go_relaxed.owl	single-multicellular organism process|organismal physiological process							jl	2012-09-19T16:07:47Z			GO:0050874|GO:0044707		biological_process											owl:Class	
GO:0031969	biolink:NamedThing	chloroplast membrane	Either of the lipid bilayers that surround a chloroplast and form the chloroplast envelope.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Chloroplast_membrane									cellular_component											owl:Class	
GO:0042170	biolink:NamedThing	plastid membrane	Either of the lipid bilayers that surround a plastid and form the plastid envelope.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0051321	biolink:NamedThing	meiotic cell cycle	Progression through the phases of the meiotic cell cycle, in which canonically a cell replicates to produce four offspring with half the chromosomal content of the progenitor cell via two nuclear divisions.	tmpzr1t_l9r_go_relaxed.owl	meiosis				Wikipedia:Meiosis	Note that this term should not be confused with 'GO:0140013 ; meiotic nuclear division'. 'GO:0051321 ; meiotic cell cycle represents the entire mitotic cell cycle, while 'GO:0140013 meiotic nuclear division' specifically represents the actual nuclear division step of the mitotic cell cycle.						GO:0007126		biological_process											owl:Class	
GO:0022414	biolink:NamedThing	reproductive process	A biological process that directly contributes to the process of producing new individuals by one or two organisms. The new individuals inherit some proportion of their genetic material from the parent or parents.	tmpzr1t_l9r_go_relaxed.owl	single organism reproductive process							jl	2012-09-19T15:56:06Z			GO:0044702		biological_process											owl:Class	
GO:0021552	biolink:NamedThing	midbrain-hindbrain boundary structural organization	The process that contributes to the act of creating the structural organization of the midbrain-hindbrain boundary structure. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate.	tmpzr1t_l9r_go_relaxed.owl	midbrain-hindbrain boundary structural organisation|isthmus structural organization|MHB structural organization													biological_process											owl:Class	
GO:0048532	biolink:NamedThing	anatomical structure arrangement	The process that gives rise to the configuration of the constituent parts of an anatomical structure. This process pertains to the physical shaping of a rudimentary structure. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome.	tmpzr1t_l9r_go_relaxed.owl	organization of an anatomical structure|structural organization|anatomical structure organization|anatomical structure structural organization													biological_process											owl:Class	
GO:1903343	biolink:NamedThing	positive regulation of meiotic DNA double-strand break formation	Any process that activates or increases the frequency, rate or extent of meiotic DNA double-strand break formation.	tmpzr1t_l9r_go_relaxed.owl	activation of meiotic DNA double-strand break formation|upregulation of meiotic DNA double-strand break formation|up regulation of meiotic DNA double-strand break formation|up-regulation of meiotic DNA double-strand break formation							mcc	2014-08-18T21:32:11Z					biological_process											owl:Class	
GO:0045935	biolink:NamedThing	positive regulation of nucleobase-containing compound metabolic process	Any cellular process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism|upregulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process|positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process|stimulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process|activation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process|up-regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process|up regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process													biological_process											owl:Class	
GO:2001102	biolink:NamedThing	hexasaccharide transport	The directed movement of a hexasaccharideacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl								jl	2011-09-21T02:20:31Z					biological_process											owl:Class	
GO:0015772	biolink:NamedThing	oligosaccharide transport	The directed movement of oligosaccharides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Oligosaccharides are molecules with between two and (about) 20 monosaccharide residues connected by glycosidic linkages.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0061669	biolink:NamedThing	spontaneous neurotransmitter secretion	Neurotransmitter secretion that occurs in the absence of the action of a secretagogue or a presynaptic action potential.	tmpzr1t_l9r_go_relaxed.owl	stimulus-independent neurotransmitter secretion							dph	2014-11-17T07:52:35Z					biological_process											owl:Class	
GO:0007269	biolink:NamedThing	neurotransmitter secretion	The regulated release of neurotransmitter from the presynapse into the synaptic cleft via calcium-regulated exocytosis during synaptic transmission.	tmpzr1t_l9r_go_relaxed.owl	neurotransmitter release|neurotransmitter secretory pathway					A neurotransmitter is any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell. Among the many substances that have the properties of a neurotransmitter are acetylcholine, noradrenaline, adrenaline, dopamine, glycine, gamma-aminobutyrate, glutamic acid, substance P, enkephalins, endorphins and serotonin.						GO:0010554		biological_process											owl:Class	
GO:2000335	biolink:NamedThing	regulation of endothelial microparticle formation	Any process that modulates the frequency, rate or extent of endothelial microparticle formation.	tmpzr1t_l9r_go_relaxed.owl	regulation of endothelial microparticle generation|regulation of endothelial microparticle release							mah	2011-01-31T11:20:26Z					biological_process											owl:Class	
GO:0071616	biolink:NamedThing	acyl-CoA biosynthetic process	The chemical reactions and pathways resulting in the formation of acyl-CoA, any derivative of coenzyme A in which the sulfhydryl group is in thiolester linkage with an acyl group.	tmpzr1t_l9r_go_relaxed.owl	acyl-CoA synthesis|acyl-CoA biosynthesis|acyl-CoA formation|acyl-CoA anabolism							mah	2010-02-08T04:43:31Z					biological_process											owl:Class	
GO:0006637	biolink:NamedThing	acyl-CoA metabolic process	The chemical reactions and pathways involving acyl-CoA, any derivative of coenzyme A in which the sulfhydryl group is in thiolester linkage with an acyl group.	tmpzr1t_l9r_go_relaxed.owl	acyl-CoA metabolism													biological_process											owl:Class	
GO:0055044	biolink:NamedThing	symplast	The interconnected cell membranes and intracellular regions of a plant. The interconnections occur via the plasmodesmata.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Symplast									cellular_component											owl:Class	
GO:0110165	biolink:NamedThing	cellular anatomical entity	A part of a cellular organism that is either an immaterial entity or a material entity with granularity above the level of a protein complex but below that of an anatomical system. Or, a substance produced by a cellular organism with granularity above the level of a protein complex.	tmpzr1t_l9r_go_relaxed.owl								kmv	2019-08-12T18:01:37Z					cellular_component											owl:Class	
GO:0033497	biolink:NamedThing	sinapate biosynthetic process	The chemical reactions and pathways resulting in the formation of sinapate, (2E)-3-(4-hydroxy-3,5-dimethoxyphenyl)prop-2-enoate.	tmpzr1t_l9r_go_relaxed.owl	sinapate biosynthesis|sinapate formation|sinapate synthesis|sinapate anabolism				MetaCyc:PWY-5168									biological_process											owl:Class	
GO:0072330	biolink:NamedThing	monocarboxylic acid biosynthetic process	The chemical reactions and pathways resulting in the formation of monocarboxylic acids, any organic acid containing one carboxyl (-COOH) group.	tmpzr1t_l9r_go_relaxed.owl	monocarboxylic acid synthesis|monocarboxylic acid biosynthesis|monocarboxylic acid formation|monocarboxylic acid anabolism							mah	2010-11-02T04:51:32Z					biological_process											owl:Class	
GO:0030955	biolink:NamedThing	potassium ion binding	Binding to a potassium ion (K+).	tmpzr1t_l9r_go_relaxed.owl	K ion binding													molecular_function											owl:Class	
GO:0031420	biolink:NamedThing	alkali metal ion binding	Binding to an alkali metal ion; alkali metals are those elements in group Ia of the periodic table, with the exception of hydrogen.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0045723	biolink:NamedThing	positive regulation of fatty acid biosynthetic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of fatty acids.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of fatty acid biosynthesis|activation of fatty acid biosynthetic process|up regulation of fatty acid biosynthetic process|positive regulation of fatty acid formation|up-regulation of fatty acid biosynthetic process|positive regulation of fatty acid synthesis|upregulation of fatty acid biosynthetic process|positive regulation of fatty acid anabolism|stimulation of fatty acid biosynthetic process													biological_process											owl:Class	
GO:0045923	biolink:NamedThing	positive regulation of fatty acid metabolic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving fatty acids.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of fatty acid metabolism|activation of fatty acid metabolic process|upregulation of fatty acid metabolic process|up regulation of fatty acid metabolic process|up-regulation of fatty acid metabolic process|stimulation of fatty acid metabolic process													biological_process											owl:Class	
GO:0045949	biolink:NamedThing	positive regulation of phosphorus utilization	Any process that activates or increases the frequency, rate or extent of phosphorus utilization.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of phosphorus utilization|up regulation of phosphorus utilization|stimulation of phosphorus utilization|upregulation of phosphorus utilization|activation of phosphorus utilization													biological_process											owl:Class	
GO:0002223	biolink:NamedThing	stimulatory C-type lectin receptor signaling pathway	Any series of molecular signals generated as a consequence of binding to a C-type lectin receptor capable of cellular activation.	tmpzr1t_l9r_go_relaxed.owl	stimulatory C-type lectin receptor signalling pathway|stimulatory Ly49 family receptor signaling pathway													biological_process											owl:Class	
GO:0002220	biolink:NamedThing	innate immune response activating cell surface receptor signaling pathway	Any series of molecular signals leading to activation of the innate immune response generated as a consequence of binding to a cell surface receptor.	tmpzr1t_l9r_go_relaxed.owl	innate immune response activating cell surface receptor signalling pathway|activation of innate immune response by cell surface receptor signaling pathway													biological_process											owl:Class	
GO:1900270	biolink:NamedThing	positive regulation of reverse transcription	Any process that activates or increases the frequency, rate or extent of reverse transcription.	tmpzr1t_l9r_go_relaxed.owl	activation of reverse transcription|upregulation of reverse transcription|up-regulation of reverse transcription|up regulation of reverse transcription							tb	2012-04-03T11:13:43Z					biological_process											owl:Class	
GO:1900268	biolink:NamedThing	regulation of reverse transcription	Any process that modulates the frequency, rate or extent of reverse transcription.	tmpzr1t_l9r_go_relaxed.owl								tb	2012-04-03T11:13:26Z					biological_process											owl:Class	
GO:1901300	biolink:NamedThing	positive regulation of hydrogen peroxide-mediated programmed cell death	Any process that activates or increases the frequency, rate or extent of hydrogen peroxide-mediated programmed cell death.	tmpzr1t_l9r_go_relaxed.owl	activation of hydrogen peroxide-mediated programmed cell death|upregulation of hydrogen peroxide-mediated programmed cell death|up regulation of hydrogen peroxide-mediated programmed cell death|up-regulation of hydrogen peroxide-mediated programmed cell death							vk	2012-08-21T09:45:29Z					biological_process											owl:Class	
GO:0043068	biolink:NamedThing	positive regulation of programmed cell death	Any process that activates or increases the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes.	tmpzr1t_l9r_go_relaxed.owl	activation of programmed cell death|stimulation of programmed cell death|upregulation of programmed cell death|up-regulation of programmed cell death|up regulation of programmed cell death|positive regulation of non-apoptotic programmed cell death											GO:0043071		biological_process											owl:Class	
GO:0009505	biolink:NamedThing	plant-type cell wall	A more or less rigid stucture lying outside the cell membrane of a cell and composed of cellulose and pectin and other organic and inorganic substances.	tmpzr1t_l9r_go_relaxed.owl	cellulose and pectin-containing cell wall|plant cell wall													cellular_component											owl:Class	
GO:0005618	biolink:NamedThing	cell wall	The rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal, most prokaryotic cells and some protozoan parasites, maintaining their shape and protecting them from osmotic lysis. In plants it is made of cellulose and, often, lignin; in fungi it is composed largely of polysaccharides; in bacteria it is composed of peptidoglycan; in protozoan parasites such as Giardia species, it's made of carbohydrates and proteins.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/21669			Wikipedia:Cell_wall	Not to be used for manual annotation.  Please choose a more specific term: for bacteria, annotate to GO:0009274; peptidoglycan-based cell wall, for  plants: annotate to GO:0009505 ; plant-type cell wall, for fungi: GO:0009277 ; fungal-type cell wall, and for archae, use GO:0030115 S-layer (see PMID:31214995).								cellular_component											owl:Class	
GO:0009710	biolink:NamedThing	tropane alkaloid biosynthetic process	The chemical reactions and pathways resulting in the breakdown of tropane alkaloids, compounds containing the 8-methyl-8-azabicyclo(3.2.1)octane ring system.	tmpzr1t_l9r_go_relaxed.owl	tropane alkaloid anabolism|tropane alkaloid biosynthesis|tropane alkaloid synthesis|tropane alkaloid formation													biological_process											owl:Class	
GO:1901362	biolink:NamedThing	organic cyclic compound biosynthetic process	The chemical reactions and pathways resulting in the formation of organic cyclic compound.	tmpzr1t_l9r_go_relaxed.owl	organic cyclic compound biosynthesis|organic cyclic compound formation|organic cyclic compound anabolism|organic cyclic compound synthesis							bf	2012-09-14T09:05:22Z					biological_process											owl:Class	
GO:0045836	biolink:NamedThing	positive regulation of meiotic nuclear division	Any process that activates or increases the frequency, rate or extent of meiosis.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of meiosis|stimulation of meiosis|activation of meiosis|upregulation of meiosis|positive regulation of meiosis|up regulation of meiosis													biological_process											owl:Class	
GO:0051446	biolink:NamedThing	positive regulation of meiotic cell cycle	Any process that activates or increases the frequency, rate or extent of progression through the meiotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl	upregulation of progression through meiotic cell cycle|stimulation of progression through meiotic cell cycle|positive regulation of progression through meiotic cell cycle|positive regulation of meiotic cell cycle progression|activation of progression through meiotic cell cycle|up regulation of progression through meiotic cell cycle|up-regulation of progression through meiotic cell cycle													biological_process											owl:Class	
GO:0060668	biolink:NamedThing	regulation of branching involved in salivary gland morphogenesis by extracellular matrix-epithelial cell signaling	Any process that modulates the rate, frequency, or extent of salivary gland branching as a result of the transfer of information from the extracellular matrix to the epithelium of the salivary gland.	tmpzr1t_l9r_go_relaxed.owl	regulation of branching involved in salivary gland morphogenesis by extracellular matrix-epithelial cell signalling							dph	2009-06-01T09:47:56Z					biological_process											owl:Class	
GO:0060693	biolink:NamedThing	regulation of branching involved in salivary gland morphogenesis	Any process that modulates the rate, frequency, or extent of branching morphogenesis in the salivary gland epithelium.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-06-08T01:14:44Z					biological_process											owl:Class	
GO:0019460	biolink:NamedThing	glutamine catabolic process to fumarate	The chemical reactions and pathways resulting in the breakdown of glutamine into other compounds, including fumarate.	tmpzr1t_l9r_go_relaxed.owl	glutamine breakdown to fumarate|glutamine degradation to fumarate|glutamate catabolic process to fumarate													biological_process											owl:Class	
GO:0006543	biolink:NamedThing	glutamine catabolic process	The chemical reactions and pathways resulting in the breakdown of glutamine, 2-amino-4-carbamoylbutanoic acid.	tmpzr1t_l9r_go_relaxed.owl	glutamine catabolism|glutamine breakdown|glutamine degradation													biological_process											owl:Class	
GO:0062091	biolink:NamedThing	Ycf2/FtsHi complex	A protein complex located in the chloroplast inner membrane and facing the stroma that is associated with the chloroplast inner membrane translocase complex and provides the ATPase motor activity to drive import of proteins into the chloroplast stroma.	tmpzr1t_l9r_go_relaxed.owl	TIC complex associated chloroplast protein import motor							dph	2018-11-08T20:06:11Z					cellular_component											owl:Class	
GO:1904949	biolink:NamedThing	ATPase complex	A protein complex which is capable of ATPase activity.	tmpzr1t_l9r_go_relaxed.owl	VPS4 complex					An example of this is VPS4 in Saccharomyces cerevisiae (UniProt ID P52917) in PMID:9606181 (inferred from direct assay).		bhm	2016-02-04T22:13:32Z					cellular_component											owl:Class	
GO:0007131	biolink:NamedThing	reciprocal meiotic recombination	The cell cycle process in which double strand breaks are formed and repaired through a single or double Holliday junction intermediate. This results in the equal exchange of genetic material between non-sister chromatids in a pair of homologous chromosomes. These reciprocal recombinant products ensure the proper segregation of homologous chromosomes during meiosis I and create genetic diversity.	tmpzr1t_l9r_go_relaxed.owl	gene conversion with reciprocal crossover|female meiotic recombination											GO:0007145|GO:0000021		biological_process											owl:Class	
GO:0140527	biolink:NamedThing	reciprocal homologous recombination	A DNA recombination process that results in the bidirectional exchange of genetic material between highly homologous DNA molecules.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/18777						pg	2020-09-29T15:08:11Z					biological_process											owl:Class	
GO:0019510	biolink:NamedThing	S-adenosylhomocysteine catabolic process	The chemical reactions and pathways resulting in the breakdown of S-adenosylhomocysteine, forming homocysteine and then methionine.	tmpzr1t_l9r_go_relaxed.owl	S-adenosylhomocysteine breakdown|S-adenosylhomocysteine catabolism|S-adenosylhomocysteine degradation				MetaCyc:ADENOSYLHOMOCYSCAT-PWY									biological_process											owl:Class	
GO:0042219	biolink:NamedThing	cellular modified amino acid catabolic process	The chemical reactions and pathways resulting in the breakdown of compounds derived from amino acids, organic acids containing one or more amino substituents.	tmpzr1t_l9r_go_relaxed.owl	cellular modified amino acid degradation|cellular modified amino acid catabolism|cellular amino acid derivative degradation|amino acid derivative catabolic process|cellular amino acid derivative breakdown|cellular amino acid derivative catabolic process|modified amino acid catabolism|modified amino acid catabolic process|cellular amino acid derivative catabolism|cellular modified amino acid breakdown													biological_process											owl:Class	
GO:0110045	biolink:NamedThing	negative regulation of cell cycle switching, mitotic to meiotic cell cycle	Any process that stops, prevents, or reduces the frequency, rate, or extent of mitotic to meiotic cell cycle switching, the process in which a cell switches cell cycle mode from mitotic to meiotic division.	tmpzr1t_l9r_go_relaxed.owl								kmv	2017-08-08T21:33:28Z					biological_process											owl:Class	
GO:0110044	biolink:NamedThing	regulation of cell cycle switching, mitotic to meiotic cell cycle	Any process that modulates the frequency, rate, or extent of mitotic to meiotic cell cycle switching, the process in which a cell switches cell cycle mode from mitotic to meiotic division.	tmpzr1t_l9r_go_relaxed.owl	sexual differentiation	https://github.com/geneontology/go-ontology/issues/20926						kmv	2017-08-08T21:24:45Z					biological_process											owl:Class	
GO:0120022	biolink:NamedThing	glucagon family peptide binding	Binding to a member of the glucagon family peptide hormone (e.g. glucagon, glucagon-like peptides, oxyntomodulin, glicentin, ADCYAP1, GHRH, secretin, VIP, GIP).	tmpzr1t_l9r_go_relaxed.owl	glucagon-like peptide binding|glucagon binding	https://github.com/geneontology/go-ontology/issues/13143|https://github.com/geneontology/go-ontology/issues/21327						krc	2017-03-17T14:46:29Z			GO:0120024		molecular_function											owl:Class	
GO:0017046	biolink:NamedThing	peptide hormone binding	Binding to a peptide with hormonal activity in animals.	tmpzr1t_l9r_go_relaxed.owl	polypeptide hormone binding													molecular_function											owl:Class	
GO:0090153	biolink:NamedThing	regulation of sphingolipid biosynthetic process	Any process that modulates the rate, frequency or extent of sphingolipid biosynthesis. Sphingolipid biosynthesis is the chemical reactions and pathways resulting in the formation of sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid).	tmpzr1t_l9r_go_relaxed.owl								tb	2009-12-08T03:25:49Z					biological_process											owl:Class	
GO:0051171	biolink:NamedThing	regulation of nitrogen compound metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nitrogen or nitrogenous compounds.	tmpzr1t_l9r_go_relaxed.owl	regulation of nitrogen metabolic process|regulation of nitrogen metabolism													biological_process											owl:Class	
GO:0019912	biolink:NamedThing	cyclin-dependent protein kinase activating kinase activity	Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein; increases the activity of a cyclin-dependent protein kinase (CDK).	tmpzr1t_l9r_go_relaxed.owl	cyclin-dependent protein kinase activating kinase, intrinsic catalyst activity|cdk-activating kinase activity|CAK											GO:0019913		molecular_function											owl:Class	
GO:0030295	biolink:NamedThing	protein kinase activator activity	Binds to and increases the activity of a protein kinase, an enzyme which phosphorylates a protein.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1905465	biolink:NamedThing	regulation of G-quadruplex DNA unwinding	Any process that modulates the frequency, rate or extent of G-quadruplex DNA unwinding.	tmpzr1t_l9r_go_relaxed.owl								ans	2016-09-19T12:15:45Z					biological_process											owl:Class	
GO:0120261	biolink:NamedThing	regulation of heterochromatin organization	Any process that modulates the frequency, rate, extent or location of heterochromatin organization.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/20020						krc	2020-09-29T20:00:04Z					biological_process											owl:Class	
GO:1902275	biolink:NamedThing	regulation of chromatin organization	Any process that modulates the frequency, rate or extent of chromatin organization.	tmpzr1t_l9r_go_relaxed.owl	regulation of chromatin modification|regulation of chromatin organisation|regulation of establishment or maintenance of chromatin architecture							bf	2013-07-01T13:21:52Z			GO:1903308		biological_process											owl:Class	
GO:0000939	biolink:NamedThing	inner kinetochore	The region of a kinetochore closest to centromeric DNA; in mammals the CREST antigens (CENP proteins) are found in this layer; this layer may help define underlying centromeric chromatin structure and position of the kinetochore on the chromosome.	tmpzr1t_l9r_go_relaxed.owl	condensed nuclear chromosome inner kinetochore|inner kinetochore of condensed chromosome|inner kinetochore of condensed nuclear chromosome|condensed chromosome inner kinetochore|inner centromere core complex|inner kinetochore plate	https://github.com/geneontology/go-ontology/issues/21126										GO:0000941		cellular_component											owl:Class	
GO:0002763	biolink:NamedThing	positive regulation of myeloid leukocyte differentiation	Any process that activates or increases the frequency, rate, or extent of myeloid leukocyte differentiation.	tmpzr1t_l9r_go_relaxed.owl	upregulation of myeloid leukocyte differentiation|up regulation of myeloid leukocyte differentiation|up-regulation of myeloid leukocyte differentiation|activation of myeloid leukocyte differentiation|stimulation of myeloid leukocyte differentiation													biological_process											owl:Class	
GO:0045639	biolink:NamedThing	positive regulation of myeloid cell differentiation	Any process that activates or increases the frequency, rate or extent of myeloid cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	up regulation of myeloid cell differentiation|upregulation of myeloid cell differentiation|stimulation of myeloid cell differentiation|up-regulation of myeloid cell differentiation|activation of myeloid cell differentiation													biological_process											owl:Class	
GO:0002431	biolink:NamedThing	Fc receptor mediated stimulatory signaling pathway	A series of molecular signals generated as a consequence of a the binding of the Fc portion of an immunoglobulin by an Fc receptor capable of activating or perpetuating an immune response. The Fc portion of an immunoglobulin is its C-terminal constant region.	tmpzr1t_l9r_go_relaxed.owl	Fc receptor mediated stimulatory signalling pathway|Fc-receptor mediated stimulatory signaling pathway													biological_process											owl:Class	
GO:0002429	biolink:NamedThing	immune response-activating cell surface receptor signaling pathway	A series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of a cell capable of activating or perpetuating an immune response.	tmpzr1t_l9r_go_relaxed.owl	activation of immune response by cell surface receptor signaling pathway|immune response-activating cell surface receptor signalling pathway													biological_process											owl:Class	
GO:0052802	biolink:NamedThing	nitroimidazole metabolic process	The chemical reactions and pathways involving nitroimidazoles, imidazole derivatives with a nitro group attached to one ring.	tmpzr1t_l9r_go_relaxed.owl	nitroimidazole metabolism													biological_process											owl:Class	
GO:0052803	biolink:NamedThing	imidazole-containing compound metabolic process	The chemical reactions and pathways involving imidazoles, five-membered organic heterocycle containing two nitrogen atoms at positions 1 and 3, or any of its derivatives; compounds containing an imidazole skeleton.	tmpzr1t_l9r_go_relaxed.owl	imidazole metabolism													biological_process											owl:Class	
GO:0043388	biolink:NamedThing	positive regulation of DNA binding	Any process that increases the frequency, rate or extent of DNA binding. DNA binding is any process in which a gene product interacts selectively with DNA (deoxyribonucleic acid).	tmpzr1t_l9r_go_relaxed.owl	stimulation of DNA binding|upregulation of DNA binding|up regulation of DNA binding|up-regulation of DNA binding|activation of DNA binding													biological_process											owl:Class	
GO:0051101	biolink:NamedThing	regulation of DNA binding	Any process that modulates the frequency, rate or extent of DNA binding. DNA binding is any process in which a gene product interacts selectively with DNA (deoxyribonucleic acid).	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1901886	biolink:NamedThing	2-hydroxybenzoyl-CoA catabolic process	The chemical reactions and pathways resulting in the breakdown of 2-hydroxybenzoyl-CoA.	tmpzr1t_l9r_go_relaxed.owl	2-hydroxybenzoyl-CoA catabolism|2-hydroxybenzoyl-CoA degradation|2-hydroxybenzoyl-CoA breakdown							ms	2013-02-06T14:06:08Z					biological_process											owl:Class	
GO:0019336	biolink:NamedThing	phenol-containing compound catabolic process	The chemical reactions and pathways resulting in the breakdown of a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring.	tmpzr1t_l9r_go_relaxed.owl	phenol-containing compound breakdown|phenol-containing compound catabolism|phenol-containing compound degradation				MetaCyc:PHENOLDEG-PWY									biological_process											owl:Class	
GO:0019498	biolink:NamedThing	n-octane oxidation	The chemical reactions and pathways resulting in the conversion of n-octane to octanoyl-CoA.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:P221-PWY									biological_process											owl:Class	
GO:0018939	biolink:NamedThing	n-octane metabolic process	The chemical reactions and pathways involving n-octane, the 8 carbon straight chain alkane used in organic syntheses, calibrations, and azeotropic distillations. It is a common component of gasoline and other petroleum products and the engine fuel antiknocking properties of an isomer of n-octane are used as a comparative standard in the Octane Rating System.	tmpzr1t_l9r_go_relaxed.owl	n-octane metabolism				UM-BBD_pathwayID:oct									biological_process											owl:Class	
GO:1902461	biolink:NamedThing	negative regulation of mesenchymal stem cell proliferation	Any process that stops, prevents or reduces the frequency, rate or extent of mesenchymal stem cell proliferation.	tmpzr1t_l9r_go_relaxed.owl	downregulation of mesenchymal stem cell proliferation|down regulation of mesenchymal stem cell proliferation|down regulation of MSC proliferation|negative regulation of MSC proliferation|inhibition of mesenchymal stem cell proliferation|downregulation of MSC proliferation|down-regulation of mesenchymal stem cell proliferation|down-regulation of MSC proliferation|inhibition of MSC proliferation							pm	2013-10-22T10:01:08Z					biological_process											owl:Class	
GO:2000987	biolink:NamedThing	positive regulation of behavioral fear response	Any process that activates or increases the frequency, rate or extent of behavioral fear response.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of behavioural fear response							yaf	2011-08-08T09:16:39Z					biological_process											owl:Class	
GO:1901349	biolink:NamedThing	glucosinolate transport	The directed movement of a glucosinolate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl								tb	2012-09-07T22:44:34Z					biological_process											owl:Class	
GO:0072348	biolink:NamedThing	sulfur compound transport	The directed movement of compounds that contain sulfur, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	sulfur-containing compound transport							mah	2010-11-11T11:43:56Z					biological_process											owl:Class	
GO:1900784	biolink:NamedThing	fumiquinazoline F biosynthetic process	The chemical reactions and pathways resulting in the formation of fumiquinazoline F.	tmpzr1t_l9r_go_relaxed.owl	fumiquinazoline F anabolism|fumiquinazoline F formation|fumiquinazoline F synthesis|fumiquinazoline F biosynthesis							di	2012-06-04T09:31:34Z					biological_process											owl:Class	
GO:0042435	biolink:NamedThing	indole-containing compound biosynthetic process	The chemical reactions and pathways resulting in the formation of compounds that contain an indole (2,3-benzopyrrole) skeleton.	tmpzr1t_l9r_go_relaxed.owl	indole derivative biosynthetic process|indole-containing compound synthesis|indole-containing compound biosynthesis|indole-containing compound anabolism|indole derivative biosynthesis|indole-containing compound formation													biological_process											owl:Class	
GO:0046859	biolink:NamedThing	hydrogenosomal membrane	The lipid bilayer surrounding a hydrogenosome.	tmpzr1t_l9r_go_relaxed.owl	hydrogenosome membrane													cellular_component											owl:Class	
GO:0098588	biolink:NamedThing	bounding membrane of organelle	The lipid bilayer that forms the outer-most layer of an organelle.	tmpzr1t_l9r_go_relaxed.owl						Examples include the outer membranes of double membrane bound organelles such as mitochondria as well as the bounding membranes of single-membrane bound organelles such as lysosomes.		dos	2014-02-26T13:41:31Z					cellular_component											owl:Class	
GO:0048575	biolink:NamedThing	short-day photoperiodism, flowering	A change from vegetative to reproductive phase as a result of detection of, or exposure to, a period of light that falls short of the critical day length. The critical day length varies between species. Although the term is short-day is used, most species actually respond to the duration of the night, so that the response will occur when a period of darkness exceeds the number of hours defined by 24 minus the critical day length.	tmpzr1t_l9r_go_relaxed.owl	short-day photoperiodic control of flowering time|short-day photoperiodic control of flowering|response to long-night, flowering|short-day photoperiodic control of inflorescence development|long-night photoperiodism, flowering|response to short-day, flowering													biological_process											owl:Class	
GO:0048573	biolink:NamedThing	photoperiodism, flowering	A change from the vegetative to the reproductive phase as a result of detection of, or exposure to, a period of light or dark of a given length. The length of the period of light or dark required to initiate the change is set relative to a particular duration known as the 'critical day length'. The critical day length varies between species.	tmpzr1t_l9r_go_relaxed.owl	photoperiodic control of flowering time|response to night length, flowering|photoperiodic control of inflorescence development|response to photoperiod, flowering|response to day length, flowering													biological_process											owl:Class	
GO:1902697	biolink:NamedThing	valine catabolic process to isobutanol	The chemical reactions and pathways resulting in the breakdown of valine to isobutanol.	tmpzr1t_l9r_go_relaxed.owl	valine catabolism to isobutanol|valine degradation to isobutanol|valine breakdown to isobutanol							tb	2014-02-19T18:28:19Z			GO:1990292		biological_process											owl:Class	
GO:0006574	biolink:NamedThing	valine catabolic process	The chemical reactions and pathways resulting in the breakdown of valine, 2-amino-3-methylbutanoic acid.	tmpzr1t_l9r_go_relaxed.owl	valine breakdown|valine catabolism|valine degradation				MetaCyc:VALDEG-PWY									biological_process											owl:Class	
GO:1901465	biolink:NamedThing	positive regulation of tetrapyrrole biosynthetic process	Any process that activates or increases the frequency, rate or extent of tetrapyrrole biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	up regulation of tetrapyrrole formation|positive regulation of tetrapyrrole formation|positive regulation of tetrapyrrole anabolism|up regulation of tetrapyrrole biosynthetic process|up-regulation of tetrapyrrole biosynthesis|up-regulation of tetrapyrrole formation|upregulation of tetrapyrrole biosynthetic process|positive regulation of tetrapyrrole synthesis|up regulation of tetrapyrrole synthesis|activation of tetrapyrrole biosynthetic process|up-regulation of tetrapyrrole synthesis|up regulation of tetrapyrrole biosynthesis|upregulation of tetrapyrrole formation|upregulation of tetrapyrrole biosynthesis|up-regulation of tetrapyrrole biosynthetic process|positive regulation of tetrapyrrole biosynthesis|activation of tetrapyrrole biosynthesis|up-regulation of tetrapyrrole anabolism|activation of tetrapyrrole synthesis|upregulation of tetrapyrrole synthesis|activation of tetrapyrrole formation|activation of tetrapyrrole anabolism|up regulation of tetrapyrrole anabolism|upregulation of tetrapyrrole anabolism							tt	2012-10-02T14:35:43Z					biological_process											owl:Class	
GO:0031328	biolink:NamedThing	positive regulation of cellular biosynthetic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances, carried out by individual cells.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of cellular biosynthesis|upregulation of cellular biosynthetic process|positive regulation of cellular anabolism|up-regulation of cellular biosynthetic process|activation of cellular biosynthetic process|up regulation of cellular biosynthetic process|positive regulation of cellular synthesis|stimulation of cellular biosynthetic process|positive regulation of cellular formation													biological_process											owl:Class	
GO:0008614	biolink:NamedThing	pyridoxine metabolic process	The chemical reactions and pathways involving pyridoxine, 2-methyl-3-hydroxy-4,5-bis(hydroxymethyl)pyridine, one of the vitamin B6 compounds. Pyridoxal, pyridoxamine and pyridoxine are collectively known as vitamin B6, and are efficiently converted to the biologically active form of vitamin B6, pyridoxal phosphate.	tmpzr1t_l9r_go_relaxed.owl	pyridoxine metabolism											GO:0006773		biological_process											owl:Class	
GO:1901615	biolink:NamedThing	organic hydroxy compound metabolic process	The chemical reactions and pathways involving organic hydroxy compound.	tmpzr1t_l9r_go_relaxed.owl	organic hydroxy compound metabolism							pr	2012-11-13T12:54:27Z					biological_process											owl:Class	
GO:0060280	biolink:NamedThing	negative regulation of ovulation	Any process that stops, prevents, or reduces the frequency, rate or extent of ovulation, the release of a mature ovum/oocyte from an ovary.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0043915	biolink:NamedThing	L-seryl-tRNA(Sec) kinase activity	Catalysis of the reaction: ATP + L-seryl-tRNA(Sec) = ADP + O-phospho-L-seryl-tRNA(Sec).	tmpzr1t_l9r_go_relaxed.owl	O-phosphoseryl-tRNA(Sec) kinase activity				MetaCyc:RXN-10038|EC:2.7.1.164|RHEA:25037									molecular_function											owl:Class	
GO:0140101	biolink:NamedThing	catalytic activity, acting on a tRNA	Catalytic activity that acts to modify a tRNA.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/14225						pg	2017-09-15T18:41:41Z					molecular_function											owl:Class	
GO:0036138	biolink:NamedThing	peptidyl-histidine hydroxylation	The hydroxylation of peptidyl-histidine to form peptidyl-hydroxyhistidine.	tmpzr1t_l9r_go_relaxed.owl								bf	2012-03-07T09:25:25Z					biological_process											owl:Class	
GO:0018202	biolink:NamedThing	peptidyl-histidine modification	The modification of peptidyl-histidine.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0060760	biolink:NamedThing	positive regulation of response to cytokine stimulus	Any process that increases the rate, frequency, or extent of a response to cytokine stimulus.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-06-22T02:58:04Z					biological_process											owl:Class	
GO:0048584	biolink:NamedThing	positive regulation of response to stimulus	Any process that activates, maintains or increases the rate of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.	tmpzr1t_l9r_go_relaxed.owl	up regulation of response to stimulus|activation of response to stimulus|stimulation of response to stimulus|up-regulation of response to stimulus|upregulation of response to stimulus					Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.								biological_process											owl:Class	
GO:0044630	biolink:NamedThing	modulation of complement activation, lectin pathway in other organism	A process that modulates the frequency, rate or extent of the lectin pathway of complement activation, in a different organism.	tmpzr1t_l9r_go_relaxed.owl	regulation of complement activation, lectin pathway in other organism							jl	2012-07-05T01:10:31Z					biological_process											owl:Class	
GO:0044645	biolink:NamedThing	modulation of complement activation in other organism	A process that modulates the frequency, rate or extent of complement activation in a different organism.	tmpzr1t_l9r_go_relaxed.owl	regulation of complement activation in other organism							jl	2012-07-11T12:37:50Z					biological_process											owl:Class	
GO:1900229	biolink:NamedThing	negative regulation of single-species biofilm formation in or on host organism	Any process that stops, prevents or reduces the frequency, rate or extent of single-species biofilm formation in or on host organism.	tmpzr1t_l9r_go_relaxed.owl	down regulation of single-species biofilm formation in or on host organism|downregulation of single-species biofilm formation in or on host organism|down-regulation of single-species biofilm formation in or on host organism|inhibition of single-species biofilm formation in or on host organism							di	2012-03-23T04:37:05Z					biological_process											owl:Class	
GO:1900228	biolink:NamedThing	regulation of single-species biofilm formation in or on host organism	Any process that modulates the frequency, rate or extent of single-species biofilm formation in or on host organism.	tmpzr1t_l9r_go_relaxed.owl								di	2012-03-23T04:36:54Z					biological_process											owl:Class	
GO:0032301	biolink:NamedThing	MutSalpha complex	A heterodimer involved in the recognition and repair of base-base and small insertion/deletion mismatches. In human the complex consists of two subunits, MSH2 and MSH6.	tmpzr1t_l9r_go_relaxed.owl	MSH2/MSH6 complex|MMR complex													cellular_component											owl:Class	
GO:0140513	biolink:NamedThing	nuclear protein-containing complex	A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together in the nucleus.	tmpzr1t_l9r_go_relaxed.owl	nuclear complex							pg	2020-09-09T05:12:38Z					cellular_component											owl:Class	
GO:1903779	biolink:NamedThing	regulation of cardiac conduction	Any process that modulates the frequency, rate or extent of cardiac conduction.	tmpzr1t_l9r_go_relaxed.owl								rph	2015-01-07T13:20:11Z					biological_process											owl:Class	
GO:1900968	biolink:NamedThing	regulation of sarcinapterin metabolic process	Any process that modulates the frequency, rate or extent of sarcinapterin metabolic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of sarcinapterin metabolism							tt	2012-06-14T03:58:11Z					biological_process											owl:Class	
GO:0062012	biolink:NamedThing	regulation of small molecule metabolic process	Any process that modulates the rate, frequency or extent of a small molecule metabolic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of small molecule metabolism							dph	2018-03-19T14:11:54Z					biological_process											owl:Class	
GO:1902636	biolink:NamedThing	kinociliary basal body	A ciliary basal body that is part of a kinocilium.	tmpzr1t_l9r_go_relaxed.owl	cilial basal body of kinocilium|kinocilium ciliary basal body|ciliary basal body of kinocilium|microtubule basal body of kinocilium|cilium basal body of kinocilium|kinocilium basal body|kinocilial basal body							pr	2014-01-20T13:48:45Z					cellular_component											owl:Class	
GO:0036064	biolink:NamedThing	ciliary basal body	A membrane-tethered, short cylindrical array of microtubules and associated proteins found at the base of a eukaryotic cilium (also called flagellum) that is similar in structure to a centriole and derives from it. The cilium basal body is the site of assembly and remodelling of the cilium and serves as a nucleation site for axoneme growth. As well as anchoring the cilium, it is thought to provide a selective gateway regulating the entry of ciliary proteins and vesicles by intraflagellar transport.	tmpzr1t_l9r_go_relaxed.owl	cilium basal body|basal body|cilial basal body|microtubule basal body|kinetosome				NIF_Subcellular:sao11978067	In most eukaryotic cells, 'ciliary basal body' (GO:0036064) and 'centriole' (GO:0005814) represent a common entity that cycles through its function in cell division, then ciliogenesis, then cell division again. However, these structures are modified extensively as they transition into each other, and may contain different proteins, specific to each component.		bf	2011-12-15T10:40:20Z			GO:0005932		cellular_component											owl:Class	
GO:0033326	biolink:NamedThing	cerebrospinal fluid secretion	The regulated release of cerebrospinal fluid (CSF) from the choroid plexus of the lateral, third and fourth ventricles. The cerebrospinal fluid is a clear liquid that located within the ventricles, spinal canal, and subarachnoid spaces.	tmpzr1t_l9r_go_relaxed.owl	CSF secretion													biological_process											owl:Class	
GO:0007589	biolink:NamedThing	body fluid secretion	The controlled release of a fluid by a cell or tissue in an animal.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0018720	biolink:NamedThing	phenol kinase activity	Catalysis of the reaction: phenol + X-HPO3- = XH + phenylphosphate.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:PHENOLPHOS-RXN|UM-BBD_reactionID:r0155									molecular_function											owl:Class	
GO:0016773	biolink:NamedThing	phosphotransferase activity, alcohol group as acceptor	Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to an alcohol group (acceptor).	tmpzr1t_l9r_go_relaxed.owl					EC:2.7.1.-|Reactome:R-HSA-2161193									molecular_function											owl:Class	
GO:0046907	biolink:NamedThing	intracellular transport	The directed movement of substances within a cell.	tmpzr1t_l9r_go_relaxed.owl	single organism intracellular transport|single-organism intracellular transport							jl	2013-12-18T14:04:50Z			GO:1902582		biological_process											owl:Class	
GO:0051649	biolink:NamedThing	establishment of localization in cell	Any process, occuring in a cell, that localizes a substance or cellular component. This may occur via movement, tethering or selective degradation.	tmpzr1t_l9r_go_relaxed.owl	establishment of cellular localization|positioning within cell|establishment of intracellular localization|establishment of localisation in cell|establishment of localization within cell													biological_process											owl:Class	
GO:0000491	biolink:NamedThing	small nucleolar ribonucleoprotein complex assembly	The aggregation, arrangement and bonding together of proteins and a snoRNA to form a small nucleolar ribonucleoprotein (snoRNP) complex.	tmpzr1t_l9r_go_relaxed.owl	snoRNP assembly													biological_process											owl:Class	
GO:0022618	biolink:NamedThing	ribonucleoprotein complex assembly	The aggregation, arrangement and bonding together of proteins and RNA molecules to form a ribonucleoprotein complex.	tmpzr1t_l9r_go_relaxed.owl	RNA-protein complex assembly|RNP complex assembly|protein-RNA complex assembly													biological_process											owl:Class	
GO:1900884	biolink:NamedThing	regulation of tridecane biosynthetic process	Any process that modulates the frequency, rate or extent of tridecane biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of tridecane synthesis|regulation of tridecane anabolism|regulation of tridecane biosynthesis|regulation of tridecane formation							tt	2012-06-13T03:00:31Z					biological_process											owl:Class	
GO:1900893	biolink:NamedThing	regulation of tridecane metabolic process	Any process that modulates the frequency, rate or extent of tridecane metabolic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of tridecane metabolism							tt	2012-06-13T03:14:40Z					biological_process											owl:Class	
GO:1901314	biolink:NamedThing	regulation of histone H2A K63-linked ubiquitination	Any process that modulates the frequency, rate or extent of histone H2A K63-linked ubiquitination.	tmpzr1t_l9r_go_relaxed.owl								tb	2012-08-22T20:29:04Z					biological_process											owl:Class	
GO:1904481	biolink:NamedThing	response to tetrahydrofolate	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tetrahydrofolate stimulus.	tmpzr1t_l9r_go_relaxed.owl								hal	2015-07-14T14:49:17Z					biological_process											owl:Class	
GO:1901700	biolink:NamedThing	response to oxygen-containing compound	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxygen-containing compound stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to oxygen molecular entity							pr	2012-12-13T15:11:37Z					biological_process											owl:Class	
GO:1905751	biolink:NamedThing	positive regulation of endosome to plasma membrane protein transport	Any process that activates or increases the frequency, rate or extent of endosome to plasma membrane protein transport.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of endosome to plasma membrane protein transport|upregulation of endosome to plasma membrane protein transport|up regulation of endosome to plasma membrane protein transport|activation of endosome to plasma membrane protein transport							pga	2016-12-09T13:46:30Z					biological_process											owl:Class	
GO:1905012	biolink:NamedThing	regulation of 'de novo' NAD biosynthetic process from tryptophan	Any process that modulates the frequency, rate or extent of 'de novo' NAD biosynthetic process from tryptophan.	tmpzr1t_l9r_go_relaxed.owl	regulation of de novo NAD biosynthetic process from tryptophan							bf	2016-03-03T10:00:50Z					biological_process											owl:Class	
GO:0016649	biolink:NamedThing	oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH group acts as a hydrogen or electron donor and reduces quinone or similar compound.	tmpzr1t_l9r_go_relaxed.owl					EC:1.5.5.-									molecular_function											owl:Class	
GO:0016645	biolink:NamedThing	oxidoreductase activity, acting on the CH-NH group of donors	Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.	tmpzr1t_l9r_go_relaxed.owl	oxidoreductase activity, acting on the CH-NH group of donors, other acceptors				EC:1.5.-.-									molecular_function											owl:Class	
GO:0072090	biolink:NamedThing	mesenchymal stem cell proliferation involved in nephron morphogenesis	The multiplication or reproduction of mesenchymal stem cells, resulting in the expansion of a stem cell population, that contributes to the shaping of a nephron.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-02-08T02:05:54Z					biological_process											owl:Class	
GO:0097168	biolink:NamedThing	mesenchymal stem cell proliferation	The multiplication or reproduction of mesenchymal stem cells, resulting in the expansion of a stem cell population. A mesenchymal stem cell, or MSC, is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells.	tmpzr1t_l9r_go_relaxed.owl	MSC proliferation							pr	2011-09-29T04:44:48Z					biological_process											owl:Class	
GO:0033771	biolink:NamedThing	licodione synthase activity	Catalysis of the reaction: H(+) + liquiritigenin + NADPH + O(2) = H(2)O + licodione + NADP(+).	tmpzr1t_l9r_go_relaxed.owl	(2S)-flavanone 2-hydroxylase activity|liquiritigenin,NADPH:oxygen oxidoreductase (licodione-forming) activity				KEGG_REACTION:R07198|MetaCyc:1.14.13.87-RXN|RHEA:15697|EC:1.14.14.140									molecular_function											owl:Class	
GO:0016709	biolink:NamedThing	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen	Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from NADH or NADPH and one other donor, and one atom of oxygen is incorporated into one donor.	tmpzr1t_l9r_go_relaxed.owl	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen				Reactome:R-HSA-2162187|Reactome:R-HSA-2162194|EC:1.14.13.-									molecular_function											owl:Class	
GO:0080190	biolink:NamedThing	lateral growth	Growth of a plant axis (shoot axis or root) that originates from a lateral meristem.	tmpzr1t_l9r_go_relaxed.owl						Includes thickening of plant axes (PO:0025004) due to the activity of a cambium (PO:0005597), known as secondary growth and found in most gymnosperms and dicotyledons, a primary thickening meristem (PO:0005039) as found in many monocotyledons, some ferns and some cycads, or secondary thickening meristem, (PO:0025414) as found in some monocotyledons.		dhl	2012-12-06T15:42:28Z					biological_process											owl:Class	
GO:0040007	biolink:NamedThing	growth	The increase in size or mass of an entire organism, a part of an organism or a cell.	tmpzr1t_l9r_go_relaxed.owl	non-developmental growth|growth pattern					See also the biological process term 'cell growth ; GO:0016049'.						GO:0048590		biological_process											owl:Class	
GO:2000678	biolink:NamedThing	negative regulation of transcription regulatory region DNA binding	Any process that stops, prevents or reduces the frequency, rate or extent of transcription regulatory region DNA binding.	tmpzr1t_l9r_go_relaxed.owl								yaf	2011-05-09T03:28:14Z					biological_process											owl:Class	
GO:0043392	biolink:NamedThing	negative regulation of DNA binding	Any process that stops or reduces the frequency, rate or extent of DNA binding. DNA binding is any process in which a gene product interacts selectively with DNA (deoxyribonucleic acid).	tmpzr1t_l9r_go_relaxed.owl	down-regulation of DNA binding|inhibition of DNA binding|down regulation of DNA binding|downregulation of DNA binding													biological_process											owl:Class	
GO:0002830	biolink:NamedThing	positive regulation of type 2 immune response	Any process that activates or increases the frequency, rate, or extent of a type 2 immune response.	tmpzr1t_l9r_go_relaxed.owl	activation of type 2 immune response|positive regulation of Th2 immune response|up regulation of type 2 immune response|stimulation of type 2 immune response|up-regulation of type 2 immune response|upregulation of type 2 immune response|positive regulation of T-helper 2 type immune response													biological_process											owl:Class	
GO:0002828	biolink:NamedThing	regulation of type 2 immune response	Any process that modulates the frequency, rate, or extent of a type 2 immune response.	tmpzr1t_l9r_go_relaxed.owl	regulation of Th2 immune response|regulation of T-helper 2 type immune response													biological_process											owl:Class	
GO:0017096	biolink:NamedThing	acetylserotonin O-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + N-acetylserotonin = S-adenosyl-L-homocysteine + melatonin. Melatonin is also known as N-acetyl-5-methoxytryptamine.	tmpzr1t_l9r_go_relaxed.owl	S-adenosyl-L-methionine:N-acetylserotonin O-methyltransferase activity|N-acetylserotonin O-methyltransferase activity|acetylserotonin methyltransferase activity|hydroxyindole O-methyltransferase activity|hydroxyindole methyltransferase activity				EC:2.1.1.4|MetaCyc:ACETYLSEROTONIN-O-METHYLTRANSFERASE-RXN|RHEA:15573							GO:0017097		molecular_function											owl:Class	
GO:0060053	biolink:NamedThing	neurofilament cytoskeleton	Intermediate filament cytoskeletal structure that is made up of neurofilaments. Neurofilaments are specialized intermediate filaments found in neurons.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0045111	biolink:NamedThing	intermediate filament cytoskeleton	Cytoskeletal structure made from intermediate filaments, typically organized in the cytosol as an extended system that stretches from the nuclear envelope to the plasma membrane. Some intermediate filaments run parallel to the cell surface, while others traverse the cytosol; together they form an internal framework that helps support the shape and resilience of the cell.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0045621	biolink:NamedThing	positive regulation of lymphocyte differentiation	Any process that activates or increases the frequency, rate or extent of lymphocyte differentiation.	tmpzr1t_l9r_go_relaxed.owl	up regulation of lymphocyte differentiation|up-regulation of lymphocyte differentiation|upregulation of lymphocyte differentiation|positive regulation of lymphocyte development|stimulation of lymphocyte differentiation|activation of lymphocyte differentiation					Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.								biological_process											owl:Class	
GO:0045619	biolink:NamedThing	regulation of lymphocyte differentiation	Any process that modulates the frequency, rate or extent of lymphocyte differentiation.	tmpzr1t_l9r_go_relaxed.owl	regulation of lymphocyte development					Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.								biological_process											owl:Class	
GO:1905412	biolink:NamedThing	negative regulation of mitotic cohesin loading	Any process that stops, prevents or reduces the frequency, rate or extent of mitotic cohesin loading.	tmpzr1t_l9r_go_relaxed.owl								vw	2016-08-27T15:24:35Z					biological_process											owl:Class	
GO:0090519	biolink:NamedThing	anoxia protection	Any process in which an organism or cell protects itself from anoxia, which may also result in resistance to repeated exposure to anoxia.	tmpzr1t_l9r_go_relaxed.owl								tb	2012-12-21T15:37:37Z					biological_process											owl:Class	
GO:0034059	biolink:NamedThing	response to anoxia	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating a decline in oxygen levels to trace amounts, <0.1%.	tmpzr1t_l9r_go_relaxed.owl	response to anoxic stress					Note that this term should not be confused with 'response to hypoxia ; GO:0001666'.								biological_process											owl:Class	
GO:0048766	biolink:NamedThing	root hair initiation	The process in which a protrusion or bulge is formed at the site of plant root hair outgrowth.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0000904	biolink:NamedThing	cell morphogenesis involved in differentiation	The change in form (cell shape and size) that occurs when relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0031438	biolink:NamedThing	negative regulation of mRNA cleavage	Any process that stops, prevents, or reduces the frequency, rate or extent of mRNA cleavage.	tmpzr1t_l9r_go_relaxed.owl	downregulation of mRNA cleavage|down-regulation of mRNA cleavage|down regulation of mRNA cleavage|inhibition of mRNA cleavage													biological_process											owl:Class	
GO:0010243	biolink:NamedThing	response to organonitrogen compound	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organonitrogen stimulus. An organonitrogen compound is formally a compound containing at least one carbon-nitrogen bond.	tmpzr1t_l9r_go_relaxed.owl	response to organic nitrogen													biological_process											owl:Class	
GO:0010033	biolink:NamedThing	response to organic substance	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic substance stimulus.	tmpzr1t_l9r_go_relaxed.owl	process resulting in tolerance to organic substance											GO:1990367		biological_process											owl:Class	
GO:0030211	biolink:NamedThing	heparin catabolic process	The chemical reactions and pathways resulting in the breakdown of heparin, any member of a group of glycosaminoglycans of average Mr (6000-20000), consisting predominantly of alternating alpha-(1->4)-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues.	tmpzr1t_l9r_go_relaxed.owl	heparan sulfate catabolic process|heparin breakdown|heparin catabolism|heparin degradation													biological_process											owl:Class	
GO:0030202	biolink:NamedThing	heparin metabolic process	The chemical reactions and pathways involving heparin, any member of a group of glycosaminoglycans found mainly as an intracellular component of mast cells. They are similar to heparan sulfates but are of somewhat higher average Mr (6000-20000) and contain fewer N-acetyl groups and more N-sulfate and O-sulfate groups; they may be attached in the same manner to protein, forming proteoglycans. They consist predominantly of alternating alpha-(1->4)-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues.	tmpzr1t_l9r_go_relaxed.owl	heparin metabolism|heparan sulfate metabolic process													biological_process											owl:Class	
GO:1903687	biolink:NamedThing	negative regulation of border follicle cell migration	Any process that stops, prevents or reduces the frequency, rate or extent of border follicle cell migration.	tmpzr1t_l9r_go_relaxed.owl	inhibition of border follicle cell migration							als	2014-12-01T13:41:05Z					biological_process											owl:Class	
GO:0034040	biolink:NamedThing	ATPase-coupled lipid transmembrane transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + lipid(in) = ADP + phosphate + lipid(out).	tmpzr1t_l9r_go_relaxed.owl	ATP-dependent lipid transmembrane transporter activity|lipid-transporting ATPase activity													molecular_function											owl:Class	
GO:0042626	biolink:NamedThing	ATPase-coupled transmembrane transporter activity	Primary active transporter of a solute across a membrane, via the reaction: ATP + H2O = ADP + phosphate, to directly drive the transport of a substance across a membrane. The transport protein may be transiently phosphorylated (P-type transporters), or not (ABC-type transporters and other families of transporters). Primary active transport occurs up the solute's concentration gradient and is driven by a primary energy source.	tmpzr1t_l9r_go_relaxed.owl	P-P-bond-hydrolysis-driven transmembrane transporter activity|hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances|ATP-coupled transmembrane transporter activity|ATP-dependent transmembrane transporter activity|ATPase activity, coupled to transmembrane movement of substances|P-P-bond-hydrolysis-driven transporter|ATPase activity, coupled to movement of substances	https://github.com/geneontology/go-ontology/issues/19965|https://github.com/geneontology/go-ontology/issues/17373|https://github.com/geneontology/go-ontology/issues/14642			Reactome:R-HSA-2161538|Reactome:R-HSA-1467457|Reactome:R-HSA-9033505|Reactome:R-HSA-9033499|Reactome:R-HSA-2161506							GO:0043492|GO:0016820|GO:0015405		molecular_function											owl:Class	
GO:0032377	biolink:NamedThing	regulation of intracellular lipid transport	Any process that modulates the frequency, rate or extent of the directed movement of lipids within cells.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0032368	biolink:NamedThing	regulation of lipid transport	Any process that modulates the frequency, rate or extent of the directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0045856	biolink:NamedThing	positive regulation of pole plasm oskar mRNA localization	Any process that activates or increases the frequency, rate or extent of the process in which oskar mRNA is transported to, or maintained in, the oocyte pole plasm.	tmpzr1t_l9r_go_relaxed.owl	activation of pole plasm oskar mRNA localization|positive regulation of pole plasm oskar mRNA localisation|positive regulation of oocyte pole plasm oskar mRNA localization|upregulation of pole plasm oskar mRNA localization|stimulation of pole plasm oskar mRNA localization|up regulation of pole plasm oskar mRNA localization|up-regulation of pole plasm oskar mRNA localization													biological_process											owl:Class	
GO:1905695	biolink:NamedThing	positive regulation of phosphatidic acid biosynthetic process	Any process that activates or increases the frequency, rate or extent of phosphatidic acid biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	up regulation of phosphatidic acid anabolism|up-regulation of phosphatidic acid synthesis|upregulation of phosphatidic acid formation|activation of phosphatidic acid formation|activation of phosphatidic acid anabolism|upregulation of phosphatidic acid synthesis|up regulation of phosphatidic acid biosynthetic process|up regulation of phosphatidic acid formation|up-regulation of phosphatidic acid formation|activation of phosphatidic acid biosynthesis|up-regulation of phosphatidic acid biosynthesis|up-regulation of phosphatidic acid biosynthetic process|activation of phosphatidic acid synthesis|up regulation of phosphatidic acid synthesis|activation of phosphatidic acid biosynthetic process|upregulation of phosphatidic acid biosynthetic process|up regulation of phosphatidic acid biosynthesis|positive regulation of phosphatidic acid formation|upregulation of phosphatidic acid anabolism|up-regulation of phosphatidic acid anabolism|positive regulation of phosphatidic acid synthesis|positive regulation of phosphatidic acid anabolism|positive regulation of phosphatidic acid biosynthesis|upregulation of phosphatidic acid biosynthesis							bc	2016-11-14T14:48:24Z					biological_process											owl:Class	
GO:0071073	biolink:NamedThing	positive regulation of phospholipid biosynthetic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of phospholipids.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of phospholipid biosynthesis|up regulation of phospholipid biosynthetic process|positive regulation of phospholipid anabolism|stimulation of phospholipid biosynthetic process|upregulation of phospholipid biosynthetic process|activation of phospholipid biosynthetic process|positive regulation of phospholipid synthesis|positive regulation of phospholipid formation|up-regulation of phospholipid biosynthetic process							mah	2009-11-04T03:18:51Z					biological_process											owl:Class	
GO:0062156	biolink:NamedThing	mitochondrial ATP-gated potassium channel activity	Enables the ATP-dependent diffusion of a potassium ion across the mitochondrial inner membrane.	tmpzr1t_l9r_go_relaxed.owl	mitoK-ATP activity|mitochondrial potassium channel activity							dph	2019-09-20T16:07:07Z					molecular_function											owl:Class	
GO:0099094	biolink:NamedThing	ligand-gated cation channel activity	Enables the transmembrane transfer of an inorganic cation by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0035500	biolink:NamedThing	MH2 domain binding	Binding to a MH2 (MAD homology 2) protein domain. The MH2 domain is found at the carboxy-terminus of MAD related proteins such as Smads. The MH2 domain mediates interaction with a wide variety of proteins and provides specificity and selectivity to Smad function and also is critical for mediating interactions in Smad oligomers.	tmpzr1t_l9r_go_relaxed.owl	MAD homology 2 domain binding							bf	2010-04-29T03:14:32Z					molecular_function											owl:Class	
GO:0019904	biolink:NamedThing	protein domain specific binding	Binding to a specific domain of a protein.	tmpzr1t_l9r_go_relaxed.owl	protein domain-specific binding													molecular_function											owl:Class	
GO:0032981	biolink:NamedThing	mitochondrial respiratory chain complex I assembly	The aggregation, arrangement and bonding together of a set of components to form mitochondrial respiratory chain complex I.	tmpzr1t_l9r_go_relaxed.owl	mitochondrial NADH dehydrogenase complex (ubiquinone) assembly|mitochondrial complex I assembly													biological_process											owl:Class	
GO:0033108	biolink:NamedThing	mitochondrial respiratory chain complex assembly	The aggregation, arrangement and bonding together of a set of components to form a mitochondrial respiratory chain complex.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0009059	biolink:NamedThing	macromolecule biosynthetic process	The chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.	tmpzr1t_l9r_go_relaxed.owl	macromolecule anabolism|macromolecule formation|macromolecule biosynthesis|macromolecule synthesis|biopolymer biosynthetic process											GO:0043284		biological_process											owl:Class	
GO:0043170	biolink:NamedThing	macromolecule metabolic process	The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.	tmpzr1t_l9r_go_relaxed.owl	multicellular organismal macromolecule metabolic process|organismal macromolecule metabolism|macromolecule metabolism|biopolymer metabolic process											GO:0043283|GO:0044259		biological_process											owl:Class	
GO:0004658	biolink:NamedThing	propionyl-CoA carboxylase activity	Catalysis of the reaction: ATP + propanoyl-CoA + HCO3- = ADP + phosphate + (S)-methylmalonyl-CoA.	tmpzr1t_l9r_go_relaxed.owl	PCCase activity|propionyl coenzyme A carboxylase activity|propanoyl-CoA:carbon-dioxide ligase (ADP-forming)				EC:6.4.1.3|MetaCyc:PROPIONYL-COA-CARBOXY-RXN|Reactome:R-HSA-71031|RHEA:23720									molecular_function											owl:Class	
GO:0016421	biolink:NamedThing	CoA carboxylase activity	Catalysis of the joining of a carboxyl group to a molecule that is attached to CoA, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:2000281	biolink:NamedThing	regulation of histone H3-T3 phosphorylation	Any process that modulates the frequency, rate or extent of histone H3-T3 phosphorylation.	tmpzr1t_l9r_go_relaxed.owl								vw	2010-12-10T11:48:31Z					biological_process											owl:Class	
GO:1903702	biolink:NamedThing	esophagus development	The process whose specific outcome is the progression of an esophagus over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl	esophageal development|oesophagus development|gullet development							cls	2014-12-03T14:41:30Z					biological_process											owl:Class	
GO:0048513	biolink:NamedThing	animal organ development	Development of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.	tmpzr1t_l9r_go_relaxed.owl	organogenesis|development of an organ				Wikipedia:Organogenesis									biological_process											owl:Class	
GO:2000700	biolink:NamedThing	positive regulation of cardiac muscle cell myoblast differentiation	Any process that activates or increases the frequency, rate or extent of cardiac muscle cell myoblast differentiation.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of cardiac myoblast differentiation|positive regulation of myocardial precursor cell differentiation							yaf	2011-05-25T09:08:09Z					biological_process											owl:Class	
GO:0045663	biolink:NamedThing	positive regulation of myoblast differentiation	Any process that activates or increases the frequency, rate or extent of myoblast differentiation. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.	tmpzr1t_l9r_go_relaxed.owl	upregulation of myoblast differentiation|activation of myoblast differentiation|stimulation of myoblast differentiation|up regulation of myoblast differentiation|up-regulation of myoblast differentiation													biological_process											owl:Class	
GO:0006967	biolink:NamedThing	positive regulation of antifungal peptide biosynthetic process	Any process that activates or increases the frequency, rate, or extent of antifungal peptide biosynthesis.	tmpzr1t_l9r_go_relaxed.owl	antifungal peptide induction|activation of antifungal peptide biosynthetic process|up-regulation of antifungal peptide biosynthetic process|antifungal polypeptide induction|upregulation of antifungal peptide biosynthetic process|stimulation of antifungal peptide biosynthetic process|up regulation of antifungal peptide biosynthetic process													biological_process											owl:Class	
GO:0002807	biolink:NamedThing	positive regulation of antimicrobial peptide biosynthetic process	Any process that activates or increases the frequency, rate, or extent of antimicrobial peptide biosynthesis.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of antimicrobial peptide biosynthetic process|stimulation of antimicrobial peptide biosynthetic process|upregulation of antimicrobial peptide biosynthetic process|activation of antimicrobial peptide biosynthetic process|up regulation of antimicrobial peptide biosynthetic process													biological_process											owl:Class	
GO:0000749	biolink:NamedThing	response to pheromone triggering conjugation with cellular fusion	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pheromone stimulus that positively regulates the process of conjugation with cellular fusion. An example of this process is found in Saccharomyces cerevisiae.	tmpzr1t_l9r_go_relaxed.owl	response to pheromone during conjugation with cellular fusion											GO:0030434|GO:0007328		biological_process											owl:Class	
GO:0019236	biolink:NamedThing	response to pheromone	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pheromone stimulus.	tmpzr1t_l9r_go_relaxed.owl	pheromone response													biological_process											owl:Class	
GO:0017148	biolink:NamedThing	negative regulation of translation	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of protein synthesis|negative regulation of protein biosynthetic process|down regulation of protein biosynthetic process|negative regulation of protein anabolism|inhibition of protein biosynthetic process|protein biosynthetic process inhibitor activity|downregulation of protein biosynthetic process|negative regulation of protein formation|down-regulation of protein biosynthetic process|protein biosynthesis inhibitor activity|negative regulation of protein biosynthesis											GO:0016478		biological_process											owl:Class	
GO:0006417	biolink:NamedThing	regulation of translation	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA.	tmpzr1t_l9r_go_relaxed.owl	regulation of protein anabolism|regulation of protein biosynthesis|regulation of protein synthesis|regulation of protein formation											GO:0006445		biological_process											owl:Class	
GO:0051009	biolink:NamedThing	O-acetylhomoserine sulfhydrylase activity	Catalysis of the reaction: O-acetyl-L-homoserine + hydrogen sulfide = homocysteine + acetate.	tmpzr1t_l9r_go_relaxed.owl					RHEA:27822|MetaCyc:ACETYLHOMOSER-CYS-RXN									molecular_function											owl:Class	
GO:0016835	biolink:NamedThing	carbon-oxygen lyase activity	Catalysis of the breakage of a carbon-oxygen bond.	tmpzr1t_l9r_go_relaxed.owl	other carbon-oxygen lyase activity				EC:4.2.-.-									molecular_function											owl:Class	
GO:1990354	biolink:NamedThing	activated SUMO-E1 ligase complex	A protein complex consisting of a SUMO protein bound to a SUMO activating enzyme complex. Activation by the E1 complex and linkage to the E2 enzyme UBE2I is required for the formation of covalent bonds between SUMO and its ultimate target proteins.	tmpzr1t_l9r_go_relaxed.owl	SUMO-SAE1/2 complex					An example of this is SAE1 in human (UniProt symbol Q9UBE0) in PMID:15660128 (inferred from direct assay).		bhm	2014-03-31T13:22:45Z					cellular_component											owl:Class	
GO:0106068	biolink:NamedThing	SUMO ligase complex	A protein ligase complex that enables protein sumoylation. Consists of a SUMO-protein transferase and other proteins that may confer substrate specificity of the complex.	tmpzr1t_l9r_go_relaxed.owl	SUMO-protein ligase complex|Sumoylation complex|SUMO transferase complex							hjd	2017-11-22T18:46:00Z					cellular_component											owl:Class	
GO:0015179	biolink:NamedThing	L-amino acid transmembrane transporter activity	Enables the transfer of an L-amino acid from one side of a membrane to the other. L-amino acids are the L-enantiomers of amino acids.	tmpzr1t_l9r_go_relaxed.owl	L-amino acid transporter activity				Reactome:R-HSA-212614									molecular_function											owl:Class	
GO:0015171	biolink:NamedThing	amino acid transmembrane transporter activity	Enables the transfer of amino acids from one side of a membrane to the other. Amino acids are organic molecules that contain an amino group and a carboxyl group.	tmpzr1t_l9r_go_relaxed.owl	general amino acid permease activity|amino acid/choline transmembrane transporter activity|amino acid transporter activity|amino acid permease activity|hydroxy/aromatic amino acid permease activity				Reactome:R-HSA-379415|Reactome:R-HSA-351963|Reactome:R-HSA-352379|Reactome:R-HSA-352103|Reactome:R-HSA-5660694|Reactome:R-HSA-375776|Reactome:R-HSA-352347|Reactome:R-HSA-352136|Reactome:R-HSA-352119|Reactome:R-HSA-352371|Reactome:R-HSA-5653850|Reactome:R-HSA-5660890|Reactome:R-HSA-352158|Reactome:R-HSA-375487|Reactome:R-HSA-376200|Reactome:R-HSA-352108|Reactome:R-HSA-352174|Reactome:R-HSA-888592|Reactome:R-HSA-352385|Reactome:R-HSA-352107|Reactome:R-HSA-352059|Reactome:R-HSA-5655702|Reactome:R-HSA-375417|Reactome:R-HSA-5660910|Reactome:R-HSA-5659674|Reactome:R-HSA-210439|Reactome:R-HSA-352364|Reactome:R-HSA-212642|Reactome:R-HSA-352354|Reactome:R-HSA-379432|Reactome:R-HSA-375768|Reactome:R-HSA-375770|Reactome:R-HSA-375473|Reactome:R-HSA-8952726|Reactome:R-HSA-379426|Reactome:R-HSA-5659755|Reactome:R-HSA-375405|Reactome:R-HSA-352029|Reactome:R-HSA-351987|Reactome:R-HSA-352191|Reactome:R-HSA-352052|Reactome:R-HSA-5659734|Reactome:R-HSA-375790|Reactome:R-HSA-352232|Reactome:R-HSA-352182|Reactome:R-HSA-378513							GO:0015359		molecular_function											owl:Class	
GO:0052587	biolink:NamedThing	diacetyl reductase ((R)-acetoin forming) activity	Catalysis of the reaction: (R)-acetoin + NAD(+) = diacetyl + H(+) + NADH.	tmpzr1t_l9r_go_relaxed.owl	(R)-acetoin dehydrogenase activity				MetaCyc:RXN-11036|KEGG_REACTION:R02855|EC:1.1.1.303|RHEA:22900									molecular_function											owl:Class	
GO:0019152	biolink:NamedThing	acetoin dehydrogenase activity	Catalysis of the reaction: acetoin + NAD+ = diacetyl + NADH + H+.	tmpzr1t_l9r_go_relaxed.owl	diacetyl reductase activity				EC:1.1.1.304|MetaCyc:ACETOINDEHYDROG-RXN|EC:1.1.1.303|KEGG_REACTION:R02343									molecular_function											owl:Class	
GO:1902939	biolink:NamedThing	negative regulation of intracellular calcium activated chloride channel activity	Any process that stops, prevents or reduces the frequency, rate or extent of intracellular calcium activated chloride channel activity.	tmpzr1t_l9r_go_relaxed.owl	down regulation of intracellular calcium activated chloride channel activity|inhibition of intracellular calcium activated chloride channel activity|down-regulation of intracellular calcium activated chloride channel activity|downregulation of intracellular calcium activated chloride channel activity							als	2014-04-28T08:49:14Z					biological_process											owl:Class	
GO:0008046	biolink:NamedThing	axon guidance receptor activity	Combining with an extracellular messenger and transmitting the signal from one side of the membrane to the other to results in a change in cellular activity involved in axon guidance.	tmpzr1t_l9r_go_relaxed.owl	receptor activity involved in axon guidance													molecular_function											owl:Class	
GO:0004888	biolink:NamedThing	transmembrane signaling receptor activity	Combining with an extracellular or intracellular signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity or state as part of signal transduction.	tmpzr1t_l9r_go_relaxed.owl	transmembrane signalling receptor activity|transmembrane receptor activity				Reactome:R-HSA-193672	This term includes intracellular membrane receptors, e.g. IP3 triggered release of Ca2+ from intracellular stores.						GO:0004926|GO:0099600		molecular_function											owl:Class	
GO:0002205	biolink:NamedThing	somatic hypermutation of immunoglobulin genes involved in immune response	Mutations occurring somatically that result in amino acid changes in the rearranged V regions of immunoglobulins following the induction of and contributing to an immune response.	tmpzr1t_l9r_go_relaxed.owl	somatic hypermutation of antibody genes during immune response|somatic hypermutation of immunoglobulin genes during immune response													biological_process											owl:Class	
GO:0002208	biolink:NamedThing	somatic diversification of immunoglobulins involved in immune response	The somatic process that results in the generation of sequence diversity of immunoglobulins after induction, and contributes to an immune response.	tmpzr1t_l9r_go_relaxed.owl	somatic diversification of immunoglobulins during immune response|somatic diversification of antibodies during immune response													biological_process											owl:Class	
GO:0003368	biolink:NamedThing	cell-matrix adhesion involved in mesendodermal cell migration	The binding of a cell to the extracellular matrix that contributes to the directed movement of a mesendodermal cell.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-12-08T05:26:12Z					biological_process											owl:Class	
GO:0007160	biolink:NamedThing	cell-matrix adhesion	The binding of a cell to the extracellular matrix via adhesion molecules.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0030263	biolink:NamedThing	apoptotic chromosome condensation	The compaction of chromatin during apoptosis.	tmpzr1t_l9r_go_relaxed.owl	pyknosis				Wikipedia:Pyknosis									biological_process											owl:Class	
GO:0030261	biolink:NamedThing	chromosome condensation	The progressive compaction of dispersed interphase chromatin into threadlike chromosomes prior to mitotic or meiotic nuclear division, or during apoptosis, in eukaryotic cells.	tmpzr1t_l9r_go_relaxed.owl	eukaryotic chromosome condensation|DNA condensation|nuclear chromosome condensation											GO:0000068		biological_process											owl:Class	
GO:0042996	biolink:NamedThing	regulation of Golgi to plasma membrane protein transport	Any process that modulates the frequency, rate or extent of the transport of proteins from the Golgi to the plasma membrane.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1903076	biolink:NamedThing	regulation of protein localization to plasma membrane	Any process that modulates the frequency, rate or extent of protein localization to plasma membrane.	tmpzr1t_l9r_go_relaxed.owl	regulation of establishment of protein localization to plasma membrane|regulation of protein targeting to plasma membrane|regulation of establishment of protein localization in plasma membrane|regulation of establishment of protein localisation in plasma membrane|regulation of protein-plasma membrane targeting|regulation of protein localization in plasma membrane|regulation of protein localisation in plasma membrane							tb	2009-07-10T10:32:44Z			GO:1905963|GO:0090003		biological_process											owl:Class	
GO:0060556	biolink:NamedThing	regulation of vitamin D biosynthetic process	Any process that modulates the rate frequency or extent of a vitamin D biosynthetic process. Vitamin D biosynthesis is the chemical reactions and pathways resulting in the formation of vitamin D, any of a group of related, fat-soluble compounds that are derived from delta-5,7 steroids and play a central role in calcium metabolism. Specific forms of vitamin D include calciferol (ergocalciferol; vitamin D2) and cholecalciferol (calciol; vitamin D3).	tmpzr1t_l9r_go_relaxed.owl								dph	2009-04-13T02:42:15Z					biological_process											owl:Class	
GO:0031326	biolink:NamedThing	regulation of cellular biosynthetic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances, carried out by individual cells.	tmpzr1t_l9r_go_relaxed.owl	regulation of cellular biosynthesis|regulation of cellular synthesis|regulation of cellular formation|regulation of cellular anabolism													biological_process											owl:Class	
GO:1904318	biolink:NamedThing	regulation of smooth muscle contraction involved in micturition	Any process that modulates the frequency, rate or extent of smooth muscle contraction involved in micturition.	tmpzr1t_l9r_go_relaxed.owl	regulation of urinary bladder smooth muscle contraction involved in micturition|regulation of smooth muscle contraction involved in urination							sl	2015-06-10T18:46:11Z					biological_process											owl:Class	
GO:0006940	biolink:NamedThing	regulation of smooth muscle contraction	Any process that modulates the frequency, rate or extent of smooth muscle contraction.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0018034	biolink:NamedThing	C-terminal peptidyl-alanine amidation	The formation of a C-terminal peptidyl-alanine amide by hydrolysis and oxidation of an interior Ala-Gly peptide in a secreted protein.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0081									biological_process											owl:Class	
GO:0018194	biolink:NamedThing	peptidyl-alanine modification	The modification of peptidyl-alanine.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0021829	biolink:NamedThing	oligodendrocyte cell migration from the subpallium to the cortex	The directed movement of oligodendrocytes from the subpallium to the cerebral cortex during forebrain development.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0022030	biolink:NamedThing	telencephalon glial cell migration	The orderly movement of glial cells through the telencephalon.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0036203	biolink:NamedThing	taxoid 14-beta-hydroxylase activity	Catalysis of the reaction: 10beta-hydroxytaxa-4(20),11-dien-5alpha-yl acetate + O2 + NADPH + H+ = 10beta,14beta-dihydroxytaxa-4(20),11-dien-5alpha-yl acetate + NADP+ + H2O.	tmpzr1t_l9r_go_relaxed.owl					KEGG_REACTION:R09867|RHEA:31971|EC:1.14.13.146			bf	2012-04-20T02:40:54Z					molecular_function											owl:Class	
GO:0032059	biolink:NamedThing	bleb	A cell extension caused by localized decoupling of the cytoskeleton from the plasma membrane and characterized by rapid formation, rounded shape, and scarcity of organelles within the protrusion. Blebs are formed during apoptosis and other cellular processes, including cell locomotion, cell division, and as a result of physical or chemical stresses.	tmpzr1t_l9r_go_relaxed.owl	plasma membrane bleb				Wikipedia:Bleb_(cell_biology)									cellular_component											owl:Class	
GO:0120025	biolink:NamedThing	plasma membrane bounded cell projection	A prolongation or process extending from a cell and that is bounded by plasma membrane, e.g. a cilium, lamellipodium, or axon.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/13193						krc	2017-03-21T17:26:07Z					cellular_component											owl:Class	
GO:0018247	biolink:NamedThing	protein-phosphoribosyl dephospho-coenzyme A linkage	The linkage of phosphoribosyl dephospho-coenzyme A to protein via peptidyl-serine, to form O-(phosphoribosyl dephospho-coenzyme A)-L-serine; it is uncertain whether the phosphoribosyl glycosidic attachment to the dephospho-coenzyme A is alpha or beta, and through the 2' or the 3' position.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0167									biological_process											owl:Class	
GO:0018246	biolink:NamedThing	protein-coenzyme A linkage	The formation of a linkage between a protein amino acid and coenzyme A.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0031896	biolink:NamedThing	V2 vasopressin receptor binding	Binding to a V2 vasopressin receptor.	tmpzr1t_l9r_go_relaxed.owl	V2 vasopressin receptor ligand													molecular_function											owl:Class	
GO:0031893	biolink:NamedThing	vasopressin receptor binding	Binding to a vasopressin receptor.	tmpzr1t_l9r_go_relaxed.owl	vasopressin receptor ligand													molecular_function											owl:Class	
GO:1900918	biolink:NamedThing	negative regulation of octadecene metabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of octadecene metabolic process.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of octadecene metabolism|downregulation of octadecene metabolism|down regulation of octadecene metabolism|down-regulation of octadecene metabolism|inhibition of octadecene metabolic process|down regulation of octadecene metabolic process|downregulation of octadecene metabolic process|inhibition of octadecene metabolism|down-regulation of octadecene metabolic process							tt	2012-06-13T04:26:34Z					biological_process											owl:Class	
GO:1990826	biolink:NamedThing	nucleoplasmic periphery of the nuclear pore complex	Nucleoplasm situated in close proximity and peripheral to a nuclear pore complex.	tmpzr1t_l9r_go_relaxed.owl	associated with the nuclear pore	https://github.com/geneontology/go-ontology/issues/21774						sl	2015-08-19T18:26:26Z					cellular_component											owl:Class	
GO:0045290	biolink:NamedThing	D-arabinose 1-dehydrogenase [NAD(P)+] activity	Catalysis of the reaction: D-arabinose + NAD(P)+ = D-arabinono-1,4-lactone + NAD(P)H + H+.	tmpzr1t_l9r_go_relaxed.owl	D-arabinose:NAD(P)+ 1-oxidoreductase activity				EC:1.1.1.117|MetaCyc:1.1.1.117-RXN									molecular_function											owl:Class	
GO:0016616	biolink:NamedThing	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces NAD+ or NADP.	tmpzr1t_l9r_go_relaxed.owl	NADH-dependent glyoxylate reductase|glycolate reductase|glyoxylic acid reductase				EC:1.1.1.-|Reactome:R-HSA-975629									molecular_function											owl:Class	
GO:0019271	biolink:NamedThing	aerobactin transport	The directed movement of the hydroxamate iron transport compound aerobactin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Aerobactin (C22H36N4O13) is a conjugate of 6-(N-acetyl-N-hydroxylamine)-2-aminohexanoic acid and citric acid.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0072337	biolink:NamedThing	modified amino acid transport	The directed movement of modified amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	amino acid derivative transport							mah	2010-11-04T12:18:23Z					biological_process											owl:Class	
GO:0061359	biolink:NamedThing	regulation of Wnt signaling pathway by Wnt protein secretion	Any process that modulates the frequency, rate or extent of the activity of the Wnt signaling pathway by the controlled release of a Wnt protein from a cell.	tmpzr1t_l9r_go_relaxed.owl	regulation of Wnt-activated signaling pathway by Wnt protein secretion|regulation of Wnt receptor signalling pathway by Wnt protein secretion|regulation of Wnt receptor signaling pathway by Wnt protein secretion							dph	2010-10-08T01:18:02Z					biological_process											owl:Class	
GO:0061355	biolink:NamedThing	Wnt protein secretion	The controlled release of a Wnt protein from a cell.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-10-08T01:07:48Z					biological_process											owl:Class	
GO:0002855	biolink:NamedThing	regulation of natural killer cell mediated immune response to tumor cell	Any process that modulates the frequency, rate, or extent of natural killer cell mediated immune response to a tumor cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0002715	biolink:NamedThing	regulation of natural killer cell mediated immunity	Any process that modulates the frequency, rate, or extent of natural killer cell mediated immunity.	tmpzr1t_l9r_go_relaxed.owl	regulation of NK cell mediated immunity|regulation of natural killer cell activity											GO:0045845		biological_process											owl:Class	
GO:0008878	biolink:NamedThing	glucose-1-phosphate adenylyltransferase activity	Catalysis of the reaction: alpha-D-glucose 1-phosphate + ATP = ADP-glucose + diphosphate.	tmpzr1t_l9r_go_relaxed.owl	ADP-glucose pyrophosphorylase activity|glucose 1-phosphate adenylyltransferase activity|ADP-glucose synthetase activity|ATP:alpha-D-glucose-1-phosphate adenylyltransferase activity|ADGase activity|ATP:alpha-glucose-1-phosphate adenylyl transferase activity|adenosine diphosphoglucose pyrophosphorylase activity|adenosine diphosphate glucose pyrophosphorylase activity|ADP-glucose diphosphorylase activity|ADP-glucose synthase activity|ADP:alpha-D-glucose-1-phosphate adenylyltransferase activity|ADP glucose pyrophosphorylase activity|ADPG pyrophosphorylase activity				EC:2.7.7.27|RHEA:12120|MetaCyc:GLUC1PADENYLTRANS-RXN|KEGG_REACTION:R00948									molecular_function											owl:Class	
GO:0070566	biolink:NamedThing	adenylyltransferase activity	Catalysis of the transfer of an adenylyl group to an acceptor.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-04-15T11:04:22Z					molecular_function											owl:Class	
GO:0006760	biolink:NamedThing	folic acid-containing compound metabolic process	The chemical reactions and pathways involving a folic acid-containing compound, i.e. any of a group of heterocyclic compounds based on the pteroic acid skeleton conjugated with one or more L-glutamic acid or L-glutamate units.	tmpzr1t_l9r_go_relaxed.owl	folate and derivative metabolic process|vitamin M and derivative metabolic process|vitamin B9 and derivative metabolism|vitamin M and derivative metabolism|folic acid-containing compound metabolism|folate and derivative metabolism|folic acid and derivative metabolism|folic acid and derivative metabolic process|vitamin B9 and derivative metabolic process|folate-containing compound metabolic process|folate-containing compound metabolism													biological_process											owl:Class	
GO:0042558	biolink:NamedThing	pteridine-containing compound metabolic process	The chemical reactions and pathways involving any compound containing pteridine (pyrazino(2,3-dipyrimidine)), e.g. pteroic acid, xanthopterin and folic acid.	tmpzr1t_l9r_go_relaxed.owl	pterin metabolic process|pteridine-containing compound metabolism|pteridine and derivative metabolism|pteridine and derivative metabolic process|pterin metabolism											GO:0019721		biological_process											owl:Class	
GO:0061299	biolink:NamedThing	retina vasculature morphogenesis in camera-type eye	The process in which the vasculature of the retina is generated and organized.	tmpzr1t_l9r_go_relaxed.owl	retinal vasculature morphogenesis							dph	2010-09-06T03:28:25Z					biological_process											owl:Class	
GO:0009653	biolink:NamedThing	anatomical structure morphogenesis	The process in which anatomical structures are generated and organized. Morphogenesis pertains to the creation of form.	tmpzr1t_l9r_go_relaxed.owl	embryogenesis and morphogenesis|anatomical structure organization|morphogenesis				Wikipedia:Morphogenesis									biological_process											owl:Class	
GO:2001171	biolink:NamedThing	positive regulation of ATP biosynthetic process	Any process that activates or increases the frequency, rate or extent of ATP biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of ATP formation|positive regulation of ATP synthesis|positive regulation of ATP biosynthesis|positive regulation of ATP regeneration|positive regulation of ATP anabolism							kmv	2011-10-26T03:18:26Z					biological_process											owl:Class	
GO:0072594	biolink:NamedThing	establishment of protein localization to organelle	The directed movement of a protein to a specific location on or in an organelle. Encompasses establishment of localization in the membrane or lumen of a membrane-bounded organelle.	tmpzr1t_l9r_go_relaxed.owl	establishment of protein localisation to organelle							mah	2011-02-14T01:56:51Z					biological_process											owl:Class	
GO:0045184	biolink:NamedThing	establishment of protein localization	The directed movement of a protein to a specific location.	tmpzr1t_l9r_go_relaxed.owl	protein positioning|establishment of protein localisation|protein recruitment													biological_process											owl:Class	
GO:0120233	biolink:NamedThing	prenyl-FMNH2 binding	Binding to prenyl-FMNH2, a flavin mononucleotide obtained by prenylation of the N-10 position of FMNH2 followed by cyclisation. An essential cofactor for the decarboxylase enzymes UbiD and Fdc1.	tmpzr1t_l9r_go_relaxed.owl	prenylated FMNH2 binding	https://github.com/geneontology/go-ontology/issues/19244						krc	2020-06-30T19:32:01Z					molecular_function											owl:Class	
GO:0043168	biolink:NamedThing	anion binding	Binding to an anion, a charged atom or group of atoms with a net negative charge.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0090338	biolink:NamedThing	positive regulation of formin-nucleated actin cable assembly	Any process that increases the rate, frequency, or extent of formin-nucleated actin cable assembly. Formin-nucleated actin cable assembly is the aggregation, arrangement and bonding together of a set of components to form a formin-nucleated actin cable. A formin-nucleated actin cable is an actin filament bundle that consists of short filaments organized into bundles of uniform polarity, and is nucleated by formins.	tmpzr1t_l9r_go_relaxed.owl								tb	2010-06-01T03:26:31Z					biological_process											owl:Class	
GO:0032233	biolink:NamedThing	positive regulation of actin filament bundle assembly	Any process that activates or increases the frequency, rate or extent of the assembly of actin filament bundles.	tmpzr1t_l9r_go_relaxed.owl	upregulation of actin filament bundle formation|activation of actin filament bundle formation|stimulation of actin filament bundle formation|up regulation of actin filament bundle formation|up-regulation of actin filament bundle formation													biological_process											owl:Class	
GO:0006554	biolink:NamedThing	lysine catabolic process	The chemical reactions and pathways resulting in the breakdown of lysine, 2,6-diaminohexanoic acid.	tmpzr1t_l9r_go_relaxed.owl	lysine degradation|lysine breakdown|lysine catabolism													biological_process											owl:Class	
GO:0009063	biolink:NamedThing	cellular amino acid catabolic process	The chemical reactions and pathways resulting in the breakdown of amino acids, organic acids containing one or more amino substituents.	tmpzr1t_l9r_go_relaxed.owl	cellular amino acid breakdown|cellular amino acid catabolism|cellular amino acid degradation|amino acid catabolic process													biological_process											owl:Class	
GO:0070478	biolink:NamedThing	nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay	The chemical reactions and pathways resulting in the breakdown of the nuclear-transcribed mRNA transcript body of an mRNA in which an amino-acid codon has changed to a nonsense codon; occurs when the 3' end is not protected by a 3'-poly(A) tail; degradation proceeds in the 3' to 5' direction.	tmpzr1t_l9r_go_relaxed.owl	3'-5' nonsense-mediated decay|3'-5' nonsense-mediated mRNA decay|nuclear-transcribed mRNA breakdown, 3'-5' exonucleolytic nonsense-mediated decay|nuclear-transcribed mRNA degradation, 3'-5' exonucleolytic nonsense-mediated decay|3'-5' NMD|nuclear-transcribed mRNA catabolism, 3'-5' exonucleolytic nonsense-mediated decay													biological_process											owl:Class	
GO:0034427	biolink:NamedThing	nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'	The chemical reactions and pathways resulting in the breakdown of the mRNA transcript body that occurs when the 3' end is not protected by a 3'-poly(A) tail; degradation proceeds in the 3' to 5' direction.	tmpzr1t_l9r_go_relaxed.owl	3'-5' exonucleolytic nuclear-transcribed mRNA catabolic process													biological_process											owl:Class	
GO:0014059	biolink:NamedThing	regulation of dopamine secretion	Any process that modulates the frequency, rate or extent of the regulated release of dopamine.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0043269	biolink:NamedThing	regulation of ion transport	Any process that modulates the frequency, rate or extent of the directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0097635	biolink:NamedThing	extrinsic component of autophagosome membrane	The component of the autophagosome membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.	tmpzr1t_l9r_go_relaxed.owl	extrinsic component of autophagic vacuole membrane|extrinsic to autophagic vacuole membrane|autophagic vacuole peripheral membrane													cellular_component											owl:Class	
GO:0019898	biolink:NamedThing	extrinsic component of membrane	The component of a membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.	tmpzr1t_l9r_go_relaxed.owl	extrinsic to membrane|peripheral membrane protein				Wikipedia:Peripheral_membrane_protein	Note that proteins extrinsic to membranes can be removed by treatments that do not disrupt the membrane, such as salt solutions.						GO:0030396		cellular_component											owl:Class	
GO:1904240	biolink:NamedThing	negative regulation of VCP-NPL4-UFD1 AAA ATPase complex assembly	Any process that stops, prevents or reduces the frequency, rate or extent of VCP-NPL4-UFD1 AAA ATPase complex assembly.	tmpzr1t_l9r_go_relaxed.owl	down regulation of VCP-NPL4-UFD1 AAA ATPase complex formation|negative regulation of Cdc48p-Npl4p-Ufd1p AAA ATPase complex formation|down-regulation of p97-Ufd1-Npl4 complex assembly|inhibition of p97-Ufd1-Npl4 complex assembly|down-regulation of VCP-NPL4-UFD1 AAA ATPase complex formation|down regulation of Cdc48p-Npl4p-Ufd1p AAA ATPase complex formation|downregulation of Cdc48p-Npl4p-Ufd1p AAA ATPase complex assembly|negative regulation of p97-Ufd1-Npl4 complex formation|down-regulation of Cdc48p-Npl4p-Ufd1p AAA ATPase complex assembly|down regulation of p97-Ufd1-Npl4 complex formation|negative regulation of VCP-NPL4-UFD1 AAA ATPase complex formation|downregulation of VCP-NPL4-UFD1 AAA ATPase complex formation|downregulation of p97-Ufd1-Npl4 complex assembly|downregulation of Cdc48p-Npl4p-Ufd1p AAA ATPase complex formation|downregulation of p97-Ufd1-Npl4 complex formation|inhibition of Cdc48p-Npl4p-Ufd1p AAA ATPase complex assembly|negative regulation of Cdc48p-Npl4p-Ufd1p AAA ATPase complex assembly|negative regulation of p97-Ufd1-Npl4 complex assembly|down regulation of Cdc48p-Npl4p-Ufd1p AAA ATPase complex assembly|downregulation of VCP-NPL4-UFD1 AAA ATPase complex assembly|down regulation of p97-Ufd1-Npl4 complex assembly|down-regulation of p97-Ufd1-Npl4 complex formation|inhibition of VCP-NPL4-UFD1 AAA ATPase complex assembly|down regulation of VCP-NPL4-UFD1 AAA ATPase complex assembly|inhibition of Cdc48p-Npl4p-Ufd1p AAA ATPase complex formation|down-regulation of Cdc48p-Npl4p-Ufd1p AAA ATPase complex formation|inhibition of p97-Ufd1-Npl4 complex formation|down-regulation of VCP-NPL4-UFD1 AAA ATPase complex assembly|inhibition of VCP-NPL4-UFD1 AAA ATPase complex formation							bf	2015-05-18T09:50:27Z					biological_process											owl:Class	
GO:0031333	biolink:NamedThing	negative regulation of protein-containing complex assembly	Any process that stops, prevents, or reduces the frequency, rate or extent of protein complex assembly.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of protein complex assembly|downregulation of protein complex assembly|down regulation of protein complex assembly|inhibition of protein complex assembly|negative regulation of protein complex assembly													biological_process											owl:Class	
GO:0070689	biolink:NamedThing	L-threonine catabolic process to propionate	The chemical reactions and pathways resulting in the breakdown of L-threonine (the L-enantiomer of 2-amino-3-hydroxybutyric acid) to form the compound propionate.	tmpzr1t_l9r_go_relaxed.owl	L-threonine catabolism to propionate|L-threonine breakdown to propionate|threonine catabolic process to propionate|L-threonine degradation to propionate				MetaCyc:PWY-5437			mah	2009-06-03T01:36:54Z					biological_process											owl:Class	
GO:0006567	biolink:NamedThing	threonine catabolic process	The chemical reactions and pathways resulting in the breakdown of threonine (2-amino-3-hydroxybutyric acid), a polar, uncharged, essential amino acid found in peptide linkage in proteins.	tmpzr1t_l9r_go_relaxed.owl	threonine catabolism|threonine breakdown|threonine degradation				UM-BBD_pathwayID:met|MetaCyc:THREOCAT-PWY									biological_process											owl:Class	
GO:1901625	biolink:NamedThing	cellular response to ergosterol	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ergosterol stimulus.	tmpzr1t_l9r_go_relaxed.owl								dph	2012-11-14T13:53:51Z					biological_process											owl:Class	
GO:0036315	biolink:NamedThing	cellular response to sterol	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sterol stimulus.	tmpzr1t_l9r_go_relaxed.owl								bf	2012-08-21T14:51:21Z					biological_process											owl:Class	
GO:1904683	biolink:NamedThing	regulation of metalloendopeptidase activity	Any process that modulates the frequency, rate or extent of metalloendopeptidase activity.	tmpzr1t_l9r_go_relaxed.owl	regulation of metalloendoproteinase activity|regulation of metalloendoprotease activity							rph	2015-09-24T11:18:14Z					biological_process											owl:Class	
GO:1905048	biolink:NamedThing	regulation of metallopeptidase activity	Any process that modulates the frequency, rate or extent of metallopeptidase activity.	tmpzr1t_l9r_go_relaxed.owl	regulation of metalloproteinase activity|regulation of metalloprotease activity							mm2	2016-03-15T16:44:27Z					biological_process											owl:Class	
GO:1905263	biolink:NamedThing	positive regulation of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination	Any process that activates or increases the frequency, rate or extent of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination.	tmpzr1t_l9r_go_relaxed.owl	up regulation of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination|up-regulation of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination|upregulation of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination|activation of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination							se	2016-06-13T20:45:18Z					biological_process											owl:Class	
GO:0035426	biolink:NamedThing	extracellular matrix-cell signaling	Any process that mediates the transfer of information between the extracellular matrix and a cell.	tmpzr1t_l9r_go_relaxed.owl	cell-extracellular matrix signalling|extracellular matrix-cell signalling							bf	2010-03-29T02:26:54Z					biological_process											owl:Class	
GO:0023052	biolink:NamedThing	signaling	The entirety of a process in which information is transmitted within a biological system. This process begins with an active signal and ends when a cellular response has been triggered.	tmpzr1t_l9r_go_relaxed.owl	signalling|signalling process|single organism signaling|signaling process|biological signaling					Note that a signal is any variable property or parameter that serves to convey information, and may be a physical entity such as a gene product or small molecule, a photon, or a change in state such as movement or voltage change.		jl	2010-02-16T09:30:50Z			GO:0044700|GO:0023046		biological_process											owl:Class	
GO:0090394	biolink:NamedThing	negative regulation of excitatory postsynaptic potential	Any process that prevents the establishment or decreases the extent of the excitatory postsynaptic potential (EPSP) which is a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC) and makes it easier for the neuron to fire an action potential.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of EPSP|negative regulation of excitatory post-synaptic membrane potential|reduction of excitatory postsynaptic membrane potential							tb	2010-12-15T01:43:12Z					biological_process											owl:Class	
GO:0098815	biolink:NamedThing	modulation of excitatory postsynaptic potential	Any process that modulates the frequency, rate or extent of excitatory postsynaptic potential (EPSP). EPSP is a process that leads to a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC) and makes it easier for the neuron to fire an action potential.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1902647	biolink:NamedThing	negative regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	inhibition of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process|down-regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate anabolism|downregulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process|downregulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate anabolism|negative regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate synthesis|negative regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthesis|downregulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthesis|downregulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate formation|inhibition of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate formation|down-regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process|down regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthesis|downregulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate synthesis|down-regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate synthesis|negative regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate formation|inhibition of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate anabolism|down regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate synthesis|inhibition of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthesis|down regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate anabolism|negative regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate anabolism|down regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process|down regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate formation|down-regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate formation|inhibition of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate synthesis|down-regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthesis							di	2014-01-21T17:58:06Z					biological_process											owl:Class	
GO:0010512	biolink:NamedThing	negative regulation of phosphatidylinositol biosynthetic process	Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of phosphatidylinositol.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0001919	biolink:NamedThing	regulation of receptor recycling	Any process that modulates the frequency, rate, or extent of receptor recycling.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0031323	biolink:NamedThing	regulation of cellular metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances.	tmpzr1t_l9r_go_relaxed.owl	regulation of cellular metabolism													biological_process											owl:Class	
GO:0003325	biolink:NamedThing	pancreatic PP cell development	The process whose specific outcome is the progression of a pancreatic PP cell over time, from its formation to the mature structure. A pancreatic polypeptide-producing cell is a cell in the pancreas that produces pancreatic polypeptide.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-11-02T08:25:03Z					biological_process											owl:Class	
GO:0002068	biolink:NamedThing	glandular epithelial cell development	The process whose specific outcome is the progression of a glandular epithelial cell over time, from its formation to the mature structure. A glandular epithelial cell is a columnar/cuboidal epithelial cell is a cell found in a two dimensional sheet with a free surface exposed to the lumen of a gland.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0007312	biolink:NamedThing	oocyte nucleus migration involved in oocyte dorsal/ventral axis specification	The directed movement of the oocyte nucleus within the cell as part of the establishment and maintenance of the dorsal/ventral axis of the oocyte. An example of this is found in Drosophila melanogaster.	tmpzr1t_l9r_go_relaxed.owl	establishment of oocyte nucleus localization involved in oocyte dorsal-ventral axis specification|oocyte nucleus positioning during oocyte axis determination|oocyte axis determination, establishment of localization of nucleus|establishment of oocyte nucleus localization during oocyte axis determination|oocyte nucleus migration during oocyte axis determination|oocyte nuclear migration during oocyte axis determination|establishment of oocyte nucleus localization involved in oocyte dorsal/ventral axis specification|oocyte nucleus migration during oocyte axis specification|oocyte axis determination, oocyte nucleus migration|oocyte axis determination, establishment of position of nucleus|oocyte axis determination, establishment of oocyte nucleus localization|establishment of oocyte nucleus localization involved in oocyte dorsal/ventral axis determination|nucleus positioning in oocyte during oocyte axis determination|establishment of oocyte nucleus localisation involved in oocyte dorsal/ventral axis specification|oocyte axis determination, oocyte nuclear migration|establishment of oocyte nucleus localization involved in oocyte dorsoventral axis specification|oocyte axis determination, positioning of nucleus|establishment of localization of oocyte nucleus during oocyte axis determination											GO:0048128|GO:0030722|GO:0048126|GO:0008102		biological_process											owl:Class	
GO:0007097	biolink:NamedThing	nuclear migration	The directed movement of the nucleus to a specific location within a cell.	tmpzr1t_l9r_go_relaxed.owl	establishment of position of nucleus|nucleus positioning|nucleus migration|nuclear positioning|positioning of nucleus|establishment of localization of nucleus|establishment of nucleus localization|nuclear movement|establishment of nucleus localisation|establishment of cell nucleus localization											GO:0040023		biological_process											owl:Class	
GO:0034134	biolink:NamedThing	toll-like receptor 2 signaling pathway	Any series of molecular signals generated as a consequence of binding to toll-like receptor 2.	tmpzr1t_l9r_go_relaxed.owl	toll-like receptor 2 signalling pathway|TLR2 signaling pathway													biological_process											owl:Class	
GO:0002224	biolink:NamedThing	toll-like receptor signaling pathway	Any series of molecular signals generated as a consequence of binding to a toll-like receptor. Toll-like receptors directly bind pattern motifs from a variety of microbial sources to initiate innate immune response.	tmpzr1t_l9r_go_relaxed.owl	TLR signaling pathway|toll-like receptor signalling pathway					Note that the vertebrate toll-like receptors, unlike the Drosophila Toll molecule, directly bind their ligands. The Drosophila Toll molecule requires the Sptzle factor to bind microbial ligands and then the receptor in order to initiate innate immune responses.								biological_process											owl:Class	
GO:0012511	biolink:NamedThing	monolayer-surrounded lipid storage body	A subcellular organelle of plant cells surrounded by 'half-unit' or a monolayer membrane instead of the more usual bilayer. The storage body has a droplet of triglyceride surrounded by a monolayer of phospholipids, interacting with the triglycerides and the hydrophilic head groups facing the cytosol, and containing major protein components called oleosins.	tmpzr1t_l9r_go_relaxed.owl	oleosome|oilbody|spherosome|oil body				Wikipedia:Oil_body							GO:0009520		cellular_component											owl:Class	
GO:0005811	biolink:NamedThing	lipid droplet	An intracellular non-membrane-bounded organelle comprising a matrix of coalesced lipids surrounded by a phospholipid monolayer. May include associated proteins.	tmpzr1t_l9r_go_relaxed.owl	lipid particle|lipid body|adiposome					Note that this term does not refer to vesicles, but instead to structures in which lipids do not necessarily form bilayers.								cellular_component											owl:Class	
GO:0046112	biolink:NamedThing	nucleobase biosynthetic process	The chemical reactions and pathways resulting in the formation of a nucleobase, a nitrogenous base that is a constituent of a nucleic acid.	tmpzr1t_l9r_go_relaxed.owl	nucleobase synthesis|nucleobase biosynthesis|nucleobase formation|nucleobase anabolism													biological_process											owl:Class	
GO:0018130	biolink:NamedThing	heterocycle biosynthetic process	The chemical reactions and pathways resulting in the formation of heterocyclic compounds, those with a cyclic molecular structure and at least two different atoms in the ring (or rings).	tmpzr1t_l9r_go_relaxed.owl	heterocycle formation|heterocycle biosynthesis|heterocycle anabolism|heterocycle synthesis													biological_process											owl:Class	
GO:0102910	biolink:NamedThing	dirigent protein activity	Catalysis of the reaction: 2 H+ + 2 coniferol + O2 <=> (+)-pinoresinol + 2 H2O.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-8677									molecular_function											owl:Class	
GO:0016682	biolink:NamedThing	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which a diphenol, or related compound, acts as a hydrogen or electron donor and reduces oxygen.	tmpzr1t_l9r_go_relaxed.owl	laccase activity				EC:1.10.3.-									molecular_function											owl:Class	
GO:0032147	biolink:NamedThing	activation of protein kinase activity	Any process that initiates the activity of an inactive protein kinase.	tmpzr1t_l9r_go_relaxed.owl	protein kinase activation													biological_process											owl:Class	
GO:0045860	biolink:NamedThing	positive regulation of protein kinase activity	Any process that activates or increases the frequency, rate or extent of protein kinase activity.	tmpzr1t_l9r_go_relaxed.owl	stimulation of protein kinase activity|up-regulation of protein kinase activity|up regulation of protein kinase activity|upregulation of protein kinase activity													biological_process											owl:Class	
GO:0050560	biolink:NamedThing	aspartate-tRNA(Asn) ligase activity	Catalysis of the reaction: tRNA(Asx) + L-aspartate + ATP = aspartyl-tRNA(Asx) + diphosphate + AMP.	tmpzr1t_l9r_go_relaxed.owl	aspartate-tRNAAsn ligase activity|L-aspartate:tRNAAsx ligase (AMP-forming)|nondiscriminating aspartyl-tRNA synthetase activity				EC:6.1.1.23|MetaCyc:6.1.1.23-RXN|RHEA:18349									molecular_function											owl:Class	
GO:0004812	biolink:NamedThing	aminoacyl-tRNA ligase activity	Catalysis of the formation of aminoacyl-tRNA from ATP, amino acid, and tRNA with the release of diphosphate and AMP.	tmpzr1t_l9r_go_relaxed.owl	aminoacyl-tRNA synthetase auxiliary protein activity|ligase activity, forming aminoacyl-tRNA and related compounds|aminoacyl-tRNA synthetase activity				EC:6.1.1.-	Note that the bond resulting from this reaction is a carboxylic acid ester bond, linking the alpha carboxyl group of the amino acid to either the 2' or 3' hydroxyl of the 3'- terminal adenyl residue of the tRNA.						GO:0017100|GO:0016876		molecular_function											owl:Class	
GO:0062238	biolink:NamedThing	Smp focus	A DNA-binding ribonucleoprotein complex that contains a lncRNA complementary to the bound chromosomal locus and is involved in the tethering homologous chromosomes together during chromosome pairing at meiotic prophase I.	tmpzr1t_l9r_go_relaxed.owl	Smp dot							dph	2020-04-20T14:23:04Z					cellular_component											owl:Class	
GO:1990904	biolink:NamedThing	ribonucleoprotein complex	A macromolecular complex that contains both RNA and protein molecules.	tmpzr1t_l9r_go_relaxed.owl	intracellular ribonucleoprotein complex|extracellular ribonucleoprotein complex|RNA-protein complex|protein-RNA complex|RNP				Wikipedia:Ribonucleoprotein			pr	2015-11-19T12:26:37Z			GO:0030529|GO:1990903		cellular_component											owl:Class	
GO:0099640	biolink:NamedThing	axo-dendritic protein transport	The directed movement of proteins along microtubules in neuron projections.	tmpzr1t_l9r_go_relaxed.owl	axonal protein transport													biological_process											owl:Class	
GO:0008088	biolink:NamedThing	axo-dendritic transport	The directed movement of organelles or molecules along microtubules in neuron projections.	tmpzr1t_l9r_go_relaxed.owl	axonal transport|axoplasmic transport|axon cargo transport				Wikipedia:Axoplasmic_transport									biological_process											owl:Class	
GO:2000399	biolink:NamedThing	negative regulation of thymocyte aggregation	Any process that stops, prevents or reduces the frequency, rate or extent of thymocyte aggregation.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of immature T cell aggregation|negative regulation of immature T-lymphocyte aggregation|negative regulation of T cell precursor aggregation|negative regulation of thymic lymphocyte aggregation|negative regulation of immature T-cell aggregation							mah	2011-02-22T02:49:44Z					biological_process											owl:Class	
GO:0098882	biolink:NamedThing	structural constituent of presynaptic active zone	The action of a molecule that contributes to the structural integrity of a presynaptic active zone.	tmpzr1t_l9r_go_relaxed.owl	structural constituent of active zone													molecular_function											owl:Class	
GO:0005198	biolink:NamedThing	structural molecule activity	The action of a molecule that contributes to the structural integrity of a complex or its assembly within or outside a cell.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0019651	biolink:NamedThing	citrate catabolic process to diacetyl	The anaerobic chemical reactions and pathways resulting in the breakdown of citrate to diacetyl, yielding energy in the form of ATP.	tmpzr1t_l9r_go_relaxed.owl	diacetyl fermentation|citrate fermentation to diacetyl													biological_process											owl:Class	
GO:0019662	biolink:NamedThing	non-glycolytic fermentation	Fermentation that does not include the anaerobic conversion of glucose to pyruvate via the glycolytic pathway.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0015350	biolink:NamedThing	methotrexate transmembrane transporter activity	Enables the transfer of methotrexate, 4-amino-10-methylformic acid from one side of a membrane to the other. Methotrexate is a folic acid analogue and a potent competitive inhibitor of dihydrofolate reductase.	tmpzr1t_l9r_go_relaxed.owl	methotrexate transporter activity													molecular_function											owl:Class	
GO:0008514	biolink:NamedThing	organic anion transmembrane transporter activity	Enables the transfer of organic anions from one side of a membrane to the other. Organic anions are atoms or small molecules with a negative charge which contain carbon in covalent linkage.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-2142859									molecular_function											owl:Class	
GO:2000027	biolink:NamedThing	regulation of animal organ morphogenesis	Any process that modulates the frequency, rate or extent of animal organ morphogenesis.	tmpzr1t_l9r_go_relaxed.owl	regulation of histogenesis and organogenesis							tb	2010-08-05T11:26:27Z					biological_process											owl:Class	
GO:0010359	biolink:NamedThing	regulation of anion channel activity	Any process that modulates the frequency, rate or extent of anion channel activity.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1903959	biolink:NamedThing	regulation of anion transmembrane transport	Any process that modulates the frequency, rate or extent of anion transmembrane transport.	tmpzr1t_l9r_go_relaxed.owl								pr	2015-02-25T13:52:25Z					biological_process											owl:Class	
GO:0060078	biolink:NamedThing	regulation of postsynaptic membrane potential	Any process that modulates the potential difference across a post-synaptic membrane.	tmpzr1t_l9r_go_relaxed.owl	regulation of post-synaptic membrane potential													biological_process											owl:Class	
GO:0042391	biolink:NamedThing	regulation of membrane potential	Any process that modulates the establishment or extent of a membrane potential, the electric potential existing across any membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0045729	biolink:NamedThing	respiratory burst at fertilization	The phase of elevated metabolic activity, during which oxygen consumption increases, that occurs at fertilization. An enhanced uptake of oxygen leads to the production of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals. Capacitation, a necessary prerequisite event to successful fertilization, can be induced by reactive oxygen species in vitro; hydrogen peroxide is used as an extracellular oxidant to cross-link the protective surface envelopes.	tmpzr1t_l9r_go_relaxed.owl	metabolic burst at fertilization|oxidative burst at fertilization													biological_process											owl:Class	
GO:0045730	biolink:NamedThing	respiratory burst	A phase of elevated metabolic activity, during which oxygen consumption increases; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals.	tmpzr1t_l9r_go_relaxed.owl	oxidative burst|metabolic burst				Wikipedia:Respiratory_burst									biological_process											owl:Class	
GO:0061720	biolink:NamedThing	6-sulfoquinovose(1-) catabolic process to glycerone phosphate and 3-sulfolactaldehyde	The chemical reactions and pathways resulting in the breakdown of 6-sulfoquinovose(1-) resulting in the formation of glycerone phosphate (DHAP) and 3-sulfolactaldehyde (SLA).	tmpzr1t_l9r_go_relaxed.owl								dph	2015-07-01T08:47:30Z					biological_process											owl:Class	
GO:1902777	biolink:NamedThing	6-sulfoquinovose(1-) catabolic process	The chemical reactions and pathways resulting in the breakdown of 6-sulfoquinovose(1-).	tmpzr1t_l9r_go_relaxed.owl	6-sulfoquinovose(1-) breakdown|6-sulfoquinovose(1-) degradation|6-sulfoquinovose(1-) catabolism							dph	2014-03-18T17:46:03Z					biological_process											owl:Class	
GO:0097340	biolink:NamedThing	inhibition of cysteine-type endopeptidase activity	Any process that prevents the activation of an inactive cysteine-type endopeptidase.	tmpzr1t_l9r_go_relaxed.owl	prevention of caspase activity|inhibition of caspase activity|prevention of cysteine-type endopeptidase activity							pr	2012-06-18T11:23:05Z					biological_process											owl:Class	
GO:0097341	biolink:NamedThing	zymogen inhibition	Any process that prevents the proteolytic processing of an inactive enzyme to an active form.	tmpzr1t_l9r_go_relaxed.owl	prevention of zymogen activation							pr	2012-06-18T11:25:45Z					biological_process											owl:Class	
GO:0000480	biolink:NamedThing	endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	Endonucleolytic cleavage within the 5'-External Transcribed Spacer (ETS) of a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, the 5.8S rRNA, and the Large Subunit (LSU) rRNA in that order from 5' to 3' along the primary transcript. Endonucleolytic cleavage within the 5'-ETS of the pre-RNA is conserved as one of the early steps of rRNA processing in all eukaryotes, but the specific position of cleavage is variable.	tmpzr1t_l9r_go_relaxed.owl	endonucleolytic cleavage at A0|endonucleolytic cleavage at A-prime													biological_process											owl:Class	
GO:0000479	biolink:NamedThing	endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	Endonucleolytic cleavage of a pre-rRNA molecule originally produced as a tricistronic rRNA transcript that contains the Small SubUnit (SSU) rRNA, the 5.8S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript. Primary ribosomal RNA transcripts with three genes, in this order, are produced in the nuclei of many eukaryotic species, including S. cerevisiae.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0090549	biolink:NamedThing	response to carbon starvation	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of a carbon source.	tmpzr1t_l9r_go_relaxed.owl								tb	2013-04-22T13:57:16Z					biological_process											owl:Class	
GO:0042594	biolink:NamedThing	response to starvation	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of nourishment.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0090696	biolink:NamedThing	post-embryonic plant organ development	Development, taking place during the post-embryonic phase of a plant tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.	tmpzr1t_l9r_go_relaxed.owl								tb	2016-08-25T16:35:55Z					biological_process											owl:Class	
GO:0009791	biolink:NamedThing	post-embryonic development	The process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure. See embryonic development.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0035206	biolink:NamedThing	regulation of hemocyte proliferation	Any process that modulates the frequency, rate or extent of hemocyte proliferation. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. An example of this is found in Drosophila melanogaster.	tmpzr1t_l9r_go_relaxed.owl	regulation of arthropod blood cell proliferation													biological_process											owl:Class	
GO:0042127	biolink:NamedThing	regulation of cell population proliferation	Any process that modulates the frequency, rate or extent of cell proliferation.	tmpzr1t_l9r_go_relaxed.owl	regulation of cell proliferation													biological_process											owl:Class	
GO:0042317	biolink:NamedThing	penicillin catabolic process	The chemical reactions and pathways resulting in the breakdown of any antibiotic that contains the condensed beta-lactamthiazolidine ring system.	tmpzr1t_l9r_go_relaxed.owl	penicillin catabolism|penicillin degradation|penicillin breakdown													biological_process											owl:Class	
GO:0030655	biolink:NamedThing	beta-lactam antibiotic catabolic process	The chemical reactions and pathways resulting in the breakdown of a beta-lactam antibiotic, any member of a class of natural or semisynthetic antibiotics whose characteristic feature is a strained, four-membered beta-lactam ring. They include the penicillins and many of the cephalosporins.	tmpzr1t_l9r_go_relaxed.owl	beta-lactam antibiotic breakdown|beta-lactam antibiotic degradation|beta-lactam antibiotic catabolism													biological_process											owl:Class	
GO:0048093	biolink:NamedThing	positive regulation of male pigmentation	Any process that activates or increases the frequency, rate or extent of establishment of a pattern of pigment in males.	tmpzr1t_l9r_go_relaxed.owl	activation of male pigmentation|stimulation of male pigmentation|up-regulation of male pigmentation|up regulation of male pigmentation|upregulation of male pigmentation													biological_process											owl:Class	
GO:0048087	biolink:NamedThing	positive regulation of developmental pigmentation	Any process that increases the frequency, rate or extent of the developmental process that results in the deposition of coloring matter in an organism.	tmpzr1t_l9r_go_relaxed.owl	upregulation of developmental pigmentation|activation of developmental pigmentation|up regulation of developmental pigmentation|stimulation of developmental pigmentation|up-regulation of developmental pigmentation													biological_process											owl:Class	
GO:0030886	biolink:NamedThing	negative regulation of myeloid dendritic cell activation	Any process that stops, prevents, or reduces the frequency, rate or extent of myeloid dendritic cell activation.	tmpzr1t_l9r_go_relaxed.owl	inhibition of myeloid dendritic cell activation|downregulation of myeloid dendritic cell activation|down regulation of myeloid dendritic cell activation|down-regulation of myeloid dendritic cell activation													biological_process											owl:Class	
GO:0050077	biolink:NamedThing	maleylpyruvate isomerase activity	Catalysis of the reaction: 3-maleylpyruvate = 3-fumarylpyruvate.	tmpzr1t_l9r_go_relaxed.owl	3-maleylpyruvate cis-trans-isomerase activity				EC:5.2.1.4|MetaCyc:MALEYLPYRUVATE-ISOMERASE-RXN|RHEA:17393									molecular_function											owl:Class	
GO:0016859	biolink:NamedThing	cis-trans isomerase activity	Catalysis of a reaction that interconverts cis and trans isomers. Atoms or groups are termed cis or trans to one another when they lie respectively on the same or on opposite sides of a reference plane identifiable as common among stereoisomers.	tmpzr1t_l9r_go_relaxed.owl					EC:5.2.-.-									molecular_function											owl:Class	
GO:0006662	biolink:NamedThing	glycerol ether metabolic process	The chemical reactions and pathways involving glycerol ethers, any anhydride formed between two organic hydroxy compounds, one of which is glycerol.	tmpzr1t_l9r_go_relaxed.owl	glycerol ether metabolism													biological_process											owl:Class	
GO:0018904	biolink:NamedThing	ether metabolic process	The chemical reactions and pathways involving organic ethers, any anhydride of the general formula R1-O-R2, formed between two identical or nonidentical organic hydroxy compounds.	tmpzr1t_l9r_go_relaxed.owl	organic ether metabolic process|organic ether metabolism|ether metabolism													biological_process											owl:Class	
GO:0002455	biolink:NamedThing	humoral immune response mediated by circulating immunoglobulin	An immune response dependent upon secreted immunoglobulin. An example of this process is found in Mus musculus.	tmpzr1t_l9r_go_relaxed.owl	humoral defence mechanism|circulating immunoglobulin mediated immune response|circulating antibody mediated immune response|humoral immune response mediated by circulating antibody													biological_process											owl:Class	
GO:0006959	biolink:NamedThing	humoral immune response	An immune response mediated through a body fluid.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Humoral_immunity									biological_process											owl:Class	
GO:0140214	biolink:NamedThing	positive regulation of long-chain fatty acid import into cell	Any process that activates or increases the frequency, rate or extent of long-chain fatty acid import into a cell.	tmpzr1t_l9r_go_relaxed.owl								pg	2018-04-10T15:15:03Z					biological_process											owl:Class	
GO:2000193	biolink:NamedThing	positive regulation of fatty acid transport	Any process that activates or increases the frequency, rate or extent of fatty acid transport.	tmpzr1t_l9r_go_relaxed.owl								rl	2010-10-18T10:37:17Z					biological_process											owl:Class	
GO:2000248	biolink:NamedThing	negative regulation of establishment or maintenance of neuroblast polarity	Any process that stops, prevents, or reduces the frequency, rate or extent of establishment or maintenance of neuroblast polarity.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of establishment and/or maintenance of neuroblast cell polarity							vw	2010-11-11T11:40:34Z					biological_process											owl:Class	
GO:0034488	biolink:NamedThing	basic amino acid transmembrane export from vacuole	The directed movement of basic amino acids out of the vacuole, across the vacuolar membrane.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1990822	biolink:NamedThing	basic amino acid transmembrane transport	The directed movement of basic amino acids from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl								vw	2015-08-19T07:47:00Z					biological_process											owl:Class	
GO:0008115	biolink:NamedThing	sarcosine oxidase activity	Catalysis of the reaction: H(2)O + O(2) + sarcosine = formaldehyde + glycine + H(2)O(2).	tmpzr1t_l9r_go_relaxed.owl	sarcosine:oxygen oxidoreductase (demethylating)				KEGG_REACTION:R00610|EC:1.5.3.1|RHEA:13313|MetaCyc:SARCOX-RXN									molecular_function											owl:Class	
GO:0016647	biolink:NamedThing	oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH group acts as a hydrogen or electron donor and reduces oxygen.	tmpzr1t_l9r_go_relaxed.owl					EC:1.5.3.-									molecular_function											owl:Class	
GO:0052150	biolink:NamedThing	modulation by symbiont of host apoptotic process	Any process in which an organism modulates the frequency, rate or extent of programmed cell death in the host, where programmed cell death proceeds by apoptosis. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	modulation by organism of host apoptotic programmed cell death|modulation by symbiont of host apoptosis					Note that term is to be used to annotate gene products in the symbiont. To annotate host gene products, consider the biological process term 'regulation of apoptosis ; GO:0042981'.								biological_process											owl:Class	
GO:0042981	biolink:NamedThing	regulation of apoptotic process	Any process that modulates the occurrence or rate of cell death by apoptotic process.	tmpzr1t_l9r_go_relaxed.owl	apoptosis regulator activity|regulation of apoptosis					This term should only be used when it is not possible to determine which phase or subtype of the apoptotic process is regulated by a gene product. Whenever detailed information is available, the more granular children terms should be used.								biological_process											owl:Class	
GO:1902617	biolink:NamedThing	response to fluoride	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fluoride stimulus.	tmpzr1t_l9r_go_relaxed.owl								kmv	2014-01-10T19:41:49Z					biological_process											owl:Class	
GO:0010035	biolink:NamedThing	response to inorganic substance	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an inorganic substance stimulus.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0097251	biolink:NamedThing	leukotriene B4 biosynthetic process	The chemical reactions and pathways resulting in the formation of leukotriene B4, a leukotriene composed of (6Z,8E,10E,14Z)-eicosatetraenoic acid having (5S)- and (12R)-hydroxy substituents.	tmpzr1t_l9r_go_relaxed.owl	leukotriene B4 biosynthesis|leukotriene B4 formation|LTB4 synthesis|leukotriene B4 anabolism|leukotriene B4 synthesis|LTB4 anabolism|LTB4 formation|LTB4 biosynthesis							pr	2012-02-24T09:34:01Z					biological_process											owl:Class	
GO:1901617	biolink:NamedThing	organic hydroxy compound biosynthetic process	The chemical reactions and pathways resulting in the formation of organic hydroxy compound.	tmpzr1t_l9r_go_relaxed.owl	organic hydroxy compound formation|organic hydroxy compound synthesis|organic hydroxy compound anabolism|organic hydroxy compound biosynthesis							pr	2012-11-13T12:54:36Z					biological_process											owl:Class	
GO:0051045	biolink:NamedThing	negative regulation of membrane protein ectodomain proteolysis	Any process that stops, prevents, or reduces the frequency, rate or extent of membrane protein ectodomain proteolysis.	tmpzr1t_l9r_go_relaxed.owl	downregulation of membrane protein ectodomain proteolysis|down-regulation of membrane protein ectodomain proteolysis|inhibition of membrane protein ectodomain proteolysis|down regulation of membrane protein ectodomain proteolysis													biological_process											owl:Class	
GO:0051043	biolink:NamedThing	regulation of membrane protein ectodomain proteolysis	Any process that modulates the frequency, rate or extent of the proteolytic cleavage of transmembrane proteins and release of their ectodomain (extracellular domain).	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0034462	biolink:NamedThing	small-subunit processome assembly	The aggregation, arrangement and bonding together of proteins and RNA molecules to form a small-subunit processome.	tmpzr1t_l9r_go_relaxed.owl	SSU processome assembly|small subunit processome assembly													biological_process											owl:Class	
GO:0140344	biolink:NamedThing	triglyceride transfer activity	Directly binding to a triglyceride and delivering it either to an acceptor molecule or to a specific location.	tmpzr1t_l9r_go_relaxed.owl	triglyceride carrier activity							pg	2019-05-16T11:53:59Z					molecular_function											owl:Class	
GO:0120013	biolink:NamedThing	lipid transfer activity	Removes a lipid from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle. This results in intermembrane transfer of lipids.	tmpzr1t_l9r_go_relaxed.owl	lipid carrier activity|intermembrane lipid transfer activity	https://github.com/geneontology/go-ontology/issues/17648|https://github.com/geneontology/go-ontology/issues/12329						krc	2017-03-17T03:17:29Z					molecular_function											owl:Class	
GO:0050421	biolink:NamedThing	nitrite reductase (NO-forming) activity	Catalysis of the reaction: nitric oxide + H2O + ferricytochrome c = nitrite + ferrocytochrome c + 2 H+.	tmpzr1t_l9r_go_relaxed.owl	cd-cytochrome nitrite reductase activity|NO-forming nitrite reductase activity|cytochrome cd1 activity|nitrite reductase (cytochrome; NO-forming) activity|NO-forming nitrite reductase (cytochrome) activity|nitric-oxide:ferricytochrome-c oxidoreductase activity|Pseudomonas cytochrome oxidase activity|[nitrite reductase (cytochrome)]|cytochrome c-551:O(2), NO(2)(+) oxidoreductase activity|methyl viologen-nitrite reductase activity|cytochrome cd activity|cytochrome c-551:O2, NO2+ oxidoreductase activity				MetaCyc:NITRITE-REDUCTASE-CYTOCHROME-RXN|EC:1.7.2.1|RHEA:15233	Note that EC:1.7.99.3 was merged into this term.						GO:0016666		molecular_function											owl:Class	
GO:0098809	biolink:NamedThing	nitrite reductase activity	Catalysis of the reaction: nitrite + acceptor = product(s) of nitrate reduction + reduced acceptor.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0035162	biolink:NamedThing	embryonic hemopoiesis	The stages of blood cell formation that take place within the embryo.	tmpzr1t_l9r_go_relaxed.owl	embryonic haemopoiesis|embryonic hematopoiesis|embryonic haematopoiesis													biological_process											owl:Class	
GO:0030097	biolink:NamedThing	hemopoiesis	The process whose specific outcome is the progression of the myeloid and lymphoid derived organ/tissue systems of the blood and other parts of the body over time, from formation to the mature structure. The site of hemopoiesis is variable during development, but occurs primarily in bone marrow or kidney in many adult vertebrates.	tmpzr1t_l9r_go_relaxed.owl	hematopoiesis|blood cell biosynthesis|haemopoiesis|blood cell formation				Wikipedia:Haematopoiesis									biological_process											owl:Class	
GO:1902227	biolink:NamedThing	negative regulation of macrophage colony-stimulating factor signaling pathway	Any process that stops, prevents or reduces the frequency, rate or extent of macrophage colony-stimulating factor signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of M-CSF signaling pathway|down regulation of macrophage colony-stimulating factor signaling pathway|inhibition of macrophage colony-stimulating factor signalling pathway|negative regulation of M-CSF signaling pathway|downregulation of macrophage colony-stimulating factor signaling pathway|downregulation of macrophage colony-stimulating factor signalling pathway|inhibition of macrophage colony-stimulating factor signaling pathway|inhibition of M-CSF signaling pathway|downregulation of M-CSF signaling pathway|down regulation of macrophage colony-stimulating factor signalling pathway|negative regulation of macrophage colony-stimulating factor signalling pathway|down-regulation of macrophage colony-stimulating factor signaling pathway|down-regulation of macrophage colony-stimulating factor signalling pathway|down regulation of M-CSF signaling pathway							lb	2013-06-14T06:28:54Z					biological_process											owl:Class	
GO:1902226	biolink:NamedThing	regulation of macrophage colony-stimulating factor signaling pathway	Any process that modulates the frequency, rate or extent of macrophage colony-stimulating factor signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	regulation of M-CSF signaling pathway|regulation of macrophage colony-stimulating factor signalling pathway							lb	2013-06-14T06:28:42Z					biological_process											owl:Class	
GO:0001960	biolink:NamedThing	negative regulation of cytokine-mediated signaling pathway	Any process that stops, prevents, or reduces the frequency, rate or extent of the cytokine mediated signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of cytokine mediated signaling pathway|negative regulation of cytokine mediated signalling pathway|negative regulation of cytokine and chemokine mediated signaling pathway|downregulation of cytokine mediated signaling pathway|inhibition of cytokine mediated signaling pathway|down regulation of cytokine mediated signaling pathway|down-regulation of cytokine mediated signaling pathway													biological_process											owl:Class	
GO:0015021	biolink:NamedThing	heparin-sulfate lyase activity	Catalysis of the elimination of sulfate; appears to act on linkages between N-acetyl-D-glucosamine and uronate. Product is an unsaturated sugar.	tmpzr1t_l9r_go_relaxed.owl	heparitinase I|heparin-sulphate lyase activity|heparitinase II|[heparan sulfate]-sulfate lyase activity|heparitin-sulfate lyase activity|heparin-sulfate eliminase activity				MetaCyc:4.2.2.8-RXN|EC:4.2.2.8									molecular_function											owl:Class	
GO:0016837	biolink:NamedThing	carbon-oxygen lyase activity, acting on polysaccharides	Catalysis of the cleavage of a carbon-oxygen bond by the elimination of an alcohol from a polysaccharide.	tmpzr1t_l9r_go_relaxed.owl					EC:4.2.2.-									molecular_function											owl:Class	
GO:0018118	biolink:NamedThing	peptidyl-L-cysteine glutathione disulfide biosynthetic process from peptidyl-cysteine	The modification of peptidyl-cysteine by covalent addition of glutathione to form peptidyl-L-cysteine glutathione disulfide.	tmpzr1t_l9r_go_relaxed.owl	peptidyl-L-cysteine glutathione disulphide biosynthesis from peptidyl-cysteine|peptidyl-L-cysteine glutathione disulfide anabolism from peptidyl-cysteine|peptidyl-L-cysteine glutathione disulfide formation from peptidyl-cysteine|peptidyl-L-cysteine glutathione disulfide synthesis from peptidyl-cysteine|peptidyl-L-cysteine glutathione disulphide biosynthetic process from peptidyl-cysteine				RESID:AA0229									biological_process											owl:Class	
GO:0018198	biolink:NamedThing	peptidyl-cysteine modification	The modification of peptidyl-cysteine.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0031745	biolink:NamedThing	cysteinyl leukotriene receptor binding	Binding to a cysteinyl leukotriene receptor.	tmpzr1t_l9r_go_relaxed.owl	cysteinyl leukotriene receptor ligand													molecular_function											owl:Class	
GO:0001664	biolink:NamedThing	G protein-coupled receptor binding	Binding to a G protein-coupled receptor.	tmpzr1t_l9r_go_relaxed.owl	G protein coupled receptor binding|G-protein-coupled receptor ligand|G-protein coupled receptor binding|G protein coupled receptor ligand				Reactome:R-HSA-500717									molecular_function											owl:Class	
GO:0035736	biolink:NamedThing	cell proliferation involved in compound eye morphogenesis	The multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to compound eye morphogenesis.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-03-17T10:57:03Z					biological_process											owl:Class	
GO:0008283	biolink:NamedThing	cell population proliferation	The multiplication or reproduction of cells, resulting in the expansion of a cell population.	tmpzr1t_l9r_go_relaxed.owl	cell proliferation					This term was moved out from being a child of 'cellular process' because it is a cell population-level process, and cellular processes are restricted to those processes that involve individual cells. Also note that this term is intended to be used for the proliferation of cells within a multicellular organism, not for the expansion of a population of single-celled organisms.								biological_process											owl:Class	
GO:0072523	biolink:NamedThing	purine-containing compound catabolic process	The chemical reactions and pathways resulting in the breakdown of a purine-containing compound, i.e. any compound that contains purine or a formal derivative thereof.	tmpzr1t_l9r_go_relaxed.owl	purine-containing compound degradation|purine and derivative catabolic process|purine-containing compound breakdown|purine-containing compound catabolism							mah	2011-01-04T03:17:20Z					biological_process											owl:Class	
GO:0045724	biolink:NamedThing	positive regulation of cilium assembly	Any process that activates or increases the frequency, rate or extent of the formation of a cilium.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of cilium assembly|up regulation of cilium assembly|activation of cilium assembly|upregulation of cilium assembly|positive regulation of flagellum biogenesis|stimulation of cilium assembly|positive regulation of flagellum assembly													biological_process											owl:Class	
GO:0120034	biolink:NamedThing	positive regulation of plasma membrane bounded cell projection assembly	Any process that activates or increases the frequency, rate or extent of plasma membrane bounded cell projection assembly.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/13298						krc	2017-04-26T04:34:45Z					biological_process											owl:Class	
GO:0032285	biolink:NamedThing	non-myelinated axon ensheathment	The process in which a non-myelinating glial cell membrane closes around an axon.	tmpzr1t_l9r_go_relaxed.owl	ensheathment of non-myelinated axons													biological_process											owl:Class	
GO:0008366	biolink:NamedThing	axon ensheathment	Any process in which the axon of a neuron is insulated, and that insulation maintained, thereby preventing dispersion of the electrical signal.	tmpzr1t_l9r_go_relaxed.owl	cellular nerve ensheathment|nerve ensheathment|cellular axon ensheathment											GO:0042553		biological_process											owl:Class	
GO:0045740	biolink:NamedThing	positive regulation of DNA replication	Any process that activates or increases the frequency, rate or extent of DNA replication.	tmpzr1t_l9r_go_relaxed.owl	stimulation of DNA replication|activation of DNA replication|up-regulation of DNA replication|up regulation of DNA replication|upregulation of DNA replication													biological_process											owl:Class	
GO:0006275	biolink:NamedThing	regulation of DNA replication	Any process that modulates the frequency, rate or extent of DNA replication.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0070101	biolink:NamedThing	positive regulation of chemokine-mediated signaling pathway	Any process that increases the rate, frequency or extent of the series of molecular events generated as a consequence of a chemokine binding to a cell surface receptor.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of chemokine-mediated signalling pathway													biological_process											owl:Class	
GO:0001961	biolink:NamedThing	positive regulation of cytokine-mediated signaling pathway	Any process that activates or increases the frequency, rate or extent of a cytokine mediated signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of cytokine and chemokine mediated signaling pathway|positive regulation of cytokine mediated signaling pathway|positive regulation of cytokine mediated signalling pathway|upregulation of cytokine mediated signaling pathway|up regulation of cytokine mediated signaling pathway|activation of cytokine mediated signaling pathway|stimulation of cytokine mediated signaling pathway|up-regulation of cytokine mediated signaling pathway													biological_process											owl:Class	
GO:0004939	biolink:NamedThing	beta-adrenergic receptor activity	Combining with epinephrine or norepinephrine to initiate a change in cell activity via activation of a G protein, with pharmacological characteristics of beta-adrenergic receptors; the activity involves transmitting the signal to the Gs alpha subunit of a heterotrimeric G protein.	tmpzr1t_l9r_go_relaxed.owl	beta adrenoceptor													molecular_function											owl:Class	
GO:0004935	biolink:NamedThing	adrenergic receptor activity	Combining with epinephrine or norepinephrine and transmitting the signal across the membrane by activating the alpha-subunit of an associated heterotrimeric G-protein complex.	tmpzr1t_l9r_go_relaxed.owl	adrenoceptor activity				Wikipedia:Adrenergic_receptor									molecular_function											owl:Class	
GO:0042615	biolink:NamedThing	CD154 receptor binding	Binding to CD154, a receptor found on the surface of some activated lymphocytes.	tmpzr1t_l9r_go_relaxed.owl	CD40 receptor activity|CD40L binding													molecular_function											owl:Class	
GO:0005102	biolink:NamedThing	signaling receptor binding	Binding to one or more specific sites on a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.	tmpzr1t_l9r_go_relaxed.owl	receptor binding|receptor ligand|receptor-associated protein activity				Wikipedia:Ligand_(biochemistry)	Where appropriate, also consider annotating to 'receptor agonist activity ; GO:0048018'.								molecular_function											owl:Class	
GO:0050936	biolink:NamedThing	xanthophore differentiation	The process in which a relatively unspecialized cell acquires the specialized features of a xanthophore cell. Xanthophores are pigment cells derived from the neural crest. They contain pteridine and/or carotenoid pigments in structures called pterinosomes or xanthosomes. This makes them yellow to orange in appearance.	tmpzr1t_l9r_go_relaxed.owl	xanthophore cell differentiation					Note that this term refers to xanthophores in the sense of specialized pigment-producing cells, and should not be confused with the cellular component term 'xanthophore ; GO:0031633', which refers to a subcellular structure.								biological_process											owl:Class	
GO:0050931	biolink:NamedThing	pigment cell differentiation	The process in which a relatively unspecialized cell acquires the specialized features of a pigmented cell, such as a melanocyte.	tmpzr1t_l9r_go_relaxed.owl	pigmented cell differentiation|chromatophore differentiation					Note that the chromatophore mentioned here is distinct from the pigment bearing structure found in certain photosynthetic bacteria and cyanobacteria. It is also different from the plant chromoplast, which is also sometimes called a chromatophore.						GO:0043357|GO:0043358		biological_process											owl:Class	
GO:1902520	biolink:NamedThing	response to doxorubicin	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a doxorubicin stimulus.	tmpzr1t_l9r_go_relaxed.owl						Note that this term is in the subset of terms that should not be used for direct manual annotation of gene products. It was created to be used for cross-referencing by other ontologies. Direct annotations to this term may be amended during annotation QC.		dw	2013-12-02T09:44:13Z					biological_process											owl:Class	
GO:1903416	biolink:NamedThing	response to glycoside	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glycoside stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to ouabain							rl	2014-09-05T12:41:01Z					biological_process											owl:Class	
GO:1990153	biolink:NamedThing	maintenance of protein localization to heterochromatin	A process in which a protein is maintained in a location in telomeric heterochromatin.	tmpzr1t_l9r_go_relaxed.owl	maintenance of protein location in heterochromatin|maintenance of protein localisation to heterochromatin							mah	2013-07-31T15:11:37Z					biological_process											owl:Class	
GO:0032507	biolink:NamedThing	maintenance of protein location in cell	Any process in which a protein is maintained in a specific location within, or in the membrane of, a cell, and is prevented from moving elsewhere.	tmpzr1t_l9r_go_relaxed.owl	maintenance of protein localization in cell													biological_process											owl:Class	
GO:0035682	biolink:NamedThing	toll-like receptor 21 signaling pathway	Any series of molecular signals generated as a consequence of binding to toll-like receptor 21.	tmpzr1t_l9r_go_relaxed.owl	TLR21 signaling pathway|toll-like receptor 21 signalling pathway							bf	2011-02-21T02:39:39Z					biological_process											owl:Class	
GO:0020027	biolink:NamedThing	hemoglobin metabolic process	The chemical reactions and pathways involving hemoglobin, including its uptake and utilization.	tmpzr1t_l9r_go_relaxed.owl	haemoglobin metabolic process|haemoglobin metabolism|hemoglobin metabolism													biological_process											owl:Class	
GO:0044260	biolink:NamedThing	cellular macromolecule metabolic process	The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, as carried out by individual cells.	tmpzr1t_l9r_go_relaxed.owl	cellular biopolymer metabolic process|cellular macromolecule metabolism											GO:0034960		biological_process											owl:Class	
GO:0002494	biolink:NamedThing	lipid antigen transport	The directed movement of a lipid antigen into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0006869	biolink:NamedThing	lipid transport	The directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Lipids are compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0008291	biolink:NamedThing	acetylcholine metabolic process	The chemical reactions and pathways involving acetylcholine, the acetic acid ester of the organic base choline. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues.	tmpzr1t_l9r_go_relaxed.owl	acetylcholine metabolism													biological_process											owl:Class	
GO:0042133	biolink:NamedThing	neurotransmitter metabolic process	The chemical reactions and pathways involving neurotransmitters, any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell.	tmpzr1t_l9r_go_relaxed.owl	neurotransmitter metabolism													biological_process											owl:Class	
GO:0140255	biolink:NamedThing	regulation of cellular response to phosphate starvation	Any process that modulates the frequency, rate or extent of cellular response to phosphate starvation.	tmpzr1t_l9r_go_relaxed.owl								pg	2018-09-07T17:11:42Z					biological_process											owl:Class	
GO:0080135	biolink:NamedThing	regulation of cellular response to stress	Any process that modulates the frequency, rate or extent of a cellular response to stress. Cellular response to stress is a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).	tmpzr1t_l9r_go_relaxed.owl								dhl	2009-05-06T05:02:52Z					biological_process											owl:Class	
GO:0032077	biolink:NamedThing	positive regulation of deoxyribonuclease activity	Any process that activates or increases the frequency, rate or extent of deoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid.	tmpzr1t_l9r_go_relaxed.owl	DNase activator|activation of deoxyribonuclease activity|up regulation of deoxyribonuclease activity|up-regulation of deoxyribonuclease activity|deoxyribonuclease activator|stimulation of deoxyribonuclease activity|upregulation of deoxyribonuclease activity													biological_process											owl:Class	
GO:0004062	biolink:NamedThing	aryl sulfotransferase activity	Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + a phenol = adenosine 3',5'-bisphosphate + an aryl sulfate.	tmpzr1t_l9r_go_relaxed.owl	phenol sulfotransferase activity|phenol sulfokinase activity|dopamine sulfotransferase activity|p-nitrophenol sulfotransferase activity|1-naphthol phenol sulfotransferase activity|aryl sulphotransferase activity|2-naphtholsulfotransferase activity|ritodrine sulfotransferase activity|3'-phosphoadenylyl-sulfate:phenol sulfotransferase activity|4-nitrocatechol sulfokinase activity|sulfokinase activity|PST|arylsulfotransferase				MetaCyc:ARYL-SULFOTRANSFERASE-RXN|EC:2.8.2.1|Reactome:R-HSA-158849|Reactome:R-HSA-159358|Reactome:R-HSA-176474|Reactome:R-HSA-158468|Reactome:R-HSA-158860|RHEA:12164|Reactome:R-HSA-176646|Reactome:R-HSA-176585									molecular_function											owl:Class	
GO:0008146	biolink:NamedThing	sulfotransferase activity	Catalysis of the transfer of a sulfate group from 3'-phosphoadenosine 5'-phosphosulfate to the hydroxyl group of an acceptor, producing the sulfated derivative and 3'-phosphoadenosine 5'-phosphate.	tmpzr1t_l9r_go_relaxed.owl	sulphotransferase activity				Reactome:R-HSA-2022061|Reactome:R-HSA-176669|Reactome:R-HSA-176588|EC:2.8.2.-|Reactome:R-HSA-176604									molecular_function											owl:Class	
GO:0042009	biolink:NamedThing	interleukin-15 binding	Binding to interleukin-15.	tmpzr1t_l9r_go_relaxed.owl	IL-15 binding													molecular_function											owl:Class	
GO:0019955	biolink:NamedThing	cytokine binding	Binding to a cytokine, any of a group of proteins that function to control the survival, growth and differentiation of tissues and cells, and which have autocrine and paracrine activity.	tmpzr1t_l9r_go_relaxed.owl	IL binding|interleukin binding											GO:0019965		molecular_function											owl:Class	
GO:0048667	biolink:NamedThing	cell morphogenesis involved in neuron differentiation	The process in which the structures of a neuron are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a neuron.	tmpzr1t_l9r_go_relaxed.owl	neuron morphogenesis involved in differentiation													biological_process											owl:Class	
GO:0000902	biolink:NamedThing	cell morphogenesis	The developmental process in which the size or shape of a cell is generated and organized.	tmpzr1t_l9r_go_relaxed.owl	cellular morphogenesis											GO:0045791|GO:0007148|GO:0045790		biological_process											owl:Class	
GO:1900105	biolink:NamedThing	negative regulation of hyaluranon cable assembly	Any process that stops, prevents or reduces the frequency, rate or extent of hyaluranon cable assembly.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of HA cable assembly|downregulation of HA cable assembly|down regulation of hyaluranon cable assembly|inhibition of HA cable assembly|negative regulation of HA cable assembly|inhibition of hyaluranon cable assembly|down regulation of HA cable assembly|downregulation of hyaluranon cable assembly|down-regulation of hyaluranon cable assembly							yaf	2012-02-16T01:00:50Z					biological_process											owl:Class	
GO:1904251	biolink:NamedThing	regulation of bile acid metabolic process	Any process that modulates the frequency, rate or extent of bile acid metabolic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of bile acid metabolism							bf	2015-05-20T11:04:28Z					biological_process											owl:Class	
GO:0071546	biolink:NamedThing	pi-body	A P granule that contains the PIWIL2-TDRD1 module, a set of proteins that act in the primary piRNA pathway. The pi-body corresponds to the cementing material between mitochondria found in gonocytes.	tmpzr1t_l9r_go_relaxed.owl	intermitochondrial cement							mah	2010-01-12T05:44:12Z					cellular_component											owl:Class	
GO:0043186	biolink:NamedThing	P granule	A small cytoplasmic, non-membranous RNA/protein complex aggregate in the primordial germ cells of many higher eukaryotes.	tmpzr1t_l9r_go_relaxed.owl	germline granule|nuage|polar granule											GO:0018994		cellular_component											owl:Class	
GO:0002013	biolink:NamedThing	detection of carbon dioxide by vasomotor center	The process by a carbon dioxide stimulus is received and converted to a molecular signal by the vasomotor center of the central nervous system.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0003031	biolink:NamedThing	detection of carbon dioxide	The series of events in which a carbon dioxide stimulus is received by a cell and converted into a molecular signal.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1901699	biolink:NamedThing	cellular response to nitrogen compound	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrogen compound stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to nitrogen molecular entity							pr	2012-12-13T15:06:13Z					biological_process											owl:Class	
GO:0072052	biolink:NamedThing	juxtaglomerulus cell differentiation	The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the juxtaglomerulus cells of the kidney as it progresses from its formation to the mature state.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-01-25T03:58:01Z					biological_process											owl:Class	
GO:1905284	biolink:NamedThing	positive regulation of epidermal growth factor receptor signaling pathway involved in heart process	Any process that activates or increases the frequency, rate or extent of epidermal growth factor receptor signaling pathway involved in heart process.	tmpzr1t_l9r_go_relaxed.owl	activation of EGF receptor signaling pathway involved in cardiac process|activation of EGF receptor signalling pathway involved in cardiac process|up regulation of EGF receptor signalling pathway involved in cardiac process|activation of ERBB1 signaling pathway involved in heart process|upregulation of receptor tyrosine-protein kinase erbB-1 signaling pathway involved in heart process|up regulation of ERBB1 signaling pathway involved in heart process|upregulation of ERBB1 signaling pathway involved in cardiac process|positive regulation of EGFR signaling pathway involved in heart process|activation of EGF receptor signaling pathway involved in heart process|positive regulation of EGF receptor signalling pathway involved in cardiac process|upregulation of ERBB1 signaling pathway involved in heart process|upregulation of EGFR signaling pathway involved in cardiac process|up-regulation of EGFR signaling pathway involved in heart process|up-regulation of receptor tyrosine-protein kinase erbB-1 signaling pathway involved in cardiac process|positive regulation of epidermal growth factor receptor signalling pathway involved in cardiac process|up-regulation of receptor tyrosine-protein kinase erbB-1 signaling pathway involved in heart process|positive regulation of EGF receptor signaling pathway involved in heart process|positive regulation of ERBB1 signaling pathway involved in heart process|activation of epidermal growth factor receptor signaling pathway involved in cardiac process|up regulation of EGF receptor signaling pathway involved in cardiac process|up regulation of receptor tyrosine-protein kinase erbB-1 signaling pathway involved in heart process|up-regulation of epidermal growth factor receptor signaling pathway involved in cardiac process|up-regulation of EGF receptor signalling pathway involved in cardiac process|positive regulation of ERBB1 signaling pathway involved in cardiac process|positive regulation of EGF receptor signaling pathway involved in cardiac process|up regulation of epidermal growth factor receptor signalling pathway involved in heart process|up regulation of EGFR signaling pathway involved in cardiac process|positive regulation of epidermal growth factor receptor signalling pathway involved in heart process|up regulation of EGFR signaling pathway involved in heart process|up-regulation of EGF receptor signalling pathway involved in heart process|up-regulation of epidermal growth factor receptor signaling pathway involved in heart process|up regulation of epidermal growth factor receptor signaling pathway involved in cardiac process|activation of ERBB1 signaling pathway involved in cardiac process|up regulation of EGF receptor signalling pathway involved in heart process|activation of EGF receptor signalling pathway involved in heart process|positive regulation of epidermal growth factor receptor signaling pathway involved in cardiac process|activation of epidermal growth factor receptor signaling pathway involved in heart process|upregulation of EGFR signaling pathway involved in heart process|up-regulation of EGFR signaling pathway involved in cardiac process|upregulation of EGF receptor signalling pathway involved in cardiac process|upregulation of EGF receptor signaling pathway involved in heart process|up-regulation of epidermal growth factor receptor signalling pathway involved in heart process|upregulation of receptor tyrosine-protein kinase erbB-1 signaling pathway involved in cardiac process|activation of EGFR signaling pathway involved in heart process|upregulation of epidermal growth factor receptor signaling pathway involved in cardiac process|up-regulation of ERBB1 signaling pathway involved in cardiac process|upregulation of EGF receptor signaling pathway involved in cardiac process|up-regulation of ERBB1 signaling pathway involved in heart process|activation of receptor tyrosine-protein kinase erbB-1 signaling pathway involved in heart process|up-regulation of EGF receptor signaling pathway involved in heart process|positive regulation of receptor tyrosine-protein kinase erbB-1 signaling pathway involved in cardiac process|up regulation of EGF receptor signaling pathway involved in heart process|positive regulation of EGF receptor signalling pathway involved in heart process|activation of EGFR signaling pathway involved in cardiac process|positive regulation of receptor tyrosine-protein kinase erbB-1 signaling pathway involved in heart process|upregulation of epidermal growth factor receptor signalling pathway involved in heart process|activation of receptor tyrosine-protein kinase erbB-1 signaling pathway involved in cardiac process|up-regulation of EGF receptor signaling pathway involved in cardiac process|upregulation of epidermal growth factor receptor signaling pathway involved in heart process|up regulation of epidermal growth factor receptor signaling pathway involved in heart process|upregulation of epidermal growth factor receptor signalling pathway involved in cardiac process|upregulation of EGF receptor signalling pathway involved in heart process|activation of epidermal growth factor receptor signalling pathway involved in cardiac process|up regulation of ERBB1 signaling pathway involved in cardiac process|up regulation of receptor tyrosine-protein kinase erbB-1 signaling pathway involved in cardiac process|positive regulation of EGFR signaling pathway involved in cardiac process|up regulation of epidermal growth factor receptor signalling pathway involved in cardiac process|up-regulation of epidermal growth factor receptor signalling pathway involved in cardiac process|activation of epidermal growth factor receptor signalling pathway involved in heart process							bc	2016-06-20T14:40:57Z					biological_process											owl:Class	
GO:1905282	biolink:NamedThing	regulation of epidermal growth factor receptor signaling pathway involved in heart process	Any process that modulates the frequency, rate or extent of epidermal growth factor receptor signaling pathway involved in heart process.	tmpzr1t_l9r_go_relaxed.owl	regulation of EGF receptor signalling pathway involved in cardiac process|regulation of epidermal growth factor receptor signalling pathway involved in cardiac process|regulation of EGF receptor signalling pathway involved in heart process|regulation of epidermal growth factor receptor signaling pathway involved in cardiac process|regulation of EGFR signaling pathway involved in heart process|regulation of EGF receptor signaling pathway involved in heart process|regulation of ERBB1 signaling pathway involved in heart process|regulation of ERBB1 signaling pathway involved in cardiac process|regulation of epidermal growth factor receptor signalling pathway involved in heart process|regulation of receptor tyrosine-protein kinase erbB-1 signaling pathway involved in cardiac process|regulation of EGF receptor signaling pathway involved in cardiac process|regulation of EGFR signaling pathway involved in cardiac process|regulation of receptor tyrosine-protein kinase erbB-1 signaling pathway involved in heart process							bc	2016-06-20T14:40:41Z					biological_process											owl:Class	
GO:0106121	biolink:NamedThing	positive regulation of cobalamin metabolic process	Any process that activates or increases the frequency, rate or extent of a cobalamin metabolic process.	tmpzr1t_l9r_go_relaxed.owl								hjd	2018-05-01T18:07:12Z					biological_process											owl:Class	
GO:0046136	biolink:NamedThing	positive regulation of vitamin metabolic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a vitamin, one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body.	tmpzr1t_l9r_go_relaxed.owl	up regulation of vitamin metabolic process|activation of vitamin metabolic process|upregulation of vitamin metabolic process|stimulation of vitamin metabolic process|up-regulation of vitamin metabolic process|positive regulation of vitamin metabolism													biological_process											owl:Class	
GO:0031589	biolink:NamedThing	cell-substrate adhesion	The attachment of a cell to the underlying substrate via adhesion molecules.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0032745	biolink:NamedThing	positive regulation of interleukin-21 production	Any process that activates or increases the frequency, rate, or extent of interleukin-21 production.	tmpzr1t_l9r_go_relaxed.owl	stimulation of interleukin-21 production|up-regulation of interleukin-21 production|up regulation of interleukin-21 production|positive regulation of IL-21 production|activation of interleukin-21 production|upregulation of interleukin-21 production|positive regulation of interleukin-21 biosynthetic process											GO:0045392		biological_process											owl:Class	
GO:0045948	biolink:NamedThing	positive regulation of translational initiation	Any process that activates or increases the frequency, rate or extent of translational initiation.	tmpzr1t_l9r_go_relaxed.owl	stimulation of translational initiation|up-regulation of translational initiation|upregulation of translational initiation|up regulation of translational initiation|activation of translational initiation													biological_process											owl:Class	
GO:0045727	biolink:NamedThing	positive regulation of translation	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of protein synthesis|activation of protein biosynthetic process|positive regulation of protein biosynthetic process|up-regulation of protein biosynthetic process|positive regulation of protein biosynthesis|positive regulation of protein anabolism|up regulation of protein biosynthetic process|positive regulation of protein formation|upregulation of protein biosynthetic process|stimulation of protein biosynthetic process											GO:0045946		biological_process											owl:Class	
GO:0061942	biolink:NamedThing	negative regulation of c-di-GMP signaling	Any process that decreases the rate, frequency or extent of c-di-GMP signaling.	tmpzr1t_l9r_go_relaxed.owl								dph	2017-09-14T19:13:44Z					biological_process											owl:Class	
GO:0010648	biolink:NamedThing	negative regulation of cell communication	Any process that decreases the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0021753	biolink:NamedThing	superior salivary nucleus development	The process whose specific outcome is the progression of the superior salivary nucleus over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0021751	biolink:NamedThing	salivary nucleus development	The process whose specific outcome is the progression of a salivary nucleus over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0110115	biolink:NamedThing	Cdr2 medial cortical node complex	A megadalton-sized complex at the medial cortex organized as an oligomeric core of SAD family protein kinases involved in cell size-dependent localization and phosphorylation of Wee1 during interphase.	tmpzr1t_l9r_go_relaxed.owl	interphase cortical node|interphase node							kmv	2018-07-10T14:02:26Z					cellular_component											owl:Class	
GO:1902911	biolink:NamedThing	protein kinase complex	A protein complex which is capable of protein kinase activity.	tmpzr1t_l9r_go_relaxed.owl						An example of this is PKM2 in human (P14618) in PMID:24606918 (inferred from direct assay).		bhm	2014-04-17T13:52:40Z					cellular_component											owl:Class	
GO:0008120	biolink:NamedThing	ceramide glucosyltransferase activity	Catalysis of the reaction: UDP-glucose + N-acylsphingosine = UDP + D-glucosyl-N-acylsphingosine.	tmpzr1t_l9r_go_relaxed.owl	ceramide:UDP-glucose glucosyltransferase activity|UDP-glucose:ceramide glucosyltransferase activity|UDP-glucose:N-acylsphingosine D-glucosyltransferase activity|ceramide:UDPGlc glucosyltransferase activity|glucosylceramide synthase activity|UDP-glucose-ceramide glucosyltransferase activity|UDPglucose:N-acylsphingosine D-glucosyltransferase activity|uridine diphosphoglucose-ceramide glucosyltransferase activity				EC:2.4.1.80|MetaCyc:CERAMIDE-GLUCOSYLTRANSFERASE-RXN|RHEA:12088|Reactome:R-HSA-1638104									molecular_function											owl:Class	
GO:0035251	biolink:NamedThing	UDP-glucosyltransferase activity	Catalysis of the transfer of a glucosyl group from UDP-glucose to an acceptor molecule.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-1912353|MetaCyc:PHENOL-BETA-GLUCOSYLTRANSFERASE-RXN									molecular_function											owl:Class	
GO:1902955	biolink:NamedThing	positive regulation of early endosome to recycling endosome transport	Any process that activates or increases the frequency, rate or extent of early endosome to recycling endosome transport.	tmpzr1t_l9r_go_relaxed.owl	up regulation of early endosome to recycling endosome transport|upregulation of early endosome to recycling endosome transport|activation of early endosome to recycling endosome transport|up-regulation of early endosome to recycling endosome transport							sjp	2014-05-02T09:06:29Z					biological_process											owl:Class	
GO:0033288	biolink:NamedThing	ATPase-coupled hydroxyectoine transmembrane transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + hydroxyectoine(out/in) = ADP + phosphate + hydroxyectoine(in/out).	tmpzr1t_l9r_go_relaxed.owl	ATP-dependent hydroxyectoine transmembrane transporter activity|hydroxyectoine transmembrane transporter activity|hydroxyectoine-transporting ATPase activity											GO:0033287		molecular_function											owl:Class	
GO:0015651	biolink:NamedThing	quaternary ammonium group transmembrane transporter activity	Enables the transfer of quaternary ammonium groups from one side of a membrane to the other. Quaternary ammonium groups are any compound that can be regarded as derived from ammonium hydroxide or an ammonium salt by replacement of all four hydrogen atoms of the NH4+ ion by organic groups.	tmpzr1t_l9r_go_relaxed.owl	quaternary amine transmembrane transporter activity|quaternary ammonium compound transporter activity											GO:0015202		molecular_function											owl:Class	
GO:0099140	biolink:NamedThing	presynaptic actin cytoskeleton organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins in the presynaptic actin cytoskeleton.	tmpzr1t_l9r_go_relaxed.owl								dos	2017-06-09T18:34:19Z					biological_process											owl:Class	
GO:0030036	biolink:NamedThing	actin cytoskeleton organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins.	tmpzr1t_l9r_go_relaxed.owl	actin cytoskeleton organization and biogenesis|actin modulating activity|actin cytoskeleton organisation													biological_process											owl:Class	
GO:0033398	biolink:NamedThing	zeatin biosynthetic process	The chemical reactions and pathways resulting in the formation of zeatin, 2-methyl-4-(9H-purin-6-ylamino)but-2-en-1-ol.	tmpzr1t_l9r_go_relaxed.owl	zeatin biosynthesis|zeatin anabolism|zeatin formation|zeatin synthesis													biological_process											owl:Class	
GO:0072522	biolink:NamedThing	purine-containing compound biosynthetic process	The chemical reactions and pathways resulting in the formation of a purine-containing compound, i.e. any compound that contains purine or a formal derivative thereof.	tmpzr1t_l9r_go_relaxed.owl	purine-containing compound formation|purine-containing compound synthesis|purine-containing compound anabolism|purine and derivative biosynthetic process|purine-containing compound biosynthesis							mah	2011-01-04T03:15:29Z					biological_process											owl:Class	
GO:0102516	biolink:NamedThing	delphinidin 3-O-glucoside 7-O-glucosyltransferase (feruloyl-glucose dependent) activity	Catalysis of the reaction: delphinidin 3-O-beta-D-glucoside + 1-O-feruloyl-beta-D-glucose <=> delphinidin 3,7-di O-beta-D-glucoside + ferulate + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-14448									molecular_function											owl:Class	
GO:0016758	biolink:NamedThing	hexosyltransferase activity	Catalysis of the transfer of a hexosyl group from one compound (donor) to another (acceptor).	tmpzr1t_l9r_go_relaxed.owl	transferase activity, transferring hexosyl groups				EC:2.4.1.-									molecular_function											owl:Class	
GO:0034734	biolink:NamedThing	transcription factor TFIIIC1 complex	A transcription factor complex that forms part of the TFIIIC complex, observed in human. The complex is poorly characterized, but contains the 250-kDa form of HsBdp1, and is thought to include nuclear factor 1 (NF1). It stimulates binding by human TFIIIC2 and is required for transcription activity.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0090576	biolink:NamedThing	RNA polymerase III transcription regulator complex	A transcription factor complex that acts at a regulatory region of a gene transcribed by RNA polymerase III.	tmpzr1t_l9r_go_relaxed.owl	RNA polymerase III transcription factor complex							tb	2014-05-09T14:04:37Z					cellular_component											owl:Class	
GO:0000960	biolink:NamedThing	regulation of mitochondrial RNA catabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving catabolism in the mitochondrion of RNA transcribed from the mitochondrial genome.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1901627	biolink:NamedThing	negative regulation of postsynaptic membrane organization	Any process that stops, prevents or reduces the frequency, rate or extent of postsynaptic membrane organization.	tmpzr1t_l9r_go_relaxed.owl	inhibition of postsynaptic membrane organisation|down regulation of postsynaptic membrane organisation|negative regulation of postsynaptic membrane organisation|down-regulation of postsynaptic membrane organization|downregulation of postsynaptic membrane organisation|negative regulation of post-synaptic membrane organization|inhibition of postsynaptic membrane organization|down-regulation of postsynaptic membrane organisation|down regulation of postsynaptic membrane organization|downregulation of postsynaptic membrane organization							ans	2012-11-15T11:40:20Z					biological_process											owl:Class	
GO:1900142	biolink:NamedThing	negative regulation of oligodendrocyte apoptotic process	Any process that stops, prevents or reduces the frequency, rate or extent of oligodendrocyte apoptotic process.	tmpzr1t_l9r_go_relaxed.owl	downregulation of oligodendrocyte apoptosis|downregulation of oligodendrocyte apoptotic process|negative regulation of oligodendrocyte apoptosis|down regulation of oligodendrocyte apoptosis|down-regulation of oligodendrocyte apoptosis|down regulation of oligodendrocyte apoptotic process|inhibition of oligodendrocyte apoptosis|down-regulation of oligodendrocyte apoptotic process|inhibition of oligodendrocyte apoptotic process							yaf	2012-03-06T10:22:50Z					biological_process											owl:Class	
GO:0034351	biolink:NamedThing	negative regulation of glial cell apoptotic process	Any process that stops, prevents, or reduces the frequency, rate, or extent of glial cell apoptotic process.	tmpzr1t_l9r_go_relaxed.owl	downregulation of glial cell apoptosis|inhibition of glial cell apoptosis|negative regulation of glial cell apoptosis|down-regulation of glial cell apoptosis|down regulation of glial cell apoptosis													biological_process											owl:Class	
GO:0061010	biolink:NamedThing	gall bladder development	The progression of the gall bladder over time, from its initial formation to the mature structure. The gall bladder is a cavitated organ that stores bile.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-01-22T09:38:44Z					biological_process											owl:Class	
GO:0072112	biolink:NamedThing	glomerular visceral epithelial cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a glomerular visceral epithelial cell. A glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells.	tmpzr1t_l9r_go_relaxed.owl	podocyte differentiation							mah	2010-02-22T10:52:11Z					biological_process											owl:Class	
GO:0072311	biolink:NamedThing	glomerular epithelial cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a glomerular epithelial cell. Glomerular epithelial cells are specialized epithelial cells that form part of the glomerulus; there are two types, glomerular parietal epithelial cells and glomerular visceral epithelial cells.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-04-09T06:49:21Z					biological_process											owl:Class	
GO:0046477	biolink:NamedThing	glycosylceramide catabolic process	The chemical reactions and pathways resulting in the breakdown of glycosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of a monosaccharide (or derivative) by a ceramide group.	tmpzr1t_l9r_go_relaxed.owl	glycosylceramide degradation|glycosylceramide breakdown|glycosylceramide catabolism													biological_process											owl:Class	
GO:0006677	biolink:NamedThing	glycosylceramide metabolic process	The chemical reactions and pathways involving glycosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of a monosaccharide (or derivative) by a ceramide group.	tmpzr1t_l9r_go_relaxed.owl	glycosylceramide metabolism													biological_process											owl:Class	
GO:1904344	biolink:NamedThing	regulation of gastric mucosal blood circulation	Any process that modulates the frequency, rate or extent of gastric mucosal blood circulation.	tmpzr1t_l9r_go_relaxed.owl	regulation of stomach mucosal blood circulation							sl	2015-06-11T21:20:31Z					biological_process											owl:Class	
GO:0033283	biolink:NamedThing	ATPase-coupled organic acid transmembrane transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + organic acid(out/in) = ADP + phosphate + organic acid(in/out).	tmpzr1t_l9r_go_relaxed.owl	organic acid-transporting ATPase activity|ATP-dependent organic acid transmembrane transporter activity													molecular_function											owl:Class	
GO:2000168	biolink:NamedThing	negative regulation of planar cell polarity pathway involved in neural tube closure	Any process that stops, prevents, or reduces the frequency, rate or extent of planar cell polarity pathway involved in neural tube closure.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-10-05T01:08:56Z					biological_process											owl:Class	
GO:1904179	biolink:NamedThing	positive regulation of adipose tissue development	Any process that activates or increases the frequency, rate or extent of adipose tissue development.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of adipogenesis|activation of adipogenesis|up regulation of adipogenesis|upregulation of adipose tissue development|up-regulation of adipogenesis|up-regulation of adipose tissue development|upregulation of adipogenesis|up regulation of adipose tissue development|activation of adipose tissue development							sl	2015-04-29T20:01:13Z					biological_process											owl:Class	
GO:1904177	biolink:NamedThing	regulation of adipose tissue development	Any process that modulates the frequency, rate or extent of adipose tissue development.	tmpzr1t_l9r_go_relaxed.owl	regulation of adipogenesis							sl	2015-04-29T20:01:01Z					biological_process											owl:Class	
GO:0018071	biolink:NamedThing	NAD(P)-cysteine ADP-ribosyltransferase activity	Catalysis of the reaction: NAD(P)+ + L-cysteine = nicotinamide + N2-(ADP-D-ribosyl)-L-cysteine.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0080134	biolink:NamedThing	regulation of response to stress	Any process that modulates the frequency, rate or extent of a response to stress. Response to stress is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).	tmpzr1t_l9r_go_relaxed.owl						Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.		dhl	2009-05-06T04:51:28Z					biological_process											owl:Class	
GO:0007500	biolink:NamedThing	mesodermal cell fate determination	The cell fate determination process in which a cell becomes capable of differentiating autonomously into a mesoderm cell regardless of its environment; upon determination, the cell fate cannot be reversed.	tmpzr1t_l9r_go_relaxed.owl	mesoderm cell fate determination					Note that this term was 'mesoderm determination'. Changed string to make more consistent with parent term 'cell fate determination'.								biological_process											owl:Class	
GO:0001709	biolink:NamedThing	cell fate determination	A process involved in cell fate commitment. Once determination has taken place, a cell becomes committed to differentiate down a particular pathway regardless of its environment.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Cell_fate_determination									biological_process											owl:Class	
GO:0042538	biolink:NamedThing	hyperosmotic salinity response	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, an increase in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.	tmpzr1t_l9r_go_relaxed.owl	response to hyperosmotic salt stress|salt tolerance													biological_process											owl:Class	
GO:0009651	biolink:NamedThing	response to salt stress	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.	tmpzr1t_l9r_go_relaxed.owl	response to ionic osmotic stress|salinity response													biological_process											owl:Class	
GO:0002371	biolink:NamedThing	dendritic cell cytokine production	Any process that contributes to cytokine production by a dendritic cell.	tmpzr1t_l9r_go_relaxed.owl						Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.								biological_process											owl:Class	
GO:0002367	biolink:NamedThing	cytokine production involved in immune response	The appearance of a cytokine due to biosynthesis or secretion following a cellular stimulus contributing to an immune response, resulting in an increase in its intracellular or extracellular levels.	tmpzr1t_l9r_go_relaxed.owl	cytokine production during immune response|cytokine biosynthetic process involved in immune response|cytokine secretion during immune response|cytokine secretion involved in immune response					Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.						GO:0002374|GO:0002375		biological_process											owl:Class	
GO:1901547	biolink:NamedThing	negative regulation of synaptic vesicle lumen acidification	Any process that stops, prevents or reduces the frequency, rate or extent of synaptic vesicle lumen acidification.	tmpzr1t_l9r_go_relaxed.owl	downregulation of synaptic vesicle lumen acidification|inhibition of synaptic vesicle lumen acidification|inhibition of synaptic vesicle lumen pH reduction|negative regulation of proton loading|negative regulation of synaptic vesicle lumen pH reduction|down regulation of synaptic vesicle lumen acidification|downregulation of synaptic vesicle lumen pH reduction|down-regulation of synaptic vesicle lumen pH reduction|down regulation of synaptic vesicle lumen pH reduction|down-regulation of synaptic vesicle lumen acidification							dsf	2012-10-26T16:09:28Z					biological_process											owl:Class	
GO:1904063	biolink:NamedThing	negative regulation of cation transmembrane transport	Any process that stops, prevents or reduces the frequency, rate or extent of cation transmembrane transport.	tmpzr1t_l9r_go_relaxed.owl	downregulation of cation transmembrane transport|inhibition of cation transmembrane transport|down-regulation of cation transmembrane transport|down regulation of cation transmembrane transport							sl	2015-03-18T21:11:50Z					biological_process											owl:Class	
GO:0009443	biolink:NamedThing	pyridoxal 5'-phosphate salvage	Any process that generates pyridoxal 5'-phosphate, the active form of vitamin B6, from derivatives of it without de novo synthesis.	tmpzr1t_l9r_go_relaxed.owl	pyridoxal 5' phosphate salvage				MetaCyc:PLPSAL-PWY									biological_process											owl:Class	
GO:0043094	biolink:NamedThing	cellular metabolic compound salvage	Any process which produces a useful metabolic compound from derivatives of it without de novo synthesis, as carried out by individual cells.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0062044	biolink:NamedThing	negative regulation of cardiac epithelial to mesenchymal transition	Any process that stops or decreases the rate, frequency or extent of cardiac epithelial to mesenchymal transition, a transition where a cardiac epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell.	tmpzr1t_l9r_go_relaxed.owl								dph	2018-05-10T18:21:00Z					biological_process											owl:Class	
GO:0010719	biolink:NamedThing	negative regulation of epithelial to mesenchymal transition	Any process that decreases the rate, frequency, or extent of epithelial to mesenchymal transition. Epithelial to mesenchymal transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0010782	biolink:NamedThing	proboscis morphogenesis, labial disc-derived	The process in which the anatomical structures of the proboscis that are derived from the labial disc are generated and organized.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0009886	biolink:NamedThing	post-embryonic animal morphogenesis	The process, occurring after animal embryonic development, by which anatomical structures are generated and organized.	tmpzr1t_l9r_go_relaxed.owl	post-embryonic morphogenesis of an anatomical structure													biological_process											owl:Class	
GO:0008340	biolink:NamedThing	determination of adult lifespan	The control of viability and duration in the adult phase of the life-cycle.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0052162	biolink:NamedThing	modulation by symbiont of defense-related host calcium ion flux	Any process in which an organism modulates the frequency, rate or extent of calcium ion fluxes as part of the defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	modulation by organism of defense-related calcium ion flux in other organism involved in symbiotic interaction|modulation by organism of defense-related host Ca2+ flux											GO:0052301		biological_process											owl:Class	
GO:0052031	biolink:NamedThing	modulation by symbiont of host defense response	Any process in which an organism modulates the frequency, rate or extent of the defense response of its host, the response mounted by the host in response to the presence of the organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	modulation by organism of defense response of other organism involved in symbiotic interaction|pathogenesis|mitigation by symbiont of host defense response											GO:0052255		biological_process											owl:Class	
GO:2000279	biolink:NamedThing	negative regulation of DNA biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of DNA biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of DNA synthesis|negative regulation of DNA anabolism|negative regulation of DNA formation|negative regulation of DNA biosynthesis							yaf	2010-12-08T04:48:20Z					biological_process											owl:Class	
GO:2000278	biolink:NamedThing	regulation of DNA biosynthetic process	Any process that modulates the frequency, rate or extent of DNA biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of DNA formation|regulation of DNA synthesis|regulation of DNA biosynthesis|regulation of DNA anabolism							yaf	2010-12-08T04:48:15Z					biological_process											owl:Class	
GO:0002644	biolink:NamedThing	negative regulation of tolerance induction	Any process that stops, prevents, or reduces the frequency, rate, or extent of tolerance induction.	tmpzr1t_l9r_go_relaxed.owl	inhibition of tolerance induction|down-regulation of tolerance induction|downregulation of tolerance induction|down regulation of tolerance induction													biological_process											owl:Class	
GO:0051093	biolink:NamedThing	negative regulation of developmental process	Any process that stops, prevents or reduces the rate or extent of development, the biological process whose specific outcome is the progression of an organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).	tmpzr1t_l9r_go_relaxed.owl	downregulation of developmental process|inhibition of developmental process|down-regulation of developmental process|down regulation of developmental process													biological_process											owl:Class	
GO:0004962	biolink:NamedThing	endothelin receptor activity	Combining with endothelin and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.	tmpzr1t_l9r_go_relaxed.owl	endothelin-B receptor activity|endothelin-A receptor activity											GO:0001599|GO:0001600		molecular_function											owl:Class	
GO:0008528	biolink:NamedThing	G protein-coupled peptide receptor activity	Combining with a peptide and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.	tmpzr1t_l9r_go_relaxed.owl	peptide receptor activity, G protein coupled|G protein coupled peptide receptor activity|peptide receptor activity, G-protein coupled|G-protein coupled peptide receptor activity													molecular_function											owl:Class	
GO:1903543	biolink:NamedThing	positive regulation of exosomal secretion	Any process that activates or increases the frequency, rate or extent of exosomal secretion.	tmpzr1t_l9r_go_relaxed.owl	activation of exosomal secretion|up regulation of exosomal secretion|activation of exosomal secretory pathway|up regulation of secretion of exosome|upregulation of exosomal secretory pathway|activation of secretion of exosome|up regulation of extracellular vesicular exosome secretion|upregulation of extracellular vesicular exosome secretion|up-regulation of exosomal secretory pathway|positive regulation of exosomal protein secretion|activation of extracellular vesicular exosome secretion|positive regulation of extracellular vesicular exosome secretion|up regulation of exosomal protein secretion|upregulation of exosomal secretion|upregulation of exosomal protein secretion|activation of exosomal protein secretion|upregulation of secretion of exosome|positive regulation of secretion of exosome|up-regulation of exosomal secretion|up regulation of exosomal secretory pathway|up-regulation of secretion of exosome|up-regulation of exosomal protein secretion|up-regulation of extracellular vesicular exosome secretion|positive regulation of exosomal secretory pathway							pga	2014-10-14T11:39:10Z					biological_process											owl:Class	
GO:1903541	biolink:NamedThing	regulation of exosomal secretion	Any process that modulates the frequency, rate or extent of exosomal secretion.	tmpzr1t_l9r_go_relaxed.owl	regulation of exosomal protein secretion|regulation of extracellular vesicular exosome secretion|regulation of exosomal secretory pathway|regulation of secretion of exosome							pga	2014-10-14T11:38:52Z					biological_process											owl:Class	
GO:1903365	biolink:NamedThing	regulation of fear response	Any process that modulates the frequency, rate or extent of fear response.	tmpzr1t_l9r_go_relaxed.owl	regulation of physiological fear response							mr	2014-08-21T23:21:36Z					biological_process											owl:Class	
GO:0007058	biolink:NamedThing	spindle assembly involved in female meiosis II	The aggregation, arrangement and bonding together of a set of components to form the spindle during meiosis II of a meiotic cell cycle in females. An example of this is found in Drosophila melanogaster.	tmpzr1t_l9r_go_relaxed.owl	female meiosis II spindle assembly													biological_process											owl:Class	
GO:0051225	biolink:NamedThing	spindle assembly	The aggregation, arrangement and bonding together of a set of components to form the spindle, the array of microtubules and associated molecules that serves to move duplicated chromosomes apart.	tmpzr1t_l9r_go_relaxed.owl	bipolar spindle biosynthesis|spindle formation|bipolar spindle formation|spindle biosynthesis											GO:0051226|GO:0051227		biological_process											owl:Class	
GO:0099553	biolink:NamedThing	trans-synaptic signaling by endocannabinoid, modulating synaptic transmission	Cell-cell signaling between presynapse and postsynapse, via the release and reception of endocannabinoid ligands, that modulates the synaptic transmission properties of the synapse.	tmpzr1t_l9r_go_relaxed.owl						Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.								biological_process											owl:Class	
GO:0099552	biolink:NamedThing	trans-synaptic signaling by lipid, modulating synaptic transmission	Cell-cell signaling between presynapse and postsynapse, via the release and reception of lipid molecules, that modulates the synaptic transmission properties of the synapse.	tmpzr1t_l9r_go_relaxed.owl						Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.								biological_process											owl:Class	
GO:0150011	biolink:NamedThing	regulation of neuron projection arborization	Any process that modulates the frequency, rate or extent of the process in which the anatomical structures of a neuron projection are generated and organized into branches.	tmpzr1t_l9r_go_relaxed.owl	regulation of neurite arborization|regulation of neuron projection branching|regulation of neurite branching							bc	2017-12-13T16:32:34Z					biological_process											owl:Class	
GO:0031344	biolink:NamedThing	regulation of cell projection organization	Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell projections.	tmpzr1t_l9r_go_relaxed.owl	regulation of cell projection organisation|regulation of cell projection organization and biogenesis													biological_process											owl:Class	
GO:0002273	biolink:NamedThing	plasmacytoid dendritic cell differentiation	The process in which a relatively unspecialized hemopoietic precursor cell acquires the specialized features of a plasmacytoid dendritic cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0002270	biolink:NamedThing	plasmacytoid dendritic cell activation	A change in the morphology or behavior of a plasmacytoid dendritic cell resulting from exposure to an activating factor such as a cellular or soluble ligand.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0046450	biolink:NamedThing	dethiobiotin metabolic process	The chemical reactions and pathways involving dethiobiotin, a derivative of biotin formed by replacing the sulfur atom by two hydrogen atoms.	tmpzr1t_l9r_go_relaxed.owl	desthiobiotin metabolic process|desthiobiotin metabolism|dethiobiotin metabolism													biological_process											owl:Class	
GO:1901360	biolink:NamedThing	organic cyclic compound metabolic process	The chemical reactions and pathways involving organic cyclic compound.	tmpzr1t_l9r_go_relaxed.owl	organic cyclic compound metabolism							bf	2012-09-14T09:03:51Z					biological_process											owl:Class	
GO:1900980	biolink:NamedThing	regulation of phenazine biosynthetic process	Any process that modulates the frequency, rate or extent of phenazine biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of dibenzopyrazine biosynthesis|regulation of dibenzo-p-diazine biosynthesis|regulation of dibenzopyrazine biosynthetic process|regulation of azophenylene biosynthesis|regulation of azophenylene biosynthetic process|regulation of acridizine biosynthesis|regulation of acridizine biosynthetic process|regulation of dibenzo-p-diazine biosynthetic process							tt	2012-06-14T04:04:39Z					biological_process											owl:Class	
GO:1905215	biolink:NamedThing	negative regulation of RNA binding	Any process that stops, prevents or reduces the frequency, rate or extent of RNA binding.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of RNA binding|inhibition of RNA binding|down regulation of RNA binding|downregulation of RNA binding							bf	2016-06-06T10:21:04Z					biological_process											owl:Class	
GO:0033989	biolink:NamedThing	3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity	Catalysis of the reaction: (24R,25R)-3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA = (24E)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA + H2O.	tmpzr1t_l9r_go_relaxed.owl	(24R,25R)-3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA hydro-lyase [(24E)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA-forming] activity|46 kDa hydratase 2 activity|(24R,25R)-3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA hydro-lyase activity|D-3-hydroxyacyl-CoA dehydratase activity				EC:4.2.1.107|Reactome:R-HSA-193535|Reactome:R-HSA-192331|MetaCyc:4.2.1.107-RXN|RHEA:18933									molecular_function											owl:Class	
GO:0016836	biolink:NamedThing	hydro-lyase activity	Catalysis of the cleavage of a carbon-oxygen bond by elimination of water.	tmpzr1t_l9r_go_relaxed.owl					EC:4.2.1.-|Reactome:R-HSA-9014627									molecular_function											owl:Class	
GO:1900095	biolink:NamedThing	regulation of dosage compensation by inactivation of X chromosome	Any process that modulates the frequency, rate or extent of dosage compensation, by inactivation of X chromosome.	tmpzr1t_l9r_go_relaxed.owl	regulation of Barr body formation|regulation of X chromosome inactivation|regulation of chromosome inactivation							hjd	2012-02-14T07:29:45Z					biological_process											owl:Class	
GO:0010468	biolink:NamedThing	regulation of gene expression	Any process that modulates the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.	tmpzr1t_l9r_go_relaxed.owl	regulation of gene product expression|gene regulation|regulation of protein expression				Wikipedia:Regulation_of_gene_expression	This class covers any process that regulates the rate of production of a mature gene product, and so includes processes that regulate that rate by regulating the level, stability or availability of intermediates in the process of gene expression.  For example, it covers any process that regulates the level, stability or availability of mRNA or circRNA for translation and thereby regulates the rate of production of the encoded protein via translation.								biological_process											owl:Class	
GO:1905002	biolink:NamedThing	positive regulation of membrane repolarization during atrial cardiac muscle cell action potential	Any process that activates or increases the frequency, rate or extent of membrane repolarization during atrial cardiac muscle cell action potential.	tmpzr1t_l9r_go_relaxed.owl	up regulation of electrocardiogram QRS complex|upregulation of electrocardiogram QRS complex|upregulation of membrane repolarization during atrial cardiac muscle cell action potential|positive regulation of atrial repolarization|activation of membrane repolarization during atrial cardiac muscle cell action potential|up-regulation of electrocardiogram QRS complex|upregulation of atrial repolarization|up regulation of membrane repolarization during atrial cardiac muscle cell action potential|activation of atrial repolarization|up-regulation of atrial repolarization|activation of electrocardiogram QRS complex|up regulation of atrial repolarization|up-regulation of membrane repolarization during atrial cardiac muscle cell action potential|positive regulation of electrocardiogram QRS complex							rph	2016-03-01T13:28:21Z					biological_process											owl:Class	
GO:0016926	biolink:NamedThing	protein desumoylation	The process in which a SUMO protein (small ubiquitin-related modifier) is cleaved from its target protein.	tmpzr1t_l9r_go_relaxed.owl	protein desumolation|desumoylation											GO:0016928		biological_process											owl:Class	
GO:0018205	biolink:NamedThing	peptidyl-lysine modification	The modification of peptidyl-lysine.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1900161	biolink:NamedThing	regulation of phospholipid scramblase activity	Any process that modulates the frequency, rate or extent of phospholipid scramblase activity.	tmpzr1t_l9r_go_relaxed.owl								rph	2012-03-08T10:57:19Z					biological_process											owl:Class	
GO:0061091	biolink:NamedThing	regulation of phospholipid translocation	Any process that modulates the frequency, rate or extent of the translocation, or flipping, of phospholipid molecules from one monolayer of a membrane bilayer to the opposite monolayer.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-04-26T01:54:22Z					biological_process											owl:Class	
GO:0150063	biolink:NamedThing	visual system development	The process whose specific outcome is the progression of the visual system over time, from its formation to the mature structure, including the eye, parts of the central nervous system (CNS) involved in processing of visual inputs, and connecting nerve pathways.	tmpzr1t_l9r_go_relaxed.owl	visual pathway development|optic pathway development							bc	2018-07-23T10:31:58Z					biological_process											owl:Class	
GO:0048880	biolink:NamedThing	sensory system development	The process whose specific outcome is the progression of a sensory system over time from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0099183	biolink:NamedThing	trans-synaptic signaling by BDNF, modulating synaptic transmission	Cell-cell signaling between presynapse and postsynapse, via the vesicular release and reception of brain derived neurotrophic factor (BDNF), that modulates the synaptic transmission properties of the synapse.	tmpzr1t_l9r_go_relaxed.owl						Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.		dos	2017-12-01T18:25:24Z					biological_process											owl:Class	
GO:0099550	biolink:NamedThing	trans-synaptic signaling, modulating synaptic transmission	Cell-cell signaling between presynapse and postsynapse, across the synaptic cleft, that modulates the synaptic transmission properties of the synapse.	tmpzr1t_l9r_go_relaxed.owl						Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.								biological_process											owl:Class	
GO:1900141	biolink:NamedThing	regulation of oligodendrocyte apoptotic process	Any process that modulates the frequency, rate or extent of oligodendrocyte apoptotic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of oligodendrocyte apoptosis							yaf	2012-03-06T10:22:45Z					biological_process											owl:Class	
GO:0034350	biolink:NamedThing	regulation of glial cell apoptotic process	Any process that modulates the frequency, rate, or extent of glial cell apoptotic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of glial cell apoptosis													biological_process											owl:Class	
GO:0042867	biolink:NamedThing	pyruvate catabolic process	The chemical reactions and pathways resulting in the breakdown of pyruvate, 2-oxopropanoate.	tmpzr1t_l9r_go_relaxed.owl	pyruvate catabolism|pyruvate degradation|pyruvate breakdown													biological_process											owl:Class	
GO:0072329	biolink:NamedThing	monocarboxylic acid catabolic process	The chemical reactions and pathways resulting in the breakdown of monocarboxylic acids, any organic acid containing one carboxyl (-COOH) group.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-11-02T04:41:55Z					biological_process											owl:Class	
GO:0002094	biolink:NamedThing	polyprenyltransferase activity	Catalysis of the transfer of multiple prenyl groups from one compound (donor) to another (acceptor).	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0004659	biolink:NamedThing	prenyltransferase activity	Catalysis of the transfer of a prenyl group from one compound (donor) to another (acceptor).	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-6806674|MetaCyc:GPPSYN-RXN									molecular_function											owl:Class	
GO:1900999	biolink:NamedThing	nitrobenzene biosynthetic process	The chemical reactions and pathways resulting in the formation of nitrobenzene.	tmpzr1t_l9r_go_relaxed.owl	nitrobenzene formation|nitrobenzene biosynthesis|nitrobenzene synthesis|nitrobenzene anabolism							yaf	2012-06-14T02:54:32Z					biological_process											owl:Class	
GO:0019438	biolink:NamedThing	aromatic compound biosynthetic process	The chemical reactions and pathways resulting in the formation of aromatic compounds, any substance containing an aromatic carbon ring.	tmpzr1t_l9r_go_relaxed.owl	aromatic compound biosynthesis|aromatic compound formation|aromatic compound anabolism|aromatic hydrocarbon biosynthesis|aromatic hydrocarbon biosynthetic process|aromatic compound synthesis													biological_process											owl:Class	
GO:0051674	biolink:NamedThing	localization of cell	Any process in which a cell is transported to, and/or maintained in, a specific location.	tmpzr1t_l9r_go_relaxed.owl	establishment and maintenance of cell localization|cell localization|establishment and maintenance of localization of cell|localisation of cell													biological_process											owl:Class	
GO:0009987	biolink:NamedThing	cellular process	Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.	tmpzr1t_l9r_go_relaxed.owl	single-organism cellular process|cell growth and/or maintenance|cellular physiological process|cell physiology							jl	2012-12-11T16:56:55Z			GO:0044763|GO:0050875|GO:0008151		biological_process											owl:Class	
GO:0042923	biolink:NamedThing	neuropeptide binding	Interacting selectively and non-covalently and stoichiometrically with neuropeptides, peptides with direct synaptic effects (peptide neurotransmitters) or indirect modulatory effects on the nervous system (peptide neuromodulators).	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0042277	biolink:NamedThing	peptide binding	Binding to a peptide, an organic compound comprising two or more amino acids linked by peptide bonds.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0099066	biolink:NamedThing	integral component of neuronal dense core vesicle membrane	The component of the neuronal dense core vesicle membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0031301	biolink:NamedThing	integral component of organelle membrane	The component of the organelle membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.	tmpzr1t_l9r_go_relaxed.owl	integral to organelle membrane													cellular_component											owl:Class	
GO:0034835	biolink:NamedThing	2-mercaptobenzothiazole monooxygenase activity	Catalysis of the reaction: 2-mercaptobenzothiazole + 1/2 O2 = 6-hydroxy-2-mercaptobenzothiazole.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r1178|EC:1.13.12.-									molecular_function											owl:Class	
GO:0016703	biolink:NamedThing	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases)	Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from one donor, and one oxygen atom is incorporated into a donor.	tmpzr1t_l9r_go_relaxed.owl					EC:1.13.12.-									molecular_function											owl:Class	
GO:1903201	biolink:NamedThing	regulation of oxidative stress-induced cell death	Any process that modulates the frequency, rate or extent of oxidative stress-induced cell death.	tmpzr1t_l9r_go_relaxed.owl	regulation of cell death in response to oxidative stress							bf	2014-07-21T16:10:30Z					biological_process											owl:Class	
GO:1901094	biolink:NamedThing	negative regulation of protein homotetramerization	Any process that stops, prevents or reduces the frequency, rate or extent of protein homotetramerization.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of protein homotetramer assembly|inhibition of protein homotetramer assembly|down-regulation of protein homotetramer biosynthetic process|down regulation of protein homotetramer formation|down regulation of protein homotetramer assembly|inhibition of protein homotetramer formation|down-regulation of protein homotetramerization|negative regulation of protein homotetramer formation|downregulation of protein homotetramer formation|downregulation of protein homotetramer assembly|inhibition of protein homotetramer biosynthetic process|inhibition of protein homotetramerization|negative regulation of protein homotetramer biosynthetic process|down-regulation of protein homotetramer formation|down-regulation of protein homotetramer biosynthesis|down regulation of protein homotetramerization|inhibition of protein homotetramer biosynthesis|downregulation of protein homotetramer biosynthesis|negative regulation of protein homotetramer biosynthesis|down regulation of protein homotetramer biosynthesis|downregulation of protein homotetramer biosynthetic process|negative regulation of protein homotetramer assembly|downregulation of protein homotetramerization|down regulation of protein homotetramer biosynthetic process							pm	2012-07-06T12:57:58Z					biological_process											owl:Class	
GO:0032463	biolink:NamedThing	negative regulation of protein homooligomerization	Any process that stops, prevents, or reduces the frequency, rate or extent of protein homooligomerization.	tmpzr1t_l9r_go_relaxed.owl	downregulation of protein homooligomerization|inhibition of protein homooligomerization|down-regulation of protein homooligomerization|down regulation of protein homooligomerization													biological_process											owl:Class	
GO:0048754	biolink:NamedThing	branching morphogenesis of an epithelial tube	The process in which the anatomical structures of branches in an epithelial tube are generated and organized. A tube is a long hollow cylinder.	tmpzr1t_l9r_go_relaxed.owl	tubulogenesis													biological_process											owl:Class	
GO:0061138	biolink:NamedThing	morphogenesis of a branching epithelium	The process in which the anatomical structures of a branched epithelium are generated and organized.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-05-25T09:05:34Z					biological_process											owl:Class	
GO:0034246	biolink:NamedThing	mitochondrial transcription factor activity	Interacting with the mitochondrial promoter DNA to modulate transcription by the mitochondrial RNA polymerase.	tmpzr1t_l9r_go_relaxed.owl	mitochondrial RNA polymerase binding promoter specificity activity|mitochondrial RNA polymerase promoter specificity activity|mitochondrial transcription initiation factor activity|mitochondrial RNA polymerase transcription factor activity, sequence-specific DNA binding|transcription factor activity, mitochondrial RNA polymerase core promoter sequence-specific DNA binding|mitochondrial sequence-specific DNA binding transcription factor activity|transcription factor activity, mitochondrial proximal promoter sequence-specific binding|mitochondrial polymerase transcription factor activity|mitochondrial sequence-specific DNA-binding transcription factor activity|mitochondrial DNA-binding transcription factor activity|transcription factor activity, mitochondrial RNA polymerase core promoter proximal region sequence-specific binding|mitochondrial RNA polymerase core promoter proximal region sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding mitochondrial RNA polymerase transcription factor activity|mitochondrial RNA polymerase core promoter sequence-specific DNA binding transcription factor activity	https://github.com/geneontology/go-ontology/issues/14908|https://github.com/geneontology/go-ontology/issues/19891						krc	2011-01-27T01:55:21Z			GO:0000998|GO:0001142|GO:0001144|GO:0001143		molecular_function											owl:Class	
GO:0003700	biolink:NamedThing	DNA-binding transcription factor activity	A transcription regulator activity that modulates transcription of gene sets via selective and non-covalent binding to a specific double-stranded genomic DNA sequence (sometimes referred to as a motif) within a cis-regulatory region. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.	tmpzr1t_l9r_go_relaxed.owl	sequence-specific DNA binding bacterial-type RNA polymerase transcription factor activity|metal ion regulated sequence-specific DNA binding transcription factor activity|transcription factor activity, bacterial-type RNA polymerase core promoter proximal region sequence-specific binding|bacterial-type RNA polymerase transcription factor activity, sequence-specific DNA binding|transcription factor activity, metal ion regulated sequence-specific DNA binding|bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding|transcription factor activity, bacterial-type RNA polymerase proximal promoter sequence-specific DNA binding|sequence-specific DNA binding transcription factor activity|bacterial-type RNA polymerase transcription enhancer sequence-specific DNA binding transcription factor activity|bacterial-type RNA polymerase core promoter proximal region sequence-specific DNA binding transcription factor activity|metal ion regulated sequence-specific DNA binding bacterial-type RNA polymerase transcription factor activity|nucleic acid binding transcription factor activity|DNA binding transcription factor activity|gene-specific transcription factor activity|transcription factor activity|bacterial-type DNA binding transcription factor activity|transcription factor activity, bacterial-type RNA polymerase transcription enhancer sequence-specific binding	https://github.com/geneontology/go-ontology/issues/16534|https://github.com/geneontology/go-ontology/issues/15704|https://github.com/geneontology/go-ontology/issues/20253				Usage guidance: Most DNA-binding transcription factors do not have enzymatic activity. The presence of specific DNA-binding domains known to be present in DNA-binding transcription factors (HOX, GATA etc) should be used to help decide whether a protein is a DNA binding transcription factor or a coregulator. If a protein has an enzymatic activity (for example, ubiquitin ligase, histone acetyl transferase) and no known DNA binding domain, consider annotating to GO:0003712 transcription coregulator activity. Special care should be taken with proteins containing zinc fingers, Myb/SANT and ARID domains, since only a subset of proteins containing these domains directly and selectively bind to regulatory DNA motifs in cis-regulatory regions.		krc	2010-10-21T04:37:54Z			GO:0001204|GO:0001151|GO:0001199|GO:0001131|GO:0000130|GO:0001130|GO:0001071		molecular_function											owl:Class	
GO:0060349	biolink:NamedThing	bone morphogenesis	The process in which bones are generated and organized.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0009887	biolink:NamedThing	animal organ morphogenesis	Morphogenesis of an animal organ. An organ is defined as a tissue or set of tissues that work together to perform a specific function or functions. Morphogenesis is the process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.	tmpzr1t_l9r_go_relaxed.owl	histogenesis and organogenesis													biological_process											owl:Class	
GO:0009167	biolink:NamedThing	purine ribonucleoside monophosphate metabolic process	The chemical reactions and pathways involving purine ribonucleoside monophosphate, a compound consisting of a purine base linked to a ribose sugar esterified with phosphate on the sugar.	tmpzr1t_l9r_go_relaxed.owl	purine ribonucleoside monophosphate metabolism													biological_process											owl:Class	
GO:0009161	biolink:NamedThing	ribonucleoside monophosphate metabolic process	The chemical reactions and pathways involving a ribonucleoside monophosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with phosphate on the sugar.	tmpzr1t_l9r_go_relaxed.owl	ribonucleoside monophosphate metabolism													biological_process											owl:Class	
GO:0035075	biolink:NamedThing	response to ecdysone	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ecdysone stimulus.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0036314	biolink:NamedThing	response to sterol	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sterol stimulus.	tmpzr1t_l9r_go_relaxed.owl								bf	2012-08-21T14:50:14Z					biological_process											owl:Class	
GO:0002935	biolink:NamedThing	tRNA (adenine-C2-)-methyltransferase activity	Catalysis of the reaction: 2 S-adenosyl-L-methionine + adenine(37) in tRNA = S-adenosyl-L-homocysteine + 5'-deoxyadenosine + L-methionine + C2-methyladenine(37) in a tRNA.	tmpzr1t_l9r_go_relaxed.owl								hjd	2012-09-04T14:39:56Z					molecular_function											owl:Class	
GO:0008169	biolink:NamedThing	C-methyltransferase activity	Catalysis of the transfer of a methyl group to the carbon atom of an acceptor molecule.	tmpzr1t_l9r_go_relaxed.owl					EC:2.1.1.-									molecular_function											owl:Class	
GO:0047961	biolink:NamedThing	glycine N-acyltransferase activity	Catalysis of the reaction: acyl-CoA + glycine = CoA + N-acylglycine.	tmpzr1t_l9r_go_relaxed.owl	glycine acyltransferase activity|acyl-CoA:glycine N-acyltransferase activity|glycine-N-acylase activity				Reactome:R-HSA-2534040|RHEA:19869|MetaCyc:GLYCINE-N-ACYLTRANSFERASE-RXN|EC:2.3.1.13									molecular_function											owl:Class	
GO:0016410	biolink:NamedThing	N-acyltransferase activity	Catalysis of the transfer of an acyl group to a nitrogen atom on the acceptor molecule.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-177160									molecular_function											owl:Class	
GO:0061419	biolink:NamedThing	positive regulation of transcription from RNA polymerase II promoter in response to hypoxia	Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a hypoxia stimulus.	tmpzr1t_l9r_go_relaxed.owl								dph	2012-01-23T01:07:43Z					biological_process											owl:Class	
GO:0061418	biolink:NamedThing	regulation of transcription from RNA polymerase II promoter in response to hypoxia	Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a hypoxia stimulus.	tmpzr1t_l9r_go_relaxed.owl								dph	2012-01-23T01:05:59Z					biological_process											owl:Class	
GO:1900724	biolink:NamedThing	positive regulation of protein adenylylation	Any process that activates or increases the frequency, rate or extent of protein adenylylation.	tmpzr1t_l9r_go_relaxed.owl	upregulation of protein adenylylation|up regulation of protein amino acid adenylylation|up-regulation of protein amino acid adenylylation|up-regulation of protein adenylation|up regulation of protein AMPylation|up-regulation of protein adenylylation|positive regulation of protein AMPylation|positive regulation of protein amino acid adenylylation|up regulation of protein adenylation|upregulation of protein AMPylation|up-regulation of protein AMPylation|activation of protein adenylylation|activation of protein AMPylation|upregulation of protein amino acid adenylylation|activation of protein amino acid adenylylation|up regulation of protein adenylylation|activation of protein adenylation|upregulation of protein adenylation|positive regulation of protein adenylation							jl	2012-05-24T03:16:13Z					biological_process											owl:Class	
GO:1905865	biolink:NamedThing	negative regulation of Atg1/ULK1 kinase complex assembly	Any process that stops, prevents or reduces the frequency, rate or extent of Atg1/ULK1 kinase complex assembly.	tmpzr1t_l9r_go_relaxed.owl	downregulation of ATG1/ULK1 kinase complex formation|down-regulation of ULK1 signaling complex formation|down-regulation of ATG1/ULK1 kinase complex formation|inhibition of ATG1/ULK1 kinase complex formation|down-regulation of ATG1-ATG13 complex formation|down regulation of Atg1p signalling complex formation|down regulation of Atg1p signalling complex assembly|negative regulation of ULK1-ATG13-FIP200 complex assembly|inhibition of ATG1/ULK1 signaling complex formation|down-regulation of Atg1p signalling complex formation|down-regulation of ATG1/ULK1 signaling complex assembly|down regulation of ULK1 signaling complex assembly|down-regulation of ATG1/ULK1 kinase complex assembly|downregulation of Atg1p signalling complex assembly|negative regulation of Atg1p signalling complex assembly|negative regulation of ULK1 signaling complex formation|down-regulation of ULK1-ATG13-RB1CC1 complex formation|down regulation of ATG1/ULK1 signaling complex formation|inhibition of ATG1-ATG13 complex assembly|negative regulation of Atg1p signalling complex formation|down-regulation of ATG1 kinase complex assembly|negative regulation of ATG1-ATG13 complex formation|inhibition of ULK1 signaling complex assembly|downregulation of ATG1-ATG13 complex assembly|inhibition of ULK1-ATG13-FIP200 complex formation|down regulation of ATG1/ULK1 signaling complex assembly|inhibition of ATG1 kinase complex formation|down-regulation of Atg1p signalling complex assembly|down regulation of ATG1 kinase complex assembly|down regulation of ULK1-ATG13-RB1CC1 complex assembly|down regulation of ATG1-ATG13 complex assembly|down regulation of ULK1-ATG13-FIP200 complex formation|downregulation of ULK1-ATG13-RB1CC1 complex assembly|negative regulation of ATG1/ULK1 signaling complex formation|negative regulation of ATG1/ULK1 signaling complex assembly|down-regulation of ATG1/ULK1 signaling complex formation|down-regulation of ULK1 signaling complex assembly|down-regulation of ULK1-ATG13-RB1CC1 complex assembly|negative regulation of ULK1-ATG13-RB1CC1 complex formation|downregulation of ULK1-ATG13-FIP200 complex formation|inhibition of ATG1 kinase complex assembly|down regulation of ULK1 signaling complex formation|inhibition of ATG1/ULK1 kinase complex assembly|negative regulation of ULK1-ATG13-RB1CC1 complex assembly|down-regulation of ULK1-ATG13-FIP200 complex assembly|negative regulation of ATG1 kinase complex assembly|downregulation of ATG1 kinase complex formation|negative regulation of ATG1 kinase complex formation|downregulation of ATG1/ULK1 signaling complex assembly|negative regulation of ULK1 signaling complex assembly|downregulation of ULK1 signaling complex assembly|downregulation of ATG1 kinase complex assembly|downregulation of ATG1-ATG13 complex formation|negative regulation of ATG1-ATG13 complex assembly|inhibition of ATG1/ULK1 signaling complex assembly|downregulation of ULK1-ATG13-FIP200 complex assembly|negative regulation of ATG1/ULK1 kinase complex formation|inhibition of ATG1-ATG13 complex formation|downregulation of ATG1/ULK1 signaling complex formation|inhibition of ULK1-ATG13-RB1CC1 complex formation|downregulation of ULK1-ATG13-RB1CC1 complex formation|down regulation of ULK1-ATG13-RB1CC1 complex formation|down regulation of ATG1/ULK1 kinase complex assembly|down regulation of ATG1 kinase complex formation|inhibition of ULK1-ATG13-FIP200 complex assembly|inhibition of ULK1 signaling complex formation|down regulation of ULK1-ATG13-FIP200 complex assembly|downregulation of Atg1p signalling complex formation|downregulation of ULK1 signaling complex formation|down-regulation of ATG1-ATG13 complex assembly|down-regulation of ATG1 kinase complex formation|down regulation of ATG1-ATG13 complex formation|inhibition of Atg1p signalling complex assembly|down regulation of ATG1/ULK1 kinase complex formation|inhibition of ULK1-ATG13-RB1CC1 complex assembly|inhibition of Atg1p signalling complex formation|down-regulation of ULK1-ATG13-FIP200 complex formation|downregulation of ATG1/ULK1 kinase complex assembly|negative regulation of ULK1-ATG13-FIP200 complex formation							pr	2017-01-26T13:23:35Z					biological_process											owl:Class	
GO:0043791	biolink:NamedThing	dimethylamine methyltransferase activity	Catalysis of the reaction: dimethylamine + a dimethylamine corrinoid protein = a methylated dimethylamine corrinoid protein + methylamine.	tmpzr1t_l9r_go_relaxed.owl	dimethylamine-specific methylcobalamin:coenzyme M methyltransferase activity|DMAMT 1|dimethylamine:corrinoid methyltransferase activity|mtbB1|DMA methyltransferase 1|MT1				MetaCyc:RXN-8100|EC:2.1.1.249|RHEA:41175	This function is the first step in the pathway of methanogenesis from dimethylamine.								molecular_function											owl:Class	
GO:0008168	biolink:NamedThing	methyltransferase activity	Catalysis of the transfer of a methyl group to an acceptor molecule.	tmpzr1t_l9r_go_relaxed.owl	methylase				Reactome:R-HSA-212269|Reactome:R-HSA-71286|EC:2.1.1.-|Reactome:R-HSA-6800149|Reactome:R-HSA-379464|Reactome:R-HSA-379387							GO:0004480		molecular_function											owl:Class	
GO:0061281	biolink:NamedThing	specification of mesonephric connecting tubule identity	The process in which the connecting tubule of the mesonephric nephron acquires its identity.	tmpzr1t_l9r_go_relaxed.owl	specification of mesonephric collecting tubule identity							dph	2010-09-02T01:26:09Z					biological_process											owl:Class	
GO:0061282	biolink:NamedThing	specification of mesonephric nephron tubule identity	The process in which the tubules arranged along the proximal/distal axis of the mesonephric nephron acquire their identity.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-09-02T01:37:44Z					biological_process											owl:Class	
GO:0033944	biolink:NamedThing	beta-galactofuranosidase activity	Catalysis of the hydrolysis of terminal non-reducing beta-D-galactofuranosides, releasing galactose.	tmpzr1t_l9r_go_relaxed.owl	exo-beta-galactofuranosidase activity|beta-D-galactofuranosidase activity|exo-beta-D-galactofuranosidase activity|beta-D-galactofuranoside hydrolase activity				MetaCyc:3.2.1.146-RXN|EC:3.2.1.146									molecular_function											owl:Class	
GO:0004553	biolink:NamedThing	hydrolase activity, hydrolyzing O-glycosyl compounds	Catalysis of the hydrolysis of any O-glycosyl bond.	tmpzr1t_l9r_go_relaxed.owl	O-glucosyl hydrolase activity				Reactome:R-HSA-6786652|Reactome:R-HSA-9661820|Reactome:R-HSA-5694563|EC:3.2.1.-							GO:0016800		molecular_function											owl:Class	
GO:0039517	biolink:NamedThing	modulation by virus of host protein serine/threonine phosphatase activity	The process in which a virus effects a change in host protein serine/threonine phosphatase activity.	tmpzr1t_l9r_go_relaxed.owl	regulation by virus of host protein serine/threonine phosphatase activity|modulation by virus of protein serine/threonine phosphatase activity in host							bf	2011-06-16T03:04:14Z					biological_process											owl:Class	
GO:0019054	biolink:NamedThing	modulation by virus of host cellular process	The process in which a virus effects a change in the processes and activities of its host organism.	tmpzr1t_l9r_go_relaxed.owl	regulation by virus of host cellular process|modulation of cellular process in host by virus|modification by virus of host cellular process|regulation of host cellular process by virus|regulation of cellular process in host by virus|modulation by virus of host process|viral host cell process manipulation													biological_process											owl:Class	
GO:2000901	biolink:NamedThing	cyclodextrin catabolic process	The chemical reactions and pathways resulting in the breakdown of a cyclodextrin.	tmpzr1t_l9r_go_relaxed.owl	cyclodextrin catabolism							jl	2011-07-28T03:19:13Z					biological_process											owl:Class	
GO:0009313	biolink:NamedThing	oligosaccharide catabolic process	The chemical reactions and pathways resulting in the breakdown of oligosaccharides, molecules with between two and (about) 20 monosaccharide residues connected by glycosidic linkages.	tmpzr1t_l9r_go_relaxed.owl	oligosaccharide breakdown|multicellular organismal oligosaccharide catabolic process|oligosaccharide degradation|oligosaccharide catabolism											GO:0051689		biological_process											owl:Class	
GO:0014007	biolink:NamedThing	negative regulation of microglia differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of microglia differentiation, the process in which a relatively unspecialized cell acquires specialized features of a microglial cell.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of microglial cell differentiation|inhibition of microglia differentiation|downregulation of microglia differentiation|down-regulation of microglia differentiation|down regulation of microglia differentiation													biological_process											owl:Class	
GO:0051033	biolink:NamedThing	RNA transmembrane transporter activity	Enables the transfer of RNA, ribonucleic acid, from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-203906									molecular_function											owl:Class	
GO:0051032	biolink:NamedThing	nucleic acid transmembrane transporter activity	Enables the transfer of nucleic acids from one side of a membrane to the other. Nucleic acids are single or double-stranded polynucleotides involved in the storage, transmission and transfer of genetic information.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0098940	biolink:NamedThing	anterograde trans-synaptic signaling by nitric oxide	Cell-cell signaling from presynapse to postynapse, across the synaptic cleft, mediated by nitric oxide.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0099548	biolink:NamedThing	trans-synaptic signaling by nitric oxide	Cell-cell signaling between presynapse and postsynapse mediated by nitric oxide.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0019418	biolink:NamedThing	sulfide oxidation	The chemical reactions and pathways resulting in the conversion of sulfide to elemental sulfur in a higher oxidation state, or to sulfite or sulfate.	tmpzr1t_l9r_go_relaxed.owl	sulphide oxidation				MetaCyc:P222-PWY									biological_process											owl:Class	
GO:0006790	biolink:NamedThing	sulfur compound metabolic process	The chemical reactions and pathways involving the nonmetallic element sulfur or compounds that contain sulfur, such as the amino acids methionine and cysteine or the tripeptide glutathione.	tmpzr1t_l9r_go_relaxed.owl	sulphur metabolism|sulphur metabolic process|sulfur metabolism				Wikipedia:Sulfur_metabolism									biological_process											owl:Class	
GO:0000979	biolink:NamedThing	RNA polymerase II core promoter sequence-specific DNA binding	Binding to a DNA sequence that is part of the core promoter of a RNA polymerase II-transcribed gene.	tmpzr1t_l9r_go_relaxed.owl								krc	2010-08-10T02:17:28Z					molecular_function											owl:Class	
GO:0000977	biolink:NamedThing	RNA polymerase II transcription regulatory region sequence-specific DNA binding	Binding to a specific sequence of DNA that is part of a regulatory region that controls the transcription of a gene or cistron by RNA polymerase II.	tmpzr1t_l9r_go_relaxed.owl	RNA polymerase II regulatory region DNA binding	https://github.com/geneontology/go-ontology/issues/19312				To minimize ambiguity in the use of the word "promoter" in GO, we have chosen the phrase "transcription regulatory region" to refer to all of the regulatory regions. Regulatory regions in the DNA which control initiation may include the "core promoter" where the basal transcription machinery binds, the "core promoter proximal region" where regulatory factors other than the basal machinery bind. There are also additional regulatory regions, in both the DNA and the RNA transcript, which regulate elongation or termination of transcription.		krc	2010-08-10T11:05:36Z			GO:0001012		molecular_function											owl:Class	
GO:0060785	biolink:NamedThing	regulation of apoptosis involved in tissue homeostasis	Any process that modulates the occurrence or rate of cell death by apoptosis that results in the maintenance of the steady-state number of cells within a tissue.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-07-31T01:49:54Z					biological_process											owl:Class	
GO:0060223	biolink:NamedThing	retinal rod cell fate commitment	The process in which the developmental fate of a cell becomes restricted such that it will develop into a retinal rod cell. A retinal rod cell is one of the two photoreceptor subtypes in a camera-type eye.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0060220	biolink:NamedThing	camera-type eye photoreceptor cell fate commitment	The process in which the developmental fate of a cell becomes restricted such that it will develop into a photoreceptor cell in a camera-type eye.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0015754	biolink:NamedThing	allose transmembrane transport	The process in which allose is transported across a lipid bilayer, from one side of a membrane to the other. Allose is an aldohexose similar to glucose, differing only in the configuration of the hydroxyl group of C-3.	tmpzr1t_l9r_go_relaxed.owl	allose transport													biological_process											owl:Class	
GO:0008645	biolink:NamedThing	hexose transmembrane transport	The process in which hexose is transported across a membrane. Hexoses are aldoses with a chain of six carbon atoms in the molecule.	tmpzr1t_l9r_go_relaxed.owl	hexose transport|hexose membrane transport|high-affinity hexose transport|low-affinity hexose transport					Note that this term is not intended for use in annotating lateral movement within membranes.		bf	2010-04-08T10:27:23Z			GO:0008647|GO:0008646|GO:0035428		biological_process											owl:Class	
GO:2000829	biolink:NamedThing	negative regulation of parathyroid hormone secretion	Any process that stops, prevents or reduces the frequency, rate or extent of parathyroid hormone secretion.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of parathormone secretion|negative regulation of PTH secretion|negative regulation of parathyrin secretion							bf	2011-07-26T08:37:57Z					biological_process											owl:Class	
GO:0051241	biolink:NamedThing	negative regulation of multicellular organismal process	Any process that stops, prevents, or reduces the frequency, rate or extent of an organismal process, the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs.	tmpzr1t_l9r_go_relaxed.owl	downregulation of multicellular organismal process|down regulation of multicellular organismal process|inhibition of multicellular organismal process|down-regulation of multicellular organismal process													biological_process											owl:Class	
GO:1905559	biolink:NamedThing	positive regulation of mitotic nuclear envelope disassembly	Any process that activates or increases the frequency, rate or extent of mitotic nuclear envelope disassembly.	tmpzr1t_l9r_go_relaxed.owl	up regulation of mitotic nuclear envelope disassembly|up-regulation of mitotic nuclear envelope breakdown|up-regulation of mitotic nuclear envelope degradation|up regulation of mitotic nuclear envelope degradation|upregulation of mitotic nuclear envelope breakdown|positive regulation of mitotic nuclear envelope catabolism|up-regulation of mitotic nuclear envelope catabolism|upregulation of mitotic nuclear envelope catabolism|upregulation of mitotic nuclear envelope disassembly|activation of mitotic nuclear envelope degradation|activation of mitotic nuclear envelope breakdown|positive regulation of mitotic nuclear envelope breakdown|upregulation of mitotic nuclear envelope degradation|positive regulation of mitotic nuclear envelope degradation|up regulation of mitotic nuclear envelope breakdown|activation of mitotic nuclear envelope catabolism|up-regulation of mitotic nuclear envelope disassembly|activation of mitotic nuclear envelope disassembly|up regulation of mitotic nuclear envelope catabolism							hbye	2016-10-14T13:15:17Z					biological_process											owl:Class	
GO:1905557	biolink:NamedThing	regulation of mitotic nuclear envelope disassembly	Any process that modulates the frequency, rate or extent of mitotic nuclear envelope disassembly.	tmpzr1t_l9r_go_relaxed.owl	regulation of mitotic nuclear envelope breakdown|regulation of mitotic nuclear envelope catabolism|regulation of mitotic nuclear envelope degradation							hbye	2016-10-14T13:14:57Z					biological_process											owl:Class	
GO:1902963	biolink:NamedThing	negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of metalloendopeptidase activity involved in amyloid precursor protein catabolic process.	tmpzr1t_l9r_go_relaxed.owl	down regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolism|negative regulation of metalloendoprotease activity involved in amyloid precursor protein breakdown|down-regulation of metalloendoproteinase activity involved in amyloid precursor protein degradation|downregulation of metalloendoproteinase activity involved in amyloid precursor protein breakdown|inhibition of metalloendoproteinase activity involved in amyloid precursor protein catabolism|down-regulation of metalloendoprotease activity involved in amyloid precursor protein catabolic process|inhibition of metalloendoproteinase activity involved in APP catabolic process|negative regulation of metalloendoprotease activity involved in amyloid precursor protein degradation|downregulation of metalloendoproteinase activity involved in amyloid precursor protein catabolic process|down regulation of metalloendoprotease activity involved in amyloid precursor protein degradation|negative regulation of metalloendoproteinase activity involved in amyloid precursor protein degradation|downregulation of metalloendoprotease activity involved in amyloid precursor protein catabolic process|down-regulation of metalloendoproteinase activity involved in APP catabolic process|downregulation of metalloendoproteinase activity involved in amyloid precursor protein degradation|inhibition of metalloendoproteinase activity involved in amyloid precursor protein breakdown|inhibition of metalloendopeptidase activity involved in amyloid precursor protein catabolism|down-regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process|inhibition of metalloendopeptidase activity involved in amyloid precursor protein catabolic process|down-regulation of metalloendoproteinase activity involved in amyloid precursor protein breakdown|negative regulation of metalloendopeptidase activity involved in APP catabolism|down-regulation of metalloendopeptidase activity involved in APP catabolism|down regulation of metalloendoproteinase activity involved in amyloid precursor protein breakdown|inhibition of metalloendoprotease activity involved in APP catabolic process|negative regulation of metalloendoproteinase activity involved in APP catabolic process|negative regulation of metalloendopeptidase activity involved in amyloid precursor protein degradation|down regulation of metalloendoprotease activity involved in amyloid precursor protein catabolism|inhibition of metalloendoprotease activity involved in amyloid precursor protein catabolic process|inhibition of metalloendoprotease activity involved in amyloid precursor protein degradation|negative regulation of metalloendoproteinase activity involved in amyloid precursor protein breakdown|down regulation of metalloendoprotease activity involved in APP catabolism|down regulation of metalloendoproteinase activity involved in APP catabolism|down regulation of metalloendoproteinase activity involved in APP catabolic process|down-regulation of metalloendopeptidase activity involved in APP catabolic process|inhibition of metalloendoprotease activity involved in amyloid precursor protein breakdown|down-regulation of metalloendopeptidase activity involved in amyloid precursor protein breakdown|down regulation of metalloendopeptidase activity involved in amyloid precursor protein breakdown|downregulation of metalloendoprotease activity involved in APP catabolism|inhibition of metalloendoprotease activity involved in APP catabolism|downregulation of metalloendopeptidase activity involved in APP catabolism|negative regulation of metalloendoprotease activity involved in APP catabolism|downregulation of metalloendopeptidase activity involved in amyloid precursor protein degradation|negative regulation of metalloendoproteinase activity involved in APP catabolism|downregulation of metalloendoprotease activity involved in APP catabolic process|negative regulation of metalloendoprotease activity involved in APP catabolic process|down-regulation of metalloendoproteinase activity involved in amyloid precursor protein catabolism|negative regulation of metalloendoproteinase activity involved in amyloid precursor protein catabolism|negative regulation of metalloendoprotease activity involved in amyloid precursor protein catabolism|inhibition of metalloendopeptidase activity involved in amyloid precursor protein breakdown|negative regulation of metalloendoprotease activity involved in amyloid precursor protein catabolic process|inhibition of metalloendoprotease activity involved in amyloid precursor protein catabolism|down-regulation of metalloendoproteinase activity involved in APP catabolism|inhibition of metalloendoproteinase activity involved in APP catabolism|negative regulation of metalloendopeptidase activity involved in amyloid precursor protein breakdown|down-regulation of metalloendoprotease activity involved in APP catabolism|inhibition of metalloendopeptidase activity involved in amyloid precursor protein degradation|downregulation of metalloendopeptidase activity involved in APP catabolic process|downregulation of metalloendoproteinase activity involved in APP catabolism|down-regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolism|down regulation of metalloendoprotease activity involved in amyloid precursor protein catabolic process|down regulation of metalloendoproteinase activity involved in amyloid precursor protein catabolic process|inhibition of metalloendopeptidase activity involved in APP catabolism|downregulation of metalloendoproteinase activity involved in APP catabolic process|inhibition of metalloendoproteinase activity involved in amyloid precursor protein catabolic process|downregulation of metalloendopeptidase activity involved in amyloid precursor protein breakdown|down-regulation of metalloendoproteinase activity involved in amyloid precursor protein catabolic process|down regulation of metalloendopeptidase activity involved in APP catabolism|negative regulation of metalloendopeptidase activity involved in APP catabolic process|down regulation of metalloendoproteinase activity involved in amyloid precursor protein degradation|negative regulation of metalloendoproteinase activity involved in amyloid precursor protein catabolic process|down regulation of metalloendoprotease activity involved in amyloid precursor protein breakdown|inhibition of metalloendopeptidase activity involved in APP catabolic process|down-regulation of metalloendopeptidase activity involved in amyloid precursor protein degradation|down-regulation of metalloendoprotease activity involved in amyloid precursor protein catabolism|down-regulation of metalloendoprotease activity involved in APP catabolic process|downregulation of metalloendoprotease activity involved in amyloid precursor protein breakdown|down regulation of metalloendopeptidase activity involved in APP catabolic process|downregulation of metalloendoprotease activity involved in amyloid precursor protein degradation|negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolism|down-regulation of metalloendoprotease activity involved in amyloid precursor protein breakdown|downregulation of metalloendoproteinase activity involved in amyloid precursor protein catabolism|downregulation of metalloendopeptidase activity involved in amyloid precursor protein catabolism|down regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process|inhibition of metalloendoproteinase activity involved in amyloid precursor protein degradation|down regulation of metalloendoproteinase activity involved in amyloid precursor protein catabolism|down regulation of metalloendoprotease activity involved in APP catabolic process|downregulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process|downregulation of metalloendoprotease activity involved in amyloid precursor protein catabolism|down regulation of metalloendopeptidase activity involved in amyloid precursor protein degradation|down-regulation of metalloendoprotease activity involved in amyloid precursor protein degradation							sjp	2014-05-06T09:12:01Z					biological_process											owl:Class	
GO:1902992	biolink:NamedThing	negative regulation of amyloid precursor protein catabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of amyloid precursor protein catabolic process.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of APP catabolism|inhibition of amyloid precursor protein breakdown|down regulation of APP catabolic process|negative regulation of amyloid precursor protein breakdown|inhibition of amyloid precursor protein catabolism|down regulation of amyloid precursor protein catabolic process|down regulation of APP catabolism|inhibition of amyloid precursor protein degradation|down-regulation of amyloid precursor protein degradation|down regulation of amyloid precursor protein catabolism|negative regulation of APP catabolic process|down-regulation of amyloid precursor protein catabolism|down-regulation of amyloid precursor protein catabolic process|downregulation of amyloid precursor protein catabolic process|down-regulation of APP catabolic process|downregulation of APP catabolism|inhibition of APP catabolic process|downregulation of amyloid precursor protein degradation|down regulation of amyloid precursor protein degradation|downregulation of amyloid precursor protein catabolism|downregulation of APP catabolic process|down-regulation of amyloid precursor protein breakdown|downregulation of amyloid precursor protein breakdown|down-regulation of APP catabolism|inhibition of APP catabolism|negative regulation of amyloid precursor protein degradation|inhibition of amyloid precursor protein catabolic process|down regulation of amyloid precursor protein breakdown|negative regulation of amyloid precursor protein catabolism							rl	2014-05-08T14:21:10Z					biological_process											owl:Class	
GO:0009425	biolink:NamedThing	bacterial-type flagellum basal body	One of the three major substructures of the bacterial-type flagellum, the basal body is embedded in the cell envelope (the plasma membrane, peptidoglycan cell wall, and, if one is present, the outer membrane); it houses the secretion apparatus that exports the more distal components and the flagellar motor.	tmpzr1t_l9r_go_relaxed.owl	flagellin-based flagellum basal body|flagellar basal body													cellular_component											owl:Class	
GO:0086051	biolink:NamedThing	membrane repolarization during Purkinje myocyte action potential	The process in which ions are transported across a membrane such that the Purkinje myocyte membrane potential changes in the direction from the positive membrane potential at the peak of the action potential towards the negative resting potential.	tmpzr1t_l9r_go_relaxed.owl								dph	2011-11-16T11:51:56Z					biological_process											owl:Class	
GO:0086013	biolink:NamedThing	membrane repolarization during cardiac muscle cell action potential	The process in which ions are transported across a membrane such that the cardiac muscle cell plasma membrane potential changes in the direction from the positive membrane potential at the peak of the action potential towards the negative resting potential.	tmpzr1t_l9r_go_relaxed.owl								tb	2011-11-10T08:23:25Z					biological_process											owl:Class	
GO:0030870	biolink:NamedThing	Mre11 complex	Trimeric protein complex that possesses endonuclease activity; involved in meiotic recombination, DNA repair and checkpoint signaling. In Saccharomyces cerevisiae, the complex comprises Mre11p, Rad50p, and Xrs2p; complexes identified in other species generally contain proteins orthologous to the Saccharomyces cerevisiae proteins.	tmpzr1t_l9r_go_relaxed.owl	RAD50-MRE11-NBN complex|RMX complex|Rad50 complex|MRN complex|Rad50-Rad32-Nbs1 complex|MRX complex													cellular_component											owl:Class	
GO:1901392	biolink:NamedThing	regulation of transforming growth factor beta1 activation	Any process that modulates the frequency, rate or extent of transforming growth factor beta1 activation.	tmpzr1t_l9r_go_relaxed.owl	regulation of TGFB1 activation|regulation of transforming growth factor-beta1 activation|regulation of L-TGF-beta 1 activation|regulation of latent-TGF-beta1 activation|regulation of TGFbeta 1 activation|regulation of TGF-beta 1 activation							bf	2012-10-01T10:40:06Z					biological_process											owl:Class	
GO:0006245	biolink:NamedThing	TDP catabolic process	The chemical reactions and pathways resulting in the breakdown of TDP, ribosylthymine diphosphate.	tmpzr1t_l9r_go_relaxed.owl	TDP breakdown|TDP catabolism|TDP degradation													biological_process											owl:Class	
GO:0046043	biolink:NamedThing	TDP metabolic process	The chemical reactions and pathways involving TDP, ribosylthymine diphosphate.	tmpzr1t_l9r_go_relaxed.owl	TDP metabolism													biological_process											owl:Class	
GO:0018283	biolink:NamedThing	iron incorporation into metallo-sulfur cluster	The incorporation of iron into a metallo-sulfur cluster.	tmpzr1t_l9r_go_relaxed.owl	iron incorporation into metallo-sulphur cluster													biological_process											owl:Class	
GO:0016226	biolink:NamedThing	iron-sulfur cluster assembly	The incorporation of iron and exogenous sulfur into a metallo-sulfur cluster.	tmpzr1t_l9r_go_relaxed.owl	iron-sulfur cluster biosynthesis|iron-sulphur cluster assembly													biological_process											owl:Class	
GO:0033246	biolink:NamedThing	positive regulation of penicillin metabolic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving any antibiotic that contains the condensed beta-lactamthiazolidine ring system.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of penicillin metabolism													biological_process											owl:Class	
GO:0034250	biolink:NamedThing	positive regulation of cellular amide metabolic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving amides.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of amide metabolism													biological_process											owl:Class	
GO:0047050	biolink:NamedThing	(S)-2-hydroxy-fatty acid dehydrogenase activity	Catalysis of the reaction: (S)-2-hydroxystearate + NAD(+) = 2-oxostearate + H(+) + NADH.	tmpzr1t_l9r_go_relaxed.owl	L-2-hydroxy fatty acid dehydrogenase activity|2-hydroxy fatty acid oxidase|(S)-2-hydroxystearate:NAD+ oxidoreductase activity|dehydrogenase, L-2-hydroxy fatty acid|(S)-2-hydroxy-fatty-acid dehydrogenase activity				MetaCyc:1.1.1.99-RXN|KEGG_REACTION:R03022|RHEA:11384|EC:1.1.1.99									molecular_function											owl:Class	
GO:2000831	biolink:NamedThing	regulation of steroid hormone secretion	Any process that modulates the frequency, rate or extent of steroid hormone secretion.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-07-26T08:38:46Z					biological_process											owl:Class	
GO:0097155	biolink:NamedThing	fasciculation of sensory neuron axon	The collection of sensory neuron axons into a bundle of rods, known as a fascicle.	tmpzr1t_l9r_go_relaxed.owl								pr	2011-09-16T09:17:34Z					biological_process											owl:Class	
GO:0007413	biolink:NamedThing	axonal fasciculation	The collection of axons into a bundle of rods, known as a fascicle.	tmpzr1t_l9r_go_relaxed.owl	fasciculation of neuron													biological_process											owl:Class	
GO:0070849	biolink:NamedThing	response to epidermal growth factor	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an epidermal growth factor stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to EGF stimulus|response to epidermal growth factor stimulus							mah	2009-08-04T04:26:26Z					biological_process											owl:Class	
GO:0070848	biolink:NamedThing	response to growth factor	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth factor stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to growth factor stimulus							mah	2009-08-04T04:24:18Z					biological_process											owl:Class	
GO:0032411	biolink:NamedThing	positive regulation of transporter activity	Any process that activates or increases the activity of a transporter.	tmpzr1t_l9r_go_relaxed.owl	up regulation of transporter activity|upregulation of transporter activity|up-regulation of transporter activity|activation of transporter activity|stimulation of transporter activity													biological_process											owl:Class	
GO:0032409	biolink:NamedThing	regulation of transporter activity	Any process that modulates the activity of a transporter.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1905931	biolink:NamedThing	negative regulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching	Any process that stops, prevents or reduces the frequency, rate or extent of vascular smooth muscle cell differentiation involved in phenotypic switching.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of vascular associated smooth muscle cell differentiation involved in phenotypic dimorphism|down regulation of VSMC differentiation involved in phenotypic dimorphism|inhibition of vascular associated smooth muscle cell differentiation involved in phenotypic switching|down regulation of vascular associated smooth muscle cell differentiation involved in phenotypic dimorphism|negative regulation of VSMC differentiation involved in phenotypic dimorphism|down-regulation of VSMC differentiation involved in phenotypic dimorphism|downregulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching|down-regulation of vascular smooth muscle cell differentiation involved in phenotypic switching|inhibition of vascular smooth muscle cell differentiation involved in phenotypic dimorphism|down-regulation of vascular smooth muscle cell differentiation involved in phenotypic dimorphism|down regulation of VSMC differentiation involved in phenotypic switching|downregulation of vascular smooth muscle cell differentiation involved in phenotypic switching|inhibition of VSMC differentiation involved in phenotypic switching|inhibition of VSMC differentiation involved in phenotypic dimorphism|negative regulation of vascular smooth muscle cell differentiation involved in phenotypic switching|down regulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching|downregulation of vascular associated smooth muscle cell differentiation involved in phenotypic dimorphism|downregulation of VSMC differentiation involved in phenotypic dimorphism|down-regulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching|inhibition of vascular smooth muscle cell differentiation involved in phenotypic switching|negative regulation of vascular smooth muscle cell differentiation involved in phenotypic dimorphism|down regulation of vascular smooth muscle cell differentiation involved in phenotypic switching|down-regulation of vascular associated smooth muscle cell differentiation involved in phenotypic dimorphism|down-regulation of VSMC differentiation involved in phenotypic switching|down regulation of vascular smooth muscle cell differentiation involved in phenotypic dimorphism|inhibition of vascular associated smooth muscle cell differentiation involved in phenotypic dimorphism|downregulation of VSMC differentiation involved in phenotypic switching|downregulation of vascular smooth muscle cell differentiation involved in phenotypic dimorphism|negative regulation of VSMC differentiation involved in phenotypic switching							rph	2017-02-09T09:21:08Z					biological_process											owl:Class	
GO:1905916	biolink:NamedThing	negative regulation of cell differentiation involved in phenotypic switching	Any process that stops, prevents or reduces the frequency, rate or extent of cell differentiation involved in phenotypic switching.	tmpzr1t_l9r_go_relaxed.owl	down regulation of cell differentiation involved in phenotypic switching|inhibition of cell differentiation involved in phenotypic switching|down-regulation of cell differentiation involved in phenotypic switching|downregulation of cell differentiation involved in phenotypic switching							rph	2017-02-08T12:23:23Z					biological_process											owl:Class	
GO:0061686	biolink:NamedThing	hercynylcysteine sulfoxide synthase activity	Catalysis of the reaction: L-cysteine + N-alpha,N-alpha,N-alpha-trimethyl-L-histidine (hercynine) + O2 <=> hercynylcysteine sulfoxide + H2O.	tmpzr1t_l9r_go_relaxed.owl	hercynylcysteine S-oxide synthase|hercynylcysteine sulfoxide synthase	https://github.com/geneontology/go-ontology/issues/11163			RHEA:42704|EC:1.14.99.51			dph	2015-03-06T15:08:51Z					molecular_function											owl:Class	
GO:0016705	biolink:NamedThing	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from each of two donors, and molecular oxygen is reduced or incorporated into a donor.	tmpzr1t_l9r_go_relaxed.owl	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, miscellaneous				EC:1.14.-.-									molecular_function											owl:Class	
GO:0062101	biolink:NamedThing	peptidyl-aspartic acid 3-dioxygenase activity	Catalysis of the reaction: protein L-aspartate + 2-oxoglutarate + O2 = protein 3-hydroxy-L-aspartate + succinate + CO2.	tmpzr1t_l9r_go_relaxed.owl	peptide-aspartate beta-dioxygenase activity|aspartate beta-hydroxylase activity|aspartyl/asparaginyl beta-hydroxylase activity|peptide-L-aspartate,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating) activity|aspartylpeptide beta-dioxygenase activity	https://github.com/geneontology/go-ontology/issues/17842			RHEA:11508|MetaCyc:PEPTIDE-ASPARTATE-BETA-DIOXYGENASE-RXN|EC:1.14.11.16			dph	2018-12-06T14:01:15Z			GO:0004597		molecular_function											owl:Class	
GO:0016706	biolink:NamedThing	2-oxoglutarate-dependent dioxygenase activity	Catalysis of the reaction: A + 2-oxoglutarate + O2 = B + succinate + CO2. This is an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from 2-oxoglutarate and one other donor, and one atom of oxygen is incorporated into each donor.	tmpzr1t_l9r_go_relaxed.owl	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors|2-oxoglutarate dioxygenase activity				EC:1.14.11.-|Reactome:R-HSA-6783455|Reactome:R-HSA-1234164							GO:0010302		molecular_function											owl:Class	
GO:1902681	biolink:NamedThing	regulation of replication fork arrest at rDNA repeats	Any process that modulates the frequency, rate or extent of replication fork arrest at rDNA repeats.	tmpzr1t_l9r_go_relaxed.owl	regulation of replication fork blocking at rDNA repeats|regulation of replication fork arrest at ribosomal DNA repeats							mah	2014-02-05T16:59:21Z					biological_process											owl:Class	
GO:0090329	biolink:NamedThing	regulation of DNA-dependent DNA replication	Any process that modulates the rate, frequency, or extent of DNA-dependent DNA replication, the process in which new strands of DNA are synthesized, using parental DNA as a template for the DNA-dependent DNA polymerases that synthesize the new strands.	tmpzr1t_l9r_go_relaxed.owl								tb	2010-05-14T10:42:04Z					biological_process											owl:Class	
GO:0035515	biolink:NamedThing	oxidative RNA demethylase activity	Catalysis of the removal of a methyl group from one or more nucleosides within a RNA molecule involving the oxidation (i.e. electron loss) of one or more atoms.	tmpzr1t_l9r_go_relaxed.owl	2-oxoglutarate-dependent RNA demethylase	https://github.com/geneontology/go-ontology/issues/21160			Reactome:R-HSA-8857692			bf	2010-04-30T02:37:08Z					molecular_function											owl:Class	
GO:1905932	biolink:NamedThing	positive regulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching	Any process that activates or increases the frequency, rate or extent of vascular smooth muscle cell differentiation involved in phenotypic switching.	tmpzr1t_l9r_go_relaxed.owl	activation of vascular associated smooth muscle cell differentiation involved in phenotypic switching|up regulation of vascular associated smooth muscle cell differentiation involved in phenotypic dimorphism|upregulation of VSMC differentiation involved in phenotypic dimorphism|positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching|activation of VSMC differentiation involved in phenotypic dimorphism|up-regulation of VSMC differentiation involved in phenotypic dimorphism|upregulation of vascular smooth muscle cell differentiation involved in phenotypic dimorphism|up-regulation of vascular associated smooth muscle cell differentiation involved in phenotypic dimorphism|up regulation of VSMC differentiation involved in phenotypic switching|up-regulation of VSMC differentiation involved in phenotypic switching|activation of vascular smooth muscle cell differentiation involved in phenotypic switching|upregulation of VSMC differentiation involved in phenotypic switching|positive regulation of VSMC differentiation involved in phenotypic dimorphism|positive regulation of VSMC differentiation involved in phenotypic switching|upregulation of vascular associated smooth muscle cell differentiation involved in phenotypic dimorphism|activation of VSMC differentiation involved in phenotypic switching|upregulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching|up-regulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching|positive regulation of vascular smooth muscle cell differentiation involved in phenotypic dimorphism|up regulation of vascular smooth muscle cell differentiation involved in phenotypic switching|up regulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching|up-regulation of vascular smooth muscle cell differentiation involved in phenotypic dimorphism|up regulation of vascular smooth muscle cell differentiation involved in phenotypic dimorphism|activation of vascular associated smooth muscle cell differentiation involved in phenotypic dimorphism|upregulation of vascular smooth muscle cell differentiation involved in phenotypic switching|positive regulation of vascular associated smooth muscle cell differentiation involved in phenotypic dimorphism|up-regulation of vascular smooth muscle cell differentiation involved in phenotypic switching|up regulation of VSMC differentiation involved in phenotypic dimorphism|activation of vascular smooth muscle cell differentiation involved in phenotypic dimorphism							rph	2017-02-09T09:21:17Z					biological_process											owl:Class	
GO:1905065	biolink:NamedThing	positive regulation of vascular associated smooth muscle cell differentiation	Any process that activates or increases the frequency, rate or extent of vascular smooth muscle cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of vascular smooth muscle cell differentiation|upregulation of vascular associated smooth muscle cell differentiation|up regulation of vascular smooth muscle cell differentiation|up-regulation of vascular associated smooth muscle cell differentiation|up-regulation of VSMC differentiation|positive regulation of vascular smooth muscle cell differentiation|up regulation of vascular associated smooth muscle cell differentiation|activation of vascular smooth muscle cell differentiation|activation of vascular associated smooth muscle cell differentiation|upregulation of VSMC differentiation|upregulation of vascular smooth muscle cell differentiation|up regulation of VSMC differentiation|activation of VSMC differentiation|positive regulation of VSMC differentiation							rph	2016-03-21T11:15:13Z					biological_process											owl:Class	
GO:0034037	biolink:NamedThing	purine ribonucleoside bisphosphate catabolic process	The chemical reactions and pathways resulting in the breakdown of a purine ribonucleoside bisphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar.	tmpzr1t_l9r_go_relaxed.owl	purine ribonucleoside bisphosphate breakdown|purine ribonucleoside bisphosphate catabolism|purine ribonucleoside bisphosphate degradation													biological_process											owl:Class	
GO:0034034	biolink:NamedThing	purine nucleoside bisphosphate catabolic process	The chemical reactions and pathways resulting in the breakdown of a purine nucleoside bisphosphate, a compound consisting of a purine base linked to a deoxyribose or ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar.	tmpzr1t_l9r_go_relaxed.owl	purine nucleoside bisphosphate breakdown|purine nucleoside bisphosphate catabolism|purine nucleoside bisphosphate degradation													biological_process											owl:Class	
GO:0106082	biolink:NamedThing	sucrose import across plasma membrane	The directed movement of sucrose from outside of a cell, across the plasma membrane and into the cytosol.	tmpzr1t_l9r_go_relaxed.owl								hjd	2017-12-28T18:16:29Z					biological_process											owl:Class	
GO:0098704	biolink:NamedThing	carbohydrate import across plasma membrane	The directed movement of a carbohydrate from outside of a cell, across the plasma membrane and into the cytosol.	tmpzr1t_l9r_go_relaxed.owl	carbohydrate import into cell							pr	2012-05-31T02:45:02Z			GO:0097319		biological_process											owl:Class	
GO:0061257	biolink:NamedThing	mesonephric glomerular visceral epithelial cell development	The process whose specific outcome is the progression of a mesonephric glomerular visceral epithelial cell over time, from its formation to the mature structure. A mesonephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the mesonephros.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-08-30T02:10:40Z					biological_process											owl:Class	
GO:0072015	biolink:NamedThing	glomerular visceral epithelial cell development	The process whose specific outcome is the progression of a glomerular visceral epithelial cell over time, from its formation to the mature structure. A glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells.	tmpzr1t_l9r_go_relaxed.owl	podocyte development							mah	2010-01-25T02:12:45Z					biological_process											owl:Class	
GO:0031032	biolink:NamedThing	actomyosin structure organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures containing both actin and myosin or paramyosin. The myosin may be organized into filaments.	tmpzr1t_l9r_go_relaxed.owl	actomyosin organization|actomyosin structure organization and biogenesis|actomyosin structure organisation					Note that this term is a child of 'actin cytoskeleton organization and biogenesis ; GO:0030036' because the actin cytoskeleton is defined as actin filaments and associated proteins.								biological_process											owl:Class	
GO:0032698	biolink:NamedThing	negative regulation of interleukin-15 production	Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-15 production.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of interleukin-15 biosynthetic process|downregulation of interleukin-15 production|negative regulation of IL-15 production|down-regulation of interleukin-15 production|inhibition of interleukin-15 production|down regulation of interleukin-15 production											GO:0045373		biological_process											owl:Class	
GO:0001818	biolink:NamedThing	negative regulation of cytokine production	Any process that stops, prevents, or reduces the rate of production of a cytokine.	tmpzr1t_l9r_go_relaxed.owl	down regulation of cytokine production|negative regulation of cytokine formation|negative regulation of cytokine biosynthesis|negative regulation of cytokine secretion|negative regulation of cytokine synthesis|inhibition of cytokine biosynthetic process|down regulation of cytokine biosynthetic process|negative regulation of cytokine anabolism|down-regulation of cytokine production|downregulation of cytokine production|negative regulation of cytokine biosynthetic process|inhibition of cytokine production|downregulation of cytokine biosynthetic process|down-regulation of cytokine biosynthetic process											GO:0050710|GO:0042036		biological_process											owl:Class	
GO:0035639	biolink:NamedThing	purine ribonucleoside triphosphate binding	Binding to a purine ribonucleoside triphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with triphosphate on the sugar.	tmpzr1t_l9r_go_relaxed.owl	purine NTP binding							bf	2011-01-14T02:46:42Z					molecular_function											owl:Class	
GO:1901265	biolink:NamedThing	nucleoside phosphate binding	Binding to nucleoside phosphate.	tmpzr1t_l9r_go_relaxed.owl								bf	2012-08-17T12:59:58Z					molecular_function											owl:Class	
GO:0048529	biolink:NamedThing	magnesium-protoporphyrin IX monomethyl ester (oxidative) cyclase activity	Catalysis of the reaction: magnesium protoporphyrin IX 13-monomethyl ester + 3 NADPH + 3 H+ + 3 O2 = divinylprotochlorophyllide + 3 NADP+ + 5 H2O.	tmpzr1t_l9r_go_relaxed.owl	Mg-protoporphyrin IX monomethyl ester oxidative cyclase activity|Mg-protoporphyrin IX monomethyl ester (oxidative) cyclase activity|magnesium-protoporphyrin-IX 13-monomethyl ester,NADPH:oxygen oxidoreductase (hydroxylating)				EC:1.14.13.81|RHEA:33235									molecular_function											owl:Class	
GO:0099583	biolink:NamedThing	neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration	Any neurotransmitter receptor activity that is involved in regulating the concentration of calcium in the postsynaptic cytosol.	tmpzr1t_l9r_go_relaxed.owl	neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium levels													molecular_function											owl:Class	
GO:0098960	biolink:NamedThing	postsynaptic neurotransmitter receptor activity	Neurotransmitter receptor activity occuring in the postsynaptic membrane during synaptic transmission.	tmpzr1t_l9r_go_relaxed.owl	neurotransmitter receptor activity involved in chemical synaptic transmission													molecular_function											owl:Class	
GO:0051361	biolink:NamedThing	peptide cross-linking via L-lysine 5-imidazolinone glycine	The formation of a fluorescent protein chromophore cross-link from the alpha-carboxyl carbon of residue n, a lysine, to the alpha-amino nitrogen of residue n+2, a glycine, and a dehydration to form a double bond to the alpha-amino nitrogen of residue n+1. This cross-linking is coupled with a dehydrogenation of residue n+1 to form a double bond between the alpha and beta carbons.	tmpzr1t_l9r_go_relaxed.owl	biosynthetic process of protein-protein cross-link via L-lysine 5-imidazolinone glycine|biosynthesis of protein-protein cross-link via L-lysine 5-imidazolinone glycine				RESID:AA0381	See also the biological process term 'peptidyl-tyrosine dehydrogenation ; GO:0018251'.								biological_process											owl:Class	
GO:0018298	biolink:NamedThing	protein-chromophore linkage	The covalent or noncovalent attachment of a chromophore to a protein.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0103044	biolink:NamedThing	ribosomal protein S6 glutamate-glutamate ligase activity	Catalysis of the reaction: L-glutamate + ATP + a [protein] C-terminal L-glutamate = ADP + hydrogenphosphate + H+ + a [protein] with C-terminal alpha-L-glutamate-alpha-L-glutamate.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN0-6726									molecular_function											owl:Class	
GO:0018169	biolink:NamedThing	ribosomal S6-glutamic acid ligase activity	Catalysis of the posttranslational transfer of one or more glutamic acid residues to the C-terminus of ribosomal protein S6.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0102921	biolink:NamedThing	mannosylglycerate synthase activity	Catalysis of the reaction: GDP-alpha-D-mannose + D-glycerate <=> H+ + 2-(alpha-D-mannosyl)-D-glycerate + GDP.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-8849|RHEA:30639|EC:2.4.1.269									molecular_function											owl:Class	
GO:0071797	biolink:NamedThing	LUBAC complex	A ubiquitin ligase complex that catalyzes linear head-to-tail polyubiquitin conjugation on its targets. In human the complex consists of RBCK1, RNF31 and SHARPIN, and has an MW of approximately 600 kDa, suggesting a heteromultimeric assembly of its subunits. LUBAC stands for Linear Ubiquitin Chain Assembly Complex.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-09-02T04:09:55Z					cellular_component											owl:Class	
GO:0000151	biolink:NamedThing	ubiquitin ligase complex	A protein complex that includes a ubiquitin-protein ligase and enables ubiquitin protein ligase activity. The complex also contains other proteins that may confer substrate specificity on the complex.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0006047	biolink:NamedThing	UDP-N-acetylglucosamine metabolic process	The chemical reactions and pathways involving UDP-N-acetylglucosamine, a substance composed of N-acetylglucosamine, a common structural unit of oligosaccharides, in glycosidic linkage with uridine diphosphate.	tmpzr1t_l9r_go_relaxed.owl	UDP-N-acetylglucosamine metabolism													biological_process											owl:Class	
GO:0006793	biolink:NamedThing	phosphorus metabolic process	The chemical reactions and pathways involving the nonmetallic element phosphorus or compounds that contain phosphorus, usually in the form of a phosphate group (PO4).	tmpzr1t_l9r_go_relaxed.owl	phosphorus metabolism													biological_process											owl:Class	
GO:0048578	biolink:NamedThing	positive regulation of long-day photoperiodism, flowering	Any process that activates, maintains or increases long-day photoperiodism, where the response associated with the photoperiodism is flowering. Flowering is defined by the switch from the vegetative to the reproductive phase.	tmpzr1t_l9r_go_relaxed.owl	stimulation of long-day photoperiodism, flowering|up regulation of long-day photoperiodism, flowering|activation of long-day photoperiodism, flowering|upregulation of long-day photoperiodism, flowering|up-regulation of long-day photoperiodism, flowering													biological_process											owl:Class	
GO:0048586	biolink:NamedThing	regulation of long-day photoperiodism, flowering	Any process that modulates the frequency, rate or extent of long-day photoperiodism, where the response associated with the photoperiodism is flowering. Flowering is defined by the switch from the vegetative to the reproductive phase.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1905194	biolink:NamedThing	positive regulation of chloroplast fission	Any process that activates or increases the frequency, rate or extent of chloroplast fission.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of chloroplast division|upregulation of chloroplast fission|up-regulation of chloroplast division|activation of chloroplast fission|up regulation of chloroplast division|activation of chloroplast division|up-regulation of chloroplast fission|up regulation of chloroplast fission|upregulation of chloroplast division					Any process that modulates the rate, frequency or extent of chloroplast fission. Chloroplast fission is the division of a chloroplast within a cell to form two or more separate chloroplast compartments.		lr	2016-05-10T19:07:51Z					biological_process											owl:Class	
GO:1905192	biolink:NamedThing	regulation of chloroplast fission	Any process that modulates the frequency, rate or extent of chloroplast fission.	tmpzr1t_l9r_go_relaxed.owl	regulation of chloroplast division					Any process that modulates the rate, frequency or extent of chloroplast fission. Chloroplast fission is the division of a chloroplast within a cell to form two or more separate chloroplast compartments.		lr	2016-05-10T19:07:34Z					biological_process											owl:Class	
GO:0016453	biolink:NamedThing	C-acetyltransferase activity	Catalysis of the transfer of an acetyl group to a carbon atom on the acceptor molecule.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0016408	biolink:NamedThing	C-acyltransferase activity	Catalysis of the transfer of an acyl group to a carbon atom on the acceptor molecule.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1902914	biolink:NamedThing	regulation of protein polyubiquitination	Any process that modulates the frequency, rate or extent of protein polyubiquitination.	tmpzr1t_l9r_go_relaxed.owl	regulation of protein polyubiquitylation|regulation of polyubiquitin|regulation of protein polyubiquitinylation							di	2014-04-18T22:09:52Z					biological_process											owl:Class	
GO:0150152	biolink:NamedThing	negative regulation of interleukin-17A production	Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-17A production.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of interleukin-17A biosynthetic process							bc	2019-12-11T07:45:24Z					biological_process											owl:Class	
GO:0032700	biolink:NamedThing	negative regulation of interleukin-17 production	Any process that stops, prevents, or reduces the frequency, rate, or extent of production of any member of the interleukin-17 family of cytokines.	tmpzr1t_l9r_go_relaxed.owl	down regulation of interleukin-17 production|negative regulation of interleukin-17 secretion|negative regulation of interleukin-17 biosynthetic process|negative regulation of Cytotoxic T-lymphocyte-associated antigen 8 secretion|inhibition of interleukin-17 production|negative regulation of CTLA-8 production|negative regulation of IL-17 production|downregulation of interleukin-17 production											GO:0045379|GO:1905077		biological_process											owl:Class	
GO:1905627	biolink:NamedThing	regulation of serotonin biosynthetic process	Any process that modulates the frequency, rate or extent of serotonin biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of serotonin formation|regulation of serotonin synthesis|regulation of serotonin biosynthesis|regulation of serotonin anabolism							pad	2016-10-31T14:26:20Z					biological_process											owl:Class	
GO:1903047	biolink:NamedThing	mitotic cell cycle process	A process that is part of the mitotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl								jl	2014-05-22T14:22:34Z					biological_process											owl:Class	
GO:0060588	biolink:NamedThing	negative regulation of lipoprotein lipid oxidation	Any process that decreases the rate, frequency or extent of lipoprotein lipid oxidation. Lipoprotein lipid oxidation is the modification of a lipoprotein by oxidation of the lipid group.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-05-08T02:30:49Z					biological_process											owl:Class	
GO:1902639	biolink:NamedThing	propan-2-ol metabolic process	The chemical reactions and pathways involving propan-2-ol.	tmpzr1t_l9r_go_relaxed.owl	Isopropanol metabolic process|Isopropyl alcohol metabolic process|propan-2-ol metabolism							tt	2014-01-21T13:57:13Z					biological_process											owl:Class	
GO:1902652	biolink:NamedThing	secondary alcohol metabolic process	The chemical reactions and pathways involving secondary alcohol.	tmpzr1t_l9r_go_relaxed.owl	secondary alcohol metabolism							tt	2014-01-22T10:14:52Z					biological_process											owl:Class	
GO:1904036	biolink:NamedThing	negative regulation of epithelial cell apoptotic process	Any process that stops, prevents or reduces the frequency, rate or extent of epithelial cell apoptotic process.	tmpzr1t_l9r_go_relaxed.owl	down regulation of epithelial cell apoptotic process|down-regulation of epithelial cell apoptotic process|negative regulation of epitheliocyte apoptosis|down-regulation of epithelial cell apoptosis|down regulation of epitheliocyte apoptosis|down regulation of epitheliocyte apoptotic process|down-regulation of epitheliocyte apoptosis|downregulation of epithelial cell apoptosis|downregulation of epitheliocyte apoptosis|down regulation of epithelial cell apoptosis|inhibition of epithelial cell apoptotic process|downregulation of epitheliocyte apoptotic process|inhibition of epitheliocyte apoptotic process|down-regulation of epitheliocyte apoptotic process|inhibition of epitheliocyte apoptosis|downregulation of epithelial cell apoptotic process|negative regulation of epitheliocyte apoptotic process|inhibition of epithelial cell apoptosis|negative regulation of epithelial cell apoptosis							sl	2015-03-13T22:05:47Z					biological_process											owl:Class	
GO:1904035	biolink:NamedThing	regulation of epithelial cell apoptotic process	Any process that modulates the frequency, rate or extent of epithelial cell apoptotic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of epitheliocyte apoptosis|regulation of epitheliocyte apoptotic process|regulation of epithelial cell apoptosis							sl	2015-03-13T22:05:41Z					biological_process											owl:Class	
GO:1901149	biolink:NamedThing	salicylic acid binding	Binding to salicylic acid.	tmpzr1t_l9r_go_relaxed.owl	salicylic acid receptor							dhl	2012-07-16T05:26:38Z					molecular_function											owl:Class	
GO:0033293	biolink:NamedThing	monocarboxylic acid binding	Binding to a monocarboxylic acid, any organic acid containing one carboxyl (COOH) group or anion (COO-).	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0044257	biolink:NamedThing	cellular protein catabolic process	The chemical reactions and pathways resulting in the breakdown of a protein by individual cells.	tmpzr1t_l9r_go_relaxed.owl	cellular protein breakdown|cellular protein degradation|cellular protein catabolism													biological_process											owl:Class	
GO:0044265	biolink:NamedThing	cellular macromolecule catabolic process	The chemical reactions and pathways resulting in the breakdown of a macromolecule, any large molecule including proteins, nucleic acids and carbohydrates, as carried out by individual cells.	tmpzr1t_l9r_go_relaxed.owl	cellular biopolymer catabolic process|cellular macromolecule degradation|cellular macromolecule breakdown|cellular macromolecule catabolism											GO:0034962		biological_process											owl:Class	
GO:1900791	biolink:NamedThing	shamixanthone metabolic process	The chemical reactions and pathways involving shamixanthone.	tmpzr1t_l9r_go_relaxed.owl	shamixanthone metabolism							di	2012-06-04T09:40:20Z					biological_process											owl:Class	
GO:0042180	biolink:NamedThing	cellular ketone metabolic process	The chemical reactions and pathways involving any of a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms, as carried out by individual cells. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups.	tmpzr1t_l9r_go_relaxed.owl	ketone metabolism													biological_process											owl:Class	
GO:2000573	biolink:NamedThing	positive regulation of DNA biosynthetic process	Any process that activates or increases the frequency, rate or extent of DNA biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of DNA biosynthesis|positive regulation of DNA formation|positive regulation of DNA anabolism|positive regulation of DNA synthesis							yaf	2011-04-04T10:01:20Z					biological_process											owl:Class	
GO:0010557	biolink:NamedThing	positive regulation of macromolecule biosynthetic process	Any process that increases the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:2001051	biolink:NamedThing	positive regulation of tendon cell differentiation	Any process that activates or increases the frequency, rate or extent of tendon cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of tenocyte differentiation|positive regulation of muscle attachment cell differentiation							yaf	2011-09-01T09:20:42Z					biological_process											owl:Class	
GO:2001049	biolink:NamedThing	regulation of tendon cell differentiation	Any process that modulates the frequency, rate or extent of tendon cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	regulation of muscle attachment cell differentiation|regulation of tenocyte differentiation							yaf	2011-09-01T09:20:32Z					biological_process											owl:Class	
GO:0047542	biolink:NamedThing	2-furoyl-CoA dehydrogenase activity	Catalysis of the reaction: 2-furoyl-CoA + A + H(2)O = 5-hydroxy-2-furoyl-CoA + AH(2) + H(+).	tmpzr1t_l9r_go_relaxed.owl	2-furoyl coenzyme A hydroxylase activity|2-furoyl-CoA:(acceptor) 5-oxidoreductase (hydroxylating)|furoyl-CoA hydroxylase activity|2-furoyl coenzyme A dehydrogenase activity|2-furoyl-CoA:acceptor 5-oxidoreductase (hydroxylating)				MetaCyc:2-FUROYL-COA-DEHYDROGENASE-RXN|RHEA:21480|EC:1.3.99.8|KEGG_REACTION:R02987									molecular_function											owl:Class	
GO:0016627	biolink:NamedThing	oxidoreductase activity, acting on the CH-CH group of donors	Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.	tmpzr1t_l9r_go_relaxed.owl	oxidoreductase activity, acting on the CH-CH group of donors, other acceptors				Reactome:R-HSA-2995334|Reactome:R-HSA-9661710|EC:1.3.-.-									molecular_function											owl:Class	
GO:0034501	biolink:NamedThing	protein localization to kinetochore	Any process in which a protein is transported to, or maintained at, the kinetochore.	tmpzr1t_l9r_go_relaxed.owl	condensin localization to kinetochore|protein localisation to kinetochore													biological_process											owl:Class	
GO:1903083	biolink:NamedThing	protein localization to condensed chromosome	A process in which a protein is transported to, or maintained in, a location within a condensed chromosome.	tmpzr1t_l9r_go_relaxed.owl	protein localisation to condensed chromosome|protein localisation in condensed chromosome|protein localization in condensed chromosome							kmv	2014-05-29T20:31:25Z					biological_process											owl:Class	
GO:0070040	biolink:NamedThing	rRNA (adenine-C2-)-methyltransferase activity	Catalysis of the reaction: 2 S-adenosyl-L-methionine + adenine(2503) in 23S rRNA = S-adenosyl-L-homocysteine + 5'-deoxyadenosine + L-methionine + rRNA containing C2-methyladenine(2503) in 23S rRNA.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-11586|EC:2.1.1.192									molecular_function											owl:Class	
GO:0016433	biolink:NamedThing	rRNA (adenine) methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing methyladenine.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1902869	biolink:NamedThing	regulation of amacrine cell differentiation	Any process that modulates the frequency, rate or extent of amacrine cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	regulation of amacrine neuron differentiation							mr	2014-04-03T15:24:35Z					biological_process											owl:Class	
GO:0045664	biolink:NamedThing	regulation of neuron differentiation	Any process that modulates the frequency, rate or extent of neuron differentiation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1904677	biolink:NamedThing	positive regulation of somatic stem cell division	Any process that activates or increases the frequency, rate or extent of somatic stem cell division.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of somatic stem cell renewal|activation of somatic stem cell renewal|upregulation of somatic stem cell division|up-regulation of somatic stem cell division|up regulation of somatic stem cell division|up-regulation of somatic stem cell renewal|activation of somatic stem cell division|up regulation of somatic stem cell renewal|upregulation of somatic stem cell renewal							rph	2015-09-14T08:47:34Z					biological_process											owl:Class	
GO:0051781	biolink:NamedThing	positive regulation of cell division	Any process that activates or increases the frequency, rate or extent of cell division.	tmpzr1t_l9r_go_relaxed.owl	up regulation of cell division|stimulation of cell division|up-regulation of cell division|activation of cell division|upregulation of cell division													biological_process											owl:Class	
GO:0044307	biolink:NamedThing	dendritic branch	A dendrite arising from another dendrite.	tmpzr1t_l9r_go_relaxed.owl	dendrite branch|secondary dendrite				NIF_Subcellular:sao884265541			jl	2010-02-05T04:18:53Z					cellular_component											owl:Class	
GO:0030425	biolink:NamedThing	dendrite	A neuron projection that has a short, tapering, morphology. Dendrites receive and integrate signals from other neurons or from sensory stimuli, and conduct nerve impulses towards the axon or the cell body. In most neurons, the impulse is conveyed from dendrites to axon via the cell body, but in some types of unipolar neuron, the impulse does not travel via the cell body.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Dendrite|NIF_Subcellular:sao1211023249									cellular_component											owl:Class	
GO:1900282	biolink:NamedThing	regulation of cellobiose catabolic process	Any process that modulates the frequency, rate or extent of cellobiose catabolic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of cellobiose catabolism							tt	2012-04-05T12:28:50Z					biological_process											owl:Class	
GO:2000930	biolink:NamedThing	regulation of cellobiose metabolic process	Any process that modulates the frequency, rate or extent of cellobiose metabolic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of cellobiose metabolism							tt	2011-08-01T12:42:53Z					biological_process											owl:Class	
GO:0032734	biolink:NamedThing	positive regulation of interleukin-11 production	Any process that activates or increases the frequency, rate, or extent of interleukin-11 production.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of IL-11 production|positive regulation of interleukin-11 secretion|stimulation of interleukin-11 production|up regulation of interleukin-11 production|up-regulation of interleukin-11 production|positive regulation of interleukin-11 biosynthetic process|activation of interleukin-11 production|upregulation of interleukin-11 production											GO:0150171|GO:0045365		biological_process											owl:Class	
GO:0032654	biolink:NamedThing	regulation of interleukin-11 production	Any process that modulates the frequency, rate, or extent of interleukin-11 production.	tmpzr1t_l9r_go_relaxed.owl	regulation of interleukin-11 secretion|regulation of interleukin-11 biosynthetic process|regulation of IL-11 production											GO:0045363|GO:0150169		biological_process											owl:Class	
GO:0051099	biolink:NamedThing	positive regulation of binding	Any process that activates or increases the rate or extent of binding, the selective interaction of a molecule with one or more specific sites on another molecule.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of binding|stimulation of binding|up regulation of binding|upregulation of binding|activation of binding													biological_process											owl:Class	
GO:0048865	biolink:NamedThing	stem cell fate commitment	The process in which the developmental fate of a cell becomes restricted such that it will develop into a stem cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0045165	biolink:NamedThing	cell fate commitment	The commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field.	tmpzr1t_l9r_go_relaxed.owl						Note that this term was 'cell fate determination' but the term name was changed to better match its existing definition and the child term 'cell fate determination; GO:0001709' was also created.								biological_process											owl:Class	
GO:1902216	biolink:NamedThing	positive regulation of interleukin-4-mediated signaling pathway	Any process that activates or increases the frequency, rate or extent of interleukin-4-mediated signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	upregulation of interleukin-4-mediated signaling pathway|up-regulation of interleukin-4-mediated signalling pathway|up regulation of IL-4-mediated signaling pathway|up regulation of interleukin-4-mediated signaling pathway|activation of interleukin-4-mediated signalling pathway|up-regulation of IL-4-mediated signaling pathway|upregulation of IL-4-mediated signaling pathway|up regulation of interleukin-4-mediated signalling pathway|upregulation of interleukin-4-mediated signalling pathway|positive regulation of IL-4-mediated signaling pathway|activation of interleukin-4-mediated signaling pathway|up-regulation of interleukin-4-mediated signaling pathway|activation of IL-4-mediated signaling pathway|positive regulation of interleukin-4-mediated signalling pathway							lb	2013-06-12T12:53:20Z					biological_process											owl:Class	
GO:0046089	biolink:NamedThing	cytosine biosynthetic process	The chemical reactions and pathways resulting in the formation of cytosine, 4-amino-2-hydroxypyrimidine, a pyrimidine derivative that is one of the five main bases found in nucleic acids; it occurs widely in cytidine derivatives.	tmpzr1t_l9r_go_relaxed.owl	cytosine synthesis|cytosine anabolism|cytosine formation|cytosine biosynthesis													biological_process											owl:Class	
GO:0019858	biolink:NamedThing	cytosine metabolic process	The chemical reactions and pathways involving cytosine, 4-amino-2-hydroxypyrimidine, a pyrimidine derivative that is one of the five main bases found in nucleic acids; it occurs widely in cytidine derivatives.	tmpzr1t_l9r_go_relaxed.owl	cytosine metabolism													biological_process											owl:Class	
GO:0030777	biolink:NamedThing	(S)-scoulerine 9-O-methyltransferase activity	Catalysis of the reaction: (S)-scoulerine + S-adenosyl-L-methionine(1+) = (S)-tetrahydrocolumbamine + S-adenosyl-L-homocysteine + H(+).	tmpzr1t_l9r_go_relaxed.owl	S-adenosyl-L-methionine:(S)-scoulerine 9-O-methyltransferase activity|S-adenosyl-L-methionine:(S)-scoclaurine 9-O-methyltransferase activity				EC:2.1.1.117|RHEA:23808|KEGG_REACTION:R03835|MetaCyc:2.1.1.117-RXN									molecular_function											owl:Class	
GO:0042862	biolink:NamedThing	achromobactin catabolic process	The chemical reactions and pathways resulting in the breakdown of achromobactin, a citrate siderophore.	tmpzr1t_l9r_go_relaxed.owl	achromobactin degradation|achromobactin breakdown|achromobactin catabolism													biological_process											owl:Class	
GO:1901616	biolink:NamedThing	organic hydroxy compound catabolic process	The chemical reactions and pathways resulting in the breakdown of organic hydroxy compound.	tmpzr1t_l9r_go_relaxed.owl	organic hydroxy compound catabolism|organic hydroxy compound breakdown|organic hydroxy compound degradation							pr	2012-11-13T12:54:31Z					biological_process											owl:Class	
GO:0102900	biolink:NamedThing	dehydroabietadienal hydroxylase activity	Catalysis of the reaction: dehydroabietadienal + NADPH + O2 <=> dehydroabietic acid + NADP + H2O.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-8534									molecular_function											owl:Class	
GO:0018947	biolink:NamedThing	anaerobic organosilicon metabolic process	The chemical reactions and pathways involving organosilicons, organic compounds that contain silicon, in the absence of oxygen.	tmpzr1t_l9r_go_relaxed.owl	anaerobic organosilicone metabolism|anaerobic organosilicone metabolic process|anaerobic organosilicon metabolism				UM-BBD_pathwayID:osi									biological_process											owl:Class	
GO:0018945	biolink:NamedThing	organosilicon metabolic process	The chemical reactions and pathways involving any organosilicon, organic compounds that contain silicon, a nonmetal element analogous to carbon.	tmpzr1t_l9r_go_relaxed.owl	organosilicone metabolic process|organosilicone metabolism|organosilicon metabolism				UM-BBD_pathwayID:osi									biological_process											owl:Class	
GO:0102177	biolink:NamedThing	24-methylenelophenol methyl oxidase activity	Catalysis of the reaction: 24-methylenelophenol + O2 + NADH + H+ <=> 4alpha-hydroxymethyl-ergosta-7,24(241)-dien-3beta-ol + NAD + H2O.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-11930|RHEA:58872|EC:1.14.18.11									molecular_function											owl:Class	
GO:1901389	biolink:NamedThing	negative regulation of transforming growth factor beta activation	Any process that stops, prevents or reduces the frequency, rate or extent of transforming growth factor beta activation.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of TGFB activation|down regulation of TGF-beta activation|down regulation of L-TGF-beta activation|down regulation of TGFB activation|inhibition of TGF-beta activation|negative regulation of TGFbeta activation|negative regulation of TGF-beta activation|down regulation of latent TGF-beta activation|negative regulation of latent TGF-beta activation|down-regulation of transforming growth factor beta activation|downregulation of latent TGF-beta activation|downregulation of transforming growth factor beta activation|down-regulation of TGF-B activation|negative regulation of TGFB activation|inhibition of TGF-B activation|down-regulation of L-TGF-beta activation|downregulation of TGFB activation|downregulation of TGFbeta activation|inhibition of TGFB activation|down-regulation of TGF-beta activation|downregulation of TGF-beta activation|negative regulation of L-TGF-beta activation|down regulation of TGF-B activation|down regulation of TGFbeta activation|down regulation of transforming growth factor beta activation|down-regulation of TGFbeta activation|negative regulation of TGF-B activation|inhibition of L-TGF-beta activation|downregulation of TGF-B activation|inhibition of transforming growth factor beta activation|downregulation of L-TGF-beta activation|down-regulation of latent TGF-beta activation|inhibition of TGFbeta activation|inhibition of latent TGF-beta activation							bf	2012-10-01T10:33:09Z					biological_process											owl:Class	
GO:1901388	biolink:NamedThing	regulation of transforming growth factor beta activation	Any process that modulates the frequency, rate or extent of transforming growth factor beta activation.	tmpzr1t_l9r_go_relaxed.owl	regulation of TGF-B activation|regulation of TGF-beta activation|regulation of TGFB activation|regulation of TGFbeta activation|regulation of L-TGF-beta activation|regulation of latent TGF-beta activation							bf	2012-10-01T10:32:00Z					biological_process											owl:Class	
GO:1902166	biolink:NamedThing	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	Any process that stops, prevents or reduces the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator.	tmpzr1t_l9r_go_relaxed.owl	down regulation of DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis|inhibition of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator|down-regulation of DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis|downregulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator|negative regulation of DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis|inhibition of DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis|downregulation of DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis|down-regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator|down regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator							lb	2013-05-22T12:45:15Z					biological_process											owl:Class	
GO:1902165	biolink:NamedThing	regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	Any process that modulates the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator.	tmpzr1t_l9r_go_relaxed.owl	regulation of DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis							lb	2013-05-22T12:45:10Z					biological_process											owl:Class	
GO:1904639	biolink:NamedThing	cellular response to resveratrol	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a resveratrol stimulus.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-08-31T17:07:44Z					biological_process											owl:Class	
GO:2000588	biolink:NamedThing	positive regulation of platelet-derived growth factor receptor-beta signaling pathway	Any process that activates or increases the frequency, rate or extent of platelet-derived growth factor receptor-beta signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of platelet-derived growth factor receptor-beta signalling pathway|positive regulation of PDGFR-beta signaling pathway|positive regulation of PDGF receptor-beta signaling pathway|positive regulation of betaPDGF receptor signaling pathway							bf	2011-04-07T03:27:58Z					biological_process											owl:Class	
GO:0007053	biolink:NamedThing	spindle assembly involved in male meiosis	The aggregation, arrangement and bonding together of a set of components to form the spindle during a meiotic cell cycle in males. An example of this is found in Drosophila melanogaster.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0019482	biolink:NamedThing	beta-alanine metabolic process	The chemical reactions and pathways involving beta-alanine (3-aminopropanoic acid), an achiral amino acid and an isomer of alanine. It occurs free (e.g. in brain) and in combination (e.g. in pantothenate) but it is not a constituent of proteins.	tmpzr1t_l9r_go_relaxed.owl	beta-alanine metabolism				Wikipedia:Beta-alanine									biological_process											owl:Class	
GO:0006520	biolink:NamedThing	cellular amino acid metabolic process	The chemical reactions and pathways involving amino acids, carboxylic acids containing one or more amino groups, as carried out by individual cells.	tmpzr1t_l9r_go_relaxed.owl	amino acid and derivative metabolism|amino acid metabolic process|cellular amino acid metabolism|cellular amino acid and derivative metabolic process											GO:0006519		biological_process											owl:Class	
GO:1903818	biolink:NamedThing	positive regulation of voltage-gated potassium channel activity	Any process that activates or increases the frequency, rate or extent of voltage-gated potassium channel activity.	tmpzr1t_l9r_go_relaxed.owl	upregulation of voltage gated potassium channel activity|positive regulation of voltage-sensitive potassium channel|activation of voltage-sensitive potassium channel|activation of voltage-dependent potassium channel activity|up-regulation of voltage-gated potassium channel activity|activation of voltage-gated potassium channel activity|activation of voltage gated potassium channel activity|up-regulation of voltage gated potassium channel activity|upregulation of voltage-gated potassium channel activity|up regulation of voltage-sensitive potassium channel|activation of voltage-gated potassium ion channel activity|up regulation of voltage-dependent potassium channel activity|up-regulation of voltage-gated potassium ion channel activity|positive regulation of voltage-gated potassium ion channel activity|upregulation of voltage-gated potassium ion channel activity|upregulation of voltage-dependent potassium channel activity|up-regulation of voltage-dependent potassium channel activity|up regulation of voltage-gated potassium ion channel activity|up regulation of voltage gated potassium channel activity|upregulation of voltage-sensitive potassium channel|positive regulation of voltage-dependent potassium channel activity|positive regulation of voltage gated potassium channel activity|up-regulation of voltage-sensitive potassium channel|up regulation of voltage-gated potassium channel activity							sl	2015-01-16T17:22:18Z					biological_process											owl:Class	
GO:1990665	biolink:NamedThing	AnxA2-p11 complex	A heterotetrameric protein complex comprising two Annexin A2 (AnxA2) monomers and two copies of its binding partner, S100 protein p11 (S100A10).	tmpzr1t_l9r_go_relaxed.owl	AnxA2:S100A10 heterotetramer|(A2.p11)2 complex|AnxA2.p11 complex|Annexin A2-p11 complex|Annexin A2 tetramer|(p11)2.(AnxA2)2 complex							bf	2015-03-02T10:07:42Z					cellular_component											owl:Class	
GO:0006304	biolink:NamedThing	DNA modification	The covalent alteration of one or more nucleotide sites in DNA, resulting in a change in its properties.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0043412	biolink:NamedThing	macromolecule modification	The covalent alteration of one or more monomeric units in a polypeptide, polynucleotide, polysaccharide, or other biological macromolecule, resulting in a change in its properties.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0033673	biolink:NamedThing	negative regulation of kinase activity	Any process that stops, prevents, or reduces the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.	tmpzr1t_l9r_go_relaxed.owl	inhibition of kinase activity|kinase inhibitor|down-regulation of kinase activity|downregulation of kinase activity|down regulation of kinase activity													biological_process											owl:Class	
GO:1904637	biolink:NamedThing	cellular response to ionomycin	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ionomycin stimulus.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-08-31T14:39:25Z					biological_process											owl:Class	
GO:0071398	biolink:NamedThing	cellular response to fatty acid	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fatty acid stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-12-11T04:39:56Z					biological_process											owl:Class	
GO:0060001	biolink:NamedThing	minus-end directed microfilament motor activity	A motor activity that generates movement along a microfilament towards the minus end, driven by ATP hydrolysis. The minus end of an actin filament is the end that does not preferentially add actin monomers.	tmpzr1t_l9r_go_relaxed.owl	minus-end directed actin filament motor activity|minus-end directed actin-filament motor activity|pointed-end directed actin-filament motor activity													molecular_function											owl:Class	
GO:0000146	biolink:NamedThing	microfilament motor activity	A motor activity that generates movement along a microfilament, driven by ATP hydrolysis.	tmpzr1t_l9r_go_relaxed.owl	actin-activated ATPase activity|muscle motor activity|actin-dependent ATPase activity|myosin ATPase activity|actin filament motor activity|actin-filament motor activity	https://github.com/geneontology/go-ontology/issues/20877			Reactome:R-HSA-432237|Reactome:R-HSA-9023171|Reactome:R-HSA-2316352|EC:5.6.1.8							GO:0030898		molecular_function											owl:Class	
GO:0042650	biolink:NamedThing	prothylakoid membrane	The membrane of prothylakoids, underdeveloped thylakoids found in etioplasts, lacking competent photosynthetic membranes.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0055035	biolink:NamedThing	plastid thylakoid membrane	The lipid bilayer membrane of any thylakoid within a plastid.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:1900425	biolink:NamedThing	negative regulation of defense response to bacterium	Any process that stops, prevents or reduces the frequency, rate or extent of defense response to bacterium.	tmpzr1t_l9r_go_relaxed.owl	inhibition of response to pathogenic bacteria (incompatible interaction)|negative regulation of antibacterial peptide activity|negative regulation of defence response to bacterium|inhibition of defence response to pathogenic bacterium, incompatible interaction|down regulation of defence response to bacterium|inhibition of defense response to bacteria|inhibition of resistance response to pathogenic bacteria|downregulation of defence response to bacterium|down-regulation of antibacterial peptide activity|inhibition of defense response to bacterium|negative regulation of defense response to bacteria|down-regulation of defense response to bacterium|down-regulation of defence response to bacteria|downregulation of defense response to bacteria|down-regulation of defence response to bacterium|inhibition of defence response to bacterium|inhibition of defence response to bacteria|downregulation of antibacterial peptide activity|down regulation of defense response to bacteria|inhibition of defence response to pathogenic bacteria, incompatible interaction|inhibition of response to pathogenic bacterium (incompatible interaction)|negative regulation of defense response to bacterium, incompatible interaction|inhibition of defense response to bacterium, incompatible interaction|inhibition of antibacterial peptide activity|downregulation of defence response to bacteria|downregulation of defense response to bacterium|negative regulation of defence response to bacteria|down regulation of antibacterial peptide activity|down-regulation of defense response to bacteria|down regulation of defence response to bacteria|inhibition of resistance response to pathogenic bacterium|down regulation of defense response to bacterium							dhl	2012-04-24T10:12:54Z			GO:1902478		biological_process											owl:Class	
GO:1900424	biolink:NamedThing	regulation of defense response to bacterium	Any process that modulates the frequency, rate or extent of defense response to bacterium.	tmpzr1t_l9r_go_relaxed.owl	regulation of resistance response to pathogenic bacteria|regulation of defence response to bacteria|regulation of resistance response to pathogenic bacterium|regulation of defense response to bacterium, incompatible interaction|regulation of defence response to pathogenic bacterium, incompatible interaction|regulation of antibacterial peptide activity|regulation of defence response to bacterium, incompatible interaction|regulation of defence response to bacterium|regulation of defense response to bacteria|regulation of defence response to pathogenic bacteria, incompatible interaction							dhl	2012-04-24T10:12:43Z			GO:1902477		biological_process											owl:Class	
GO:0036075	biolink:NamedThing	replacement ossification	Ossification that requires the replacement of a preexisting tissue prior to bone tissue formation.	tmpzr1t_l9r_go_relaxed.owl	indirect ossification							bf	2011-12-19T01:53:16Z					biological_process											owl:Class	
GO:0001503	biolink:NamedThing	ossification	The formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone or a bony substance.	tmpzr1t_l9r_go_relaxed.owl	bone formation|osteogenesis|bone biosynthesis				Wikipedia:Ossification	Note that this term does not have a 'developmental process' parent because ossification isn't necessarily developmental, can also occur as part of bone remodeling. Instead use 'ossification involved in bone maturation ; GO:0043931'.								biological_process											owl:Class	
GO:1904296	biolink:NamedThing	negative regulation of osmolarity-sensing cation channel activity	Any process that stops, prevents or reduces the frequency, rate or extent of osmolarity-sensing cation channel activity.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of osmolarity-sensing cation channel activity|down regulation of osmolarity-sensing cation channel activity|downregulation of osmolarity-sensing cation channel activity|inhibition of osmolarity-sensing cation channel activity							sl	2015-06-09T17:35:46Z					biological_process											owl:Class	
GO:0052733	biolink:NamedThing	quinate 3-dehydrogenase (NADP+) activity	Catalysis of the reaction: quinate + NADP+ = 3-dehydroquinate + NADPH + H+.	tmpzr1t_l9r_go_relaxed.owl	quinate:NADP 3-oxidoreductase activity|quinic dehydrogenase activity|quinate:NADP(+) 3-oxidoreductase activity				KEGG_REACTION:R06846|EC:1.1.1.282|RHEA:18425			ai	2011-08-16T04:23:47Z					molecular_function											owl:Class	
GO:0042167	biolink:NamedThing	heme catabolic process	The chemical reactions and pathways resulting in the breakdown of heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring.	tmpzr1t_l9r_go_relaxed.owl	haem catabolic process|heme degradation|haem catabolism|heme breakdown|heme catabolism													biological_process											owl:Class	
GO:0006787	biolink:NamedThing	porphyrin-containing compound catabolic process	The chemical reactions and pathways resulting in the breakdown of any member of a large group of derivatives or analogs of porphyrin. Porphyrin consists of a ring of four pyrrole nuclei linked each to the next at their alpha positions through a methine group.	tmpzr1t_l9r_go_relaxed.owl	porphyrin breakdown|porphyrin catabolic process|porphyrin catabolism|porphyrin degradation													biological_process											owl:Class	
GO:0019402	biolink:NamedThing	galactitol metabolic process	The chemical reactions and pathways involving galactitol, the hexitol derived by the reduction of the aldehyde group of either D- or L-galactose.	tmpzr1t_l9r_go_relaxed.owl	galactitol metabolism													biological_process											owl:Class	
GO:0006059	biolink:NamedThing	hexitol metabolic process	The chemical reactions and pathways involving hexitols, any alditol with a chain of six carbon atoms in the molecule.	tmpzr1t_l9r_go_relaxed.owl	hexitol metabolism|sugar alcohol (hexitol) metabolism|sugar alcohol (hexitol) metabolic process													biological_process											owl:Class	
GO:0033006	biolink:NamedThing	regulation of mast cell activation involved in immune response	Any process that modulates the frequency, rate, or extent of mast cell activation as part of an immune response.	tmpzr1t_l9r_go_relaxed.owl	regulation of mast cell activation during immune response													biological_process											owl:Class	
GO:1902888	biolink:NamedThing	protein localization to astral microtubule	A process in which a protein is transported to, or maintained in, a location within an astral microtubule.	tmpzr1t_l9r_go_relaxed.owl	protein localization in astral microtubule|protein localisation to astral microtubule|protein localisation in astral microtubule							kmv	2014-04-05T21:26:34Z					biological_process											owl:Class	
GO:1902889	biolink:NamedThing	protein localization to spindle microtubule	A process in which a protein is transported to, or maintained in, a location within a spindle microtubule.	tmpzr1t_l9r_go_relaxed.owl	protein localization in spindle microtubule|protein localisation in spindle microtubule|protein localisation to spindle microtubule							kmv	2014-04-05T21:31:39Z					biological_process											owl:Class	
GO:0097293	biolink:NamedThing	XMP biosynthetic process	The chemical reactions and pathways resulting in the formation of XMP, xanthosine monophosphate.	tmpzr1t_l9r_go_relaxed.owl	XMP formation|XMP biosynthesis|XMP anabolism|XMP synthesis							pr	2012-04-26T09:54:13Z					biological_process											owl:Class	
GO:0097292	biolink:NamedThing	XMP metabolic process	The chemical reactions and pathways involving XMP, xanthosine monophosphate.	tmpzr1t_l9r_go_relaxed.owl	XMP metabolism							pr	2012-04-26T09:51:16Z					biological_process											owl:Class	
GO:0035129	biolink:NamedThing	post-embryonic hindlimb morphogenesis	The process, occurring after embryonic development, by which the anatomical structures of the hindlimb are generated and organized.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0035127	biolink:NamedThing	post-embryonic limb morphogenesis	The process, occurring after embryonic development, by which the anatomical structures of the limb are generated and organized. A limb is an appendage of an animal used for locomotion or grasping.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0102326	biolink:NamedThing	2-hydroxy-6-oxo-6-(2,3-dihydroxyphenyl)-hexa-2,4-dienoate hydrolase activity	Catalysis of the reaction: 2-hydroxy-6-oxo-6-(2,3-dihydroxyphenyl)-hexa-2,4-dienoate + H2O <=> 2,3-dihydroxybenzoate + 2-oxopent-4-enoate + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-13171									molecular_function											owl:Class	
GO:0016823	biolink:NamedThing	hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances	Catalysis of the hydrolysis of any acid carbon-carbon bond in a ketonic substance, a substance containing a keto (C=O) group.	tmpzr1t_l9r_go_relaxed.owl					EC:3.7.1.-									molecular_function											owl:Class	
GO:0055131	biolink:NamedThing	C3HC4-type RING finger domain binding	Binding to a C3HC4-type zinc finger domain of a protein. The C3HC4-type zinc finger is a variant of RING finger, is a cysteine-rich domain of 40 to 60 residues that coordinates two zinc ions, and has the consensus sequence: C-X2-C-X(9-39)-C-X(1-3)-H-X(2-3)-C-X2-C-X(4-48)-C-X2-C, where X is any amino acid. Many proteins containing a C3HC4-type RING finger play a key role in the ubiquitination pathway.	tmpzr1t_l9r_go_relaxed.owl								jid	2009-10-22T02:20:33Z					molecular_function											owl:Class	
GO:2001310	biolink:NamedThing	gliotoxin biosynthetic process	The chemical reactions and pathways resulting in the formation of the epipolythiodioxopiperazine gliotoxin, a poisonous substance produced by some species of fungi.	tmpzr1t_l9r_go_relaxed.owl	gliotoxin formation|gliotoxin anabolism|gliotoxin synthesis|gliotoxin biosynthesis							pr	2012-03-15T03:42:18Z					biological_process											owl:Class	
GO:1902897	biolink:NamedThing	regulation of postsynaptic density protein 95 clustering	Any process that modulates the frequency, rate or extent of postsynaptic density protein 95 clustering.	tmpzr1t_l9r_go_relaxed.owl	regulation of PSD-95 clustering|regulation of post-synaptic density protein 95 clustering|regulation of Dlg4 clustering							als	2014-04-09T14:52:08Z					biological_process											owl:Class	
GO:1905874	biolink:NamedThing	regulation of postsynaptic density organization	Any process that modulates the frequency, rate or extent of postsynaptic density organization.	tmpzr1t_l9r_go_relaxed.owl	regulation of post-synaptic density organization|regulation of post synaptic density organization|regulation of PSD organization|regulation of postsynaptic density organisation							sl	2017-01-27T19:53:32Z					biological_process											owl:Class	
GO:1900979	biolink:NamedThing	positive regulation of tatiopterin metabolic process	Any process that activates or increases the frequency, rate or extent of tatiopterin metabolic process.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of tatiopterin metabolism|up-regulation of tatiopterin metabolism|upregulation of tatiopterin metabolism|up-regulation of tatiopterin metabolic process|up regulation of tatiopterin metabolism|upregulation of tatiopterin metabolic process|activation of tatiopterin metabolic process|activation of tatiopterin metabolism|up regulation of tatiopterin metabolic process							tt	2012-06-14T04:03:37Z					biological_process											owl:Class	
GO:0062013	biolink:NamedThing	positive regulation of small molecule metabolic process	Any process that activates or increases the frequency, rate or extent of a small molecule metabolic process.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of small molecule metabolism							dph	2018-03-19T14:25:10Z					biological_process											owl:Class	
GO:0090321	biolink:NamedThing	positive regulation of chylomicron remnant clearance	Any process that increases the rate, frequency or extent of chylomicron remnant clearance. Chylomicron clearance is the process in which a chylomicron remnant is removed from the blood via receptor-mediated endocytosis into liver cells and its constituent parts degraded.	tmpzr1t_l9r_go_relaxed.owl								tb	2010-04-30T10:20:26Z					biological_process											owl:Class	
GO:0008808	biolink:NamedThing	cardiolipin synthase activity	Catalysis of the reaction: phosphatidylglycerol + phosphatidylglycerol = diphosphatidylglycerol (cardiolipin) + glycerol.	tmpzr1t_l9r_go_relaxed.owl	diphosphatidylglycerol synthase activity|cardiolipin synthetase 2 activity|cardiolipin synthase 2 activity|cardiolipin synthetase activity				RHEA:31451|MetaCyc:CARDIOLIPSYN-RXN							GO:0043788		molecular_function											owl:Class	
GO:0030572	biolink:NamedThing	phosphatidyltransferase activity	Catalysis of the reaction involving the transfer of a phosphatidate (otherwise known as diacylglycerol 3-phosphosphate) group.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0001117	biolink:NamedThing	protein-DNA-RNA complex disassembly	The disaggregation of a protein-DNA-RNA complex into its constituent components.	tmpzr1t_l9r_go_relaxed.owl								krc	2010-12-03T04:04:07Z					biological_process											owl:Class	
GO:0001115	biolink:NamedThing	protein-DNA-RNA complex subunit organization	Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a protein-DNA-RNA complex.	tmpzr1t_l9r_go_relaxed.owl	protein-DNA-RNA complex subunit organisation							krc	2010-12-03T04:00:02Z					biological_process											owl:Class	
GO:0002735	biolink:NamedThing	positive regulation of myeloid dendritic cell cytokine production	Any process that activates or increases the frequency, rate, or extent of myeloid dendritic cell cytokine production.	tmpzr1t_l9r_go_relaxed.owl	up regulation of myeloid dendritic cell cytokine production|stimulation of myeloid dendritic cell cytokine production|activation of myeloid dendritic cell cytokine production|upregulation of myeloid dendritic cell cytokine production|up-regulation of myeloid dendritic cell cytokine production													biological_process											owl:Class	
GO:0009163	biolink:NamedThing	nucleoside biosynthetic process	The chemical reactions and pathways resulting in the formation of any one of a family of organic molecules consisting of a purine or pyrimidine base covalently bonded to a sugar ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside).	tmpzr1t_l9r_go_relaxed.owl	nucleoside formation|nucleoside anabolism|nucleoside synthesis|nucleoside biosynthesis													biological_process											owl:Class	
GO:0034404	biolink:NamedThing	nucleobase-containing small molecule biosynthetic process	The chemical reactions and pathways resulting in the formation of a nucleobase-containing small molecule: a nucleobase, a nucleoside, or a nucleotide.	tmpzr1t_l9r_go_relaxed.owl	nucleobase, nucleoside and nucleotide formation|nucleobase, nucleoside and nucleotide anabolism|nucleobase, nucleoside and nucleotide biosynthesis|nucleobase, nucleoside and nucleotide synthesis													biological_process											owl:Class	
GO:0010936	biolink:NamedThing	negative regulation of macrophage cytokine production	Any process that decreases the rate, frequency or extent of macrophage cytokine production. Macrophage cytokine production is the appearance of a chemokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0002719	biolink:NamedThing	negative regulation of cytokine production involved in immune response	Any process that stops, prevents, or reduces the frequency, rate, or extent of cytokine production contributing to an immune response.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of cytokine biosynthetic process involved in immune response|negative regulation of cytokine secretion involved in immune response|downregulation of cytokine production during immune response|down regulation of cytokine production during immune response|down-regulation of cytokine production during immune response|inhibition of cytokine production during immune response|negative regulation of cytokine production during immune response											GO:0002740|GO:0002743		biological_process											owl:Class	
GO:2000628	biolink:NamedThing	regulation of miRNA metabolic process	Any process that modulates the frequency, rate or extent of miRNA metabolic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of microRNA metabolic process							dph	2011-04-18T03:47:54Z					biological_process											owl:Class	
GO:0051252	biolink:NamedThing	regulation of RNA metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving RNA.	tmpzr1t_l9r_go_relaxed.owl	regulation of RNA metabolism													biological_process											owl:Class	
GO:1990432	biolink:NamedThing	siRNA 3'-end processing	The process of forming the mature 3' end of a siRNA molecule.	tmpzr1t_l9r_go_relaxed.owl	small interfering RNA 3'-end processing|siRNA 3' end processing							jl	2014-07-29T15:38:38Z					biological_process											owl:Class	
GO:0043628	biolink:NamedThing	ncRNA 3'-end processing	Any process involved in forming the mature 3' end of a non-coding RNA molecule.	tmpzr1t_l9r_go_relaxed.owl	ncRNA 3' end processing													biological_process											owl:Class	
GO:0047738	biolink:NamedThing	cellobiose phosphorylase activity	Catalysis of the reaction: cellobiose + phosphate = alpha-D-glucose 1-phosphate + D-glucose.	tmpzr1t_l9r_go_relaxed.owl	cellobiose:phosphate alpha-D-glucosyltransferase activity				EC:2.4.1.20|MetaCyc:CELLOBIOSE-PHOSPHORYLASE-RXN|RHEA:19493									molecular_function											owl:Class	
GO:0004645	biolink:NamedThing	1,4-alpha-oligoglucan phosphorylase activity	Catalysis of the reaction: 1,4-alpha-D-glucosyl(n) + phosphate = 1,4-alpha-D-glucosyl(n-1) + alpha-D-glucose 1-phosphate. The name should be qualified in each instance by adding the name of the natural substrate, e.g. maltodextrin phosphorylase, starch phosphorylase, glycogen phosphorylase.	tmpzr1t_l9r_go_relaxed.owl	polyphosphorylase activity|potato phosphorylase|amylopectin phosphorylase|1,4-alpha-glucan phosphorylase activity|1,4-alpha-D-glucan:phosphate alpha-D-glucosyltransferase activity|alpha-glucan phosphorylase|glucosan phosphorylase|muscle phosphorylase a and b activity|amylophosphorylase activity|muscle phosphorylase|granulose phosphorylase|starch phosphorylase|myophosphorylase|glucan phosphorylase				MetaCyc:RXN-1826|EC:2.4.1.1									molecular_function											owl:Class	
GO:1905637	biolink:NamedThing	regulation of mitochondrial mRNA catabolic process	Any process that modulates the frequency, rate or extent of mitochondrial mRNA catabolic process.	tmpzr1t_l9r_go_relaxed.owl								tb	2016-11-03T20:23:57Z					biological_process											owl:Class	
GO:0140326	biolink:NamedThing	ATPase-coupled intramembrane lipid transporter activity	Catalysis of the movement of lipids from one membrane leaflet to the other, driven by ATP hydrolysis. This includes flippases and floppases.	tmpzr1t_l9r_go_relaxed.owl	aminophospholipid-transporting ATPase|phospholipid flippase activity|phospholipid-transporting ATPase activity|phospholipid translocating ATPase activity|phospholipid-translocating ATPase activity|ATPase-coupled phospholipid transporter activity|ATPase-dependent phospholipid transporter activity	https://github.com/geneontology/go-ontology/issues/17648|https://github.com/geneontology/go-ontology/issues/21612			EC:7.6.2.1|Reactome:R-HSA-939763|MetaCyc:3.6.3.1-RXN|Reactome:R-HSA-947591			pg	2019-04-29T12:42:26Z			GO:0004012|GO:0008557		molecular_function											owl:Class	
GO:0140303	biolink:NamedThing	intramembrane lipid transporter activity	Enables the transport of a lipid from a region of a membrane to a different region on the same membrane.	tmpzr1t_l9r_go_relaxed.owl	flippase activity|translocase activity	https://github.com/geneontology/go-ontology/issues/17648|https://github.com/geneontology/go-ontology/issues/19477						pg	2019-03-01T20:14:09Z					molecular_function											owl:Class	
GO:0050072	biolink:NamedThing	m7G(5')pppN diphosphatase activity	Catalysis of the reaction: 7-methylguanosine 5'-triphospho-5'-polynucleotide + H2O = 7-methylguanosine 5'-phosphate + polynucleotide.	tmpzr1t_l9r_go_relaxed.owl	7-methylguanosine-5'-triphospho-5'-polynucleotide 7-methylguanosine-5'-phosphohydrolase activity|decapase activity|M(7)G(5')pppN pyrophosphatase activity|m7G(5')pppN pyrophosphatase activity				EC:3.6.1.30|MetaCyc:M7G5PPPN-PYROPHOSPHATASE-RXN									molecular_function											owl:Class	
GO:0016462	biolink:NamedThing	pyrophosphatase activity	Catalysis of the hydrolysis of a pyrophosphate bond between two phosphate groups, leaving one phosphate on each of the two fragments.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-6810472									molecular_function											owl:Class	
GO:0018516	biolink:NamedThing	2,4-dichlorobenzoyl-CoA reductase activity	Catalysis of the reaction: 4-chlorobenzoyl-CoA + chloride + NADP(+) = 2,4-dichlorobenzoyl-CoA + NADPH.	tmpzr1t_l9r_go_relaxed.owl	4-chlorobenzoyl-CoA:NADP+ oxidoreductase (halogenating)				RHEA:23076|EC:1.21.1.2|MetaCyc:1.3.1.63-RXN|UM-BBD_reactionID:r0138|KEGG_REACTION:R05276									molecular_function											owl:Class	
GO:0016628	biolink:NamedThing	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces NAD or NADP.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-9661726|EC:1.3.1.-|Reactome:R-HSA-9661745|Reactome:R-HSA-4419979|Reactome:R-HSA-4755572									molecular_function											owl:Class	
GO:0051969	biolink:NamedThing	regulation of transmission of nerve impulse	Any process that modulates the frequency, rate or extent of transmission of a nerve impulse, the sequential electrochemical polarization and depolarization that travels across the membrane of a neuron in response to stimulation.	tmpzr1t_l9r_go_relaxed.owl	regulation of conduction of nerve impulse													biological_process											owl:Class	
GO:0023051	biolink:NamedThing	regulation of signaling	Any process that modulates the frequency, rate or extent of a signaling process.	tmpzr1t_l9r_go_relaxed.owl	regulation of signaling process|regulation of signalling process								2010-02-16T09:30:50Z					biological_process											owl:Class	
GO:0032818	biolink:NamedThing	negative regulation of natural killer cell proliferation	Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer cell proliferation.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of natural killer cell proliferation|negative regulation of NK cell proliferation|downregulation of natural killer cell proliferation|down regulation of natural killer cell proliferation|inhibition of natural killer cell proliferation													biological_process											owl:Class	
GO:1901891	biolink:NamedThing	regulation of cell septum assembly	Any process that modulates the frequency, rate or extent of cell septum assembly.	tmpzr1t_l9r_go_relaxed.owl								tb	2013-02-06T20:14:40Z					biological_process											owl:Class	
GO:0032954	biolink:NamedThing	regulation of cytokinetic process	Any process that modulates the frequency, rate or extent of a cytokinetic process.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0048656	biolink:NamedThing	anther wall tapetum formation	The process that gives rise to the anther wall tapetum. This process pertains to the initial formation of a structure from unspecified parts. The anther wall tapetum is a layer of cells that provides a source of nutrition for the pollen grains as they mature.	tmpzr1t_l9r_go_relaxed.owl	tapetum formation|tapetal layer formation													biological_process											owl:Class	
GO:0048646	biolink:NamedThing	anatomical structure formation involved in morphogenesis	The developmental process pertaining to the initial formation of an anatomical structure from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome.	tmpzr1t_l9r_go_relaxed.owl	formation of an anatomical structure involved in morphogenesis					Note that, for example, the formation of a pseudopod in an amoeba would not be considered formation involved in morphogenesis because it would not be thought of as the formation of an anatomical structure that was part of the shaping of the amoeba during its development. The formation of an axon from a neuron would be considered the formation of an anatomical structure involved in morphogenesis because it contributes to the creation of the form of the neuron in a developmental sense.								biological_process											owl:Class	
GO:0046155	biolink:NamedThing	rhodopsin catabolic process	The chemical reactions and pathways resulting in the breakdown of rhodopsin, a brilliant purplish-red, light-sensitive visual pigment found in the rod cells of the retinas.	tmpzr1t_l9r_go_relaxed.owl	rhodopsin degradation|rhodopsin breakdown|rhodopsin catabolism													biological_process											owl:Class	
GO:0046154	biolink:NamedThing	rhodopsin metabolic process	The chemical reactions and pathways involving rhodopsin, a brilliant purplish-red, light-sensitive visual pigment found in the rod cells of the retinas.	tmpzr1t_l9r_go_relaxed.owl	rhodopsin metabolism													biological_process											owl:Class	
GO:0047253	biolink:NamedThing	alpha-1,6-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity	Catalysis of the reaction: N-acetyl-beta-D-glucosaminyl-1,6-beta-D-(N-acetyl-B-glucosaminyl-1,2)-beta-D-mannosyl-R + UDP-N-acetyl-D-glucosamine = N-acetyl-beta-D-glucosaminyl-1,6-beta-D-(N-acetyl-D-glucosaminyl-1,2-beta)-(N-acetyl-D-glucosaminyl-1,4-beta)-D-mannosyl-R + UDP.	tmpzr1t_l9r_go_relaxed.owl	N-acetylglucosaminyltransferase VI activity|UDP-N-acetyl-D-glucosamine:2,6-bis(N-acetyl-beta-D-glucosaminyl)-alpha-D-mannosyl-glycoprotein 4-beta-N-acetyl-D-glucosaminyltransferase activity|mannosyl-glycoprotein beta-1,4-N-acetylglucosaminyl-transferase activity|alpha-1,6-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase activity|mannosyl-glycoprotein beta-1,4-N-acetylglucosaminyltransferase activity|N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase VI activity|uridine diphosphoacetylglucosamine-glycopeptide beta-1->4-acetylglucosaminyltransferase VI|uridine diphosphoacetylglucosamine-glycopeptide beta-1->4-acetylglucosaminyltransferase VI activity				MetaCyc:2.4.1.201-RXN|RHEA:19945|EC:2.4.1.201									molecular_function											owl:Class	
GO:0140103	biolink:NamedThing	catalytic activity, acting on a glycoprotein	Catalysis of a biochemical reaction at physiological temperatures in which one of the substrates is a glycoprotein.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/14225						pg	2017-09-15T19:27:54Z					molecular_function											owl:Class	
GO:1900246	biolink:NamedThing	positive regulation of RIG-I signaling pathway	Any process that activates or increases the frequency, rate or extent of RIG-I signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	up regulation of RIG-I signaling pathway|up regulation of DDX58 signaling pathway|positive regulation of DDX58 signaling pathway|positive regulation of RIG-I signalling pathway|activation of DDX58 signaling pathway|activation of RIG-I signaling pathway|activation of retinoic acid inducible gene I signaling pathway|up-regulation of RIG-I signaling pathway|up regulation of retinoic acid inducible gene I signaling pathway|up-regulation of retinoic acid inducible gene I signaling pathway|upregulation of retinoic acid inducible gene I signaling pathway|positive regulation of retinoic acid inducible gene I signaling pathway|upregulation of DDX58 signaling pathway|upregulation of RIG-I signaling pathway|up-regulation of DDX58 signaling pathway							ss	2012-04-02T11:00:28Z					biological_process											owl:Class	
GO:0002833	biolink:NamedThing	positive regulation of response to biotic stimulus	Any process that activates or increases the frequency, rate, or extent of a response to biotic stimulus.	tmpzr1t_l9r_go_relaxed.owl	upregulation of response to biotic stimulus|up-regulation of response to biotic stimulus|stimulation of response to biotic stimulus|up regulation of response to biotic stimulus|activation of response to biotic stimulus					Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.								biological_process											owl:Class	
GO:0021761	biolink:NamedThing	limbic system development	The progression of the limbic system over time from its initial formation until its mature state. The limbic system is a collection of structures in the brain involved in emotion, motivation and emotional aspects of memory.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0048731	biolink:NamedThing	system development	The process whose specific outcome is the progression of an organismal system over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0046681	biolink:NamedThing	response to carbamate	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbamate stimulus. Carbamates are a group of insecticides and parasiticides that act by inhibiting cholinesterase.	tmpzr1t_l9r_go_relaxed.owl	carbamate resistance|carbamate susceptibility/resistance													biological_process											owl:Class	
GO:0017085	biolink:NamedThing	response to insecticide	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insecticide stimulus. Insecticides are chemicals used to kill insects.	tmpzr1t_l9r_go_relaxed.owl	insecticide resistance|insecticide susceptibility/resistance													biological_process											owl:Class	
GO:1901520	biolink:NamedThing	aspyridone B catabolic process	The chemical reactions and pathways resulting in the breakdown of aspyridone B.	tmpzr1t_l9r_go_relaxed.owl	aspyridone B degradation|aspyridone B catabolism|aspyridone B breakdown							di	2012-10-18T18:31:44Z					biological_process											owl:Class	
GO:0030640	biolink:NamedThing	polyketide catabolic process	The chemical reactions and pathways resulting in the breakdown of polyketides, any of a diverse group of natural products synthesized via linear poly-beta-ketones, which are themselves formed by repetitive head-to-tail addition of acetyl (or substituted acetyl) units indirectly derived from acetate (or a substituted acetate) by a mechanism similar to that for fatty acid biosynthesis but without the intermediate reductive steps.	tmpzr1t_l9r_go_relaxed.owl	polyketide breakdown|polyketide degradation|polyketide catabolism													biological_process											owl:Class	
GO:1901023	biolink:NamedThing	4-hydroxyphenylacetate catabolic process	The chemical reactions and pathways resulting in the breakdown of 4-hydroxyphenylacetate.	tmpzr1t_l9r_go_relaxed.owl	4-hydroxyphenylacetate breakdown|4-hydroxyphenylacetate catabolism|4-hydroxyphenylacetate degradation							yaf	2012-06-18T02:31:58Z					biological_process											owl:Class	
GO:0070922	biolink:NamedThing	small RNA loading onto RISC	The process in which a single-stranded small RNA associates with the RNA-initiated silencing complex (RISC); occurs as part of a process of gene silencing by small RNA.	tmpzr1t_l9r_go_relaxed.owl	RISC assembly|gene silencing by RNA, small RNA loading onto RISC							mah	2009-09-11T03:57:38Z					biological_process											owl:Class	
GO:0019969	biolink:NamedThing	interleukin-10 binding	Binding to interleukin-10.	tmpzr1t_l9r_go_relaxed.owl	IL-10 binding													molecular_function											owl:Class	
GO:0019838	biolink:NamedThing	growth factor binding	Binding to a growth factor, proteins or polypeptides that stimulate a cell or organism to grow or proliferate.	tmpzr1t_l9r_go_relaxed.owl	neurotrophin TRK receptor activity													molecular_function											owl:Class	
GO:0018870	biolink:NamedThing	anaerobic 2-aminobenzoate metabolic process	The chemical reactions and pathways resulting in the breakdown of 2-aminobenzoate, a derivative of benzoic acid with an NH2 group attached to C2, that occurs in the absence of oxygen.	tmpzr1t_l9r_go_relaxed.owl	anaerobic 2-aminobenzoate metabolism				UM-BBD_pathwayID:abz									biological_process											owl:Class	
GO:0043420	biolink:NamedThing	anthranilate metabolic process	The chemical reactions and pathways involving anthranilate (2-aminobenzoate).	tmpzr1t_l9r_go_relaxed.owl	ortho-aminobenzoic acid metabolic process|2-aminobenzoate metabolic process|ortho-aminobenzoic acid metabolism|anthranilic acid metabolic process|anthranilic acid metabolism|2-aminobenzoate metabolism|anthranilate metabolism				UM-BBD_pathwayID:abz2							GO:0018869		biological_process											owl:Class	
GO:0045938	biolink:NamedThing	positive regulation of circadian sleep/wake cycle, sleep	Any process that activates or increases the duration or quality of sleep, a readily reversible state of reduced awareness and metabolic activity that occurs periodically in many animals.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of circadian sleep/wake cycle, sleep|activation of circadian sleep/wake cycle, sleep|up regulation of circadian sleep/wake cycle, sleep|upregulation of circadian sleep/wake cycle, sleep|positive regulation of sleep|stimulation of circadian sleep/wake cycle, sleep													biological_process											owl:Class	
GO:0045187	biolink:NamedThing	regulation of circadian sleep/wake cycle, sleep	Any process that modulates the frequency, rate or extent of sleep; a readily reversible state of reduced awareness and metabolic activity that occurs periodically in many animals.	tmpzr1t_l9r_go_relaxed.owl	regulation of sleep													biological_process											owl:Class	
GO:1901054	biolink:NamedThing	sarcosine biosynthetic process	The chemical reactions and pathways resulting in the formation of sarcosine.	tmpzr1t_l9r_go_relaxed.owl	sarcosine biosynthesis|sarcosine formation|sarcosine anabolism|sarcosine synthesis							yaf	2012-06-28T04:52:37Z					biological_process											owl:Class	
GO:0042398	biolink:NamedThing	cellular modified amino acid biosynthetic process	The chemical reactions and pathways resulting in the formation of compounds derived from amino acids, organic acids containing one or more amino substituents.	tmpzr1t_l9r_go_relaxed.owl	cellular amino acid derivative anabolism|cellular modified amino acid synthesis|cellular modified amino acid biosynthesis|cellular amino acid derivative synthesis|cellular amino acid derivative biosynthesis|amino acid derivative biosynthetic process|cellular amino acid derivative biosynthetic process|cellular amino acid derivative formation|cellular modified amino acid anabolism|cellular modified amino acid formation													biological_process											owl:Class	
GO:0099015	biolink:NamedThing	degradation of host chromosome by virus	The catabolic breakdown of the DNA of a host chromosome by a virus.  This occurs during infection of bacteria by some phages.  It frees up a large pool of nucleoside 5'-triphophates for use in viral DNA synthesis.	tmpzr1t_l9r_go_relaxed.owl					VZ:3947									biological_process											owl:Class	
GO:0039637	biolink:NamedThing	catabolism by virus of host DNA	The breakdown of host DNA, deoxyribonucleic acid, by a virus.	tmpzr1t_l9r_go_relaxed.owl								bf	2012-08-10T15:59:22Z					biological_process											owl:Class	
GO:0045978	biolink:NamedThing	negative regulation of nucleoside metabolic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving nucleosides.	tmpzr1t_l9r_go_relaxed.owl	down regulation of nucleoside metabolic process|downregulation of nucleoside metabolic process|negative regulation of nucleoside metabolism|inhibition of nucleoside metabolic process|down-regulation of nucleoside metabolic process													biological_process											owl:Class	
GO:0045934	biolink:NamedThing	negative regulation of nucleobase-containing compound metabolic process	Any cellular process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process|negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism|downregulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process|inhibition of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process|down regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process|negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process													biological_process											owl:Class	
GO:1904840	biolink:NamedThing	positive regulation of male germ-line stem cell asymmetric division	Any process that activates or increases the frequency, rate or extent of male germ-line stem cell asymmetric division.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of male germ-line stem cell renewal|up regulation of male germ-line stem cell asymmetric division|activation of male germ-line stem cell asymmetric division|activation of male germ-line stem cell renewal|up-regulation of male germ-line stem cell asymmetric division|up regulation of male germ-line stem cell renewal|up-regulation of male germ-line stem cell renewal|upregulation of male germ-line stem cell asymmetric division|upregulation of male germ-line stem cell renewal							sl	2015-12-05T00:28:46Z					biological_process											owl:Class	
GO:2000243	biolink:NamedThing	positive regulation of reproductive process	Any process that activates or increases the frequency, rate or extent of reproductive process.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-11-10T02:44:08Z					biological_process											owl:Class	
GO:0019622	biolink:NamedThing	3-(3-hydroxy)phenylpropionate catabolic process	The chemical reactions and pathways resulting in the breakdown of 3-(3-hydroxy)phenylpropionate, a hydroxylated derivative of phenylpropionate.	tmpzr1t_l9r_go_relaxed.owl	3-(3-hydroxy)phenylpropionate degradation|3-(3-hydroxy)phenylpropionate catabolism|3-(3-hydroxy)phenylpropionate breakdown				MetaCyc:HCAMHPDEG-PWY									biological_process											owl:Class	
GO:0046435	biolink:NamedThing	3-(3-hydroxy)phenylpropionate metabolic process	The chemical reactions and pathways involving 3-(3-hydroxy)phenylpropionate, a hydroxylated derivative of phenylpropionate.	tmpzr1t_l9r_go_relaxed.owl	3-(3-hydroxy)phenylpropionate metabolism													biological_process											owl:Class	
GO:0046752	biolink:NamedThing	viral capsid precursor transport to host cell nucleus	Any process in which viral capsid precursors are transported to a specific location in the nucleus, thus accumulating the necessary components for assembly of a capsid.	tmpzr1t_l9r_go_relaxed.owl	viral capsid precursor localization in host cell nucleus|localization of viral capsid precursors in nucleus|establishment and maintenance of viral capsid precursor localization in nucleus|viral capsid precursor localisation in host cell nucleus|viral capsid precursor localization to host cell nucleus|nuclear localization of viral capsid precursors													biological_process											owl:Class	
GO:0030581	biolink:NamedThing	symbiont intracellular protein transport in host	The directed movement of a symbiont's proteins within a cell of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	intracellular protein transport in host|intracellular protein transport in other organism involved in symbiotic interaction|intracellular protein transport in other organism during symbiotic interaction|host cell protein transport											GO:0051708		biological_process											owl:Class	
GO:0061223	biolink:NamedThing	mesonephric mesenchymal cell differentiation	The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesenchymal cells of the mesonephros as it progresses from its formation to the mature state.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-08-19T01:21:48Z					biological_process											owl:Class	
GO:0061208	biolink:NamedThing	cell differentiation involved in mesonephros development	The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the mesonephros as it progresses from its formation to the mature state.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-08-17T03:21:23Z					biological_process											owl:Class	
GO:0009131	biolink:NamedThing	pyrimidine nucleoside monophosphate catabolic process	The chemical reactions and pathways resulting in the breakdown of pyrimidine nucleoside monophosphate, a compound consisting of a pyrimidine base linked to a ribose or deoxyribose sugar esterified with phosphate on the sugar.	tmpzr1t_l9r_go_relaxed.owl	pyrimidine nucleoside monophosphate breakdown|pyrimidine nucleoside monophosphate catabolism|pyrimidine nucleoside monophosphate degradation													biological_process											owl:Class	
GO:0009125	biolink:NamedThing	nucleoside monophosphate catabolic process	The chemical reactions and pathways resulting in the breakdown of a nucleoside monophosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with phosphate on the sugar.	tmpzr1t_l9r_go_relaxed.owl	nucleoside monophosphate breakdown|nucleoside monophosphate catabolism|nucleoside monophosphate degradation													biological_process											owl:Class	
GO:0021965	biolink:NamedThing	spinal cord ventral commissure morphogenesis	The process in which the anatomical structures of the spinal cord ventral commissure are generated and organized.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0021952	biolink:NamedThing	central nervous system projection neuron axonogenesis	Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body towards target cells in a different central nervous system region.	tmpzr1t_l9r_go_relaxed.owl	central nervous system axon tract development													biological_process											owl:Class	
GO:0033209	biolink:NamedThing	tumor necrosis factor-mediated signaling pathway	A series of molecular signals initiated by the binding of a tumor necrosis factor to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.	tmpzr1t_l9r_go_relaxed.owl	adipocytokine signaling pathway|TNF-alpha-mediated signaling pathway|tumor necrosis factor-mediated signalling pathway|tumor necrosis factor alpha-mediated signaling pathway													biological_process											owl:Class	
GO:0019221	biolink:NamedThing	cytokine-mediated signaling pathway	A series of molecular signals initiated by the binding of a cytokine to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.	tmpzr1t_l9r_go_relaxed.owl	cytokine and chemokine mediated signaling pathway|cytokine mediated signalling pathway													biological_process											owl:Class	
GO:1990858	biolink:NamedThing	cellular response to lectin	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lectin stimulus. A lectin is a carbohydrate-binding protein, highly specific for binding sugar moieties.	tmpzr1t_l9r_go_relaxed.owl						This term refers to endogenous (evolved) responses to lectins (endogenous or exogenous), it does not cover the events that happen due to lectin toxicity.		sl	2015-09-24T15:34:42Z					biological_process											owl:Class	
GO:1990840	biolink:NamedThing	response to lectin	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lectin stimulus. A lectin is a carbohydrate-binding protein, highly specific for binding sugar moieties.	tmpzr1t_l9r_go_relaxed.owl						This term refers to endogenous (evolved) responses to lectins (endogenous or exogenous), it does not cover the events that happen due to lectin toxicity.		sl	2015-08-27T20:02:21Z					biological_process											owl:Class	
GO:1990072	biolink:NamedThing	TRAPPIII protein complex	A complex that functions in anterograde transport at the Golgi and also regulates autophagy. In yeast it includes at least the following subunits: Bet3 (as homodimer), Bet5, Trs20, Trs23, Trs31, Trs33, Trs85. TRAPPIII may include further, as yet undescribed, proteins.	tmpzr1t_l9r_go_relaxed.owl								bhm	2013-03-28T14:28:59Z					cellular_component											owl:Class	
GO:0030008	biolink:NamedThing	TRAPP complex	A large complex that acts as a tethering factor involved in transporting vesicles from the ER through the Golgi to the plasma membrane. A TRAPP (transport protein particle) complex has a core set of proteins which are joined by specific subunits depending on the cellular component where a given TRAPP complex is active.	tmpzr1t_l9r_go_relaxed.owl	transport protein particle|TRAPP1|transport protein particle complex|TRAPP2				Wikipedia:TRAPP_complex									cellular_component											owl:Class	
GO:1990362	biolink:NamedThing	butanol dehydrogenase activity	Catalysis of the reaction: butanal + NADH + H+ => n-butanol + NAD+.	tmpzr1t_l9r_go_relaxed.owl					RHEA:33199			tt	2014-04-23T21:14:09Z					molecular_function											owl:Class	
GO:0004022	biolink:NamedThing	alcohol dehydrogenase (NAD+) activity	Catalysis of the reaction: an alcohol + NAD+ = an aldehyde or ketone + NADH + H+.	tmpzr1t_l9r_go_relaxed.owl	aldo-keto reductase (NAD) activity|primary alcohol dehydrogenase|alcohol dehydrogenase activity|NADH-alcohol dehydrogenase|NAD-specific aromatic alcohol dehydrogenase|NADH-aldehyde dehydrogenase|yeast alcohol dehydrogenase|alcohol:NAD+ oxidoreductase|aldehyde dehydrogenase (NAD) activity|NAD-dependent alcohol dehydrogenase|aliphatic alcohol dehydrogenase|ethanol dehydrogenase|ADH				UM-BBD_enzymeID:e0023|RHEA:10740|Reactome:R-HSA-2162078|MetaCyc:ALCOHOL-DEHYDROG-GENERIC-RXN|EC:1.1.1.1									molecular_function											owl:Class	
GO:0002584	biolink:NamedThing	negative regulation of antigen processing and presentation of peptide antigen	Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of peptide antigen.	tmpzr1t_l9r_go_relaxed.owl	down regulation of antigen processing and presentation of peptide antigen|down-regulation of antigen processing and presentation of peptide antigen|negative regulation of peptide antigen processing and presentation|inhibition of antigen processing and presentation of peptide antigen|downregulation of antigen processing and presentation of peptide antigen													biological_process											owl:Class	
GO:0007041	biolink:NamedThing	lysosomal transport	The directed movement of substances into, out of or within a lysosome.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0007034	biolink:NamedThing	vacuolar transport	The directed movement of substances into, out of or within a vacuole.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1901641	biolink:NamedThing	ITP binding	Binding to ITP.	tmpzr1t_l9r_go_relaxed.owl								tb	2012-11-15T22:56:39Z					molecular_function											owl:Class	
GO:0032555	biolink:NamedThing	purine ribonucleotide binding	Binding to a purine ribonucleotide, any compound consisting of a purine ribonucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose moiety.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0010899	biolink:NamedThing	regulation of phosphatidylcholine catabolic process	Any process that modulates the rate, frequency or extent of phosphatidylcholine catabolism. Phosphatidylcholine catabolic processes are the chemical reactions and pathways resulting in the breakdown of phosphatidylcholines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of choline.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0150172	biolink:NamedThing	regulation of phosphatidylcholine metabolic process	Any process that modulates the frequency, rate or extent of phosphatidylcholine metabolic process.	tmpzr1t_l9r_go_relaxed.owl								bc	2020-01-21T14:03:11Z					biological_process											owl:Class	
GO:0032395	biolink:NamedThing	MHC class II receptor activity	Combining with an MHC class II protein complex and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	T cell receptor activity|alpha-beta T cell receptor activity|gamma-delta T cell receptor activity					Note that this term is intended for annotation of gene products that act as receptors for MHC class II protein complexes, not for components of the MHC class II protein complexes themselves.								molecular_function											owl:Class	
GO:0150065	biolink:NamedThing	regulation of deacetylase activity	Any process that modulates the frequency, rate or extent of deacetylase activity.	tmpzr1t_l9r_go_relaxed.owl								bc	2018-07-23T12:24:28Z					biological_process											owl:Class	
GO:0051336	biolink:NamedThing	regulation of hydrolase activity	Any process that modulates the frequency, rate or extent of hydrolase activity, the catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3.	tmpzr1t_l9r_go_relaxed.owl	hydrolase regulator													biological_process											owl:Class	
GO:1903967	biolink:NamedThing	response to micafungin	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a micafungin stimulus.	tmpzr1t_l9r_go_relaxed.owl								al	2015-02-27T09:57:38Z					biological_process											owl:Class	
GO:1901652	biolink:NamedThing	response to peptide	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide stimulus.	tmpzr1t_l9r_go_relaxed.owl								pr	2012-11-20T09:45:15Z					biological_process											owl:Class	
GO:2000802	biolink:NamedThing	positive regulation of endocardial cushion to mesenchymal transition involved in heart valve formation	Any process that activates or increases the frequency, rate or extent of endocardial cushion to mesenchymal transition involved in heart valve formation.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of endocardial cushion to mesenchymal transition involved in valve formation							bf	2011-07-01T12:31:25Z					biological_process											owl:Class	
GO:0140051	biolink:NamedThing	positive regulation of endocardial cushion to mesenchymal transition	Any process that activates or increases the frequency, rate or extent of endocardial cushion to mesenchymal transition.	tmpzr1t_l9r_go_relaxed.owl								pg	2017-06-26T09:11:03Z					biological_process											owl:Class	
GO:0071323	biolink:NamedThing	cellular response to chitin	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chitin stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-12-10T05:25:54Z					biological_process											owl:Class	
GO:0071417	biolink:NamedThing	cellular response to organonitrogen compound	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organonitrogen stimulus. An organonitrogen compound is formally a compound containing at least one carbon-nitrogen bond.	tmpzr1t_l9r_go_relaxed.owl	cellular response to organic nitrogen							mah	2009-12-14T04:07:27Z					biological_process											owl:Class	
GO:0052696	biolink:NamedThing	flavonoid glucuronidation	The modification of a flavonoid by the conjugation of glucuronic acid. The resultant flavonoid glucuronosides are often much more water-soluble than the precursor.	tmpzr1t_l9r_go_relaxed.owl	flavonoid glucuronide biosynthetic process|flavonoid glucuronoside biosynthetic process|flavonoid glucuronide biosynthesis|flavonoid glucuronoside biosynthesis							ai	2011-07-27T05:37:44Z					biological_process											owl:Class	
GO:0009812	biolink:NamedThing	flavonoid metabolic process	The chemical reactions and pathways involving flavonoids, a group of water-soluble phenolic derivatives containing a flavan skeleton including flavones, flavonols and flavanoids, and anthocyanins.	tmpzr1t_l9r_go_relaxed.owl	flavonoid metabolism													biological_process											owl:Class	
GO:1905938	biolink:NamedThing	positive regulation of germ cell proliferation	Any process that activates or increases the frequency, rate or extent of germ cell proliferation.	tmpzr1t_l9r_go_relaxed.owl	activation of germ cell proliferation|up regulation of germ cell proliferation|up-regulation of germ cell proliferation|upregulation of germ cell proliferation							hbye	2017-02-09T14:51:51Z					biological_process											owl:Class	
GO:1905936	biolink:NamedThing	regulation of germ cell proliferation	Any process that modulates the frequency, rate or extent of germ cell proliferation.	tmpzr1t_l9r_go_relaxed.owl								hbye	2017-02-09T14:51:31Z					biological_process											owl:Class	
GO:0050586	biolink:NamedThing	3-hydroxy-2-methylquinolin-4-one 2,4-dioxygenase activity	Catalysis of the reaction: 3-hydroxy-2-methylquinolin-4(1H)-one + H(+) + O(2) = N-acetylanthranilate + CO.	tmpzr1t_l9r_go_relaxed.owl	1H-3-hydroxy-4-oxo quinaldine 2,4-dioxygenase activity|3-hydroxy-2-methyl-1H-quinolin-4-one 2,4-dioxygenase (CO-forming)|3-hydroxy-2-methyl-quinolin-4-one 2,4-dioxygenase activity|(1H)-3-hydroxy-4-oxoquinaldine 2,4-dioxygenase activity|1H-3-hydroxy-4-oxoquinaldine 2,4-dioxygenase activity				EC:1.13.11.48|RHEA:21572|MetaCyc:1.13.11.48-RXN|KEGG_REACTION:R05720									molecular_function											owl:Class	
GO:0016702	biolink:NamedThing	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from one donor, and two oxygen atoms is incorporated into a donor.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-2161917|Reactome:R-HSA-9018880|Reactome:R-HSA-5164399|Reactome:R-HSA-9026408|Reactome:R-HSA-2161907|Reactome:R-HSA-9020274|Reactome:R-HSA-9026918|EC:1.13.11.-|Reactome:R-HSA-2161775									molecular_function											owl:Class	
GO:0070094	biolink:NamedThing	positive regulation of glucagon secretion	Any process that activates or increases the frequency, rate or extent of the regulated release of glucagon.	tmpzr1t_l9r_go_relaxed.owl	stimulation of glucagon secretion|up-regulation of glucagon secretion|upregulation of glucagon secretion|activation of glucagon secretion|up regulation of glucagon secretion													biological_process											owl:Class	
GO:0008701	biolink:NamedThing	4-hydroxy-2-oxovalerate aldolase activity	Catalysis of the reaction: 4-hydroxy-2-oxopentanoate = acetaldehyde + pyruvate.	tmpzr1t_l9r_go_relaxed.owl	4-hydroxy-2-oxopentanoate pyruvate-lyase activity|DmpG|4-hydroxy-2-oxopentanoate pyruvate-lyase (acetaldehyde-forming) activity|4-hydroxy-2-ketovalerate aldolase activity|4-hydroxy-2-oxovalerate pyruvate-lyase activity|HOA				UM-BBD_enzymeID:e0077|KEGG_REACTION:R00750|MetaCyc:MHPELY-RXN|RHEA:22624|EC:4.1.3.39							GO:0018804		molecular_function											owl:Class	
GO:0016833	biolink:NamedThing	oxo-acid-lyase activity	Catalysis of the cleavage of a C-C bond by other means than by hydrolysis or oxidation, of a 3-hydroxy acid.	tmpzr1t_l9r_go_relaxed.owl	oxoacid lyase activity|oxo-acid lyase activity				EC:4.1.3.-									molecular_function											owl:Class	
GO:0050303	biolink:NamedThing	lysine 6-dehydrogenase activity	Catalysis of the reaction: H2O + NAD+ + L-lysine = NH3 + NADH + allysine.	tmpzr1t_l9r_go_relaxed.owl	L-lysine:NAD+ 6-oxidoreductase (deaminating)|LysDH activity|L-lysine 6-dehydrogenase activity|L-lysine epsilon-dehydrogenase activity				MetaCyc:LYSINE-6-DEHYDROGENASE-RXN|EC:1.4.1.18|RHEA:12408|MetaCyc:PWY-5314									molecular_function											owl:Class	
GO:0016639	biolink:NamedThing	oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH2 group acts as a hydrogen or electron donor and reduces NAD+ or NADP.	tmpzr1t_l9r_go_relaxed.owl					EC:1.4.1.-									molecular_function											owl:Class	
GO:0043318	biolink:NamedThing	negative regulation of cytotoxic T cell degranulation	Any process that stops, prevents, or reduces the rate of cytotoxic T cell degranulation.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of cytotoxic T-cell granule exocytosis|negative regulation of cytotoxic T-lymphocyte granule exocytosis|down-regulation of cytotoxic T cell degranulation|negative regulation of cytotoxic T cell granule exocytosis|negative regulation of cytotoxic T lymphocyte degranulation|negative regulation of cytotoxic T-cell degranulation|negative regulation of cytotoxic T lymphocyte granule exocytosis|down regulation of cytotoxic T cell degranulation|negative regulation of cytotoxic T-lymphocyte degranulation|inhibition of cytotoxic T cell degranulation|downregulation of cytotoxic T cell degranulation													biological_process											owl:Class	
GO:0043317	biolink:NamedThing	regulation of cytotoxic T cell degranulation	Any process that modulates the frequency, rate, or extent of cytotoxic T cell degranulation.	tmpzr1t_l9r_go_relaxed.owl	regulation of cytotoxic T lymphocyte degranulation|regulation of cytotoxic T-lymphocyte granule exocytosis|regulation of cytotoxic T-cell granule exocytosis|regulation of cytotoxic T-cell degranulation|regulation of cytotoxic T-lymphocyte degranulation|regulation of cytotoxic T cell granule exocytosis|regulation of cytotoxic T lymphocyte granule exocytosis													biological_process											owl:Class	
GO:0071783	biolink:NamedThing	endoplasmic reticulum cisternal network organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endoplasmic reticulum (ER) cisternal network. The ER cisternal network is the ER part that comprises the membranes with low curvature in cross-section.	tmpzr1t_l9r_go_relaxed.owl	ER cisternal network organization|ER cisternal network organisation|endoplasmic reticulum cisternal network organisation							mah	2010-09-01T01:47:28Z					biological_process											owl:Class	
GO:0007029	biolink:NamedThing	endoplasmic reticulum organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endoplasmic reticulum.	tmpzr1t_l9r_go_relaxed.owl	endoplasmic reticulum organization and biogenesis|endoplasmic reticulum morphology|ER organisation|endoplasmic reticulum organisation|ER organization and biogenesis													biological_process											owl:Class	
GO:2000083	biolink:NamedThing	negative regulation of L-ascorbic acid biosynthetic process	Any process that stops, prevents, or reduces the frequency, rate or extent of L-ascorbic acid biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of ascorbate biosynthetic process|negative regulation of vitamin C biosynthetic process|negative regulation of L-ascorbic acid biosynthesis|negative regulation of L-ascorbic acid anabolism|negative regulation of ascorbate biosynthesis|negative regulation of L-ascorbic acid synthesis|negative regulation of L-ascorbic acid formation|negative regulation of vitamin C biosynthesis							tb	2010-08-27T11:26:19Z					biological_process											owl:Class	
GO:0045912	biolink:NamedThing	negative regulation of carbohydrate metabolic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving carbohydrate.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of carbohydrate metabolic process|downregulation of carbohydrate metabolic process|inhibition of carbohydrate metabolic process|negative regulation of carbohydrate metabolism|down regulation of carbohydrate metabolic process													biological_process											owl:Class	
GO:0002458	biolink:NamedThing	peripheral T cell tolerance induction	Tolerance induction of T cells in the periphery, in this case, any location in the body other than the thymus.	tmpzr1t_l9r_go_relaxed.owl	peripheral T-cell tolerance induction|peripheral T-lymphocyte tolerance induction|peripheral T lymphocyte tolerance induction													biological_process											owl:Class	
GO:0002517	biolink:NamedThing	T cell tolerance induction	A process involving any mechanism for tolerance induction in T cells.	tmpzr1t_l9r_go_relaxed.owl	T-cell tolerance induction|T-lymphocyte tolerance induction|T lymphocyte tolerance induction													biological_process											owl:Class	
GO:2000177	biolink:NamedThing	regulation of neural precursor cell proliferation	Any process that modulates the frequency, rate or extent of neural precursor cell proliferation.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-10-13T12:40:41Z					biological_process											owl:Class	
GO:1904712	biolink:NamedThing	positive regulation of Wnt-Frizzled-LRP5/6 complex assembly	Any process that activates or increases the frequency, rate or extent of Wnt-Frizzled-LRP5/6 complex assembly.	tmpzr1t_l9r_go_relaxed.owl	upregulation of WNT-FZD-LRP6 complex formation|up regulation of Frizzled-LRP5/6 complex assembly|positive regulation of WNT-FZD-LRP5 complex formation|upregulation of WNT-FZD-LRP6 complex assembly|activation of Wnt-induced Frizzled-LRP5/6 complex formation|up regulation of Wnt-FZD-LRP5/6 trimeric complex formation|up regulation of WNT-FZD-LRP5 complex assembly|up regulation of WNT-FZD-LRP6 complex formation|up-regulation of Wnt-FZD-LRP5/6 trimeric complex assembly|upregulation of Wnt-induced Frizzled-LRP5/6 complex formation|positive regulation of WNT-FZD-LRP6 complex assembly|upregulation of Wnt-FZD-LRP5/6 trimeric complex assembly|positive regulation of Frizzled-LRP5/6 complex formation|up-regulation of WNT-FZD-LRP5 complex formation|activation of Frizzled-LRP5/6 complex formation|up-regulation of Wnt-induced Frizzled-LRP5/6 complex assembly|activation of Wnt-FZD-LRP5/6 trimeric complex assembly|up regulation of WNT-FZD-LRP5 complex formation|activation of Wnt-induced Frizzled-LRP5/6 complex assembly|positive regulation of Frizzled-LRP5/6 complex assembly|up regulation of Frizzled-LRP5/6 complex formation|positive regulation of Wnt-FZD-LRP5/6 trimeric complex assembly|positive regulation of WNT-FZD-LRP5 complex assembly|activation of WNT-FZD-LRP6 complex formation|upregulation of WNT-FZD-LRP5 complex assembly|activation of Wnt-FZD-LRP5/6 trimeric complex formation|positive regulation of WNT-FZD-LRP6 complex formation|up-regulation of Frizzled-LRP5/6 complex formation|up regulation of Wnt-FZD-LRP5/6 trimeric complex assembly|up-regulation of Frizzled-LRP5/6 complex assembly|up-regulation of Wnt-induced Frizzled-LRP5/6 complex formation|positive regulation of Wnt-FZD-LRP5/6 trimeric complex formation|up-regulation of WNT-FZD-LRP6 complex formation|positive regulation of Wnt-induced Frizzled-LRP5/6 complex formation|up-regulation of WNT-FZD-LRP5 complex assembly|up regulation of Wnt-induced Frizzled-LRP5/6 complex assembly|activation of WNT-FZD-LRP6 complex assembly|up regulation of WNT-FZD-LRP6 complex assembly|up-regulation of Wnt-FZD-LRP5/6 trimeric complex formation|upregulation of Frizzled-LRP5/6 complex formation|upregulation of Wnt-induced Frizzled-LRP5/6 complex assembly|up regulation of Wnt-induced Frizzled-LRP5/6 complex formation|activation of Frizzled-LRP5/6 complex assembly|up-regulation of WNT-FZD-LRP6 complex assembly|activation of WNT-FZD-LRP5 complex assembly|upregulation of WNT-FZD-LRP5 complex formation|upregulation of Frizzled-LRP5/6 complex assembly|activation of WNT-FZD-LRP5 complex formation|positive regulation of Wnt-induced Frizzled-LRP5/6 complex assembly|upregulation of Wnt-FZD-LRP5/6 trimeric complex formation							bf	2015-10-05T14:02:35Z					biological_process											owl:Class	
GO:1904441	biolink:NamedThing	regulation of thyroid gland epithelial cell proliferation	Any process that modulates the frequency, rate or extent of thyroid gland epithelial cell proliferation.	tmpzr1t_l9r_go_relaxed.owl	regulation of thyroid follicular cell proliferation|regulation of Hurthle cell proliferation							sl	2015-07-06T15:41:09Z					biological_process											owl:Class	
GO:0050678	biolink:NamedThing	regulation of epithelial cell proliferation	Any process that modulates the frequency, rate or extent of epithelial cell proliferation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:2000131	biolink:NamedThing	regulation of tyramine signaling pathway	Any process that modulates the frequency, rate or extent of tyramine signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	regulation of tyramine signalling pathway							mah	2010-09-29T09:31:56Z					biological_process											owl:Class	
GO:0050759	biolink:NamedThing	positive regulation of thymidylate synthase biosynthetic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of the enzyme thymidylate synthase.	tmpzr1t_l9r_go_relaxed.owl	up regulation of thymidylate synthase biosynthetic process|positive regulation of thymidylate synthase formation|activation of thymidylate synthase biosynthetic process|positive regulation of thymidylate synthase biosynthesis|up-regulation of thymidylate synthase biosynthetic process|positive regulation of thymidylate synthase synthesis|stimulation of thymidylate synthase biosynthetic process|positive regulation of thymidylate synthase anabolism|upregulation of thymidylate synthase biosynthetic process													biological_process											owl:Class	
GO:0051247	biolink:NamedThing	positive regulation of protein metabolic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a protein.	tmpzr1t_l9r_go_relaxed.owl	activation of protein metabolic process|positive regulation of protein metabolism|up regulation of protein metabolic process|upregulation of protein metabolic process|up-regulation of protein metabolic process|stimulation of protein metabolic process													biological_process											owl:Class	
GO:1904278	biolink:NamedThing	positive regulation of wax biosynthetic process	Any process that activates or increases the frequency, rate or extent of wax biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	up regulation of wax synthesis|positive regulation of wax anabolism|upregulation of wax synthesis|upregulation of wax biosynthesis|upregulation of wax biosynthetic process|activation of wax biosynthetic process|up-regulation of wax biosynthesis|activation of wax biosynthesis|upregulation of wax formation|up-regulation of wax formation|up regulation of wax formation|positive regulation of wax biosynthesis|activation of wax anabolism|up-regulation of wax anabolism|up regulation of wax biosynthetic process|positive regulation of wax synthesis|activation of wax formation|up-regulation of wax biosynthetic process|up regulation of wax anabolism|upregulation of wax anabolism|activation of wax synthesis|positive regulation of wax formation|up-regulation of wax synthesis|up regulation of wax biosynthesis							tb	2015-06-03T17:20:19Z					biological_process											owl:Class	
GO:0009891	biolink:NamedThing	positive regulation of biosynthetic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of formation|positive regulation of biosynthesis|up-regulation of biosynthetic process|upregulation of biosynthetic process|stimulation of biosynthetic process|positive regulation of synthesis|up regulation of biosynthetic process|activation of biosynthetic process|positive regulation of anabolism													biological_process											owl:Class	
GO:0010781	biolink:NamedThing	meiotic DNA double-strand break formation involved in meiotic gene conversion	The cell cycle process in which double-strand breaks are generated at defined hotspots throughout the genome during meiosis I resulting in meiotic gene conversion. Meiotic gene conversion is the cell cycle process in which genetic information is transferred from one helix to another.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0042138	biolink:NamedThing	meiotic DNA double-strand break formation	The cell cycle process in which double-strand breaks are generated at defined hotspots throughout the genome during meiosis I. This results in the initiation of meiotic recombination.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0034356	biolink:NamedThing	NAD biosynthesis via nicotinamide riboside salvage pathway	The chemical reactions and pathways resulting in the formation of nicotinamide adenine dinucleotide (NAD) from the vitamin precursor nicotinamide riboside.	tmpzr1t_l9r_go_relaxed.owl	NR salvage pathway|nicotinamide riboside salvage pathway													biological_process											owl:Class	
GO:0009435	biolink:NamedThing	NAD biosynthetic process	The chemical reactions and pathways resulting in the formation of nicotinamide adenine dinucleotide, a coenzyme present in most living cells and derived from the B vitamin nicotinic acid; biosynthesis may be of either the oxidized form, NAD, or the reduced form, NADH.	tmpzr1t_l9r_go_relaxed.owl	oxidized nicotinamide adenine dinucleotide biosynthetic process|nicotinamide adenine dinucleotide biosynthesis|NAD biosynthesis|NAD (oxidized) biosynthesis|reduced NAD biosynthetic process|NAD anabolism|NAD (reduced) biosynthetic process|NADH biosynthetic process|NAD formation|reduced nicotinamide adenine dinucleotide biosynthetic process|NADH biosynthesis|NAD synthesis|reduced nicotinamide adenine dinucleotide biosynthesis|NAD (oxidized) biosynthetic process|nicotinamide adenine dinucleotide biosynthetic process|oxidized nicotinamide adenine dinucleotide biosynthesis|oxidized NAD biosynthesis|NAD (reduced) biosynthesis|oxidized NAD biosynthetic process|reduced NAD biosynthesis											GO:0006736		biological_process											owl:Class	
GO:0046385	biolink:NamedThing	deoxyribose phosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of deoxyribose phosphate, the phosphorylated sugar 2-deoxy-erythro-pentose.	tmpzr1t_l9r_go_relaxed.owl	deoxyribose phosphate anabolism|deoxyribose phosphate biosynthesis|deoxyribose phosphate synthesis|deoxyribose phosphate formation													biological_process											owl:Class	
GO:0019692	biolink:NamedThing	deoxyribose phosphate metabolic process	The chemical reactions and pathways involving deoxyribose phosphate, the phosphorylated sugar 2-deoxy-erythro-pentose.	tmpzr1t_l9r_go_relaxed.owl	deoxyribose phosphate metabolism													biological_process											owl:Class	
GO:0006021	biolink:NamedThing	inositol biosynthetic process	The chemical reactions and pathways resulting in the formation of inositol, 1,2,3,4,5,6-cyclohexanehexol, a growth factor for animals and microorganisms.	tmpzr1t_l9r_go_relaxed.owl	inositol biosynthesis|inositol formation|inositol anabolism|myo-inositol biosynthesis|myo-inositol biosynthetic process|vitamin Bh biosynthetic process|inositol synthesis|vitamin Bh biosynthesis													biological_process											owl:Class	
GO:0006020	biolink:NamedThing	inositol metabolic process	The chemical reactions and pathways involving inositol, 1,2,3,4,5,6-cyclohexanehexol, a growth factor for animals and microorganisms.	tmpzr1t_l9r_go_relaxed.owl	myo-inositol metabolism|vitamin Bh metabolic process|vitamin Bh metabolism|inositol metabolism|myo-inositol metabolic process				Wikipedia:Inositol									biological_process											owl:Class	
GO:0019639	biolink:NamedThing	6-hydroxycineole catabolic process	The chemical reactions and pathways resulting in the breakdown of 6-hydroxycineole (6-hydroxy-1,8-epoxy-p-menthane), a hydrocarbon with the formula C10H18O2.	tmpzr1t_l9r_go_relaxed.owl	6-endo-hydroxycineole catabolic process|6-endo-hydroxycineole catabolism|hydroxycineol catabolism|6-hydroxycineole degradation|6-hydroxycineole catabolism|6-hydroxycineole breakdown|hydroxycineol catabolic process				MetaCyc:6-HYDROXYCINEOLE-DEGRADATION-PWY									biological_process											owl:Class	
GO:1901502	biolink:NamedThing	ether catabolic process	The chemical reactions and pathways resulting in the breakdown of ether.	tmpzr1t_l9r_go_relaxed.owl	ether catabolism|ether degradation|ether breakdown							pr	2012-10-17T09:42:43Z					biological_process											owl:Class	
GO:2001214	biolink:NamedThing	positive regulation of vasculogenesis	Any process that activates or increases the frequency, rate or extent of vasculogenesis.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of vascular morphogenesis							yaf	2011-11-15T01:22:39Z					biological_process											owl:Class	
GO:2001212	biolink:NamedThing	regulation of vasculogenesis	Any process that modulates the frequency, rate or extent of vasculogenesis.	tmpzr1t_l9r_go_relaxed.owl	regulation of vascular morphogenesis							yaf	2011-11-15T01:22:31Z					biological_process											owl:Class	
GO:0018981	biolink:NamedThing	triethanolamine metabolic process	The chemical reactions and pathways involving triethanolamine, a combustible, hygroscopic, colorless liquid commonly used in dry-cleaning solutions, cosmetics, detergents, textile processing, wool scouring, and as a corrosion inhibitor and pharmaceutical alkalizing agent.	tmpzr1t_l9r_go_relaxed.owl	triethanolamine metabolism				UM-BBD_pathwayID:tea									biological_process											owl:Class	
GO:0044107	biolink:NamedThing	cellular alcohol metabolic process	The chemical reactions and pathways involving alcohols, any of a class of compounds containing one or more hydroxyl groups attached to a saturated carbon atom, as carried out by individual cells.	tmpzr1t_l9r_go_relaxed.owl								jl	2009-07-15T01:36:19Z					biological_process											owl:Class	
GO:1900958	biolink:NamedThing	positive regulation of 17-methylnonadec-1-ene biosynthetic process	Any process that activates or increases the frequency, rate or extent of 17-methylnonadec-1-ene biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of 17-methylnonadec-1-ene anabolism|up-regulation of 17-methylnonadec-1-ene formation|positive regulation of 17-methylnonadec-1-ene biosynthesis|up-regulation of 17-methylnonadec-1-ene synthesis|up-regulation of 17-methylnonadec-1-ene biosynthesis|activation of 17-methylnonadec-1-ene biosynthesis|up regulation of 17-methylnonadec-1-ene synthesis|upregulation of 17-methylnonadec-1-ene formation|up regulation of 17-methylnonadec-1-ene anabolism|activation of 17-methylnonadec-1-ene formation|upregulation of 17-methylnonadec-1-ene synthesis|up regulation of 17-methylnonadec-1-ene biosynthetic process|up-regulation of 17-methylnonadec-1-ene biosynthetic process|activation of 17-methylnonadec-1-ene anabolism|positive regulation of 17-methylnonadec-1-ene anabolism|positive regulation of 17-methylnonadec-1-ene formation|upregulation of 17-methylnonadec-1-ene anabolism|positive regulation of 17-methylnonadec-1-ene synthesis|activation of 17-methylnonadec-1-ene synthesis|up regulation of 17-methylnonadec-1-ene formation|activation of 17-methylnonadec-1-ene biosynthetic process|upregulation of 17-methylnonadec-1-ene biosynthetic process|up regulation of 17-methylnonadec-1-ene biosynthesis|upregulation of 17-methylnonadec-1-ene biosynthesis							tt	2012-06-14T03:27:46Z					biological_process											owl:Class	
GO:1900956	biolink:NamedThing	regulation of 17-methylnonadec-1-ene biosynthetic process	Any process that modulates the frequency, rate or extent of 17-methylnonadec-1-ene biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of 17-methylnonadec-1-ene formation|regulation of 17-methylnonadec-1-ene anabolism|regulation of 17-methylnonadec-1-ene synthesis|regulation of 17-methylnonadec-1-ene biosynthesis							tt	2012-06-14T03:27:18Z					biological_process											owl:Class	
GO:0003322	biolink:NamedThing	pancreatic A cell development	The process whose specific outcome is the progression of a pancreatic A cell over time, from its formation to the mature structure. A pancreatic A cell is a cell in the pancreas that secretes glucagon.	tmpzr1t_l9r_go_relaxed.owl	pancreatic alpha cell development							dph	2009-11-02T08:13:55Z					biological_process											owl:Class	
GO:0010334	biolink:NamedThing	sesquiterpene synthase activity	Catalysis of the reaction: trans,trans-farnesyl diphosphate = a sesquiterpene + diphosphate. Sesquiterpenes are terpenes containing three isoprene units, i.e. 15 carbons.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0010333	biolink:NamedThing	terpene synthase activity	Catalysis of the formation of cyclic terpenes through the cyclization of linear terpenes (e.g. isopentenyl-PP, geranyl-PP, farnesyl-PP and geranylgeranyl-PP) containing varying numbers of isoprene units.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1900019	biolink:NamedThing	regulation of protein kinase C activity	Any process that modulates the frequency, rate or extent of protein kinase C activity.	tmpzr1t_l9r_go_relaxed.owl	regulation of PKC activity|regulation of PKC							bf	2012-01-11T03:50:47Z					biological_process											owl:Class	
GO:0046493	biolink:NamedThing	lipid A metabolic process	The chemical reactions and pathways involving lipid A, the glycolipid group of bacterial lipopolysaccharides, consisting of four to six fatty acyl chains linked to two glucosamine residues. Further modifications of the backbone are common.	tmpzr1t_l9r_go_relaxed.owl	lipid A metabolism													biological_process											owl:Class	
GO:1901269	biolink:NamedThing	lipooligosaccharide metabolic process	The chemical reactions and pathways involving lipooligosaccharide.	tmpzr1t_l9r_go_relaxed.owl	lipooligosaccharide metabolism							yaf	2012-08-17T14:31:26Z					biological_process											owl:Class	
GO:0001842	biolink:NamedThing	neural fold formation	The process in which the neural fold is formed. The edges of the neural plate thicken and move up to form a U-shaped structure called the neural groove.	tmpzr1t_l9r_go_relaxed.owl	neural groove formation													biological_process											owl:Class	
GO:0060571	biolink:NamedThing	morphogenesis of an epithelial fold	The morphogenetic process in which an epithelial sheet bends along a linear axis.	tmpzr1t_l9r_go_relaxed.owl	folding of an epithelial sheet|epithelial folding							dph	2009-04-30T09:27:17Z					biological_process											owl:Class	
GO:0006421	biolink:NamedThing	asparaginyl-tRNA aminoacylation	The process of coupling asparagine to asparaginyl-tRNA, catalyzed by asparaginyl-tRNA synthetase. The asparaginyl-tRNA synthetase is a  class-II synthetase. The activated amino acid is transferred to the 3'-OH group of an asparagine-accetping tRNA.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0006418	biolink:NamedThing	tRNA aminoacylation for protein translation	The synthesis of aminoacyl tRNA by the formation of an ester bond between the 3'-hydroxyl group of the most 3' adenosine of the tRNA and the alpha carboxylic acid  group of an amino acid, to be used in ribosome-mediated polypeptide synthesis.	tmpzr1t_l9r_go_relaxed.owl	tRNA charging				MetaCyc:TRNA-CHARGING-PWY									biological_process											owl:Class	
GO:1901463	biolink:NamedThing	regulation of tetrapyrrole biosynthetic process	Any process that modulates the frequency, rate or extent of tetrapyrrole biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of tetrapyrrole anabolism|regulation of tetrapyrrole biosynthesis|regulation of tetrapyrrole formation|regulation of tetrapyrrole synthesis							tt	2012-10-02T14:34:14Z					biological_process											owl:Class	
GO:1902723	biolink:NamedThing	negative regulation of skeletal muscle satellite cell proliferation	Any process that stops, prevents or reduces the frequency, rate or extent of satellite cell proliferation.	tmpzr1t_l9r_go_relaxed.owl	inhibition of satellite cell proliferation|downregulation of satellite cell proliferation|down regulation of satellite cell proliferation|down-regulation of satellite cell proliferation							mr	2014-02-24T16:09:46Z					biological_process											owl:Class	
GO:0014859	biolink:NamedThing	negative regulation of skeletal muscle cell proliferation	Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle cell proliferation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0140491	biolink:NamedThing	ubiquitin-like hydrolase activity	An activity that cleaves ubiquitin or ubiquitin-like proteins (ULP) from target proteins.	tmpzr1t_l9r_go_relaxed.owl	ubiquitinyl-like hydrolase activity	https://github.com/geneontology/go-ontology/issues/17398						pg	2020-07-01T12:37:19Z					molecular_function											owl:Class	
GO:0008233	biolink:NamedThing	peptidase activity	Catalysis of the hydrolysis of a peptide bond. A peptide bond is a covalent bond formed when the carbon atom from the carboxyl group of one amino acid shares electrons with the nitrogen atom from the amino group of a second amino acid.	tmpzr1t_l9r_go_relaxed.owl	peptide hydrolase activity|hydrolase, acting on peptide bonds|protease activity|peptidase activity, acting on L-amino acid peptides|peptidase activity, acting on D-amino acid peptides|proteinase activity				Reactome:R-HSA-3000243|Reactome:R-HSA-205112|Reactome:R-HSA-6803060|Reactome:R-HSA-5693319|Reactome:R-HSA-376149|Reactome:R-HSA-5684864|Reactome:R-HSA-448678|Reactome:R-HSA-3065959|EC:3.4.-.-|Reactome:R-HSA-3065958|Reactome:R-HSA-5655483|Reactome:R-HSA-5685902|Reactome:R-HSA-4167501|Reactome:R-HSA-3139027							GO:0070011|GO:0070010		molecular_function											owl:Class	
GO:0042573	biolink:NamedThing	retinoic acid metabolic process	The chemical reactions and pathways involving retinoic acid, one of the three components that makes up vitamin A.	tmpzr1t_l9r_go_relaxed.owl	vitamin A1 acid metabolic process|retinoic acid metabolism|vitamin A1 acid metabolism													biological_process											owl:Class	
GO:0032787	biolink:NamedThing	monocarboxylic acid metabolic process	The chemical reactions and pathways involving monocarboxylic acids, any organic acid containing one carboxyl (COOH) group or anion (COO-).	tmpzr1t_l9r_go_relaxed.owl	monocarboxylate metabolic process|monocarboxylic acid metabolism													biological_process											owl:Class	
GO:0015413	biolink:NamedThing	ABC-type nickel transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Ni2+(out) = ADP + phosphate + Ni2+(in).	tmpzr1t_l9r_go_relaxed.owl	ATPase-coupled nickel transmembrane transporter activity|nickel porter activity|nickel transporting ATPase activity|ATP-dependent nickel transmembrane transporter activity|nickel ABC transporter activity|nickel-transporting ATPase activity|nickel ABC transporter				MetaCyc:3.6.3.24-RXN|MetaCyc:ABC-20-RXN|RHEA:15557|EC:7.2.2.11							GO:0102016		molecular_function											owl:Class	
GO:0015099	biolink:NamedThing	nickel cation transmembrane transporter activity	Enables the transfer of nickel (Ni) cations from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	zinc, cadmium, cobalt, nickel, lead-efflux ATPase activity				RHEA:29831									molecular_function											owl:Class	
GO:0051903	biolink:NamedThing	S-(hydroxymethyl)glutathione dehydrogenase activity	Catalysis of the reaction: S-(hydroxymethyl)glutathione + NAD(P)+ = S-formylglutathione + NAD(P)H + H+.	tmpzr1t_l9r_go_relaxed.owl	NAD-dependent formaldehyde dehydrogenase activity|glutathione-dependent formaldehyde dehydrogenase activity|GD-FALDH activity|FDH activity|S-(hydroxymethyl)glutathione:NAD+ oxidoreductase activity|chi-ADH activity|NAD-linked formaldehyde dehydrogenase activity|ADH3 activity|NAD- and glutathione-dependent formaldehyde dehydrogenase activity|class III alcohol dehydrogenase activity|GS-FDH activity|formic dehydrogenase activity				MetaCyc:RXN-2962|KEGG_REACTION:R07140|Reactome:R-HSA-5692237|KEGG_REACTION:R06983|EC:1.1.1.284|UM-BBD_reactionID:r1146									molecular_function											owl:Class	
GO:0046598	biolink:NamedThing	positive regulation of viral entry into host cell	Any process that activates or increases the frequency, rate or extent of the introduction of viral entry into the host cell.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of viral penetration into host cell													biological_process											owl:Class	
GO:1903902	biolink:NamedThing	positive regulation of viral life cycle	Any process that activates or increases the frequency, rate or extent of viral life cycle.	tmpzr1t_l9r_go_relaxed.owl	activation of viral life cycle|up-regulation of viral replication|activation of lytic viral life cycle|up-regulation of lytic viral life cycle|up regulation of viral replication|upregulation of viral life cycle|up-regulation of viral infectious cycle|upregulation of viral assembly, maturation, egress, and release|up regulation of viral assembly, maturation, egress, and release|activation of viral assembly, maturation, egress, and release|positive regulation of viral assembly, maturation, egress, and release|up regulation of viral infectious cycle|upregulation of lytic viral life cycle|positive regulation of lytic viral life cycle|up regulation of viral life cycle|upregulation of viral infectious cycle|activation of viral infectious cycle|positive regulation of viral replication|activation of viral replication|up-regulation of viral life cycle|up regulation of lytic viral life cycle|positive regulation of viral infectious cycle|upregulation of viral replication|up-regulation of viral assembly, maturation, egress, and release							pga	2015-02-09T10:22:25Z					biological_process											owl:Class	
GO:0030566	biolink:NamedThing	snRNA modification guide activity	Specifies the site of a posttranscriptional modification in an snRNA molecule by base pairing with a short sequence around the target residue.	tmpzr1t_l9r_go_relaxed.owl						Note that this term describes the activity of a nucleic acid, usually RNA, gene product that interacts with other RNA molecules via base pairing; it should not be used to annotate proteins.								molecular_function											owl:Class	
GO:0017069	biolink:NamedThing	snRNA binding	Binding to a small nuclear RNA (snRNA).	tmpzr1t_l9r_go_relaxed.owl	small nuclear RNA binding|base pairing with snRNA											GO:0000945		molecular_function											owl:Class	
GO:0006566	biolink:NamedThing	threonine metabolic process	The chemical reactions and pathways involving threonine (2-amino-3-hydroxybutyric acid), a polar, uncharged, essential amino acid found in peptide linkage in proteins.	tmpzr1t_l9r_go_relaxed.owl	methionine and threonine metabolic process|methionine and threonine metabolism|threonine metabolism				UM-BBD_pathwayID:met									biological_process											owl:Class	
GO:1990124	biolink:NamedThing	messenger ribonucleoprotein complex	A ribonucleoprotein complex containing both protein and messenger RNA (mRNA) molecules.	tmpzr1t_l9r_go_relaxed.owl	messenger ribonucleoprotein particle|mRNA-protein complex|mRNP|mRNP complex							bf	2013-06-13T09:20:52Z					cellular_component											owl:Class	
GO:0043656	biolink:NamedThing	host intracellular region	That space within the plasma membrane of a host cell.	tmpzr1t_l9r_go_relaxed.owl	intracellular region of host|host intracellular													cellular_component											owl:Class	
GO:0033643	biolink:NamedThing	host cell part	Any constituent part of a host cell. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl						Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.								cellular_component											owl:Class	
GO:1901956	biolink:NamedThing	positive regulation of retrograde dense core granule transport	Any process that activates or increases the frequency, rate or extent of retrograde dense core granule transport.	tmpzr1t_l9r_go_relaxed.owl	upregulation of retrograde dense core granule transport|activation of retrograde dense core granule transport|up-regulation of retrograde dense core granule transport|up regulation of retrograde dense core granule transport							pr	2013-02-19T13:36:52Z					biological_process											owl:Class	
GO:0060713	biolink:NamedThing	labyrinthine layer morphogenesis	The process in which the labyrinthine layer of the placenta is generated and organized.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-06-10T08:10:19Z					biological_process											owl:Class	
GO:0048598	biolink:NamedThing	embryonic morphogenesis	The process in which anatomical structures are generated and organized during the embryonic phase. The embryonic phase begins with zygote formation. The end of the embryonic phase is organism-specific. For example, it would be at birth for mammals, larval hatching for insects and seed dormancy in plants.	tmpzr1t_l9r_go_relaxed.owl	embryonic anatomical structure morphogenesis											GO:0048828		biological_process											owl:Class	
GO:0030649	biolink:NamedThing	aminoglycoside antibiotic catabolic process	The chemical reactions and pathways resulting in the breakdown of an aminoglycoside antibiotic, any member of a group of broad spectrum antibiotics, of similar toxicity and pharmacology, that contain an aminodeoxysugar, an amino- or guanidino-substituted inositol ring, and one or more residues of other sugars. The group includes streptomycin, neomycin, framycetin, kanamycin, paromomycin, and gentamicin.	tmpzr1t_l9r_go_relaxed.owl	aminoglycoside antibiotic breakdown|aminoglycoside antibiotic degradation|aminoglycoside antibiotic catabolism													biological_process											owl:Class	
GO:0030647	biolink:NamedThing	aminoglycoside antibiotic metabolic process	The chemical reactions and pathways involving an aminoglycoside antibiotic, any member of a group of broad spectrum antibiotics, of similar toxicity and pharmacology, that contain an aminodeoxysugar, an amino- or guanidino-substituted inositol ring, and one or more residues of other sugars. The group includes streptomycin, neomycin, framycetin, kanamycin, paromomycin, and gentamicin.	tmpzr1t_l9r_go_relaxed.owl	aminoglycoside antibiotic metabolism													biological_process											owl:Class	
GO:0003340	biolink:NamedThing	negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis	Any process that decreases the rate, frequency or extent of the transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the metanephros.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-11-24T09:46:12Z					biological_process											owl:Class	
GO:0003339	biolink:NamedThing	regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis	Any process that modulates the rate, frequency or extent of the transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the metanephros.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-11-24T09:43:04Z					biological_process											owl:Class	
GO:0103102	biolink:NamedThing	UDP-glucose:8-methylthiooctylhydroximate S-glucosyltransferase activity	Catalysis of the reaction: UDP-alpha-D-glucose + 8-methylthiooctylhydroximate <=> H+ + 7-methylthioheptyldesulfoglucosinolate + UDP.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXNQT-4327|EC:2.4.1.195									molecular_function											owl:Class	
GO:0046249	biolink:NamedThing	alpha-pinene catabolic process	The chemical reactions and pathways resulting in the breakdown of alpha-pinene, a monoterpene that may be a significant factor affecting bacterial activities in nature.	tmpzr1t_l9r_go_relaxed.owl	alpha-pinene degradation|alpha-pinene catabolism|alpha-pinene breakdown													biological_process											owl:Class	
GO:0033074	biolink:NamedThing	pinene catabolic process	The chemical reactions and pathways leading to the breakdown of the monoterpenoid pinene; alpha-pinene is (1S,5S)-2,6,6-trimethylbicyclo[3.1.1]hept-2-ene, and beta-pinene is (1S,5S)-6,6-dimethyl-2-methylenebicyclo[3.1.1]heptane.	tmpzr1t_l9r_go_relaxed.owl	pinene catabolism|pinene breakdown|pinene degradation													biological_process											owl:Class	
GO:0035176	biolink:NamedThing	social behavior	Behavior directed towards society, or taking place between members of the same species. Occurs predominantly, or only, in individuals that are part of a group.	tmpzr1t_l9r_go_relaxed.owl	social behaviour|cooperative behavior				Wikipedia:Social_behavior	Behavior such as predation which involves members of different species is not social. Communication between members of different species is also not social behavior.								biological_process											owl:Class	
GO:0007610	biolink:NamedThing	behavior	The internally coordinated responses (actions or inactions) of animals (individuals or groups) to internal or external stimuli, via a mechanism that involves nervous system activity.	tmpzr1t_l9r_go_relaxed.owl	behavioural response to stimulus|single-organism behavior|behaviour|behavioral response to stimulus				Wikipedia:Behavior	1. Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation reviews. 2. While a broader definition of behavior encompassing plants and single cell organisms would be justified on the basis of some usage (see PMID:20160973 for discussion), GO uses a tight definition that limits behavior to animals and to responses involving the nervous system, excluding plant responses that GO classifies under development, and responses of unicellular organisms that has general classifications for covering the responses of cells in multicellular organisms (e.g. cell chemotaxis).		jl	2012-09-20T14:06:08Z			GO:0023032|GO:0044708|GO:0044709		biological_process											owl:Class	
GO:0042480	biolink:NamedThing	negative regulation of eye photoreceptor cell development	Any process that stops, prevents, or reduces the frequency, rate or extent of eye photoreceptor development.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of eye photoreceptor cell development|downregulation of eye photoreceptor cell development|down regulation of eye photoreceptor cell development|negative regulation of eye photoreceptor development|inhibition of eye photoreceptor cell development													biological_process											owl:Class	
GO:0021770	biolink:NamedThing	parahippocampal gyrus development	The progression of the parahippocampal gyrus over time from its initial formation until its mature state. The parahippocampal gyrus is a ridge in the cerebral cortex.	tmpzr1t_l9r_go_relaxed.owl	hippocampal gyrus development				Wikipedia:parahippocampal_gyrus									biological_process											owl:Class	
GO:0048856	biolink:NamedThing	anatomical structure development	The biological process whose specific outcome is the progression of an anatomical structure from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome.	tmpzr1t_l9r_go_relaxed.owl	development of an anatomical structure													biological_process											owl:Class	
GO:0120086	biolink:NamedThing	(3S)-(+)-asterisca-2(9),6-diene synthase activity	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = diphosphate + (3S)-(+)-asterisca-2(9),6-diene.	tmpzr1t_l9r_go_relaxed.owl	asterisca-2(9),6-diene synthase activity							krc	2017-08-02T14:55:38Z					molecular_function											owl:Class	
GO:0051947	biolink:NamedThing	regulation of gamma-aminobutyric acid uptake involved in transmission of nerve impulse	Any process that modulates the frequency, rate or extent of the directed movement of gamma-aminobutyric acid (GABA, 4-aminobutyrate) into a neuron or glial cell.	tmpzr1t_l9r_go_relaxed.owl	regulation of gamma-aminobutyric acid uptake during transmission of nerve impulse|regulation of 4-aminobutyrate reuptake|regulation of gamma-aminobutyric acid uptake involved in conduction of nerve impulse|regulation of GABA uptake during transmission of nerve impulse|regulation of GABA reuptake|regulation of 4-aminobutyrate uptake during transmission of nerve impulse|regulation of gamma-aminobutyric acid reuptake													biological_process											owl:Class	
GO:0033690	biolink:NamedThing	positive regulation of osteoblast proliferation	Any process that activates or increases the rate or extent of osteoblast proliferation.	tmpzr1t_l9r_go_relaxed.owl	up regulation of osteoblast proliferation|stimulation of osteoblast proliferation|up-regulation of osteoblast proliferation|upregulation of osteoblast proliferation|activation of osteoblast proliferation													biological_process											owl:Class	
GO:1904398	biolink:NamedThing	positive regulation of neuromuscular junction development	Any process that activates or increases the frequency, rate or extent of neuromuscular junction development.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of neuromuscular junction stability|up regulation of neuromuscular junction stability|up-regulation of neuromuscular junction development|up regulation of neuromuscular junction development|upregulation of neuromuscular junction organization|activation of neuromuscular junction organization|activation of neuromuscular junction stability|positive regulation of neuromuscular junction stability|upregulation of neuromuscular junction stability|up-regulation of NMJ stability|activation of neuromuscular junction development|up-regulation of neuromuscular junction organization|upregulation of NMJ stability|upregulation of neuromuscular junction development|activation of NMJ stability|positive regulation of NMJ stability|up regulation of NMJ stability|positive regulation of neuromuscular junction organization|up regulation of neuromuscular junction organization							sl	2015-06-23T19:23:54Z					biological_process											owl:Class	
GO:1904396	biolink:NamedThing	regulation of neuromuscular junction development	Any process that modulates the frequency, rate or extent of neuromuscular junction development.	tmpzr1t_l9r_go_relaxed.owl	regulation of neuromuscular junction organization|regulation of neuromuscular junction stability|regulation of NMJ stability							sl	2015-06-23T19:23:42Z					biological_process											owl:Class	
GO:0070507	biolink:NamedThing	regulation of microtubule cytoskeleton organization	Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins.	tmpzr1t_l9r_go_relaxed.owl	regulation of microtubule cytoskeleton organisation|regulation of microtubule dynamics													biological_process											owl:Class	
GO:0032886	biolink:NamedThing	regulation of microtubule-based process	Any process that modulates the frequency, rate or extent of any cellular process that depends upon or alters the microtubule cytoskeleton.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0046643	biolink:NamedThing	regulation of gamma-delta T cell activation	Any process that modulates the frequency, rate or extent of gamma-delta T cell activation.	tmpzr1t_l9r_go_relaxed.owl	regulation of gamma-delta T-cell activation|regulation of gamma-delta T lymphocyte activation|regulation of gamma-delta T-lymphocyte activation													biological_process											owl:Class	
GO:0004331	biolink:NamedThing	fructose-2,6-bisphosphate 2-phosphatase activity	Catalysis of the reaction: D-fructose 2,6-bisphosphate + H2O = D-fructose-6-phosphate + phosphate.	tmpzr1t_l9r_go_relaxed.owl	D-fructose-2,6-bisphosphate 2-phosphohydrolase activity|fructose-2,6-bisphosphatase activity|beta-D-fructose-2,6-bisphosphate 2-phosphohydrolase activity				Reactome:R-HSA-5628905|MetaCyc:3.1.3.46-RXN|EC:3.1.3.46|Reactome:R-HSA-70262|RHEA:17289							GO:0004330		molecular_function											owl:Class	
GO:0050308	biolink:NamedThing	sugar-phosphatase activity	Catalysis of the reaction: sugar phosphate + H2O = sugar + phosphate.	tmpzr1t_l9r_go_relaxed.owl	sugar-phosphate phosphatase activity|sugar-phosphate phosphohydrolase activity				EC:3.1.3.23|MetaCyc:SUGAR-PHOSPHATASE-RXN|KEGG_REACTION:R00804									molecular_function											owl:Class	
GO:0048239	biolink:NamedThing	negative regulation of DNA recombination at telomere	Any process that stops, prevents, or reduces the frequency, rate or extent of genetic recombination within the telomere.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of telomeric recombination at telomere|downregulation of telomeric recombination at telomere|down-regulation of telomeric recombination at telomere|suppression of telomeric recombination at telomere|down regulation of telomeric recombination at telomere|inhibition of telomeric recombination at telomere													biological_process											owl:Class	
GO:0045910	biolink:NamedThing	negative regulation of DNA recombination	Any process that stops, prevents, or reduces the frequency, rate or extent of DNA recombination.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of DNA recombination|down regulation of DNA recombination|downregulation of DNA recombination|inhibition of DNA recombination													biological_process											owl:Class	
GO:0009699	biolink:NamedThing	phenylpropanoid biosynthetic process	The chemical reactions and pathways resulting in the formation of aromatic derivatives of trans-cinnamic acid.	tmpzr1t_l9r_go_relaxed.owl	phenylpropanoid biosynthesis|phenylpropanoid formation|phenylpropanoid anabolism|phenylpropanoid synthesis													biological_process											owl:Class	
GO:0007165	biolink:NamedThing	signal transduction	The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.	tmpzr1t_l9r_go_relaxed.owl	signaling cascade|signalling cascade|signal transduction by trans-phosphorylation|signaling pathway|signal transduction by cis-phosphorylation|signal transduction by protein phosphorylation|signal transduction by conformational transition|signalling pathway				Wikipedia:Signal_transduction	Note that signal transduction is defined broadly to include a ligand interacting with a receptor, downstream signaling steps and a response being triggered. A change in form of the signal in every step is not necessary. Note that in many cases the end of this process is regulation of the initiation of transcription. Note that specific transcription factors may be annotated to this term, but core/general transcription machinery such as RNA polymerase should not.						GO:0023015|GO:0023014|GO:0023045|GO:0023016|GO:0023033		biological_process											owl:Class	
GO:0050794	biolink:NamedThing	regulation of cellular process	Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.	tmpzr1t_l9r_go_relaxed.owl	regulation of cellular physiological process											GO:0051244		biological_process											owl:Class	
GO:1903678	biolink:NamedThing	negative regulation of cap-independent translational initiation	Any process that stops, prevents or reduces the frequency, rate or extent of cap-independent translational initiation.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of cap-independent translational initiation|downregulation of cap-independent translational initiation|inhibition of cap-independent translational initiation|down regulation of cap-independent translational initiation							bf	2014-11-27T19:52:28Z					biological_process											owl:Class	
GO:1903677	biolink:NamedThing	regulation of cap-independent translational initiation	Any process that modulates the frequency, rate or extent of cap-independent translational initiation.	tmpzr1t_l9r_go_relaxed.owl								bf	2014-11-27T19:52:20Z					biological_process											owl:Class	
GO:1904522	biolink:NamedThing	positive regulation of myofibroblast cell apoptotic process	Any process that activates or increases the frequency, rate or extent of myofibroblast cell apoptotic process.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of MFB apoptosis|positive regulation of myofibroblast cell apoptosis|positive regulation of MFB apoptosis|up regulation of MFB apoptotic process|activation of MFB apoptotic process|positive regulation of MFB apoptotic process|up-regulation of myofibroblast cell apoptotic process|up-regulation of MFB apoptotic process|upregulation of myofibroblast cell apoptotic process|up regulation of myofibroblast cell apoptosis|upregulation of MFB apoptosis|upregulation of myofibroblast cell apoptosis|activation of MFB apoptosis|activation of myofibroblast cell apoptosis|activation of myofibroblast cell apoptotic process|up-regulation of myofibroblast cell apoptosis|upregulation of MFB apoptotic process|up regulation of myofibroblast cell apoptotic process|up regulation of MFB apoptosis							sl	2015-07-29T15:52:26Z					biological_process											owl:Class	
GO:0003431	biolink:NamedThing	growth plate cartilage chondrocyte development	The progression of a growth plate cartilage chondrocyte over time from after its fate commitment to the mature cell.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-12-22T12:32:49Z					biological_process											owl:Class	
GO:0003433	biolink:NamedThing	chondrocyte development involved in endochondral bone morphogenesis	The progression of a chondrocyte over time from after its commitment to its mature state where the chondrocyte will contribute to the shaping of an endochondral bone.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-12-22T12:42:44Z					biological_process											owl:Class	
GO:0043128	biolink:NamedThing	positive regulation of 1-phosphatidylinositol 4-kinase activity	Any process that activates or increases the activity of 1-phosphatidylinositol 4-kinase.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of 1-phosphatidylinositol 4-kinase activity|stimulation of 1-phosphatidylinositol 4-kinase activity|activation of 1-phosphatidylinositol 4-kinase activity|up regulation of 1-phosphatidylinositol 4-kinase activity|positive regulation of PI4K activity|upregulation of 1-phosphatidylinositol 4-kinase activity													biological_process											owl:Class	
GO:0090218	biolink:NamedThing	positive regulation of lipid kinase activity	Any process that increases the frequency, rate or extent of lipid kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a simple or complex lipid.	tmpzr1t_l9r_go_relaxed.owl								tb	2010-01-12T10:18:30Z					biological_process											owl:Class	
GO:1901599	biolink:NamedThing	(-)-pinoresinol biosynthetic process	The chemical reactions and pathways resulting in the formation of (-)-pinoresinol.	tmpzr1t_l9r_go_relaxed.owl	(-)-pinoresinol formation|(-)-pinoresinol anabolism|(-)-pinoresinol biosynthesis|(-)-pinoresinol synthesis							tb	2012-11-08T01:16:05Z					biological_process											owl:Class	
GO:0046189	biolink:NamedThing	phenol-containing compound biosynthetic process	The chemical reactions and pathways resulting in the formation of a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring.	tmpzr1t_l9r_go_relaxed.owl	phenol-containing compound synthesis|phenol-containing compound formation|phenol-containing compound anabolism|phenol-containing compound biosynthesis													biological_process											owl:Class	
GO:1900997	biolink:NamedThing	benzene biosynthetic process	The chemical reactions and pathways resulting in the formation of benzene.	tmpzr1t_l9r_go_relaxed.owl	benzene synthesis|benzene formation|benzene biosynthesis|benzene anabolism							yaf	2012-06-14T02:54:01Z					biological_process											owl:Class	
GO:1903851	biolink:NamedThing	negative regulation of cristae formation	Any process that stops, prevents or reduces the frequency, rate or extent of cristae formation.	tmpzr1t_l9r_go_relaxed.owl	down regulation of cristae formation|down-regulation of cristae formation|inhibition of cristae formation|downregulation of cristae formation					AN example of this is PINK1 in human (Q9BXM7) in PMID:19279012 inferred from mutant phenotype		pad	2015-01-27T09:42:33Z					biological_process											owl:Class	
GO:1903850	biolink:NamedThing	regulation of cristae formation	Any process that modulates the frequency, rate or extent of cristae formation.	tmpzr1t_l9r_go_relaxed.owl						AN example of this is PINK1 in human (Q9BXM7) in PMID:19279012 inferred from mutant phenotype		pad	2015-01-27T09:42:23Z					biological_process											owl:Class	
GO:1901983	biolink:NamedThing	regulation of protein acetylation	Any process that modulates the frequency, rate or extent of protein acetylation.	tmpzr1t_l9r_go_relaxed.owl	regulation of protein amino acid acetylation							ss	2013-03-14T00:40:07Z					biological_process											owl:Class	
GO:0031399	biolink:NamedThing	regulation of protein modification process	Any process that modulates the frequency, rate or extent of the covalent alteration of one or more amino acid residues within a protein.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0032567	biolink:NamedThing	dGTP binding	Binding to dGTP, deoxyguanosine triphosphate.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0032560	biolink:NamedThing	guanyl deoxyribonucleotide binding	Binding to a guanyl deoxyribonucleotide, any compound consisting of guanosine esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the deoxyribose moiety.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0044758	biolink:NamedThing	modulation by symbiont of host synaptic transmission	Any process in which a symbiont organism modulates the frequency, rate or extent of synaptic transmission, communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse, in its host organism.	tmpzr1t_l9r_go_relaxed.owl	regulation by symbiont of host synaptic transmission							jl	2012-12-06T15:34:05Z					biological_process											owl:Class	
GO:0044068	biolink:NamedThing	modulation by symbiont of host cellular process	Any process in which a symbiont organism modulates the frequency, rate or extent of a cellular process, any process that is carried out at the cellular level, but not necessarily restricted to a single cell, in its host organism.	tmpzr1t_l9r_go_relaxed.owl	modulation of host cellular process by symbiont|regulation of host cellular process by symbiont|regulation by symbiont of host cellular process													biological_process											owl:Class	
GO:0035579	biolink:NamedThing	specific granule membrane	The lipid bilayer surrounding a specific granule, a granule with a membranous, tubular internal structure, found primarily in mature neutrophil cells. Most are released into the extracellular fluid. Specific granules contain lactoferrin, lysozyme, vitamin B12 binding protein and elastase.	tmpzr1t_l9r_go_relaxed.owl	secondary granule membrane							bf	2010-10-05T01:32:47Z					cellular_component											owl:Class	
GO:0030667	biolink:NamedThing	secretory granule membrane	The lipid bilayer surrounding a secretory granule.	tmpzr1t_l9r_go_relaxed.owl	secretory vesicle membrane													cellular_component											owl:Class	
GO:1903852	biolink:NamedThing	positive regulation of cristae formation	Any process that activates or increases the frequency, rate or extent of cristae formation.	tmpzr1t_l9r_go_relaxed.owl	up regulation of cristae formation|activation of cristae formation|up-regulation of cristae formation|upregulation of cristae formation					AN example of this is PINK1 in human (Q9BXM7) in PMID:19279012 inferred from mutant phenotype		pad	2015-01-27T09:42:42Z					biological_process											owl:Class	
GO:0010822	biolink:NamedThing	positive regulation of mitochondrion organization	Any process that increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a mitochondrion.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of mitochondrion organisation													biological_process											owl:Class	
GO:0032811	biolink:NamedThing	negative regulation of epinephrine secretion	Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of epinephrine.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of epinephrine secretion|negative regulation of adrenaline secretion|down regulation of epinephrine secretion|inhibition of epinephrine secretion|downregulation of epinephrine secretion													biological_process											owl:Class	
GO:0033604	biolink:NamedThing	negative regulation of catecholamine secretion	Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a catecholamine.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of catecholamine secretion|downregulation of catecholamine secretion|down regulation of catecholamine secretion|inhibition of catecholamine secretion													biological_process											owl:Class	
GO:0102794	biolink:NamedThing	cinnamaldehyde:oxygen oxidoreductase activity	Catalysis of the reaction: cinnamaldehyde + O2 + H2O = H+ + trans-cinnamate + hydrogen peroxide.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-8089|EC:1.2.3.9									molecular_function											owl:Class	
GO:0016623	biolink:NamedThing	oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which an aldehyde or ketone (oxo) group acts as a hydrogen or electron donor and reduces oxygen.	tmpzr1t_l9r_go_relaxed.owl					EC:1.2.3.-									molecular_function											owl:Class	
GO:0101006	biolink:NamedThing	protein histidine phosphatase activity	Catalysis of the reaction: protein histidine phosphate + H2O = protein histidine + phosphate.	tmpzr1t_l9r_go_relaxed.owl	phosphohistidine phosphatase activity	https://github.com/geneontology/go-ontology/issues/21517			EC:3.9.1.3|RHEA:47964	This eukaryotic enzyme dephosphorylates phosphorylated histidine residues within proteins and peptides. The enzyme acts on phosphate groups attached to both the pros- (RHEA:47964) and tele- (RHEA:47960) nitrogen atoms, but the pros- position is somewhat preferred (by a factor of two at the most) (EC:3.9.1.3).						GO:0008969		molecular_function											owl:Class	
GO:0016825	biolink:NamedThing	hydrolase activity, acting on acid phosphorus-nitrogen bonds	Catalysis of the hydrolysis of any acid phosphorus-nitrogen bond.	tmpzr1t_l9r_go_relaxed.owl					EC:3.9.1.-									molecular_function											owl:Class	
GO:0030811	biolink:NamedThing	regulation of nucleotide catabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of nucleotides.	tmpzr1t_l9r_go_relaxed.owl	regulation of nucleotide catabolism|regulation of nucleotide breakdown|regulation of nucleotide degradation													biological_process											owl:Class	
GO:0034614	biolink:NamedThing	cellular response to reactive oxygen species	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reactive oxygen species stimulus. Reactive oxygen species include singlet oxygen, superoxide, and oxygen free radicals.	tmpzr1t_l9r_go_relaxed.owl	cellular response to AOS|cellular response to ROI|cellular response to reactive oxygen intermediate|cellular response to reactive oxidative species|cellular response to active oxygen species|cellular response to ROS													biological_process											owl:Class	
GO:0034599	biolink:NamedThing	cellular response to oxidative stress	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.	tmpzr1t_l9r_go_relaxed.owl	adaptive response to oxidative stress													biological_process											owl:Class	
GO:0018970	biolink:NamedThing	toluene metabolic process	The chemical reactions and pathways involving toluene, a volatile monoaromatic hydrocarbon found in crude petroleum and petroleum products such as gasoline and commonly used as a paint thinning agent and in other solvent applications.	tmpzr1t_l9r_go_relaxed.owl	methylbenzene metabolic process|toluene metabolism|methylbenzene metabolism													biological_process											owl:Class	
GO:0072490	biolink:NamedThing	toluene-containing compound metabolic process	The chemical reactions and pathways involving toluene, methylbenzene (formula C7H8), or any of its derivatives.	tmpzr1t_l9r_go_relaxed.owl	toluene-containing compound metabolism|toluene and derivative metabolic process							mah	2010-12-14T03:46:52Z					biological_process											owl:Class	
GO:0046471	biolink:NamedThing	phosphatidylglycerol metabolic process	The chemical reactions and pathways involving phosphatidylglycerols, any of a class of phospholipids in which the phosphatidyl group is esterified to the hydroxyl group of glycerol. They are important constituents of cell membranes.	tmpzr1t_l9r_go_relaxed.owl	phosphatidylglycerol metabolism													biological_process											owl:Class	
GO:0006650	biolink:NamedThing	glycerophospholipid metabolic process	The chemical reactions and pathways involving glycerophospholipids, any derivative of glycerophosphate that contains at least one O-acyl, O-alkyl, or O-alkenyl group attached to the glycerol residue.	tmpzr1t_l9r_go_relaxed.owl	glycerophospholipid metabolism|phosphoglyceride metabolic process|phosphoglyceride metabolism|alpha-glycerophosphate pathway											GO:0006652		biological_process											owl:Class	
GO:0002345	biolink:NamedThing	peripheral B cell receptor editing	The process that takes place mainly in germinal center B cells in which a large number of mutations are generated in the heavy chain and light chain V-region genes and their immediately surrounding introns in order to increase antibody diversity and contribute to affinity maturation.	tmpzr1t_l9r_go_relaxed.owl	peripheral B-cell receptor editing|peripheral B-lymphocyte receptor editing|peripheral B lymphocyte receptor editing													biological_process											owl:Class	
GO:0019686	biolink:NamedThing	purine nucleoside interconversion	The chemical reactions and pathways by which a purine nucleoside is synthesized from another purine nucleoside.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0015949	biolink:NamedThing	nucleobase-containing small molecule interconversion	The chemical reactions and pathways by which a nucleobase, nucleoside or nucleotide small molecule is synthesized from another nucleobase, nucleoside or nucleotide small molecule.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:P1-PWY									biological_process											owl:Class	
GO:0047478	biolink:NamedThing	aspartate-ammonia ligase (ADP-forming) activity	Catalysis of the reaction: L-aspartate + ATP + NH(4)(+) = L-asparagine + ADP + 2 H(+) + phosphate.	tmpzr1t_l9r_go_relaxed.owl	asparagine synthetase (ADP-forming) activity|asparagine synthetase (adenosine diphosphate-forming)|L-aspartate:ammonia ligase (ADP-forming)				EC:6.3.1.4|MetaCyc:6.3.1.4-RXN|RHEA:14197|KEGG_REACTION:R00482									molecular_function											owl:Class	
GO:0016880	biolink:NamedThing	acid-ammonia (or amide) ligase activity	Catalysis of the ligation of an acid to ammonia (NH3) or an amide via a carbon-nitrogen bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.	tmpzr1t_l9r_go_relaxed.owl	amide synthase activity				EC:6.3.1.-									molecular_function											owl:Class	
GO:0017190	biolink:NamedThing	N-terminal peptidyl-aspartic acid acetylation	The acetylation of the N-terminal aspartic acid of proteins; catalyzed by aspartate N-acetyltransferase.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0042	See also the molecular function term 'aspartate N-acetyltransferase activity ; GO:0017188'.								biological_process											owl:Class	
GO:0018197	biolink:NamedThing	peptidyl-aspartic acid modification	The modification of peptidyl-aspartic acid.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0051170	biolink:NamedThing	import into nucleus	The directed movement of substances into the nucleus.	tmpzr1t_l9r_go_relaxed.owl	single-organism nuclear import|nuclear import|substance nuclear import|single organism nuclear import							jl	2013-12-19T15:26:34Z			GO:1902593		biological_process											owl:Class	
GO:0006913	biolink:NamedThing	nucleocytoplasmic transport	The directed movement of molecules between the nucleus and the cytoplasm.	tmpzr1t_l9r_go_relaxed.owl	nucleocytoplasmic shuttling					Note that transport through the nuclear pore complex is not transmembrane because the nuclear membrane is a double membrane, and is not traversed.						GO:0000063		biological_process											owl:Class	
GO:0014895	biolink:NamedThing	smooth muscle hypertrophy	The enlargement or overgrowth of all or part of an organ due to an increase in size of its smooth muscle cells without cell division. Physiological hypertrophy is a normal process during development, and can also occur in mature structures on demand. In the uterus, smooth muscle cells undergo hypertrophy during pregnancy.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0014805	biolink:NamedThing	smooth muscle adaptation	Any process in which smooth muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. These adaptive events occur in both muscle fibers and associated structures (motoneurons and capillaries), and they involve alterations in regulatory mechanisms, contractile properties and metabolic capacities.	tmpzr1t_l9r_go_relaxed.owl	smooth muscle plasticity													biological_process											owl:Class	
GO:0071247	biolink:NamedThing	cellular response to chromate	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chromate stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-12-03T02:46:01Z					biological_process											owl:Class	
GO:0071241	biolink:NamedThing	cellular response to inorganic substance	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an inorganic substance stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-12-03T02:35:49Z					biological_process											owl:Class	
GO:0071297	biolink:NamedThing	cellular response to cobalamin	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cobalamin (vitamin B12) stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to vitamin B12							mah	2009-12-10T04:28:45Z					biological_process											owl:Class	
GO:1901701	biolink:NamedThing	cellular response to oxygen-containing compound	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxygen-containing compound stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to oxygen molecular entity							pr	2012-12-13T15:11:42Z					biological_process											owl:Class	
GO:0048481	biolink:NamedThing	plant ovule development	The process whose specific outcome is the progression of the ovule over time, from its formation to the mature structure. The ovule is the structure in seed plants enclosing the female gametophyte, and is composed of the nucellus, one or two integuments, and the funiculus; it develops into the seed.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0099402	biolink:NamedThing	plant organ development	Development of a plant organ, a multi-tissue plant structure that forms a functional unit.	tmpzr1t_l9r_go_relaxed.owl	development of a plant organ													biological_process											owl:Class	
GO:0047575	biolink:NamedThing	4-carboxymuconolactone decarboxylase activity	Catalysis of the reaction: (R)-2-(carboxymethyl)-5-oxo-2,5-dihydro-2-furoate + H(+) = 5-oxo-4,5-dihydro-2-furylacetate + CO(2).	tmpzr1t_l9r_go_relaxed.owl	4-carboxymuconolactone carboxy-lyase activity|4-carboxymonolactone carboxy-lyase activity|4-carboxymuconolactone carboxy-lyase (4,5-dihydro-5-oxofuran-2-acetate-forming)|gamma-4-carboxymuconolactone decarboxylase activity				EC:4.1.1.44|MetaCyc:4-CARBOXYMUCONOLACTONE-DECARBOXYLASE-RXN|KEGG_REACTION:R03470|RHEA:23348									molecular_function											owl:Class	
GO:0016831	biolink:NamedThing	carboxy-lyase activity	Catalysis of the nonhydrolytic addition or removal of a carboxyl group to or from a compound.	tmpzr1t_l9r_go_relaxed.owl	decarboxylase activity				EC:4.1.1.-|Reactome:R-HSA-71223|Reactome:R-HSA-6814165|Reactome:R-HSA-6787757									molecular_function											owl:Class	
GO:0102346	biolink:NamedThing	3-hydroxy-cerotoyl-CoA dehydratase activity	Catalysis of the reaction: (R)-3-hydroxycerotoyl-CoA(4-) <=> trans-2-hexacosenoyl-CoA(4-) + H2O.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-13305									molecular_function											owl:Class	
GO:0051942	biolink:NamedThing	negative regulation of amino acid uptake involved in synaptic transmission	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of amino acid neurotransmitters into a neuron or glial cell.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of amino acid neurotransmitter uptake|inhibition of amino acid uptake during transmission of nerve impulse|downregulation of amino acid uptake during transmission of nerve impulse|down-regulation of amino acid uptake during transmission of nerve impulse|down regulation of amino acid uptake during transmission of nerve impulse|negative regulation of amino acid uptake during transmission of nerve impulse|negative regulation of amino acid neurotransmitter reuptake													biological_process											owl:Class	
GO:0072564	biolink:NamedThing	blood microparticle formation	The cellular component organization process in which microparticles bud off from a parent cell. A microparticle is a phospholipid microvesicle that is derived from any of several cell types, such as platelets, blood cells, endothelial cells, or others, and contains membrane receptors as well as other proteins characteristic of the parental cell.	tmpzr1t_l9r_go_relaxed.owl	microparticle generation|microparticle release							mah	2011-01-28T02:15:50Z					biological_process											owl:Class	
GO:0016043	biolink:NamedThing	cellular component organization	A process that results in the assembly, arrangement of constituent parts, or disassembly of a cellular component.	tmpzr1t_l9r_go_relaxed.owl	cellular component organisation in other organism|cellular component organization at cellular level|cell organization and biogenesis|cellular component organization in other organism|cellular component organisation at cellular level|cell organisation											GO:0044235|GO:0071842		biological_process											owl:Class	
GO:0050522	biolink:NamedThing	oxidoreductase activity, acting on phosphorus or arsenic in donors, with other known acceptors	Catalysis of an oxidation-reduction (redox) reaction in which phosphorus or arsenic acts as a hydrogen or electron donor and reduces a known acceptor other than disulfide, NAD or NADP.	tmpzr1t_l9r_go_relaxed.owl					EC:1.20.98.-									molecular_function											owl:Class	
GO:0030613	biolink:NamedThing	oxidoreductase activity, acting on phosphorus or arsenic in donors	Catalysis of an oxidation-reduction (redox) reaction in which a phosphorus- or arsenic-containing group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.	tmpzr1t_l9r_go_relaxed.owl	oxidoreductase activity, acting on phosphorus or arsenic in donors, with other acceptors				EC:1.20.-.-									molecular_function											owl:Class	
GO:0033699	biolink:NamedThing	DNA 5'-adenosine monophosphate hydrolase activity	Catalysis of the reaction: 5'-AMP-DNA + H2O = AMP + DNA; nucleophilic release of a covalently linked adenylate residue from a DNA strand, leaving a 5' phosphate terminus.	tmpzr1t_l9r_go_relaxed.owl	DNA deadenylation|AMP-removal activity|DNA 5'-adenylate hydrolase activity|DNA adenylate hydrolysis activity|DNA de-adenylation													molecular_function											owl:Class	
GO:0035312	biolink:NamedThing	5'-3' exodeoxyribonuclease activity	Catalysis of the sequential cleavage of mononucleotides from a free 5' terminus of a DNA molecule.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0008328	biolink:NamedThing	ionotropic glutamate receptor complex	A multimeric assembly of four or five subunits which form a structure with an extracellular N-terminus and a large loop that together form the ligand binding domain. The C-terminus is intracellular. The ionotropic glutamate receptor complex itself acts as a ligand-gated ion channel; on binding glutamate, charged ions pass through a channel in the center of the receptor complex.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0098878	biolink:NamedThing	neurotransmitter receptor complex	Any protein complex that is capable of functioning as a neurotransmitter receptor.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:1990308	biolink:NamedThing	type-I dockerin domain binding	Binding to a type-I dockerin domain of a protein. Type-I dockerin domain is the binding partner of type-1 cohesin domain.	tmpzr1t_l9r_go_relaxed.owl								tt	2014-03-07T03:10:37Z					molecular_function											owl:Class	
GO:0035492	biolink:NamedThing	negative regulation of leukotriene production involved in inflammatory response	Any process that decreases the rate, frequency or extent of the synthesis or release of any leukotriene following a stimulus as part of an inflammatory response.	tmpzr1t_l9r_go_relaxed.owl								bf	2010-04-26T10:50:55Z					biological_process											owl:Class	
GO:0050728	biolink:NamedThing	negative regulation of inflammatory response	Any process that stops, prevents, or reduces the frequency, rate or extent of the inflammatory response.	tmpzr1t_l9r_go_relaxed.owl	down regulation of inflammatory response|inhibition of inflammatory response|downregulation of inflammatory response|down-regulation of inflammatory response|anti-inflammatory response											GO:0030236		biological_process											owl:Class	
GO:0002835	biolink:NamedThing	negative regulation of response to tumor cell	Any process that stops, prevents, or reduces the frequency, rate, or extent of a response to tumor cell.	tmpzr1t_l9r_go_relaxed.owl	inhibition of response to tumor cell|downregulation of response to tumor cell|down-regulation of response to tumor cell|down regulation of response to tumor cell|negative regulation of response to tumour cell													biological_process											owl:Class	
GO:0010958	biolink:NamedThing	regulation of amino acid import across plasma membrane	Any process that modulates the frequency, rate or extent of amino acid import into a cell.	tmpzr1t_l9r_go_relaxed.owl	regulation of amino acid import							tb	2009-05-06T11:33:12Z					biological_process											owl:Class	
GO:0070795	biolink:NamedThing	positive regulation of conidiophore development	Any process that activates or increases the frequency, rate or extent of conidiophore development, a process that leads to the formation of a conidiophore. The conidiophore is a specialized hypha that extends aerially from the growth substrate and bears conidia, or asexual spores.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-07-08T03:08:29Z					biological_process											owl:Class	
GO:0070793	biolink:NamedThing	regulation of conidiophore development	Any process that modulates the frequency, rate or extent of conidiophore development, a process that leads to the formation of a conidiophore. The conidiophore is a specialized hypha that extends aerially from the growth substrate and bears conidia, or asexual spores.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-07-08T03:04:29Z					biological_process											owl:Class	
GO:0071075	biolink:NamedThing	CUGBP1-eIF2 complex	A protein complex that contains the eukaryotic translation initiation factor 2 complex (EIF2), CUG binding protein 1, and several endoplasmic reticulum proteins; the complex is involved in the regulation of translation.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-11-06T01:43:30Z					cellular_component											owl:Class	
GO:0042479	biolink:NamedThing	positive regulation of eye photoreceptor cell development	Any process that activates or increases the frequency, rate or extent of eye photoreceptor development.	tmpzr1t_l9r_go_relaxed.owl	stimulation of eye photoreceptor cell development|activation of eye photoreceptor cell development|up-regulation of eye photoreceptor cell development|up regulation of eye photoreceptor cell development|upregulation of eye photoreceptor cell development|positive regulation of eye photoreceptor development													biological_process											owl:Class	
GO:0010720	biolink:NamedThing	positive regulation of cell development	Any process that increases the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:2000233	biolink:NamedThing	negative regulation of rRNA processing	Any process that stops, prevents, or reduces the frequency, rate or extent of rRNA processing.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of 35S primary transcript processing							mah	2010-11-10T12:11:33Z					biological_process											owl:Class	
GO:0051253	biolink:NamedThing	negative regulation of RNA metabolic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving RNA.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of RNA metabolic process|down regulation of RNA metabolic process|downregulation of RNA metabolic process|inhibition of RNA metabolic process|negative regulation of RNA metabolism													biological_process											owl:Class	
GO:2000569	biolink:NamedThing	regulation of T-helper 2 cell activation	Any process that modulates the frequency, rate or extent of T-helper 2 cell activation.	tmpzr1t_l9r_go_relaxed.owl	regulation of Th2 cell activation							ebc	2011-04-03T09:14:53Z					biological_process											owl:Class	
GO:2000514	biolink:NamedThing	regulation of CD4-positive, alpha-beta T cell activation	Any process that modulates the frequency, rate or extent of CD4-positive, alpha-beta T cell activation.	tmpzr1t_l9r_go_relaxed.owl								ebc	2011-03-22T10:36:56Z					biological_process											owl:Class	
GO:0000209	biolink:NamedThing	protein polyubiquitination	Addition of multiple ubiquitin groups to a protein, forming a ubiquitin chain.	tmpzr1t_l9r_go_relaxed.owl	protein polyubiquitylation|protein polyubiquitinylation|polyubiquitin													biological_process											owl:Class	
GO:0016567	biolink:NamedThing	protein ubiquitination	The process in which one or more ubiquitin groups are added to a protein.	tmpzr1t_l9r_go_relaxed.owl	protein ubiquitinylation|protein ubiquitylation													biological_process											owl:Class	
GO:0045662	biolink:NamedThing	negative regulation of myoblast differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of myoblast differentiation. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.	tmpzr1t_l9r_go_relaxed.owl	inhibition of myoblast differentiation|down regulation of myoblast differentiation|down-regulation of myoblast differentiation|downregulation of myoblast differentiation													biological_process											owl:Class	
GO:0045661	biolink:NamedThing	regulation of myoblast differentiation	Any process that modulates the frequency, rate or extent of myoblast differentiation. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0045835	biolink:NamedThing	negative regulation of meiotic nuclear division	Any process that stops, prevents, or reduces the frequency, rate or extent of meiosis.	tmpzr1t_l9r_go_relaxed.owl	downregulation of meiosis|down-regulation of meiosis|negative regulation of meiosis|inhibition of meiosis|down regulation of meiosis													biological_process											owl:Class	
GO:0051447	biolink:NamedThing	negative regulation of meiotic cell cycle	Any process that stops, prevents or reduces the rate or extent of progression through the meiotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl	inhibition of progression through meiotic cell cycle|down-regulation of progression through meiotic cell cycle|downregulation of progression through meiotic cell cycle|down regulation of progression through meiotic cell cycle|negative regulation of progression through meiotic cell cycle|negative regulation of meiotic cell cycle progression													biological_process											owl:Class	
GO:0052862	biolink:NamedThing	glucan endo-1,4-beta-glucanase activity, C-3 substituted reducing group	Catalysis of the endohydrolysis of (1->4)-linkages in beta-D-glucans when the glucose residue whose reducing group is involved in the linkage to be hydrolysed is itself substituted at C-3.	tmpzr1t_l9r_go_relaxed.owl	laminaranase activity|laminarinase activity|1,3-(1,4)-beta-D-glucan 4-glucanohydrolase activity				MetaCyc:3.2.1.6-RXN|EC:3.2.1.6			ai	2011-12-06T05:27:26Z					molecular_function											owl:Class	
GO:0052736	biolink:NamedThing	beta-glucanase activity	Catalysis of the hydrolysis of linkages in beta-D-glucans; beta-glucans are polysaccharides of D-glucose monomers linked by beta-glycosidic bonds.	tmpzr1t_l9r_go_relaxed.owl	beta-D-glucanase activity								2011-08-19T03:40:56Z					molecular_function											owl:Class	
GO:0021551	biolink:NamedThing	central nervous system morphogenesis	The process in which the anatomical structure of the central nervous system is generated and organized. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain and spinal cord. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0006463	biolink:NamedThing	steroid hormone receptor complex assembly	The aggregation, arrangement and bonding together of a set of components to form a steroid hormone receptor complex, an intracellular receptor that binds steroid hormones. The complex is often a dimer, and forms after the steroid has bound the receptor.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0034622	biolink:NamedThing	cellular protein-containing complex assembly	The aggregation, arrangement and bonding together of a set of components to form a protein complex, occurring at the level of an individual cell.	tmpzr1t_l9r_go_relaxed.owl	cellular protein complex assembly|cellular macromolecule complex assembly											GO:0043623		biological_process											owl:Class	
GO:0043583	biolink:NamedThing	ear development	The process whose specific outcome is the progression of the ear over time, from its formation to the mature structure. The ear is the sense organ in vertebrates that is specialized for the detection of sound, and the maintenance of balance. Includes the outer ear and middle ear, which collect and transmit sound waves; and the inner ear, which contains the organs of balance and (except in fish) hearing. Also includes the pinna, the visible part of the outer ear, present in some mammals.	tmpzr1t_l9r_go_relaxed.owl	hearing organ development													biological_process											owl:Class	
GO:0007423	biolink:NamedThing	sensory organ development	The process whose specific outcome is the progression of sensory organs over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl	sense organ development													biological_process											owl:Class	
GO:0002858	biolink:NamedThing	regulation of natural killer cell mediated cytotoxicity directed against tumor cell target	Any process that modulates the frequency, rate, or extent of natural killer cell mediated cytotoxicity directed against tumor cell target.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1990814	biolink:NamedThing	DNA/DNA annealing activity	An activity that faciliates the formation of a complementary double-stranded DNA molecule.	tmpzr1t_l9r_go_relaxed.owl	DNA reannealing activity	https://github.com/geneontology/go-ontology/issues/2161						vw	2015-07-29T12:35:03Z					molecular_function											owl:Class	
GO:0140666	biolink:NamedThing	annealing activity	An activity that facilitates the formation of a complementary double-stranded polynucleotide molecule.	tmpzr1t_l9r_go_relaxed.owl	renaturation	https://github.com/geneontology/go-ontology/issues/21614						pr	2014-06-13T10:18:43Z			GO:0097617		molecular_function											owl:Class	
GO:1900613	biolink:NamedThing	F-9775B catabolic process	The chemical reactions and pathways resulting in the breakdown of F-9775B.	tmpzr1t_l9r_go_relaxed.owl	F-9775B catabolism|F-9775B degradation|F-9775B breakdown							di	2012-05-15T07:03:24Z					biological_process											owl:Class	
GO:1901377	biolink:NamedThing	organic heteropentacyclic compound catabolic process	The chemical reactions and pathways resulting in the breakdown of organic heteropentacyclic compound.	tmpzr1t_l9r_go_relaxed.owl	organic heteropentacyclic compound breakdown|organic heteropentacyclic compound catabolism|organic heteropentacyclic compound degradation							bf	2012-09-28T12:51:51Z					biological_process											owl:Class	
GO:0097196	biolink:NamedThing	Shu complex	A protein complex involved in error-free DNA post-replication repair (PRR). In Saccharomyces cerevisiae the complex contains Csm2p, Psy3p, Shu1p, and Shu2p.	tmpzr1t_l9r_go_relaxed.owl								pr	2011-12-01T05:11:08Z					cellular_component											owl:Class	
GO:1990391	biolink:NamedThing	DNA repair complex	A protein complex involved in DNA repair processes including direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway.	tmpzr1t_l9r_go_relaxed.owl	DNA damage repair complex|WHY1 complex							bhm	2014-06-04T09:15:24Z					cellular_component											owl:Class	
GO:0043451	biolink:NamedThing	alkene catabolic process	The chemical reactions and pathways resulting in the breakdown of an alkene, any acyclic branched or unbranched hydrocarbon having one carbon-carbon double bond and the general formula CnH2n.	tmpzr1t_l9r_go_relaxed.owl	alkene breakdown|alkene degradation|alkene catabolism													biological_process											owl:Class	
GO:0043449	biolink:NamedThing	cellular alkene metabolic process	The chemical reactions and pathways involving an alkene, any acyclic branched or unbranched hydrocarbon having one carbon-carbon double bond and the general formula CnH2n, as carried out by individual cells.	tmpzr1t_l9r_go_relaxed.owl	alkene metabolism													biological_process											owl:Class	
GO:1904266	biolink:NamedThing	regulation of Schwann cell chemotaxis	Any process that modulates the frequency, rate or extent of Schwann cell chemotaxis.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-05-28T17:47:41Z					biological_process											owl:Class	
GO:0050920	biolink:NamedThing	regulation of chemotaxis	Any process that modulates the frequency, rate or extent of the directed movement of a motile cell or organism in response to a specific chemical concentration gradient.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0019619	biolink:NamedThing	3,4-dihydroxybenzoate catabolic process	The chemical reactions and pathways resulting in the breakdown of  3,4-dihydroxybenzoate.	tmpzr1t_l9r_go_relaxed.owl	protocatechuate degradation|protocatechuate catabolic process|protocatechuate breakdown|protocatechuate catabolism													biological_process											owl:Class	
GO:0034362	biolink:NamedThing	low-density lipoprotein particle	A lipoprotein particle, rich in cholesterol esters and low in triglycerides that is typically composed of APOB100 and APOE and has a density of 1.02-1.06 g/ml and a diameter of between 20-25 nm. LDL particles are formed from VLDL particles (via IDL) by the loss of triglyceride and gain of cholesterol ester. They transport endogenous cholesterol (and to some extent triglycerides) from peripheral tissues back to the liver.	tmpzr1t_l9r_go_relaxed.owl	LDL particle|LDL complex|low-density lipoprotein complex													cellular_component											owl:Class	
GO:0034358	biolink:NamedThing	plasma lipoprotein particle	A spherical particle with a hydrophobic core of triglycerides and/or cholesterol esters, surrounded by an amphipathic monolayer of phospholipids, cholesterol and apolipoproteins. Plasma lipoprotein particles transport lipids, which are non-covalently associated with the particles, in the blood or lymph.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0032819	biolink:NamedThing	positive regulation of natural killer cell proliferation	Any process that activates or increases the frequency, rate or extent of natural killer cell proliferation.	tmpzr1t_l9r_go_relaxed.owl	stimulation of natural killer cell proliferation|up-regulation of natural killer cell proliferation|upregulation of natural killer cell proliferation|up regulation of natural killer cell proliferation|activation of natural killer cell proliferation|positive regulation of NK cell proliferation													biological_process											owl:Class	
GO:0032817	biolink:NamedThing	regulation of natural killer cell proliferation	Any process that modulates the frequency, rate or extent of natural killer cell proliferation.	tmpzr1t_l9r_go_relaxed.owl	regulation of NK cell proliferation													biological_process											owl:Class	
GO:0071541	biolink:NamedThing	eukaryotic translation initiation factor 3 complex, eIF3m	An eukaryotic translation initiation factor 3 complex that contains the PCI-domain protein eIF3m.	tmpzr1t_l9r_go_relaxed.owl	eIF3m-containing eukaryotic translation initiation factor 3 complex							mah	2010-01-12T02:26:41Z					cellular_component											owl:Class	
GO:0005852	biolink:NamedThing	eukaryotic translation initiation factor 3 complex	A complex of several polypeptides that plays at least two important roles in protein synthesis: First, eIF3 binds to the 40S ribosome and facilitates loading of the Met-tRNA/eIF2.GTP ternary complex to form the 43S preinitiation complex. Subsequently, eIF3 apparently assists eIF4 in recruiting mRNAs to the 43S complex. The eIF3 complex contains five conserved core subunits, and may contain several additional proteins; the non-core subunits are thought to mediate association of the complex with specific sets of mRNAs.	tmpzr1t_l9r_go_relaxed.owl	eIF-3|eIF3													cellular_component											owl:Class	
GO:0086046	biolink:NamedThing	membrane depolarization during SA node cell action potential	The process in which SA node cardiac muscle cell membrane potential changes in the depolarizing direction from the negative resting potential towards the positive membrane potential that will be the peak of the action potential.	tmpzr1t_l9r_go_relaxed.owl	membrane depolarization involved in regulation of SAN cardiac muscle cell action potential|membrane depolarization involved in regulation of SA node cardiac muscle cell action potential|membrane depolarization involved in regulation of sinoatrial node cardiac muscle cell action potential|membrane depolarization involved in regulation of sinus node cardiac muscle cell action potential							dph	2011-11-16T10:52:57Z					biological_process											owl:Class	
GO:0051899	biolink:NamedThing	membrane depolarization	The process in which membrane potential decreases with respect to its steady-state potential, usually from negative potential to a more positive potential. For example, the initial depolarization during the rising phase of an action potential is in the direction from the negative steady-state resting potential towards the positive membrane potential that will be the peak of the action potential.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:2000815	biolink:NamedThing	regulation of mRNA stability involved in response to oxidative stress	A process of regulation of mRNA stability that is involved in a response to oxidative stress.	tmpzr1t_l9r_go_relaxed.owl								mah	2011-07-11T04:40:56Z					biological_process											owl:Class	
GO:0010610	biolink:NamedThing	regulation of mRNA stability involved in response to stress	Any process that modulates the propensity of mRNA molecules to degradation that is part of a change in state or activity of a cell as a result of an exogenous disturbance.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1902248	biolink:NamedThing	5-O-phosphono-alpha-D-ribofuranosyl diphosphate binding	Binding to 5-O-phosphono-alpha-D-ribofuranosyl diphosphate.	tmpzr1t_l9r_go_relaxed.owl	5-phosphoribose 1-diphosphate binding|phosphoribosylpyrophosphate binding							mah	2013-06-20T16:20:29Z					molecular_function											owl:Class	
GO:0097367	biolink:NamedThing	carbohydrate derivative binding	Binding to a carbohydrate derivative.	tmpzr1t_l9r_go_relaxed.owl								pr	2012-08-02T13:03:39Z					molecular_function											owl:Class	
GO:0000462	biolink:NamedThing	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	Any process involved in the maturation of a precursor Small SubUnit (SSU) ribosomal RNA (rRNA) molecule into a mature SSU-rRNA molecule from the pre-rRNA molecule originally produced as a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, 5.8S rRNA, and the Large Subunit (LSU) in that order from 5' to 3' along the primary transcript.	tmpzr1t_l9r_go_relaxed.owl	maturation of 18S rRNA											GO:1990041		biological_process											owl:Class	
GO:0030490	biolink:NamedThing	maturation of SSU-rRNA	Any process involved in the maturation of a precursor Small SubUnit (SSU) ribosomal RNA (rRNA) molecule into a mature SSU-rRNA molecule.	tmpzr1t_l9r_go_relaxed.owl	processing of 20S pre-rRNA|SSU-rRNA maturation													biological_process											owl:Class	
GO:1903755	biolink:NamedThing	positive regulation of SUMO transferase activity	Any process that activates or increases the frequency, rate or extent of SUMO transferase activity.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of SUMO conjugating enzyme activity|activation of SUMO transferase activity|up-regulation of SUMO transferase activity|up-regulation of SMT3 conjugating enzyme|upregulation of SUMO conjugating enzyme activity|upregulation of SMT3 conjugating enzyme|positive regulation of SUMO conjugating enzyme activity|upregulation of SUMO transferase activity|up regulation of SMT3 conjugating enzyme|up regulation of SUMO conjugating enzyme activity|activation of SUMO conjugating enzyme activity|positive regulation of SMT3 conjugating enzyme|up regulation of SUMO transferase activity|activation of SMT3 conjugating enzyme							rl	2014-12-18T13:05:59Z					biological_process											owl:Class	
GO:1903182	biolink:NamedThing	regulation of SUMO transferase activity	Any process that modulates the frequency, rate or extent of SUMO ligase activity.	tmpzr1t_l9r_go_relaxed.owl	regulation of SUMO conjugating enzyme activity|regulation of SMT3 conjugating enzyme							bf	2014-07-14T14:01:40Z					biological_process											owl:Class	
GO:1903448	biolink:NamedThing	geraniol biosynthetic process	The chemical reactions and pathways resulting in the formation of geraniol.	tmpzr1t_l9r_go_relaxed.owl	geraniol synthesis|geraniol anabolism|geraniol biosynthesis|geraniol formation							di	2014-09-19T08:18:52Z					biological_process											owl:Class	
GO:0120255	biolink:NamedThing	olefinic compound biosynthetic process	The chemical reactions and pathways resulting in the formation of an olefinic compound, any compound which contains a carbon-carbon double bond (aka C=C).	tmpzr1t_l9r_go_relaxed.owl	alkene substituted compound biosynthetic process|alkene substituted compound synthesis|alkene substituted compound anabolism|alkene substituted compound anabolic process|alkene substituted compound biosynthesis	https://github.com/geneontology/go-ontology/issues/19936						krc	2020-09-02T23:30:20Z					biological_process											owl:Class	
GO:1903634	biolink:NamedThing	negative regulation of leucine-tRNA ligase activity	Any process that stops, prevents or reduces the frequency, rate or extent of leucine-tRNA ligase activity.	tmpzr1t_l9r_go_relaxed.owl	down regulation of leucyl-tRNA synthetase activity|negative regulation of leucine-tRNA synthetase activity|downregulation of L-leucine:tRNALeu ligase (AMP-forming)|down regulation of leucyl-transfer ribonucleate synthetase activity|inhibition of leucyl-transfer ribonucleic acid synthetase activity|inhibition of leucyl-transfer RNA synthetase activity|negative regulation of leucine translase activity|down regulation of leucine-tRNA ligase activity|down regulation of L-leucine:tRNALeu ligase (AMP-forming)|inhibition of leucine-tRNA ligase activity|downregulation of leucine translase activity|down-regulation of leucyl-tRNA synthetase activity|down-regulation of leucyl-transfer ribonucleate synthetase activity|negative regulation of leucyl-transfer ribonucleate synthetase activity|downregulation of leucine-tRNA synthetase activity|inhibition of leucine-tRNA synthetase activity|down-regulation of leucyl-transfer RNA synthetase activity|inhibition of leucyl-transfer ribonucleate synthetase activity|negative regulation of leucyl-transfer RNA synthetase activity|down-regulation of L-leucine:tRNALeu ligase (AMP-forming)|down regulation of leucine-tRNA synthetase activity|down-regulation of leucyl-transfer ribonucleic acid synthetase activity|downregulation of leucyl-transfer ribonucleate synthetase activity|downregulation of leucyl-tRNA synthetase activity|down-regulation of leucine translase activity|negative regulation of leucyl-tRNA synthetase activity|inhibition of L-leucine:tRNALeu ligase (AMP-forming)|down regulation of leucyl-transfer RNA synthetase activity|inhibition of leucine translase activity|down regulation of leucine translase activity|negative regulation of leucyl-transfer ribonucleic acid synthetase activity|down-regulation of leucine-tRNA synthetase activity|downregulation of leucyl-transfer RNA synthetase activity|downregulation of leucyl-transfer ribonucleic acid synthetase activity|down-regulation of leucine-tRNA ligase activity|negative regulation of L-leucine:tRNALeu ligase (AMP-forming)|inhibition of leucyl-tRNA synthetase activity|down regulation of leucyl-transfer ribonucleic acid synthetase activity|downregulation of leucine-tRNA ligase activity							sl	2014-11-20T00:24:56Z					biological_process											owl:Class	
GO:1903631	biolink:NamedThing	negative regulation of aminoacyl-tRNA ligase activity	Any process that stops, prevents or reduces the frequency, rate or extent of aminoacyl-tRNA ligase activity.	tmpzr1t_l9r_go_relaxed.owl	inhibition of aminoacyl-tRNA synthetase activity|inhibition of aminoacyl-tRNA ligase activity|down-regulation of aminoacyl-tRNA synthetase activity|inhibition of aminoacyl-tRNA synthetase auxiliary protein activity|downregulation of aminoacyl-tRNA ligase activity|negative regulation of aminoacyl-tRNA synthetase activity|negative regulation of aminoacyl-tRNA synthetase auxiliary protein activity|downregulation of aminoacyl-tRNA synthetase activity|down regulation of aminoacyl-tRNA synthetase auxiliary protein activity|down-regulation of aminoacyl-tRNA ligase activity|down-regulation of aminoacyl-tRNA synthetase auxiliary protein activity|down regulation of aminoacyl-tRNA ligase activity|downregulation of aminoacyl-tRNA synthetase auxiliary protein activity|down regulation of aminoacyl-tRNA synthetase activity							sl	2014-11-20T00:22:12Z					biological_process											owl:Class	
GO:0005999	biolink:NamedThing	xylulose biosynthetic process	The chemical reactions and pathways resulting in the formation of xylulose, the ketopentose threo-2-pentulose.	tmpzr1t_l9r_go_relaxed.owl	xylulose anabolism|xylulose biosynthesis|xylulose synthesis|xylulose formation													biological_process											owl:Class	
GO:0005997	biolink:NamedThing	xylulose metabolic process	The chemical reactions and pathways involving xylulose, the ketopentose threo-2-pentulose.	tmpzr1t_l9r_go_relaxed.owl	xylulose metabolism													biological_process											owl:Class	
GO:2000754	biolink:NamedThing	regulation of sphingomyelin catabolic process	Any process that modulates the frequency, rate or extent of sphingomyelin catabolic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of sphingomyelin catabolism|regulation of sphingomyelin degradation|regulation of sphingomyelin breakdown							rl	2011-06-16T03:17:30Z					biological_process											owl:Class	
GO:0035554	biolink:NamedThing	termination of Roundabout signal transduction	The signaling process in which signaling from the receptor ROBO is brought to an end, rather than being reversibly modulated.	tmpzr1t_l9r_go_relaxed.owl								bf	2010-05-14T11:08:12Z					biological_process											owl:Class	
GO:0023021	biolink:NamedThing	termination of signal transduction	The signaling process in which signal transduction is brought to an end rather than being reversibly modulated.	tmpzr1t_l9r_go_relaxed.owl						Note that this term encompasses both the control point when the instruction is given for the process to cease and the actual cessation of the process. A process can persist for some time after that signal that induced the process is withdrawn.			2010-02-16T09:30:50Z					biological_process											owl:Class	
GO:0032657	biolink:NamedThing	regulation of interleukin-14 production	Any process that modulates the frequency, rate, or extent of interleukin-14 production.	tmpzr1t_l9r_go_relaxed.owl	regulation of interleukin-14 biosynthetic process|regulation of IL-14 production											GO:0045369		biological_process											owl:Class	
GO:0001817	biolink:NamedThing	regulation of cytokine production	Any process that modulates the frequency, rate, or extent of production of a cytokine.	tmpzr1t_l9r_go_relaxed.owl	regulation of cytokine synthesis|regulation of cytokine biosynthesis|regulation of cytokine formation|regulation of cytokine secretion|regulation of cytokine biosynthetic process|regulation of cytokine anabolism											GO:0050707|GO:0042035		biological_process											owl:Class	
GO:0048624	biolink:NamedThing	plantlet formation on parent plant	The process in which a new plantlet develops from a meristem on the plant body. As part of this process, when the plantlet is large enough to live independently, the physical connection between the new plantlet and the main plant is severed.	tmpzr1t_l9r_go_relaxed.owl	vegetative vivipary|vivipary													biological_process											owl:Class	
GO:0044706	biolink:NamedThing	multi-multicellular organism process	A multicellular organism process which involves another multicellular organism of the same or different species.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/21459						jl	2012-09-19T16:06:16Z					biological_process											owl:Class	
GO:1904202	biolink:NamedThing	negative regulation of iodide transport	Any process that stops, prevents or reduces the frequency, rate or extent of iodide transport.	tmpzr1t_l9r_go_relaxed.owl	inhibition of iodide transport|down-regulation of iodide transport|down regulation of iodide transport|downregulation of iodide transport							sl	2015-05-08T15:20:03Z					biological_process											owl:Class	
GO:2000397	biolink:NamedThing	positive regulation of ubiquitin-dependent endocytosis	Any process that activates or increases the frequency, rate or extent of ubiquitin-dependent endocytosis.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of ubiquitin-mediated endocytosis							mah	2011-02-22T11:25:42Z					biological_process											owl:Class	
GO:0004129	biolink:NamedThing	cytochrome-c oxidase activity	Catalysis of the reaction: 4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.	tmpzr1t_l9r_go_relaxed.owl	complex IV (mitochondrial electron transport) activity|indophenol oxidase|Warburg's respiratory enzyme activity|aa3-type cytochrome c oxidase|cytochrome oxidase activity|cytochrome aa3 activity|indophenolase|caa3-type cytochrome c oxidase|cytochrome a3 activity|cytochrome c oxidase activity|ba3-type cytochrome c oxidase|cbb3-type cytochrome c oxidase	https://github.com/geneontology/go-ontology/issues/20924|https://github.com/geneontology/go-ontology/issues/21275			Reactome:R-HSA-163214|EC:7.1.1.9|MetaCyc:CYTOCHROME-C-OXIDASE-RXN|RHEA:11436	The reduction of O2 to water is accompanied by the extrusion of four protons from the intramitochondrial compartment.								molecular_function											owl:Class	
GO:0009055	biolink:NamedThing	electron transfer activity	Any molecular entity that serves as an electron acceptor and electron donor in an electron transport chain. An electron transport chain is a process in which a series of electron carriers operate together to transfer electrons from donors to any of several different terminal electron acceptors to generate a transmembrane electrochemical gradient.	tmpzr1t_l9r_go_relaxed.owl	electron transporter activity|electron donor activity|electron acceptor activity|electron carrier	https://github.com/geneontology/go-ontology/issues/21334			Reactome:R-HSA-169260|Reactome:R-HSA-2564826	Note that this term should only be be used for electron transfer that generates a transmembrane electrochemical gradient, e.g. components of the respiratory or photosynthetic electron transport chain.						GO:0009054|GO:0009053		molecular_function											owl:Class	
GO:0051098	biolink:NamedThing	regulation of binding	Any process that modulates the frequency, rate or extent of binding, the selective interaction of a molecule with one or more specific sites on another molecule.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1900984	biolink:NamedThing	vindoline catabolic process	The chemical reactions and pathways resulting in the breakdown of vindoline.	tmpzr1t_l9r_go_relaxed.owl	vindoline catabolism|vindoline degradation|vindoline breakdown							yaf	2012-06-14T09:16:56Z					biological_process											owl:Class	
GO:0009822	biolink:NamedThing	alkaloid catabolic process	The chemical reactions and pathways resulting in the breakdown of alkaloids, nitrogen containing natural products not otherwise classified as peptides, nonprotein amino acids, amines, cyanogenic glycosides, glucosinolates, cofactors, phytohormones or primary metabolites (such as purine or pyrimidine bases).	tmpzr1t_l9r_go_relaxed.owl	alkaloid degradation|alkaloid breakdown|alkaloid catabolism													biological_process											owl:Class	
GO:0140499	biolink:NamedThing	negative regulation of mitotic spindle assembly checkpoint signaling	Any process that stops, prevents, or reduces the frequency, rate or extent of negative regulation of mitotic spindle assembly checkpoint signaling.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/19818						pg	2020-07-22T15:44:06Z					biological_process											owl:Class	
GO:0062033	biolink:NamedThing	positive regulation of mitotic sister chromatid segregation	Any process that starts or increases the frequency, rate or extent of sister chromatid segregation during mitosis.	tmpzr1t_l9r_go_relaxed.owl								dph	2018-04-23T14:32:23Z					biological_process											owl:Class	
GO:1901105	biolink:NamedThing	tetracenomycin C catabolic process	The chemical reactions and pathways resulting in the breakdown of tetracenomycin C.	tmpzr1t_l9r_go_relaxed.owl	tetracenomycin C catabolism|tetracenomycin C degradation|tetracenomycin C breakdown							yaf	2012-07-11T02:50:54Z					biological_process											owl:Class	
GO:1902759	biolink:NamedThing	Mo(VI)-molybdopterin cytosine dinucleotide metabolic process	The chemical reactions and pathways involving Mo(VI)-molybdopterin cytosine dinucleotide.	tmpzr1t_l9r_go_relaxed.owl	Mo(VI)-molybdopterin cytosine dinucleotide metabolism							dph	2014-03-06T14:00:31Z					biological_process											owl:Class	
GO:0009117	biolink:NamedThing	nucleotide metabolic process	The chemical reactions and pathways involving a nucleotide, a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the glycose moiety; may be mono-, di- or triphosphate; this definition includes cyclic nucleotides (nucleoside cyclic phosphates).	tmpzr1t_l9r_go_relaxed.owl	nucleotide metabolism													biological_process											owl:Class	
GO:0000828	biolink:NamedThing	inositol hexakisphosphate kinase activity	Catalysis of the reaction: ATP + 1D-myo-inositol 1,2,3,4,5,6-hexakisphosphate = ADP + diphospho-1D-myo-inositol-pentakisphosphate. The isomeric configuration of diphospho-1D-myo-inositol-pentakisphosphate (PP-IP5) is unknown.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-1855216|Reactome:R-HSA-1855207|Reactome:R-HSA-1855227									molecular_function											owl:Class	
GO:0016301	biolink:NamedThing	kinase activity	Catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.	tmpzr1t_l9r_go_relaxed.owl	phosphokinase activity				Reactome:R-HSA-6788855|Reactome:R-HSA-6788867	Note that this term encompasses all activities that transfer a single phosphate group; although ATP is by far the most common phosphate donor, reactions using other phosphate donors are included in this term.								molecular_function											owl:Class	
GO:0031978	biolink:NamedThing	plastid thylakoid lumen	The volume enclosed by a plastid thylakoid membrane.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0031977	biolink:NamedThing	thylakoid lumen	The volume enclosed by a thylakoid membrane.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:1905675	biolink:NamedThing	negative regulation of adaptive immune memory response	Any process that stops, prevents or reduces the frequency, rate or extent of adaptive immune memory response.	tmpzr1t_l9r_go_relaxed.owl	inhibition of adaptive immune memory response|down regulation of adaptive immune memory response|down-regulation of adaptive immune memory response|downregulation of adaptive immune memory response							tb	2016-11-11T22:24:41Z					biological_process											owl:Class	
GO:0002820	biolink:NamedThing	negative regulation of adaptive immune response	Any process that stops, prevents, or reduces the frequency, rate, or extent of an adaptive immune response.	tmpzr1t_l9r_go_relaxed.owl	inhibition of adaptive immune response|down regulation of adaptive immune response|down-regulation of adaptive immune response|downregulation of adaptive immune response													biological_process											owl:Class	
GO:2000913	biolink:NamedThing	negative regulation of galactoglucomannan catabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of galactoglucomannan catabolic process.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of galactoglucomannan catabolism							tt	2011-07-29T07:51:41Z					biological_process											owl:Class	
GO:0006082	biolink:NamedThing	organic acid metabolic process	The chemical reactions and pathways involving organic acids, any acidic compound containing carbon in covalent linkage.	tmpzr1t_l9r_go_relaxed.owl	organic acid metabolism													biological_process											owl:Class	
GO:1903952	biolink:NamedThing	regulation of voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization	Any process that modulates the frequency, rate or extent of voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization.	tmpzr1t_l9r_go_relaxed.owl	regulation of voltage-gated potassium channel activity involved in atrial cardiomyocyte action potential repolarization							nc	2015-02-24T10:32:06Z					biological_process											owl:Class	
GO:1905031	biolink:NamedThing	regulation of membrane repolarization during cardiac muscle cell action potential	Any process that modulates the frequency, rate or extent of membrane repolarization during cardiac muscle cell action potential.	tmpzr1t_l9r_go_relaxed.owl								rph	2016-03-07T10:24:34Z					biological_process											owl:Class	
GO:0033615	biolink:NamedThing	mitochondrial proton-transporting ATP synthase complex assembly	The aggregation, arrangement and bonding together of a proton-transporting ATP synthase in the mitochondrial inner membrane.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0043461	biolink:NamedThing	proton-transporting ATP synthase complex assembly	The aggregation, arrangement and bonding together of a proton-transporting ATP synthase (also known as F-type ATPase), a two-sector ATPase found in the inner membrane of mitochondria and chloroplasts, and in bacterial plasma membranes.	tmpzr1t_l9r_go_relaxed.owl	F-type ATPase complex assembly													biological_process											owl:Class	
GO:1902261	biolink:NamedThing	positive regulation of delayed rectifier potassium channel activity	Any process that activates or increases the frequency, rate or extent of delayed rectifier potassium channel activity.	tmpzr1t_l9r_go_relaxed.owl	activation of delayed rectifier potassium channel activity|up regulation of delayed rectifier potassium channel activity|upregulation of delayed rectifier potassium channel activity|up-regulation of delayed rectifier potassium channel activity							rl	2013-06-25T12:16:30Z					biological_process											owl:Class	
GO:1902259	biolink:NamedThing	regulation of delayed rectifier potassium channel activity	Any process that modulates the frequency, rate or extent of delayed rectifier potassium channel activity.	tmpzr1t_l9r_go_relaxed.owl								rl	2013-06-25T12:16:19Z					biological_process											owl:Class	
GO:0060168	biolink:NamedThing	positive regulation of adenosine receptor signaling pathway	Any process that activates or increases the frequency, rate or extent of the adenosine receptor signaling pathway. The adenosine receptor pathway is the series of molecular signals generated as a consequence of an adenosine receptor binding to one of its physiological ligands.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of adenosine receptor signalling pathway													biological_process											owl:Class	
GO:0045745	biolink:NamedThing	positive regulation of G protein-coupled receptor signaling pathway	Any process that activates or increases the frequency, rate or extent of G protein-coupled receptor signaling pathway activity.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of G protein coupled receptor protein signaling pathway|positive regulation of G-protein coupled receptor protein signalling pathway|positive regulation of GPCR protein signalling pathway|positive regulation of G protein coupled receptor protein signalling pathway|upregulation of G-protein coupled receptor protein signaling pathway|positive regulation of GPCR protein signaling pathway|positive regulation of G-protein-coupled receptor protein signaling pathway|up-regulation of G-protein coupled receptor protein signaling pathway|up regulation of G-protein coupled receptor protein signaling pathway|stimulation of G-protein coupled receptor protein signaling pathway|positive regulation of G-protein coupled receptor protein signaling pathway|positive regulation of G-protein-coupled receptor protein signalling pathway|activation of G-protein coupled receptor protein signaling pathway													biological_process											owl:Class	
GO:0042104	biolink:NamedThing	positive regulation of activated T cell proliferation	Any process that activates or increases the rate or extent of activated T cell proliferation.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of activated T-cell proliferation|upregulation of activated T cell proliferation|stimulation of activated T cell proliferation|positive regulation of activated T lymphocyte proliferation|positive regulation of activated T-lymphocyte proliferation|up-regulation of activated T cell proliferation|activation of activated T cell proliferation|up regulation of activated T cell proliferation													biological_process											owl:Class	
GO:0042102	biolink:NamedThing	positive regulation of T cell proliferation	Any process that activates or increases the rate or extent of T cell proliferation.	tmpzr1t_l9r_go_relaxed.owl	stimulation of T cell proliferation|up-regulation of T cell proliferation|positive regulation of T-lymphocyte proliferation|positive regulation of T lymphocyte proliferation|activation of T cell proliferation|upregulation of T cell proliferation|up regulation of T cell proliferation													biological_process											owl:Class	
GO:0080151	biolink:NamedThing	positive regulation of salicylic acid mediated signaling pathway	Any process that activates or increases the frequency, rate or extent of salicylic acid mediated signal transduction.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of salicylic acid mediated signalling pathway							dhl	2010-05-20T03:10:46Z					biological_process											owl:Class	
GO:2000031	biolink:NamedThing	regulation of salicylic acid mediated signaling pathway	Any process that modulates the frequency, rate or extent of salicylic acid mediated signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	regulation of salicylic acid mediated signalling pathway							tb	2010-08-05T11:32:24Z					biological_process											owl:Class	
GO:0009242	biolink:NamedThing	colanic acid biosynthetic process	The chemical reactions and pathways resulting in the formation of colanic acid, a capsular bacterial polysaccharide.	tmpzr1t_l9r_go_relaxed.owl	colanic acid formation|colanic acid synthesis|colanic acid anabolism|M antigen biosynthesis|colanic acid biosynthesis|M antigen biosynthetic process				MetaCyc:COLANSYN-PWY									biological_process											owl:Class	
GO:0046377	biolink:NamedThing	colanic acid metabolic process	The chemical reactions and pathways involving colanic acid, a capsular bacterial polysaccharide composed of glucose, galactose, fucose and glucuronic acid residues.	tmpzr1t_l9r_go_relaxed.owl	colanic acid metabolism													biological_process											owl:Class	
GO:0099639	biolink:NamedThing	neurotransmitter receptor transport, endosome to plasma membrane	The directed movement of neurotransmitter receptor from the endosome to the plasma membrane in transport vesicles.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0098877	biolink:NamedThing	neurotransmitter receptor transport to plasma membrane	The directed movement of neurotransmitter receptor to the plasma membrane in transport vesicles.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0046086	biolink:NamedThing	adenosine biosynthetic process	The chemical reactions and pathways resulting in the formation of adenosine, adenine riboside, a ribonucleoside found widely distributed in cells of every type as the free nucleoside and in combination in nucleic acids and various nucleoside coenzymes.	tmpzr1t_l9r_go_relaxed.owl	adenosine anabolism|adenosine biosynthesis|adenosine formation|adenosine synthesis													biological_process											owl:Class	
GO:0046129	biolink:NamedThing	purine ribonucleoside biosynthetic process	The chemical reactions and pathways resulting in the formation of any purine ribonucleoside, a nucleoside in which purine base is linked to a ribose (beta-D-ribofuranose) molecule.	tmpzr1t_l9r_go_relaxed.owl	purine ribonucleoside formation|purine ribonucleoside synthesis|purine ribonucleoside anabolism|purine ribonucleoside biosynthesis													biological_process											owl:Class	
GO:1903250	biolink:NamedThing	positive regulation of citrulline biosynthetic process	Any process that activates or increases the frequency, rate or extent of citrulline biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	activation of citrulline synthesis|upregulation of citrulline synthesis|up-regulation of citrulline formation|activation of citrulline biosynthetic process|up-regulation of citrulline biosynthetic process|up regulation of citrulline synthesis|upregulation of citrulline biosynthetic process|positive regulation of citrulline biosynthesis|positive regulation of citrulline synthesis|activation of citrulline formation|up-regulation of citrulline synthesis|upregulation of citrulline formation|up regulation of citrulline formation|up regulation of citrulline biosynthetic process|up-regulation of citrulline anabolism|up-regulation of citrulline biosynthesis|positive regulation of citrulline formation|up regulation of citrulline anabolism|upregulation of citrulline anabolism|upregulation of citrulline biosynthesis|up regulation of citrulline biosynthesis|positive regulation of citrulline anabolism|activation of citrulline anabolism|activation of citrulline biosynthesis							rl	2014-08-04T15:24:52Z					biological_process											owl:Class	
GO:0010645	biolink:NamedThing	regulation of cell communication by chemical coupling	Any process that modulates the frequency, rate or extent of cell communication via chemical coupling. Cell communication by chemical coupling is the process that mediates signaling interactions between one cell and another cell by the transfer of small, water-soluble molecules or metabolites between their adjacent cytoplasms via intercellular protein channels.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0010646	biolink:NamedThing	regulation of cell communication	Any process that modulates the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0102883	biolink:NamedThing	(+)-beta-chamigrene synthase activity	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate <=> (+)-beta-chamigrene + diphosphoric acid.	tmpzr1t_l9r_go_relaxed.owl					RHEA:30379|EC:4.2.3.78|MetaCyc:RXN-8424									molecular_function											owl:Class	
GO:0016838	biolink:NamedThing	carbon-oxygen lyase activity, acting on phosphates	Catalysis of the cleavage of a carbon-oxygen bond by elimination of a phosphate.	tmpzr1t_l9r_go_relaxed.owl					EC:4.2.3.-									molecular_function											owl:Class	
GO:1990742	biolink:NamedThing	microvesicle	An extracellular vesicle released from the plasma membrane and ranging in size from about 100 nm to 1000 nm.	tmpzr1t_l9r_go_relaxed.owl	ectosome|extracellular microvesicle|shedding vesicle							pr	2015-05-13T13:44:52Z					cellular_component											owl:Class	
GO:1903561	biolink:NamedThing	extracellular vesicle	Any vesicle that is part of the extracellular region.	tmpzr1t_l9r_go_relaxed.owl	microparticle							jl	2014-10-22T14:26:11Z					cellular_component											owl:Class	
GO:0060062	biolink:NamedThing	Spemann organizer formation at the dorsal lip of the blastopore	Formation of the specialized region at the dorsal lip of the blatopore of the embryo that acts as the main signaling center establishing the vertebrate body plan.	tmpzr1t_l9r_go_relaxed.owl	Spemann's organizer formation at the dorsal lip of the blastopore|Spemann-Mangold organizer formation at the dorsal lip of the blastopore					Occurs in amphibia, cephalochordates, cyclostomes and cartilaginous fish.								biological_process											owl:Class	
GO:0060061	biolink:NamedThing	Spemann organizer formation	Formation of the specialized region on the dorsalmost side of the embryo that acts as the main signaling center establishing the vertebrate body plan.	tmpzr1t_l9r_go_relaxed.owl	Spemann-Mangold organizer formation|Spemann's organizer formation													biological_process											owl:Class	
GO:1904077	biolink:NamedThing	negative regulation of estrogen biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of estrogen biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	inhibition of estrogen synthesis|negative regulation of estrogen formation|down regulation of estrogen formation|down regulation of estrogen biosynthetic process|down-regulation of oestrogen biosynthetic process|negative regulation of oestrogen biosynthetic process|downregulation of estrogen anabolism|inhibition of estrogen anabolism|downregulation of estrogen biosynthetic process|inhibition of estrogen formation|downregulation of oestrogen biosynthetic process|down-regulation of estrogen biosynthetic process|negative regulation of estrogen synthesis|negative regulation of estrogen anabolism|inhibition of estrogen biosynthesis|down regulation of oestrogen biosynthesis|down regulation of estrogen synthesis|down regulation of oestrogen biosynthetic process|negative regulation of estrogen biosynthesis|inhibition of estrogen biosynthetic process|down-regulation of estrogen synthesis|downregulation of estrogen biosynthesis|downregulation of estrogen synthesis|inhibition of oestrogen biosynthesis|negative regulation of oestrogen biosynthesis|down-regulation of oestrogen biosynthesis|down-regulation of estrogen formation|down regulation of estrogen biosynthesis|down-regulation of estrogen biosynthesis|down regulation of estrogen anabolism|down-regulation of estrogen anabolism|downregulation of oestrogen biosynthesis|downregulation of estrogen formation|inhibition of oestrogen biosynthetic process							tb	2015-03-20T16:56:20Z					biological_process											owl:Class	
GO:1904076	biolink:NamedThing	regulation of estrogen biosynthetic process	Any process that modulates the frequency, rate or extent of estrogen biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of estrogen synthesis|regulation of oestrogen biosynthesis|regulation of estrogen formation|regulation of oestrogen biosynthetic process|regulation of estrogen biosynthesis|regulation of estrogen anabolism							tb	2015-03-20T16:56:14Z					biological_process											owl:Class	
GO:0140492	biolink:NamedThing	metal-dependent deubiquitinase activity	Catalysis of the metal-dependent hydrolysis of an ester, thioester, amide, peptide or isopeptide bond formed by the C-terminal glycine of ubiquitin.	tmpzr1t_l9r_go_relaxed.owl	metal-dependent ubiquitinyl-like hydrolase activity|metal-dependent ubiquitin-like hydrolase activity	https://github.com/geneontology/go-ontology/issues/17398						pg	2020-07-01T13:14:00Z					molecular_function											owl:Class	
GO:0101005	biolink:NamedThing	deubiquitinase activity	Catalysis of the hydrolysis of ubiquitin from proteins.	tmpzr1t_l9r_go_relaxed.owl	ubiquitinyl hydrolase activity	https://github.com/geneontology/go-ontology/issues/17398			Reactome:R-HSA-9674127	There are two main classes of deubiquitinating enzymes: cysteine proteases (i.e., thiol dependent) and metalloproteases.		mec	2016-02-08T09:39:38Z			GO:1904265		molecular_function											owl:Class	
GO:0031762	biolink:NamedThing	follicle-stimulating hormone receptor binding	Binding to a follicle-stimulating hormone receptor.	tmpzr1t_l9r_go_relaxed.owl	FSH receptor binding|follicle stimulating hormone receptor binding|follicle stimulating hormone receptor ligand													molecular_function											owl:Class	
GO:0010395	biolink:NamedThing	rhamnogalacturonan I metabolic process	The chemical reactions and pathways involving rhamnogalacturonan I (RGI), a branched pectin with a backbone of alternating alpha-(1->2)-linked rhamnose and alpha-(1->4)-linked D-galacturonic acid residues that carries neutral side-chains of predominantly beta-(1->4)-D-galactose and/or alpha-(1->5)-L-arabinose residues attached to the rhamnose residues of the RGI backbone.	tmpzr1t_l9r_go_relaxed.owl	RGI metabolism|rhamnogalacturonan I metabolism													biological_process											owl:Class	
GO:0010383	biolink:NamedThing	cell wall polysaccharide metabolic process	The chemical reactions and pathways involving cell wall polysaccharides.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0050747	biolink:NamedThing	positive regulation of lipoprotein metabolic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving lipoproteins, any conjugated, water-soluble protein in which the nonprotein group consists of a lipid or lipids.	tmpzr1t_l9r_go_relaxed.owl	upregulation of lipoprotein metabolic process|positive regulation of lipoprotein metabolism|up regulation of lipoprotein metabolic process|up-regulation of lipoprotein metabolic process|activation of lipoprotein metabolic process|stimulation of lipoprotein metabolic process													biological_process											owl:Class	
GO:1902039	biolink:NamedThing	negative regulation of seed dormancy process	Any process that stops, prevents or reduces the frequency, rate or extent of seed dormancy process.	tmpzr1t_l9r_go_relaxed.owl	inhibition of seed dormancy process|inhibition of seed dormancy|downregulation of seed dormancy|down regulation of seed dormancy process|negative regulation of seed dormancy|down-regulation of seed dormancy process|down regulation of seed dormancy|down-regulation of seed dormancy|downregulation of seed dormancy process							tb	2013-04-02T22:13:15Z					biological_process											owl:Class	
GO:1903607	biolink:NamedThing	cytochrome c biosynthetic process	The chemical reactions and pathways resulting in the formation of cytochrome c.	tmpzr1t_l9r_go_relaxed.owl	cytochrome c synthesis|cytochrome c formation|cytochrome c anabolism|cytochrome c biosynthesis							dph	2014-11-13T20:01:35Z					biological_process											owl:Class	
GO:1903605	biolink:NamedThing	cytochrome biosynthetic process	The chemical reactions and pathways resulting in the formation of a cytochrome.	tmpzr1t_l9r_go_relaxed.owl	cytochrome formation|cytochrome synthesis|cytochrome biosynthesis|cytochrome anabolism							dph	2014-11-13T20:01:18Z					biological_process											owl:Class	
GO:0099079	biolink:NamedThing	actin body	An amorphous cytoskeletal structure consisting of aggregated actin filaments and associated proteins (including fibrin and capping protein) in which there is little or no actin filament turnover.  In yeast (S. pombe and S. cerevisiae) these are found only in quiescent cells and are thought to serve as a reserve store of actin.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:1905245	biolink:NamedThing	regulation of aspartic-type peptidase activity	Any process that modulates the frequency, rate or extent of aspartic-type peptidase activity.	tmpzr1t_l9r_go_relaxed.owl								jl	2016-06-09T11:55:39Z					biological_process											owl:Class	
GO:0052547	biolink:NamedThing	regulation of peptidase activity	Any process that modulates the frequency, rate or extent of peptidase activity, the hydrolysis of peptide bonds within proteins.	tmpzr1t_l9r_go_relaxed.owl	peptidase regulator activity													biological_process											owl:Class	
GO:0000100	biolink:NamedThing	S-methylmethionine transmembrane transporter activity	Enables the transfer of S-methylmethionine from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	S-methylmethionine permease activity|S-methylmethionine transporter activity											GO:0015178		molecular_function											owl:Class	
GO:1901682	biolink:NamedThing	sulfur compound transmembrane transporter activity	Enables the transfer of a sulfur compound from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	sulfur molecular entity transmembrane transporter activity							pr	2012-11-26T20:45:29Z					molecular_function											owl:Class	
GO:0001574	biolink:NamedThing	ganglioside biosynthetic process	The chemical reactions and pathways resulting in the formation of ceramide oligosaccharides carrying in addition to other sugar residues, one or more sialic acid residues.	tmpzr1t_l9r_go_relaxed.owl	ganglioside synthesis|ganglioside anabolism|ganglioside formation|ganglioside biosynthesis													biological_process											owl:Class	
GO:0046513	biolink:NamedThing	ceramide biosynthetic process	The chemical reactions and pathways resulting in the formation of ceramides, any N-acylated sphingoid.	tmpzr1t_l9r_go_relaxed.owl	ceramide biosynthesis|ceramide synthesis|ceramide anabolism|ceramide formation													biological_process											owl:Class	
GO:0002246	biolink:NamedThing	wound healing involved in inflammatory response	The series of events that restore integrity to damaged tissue that contribute to an inflammatory response.	tmpzr1t_l9r_go_relaxed.owl	healing during inflammatory response|inflammatory response wound healing													biological_process											owl:Class	
GO:0042060	biolink:NamedThing	wound healing	The series of events that restore integrity to a damaged tissue, following an injury.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Wound_healing									biological_process											owl:Class	
GO:1903599	biolink:NamedThing	positive regulation of autophagy of mitochondrion	Any process that activates or increases the frequency, rate or extent of mitochondrion degradation by autophagy.	tmpzr1t_l9r_go_relaxed.owl	upregulation of mitophagy|positive regulation of mitochondrial degradation|activation of mitochondrion degradation|up-regulation of mitophagy|up regulation of mitochondrion degradation|up regulation of mitophagy|upregulation of mitochondrion degradation|up-regulation of mitochondrion degradation|activation of mitophagy					An example of this AMBRA1 - human (Q9C0C7) in PMID:21753002 inferred from direct assay		pad	2014-11-10T14:25:53Z					biological_process											owl:Class	
GO:0038118	biolink:NamedThing	C-C chemokine receptor CCR7 signaling pathway	A series of molecular signals initiated by a the C-C chemokine type 7 receptor on the surface of a cell binding to one of it's physiological ligands, and ending with regulation of a downstream cellular process, e.g. transcription.	tmpzr1t_l9r_go_relaxed.owl	CCR7 signaling pathway|C-C chemokine receptor CCR7 signalling pathway					This term was created to show the binding of cytokines to multiple receptor types, and vice-versa. Known agonists of chemokine receptor type 7 (CCR7) are C-C chemokines CCL19 and CCL21. Consider instead annotating to one of the child terms 'CCL19-activated CCR7 signaling pathway ; GO:0038119' and/or 'CCL21-activated CCR7 signaling pathway ; GO:0038120'.		bf	2012-03-22T11:43:57Z					biological_process											owl:Class	
GO:0070098	biolink:NamedThing	chemokine-mediated signaling pathway	A series of molecular signals initiated by the binding of a chemokine to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.	tmpzr1t_l9r_go_relaxed.owl	chemokine-mediated signalling pathway													biological_process											owl:Class	
GO:0008652	biolink:NamedThing	cellular amino acid biosynthetic process	The chemical reactions and pathways resulting in the formation of amino acids, organic acids containing one or more amino substituents.	tmpzr1t_l9r_go_relaxed.owl	amino acid biosynthetic process|cellular amino acid anabolism|cellular amino acid biosynthesis|cellular amino acid synthesis|cellular amino acid formation				Wikipedia:Amino_acid_synthesis									biological_process											owl:Class	
GO:0046394	biolink:NamedThing	carboxylic acid biosynthetic process	The chemical reactions and pathways resulting in the formation of carboxylic acids, any organic acid containing one or more carboxyl (-COOH) groups.	tmpzr1t_l9r_go_relaxed.owl	carboxylic acid synthesis|carboxylic acid formation|carboxylic acid biosynthesis|carboxylic acid anabolism													biological_process											owl:Class	
GO:0010536	biolink:NamedThing	positive regulation of activation of Janus kinase activity	Any process that increases the frequency or rate of activation of JAK (Janus Activated Kinase) protein. The activation of JAK protein is the process of introducing a phosphate group to a tyrosine residue of a JAK (Janus Activated Kinase) protein, thereby activating it.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of tyrosine phosphorylation of JAK1 protein|positive regulation of activation of JAK protein|positive regulation of activation of JAK1 protein|positive regulation of activation of JAK1 kinase activity|positive regulation of tyrosine phosphorylation of JAK2 protein|positive regulation of activation of JAK2 kinase activity|positive regulation of tyrosine phosphorylation of JAK protein|positive regulation of activation of JAK2 protein											GO:0010537|GO:0010535		biological_process											owl:Class	
GO:0075138	biolink:NamedThing	response to host oxygen tension environment	Any process that results in a change in state or activity of the symbiont or its cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detecting oxygen tension in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	response of symbiont to host oxygen tension environment					Note that this term is used to annotate gene products of the symbiont.								biological_process											owl:Class	
GO:0075136	biolink:NamedThing	response to host	Any process that results in a change in state or activity of the symbiont or its cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	response of symbiont to host					Note that this term is used to annotate gene products of the symbiont.								biological_process											owl:Class	
GO:0090339	biolink:NamedThing	negative regulation of formin-nucleated actin cable assembly	Any process that decreases the rate, frequency, or extent of formin-nucleated actin cable assembly. Formin-nucleated actin cable assembly is the aggregation, arrangement and bonding together of a set of components to form a formin-nucleated actin cable. A formin-nucleated actin cable is an actin filament bundle that consists of short filaments organized into bundles of uniform polarity, and is nucleated by formins.	tmpzr1t_l9r_go_relaxed.owl								tb	2010-06-01T03:26:31Z					biological_process											owl:Class	
GO:1905661	biolink:NamedThing	regulation of telomerase RNA reverse transcriptase activity	Any process that modulates the frequency, rate or extent of telomerase RNA reverse transcriptase activity.	tmpzr1t_l9r_go_relaxed.owl	regulation of telomerase, catalyst							nc	2016-11-09T16:55:20Z					biological_process											owl:Class	
GO:0051972	biolink:NamedThing	regulation of telomerase activity	Any process that modulates the frequency, rate or extent of telomerase activity, the catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). Telomerases catalyze extension of the 3'- end of a DNA strand by one deoxynucleotide at a time using an internal RNA template that encodes the telomeric repeat sequence.	tmpzr1t_l9r_go_relaxed.owl	telomerase regulator													biological_process											owl:Class	
GO:0043799	biolink:NamedThing	glycine oxidase activity	Catalysis of the reactions: (1) glycine + H2O + O2 = glyoxylate + NH3 + hydrogen peroxide; (2) D-alanine + H2O + O2 = pyruvate + NH3 + hydrogen peroxide; (3) sarcosine + H2O + O2 = glyoxylate + methylamine + hydrogen peroxide; (4) N-ethylglycine + H2O + O2 = glyoxylate + ethylamine + hydrogen peroxide.	tmpzr1t_l9r_go_relaxed.owl	glycine:oxygen oxidoreductase (deaminating)				MetaCyc:1.4.3.19-RXN|MetaCyc:RXN-8672|EC:1.4.3.19|MetaCyc:RXN-8674|MetaCyc:RXN-8673									molecular_function											owl:Class	
GO:0016641	biolink:NamedThing	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH2 group acts as a hydrogen or electron donor and reduces an oxygen molecule.	tmpzr1t_l9r_go_relaxed.owl					EC:1.4.3.-									molecular_function											owl:Class	
GO:0075015	biolink:NamedThing	formation of infection structure	The formation of a symbiont structure that serves to infect its host organism. It includes physiological, developmental, and morphological changes of the symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	formation of host penetration structure|formation by symbiont of infection structure on or near host|formation of infection structure on or near host|formation of host infection structure	https://github.com/geneontology/go-ontology/issues/19014|https://github.com/geneontology/go-ontology/issues/20472				Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products of the symbiont involved in this process.								biological_process											owl:Class	
GO:0035371	biolink:NamedThing	microtubule plus-end	The growing (plus) end of a microtubule. In vitro, microtubules polymerize more quickly at the plus end than at the minus end. In vivo, microtubule growth occurs only at the plus end, and the plus end switches between periods of growth and shortening, a behavior known as dynamic instability.	tmpzr1t_l9r_go_relaxed.owl	growing microtubule plus end|microtubule plus end							bf	2010-03-11T10:55:00Z					cellular_component											owl:Class	
GO:1990752	biolink:NamedThing	microtubule end	Any end of a microtubule. Microtubule ends differ in that the so-called microtubule plus-end is the one that preferentially grows by polymerization, with respect to the minus-end.	tmpzr1t_l9r_go_relaxed.owl						This term should be used when it is not possible to distinguish between the two microtubule ends, e.g. during image annotation. Whenever possible, please annotate to one of the more specific children GO:0035371 'microtubule plus-end' or GO:0036449 'microtubule minus-end'.		pr	2015-05-25T12:50:31Z					cellular_component											owl:Class	
GO:1902158	biolink:NamedThing	positive regulation of response to G2 DNA damage checkpoint signaling	Any process that activates or increases the frequency, rate or extent of response to G2 DNA damage checkpoint signaling.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of G2/M transition DNA damage checkpoint effector process|up-regulation of response to signal involved in G2/M transition DNA damage checkpoint|up regulation of G2/M transition DNA damage checkpoint effector process|activation of response to G2 DNA damage checkpoint signaling|up regulation of response to signal involved in G2/M transition DNA damage checkpoint|upregulation of response to G2 DNA damage checkpoint signaling|up regulation of response to G2 DNA damage checkpoint signaling|upregulation of G2/M transition DNA damage checkpoint effector process|up-regulation of G2/M transition DNA damage checkpoint effector process|upregulation of response to signal involved in G2/M transition DNA damage checkpoint|positive regulation of response to signal involved in G2/M transition DNA damage checkpoint|up-regulation of response to G2 DNA damage checkpoint signaling|activation of response to signal involved in G2/M transition DNA damage checkpoint|activation of G2/M transition DNA damage checkpoint effector process							jl	2013-05-21T15:45:10Z					biological_process											owl:Class	
GO:1900833	biolink:NamedThing	D-leucine biosynthetic process	The chemical reactions and pathways resulting in the formation of D-leucine.	tmpzr1t_l9r_go_relaxed.owl	D-leucine anabolism|D-leucine biosynthesis|D-leucine formation|D-leucine synthesis							se	2012-06-06T09:37:47Z					biological_process											owl:Class	
GO:0009098	biolink:NamedThing	leucine biosynthetic process	The chemical reactions and pathways resulting in the formation of leucine, 2-amino-4-methylpentanoic acid.	tmpzr1t_l9r_go_relaxed.owl	leucine formation|leucine anabolism|leucine biosynthesis|leucine synthesis				MetaCyc:LEUSYN-PWY									biological_process											owl:Class	
GO:0035172	biolink:NamedThing	hemocyte proliferation	The multiplication or reproduction of hemocytes, resulting in the expansion of the cell population. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen.	tmpzr1t_l9r_go_relaxed.owl	arthropod blood cell proliferation													biological_process											owl:Class	
GO:0090280	biolink:NamedThing	positive regulation of calcium ion import	Any process that increases the rate, frequency, or extent of the directed movement of calcium ions into a cell or organelle.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of transmembrane calcium influx							tb	2010-02-08T05:11:20Z					biological_process											owl:Class	
GO:0051928	biolink:NamedThing	positive regulation of calcium ion transport	Any process that activates or increases the frequency, rate or extent of the directed movement of calcium ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	stimulation of calcium ion transport|positive regulation of calcium transport|up regulation of calcium ion transport|upregulation of calcium ion transport|up-regulation of calcium ion transport|activation of calcium ion transport													biological_process											owl:Class	
GO:0006101	biolink:NamedThing	citrate metabolic process	The chemical reactions and pathways involving citrate, 2-hydroxy-1,2,3-propanetricarboyxlate. Citrate is widely distributed in nature and is an important intermediate in the TCA cycle and the glyoxylate cycle.	tmpzr1t_l9r_go_relaxed.owl	citrate metabolism													biological_process											owl:Class	
GO:0032939	biolink:NamedThing	positive regulation of translation in response to oxidative stress	Any process that activates or increases the frequency, rate or extent of translation as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.	tmpzr1t_l9r_go_relaxed.owl	upregulation of translation in response to oxidative stress|stimulation of translation in response to oxidative stress|up regulation of translation in response to oxidative stress|activation of translation in response to oxidative stress|up-regulation of translation in response to oxidative stress													biological_process											owl:Class	
GO:0032056	biolink:NamedThing	positive regulation of translation in response to stress	Any process that activates or increases the frequency, rate or extent of translation as a result of a stimulus indicating the organism is under stress.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of translation in response to stress|up regulation of translation in response to stress|activation of translation in response to stress|upregulation of translation in response to stress|stimulation of translation in response to stress													biological_process											owl:Class	
GO:1902021	biolink:NamedThing	regulation of bacterial-type flagellum-dependent cell motility	Any process that modulates the frequency, rate or extent of bacterial-type flagellum-dependent cell motility.	tmpzr1t_l9r_go_relaxed.owl	regulation of bacterial-type flagellar cell motility|regulation of flagellin-based flagellar cell motility|regulation of bacterial-type flagellum cell motility							jl	2013-03-27T14:42:50Z					biological_process											owl:Class	
GO:2000145	biolink:NamedThing	regulation of cell motility	Any process that modulates the frequency, rate or extent of cell motility.	tmpzr1t_l9r_go_relaxed.owl	regulation of movement of a cell|regulation of cell movement|regulation of cell locomotion							mah	2010-10-01T09:41:21Z					biological_process											owl:Class	
GO:0009013	biolink:NamedThing	succinate-semialdehyde dehydrogenase [NAD(P)+] activity	Catalysis of the reaction: succinate semialdehyde + NAD(P)+ + H2O = succinate + NAD(P)H + H+.	tmpzr1t_l9r_go_relaxed.owl	succinate-semialdehyde:NAD(P)+ oxidoreductase activity|succinate semialdehyde dehydrogenase (nicotinamide adenine dinucleotide (phosphate))				UM-BBD_reactionID:r0371|EC:1.2.1.16|MetaCyc:SUCCSEMIALDDEHYDROG-RXN									molecular_function											owl:Class	
GO:0016620	biolink:NamedThing	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which an aldehyde or ketone (oxo) group acts as a hydrogen or electron donor and reduces NAD or NADP.	tmpzr1t_l9r_go_relaxed.owl					EC:1.2.1.-|Reactome:R-HSA-1222583									molecular_function											owl:Class	
GO:0090173	biolink:NamedThing	regulation of synaptonemal complex assembly	Any process that modulates the frequency, rate or extent of synaptonemal complex assembly. Synaptonemal complex assembly is the cell cycle process in which the synaptonemal complex, a structure that holds paired chromosomes together during prophase I of meiosis and that promotes genetic recombination, is formed.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-12-11T11:40:36Z					biological_process											owl:Class	
GO:0010564	biolink:NamedThing	regulation of cell cycle process	Any process that modulates a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0044195	biolink:NamedThing	nucleoplasmic reticulum	Long, dynamic tubular channels, formed by invagination of the nuclear envelope, that extend deep into the nucleoplasm. The channels have an underlying lamina and are implicated in functioning in signaling and transport.	tmpzr1t_l9r_go_relaxed.owl	nuclear channels							jl	2009-10-20T02:24:09Z					cellular_component											owl:Class	
GO:0060768	biolink:NamedThing	regulation of epithelial cell proliferation involved in prostate gland development	Any process that modulates the rate, frequency or extent of epithelial cell proliferation that contributes to the progression of the prostate gland over time.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-07-08T07:34:56Z					biological_process											owl:Class	
GO:1990186	biolink:NamedThing	regulation of lymphatic vessel size	Any process that modulates the size of lymphatic vessels.	tmpzr1t_l9r_go_relaxed.owl	regulation of collecting lymphatic vessel size							sl	2013-09-11T15:41:16Z					biological_process											owl:Class	
GO:1990183	biolink:NamedThing	lymphatic vascular process in circulatory system	A circulatory process that occurs at the level of the lymphatic vasculature.	tmpzr1t_l9r_go_relaxed.owl								sl	2013-09-10T22:26:40Z					biological_process											owl:Class	
GO:0080079	biolink:NamedThing	cellobiose glucosidase activity	Catalysis of the reaction: cellobiose + H2O = 2 D-glucose.	tmpzr1t_l9r_go_relaxed.owl	cellobiose glucohydrolase activity				MetaCyc:RXN-10773			dhl	2009-04-14T04:07:16Z					molecular_function											owl:Class	
GO:0008422	biolink:NamedThing	beta-glucosidase activity	Catalysis of the hydrolysis of terminal, non-reducing beta-D-glucose residues with release of beta-D-glucose.	tmpzr1t_l9r_go_relaxed.owl	beta-D-glucoside glucohydrolase activity|cellobiase activity|primeverosidase activity|emulsin|beta-1,6-glucosidase activity|beta-glucoside glucohydrolase activity|aryl-beta-glucosidase activity|cytokine beta-glucosidase activity|salicilinase activity|gentiobiase activity|limarase activity|amygdalase activity|gentobiase activity|arbutinase activity|amygdalinase|p-nitrophenyl beta-glucosidase activity|beta-D-glucosidase activity|elaterase activity				MetaCyc:3.2.1.21-RXN|EC:3.2.1.21							GO:0016983		molecular_function											owl:Class	
GO:0035066	biolink:NamedThing	positive regulation of histone acetylation	Any process that activates or increases the frequency, rate or extent of the addition of an acetyl group to a histone protein.	tmpzr1t_l9r_go_relaxed.owl	activation of histone acetylation|up-regulation of histone acetylation|upregulation of histone acetylation|stimulation of histone acetylation|up regulation of histone acetylation													biological_process											owl:Class	
GO:0045067	biolink:NamedThing	positive extrathymic T cell selection	The process of sparing extrathymically maturing T cells which react with self-MHC protein complexes with low affinity levels from apoptotic death.	tmpzr1t_l9r_go_relaxed.owl	positive extrathymic T-cell selection|positive extrathymic T-lymphocyte selection|positive extrathymic T lymphocyte selection													biological_process											owl:Class	
GO:0045062	biolink:NamedThing	extrathymic T cell selection	The process of T cell selection that occurs in extrathymic locations, often resulting T cells of distinct specificities from those selected in the thymus.	tmpzr1t_l9r_go_relaxed.owl	extrathymic T-lymphocyte selection|extrathymic T-cell selection|extrathymic T lymphocyte selection													biological_process											owl:Class	
GO:0035809	biolink:NamedThing	regulation of urine volume	Any process that modulates the amount of urine excreted from the body over a unit of time.	tmpzr1t_l9r_go_relaxed.owl	regulation of urinary volume|regulation of urine flow							bf	2011-04-20T01:17:38Z					biological_process											owl:Class	
GO:0003014	biolink:NamedThing	renal system process	A organ system process carried out by any of the organs or tissues of the renal system. The renal system maintains fluid balance, and contributes to electrolyte balance, acid/base balance, and disposal of nitrogenous waste products. In humans, the renal system comprises a pair of kidneys, a pair of ureters, urinary bladder, urethra, sphincter muscle and associated blood vessels; in other species, the renal system may comprise related structures (e.g., nephrocytes and malpighian tubules in Drosophila).	tmpzr1t_l9r_go_relaxed.owl	kidney system process|excretory system process													biological_process											owl:Class	
GO:1903399	biolink:NamedThing	positive regulation of m7G(5')pppN diphosphatase activity	Any process that activates or increases the frequency, rate or extent of m7G(5')pppN diphosphatase activity.	tmpzr1t_l9r_go_relaxed.owl	activation of m7G(5')pppN pyrophosphatase activity|up regulation of m7G(5')pppN pyrophosphatase activity|upregulation of decapase activity|up regulation of 7-methylguanosine-5'-triphospho-5'-polynucleotide 7-methylguanosine-5'-phosphohydrolase activity|up-regulation of M(7)G(5')pppN pyrophosphatase activity|activation of 7-methylguanosine-5'-triphospho-5'-polynucleotide 7-methylguanosine-5'-phosphohydrolase activity|up-regulation of 7-methylguanosine-5'-triphospho-5'-polynucleotide 7-methylguanosine-5'-phosphohydrolase activity|upregulation of m7G(5')pppN pyrophosphatase activity|up-regulation of m7G(5')pppN pyrophosphatase activity|upregulation of 7-methylguanosine-5'-triphospho-5'-polynucleotide 7-methylguanosine-5'-phosphohydrolase activity|activation of m7G(5')pppN diphosphatase activity|upregulation of M(7)G(5')pppN pyrophosphatase activity|upregulation of m7G(5')pppN diphosphatase activity|up-regulation of m7G(5')pppN diphosphatase activity|positive regulation of decapase activity|activation of M(7)G(5')pppN pyrophosphatase activity|positive regulation of m7G(5')pppN pyrophosphatase activity|activation of decapase activity|positive regulation of M(7)G(5')pppN pyrophosphatase activity|up regulation of M(7)G(5')pppN pyrophosphatase activity|up regulation of decapase activity|positive regulation of 7-methylguanosine-5'-triphospho-5'-polynucleotide 7-methylguanosine-5'-phosphohydrolase activity|up regulation of m7G(5')pppN diphosphatase activity|up-regulation of decapase activity							mah	2014-09-01T10:16:49Z					biological_process											owl:Class	
GO:1990559	biolink:NamedThing	mitochondrial coenzyme A transmembrane transport	The process in which coenzyme A is transported across a mitochondrial membrane, into or out of the mitochondrion.	tmpzr1t_l9r_go_relaxed.owl								vw	2014-11-19T12:58:26Z					biological_process											owl:Class	
GO:1990542	biolink:NamedThing	mitochondrial transmembrane transport	The process in which a solute is transported from one side of a membrane to the other into, out of or within a mitochondrion.	tmpzr1t_l9r_go_relaxed.owl								vw	2014-11-19T11:19:21Z					biological_process											owl:Class	
GO:0031942	biolink:NamedThing	i-AAA complex	Protease complex of the mitochondrial inner membrane whose catalytic residues lie on the intermembrane space side of the inner membrane; involved in mitochondrial protein turnover. Contains a subunit belonging to the AAA family of ATP-dependent metalloproteases.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0098800	biolink:NamedThing	inner mitochondrial membrane protein complex	Any protein complex that is part of the inner mitochondrial membrane.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0031846	biolink:NamedThing	neurotensin receptor binding	Binding to a neurotensin receptor.	tmpzr1t_l9r_go_relaxed.owl	neurotensin receptor ligand													molecular_function											owl:Class	
GO:0071855	biolink:NamedThing	neuropeptide receptor binding	Binding to a neuropeptide receptor.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-09-10T03:21:43Z					molecular_function											owl:Class	
GO:0034145	biolink:NamedThing	positive regulation of toll-like receptor 4 signaling pathway	Any process that activates or increases the frequency, rate, or extent of toll-like receptor 4 signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of toll-like receptor 4 signalling pathway|positive regulation of TLR4 signaling pathway													biological_process											owl:Class	
GO:0047125	biolink:NamedThing	delta1-piperideine-2-carboxylate reductase activity	Catalysis of the reaction: NADP+ + L-pipecolate = NADPH + delta1-piperideine-2-carboxylate.	tmpzr1t_l9r_go_relaxed.owl	delta 1-piperideine-2-carboxylate reductase activity|1,2-didehydropipecolic reductase activity|P2C reductase activity|D1-piperideine-2-carboxylate reductase activity|1,2-didehydropipecolate reductase activity|L-pipecolate:NADP+ 2-oxidoreductase activity				RHEA:12524|EC:1.5.1.21|MetaCyc:RXN-8166									molecular_function											owl:Class	
GO:0016646	biolink:NamedThing	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH group acts as a hydrogen or electron donor and reduces NAD or NADP.	tmpzr1t_l9r_go_relaxed.owl					EC:1.5.1.-									molecular_function											owl:Class	
GO:0045460	biolink:NamedThing	sterigmatocystin metabolic process	The chemical reactions and pathways involving sterigmatocystin, a carcinogenic mycotoxin produced in high yields by strains of the common molds.	tmpzr1t_l9r_go_relaxed.owl	sterigmatocystin metabolism													biological_process											owl:Class	
GO:0006725	biolink:NamedThing	cellular aromatic compound metabolic process	The chemical reactions and pathways involving aromatic compounds, any organic compound characterized by one or more planar rings, each of which contains conjugated double bonds and delocalized pi electrons, as carried out by individual cells.	tmpzr1t_l9r_go_relaxed.owl	aromatic hydrocarbon metabolic process|aromatic compound metabolism|aromatic hydrocarbon metabolism													biological_process											owl:Class	
GO:0000373	biolink:NamedThing	Group II intron splicing	The splicing of Group II introns. This occurs by a ribozymic mechanism where the intron sequence forms a distinct 3D structure, characteristic of Group II introns and containing splice site consensus sequences, that is involved in catalyzing the splicing reactions, though protein factors are also required in vivo. Splicing occurs by a series of two transesterification reactions (mechanistically similar to those for splicing of nuclear mRNAs) initiated by a bulged adenosine residue within the intron sequence as the initiating nucleophile. The intron is excised as a lariat.	tmpzr1t_l9r_go_relaxed.owl	mRNA splicing					Note that Group II introns are known to be found in a number of places: rRNA, mRNA, and tRNA in organelles of fungi, plants, and protists; and mRNA of bacteria.								biological_process											owl:Class	
GO:0000377	biolink:NamedThing	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile	Splicing of RNA via a series of two transesterification reactions with a bulged adenosine residue from the intron branch point as the initiating nucleophile. When the initial RNA for the splicing reaction is a single molecule (cis splicing), the excised intron is released in a lariat structure.	tmpzr1t_l9r_go_relaxed.owl	lariat RNA biosynthesis|lariat RNA formation													biological_process											owl:Class	
GO:0006769	biolink:NamedThing	nicotinamide metabolic process	The chemical reactions and pathways involving nicotinamide, pyridine-3-carboxamide, the amide of nicotinic acid. It is a member of the B complex of vitamins and occurs widely in living organisms.	tmpzr1t_l9r_go_relaxed.owl	nicotinamide metabolism|vitamin B3 metabolism|niacin metabolism|niacin metabolic process|vitamin B3 metabolic process				MetaCyc:PWY-5083									biological_process											owl:Class	
GO:0009820	biolink:NamedThing	alkaloid metabolic process	The chemical reactions and pathways involving alkaloids, nitrogen containing natural products which are not otherwise classified as peptides, nonprotein amino acids, amines, cyanogenic glycosides, glucosinolates, cofactors, phytohormones or primary metabolites (such as purine or pyrimidine bases).	tmpzr1t_l9r_go_relaxed.owl	alkaloid metabolism													biological_process											owl:Class	
GO:0030913	biolink:NamedThing	paranodal junction assembly	Formation of the junction between an axon and the glial cell that forms the myelin sheath. Paranodal junctions form at each paranode, i.e. at the ends of the unmyelinated nodes of Ranvier.	tmpzr1t_l9r_go_relaxed.owl	paranodal axoglial junction formation|paranodal junction formation|paranodal junction biosynthesis													biological_process											owl:Class	
GO:0010927	biolink:NamedThing	cellular component assembly involved in morphogenesis	The cellular component assembly that is part of the initial shaping of the component during its developmental progression.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0038120	biolink:NamedThing	CCL21-activated CCR7 signaling pathway	A series of molecular signals initiated by the binding of the C-C chemokine CCL21 to a C-C chemokine type 7 receptor (CCR7) on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.	tmpzr1t_l9r_go_relaxed.owl	CCL21-activated CCR7 signalling pathway							bf	2012-03-22T11:47:24Z					biological_process											owl:Class	
GO:0038116	biolink:NamedThing	chemokine (C-C motif) ligand 21 signaling pathway	A series of molecular signals initiated by the binding of the C-C chemokine CCL21 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.	tmpzr1t_l9r_go_relaxed.owl	CCL21-mediated signaling pathway|C-C chemokine receptor type 7 signaling pathway|chemokine (C-C motif) ligand 21 signalling pathway					The C-C chemokine CCL21 s a known agonist of the chemokine receptor type 7 (CCR7). Consider instead annotating to the child term 'CCL21-activated CCR7 signaling pathway ; GO:0038120'.		bf	2012-03-22T11:30:47Z					biological_process											owl:Class	
GO:0046121	biolink:NamedThing	deoxyribonucleoside catabolic process	The chemical reactions and pathways resulting in the breakdown of any one of a family of organic molecules consisting of a purine or pyrimidine base covalently bonded to a sugar deoxyribose (a deoxyribonucleoside).	tmpzr1t_l9r_go_relaxed.owl	deoxyribonucleoside degradation|deoxyribonucleoside catabolism|deoxyribonucleoside breakdown													biological_process											owl:Class	
GO:0009120	biolink:NamedThing	deoxyribonucleoside metabolic process	The chemical reactions and pathways involving any one of a family of organic molecules consisting of a purine or pyrimidine base covalently bonded to a sugar deoxyribose (a deoxyribonucleoside).	tmpzr1t_l9r_go_relaxed.owl	deoxyribonucleoside metabolism													biological_process											owl:Class	
GO:0015941	biolink:NamedThing	pantothenate catabolic process	The chemical reactions and pathways resulting in the breakdown of pantothenate, the anion of pantothenic acid. It is a B complex vitamin that is a constituent of coenzyme A and is distributed ubiquitously in foods.	tmpzr1t_l9r_go_relaxed.owl	vitamin B5 catabolic process|pantothenate catabolism|pantothenate breakdown|pantothenate degradation|vitamin B5 catabolism													biological_process											owl:Class	
GO:1903466	biolink:NamedThing	regulation of mitotic DNA replication initiation	Any process that modulates the frequency, rate or extent of DNA replication initiation involved in mitotic DNA replication.	tmpzr1t_l9r_go_relaxed.owl	regulation of DNA replication initiation involved in mitotic cell cycle DNA replication							vw	2014-09-23T13:38:49Z					biological_process											owl:Class	
GO:1903463	biolink:NamedThing	regulation of mitotic cell cycle DNA replication	Any process that modulates the frequency, rate or extent of mitotic cell cycle DNA replication.	tmpzr1t_l9r_go_relaxed.owl	regulation of DNA replication involved in S phase involved in mitotic cell cycle|regulation of DNA replication involved in S-phase involved in mitotic cell cycle|regulation of mitotic nuclear cell cycle DNA replication|regulation of DNA replication during S phase involved in mitotic cell cycle|regulation of nuclear cell cycle DNA replication involved in mitotic cell cycle							vw	2014-09-23T13:38:25Z					biological_process											owl:Class	
GO:1905876	biolink:NamedThing	positive regulation of postsynaptic density organization	Any process that activates or increases the frequency, rate or extent of postsynaptic density organization.	tmpzr1t_l9r_go_relaxed.owl	up regulation of postsynaptic density organisation|positive regulation of post synaptic density organization|activation of PSD organization|up regulation of post-synaptic density organization|activation of postsynaptic density organisation|activation of post synaptic density organization|up-regulation of postsynaptic density organisation|up-regulation of postsynaptic density organization|up regulation of post synaptic density organization|up-regulation of post-synaptic density organization|upregulation of post synaptic density organization|upregulation of postsynaptic density organization|activation of postsynaptic density organization|positive regulation of PSD organization|upregulation of PSD organization|up-regulation of PSD organization|up regulation of postsynaptic density organization|up regulation of PSD organization|activation of post-synaptic density organization|positive regulation of post-synaptic density organization|up-regulation of post synaptic density organization|upregulation of post-synaptic density organization|positive regulation of postsynaptic density organisation|upregulation of postsynaptic density organisation							sl	2017-01-27T19:53:50Z					biological_process											owl:Class	
GO:0006937	biolink:NamedThing	regulation of muscle contraction	Any process that modulates the frequency, rate or extent of muscle contraction.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0042919	biolink:NamedThing	benzoate transport	The directed movement of benzoate, the anion of benzoic acid (benzenecarboxylic acid) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0015849	biolink:NamedThing	organic acid transport	The directed movement of organic acids, any acidic compound containing carbon in covalent linkage, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0047463	biolink:NamedThing	2-aminohexano-6-lactam racemase activity	Catalysis of the reaction: L-2-aminohexano-6-lactam = D-2-aminohexano-6-lactam.	tmpzr1t_l9r_go_relaxed.owl	alpha-amino-epsilon-caprolactam racemase activity|2-amino-hexano-6-lactam racemase activity				RHEA:14813|EC:5.1.1.15|KEGG_REACTION:R04736|MetaCyc:5.1.1.15-RXN									molecular_function											owl:Class	
GO:0016855	biolink:NamedThing	racemase and epimerase activity, acting on amino acids and derivatives	Catalysis of a reaction that alters the configuration of one or more chiral centers in an amino acid.	tmpzr1t_l9r_go_relaxed.owl					EC:5.1.1.-									molecular_function											owl:Class	
GO:0044731	biolink:NamedThing	Ost-alpha/Ost-beta complex	A heterodimeric protein complex composed of Ost-alpha/SLC51A and Ost-beta/SLC51B subunits and involved in bile acid transport activity.	tmpzr1t_l9r_go_relaxed.owl	(Ost)2 complex|Ost alpha-Ost beta complex|SLC51 complex							jl	2012-11-06T13:42:06Z					cellular_component											owl:Class	
GO:0098797	biolink:NamedThing	plasma membrane protein complex	Any protein complex that is part of the plasma membrane.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:1900492	biolink:NamedThing	negative regulation of [4Fe-4S] cluster assembly	Any process that stops, prevents or reduces the frequency, rate or extent of [4Fe-4S] cluster assembly.	tmpzr1t_l9r_go_relaxed.owl	downregulation of 4Fe-4S cluster assembly|down regulation of [4Fe-4S] cluster assembly|inhibition of 4Fe-4S cluster assembly|downregulation of [4Fe-4S] cluster biosynthetic process|inhibition of [4Fe-4S] cluster biosynthetic process|down-regulation of [4Fe-4S] cluster assembly|down regulation of [4Fe-4S] cluster biosynthetic process|negative regulation of [4Fe-4S] cluster biosynthetic process|inhibition of [4Fe-4S] cluster assembly|negative regulation of 4Fe-4S cluster assembly|down-regulation of 4Fe-4S cluster assembly|down regulation of 4Fe-4S cluster assembly|down-regulation of [4Fe-4S] cluster biosynthetic process|downregulation of [4Fe-4S] cluster assembly							tt	2012-05-02T03:49:00Z					biological_process											owl:Class	
GO:1903330	biolink:NamedThing	negative regulation of iron-sulfur cluster assembly	Any process that stops, prevents or reduces the frequency, rate or extent of iron-sulfur cluster assembly.	tmpzr1t_l9r_go_relaxed.owl	downregulation of iron-sulfur cluster assembly|down regulation of iron-sulphur cluster assembly|inhibition of iron-sulphur cluster assembly|inhibition of iron-sulfur cluster biosynthesis|down regulation of iron-sulfur cluster assembly|down regulation of iron-sulfur cluster biosynthesis|downregulation of iron-sulphur cluster assembly|negative regulation of iron-sulfur cluster biosynthesis|down-regulation of iron-sulfur cluster biosynthesis|inhibition of iron-sulfur cluster assembly|down-regulation of iron-sulfur cluster assembly|downregulation of iron-sulfur cluster biosynthesis|down-regulation of iron-sulphur cluster assembly|negative regulation of iron-sulphur cluster assembly							vw	2014-08-18T13:12:50Z					biological_process											owl:Class	
GO:0016165	biolink:NamedThing	linoleate 13S-lipoxygenase activity	Catalysis of the reaction: linoleate + O2 = (9Z,11E)-(13S)-13-hydroperoxyoctadeca-9,11-dienoate.	tmpzr1t_l9r_go_relaxed.owl	lionoleate:O2 oxidoreductase activity|fat oxidase activity|lipoxygenase activity|carotene oxidase activity|linoleate:oxygen 13-oxidoreductase activity|lipoperoxidase activity|lipoxidase activity|lipoxydase activity				RHEA:22780|EC:1.13.11.12|MetaCyc:LIPOXYGENASE-RXN									molecular_function											owl:Class	
GO:0019299	biolink:NamedThing	rhamnose metabolic process	The chemical reactions and pathways involving rhamnose, the hexose 6-deoxy-L-mannose. Rhamnose occurs commonly as a compound of plant glycosides, in polysaccharides of gums and mucilages, and in bacterial polysaccharides. It is also a component of some plant cell wall polysaccharides and frequently acts as the sugar components of flavonoids.	tmpzr1t_l9r_go_relaxed.owl	rhamnose metabolism													biological_process											owl:Class	
GO:0019318	biolink:NamedThing	hexose metabolic process	The chemical reactions and pathways involving a hexose, any monosaccharide with a chain of six carbon atoms in the molecule.	tmpzr1t_l9r_go_relaxed.owl	hexose metabolism													biological_process											owl:Class	
GO:0005178	biolink:NamedThing	integrin binding	Binding to an integrin.	tmpzr1t_l9r_go_relaxed.owl	integrin ligand													molecular_function											owl:Class	
GO:0050839	biolink:NamedThing	cell adhesion molecule binding	Binding to a cell adhesion molecule.	tmpzr1t_l9r_go_relaxed.owl	CAM binding|cell adhesion receptor activity|cell adhesion molecule activity|adhesive extracellular matrix constituent													molecular_function											owl:Class	
GO:0090440	biolink:NamedThing	abscisic acid transmembrane transporter activity	Enables the transfer of abscisic acid from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	abscisic acid transporter activity							tb	2012-08-20T14:29:42Z					molecular_function											owl:Class	
GO:0015665	biolink:NamedThing	alcohol transmembrane transporter activity	Enables the transfer of an alcohol from one side of a membrane to the other. An alcohol is any carbon compound that contains a hydroxyl group.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0010900	biolink:NamedThing	negative regulation of phosphatidylcholine catabolic process	Any process that decreases the rate, frequency or extent of phosphatidylcholine catabolism. Phosphatidylcholine catabolic processes are the chemical reactions and pathways resulting in the breakdown of phosphatidylcholines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of choline.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0150174	biolink:NamedThing	negative regulation of phosphatidylcholine metabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of phosphatidylcholine metabolic process.	tmpzr1t_l9r_go_relaxed.owl								bc	2020-01-21T14:03:53Z					biological_process											owl:Class	
GO:2000849	biolink:NamedThing	regulation of glucocorticoid secretion	Any process that modulates the frequency, rate or extent of glucocorticoid secretion.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-07-26T08:44:43Z					biological_process											owl:Class	
GO:2000846	biolink:NamedThing	regulation of corticosteroid hormone secretion	Any process that modulates the frequency, rate or extent of corticosteroid hormone secretion.	tmpzr1t_l9r_go_relaxed.owl	regulation of corticosteroid secretion							bf	2011-07-26T08:43:38Z					biological_process											owl:Class	
GO:0033050	biolink:NamedThing	clavulanic acid biosynthetic process	The chemical reactions and pathways resulting in the formation of clavulanic acid, (2R,3Z,5R)-3-(2-hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo[3.2.0]heptane-2-carboxylic acid.	tmpzr1t_l9r_go_relaxed.owl	clavulanic acid anabolism|clavulanic acid formation|clavulanic acid synthesis|clavulanic acid biosynthesis				Wikipedia:Clavulanic_acid									biological_process											owl:Class	
GO:0050714	biolink:NamedThing	positive regulation of protein secretion	Any process that activates or increases the frequency, rate or extent of the controlled release of a protein from a cell.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of protein secretion|up regulation of protein secretion|activation of protein secretion|upregulation of protein secretion|stimulation of protein secretion													biological_process											owl:Class	
GO:1903532	biolink:NamedThing	positive regulation of secretion by cell	Any process that activates or increases the frequency, rate or extent of secretion by cell.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of cellular secretion|up-regulation of cellular secretion|up regulation of cellular secretion|activation of secretion by cell|upregulation of secretion by cell|up-regulation of secretion by cell|activation of cellular secretion|up regulation of secretion by cell|upregulation of cellular secretion							pm	2014-10-08T13:25:17Z					biological_process											owl:Class	
GO:1905042	biolink:NamedThing	negative regulation of epithelium regeneration	Any process that stops, prevents or reduces the frequency, rate or extent of epithelium regeneration.	tmpzr1t_l9r_go_relaxed.owl	inhibition of epithelium regeneration|down-regulation of regeneration of epithelium|downregulation of epithelium regeneration|down regulation of regeneration of epithelium|down-regulation of epithelium regeneration|down regulation of epithelium regeneration|negative regulation of regeneration of epithelium|downregulation of regeneration of epithelium|inhibition of regeneration of epithelium							rph	2016-03-11T10:59:03Z					biological_process											owl:Class	
GO:1905041	biolink:NamedThing	regulation of epithelium regeneration	Any process that modulates the frequency, rate or extent of epithelium regeneration.	tmpzr1t_l9r_go_relaxed.owl	regulation of regeneration of epithelium							rph	2016-03-11T10:58:53Z					biological_process											owl:Class	
GO:0016830	biolink:NamedThing	carbon-carbon lyase activity	Catalysis of the cleavage of C-C bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond.	tmpzr1t_l9r_go_relaxed.owl	other carbon-carbon lyase activity				EC:4.1.-.-|Reactome:R-HSA-389611									molecular_function											owl:Class	
GO:1900650	biolink:NamedThing	negative regulation of dehydroaustinol biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of dehydroaustinol biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	downregulation of dehydroaustinol anabolism|negative regulation of dehydroaustinol formation|down regulation of dehydroaustinol biosynthesis|down-regulation of dehydroaustinol synthesis|negative regulation of dehydroaustinol biosynthesis|down regulation of dehydroaustinol formation|inhibition of dehydroaustinol formation|down-regulation of dehydroaustinol biosynthetic process|inhibition of dehydroaustinol biosynthetic process|negative regulation of dehydroaustinol anabolism|downregulation of dehydroaustinol biosynthesis|downregulation of dehydroaustinol biosynthetic process|down-regulation of dehydroaustinol formation|down regulation of dehydroaustinol anabolism|inhibition of dehydroaustinol synthesis|downregulation of dehydroaustinol formation|down-regulation of dehydroaustinol anabolism|downregulation of dehydroaustinol synthesis|down regulation of dehydroaustinol biosynthetic process|negative regulation of dehydroaustinol synthesis|inhibition of dehydroaustinol anabolism|down-regulation of dehydroaustinol biosynthesis|inhibition of dehydroaustinol biosynthesis|down regulation of dehydroaustinol synthesis							di	2012-05-22T04:06:22Z					biological_process											owl:Class	
GO:0002705	biolink:NamedThing	positive regulation of leukocyte mediated immunity	Any process that activates or increases the frequency, rate, or extent of leukocyte mediated immunity.	tmpzr1t_l9r_go_relaxed.owl	stimulation of leukocyte mediated immunity|up-regulation of leukocyte mediated immunity|up regulation of leukocyte mediated immunity|positive regulation of immune cell mediated immunity|positive regulation of leucocyte mediated immunity|upregulation of leukocyte mediated immunity|activation of leukocyte mediated immunity													biological_process											owl:Class	
GO:0002703	biolink:NamedThing	regulation of leukocyte mediated immunity	Any process that modulates the frequency, rate, or extent of leukocyte mediated immunity.	tmpzr1t_l9r_go_relaxed.owl	regulation of immune cell mediated immunity|regulation of leucocyte mediated immunity													biological_process											owl:Class	
GO:0035776	biolink:NamedThing	pronephric proximal tubule development	The progression of the pronephric proximal tubule over time, from its formation to the mature structure. A pronephric nephron tubule is an epithelial tube that is part of the pronephros.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-04-04T11:02:54Z					biological_process											owl:Class	
GO:0039020	biolink:NamedThing	pronephric nephron tubule development	The process whose specific outcome is the progression of a pronephric nephron tubule over time, from its formation to the mature structure. The pronephric nephron tubule is an epithelial tube that is part of the pronephric nephron and connects the filtration unit (glomerulus or glomus) of the pronephros to the pronephric duct.	tmpzr1t_l9r_go_relaxed.owl								bf	2010-07-02T10:11:36Z					biological_process											owl:Class	
GO:0006598	biolink:NamedThing	polyamine catabolic process	The chemical reactions and pathways resulting in the breakdown of polyamines, any organic compound containing two or more amino groups.	tmpzr1t_l9r_go_relaxed.owl	polyamine degradation|polyamine breakdown|polyamine catabolism													biological_process											owl:Class	
GO:0006595	biolink:NamedThing	polyamine metabolic process	The chemical reactions and pathways involving polyamines, any organic compound containing two or more amino groups.	tmpzr1t_l9r_go_relaxed.owl	polyamine metabolism													biological_process											owl:Class	
GO:0106114	biolink:NamedThing	regulation of mitotic cohesin dsDNA (leading strand) loading	Any process that modulates the frequency, rate or extent of mitotic cohesin dsDNA (leading strand) loading.	tmpzr1t_l9r_go_relaxed.owl								hjd	2018-04-18T14:48:13Z					biological_process											owl:Class	
GO:0002722	biolink:NamedThing	negative regulation of B cell cytokine production	Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell cytokine production.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of B-lymphocyte cytokine production|down regulation of B cell cytokine production|negative regulation of B-cell cytokine production|negative regulation of B lymphocyte cytokine production|down-regulation of B cell cytokine production|downregulation of B cell cytokine production|inhibition of B cell cytokine production													biological_process											owl:Class	
GO:0010116	biolink:NamedThing	positive regulation of abscisic acid biosynthetic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of abscisic acid.	tmpzr1t_l9r_go_relaxed.owl	activation of abscisic acid biosynthetic process|positive regulation of abscisic acid biosynthesis|up-regulation of abscisic acid biosynthetic process|positive regulation of abscisic acid formation|positive regulation of abscisic acid anabolism|positive regulation of abscisic acid synthesis|stimulation of abscisic acid biosynthetic process|upregulation of abscisic acid biosynthetic process|up regulation of abscisic acid biosynthetic process													biological_process											owl:Class	
GO:0032892	biolink:NamedThing	positive regulation of organic acid transport	Any process that activates or increases the frequency, rate or extent of the directed movement of organic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	stimulation of organic acid transport|upregulation of organic acid transport|up regulation of organic acid transport|up-regulation of organic acid transport|activation of organic acid transport													biological_process											owl:Class	
GO:0032890	biolink:NamedThing	regulation of organic acid transport	Any process that modulates the frequency, rate or extent of the directed movement of organic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1905735	biolink:NamedThing	regulation of L-proline import across plasma membrane	Any process that modulates the frequency, rate or extent of L-proline import across plasma membrane.	tmpzr1t_l9r_go_relaxed.owl								vw	2016-12-04T20:42:16Z					biological_process											owl:Class	
GO:0036152	biolink:NamedThing	phosphatidylethanolamine acyl-chain remodeling	Remodeling the acyl chains of phosphatidylethanolamine, through sequential deacylation and re-acylation reactions, to generate phosphatidylethanolamine containing different types of fatty acid acyl chains.	tmpzr1t_l9r_go_relaxed.owl								bf	2012-03-14T02:09:00Z					biological_process											owl:Class	
GO:0046470	biolink:NamedThing	phosphatidylcholine metabolic process	The chemical reactions and pathways involving phosphatidylcholines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of choline. They are important constituents of cell membranes.	tmpzr1t_l9r_go_relaxed.owl	phosphatidylcholine metabolism													biological_process											owl:Class	
GO:0035343	biolink:NamedThing	negative regulation of inosine transport	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of inosine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of hypoxanthine riboside transport							bf	2010-03-04T10:06:07Z					biological_process											owl:Class	
GO:0046346	biolink:NamedThing	mannosamine catabolic process	The chemical reactions and pathways resulting in the breakdown of mannosomine, 2-amino-2-deoxymannose; the D-isomer is a constituent of neuraminic acids as well as mucolipids and mucoproteins.	tmpzr1t_l9r_go_relaxed.owl	mannosamine catabolism|mannosamine breakdown|mannosamine degradation													biological_process											owl:Class	
GO:0046348	biolink:NamedThing	amino sugar catabolic process	The chemical reactions and pathways resulting in the breakdown of any amino sugar, sugars containing an amino group in place of a hydroxyl group.	tmpzr1t_l9r_go_relaxed.owl	amino sugar catabolism|amino sugar degradation|aminosaccharide catabolism|aminosaccharide catabolic process|amino sugar breakdown													biological_process											owl:Class	
GO:0033787	biolink:NamedThing	cyanocobalamin reductase (cyanide-eliminating) activity	Catalysis of the reaction: cob(I)alamin + hydrogen cyanide + NADP(+) = cyanocob(III)alamin + H(+) + NADPH.	tmpzr1t_l9r_go_relaxed.owl	cyanocobalamin reductase (NADPH; CN-eliminating) activity|cob(I)alamin, cyanide:NADP+ oxidoreductase activity|cyanocobalamin reductase (NADPH, cyanide-eliminating) activity|NADPH2:cyanocob(III)alamin oxidoreductase (cyanide-eliminating) activity|NADPH:cyanocob(III)alamin oxidoreductase (cyanide-eliminating) activity|cyanocobalamin reductase activity				EC:1.16.1.6|RHEA:16113|MetaCyc:1.6.99.12-RXN|Reactome:R-HSA-3149519|KEGG_REACTION:R02999	Formerly EC:1.6.99.12.								molecular_function											owl:Class	
GO:0016723	biolink:NamedThing	oxidoreductase activity, acting on metal ions, NAD or NADP as acceptor	Catalysis of an oxidation-reduction in which the metal ion is reduced and NAD+ or NADP+ acts as an electron acceptor.	tmpzr1t_l9r_go_relaxed.owl	oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor|oxidoreductase activity, reducing metal ions, NAD or NADP as acceptor	https://github.com/geneontology/go-ontology/issues/20675			EC:1.16.1.-|Reactome:R-HSA-917811									molecular_function											owl:Class	
GO:0035539	biolink:NamedThing	8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity	Catalysis of the reaction: 8-oxo-7,8-dihydrodeoxyguanosine-triphosphate (8-oxo-dGTP) + H2O = 8-oxo-7,8-dihydrodeoxyguanosine phosphate (8-oxo-dGMP) + diphosphate. 8-oxo-dGTP is the oxidised form of the free guanine nucleotide and can act as a potent mutagenic substrate for DNA synthesis causing transversion mutations. 8-oxo-dGTPase hydrolyses 8-oxo-dGTP to its monophosphate form to prevent the misincorporation of 8-oxo-dGTP into cellular DNA.	tmpzr1t_l9r_go_relaxed.owl	8-oxo-7,8-dihydrodeoxyguanosine triphosphatase activity|8-oxo-dGTP pyrophosphohydrolase activity|8-oxo-7,8-dihydro-2'-deoxyguanosine 5'-triphosphate pyrophosphohydrolase activity|8-oxo-dGTPase activity|8-oxo-7,8-dihydro-deoxyguanosine triphosphate pyrophosphatase activity				RHEA:31575|Reactome:R-HSA-2395869|Reactome:R-HSA-2395849|EC:3.6.1.55			bf	2010-05-07T10:54:19Z					molecular_function											owl:Class	
GO:0047429	biolink:NamedThing	nucleoside-triphosphate diphosphatase activity	Catalysis of the reaction: H2O + a nucleoside triphosphate = diphosphate + a nucleotide.	tmpzr1t_l9r_go_relaxed.owl	nucleoside-triphosphate pyrophosphatase activity|nucleoside-triphosphate diphosphohydrolase activity				MetaCyc:3.6.1.19-RXN|EC:3.6.1.9									molecular_function											owl:Class	
GO:0140052	biolink:NamedThing	cellular response to oxidised low-density lipoprotein particle stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxidized lipoprotein particle stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to oxidised LDL particle stimulus|cellular response to oxidized LDL particle stimulus|cellular response to ox-LDL particle stimulus|cellular response to oxLDL particle stimulus|cellular response to oxidized low-density lipoprotein particle stimulus							pg	2017-06-26T09:40:00Z					biological_process											owl:Class	
GO:0055094	biolink:NamedThing	response to lipoprotein particle	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipoprotein particle stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to lipoprotein particle stimulus													biological_process											owl:Class	
GO:0016799	biolink:NamedThing	hydrolase activity, hydrolyzing N-glycosyl compounds	Catalysis of the hydrolysis of any N-glycosyl bond.	tmpzr1t_l9r_go_relaxed.owl					EC:3.2.2.-									molecular_function											owl:Class	
GO:0016798	biolink:NamedThing	hydrolase activity, acting on glycosyl bonds	Catalysis of the hydrolysis of any glycosyl bond.	tmpzr1t_l9r_go_relaxed.owl	glycosidase activity|glycosylase|N-glycosylase				Reactome:R-HSA-2065233|Reactome:R-HSA-1793176|EC:3.2.-.-									molecular_function											owl:Class	
GO:0042684	biolink:NamedThing	cardioblast cell fate commitment	The process in which a cell becomes committed to becoming a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0060911	biolink:NamedThing	cardiac cell fate commitment	The commitment of cells to specific cardiac cell fates and their capacity to differentiate into cardiac cells. Cardiac cells are cells that comprise the organ which pumps blood through the circulatory system.	tmpzr1t_l9r_go_relaxed.owl	cardiocyte cell fate commitment							dph	2009-09-17T08:47:00Z					biological_process											owl:Class	
GO:0008568	biolink:NamedThing	microtubule-severing ATPase activity	Catalysis of the reaction: ATP + H2O = ADP + phosphate. Catalysis of the severing of a microtubule at a specific spot along its length, coupled to the hydrolysis of ATP.	tmpzr1t_l9r_go_relaxed.owl	katanin activity|ATP phosphohydrolase (tubulin-dimerizing)				EC:5.6.1.1|MetaCyc:3.6.4.3-RXN|Reactome:R-HSA-9668419	See also the cellular component term 'katanin complex ; GO:0008352'.								molecular_function											owl:Class	
GO:0140096	biolink:NamedThing	catalytic activity, acting on a protein	Catalytic activity that acts to modify a protein.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/14225						pg	2017-09-14T10:32:59Z					molecular_function											owl:Class	
GO:0018912	biolink:NamedThing	1,4-dichlorobenzene metabolic process	The chemical reactions and pathways involving 1,4-dichlorobenzene (p-dichlorobenzene or paramoth), a derivative of benzene with two chlorine atoms attached at opposite positions on the ring. It forms white crystals at room temperature and is used as an insecticidal fumigant, particularly in mothballs.	tmpzr1t_l9r_go_relaxed.owl	1,4-dichlorobenzene metabolism				UM-BBD_pathwayID:dcz									biological_process											owl:Class	
GO:0042537	biolink:NamedThing	benzene-containing compound metabolic process	The chemical reactions and pathways involving benzene, C6H6, a volatile, very inflammable liquid, contained in the naphtha produced by the destructive distillation of coal, from which it is separated by fractional distillation, or any of its derivatives.	tmpzr1t_l9r_go_relaxed.owl	benzene and derivative metabolism|benzene and derivative metabolic process|benzene-containing compound metabolism													biological_process											owl:Class	
GO:0090298	biolink:NamedThing	negative regulation of mitochondrial DNA replication	Any process that decreases the rate, frequency or extent of the process in which new strands of DNA are synthesized in the mitochondrion.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of mitochondrial DNA synthesis							tb	2010-03-12T03:58:25Z					biological_process											owl:Class	
GO:2000104	biolink:NamedThing	negative regulation of DNA-dependent DNA replication	Any process that stops, prevents, or reduces the frequency, rate or extent of DNA-dependent DNA replication.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-09-15T01:37:05Z					biological_process											owl:Class	
GO:0098759	biolink:NamedThing	cellular response to interleukin-8	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-8 stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to IL-8													biological_process											owl:Class	
GO:0071345	biolink:NamedThing	cellular response to cytokine stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytokine stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-12-11T02:41:12Z					biological_process											owl:Class	
GO:0061264	biolink:NamedThing	mesonephric glomerular mesangial cell fate commitment	The process in which the developmental fate of a cell becomes restricted such that it will develop into a mesonephric glomerular mesangial cell.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-08-30T02:59:11Z					biological_process											owl:Class	
GO:0072152	biolink:NamedThing	glomerular mesangial cell fate commitment	The process in which the developmental fate of a cell becomes restricted such that it will develop into a glomerular mesangial cell.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-02-24T02:14:58Z					biological_process											owl:Class	
GO:0071394	biolink:NamedThing	cellular response to testosterone stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a testosterone stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-12-11T04:11:29Z					biological_process											owl:Class	
GO:0042457	biolink:NamedThing	ethylene catabolic process	The chemical reactions and pathways resulting in the breakdown of ethylene (C2-H4, ethene), a simple hydrocarbon gas that can function in plants as a growth regulator.	tmpzr1t_l9r_go_relaxed.owl	ethylene breakdown|ethene catabolism|ethene catabolic process|ethylene degradation|ethylene catabolism													biological_process											owl:Class	
GO:0009692	biolink:NamedThing	ethylene metabolic process	The chemical reactions and pathways involving ethylene (C2-H4, ethene), a simple hydrocarbon gas that can function in plants as a growth regulator.	tmpzr1t_l9r_go_relaxed.owl	ethene metabolic process|ethylene metabolism|ethene metabolism													biological_process											owl:Class	
GO:1902207	biolink:NamedThing	positive regulation of interleukin-2-mediated signaling pathway	Any process that activates or increases the frequency, rate or extent of interleukin-2-mediated signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of interleukin-2-mediated signalling pathway|upregulation of interleukin-2-mediated signaling pathway|up regulation of IL-2-mediated signaling pathway|up-regulation of interleukin-2-mediated signaling pathway|activation of IL-2-mediated signaling pathway|activation of interleukin-2-mediated signaling pathway|up regulation of interleukin-2-mediated signaling pathway|upregulation of IL-2-mediated signaling pathway|up-regulation of interleukin-2-mediated signalling pathway|activation of interleukin-2-mediated signalling pathway|upregulation of interleukin-2-mediated signalling pathway|positive regulation of IL-2-mediated signaling pathway|up regulation of interleukin-2-mediated signalling pathway|up-regulation of IL-2-mediated signaling pathway							lb	2013-06-11T07:34:50Z					biological_process											owl:Class	
GO:0042846	biolink:NamedThing	glycol catabolic process	The chemical reactions and pathways resulting in the breakdown of glycol, a diol in which the two hydroxy groups are on different carbon atoms, usually but not necessarily adjacent.	tmpzr1t_l9r_go_relaxed.owl	glycol degradation|glycol breakdown|glycol catabolism|dihydric alcohol catabolism|dihydric alcohol catabolic process													biological_process											owl:Class	
GO:0042844	biolink:NamedThing	glycol metabolic process	The chemical reactions and pathways involving glycol, a diol in which the two hydroxy groups are on different carbon atoms, usually but not necessarily adjacent.	tmpzr1t_l9r_go_relaxed.owl	dihydric alcohol metabolic process|dihydric alcohol metabolism|glycol metabolism													biological_process											owl:Class	
GO:2000553	biolink:NamedThing	positive regulation of T-helper 2 cell cytokine production	Any process that activates or increases the frequency, rate or extent of T-helper 2 cell cytokine production.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of Th2 cell cytokine production							ebc	2011-04-03T07:32:58Z					biological_process											owl:Class	
GO:0002726	biolink:NamedThing	positive regulation of T cell cytokine production	Any process that activates or increases the frequency, rate, or extent of T cell cytokine production.	tmpzr1t_l9r_go_relaxed.owl	activation of T cell cytokine production|stimulation of T cell cytokine production|positive regulation of T-cell cytokine production|up regulation of T cell cytokine production|upregulation of T cell cytokine production|positive regulation of T lymphocyte cytokine production|positive regulation of T-lymphocyte cytokine production|up-regulation of T cell cytokine production													biological_process											owl:Class	
GO:0005142	biolink:NamedThing	interleukin-11 receptor binding	Binding to an interleukin-11 receptor.	tmpzr1t_l9r_go_relaxed.owl	IL-11|interleukin-11 receptor ligand													molecular_function											owl:Class	
GO:0070851	biolink:NamedThing	growth factor receptor binding	Binding to a growth factor receptor.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-08-07T11:23:02Z					molecular_function											owl:Class	
GO:0010735	biolink:NamedThing	positive regulation of transcription via serum response element binding	Any process that increases the frequency, rate or extent of the specifically regulated synthesis of RNA from DNA encoding a specific set of genes as a result of a transcription factor interacting with a serum response element (SRE). A serum response element is a short sequence with dyad symmetry found in the promoters of some of the cellular immediate-early genes, regulated by serum.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0045944	biolink:NamedThing	positive regulation of transcription by RNA polymerase II	Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.	tmpzr1t_l9r_go_relaxed.owl	stimulation of global transcription from RNA polymerase II promoter|upregulation of transcription from RNA polymerase II promoter|stimulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|up-regulation of global transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter, global|activation of transcription from RNA polymerase II promoter|up-regulation of transcription from RNA polymerase II promoter|upregulation of global transcription from RNA polymerase II promoter|up regulation of global transcription from RNA polymerase II promoter|activation of global transcription from RNA polymerase II promoter|positive regulation of gene-specific transcription from RNA polymerase II promoter|up regulation of transcription from RNA polymerase II promoter|positive regulation of global transcription from Pol II promoter|positive regulation of transcription from Pol II promoter											GO:0010552|GO:0045817		biological_process											owl:Class	
GO:0060862	biolink:NamedThing	negative regulation of floral organ abscission	Any process that decreases the rate, frequency, or extent of floral organ abscission, the controlled shedding of floral organs.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-08-12T04:05:23Z					biological_process											owl:Class	
GO:0018243	biolink:NamedThing	protein O-linked glycosylation via threonine	The glycosylation of protein via the O3 atom of peptidyl-threonine, forming O3-glycosyl-L-threonine; the most common forms are N-acetylgalactosaminyl, mannosyl, and galactosyl threonine.	tmpzr1t_l9r_go_relaxed.owl	protein amino acid O-linked glycosylation via threonine				RESID:AA0155									biological_process											owl:Class	
GO:0006493	biolink:NamedThing	protein O-linked glycosylation	A protein glycosylation process in which a carbohydrate or carbohydrate derivative unit is added to a protein via the hydroxyl group of peptidyl-serine, peptidyl-threonine, peptidyl-hydroxylysine, or peptidyl-hydroxyproline, or via the phenol group of peptidyl-tyrosine, forming an O-glycan.	tmpzr1t_l9r_go_relaxed.owl	protein amino acid O-linked glycosylation				RESID:AA0157|RESID:AA0212|RESID:AA0153|RESID:AA0154|RESID:AA0155									biological_process											owl:Class	
GO:0015969	biolink:NamedThing	guanosine tetraphosphate metabolic process	The chemical reactions and pathways involving guanine tetraphosphate (5'-ppGpp-3'), a derivative of guanine riboside with four phosphates.	tmpzr1t_l9r_go_relaxed.owl	guanosine tetraphosphate (5'-ppGpp-3') metabolism|guanosine tetraphosphate metabolism|guanosine tetraphosphate (5'-ppGpp-3') metabolic process				MetaCyc:PPGPPMET-PWY									biological_process											owl:Class	
GO:0009150	biolink:NamedThing	purine ribonucleotide metabolic process	The chemical reactions and pathways involving a purine ribonucleotide, a compound consisting of ribonucleoside (a purine base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.	tmpzr1t_l9r_go_relaxed.owl	purine ribonucleotide metabolism													biological_process											owl:Class	
GO:1903358	biolink:NamedThing	regulation of Golgi organization	Any process that modulates the frequency, rate or extent of Golgi organization.	tmpzr1t_l9r_go_relaxed.owl	regulation of Golgi organisation|regulation of Golgi organization and biogenesis							als	2014-08-21T10:22:22Z					biological_process											owl:Class	
GO:0042323	biolink:NamedThing	negative regulation of circadian sleep/wake cycle, non-REM sleep	Any process that stops, prevents or reduces the duration or quality of non-rapid eye movement (NREM) sleep.	tmpzr1t_l9r_go_relaxed.owl	down regulation of circadian sleep/wake cycle, non-REM sleep|inhibition of circadian sleep/wake cycle, non-REM sleep|negative regulation of non-REM sleep|down-regulation of circadian sleep/wake cycle, non-REM sleep|downregulation of circadian sleep/wake cycle, non-REM sleep													biological_process											owl:Class	
GO:0036140	biolink:NamedThing	peptidyl-asparagine 3-dioxygenase activity	Catalysis of the reaction: peptidyl L-asparagine + 2-oxoglutarate + O2 = peptidyl 3-hydroxy-L-asparagine + succinate + CO2.	tmpzr1t_l9r_go_relaxed.owl								bf	2012-03-07T09:27:44Z					molecular_function											owl:Class	
GO:1901657	biolink:NamedThing	glycosyl compound metabolic process	The chemical reactions and pathways involving glycosyl compound.	tmpzr1t_l9r_go_relaxed.owl	glycosyl compound metabolism							pr	2012-11-20T14:24:07Z					biological_process											owl:Class	
GO:1901135	biolink:NamedThing	carbohydrate derivative metabolic process	The chemical reactions and pathways involving carbohydrate derivative.	tmpzr1t_l9r_go_relaxed.owl	carbohydrate derivative metabolism							bf	2012-07-12T04:05:09Z					biological_process											owl:Class	
GO:0002707	biolink:NamedThing	negative regulation of lymphocyte mediated immunity	Any process that stops, prevents, or reduces the frequency, rate, or extent of lymphocyte mediated immunity.	tmpzr1t_l9r_go_relaxed.owl	inhibition of lymphocyte mediated immunity|downregulation of lymphocyte mediated immunity|down regulation of lymphocyte mediated immunity|down-regulation of lymphocyte mediated immunity													biological_process											owl:Class	
GO:0002704	biolink:NamedThing	negative regulation of leukocyte mediated immunity	Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte mediated immunity.	tmpzr1t_l9r_go_relaxed.owl	inhibition of leukocyte mediated immunity|negative regulation of leucocyte mediated immunity|negative regulation of immune cell mediated immunity|downregulation of leukocyte mediated immunity|down regulation of leukocyte mediated immunity|down-regulation of leukocyte mediated immunity													biological_process											owl:Class	
GO:0150070	biolink:NamedThing	regulation of arginase activity	Any process that modulates the frequency, rate or extent of arginase activity.	tmpzr1t_l9r_go_relaxed.owl								bc	2018-07-25T09:17:30Z					biological_process											owl:Class	
GO:0060906	biolink:NamedThing	negative regulation of heterochromatin assembly by small RNA	Any process that decreases the frequency, rate or extent of heterochromatin assembly by small RNA.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of chromatin silencing by small RNA|negative regulation of RNAi-mediated heterochromatin assembly	https://github.com/geneontology/go-ontology/issues/19112						dph	2009-08-14T01:22:24Z					biological_process											owl:Class	
GO:0010964	biolink:NamedThing	regulation of heterochromatin assembly by small RNA	Any process that modulates the frequency, rate or extent of heterochromatin assembly by small RNA.	tmpzr1t_l9r_go_relaxed.owl	regulation of RNAi-mediated heterochromatin assembly|regulation of chromatin silencing by small RNA	https://github.com/geneontology/go-ontology/issues/19112						tb	2009-05-20T11:25:42Z					biological_process											owl:Class	
GO:0150077	biolink:NamedThing	regulation of neuroinflammatory response	Any process that modulates the frequency, rate or extent of neuroinflammatory response.	tmpzr1t_l9r_go_relaxed.owl								bc	2018-07-26T12:32:18Z					biological_process											owl:Class	
GO:0050727	biolink:NamedThing	regulation of inflammatory response	Any process that modulates the frequency, rate or extent of the inflammatory response, the immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0048000	biolink:NamedThing	isoflavone 3'-hydroxylase activity	Catalysis of the reaction: formononetin + NADPH + O2 = calycosin + NADP+ + H2O.	tmpzr1t_l9r_go_relaxed.owl	formononetin,NADPH:oxygen oxidoreductase (3'-hydroxylating)|isoflavone 3'-monooxygenase activity				RHEA:22960|EC:1.14.14.88|MetaCyc:RXN-3762									molecular_function											owl:Class	
GO:0099556	biolink:NamedThing	trans-synaptic signaling by carbon monoxide, modulating synaptic transmission	Cell-cell signaling between presynapse and postsynapse, via the release and reception of carbon monoxide molecules, that modulates the synaptic transmission properties of the synapse.	tmpzr1t_l9r_go_relaxed.owl						Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.								biological_process											owl:Class	
GO:0099554	biolink:NamedThing	trans-synaptic signaling by soluble gas, modulating synaptic transmission	Cell-cell signaling between presynapse and postsynapse, via the release and reception of gaseous molecules, that modulates the synaptic transmission properties of the synapse.	tmpzr1t_l9r_go_relaxed.owl						Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.								biological_process											owl:Class	
GO:0018798	biolink:NamedThing	gallate decarboxylase activity	Catalysis of the reaction: gallate + H(+) = CO(2) + pyrogallol.	tmpzr1t_l9r_go_relaxed.owl	gallate carboxy-lyase activity|gallic acid decarboxylase activity|gallate carboxy-lyase (pyrogallol-forming)				RHEA:12749|MetaCyc:GALLATE-DECARBOXYLASE-RXN|EC:4.1.1.59|UM-BBD_reactionID:r0005|KEGG_REACTION:R03247									molecular_function											owl:Class	
GO:0039602	biolink:NamedThing	suppression by virus of host transcription initiation from RNA polymerase II promoter	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of the assembly of the RNA polymerase II preinitiation complex (PIC) at an RNA polymerase II promoter region of a host DNA template.	tmpzr1t_l9r_go_relaxed.owl	inhibition of host transcription initiation by virus|suppression by virus of host DNA-dependent transcription, initiation				VZ:904			bf	2012-07-05T03:29:34Z			GO:0039601		biological_process											owl:Class	
GO:0039653	biolink:NamedThing	suppression by virus of host transcription	Any process in which a virus stops, prevents, or reduces the activity of host DNA-dependent transcription; the cellular synthesis of RNA on a template of DNA. Viral proteins can interfere with either host RNA polymerase or with transcription factors.	tmpzr1t_l9r_go_relaxed.owl	host transcription shutoff by virus|suppression by virus of host DNA-dependent transcription				VZ:1577			bf	2012-10-11T16:11:17Z					biological_process											owl:Class	
GO:0099175	biolink:NamedThing	regulation of postsynapse organization	Any process that modulates the physical form of a postsynapse.	tmpzr1t_l9r_go_relaxed.owl	regulation of postsynapse structure|regulation of postsynapse organisation|regulation of postsynapse organization and biogenesis													biological_process											owl:Class	
GO:0140667	biolink:NamedThing	regulation of oxytocin production	Any process that modulates the frequency, rate, or extent of production of oxytocin.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/21535						pg	2021-06-24T11:28:07Z					biological_process											owl:Class	
GO:2000199	biolink:NamedThing	positive regulation of ribonucleoprotein complex localization	Any process that activates or increases the frequency, rate or extent of ribonucleoprotein complex localization.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of establishment and maintenance of ribonucleoprotein complex localization|positive regulation of cellular ribonucleoprotein complex localization|positive regulation of ribonucleoprotein complex localisation|positive regulation of RNP localization							mah	2010-10-26T10:35:55Z					biological_process											owl:Class	
GO:2000197	biolink:NamedThing	regulation of ribonucleoprotein complex localization	Any process that modulates the frequency, rate or extent of ribonucleoprotein complex localization.	tmpzr1t_l9r_go_relaxed.owl	regulation of cellular ribonucleoprotein complex localization|regulation of RNP localization|regulation of ribonucleoprotein complex localisation|regulation of establishment and maintenance of ribonucleoprotein complex localization							mah	2010-10-26T10:35:48Z					biological_process											owl:Class	
GO:1900515	biolink:NamedThing	regulation of xylose catabolic process to ethanol	Any process that modulates the frequency, rate or extent of xylose catabolic process to ethanol.	tmpzr1t_l9r_go_relaxed.owl	regulation of xylose catabolism to ethanol							tt	2012-05-02T04:09:07Z					biological_process											owl:Class	
GO:0043469	biolink:NamedThing	regulation of D-xylose catabolic process	Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of xylose.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0046374	biolink:NamedThing	teichoic acid metabolic process	The chemical reactions and pathways involving teichoic acid, any polymer occurring in the cell wall, membrane or capsule of Gram-positive bacteria and containing chains of glycerol phosphate or ribitol phosphate residues.	tmpzr1t_l9r_go_relaxed.owl	teichoic acid metabolism													biological_process											owl:Class	
GO:0080145	biolink:NamedThing	cysteine homeostasis	Any process involved in the maintenance of an internal steady state of cysteine within an organism or cell.	tmpzr1t_l9r_go_relaxed.owl								dhl	2010-01-27T04:49:14Z					biological_process											owl:Class	
GO:0055080	biolink:NamedThing	cation homeostasis	Any process involved in the maintenance of an internal steady state of cations within an organism or cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0021905	biolink:NamedThing	forebrain-midbrain boundary formation	The process whose specific outcome is the creation of the forebrain-midbrain boundary.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0003415	biolink:NamedThing	chondrocyte hypertrophy	The growth of a chondrocyte, where growth contributes to the progression of the chondrocyte over time.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-12-22T08:48:44Z					biological_process											owl:Class	
GO:0048588	biolink:NamedThing	developmental cell growth	The growth of a cell, where growth contributes to the progression of the cell over time from one condition to another.	tmpzr1t_l9r_go_relaxed.owl	developmental growth of a unicellular organism													biological_process											owl:Class	
GO:0062126	biolink:NamedThing	fatty acid primary amide metabolic process	The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform primary fatty amides.	tmpzr1t_l9r_go_relaxed.owl	primary fatty amide metabolic process							dph	2019-05-30T18:23:02Z					biological_process											owl:Class	
GO:0010684	biolink:NamedThing	tricyclic triterpenoid catabolic process	The chemical reactions and pathways resulting in the breakdown of tricyclic triterpenoid compounds, terpenoids with six isoprene units and 3 rings.	tmpzr1t_l9r_go_relaxed.owl	tricyclic triterpenoid catabolism													biological_process											owl:Class	
GO:0018184	biolink:NamedThing	protein polyamination	The modification of a protein amino acid by polyamination.	tmpzr1t_l9r_go_relaxed.owl	protein amino acid polyamination													biological_process											owl:Class	
GO:0006464	biolink:NamedThing	cellular protein modification process	The covalent alteration of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications) occurring at the level of an individual cell. Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification).	tmpzr1t_l9r_go_relaxed.owl	protein tagging activity|process resulting in protein modification|protein modification process													biological_process											owl:Class	
GO:0032533	biolink:NamedThing	regulation of follicle cell microvillus length	A process that modulates the length of a microvillus on a follicle cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0008361	biolink:NamedThing	regulation of cell size	Any process that modulates the size of a cell.	tmpzr1t_l9r_go_relaxed.owl	cell size control													biological_process											owl:Class	
GO:0015464	biolink:NamedThing	acetylcholine receptor activity	Combining with acetylcholine and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl						For nicotinic acetylcholine receptors that act as ion channels, instead use 'acetylcholine-gated cation channel activity ; GO:0022848'.								molecular_function											owl:Class	
GO:0061130	biolink:NamedThing	pancreatic bud formation	The morphogenetic process in which the foregut region specified to become the pancreas forms a bud.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-05-17T09:33:40Z					biological_process											owl:Class	
GO:0048645	biolink:NamedThing	animal organ formation	The process pertaining to the initial formation of an animal organ from unspecified parts. The process begins with the specific processes that contribute to the appearance of the discrete structure, such as inductive events, and ends when the structural rudiment of the organ is recognizable, such as a condensation of mesenchymal cells into the organ rudiment. Organs are a natural part or structure in an animal or a plant, capable of performing some special action (termed its function), which is essential to the life or well-being of the whole. The heart and lungs are organs of animals, and the petal and leaf are organs of plants. In animals the organs are generally made up of several tissues, one of which usually predominates, and determines the principal function of the organ.	tmpzr1t_l9r_go_relaxed.owl	initiation of an animal organ primordium|animal organ primordium initiation													biological_process											owl:Class	
GO:1900452	biolink:NamedThing	regulation of long-term synaptic depression	Any process that modulates the frequency, rate or extent of long term synaptic depression.	tmpzr1t_l9r_go_relaxed.owl	regulation of LTD|regulation of long term synaptic depression|regulation of long term depression							rl	2012-04-27T03:54:58Z					biological_process											owl:Class	
GO:0048167	biolink:NamedThing	regulation of synaptic plasticity	A process that modulates synaptic plasticity, the ability of synapses to change as circumstances require. They may alter function, such as increasing or decreasing their sensitivity, or they may increase or decrease in actual numbers.	tmpzr1t_l9r_go_relaxed.owl						Note that the syntax of the definition of this term is different from the usual regulation syntax because it describes regulation of a trait rather than regulation of a process.								biological_process											owl:Class	
GO:0033670	biolink:NamedThing	regulation of NAD+ kinase activity	Any process that modulates the frequency, rate or extent of NAD kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to an NAD molecule.	tmpzr1t_l9r_go_relaxed.owl	NAD kinase regulator|regulation of NAD kinase activity													biological_process											owl:Class	
GO:0060379	biolink:NamedThing	cardiac muscle cell myoblast differentiation	The process in which a relatively unspecialized cell acquires specialized features of a cardiac myoblast. A cardiac myoblast is a precursor cell that has been committed to a cardiac muscle cell fate but retains the ability to divide and proliferate throughout life.	tmpzr1t_l9r_go_relaxed.owl	myocardial precursor cell differentiation|cardiac myoblast differentiation													biological_process											owl:Class	
GO:0010002	biolink:NamedThing	cardioblast differentiation	The process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.	tmpzr1t_l9r_go_relaxed.owl	cardioblast cell differentiation|cardiomyocyte generation|cardiac precursor cell differentiation													biological_process											owl:Class	
GO:0042339	biolink:NamedThing	keratan sulfate metabolic process	The chemical reactions and pathways involving keratan sulfate, a glycosaminoglycan with repeat units consisting of beta-1,4-linked D-galactopyranosyl-beta-(1,4)-N-acetyl-D-glucosamine 6-sulfate and with variable amounts of fucose, sialic acid and mannose units; keratan sulfate chains are covalently linked by a glycosidic attachment through the trisaccharide galactosyl-galactosyl-xylose to peptidyl-threonine or serine residues.	tmpzr1t_l9r_go_relaxed.owl	keratan sulfate metabolism|keratan sulphate metabolism|keratan sulphate metabolic process													biological_process											owl:Class	
GO:1903510	biolink:NamedThing	mucopolysaccharide metabolic process	The chemical reactions and pathways involving mucopolysaccharide.	tmpzr1t_l9r_go_relaxed.owl	mucopolysaccharide metabolism							dph	2014-10-01T21:55:47Z					biological_process											owl:Class	
GO:0090685	biolink:NamedThing	RNA localization to nucleus	A macromolecular localization process in which RNA is transported to and maintained in a location within the nucleus.	tmpzr1t_l9r_go_relaxed.owl	RNA localisation to nucleus							tb	2016-07-19T17:00:49Z					biological_process											owl:Class	
GO:0006403	biolink:NamedThing	RNA localization	A process in which RNA is transported to, or maintained in, a specific location.	tmpzr1t_l9r_go_relaxed.owl	RNA localisation|establishment and maintenance of RNA localization													biological_process											owl:Class	
GO:0008119	biolink:NamedThing	thiopurine S-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + a thiopurine = S-adenosyl-L-homocysteine + a thiopurine S-methylether.	tmpzr1t_l9r_go_relaxed.owl	mercaptopurine methyltransferase activity|TPMT|6-thiopurine transmethylase activity|S-adenosyl-L-methionine:thiopurine S-methyltransferase activity|thiopurine methyltransferase activity				MetaCyc:THIOPURINE-S-METHYLTRANSFERASE-RXN|EC:2.1.1.67|Reactome:R-HSA-158609|Reactome:R-HSA-5603379									molecular_function											owl:Class	
GO:0061388	biolink:NamedThing	regulation of rate of cell growth	Any process that modulates the rate of cell growth.	tmpzr1t_l9r_go_relaxed.owl								dph	2011-07-14T10:18:06Z					biological_process											owl:Class	
GO:0001558	biolink:NamedThing	regulation of cell growth	Any process that modulates the frequency, rate, extent or direction of cell growth.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0003730	biolink:NamedThing	mRNA 3'-UTR binding	Binding to a 3' untranslated region of an mRNA molecule.	tmpzr1t_l9r_go_relaxed.owl	mRNA 3' UTR binding													molecular_function											owl:Class	
GO:0003729	biolink:NamedThing	mRNA binding	Binding to messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns.	tmpzr1t_l9r_go_relaxed.owl	base pairing with mRNA											GO:0000499		molecular_function											owl:Class	
GO:0061076	biolink:NamedThing	negative regulation of neural retina development	Any process that decreases the rate, frequency, or extent of neural retina development, the progression of the neural retina over time from its initial formation to the mature structure. The neural retina is the part of the retina that contains neurons and photoreceptor cells.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-03-16T12:46:11Z					biological_process											owl:Class	
GO:0061074	biolink:NamedThing	regulation of neural retina development	Any process that modulates the rate, frequency, or extent of neural retina development, the progression of the neural retina over time from its initial formation to the mature structure. The neural retina is the part of the retina that contains neurons and photoreceptor cells.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-03-16T11:47:05Z					biological_process											owl:Class	
GO:0062123	biolink:NamedThing	regulation of linear element maturation	Any process that modulates the rate, frequency or extent of linear element maturation.	tmpzr1t_l9r_go_relaxed.owl								dph	2019-04-23T13:36:20Z					biological_process											owl:Class	
GO:0004304	biolink:NamedThing	estrone sulfotransferase activity	Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + estrone = adenosine 3',5'-bisphosphate + estrone 3-sulfate.	tmpzr1t_l9r_go_relaxed.owl	3'-phosphoadenylyl-sulfate:estrone 3-sulfotransferase activity|3'-phosphoadenylyl sulfate-estrone 3-sulfotransferase activity|3'-phosphoadenylylsulfate:oestrone sulfotransferase activity|estrogen sulphotransferase activity|estrogen sulfotransferase|oestrogen sulphotransferase activity|estrone sulphotransferase activity				RHEA:15973|MetaCyc:ESTRONE-SULFOTRANSFERASE-RXN|Reactome:R-HSA-176664|EC:2.8.2.4									molecular_function											owl:Class	
GO:0044489	biolink:NamedThing	negative regulation of voltage-gated sodium channel activity in other organism	Any process in which an organism stops, prevents or reduces the frequency, rate or extent of the activity of a voltage-gated sodium channel in another organism.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-02-01T12:21:02Z					biological_process											owl:Class	
GO:0044362	biolink:NamedThing	negative regulation of molecular function in other organism	Any process in which an organism stops, prevents or reduces the frequency, rate or extent of the function of proteins in a second organism.	tmpzr1t_l9r_go_relaxed.owl								jl	2011-10-27T02:12:49Z					biological_process											owl:Class	
GO:0061815	biolink:NamedThing	deubiquitinase, acting on linear ubiquitin	Catalysis of the hydrolysis of ubiquitin units from linear ubiquitin chains.	tmpzr1t_l9r_go_relaxed.owl	Met1 linkage specific DUB|linear ubiquitin specific deubiquitinase activity|ubiquitinyl hydrolase activity, acting on linear ubiquitin							dph	2016-11-28T13:58:44Z					molecular_function											owl:Class	
GO:0102030	biolink:NamedThing	dTDP-L-rhamnose synthetase activity	Catalysis of the reaction: dTDP-6-deoxy-beta-L-mannose + NAD+ <=> dTDP-4-dehydro-6-deoxy-alpha-D-glucose + NADH + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:DTDPRHAMSYNTHMULTI-RXN									molecular_function											owl:Class	
GO:0042476	biolink:NamedThing	odontogenesis	The process whose specific outcome is the progression of a tooth or teeth over time, from formation to the mature structure(s). A tooth is any hard bony, calcareous, or chitinous organ found in the mouth or pharynx of an animal and used in procuring or masticating food.	tmpzr1t_l9r_go_relaxed.owl	odontogeny|tooth morphogenesis|odontosis|tooth development|odontogenesis of calcareous or chitinous tooth				Wikipedia:Odontogenesis							GO:0042477		biological_process											owl:Class	
GO:0006081	biolink:NamedThing	cellular aldehyde metabolic process	The chemical reactions and pathways involving aldehydes, any organic compound with the formula R-CH=O, as carried out by individual cells.	tmpzr1t_l9r_go_relaxed.owl	alkanal metabolism|alkanal metabolic process|aldehyde metabolism													biological_process											owl:Class	
GO:0071704	biolink:NamedThing	organic substance metabolic process	The chemical reactions and pathways involving an organic substance, any molecular entity containing carbon.	tmpzr1t_l9r_go_relaxed.owl	organic molecular entity metabolism|organic molecular entity metabolic process|organic substance metabolism							mah	2010-03-08T03:32:18Z					biological_process											owl:Class	
GO:0033025	biolink:NamedThing	regulation of mast cell apoptotic process	Any process that modulates the frequency, rate, or extent of mast cell apoptotic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of mast cell apoptosis													biological_process											owl:Class	
GO:1902485	biolink:NamedThing	L-cysteine binding	Binding to L-cysteine.	tmpzr1t_l9r_go_relaxed.owl								bhm	2013-11-12T09:06:28Z					molecular_function											owl:Class	
GO:1900193	biolink:NamedThing	regulation of oocyte maturation	Any process that modulates the frequency, rate or extent of oocyte maturation.	tmpzr1t_l9r_go_relaxed.owl								kmv	2012-03-19T09:41:18Z					biological_process											owl:Class	
GO:2000241	biolink:NamedThing	regulation of reproductive process	Any process that modulates the frequency, rate or extent of reproductive process.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-11-10T02:44:02Z					biological_process											owl:Class	
GO:0032081	biolink:NamedThing	negative regulation of type II site-specific deoxyribonuclease activity	Any process that stops or reduces the rate of type II restriction endodeoxyribonuclease activity.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of type II restriction endodeoxyribonuclease activity|down regulation of type II restriction endodeoxyribonuclease activity|type II restriction enzyme inhibitor|down-regulation of type II restriction endodeoxyribonuclease activity|downregulation of type II restriction endodeoxyribonuclease activity|inhibition of type II restriction endodeoxyribonuclease activity|type II restriction endodeoxyribonuclease inhibitor													biological_process											owl:Class	
GO:0005464	biolink:NamedThing	UDP-xylose transmembrane transporter activity	Enables the transfer of UDP-xylose from one side of a membrane to the other. UDP-xylose is a substance composed of xylose in glycosidic linkage with uridine diphosphate.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-742373									molecular_function											owl:Class	
GO:0015165	biolink:NamedThing	pyrimidine nucleotide-sugar transmembrane transporter activity	Enables the transfer of a pyrimidine nucleotide-sugar from one side of a membrane to the other. Pyrimidine nucleotide-sugars are pyrimidine nucleotides in glycosidic linkage with a monosaccharide or monosaccharide derivative.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0060297	biolink:NamedThing	regulation of sarcomere organization	Any process that modulates the rate, frequency or extent of myofibril assembly by organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs.	tmpzr1t_l9r_go_relaxed.owl	regulation of sarcomere organisation													biological_process											owl:Class	
GO:1902903	biolink:NamedThing	regulation of supramolecular fiber organization	Any process that modulates the frequency, rate or extent of supramolecular fiber organization.	tmpzr1t_l9r_go_relaxed.owl	regulation of fibril organisation					HSPA8, human, P11142 in PMID:23921388 inferred from direct assay to negatively regulate fibrillation of alpha-Syn in vitro		rl	2014-04-15T16:46:36Z					biological_process											owl:Class	
GO:0001050	biolink:NamedThing	single-subunit type RNA polymerase binding	Binding to a single subunit RNA polymerase enzyme, which is composed of a single catalytic subunit similar to the RNA polymerase enzymes from phages T3, T7, and SP6.	tmpzr1t_l9r_go_relaxed.owl	T3/T7 type RNA polymerase binding|SP6-type RNA polymerase binding|T3-type RNA polymerase binding|T7-type RNA polymerase binding							krc	2010-09-23T02:33:45Z					molecular_function											owl:Class	
GO:0070063	biolink:NamedThing	RNA polymerase binding	Binding to an RNA polymerase molecule or complex.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0048737	biolink:NamedThing	imaginal disc-derived appendage development	The process whose specific outcome is the progression of an appendage over time, from its formation in the imaginal disc to the mature structure. An appendage is an organ or part that is attached to the trunk of an organism.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0048736	biolink:NamedThing	appendage development	The process whose specific outcome is the progression of an appendage over time, from its formation to the mature structure. An appendage is an organ or part that is attached to the trunk of an organism, such as a limb or a branch.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0031638	biolink:NamedThing	zymogen activation	The proteolytic processing of an inactive enzyme to an active form.	tmpzr1t_l9r_go_relaxed.owl	zymogen activation by proteolytic cleavage													biological_process											owl:Class	
GO:0016485	biolink:NamedThing	protein processing	Any protein maturation process achieved by the cleavage of a peptide bond or bonds within a protein. Protein maturation is the process leading to the attainment of the full functional capacity of a protein.	tmpzr1t_l9r_go_relaxed.owl	protein maturation by peptide bond cleavage|protein maturation by peptide bond hydrolysis|protein maturation by proteolysis|peptidolysis during protein maturation											GO:0051605		biological_process											owl:Class	
GO:1902929	biolink:NamedThing	plasma membrane of growing cell tip	Any plasma membrane part that is part of a growing cell tip.	tmpzr1t_l9r_go_relaxed.owl	plasma membrane part of growing cell end|plasma membrane part of growing cell tip|growing cell tip plasma membrane part							mah	2014-04-22T16:02:06Z					cellular_component											owl:Class	
GO:0098590	biolink:NamedThing	plasma membrane region	A membrane that is a (regional) part of the plasma membrane.	tmpzr1t_l9r_go_relaxed.owl	region of plasma membrane					Note that this term should not be used for direct manual annotation as it should always be possible to choose a more specific subclass.		dos	2014-03-06T11:55:32Z					cellular_component											owl:Class	
GO:0090181	biolink:NamedThing	regulation of cholesterol metabolic process	Any process that modulates the rate, frequency, or extent of cholesterol metabolism, the chemical reactions and pathways involving cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-12-18T10:33:49Z					biological_process											owl:Class	
GO:1990015	biolink:NamedThing	ensheathing process	A cell projection (often from glial cells such as Schwann cells) that surrounds an unmyelinated axon or cell soma.	tmpzr1t_l9r_go_relaxed.owl	ensheathing process of Schwann cell				NIF_Subcellular:sao1376748732			pr	2012-12-19T09:42:15Z					cellular_component											owl:Class	
GO:1900155	biolink:NamedThing	negative regulation of bone trabecula formation	Any process that stops, prevents or reduces the frequency, rate or extent of bone trabecula formation.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of skeletal trabecula formation|down-regulation of bone trabecula biogenesis|down-regulation of bone trabecula formation|down regulation of bone trabecula biogenesis|down-regulation of skeletal trabecula biogenesis|down regulation of skeletal trabecula formation|negative regulation of skeletal trabecula biogenesis|inhibition of skeletal trabecula biogenesis|down regulation of bone trabecula formation|down regulation of bone trabeculation|inhibition of skeletal trabeculation|inhibition of skeletal trabecula formation|inhibition of bone trabecula formation|negative regulation of bone trabeculation|negative regulation of bone trabecula biogenesis|inhibition of bone trabeculation|downregulation of bone trabeculation|inhibition of bone trabecula biogenesis|down regulation of skeletal trabeculation|down-regulation of bone trabeculation|downregulation of skeletal trabeculation|down-regulation of skeletal trabeculation|downregulation of bone trabecula formation|downregulation of skeletal trabecula formation|negative regulation of skeletal trabecula formation|downregulation of bone trabecula biogenesis|negative regulation of skeletal trabeculation|down regulation of skeletal trabecula biogenesis|downregulation of skeletal trabecula biogenesis							vk	2012-03-07T01:47:07Z					biological_process											owl:Class	
GO:1900570	biolink:NamedThing	diorcinol metabolic process	The chemical reactions and pathways involving diorcinol.	tmpzr1t_l9r_go_relaxed.owl	diorcinol metabolism							di	2012-05-15T06:35:01Z					biological_process											owl:Class	
GO:0018958	biolink:NamedThing	phenol-containing compound metabolic process	The chemical reactions and pathways involving a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring.	tmpzr1t_l9r_go_relaxed.owl	hydroxybenzene metabolism|carbolic acid metabolism|phenol-containing compound metabolism|carbolic acid metabolic process|hydroxybenzene metabolic process				UM-BBD_pathwayID:phe	Note that phenol metabolism is not included as a child of 'xenobiotic metabolism' because although it is synthesized industrially, phenol is also found naturally in animal wastes and other organic materials. It is often formed by the activity of microorganisms, which can chemically modify a variety of xenobiotic and naturally occurring phenolic compounds.								biological_process											owl:Class	
GO:0019417	biolink:NamedThing	sulfur oxidation	The chemical reactions and pathways resulting the addition of oxygen to elemental sulfur.	tmpzr1t_l9r_go_relaxed.owl	sulphur oxidation													biological_process											owl:Class	
GO:0047133	biolink:NamedThing	dimethylamine dehydrogenase activity	Catalysis of the reaction: electron-transferring flavoprotein + H2O + dimethylamine = reduced electron-transferring flavoprotein + formaldehyde + methylamine.	tmpzr1t_l9r_go_relaxed.owl	dimethylamine:electron-transferring flavoprotein oxidoreductase activity|DMADh activity				EC:1.5.8.1|UM-BBD_reactionID:r1380|RHEA:10204|MetaCyc:1.5.8.1-RXN									molecular_function											owl:Class	
GO:0046997	biolink:NamedThing	oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH group acts as a hydrogen or electron donor and reduces a flavin.	tmpzr1t_l9r_go_relaxed.owl					EC:1.5.8.-									molecular_function											owl:Class	
GO:0051767	biolink:NamedThing	nitric-oxide synthase biosynthetic process	The chemical reactions and pathways resulting in the formation of a nitric-oxide synthase, an enzyme which catalyzes the reaction L-arginine + n NADPH + n H+ + m O2 = citrulline + nitric oxide + n NADP+.	tmpzr1t_l9r_go_relaxed.owl	nitric-oxide synthase 2 biosynthetic process|nitric-oxide synthase (type 2) biosynthetic process|nitric-oxide synthase (type II) biosynthetic process|nitric-oxide synthase-1 biosynthetic process|NOS2 biosynthesis|NO synthase biosynthesis|NOS2 synthase biosynthesis|NO synthase biosynthetic process|NOS biosynthesis|NOS biosynthetic process|NOS3 biosynthesis|nitric-oxide synthase (type II) biosynthesis|inducible nitric-oxide synthase biosynthetic process|NOS1 biosynthesis|NOS2 synthase biosynthetic process|brain nitric-oxide synthase biosynthetic process|nitric-oxide synthase-3 biosynthetic process|nitric-oxide synthase-2 biosynthetic process|nitric-oxide synthase (type 2) biosynthesis|endothelial nitric-oxide synthase biosynthetic process											GO:0051768		biological_process											owl:Class	
GO:0031416	biolink:NamedThing	NatB complex	A conserved complex that catalyzes the transfer of an acetyl group to the N-terminal residue of a protein acceptor molecule that has a Met-Glu, Met-Asp, Met-Asn, or Met-Met N-terminus. In Saccharomyces the complex includes Nat3p and Mdm20p.	tmpzr1t_l9r_go_relaxed.owl	N-terminal acetyltransferase B complex													cellular_component											owl:Class	
GO:0031414	biolink:NamedThing	N-terminal protein acetyltransferase complex	A complex that catalyzes the transfer of an acetyl group to the N-terminal residue of a protein acceptor molecule.	tmpzr1t_l9r_go_relaxed.owl	NAT complex													cellular_component											owl:Class	
GO:0002082	biolink:NamedThing	regulation of oxidative phosphorylation	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the phosphorylation of ADP to ATP that accompanies the oxidation of a metabolite through the operation of the respiratory chain. Oxidation of compounds establishes a proton gradient across the membrane, providing the energy for ATP synthesis.	tmpzr1t_l9r_go_relaxed.owl	OXPHOS													biological_process											owl:Class	
GO:1903715	biolink:NamedThing	regulation of aerobic respiration	Any process that modulates the frequency, rate or extent of aerobic respiration.	tmpzr1t_l9r_go_relaxed.owl								al	2014-12-08T00:40:37Z					biological_process											owl:Class	
GO:0050813	biolink:NamedThing	epothilone metabolic process	The chemical reactions and pathways involving epothilone, a drug obtained from the myxobacteria Sporangium cellulosum that interferes with cell division. Some epothilones are being studied as treatments for cancer.	tmpzr1t_l9r_go_relaxed.owl	epothilone metabolism													biological_process											owl:Class	
GO:1903041	biolink:NamedThing	regulation of chondrocyte hypertrophy	Any process that modulates the frequency, rate or extent of chondrocyte hypertrophy.	tmpzr1t_l9r_go_relaxed.owl								mr	2014-05-20T21:23:13Z					biological_process											owl:Class	
GO:0061181	biolink:NamedThing	regulation of chondrocyte development	Any process that modulates the rate, frequency, or extent of the process whose specific outcome is the progression of a chondrocyte over time, from its commitment to its mature state. Chondrocyte development does not include the steps involved in committing a chondroblast to a chondrocyte fate.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-07-14T08:28:52Z					biological_process											owl:Class	
GO:0044221	biolink:NamedThing	host cell synapse	The junction between a nerve fiber of one host neuron and another host neuron or muscle fiber or glial cell; the site of interneuronal communication.	tmpzr1t_l9r_go_relaxed.owl								jl	2009-11-12T03:03:59Z					cellular_component											owl:Class	
GO:0031121	biolink:NamedThing	equatorial microtubule organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of structures formed of microtubules and associated proteins at the midpoint of a cell.	tmpzr1t_l9r_go_relaxed.owl	equatorial microtubule organisation|equatorial microtubule organization and biogenesis													biological_process											owl:Class	
GO:0000226	biolink:NamedThing	microtubule cytoskeleton organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins.	tmpzr1t_l9r_go_relaxed.owl	microtubule cytoskeleton organization and biogenesis|microtubule cytoskeleton organisation|microtubule dynamics													biological_process											owl:Class	
GO:0006837	biolink:NamedThing	serotonin transport	The directed movement of serotonin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Serotonin (5-hydroxytryptamine) is a monoamine neurotransmitter occurring in the peripheral and central nervous systems.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0006812	biolink:NamedThing	cation transport	The directed movement of cations, atoms or small molecules with a net positive charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	trivalent inorganic cation transport|di-, tri-valent inorganic cation transport											GO:0006819|GO:0015674|GO:0072512		biological_process											owl:Class	
GO:0043624	biolink:NamedThing	cellular protein complex disassembly	The disaggregation of a protein complex into its constituent components, occurring at the level of an individual cell. Protein complexes may have other associated non-protein prosthetic groups, such as nucleic acids, metal ions or carbohydrate groups.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0032984	biolink:NamedThing	protein-containing complex disassembly	The disaggregation of a protein-containing macromolecular complex into its constituent components.	tmpzr1t_l9r_go_relaxed.owl	cellular macromolecule complex disassembly|macromolecule complex disassembly|protein complex disassembly											GO:0043241|GO:0034623		biological_process											owl:Class	
GO:1901010	biolink:NamedThing	(S)-reticuline metabolic process	The chemical reactions and pathways involving (S)-reticuline.	tmpzr1t_l9r_go_relaxed.owl	(S)-reticuline metabolism							yaf	2012-06-15T10:46:22Z					biological_process											owl:Class	
GO:0046445	biolink:NamedThing	benzyl isoquinoline alkaloid metabolic process	The chemical reactions and pathways involving benzyl isoquinoline alkaloids, compounds with bicyclic N-containing aromatic rings.	tmpzr1t_l9r_go_relaxed.owl	benzyl isoquinoline alkaloid metabolism													biological_process											owl:Class	
GO:0035923	biolink:NamedThing	flurbiprofen binding	Binding to flurbiprofen.	tmpzr1t_l9r_go_relaxed.owl	2-(2-fluoro-[1,1'-biphenyl-4-yl])propanoic acid binding							bf	2011-07-15T03:53:53Z					molecular_function											owl:Class	
GO:0043177	biolink:NamedThing	organic acid binding	Binding to an organic acid, any acidic compound containing carbon in covalent linkage.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:2000558	biolink:NamedThing	positive regulation of immunoglobulin production in mucosal tissue	Any process that activates or increases the frequency, rate or extent of immunoglobulin production in mucosal tissue.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of antibody production in mucosal tissue							ebc	2011-04-03T07:52:17Z					biological_process											owl:Class	
GO:0002639	biolink:NamedThing	positive regulation of immunoglobulin production	Any process that activates or increases the frequency, rate, or extent of immunoglobulin production.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of immunoglobulin secretion|up regulation of immunoglobulin production|up-regulation of immunoglobulin production|activation of immunoglobulin production|positive regulation of immunoglobulin biosynthetic process|upregulation of immunoglobulin production|stimulation of immunoglobulin production											GO:0051024|GO:0002642		biological_process											owl:Class	
GO:0106129	biolink:NamedThing	positive regulation of store-operated calcium entry	Any process that activates or increases the frequency, rate or extent of store-operated calcium entry.	tmpzr1t_l9r_go_relaxed.owl								hjd	2018-05-10T19:02:40Z					biological_process											owl:Class	
GO:0018883	biolink:NamedThing	caprolactam metabolic process	The chemical reactions and pathways involving caprolactam, hexahydro-2h-azepin-2-one, a cyclic amide of caproic acid used in manufacture of synthetic fibers of the polyamide type. It can cause local irritation.	tmpzr1t_l9r_go_relaxed.owl	caprolactam metabolism				UM-BBD_pathwayID:cap									biological_process											owl:Class	
GO:0060303	biolink:NamedThing	regulation of nucleosome density	Any process that modulates the number of nucleosomes in a given region of a chromosome.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0065008	biolink:NamedThing	regulation of biological quality	Any process that modulates a qualitative or quantitative trait of a biological quality. A biological quality is a measurable attribute of an organism or part of an organism, such as size, mass, shape, color, etc.	tmpzr1t_l9r_go_relaxed.owl	regulation of biological attribute|regulation of biological characteristic													biological_process											owl:Class	
GO:0098786	biolink:NamedThing	biofilm matrix disassembly	A process that results in the disassembly of a biofilm matrix.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0098784	biolink:NamedThing	biofilm matrix organization	A process that results in the assembly, arrangement of constituent parts, or disassembly of a biofilm matrix.	tmpzr1t_l9r_go_relaxed.owl	biofilm matrix organization and biogenesis													biological_process											owl:Class	
GO:1901325	biolink:NamedThing	response to antimycin A	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antimycin A stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2012-08-30T10:12:16Z					biological_process											owl:Class	
GO:0014070	biolink:NamedThing	response to organic cyclic compound	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic cyclic compound stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to organic cyclic substance													biological_process											owl:Class	
GO:0016048	biolink:NamedThing	detection of temperature stimulus	The series of events in which a temperature stimulus (hot or cold) is received and converted into a molecular signal.	tmpzr1t_l9r_go_relaxed.owl	detection of temperature|perception of temperature|detection of thermal stimulus													biological_process											owl:Class	
GO:0009266	biolink:NamedThing	response to temperature stimulus	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a temperature stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to thermal stimulus													biological_process											owl:Class	
GO:0035611	biolink:NamedThing	protein branching point deglutamylation	The removal of a branching point glutamate residue. A branching point glutamate connects a glutamate side chain to a gene-encoded glutamate residue.	tmpzr1t_l9r_go_relaxed.owl								bf	2010-11-18T01:11:21Z					biological_process											owl:Class	
GO:0035608	biolink:NamedThing	protein deglutamylation	The removal of a glutamate residue from a protein. Glutamate residues in proteins can be gene-encoded, or added as side chains during the protein modification process of polyglutamylation.	tmpzr1t_l9r_go_relaxed.owl	protein amino acid deglutamylation							bf	2010-11-18T01:04:38Z					biological_process											owl:Class	
GO:1903323	biolink:NamedThing	regulation of snoRNA metabolic process	Any process that modulates the frequency, rate or extent of snoRNA metabolic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of snoRNA metabolism							vw	2014-08-18T13:05:17Z					biological_process											owl:Class	
GO:0097552	biolink:NamedThing	mitochondrial double-strand break repair via homologous recombination	The repair of a double-strand break in mitochondrial DNA in which the broken DNA molecule is repaired using homologous sequences.	tmpzr1t_l9r_go_relaxed.owl	mtDSB repair via homologous recombination					Note that the processes of nuclear double-strand break repair and mitochondrial double-strand break repair are genetically separable.		pr	2014-01-22T10:09:10Z					biological_process											owl:Class	
GO:0097551	biolink:NamedThing	mitochondrial double-strand break repair	The repair of double-strand breaks in mitochondrial DNA via homologous and nonhomologous mechanisms to reform a continuous DNA helix.	tmpzr1t_l9r_go_relaxed.owl	mtDSB repair					Note that the processes of nuclear double-strand break repair and mitochondrial double-strand break repair are genetically separable.		pr	2014-01-22T10:06:54Z					biological_process											owl:Class	
GO:0090707	biolink:NamedThing	establishment of plant organ orientation	The process that determines the orientation of a plant organ or tissue with reference to an axis.	tmpzr1t_l9r_go_relaxed.owl								tb	2016-10-05T12:42:47Z					biological_process											owl:Class	
GO:0048560	biolink:NamedThing	establishment of anatomical structure orientation	The process that determines the orientation of an anatomical structure with reference to an axis.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0099054	biolink:NamedThing	presynapse assembly	The aggregation, arrangement and bonding together of a set of components to form a presynapse.	tmpzr1t_l9r_go_relaxed.owl	presynaptic terminal assembly|presynapse biogenesis													biological_process											owl:Class	
GO:0099172	biolink:NamedThing	presynapse organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a presynapse.	tmpzr1t_l9r_go_relaxed.owl	presynapse development|presynapse morphogenesis|presynapse organisation|presynapse organization and biogenesis													biological_process											owl:Class	
GO:0016614	biolink:NamedThing	oxidoreductase activity, acting on CH-OH group of donors	Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group act as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.	tmpzr1t_l9r_go_relaxed.owl	oxidoreductase activity, acting on the CH-OH group of donors, other acceptors				Reactome:R-HSA-1500781|EC:1.1.-.-									molecular_function											owl:Class	
GO:0010864	biolink:NamedThing	positive regulation of protein histidine kinase activity	Any process that increases the frequency, rate or extent of protein histidine kinase activity.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0032110	biolink:NamedThing	regulation of protein histidine kinase activity	Any process that modulates the frequency, rate or extent of protein histidine kinase activity.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0090258	biolink:NamedThing	negative regulation of mitochondrial fission	Any process that decreases the rate, frequency or extent of mitochondrial fission. Mitochondrial fission is the division of a mitochondrion within a cell to form two or more separate mitochondrial compartments.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of mitochondrial division							tb	2010-02-03T04:05:32Z					biological_process											owl:Class	
GO:0090140	biolink:NamedThing	regulation of mitochondrial fission	Any process that modulates the rate, frequency or extent of mitochondrial fission. Mitochondrial fission is the division of a mitochondrion within a cell to form two or more separate mitochondrial compartments.	tmpzr1t_l9r_go_relaxed.owl	regulation of mitochondrial division							tb	2009-12-08T02:20:48Z					biological_process											owl:Class	
GO:0043065	biolink:NamedThing	positive regulation of apoptotic process	Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process.	tmpzr1t_l9r_go_relaxed.owl	up regulation of apoptosis|activation of apoptosis|pro-apoptosis|stimulation of apoptosis|positive regulation of apoptosis|upregulation of apoptosis|up-regulation of apoptosis					This term should only be used when it is not possible to determine which phase or subtype of the apoptotic process is positively regulated by a gene product. Whenever detailed information is available, the more granular children terms should be used.								biological_process											owl:Class	
GO:1905120	biolink:NamedThing	cellular response to haloperidol	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a haloperidol stimulus.	tmpzr1t_l9r_go_relaxed.owl						Note that this term is in the subset of terms that should not be used for direct manual annotation of gene products. It was created to be used for cross-referencing by other ontologies. Direct annotations to this term may be amended during annotation QC.		dw	2016-04-08T12:36:47Z					biological_process											owl:Class	
GO:0097306	biolink:NamedThing	cellular response to alcohol	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alcohol stimulus.	tmpzr1t_l9r_go_relaxed.owl								pr	2012-05-15T03:49:51Z					biological_process											owl:Class	
GO:0072250	biolink:NamedThing	metanephric glomerular visceral epithelial cell fate commitment	The process in which the developmental fate of a cell becomes restricted such that it will develop into a metanephric glomerular visceral epithelial cell. A metanephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the metanephros.	tmpzr1t_l9r_go_relaxed.owl	metanephric podocyte cell fate commitment							mah	2010-03-19T03:46:41Z					biological_process											owl:Class	
GO:0072149	biolink:NamedThing	glomerular visceral epithelial cell fate commitment	The process in which the developmental fate of a cell becomes restricted such that it will develop into a glomerular visceral epithelial cell. A glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells.	tmpzr1t_l9r_go_relaxed.owl	podocyte cell fate commitment							mah	2010-02-24T02:08:03Z					biological_process											owl:Class	
GO:2000023	biolink:NamedThing	regulation of lateral root development	Any process that modulates the frequency, rate or extent of lateral root development.	tmpzr1t_l9r_go_relaxed.owl								tb	2010-08-05T11:24:50Z					biological_process											owl:Class	
GO:2000069	biolink:NamedThing	regulation of post-embryonic root development	Any process that modulates the frequency, rate or extent of post-embryonic root development.	tmpzr1t_l9r_go_relaxed.owl								tb	2010-08-23T11:31:32Z					biological_process											owl:Class	
GO:0032446	biolink:NamedThing	protein modification by small protein conjugation	A protein modification process in which one or more groups of a small protein, such as ubiquitin or a ubiquitin-like protein, are covalently attached to a target protein.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0070647	biolink:NamedThing	protein modification by small protein conjugation or removal	A protein modification process in which one or more groups of a small protein, such as ubiquitin or a ubiquitin-like protein, are covalently attached to or removed from a target protein.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-05-11T02:54:03Z					biological_process											owl:Class	
GO:0031222	biolink:NamedThing	arabinan catabolic process	The chemical reactions and pathways resulting in the breakdown of arabinan, a polysaccharide composed of arabinose residues.	tmpzr1t_l9r_go_relaxed.owl	arabinan degradation|arabinan breakdown|arabinan catabolism													biological_process											owl:Class	
GO:0000272	biolink:NamedThing	polysaccharide catabolic process	The chemical reactions and pathways resulting in the breakdown of a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically.	tmpzr1t_l9r_go_relaxed.owl	polysaccharide catabolism|polysaccharide breakdown|multicellular organismal polysaccharide catabolic process|polysaccharide degradation											GO:0044244		biological_process											owl:Class	
GO:0140159	biolink:NamedThing	borate export across plasma membrane	The directed movement of borate from inside of a cell, across the plasma membrane and into the extracellular region.	tmpzr1t_l9r_go_relaxed.owl								pg	2018-02-02T10:21:37Z					biological_process											owl:Class	
GO:0140115	biolink:NamedThing	export across plasma membrane	The directed movement of some substance from inside of a cell, across the plasma membrane and into the extracellular region.	tmpzr1t_l9r_go_relaxed.owl	efflux							pg	2017-10-24T14:38:16Z					biological_process											owl:Class	
GO:0070158	biolink:NamedThing	mitochondrial seryl-tRNA aminoacylation	The process of coupling serine to seryl-tRNA in a mitochondrion, catalyzed by seryl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0070127	biolink:NamedThing	tRNA aminoacylation for mitochondrial protein translation	The synthesis of aminoacyl tRNA by the formation of an ester bond between the 3'-hydroxyl group of the most 3' adenosine of the tRNA, to be used in ribosome-mediated polypeptide synthesis in a mitochondrion.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0051279	biolink:NamedThing	regulation of release of sequestered calcium ion into cytosol	Any process that modulates the frequency, rate or extent of the release into the cytosolic compartment of calcium ions sequestered in the endoplasmic reticulum or mitochondria.	tmpzr1t_l9r_go_relaxed.owl	regulation of release of sequestered calcium ion (Ca2+)|regulation of cytoplasmic release of sequestered calcium ion (Ca2+)|regulation of release of stored calcium ion (Ca2+)|regulation of calcium mobilization|regulation of calcium ion (Ca2+) mobilization|regulation of release of stored calcium ion (Ca2+) into cytosol|regulation of cytoplasmic release of stored calcium ion (Ca2+)|regulation of release of stored calcium ion (Ca2+) into cytoplasm													biological_process											owl:Class	
GO:0051282	biolink:NamedThing	regulation of sequestering of calcium ion	Any process that modulates the frequency, rate or extent of the binding or confining calcium ions such that they are separated from other components of a biological system.	tmpzr1t_l9r_go_relaxed.owl	regulation of sequestering of calcium ion (Ca2+)|regulation of sequestration of calcium ion (Ca2+)|regulation of calcium ion (Ca2+) retention|regulation of calcium ion (Ca2+) sequestering|regulation of retention of calcium ion (Ca2+)|regulation of calcium ion (Ca2+) sequestration|regulation of calcium ion (Ca2+) storage|regulation of storage of calcium ion (Ca2+)													biological_process											owl:Class	
GO:0030738	biolink:NamedThing	tyramine N-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + tyramine = N-methyltyramine + S-adenosyl-L-homocysteine + H(+).	tmpzr1t_l9r_go_relaxed.owl	tyramine methylpherase activity|DIB O-methyltransferase (3,5-diiodo-4-hydroxy-benzoic acid)|S-adenosyl-L-methionine:tyramine N-methyltransferase activity|S-adenosyl-methionine:tyramine N-methyltransferase activity				EC:2.1.1.27|MetaCyc:TYRAMINE-N-METHYLTRANSFERASE-RXN|RHEA:14865|KEGG_REACTION:R02384									molecular_function											owl:Class	
GO:0008582	biolink:NamedThing	regulation of synaptic assembly at neuromuscular junction	Any process that modulates the frequency, rate or extent of synaptic assembly at neuromuscular junctions.	tmpzr1t_l9r_go_relaxed.owl	regulation of synaptic growth at neuromuscular junction													biological_process											owl:Class	
GO:0051963	biolink:NamedThing	regulation of synapse assembly	Any process that modulates the frequency, rate or extent of synapse assembly, the aggregation, arrangement and bonding together of a set of components to form a synapse.	tmpzr1t_l9r_go_relaxed.owl	regulation of synaptogenesis|regulation of synapse biogenesis													biological_process											owl:Class	
GO:0005515	biolink:NamedThing	protein binding	Binding to a protein.	tmpzr1t_l9r_go_relaxed.owl	glycoprotein binding|protein amino acid binding											GO:0001948|GO:0045308		molecular_function											owl:Class	
GO:0032703	biolink:NamedThing	negative regulation of interleukin-2 production	Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-2 production.	tmpzr1t_l9r_go_relaxed.owl	inhibition of interleukin-2 production|down regulation of interleukin-2 production|negative regulation of interleukin-2 secretion|downregulation of interleukin-2 production|down-regulation of interleukin-2 production|negative regulation of interleukin-2 biosynthetic process|negative regulation of IL-2 production											GO:0045085|GO:1900041		biological_process											owl:Class	
GO:0032663	biolink:NamedThing	regulation of interleukin-2 production	Any process that modulates the frequency, rate, or extent of interleukin-2 production.	tmpzr1t_l9r_go_relaxed.owl	regulation of interleukin-2 secretion|regulation of IL-2 production|regulation of interleukin-2 biosynthetic process											GO:1900040|GO:0045076		biological_process											owl:Class	
GO:1900886	biolink:NamedThing	positive regulation of tridecane biosynthetic process	Any process that activates or increases the frequency, rate or extent of tridecane biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	up regulation of tridecane anabolism|positive regulation of tridecane formation|activation of tridecane biosynthesis|activation of tridecane anabolism|positive regulation of tridecane synthesis|positive regulation of tridecane biosynthesis|up regulation of tridecane formation|upregulation of tridecane anabolism|up-regulation of tridecane biosynthesis|positive regulation of tridecane anabolism|up regulation of tridecane biosynthetic process|activation of tridecane formation|up-regulation of tridecane biosynthetic process|up-regulation of tridecane anabolism|up-regulation of tridecane formation|up regulation of tridecane biosynthesis|up-regulation of tridecane synthesis|upregulation of tridecane formation|up regulation of tridecane synthesis|upregulation of tridecane biosynthetic process|upregulation of tridecane synthesis|upregulation of tridecane biosynthesis|activation of tridecane biosynthetic process|activation of tridecane synthesis							tt	2012-06-13T03:01:01Z					biological_process											owl:Class	
GO:0070961	biolink:NamedThing	positive regulation of neutrophil mediated killing of symbiont cell	Any process that increases the frequency, rate or extent of the directed killing of a symbiont target cell by a neutrophil.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of neutrophil mediated killing of symbiont cell|up regulation of neutrophil mediated killing of symbiont cell|upregulation of neutrophil mediated killing of symbiont cell|activation of neutrophil mediated killing of symbiont cell|stimulation of neutrophil mediated killing of symbiont cell							mah	2009-10-01T02:28:49Z					biological_process											owl:Class	
GO:0031157	biolink:NamedThing	regulation of aggregate size involved in sorocarp development	Any process that modulates the size of the aggregate formed during sorocarp formation.	tmpzr1t_l9r_go_relaxed.owl	regulation of aggregation during fruiting body formation|regulation of aggregation during fruiting body biosynthesis													biological_process											owl:Class	
GO:0019827	biolink:NamedThing	stem cell population maintenance	The process by which an organism or tissue maintains a population of stem cells of a single type.  This can be achieved by a number of mechanisms: stem cell asymmetric division maintains stem cell numbers; stem cell symmetric division increases them; maintenance of a stem cell niche maintains the conditions for commitment to the stem cell fate for some types of stem cell; stem cells may arise de novo from other cell types.	tmpzr1t_l9r_go_relaxed.owl	maintenance of pluripotency													biological_process											owl:Class	
GO:0044627	biolink:NamedThing	modulation of complement activation, classical pathway in other organism	A process that modulates the frequency, rate or extent of the classical pathway of complement activation, in a different organism.	tmpzr1t_l9r_go_relaxed.owl	regulation of complement activation, classical pathway in other organism							jl	2012-07-05T12:55:53Z					biological_process											owl:Class	
GO:0030450	biolink:NamedThing	regulation of complement activation, classical pathway	Any process that modulates the frequency, rate or extent of the classical pathway of complement activation.	tmpzr1t_l9r_go_relaxed.owl	regulation of complement cascade, classical pathway													biological_process											owl:Class	
GO:1902823	biolink:NamedThing	negative regulation of late endosome to lysosome transport	Any process that stops, prevents or reduces the frequency, rate or extent of late endosome to lysosome transport.	tmpzr1t_l9r_go_relaxed.owl	downregulation of late endosome to lysosome transport|down-regulation of late endosome to lysosome transport|down regulation of late endosome to lysosome transport|inhibition of late endosome to lysosome transport							pad	2014-03-31T10:08:51Z					biological_process											owl:Class	
GO:1903336	biolink:NamedThing	negative regulation of vacuolar transport	Any process that stops, prevents or reduces the frequency, rate or extent of vacuolar transport.	tmpzr1t_l9r_go_relaxed.owl	down regulation of vacuolar transport|downregulation of vacuolar transport|inhibition of vacuolar transport|down-regulation of vacuolar transport							vw	2014-08-18T13:16:11Z					biological_process											owl:Class	
GO:1903966	biolink:NamedThing	monounsaturated fatty acid biosynthetic process	The chemical reactions and pathways resulting in the formation of monounsaturated fatty acid.	tmpzr1t_l9r_go_relaxed.owl	monounsaturated fatty acid synthesis|monounsaturated fatty acid biosynthesis|monounsaturated fatty acid anabolism|monounsaturated fatty acid formation					For example, stearoyl-coenzyme A desaturase (Scd) catalyzes the desaturation of saturated fatty acids to monounsaturated fatty acids in mammals and yeast.		pr	2015-02-25T20:36:07Z					biological_process											owl:Class	
GO:0008610	biolink:NamedThing	lipid biosynthetic process	The chemical reactions and pathways resulting in the formation of lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent.	tmpzr1t_l9r_go_relaxed.owl	lipid anabolism|lipogenesis|lipid synthesis|lipid formation|lipid biosynthesis													biological_process											owl:Class	
GO:1905102	biolink:NamedThing	positive regulation of apoptosome assembly	Any process that activates or increases the frequency, rate or extent of apoptosome assembly.	tmpzr1t_l9r_go_relaxed.owl	up regulation of apoptosome assembly|activation of apoptosome assembly|activation of apoptosome formation|up regulation of apoptosome formation|up-regulation of apoptosome assembly|up-regulation of apoptosome formation|positive regulation of apoptosome formation|upregulation of apoptosome formation|upregulation of apoptosome assembly							bc	2016-04-04T08:57:59Z					biological_process											owl:Class	
GO:0031334	biolink:NamedThing	positive regulation of protein-containing complex assembly	Any process that activates or increases the frequency, rate or extent of protein complex assembly.	tmpzr1t_l9r_go_relaxed.owl	activation of protein complex assembly|up regulation of protein complex assembly|stimulation of protein complex assembly|up-regulation of protein complex assembly|upregulation of protein complex assembly|positive regulation of protein complex assembly													biological_process											owl:Class	
GO:1900289	biolink:NamedThing	negative regulation of coenzyme F420-dependent bicyclic nitroimidazole catabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of coenzyme F420-dependent bicyclic nitroimidazole catabolic process.	tmpzr1t_l9r_go_relaxed.owl	downregulation of coenzyme F420-dependent bicyclic nitroimidazole catabolic process|inhibition of coenzyme F420-dependent nitroimidazole breakdown|down regulation of coenzyme F420-dependent nitroimidazole catabolism|downregulation of coenzyme F420-dependent nitroimidazole reduction|down-regulation of coenzyme F420-dependent bicyclic nitroimidazole catabolic process|down-regulation of coenzyme F420-dependent nitroimidazole reduction|downregulation of coenzyme F420-dependent nitroreductase activity|negative regulation of coenzyme F420-dependent nitroimidazole reduction|inhibition of coenzyme F420-dependent nitroimidazole reduction|down regulation of coenzyme F420-dependent nitroreductase activity|downregulation of coenzyme F420-dependent nitroimidazole catabolism|inhibition of coenzyme F420-dependent nitroreductase activity|downregulation of coenzyme F420-dependent nitroimidazole breakdown|inhibition of coenzyme F420-dependent bicyclic nitroimidazole catabolic process|down-regulation of coenzyme F420-dependent nitroimidazole breakdown|down regulation of coenzyme F420-dependent nitroimidazole breakdown|down regulation of coenzyme F420-dependent nitroimidazole reduction|negative regulation of coenzyme F420-dependent nitroreductase activity|down-regulation of coenzyme F420-dependent nitroreductase activity|down-regulation of coenzyme F420-dependent nitroimidazole catabolism|down regulation of coenzyme F420-dependent bicyclic nitroimidazole catabolic process|negative regulation of coenzyme F420-dependent nitroimidazole catabolism|negative regulation of coenzyme F420-dependent nitroimidazole breakdown|inhibition of coenzyme F420-dependent nitroimidazole catabolism							tt	2012-04-05T06:02:51Z					biological_process											owl:Class	
GO:1900288	biolink:NamedThing	regulation of coenzyme F420-dependent bicyclic nitroimidazole catabolic process	Any process that modulates the frequency, rate or extent of coenzyme F420-dependent bicyclic nitroimidazole catabolic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of coenzyme F420-dependent nitroimidazole reduction|regulation of coenzyme F420-dependent nitroimidazole breakdown|regulation of coenzyme F420-dependent nitroreductase activity|regulation of coenzyme F420-dependent nitroimidazole catabolism							tt	2012-04-05T06:02:41Z					biological_process											owl:Class	
GO:0102425	biolink:NamedThing	myricetin 3-O-glucosyltransferase activity	Catalysis of the reaction: myricetin + UDP-alpha-D-glucose <=> myricetin 3-O-beta-D-glucopyranoside + UDP.	tmpzr1t_l9r_go_relaxed.owl					EC:2.4.1.91|MetaCyc:RXN-13822									molecular_function											owl:Class	
GO:1904964	biolink:NamedThing	positive regulation of phytol biosynthetic process	Any process that activates or increases the frequency, rate or extent of phytol biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	upregulation of phytol anabolism|positive regulation of phytol anabolism|up regulation of phytol biosynthesis|up-regulation of phytol biosynthesis|up-regulation of phytol formation|upregulation of phytol biosynthetic process|positive regulation of phytol synthesis|activation of phytol biosynthesis|up-regulation of phytol anabolism|activation of phytol anabolism|up regulation of phytol anabolism|positive regulation of phytol biosynthesis|up regulation of phytol synthesis|activation of phytol synthesis|upregulation of phytol synthesis|up regulation of phytol formation|upregulation of phytol biosynthesis|activation of phytol biosynthetic process|up-regulation of phytol biosynthetic process|upregulation of phytol formation|positive regulation of phytol formation|up-regulation of phytol synthesis|up regulation of phytol biosynthetic process|activation of phytol formation							tb	2016-02-11T00:42:07Z					biological_process											owl:Class	
GO:1904963	biolink:NamedThing	regulation of phytol biosynthetic process	Any process that modulates the frequency, rate or extent of phytol biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of phytol synthesis|regulation of phytol formation|regulation of phytol biosynthesis|regulation of phytol anabolism							tb	2016-02-11T00:41:51Z					biological_process											owl:Class	
GO:2000655	biolink:NamedThing	negative regulation of cellular response to testosterone stimulus	Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to testosterone stimulus.	tmpzr1t_l9r_go_relaxed.owl								vk	2011-05-02T03:23:59Z					biological_process											owl:Class	
GO:0048585	biolink:NamedThing	negative regulation of response to stimulus	Any process that stops, prevents, or reduces the frequency, rate or extent of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.	tmpzr1t_l9r_go_relaxed.owl	downregulation of response to stimulus|down-regulation of response to stimulus|inhibition of response to stimulus|down regulation of response to stimulus					Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.								biological_process											owl:Class	
GO:0071412	biolink:NamedThing	cellular response to genistein	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a genistein stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-12-14T03:10:04Z					biological_process											owl:Class	
GO:0033595	biolink:NamedThing	response to genistein	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a genistein stimulus.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0070305	biolink:NamedThing	response to cGMP	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cGMP (cyclic GMP, guanosine 3',5'-cyclophosphate) stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to 3',5' cGMP|response to guanosine 3',5'-cyclophosphate|response to 3',5'-cGMP|response to cyclic GMP													biological_process											owl:Class	
GO:1903788	biolink:NamedThing	positive regulation of glutathione biosynthetic process	Any process that activates or increases the frequency, rate or extent of glutathione biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	activation of glutathione formation|upregulation of glutathione biosynthetic process|upregulation of glutathione anabolism|up regulation of glutathione anabolism|up-regulation of glutathione biosynthetic process|up-regulation of glutathione anabolism|upregulation of glutathione formation|up regulation of glutathione biosynthesis|up regulation of glutathione synthesis|activation of glutathione biosynthetic process|positive regulation of glutathione biosynthesis|up-regulation of glutathione formation|up regulation of glutathione formation|positive regulation of glutathione synthesis|up-regulation of glutathione biosynthesis|positive regulation of glutathione anabolism|up regulation of glutathione biosynthetic process|upregulation of glutathione synthesis|activation of glutathione anabolism|positive regulation of glutathione formation|activation of glutathione synthesis|activation of glutathione biosynthesis|upregulation of glutathione biosynthesis|up-regulation of glutathione synthesis							bf	2015-01-08T17:15:07Z					biological_process											owl:Class	
GO:2000792	biolink:NamedThing	positive regulation of mesenchymal cell proliferation involved in lung development	Any process that activates or increases the frequency, rate or extent of mesenchymal cell proliferation involved in lung development.	tmpzr1t_l9r_go_relaxed.owl								pr	2011-06-24T01:53:56Z					biological_process											owl:Class	
GO:2000790	biolink:NamedThing	regulation of mesenchymal cell proliferation involved in lung development	Any process that modulates the frequency, rate or extent of mesenchymal cell proliferation involved in lung development.	tmpzr1t_l9r_go_relaxed.owl								pr	2011-06-24T01:53:50Z					biological_process											owl:Class	
GO:0001227	biolink:NamedThing	DNA-binding transcription repressor activity, RNA polymerase II-specific	A DNA-binding transcription factor activity that represses or decreases the transcription of specific gene sets transcribed by RNA polymerase II.	tmpzr1t_l9r_go_relaxed.owl	transcriptional repressor activity, metal ion regulated sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription|distal enhancer DNA-binding transcription repressor activity, RNA polymerase II-specific|transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding|RNA polymerase II transcriptional repressor activity, metal ion regulated proximal promoter sequence-specific DNA binding|proximal promoter DNA-binding transcription repressor activity, RNA polymerase II-specific|RNA polymerase II distal enhancer sequence-specific DNA-binding transcription factor activity involved in negative regulation of transcription|transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding|RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription|RNA polymerase II transcriptional repressor activity, metal ion regulated core promoter proximal region sequence-specific binding|metal ion regulated sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription|metal ion regulated core promoter proximal region sequence-specific DNA binding RNA polymerase II transcription factor activity involved in negative regulation of transcription|sequence-specific distal enhancer binding RNA polymerase II transcription factor activity involved in negative regulation of transcription|transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding	https://github.com/geneontology/go-ontology/issues/20253|https://github.com/geneontology/go-ontology/issues/16152|https://github.com/geneontology/go-ontology/issues/16131|https://github.com/geneontology/go-ontology/issues/16534				For usage guidance, see comment in GO:0003700 ; DNA-binding transcription factor activity.		krc	2010-10-26T03:56:48Z			GO:0001210|GO:0001078|GO:0001206|GO:0001214		molecular_function											owl:Class	
GO:0140110	biolink:NamedThing	transcription regulator activity	A molecular function that controls the rate, timing and/or magnitude of gene transcription. The function of transcriptional regulators is to modulate gene expression at the transcription step so that they are expressed in the right cell at the right time and in the right amount throughout the life of the cell and the organism. Genes are transcriptional units, and include bacterial operons.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/13588						pg	2017-10-18T07:05:44Z					molecular_function											owl:Class	
GO:0071138	biolink:NamedThing	alpha5-beta5-fibronectin-SFRP2 complex	A protein complex that consists of an alpha5-beta5 integrin complex bound to fibronectin and secreted frizzled-related protein 2.	tmpzr1t_l9r_go_relaxed.owl	ITGA5-ITGB5-FN-1-SFRP2 complex							mah	2009-11-13T02:30:31Z					cellular_component											owl:Class	
GO:1901071	biolink:NamedThing	glucosamine-containing compound metabolic process	The chemical reactions and pathways involving glucosamine-containing compounds (glucosamines).	tmpzr1t_l9r_go_relaxed.owl	glucosamine-containing compound metabolism|glucosamines metabolic process|glucosamines metabolism							bf	2012-07-02T03:18:04Z					biological_process											owl:Class	
GO:0006040	biolink:NamedThing	amino sugar metabolic process	The chemical reactions and pathways involving any amino sugar, sugars containing an amino group in place of a hydroxyl group.	tmpzr1t_l9r_go_relaxed.owl	amino sugar metabolism|aminosaccharide metabolic process|aminosaccharide metabolism													biological_process											owl:Class	
GO:1990820	biolink:NamedThing	response to mitotic DNA integrity checkpoint signaling	A process that occurs in response to signals generated as a result of mitotic DNA integrity checkpoint signaling.	tmpzr1t_l9r_go_relaxed.owl	response to signal involved in mitotic DNA integrity checkpoint							mah	2015-08-14T10:25:46Z					biological_process											owl:Class	
GO:0072414	biolink:NamedThing	response to mitotic cell cycle checkpoint signaling	A process that occurs in response to signals generated as a result of mitotic cell cycle checkpoint signaling.	tmpzr1t_l9r_go_relaxed.owl	response to mitotic cell cycle G1/S checkpoint signaling|response to signal involved in mitotic cell cycle G1/S checkpoint|mitotic G2/M transition checkpoint effector process|response to mitotic G2/M transition checkpoint signal|response to signal involved in mitotic G2/M transition checkpoint|response to signal involved in mitotic cell cycle checkpoint|mitotic cell cycle checkpoint effector process|mitotic cell cycle G1/S checkpoint effector process							mah	2010-12-08T03:50:43Z			GO:0072473|GO:0072455		biological_process											owl:Class	
GO:0009071	biolink:NamedThing	serine family amino acid catabolic process	The chemical reactions and pathways resulting in the breakdown of amino acids of the serine family, comprising cysteine, glycine, homoserine, selenocysteine and serine.	tmpzr1t_l9r_go_relaxed.owl	serine family amino acid breakdown|serine family amino acid degradation|serine family amino acid catabolism													biological_process											owl:Class	
GO:1901606	biolink:NamedThing	alpha-amino acid catabolic process	The chemical reactions and pathways resulting in the breakdown of an alpha-amino acid.	tmpzr1t_l9r_go_relaxed.owl	alpha-amino acid catabolism|alpha-amino acid breakdown|alpha-amino acid degradation							tb	2012-11-08T17:39:54Z					biological_process											owl:Class	
GO:0103078	biolink:NamedThing	quercetin 3-rhamnoside 7-O-rhamnosyltransferase activity	Catalysis of the reaction: H+ + quercetin 3-O-rhamnoside + UDP-L-rhamnose <=> quercetin-3-rhamnoside-7-rhamnoside + UDP.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXNQT-4162|RHEA:61184									molecular_function											owl:Class	
GO:0110109	biolink:NamedThing	negative regulation of imaginal disc-derived wing vein specification	Any process that stops, prevents, or reduces the frequency, rate or extent of imaginal disc-derived wing vein specification.	tmpzr1t_l9r_go_relaxed.owl								kmv	2018-07-05T13:55:37Z					biological_process											owl:Class	
GO:0035451	biolink:NamedThing	extrinsic component of stromal side of plastid thylakoid membrane	The component of a plastid thylakoid membrane consisting of gene products and protein complexes that are loosely bound to its stromal surface, but not integrated into the hydrophobic region.	tmpzr1t_l9r_go_relaxed.owl	extrinsic to stromal leaflet of plastid thylakoid membrane|peripheral to stromal side of plastid thylakoid membrane|extrinsic to stromal side of plastid thylakoid membrane							bf	2010-04-16T10:18:01Z					cellular_component											owl:Class	
GO:0045145	biolink:NamedThing	single-stranded DNA 5'-3' exodeoxyribonuclease activity	Catalysis of the sequential cleavage of nucleotides (such as mononucleotides or dinucleotides) from a free 5' terminus of a single-stranded DNA molecule.	tmpzr1t_l9r_go_relaxed.owl	ssDNA-specific 5'-3' exodeoxyribonuclease activity|single-stranded DNA specific 5'-3' exodeoxyribonuclease activity													molecular_function											owl:Class	
GO:0008297	biolink:NamedThing	single-stranded DNA exodeoxyribonuclease activity	Catalysis of the sequential cleavage of mononucleotides from a free 5' or 3' terminus of a single-stranded DNA molecule.	tmpzr1t_l9r_go_relaxed.owl	single-stranded DNA specific exodeoxyribonuclease activity|ssDNA-specific exodeoxyribonuclease activity													molecular_function											owl:Class	
GO:1900612	biolink:NamedThing	F-9775B metabolic process	The chemical reactions and pathways involving F-9775B.	tmpzr1t_l9r_go_relaxed.owl	F-9775B metabolism							di	2012-05-15T07:03:01Z					biological_process											owl:Class	
GO:0030638	biolink:NamedThing	polyketide metabolic process	The chemical reactions and pathways involving polyketides, any of a diverse group of natural products synthesized via linear poly-beta-ketones, which are themselves formed by repetitive head-to-tail addition of acetyl (or substituted acetyl) units indirectly derived from acetate (or a substituted acetate) by a mechanism similar to that for fatty acid biosynthesis but without the intermediate reductive steps.	tmpzr1t_l9r_go_relaxed.owl	polyketide metabolism													biological_process											owl:Class	
GO:0032770	biolink:NamedThing	positive regulation of monooxygenase activity	Any process that activates or increases the activity of a monooxygenase.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of monooxygenase activity|activation of monooxygenase activity|stimulation of monooxygenase activity|up regulation of monooxygenase activity|upregulation of monooxygenase activity													biological_process											owl:Class	
GO:0032768	biolink:NamedThing	regulation of monooxygenase activity	Any process that modulates the activity of a monooxygenase.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0003169	biolink:NamedThing	coronary vein morphogenesis	The process in which the anatomical structures of veins of the heart are generated and organized.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-10-08T10:45:41Z					biological_process											owl:Class	
GO:0048845	biolink:NamedThing	venous blood vessel morphogenesis	The process in which the anatomical structures of venous blood vessels are generated and organized. Veins are blood vessels that transport blood from the body and its organs to the heart.	tmpzr1t_l9r_go_relaxed.owl	venous morphogenesis|vein morphogenesis													biological_process											owl:Class	
GO:0009800	biolink:NamedThing	cinnamic acid biosynthetic process	The chemical reactions and pathways resulting in the formation of cinnamic acid, 3-phenyl-2-propenoic acid.	tmpzr1t_l9r_go_relaxed.owl	phenylpropenoic acid biosynthetic process|phenylpropenoic acid biosynthesis|cinnamic acid synthesis|phenylacrylic acid biosynthesis|cinnamylic acid biosynthesis|cinnamic acid biosynthesis|phenylacrylic acid biosynthetic process|cinnamic acid anabolism|cinnamylic acid biosynthetic process|cinnamic acid formation													biological_process											owl:Class	
GO:0009803	biolink:NamedThing	cinnamic acid metabolic process	The chemical reactions and pathways involving cinnamic acid, 3-phenyl-2-propenoic acid.	tmpzr1t_l9r_go_relaxed.owl	phenylpropenoic acid metabolic process|cinnamylic acid metabolism|cinnamic acid metabolism|phenylacrylic acid metabolism|phenylpropenoic acid metabolism|phenylacrylic acid metabolic process|cinnamylic acid metabolic process													biological_process											owl:Class	
GO:0060069	biolink:NamedThing	Wnt signaling pathway, regulating spindle positioning	The series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of the target cell and ending with the positioning of the mitotic spindle.	tmpzr1t_l9r_go_relaxed.owl	Wnt-activated signaling pathway, regulating spindle positioning|Wnt receptor signalling pathway, regulating spindle positioning|non-canonical Wnt signaling pathway|Wnt receptor signaling pathway, regulating spindle positioning													biological_process											owl:Class	
GO:0097728	biolink:NamedThing	9+0 motile cilium	A motile cilium where the axoneme has a ring of nine outer microtubule doublets but no central microtubules (and is therefore called a 9+0 axoneme).	tmpzr1t_l9r_go_relaxed.owl	nodal cilium|motile 9+0 cilium					This type of cilia may be present in solitary (classic nodal cilia in embryonic nodes) or in multiple copies (e.g. in the choroid plexus epithelium).		pr	2016-09-27T15:24:37Z					cellular_component											owl:Class	
GO:0031514	biolink:NamedThing	motile cilium	A cilium which may have a variable arrangement of axonemal microtubules and also contains molecular motors. It may beat with a whip-like pattern that promotes cell motility or transport of fluids and other cells across a cell surface, such as on epithelial cells that line the lumenal ducts of various tissues; or they may display a distinct twirling motion that directs fluid flow asymmetrically across the cellular surface to affect asymmetric body plan organization. Motile cilia can be found in single as well as multiple copies per cell.	tmpzr1t_l9r_go_relaxed.owl	motile cilia|microtubule-based flagellum|motile primary cilium|motile primary cilia|motile secondary cilium|nodal cilium											GO:0009434|GO:0031512		cellular_component											owl:Class	
GO:0003849	biolink:NamedThing	3-deoxy-7-phosphoheptulonate synthase activity	Catalysis of the reaction: D-erythrose 4-phosphate + H(2)O + phosphoenolpyruvate = 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate + phosphate.	tmpzr1t_l9r_go_relaxed.owl	3-deoxy-D-arabino-heptulosonate 7-phosphate synthetase activity|7-phospho-2-keto-3-deoxy-D-arabino-heptonate D-erythrose-4-phosphate lyase (pyruvate-phosphorylating) activity|DHAP synthase activity|DAHP synthase activity|phospho-2-keto-3-deoxyheptonate aldolase activity|phospho-2-keto-3-deoxyheptanoate aldolase activity|DS-Mn activity|2-dehydro-3-deoxyphosphoheptonate aldolase activity|deoxy-D-arabino-heptulosonate-7-phosphate synthetase activity|2-keto-3-deoxy-D-arabino-heptonic acid 7-phosphate synthetase activity|KDPH synthetase activity|7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate|phospho-2-dehydro-3-deoxyheptonate aldolase activity|7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate D-erythrose-4-phosphate lyase (pyruvate-phosphorylating) activity|D-erythrose-4-phosphate-lyase (pyruvate-phosphorylating) activity|phospho-2-keto-3-deoxyheptonic aldolase activity|phosphoenolpyruvate:D-erythrose-4-phosphate C-(1-carboxyvinyl)transferase (phosphate-hydrolysing, 2-carboxy-2-oxoethyl-forming)|2-dehydro-3-deoxy-phosphoheptonate aldolase activity|3-deoxy-D-arabino-heptolosonate-7-phosphate synthetase activity|KDPH synthase activity|DAH7-P synthase activity|3-deoxy-D-arabino-2-heptulosonic acid 7-phosphate synthetase activity|D-erythrose-4-phosphate-lyase activity|DS-Co activity|phospho-2-oxo-3-deoxyheptonate aldolase activity				KEGG_REACTION:R01826|EC:2.5.1.54|MetaCyc:DAHPSYN-RXN|RHEA:14717	Note that this function was formerly EC:4.1.2.15.								molecular_function											owl:Class	
GO:0016765	biolink:NamedThing	transferase activity, transferring alkyl or aryl (other than methyl) groups	Catalysis of the transfer of an alkyl or aryl (but not methyl) group from one compound (donor) to another (acceptor).	tmpzr1t_l9r_go_relaxed.owl	transferase activity, transferring alkyl or aryl groups, other than methyl groups				EC:2.5.1.-|Reactome:R-HSA-4419978|Reactome:R-HSA-4755545|Reactome:R-HSA-6782893							GO:0016766		molecular_function											owl:Class	
GO:0000019	biolink:NamedThing	regulation of mitotic recombination	Any process that modulates the frequency, rate or extent of DNA recombination during mitosis.	tmpzr1t_l9r_go_relaxed.owl	regulation of recombination within rDNA repeats													biological_process											owl:Class	
GO:0060384	biolink:NamedThing	innervation	The process in which a nerve invades a tissue and makes functional synaptic connection within the tissue.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0051726	biolink:NamedThing	regulation of cell cycle	Any process that modulates the rate or extent of progression through the cell cycle.	tmpzr1t_l9r_go_relaxed.owl	regulation of progression through cell cycle|mitotic cell cycle arrest|arrest of mitotic cell cycle progression|tumor suppressor|cell cycle arrest|negative regulation of cell cycle arrest|cell cycle regulation|cell cycle regulator|cell cycle modulation|positive regulation of cell cycle arrest|control of cell cycle progression|regulation of cell cycle progression|modulation of cell cycle progression|regulation of cell cycle arrest											GO:0071157|GO:0071156|GO:0071158|GO:0071850|GO:0007050|GO:0000074		biological_process											owl:Class	
GO:0099145	biolink:NamedThing	regulation of exocytic insertion of neurotransmitter receptor to postsynaptic membrane	Any process that modulates the frequency, rate or extent of exocytic fusion of neurotransmitter receptor containing vesicles into the postsynaptic membrane.	tmpzr1t_l9r_go_relaxed.owl								dos	2017-06-09T18:49:26Z					biological_process											owl:Class	
GO:0051223	biolink:NamedThing	regulation of protein transport	Any process that modulates the frequency, rate or extent of the directed movement of a protein into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0016087	biolink:NamedThing	ecdysiostatic hormone activity	The action characteristic of ecdysiostatic hormone, a peptide hormone that inhibits ecdysone secretion.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0005184	biolink:NamedThing	neuropeptide hormone activity	The action characteristic of a neuropeptide hormone, any peptide hormone that acts in the central nervous system. A neuropeptide is any of several types of molecules found in brain tissue, composed of short chains of amino acids; they include endorphins, enkephalins, vasopressin, and others. They are often localized in axon terminals at synapses and are classified as putative neurotransmitters, although some are also hormones.	tmpzr1t_l9r_go_relaxed.owl	neurohormone				Wikipedia:Neurohormone									molecular_function											owl:Class	
GO:1901794	biolink:NamedThing	3-(3-hydroxyphenyl)propanoate catabolic process	The chemical reactions and pathways resulting in the breakdown of 3-(3-hydroxyphenyl)propanoate.	tmpzr1t_l9r_go_relaxed.owl	3-(3-hydroxyphenyl)propanoate degradation|3-(3-hydroxyphenyl)propanoate breakdown|3-(3-hydroxyphenyl)propanoate catabolism							yaf	2013-01-16T11:47:17Z					biological_process											owl:Class	
GO:1904859	biolink:NamedThing	positive regulation of endothelial cell chemotaxis to vascular endothelial growth factor	Any process that activates or increases the frequency, rate or extent of endothelial cell chemotaxis to vascular endothelial growth factor.	tmpzr1t_l9r_go_relaxed.owl	upregulation of endothelial cell chemotaxis to vascular endothelial growth factor|activation of endothelial cell chemotaxis to vascular endothelial growth factor|up regulation of endothelial cell chemotaxis to vascular endothelial growth factor|up-regulation of endothelial cell chemotaxis to vascular endothelial growth factor							rph	2015-12-16T11:48:00Z					biological_process											owl:Class	
GO:0050921	biolink:NamedThing	positive regulation of chemotaxis	Any process that activates or increases the frequency, rate or extent of the directed movement of a motile cell or organism in response to a specific chemical concentration gradient.	tmpzr1t_l9r_go_relaxed.owl	activation of chemotaxis|up regulation of chemotaxis|up-regulation of chemotaxis|upregulation of chemotaxis|stimulation of chemotaxis													biological_process											owl:Class	
GO:0051263	biolink:NamedThing	microcin E492 biosynthetic process by siderophore ester modification of peptidyl-serine	The modification of serine to N-[5-(6-O-seryl-beta-glucosyl)-2,3-dihydroxybenzoyl]-O-[N-(2,3-dihydroxybenzoyl)-O-[N-(2,3-dihydroxybenzoyl)seryl]seryl]serine as found in microcin E492 produced from the mceA gene in plasmid pJAM229 of the E. coli VCS257 strain and the K. pneumoniae RYC492 strain.	tmpzr1t_l9r_go_relaxed.owl	microcin E492 anabolism by siderophore ester modification of peptidyl-serine|microcin E492 synthesis by siderophore ester modification of peptidyl-serine|microcin E492 formation by siderophore ester modification of peptidyl-serine				RESID:AA0374									biological_process											owl:Class	
GO:0018350	biolink:NamedThing	protein esterification	The addition of an ester group to a protein amino acid.	tmpzr1t_l9r_go_relaxed.owl	protein amino acid esterification													biological_process											owl:Class	
GO:0046947	biolink:NamedThing	hydroxylysine biosynthetic process	The chemical reactions and pathways resulting in the formation of hydroxylysine (5-hydroxy-2,6-diaminohexanoic acid), a chiral alpha-amino acid.	tmpzr1t_l9r_go_relaxed.owl	hydroxylysine biosynthesis|hydroxylysine anabolism|hydroxylysine synthesis|hydroxylysine formation													biological_process											owl:Class	
GO:0046946	biolink:NamedThing	hydroxylysine metabolic process	The chemical reactions and pathways involving hydroxylysine (5-hydroxy-2,6-diaminohexanoic acid), a chiral alpha-amino acid. Hydroxylysine is found in collagen and commonly has galactose and then glucose added sequentially by glycosyltransferases.	tmpzr1t_l9r_go_relaxed.owl	hydroxylysine metabolism													biological_process											owl:Class	
GO:0008730	biolink:NamedThing	L(+)-tartrate dehydratase activity	Catalysis of the reaction: L-tartrate = H(2)O + oxaloacetate.	tmpzr1t_l9r_go_relaxed.owl	tartaric acid dehydrase activity|L-(+)-tartaric acid dehydratase activity|tartrate dehydratase activity|L-tartrate dehydratase activity|(R,R)-tartrate hydro-lyase (oxaloacetate-forming)|(R,R)-tartrate hydro-lyase activity				KEGG_REACTION:R00339|RHEA:15413|EC:4.2.1.32|MetaCyc:LTARTDEHYDRA-RXN									molecular_function											owl:Class	
GO:1903923	biolink:NamedThing	positive regulation of protein processing in phagocytic vesicle	Any process that activates or increases the frequency, rate or extent of protein processing in phagocytic vesicle.	tmpzr1t_l9r_go_relaxed.owl	up regulation of protein processing in phagocytic vesicle|up regulation of protein processing in phagosome|up-regulation of peptidolysis during protein maturation in phagosome|activation of protein maturation by peptide bond cleavage in phagocytic vesicle|upregulation of peptidolysis during protein maturation in phagocytic vesicle|up regulation of protein maturation by peptide bond cleavage in phagosome|activation of protein maturation by proteolysis in phagosome|up-regulation of protein maturation by peptide bond hydrolysis in phagocytic vesicle|upregulation of protein maturation by proteolysis in phagosome|upregulation of protein maturation by peptide bond hydrolysis in phagosome|positive regulation of protein maturation by peptide bond cleavage in phagosome|positive regulation of protein maturation by peptide bond hydrolysis in phagocytic vesicle|activation of protein maturation by proteolysis in phagocytic vesicle|up-regulation of protein maturation by proteolysis in phagosome|activation of protein processing in phagocytic vesicle|positive regulation of protein processing in phagosome|activation of peptidolysis during protein maturation in phagosome|upregulation of protein processing in phagosome|up regulation of protein maturation by peptide bond cleavage in phagocytic vesicle|activation of protein processing in phagosome|up-regulation of protein maturation by proteolysis in phagocytic vesicle|positive regulation of protein maturation by peptide bond cleavage in phagocytic vesicle|upregulation of protein maturation by peptide bond cleavage in phagosome|up-regulation of protein processing in phagosome|up-regulation of protein maturation by peptide bond cleavage in phagocytic vesicle|upregulation of peptidolysis during protein maturation in phagosome|upregulation of protein maturation by proteolysis in phagocytic vesicle|activation of peptidolysis during protein maturation in phagocytic vesicle|upregulation of protein maturation by peptide bond hydrolysis in phagocytic vesicle|up regulation of protein maturation by proteolysis in phagocytic vesicle|positive regulation of protein maturation by proteolysis in phagocytic vesicle|up-regulation of peptidolysis during protein maturation in phagocytic vesicle|upregulation of protein maturation by peptide bond cleavage in phagocytic vesicle|up regulation of protein maturation by peptide bond hydrolysis in phagosome|up-regulation of protein maturation by peptide bond hydrolysis in phagosome|up-regulation of protein maturation by peptide bond cleavage in phagosome|activation of protein maturation by peptide bond hydrolysis in phagocytic vesicle|positive regulation of protein maturation by peptide bond hydrolysis in phagosome|positive regulation of peptidolysis during protein maturation in phagosome|upregulation of protein processing in phagocytic vesicle|positive regulation of peptidolysis during protein maturation in phagocytic vesicle|up regulation of protein maturation by proteolysis in phagosome|activation of protein maturation by peptide bond cleavage in phagosome|up regulation of protein maturation by peptide bond hydrolysis in phagocytic vesicle|up-regulation of protein processing in phagocytic vesicle|activation of protein maturation by peptide bond hydrolysis in phagosome|positive regulation of protein maturation by proteolysis in phagosome|up regulation of peptidolysis during protein maturation in phagocytic vesicle|up regulation of peptidolysis during protein maturation in phagosome							als	2015-02-10T11:17:14Z					biological_process											owl:Class	
GO:0046398	biolink:NamedThing	UDP-glucuronate metabolic process	The chemical reactions and pathways involving UDP-glucuronate, a substance composed of glucuronic acid in glycosidic linkage with uridine diphosphate.	tmpzr1t_l9r_go_relaxed.owl	UDP-glucuronate metabolism													biological_process											owl:Class	
GO:2000565	biolink:NamedThing	negative regulation of CD8-positive, alpha-beta T cell proliferation	Any process that stops, prevents or reduces the frequency, rate or extent of CD8-positive, alpha-beta T cell proliferation.	tmpzr1t_l9r_go_relaxed.owl								ebc	2011-04-03T09:03:19Z					biological_process											owl:Class	
GO:2001186	biolink:NamedThing	negative regulation of CD8-positive, alpha-beta T cell activation	Any process that stops, prevents or reduces the frequency, rate or extent of CD8-positive, alpha-beta T cell activation.	tmpzr1t_l9r_go_relaxed.owl								yaf	2011-11-03T01:16:57Z					biological_process											owl:Class	
GO:0015108	biolink:NamedThing	chloride transmembrane transporter activity	Enables the transfer of chloride ions from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	chloride ABC transporter|chloride transporting ATPase activity|chloride-transporting ATPase activity|ATPase-coupled chloride transmembrane transporter activity|ATP-dependent chloride transmembrane transporter activity|chloride ion transmembrane transporter activity				RHEA:29823|Reactome:R-HSA-5678863|Reactome:R-HSA-5678992|Reactome:R-HSA-5678822|MetaCyc:3.6.3.11-RXN							GO:0008555		molecular_function											owl:Class	
GO:0043225	biolink:NamedThing	ATPase-coupled inorganic anion transmembrane transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + inorganic anion(out) = ADP + phosphate + inorganic anion(in).	tmpzr1t_l9r_go_relaxed.owl	ATP-dependent anion transmembrane transporter activity|anion ABC transporter|anion transmembrane-transporting ATPase activity|anion-transporting ATPase activity|ATPase-coupled anion transmembrane transporter activity				Reactome:R-HSA-5690340|Reactome:R-HSA-1454916									molecular_function											owl:Class	
GO:0051581	biolink:NamedThing	negative regulation of neurotransmitter uptake	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a neurotransmitter into a neuron or glial cell.	tmpzr1t_l9r_go_relaxed.owl	down regulation of neurotransmitter uptake|negative regulation of neurotransmitter import|downregulation of neurotransmitter uptake|down-regulation of neurotransmitter uptake													biological_process											owl:Class	
GO:1900656	biolink:NamedThing	negative regulation of diorcinol biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of diorcinol biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of diorcinol biosynthesis|inhibition of diorcinol synthesis|down regulation of diorcinol anabolism|down-regulation of diorcinol formation|negative regulation of diorcinol synthesis|down-regulation of diorcinol synthesis|down regulation of diorcinol synthesis|down-regulation of diorcinol biosynthetic process|negative regulation of diorcinol anabolism|down-regulation of diorcinol anabolism|inhibition of diorcinol biosynthesis|downregulation of diorcinol synthesis|downregulation of diorcinol formation|downregulation of diorcinol biosynthetic process|down regulation of diorcinol formation|inhibition of diorcinol formation|down regulation of diorcinol biosynthetic process|downregulation of diorcinol anabolism|downregulation of diorcinol biosynthesis|inhibition of diorcinol biosynthetic process|negative regulation of diorcinol formation|negative regulation of diorcinol biosynthesis|inhibition of diorcinol anabolism|down regulation of diorcinol biosynthesis							di	2012-05-22T04:09:01Z					biological_process											owl:Class	
GO:0031327	biolink:NamedThing	negative regulation of cellular biosynthetic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances, carried out by individual cells.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of cellular biosynthetic process|inhibition of cellular biosynthetic process|downregulation of cellular biosynthetic process|negative regulation of cellular anabolism|down regulation of cellular biosynthetic process|negative regulation of cellular formation|negative regulation of cellular biosynthesis|negative regulation of cellular synthesis													biological_process											owl:Class	
GO:1904984	biolink:NamedThing	regulation of quinolinate biosynthetic process	Any process that modulates the frequency, rate or extent of quinolinate biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of quinolinate formation|regulation of quinolinate anabolism|regulation of quinolinate synthesis|regulation of quinolinate biosynthesis							bf	2016-02-29T15:54:12Z					biological_process											owl:Class	
GO:0007556	biolink:NamedThing	regulation of juvenile hormone metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving juvenile hormone.	tmpzr1t_l9r_go_relaxed.owl	regulation of juvenile hormone metabolism													biological_process											owl:Class	
GO:0090453	biolink:NamedThing	aspartate transmembrane import into vacuole	The directed movement of aspartate into the vacuole across the vacuolar membrane.	tmpzr1t_l9r_go_relaxed.owl	vacuolar aspartate import							tb	2012-09-24T14:12:46Z					biological_process											owl:Class	
GO:0034487	biolink:NamedThing	vacuolar amino acid transmembrane transport	The process in which an amino acid is transported from one side of the vacuolar membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	vacuolar amino acid membrane transport					Note that this term is not intended for use in annotating lateral movement within membranes.								biological_process											owl:Class	
GO:0098554	biolink:NamedThing	cytoplasmic side of endoplasmic reticulum membrane	The side (leaflet) of the plasma membrane that faces the cytoplasm.	tmpzr1t_l9r_go_relaxed.owl								dos	2013-12-03T12:09:47Z					cellular_component											owl:Class	
GO:0098562	biolink:NamedThing	cytoplasmic side of membrane	The side of a membrane that faces the cytoplasm.	tmpzr1t_l9r_go_relaxed.owl								dos	2013-12-12T11:21:30Z					cellular_component											owl:Class	
GO:1900727	biolink:NamedThing	osmoregulated periplasmic glucan biosynthetic process	The chemical reactions and pathways resulting in the formation of osmoregulated periplasmic glucan.	tmpzr1t_l9r_go_relaxed.owl	osmoregulated periplasmic glucan anabolism|osmoregulated periplasmic glucan formation|osmoregulated periplasmic glucan biosynthesis|osmoregulated periplasmic glucan synthesis							jl	2012-05-24T03:19:02Z					biological_process											owl:Class	
GO:0009250	biolink:NamedThing	glucan biosynthetic process	The chemical reactions and pathways resulting in the formation of glucans, polysaccharides consisting only of glucose residues.	tmpzr1t_l9r_go_relaxed.owl	glucan synthesis|glucan formation|glucan biosynthesis|glucan anabolism													biological_process											owl:Class	
GO:1901461	biolink:NamedThing	negative regulation of response to formic acid	Any process that stops, prevents or reduces the frequency, rate or extent of response to formic acid.	tmpzr1t_l9r_go_relaxed.owl	downregulation of response to formic acid|down regulation of response to formic acid|inhibition of response to formic acid|down-regulation of response to formic acid							tt	2012-10-02T14:29:02Z					biological_process											owl:Class	
GO:1901460	biolink:NamedThing	regulation of response to formic acid	Any process that modulates the frequency, rate or extent of response to formic acid.	tmpzr1t_l9r_go_relaxed.owl								tt	2012-10-02T14:27:54Z					biological_process											owl:Class	
GO:0015742	biolink:NamedThing	alpha-ketoglutarate transport	The directed movement of alpha-ketoglutarate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	2-oxoglutarate transport|mitochondrial alpha-ketoglutarate/malate transport													biological_process											owl:Class	
GO:0005847	biolink:NamedThing	mRNA cleavage and polyadenylation specificity factor complex	A multisubunit complex that binds to the canonical AAUAAA hexamer and to U-rich upstream sequence elements on the pre-mRNA, thereby stimulating the otherwise weakly active and nonspecific polymerase to elongate efficiently RNAs containing a poly(A) signal.	tmpzr1t_l9r_go_relaxed.owl	CPF complex|CPSF complex|CFII complex|cleavage and polyadenylylation specificity factor activity													cellular_component											owl:Class	
GO:0005849	biolink:NamedThing	mRNA cleavage factor complex	Any macromolecular complex involved in cleavage or polyadenylation of mRNA molecules.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0035540	biolink:NamedThing	positive regulation of SNARE complex disassembly	Any process that increases the frequency, rate or extent of disassembly of the SNARE complex. The SNARE complex is a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers.	tmpzr1t_l9r_go_relaxed.owl								bf	2010-05-10T01:42:21Z					biological_process											owl:Class	
GO:0002600	biolink:NamedThing	positive regulation of antigen processing and presentation of lipid antigen via MHC class Ib	Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of lipid antigen via MHC class Ib.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of antigen processing and presentation of lipid antigen via MHC class Ib|stimulation of antigen processing and presentation of lipid antigen via MHC class Ib|upregulation of antigen processing and presentation of lipid antigen via MHC class Ib|positive regulation of lipid antigen processing and presentation via MHC class Ib|activation of antigen processing and presentation of lipid antigen via MHC class Ib|up regulation of antigen processing and presentation of lipid antigen via MHC class Ib													biological_process											owl:Class	
GO:0002598	biolink:NamedThing	regulation of antigen processing and presentation of lipid antigen via MHC class Ib	Any process that modulates the frequency, rate, or extent of antigen processing and presentation of lipid antigen via MHC class Ib.	tmpzr1t_l9r_go_relaxed.owl	regulation of lipid antigen processing and presentation via MHC class Ib													biological_process											owl:Class	
GO:0035976	biolink:NamedThing	transcription factor AP-1 complex	A heterodimeric transcription factor complex composed of proteins from the c-Fos, c-Jun, activating transcription factor (ATF) or JDP families. The subunits contain a basic leucine zipper (bZIP) domain that is essential for dimerization and DNA binding. Jun-Fos heterodimers bind preferentially to a heptamer consensus sequence (TPA responsive element (TRE)), whereas Jun-ATF dimers bind the cyclic AMP responsive element (CRE) to regulate transcription of target genes.	tmpzr1t_l9r_go_relaxed.owl	AP1 complex|AP-1 complex|transcription factor AP1 complex|Activating protein 1 complex							bf	2011-08-17T10:57:51Z					cellular_component											owl:Class	
GO:0090575	biolink:NamedThing	RNA polymerase II transcription regulator complex	A transcription factor complex that acts at a regulatory region of a gene transcribed by RNA polymerase II.	tmpzr1t_l9r_go_relaxed.owl	RNA polymerase II transcription factor complex							tb	2014-05-09T14:04:37Z					cellular_component											owl:Class	
GO:1904810	biolink:NamedThing	negative regulation of dense core granule transport	Any process that stops, prevents or reduces the frequency, rate or extent of dense core granule transport.	tmpzr1t_l9r_go_relaxed.owl	downregulation of dense core granule transport|downregulation of dense core vesicle transport|down regulation of dense core vesicle transport|down regulation of dense core granule transport|inhibition of dense core vesicle transport|down-regulation of dense core granule transport|negative regulation of dense core vesicle transport|inhibition of dense core granule transport|down-regulation of dense core vesicle transport					cdk-5 in C.elegans (G5ECH7) in PMID:22699897 (inferred from mutant phenotype).		es	2015-11-11T10:40:18Z					biological_process											owl:Class	
GO:1904809	biolink:NamedThing	regulation of dense core granule transport	Any process that modulates the frequency, rate or extent of dense core granule transport.	tmpzr1t_l9r_go_relaxed.owl	regulation of dense core vesicle transport					cdk-5 in C.elegans (G5ECH7) in PMID:22699897 (inferred from mutant phenotype).		es	2015-11-11T10:40:10Z					biological_process											owl:Class	
GO:0038089	biolink:NamedThing	positive regulation of cell migration by vascular endothelial growth factor signaling pathway	A series of molecular signals initiated by the binding of a vascular endothelial growth factor (VEGF) to a receptor on the surface of a cell, which activates or increases the frequency, rate or extent of the orderly movement of a cell from one site to another.	tmpzr1t_l9r_go_relaxed.owl	VEGF-induced cell migration|VEGF-A-induced cell migration|positive regulation of cell migration by VEGF signaling pathway|positive regulation of cell migration by vascular endothelial growth factor signalling pathway							bf	2012-02-02T03:40:13Z					biological_process											owl:Class	
GO:0038084	biolink:NamedThing	vascular endothelial growth factor signaling pathway	A series of molecular signals initiated by the binding of a vascular endothelial growth factor (VEGF) to a receptor on the surface of the target cell, and ending with regulation of a downstream cellular process, e.g. transcription.	tmpzr1t_l9r_go_relaxed.owl	VEGF-activated signaling pathway|vascular endothelial growth factor signalling pathway|VEGF signaling					In GO, a gene product with 'vascular endothelial growth factor-activated receptor activity ; GO:0005021' necessarily binds VEGF to transduce a signal. To represent cross-talk between ligands and receptors, signaling pathways in GO are starting to be named after the receptor and/or the signal. GO:0038084 is for annotation of any pathway in which the ligand VEGF binds and activates any cell surface receptor (VEGFR, PDGFR etc.). For annotation of signaling pathways where a VEGFR binds one of its physiological ligands (VEGF or an alternative growth factor), consider 'vascular endothelial growth factor receptor signaling pathway ; GO:0048010'.		bf	2012-02-01T02:27:32Z					biological_process											owl:Class	
GO:2000521	biolink:NamedThing	negative regulation of immunological synapse formation	Any process that stops, prevents or reduces the frequency, rate or extent of immunological synapse formation.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of formation of immunological synapse							ebc	2011-03-23T10:18:19Z					biological_process											owl:Class	
GO:0051250	biolink:NamedThing	negative regulation of lymphocyte activation	Any process that stops, prevents, or reduces the frequency, rate or extent of lymphocyte activation.	tmpzr1t_l9r_go_relaxed.owl	downregulation of lymphocyte activation|down regulation of lymphocyte activation|down-regulation of lymphocyte activation|inhibition of lymphocyte activation													biological_process											owl:Class	
GO:0051001	biolink:NamedThing	negative regulation of nitric-oxide synthase activity	Any process that stops or reduces the activity of the enzyme nitric-oxide synthase.	tmpzr1t_l9r_go_relaxed.owl	inhibition of nitric-oxide synthase activity|nitric-oxide synthase inhibitor|negative regulation of NOS activity|NOS inhibitor|down-regulation of nitric-oxide synthase activity|downregulation of nitric-oxide synthase activity|down regulation of nitric-oxide synthase activity													biological_process											owl:Class	
GO:0048550	biolink:NamedThing	negative regulation of pinocytosis	Any process that stops, prevents, or reduces the frequency, rate or extent of pinocytosis. Pinocytosis is the process in which cells take in liquid material from their external environment; literally 'cell drinking'. Liquid is enclosed in vesicles, formed by invagination of the plasma membrane. These vesicles then move into the cell and pass their contents to endosomes.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of pinocytosis|inhibition of pinocytosis|down regulation of pinocytosis|downregulation of pinocytosis													biological_process											owl:Class	
GO:0048548	biolink:NamedThing	regulation of pinocytosis	Any process that modulates the frequency, rate or extent of pinocytosis. Pinocytosis is the process in which cells take in liquid material from their external environment; literally 'cell drinking'. Liquid is enclosed in vesicles, formed by invagination of the plasma membrane. These vesicles then move into the cell and pass their contents to endosomes.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0015871	biolink:NamedThing	choline transport	The directed movement of choline into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Choline (2-hydroxyethyltrimethylammonium) is an amino alcohol that occurs widely in living organisms as a constituent of certain types of phospholipids and in the neurotransmitter acetylcholine.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0015695	biolink:NamedThing	organic cation transport	The directed movement of organic cations into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Organic cations are atoms or small molecules with a positive charge which contain carbon in covalent linkage.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1901772	biolink:NamedThing	lincomycin metabolic process	The chemical reactions and pathways involving lincomycin.	tmpzr1t_l9r_go_relaxed.owl	lincomycin metabolism							yaf	2013-01-15T11:53:52Z					biological_process											owl:Class	
GO:0046483	biolink:NamedThing	heterocycle metabolic process	The chemical reactions and pathways involving heterocyclic compounds, those with a cyclic molecular structure and at least two different atoms in the ring (or rings).	tmpzr1t_l9r_go_relaxed.owl	heterocycle metabolism													biological_process											owl:Class	
GO:0006076	biolink:NamedThing	(1->3)-beta-D-glucan catabolic process	The chemical reactions and pathways resulting in the breakdown of (1->3)-beta-D-glucans.	tmpzr1t_l9r_go_relaxed.owl	1,3-beta-D-glucan catabolic process|1,3-beta-glucan degradation|beta-1,3 glucan catabolic process|beta-1,3 glucan degradation|1,3-beta-glucan breakdown|beta-1,3 glucan breakdown|beta-1,3 glucan catabolism|1,3-beta-glucan catabolism													biological_process											owl:Class	
GO:0051275	biolink:NamedThing	beta-glucan catabolic process	The chemical reactions and pathways resulting in the breakdown of beta-glucans.	tmpzr1t_l9r_go_relaxed.owl	beta-glucan degradation|beta-glucan catabolism|beta-glucan breakdown													biological_process											owl:Class	
GO:0060883	biolink:NamedThing	regulation of basement membrane disassembly involved in semicircular canal fusion by cell communication	Any process that mediates interactions between a cell and its surroundings that modulates of the rate, frequency or extent of basement membrane disassembly involved in semicircular canal fusion.	tmpzr1t_l9r_go_relaxed.owl	regulation of basal lamina disassembly involved in semicircular canal fusion by cell communication							dph	2009-08-13T11:31:56Z					biological_process											owl:Class	
GO:0110011	biolink:NamedThing	regulation of basement membrane organization	Any process that modulates the frequency, rate or extent of the assembly, disassembly or arrangement of constituent parts of the basement membrane.	tmpzr1t_l9r_go_relaxed.owl								kmv						biological_process											owl:Class	
GO:0003363	biolink:NamedThing	lamellipodium assembly involved in ameboidal cell migration	Formation of a lamellipodium, a thin sheetlike extension of the surface of a migrating cell that contributes to the directed self propelled movement of a cell.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-12-08T04:38:04Z					biological_process											owl:Class	
GO:0030032	biolink:NamedThing	lamellipodium assembly	Formation of a lamellipodium, a thin sheetlike extension of the surface of a migrating cell.	tmpzr1t_l9r_go_relaxed.owl	lamellipodium biogenesis|lamellipodium biosynthesis|lamellipodium formation													biological_process											owl:Class	
GO:0009436	biolink:NamedThing	glyoxylate catabolic process	The chemical reactions and pathways resulting in the breakdown of glyoxylate, the anion of glyoxylic acid, HOC-COOH.	tmpzr1t_l9r_go_relaxed.owl	glyoxylate degradation|glyoxylate breakdown|glyoxylate catabolism				MetaCyc:GLYOXDEG-PWY									biological_process											owl:Class	
GO:0046185	biolink:NamedThing	aldehyde catabolic process	The chemical reactions and pathways resulting in the breakdown of aldehydes, any organic compound with the formula R-CH=O.	tmpzr1t_l9r_go_relaxed.owl	aldehyde breakdown|aldehyde catabolism|aldehyde degradation													biological_process											owl:Class	
GO:0097063	biolink:NamedThing	cadmium ion sensor activity	Binding to and responding, e.g. by conformational change, to changes in the cellular level of cadmium (Cd++).	tmpzr1t_l9r_go_relaxed.owl								pr	2011-06-08T09:46:14Z					molecular_function											owl:Class	
GO:0140299	biolink:NamedThing	small molecule sensor activity	Binding to a small molecule and eliciting a change in the protein's activity in response to the intracellular level of that small molecule.	tmpzr1t_l9r_go_relaxed.owl	small molecular sensor activity							pg	2018-12-10T14:30:28Z					molecular_function											owl:Class	
GO:0009609	biolink:NamedThing	response to symbiotic bacterium	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a symbiotic bacterium, a bacterium living in close physical association with another organism.	tmpzr1t_l9r_go_relaxed.owl	response to symbiotic bacteria													biological_process											owl:Class	
GO:0009608	biolink:NamedThing	response to symbiont	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a symbiont, an organism living with an organism of a different species in close physical association. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	response of host to symbiont													biological_process											owl:Class	
GO:0033026	biolink:NamedThing	negative regulation of mast cell apoptotic process	Any process that stops, prevents, or reduces the frequency, rate, or extent of mast cell apoptotic process.	tmpzr1t_l9r_go_relaxed.owl	down regulation of mast cell apoptosis|inhibition of mast cell apoptosis|downregulation of mast cell apoptosis|down-regulation of mast cell apoptosis|negative regulation of mast cell apoptosis													biological_process											owl:Class	
GO:0002683	biolink:NamedThing	negative regulation of immune system process	Any process that stops, prevents, or reduces the frequency, rate, or extent of an immune system process.	tmpzr1t_l9r_go_relaxed.owl	downregulation of immune system process|down regulation of immune system process|inhibition of immune system process|down-regulation of immune system process													biological_process											owl:Class	
GO:0018490	biolink:NamedThing	4-hydroxyphenylpyruvate oxidase activity	Catalysis of the reaction: 2 (4-hydroxyphenyl)pyruvate + O(2) = 2 (4-hydroxyphenyl)acetate + 2 CO(2).	tmpzr1t_l9r_go_relaxed.owl	4-hydroxyphenylpyruvate:oxygen oxidoreductase (decarboxylating)				RHEA:17197|UM-BBD_reactionID:r0299|MetaCyc:1.2.3.13-RXN|KEGG_REACTION:R00042|EC:1.2.3.13									molecular_function											owl:Class	
GO:0002660	biolink:NamedThing	positive regulation of peripheral tolerance induction	Any process that activates or increases the frequency, rate, or extent of peripheral tolerance induction.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of peripheral tolerance induction|upregulation of peripheral tolerance induction|up regulation of peripheral tolerance induction|stimulation of peripheral tolerance induction|activation of peripheral tolerance induction													biological_process											owl:Class	
GO:0002654	biolink:NamedThing	positive regulation of tolerance induction dependent upon immune response	Any process that activates or increases the frequency, rate, or extent of tolerance induction dependent upon immune response.	tmpzr1t_l9r_go_relaxed.owl	up regulation of tolerance induction dependent upon immune response|activation of tolerance induction dependent upon immune response|upregulation of tolerance induction dependent upon immune response|positive regulation of immune response-dependent tolerance induction|up-regulation of tolerance induction dependent upon immune response|stimulation of tolerance induction dependent upon immune response													biological_process											owl:Class	
GO:0031644	biolink:NamedThing	regulation of nervous system process	Any process that modulates the frequency, rate or extent of a neurophysiological process, an organ system process carried out by any of the organs or tissues of the nervous system.	tmpzr1t_l9r_go_relaxed.owl	regulation of neurological system process|regulation of neurological process|regulation of neurophysiological process													biological_process											owl:Class	
GO:0044057	biolink:NamedThing	regulation of system process	Any process that modulates the frequency, rate or extent of a system process, a multicellular organismal process carried out by any of the organs or tissues in an organ system.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1902700	biolink:NamedThing	pentose catabolic process to butan-1-ol	The chemical reactions and pathways resulting in the breakdown of pentose to butan-1-ol.	tmpzr1t_l9r_go_relaxed.owl	pentose degradation to butan-1-ol|pentose catabolic process to butanol|pentose breakdown to butan-1-ol|pentose catabolic process to 1-butanol|pentose catabolism to butan-1-ol|solventogenesis							tb	2014-02-19T18:28:47Z			GO:1990290		biological_process											owl:Class	
GO:0071270	biolink:NamedThing	1-butanol metabolic process	The chemical reactions and pathways involving 1-butanol, an alkyl primary alcohol with the formula C4H10O.	tmpzr1t_l9r_go_relaxed.owl	1-butanol metabolism|butanol metabolic process|butan-1-ol metabolic process							mah	2009-12-10T10:23:11Z					biological_process											owl:Class	
GO:0019819	biolink:NamedThing	P1 peroxisome	A subform of peroxisome that corresponds to an intermediate in a peroxisome assembly pathway, which operates by conversion of peroxisomal subforms in the direction P1, P2 -> P3 -> P4 -> P5 -> P6. P1 peroxisomes are distinguished from the other subforms on the bases of buoyant density and protein content; they contain fewer peroxisomal proteins than the other subforms.	tmpzr1t_l9r_go_relaxed.owl	peroxisome vesicle					Note that this peroxisome assembly pathway is described in the yeast Yarrowia lipolytica. See also the cellular component terms 'P2 peroxisome ; GO:0019820', 'P3 peroxisome ; GO:0019821', 'P4 peroxisome ; GO:0019822', 'P5 peroxisome ; GO:0019823', and 'P6 peroxisome ; GO:0019824'.								cellular_component											owl:Class	
GO:0005777	biolink:NamedThing	peroxisome	A small organelle enclosed by a single membrane, and found in most eukaryotic cells. Contains peroxidases and other enzymes involved in a variety of metabolic processes including free radical detoxification, lipid catabolism and biosynthesis, and hydrogen peroxide metabolism.	tmpzr1t_l9r_go_relaxed.owl	peroxisomal|peroxisome vesicle				Wikipedia:Peroxisome|NIF_Subcellular:sao499555322							GO:0019818		cellular_component											owl:Class	
GO:0018309	biolink:NamedThing	protein-FMN linkage	The formation of a linkage between a protein amino acid and flavin mononucleotide (FMN).	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0034767	biolink:NamedThing	positive regulation of ion transmembrane transport	Any process that activates or increases the frequency, rate or extent of the directed movement of ions from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	stimulation of transmembrane ion transport|upregulation of transmembrane ion transport|activation of transmembrane ion transport|up-regulation of transmembrane ion transport|up regulation of transmembrane ion transport|positive regulation of ion membrane transport|positive regulation of transmembrane ion transport													biological_process											owl:Class	
GO:0043270	biolink:NamedThing	positive regulation of ion transport	Any process that activates or increases the frequency, rate or extent of the directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	stimulation of ion transport|up-regulation of ion transport|up regulation of ion transport|activation of ion transport|upregulation of ion transport													biological_process											owl:Class	
GO:1900835	biolink:NamedThing	negative regulation of emericellin biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of emericellin biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of emericellin biosynthetic process|downregulation of emericellin biosynthetic process|down regulation of emericellin biosynthetic process							di	2012-06-07T09:32:24Z					biological_process											owl:Class	
GO:1900377	biolink:NamedThing	negative regulation of secondary metabolite biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of secondary metabolite biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of secondary metabolite biosynthetic process|negative regulation of secondary metabolite biosynthesis|inhibition of secondary metabolite biosynthetic process|down regulation of secondary metabolite biosynthetic process|downregulation of secondary metabolite biosynthesis|downregulation of secondary metabolite biosynthetic process|down-regulation of secondary metabolite biosynthesis|inhibition of secondary metabolite biosynthesis|down regulation of secondary metabolite biosynthesis							di	2012-04-17T01:55:32Z					biological_process											owl:Class	
GO:0070949	biolink:NamedThing	regulation of neutrophil mediated killing of symbiont cell	Any process that modulates the rate, frequency or extent of neutrophil mediated killing of a symbiont cell, the directed killing of a symbiont target cell by a neutrophil.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-10-01T02:14:36Z					biological_process											owl:Class	
GO:0002831	biolink:NamedThing	regulation of response to biotic stimulus	Any process that modulates the frequency, rate, or extent of a response to biotic stimulus.	tmpzr1t_l9r_go_relaxed.owl						Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.								biological_process											owl:Class	
GO:1904480	biolink:NamedThing	positive regulation of intestinal absorption	Any process that activates or increases the frequency, rate or extent of intestinal absorption.	tmpzr1t_l9r_go_relaxed.owl	activation of intestinal absorption|upregulation of intestinal absorption|up regulation of intestinal absorption|up-regulation of intestinal absorption							rl	2015-07-13T15:59:00Z					biological_process											owl:Class	
GO:0060456	biolink:NamedThing	positive regulation of digestive system process	Any process that increases the frequency, rate or extent of a digestive system process, a physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0045666	biolink:NamedThing	positive regulation of neuron differentiation	Any process that activates or increases the frequency, rate or extent of neuron differentiation.	tmpzr1t_l9r_go_relaxed.owl	stimulation of neuron differentiation|up regulation of neuron differentiation|activation of neuron differentiation|upregulation of neuron differentiation|up-regulation of neuron differentiation													biological_process											owl:Class	
GO:0003674	biolink:NamedThing	molecular_function	A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs. These actions are described from two distinct but related perspectives: (1) biochemical activity, and (2) role as a component in a larger system/process.	tmpzr1t_l9r_go_relaxed.owl	molecular function					Note that, in addition to forming the root of the molecular function ontology, this term is recommended for use for the annotation of gene products whose molecular function is unknown. When this term is used for annotation, it indicates that no information was available about the molecular function of the gene product annotated as of the date the annotation was made; the evidence code 'no data' (ND), is used to indicate this. Despite its name, this is not a type of 'function' in the sense typically defined by upper ontologies such as Basic Formal Ontology (BFO). It is instead a BFO:process carried out by a single gene product or complex.						GO:0005554		molecular_function											owl:Class	
GO:1900512	biolink:NamedThing	regulation of starch utilization system complex assembly	Any process that modulates the frequency, rate or extent of starch utilization system complex assembly.	tmpzr1t_l9r_go_relaxed.owl	regulation of SUS complex assembly|regulation of assembly of starch utilization system complex							tt	2012-05-02T04:06:44Z					biological_process											owl:Class	
GO:0043254	biolink:NamedThing	regulation of protein-containing complex assembly	Any process that modulates the frequency, rate or extent of protein complex assembly.	tmpzr1t_l9r_go_relaxed.owl	regulation of protein complex assembly													biological_process											owl:Class	
GO:0102434	biolink:NamedThing	pterin-4alpha-carbinolamine dehydratase activity	Catalysis of the reaction: a 10-formyltetrahydrofolate-4a-carbinolamine = H2O + a 10-formyldihydrofolate.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-13908									molecular_function											owl:Class	
GO:0061099	biolink:NamedThing	negative regulation of protein tyrosine kinase activity	Any process that decreases the rate, frequency, or extent of protein tyrosine kinase activity.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-04-26T02:34:53Z					biological_process											owl:Class	
GO:0000414	biolink:NamedThing	regulation of histone H3-K36 methylation	Any process that modulates the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 36 of histone H3.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0051792	biolink:NamedThing	medium-chain fatty acid biosynthetic process	The chemical reactions and pathways resulting in the formation of any fatty acid with a chain length of between C6 and C12.	tmpzr1t_l9r_go_relaxed.owl	medium chain fatty acid biosynthesis|medium chain fatty acid biosynthetic process|medium-chain fatty acid biosynthesis|medium-chain fatty acid formation|medium-chain fatty acid anabolism|medium-chain fatty acid synthesis													biological_process											owl:Class	
GO:0006633	biolink:NamedThing	fatty acid biosynthetic process	The chemical reactions and pathways resulting in the formation of a fatty acid, any of the aliphatic monocarboxylic acids that can be liberated by hydrolysis from naturally occurring fats and oils. Fatty acids are predominantly straight-chain acids of 4 to 24 carbon atoms, which may be saturated or unsaturated; branched fatty acids and hydroxy fatty acids also occur, and very long chain acids of over 30 carbons are found in waxes.	tmpzr1t_l9r_go_relaxed.owl	fatty acid anabolism|fatty acid formation|fatty acid biosynthesis|fatty acid synthesis				MetaCyc:PWY-4381|Wikipedia:Fatty_acid_synthesis|MetaCyc:PWY-5156|MetaCyc:FASYN-INITIAL-PWY							GO:0000037		biological_process											owl:Class	
GO:1904664	biolink:NamedThing	negative regulation of N-terminal peptidyl-methionine acetylation	Any process that stops, prevents or reduces the frequency, rate or extent of N-terminal peptidyl-methionine acetylation.	tmpzr1t_l9r_go_relaxed.owl								vw	2015-09-07T19:18:56Z					biological_process											owl:Class	
GO:0034642	biolink:NamedThing	mitochondrion migration along actin filament	The directed movement of a mitochondrion along a microfilament, mediated by motor proteins.	tmpzr1t_l9r_go_relaxed.owl	mitochondrial migration, actin-mediated|mitochondrial migration along microfilament|mitochondrion migration along microfilament|mitochondrion transport along actin filament|mitochondrial migration along actin filament													biological_process											owl:Class	
GO:0099515	biolink:NamedThing	actin filament-based transport	The transport of organelles or other particles from one location in the cell to another along actin filaments.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-05-27T10:56:08Z					biological_process											owl:Class	
GO:0062038	biolink:NamedThing	positive regulation of pheromone response MAPK cascade	Any process that activates or increases the frequency, rate or extent of a pheromone response MAPK cascade.	tmpzr1t_l9r_go_relaxed.owl								dph	2018-05-01T13:00:56Z					biological_process											owl:Class	
GO:1904413	biolink:NamedThing	negative regulation of cardiac ventricle development	Any process that stops, prevents or reduces the frequency, rate or extent of cardiac ventricle development.	tmpzr1t_l9r_go_relaxed.owl	downregulation of cardiac ventricle development|inhibition of cardiac ventricle development|down regulation of cardiac ventricle development|down-regulation of cardiac ventricle development							sl	2015-06-25T19:52:21Z					biological_process											owl:Class	
GO:0031279	biolink:NamedThing	regulation of cyclase activity	Any process that modulates the frequency, rate or extent of cyclase activity.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0022870	biolink:NamedThing	protein-N(PI)-phosphohistidine-mannose phosphotransferase system transporter activity	Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + mannose(out) = protein histidine + mannose phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.	tmpzr1t_l9r_go_relaxed.owl	mannose PTS transporter activity													molecular_function											owl:Class	
GO:0015578	biolink:NamedThing	mannose transmembrane transporter activity	Enables the transfer of mannose from one side of a membrane to the other. Mannose is the aldohexose manno-hexose, the C-2 epimer of glucose. The D-(+)-form is widely distributed in mannans and hemicelluloses and is of major importance in the core oligosaccharide of N-linked oligosaccharides of glycoproteins.	tmpzr1t_l9r_go_relaxed.owl	mannose permease activity											GO:0015589		molecular_function											owl:Class	
GO:0044217	biolink:NamedThing	other organism part	Any constituent part of a secondary organism with which the first organism is interacting.	tmpzr1t_l9r_go_relaxed.owl						Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.		jl	2009-11-12T01:18:21Z					cellular_component											owl:Class	
GO:0019990	biolink:NamedThing	pteridine catabolic process	The chemical reactions and pathways resulting in the breakdown of pteridine, pyrazino(2,3-dipyrimidine), the parent structure of pterins and the pteroyl group.	tmpzr1t_l9r_go_relaxed.owl	pteridine breakdown|pteridine degradation|pteridine catabolism													biological_process											owl:Class	
GO:0042560	biolink:NamedThing	pteridine-containing compound catabolic process	The chemical reactions and pathways resulting in the breakdown of any compound containing pteridine (pyrazino(2,3-dipyrimidine)), e.g. pteroic acid, xanthopterin and folic acid.	tmpzr1t_l9r_go_relaxed.owl	pteridine and derivative catabolic process|pterin catabolic process|pteridine-containing compound degradation|pteridine-containing compound catabolism|pterin catabolism|pteridine and derivative catabolism|pteridine-containing compound breakdown													biological_process											owl:Class	
GO:0001097	biolink:NamedThing	TFIIH-class transcription factor complex binding	Binding to a general RNA polymerase II transcription factor belonging to the TFIIH complex, one of the factors involved in formation of the preinitiation complex (PIC) by RNA polymerase II.	tmpzr1t_l9r_go_relaxed.owl	TFIIH-class transcription factor binding							krc	2010-10-28T02:51:41Z					molecular_function											owl:Class	
GO:0001091	biolink:NamedThing	RNA polymerase II general transcription initiation factor binding	Binding to a basal RNA polymerase II transcription factor, any of the factors involved in formation of the preinitiation complex (PIC) by RNA polymerase II and defined as a basal or general transcription factor.	tmpzr1t_l9r_go_relaxed.owl	RNA polymerase II basal transcription factor binding							krc	2010-10-28T02:30:02Z					molecular_function											owl:Class	
GO:1904486	biolink:NamedThing	response to 17alpha-ethynylestradiol	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 17alpha-ethynylestradiol stimulus.	tmpzr1t_l9r_go_relaxed.owl								mr	2015-07-15T22:31:36Z					biological_process											owl:Class	
GO:1902637	biolink:NamedThing	neural crest cell differentiation involved in thymus development	Any neural crest cell differentiation that is involved in thymus development.	tmpzr1t_l9r_go_relaxed.owl								pr	2014-01-21T10:03:20Z					biological_process											owl:Class	
GO:0014033	biolink:NamedThing	neural crest cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a neural crest cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1990901	biolink:NamedThing	old cell pole	The cell pole distal from the most recent cell division.	tmpzr1t_l9r_go_relaxed.owl								pr	2015-11-17T16:42:16Z					cellular_component											owl:Class	
GO:0060187	biolink:NamedThing	cell pole	Either of two different areas at opposite ends of an axis of a cell.	tmpzr1t_l9r_go_relaxed.owl						Note that this term differs from 'cell tip ; GO:0051286' in that it is applicable to a broad range of cell shapes including spherical and cuboidal.								cellular_component											owl:Class	
GO:0034064	biolink:NamedThing	Tor2-Mei2-Ste11 complex	A protein complex that contains the transcription factor Ste11 and the RNA binding protein Mei2; involved in regulation of conjugation in fission yeast.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0075019	biolink:NamedThing	negative regulation of appressorium formation	Any process that stops, prevents, or reduces the frequency, rate or extent of symbiont appressorium formation.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of appressorium formation on or near host					Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products from the symbiont involved in this process.								biological_process											owl:Class	
GO:0080154	biolink:NamedThing	regulation of fertilization	Any process that modulates the rate, frequency or extent of fertilization. Fertilization is the union of gametes of opposite sexes during the process of sexual reproduction to form a zygote. It involves the fusion of the gametic nuclei (karyogamy) and cytoplasm (plasmogamy).	tmpzr1t_l9r_go_relaxed.owl								dhl	2010-09-01T03:44:27Z					biological_process											owl:Class	
GO:0032943	biolink:NamedThing	mononuclear cell proliferation	The expansion of a mononuclear cell population by cell division. A mononuclear cell is a leukocyte with a single non-segmented nucleus in the mature form.	tmpzr1t_l9r_go_relaxed.owl	PBMC proliferation|peripheral blood mononuclear cell proliferation													biological_process											owl:Class	
GO:0070661	biolink:NamedThing	leukocyte proliferation	The expansion of a leukocyte population by cell division.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-05-28T05:25:28Z					biological_process											owl:Class	
GO:0090086	biolink:NamedThing	negative regulation of protein deubiquitination	Any process that decreases the frequency, rate or extent of protein deubiquitination. Protein deubiquitination is the removal of one or more ubiquitin groups from a protein.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-10-23T11:18:06Z					biological_process											owl:Class	
GO:0090085	biolink:NamedThing	regulation of protein deubiquitination	Any process that modulates the frequency, rate or extent of protein deubiquitination. Protein deubiquitination is the removal of one or more ubiquitin groups from a protein.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-10-23T11:16:32Z					biological_process											owl:Class	
GO:0034223	biolink:NamedThing	regulation of ascospore wall chitin biosynthetic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of ascospore wall chitin.	tmpzr1t_l9r_go_relaxed.owl	regulation of ascospore wall chitin synthesis|regulation of ascospore wall chitin formation|regulation of ascospore wall chitin anabolism|regulation of ascospore wall chitin biosynthesis													biological_process											owl:Class	
GO:0032995	biolink:NamedThing	regulation of fungal-type cell wall biogenesis	Any process that modulates the process in which a cell wall is synthesized, aggregates, and bonds together. The fungal-type cell wall contains beta-glucan and may contain chitin.	tmpzr1t_l9r_go_relaxed.owl	regulation of chitin- and beta-glucan-containing cell wall biogenesis													biological_process											owl:Class	
GO:0070686	biolink:NamedThing	macropinocytic cup membrane	The portion of the plasma membrane surrounding a macropinocytic cup.	tmpzr1t_l9r_go_relaxed.owl	crown membrane							mah	2009-06-03T10:52:25Z					cellular_component											owl:Class	
GO:0031253	biolink:NamedThing	cell projection membrane	The portion of the plasma membrane surrounding a plasma membrane bounded cell surface projection.	tmpzr1t_l9r_go_relaxed.owl	membrane extension|membrane projection													cellular_component											owl:Class	
GO:0042082	biolink:NamedThing	GSI anchor biosynthetic process	The chemical reactions and pathways resulting in the formation of a glycosylsphingolipidinositol (GSI) anchor that attaches some membrane proteins to the lipid bilayer of the cell membrane. The sphingolipid group is linked, via the C-6 hydroxyl residue of inositol to a carbohydrate chain which is itself linked to the protein via a ethanolamine phosphate group, its amino group forming an amide linkage with the C-terminal carboxyl of the protein. Some GSI anchors have variants on this canonical linkage.	tmpzr1t_l9r_go_relaxed.owl	GSI anchor formation|GPI/GSI anchor biosynthetic process|GSI anchor biosynthesis|GSI anchor anabolism|GSI anchor synthesis|GPI/GSI anchor biosynthesis													biological_process											owl:Class	
GO:0042081	biolink:NamedThing	GSI anchor metabolic process	The chemical reactions and pathways involving glycosylsphingolipidinositol (GSI) anchors, which attach membrane proteins to the lipid bilayer of the cell membrane.	tmpzr1t_l9r_go_relaxed.owl	GSI anchor metabolism|GPI/GSI anchor metabolic process|GPI/GSI anchor metabolism													biological_process											owl:Class	
GO:2000539	biolink:NamedThing	regulation of protein geranylgeranylation	Any process that modulates the frequency, rate or extent of protein geranylgeranylation.	tmpzr1t_l9r_go_relaxed.owl	regulation of protein amino acid geranylgeranylation|regulation of C-terminal protein geranylgeranylation							tb	2011-03-29T06:23:05Z					biological_process											owl:Class	
GO:0030448	biolink:NamedThing	hyphal growth	Growth of fungi as threadlike, tubular structures that may contain multiple nuclei and may or may not be divided internally by septa, or cross-walls.	tmpzr1t_l9r_go_relaxed.owl	formation of symbiont invasive hypha within host during symbiotic interaction|formation of symbiont invasive hypha within host|formation of symbiont invasive hypha in host|symbiont invasive hypha formation within host|invasive hyphal growth	https://github.com/geneontology/go-ontology/issues/19013										GO:0075061		biological_process											owl:Class	
GO:0030447	biolink:NamedThing	filamentous growth	The process in which a multicellular organism, a unicellular organism or a group of unicellular organisms grow in a threadlike, filamentous shape.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0002866	biolink:NamedThing	positive regulation of acute inflammatory response to antigenic stimulus	Any process that activates or increases the frequency, rate, or extent of an acute inflammatory response to an antigenic stimulus.	tmpzr1t_l9r_go_relaxed.owl	up regulation of acute inflammatory response to antigenic stimulus|up-regulation of acute inflammatory response to antigenic stimulus|stimulation of acute inflammatory response to antigenic stimulus|upregulation of acute inflammatory response to antigenic stimulus|activation of acute inflammatory response to antigenic stimulus													biological_process											owl:Class	
GO:0002863	biolink:NamedThing	positive regulation of inflammatory response to antigenic stimulus	Any process that activates or increases the frequency, rate, or extent of an inflammatory response to an antigenic stimulus.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of inflammatory response to antigenic stimulus|stimulation of inflammatory response to antigenic stimulus|up regulation of inflammatory response to antigenic stimulus|activation of inflammatory response to antigenic stimulus|upregulation of inflammatory response to antigenic stimulus													biological_process											owl:Class	
GO:0005851	biolink:NamedThing	eukaryotic translation initiation factor 2B complex	A multisubunit guanine nucleotide exchange factor which catalyzes the exchange of GDP bound to initiation factor eIF2 for GTP, generating active eIF2-GTP. In humans, it is composed of five subunits, alpha, beta, delta, gamma and epsilon.	tmpzr1t_l9r_go_relaxed.owl	eIF-2B|eif2B													cellular_component											owl:Class	
GO:0080130	biolink:NamedThing	L-phenylalanine:2-oxoglutarate aminotransferase activity	Catalysis of the reaction: L-phenylalanine + 2-oxoglutarate = phenylpyruvate + L-glutamate.	tmpzr1t_l9r_go_relaxed.owl	L-phenylalanine:alpha-ketoglutarate aminotransferase activity				MetaCyc:RXN-10814|MetaCyc:PHEAMINOTRANS-RXN|KEGG_REACTION:R00694|RHEA:25152|EC:2.6.1.57	This reaction falls within the larger set of reactions associated with EC:2.6.1.57 and several other EC numbers (See BRENDA:http://www.brenda-enzymes.org/php/result_flat.php4?ecno=2.6.1.57).		dhl	2009-04-29T03:42:47Z					molecular_function											owl:Class	
GO:0070546	biolink:NamedThing	L-phenylalanine aminotransferase activity	Catalysis of the transfer of an amino group from L-phenylalanine to an acceptor, usually a 2-oxo acid.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0106256	biolink:NamedThing	hydroperoxy icosatetraenoate dehydratase activity	A hydroperoxy icosatetraenoate <=> an oxoicosatetraenoate + H(2)O.	tmpzr1t_l9r_go_relaxed.owl					EC:4.2.1.152|RHEA:55556			hjd	2020-03-20T14:40:16Z					molecular_function											owl:Class	
GO:0044249	biolink:NamedThing	cellular biosynthetic process	The chemical reactions and pathways resulting in the formation of substances, carried out by individual cells.	tmpzr1t_l9r_go_relaxed.owl	cellular biosynthesis|cellular anabolism|cellular formation|cellular synthesis													biological_process											owl:Class	
GO:1905330	biolink:NamedThing	regulation of morphogenesis of an epithelium	Any process that modulates the frequency, rate or extent of morphogenesis of an epithelium.	tmpzr1t_l9r_go_relaxed.owl	regulation of epithelium morphogenesis					An example of this is MMRN2 in human (Q9H8L6) in PMID:25745997 (inferred from direct assay).		bhm	2016-07-22T07:13:49Z					biological_process											owl:Class	
GO:1902760	biolink:NamedThing	Mo(VI)-molybdopterin cytosine dinucleotide biosynthetic process	The chemical reactions and pathways resulting in the formation of Mo(VI)-molybdopterin cytosine dinucleotide.	tmpzr1t_l9r_go_relaxed.owl	Mo-molybdopterin-cytosine-dinucleotide cofactor biosynthetic process|Mo(VI)-molybdopterin cytosine dinucleotide biosynthesis|Mo(VI)-molybdopterin cytosine dinucleotide synthesis|Mo(VI)-molybdopterin cytosine dinucleotide formation|Mo(VI)-molybdopterin cytosine dinucleotide anabolism				MetaCyc:PWY-6476			dph	2014-03-06T14:00:43Z			GO:0061601		biological_process											owl:Class	
GO:0006777	biolink:NamedThing	Mo-molybdopterin cofactor biosynthetic process	The chemical reactions and pathways resulting in the formation of the Mo-molybdopterin cofactor, essential for the catalytic activity of some enzymes. The cofactor consists of a mononuclear molybdenum (Mo) ion coordinated by one or two molybdopterin ligands.	tmpzr1t_l9r_go_relaxed.owl	Mo-molybdopterin cofactor formation|Moco biosynthetic process|Mo-molybdopterin cofactor anabolism|Mo-molybdopterin cofactor synthesis|Mo-molybdopterin cofactor biosynthesis|Moco biosynthesis|molybdenum cofactor biosynthetic process				MetaCyc:PWY-6823									biological_process											owl:Class	
GO:0061425	biolink:NamedThing	positive regulation of ethanol catabolic process by positive regulation of transcription from RNA polymerase II promoter	Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter and activates or increases the frequency, rate or extent of an ethanol catabolic process.	tmpzr1t_l9r_go_relaxed.owl								dph	2012-02-02T01:12:36Z					biological_process											owl:Class	
GO:1900066	biolink:NamedThing	positive regulation of ethanol catabolic process	Any process that activates or increases the frequency, rate or extent of ethanol catabolic process.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of ethanol catabolism|upregulation of ethanol catabolism|up-regulation of ethanol catabolism|up-regulation of ethanol catabolic process|up regulation of ethanol catabolic process|positive regulation of ethanol breakdown|upregulation of ethanol catabolic process|activation of ethanol catabolism|activation of ethanol degradation|activation of ethanol breakdown|activation of ethanol catabolic process|upregulation of ethanol breakdown|up regulation of ethanol catabolism|up regulation of ethanol breakdown|upregulation of ethanol degradation|up-regulation of ethanol breakdown|up-regulation of ethanol degradation|up regulation of ethanol degradation|positive regulation of ethanol degradation							dph	2012-01-26T01:51:44Z					biological_process											owl:Class	
GO:0071803	biolink:NamedThing	positive regulation of podosome assembly	Any process that activates or increases the rate or extent of podosome assembly.	tmpzr1t_l9r_go_relaxed.owl	stimulation of podosome assembly|activation of podosome assembly|up regulation of podosome assembly|up-regulation of podosome assembly|upregulation of podosome assembly							mah	2010-09-03T01:50:50Z					biological_process											owl:Class	
GO:0099551	biolink:NamedThing	trans-synaptic signaling by neuropeptide, modulating synaptic transmission	Cell-cell signaling between presynapse and postsynapse, via the vesicular release and reception of neuropeptide molecules, that modulates the synaptic transmission properties of the synapse.	tmpzr1t_l9r_go_relaxed.owl						Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.								biological_process											owl:Class	
GO:0045040	biolink:NamedThing	protein insertion into mitochondrial outer membrane	The process comprising the insertion of proteins from outside the organelle into the mitochondrial outer membrane, mediated by large outer membrane translocase complexes.	tmpzr1t_l9r_go_relaxed.owl	mitochondrial outer membrane protein import|protein import into mitochondrial outer membrane|protein transport into mitochondrial outer membrane													biological_process											owl:Class	
GO:0051204	biolink:NamedThing	protein insertion into mitochondrial membrane	The process that results in the incorporation of a protein into a mitochondrial membrane.	tmpzr1t_l9r_go_relaxed.owl	integral mitochondrial membrane protein positioning|protein insertion into mitochondrion membrane|localization of protein in mitochondrial membrane|integral mitochondrial membrane protein localization|protein-mitochondrion membrane insertion|positioning of protein in mitochondrial membrane|protein-mitochondrial membrane insertion	https://github.com/geneontology/go-ontology/issues/15800												biological_process											owl:Class	
GO:0034355	biolink:NamedThing	NAD salvage	Any process that generates nicotinamide adenine dinucleotide (NAD) from derivatives of it, without de novo synthesis; salvage is usually from the degradation products nicotinic acid (Na) and nicotinamide (Nam).	tmpzr1t_l9r_go_relaxed.owl	NAD salvage pathway													biological_process											owl:Class	
GO:0019365	biolink:NamedThing	pyridine nucleotide salvage	Any process that generates a pyridine nucleotide, a nucleotide characterized by a pyridine derivative as a nitrogen base, from derivatives of them without de novo synthesis.	tmpzr1t_l9r_go_relaxed.owl	pyridine nucleotide cycling													biological_process											owl:Class	
GO:1900076	biolink:NamedThing	regulation of cellular response to insulin stimulus	Any process that modulates the frequency, rate or extent of cellular response to insulin stimulus.	tmpzr1t_l9r_go_relaxed.owl								yaf	2012-01-31T11:22:22Z					biological_process											owl:Class	
GO:0031654	biolink:NamedThing	regulation of heat dissipation	Any process that modulates the rate or extent of heat dissipation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0051239	biolink:NamedThing	regulation of multicellular organismal process	Any process that modulates the frequency, rate or extent of a multicellular organismal process, the processes pertinent to the function of a multicellular organism above the cellular level; includes the integrated processes of tissues and organs.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1902214	biolink:NamedThing	regulation of interleukin-4-mediated signaling pathway	Any process that modulates the frequency, rate or extent of interleukin-4-mediated signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	regulation of interleukin-4-mediated signalling pathway|regulation of IL-4-mediated signaling pathway							lb	2013-06-12T12:53:09Z					biological_process											owl:Class	
GO:0048021	biolink:NamedThing	regulation of melanin biosynthetic process	Any process that alters the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of melanin.	tmpzr1t_l9r_go_relaxed.owl	regulation of melanin anabolism|regulation of melanin biosynthesis|regulation of melanin synthesis|regulation of melanin formation													biological_process											owl:Class	
GO:0032270	biolink:NamedThing	positive regulation of cellular protein metabolic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a protein, occurring at the level of an individual cell.	tmpzr1t_l9r_go_relaxed.owl	upregulation of cellular protein metabolic process|up-regulation of cellular protein metabolic process|up regulation of cellular protein metabolic process|positive regulation of cellular protein metabolism|activation of cellular protein metabolic process|stimulation of cellular protein metabolic process													biological_process											owl:Class	
GO:0031325	biolink:NamedThing	positive regulation of cellular metabolic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of cellular metabolism|upregulation of cellular metabolic process|up regulation of cellular metabolic process|activation of cellular metabolic process|up-regulation of cellular metabolic process|stimulation of cellular metabolic process													biological_process											owl:Class	
GO:0044477	biolink:NamedThing	envenomation resulting in negative regulation of platelet aggregation in other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant stopping, prevention or reduction in the frequency, rate or extent of platelet aggregation in the bitten organism.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-01-19T02:36:44Z					biological_process											owl:Class	
GO:0035738	biolink:NamedThing	envenomation resulting in modulation of process in other organism	The process which begins with venom being forced into an organism by the bite or sting of another organism, and ends with the manifestation of some change or damage to the bitten organism.	tmpzr1t_l9r_go_relaxed.owl	envenomation resulting in modification of morphology or physiology of other organism	https://github.com/geneontology/go-ontology/issues/18605						bf	2011-03-17T10:59:27Z					biological_process											owl:Class	
GO:0046793	biolink:NamedThing	induction by virus of phosphorylation of host RNA polymerase II	Any process in which a virus activates the frequency, rate or extent of phosphorylation of host RNA polymerase II.	tmpzr1t_l9r_go_relaxed.owl	virus-induced modification of host RNA polymerase II|induction by virus of modification of host RNA polymerase II													biological_process											owl:Class	
GO:0039614	biolink:NamedThing	induction by virus of host protein phosphorylation	Any process in which a virus activates or increases the frequency, rate or extent of phosphorylation of viral or host proteins in a host.	tmpzr1t_l9r_go_relaxed.owl								bf	2012-07-06T11:15:56Z					biological_process											owl:Class	
GO:1903147	biolink:NamedThing	negative regulation of autophagy of mitochondrion	Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrion degradation by autophagy.	tmpzr1t_l9r_go_relaxed.owl	inhibition of mitochondrion degradation|down regulation of mitochondrion degradation|downregulation of mitochondrion degradation|inhibition of mitophagy|down-regulation of mitochondrion degradation|down regulation of mitochondrial degradation|down-regulation of mitophagy							bf	2014-07-09T08:23:58Z					biological_process											owl:Class	
GO:0050925	biolink:NamedThing	negative regulation of negative chemotaxis	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a motile cell or organism towards a lower concentration in a concentration gradient of a specific chemical.	tmpzr1t_l9r_go_relaxed.owl	inhibition of negative chemotaxis|downregulation of negative chemotaxis|down regulation of negative chemotaxis|down-regulation of negative chemotaxis													biological_process											owl:Class	
GO:0050923	biolink:NamedThing	regulation of negative chemotaxis	Any process that modulates the frequency, rate or extent of the directed movement of a motile cell or organism towards a lower concentration in a concentration gradient of a specific chemical.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1904449	biolink:NamedThing	negative regulation of aspartate secretion	Any process that stops, prevents or reduces the frequency, rate or extent of aspartate secretion.	tmpzr1t_l9r_go_relaxed.owl	inhibition of aspartate secretion|downregulation of aspartate secretion|down regulation of aspartate secretion|down-regulation of aspartate secretion							sl	2015-07-07T20:57:04Z					biological_process											owl:Class	
GO:0031147	biolink:NamedThing	1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one metabolic process	The chemical reactions and pathways involving 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one, also known as DIF-1, differentiation-inducing factor-1. DIF-1 is a secreted chlorinated molecule that controls cell fate during development of Dictyostelium cells.	tmpzr1t_l9r_go_relaxed.owl	1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one metabolism|DIF-1 metabolic process|DIF-1 metabolism													biological_process											owl:Class	
GO:0034051	biolink:NamedThing	negative regulation of plant-type hypersensitive response	Any process that stops, prevents, or reduces the frequency, rate or extent of the hypersensitive response in a plant.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of HR|negative regulation of HR-PCD|downregulation of plant-type hypersensitive response|negative regulation of plant hypersensitive response|down regulation of plant-type hypersensitive response|down-regulation of plant-type hypersensitive response|inhibition of plant-type hypersensitive response													biological_process											owl:Class	
GO:0010363	biolink:NamedThing	regulation of plant-type hypersensitive response	Any endogenous process that modulates the frequency, rate or extent of the plant hypersensitive response.	tmpzr1t_l9r_go_relaxed.owl	regulation of HR|regulation of HR-PCD|regulation of plant hypersensitive response					Note that term is to be used to annotate gene products in the plant. To annotate genes in a symbiont, consider the biological process term 'modulation by symbiont of host programmed cell death ; GO:0052040'.								biological_process											owl:Class	
GO:1904848	biolink:NamedThing	negative regulation of cell chemotaxis to fibroblast growth factor	Any process that stops, prevents or reduces the frequency, rate or extent of cell chemotaxis to fibroblast growth factor.	tmpzr1t_l9r_go_relaxed.owl	downregulation of cell chemotaxis to fibroblast growth factor|down regulation of cell chemotaxis to fibroblast growth factor|inhibition of cell chemotaxis to fibroblast growth factor|down-regulation of cell chemotaxis to fibroblast growth factor							rph	2015-12-10T12:04:08Z					biological_process											owl:Class	
GO:0090288	biolink:NamedThing	negative regulation of cellular response to growth factor stimulus	Any process that decreases the rate, frequency, or extent of a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth factor stimulus.	tmpzr1t_l9r_go_relaxed.owl								tb	2010-02-18T03:01:25Z					biological_process											owl:Class	
GO:0044065	biolink:NamedThing	regulation of respiratory system process	Any process that modulates the frequency, rate or extent of a respiratory system process, an organ system process carried out by any of the organs or tissues of the respiratory system.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0102281	biolink:NamedThing	formylaminopyrimidine deformylase activity	Catalysis of the reaction: formylaminopyrimidine + H2O <=> 4-amino-5-ammoniomethyl-2-methylpyrimidine + formate.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-12612									molecular_function											owl:Class	
GO:0016811	biolink:NamedThing	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a linear amide.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-9673053|Reactome:R-HSA-9673054|EC:3.5.1.-									molecular_function											owl:Class	
GO:0007553	biolink:NamedThing	regulation of ecdysteroid metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving ecdysteroids, a group of polyhydroxylated ketosteroids which initiate post-embryonic development, including the metamorphosis of immature forms and the development of the reproductive system and the maturation of oocytes in adult females.	tmpzr1t_l9r_go_relaxed.owl	regulation of ecdysteroid metabolism													biological_process											owl:Class	
GO:0032350	biolink:NamedThing	regulation of hormone metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving any hormone.	tmpzr1t_l9r_go_relaxed.owl	regulation of hormone metabolism													biological_process											owl:Class	
GO:1903096	biolink:NamedThing	protein localization to meiotic spindle midzone	A process in which a protein is transported to, or maintained in, a location within a meiotic spindle midzone.	tmpzr1t_l9r_go_relaxed.owl	protein localisation in meiotic spindle midzone|protein localisation to meiotic spindle midzone|protein localization in meiotic spindle midzone							kmv	2014-06-03T16:06:22Z					biological_process											owl:Class	
GO:1905359	biolink:NamedThing	protein localization to meiotic spindle	A process in which a protein is transported to, or maintained in, a location within a meiotic spindle.	tmpzr1t_l9r_go_relaxed.owl	protein localisation to meiotic spindle							mah	2016-08-10T14:49:03Z					biological_process											owl:Class	
GO:2000396	biolink:NamedThing	negative regulation of ubiquitin-dependent endocytosis	Any process that stops, prevents or reduces the frequency, rate or extent of ubiquitin-dependent endocytosis.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of ubiquitin-mediated endocytosis							mah	2011-02-22T11:25:21Z					biological_process											owl:Class	
GO:0045806	biolink:NamedThing	negative regulation of endocytosis	Any process that stops, prevents, or reduces the frequency, rate or extent of endocytosis.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of endocytosis|inhibition of endocytosis|downregulation of endocytosis|down regulation of endocytosis													biological_process											owl:Class	
GO:2000048	biolink:NamedThing	negative regulation of cell-cell adhesion mediated by cadherin	Any process that stops, prevents, or reduces the frequency, rate or extent of cell-cell adhesion mediated by cadherin.	tmpzr1t_l9r_go_relaxed.owl								jl	2010-08-20T12:56:51Z					biological_process											owl:Class	
GO:0061043	biolink:NamedThing	regulation of vascular wound healing	Any process that modulates the rate, frequency, or extent of blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels and contribute to the series of events that restore integrity to damaged vasculature.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-02-25T10:21:59Z					biological_process											owl:Class	
GO:0045765	biolink:NamedThing	regulation of angiogenesis	Any process that modulates the frequency, rate or extent of angiogenesis.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:2001105	biolink:NamedThing	maltoheptaose transport	The directed movement of a maltoheptaoseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl								jl	2011-09-21T02:31:22Z					biological_process											owl:Class	
GO:2001104	biolink:NamedThing	heptasaccharide transport	The directed movement of a heptasaccharideacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl								jl	2011-09-21T02:29:58Z					biological_process											owl:Class	
GO:0015859	biolink:NamedThing	intracellular nucleoside transport	The directed movement of a nucleoside, a nucleobase linked to either beta-D-ribofuranose (ribonucleoside) or 2-deoxy-beta-D-ribofuranose, (a deoxyribonucleotide), within a cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0015858	biolink:NamedThing	nucleoside transport	The directed movement of a nucleoside, a nucleobase linked to either beta-D-ribofuranose (ribonucleoside) or 2-deoxy-beta-D-ribofuranose, (a deoxyribonucleotide), into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0043377	biolink:NamedThing	negative regulation of CD8-positive, alpha-beta T cell differentiation	Any process that stops, prevents, or reduces the rate of CD8-positive, alpha-beta T cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of CD8-positive, alpha-beta T cell development|downregulation of CD8-positive, alpha-beta T cell differentiation|down-regulation of CD8-positive, alpha-beta T cell differentiation|negative regulation of CD8-positive, alpha beta T-lymphocyte differentiation|negative regulation of CD8-positive T-cell differentiation|negative regulation of CD8-positive, alpha beta T-cell differentiation|negative regulation of CD8-positive T lymphocyte differentiation|down regulation of CD8-positive, alpha-beta T cell differentiation|negative regulation of CD8-positive, alpha beta T lymphocyte differentiation|inhibition of CD8-positive, alpha-beta T cell differentiation|negative regulation of CD8-positive T-lymphocyte differentiation					Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.								biological_process											owl:Class	
GO:1905388	biolink:NamedThing	cellular response to beta-carotene	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a beta-carotene stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to beta,beta-carotene							sl	2016-08-18T16:18:31Z					biological_process											owl:Class	
GO:1905387	biolink:NamedThing	response to beta-carotene	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a beta-carotene stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to beta,beta-carotene							sl	2016-08-18T16:18:24Z					biological_process											owl:Class	
GO:0010712	biolink:NamedThing	regulation of collagen metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the metabolism of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals.	tmpzr1t_l9r_go_relaxed.owl	regulation of collagen metabolism													biological_process											owl:Class	
GO:0003128	biolink:NamedThing	heart field specification	The process that results in the delineation of a specific region of the lateral mesoderm into the area in which the heart will develop.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-09-22T02:56:05Z					biological_process											owl:Class	
GO:0010092	biolink:NamedThing	specification of animal organ identity	The regionalization process in which the identity of an animal organ primordium is specified. Identity is considered to be the aggregate of characteristics by which a structure is recognized.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0030711	biolink:NamedThing	positive regulation of border follicle cell delamination	Any process that increases the frequency, rate or extent of border cell delamination.	tmpzr1t_l9r_go_relaxed.owl	stimulation of border follicle cell delamination|up regulation of border follicle cell delamination|up-regulation of border follicle cell delamination|positive regulation of border cell delamination|activation of border follicle cell delamination|upregulation of border follicle cell delamination													biological_process											owl:Class	
GO:0021582	biolink:NamedThing	medulla oblongata maturation	A developmental process, independent of morphogenetic (shape) change, that is required for the medulla oblongata to attain its fully functional state. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate.	tmpzr1t_l9r_go_relaxed.owl	myelencephalon maturation|medulla maturation													biological_process											owl:Class	
GO:0071695	biolink:NamedThing	anatomical structure maturation	A developmental process, independent of morphogenetic (shape) change, that is required for an anatomical structure to attain its fully functional state.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-03-02T11:43:38Z					biological_process											owl:Class	
GO:0050814	biolink:NamedThing	epothilone biosynthetic process	The chemical reactions and pathways resulting in the formation of epothilone, a drug obtained from the myxobacteria Sporangium cellulosum that interferes with cell division. Some epothilones are being studied as treatments for cancer.	tmpzr1t_l9r_go_relaxed.owl	epothilone anabolism|epothilone biosynthesis|epothilone synthesis|epothilone formation													biological_process											owl:Class	
GO:0097634	biolink:NamedThing	integral component of phagophore assembly site membrane	The component of the phagophore assembly site membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.	tmpzr1t_l9r_go_relaxed.owl	integral to phagophore assembly site membrane|phagophore assembly site integral membrane protein													cellular_component											owl:Class	
GO:0097633	biolink:NamedThing	intrinsic component of phagophore assembly site membrane	The component of the phagophore assembly site membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.	tmpzr1t_l9r_go_relaxed.owl	intrinsic to phagophore assembly site membrane													cellular_component											owl:Class	
GO:1900664	biolink:NamedThing	regulation of emodin biosynthetic process	Any process that modulates the frequency, rate or extent of emodin biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of emodin anabolism|regulation of emodin synthesis|regulation of emodin formation|regulation of emodin biosynthesis							di	2012-05-22T04:14:36Z					biological_process											owl:Class	
GO:1900376	biolink:NamedThing	regulation of secondary metabolite biosynthetic process	Any process that modulates the frequency, rate or extent of secondary metabolite biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of secondary metabolite biosynthesis							di	2012-04-17T01:55:23Z					biological_process											owl:Class	
GO:0019332	biolink:NamedThing	aerobic respiration, using nitrite as electron donor	The oxidation of nitrite (NO2) to nitrate (NO3), using oxygen (O2) as the electron acceptor. Nitrite oxidation is the final step in nitrification, the oxidation of ammonia to nitrate, and nitrite oxidoreductase (NOR) is the key enzyme complex that catalyzes the conversion of nitrite to nitrate in nitrite oxidizing species.	tmpzr1t_l9r_go_relaxed.owl	nitrite oxidation				MetaCyc:P282-PWY									biological_process											owl:Class	
GO:0015975	biolink:NamedThing	energy derivation by oxidation of reduced inorganic compounds	The chemical reactions and pathways by which a cell derives energy from inorganic compounds; results in the oxidation of the compounds from which energy is released.	tmpzr1t_l9r_go_relaxed.owl	chemolithotrophie|lithotrophy|chemolithotrophy				Wikipedia:Lithotrophy									biological_process											owl:Class	
GO:0098501	biolink:NamedThing	polynucleotide dephosphorylation	The process of removing one or more phosphate groups from a polynucleotide.	tmpzr1t_l9r_go_relaxed.owl								dos	2013-09-18T14:49:10Z					biological_process											owl:Class	
GO:0016311	biolink:NamedThing	dephosphorylation	The process of removing one or more phosphoric (ester or anhydride) residues from a molecule.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Dephosphorylation									biological_process											owl:Class	
GO:1905652	biolink:NamedThing	negative regulation of artery morphogenesis	Any process that stops, prevents or reduces the frequency, rate or extent of artery morphogenesis.	tmpzr1t_l9r_go_relaxed.owl	inhibition of artery morphogenesis|downregulation of arterial morphogenesis|down-regulation of artery morphogenesis|downregulation of arteriogenesis|inhibition of arteriogenesis|negative regulation of arterial morphogenesis|down regulation of arteriogenesis|down-regulation of arteriogenesis|negative regulation of arteriogenesis|down regulation of artery morphogenesis|inhibition of arterial morphogenesis|down regulation of arterial morphogenesis|down-regulation of arterial morphogenesis|downregulation of artery morphogenesis							rph	2016-11-09T12:19:53Z					biological_process											owl:Class	
GO:1905651	biolink:NamedThing	regulation of artery morphogenesis	Any process that modulates the frequency, rate or extent of artery morphogenesis.	tmpzr1t_l9r_go_relaxed.owl	regulation of arteriogenesis|regulation of arterial morphogenesis							rph	2016-11-09T12:19:37Z					biological_process											owl:Class	
GO:1900867	biolink:NamedThing	sarcinapterin metabolic process	The chemical reactions and pathways involving sarcinapterin.	tmpzr1t_l9r_go_relaxed.owl	sarcinapterin metabolism							tt	2012-06-12T04:34:10Z					biological_process											owl:Class	
GO:0072350	biolink:NamedThing	tricarboxylic acid metabolic process	The chemical reactions and pathways involving dicarboxylic acids, any organic acid containing three carboxyl (COOH) groups or anions (COO-).	tmpzr1t_l9r_go_relaxed.owl	tricarboxylic acid metabolism							mah	2010-11-11T05:07:30Z					biological_process											owl:Class	
GO:0005513	biolink:NamedThing	detection of calcium ion	The series of events in which a calcium ion stimulus is received by a cell and converted into a molecular signal.	tmpzr1t_l9r_go_relaxed.owl	calcium ion detection|detection of Ca2+ ion|calcium ion sensing|Ca2+ ion detection													biological_process											owl:Class	
GO:0009593	biolink:NamedThing	detection of chemical stimulus	The series of events in which a chemical stimulus is received by a cell and converted into a molecular signal.	tmpzr1t_l9r_go_relaxed.owl	perception of chemical stimulus|chemoperception|chemoreception|detection of chemical substance|perception of chemical substance													biological_process											owl:Class	
GO:0034075	biolink:NamedThing	arabidiol synthase activity	Catalysis of the reaction: oxidosqualene + H2O = arabidiol ((13R,14R,17E)-malabarica-17,21-diene-3beta,14-diol).	tmpzr1t_l9r_go_relaxed.owl					RHEA:31035|EC:4.2.1.124|MetaCyc:RXN-9684									molecular_function											owl:Class	
GO:0031559	biolink:NamedThing	oxidosqualene cyclase activity	Catalysis of the cyclization of (S)-2,3-epoxysqualene to form a triterpene.	tmpzr1t_l9r_go_relaxed.owl	2,3-oxidosqualene cyclase activity					Note that the phrase 'oxidosqualene cyclase' has been used to refer to enzymes that catalyze the reaction represented by 'lanosterol synthase activity ; GO:0000250'.								molecular_function											owl:Class	
GO:0140669	biolink:NamedThing	negative regulation of oxytocin production	Any process that stops, prevents, or reduces the rate of production of oxytocin.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/21535						pg	2021-06-24T11:31:45Z					biological_process											owl:Class	
GO:0035052	biolink:NamedThing	dorsal vessel aortic cell fate commitment	The commitment of dorsal vessel cardioblast cells to an aortic cell fate and their capacity to differentiate into aortic cells. An example of this process is found in Drosophila melanogaster.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0045821	biolink:NamedThing	positive regulation of glycolytic process	Any process that activates or increases the frequency, rate or extent of glycolysis.	tmpzr1t_l9r_go_relaxed.owl	activation of glycolysis|up regulation of glycolysis|stimulation of glycolysis|upregulation of glycolysis|up-regulation of glycolysis													biological_process											owl:Class	
GO:0042327	biolink:NamedThing	positive regulation of phosphorylation	Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to a molecule.	tmpzr1t_l9r_go_relaxed.owl	stimulation of phosphorylation|up regulation of phosphorylation|up-regulation of phosphorylation|upregulation of phosphorylation|activation of phosphorylation													biological_process											owl:Class	
GO:1900384	biolink:NamedThing	regulation of flavonol biosynthetic process	Any process that modulates the frequency, rate or extent of flavonol biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl								tb	2012-04-17T10:22:49Z					biological_process											owl:Class	
GO:1902210	biolink:NamedThing	positive regulation of bacterial-type flagellum assembly	Any process that activates or increases the frequency, rate or extent of bacterial-type flagellum assembly.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of bacterial flagellum assembly|up regulation of bacterial-type flagellum assembly|up-regulation of bacterial-type flagellum assembly|upregulation of bacterial-type flagellum assembly|activation of bacterial-type flagellum assembly|activation of bacterial flagellum assembly|up regulation of bacterial flagellum assembly|upregulation of bacterial flagellum assembly|positive regulation of bacterial flagellum assembly							jl	2013-06-11T14:20:30Z					biological_process											owl:Class	
GO:0031346	biolink:NamedThing	positive regulation of cell projection organization	Any process that activates or increases the frequency, rate or extent of the process involved in the formation, arrangement of constituent parts, or disassembly of cell projections.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of cell projection organization|stimulation of cell projection organization|activation of cell projection organization|positive regulation of cell projection organisation|up regulation of cell projection organization|upregulation of cell projection organization|positive regulation of cell projection organization and biogenesis													biological_process											owl:Class	
GO:1903209	biolink:NamedThing	positive regulation of oxidative stress-induced cell death	Any process that activates or increases the frequency, rate or extent of oxidative stress-induced cell death.	tmpzr1t_l9r_go_relaxed.owl	up regulation of cell death in response to oxidative stress|up-regulation of cell death in response to oxidative stress|enhancement of oxidative stress-induced cell death|positive regulation of cell death in response to oxidative stress|activation of cell death in response to oxidative stress|upregulation of cell death in response to oxidative stress							bf	2014-07-22T09:32:19Z					biological_process											owl:Class	
GO:0042149	biolink:NamedThing	cellular response to glucose starvation	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of glucose.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0009267	biolink:NamedThing	cellular response to starvation	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of nourishment.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1900110	biolink:NamedThing	negative regulation of histone H3-K9 dimethylation	Any process that stops, prevents or reduces the frequency, rate or extent of histone H3-K9 dimethylation.	tmpzr1t_l9r_go_relaxed.owl	down regulation of histone lysine H3 K9 dimethylation|inhibition of histone H3 K9 dimethylation|negative regulation of histone lysine H3 K9 dimethylation|down-regulation of histone H3-K9 dimethylation|downregulation of histone lysine H3 K9 dimethylation|inhibition of histone H3-K9 dimethylation|downregulation of histone H3-K9 dimethylation|negative regulation of histone H3 K9 dimethylation|down-regulation of histone H3 K9 dimethylation|downregulation of histone H3 K9 dimethylation|down-regulation of histone lysine H3 K9 dimethylation|down regulation of histone H3 K9 dimethylation|inhibition of histone lysine H3 K9 dimethylation|down regulation of histone H3-K9 dimethylation							bf	2012-02-21T09:06:22Z					biological_process											owl:Class	
GO:1900109	biolink:NamedThing	regulation of histone H3-K9 dimethylation	Any process that modulates the frequency, rate or extent of histone H3-K9 dimethylation.	tmpzr1t_l9r_go_relaxed.owl	regulation of histone H3 K9 dimethylation|regulation of histone lysine H3 K9 dimethylation							bf	2012-02-21T09:06:18Z					biological_process											owl:Class	
GO:0044747	biolink:NamedThing	mature miRNA 3'-end processing	Any process involved in forming distinct miRNA isoforms from a mature miRNA that differ at their 3'-ends.	tmpzr1t_l9r_go_relaxed.owl	miRNA trimming|miRNA 3'-end processing|miRNA 3' end terminal trimming							jl	2012-11-15T13:45:21Z					biological_process											owl:Class	
GO:1904811	biolink:NamedThing	positive regulation of dense core granule transport	Any process that activates or increases the frequency, rate or extent of dense core granule transport.	tmpzr1t_l9r_go_relaxed.owl	upregulation of dense core granule transport|activation of dense core vesicle transport|positive regulation of dense core vesicle transport|up regulation of dense core vesicle transport|up regulation of dense core granule transport|upregulation of dense core vesicle transport|up-regulation of dense core granule transport|up-regulation of dense core vesicle transport|activation of dense core granule transport					cdk-5 in C.elegans (G5ECH7) in PMID:22699897 (inferred from mutant phenotype).		es	2015-11-11T10:40:25Z					biological_process											owl:Class	
GO:0044533	biolink:NamedThing	positive regulation of apoptotic process in other organism	Any process in which an organism activates, maintains or increases the frequency, rate or extent of programmed cell death by apoptosis in a second organism.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-03-21T11:25:24Z					biological_process											owl:Class	
GO:0044532	biolink:NamedThing	modulation of apoptotic process in other organism	A process in which an organism modulates the frequency, rate or extent of apoptosis in a second organism.	tmpzr1t_l9r_go_relaxed.owl	regulation of apoptotic process in other organism							jl	2012-03-21T11:17:18Z					biological_process											owl:Class	
GO:0005883	biolink:NamedThing	neurofilament	A type of intermediate filament found in the core of neuronal axons. Neurofilaments are heteropolymers composed of three type IV polypeptides: NF-L, NF-M, and NF-H (for low, middle, and high molecular weight). Neurofilaments are responsible for the radial growth of an axon and determine axonal diameter.	tmpzr1t_l9r_go_relaxed.owl	type IV intermediate filament				Wikipedia:Neurofilament|NIF_Subcellular:sao1316272517									cellular_component											owl:Class	
GO:0005882	biolink:NamedThing	intermediate filament	A cytoskeletal structure that forms a distinct elongated structure, characteristically 10 nm in diameter, that occurs in the cytoplasm of eukaryotic cells. Intermediate filaments form a fibrous system, composed of chemically heterogeneous subunits and involved in mechanically integrating the various components of the cytoplasmic space. Intermediate filaments may be divided into five chemically distinct classes: Type I, acidic keratins; Type II, basic keratins; Type III, including desmin, vimentin and others; Type IV, neurofilaments and related filaments; and Type V, lamins.	tmpzr1t_l9r_go_relaxed.owl	type I intermediate filament associated protein|type II intermediate filament associated protein|intermediate filament associated protein				FMA:63851|NIF_Subcellular:sao952483289|Wikipedia:Intermediate_filament									cellular_component											owl:Class	
GO:0006364	biolink:NamedThing	rRNA processing	Any process involved in the conversion of a primary ribosomal RNA (rRNA) transcript into one or more mature rRNA molecules.	tmpzr1t_l9r_go_relaxed.owl	35S primary transcript processing											GO:0006365		biological_process											owl:Class	
GO:0034470	biolink:NamedThing	ncRNA processing	Any process that results in the conversion of one or more primary non-coding RNA (ncRNA) transcripts into one or more mature ncRNA molecules.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0009737	biolink:NamedThing	response to abscisic acid	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abscisic acid stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to abscisic acid stimulus													biological_process											owl:Class	
GO:0033993	biolink:NamedThing	response to lipid	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipid stimulus.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:2000091	biolink:NamedThing	negative regulation of mesonephric glomerular mesangial cell proliferation	Any process that stops, prevents, or reduces the frequency, rate or extent of mesonephric glomerular mesangial cell proliferation.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-09-03T06:10:31Z					biological_process											owl:Class	
GO:0030920	biolink:NamedThing	peptidyl-serine acetylation	The acetylation of peptidyl-serine.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0006473	biolink:NamedThing	protein acetylation	The addition of an acetyl group to a protein amino acid. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid.	tmpzr1t_l9r_go_relaxed.owl	protein amino acid acetylation													biological_process											owl:Class	
GO:2000078	biolink:NamedThing	positive regulation of type B pancreatic cell development	Any process that activates or increases the frequency, rate or extent of pancreatic B cell development.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of pancreatic B cell development|positive regulation of pancreatic beta cell development							tb	2010-08-27T11:21:19Z					biological_process											owl:Class	
GO:0070341	biolink:NamedThing	fat cell proliferation	The multiplication or reproduction of fat cells by cell division, resulting in the expansion of their population. A fat cell is an animal connective tissue cell specialized for the synthesis and storage of fat.	tmpzr1t_l9r_go_relaxed.owl	adipocyte proliferation|adipose cell proliferation													biological_process											owl:Class	
GO:2000370	biolink:NamedThing	positive regulation of clathrin-dependent endocytosis	Any process that activates or increases the frequency, rate or extent of clathrin-mediated endocytosis.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of clathrin-mediated endocytosis|positive regulation of clathrin coated pit-dependent endocytosis							mah	2011-02-09T12:36:28Z					biological_process											owl:Class	
GO:0070257	biolink:NamedThing	positive regulation of mucus secretion	Any process that activates or increases the frequency, rate or extent of the regulated release of mucus from a cell or a tissue.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of mucus production													biological_process											owl:Class	
GO:0070255	biolink:NamedThing	regulation of mucus secretion	Any process that modulates the frequency, rate or extent of the regulated release of mucus from a cell or a tissue.	tmpzr1t_l9r_go_relaxed.owl	regulation of mucus production													biological_process											owl:Class	
GO:0106151	biolink:NamedThing	CNBH domain intrinsic ligand binding	Interacting selectivity and noncovalently with a cyclic nucleotide mimicking protein motif that is part of the same protein. The CNBHD is a domain on KCNH channels that creates a binding pocket on the KCNH channel that resembles the cyclic nucleotide- binding domain on other ion channels. It binds to a peptide motif that is part of the same protein rather than a cyclic nucleotide.	tmpzr1t_l9r_go_relaxed.owl						It is unclear if the motif bound by CNBHD is a specific motif or just a beta sheet with the appropriate amino acids.		hjd	2018-09-18T20:47:35Z					molecular_function											owl:Class	
GO:0006269	biolink:NamedThing	DNA replication, synthesis of RNA primer	The synthesis of a short RNA polymer, usually 4-15 nucleotides long, using one strand of unwound DNA as a template; the RNA then serves as a primer from which DNA polymerases extend synthesis.	tmpzr1t_l9r_go_relaxed.owl	replication priming													biological_process											owl:Class	
GO:0032774	biolink:NamedThing	RNA biosynthetic process	The chemical reactions and pathways resulting in the formation of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage. Includes polymerization of ribonucleotide monomers. Refers not only to transcription but also to e.g. viral RNA replication.	tmpzr1t_l9r_go_relaxed.owl	RNA synthesis|RNA biosynthesis|RNA anabolism|RNA formation					Note that, in some cases, viral RNA replication and viral transcription from RNA actually refer to the same process, but may be called differently depending on the focus of a specific research study.								biological_process											owl:Class	
GO:1901176	biolink:NamedThing	lycopene catabolic process	The chemical reactions and pathways resulting in the breakdown of lycopene.	tmpzr1t_l9r_go_relaxed.owl	lycopene degradation|lycopene catabolism|lycopene breakdown							yaf	2012-07-19T09:48:41Z					biological_process											owl:Class	
GO:0016121	biolink:NamedThing	carotene catabolic process	The chemical reactions and pathways resulting in the breakdown of carotenes, hydrocarbon carotenoids.	tmpzr1t_l9r_go_relaxed.owl	carotene breakdown|carotene catabolism|carotene degradation													biological_process											owl:Class	
GO:1904154	biolink:NamedThing	positive regulation of retrograde protein transport, ER to cytosol	Any process that activates or increases the frequency, rate or extent of retrograde protein transport, ER to cytosol.	tmpzr1t_l9r_go_relaxed.owl	upregulation of protein dislocation from ER|activation of retrograde protein transport, endoplasmic reticulum to cytosol|up regulation of protein dislocation from ER|positive regulation of retrograde protein transport, endoplasmic reticulum to cytosol|up-regulation of retrograde protein transport, ER to cytosol|up-regulation of retrograde protein transport, endoplasmic reticulum to cytosol|upregulation of retrograde protein transport, ER to cytosol|up-regulation of protein dislocation from ER|positive regulation of protein retrotranslocation from ER|up regulation of retrograde protein transport, endoplasmic reticulum to cytosol|up regulation of retrograde protein transport, ER to cytosol|activation of retrograde protein transport, ER to cytosol|upregulation of retrograde protein transport, endoplasmic reticulum to cytosol|activation of protein dislocation from ER|up-regulation of protein retrotranslocation from ER|positive regulation of protein dislocation from ER							bf	2015-04-15T09:23:19Z					biological_process											owl:Class	
GO:0070863	biolink:NamedThing	positive regulation of protein exit from endoplasmic reticulum	Any process that activates or increases the frequency, rate or extent of directed movement of proteins from the endoplasmic reticulum.	tmpzr1t_l9r_go_relaxed.owl	stimulation of protein exit from endoplasmic reticulum|positive regulation of protein export from endoplasmic reticulum|upregulation of protein exit from endoplasmic reticulum|up-regulation of protein exit from endoplasmic reticulum|positive regulation of protein export from ER|up regulation of protein exit from endoplasmic reticulum|positive regulation of protein exit from ER|activation of protein exit from endoplasmic reticulum							mah	2009-08-17T03:50:04Z					biological_process											owl:Class	
GO:1904415	biolink:NamedThing	regulation of xenophagy	Any process that modulates the frequency, rate or extent of xenophagy.	tmpzr1t_l9r_go_relaxed.owl						An example of this is mouse Tbk1 (UniProt symbol, Q9WUN2) in PMID:21617041 (inferred from mutant phenotype).		pad	2015-06-29T12:30:47Z					biological_process											owl:Class	
GO:0006210	biolink:NamedThing	thymine catabolic process	The chemical reactions and pathways resulting in the breakdown of thymine, 5-methyluracil, one of the two major pyrimidine bases present (as thymidine) in DNA but not found in RNA other than (as ribothymidine) in transfer RNA, where it is a minor base.	tmpzr1t_l9r_go_relaxed.owl	thymine catabolism|thymine breakdown|thymine degradation													biological_process											owl:Class	
GO:0019859	biolink:NamedThing	thymine metabolic process	The chemical reactions and pathways involving thymine, 5-methyluracil, one of the two major pyrimidine bases present (as thymidine) in DNA but not found in RNA other than (as ribothymidine) in transfer RNA, where it is a minor base.	tmpzr1t_l9r_go_relaxed.owl	thymine metabolism													biological_process											owl:Class	
GO:0002754	biolink:NamedThing	intracellular endosomal pattern recognition receptor signaling pathway	Any series of molecular signals generated as a consequence of an intracellular vesicle pattern recognition receptor (PRR) binding to one of its physiological ligands. PRRs bind pathogen-associated molecular pattern (PAMPs), structures conserved among microbial species.	tmpzr1t_l9r_go_relaxed.owl	intracellular vesicle pathogen receptor signaling pathway|intracellular vesicle pattern recognition receptor signalling pathway|intracellular vesicle pattern recognition receptor signaling pathway|intracellular vesicle PRR signaling pathway|intracellular vesicle PAMP receptor signaling pathway	https://github.com/geneontology/go-ontology/issues/18679												biological_process											owl:Class	
GO:0002221	biolink:NamedThing	pattern recognition receptor signaling pathway	Any series of molecular signals generated as a consequence of a pattern recognition receptor (PRR) binding to one of its physiological ligands. PRRs bind pathogen-associated molecular pattern (PAMPs), structures conserved among microbial species, or damage-associated molecular pattern (DAMPs), endogenous molecules released from damaged cells.	tmpzr1t_l9r_go_relaxed.owl	PAMP receptor signaling pathway|PRR signaling pathway|pathogen receptor signaling pathway|pathogen receptor signalling pathway	https://github.com/geneontology/go-ontology/issues/18588												biological_process											owl:Class	
GO:0034055	biolink:NamedThing	effector-mediated induction of programmed cell death in host	A symbiont process in which a molecule secreted by the symbiont activates a programmed cell death pathway in the host to suppress the host innate immune response. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	up-regulation by symbiont of host defense-related programmed cell death|upregulation by symbiont of host defense-related programmed cell death|enhancement by symbiont of host defense-related programmed cell death|up regulation by symbiont of host defense-related programmed cell death|stimulation by symbiont of host defense-related programmed cell death|positive regulation by symbiont of host defense-related PCD|positive regulation by symbiont of host defense-related programmed cell death|activation by symbiont of host defense-related programmed cell death	https://github.com/geneontology/go-ontology/issues/20284				Note that this term is used to annotate gene products of the symbiont.								biological_process											owl:Class	
GO:0140418	biolink:NamedThing	effector-mediated modulation of host process by symbiont	A process mediated by a molecule secreted by a symbiont that results in the modulation (either activation or suppresion) of a host structure or process. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	effector mediated modulation of host process by symbiont|effector triggered modulation of host process by symbiont|effector-dependent modulation of host process by symbiont	https://github.com/geneontology/go-ontology/issues/18605|https://github.com/geneontology/go-ontology/issues/20971						pg	2020-01-29T21:24:42Z					biological_process											owl:Class	
GO:0010396	biolink:NamedThing	rhamnogalacturonan II metabolic process	The chemical reactions and pathways involving rhamnogalacturonan II, a low molecular mass (5-10KDa) pectic polysaccharide. The backbone of RG-II contains at least 8 1,4-linked alpha-D-GalpA residues.	tmpzr1t_l9r_go_relaxed.owl	rhamnogalacturonan II metabolism													biological_process											owl:Class	
GO:0010393	biolink:NamedThing	galacturonan metabolic process	The chemical reactions and pathways involving galacturonan, a pectin polymer containing a backbone of alpha-(1->4)-linked D-galacturonic acid residues.	tmpzr1t_l9r_go_relaxed.owl	galacturonan metabolism													biological_process											owl:Class	
GO:0044505	biolink:NamedThing	positive regulation of G protein-coupled receptor activity in other organism	A process that activates or increases the frequency, rate or extent of the activity of a G protein-coupled receptor in a second organism.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of G-protein coupled receptor activity in other organism|regulation of G-protein coupled receptor activity in other organism							jl	2012-02-23T04:24:17Z					biological_process											owl:Class	
GO:2000273	biolink:NamedThing	positive regulation of signaling receptor activity	Any process that activates or increases the frequency, rate or extent of signaling receptor activity.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of signalling receptor activity							bf	2010-12-02T09:28:50Z					biological_process											owl:Class	
GO:0051628	biolink:NamedThing	positive regulation of epinephrine uptake	Any process that activates or increases the frequency, rate or extent of the directed movement of epinephrine into a cell.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of adrenaline uptake|activation of epinephrine uptake|up-regulation of epinephrine uptake|up regulation of epinephrine uptake|positive regulation of epinephrine import|stimulation of epinephrine uptake|upregulation of epinephrine uptake													biological_process											owl:Class	
GO:0051626	biolink:NamedThing	regulation of epinephrine uptake	Any process that modulates the frequency, rate or extent of the directed movement of the neurotransmitter epinephrine into a cell.	tmpzr1t_l9r_go_relaxed.owl	regulation of epinephrine import|regulation of adrenaline uptake													biological_process											owl:Class	
GO:0006303	biolink:NamedThing	double-strand break repair via nonhomologous end joining	The repair of a double-strand break in DNA in which the two broken ends are rejoined with little or no sequence complementarity. Information at the DNA ends may be lost due to the modification of broken DNA ends. This term covers instances of separate pathways, called classical (or canonical) and alternative nonhomologous end joining (C-NHEJ and A-NHEJ). These in turn may further branch into sub-pathways, but evidence is still unclear.	tmpzr1t_l9r_go_relaxed.owl	NHEJ													biological_process											owl:Class	
GO:0006302	biolink:NamedThing	double-strand break repair	The repair of double-strand breaks in DNA via homologous and nonhomologous mechanisms to reform a continuous DNA helix.	tmpzr1t_l9r_go_relaxed.owl						Note that the processes of nuclear double-strand break repair and mitochondrial double-strand break repair are genetically separable (PMID:22214610). To annotate gene products involved in mitochondrial double-strand break repair, please use GO:0097551 'mitochondrial double-strand break repair'.								biological_process											owl:Class	
GO:1901110	biolink:NamedThing	actinorhodin metabolic process	The chemical reactions and pathways involving actinorhodin.	tmpzr1t_l9r_go_relaxed.owl	actinorhodin metabolism							yaf	2012-07-11T03:05:37Z					biological_process											owl:Class	
GO:1903027	biolink:NamedThing	regulation of opsonization	Any process that modulates the frequency, rate or extent of opsonization.	tmpzr1t_l9r_go_relaxed.owl								rl	2014-05-16T17:34:41Z					biological_process											owl:Class	
GO:1901889	biolink:NamedThing	negative regulation of cell junction assembly	Any process that stops, prevents or reduces the frequency, rate or extent of cell junction assembly.	tmpzr1t_l9r_go_relaxed.owl	inhibition of cell junction assembly|down regulation of cell junction assembly|down-regulation of cell junction assembly|downregulation of cell junction assembly							tb	2013-02-06T19:40:41Z					biological_process											owl:Class	
GO:1901888	biolink:NamedThing	regulation of cell junction assembly	Any process that modulates the frequency, rate or extent of cell junction assembly.	tmpzr1t_l9r_go_relaxed.owl								tb	2013-02-06T19:40:32Z					biological_process											owl:Class	
GO:0015958	biolink:NamedThing	bis(5'-nucleosidyl) oligophosphate catabolic process	The chemical reactions and pathways resulting in the breakdown of a bis(5'-nucleosidyl) oligophosphate, a compound formed of two nucleosides joined together through their 5' carbons by a chain of phosphate molecules.	tmpzr1t_l9r_go_relaxed.owl	bis(5'-nucleosidyl) oligophosphate catabolism|bis(5'-nucleosidyl) oligophosphate breakdown|bis(5'-nucleosidyl) oligophosphate degradation													biological_process											owl:Class	
GO:0009166	biolink:NamedThing	nucleotide catabolic process	The chemical reactions and pathways resulting in the breakdown of nucleotides, any nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the glycose moiety; may be mono-, di- or triphosphate; this definition includes cyclic-nucleotides (nucleoside cyclic phosphates).	tmpzr1t_l9r_go_relaxed.owl	nucleotide catabolism|nucleotide degradation|nucleotide breakdown													biological_process											owl:Class	
GO:0042204	biolink:NamedThing	s-triazine compound catabolic process	The chemical reactions and pathways resulting in the breakdown of any s-triazine compound. These compounds include many pesticides of widespread use in agriculture, and are characterized by a symmetrical hexameric ring consisting of alternating carbon and nitrogen atoms.	tmpzr1t_l9r_go_relaxed.owl	s-triazine compound degradation|s-triazine compound catabolism|s-triazine compound breakdown				UM-BBD_pathwayID:tria									biological_process											owl:Class	
GO:0042178	biolink:NamedThing	xenobiotic catabolic process	The chemical reactions and pathways resulting in the breakdown of a xenobiotic compound, a compound foreign to the organim exposed to it. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical.	tmpzr1t_l9r_go_relaxed.owl	exogenous drug degradation|exogenous drug catabolism|xenobiotic degradation|exogenous drug catabolic process|xenobiotic breakdown|drug catabolism|xenobiotic catabolism|drug catabolic process|drug breakdown|exogenous drug breakdown|drug degradation	https://github.com/geneontology/go-ontology/issues/19460										GO:0042737|GO:0042738		biological_process											owl:Class	
GO:1905130	biolink:NamedThing	carcinine import across plasma membrane	The directed movement of carcinine from outside of a cell, across the plasma membrane and into the cytosol.	tmpzr1t_l9r_go_relaxed.owl								dph	2016-04-12T15:15:18Z					biological_process											owl:Class	
GO:0045117	biolink:NamedThing	azole transmembrane transport	The directed movement of azoles, heterocyclic compounds found in many biologically important substances, across a lipid bilayer, across a membrane.	tmpzr1t_l9r_go_relaxed.owl	azole transport													biological_process											owl:Class	
GO:2000995	biolink:NamedThing	negative regulation of mannan catabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of mannan catabolic process.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of mannan breakdown|negative regulation of mannan catabolism|negative regulation of mannan degradation							tt	2011-08-08T03:19:11Z					biological_process											owl:Class	
GO:2000994	biolink:NamedThing	regulation of mannan catabolic process	Any process that modulates the frequency, rate or extent of mannan catabolic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of mannan catabolism|regulation of mannan breakdown|regulation of mannan degradation							tt	2011-08-08T03:19:03Z					biological_process											owl:Class	
GO:0034389	biolink:NamedThing	lipid droplet organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lipid particle.	tmpzr1t_l9r_go_relaxed.owl	lipid particle organization|adiposome organization|lipid particle organisation|lipid body organization|lipid particle organization and biogenesis	https://github.com/geneontology/go-ontology/issues/15963|https://github.com/geneontology/go-ontology/issues/13534												biological_process											owl:Class	
GO:0006996	biolink:NamedThing	organelle organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an organelle within a cell. An organelle is an organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.	tmpzr1t_l9r_go_relaxed.owl	organelle organisation|single-organism organelle organization|organelle organization and biogenesis|single organism organelle organization							jl	2013-12-19T15:25:51Z			GO:1902589		biological_process											owl:Class	
GO:0010746	biolink:NamedThing	regulation of long-chain fatty acid import across plasma membrane	Any process that modulates the rate, frequency or extent of plasma membrane long-chain fatty acid transport. Plasma membrane long-chain fatty acid transport is the directed movement of long-chain fatty acids across the plasma membrane. A long-chain fatty acid is a fatty acid with a chain length between C13 and C22.	tmpzr1t_l9r_go_relaxed.owl	regulation of plasma membrane long-chain fatty acid transport													biological_process											owl:Class	
GO:0034762	biolink:NamedThing	regulation of transmembrane transport	Any process that modulates the frequency, rate or extent of the directed movement of a solute from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	regulation of membrane transport													biological_process											owl:Class	
GO:0033864	biolink:NamedThing	positive regulation of NAD(P)H oxidase activity	Any process that activates or increases the activity of the enzyme NAD(P)H oxidase.	tmpzr1t_l9r_go_relaxed.owl	stimulation of NAD(P)H oxidase activity|up-regulation of NAD(P)H oxidase activity|activation of NAD(P)H oxidase activity|up regulation of NAD(P)H oxidase activity|upregulation of NAD(P)H oxidase activity													biological_process											owl:Class	
GO:0005272	biolink:NamedThing	sodium channel activity	Enables the facilitated diffusion of a sodium ion (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-3295580|Reactome:R-HSA-2730664									molecular_function											owl:Class	
GO:0005261	biolink:NamedThing	cation channel activity	Enables the energy-independent passage of cations across a lipid bilayer down a concentration gradient.	tmpzr1t_l9r_go_relaxed.owl	non-selective cation channel activity|cation diffusion facilitator activity				Reactome:R-HSA-426223|Reactome:R-HSA-169683|Reactome:R-HSA-1168376|Reactome:R-HSA-2089943|Reactome:R-HSA-4420052|Reactome:R-HSA-1296043							GO:0015281|GO:0015338		molecular_function											owl:Class	
GO:0060520	biolink:NamedThing	activation of prostate induction by androgen receptor signaling pathway	Any series of molecular signals generated as a consequence of an androgen binding to its receptor in the urogenital sinus mesenchyme that initiates prostate induction. Prostate induction is the close range interaction of the urogenital sinus mesenchyme and the urogenital sinus epithelium that causes the cells of the urogenital sinus epithelium to change their fates and specify the development of the prostate gland.	tmpzr1t_l9r_go_relaxed.owl	activation of prostate induction by androgen receptor signalling pathway													biological_process											owl:Class	
GO:0010647	biolink:NamedThing	positive regulation of cell communication	Any process that increases the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0050592	biolink:NamedThing	4-hydroxyphenylacetaldehyde oxime monooxygenase activity	Catalysis of the reaction: (Z)-(4-hydroxyphenyl)acetaldehyde oxime + H(+) + NADPH + O(2) = (S)-4-hydroxymandelonitrile + 2 H(2)O + NADP(+).	tmpzr1t_l9r_go_relaxed.owl	(Z)-4-hydroxyphenylacetaldehyde oxime,NADPH:oxygen oxidoreductase activity|4-hydroxyphenylacetaldehyde oxime,NADPH:oxygen oxidoreductase activity|NADPH-cytochrome P450 reductase (CYP71E1)|cytochrome P450-II-dependent monooxygenase activity|cytochrome P450II-dependent monooxygenase activity|4-hydroxybenzeneacetaldehyde oxime monooxygenase activity|CYP71E1 activity				EC:1.14.14.37|MetaCyc:1.14.13.68-RXN|KEGG_REACTION:R05728|RHEA:18401									molecular_function											owl:Class	
GO:0060557	biolink:NamedThing	positive regulation of vitamin D biosynthetic process	Any process that increases the rate, frequency or extent of a vitamin D biosynthetic process. Vitamin D biosynthesis is the chemical reactions and pathways resulting in the formation of vitamin D, any of a group of related, fat-soluble compounds that are derived from delta-5,7 steroids and play a central role in calcium metabolism. Specific forms of vitamin D include calciferol (ergocalciferol; vitamin D2) and cholecalciferol (calciol; vitamin D3).	tmpzr1t_l9r_go_relaxed.owl								dph	2009-04-13T02:46:14Z					biological_process											owl:Class	
GO:0030436	biolink:NamedThing	asexual sporulation	The formation of spores derived from the products of an asexual cell division. Examples of this process are found in bacteria and fungi.	tmpzr1t_l9r_go_relaxed.owl	mitotic sporulation|asexual reproductive sporulation|mitotic spore formation|asexual spore formation													biological_process											owl:Class	
GO:0019954	biolink:NamedThing	asexual reproduction	The biological process in which new individuals are produced by either a single cell or a group of cells, in the absence of any sexual process.	tmpzr1t_l9r_go_relaxed.owl	parthenogenesis				Wikipedia:Asexual_reproduction									biological_process											owl:Class	
GO:0099008	biolink:NamedThing	viral entry via permeabilization of inner membrane	The entry of a non-enveloped virus into the cytoplasm of a host prokaryotic cell, following fusion with the outer membrane, via permeabilization of the plasma (inner) membrane.  In the case of some double stranded RNA viruses of prokaryotes this occurs via interaction of a membrane-interacting component of the capsid, leading to depolarization an permeabilization of the plasma membrane.	tmpzr1t_l9r_go_relaxed.owl	viral penetration via permeabilization of host membrane				VZ:985									biological_process											owl:Class	
GO:0140267	biolink:NamedThing	viral entry via permeabilization of host membrane	The entry of a virus into the cytoplasm of a host cell, triggered by an interaction between the bilayer of a host membrane and a membrane-penetration capsid protein. Results in release of the virus contents into the host cell cytoplasm.	tmpzr1t_l9r_go_relaxed.owl								pg	2018-09-25T14:33:03Z					biological_process											owl:Class	
GO:1902078	biolink:NamedThing	positive regulation of lateral motor column neuron migration	Any process that activates or increases the frequency, rate or extent of lateral motor column neuron migration.	tmpzr1t_l9r_go_relaxed.owl	activation of lateral motor column neuron migration|up-regulation of lateral motor column neuron migration|upregulation of lateral motor column neuron migration|up regulation of lateral motor column neuron migration							pr	2013-04-23T14:42:28Z					biological_process											owl:Class	
GO:1902076	biolink:NamedThing	regulation of lateral motor column neuron migration	Any process that modulates the frequency, rate or extent of lateral motor column neuron migration.	tmpzr1t_l9r_go_relaxed.owl								pr	2013-04-23T14:42:18Z					biological_process											owl:Class	
GO:0033262	biolink:NamedThing	regulation of nuclear cell cycle DNA replication	Any process that modulates the frequency, rate or extent of The DNA-dependent DNA replication that occurs in the nucleus of eukaryotic organisms as part of the cell cycle.	tmpzr1t_l9r_go_relaxed.owl	regulation of DNA replication involved in S-phase|regulation of DNA replication during S phase|regulation of DNA replication involved in S phase													biological_process											owl:Class	
GO:0035189	biolink:NamedThing	Rb-E2F complex	A multiprotein complex containing a heterodimeric E2F transcription factor and a Retinoblastoma (Rb) family member. This complex is capable of repressing transcription of E2F-regulated genes in order to regulate cell cycle progression.	tmpzr1t_l9r_go_relaxed.owl	retinoblastoma-E2F complex													cellular_component											owl:Class	
GO:0015885	biolink:NamedThing	5-formyltetrahydrofolate transport	The directed movement of 5-formyltetrahydrofolate, the formylated derivative of tetrahydrofolate, into, out of, within, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0006835	biolink:NamedThing	dicarboxylic acid transport	The directed movement of dicarboxylic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	sodium:dicarboxylate transport											GO:0006841		biological_process											owl:Class	
GO:0071656	biolink:NamedThing	negative regulation of granulocyte colony-stimulating factor production	Any process that stops, prevents, or reduces the frequency, rate, or extent of production of granulocyte colony stimulating factor.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of colony stimulating factor 3 (granulocyte) production|negative regulation of CSF3 production|negative regulation of filgrastim production|negative regulation of pluripoietin production|negative regulation of G-CSF production|negative regulation of granulocyte colony stimulating factor production|negative regulation of lenograstim production							mah	2010-02-12T10:41:14Z					biological_process											owl:Class	
GO:1901257	biolink:NamedThing	negative regulation of macrophage colony-stimulating factor production	Any process that stops, prevents or reduces the frequency, rate or extent of macrophage colony-stimulating factor production.	tmpzr1t_l9r_go_relaxed.owl	down regulation of M-CSF production|downregulation of M-CSF production|downregulation of macrophage colony-stimulating factor production|inhibition of macrophage colony-stimulating factor production|down-regulation of macrophage colony-stimulating factor production|down-regulation of M-CSF production|down regulation of macrophage colony-stimulating factor production|inhibition of M-CSF production|negative regulation of M-CSF production							vk	2012-08-10T08:28:28Z					biological_process											owl:Class	
GO:1900714	biolink:NamedThing	negative regulation of violaceol I biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of violaceol I biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	down regulation of violaceol I formation|down-regulation of violaceol I biosynthetic process|downregulation of violaceol I biosynthesis|down-regulation of violaceol I biosynthesis|downregulation of violaceol I biosynthetic process|inhibition of violaceol I anabolism|inhibition of violaceol I biosynthesis|downregulation of violaceol I formation|down-regulation of violaceol I anabolism|down regulation of violaceol I anabolism|downregulation of violaceol I anabolism|negative regulation of violaceol I anabolism|down regulation of violaceol I biosynthesis|negative regulation of violaceol I biosynthesis|down regulation of violaceol I biosynthetic process|negative regulation of violaceol I synthesis|down-regulation of violaceol I synthesis|inhibition of violaceol I biosynthetic process|inhibition of violaceol I formation|inhibition of violaceol I synthesis|negative regulation of violaceol I formation|down regulation of violaceol I synthesis|downregulation of violaceol I synthesis|down-regulation of violaceol I formation							di	2012-05-22T05:04:33Z					biological_process											owl:Class	
GO:0048138	biolink:NamedThing	germ-line cyst encapsulation	Formation of a single follicular epithelium around the germ-line derived cells of a cyst.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0003006	biolink:NamedThing	developmental process involved in reproduction	A developmental process in which a progressive change in the state of some part of an organism, germline or somatic, specifically contributes to its ability to form offspring.	tmpzr1t_l9r_go_relaxed.owl	puberty|reproductive developmental process													biological_process											owl:Class	
GO:0071263	biolink:NamedThing	negative regulation of translational initiation in response to starvation	Any process that stops, prevents or reduces the rate of translation initiation, as a result of deprivation of nourishment.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of translational initiation in response to nutrient starvation|downregulation of translation initiation in response to starvation|down regulation of translation initiation in response to starvation|down-regulation of translation initiation in response to starvation|inhibition of translation initiation in response to starvation							mah	2009-12-08T05:33:12Z					biological_process											owl:Class	
GO:0032057	biolink:NamedThing	negative regulation of translational initiation in response to stress	Any process that stops, prevents or reduces the rate of translation initiation as a result of a stimulus indicating the organism is under stress.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of translation initiation in response to stress|downregulation of translation initiation in response to stress|inhibition of translation initiation in response to stress|down regulation of translation initiation in response to stress													biological_process											owl:Class	
GO:1901255	biolink:NamedThing	nucleotide-excision repair involved in interstrand cross-link repair	Any nucleotide-excision repair that is involved in interstrand cross-link repair.	tmpzr1t_l9r_go_relaxed.owl	NER involved in ICL repair|nucleotide-excision repair involved in ICL repair|NER involved in interstrand cross-link repair							vw	2012-08-09T06:09:50Z					biological_process											owl:Class	
GO:0006289	biolink:NamedThing	nucleotide-excision repair	A DNA repair process in which a small region of the strand surrounding the damage is removed from the DNA helix as an oligonucleotide. The small gap left in the DNA helix is filled in by the sequential action of DNA polymerase and DNA ligase. Nucleotide excision repair recognizes a wide range of substrates, including damage caused by UV irradiation (pyrimidine dimers and 6-4 photoproducts) and chemicals (intrastrand cross-links and bulky adducts).	tmpzr1t_l9r_go_relaxed.owl	pyrimidine-dimer repair, DNA damage excision|intrastrand cross-link repair|NER					Note that although intrastrand cross-link repair is not exactly synonymous with nucleotide excision repair, nucleotide excision repair includes the repair of intrastrand cross-links. The synonym field is being used to reflect the broad substrate specificity of nucleotide excision repair.						GO:0045001		biological_process											owl:Class	
GO:0032707	biolink:NamedThing	negative regulation of interleukin-23 production	Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-23 production.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of interleukin-23 biosynthetic process|inhibition of interleukin-23 production|downregulation of interleukin-23 production|down-regulation of interleukin-23 production|negative regulation of IL-23 production|down regulation of interleukin-23 production											GO:0045397		biological_process											owl:Class	
GO:0032667	biolink:NamedThing	regulation of interleukin-23 production	Any process that modulates the frequency, rate, or extent of interleukin-23 production.	tmpzr1t_l9r_go_relaxed.owl	regulation of IL-23 production|regulation of interleukin-23 synthesis|regulation of interleukin-23 biosynthesis|regulation of IL-23 biosynthetic process|regulation of interleukin-23 biosynthetic process|regulation of interleukin-23 anabolism|regulation of interleukin-23 formation											GO:0045396		biological_process											owl:Class	
GO:1901264	biolink:NamedThing	carbohydrate derivative transport	The directed movement of a carbohydrate derivative into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl								bf	2012-08-16T14:51:22Z					biological_process											owl:Class	
GO:0090042	biolink:NamedThing	tubulin deacetylation	The removal of an acetyl group from tubulin. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-08-03T11:50:47Z					biological_process											owl:Class	
GO:0006476	biolink:NamedThing	protein deacetylation	The removal of an acetyl group from a protein amino acid. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid.	tmpzr1t_l9r_go_relaxed.owl	protein amino acid deacetylation													biological_process											owl:Class	
GO:1900258	biolink:NamedThing	positive regulation of beta1-adrenergic receptor activity	Any process that activates or increases the frequency, rate or extent of beta1-adrenergic receptor activity.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of beta1-adrenergic receptor activity|positive regulation of beta1 adrenoceptor|up regulation of beta1-adrenergic receptor activity|upregulation of beta1-adrenergic receptor activity|up regulation of beta1 adrenoceptor|activation of beta1 adrenoceptor|up-regulation of beta1 adrenoceptor|activation of beta1-adrenergic receptor activity|upregulation of beta1 adrenoceptor							tb	2012-04-03T10:59:49Z					biological_process											owl:Class	
GO:0150127	biolink:NamedThing	regulation of interleukin-33 production	Any process that modulates the frequency, rate or extent of interleukin-33 production.	tmpzr1t_l9r_go_relaxed.owl	regulation of interleukin-33 secretion|regulation of interleukin-33 biosynthetic process							bc	2019-12-03T05:54:03Z			GO:0150130|GO:0150123		biological_process											owl:Class	
GO:0010629	biolink:NamedThing	negative regulation of gene expression	Any process that decreases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.	tmpzr1t_l9r_go_relaxed.owl	gene silencing					This term covers any process that negatively regulates the rate of production of a mature gene product, and so includes processes that negatively regulate that rate by reducing the level, stability or availability of intermediates in the process of gene expression. For example, it covers any process that reduces the level, stability or availability of mRNA or circRNA for translation and thereby reduces the rate of production of the encoded protein via translation.								biological_process											owl:Class	
GO:0071480	biolink:NamedThing	cellular response to gamma radiation	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gamma radiation stimulus. Gamma radiation is a form of electromagnetic radiation (EMR) or light emission of a specific frequency produced from sub-atomic particle interaction, such as electron-positron annihilation and radioactive decay. Gamma rays are generally characterized as EMR having the highest frequency and energy, and also the shortest wavelength, within the electromagnetic radiation spectrum.	tmpzr1t_l9r_go_relaxed.owl	cellular response to gamma ray|cellular response to gamma-ray photon							mah	2009-12-18T02:00:50Z					biological_process											owl:Class	
GO:0010332	biolink:NamedThing	response to gamma radiation	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gamma radiation stimulus. Gamma radiation is a form of electromagnetic radiation (EMR) or light emission of a specific frequency produced from sub-atomic particle interaction, such as electron-positron annihilation and radioactive decay. Gamma rays are generally characterized as EMR having the highest frequency and energy, and also the shortest wavelength, within the electromagnetic radiation spectrum.	tmpzr1t_l9r_go_relaxed.owl	response to gamma ray|response to gamma-ray photon													biological_process											owl:Class	
GO:1900606	biolink:NamedThing	tensidol B metabolic process	The chemical reactions and pathways involving tensidol B.	tmpzr1t_l9r_go_relaxed.owl	tensidol B metabolism							di	2012-05-15T06:58:21Z					biological_process											owl:Class	
GO:0044149	biolink:NamedThing	positive regulation of formation of structure involved in a symbiotic process	Any process that activates or increases the frequency, rate or extent of the progression of an organism from an initial condition to a later condition, occurring in, on or near the exterior of its host organism.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of development of symbiont involved in interaction with host|positive regulation of development of symbiont during interaction with host	https://github.com/geneontology/go-ontology/issues/20305				This term partially replaces the obsolete term 'positive regulation of growth or development of symbiont during interaction with host ; GO:0075339'. See also 'positive regulation of growth of symbiont during interaction with host ; GO:0044148'.		jl	2009-08-06T02:20:55Z					biological_process											owl:Class	
GO:0048518	biolink:NamedThing	positive regulation of biological process	Any process that activates or increases the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.	tmpzr1t_l9r_go_relaxed.owl	upregulation of biological process|positive regulation of physiological process|up regulation of biological process|activation of biological process|up-regulation of biological process|stimulation of biological process											GO:0043119		biological_process											owl:Class	
GO:0052765	biolink:NamedThing	reduced coenzyme F420 oxidase activity	Catalysis of the reaction: 2 reduced coenzyme F420 + O2 = 2 coenzyme F420 + 2 H2O.	tmpzr1t_l9r_go_relaxed.owl	F420H2:oxygen oxidoreductase activity|coenzyme F420H2 oxidase activity|F420H2 oxidase activity							ai	2011-09-29T04:33:54Z					molecular_function											owl:Class	
GO:0033634	biolink:NamedThing	positive regulation of cell-cell adhesion mediated by integrin	Any process that activates or increases the frequency, rate, or extent of cell-cell adhesion mediated by integrin.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of cell-cell adhesion mediated by integrin complex													biological_process											owl:Class	
GO:0022409	biolink:NamedThing	positive regulation of cell-cell adhesion	Any process that activates or increases the rate or extent of cell adhesion to another cell.	tmpzr1t_l9r_go_relaxed.owl	upregulation of cell-cell adhesion|stimulation of cell-cell adhesion|up regulation of cell-cell adhesion|up-regulation of cell-cell adhesion|activation of cell-cell adhesion													biological_process											owl:Class	
GO:0014838	biolink:NamedThing	myoblast fate specification involved in skeletal muscle regeneration	The process in which a satellite cell becomes capable of differentiating autonomously into a myoblast in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed. This occurs as part of skeletal muscle regeneration. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0048626	biolink:NamedThing	myoblast fate specification	The process in which a cell becomes capable of differentiating autonomously into a myoblast in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0150200	biolink:NamedThing	regulation of transport across blood-brain barrier	Any process that modulates the frequency, rate or extent of transport across the blood-brain barrier.	tmpzr1t_l9r_go_relaxed.owl								bc	2020-03-26T19:22:26Z					biological_process											owl:Class	
GO:2001285	biolink:NamedThing	negative regulation of BMP secretion	Any process that stops, prevents or reduces the frequency, rate or extent of BMP secretion.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of BMP protein secretion|negative regulation of bone morphogenetic protein secretion							bf	2011-12-15T02:15:36Z					biological_process											owl:Class	
GO:0023057	biolink:NamedThing	negative regulation of signaling	Any process that stops, prevents, or reduces the frequency, rate or extent of a signaling process.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of signaling process|negative regulation of signalling process								2010-02-16T09:30:50Z					biological_process											owl:Class	
GO:0010903	biolink:NamedThing	negative regulation of very-low-density lipoprotein particle remodeling	Any process that decreases the rate, frequency or extent of very-low-density lipoprotein particle remodeling. Very-low-density lipoprotein particle remodeling is the acquisition, loss or modification of a protein or lipid within a very-low-density lipoprotein particle, including the hydrolysis of triglyceride by hepatic lipase or lipoprotein lipase and the subsequent loss of free fatty acid.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of VLDL remodeling													biological_process											owl:Class	
GO:0010901	biolink:NamedThing	regulation of very-low-density lipoprotein particle remodeling	Any process that modulates the rate, frequency or extent of very-low-density lipoprotein particle remodeling. Very-low-density lipoprotein particle remodeling is the acquisition, loss or modification of a protein or lipid within a very-low-density lipoprotein particle, including the hydrolysis of triglyceride by hepatic lipase or lipoprotein lipase and the subsequent loss of free fatty acid.	tmpzr1t_l9r_go_relaxed.owl	regulation of VLDL remodeling													biological_process											owl:Class	
GO:0061358	biolink:NamedThing	negative regulation of Wnt protein secretion	Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of a Wnt protein from a cell.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-10-08T01:15:15Z					biological_process											owl:Class	
GO:0018905	biolink:NamedThing	dimethyl ether metabolic process	The chemical reactions and pathways involving dimethyl ether, CH3-O-CH3, the simplest ether. Dimethyl ether, also known wood ether and methyl ether, is a colorless gas that has been used in refrigeration applications.	tmpzr1t_l9r_go_relaxed.owl	dimethyl ether metabolism|methyl ether metabolism|methyl ether metabolic process				UM-BBD_pathwayID:dme									biological_process											owl:Class	
GO:0006805	biolink:NamedThing	xenobiotic metabolic process	The chemical reactions and pathways involving a xenobiotic compound, a compound foreign to the organim exposed to it. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical.	tmpzr1t_l9r_go_relaxed.owl	drug metabolic process|drug metabolism|xenobiotic metabolism	https://github.com/geneontology/go-ontology/issues/19460			Wikipedia:Drug_metabolism|Wikipedia:Xenobiotic_metabolism							GO:0017144		biological_process											owl:Class	
GO:0032665	biolink:NamedThing	regulation of interleukin-21 production	Any process that modulates the frequency, rate, or extent of interleukin-21 production.	tmpzr1t_l9r_go_relaxed.owl	regulation of interleukin-21 biosynthetic process|regulation of IL-21 production											GO:0045390		biological_process											owl:Class	
GO:0044610	biolink:NamedThing	FMN transmembrane transporter activity	Enables the directed movement of flavine mononucleotide (FMN) from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	flavine mononucleotide transmembrane transporter activity							jl	2012-05-30T03:09:19Z					molecular_function											owl:Class	
GO:1901505	biolink:NamedThing	carbohydrate derivative transmembrane transporter activity	Enables the transfer of carbohydrate derivative from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	carbohydrate derivative transporter activity							pr	2012-10-17T10:31:22Z					molecular_function											owl:Class	
GO:0060340	biolink:NamedThing	positive regulation of type I interferon-mediated signaling pathway	Any process that increases the rate, frequency or extent of a type I interferon-mediated signaling pathway. A type I interferon-mediated signaling pathway is the series of molecular events generated as a consequence of a type I interferon binding to a cell surface receptor.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of type I interferon-mediated signalling pathway													biological_process											owl:Class	
GO:0045089	biolink:NamedThing	positive regulation of innate immune response	Any process that activates or increases the frequency, rate or extent of the innate immune response, the organism's first line of defense against infection.	tmpzr1t_l9r_go_relaxed.owl	stimulation of innate immune response|upregulation of innate immune response|up-regulation of innate immune response|up regulation of innate immune response													biological_process											owl:Class	
GO:1905920	biolink:NamedThing	positive regulation of CoA-transferase activity	Any process that activates or increases the frequency, rate or extent of CoA-transferase activity.	tmpzr1t_l9r_go_relaxed.owl	activation of CoA-transferase activity|upregulation of CoA-transferase activity|up regulation of CoA-transferase activity|up-regulation of CoA-transferase activity							bc	2017-02-08T13:01:04Z					biological_process											owl:Class	
GO:1905918	biolink:NamedThing	regulation of CoA-transferase activity	Any process that modulates the frequency, rate or extent of CoA-transferase activity.	tmpzr1t_l9r_go_relaxed.owl								bc	2017-02-08T13:00:48Z					biological_process											owl:Class	
GO:0035807	biolink:NamedThing	positive regulation of blood coagulation in other organism	Any process in which an organism activates, maintains or increases the frequency, rate or extent of blood coagulation in another organism. Blood coagulation is the sequential process in which the multiple coagulation factors of the blood interact, ultimately resulting in the formation of an insoluble fibrin clot.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of blood clotting in other organism|positive regulation by organism of blood clotting in other organism|positive regulation by organism of blood coagulation in other organism							bf	2011-04-20T11:43:37Z					biological_process											owl:Class	
GO:0035806	biolink:NamedThing	modulation of blood coagulation in other organism	Any process in which an organism modulates the frequency, rate or extent of blood coagulation in another organism. Blood coagulation is the sequential process in which the multiple coagulation factors of the blood interact, ultimately resulting in the formation of an insoluble fibrin clot.	tmpzr1t_l9r_go_relaxed.owl	modulation by organism of blood clotting in other organism|regulation of blood coagulation in other organism|regulation by organism of blood clotting in other organism|regulation of blood clotting in other organism|modulation by organism of blood coagulation in other organism							bf	2011-04-20T11:38:49Z					biological_process											owl:Class	
GO:0048215	biolink:NamedThing	positive regulation of Golgi vesicle fusion to target membrane	Any process that activates or increases the frequency, rate or extent of Golgi vesicle fusion to target membrane.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of Golgi vesicle fusion to target membrane|stimulation of Golgi vesicle fusion to target membrane|activation of Golgi vesicle fusion to target membrane|up regulation of Golgi vesicle fusion to target membrane|upregulation of Golgi vesicle fusion to target membrane													biological_process											owl:Class	
GO:0031340	biolink:NamedThing	positive regulation of vesicle fusion	Any process that activates or increases the frequency, rate or extent of vesicle fusion.	tmpzr1t_l9r_go_relaxed.owl	activation of vesicle fusion|up regulation of vesicle fusion|upregulation of vesicle fusion|stimulation of vesicle fusion|up-regulation of vesicle fusion													biological_process											owl:Class	
GO:0052702	biolink:NamedThing	cellular modified histidine catabolic process	The chemical reactions and pathways resulting in the breakdown of compounds derived from histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid.	tmpzr1t_l9r_go_relaxed.owl	cellular histidine derivative catabolic process|histidine derivative catabolic process|cellular modified histidine degradation|modified histidine catabolic process|cellular histidine derivative degradation|modified histidine catabolism|cellular histidine derivative breakdown|cellular modified histidine catabolism|cellular modified histidine breakdown|cellular histidine derivative catabolism							ai	2011-08-01T03:48:41Z					biological_process											owl:Class	
GO:0071547	biolink:NamedThing	piP-body	A P granule that contains the PIWIL4-TDRD9 module, a set of proteins that act in the secondary piRNA pathway.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-01-12T05:47:47Z					cellular_component											owl:Class	
GO:0019095	biolink:NamedThing	pole plasm mitochondrial rRNA localization	Any process in which mitochondrial ribosomal RNA is transported to, or maintained in, the oocyte pole plasm. An example of this is found in Drosophila melanogaster.	tmpzr1t_l9r_go_relaxed.owl	establishment and maintenance of mitochondrial rRNA localization in pole plasm|pole plasm mitochondrial rRNA localisation|oocyte pole plasm mitochondrial rRNA localization											GO:0048117		biological_process											owl:Class	
GO:0007316	biolink:NamedThing	pole plasm RNA localization	Any process in which RNA is transported to, or maintained in, the oocyte pole plasm. An example of this is found in Drosophila melanogaster.	tmpzr1t_l9r_go_relaxed.owl	oocyte pole plasm RNA localization|establishment and maintenance of pole plasm RNA localization|pole plasm RNA localisation											GO:0048116		biological_process											owl:Class	
GO:0102956	biolink:NamedThing	UDP-glucose:sinapaldehyde 4-beta-D-glucosyltransferase activity	Catalysis of the reaction: UDP-alpha-D-glucose + sinapoyl aldehyde = H+ + sinapaldehyde glucoside + UDP.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-92|RHEA:57712									molecular_function											owl:Class	
GO:1905837	biolink:NamedThing	cellular response to triterpenoid	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a triterpenoid stimulus.	tmpzr1t_l9r_go_relaxed.owl								sl	2017-01-17T19:37:44Z					biological_process											owl:Class	
GO:0071396	biolink:NamedThing	cellular response to lipid	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipid stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-12-11T04:37:10Z					biological_process											owl:Class	
GO:0044062	biolink:NamedThing	regulation of excretion	Any process that modulates the frequency, rate, or extent of excretion, the elimination by an organism of the waste products that arise as a result of metabolic activity.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0031078	biolink:NamedThing	histone deacetylase activity (H3-K14 specific)	Catalysis of the reaction: histone H3 N6-acetyl-L-lysine (position 14) + H2O = histone H3 L-lysine (position 14) + acetate. This reaction represents the removal of an acetyl group from lysine at position 14 of the histone H3 protein.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0004407	biolink:NamedThing	histone deacetylase activity	Catalysis of the reaction: histone N6-acetyl-L-lysine + H2O = histone L-lysine + acetate. This reaction represents the removal of an acetyl group from a histone, a class of proteins complexed to DNA in chromatin and chromosomes.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/22295			Reactome:R-HSA-3782637|Reactome:R-HSA-2545203|Reactome:R-HSA-3782655|Reactome:R-HSA-433672|RHEA:58196|Reactome:R-HSA-3777129|Reactome:R-HSA-6805650|Reactome:R-HSA-3769447|Reactome:R-HSA-2545253|MetaCyc:3.5.1.98-RXN|EC:3.5.1.98|Reactome:R-HSA-427514									molecular_function											owl:Class	
GO:1903454	biolink:NamedThing	regulation of androst-4-ene-3,17-dione biosynthetic process	Any process that modulates the frequency, rate or extent of androst-4-ene-3,17-dione biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of androstenedione biosynthetic process|regulation of androst-4-ene-3,17-dione biosynthesis|regulation of androst-4-ene-3,17-dione synthesis|regulation of androst-4-ene-3,17-dione formation|regulation of androst-4-ene-3,17-dione anabolism							mr	2014-09-22T14:36:50Z					biological_process											owl:Class	
GO:0010566	biolink:NamedThing	regulation of ketone biosynthetic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of a ketone, carried out by individual cells.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1904263	biolink:NamedThing	positive regulation of TORC1 signaling	Any process that activates or increases the frequency, rate or extent of TORC1 signaling.	tmpzr1t_l9r_go_relaxed.owl	up regulation of TORC1 signal transduction|up-regulation of TORC1 signaling|activation of TORC1 signal transduction|activation of TORC1 signaling|positive regulation of TORC1 signal transduction|upregulation of TORC1 signal transduction|upregulation of TORC1 signaling|up-regulation of TORC1 signal transduction|up regulation of TORC1 signaling							lb	2015-05-27T13:13:10Z					biological_process											owl:Class	
GO:0032008	biolink:NamedThing	positive regulation of TOR signaling	Any process that activates or increases the frequency, rate or extent of TOR signaling.	tmpzr1t_l9r_go_relaxed.owl	activation of TOR signaling pathway|positive regulation of TOR signaling cascade|up-regulation of TOR signaling pathway|stimulation of TOR signaling pathway|upregulation of TOR signaling pathway|positive regulation of target of rapamycin signalling pathway|up regulation of TOR signaling pathway|positive regulation of TOR signaling pathway|positive regulation of target of rapamycin signaling pathway|positive regulation of TOR signalling pathway													biological_process											owl:Class	
GO:0061546	biolink:NamedThing	tyramine secretion, neurotransmission	The regulated release of a tyramine by a cell in which the tyramine acts as a neurotransmitter.	tmpzr1t_l9r_go_relaxed.owl								dph	2013-06-25T09:16:47Z					biological_process											owl:Class	
GO:0061532	biolink:NamedThing	primary amine secretion, neurotransmission	The regulated release of a primary amine by a cell, in which the primary amine acts as a neurotransmitter.	tmpzr1t_l9r_go_relaxed.owl								dph	2013-06-21T15:57:12Z					biological_process											owl:Class	
GO:0050908	biolink:NamedThing	detection of light stimulus involved in visual perception	The series of events involved in visual perception in which a light stimulus is received and converted into a molecular signal.	tmpzr1t_l9r_go_relaxed.owl	visual perception, sensory transduction of light stimulus|sensory transduction of light during visual perception|sensory transduction of light stimulus during visual perception|visual perception, sensory transduction during perception of light|visual perception, detection of light stimulus|sensory detection of light during visual perception|sensory detection of light stimulus during visual perception													biological_process											owl:Class	
GO:0050962	biolink:NamedThing	detection of light stimulus involved in sensory perception	The series of events in which a light stimulus is received by a cell and converted into a molecular signal as part of the sensory perception of light.	tmpzr1t_l9r_go_relaxed.owl	sensory perception, sensory detection of light stimulus|sensory transduction of light stimulus during sensory perception|sensory detection of light stimulus during sensory perception|sensory perception, sensory transduction of light stimulus|sensory transduction of light stimulus|sensory detection of light stimulus													biological_process											owl:Class	
GO:0051169	biolink:NamedThing	nuclear transport	The directed movement of substances into, out of, or within the nucleus.	tmpzr1t_l9r_go_relaxed.owl	nucleus transport				Wikipedia:Nuclear_transport									biological_process											owl:Class	
GO:0035157	biolink:NamedThing	negative regulation of fusion cell fate specification	Any process that restricts, stops or prevents a cell from adopting a fusion cell fate. Once the terminal and fusion fates have been correctly induced, inhibitory feedback loops prevent the remaining branch cells from assuming similar fates.	tmpzr1t_l9r_go_relaxed.owl	downregulation of fusion cell fate specification|inhibition of fusion cell fate specification|down regulation of fusion cell fate specification|down-regulation of fusion cell fate specification													biological_process											owl:Class	
GO:0009996	biolink:NamedThing	negative regulation of cell fate specification	Any process that restricts, stops or prevents a cell from adopting a specific cell fate.	tmpzr1t_l9r_go_relaxed.owl	suppression of cell fate|down regulation of cell fate specification|down-regulation of cell fate specification|downregulation of cell fate specification|inhibition of cell fate specification													biological_process											owl:Class	
GO:0071203	biolink:NamedThing	WASH complex	A protein complex that localizes at the surface of endosomes, where it recruits and activates the Arp2/3 complex to induce actin polymerization. In human, the WASH complex is composed of F-actin-capping protein subunits alpha and beta, WASH1, FAM21, KIAA1033, KIAA0196 and CCDC53.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-11-25T11:01:33Z					cellular_component											owl:Class	
GO:0061013	biolink:NamedThing	regulation of mRNA catabolic process	Any process that modulates the rate, frequency, or extent of a mRNA catabolic process, the chemical reactions and pathways resulting in the breakdown of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage.	tmpzr1t_l9r_go_relaxed.owl	regulation of mRNA decay							dph	2010-01-29T01:48:10Z					biological_process											owl:Class	
GO:1903311	biolink:NamedThing	regulation of mRNA metabolic process	Any process that modulates the frequency, rate or extent of mRNA metabolic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of mRNA metabolism							vw	2014-08-18T11:52:26Z					biological_process											owl:Class	
GO:1904527	biolink:NamedThing	negative regulation of microtubule binding	Any process that stops, prevents or reduces the frequency, rate or extent of microtubule binding.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of microtubule/chromatin interaction|inhibition of microtubule severing activity|downregulation of microtubule severing activity|inhibition of microtubule binding|down regulation of microtubule severing activity|down regulation of microtubule/chromatin interaction|down-regulation of microtubule severing activity|down regulation of microtubule binding|negative regulation of microtubule/chromatin interaction|inhibition of microtubule/chromatin interaction|down-regulation of microtubule binding|downregulation of microtubule binding|downregulation of microtubule/chromatin interaction|negative regulation of microtubule severing activity							als	2015-07-30T10:32:29Z					biological_process											owl:Class	
GO:1904526	biolink:NamedThing	regulation of microtubule binding	Any process that modulates the frequency, rate or extent of microtubule binding.	tmpzr1t_l9r_go_relaxed.owl	regulation of microtubule/chromatin interaction|regulation of microtubule severing activity							als	2015-07-30T10:32:13Z					biological_process											owl:Class	
GO:0018417	biolink:NamedThing	iron incorporation into iron-sulfur cluster via tris-L-cysteinyl L-cysteine persulfido L-glutamato L-histidino L-serinyl nickel triiron disulfide trioxide	The incorporation of iron into a 3Fe-2S cluster by tris-L-cysteinyl L-cysteine persulfido L-glutamato L-histidino L-serinyl nickel triiron disulfide trioxide.	tmpzr1t_l9r_go_relaxed.owl	iron incorporation into iron-sulphur cluster via tris-L-cysteinyl L-cysteine persulphido L-glutamato L-histidino L-serinyl nickel triiron disulphide trioxide				RESID:AA0293									biological_process											owl:Class	
GO:0018200	biolink:NamedThing	peptidyl-glutamic acid modification	The modification of peptidyl-glutamic acid.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0048928	biolink:NamedThing	posterior lateral line ganglion neuron differentiation	The process in which a relatively unspecialized cell acquires specialized features of a neuron of the posterior lateral line ganglion.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0048891	biolink:NamedThing	lateral line ganglion neuron differentiation	The process in which a relatively unspecialized cell acquires specialized features of a lateral line ganglion neuron.	tmpzr1t_l9r_go_relaxed.owl	gLL neuron differentiation													biological_process											owl:Class	
GO:0075289	biolink:NamedThing	aplanospore formation	The process in which a nonmotile, asexual spore is formed within a cell in certain algae and fungi (commonly in the Phycomycetes), the wall of aplanospore is distinct from that of the parent cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0034300	biolink:NamedThing	sporangiospore formation	The process in which sporangiospores, a type of asexual spore found in fungi, are formed. Sporangiospores are formed within sac-like structure, the sporangium, following the division of the cytoplasm.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:2000303	biolink:NamedThing	regulation of ceramide biosynthetic process	Any process that modulates the frequency, rate or extent of a ceramide biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of ceramide formation|regulation of ceramide anabolism|regulation of ceramide synthesis|regulation of ceramide biosynthesis							dph	2011-01-04T02:37:12Z					biological_process											owl:Class	
GO:2000899	biolink:NamedThing	xyloglucan catabolic process	The chemical reactions and pathways resulting in the breakdown of a xyloglucan.	tmpzr1t_l9r_go_relaxed.owl	xyloglucan catabolism							jl	2011-07-28T02:52:33Z					biological_process											owl:Class	
GO:0010411	biolink:NamedThing	xyloglucan metabolic process	The chemical reactions and pathways involving xyloglucan, the cross-linking glycan composed of (1->4)-beta-D-glucan backbone substituted at regular intervals with beta-D-xylosyl-(1->6) residues, which is present in the primary cell wall of most higher plants.	tmpzr1t_l9r_go_relaxed.owl	xyloglucan metabolism													biological_process											owl:Class	
GO:1905494	biolink:NamedThing	negative regulation of G-quadruplex DNA binding	Any process that stops, prevents or reduces the frequency, rate or extent of G-quadruplex DNA binding.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of G-quartet DNA binding|inhibition of G-quartet DNA binding|negative regulation of G-DNA binding|inhibition of G-DNA binding|inhibition of tetraplex DNA binding|downregulation of quadruplex DNA binding|down regulation of tetraplex DNA binding|down-regulation of G-quadruplex DNA binding|downregulation of G-DNA binding|down-regulation of quadruplex DNA binding|down regulation of G-DNA binding|down regulation of quadruplex DNA binding|negative regulation of quadruplex DNA binding|down regulation of G quadruplex DNA binding|down-regulation of G-DNA binding|negative regulation of G-quartet DNA binding|inhibition of quadruplex DNA binding|inhibition of G quartet DNA binding|down regulation of G-quartet DNA binding|negative regulation of G quadruplex DNA binding|down-regulation of tetraplex DNA binding|downregulation of G-quartet DNA binding|negative regulation of tetraplex DNA binding|downregulation of tetraplex DNA binding|negative regulation of G quartet DNA binding|inhibition of G quadruplex DNA binding|downregulation of G-quadruplex DNA binding|down regulation of G-quadruplex DNA binding|downregulation of G quadruplex DNA binding|inhibition of G-quadruplex DNA binding|down-regulation of G quadruplex DNA binding|down regulation of G quartet DNA binding|down-regulation of G quartet DNA binding|downregulation of G quartet DNA binding							ans	2016-09-26T14:53:29Z					biological_process											owl:Class	
GO:0010851	biolink:NamedThing	cyclase regulator activity	Binds to and modulates the activity of an enzyme that catalyzes a ring closure reaction.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0030234	biolink:NamedThing	enzyme regulator activity	Binds to and modulates the activity of an enzyme.	tmpzr1t_l9r_go_relaxed.owl	catalytic regulator activity|enzyme modulator|metalloenzyme regulator activity					This term should only be used in cases when the regulator directly interacts with the enzyme.						GO:0010576		molecular_function											owl:Class	
GO:0048094	biolink:NamedThing	male pigmentation	Establishment of a pattern of pigment in males.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0048071	biolink:NamedThing	sex-specific pigmentation	Establishment of a pattern of pigment in one sex that is not observed in the other sex.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0030096	biolink:NamedThing	plasma membrane-derived thylakoid photosystem II	A protein complex, located in the membrane-derived thylakoid, containing the P680 reaction center. In the light, PSII functions as a water-plastoquinone oxidoreductase, transferring electrons from water to plastoquinone.	tmpzr1t_l9r_go_relaxed.owl	plasma membrane photosystem II													cellular_component											owl:Class	
GO:0072755	biolink:NamedThing	cellular response to benomyl	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a benomyl stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2012-11-07T12:06:58Z					biological_process											owl:Class	
GO:0010527	biolink:NamedThing	positive regulation of transposition, RNA-mediated	Any process that increases the frequency, rate or extent of RNA-mediated transposition. RNA-mediated transposition is a type of transpositional recombination which occurs via an RNA intermediate.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0010530	biolink:NamedThing	positive regulation of transposition	Any process that increases the frequency, rate or extent of transposition. Transposition results in the movement of discrete segments of DNA between nonhomologous sites.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0031139	biolink:NamedThing	positive regulation of conjugation with cellular fusion	Any process that increases the rate or frequency of conjugation with cellular fusion.	tmpzr1t_l9r_go_relaxed.owl	activation of conjugation with cellular fusion|stimulation of conjugation with cellular fusion|upregulation of conjugation with cellular fusion|up-regulation of conjugation with cellular fusion|up regulation of conjugation with cellular fusion													biological_process											owl:Class	
GO:0031136	biolink:NamedThing	positive regulation of conjugation	Any process that increases the rate or frequency of conjugation.	tmpzr1t_l9r_go_relaxed.owl	activation of conjugation|upregulation of conjugation|stimulation of conjugation|up regulation of conjugation|up-regulation of conjugation													biological_process											owl:Class	
GO:0090211	biolink:NamedThing	positive regulation of establishment of blood-brain barrier	Any process that increases the rate, frequency or extent of the establishment of the blood-brain barrier, a selectively permeable structural and functional barrier that exists between the capillaries and the brain.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of establishment of BBB							tb	2009-12-23T12:15:53Z					biological_process											owl:Class	
GO:0051240	biolink:NamedThing	positive regulation of multicellular organismal process	Any process that activates or increases the frequency, rate or extent of an organismal process, any of the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of multicellular organismal process|activation of multicellular organismal process|stimulation of multicellular organismal process|up regulation of multicellular organismal process|upregulation of multicellular organismal process													biological_process											owl:Class	
GO:0140454	biolink:NamedThing	protein aggregate center assembly	The reversible aggregation of misfolded proteins and chaperones, formed to shield thermosensitive proteins from degradation until conditions allow disaggregation and refolding.	tmpzr1t_l9r_go_relaxed.owl	protein aggregate centre assembly|PAC assembly|protein aggregate center formation	https://github.com/geneontology/go-ontology/issues/19172						pg	2020-04-20T15:43:52Z					biological_process											owl:Class	
GO:0022607	biolink:NamedThing	cellular component assembly	The aggregation, arrangement and bonding together of a cellular component.	tmpzr1t_l9r_go_relaxed.owl	cell structure assembly|cellular component assembly at cellular level											GO:0071844		biological_process											owl:Class	
GO:0048088	biolink:NamedThing	regulation of male pigmentation	Any process that modulates the frequency, rate or extent of establishment of a pattern of pigment in males.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0062093	biolink:NamedThing	lysophagy	The selective autophagy process in which a damaged lysosome is degraded by macroautophagy.	tmpzr1t_l9r_go_relaxed.owl								dph	2018-11-20T16:47:11Z					biological_process											owl:Class	
GO:0061912	biolink:NamedThing	selective autophagy	The macroautophagy process in which specific structures are targeted by the autophagy process.	tmpzr1t_l9r_go_relaxed.owl								dph	2017-07-07T17:27:37Z					biological_process											owl:Class	
GO:0042100	biolink:NamedThing	B cell proliferation	The expansion of a B cell population by cell division. Follows B cell activation.	tmpzr1t_l9r_go_relaxed.owl	B lymphocyte proliferation|B-lymphocyte proliferation|B-cell proliferation											GO:0042114		biological_process											owl:Class	
GO:0042113	biolink:NamedThing	B cell activation	The change in morphology and behavior of a mature or immature B cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.	tmpzr1t_l9r_go_relaxed.owl	B-cell activation|B lymphocyte activation|B-lymphocyte activation													biological_process											owl:Class	
GO:0015067	biolink:NamedThing	amidinotransferase activity	Catalysis of the reversible transfer of an amidino group to an acceptor.	tmpzr1t_l9r_go_relaxed.owl	transamidinase activity				EC:2.1.4.-									molecular_function											owl:Class	
GO:0016741	biolink:NamedThing	transferase activity, transferring one-carbon groups	Catalysis of the transfer of a one-carbon group from one compound (donor) to another (acceptor).	tmpzr1t_l9r_go_relaxed.owl	methyltransferase activity	https://github.com/geneontology/go-ontology/issues/20486			EC:2.1.-.-									molecular_function											owl:Class	
GO:1901218	biolink:NamedThing	negative regulation of holin activity	Any process that stops, prevents or reduces the frequency, rate or extent of holin activity.	tmpzr1t_l9r_go_relaxed.owl	inhibition of holin activity|down-regulation of holin activity|downregulation of holin activity|antiholin activity|down regulation of holin activity|phage antiholin							bf	2012-08-06T10:48:00Z					biological_process											owl:Class	
GO:0032410	biolink:NamedThing	negative regulation of transporter activity	Any process that stops or reduces the activity of a transporter.	tmpzr1t_l9r_go_relaxed.owl	downregulation of transporter activity|down-regulation of transporter activity|down regulation of transporter activity|inhibition of transporter activity													biological_process											owl:Class	
GO:0044634	biolink:NamedThing	negative regulation of complement activation, alternative pathway in other organism	Any process that stops, prevents, or reduces the frequency, rate or extent of complement activation by the alternative pathway, in a different organism.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-07-05T04:32:55Z					biological_process											owl:Class	
GO:0044633	biolink:NamedThing	modulation of complement activation, alternative pathway in other organism	A process that modulates the frequency, rate or extent of complement activation, via the alternative pathway, in a different organism.	tmpzr1t_l9r_go_relaxed.owl	regulation of complement activation, alternative pathway in other organism							jl	2012-07-05T04:24:08Z					biological_process											owl:Class	
GO:0061981	biolink:NamedThing	3-hydroxykynureninase activity	Catalysis of the reaction: L-3-hydroxykynurenine + H2O = 3-hydroxyanthranilate + L-alanine.	tmpzr1t_l9r_go_relaxed.owl					RHEA:25143			dph	2018-02-14T16:12:49Z					molecular_function											owl:Class	
GO:0045834	biolink:NamedThing	positive regulation of lipid metabolic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving lipids.	tmpzr1t_l9r_go_relaxed.owl	activation of lipid metabolic process|up-regulation of lipid metabolic process|up regulation of lipid metabolic process|positive regulation of lipid metabolism|stimulation of lipid metabolic process|upregulation of lipid metabolic process													biological_process											owl:Class	
GO:0052751	biolink:NamedThing	GDP-mannose hydrolase activity	Catalysis of the reaction: GDP-mannose + H2O = GMP + mannose-1-phosphate.	tmpzr1t_l9r_go_relaxed.owl	GDP-mannose pyrophosphatase activity							ai	2011-09-21T04:11:30Z					molecular_function											owl:Class	
GO:0062043	biolink:NamedThing	positive regulation of cardiac epithelial to mesenchymal transition	Any process that starts or increases the rate, frequency or extent of cardiac epithelial to mesenchymal transition, a transition where a cardiac epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell.	tmpzr1t_l9r_go_relaxed.owl								dph	2018-05-10T18:15:54Z					biological_process											owl:Class	
GO:1901940	biolink:NamedThing	(-)-exo-alpha-bergamotene biosynthetic process	The chemical reactions and pathways resulting in the formation of (-)-exo-alpha-bergamotene.	tmpzr1t_l9r_go_relaxed.owl	(-)-exo-alpha-bergamotene synthesis|(-)-exo-alpha-bergamotene biosynthesis|(-)-exo-alpha-bergamotene anabolism|(-)-exo-alpha-bergamotene formation							ms	2013-02-18T14:55:32Z					biological_process											owl:Class	
GO:0034603	biolink:NamedThing	pyruvate dehydrogenase [NAD(P)+] activity	Catalysis of the reaction: pyruvate + CoA + NAD(P)+ = acetyl-CoA + CO2 + NAD(P)H.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0004738	biolink:NamedThing	pyruvate dehydrogenase activity	Catalysis of the oxidative decarboxylation of pyruvate.	tmpzr1t_l9r_go_relaxed.owl	pyruvic acid dehydrogenase activity|pyruvic dehydrogenase activity				MetaCyc:PYRUVOXID-RXN|MetaCyc:RXN0-1134|Reactome:R-HSA-71397									molecular_function											owl:Class	
GO:0019335	biolink:NamedThing	3-methylquinoline catabolic process	The chemical reactions and pathways resulting in the breakdown of 3-methylquinoline, C10H9N, an aromatic compound composed of a benzene ring and a heterocyclic N-containing ring.	tmpzr1t_l9r_go_relaxed.owl	3-methylquinoline degradation|3-methylquinoline breakdown|3-methylquinoline catabolism				MetaCyc:PWY-721									biological_process											owl:Class	
GO:0006216	biolink:NamedThing	cytidine catabolic process	The chemical reactions and pathways resulting in the breakdown of cytidine, cytosine riboside, a widely distributed nucleoside.	tmpzr1t_l9r_go_relaxed.owl	cytidine catabolism|cytidine breakdown|cytidine degradation													biological_process											owl:Class	
GO:0046087	biolink:NamedThing	cytidine metabolic process	The chemical reactions and pathways involving cytidine, cytosine riboside, a widely distributed nucleoside.	tmpzr1t_l9r_go_relaxed.owl	cytidine metabolism													biological_process											owl:Class	
GO:0015931	biolink:NamedThing	nucleobase-containing compound transport	The directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	nucleobase, nucleoside, nucleotide and nucleic acid transport													biological_process											owl:Class	
GO:0071705	biolink:NamedThing	nitrogen compound transport	The directed movement of nitrogen-containing compounds into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-03-08T03:56:28Z					biological_process											owl:Class	
GO:0090381	biolink:NamedThing	regulation of heart induction	Any process that modulates the rate, frequency, or extent of heart induction. Heart induction is the close range interaction between mesoderm and endoderm or ectoderm that causes cells to change their fates and specify the development of the heart.	tmpzr1t_l9r_go_relaxed.owl								tb	2010-10-04T10:23:43Z					biological_process											owl:Class	
GO:0033088	biolink:NamedThing	negative regulation of immature T cell proliferation in thymus	Any process that stops, prevents, or reduces the frequency, rate or extent of immature T cell proliferation in the thymus.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of thymocyte proliferation|negative regulation of thymic T cell proliferation|negative regulation of thymocyte cell proliferation													biological_process											owl:Class	
GO:0033087	biolink:NamedThing	negative regulation of immature T cell proliferation	Any process that stops, prevents, or reduces the frequency, rate or extent of immature T cell proliferation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:2000424	biolink:NamedThing	positive regulation of eosinophil chemotaxis	Any process that activates or increases the frequency, rate or extent of eosinophil chemotaxis.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-02-24T01:17:35Z					biological_process											owl:Class	
GO:2000422	biolink:NamedThing	regulation of eosinophil chemotaxis	Any process that modulates the frequency, rate or extent of eosinophil chemotaxis.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-02-24T01:16:44Z					biological_process											owl:Class	
GO:0042198	biolink:NamedThing	nylon metabolic process	The chemical reactions and pathways involving nylon, a polymer where the main polymer chain comprises recurring amide groups; these compounds are generally formed from combinations of diamines, diacids and amino acids.	tmpzr1t_l9r_go_relaxed.owl	nylon metabolism													biological_process											owl:Class	
GO:0000758	biolink:NamedThing	agglutination involved in conjugation with mutual genetic exchange	The aggregation or adhesion of compatible mating types via complementary cell-cell interactions during conjugation without cellular fusion of a unicellular organism.	tmpzr1t_l9r_go_relaxed.owl	sexual flocculation|agglutination involved in conjugation without cellular fusion													biological_process											owl:Class	
GO:0000771	biolink:NamedThing	agglutination involved in conjugation	The aggregation or adhesion of compatible mating types via complementary cell-cell interactions prior to the formation of irreversible cellular contacts during conjugation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1903299	biolink:NamedThing	regulation of hexokinase activity	Any process that modulates the frequency, rate or extent of hexokinase activity.	tmpzr1t_l9r_go_relaxed.owl	regulation of hexokinase (phosphorylating)|regulation of hexokinase D|regulation of ATP-dependent hexokinase activity|regulation of hexokinase type III activity|regulation of hexokinase type IV glucokinase activity|regulation of hexokinase type II activity|regulation of hexokinase type IV|regulation of hexokinase type IV (glucokinase) activity|regulation of glucose ATP phosphotransferase activity|regulation of hexokinase type I activity|regulation of ATP:D-hexose 6-phosphotransferase activity							mr	2014-08-15T23:17:53Z					biological_process											owl:Class	
GO:0043549	biolink:NamedThing	regulation of kinase activity	Any process that modulates the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0060376	biolink:NamedThing	positive regulation of mast cell differentiation	Any process that increases the rate, frequency or extent of mast cell differentiation, the process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of a mast cell. A mast cell is a cell that is found in almost all tissues containing numerous basophilic granules and capable of releasing large amounts of histamine and heparin upon activation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0060375	biolink:NamedThing	regulation of mast cell differentiation	Any process that modulates the rate, frequency or extent of mast cell differentiation, the process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of a mast cell. A mast cell is a cell that is found in almost all tissues containing numerous basophilic granules and capable of releasing large amounts of histamine and heparin upon activation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1900070	biolink:NamedThing	negative regulation of cellular hyperosmotic salinity response	Any process that stops, prevents or reduces the frequency, rate or extent of cellular hyperosmotic salinity response.	tmpzr1t_l9r_go_relaxed.owl	inhibition of cellular response to hyperosmotic salt stress|inhibition of cellular hyperosmotic salinity response|down-regulation of cellular response to hyperosmotic salt stress|downregulation of cellular response to hyperosmotic salt stress|down-regulation of cellular hyperosmotic salinity response|negative regulation of cellular response to hyperosmotic salt stress|down regulation of cellular hyperosmotic salinity response|downregulation of cellular hyperosmotic salinity response|down regulation of cellular response to hyperosmotic salt stress							pr	2012-01-26T02:45:43Z					biological_process											owl:Class	
GO:1901001	biolink:NamedThing	negative regulation of response to salt stress	Any process that stops, prevents or reduces the frequency, rate or extent of response to salt stress.	tmpzr1t_l9r_go_relaxed.owl	downregulation of response to ionic osmotic stress|inhibition of response to ionic osmotic stress|inhibition of response to salt stress|downregulation of salinity response|down-regulation of response to ionic osmotic stress|down regulation of response to salt stress|downregulation of response to salt stress|negative regulation of response to ionic osmotic stress|down-regulation of response to salt stress|down regulation of salinity response|down regulation of response to ionic osmotic stress|inhibition of salinity response|negative regulation of salinity response|down-regulation of salinity response							dhl	2012-06-14T05:41:43Z					biological_process											owl:Class	
GO:1903109	biolink:NamedThing	positive regulation of mitochondrial transcription	Any process that activates or increases the frequency, rate or extent of transcription occuring in the mitochondrion.	tmpzr1t_l9r_go_relaxed.owl	up regulation of mitochondrial transcription|activation of transcription from mitochondrial promoter|upregulation of transcription from mitochondrial promoter|upregulation of mitochondrial transcription|up-regulation of transcription from mitochondrial promoter|activation of mitochondrial transcription|up-regulation of mitochondrial transcription|positive regulation of transcription from mitochondrial promoter|up regulation of transcription from mitochondrial promoter							al	2014-06-09T11:53:20Z					biological_process											owl:Class	
GO:1903108	biolink:NamedThing	regulation of mitochondrial transcription	Any process that modulates the frequency, rate or extent of transcription occuring in the mitochondrion.	tmpzr1t_l9r_go_relaxed.owl	regulation of transcription from mitochondrial promoter							al	2014-06-09T11:53:14Z					biological_process											owl:Class	
GO:1903832	biolink:NamedThing	regulation of cellular response to amino acid starvation	Any process that modulates the frequency, rate or extent of cellular response to amino acid starvation.	tmpzr1t_l9r_go_relaxed.owl								rn	2015-01-21T18:44:28Z					biological_process											owl:Class	
GO:0061534	biolink:NamedThing	gamma-aminobutyric acid secretion, neurotransmission	The regulated release of gamma-aminobutyric acid by a cell, in which the gamma-aminobutyric acid acts as a neurotransmitter.	tmpzr1t_l9r_go_relaxed.owl								dph	2013-06-21T16:10:50Z					biological_process											owl:Class	
GO:0016987	biolink:NamedThing	sigma factor activity	Sigma factors act as the promoter specificity subunit of eubacterial and plant plastid multisubunit RNA polymerases, whose core subunit composition is often described as alpha(2)-beta-beta-prime. Although sigma does not bind DNA on its own, when combined with the core to form the holoenzyme, the sigma factor binds specifically to promoter elements. The sigma subunit is released once elongation begins.	tmpzr1t_l9r_go_relaxed.owl	core DNA-dependent RNA polymerase binding promoter specificity activity|plastid sigma factor activity|bacterial sigma factor activity|promoter selection factor activity|DNA-dependent RNA polymerase promoter selection factor|sigma transcription factor	https://github.com/geneontology/go-ontology/issues/14848|https://github.com/geneontology/go-ontology/issues/15587						krc	2010-08-11T04:12:24Z			GO:0001053|GO:0000996		molecular_function											owl:Class	
GO:0071226	biolink:NamedThing	cellular response to molecule of fungal origin	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by molecules of fungal origin such as chito-octamer oligosaccharide.	tmpzr1t_l9r_go_relaxed.owl	cellular response to fungus associated molecule							mah	2009-12-03T01:50:01Z					biological_process											owl:Class	
GO:0002238	biolink:NamedThing	response to molecule of fungal origin	Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by molecules of fungal origin such as chito-octamer oligosaccharide.	tmpzr1t_l9r_go_relaxed.owl	response to fungus associated molecule													biological_process											owl:Class	
GO:1900556	biolink:NamedThing	emericellamide catabolic process	The chemical reactions and pathways resulting in the breakdown of emericellamide.	tmpzr1t_l9r_go_relaxed.owl	emericellamide breakdown|emericellamide catabolism|emericellamide degradation							di	2012-05-15T01:33:07Z					biological_process											owl:Class	
GO:1901335	biolink:NamedThing	lactone catabolic process	The chemical reactions and pathways resulting in the breakdown of lactone.	tmpzr1t_l9r_go_relaxed.owl	lactone catabolism|lactone breakdown|lactone degradation							bf	2012-09-03T10:27:11Z					biological_process											owl:Class	
GO:0046512	biolink:NamedThing	sphingosine biosynthetic process	The chemical reactions and pathways resulting in the formation of sphingosine (sphing-4-enine), trans-D-erytho-2-amino-octadec-4-ene-1,3-diol, a long chain amino diol sphingoid base that occurs in most sphingolipids in animal tissues.	tmpzr1t_l9r_go_relaxed.owl	sphingosine anabolism|sphingosine biosynthesis|sphingosine formation|sphingosine synthesis													biological_process											owl:Class	
GO:0046520	biolink:NamedThing	sphingoid biosynthetic process	The chemical reactions and pathways resulting in the formation of sphingoids, any of a class of compounds comprising sphinganine and its homologues and stereoisomers, and derivatives of these compounds.	tmpzr1t_l9r_go_relaxed.owl	sphingoid anabolism|sphingoid synthesis|sphingoid biosynthesis|sphingoid formation													biological_process											owl:Class	
GO:0031382	biolink:NamedThing	mating projection formation	The aggregation, arrangement and bonding together of a set of components to form a cell projection in response to mating pheromone. This process is observed in unicellular fungi.	tmpzr1t_l9r_go_relaxed.owl	shmooing|mating projection biogenesis|mating projection assembly													biological_process											owl:Class	
GO:0120031	biolink:NamedThing	plasma membrane bounded cell projection assembly	Formation of a prolongation or process extending and that is bounded by plasma membrane, e.g. a cilium, lamellipodium, or axon.	tmpzr1t_l9r_go_relaxed.owl	eupodium	https://github.com/geneontology/go-ontology/issues/13298						krc	2017-04-24T23:56:08Z					biological_process											owl:Class	
GO:0004819	biolink:NamedThing	glutamine-tRNA ligase activity	Catalysis of the reaction: ATP + L-glutamine + tRNA(Gln) = AMP + diphosphate + L-glutaminyl-tRNA(Gln).	tmpzr1t_l9r_go_relaxed.owl	glutamine-tRNA synthetase activity|glutaminyl-transfer RNA synthetase activity|glutaminyl ribonucleic acid|L-glutamine:tRNAGln ligase (AMP-forming)|GlnRS|glutaminyl-tRNA synthetase activity|glutaminyl-transfer ribonucleate synthetase activity|glutamine translase activity				Reactome:R-HSA-380241|RHEA:20121|Reactome:R-HSA-379982|EC:6.1.1.18|MetaCyc:GLUTAMINE--TRNA-LIGASE-RXN									molecular_function											owl:Class	
GO:0004788	biolink:NamedThing	thiamine diphosphokinase activity	Catalysis of the reaction: ATP + thiamine = AMP + thiamine diphosphate.	tmpzr1t_l9r_go_relaxed.owl	thiamine pyrophosphokinase activity|thiamin:ATP pyrophosphotransferase activity|thiamin pyrophosphotransferase activity|thiamin diphosphokinase activity|ATP:thiamin pyrophosphotransferase activity|thiaminokinase activity|ATP:thiamine diphosphotransferase activity|TPTase activity|thiamin pyrophosphokinase activity				RHEA:11576|MetaCyc:THIAMIN-PYROPHOSPHOKINASE-RXN|Reactome:R-HSA-196761|EC:2.7.6.2									molecular_function											owl:Class	
GO:0016778	biolink:NamedThing	diphosphotransferase activity	Catalysis of the transfer of a diphosphate group from one compound (donor) to a another (acceptor).	tmpzr1t_l9r_go_relaxed.owl					EC:2.7.6.-									molecular_function											owl:Class	
GO:0050810	biolink:NamedThing	regulation of steroid biosynthetic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus.	tmpzr1t_l9r_go_relaxed.owl	regulation of steroid synthesis|regulation of steroid biosynthesis|regulation of steroid anabolism|regulation of steroid formation|regulation of steroidogenesis													biological_process											owl:Class	
GO:0046890	biolink:NamedThing	regulation of lipid biosynthetic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of lipids.	tmpzr1t_l9r_go_relaxed.owl	regulation of lipid synthesis|regulation of lipid biosynthesis|regulation of lipid formation|regulation of lipid anabolism|regulation of lipogenesis													biological_process											owl:Class	
GO:0008517	biolink:NamedThing	folic acid transmembrane transporter activity	Enables the transfer of folic acid (pteroylglutamic acid) from one side of a membrane to the other. Folic acid is widely distributed as a member of the vitamin B complex and is essential for the synthesis of purine and pyrimidines.	tmpzr1t_l9r_go_relaxed.owl	folate transporter activity|folic acid transporter activity|folate transmembrane transporter activity|vitamin B9 transporter activity|vitamin M transporter activity				Reactome:R-HSA-200729|Reactome:R-HSA-200646|Reactome:R-HSA-200680|Reactome:R-HSA-200652|Reactome:R-HSA-200720									molecular_function											owl:Class	
GO:0072349	biolink:NamedThing	modified amino acid transmembrane transporter activity	Enables the transfer of modified amino acids from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	amino acid derivative transmembrane transporter activity|modified amino acid transporter activity							mah	2010-11-11T11:50:31Z					molecular_function											owl:Class	
GO:0035208	biolink:NamedThing	positive regulation of hemocyte proliferation	Any process that activates or increases the rate or extent of hemocyte proliferation. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) that are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. An example of this process is found in Drosophila melanogaster.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of arthropod blood cell proliferation|upregulation of hemocyte proliferation|up-regulation of hemocyte proliferation|stimulation of hemocyte proliferation|up regulation of hemocyte proliferation|activation of hemocyte proliferation													biological_process											owl:Class	
GO:0008284	biolink:NamedThing	positive regulation of cell population proliferation	Any process that activates or increases the rate or extent of cell proliferation.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of cell proliferation|upregulation of cell proliferation|stimulation of cell proliferation|activation of cell proliferation|up regulation of cell proliferation|positive regulation of cell proliferation													biological_process											owl:Class	
GO:0090343	biolink:NamedThing	positive regulation of cell aging	Any process that increases the rate, frequency, or extent of cell aging. Cell aging is the progression of the cell from its inception to the end of its lifespan.	tmpzr1t_l9r_go_relaxed.owl								tb	2010-06-02T10:12:37Z					biological_process											owl:Class	
GO:0010667	biolink:NamedThing	negative regulation of cardiac muscle cell apoptotic process	Any process that decreases the rate or extent of cardiac cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a cardiac muscle cell and result in its death.	tmpzr1t_l9r_go_relaxed.owl	down regulation of cardiac muscle cell apoptosis|inhibition of cardiac muscle cell apoptosis|down-regulation of cardiac muscle cell apoptosis|negative regulation of cardiac muscle cell apoptosis|downregulation of cardiac muscle cell apoptosis													biological_process											owl:Class	
GO:0010664	biolink:NamedThing	negative regulation of striated muscle cell apoptotic process	Any process that decreases the rate or extent of striated muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a striated muscle cell and result in its death.	tmpzr1t_l9r_go_relaxed.owl	down regulation of striated muscle cell apoptosis|inhibition of striated muscle cell apoptosis|negative regulation of striated muscle cell apoptosis|down-regulation of striated muscle cell apoptosis|downregulation of striated muscle cell apoptosis													biological_process											owl:Class	
GO:1905940	biolink:NamedThing	negative regulation of gonad development	Any process that stops, prevents or reduces the frequency, rate or extent of gonad development.	tmpzr1t_l9r_go_relaxed.owl	down regulation of gonad development|negative regulation of gonadogenesis|downregulation of gonad development|down-regulation of gonad development|down-regulation of gonadogenesis|inhibition of gonad development|downregulation of gonadogenesis|inhibition of gonadogenesis|down regulation of gonadogenesis							hbye	2017-02-09T17:01:59Z					biological_process											owl:Class	
GO:2000242	biolink:NamedThing	negative regulation of reproductive process	Any process that stops, prevents, or reduces the frequency, rate or extent of reproductive process.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-11-10T02:44:05Z					biological_process											owl:Class	
GO:1900767	biolink:NamedThing	fonsecin metabolic process	The chemical reactions and pathways involving fonsecin.	tmpzr1t_l9r_go_relaxed.owl	fonsecin metabolism							di	2012-06-04T09:21:14Z					biological_process											owl:Class	
GO:0014841	biolink:NamedThing	skeletal muscle satellite cell proliferation	The multiplication or reproduction of satellite cells, resulting in the expansion of the cell population. Satellite cells are quiescent cells that are located between the basal lamina and the plasmalemma of the muscle fiber, which are the main contributors to postnatal muscle growth. In adult muscle, satellite cells become activated to divide and differentiate in response to muscle damage.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0014856	biolink:NamedThing	skeletal muscle cell proliferation	The multiplication or reproduction of skeletal muscle cells, resulting in the expansion of a cell population.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1904405	biolink:NamedThing	cellular response to formaldehyde	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a formaldehyde stimulus.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-06-23T21:14:10Z					biological_process											owl:Class	
GO:0110096	biolink:NamedThing	cellular response to aldehyde	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an aldehyde stimulus.	tmpzr1t_l9r_go_relaxed.owl								kmv	2018-02-16T21:29:18Z					biological_process											owl:Class	
GO:1990953	biolink:NamedThing	intramanchette transport	The movement of vesicles and protein complexes carried out by molecular motors, kinesins and dynein, along the microtubule tracks within the manchette and by myosin along actin filaments.	tmpzr1t_l9r_go_relaxed.owl	IMT							krc	2016-05-11T00:17:56Z					biological_process											owl:Class	
GO:0098840	biolink:NamedThing	protein transport along microtubule	The directed movement of a protein along a microtubule, mediated by motor proteins.	tmpzr1t_l9r_go_relaxed.owl	microtubule-based protein transport													biological_process											owl:Class	
GO:0018062	biolink:NamedThing	peptidyl-tryptophan succinylation	The modification of an N-terminal peptidyl-tryptophan residue to form peptidyl-N2-succinyl-L-tryptophan.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0130									biological_process											owl:Class	
GO:0031365	biolink:NamedThing	N-terminal protein amino acid modification	The alteration of the N-terminal amino acid residue in a protein.	tmpzr1t_l9r_go_relaxed.owl	peptide or protein amino-terminal blocking|peptide/protein amino-terminal blocking											GO:0018409		biological_process											owl:Class	
GO:0009847	biolink:NamedThing	spore germination	The physiological and developmental changes that occur in a spore following release from dormancy up to the earliest signs of growth (e.g. emergence from a spore wall).	tmpzr1t_l9r_go_relaxed.owl	spore germination on or near host											GO:0075005		biological_process											owl:Class	
GO:0030154	biolink:NamedThing	cell differentiation	The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Cellular_differentiation									biological_process											owl:Class	
GO:0090360	biolink:NamedThing	platelet-derived growth factor production	The appearance of any platelet-derived growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	tmpzr1t_l9r_go_relaxed.owl						Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.		tb	2010-07-12T10:32:27Z					biological_process											owl:Class	
GO:0001816	biolink:NamedThing	cytokine production	The appearance of a cytokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	tmpzr1t_l9r_go_relaxed.owl	interferon production|cytokine metabolic process|cytokine secretion|interleukin production|cytokine biosynthetic process|interferon secretion|interleukin secretion	https://github.com/geneontology/go-ontology/issues/19116				Note that this term is intended for use when a gene product is seen to cause apparent increases in intracellular or extracellular cytokine levels, without specific regard as to whether the increase is due to increased biosynthesis, increased secretion of preexisting cytokine molecules, or increased conversion from precursor molecules.						GO:0042107|GO:0042089|GO:0050663|GO:0042032		biological_process											owl:Class	
GO:0050382	biolink:NamedThing	uracil-5-carboxylate decarboxylase activity	Catalysis of the reaction: H(+) + uracil 5-carboxylate = CO(2) + uracil.	tmpzr1t_l9r_go_relaxed.owl	uracil-5-carboxylate carboxy-lyase (uracil-forming)|uracil-5-carboxylic acid decarboxylase activity|uracil-5-carboxylate carboxy-lyase activity				EC:4.1.1.66|KEGG_REACTION:R00973|MetaCyc:URACIL-5-CARBOXYLATE-DECARBOXYLASE-RXN|RHEA:17685									molecular_function											owl:Class	
GO:0032764	biolink:NamedThing	negative regulation of mast cell cytokine production	Any process that stops, prevents, or reduces the frequency, rate, or extent of mast cell cytokine production.	tmpzr1t_l9r_go_relaxed.owl	down regulation of mast cell cytokine production|downregulation of mast cell cytokine production|inhibition of mast cell cytokine production|down-regulation of mast cell cytokine production													biological_process											owl:Class	
GO:0106279	biolink:NamedThing	negative regulation of UDP-N-acetylglucosamine biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of the UDP-N-acetylglucosamine biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of UDP-N-acetylglucosamine formation|negative regulation of UDP-N-acetylglucosamine synthesis|negative regulation of UDP-GlcNAc biosynthesis|negative regulation of UDP-N-acetylglucosamine biosynthesis|negative regulation of UDP-N-acetylglucosamine anabolism|negative regulation of UDP-GlcNAc biosynthetic process							hjd	2020-07-09T17:26:06Z					biological_process											owl:Class	
GO:0010563	biolink:NamedThing	negative regulation of phosphorus metabolic process	Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0047709	biolink:NamedThing	bis(2-ethylhexyl)phthalate esterase activity	Catalysis of the reaction: bis(2-ethylhexyl)phthalate + H(2)O = 2-ethylhexan-1-ol + 2-ethylhexyl phthalate + H(+).	tmpzr1t_l9r_go_relaxed.owl	bis(2-ethylhexyl)phthalate acylhydrolase activity|DEHP esterase activity				KEGG_REACTION:R04202|RHEA:15529|MetaCyc:BIS2-ETHYLHEXYLPHTHALATE-ESTERASE-RXN|EC:3.1.1.60									molecular_function											owl:Class	
GO:0052689	biolink:NamedThing	carboxylic ester hydrolase activity	Catalysis of the hydrolysis of a carboxylic ester bond.	tmpzr1t_l9r_go_relaxed.owl	esterase A|serine esterase activity|ali-esterase activity|carboxylic acid esterase activity|procaine esterase activity|carboxylic esterase activity|carboxyesterase activity|carboxyl ester hydrolase activity|B-esterase activity|vitamin A esterase|cocaine esterase activity|nonspecific carboxylesterase activity|carboxylesterase activity|carboxylate esterase activity|esterase B|triacetin esterase|alpha-carboxylesterase activity				Reactome:R-HSA-5693691|EC:3.1.1.1|Reactome:R-HSA-8937442|MetaCyc:CARBOXYLESTERASE-RXN|KEGG_REACTION:R00630|RHEA:21164|Reactome:R-HSA-9619024|UM-BBD_reactionID:r1025							GO:0016789|GO:0004302|GO:0004759|GO:0004091		molecular_function											owl:Class	
GO:0070570	biolink:NamedThing	regulation of neuron projection regeneration	Any process that modulates the rate, frequency or extent of neuron projection regeneration, the regrowth of neuronal processes such as axons or dendrites following their loss or damage.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-04-15T01:23:48Z					biological_process											owl:Class	
GO:0010975	biolink:NamedThing	regulation of neuron projection development	Any process that modulates the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites).	tmpzr1t_l9r_go_relaxed.owl	regulation of neurite formation|regulation of neurite biosynthesis|regulation of neurite growth|regulation of neurite development							tb	2009-06-01T10:44:45Z					biological_process											owl:Class	
GO:0043487	biolink:NamedThing	regulation of RNA stability	Any process that modulates the propensity of RNA molecules to degradation. Includes processes that both stabilize and destabilize RNAs.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0061616	biolink:NamedThing	glycolytic process from fructose through fructose-6-phosphate	The glycolytic process through fructose-6-phosphate in which fructose is catabolized into pyruvate.	tmpzr1t_l9r_go_relaxed.owl	glycolysis from fructose through fructose-6-phosphate				MetaCyc:PWY-5484			dph	2014-04-08T10:20:37Z					biological_process											owl:Class	
GO:0006001	biolink:NamedThing	fructose catabolic process	The chemical reactions and pathways resulting in the breakdown of fructose, the ketohexose arabino-2-hexulose.	tmpzr1t_l9r_go_relaxed.owl	fructose breakdown|fructose catabolism|fructose degradation													biological_process											owl:Class	
GO:1901544	biolink:NamedThing	positive regulation of ent-pimara-8(14),15-diene biosynthetic process	Any process that activates or increases the frequency, rate or extent of ent-pimara-8(14),15-diene biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	upregulation of ent-pimara-8(14),15-diene formation|positive regulation of ent-pimara-8(14),15-diene formation|positive regulation of ent-pimara-8(14),15-diene synthesis|upregulation of ent-pimara-8(14),15-diene biosynthetic process|up regulation of ent-pimara-8(14),15-diene anabolism|up-regulation of ent-pimara-8(14),15-diene formation|up regulation of ent-pimara-8(14),15-diene formation|activation of ent-pimara-8(14),15-diene biosynthesis|upregulation of ent-pimara-8(14),15-diene biosynthesis|upregulation of ent-pimara-8(14),15-diene anabolism|up-regulation of ent-pimara-8(14),15-diene anabolism|positive regulation of ent-pimara-8(14),15-diene biosynthesis|up regulation of ent-pimara-8(14),15-diene biosynthetic process|activation of ent-pimara-8(14),15-diene biosynthetic process|positive regulation of ent-pimara-8(14),15-diene anabolism|up-regulation of ent-pimara-8(14),15-diene biosynthetic process|activation of ent-pimara-8(14),15-diene formation|activation of ent-pimara-8(14),15-diene anabolism|activation of ent-pimara-8(14),15-diene synthesis|upregulation of ent-pimara-8(14),15-diene synthesis|up-regulation of ent-pimara-8(14),15-diene synthesis|up regulation of ent-pimara-8(14),15-diene synthesis|up-regulation of ent-pimara-8(14),15-diene biosynthesis|up regulation of ent-pimara-8(14),15-diene biosynthesis							di	2012-10-26T11:38:07Z					biological_process											owl:Class	
GO:0045828	biolink:NamedThing	positive regulation of isoprenoid metabolic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving isoprenoid.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of isoprenoid metabolic process|stimulation of isoprenoid metabolic process|upregulation of isoprenoid metabolic process|positive regulation of isoprenoid metabolism|activation of isoprenoid metabolic process|up regulation of isoprenoid metabolic process													biological_process											owl:Class	
GO:1990532	biolink:NamedThing	stress response to nickel ion	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis caused by a nickel ion stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to nickel ion stress|response to nickel toxicity|stress response to nickel							kmv	2014-11-07T18:35:31Z					biological_process											owl:Class	
GO:0097501	biolink:NamedThing	stress response to metal ion	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis caused by a metal ion stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to metal ion toxicity|response to metal toxicity|response to metal ion stress|response to excess metal ion							pr	2013-08-15T10:37:45Z					biological_process											owl:Class	
GO:0002927	biolink:NamedThing	archaeosine-tRNA biosynthetic process	The chemical reactions and pathways involved in the biosynthesis of archaeosine, an archaea-specific modified base found at position 15 in the D-loop of certain archaeal tRNAs.	tmpzr1t_l9r_go_relaxed.owl						Archaeosine (7-formamidino-7-deazaguanosine) is a structural variant of the hypermodified nucleoside 7-deazaguanosine. The biosynthesis pathway starts with archaeosine tRNA-guanine transglycosylase (ArcTGT) which catalyzes the exchange of guanine at position 15 in the D-loop of archaeal tRNAs with a free 7-cyano-7-deazaguanine.		hjd	2012-01-18T03:06:27Z					biological_process											owl:Class	
GO:0009058	biolink:NamedThing	biosynthetic process	The chemical reactions and pathways resulting in the formation of substances; typically the energy-requiring part of metabolism in which simpler substances are transformed into more complex ones.	tmpzr1t_l9r_go_relaxed.owl	multicellular organismal biosynthetic process|anabolism|single-organism biosynthetic process|biosynthesis|formation|synthesis				Wikipedia:Anabolism			jl	2012-10-17T15:52:18Z			GO:0044274|GO:0044711		biological_process											owl:Class	
GO:2000780	biolink:NamedThing	negative regulation of double-strand break repair	Any process that stops, prevents or reduces the frequency, rate or extent of double-strand break repair.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-06-23T09:28:08Z					biological_process											owl:Class	
GO:2000779	biolink:NamedThing	regulation of double-strand break repair	Any process that modulates the frequency, rate or extent of double-strand break repair.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-06-23T09:28:02Z					biological_process											owl:Class	
GO:1903726	biolink:NamedThing	negative regulation of phospholipid metabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of phospholipid metabolic process.	tmpzr1t_l9r_go_relaxed.owl	down regulation of phospholipid metabolism|downregulation of phospholipid metabolic process|downregulation of phospholipid metabolism|down-regulation of phospholipid metabolism|inhibition of phospholipid metabolism|down-regulation of phospholipid metabolic process|negative regulation of phospholipid metabolism|inhibition of phospholipid metabolic process|down regulation of phospholipid metabolic process							sl	2014-12-09T20:49:35Z					biological_process											owl:Class	
GO:0045833	biolink:NamedThing	negative regulation of lipid metabolic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving lipids.	tmpzr1t_l9r_go_relaxed.owl	downregulation of lipid metabolic process|negative regulation of lipid metabolism|down regulation of lipid metabolic process|inhibition of lipid metabolic process|down-regulation of lipid metabolic process													biological_process											owl:Class	
GO:0046340	biolink:NamedThing	diacylglycerol catabolic process	The chemical reactions and pathways resulting in the breakdown of diacylglycerol, a glyceride in which any two of the R groups (positions not specified) are acyl groups while the remaining R group can be either H or an alkyl group.	tmpzr1t_l9r_go_relaxed.owl	diacylglycerol degradation|diacylglycerol breakdown|diacylglycerol catabolism|diglyceride catabolism													biological_process											owl:Class	
GO:0046339	biolink:NamedThing	diacylglycerol metabolic process	The chemical reactions and pathways involving diacylglycerol, a glyceride in which any two of the R groups (positions not specified) are acyl groups while the remaining R group can be either H or an alkyl group.	tmpzr1t_l9r_go_relaxed.owl	diacylglycerol metabolism|diglyceride metabolism													biological_process											owl:Class	
GO:0042849	biolink:NamedThing	L-sorbose biosynthetic process	The chemical reactions and pathways resulting in the formation of L-sorbose, the L-enantiomer of the ketohexose xylo-2-hexulose. L-sorbose is formed by bacterial oxidation of sorbitol.	tmpzr1t_l9r_go_relaxed.owl	L-sorbose formation|L-sorbose anabolism|L-sorbose synthesis|L-sorbose biosynthesis													biological_process											owl:Class	
GO:0042847	biolink:NamedThing	sorbose biosynthetic process	The chemical reactions and pathways resulting in the formation of sorbose, the ketohexose xylo-2-hexulose. Sorbose is produced commercially by fermentation and is used as an intermediate in the manufacture of ascorbic acid.	tmpzr1t_l9r_go_relaxed.owl	sorbose formation|sorbose biosynthesis|sorbose anabolism|sorbose synthesis													biological_process											owl:Class	
GO:1904023	biolink:NamedThing	regulation of glucose catabolic process to lactate via pyruvate	Any process that modulates the frequency, rate or extent of glucose catabolic process to lactate via pyruvate.	tmpzr1t_l9r_go_relaxed.owl	regulation of homofermentative lactate fermentation|regulation of homolactate fermentation|regulation of homofermentative pathway|regulation of homolactic fermentation|regulation of glucose fermentation to lactate via pyruvate|regulation of homofermentation							dph	2015-03-11T16:57:32Z					biological_process											owl:Class	
GO:1903578	biolink:NamedThing	regulation of ATP metabolic process	Any process that modulates the frequency, rate or extent of ATP metabolic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of ATP metabolism							sl	2014-10-30T19:04:24Z					biological_process											owl:Class	
GO:0090257	biolink:NamedThing	regulation of muscle system process	Any process that modulates the frequency, rate or extent of a muscle system process, a multicellular organismal process carried out by any of the organs or tissues in a muscle system.	tmpzr1t_l9r_go_relaxed.owl								tb	2010-02-03T11:48:13Z					biological_process											owl:Class	
GO:1990861	biolink:NamedThing	Ubp3-Bre5 deubiquitination complex	A protein complex that cleaves ubiquitin from specific substrates. In the budding yeast Saccharomyces cerevisiae, this complex consists of Ubp3p and Bre5p.	tmpzr1t_l9r_go_relaxed.owl	Ubp3-Bre5 ubiquitin protease complex							rb	2015-09-24T17:56:53Z					cellular_component											owl:Class	
GO:1903811	biolink:NamedThing	L-asparagine import across plasma membrane	The directed movement of L-asparagine from outside of a cell, across the plasma membrane and into the cytosol.	tmpzr1t_l9r_go_relaxed.owl	L-asparagine import into cell|asparagine import							tb	2012-09-24T14:28:58Z			GO:0090469		biological_process											owl:Class	
GO:0015807	biolink:NamedThing	L-amino acid transport	The directed movement of L-enantiomer amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0043763	biolink:NamedThing	UTP:glucose-1-phosphate uridylyltransferase regulator activity	Binds to and modulates the activity of UTP:glucose-1-phosphate uridylyltransferase.	tmpzr1t_l9r_go_relaxed.owl	UDP-glucose pyrophosphorylase regulator activity|UDP-glucose diphosphorylase regulator activity|glucose-1-phosphate uridylyltransferase regulator activity													molecular_function											owl:Class	
GO:1905852	biolink:NamedThing	positive regulation of backward locomotion	Any process that activates or increases the frequency, rate or extent of backward locomotion.	tmpzr1t_l9r_go_relaxed.owl	up regulation of backward locomotion|up-regulation of backward locomotion|upregulation of backward locomotion|activation of backward locomotion							rz	2017-01-23T11:04:25Z					biological_process											owl:Class	
GO:1900347	biolink:NamedThing	positive regulation of methane biosynthetic process from methanethiol	Any process that activates or increases the frequency, rate or extent of methane biosynthetic process from methanethiol.	tmpzr1t_l9r_go_relaxed.owl	upregulation of methane biosynthetic process from methanethiol|up regulation of methane biosynthetic process from methanethiol|activation of methane biosynthetic process from methanethiol|up-regulation of methane biosynthetic process from methanethiol							tt	2012-04-06T02:10:06Z					biological_process											owl:Class	
GO:1901579	biolink:NamedThing	positive regulation of alkane biosynthetic process	Any process that activates or increases the frequency, rate or extent of alkane biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	upregulation of alkane synthesis|up-regulation of alkane biosynthetic process|activation of alkane anabolism|up regulation of alkane biosynthesis|up regulation of alkane formation|up-regulation of alkane formation|positive regulation of alkane biosynthesis|up regulation of alkane anabolism|up-regulation of alkane biosynthesis|positive regulation of alkane synthesis|activation of alkane biosynthetic process|up-regulation of alkane synthesis|upregulation of alkane biosynthesis|upregulation of alkane formation|activation of alkane formation|up regulation of alkane synthesis|activation of alkane synthesis|up regulation of alkane biosynthetic process|activation of alkane biosynthesis|up-regulation of alkane anabolism|positive regulation of alkane formation|positive regulation of alkane anabolism|upregulation of alkane anabolism|upregulation of alkane biosynthetic process							dhl	2012-11-05T21:54:19Z					biological_process											owl:Class	
GO:0032651	biolink:NamedThing	regulation of interleukin-1 beta production	Any process that modulates the frequency, rate, or extent of interleukin-1 beta production.	tmpzr1t_l9r_go_relaxed.owl	regulation of interleukin-1 beta secretion|regulation of interleukin-1 beta biosynthetic process|regulation of IL-1 beta production											GO:0050706|GO:0050722		biological_process											owl:Class	
GO:0032652	biolink:NamedThing	regulation of interleukin-1 production	Any process that modulates the frequency, rate, or extent of interleukin-1 production.	tmpzr1t_l9r_go_relaxed.owl	regulation of interleukin-1 secretion|regulation of IL-1 production|regulation of interleukin-1 biosynthetic process											GO:0050704|GO:0045360		biological_process											owl:Class	
GO:2000731	biolink:NamedThing	negative regulation of termination of RNA polymerase I transcription	Any process that stops, prevents or reduces the frequency, rate or extent of termination of RNA polymerase I transcription.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of transcription termination from RNA polymerase I promoter|negative regulation of transcription termination from Pol I promoter|negative regulation of RNA polymerase I transcription termination							dph	2011-06-10T08:43:44Z					biological_process											owl:Class	
GO:2000730	biolink:NamedThing	regulation of termination of RNA polymerase I transcription	Any process that modulates the frequency, rate or extent of termination of RNA polymerase I transcription.	tmpzr1t_l9r_go_relaxed.owl	regulation of transcription termination from RNA polymerase I promoter|regulation of transcription termination from Pol I promoter|regulation of RNA polymerase I transcription termination							dph	2011-06-10T08:43:39Z					biological_process											owl:Class	
GO:0009952	biolink:NamedThing	anterior/posterior pattern specification	The regionalization process in which specific areas of cell differentiation are determined along the anterior-posterior axis. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism.	tmpzr1t_l9r_go_relaxed.owl	anterior/posterior pattern formation													biological_process											owl:Class	
GO:0003002	biolink:NamedThing	regionalization	The pattern specification process that results in the subdivision of an axis or axes in space to define an area or volume in which specific patterns of cell differentiation will take place or in which cells interpret a specific environment.	tmpzr1t_l9r_go_relaxed.owl	pattern formation													biological_process											owl:Class	
GO:1903804	biolink:NamedThing	glycine import across plasma membrane	The directed movement of glycine from outside of a cell, across the plasma membrane and into the cytosol.	tmpzr1t_l9r_go_relaxed.owl	glycine import|glycine import into cell							bf	2012-05-11T01:16:45Z			GO:0036233		biological_process											owl:Class	
GO:0098656	biolink:NamedThing	anion transmembrane transport	The process in which an anion is transported across a membrane.	tmpzr1t_l9r_go_relaxed.owl	ATP hydrolysis coupled anion transmembrane transport											GO:0099133		biological_process											owl:Class	
GO:0042047	biolink:NamedThing	W-molybdopterin cofactor biosynthetic process	The chemical reactions and pathways resulting in the formation of the W-molybdopterin cofactor, essential for the catalytic activity of some enzymes. The cofactor consists of a mononuclear tungsten ion (W) coordinated by one or two molybdopterin ligands.	tmpzr1t_l9r_go_relaxed.owl	Moco biosynthesis|Moco biosynthetic process|W-molybdopterin cofactor formation|W-molybdopterin cofactor anabolism|W-molybdopterin cofactor synthesis|W-molybdopterin cofactor biosynthesis													biological_process											owl:Class	
GO:0008460	biolink:NamedThing	dTDP-glucose 4,6-dehydratase activity	Catalysis of the reaction: dTDP-glucose = dTDP-4-dehydro-6-deoxy-alpha-D-glucose + H(2)O.	tmpzr1t_l9r_go_relaxed.owl	dTDP-glucose 4,6-hydro-lyase activity|thymidine diphosphoglucose oxidoreductase activity|dTDPglucose 4,6-dehydratase activity|dTDPglucose 4,6-hydro-lyase activity|dTDP-glucose 4,6-hydro-lyase (dTDP-4-dehydro-6-deoxy-D-glucose-forming)|TDP-glucose oxidoreductase activity				MetaCyc:DTDPGLUCDEHYDRAT-RXN|KEGG_REACTION:R06513|EC:4.2.1.46|RHEA:17221									molecular_function											owl:Class	
GO:0033672	biolink:NamedThing	positive regulation of NAD+ kinase activity	Any process that activates or increases the frequency, rate or extent of NAD kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to an NAD molecule.	tmpzr1t_l9r_go_relaxed.owl	NAD+ kinase activator|up-regulation of NAD+ kinase activity|upregulation of NAD+ kinase activity|stimulation of NAD+ kinase activity|up regulation of NAD+ kinase activity													biological_process											owl:Class	
GO:0021503	biolink:NamedThing	neural fold bending	The morphogenesis of the neural fold elevations that results in the movement of the tips of the elevations towards each other in order to fuse.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0070167	biolink:NamedThing	regulation of biomineral tissue development	Any process that modulates the frequency, rate or extent of biomineral tissue development, the formation of hard tissues that consist mainly of inorganic compounds.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:2000026	biolink:NamedThing	regulation of multicellular organismal development	Any process that modulates the frequency, rate or extent of multicellular organismal development.	tmpzr1t_l9r_go_relaxed.owl								tb	2010-08-05T11:25:59Z					biological_process											owl:Class	
GO:1902107	biolink:NamedThing	positive regulation of leukocyte differentiation	Any process that activates or increases the frequency, rate or extent of leukocyte differentiation.	tmpzr1t_l9r_go_relaxed.owl	upregulation of leukocyte differentiation|activation of immune cell differentiation|up regulation of leukocyte differentiation|positive regulation of immune cell differentiation|activation of leucocyte differentiation|positive regulation of leucocyte differentiation|upregulation of leucocyte differentiation|up-regulation of leucocyte differentiation|upregulation of immune cell differentiation|up regulation of immune cell differentiation|activation of leukocyte differentiation|up-regulation of immune cell differentiation|up regulation of leucocyte differentiation|up-regulation of leukocyte differentiation							pr	2013-05-02T17:32:52Z					biological_process											owl:Class	
GO:1902105	biolink:NamedThing	regulation of leukocyte differentiation	Any process that modulates the frequency, rate or extent of leukocyte differentiation.	tmpzr1t_l9r_go_relaxed.owl	regulation of leucocyte differentiation|regulation of immune cell differentiation							pr	2013-05-02T17:32:42Z					biological_process											owl:Class	
GO:0034651	biolink:NamedThing	cortisol biosynthetic process	The chemical reactions and pathways resulting in the formation of cortisol, the steroid hormone 11-beta-17,21-trihydroxypregn-4-ene-3,20-dione. Cortisol is synthesized from cholesterol in the adrenal gland and controls carbohydrate, fat and protein metabolism and has anti-inflammatory properties.	tmpzr1t_l9r_go_relaxed.owl	cortisol anabolism|cortisol formation|cortisol biosynthesis|cortisol synthesis													biological_process											owl:Class	
GO:1902645	biolink:NamedThing	tertiary alcohol biosynthetic process	The chemical reactions and pathways resulting in the formation of tertiary alcohol.	tmpzr1t_l9r_go_relaxed.owl	tertiary alcohol biosynthesis|tertiary alcohol formation|tertiary alcohol synthesis|tertiary alcohol anabolism							tt	2014-01-21T17:54:02Z					biological_process											owl:Class	
GO:0032413	biolink:NamedThing	negative regulation of ion transmembrane transporter activity	Any process that stops or reduces the activity of an ion transporter.	tmpzr1t_l9r_go_relaxed.owl	inhibition of ion transporter activity|down regulation of ion transporter activity|down-regulation of ion transporter activity|downregulation of ion transporter activity|negative regulation of ion transporter activity													biological_process											owl:Class	
GO:0034766	biolink:NamedThing	negative regulation of ion transmembrane transport	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of ions from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	down regulation of transmembrane ion transport|downregulation of transmembrane ion transport|negative regulation of ion membrane transport|down-regulation of transmembrane ion transport|inhibition of transmembrane ion transport|negative regulation of transmembrane ion transport													biological_process											owl:Class	
GO:0097697	biolink:NamedThing	tRNA 5-carboxymethoxyuridine methyltransferase activity	Catalysis of the transfer of a methyl group from S-adenosylmethionine to a 5-carboxymethoxy-modified uridine residue in a tRNA molecule.	tmpzr1t_l9r_go_relaxed.owl								pr	2016-01-07T10:36:46Z					molecular_function											owl:Class	
GO:0016300	biolink:NamedThing	tRNA (uracil) methyltransferase activity	Catalysis of the transfer of a methyl group from a donor to a uracil residue in a tRNA molecule.	tmpzr1t_l9r_go_relaxed.owl	tRNA (uridine) methyltransferase activity					Note that the methyl donor is usually S-adenosyl-L-methionine, but there is at least one exception (see GO:0030698).						GO:0016431		molecular_function											owl:Class	
GO:2000302	biolink:NamedThing	positive regulation of synaptic vesicle exocytosis	Any process that activates or increases the frequency, rate or extent of synaptic vesicle exocytosis.	tmpzr1t_l9r_go_relaxed.owl								dph	2011-01-03T08:21:14Z					biological_process											owl:Class	
GO:0001956	biolink:NamedThing	positive regulation of neurotransmitter secretion	Any process that activates or increases the frequency, rate or extent of the regulated release of a neurotransmitter.	tmpzr1t_l9r_go_relaxed.owl	stimulation of neurotransmitter secretion|activation of neurotransmitter secretion|up regulation of neurotransmitter secretion|up-regulation of neurotransmitter secretion|upregulation of neurotransmitter secretion													biological_process											owl:Class	
GO:0071587	biolink:NamedThing	CAAX-box protein modification	The covalent alteration of one or more amino acid residues within the CAAX box region of CAAX box proteins.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-01-28T04:48:56Z					biological_process											owl:Class	
GO:0043687	biolink:NamedThing	post-translational protein modification	The process of covalently altering one or more amino acids in a protein after the protein has been completely translated and released from the ribosome.	tmpzr1t_l9r_go_relaxed.owl	posttranslational modification|post-translational modification|PTM|post-translational amino acid modification|posttranslational amino acid modification|posttranslational protein modification				Wikipedia:Posttranslational_modification	This term should only be used to annotate a protein modification process that occurs after the protein has been released from the ribosome, and is therefore strictly post-translational. Modification of a free protein (one not attached to a ribosome) and modification of a C-terminal residue are post-translational processes. Some protein modifications occur while the protein is still in the ribosome but before translation has been completed; these modification processes are considered co-translational and should not be annotated using this term.								biological_process											owl:Class	
GO:0045572	biolink:NamedThing	positive regulation of imaginal disc growth	Any process that activates or increases the frequency, rate or extent of imaginal disc growth.	tmpzr1t_l9r_go_relaxed.owl	up regulation of imaginal disc growth|upregulation of imaginal disc growth|stimulation of imaginal disc growth|activation of imaginal disc growth|up-regulation of imaginal disc growth													biological_process											owl:Class	
GO:0045570	biolink:NamedThing	regulation of imaginal disc growth	Any process that modulates the frequency, rate or extent of the growth of the imaginal disc.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0015189	biolink:NamedThing	L-lysine transmembrane transporter activity	Enables the transfer of L-lysine from one side of a membrane to the other. L-lysine is 2,6-diaminohexanoic acid.	tmpzr1t_l9r_go_relaxed.owl	histidine/arginine/lysine/ornithine porter activity|lysine permease activity|L-lysine permease											GO:0005293		molecular_function											owl:Class	
GO:0008324	biolink:NamedThing	cation transmembrane transporter activity	Enables the transfer of cation from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	transmembrane cation transporter activity													molecular_function											owl:Class	
GO:0090063	biolink:NamedThing	positive regulation of microtubule nucleation	Any process that increases the rate, frequency or extent of microtubule nucleation. Microtubule nucleation is the 'de novo' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates, some of which go on to support formation of a complete microtubule. Microtubule nucleation usually occurs from a specific site within a cell.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-08-12T11:33:09Z					biological_process											owl:Class	
GO:0010968	biolink:NamedThing	regulation of microtubule nucleation	Any process that modulates the rate, frequency or extent of microtubule nucleation. Microtubule nucleation is the 'de novo' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates, some of which go on to support formation of a complete microtubule. Microtubule nucleation usually occurs from a specific site within a cell.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-05-20T11:51:21Z					biological_process											owl:Class	
GO:1905850	biolink:NamedThing	positive regulation of forward locomotion	Any process that activates or increases the frequency, rate or extent of forward locomotion.	tmpzr1t_l9r_go_relaxed.owl	activation of forward locomotion|upregulation of forward locomotion|up-regulation of forward locomotion|up regulation of forward locomotion							rz	2017-01-23T11:04:05Z					biological_process											owl:Class	
GO:0040017	biolink:NamedThing	positive regulation of locomotion	Any process that activates or increases the frequency, rate or extent of locomotion of a cell or organism.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of locomotion|activation of locomotion|upregulation of locomotion|up regulation of locomotion|stimulation of locomotion													biological_process											owl:Class	
GO:0090344	biolink:NamedThing	negative regulation of cell aging	Any process that decreases the rate, frequency, or extent of cell aging. Cell aging is the progression of the cell from its inception to the end of its lifespan.	tmpzr1t_l9r_go_relaxed.owl								tb	2010-06-02T10:12:37Z					biological_process											owl:Class	
GO:0090342	biolink:NamedThing	regulation of cell aging	Any process that modulates the rate, frequency, or extent of cell aging. Cell aging is the progression of the cell from its inception to the end of its lifespan.	tmpzr1t_l9r_go_relaxed.owl								tb	2010-06-02T10:12:37Z					biological_process											owl:Class	
GO:0030995	biolink:NamedThing	cell septum edging catabolic process	The chemical reactions and pathways resulting in the dissolution of the septum edging during cell separation.	tmpzr1t_l9r_go_relaxed.owl	cell septum edging hydrolysis|septum edging hydrolysis|hydrolysis of cell septum edging|hydrolysis of edging of cell septum													biological_process											owl:Class	
GO:0071999	biolink:NamedThing	extracellular polysaccharide catabolic process	The chemical reactions and pathways resulting in the breakdown of polysaccharides used in extracellular structures.	tmpzr1t_l9r_go_relaxed.owl	extracellular polysaccharide breakdown|extracellular polysaccharide catabolism|extracellular polysaccharide degradation							mah	2010-10-25T05:11:25Z					biological_process											owl:Class	
GO:1901631	biolink:NamedThing	positive regulation of presynaptic membrane organization	Any process that activates or increases the frequency, rate or extent of presynaptic membrane organization.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of presynaptic membrane organisation|up regulation of presynaptic membrane organisation|positive regulation of pre-synaptic membrane organization|upregulation of presynaptic membrane organisation|up-regulation of presynaptic membrane organization|upregulation of presynaptic membrane organization|up regulation of presynaptic membrane organization|activation of presynaptic membrane organisation|up-regulation of presynaptic membrane organisation|activation of presynaptic membrane organization							ans	2012-11-15T11:40:40Z					biological_process											owl:Class	
GO:2000766	biolink:NamedThing	negative regulation of cytoplasmic translation	Any process that stops, prevents or reduces the frequency, rate or extent of cytoplasmic translation.	tmpzr1t_l9r_go_relaxed.owl								vw	2011-06-20T10:39:23Z					biological_process											owl:Class	
GO:0016936	biolink:NamedThing	galactoside binding	Binding to a glycoside in which the sugar group is galactose.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0043847	biolink:NamedThing	DNA polymerase III, clamp loader chi/psi subcomplex	A dimer composed of the chi and psi subunits which is a subassembly of the DNA polymerase III clamp loader complex and serves as a bridge between the DnaX complex and the single-stranded DNA-binding protein (SSB).	tmpzr1t_l9r_go_relaxed.owl	DNA polymerase III, DnaX complex, chi/psi subcomplex													cellular_component											owl:Class	
GO:0050190	biolink:NamedThing	phosphoglucokinase activity	Catalysis of the reaction: alpha-D-glucose 1-phosphate + ATP = alpha-D-glucose 1,6-bisphosphate + ADP + 2 H(+).	tmpzr1t_l9r_go_relaxed.owl	ATP:D-glucose-1-phosphate 6-phosphotransferase activity|phosphoglucokinase (phosphorylating)|glucose-phosphate kinase activity|ATP:alpha-D-glucose-1-phosphate 6-phosphotransferase activity				RHEA:13377|MetaCyc:PHOSPHOGLUCOKINASE-RXN|EC:2.7.1.10|KEGG_REACTION:R00949									molecular_function											owl:Class	
GO:0090194	biolink:NamedThing	negative regulation of glomerulus development	Any process that decreases the rate, frequency or extent of glomerulus development, the progression of the glomerulus over time from its initial formation until its mature state. The glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-12-18T11:17:13Z					biological_process											owl:Class	
GO:0090192	biolink:NamedThing	regulation of glomerulus development	Any process that modulates the rate, frequency or extent of glomerulus development, the progression of the glomerulus over time from its initial formation until its mature state. The glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-12-18T11:17:13Z					biological_process											owl:Class	
GO:0008108	biolink:NamedThing	UDP-glucose:hexose-1-phosphate uridylyltransferase activity	Catalysis of the reaction: alpha-D-galactose 1-phosphate + UDP-D-glucose = alpha-D-glucose 1-phosphate + UDP-D-galactose.	tmpzr1t_l9r_go_relaxed.owl	UDP-glucose-hexose-1-phosphate uridylyltransferase activity|Gal-1-P uridylyltransferase activity|UDP-glucose:alpha-D-galactose-1-phosphate uridylyltransferase activity|uridyltransferase activity|UDPglucose:alpha-D-galactose-1-phosphate uridylyltransferase activity|uridylyl removing enzyme activity|UDPglucose-hexose-1-phosphate uridylyltransferase activity|galactose-1-phosphate uridylyltransferase activity|hexose 1-phosphate uridyltransferase activity|hexose-1-phosphate uridylyltransferase activity|uridyl transferase activity				Reactome:R-HSA-70361|MetaCyc:GALACTURIDYLYLTRANS-RXN|EC:2.7.7.12|KEGG_REACTION:R00955|RHEA:13989|Reactome:R-HSA-5610038									molecular_function											owl:Class	
GO:0070569	biolink:NamedThing	uridylyltransferase activity	Catalysis of the transfer of an uridylyl group to an acceptor.	tmpzr1t_l9r_go_relaxed.owl	uridyltransferase activity|uridyl transferase activity							mah	2009-04-15T11:06:07Z					molecular_function											owl:Class	
GO:0034116	biolink:NamedThing	positive regulation of heterotypic cell-cell adhesion	Any process that activates or increases the frequency, rate, or extent of heterotypic cell-cell adhesion.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0034114	biolink:NamedThing	regulation of heterotypic cell-cell adhesion	Any process that modulates the frequency, rate, or extent of heterotypic cell-cell adhesion.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0009441	biolink:NamedThing	glycolate metabolic process	The chemical reactions and pathways involving glycolate, the anion of hydroxyethanoic acid (glycolic acid).	tmpzr1t_l9r_go_relaxed.owl	glycolate metabolism				MetaCyc:GLYCOLATEMET-PWY									biological_process											owl:Class	
GO:0034308	biolink:NamedThing	primary alcohol metabolic process	The chemical reactions and pathways involving primary alcohols. A primary alcohol is any alcohol in which a hydroxy group, -OH, is attached to a saturated carbon atom which has either three hydrogen atoms attached to it or only one other carbon atom and two hydrogen atoms attached to it.	tmpzr1t_l9r_go_relaxed.owl	primary alcohol metabolism|monohydric alcohol metabolic process													biological_process											owl:Class	
GO:0031431	biolink:NamedThing	Dbf4-dependent protein kinase complex	A heterodimeric protein complex required for the activation of DNA replication origins; comprises a catalytic subunit and a regulatory subunit (in Saccharomyces, Cdc7p and Dbf4p, respectively); complexes identified in other species generally contain proteins related to the Saccharomyces proteins.	tmpzr1t_l9r_go_relaxed.owl	Cdc7-Dbf4 complex|Hsk1-Dfp1 kinase complex|DDK													cellular_component											owl:Class	
GO:0140535	biolink:NamedThing	intracellular protein-containing complex	A protein-containing complex located intracellularly.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/19952						pg	2020-10-28T14:40:16Z					cellular_component											owl:Class	
GO:0060876	biolink:NamedThing	semicircular canal formation	The developmental process pertaining to the initial formation of the semicircular canal from the otic vesicle. This process begins with the regionalization of the vesicle that specifies the area where the vesicles will form and continues through the process of fusion which forms the initial tubes.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-08-13T09:45:07Z					biological_process											owl:Class	
GO:0035148	biolink:NamedThing	tube formation	Creation of the central hole of a tube in an anatomical structure through which gases and/or liquids flow.	tmpzr1t_l9r_go_relaxed.owl	lumen formation in an anatomical structure|tube lumen formation													biological_process											owl:Class	
GO:0071222	biolink:NamedThing	cellular response to lipopolysaccharide	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipopolysaccharide stimulus; lipopolysaccharide is a major component of the cell wall of gram-negative bacteria.	tmpzr1t_l9r_go_relaxed.owl	cellular response to endotoxin|cellular response to LPS							mah	2009-12-03T01:29:29Z					biological_process											owl:Class	
GO:0050774	biolink:NamedThing	negative regulation of dendrite morphogenesis	Any process that stops, prevents, or reduces the frequency, rate or extent of dendrite morphogenesis.	tmpzr1t_l9r_go_relaxed.owl	inhibition of dendrite morphogenesis|downregulation of dendrite morphogenesis|down regulation of dendrite morphogenesis|down-regulation of dendrite morphogenesis													biological_process											owl:Class	
GO:0048814	biolink:NamedThing	regulation of dendrite morphogenesis	Any process that modulates the frequency, rate or extent of dendrite morphogenesis.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0032827	biolink:NamedThing	negative regulation of natural killer cell differentiation involved in immune response	Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer cell differentiation as part of an immune response.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of natural killer cell differentiation during immune response|negative regulation of NK cell differentiation during immune response|downregulation of natural killer cell differentiation during immune response|down-regulation of natural killer cell differentiation during immune response|inhibition of natural killer cell differentiation during immune response|down regulation of natural killer cell differentiation during immune response|negative regulation of natural killer cell development involved in immune response					Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.								biological_process											owl:Class	
GO:0032826	biolink:NamedThing	regulation of natural killer cell differentiation involved in immune response	Any process that modulates the frequency, rate or extent of natural killer cell differentiation as part of an immune response.	tmpzr1t_l9r_go_relaxed.owl	regulation of natural killer cell differentiation during immune response|regulation of natural killer cell development involved in immune response|regulation of NK cell differentiation during immune response					Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.								biological_process											owl:Class	
GO:0050203	biolink:NamedThing	oxalate-CoA ligase activity	Catalysis of the reaction: ATP + CoA + oxalate = AMP + diphosphate + H(+) + oxalyl-CoA.	tmpzr1t_l9r_go_relaxed.owl	oxalate:CoA ligase (AMP-forming)|oxalyl coenzyme A synthetase activity|oxalyl-CoA synthetase activity				MetaCyc:OXALATE--COA-LIGASE-RXN|EC:6.2.1.8|RHEA:18293|KEGG_REACTION:R01558									molecular_function											owl:Class	
GO:0016878	biolink:NamedThing	acid-thiol ligase activity	Catalysis of the joining of an acid and a thiol via a carbon-sulfur bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.	tmpzr1t_l9r_go_relaxed.owl					EC:6.2.1.-									molecular_function											owl:Class	
GO:0051573	biolink:NamedThing	negative regulation of histone H3-K9 methylation	Any process that stops, prevents, or reduces the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 9 of histone H3.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of histone H3-K9 methylation|downregulation of histone H3-K9 methylation|down regulation of histone H3-K9 methylation|inhibition of histone H3-K9 methylation													biological_process											owl:Class	
GO:1903296	biolink:NamedThing	positive regulation of glutamate secretion, neurotransmission	Any process that activates or increases the frequency, rate or extent of glutamate secretion, where glutamate acts as a neurotransmitter.	tmpzr1t_l9r_go_relaxed.owl	activation of glutamate secretion, neurotransmission|up-regulation of glutamate secretion, neurotransmission|up regulation of glutamate secretion, neurotransmission|upregulation of glutamate secretion, neurotransmission					An example of this is Rab3gap1 in mouse (Q80UJ7) in PMID:16782817 inferred from mutant phenotype		pad	2014-08-13T13:54:31Z					biological_process											owl:Class	
GO:1901435	biolink:NamedThing	negative regulation of toluene catabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of toluene catabolic process.	tmpzr1t_l9r_go_relaxed.owl	inhibition of toluene catabolism|negative regulation of toluene breakdown|inhibition of toluene breakdown|negative regulation of toluene degradation|downregulation of toluene breakdown|negative regulation of toluene catabolism|down-regulation of toluene catabolism|down regulation of toluene catabolism|inhibition of toluene degradation|downregulation of toluene degradation|down-regulation of toluene catabolic process|down-regulation of toluene breakdown|down-regulation of toluene degradation|downregulation of toluene catabolism|inhibition of toluene catabolic process|down regulation of toluene degradation|downregulation of toluene catabolic process|down regulation of toluene catabolic process|down regulation of toluene breakdown							tt	2012-10-01T21:13:41Z					biological_process											owl:Class	
GO:0003186	biolink:NamedThing	tricuspid valve morphogenesis	The process in which the structure of the tricuspid valve is generated and organized.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-10-08T12:05:45Z					biological_process											owl:Class	
GO:0003181	biolink:NamedThing	atrioventricular valve morphogenesis	The process in which the structure of the atrioventricular valve is generated and organized.	tmpzr1t_l9r_go_relaxed.owl	AV valve morphogenesis							dph	2009-10-08T11:31:59Z					biological_process											owl:Class	
GO:0060893	biolink:NamedThing	limb granular cell fate specification	The process in which a cell becomes capable of differentiating autonomously into an limb granular cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-08-13T01:44:14Z					biological_process											owl:Class	
GO:0060573	biolink:NamedThing	cell fate specification involved in pattern specification	The process involved in the specification of the identity of a cell in a field of cells that is being instructed as to how to differentiate. Once specification has taken place, that cell will be committed to differentiate down a specific pathway if left in its normal environment.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-05-05T02:19:14Z					biological_process											owl:Class	
GO:0004947	biolink:NamedThing	bradykinin receptor activity	Combining with bradykinin to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:2001145	biolink:NamedThing	negative regulation of phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity	Any process that stops, prevents or reduces the frequency, rate or extent of phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity.	tmpzr1t_l9r_go_relaxed.owl								yaf	2011-10-19T10:41:28Z					biological_process											owl:Class	
GO:2001144	biolink:NamedThing	regulation of phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity	Any process that modulates the frequency, rate or extent of phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity.	tmpzr1t_l9r_go_relaxed.owl								yaf	2011-10-19T10:41:25Z					biological_process											owl:Class	
GO:2001256	biolink:NamedThing	regulation of store-operated calcium entry	Any process that modulates the frequency, rate or extent of store-operated calcium entry.	tmpzr1t_l9r_go_relaxed.owl	regulation of SOCE|regulation of store-operated calcium import|regulation of capacitative calcium entry|regulation of calcium ion import							vk	2011-12-07T07:08:38Z					biological_process											owl:Class	
GO:0051924	biolink:NamedThing	regulation of calcium ion transport	Any process that modulates the frequency, rate or extent of the directed movement of calcium ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	regulation of calcium transport													biological_process											owl:Class	
GO:0015438	biolink:NamedThing	ABC-type teichoic acid transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + teichoic acid(in) = ADP + phosphate + teichoic acid(out).	tmpzr1t_l9r_go_relaxed.owl	ATP-dependent teichoic acid transmembrane transporter activity|teichoic acid transmembrane transporter activity|ABC-type teichoic-acid transporter|ATPase-coupled teichoic acid transmembrane transporter activity|teichoic-acid-transporting ATPase activity|teichoic-acid ABC transporter				MetaCyc:3.6.3.40-RXN|EC:7.5.2.4							GO:0015162		molecular_function											owl:Class	
GO:0022884	biolink:NamedThing	macromolecule transmembrane transporter activity	Enables the transfer of a macromolecule from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1900490	biolink:NamedThing	positive regulation of hydroxymethylglutaryl-CoA reductase (NADPH) activity	Any process that activates or increases the frequency, rate or extent of hydroxymethylglutaryl-CoA reductase (NADPH) activity.	tmpzr1t_l9r_go_relaxed.owl	upregulation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase activity|up regulation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase activity|up-regulation of HMG-CoA reductase activity|up regulation of HMG-CoA reductase activity|upregulation of hydroxymethylglutaryl-CoA reductase (NADPH) activity|up regulation of hydroxymethylglutaryl-CoA reductase (NADPH) activity|positive regulation of HMG-CoA reductase activity|up-regulation of hydroxymethylglutaryl-CoA reductase (NADPH) activity|activation of hydroxymethylglutaryl-CoA reductase (NADPH) activity|up-regulation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase activity|upregulation of HMG-CoA reductase activity|positive regulation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase activity|activation of HMG-CoA reductase activity|activation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase activity							al	2012-05-02T03:01:43Z					biological_process											owl:Class	
GO:0051353	biolink:NamedThing	positive regulation of oxidoreductase activity	Any process that activates or increases the frequency, rate or extent of oxidoreductase activity, the catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered.	tmpzr1t_l9r_go_relaxed.owl	up regulation of oxidoreductase activity|activation of oxidoreductase activity|stimulation of oxidoreductase activity|oxidoreductase activator|up-regulation of oxidoreductase activity|upregulation of oxidoreductase activity|ribonucleotide reductase activating enzyme activity											GO:0009391		biological_process											owl:Class	
GO:1902953	biolink:NamedThing	positive regulation of ER to Golgi vesicle-mediated transport	Any process that activates or increases the frequency, rate or extent of ER to Golgi vesicle-mediated transport.	tmpzr1t_l9r_go_relaxed.owl	up regulation of ER to Golgi vesicle-mediated transport|upregulation of rough endoplasmic reticulum to cis-Golgi vesicle-mediated transport|positive regulation of rough endoplasmic reticulum to cis-Golgi transport|upregulation of rough endoplasmic reticulum to cis-Golgi transport|positive regulation of rough endoplasmic reticulum to cis-Golgi vesicle-mediated transport|up regulation of endoplasmic reticulum to Golgi transport|up regulation of rough endoplasmic reticulum to cis-Golgi vesicle-mediated transport|up-regulation of rough endoplasmic reticulum to cis-Golgi transport|activation of rough endoplasmic reticulum to cis-Golgi vesicle-mediated transport|activation of rough ER to cis-Golgi vesicle-mediated transport|up-regulation of ER to Golgi vesicle-mediated transport|up-regulation of rough ER to cis-Golgi transport|up regulation of rough ER to cis-Golgi vesicle-mediated transport|positive regulation of rough ER to cis-Golgi transport|activation of rough endoplasmic reticulum to cis-Golgi transport|upregulation of ER to Golgi vesicle-mediated transport|up regulation of rough endoplasmic reticulum to cis-Golgi transport|up regulation of endoplasmic reticulum to Golgi vesicle-mediated transport|upregulation of endoplasmic reticulum to Golgi transport|positive regulation of rough ER to cis-Golgi vesicle-mediated transport|positive regulation of endoplasmic reticulum to Golgi transport|upregulation of rough ER to cis-Golgi vesicle-mediated transport|upregulation of rough ER to cis-Golgi transport|positive regulation of ER to Golgi transport|up regulation of ER to Golgi transport|upregulation of ER to Golgi transport|upregulation of endoplasmic reticulum to Golgi vesicle-mediated transport|up-regulation of endoplasmic reticulum to Golgi transport|up-regulation of ER to Golgi transport|up-regulation of endoplasmic reticulum to Golgi vesicle-mediated transport|activation of rough ER to cis-Golgi transport|activation of endoplasmic reticulum to Golgi transport|up-regulation of rough ER to cis-Golgi vesicle-mediated transport|activation of ER to Golgi vesicle-mediated transport|activation of ER to Golgi transport|up-regulation of rough endoplasmic reticulum to cis-Golgi vesicle-mediated transport|up regulation of rough ER to cis-Golgi transport|positive regulation of endoplasmic reticulum to Golgi vesicle-mediated transport|activation of endoplasmic reticulum to Golgi vesicle-mediated transport							sjp	2014-05-02T08:59:18Z					biological_process											owl:Class	
GO:0032388	biolink:NamedThing	positive regulation of intracellular transport	Any process that activates or increases the frequency, rate or extent of the directed movement of substances within cells.	tmpzr1t_l9r_go_relaxed.owl	up regulation of intracellular transport|up-regulation of intracellular transport|upregulation of intracellular transport|activation of intracellular transport|stimulation of intracellular transport													biological_process											owl:Class	
GO:0031452	biolink:NamedThing	negative regulation of heterochromatin assembly	Any process that stops, prevents, or reduces the frequency, rate or extent of heterochromatin formation.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of heterochromatin formation|inhibition of heterochromatin formation|downregulation of heterochromatin formation|down regulation of heterochromatin formation|down-regulation of heterochromatin formation													biological_process											owl:Class	
GO:0120262	biolink:NamedThing	negative regulation of heterochromatin organization	Any process that stops, prevents, or reduces the frequency, rate or extent of heterochromatin organization.	tmpzr1t_l9r_go_relaxed.owl	downregulation of heterochromatin organization|inhibition of heterochromatin organization|down regulation of heterochromatin organization|down-regulation of heterochromatin organization	https://github.com/geneontology/go-ontology/issues/20020						krc	2020-09-29T20:12:30Z					biological_process											owl:Class	
GO:0031409	biolink:NamedThing	pigment binding	Binding to a pigment, a general or particular coloring matter in living organisms, e.g. melanin.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0005488	biolink:NamedThing	binding	The selective, non-covalent, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule.	tmpzr1t_l9r_go_relaxed.owl	ligand				Wikipedia:Binding_(molecular)	Note that this term is in the subset of terms that should not be used for direct, manual gene product annotation. Please choose a more specific child term, or request a new one if no suitable term is available. For ligands that bind to signal transducing receptors, consider the molecular function term 'receptor binding ; GO:0005102' and its children.								molecular_function											owl:Class	
GO:0031396	biolink:NamedThing	regulation of protein ubiquitination	Any process that modulates the frequency, rate or extent of the addition of ubiquitin groups to a protein.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0045823	biolink:NamedThing	positive regulation of heart contraction	Any process that activates or increases the frequency, rate or extent of heart contraction.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of heart contraction|activation of heart contraction|positive regulation of cardiac contraction|stimulation of heart contraction|up regulation of heart contraction|upregulation of heart contraction													biological_process											owl:Class	
GO:1903524	biolink:NamedThing	positive regulation of blood circulation	Any process that activates or increases the frequency, rate or extent of blood circulation.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of hemolymph circulation|upregulation of hemolymph circulation|activation of blood circulation|up-regulation of hemolymph circulation|upregulation of blood circulation|up regulation of hemolymph circulation|activation of hemolymph circulation|up regulation of blood circulation|up-regulation of blood circulation							mr	2014-10-06T18:39:13Z					biological_process											owl:Class	
GO:0033631	biolink:NamedThing	cell-cell adhesion mediated by integrin	The attachment of one cell to another cell via an integrin, a heterodimeric adhesion receptor formed by the non-covalent association of particular alpha and beta subunits.	tmpzr1t_l9r_go_relaxed.owl	cell-cell adhesion mediated by integrin complex													biological_process											owl:Class	
GO:0033627	biolink:NamedThing	cell adhesion mediated by integrin	The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via an integrin, a heterodimeric adhesion receptor formed by the non-covalent association of particular alpha and beta subunits.	tmpzr1t_l9r_go_relaxed.owl	cell adhesion mediated by integrin complex													biological_process											owl:Class	
GO:0090441	biolink:NamedThing	trehalose biosynthesis in response to heat stress	The chemical reactions and pathways resulting in the formation of trehalose that occur as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.	tmpzr1t_l9r_go_relaxed.owl	trehalose biosynthetic process in response to heat stress							tb	2012-08-23T13:53:07Z					biological_process											owl:Class	
GO:0070414	biolink:NamedThing	trehalose metabolism in response to heat stress	The chemical reactions and pathways involving trehalose that occur as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.	tmpzr1t_l9r_go_relaxed.owl	trehalose metabolic process involved in response to heat stress													biological_process											owl:Class	
GO:0080173	biolink:NamedThing	male-female gamete recognition during double fertilization forming a zygote and endosperm	The initial contact step made between the male gamete and the female gamete during double fertilization forming a zygote and endosperm. An example can be found in Arabidopsis thaliana.	tmpzr1t_l9r_go_relaxed.owl	male-female gamete recognition|gamete recognition							dhl	2011-04-26T04:58:58Z					biological_process											owl:Class	
GO:0009988	biolink:NamedThing	cell-cell recognition	Cell recognition between cells. May involve the formation of specialized cell junctions.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0019617	biolink:NamedThing	protocatechuate catabolic process, meta-cleavage	The chemical reactions and pathways resulting in the breakdown of protocatechuate, the anion of 3,4-dihydroxybenzoic acid, to yield oxaloacetate and pyruvate.	tmpzr1t_l9r_go_relaxed.owl	protocatechuate degradation, meta-cleavage|protocatechuate catabolic process to oxaloacetate and pyruvate|protocatechuate breakdown, meta-cleavage|3,4-dihydroxybenzoate catabolic process, meta-cleavage				MetaCyc:P184-PWY									biological_process											owl:Class	
GO:0006107	biolink:NamedThing	oxaloacetate metabolic process	The chemical reactions and pathways involving oxaloacetate, the anion of oxobutanedioic acid, an important intermediate in metabolism, especially as a component of the TCA cycle.	tmpzr1t_l9r_go_relaxed.owl	oxaloacetate metabolism													biological_process											owl:Class	
GO:0070457	biolink:NamedThing	D-galactose-1-phosphate phosphatase activity	Catalysis of the reaction: D-galactose-1-phosphate + H2O = D-galactose + phosphate.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0070456	biolink:NamedThing	galactose-1-phosphate phosphatase activity	Catalysis of the reaction: galactose-1-phosphate + H2O = galactose + phosphate.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0004945	biolink:NamedThing	angiotensin type II receptor activity	An angiotensin receptor activity that acts via Gi protein coupling and cGMP (NO) generation, and may also act via additional signaling mechanisms.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0001595	biolink:NamedThing	angiotensin receptor activity	Combining with angiotensin to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0050795	biolink:NamedThing	regulation of behavior	Any process that modulates the frequency, rate or extent of behavior, the internally coordinated responses (actions or inactions) of whole living organisms (individuals or groups) to internal or external stimuli.	tmpzr1t_l9r_go_relaxed.owl	regulation of behaviour													biological_process											owl:Class	
GO:0050967	biolink:NamedThing	detection of electrical stimulus involved in sensory perception of pain	The series of events that contribute to the perception of pain in which an electrical stimulus is received and converted into a molecular signal.	tmpzr1t_l9r_go_relaxed.owl	perception of pain, detection of electrical stimulus|perception of pain, sensory transduction of electrical stimulus|perception of pain, sensory detection of electrical stimulus|detection of electrical stimulus during sensory perception of pain|sensory detection of electrical stimulus during perception of pain|sensory transduction of electrical stimulus during perception of pain													biological_process											owl:Class	
GO:0050981	biolink:NamedThing	detection of electrical stimulus	The series of events by which an electrical stimulus is received and converted into a molecular signal.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0060770	biolink:NamedThing	negative regulation of epithelial cell proliferation involved in prostate gland development	Any process that decreases the rate, frequency or extent of epithelial cell proliferation that contributes to the progression of the prostate gland over time.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-07-08T07:40:27Z					biological_process											owl:Class	
GO:0050680	biolink:NamedThing	negative regulation of epithelial cell proliferation	Any process that stops, prevents or reduces the rate or extent of epithelial cell proliferation.	tmpzr1t_l9r_go_relaxed.owl	downregulation of epithelial cell proliferation|down regulation of epithelial cell proliferation|down-regulation of epithelial cell proliferation|inhibition of epithelial cell proliferation													biological_process											owl:Class	
GO:0103023	biolink:NamedThing	ITPase activity	Catalysis of the reaction: ITP + H2O <=> H+ + IDP + hydrogenphosphate.	tmpzr1t_l9r_go_relaxed.owl					RHEA:28330|EC:3.6.1.73|MetaCyc:RXN0-5073									molecular_function											owl:Class	
GO:0016818	biolink:NamedThing	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	Catalysis of the hydrolysis of any acid anhydride which contains phosphorus.	tmpzr1t_l9r_go_relaxed.owl					EC:3.6.1.-									molecular_function											owl:Class	
GO:2000562	biolink:NamedThing	negative regulation of CD4-positive, alpha-beta T cell proliferation	Any process that stops, prevents or reduces the frequency, rate or extent of CD4-positive, alpha-beta T cell proliferation.	tmpzr1t_l9r_go_relaxed.owl								ebc	2011-04-03T09:01:11Z					biological_process											owl:Class	
GO:2000515	biolink:NamedThing	negative regulation of CD4-positive, alpha-beta T cell activation	Any process that stops, prevents or reduces the frequency, rate or extent of CD4-positive, alpha-beta T cell activation.	tmpzr1t_l9r_go_relaxed.owl								ebc	2011-03-22T10:37:02Z					biological_process											owl:Class	
GO:0006110	biolink:NamedThing	regulation of glycolytic process	Any process that modulates the frequency, rate or extent of glycolysis.	tmpzr1t_l9r_go_relaxed.owl	regulation of glycolysis involved in cellular glucose homeostasis											GO:0090525		biological_process											owl:Class	
GO:0042325	biolink:NamedThing	regulation of phosphorylation	Any process that modulates the frequency, rate or extent of addition of phosphate groups into a molecule.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0032069	biolink:NamedThing	regulation of nuclease activity	Any process that modulates the frequency, rate or extent of nuclease activity, the hydrolysis of ester linkages within nucleic acids.	tmpzr1t_l9r_go_relaxed.owl	nuclease regulator activity													biological_process											owl:Class	
GO:0071785	biolink:NamedThing	endoplasmic reticulum cisternal network maintenance	The organization process that preserves the endoplasmic reticulum (ER) cisternal network in a stable functional or structural state. The ER cisternal network is the ER part that comprises the membranes with low curvature in cross-section.	tmpzr1t_l9r_go_relaxed.owl	ER cisternal network maintenance							mah	2010-09-01T01:52:26Z					biological_process											owl:Class	
GO:0090177	biolink:NamedThing	establishment of planar polarity involved in neural tube closure	Coordinated organization of groups of cells in the plane of an epithelium that contributes to the closure of the neural tube.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-12-14T10:38:46Z					biological_process											owl:Class	
GO:0001736	biolink:NamedThing	establishment of planar polarity	Coordinated organization of groups of cells in the plane of an epithelium, such that they all orient to similar coordinates.	tmpzr1t_l9r_go_relaxed.owl	establishment of planar cell polarity													biological_process											owl:Class	
GO:0039537	biolink:NamedThing	suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of the series of molecular signals generated as a consequence of a virus or viral RNA binding to a pattern recognition receptor (PRR) located in the cytoplasm. This is a mechanism by which the virus evades the host innate immune response.	tmpzr1t_l9r_go_relaxed.owl	suppression by virus of host RIG-I/MDA5 signaling pathway|suppression by virus of host RIG-I-like receptor (RLR) signaling pathway|suppression by virus of host cytoplasmic pattern recognition receptor signaling pathway in response to virus|suppression by virus of host RIG-like helicase signaling pathway|suppression by virus of host RIG-like receptor signaling pathway|suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signalling pathway|suppression by virus of host RLR signaling pathway							bf	2012-01-03T11:47:05Z					biological_process											owl:Class	
GO:0039503	biolink:NamedThing	suppression by virus of host innate immune response	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of the innate immune response of the host organism, the host's first line of defense.	tmpzr1t_l9r_go_relaxed.owl	inhibition of host innate immune response by virus|negative regulation by virus of host innate immune response|suppression by virus of host innate immunity|negative regulation by virus of host innate immunity							bf	2011-05-11T04:31:17Z					biological_process											owl:Class	
GO:0001972	biolink:NamedThing	retinoic acid binding	Binding to retinoic acid, 3,7-dimethyl-9-(2,6,-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic acid.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0035462	biolink:NamedThing	determination of left/right asymmetry in diencephalon	The establishment of the diencephalon with respect to the left and right halves.	tmpzr1t_l9r_go_relaxed.owl								bf	2010-04-19T11:50:11Z					biological_process											owl:Class	
GO:0035545	biolink:NamedThing	determination of left/right asymmetry in nervous system	The establishment of the nervous system with respect to the left and right halves.	tmpzr1t_l9r_go_relaxed.owl								bf	2010-05-11T01:53:33Z					biological_process											owl:Class	
GO:0033455	biolink:NamedThing	GCA codon-amino acid adaptor activity	A triplet codon-amino acid adaptor activity that recognizes a GCA codon.	tmpzr1t_l9r_go_relaxed.owl	alanine tRNA					Note that in the standard genetic code, GCA codes for alanine.								molecular_function											owl:Class	
GO:0030533	biolink:NamedThing	triplet codon-amino acid adaptor activity	The codon binding activity of a tRNA that positions an activated amino acid, mediating its insertion at the correct point in the sequence of a nascent polypeptide chain during protein synthesis.	tmpzr1t_l9r_go_relaxed.owl	transfer RNA|tRNA					Note that this term can be used in place of the obsolete term 'transfer RNA ; GO:0005563'.								molecular_function											owl:Class	
GO:0034921	biolink:NamedThing	cis-4,5-dihydroxy-4,5-dihydropyrene dehydrogenase activity	Catalysis of the reaction: cis-4,5-dihydroxy-4,5-dihydropyrene = 4,5-dihydroxypyrene + 2 H+ + 2 e-.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0935									molecular_function											owl:Class	
GO:0050569	biolink:NamedThing	glycolaldehyde dehydrogenase activity	Catalysis of the reaction: glycolaldehyde + H(2)O + NAD(+) = glycolate + 2 H(+) + NADH.	tmpzr1t_l9r_go_relaxed.owl	glycol aldehyde dehydrogenase activity|glycolaldehyde:NAD+ oxidoreductase activity				RHEA:20001|EC:1.2.1.21|MetaCyc:GLYCOLALD-DEHYDROG-RXN|KEGG_REACTION:R01333									molecular_function											owl:Class	
GO:0004029	biolink:NamedThing	aldehyde dehydrogenase (NAD+) activity	Catalysis of the reaction: an aldehyde + NAD+ + H2O = an acid + NADH + H+.	tmpzr1t_l9r_go_relaxed.owl	aldehyde dehydrogenase (NAD+)|NAD-dependent aldehyde dehydrogenase activity|NAD-dependent 4-hydroxynonenal dehydrogenase activity|m-methylbenzaldehyde dehydrogenase activity|aldehyde:NAD+ oxidoreductase activity|propionaldehyde dehydrogenase activity|CoA-independent aldehyde dehydrogenase activity|NAD-aldehyde dehydrogenase activity|NAD-linked aldehyde dehydrogenase activity				Reactome:R-HSA-6808487|EC:1.2.1.3|UM-BBD_enzymeID:e0024|Reactome:R-HSA-6808496|RHEA:16185|Reactome:R-HSA-71691|Reactome:R-HSA-5692261|Reactome:R-HSA-380608|MetaCyc:ALDHDEHYDROG-RXN|Reactome:R-HSA-5696091|Wikipedia:Aldehyde_dehydrogenase_(NAD+)|Reactome:R-HSA-389609|Reactome:R-HSA-71723|Reactome:R-HSA-6813749									molecular_function											owl:Class	
GO:1905150	biolink:NamedThing	regulation of voltage-gated sodium channel activity	Any process that modulates the frequency, rate or extent of voltage-gated sodium channel activity.	tmpzr1t_l9r_go_relaxed.owl	regulation of voltage gated sodium channel activity|regulation of voltage-sensitive sodium channel|regulation of voltage-gated sodium ion channel activity|regulation of voltage-dependent sodium channel activity							sl	2016-04-15T21:47:40Z					biological_process											owl:Class	
GO:0001546	biolink:NamedThing	preantral ovarian follicle growth	Increase in size of follicles surrounded by two or more layers of granulosa cells up to the onset of antrum formation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0022602	biolink:NamedThing	ovulation cycle process	A process involved in the sexual cycle seen in females, often with physiologic changes in the endometrium that recur at regular intervals during the reproductive years.	tmpzr1t_l9r_go_relaxed.owl	estrous cycle process|menstrual cycle process													biological_process											owl:Class	
GO:0048791	biolink:NamedThing	calcium ion-regulated exocytosis of neurotransmitter	The release of a neurotransmitter into the synaptic cleft by exocytosis of synaptic vesicles, where the release step is dependent on a rise in cytosolic calcium ion levels.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0017156	biolink:NamedThing	calcium-ion regulated exocytosis	The release of intracellular molecules (e.g. hormones, matrix proteins) contained within a membrane-bounded vesicle by fusion of the vesicle with the plasma membrane of a cell, induced by a rise in cytosolic calcium-ion levels.	tmpzr1t_l9r_go_relaxed.owl	calcium ion-dependent exocytosis					Note that the calcium regulated exocytosis pathway can be leaky: some level of exocytosis via this pathway occurs spontaneously.  This phenomenon underlies spontaneous neurotransmitter release from presynapses.  This phenomenon is distinct from the unregulated, calcium independent exocytosis pathway.								biological_process											owl:Class	
GO:0008289	biolink:NamedThing	lipid binding	Binding to a lipid.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0047989	biolink:NamedThing	hydroxybutyrate-dimer hydrolase activity	Catalysis of the reaction: (R)-3-[(R)-3-hydroxybutanoyloxy]butanoate + H(2)O = 2 (R)-3-hydroxybutanoate + H(+).	tmpzr1t_l9r_go_relaxed.owl	D-(-)-3-hydroxybutyrate-dimer hydrolase activity|(R)-3-((R)-3-hydroxybutanoyloxy)butanoate hydroxybutanoylhydrolase activity				MetaCyc:HYDROXYBUTYRATE-DIMER-HYDROLASE-RXN|KEGG_REACTION:R00048|RHEA:10172|EC:3.1.1.22									molecular_function											owl:Class	
GO:0070875	biolink:NamedThing	positive regulation of glycogen metabolic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving glycogen.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of glycogen metabolism							mah	2009-08-20T02:53:55Z					biological_process											owl:Class	
GO:0010907	biolink:NamedThing	positive regulation of glucose metabolic process	Any process that increases the rate, frequency or extent of glucose metabolism. Glucose metabolic processes are the chemical reactions and pathways involving glucose, the aldohexose gluco-hexose.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of glucose metabolism													biological_process											owl:Class	
GO:1901831	biolink:NamedThing	all-trans-neoxanthin metabolic process	The chemical reactions and pathways involving all-trans-neoxanthin.	tmpzr1t_l9r_go_relaxed.owl	neoxanthin metabolism|neoxanthin metabolic process|all-trans-neoxanthin metabolism							yaf	2013-01-22T12:43:46Z					biological_process											owl:Class	
GO:0016122	biolink:NamedThing	xanthophyll metabolic process	The chemical reactions and pathways involving xanthophylls, oxygen-containing carotenoids.	tmpzr1t_l9r_go_relaxed.owl	xanthophyll metabolism													biological_process											owl:Class	
GO:0046124	biolink:NamedThing	purine deoxyribonucleoside catabolic process	The chemical reactions and pathways resulting in the breakdown of any one of a family of organic molecules consisting of a purine base covalently bonded to a sugar deoxyribose (a deoxyribonucleoside).	tmpzr1t_l9r_go_relaxed.owl	purine deoxyribonucleoside catabolism|purine deoxyribonucleoside breakdown|purine deoxyribonucleoside degradation													biological_process											owl:Class	
GO:0046122	biolink:NamedThing	purine deoxyribonucleoside metabolic process	The chemical reactions and pathways involving any one of a family of organic molecules consisting of a purine base covalently bonded to a sugar deoxyribose (a deoxyribonucleoside).	tmpzr1t_l9r_go_relaxed.owl	purine deoxyribonucleoside metabolism													biological_process											owl:Class	
GO:1900100	biolink:NamedThing	positive regulation of plasma cell differentiation	Any process that activates or increases the frequency, rate or extent of plasma cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	activation of plasma cell differentiation|up regulation of plasma cell development|upregulation of plasma cell development|up-regulation of plasma cell differentiation|activation of plasma cell development|positive regulation of plasma cell development|up regulation of plasma cell differentiation|up-regulation of plasma cell development|upregulation of plasma cell differentiation							bf	2012-02-15T10:46:08Z					biological_process											owl:Class	
GO:1900098	biolink:NamedThing	regulation of plasma cell differentiation	Any process that modulates the frequency, rate or extent of plasma cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	regulation of plasma cell development							bf	2012-02-15T10:46:00Z					biological_process											owl:Class	
GO:0019297	biolink:NamedThing	coenzyme B metabolic process	The chemical reactions and pathways involving coenzyme B (7-mercaptoheptanoylthreonine phosphate), a coenzyme involved in the utilization of methane by methanogenic prokaryotes.	tmpzr1t_l9r_go_relaxed.owl	coenzyme B metabolism													biological_process											owl:Class	
GO:2000448	biolink:NamedThing	positive regulation of macrophage migration inhibitory factor signaling pathway	Any process that activates or increases the frequency, rate or extent of macrophage migration inhibitory factor signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of MIF signaling pathway|positive regulation of macrophage migration inhibitory factor signalling pathway							bf	2011-03-04T10:38:43Z					biological_process											owl:Class	
GO:2000446	biolink:NamedThing	regulation of macrophage migration inhibitory factor signaling pathway	Any process that modulates the frequency, rate or extent of macrophage migration inhibitory factor signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	regulation of MIF signaling pathway|regulation of macrophage migration inhibitory factor signalling pathway							bf	2011-03-04T10:37:39Z					biological_process											owl:Class	
GO:0061915	biolink:NamedThing	actin fusion focus localization	Any process in which an actin fusion focus are transported to, or maintained in, a specific location. The actin fusion focus is an aster-like, F-actin-containing structure at the mating projection tip where the cell wall is degraded during conjugation with cellular fusion.	tmpzr1t_l9r_go_relaxed.owl	actin fusion focus localisation							dph	2017-07-10T18:11:47Z					biological_process											owl:Class	
GO:0051641	biolink:NamedThing	cellular localization	A cellular localization process whereby a substance or cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in, a specific location within a cell including the localization of substances or cellular entities to the cell membrane.	tmpzr1t_l9r_go_relaxed.owl	establishment and maintenance of cellular localization|single-organism cellular localization|intracellular localization|single organism cellular localization|localization within cell|establishment and maintenance of localization in cell or cell membrane|cellular localisation							jl	2013-12-18T14:04:32Z			GO:1902580		biological_process											owl:Class	
GO:0008427	biolink:NamedThing	calcium-dependent protein kinase inhibitor activity	Binds to and stops, prevents or reduces the activity of a calcium-dependent protein kinase.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0009965	biolink:NamedThing	leaf morphogenesis	The process in which the anatomical structures of the leaf are generated and organized.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1905392	biolink:NamedThing	plant organ morphogenesis	The developmental process by which a plant organ is generated and organized.	tmpzr1t_l9r_go_relaxed.owl								tb	2016-08-24T00:21:19Z					biological_process											owl:Class	
GO:0036062	biolink:NamedThing	presynaptic periactive zone	A region that surrounds the active zone of the presynaptic plasma membrane, and is specialized for the control of synaptic development.	tmpzr1t_l9r_go_relaxed.owl	pre-synaptic periactive zone|periactive zone							bf	2011-12-14T02:25:29Z					cellular_component											owl:Class	
GO:0097060	biolink:NamedThing	synaptic membrane	A specialized area of membrane on either the presynaptic or the postsynaptic side of a synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell.	tmpzr1t_l9r_go_relaxed.owl								pr	2011-06-07T11:22:09Z					cellular_component											owl:Class	
GO:0003348	biolink:NamedThing	cardiac endothelial cell differentiation	The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cardiac endothelial cell.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-12-01T11:12:05Z					biological_process											owl:Class	
GO:0035051	biolink:NamedThing	cardiocyte differentiation	The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cell that will form part of the cardiac organ of an individual.	tmpzr1t_l9r_go_relaxed.owl	cardiac cell differentiation|heart cell differentiation													biological_process											owl:Class	
GO:0036174	biolink:NamedThing	butane monooxygenase activity	Catalysis of the reaction: butane + O2 + NAD(P)H + H+ = butanol + NAD(P)+ + H2O.	tmpzr1t_l9r_go_relaxed.owl	sBMO|soluble butane monooxygenase							bf	2012-03-29T10:42:07Z					molecular_function											owl:Class	
GO:0016713	biolink:NamedThing	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen	Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from reduced iron-sulfur protein and one other donor, and one atom of oxygen is incorporated into one donor.	tmpzr1t_l9r_go_relaxed.owl	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulphur protein as one donor, and incorporation of one atom of oxygen				EC:1.14.15.-									molecular_function											owl:Class	
GO:0060045	biolink:NamedThing	positive regulation of cardiac muscle cell proliferation	Any process that activates or increases the frequency, rate or extent of cardiac muscle cell proliferation.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of heart muscle cell proliferation													biological_process											owl:Class	
GO:0014060	biolink:NamedThing	regulation of epinephrine secretion	Any process that modulates the frequency, rate or extent of the regulated release of epinephrine.	tmpzr1t_l9r_go_relaxed.owl	regulation of adrenaline secretion													biological_process											owl:Class	
GO:0050433	biolink:NamedThing	regulation of catecholamine secretion	Any process that modulates the frequency, rate or extent of the regulated release of catecholamines.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0034045	biolink:NamedThing	phagophore assembly site membrane	A cellular membrane associated with the phagophore assembly site.	tmpzr1t_l9r_go_relaxed.owl	isolation membrane|pre-autophagosomal structure membrane|PAS membrane|phagophore													cellular_component											owl:Class	
GO:0016020	biolink:NamedThing	membrane	A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.	tmpzr1t_l9r_go_relaxed.owl	region of membrane|membrane region|whole membrane				Wikipedia:Biological_membrane				2014-03-06T11:37:54Z			GO:0098589|GO:0098805		cellular_component											owl:Class	
GO:0045864	biolink:NamedThing	positive regulation of pteridine metabolic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving pteridine.	tmpzr1t_l9r_go_relaxed.owl	upregulation of pteridine metabolic process|up regulation of pteridine metabolic process|stimulation of pteridine metabolic process|activation of pteridine metabolic process|positive regulation of pteridine metabolism|up-regulation of pteridine metabolic process													biological_process											owl:Class	
GO:0090149	biolink:NamedThing	mitochondrial membrane fission	A process that is carried out at the cellular level which results in the separation of a single continuous mitochondrial membrane into two membranes and contributes to mitochondrial fission.	tmpzr1t_l9r_go_relaxed.owl	mitochondrial membrane scission|membrane fission involved in mitochondrial fission							tb	2009-12-08T03:08:57Z					biological_process											owl:Class	
GO:0090148	biolink:NamedThing	membrane fission	A process that is carried out at the cellular level which results in the separation of a single continuous membrane into two membranes.	tmpzr1t_l9r_go_relaxed.owl	membrane scission							tb	2009-12-08T03:06:36Z					biological_process											owl:Class	
GO:1903293	biolink:NamedThing	phosphatase complex	A protein complex which is capable of phosphatase activity.	tmpzr1t_l9r_go_relaxed.owl						An example of this is PTEN in human (P60484) in PMID:24766807 (inferred from direct assay).		bhm	2014-08-13T10:25:32Z					cellular_component											owl:Class	
GO:1902494	biolink:NamedThing	catalytic complex	A protein complex which is capable of catalytic activity.	tmpzr1t_l9r_go_relaxed.owl	enzyme complex							bhm	2013-11-13T16:18:47Z					cellular_component											owl:Class	
GO:0100011	biolink:NamedThing	positive regulation of fever generation by prostaglandin secretion	Any prostaglandin secretion process that positively_regulates fever generation.	tmpzr1t_l9r_go_relaxed.owl								cjm	2015-04-02T04:13:19Z					biological_process											owl:Class	
GO:0032310	biolink:NamedThing	prostaglandin secretion	The regulated release of a prostaglandin, any of a group of biologically active metabolites which contain a cyclopentane ring, from a cell or a tissue.	tmpzr1t_l9r_go_relaxed.owl	prostacyclin secretion													biological_process											owl:Class	
GO:1900589	biolink:NamedThing	violaceol I catabolic process	The chemical reactions and pathways resulting in the breakdown of violaceol I.	tmpzr1t_l9r_go_relaxed.owl	violaceol I breakdown|violaceol I degradation|violaceol I catabolism							di	2012-05-15T06:51:09Z					biological_process											owl:Class	
GO:0019614	biolink:NamedThing	catechol-containing compound catabolic process	The chemical reactions and pathways resulting in the breakdown of catechol-containing compounds. Catechol is a compound containing a pyrocatechol nucleus or substituent.	tmpzr1t_l9r_go_relaxed.owl	catechol catabolic process|catechol catabolism|catechol breakdown|catechol degradation													biological_process											owl:Class	
GO:1902965	biolink:NamedThing	regulation of protein localization to early endosome	Any process that modulates the frequency, rate or extent of protein localization to early endosome.	tmpzr1t_l9r_go_relaxed.owl	regulation of protein localization in early endosome|regulation of protein localisation in early endosome|regulation of protein localisation to early endosome							sjp	2014-05-06T09:28:24Z					biological_process											owl:Class	
GO:0000117	biolink:NamedThing	regulation of transcription involved in G2/M transition of mitotic cell cycle	Any process that regulates transcription such that the target genes are transcribed as part of the G2/M transition of the mitotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl	G2/M-specific transcription in mitotic cell cycle|regulation of transcription from RNA polymerase II promoter during G2/M transition of mitotic cell cycle													biological_process											owl:Class	
GO:0006355	biolink:NamedThing	regulation of transcription, DNA-templated	Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.	tmpzr1t_l9r_go_relaxed.owl	regulation of transcription, DNA-dependent|regulation of cellular transcription, DNA-dependent|transcriptional control|regulation of gene-specific transcription											GO:0032583|GO:0045449|GO:0061019		biological_process											owl:Class	
GO:0045824	biolink:NamedThing	negative regulation of innate immune response	Any process that stops, prevents, or reduces the frequency, rate or extent of the innate immune response.	tmpzr1t_l9r_go_relaxed.owl	down regulation of innate immune response|downregulation of innate immune response|down-regulation of innate immune response|inhibition of innate immune response													biological_process											owl:Class	
GO:0050777	biolink:NamedThing	negative regulation of immune response	Any process that stops, prevents, or reduces the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.	tmpzr1t_l9r_go_relaxed.owl	down regulation of immune response|inhibition of immune response|down-regulation of immune response|downregulation of immune response													biological_process											owl:Class	
GO:0047134	biolink:NamedThing	protein-disulfide reductase (NAD(P)) activity	Catalysis of the reaction: protein-dithiol + NAD(P)+ = protein-disulfide + NAD(P)H + H+.	tmpzr1t_l9r_go_relaxed.owl	protein disulfide reductase (NAD(P)H) activity|NAD(P)H:protein-disulfide oxidoreductase activity|protein disulfide reductase activity|protein-disulfide reductase activity|protein disulphide reductase activity|protein-disulphide reductase activity|insulin-glutathione transhydrogenase activity|disulfide reductase activity	https://github.com/geneontology/go-ontology/issues/20219			EC:1.8.1.8|MetaCyc:1.6.4.4-RXN									molecular_function											owl:Class	
GO:0016668	biolink:NamedThing	oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which a sulfur-containing group acts as a hydrogen or electron donor and reduces NAD or NADP.	tmpzr1t_l9r_go_relaxed.owl	oxidoreductase activity, acting on sulphur group of donors, NAD or NADP as acceptor|oxidoreductase activity, acting on NADH or NADPH, disulfide as acceptor|oxidoreductase activity, acting on a sulfur group of donors, NAD or NADP as acceptor|oxidoreductase activity, acting on NADH or NADPH, disulphide as acceptor				EC:1.8.1.-							GO:0016654		molecular_function											owl:Class	
GO:1900280	biolink:NamedThing	negative regulation of CD4-positive, alpha-beta T cell costimulation	Any process that stops, prevents or reduces the frequency, rate or extent of CD4-positive, alpha-beta T cell costimulation.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of CD4-positive, alpha beta T cell costimulation|down-regulation of CD4-positive, alpha beta T cell costimulation|inhibition of CD4-positive, alpha beta T cell costimulation|down regulation of CD4-positive, alpha beta T cell costimulation|downregulation of CD4-positive, alpha beta T cell costimulation							rl	2012-04-04T08:56:26Z					biological_process											owl:Class	
GO:1900279	biolink:NamedThing	regulation of CD4-positive, alpha-beta T cell costimulation	Any process that modulates the frequency, rate or extent of CD4-positive, alpha-beta T cell costimulation.	tmpzr1t_l9r_go_relaxed.owl	regulation of CD4-positive, alpha beta T cell costimulation							rl	2012-04-04T08:56:15Z					biological_process											owl:Class	
GO:0030027	biolink:NamedThing	lamellipodium	A thin sheetlike process extended by the leading edge of a migrating cell or extending cell process; contains a dense meshwork of actin filaments.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Lamellipodia									cellular_component											owl:Class	
GO:0001652	biolink:NamedThing	granular component	A structure found in the nucleolus, which contains nearly completed preribosomal particles destined for the cytoplasm.	tmpzr1t_l9r_go_relaxed.owl	pars granulosa				NIF_Subcellular:sao1217793903									cellular_component											owl:Class	
GO:0008800	biolink:NamedThing	beta-lactamase activity	Catalysis of the reaction: a beta-lactam + H2O = a substituted beta-amino acid.	tmpzr1t_l9r_go_relaxed.owl	beta-lactamase I-III|cephalosporin-beta-lactamase activity|exopenicillinase activity|beta-lactamase AME I|beta-lactamase A, B, C|penicillinase I, II|beta-lactam hydrolase activity|penicillin beta-lactamase activity|ampicillinase activity|neutrapen|penicillin amido-beta-lactamhydrolase activity				EC:3.5.2.6|RHEA:20401|MetaCyc:BETA-LACTAMASE-RXN									molecular_function											owl:Class	
GO:0016812	biolink:NamedThing	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides	Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a cyclic amide.	tmpzr1t_l9r_go_relaxed.owl					EC:3.5.2.-|Reactome:R-HSA-70906									molecular_function											owl:Class	
GO:0048631	biolink:NamedThing	regulation of skeletal muscle tissue growth	Any process that modulates the frequency, rate or extent of skeletal muscle growth.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0048638	biolink:NamedThing	regulation of developmental growth	Any process that modulates the frequency, rate or extent of developmental growth.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0002836	biolink:NamedThing	positive regulation of response to tumor cell	Any process that activates or increases the frequency, rate, or extent of a response to tumor cell.	tmpzr1t_l9r_go_relaxed.owl	up regulation of response to tumor cell|stimulation of response to tumor cell|activation of response to tumor cell|upregulation of response to tumor cell|positive regulation of response to tumour cell|up-regulation of response to tumor cell													biological_process											owl:Class	
GO:0008135	biolink:NamedThing	translation factor activity, RNA binding	Functions during translation by binding to RNA during polypeptide synthesis at the ribosome.	tmpzr1t_l9r_go_relaxed.owl	translation factor activity, nucleic acid binding													molecular_function											owl:Class	
GO:0003723	biolink:NamedThing	RNA binding	Binding to an RNA molecule or a portion thereof.	tmpzr1t_l9r_go_relaxed.owl	poly(A) RNA binding|poly(A)-RNA binding|poly-A RNA binding|base pairing with RNA				Reactome:R-HSA-203922							GO:0044822|GO:0000498		molecular_function											owl:Class	
GO:0034765	biolink:NamedThing	regulation of ion transmembrane transport	Any process that modulates the frequency, rate or extent of the directed movement of ions from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	regulation of ion membrane transport|regulation of transmembrane ion transport													biological_process											owl:Class	
GO:2000371	biolink:NamedThing	regulation of DNA topoisomerase (ATP-hydrolyzing) activity	Any process that modulates the frequency, rate or extent of DNA topoisomerase (ATP-hydrolyzing) activity.	tmpzr1t_l9r_go_relaxed.owl	regulation of DNA topoisomerase type II activity|regulation of deoxyribonucleic topoisomerase activity|regulation of deoxyribonucleate topoisomerase|regulation of DNA topoisomerase (ATP-hydrolysing)|regulation of topoisomerase|regulation of type II DNA topoisomerase activity|regulation of DNA topoisomerase IV activity|regulation of topoisomerase II|regulation of DNA topoisomerase II							mah	2011-02-09T02:35:27Z					biological_process											owl:Class	
GO:0010911	biolink:NamedThing	regulation of isomerase activity	Any process that modulates the activity of an isomerase. An isomerase catalyzes the geometric or structural changes within one molecule. Isomerase is the systematic name for any enzyme of EC class 5.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1902393	biolink:NamedThing	negative regulation of exodeoxyribonuclease activity	Any process that stops, prevents or reduces the frequency, rate or extent of exodeoxyribonuclease activity.	tmpzr1t_l9r_go_relaxed.owl	down regulation of exodeoxyribonuclease activity|downregulation of exodeoxyribonuclease activity|inhibition of exodeoxyribonuclease activity|down-regulation of exodeoxyribonuclease activity							jl	2013-09-11T14:56:23Z					biological_process											owl:Class	
GO:0051586	biolink:NamedThing	positive regulation of dopamine uptake involved in synaptic transmission	Any process that activates or increases the frequency, rate or extent of the directed movement of dopamine into a cell.	tmpzr1t_l9r_go_relaxed.owl	up regulation of dopamine uptake involved in synaptic transmission|up-regulation of dopamine uptake involved in synaptic transmission|upregulation of dopamine uptake involved in synaptic transmission|positive regulation of dopamine import involved in synaptic transmission|activation of dopamine uptake involved in synaptic transmission|stimulation of dopamine uptake involved in synaptic transmission													biological_process											owl:Class	
GO:0051944	biolink:NamedThing	positive regulation of catecholamine uptake involved in synaptic transmission	Any process that activates, maintains or increases the frequency, rate or extent of the directed movement of catecholamine neurotransmitters into a neuron or glial cell.	tmpzr1t_l9r_go_relaxed.owl	upregulation of catecholamine uptake during transmission of nerve impulse|up-regulation of catecholamine uptake during transmission of nerve impulse|positive regulation of catecholamine neurotransmitter reuptake|positive regulation of catecholamine uptake during transmission of nerve impulse|up regulation of catecholamine uptake during transmission of nerve impulse|positive regulation of catecholamine neurotransmitter uptake|activation of catecholamine uptake during transmission of nerve impulse|stimulation of catecholamine uptake during transmission of nerve impulse													biological_process											owl:Class	
GO:1902596	biolink:NamedThing	negative regulation of DNA replication origin binding	Any process that stops, prevents or reduces the frequency, rate or extent of DNA replication origin binding.	tmpzr1t_l9r_go_relaxed.owl	inhibition of DNA replication origin binding|downregulation of DNA replication origin binding|downregulation of ARS binding|down-regulation of DNA replication origin binding|down regulation of DNA replication origin binding|down-regulation of ARS binding|negative regulation of ARS binding|down regulation of ARS binding|inhibition of ARS binding							mah	2013-12-19T16:19:48Z					biological_process											owl:Class	
GO:0030394	biolink:NamedThing	fructoseglycine metabolic process	The chemical reactions and pathways involving fructoseglycine, a fructose molecule containing a glycine group in place of a hydroxyl group.	tmpzr1t_l9r_go_relaxed.owl	fructoseglycine metabolism													biological_process											owl:Class	
GO:0030549	biolink:NamedThing	acetylcholine receptor activator activity	Interacting (directly or indirectly) with acetylcholine receptors such that the proportion of receptors in the active form is increased.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0098772	biolink:NamedThing	molecular function regulator	A molecular function regulator regulates the activity of its target via non-covalent binding that does not result in covalent modification to the target. Examples of molecular function regulators include regulatory subunits of multimeric enzymes and channels. Mechanisms of regulation include allosteric changes in the target and competitive inhibition.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/20854|https://github.com/geneontology/go-ontology/issues/20862												molecular_function											owl:Class	
GO:1902810	biolink:NamedThing	negative regulation of skeletal muscle fiber differentiation	Any process that stops, prevents or reduces the frequency, rate or extent of skeletal muscle fiber differentiation.	tmpzr1t_l9r_go_relaxed.owl	down regulation of skeletal muscle fiber differentiation|down-regulation of skeletal muscle fiber differentiation|inhibition of skeletal muscle fiber differentiation|downregulation of skeletal muscle fiber differentiation							mr	2014-03-26T21:18:32Z					biological_process											owl:Class	
GO:2001015	biolink:NamedThing	negative regulation of skeletal muscle cell differentiation	Any process that stops, prevents or reduces the frequency, rate or extent of skeletal muscle cell differentiation.	tmpzr1t_l9r_go_relaxed.owl								yaf	2011-08-11T08:54:41Z					biological_process											owl:Class	
GO:0086101	biolink:NamedThing	endothelin receptor signaling pathway involved in heart process	An endothelin receptor signaling pathway which contributes to a circulatory system process carried out by the heart.	tmpzr1t_l9r_go_relaxed.owl	endothelin receptor signalling pathway involved in heart process							bf						biological_process											owl:Class	
GO:0086103	biolink:NamedThing	G protein-coupled receptor signaling pathway involved in heart process	An G protein-coupled receptor signaling pathway which contributes to a circulatory system process carried out by the heart.	tmpzr1t_l9r_go_relaxed.owl	GPCR signaling pathway involved in heart process|GPCR signaling pathway involved in cardiac process|G-protein coupled receptor signalling pathway involved in heart process|G-protein coupled receptor signaling pathway involved in heart process							bf	2012-03-19T01:28:23Z					biological_process											owl:Class	
GO:0047891	biolink:NamedThing	flavone 7-O-beta-glucosyltransferase activity	Catalysis of the reaction: UDP-glucose + 5,7,3',4'-tetrahydroxyflavone = UDP + 7-O-beta-D-glucosyl-5,7,3',4'-tetrahydroxyflavone.	tmpzr1t_l9r_go_relaxed.owl	UDPglucose-luteolin beta-D-glucosyltransferase activity|UDP-glucose:5,7,3',4'-tetrahydroxyflavone 7-O-beta-D-glucosyltransferase activity|uridine diphosphoglucose-luteolin glucosyltransferase activity|UDPglucose-apigenin beta-glucosyltransferase activity|UDPglucose:5,7,3',4'-tetrahydroxyflavone 7-O-beta-D-glucosyltransferase activity|flavone 7-O-b-glucosyltransferase activity|uridine diphosphoglucose-apigenin 7-O-glucosyltransferase activity|UDP-glucose-apigenin beta-glucosyltransferase activity|UDP-glucose-luteolin beta-D-glucosyltransferase activity				EC:2.4.1.81|RHEA:19577|MetaCyc:FLAVONE-7-O-BETA-GLUCOSYLTRANSFERASE-RXN									molecular_function											owl:Class	
GO:2000463	biolink:NamedThing	positive regulation of excitatory postsynaptic potential	Any process that enhances the establishment or increases the extent of the excitatory postsynaptic potential (EPSP) which is a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC) and makes it easier for the neuron to fire an action potential.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of EPSP|positive regulation of excitatory post-synaptic membrane potential							rl	2011-03-04T02:43:32Z					biological_process											owl:Class	
GO:0050789	biolink:NamedThing	regulation of biological process	Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.	tmpzr1t_l9r_go_relaxed.owl	regulation of physiological process											GO:0050791		biological_process											owl:Class	
GO:0090119	biolink:NamedThing	vesicle-mediated cholesterol transport	The directed movement of cholesterol, cholest-5-en-3-beta-ol, or cholesterol-containing compounds, by membrane-bounded vesicles.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-12-07T12:14:37Z					biological_process											owl:Class	
GO:0016192	biolink:NamedThing	vesicle-mediated transport	A cellular transport process in which transported substances are moved in membrane-bounded vesicles; transported substances are enclosed in the vesicle lumen or located in the vesicle membrane. The process begins with a step that directs a substance to the forming vesicle, and includes vesicle budding and coating. Vesicles are then targeted to, and fuse with, an acceptor membrane.	tmpzr1t_l9r_go_relaxed.owl	vesicle transport|nonselective vesicle transport|vesicular transport|vesicle trafficking|protein sorting along secretory pathway											GO:0006899		biological_process											owl:Class	
GO:1904289	biolink:NamedThing	regulation of mitotic DNA damage checkpoint	Any process that modulates the frequency, rate or extent of mitotic DNA damage checkpoint.	tmpzr1t_l9r_go_relaxed.owl								kmv	2015-06-09T13:03:11Z					biological_process											owl:Class	
GO:1903345	biolink:NamedThing	negative regulation of protein polyglycylation	Any process that stops, prevents or reduces the frequency, rate or extent of protein polyglycylation.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of protein polyglycylation|inhibition of protein polyglycylation|downregulation of protein polyglycylation|down regulation of protein polyglycylation							sart	2014-08-19T09:32:16Z					biological_process											owl:Class	
GO:0031400	biolink:NamedThing	negative regulation of protein modification process	Any process that stops, prevents, or reduces the frequency, rate or extent of the covalent alteration of one or more amino acid residues within a protein.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of protein modification|inhibition of protein modification|down regulation of protein modification|downregulation of protein modification													biological_process											owl:Class	
GO:0048539	biolink:NamedThing	bone marrow development	The process whose specific outcome is the progression of the bone marrow over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0009888	biolink:NamedThing	tissue development	The process whose specific outcome is the progression of a tissue over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl	histogenesis|histogenesis and organogenesis				Wikipedia:Histogenesis									biological_process											owl:Class	
GO:0061375	biolink:NamedThing	mammillotectal axonal tract development	The progression of the mammillotectal tract over time, from its formation to the mature structure. The mammillotectal tract is the collection of axons that connects the ventral diencephalon to the superior colliculus.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-11-09T09:01:14Z					biological_process											owl:Class	
GO:0103085	biolink:NamedThing	2-(5'-methylthio)pentylmalate synthase activity	Catalysis of the reaction: 2-oxo-7-methylthioheptanoate + acetyl-CoA + H2O <=> H+ + 2-(5'-methylthio)pentylmalate + coenzyme A.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXNQT-4169									molecular_function											owl:Class	
GO:0046912	biolink:NamedThing	acyltransferase, acyl groups converted into alkyl on transfer	Catalysis of the transfer of an acyl group from one compound (donor) to another (acceptor), with the acyl group being converted into alkyl on transfer.	tmpzr1t_l9r_go_relaxed.owl	transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer	https://github.com/geneontology/go-ontology/issues/20486			EC:2.3.3.-									molecular_function											owl:Class	
GO:0015787	biolink:NamedThing	UDP-glucuronic acid transmembrane transport	The directed movement of UDP-glucuronic acid into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. UDP-glucuronic acid is a substance composed of glucuronic acid in glycosidic linkage with uridine diphosphate.	tmpzr1t_l9r_go_relaxed.owl	UDP-glucuronic acid transport													biological_process											owl:Class	
GO:0090481	biolink:NamedThing	pyrimidine nucleotide-sugar transmembrane transport	The process in which a pyrimidine nucleotide-sugar is transported across a membrane. Pyrimidine nucleotide-sugars are pyrimidine nucleotides in glycosidic linkage with a monosaccharide or monosaccharide derivative.	tmpzr1t_l9r_go_relaxed.owl	pyrimidine nucleotide-sugar membrane transport|pyrimidine nucleotide-sugar transport					Note that this term is not intended for use in annotating lateral movement within membranes.		tb	2012-10-01T16:43:54Z			GO:0015781		biological_process											owl:Class	
GO:1990089	biolink:NamedThing	response to nerve growth factor	A process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nerve growth factor stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to nerve growth factor stimulus							sl	2013-05-06T17:08:47Z					biological_process											owl:Class	
GO:0008513	biolink:NamedThing	secondary active organic cation transmembrane transporter activity	Enables the transfer of organic cations from one side of a membrane to the other, up the solute's concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction.	tmpzr1t_l9r_go_relaxed.owl	polyspecific organic cation transmembrane transporter activity|organic cation porter activity				Reactome:R-HSA-549241							GO:0015354		molecular_function											owl:Class	
GO:0015291	biolink:NamedThing	secondary active transmembrane transporter activity	Enables the transfer of a solute from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy, not direct ATP coupling. Secondary active transporters include symporters and antiporters.	tmpzr1t_l9r_go_relaxed.owl	nitrite/nitrate porter activity|coupled carrier|porters|electrochemical potential-driven transporter activity|secondary carrier-type facilitators|energizer of outer membrane receptor-mediated transport activity|porter activity|ion-gradient-driven energizer activity|multidrug endosomal transmembrane transporter activity|active transporter|heavy metal ion porter activity|galactose/glucose (methylgalactoside) porter activity				TC:2.A|Reactome:R-HSA-199216							GO:0015570|GO:0015290|GO:0015353|GO:0015404		molecular_function											owl:Class	
GO:0009416	biolink:NamedThing	response to light stimulus	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light stimulus, electromagnetic radiation of wavelengths classified as infrared, visible or ultraviolet light.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0009314	biolink:NamedThing	response to radiation	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electromagnetic radiation stimulus. Electromagnetic radiation is a propagating wave in space with electric and magnetic components. These components oscillate at right angles to each other and to the direction of propagation.	tmpzr1t_l9r_go_relaxed.owl	response to electromagnetic radiation stimulus|response to radiation stimulus					Note that 'radiation' refers to electromagnetic radiation of any wavelength.								biological_process											owl:Class	
GO:1901622	biolink:NamedThing	positive regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning	Any process that activates or increases the frequency, rate or extent of smoothened signaling pathway involved in dorsal/ventral neural tube patterning.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of smoothened signalling pathway involved in dorsal/ventral neural tube patterning|activation of hh signaling pathway involved in dorsal/ventral neural tube patterning|positive regulation of hh signaling pathway involved in dorsal/ventral neural tube patterning|upregulation of hedgehog signaling pathway involved in dorsal/ventral neural tube patterning|up regulation of hh signaling pathway involved in dorsal/ventral neural tube patterning|up regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning|activation of hedgehog signaling pathway involved in dorsal/ventral neural tube patterning|upregulation of smoothened signalling pathway involved in dorsal/ventral neural tube patterning|activation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning|positive regulation of smoothened signalling pathway involved in dorsal/ventral neural tube patterning|up-regulation of hedgehog signaling pathway involved in dorsal/ventral neural tube patterning|up regulation of hedgehog signaling pathway involved in dorsal/ventral neural tube patterning|activation of smoothened signalling pathway involved in dorsal/ventral neural tube patterning|upregulation of hh signaling pathway involved in dorsal/ventral neural tube patterning|positive regulation of hedgehog signaling pathway involved in dorsal/ventral neural tube patterning|up-regulation of hh signaling pathway involved in dorsal/ventral neural tube patterning|upregulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning|up regulation of smoothened signalling pathway involved in dorsal/ventral neural tube patterning|up-regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning							krc	2012-11-13T20:12:06Z					biological_process											owl:Class	
GO:0043330	biolink:NamedThing	response to exogenous dsRNA	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an exogenous double-stranded RNA stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to exogenous double-stranded RNA|response to viral dsRNA					Note that the presence of exogenous double-stranded RNA is usually indicative of a viral infection. Consider also annotating to 'response to virus ; GO:0009615'.								biological_process											owl:Class	
GO:0043331	biolink:NamedThing	response to dsRNA	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a double-stranded RNA stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to double-stranded RNA													biological_process											owl:Class	
GO:0009211	biolink:NamedThing	pyrimidine deoxyribonucleoside triphosphate metabolic process	The chemical reactions and pathways involving pyrimidine deoxyribonucleoside triphosphate, a compound consisting of a pyrimidine base linked to a deoxyribose sugar esterified with triphosphate on the sugar.	tmpzr1t_l9r_go_relaxed.owl	pyrimidine deoxyribonucleoside triphosphate metabolism													biological_process											owl:Class	
GO:0009147	biolink:NamedThing	pyrimidine nucleoside triphosphate metabolic process	The chemical reactions and pathways involving pyrimidine nucleoside triphosphate, a compound consisting of a pyrimidine base linked to a ribose or deoxyribose sugar esterified with triphosphate on the sugar.	tmpzr1t_l9r_go_relaxed.owl	pyrimidine nucleoside triphosphate metabolism													biological_process											owl:Class	
GO:0061960	biolink:NamedThing	regulation of heme oxygenase activity	Any process that modulates the frequency, or rate of heme oxygenase activity.	tmpzr1t_l9r_go_relaxed.owl								dph	2018-01-22T20:24:06Z					biological_process											owl:Class	
GO:0098524	biolink:NamedThing	neuromuscular junction of somatic muscle myotube	A neuromuscular junction in which the target muscle cell is a somatic muscle myotube, such as an arthropod somatic muscle cell.	tmpzr1t_l9r_go_relaxed.owl								dos	2013-10-14T12:05:43Z					cellular_component											owl:Class	
GO:0098523	biolink:NamedThing	neuromuscular junction of myotube	A neuromuscular junction in which the target muscle cell is a myotube.	tmpzr1t_l9r_go_relaxed.owl						In vertebrates, the term 'neuromuscular junction' is limited to synapses targeting the myotubes of skeletal muscle (AKA skeletal muscle fibers). Neuromuscular junctions targeting other muscle cell types exist in invertebrates such as the mononucleate somatic muscles of nematodes.		dos	2013-10-14T12:05:12Z					cellular_component											owl:Class	
GO:0016557	biolink:NamedThing	peroxisome membrane biogenesis	The process in which a peroxisome membrane is synthesized, aggregates, and bonds together.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0044091	biolink:NamedThing	membrane biogenesis	A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a membrane.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0102781	biolink:NamedThing	isofucosterol hydroxylase activity	Catalysis of the reaction: H+ + isofucosterol + O2 + NADPH <=> (22alpha)-hydroxy-isofucosterol + H2O + NADP.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-7877									molecular_function											owl:Class	
GO:1902179	biolink:NamedThing	verruculogen metabolic process	The chemical reactions and pathways involving verruculogen.	tmpzr1t_l9r_go_relaxed.owl	verruculogen metabolism							di	2013-05-30T17:44:25Z					biological_process											owl:Class	
GO:0035834	biolink:NamedThing	indole alkaloid metabolic process	The chemical reactions and pathways involving an indole alkaloid, an alkaloid containing an indole skeleton.	tmpzr1t_l9r_go_relaxed.owl	indole alkaloid metabolism							bf	2011-05-04T03:17:44Z					biological_process											owl:Class	
GO:0070873	biolink:NamedThing	regulation of glycogen metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving glycogen.	tmpzr1t_l9r_go_relaxed.owl	regulation of glycogen metabolism							mah	2009-08-20T02:44:53Z					biological_process											owl:Class	
GO:0090615	biolink:NamedThing	mitochondrial mRNA processing	Steps involved in processing precursor RNAs arising from transcription of operons in the mitochondrial genome into mature mRNAs.	tmpzr1t_l9r_go_relaxed.owl								tb	2014-10-24T12:43:27Z					biological_process											owl:Class	
GO:0000963	biolink:NamedThing	mitochondrial RNA processing	The conversion of a primary RNA molecule transcribed from a mitochondrial genome into one or more mature RNA molecules; occurs in the mitochondrion.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1901281	biolink:NamedThing	fructoselysine catabolic process	The chemical reactions and pathways resulting in the breakdown of fructoselysine.	tmpzr1t_l9r_go_relaxed.owl	fructosyllysine breakdown|fructosyllysine catabolism|fructosyllysine degradation|fructosyllysine catabolic process							yaf	2012-08-17T15:04:43Z					biological_process											owl:Class	
GO:0030393	biolink:NamedThing	fructoselysine metabolic process	The chemical reactions and pathways involving fructoselysine, a fructose molecule containing a lysine group in place of a hydroxyl group.	tmpzr1t_l9r_go_relaxed.owl	fructoselysine metabolism													biological_process											owl:Class	
GO:0072745	biolink:NamedThing	cellular response to antimycin A	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antimycin A stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2012-08-31T12:31:08Z					biological_process											owl:Class	
GO:0008150	biolink:NamedThing	biological_process	A biological process represents a specific objective that the organism is genetically programmed to achieve. Biological processes are often described by their outcome or ending state, e.g., the biological process of cell division results in the creation of two daughter cells (a divided cell) from a single parent cell. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence.	tmpzr1t_l9r_go_relaxed.owl	single-organism process|biological process|physiological process|single organism process				Wikipedia:Biological_process	Note that, in addition to forming the root of the biological process ontology, this term is recommended for use for the annotation of gene products whose biological process is unknown. When this term is used for annotation, it indicates that no information was available about the biological process of the gene product annotated as of the date the annotation was made; the evidence code 'no data' (ND), is used to indicate this.		jl	2012-09-19T15:05:24Z			GO:0000004|GO:0007582|GO:0044699		biological_process											owl:Class	
GO:0047877	biolink:NamedThing	ephedrine dehydrogenase activity	Catalysis of the reaction: (1R,2S)-ephedrine + NAD(+) = (R)-2-methylimino-1-phenylpropan-1-ol + 2 H(+) + NADH.	tmpzr1t_l9r_go_relaxed.owl	(-)-ephedrine:NAD+ 2-oxidoreductase activity				EC:1.5.1.18|MetaCyc:EPHEDRINE-DEHYDROGENASE-RXN|RHEA:16289|KEGG_REACTION:R03614									molecular_function											owl:Class	
GO:0061348	biolink:NamedThing	planar cell polarity pathway involved in ventricular septum morphogenesis	The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors including C-Jun N-terminal kinase (JNK) to modulate cytoskeletal elements and control cell polarity that contributes to the shaping of the ventricular septum.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-10-01T10:47:49Z					biological_process											owl:Class	
GO:0061346	biolink:NamedThing	planar cell polarity pathway involved in heart morphogenesis	The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors including C-Jun N-terminal kinase (JNK) to modulate cytoskeletal elements and control cell polarity that contributes to the shaping of the heart.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-09-30T12:47:24Z					biological_process											owl:Class	
GO:0003278	biolink:NamedThing	apoptotic process involved in heart morphogenesis	Any apoptotic process that contributes to the shaping of the heart.	tmpzr1t_l9r_go_relaxed.owl	apoptosis involved in heart morphogenesis							dph	2009-10-20T09:40:22Z					biological_process											owl:Class	
GO:0006915	biolink:NamedThing	apoptotic process	A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathway phase) which trigger an execution phase. The execution phase is the last step of an apoptotic process, and is typically characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died.	tmpzr1t_l9r_go_relaxed.owl	activation of apoptosis|apoptotic cell death|induction of apoptosis by p53|apoptosis activator activity|apoptotic program|signaling (initiator) caspase activity|caspase-dependent programmed cell death|programmed cell death by apoptosis|apoptosis signaling|cellular suicide|commitment to apoptosis|cell suicide|apoptotic programmed cell death|induction of apoptosis|apoptosis|type I programmed cell death				Wikipedia:Apoptosis							GO:0008632|GO:0006917		biological_process											owl:Class	
GO:0009912	biolink:NamedThing	auditory receptor cell fate commitment	The process in which the cellular identity of auditory hair cells is acquired and determined.	tmpzr1t_l9r_go_relaxed.owl	auditory hair cell fate commitment													biological_process											owl:Class	
GO:0060120	biolink:NamedThing	inner ear receptor cell fate commitment	The process in which a cell becomes committed to become an inner ear receptor cell.	tmpzr1t_l9r_go_relaxed.owl	inner ear hair cell fate commitment													biological_process											owl:Class	
GO:0044858	biolink:NamedThing	plasma membrane raft polarization	The clustering and aggregation of a plasma membrane into domains. This serves as a mechanism to compartmentalize cellular activities and to establish cell polarity.	tmpzr1t_l9r_go_relaxed.owl	plasma membrane polarization							jl	2014-07-23T16:21:39Z					biological_process											owl:Class	
GO:0044855	biolink:NamedThing	plasma membrane raft distribution	The process that establishes the spatial arrangement of membrane rafts within a plasma membrane.	tmpzr1t_l9r_go_relaxed.owl								jl	2014-07-23T16:00:41Z					biological_process											owl:Class	
GO:0072159	biolink:NamedThing	epithelial cell migration involved in proximal tubule morphogenesis	The orderly movement of epithelial cells within a renal tubule that contributes to proximal tubule morphogenesis.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-02-24T02:37:08Z					biological_process											owl:Class	
GO:0010631	biolink:NamedThing	epithelial cell migration	The orderly movement of an epithelial cell from one site to another, often during the development of a multicellular organism.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1900054	biolink:NamedThing	positive regulation of retinoic acid biosynthetic process	Any process that activates or increases the frequency, rate or extent of retinoic acid biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	up regulation of retinoic acid biosynthetic process|up regulation of retinoic acid anabolic process|up-regulation of retinoic acid anabolic process|up-regulation of retinoic acid biosynthetic process|upregulation of retinoic acid anabolic process|upregulation of retinoic acid biosynthetic process|positive regulation of retinoic acid anabolic process|activation of retinoic acid anabolic process|activation of retinoic acid biosynthetic process							yaf	2012-01-20T09:55:52Z					biological_process											owl:Class	
GO:0001099	biolink:NamedThing	basal RNA polymerase II transcription machinery binding	Binding to a component of the basal transcription machinery for RNA polymerase II which is composed of the RNA polymerase II core enzyme, a multisubunit eukaryotic nuclear RNA polymerase typically composed of twelve subunits, and the basal RNA polymerase II transcription factors, the minimal set of factors required for formation of the preinitiation complex (PIC) by the RNA polymerase.	tmpzr1t_l9r_go_relaxed.owl	basal RNAP II transcription machinery binding					Note that the definition of basal, or general, transcription factors has typically been done at a small number of well characterized activator-independent promoters. At an activator-dependent promoter, one or more additional factors are generally required in addition to the basal factors.		krc	2010-11-24T12:54:33Z					molecular_function											owl:Class	
GO:0001098	biolink:NamedThing	basal transcription machinery binding	Binding to a component of the basal transcription machinery which is composed of the RNA polymerase core enzyme and the basal transcription factor(s), the minimal set of factors required for formation of the preinitiation complex (PIC) by the RNA polymerase.	tmpzr1t_l9r_go_relaxed.owl						Note that the definition of basal, or general, transcription factors has typically been done at a small number of well characterized activator-independent promoters. At an activator-dependent promoter, one or more additional factors are generally required in addition to the basal factors.		krc	2010-11-24T12:50:49Z					molecular_function											owl:Class	
GO:0009239	biolink:NamedThing	enterobactin biosynthetic process	The chemical reactions and pathways resulting in the formation of enterobactin, a catechol-derived siderochrome of Enterobacteria; enterobactin (N',N',N''-(2,6,10-trioxo-1,5,9-triacyclodecane-3,7,11-triyl)tris(2,3-dihydroxy)benzamide) is a self-triester of 2,3-dihydroxy-N-benzoyl-L-serine and a product of the shikimate pathway.	tmpzr1t_l9r_go_relaxed.owl	enterochelin biosynthesis|enterobactin formation|enterobactin anabolism|enterobactin synthetase|enterobactin synthesis|enterobactin biosynthesis|enterobactin biosynthetic process, peptide modification|enterochelin biosynthetic process|enterobactin biosynthetic process, peptide formation				MetaCyc:ENTBACSYN-PWY							GO:0031191|GO:0031192		biological_process											owl:Class	
GO:0009238	biolink:NamedThing	enterobactin metabolic process	The chemical reactions and pathways involving enterobactin, a catechol-derived siderochrome of Enterobacteria; enterobactin (N',N',N''-(2,6,10-trioxo-1,5,9-triacyclodecane-3,7,11-triyl)tris(2,3-dihydroxy)benzamide) is a self-triester of 2,3-dihydroxy-N-benzoyl-L-serine and a product of the shikimate pathway.	tmpzr1t_l9r_go_relaxed.owl	enterobactin metabolism|enterochelin metabolic process|enterochelin metabolism													biological_process											owl:Class	
GO:0051776	biolink:NamedThing	detection of redox state	The series of events in which a chemical stimulus indicating redox state is received and converted into a molecular signal. Redox state refers to the balance of oxidized versus reduced forms of electron donors and acceptors in an organelle, cell or organ; plastoquinone, glutathione (GSH/GSSG), and nicotinamide nucleotides (NAD+/NADH and NADP+/NADPH) are among the most important.	tmpzr1t_l9r_go_relaxed.owl	redox sensing													biological_process											owl:Class	
GO:0051775	biolink:NamedThing	response to redox state	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating redox state. Redox state refers to the balance of oxidized versus reduced forms of electron donors and acceptors in an organelle, cell or organ; plastoquinone, glutathione (GSH/GSSG), and nicotinamide nucleotides (NAD+/NADH and NADP+/NADPH) are among the most important.	tmpzr1t_l9r_go_relaxed.owl	redox signal response											GO:0006980		biological_process											owl:Class	
GO:1900112	biolink:NamedThing	regulation of histone H3-K9 trimethylation	Any process that modulates the frequency, rate or extent of histone H3-K9 trimethylation.	tmpzr1t_l9r_go_relaxed.owl								bf	2012-02-21T09:09:49Z					biological_process											owl:Class	
GO:1901479	biolink:NamedThing	benomyl transmembrane transporter activity	Enables the transfer of benomyl from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	benomyl transporter activity							tb	2012-10-04T23:21:10Z			GO:0015242		molecular_function											owl:Class	
GO:0042887	biolink:NamedThing	amide transmembrane transporter activity	Enables the transfer of an amide, any compound containing one, two, or three acyl groups attached to a nitrogen atom, from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	amine/amide/polyamine channel activity													molecular_function											owl:Class	
GO:0047499	biolink:NamedThing	calcium-independent phospholipase A2 activity	Catalysis of the reaction: phosphatidylcholine + H2O = 1-acylglycerophosphocholine + a carboxylate. This reaction does not require Ca2+.	tmpzr1t_l9r_go_relaxed.owl	calcium-independent cytosolic phospholipase A2 activity				Reactome:R-HSA-8952251									molecular_function											owl:Class	
GO:0004623	biolink:NamedThing	phospholipase A2 activity	Catalysis of the reaction: a 1,2-diacyl-sn-glycero-3-phospholipid + H2O = 1-acyl-sn-glycero-3-phospholipid + a fatty acid. This reaction removes the fatty acid attached to the sn2-position. Substrates include phosphatidylcholine, phosphatidylethanolamine, choline plasmalogen and phosphatides.	tmpzr1t_l9r_go_relaxed.owl	lecithinase A activity|phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine)|phosphatidase activity|phosphatidylcholine 2-acylhydrolase activity|secreted phospholipase A2 activity|phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine)|cytosolic phospholipase A2 activity|phosphatidolipase activity	https://github.com/geneontology/go-ontology/issues/21259			EC:3.1.1.4|Reactome:R-HSA-1602398|RHEA:15801|MetaCyc:RXN-15067|Reactome:R-HSA-1482656|Reactome:R-HSA-1482897|Reactome:R-HSA-1482759|Reactome:R-HSA-1482816|Reactome:R-HSA-1482778|Reactome:R-HSA-1602374|Reactome:R-HSA-1482884|Reactome:R-HSA-1482825|Reactome:R-HSA-1482907|Reactome:R-HSA-8848484|Reactome:R-HSA-1482887|Reactome:R-HSA-1602417|Reactome:R-HSA-1482856|Reactome:R-HSA-1482745|Reactome:R-HSA-1482604|Reactome:R-HSA-1602399|Reactome:R-HSA-1482900|Reactome:R-HSA-1482771|Reactome:R-HSA-1602368|Reactome:R-HSA-1602446|MetaCyc:PHOSPHOLIPASE-A2-RXN|Reactome:R-HSA-1482868|Reactome:R-HSA-1482679|Reactome:R-HSA-1602377|Reactome:R-HSA-1482776							GO:0102568|GO:0102567		molecular_function											owl:Class	
GO:0051778	biolink:NamedThing	ent-7-alpha-hydroxykaurenoate oxidase activity	Catalysis of the reaction: ent-7-alpha-hydroxykaurenoate + NADPH + H+ + O2 = gibberellin 12-aldehyde + NADP+ + 2 H2O. This is the second of three successive reactions resulting in the oxidation of ent-kaurenoate (ent-kaurenoic acid) to gibberellin 12 (GA12).	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN1F-160|RHEA:22904	Note that the enzyme ent-kaurenoate oxidase also catalyzes the reactions represented by the molecular function terms 'ent-kaurenoate oxidase activity ; GO:0051777' and 'gibberellin 12-aldehyde oxidase activity ; GO:0051779'.								molecular_function											owl:Class	
GO:0036268	biolink:NamedThing	swimming	Self-propelled movement of an organism from one location to another through water, often by means of active fin movement.	tmpzr1t_l9r_go_relaxed.owl						For behavioral aspects of swimming, consider instead annotating to 'swimming behavior ; GO:0036269'.		bf	2012-07-04T10:12:24Z					biological_process											owl:Class	
GO:0040011	biolink:NamedThing	locomotion	Self-propelled movement of a cell or organism from one location to another.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0050667	biolink:NamedThing	homocysteine metabolic process	The chemical reactions and pathways involving homocysteine, the amino acid alpha-amino-gamma-mercaptobutanoic acid. Homocysteine is an important intermediate in the metabolic reactions of its S-methyl derivative, methionine.	tmpzr1t_l9r_go_relaxed.owl	Hcy metabolism|Hcy metabolic process|homocysteine metabolism													biological_process											owl:Class	
GO:0000096	biolink:NamedThing	sulfur amino acid metabolic process	The chemical reactions and pathways involving amino acids containing sulfur, comprising cysteine, homocysteine, methionine and selenocysteine.	tmpzr1t_l9r_go_relaxed.owl	sulfur amino acid metabolism|sulphur amino acid metabolic process|sulphur amino acid metabolism													biological_process											owl:Class	
GO:0120294	biolink:NamedThing	peptide serotonyltransferase activity	Catalysis of the reaction: L-glutaminyl-[protein] + serotonin = 5-serotonyl-L-glutamyl-[protein] + NH4(+).	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/20685			RHEA:66552			krc	2021-01-19T02:07:56Z					molecular_function											owl:Class	
GO:0106303	biolink:NamedThing	mannogen metabolic process	The chemical reactions and pathways involving mannogen, a mannose-containing polysaccharide that is a major energy reserve in Leishmania.	tmpzr1t_l9r_go_relaxed.owl	beta-1,2-mannan metabolic process|mannogen metabolism							hjd	2020-09-09T13:49:42Z					biological_process											owl:Class	
GO:0044264	biolink:NamedThing	cellular polysaccharide metabolic process	The chemical reactions and pathways involving polysaccharides, polymers of more than 10 monosaccharide residues joined by glycosidic linkages, as carried out by individual cells.	tmpzr1t_l9r_go_relaxed.owl	cellular glycan metabolism|cellular glycan metabolic process|cellular polysaccharide metabolism													biological_process											owl:Class	
GO:0060170	biolink:NamedThing	ciliary membrane	The portion of the plasma membrane surrounding a cilium.	tmpzr1t_l9r_go_relaxed.owl	cilium membrane|flagellum membrane|cilial membrane|flagellar membrane					Note that cilia and eukaryotic flagella are deemed to be equivalent.						GO:0020017		cellular_component											owl:Class	
GO:0010064	biolink:NamedThing	embryonic shoot morphogenesis	The process in which the anatomical structures of embryonic shoot are generated and organized.	tmpzr1t_l9r_go_relaxed.owl	primary shoot system morphogenesis													biological_process											owl:Class	
GO:0010016	biolink:NamedThing	shoot system morphogenesis	The process in which the anatomical structures of the shoot are generated and organized. The shoot is the part of a seed plant body that is usually above ground.	tmpzr1t_l9r_go_relaxed.owl	shoot morphogenesis													biological_process											owl:Class	
GO:0075321	biolink:NamedThing	oomycete sporangium development	The process that leads to the development of an oomycete sporangium, a single-celled or many-celled structure that germinates directly to form an infection hypha or differentiates, through specialized cleavage vesicles, into between 10 and 30 zoospores, which are laterally flagellated.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0001882	biolink:NamedThing	nucleoside binding	Binding to a nucleoside, a compound consisting of a purine or pyrimidine nitrogenous base linked either to ribose or deoxyribose.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0036094	biolink:NamedThing	small molecule binding	Binding to a small molecule, any low molecular weight, monomeric, non-encoded molecule.	tmpzr1t_l9r_go_relaxed.owl						Small molecules in GO include monosaccharides but exclude disaccharides and polysaccharides.		bf	2012-01-17T04:20:34Z					molecular_function											owl:Class	
GO:1905261	biolink:NamedThing	regulation of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination	Any process that modulates the frequency, rate or extent of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination.	tmpzr1t_l9r_go_relaxed.owl								se	2016-06-13T20:45:02Z					biological_process											owl:Class	
GO:1903341	biolink:NamedThing	regulation of meiotic DNA double-strand break formation	Any process that modulates the frequency, rate or extent of meiotic DNA double-strand break formation.	tmpzr1t_l9r_go_relaxed.owl								mcc	2014-08-18T21:31:54Z					biological_process											owl:Class	
GO:1904498	biolink:NamedThing	protein localization to mitotic actomyosin contractile ring	Any protein localization to actomyosin contractile ring that is involved in mitotic cytokinesis.	tmpzr1t_l9r_go_relaxed.owl	protein localisation to actomyosin contractile ring involved in cytokinesis after mitosis|protein localisation to actomyosin contractile ring involved in mitotic cytokinesis|protein localization to actomyosin contractile ring during mitotic cytokinesis|protein localization to actomyosin contractile ring involved in cytokinesis after mitosis|protein localization to actomyosin contractile ring involved in mitotic cytokinesis							mah	2015-07-22T14:30:57Z					biological_process											owl:Class	
GO:0042076	biolink:NamedThing	protein phosphate-linked glycosylation	The glycosylation of peptidyl-amino acids through a phosphoester bond forming, for example, GlcNAc-alpha-1-P-Ser residues.	tmpzr1t_l9r_go_relaxed.owl	protein amino acid phosphate-linked glycosylation|phosphoglycosylation													biological_process											owl:Class	
GO:0006486	biolink:NamedThing	protein glycosylation	A protein modification process that results in the addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid, e.g. the addition of glycan chains to proteins.	tmpzr1t_l9r_go_relaxed.owl	protein amino acid glycosylation|protein-carbohydrate complex assembly											GO:0065006		biological_process											owl:Class	
GO:0051234	biolink:NamedThing	establishment of localization	Any process that localizes a substance or cellular component. This may occur via movement, tethering or selective degradation.	tmpzr1t_l9r_go_relaxed.owl	establishment of localisation													biological_process											owl:Class	
GO:0007512	biolink:NamedThing	adult heart development	The process whose specific outcome is the progression of the adult heart over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl	adult cardiac development													biological_process											owl:Class	
GO:0007507	biolink:NamedThing	heart development	The process whose specific outcome is the progression of the heart over time, from its formation to the mature structure. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.	tmpzr1t_l9r_go_relaxed.owl	cardiac development|dorsal vessel development				Wikipedia:Heart_development							GO:0007511		biological_process											owl:Class	
GO:0046433	biolink:NamedThing	2-aminoethylphosphonate metabolic process	The chemical reactions and pathways involving 2-aminoethylphosphonate, most abundant and ubiquitous of naturally occurring phosphonates. It is typically found as a conjugate of glycans, lipids, and proteins, which in turn perform essential biochemical functions in specialized lower organisms.	tmpzr1t_l9r_go_relaxed.owl	ciliatine metabolism|2-phosphonoethylamine metabolic process|2-aminoethylphosphonate metabolism|ciliatine metabolic process|2-phosphonoethylamine metabolism													biological_process											owl:Class	
GO:0007516	biolink:NamedThing	hemocyte development	The process whose specific outcome is the progression of the hemocyte over time, from its formation to the mature structure. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen.	tmpzr1t_l9r_go_relaxed.owl	arthropod blood cell development													biological_process											owl:Class	
GO:0048468	biolink:NamedThing	cell development	The process whose specific outcome is the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate.	tmpzr1t_l9r_go_relaxed.owl	terminal differentiation													biological_process											owl:Class	
GO:0008765	biolink:NamedThing	UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase activity	Catalysis of the reaction: meso-2,6-diaminopimelate + ATP + UDP-N-acetylmuramoyl-L-alanyl-D-glutamate = ADP + 2 H(+) + phosphate + UDP-N-acetylmuramoyl-L-alanyl-D-gamma-glutamyl-meso-2,6-diaminoheptanedioate.	tmpzr1t_l9r_go_relaxed.owl	UDP-N-acetylmuramyl-tripeptide synthetase activity|UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelate synthetase activity|UDP-N-acetylmuramoyl-L-alanyl-D-glutamate:(L)-meso-2,6-diaminoheptanedioate gamma-ligase (ADP-forming)|UDP-N-acetylmuramoyl-L-alanyl-D-glutamate:meso-2,6-diamino-heptanedioate ligase (ADP-forming) activity|MurE synthetase activity				MetaCyc:UDP-NACMURALGLDAPLIG-RXN|RHEA:23676|EC:6.3.2.13|KEGG_REACTION:R02788									molecular_function											owl:Class	
GO:0016881	biolink:NamedThing	acid-amino acid ligase activity	Catalysis of the ligation of an acid to an amino acid via a carbon-nitrogen bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.	tmpzr1t_l9r_go_relaxed.owl	peptide synthase activity				EC:6.3.2.-									molecular_function											owl:Class	
GO:0031669	biolink:NamedThing	cellular response to nutrient levels	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of nutrients.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0031668	biolink:NamedThing	cellular response to extracellular stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an extracellular stimulus.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1903267	biolink:NamedThing	negative regulation of ornithine catabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of ornithine catabolic process.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of ornithine degradation|down-regulation of ornithine breakdown|down-regulation of ornithine catabolism|downregulation of ornithine catabolic process|down regulation of ornithine breakdown|negative regulation of ornithine degradation|inhibition of ornithine degradation|down-regulation of ornithine catabolic process|negative regulation of ornithine breakdown|inhibition of ornithine catabolic process|negative regulation of ornithine catabolism|down regulation of ornithine catabolic process|down regulation of ornithine degradation|downregulation of ornithine catabolism|inhibition of ornithine catabolism|inhibition of ornithine breakdown|downregulation of ornithine degradation|downregulation of ornithine breakdown|down regulation of ornithine catabolism					An example of this is ARGI in Saccharomyces cerevisiae (P00812) in PMID:12679340 (inferred from direct assay).		bhm	2014-08-08T08:29:42Z					biological_process											owl:Class	
GO:1903266	biolink:NamedThing	regulation of ornithine catabolic process	Any process that modulates the frequency, rate or extent of ornithine catabolic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of ornithine breakdown|regulation of ornithine degradation|regulation of ornithine catabolism					An example of this is ARGI in Saccharomyces cerevisiae (P00812) in PMID:12679340 (inferred from direct assay).		bhm	2014-08-08T08:29:33Z					biological_process											owl:Class	
GO:0051094	biolink:NamedThing	positive regulation of developmental process	Any process that activates or increases the rate or extent of development, the biological process whose specific outcome is the progression of an organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).	tmpzr1t_l9r_go_relaxed.owl	activation of developmental process|stimulation of developmental process|up-regulation of developmental process|up regulation of developmental process|upregulation of developmental process													biological_process											owl:Class	
GO:0045220	biolink:NamedThing	positive regulation of FasL production	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of FasL.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of FasL biosynthesis|stimulation of FasL biosynthetic process|positive regulation of FasL synthesis|positive regulation of FasL anabolism|up-regulation of FasL biosynthetic process|upregulation of FasL biosynthetic process|positive regulation of FasL formation|positive regulation of FasL biosynthetic process|up regulation of FasL biosynthetic process|activation of FasL biosynthetic process													biological_process											owl:Class	
GO:0030243	biolink:NamedThing	cellulose metabolic process	The chemical reactions and pathways involving cellulose, a linear beta1-4 glucan of molecular mass 50-400 kDa with the pyranose units in the -4C1 conformation.	tmpzr1t_l9r_go_relaxed.owl	cellulose metabolism											GO:0016177		biological_process											owl:Class	
GO:0051273	biolink:NamedThing	beta-glucan metabolic process	The chemical reactions and pathways involving beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds.	tmpzr1t_l9r_go_relaxed.owl	beta-glucan metabolism													biological_process											owl:Class	
GO:0033260	biolink:NamedThing	nuclear DNA replication	The DNA-dependent DNA replication that occurs in the nucleus of eukaryotic organisms as part of the cell cycle.	tmpzr1t_l9r_go_relaxed.owl	DNA replication during S phase|DNA replication involved in S phase|nuclear cell cycle DNA replication|DNA replication involved in S-phase													biological_process											owl:Class	
GO:0044786	biolink:NamedThing	cell cycle DNA replication	The DNA-dependent DNA replication that takes place as part of the cell cycle.	tmpzr1t_l9r_go_relaxed.owl								jl	2013-05-02T15:52:22Z					biological_process											owl:Class	
GO:0014742	biolink:NamedThing	positive regulation of muscle hypertrophy	Any process that activates or increases the frequency, rate or extent of muscle hypertrophy.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0018181	biolink:NamedThing	peptidyl-arginine C5-methylation	The methylation of peptidyl-arginine on the carbon 5 (C5) residue to form peptidyl-5-methyl-L-arginine.	tmpzr1t_l9r_go_relaxed.owl	peptidyl-arginine 5-methylation				RESID:AA0272									biological_process											owl:Class	
GO:0035245	biolink:NamedThing	peptidyl-arginine C-methylation	The addition of a methyl group onto a carbon atom of an arginine residue in a protein.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0060549	biolink:NamedThing	regulation of fructose 1,6-bisphosphate 1-phosphatase activity	Any process that modulates the rate, frequency or extent of fructose 1,6-bisphosphate 1-phosphatase activity. Fructose 1,6-bisphosphate 1-phosphatase activity is the catalysis of the reaction: D-fructose 1,6-bisphosphate + H2O = D-fructose 6-phosphate + phosphate.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-04-13T02:07:32Z					biological_process											owl:Class	
GO:0032113	biolink:NamedThing	regulation of carbohydrate phosphatase activity	Any process that modulates the frequency, rate or extent of carbohydrate phosphatase activity, the catalysis of the hydrolysis of phosphate from a carbohydrate phosphate.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0031538	biolink:NamedThing	negative regulation of anthocyanin metabolic process	Any process that stops, prevents, or reduces the frequency, rate or extent of chemical reactions and pathways involving anthocyanins.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of anthocyanin metabolic process|inhibition of anthocyanin metabolic process|negative regulation of anthocyanin metabolism|down regulation of anthocyanin metabolic process|downregulation of anthocyanin metabolic process													biological_process											owl:Class	
GO:0009892	biolink:NamedThing	negative regulation of metabolic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of organismal metabolism|negative regulation of multicellular organismal metabolic process|negative regulation of metabolism|down-regulation of metabolic process|down regulation of metabolic process|inhibition of metabolic process|downregulation of metabolic process|inhibition of organismal metabolic process											GO:0044252		biological_process											owl:Class	
GO:0048875	biolink:NamedThing	chemical homeostasis within a tissue	Any process involved in the maintenance of the internal steady state of the amount of a chemical at the level of the tissue.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0001894	biolink:NamedThing	tissue homeostasis	A homeostatic process involved in the maintenance of an internal steady state within a defined tissue of an organism, including control of cellular proliferation and death and control of metabolic function.	tmpzr1t_l9r_go_relaxed.owl	tissue maintenance													biological_process											owl:Class	
GO:0033496	biolink:NamedThing	sinapate metabolic process	The chemical reactions and pathways involving sinapate, (2E)-3-(4-hydroxy-3,5-dimethoxyphenyl)prop-2-enoate.	tmpzr1t_l9r_go_relaxed.owl	sinapate metabolism													biological_process											owl:Class	
GO:0044542	biolink:NamedThing	plasminogen activation in other organism	The chemical reactions and pathways performed by an organism resulting in the processing of inactive plasminogen to active plasmin in another organism.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-03-22T11:40:03Z					biological_process											owl:Class	
GO:0031639	biolink:NamedThing	plasminogen activation	The process in which inactive plasminogen is processed to active plasmin. This process includes cleavage at an internal Arg-Val site to form an N-terminal A-chain and C-terminal B-chain held together by a disulfide bond, and can include further proteolytic cleavage events to remove the preactivation peptide.	tmpzr1t_l9r_go_relaxed.owl	cleavage of plasminogen to plasmin													biological_process											owl:Class	
GO:1902117	biolink:NamedThing	positive regulation of organelle assembly	Any process that activates or increases the frequency, rate or extent of organelle assembly.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of organelle assembly|up regulation of organelle assembly|activation of organelle assembly|upregulation of organelle assembly							pr	2013-05-14T09:43:36Z					biological_process											owl:Class	
GO:1903568	biolink:NamedThing	negative regulation of protein localization to ciliary membrane	Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to ciliary membrane.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of protein localisation in ciliary membrane|negative regulation of protein localisation to ciliary membrane|down-regulation of protein localization to ciliary membrane|down-regulation of protein localization in ciliary membrane|downregulation of protein localisation in ciliary membrane|negative regulation of protein localization in ciliary membrane|downregulation of protein localization to ciliary membrane|down regulation of protein localization to ciliary membrane|down-regulation of protein localisation in ciliary membrane|inhibition of protein localization to ciliary membrane|downregulation of protein localisation to ciliary membrane|down regulation of protein localization in ciliary membrane|down-regulation of protein localisation to ciliary membrane|inhibition of protein localisation in ciliary membrane|down regulation of protein localisation in ciliary membrane|down regulation of protein localisation to ciliary membrane|downregulation of protein localization in ciliary membrane|inhibition of protein localisation to ciliary membrane|inhibition of protein localization in ciliary membrane							krc	2014-10-24T21:32:59Z					biological_process											owl:Class	
GO:1905476	biolink:NamedThing	negative regulation of protein localization to membrane	Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to membrane.	tmpzr1t_l9r_go_relaxed.owl	inhibition of protein localization in membrane|downregulation of protein localization in membrane|downregulation of protein localisation in membrane|negative regulation of protein localization in membrane|down-regulation of protein localisation in membrane|down regulation of protein localization to membrane|negative regulation of protein localisation in membrane|down-regulation of protein localization to membrane|down-regulation of protein localization in membrane|down regulation of protein localization in membrane|inhibition of protein localisation in membrane|downregulation of protein localization to membrane|down regulation of protein localisation in membrane|inhibition of protein localization to membrane							bc	2016-09-21T16:20:10Z					biological_process											owl:Class	
GO:1990686	biolink:NamedThing	LDL-containing protein-lipid-RNA complex	A protein-lipid-RNA complex containing separate low-density lipoprotein (LDL), lipid and RNA molecules. Separate in this context means not covalently bound to each other.	tmpzr1t_l9r_go_relaxed.owl						Examples of LDL-containing protein-lipid-RNA complexes are described in PMID:21423178 and PMID:23559634, both showing evidence that high-density lipoprotein (HDL) and, to a lesser extent, low-density lipoprotein (HDL) transport endogenous microRNAs (miRNAs) and deliver them to recipient cells with functional targeting capabilities. Also see fig. 1 in the review PMID:22028337. Not to be confused with GO:0034362 'low-density lipoprotein particle', which describe complexes of proteins and lipids only, without RNAs.		pr	2015-03-11T15:11:34Z					cellular_component											owl:Class	
GO:1990684	biolink:NamedThing	protein-lipid-RNA complex	A macromolecular complex containing separate protein, lipid and RNA molecules. Separate in this context means not covalently bound to each other.	tmpzr1t_l9r_go_relaxed.owl	miRNA-lipoprotein complex					Examples of protein-lipid-RNA complexes are described in PMID:21423178 and PMID:23559634, both showing evidence that high-density lipoprotein (HDL) and, to a lesser extent, low-density lipoprotein (HDL) transport endogenous microRNAs (miRNAs) and deliver them to recipient cells with functional targeting capabilities. Also see fig. 1 in the review PMID:22028337. Not to be confused with GO:0034364 'high-density lipoprotein particle' or GO:0034362 'low-density lipoprotein particle', which describe complexes of proteins and lipids only, without RNAs.		pr	2015-03-11T14:24:33Z					cellular_component											owl:Class	
GO:0030049	biolink:NamedThing	muscle filament sliding	The sliding of actin thin filaments and myosin thick filaments past each other in muscle contraction. This involves a process of interaction of myosin located on a thick filament with actin located on a thin filament. During this process ATP is split and forces are generated.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0033275	biolink:NamedThing	actin-myosin filament sliding	The sliding movement of actin thin filaments and myosin thick filaments past each other.	tmpzr1t_l9r_go_relaxed.owl	actin filament sliding													biological_process											owl:Class	
GO:1900349	biolink:NamedThing	negative regulation of methane biosynthetic process from methylamine	Any process that stops, prevents or reduces the frequency, rate or extent of methane biosynthetic process from methylamine.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of methane biosynthetic process from methylamine|inhibition of methane biosynthetic process from methylamine|down regulation of methane biosynthetic process from methylamine|downregulation of methane biosynthetic process from methylamine							tt	2012-04-06T02:12:04Z					biological_process											owl:Class	
GO:0051172	biolink:NamedThing	negative regulation of nitrogen compound metabolic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving nitrogen or nitrogenous compounds.	tmpzr1t_l9r_go_relaxed.owl	inhibition of nitrogen metabolic process|negative regulation of nitrogen metabolism|down-regulation of nitrogen metabolic process|down regulation of nitrogen metabolic process|negative regulation of nitrogen metabolic process|downregulation of nitrogen metabolic process													biological_process											owl:Class	
GO:0001737	biolink:NamedThing	establishment of imaginal disc-derived wing hair orientation	Orientation of hairs in the imaginal disc-derived wing along a proximal-distal axis, such that each cell of the wing produces one wing hair which points in a distal direction.	tmpzr1t_l9r_go_relaxed.owl	establishment of wing hair orientation													biological_process											owl:Class	
GO:0045859	biolink:NamedThing	regulation of protein kinase activity	Any process that modulates the frequency, rate or extent of protein kinase activity.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0006882	biolink:NamedThing	cellular zinc ion homeostasis	Any process involved in the maintenance of an internal steady state of zinc ions at the level of a cell.	tmpzr1t_l9r_go_relaxed.owl	zinc homeostasis													biological_process											owl:Class	
GO:0046916	biolink:NamedThing	cellular transition metal ion homeostasis	Any process involved in the maintenance of an internal steady state of transition metal ions at the level of a cell. A transition metal is an element whose atom has an incomplete d-subshell of extranuclear electrons, or which gives rise to a cation or cations with an incomplete d-subshell. Transition metals often have more than one valency state. Biologically relevant transition metals include vanadium, manganese, iron, copper, cobalt, nickel, molybdenum and silver.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0051280	biolink:NamedThing	negative regulation of release of sequestered calcium ion into cytosol	Any process that stops, prevents, or reduces the frequency, rate or extent of the release into the cytosolic compartment of calcium ions sequestered in the endoplasmic reticulum or mitochondria.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of cytosolic release of stored calcium ion (Ca2+)|negative regulation of cytosolic release of sequestered calcium ion (Ca2+)|downregulation of release of sequestered calcium ion into cytosol|inhibition of release of sequestered calcium ion into cytosol|negative regulation of release of stored calcium ion (Ca2+)|negative regulation of cytoplasmic release of sequestered calcium ion (Ca2+)|negative regulation of calcium ion (Ca2+) mobilization|negative regulation of release of stored calcium ion (Ca2+) into cytosol|negative regulation of release of sequestered calcium ion (Ca2+)|negative regulation of calcium mobilization|negative regulation of release of stored calcium ion (Ca2+) into cytoplasm|negative regulation of cytoplasmic release of stored calcium ion (Ca2+)|down-regulation of release of sequestered calcium ion into cytosol|down regulation of release of sequestered calcium ion into cytosol|negative regulation of release of sequestered calcium ion into cytoplasm													biological_process											owl:Class	
GO:0120010	biolink:NamedThing	intermembrane phospholipid transfer	The transport of phospholipids between membranes in which a phospholipid molecule is transported through an aqueous phase from the outer leaflet of a donor membrane to the outer leaflet of an acceptor membrane.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/12329						krc	2017-03-16T20:56:03Z					biological_process											owl:Class	
GO:0120009	biolink:NamedThing	intermembrane lipid transfer	The transport of lipids between membranes in which a lipid molecule is transported through an aqueous phase from the outer leaflet of a donor membrane to the outer leaflet of an acceptor membrane. This process does not require metabolic energy and can be either spontaneous or mediated by lipid transfer proteins (LTPs).	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/12329						krc	2017-03-16T20:30:42Z					biological_process											owl:Class	
GO:1903742	biolink:NamedThing	regulation of anterograde synaptic vesicle transport	Any process that modulates the frequency, rate or extent of anterograde synaptic vesicle transport.	tmpzr1t_l9r_go_relaxed.owl								kmv	2014-12-12T16:28:27Z					biological_process											owl:Class	
GO:1902803	biolink:NamedThing	regulation of synaptic vesicle transport	Any process that modulates the frequency, rate or extent of synaptic vesicle transport.	tmpzr1t_l9r_go_relaxed.owl	regulation of synaptic vesicle fusion|regulation of synaptic vesicle fission							kmv	2014-03-25T14:56:34Z					biological_process											owl:Class	
GO:0035895	biolink:NamedThing	modulation of mast cell degranulation in other organism	Any process in which an organism modulates the frequency, rate or extent of blood mast cell degranulation in another organism. Mast cell degranulation is the regulated exocytosis of secretory granules containing preformed mediators such as histamine, serotonin, and neutral proteases by a mast cell.	tmpzr1t_l9r_go_relaxed.owl	regulation of mast cell degranulation in other organism							bf	2011-06-15T02:46:50Z					biological_process											owl:Class	
GO:0043304	biolink:NamedThing	regulation of mast cell degranulation	Any process that modulates the frequency, rate, or extent of mast cell degranulation.	tmpzr1t_l9r_go_relaxed.owl	regulation of mast cell granule exocytosis													biological_process											owl:Class	
GO:0046809	biolink:NamedThing	replication compartment	Globular nuclear domains where the transcription and replication of the viral genome occurs. More than one site can be present simultaneously.	tmpzr1t_l9r_go_relaxed.owl	RC													cellular_component											owl:Class	
GO:0039715	biolink:NamedThing	nuclear viral factory	A viral factory located in the nucleus of a host cell.	tmpzr1t_l9r_go_relaxed.owl								bf	2013-12-19T15:18:07Z					cellular_component											owl:Class	
GO:0039563	biolink:NamedThing	suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of a JAK-STAT signal cascade in a host organism by reducing the activity of host STAT1 (signal transducer and activator of transcription 1).	tmpzr1t_l9r_go_relaxed.owl	suppression by virus of host STAT1 activity|inhibition by virus of host STAT1 activity|inhibition of host STAT1 by virus	https://github.com/geneontology/go-ontology/issues/21963				This term is for annotation of viral proteins that counteract the host anti-viral innate immune response.		bf	2012-03-12T02:35:39Z					biological_process											owl:Class	
GO:0039562	biolink:NamedThing	suppression by virus of host JAK-STAT cascade via inhibition of STAT activity	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of a JAK-STAT signal cascade in a host organism by reducing the activity of host STAT (signal transducer and activator of transcription). STATs are SH2 domain-containing proteins which lie downstream of many signaling receptors. Upon phosphorylation by JAKs, STAT proteins hetero- or homo-dimerize and translocate to the nucleus to activate transcription of target genes.	tmpzr1t_l9r_go_relaxed.owl	suppression by virus of host signal transducer and activator of transcription activity|inhibition by virus of host STAT activity|suppression by virus of host STAT activity	https://github.com/geneontology/go-ontology/issues/21963				This term is for annotation of viral proteins that counteract the host anti-viral innate immune response.		bf	2012-03-12T02:28:39Z					biological_process											owl:Class	
GO:0048534	biolink:NamedThing	hematopoietic or lymphoid organ development	The process whose specific outcome is the progression of any organ involved in hematopoiesis (also known as hemopoiesis) or lymphoid cell activation over time, from its formation to the mature structure. Such development includes differentiation of resident cell types (stromal cells) and of migratory cell types dependent on the unique microenvironment afforded by the organ for their proper differentiation.	tmpzr1t_l9r_go_relaxed.owl	hemopoietic or lymphoid organ development|haemopoietic or lymphoid organ development|haematopoietic or lymphoid organ development													biological_process											owl:Class	
GO:0006727	biolink:NamedThing	ommochrome biosynthetic process	The chemical reactions and pathways resulting in the formation of ommochromes, any of a large group of natural polycyclic pigments commonly found in the Arthropoda, particularly in the ommatidia of the compound eye.	tmpzr1t_l9r_go_relaxed.owl	ommochrome formation|ommochrome biosynthesis|ommochrome synthesis|ommochrome anabolism													biological_process											owl:Class	
GO:1901667	biolink:NamedThing	negative regulation of skeletal muscle satellite cell activation involved in skeletal muscle regeneration	Any process that stops, prevents or reduces the frequency, rate or extent of satellite cell activation involved in skeletal muscle regeneration.	tmpzr1t_l9r_go_relaxed.owl	down regulation of satellite cell activation involved in skeletal muscle regeneration|downregulation of satellite cell activation involved in skeletal muscle regeneration|inhibition of satellite cell activation involved in skeletal muscle regeneration|down-regulation of satellite cell activation involved in skeletal muscle regeneration							dph	2012-11-21T16:21:11Z					biological_process											owl:Class	
GO:0043417	biolink:NamedThing	negative regulation of skeletal muscle tissue regeneration	Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle regeneration.	tmpzr1t_l9r_go_relaxed.owl	down regulation of skeletal muscle regeneration|down-regulation of skeletal muscle regeneration|inhibition of skeletal muscle regeneration|downregulation of skeletal muscle regeneration													biological_process											owl:Class	
GO:0042246	biolink:NamedThing	tissue regeneration	The regrowth of lost or destroyed tissues.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0048589	biolink:NamedThing	developmental growth	The increase in size or mass of an entire organism, a part of an organism or a cell, where the increase in size or mass has the specific outcome of the progression of the organism over time from one condition to another.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0044361	biolink:NamedThing	negative regulation of voltage-gated potassium channel activity in other organism	Any process in which an organism stops, prevents or reduces the frequency, rate or extent of the activity of a voltage-gated potassium channel in another organism.	tmpzr1t_l9r_go_relaxed.owl								jl	2011-10-27T02:11:52Z					biological_process											owl:Class	
GO:0044360	biolink:NamedThing	modulation of voltage-gated potassium channel activity in other organism	Any process in which an organism effects a change in the frequency, rate or extent of the activity of a voltage-gated potassium channel in another organism.	tmpzr1t_l9r_go_relaxed.owl								jl	2011-10-27T02:09:28Z					biological_process											owl:Class	
GO:1900617	biolink:NamedThing	emericellamide A biosynthetic process	The chemical reactions and pathways resulting in the formation of emericellamide A.	tmpzr1t_l9r_go_relaxed.owl	emericellamide A anabolism|emericellamide A synthesis|emericellamide A formation|emericellamide A biosynthesis							di	2012-05-15T08:00:27Z					biological_process											owl:Class	
GO:1900615	biolink:NamedThing	emericellamide A metabolic process	The chemical reactions and pathways involving emericellamide A.	tmpzr1t_l9r_go_relaxed.owl	emericellamide A metabolism							di	2012-05-15T07:59:59Z					biological_process											owl:Class	
GO:1901078	biolink:NamedThing	negative regulation of relaxation of muscle	Any process that stops, prevents or reduces the frequency, rate or extent of relaxation of muscle.	tmpzr1t_l9r_go_relaxed.owl	downregulation of relaxation of muscle|down-regulation of relaxation of muscle|inhibition of relaxation of muscle|down regulation of relaxation of muscle							jl	2012-07-04T10:44:54Z					biological_process											owl:Class	
GO:1901077	biolink:NamedThing	regulation of relaxation of muscle	Any process that modulates the frequency, rate or extent of relaxation of muscle.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-07-04T10:44:30Z					biological_process											owl:Class	
GO:1903551	biolink:NamedThing	regulation of extracellular exosome assembly	Any process that modulates the frequency, rate or extent of extracellular vesicular exosome assembly.	tmpzr1t_l9r_go_relaxed.owl	regulation of extracellular vesicular exosome assembly							pga	2014-10-20T15:37:25Z					biological_process											owl:Class	
GO:0099565	biolink:NamedThing	chemical synaptic transmission, postsynaptic	The part of synaptic transmission occurring in the post-synapse: a signal transduction pathway consisting of neurotransmitter receptor activation and its effects on postsynaptic membrane potential and the ionic composition of the postsynaptic cytosol.	tmpzr1t_l9r_go_relaxed.owl	postsynaptic process involved in chemical synaptic transmission													biological_process											owl:Class	
GO:0007166	biolink:NamedThing	cell surface receptor signaling pathway	A series of molecular signals initiated by activation of a receptor on the surface of a cell. The pathway begins with binding of an extracellular ligand to a cell surface receptor, or for receptors that signal in the absence of a ligand, by ligand-withdrawal or the activity of a constitutively active receptor. The pathway ends with regulation of a downstream cellular process, e.g. transcription.	tmpzr1t_l9r_go_relaxed.owl	cell surface receptor linked signaling pathway|cell surface receptor linked signalling pathway|cell surface receptor linked signal transduction													biological_process											owl:Class	
GO:0007533	biolink:NamedThing	mating type switching	The conversion of a single-cell organism from one mating type to another by the precise replacement of a DNA sequence at the expressed mating type locus with a copy of a sequence from a donor locus.	tmpzr1t_l9r_go_relaxed.owl	mating type switching and recombination													biological_process											owl:Class	
GO:0007531	biolink:NamedThing	mating type determination	Any process that establishes and transmits the specification of mating type upon an individual. Mating types are the equivalent in microorganisms of the sexes in higher organisms.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0070874	biolink:NamedThing	negative regulation of glycogen metabolic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving glycogen.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of glycogen metabolism							mah	2009-08-20T02:50:41Z					biological_process											owl:Class	
GO:0032497	biolink:NamedThing	detection of lipopolysaccharide	The series of events in which a lipopolysaccharide stimulus is received by a cell and converted into a molecular signal. Lipopolysaccharide is a major component of the cell wall of gram-negative bacteria.	tmpzr1t_l9r_go_relaxed.owl	detection of LPS													biological_process											owl:Class	
GO:0032496	biolink:NamedThing	response to lipopolysaccharide	Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipopolysaccharide stimulus; lipopolysaccharide is a major component of the cell wall of gram-negative bacteria.	tmpzr1t_l9r_go_relaxed.owl	response to endotoxin|response to LPS													biological_process											owl:Class	
GO:0051477	biolink:NamedThing	mannosylglycerate transmembrane transporter activity	Enables the transfer of a mannosylglycerate from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0046943	biolink:NamedThing	carboxylic acid transmembrane transporter activity	Enables the transfer of carboxylic acids from one side of a membrane to the other. Carboxylic acids are organic acids containing one or more carboxyl (COOH) groups or anions (COO-).	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-390347									molecular_function											owl:Class	
GO:1905609	biolink:NamedThing	positive regulation of smooth muscle cell-matrix adhesion	Any process that activates or increases the frequency, rate or extent of smooth muscle cell-matrix adhesion.	tmpzr1t_l9r_go_relaxed.owl	up regulation of smooth muscle cell-matrix adhesion|upregulation of smooth muscle cell-matrix adhesion|up-regulation of smooth muscle cell-matrix adhesion|activation of smooth muscle cell-matrix adhesion							sl	2016-10-27T21:58:11Z					biological_process											owl:Class	
GO:0001954	biolink:NamedThing	positive regulation of cell-matrix adhesion	Any process that activates or increases the rate or extent of cell adhesion to an extracellular matrix.	tmpzr1t_l9r_go_relaxed.owl	stimulation of cell-matrix adhesion|activation of cell-matrix adhesion|up regulation of cell-matrix adhesion|upregulation of cell-matrix adhesion|up-regulation of cell-matrix adhesion													biological_process											owl:Class	
GO:0045162	biolink:NamedThing	clustering of voltage-gated sodium channels	The process in which voltage-gated sodium channels become localized together in high densities. In animals, nodes of Ranvier differ dramatically from internodal axonal regions in very high densities of voltage-dependent sodium (Nav) channels responsible for the rapid, inward ionic currents that produce membrane depolarization.	tmpzr1t_l9r_go_relaxed.owl	Nav channel clustering|clustering of voltage-dependent sodium channels|clustering of voltage gated sodium channels|voltage-gated sodium channel clustering													biological_process											owl:Class	
GO:0045161	biolink:NamedThing	neuronal ion channel clustering	The process in which voltage-gated ion channels become localized to distinct subcellular domains in the neuron. Specific targeting, clustering, and maintenance of these channels in their respective domains are essential to achieve high conduction velocities of action potential propagation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0097140	biolink:NamedThing	BIM-BCL-xl complex	A heterodimeric protein complex consisting of BIM and BCL-xl, members of the Bcl-2 family of anti- and proapoptotic regulators.	tmpzr1t_l9r_go_relaxed.owl								pr	2011-08-02T01:41:30Z					cellular_component											owl:Class	
GO:0097136	biolink:NamedThing	Bcl-2 family protein complex	A protein complex that consists of members of the Bcl-2 family of anti- and proapoptotic regulators. Bcl-2 proteins respond to cues from various forms of intracellular stress, such as DNA damage or cytokine deprivation, and interact with opposing family members to determine whether or not the caspase proteolytic cascade should be unleashed.	tmpzr1t_l9r_go_relaxed.owl								pr	2011-08-02T01:34:19Z					cellular_component											owl:Class	
GO:1903388	biolink:NamedThing	regulation of synaptic vesicle uncoating	Any process that modulates the frequency, rate or extent of synaptic vesicle uncoating.	tmpzr1t_l9r_go_relaxed.owl	regulation of synaptic vesicle coat depolymerization|regulation of synaptic vesicle coat protein depolymerization							pad	2014-08-27T10:02:53Z					biological_process											owl:Class	
GO:1901879	biolink:NamedThing	regulation of protein depolymerization	Any process that modulates the frequency, rate or extent of protein depolymerization.	tmpzr1t_l9r_go_relaxed.owl	regulation of protein polymer catabolic process|regulation of protein polymer breakdown|regulation of protein polymer degradation|regulation of protein polymer catabolism							rl	2013-02-06T13:57:23Z					biological_process											owl:Class	
GO:0000827	biolink:NamedThing	inositol-1,3,4,5,6-pentakisphosphate kinase activity	Catalysis of the reaction: ATP + 1D-myo-inositol 1,3,4,5,6-pentakisphosphate = ADP + diphospho-1D-myo-inositol tetrakisphosphate. The isomeric configuration of diphospho-1D-myo-inositol tetrakisphosphate is unknown.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-1855223|Reactome:R-HSA-1855181|EC:2.7.4.21									molecular_function											owl:Class	
GO:0016776	biolink:NamedThing	phosphotransferase activity, phosphate group as acceptor	Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to a phosphate group (acceptor).	tmpzr1t_l9r_go_relaxed.owl					EC:2.7.4.-									molecular_function											owl:Class	
GO:0102046	biolink:NamedThing	3,4-dichlorobenzoate-4,5-oxygenase activity	Catalysis of the reaction: 3,4-dichlorobenzoate + O2 + a reduced electron acceptor <=> 3,4-dichlorobenzoate-cis-4,5-diol + an oxidized electron acceptor.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-10427									molecular_function											owl:Class	
GO:0016708	biolink:NamedThing	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor	Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from NADH or NADPH and one other donor, and two atoms of oxygen are incorporated into one donor.	tmpzr1t_l9r_go_relaxed.owl	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of two atoms of oxygen into one donor				EC:1.14.12.-									molecular_function											owl:Class	
GO:1901874	biolink:NamedThing	negative regulation of post-translational protein modification	Any process that stops, prevents or reduces the frequency, rate or extent of post-translational protein modification.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of posttranslational protein modification|downregulation of post-translational amino acid modification|down regulation of posttranslational amino acid modification|inhibition of posttranslational amino acid modification|down regulation of post-translational protein modification|inhibition of posttranslational protein modification|downregulation of posttranslational protein modification|down-regulation of posttranslational amino acid modification|negative regulation of PTM|negative regulation of posttranslational amino acid modification|down regulation of post-translational modification|negative regulation of post-translational modification|inhibition of post-translational amino acid modification|downregulation of posttranslational amino acid modification|inhibition of posttranslational modification|downregulation of posttranslational modification|negative regulation of posttranslational protein modification|down-regulation of PTM|down regulation of posttranslational protein modification|negative regulation of post-translational amino acid modification|inhibition of post-translational modification|down regulation of posttranslational modification|down regulation of PTM|down-regulation of posttranslational modification|inhibition of post-translational protein modification|downregulation of PTM|downregulation of post-translational modification|inhibition of PTM|down-regulation of post-translational amino acid modification|down regulation of post-translational amino acid modification|downregulation of post-translational protein modification|down-regulation of post-translational protein modification|negative regulation of posttranslational modification|down-regulation of post-translational modification							yaf	2013-02-05T10:02:57Z					biological_process											owl:Class	
GO:1901873	biolink:NamedThing	regulation of post-translational protein modification	Any process that modulates the frequency, rate or extent of post-translational protein modification.	tmpzr1t_l9r_go_relaxed.owl	regulation of post-translational modification|regulation of PTM|regulation of posttranslational protein modification|regulation of posttranslational modification|regulation of posttranslational amino acid modification|regulation of post-translational amino acid modification							yaf	2013-02-05T10:02:52Z					biological_process											owl:Class	
GO:0061133	biolink:NamedThing	endopeptidase activator activity	Binds to and increases the activity of an endopeptidase, any enzyme that hydrolyzes nonterminal peptide bonds in polypeptides.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-05-17T01:08:29Z					molecular_function											owl:Class	
GO:0010906	biolink:NamedThing	regulation of glucose metabolic process	Any process that modulates the rate, frequency or extent of glucose metabolism. Glucose metabolic processes are the chemical reactions and pathways involving glucose, the aldohexose gluco-hexose.	tmpzr1t_l9r_go_relaxed.owl	regulation of glucose metabolism													biological_process											owl:Class	
GO:1901156	biolink:NamedThing	neomycin metabolic process	The chemical reactions and pathways involving neomycin.	tmpzr1t_l9r_go_relaxed.owl	neomycin metabolism							yaf	2012-07-17T04:27:57Z					biological_process											owl:Class	
GO:2001209	biolink:NamedThing	positive regulation of transcription elongation from RNA polymerase I promoter	Any process that activates or increases the frequency, rate or extent of transcription elongation from RNA polymerase I promoter.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of RNA elongation from Pol I promoter							se	2011-11-11T10:46:41Z					biological_process											owl:Class	
GO:0032786	biolink:NamedThing	positive regulation of DNA-templated transcription, elongation	Any process that activates or increases the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides catalyzed by a DNA-dependent RNA polymerase.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of RNA elongation|stimulation of RNA elongation|activation of RNA elongation|positive regulation of transcriptional elongation|positive regulation of DNA-dependent transcription, elongation|positive regulation of transcription elongation|up regulation of RNA elongation|positive regulation of transcription elongation, DNA-dependent|upregulation of RNA elongation|positive transcription elongation regulator activity													biological_process											owl:Class	
GO:0102674	biolink:NamedThing	C4-demethylase activity	Catalysis of the reaction: 24-methylenelophenol + a demethylated methyl acceptor <=> 9xi-episterol + a methylated methyl acceptor.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-4181									molecular_function											owl:Class	
GO:1901686	biolink:NamedThing	glutathione derivative catabolic process	The chemical reactions and pathways resulting in the breakdown of glutathione derivative.	tmpzr1t_l9r_go_relaxed.owl	glutathione derivative degradation|glutathione derivative catabolism|glutathione derivative breakdown							pr	2012-12-05T11:57:16Z					biological_process											owl:Class	
GO:0044273	biolink:NamedThing	sulfur compound catabolic process	The chemical reactions and pathways resulting in the breakdown of compounds that contain sulfur, such as the amino acids methionine and cysteine or the tripeptide glutathione.	tmpzr1t_l9r_go_relaxed.owl	sulfur compound breakdown|sulfur catabolism|sulfur compound catabolism|sulfur catabolic process|sulfur compound degradation													biological_process											owl:Class	
GO:0075249	biolink:NamedThing	positive regulation of aeciospore formation	Any process that activates, maintains or increases the frequency, rate or extent of aeciospore formation, a process in which a dikaryotic spore of typically a rust fungus is produced in an aecium.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0075248	biolink:NamedThing	regulation of aeciospore formation	Any process that modulates the frequency, rate or extent of aeciospore formation, a process in which a dikaryotic spore of typically a rust fungus is produced in an aecium.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0097218	biolink:NamedThing	sieve plate	A part of the cell wall of a sieve tube member that bears one or more highly specialized sieve areas.	tmpzr1t_l9r_go_relaxed.owl						Typical of angiosperms. Part of sieve tube member (PO:0000289).		pr	2012-01-13T05:42:48Z					cellular_component											owl:Class	
GO:1990571	biolink:NamedThing	meiotic centromere clustering	The process by which centromeres/kinetochores attach to and migrate along microtubules to become localized to clusters at the spindle pole body during a meiotic prometaphase I.	tmpzr1t_l9r_go_relaxed.owl	homologous chromosome movement towards spindle pole in meiosis I prometaphase|centromere clustering during meiosis							mah	2014-12-02T11:25:37Z					biological_process											owl:Class	
GO:0016344	biolink:NamedThing	meiotic chromosome movement towards spindle pole	The cell cycle process in which the directed movement of chromosomes from the center of the spindle towards the spindle poles takes place, mediated by the shortening of microtubules attached to the chromosomes. This occurs during meiosis.	tmpzr1t_l9r_go_relaxed.owl	meiotic chromosome movement|chromosome migration to spindle pole during meiosis|chromosome movement towards spindle pole during meiosis|meiotic chromosome movement to spindle pole													biological_process											owl:Class	
GO:0043911	biolink:NamedThing	D-lysine transaminase activity	Catalysis of the reaction: D-lysine + 2-oxoglutarate = L-glutamate + 6-amino-2-oxohexanoate.	tmpzr1t_l9r_go_relaxed.owl	D-lysine aminotransferase activity													molecular_function											owl:Class	
GO:0008483	biolink:NamedThing	transaminase activity	Catalysis of the transfer of an amino group to an acceptor, usually a 2-oxo acid.	tmpzr1t_l9r_go_relaxed.owl	aminotransferase activity				Reactome:R-HSA-1237102|EC:2.6.1.-									molecular_function											owl:Class	
GO:0036495	biolink:NamedThing	negative regulation of translation initiation in response to endoplasmic reticulum stress	Any process that stops, prevents, or reduces the frequency, rate or extent of translation initiation as a result of endoplasmic reticulum stress.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of translation initiation in response to ER stress							bf	2015-02-05T10:13:38Z					biological_process											owl:Class	
GO:0060311	biolink:NamedThing	negative regulation of elastin catabolic process	Any process that decreases the rate, frequency or extent of elastin catabolism, the chemical reactions and pathways resulting in the breakdown of elastin.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of elastin catabolic process|negative regulation of elastin degradation|negative regulation of elastin catabolism|negative regulation of elastin breakdown													biological_process											owl:Class	
GO:1903019	biolink:NamedThing	negative regulation of glycoprotein metabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of glycoprotein metabolic process.	tmpzr1t_l9r_go_relaxed.owl	down regulation of glycoprotein metabolic process|down-regulation of glycoprotein metabolism|inhibition of glycoprotein metabolic process|down regulation of glycoprotein metabolism|down-regulation of glycoprotein metabolic process|inhibition of glycoprotein metabolism|downregulation of glycoprotein metabolism|downregulation of glycoprotein metabolic process|negative regulation of glycoprotein metabolism					human serum amyloid P component (SAP) P02743 inhibits viral neuraminidase, NA (exo-alpha-sialidase activity) and thus the metabolism of glycoproteins, demonstrated in Figure 4A PMID:23544079, (IDA), the negative regulation term would be applied to this protein		rl	2014-05-14T18:44:25Z					biological_process											owl:Class	
GO:1904324	biolink:NamedThing	negative regulation of inhibitory G protein-coupled receptor phosphorylation	Any process that stops, prevents or reduces the frequency, rate or extent of inhibitory G protein-coupled receptor phosphorylation.	tmpzr1t_l9r_go_relaxed.owl	inhibition of inhibitory G-protein coupled receptor phosphorylation|downregulation of inhibitory G-protein coupled receptor phosphorylation|down-regulation of inhibitory G-protein coupled receptor phosphorylation|negative regulation of inhibitory G-protein coupled receptor phosphorylation|down regulation of inhibitory G-protein coupled receptor phosphorylation							sl	2015-06-10T19:46:43Z					biological_process											owl:Class	
GO:0020013	biolink:NamedThing	modulation by symbiont of host erythrocyte aggregation	Any process in which a symbiont organism modulates the frequency, rate or extent of erythrocyte aggregation in its host organism, e.g. the binding of parasite-infected erythrocytes to uninfected erythrocytes.	tmpzr1t_l9r_go_relaxed.owl	rosetting				Wikipedia:Rosetting	Please note that this term does not refer to the in vitro assay called erythrocyte rosetting.								biological_process											owl:Class	
GO:0045224	biolink:NamedThing	positive regulation of CD4 production	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of CD4.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of CD4 anabolism|positive regulation of CD4 formation|activation of CD4 biosynthetic process|upregulation of CD4 biosynthetic process|positive regulation of CD4 biosynthesis|positive regulation of CD4 biosynthetic process|stimulation of CD4 biosynthetic process|up-regulation of CD4 biosynthetic process|up regulation of CD4 biosynthetic process|positive regulation of CD4 synthesis													biological_process											owl:Class	
GO:0045223	biolink:NamedThing	regulation of CD4 production	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of CD4.	tmpzr1t_l9r_go_relaxed.owl	regulation of CD4 biosynthesis|regulation of CD4 synthesis|regulation of CD4 formation|regulation of CD4 anabolism|regulation of CD4 biosynthetic process													biological_process											owl:Class	
GO:0050578	biolink:NamedThing	(R)-2-hydroxyacid dehydrogenase activity	Catalysis of the reaction: (S)-3-sulfolactate + NAD(P)+ = 3-sulfopyruvate + NAD(P)H + H+.	tmpzr1t_l9r_go_relaxed.owl	(R)-sulfolactate:NAD(P)+ oxidoreductase activity|(R)-2-hydroxyacid:NAD(P)+ oxidoreductase activity|L-sulfolactate dehydrogenase activity|(R)-sulfolactate:NAD(P)(+) oxidoreductase activity				RHEA:35735|EC:1.1.1.272|MetaCyc:1.1.1.272-RXN									molecular_function											owl:Class	
GO:1902448	biolink:NamedThing	positive regulation of shade avoidance	Any process that activates or increases the frequency, rate or extent of shade avoidance.	tmpzr1t_l9r_go_relaxed.owl	upregulation of shade avoidance|activation of shade avoidance|up regulation of shade avoidance|up-regulation of shade avoidance							dhl	2013-10-15T21:05:00Z					biological_process											owl:Class	
GO:0047127	biolink:NamedThing	thiomorpholine-carboxylate dehydrogenase activity	Catalysis of the reaction: NAD(P)+ + thiomorpholine-3-carboxylate = NAD(P)H + 3,4-dehydro-1,4-thiomorpholine-3-carboxylate.	tmpzr1t_l9r_go_relaxed.owl	ketimine reductase activity|thiomorpholine-3-carboxylate:NAD(P)+ 5,6-oxidoreductase activity|ketimine-reducing enzyme				Reactome:R-HSA-5693347|MetaCyc:1.5.1.25-RXN|EC:1.5.1.25									molecular_function											owl:Class	
GO:0015112	biolink:NamedThing	nitrate transmembrane transporter activity	Enables the transfer of nitrate ions (NO3-) from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	nitrite/nitrate porter activity	https://github.com/geneontology/go-ontology/issues/21337			RHEA:34923									molecular_function											owl:Class	
GO:0015103	biolink:NamedThing	inorganic anion transmembrane transporter activity	Enables the transfer of inorganic anions from one side of a membrane to the other. Inorganic anions are atoms or small molecules with a negative charge which do not contain carbon in covalent linkage.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0097192	biolink:NamedThing	extrinsic apoptotic signaling pathway in absence of ligand	A series of molecular signals in which a signal is conveyed from the cell surface to trigger the apoptotic death of a cell. The pathway starts with withdrawal of a ligand from a cell surface receptor, and ends when the execution phase of apoptosis is triggered.	tmpzr1t_l9r_go_relaxed.owl	dependence receptor signaling pathway|extrinsic apoptosis in absence of ligand|extrinsic apoptotic signalling pathway in absence of ligand					For dependence receptors, absence of a ligand or withdrawal of a ligand from a receptor acts as a signal. An example of 'extrinsic apoptotic signaling pathway in absence of ligand' is withdrawal of a growth factor such as NGF, even if traditionally apoptosis induced via growth factor withdrawal has been classified as an instance of intrinsic apoptosis. See an example in PMID:19767770. Ligands whose withdrawal or absence induce apoptosis should be annotated to GO:2001239 'regulation of extrinsic apoptotic signaling pathway in absence of ligand', rather than to the pathway term itself. Examples of gene products that may be annotated to GO:0097192 'extrinsic apoptotic signaling pathway in absence of ligand' include dependence receptors such as DCC or UNC5B, which relay lethal signals in the absence of their ligand (netrin-1). In the case of DCC and UNC5B, the signaling proceeds through the assembly of a DRAL- and TUCAN- (or NLRP1-) containing caspase-9-activating complex or by the dephosphorylation-mediated activation of death-associated protein kinase 1 (DAPK1) by UNC5B-bound protein phosphatase 2A (PP2A), respectively. DAPK1 can mediate the direct activation of executioner caspases or favor MOMP (reviewed in PMID:21760595). Also see PMID:21172653 (annotations to UNC5B and PR65beta, UniProt symbols O08722, PPP2R1B and P30154).		pr	2011-11-23T09:37:09Z					biological_process											owl:Class	
GO:0038034	biolink:NamedThing	signal transduction in absence of ligand	A series of molecular signals initiated by the absence of a ligand or the withdrawal of a ligand from a receptor.	tmpzr1t_l9r_go_relaxed.owl	signal transduction in absence of agonist|basal signaling|negative signal transduction|non-classical signal transduction|dependence receptor signaling pathway|addiction receptor signaling pathway							bf	2011-10-26T02:21:03Z					biological_process											owl:Class	
GO:0015230	biolink:NamedThing	FAD transmembrane transporter activity	Enables the directed movement of flavin-adenine dinucleotide (FAD) from one side of a membrane to the other. FAD forms the coenzyme of the prosthetic group of various flavoprotein oxidoreductase enzymes, in which it functions as an electron acceptor by being reversibly converted to its reduced form.	tmpzr1t_l9r_go_relaxed.owl	flavin-adenine dinucleotide carrier activity|flavin adenine dinucleotide carrier activity|flavin-adenine dinucleotide transmembrane transporter activity|FAD transporter activity|FAD carrier activity|flavin adenine dinucleotide transmembrane transporter activity											GO:0005472		molecular_function											owl:Class	
GO:0015215	biolink:NamedThing	nucleotide transmembrane transporter activity	Enables the transfer of a nucleotide, any compound consisting of a nucleoside that is esterified with (ortho)phosphate, from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0009994	biolink:NamedThing	oocyte differentiation	The process in which a relatively unspecialized immature germ cell acquires the specialized features of a mature female gamete.	tmpzr1t_l9r_go_relaxed.owl	oocyte cell differentiation													biological_process											owl:Class	
GO:0022412	biolink:NamedThing	cellular process involved in reproduction in multicellular organism	A process, occurring at the cellular level, that is involved in the reproductive function of a multicellular organism.	tmpzr1t_l9r_go_relaxed.owl	reproductive cellular process in multicellular organism													biological_process											owl:Class	
GO:0061245	biolink:NamedThing	establishment or maintenance of bipolar cell polarity	Any cellular process that results in the specification, formation or maintenance of a bipolar intracellular organization or cell growth patterns.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-08-23T09:42:05Z					biological_process											owl:Class	
GO:0007163	biolink:NamedThing	establishment or maintenance of cell polarity	Any cellular process that results in the specification, formation or maintenance of anisotropic intracellular organization or cell growth patterns.	tmpzr1t_l9r_go_relaxed.owl	establishment and/or maintenance of cell polarity|establishment and/or maintenance of cell polarization|cell polarity											GO:0030012|GO:0030467		biological_process											owl:Class	
GO:0071010	biolink:NamedThing	prespliceosome	A spliceosomal complex that is formed by association of the 5' splice site and the branch point sequence with specific snRNPs. The prespliceosome includes many proteins in addition to those found in the bound snRNPs. Commitment to a given pair of 5' and 3' splice sites occurs at the time of prespliceosome formation. Prespliceosome complexes are not active for splicing, but are instead an early step in the assembly of a spliceosomal complex.	tmpzr1t_l9r_go_relaxed.owl	yeast spliceosomal complex B|prespliceosomal complex|mammalian spliceosomal complex A							mah	2009-07-30T12:00:35Z					cellular_component											owl:Class	
GO:0005681	biolink:NamedThing	spliceosomal complex	Any of a series of ribonucleoprotein complexes that contain snRNA(s) and small nuclear ribonucleoproteins (snRNPs), and are formed sequentially during the spliceosomal splicing of one or more substrate RNAs, and which also contain the RNA substrate(s) from the initial target RNAs of splicing, the splicing intermediate RNA(s), to the final RNA products. During cis-splicing, the initial target RNA is a single, contiguous RNA transcript, whether mRNA, snoRNA, etc., and the released products are a spliced RNA and an excised intron, generally as a lariat structure. During trans-splicing, there are two initial substrate RNAs, the spliced leader RNA and a pre-mRNA.	tmpzr1t_l9r_go_relaxed.owl	spliceosome complex|spliceosome				Wikipedia:Spliceosome									cellular_component											owl:Class	
GO:0140673	biolink:NamedThing	co-transcriptional chromatin reassembly	The reestablishment of chromatin structure that was disrupted upon passage of RNA polymerase II during transcription elongation. This process prevents cryptic intragenic transcription initiation.	tmpzr1t_l9r_go_relaxed.owl	maintenance of transcriptionally active chromatin during transcription elongation|euchromatin maintenance during transcription elongation|maintainance of chromatin integrity during transcription elongation by RNAPII|chromatin maintenance during transcription elongation	https://github.com/geneontology/go-ontology/issues/21730				Note: Do not confuse with 'GO:0045815 epigenetic maintenance of chromatin in transcription-competent conformation', which describes the maintenance of chromatin in an open conformation (indeendent of transcription).		pg	2021-06-29T09:18:46Z					biological_process											owl:Class	
GO:0031497	biolink:NamedThing	chromatin assembly	The assembly of DNA, histone proteins, other associated proteins, and sometimes RNA, into chromatin structure, beginning with the formation of the basic unit, the nucleosome, followed by organization of the nucleosomes into higher order structures, ultimately giving rise to a complex organization of specific domains within the nucleus.	tmpzr1t_l9r_go_relaxed.owl	chromatin maintenance|establishment of chromatin architecture													biological_process											owl:Class	
GO:0019694	biolink:NamedThing	alkanesulfonate metabolic process	The chemical reactions and pathways involving alkanesulfonates, the anion of alkanesulfonic acids, sulfonic acid derivatives containing an aliphatic hydrocarbon group.	tmpzr1t_l9r_go_relaxed.owl	alkanesulphonate metabolic process|alkanesulphonate metabolism|alkanesulfonate metabolism				MetaCyc:ALKANEMONOX-PWY									biological_process											owl:Class	
GO:0031244	biolink:NamedThing	extrinsic component of cell outer membrane	The component of the cell outer membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.	tmpzr1t_l9r_go_relaxed.owl	extrinsic to cell outer membrane													cellular_component											owl:Class	
GO:2000418	biolink:NamedThing	positive regulation of eosinophil migration	Any process that activates or increases the frequency, rate or extent of eosinophil migration.	tmpzr1t_l9r_go_relaxed.owl								mah	2011-02-23T01:44:14Z					biological_process											owl:Class	
GO:0002687	biolink:NamedThing	positive regulation of leukocyte migration	Any process that activates or increases the frequency, rate, or extent of leukocyte migration.	tmpzr1t_l9r_go_relaxed.owl	activation of leukocyte migration|up regulation of leukocyte migration|positive regulation of immune cell migration|upregulation of leukocyte migration|positive regulation of leucocyte migration|stimulation of leukocyte migration|up-regulation of leukocyte migration													biological_process											owl:Class	
GO:0045268	biolink:NamedThing	plasma membrane proton-transporting ATP synthase, catalytic core	The hexamer that possesses the catalytic activity of the plasma membrane hydrogen-transporting ATP synthase. Examples of this component are found in Bacterial species.	tmpzr1t_l9r_go_relaxed.owl	hydrogen-transporting ATP synthase, catalytic core|proton-transporting ATP synthase, catalytic core													cellular_component											owl:Class	
GO:0045267	biolink:NamedThing	proton-transporting ATP synthase, catalytic core	The hexamer that possesses the catalytic activity of the mitochondrial hydrogen-transporting ATP synthase.	tmpzr1t_l9r_go_relaxed.owl	hydrogen-transporting ATP synthase, catalytic core													cellular_component											owl:Class	
GO:0050457	biolink:NamedThing	decylcitrate synthase activity	Catalysis of the reaction: H(2)O + lauroyl-CoA + oxaloacetate = (2S,3S)-2-hydroxytridecane-1,2,3-tricarboxylate + CoA + H(+).	tmpzr1t_l9r_go_relaxed.owl	(2S,3S)-2-hydroxytridecane-1,2,3-tricarboxylate oxaloacetate-lyase (CoA-acylating)|(2S,3S)-2-hydroxytridecane-1,2,3-tricarboxylate oxaloacetate-lyase (CoA- acylating) activity|2-decylcitrate synthase activity|dodecanoyl-CoA:oxaloacetate C-dodecanoyltransferase (thioester-hydrolysing, 1-carboxyundecyl-forming)				MetaCyc:DECYLCITRATE-SYNTHASE-RXN|KEGG_REACTION:R03735|RHEA:16605|EC:2.3.3.2									molecular_function											owl:Class	
GO:0036008	biolink:NamedThing	sucrose catabolic process to fructose-6-phosphate and glucose-6-phosphate	The chemical reactions and pathways resulting in the breakdown of sucrose, which proceeds by phosphorylation of sucrose to form sucrose-6-phosphate. The subsequent actions of a hydrolase and a fructokinase generate fructose-6-phosphate and glucose-6-phosphate.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:SUCUTIL-PWY			bf	2011-09-23T10:34:08Z					biological_process											owl:Class	
GO:0005987	biolink:NamedThing	sucrose catabolic process	The chemical reactions and pathways resulting in the breakdown of sucrose, the disaccharide fructofuranosyl-glucopyranoside.	tmpzr1t_l9r_go_relaxed.owl	sucrose degradation|sucrose catabolism|sucrose breakdown													biological_process											owl:Class	
GO:0045775	biolink:NamedThing	positive regulation of beta 2 integrin biosynthetic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of beta 2 integrins.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of beta 2 integrin biosynthesis|positive regulation of beta 2 integrin anabolism|positive regulation of beta 2 integrin formation|positive regulation of beta 2 integrin synthesis|upregulation of beta 2 integrin biosynthetic process|activation of beta 2 integrin biosynthetic process|stimulation of beta 2 integrin biosynthetic process|up-regulation of beta 2 integrin biosynthetic process|up regulation of beta 2 integrin biosynthetic process													biological_process											owl:Class	
GO:0061113	biolink:NamedThing	pancreas morphogenesis	Morphogenesis of the pancreas. Morphogenesis is the process in which anatomical structures are generated and organized.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-05-05T11:55:30Z					biological_process											owl:Class	
GO:0007454	biolink:NamedThing	labial disc morphogenesis	The process in which the anatomical structures derived from the labial disc are generated and organized. This includes the transformation of a labial imaginal disc from a monolayered epithelium in the larvae of holometabolous insects into recognizable adult structures including parts of the proboscis.	tmpzr1t_l9r_go_relaxed.owl	labial disc metamorphosis													biological_process											owl:Class	
GO:0007560	biolink:NamedThing	imaginal disc morphogenesis	The process in which the anatomical structures derived from an imaginal disc are generated and organized. The imaginal discs are epithelial infoldings in the larvae of holometabolous insects that develop into adult appendages (legs, antennae, wings, etc.) during metamorphosis from larval to adult form.	tmpzr1t_l9r_go_relaxed.owl	imaginal disc metamorphosis											GO:0007452		biological_process											owl:Class	
GO:1904636	biolink:NamedThing	response to ionomycin	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ionomycin stimulus.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-08-31T14:39:18Z					biological_process											owl:Class	
GO:0070542	biolink:NamedThing	response to fatty acid	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fatty acid stimulus.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:2000013	biolink:NamedThing	regulation of arginine biosynthetic process via ornithine	Any process that modulates the frequency, rate or extent of arginine biosynthetic process via ornithine.	tmpzr1t_l9r_go_relaxed.owl	regulation of arginine formation via ornithine|regulation of arginine anabolism via ornithine|regulation of arginine synthesis via ornithine							tb	2010-08-05T11:21:51Z					biological_process											owl:Class	
GO:1900079	biolink:NamedThing	regulation of arginine biosynthetic process	Any process that modulates the frequency, rate or extent of arginine biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of arginine anabolism|regulation of arginine biosynthesis|regulation of arginine synthesis|regulation of arginine formation							pr	2012-02-01T03:57:36Z					biological_process											owl:Class	
GO:1902037	biolink:NamedThing	negative regulation of hematopoietic stem cell differentiation	Any process that stops, prevents or reduces the frequency, rate or extent of hematopoietic stem cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	inhibition of haematopoietic stem cell differentiation|downregulation of hemopoietic stem cell differentiation|inhibition of haemopoietic stem cell differentiation|downregulation of haematopoietic stem cell differentiation|negative regulation of haemopoietic stem cell differentiation|downregulation of hematopoietic stem cell differentiation|negative regulation of hemopoietic stem cell differentiation|downregulation of haemopoietic stem cell differentiation|down regulation of hemopoietic stem cell differentiation|down-regulation of hematopoietic stem cell differentiation|down-regulation of haematopoietic stem cell differentiation|down-regulation of haemopoietic stem cell differentiation|inhibition of hematopoietic stem cell differentiation|inhibition of hemopoietic stem cell differentiation|down regulation of haemopoietic stem cell differentiation|down-regulation of hemopoietic stem cell differentiation|negative regulation of haematopoietic stem cell differentiation|down regulation of hematopoietic stem cell differentiation|down regulation of haematopoietic stem cell differentiation							ss	2013-04-02T05:19:14Z					biological_process											owl:Class	
GO:1902036	biolink:NamedThing	regulation of hematopoietic stem cell differentiation	Any process that modulates the frequency, rate or extent of hematopoietic stem cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	regulation of hemopoietic stem cell differentiation|regulation of haemopoietic stem cell differentiation|regulation of haematopoietic stem cell differentiation							ss	2013-04-02T05:19:09Z					biological_process											owl:Class	
GO:1904601	biolink:NamedThing	protein localization to actin fusion focus	A process in which a protein is transported to, or maintained in, a location within an actin fusion focus.	tmpzr1t_l9r_go_relaxed.owl	protein localisation in actin fusion focus|protein localisation to actin fusion focus|protein localization in actin fusion focus							al	2015-08-26T10:36:22Z					biological_process											owl:Class	
GO:1903119	biolink:NamedThing	protein localization to actin cytoskeleton	A process in which a protein is transported to, or maintained in, the location of an actin cytoskeleton.	tmpzr1t_l9r_go_relaxed.owl	protein localization in actin cytoskeleton|protein localisation to actin cytoskeleton|protein localisation in actin cytoskeleton							mah	2014-06-16T11:27:09Z					biological_process											owl:Class	
GO:1905906	biolink:NamedThing	regulation of amyloid fibril formation	Any process that modulates the frequency, rate or extent of amyloid fibril formation.	tmpzr1t_l9r_go_relaxed.owl	regulation of amyloid structure assembly|regulation of amyloid structure formation|regulation of amyloid fibril assembly					Although deposition of amyloid fibrils is associated with diseases, e.g. Alzheimer's disease, amyloid formation is a normal process. Disease occurs when the balance between amyloid formation and clearance is disrupted (reviewed e.g. in PMID:29654159 and PMID:28937655). An example of a normal amyloid complex is composed of human RIP1 and RIP3 kinases  (PMID:22817896).		bc	2017-02-03T15:43:48Z					biological_process											owl:Class	
GO:0009650	biolink:NamedThing	UV protection	Any process in which an organism or cell protects itself from ultraviolet radiation (UV), which may also result in resistance to repeated exposure to UV.	tmpzr1t_l9r_go_relaxed.owl	ultraviolet tolerance|UV tolerance|ultraviolet resistance|UV resistance|ultraviolet protection													biological_process											owl:Class	
GO:0009411	biolink:NamedThing	response to UV	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ultraviolet radiation (UV light) stimulus. Ultraviolet radiation is electromagnetic radiation with a wavelength in the range of 10 to 380 nanometers.	tmpzr1t_l9r_go_relaxed.owl	response to UV light stimulus|response to ultraviolet radiation stimulus|response to UV radiation stimulus|response to ultraviolet light stimulus													biological_process											owl:Class	
GO:0055004	biolink:NamedThing	atrial cardiac myofibril assembly	The process whose specific outcome is the progression of the atrial cardiac myofibril over time, from its formation to the mature structure. A cardiac myofibril is a myofibril specific to cardiac muscle cells.	tmpzr1t_l9r_go_relaxed.owl	atrial heart myofibril development|atrial cardiac myofibril development													biological_process											owl:Class	
GO:0055003	biolink:NamedThing	cardiac myofibril assembly	The process whose specific outcome is the progression of the cardiac myofibril over time, from its formation to the mature structure. A cardiac myofibril is a myofibril specific to cardiac muscle cells.	tmpzr1t_l9r_go_relaxed.owl	cardiac myofibril development|cardiac myofibril morphogenesis|heart myofibril assembly													biological_process											owl:Class	
GO:0040013	biolink:NamedThing	negative regulation of locomotion	Any process that stops, prevents, or reduces the frequency, rate or extent of locomotion of a cell or organism.	tmpzr1t_l9r_go_relaxed.owl	inhibition of locomotion|downregulation of locomotion|down-regulation of locomotion|down regulation of locomotion													biological_process											owl:Class	
GO:0048519	biolink:NamedThing	negative regulation of biological process	Any process that stops, prevents, or reduces the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.	tmpzr1t_l9r_go_relaxed.owl	down regulation of biological process|down-regulation of biological process|downregulation of biological process|inhibition of biological process|negative regulation of physiological process											GO:0043118		biological_process											owl:Class	
GO:0042749	biolink:NamedThing	regulation of circadian sleep/wake cycle	Any process that modulates the frequency, rate or extent of the circadian sleep/wake cycle.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0042752	biolink:NamedThing	regulation of circadian rhythm	Any process that modulates the frequency, rate or extent of a circadian rhythm. A circadian rhythm is a biological process in an organism that recurs with a regularity of approximately 24 hours.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1903579	biolink:NamedThing	negative regulation of ATP metabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of ATP metabolic process.	tmpzr1t_l9r_go_relaxed.owl	down regulation of ATP metabolic process|negative regulation of ATP metabolism|downregulation of ATP metabolic process|inhibition of ATP metabolic process|inhibition of ATP metabolism|downregulation of ATP metabolism|down-regulation of ATP metabolic process|down regulation of ATP metabolism|down-regulation of ATP metabolism							sl	2014-10-30T19:04:33Z					biological_process											owl:Class	
GO:1900847	biolink:NamedThing	negative regulation of naphtho-gamma-pyrone biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of naphtho-gamma-pyrone biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	inhibition of naphtho-gamma-pyrone biosynthetic process|down-regulation of naphtho-gamma-pyrone biosynthetic process|down regulation of naphtho-gamma-pyrone biosynthetic process|downregulation of naphtho-gamma-pyrone biosynthetic process							di	2012-06-07T09:43:03Z					biological_process											owl:Class	
GO:0051489	biolink:NamedThing	regulation of filopodium assembly	Any process that modulates the frequency, rate or extent of the assembly of a filopodium, a thin, stiff protrusion extended by the leading edge of a motile cell such as a crawling fibroblast or amoeba, or an axonal growth cone.	tmpzr1t_l9r_go_relaxed.owl	regulation of filopodia biosynthesis|regulation of filopodium formation|regulation of filopodia formation													biological_process											owl:Class	
GO:0120032	biolink:NamedThing	regulation of plasma membrane bounded cell projection assembly	Any process that modulates the rate, frequency, or extent of plasma membrane bounded cell projection assembly.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/13298						krc	2017-04-26T04:27:04Z					biological_process											owl:Class	
GO:0002218	biolink:NamedThing	activation of innate immune response	Any process that initiates an innate immune response. Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens. Examples of this process include activation of the hypersensitive response of Arabidopsis thaliana and activation of any NOD or TLR signaling pathway in vertebrate species.	tmpzr1t_l9r_go_relaxed.owl												GO:0002219		biological_process											owl:Class	
GO:0045737	biolink:NamedThing	positive regulation of cyclin-dependent protein serine/threonine kinase activity	Any process that activates or increases the frequency, rate or extent of CDK activity.	tmpzr1t_l9r_go_relaxed.owl	up regulation of cyclin-dependent protein kinase activity|upregulation of cyclin-dependent protein kinase activity|up-regulation of cyclin-dependent protein kinase activity|positive regulation of CDK activity|positive regulation of cyclin-dependent protein kinase activity|activation of cyclin-dependent protein kinase activity|stimulation of cyclin-dependent protein kinase activity													biological_process											owl:Class	
GO:1904031	biolink:NamedThing	positive regulation of cyclin-dependent protein kinase activity	Any process that activates or increases the frequency, rate or extent of cyclin-dependent protein kinase activity.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of cyclin-dependent protein kinase activity|activation of cyclin-dependent protein kinase activity|up regulation of cyclin-dependent protein kinase activity|upregulation of cyclin-dependent protein kinase activity							als	2015-03-13T15:43:50Z					biological_process											owl:Class	
GO:1901430	biolink:NamedThing	positive regulation of syringal lignin biosynthetic process	Any process that activates or increases the frequency, rate or extent of syringal lignin biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	up regulation of syringal lignin anabolism|positive regulation of syringal lignin formation|positive regulation of syringal lignin biosynthesis|up regulation of syringal lignin formation|upregulation of syringal lignin anabolism|activation of syringal lignin biosynthesis|up regulation of syringal lignin biosynthetic process|activation of syringal lignin synthesis|up-regulation of syringal lignin biosynthesis|up regulation of syringal lignin synthesis|activation of syringal lignin biosynthetic process|up-regulation of syringal lignin synthesis|activation of syringal lignin formation|up-regulation of syringal lignin anabolism|up-regulation of S-lignin biosynthetic process|upregulation of syringal lignin formation|up regulation of syringal lignin biosynthesis|upregulation of S-lignin biosynthetic process|positive regulation of S-lignin biosynthetic process|up-regulation of syringal lignin formation|activation of S-lignin biosynthetic process|positive regulation of syringal lignin synthesis|upregulation of syringal lignin biosynthesis|positive regulation of syringal lignin anabolism|upregulation of syringal lignin synthesis|up-regulation of syringal lignin biosynthetic process|activation of syringal lignin anabolism|upregulation of syringal lignin biosynthetic process|up regulation of S-lignin biosynthetic process							tb	2012-10-01T20:15:09Z					biological_process											owl:Class	
GO:0019404	biolink:NamedThing	galactitol catabolic process	The chemical reactions and pathways resulting in the breakdown of galactitol, the hexitol derived by the reduction of the aldehyde group of either D- or L-galactose.	tmpzr1t_l9r_go_relaxed.owl	galactitol degradation|galactitol catabolism|galactitol breakdown				MetaCyc:GALACTITOLCAT-PWY									biological_process											owl:Class	
GO:0019407	biolink:NamedThing	hexitol catabolic process	The chemical reactions and pathways resulting in the breakdown of hexitols, any alditol with a chain of six carbon atoms in the molecule.	tmpzr1t_l9r_go_relaxed.owl	hexitol degradation|hexitol catabolism|hexitol breakdown													biological_process											owl:Class	
GO:0060218	biolink:NamedThing	hematopoietic stem cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a hematopoietic stem cell. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells.	tmpzr1t_l9r_go_relaxed.owl	haematopoietic stem cell differentiation|haemopoietic stem cell differentiation|hemopoietic stem cell differentiation													biological_process											owl:Class	
GO:0002244	biolink:NamedThing	hematopoietic progenitor cell differentiation	The process in which precursor cell type acquires the specialized features of a hematopoietic progenitor cell, a class of cell types including myeloid progenitor cells and lymphoid progenitor cells.	tmpzr1t_l9r_go_relaxed.owl	haemopoietic progenitor cell differentiation|hemopoietic progenitor cell differentiation|haematopoietic progenitor cell differentiation													biological_process											owl:Class	
GO:0031355	biolink:NamedThing	integral component of plastid outer membrane	The component of the plastid outer membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.	tmpzr1t_l9r_go_relaxed.owl	integral to plastid outer membrane													cellular_component											owl:Class	
GO:0016021	biolink:NamedThing	integral component of membrane	The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.	tmpzr1t_l9r_go_relaxed.owl	integral to membrane|transmembrane				Wikipedia:Transmembrane_protein									cellular_component											owl:Class	
GO:0070760	biolink:NamedThing	positive regulation of interleukin-35-mediated signaling pathway	Any process that increases the rate, frequency or extent of the series of molecular events generated as a consequence of interleukin-35 binding to a cell surface receptor.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of IL-35-mediated signaling pathway|positive regulation of interleukin-35-mediated signalling pathway							mah	2009-06-23T02:06:16Z					biological_process											owl:Class	
GO:0001934	biolink:NamedThing	positive regulation of protein phosphorylation	Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to amino acids within a protein.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of protein amino acid phosphorylation|upregulation of protein amino acid phosphorylation|up regulation of protein amino acid phosphorylation|positive regulation of protein amino acid phosphorylation|stimulation of protein amino acid phosphorylation|activation of protein amino acid phosphorylation													biological_process											owl:Class	
GO:0061415	biolink:NamedThing	negative regulation of transcription from RNA polymerase II promoter by a nonfermentable carbon source	A transcription regulation process in which the presence of a nonfermentable carbon source leads to a decrease of the frequency, rate, or extent of transcription, from an RNA polymerase II promoter, of specific genes involved in the metabolism of other carbon sources.	tmpzr1t_l9r_go_relaxed.owl								dph	2012-01-23T11:33:08Z					biological_process											owl:Class	
GO:0000437	biolink:NamedThing	carbon catabolite repression of transcription from RNA polymerase II promoter	A transcription regulation process in which the presence of one carbon source leads to a decrease in the frequency, rate, or extent of transcription, from an RNA polymerase II promoter, of specific genes involved in the metabolism of other carbon sources.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of transcription from RNA polymerase II promoter by carbon catabolites													biological_process											owl:Class	
GO:0031283	biolink:NamedThing	negative regulation of guanylate cyclase activity	Any process that stops, prevents, or reduces the frequency, rate or extent of guanylate cyclase activity.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of guanylate cyclase activity|downregulation of guanylate cyclase activity|inhibition of guanylate cyclase activity|down regulation of guanylate cyclase activity													biological_process											owl:Class	
GO:0031280	biolink:NamedThing	negative regulation of cyclase activity	Any process that stops or reduces the activity of a cyclase.	tmpzr1t_l9r_go_relaxed.owl	down regulation of cyclase activity|inhibition of cyclase activity|downregulation of cyclase activity|down-regulation of cyclase activity													biological_process											owl:Class	
GO:0060891	biolink:NamedThing	limb granular cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a limb epidermal granular cell.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-08-13T01:33:14Z					biological_process											owl:Class	
GO:0030216	biolink:NamedThing	keratinocyte differentiation	The process in which a relatively unspecialized cell acquires specialized features of a keratinocyte.	tmpzr1t_l9r_go_relaxed.owl	keratinocyte cell differentiation													biological_process											owl:Class	
GO:0015035	biolink:NamedThing	protein-disulfide reductase activity	Catalysis of the reaction: a protein with reduced sulfide groups = a protein with oxidized disulfide bonds.	tmpzr1t_l9r_go_relaxed.owl	protein disulfide oxidoreductase activity|haem lyase disulphide oxidoreductase activity|peptide disulfide oxidoreductase activity|peptide disulphide oxidoreductase activity|protein disulfide-oxidoreductase activity|protein disulphide oxidoreductase activity|heme lyase disulfide oxidoreductase activity	https://github.com/geneontology/go-ontology/issues/20219			Reactome:R-HSA-3299753|MetaCyc:DISULFOXRED-RXN|Reactome:R-HSA-1307802							GO:0008895|GO:0015037		molecular_function											owl:Class	
GO:0001222	biolink:NamedThing	transcription corepressor binding	Binding to a transcription corepressor, a protein involved in negative regulation of transcription via protein-protein interactions with transcription factors and other proteins that negatively regulate transcription. Transcription corepressors do not bind DNA directly, but rather mediate protein-protein interactions between repressing transcription factors and the basal transcription machinery.	tmpzr1t_l9r_go_relaxed.owl	RNA polymerase II transcription corepressor binding	https://github.com/geneontology/go-ontology/issues/19354						krc	2012-04-16T03:27:26Z			GO:0001226		molecular_function											owl:Class	
GO:0001221	biolink:NamedThing	transcription coregulator binding	Binding to a transcription coregulator, a protein involved in regulation of transcription via protein-protein interactions with transcription factors and other transcription regulatory proteins. Cofactors do not bind DNA directly, but rather mediate protein-protein interactions between regulatory transcription factors and the basal transcription machinery.	tmpzr1t_l9r_go_relaxed.owl	RNA polymerase II transcription coregulator binding|RNA polymerase II transcription cofactor binding|transcription cofactor binding	https://github.com/geneontology/go-ontology/issues/19354						krc	2012-04-16T03:19:05Z			GO:0001224		molecular_function											owl:Class	
GO:0003258	biolink:NamedThing	regulation of transcription from RNA polymerase II promoter involved in endocardial precursor cell differentiation	Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the differentiation of an endocardial precursor cell.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-10-15T01:10:34Z					biological_process											owl:Class	
GO:1901213	biolink:NamedThing	regulation of transcription from RNA polymerase II promoter involved in heart development	Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the development of the heart over time.	tmpzr1t_l9r_go_relaxed.owl	regulation of global transcription from Pol II promoter involved in dorsal vessel development|regulation of transcription from RNA polymerase II promoter, global involved in cardiac development|regulation of gene-specific transcription from RNA polymerase II promoter involved in cardiac development|regulation of transcription from RNA polymerase II promoter, global involved in heart development|regulation of transcription from Pol II promoter involved in heart development|regulation of transcription from RNA polymerase II promoter involved in cardiac development|regulation of transcription from Pol II promoter involved in cardiac development|regulation of global transcription from Pol II promoter involved in cardiac development|regulation of gene-specific transcription from RNA polymerase II promoter involved in dorsal vessel development|global transcription regulation from Pol II promoter involved in heart development|regulation of transcription from Pol II promoter involved in dorsal vessel development|regulation of transcription from RNA polymerase II promoter involved in dorsal vessel development|regulation of gene-specific transcription from RNA polymerase II promoter involved in heart development|regulation of global transcription from Pol II promoter involved in heart development|global transcription regulation from Pol II promoter involved in cardiac development|regulation of transcription from RNA polymerase II promoter, global involved in dorsal vessel development|global transcription regulation from Pol II promoter involved in dorsal vessel development							rl	2012-07-31T07:26:45Z					biological_process											owl:Class	
GO:0032502	biolink:NamedThing	developmental process	A biological process whose specific outcome is the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition.	tmpzr1t_l9r_go_relaxed.owl	single-organism developmental process|development							jl	2012-12-19T12:21:31Z			GO:0044767		biological_process											owl:Class	
GO:0071295	biolink:NamedThing	cellular response to vitamin	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-12-10T04:27:24Z					biological_process											owl:Class	
GO:0031670	biolink:NamedThing	cellular response to nutrient	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nutrient stimulus.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0032092	biolink:NamedThing	positive regulation of protein binding	Any process that activates or increases the frequency, rate or extent of protein binding.	tmpzr1t_l9r_go_relaxed.owl	upregulation of protein binding|up-regulation of protein binding|activation of protein binding|stimulation of protein binding|up regulation of protein binding													biological_process											owl:Class	
GO:0043393	biolink:NamedThing	regulation of protein binding	Any process that modulates the frequency, rate or extent of protein binding.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0034923	biolink:NamedThing	phenanthrene-4,5-dicarboxylate decarboxylase activity	Catalysis of the reaction: phenanthrene-4,5-dicarboxylate + H+ = phenanthrene-4-carboxylate + CO2.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0937									molecular_function											owl:Class	
GO:0016463	biolink:NamedThing	P-type zinc transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Zn2+(in) -> ADP + phosphate + Zn2+(out).	tmpzr1t_l9r_go_relaxed.owl	zinc exporting ATPase activity|zinc-translocating P-type ATPase activity|Zn(2+)-exporting ATPase activity|Zn2+-exporting ATPase activity|zinc-exporting ATPase activity|ATP phosphohydrolase (Zn2+-exporting)|P1B-type ATPase activity|P(1B)-type ATPase activity|zinc transmembrane transporter activity, phosphorylative mechanism				RHEA:20621|MetaCyc:3.6.3.5-RXN|EC:7.2.2.12									molecular_function											owl:Class	
GO:0015662	biolink:NamedThing	P-type ion transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O = ADP + phosphate, to directly drive the transport of ions across a membrane. The reaction is characterized by the transient formation of a high-energy aspartyl-phosphoryl-enzyme intermediate.	tmpzr1t_l9r_go_relaxed.owl	zinc, cadmium, cobalt, nickel, lead-efflux ATPase activity|P-type ATPase activity|ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism|ion transmembrane transporter activity, phosphorylative mechanism	https://github.com/geneontology/go-ontology/issues/17164			Reactome:R-HSA-429157									molecular_function											owl:Class	
GO:0000054	biolink:NamedThing	ribosomal subunit export from nucleus	The directed movement of a ribosomal subunit from the nucleus into the cytoplasm.	tmpzr1t_l9r_go_relaxed.owl	ribosomal subunit export from cell nucleus|ribosome export from nucleus|ribosomal subunit export out of nucleus|ribosomal subunit transport from nucleus to cytoplasm|ribosomal subunit-nucleus export													biological_process											owl:Class	
GO:0031503	biolink:NamedThing	protein-containing complex localization	A localization process that acts on a protein complex; the complex is transported to, or maintained in, a specific location.	tmpzr1t_l9r_go_relaxed.owl	establishment and maintenance of cellular protein complex localization|protein complex localisation|cellular protein complex localisation|establishment and maintenance of protein complex localization|protein complex localization|cellular protein-containing complex localization|cellular protein complex localization	https://github.com/geneontology/go-ontology/issues/22021										GO:0034629		biological_process											owl:Class	
GO:0050922	biolink:NamedThing	negative regulation of chemotaxis	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a motile cell or organism in response to a specific chemical concentration gradient.	tmpzr1t_l9r_go_relaxed.owl	inhibition of chemotaxis|down-regulation of chemotaxis|downregulation of chemotaxis|down regulation of chemotaxis													biological_process											owl:Class	
GO:0031101	biolink:NamedThing	fin regeneration	The regrowth of fin tissue following its loss or destruction.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1901972	biolink:NamedThing	positive regulation of DNA-5-methylcytosine glycosylase activity	Any process that activates or increases the frequency, rate or extent of DNA-5-methylcytosine glycosylase activity.	tmpzr1t_l9r_go_relaxed.owl	upregulation of DNA-5-methylcytosine glycosylase activity|up-regulation of DNA-5-methylcytosine glycosylase activity|up regulation of DNA-5-methylcytosine glycosylase activity|activation of DNA-5-methylcytosine glycosylase activity							tb	2013-02-25T20:01:34Z					biological_process											owl:Class	
GO:1901971	biolink:NamedThing	regulation of DNA-5-methylcytosine glycosylase activity	Any process that modulates the frequency, rate or extent of DNA-5-methylcytosine glycosylase activity.	tmpzr1t_l9r_go_relaxed.owl								tb	2013-02-25T20:01:29Z					biological_process											owl:Class	
GO:0047484	biolink:NamedThing	regulation of response to osmotic stress	Any process that modulates the rate or extent of the response to osmotic stress.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0099528	biolink:NamedThing	G protein-coupled neurotransmitter receptor activity	Combining with a neurotransmitter and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.	tmpzr1t_l9r_go_relaxed.owl	G-protein coupled neurotransmitter receptor activity													molecular_function											owl:Class	
GO:0030594	biolink:NamedThing	neurotransmitter receptor activity	Combining with a neurotransmitter and transmitting the signal to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl						A strict definition of neurotransmitter receptor activity would limit its use to receptor activity at the postsynaptic membrane as part of synaptic transmission, but we recognize that usage is often much broader than this. For the strict use case, please see 'postsynaptic neurotransmitter receptor activity'								molecular_function											owl:Class	
GO:0061889	biolink:NamedThing	negative regulation of astrocyte activation	Any process that decreases the frequency, rate or extent of astrocyte activation.	tmpzr1t_l9r_go_relaxed.owl								dph	2017-06-01T22:29:43Z					biological_process											owl:Class	
GO:0050866	biolink:NamedThing	negative regulation of cell activation	Any process that stops, prevents, or reduces the frequency, rate or extent of cell activation.	tmpzr1t_l9r_go_relaxed.owl	downregulation of cell activation|down regulation of cell activation|down-regulation of cell activation|inhibition of cell activation													biological_process											owl:Class	
GO:1901248	biolink:NamedThing	positive regulation of lung ciliated cell differentiation	Any process that activates or increases the frequency, rate or extent of lung ciliated cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	up regulation of lung ciliated cell differentiation|upregulation of lung ciliated cell differentiation|up-regulation of lung ciliated cell differentiation|activation of lung ciliated cell differentiation							vk	2012-08-08T08:59:05Z					biological_process											owl:Class	
GO:0001805	biolink:NamedThing	positive regulation of type III hypersensitivity	Any process that activates or increases the frequency, rate or extent of type III hypersensitivity, a type of inflammatory response.	tmpzr1t_l9r_go_relaxed.owl	stimulation of type III hypersensitivity|upregulation of type III hypersensitivity|activation of type III hypersensitivity|up-regulation of type III hypersensitivity|up regulation of type III hypersensitivity													biological_process											owl:Class	
GO:2000559	biolink:NamedThing	regulation of CD24 production	Any process that modulates the frequency, rate or extent of CD24 biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of CD24 formation|regulation of CD24 biosynthesis|regulation of CD24 anabolism|regulation of CD24 synthesis|regulation of CD24 biosynthetic process							ebc	2011-04-03T08:56:56Z					biological_process											owl:Class	
GO:0010559	biolink:NamedThing	regulation of glycoprotein biosynthetic process	Any process that modulates the rate, frequency, or extent of the chemical reactions and pathways resulting in the formation of a glycoprotein, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1905765	biolink:NamedThing	negative regulation of protection from non-homologous end joining at telomere	Any process that stops, prevents or reduces the frequency, rate or extent of protection from non-homologous end joining at telomere.	tmpzr1t_l9r_go_relaxed.owl	inhibition of protection from NHEJ-mediated telomere fusion|down regulation of protection from NHEJ-mediated telomere fusion|inhibition of protection from non-homologous end joining at telomere|down regulation of protection from non-homologous end joining at telomere|negative regulation of protection from NHEJ-mediated telomere fusion|down-regulation of protection from non-homologous end joining at telomere|downregulation of protection from non-homologous end joining at telomere|down-regulation of protection from NHEJ-mediated telomere fusion|downregulation of protection from NHEJ-mediated telomere fusion							nc	2016-12-20T11:28:30Z					biological_process											owl:Class	
GO:0006879	biolink:NamedThing	cellular iron ion homeostasis	Any process involved in the maintenance of an internal steady state of iron ions at the level of a cell.	tmpzr1t_l9r_go_relaxed.owl	iron homeostasis													biological_process											owl:Class	
GO:0055072	biolink:NamedThing	iron ion homeostasis	Any process involved in the maintenance of an internal steady state of iron ions within an organism or cell.	tmpzr1t_l9r_go_relaxed.owl	iron homeostasis													biological_process											owl:Class	
GO:1900328	biolink:NamedThing	negative regulation of mannotriose transport	Any process that stops, prevents or reduces the frequency, rate or extent of mannotriose transport.	tmpzr1t_l9r_go_relaxed.owl	down regulation of mannotriose transport|downregulation of mannotriose transport|down-regulation of mannotriose transport|inhibition of mannotriose transport							tt	2012-04-06T01:50:13Z					biological_process											owl:Class	
GO:1900327	biolink:NamedThing	regulation of mannotriose transport	Any process that modulates the frequency, rate or extent of mannotriose transport.	tmpzr1t_l9r_go_relaxed.owl								tt	2012-04-06T01:50:05Z					biological_process											owl:Class	
GO:1900721	biolink:NamedThing	positive regulation of uterine smooth muscle relaxation	Any process that activates or increases the frequency, rate or extent of uterine smooth muscle relaxation.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of smooth muscle relaxation of the uterus|up regulation of uterine smooth muscle relaxation|up-regulation of smooth muscle relaxation of the uterus|up regulation of smooth muscle relaxation of the uterus|upregulation of uterine smooth muscle relaxation|activation of smooth muscle relaxation of the uterus|activation of uterine smooth muscle relaxation|up-regulation of uterine smooth muscle relaxation|upregulation of smooth muscle relaxation of the uterus							jl	2012-05-24T03:12:57Z					biological_process											owl:Class	
GO:0046223	biolink:NamedThing	aflatoxin catabolic process	The chemical reactions and pathways resulting in the breakdown of aflatoxin, a fungal metabolite found as a contaminant in moldy grains that induces liver cancer. Aflatoxin induces a G to T transversion at codon 249 of p53, leading to its inactivation. Aflatoxin is converted to a chemical carcinogen by P450.	tmpzr1t_l9r_go_relaxed.owl	aflatoxin degradation|aflatoxin catabolism|aflatoxin breakdown													biological_process											owl:Class	
GO:0043387	biolink:NamedThing	mycotoxin catabolic process	The chemical reactions and pathways resulting in the breakdown of a mycotoxin, any poisonous substance produced by a fungus.	tmpzr1t_l9r_go_relaxed.owl	mycotoxin degradation|mycotoxin catabolism|mycotoxin breakdown													biological_process											owl:Class	
GO:0046641	biolink:NamedThing	positive regulation of alpha-beta T cell proliferation	Any process that activates or increases the frequency, rate or extent of alpha-beta T cell proliferation.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of alpha-beta T-cell proliferation|upregulation of alpha-beta T cell proliferation|stimulation of alpha-beta T cell proliferation|up-regulation of alpha-beta T cell proliferation|up regulation of alpha-beta T cell proliferation|activation of alpha-beta T cell proliferation|positive regulation of alpha-beta T lymphocyte proliferation|positive regulation of alpha-beta T-lymphocyte proliferation													biological_process											owl:Class	
GO:0046635	biolink:NamedThing	positive regulation of alpha-beta T cell activation	Any process that activates or increases the frequency, rate or extent of alpha-beta T cell activation.	tmpzr1t_l9r_go_relaxed.owl	activation of alpha-beta T cell activation|positive regulation of alpha-beta T lymphocyte activation|upregulation of alpha-beta T cell activation|positive regulation of alpha-beta T-lymphocyte activation|up-regulation of alpha-beta T cell activation|positive regulation of alpha-beta T-cell activation|up regulation of alpha-beta T cell activation|stimulation of alpha-beta T cell activation													biological_process											owl:Class	
GO:1990329	biolink:NamedThing	IscS-TusA complex	A heterotetrameric protein complex involved in the sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm5s2U) at tRNA wobble positions. In E. coli it consists of a central IscS dimer with the two TusA protomers bound to one of the IscS units each via persulfide (-SSH) groups.	tmpzr1t_l9r_go_relaxed.owl								bhm	2014-03-17T10:00:47Z					cellular_component											owl:Class	
GO:1990221	biolink:NamedThing	L-cysteine desulfurase complex	A protein complex capable of cysteine desulfurase activity decomposing L-cysteine to L-alanine and sulfur. It belongs to a ubiquitous family of pyridoxal 5-phosphate (PLP)-dependent enzymes. In E. coli it consists of a SufS dimer.	tmpzr1t_l9r_go_relaxed.owl	NifS|SufS complex|IscS							bhm	2013-10-11T15:36:34Z					cellular_component											owl:Class	
GO:1900025	biolink:NamedThing	negative regulation of substrate adhesion-dependent cell spreading	Any process that stops, prevents or reduces the frequency, rate or extent of substrate adhesion-dependent cell spreading.	tmpzr1t_l9r_go_relaxed.owl	down regulation of substrate adhesion-dependent cell spreading|negative regulation of substrate adhesion dependent cell spreading|down regulation of cell spreading during cell substrate adhesion|negative regulation of cell spreading during cell substrate adhesion|down regulation of substrate adhesion dependent cell spreading							yaf	2012-01-12T05:00:43Z					biological_process											owl:Class	
GO:0010771	biolink:NamedThing	negative regulation of cell morphogenesis involved in differentiation	Any process that decreases the frequency, rate or extent of cell morphogenesis contributing to cell differentiation. Cell morphogenesis involved in differentiation is the change in form (cell shape and size) that occurs when relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:2000888	biolink:NamedThing	arabinoxylan-containing compound catabolic process	The chemical reactions and pathways resulting in the breakdown of an arabinoxylan.	tmpzr1t_l9r_go_relaxed.owl	arabinoxylan catabolic process|arabinoxylan catabolism							jl	2011-07-28T09:31:50Z					biological_process											owl:Class	
GO:0045493	biolink:NamedThing	xylan catabolic process	The chemical reactions and pathways resulting in the breakdown of xylan, a polymer containing a beta-1,4-linked D-xylose backbone.	tmpzr1t_l9r_go_relaxed.owl	xylan degradation|xylan breakdown|xylan catabolism													biological_process											owl:Class	
GO:0004072	biolink:NamedThing	aspartate kinase activity	Catalysis of the reaction: L-aspartate + ATP = 4-phospho-L-aspartate + ADP + H(+).	tmpzr1t_l9r_go_relaxed.owl	ATP:L-aspartate 4-phosphotransferase activity|aspartic kinase activity|aspartokinase activity|beta-aspartokinase activity				EC:2.7.2.4|RHEA:23776|KEGG_REACTION:R00480|MetaCyc:ASPARTATEKIN-RXN									molecular_function											owl:Class	
GO:0019202	biolink:NamedThing	amino acid kinase activity	Catalysis of the transfer of a phosphate group, usually from ATP, to an amino acid substrate.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0032373	biolink:NamedThing	positive regulation of sterol transport	Any process that activates or increases the frequency, rate or extent of the directed movement of sterols into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	stimulation of sterol transport|up-regulation of sterol transport|activation of sterol transport|up regulation of sterol transport|upregulation of sterol transport													biological_process											owl:Class	
GO:0032370	biolink:NamedThing	positive regulation of lipid transport	Any process that activates or increases the frequency, rate or extent of the directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	activation of lipid transport|stimulation of lipid transport|upregulation of lipid transport|up regulation of lipid transport|up-regulation of lipid transport													biological_process											owl:Class	
GO:0019621	biolink:NamedThing	creatinine catabolic process to formate	The chemical reactions and pathways resulting in the breakdown of creatinine into other compounds, including formate.	tmpzr1t_l9r_go_relaxed.owl	creatinine degradation to formate|creatinine breakdown to formate				MetaCyc:CRNFORCAT-PWY									biological_process											owl:Class	
GO:0006602	biolink:NamedThing	creatinine catabolic process	The chemical reactions and pathways resulting in the breakdown of creatinine, 2-amino-1,5-dihydro-1-methyl-4H-imidazol-4-one, an end product of creatine metabolism and a normal constituent of urine.	tmpzr1t_l9r_go_relaxed.owl	creatinine degradation|creatinine catabolism|creatinine breakdown													biological_process											owl:Class	
GO:1901666	biolink:NamedThing	positive regulation of NAD+ ADP-ribosyltransferase activity	Any process that activates or increases the frequency, rate or extent of NAD+ ADP-ribosyltransferase activity.	tmpzr1t_l9r_go_relaxed.owl	activation of ADP-ribosyltransferase (polymerizing) activity|positive regulation of poly(ADP-ribose)polymerase activity|activation of poly(ADP-ribose)polymerase activity|up-regulation of NAD+ ADP-ribosyltransferase activity|up-regulation of ADP-ribosyltransferase (polymerizing) activity|activation of NAD+ ADP-ribosyltransferase activity|activation of poly(ADP-ribose) synthetase activity|upregulation of ADP-ribosyltransferase (polymerizing) activity|positive regulation of poly(ADP-ribose) synthase activity|up regulation of NAD+ ADP-ribosyltransferase activity|upregulation of poly(ADP-ribose) synthetase activity|activation of poly(ADP-ribose) synthase activity|positive regulation of ADP-ribosyltransferase (polymerizing) activity|up-regulation of poly(adenosine diphosphate ribose) polymerase activity|positive regulation of NAD ADP-ribosyltransferase activity|up regulation of ADP-ribosyltransferase (polymerizing) activity|up regulation of poly(ADP-ribose) synthase activity|up-regulation of NAD ADP-ribosyltransferase activity|up-regulation of poly(ADP-ribose) synthase activity|up regulation of NAD+:poly(adenine-diphosphate-D-ribosyl)-acceptor ADP-D-ribosyl-transferase activity|positive regulation of NAD+:poly(adenine-diphosphate-D-ribosyl)-acceptor ADP-D-ribosyl-transferase activity|up regulation of poly(ADP-ribose)polymerase activity|positive regulation of poly(adenosine diphosphate ribose) polymerase activity|up-regulation of poly(ADP-ribose)polymerase activity|up-regulation of NAD+:poly(adenine-diphosphate-D-ribosyl)-acceptor ADP-D-ribosyl-transferase activity|upregulation of poly(ADP-ribose) synthase activity|positive regulation of poly(ADP-ribose) synthetase activity|activation of poly(adenosine diphosphate ribose) polymerase activity|activation of NAD ADP-ribosyltransferase activity|upregulation of NAD+ ADP-ribosyltransferase activity|up regulation of poly(adenosine diphosphate ribose) polymerase activity|activation of NAD+:poly(adenine-diphosphate-D-ribosyl)-acceptor ADP-D-ribosyl-transferase activity|upregulation of poly(adenosine diphosphate ribose) polymerase activity|up regulation of NAD ADP-ribosyltransferase activity|up regulation of poly(ADP-ribose) synthetase activity|upregulation of poly(ADP-ribose)polymerase activity|upregulation of NAD+:poly(adenine-diphosphate-D-ribosyl)-acceptor ADP-D-ribosyl-transferase activity|upregulation of NAD ADP-ribosyltransferase activity|up-regulation of poly(ADP-ribose) synthetase activity							vk	2012-11-20T18:50:20Z					biological_process											owl:Class	
GO:1990748	biolink:NamedThing	cellular detoxification	Any process carried out at the cellular level that reduces or removes the toxicity of a toxic substance. These may include transport of the toxic substance away from sensitive areas and to compartments or complexes whose purpose is sequestration of the toxic substance.	tmpzr1t_l9r_go_relaxed.owl								vw	2015-05-18T16:17:46Z					biological_process											owl:Class	
GO:0051737	biolink:NamedThing	GTP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity	Catalysis of the reaction: GTP + 5'-dephospho-DNA = GDP + 5'-phospho-DNA.	tmpzr1t_l9r_go_relaxed.owl	GTP-dependent DNA kinase activity|GTP-dependent polydeoxyribonucleotide kinase activity|GTP-dependent polynucleotide 5'-hydroxyl-kinase activity|GTP-dependent DNA 5'-hydroxyl-kinase activity|GTP:5'-dephosphopolydeoxyribonucleotide 5'-phosphotransferase activity													molecular_function											owl:Class	
GO:0051735	biolink:NamedThing	GTP-dependent polynucleotide kinase activity	Catalysis of the reaction: GTP + 5'-dephosphopolynucleotide = GDP + 5'-phosphopolynucleotide. The polynucleotide may be DNA or RNA.	tmpzr1t_l9r_go_relaxed.owl	GTP:5'-dephosphopolynucleotide 5'-phosphotransferase activity|GTP-dependent polynucleotide 5'-hydroxyl-kinase activity													molecular_function											owl:Class	
GO:0086056	biolink:NamedThing	voltage-gated calcium channel activity involved in AV node cell action potential	Enables the transmembrane transfer of a calcium ion by a voltage-gated channel across the plasma membrane of an AV node cardiac muscle cell that contributes to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.	tmpzr1t_l9r_go_relaxed.owl	voltage-gated calcium channel activity involved in atrioventricular node cardiac muscle cell action potential|voltage-gated calcium channel activity involved in AV node cardiac muscle cell action potential							dph	2011-11-17T12:24:22Z					molecular_function											owl:Class	
GO:0086007	biolink:NamedThing	voltage-gated calcium channel activity involved in cardiac muscle cell action potential	Enables the transmembrane transfer of a calcium ion by a voltage-gated channel across the plasma membrane of a cardiac muscle cell that contributes to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.	tmpzr1t_l9r_go_relaxed.owl								tb	2011-11-10T08:04:42Z					molecular_function											owl:Class	
GO:1990572	biolink:NamedThing	TERT-RMRP complex	A ribonucleoprotein complex that has RNA-directed RNA polymerase (RdRP) activity, and is composed of telomerase reverse transcriptase (TERT) and the non-coding RNA component of mitochondrial RNA processing endoribonuclease (RMRP).	tmpzr1t_l9r_go_relaxed.owl	telomerase reverse transcriptase:RMRP RNA complex							bf	2014-12-02T11:29:12Z					cellular_component											owl:Class	
GO:0031379	biolink:NamedThing	RNA-directed RNA polymerase complex	A protein complex that possesses RNA-directed RNA polymerase activity.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0021828	biolink:NamedThing	gonadotrophin-releasing hormone neuronal migration to the hypothalamus	The directional movement of a gonadotrophin-releasing hormone producing neuron from the nasal placode to the hypothalamus.	tmpzr1t_l9r_go_relaxed.owl	gonadotropin-releasing hormone neuronal migration to the hypothalamus											GO:0021857		biological_process											owl:Class	
GO:0001764	biolink:NamedThing	neuron migration	The characteristic movement of an immature neuron from germinal zones to specific positions where they will reside as they mature.	tmpzr1t_l9r_go_relaxed.owl	neuron chemotaxis|neuronal migration|neuron guidance				Wikipedia:Neural_development#Neuron_migration|Wikipedia:Neuron_migration									biological_process											owl:Class	
GO:2000676	biolink:NamedThing	positive regulation of type B pancreatic cell apoptotic process	Any process that activates or increases the frequency, rate or extent of type B pancreatic cell apoptotic process.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of pancreatic B cell apoptosis|positive regulation of type B pancreatic cell apoptosis|positive regulation of pancreatic beta cell apoptosis							pr	2011-05-09T11:51:15Z					biological_process											owl:Class	
GO:1904037	biolink:NamedThing	positive regulation of epithelial cell apoptotic process	Any process that activates or increases the frequency, rate or extent of epithelial cell apoptotic process.	tmpzr1t_l9r_go_relaxed.owl	up regulation of epithelial cell apoptosis|upregulation of epithelial cell apoptotic process|positive regulation of epitheliocyte apoptosis|activation of epitheliocyte apoptosis|up-regulation of epitheliocyte apoptosis|up-regulation of epitheliocyte apoptotic process|activation of epitheliocyte apoptotic process|activation of epithelial cell apoptotic process|up regulation of epitheliocyte apoptosis|up-regulation of epithelial cell apoptotic process|upregulation of epitheliocyte apoptotic process|upregulation of epithelial cell apoptosis|upregulation of epitheliocyte apoptosis|positive regulation of epithelial cell apoptosis|positive regulation of epitheliocyte apoptotic process|up regulation of epithelial cell apoptotic process|up regulation of epitheliocyte apoptotic process|activation of epithelial cell apoptosis|up-regulation of epithelial cell apoptosis							sl	2015-03-13T22:05:53Z					biological_process											owl:Class	
GO:0106348	biolink:NamedThing	U2 snRNA adenosine m6 methytransferase activity	Catalysis of the reaction: a adenosine in U2 snRNA + S-adenosyl-L-methionine = an N6-methyl-adenosine in U2 snRNA + S-adenosyl-L-homocysteine + H+.	tmpzr1t_l9r_go_relaxed.owl								hjd	2020-12-18T15:12:57Z					molecular_function											owl:Class	
GO:0106346	biolink:NamedThing	snRNA methyltransferase activity	Catalysis of the transfer of a methyl group from a donor to a nucleoside residue in an snRNA molecule.	tmpzr1t_l9r_go_relaxed.owl								hjd	2020-12-18T15:06:44Z					molecular_function											owl:Class	
GO:0061852	biolink:NamedThing	retrograte transporter complex, Golgi to ER	Transporter complex that recognises, binds and returns endoplasmic reticulum (ER) resident proteins that have trafficked to Golgi compartments. Targets proteins lacking the HDEL motif recognised by COPI-coated vesicles.	tmpzr1t_l9r_go_relaxed.owl	retrograte receptor complex, Golgi to ER|retrograte transporter complex, Golgi to endoplasmic reticulum|ERV41-ERV46 retrograde receptor complex|retrograte receptor complex, Golgi to endoplasmic reticulum					An example of this is ERV41 in Saccharomyces cerevisiae (Q04651) in PMID:16093310 (inferred from direct assay).		dph	2017-02-28T13:56:56Z					cellular_component											owl:Class	
GO:1990351	biolink:NamedThing	transporter complex	A protein complex facilitating transport of molecules (proteins, small molecules, nucleic acids) into, out of or within a cell, or between cells.	tmpzr1t_l9r_go_relaxed.owl						An example of this is GTR1 in human (UniProt symbol P11166) in PMID:15449578 (inferred from direct assay).		bhm	2014-03-26T14:23:27Z					cellular_component											owl:Class	
GO:0001991	biolink:NamedThing	regulation of systemic arterial blood pressure by circulatory renin-angiotensin	The process in which angiotensinogen metabolites in the bloodstream modulate the force with which blood passes through the circulatory system. The process begins when renin is released and cleaves angiotensinogen.	tmpzr1t_l9r_go_relaxed.owl	circulatory renin-angiotensin control of blood pressure|control of blood pressure by circulatory renin-angiotensin|circulatory renin-angiotensin regulation of blood pressure|circulatory renin-angiotensin blood pressure regulation|renin-angiotensin blood pressure control													biological_process											owl:Class	
GO:0003081	biolink:NamedThing	regulation of systemic arterial blood pressure by renin-angiotensin	The process in which renin-angiotensin modulates the force with which blood passes through the circulatory system.	tmpzr1t_l9r_go_relaxed.owl	blood pressure regulation by renin-angiotensin													biological_process											owl:Class	
GO:0032725	biolink:NamedThing	positive regulation of granulocyte macrophage colony-stimulating factor production	Any process that activates or increases the frequency, rate, or extent of granulocyte macrophage colony-stimulating factor production.	tmpzr1t_l9r_go_relaxed.owl	upregulation of granulocyte macrophage colony-stimulating factor production|activation of granulocyte macrophage colony-stimulating factor production|positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process|positive regulation of granulocyte macrophage colony stimulating factor production|up regulation of granulocyte macrophage colony-stimulating factor production|positive regulation of GM-CSF production|up-regulation of granulocyte macrophage colony-stimulating factor production|stimulation of granulocyte macrophage colony-stimulating factor production											GO:0045425		biological_process											owl:Class	
GO:0032645	biolink:NamedThing	regulation of granulocyte macrophage colony-stimulating factor production	Any process that modulates the frequency, rate, or extent of granulocyte macrophage colony-stimulating factor production.	tmpzr1t_l9r_go_relaxed.owl	regulation of granulocyte macrophage colony-stimulating factor biosynthetic process|regulation of granulocyte macrophage colony stimulating factor production|regulation of GM-CSF production											GO:0045423		biological_process											owl:Class	
GO:0106278	biolink:NamedThing	regulation of UDP-N-acetylglucosamine biosynthetic process	Any process that modulates the frequency, rate or extent of the  UDP-N_acetylglucosamine biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of UDP-GlcNAc biosynthetic process|regulation of UDP-N-acetylglucosamine synthesis|regulation of UDP-N-acetylglucosamine biosynthesis|regulation of UDP-N-acetylglucosamine anabolism|regulation of UDP-N-acetylglucosamine formation							hjd	2020-07-09T17:20:49Z					biological_process											owl:Class	
GO:2001172	biolink:NamedThing	positive regulation of glycolytic fermentation to ethanol	Any process that activates or increases the frequency, rate or extent of glucose catabolic process to ethanol.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of ethanol fermentation|positive regulation of glucose fermentation to ethanol							mcc	2011-10-27T02:39:09Z					biological_process											owl:Class	
GO:0010853	biolink:NamedThing	cyclase activator activity	Increases the activity of an enzyme that catalyzes a ring closure reaction.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0097358	biolink:NamedThing	D-leucyl-tRNA(Leu) deacylase activity	Catalysis of the reaction: D-leucyl-tRNA(Leu) = D-leucine + tRNA(Leu). Hydrolysis of the removal of D-leucine from residues in charged tRNA(Leu).	tmpzr1t_l9r_go_relaxed.owl								pr	2012-07-04T09:18:12Z					molecular_function											owl:Class	
GO:0051499	biolink:NamedThing	D-aminoacyl-tRNA deacylase activity	Catalysis of the reaction: D-aminoacyl-tRNA = D-amino acid + tRNA. Hydrolysis of the removal of D-amino acids from residues in charged tRNA.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-15041|EC:3.1.1.96|RHEA:13953									molecular_function											owl:Class	
GO:1901771	biolink:NamedThing	daunorubicin biosynthetic process	The chemical reactions and pathways resulting in the formation of daunorubicin.	tmpzr1t_l9r_go_relaxed.owl	daunorubicin synthesis|daunorubicin biosynthesis|daunorubicin formation|daunorubicin anabolism							yaf	2013-01-15T10:14:33Z					biological_process											owl:Class	
GO:1901663	biolink:NamedThing	quinone biosynthetic process	The chemical reactions and pathways resulting in the formation of quinone.	tmpzr1t_l9r_go_relaxed.owl	quinone cofactor formation|quinone cofactor anabolism|quinone anabolism|quinone biosynthesis|quinone cofactor synthesis|quinone synthesis|quinone cofactor biosynthesis|quinone formation|quinone cofactor biosynthetic process							pr	2012-11-20T14:44:48Z			GO:0045426		biological_process											owl:Class	
GO:0043766	biolink:NamedThing	Sep-tRNA:Cys-tRNA synthase activity	Catalysis of the reaction: O-phospho-L-seryl-tRNACys + sulfide = L-cysteinyl-tRNACys + phosphate.	tmpzr1t_l9r_go_relaxed.owl	SepCysS|O-phosphoseryl-tRNA:cysteinyl-tRNA synthase activity|Sep-tRNA:Cys-tRNA synthetase activity				EC:2.5.1.73|MetaCyc:RXN-10719|RHEA:25686									molecular_function											owl:Class	
GO:0090616	biolink:NamedThing	mitochondrial mRNA 3'-end processing	Any process involved in forming the mature 3' end of an mRNA molecule that derives from the mitochondrial genome.	tmpzr1t_l9r_go_relaxed.owl								tb	2014-10-24T12:45:08Z					biological_process											owl:Class	
GO:0046392	biolink:NamedThing	galactarate catabolic process	The chemical reactions and pathways resulting in the breakdown of galactarate, the anion of galactaric acid.	tmpzr1t_l9r_go_relaxed.owl	D-galactarate degradation|D-galactarate catabolism|galactarate catabolism|D-galactarate breakdown|D-galactarate catabolic process|galactarate degradation|galactarate breakdown				MetaCyc:GALACTARDEG-PWY							GO:0019582		biological_process											owl:Class	
GO:0019580	biolink:NamedThing	galactarate metabolic process	The chemical reactions and pathways involving galactarate, an anion of galactaric acid, the meso-aldaric acid derived from both D- and L-galactose.	tmpzr1t_l9r_go_relaxed.owl	galactarate metabolism|D-galactarate metabolic process|mucic acid metabolism|D-galactarate metabolism|mucic acid metabolic process											GO:0046393		biological_process											owl:Class	
GO:0003724	biolink:NamedThing	RNA helicase activity	Unwinding of an RNA helix, driven by ATP hydrolysis.	tmpzr1t_l9r_go_relaxed.owl	ATP-dependent RNA helicase activity	https://github.com/geneontology/go-ontology/issues/21612			EC:3.6.4.13|MetaCyc:ADENOSINETRIPHOSPHATASE-RXN|Reactome:R-HSA-72647							GO:0004004		molecular_function											owl:Class	
GO:0008186	biolink:NamedThing	ATP-dependent activity, acting on RNA	Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction requires the presence of RNA, and it drives another reaction.	tmpzr1t_l9r_go_relaxed.owl	ATPase activity, acting on RNA|ATPase, acting on RNA|RNA-dependent adenosinetriphosphatase activity|RNA-dependent ATPase activity	https://github.com/geneontology/go-ontology/issues/21775|https://github.com/geneontology/go-ontology/issues/20876										GO:0004010		molecular_function											owl:Class	
GO:1905694	biolink:NamedThing	negative regulation of phosphatidic acid biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of phosphatidic acid biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of phosphatidic acid anabolism|inhibition of phosphatidic acid formation|down-regulation of phosphatidic acid biosynthetic process|negative regulation of phosphatidic acid formation|inhibition of phosphatidic acid biosynthesis|downregulation of phosphatidic acid anabolism|negative regulation of phosphatidic acid biosynthesis|negative regulation of phosphatidic acid synthesis|down-regulation of phosphatidic acid formation|down regulation of phosphatidic acid anabolism|down regulation of phosphatidic acid biosynthesis|down-regulation of phosphatidic acid anabolism|down regulation of phosphatidic acid formation|downregulation of phosphatidic acid biosynthesis|down regulation of phosphatidic acid biosynthetic process|inhibition of phosphatidic acid anabolism|down regulation of phosphatidic acid synthesis|down-regulation of phosphatidic acid synthesis|downregulation of phosphatidic acid biosynthetic process|inhibition of phosphatidic acid biosynthetic process|inhibition of phosphatidic acid synthesis|down-regulation of phosphatidic acid biosynthesis|downregulation of phosphatidic acid synthesis|downregulation of phosphatidic acid formation							bc	2016-11-14T14:48:16Z					biological_process											owl:Class	
GO:1905693	biolink:NamedThing	regulation of phosphatidic acid biosynthetic process	Any process that modulates the frequency, rate or extent of phosphatidic acid biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of phosphatidic acid synthesis|regulation of phosphatidic acid formation|regulation of phosphatidic acid biosynthesis|regulation of phosphatidic acid anabolism							bc	2016-11-14T14:48:09Z					biological_process											owl:Class	
GO:1903062	biolink:NamedThing	regulation of reverse cholesterol transport	Any process that modulates the frequency, rate or extent of reverse cholesterol transport.	tmpzr1t_l9r_go_relaxed.owl								rl	2014-05-28T15:15:27Z					biological_process											owl:Class	
GO:0003370	biolink:NamedThing	cell-cell adhesion involved in mesendodermal cell migration	The attachment of mesendodermal cells to each other that contributes to the establishment of cell polarity that is part of the directed movement of the cells of the mesendoderm.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-12-08T05:33:51Z					biological_process											owl:Class	
GO:0070586	biolink:NamedThing	cell-cell adhesion involved in gastrulation	The attachment of one cell to another cell affecting gastrulation.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-04-24T02:48:23Z					biological_process											owl:Class	
GO:0086084	biolink:NamedThing	cell adhesive protein binding involved in Purkinje myocyte-ventricular cardiac muscle cell communication	Binding to a protein or protein complex that results in the connection of a Purkinje myocyte with an ventricular cardiac muscle cell and contributes to the communication between the two cells.	tmpzr1t_l9r_go_relaxed.owl								dph	2011-11-22T11:13:16Z					molecular_function											owl:Class	
GO:0086080	biolink:NamedThing	protein binding involved in heterotypic cell-cell adhesion	Binding to a protein or protein complex contributing to the adhesion of two different types of cells.	tmpzr1t_l9r_go_relaxed.owl								dph	2011-11-22T10:53:52Z					molecular_function											owl:Class	
GO:1901803	biolink:NamedThing	1,5-anhydro-D-fructose biosynthetic process	The chemical reactions and pathways resulting in the formation of 1,5-anhydro-D-fructose.	tmpzr1t_l9r_go_relaxed.owl	1,5-anhydro-D-fructose formation|1,5-anhydro-D-fructose synthesis|1,5-anhydro-D-fructose biosynthesis|1,5-anhydro-D-fructose anabolism							yaf	2013-01-22T09:56:34Z					biological_process											owl:Class	
GO:0042181	biolink:NamedThing	ketone biosynthetic process	The chemical reactions and pathways resulting in the formation of ketones, a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups.	tmpzr1t_l9r_go_relaxed.owl	ketone anabolism|ketone formation|ketone synthesis|ketone biosynthesis													biological_process											owl:Class	
GO:1900802	biolink:NamedThing	cspyrone B1 biosynthetic process	The chemical reactions and pathways resulting in the formation of cspyrone B1.	tmpzr1t_l9r_go_relaxed.owl	cspyrone B1 anabolism|cspyrone B1 biosynthesis|cspyrone B1 formation|cspyrone B1 synthesis							di	2012-06-04T09:51:06Z					biological_process											owl:Class	
GO:1901336	biolink:NamedThing	lactone biosynthetic process	The chemical reactions and pathways resulting in the formation of lactone.	tmpzr1t_l9r_go_relaxed.owl	lactone biosynthesis|lactone anabolism|lactone formation|lactone synthesis							bf	2012-09-03T10:27:29Z					biological_process											owl:Class	
GO:0014050	biolink:NamedThing	negative regulation of glutamate secretion	Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of glutamate.	tmpzr1t_l9r_go_relaxed.owl	inhibition of glutamate secretion|down-regulation of glutamate secretion|downregulation of glutamate secretion|down regulation of glutamate secretion													biological_process											owl:Class	
GO:1903531	biolink:NamedThing	negative regulation of secretion by cell	Any process that stops, prevents or reduces the frequency, rate or extent of secretion by cell.	tmpzr1t_l9r_go_relaxed.owl	down regulation of secretion by cell|downregulation of secretion by cell|downregulation of cellular secretion|down-regulation of cellular secretion|negative regulation of cellular secretion|inhibition of secretion by cell|inhibition of cellular secretion|down regulation of cellular secretion|down-regulation of secretion by cell							pm	2014-10-08T13:25:08Z					biological_process											owl:Class	
GO:0008204	biolink:NamedThing	ergosterol metabolic process	The chemical reactions and pathways involving ergosterol, (22E)-ergosta-5,7,22-trien-3-beta-ol, a sterol found in ergot, yeast and moulds. It is the most important of the D provitamins and is converted to vitamin D2 on irradiation with UV light.	tmpzr1t_l9r_go_relaxed.owl	ergosterol metabolism													biological_process											owl:Class	
GO:0016128	biolink:NamedThing	phytosteroid metabolic process	The chemical reactions and pathways involving phytosteroids, steroids of higher plants that differ from animal steroids in having substitutions at C24 and/or a double bond at C22. Phytosteroids are so named because they occur in higher plants; some, notably ergosterol, are also found in fungi.	tmpzr1t_l9r_go_relaxed.owl	phytosteroid metabolism													biological_process											owl:Class	
GO:0016257	biolink:NamedThing	N-glycan processing to secreted and cell-surface N-glycans	The modification of high-mannose (Man9-Asn) N-glycans by mannosyl-oligosaccharide 1,2-alpha-mannosidase. This may result in Man8GlcNAc2-Asn N-glycans (which in yeast may be subsequently modified by the addition of further mannose residues) or Man5GlcNAc2-Asn N-glycans that are substrates for further diversification in the Golgi apparatus.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0006491	biolink:NamedThing	N-glycan processing	The conversion of N-linked glycan (N = nitrogen) structures from the initially transferred oligosaccharide to a mature form, by the actions of glycosidases and glycosyltransferases. The early processing steps are conserved and play roles in glycoprotein folding and trafficking.	tmpzr1t_l9r_go_relaxed.owl	glycoprotein trimming involved in glycoprotein maturation|N-linked glycoprotein maturation											GO:0006492		biological_process											owl:Class	
GO:0034781	biolink:NamedThing	N-cyclohexylformamide amidohydrolase activity	Catalysis of the reaction: N-cyclohexylformamide + OH- = cyclohexylamine + formate.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r1030									molecular_function											owl:Class	
GO:2000438	biolink:NamedThing	negative regulation of monocyte extravasation	Any process that stops, prevents or reduces the frequency, rate or extent of monocyte extravasation.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-03-04T10:24:44Z					biological_process											owl:Class	
GO:0080140	biolink:NamedThing	regulation of jasmonic acid metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving jasmonic acid.	tmpzr1t_l9r_go_relaxed.owl								dhl	2009-05-19T04:24:55Z					biological_process											owl:Class	
GO:0019217	biolink:NamedThing	regulation of fatty acid metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving fatty acids.	tmpzr1t_l9r_go_relaxed.owl	regulation of fatty acid metabolism											GO:0006632		biological_process											owl:Class	
GO:1902693	biolink:NamedThing	superoxide dismutase complex	A protein complex which is capable of superoxide dismutase activity.	tmpzr1t_l9r_go_relaxed.owl						An example of this is SOD1 in Saccharomyces cerevisiae S288c (UniProt symbol P00445) in PMID:10026301.		bhm	2014-02-18T11:10:11Z					cellular_component											owl:Class	
GO:1990204	biolink:NamedThing	oxidoreductase complex	Any protein complex that possesses oxidoreductase activity.	tmpzr1t_l9r_go_relaxed.owl	redox complex|oxidation-reduction complex							bhm	2013-10-07T08:24:47Z					cellular_component											owl:Class	
GO:0015866	biolink:NamedThing	ADP transport	The directed movement of ADP, adenosine diphosphate, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0015711	biolink:NamedThing	organic anion transport	The directed movement of organic anions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Organic anions are atoms or small molecules with a negative charge which contain carbon in covalent linkage.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0102025	biolink:NamedThing	ABC-type thiosulfate transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + thiosulfate(out) = ADP + phosphate + thiosulfate(in).	tmpzr1t_l9r_go_relaxed.owl	thiosulfate transmembrane-transporting ATPase activity|thiosulphate ABC transporter activity|ATPase-coupled thiosulfate transmembrane transporter activity	https://github.com/geneontology/go-ontology/issues/14642			EC:7.3.2.3|MetaCyc:ABC-7-RXN|RHEA:29871							GO:0032146		molecular_function											owl:Class	
GO:0030583	biolink:NamedThing	myxococcal fruiting body development	The process whose specific outcome is the progression of the myxococcal fruiting body over time, from its formation to the mature structure. The process begins when myxococci respond to a lack of nutrients in the environment and ends when the myxococcal fruiting body is a mature structure.	tmpzr1t_l9r_go_relaxed.owl	fruiting body development in cellular response to starvation|fruiting body development in response to starvation					For example, as seen in myxobacterium.  It is not intended to describe fruiting body development as is Dictyostelium.						GO:0055084		biological_process											owl:Class	
GO:1902761	biolink:NamedThing	positive regulation of chondrocyte development	Any process that activates or increases the frequency, rate or extent of chondrocyte development.	tmpzr1t_l9r_go_relaxed.owl	activation of chondrocyte development|up regulation of chondrocyte development|upregulation of chondrocyte development|up-regulation of chondrocyte development							mr	2014-03-07T17:45:55Z					biological_process											owl:Class	
GO:1901049	biolink:NamedThing	atropine metabolic process	The chemical reactions and pathways involving atropine.	tmpzr1t_l9r_go_relaxed.owl	atropine metabolism							yaf	2012-06-28T04:51:25Z					biological_process											owl:Class	
GO:0046448	biolink:NamedThing	tropane alkaloid metabolic process	The chemical reactions and pathways involving tropane alkaloids, compounds containing the 8-methyl-8-azabicyclo(3.2.1)octane ring system.	tmpzr1t_l9r_go_relaxed.owl	tropane alkaloid metabolism													biological_process											owl:Class	
GO:0035531	biolink:NamedThing	regulation of chemokine (C-C motif) ligand 6 production	Any process that modulates the frequency, rate, or extent of production of chemokine (C-C motif) ligand 6 (CCL6).	tmpzr1t_l9r_go_relaxed.owl	regulation of CCL6 production|regulation of chemokine (C-C motif) ligand 6 secretion|chemokine (C-C motif) ligand 6 secretion							bf	2010-05-07T10:22:51Z			GO:0035535|GO:0035534		biological_process											owl:Class	
GO:1902954	biolink:NamedThing	regulation of early endosome to recycling endosome transport	Any process that modulates the frequency, rate or extent of early endosome to recycling endosome transport.	tmpzr1t_l9r_go_relaxed.owl								sjp	2014-05-02T09:06:23Z					biological_process											owl:Class	
GO:1903649	biolink:NamedThing	regulation of cytoplasmic transport	Any process that modulates the frequency, rate or extent of cytoplasmic transport.	tmpzr1t_l9r_go_relaxed.owl	regulation of cytoplasmic streaming							jl	2014-11-24T13:38:17Z					biological_process											owl:Class	
GO:0097398	biolink:NamedThing	cellular response to interleukin-17	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-17 stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to IL-17							pr	2012-10-23T13:25:43Z					biological_process											owl:Class	
GO:0097396	biolink:NamedThing	response to interleukin-17	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-17 stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to IL-17							pr	2012-10-23T13:22:28Z					biological_process											owl:Class	
GO:1905776	biolink:NamedThing	positive regulation of DNA helicase activity	Any process that activates or increases the frequency, rate or extent of ATP-dependent DNA helicase activity.	tmpzr1t_l9r_go_relaxed.owl	up regulation of ATP-dependent DNA helicase activity|up-regulation of ATP-dependent DNA helicase activity|activation of ATP-dependent DNA helicase activity|up-regulation of DNA helicase activity|positive regulation of ATP-dependent DNA helicase activity|up regulation of DNA helicase activity|activation of DNA helicase activity|upregulation of ATP-dependent DNA helicase activity|upregulation of DNA helicase activity							rb	2013-10-15T21:20:10Z			GO:1902451		biological_process											owl:Class	
GO:1905464	biolink:NamedThing	positive regulation of DNA duplex unwinding	Any process that activates or increases the frequency, rate or extent of DNA duplex unwinding.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of duplex DNA melting|up regulation of duplex DNA melting|up regulation of DNA duplex unwinding|upregulation of duplex DNA melting|activation of DNA unwinding|activation of DNA duplex unwinding|positive regulation of duplex DNA melting|upregulation of DNA duplex unwinding|up-regulation of DNA unwinding|activation of duplex DNA melting|positive regulation of DNA unwinding|up regulation of DNA unwinding|upregulation of DNA unwinding|up-regulation of DNA duplex unwinding							ans	2016-09-19T11:58:55Z					biological_process											owl:Class	
GO:0046775	biolink:NamedThing	suppression by virus of host cytokine production	Any viral process that results in the inhibition of host cell cytokine production.	tmpzr1t_l9r_go_relaxed.owl	negative regulation by virus of host cytokine production													biological_process											owl:Class	
GO:0075528	biolink:NamedThing	modulation by virus of host immune response	The process in which a virus effects a change in the host immune response.	tmpzr1t_l9r_go_relaxed.owl	regulation by virus of host immune system process							jl	2011-08-04T02:47:57Z					biological_process											owl:Class	
GO:2000098	biolink:NamedThing	negative regulation of smooth muscle cell-matrix adhesion	Any process that stops, prevents, or reduces the frequency, rate or extent of smooth muscle cell-matrix adhesion.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-09-14T04:22:22Z					biological_process											owl:Class	
GO:1901098	biolink:NamedThing	positive regulation of autophagosome maturation	Any process that activates or increases the frequency, rate or extent of autophagosome maturation.	tmpzr1t_l9r_go_relaxed.owl	up regulation of autophagosome maturation|up regulation of autophagic vacuole maturation|activation of autophagosome maturation|positive regulation of autophagosome fusion|activation of fusion of autophagosome with lysosome|up-regulation of autolysosome formation|positive regulation of autolysosome formation|activation of autophagic vacuole fusion|upregulation of amphisome-lysosome fusion|positive regulation of autophagic vacuole fusion|up-regulation of autophagic vacuole fusion|up regulation of amphisome-lysosome fusion|activation of amphisome-lysosome fusion|up-regulation of amphisome-lysosome fusion|upregulation of autolysosome formation|up regulation of autolysosome formation|up-regulation of autophagic vacuole maturation|up regulation of fusion of autophagosome with lysosome|upregulation of autophagic vacuole fusion|up-regulation of fusion of autophagosome with lysosome|positive regulation of fusion of autophagosome with lysosome|upregulation of autophagosome maturation|activation of autophagic vacuole maturation|activation of autolysosome formation|up regulation of autophagic vacuole fusion|upregulation of fusion of autophagosome with lysosome|positive regulation of amphisome-lysosome fusion|up-regulation of autophagosome maturation|upregulation of autophagic vacuole maturation							lb	2012-07-10T07:22:34Z			GO:1902454		biological_process											owl:Class	
GO:1901096	biolink:NamedThing	regulation of autophagosome maturation	Any process that modulates the frequency, rate or extent of autophagosome maturation.	tmpzr1t_l9r_go_relaxed.owl	regulation of autolysosome formation|regulation of fusion of autophagosome with lysosome|regulation of amphisome-lysosome fusion|regulation of autophagosome fusion|regulation of autophagic vacuole fusion							lb	2012-07-10T07:22:01Z			GO:1902452		biological_process											owl:Class	
GO:0015014	biolink:NamedThing	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process	The chemical reactions and pathways resulting in the formation of polysaccharide chain component of heparan sulfate proteoglycan.	tmpzr1t_l9r_go_relaxed.owl	heparan sulphate proteoglycan biosynthesis, polysaccharide chain biosynthetic process|heparan sulfate proteoglycan formation, polysaccharide chain formation|heparan sulphate proteoglycan biosynthesis, polysaccharide chain biosynthesis|heparan sulfate proteoglycan anabolism, polysaccharide chain anabolism|heparan sulfate proteoglycan formation, polysaccharide chain biosynthesis|heparan sulfate proteoglycan synthesis, polysaccharide chain synthesis|heparan sulfate proteoglycan chain elongation|heparin proteoglycan biosynthetic process, polysaccharide chain biosynthetic process													biological_process											owl:Class	
GO:0033692	biolink:NamedThing	cellular polysaccharide biosynthetic process	The chemical reactions and pathways resulting in the formation of polysaccharides, polymers of many (typically more than 10) monosaccharide residues linked glycosidically, occurring at the level of an individual cell.	tmpzr1t_l9r_go_relaxed.owl	cellular glycan biosynthetic process|cellular polysaccharide anabolism|cellular polysaccharide synthesis|cellular polysaccharide biosynthesis|cellular polysaccharide formation|cellular glycan biosynthesis													biological_process											owl:Class	
GO:0072141	biolink:NamedThing	renal interstitial fibroblast development	The process whose specific outcome is the progression of a renal interstitial fibroblast over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl	kidney interstitial cell development							mah	2010-02-24T01:39:05Z					biological_process											owl:Class	
GO:1905341	biolink:NamedThing	negative regulation of protein localization to kinetochore	Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to kinetochore.	tmpzr1t_l9r_go_relaxed.owl	down regulation of protein localization to kinetochore|inhibition of protein localization to kinetochore|inhibition of condensin localization to kinetochore|down-regulation of protein localisation to kinetochore|down regulation of protein localisation to kinetochore|inhibition of protein localisation to kinetochore|negative regulation of protein localisation to kinetochore|downregulation of protein localization to kinetochore|down regulation of condensin localization to kinetochore|downregulation of protein localisation to kinetochore|downregulation of condensin localization to kinetochore|down-regulation of protein localization to kinetochore|down-regulation of condensin localization to kinetochore|negative regulation of condensin localization to kinetochore					Q9H211 in Human in PMID:22581055		es	2016-07-27T15:26:44Z					biological_process											owl:Class	
GO:0048523	biolink:NamedThing	negative regulation of cellular process	Any process that stops, prevents, or reduces the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.	tmpzr1t_l9r_go_relaxed.owl	downregulation of cellular process|down regulation of cellular process|inhibition of cellular process|down-regulation of cellular process|negative regulation of cellular physiological process											GO:0051243		biological_process											owl:Class	
GO:1904402	biolink:NamedThing	response to nocodazole	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nocodazole stimulus.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-06-23T21:10:45Z					biological_process											owl:Class	
GO:1901654	biolink:NamedThing	response to ketone	A response that results in a state of tolerance to ketone.	tmpzr1t_l9r_go_relaxed.owl	process resulting in tolerance to ketone							pr	2012-11-20T10:55:47Z			GO:1990369		biological_process											owl:Class	
GO:1901680	biolink:NamedThing	sulfur-containing amino acid secondary active transmembrane transporter activity	Enables the transfer of sulfur-containing amino acid from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters.	tmpzr1t_l9r_go_relaxed.owl								pr	2012-11-22T16:16:48Z					molecular_function											owl:Class	
GO:0000099	biolink:NamedThing	sulfur amino acid transmembrane transporter activity	Enables the transfer of sulfur amino acids from one side of a membrane to the other. Sulphur amino acids contain sulfur in the form of cystine, methionine or their derivatives.	tmpzr1t_l9r_go_relaxed.owl	sulphur amino acid transmembrane transporter activity|sulphur amino acid transporter activity|sulfur amino acid transporter activity													molecular_function											owl:Class	
GO:0044878	biolink:NamedThing	mitotic cytokinesis checkpoint signaling	A signaling process that contributes to a mitotic cell cycle checkpoint that detects a defect in cytokinesis and prevents further rounds of nuclear division until cytokinesis is completed.	tmpzr1t_l9r_go_relaxed.owl	signal transduction involved in mitotic cytokinesis checkpoint|signalling cascade involved in mitotic cytokinesis checkpoint|signaling pathway involved in mitotic cytokinesis checkpoint|cytokinesis after mitosis checkpoint|defective cytokinesis checkpoint|mitotic cytokinesis checkpoint|signalling pathway involved in mitotic cytokinesis checkpoint	https://github.com/geneontology/go-ontology/issues/20935						jl	2015-01-13T15:30:23Z			GO:1903820		biological_process											owl:Class	
GO:0010972	biolink:NamedThing	negative regulation of G2/M transition of mitotic cell cycle	Any signalling pathway that decreases or inhibits the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to M phase of the mitotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of mitotic entry							tb	2009-06-01T10:18:29Z					biological_process											owl:Class	
GO:0047599	biolink:NamedThing	8-oxocoformycin reductase activity	Catalysis of the reaction: coformycin + NADP(+) = 8-oxocoformycin + 2 H(+) + NADPH.	tmpzr1t_l9r_go_relaxed.owl	8-ketodeoxycoformycin reductase activity|coformycin:NADP+ 8-oxidoreductase activity				RHEA:23168|MetaCyc:8-OXOCOFORMYCIN-REDUCTASE-RXN|KEGG_REACTION:R03667|EC:1.1.1.235									molecular_function											owl:Class	
GO:0016879	biolink:NamedThing	ligase activity, forming carbon-nitrogen bonds	Catalysis of the joining of two molecules, or two groups within a single molecule, via a carbon-nitrogen bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.	tmpzr1t_l9r_go_relaxed.owl	other carbon-nitrogen ligase activity				EC:6.3.-.-									molecular_function											owl:Class	
GO:0000952	biolink:NamedThing	aromatic amino acid family catabolic process to carboxylic acid via Ehrlich pathway	The chemical reactions and pathways involving the catabolism of amino acids to produce carboxylic acids with one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. When an aromatic family amino acid, phenylalanine, tyrosine, or tryptophan, is used as the substrate, 2-phenylethanoate, 4-hydroxyphenylethanoate, or 2-(Indol-3-yl)-ethanoate, respectively, is produced. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of carboxylic acids, sometimes collectively referred to as fusel acids. Depending on the redox state of the cells, alcohol derivatives may be produced instead of carboxylic acids.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0000948	biolink:NamedThing	amino acid catabolic process to carboxylic acid via Ehrlich pathway	The chemical reactions and pathways involving the catabolism of amino acids to produce carboxylic acids with one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of carboxylic acids, sometimes collectively referred to as fusel acids. Depending on the redox state of the cells, alcohol derivatives may be produced instead of carboxylic acids.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0006964	biolink:NamedThing	positive regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria	Any process that activates or increases the frequency, rate, or extent of biosynthesis of antibacterial peptides active against Gram-negative bacteria.	tmpzr1t_l9r_go_relaxed.owl	anti-Gram-negative bacterial polypeptide induction|anti-Gram-negative bacterial peptide induction|stimulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria|up regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria|up-regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria|upregulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria|activation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria													biological_process											owl:Class	
GO:1902103	biolink:NamedThing	negative regulation of metaphase/anaphase transition of meiotic cell cycle	Any process that stops, prevents or reduces the frequency, rate or extent of metaphase/anaphase transition of meiotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl	down regulation of metaphase/anaphase transition of meiotic cell cycle|down-regulation of metaphase/anaphase transition of meiotic cell cycle|down-regulation of meiotic metaphase/anaphase transition|downregulation of metaphase/anaphase transition of meiotic cell cycle|inhibition of metaphase/anaphase transition of meiotic cell cycle|down regulation of meiotic metaphase/anaphase transition|downregulation of meiotic metaphase/anaphase transition|inhibition of meiotic metaphase/anaphase transition|negative regulation of meiotic metaphase/anaphase transition							jl	2013-05-02T12:45:43Z					biological_process											owl:Class	
GO:1905133	biolink:NamedThing	negative regulation of meiotic chromosome separation	Any process that stops, prevents or reduces the frequency, rate or extent of meiotic chromosome separation.	tmpzr1t_l9r_go_relaxed.owl	down regulation of meiotic chromosome resolution|negative regulation of chromosome separation during meiosis|down-regulation of chromosome separation during meiosis|inhibition of chromosome separation during meiosis|downregulation of meiotic chromosome separation|downregulation of chromosome separation during meiosis|inhibition of meiotic chromosome resolution|inhibition of meiotic chromosome separation|negative regulation of meiotic chromosome resolution|down regulation of meiotic chromosome separation|down-regulation of meiotic chromosome resolution|down-regulation of meiotic chromosome separation|down regulation of chromosome separation during meiosis|downregulation of meiotic chromosome resolution							dph	2016-04-12T17:46:37Z					biological_process											owl:Class	
GO:0005983	biolink:NamedThing	starch catabolic process	The chemical reactions and pathways resulting in the breakdown of starch, the most important reserve polysaccharide in plants.	tmpzr1t_l9r_go_relaxed.owl	starch catabolism|starch breakdown|starch degradation				MetaCyc:PWY-842									biological_process											owl:Class	
GO:0044247	biolink:NamedThing	cellular polysaccharide catabolic process	The chemical reactions and pathways resulting in the breakdown of polysaccharides, polymers of many (typically more than 10) monosaccharide residues linked glycosidically, as carried out by individual cells.	tmpzr1t_l9r_go_relaxed.owl	cellular polysaccharide breakdown|cellular polysaccharide catabolism|cellular polysaccharide degradation													biological_process											owl:Class	
GO:1990318	biolink:NamedThing	collagen type XIX trimer	A collagen homotrimer of alpha1(XIX) chains; type XIX collagen triple helices localize to basement membrane zones in differentiating muscle cells.	tmpzr1t_l9r_go_relaxed.owl								bhm	2014-03-14T16:05:57Z					cellular_component											owl:Class	
GO:0098651	biolink:NamedThing	basement membrane collagen trimer	Any collagen timer that is part of a basement membrane.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0048235	biolink:NamedThing	pollen sperm cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a haploid sperm cell within the plant gametophyte.	tmpzr1t_l9r_go_relaxed.owl	sperm cell differentiation|male gamete generation|male gametophyte sperm cell differentiation											GO:0048234		biological_process											owl:Class	
GO:0031405	biolink:NamedThing	lipoic acid binding	Binding to lipoic acid, 1,2-dithiolane-3-pentanoic acid.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0097159	biolink:NamedThing	organic cyclic compound binding	Binding to an organic cyclic compound, any molecular entity that contains carbon arranged in a cyclic molecular structure.	tmpzr1t_l9r_go_relaxed.owl								pr	2011-09-23T02:31:01Z					molecular_function											owl:Class	
GO:0033507	biolink:NamedThing	glucosinolate biosynthetic process from phenylalanine	The chemical reactions and pathways resulting in the formation of glucosinolates from other compounds including phenylalanine.	tmpzr1t_l9r_go_relaxed.owl	glucosinolate formation from phenylalanine|glucosinolate anabolism from phenylalanine|glucosinolate biosynthesis from phenylalanine|glucosinolate synthesis from phenylalanine				MetaCyc:PWY-2821									biological_process											owl:Class	
GO:0019761	biolink:NamedThing	glucosinolate biosynthetic process	The chemical reactions and pathways resulting in the formation of glucosinolates, substituted thioglucosides found in rapeseed products and related cruciferae.	tmpzr1t_l9r_go_relaxed.owl	glucosinolate formation|glucosinolate anabolism|glucosinolate synthesis|glucosinolate biosynthesis													biological_process											owl:Class	
GO:0004075	biolink:NamedThing	biotin carboxylase activity	Catalysis of the reaction: ATP + biotin-carboxyl-carrier protein + CO2 = ADP + phosphate + carboxybiotin-carboxyl-carrier protein.	tmpzr1t_l9r_go_relaxed.owl	biotin carboxylase (component of acetyl CoA carboxylase) activity|biotin-carboxyl-carrier-protein:carbon-dioxide ligase (ADP-forming) activity				EC:6.3.4.14|RHEA:13501|MetaCyc:BIOTIN-CARBOXYL-RXN									molecular_function											owl:Class	
GO:0009102	biolink:NamedThing	biotin biosynthetic process	The chemical reactions and pathways resulting in the formation of biotin, cis-tetrahydro-2-oxothieno(3,4-d)imidazoline-4-valeric acid.	tmpzr1t_l9r_go_relaxed.owl	biotin synthesis|biotin anabolism|vitamin H biosynthesis|vitamin B7 biosynthesis|vitamin B7 biosynthetic process|biotin formation|biotin biosynthesis|vitamin H biosynthetic process				MetaCyc:BIOTIN-SYNTHESIS-PWY									biological_process											owl:Class	
GO:0017166	biolink:NamedThing	vinculin binding	Binding to vinculin, a protein found in muscle, fibroblasts, and epithelial cells that binds actin and appears to mediate attachment of actin filaments to integral proteins of the plasma membrane.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0008092	biolink:NamedThing	cytoskeletal protein binding	Binding to a protein component of a cytoskeleton (actin, microtubule, or intermediate filament cytoskeleton).	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0035265	biolink:NamedThing	organ growth	The increase in size or mass of an organ. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that function together as to perform a specific function.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0003824	biolink:NamedThing	catalytic activity	Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.	tmpzr1t_l9r_go_relaxed.owl	enzyme activity				Wikipedia:Enzyme									molecular_function											owl:Class	
GO:1903592	biolink:NamedThing	positive regulation of lysozyme activity	Any process that activates or increases the frequency, rate or extent of lysozyme activity.	tmpzr1t_l9r_go_relaxed.owl	activation of muramidase activity|up-regulation of peptidoglycan N-acetylmuramoylhydrolase activity|up-regulation of mucopeptide glucohydrolase activity|upregulation of mucopeptide glucohydrolase activity|up-regulation of mucopeptide N-acetylmuramoylhydrolase activity|positive regulation of globulin G1|up-regulation of globulin G1|up-regulation of N,O-diacetylmuramidase activity|activation of mucopeptide N-acetylmuramoylhydrolase activity|activation of L-7001|activation of 1,4-N-acetylmuramidase activity|activation of PR1-lysozyme|upregulation of N,O-diacetylmuramidase activity|up-regulation of lysozyme activity|upregulation of globulin G1|up regulation of N,O-diacetylmuramidase activity|up-regulation of muramidase activity|up-regulation of L-7001|upregulation of lysozyme g|upregulation of L-7001|activation of globulin G1|up-regulation of 1,4-N-acetylmuramidase activity|positive regulation of N,O-diacetylmuramidase activity|positive regulation of globulin G|up regulation of globulin G|positive regulation of lysozyme g|up regulation of mucopeptide glucohydrolase activity|upregulation of muramidase activity|up regulation of 1,4-N-acetylmuramidase activity|positive regulation of L-7001|upregulation of 1,4-N-acetylmuramidase activity|positive regulation of 1,4-N-acetylmuramidase activity|activation of lysozyme activity|upregulation of PR1-lysozyme|up regulation of muramidase activity|activation of lysozyme g|upregulation of peptidoglycan N-acetylmuramoylhydrolase activity|activation of peptidoglycan N-acetylmuramoylhydrolase activity|activation of N,O-diacetylmuramidase activity|upregulation of globulin G|upregulation of lysozyme activity|up regulation of globulin G1|up-regulation of globulin G|up regulation of mucopeptide N-acetylmuramoylhydrolase activity|up regulation of lysozyme g|up-regulation of lysozyme g|positive regulation of mucopeptide glucohydrolase activity|up regulation of L-7001|positive regulation of PR1-lysozyme|positive regulation of mucopeptide N-acetylmuramoylhydrolase activity|up regulation of lysozyme activity|upregulation of mucopeptide N-acetylmuramoylhydrolase activity|activation of globulin G|up regulation of PR1-lysozyme|positive regulation of peptidoglycan N-acetylmuramoylhydrolase activity|up-regulation of PR1-lysozyme|activation of mucopeptide glucohydrolase activity|positive regulation of muramidase activity|up regulation of peptidoglycan N-acetylmuramoylhydrolase activity							mr	2014-11-05T21:41:39Z					biological_process											owl:Class	
GO:0051345	biolink:NamedThing	positive regulation of hydrolase activity	Any process that activates or increases the frequency, rate or extent of hydrolase activity, the catalysis of the hydrolysis of various bonds.	tmpzr1t_l9r_go_relaxed.owl	hydrolase activator|upregulation of hydrolase activity|up-regulation of hydrolase activity|up regulation of hydrolase activity|stimulation of hydrolase activity|activation of hydrolase activity													biological_process											owl:Class	
GO:1905510	biolink:NamedThing	negative regulation of myosin II filament assembly	Any process that stops, prevents or reduces the frequency, rate or extent of myosin II filament assembly.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of myosin II filament assembly|negative regulation of myosin II polymerization|down regulation of myosin II polymerization|down-regulation of myosin II polymerization|down regulation of myosin II filament assembly|downregulation of myosin II polymerization|inhibition of myosin II polymerization|downregulation of myosin II filament assembly|inhibition of myosin II filament assembly					positive regulation / down regulation of the formation of a bipolar filament composed of myosin II molecules		pf	2016-09-28T13:47:56Z					biological_process											owl:Class	
GO:0034875	biolink:NamedThing	caffeine oxidase activity	Catalysis of the reaction: caffeine + O2 + 2 H+ + 2 e- = 1,3,7-trimethyluric acid + H2O.	tmpzr1t_l9r_go_relaxed.owl					EC:1.17.5.2|RHEA:47148|UM-BBD_reactionID:r1321									molecular_function											owl:Class	
GO:0033695	biolink:NamedThing	oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which a CH2 group acts as a hydrogen or electron donor and reduces a quinone or similar acceptor molecule.	tmpzr1t_l9r_go_relaxed.owl					EC:1.17.5.-									molecular_function											owl:Class	
GO:0060180	biolink:NamedThing	female mating behavior	The specific behavior of a female organism that is associated with reproduction.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0007617	biolink:NamedThing	mating behavior	The behavioral interactions between organisms for the purpose of mating, or sexual reproduction resulting in the formation of zygotes.	tmpzr1t_l9r_go_relaxed.owl	mating behaviour				Wikipedia:Mating_behaviour									biological_process											owl:Class	
GO:0002635	biolink:NamedThing	negative regulation of germinal center formation	Any process that stops, prevents, or reduces the frequency, rate, or extent of germinal center formation.	tmpzr1t_l9r_go_relaxed.owl	inhibition of germinal center formation|downregulation of germinal center formation|down-regulation of germinal center formation|down regulation of germinal center formation													biological_process											owl:Class	
GO:0032743	biolink:NamedThing	positive regulation of interleukin-2 production	Any process that activates or increases the frequency, rate, or extent of interleukin-2 production.	tmpzr1t_l9r_go_relaxed.owl	activation of interleukin-2 production|stimulation of interleukin-2 production|upregulation of interleukin-2 production|up regulation of interleukin-2 production|up-regulation of interleukin-2 production|positive regulation of interleukin-2 biosynthetic process|positive regulation of IL-2 production|positive regulation of interleukin-2 secretion											GO:1900042|GO:0045086		biological_process											owl:Class	
GO:0001819	biolink:NamedThing	positive regulation of cytokine production	Any process that activates or increases the frequency, rate or extent of production of a cytokine.	tmpzr1t_l9r_go_relaxed.owl	activation of cytokine production|upregulation of cytokine production|positive regulation of cytokine biosynthetic process|up-regulation of cytokine production|positive regulation of cytokine secretion|stimulation of cytokine production|up regulation of cytokine production											GO:0050715|GO:0042108		biological_process											owl:Class	
GO:0097184	biolink:NamedThing	response to azide	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an azide stimulus.	tmpzr1t_l9r_go_relaxed.owl								pr	2011-11-16T10:00:58Z					biological_process											owl:Class	
GO:1901698	biolink:NamedThing	response to nitrogen compound	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrogen compound stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to nitrogen molecular entity							pr	2012-12-13T15:06:08Z					biological_process											owl:Class	
GO:1900332	biolink:NamedThing	positive regulation of methane biosynthetic process from trimethylamine	Any process that activates or increases the frequency, rate or extent of methane biosynthetic process from trimethylamine.	tmpzr1t_l9r_go_relaxed.owl	up regulation of methane biosynthetic process from trimethylamine|up-regulation of methane biosynthetic process from trimethylamine|activation of methane biosynthetic process from trimethylamine|upregulation of methane biosynthetic process from trimethylamine							tt	2012-04-06T01:53:20Z					biological_process											owl:Class	
GO:1900330	biolink:NamedThing	regulation of methane biosynthetic process from trimethylamine	Any process that modulates the frequency, rate or extent of methane biosynthetic process from trimethylamine.	tmpzr1t_l9r_go_relaxed.owl								tt	2012-04-06T01:53:03Z					biological_process											owl:Class	
GO:0043169	biolink:NamedThing	cation binding	Binding to a cation, a charged atom or group of atoms with a net positive charge.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0043167	biolink:NamedThing	ion binding	Binding to an ion, a charged atoms or groups of atoms.	tmpzr1t_l9r_go_relaxed.owl	atom binding													molecular_function											owl:Class	
GO:0036403	biolink:NamedThing	arachidonate 8(S)-lipoxygenase activity	Catalysis of the reaction: arachidonate + O(2) = (5Z,8S,9E,11Z,14Z)-8-hydroperoxyicosa-5,9,11,14-tetraenoate.	tmpzr1t_l9r_go_relaxed.owl	8(S)-lipoxygenase activity|8-lipoxygenase (S-type)				RHEA:38675|KEGG_REACTION:R07053	This activity produces the S-enantiomer of HPETE, 8(S)-HPETE. For the reaction producing the S-enantiomer, see GO:0047677.		bf	2013-08-14T11:48:46Z					molecular_function											owl:Class	
GO:0033198	biolink:NamedThing	response to ATP	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ATP (adenosine 5'-triphosphate) stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to adenosine triphosphate|response to adenosine 5'-triphosphate													biological_process											owl:Class	
GO:0061583	biolink:NamedThing	colon epithelial cell chemotaxis	The directed movement of a colon epithelial cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).	tmpzr1t_l9r_go_relaxed.owl								dph	2013-12-23T07:46:57Z					biological_process											owl:Class	
GO:0061580	biolink:NamedThing	colon epithelial cell migration	The orderly movement of a colonic epithelial cell from one site to another, often during the development of a multicellular organism.	tmpzr1t_l9r_go_relaxed.owl								dph	2013-12-23T07:26:54Z					biological_process											owl:Class	
GO:0035726	biolink:NamedThing	common myeloid progenitor cell proliferation	The multiplication or reproduction of common myeloid progenitor cells, resulting in the expansion of a cell population. A common myeloid progenitor cell is a progenitor cell committed to the myeloid lineage.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-03-10T02:57:19Z					biological_process											owl:Class	
GO:0106014	biolink:NamedThing	regulation of inflammatory response to wounding	Any process that modulates the frequency, rate or extent of the inflammatory response to wounding.	tmpzr1t_l9r_go_relaxed.owl								hjd	2017-04-28T20:03:14Z					biological_process											owl:Class	
GO:1901403	biolink:NamedThing	positive regulation of tetrapyrrole metabolic process	Any process that activates or increases the frequency, rate or extent of tetrapyrrole metabolic process.	tmpzr1t_l9r_go_relaxed.owl	activation of tetrapyrrole metabolism|positive regulation of tetrapyrrole metabolism|upregulation of tetrapyrrole metabolic process|up-regulation of tetrapyrrole metabolism|up regulation of tetrapyrrole metabolism|up-regulation of tetrapyrrole metabolic process|upregulation of tetrapyrrole metabolism|activation of tetrapyrrole metabolic process|up regulation of tetrapyrrole metabolic process							tt	2012-10-01T14:35:29Z					biological_process											owl:Class	
GO:0140022	biolink:NamedThing	cnida	A giant secretory organelle that comprises a bulb-shape capsule containing a coiled hollow tubule structure attached to it. A cnida defines the phylum Cnidaria.	tmpzr1t_l9r_go_relaxed.owl	cnidae (plural)							cjm	2017-04-12T15:12:20Z					cellular_component											owl:Class	
GO:2000284	biolink:NamedThing	positive regulation of cellular amino acid biosynthetic process	Any process that activates or increases the frequency, rate or extent of cellular amino acid biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of cellular amino acid formation|positive regulation of cellular amino acid synthesis|positive regulation of amino acid biosynthetic process|positive regulation of cellular amino acid biosynthesis|positive regulation of cellular amino acid anabolism							vw	2010-12-10T11:54:27Z					biological_process											owl:Class	
GO:0045764	biolink:NamedThing	positive regulation of cellular amino acid metabolic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving amino acid.	tmpzr1t_l9r_go_relaxed.owl	activation of amino acid metabolic process|up regulation of amino acid metabolic process|stimulation of amino acid metabolic process|up-regulation of amino acid metabolic process|positive regulation of amino acid metabolism|upregulation of amino acid metabolic process													biological_process											owl:Class	
GO:0036277	biolink:NamedThing	response to anticonvulsant	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an anticonvulsant stimulus, a drug used to prevent seizures or reduce their severity.	tmpzr1t_l9r_go_relaxed.owl						Note that this term is in the subset of terms that should not be used for direct manual annotation of gene products. It was created to be used for cross-referencing by other ontologies. Direct annotations to this term may be amended during annotation QC.		bf	2012-07-09T02:40:12Z					biological_process											owl:Class	
GO:0042221	biolink:NamedThing	response to chemical	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to chemical substance|response to chemical stimulus					Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.								biological_process											owl:Class	
GO:0033642	biolink:NamedThing	modulation by symbiont of host response to gravitational stimulus	Any process in which an organism modulates a change in state or activity of a host cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gravitational stimulus. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	response to gravitational stimulus													biological_process											owl:Class	
GO:0033635	biolink:NamedThing	modulation by symbiont of host response to abiotic stimulus	Any process in which an organism modulates a change in the state or activity of a host cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abiotic (non-living) stimulus. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0031655	biolink:NamedThing	negative regulation of heat dissipation	Any process that stops, prevents, or reduces the rate or extent of heat dissipation.	tmpzr1t_l9r_go_relaxed.owl	inhibition of heat dissipation|down-regulation of heat dissipation|downregulation of heat dissipation|down regulation of heat dissipation													biological_process											owl:Class	
GO:0030100	biolink:NamedThing	regulation of endocytosis	Any process that modulates the frequency, rate or extent of endocytosis.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0060627	biolink:NamedThing	regulation of vesicle-mediated transport	Any process that modulates the rate, frequency, or extent of vesicle-mediated transport, the directed movement of substances, either within a vesicle or in the vesicle membrane, into, out of or within a cell.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-05-18T02:29:43Z					biological_process											owl:Class	
GO:0032353	biolink:NamedThing	negative regulation of hormone biosynthetic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hormones.	tmpzr1t_l9r_go_relaxed.owl	down regulation of hormone biosynthetic process|down-regulation of hormone biosynthetic process|inhibition of hormone biosynthetic process|downregulation of hormone biosynthetic process													biological_process											owl:Class	
GO:0070901	biolink:NamedThing	mitochondrial tRNA methylation	The posttranscriptional addition of methyl groups to specific residues in a mitochondrial tRNA molecule.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-09-02T04:08:00Z					biological_process											owl:Class	
GO:0070900	biolink:NamedThing	mitochondrial tRNA modification	The covalent alteration of one or more nucleotides within a mitochondrial tRNA molecule to produce a mitochondrial tRNA molecule with a sequence that differs from that coded genetically.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-09-02T03:16:53Z					biological_process											owl:Class	
GO:0140023	biolink:NamedThing	tRNA adenosine deamination to inosine	The removal of an amine group from an adenosine to produce inosine within a tRNA molecule.	tmpzr1t_l9r_go_relaxed.owl	A-to-I tRNA editing							pg	2017-04-26T05:56:51Z					biological_process											owl:Class	
GO:0006400	biolink:NamedThing	tRNA modification	The covalent alteration of one or more nucleotides within a tRNA molecule to produce a tRNA molecule with a sequence that differs from that coded genetically.	tmpzr1t_l9r_go_relaxed.owl	tRNA editing					The term 'RNA editing' (GO:0016547) was merged into 'RNA modification' (GO:0009451) on the basis of statements in the preface of Modification and Editing of RNA (ISBN:1555811337) that there is no clear distinction between modification and editing. Parallel changes were made for substrate (e.g. tRNA, rRNA, etc.) specific child terms of 'RNA editing'.						GO:0016549		biological_process											owl:Class	
GO:0010470	biolink:NamedThing	regulation of gastrulation	Any process that modulates the rate or extent of gastrulation. Gastrulation is the complex and coordinated series of cellular movements that occurs at the end of cleavage during embryonic development of most animals.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:2000239	biolink:NamedThing	negative regulation of tRNA export from nucleus	Any process that stops, prevents, or reduces the frequency, rate or extent of tRNA export from nucleus.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of tRNA export out of nucleus|negative regulation of tRNA-nucleus export|negative regulation of tRNA export from cell nucleus|negative regulation of tRNA transport from nucleus to cytoplasm							mah	2010-11-10T12:39:36Z					biological_process											owl:Class	
GO:2000198	biolink:NamedThing	negative regulation of ribonucleoprotein complex localization	Any process that stops, prevents, or reduces the frequency, rate or extent of ribonucleoprotein complex localization.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of RNP localization|negative regulation of cellular ribonucleoprotein complex localization|negative regulation of establishment and maintenance of ribonucleoprotein complex localization|negative regulation of ribonucleoprotein complex localisation							mah	2010-10-26T10:35:52Z					biological_process											owl:Class	
GO:1902324	biolink:NamedThing	positive regulation of methyl-branched fatty acid biosynthetic process	Any process that activates or increases the frequency, rate or extent of methyl-branched fatty acid biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	upregulation of methyl-branched fatty acid biosynthetic process|activation of methyl-branched fatty acid biosynthesis|up-regulation of methyl-branched fatty acid synthesis|upregulation of methyl-branched fatty acid formation|upregulation of methyl-branched fatty acid biosynthesis|activation of methyl-branched fatty acid formation|up-regulation of methyl-branched fatty acid biosynthesis|activation of methyl-branched fatty acid anabolism|positive regulation of methyl-branched fatty acid synthesis|positive regulation of methyl-branched fatty acid formation|up regulation of methyl-branched fatty acid synthesis|upregulation of methyl-branched fatty acid synthesis|up-regulation of methyl-branched fatty acid anabolism|up regulation of methyl-branched fatty acid biosynthesis|positive regulation of methyl-branched fatty acid anabolism|up regulation of methyl-branched fatty acid anabolism|up-regulation of methyl-branched fatty acid formation|up regulation of methyl-branched fatty acid formation|up-regulation of methyl-branched fatty acid biosynthetic process|positive regulation of methyl-branched fatty acid biosynthesis|up regulation of methyl-branched fatty acid biosynthetic process|upregulation of methyl-branched fatty acid anabolism|activation of methyl-branched fatty acid synthesis|activation of methyl-branched fatty acid biosynthetic process							kmv	2013-07-24T20:15:31Z					biological_process											owl:Class	
GO:0051106	biolink:NamedThing	positive regulation of DNA ligation	Any process that activates or increases the frequency, rate or extent of DNA ligation, the re-formation of a broken phosphodiester bond in the DNA backbone, carried out by DNA ligase.	tmpzr1t_l9r_go_relaxed.owl	activation of DNA ligation|up regulation of DNA ligation|stimulation of DNA ligation|upregulation of DNA ligation|up-regulation of DNA ligation													biological_process											owl:Class	
GO:0051054	biolink:NamedThing	positive regulation of DNA metabolic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving DNA.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of DNA metabolic process|upregulation of DNA metabolic process|stimulation of DNA metabolic process|positive regulation of DNA metabolism|activation of DNA metabolic process|up regulation of DNA metabolic process													biological_process											owl:Class	
GO:1903363	biolink:NamedThing	negative regulation of cellular protein catabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of cellular protein catabolic process.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of cellular protein degradation|downregulation of cellular protein degradation|negative regulation of cyclin catabolic process|down regulation of cellular protein catabolism|down regulation of cellular protein catabolic process|inhibition of cellular protein catabolic process|downregulation of cellular protein catabolic process|down-regulation of cellular protein breakdown|inhibition of cellular protein breakdown|inhibition of cellular protein catabolism|negative regulation of cellular protein breakdown|negative regulation of degradation of cyclin|down regulation of cellular protein breakdown|negative regulation of cellular protein catabolism|downregulation of cellular protein breakdown|down-regulation of cellular protein catabolism|downregulation of cellular protein catabolism|negative regulation of cyclin breakdown|negative regulation of cyclin degradation|down regulation of cellular protein degradation|inhibition of cellular protein degradation|down-regulation of cellular protein degradation|down-regulation of cellular protein catabolic process|negative regulation of cyclin catabolism							kmv	2014-08-21T15:05:53Z			GO:2000599		biological_process											owl:Class	
GO:0032269	biolink:NamedThing	negative regulation of cellular protein metabolic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving a protein, occurring at the level of an individual cell.	tmpzr1t_l9r_go_relaxed.owl	inhibition of cellular protein metabolic process|down-regulation of cellular protein metabolic process|downregulation of cellular protein metabolic process|down regulation of cellular protein metabolic process|negative regulation of cellular protein metabolism													biological_process											owl:Class	
GO:0046498	biolink:NamedThing	S-adenosylhomocysteine metabolic process	The chemical reactions and pathways involving S-adenosylhomocysteine; the L-enantiomer is formed from S-adenosylmethionine and is a strong inhibitor of S-adenosylmethionine-mediated methylation reactions. It can be cleaved to form adenosine and homocysteine.	tmpzr1t_l9r_go_relaxed.owl	S-adenosylhomocysteine metabolism													biological_process											owl:Class	
GO:0006575	biolink:NamedThing	cellular modified amino acid metabolic process	The chemical reactions and pathways involving compounds derived from amino acids, organic acids containing one or more amino substituents.	tmpzr1t_l9r_go_relaxed.owl	cellular amino acid derivative metabolic process|modified amino acid metabolic process|cellular modified amino acid metabolism|amino acid derivative metabolic process|modified amino acid metabolism|cellular amino acid derivative metabolism													biological_process											owl:Class	
GO:0044524	biolink:NamedThing	protein sulfhydration	The modification of a protein amino acid by the addition of sulfur.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-03-15T09:39:33Z					biological_process											owl:Class	
GO:1900913	biolink:NamedThing	positive regulation of olefin biosynthetic process	Any process that activates or increases the frequency, rate or extent of olefin biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	upregulation of olefin synthesis|activation of olefin biosynthesis|up-regulation of olefin biosynthesis|up-regulation of olefin formation|up regulation of olefin biosynthesis|up regulation of olefin biosynthetic process|up regulation of olefin anabolism|positive regulation of olefin formation|upregulation of olefin biosynthetic process|activation of olefin anabolism|positive regulation of olefin anabolism|up regulation of olefin synthesis|up-regulation of olefin anabolism|activation of olefin synthesis|up-regulation of olefin synthesis|upregulation of olefin biosynthesis|positive regulation of olefin synthesis|upregulation of olefin formation|positive regulation of olefin biosynthesis|up-regulation of olefin biosynthetic process|activation of olefin biosynthetic process|up regulation of olefin formation|upregulation of olefin anabolism|activation of olefin formation							tt	2012-06-13T04:20:38Z					biological_process											owl:Class	
GO:0032900	biolink:NamedThing	negative regulation of neurotrophin production	Any process that stops, prevents, or reduces the frequency, rate, or extent of production of a neurotrophin.	tmpzr1t_l9r_go_relaxed.owl	down regulation of neurotrophin production|down-regulation of neurotrophin production|inhibition of neurotrophin production|downregulation of neurotrophin production													biological_process											owl:Class	
GO:0019206	biolink:NamedThing	nucleoside kinase activity	Catalysis of the reaction: ATP + nucleoside = ADP + nucleoside monophosphate.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-110137|Reactome:R-HSA-73632|Reactome:R-HSA-74207|Reactome:R-HSA-73599|Reactome:R-HSA-109671|Reactome:R-HSA-109759|Reactome:R-HSA-109903|Reactome:R-HSA-73598|Reactome:R-HSA-110138									molecular_function											owl:Class	
GO:0019205	biolink:NamedThing	nucleobase-containing compound kinase activity	Catalysis of the transfer of a phosphate group, usually from ATP or GTP, to a nucleobase, nucleoside, nucleotide or polynucleotide substrate.	tmpzr1t_l9r_go_relaxed.owl	nucleobase, nucleoside, nucleotide kinase activity													molecular_function											owl:Class	
GO:0070233	biolink:NamedThing	negative regulation of T cell apoptotic process	Any process that stops, prevents, or reduces the frequency, rate or extent of T cell death by apoptotic process.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of T lymphocyte apoptosis|negative regulation of T-cell apoptosis|negative regulation of programmed cell death of T cells by apoptosis|down-regulation of T cell apoptosis|down regulation of T cell apoptosis|downregulation of T cell apoptosis|negative regulation of T cell apoptosis|negative regulation of T-lymphocyte apoptosis|inhibition of T cell apoptosis													biological_process											owl:Class	
GO:0070232	biolink:NamedThing	regulation of T cell apoptotic process	Any process that modulates the occurrence or rate of T cell death by apoptotic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of T lymphocyte apoptosis|regulation of T-lymphocyte apoptosis|regulation of T-cell apoptosis|regulation of programmed cell death of T cells by apoptosis|regulation of T cell apoptosis													biological_process											owl:Class	
GO:0009850	biolink:NamedThing	auxin metabolic process	The chemical reactions and pathways involving auxins, a group of plant hormones that regulate aspects of plant growth.	tmpzr1t_l9r_go_relaxed.owl	auxin metabolism													biological_process											owl:Class	
GO:0044237	biolink:NamedThing	cellular metabolic process	The chemical reactions and pathways by which individual cells transform chemical substances.	tmpzr1t_l9r_go_relaxed.owl	cellular metabolism|intermediary metabolism													biological_process											owl:Class	
GO:1902262	biolink:NamedThing	apoptotic process involved in blood vessel morphogenesis	Any apoptotic process that is involved in blood vessel morphogenesis.	tmpzr1t_l9r_go_relaxed.owl	apoptosis involved in patterning of blood vessels|programmed cell death by apoptosis involved in patterning of blood vessels|signaling (initiator) caspase activity involved in patterning of blood vessels|apoptotic program involved in patterning of blood vessels|apoptotic programmed cell death involved in patterning of blood vessels|apoptotic cell death involved in patterning of blood vessels|type I programmed cell death involved in patterning of blood vessels							dph	2013-06-25T16:16:00Z					biological_process											owl:Class	
GO:0035064	biolink:NamedThing	methylated histone binding	Binding to a histone in which a residue has been modified by methylation. Histones are any of a group of water-soluble proteins found in association with the DNA of eukaroytic chromosomes.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0140034	biolink:NamedThing	methylation-dependent protein binding	Binding to a protein upon methylation of the target protein.	tmpzr1t_l9r_go_relaxed.owl						This term should only be used when the binding is shown to require methylation of the target protein: the interaction needs to be tested with and without the PTM. The binding does not need to be at the site of methylation. It may be that the methylation causes a conformational change that allows binding of the protein to another region; this type of methylation-dependent protein binding is valid for annotation to this term.		pg	2017-05-17T15:40:02Z					molecular_function											owl:Class	
GO:0061441	biolink:NamedThing	renal artery morphogenesis	The process in which the anatomical structure of a renal artery is generated and organized. Renal arteries supply the kidneys with blood.	tmpzr1t_l9r_go_relaxed.owl								dph	2012-03-08T12:42:09Z					biological_process											owl:Class	
GO:0048844	biolink:NamedThing	artery morphogenesis	The process in which the anatomical structures of arterial blood vessels are generated and organized. Arteries are blood vessels that transport blood from the heart to the body and its organs.	tmpzr1t_l9r_go_relaxed.owl	arteriogenesis|arterial morphogenesis													biological_process											owl:Class	
GO:0102851	biolink:NamedThing	1-18:2-2-16:0-phosphatidylglycerol desaturase activity	Catalysis of the reaction: 1-18:2-2-16:0-phosphatidylglycerol + O2 + a reduced electron acceptor <=> 1-18:2-2-trans-16:1-phosphatidylglycerol + 2 H2O + an oxidized electron acceptor.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-8318|EC:1.14.19.43									molecular_function											owl:Class	
GO:0016717	biolink:NamedThing	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water	Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from each of two donors, and molecular oxygen is reduced to two molecules of water.	tmpzr1t_l9r_go_relaxed.owl					EC:1.14.19.-									molecular_function											owl:Class	
GO:0034093	biolink:NamedThing	positive regulation of maintenance of sister chromatid cohesion	Any process that increases the extent to which the association between sister chromatids of a replicated chromosome is maintained.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0034091	biolink:NamedThing	regulation of maintenance of sister chromatid cohesion	Any process that modulates the extent to which the association between sister chromatids of a replicated chromosome is maintained.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1900257	biolink:NamedThing	negative regulation of beta1-adrenergic receptor activity	Any process that stops, prevents or reduces the frequency, rate or extent of beta1-adrenergic receptor activity.	tmpzr1t_l9r_go_relaxed.owl	downregulation of beta1-adrenergic receptor activity|down-regulation of beta1-adrenergic receptor activity|down-regulation of beta1 adrenoceptor|downregulation of beta1 adrenoceptor|down regulation of beta1 adrenoceptor|negative regulation of beta1 adrenoceptor|inhibition of beta1 adrenoceptor|inhibition of beta1-adrenergic receptor activity|down regulation of beta1-adrenergic receptor activity							tb	2012-04-03T10:59:40Z					biological_process											owl:Class	
GO:0062088	biolink:NamedThing	negative regulation of vein smooth muscle contraction	Any process that decreases the frequency, rate or extent of vein smooth muscle contraction.	tmpzr1t_l9r_go_relaxed.owl								dph	2018-11-02T15:28:32Z					biological_process											owl:Class	
GO:0062086	biolink:NamedThing	regulation of vein smooth muscle contraction	Any process that modulates the frequency, rate or extent of vein smooth muscle contraction.	tmpzr1t_l9r_go_relaxed.owl								dph	2018-11-02T15:17:26Z					biological_process											owl:Class	
GO:1900666	biolink:NamedThing	positive regulation of emodin biosynthetic process	Any process that activates or increases the frequency, rate or extent of emodin biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	up regulation of emodin formation|upregulation of emodin biosynthetic process|up-regulation of emodin synthesis|up-regulation of emodin biosynthetic process|upregulation of emodin anabolism|positive regulation of emodin synthesis|up regulation of emodin biosynthetic process|activation of emodin biosynthesis|up-regulation of emodin anabolism|up regulation of emodin biosynthesis|activation of emodin formation|positive regulation of emodin biosynthesis|up regulation of emodin synthesis|upregulation of emodin biosynthesis|activation of emodin anabolism|up-regulation of emodin biosynthesis|upregulation of emodin synthesis|up-regulation of emodin formation|activation of emodin synthesis|activation of emodin biosynthetic process|positive regulation of emodin anabolism|upregulation of emodin formation|positive regulation of emodin formation|up regulation of emodin anabolism							di	2012-05-22T04:15:06Z					biological_process											owl:Class	
GO:0009190	biolink:NamedThing	cyclic nucleotide biosynthetic process	The chemical reactions and pathways resulting in the formation of a cyclic nucleotide, a nucleotide in which the phosphate group is in diester linkage to two positions on the sugar residue.	tmpzr1t_l9r_go_relaxed.owl	cyclic nucleotide anabolism|cyclic nucleotide biosynthesis|cyclic nucleotide formation|cyclic nucleotide synthesis													biological_process											owl:Class	
GO:0009187	biolink:NamedThing	cyclic nucleotide metabolic process	The chemical reactions and pathways involving a cyclic nucleotide, a nucleotide in which the phosphate group is in diester linkage to two positions on the sugar residue.	tmpzr1t_l9r_go_relaxed.owl	cyclic nucleotide metabolism													biological_process											owl:Class	
GO:0016137	biolink:NamedThing	glycoside metabolic process	The chemical reactions and pathways involving glycosides, compounds in which a glycosyl group is substituted into a hydroxyl, thiol or selenol group in another compound.	tmpzr1t_l9r_go_relaxed.owl	O-glycoside metabolism|O-glycoside metabolic process|glycoside metabolism											GO:0016140		biological_process											owl:Class	
GO:0102330	biolink:NamedThing	palmitoyl-[acp] elongase/decarboxylase activity	Catalysis of the reaction: malonyl-CoA + a palmitoyl-[acp] = 1-heptadecene + 2 carbon dioxide + coenzyme A + a holo-[acyl-carrier protein].	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-13258									molecular_function											owl:Class	
GO:0016747	biolink:NamedThing	acyltransferase activity, transferring groups other than amino-acyl groups	Catalysis of the transfer of an acyl group, other than amino-acyl, from one compound (donor) to another (acceptor).	tmpzr1t_l9r_go_relaxed.owl	transferase activity, transferring groups other than amino-acyl groups|transferase activity, transferring acyl groups other than amino-acyl groups	https://github.com/geneontology/go-ontology/issues/20486			EC:2.3.1.-									molecular_function											owl:Class	
GO:0005335	biolink:NamedThing	serotonin:sodium symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: serotonin(out) + Na+(out) + Cl-(out) = serotonin(in) + Na+(in)+ Cl-(in).	tmpzr1t_l9r_go_relaxed.owl	sodium/serotonin symporter activity|serotonin transmembrane transporter activity|serotonin:sodium:chloride symporter activity				Reactome:R-HSA-444008|RHEA:51196							GO:0015222|GO:0005336		molecular_function											owl:Class	
GO:1901618	biolink:NamedThing	organic hydroxy compound transmembrane transporter activity	Enables the transfer of organic hydroxy compound from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl								pr	2012-11-13T12:59:01Z					molecular_function											owl:Class	
GO:2001235	biolink:NamedThing	positive regulation of apoptotic signaling pathway	Any process that activates or increases the frequency, rate or extent of apoptotic signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of apoptotic signalling pathway							pr	2011-11-24T01:20:58Z					biological_process											owl:Class	
GO:0035184	biolink:NamedThing	histone threonine kinase activity	Catalysis of the transfer of a phosphate group to a threonine residue of a histone. Histones are any of a group of water-soluble proteins found in association with the DNA of eukaroytic  chromosomes.	tmpzr1t_l9r_go_relaxed.owl	histone-threonine kinase activity													molecular_function											owl:Class	
GO:0004674	biolink:NamedThing	protein serine/threonine kinase activity	Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.	tmpzr1t_l9r_go_relaxed.owl	protein serine kinase activity|protein serine-threonine kinase activity|serine protein kinase activity|protein kinase (phosphorylating) activity|serine/threonine protein kinase activity|serine(threonine) protein kinase activity|protein-serine kinase activity|serine-specific protein kinase activity|threonine-specific protein kinase activity|serine kinase activity|protein threonine kinase activity|protein phosphokinase activity	https://github.com/geneontology/go-ontology/issues/20114			Reactome:R-HSA-5357472|Reactome:R-HSA-9612501|Reactome:R-HSA-5692775|Reactome:R-HSA-6795460|Reactome:R-HSA-199910|Reactome:R-HSA-5672978|Reactome:R-HSA-3249371|Reactome:R-HSA-5675198|Reactome:R-HSA-2399966|Reactome:R-HSA-3000310|Reactome:R-HSA-75820|Reactome:R-HSA-6799332|Reactome:R-HSA-6798372|Reactome:R-HSA-2399985|Reactome:R-HSA-5668984|Reactome:R-HSA-156678|Reactome:R-HSA-3857329|Reactome:R-HSA-5218854|Reactome:R-HSA-8868340|Reactome:R-HSA-4332363|Reactome:R-HSA-156673|Reactome:R-HSA-9023132|Reactome:R-HSA-2028591|Reactome:R-HSA-9662823|Reactome:R-HSA-5682983|Reactome:R-HSA-176116|Reactome:R-HSA-419083|Reactome:R-HSA-9009208|Reactome:R-HSA-165766|Reactome:R-HSA-446701|Reactome:R-HSA-5635842|Reactome:R-HSA-446694|Reactome:R-HSA-200143|Reactome:R-HSA-3371567|Reactome:R-HSA-9032751|Reactome:R-HSA-9652165|Reactome:R-HSA-5610718|Reactome:R-HSA-2028679|Reactome:R-HSA-5692779|Reactome:R-HSA-5213464|Reactome:R-HSA-5218826|Reactome:R-HSA-5357477|Reactome:R-HSA-2176475|Reactome:R-HSA-2399999|Reactome:R-HSA-202510|Reactome:R-HSA-109860|Reactome:R-HSA-349444|Reactome:R-HSA-3209160|Reactome:R-HSA-349455|Reactome:R-HSA-162657|Reactome:R-HSA-165777|Reactome:R-HSA-174119|Reactome:R-HSA-4793911|Reactome:R-HSA-6795290|Reactome:R-HSA-111970|Reactome:R-HSA-448955|Reactome:R-HSA-5679205|Reactome:R-HSA-9624526|Reactome:R-HSA-5687094|Reactome:R-HSA-199839|Reactome:R-HSA-195283|Reactome:R-HSA-165758|Reactome:R-HSA-6799097|Reactome:R-HSA-6805276|Reactome:R-HSA-3928616|Reactome:R-HSA-2214351|Reactome:R-HSA-2028675|Reactome:R-HSA-3928577|Reactome:R-HSA-2466068|Reactome:R-HSA-168140|Reactome:R-HSA-399978|Reactome:R-HSA-5675194|Reactome:R-HSA-937022|Reactome:R-HSA-5671763|Reactome:R-HSA-202222|Reactome:R-HSA-9633008|Reactome:R-HSA-198347|Reactome:R-HSA-2399969|Reactome:R-HSA-419644|Reactome:R-HSA-4551570|Reactome:R-HSA-2574840|Reactome:R-HSA-167084|Reactome:R-HSA-3371435|Reactome:R-HSA-2028629|Reactome:R-HSA-5693575|Reactome:R-HSA-5218814|Reactome:R-HSA-349426|Reactome:R-HSA-8878054|Reactome:R-HSA-9007539|Reactome:R-HSA-450827|Reactome:R-HSA-69608|Reactome:R-HSA-9648883|Reactome:R-HSA-2168079|Reactome:R-HSA-164151|Reactome:R-HSA-451347|Reactome:R-HSA-1362270|Reactome:R-HSA-5682598|Reactome:R-HSA-167098|Reactome:R-HSA-165162|Reactome:R-HSA-188350|Reactome:R-HSA-168053|Reactome:R-HSA-5666160|Reactome:R-HSA-5687086|Reactome:R-HSA-5693551|Reactome:R-HSA-5685156|Reactome:R-HSA-201691|Reactome:R-HSA-9648089|Reactome:R-HSA-170055|Reactome:R-HSA-3229152|Reactome:R-HSA-8868573|Reactome:R-HSA-202541|Reactome:R-HSA-5693540|Reactome:R-HSA-3371531|Reactome:R-HSA-165182|Reactome:R-HSA-2730868|Reactome:R-HSA-5665868|Reactome:R-HSA-5632672|Reactome:R-HSA-198613|Reactome:R-HSA-5610732|Reactome:R-HSA-5685242|Reactome:R-HSA-198756|Reactome:R-HSA-3000327|Reactome:R-HSA-170116|Reactome:R-HSA-187688|Reactome:R-HSA-2399988|Reactome:R-HSA-2028661|Reactome:R-HSA-5082387|Reactome:R-HSA-5693549|Reactome:R-HSA-9620004|Reactome:R-HSA-9612980|Reactome:R-HSA-202500|Reactome:R-HSA-165726|Reactome:R-HSA-5687090|Reactome:R-HSA-448948|Reactome:R-HSA-8850945|Reactome:R-HSA-975180|Reactome:R-HSA-75010|Reactome:R-HSA-3239014|Reactome:R-HSA-450499|Reactome:R-HSA-5668545|Reactome:R-HSA-8942836|Reactome:R-HSA-211650|Reactome:R-HSA-75809|Reactome:R-HSA-4608825|Reactome:R-HSA-8868666|Reactome:R-HSA-450474|Reactome:R-HSA-9673346|Reactome:R-HSA-975160|Reactome:R-HSA-912470|Reactome:R-HSA-8863007|Reactome:R-HSA-199299|Reactome:R-HSA-200421|Reactome:R-HSA-2029469|Reactome:R-HSA-2028598|Reactome:R-HSA-1168635|Reactome:R-HSA-1181156|Reactome:R-HSA-9694620|Reactome:R-HSA-69604|Reactome:R-HSA-9681627|Reactome:R-HSA-6795473|Reactome:R-HSA-199929|Reactome:R-HSA-5632670|Reactome:R-HSA-450463|Reactome:R-HSA-5683792|Reactome:R-HSA-5610730|Reactome:R-HSA-5672973|Reactome:R-HSA-400382|Reactome:R-HSA-9648888|Reactome:R-HSA-5228811|Reactome:R-HSA-9008480|Reactome:R-HSA-389756|Reactome:R-HSA-8948757|Reactome:R-HSA-199298|Reactome:R-HSA-1168638|Reactome:R-HSA-174174|Reactome:R-HSA-2470508|Reactome:R-HSA-5672008|Reactome:R-HSA-199935|Reactome:R-HSA-5685230|Reactome:R-HSA-209087|Reactome:R-HSA-6802926|Reactome:R-HSA-6805059|Reactome:R-HSA-2399981|Reactome:R-HSA-451152|Reactome:R-HSA-937059|Reactome:R-HSA-5624492|Reactome:R-HSA-445072|Reactome:R-HSA-139908|Reactome:R-HSA-5357831|Reactome:R-HSA-5686578|Reactome:R-HSA-5682101|Reactome:R-HSA-6801675|Reactome:R-HSA-9012319|Reactome:R-HSA-2399996|Reactome:R-HSA-211583|Reactome:R-HSA-2562526|Reactome:R-HSA-3928625|Reactome:R-HSA-2730896|Reactome:R-HSA-8863014|Reactome:R-HSA-5690250|Reactome:R-HSA-5694441|Reactome:R-HSA-2028284|Reactome:R-HSA-3928640|Reactome:R-HSA-2430535|Reactome:R-HSA-429714|Reactome:R-HSA-399944|Reactome:R-HSA-9656215|Reactome:R-HSA-165718|Reactome:R-HSA-8878050|Reactome:R-HSA-399950|Reactome:R-HSA-2028555|Reactome:R-HSA-8870558|Reactome:R-HSA-8868260|Reactome:R-HSA-2529020|Reactome:R-HSA-399939|Reactome:R-HSA-1454699|Reactome:R-HSA-8868567|Reactome:R-HSA-8863011|Reactome:R-HSA-9619515|Reactome:R-HSA-166119|Reactome:R-HSA-380272|Reactome:R-HSA-5693598|Reactome:R-HSA-5671919|Reactome:R-HSA-8944454|Reactome:R-HSA-3858480|Reactome:R-HSA-2984258|Reactome:R-HSA-162363|Reactome:R-HSA-198640|Reactome:R-HSA-8856813|Reactome:R-HSA-5693609|Reactome:R-HSA-139918|Reactome:R-HSA-6805785|Reactome:R-HSA-198609|Reactome:R-HSA-6802933|Reactome:R-HSA-170076|Reactome:R-HSA-1225894|Reactome:R-HSA-6802919|Reactome:R-HSA-1632857|Reactome:R-HSA-374696|Reactome:R-HSA-5672828|Reactome:R-HSA-428961|Reactome:R-HSA-9634702|Reactome:R-HSA-392752|Reactome:R-HSA-3928620|Reactome:R-HSA-198371|Reactome:R-HSA-5218821|Reactome:R-HSA-8853444|Reactome:R-HSA-1445144|Reactome:R-HSA-5218916|Reactome:R-HSA-2243938|Reactome:R-HSA-109822|Reactome:R-HSA-9612509|Reactome:R-HSA-3857328|Reactome:R-HSA-9610156|Reactome:R-HSA-5683425|Reactome:R-HSA-8868344|Reactome:R-HSA-69685|Reactome:R-HSA-918229|Reactome:R-HSA-163010|Reactome:R-HSA-198746|Reactome:R-HSA-112342|Reactome:R-HSA-6798374|Reactome:R-HSA-176298|Reactome:R-HSA-381091|Reactome:R-HSA-5668932|Reactome:R-HSA-5669250|Reactome:R-HSA-5668947|Reactome:R-HSA-975853|Reactome:R-HSA-199863|Reactome:R-HSA-6805103|Reactome:R-HSA-5082405|Reactome:R-HSA-5683801|Reactome:R-HSA-77071|Reactome:R-HSA-199895|Reactome:R-HSA-1638803|Reactome:R-HSA-2028589|Reactome:R-HSA-5672010|Reactome:R-HSA-156723|Reactome:R-HSA-3228469|Reactome:R-HSA-5674496|Reactome:R-HSA-6800490|Reactome:R-HSA-6804266|Reactome:R-HSA-111919|Reactome:R-HSA-6805640|Reactome:R-HSA-8933446|Reactome:R-HSA-936951|Reactome:R-HSA-4411383|Reactome:R-HSA-3239019|Reactome:R-HSA-9632868|Reactome:R-HSA-8877691|Reactome:R-HSA-1592233|Reactome:R-HSA-4332388|Reactome:R-HSA-109862|Reactome:R-HSA-450325|Reactome:R-HSA-2730876|Reactome:R-HSA-8854908|Reactome:R-HSA-198270|Reactome:R-HSA-3772435|Reactome:R-HSA-381111|Reactome:R-HSA-9626880|Reactome:R-HSA-419087|Reactome:R-HSA-170977|Reactome:R-HSA-6799246|Reactome:R-HSA-2396007|Reactome:R-HSA-6805126|Reactome:R-HSA-2993898|Reactome:R-HSA-1181149|Reactome:R-HSA-5229343|Reactome:R-HSA-4411402|Reactome:R-HSA-9610163|Reactome:R-HSA-8852306|Reactome:R-HSA-198731|Reactome:R-HSA-6805479|Reactome:R-HSA-5684140|Reactome:R-HSA-193705|Reactome:R-HSA-198621|Reactome:R-HSA-2028670|Reactome:R-HSA-5683964|Reactome:R-HSA-8952289|Reactome:R-HSA-5610722|Reactome:R-HSA-170087|Reactome:R-HSA-9683664|Reactome:R-HSA-1168641|Reactome:R-HSA-8940100|Reactome:R-HSA-3222020|Reactome:R-HSA-9013978|Reactome:R-HSA-5607726|Reactome:R-HSA-933525|Reactome:R-HSA-6802911|Reactome:R-HSA-8852317|Reactome:R-HSA-109702|Reactome:R-HSA-6811454|Reactome:R-HSA-2990880|Reactome:R-HSA-166245|Reactome:R-HSA-195275|Reactome:R-HSA-5687183|Reactome:R-HSA-8939963|Reactome:R-HSA-399952|Reactome:R-HSA-377186|Reactome:R-HSA-156699|Reactome:R-HSA-112381|Reactome:R-HSA-9613530|Reactome:R-HSA-8948146|Reactome:R-HSA-166286|Reactome:R-HSA-9633742|Reactome:R-HSA-6804955|Reactome:R-HSA-442739|Reactome:R-HSA-201717|Reactome:R-HSA-165692|Reactome:R-HSA-5682026|Reactome:R-HSA-2400001|Reactome:R-HSA-193647|Reactome:R-HSA-442832|Reactome:R-HSA-6799409|Reactome:R-HSA-9604328|Reactome:R-HSA-9619843|Reactome:R-HSA-2730900|Reactome:R-HSA-156682|Reactome:R-HSA-6804276|Reactome:R-HSA-419197|Reactome:R-HSA-2029454|Reactome:R-HSA-198611|Reactome:R-HSA-5260201|Reactome:R-HSA-9699579|Reactome:R-HSA-2422927|Reactome:R-HSA-934559|Reactome:R-HSA-199917|Reactome:R-HSA-5686704|Reactome:R-HSA-3229102|Reactome:R-HSA-9656214|Reactome:R-HSA-5687121|Reactome:R-HSA-69891|Reactome:R-HSA-5213466|Reactome:R-HSA-195300|Reactome:R-HSA-2399992|Reactome:R-HSA-975861|Reactome:R-HSA-5607742|Reactome:R-HSA-399951|Reactome:R-HSA-9627089|Reactome:R-HSA-975865|Reactome:R-HSA-975170|Reactome:R-HSA-8873929|Reactome:R-HSA-2028673|Reactome:R-HSA-5218906|Reactome:R-HSA-195318|Reactome:R-HSA-2399977|Reactome:R-HSA-6805285|Reactome:R-HSA-429016|Reactome:R-HSA-1458463|Reactome:R-HSA-109823|Reactome:R-HSA-9022314|Reactome:R-HSA-2984226|Reactome:R-HSA-9008822|Reactome:R-HSA-5578777|Reactome:R-HSA-6810233|Reactome:R-HSA-187949|Reactome:R-HSA-5624473|Reactome:R-HSA-8853419|Reactome:R-HSA-2029460|Reactome:R-HSA-2399941|Reactome:R-HSA-9610153|Reactome:R-HSA-5684887|Reactome:R-HSA-170126|Reactome:R-HSA-5607732|Reactome:R-HSA-975125|Reactome:R-HSA-9653503|Reactome:R-HSA-198599|Reactome:R-HSA-1549526|Reactome:R-HSA-9645535|Reactome:R-HSA-3928608|Reactome:R-HSA-975134|Reactome:R-HSA-6788392|Reactome:R-HSA-5693536|Reactome:R-HSA-5684096|Reactome:R-HSA-211164|Reactome:R-HSA-450222|Reactome:R-HSA-2243942|Reactome:R-HSA-5675868|Reactome:R-HSA-3222006|Reactome:R-HSA-1181355|Reactome:R-HSA-9032863|Reactome:R-HSA-4088134|Reactome:R-HSA-202459|Reactome:R-HSA-3132737|Reactome:R-HSA-450490|Reactome:R-HSA-3769394|Reactome:R-HSA-2399982|Reactome:R-HSA-6801666|Reactome:R-HSA-4332358|Reactome:R-HSA-975874|Reactome:R-HSA-2294580|Reactome:R-HSA-2060328|Reactome:R-HSA-202437|Reactome:R-HSA-913996|Reactome:R-HSA-2028583|Reactome:R-HSA-8868118|Reactome:R-HSA-6802973|Reactome:R-HSA-6802943|Reactome:R-HSA-201677|Reactome:R-HSA-8863895|Reactome:R-HSA-195287|Reactome:R-HSA-1358791|Reactome:R-HSA-8948039|Reactome:R-HSA-8876446|Reactome:R-HSA-163416|Reactome:R-HSA-2730856|Reactome:R-HSA-6805399|Reactome:R-HSA-432110|Reactome:R-HSA-6814409|Reactome:R-HSA-975878|Reactome:R-HSA-198669|Reactome:R-HSA-5627775|Reactome:R-HSA-9694293|Reactome:R-HSA-442724|Reactome:R-HSA-2028635|Reactome:R-HSA-5687101|Reactome:R-HSA-1449597|Reactome:R-HSA-163418|Reactome:R-HSA-5607722|Reactome:R-HSA-5692768|Reactome:R-HSA-5672948|Reactome:R-HSA-6802935|Reactome:R-HSA-166284|Reactome:R-HSA-75028|Reactome:R-HSA-5635841							GO:0004695|GO:0004696|GO:0106311|GO:0004700		molecular_function											owl:Class	
GO:0097217	biolink:NamedThing	sieve area	A pit-like area in the cell wall of a sieve element; contains pores lined with callose and occupied by strands of protoplasmic material that interconnect the protoplasts of contiguous sieve elements.	tmpzr1t_l9r_go_relaxed.owl						Part of a sieve element (PO:0025406).		pr	2012-01-13T05:39:03Z					cellular_component											owl:Class	
GO:0010456	biolink:NamedThing	cell proliferation in dorsal spinal cord	The multiplication or reproduction of cells, resulting in the expansion of the dorsal spinal cord cell population.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0061351	biolink:NamedThing	neural precursor cell proliferation	The multiplication or reproduction of neural precursor cells, resulting in the expansion of a cell population. A neural precursor cell is either a nervous system stem cell or a nervous system progenitor cell.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-10-01T11:06:04Z					biological_process											owl:Class	
GO:0001049	biolink:NamedThing	RNA polymerase V core binding	Binding to RNA polymerase V core enzyme, a multisubunit eukaryotic nuclear RNA polymerase found in plants and involved in production of noncoding transcripts at target loci for silencing.	tmpzr1t_l9r_go_relaxed.owl								krc	2010-09-23T01:41:08Z					molecular_function											owl:Class	
GO:0043175	biolink:NamedThing	RNA polymerase core enzyme binding	Binding to an RNA polymerase core enzyme, containing a specific subunit composition defined as the core enzyme.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0034647	biolink:NamedThing	histone H3-tri/di/monomethyl-lysine-4 demethylase activity	Catalysis of the removal of a methyl group from a tri, a di or a monomethyl-lysine residue at position 4 of the histone H3 protein. This is a dioxygenase reaction that is dependent on Fe(II) and 2-oxoglutarate.	tmpzr1t_l9r_go_relaxed.owl	histone H3-K4me2 demethylase activity|histone H3-K4me3 demethylase activity|histone demethylase activity (H3-trimethyl-K4 specific)|H3K4me3 demethylase activity|histone demethylase activity (H3-K4-me3 specific)|histone H3K4me2 demethylase activity	https://github.com/geneontology/go-ontology/issues/21089			EC:1.14.11.67|RHEA:60208									molecular_function											owl:Class	
GO:0032453	biolink:NamedThing	histone H3-methyl-lysine-4 demethylase activity	Catalysis of the removal of a methyl group from a modified lysine residue at position 4 of the histone H3 protein.	tmpzr1t_l9r_go_relaxed.owl	histone demethylase activity (H3-K4 specific)|histone H3K4 demethylase activity	https://github.com/geneontology/go-ontology/issues/21089												molecular_function											owl:Class	
GO:0051283	biolink:NamedThing	negative regulation of sequestering of calcium ion	Any process that stops, prevents, or reduces the frequency, rate or extent of the binding or confining calcium ions such that they are separated from other components of a biological system.	tmpzr1t_l9r_go_relaxed.owl	down regulation of sequestering of calcium ion|negative regulation of calcium ion (Ca2+) sequestering|downregulation of sequestering of calcium ion|negative regulation of calcium ion (Ca2+) retention|negative regulation of sequestering of calcium ion (Ca2+)|negative regulation of retention of calcium ion (Ca2+)|negative regulation of sequestration of calcium ion (Ca2+)|inhibition of sequestering of calcium ion|negative regulation of storage of calcium ion (Ca2+)|negative regulation of calcium ion (Ca2+) sequestration|down-regulation of sequestering of calcium ion|negative regulation of calcium ion (Ca2+) storage													biological_process											owl:Class	
GO:0019384	biolink:NamedThing	caprolactam catabolic process	The chemical reactions and pathways resulting in the breakdown of caprolactam, hexahydro-2h-azepin-2-one, a cyclic amide of caproic acid.	tmpzr1t_l9r_go_relaxed.owl	caprolactam catabolism|caprolactam breakdown|caprolactam degradation				MetaCyc:P621-PWY									biological_process											owl:Class	
GO:1901565	biolink:NamedThing	organonitrogen compound catabolic process	The chemical reactions and pathways resulting in the breakdown of organonitrogen compound.	tmpzr1t_l9r_go_relaxed.owl	organonitrogen compound breakdown|organonitrogen compound degradation|organonitrogen compound catabolism							pr	2012-11-04T15:17:56Z					biological_process											owl:Class	
GO:1902061	biolink:NamedThing	betaine aldehyde metabolic process	The chemical reactions and pathways involving betaine aldehyde.	tmpzr1t_l9r_go_relaxed.owl	betaine aldehyde metabolism							di	2013-04-16T12:07:03Z					biological_process											owl:Class	
GO:0046119	biolink:NamedThing	7-methylguanosine catabolic process	The chemical reactions and pathways resulting in the breakdown of 7-methylguanosine, a modified nucleoside that forms a cap at the 5'-terminus of eukaryotic mRNA.	tmpzr1t_l9r_go_relaxed.owl	7-methylguanosine catabolism|7-methylguanosine breakdown|7-methylguanosine degradation													biological_process											owl:Class	
GO:1901069	biolink:NamedThing	guanosine-containing compound catabolic process	The chemical reactions and pathways resulting in the breakdown of guanosine-containing compounds (guanosines).	tmpzr1t_l9r_go_relaxed.owl	guanosines catabolic process|guanosine-containing compound catabolism|guanosines catabolism|guanosine-containing compound degradation|guanosine-containing compound breakdown|guanosines degradation|guanosines breakdown							bf	2012-07-02T01:52:00Z					biological_process											owl:Class	
GO:0071367	biolink:NamedThing	cellular response to brassinosteroid stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a brassinosteroid stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-12-11T03:13:33Z					biological_process											owl:Class	
GO:0009741	biolink:NamedThing	response to brassinosteroid	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a brassinosteroid stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to brassinosteroid stimulus													biological_process											owl:Class	
GO:1903110	biolink:NamedThing	regulation of single-strand break repair via homologous recombination	Any process that modulates the frequency, rate or extent of single-strand break repair via homologous recombination.	tmpzr1t_l9r_go_relaxed.owl								pr	2014-06-09T12:11:26Z					biological_process											owl:Class	
GO:0043150	biolink:NamedThing	DNA synthesis involved in double-strand break repair via homologous recombination	The synthesis of DNA that contributes to the process of double-strand break repair via homologous recombination.	tmpzr1t_l9r_go_relaxed.owl	DNA synthesis during double-strand break repair via homologous recombination													biological_process											owl:Class	
GO:0071897	biolink:NamedThing	DNA biosynthetic process	The cellular DNA metabolic process resulting in the formation of DNA, deoxyribonucleic acid, one of the two main types of nucleic acid, consisting of a long unbranched macromolecule formed from one or two strands of linked deoxyribonucleotides, the 3'-phosphate group of each constituent deoxyribonucleotide being joined in 3',5'-phosphodiester linkage to the 5'-hydroxyl group of the deoxyribose moiety of the next one.	tmpzr1t_l9r_go_relaxed.owl	DNA anabolism|DNA formation|DNA synthesis|DNA biosynthesis							mah	2010-09-15T02:14:33Z					biological_process											owl:Class	
GO:1902977	biolink:NamedThing	mitotic DNA replication preinitiation complex assembly	Any DNA replication preinitiation complex assembly that is involved in mitotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl	pre-IC complex assembly involved in mitotic cell cycle|DNA replication preinitiation complex formation involved in mitotic cell cycle							jl	2014-05-06T19:19:37Z					biological_process											owl:Class	
GO:0071163	biolink:NamedThing	DNA replication preinitiation complex assembly	The aggregation, arrangement and bonding together of a set of components to form the DNA replication preinitiation complex, a protein-DNA complex that is assembled at DNA replication origins immediately prior to the initiation of DNA replication. The complex consists of proteins that initiate the DNA binding, melt the helix and enable helicase activity.	tmpzr1t_l9r_go_relaxed.owl	DNA replication preinitiation complex formation|pre-IC complex assembly							mah	2009-11-19T11:13:41Z			GO:1902293|GO:1902316		biological_process											owl:Class	
GO:0050050	biolink:NamedThing	leucine N-acetyltransferase activity	Catalysis of the reaction: L-leucine + acetyl-CoA = N-acetyl-L-leucine + CoA + H(+).	tmpzr1t_l9r_go_relaxed.owl	leucine acetyltransferase activity|acetyl-CoA:L-leucine N-acetyltransferase activity				MetaCyc:LEUCINE-N-ACETYLTRANSFERASE-RXN|KEGG_REACTION:R01089|EC:2.3.1.66|RHEA:20089									molecular_function											owl:Class	
GO:0008080	biolink:NamedThing	N-acetyltransferase activity	Catalysis of the transfer of an acetyl group to a nitrogen atom on the acceptor molecule.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-2473152|Reactome:R-HSA-9636560|Reactome:R-HSA-6790987|Reactome:R-HSA-2468039									molecular_function											owl:Class	
GO:0061571	biolink:NamedThing	TDP phosphorylation	The process of introducing a phosphate group into TDP to produce a TTP.	tmpzr1t_l9r_go_relaxed.owl								dph	2013-08-01T13:03:34Z					biological_process											owl:Class	
GO:0006165	biolink:NamedThing	nucleoside diphosphate phosphorylation	The process of introducing a phosphate group into a nucleoside diphosphate to produce a nucleoside triphosphate.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0050848	biolink:NamedThing	regulation of calcium-mediated signaling	Any process that modulates the frequency, rate or extent of calcium-mediated signaling, the process in which a cell uses calcium ions to convert an extracellular signal into a response.	tmpzr1t_l9r_go_relaxed.owl	regulation of calcium-mediated signalling													biological_process											owl:Class	
GO:0070258	biolink:NamedThing	inner membrane pellicle complex	A membrane structure formed of two closely aligned lipid bilayers that lie beneath the plasma membrane and form part of the pellicle surrounding an apicomplexan parasite cell.	tmpzr1t_l9r_go_relaxed.owl	inner membrane complex													cellular_component											owl:Class	
GO:0060897	biolink:NamedThing	neural plate regionalization	The pattern specification process that results in the subdivision of an axis or axes of the neural plate in space to define an area or volume in which specific patterns of cell differentiation will take place or in which cells interpret a specific environment.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-08-13T02:09:04Z					biological_process											owl:Class	
GO:0071553	biolink:NamedThing	G protein-coupled pyrimidinergic nucleotide receptor activity	Combining with a pyrimidine nucleotide and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.	tmpzr1t_l9r_go_relaxed.owl	pyrimidinergic nucleotide receptor activity, G-protein coupled|G-protein coupled pyrimidinergic nucleotide receptor activity|pyrimidinergic nucleotide receptor activity, G protein coupled|G protein coupled pyrimidinergic nucleotide receptor activity							mah	2010-01-13T03:13:22Z					molecular_function											owl:Class	
GO:0016502	biolink:NamedThing	nucleotide receptor activity	Combining with a nucleotide and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. A nucleotide is a compound that consists of a nucleoside esterified with a phosphate molecule.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:2001005	biolink:NamedThing	positive regulation of pectin catabolic process	Any process that activates or increases the frequency, rate or extent of pectin catabolic process.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of pectin degradation|positive regulation of pectin breakdown|positive regulation of pectin catabolism							tt	2011-08-08T03:24:09Z					biological_process											owl:Class	
GO:0009896	biolink:NamedThing	positive regulation of catabolic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of catabolic process|upregulation of catabolic process|up regulation of catabolic process|activation of catabolic process|stimulation of catabolic process|positive regulation of degradation|positive regulation of catabolism|positive regulation of breakdown													biological_process											owl:Class	
GO:0010115	biolink:NamedThing	regulation of abscisic acid biosynthetic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of abscisic acid.	tmpzr1t_l9r_go_relaxed.owl	regulation of abscisic acid anabolism|regulation of abscisic acid biosynthesis|regulation of abscisic acid synthesis|regulation of abscisic acid formation													biological_process											owl:Class	
GO:0006213	biolink:NamedThing	pyrimidine nucleoside metabolic process	The chemical reactions and pathways involving any pyrimidine nucleoside, one of a family of organic molecules consisting of a pyrimidine base covalently bonded to ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside).	tmpzr1t_l9r_go_relaxed.owl	pyrimidine metabolism|pyrimidine metabolic process|pyrimidine nucleoside metabolism													biological_process											owl:Class	
GO:0009116	biolink:NamedThing	nucleoside metabolic process	The chemical reactions and pathways involving a nucleoside, a nucleobase linked to either beta-D-ribofuranose (a ribonucleoside) or 2-deoxy-beta-D-ribofuranose, (a deoxyribonucleoside), e.g. adenosine, guanosine, inosine, cytidine, uridine and deoxyadenosine, deoxyguanosine, deoxycytidine and thymidine (= deoxythymidine).	tmpzr1t_l9r_go_relaxed.owl	nucleoside metabolism													biological_process											owl:Class	
GO:0080052	biolink:NamedThing	response to histidine	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a histidine stimulus.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0043200	biolink:NamedThing	response to amino acid	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amino acid stimulus. An amino acid is a carboxylic acids containing one or more amino groups.	tmpzr1t_l9r_go_relaxed.owl	response to amino acid stimulus											GO:0010237		biological_process											owl:Class	
GO:0044377	biolink:NamedThing	RNA polymerase II cis-regulatory region sequence-specific DNA binding, bending	Binding to a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site) located in cis relative to the transcription start site (i.e., on the same strand of DNA) of a gene transcribed by RNA polymerase II, and distorting the original structure of DNA, typically a straight helix, into a bend, or increasing the bend if the original structure was intrinsically bent due to its sequence.	tmpzr1t_l9r_go_relaxed.owl	RNA polymerase II promoter proximal region sequence-specific DNA binding, bending|RNA polymerase II proximal promoter sequence-specific DNA binding, bending|RNA polymerase II proximal promoter region sequence-specific DNA binding, bending|RNA polymerase II core promoter proximal region sequence-specific DNA binding, bending							jl	2011-12-08T01:38:21Z					molecular_function											owl:Class	
GO:0044374	biolink:NamedThing	sequence-specific DNA binding, bending	The activity of binding selectively and non-covalently to DNA in a sequence-specific manner and distorting the original structure of DNA, typically a straight helix, into a bend, or increasing the bend if the original structure was intrinsically bent due to its sequence.	tmpzr1t_l9r_go_relaxed.owl	DNA bending involving sequence-specific DNA binding							jl	2011-12-01T04:05:59Z					molecular_function											owl:Class	
GO:1900874	biolink:NamedThing	heptadec-1-ene metabolic process	The chemical reactions and pathways involving heptadec-1-ene.	tmpzr1t_l9r_go_relaxed.owl	heptadec-1-ene metabolism							tt	2012-06-13T01:49:51Z					biological_process											owl:Class	
GO:1905697	biolink:NamedThing	negative regulation of polysome binding	Any process that stops, prevents or reduces the frequency, rate or extent of polysome binding.	tmpzr1t_l9r_go_relaxed.owl	down regulation of polyribosome binding|down regulation of polysome binding|inhibition of polyribosome binding|down-regulation of polysome binding|inhibition of polysome binding|negative regulation of polyribosome binding|downregulation of polyribosome binding|down-regulation of polyribosome binding|downregulation of polysome binding							bc	2016-11-14T23:26:29Z					biological_process											owl:Class	
GO:0051100	biolink:NamedThing	negative regulation of binding	Any process that stops or reduces the rate or extent of binding, the selective interaction of a molecule with one or more specific sites on another molecule.	tmpzr1t_l9r_go_relaxed.owl	down regulation of binding|downregulation of binding|down-regulation of binding|inhibition of binding													biological_process											owl:Class	
GO:0005309	biolink:NamedThing	creatine:sodium symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: creatine(out) + Na+(out) = creatine(in) + Na+(in).	tmpzr1t_l9r_go_relaxed.owl	sodium/chloride-dependent creatine transporter				Reactome:R-HSA-200396									molecular_function											owl:Class	
GO:0015370	biolink:NamedThing	solute:sodium symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: solute(out) + Na+(out) = solute(in) + Na+(in).	tmpzr1t_l9r_go_relaxed.owl	proline/glycine/betaine:hydrogen/sodium symporter activity				Reactome:R-HSA-8876283									molecular_function											owl:Class	
GO:0110016	biolink:NamedThing	B-WICH complex	A chromatin remodeling complex that positively regulates histone H3 acetylation, in particular H3K9, by recruiting histone acetyltransferases to rDNA gene regions. Located in the nucleolus where it assembles on RNA Polymerase I (Pol I) and possibly on RNA Polymerase III (Pol III) promoter and coding regions during early G1 phase and activates the post-initiation phases of Pol I transcription. May also activate RNA Polymerase II (Pol II) gene transcription. In mammals, B-WICH contains the WICH complex core of BAZ1B and SMARCA5, additional protein subunits and possibly rRNAs. Although it contains several catalytic subunits it is not clear which functions are carried out by the complex itself.	tmpzr1t_l9r_go_relaxed.owl						An example is BAZ1B (Q9UIG0) in human in PMID:16603771 (by IPI).		kmv	2017-05-26T19:53:53Z					cellular_component											owl:Class	
GO:0070603	biolink:NamedThing	SWI/SNF superfamily-type complex	A protein complex that contains an ortholog of the Saccharomyces ATPase Swi2/Snf2 as one of the catalytic subunit components (ATPase) and mediates assembly of nucleosomes, changes to the spacing or structure of nucleosomes, or some combination of those activities in a manner that requires ATP.	tmpzr1t_l9r_go_relaxed.owl	SWI-SNF-type complex|BAF-type complex|SWI2/SNF2 superfamily ATP-dependent chromatin remodeling complex|SWI-SNF global transcription activator complex|SWI/SNF-type complex							mah	2009-04-29T12:55:46Z			GO:0090544		cellular_component											owl:Class	
GO:0070577	biolink:NamedThing	lysine-acetylated histone binding	Binding to a histone in which a lysine residue has been modified by acetylation.	tmpzr1t_l9r_go_relaxed.owl	acetylated histone residue binding							mah	2009-04-21T03:03:35Z					molecular_function											owl:Class	
GO:0140033	biolink:NamedThing	acetylation-dependent protein binding	Binding to a protein upon acetylation of the target protein.	tmpzr1t_l9r_go_relaxed.owl						This term should only be used when the binding is shown to require acetylation of the target protein: the interaction needs to be tested with and without the PTM. The binding does not need to be at the site of acetylation. It may be that the acetylation causes a conformational change that allows binding of the protein to another region; this type of acetylation-dependent protein binding is valid for annotation to this term.		pg	2017-05-17T15:35:43Z					molecular_function											owl:Class	
GO:0048863	biolink:NamedThing	stem cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a stem cell. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Stem_cell_differentiation									biological_process											owl:Class	
GO:0071893	biolink:NamedThing	BMP signaling pathway involved in nephric duct formation	A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, which contributes to nephric duct formation.	tmpzr1t_l9r_go_relaxed.owl	BMP signalling pathway involved in nephric duct formation							mah	2010-09-14T03:14:59Z					biological_process											owl:Class	
GO:0030509	biolink:NamedThing	BMP signaling pathway	A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.	tmpzr1t_l9r_go_relaxed.owl	dpp receptor signalling pathway|decapentaplegic receptor signaling pathway|BMP receptor signaling pathway|BMP signalling pathway|dpp signaling pathway|decapentaplegic signaling pathway|bone morphogenetic protein signalling pathway|bone morphogenetic protein signaling pathway|dpp receptor signaling pathway|decapentaplegic receptor signalling pathway											GO:0008101		biological_process											owl:Class	
GO:0044494	biolink:NamedThing	envenomation resulting in positive regulation of voltage-gated sodium channel activity in other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant activation or increase in the activity of the activity of a voltage-gated sodium channel in the bitten organism.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-02-01T01:29:25Z					biological_process											owl:Class	
GO:0044492	biolink:NamedThing	envenomation resulting in modulation of voltage-gated sodium channel activity in other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with a resultant change in the activity of a voltage-gated sodium channel in the bitten organism.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-02-01T01:23:04Z					biological_process											owl:Class	
GO:0099034	biolink:NamedThing	anchored component of postsynaptic endosome membrane	The component of the postsynaptic endosome membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0031225	biolink:NamedThing	anchored component of membrane	The component of a membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping.	tmpzr1t_l9r_go_relaxed.owl	anchored to membrane													cellular_component											owl:Class	
GO:2000185	biolink:NamedThing	regulation of phosphate transmembrane transport	Any process that modulates the frequency, rate or extent of phosphate transmembrane transport.	tmpzr1t_l9r_go_relaxed.owl	regulation of phosphate membrane transport							vw	2010-10-15T11:33:04Z					biological_process											owl:Class	
GO:0001662	biolink:NamedThing	behavioral fear response	An acute behavioral change resulting from a perceived external threat.	tmpzr1t_l9r_go_relaxed.owl	behavioural fear response													biological_process											owl:Class	
GO:0042596	biolink:NamedThing	fear response	The response of an organism to a perceived external threat.	tmpzr1t_l9r_go_relaxed.owl	physiological fear response											GO:0001663		biological_process											owl:Class	
GO:1902993	biolink:NamedThing	positive regulation of amyloid precursor protein catabolic process	Any process that activates or increases the frequency, rate or extent of amyloid precursor protein catabolic process.	tmpzr1t_l9r_go_relaxed.owl	up regulation of amyloid precursor protein catabolic process|activation of amyloid precursor protein breakdown|up regulation of APP catabolic process|up-regulation of amyloid precursor protein degradation|positive regulation of APP catabolism|activation of amyloid precursor protein degradation|upregulation of APP catabolism|upregulation of APP catabolic process|upregulation of amyloid precursor protein catabolic process|up-regulation of APP catabolism|positive regulation of APP catabolic process|up regulation of amyloid precursor protein catabolism|up-regulation of amyloid precursor protein catabolic process|up regulation of APP catabolism|up-regulation of amyloid precursor protein catabolism|upregulation of amyloid precursor protein breakdown|positive regulation of amyloid precursor protein catabolism|activation of APP catabolism|activation of APP catabolic process|positive regulation of amyloid precursor protein breakdown|up-regulation of APP catabolic process|positive regulation of amyloid precursor protein degradation|up-regulation of amyloid precursor protein breakdown|up regulation of amyloid precursor protein breakdown|activation of amyloid precursor protein catabolism|upregulation of amyloid precursor protein degradation|up regulation of amyloid precursor protein degradation|activation of amyloid precursor protein catabolic process|upregulation of amyloid precursor protein catabolism							rl	2014-05-08T14:21:16Z					biological_process											owl:Class	
GO:0009193	biolink:NamedThing	pyrimidine ribonucleoside diphosphate metabolic process	The chemical reactions and pathways involving pyrimidine ribonucleoside diphosphate, a compound consisting of a pyrimidine base linked to a ribose sugar esterified with diphosphate on the sugar.	tmpzr1t_l9r_go_relaxed.owl	pyrimidine ribonucleoside diphosphate metabolism													biological_process											owl:Class	
GO:0099012	biolink:NamedThing	neuronal dense core vesicle membrane	The lipid bilayer surrounding a neuronal dense core vesicle.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0032127	biolink:NamedThing	dense core granule membrane	The lipid bilayer surrounding a dense core granule.	tmpzr1t_l9r_go_relaxed.owl	dense core vesicle membrane													cellular_component											owl:Class	
GO:0032229	biolink:NamedThing	negative regulation of synaptic transmission, GABAergic	Any process that stops, prevents, or reduces the frequency, rate or extent of GABAergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter gamma-aminobutyric acid (GABA).	tmpzr1t_l9r_go_relaxed.owl	down-regulation of synaptic transmission, GABAergic|inhibition of synaptic transmission, GABAergic|down regulation of synaptic transmission, GABAergic|downregulation of synaptic transmission, GABAergic													biological_process											owl:Class	
GO:0050805	biolink:NamedThing	negative regulation of synaptic transmission	Any process that stops, prevents, or reduces the frequency, rate or extent of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse.	tmpzr1t_l9r_go_relaxed.owl	inhibition of synaptic transmission|down-regulation of synaptic transmission|downregulation of synaptic transmission|down regulation of synaptic transmission													biological_process											owl:Class	
GO:0051048	biolink:NamedThing	negative regulation of secretion	Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of a substance from a cell or a tissue.	tmpzr1t_l9r_go_relaxed.owl	downregulation of secretion|inhibition of secretion|down-regulation of secretion|down regulation of secretion													biological_process											owl:Class	
GO:1905127	biolink:NamedThing	negative regulation of axo-dendritic protein transport	Any process that stops, prevents or reduces the frequency, rate or extent of axo-dendritic protein transport.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of axonal protein transport|down regulation of axonal protein transport|inhibition of axonal protein transport|downregulation of axonal protein transport|down regulation of axo-dendritic protein transport|downregulation of axo-dendritic protein transport|inhibition of axo-dendritic protein transport|down-regulation of axo-dendritic protein transport|negative regulation of axonal protein transport							sl	2016-04-11T20:38:40Z					biological_process											owl:Class	
GO:1905126	biolink:NamedThing	regulation of axo-dendritic protein transport	Any process that modulates the frequency, rate or extent of axo-dendritic protein transport.	tmpzr1t_l9r_go_relaxed.owl	regulation of axonal protein transport							sl	2016-04-11T20:38:31Z					biological_process											owl:Class	
GO:0032013	biolink:NamedThing	negative regulation of ARF protein signal transduction	Any process that stops, prevents, or reduces the frequency, rate or extent of ARF protein signal transduction.	tmpzr1t_l9r_go_relaxed.owl	inhibition of ARF protein signal transduction|downregulation of ARF protein signal transduction|down-regulation of ARF protein signal transduction|down regulation of ARF protein signal transduction													biological_process											owl:Class	
GO:0046580	biolink:NamedThing	negative regulation of Ras protein signal transduction	Any process that stops, prevents, or reduces the frequency, rate or extent of Ras protein signal transduction.	tmpzr1t_l9r_go_relaxed.owl	down regulation of Ras protein signal transduction|down-regulation of Ras protein signal transduction|inhibition of Ras protein signal transduction|downregulation of Ras protein signal transduction													biological_process											owl:Class	
GO:1901568	biolink:NamedThing	fatty acid derivative metabolic process	The chemical reactions and pathways involving fatty acid derivative.	tmpzr1t_l9r_go_relaxed.owl	fatty acid derivative metabolism							pr	2012-11-04T17:13:36Z					biological_process											owl:Class	
GO:0048070	biolink:NamedThing	regulation of developmental pigmentation	Any process that modulates the frequency, rate or extent of the developmental process that results in the deposition of coloring matter in an organism.	tmpzr1t_l9r_go_relaxed.owl	regulation of pigmentation during development													biological_process											owl:Class	
GO:1903333	biolink:NamedThing	negative regulation of protein folding	Any process that stops, prevents or reduces the frequency, rate or extent of protein folding.	tmpzr1t_l9r_go_relaxed.owl	inhibition of protein folding|downregulation of protein complex assembly, multichaperone pathway|negative regulation of co-chaperone activity|inhibition of co-chaperone activity|inhibition of co-chaperonin activity|downregulation of protein folding|down-regulation of co-chaperonin activity|down regulation of alpha-tubulin folding|down-regulation of non-chaperonin molecular chaperone ATPase activity|negative regulation of chaperonin ATPase activity|negative regulation of chaperone activity|down-regulation of alpha-tubulin folding|down regulation of chaperonin-mediated tubulin folding|inhibition of beta-tubulin folding|down-regulation of co-chaperone activity|down regulation of co-chaperonin activity|down regulation of protein complex assembly, multichaperone pathway|down regulation of beta-tubulin folding|negative regulation of protein complex assembly, multichaperone pathway|inhibition of non-chaperonin molecular chaperone ATPase activity|down regulation of co-chaperone activity|down-regulation of protein folding|negative regulation of alpha-tubulin folding|downregulation of alpha-tubulin folding|down regulation of chaperone activity|down regulation of protein folding|inhibition of chaperone activity|downregulation of chaperonin ATPase activity|downregulation of co-chaperone activity|downregulation of non-chaperonin molecular chaperone ATPase activity|inhibition of protein complex assembly, multichaperone pathway|negative regulation of non-chaperonin molecular chaperone ATPase activity|inhibition of chaperonin ATPase activity|downregulation of chaperone activity|negative regulation of chaperonin-mediated tubulin folding|downregulation of chaperonin-mediated tubulin folding|inhibition of chaperonin-mediated tubulin folding|down regulation of non-chaperonin molecular chaperone ATPase activity|down-regulation of beta-tubulin folding|down-regulation of protein complex assembly, multichaperone pathway|inhibition of alpha-tubulin folding|downregulation of glycoprotein-specific chaperone activity|negative regulation of glycoprotein-specific chaperone activity|down-regulation of chaperonin ATPase activity|inhibition of glycoprotein-specific chaperone activity|down-regulation of glycoprotein-specific chaperone activity|negative regulation of beta-tubulin folding|down-regulation of chaperone activity|down-regulation of chaperonin-mediated tubulin folding|down regulation of glycoprotein-specific chaperone activity|downregulation of beta-tubulin folding|negative regulation of co-chaperonin activity|down regulation of chaperonin ATPase activity|downregulation of co-chaperonin activity							vw	2014-08-18T13:14:42Z					biological_process											owl:Class	
GO:0015782	biolink:NamedThing	CMP-N-acetylneuraminate transmembrane transport	The directed movement of CMP-N-acetylneuraminate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	CMP-N-acetylneuraminate transport|CMP-sialic acid transport													biological_process											owl:Class	
GO:0097183	biolink:NamedThing	protein C inhibitor-coagulation factor XI complex	A heterodimeric protein complex that contains protein C inhibitor (SERPINA5) and coagulation factor XI (F11); formation of the complex inhibits the serine protease activity of coagulation factor XI.	tmpzr1t_l9r_go_relaxed.owl	protein C inhibitor-F11 complex|PCI-coagulation factor XI complex|SERPINA5-coagulation factor XI complex|serpin A5-coagulation factor XI complex|plasma serine protease inhibitor-coagulation factor XI complex							pr	2011-10-16T09:03:22Z					cellular_component											owl:Class	
GO:0097180	biolink:NamedThing	serine protease inhibitor complex	A heterodimeric protein complex that contains a serine protease inhibitor and a protease; formation of the complex inhibits serine protease activity.	tmpzr1t_l9r_go_relaxed.owl	serine-type endopeptidase inhibitor complex|serpin complex							pr	2011-10-16T08:55:17Z					cellular_component											owl:Class	
GO:1990798	biolink:NamedThing	pancreas regeneration	The regrowth of a destroyed pancreas.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-07-10T22:53:53Z					biological_process											owl:Class	
GO:0031100	biolink:NamedThing	animal organ regeneration	The regrowth of a lost or destroyed animal organ.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0007278	biolink:NamedThing	pole cell fate determination	The cell fate determination process in which a cell becomes capable of differentiating autonomously into a pole cell regardless of its environment; upon determination, the cell fate cannot be reversed.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1904565	biolink:NamedThing	response to 1-oleoyl-sn-glycerol 3-phosphate	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 1-oleoyl-sn-glycerol 3-phosphate stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to oleoyl lysophosphatidic acid|response to lysophosphatidic acid|response to LPA|response to 1-oleoyl lysophosphatidic acid|response to oleoyl-L-alpha-lysophosphatidic acid							sl	2015-08-19T15:36:48Z					biological_process											owl:Class	
GO:0046683	biolink:NamedThing	response to organophosphorus	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organophosphorus stimulus. Organophosphorus is a compound containing phosphorus bound to an organic molecule; several organophosphorus compounds are used as insecticides, and they are highly toxic cholinesterase inhibitors.	tmpzr1t_l9r_go_relaxed.owl	organophosphorus susceptibility/resistance|organophosphorus resistance													biological_process											owl:Class	
GO:1900930	biolink:NamedThing	negative regulation of L-tyrosine import across plasma membrane	Any process that stops, prevents or reduces the frequency, rate or extent of L-tyrosine import into the cell.	tmpzr1t_l9r_go_relaxed.owl	inhibition of L-tyrosine import|inhibition of L-tyrosine uptake|downregulation of L-tyrosine import|downregulation of L-tyrosine uptake|down regulation of L-tyrosine import|down regulation of L-tyrosine uptake|down-regulation of L-tyrosine import|negative regulation of L-tyrosine uptake|negative regulation of L-tyrosine import|down-regulation of L-tyrosine uptake							al	2012-06-13T07:43:14Z					biological_process											owl:Class	
GO:1900929	biolink:NamedThing	regulation of L-tyrosine import across plasma membrane	Any process that modulates the frequency, rate or extent of L-tyrosine import into the cell.	tmpzr1t_l9r_go_relaxed.owl	regulation of L-tyrosine uptake|regulation of L-tyrosine import							al	2012-06-13T07:42:52Z					biological_process											owl:Class	
GO:2001309	biolink:NamedThing	gliotoxin catabolic process	The chemical reactions and pathways resulting in the breakdown of the epipolythiodioxopiperazine gliotoxin, a poisonous substance produced by some species of fungi.	tmpzr1t_l9r_go_relaxed.owl	gliotoxin breakdown|gliotoxin catabolism|gliotoxin degradation							pr	2012-03-15T03:42:14Z					biological_process											owl:Class	
GO:0008999	biolink:NamedThing	ribosomal-protein-alanine N-acetyltransferase activity	Catalysis of the reaction: acetyl-CoA + ribosomal-protein L-alanine = CoA + ribosomal-protein N-acetyl-L-alanine.	tmpzr1t_l9r_go_relaxed.owl	acetyl-CoA:ribosomal-protein-L-alanine N-acetyltransferase activity|ribosomal protein S18 acetyltransferase activity				EC:2.3.1.267|MetaCyc:2.3.1.128-RXN									molecular_function											owl:Class	
GO:0004596	biolink:NamedThing	peptide alpha-N-acetyltransferase activity	Catalysis of the reaction: acetyl-CoA + peptide = CoA + N-alpha-acetylpeptide. This reaction is the acetylation of the N-terminal amino acid residue of a peptide or protein.	tmpzr1t_l9r_go_relaxed.owl	acetyl-CoA:peptide alpha-N-acetyltransferase activity|amino-terminal amino acid-acetylating enzyme activity|NAT activity|acetyl-CoA:peptide nalpha-acetyltransferase activity|protein N-terminal acetyltransferase activity|N(alpha)-acetyltransferase activity|beta-endorphin acetyltransferase activity|nalpha-acetyltransferase activity|peptide acetyltransferase activity				MetaCyc:PEPTIDE-ALPHA-N-ACETYLTRANSFERASE-RXN|Reactome:R-HSA-6814090									molecular_function											owl:Class	
GO:0070489	biolink:NamedThing	T cell aggregation	The adhesion of one T cell to one or more other T cells via adhesion molecules.	tmpzr1t_l9r_go_relaxed.owl	T-cell aggregation|T lymphocyte aggregation|T-lymphocyte aggregation													biological_process											owl:Class	
GO:0071593	biolink:NamedThing	lymphocyte aggregation	The adhesion of one lymphocyte to one or more other lymphocytes via adhesion molecules.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-01-29T01:37:30Z					biological_process											owl:Class	
GO:0072300	biolink:NamedThing	positive regulation of metanephric glomerulus development	Any process that increases the rate, frequency or extent of metanephric glomerulus development, the progression of the metanephric glomerulus over time from its initial formation until its mature state. The metanephric glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney, or metanephros.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-04-09T05:03:41Z					biological_process											owl:Class	
GO:0008137	biolink:NamedThing	NADH dehydrogenase (ubiquinone) activity	Catalysis of the reaction: NADH + ubiquinone + 5 H(+)(in) <=> NAD(+) + ubiquinol + 4 H(+)(out).	tmpzr1t_l9r_go_relaxed.owl	NADH coenzyme Q1 reductase activity|electron transfer complex I activity|NADH-Q6 oxidoreductase activity|NADH-coenzyme Q reductase activity|ubiquinone reductase activity|DPNH-coenzyme Q reductase activity|NADH-CoQ oxidoreductase activity|NADH-ubiquinone oxidoreductase activity|NADH-ubiquinone reductase activity|mitochondrial electron transport complex I activity|complex I (electron transport chain) activity|NADH-coenzyme Q oxidoreductase activity|NADH-CoQ reductase activity|NADH:ubiquinone oxidoreductase activity|reduced nicotinamide adenine dinucleotide-coenzyme Q reductase activity|NADH-ubiquinone-1 reductase activity|coenzyme Q reductase activity|dihydronicotinamide adenine dinucleotide-coenzyme Q reductase activity|NADH:ubiquinone oxidoreductase complex activity|complex 1 dehydrogenase activity|DPNH-ubiquinone reductase activity|complex I (NADH:Q1 oxidoreductase) activity|mitochondrial electron transport complex 1 activity|type 1 dehydrogenase activity|complex I (mitochondrial electron transport) activity	https://github.com/geneontology/go-ontology/issues/20616|https://github.com/geneontology/go-ontology/issues/21275			Reactome:R-HSA-163217|MetaCyc:NADH-DEHYDROG-A-RXN|MetaCyc:RXN0-5330|EC:7.1.1.2|RHEA:29091									molecular_function											owl:Class	
GO:0050136	biolink:NamedThing	NADH dehydrogenase (quinone) activity	Catalysis of the reaction: NADH + H+ + a quinone = NAD+ + a quinol.	tmpzr1t_l9r_go_relaxed.owl	NADH-quinone oxidoreductase activity|reduced nicotinamide adenine dinucleotide (quinone) dehydrogenase activity|DPNH-menadione reductase activity|D-diaphorase activity|NADH:(quinone-acceptor) oxidoreductase activity				RHEA:46160|MetaCyc:NADH-DEHYDROGENASE-QUINONE-RXN|EC:1.6.5.11									molecular_function											owl:Class	
GO:0046726	biolink:NamedThing	positive regulation by virus of viral protein levels in host cell	Any process where the infecting virus increases the levels of viral proteins in a cell.	tmpzr1t_l9r_go_relaxed.owl	up regulation of viral protein levels in host cell|upregulation of viral protein levels in host cell|positive regulation of viral protein levels|up-regulation of viral protein levels in host cell|activation of viral protein levels in host cell|stimulation of viral protein levels in host cell													biological_process											owl:Class	
GO:0046719	biolink:NamedThing	regulation by virus of viral protein levels in host cell	Any virus-mediated process that modulates the levels of viral proteins in a cell.	tmpzr1t_l9r_go_relaxed.owl	regulation of viral protein levels													biological_process											owl:Class	
GO:1990131	biolink:NamedThing	Gtr1-Gtr2 GTPase complex	A heterodimer GTPase complex. In S. cerevisiae, this complex contains Gtr1p and Gtr2p proteins.	tmpzr1t_l9r_go_relaxed.owl								rb	2013-06-25T20:39:16Z					cellular_component											owl:Class	
GO:0044271	biolink:NamedThing	cellular nitrogen compound biosynthetic process	The chemical reactions and pathways resulting in the formation of organic and inorganic nitrogenous compounds.	tmpzr1t_l9r_go_relaxed.owl	nitrogen compound synthesis|nitrogen compound biosynthesis|nitrogen compound anabolism|nitrogen compound formation													biological_process											owl:Class	
GO:0034641	biolink:NamedThing	cellular nitrogen compound metabolic process	The chemical reactions and pathways involving various organic and inorganic nitrogenous compounds, as carried out by individual cells.	tmpzr1t_l9r_go_relaxed.owl	cellular nitrogen compound metabolism													biological_process											owl:Class	
GO:0043937	biolink:NamedThing	regulation of sporulation	Any process that modulates the frequency, rate or extent of sporulation, the process whose specific outcome is the progression of a spore over time, from its initiation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0050793	biolink:NamedThing	regulation of developmental process	Any process that modulates the frequency, rate or extent of development, the biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0018554	biolink:NamedThing	1,2-dihydroxynaphthalene dioxygenase activity	Catalysis of the reaction: 1,2-dihydroxynaphthalene + O2 = 2-hydroxychromene-2-carboxylate. C6 of the substrate molecular may have an NH2 group attached.	tmpzr1t_l9r_go_relaxed.owl					EC:1.13.11.56|RHEA:27310|UM-BBD_enzymeID:e0255									molecular_function											owl:Class	
GO:0051213	biolink:NamedThing	dioxygenase activity	Catalysis of an oxidation-reduction (redox) reaction in which both atoms of oxygen from one molecule of O2 are incorporated into the (reduced) product(s) of the reaction. The two atoms of oxygen may be distributed between two different products.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-112121|Reactome:R-HSA-112125|Reactome:R-HSA-112120|Reactome:R-HSA-112124									molecular_function											owl:Class	
GO:1901466	biolink:NamedThing	regulation of ferulate catabolic process	Any process that modulates the frequency, rate or extent of ferulate catabolic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of ferulate breakdown|regulation of ferulate catabolism|regulation of ferulate degradation							tt	2012-10-02T14:37:29Z					biological_process											owl:Class	
GO:0010565	biolink:NamedThing	regulation of cellular ketone metabolic process	Any process that modulates the chemical reactions and pathways involving any of a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0004355	biolink:NamedThing	glutamate synthase (NADPH) activity	Catalysis of the reaction: 2 L-glutamate + NADP(+) = 2-oxoglutarate + L-glutamine + H(+) + NADPH. This is a two-step reaction: (a) L-glutamate + NH3 = L-glutamine + H2O, (b) L-glutamate + NADP+ + H2O = NH3 + 2-oxoglutarate + NADPH + H+.	tmpzr1t_l9r_go_relaxed.owl	glutamate (reduced nicotinamide adenine dinucleotide phosphate) synthase activity|GOGAT activity|glutamine-ketoglutaric aminotransferase activity|NADPH-linked glutamate synthase|L-glutamate:NADP+ oxidoreductase (transaminating)|L-glutamate synthase activity|NADPH-dependent glutamate synthase activity|NADPH GOGAT|L-glutamate synthetase activity|glutamine amide-2-oxoglutarate aminotransferase (oxidoreductase, NADP) activity|L-glutamine:2-oxoglutarate aminotransferase, NADPH oxidizing activity|glutamate synthetase (NADP) activity|NADPH-glutamate synthase activity				MetaCyc:GLUGLNSYN-PWY|KEGG_REACTION:R00114|MetaCyc:GLUTSYN-PWY|EC:1.4.1.13|RHEA:15501|MetaCyc:GLUTAMATESYN-RXN	Note that this term has a MetaCyc pathway reference as the pathway only has a single step.								molecular_function											owl:Class	
GO:0045181	biolink:NamedThing	glutamate synthase activity, NAD(P)H as acceptor	Catalysis of the reaction: 2 L-glutamate + NAD(P)+ = L-glutamine + 2-oxoglutarate + NAD(P)H + H+.	tmpzr1t_l9r_go_relaxed.owl	glutamate synthase activity, NADH or NADPH as acceptor													molecular_function											owl:Class	
GO:0016874	biolink:NamedThing	ligase activity	Catalysis of the joining of two molecules, or two groups within a single molecule, using the energy from the hydrolysis of ATP, a similar triphosphate, or a pH gradient.	tmpzr1t_l9r_go_relaxed.owl	synthetase activity	https://github.com/geneontology/go-ontology/issues/19380			EC:6.-.-.-									molecular_function											owl:Class	
GO:0006587	biolink:NamedThing	serotonin biosynthetic process from tryptophan	The chemical reactions and pathways resulting in the formation from tryptophan of serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties.	tmpzr1t_l9r_go_relaxed.owl	serotonin anabolism from tryptophan|serotonin formation from tryptophan|serotonin synthesis from tryptophan													biological_process											owl:Class	
GO:0006568	biolink:NamedThing	tryptophan metabolic process	The chemical reactions and pathways involving tryptophan, the chiral amino acid 2-amino-3-(1H-indol-3-yl)propanoic acid.	tmpzr1t_l9r_go_relaxed.owl	tryptophan metabolism				Wikipedia:Tryptophan									biological_process											owl:Class	
GO:0006742	biolink:NamedThing	NADP catabolic process	The chemical reactions and pathways resulting in the breakdown of nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions; catabolism may be of either the oxidized form, NADP, or the reduced form, NADPH.	tmpzr1t_l9r_go_relaxed.owl	NADP (oxidized) catabolic process|NADP degradation|nicotinamide adenine dinucleotide phosphate catabolism|reduced nicotinamide adenine dinucleotide phosphate catabolism|oxidized NADP catabolism|nicotinamide adenine dinucleotide phosphate catabolic process|reduced NADP catabolic process|NADP (oxidized) catabolism|reduced NADP catabolism|oxidized nicotinamide adenine dinucleotide phosphate catabolic process|NADP breakdown|oxidized nicotinamide adenine dinucleotide phosphate catabolism|NADP (reduced) catabolism|NADPH catabolic process|NADP (reduced) catabolic process|NADP catabolism|reduced nicotinamide adenine dinucleotide phosphate catabolic process|NADPH catabolism|oxidized NADP catabolic process													biological_process											owl:Class	
GO:0019364	biolink:NamedThing	pyridine nucleotide catabolic process	The chemical reactions and pathways resulting in the breakdown of a pyridine nucleotide, a nucleotide characterized by a pyridine derivative as a nitrogen base.	tmpzr1t_l9r_go_relaxed.owl	pyridine nucleotide breakdown|pyridine nucleotide catabolism|pyridine nucleotide degradation													biological_process											owl:Class	
GO:0005813	biolink:NamedThing	centrosome	A structure comprised of a core structure (in most organisms, a pair of centrioles) and peripheral material from which a microtubule-based structure, such as a spindle apparatus, is organized. Centrosomes occur close to the nucleus during interphase in many eukaryotic cells, though in animal cells it changes continually during the cell-division cycle.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Centrosome									cellular_component											owl:Class	
GO:0005815	biolink:NamedThing	microtubule organizing center	An intracellular structure that can catalyze gamma-tubulin-dependent microtubule nucleation and that can anchor microtubules by interacting with their minus ends, plus ends or sides.	tmpzr1t_l9r_go_relaxed.owl	microtubule organising centre|MTOC				Wikipedia:Microtubule_organizing_center									cellular_component											owl:Class	
GO:0036460	biolink:NamedThing	cellular response to cell envelope stress	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stress acting at the cell envelope.	tmpzr1t_l9r_go_relaxed.owl	envelope stress response							bf	2014-01-08T15:15:50Z					biological_process											owl:Class	
GO:0033554	biolink:NamedThing	cellular response to stress	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).	tmpzr1t_l9r_go_relaxed.owl						Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.								biological_process											owl:Class	
GO:2000272	biolink:NamedThing	negative regulation of signaling receptor activity	Any process that stops, prevents or reduces the frequency, rate or extent of a signaling receptor activity.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of signalling receptor activity|negative regulation of receptor activity							bf	2010-12-02T09:28:47Z					biological_process											owl:Class	
GO:0010469	biolink:NamedThing	regulation of signaling receptor activity	Any process that modulates the frequency, rate or extent of a signaling receptor activity. Receptor activity is when a molecule combines with an extracellular or intracellular messenger to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	regulation of receptor activity|regulation of signalling receptor activity													biological_process											owl:Class	
GO:1904642	biolink:NamedThing	cellular response to dinitrophenol	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dinitrophenol stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to dinitrophenols							sl	2015-08-31T20:13:18Z					biological_process											owl:Class	
GO:1904641	biolink:NamedThing	response to dinitrophenol	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dinitrophenol stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to dinitrophenols							sl	2015-08-31T20:13:12Z					biological_process											owl:Class	
GO:0005543	biolink:NamedThing	phospholipid binding	Binding to a phospholipid, a class of lipids containing phosphoric acid as a mono- or diester.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1900740	biolink:NamedThing	positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway	Any process that activates or increases the frequency, rate or extent of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of insertion of proteins into mitochondrial membranes during the induction of apoptosis|activation of protein insertion into mitochondrial membrane during induction of apoptosis|up regulation of protein insertion into mitochondrial membrane involved in induction of apoptosis|upregulation of insertion of proteins into mitochondrial membranes during the induction of apoptosis|up regulation of protein insertion into mitochondrial membrane during induction of apoptosis|upregulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway|up-regulation of protein insertion into mitochondrial membrane during induction of apoptosis|up-regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway|up regulation of insertion of proteins into mitochondrial membranes during the induction of apoptosis|activation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway|up regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway|positive regulation of protein insertion into mitochondrial membrane involved in induction of apoptosis|activation of protein insertion into mitochondrial membrane involved in induction of apoptosis|upregulation of protein insertion into mitochondrial membrane involved in induction of apoptosis|activation of protein insertion into mitochondrion membrane during induction of apoptosis|upregulation of protein insertion into mitochondrial membrane during induction of apoptosis|up regulation of protein insertion into mitochondrion membrane during induction of apoptosis|up-regulation of protein insertion into mitochondrial membrane involved in induction of apoptosis|activation of insertion of proteins into mitochondrial membranes during the induction of apoptosis|up-regulation of protein insertion into mitochondrion membrane during induction of apoptosis|positive regulation of protein insertion into mitochondrial membrane during induction of apoptosis|positive regulation of protein insertion into mitochondrion membrane during induction of apoptosis|up-regulation of insertion of proteins into mitochondrial membranes during the induction of apoptosis|upregulation of protein insertion into mitochondrion membrane during induction of apoptosis							pr	2012-05-28T02:28:40Z					biological_process											owl:Class	
GO:1905477	biolink:NamedThing	positive regulation of protein localization to membrane	Any process that activates or increases the frequency, rate or extent of protein localization to membrane.	tmpzr1t_l9r_go_relaxed.owl	up regulation of protein localization to membrane|up regulation of protein localization in membrane|up-regulation of protein localization to membrane|upregulation of protein localization to membrane|upregulation of protein localization in membrane|up-regulation of protein localisation in membrane|upregulation of protein localisation in membrane|activation of protein localisation in membrane|up regulation of protein localisation in membrane|up-regulation of protein localization in membrane|positive regulation of protein localisation in membrane|activation of protein localization to membrane|positive regulation of protein localization in membrane|activation of protein localization in membrane							bc	2016-09-21T16:20:18Z					biological_process											owl:Class	
GO:0097062	biolink:NamedThing	dendritic spine maintenance	The organization process that preserves a dendritic spine in a stable functional or structural state. A dendritic spine is a specialized protrusion from a neuronal dendrite and is involved in synaptic transmission.	tmpzr1t_l9r_go_relaxed.owl								pr	2011-06-07T11:29:03Z					biological_process											owl:Class	
GO:0097061	biolink:NamedThing	dendritic spine organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a dendritic spine. A dendritic spine is a specialized protrusion from a neuronal dendrite and is involved in synaptic transmission.	tmpzr1t_l9r_go_relaxed.owl	dendritic spine organisation							pr	2011-06-07T11:26:53Z					biological_process											owl:Class	
GO:0043922	biolink:NamedThing	negative regulation by host of viral transcription	Any process in which a host organism stops, prevents, or reduces the frequency, rate or extent of viral transcription.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of viral transcription by host													biological_process											owl:Class	
GO:0051851	biolink:NamedThing	modulation by host of symbiont process	The process in which an organism effects a change in the structure or processes of a symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	modification by host of symbiont morphology or physiology													biological_process											owl:Class	
GO:0016117	biolink:NamedThing	carotenoid biosynthetic process	The chemical reactions and pathways resulting in the formation of carotenoids, tetraterpenoid compounds in which two units of 4 isoprenoid residues joined head-to-tail are themselves joined tail-to-tail.	tmpzr1t_l9r_go_relaxed.owl	carotenoid formation|carotenoid anabolism|carotenoid biosynthesis|carotenoid synthesis				MetaCyc:CAROTENOID-PWY									biological_process											owl:Class	
GO:0016109	biolink:NamedThing	tetraterpenoid biosynthetic process	The chemical reactions and pathways resulting in the formation of tetraterpenoid compounds, terpenoids with eight isoprene units.	tmpzr1t_l9r_go_relaxed.owl	tetraterpenoid biosynthesis|tetraterpene biosynthetic process|tetraterpene biosynthesis|tetraterpenoid anabolism|tetraterpenoid synthesis|tetraterpenoid formation													biological_process											owl:Class	
GO:0090214	biolink:NamedThing	spongiotrophoblast layer developmental growth	The increase in size or mass of the spongiotrophoblast layer of the placenta where the increase in size or mass contributes to the progression of that layer over time from its formation to its mature state.	tmpzr1t_l9r_go_relaxed.owl								tb	2010-01-08T12:10:44Z					biological_process											owl:Class	
GO:0075262	biolink:NamedThing	negative regulation of spore-bearing organ development	Any process that stops, prevents, or reduces the frequency, rate or extent of spore-bearing organ development, a process in which hyphae grow into special aggregates called fruiting bodies that produce new spores.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0051091	biolink:NamedThing	positive regulation of DNA-binding transcription factor activity	Any process that activates or increases the frequency, rate or extent of activity of a transcription factor, any factor involved in the initiation or regulation of transcription.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of thyroid hormone receptor activity|upregulation of transcription factor activity|activation of transcription factor activity|positive regulation of sequence-specific DNA binding transcription factor activity|positive regulation of transcription factor activity|positive regulation of DNA binding transcription factor activity|up regulation of transcription factor activity|stimulation of transcription factor activity|up-regulation of transcription factor activity							rph	2015-04-22T12:22:16Z			GO:1904169		biological_process											owl:Class	
GO:0015360	biolink:NamedThing	acetate:proton symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: acetate(out) + H+(out) = acetate(in) + H+(in).	tmpzr1t_l9r_go_relaxed.owl	acetate:hydrogen symporter activity|hydrogen:acetate symporter activity											GO:0015357		molecular_function											owl:Class	
GO:0043893	biolink:NamedThing	acetate:cation symporter activity	Enables the transfer of acetate from one side of a membrane to the other according to the reaction: acetate(out) + cation(out) = acetate(in) + cation(in).	tmpzr1t_l9r_go_relaxed.owl	cation:acetate symporter activity|cation/acetate symporter activity|acetate/cation symporter activity|ActP|acetate permease|cation-acetate symporter activity|acetate-cation symporter activity													molecular_function											owl:Class	
GO:0051740	biolink:NamedThing	ethylene binding	Binding to ethylene (C2-H4, ethene), a simple hydrocarbon gas that can function in plants as a growth regulator.	tmpzr1t_l9r_go_relaxed.owl	ethene binding													molecular_function											owl:Class	
GO:0072328	biolink:NamedThing	alkene binding	Binding to an alkene, any acyclic branched or unbranched hydrocarbon having one carbon-carbon double bond and the general formula CnH2n.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-11-02T12:39:40Z					molecular_function											owl:Class	
GO:0150007	biolink:NamedThing	clathrin-dependent synaptic vesicle endocytosis	Clathrin-dependent endocytosis of presynaptic membrane regions comprising synaptic vesicles' membrane constituents. This is a relatively slow process occurring in the range of tens of seconds.	tmpzr1t_l9r_go_relaxed.owl								bc	2017-12-01T10:11:35Z					biological_process											owl:Class	
GO:0072583	biolink:NamedThing	clathrin-dependent endocytosis	An endocytosis process that begins when material is taken up into clathrin-coated pits, which then pinch off to form clathrin-coated endocytic vesicles.	tmpzr1t_l9r_go_relaxed.owl	clathrin-mediated endocytosis|clathrin coated pit-dependent endocytosis|CME							mah	2011-02-08T03:59:18Z					biological_process											owl:Class	
GO:0001912	biolink:NamedThing	positive regulation of leukocyte mediated cytotoxicity	Any process that activates or increases the frequency, rate or extent of leukocyte mediated cytotoxicity.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of leukocyte mediated cytotoxicity|positive regulation of immune cell mediated cytotoxicity|activation of leukocyte mediated cytotoxicity|positive regulation of leucocyte mediated cytotoxicity|upregulation of leukocyte mediated cytotoxicity|stimulation of leukocyte mediated cytotoxicity|up regulation of leukocyte mediated cytotoxicity													biological_process											owl:Class	
GO:1901999	biolink:NamedThing	homogentisate metabolic process	The chemical reactions and pathways involving homogentisate.	tmpzr1t_l9r_go_relaxed.owl	homogentisate metabolism							tb	2013-03-21T00:01:02Z					biological_process											owl:Class	
GO:0090240	biolink:NamedThing	positive regulation of histone H4 acetylation	Any process that increases the rate, frequency, or extent of histone H4 acetylation, the modification of histone H4 by the addition of an acetyl group.	tmpzr1t_l9r_go_relaxed.owl								tb	2010-01-20T03:48:09Z					biological_process											owl:Class	
GO:1901792	biolink:NamedThing	3-(2,3-dihydroxyphenyl)propanoate biosynthetic process	The chemical reactions and pathways resulting in the formation of 3-(2,3-dihydroxyphenyl)propanoate.	tmpzr1t_l9r_go_relaxed.owl	3-(2,3-dihydroxyphenyl)propanoate synthesis|3-(2,3-dihydroxyphenyl)propanoate formation|3-(2,3-dihydroxyphenyl)propanoate anabolism|3-(2,3-dihydroxyphenyl)propanoate biosynthesis							yaf	2013-01-16T11:41:06Z					biological_process											owl:Class	
GO:0009713	biolink:NamedThing	catechol-containing compound biosynthetic process	The chemical reactions and pathways resulting in the formation of catechol-containing compounds. Catechol is a compound containing a pyrocatechol nucleus or substituent.	tmpzr1t_l9r_go_relaxed.owl	catechol biosynthesis|catechol biosynthetic process|catechol formation|catechol anabolism|catechol synthesis													biological_process											owl:Class	
GO:0010374	biolink:NamedThing	stomatal complex development	The process whose specific outcome is the progression of the stomatal complex over time from its formation to the mature structure. The stomatal complex is the stomatal guard cells and their associated epidermal cells.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0010443	biolink:NamedThing	meristemoid mother cell division	The asymmetric cell division by which a meristemoid mother cells (MMC) give rise to a meristemoid and another cell. The other cell may itself become a MMC or may generate an epidermal cell. Any cell that undergoes this type of division is a MMC.	tmpzr1t_l9r_go_relaxed.owl	meristemoid division													biological_process											owl:Class	
GO:0000911	biolink:NamedThing	cytokinesis by cell plate formation	The process of dividing the cytoplasm of a parent cell where a structure forms in the cytoplasm and grows until reaching the plasma membrane, thereby completely separating the cytoplasms of adjacent progeny cells. An example of this is found in Arabidopsis thaliana.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0033860	biolink:NamedThing	regulation of NAD(P)H oxidase activity	Any process that modulates the activity of the enzyme NAD(P)H oxidase.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0051341	biolink:NamedThing	regulation of oxidoreductase activity	Any process that modulates the frequency, rate or extent of oxidoreductase activity, the catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.	tmpzr1t_l9r_go_relaxed.owl	oxidoreductase regulator													biological_process											owl:Class	
GO:0048686	biolink:NamedThing	regulation of sprouting of injured axon	Any process that modulates the frequency, rate or extent of sprouting of an injured axon.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0022603	biolink:NamedThing	regulation of anatomical structure morphogenesis	Any process that modulates the frequency, rate or extent of anatomical structure morphogenesis.	tmpzr1t_l9r_go_relaxed.owl	regulation of morphogenesis													biological_process											owl:Class	
GO:0042832	biolink:NamedThing	defense response to protozoan	Reactions triggered in response to the presence of a protozoan that act to protect the cell or organism.	tmpzr1t_l9r_go_relaxed.owl	defence response to pathogenic protozoa|defence response to protozoa|resistance response to pathogenic protozoan|defence response to protozoon|defense response to protozoon|resistance response to pathogenic protozoa|defense response to pathogenic protozoa|defense response to protozoa|defense response to protozoan, incompatible interaction											GO:0009818		biological_process											owl:Class	
GO:0098542	biolink:NamedThing	defense response to other organism	Reactions triggered in response to the presence of another organism that act to protect the cell or organism from damage caused by that organism.	tmpzr1t_l9r_go_relaxed.owl	resistance response to pathogen|defense response, incompatible interaction|defence response incompatible interaction|defence response to pathogen, incompatible interaction	https://github.com/geneontology/go-ontology/issues/22173						dos	2013-11-11T12:59:11Z			GO:0009814		biological_process											owl:Class	
GO:0062248	biolink:NamedThing	cleistothecium formation	The process of producing a cleistothecium, a closed sexual fruiting body that contains ascospores in linear asci. Cleistothecia are present in some filamentous Ascomycete fungi such as members of the genera Aspergillus and Emericella.	tmpzr1t_l9r_go_relaxed.owl								dph	2020-05-08T16:14:06Z					biological_process											owl:Class	
GO:2000615	biolink:NamedThing	regulation of histone H3-K9 acetylation	Any process that modulates the frequency, rate or extent of histone H3-K9 acetylation.	tmpzr1t_l9r_go_relaxed.owl	regulation of histone H3K9 acetylation|regulation of histone H3 acetylation at K9							vk	2011-04-18T03:15:59Z					biological_process											owl:Class	
GO:0035065	biolink:NamedThing	regulation of histone acetylation	Any process that modulates the frequency, rate or extent of the addition of an acetyl group to a histone protein.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0061439	biolink:NamedThing	kidney vasculature morphogenesis	The process in which the kidney vasculature is generated and organized. Morphogenesis pertains to the creation of form.	tmpzr1t_l9r_go_relaxed.owl								dph	2012-03-08T12:30:11Z					biological_process											owl:Class	
GO:0030218	biolink:NamedThing	erythrocyte differentiation	The process in which a myeloid precursor cell acquires specializes features of an erythrocyte.	tmpzr1t_l9r_go_relaxed.owl	erythropoiesis|RBC differentiation|erythrocyte cell differentiation|red blood cell differentiation				Wikipedia:Erythropoiesis									biological_process											owl:Class	
GO:0030099	biolink:NamedThing	myeloid cell differentiation	The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of any cell of the myeloid leukocyte, megakaryocyte, thrombocyte, or erythrocyte lineages.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0106307	biolink:NamedThing	protein threonine phosphatase activity	Catalysis of the reaction: protein threonine phosphate + H2O = protein threonine + phosphate.	tmpzr1t_l9r_go_relaxed.owl					EC:3.1.3.16|RHEA:47004			hjd	2020-09-09T19:38:50Z					molecular_function											owl:Class	
GO:0004722	biolink:NamedThing	protein serine/threonine phosphatase activity	Catalysis of the reaction: protein serine phosphate + H2O = protein serine + phosphate, and protein threonine phosphate + H2O = protein threonine + phosphate.	tmpzr1t_l9r_go_relaxed.owl	casein phosphatase|phosphatase III|phosphopyruvate dehydrogenase phosphatase|protein phosphatase type 4 activity|polycation modulated (PCM-) phosphatase|phosphospectrin phosphatase|phosphatase SP|magnesium-dependent protein serine/threonine phosphatase activity|calcineurin|phosphatase C-II|protein phosphatase type 2A, intrinsic catalyst activity|phosphatase 2A|protein phosphatase X|phosphatase IV|phosphatase IB|phosphatase 2B|branched-chain alpha-keto acid dehydrogenase phosphatase|protein D phosphatase|protein phosphatase type 2C activity|phosphatase H-II|phosphatase I|protein phosphatase type 2A activity|BCKDH phosphatase|protein phosphatase type 1 activity|Aspergillus awamori acid protein phosphatase|protein phosphatase type 4, intrinsic catalyst activity|protein phosphatase type 2B, intrinsic catalyst activity|protein phosphatase type 2B activity|serine/threonine specific protein phosphatase activity|protein phosphatase type 1, intrinsic catalyst activity|HMG-CoA reductase phosphatase|phosphatase II|3-hydroxy 3-methylglutaryl coenzymeA reductase phosphatase				Reactome:R-HSA-2187401|Reactome:R-HSA-9619449|Reactome:R-HSA-5672961|Reactome:R-HSA-9660538|Reactome:R-HSA-9686524|Reactome:R-HSA-5683405|Reactome:R-HSA-5693153|Reactome:R-HSA-1638821|Reactome:R-HSA-4419948|Reactome:R-HSA-5675433|Reactome:R-HSA-5675431|Reactome:R-HSA-9660536|Reactome:R-HSA-5687758|Reactome:R-HSA-3002811|Reactome:R-HSA-6811504|Reactome:R-HSA-5694421|Reactome:R-HSA-4088141|Reactome:R-HSA-9619430|Reactome:R-HSA-2995388|EC:3.1.3.16|Reactome:R-HSA-8948139|Reactome:R-HSA-1295632|Reactome:R-HSA-429730|Reactome:R-HSA-3601585|Reactome:R-HSA-5679206|Reactome:R-HSA-201790|Reactome:R-HSA-74948|Reactome:R-HSA-9658445|Reactome:R-HSA-199425|Reactome:R-HSA-5672957|Reactome:R-HSA-5692754|Reactome:R-HSA-201787|Reactome:R-HSA-199959|Reactome:R-HSA-163568|Reactome:R-HSA-380949|Reactome:R-HSA-6792863|Reactome:R-HSA-9619467|Reactome:R-HSA-209055							GO:0030361|GO:0030358|GO:0015071|GO:0030357|GO:0008600|GO:0030360|GO:0000158|GO:0008598|GO:0000163|GO:0004724		molecular_function											owl:Class	
GO:0030747	biolink:NamedThing	indolepyruvate C-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + (indol-3-yl)pyruvate = S-adenosyl-L-homocysteine + (S)-3-(indol-3-yl)-2-oxobutanoate.	tmpzr1t_l9r_go_relaxed.owl	indolepyruvic acid methyltransferase activity|S-adenosyl-L-methionine:(indol-3-yl)pyruvate C-methyltransferase activity|S-adenosyl-L-methionine:indolepyruvate C-methyltransferase activity|indolepyruvate methyltransferase activity|indolepyruvate 3-methyltransferase activity				RHEA:12112|EC:2.1.1.47|MetaCyc:INDOLEPYRUVATE-C-METHYLTRANSFERASE-RXN									molecular_function											owl:Class	
GO:0008839	biolink:NamedThing	4-hydroxy-tetrahydrodipicolinate reductase	Catalysis of the reaction: (S)-2,3,4,5-tetrahydropyridine-2,6-dicarboxylate + NAD(P)+ + H2O = (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + NAD(P)H + H+.	tmpzr1t_l9r_go_relaxed.owl	dihydrodipicolinate reductase activity|dihydrodipicolinic acid reductase activity|2,3,4,5-tetrahydrodipicolinate:NAD(P)+ oxidoreductase activity				EC:1.17.1.8|MetaCyc:DIHYDROPICRED-RXN									molecular_function											owl:Class	
GO:0045709	biolink:NamedThing	negative regulation of adult salivary gland boundary specification	Any process that stops, prevents, or reduces the frequency, rate or extent of salivary gland determination in an adult organism.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of adult salivary gland determination|down regulation of adult salivary gland determination|downregulation of adult salivary gland determination|down-regulation of adult salivary gland determination|inhibition of adult salivary gland determination													biological_process											owl:Class	
GO:0045705	biolink:NamedThing	negative regulation of salivary gland boundary specification	Any process that stops, prevents, or reduces the frequency, rate or extent of salivary gland determination.	tmpzr1t_l9r_go_relaxed.owl	downregulation of salivary gland determination|inhibition of salivary gland determination|negative regulation of salivary gland determination|down regulation of salivary gland determination|down-regulation of salivary gland determination													biological_process											owl:Class	
GO:0010143	biolink:NamedThing	cutin biosynthetic process	The chemical reactions and pathways resulting in the formation of cutin, a waxy substance, which combined with cellulose forms a substance nearly impervious to water and constituting the cuticle in plants.	tmpzr1t_l9r_go_relaxed.owl	cutin anabolism|cutin biosynthesis|cutin formation|cutin synthesis				MetaCyc:PWY-321									biological_process											owl:Class	
GO:1901758	biolink:NamedThing	butirosin biosynthetic process	The chemical reactions and pathways resulting in the formation of butirosin.	tmpzr1t_l9r_go_relaxed.owl	butirosin synthesis|butirosin formation|butirosin biosynthesis|butirosin anabolism							yaf	2013-01-14T11:36:27Z					biological_process											owl:Class	
GO:0000376	biolink:NamedThing	RNA splicing, via transesterification reactions with guanosine as nucleophile	Splicing of RNA via a series of two transesterification reactions with exogenous guanosine as the initiating nucleophile.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0000375	biolink:NamedThing	RNA splicing, via transesterification reactions	Splicing of RNA via a series of two transesterification reactions.	tmpzr1t_l9r_go_relaxed.owl	spliceosomal catalysis|RNA splicing factor activity, transesterification mechanism|pre-mRNA splicing factor activity					Note that nuclear mRNA, Group I, Group II, and Group III introns are all spliced by a series of two transesterification reactions that occur within the RNA itself, or between two RNAs in trans splicing. Some of these require one or more proteins to stabilize the catalytic conformation, while others are autocatalytic. Note that tRNA introns are spliced by a different catalytic mechanism.						GO:0031202|GO:0000385		biological_process											owl:Class	
GO:0061045	biolink:NamedThing	negative regulation of wound healing	Any process that decreases the rate, frequency, or extent of the series of events that restore integrity to a damaged tissue, following an injury.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-02-25T10:33:30Z					biological_process											owl:Class	
GO:0033783	biolink:NamedThing	25-hydroxycholesterol 7alpha-hydroxylase activity	Catalysis of the reactions: cholest-5-ene-3beta,25-diol + NADPH + H+ + O2 = cholest-5-ene-3beta,7alpha,25-triol + NADP+ + H2O, and cholest-5-ene-3beta,27-diol + NADPH + H+ + O2 = cholest-5-ene-3beta,7alpha,27-triol + NADP+ + H2O.	tmpzr1t_l9r_go_relaxed.owl	CYP7B1|25-hydroxycholesterol 7alpha-monooxygenase activity|cholest-5-ene-3beta,25-diol,NADPH:oxygen oxidoreductase (7alpha-hydroxylating) activity|CYP7B1 oxysterol 7alpha-hydroxylase activity				MetaCyc:RXN-7981|EC:1.14.14.29|MetaCyc:RXN-7980|RHEA:19041									molecular_function											owl:Class	
GO:0043456	biolink:NamedThing	regulation of pentose-phosphate shunt	Any process that modulates the frequency, rate or extent of the pentose-phosphate shunt, the process in which glucose is oxidized, coupled to NADPH synthesis.	tmpzr1t_l9r_go_relaxed.owl	regulation of pentose-phosphate pathway|regulation of pentose phosphate shunt|regulation of pentose phosphate pathway													biological_process											owl:Class	
GO:0031117	biolink:NamedThing	positive regulation of microtubule depolymerization	Any process that activates or increases the frequency, rate or extent of microtubule depolymerization.	tmpzr1t_l9r_go_relaxed.owl	stimulation of microtubule depolymerization|positive regulation of microtubule disassembly|positive regulation of microtubule catastrophe|upregulation of microtubule depolymerization|microtubule destabilization|up-regulation of microtubule depolymerization|up regulation of microtubule depolymerization|activation of microtubule depolymerization													biological_process											owl:Class	
GO:0031114	biolink:NamedThing	regulation of microtubule depolymerization	Any process that modulates the frequency, rate or extent of microtubule depolymerization.	tmpzr1t_l9r_go_relaxed.owl	regulation of microtubule disassembly													biological_process											owl:Class	
GO:0031798	biolink:NamedThing	type 1 metabotropic glutamate receptor binding	Binding to a type 1 metabotropic glutamate receptor.	tmpzr1t_l9r_go_relaxed.owl	type 1 metabotropic glutamate receptor ligand													molecular_function											owl:Class	
GO:0035256	biolink:NamedThing	G protein-coupled glutamate receptor binding	Binding to a G protein-coupled glutamate receptor (a metabotropic glutamate receptor).	tmpzr1t_l9r_go_relaxed.owl	metabotropic glutamate receptor binding|G-protein coupled glutamate receptor binding													molecular_function											owl:Class	
GO:1902867	biolink:NamedThing	negative regulation of retina development in camera-type eye	Any process that stops, prevents or reduces the frequency, rate or extent of retina development in camera-type eye.	tmpzr1t_l9r_go_relaxed.owl	down regulation of retina development in camera-type eye|down-regulation of retina development in camera-type eye|down-regulation of retinal development|inhibition of retina development in camera-type eye|inhibition of retinal development|inhibition of retina development in camera-style eye|down-regulation of retina development in camera-style eye|downregulation of retinal development|downregulation of retina development in camera-style eye|negative regulation of retina development in camera-style eye|negative regulation of retinal development|down regulation of retina development in camera-style eye|downregulation of retina development in camera-type eye|down regulation of retinal development							mr	2014-04-03T15:24:23Z					biological_process											owl:Class	
GO:0060372	biolink:NamedThing	regulation of atrial cardiac muscle cell membrane repolarization	Any process that modulates the establishment or extent of a membrane potential in the polarizing direction towards the resting potential in an atrial cardiomyocyte.	tmpzr1t_l9r_go_relaxed.owl	regulation of atrial cardiac muscle cell repolarization|regulation of atrial cardiomyocyte membrane repolarization|atrial repolarization|electrocardiogram QRS complex													biological_process											owl:Class	
GO:0099623	biolink:NamedThing	regulation of cardiac muscle cell membrane repolarization	Any process that modulates the establishment or extent of a change in membrane potential in the polarizing direction towards the resting potential in a cardiomyocyte.	tmpzr1t_l9r_go_relaxed.owl	regulation of cardiac muscle cell repolarization|heart repolarization|regulation of cardiomyocyte membrane repolarization													biological_process											owl:Class	
GO:0060215	biolink:NamedThing	primitive hemopoiesis	A first transient wave of blood cell production that, in vertebrates, gives rise to erythrocytes (red blood cells) and myeloid cells.	tmpzr1t_l9r_go_relaxed.owl	primitive haemopoiesis|primitive haematopoiesis|primitive hematopoiesis													biological_process											owl:Class	
GO:0009848	biolink:NamedThing	indoleacetic acid biosynthetic process via tryptophan	The chemical reactions and pathways resulting in the formation of indole-3-acetic acid that occurs through metabolism of L-tryptophan.	tmpzr1t_l9r_go_relaxed.owl	indoleacetic acid formation via tryptophan|indoleacetic acid synthesis via tryptophan|indoleacetic acid anabolism via tryptophan|IAA biosynthetic process via tryptophan				MetaCyc:PWY-581									biological_process											owl:Class	
GO:0009684	biolink:NamedThing	indoleacetic acid biosynthetic process	The chemical reactions and pathways resulting in the formation of indole-3-acetic acid, a compound which functions as a growth regulator in plants.	tmpzr1t_l9r_go_relaxed.owl	indole acetic acid biosynthesis|indoleacetic acid anabolism|indole acetic acid biosynthetic process|indoleacetic acid biosynthesis|indole-acetic acid biosynthetic process|indole-3-acetate biosynthesis|indoleacetic acid formation|indoleacetic acid synthesis|IAA biosynthetic process|indole-acetic acid biosynthesis|indole-3-acetate biosynthetic process													biological_process											owl:Class	
GO:1901114	biolink:NamedThing	erythromycin catabolic process	The chemical reactions and pathways resulting in the breakdown of erythromycin.	tmpzr1t_l9r_go_relaxed.owl	erythromycin degradation|erythromycin catabolism|erythromycin breakdown							yaf	2012-07-11T03:06:38Z					biological_process											owl:Class	
GO:1901113	biolink:NamedThing	erythromycin metabolic process	The chemical reactions and pathways involving erythromycin.	tmpzr1t_l9r_go_relaxed.owl	erythromycin metabolism							yaf	2012-07-11T03:06:13Z					biological_process											owl:Class	
GO:0048508	biolink:NamedThing	embryonic meristem development	The process whose specific outcome is the progression of the embryonic meristem over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0048507	biolink:NamedThing	meristem development	The process whose specific outcome is the progression of the meristem over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0034755	biolink:NamedThing	iron ion transmembrane transport	A process in which an iron ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	transmembrane iron transport|ferrous ion transmembrane transport|iron(2+) transmembrane transport|low-affinity iron ion transmembrane transport|ferrous iron transmembrane transport|high-affinity iron ion transmembrane transport|low affinity iron ion transport|high-affinity iron ion transport|iron ion membrane transport|high-affinity ferrous ion transmembrane transport|low-affinity iron ion transport|high affinity ferrous ion transmembrane transport|high affinity iron ion transport					Note that this term is not intended for use in annotating lateral movement within membranes.		vw	2015-02-06T11:29:22Z			GO:1903874|GO:0000040|GO:0061839|GO:0006827		biological_process											owl:Class	
GO:0098662	biolink:NamedThing	inorganic cation transmembrane transport	A process in which an inorganic cation is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	divalent inorganic cation transport|monovalent inorganic cation transport|transmembrane inorganic cation transport|inorganic cation membrane transport					Note that this term is not intended for use in annotating lateral movement within membranes.						GO:0072511|GO:0015672		biological_process											owl:Class	
GO:0035291	biolink:NamedThing	specification of segmental identity, intercalary segment	The specification of the characteristic structures of the intercalary segment of the anterior head, following establishment of segment boundaries. Identity is considered to be the aggregate of characteristics by which a structure is recognized.	tmpzr1t_l9r_go_relaxed.owl						See also the fly_anatomy.ontology term 'intercalary segment ; FBbt:00000010'.								biological_process											owl:Class	
GO:0007380	biolink:NamedThing	specification of segmental identity, head	The specification of the characteristic structures of the head segments following establishment of segment boundaries. Identity is considered to be the aggregate of characteristics by which a structure is recognized.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0050769	biolink:NamedThing	positive regulation of neurogenesis	Any process that activates or increases the frequency, rate or extent of neurogenesis, the generation of cells within the nervous system.	tmpzr1t_l9r_go_relaxed.owl	up regulation of neurogenesis|stimulation of neurogenesis|upregulation of neurogenesis|up-regulation of neurogenesis|activation of neurogenesis													biological_process											owl:Class	
GO:1903408	biolink:NamedThing	positive regulation of P-type sodium:potassium-exchanging transporter activity	Any process that activates or increases the frequency, rate or extent of sodium:potassium-exchanging ATPase activity.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of sodium/potassium-exchanging ATPase activity|upregulation of ATP phosphohydrolase (Na+/K+-exchanging)|positive regulation of (Na+ + K+)-ATPase activity|positive regulation of (Na+ + K+)-activated ATPase activity|positive regulation of Na+/K+-ATPase activity|up-regulation of (Na+ + K+)-activated ATPase activity|positive regulation of Na+,K+ pump|activation of ATP phosphohydrolase (Na+/K+-exchanging)|positive regulation of Na(+)/K(+)-ATPase activity|up-regulation of sodium:potassium exchanging ATPase activity|up regulation of Na+/K+-exchanging ATPase activity|up-regulation of (Na+ + K+)-ATPase activity|up regulation of (Na+ + K+)-activated ATPase activity|activation of Na(+)/K(+)-exchanging ATPase activity|upregulation of Na+/K+-ATPase activity|upregulation of Na(+)/K(+)-exchanging ATPase activity|upregulation of Na,K-activated ATPase activity|upregulation of sodium:potassium-exchanging ATPase activity|up regulation of Na+/K+-ATPase activity|upregulation of sodium/potassium-transporting ATPase activity|up-regulation of ATP phosphohydrolase (Na+/K+-exchanging)|up regulation of Na(+)/K(+)-ATPase activity|up regulation of sodium:potassium exchanging ATPase activity|up regulation of sodium/potassium-exchanging ATPase activity|upregulation of sodium:potassium exchanging ATPase activity|up-regulation of Na+/K+-exchanging ATPase activity|activation of Na+/K+-ATPase activity|up-regulation of Na+,K+ pump|up-regulation of Na(+)/K(+)-ATPase activity|up regulation of Na,K-activated ATPase activity|activation of sodium/potassium-transporting ATPase activity|activation of (Na+ + K+)-ATPase activity|positive regulation of sodium/potassium-exchanging ATPase activity|activation of Na(+)/K(+)-ATPase activity|upregulation of Na+,K+ pump|activation of Na,K-activated ATPase activity|upregulation of Na,K-pump|up regulation of (Na+ + K+)-ATPase activity|up regulation of ATP phosphohydrolase (Na+/K+-exchanging)|positive regulation of ATP phosphohydrolase (Na+/K+-exchanging)|up-regulation of sodium:potassium-exchanging ATPase activity|upregulation of Na+/K+-exchanging ATPase activity|positive regulation of Na+/K+-exchanging ATPase activity|positive regulation of Na+,K+-ATPase activity|activation of Na+/K+-exchanging ATPase activity|up-regulation of Na,K-pump|activation of Na,K-pump|upregulation of Na(+)/K(+)-ATPase activity|up regulation of Na,K-pump|up-regulation of Na,K-activated ATPase activity|upregulation of (Na+ + K+)-activated ATPase activity|up-regulation of Na+,K+-ATPase activity|positive regulation of sodium:potassium-exchanging ATPase activity|up regulation of sodium/potassium-transporting ATPase activity|positive regulation of Na,K-activated ATPase activity|activation of sodium/potassium-exchanging ATPase activity|upregulation of (Na+ + K+)-ATPase activity|up-regulation of sodium/potassium-transporting ATPase activity|up-regulation of Na(+)/K(+)-exchanging ATPase activity|upregulation of sodium/potassium-exchanging ATPase activity|up regulation of Na+,K+-ATPase activity|up regulation of sodium:potassium-exchanging ATPase activity|activation of (Na+ + K+)-activated ATPase activity|positive regulation of sodium:potassium exchanging ATPase activity|upregulation of Na+,K+-ATPase activity|activation of sodium:potassium-exchanging ATPase activity|up-regulation of Na+/K+-ATPase activity|activation of Na+,K+ pump|up regulation of Na(+)/K(+)-exchanging ATPase activity|up regulation of Na+,K+ pump|positive regulation of sodium/potassium-transporting ATPase activity|activation of sodium:potassium exchanging ATPase activity|positive regulation of Na(+)/K(+)-exchanging ATPase activity|activation of Na+,K+-ATPase activity|positive regulation of Na,K-pump							mr	2014-09-02T19:45:24Z					biological_process											owl:Class	
GO:0032781	biolink:NamedThing	positive regulation of ATP-dependent activity	Any process that activates or increases the rate of an ATP-dependent activity.	tmpzr1t_l9r_go_relaxed.owl	up regulation of ATPase activity|activation of ATPase activity|stimulation of ATPase activity|positive regulation of ATPase activity|upregulation of ATPase activity|up-regulation of ATPase activity|positive regulation of adenosinetriphosphatase activity	https://github.com/geneontology/go-ontology/issues/22371												biological_process											owl:Class	
GO:0018544	biolink:NamedThing	4-carboxy-4'-sulfoazobenzene reductase activity	Catalysis of the reaction: 4-carboxy-4'-sulfoazobenzene + 4 H+ + 4 e- = 4-aminobenzoate + 4-aminobenzenesulfonate.	tmpzr1t_l9r_go_relaxed.owl	4-carboxy-4'-sulphoazobenzene reductase activity				UM-BBD_reactionID:r0543									molecular_function											owl:Class	
GO:0016657	biolink:NamedThing	oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces a nitrogenous group.	tmpzr1t_l9r_go_relaxed.owl	oxidoreductase activity, acting on NADH or NADPH, nitrogenous group as acceptor				EC:1.6.6.-									molecular_function											owl:Class	
GO:0001581	biolink:NamedThing	detection of chemical stimulus involved in sensory perception of sour taste	The series of events required for a sour taste stimulus to be received and converted to a molecular signal.	tmpzr1t_l9r_go_relaxed.owl	perception of sour taste, sensory transduction of chemical stimulus|sour taste detection|sensory detection of chemical stimulus during perception of sour taste|sensory detection of sour taste|sensory transduction of sour taste|perception of sour taste, detection of chemical stimulus|sensory transduction of chemical stimulus during perception of sour taste													biological_process											owl:Class	
GO:0050912	biolink:NamedThing	detection of chemical stimulus involved in sensory perception of taste	The series of events involved in the perception of taste in which a gustatory chemical stimulus is received and converted into a molecular signal.	tmpzr1t_l9r_go_relaxed.owl	perception of taste, sensory transduction of chemical stimulus|sensory detection of taste|taste perception|sensory transduction of taste|sensory transduction of chemical stimulus during perception of taste|perception of taste, sensory detection of chemical stimulus|sensory detection of chemical stimulus during perception of taste|perception of taste, detection of chemical stimulus													biological_process											owl:Class	
GO:2001007	biolink:NamedThing	negative regulation of cellulose biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of cellulose biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of cellulose formation|negative regulation of cellulose biosynthesis|negative regulation of cellulose anabolism|negative regulation of cellulose synthesis							tt	2011-08-08T08:42:24Z					biological_process											owl:Class	
GO:0070727	biolink:NamedThing	cellular macromolecule localization	Any process in which a macromolecule is transported to, and/or maintained in, a specific location at the level of a cell. Localization at the cellular level encompasses movement within the cell, from within the cell to the cell surface, or from one location to another at the surface of a cell.	tmpzr1t_l9r_go_relaxed.owl	cellular macromolecule localisation							mah	2009-06-16T04:08:29Z					biological_process											owl:Class	
GO:0033036	biolink:NamedThing	macromolecule localization	Any process in which a macromolecule is transported to, or maintained in, a specific location.	tmpzr1t_l9r_go_relaxed.owl	macromolecule localisation													biological_process											owl:Class	
GO:0030519	biolink:NamedThing	snoRNP binding	Binding to a small nucleolar ribonucleoprotein particle.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0043021	biolink:NamedThing	ribonucleoprotein complex binding	Binding to a complex of RNA and protein.	tmpzr1t_l9r_go_relaxed.owl	ribonucleoprotein binding|RNP binding|protein-RNA complex binding													molecular_function											owl:Class	
GO:0018160	biolink:NamedThing	peptidyl-pyrromethane cofactor linkage	The covalent binding of a pyrromethane (dipyrrin) cofactor to protein via the sulfur atom of cysteine forming dipyrrolylmethanemethyl-L-cysteine.	tmpzr1t_l9r_go_relaxed.owl	peptidyl-pyrromethane cofactor linkage via dipyrrolylmethanemethyl-L-cysteine|dipyrromethane cofactor binding				RESID:AA0252							GO:0033035|GO:0018354		biological_process											owl:Class	
GO:0030639	biolink:NamedThing	polyketide biosynthetic process	The chemical reactions and pathways resulting in the formation of polyketides, any of a diverse group of natural products synthesized via linear poly-beta-ketones, which are themselves formed by repetitive head-to-tail addition of acetyl (or substituted acetyl) units indirectly derived from acetate (or a substituted acetate) by a mechanism similar to that for fatty acid biosynthesis but without the intermediate reductive steps.	tmpzr1t_l9r_go_relaxed.owl	polyketide synthesis|polyketide anabolism|polyketide biosynthesis|polyketide formation													biological_process											owl:Class	
GO:0044550	biolink:NamedThing	secondary metabolite biosynthetic process	The chemical reactions and pathways resulting in the formation of secondary metabolites, the compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon.	tmpzr1t_l9r_go_relaxed.owl	secondary metabolite biosynthesis							jl	2012-03-29T01:55:18Z					biological_process											owl:Class	
GO:1903670	biolink:NamedThing	regulation of sprouting angiogenesis	Any process that modulates the frequency, rate or extent of sprouting angiogenesis.	tmpzr1t_l9r_go_relaxed.owl								pga	2014-11-27T10:10:51Z					biological_process											owl:Class	
GO:1901420	biolink:NamedThing	negative regulation of response to alcohol	Any process that stops, prevents or reduces the frequency, rate or extent of response to alcohol.	tmpzr1t_l9r_go_relaxed.owl	downregulation of response to alcohol|down regulation of response to alcohol|inhibition of response to alcohol|down-regulation of response to alcohol							tt	2012-10-01T16:53:25Z					biological_process											owl:Class	
GO:1901419	biolink:NamedThing	regulation of response to alcohol	Any process that modulates the frequency, rate or extent of response to alcohol.	tmpzr1t_l9r_go_relaxed.owl								tt	2012-10-01T16:52:13Z					biological_process											owl:Class	
GO:0002893	biolink:NamedThing	negative regulation of type II hypersensitivity	Any process that stops, prevents, or reduces the frequency, rate, or extent of type II hypersensitivity.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of type II hypersensitivity|inhibition of type II hypersensitivity|downregulation of type II hypersensitivity|down regulation of type II hypersensitivity													biological_process											owl:Class	
GO:0002892	biolink:NamedThing	regulation of type II hypersensitivity	Any process that modulates the frequency, rate, or extent of type II hypersensitivity.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0018245	biolink:NamedThing	protein O-linked glycosylation via tyrosine	The glycosylation of protein via the O4' atom of peptidyl-tyrosine, O4'-glycosyl-L-tyrosine; the carbohydrate is glucose, the origin for glycogen.	tmpzr1t_l9r_go_relaxed.owl	protein amino acid O-linked glycosylation via tyrosine				RESID:AA0157									biological_process											owl:Class	
GO:0036498	biolink:NamedThing	IRE1-mediated unfolded protein response	A series of molecular signals mediated by the endoplasmic reticulum stress sensor IRE1 (Inositol-requiring transmembrane kinase/endonuclease). Begins with activation of IRE1 in response to endoplasmic reticulum (ER) stress, and ends with regulation of a downstream cellular process, e.g. transcription. One target of activated IRE1 is the transcription factor HAC1 in yeast, or XBP1 in mammals; IRE1 cleaves an intron of a mRNA coding for HAC1/XBP1 to generate an activated HAC1/XBP1 transcription factor, which controls the up regulation of UPR-related genes. At least in mammals, IRE1 can also signal through additional intracellular pathways including JNK and NF-kappaB.	tmpzr1t_l9r_go_relaxed.owl	endoplasmic reticulum unfolded protein response; IRE1 signaling|IRE1alpha unfolded protein response|IRE1 signaling in response to endoplasmic reticulum stress|ERN1-mediated unfolded protein response|UPR signaling by IRE1 stress sensor|inositol-requiring transmembrane kinase/endonuclease signal transduction|IRE1p unfolded protein response|inositol-requiring enzyme 1-mediated unfolded protein response|IRE1 signal transduction pathway|IRE1 branch of UPR					Consider also annotating to 'eiF2alpha phosphorylation in response to endoplasmic reticulum stress ; GO:0036492' or its descendants.		bf	2015-02-05T13:12:12Z					biological_process											owl:Class	
GO:0030968	biolink:NamedThing	endoplasmic reticulum unfolded protein response	The series of molecular signals generated as a consequence of the presence of unfolded proteins in the endoplasmic reticulum (ER) or other ER-related stress; results in changes in the regulation of transcription and translation.	tmpzr1t_l9r_go_relaxed.owl	erUPR|SREBP-mediated signalling pathway|ER unfolded protein response					Note that this term should not be confused with 'response to unfolded protein ; GO:0006986', which refers to any response to the presence of unfolded proteins anywhere in the cell or in multicellular organism. Also see 'ER-associated protein catabolic process ; GO:0030433'.								biological_process											owl:Class	
GO:0046792	biolink:NamedThing	suppression by virus of host cell cycle arrest	Viral interference in host cell processes that lead cell cycle arrest, allowing cell division to occur.	tmpzr1t_l9r_go_relaxed.owl	negative regulation by virus of cell cycle arrest|viral inhibition of cell cycle arrest													biological_process											owl:Class	
GO:0019055	biolink:NamedThing	modification by virus of host cell cycle regulation	Interactions, directly with the host cell macromolecular machinery, to allow a virus to modulate the rate of the host cell cycle to facilitate virus replication.	tmpzr1t_l9r_go_relaxed.owl	viral perturbation of cell cycle regulation													biological_process											owl:Class	
GO:0034320	biolink:NamedThing	alcohol O-hexanoyltransferase activity	Catalysis of the reaction: hexanoyl-CoA + an alcohol = CoA + a hexyl ester.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0034318	biolink:NamedThing	alcohol O-acyltransferase activity	Catalysis of the transfer of an acyl group to an oxygen atom on an alcohol acceptor molecule.	tmpzr1t_l9r_go_relaxed.owl	alcohol acyltransferase activity|AEATase activity|acyl-CoA:ethanol O-acyltransferase|acyl-coenzymeA:ethanol O-acyltransferase activity|acyl-coenzymeA:alcohol O-acyltransferase activity|acyl-CoA:alcohol O-acyltransferase activity													molecular_function											owl:Class	
GO:0052904	biolink:NamedThing	N1-acetylspermidine:oxygen oxidoreductase (3-acetamidopropanal-forming) activity	Catalysis of the reaction: H(2)O + N(1)-acetylspermidine + O(2) = 3-acetamidopropanal + H(2)O(2) + putrescine.	tmpzr1t_l9r_go_relaxed.owl	non-specific polyamine oxidase activity|N(1)-acetylpolyamine oxidase activity|polyamine oxidase activity				RHEA:25812|KEGG_REACTION:R09074|MetaCyc:RXN-12091|Reactome:R-HSA-141351|EC:1.5.3.17|MetaCyc:RXN-9942|Reactome:R-HSA-141348|EC:1.5.3.13									molecular_function											owl:Class	
GO:0047007	biolink:NamedThing	pregnan-21-ol dehydrogenase (NAD+) activity	Catalysis of the reaction: NAD(+) + pregnan-21-ol = H(+) + NADH + pregnan-21-al.	tmpzr1t_l9r_go_relaxed.owl	21-hydroxysteroid:NAD+ 21-oxidoreductase activity|21-hydroxysteroid dehydrogenase (NAD+) activity				RHEA:11448|KEGG_REACTION:R03043|EC:1.1.1.150|MetaCyc:1.1.1.150-RXN									molecular_function											owl:Class	
GO:0033764	biolink:NamedThing	steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces NAD+ or NADP, and in which one substrate is a sterol derivative.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1900975	biolink:NamedThing	negative regulation of tatiopterin biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of tatiopterin biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of tatiopterin biosynthesis|down regulation of tatiopterin formation|down regulation of tatiopterin synthesis|down regulation of tatiopterin anabolism|down-regulation of tatiopterin formation|down regulation of tatiopterin biosynthetic process|down-regulation of tatiopterin biosynthetic process|inhibition of tatiopterin anabolism|downregulation of tatiopterin synthesis|inhibition of tatiopterin biosynthetic process|inhibition of tatiopterin biosynthesis|inhibition of tatiopterin formation|downregulation of tatiopterin biosynthetic process|inhibition of tatiopterin synthesis|down-regulation of tatiopterin biosynthesis|down regulation of tatiopterin biosynthesis|down-regulation of tatiopterin anabolism|downregulation of tatiopterin formation|down-regulation of tatiopterin synthesis|negative regulation of tatiopterin formation|downregulation of tatiopterin anabolism|negative regulation of tatiopterin anabolism|negative regulation of tatiopterin synthesis|downregulation of tatiopterin biosynthesis							tt	2012-06-14T04:02:06Z					biological_process											owl:Class	
GO:1900974	biolink:NamedThing	regulation of tatiopterin biosynthetic process	Any process that modulates the frequency, rate or extent of tatiopterin biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of tatiopterin anabolism|regulation of tatiopterin synthesis|regulation of tatiopterin biosynthesis|regulation of tatiopterin formation							tt	2012-06-14T04:01:42Z					biological_process											owl:Class	
GO:0014008	biolink:NamedThing	positive regulation of microglia differentiation	Any process that activates, maintains or increases the frequency, rate or extent of microglia differentiation, the process in which a relatively unspecialized cell acquires specialized features of a microglial cell.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of microglia differentiation|upregulation of microglia differentiation|activation of microglia differentiation|up regulation of microglia differentiation|positive regulation of microglial cell differentiation|stimulation of microglia differentiation													biological_process											owl:Class	
GO:0014006	biolink:NamedThing	regulation of microglia differentiation	Any process that modulates the frequency, rate or extent of microglia differentiation, the process in which a relatively unspecialized cell acquires specialized features of a microglial cell.	tmpzr1t_l9r_go_relaxed.owl	regulation of microglial cell differentiation													biological_process											owl:Class	
GO:0010668	biolink:NamedThing	ectodermal cell differentiation	The process in which relatively unspecialized cells acquire specialized structural and/or functional features of an ectodermal cell. Differentiation includes the processes involved in commitment of a cell to a specific fate.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0075055	biolink:NamedThing	positive regulation of penetration peg formation	Any process that activates, maintains or increases the frequency, rate or extent of symbiont penetration peg formation for entry into host. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of symbiont penetration peg formation for entry into host|positive regulation of symbiont penetration peg initiation	https://github.com/geneontology/go-ontology/issues/18557				Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products from the symbiont involved in this process.						GO:0075059		biological_process											owl:Class	
GO:0075054	biolink:NamedThing	modulation of penetration peg formation	Any process that modulates the frequency, rate or extent of symbiont penetration peg formation for entry into host. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	modulation of symbiont penetration peg initiation|modulation of symbiont penetration peg formation for entry into host	https://github.com/geneontology/go-ontology/issues/18557				Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products from the symbiont involved in this process.						GO:0075058		biological_process											owl:Class	
GO:1904669	biolink:NamedThing	ATP export	The directed movement of ATP out of a cell or organelle.	tmpzr1t_l9r_go_relaxed.owl	ATP efflux							tb	2015-09-09T16:33:06Z					biological_process											owl:Class	
GO:0015867	biolink:NamedThing	ATP transport	The directed movement of ATP, adenosine triphosphate, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0106081	biolink:NamedThing	maltose import across plasma membrane	The directed movement of maltose from outside of a cell, across the plasma membrane and into the cytosol.	tmpzr1t_l9r_go_relaxed.owl								hjd	2017-12-28T18:14:16Z					biological_process											owl:Class	
GO:1904981	biolink:NamedThing	maltose transmembrane transport	The process in which maltose is transported across a membrane.	tmpzr1t_l9r_go_relaxed.owl								vw	2016-02-28T21:14:04Z					biological_process											owl:Class	
GO:1990299	biolink:NamedThing	Bub1-Bub3 complex localization to kinetochore	A cellular protein complex localization that acts on a Bub1-Bub3 complex; as a result, the complex is transported to, or maintained in, a specific location at the kinetochore.	tmpzr1t_l9r_go_relaxed.owl								al	2014-02-26T09:29:13Z					biological_process											owl:Class	
GO:2000702	biolink:NamedThing	regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation	Any process that modulates the frequency, rate or extent of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation.	tmpzr1t_l9r_go_relaxed.owl	regulation of fibroblast growth factor receptor signaling pathway of ureteric bud formation|regulation of FGF receptor signaling pathway of ureteric bud formation|regulation of fibroblast growth factor receptor signalling pathway of ureteric bud formation|regulation of FGFR signaling pathway of ureteric bud formation|regulation of FGF receptor signalling pathway of ureteric bud formation							yaf	2011-05-25T09:48:15Z					biological_process											owl:Class	
GO:0044084	biolink:NamedThing	host cell membrane pore complex	Any small opening in a host cell membrane that allows the passage of gases and/or liquids, composed of host proteins.	tmpzr1t_l9r_go_relaxed.owl	pore complex in host cell membrane													cellular_component											owl:Class	
GO:0046107	biolink:NamedThing	uracil biosynthetic process	The chemical reactions and pathways resulting in the formation of uracil, 2,4-dioxopyrimidine, one of the pyrimidine bases occurring in RNA, but not in DNA.	tmpzr1t_l9r_go_relaxed.owl	uracil anabolism|uracil synthesis|uracil formation|uracil biosynthesis													biological_process											owl:Class	
GO:0019856	biolink:NamedThing	pyrimidine nucleobase biosynthetic process	The chemical reactions and pathways resulting in the formation of pyrimidine nucleobases, 1,3-diazine, organic nitrogenous bases.	tmpzr1t_l9r_go_relaxed.owl	pyrimidine base biosynthesis|pyrimidine base anabolism|pyrimidine base formation|pyrimidine base synthesis|pyrimidine base biosynthetic process													biological_process											owl:Class	
GO:1990923	biolink:NamedThing	PET complex	A protein complex that is composed of at least EXD1, TDRD12 and some PIWI protein. The complex is required for MILI slicing-triggered biogenesis and loading of MIWI2 piRNAs.	tmpzr1t_l9r_go_relaxed.owl								sp	2016-01-14T02:19:39Z					cellular_component											owl:Class	
GO:0047430	biolink:NamedThing	oligosaccharide-diphosphodolichol diphosphatase activity	Catalysis of the reaction: H2O + oligosaccharide-diphosphodolichol = dolichol-phosphate + oligosaccharide phosphate.	tmpzr1t_l9r_go_relaxed.owl	oligosaccharide-diphosphodolichol phosphodolichohydrolase activity|oligosaccharide-diphosphodolichol pyrophosphatase activity				MetaCyc:3.6.1.44-RXN|RHEA:15205|EC:3.6.1.44									molecular_function											owl:Class	
GO:0070955	biolink:NamedThing	negative regulation of neutrophil mediated killing of symbiont cell	Any process that decreases the frequency, rate or extent of the directed killing of a symbiont target cell by a neutrophil.	tmpzr1t_l9r_go_relaxed.owl	downregulation of neutrophil mediated killing of symbiont cell|down-regulation of neutrophil mediated killing of symbiont cell|inhibition of neutrophil mediated killing of symbiont cell|down regulation of neutrophil mediated killing of symbiont cell							mah	2009-10-01T02:20:17Z					biological_process											owl:Class	
GO:0033713	biolink:NamedThing	choline:oxygen 1-oxidoreductase activity	Catalysis of the reaction: choline + O2 = betaine aldehyde + hydrogen peroxide.	tmpzr1t_l9r_go_relaxed.owl	choline oxidase activity				MetaCyc:CHOLINE-OXIDASE-RXN|EC:1.1.3.17|RHEA:13505									molecular_function											owl:Class	
GO:0016899	biolink:NamedThing	oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces an oxygen molecule.	tmpzr1t_l9r_go_relaxed.owl					EC:1.1.3.-									molecular_function											owl:Class	
GO:0042631	biolink:NamedThing	cellular response to water deprivation	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of water.	tmpzr1t_l9r_go_relaxed.owl	cellular response to drought													biological_process											owl:Class	
GO:0071462	biolink:NamedThing	cellular response to water stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of water.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-12-18T11:32:44Z					biological_process											owl:Class	
GO:0098789	biolink:NamedThing	pre-mRNA cleavage required for polyadenylation	The targeted, endonucleolytic cleavage of a pre-mRNA,  required for polyadenylation of the 3' end.  This cleavage is directed by binding sites near the 3' end of the mRNA and leaves a 3' hydoxyl end which then becomes a target for adenylation.	tmpzr1t_l9r_go_relaxed.owl	pre-mRNA cleavage factor activity|cleavage and polyadenylylation specificity factor activity													biological_process											owl:Class	
GO:0098787	biolink:NamedThing	mRNA cleavage involved in mRNA processing	Cleavage of an immature mRNA transcript to produce one or more more mature mRNA transcripts, prior to translation into polypeptide.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0043334	biolink:NamedThing	2-hexaprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity	Catalysis of the reaction: 2-hexaprenyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-methionine = 2-hexaprenyl-3-methyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-homocysteine.	tmpzr1t_l9r_go_relaxed.owl	2-hexaprenyl-6-methoxy-1,4-benzoquinone methylase activity					Note that the polyprenyl sidechain substrate for these methyltransferases varies in length between species, for example, 6 units in S. cerevisiae, 8 units in E. coli and 10 units in G. suboxidans. Where the length of the substrate polyprenyl chain is unknown, the term '2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity ; GO:0008425' should be used.								molecular_function											owl:Class	
GO:0008425	biolink:NamedThing	2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity	Catalysis of the reaction: 2-polyprenyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-methionine = 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-homocysteine.	tmpzr1t_l9r_go_relaxed.owl	coenzyme Q biosynthetic process methyltransferase activity|2-polyprenyl-6-methoxy-1,4-benzoquinone methylase activity|coenzyme Q biosynthesis methyltransferase activity|ubiquinone biosynthetic process methyltransferase activity|ubiquinone biosynthesis methyltransferase activity				EC:2.1.1.-									molecular_function											owl:Class	
GO:0004585	biolink:NamedThing	ornithine carbamoyltransferase activity	Catalysis of the reaction: carbamoyl phosphate + L-ornithine = phosphate + L-citrulline.	tmpzr1t_l9r_go_relaxed.owl	OTCase activity|carbamoyl-phosphate:L-ornithine carbamoyltransferase activity|L-ornithine transcarbamylase activity|L-ornithine carbamoyltransferase activity|ornithine transcarbamylase activity|L-ornithine carbamyltransferase activity|carbamylphosphate-ornithine transcarbamylase activity|OTC activity|citrulline phosphorylase activity|ornithine carbamyltransferase activity				Reactome:R-HSA-70560|MetaCyc:RXN-13482|MetaCyc:ORNCARBAMTRANSFER-RXN|RHEA:19513|EC:2.1.3.3									molecular_function											owl:Class	
GO:0016743	biolink:NamedThing	carboxyl- or carbamoyltransferase activity	Catalysis of the transfer of a carboxyl- or carbamoyl group from one compound (donor) to another (acceptor).	tmpzr1t_l9r_go_relaxed.owl	carboxyl- and carbamoyltransferase activity				EC:2.1.3.-									molecular_function											owl:Class	
GO:0071378	biolink:NamedThing	cellular response to growth hormone stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth hormone stimulus. Growth hormone is a peptide hormone that binds to the growth hormone receptor and stimulates growth.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-12-11T03:25:17Z					biological_process											owl:Class	
GO:0060416	biolink:NamedThing	response to growth hormone	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth hormone stimulus. Growth hormone is a peptide hormone that binds to the growth hormone receptor and stimulates growth.	tmpzr1t_l9r_go_relaxed.owl	response to growth hormone stimulus													biological_process											owl:Class	
GO:0043107	biolink:NamedThing	type IV pilus-dependent motility	Any process involved in the controlled movement of a bacterial cell which is dependent on the presence of type IV pili. Includes social gliding motility and twitching motility.	tmpzr1t_l9r_go_relaxed.owl	twitching motility|type 4 pilus-dependent motility|social gliding motility|type four pilus-dependent motility|TFP-dependent movement|TFP-dependent motility													biological_process											owl:Class	
GO:0048870	biolink:NamedThing	cell motility	Any process involved in the controlled self-propelled movement of a cell that results in translocation of the cell from one place to another.	tmpzr1t_l9r_go_relaxed.owl	cell locomotion|movement of a cell|cell movement													biological_process											owl:Class	
GO:0071650	biolink:NamedThing	negative regulation of chemokine (C-C motif) ligand 5 production	Any process that stops, prevents, or reduces the frequency, rate, or extent of production of chemokine (C-C motif) ligand 5.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of RANTES production|negative regulation of Regulated upon Activation, Normal T-cell Expressed, and Secreted production|negative regulation of CCL5 production							mah	2010-02-12T10:40:19Z					biological_process											owl:Class	
GO:0071649	biolink:NamedThing	regulation of chemokine (C-C motif) ligand 5 production	Any process that modulates the frequency, rate, or extent of production of chemokine (C-C motif) ligand 5.	tmpzr1t_l9r_go_relaxed.owl	regulation of RANTES production|regulation of Regulated upon Activation, Normal T-cell Expressed, and Secreted production|regulation of CCL5 production							mah	2010-02-12T10:40:19Z					biological_process											owl:Class	
GO:2000106	biolink:NamedThing	regulation of leukocyte apoptotic process	Any process that modulates the frequency, rate or extent of leukocyte apoptotic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of leukocyte apoptosis							mah	2010-09-15T01:42:05Z					biological_process											owl:Class	
GO:2000356	biolink:NamedThing	regulation of kidney smooth muscle cell differentiation	Any process that modulates the frequency, rate or extent of kidney smooth muscle cell differentiation.	tmpzr1t_l9r_go_relaxed.owl								yaf	2011-02-03T02:14:24Z					biological_process											owl:Class	
GO:0051150	biolink:NamedThing	regulation of smooth muscle cell differentiation	Any process that modulates the frequency, rate or extent of smooth muscle cell differentiation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0099529	biolink:NamedThing	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential	Neurotransmitter receptor activity occurring in the postsynaptic membrane that is involved in regulating postsynaptic membrane potential, either directly (ionotropic receptors) or indirectly (e.g. via GPCR activation of an ion channel).	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1903459	biolink:NamedThing	mitotic DNA replication lagging strand elongation	Any lagging strand elongation that is involved in mitotic cell cycle DNA replication.	tmpzr1t_l9r_go_relaxed.owl	lagging strand elongation involved in DNA replication during S phase involved in mitotic cell cycle|lagging strand elongation involved in DNA replication involved in S phase involved in mitotic cell cycle|lagging strand elongation involved in mitotic nuclear cell cycle DNA replication|lagging strand elongation involved in DNA replication involved in S-phase involved in mitotic cell cycle|lagging strand elongation involved in mitotic DNA replication|lagging strand elongation involved in nuclear cell cycle DNA replication involved in mitotic cell cycle							vw	2014-09-23T13:32:54Z					biological_process											owl:Class	
GO:1902983	biolink:NamedThing	DNA strand elongation involved in mitotic DNA replication	Any DNA strand elongation involved in mitotic cell cycle DNA replication.	tmpzr1t_l9r_go_relaxed.owl	DNA strand elongation involved in mitotic cell cycle DNA replication							jl	2014-05-06T20:33:22Z					biological_process											owl:Class	
GO:0070821	biolink:NamedThing	tertiary granule membrane	The lipid bilayer surrounding a tertiary granule.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-07-20T03:59:41Z					cellular_component											owl:Class	
GO:0046368	biolink:NamedThing	GDP-L-fucose metabolic process	The chemical reactions and pathways involving GDP-L-fucose, a substance composed of L-fucose in glycosidic linkage with guanosine diphosphate.	tmpzr1t_l9r_go_relaxed.owl	GDP-L-fucose metabolism													biological_process											owl:Class	
GO:0072270	biolink:NamedThing	metanephric short nephron development	The process whose specific outcome is the progression of a short nephron in the metanephros over time, from its formation to the mature structure. Short nephrons are associated with mid-cortical and superficial glomeruli, are situated entirely in the outer medulla, and have no thin ascending limb.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-03-30T03:15:18Z					biological_process											owl:Class	
GO:0072210	biolink:NamedThing	metanephric nephron development	The process whose specific outcome is the progression of a nephron in the metanephros over time, from its formation to the mature structure. A nephron is the functional unit of the kidney.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-03-18T12:52:57Z					biological_process											owl:Class	
GO:0061328	biolink:NamedThing	posterior Malpighian tubule development	The process whose specific outcome is the progression of the posterior Malpighian tubule over time, from its formation to the mature structure. The pair of posterior tubules arise from a ventrolateral region of the embryonic hindgut and project backwards through the body cavity. A Malpighian tubule is a fine, thin-walled excretory tubule in insects which connects with the posterior part of the gut.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-09-28T01:24:35Z					biological_process											owl:Class	
GO:0072002	biolink:NamedThing	Malpighian tubule development	The process whose specific outcome is the progression of the Malpighian tubule over time, from its formation to the mature structure. A Malpighian tubule is a fine, thin-walled excretory tubule in insects which leads into the posterior part of the gut.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-01-25T10:54:30Z					biological_process											owl:Class	
GO:0090272	biolink:NamedThing	negative regulation of fibroblast growth factor production	Any process that decreases the rate, frequency or extent of the appearance of a fibroblast growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	tmpzr1t_l9r_go_relaxed.owl								tb	2010-02-05T02:33:33Z					biological_process											owl:Class	
GO:0010651	biolink:NamedThing	negative regulation of cell communication by electrical coupling	Any process that decreases the frequency, rate or extent of cell communication via electrical coupling. Cell communication via electrical coupling is the process that mediates signaling interactions between one cell and another cell by transfer of current between their adjacent cytoplasms via intercellular protein channels.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:2000934	biolink:NamedThing	negative regulation of cellotriose metabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of cellotriose metabolic process.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of cellotriose metabolism							tt	2011-08-01T12:44:20Z					biological_process											owl:Class	
GO:0002811	biolink:NamedThing	negative regulation of antifungal peptide biosynthetic process	Any process that stops, prevents, or reduces the frequency, rate, or extent of antifungal peptide biosynthesis.	tmpzr1t_l9r_go_relaxed.owl	inhibition of antifungal peptide biosynthetic process|down regulation of antifungal peptide biosynthetic process|downregulation of antifungal peptide biosynthetic process|down-regulation of antifungal peptide biosynthetic process													biological_process											owl:Class	
GO:0002789	biolink:NamedThing	negative regulation of antifungal peptide production	Any process that stops, prevents, or reduces the frequency, rate, or extent of antifungal peptide production.	tmpzr1t_l9r_go_relaxed.owl	down regulation of antifungal peptide production|inhibition of antifungal peptide production|down-regulation of antifungal peptide production|downregulation of antifungal peptide production													biological_process											owl:Class	
GO:0018898	biolink:NamedThing	2,4-dichlorobenzoate metabolic process	The chemical reactions and pathways involving 2,4-dichlorobenzoate, a chlorinated aromatic compound which is a key intermediate in the aerobic degradation of polychlorinated biphenyls (PCBs).	tmpzr1t_l9r_go_relaxed.owl	2,4-dichlorobenzoate metabolism				UM-BBD_pathwayID:dcb									biological_process											owl:Class	
GO:0035437	biolink:NamedThing	maintenance of protein localization in endoplasmic reticulum	Any process in which a protein is maintained in the endoplasmic reticulum and prevented from moving elsewhere. These include sequestration within the endoplasmic reticulum, protein stabilization to prevent transport elsewhere and the active retrieval of proteins that escape the endoplasmic reticulum.	tmpzr1t_l9r_go_relaxed.owl	maintenance of protein localization in ER|retention of protein in ER|maintenance of protein location in ER|maintenance of protein location in endoplasmic reticulum|retention of protein in endoplasmic reticulum|maintenance of protein localisation in endoplasmic reticulum|protein-endoplasmic reticulum retention|protein-ER retention							bf	2010-04-09T10:39:49Z					biological_process											owl:Class	
GO:0045185	biolink:NamedThing	maintenance of protein location	Any process in which a protein is maintained in a location and prevented from moving elsewhere. These include sequestration, stabilization to prevent transport elsewhere and the active retrieval of proteins that do move away.	tmpzr1t_l9r_go_relaxed.owl	active protein retrieval|protein sequestering|maintenance of protein localization|protein retention													biological_process											owl:Class	
GO:0072527	biolink:NamedThing	pyrimidine-containing compound metabolic process	The chemical reactions and pathways involving a pyrimidine-containing compound, i.e. any compound that contains pyrimidine or a formal derivative thereof.	tmpzr1t_l9r_go_relaxed.owl	pyrimidine and derivative metabolic process|pyrimidine-containing compound metabolism							mah	2011-01-04T03:27:19Z					biological_process											owl:Class	
GO:0071676	biolink:NamedThing	negative regulation of mononuclear cell migration	Any process that decreases the rate, frequency or extent of mononuclear cell migration. Mononuclear cell migration is the movement of a mononuclear cell within or between different tissues and organs of the body.	tmpzr1t_l9r_go_relaxed.owl	down regulation of mononuclear cell migration|down-regulation of mononuclear cell migration|downregulation of mononuclear cell migration|inhibition of mononuclear cell migration							mah	2010-02-16T02:13:55Z					biological_process											owl:Class	
GO:1902054	biolink:NamedThing	negative regulation of neosartoricin biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of neosartoricin biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of neosartoricin synthesis|negative regulation of neosartoricin anabolism|negative regulation of neosartoricin formation|down regulation of neosartoricin biosynthesis|down-regulation of neosartoricin formation|down regulation of neosartoricin anabolism|down-regulation of neosartoricin anabolism|inhibition of neosartoricin anabolism|inhibition of neosartoricin synthesis|downregulation of neosartoricin formation|down-regulation of neosartoricin biosynthetic process|downregulation of neosartoricin anabolism|negative regulation of neosartoricin synthesis|inhibition of neosartoricin biosynthetic process|negative regulation of neosartoricin biosynthesis|down regulation of neosartoricin synthesis|down-regulation of neosartoricin biosynthesis|down regulation of neosartoricin biosynthetic process|down regulation of neosartoricin formation|downregulation of neosartoricin biosynthetic process|downregulation of neosartoricin biosynthesis|inhibition of neosartoricin biosynthesis|inhibition of neosartoricin formation|downregulation of neosartoricin synthesis							di	2013-04-11T15:46:15Z					biological_process											owl:Class	
GO:1902053	biolink:NamedThing	regulation of neosartoricin biosynthetic process	Any process that modulates the frequency, rate or extent of neosartoricin biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of neosartoricin formation|regulation of neosartoricin anabolism|regulation of neosartoricin biosynthesis|regulation of neosartoricin synthesis							di	2013-04-11T15:46:06Z					biological_process											owl:Class	
GO:2001261	biolink:NamedThing	negative regulation of semaphorin-plexin signaling pathway	Any process that stops, prevents or reduces the frequency, rate or extent of semaphorin-plexin signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of semaphorin-plexin signalling pathway							vk	2011-12-08T02:05:48Z					biological_process											owl:Class	
GO:0009968	biolink:NamedThing	negative regulation of signal transduction	Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of signaling pathway|down-regulation of signal transduction|inhibition of signal transduction|down regulation of signal transduction|negative regulation of signalling pathway|downregulation of signal transduction											GO:0035467		biological_process											owl:Class	
GO:0030552	biolink:NamedThing	cAMP binding	Binding to cAMP, the nucleotide cyclic AMP (adenosine 3',5'-cyclophosphate).	tmpzr1t_l9r_go_relaxed.owl	3',5'-cAMP binding|adenosine 3',5'-cyclophosphate binding|cyclic AMP binding|3',5' cAMP binding													molecular_function											owl:Class	
GO:0030551	biolink:NamedThing	cyclic nucleotide binding	Binding to a cyclic nucleotide, a nucleotide in which the phosphate group is in diester linkage to two positions on the sugar residue.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0032434	biolink:NamedThing	regulation of proteasomal ubiquitin-dependent protein catabolic process	Any process that modulates the frequency, rate or extent of the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0061136	biolink:NamedThing	regulation of proteasomal protein catabolic process	Any process that modulates the rate, frequency, or extent of the chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds that is mediated by the proteasome.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-05-17T01:33:20Z					biological_process											owl:Class	
GO:0043371	biolink:NamedThing	negative regulation of CD4-positive, alpha-beta T cell differentiation	Any process that stops, prevents, or reduces the frequency, rate, or extent of CD4-positive, alpha-beta T cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of CD4-positive, alpha beta T cell differentiation|negative regulation of CD4-positive, alpha beta T-lymphocyte differentiation|negative regulation of CD4-positive, alpha beta T-cell differentiation|downregulation of CD4-positive, alpha beta T cell differentiation|inhibition of CD4-positive, alpha beta T cell differentiation|negative regulation of CD4-positive, alpha beta T cell development|negative regulation of CD4-positive T-cell differentiation|negative regulation of CD4-positive T-lymphocyte differentiation|down regulation of CD4-positive, alpha beta T cell differentiation|negative regulation of CD4-positive, alpha beta T lymphocyte differentiation					Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.								biological_process											owl:Class	
GO:0100009	biolink:NamedThing	regulation of fever generation by prostaglandin secretion	Any prostaglandin secretion process that regulates fever generation.	tmpzr1t_l9r_go_relaxed.owl								cjm	2015-04-02T04:13:19Z					biological_process											owl:Class	
GO:0071582	biolink:NamedThing	negative regulation of zinc ion transport	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of zinc ions (Zn2+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-01-28T03:14:25Z					biological_process											owl:Class	
GO:0044512	biolink:NamedThing	envenomation resulting in modulation of glucagon-like peptide receptor 1 activity in other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant modulation of glucagon-like peptide receptor 1 activity in of the bitten organism.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-02-26T10:20:19Z					biological_process											owl:Class	
GO:0044511	biolink:NamedThing	envenomation resulting in modulation of receptor activity in other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant modulation of receptor activity in of the bitten organism.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-02-26T10:12:24Z					biological_process											owl:Class	
GO:0035383	biolink:NamedThing	thioester metabolic process	The chemical reactions and pathways involving a thioester, a compound of general formula RC(=O)SR' in which the linking oxygen in an ester is replaced by a sulfur atom. They are the product of esterification between a carboxylic acid and a thiol.	tmpzr1t_l9r_go_relaxed.owl	thioester metabolism							bf	2010-03-18T01:48:12Z					biological_process											owl:Class	
GO:0060783	biolink:NamedThing	mesenchymal smoothened signaling pathway involved in prostate gland development	The series of molecular signals generated as a consequence of activation of the transmembrane Smoothened-type protein in the mesenchymal cells of the prostate that contribute to the progression of the prostate over time. This process contributes to lung development.	tmpzr1t_l9r_go_relaxed.owl	mesenchymal hedgehog signaling pathway involved in prostate gland development|mesenchymal hh signaling pathway involved in prostate gland development|mesenchymal smoothened signalling pathway involved in prostate gland development							dph	2009-07-28T11:57:59Z					biological_process											owl:Class	
GO:0007224	biolink:NamedThing	smoothened signaling pathway	A series of molecular signals generated as a consequence of activation of the transmembrane protein Smoothened.	tmpzr1t_l9r_go_relaxed.owl	Sonic hedgehog signaling pathway|hedgehog signaling pathway|hh signaling pathway|Shh signaling pathway|smoothened signalling pathway|hh signalling pathway				Wikipedia:Hedgehog_signaling_pathway									biological_process											owl:Class	
GO:0044272	biolink:NamedThing	sulfur compound biosynthetic process	The chemical reactions and pathways resulting in the formation of compounds that contain sulfur, such as the amino acids methionine and cysteine or the tripeptide glutathione.	tmpzr1t_l9r_go_relaxed.owl	sulfur compound formation|sulfur compound biosynthesis|sulfur biosynthesis|sulfur compound anabolism|sulfur biosynthetic process|sulfur compound synthesis													biological_process											owl:Class	
GO:0050575	biolink:NamedThing	2-(S)-hydroxypropyl-CoM dehydrogenase activity	Catalysis of the reaction: 2-(S)-hydroxypropyl-coenzyme M + NAD(+) = 2-oxopropyl-coenzyme M + H(+) + NADH.	tmpzr1t_l9r_go_relaxed.owl	2-(2-(S)-hydroxypropylthio)ethanesulfonate dehydrogenase activity|2-[2-(S)-hydroxypropylthio]ethanesulfonate:NAD+ oxidoreductase activity				MetaCyc:1.1.1.269-RXN|RHEA:21052|UM-BBD_reactionID:r0853|KEGG_REACTION:R05690|EC:1.1.1.269									molecular_function											owl:Class	
GO:0002132	biolink:NamedThing	wobble position uridine ribose methylation	The process in which the ribose of uridine at position 34 in the anticodon of a tRNA is post-transcriptionally methylated at the 2'-O position.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0002130	biolink:NamedThing	wobble position ribose methylation	The process in which the ribose base of the nucleotide at position 34 in the anticodon of a tRNA is post-transcriptionally methylated at the 2'O position.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0051268	biolink:NamedThing	alpha-keto amide reductase activity	Catalysis of the reaction: alpha-keto amide + 2 H+ (from donor) = (R)-hydroxy amide. Alpha-keto amides are of the form R-CO-CONH2, where R may be aromatic or aliphatic.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0016903	biolink:NamedThing	oxidoreductase activity, acting on the aldehyde or oxo group of donors	Catalysis of an oxidation-reduction (redox) reaction in which an aldehyde or ketone (oxo) group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.	tmpzr1t_l9r_go_relaxed.owl	oxidoreductase activity, acting on the aldehyde or oxo group of donors, other acceptors				EC:1.2.-.-									molecular_function											owl:Class	
GO:0033610	biolink:NamedThing	oxalate biosynthetic process	The chemical reactions and pathways resulting in the formation of oxalate, the organic acid ethanedioate.	tmpzr1t_l9r_go_relaxed.owl	oxalate anabolism|oxalate biosynthesis|oxalic acid biosynthetic process|ethanedioic acid biosynthetic process|ethanedioate biosynthetic process|oxalate formation|oxalate synthesis													biological_process											owl:Class	
GO:0033609	biolink:NamedThing	oxalate metabolic process	The chemical reactions and pathways involving oxalate, the organic acid ethanedioate.	tmpzr1t_l9r_go_relaxed.owl	oxalate metabolism|ethanedioate metabolic process|ethanedioic acid metabolic process|oxalic acid metabolic process													biological_process											owl:Class	
GO:0050336	biolink:NamedThing	thioethanolamine S-acetyltransferase activity	Catalysis of the reaction: acetyl-CoA + cysteamine = S-acetylcysteamine + CoA.	tmpzr1t_l9r_go_relaxed.owl	thioltransacetylase B activity|acetyl-CoA:thioethanolamine S-acetyltransferase activity|acetyl-CoA:2-aminoethanethiol S-acetyltransferase activity|thioethanolamine acetyltransferase activity				KEGG_REACTION:R03668|MetaCyc:THIOETHANOLAMINE-S-ACETYLTRANSFERASE-RXN|RHEA:23280|EC:2.3.1.11									molecular_function											owl:Class	
GO:0016418	biolink:NamedThing	S-acetyltransferase activity	Catalysis of the transfer of an acetyl group to a sulfur atom on the acceptor molecule.	tmpzr1t_l9r_go_relaxed.owl					EC:2.3.1.38									molecular_function											owl:Class	
GO:0098919	biolink:NamedThing	structural constituent of postsynaptic density	The action of a molecule that contributes to the structural integrity of a postsynaptic density.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0098879	biolink:NamedThing	structural constituent of postsynaptic specialization	The action of a molecule that contributes to the structural integrity of a postsynaptic specialization.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0106247	biolink:NamedThing	negative regulation of poly(A)-specific ribonuclease activity	Any process that stops, prevents or reduces the frequency, rate or extent of poly(A)-specific ribonuclease activity.	tmpzr1t_l9r_go_relaxed.owl								hjd	2020-02-03T19:01:02Z					biological_process											owl:Class	
GO:1903504	biolink:NamedThing	regulation of mitotic spindle checkpoint	Any process that modulates the frequency, rate or extent of mitotic spindle checkpoint.	tmpzr1t_l9r_go_relaxed.owl	regulation of mitotic cell cycle spindle checkpoint					Note that this term should not be used for direct manual annotation as it should always be possible to specify the type of spindle checkpoint (assembly, orientation or Dma1-dependent).		al	2014-10-01T13:52:57Z					biological_process											owl:Class	
GO:0018204	biolink:NamedThing	peptidyl-leucine modification	The modification of peptidyl-leucine.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0043990	biolink:NamedThing	histone H2A-S1 phosphorylation	The modification of histone H2A by the addition of an phosphate group to a serine residue at position 1 of the histone.	tmpzr1t_l9r_go_relaxed.owl	histone H2A phosphorylation at S1|histone H2AS1 phosphorylation													biological_process											owl:Class	
GO:0035404	biolink:NamedThing	histone-serine phosphorylation	The modification of histones by addition of a phosphate group to a serine residue.	tmpzr1t_l9r_go_relaxed.owl	histone serine phosphorylation							bf	2010-03-24T10:08:25Z					biological_process											owl:Class	
GO:0019872	biolink:NamedThing	streptomycin biosynthetic process	The chemical reactions and pathways resulting in the formation of streptomycin, a commonly used antibiotic in cell culture media; it acts only on prokaryotes and blocks transition from initiation complex to chain elongating ribosome.	tmpzr1t_l9r_go_relaxed.owl	streptomycin synthesis|streptomycin formation|streptomycin biosynthesis|streptomycin anabolism													biological_process											owl:Class	
GO:0046343	biolink:NamedThing	streptomycin metabolic process	The chemical reactions and pathways involving streptomycin, a commonly used antibiotic in cell culture media. It acts only on prokaryotes and blocks transition from initiation complex to chain elongating ribosome.	tmpzr1t_l9r_go_relaxed.owl	streptomycin metabolism													biological_process											owl:Class	
GO:0045144	biolink:NamedThing	meiotic sister chromatid segregation	The cell cycle process in which sister chromatids are organized and then physically separated and randomly apportioned to two sets during the second division of the meiotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl	meiosis II, chromosome segregation													biological_process											owl:Class	
GO:0000819	biolink:NamedThing	sister chromatid segregation	The cell cycle process in which sister chromatids are organized and then physically separated and apportioned to two or more sets.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1904988	biolink:NamedThing	negative regulation of endothelial cell activation	Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell activation.	tmpzr1t_l9r_go_relaxed.owl	down regulation of endothelial cell activation|downregulation of endothelial cell activation|inhibition of endothelial cell activation|down-regulation of endothelial cell activation							bc	2016-02-29T16:16:18Z					biological_process											owl:Class	
GO:0070067	biolink:NamedThing	syntaxin-6-syntaxin-16-Vti1a complex	A SNARE complex that contains syntaxin 6, syntaxin 16, and Vti1a (or orthologs thereof).	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0031201	biolink:NamedThing	SNARE complex	A protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers. One well-characterized example is the neuronal SNARE complex formed of synaptobrevin 2, syntaxin 1a, and SNAP-25.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:1901739	biolink:NamedThing	regulation of myoblast fusion	Any process that modulates the frequency, rate or extent of myoblast fusion.	tmpzr1t_l9r_go_relaxed.owl								rl	2013-01-11T20:23:50Z					biological_process											owl:Class	
GO:1904650	biolink:NamedThing	negative regulation of fat cell apoptotic process	Any process that stops, prevents or reduces the frequency, rate or extent of fat cell apoptotic process.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of fat cell apoptosis|down-regulation of fat cell apoptotic process|down-regulation of adipocyte apoptosis|down regulation of fat cell apoptosis|negative regulation of adipocyte apoptotic process|downregulation of adipose cell apoptotic process|downregulation of fat cell apoptotic process|down-regulation of adipocyte apoptotic process|inhibition of fat cell apoptosis|inhibition of adipose cell apoptotic process|down regulation of adipose cell apoptosis|negative regulation of adipocyte apoptosis|downregulation of adipose cell apoptosis|negative regulation of fat cell apoptosis|inhibition of adipocyte apoptosis|negative regulation of adipose cell apoptotic process|down regulation of adipose cell apoptotic process|down-regulation of adipose cell apoptosis|down-regulation of adipose cell apoptotic process|downregulation of adipocyte apoptosis|down regulation of adipocyte apoptosis|inhibition of fat cell apoptotic process|downregulation of fat cell apoptosis|down regulation of fat cell apoptotic process|downregulation of adipocyte apoptotic process|down regulation of adipocyte apoptotic process|negative regulation of adipose cell apoptosis|inhibition of adipocyte apoptotic process|inhibition of adipose cell apoptosis							sl	2015-08-31T20:59:34Z					biological_process											owl:Class	
GO:1904649	biolink:NamedThing	regulation of fat cell apoptotic process	Any process that modulates the frequency, rate or extent of fat cell apoptotic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of fat cell apoptosis|regulation of adipocyte apoptotic process|regulation of adipocyte apoptosis|regulation of adipose cell apoptotic process|regulation of adipose cell apoptosis							sl	2015-08-31T20:59:28Z					biological_process											owl:Class	
GO:2000372	biolink:NamedThing	negative regulation of DNA topoisomerase (ATP-hydrolyzing) activity	Any process that stops, prevents or reduces the frequency, rate or extent of DNA topoisomerase (ATP-hydrolyzing) activity.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of deoxyribonucleate topoisomerase|negative regulation of type II DNA topoisomerase activity|negative regulation of topoisomerase|negative regulation of DNA topoisomerase (ATP-hydrolysing)|negative regulation of topoisomerase II|negative regulation of deoxyribonucleic topoisomerase activity|negative regulation of DNA topoisomerase IV activity|negative regulation of DNA topoisomerase type II activity|negative regulation of DNA topoisomerase II							mah	2011-02-09T02:35:36Z					biological_process											owl:Class	
GO:0043086	biolink:NamedThing	negative regulation of catalytic activity	Any process that stops or reduces the activity of an enzyme.	tmpzr1t_l9r_go_relaxed.owl	downregulation of metalloenzyme activity|down regulation of metalloenzyme activity|inhibition of enzyme activity|negative regulation of metalloenzyme activity|down-regulation of metalloenzyme activity|negative regulation of enzyme activity|down regulation of enzyme activity|down-regulation of enzyme activity|downregulation of enzyme activity|inhibition of metalloenzyme activity											GO:0048553		biological_process											owl:Class	
GO:0010811	biolink:NamedThing	positive regulation of cell-substrate adhesion	Any process that increases the frequency, rate or extent of cell-substrate adhesion. Cell-substrate adhesion is the attachment of a cell to the underlying substrate via adhesion molecules.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0010810	biolink:NamedThing	regulation of cell-substrate adhesion	Any process that modulates the frequency, rate or extent of cell-substrate adhesion. Cell-substrate adhesion is the attachment of a cell to the underlying substrate via adhesion molecules.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0071171	biolink:NamedThing	site-specific DNA replication termination at RTS1 barrier	A DNA replication termination process that takes place at the RTS1 termination site in the mating type locus, in a specific direction required for subsequent imprinting and mating-type switching.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-11-20T01:24:41Z					biological_process											owl:Class	
GO:0071170	biolink:NamedThing	site-specific DNA replication termination	A DNA replication termination process that takes place at a specific termination site.	tmpzr1t_l9r_go_relaxed.owl						See also the biological process term 'replication fork arrest ; GO:0043111' and its children.		mah	2009-11-20T01:07:30Z					biological_process											owl:Class	
GO:0060226	biolink:NamedThing	negative regulation of retinal cone cell fate commitment	Any process that increases the process in which a cell becomes committed to a retinal cone cell fate. Retinal cone cell fate commitment is the process in which the developmental fate of a cell becomes restricted such that it will develop into a retinal cone cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1901467	biolink:NamedThing	negative regulation of ferulate catabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of ferulate catabolic process.	tmpzr1t_l9r_go_relaxed.owl	inhibition of ferulate catabolism|down regulation of ferulate catabolic process|down-regulation of ferulate catabolism|down regulation of ferulate breakdown|downregulation of ferulate catabolic process|down-regulation of ferulate catabolic process|down regulation of ferulate catabolism|downregulation of ferulate degradation|down regulation of ferulate degradation|inhibition of ferulate breakdown|downregulation of ferulate catabolism|down-regulation of ferulate breakdown|negative regulation of ferulate degradation|negative regulation of ferulate breakdown|down-regulation of ferulate degradation|downregulation of ferulate breakdown|negative regulation of ferulate catabolism|inhibition of ferulate degradation|inhibition of ferulate catabolic process							tt	2012-10-02T14:38:38Z					biological_process											owl:Class	
GO:1905339	biolink:NamedThing	positive regulation of cohesin unloading	Any process that activates or increases the frequency, rate or extent of cohesin unloading.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of cohesin unloading|upregulation of cohesin unloading|up regulation of cohesin unloading|activation of cohesin unloading							vw	2016-07-26T16:24:06Z					biological_process											owl:Class	
GO:0004139	biolink:NamedThing	deoxyribose-phosphate aldolase activity	Catalysis of the reaction: 2-deoxy-D-ribose 5-phosphate = D-glyceraldehyde 3-phosphate + acetaldehyde.	tmpzr1t_l9r_go_relaxed.owl	2-deoxy-D-ribose-5-phosphate acetaldehyde-lyase (D-glyceraldehyde-3-phosphate-forming)|deoxyriboaldolase activity|2-deoxy-D-ribose-5-phosphate acetaldehyde-lyase activity|phosphodeoxyriboaldolase activity|2-deoxyribose-5-phosphate aldolase activity|deoxyribose-5-phosphate aldolase activity				Reactome:R-HSA-6787321|EC:4.1.2.4|MetaCyc:DEOXYRIBOSE-P-ALD-RXN|KEGG_REACTION:R01066|RHEA:12821									molecular_function											owl:Class	
GO:0016832	biolink:NamedThing	aldehyde-lyase activity	Catalysis of the cleavage of a C-C bond in a molecule containing a hydroxyl group and a carbonyl group to form two smaller molecules, each being an aldehyde or a ketone.	tmpzr1t_l9r_go_relaxed.owl	aldolase activity				EC:4.1.2.-							GO:0016228		molecular_function											owl:Class	
GO:0046395	biolink:NamedThing	carboxylic acid catabolic process	The chemical reactions and pathways resulting in the breakdown of carboxylic acids, any organic acid containing one or more carboxyl (-COOH) groups.	tmpzr1t_l9r_go_relaxed.owl	carboxylic acid degradation|carboxylic acid catabolism|carboxylic acid breakdown													biological_process											owl:Class	
GO:0048561	biolink:NamedThing	establishment of animal organ orientation	The process that determines the orientation of an animal organ or tissue with reference to an axis.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0035892	biolink:NamedThing	modulation of platelet aggregation in other organism	Any process in which an organism modulates the frequency, rate or extent of platelet aggregation in another organism. Platelet aggregation is the adhesion of one platelet to one or more other platelets via adhesion molecules.	tmpzr1t_l9r_go_relaxed.owl	regulation of platelet aggregation in other organism|modulation by organism of platelet aggregation in other organism							bf	2011-06-15T02:21:10Z					biological_process											owl:Class	
GO:0044364	biolink:NamedThing	disruption of cells of other organism	A process in which an organism has a negative effect on the functioning of the second organism's cells.	tmpzr1t_l9r_go_relaxed.owl								jl	2011-10-27T02:27:48Z					biological_process											owl:Class	
GO:2000794	biolink:NamedThing	regulation of epithelial cell proliferation involved in lung morphogenesis	Any process that modulates the frequency, rate or extent of epithelial cell proliferation involved in lung morphogenesis.	tmpzr1t_l9r_go_relaxed.owl								pr	2011-06-25T07:22:38Z					biological_process											owl:Class	
GO:0042834	biolink:NamedThing	peptidoglycan binding	Interacting selectively and non-covalently, in a non-covalent manner, with peptidoglycan, any of a class of glycoconjugates found in bacterial cell walls.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0005539	biolink:NamedThing	glycosaminoglycan binding	Binding to a glycan (polysaccharide) containing a substantial proportion of aminomonosaccharide residues.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0060264	biolink:NamedThing	regulation of respiratory burst involved in inflammatory response	Any process that modulates the rate, frequency or extent of a phase of elevated metabolic activity, during which oxygen consumption increases made as a defense response ; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals.	tmpzr1t_l9r_go_relaxed.owl	regulation of respiratory burst involved in acute inflammatory response													biological_process											owl:Class	
GO:1902129	biolink:NamedThing	(-)-lariciresinol biosynthetic process	The chemical reactions and pathways resulting in the formation of (-)-lariciresinol.	tmpzr1t_l9r_go_relaxed.owl	(-)-lariciresinol synthesis|(-)-lariciresinol formation|(-)-lariciresinol anabolism|(-)-lariciresinol biosynthesis							ms	2013-05-21T08:49:44Z					biological_process											owl:Class	
GO:0009807	biolink:NamedThing	lignan biosynthetic process	The chemical reactions and pathways resulting in the formation of lignans, any member of a class of plant metabolites related to lignins. Lignans are usually found as phenylpropanoid dimers in which the phenylpropanoid units are linked tail to tail and thus having a 2,3 dibenzylbutane skeleton, but higher oligomers can also exist.	tmpzr1t_l9r_go_relaxed.owl	lignan biosynthesis|lignan anabolism|lignan formation|lignan synthesis													biological_process											owl:Class	
GO:1903069	biolink:NamedThing	regulation of ER-associated ubiquitin-dependent protein catabolic process	Any process that modulates the frequency, rate or extent of ER-associated ubiquitin-dependent protein catabolic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of ER-associated protein degradation|regulation of ERAD|regulation of endoplasmic reticulum-associated protein catabolism|regulation of ER-associated protein breakdown|regulation of ER-associated protein catabolic process|regulation of endoplasmic reticulum-associated protein catabolic process|regulation of ER-associated protein catabolism							rph	2014-05-28T17:53:46Z					biological_process											owl:Class	
GO:1903023	biolink:NamedThing	regulation of ascospore-type prospore membrane formation	Any process that modulates the frequency, rate or extent of formation of an ascospore-type prospore membrane.	tmpzr1t_l9r_go_relaxed.owl	regulation of FSM biosynthesis|regulation of forespore membrane biosynthesis|regulation of FSM formation|regulation of FSM assembly|regulation of ascospore-type prospore membrane assembly|regulation of forespore membrane formation							al	2014-05-15T08:51:51Z					biological_process											owl:Class	
GO:0044087	biolink:NamedThing	regulation of cellular component biogenesis	Any process that modulates the frequency, rate or extent of cellular component biogenesis, a process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cellular component.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0060704	biolink:NamedThing	acinar cell differentiation involved in salivary gland development	The process in which a relatively unspecialized cell acquires specialized structural and/or functional features that characterize an acinar cell of the salivary gland. Acinar cells are protein-secreting cells in the gland.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-06-09T09:32:46Z					biological_process											owl:Class	
GO:0060690	biolink:NamedThing	epithelial cell differentiation involved in salivary gland development	The process in which a relatively unspecialized cell acquire specialized structural and/or functional features of an epithelial cell of the salivary gland.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-06-08T01:04:19Z					biological_process											owl:Class	
GO:0070986	biolink:NamedThing	left/right axis specification	The establishment, maintenance and elaboration of the left/right axis. The left/right axis is defined by a line that runs orthogonal to both the anterior/posterior and dorsal/ventral axes. Each side is defined from the viewpoint of the organism rather of the observer (as per anatomical axes).	tmpzr1t_l9r_go_relaxed.owl	left/right axis determination|left-right axis specification							mah	2009-10-29T01:43:34Z					biological_process											owl:Class	
GO:0009798	biolink:NamedThing	axis specification	The establishment, maintenance and elaboration of a pattern along a line or around a point.	tmpzr1t_l9r_go_relaxed.owl	axis determination													biological_process											owl:Class	
GO:0030980	biolink:NamedThing	alpha-glucan catabolic process	The chemical reactions and pathways resulting in the breakdown of alpha-glucans.	tmpzr1t_l9r_go_relaxed.owl	alpha-glucan degradation|alpha-glucan catabolism|alpha-glucan breakdown													biological_process											owl:Class	
GO:0009251	biolink:NamedThing	glucan catabolic process	The chemical reactions and pathways resulting in the breakdown of glucans, polysaccharides consisting only of glucose residues.	tmpzr1t_l9r_go_relaxed.owl	glucan catabolism|glucan degradation|glucan breakdown													biological_process											owl:Class	
GO:2001009	biolink:NamedThing	regulation of plant-type cell wall cellulose biosynthetic process	Any process that modulates the frequency, rate or extent of plant-type cell wall cellulose biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of cell wall cellulose biosynthesis|regulation of cellulose biosynthesis during cell wall biosynthesis							tt	2011-08-08T08:47:15Z					biological_process											owl:Class	
GO:0050867	biolink:NamedThing	positive regulation of cell activation	Any process that activates or increases the frequency, rate or extent of activation.	tmpzr1t_l9r_go_relaxed.owl	up regulation of cell activation|up-regulation of cell activation|activation of cell activation|upregulation of cell activation|stimulation of cell activation													biological_process											owl:Class	
GO:0044011	biolink:NamedThing	single-species biofilm formation on inanimate substrate	A process in which microorganisms of the same species attach to and grow on an inanimate surface such as a rock or pipe, and produce extracellular polymers that facilitate attachment and matrix formation, resulting in an alteration in the phenotype of the organisms with respect to growth rate and gene transcription.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0090609	biolink:NamedThing	single-species submerged biofilm formation	A process in which planktonically growing microorganisms of the same species aggregate and grow on solid substrates under the flow of a liquid and produce extracellular polymers that facilitate attachment and matrix formation, resulting in a change in the organisms' growth rate and gene transcription.	tmpzr1t_l9r_go_relaxed.owl								tb	2014-09-16T14:55:15Z					biological_process											owl:Class	
GO:0061273	biolink:NamedThing	mesonephric distal tubule morphogenesis	The process in which the anatomical structures of a mesonephric distal tubule are generated and organized. The mesonephric distal tubule is a mesonephric nephron tubule that begins at the macula densa and extends to the mesonephric connecting tubule.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-09-02T12:12:00Z					biological_process											owl:Class	
GO:0061240	biolink:NamedThing	mesonephric nephron tubule morphogenesis	The process in which the anatomical structures of a mesonephric nephron tubule are generated and organized. A mesonephric nephron tubule is an epithelial tube that is part of the mesonephric nephron, the functional part of the mesonephros.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-08-19T03:09:26Z					biological_process											owl:Class	
GO:0033653	biolink:NamedThing	host cell chloroplast part	Any constituent part of a chloroplast as it is found in host cells and which are a chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	host chloroplast component					Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.								cellular_component											owl:Class	
GO:0033652	biolink:NamedThing	host cell chloroplast	A chlorophyll-containing plastid as found within host cells with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0002188	biolink:NamedThing	translation reinitiation	A gene-specific translational control mechanism where the small ribosomal subunit remains attached to the mRNA following termination of translation, then resumes scanning on the same mRNA molecule and initiates again at a downstream start site. Reinitiation depends on de novo recruitment of the ternary complex that is required to recognize the next AUG codon.	tmpzr1t_l9r_go_relaxed.owl								hjd	2011-06-22T12:31:13Z					biological_process											owl:Class	
GO:0002183	biolink:NamedThing	cytoplasmic translational initiation	The process preceding formation of the peptide bond between the first two amino acids of a protein in the cytoplasm. This includes the formation of a complex of the ribosome, mRNA or circRNA, and an initiation complex that contains the first aminoacyl-tRNA.	tmpzr1t_l9r_go_relaxed.owl								hjd	2011-06-09T03:15:48Z					biological_process											owl:Class	
GO:1905044	biolink:NamedThing	regulation of Schwann cell proliferation involved in axon regeneration	Any process that modulates the frequency, rate or extent of Schwann cell proliferation involved in axon regeneration.	tmpzr1t_l9r_go_relaxed.owl								rph	2016-03-11T14:47:35Z					biological_process											owl:Class	
GO:0010624	biolink:NamedThing	regulation of Schwann cell proliferation	Any process that modulates the frequency or rate of multiplication or reproduction of Schwann cells, resulting in the expansion of their population. Schwann cells are a type of glial cell in the peripheral nervous system.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0046311	biolink:NamedThing	prenylcysteine biosynthetic process	The chemical reactions and pathways resulting in the formation of prenylcysteine, 3-methyl-2-buten-1-yl-cysteine, a derivative of the amino acid cysteine formed by the covalent addition of a prenyl residue.	tmpzr1t_l9r_go_relaxed.owl	prenylcysteine biosynthesis|prenylcysteine anabolism|prenylcysteine synthesis|prenylcysteine formation													biological_process											owl:Class	
GO:0030329	biolink:NamedThing	prenylcysteine metabolic process	The chemical reactions and pathways involving prenylcysteine, 3-methyl-2-buten-1-yl-cysteine, a derivative of the amino acid cysteine formed by the covalent addition of a prenyl residue.	tmpzr1t_l9r_go_relaxed.owl	prenylcysteine metabolism													biological_process											owl:Class	
GO:0106096	biolink:NamedThing	response to ceramide	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ceramide stimulus.	tmpzr1t_l9r_go_relaxed.owl								hjd	2018-02-12T19:48:43Z					biological_process											owl:Class	
GO:0060138	biolink:NamedThing	fetal process involved in parturition	A reproductive process occurring in the embryo that results in birth.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0048609	biolink:NamedThing	multicellular organismal reproductive process	The process, occurring above the cellular level, that is pertinent to the reproductive function of a multicellular organism. This includes the integrated processes at the level of tissues and organs.	tmpzr1t_l9r_go_relaxed.owl	organismal reproductive process|reproductive process in a multicellular organism													biological_process											owl:Class	
GO:0009395	biolink:NamedThing	phospholipid catabolic process	The chemical reactions and pathways resulting in the breakdown of phospholipids, any lipid containing phosphoric acid as a mono- or diester.	tmpzr1t_l9r_go_relaxed.owl	phospholipid breakdown|phospholipid degradation|phospholipid catabolism													biological_process											owl:Class	
GO:0046434	biolink:NamedThing	organophosphate catabolic process	The chemical reactions and pathways resulting in the breakdown of organophosphates, any phosphate-containing organic compound.	tmpzr1t_l9r_go_relaxed.owl	organophosphate catabolism|organophosphate breakdown|organophosphate degradation													biological_process											owl:Class	
GO:1900940	biolink:NamedThing	positive regulation of (Z)-nonadeca-1,14-diene metabolic process	Any process that activates or increases the frequency, rate or extent of (Z)-nonadeca-1,14-diene metabolic process.	tmpzr1t_l9r_go_relaxed.owl	up regulation of (Z)-nonadeca-1,14-diene metabolic process|up regulation of (Z)-nonadeca-1,14-diene metabolism|up-regulation of (Z)-nonadeca-1,14-diene metabolism|activation of (Z)-nonadeca-1,14-diene metabolism|activation of (Z)-nonadeca-1,14-diene metabolic process|up-regulation of (Z)-nonadeca-1,14-diene metabolic process|upregulation of (Z)-nonadeca-1,14-diene metabolism|upregulation of (Z)-nonadeca-1,14-diene metabolic process|positive regulation of (Z)-nonadeca-1,14-diene metabolism							tt	2012-06-14T03:16:05Z					biological_process											owl:Class	
GO:1900910	biolink:NamedThing	positive regulation of olefin metabolic process	Any process that activates or increases the frequency, rate or extent of olefin metabolic process.	tmpzr1t_l9r_go_relaxed.owl	up regulation of olefin metabolic process|upregulation of olefin metabolic process|activation of olefin metabolic process|positive regulation of olefin metabolism|up-regulation of olefin metabolism|upregulation of olefin metabolism|up-regulation of olefin metabolic process|activation of olefin metabolism|up regulation of olefin metabolism							tt	2012-06-13T04:18:58Z					biological_process											owl:Class	
GO:0102405	biolink:NamedThing	(+)-taxifolin 5'-hydroxylase activity	Catalysis of the reaction: (+)-taxifolin(1-) + O2 + NADPH(4-) + H+ <=> (+)-dihydromyricetin + NADP(3-) + H2O.	tmpzr1t_l9r_go_relaxed.owl					RHEA:61116|MetaCyc:RXN-13718									molecular_function											owl:Class	
GO:0002557	biolink:NamedThing	histamine secretion by basophil	The regulated release of histamine by a basophil or group of basophils.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0002441	biolink:NamedThing	histamine secretion involved in inflammatory response	The regulated release of histamine by a cell as part of an inflammatory response.	tmpzr1t_l9r_go_relaxed.owl	histamine secretion involved in acute inflammatory response													biological_process											owl:Class	
GO:0019524	biolink:NamedThing	keto-D-gluconate catabolic process	The chemical reactions and pathways resulting in the breakdown of keto-D-gluconate, the anion of keto-D-gluconic acid, an aldonic acid derived from glucose.	tmpzr1t_l9r_go_relaxed.owl	keto-D-gluconate breakdown|keto-D-gluconate degradation|keto-D-gluconate catabolism				MetaCyc:DHGLUCONATE-PYR-CAT-PWY									biological_process											owl:Class	
GO:0046181	biolink:NamedThing	ketogluconate catabolic process	The chemical reactions and pathways resulting in the breakdown of ketogluconate, the anion of ketogluconic acid, an aldonic acid derived from glucose containing a ketonic carbonyl group.	tmpzr1t_l9r_go_relaxed.owl	ketogluconate degradation|ketogluconate breakdown|ketogluconate catabolism													biological_process											owl:Class	
GO:0047493	biolink:NamedThing	ceramide cholinephosphotransferase activity	Catalysis of the reaction: CDP-choline + ceramide = CMP + H(+) + sphingomyelin.	tmpzr1t_l9r_go_relaxed.owl	CDP-choline:N-acylsphingosine cholinephosphotransferase activity|phosphorylcholine-ceramide transferase activity				RHEA:16273|KEGG_REACTION:R01891|EC:2.7.8.3|MetaCyc:CERAMIDE-CHOLINEPHOSPHOTRANSFERASE-RXN									molecular_function											owl:Class	
GO:0072154	biolink:NamedThing	proximal convoluted tubule segment 1 cell fate commitment	The process in which the developmental fate of a cell becomes restricted such that it will develop into an S1 cell in the kidney.	tmpzr1t_l9r_go_relaxed.owl	S1 cell fate commitment							mah	2010-02-24T02:18:19Z					biological_process											owl:Class	
GO:0062146	biolink:NamedThing	4-chloro-allylglycine synthase activity	Catalysis of the reaction: 4-chloro-L-lysine + AH2 + O2 = A + formaldehyde + H2O + L-2-amino-4-chloropent-4-enoate + NH4(+).	tmpzr1t_l9r_go_relaxed.owl					RHEA:59888			dph	2019-09-02T16:59:30Z					molecular_function											owl:Class	
GO:0005587	biolink:NamedThing	collagen type IV trimer	A collagen heterotrimer containing type IV alpha chains; [alpha1(IV)]2alpha2(IV) trimers are commonly observed, although more type IV alpha chains exist and may be present in type IV trimers; type IV collagen triple helices associate to form 3 dimensional nets within basement membranes.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Collagen_type_IV									cellular_component											owl:Class	
GO:0098642	biolink:NamedThing	network-forming collagen trimer	A collagen trimer that forms networks.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0033233	biolink:NamedThing	regulation of protein sumoylation	Any process that modulates the frequency, rate or extent of the addition of SUMO groups to a protein.	tmpzr1t_l9r_go_relaxed.owl	regulation of sumoylation													biological_process											owl:Class	
GO:1904769	biolink:NamedThing	isopentadecanoic acid binding	Binding to isopentadecanoic acid.	tmpzr1t_l9r_go_relaxed.owl	13-methylmyristic acid binding							kmv	2015-10-27T21:33:38Z					molecular_function											owl:Class	
GO:0036041	biolink:NamedThing	long-chain fatty acid binding	Binding to a long-chain fatty acid. A long-chain fatty acid is a fatty acid with a chain length between C13 and C22.	tmpzr1t_l9r_go_relaxed.owl	long chain fatty acid binding							bf	2011-11-24T02:54:39Z					molecular_function											owl:Class	
GO:0008022	biolink:NamedThing	protein C-terminus binding	Binding to a protein C-terminus, the end of a peptide chain at which the 1-carboxyl function of a constituent amino acid is not attached in peptide linkage to another amino-acid residue.	tmpzr1t_l9r_go_relaxed.owl	COOH-terminus binding|carboxylate-terminus binding|carboxyl-terminus binding|carboxy-terminal binding|carboxylate-terminal binding|carboxy-terminus binding|COOH-terminal binding|C-terminal end binding|C-terminal binding|carboxyl-terminal binding													molecular_function											owl:Class	
GO:1905101	biolink:NamedThing	negative regulation of apoptosome assembly	Any process that stops, prevents or reduces the frequency, rate or extent of apoptosome assembly.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of apoptosome formation|down-regulation of apoptosome assembly|downregulation of apoptosome formation|down regulation of apoptosome formation|inhibition of apoptosome assembly|down regulation of apoptosome assembly|downregulation of apoptosome assembly|inhibition of apoptosome formation|down-regulation of apoptosome formation							bc	2016-04-04T08:57:51Z					biological_process											owl:Class	
GO:0003331	biolink:NamedThing	positive regulation of extracellular matrix constituent secretion	Any process that increases the rate, frequency, or extent of the controlled release of molecules that form the extracellular matrix, including carbohydrates and glycoproteins by a cell or a group of cells.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-11-02T02:11:22Z					biological_process											owl:Class	
GO:0017001	biolink:NamedThing	antibiotic catabolic process	The chemical reactions and pathways resulting in the breakdown of antibiotic, a substance produced by or derived from certain fungi, bacteria, and other organisms, that can destroy or inhibit the growth of other microorganisms.	tmpzr1t_l9r_go_relaxed.owl	antibiotic degradation|antibiotic breakdown|antibiotic catabolism													biological_process											owl:Class	
GO:0015960	biolink:NamedThing	diadenosine polyphosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of diadenosine polyphosphate, a derivative of the nucleoside adenosine with phosphate groups attached.	tmpzr1t_l9r_go_relaxed.owl	diadenosine polyphosphate anabolism|diadenosine polyphosphate formation|diadenosine polyphosphate biosynthesis|diadenosine polyphosphate synthesis													biological_process											owl:Class	
GO:0009165	biolink:NamedThing	nucleotide biosynthetic process	The chemical reactions and pathways resulting in the formation of nucleotides, any nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the glycose moiety; may be mono-, di- or triphosphate; this definition includes cyclic-nucleotides (nucleoside cyclic phosphates).	tmpzr1t_l9r_go_relaxed.owl	nucleotide anabolism|nucleotide formation|nucleotide biosynthesis|nucleotide synthesis													biological_process											owl:Class	
GO:0008061	biolink:NamedThing	chitin binding	Binding to chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0042863	biolink:NamedThing	pyochelin metabolic process	The chemical reactions and pathways involving the siderochrome pyochelin (2-(2-o-hydroxyphenyl-2-thiazolin-4-yl)-3-methylthiazolidine-4-carboxylic acid).	tmpzr1t_l9r_go_relaxed.owl	pyochelin metabolism													biological_process											owl:Class	
GO:0046927	biolink:NamedThing	peptidyl-threonine racemization	The racemization of peptidyl-L-threo-threonine at the alpha-carbon to form D-allo-threonine. This is coupled with the formation of the cross-link 2-(S-L-cysteinyl)-D-allo-threonine.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0018210	biolink:NamedThing	peptidyl-threonine modification	The modification of peptidyl-threonine.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0100001	biolink:NamedThing	regulation of skeletal muscle contraction by action potential	Any action potential process that regulates skeletal muscle contraction.	tmpzr1t_l9r_go_relaxed.owl								cjm	2015-04-02T04:13:19Z					biological_process											owl:Class	
GO:0001508	biolink:NamedThing	action potential	A process in which membrane potential cycles through a depolarizing spike, triggered in response to depolarization above some threshold, followed by repolarization. This cycle is driven by the flow of ions through various voltage gated channels with different thresholds and ion specificities.	tmpzr1t_l9r_go_relaxed.owl						Action potentials typically propagate across excitable membranes. This class covers both action potentials that propagate and those that fail to do so.								biological_process											owl:Class	
GO:1902333	biolink:NamedThing	nuclear DNA replication DNA ligation	Any DNA ligation that is involved in nuclear cell cycle DNA replication.	tmpzr1t_l9r_go_relaxed.owl	DNA ligation involved in DNA replication involved in S-phase|DNA ligation involved in nuclear cell cycle DNA replication|DNA ligation involved in DNA replication during S phase|DNA ligation involved in DNA replication involved in S phase							jl	2013-07-25T10:55:56Z					biological_process											owl:Class	
GO:0006266	biolink:NamedThing	DNA ligation	The re-formation of a broken phosphodiester bond in the DNA backbone, carried out by DNA ligase.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0036345	biolink:NamedThing	platelet maturation	A developmental process, independent of morphogenetic (shape) change, that is required for a platelet to attain its fully functional state. A platelet is a non-nucleated disk-shaped cell formed by extrusion from megakaryocytes, found in the blood of all mammals, and mainly involved in blood coagulation.	tmpzr1t_l9r_go_relaxed.owl								bf	2012-09-11T15:23:11Z					biological_process											owl:Class	
GO:0048469	biolink:NamedThing	cell maturation	A developmental process, independent of morphogenetic (shape) change, that is required for a cell to attain its fully functional state.	tmpzr1t_l9r_go_relaxed.owl	functional differentiation													biological_process											owl:Class	
GO:0051521	biolink:NamedThing	termination of monopolar cell growth	Any process that stops the active process of bipolar cell growth, polarized growth from one end of a cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0051514	biolink:NamedThing	negative regulation of monopolar cell growth	Any process that stops, prevents, or reduces the frequency, rate or extent of monopolar cell growth, polarized growth from one end of a cell.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of monopolar cell growth|down regulation of monopolar cell growth|inhibition of monopolar cell growth|downregulation of monopolar cell growth													biological_process											owl:Class	
GO:0036272	biolink:NamedThing	response to gemcitabine	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gemcitabine stimulus. Gemcitabine is a 2'-deoxycytidine having geminal fluoro substituents in the 2'-position, and is used as a drug in the treatment of various carcinomas.	tmpzr1t_l9r_go_relaxed.owl	response to 2',2'-difluorodeoxycytidine|response to 2'-deoxy-2',2'-difluorocytidine					Note that this term is in the subset of terms that should not be used for direct manual annotation of gene products. It was created to be used for cross-referencing by other ontologies. Direct annotations to this term may be amended during annotation QC.		bf	2012-07-09T01:36:03Z					biological_process											owl:Class	
GO:0120162	biolink:NamedThing	positive regulation of cold-induced thermogenesis	Any process that activates or increases the frequency, rate or extent of cold-induced thermogenesis.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of CIT							krc	2018-05-14T17:14:51Z					biological_process											owl:Class	
GO:0018517	biolink:NamedThing	phthalate 4,5-cis-dihydrodiol dehydrogenase activity	Catalysis of the reaction: cis-4,5-dihydroxycyclohexa-2,6-diene-1,2-dicarboxylate + NAD(+) = 4,5-dihydroxyphthalate + H(+) + NADH.	tmpzr1t_l9r_go_relaxed.owl	cis-4,5-dihydroxycyclohexa-1(6),2-diene-1,2-dicarboxylate:NAD+ oxidoreductase activity				RHEA:13837|EC:1.3.1.64|KEGG_REACTION:R05275|UM-BBD_reactionID:r0142|MetaCyc:1.3.1.64-RXN									molecular_function											owl:Class	
GO:0051999	biolink:NamedThing	mannosyl-inositol phosphorylceramide biosynthetic process	The chemical reactions and pathways resulting in the formation of mannosyl-inositol phosphorylceramide, any lipid with a phosphodiester bridge between an inositol residue and the ceramide group which contains a phosphoryl (-P(O)=) groups and a mannose derivative.	tmpzr1t_l9r_go_relaxed.owl	mannosyl-inositol phosphorylceramide synthesis|mannosyl-inositol phosphorylceramide anabolism|mannose-inositol-P-ceramide (MIPC) biosynthetic process|MIPC biosynthetic process|mannose inositol phosphoceramide biosynthetic process|mannosyl-inositol phosphorylceramide biosynthesis|mannosyl-inositol phosphorylceramide formation							ai	2010-07-20T10:16:26Z					biological_process											owl:Class	
GO:0006675	biolink:NamedThing	mannosyl-inositol phosphorylceramide metabolic process	The chemical reactions and pathways involving mannosyl-inositol phosphorylceramide, any lipid with a phosphodiester bridge between an inositol residue and the ceramide group which contains a phosphoryl (-P(O)=) groups and a mannose derivative.	tmpzr1t_l9r_go_relaxed.owl	MIPC metabolism|mannose-inositol-P-ceramide (MIPC) metabolism|mannose inositol phosphoceramide metabolism|mannose inositol phosphoceramide metabolic process|mannosyl-inositol-phosphorylceramide metabolism|mannose-inositol-P-ceramide (MIPC) metabolic process|MIPC metabolic process													biological_process											owl:Class	
GO:0034880	biolink:NamedThing	citrazinate dehydrogenase activity	Catalysis of the reaction: citrazinate + H2O = 2,3,6-trihydroxyisonicotinate + 2 H+ + 2 e-.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r1339									molecular_function											owl:Class	
GO:0016721	biolink:NamedThing	oxidoreductase activity, acting on superoxide radicals as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which a superoxide radical (O2- or O2.-) acts as a hydrogen or electron acceptor.	tmpzr1t_l9r_go_relaxed.owl					EC:1.15.-.-									molecular_function											owl:Class	
GO:0044547	biolink:NamedThing	DNA topoisomerase binding	Binding to a DNA topoisomerase.	tmpzr1t_l9r_go_relaxed.owl	DNA topoisomerase I binding							jl	2012-03-22T02:30:37Z			GO:0017033		molecular_function											owl:Class	
GO:0019899	biolink:NamedThing	enzyme binding	Binding to an enzyme, a protein with catalytic activity.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0042209	biolink:NamedThing	orcinol catabolic process	The chemical reactions and pathways resulting in the breakdown of orcinol (5-methyl-1,3-benzenediol), an aromatic compound derived from the fermentation of lichen and synthesized by some higher plants.	tmpzr1t_l9r_go_relaxed.owl	orcinol catabolism|orcinol breakdown|orcin catabolism|orcin catabolic process|orcinol degradation				UM-BBD_pathwayID:orc									biological_process											owl:Class	
GO:0018940	biolink:NamedThing	orcinol metabolic process	The chemical reactions and pathways involving orcinol (5-methyl-1,3-benzenediol), an aromatic compound derived from the fermentation of lichen, and synthesized, probably as a fungicide, by some higher plants.	tmpzr1t_l9r_go_relaxed.owl	orcinol metabolism|orcin metabolic process|orcin metabolism				MetaCyc:P342-PWY|UM-BBD_pathwayID:orc									biological_process											owl:Class	
GO:0106072	biolink:NamedThing	negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway	Any process that stops, prevents or reduces the frequency, rate or extent of an adenylate cyclase-activating G protein-coupled receptor signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of adenylate cyclase-activating G-protein coupled receptor signaling pathway							hjd	2017-11-28T18:41:31Z					biological_process											owl:Class	
GO:0008593	biolink:NamedThing	regulation of Notch signaling pathway	Any process that modulates the frequency, rate or extent of the Notch signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	regulation of N signalling pathway|regulation of N signaling pathway|regulation of Notch signalling pathway													biological_process											owl:Class	
GO:0001768	biolink:NamedThing	establishment of T cell polarity	The directed orientation of T cell signaling molecules and associated membrane rafts towards a chemokine gradient or a contact point with antigen presenting cell.	tmpzr1t_l9r_go_relaxed.owl	T cell polarization|establishment of T lymphocyte polarity|establishment of T-lymphocyte polarity|establishment of T-cell polarity|T-cell polarization|T lymphocyte polarization													biological_process											owl:Class	
GO:0001767	biolink:NamedThing	establishment of lymphocyte polarity	The directed orientation of lymphocyte signaling molecules and associated membrane rafts towards a chemokine gradient or a contact point with an appropriate activating cell.	tmpzr1t_l9r_go_relaxed.owl	lymphocyte polarization													biological_process											owl:Class	
GO:1901188	biolink:NamedThing	negative regulation of ephrin receptor signaling pathway	Any process that stops, prevents or reduces the frequency, rate or extent of ephrin receptor signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	inhibition of ephrin receptor signaling pathway|down-regulation of ephrin receptor signaling pathway|down regulation of ephrin receptor signaling pathway|inhibition of Eph receptor signaling pathway|down regulation of Eph receptor signaling pathway|downregulation of Eph receptor signaling pathway|negative regulation of Eph receptor signalling pathway|negative regulation of Eph receptor signaling pathway|down regulation of Eph receptor signalling pathway|down-regulation of Eph receptor signaling pathway|downregulation of ephrin receptor signaling pathway|downregulation of Eph receptor signalling pathway|down-regulation of Eph receptor signalling pathway|inhibition of Eph receptor signalling pathway							rl	2012-07-24T07:42:14Z					biological_process											owl:Class	
GO:1901187	biolink:NamedThing	regulation of ephrin receptor signaling pathway	Any process that modulates the frequency, rate or extent of ephrin receptor signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	regulation of Eph receptor signaling pathway|regulation of Eph receptor signalling pathway							rl	2012-07-24T07:41:49Z					biological_process											owl:Class	
GO:0016782	biolink:NamedThing	transferase activity, transferring sulphur-containing groups	Catalysis of the transfer of a sulfur-containing group from one compound (donor) to another (acceptor).	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/20486			EC:2.8.-.-									molecular_function											owl:Class	
GO:0090179	biolink:NamedThing	planar cell polarity pathway involved in neural tube closure	The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors that modulates the establishment of planar polarity contributing to neural tube closure.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-12-14T11:20:27Z					biological_process											owl:Class	
GO:0060071	biolink:NamedThing	Wnt signaling pathway, planar cell polarity pathway	The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors including C-Jun N-terminal kinase (JNK) to modulate cytoskeletal elements and control cell polarity.	tmpzr1t_l9r_go_relaxed.owl	non-canonical Wnt signaling pathway|Wnt receptor signaling pathway, planar cell polarity pathway|Wnt receptor signalling pathway, planar cell polarity pathway|PCP pathway|Wnt-activated signaling pathway, planar cell polarity pathway|planar cell polarity pathway|Wnt-JNK signaling pathway|Wnt-PCP signaling pathway													biological_process											owl:Class	
GO:0042302	biolink:NamedThing	structural constituent of cuticle	The action of a molecule that contributes to the structural integrity of a cuticle.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0072298	biolink:NamedThing	regulation of metanephric glomerulus development	Any process that modulates the rate, frequency or extent of metanephric glomerulus development, the progression of the metanephric glomerulus over time from its initial formation until its mature state. The metanephric glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney, or metanephros.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-04-09T05:03:14Z					biological_process											owl:Class	
GO:0001656	biolink:NamedThing	metanephros development	The process whose specific outcome is the progression of the metanephros over time, from its formation to the mature structure. In mammals, the metanephros is the excretory organ of the fetus, which develops into the mature kidney and is formed from the rear portion of the nephrogenic cord. The metanephros is an endocrine and metabolic organ that filters the blood and excretes the end products of body metabolism in the form of urine.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0018884	biolink:NamedThing	carbazole metabolic process	The chemical reactions and pathways involving carbazole, a heterocyclic aromatic compound containing a dibenzopyrrole system that is produced during coal gasification and is present in cigarette smoke. Coal tar produced at high temperature contains an average of 1.5% carbazole. It is used widely in synthesis of dyes, pharmaceuticals, and plastics and is a suspected carcinogen.	tmpzr1t_l9r_go_relaxed.owl	CAR metabolism|CAR metabolic process|carbazole metabolism				UM-BBD_pathwayID:car									biological_process											owl:Class	
GO:0017015	biolink:NamedThing	regulation of transforming growth factor beta receptor signaling pathway	Any process that modulates the frequency, rate or extent of activity of any TGF-beta receptor signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	regulation of transforming growth factor beta receptor signalling pathway|regulation of TGFbeta receptor signaling pathway|regulation of TGF-beta receptor signaling pathway													biological_process											owl:Class	
GO:1903844	biolink:NamedThing	regulation of cellular response to transforming growth factor beta stimulus	Any process that modulates the frequency, rate or extent of cellular response to transforming growth factor beta stimulus.	tmpzr1t_l9r_go_relaxed.owl	regulation of cellular response to TGFbeta stimulus|regulation of cellular response to TGF-beta stimulus							rph	2015-01-23T11:25:11Z					biological_process											owl:Class	
GO:0048076	biolink:NamedThing	regulation of compound eye pigmentation	Any process that modulates the frequency, rate or extent of establishment of a pattern of pigment in the compound eye.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1990631	biolink:NamedThing	ErbB-4 class receptor binding	Binding to the protein-tyrosine kinase receptor ErbB-4/HER4.	tmpzr1t_l9r_go_relaxed.owl	HER4 receptor binding							sl	2015-02-06T23:28:49Z					molecular_function											owl:Class	
GO:0044241	biolink:NamedThing	lipid digestion	The whole of the physical, chemical, and biochemical processes carried out by living organisms to break down ingested lipids into components that may be easily absorbed and directed into metabolism.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0007586	biolink:NamedThing	digestion	The whole of the physical, chemical, and biochemical processes carried out by multicellular organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Digestion									biological_process											owl:Class	
GO:0050976	biolink:NamedThing	detection of mechanical stimulus involved in sensory perception of touch	The series of events involved in the perception of touch in which a mechanical stimulus is received and converted into a molecular signal.	tmpzr1t_l9r_go_relaxed.owl	sensory detection of mechanical stimulus during perception of touch|sensory transduction of mechanical stimulus during perception of touch|perception of touch, sensory transduction of mechanical stimulus|perception of touch, detection of mechanical stimulus|perception of touch, sensory detection of mechanical stimulus|tactition, sensory detection of mechanical stimulus													biological_process											owl:Class	
GO:0050982	biolink:NamedThing	detection of mechanical stimulus	The series of events by which a mechanical stimulus is received and converted into a molecular signal.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0090414	biolink:NamedThing	molybdate ion export from vacuole	The directed movement of molybdate ions out of the vacuole.	tmpzr1t_l9r_go_relaxed.owl								tb	2011-09-15T02:08:43Z					biological_process											owl:Class	
GO:0098661	biolink:NamedThing	inorganic anion transmembrane transport	The process in which an inorganic anion is transported across a membrane.	tmpzr1t_l9r_go_relaxed.owl	inorganic anion membrane transport|transmembrane inorganic anion transport					Note that this term is not intended for use in annotating lateral movement within membranes.								biological_process											owl:Class	
GO:0001926	biolink:NamedThing	positive regulation of B-1 B cell differentiation	Any process that activates or increases the frequency, rate or extent of B-1 B cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	up regulation of B-1 B cell differentiation|positive regulation of B-1 B-lymphocyte differentiation|positive regulation of B-1 B cell development|stimulation of B-1 B cell differentiation|upregulation of B-1 B cell differentiation|positive regulation of B-1 B-cell differentiation|up-regulation of B-1 B cell differentiation|activation of B-1 B cell differentiation|positive regulation of B-1 B lymphocyte differentiation					Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.								biological_process											owl:Class	
GO:0030683	biolink:NamedThing	mitigation of host immune response by virus	A process by which a virus avoids the effects of the host organism's immune response. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	suppression by virus of host immune response|negative regulation by virus of extracellular antiviral response|evasion by virus of host immune response|viral inhibition of intracellular antiviral response|negative regulation of host intracellular antiviral response by virus|suppression of host intracellular antiviral response by virus|negative regulation by virus of intracellular antiviral response|suppression by virus of host extracellular antiviral response|suppression of host extracellular antiviral response by virus|negative regulation of host extracellular antiviral response by virus|suppression by virus of host intracellular antiviral response|evasion or tolerance by virus of host immune response|inhibition of extracellular antiviral response|mitigation by virus of host immune response											GO:0019052|GO:0019053		biological_process											owl:Class	
GO:0019049	biolink:NamedThing	mitigation of host defenses by virus	A process by which a virus avoids or tolerates the effects of its host organism's defenses. Host defenses may be induced by the presence of the virus or may be preformed (e.g. physical barriers). The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	viral host defence evasion|viral host defense evasion|evasion or tolerance of host defenses by virus|evasion of host defenses by virus													biological_process											owl:Class	
GO:0097126	biolink:NamedThing	cyclin B2-CDK1 complex	A protein complex consisting of cyclin B2 and cyclin-dependent kinase 1 (CDK1). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner.	tmpzr1t_l9r_go_relaxed.owl								pr	2011-08-01T01:46:17Z					cellular_component											owl:Class	
GO:0000307	biolink:NamedThing	cyclin-dependent protein kinase holoenzyme complex	Cyclin-dependent protein kinases (CDKs) are enzyme complexes that contain a kinase catalytic subunit associated with a regulatory cyclin partner.	tmpzr1t_l9r_go_relaxed.owl	CDK holoenzyme													cellular_component											owl:Class	
GO:0005521	biolink:NamedThing	lamin binding	Binding to lamin; any of a group of intermediate-filament proteins that form the fibrous matrix on the inner surface of the nuclear envelope.	tmpzr1t_l9r_go_relaxed.owl	lamin/chromatin binding													molecular_function											owl:Class	
GO:1901035	biolink:NamedThing	negative regulation of L-glutamine import across plasma membrane	Any process that stops, prevents or reduces the frequency, rate or extent of L-glutamine import into a cell.	tmpzr1t_l9r_go_relaxed.owl	down regulation of L-glutamine uptake|downregulation of L-glutamine uptake|negative regulation of L-glutamine uptake|downregulation of L-glutamine import|down-regulation of L-glutamine import|inhibition of L-glutamine import|inhibition of L-glutamine uptake|down-regulation of L-glutamine uptake|negative regulation of L-glutamine import|down regulation of L-glutamine import							al	2012-06-21T07:31:48Z					biological_process											owl:Class	
GO:1901034	biolink:NamedThing	regulation of L-glutamine import across plasma membrane	Any process that modulates the frequency, rate or extent of L-glutamine import into cell.	tmpzr1t_l9r_go_relaxed.owl	regulation of L-glutamine import|regulation of L-glutamine uptake							al	2012-06-21T07:31:27Z					biological_process											owl:Class	
GO:0039650	biolink:NamedThing	suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host caspase activity. Caspases are cysteine-type endopeptidases which contribute to the apoptotic process.	tmpzr1t_l9r_go_relaxed.owl	inhibition of host caspases by virus							bf	2012-10-09T15:30:48Z					biological_process											owl:Class	
GO:0019050	biolink:NamedThing	suppression by virus of host apoptotic process	Any viral process that inhibits apoptosis of infected host cells, facilitating prolonged cell survival during viral replication.	tmpzr1t_l9r_go_relaxed.owl	negative regulation by virus of host apoptosis|suppression of apoptosis in host by virus|negative regulation of apoptosis by virus|suppression by virus of host apoptosis													biological_process											owl:Class	
GO:0061913	biolink:NamedThing	positive regulation of growth plate cartilage chondrocyte proliferation	Any process that increases the rate, frequency, or extent of the multiplication or reproduction of chondrocytes in a growing endochondral bone, resulting in the expansion of a cell population.	tmpzr1t_l9r_go_relaxed.owl								dph	2017-07-10T17:31:09Z					biological_process											owl:Class	
GO:0003420	biolink:NamedThing	regulation of growth plate cartilage chondrocyte proliferation	Any process that modulates the rate, frequency, or extent of the multiplication or reproduction of chondrocytes in a growing endochondral bone, resulting in the expansion of a cell population.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-12-22T09:07:40Z					biological_process											owl:Class	
GO:1904901	biolink:NamedThing	positive regulation of myosin II filament organization	Any process that activates or increases the frequency, rate or extent of myosin II filament organization.	tmpzr1t_l9r_go_relaxed.owl	upregulation of myosin II filament organization|activation of myosin II polymerization or depolymerization|activation of myosin II filament assembly or disassembly|up-regulation of myosin II filament assembly or disassembly|upregulation of myosin II polymerization or depolymerization|up-regulation of myosin II filament organization|upregulation of myosin II filament assembly or disassembly|activation of myosin II filament organisation|up regulation of myosin II filament organization|up regulation of myosin II filament assembly or disassembly|positive regulation of myosin II filament organisation|up regulation of myosin II polymerization or depolymerization|positive regulation of myosin II polymerization or depolymerization|activation of myosin II filament organization|up regulation of myosin II filament organisation|upregulation of myosin II filament organisation|up-regulation of myosin II filament organisation|positive regulation of myosin II filament assembly or disassembly|up-regulation of myosin II polymerization or depolymerization							mec	2016-01-15T09:05:02Z					biological_process											owl:Class	
GO:0043519	biolink:NamedThing	regulation of myosin II filament organization	Any process that modulates the frequency, rate or extent of the assembly, arrangement of constituent parts, or disassembly of a bipolar filament composed of myosin II molecules.	tmpzr1t_l9r_go_relaxed.owl	regulation of myosin II filament assembly or disassembly|regulation of myosin II filament organisation													biological_process											owl:Class	
GO:0002579	biolink:NamedThing	positive regulation of antigen processing and presentation	Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation.	tmpzr1t_l9r_go_relaxed.owl	stimulation of antigen processing and presentation|upregulation of antigen processing and presentation|up regulation of antigen processing and presentation|up-regulation of antigen processing and presentation|activation of antigen processing and presentation													biological_process											owl:Class	
GO:0016456	biolink:NamedThing	X chromosome located dosage compensation complex, transcription activating	An RNA-protein complex localized to the X chromosome of males where it is required for the hyper-transcriptional activation of the X chromosome. An example of this is found in Drosophila melanogaster.	tmpzr1t_l9r_go_relaxed.owl	dosage compensation complex													cellular_component											owl:Class	
GO:0046536	biolink:NamedThing	dosage compensation complex	A protein or protein-RNA complex that localizes to one or more of the sex chromosome(s), where it acts to normalize transcription between different sexes.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0018613	biolink:NamedThing	9-fluorenone dioxygenase activity	Catalysis of the reaction: 9-fluorenone + 2 NADPH + O2 = 2 NADP+ + 3,4-dihydroxy-3,4-dihydro-9-fluorenone.	tmpzr1t_l9r_go_relaxed.owl					EC:1.14.12.-|UM-BBD_reactionID:r0409									molecular_function											owl:Class	
GO:0048688	biolink:NamedThing	negative regulation of sprouting of injured axon	Any process that stops, prevents, or reduces the frequency, rate or extent of sprouting of an injured axon.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of sprouting of injured axon|downregulation of sprouting of injured axon|down regulation of sprouting of injured axon|inhibition of sprouting of injured axon													biological_process											owl:Class	
GO:2000092	biolink:NamedThing	positive regulation of mesonephric glomerular mesangial cell proliferation	Any process that activates or increases the frequency, rate or extent of mesonephric glomerular mesangial cell proliferation.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-09-03T06:10:33Z					biological_process											owl:Class	
GO:0004020	biolink:NamedThing	adenylylsulfate kinase activity	Catalysis of the reaction: ATP + adenylylsulfate = ADP + 3'-phosphoadenosine 5'-phosphosulfate.	tmpzr1t_l9r_go_relaxed.owl	adenylyl-sulphate kinase activity|adenosine phosphosulfate kinase activity|adenylylsulfate kinase (phosphorylating)|5'-phosphoadenosine sulfate kinase activity|APS kinase activity|adenosine 5'-phosphosulfate kinase activity|adenosine-5'-phosphosulphate 3'-phosphotransferase activity|adenylyl-sulfate kinase activity|adenosine-5'-phosphosulfate 3'-phosphotransferase activity|adenosine-5'-phosphosulfate-3'-phosphokinase activity|adenosine phosphosulfokinase activity|ATP:adenylyl-sulfate 3'-phosphotransferase activity				Reactome:R-HSA-3560785|RHEA:24152|EC:2.7.1.25|Reactome:R-HSA-174389|MetaCyc:ADENYLYLSULFKIN-RXN									molecular_function											owl:Class	
GO:0051445	biolink:NamedThing	regulation of meiotic cell cycle	Any process that modulates the rate or extent of progression through the meiotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl	meiotic cell cycle regulation|modulation of meiotic cell cycle progression|regulation of meiotic cell cycle progression|regulation of progression through meiotic cell cycle|meiotic cell cycle modulation|meiotic cell cycle regulator													biological_process											owl:Class	
GO:0048150	biolink:NamedThing	behavioral response to ether	Any process that results in a change in the behavior of an organism as a result of an ether stimulus.	tmpzr1t_l9r_go_relaxed.owl	behavioural response to ether													biological_process											owl:Class	
GO:0030534	biolink:NamedThing	adult behavior	Behavior in a fully developed and mature organism.	tmpzr1t_l9r_go_relaxed.owl	adult behavioral response to stimulus|adult behaviour|adult behavioural response to stimulus					See also the biological process term 'behavior ; GO:0007610'.								biological_process											owl:Class	
GO:0051684	biolink:NamedThing	maintenance of Golgi location	Any process in which the Golgi is maintained in a specific location within a cell and prevented from moving elsewhere.	tmpzr1t_l9r_go_relaxed.owl	maintenance of Golgi body localization|maintenance of Golgi localization|maintenance of Golgi apparatus localization													biological_process											owl:Class	
GO:0051645	biolink:NamedThing	Golgi localization	Any process in which the Golgi is transported to, and/or maintained in, a specific location within the cell.	tmpzr1t_l9r_go_relaxed.owl	Golgi localisation|establishment and maintenance of Golgi localization|Golgi apparatus localization|Golgi body localization													biological_process											owl:Class	
GO:0052735	biolink:NamedThing	tRNA (cytosine-3-)-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing 3-methylcytosine.	tmpzr1t_l9r_go_relaxed.owl	transfer ribonucleate cytosine 3-methyltransferase activity|tRNA (cytosine 3)-methyltransferase activity|S-adenosyl-L-methionine:tRNA (cytosine-3-)-methyltransferase activity|tRNA cytosine 3-methyltransferase activity|tRNA cytosine-3-methyltransferase activity|S-adenosyl-L-methionine:tRNA cytosine-3-methyltransferase activity													molecular_function											owl:Class	
GO:0016427	biolink:NamedThing	tRNA (cytosine) methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing methylcytosine.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0120168	biolink:NamedThing	detection of hot stimulus involved in thermoception	The series of events in which a hot stimulus is received and converted into a molecular signal as part of thermoception.	tmpzr1t_l9r_go_relaxed.owl	thermoception, sensory transduction of heat stimulus|thermoception, sensory detection of hot stimulus|sensory transduction of heat stimulus during thermoception|sensory detection of hot stimulus during thermoception|thermoception, sensory transduction of hot stimulus|thermoception, sensory detection of heat stimulus|sensory transduction of hot stimulus during thermoception|sensory detection of heat stimulus during thermoception							krc	2018-05-21T20:35:47Z					biological_process											owl:Class	
GO:0050960	biolink:NamedThing	detection of temperature stimulus involved in thermoception	The series of events in which a temperature stimulus is received and converted into a molecular signal as part of thermoception.	tmpzr1t_l9r_go_relaxed.owl	thermoception, sensory transduction of thermal stimulus|sensory detection of temperature stimulus during thermoception|sensory transduction of temperature stimulus during thermoception|thermoception, sensory detection of temperature stimulus|sensory detection of thermal stimulus during thermoception|thermoception, sensory detection of thermal stimulus|sensory transduction of thermal stimulus during thermoception|thermoception, sensory transduction of temperature stimulus													biological_process											owl:Class	
GO:1900765	biolink:NamedThing	emericellin catabolic process	The chemical reactions and pathways resulting in the breakdown of emericellin.	tmpzr1t_l9r_go_relaxed.owl	Variecoxanthone B catabolism|Variecoxanthone B breakdown|Variecoxanthone B catabolic process|emericellin catabolism|emericellin degradation|emericellin breakdown|Variecoxanthone B degradation							di	2012-06-04T09:18:22Z					biological_process											owl:Class	
GO:1900764	biolink:NamedThing	emericellin metabolic process	The chemical reactions and pathways involving emericellin.	tmpzr1t_l9r_go_relaxed.owl	Variecoxanthone B metabolism|emericellin metabolism|Variecoxanthone B metabolic process							di	2012-06-04T09:17:58Z					biological_process											owl:Class	
GO:0002891	biolink:NamedThing	positive regulation of immunoglobulin mediated immune response	Any process that activates or increases the frequency, rate, or extent of an immunoglobulin mediated immune response.	tmpzr1t_l9r_go_relaxed.owl	upregulation of immunoglobulin mediated immune response|activation of immunoglobulin mediated immune response|up-regulation of immunoglobulin mediated immune response|up regulation of immunoglobulin mediated immune response|stimulation of immunoglobulin mediated immune response													biological_process											owl:Class	
GO:0002714	biolink:NamedThing	positive regulation of B cell mediated immunity	Any process that activates or increases the frequency, rate, or extent of B cell mediated immunity.	tmpzr1t_l9r_go_relaxed.owl	upregulation of B cell mediated immunity|up regulation of B cell mediated immunity|positive regulation of B-lymphocyte mediated immunity|stimulation of B cell mediated immunity|positive regulation of B-cell mediated immunity|positive regulation of B lymphocyte mediated immunity|up-regulation of B cell mediated immunity|activation of B cell mediated immunity													biological_process											owl:Class	
GO:0048164	biolink:NamedThing	distinct antral spaces stage	The stage in oogenesis when the antral spaces become distinct and the first polar body forms.	tmpzr1t_l9r_go_relaxed.owl	mammalian oogenesis stage 7													biological_process											owl:Class	
GO:0022605	biolink:NamedThing	mammalian oogenesis stage	A reproductive process that is a step in the formation and maturation of an ovum or female gamete from a primordial female germ cell.	tmpzr1t_l9r_go_relaxed.owl	mammalian oogenesis process													biological_process											owl:Class	
GO:0086092	biolink:NamedThing	regulation of the force of heart contraction by cardiac conduction	A cardiac conduction process that modulates the extent of heart contraction, changing the force with which blood is propelled.	tmpzr1t_l9r_go_relaxed.owl								dph	2011-11-29T01:26:41Z					biological_process											owl:Class	
GO:0002026	biolink:NamedThing	regulation of the force of heart contraction	Any process that modulates the extent of heart contraction, changing the force with which blood is propelled.	tmpzr1t_l9r_go_relaxed.owl	heart inotropy|cardiac inotropy													biological_process											owl:Class	
GO:1901868	biolink:NamedThing	ecgonine methyl ester catabolic process	The chemical reactions and pathways resulting in the breakdown of ecgonine methyl ester.	tmpzr1t_l9r_go_relaxed.owl	ecgonine methyl ester degradation|ecgonine methyl ester catabolism|ecgonine methyl ester breakdown							ms	2013-02-04T11:58:18Z					biological_process											owl:Class	
GO:0009702	biolink:NamedThing	L-arabinokinase activity	Catalysis of the reaction: L-arabinose + ATP = beta-L-arabinose 1-phosphate + ADP + 2 H(+).	tmpzr1t_l9r_go_relaxed.owl	L-arabinokinase (phosphorylating)|ATP:L-arabinose 1-phosphotransferase activity				KEGG_REACTION:R01754|MetaCyc:L-ARABINOKINASE-RXN|EC:2.7.1.46|RHEA:20153									molecular_function											owl:Class	
GO:0006647	biolink:NamedThing	phosphatidyl-N-monomethylethanolamine biosynthetic process	The chemical reactions and pathways involving phosphatidyl-N-monomethylethanolamine (PMME), a derivative of phosphatidylethanolamine with a methylated amine group.	tmpzr1t_l9r_go_relaxed.owl	phosphatidyl-N-monomethylethanolamine formation|phosphatidyl-N-monomethylethanolamine anabolism|PMME biosynthetic process|PMME biosynthesis|phosphatidyl-N-monomethylethanolamine synthesis|phosphatidyl-N-monomethylethanolamine biosynthesis													biological_process											owl:Class	
GO:0046468	biolink:NamedThing	phosphatidyl-N-monomethylethanolamine metabolic process	The chemical reactions and pathways involving phosphatidyl-N-monomethylethanolamine (PMME), a derivative of phosphatidylethanolamine with a methylated amine group. Present in trace levels in plants and slightly higher in bacteria.	tmpzr1t_l9r_go_relaxed.owl	PMME metabolism|PMME metabolic process|phosphatidyl-N-monomethylethanolamine metabolism													biological_process											owl:Class	
GO:0039596	biolink:NamedThing	modulation by virus of host protein dephosphorylation	Any viral process that modulates the frequency, rate or extent of dephosphorylation of a host protein.	tmpzr1t_l9r_go_relaxed.owl								bf	2012-07-19T11:46:23Z					biological_process											owl:Class	
GO:0035304	biolink:NamedThing	regulation of protein dephosphorylation	Any process that modulates the frequency, rate or extent of removal of phosphate groups from a protein.	tmpzr1t_l9r_go_relaxed.owl	regulation of protein amino acid dephosphorylation													biological_process											owl:Class	
GO:0005743	biolink:NamedThing	mitochondrial inner membrane	The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae.	tmpzr1t_l9r_go_relaxed.owl	mitochondrion inner membrane|inner mitochondrial membrane|inner mitochondrion membrane				NIF_Subcellular:sao1371347282|Wikipedia:Inner_mitochondrial_membrane									cellular_component											owl:Class	
GO:0031966	biolink:NamedThing	mitochondrial membrane	Either of the lipid bilayers that surround the mitochondrion and form the mitochondrial envelope.	tmpzr1t_l9r_go_relaxed.owl					NIF_Subcellular:sao1045389829									cellular_component											owl:Class	
GO:0106090	biolink:NamedThing	positive regulation of cell adhesion involved in sprouting angiogenesis	Any process that activates or increases the frequency, rate or extent of cell adhesion involved in sprouting angiogenesis.	tmpzr1t_l9r_go_relaxed.owl								hjd	2018-01-22T18:31:02Z					biological_process											owl:Class	
GO:0031653	biolink:NamedThing	heat dissipation	Any homeostatic process in which an organism releases excess heat to the environment, thereby lowering its internal temperature.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0001659	biolink:NamedThing	temperature homeostasis	A homeostatic process in which an organism modulates its internal body temperature.	tmpzr1t_l9r_go_relaxed.owl	thermoregulation				Wikipedia:Thermoregulation									biological_process											owl:Class	
GO:1901734	biolink:NamedThing	quercetin biosynthetic process	The chemical reactions and pathways resulting in the formation of quercetin.	tmpzr1t_l9r_go_relaxed.owl	quercetin biosynthesis|quercetin anabolism|quercetin formation|quercetin synthesis							yaf	2013-01-11T10:25:20Z					biological_process											owl:Class	
GO:0051553	biolink:NamedThing	flavone biosynthetic process	The chemical reactions and pathways resulting in the formation of flavones, a class of pigmented plant compounds based on 2-phenyl-4H-1-benzopyran-4-one (2-phenylchromone).	tmpzr1t_l9r_go_relaxed.owl	2-phenylchromone biosynthetic process|2-phenyl-4H-1-benzopyran-4-one biosynthetic process|2-phenyl-4H-1-benzopyran-4-one biosynthesis|2-phenylchromone biosynthesis													biological_process											owl:Class	
GO:1905716	biolink:NamedThing	negative regulation of cornification	Any process that stops, prevents or reduces the frequency, rate or extent of cornification.	tmpzr1t_l9r_go_relaxed.owl	down regulation of cornification|inhibition of cornification|downregulation of cornification|down-regulation of cornification							pga	2016-11-24T13:53:03Z					biological_process											owl:Class	
GO:0043069	biolink:NamedThing	negative regulation of programmed cell death	Any process that stops, prevents, or reduces the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes.	tmpzr1t_l9r_go_relaxed.owl	inhibition of programmed cell death|down regulation of programmed cell death|negative regulation of non-apoptotic programmed cell death|downregulation of programmed cell death|down-regulation of programmed cell death											GO:0043072		biological_process											owl:Class	
GO:0102661	biolink:NamedThing	homogentisate solanyltransferase activity	Catalysis of the reaction: all-trans-nonaprenyl diphosphate + homogentisate + H+ <=> 2-methyl-6-all-trans-nonaprenyl-1,4-benzoquinone + carbon dioxide + diphosphoric acid.	tmpzr1t_l9r_go_relaxed.owl					EC:2.5.1.117|MetaCyc:RXN-2761|RHEA:37995									molecular_function											owl:Class	
GO:0006971	biolink:NamedThing	hypotonic response	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a hypotonic environment, i.e. an environment with a lower concentration of solutes than the organism or cell.	tmpzr1t_l9r_go_relaxed.owl	hypo-osmotic response													biological_process											owl:Class	
GO:0006970	biolink:NamedThing	response to osmotic stress	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell.	tmpzr1t_l9r_go_relaxed.owl	osmotic stress response|osmotic response													biological_process											owl:Class	
GO:1905859	biolink:NamedThing	negative regulation of heparan sulfate proteoglycan binding	Any process that stops, prevents or reduces the frequency, rate or extent of heparan sulfate proteoglycan binding.	tmpzr1t_l9r_go_relaxed.owl	downregulation of heparin proteoglycan binding|negative regulation of heparin proteoglycan binding|inhibition of heparin proteoglycan binding|down regulation of heparan sulfate proteoglycan binding|down regulation of heparin proteoglycan binding|inhibition of heparan sulfate proteoglycan binding|downregulation of heparan sulfate proteoglycan binding|down-regulation of heparin proteoglycan binding|down-regulation of heparan sulfate proteoglycan binding							bc	2017-01-23T14:25:19Z					biological_process											owl:Class	
GO:0036105	biolink:NamedThing	peroxisome membrane class-1 targeting sequence binding	Binding to a class I peroxisomal membrane targeting sequence, any of several sequences of amino acids within a protein that can act as a signal for the localization of the protein into the peroxisome membrane in a PEX19-dependent manner.	tmpzr1t_l9r_go_relaxed.owl	PEX19-dependent mPTS binding|class 1 mPTS binding					Currently identified mPTSs vary greatly in length, and cannot be distinguished by primary structure analysis, suggesting that the peroxisomal sorting information is not contained within a specific amino acid sequence. There do however appear to be two classes of mPTSs: class 1 mPTSs that are bound by PEX19 and imported in a PEX19-dependent manner, and class 2 mPTSs that are not bound by PEX19 and mediate protein import independently of PEX19. The two classes cannot be defined based on their amino acid sequence.		bf	2012-01-27T02:02:22Z					molecular_function											owl:Class	
GO:0033328	biolink:NamedThing	peroxisome membrane targeting sequence binding	Binding to a peroxisomal membrane targeting sequence, any of several sequences of amino acids within a protein that can act as a signal for the localization of the protein into the peroxisome membrane.	tmpzr1t_l9r_go_relaxed.owl	PMP targeting signal (mPTS) binding|PMP targeting signal binding|mPTS binding|peroxisomal membrane protein (PMP) targeting signal (mPTS) binding													molecular_function											owl:Class	
GO:0031820	biolink:NamedThing	P2Y11 nucleotide receptor binding	Binding to a P2Y11 nucleotide receptor.	tmpzr1t_l9r_go_relaxed.owl	P2Y11 nucleotide receptor ligand													molecular_function											owl:Class	
GO:0031811	biolink:NamedThing	G protein-coupled nucleotide receptor binding	Binding to a G protein-coupled (metabotropic) nucleotide receptor.	tmpzr1t_l9r_go_relaxed.owl	metabotropic nucleotide receptor ligand|P2Y receptor binding|metabotropic nucleotide receptor binding|G-protein coupled nucleotide receptor binding													molecular_function											owl:Class	
GO:0046549	biolink:NamedThing	retinal cone cell development	Development of a cone cell, one of the sensory cells in the eye that reacts to the presence of light. Cone cells contain the photopigment iodopsin or cyanopsin and are responsible for photopic (daylight) vision.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0042462	biolink:NamedThing	eye photoreceptor cell development	Development of a photoreceptor, a sensory cell in the eye that reacts to the presence of light. They usually contain a pigment that undergoes a chemical change when light is absorbed, thus stimulating a nerve.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:2000105	biolink:NamedThing	positive regulation of DNA-dependent DNA replication	Any process that activates or increases the frequency, rate or extent of DNA-dependent DNA replication.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-09-15T01:37:10Z					biological_process											owl:Class	
GO:1903814	biolink:NamedThing	regulation of collecting lymphatic vessel constriction	Any process that modulates the frequency, rate or extent of collecting lymphatic vessel constriction.	tmpzr1t_l9r_go_relaxed.owl	regulation of lymphatic vessel myogenic constriction							sl	2015-01-16T17:01:49Z					biological_process											owl:Class	
GO:0102087	biolink:NamedThing	N-benzoyl-L-glutamate synthetase activity	Catalysis of the reaction: benzoate + L-glutamate + ATP <=> H+ + N-benzoyl-L-glutamate + AMP + diphosphoric acid.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-10886									molecular_function											owl:Class	
GO:0009486	biolink:NamedThing	cytochrome bo3 ubiquinol oxidase activity	Catalysis of the reaction: 2 ubiquinol + O2 + 4 H+ = 2 ubiquinone + 2 H2O + 4 H+ [periplasmic space].	tmpzr1t_l9r_go_relaxed.owl	cytochrome bo(3) oxidase|cytochrome o ubiquinol oxidase activity|cytochrome bo oxidase	https://github.com/geneontology/go-ontology/issues/20924			RHEA:30251|TC:3.D.4.5.1|EC:7.1.1.3|MetaCyc:RXN0-5268							GO:0008827		molecular_function											owl:Class	
GO:0060424	biolink:NamedThing	lung field specification	The process that results in the delineation of a specific region of the foregut into the area in which the lung will develop.	tmpzr1t_l9r_go_relaxed.owl	lung specification													biological_process											owl:Class	
GO:0002421	biolink:NamedThing	B cell antigen processing and presentation following pinocytosis	B cell antigen processing and presentation which is initiated by uptake of antigen via pinocytosis.	tmpzr1t_l9r_go_relaxed.owl	B lymphocyte antigen processing and presentation following pinocytosis|B-cell antigen processing and presentation following pinocytosis|B-lymphocyte antigen processing and presentation following pinocytosis													biological_process											owl:Class	
GO:0002746	biolink:NamedThing	antigen processing and presentation following pinocytosis	Antigen processing and presentation which is initiated by uptake of antigen via pinocytosis.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:2000928	biolink:NamedThing	negative regulation of cellodextrin catabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of cellodextrin catabolic process.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of cellodextrin catabolism							tt	2011-08-01T12:41:33Z					biological_process											owl:Class	
GO:0009895	biolink:NamedThing	negative regulation of catabolic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of catabolism|inhibition of catabolic process|negative regulation of degradation|downregulation of catabolic process|negative regulation of breakdown|down-regulation of catabolic process|down regulation of catabolic process													biological_process											owl:Class	
GO:0019209	biolink:NamedThing	kinase activator activity	Binds to and increases the activity of a kinase, an enzyme which catalyzes of the transfer of a phosphate group, usually from ATP, to a substrate molecule.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0032731	biolink:NamedThing	positive regulation of interleukin-1 beta production	Any process that activates or increases the frequency, rate, or extent of interleukin-1 beta production.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of IL-1 beta production|upregulation of interleukin-1 beta production|up-regulation of interleukin-1 beta production|positive regulation of interleukin-1 beta secretion|activation of interleukin-1 beta production|up regulation of interleukin-1 beta production|stimulation of interleukin-1 beta production|positive regulation of interleukin-1 beta biosynthetic process											GO:0050725|GO:0050718		biological_process											owl:Class	
GO:0052841	biolink:NamedThing	inositol bisdiphosphate tetrakisphosphate diphosphatase activity	Catalysis of the reaction: inositol bisdiphosphate tetrakisphosphate + H2O = inositol diphosphate pentakisphosphate + phosphate.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-1855165|Reactome:R-HSA-2023973			ai	2011-11-29T04:14:22Z					molecular_function											owl:Class	
GO:0009069	biolink:NamedThing	serine family amino acid metabolic process	The chemical reactions and pathways involving amino acids of the serine family, comprising cysteine, glycine, homoserine, selenocysteine and serine.	tmpzr1t_l9r_go_relaxed.owl	serine family amino acid metabolism													biological_process											owl:Class	
GO:1901605	biolink:NamedThing	alpha-amino acid metabolic process	The chemical reactions and pathways involving an alpha-amino acid.	tmpzr1t_l9r_go_relaxed.owl	alpha-amino acid metabolism							tb	2012-11-08T17:39:50Z					biological_process											owl:Class	
GO:0032121	biolink:NamedThing	meiotic attachment of telomeric heterochromatin to spindle pole body	The meiotic cell cycle process in which physical connections are formed between telomeric heterochromatin and the spindle pole body, facilitating bouquet formation.	tmpzr1t_l9r_go_relaxed.owl	attachment of telomeres to spindle pole body|attachment of telomeric chromatin to spindle pole body													biological_process											owl:Class	
GO:0003197	biolink:NamedThing	endocardial cushion development	The progression of a cardiac cushion over time, from its initial formation to the mature structure. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-10-08T01:17:43Z					biological_process											owl:Class	
GO:0060485	biolink:NamedThing	mesenchyme development	The process whose specific outcome is the progression of a mesenchymal tissue over time, from its formation to the mature structure. A mesenchymal tissue is made up of loosely packed stellate cells.	tmpzr1t_l9r_go_relaxed.owl	mesenchymal development													biological_process											owl:Class	
GO:0001915	biolink:NamedThing	negative regulation of T cell mediated cytotoxicity	Any process that stops, prevents, or reduces the rate of T cell mediated cytotoxicity.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of T-cell mediated cytolysis|down regulation of T cell mediated cytotoxicity|negative regulation of T cell mediated cell killing|negative regulation of T lymphocyte mediated cytotoxicity|negative regulation of T cell mediated cytolysis|negative regulation of T-lymphocyte mediated cytotoxicity|negative regulation of T-cell mediated cytotoxicity|down-regulation of T cell mediated cytotoxicity|downregulation of T cell mediated cytotoxicity|negative regulation of T cell mediated cell death|negative regulation of T-cell mediated apoptosis|negative regulation of T-cell mediated cell killing|negative regulation of T cell mediated apoptosis|negative regulation of T-cell mediated cell death|inhibition of T cell mediated cytotoxicity													biological_process											owl:Class	
GO:0046315	biolink:NamedThing	phosphocreatine catabolic process	The chemical reactions and pathways resulting in the breakdown of phosphocreatine, a phosphagen of creatine which is synthesized and broken down by creatine phosphokinase.	tmpzr1t_l9r_go_relaxed.owl	phosphocreatine breakdown|phosphocreatine degradation|phosphocreatine catabolism													biological_process											owl:Class	
GO:0042397	biolink:NamedThing	phosphagen catabolic process	The chemical reactions and pathways resulting in the breakdown of phosphagen, any of a group of guanidine phosphates that occur in muscle and can be used to regenerate ATP from ADP during muscular contraction.	tmpzr1t_l9r_go_relaxed.owl	phosphagen degradation|phosphagen catabolism|phosphagen breakdown													biological_process											owl:Class	
GO:0050011	biolink:NamedThing	itaconyl-CoA hydratase activity	Catalysis of the reaction: citramalyl-CoA = itaconyl-CoA + H2O.	tmpzr1t_l9r_go_relaxed.owl	itaconyl coenzyme A hydratase activity|citramalyl-CoA hydro-lyase activity|citramalyl-CoA hydro-lyase (itaconyl-CoA-forming)				EC:4.2.1.56|MetaCyc:ITACONYL-COA-HYDRATASE-RXN|RHEA:13785									molecular_function											owl:Class	
GO:1904857	biolink:NamedThing	regulation of endothelial cell chemotaxis to vascular endothelial growth factor	Any process that modulates the frequency, rate or extent of endothelial cell chemotaxis to vascular endothelial growth factor.	tmpzr1t_l9r_go_relaxed.owl								rph	2015-12-16T11:47:44Z					biological_process											owl:Class	
GO:0097444	biolink:NamedThing	spine apparatus	A specialization of the endomembrane system found in some classes of dendritic spines consisting of two or more closely apposed lamellae with interspersed electron dense material.  The endomembrane component is continuous with the smooth endoplasmic reticulum.	tmpzr1t_l9r_go_relaxed.owl	dense material				NIF_Subcellular:sao725931194			pr	2012-12-06T14:05:58Z					cellular_component											owl:Class	
GO:0043227	biolink:NamedThing	membrane-bounded organelle	Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.	tmpzr1t_l9r_go_relaxed.owl	membrane-enclosed organelle				NIF_Subcellular:sao414196390									cellular_component											owl:Class	
GO:0035173	biolink:NamedThing	histone kinase activity	Catalysis of the transfer of a phosphate group to a histone. Histones are any of a group of water-soluble proteins found in association with the DNA of eukaroytic chromosomes.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0004672	biolink:NamedThing	protein kinase activity	Catalysis of the phosphorylation of an amino acid residue in a protein, usually according to the reaction: a protein + ATP = a phosphoprotein + ADP.	tmpzr1t_l9r_go_relaxed.owl	protamine kinase activity				Reactome:R-HSA-975139|Reactome:R-HSA-9673284|Reactome:R-HSA-156832|MetaCyc:PROTEIN-KINASE-RXN|Reactome:R-HSA-937034|Reactome:R-HSA-9604606	Note that triphosphate is used as a phosphate donor by at least one kinase.						GO:0050222		molecular_function											owl:Class	
GO:0072078	biolink:NamedThing	nephron tubule morphogenesis	The process in which the anatomical structures of a nephron tubule are generated and organized. A nephron tubule is an epithelial tube that is part of the nephron, the functional part of the kidney.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-02-01T02:25:14Z					biological_process											owl:Class	
GO:0061333	biolink:NamedThing	renal tubule morphogenesis	The process in which the renal tubule is generated by specification of cell fate, through the maintenance of cell polarity, regulated cell proliferation and morphogenetic cell rearrangements, shape changes and growth. A renal tubule is a tube that filters, re-absorbs and secretes substances to rid an organism of waste and to play a role in fluid homeostasis.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-09-28T01:43:04Z					biological_process											owl:Class	
GO:0032804	biolink:NamedThing	negative regulation of low-density lipoprotein particle receptor catabolic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of low-density lipoprotein receptors.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of low-density lipoprotein receptor catabolic process|downregulation of low-density lipoprotein receptor catabolic process|negative regulation of low-density lipoprotein receptor catabolism|negative regulation of low-density lipoprotein receptor degradation|negative regulation of low-density lipoprotein receptor catabolic process|negative regulation of low-density lipoprotein receptor breakdown|inhibition of low-density lipoprotein receptor catabolic process|down regulation of low-density lipoprotein receptor catabolic process													biological_process											owl:Class	
GO:0032803	biolink:NamedThing	regulation of low-density lipoprotein particle receptor catabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of low-density lipoprotein particle receptors.	tmpzr1t_l9r_go_relaxed.owl	regulation of low-density lipoprotein receptor catabolic process|regulation of LDLr catabolic process|regulation of low-density lipoprotein receptor degradation|regulation of LDLr catabolism|regulation of low-density lipoprotein receptor catabolism|regulation of low-density lipoprotein receptor breakdown													biological_process											owl:Class	
GO:0098526	biolink:NamedThing	inhibitory neuromuscular junction of somatic myotube	A neuromuscular junction that functions in the inhibition of somatic muscle myotube contraction. Examples of somatic muscle myotubes include the somatic muscle cells of arthropods.	tmpzr1t_l9r_go_relaxed.owl								dos	2013-10-14T12:06:43Z					cellular_component											owl:Class	
GO:0098521	biolink:NamedThing	inhibitory neuromuscular junction	The junction between the axon of a motor neuron and a muscle fiber. In response to the arrival of action potentials, the presynaptic button releases molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane of the muscle fiber, leading to a change in post-synaptic potential that inhibits muscle contraction.	tmpzr1t_l9r_go_relaxed.owl						Inhibitory neuromuscular junctions are found in arthropods but not in vertebrates.		dos	2013-10-14T12:04:08Z					cellular_component											owl:Class	
GO:0060049	biolink:NamedThing	regulation of protein glycosylation	Any process that modulates the frequency, rate or extent of protein glycosylation. Protein glycosylation is the addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid, e.g. the addition of glycan chains to proteins.	tmpzr1t_l9r_go_relaxed.owl	regulation of protein amino acid glycosylation													biological_process											owl:Class	
GO:0099555	biolink:NamedThing	trans-synaptic signaling by nitric oxide, modulating synaptic transmission	Cell-cell signaling between presynapse and postsynapse, via the release and reception of nitric oxide molecules, that modulates the synaptic transmission properties of the synapse.	tmpzr1t_l9r_go_relaxed.owl						Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.								biological_process											owl:Class	
GO:0004622	biolink:NamedThing	lysophospholipase activity	Catalysis of the reaction: 2-lysophosphatidylcholine + H2O = glycerophosphocholine + a carboxylate.	tmpzr1t_l9r_go_relaxed.owl	lysophosphatidase activity|lecitholipase activity|lecithinase B activity|phospholipase B activity|lysolecithinase activity|lysophopholipase L2|lysophosphatidylcholine hydrolase activity|2-lysophosphatidylcholine acylhydrolase activity|lysophospholipase A1|phosphatidase B				RHEA:15177|MetaCyc:LYSOPHOSPHOLIPASE-RXN|Reactome:R-HSA-1482545|Reactome:R-HSA-1482696|Reactome:R-HSA-6814766|Reactome:R-HSA-6814254|Reactome:R-HSA-1482571|EC:3.1.1.5|Reactome:R-HSA-8847912|Reactome:R-HSA-1482685|Reactome:R-HSA-6814778|Reactome:R-HSA-1482612|Reactome:R-HSA-1482629							GO:0045126		molecular_function											owl:Class	
GO:0005858	biolink:NamedThing	axonemal dynein complex	A dynein complex found in eukaryotic cilia and flagella; the motor domain heads interact with adjacent microtubules to generate a sliding force which is converted to a bending motion.	tmpzr1t_l9r_go_relaxed.owl	axonemal dynein heavy chain|axonemal dynein intermediate light chain|axonemal dynein light chain|axonemal dynein intermediate chain													cellular_component											owl:Class	
GO:0030286	biolink:NamedThing	dynein complex	Any of several large complexes that contain two or three dynein heavy chains and several light chains, and have microtubule motor activity.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0008397	biolink:NamedThing	sterol 12-alpha-hydroxylase activity	Catalysis of the reaction: a steroid + donor-H2 + O2 = 12-alpha-hydroxysteroid + H2O.	tmpzr1t_l9r_go_relaxed.owl	cytochrome P450 CYP8B1													molecular_function											owl:Class	
GO:0008395	biolink:NamedThing	steroid hydroxylase activity	Catalysis of the formation of a hydroxyl group on a steroid by incorporation of oxygen from O2.	tmpzr1t_l9r_go_relaxed.owl	cytochrome P450 CYP2G1|olfactory-specific steroid hydroxylase activity				Reactome:R-HSA-193965|Reactome:R-HSA-193143|Reactome:R-HSA-193713|Reactome:R-HSA-193393|Reactome:R-HSA-193780|Reactome:R-HSA-193460|Reactome:R-HSA-192042|Reactome:R-HSA-193497|Reactome:R-HSA-191983|Reactome:R-HSA-193787|Reactome:R-HSA-192123|Reactome:R-HSA-193737|Reactome:R-HSA-193719|Reactome:R-HSA-193060|Reactome:R-HSA-6785245|RHEA:43836|Reactome:R-HSA-193995|Reactome:R-HSA-193792|Reactome:R-HSA-9035960|Reactome:R-HSA-192054|Reactome:R-HSA-5601849|Reactome:R-HSA-6785244|Reactome:R-HSA-191999|Reactome:R-HSA-5602170							GO:0008394		molecular_function											owl:Class	
GO:0043536	biolink:NamedThing	positive regulation of blood vessel endothelial cell migration	Any process that activates or increases the frequency, rate or extent of the migration of the endothelial cells of blood vessels.	tmpzr1t_l9r_go_relaxed.owl	up regulation of blood vessel endothelial cell migration|stimulation of blood vessel endothelial cell migration|upregulation of blood vessel endothelial cell migration|up-regulation of blood vessel endothelial cell migration|activation of blood vessel endothelial cell migration													biological_process											owl:Class	
GO:0043535	biolink:NamedThing	regulation of blood vessel endothelial cell migration	Any process that modulates the frequency, rate or extent of the migration of the endothelial cells of blood vessels.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0002700	biolink:NamedThing	regulation of production of molecular mediator of immune response	Any process that modulates the frequency, rate, or extent of the production of molecular mediator of immune response.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1902641	biolink:NamedThing	regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process	Any process that modulates the frequency, rate or extent of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate degradation|regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolism|regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate breakdown							di	2014-01-21T17:54:14Z					biological_process											owl:Class	
GO:0043972	biolink:NamedThing	histone H3-K23 acetylation	The modification of histone H3 by the addition of an acetyl group to a lysine residue at position 23 of the histone.	tmpzr1t_l9r_go_relaxed.owl	histone H3K23 acetylation|histone H3 acetylation at K23													biological_process											owl:Class	
GO:0043966	biolink:NamedThing	histone H3 acetylation	The modification of histone H3 by the addition of an acetyl group.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0032597	biolink:NamedThing	B cell receptor transport into membrane raft	The directed movement of a B cell receptor into a membrane raft.	tmpzr1t_l9r_go_relaxed.owl	BCR transport into membrane raft|B cell receptor translocation into membrane raft|B cell receptor transport into lipid raft|BCR translocation into membrane raft													biological_process											owl:Class	
GO:0032595	biolink:NamedThing	B cell receptor transport within lipid bilayer	The directed movement of a B cell receptor within a lipid bilayer.	tmpzr1t_l9r_go_relaxed.owl	B cell receptor translocation within membrane|BCR translocation within membrane|BCR transport within lipid bilayer													biological_process											owl:Class	
GO:0032617	biolink:NamedThing	interleukin-14 production	The appearance of interleukin-14 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	tmpzr1t_l9r_go_relaxed.owl	interleukin-14 secretion|interleukin-14 biosynthetic process|IL-14 production											GO:0042232|GO:0072612		biological_process											owl:Class	
GO:0042451	biolink:NamedThing	purine nucleoside biosynthetic process	The chemical reactions and pathways resulting in the formation of any purine nucleoside, one of a family of organic molecules consisting of a purine base covalently bonded to a sugar ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside).	tmpzr1t_l9r_go_relaxed.owl	purine nucleoside biosynthesis|purine nucleoside formation|purine nucleoside anabolism|purine nucleoside synthesis													biological_process											owl:Class	
GO:0042856	biolink:NamedThing	eugenol catabolic process	The chemical reactions and pathways resulting in the breakdown of eugenol, a colorless, aromatic, liquid hydrocarbon (C10H12O2) found in clove oil.	tmpzr1t_l9r_go_relaxed.owl	eugenol degradation|eugenol catabolism|eugenol breakdown|eugenic acid catabolism|4-allyl-2-methoxyphenol catabolism|eugenic acid catabolic process|4-allyl-2-methoxyphenol catabolic process													biological_process											owl:Class	
GO:0140237	biolink:NamedThing	translation at presynapse, modulating chemical synaptic transmission	Translation that occurs at the presynapse, and that modulates chemical synaptic transmission.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/synapse/issues/216				Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.		pg	2018-07-13T13:07:23Z					biological_process											owl:Class	
GO:0140236	biolink:NamedThing	translation at presynapse	Translation that occurs at the presynapse.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/synapse/issues/216				Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.		pg	2018-07-13T13:00:33Z					biological_process											owl:Class	
GO:0090268	biolink:NamedThing	activation of mitotic cell cycle spindle assembly checkpoint	Any process that starts the inactive process of a mitotic cell cycle spindle assembly checkpoint.	tmpzr1t_l9r_go_relaxed.owl								tb	2010-02-05T02:09:44Z					biological_process											owl:Class	
GO:0090267	biolink:NamedThing	positive regulation of mitotic cell cycle spindle assembly checkpoint	Any process that increases the rate, frequency, or extent of the mitotic cell cycle spindle assembly checkpoint, a cell cycle checkpoint that delays the metaphase/anaphase transition of a mitotic nuclear division until the spindle is correctly assembled and chromosomes are attached to the spindle.	tmpzr1t_l9r_go_relaxed.owl								tb	2010-02-05T02:09:44Z					biological_process											owl:Class	
GO:0042930	biolink:NamedThing	enterobactin transport	The directed movement of the siderochrome enterobactin, a cyclic trimer of 2, 3 dihydroxybenzoylserine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	enterochelin transport													biological_process											owl:Class	
GO:0015891	biolink:NamedThing	siderophore transport	The directed movement of siderophores, low molecular weight Fe(III)-chelating substances, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	siderochrome transport|siderophore-iron transport|iron-siderochrome transport|iron-siderophore transport											GO:0015892		biological_process											owl:Class	
GO:0006015	biolink:NamedThing	5-phosphoribose 1-diphosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of 5-phosphoribose 1-diphosphate, also known as 5-phosphoribosyl-1-pyrophosphate.	tmpzr1t_l9r_go_relaxed.owl	5-phosphoribose 1-diphosphate biosynthesis|5-phosphoribose 1-diphosphate anabolism|5-phosphoribose 1-diphosphate formation|5-phosphoribosyl-1-pyrophosphate biosynthesis|5-phosphoribose 1-diphosphate synthesis|5-phosphoribosyl-1-pyrophosphate biosynthetic process|PRPP biosynthetic process				MetaCyc:PWY0-661									biological_process											owl:Class	
GO:0046390	biolink:NamedThing	ribose phosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of ribose phosphate, any phosphorylated ribose sugar.	tmpzr1t_l9r_go_relaxed.owl	ribose phosphate formation|ribose phosphate biosynthesis|ribose phosphate synthesis|ribose phosphate anabolism													biological_process											owl:Class	
GO:0050366	biolink:NamedThing	tyramine N-feruloyltransferase activity	Catalysis of the reaction: feruloyl-CoA + tyramine = CoA + N-feruloyltyramine.	tmpzr1t_l9r_go_relaxed.owl	feruloyl-CoA tyramine N-feruloyl-CoA transferase activity|feruloyltyramine synthase activity|feruloyl-CoA:tyramine N-(hydroxycinnamoyl)transferase activity|tyramine feruloyltransferase activity|tyramine N-feruloyl-CoA transferase activity				MetaCyc:TYRAMINE-N-FERULOYLTRANSFERASE-RXN|EC:2.3.1.110|RHEA:19685									molecular_function											owl:Class	
GO:0033490	biolink:NamedThing	cholesterol biosynthetic process via lathosterol	The chemical reactions and pathways resulting in the formation of cholesterol, cholest-5-en-3 beta-ol, via the intermediate lathosterol.	tmpzr1t_l9r_go_relaxed.owl	cholesterol synthesis via lathosterol|cholesterol anabolism via lathosterol|cholesterol formation via lathosterol|cholesterol biosynthesis via lathosterol				MetaCyc:PWY66-341									biological_process											owl:Class	
GO:0006695	biolink:NamedThing	cholesterol biosynthetic process	The chemical reactions and pathways resulting in the formation of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.	tmpzr1t_l9r_go_relaxed.owl	cholesterol formation|cholesterol biosynthesis|cholesterol synthesis|cholesterol anabolism													biological_process											owl:Class	
GO:0042448	biolink:NamedThing	progesterone metabolic process	The chemical reactions and pathways involving progesterone, a steroid hormone produced in the ovary which prepares and maintains the uterus for pregnancy. Also found in plants.	tmpzr1t_l9r_go_relaxed.owl	progesterone metabolism													biological_process											owl:Class	
GO:0120254	biolink:NamedThing	olefinic compound metabolic process	The chemical reactions and pathways involving an olefinic compound, any compound which contains a carbon-carbon double bond (aka C=C).	tmpzr1t_l9r_go_relaxed.owl	alkene substituted compound metabolic process|alkene substituted compound metabolism	https://github.com/geneontology/go-ontology/issues/19936						krc	2020-09-02T23:13:44Z					biological_process											owl:Class	
GO:0006222	biolink:NamedThing	UMP biosynthetic process	The chemical reactions and pathways resulting in the formation of UMP, uridine monophosphate.	tmpzr1t_l9r_go_relaxed.owl	UMP biosynthesis|UMP formation|UMP synthesis|UMP anabolism													biological_process											owl:Class	
GO:0009220	biolink:NamedThing	pyrimidine ribonucleotide biosynthetic process	The chemical reactions and pathways resulting in the formation of a pyrimidine ribonucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.	tmpzr1t_l9r_go_relaxed.owl	pyrimidine ribonucleotide synthesis|pyrimidine ribonucleotide biosynthesis|pyrimidine ribonucleotide formation|pyrimidine ribonucleotide anabolism				MetaCyc:PWY0-162									biological_process											owl:Class	
GO:1900372	biolink:NamedThing	negative regulation of purine nucleotide biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of purine nucleotide biosynthetic processes.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of purine nucleotide anabolism|inhibition of purine nucleotide formation|down-regulation of purine nucleotide biosynthetic process|down regulation of purine nucleotide formation|downregulation of purine nucleotide biosynthetic process|down-regulation of purine nucleotide anabolism|inhibition of purine nucleotide biosynthesis|downregulation of purine nucleotide synthesis|down regulation of purine nucleotide anabolism|negative regulation of purine nucleotide biosynthesis|downregulation of purine nucleotide formation|down regulation of purine nucleotide biosynthetic process|down-regulation of purine nucleotide formation|down-regulation of purine nucleotide biosynthesis|inhibition of purine nucleotide biosynthetic process|downregulation of purine nucleotide biosynthesis|inhibition of purine nucleotide synthesis|down regulation of purine nucleotide biosynthesis|down regulation of purine nucleotide synthesis|downregulation of purine nucleotide anabolism|down-regulation of purine nucleotide synthesis|inhibition of purine nucleotide anabolism|negative regulation of purine nucleotide formation|negative regulation of purine nucleotide synthesis							krc	2012-04-17T12:32:27Z					biological_process											owl:Class	
GO:1900543	biolink:NamedThing	negative regulation of purine nucleotide metabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of purine nucleotide metabolic process.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of purine metabolic process|down regulation of purine nucleotide metabolism|downregulation of purine nucleotide metabolic process|negative regulation of purine nucleotide metabolism|down-regulation of purine metabolism|inhibition of purine nucleotide metabolic process|negative regulation of purine metabolism|downregulation of purine metabolism|down-regulation of purine nucleotide metabolic process|downregulation of purine nucleotide metabolism|down regulation of purine nucleotide metabolic process|down-regulation of purine nucleotide metabolism|inhibition of purine metabolism|down regulation of purine metabolic process|downregulation of purine metabolic process|inhibition of purine metabolic process|down-regulation of purine metabolic process|down regulation of purine metabolism|inhibition of purine nucleotide metabolism							krc	2012-05-11T05:44:21Z					biological_process											owl:Class	
GO:0048878	biolink:NamedThing	chemical homeostasis	Any biological process involved in the maintenance of an internal steady state of a chemical.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0140108	biolink:NamedThing	high-affinity glucose transmembrane transporter activity	Enables the transfer of glucose from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/14212						pg	2017-10-12T10:06:19Z					molecular_function											owl:Class	
GO:0005355	biolink:NamedThing	glucose transmembrane transporter activity	Enables the transfer of the hexose monosaccharide glucose from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	galactose/glucose (methylgalactoside) porter activity|lactose/glucose efflux transporter activity|glucose permease activity				Reactome:R-HSA-5653873|Reactome:R-HSA-499981							GO:0015579		molecular_function											owl:Class	
GO:1905872	biolink:NamedThing	negative regulation of protein localization to cell leading edge	Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cell leading edge.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of protein localization in cell leading edge|down-regulation of protein localisation in cell leading edge|down regulation of protein localisation to cell leading edge|downregulation of protein localisation to cell leading edge|downregulation of protein localization in cell leading edge|down-regulation of protein localization in cell leading edge|down-regulation of protein localization to cell leading edge|negative regulation of protein localisation to cell leading edge|down regulation of protein localization to cell leading edge|inhibition of protein localisation in cell leading edge|downregulation of protein localisation in cell leading edge|inhibition of protein localization to cell leading edge|downregulation of protein localization to cell leading edge|down regulation of protein localization in cell leading edge|down regulation of protein localisation in cell leading edge|down-regulation of protein localisation to cell leading edge|negative regulation of protein localisation in cell leading edge|inhibition of protein localization in cell leading edge|inhibition of protein localisation to cell leading edge							sl	2017-01-27T19:35:04Z					biological_process											owl:Class	
GO:0001016	biolink:NamedThing	RNA polymerase III transcription regulatory region sequence-specific DNA binding	Binding to a DNA region that controls the transcription of a gene by RNA polymerase III. Binding may occur as a sequence specific interaction or as an interaction observed only once a factor has been recruited to the DNA by other factors.	tmpzr1t_l9r_go_relaxed.owl	RNA polymerase III regulatory region DNA binding							krc	2010-08-19T09:36:17Z					molecular_function											owl:Class	
GO:0000976	biolink:NamedThing	transcription cis-regulatory region binding	Binding to a specific sequence of DNA that is part of a regulatory region that controls transcription of that section of the DNA. The transcribed region might be described as a gene, cistron, or operon.	tmpzr1t_l9r_go_relaxed.owl	transcription regulatory region sequence-specific DNA binding|transcription regulatory region DNA binding|regulatory region DNA binding|bacterial-type RNA polymerase transcription regulatory region sequence-specific DNA binding|eubacterial-type RNA polymerase regulatory region DNA binding|bacterial-type RNA polymerase regulatory region DNA binding|eubacterial-type RNA polymerase regulatory region sequence-specific DNA binding	https://github.com/geneontology/go-ontology/issues/20791|https://github.com/geneontology/go-ontology/issues/19312				Note that this term is meant to also capture non-specific binding to regulatory regions. Also, to minimize ambiguity in the use of the word "promoter" in GO, we have chosen the phrase "transcription regulatory region" to refer to all of the regulatory regions. Regulatory regions in the DNA which control initiation may include the "core promoter" where the basal transcription machinery binds, the "core promoter proximal region" where regulatory factors other than the basal machinery bind. There are also additional regulatory regions, in both the DNA and the RNA transcript, which regulate elongation or termination of transcription.		krc	2010-08-10T02:58:18Z			GO:0000975|GO:0001017|GO:0044212|GO:0000984		molecular_function											owl:Class	
GO:0018152	biolink:NamedThing	peptide cross-linking via 3'-(1'-L-histidyl)-L-tyrosine	The modification of peptidyl-histidine and peptidyl-tyrosine to form a 3'-(1'-L-histidyl)-L-tyrosine protein cross-link.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0270									biological_process											owl:Class	
GO:0018151	biolink:NamedThing	peptide cross-linking via L-histidyl-L-tyrosine	The modification of peptidyl-histidine and peptidyl-tyrosine to form a protein cross-link.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0043521	biolink:NamedThing	regulation of myosin II filament disassembly	Any process that modulates the frequency, rate or extent of the disassembly of a bipolar filament composed of myosin II molecules.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1905625	biolink:NamedThing	negative regulation of L-methionine import across plasma membrane	Any process that stops, prevents or reduces the frequency, rate or extent of L-methionine import across plasma membrane.	tmpzr1t_l9r_go_relaxed.owl								vw	2016-10-29T16:27:38Z					biological_process											owl:Class	
GO:1905624	biolink:NamedThing	regulation of L-methionine import across plasma membrane	Any process that modulates the frequency, rate or extent of L-methionine import across plasma membrane.	tmpzr1t_l9r_go_relaxed.owl								vw	2016-10-29T16:27:29Z					biological_process											owl:Class	
GO:0015101	biolink:NamedThing	organic cation transmembrane transporter activity	Enables the transfer of organic cations from one side of a membrane to the other. Organic cations are atoms or small molecules with a positive charge that contain carbon in covalent linkage.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-561054|Reactome:R-HSA-561072|Reactome:R-HSA-549279|Reactome:R-HSA-549129|Reactome:R-HSA-549304|Reactome:R-HSA-549322|Reactome:R-HSA-2161500									molecular_function											owl:Class	
GO:0018467	biolink:NamedThing	formaldehyde dehydrogenase activity	Catalysis of the reaction: formaldehyde + H(2)O + NAD(+) = formate + 2 H(+) + NADH.	tmpzr1t_l9r_go_relaxed.owl	glutathione-independent formaldehyde dehydrogenase activity|formaldehyde:NAD+ oxidoreductase activity				KEGG_REACTION:R00604|RHEA:16425|MetaCyc:FORMALDEHYDE-DEHYDROGENASE-RXN|EC:1.2.1.46|UM-BBD_reactionID:r0240									molecular_function											owl:Class	
GO:0009658	biolink:NamedThing	chloroplast organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the chloroplast.	tmpzr1t_l9r_go_relaxed.owl	chloroplast organization and biogenesis|chloroplast organisation													biological_process											owl:Class	
GO:0009657	biolink:NamedThing	plastid organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a plastid.	tmpzr1t_l9r_go_relaxed.owl	plastid organization and biogenesis|plastid organisation													biological_process											owl:Class	
GO:0002890	biolink:NamedThing	negative regulation of immunoglobulin mediated immune response	Any process that stops, prevents, or reduces the frequency, rate, or extent of an immunoglobulin mediated immune response.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of immunoglobulin mediated immune response|downregulation of immunoglobulin mediated immune response|down regulation of immunoglobulin mediated immune response|inhibition of immunoglobulin mediated immune response													biological_process											owl:Class	
GO:0002713	biolink:NamedThing	negative regulation of B cell mediated immunity	Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell mediated immunity.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of B-lymphocyte mediated immunity|negative regulation of B lymphocyte mediated immunity|negative regulation of B-cell mediated immunity|inhibition of B cell mediated immunity|down-regulation of B cell mediated immunity|downregulation of B cell mediated immunity|down regulation of B cell mediated immunity													biological_process											owl:Class	
GO:0051948	biolink:NamedThing	negative regulation of glutamate uptake involved in transmission of nerve impulse	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of L-glutamate into a neuron or glial cell.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of glutamate uptake during transmission of nerve impulse|downregulation of glutamate uptake during transmission of nerve impulse|negative regulation of glutamate uptake involved in conduction of nerve impulse|negative regulation of glutamate reuptake|negative regulation of glutamate uptake during transmission of nerve impulse|down regulation of glutamate uptake during transmission of nerve impulse|inhibition of glutamate uptake during transmission of nerve impulse													biological_process											owl:Class	
GO:0051946	biolink:NamedThing	regulation of glutamate uptake involved in transmission of nerve impulse	Any process that modulates the frequency, rate or extent of the directed movement of L-glutamate into a neuron or glial cell.	tmpzr1t_l9r_go_relaxed.owl	regulation of L-glutamate reuptake|regulation of glutamate uptake involved in conduction of nerve impulse|regulation of L-glutamate uptake during transmission of nerve impulse|regulation of glutamate uptake during transmission of nerve impulse|regulation of glutamate reuptake													biological_process											owl:Class	
GO:0019536	biolink:NamedThing	vibriobactin metabolic process	The chemical reactions and pathways involving vibriobactin, the major siderophore produced by Vibrio cholerae.	tmpzr1t_l9r_go_relaxed.owl	vibriobactin metabolism													biological_process											owl:Class	
GO:0009237	biolink:NamedThing	siderophore metabolic process	The chemical reactions and pathways involving siderophores, low molecular weight Fe(III)-chelating substances made by aerobic or facultatively anaerobic bacteria, especially when growing under iron deficient conditions. The complexes of Fe(3+)-siderophores have very high stability constants and are taken up by specific transport systems by microorganisms; the subsequent release of iron requires enzymatic action.	tmpzr1t_l9r_go_relaxed.owl	siderochrome metabolism|siderophore metabolism|siderochrome metabolic process													biological_process											owl:Class	
GO:0045644	biolink:NamedThing	negative regulation of eosinophil differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of eosinophil differentiation.	tmpzr1t_l9r_go_relaxed.owl	downregulation of eosinophil differentiation|inhibition of eosinophil differentiation|down regulation of eosinophil differentiation|down-regulation of eosinophil differentiation													biological_process											owl:Class	
GO:0099590	biolink:NamedThing	neurotransmitter receptor internalization	A receptor-mediated endocytosis process that results in the internalization of a neurotransmitter receptor.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0031623	biolink:NamedThing	receptor internalization	A receptor-mediated endocytosis process that results in the movement of receptors from the plasma membrane to the inside of the cell. The process begins when cell surface receptors are monoubiquitinated following ligand-induced activation. Receptors are subsequently taken up into endocytic vesicles from where they are either targeted to the lysosome or vacuole for degradation or recycled back to the plasma membrane.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1900380	biolink:NamedThing	negative regulation of asperthecin biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of asperthecin biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	inhibition of asperthecin biosynthetic process|downregulation of asperthecin synthesis|inhibition of asperthecin formation|down regulation of asperthecin synthesis|negative regulation of asperthecin biosynthesis|down regulation of asperthecin biosynthesis|inhibition of asperthecin synthesis|down-regulation of asperthecin synthesis|negative regulation of asperthecin formation|down regulation of asperthecin biosynthetic process|downregulation of asperthecin biosynthetic process|down-regulation of asperthecin biosynthesis|down regulation of asperthecin formation|down-regulation of asperthecin formation|negative regulation of asperthecin synthesis|inhibition of asperthecin biosynthesis|downregulation of asperthecin biosynthesis|downregulation of asperthecin formation|down-regulation of asperthecin biosynthetic process							di	2012-04-17T01:58:37Z					biological_process											owl:Class	
GO:1900379	biolink:NamedThing	regulation of asperthecin biosynthetic process	Any process that modulates the frequency, rate or extent of asperthecin biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of asperthecin formation|regulation of asperthecin synthesis|regulation of asperthecin biosynthesis							di	2012-04-17T01:58:27Z					biological_process											owl:Class	
GO:0048649	biolink:NamedThing	caste determination, influence by genetic factors	The process in which individuals, having the potential to develop any of several distinct developmental paths, have their individual developmental fate determined in response to genetic cues. Individuals with distinct developmental fates perform different functions in a colony of social insects.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0048652	biolink:NamedThing	polyphenic determination, influence by genetic factors	The process in which individuals that have the potential to develop any of several possible distinct developmental paths have their individual developmental fates determined in response to genetic cues.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0050798	biolink:NamedThing	activated T cell proliferation	The expansion of a T cell population following activation by an antigenic stimulus.	tmpzr1t_l9r_go_relaxed.owl	proliferation of activated T cells|activated T-lymphocyte proliferation|activated T lymphocyte proliferation|activated T-cell proliferation					Note that this term refers to the proliferation of previously activated T cells; it is to be used for gene products involved in T cell proliferation following an antigenic stimulus, including both proteins internal to the T cell and external factors, such as IL-2, which specifically promote proliferation of activated T cells.								biological_process											owl:Class	
GO:0042098	biolink:NamedThing	T cell proliferation	The expansion of a T cell population by cell division. Follows T cell activation.	tmpzr1t_l9r_go_relaxed.owl	T lymphocyte proliferation|T-cell proliferation|T-lymphocyte proliferation											GO:0042111		biological_process											owl:Class	
GO:0005388	biolink:NamedThing	P-type calcium transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Ca2+(in) = ADP + phosphate + Ca2+(out).	tmpzr1t_l9r_go_relaxed.owl	calcium-transporting ATPase activity|sarco(endo)plasmic reticulum Ca2+-ATPase|Ca(2+)-transporting ATPase activity|ATP-dependent calcium transmembrane transporter activity|calcium pump|Ca2+-transporting ATPase activity|calcium transporting ATPase activity|calcium efflux ATPase|ATPase-coupled calcium transmembrane transporter activity|calcium-translocating P-type ATPase activity|calcium transmembrane transporter activity, phosphorylative mechanism				EC:7.2.2.10|Reactome:R-HSA-418309|MetaCyc:3.6.3.8-RXN|Reactome:R-HSA-936883|Reactome:R-HSA-418365|Reactome:R-HSA-427910|RHEA:18105									molecular_function											owl:Class	
GO:0019829	biolink:NamedThing	ATPase-coupled cation transmembrane transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + cation(out) = ADP + phosphate + cation(in).	tmpzr1t_l9r_go_relaxed.owl	ATP-dependent cation transmembrane transporter activity|plasma membrane cation-transporting ATPase|cation-transporting ATPase activity|cation ABC transporter				Reactome:R-HSA-5251989|Reactome:R-HSA-5692480									molecular_function											owl:Class	
GO:0072723	biolink:NamedThing	cellular response to amitrole	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amitrole stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to 3-amino-1,2,4-triazole							mah	2012-05-31T10:51:52Z					biological_process											owl:Class	
GO:0072722	biolink:NamedThing	response to amitrole	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amitrole stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to 3-amino-1,2,4-triazole							mah	2012-05-31T10:51:45Z					biological_process											owl:Class	
GO:2000872	biolink:NamedThing	positive regulation of progesterone secretion	Any process that activates or increases the frequency, rate or extent of progesterone secretion.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-07-26T08:51:22Z					biological_process											owl:Class	
GO:2000196	biolink:NamedThing	positive regulation of female gonad development	Any process that activates or increases the frequency, rate or extent of female gonad development.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of ovarian development|positive regulation of ovary development							yaf	2010-10-19T10:45:41Z					biological_process											owl:Class	
GO:2000304	biolink:NamedThing	positive regulation of ceramide biosynthetic process	Any process that activates or increases the frequency, rate or extent of ceramide biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of ceramide synthesis|positive regulation of ceramide formation|positive regulation of ceramide biosynthesis|positive regulation of ceramide anabolism							dph	2011-01-04T02:37:32Z					biological_process											owl:Class	
GO:0006233	biolink:NamedThing	dTDP biosynthetic process	The chemical reactions and pathways resulting in the formation of dTDP, deoxyribosylthymine diphosphate (2'-deoxyribosylthymine5'-diphosphate).	tmpzr1t_l9r_go_relaxed.owl	dTDP anabolism|dTDP formation|dTDP synthesis|dTDP biosynthesis													biological_process											owl:Class	
GO:0009197	biolink:NamedThing	pyrimidine deoxyribonucleoside diphosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of pyrimidine deoxyribonucleoside diphosphate, a compound consisting of a pyrimidine base linked to a deoxyribose sugar esterified with diphosphate on the sugar.	tmpzr1t_l9r_go_relaxed.owl	pyrimidine deoxyribonucleoside diphosphate biosynthesis|pyrimidine deoxyribonucleoside diphosphate synthesis|pyrimidine deoxyribonucleoside diphosphate anabolism|pyrimidine deoxyribonucleoside diphosphate formation													biological_process											owl:Class	
GO:0018475	biolink:NamedThing	trans-2-methyl-5-isopropylhexa-2,5-dienal dehydrogenase activity	Catalysis of the reaction: trans-2-methyl-5-isopropylhexa-2,5-dienal + NAD+ + H2O = NADH + H+ + trans-2-methyl-5-isopropylhexa-2,5-dienoic acid.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0745									molecular_function											owl:Class	
GO:2000134	biolink:NamedThing	negative regulation of G1/S transition of mitotic cell cycle	Any signalling pathway that decreases or inhibits the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G1 phase to S phase of the mitotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-09-29T09:38:51Z					biological_process											owl:Class	
GO:1901991	biolink:NamedThing	negative regulation of mitotic cell cycle phase transition	Any process that stops, prevents or reduces the frequency, rate or extent of mitotic cell cycle phase transition.	tmpzr1t_l9r_go_relaxed.owl	downregulation of mitotic cell cycle phase transition|down-regulation of mitotic cell cycle phase transition|inhibition of mitotic cell cycle phase transition|down regulation of mitotic cell cycle phase transition							jl	2013-03-19T16:14:46Z					biological_process											owl:Class	
GO:0044506	biolink:NamedThing	modulation of glucagon-like peptide receptor 1 activity in other organism	The process in which an organism effects a change in the activity of a glucagon-like peptide receptor 1 in a second organism.	tmpzr1t_l9r_go_relaxed.owl	regulation of glucagon-like peptide receptor activity in other organism							jl	2012-02-23T04:29:14Z					biological_process											owl:Class	
GO:0044504	biolink:NamedThing	modulation of receptor activity in other organism	The process in which an organism effects a change in the activity of a receptor in a second organism.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-02-23T04:21:41Z					biological_process											owl:Class	
GO:1900190	biolink:NamedThing	regulation of single-species biofilm formation	Any process that modulates the frequency, rate or extent of single-species biofilm formation.	tmpzr1t_l9r_go_relaxed.owl								di	2012-03-19T12:42:04Z					biological_process											owl:Class	
GO:0002803	biolink:NamedThing	positive regulation of antibacterial peptide production	Any process that activates or increases the frequency, rate, or extent of antibacterial peptide production.	tmpzr1t_l9r_go_relaxed.owl	up regulation of antibacterial peptide production|upregulation of antibacterial peptide production|up-regulation of antibacterial peptide production|activation of antibacterial peptide production|stimulation of antibacterial peptide production													biological_process											owl:Class	
GO:1900426	biolink:NamedThing	positive regulation of defense response to bacterium	Any process that activates or increases the frequency, rate or extent of defense response to bacterium.	tmpzr1t_l9r_go_relaxed.owl	upregulation of defence response to bacterium|activation of defense response to bacterium|up regulation of defence response to bacteria|up-regulation of defense response to bacteria|positive regulation of defense response to bacteria|up-regulation of antibacterial peptide activity|activation of defense response to bacteria|activation of resistance response to pathogenic bacterium|upregulation of defense response to bacteria|activation of defence response to bacteria|up regulation of defense response to bacterium|up regulation of defence response to bacterium|positive regulation of defence response to bacterium|activation of antibacterial peptide activity|up-regulation of defense response to bacterium|upregulation of defence response to bacteria|activation of defence response to bacterium|positive regulation of defence response to bacteria|activation of resistance response to pathogenic bacteria|up-regulation of defence response to bacteria|up regulation of defense response to bacteria|upregulation of antibacterial peptide activity|up regulation of antibacterial peptide activity|up-regulation of defence response to bacterium|upregulation of defense response to bacterium|positive regulation of defense response to bacterium, incompatible interaction|positive regulation of antibacterial peptide activity							dhl	2012-04-24T10:13:13Z			GO:1902479		biological_process											owl:Class	
GO:0004604	biolink:NamedThing	phosphoadenylyl-sulfate reductase (thioredoxin) activity	Catalysis of the reaction: adenosine 3',5'-diphosphate + H(+) + sulfite + thioredoxin disulfide = 3'-phospho-5'-adenylyl sulfate + thioredoxin. Thioredoxin disulfide is the oxidized form of thioredoxin; 3'-phosphoadenosine 5'-phosphosulfate is also known as PAPS.	tmpzr1t_l9r_go_relaxed.owl	3'-phosphoadenylylsulfate reductase activity|thioredoxin:adenosine 3'-phosphate 5'-phosphosulfate reductase activity|PAdoPS reductase activity|PAPS reductase activity|PAPS reductase, thioredoxin-dependent activity|adenosine 3',5'-bisphosphate,sulfite:thioredoxin-disulfide oxidoreductase (3'-phosphoadenosine-5'-phosphosulfate-forming)|phosphoadenosine-phosphosulfate reductase activity|phosphoadenylyl-sulphate reductase (thioredoxin) activity|PAPS sulfotransferase activity|thioredoxin:3'-phospho-adenylylsulfate reductase activity|adenosine 3',5'-bisphosphate,sulfite:oxidized-thioredoxin oxidoreductase (3'-phosphoadenosine-5'-phosphosulfate-forming)				RHEA:11724|MetaCyc:1.8.4.8-RXN|EC:1.8.4.8|KEGG_REACTION:R02021									molecular_function											owl:Class	
GO:0016671	biolink:NamedThing	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which a sulfur-containing group acts as a hydrogen or electron donor and reduces disulfide.	tmpzr1t_l9r_go_relaxed.owl	oxidoreductase activity, acting on sulphur group of donors, disulphide as acceptor				EC:1.8.4.-									molecular_function											owl:Class	
GO:0018425	biolink:NamedThing	O3-(N-acetylglucosamine-1-phosphoryl)-L-serine biosynthetic process	The chemical reactions and pathways resulting in the formation of O3-(N-acetylglucosamine-1-phosphoryl)-L-serine. The recovery of O-phosphorylserine from acid hydrolysates suggests N-acetylglucosamine-1-phosphate residues are esterified to peptidyl serines through phosphoester bonds.	tmpzr1t_l9r_go_relaxed.owl	O3-(N-acetylglucosamine-1-phosphoryl)-L-serine biosynthesis|O3-(N-acetylglucosamine-1-phosphoryl)-L-serine synthesis|O3-(N-acetylglucosamine-1-phosphoryl)-L-serine anabolism|O3-(N-acetylglucosamine-1-phosphoryl)-L-serine formation				RESID:AA0296									biological_process											owl:Class	
GO:0046349	biolink:NamedThing	amino sugar biosynthetic process	The chemical reactions and pathways resulting in the formation of any amino sugar, sugars containing an amino group in place of a hydroxyl group.	tmpzr1t_l9r_go_relaxed.owl	amino sugar anabolism|aminosaccharide biosynthesis|amino sugar formation|amino sugar synthesis|amino sugar biosynthesis|aminosaccharide biosynthetic process													biological_process											owl:Class	
GO:0016414	biolink:NamedThing	O-octanoyltransferase activity	Catalysis of the transfer of an octanoyl group to an oxygen atom on the acceptor molecule.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0008374	biolink:NamedThing	O-acyltransferase activity	Catalysis of the transfer of an acyl group to an oxygen atom on the acceptor molecule.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-1482850|Reactome:R-HSA-5483229|Reactome:R-HSA-162683|Reactome:R-HSA-1482781|Reactome:R-HSA-1482861|Reactome:R-HSA-1482867|Reactome:R-HSA-422104|Reactome:R-HSA-5358343|Reactome:R-HSA-3238694|Reactome:R-HSA-422017|Reactome:R-HSA-1482775									molecular_function											owl:Class	
GO:0009900	biolink:NamedThing	dehiscence	The opening of an anther, fruit or other structure, which permits the escape of reproductive bodies contained within it.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Dehiscence_(botany)									biological_process											owl:Class	
GO:0017083	biolink:NamedThing	4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase activity	Catalysis of the reaction: GDP-beta-L-fucose + beta-D-galactosyl-(1,4)-N-acetyl-D-glucosaminyl-R = GDP + 1,4-beta-D-galactosyl-(1,4)-[alpha-L-fucosyl-(1,3)]-N-acetyl-D-glucosaminyl-R.	tmpzr1t_l9r_go_relaxed.owl	plasma alpha-3-fucosyltransferase activity|guanosine diphosphofucose-glucoside alpha-1->3-fucosyltransferase activity|GDP-L-fucose:1,4-beta-D-galactosyl-N-acetyl-D-glucosaminyl-R 3-L-fucosyltransferase activity|guanosine diphosphofucose-glucoside alpha1->3-fucosyltransferase activity|GDP-beta-L-fucose:1,4-beta-D-galactosyl-N-acetyl-D-glucosaminyl-R 3-L-fucosyltransferase activity|Lewis-negative alpha-3-fucosyltransferase activity|galactoside 3-fucosyltransferase activity|GDP-beta-L-fucose:1,4-beta-D-galactosyl-N-acetyl-D-glucosaminyl-R 3-alpha-L-fucosyltransferase activity|galactoside 3-L-fucosyltransferase activity				EC:2.4.1.152|RHEA:14257|MetaCyc:GALACTOSIDE-3-FUCOSYLTRANSFERASE-RXN									molecular_function											owl:Class	
GO:0046920	biolink:NamedThing	alpha-(1->3)-fucosyltransferase activity	Catalysis of the transfer of an L-fucosyl group from GDP-beta-L-fucose to an acceptor molecule to form an alpha-(1->3) linkage.	tmpzr1t_l9r_go_relaxed.owl	alpha-(1,3)-fucosyltransferase activity|alpha-1,3-fucosyltransferase activity|alpha(1,3)-fucosyltransferase activity				Reactome:R-HSA-9605609|Reactome:R-HSA-9605682|Reactome:R-HSA-9605644|Reactome:R-HSA-9603984									molecular_function											owl:Class	
GO:0071264	biolink:NamedThing	positive regulation of translational initiation in response to starvation	Any process that activates or increases the frequency, rate or extent of translation initiation, as a result of deprivation of nourishment.	tmpzr1t_l9r_go_relaxed.owl	activation of translation initiation in response to starvation|positive regulation of translational initiation in response to nutrient starvation|upregulation of translation initiation in response to starvation|up regulation of translation initiation in response to starvation|up-regulation of translation initiation in response to starvation|stimulation of translation initiation in response to starvation							mah	2009-12-08T05:35:45Z					biological_process											owl:Class	
GO:0042811	biolink:NamedThing	pheromone biosynthetic process	The chemical reactions and pathways resulting in the formation of pheromones, a substance that is secreted and released by an organism and detected by a second organism of the same or a closely related species, in which it causes a specific reaction, such as a definite behavioral reaction or a developmental process.	tmpzr1t_l9r_go_relaxed.owl	pheromone synthesis|pheromone formation|pheromone biosynthesis|pheromone anabolism													biological_process											owl:Class	
GO:0042810	biolink:NamedThing	pheromone metabolic process	The chemical reactions and pathways involving pheromones, a substance that is secreted and released by an organism and detected by a second organism of the same or a closely related species, in which it causes a specific reaction, such as a definite behavioral reaction or a developmental process.	tmpzr1t_l9r_go_relaxed.owl	pheromone metabolism													biological_process											owl:Class	
GO:0047980	biolink:NamedThing	hippurate hydrolase activity	Catalysis of the reaction: N-benzoylglycine + H(2)O = benzoate + glycine.	tmpzr1t_l9r_go_relaxed.owl	hippuricase activity|benzoylglycine amidohydrolase activity|N-benzoylamino-acid amidohydrolase activity				RHEA:10424|MetaCyc:HIPPURATE-HYDROLASE-RXN|KEGG_REACTION:R01424|EC:3.5.1.32									molecular_function											owl:Class	
GO:0061025	biolink:NamedThing	membrane fusion	The membrane organization process that joins two lipid bilayers to form a single membrane.	tmpzr1t_l9r_go_relaxed.owl	single-organism membrane fusion|cellular membrane fusion				Wikipedia:Lipid_bilayer_fusion			jl	2010-02-08T02:48:06Z			GO:0006944|GO:0044801		biological_process											owl:Class	
GO:0061024	biolink:NamedThing	membrane organization	A process which results in the assembly, arrangement of constituent parts, or disassembly of a membrane. A membrane is a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.	tmpzr1t_l9r_go_relaxed.owl	cellular membrane organisation|cellular membrane organization|single-organism membrane organization|membrane organization and biogenesis|membrane organisation							jl	2010-02-08T02:43:11Z			GO:0016044|GO:0044802		biological_process											owl:Class	
GO:0034903	biolink:NamedThing	endosulfan ether monooxygenase activity	Catalysis of the reaction: endosulfan ether + O2 + 2 H+ + 2 e- = endosulfan hydroxyether + H2O.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r1413									molecular_function											owl:Class	
GO:0090654	biolink:NamedThing	basolateral recycling endosome	Tubulo-vesicular structure located in the basolateral cytoplasm that participates in basolateral cargo recycling in polarized epithelial cells.	tmpzr1t_l9r_go_relaxed.owl								tb	2015-07-01T15:46:19Z					cellular_component											owl:Class	
GO:0055037	biolink:NamedThing	recycling endosome	An organelle consisting of a network of tubules that functions in targeting molecules, such as receptors transporters and lipids, to the plasma membrane.	tmpzr1t_l9r_go_relaxed.owl	endosome recycling compartment|ERC|endosomal recycling compartment													cellular_component											owl:Class	
GO:1905803	biolink:NamedThing	negative regulation of cellular response to manganese ion	Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to manganese ion.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of cellular response to manganese|downregulation of cellular response to manganese ion|down-regulation of cellular response to manganese ion|inhibition of cellular response to manganese ion|down regulation of cellular response to manganese|down regulation of cellular response to manganese ion|downregulation of cellular response to manganese|negative regulation of cellular response to manganese|inhibition of cellular response to manganese							pga	2017-01-11T14:59:48Z					biological_process											owl:Class	
GO:1900245	biolink:NamedThing	positive regulation of MDA-5 signaling pathway	Any process that activates or increases the frequency, rate or extent of MDA-5 signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of melanoma differentiation-associated gene 5 signaling pathway|up regulation of melanoma differentiation-associated gene 5 signaling pathway|up-regulation of MDA-5 signaling pathway|up regulation of MDA-5 signaling pathway|positive regulation of MDA5 signaling pathway|activation of IFIH1 signaling pathway|up-regulation of MDA5 signaling pathway|positive regulation of melanoma differentiation-associated gene 5 signaling pathway|activation of MDA-5 signaling pathway|activation of melanoma differentiation-associated gene 5 signaling pathway|positive regulation of MDA-5 signalling pathway|upregulation of MDA-5 signaling pathway|positive regulation of IFIH1 signaling pathway|upregulation of melanoma differentiation-associated gene 5 signaling pathway|upregulation of MDA5 signaling pathway|up-regulation of IFIH1 signaling pathway|upregulation of IFIH1 signaling pathway|up regulation of MDA5 signaling pathway|up regulation of IFIH1 signaling pathway|activation of MDA5 signaling pathway							ss	2012-04-02T10:55:38Z					biological_process											owl:Class	
GO:0002699	biolink:NamedThing	positive regulation of immune effector process	Any process that activates or increases the frequency, rate, or extent of an immune effector process.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of immune effector process|stimulation of immune effector process|activation of immune effector process|up regulation of immune effector process|upregulation of immune effector process													biological_process											owl:Class	
GO:1904917	biolink:NamedThing	L-arginine transmembrane transport from lysosomal lumen to cytosol	The directed movement of L-arginine across a membrane from lysosomal lumen to cytosol.	tmpzr1t_l9r_go_relaxed.owl	transmembrane L-arginine transport from lysosomal lumen to cytosol							kmv	2016-01-21T16:27:48Z					biological_process											owl:Class	
GO:2000007	biolink:NamedThing	negative regulation of metanephric comma-shaped body morphogenesis	Any process that stops, prevents, or reduces the frequency, rate or extent of metanephric comma-shaped body morphogenesis.	tmpzr1t_l9r_go_relaxed.owl								jl	2010-07-30T02:17:17Z					biological_process											owl:Class	
GO:0045595	biolink:NamedThing	regulation of cell differentiation	Any process that modulates the frequency, rate or extent of cell differentiation, the process in which relatively unspecialized cells acquire specialized structural and functional features.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0019449	biolink:NamedThing	L-cysteine catabolic process to hypotaurine	The chemical reactions and pathways resulting in the breakdown of L-cysteine into other compounds, including hypotaurine.	tmpzr1t_l9r_go_relaxed.owl	L-cysteine degradation to hypotaurine|L-cysteine breakdown to hypotaurine													biological_process											owl:Class	
GO:0019448	biolink:NamedThing	L-cysteine catabolic process	The chemical reactions and pathways resulting in the breakdown of L-cysteine, the L-enantiomer of 2-amino-3-mercaptopropanoic acid, i.e. (2R)-2-amino-3-mercaptopropanoic acid.	tmpzr1t_l9r_go_relaxed.owl	L-cysteine degradation|L-cysteine catabolism|L-cysteine breakdown													biological_process											owl:Class	
GO:0006556	biolink:NamedThing	S-adenosylmethionine biosynthetic process	The chemical reactions and pathways resulting in the formation of S-adenosylmethionine, S-(5'-adenosyl)-L-methionine, an important intermediate in one-carbon metabolism.	tmpzr1t_l9r_go_relaxed.owl	S-adenosyl methionine biosynthesis|S-adenosylmethionine formation|SAM biosynthetic process|S-adenosyl methionine biosynthetic process|S-adenosylmethionine synthesis|S-adenosylmethionine anabolism|S-adenosylmethionine biosynthesis				MetaCyc:SAM-PWY									biological_process											owl:Class	
GO:0046500	biolink:NamedThing	S-adenosylmethionine metabolic process	The chemical reactions and pathways involving S-adenosylmethionine, S-(5'-adenosyl)-L-methionine, an important intermediate in one-carbon metabolism.	tmpzr1t_l9r_go_relaxed.owl	S-adenosyl methionine metabolism|S-adenosylmethionine metabolism|SAM metabolic process|S-adenosyl methionine metabolic process													biological_process											owl:Class	
GO:0043934	biolink:NamedThing	sporulation	The process whose specific outcome is the progression of a spore over time, from its initiation to the mature structure. A spore is a structure that can be used for dissemination, for survival of adverse conditions because of its heat and dessication resistance, and/or for reproduction.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Spore									biological_process											owl:Class	
GO:0097374	biolink:NamedThing	sensory neuron axon guidance	The process in which the migration of an axon growth cone of a sensory neuron is directed to a specific target site in response to a combination of attractive and repulsive cues. A sensory neuron is an afferent neuron conveying sensory impulses.	tmpzr1t_l9r_go_relaxed.owl								pr	2012-10-01T10:16:22Z					biological_process											owl:Class	
GO:0007411	biolink:NamedThing	axon guidance	The chemotaxis process that directs the migration of an axon growth cone to a specific target site in response to a combination of attractive and repulsive cues.	tmpzr1t_l9r_go_relaxed.owl	axon chemotaxis|axon growth cone guidance|axon pathfinding				Wikipedia:Axon_guidance							GO:0008040		biological_process											owl:Class	
GO:0052805	biolink:NamedThing	imidazole-containing compound catabolic process	The chemical reactions and pathways resulting in the breakdown of imidazoles, five-membered organic heterocycle containing two nitrogen atoms at positions 1 and 3, or any of its derivatives; compounds containing an imidazole skeleton.	tmpzr1t_l9r_go_relaxed.owl	imidazole degradation|imidazole breakdown|imidazole catabolism													biological_process											owl:Class	
GO:0072667	biolink:NamedThing	maintenance of protein location in vacuole	Any process in which a protein is maintained in a specific location in a vacuole, and is prevented from moving elsewhere.	tmpzr1t_l9r_go_relaxed.owl								mah	2011-02-14T02:56:57Z					biological_process											owl:Class	
GO:0070756	biolink:NamedThing	positive regulation of interleukin-35 production	Any process that activates or increases the frequency, rate, or extent of interleukin-35 production.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of IL-35 production|up-regulation of interleukin-35 production|positive regulation of interleukin-35 biosynthetic process|upregulation of interleukin-35 production|up regulation of interleukin-35 production|activation of interleukin-35 production|stimulation of interleukin-35 production							mah	2009-06-23T01:39:45Z			GO:0070752		biological_process											owl:Class	
GO:0099100	biolink:NamedThing	G-protein gated cation channel activity	A cation channel activity that is gated by binding of a G-protein beta-gamma dimer.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:2000900	biolink:NamedThing	cyclodextrin metabolic process	The chemical reactions and pathways involving a cyclodextrin.	tmpzr1t_l9r_go_relaxed.owl	cyclodextrin metabolism							jl	2011-07-28T03:19:11Z					biological_process											owl:Class	
GO:0044042	biolink:NamedThing	glucan metabolic process	The chemical reactions and pathways involving glucans, polysaccharides consisting only of glucose residues.	tmpzr1t_l9r_go_relaxed.owl	glucan metabolism													biological_process											owl:Class	
GO:0072532	biolink:NamedThing	tri-(feruloyl or hydroxyferuloyl) spermidine meta-hydroxylase activity	Catalysis of the meta-hydroxylation of any of the three phenolic rings on triferuloyl spermidine or any of its mono- or di-(hydroxyferuloyl)-spermidine derivatives.	tmpzr1t_l9r_go_relaxed.owl						Note that the overall reaction representing three successive executions of this activity is N1,N5,N10-triferuloyl spermidine + 3 NADPH + 3 O2 = N1,N5,N10-tri-(hydroxyferuloyl)-spermidine + 3 NADP+ + 3 H2O; this corresponds to the MetaCyc reaction RXN-11262 (http://biocyc.org/META/NEW-IMAGE?type=REACTION&object=RXN-11262) and the KEGG reaction R08986 (http://www.genome.jp/dbget-bin/www_bget?rn:R08986).		mah	2011-01-12T01:54:31Z					molecular_function											owl:Class	
GO:0002597	biolink:NamedThing	positive regulation of antigen processing and presentation of peptide antigen via MHC class Ib	Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class Ib.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of antigen processing and presentation of peptide antigen via MHC class Ib|up regulation of antigen processing and presentation of peptide antigen via MHC class Ib|activation of antigen processing and presentation of peptide antigen via MHC class Ib|stimulation of antigen processing and presentation of peptide antigen via MHC class Ib|upregulation of antigen processing and presentation of peptide antigen via MHC class Ib|positive regulation of peptide antigen processing and presentation via MHC class Ib													biological_process											owl:Class	
GO:0002594	biolink:NamedThing	positive regulation of antigen processing and presentation via MHC class Ib	Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of antigen via MHC class Ib.	tmpzr1t_l9r_go_relaxed.owl	up regulation of antigen processing and presentation via MHC class Ib|upregulation of antigen processing and presentation via MHC class Ib|stimulation of antigen processing and presentation via MHC class Ib|activation of antigen processing and presentation via MHC class Ib|up-regulation of antigen processing and presentation via MHC class Ib													biological_process											owl:Class	
GO:1903948	biolink:NamedThing	negative regulation of atrial cardiac muscle cell action potential	Any process that stops, prevents or reduces the frequency, rate or extent of atrial cardiac muscle cell action potential.	tmpzr1t_l9r_go_relaxed.owl	downregulation of atrial cardiac muscle cell action potential|down-regulation of atrial cardiac muscle cell action potential|inhibition of atrial cardiac muscle cell action potential|down regulation of atrial cardiac muscle cell action potential							nc	2015-02-20T14:36:33Z					biological_process											owl:Class	
GO:0045759	biolink:NamedThing	negative regulation of action potential	Any process that stops, prevents, or reduces the frequency, rate or extent of action potential creation, propagation or termination. This typically occurs via modulation of the activity or expression of voltage-gated ion channels.	tmpzr1t_l9r_go_relaxed.owl	downregulation of action potential|inhibition of action potential|down-regulation of action potential|down regulation of action potential													biological_process											owl:Class	
GO:0086089	biolink:NamedThing	voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization	Enables the transmembrane transfer of a potassium ion by a voltage-gated channel through the plasma membrane of an atrial cardiomyocyte contributing to the repolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.	tmpzr1t_l9r_go_relaxed.owl	voltage-gated potassium channel activity involved in atrial cardiomyocyte action potential repolarization							dph	2011-11-22T01:33:01Z					molecular_function											owl:Class	
GO:0086008	biolink:NamedThing	voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization	Enables the transmembrane transfer of a potassium ion by a voltage-gated channel through the plasma membrane of a cardiac muscle cell contributing to the repolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.	tmpzr1t_l9r_go_relaxed.owl								tb	2011-11-10T08:38:09Z					molecular_function											owl:Class	
GO:2000608	biolink:NamedThing	positive regulation of cell proliferation involved in mesonephros development	Any process that activates or increases the frequency, rate or extent of cell proliferation involved in mesonephros development.	tmpzr1t_l9r_go_relaxed.owl								yaf	2011-04-18T08:42:25Z					biological_process											owl:Class	
GO:2000606	biolink:NamedThing	regulation of cell proliferation involved in mesonephros development	Any process that modulates the frequency, rate or extent of cell proliferation involved in mesonephros development.	tmpzr1t_l9r_go_relaxed.owl								yaf	2011-04-18T08:42:19Z					biological_process											owl:Class	
GO:0006002	biolink:NamedThing	fructose 6-phosphate metabolic process	The chemical reactions and pathways involving fructose 6-phosphate, also known as F6P. The D-enantiomer is an important intermediate in glycolysis, gluconeogenesis, and fructose metabolism.	tmpzr1t_l9r_go_relaxed.owl	fructose 6-phosphate metabolism													biological_process											owl:Class	
GO:0016998	biolink:NamedThing	cell wall macromolecule catabolic process	The chemical reactions and pathways resulting in the breakdown of macromolecules that form part of a cell wall.	tmpzr1t_l9r_go_relaxed.owl	cell wall breakdown|cellular cell wall macromolecule degradation|cell wall degradation|cell wall catabolism|cellular cell wall macromolecule catabolism|cellular cell wall macromolecule breakdown|cellular cell wall macromolecule catabolic process											GO:0044039		biological_process											owl:Class	
GO:0071190	biolink:NamedThing	protocadherin-alpha-v7-protocadherin-gamma-b2 complex	A protein complex that contains the cell adhesion molecules protocadherin-alpha-v7 and protocadherin-gamma-b2, and is involved in the regulation of protein localization to the plasma membrane.	tmpzr1t_l9r_go_relaxed.owl	Pcdha7-Pcdhgb4 complex							mah	2009-11-23T04:30:12Z					cellular_component											owl:Class	
GO:0071183	biolink:NamedThing	protocadherin-alpha-protocadherin-gamma complex	A protein complex that contains two cell adhesion molecules, a protocadherin-alpha and a protocadherin-gamma, and is involved in the regulation of protein localization to the plasma membrane.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-11-23T04:10:30Z					cellular_component											owl:Class	
GO:0098861	biolink:NamedThing	actin filament bundle of filopodium	A parallel bundle of actin filaments that is part of filopodium. Filaments are oriented such that the plus (barbed) ends are at the tip of the protrusion, capped by a tip complex.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0098859	biolink:NamedThing	actin filament bundle of actin-based cell projection	A bundle of cross-linked actin filaments that is part of an actin-based cell protrusion, in which filaments are oriented such that the plus (barbed) ends are at the tip of the protrusion, capped by a tip complex which stabilizes the filaments.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0033352	biolink:NamedThing	UDP-D-apiose biosynthetic process	The chemical reactions and pathways resulting in the formation of UDP-D-apiose, uridinediphosphoapicose, a substance composed of apiose in glycosidic linkage with uridine diphosphate.	tmpzr1t_l9r_go_relaxed.owl	UDP-D-apiose biosynthesis|UDP-D-apiose formation|UDP-D-apiose anabolism|UDP-D-apiose synthesis				MetaCyc:PWY-4821|MetaCyc:PWY-5113									biological_process											owl:Class	
GO:0009226	biolink:NamedThing	nucleotide-sugar biosynthetic process	The chemical reactions and pathways resulting in the formation of nucleotide-sugars, any nucleotide-carbohydrate in which the distal phosphoric residue of a nucleoside 5'-diphosphate is in glycosidic linkage with a monosaccharide or monosaccharide derivative.	tmpzr1t_l9r_go_relaxed.owl	nucleotide-sugar biosynthesis|nucleotide-sugar anabolism|nucleotide-sugar formation|nucleotide-sugar synthesis													biological_process											owl:Class	
GO:0035965	biolink:NamedThing	cardiolipin acyl-chain remodeling	Remodeling the acyl chains of premature (de novo synthesized) cardiolipin (1,3-bis(3-phosphatidyl)glycerol), through sequential deacylation and re-acylation reactions, to generate mature cardiolipin containing high-levels of unsaturated fatty acids.	tmpzr1t_l9r_go_relaxed.owl	cardiolipin maturation|diphosphatidylglycerol remodeling|cardiolipin acyl-chain remodelling							bf	2011-08-03T11:17:49Z					biological_process											owl:Class	
GO:0032048	biolink:NamedThing	cardiolipin metabolic process	The chemical reactions and pathways involving cardiolipin, 1,3-bis(3-phosphatidyl)glycerol.	tmpzr1t_l9r_go_relaxed.owl	diphosphatidylglycerol metabolic process|diphosphatidylglycerol metabolism|cardiolipin metabolism													biological_process											owl:Class	
GO:0018301	biolink:NamedThing	iron incorporation into iron-sulfur cluster via tris-L-cysteinyl-L-cysteine persulfido-bis-L-glutamato-L-histidino tetrairon	The incorporation of iron into an iron-sulfur cluster by tris-L-cysteinyl-L-cysteine persulfido-bis-L-glutamato-L-histidino tetrairon.	tmpzr1t_l9r_go_relaxed.owl	iron incorporation into iron-sulphur cluster via tris-L-cysteinyl-L-cysteine persulphido-bis-L-glutamato-L-histidino tetrairon				RESID:AA0268									biological_process											owl:Class	
GO:0097244	biolink:NamedThing	flavonol binding	Binding to a flavonol, a flavonoid that contains a 3-hydroxy-2-phenylchromen-4-one backbone.	tmpzr1t_l9r_go_relaxed.owl								pr	2012-02-17T03:50:45Z					molecular_function											owl:Class	
GO:0097243	biolink:NamedThing	flavonoid binding	Binding to a flavonoid, a compound containing two or more aromatic rings, each bearing at least one aromatic hydroxyl and connected with a carbon bridge.	tmpzr1t_l9r_go_relaxed.owl								pr	2012-02-17T03:49:16Z					molecular_function											owl:Class	
GO:0045586	biolink:NamedThing	regulation of gamma-delta T cell differentiation	Any process that modulates the frequency, rate or extent of gamma-delta T cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	regulation of gamma-delta T cell development|regulation of gamma-delta T-lymphocyte differentiation|regulation of gamma-delta T-cell differentiation|regulation of gamma-delta T lymphocyte differentiation					Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.								biological_process											owl:Class	
GO:0045580	biolink:NamedThing	regulation of T cell differentiation	Any process that modulates the frequency, rate or extent of T cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	regulation of T lymphocyte differentiation|regulation of T cell development|regulation of T-cell differentiation|regulation of T-lymphocyte differentiation					Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.								biological_process											owl:Class	
GO:0033658	biolink:NamedThing	modification by symbiont of host chloroplast thylakoid	The process in which an organism effects a change in the structure or function of the host cell chloroplast thylakoid. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0033657	biolink:NamedThing	modification by symbiont of host chloroplast part	The process in which an organism effects a change in the structure or function of a component of the host cell chloroplast. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1900668	biolink:NamedThing	negative regulation of endocrocin biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of endocrocin biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	downregulation of endocrocin formation|negative regulation of endocrocin anabolism|downregulation of endocrocin biosynthetic process|down-regulation of endocrocin synthesis|down-regulation of endocrocin biosynthetic process|downregulation of endocrocin biosynthesis|inhibition of endocrocin formation|down regulation of endocrocin formation|downregulation of endocrocin anabolism|inhibition of endocrocin anabolism|negative regulation of endocrocin synthesis|downregulation of endocrocin synthesis|down-regulation of endocrocin formation|down-regulation of endocrocin anabolism|negative regulation of endocrocin formation|down-regulation of endocrocin biosynthesis|inhibition of endocrocin biosynthesis|negative regulation of endocrocin biosynthesis|down regulation of endocrocin biosynthetic process|down regulation of endocrocin synthesis|inhibition of endocrocin synthesis|inhibition of endocrocin biosynthetic process|down regulation of endocrocin anabolism|down regulation of endocrocin biosynthesis							di	2012-05-22T04:16:25Z					biological_process											owl:Class	
GO:0032722	biolink:NamedThing	positive regulation of chemokine production	Any process that activates or increases the frequency, rate, or extent of chemokine production.	tmpzr1t_l9r_go_relaxed.owl	upregulation of chemokine production|positive regulation of chemokine secretion|activation of chemokine production|up-regulation of chemokine production|positive regulation of chemokine biosynthetic process|stimulation of chemokine production|up regulation of chemokine production							tb	2009-12-18T11:28:00Z			GO:0090197|GO:0045080		biological_process											owl:Class	
GO:1903256	biolink:NamedThing	selenoneine metabolic process	The chemical reactions and pathways involving selenoneine.	tmpzr1t_l9r_go_relaxed.owl	L-selenoneine metabolic process|selenoneine metabolism							mah	2014-08-06T09:14:24Z					biological_process											owl:Class	
GO:0006577	biolink:NamedThing	amino-acid betaine metabolic process	The chemical reactions and pathways involving any betaine, the N-trimethyl derivative of an amino acid.	tmpzr1t_l9r_go_relaxed.owl	betaine metabolism|betaine metabolic process													biological_process											owl:Class	
GO:0001813	biolink:NamedThing	regulation of antibody-dependent cellular cytotoxicity	Any process that modulates the frequency, rate, or extent of antibody-dependent cellular cytotoxicity.	tmpzr1t_l9r_go_relaxed.owl	regulation of antibody dependent cell death|regulation of antibody-dependent cell killing|regulation of antibody dependent cell killing|regulation of antibody-dependent cell death													biological_process											owl:Class	
GO:0001910	biolink:NamedThing	regulation of leukocyte mediated cytotoxicity	Any process that modulates the frequency, rate, or extent of leukocyte mediated cytotoxicity.	tmpzr1t_l9r_go_relaxed.owl	regulation of leucocyte mediated cytotoxicity|regulation of immune cell mediated cell death|regulation of immune cell mediated cell killing|regulation of immune cell mediated cytotoxicity													biological_process											owl:Class	
GO:0046405	biolink:NamedThing	glycerol dehydratase activity	Catalysis of the reaction: glycerol = 3-hydroxypropanal + H2O.	tmpzr1t_l9r_go_relaxed.owl	glycerol dehydrase activity|glycerol hydro-lyase (3-hydroxypropanal-forming)|glycerol hydro-lyase activity				MetaCyc:GLYCEROL-DEHYDRATASE-RXN|RHEA:19765|EC:4.2.1.30									molecular_function											owl:Class	
GO:0110014	biolink:NamedThing	negative regulation of aggregation involved in sorocarp development	Any process that decreases the frequency, rate or extent of aggregation involved in sorocarp development. Aggregation involved in sorocarp development is the process whose specific outcome is the progression of the aggregate over time, from its formation to the point when a slug is formed. Aggregate development begins in response to starvation and continues by the chemoattractant-mediated movement of cells toward each other. The aggregate is a multicellular structure that gives rise to the slug.	tmpzr1t_l9r_go_relaxed.owl								kmv	2017-05-10T12:53:12Z					biological_process											owl:Class	
GO:1902814	biolink:NamedThing	positive regulation of BMP signaling pathway involved in determination of lateral mesoderm left/right asymmetry	Any process that activates or increases the frequency, rate or extent of BMP signaling pathway involved in determination of lateral mesoderm left/right asymmetry.	tmpzr1t_l9r_go_relaxed.owl	activation of BMP signaling pathway involved in determination of lateral mesoderm left/right asymmetry|up-regulation of BMP signaling pathway involved in determination of lateral mesoderm left/right asymmetry|up regulation of BMP signaling pathway involved in determination of lateral mesoderm left/right asymmetry|up regulation of BMP signaling pathway involved in lateral mesoderm left/right asymmetry determination|up-regulation of BMP signalling pathway involved in determination of lateral mesoderm left/right asymmetry|upregulation of BMP signaling pathway involved in lateral mesoderm left/right asymmetry determination|activation of BMP signaling pathway involved in lateral mesoderm left/right asymmetry determination|up-regulation of BMP signaling pathway involved in lateral mesoderm left/right asymmetry determination|upregulation of BMP signalling pathway involved in determination of lateral mesoderm left/right asymmetry|activation of BMP signalling pathway involved in determination of lateral mesoderm left/right asymmetry|up regulation of BMP signalling pathway involved in determination of lateral mesoderm left/right asymmetry|positive regulation of BMP signalling pathway involved in determination of lateral mesoderm left/right asymmetry|positive regulation of BMP signaling pathway involved in lateral mesoderm left/right asymmetry determination|upregulation of BMP signaling pathway involved in determination of lateral mesoderm left/right asymmetry							mr	2014-03-26T21:18:56Z					biological_process											owl:Class	
GO:0035944	biolink:NamedThing	perforin production	The appearance of a perforin protein due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	tmpzr1t_l9r_go_relaxed.owl						Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.		bf	2011-07-27T11:44:21Z					biological_process											owl:Class	
GO:0002440	biolink:NamedThing	production of molecular mediator of immune response	The synthesis or release of any molecular mediator of the immune response, resulting in an increase in its intracellular or extracellular levels.	tmpzr1t_l9r_go_relaxed.owl	production of cellular mediator of immune response					Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.								biological_process											owl:Class	
GO:0020009	biolink:NamedThing	microneme	A small, elongated secretory organelle that forms part of the apical complex, located along the main axis of an apicomplexan parasite cell within the extreme apical region and at the periphery under the inner membrane complex. Of the specialized secretory compartments identified in apicomplexans, micronemes discharge their contents first, during initial contact of the parasite's apical pole with the host cell surface. Micronemal proteins function during parasite attachment and penetration into the target cell.	tmpzr1t_l9r_go_relaxed.owl	sarconeme				Wikipedia:Microneme									cellular_component											owl:Class	
GO:0043231	biolink:NamedThing	intracellular membrane-bounded organelle	Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.	tmpzr1t_l9r_go_relaxed.owl	intracellular membrane-enclosed organelle													cellular_component											owl:Class	
GO:0035833	biolink:NamedThing	berbamunine biosynthetic process	The chemical reactions and pathways resulting in the formation of berbamunine, an isoquinoline alkaloid.	tmpzr1t_l9r_go_relaxed.owl	berbamunine formation|berbamunine anabolism|berbamunine synthesis|berbamunine biosynthesis							bf	2011-05-04T03:12:03Z					biological_process											owl:Class	
GO:0035832	biolink:NamedThing	berbamunine metabolic process	The chemical reactions and pathways involving berbamunine, an isoquinoline alkaloid.	tmpzr1t_l9r_go_relaxed.owl	berbamunine metabolism							bf	2011-05-04T03:11:18Z					biological_process											owl:Class	
GO:0120093	biolink:NamedThing	regulation of peptidyl-lysine crotonylation	Any process that modulates the frequency, rate or extent of crotonylation of a lysine residue in a protein.	tmpzr1t_l9r_go_relaxed.owl								krc	2017-08-22T20:25:51Z					biological_process											owl:Class	
GO:1901578	biolink:NamedThing	negative regulation of alkane biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of alkane biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	down regulation of alkane biosynthetic process|downregulation of alkane biosynthetic process|inhibition of alkane biosynthesis|down-regulation of alkane formation|downregulation of alkane synthesis|downregulation of alkane anabolism|negative regulation of alkane anabolism|downregulation of alkane biosynthesis|down regulation of alkane biosynthesis|inhibition of alkane formation|negative regulation of alkane biosynthesis|down-regulation of alkane synthesis|inhibition of alkane anabolism|down-regulation of alkane biosynthesis|down-regulation of alkane anabolism|down regulation of alkane formation|inhibition of alkane synthesis|negative regulation of alkane synthesis|down-regulation of alkane biosynthetic process|down regulation of alkane synthesis|inhibition of alkane biosynthetic process|down regulation of alkane anabolism|downregulation of alkane formation|negative regulation of alkane formation							dhl	2012-11-05T21:54:11Z					biological_process											owl:Class	
GO:1901577	biolink:NamedThing	regulation of alkane biosynthetic process	Any process that modulates the frequency, rate or extent of alkane biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of alkane anabolism|regulation of alkane biosynthesis|regulation of alkane formation|regulation of alkane synthesis							dhl	2012-11-05T21:54:06Z					biological_process											owl:Class	
GO:0098688	biolink:NamedThing	parallel fiber to Purkinje cell synapse	An excitatory synapse formed by the parallel fibers of granule cells synapsing onto the dendrites of Purkinje cells.	tmpzr1t_l9r_go_relaxed.owl								dos	2017-02-21T18:32:05Z					cellular_component											owl:Class	
GO:0060076	biolink:NamedThing	excitatory synapse	A synapse in which an action potential in the presynaptic cell increases the probability of an action potential occurring in the postsynaptic cell.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Excitatory_synapse									cellular_component											owl:Class	
GO:0006562	biolink:NamedThing	proline catabolic process	The chemical reactions and pathways resulting in the breakdown of proline (pyrrolidine-2-carboxylic acid), a chiral, cyclic, nonessential alpha-amino acid found in peptide linkage in proteins.	tmpzr1t_l9r_go_relaxed.owl	proline breakdown|proline degradation|proline catabolism													biological_process											owl:Class	
GO:0009065	biolink:NamedThing	glutamine family amino acid catabolic process	The chemical reactions and pathways resulting in the breakdown of amino acids of the glutamine family, comprising arginine, glutamate, glutamine and proline.	tmpzr1t_l9r_go_relaxed.owl	glutamine family amino acid catabolism|glutamine family amino acid breakdown|glutamine family amino acid degradation													biological_process											owl:Class	
GO:0060685	biolink:NamedThing	regulation of prostatic bud formation	Any process that modulates the rate, frequency, or extent of prostatic bud formation, the morphogenetic process in which a region of the fetal urogenital sinus epithelium is specified to become the prostate, resulting in prostate bud outgrowth.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-06-05T12:29:26Z					biological_process											owl:Class	
GO:0102652	biolink:NamedThing	gibberellin A9,2-oxoglutarate:oxygen oxidoreductase activity	Catalysis of the reaction: gibberellin A9 + 2-oxoglutarate + O2 <=> gibberellin A51 + succinate + carbon dioxide.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-171									molecular_function											owl:Class	
GO:0048790	biolink:NamedThing	maintenance of presynaptic active zone structure	A process which maintains the organization and the arrangement of proteins at the active zone to ensure the fusion and docking of vesicles and the release of neurotransmitters.	tmpzr1t_l9r_go_relaxed.owl	maintenance of pre-synaptic active zone structure													biological_process											owl:Class	
GO:0099558	biolink:NamedThing	maintenance of synapse structure	A process that preserves the structural organistation and orientation of a synaptic cellular component such as the synaptic cytoskeleton and molecular scaffolds.	tmpzr1t_l9r_go_relaxed.owl	synaptic maintenance													biological_process											owl:Class	
GO:0022843	biolink:NamedThing	voltage-gated cation channel activity	Enables the transmembrane transfer of a cation by a voltage-gated channel. A cation is a positively charged ion. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-2534378|Reactome:R-HSA-6788999									molecular_function											owl:Class	
GO:0005244	biolink:NamedThing	voltage-gated ion channel activity	Enables the transmembrane transfer of an ion by a voltage-gated channel. An ion is an atom or group of atoms carrying an electric charge by virtue of having gained or lost one or more electrons. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.	tmpzr1t_l9r_go_relaxed.owl	voltage gated ion channel activity|voltage-dependent ion channel activity													molecular_function											owl:Class	
GO:1904757	biolink:NamedThing	positive regulation of gut granule assembly	Any process that activates or increases the frequency, rate or extent of gut granule assembly.	tmpzr1t_l9r_go_relaxed.owl	activation of gut granule biogenesis|positive regulation of gut granule biogenesis|upregulation of gut granule biogenesis|upregulation of gut granule assembly|activation of gut granule assembly|up regulation of gut granule assembly|up regulation of gut granule formation|up regulation of gut granule biogenesis|up-regulation of gut granule biogenesis|upregulation of gut granule formation|up-regulation of gut granule assembly|activation of gut granule formation|up-regulation of gut granule formation|positive regulation of gut granule formation							ah	2015-10-21T08:43:57Z					biological_process											owl:Class	
GO:1904755	biolink:NamedThing	regulation of gut granule assembly	Any process that modulates the frequency, rate or extent of gut granule assembly.	tmpzr1t_l9r_go_relaxed.owl	regulation of gut granule biogenesis|regulation of gut granule formation							ah	2015-10-21T08:43:44Z					biological_process											owl:Class	
GO:0106016	biolink:NamedThing	positive regulation of inflammatory response to wounding	Any process that activates or increases the frequency, rate or extent of the inflammatory response to wounding.	tmpzr1t_l9r_go_relaxed.owl								hjd	2017-04-28T20:16:31Z					biological_process											owl:Class	
GO:1903036	biolink:NamedThing	positive regulation of response to wounding	Any process that activates or increases the frequency, rate or extent of response to wounding.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of physiological response to wounding|up regulation of physiological response to wounding|upregulation of response to wounding|positive regulation of physiological response to wounding|up regulation of response to wounding|up-regulation of response to wounding|activation of response to wounding|activation of physiological response to wounding|upregulation of physiological response to wounding							kmv	2014-05-18T01:28:58Z					biological_process											owl:Class	
GO:0019179	biolink:NamedThing	dTDP-4-amino-4,6-dideoxy-D-glucose transaminase activity	Catalysis of the reaction: dTDP-4-amino-4,6-dideoxy-D-glucose + 2-oxoglutarate = dTDP-4-dehydro-6-deoxy-D-glucose + L-glutamate.	tmpzr1t_l9r_go_relaxed.owl	dTDP-4-amino-4,6-dideoxy-D-glucose aminotransferase activity|TDP-4-oxo-6-deoxy-D-glucose transaminase activity|thymidine diphospho-4-keto-6-deoxy-D-glucose-glutamic transaminase activity|dTDP-4-amino-4,6-dideoxy-D-glucose:2-oxoglutarate aminotransferase activity|thymidine diphospho-4-amino-6-deoxyglucose aminotransferase activity|TDP-4-keto-6-deoxy-D-glucose transaminase activity|thymidine diphospho-4-keto-6-deoxy-D-glucose transaminase activity|thymidine diphospho-4-amino-4,6-dideoxyglucose aminotransferase activity				MetaCyc:2.6.1.33-RXN|EC:2.6.1.33|RHEA:19085									molecular_function											owl:Class	
GO:0036349	biolink:NamedThing	galactose-specific flocculation	The non-sexual aggregation of single-celled organisms mediated by the binding of cell wall proteins on one cell to galactose residues on the other.	tmpzr1t_l9r_go_relaxed.owl	cell-cell adhesion involved in galactose-specific flocculation							bf	2012-09-19T10:56:16Z			GO:0098611		biological_process											owl:Class	
GO:0000128	biolink:NamedThing	flocculation	The reversible, non-sexual aggregation of single-celled organisms in suspension to form aggregates of many cells known as flocs.	tmpzr1t_l9r_go_relaxed.owl	flocculation via cell wall protein-carbohydrate interaction|coflocculation via lectin-mannose interaction|coflocculation|cell-cell adhesion involved in flocculation via cell wall protein-carbohydrate interaction|co-flocculation|flocculation via extracellular polymer|coflocculation via protein-carbohydrate interaction|cell-cell adhesion involved in flocculation	https://github.com/geneontology/go-ontology/issues/18785|https://github.com/geneontology/go-ontology/issues/20192			Wikipedia:Flocculation	The word floc derives from the Latin word floccus, which means a tuft of wool.		bf	2012-07-11T01:30:40Z			GO:0036282|GO:0000501|GO:0043690|GO:0036281|GO:0043689|GO:0032128		biological_process											owl:Class	
GO:0051587	biolink:NamedThing	inhibition of dopamine uptake involved in synaptic transmission	Any process that prevents the activation of the directed movement of dopamine into a cell.	tmpzr1t_l9r_go_relaxed.owl	inhibition of dopamine import involved in synaptic transmission													biological_process											owl:Class	
GO:0051609	biolink:NamedThing	inhibition of neurotransmitter uptake	Any process that prevents the activation of the directed movement of a neurotransmitter into a cell.	tmpzr1t_l9r_go_relaxed.owl	inhibition of neurotransmitter import													biological_process											owl:Class	
GO:0009392	biolink:NamedThing	N-acetyl-anhydromuramoyl-L-alanine amidase activity	Catalysis of the reaction: GlcNAc-1,6-anhMurNAc-L-Ala-gamma-D-Glu-DAP-D-Ala + H2O glcNAc-1,6-anhMurNAc + L-Ala-gamma-D-Glu-DAP-D-Ala.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN0-5225									molecular_function											owl:Class	
GO:0016810	biolink:NamedThing	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	Catalysis of the hydrolysis of any carbon-nitrogen bond, C-N, with the exception of peptide bonds.	tmpzr1t_l9r_go_relaxed.owl	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in other compounds				Reactome:R-HSA-6803753|EC:3.5.-.-									molecular_function											owl:Class	
GO:1905819	biolink:NamedThing	negative regulation of chromosome separation	Any process that stops, prevents or reduces the frequency, rate or extent of chromosome separation.	tmpzr1t_l9r_go_relaxed.owl	inhibition of chromosome separation|down regulation of chromosome separation|downregulation of rDNA separation|downregulation of chromosome separation|down-regulation of chromatid release|inhibition of chromatid release|downregulation of chromatid release|negative regulation of chromatid release|inhibition of rDNA separation|down regulation of rDNA separation|down-regulation of chromosome separation|negative regulation of rDNA separation|down regulation of chromatid release|down-regulation of rDNA separation							bhm	2017-01-13T13:55:27Z					biological_process											owl:Class	
GO:0038098	biolink:NamedThing	sequestering of BMP from receptor via BMP binding	Binding to a bone morphogenetic protein (BMP) in the extracellular region, and inhibiting BMP signaling by preventing BMP from binding to its cell surface receptor.	tmpzr1t_l9r_go_relaxed.owl	extracellular sequestering of BMP|extracellular sequestering of bone morphogenetic protein							bf	2012-02-22T11:28:54Z					biological_process											owl:Class	
GO:0035581	biolink:NamedThing	sequestering of extracellular ligand from receptor	The process of binding or confining an extracellular signaling ligand, such that the ligand is unable to bind to its cell surface receptor.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of protein bioavailability|extracellular sequestering of receptor ligand					Preventing a ligand from binding to its cell surface receptor be achieved by binding to the ligand directly, or by binding to members of a ligand-containing complex.		bf	2010-10-12T03:12:11Z					biological_process											owl:Class	
GO:0090123	biolink:NamedThing	lysosomal glycocalyx	The polysaccharide-based coating on the inner side of a lysosomal membrane. It may be involved in protecting the membrane from digestion by lysosomal enzymes.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/19782						tb	2009-12-07T01:16:20Z					cellular_component											owl:Class	
GO:0030112	biolink:NamedThing	glycocalyx	A carbohydrate rich layer at the outermost periphery of a cell.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Glycocalyx									cellular_component											owl:Class	
GO:1904221	biolink:NamedThing	negative regulation of serine C-palmitoyltransferase activity	Any process that stops, prevents or reduces the frequency, rate or extent of serine C-palmitoyltransferase activity.	tmpzr1t_l9r_go_relaxed.owl	down regulation of SPT|negative regulation of acyl-CoA:serine C-2 acyltransferase decarboxylating|negative regulation of SPT|inhibition of SPT|downregulation of SPT|downregulation of palmitoyl-CoA:L-serine C-palmitoyltransferase (decarboxylating) activity|inhibition of palmitoyl-CoA:L-serine C-palmitoyltransferase (decarboxylating) activity|down-regulation of 3-oxosphinganine synthetase activity|down regulation of acyl-CoA:serine C-2 acyltransferase decarboxylating|down-regulation of palmitoyl-CoA:L-serine C-palmitoyltransferase (decarboxylating) activity|down-regulation of SPT|down regulation of palmitoyl-CoA:L-serine C-palmitoyltransferase (decarboxylating) activity|downregulation of acyl-CoA:serine C-2 acyltransferase decarboxylating|down-regulation of acyl-CoA:serine C-2 acyltransferase decarboxylating|negative regulation of 3-oxosphinganine synthetase activity|inhibition of 3-oxosphinganine synthetase activity|downregulation of 3-oxosphinganine synthetase activity|inhibition of serine C-palmitoyltransferase activity|down-regulation of serine C-palmitoyltransferase activity|down regulation of serine C-palmitoyltransferase activity|downregulation of serine C-palmitoyltransferase activity|down regulation of 3-oxosphinganine synthetase activity|inhibition of acyl-CoA:serine C-2 acyltransferase decarboxylating|negative regulation of palmitoyl-CoA:L-serine C-palmitoyltransferase (decarboxylating) activity					Serinc proteins form a complex with serine and sphingolipid biosynthesis enzymes and regulates their activity through regulation of the substrate availability		rl	2015-05-15T08:27:39Z					biological_process											owl:Class	
GO:1904220	biolink:NamedThing	regulation of serine C-palmitoyltransferase activity	Any process that modulates the frequency, rate or extent of serine C-palmitoyltransferase activity.	tmpzr1t_l9r_go_relaxed.owl	regulation of SPT|regulation of 3-oxosphinganine synthetase activity|regulation of palmitoyl-CoA:L-serine C-palmitoyltransferase (decarboxylating) activity|regulation of acyl-CoA:serine C-2 acyltransferase decarboxylating|regulation of serine palmitoyltransferase					Serinc proteins form a complex with serine and sphingolipid biosynthesis enzymes and regulates their activity through regulation of the substrate availability		rl	2015-05-15T08:27:33Z					biological_process											owl:Class	
GO:0010873	biolink:NamedThing	positive regulation of cholesterol esterification	Any process that increases the frequency, rate or extent of cholesterol esterification. Cholesterol esterification is the lipid modification process in which a sterol ester is formed by the combination of a carboxylic acid (often a fatty acid) and cholesterol. In the blood this process is associated with the conversion of free cholesterol into cholesteryl ester, which is then sequestered into the core of a lipoprotein particle.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0045940	biolink:NamedThing	positive regulation of steroid metabolic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving steroids.	tmpzr1t_l9r_go_relaxed.owl	stimulation of steroid metabolic process|up-regulation of steroid metabolic process|upregulation of steroid metabolic process|positive regulation of steroid metabolism|activation of steroid metabolic process|up regulation of steroid metabolic process													biological_process											owl:Class	
GO:0044683	biolink:NamedThing	methylthiol:coenzyme M methyltransferase activity	Catalysis of the overall reaction: methyl-Co(III) methylated-thiol-specific corrinoid protein + coenzyme M = Co(I) methylated--thiol-specific corrinoid protein + methyl-CoM.	tmpzr1t_l9r_go_relaxed.owl	methylthiol:coenzyme M methyl transferase activity				EC:2.1.1.251|MetaCyc:RXN-8125|RHEA:32667	This reaction is achieved by the catalysis of two successive steps carried out by the same enzyme - the transfer of a methyl group from the substrate to the cobalt cofactor of a methylated-thiol-specific corrinoid protein (MtsB), and the subsequent transfer of the methyl group from the corrinoid protein to coenzyme M. With most other methanogenesis substrates this process is carried out by two different enzymes (for example, EC:2.1.1.90, methanol-corrinoid protein Co-methyltransferase, and EC:2.1.1.246, methylated methanol-specific corrinoid protein:coenzyme M methyltransferase). The cobalt is oxidized during methylation from the Co(I) state to the Co(III) state, and is reduced back to the Co(I) form during demethylation.		jl	2012-08-15T11:41:24Z					molecular_function											owl:Class	
GO:0072489	biolink:NamedThing	methylammonium transmembrane transport	The process in which methylammonium is transported across a membrane.	tmpzr1t_l9r_go_relaxed.owl	methylammonium membrane transport					Note that this term is not intended for use in annotating lateral movement within membranes.		mah	2010-12-10T10:36:33Z					biological_process											owl:Class	
GO:0015843	biolink:NamedThing	methylammonium transport	The directed movement of methylammonium into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0002725	biolink:NamedThing	negative regulation of T cell cytokine production	Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell cytokine production.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of T lymphocyte cytokine production|downregulation of T cell cytokine production|down-regulation of T cell cytokine production|down regulation of T cell cytokine production|inhibition of T cell cytokine production|negative regulation of T-lymphocyte cytokine production|negative regulation of T-cell cytokine production													biological_process											owl:Class	
GO:1990587	biolink:NamedThing	FtsQBL complex	A protein complex required for prokaryotic cell division (FtsZ-dependent cytokinesis). Part of the divisome. Assembled independently of the other divisome components in the cytoplasm prior to transport to the cell septum. In E. coli consists of FtsB, FtsL and FtsQ.	tmpzr1t_l9r_go_relaxed.owl	FtsB-FtsL-FtsQ complex					An example of this is FtsB in E. coli (P0A6S5) in PMID:15165235 (inferred from physical interaction).		bhm	2014-12-15T09:25:09Z					cellular_component											owl:Class	
GO:1990586	biolink:NamedThing	divisome complex	A protein complex required for prokaryotic cell division (FtsZ-dependent cytokinesis). These complexes are assembled and recruited to the cell septum in a strictly controlled sequence and co-ordinate invagination of the cell membrane, inward growth of the peptidoglycan layer, constriction of the outer membrane and separation of daughter cells.	tmpzr1t_l9r_go_relaxed.owl								bhm	2014-12-15T09:13:38Z					cellular_component											owl:Class	
GO:0016815	biolink:NamedThing	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in nitriles	Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a nitrile, a compound containing the cyano radical, -CN.	tmpzr1t_l9r_go_relaxed.owl					EC:3.5.5.-									molecular_function											owl:Class	
GO:0032899	biolink:NamedThing	regulation of neurotrophin production	Any process that modulates the frequency, rate, or extent of production of a neurotrophin.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0106398	biolink:NamedThing	negative regulation of R7 cell fate commitment	Any process that stops, prevents or reduces the frequency, rate or extent of R7 cell fate commitment.	tmpzr1t_l9r_go_relaxed.owl								hjd	2021-10-08T19:14:54Z					biological_process											owl:Class	
GO:0106396	biolink:NamedThing	regulation of R7 cell fate commitment	Any process that modulates the frequency, rate or extent of R7 cell fate commitment.	tmpzr1t_l9r_go_relaxed.owl								hjd	2021-10-08T19:14:13Z					biological_process											owl:Class	
GO:1903635	biolink:NamedThing	positive regulation of leucine-tRNA ligase activity	Any process that activates or increases the frequency, rate or extent of leucine-tRNA ligase activity.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of leucyl-transfer ribonucleic acid synthetase activity|upregulation of leucine-tRNA synthetase activity|upregulation of L-leucine:tRNALeu ligase (AMP-forming)|up-regulation of leucyl-transfer RNA synthetase activity|activation of L-leucine:tRNALeu ligase (AMP-forming)|positive regulation of leucyl-transfer ribonucleate synthetase activity|positive regulation of leucyl-transfer RNA synthetase activity|activation of leucine-tRNA ligase activity|up-regulation of leucine-tRNA synthetase activity|positive regulation of leucine translase activity|activation of leucyl-transfer ribonucleate synthetase activity|positive regulation of leucyl-transfer ribonucleic acid synthetase activity|positive regulation of leucine-tRNA synthetase activity|upregulation of leucyl-transfer ribonucleate synthetase activity|positive regulation of L-leucine:tRNALeu ligase (AMP-forming)|activation of leucine translase activity|up-regulation of leucine-tRNA ligase activity|activation of leucine-tRNA synthetase activity|up-regulation of L-leucine:tRNALeu ligase (AMP-forming)|up regulation of leucyl-transfer ribonucleate synthetase activity|activation of leucyl-tRNA synthetase activity|upregulation of leucyl-transfer RNA synthetase activity|up regulation of leucine translase activity|up-regulation of leucyl-tRNA synthetase activity|upregulation of leucyl-transfer ribonucleic acid synthetase activity|up regulation of leucyl-transfer ribonucleic acid synthetase activity|up-regulation of leucine translase activity|upregulation of leucyl-tRNA synthetase activity|up regulation of leucine-tRNA ligase activity|upregulation of leucine-tRNA ligase activity|up-regulation of leucyl-transfer ribonucleate synthetase activity|up regulation of leucyl-transfer RNA synthetase activity|activation of leucyl-transfer RNA synthetase activity|up regulation of L-leucine:tRNALeu ligase (AMP-forming)|upregulation of leucine translase activity|up regulation of leucyl-tRNA synthetase activity|activation of leucyl-transfer ribonucleic acid synthetase activity|up regulation of leucine-tRNA synthetase activity|positive regulation of leucyl-tRNA synthetase activity							sl	2014-11-20T00:25:08Z					biological_process											owl:Class	
GO:0150072	biolink:NamedThing	positive regulation of arginase activity	Any process that activates or increases the frequency, rate or extent of arginase activity.	tmpzr1t_l9r_go_relaxed.owl								bc	2018-07-25T09:26:20Z					biological_process											owl:Class	
GO:0005771	biolink:NamedThing	multivesicular body	A type of endosome in which regions of the limiting endosomal membrane invaginate to form internal vesicles; membrane proteins that enter the internal vesicles are sequestered from the cytoplasm.	tmpzr1t_l9r_go_relaxed.owl	MVE|multivesicular endosome|MVB				NIF_Subcellular:sao2045955158									cellular_component											owl:Class	
GO:0005770	biolink:NamedThing	late endosome	A prelysosomal endocytic organelle differentiated from early endosomes by lower lumenal pH and different protein composition. Late endosomes are more spherical than early endosomes and are mostly juxtanuclear, being concentrated near the microtubule organizing center.	tmpzr1t_l9r_go_relaxed.owl	PVC|prevacuolar compartment				NIF_Subcellular:nlx_subcell_20090702									cellular_component											owl:Class	
GO:0046672	biolink:NamedThing	positive regulation of compound eye retinal cell programmed cell death	Any process that activates or increases the frequency, rate or extent of programmed cell death that occurs in the compound eye retina.	tmpzr1t_l9r_go_relaxed.owl	activation of retinal cell programmed cell death|up-regulation of retinal cell programmed cell death|positive regulation of retinal cell programmed cell death|up regulation of retinal cell programmed cell death|stimulation of retinal cell programmed cell death|upregulation of retinal cell programmed cell death													biological_process											owl:Class	
GO:0046670	biolink:NamedThing	positive regulation of retinal cell programmed cell death	Any process that activates or increases the frequency, rate or extent of programmed cell death that occurs in the retina.	tmpzr1t_l9r_go_relaxed.owl	upregulation of retinal programmed cell death|positive regulation of retinal programmed cell death|up regulation of retinal programmed cell death|up-regulation of retinal programmed cell death|activation of retinal programmed cell death|stimulation of retinal programmed cell death													biological_process											owl:Class	
GO:0046823	biolink:NamedThing	negative regulation of nucleocytoplasmic transport	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of substances between the cytoplasm and the nucleus.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of nucleocytoplasmic transport|downregulation of nucleocytoplasmic transport|inhibition of nucleocytoplasmic transport|down regulation of nucleocytoplasmic transport													biological_process											owl:Class	
GO:0032387	biolink:NamedThing	negative regulation of intracellular transport	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of substances within cells.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of intracellular transport|down regulation of intracellular transport|downregulation of intracellular transport|inhibition of intracellular transport													biological_process											owl:Class	
GO:1903432	biolink:NamedThing	regulation of TORC1 signaling	Any process that modulates the frequency, rate or extent of TORC1 signaling.	tmpzr1t_l9r_go_relaxed.owl	regulation of TORC1 signal transduction							jl	2014-09-15T13:35:39Z					biological_process											owl:Class	
GO:0032006	biolink:NamedThing	regulation of TOR signaling	Any process that modulates the frequency, rate or extent of TOR signaling.	tmpzr1t_l9r_go_relaxed.owl	regulation of TOR signaling pathway|regulation of target of rapamycin signaling pathway|regulation of target of rapamycin signalling pathway|regulation of TOR signalling pathway|regulation of TOR signaling cascade													biological_process											owl:Class	
GO:0010904	biolink:NamedThing	regulation of UDP-glucose catabolic process	Any process that modulates the rate, frequency or extent of UDP-glucose catabolism. UDP-glucose catabolic processes are the chemical reactions and pathways resulting in the breakdown of UDP-glucose, uridinediphosphoglucose, a substance composed of glucose in glycosidic linkage with uridine diphosphate.	tmpzr1t_l9r_go_relaxed.owl	regulation of UDP-glucose catabolism													biological_process											owl:Class	
GO:0019800	biolink:NamedThing	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan	The formation of a cross-link between peptide chains mediated by a chondroitin 4-sulfate glycosaminoglycan that originates from a typical O-glycosidic link to serine of one chain; the other chain is esterified, via the alpha-carbon of its C-terminal Asp, to C-6 of an internal N-acetylgalactosamine of the glycosaminoglycan chain.	tmpzr1t_l9r_go_relaxed.owl	peptide cross-linking via chondroitin 4-sulphate glycosaminoglycan				RESID:AA0219									biological_process											owl:Class	
GO:0018209	biolink:NamedThing	peptidyl-serine modification	The modification of peptidyl-serine.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0000277	biolink:NamedThing	[cytochrome c]-lysine N-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + cytochrome c L-lysine = S-adenosyl-L-homocysteine + cytochrome c N6-methyl-L-lysine. This is the addition of a methyl group to the N6 atom of a lysine residue in cytochrome c.	tmpzr1t_l9r_go_relaxed.owl	S-adenosyl-L-methionine:cytochrome c-L-lysine 6-N-methyltransferase activity|S-adenosyl-L-methionine:cytochrome c-L-lysine N6-methyltransferase activity|cytochrome c-specific protein-lysine methyltransferase activity|cytochrome c (lysine) methyltransferase activity|cytochrome c-lysine N-methyltransferase activity|cytochrome c methyltransferase activity|cytochrome c-specific protein methylase III activity				RHEA:24312|EC:2.1.1.59|MetaCyc:2.1.1.59-RXN									molecular_function											owl:Class	
GO:0016279	biolink:NamedThing	protein-lysine N-methyltransferase activity	Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to the epsilon-amino group of a lysine residue in a protein substrate.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-8932276|Reactome:R-HSA-8932243|Reactome:R-HSA-8931858|Reactome:R-HSA-8865237|Reactome:R-HSA-8932275|Reactome:R-HSA-8932413|Reactome:R-HSA-8931974|Reactome:R-HSA-212263|Reactome:R-HSA-8932221									molecular_function											owl:Class	
GO:0046060	biolink:NamedThing	dATP metabolic process	The chemical reactions and pathways involving dATP, deoxyadenosine triphosphate (2'-deoxyadenosine 5'-triphosphate).	tmpzr1t_l9r_go_relaxed.owl	dATP metabolism													biological_process											owl:Class	
GO:0009151	biolink:NamedThing	purine deoxyribonucleotide metabolic process	The chemical reactions and pathways involving purine deoxyribonucleotide, a compound consisting of deoxyribonucleoside (a purine base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.	tmpzr1t_l9r_go_relaxed.owl	purine deoxyribonucleotide metabolism													biological_process											owl:Class	
GO:1900840	biolink:NamedThing	regulation of helvolic acid biosynthetic process	Any process that modulates the frequency, rate or extent of helvolic acid biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl								di	2012-06-07T09:38:33Z					biological_process											owl:Class	
GO:1901381	biolink:NamedThing	positive regulation of potassium ion transmembrane transport	Any process that activates or increases the frequency, rate or extent of potassium ion transmembrane transport.	tmpzr1t_l9r_go_relaxed.owl	activation of potassium ion transmembrane transport|upregulation of potassium ion transmembrane transport|up-regulation of potassium ion transmembrane transport|positive regulation of potassium ion membrane transport|up regulation of potassium ion transmembrane transport							rl	2012-09-28T15:59:25Z					biological_process											owl:Class	
GO:0043268	biolink:NamedThing	positive regulation of potassium ion transport	Any process that activates or increases the frequency, rate or extent of the directed movement of potassium ions (K+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	upregulation of potassium ion transport|up-regulation of potassium ion transport|positive regulation of potassium transport|positive regulation of K+ transport|activation of potassium ion transport|positive regulation of potassium ion conductance|up regulation of potassium ion transport|positive regulation of K+ conductance|positive regulation of potassium conductance|stimulation of potassium ion transport													biological_process											owl:Class	
GO:2001097	biolink:NamedThing	laminaritriose transport	The directed movement of a laminaritrioseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl								jl	2011-09-21T02:11:36Z					biological_process											owl:Class	
GO:2001088	biolink:NamedThing	trisaccharide transport	The directed movement of a trisaccharideacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl								jl	2011-09-21T12:59:46Z					biological_process											owl:Class	
GO:1901748	biolink:NamedThing	leukotriene D4 metabolic process	The chemical reactions and pathways involving leukotriene D4.	tmpzr1t_l9r_go_relaxed.owl	leukotriene D4 metabolism							yaf	2013-01-14T10:56:12Z					biological_process											owl:Class	
GO:0032437	biolink:NamedThing	cuticular plate	A dense network of actin filaments found beneath the apical cell surface of hair cells, and into which stereocilia are inserted.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0032539	biolink:NamedThing	negative regulation of host-seeking behavior	Any process that stops, prevents, or reduces the frequency, rate or extent of any behavior associated with finding a host organism.	tmpzr1t_l9r_go_relaxed.owl	inhibition of host-seeking behavior|down regulation of host-seeking behavior|negative regulation of host-seeking behaviour|downregulation of host-seeking behavior|down-regulation of host-seeking behavior													biological_process											owl:Class	
GO:0032538	biolink:NamedThing	regulation of host-seeking behavior	Any process that modulates the frequency, rate or extent of any behavior associated with finding a host organism.	tmpzr1t_l9r_go_relaxed.owl	regulation of host-seeking behaviour													biological_process											owl:Class	
GO:0050666	biolink:NamedThing	regulation of homocysteine metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving homocysteine, the amino acid alpha-amino-gamma-mercaptobutanoic acid.	tmpzr1t_l9r_go_relaxed.owl	regulation of homocysteine metabolism|regulation of Hcy metabolic process|regulation of Hcy metabolism													biological_process											owl:Class	
GO:0045710	biolink:NamedThing	negative regulation of larval salivary gland boundary specification	Any process that stops, prevents, or reduces the frequency, rate or extent of salivary gland determination in a larval organism.	tmpzr1t_l9r_go_relaxed.owl	downregulation of larval salivary gland determination|down regulation of larval salivary gland determination|negative regulation of larval salivary gland determination|inhibition of larval salivary gland determination|down-regulation of larval salivary gland determination													biological_process											owl:Class	
GO:0051149	biolink:NamedThing	positive regulation of muscle cell differentiation	Any process that activates or increases the frequency, rate or extent of muscle cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	stimulation of muscle cell differentiation|upregulation of muscle cell differentiation|up regulation of muscle cell differentiation|activation of muscle cell differentiation|up-regulation of muscle cell differentiation													biological_process											owl:Class	
GO:0051147	biolink:NamedThing	regulation of muscle cell differentiation	Any process that modulates the frequency, rate or extent of muscle cell differentiation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0019713	biolink:NamedThing	peptidyl-L-glutamic acid 5-methyl ester biosynthetic process from glutamine	The coupled methyl esterification and deamidation of peptidyl-glutamine.	tmpzr1t_l9r_go_relaxed.owl	peptidyl-L-glutamic acid 5-methyl ester anabolism from glutamine|peptidyl-L-glutamic acid 5-methyl ester synthesis from glutamine|peptidyl-L-glutamic acid 5-methyl ester formation from glutamine				RESID:AA0072									biological_process											owl:Class	
GO:0018390	biolink:NamedThing	peptidyl-L-glutamic acid 5-methyl ester biosynthetic process from peptidyl-glutamic acid or peptidyl-glutamine	The methyl esterification of peptidyl-glutamic acid or peptidyl-glutamine to form the derivative glutamic acid 5-methyl ester.	tmpzr1t_l9r_go_relaxed.owl	peptidyl-L-glutamic acid 5-methyl ester synthesis from peptidyl-glutamic acid or peptidyl-glutamine|peptidyl-L-glutamic acid 5-methyl ester formation from peptidyl-glutamic acid or peptidyl-glutamine|peptidyl-L-glutamic acid 5-methyl ester anabolism from peptidyl-glutamic acid or peptidyl-glutamine				RESID:AA0072									biological_process											owl:Class	
GO:0034617	biolink:NamedThing	tetrahydrobiopterin binding	Binding to a tetrahydrobiopterin, 5,6,7,8-tetrahydrobiopterin or a derivative thereof; tetrahydrobiopterins are enzyme cofactors that carry electrons in redox reactions.	tmpzr1t_l9r_go_relaxed.owl	H4biopterin binding|BH4 binding|sapropterin binding													molecular_function											owl:Class	
GO:0019290	biolink:NamedThing	siderophore biosynthetic process	The chemical reactions and pathways resulting in the formation of siderophores, low molecular weight Fe(III)-chelating substances made by aerobic or facultatively anaerobic bacteria, especially when growing under iron deficient conditions. The complexes of Fe(3+)-siderophores have very high stability constants and are taken up by specific transport systems by microorganisms; the subsequent release of iron requires enzymatic action.	tmpzr1t_l9r_go_relaxed.owl	siderophore synthesis|siderophore biosynthesis|siderophore anabolism|siderophore biosynthetic process, peptide modification|siderochrome biosynthetic process|siderophore formation|siderochrome biosynthesis|siderophore biosynthetic process, peptide formation											GO:0031180|GO:0031178		biological_process											owl:Class	
GO:1902970	biolink:NamedThing	premeiotic DNA replication DNA duplex unwinding	Any DNA duplex unwinding involved in meiotic cell cycle DNA replication.	tmpzr1t_l9r_go_relaxed.owl	DNA duplex unwinding involved in meiotic DNA replication|DNA duplex unwinding involved in meiotic cell cycle DNA replication							jl	2014-05-06T15:20:41Z					biological_process											owl:Class	
GO:0070192	biolink:NamedThing	chromosome organization involved in meiotic cell cycle	A process of chromosome organization that is involved in a meiotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl	meiotic chromosome organization|chromosome organisation involved in meiosis													biological_process											owl:Class	
GO:0015081	biolink:NamedThing	sodium ion transmembrane transporter activity	Enables the transfer of sodium ions (Na+) from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	sodium transporter activity											GO:0022816		molecular_function											owl:Class	
GO:0071781	biolink:NamedThing	endoplasmic reticulum cisternal network	A subcompartment of the endoplasmic reticulum consisting of flattened, disc-shaped domains known as cisternae.  These are typically found close to the nucleus and are generally more prominent in secretory cells.	tmpzr1t_l9r_go_relaxed.owl	ER cisternal network							mah	2010-09-01T01:29:54Z					cellular_component											owl:Class	
GO:0098827	biolink:NamedThing	endoplasmic reticulum subcompartment	A distinct region of the endoplasmic reticulum.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0034787	biolink:NamedThing	1-hydro-1,1a-dihydroxy-9-fluorenone dehydrogenase activity	Catalysis of the reaction: 1-hydro-1,1a-dihydroxy-9-fluorenone + H2O = 2,3-dihydroxy-2'-carboxybiphenyl + 3 H+ + 2 e-.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r1040									molecular_function											owl:Class	
GO:0046464	biolink:NamedThing	acylglycerol catabolic process	The chemical reactions and pathways resulting in the breakdown of acylglycerol, any mono-, di- or triester of glycerol with (one or more) fatty acids.	tmpzr1t_l9r_go_relaxed.owl	acylglycerol degradation|acylglycerol breakdown|acylglycerol catabolism													biological_process											owl:Class	
GO:0046461	biolink:NamedThing	neutral lipid catabolic process	The chemical reactions and pathways resulting in the breakdown of neutral lipids, lipids only soluble in solvents of very low polarity.	tmpzr1t_l9r_go_relaxed.owl	neutral lipid degradation|neutral lipid catabolism|neutral lipid breakdown													biological_process											owl:Class	
GO:1901757	biolink:NamedThing	butirosin catabolic process	The chemical reactions and pathways resulting in the breakdown of butirosin.	tmpzr1t_l9r_go_relaxed.owl	butirosin catabolism|butirosin degradation|butirosin breakdown							yaf	2013-01-14T11:36:22Z					biological_process											owl:Class	
GO:0016139	biolink:NamedThing	glycoside catabolic process	The chemical reactions and pathways resulting in the breakdown of glycosides, compounds in which a glycosyl group is substituted into a hydroxyl, thiol or selenol group in another compound.	tmpzr1t_l9r_go_relaxed.owl	glycoside breakdown|glycoside degradation|O-glycoside catabolism|O-glycoside breakdown|glycoside catabolism|O-glycoside degradation|O-glycoside catabolic process											GO:0016142		biological_process											owl:Class	
GO:1904671	biolink:NamedThing	negative regulation of cell differentiation involved in stem cell population maintenance	Any negative regulation of cell differentiation that is involved in stem cell population maintenance.	tmpzr1t_l9r_go_relaxed.owl	downregulation of cell differentiation involved in maintenance of pluripotency|downregulation of cell differentiation involved in stem cell population maintenance|down regulation of cell differentiation involved in maintenance of pluripotency|down-regulation of cell differentiation involved in stem cell population maintenance|down-regulation of cell differentiation involved in maintenance of pluripotency|inhibition of cell differentiation involved in stem cell population maintenance|inhibition of cell differentiation involved in maintenance of pluripotency|negative regulation of cell differentiation involved in maintenance of pluripotency|down regulation of cell differentiation involved in stem cell population maintenance							tb	2015-09-12T00:46:08Z					biological_process											owl:Class	
GO:0045596	biolink:NamedThing	negative regulation of cell differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	inhibition of cell differentiation|down-regulation of cell differentiation|downregulation of cell differentiation|down regulation of cell differentiation													biological_process											owl:Class	
GO:0071468	biolink:NamedThing	cellular response to acidic pH	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus with pH < 7. pH is a measure of the acidity or basicity of an aqueous solution.	tmpzr1t_l9r_go_relaxed.owl	cellular response to acidity					This term should be used to annotate instances where a cell is responding to a chemical that is playing the role of an acid (e.g. proton donor) and therefore lowering the pH. If instead you wish to describe a response to a specific acid as a chemical, such as the anion portion of glutamate, please annotate to the appropriate child of GO:0071229 'cellular response to acid chemical'.		mah	2009-12-18T11:42:35Z					biological_process											owl:Class	
GO:0010447	biolink:NamedThing	response to acidic pH	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus with pH < 7. pH is a measure of the acidity or basicity of an aqueous solution.	tmpzr1t_l9r_go_relaxed.owl	response to acidity					This term should be used to annotate instances where a cell or organism is responding to a chemical that is playing the role of an acid (e.g. proton donor) and therefore lowering the pH. If instead you wish to describe a response to a specific acid as a chemical, such as the anion portion of glutamate, please annotate to the appropriate child of GO:0001101 'response to acid chemical'.								biological_process											owl:Class	
GO:0001642	biolink:NamedThing	group III metabotropic glutamate receptor activity	A G protein-coupled receptor that is activated by L-AP-4 and inhibits adenylate cyclase activity.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0001640	biolink:NamedThing	adenylate cyclase inhibiting G protein-coupled glutamate receptor activity	Combining with glutamate and transmitting the signal across the membrane by activating the alpha-subunit of an associated heterotrimeric G-protein complex to inhibit downstream adenylate cyclase activity.	tmpzr1t_l9r_go_relaxed.owl	adenylyl cyclase inhibiting metabotropic glutamate receptor activity|adenylate cyclase inhibiting metabotropic glutamate receptor activity													molecular_function											owl:Class	
GO:1903540	biolink:NamedThing	establishment of protein localization to postsynaptic membrane	The directed movement of a protein to a specific location in a postsynaptic membrane.	tmpzr1t_l9r_go_relaxed.owl	establishment of protein localisation in postsynaptic membrane|establishment of protein localisation to postsynaptic membrane|establishment of protein localization in postsynaptic membrane							kmv	2014-10-10T11:24:03Z					biological_process											owl:Class	
GO:0090150	biolink:NamedThing	establishment of protein localization to membrane	The directed movement of a protein to a specific location in a membrane.	tmpzr1t_l9r_go_relaxed.owl	establishment of protein localization in membrane|establishment of protein localisation in membrane							tb	2009-12-08T03:18:51Z					biological_process											owl:Class	
GO:1905057	biolink:NamedThing	voltage-gated calcium channel activity involved in regulation of postsynaptic cytosolic calcium levels	Any voltage-gated calcium channel activity that is involved in regulation of postsynaptic cytosolic calcium ion concentration.	tmpzr1t_l9r_go_relaxed.owl	voltage-gated calcium ion channel activity involved in regulation of postsynaptic cytosolic calcium ion concentration|depolarization-activated voltage-gated calcium channel involved in regulation of postsynaptic cytosolic calcium ion concentration|voltage gated calcium channel activity involved in regulation of postsynaptic cytosolic calcium ion concentration|depolarization-activated voltage gated calcium channel activity involved in regulation of postsynaptic cytosolic calcium ion concentration|voltage-dependent calcium channel activity involved in regulation of postsynaptic cytosolic calcium ion concentration|voltage-gated calcium channel activity involved in regulation of postsynaptic cytosolic calcium levels|dihydropyridine-sensitive calcium channel activity involved in regulation of postsynaptic cytosolic calcium ion concentration|voltage-sensitive calcium channel involved in regulation of postsynaptic cytosolic calcium ion concentration|depolarization-activated voltage-gated calcium channel activity involved in regulation of postsynaptic cytosolic calcium ion concentration							dos	2016-03-18T12:31:48Z					molecular_function											owl:Class	
GO:0099511	biolink:NamedThing	voltage-gated calcium channel activity involved in regulation of cytosolic calcium levels	Regulation of cytosolic calcium ion concentrations via the directed movement of calcium ions across the plasma-membrane into the cytosol via the action of a voltage-gated calcium ion channel.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0018611	biolink:NamedThing	toluate dioxygenase activity	Catalysis of the reaction: methylbenzoate + NADH + O2 + H+ = NAD+ + 1,2-dihydroxymethylcyclohexa-3,5-dienecarboxylate.	tmpzr1t_l9r_go_relaxed.owl					EC:1.14.12.-|UM-BBD_enzymeID:e0190									molecular_function											owl:Class	
GO:0016651	biolink:NamedThing	oxidoreductase activity, acting on NAD(P)H	Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.	tmpzr1t_l9r_go_relaxed.owl	NAD(P)H dehydrogenase|oxidoreductase activity, acting on NADH or NADPH|oxidoreductase activity, acting on NADH or NADPH, other acceptor				EC:1.6.-.-|Reactome:R-HSA-8956458|Reactome:R-HSA-109343									molecular_function											owl:Class	
GO:0051744	biolink:NamedThing	3,8-divinyl protochlorophyllide a 8-vinyl reductase activity	Catalysis of the reaction: divinyl protochlorophyllide a + NADPH + H+ = monovinyl protochlorophyllide a + NADP+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN1F-72|RHEA:48884									molecular_function											owl:Class	
GO:0061157	biolink:NamedThing	mRNA destabilization	Any process that decreases the stability of an mRNA molecule, making it more vulnerable to degradative processes. Messenger RNA is the intermediate molecule between DNA and protein. It includes UTR and coding sequences. It does not contain introns.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-06-22T08:42:10Z					biological_process											owl:Class	
GO:0098808	biolink:NamedThing	mRNA cap binding	Binding to a 7-methylguanosine (m7G) group or derivative located at the 5' end of an mRNA molecule.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1905956	biolink:NamedThing	positive regulation of endothelial tube morphogenesis	Any process that activates or increases the frequency, rate or extent of endothelial tube morphogenesis.	tmpzr1t_l9r_go_relaxed.owl	up regulation of endothelial tube morphogenesis|activation of endothelial tube morphogenesis|upregulation of endothelial tube morphogenesis|up-regulation of endothelial tube morphogenesis							rph	2017-02-21T15:17:39Z					biological_process											owl:Class	
GO:0061914	biolink:NamedThing	negative regulation of growth plate cartilage chondrocyte proliferation	Any process that decreases the rate, frequency, or extent of the multiplication or reproduction of chondrocytes in a growing endochondral bone, resulting in the expansion of a cell population.	tmpzr1t_l9r_go_relaxed.owl								dph	2017-07-10T17:39:17Z					biological_process											owl:Class	
GO:0008285	biolink:NamedThing	negative regulation of cell population proliferation	Any process that stops, prevents or reduces the rate or extent of cell proliferation.	tmpzr1t_l9r_go_relaxed.owl	downregulation of cell proliferation|inhibition of cell proliferation|negative regulation of cell proliferation|down-regulation of cell proliferation|down regulation of cell proliferation													biological_process											owl:Class	
GO:0090730	biolink:NamedThing	Las1 complex	A four subunit complex, that comprises all the necessary RNA processing enzymes (endonuclease, polynucleotide kinase, and exonuclease) to mediate 'cistronic rRNA transcript ITS2 (internal transcribed spacer) cleavage' (GO:0000448).	tmpzr1t_l9r_go_relaxed.owl	Las1-Grc3-Rat1-Rai1							tb	2017-01-05T16:51:46Z					cellular_component											owl:Class	
GO:1905354	biolink:NamedThing	exoribonuclease complex	A protein complex which is capable of exoribonuclease activity.	tmpzr1t_l9r_go_relaxed.owl						An example of this is DIS3 in human (Q9Y2L1) in PMID:17174896 (inferred from direct assay).		bhm	2016-08-08T10:18:29Z					cellular_component											owl:Class	
GO:0008887	biolink:NamedThing	glycerate kinase activity	Catalysis of the reaction: D-glycerate + ATP = 3-phospho-D-glycerate + ADP + 2 H(+).	tmpzr1t_l9r_go_relaxed.owl	D-glyceric acid kinase activity|ATP:D-glycerate 2-phosphotransferase activity|ATP:(R)-glycerate 3-phosphotransferase activity|D-glycerate 3-kinase activity|GK|D-glycerate kinase activity|glycerate-3-kinase activity|glycerate kinase (phosphorylating)				KEGG_REACTION:R01514|RHEA:23516|EC:2.7.1.31|Reactome:R-HSA-6799495|MetaCyc:GLY3KIN-RXN									molecular_function											owl:Class	
GO:1904119	biolink:NamedThing	negative regulation of otic vesicle morphogenesis	Any process that stops, prevents or reduces the frequency, rate or extent of otic vesicle morphogenesis.	tmpzr1t_l9r_go_relaxed.owl	down regulation of otic vesicle morphogenesis|downregulation of otic vesicle morphogenesis|inhibition of otic vesicle morphogenesis|down-regulation of otic vesicle morphogenesis							pga	2015-04-07T14:01:02Z					biological_process											owl:Class	
GO:0042207	biolink:NamedThing	styrene catabolic process	The chemical reactions and pathways resulting in the breakdown of styrene, an aromatic hydrocarbon liquid used in the manufacture of polystyrene.	tmpzr1t_l9r_go_relaxed.owl	styrene breakdown|styrene catabolism|styrene degradation				UM-BBD_pathwayID:sty									biological_process											owl:Class	
GO:0019439	biolink:NamedThing	aromatic compound catabolic process	The chemical reactions and pathways resulting in the breakdown of aromatic compounds, any substance containing an aromatic carbon ring.	tmpzr1t_l9r_go_relaxed.owl	aromatic compound breakdown|aromatic hydrocarbon catabolic process|aromatic compound catabolism|aromatic compound degradation|aromatic hydrocarbon catabolism													biological_process											owl:Class	
GO:0032214	biolink:NamedThing	negative regulation of telomere maintenance via semi-conservative replication	Any process that stops, prevents, or reduces the frequency, rate or extent of the semi-conservative replication of telomeric DNA.	tmpzr1t_l9r_go_relaxed.owl	down regulation of telomere maintenance via semi-conservative replication|inhibition of telomere maintenance via semi-conservative replication|downregulation of telomere maintenance via semi-conservative replication|down-regulation of telomere maintenance via semi-conservative replication													biological_process											owl:Class	
GO:0032213	biolink:NamedThing	regulation of telomere maintenance via semi-conservative replication	Any process that modulates the frequency, rate or extent of the semi-conservative replication of telomeric DNA.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0009103	biolink:NamedThing	lipopolysaccharide biosynthetic process	The chemical reactions and pathways resulting in the formation of lipopolysaccharides, any of a group of related, structurally complex components of the outer membrane of Gram-negative bacteria.	tmpzr1t_l9r_go_relaxed.owl	lipopolysaccharide biosynthesis|LPS biosynthetic process|lipopolysaccharide anabolism|lipopolysaccharide formation|lipopolysaccharide synthesis				KEGG_PATHWAY:map00540									biological_process											owl:Class	
GO:0008653	biolink:NamedThing	lipopolysaccharide metabolic process	The chemical reactions and pathways involving lipopolysaccharides, a group of related, structurally complex components of the outer membrane of Gram-negative bacteria. Lipopolysaccharides consist three covalently linked regions, lipid A, core oligosaccharide, and an O side chain. Lipid A is responsible for the toxicity of the lipopolysaccharide.	tmpzr1t_l9r_go_relaxed.owl	lipopolysaccharide metabolism|LPS metabolic process													biological_process											owl:Class	
GO:0036406	biolink:NamedThing	anchored component of periplasmic side of cell outer membrane	The component of the cell outer membrane consisting of gene products and protein complexes that are tethered to the periplasmic side of membrane by only a covalently attached anchor, embedded in the periplasmic side of the membrane only.	tmpzr1t_l9r_go_relaxed.owl	anchored to internal side of cell outer membrane|anchored to periplasmic side of cell outer membrane							bf	2013-08-15T11:45:39Z					cellular_component											owl:Class	
GO:0036405	biolink:NamedThing	anchored component of cell outer membrane	The component of the cell outer membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping.	tmpzr1t_l9r_go_relaxed.owl	anchored to cell outer membrane							bf	2013-08-15T11:40:41Z					cellular_component											owl:Class	
GO:0051940	biolink:NamedThing	regulation of catecholamine uptake involved in synaptic transmission	Any process that modulates the frequency, rate or extent of the directed movement of catecholamine neurotransmitters into a neuron or glial cell.	tmpzr1t_l9r_go_relaxed.owl	regulation of catecholamine neurotransmitter uptake|regulation of catecholamine neurotransmitter reuptake|regulation of catecholamine uptake during transmission of nerve impulse													biological_process											owl:Class	
GO:1905109	biolink:NamedThing	regulation of pulmonary blood vessel remodeling	Any process that modulates the frequency, rate or extent of pulmonary blood vessel remodeling.	tmpzr1t_l9r_go_relaxed.owl								bc	2016-04-06T13:07:24Z					biological_process											owl:Class	
GO:0060312	biolink:NamedThing	regulation of blood vessel remodeling	Any process that modulates the rate, frequency or extent of blood vessel remodeling, the reorganization or renovation of existing blood vessels.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0010520	biolink:NamedThing	regulation of reciprocal meiotic recombination	Any process that modulates the frequency, rate or extent of recombination during meiosis. Reciprocal meiotic recombination is the cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1900761	biolink:NamedThing	averantin metabolic process	The chemical reactions and pathways involving averantin.	tmpzr1t_l9r_go_relaxed.owl	averantin metabolism							di	2012-06-04T09:14:22Z					biological_process											owl:Class	
GO:0021999	biolink:NamedThing	neural plate anterior/posterior regionalization	The process that regulates the coordinated growth and differentiation that establishes the non-random anterior-posterior spatial arrangement of the neural plate.	tmpzr1t_l9r_go_relaxed.owl	neural plate anterior/posterior pattern formation													biological_process											owl:Class	
GO:0033848	biolink:NamedThing	N2-(2-carboxyethyl)arginine synthase activity	Catalysis of the reaction: D-glyceraldehyde 3-phosphate + L-arginine = N(2)-(2-carboxyethyl)-L-arginine + H(+) + phosphate.	tmpzr1t_l9r_go_relaxed.owl	N2-(2-carboxyethyl)arginine synthetase activity|glyceraldehyde-3-phosphate:L-arginine 2-N-(2-hydroxy-3-oxopropyl) transferase (2-carboxyethyl-forming) activity|glyceraldehyde-3-phosphate:L-arginine N2-(2-hydroxy-3-oxopropyl) transferase (2-carboxyethyl-forming) activity|CEAS|CEA synthetase activity				EC:2.5.1.66|KEGG_REACTION:R05465|MetaCyc:2.5.1.66-RXN|RHEA:10556									molecular_function											owl:Class	
GO:1902394	biolink:NamedThing	positive regulation of exodeoxyribonuclease activity	Any process that activates or increases the frequency, rate or extent of exodeoxyribonuclease activity.	tmpzr1t_l9r_go_relaxed.owl	upregulation of exodeoxyribonuclease activity|activation of exodeoxyribonuclease activity|up-regulation of exodeoxyribonuclease activity|up regulation of exodeoxyribonuclease activity							jl	2013-09-11T14:56:38Z					biological_process											owl:Class	
GO:0008104	biolink:NamedThing	protein localization	Any process in which a protein is transported to, or maintained in, a specific location.	tmpzr1t_l9r_go_relaxed.owl	asymmetric protein localisation|establishment and maintenance of protein localization|protein localisation|establishment and maintenance of asymmetric protein localization|asymmetric protein localization											GO:0008105		biological_process											owl:Class	
GO:0050790	biolink:NamedThing	regulation of catalytic activity	Any process that modulates the activity of an enzyme.	tmpzr1t_l9r_go_relaxed.owl	regulation of metalloenzyme activity|regulation of enzyme activity											GO:0048552		biological_process											owl:Class	
GO:1905294	biolink:NamedThing	positive regulation of neural crest cell differentiation	Any process that activates or increases the frequency, rate or extent of neural crest cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	activation of neural crest cell differentiation|upregulation of neural crest cell differentiation|up-regulation of neural crest cell differentiation|up regulation of neural crest cell differentiation							rl	2016-06-28T15:02:16Z					biological_process											owl:Class	
GO:0043410	biolink:NamedThing	positive regulation of MAPK cascade	Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the MAPK cascade.	tmpzr1t_l9r_go_relaxed.owl	stimulation of MAPK cascade|activation of MAPKKK cascade|positive regulation of MAP kinase cascade|stimulation of MAPKKK cascade|up regulation of MAPKKK cascade|upregulation of MAPKKK cascade|upregulation of MAPK cascade|positive regulation of mitogen-activated protein kinase cascade|activation of MAPK cascade|up-regulation of MAPKKK cascade|up-regulation of MAPK cascade|positive regulation of mitogen activated protein kinase kinase kinase cascade|positive regulation of MAPKKK cascade|positive regulation of MAP kinase kinase kinase cascade|positive regulation of mitogen-activated protein kinase kinase kinase cascade													biological_process											owl:Class	
GO:0043362	biolink:NamedThing	nucleate erythrocyte maturation	A developmental process, independent of morphogenetic (shape) change, that is required for a nucleate erythrocyte to attain its fully functional state. A nucleate erythrocyte is an erythrocyte with a nucleus.	tmpzr1t_l9r_go_relaxed.owl	nucleate RBC maturation|nucleate red blood cell maturation													biological_process											owl:Class	
GO:0043249	biolink:NamedThing	erythrocyte maturation	A developmental process, independent of morphogenetic (shape) change, that is required for an erythrocyte to attain its fully functional state.	tmpzr1t_l9r_go_relaxed.owl	red blood cell maturation|RBC maturation													biological_process											owl:Class	
GO:0039662	biolink:NamedThing	host cell outer membrane	A lipid bilayer that forms the outermost layer of the cell envelope, occurring in a host cell.	tmpzr1t_l9r_go_relaxed.owl	host cell envelope outer membrane|outer membrane of host cell							bf	2013-08-25T10:48:41Z					cellular_component											owl:Class	
GO:0044384	biolink:NamedThing	host outer membrane	The external membrane of Gram-negative bacteria or certain organelles such as mitochondria and chloroplasts; freely permeable to most ions and metabolites, occurring in a host cell.	tmpzr1t_l9r_go_relaxed.owl	host cell outer membrane					This term covers the outer membrane of the host cell envelope or the outer membrane of a host organelle. For the outer layer of the host cell envelope specifically, see host cell outer membrane ; GO:0039662.		jl	2011-12-13T04:02:07Z					cellular_component											owl:Class	
GO:0002792	biolink:NamedThing	negative regulation of peptide secretion	Any process that stops, prevents, or reduces the frequency, rate, or extent of peptide secretion.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of peptide secretion|downregulation of peptide secretion|inhibition of peptide secretion|down regulation of peptide secretion													biological_process											owl:Class	
GO:0032694	biolink:NamedThing	negative regulation of interleukin-11 production	Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-11 production.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of interleukin-11 biosynthetic process|inhibition of interleukin-11 production|downregulation of interleukin-11 production|down regulation of interleukin-11 production|negative regulation of IL-11 production|down-regulation of interleukin-11 production|negative regulation of interleukin-11 secretion											GO:0045364|GO:0150170		biological_process											owl:Class	
GO:0062014	biolink:NamedThing	negative regulation of small molecule metabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of a small molecule metabolic process.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of small molecule metabolism							dph	2018-03-19T14:27:23Z					biological_process											owl:Class	
GO:0070239	biolink:NamedThing	regulation of activated T cell autonomous cell death	Any process that modulates the occurrence or rate of activated T cell autonomous cell death.	tmpzr1t_l9r_go_relaxed.owl	regulation of activated cell autonomous cell death|regulation of activated T-lymphocyte autonomous cell death|regulation of activated T-cell autonomous cell death|regulation of ACAD|regulation of activated T cell apoptosis|regulation of activated T lymphocyte autonomous cell death													biological_process											owl:Class	
GO:0005337	biolink:NamedThing	nucleoside transmembrane transporter activity	Enables the transfer of a nucleoside, a nucleobase linked to either beta-D-ribofuranose (ribonucleoside) or 2-deoxy-beta-D-ribofuranose, (a deoxyribonucleotide) from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	intracellular nucleoside transmembrane transporter activity				Reactome:R-HSA-727740|Reactome:R-HSA-727768|Reactome:R-HSA-5628807|Reactome:R-HSA-109529|Reactome:R-HSA-109536|Reactome:R-HSA-109534|Reactome:R-HSA-727749|Reactome:R-HSA-109527|Reactome:R-HSA-727767									molecular_function											owl:Class	
GO:0070372	biolink:NamedThing	regulation of ERK1 and ERK2 cascade	Any process that modulates the frequency, rate or extent of signal transduction mediated by the ERK1 and ERK2 cascade.	tmpzr1t_l9r_go_relaxed.owl	regulation of ERK1 and ERK2 signaling pathway|regulation of ERK2 cascade|regulation of ERK1 cascade|regulation of MAPK1 cascade|regulation of ERK1/2 cascade|regulation of ERK cascade|regulation of ERK1 and ERK2 signalling pathway|regulation of MAPK3 cascade													biological_process											owl:Class	
GO:1902890	biolink:NamedThing	regulation of root hair elongation	Any process that modulates the frequency, rate or extent of root hair elongation.	tmpzr1t_l9r_go_relaxed.owl								als	2014-04-07T13:46:40Z					biological_process											owl:Class	
GO:0004321	biolink:NamedThing	fatty-acyl-CoA synthase activity	Catalysis of the reaction: acetyl-CoA + n malonyl-CoA + 2n NADH + 2n NADPH + 4n H+ = a long-chain acyl-CoA + n CoA + n CO2 + 2n NAD+ + 2n NADP+.	tmpzr1t_l9r_go_relaxed.owl	acyl-CoA:malonyl-CoA C-acyltransferase (decarboxylating, oxoacyl- and enoyl- reducing)|fatty acyl CoA synthase activity|yeast fatty acid synthase activity				EC:2.3.1.86|RHEA:22896|MetaCyc:FATTY-ACYL-COA-SYNTHASE-RXN									molecular_function											owl:Class	
GO:0010748	biolink:NamedThing	negative regulation of long-chain fatty acid import across plasma membrane	Any process that decreases the rate, frequency or extent of plasma membrane long-chain fatty acid transport. Plasma membrane long-chain fatty acid transport is the directed movement of long-chain fatty acids across the plasma membrane.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of plasma membrane long-chain fatty acid transport													biological_process											owl:Class	
GO:0051494	biolink:NamedThing	negative regulation of cytoskeleton organization	Any process that stops, prevents, or reduces the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures.	tmpzr1t_l9r_go_relaxed.owl	downregulation of cytoskeleton organization|negative regulation of cytoskeleton organization and biogenesis|down regulation of cytoskeleton organization|negative regulation of cytoskeleton organisation|down-regulation of cytoskeleton organization|inhibition of cytoskeleton organization													biological_process											owl:Class	
GO:0071645	biolink:NamedThing	positive regulation of chemokine (C-C motif) ligand 4 production	Any process that activates or increases the frequency, rate, or extent of production of chemokine (C-C motif) ligand 4.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of MIP-1b production|positive regulation of macrophage inflammatory protein production|positive regulation of CCL4 production							mah	2010-02-12T10:40:19Z					biological_process											owl:Class	
GO:0071643	biolink:NamedThing	regulation of chemokine (C-C motif) ligand 4 production	Any process that modulates the frequency, rate, or extent of production of chemokine (C-C motif) ligand 4.	tmpzr1t_l9r_go_relaxed.owl	regulation of MIP-1b production|regulation of CCL4 production|regulation of macrophage inflammatory protein production							mah	2010-02-12T10:39:51Z					biological_process											owl:Class	
GO:1902730	biolink:NamedThing	positive regulation of proteoglycan biosynthetic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteoglycans, any glycoprotein in which the carbohydrate units are glycosaminoglycans.	tmpzr1t_l9r_go_relaxed.owl	activation of proteoglycan anabolism|upregulation of proteoglycan formation|up regulation of proteoglycan biosynthetic process|upregulation of proteoglycan synthesis|up regulation of proteoglycan synthesis|up-regulation of proteoglycan formation|up regulation of proteoglycan formation|up regulation of proteoglycan biosynthesis|upregulation of proteoglycan anabolism|up-regulation of proteoglycan biosynthesis|activation of proteoglycan biosynthesis|up-regulation of proteoglycan biosynthetic process|positive regulation of proteoglycan formation|upregulation of proteoglycan biosynthesis|activation of proteoglycan formation|positive regulation of proteoglycan synthesis|up-regulation of proteoglycan synthesis|positive regulation of proteoglycan anabolism|up regulation of proteoglycan anabolism|activation of proteoglycan synthesis|positive regulation of proteoglycan biosynthesis|up-regulation of proteoglycan anabolism|upregulation of proteoglycan biosynthetic process|activation of proteoglycan biosynthetic process							mr	2014-02-24T16:10:52Z					biological_process											owl:Class	
GO:0010560	biolink:NamedThing	positive regulation of glycoprotein biosynthetic process	Any process that increases the rate, frequency, or extent of the chemical reactions and pathways resulting in the formation of a glycoprotein, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0035169	biolink:NamedThing	lymph gland plasmatocyte differentiation	The process in which a relatively unspecialized larval lymph gland-derived hemocyte precursor cell acquires the specialized features of the phagocytic blood-cell type, the plasmatocyte.	tmpzr1t_l9r_go_relaxed.owl	lymph gland plasmatocyte cell differentiation													biological_process											owl:Class	
GO:0042387	biolink:NamedThing	plasmatocyte differentiation	The process in which a hemocyte precursor cell acquires the characteristics of the phagocytic blood-cell type, the plasmatocyte. Plasmatocytes are a class of arthropod hemocytes important in the cellular defense response.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0021707	biolink:NamedThing	cerebellar granule cell differentiation	The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature cerebellar granule cell. Differentiation includes the processes involved in commitment of a neuroblast to a granule cell fate. A granule cell is a glutamatergic interneuron found in the cerebellar cortex.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0021533	biolink:NamedThing	cell differentiation in hindbrain	The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mature cells of the hindbrain. Differentiation includes the processes involved in commitment of a cell to a specific fate.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0034815	biolink:NamedThing	cis-4-(8-hydroxypyren-7-yl)-2-oxobut-3-enoate lyase activity	Catalysis of the reaction: cis-4-(8-hydroxypyren-7-yl)-2-oxobut-3-enoate = 10-oxabenzo(def)chrysen-9-one + formate + H+.	tmpzr1t_l9r_go_relaxed.owl					EC:4.1.3.-|UM-BBD_reactionID:r1135									molecular_function											owl:Class	
GO:0097628	biolink:NamedThing	distal tip cell migration	The orderly movement of a distal tip cell.	tmpzr1t_l9r_go_relaxed.owl								pr	2014-08-20T16:06:53Z					biological_process											owl:Class	
GO:0016477	biolink:NamedThing	cell migration	The controlled self-propelled movement of a cell from one site to a destination guided by molecular cues. Cell migration is a central process in the development and maintenance of multicellular organisms.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Cell_migration									biological_process											owl:Class	
GO:2000594	biolink:NamedThing	positive regulation of metanephric DCT cell differentiation	Any process that activates or increases the frequency, rate or extent of metanephric DCT cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of metanephric distal convoluted tubule cell differentiation							yaf	2011-04-11T01:40:41Z					biological_process											owl:Class	
GO:0009100	biolink:NamedThing	glycoprotein metabolic process	The chemical reactions and pathways involving glycoproteins, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide.	tmpzr1t_l9r_go_relaxed.owl	glycoprotein metabolism													biological_process											owl:Class	
GO:0019538	biolink:NamedThing	protein metabolic process	The chemical reactions and pathways involving a protein. Includes protein modification.	tmpzr1t_l9r_go_relaxed.owl	protein metabolic process and modification|protein metabolism|multicellular organismal protein metabolic process|protein metabolism and modification				Wikipedia:Protein_metabolism							GO:0044268|GO:0006411		biological_process											owl:Class	
GO:1900586	biolink:NamedThing	arugosin catabolic process	The chemical reactions and pathways resulting in the breakdown of arugosin.	tmpzr1t_l9r_go_relaxed.owl	arugosin breakdown|arugosin degradation|arugosin catabolism							di	2012-05-15T06:48:37Z					biological_process											owl:Class	
GO:1901575	biolink:NamedThing	organic substance catabolic process	The chemical reactions and pathways resulting in the breakdown of an organic substance, any molecular entity containing carbon.	tmpzr1t_l9r_go_relaxed.owl	organic substance catabolism|organic molecular entity degradation|organic molecular entity catabolism|organic substance degradation|organic molecular entity catabolic process|organic substance breakdown|organic molecular entity breakdown							pr	2012-11-05T11:04:36Z					biological_process											owl:Class	
GO:0045159	biolink:NamedThing	myosin II binding	Binding to a class II myosin, any member of the class of 'conventional' double-headed myosins that includes muscle myosin.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0017022	biolink:NamedThing	myosin binding	Binding to a myosin; myosins are any of a superfamily of molecular motor proteins that bind to actin and use the energy of ATP hydrolysis to generate force and movement along actin filaments.	tmpzr1t_l9r_go_relaxed.owl	myosin phosphatase myosin binding													molecular_function											owl:Class	
GO:0033546	biolink:NamedThing	myo-inositol hexakisphosphate biosynthetic process, via inositol 1,3,4-trisphosphate	The chemical reactions and pathways resulting in the formation of 1D-myo-inositol 1,2,3,4,5,6-hexakisphosphate, phytate, by a pathway using inositol 1,4,5-trisphosphate produced from phosphatidylinositol 4,5-biphosphate hydrolysis by phospholipase C; in this pathway, inositol 1,4,5-trisphosphate is first converted to inositol 1,3,4-trisphosphate, and then phosphorylated further.	tmpzr1t_l9r_go_relaxed.owl	myo-inositol hexakisphosphate biosynthesis, via inositol 1,3,4-trisphosphate|myo-inositol hexakisphosphate formation, via inositol 1,3,4-trisphosphate|myo-inositol hexakisphosphate anabolism, via inositol 1,3,4-trisphosphate|myo-inositol hexakisphosphate synthesis, via inositol 1,3,4-trisphosphate|phytate biosynthetic process, via inositol 1,3,4-trisphosphate|phytate biosynthesis, via inositol 1,3,4-trisphosphate				MetaCyc:PWY-6554									biological_process											owl:Class	
GO:0033545	biolink:NamedThing	myo-inositol hexakisphosphate biosynthetic process, lipid-dependent	The chemical reactions and pathways resulting in the formation of 1D-myo-inositol 1,2,3,4,5,6-hexakisphosphate, phytate, by a pathway using inositol 1,4,5-trisphosphate produced from phosphatidylinositol 4,5-biphosphate hydrolysis by phospholipase C.	tmpzr1t_l9r_go_relaxed.owl	myo-inositol hexakisphosphate biosynthesis, lipid-dependent|myo-inositol hexakisphosphate synthesis, lipid-dependent|myo-inositol hexakisphosphate anabolism, lipid-dependent|phytate biosynthetic process, lipid-dependent|phytate biosynthesis, lipid-dependent|myo-inositol hexakisphosphate formation, lipid-dependent				MetaCyc:PWY-6555									biological_process											owl:Class	
GO:1902931	biolink:NamedThing	negative regulation of alcohol biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of alcohol biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	downregulation of alcohol biosynthetic process|inhibition of alcohol anabolism|down-regulation of alcohol biosynthesis|down regulation of alcohol anabolism|down-regulation of alcohol biosynthetic process|down-regulation of alcohol synthesis|down-regulation of alcohol formation|down-regulation of alcohol anabolism|downregulation of alcohol anabolism|inhibition of alcohol synthesis|downregulation of alcohol formation|downregulation of alcohol biosynthesis|negative regulation of alcohol synthesis|inhibition of alcohol formation|inhibition of alcohol biosynthetic process|inhibition of alcohol biosynthesis|down regulation of alcohol biosynthetic process|downregulation of alcohol synthesis|down regulation of alcohol synthesis|negative regulation of alcohol anabolism|down regulation of alcohol formation|negative regulation of alcohol biosynthesis|negative regulation of alcohol formation|down regulation of alcohol biosynthesis|negative regulation of solventogenesis							tt	2014-04-22T21:55:13Z					biological_process											owl:Class	
GO:1902930	biolink:NamedThing	regulation of alcohol biosynthetic process	Any process that modulates the frequency, rate or extent of alcohol biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of alcohol formation|regulation of solventogenesis|regulation of alcohol biosynthesis|regulation of alcohol synthesis|regulation of alcohol anabolism							tt	2014-04-22T21:55:03Z					biological_process											owl:Class	
GO:0043280	biolink:NamedThing	positive regulation of cysteine-type endopeptidase activity involved in apoptotic process	Any process that activates or increases the activity of a cysteine-type endopeptidase involved in the apoptotic process.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of caspase activity|stimulation of caspase activity|upregulation of caspase activity|activation of caspase activity|up regulation of caspase activity|up-regulation of caspase activity													biological_process											owl:Class	
GO:2001056	biolink:NamedThing	positive regulation of cysteine-type endopeptidase activity	Any process that activates or increases the frequency, rate or extent of cysteine-type endopeptidase activity.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of thiol endopeptidase activity|positive regulation of lysosomal cysteine-type endopeptidase							pr	2011-09-09T08:53:43Z					biological_process											owl:Class	
GO:0014041	biolink:NamedThing	regulation of neuron maturation	Any process that modulates the frequency, rate or extent of neuron maturation, the process leading to the attainment of the full functional capacity of a neuron. This process is independent of morphogenetic change.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0019369	biolink:NamedThing	arachidonic acid metabolic process	The chemical reactions and pathways involving arachidonic acid, a straight chain fatty acid with 20 carbon atoms and four double bonds per molecule. Arachidonic acid is the all-Z-(5,8,11,14)-isomer.	tmpzr1t_l9r_go_relaxed.owl	arachidonic acid metabolism				Wikipedia:Arachidonic_acid									biological_process											owl:Class	
GO:0033559	biolink:NamedThing	unsaturated fatty acid metabolic process	The chemical reactions and pathways involving an unsaturated fatty acid, any fatty acid containing one or more double bonds between carbon atoms.	tmpzr1t_l9r_go_relaxed.owl	unsaturated fatty acid metabolism				MetaCyc:PWY-782|MetaCyc:PWY-762									biological_process											owl:Class	
GO:0031724	biolink:NamedThing	CXCR5 chemokine receptor binding	Binding to a CXCR5 chemokine receptor.	tmpzr1t_l9r_go_relaxed.owl	type 1 Burkitt's lymphoma receptor binding|CXCR5 chemokine receptor ligand													molecular_function											owl:Class	
GO:0045236	biolink:NamedThing	CXCR chemokine receptor binding	Binding to a chemokine receptor in the CXCR family.	tmpzr1t_l9r_go_relaxed.owl	CXC chemokine receptor ligand|C-X-C chemokine receptor ligand|alpha chemokine receptor binding|alpha chemokine receptor ligand													molecular_function											owl:Class	
GO:0061077	biolink:NamedThing	chaperone-mediated protein folding	The process of inhibiting aggregation and assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure that is dependent on interaction with a chaperone.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-04-06T03:28:55Z					biological_process											owl:Class	
GO:0006457	biolink:NamedThing	protein folding	The process of assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure.	tmpzr1t_l9r_go_relaxed.owl	glycoprotein-specific chaperone activity|co-chaperonin activity|alpha-tubulin folding|chaperone activity|chaperonin-mediated tubulin folding|chaperonin ATPase activity|protein complex assembly, multichaperone pathway|beta-tubulin folding|co-chaperone activity|non-chaperonin molecular chaperone ATPase activity				Wikipedia:Protein_folding							GO:0007025|GO:0007024|GO:0007022		biological_process											owl:Class	
GO:0043104	biolink:NamedThing	positive regulation of GTP cyclohydrolase I activity	Any process that activates or increases the activity of the enzyme GTP cyclohydrolase I.	tmpzr1t_l9r_go_relaxed.owl	stimulation of GTP cyclohydrolase I activity|activation of GTP cyclohydrolase I activity|up-regulation of GTP cyclohydrolase I activity|upregulation of GTP cyclohydrolase I activity|up regulation of GTP cyclohydrolase I activity													biological_process											owl:Class	
GO:0043095	biolink:NamedThing	regulation of GTP cyclohydrolase I activity	Any process that modulates the activity of the enzyme GTP cyclohydrolase I.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1900233	biolink:NamedThing	positive regulation of single-species biofilm formation on inanimate substrate	Any process that activates or increases the frequency, rate or extent of single-species biofilm formation on inanimate substrate.	tmpzr1t_l9r_go_relaxed.owl	activation of single-species biofilm formation on inanimate substrate|up regulation of single-species biofilm formation on inanimate substrate|up-regulation of single-species biofilm formation on inanimate substrate|upregulation of single-species biofilm formation on inanimate substrate							di	2012-03-23T04:40:53Z					biological_process											owl:Class	
GO:1900231	biolink:NamedThing	regulation of single-species biofilm formation on inanimate substrate	Any process that modulates the frequency, rate or extent of single-species biofilm formation on inanimate substrate.	tmpzr1t_l9r_go_relaxed.owl								di	2012-03-23T04:40:35Z					biological_process											owl:Class	
GO:0010769	biolink:NamedThing	regulation of cell morphogenesis involved in differentiation	Any process that modulates the frequency, rate or extent of cell morphogenesis contributing to cell differentiation. Cell morphogenesis involved in differentiation is the change in form (cell shape and size) that occurs when relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1903960	biolink:NamedThing	negative regulation of anion transmembrane transport	Any process that stops, prevents or reduces the frequency, rate or extent of anion transmembrane transport.	tmpzr1t_l9r_go_relaxed.owl	inhibition of anion transmembrane transport|downregulation of anion transmembrane transport|down-regulation of anion transmembrane transport|down regulation of anion transmembrane transport							pr	2015-02-25T13:52:35Z					biological_process											owl:Class	
GO:0032232	biolink:NamedThing	negative regulation of actin filament bundle assembly	Any process that stops, prevents, or reduces the frequency, rate or extent of the assembly of actin filament bundles.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of actin filament bundle formation|downregulation of actin filament bundle formation|inhibition of actin filament bundle formation|down regulation of actin filament bundle formation													biological_process											owl:Class	
GO:1900971	biolink:NamedThing	regulation of sarcinapterin biosynthetic process	Any process that modulates the frequency, rate or extent of sarcinapterin biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of sarcinapterin formation|regulation of sarcinapterin synthesis|regulation of sarcinapterin biosynthesis|regulation of sarcinapterin anabolism							tt	2012-06-14T03:59:44Z					biological_process											owl:Class	
GO:0009179	biolink:NamedThing	purine ribonucleoside diphosphate metabolic process	The chemical reactions and pathways involving purine ribonucleoside diphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with diphosphate on the sugar.	tmpzr1t_l9r_go_relaxed.owl	purine ribonucleoside diphosphate metabolism													biological_process											owl:Class	
GO:0009185	biolink:NamedThing	ribonucleoside diphosphate metabolic process	The chemical reactions and pathways involving a ribonucleoside diphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with diphosphate on the sugar.	tmpzr1t_l9r_go_relaxed.owl	ribonucleoside diphosphate metabolism													biological_process											owl:Class	
GO:1900671	biolink:NamedThing	negative regulation of F-9775A biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of F-9775A biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of F-9775A synthesis|inhibition of F-9775A biosynthetic process|inhibition of F-9775A synthesis|inhibition of F-9775A anabolism|down regulation of F-9775A formation|downregulation of F-9775A formation|negative regulation of F-9775A biosynthesis|down regulation of F-9775A anabolism|negative regulation of F-9775A anabolism|inhibition of F-9775A biosynthesis|down-regulation of F-9775A biosynthetic process|negative regulation of F-9775A synthesis|down-regulation of F-9775A biosynthesis|down regulation of F-9775A biosynthesis|down-regulation of F-9775A anabolism|down regulation of F-9775A biosynthetic process|down-regulation of F-9775A formation|downregulation of F-9775A anabolism|negative regulation of F-9775A formation|inhibition of F-9775A formation|down regulation of F-9775A synthesis|downregulation of F-9775A synthesis|downregulation of F-9775A biosynthetic process|downregulation of F-9775A biosynthesis							di	2012-05-22T04:24:30Z					biological_process											owl:Class	
GO:2000658	biolink:NamedThing	positive regulation of apolipoprotein binding	Any process that activates or increases the frequency, rate or extent of apolipoprotein binding.	tmpzr1t_l9r_go_relaxed.owl								vk	2011-05-02T05:33:46Z					biological_process											owl:Class	
GO:0034452	biolink:NamedThing	dynactin binding	Binding to a dynactin complex; a large protein complex that activates dynein-based motor activity.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0019100	biolink:NamedThing	male germ-line sex determination	The determination of sex and sexual phenotype in a male organism's germ line.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0018992	biolink:NamedThing	germ-line sex determination	The determination of sex and sexual phenotype in an organism's germ line.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1904567	biolink:NamedThing	response to wortmannin	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a wortmannin stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to wartmannin							sl	2015-08-19T16:22:28Z					biological_process											owl:Class	
GO:0050833	biolink:NamedThing	pyruvate transmembrane transporter activity	Enables the transfer of pyruvate, 2-oxopropanoate, from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	monocarboxylate (lactate, pyruvate, mevalonate) uptake/efflux porter activity				Reactome:R-HSA-372342									molecular_function											owl:Class	
GO:0008028	biolink:NamedThing	monocarboxylic acid transmembrane transporter activity	Enables the transfer of monocarboxylic acids from one side of a membrane to the other. A monocarboxylic acid is an organic acid with one COOH group.	tmpzr1t_l9r_go_relaxed.owl	prostaglandin/thromboxane transporter activity|monocarboxylate carrier				Reactome:R-HSA-5624211|Reactome:R-HSA-433698|Reactome:R-HSA-9645220|Reactome:R-HSA-429749							GO:0008505		molecular_function											owl:Class	
GO:0010285	biolink:NamedThing	L,L-diaminopimelate aminotransferase activity	Catalysis of the reaction: 2-oxoglutarate + LL-2,6-diaminopimelate = (S)-2,3,4,5-tetrahydrodipicolinate + L-glutamate + H(2)O + H(+).	tmpzr1t_l9r_go_relaxed.owl	LL-DAP-AT activity|LL-diaminopimelate aminotransferase activity|LL-2,6-diaminoheptanedioate:2-oxoglutarate aminotransferase activity|LL-diaminopimelate transaminase activity|LL-DAP aminotransferase activity				RHEA:23988|KEGG_REACTION:R07613|MetaCyc:RXN-7737|EC:2.6.1.83							GO:0043742		molecular_function											owl:Class	
GO:0036503	biolink:NamedThing	ERAD pathway	The protein catabolic pathway which targets endoplasmic reticulum (ER)-resident proteins for degradation by the cytoplasmic proteasome. It begins with recognition of the ER-resident protein, includes retrotranslocation (dislocation) of the protein from the ER to the cytosol, protein modifications necessary for correct substrate transfer (e.g. ubiquitination), transport of the protein to the proteasome, and ends with degradation of the protein by the cytoplasmic proteasome.	tmpzr1t_l9r_go_relaxed.owl	endoplasmic reticulum-associated degradation|endoplasmic reticulum-associated protein degradation pathway|ER-associated degradation pathway|protein degradation by ERAD					ER-associated protein degradation (ERAD) pathways target misfolded ER lumenal proteins (ERAD-L), ER membrane proteins (ERAD-M), and ER proteins with misfolded cytosolic domains (ERAD-C) by recognizing aberrant proteins, retrotranslocating these substrates to the cytosol, followed by substrate ubiquitination and proteosomal-mediated degradation. In contrast the stress-induced homeostatically regulated protein degradation (SHRED) pathway (GO:0120174), although inducible by stress, targets diverse ER membrane, and cytosolic proteins as well as numerous other native proteins in the absence of stress. Stress results in the protease-mediated (Nma111p) generation of a Roq1p cleavage product that then binds to the type-1 active site of Ubr1p, altering its substrate specificity, and leading to the proteasome-mediated degradation of both misfolded and native proteins. Although the SHRED pathway may contain some components in common with ERAD pathways (GO:0036503), such as UBR1, RAD6 and CDC48, other ERAD components, such as HRD1 and DOA10, do not appear to be involved, and as such these pathways are currently considered to be distinct.		bf	2015-05-14T11:43:06Z					biological_process											owl:Class	
GO:0010498	biolink:NamedThing	proteasomal protein catabolic process	The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds that is mediated by the proteasome.	tmpzr1t_l9r_go_relaxed.owl	proteasome-mediated protein catabolism|proteasome-mediated protein catabolic process													biological_process											owl:Class	
GO:0015105	biolink:NamedThing	arsenite transmembrane transporter activity	Enables the transfer of arsenite from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0045726	biolink:NamedThing	positive regulation of integrin biosynthetic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of integrins.	tmpzr1t_l9r_go_relaxed.owl	up regulation of integrin biosynthetic process|positive regulation of integrin anabolism|positive regulation of integrin biosynthesis|activation of integrin biosynthetic process|positive regulation of integrin formation|stimulation of integrin biosynthetic process|positive regulation of integrin synthesis|up-regulation of integrin biosynthetic process|upregulation of integrin biosynthetic process													biological_process											owl:Class	
GO:0045113	biolink:NamedThing	regulation of integrin biosynthetic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of integrins.	tmpzr1t_l9r_go_relaxed.owl	regulation of integrin anabolism|regulation of integrin biosynthesis|regulation of integrin formation|regulation of integrin synthesis													biological_process											owl:Class	
GO:1901165	biolink:NamedThing	positive regulation of trophoblast cell migration	Any process that activates or increases the frequency, rate or extent of trophoblast cell migration.	tmpzr1t_l9r_go_relaxed.owl	up regulation of trophoblast cell migration|activation of trophoblast cell migration|up-regulation of trophoblast cell migration|upregulation of trophoblast cell migration							vk	2012-07-19T07:53:35Z					biological_process											owl:Class	
GO:0004843	biolink:NamedThing	thiol-dependent deubiquitinase	Catalysis of the thiol-dependent hydrolysis of a peptide bond formed by the C-terminal glycine of ubiquitin and another protein.	tmpzr1t_l9r_go_relaxed.owl	ubiquitin hydrolase activity|thiol-dependent ubiquitin-specific protease activity|deubiquitinase activity|ubiquitin-specific protease activity|thiol-dependent ubiquitinyl hydrolase activity|deubiquitinase|deubiquitinating enzyme|UCH2|ubiquitinyl hydrolase 1 activity|ubiquitin C-terminal hydrolase|deubiquitylase|ubiquitinyl hydrolase activity|UBP	https://github.com/geneontology/go-ontology/issues/19723			Reactome:R-HSA-6807206|EC:3.4.19.12|Reactome:R-HSA-5690080|Reactome:R-HSA-5696968|Reactome:R-HSA-5696564|Reactome:R-HSA-5690196|Reactome:R-HSA-5696465|Reactome:R-HSA-3215295|Reactome:R-HSA-8862184|Reactome:R-HSA-6781764|Reactome:R-HSA-2179291|Reactome:R-HSA-6781814|Reactome:R-HSA-5690157|Reactome:R-HSA-4641236|Reactome:R-HSA-5697009|Reactome:R-HSA-5696960|Reactome:R-HSA-8853503|Reactome:R-HSA-9653514|Reactome:R-HSA-5696914|Reactome:R-HSA-3640872|Reactome:R-HSA-5690759|Reactome:R-HSA-6782069|Reactome:R-HSA-5696627|Reactome:R-HSA-5689972|Reactome:R-HSA-9033478|Reactome:R-HSA-6782820|Reactome:R-HSA-5696958|Reactome:R-HSA-8865182|Reactome:R-HSA-5690152|Reactome:R-HSA-6783177|Reactome:R-HSA-870437|Reactome:R-HSA-8853514|Reactome:R-HSA-8853515|Reactome:R-HSA-5655466|Reactome:R-HSA-1358795|Reactome:R-HSA-5689950|Reactome:R-HSA-8873946|Reactome:R-HSA-6786171|Reactome:R-HSA-5696947|Reactome:R-HSA-9033491|Reactome:R-HSA-5688797|Reactome:R-HSA-5653770|Reactome:R-HSA-8853529|Reactome:R-HSA-5689973|Reactome:R-HSA-3215310|Reactome:R-HSA-5690159|Reactome:R-HSA-6781897|Reactome:R-HSA-5696600|Reactome:R-HSA-8875443|Reactome:R-HSA-6781779|Reactome:R-HSA-5691381|Reactome:R-HSA-5696872|Reactome:R-HSA-5690319|Reactome:R-HSA-6782628|Reactome:R-HSA-5696945|Reactome:R-HSA-5688837|Reactome:R-HSA-8986083|Reactome:R-HSA-8869456|Reactome:R-HSA-5696534|Reactome:R-HSA-6782106|Reactome:R-HSA-6807118|Reactome:R-HSA-5696605|Reactome:R-HSA-5690790|Reactome:R-HSA-5696997							GO:0036459		molecular_function											owl:Class	
GO:0008242	biolink:NamedThing	omega peptidase activity	Catalysis of the cleavage of non-standard peptide bonds releasing substituted amino acids such as pyroglutamate or cleave isopeptide bonds, such as many deubiquitinating enzymes.	tmpzr1t_l9r_go_relaxed.owl	peptidase activity, acting on peptides containing modified amino acids				EC:3.4.19.-									molecular_function											owl:Class	
GO:0031970	biolink:NamedThing	organelle envelope lumen	The region between the inner and outer lipid bilayers of an organelle envelope.	tmpzr1t_l9r_go_relaxed.owl	organelle intermembrane space													cellular_component											owl:Class	
GO:0070013	biolink:NamedThing	intracellular organelle lumen	An organelle lumen that is part of an intracellular organelle.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:1904326	biolink:NamedThing	negative regulation of circadian sleep/wake cycle, wakefulness	Any process that stops, prevents or reduces the frequency, rate or extent of circadian sleep/wake cycle, wakefulness.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of circadian sleep/wake cycle, wakefulness|down regulation of circadian sleep/wake cycle, wakefulness|inhibition of circadian sleep/wake cycle, wakefulness|downregulation of circadian sleep/wake cycle, wakefulness							sl	2015-06-10T20:18:45Z					biological_process											owl:Class	
GO:0120109	biolink:NamedThing	mitotic telomere clustering and tethering at nuclear periphery	The process in which the telomeres are gathered together to a small number of foci per chromosome (usually one per chromosome or fewer), and moved to and tethered at the nuclear periphery, as part of a mitotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl								krc	2017-11-01T18:04:37Z					biological_process											owl:Class	
GO:0034397	biolink:NamedThing	telomere localization	Any process in which a telomere is transported to, and/or maintained in, a specific location.	tmpzr1t_l9r_go_relaxed.owl	telomere localisation													biological_process											owl:Class	
GO:0072709	biolink:NamedThing	cellular response to sorbitol	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sorbitol stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to glucitol							mah	2012-04-11T03:41:03Z					biological_process											owl:Class	
GO:0071322	biolink:NamedThing	cellular response to carbohydrate stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbohydrate stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-12-10T05:13:33Z					biological_process											owl:Class	
GO:0010463	biolink:NamedThing	mesenchymal cell proliferation	The multiplication or reproduction of cells, resulting in the expansion of a mesenchymal cell population. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0102398	biolink:NamedThing	dTDP-3-amino-4-oxo-2,3,6-trideoxy-alpha-D-glucose N-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine  + dTDP-3-amino-4-dehydro-2,3,6-trideoxy-alpha-D-glucose <=> S-adenosyl-L-homocysteine  + dTDP-3-N-methylamino-4-oxo-2,3,6-trideoxy-alpha-D-glucose + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-13657									molecular_function											owl:Class	
GO:1902572	biolink:NamedThing	negative regulation of serine-type peptidase activity	Any process that stops, prevents or reduces the frequency, rate or extent of serine-type peptidase activity.	tmpzr1t_l9r_go_relaxed.owl	down regulation of serine-type peptidase activity|down-regulation of serine-type peptidase activity|down-regulation of serine protease activity|inhibition of serine-type peptidase activity|downregulation of serine-type peptidase activity|downregulation of serine protease activity|inhibition of serine protease activity|down regulation of serine protease activity|negative regulation of serine protease activity							krc	2013-12-10T18:17:07Z					biological_process											owl:Class	
GO:0043806	biolink:NamedThing	keto acid formate lyase activity	Catalysis of the reaction: 2-oxobutanoate + CoA = propionyl-CoA + formate.	tmpzr1t_l9r_go_relaxed.owl	keto-acid formate lyase activity|keto-acid formate acetyltransferase|keto-acid formate-lyase activity				MetaCyc:KETOBUTFORMLY-RXN|EC:2.3.1.-									molecular_function											owl:Class	
GO:0032009	biolink:NamedThing	early phagosome	A membrane-bounded intracellular vesicle as initially formed upon the ingestion of particulate material by phagocytosis.	tmpzr1t_l9r_go_relaxed.owl	early phagocytic vesicle													cellular_component											owl:Class	
GO:0045335	biolink:NamedThing	phagocytic vesicle	A membrane-bounded intracellular vesicle that arises from the ingestion of particulate material by phagocytosis.	tmpzr1t_l9r_go_relaxed.owl	phagosome				Wikipedia:Phagosome									cellular_component											owl:Class	
GO:0017012	biolink:NamedThing	protein-phytochromobilin linkage	The linkage of the chromophore phytochromobilin to phycocyanin or allophycocyanin.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0133									biological_process											owl:Class	
GO:0017007	biolink:NamedThing	protein-bilin linkage	The covalent linkage of bilin and a protein.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0061075	biolink:NamedThing	positive regulation of neural retina development	Any process that increases the rate, frequency, or extent of neural retina development, the progression of the neural retina over time from its initial formation to the mature structure. The neural retina is the part of the retina that contains neurons and photoreceptor cells.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-03-16T11:59:48Z					biological_process											owl:Class	
GO:1905556	biolink:NamedThing	ciliary vesicle assembly	The aggregation, arrangement and bonding together of a set of components to form a ciliary vesicle. Multiple smaller vesicles dock to the transitional fibers on a mature basal body and then fuse together to form a larger single vesicle. This then fuses with the plasma membrane and forms the ciliary membrane.	tmpzr1t_l9r_go_relaxed.owl	CV assembly|primary ciliary vesicle assembly|primary ciliary vesicle formation|ciliary vesicle formation|CV formation							pr	2016-10-13T09:31:06Z					biological_process											owl:Class	
GO:0016050	biolink:NamedThing	vesicle organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a vesicle.	tmpzr1t_l9r_go_relaxed.owl	vesicle organisation|vesicle organization and biogenesis													biological_process											owl:Class	
GO:0015839	biolink:NamedThing	cadaverine transport	The directed movement of cadaverine, 1,5-pentanediamine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0071721	biolink:NamedThing	sodium-independent thromboxane transport	The directed, sodium-independent, movement of thromboxanes into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A thromboxane is any of a class of oxygenated oxane derivatives, originally derived from prostaglandin precursors in platelets, that stimulate aggregation of platelets and constriction of blood vessels.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-03-10T03:10:45Z					biological_process											owl:Class	
GO:0071717	biolink:NamedThing	thromboxane transport	The directed movement of thromboxanes into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A thromboxane is any of a class of oxygenated oxane derivatives, originally derived from prostaglandin precursors in platelets, that stimulate aggregation of platelets and constriction of blood vessels.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-03-10T03:03:49Z					biological_process											owl:Class	
GO:0000296	biolink:NamedThing	spermine transport	The directed movement of spermine, N,N-bis(3-aminopropyl)-1,4-diaminobutane, a polyamine formed by the transfer of a propylamine group from decarboxylated S-adenosylmethionine to spermidine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0044503	biolink:NamedThing	modulation of G protein-coupled receptor activity in other organism	The process in which an organism effects a change in the activity of a G protein-coupled receptor in a second organism.	tmpzr1t_l9r_go_relaxed.owl	modulation of G-protein coupled receptor activity in other organism							jl	2012-02-23T04:20:07Z					biological_process											owl:Class	
GO:0006234	biolink:NamedThing	TTP biosynthetic process	The chemical reactions and pathways resulting in the formation of TTP, ribosylthymine triphosphate.	tmpzr1t_l9r_go_relaxed.owl	TTP formation|TTP anabolism|TTP synthesis|TTP biosynthesis													biological_process											owl:Class	
GO:1901934	biolink:NamedThing	bicyclogermacrene biosynthetic process	The chemical reactions and pathways resulting in the formation of bicyclogermacrene.	tmpzr1t_l9r_go_relaxed.owl	bicyclogermacrene biosynthesis|bicyclogermacrene anabolism|bicyclogermacrene formation|bicyclogermacrene synthesis							ms	2013-02-18T14:55:01Z					biological_process											owl:Class	
GO:0051762	biolink:NamedThing	sesquiterpene biosynthetic process	The chemical reactions and pathways resulting in the formation of sesquiterpenes, any of a class of terpenes of the formula C15H24 or a derivative of such a terpene.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0032344	biolink:NamedThing	regulation of aldosterone metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving aldosterone.	tmpzr1t_l9r_go_relaxed.owl	regulation of aldosterone metabolism													biological_process											owl:Class	
GO:0034477	biolink:NamedThing	U6 snRNA 3'-end processing	Any process involved in forming the mature 3' end of a U6 snRNA molecule.	tmpzr1t_l9r_go_relaxed.owl	U6 snRNA 3' end processing													biological_process											owl:Class	
GO:0034472	biolink:NamedThing	snRNA 3'-end processing	Any process involved in forming the mature 3' end of an snRNA molecule.	tmpzr1t_l9r_go_relaxed.owl	snRNA 3' end processing													biological_process											owl:Class	
GO:0003330	biolink:NamedThing	regulation of extracellular matrix constituent secretion	Any process that modulates the rate, frequency, or extent of the controlled release of molecules that form the extracellular matrix, including carbohydrates and glycoproteins by a cell or a group of cells.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-11-02T02:07:40Z					biological_process											owl:Class	
GO:1903530	biolink:NamedThing	regulation of secretion by cell	Any process that modulates the frequency, rate or extent of secretion by cell.	tmpzr1t_l9r_go_relaxed.owl	regulation of cellular secretion							pm	2014-10-08T13:24:59Z					biological_process											owl:Class	
GO:0000395	biolink:NamedThing	mRNA 5'-splice site recognition	Recognition of the intron 5'-splice site by components of the assembling spliceosome.	tmpzr1t_l9r_go_relaxed.owl	spliceosomal E complex formation|spliceosomal CC complex biosynthesis|U12-type nuclear mRNA 5' splice site recognition|spliceosomal commitment complex formation|nuclear mRNA 5'-splice site recognition|nuclear mRNA 5' splice site recognition|spliceosomal E complex biosynthesis|spliceosomal CC complex formation|U12-type nuclear mRNA 5'-splice site recognition|spliceosomal commitment complex biosynthesis|U2-type nuclear mRNA 5' splice site recognition|U2-type nuclear mRNA 5'-splice site recognition					Note that this step represents formation of the Commitment Complex (CC, in yeast) or the E complex (mammalian).						GO:0000368|GO:0000369		biological_process											owl:Class	
GO:0006376	biolink:NamedThing	mRNA splice site selection	Selection of a splice site by components of the assembling spliceosome.	tmpzr1t_l9r_go_relaxed.owl	spliceosomal E complex biosynthesis|spliceosomal commitment complex biosynthesis|spliceosomal commitment complex formation|spliceosomal E complex formation													biological_process											owl:Class	
GO:0072280	biolink:NamedThing	establishment of planar polarity involved in metanephric nephron morphogenesis	Coordinated organization of groups of cells in the plane of an epithelium that contributes to the shaping of a nephron in the metanephros.	tmpzr1t_l9r_go_relaxed.owl	establishment of planar cell polarity involved in metanephric nephron morphogenesis							mah	2010-04-01T03:17:18Z					biological_process											owl:Class	
GO:0015888	biolink:NamedThing	thiamine transport	The directed movement of thiamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Thiamine is vitamin B1, a water soluble vitamin present in fresh vegetables and meats, especially liver.	tmpzr1t_l9r_go_relaxed.owl	vitamin B1 transport|thiamin transport													biological_process											owl:Class	
GO:0033482	biolink:NamedThing	D-galacturonate biosynthetic process	The chemical reactions and pathways resulting in the formation of D-galacturonate, the D-enantiomer of galacturonate, the anion of galacturonic acid.	tmpzr1t_l9r_go_relaxed.owl	D-galacturonate synthesis|D-galacturonate formation|D-galacturonate anabolism|D-galacturonate biosynthesis													biological_process											owl:Class	
GO:0046396	biolink:NamedThing	D-galacturonate metabolic process	The chemical reactions and pathways involving D-galacturonate, the D-enantiomer of galacturonate, the anion of galacturonic acid. D-galacturonic acid is a component of plant gums and bacterial cell walls.	tmpzr1t_l9r_go_relaxed.owl	D-galacturonate metabolism													biological_process											owl:Class	
GO:0034341	biolink:NamedThing	response to interferon-gamma	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-gamma stimulus. Interferon-gamma is also known as type II interferon.	tmpzr1t_l9r_go_relaxed.owl	response to gamma-interferon|response to type II interferon|response to immune interferon|response to type II IFN													biological_process											owl:Class	
GO:0034097	biolink:NamedThing	response to cytokine	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytokine stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to cytokine stimulus													biological_process											owl:Class	
GO:1900885	biolink:NamedThing	negative regulation of tridecane biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of tridecane biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of tridecane synthesis|downregulation of tridecane synthesis|down regulation of tridecane anabolism|inhibition of tridecane anabolism|inhibition of tridecane formation|inhibition of tridecane biosynthetic process|negative regulation of tridecane formation|down regulation of tridecane biosynthesis|downregulation of tridecane biosynthetic process|down regulation of tridecane formation|down-regulation of tridecane formation|inhibition of tridecane biosynthesis|down-regulation of tridecane biosynthetic process|down regulation of tridecane synthesis|down regulation of tridecane biosynthetic process|downregulation of tridecane formation|down-regulation of tridecane synthesis|downregulation of tridecane biosynthesis|negative regulation of tridecane biosynthesis|down-regulation of tridecane anabolism|inhibition of tridecane synthesis|down-regulation of tridecane biosynthesis|downregulation of tridecane anabolism|negative regulation of tridecane anabolism							tt	2012-06-13T03:00:53Z					biological_process											owl:Class	
GO:1900894	biolink:NamedThing	negative regulation of tridecane metabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of tridecane metabolic process.	tmpzr1t_l9r_go_relaxed.owl	inhibition of tridecane metabolism|down regulation of tridecane metabolic process|inhibition of tridecane metabolic process|down regulation of tridecane metabolism|downregulation of tridecane metabolism|negative regulation of tridecane metabolism|down-regulation of tridecane metabolism|downregulation of tridecane metabolic process|down-regulation of tridecane metabolic process							tt	2012-06-13T03:15:03Z					biological_process											owl:Class	
GO:0046160	biolink:NamedThing	heme a metabolic process	The chemical reactions and pathways involving heme a, a derivative of heme found in cytochrome aa3.	tmpzr1t_l9r_go_relaxed.owl	heme a metabolism|haem a metabolic process|haem a metabolism													biological_process											owl:Class	
GO:0042168	biolink:NamedThing	heme metabolic process	The chemical reactions and pathways involving heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring.	tmpzr1t_l9r_go_relaxed.owl	heme metabolism|haem metabolic process|haem metabolism													biological_process											owl:Class	
GO:2000330	biolink:NamedThing	positive regulation of T-helper 17 cell lineage commitment	Any process that activates or increases the frequency, rate or extent of T-helper 17 cell lineage commitment.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of Th17 cell lineage commitment|positive regulation of T-helper 17 cell fate commitment|positive regulation of Th17 fate commitment							mah	2011-01-19T09:32:16Z					biological_process											owl:Class	
GO:2000328	biolink:NamedThing	regulation of T-helper 17 cell lineage commitment	Any process that modulates the frequency, rate or extent of T-helper 17 cell lineage commitment.	tmpzr1t_l9r_go_relaxed.owl	regulation of Th17 fate commitment|regulation of Th17 cell lineage commitment|regulation of T-helper 17 cell fate commitment							mah	2011-01-19T09:31:19Z					biological_process											owl:Class	
GO:0140571	biolink:NamedThing	transmembrane ascorbate ferrireductase activity	Oxidation of Fe(3+) to Fe(2+) on the outer side of a membrane coupled to the reduction of L-ascorbate to monodehydro-L-ascorbate radical on the inner side of a membrane. Electrons get transferred across the membrane during the reaction.	tmpzr1t_l9r_go_relaxed.owl	L-ascorbate-cytochrome-b5 reductase activity|L-ascorbate:ferricytochrome-b5 oxidoreductase activity|ascorbate-cytochrome b5 reductase activity				EC:7.2.1.3|MetaCyc:1.10.2.1-RXN|RHEA:30403			pg	2020-12-18T16:25:06Z					molecular_function											owl:Class	
GO:0015453	biolink:NamedThing	oxidoreduction-driven active transmembrane transporter activity	Primary active transport of a solute across a membrane, driven by exothermic flow of electrons from a reduced substrate to an oxidized substrate. Primary active transport is catalysis of the transport of a solute across a membrane, up the solute's concentration gradient, by binding the solute and undergoing a series of conformational changes. Transport works equally well in either direction and is driven by a primary energy source.	tmpzr1t_l9r_go_relaxed.owl	oxidoreduction-driven transporter				TC:3.D									molecular_function											owl:Class	
GO:0090291	biolink:NamedThing	negative regulation of osteoclast proliferation	Any process that decreases the rate, frequency, or extent of the multiplication or reproduction of osteoclasts, resulting in the expansion of an osteoclast cell population.	tmpzr1t_l9r_go_relaxed.owl								tb	2010-02-18T03:11:03Z					biological_process											owl:Class	
GO:0030030	biolink:NamedThing	cell projection organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a prolongation or process extending from a cell, e.g. a flagellum or axon.	tmpzr1t_l9r_go_relaxed.owl	cell surface structure organization and biogenesis|cell projection organization and biogenesis|cell projection organisation													biological_process											owl:Class	
GO:0071551	biolink:NamedThing	RIP homotypic interaction motif binding	Binding to a RIP homotypic interaction motif (RHIM) of a protein. The RHIM is a 16-amino-acid motif found in some members, including RIP3, of a family of related kinases.	tmpzr1t_l9r_go_relaxed.owl	RHIM binding							mah	2010-01-13T03:03:51Z					molecular_function											owl:Class	
GO:1904113	biolink:NamedThing	negative regulation of muscle filament sliding	Any process that stops, prevents or reduces the frequency, rate or extent of muscle filament sliding.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of muscle filament sliding|inhibition of muscle filament sliding|downregulation of muscle filament sliding|down regulation of muscle filament sliding							kmv	2015-04-03T18:40:38Z					biological_process											owl:Class	
GO:0032971	biolink:NamedThing	regulation of muscle filament sliding	Any process that modulates the frequency, rate or extent of muscle filament sliding.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0098994	biolink:NamedThing	disruption of host cell envelope during viral entry	The disruption of host cell envelope by viral proteins during virus entry.	tmpzr1t_l9r_go_relaxed.owl					VZ:3938									biological_process											owl:Class	
GO:0098933	biolink:NamedThing	disruption by symbiont of host cell envelope	The process by which a symbiont breaks down the cell wall of its host. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0046391	biolink:NamedThing	5-phosphoribose 1-diphosphate metabolic process	The chemical reactions and pathways involving 5-phosphoribose 1-diphosphate, also known as 5-phosphoribosyl-1-pyrophosphate.	tmpzr1t_l9r_go_relaxed.owl	5-phosphoribose 1-diphosphate metabolism|PRPP metabolic process				MetaCyc:PRPP-PWY									biological_process											owl:Class	
GO:1905551	biolink:NamedThing	negative regulation of protein localization to endoplasmic reticulum	Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to endoplasmic reticulum.	tmpzr1t_l9r_go_relaxed.owl	inhibition of protein localization in ER|down-regulation of protein localization in endoplasmic reticulum|down regulation of protein localization in ER|inhibition of protein localization in endoplasmic reticulum|down-regulation of protein localisation in endoplasmic reticulum|downregulation of protein localization in ER|down regulation of protein localization in endoplasmic reticulum|down regulation of protein localization to endoplasmic reticulum|negative regulation of protein localization in ER|negative regulation of protein localization in endoplasmic reticulum|downregulation of protein localization in endoplasmic reticulum|inhibition of protein localisation in endoplasmic reticulum|down-regulation of protein localization to endoplasmic reticulum|down-regulation of protein localization in ER|downregulation of protein localisation in endoplasmic reticulum|negative regulation of protein localisation in endoplasmic reticulum|inhibition of protein localization to endoplasmic reticulum|downregulation of protein localization to endoplasmic reticulum|down regulation of protein localisation in endoplasmic reticulum							rz	2016-10-12T11:37:08Z					biological_process											owl:Class	
GO:1905550	biolink:NamedThing	regulation of protein localization to endoplasmic reticulum	Any process that modulates the frequency, rate or extent of protein localization to endoplasmic reticulum.	tmpzr1t_l9r_go_relaxed.owl	regulation of protein localisation in endoplasmic reticulum|regulation of protein localization in endoplasmic reticulum|regulation of protein localization in ER							rz	2016-10-12T11:37:01Z					biological_process											owl:Class	
GO:0002480	biolink:NamedThing	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent	The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class I protein complex following intracellular transport via a pathway not requiring TAP (transporter associated with antigen processing). The peptide is typically a fragment of a larger exogenous protein which has been degraded within the cell. Class I here refers to classical class I molecules.	tmpzr1t_l9r_go_relaxed.owl	TAP-independent exogenous peptide antigen processing and presentation via MHC class I|TAP-independent antigen processing and presentation of exogenous peptide antigen via MHC class I|cross-presentation|cross presentation|exogenous peptide antigen processing and presentation via MHC class I, TAP-independent													biological_process											owl:Class	
GO:0042590	biolink:NamedThing	antigen processing and presentation of exogenous peptide antigen via MHC class I	The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class I protein complex. The peptide antigen is typically, but not always, processed from a whole protein. Class I here refers to classical class I molecules.	tmpzr1t_l9r_go_relaxed.owl	antigen presentation, exogenous antigen via major histocompatibility complex class I|exogenous peptide antigen processing and presentation via MHC class I|cross priming|cross-priming|cross-presentation|antigen presentation, exogenous antigen via MHC class I|cross presentation													biological_process											owl:Class	
GO:1990966	biolink:NamedThing	ATP generation from poly-ADP-D-ribose	The process of generating ATP in the nucleus from poly-ADP-D-ribose. Nuclear ATP generation is required for extensive chromatin remodeling events that are energy-consuming.	tmpzr1t_l9r_go_relaxed.owl								sp	2016-06-16T09:41:35Z					biological_process											owl:Class	
GO:0035870	biolink:NamedThing	dITP diphosphatase activity	Catalysis of the reaction: dITP + H2O = dIMP + diphosphate.	tmpzr1t_l9r_go_relaxed.owl	deoxyinosine triphosphate pyrophosphatase activity|2'-Deoxyinosine-5'-triphosphate pyrophosphohydrolase activity|dITP pyrophosphatase activity				RHEA:28342|Reactome:R-HSA-2509838|KEGG_REACTION:R03531|EC:3.6.1.66|MetaCyc:RXN0-1602			bf	2011-05-26T11:32:26Z					molecular_function											owl:Class	
GO:2001164	biolink:NamedThing	negative regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues	Any process that stops, prevents or reduces the frequency, rate or extent of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues.	tmpzr1t_l9r_go_relaxed.owl								se	2011-10-25T10:31:03Z					biological_process											owl:Class	
GO:0003092	biolink:NamedThing	renal water retention	The process in which renal water excretion is decreased.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of renal water excretion													biological_process											owl:Class	
GO:0035811	biolink:NamedThing	negative regulation of urine volume	Any process that decreases the amount of urine excreted from the body over a unit of time.	tmpzr1t_l9r_go_relaxed.owl	decrease in urine flow|antidiuresis|reduction of urinary volume							bf	2011-04-20T01:21:01Z					biological_process											owl:Class	
GO:0001748	biolink:NamedThing	insect visual primordium development	The process whose specific outcome is the progression of the optic placode over time, from its formation to the mature structure. During embryonic stage 12 the placode starts to invaginate, forming a pouch. Cells that will form Bolwig's organ segregate from the ventral lip of this pouch, remaining in the head epidermis. The remainder of the invagination loses contact with the outer surface and becomes the optic lobe. An example of this process is found in Drosophila melanogaster.	tmpzr1t_l9r_go_relaxed.owl	optic lobe and Bolwig's organ precursor development|optic lobe placode development|optic placode development											GO:0048049		biological_process											owl:Class	
GO:0097151	biolink:NamedThing	positive regulation of inhibitory postsynaptic potential	Any process that activates or increases the frequency, rate or extent of inhibitory postsynaptic potential (IPSP). IPSP is a temporary decrease in postsynaptic membrane potential due to the flow of negatively charged ions into the postsynaptic cell. The flow of ions that causes an IPSP is an inhibitory postsynaptic current (IPSC) and makes it more difficult for the neuron to fire an action potential.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of inhibitory post-synaptic membrane potential|positive regulation of IPSP							pr	2011-08-12T10:07:45Z					biological_process											owl:Class	
GO:0098828	biolink:NamedThing	modulation of inhibitory postsynaptic potential	Any process that modulates the frequency, rate or extent of inhibitory postsynaptic potential (IPSP). IPSP is a temporary decrease in postsynaptic membrane potential due to the flow of negatively charged ions into the postsynaptic cell. The flow of ions that causes an IPSP is an inhibitory postsynaptic current (IPSC) and makes it more difficult for the neuron to fire an action potential.	tmpzr1t_l9r_go_relaxed.owl	regulation of inhibitory postsynaptic potential													biological_process											owl:Class	
GO:0032898	biolink:NamedThing	neurotrophin production	The appearance of a neurotrophin due to biosynthesis or secretion by cells in a neuron's target field, resulting in an increase in its intracellular or extracellular levels. A neurotrophin is any of a family of growth factors that prevent apoptosis in neurons and promote nerve growth.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0042858	biolink:NamedThing	chrysobactin biosynthetic process	The chemical reactions and pathways resulting in the formation of the siderophore chrysobactin (alpha-N-(2,3-dihydroxybenzoyl)-D-lysyl-L-serine).	tmpzr1t_l9r_go_relaxed.owl	chrysobactin synthesis|chrysobactin biosynthesis|chrysobactin biosynthetic process, peptide modification|chrysobactin biosynthetic process, peptide formation|chrysobactin formation|chrysobactin anabolism											GO:0031184|GO:0031183		biological_process											owl:Class	
GO:0150031	biolink:NamedThing	regulation of protein localization to lysosome	Any process that modulates the frequency, rate or extent of protein localization to lysosome.	tmpzr1t_l9r_go_relaxed.owl								bc	2018-02-06T17:07:03Z					biological_process											owl:Class	
GO:0060341	biolink:NamedThing	regulation of cellular localization	Any process that modulates the frequency, rate or extent of a process in which a cell, a substance, or a cellular entity is transported to, or maintained in a specific location within or in the membrane of a cell.	tmpzr1t_l9r_go_relaxed.owl	regulation of cellular localisation													biological_process											owl:Class	
GO:0000813	biolink:NamedThing	ESCRT I complex	An endosomal sorting complex required for transport. It consists of the class E vacuolar protein sorting (Vps) proteins and interacts with ubiquitinated cargoes.	tmpzr1t_l9r_go_relaxed.owl	endosomal sorting complex required for transport													cellular_component											owl:Class	
GO:0036452	biolink:NamedThing	ESCRT complex	An endosomal sorting complex involved in membrane fission processes related to sorting of multivesicular bodies (MVB) in the endocytic pathway, cytokinesis and viral budding among other processes.	tmpzr1t_l9r_go_relaxed.owl	endosomal sorting complex required for transport				Wikipedia:ESCRT			bf	2013-11-06T16:25:52Z					cellular_component											owl:Class	
GO:1905168	biolink:NamedThing	positive regulation of double-strand break repair via homologous recombination	Any process that activates or increases the frequency, rate or extent of double-strand break repair via homologous recombination.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of Rad51-dependent recombinational repair|activation of homology-directed repair|up-regulation of Rad51-dependent recombinational repair|activation of double-strand break repair via homologous recombination|positive regulation of HRR|positive regulation of homology-directed repair|upregulation of double-strand break repair via homologous recombination|upregulation of Rhp51-dependent recombinational repair|up regulation of homologous recombinational repair|activation of HRR|up-regulation of double-strand break repair via homologous recombination|activation of homologous recombinational repair|up regulation of Rhp51-dependent recombinational repair|activation of Rhp51-dependent recombinational repair|positive regulation of homologous recombinational repair|up regulation of double-strand break repair via homologous recombination|up-regulation of homologous recombinational repair|upregulation of Rad51-dependent recombinational repair|upregulation of homology-directed repair|up-regulation of HRR|upregulation of HDR|activation of Rad51-dependent recombinational repair|upregulation of HRR|positive regulation of HDR|positive regulation of Rhp51-dependent recombinational repair|up-regulation of Rhp51-dependent recombinational repair|up regulation of homology-directed repair|up regulation of Rad51-dependent recombinational repair|up regulation of HDR|up-regulation of HDR|up-regulation of homology-directed repair|up regulation of HRR|activation of HDR|upregulation of homologous recombinational repair							mah	2016-04-27T12:48:47Z					biological_process											owl:Class	
GO:0010569	biolink:NamedThing	regulation of double-strand break repair via homologous recombination	Any process that modulates the frequency, rate or extent of the error-free repair of a double-strand break in DNA in which the broken DNA molecule is repaired using homologous sequences.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0071889	biolink:NamedThing	14-3-3 protein binding	Binding to a 14-3-3 protein. A 14-3-3 protein is any of a large family of approximately 30kDa acidic proteins which exist primarily as homo- and heterodimers within all eukaryotic cells, and have been implicated in the modulation of distinct biological processes by binding to specific phosphorylated sites on diverse target proteins, thereby forcing conformational changes or influencing interactions between their targets and other molecules. Each 14-3-3 protein sequence can be roughly divided into three sections: a divergent amino terminus, the conserved core region and a divergent carboxy-terminus. The conserved middle core region of the 14-3-3s encodes an amphipathic groove that forms the main functional domain, a cradle for interacting with client proteins.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-09-14T01:21:50Z					molecular_function											owl:Class	
GO:1990548	biolink:NamedThing	mitochondrial FAD transmembrane transport	The process in which FAD is transported across a mitochondrial membrane, into or out of the mitochondrion.	tmpzr1t_l9r_go_relaxed.owl								vw	2014-11-19T12:04:35Z					biological_process											owl:Class	
GO:0032872	biolink:NamedThing	regulation of stress-activated MAPK cascade	Any process that modulates the frequency, rate or extent of signal transduction mediated by the stress-activated MAPK cascade.	tmpzr1t_l9r_go_relaxed.owl	regulation of p38 MAPK signaling|regulation of stress-activated MAPKKK signalling pathway|regulation of stress-activated MAPK signalling pathway|regulation of p38 MAPK signalling|regulation of stress-activated MAPKKK cascade|regulation of stress-activated MAPK signaling pathway|regulation of stress-activated MAPKKK signaling pathway													biological_process											owl:Class	
GO:0035297	biolink:NamedThing	regulation of Malpighian tubule diameter	Ensuring that the Malpighian tubule is the correct width. Malpighian tubules have a uniform circumference along their length; the circumference of the tubes is eight cells during the time the cells are dividing, after which the cells rearrange producting tubes with a cirumference of two cells.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0035296	biolink:NamedThing	regulation of tube diameter	Any process that modulates the diameter of a tube.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0075256	biolink:NamedThing	regulation of teliospore formation	Any process that modulates the frequency, rate or extent of teliospore formation, which is the formation of a thick-walled resting or over-wintering spore produced by the rust fungi (Uredinales) and smut fungi (Ustilaginales) in which karyogamy occurs.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0043943	biolink:NamedThing	regulation of asexual sporulation resulting in formation of a cellular spore	Any process that modulates the frequency, rate or extent of the formation of a cellular spore derived from the products of mitosis.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0090407	biolink:NamedThing	organophosphate biosynthetic process	The chemical reactions and pathways resulting in the biosynthesis of deoxyribose phosphate, the phosphorylated sugar 2-deoxy-erythro-pentose.	tmpzr1t_l9r_go_relaxed.owl								tb	2011-02-26T02:22:41Z					biological_process											owl:Class	
GO:0048581	biolink:NamedThing	negative regulation of post-embryonic development	Any process that stops, prevents, or reduces the frequency, rate or extent of post-embryonic development. Post-embryonic development is defined as the process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure.	tmpzr1t_l9r_go_relaxed.owl	down regulation of post-embryonic development|down-regulation of post-embryonic development|inhibition of post-embryonic development|downregulation of post-embryonic development													biological_process											owl:Class	
GO:0098655	biolink:NamedThing	cation transmembrane transport	The process in which a cation is transported across a membrane.	tmpzr1t_l9r_go_relaxed.owl	ATP hydrolysis coupled cation transmembrane transport											GO:0099132		biological_process											owl:Class	
GO:0032802	biolink:NamedThing	low-density lipoprotein particle receptor catabolic process	The chemical reactions and pathways resulting in the breakdown of a low-density lipoprotein particle receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.	tmpzr1t_l9r_go_relaxed.owl	low-density lipoprotein receptor catabolic process|LDL receptor degradation|low-density lipoprotein receptor breakdown|LDL receptor catabolism|LDL receptor breakdown|LDL receptor catabolic process|low-density lipoprotein receptor catabolism|low-density lipoprotein receptor degradation													biological_process											owl:Class	
GO:0032801	biolink:NamedThing	receptor catabolic process	The chemical reactions and pathways resulting in the breakdown of a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.	tmpzr1t_l9r_go_relaxed.owl	receptor catabolism|receptor breakdown|receptor degradation													biological_process											owl:Class	
GO:0032237	biolink:NamedThing	activation of store-operated calcium channel activity	A process that initiates the activity of an inactive store-operated calcium channel.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1901341	biolink:NamedThing	positive regulation of store-operated calcium channel activity	Any process that activates or increases the frequency, rate or extent of store-operated calcium channel activity.	tmpzr1t_l9r_go_relaxed.owl	activation of store-operated calcium channel activity|upregulation of store-operated calcium channel activity|up-regulation of store-operated calcium channel activity|up regulation of store-operated calcium channel activity							pr	2012-09-03T14:24:38Z					biological_process											owl:Class	
GO:1905289	biolink:NamedThing	regulation of CAMKK-AMPK signaling cascade	Any process that modulates the frequency, rate or extent of CAMKK-AMPK signaling cascade.	tmpzr1t_l9r_go_relaxed.owl	regulation of stress-activated AMP-activated protein kinase signaling cascade							sl	2016-06-23T20:36:55Z					biological_process											owl:Class	
GO:0047632	biolink:NamedThing	agmatine deiminase activity	Catalysis of the reaction: agmatine + H2O = N-carbamoylputrescine + NH3.	tmpzr1t_l9r_go_relaxed.owl	agmatine iminohydrolase activity|agmatine amidinohydrolase				EC:3.5.3.12|MetaCyc:AGMATINE-DEIMINASE-RXN|RHEA:18037									molecular_function											owl:Class	
GO:0016813	biolink:NamedThing	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines	Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a linear amidine, a compound of the form R-C(=NH)-NH2.	tmpzr1t_l9r_go_relaxed.owl					EC:3.5.3.-									molecular_function											owl:Class	
GO:0039611	biolink:NamedThing	suppression by virus of host translation initiation factor activity	Any process in which a virus prevents or reduces the frequency, rate or extent of activity of a host translation initiation factor.	tmpzr1t_l9r_go_relaxed.owl	inhibition of activity of host translation initiation factor|inactivation of eIF2 activity|Inhibition of host translation factors by virus|suppression by virus of host EIF-4E activity							bf	2012-07-06T10:27:16Z					biological_process											owl:Class	
GO:0120179	biolink:NamedThing	adherens junction disassembly	The disaggregation of an adherens junction into its constituent components. An adherens junction is a cell-cell junction composed of the epithelial cadherin-catenin complex at which the cytoplasmic face of the plasma membrane is attached to actin filaments.	tmpzr1t_l9r_go_relaxed.owl								krc	2018-07-12T17:29:56Z					biological_process											owl:Class	
GO:0150147	biolink:NamedThing	cell-cell junction disassembly	The disaggregation of a cell-cell junction into its constituent components.	tmpzr1t_l9r_go_relaxed.owl								bc	2019-12-08T11:16:14Z					biological_process											owl:Class	
GO:0052790	biolink:NamedThing	chitooligosaccharide deacetylase activity	Catalysis of the reaction: chitooligosaccharide with N-acetylglucosamine at nonreducing terminal + H2O = chitooligosaccharide with glucosamine at nonreducing terminal + acetate. This reaction is the deacetylation of a chitooligosaccharide at the nonreducing N-acetylglucosamine residue; chitooligosaccharide are composed of (1->4)-linked D-glucosamine (GlcN) and N-acetyl-D-glucosamine (GlcNAc) in varying proportions.	tmpzr1t_l9r_go_relaxed.owl					EC:3.5.1.-			ai	2011-10-04T03:48:35Z					molecular_function											owl:Class	
GO:0010106	biolink:NamedThing	cellular response to iron ion starvation	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of iron ions.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0061934	biolink:NamedThing	regulation of adenine biosynthetic process	Any process that modulates the frequency, rate or extent of an adenine biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl								dph	2017-09-05T14:58:46Z					biological_process											owl:Class	
GO:0086043	biolink:NamedThing	bundle of His cell action potential	An action potential that occurs in a bundle of His cell.	tmpzr1t_l9r_go_relaxed.owl	bundle of His cardiac muscle cell action potential							dph	2011-11-15T12:01:18Z					biological_process											owl:Class	
GO:0086001	biolink:NamedThing	cardiac muscle cell action potential	An action potential that occurs in a cardiac muscle cell.	tmpzr1t_l9r_go_relaxed.owl								tb	2011-11-10T07:45:11Z					biological_process											owl:Class	
GO:0070539	biolink:NamedThing	linoleic acid binding	Binding to linoleic acid, the 18-carbon unsaturated fatty acid (9Z,12Z)-octadeca-9,12-dienoic acid.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0061128	biolink:NamedThing	positive regulation of chemotaxis to cAMP by DIF-2	Any process that increases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of DIF-2. DIF-2 is a chlorinated alkylphenone.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-05-17T08:48:17Z					biological_process											owl:Class	
GO:0061124	biolink:NamedThing	positive regulation of positive chemotaxis to cAMP by chlorinated alkylphenone	Any process that increases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of a chlorinated alkylphenone. An alkylphenone is an aromatic polyketide with methyl and chlorine substitutions.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-05-17T08:33:40Z					biological_process											owl:Class	
GO:1904082	biolink:NamedThing	pyrimidine nucleobase transmembrane transport	The process in which pyrimidine is transported across a membrane.	tmpzr1t_l9r_go_relaxed.owl								tb	2015-03-25T00:13:16Z					biological_process											owl:Class	
GO:0015855	biolink:NamedThing	pyrimidine nucleobase transport	The directed movement of pyrimidine nucleobases, one of the two classes of nitrogen-containing ring compounds found in DNA and RNA, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	pyrimidine transport|pyrimidine transmembrane transport|pyrimidine base transport|pyrimidine base transmembrane transport													biological_process											owl:Class	
GO:1900259	biolink:NamedThing	regulation of RNA-directed 5'-3' RNA polymerase activity	Any process that modulates the frequency, rate or extent of RNA-directed 5'-3' RNA polymerase activity.	tmpzr1t_l9r_go_relaxed.owl	regulation of ribonucleic synthetase activity|regulation of RDRP|regulation of ribonucleic acid replicase activity|regulation of RNA replicase activity|regulation of RNA-dependent RNA replicase activity|regulation of RNA synthetase activity|regulation of RNA-dependent RNA polymerase activity|regulation of 3D polymerase activity|regulation of RNA nucleotidyltransferase (RNA-directed) activity|regulation of RNA-directed RNA polymerase activity|regulation of ribonucleic acid-dependent ribonucleate nucleotidyltransferase activity|regulation of Q-beta replicase activity|regulation of polymerase L|regulation of PB1 proteins|regulation of ribonucleic acid-dependent ribonucleic acid polymerase activity|regulation of PB2 proteins|regulation of RNA-dependent ribonucleate nucleotidyltransferase activity|regulation of nucleoside-triphosphate:RNA nucleotidyltransferase (RNA-directed)|regulation of transcriptase|regulation of ribonucleic replicase activity|regulation of phage f2 replicase							tb	2012-04-03T11:01:53Z					biological_process											owl:Class	
GO:0051338	biolink:NamedThing	regulation of transferase activity	Any process that modulates the frequency, rate or extent of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2.	tmpzr1t_l9r_go_relaxed.owl	transferase regulator					This term is useful for grouping, but is too general for manual annotation. Please use a child term instead.								biological_process											owl:Class	
GO:0010323	biolink:NamedThing	negative regulation of isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of isopentenyl diphosphate produced via the methylerythritol (MEP) pathway (mevalonate-independent).	tmpzr1t_l9r_go_relaxed.owl	down regulation of isopentenyl diphosphate biosynthetic process, mevalonate-independent pathway|inhibition of isopentenyl diphosphate biosynthetic process, mevalonate-independent pathway|down-regulation of isopentenyl diphosphate biosynthetic process, mevalonate-independent pathway|negative regulation of isopentenyl diphosphate biosynthetic process, mevalonate-independent pathway|downregulation of isopentenyl diphosphate biosynthetic process, mevalonate-independent pathway													biological_process											owl:Class	
GO:0019212	biolink:NamedThing	phosphatase inhibitor activity	Binds to and stops, prevents or reduces the activity of a phosphatase, an enzyme which catalyzes of the removal of a phosphate group from a substrate molecule.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:2000993	biolink:NamedThing	positive regulation of galactomannan catabolic process	Any process that activates or increases the frequency, rate or extent of galactomannan catabolic process.	tmpzr1t_l9r_go_relaxed.owl								tt	2011-08-08T03:16:07Z					biological_process											owl:Class	
GO:0006884	biolink:NamedThing	cell volume homeostasis	Any process involved in maintaining the steady state of a cell's volume. The cell's volume refers to the three-dimensional space occupied by a cell.	tmpzr1t_l9r_go_relaxed.owl	regulation of cell volume													biological_process											owl:Class	
GO:0019725	biolink:NamedThing	cellular homeostasis	Any process involved in the maintenance of an internal steady state at the level of the cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0045337	biolink:NamedThing	farnesyl diphosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of farnesyl diphosphate.	tmpzr1t_l9r_go_relaxed.owl	farnesyl diphosphate biosynthesis|farnesyl diphosphate formation|farnesyl diphosphate anabolism|farnesyl diphosphate synthesis				MetaCyc:PWY-5123									biological_process											owl:Class	
GO:0008654	biolink:NamedThing	phospholipid biosynthetic process	The chemical reactions and pathways resulting in the formation of a phospholipid, a lipid containing phosphoric acid as a mono- or diester.	tmpzr1t_l9r_go_relaxed.owl	phospholipid anabolism|phospholipid formation|phospholipid synthesis|phospholipid biosynthesis				MetaCyc:PHOSLIPSYN2-PWY|MetaCyc:PHOSLIPSYN-PWY|MetaCyc:LIPASYN-PWY									biological_process											owl:Class	
GO:1902846	biolink:NamedThing	positive regulation of mitotic spindle elongation	Any process that activates or increases the frequency, rate or extent of mitotic spindle elongation.	tmpzr1t_l9r_go_relaxed.owl	upregulation of mitotic spindle elongation|up-regulation of mitotic spindle elongation|up regulation of mitotic spindle elongation|positive regulation of spindle elongation during mitosis|upregulation of spindle elongation during mitosis|up-regulation of spindle elongation during mitosis|activation of spindle elongation during mitosis|activation of mitotic spindle elongation|up regulation of spindle elongation during mitosis							vw	2014-04-02T08:43:34Z					biological_process											owl:Class	
GO:0032888	biolink:NamedThing	regulation of mitotic spindle elongation	Any process that modulates the frequency, rate or extent of the cell cycle process in which the distance is lengthened between poles of the mitotic spindle.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0051888	biolink:NamedThing	positive regulation of timing of exogen	Any process that activates or increases the frequency, rate or extent of timing of exogen, the shedding phase of the hair cycle.	tmpzr1t_l9r_go_relaxed.owl	stimulation of exogen|up-regulation of exogen|upregulation of exogen|positive regulation of exogen|activation of exogen|up regulation of exogen													biological_process											owl:Class	
GO:0048818	biolink:NamedThing	positive regulation of hair follicle maturation	Any process that activates or increases the frequency, rate or extent of hair follicle maturation.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of hair follicle maturation|upregulation of hair follicle maturation|activation of hair follicle maturation|stimulation of hair follicle maturation|up regulation of hair follicle maturation													biological_process											owl:Class	
GO:1900069	biolink:NamedThing	regulation of cellular hyperosmotic salinity response	Any process that modulates the frequency, rate or extent of cellular hyperosmotic salinity response.	tmpzr1t_l9r_go_relaxed.owl	regulation of cellular response to hyperosmotic salt stress							pr	2012-01-26T02:45:39Z					biological_process											owl:Class	
GO:1901000	biolink:NamedThing	regulation of response to salt stress	Any process that modulates the frequency, rate or extent of response to salt stress.	tmpzr1t_l9r_go_relaxed.owl	regulation of salinity response|regulation of response to ionic osmotic stress							dhl	2012-06-14T05:41:19Z					biological_process											owl:Class	
GO:0010753	biolink:NamedThing	positive regulation of cGMP-mediated signaling	Any process that increases the rate, frequency or extent of cGMP-mediated signaling. cGMP-mediated signaling is a series of molecular signals in which a cell uses cyclic GMP to convert an extracellular signal into a response.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of cGMP-mediated signalling													biological_process											owl:Class	
GO:0044619	biolink:NamedThing	positive regulation of relaxation of uterine smooth muscle in other organism	The process in which an organism increases the extent of relaxation of smooth muscle in the uterus of a second organism.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-07-04T02:51:26Z					biological_process											owl:Class	
GO:0044618	biolink:NamedThing	modulation of relaxation of uterine smooth muscle in other organism	The process in which an organism effects a change in the relaxation of smooth muscle in the uterus of a second organism.	tmpzr1t_l9r_go_relaxed.owl	regulation of relaxation of uterine smooth muscle in other organism							jl	2012-07-04T01:56:04Z					biological_process											owl:Class	
GO:0061713	biolink:NamedThing	anterior neural tube closure	The step in the formation of the neural tube, where the paired anterior neural folds are brought together and fuse at the dorsal midline.	tmpzr1t_l9r_go_relaxed.owl								dph	2015-06-23T10:13:41Z					biological_process											owl:Class	
GO:0060606	biolink:NamedThing	tube closure	Creation of the central hole of a tube in an anatomical structure by sealing the edges of an epithelial fold.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-05-15T09:44:07Z					biological_process											owl:Class	
GO:0062042	biolink:NamedThing	regulation of cardiac epithelial to mesenchymal transition	Any process that modulates the rate, frequency or extent of cardiac epithelial to mesenchymal transition, a transition where a cardiac epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell.	tmpzr1t_l9r_go_relaxed.owl								dph	2018-05-10T18:09:31Z					biological_process											owl:Class	
GO:0019380	biolink:NamedThing	3-phenylpropionate catabolic process	The chemical reactions and pathways resulting in the breakdown of 3-phenylpropionate, the anion of phenylpropanoic acid.	tmpzr1t_l9r_go_relaxed.owl	3-phenylpropionate degradation|3-phenylpropionate catabolism|3-phenylpropionate breakdown				MetaCyc:P281-PWY|MetaCyc:HCAMHPDEG-PWY									biological_process											owl:Class	
GO:0045608	biolink:NamedThing	negative regulation of inner ear auditory receptor cell differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of auditory hair cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of auditory receptor cell differentiation|negative regulation of auditory receptor cell differentiation|negative regulation of auditory hair cell differentiation|inhibition of auditory receptor cell differentiation|down regulation of auditory receptor cell differentiation|downregulation of auditory receptor cell differentiation													biological_process											owl:Class	
GO:0045607	biolink:NamedThing	regulation of inner ear auditory receptor cell differentiation	Any process that modulates the frequency, rate or extent of auditory hair cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	regulation of auditory hair cell differentiation|regulation of auditory receptor cell differentiation													biological_process											owl:Class	
GO:0061350	biolink:NamedThing	planar cell polarity pathway involved in cardiac muscle tissue morphogenesis	The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors including C-Jun N-terminal kinase (JNK) to modulate cytoskeletal elements and control cell polarity that contributes to the shaping of the cardiac muscle tissue.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-10-01T10:57:33Z					biological_process											owl:Class	
GO:0099187	biolink:NamedThing	presynaptic cytoskeleton organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures and their associated proteins in the presynaptic cytoskeleton.	tmpzr1t_l9r_go_relaxed.owl								dos	2017-12-20T15:05:34Z					biological_process											owl:Class	
GO:0007010	biolink:NamedThing	cytoskeleton organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures.	tmpzr1t_l9r_go_relaxed.owl	cytoskeletal organization and biogenesis|cytoskeleton organization and biogenesis|cytoskeleton organisation|cytoskeletal regulator activity													biological_process											owl:Class	
GO:0097380	biolink:NamedThing	dorsal spinal cord interneuron anterior axon guidance	The process in which the migration of an axon growth cone of a dorsal spinal cord interneuron is directed to a specific target site in the anterior direction along the anterior-posterior body axis in response to a combination of attractive and repulsive cues. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism.	tmpzr1t_l9r_go_relaxed.owl	dorsal interneuron rostral axon projection							pr	2012-10-01T10:24:41Z					biological_process											owl:Class	
GO:0033564	biolink:NamedThing	anterior/posterior axon guidance	The process in which the migration of an axon growth cone is directed to a specific target site along the anterior-posterior body axis in response to a combination of attractive and repulsive cues. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism.	tmpzr1t_l9r_go_relaxed.owl	anterior/posterior axon pathfinding|anterior-posterior axon guidance													biological_process											owl:Class	
GO:2000409	biolink:NamedThing	positive regulation of T cell extravasation	Any process that activates or increases the frequency, rate or extent of T cell extravasation.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of T lymphocyte extravasation|positive regulation of T-lymphocyte extravasation|positive regulation of T-cell extravasation							mah	2011-02-23T10:52:50Z					biological_process											owl:Class	
GO:2000407	biolink:NamedThing	regulation of T cell extravasation	Any process that modulates the frequency, rate or extent of T cell extravasation.	tmpzr1t_l9r_go_relaxed.owl	regulation of T lymphocyte extravasation|regulation of T-cell extravasation|regulation of T-lymphocyte extravasation							mah	2011-02-23T10:51:58Z					biological_process											owl:Class	
GO:0052923	biolink:NamedThing	all-trans-nonaprenyl-diphosphate synthase (geranyl-diphosphate specific) activity	Catalysis of the reaction: geranyl diphosphate + 7 isopentenyl diphosphate = 7 diphosphate + all-trans-nonaprenyl diphosphate.	tmpzr1t_l9r_go_relaxed.owl	nonaprenyl diphosphate synthase activity|solanesyl diphosphate synthetase activity|solPP synthase activity|SPP-synthase activity|SPP synthase activity|solanesyl-diphosphate synthase activity				MetaCyc:TRANS-OCTAPRENYLTRANSTRANSFERASE-RXN|KEGG_REACTION:R09250|RHEA:27563|EC:2.5.1.84									molecular_function											owl:Class	
GO:0003264	biolink:NamedThing	regulation of cardioblast proliferation	Any process that modulates the frequency, rate or extent of cardioblast proliferation. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-10-15T02:19:37Z					biological_process											owl:Class	
GO:2000136	biolink:NamedThing	regulation of cell proliferation involved in heart morphogenesis	Any process that modulates the frequency, rate or extent of cell proliferation involved in heart morphogenesis.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-09-29T12:43:53Z					biological_process											owl:Class	
GO:1903619	biolink:NamedThing	negative regulation of transdifferentiation	Any process that stops, prevents or reduces the frequency, rate or extent of transdifferentiation.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of transdifferentiation|inhibition of transdifferentiation|downregulation of transdifferentiation|down regulation of transdifferentiation							jl	2014-11-19T11:25:05Z					biological_process											owl:Class	
GO:0016076	biolink:NamedThing	snRNA catabolic process	The chemical reactions and pathways resulting in the breakdown of snRNA, small nuclear RNA, low-molecular-mass RNA molecules found in the eukaryotic nucleus as components of the small nuclear ribonucleoprotein.	tmpzr1t_l9r_go_relaxed.owl	snRNA breakdown|snRNA catabolism|snRNA degradation													biological_process											owl:Class	
GO:0016073	biolink:NamedThing	snRNA metabolic process	The chemical reactions and pathways involving snRNA, small nuclear RNA, any of various low-molecular-mass RNA molecules found in the eukaryotic nucleus as components of the small nuclear ribonucleoprotein.	tmpzr1t_l9r_go_relaxed.owl	snRNA metabolism													biological_process											owl:Class	
GO:0030239	biolink:NamedThing	myofibril assembly	Formation of myofibrils, the repeating units of striated muscle.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0071040	biolink:NamedThing	nuclear polyadenylation-dependent antisense transcript catabolic process	The chemical reactions and pathways occurring in the nucleus and resulting in the breakdown of an antisense transcript, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target antisense transcript.	tmpzr1t_l9r_go_relaxed.owl	nuclear poly(A)-dependent antisense transcript catabolic process							krc	2009-07-29T01:25:21Z					biological_process											owl:Class	
GO:0071046	biolink:NamedThing	nuclear polyadenylation-dependent ncRNA catabolic process	The chemical reactions and pathways occurring in the nucleus and resulting in the breakdown of a noncoding RNA (ncRNA) molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target ncRNA.	tmpzr1t_l9r_go_relaxed.owl	nuclear poly(A)-dependent ncRNA catabolic process							krc	2009-08-06T02:14:53Z					biological_process											owl:Class	
GO:1902692	biolink:NamedThing	regulation of neuroblast proliferation	Any process that modulates the frequency, rate or extent of neuroblast proliferation.	tmpzr1t_l9r_go_relaxed.owl								rl	2014-02-18T10:03:31Z					biological_process											owl:Class	
GO:1900378	biolink:NamedThing	positive regulation of secondary metabolite biosynthetic process	Any process that activates or increases the frequency, rate or extent of secondary metabolite biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	activation of secondary metabolite biosynthetic process|activation of secondary metabolite biosynthesis|upregulation of secondary metabolite biosynthetic process|up-regulation of secondary metabolite biosynthesis|up regulation of secondary metabolite biosynthesis|positive regulation of secondary metabolite biosynthesis|up-regulation of secondary metabolite biosynthetic process|upregulation of secondary metabolite biosynthesis|up regulation of secondary metabolite biosynthetic process							di	2012-04-17T01:55:41Z					biological_process											owl:Class	
GO:0017199	biolink:NamedThing	N-terminal peptidyl-threonine acetylation	The acetylation of the N-terminal threonine of proteins to form the derivative N-acetyl-L-threonine; catalyzed by peptide alpha-N-acetyltransferase.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0052	See also the molecular function term 'peptide alpha-N-acetyltransferase activity ; GO:0004596'.								biological_process											owl:Class	
GO:0120257	biolink:NamedThing	peptidyl-threonine acetylation	The acetylation of peptidyl-threonine.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/19957						krc	2020-09-08T18:01:01Z					biological_process											owl:Class	
GO:2000187	biolink:NamedThing	positive regulation of phosphate transmembrane transport	Any process that activates or increases the frequency, rate or extent of phosphate transmembrane transport.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of phosphate membrane transport							vw	2010-10-15T11:33:10Z					biological_process											owl:Class	
GO:1903797	biolink:NamedThing	positive regulation of inorganic anion transmembrane transport	Any process that activates or increases the frequency, rate or extent of inorganic anion transmembrane transport.	tmpzr1t_l9r_go_relaxed.owl	up regulation of inorganic anion membrane transport|upregulation of inorganic anion membrane transport|activation of inorganic anion membrane transport|up regulation of transmembrane inorganic anion transport|up-regulation of inorganic anion transmembrane transport|up-regulation of transmembrane inorganic anion transport|activation of transmembrane inorganic anion transport|positive regulation of transmembrane inorganic anion transport|upregulation of inorganic anion transmembrane transport|positive regulation of inorganic anion membrane transport|activation of inorganic anion transmembrane transport|upregulation of transmembrane inorganic anion transport|up regulation of inorganic anion transmembrane transport|up-regulation of inorganic anion membrane transport							sl	2015-01-14T21:45:08Z					biological_process											owl:Class	
GO:0015985	biolink:NamedThing	energy coupled proton transport, down electrochemical gradient	The transport of protons across a membrane to generate an electrochemical gradient (proton-motive force) that provides energy for the synthesis of ATP or GTP.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1902600	biolink:NamedThing	proton transmembrane transport	The directed movement of a proton across a membrane.	tmpzr1t_l9r_go_relaxed.owl	passive proton transport, down the electrochemical gradient|hydrogen ion transport|hydrogen transport|proton transport|hydrogen ion transmembrane transport|ATP hydrolysis coupled proton transport|hydrogen transmembrane transport							pr	2013-12-20T11:08:37Z			GO:0015992|GO:0006818|GO:0015991		biological_process											owl:Class	
GO:0019583	biolink:NamedThing	galactonate metabolic process	The chemical reactions and pathways involving galactonate, the anion of galactonic acid, an organic acid derived from the sugar galactose.	tmpzr1t_l9r_go_relaxed.owl	galactonate metabolism													biological_process											owl:Class	
GO:0019520	biolink:NamedThing	aldonic acid metabolic process	The chemical reactions and pathways involving aldonic acid, a monocarboxylic acid with a chain of three or more carbon atoms, derived from an aldose by oxidation of the aldehydic group.	tmpzr1t_l9r_go_relaxed.owl	aldonic acid metabolism													biological_process											owl:Class	
GO:0035891	biolink:NamedThing	exit from host cell	The directed movement of an organism out of a cell of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	ejection from host cell|host cell exit							bf	2011-06-15T02:09:28Z					biological_process											owl:Class	
GO:0035890	biolink:NamedThing	exit from host	The directed movement of an organism out of the body, tissues or cells of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	ejection from host							bf	2011-06-15T02:08:03Z					biological_process											owl:Class	
GO:0050549	biolink:NamedThing	cyclohexyl-isocyanide hydratase activity	Catalysis of the reaction: N-cyclohexylformamide + H(+) = cyclohexyl isocyanide + H(2)O.	tmpzr1t_l9r_go_relaxed.owl	N-cyclohexylformamide hydro-lyase (cyclohexyl-isocyanide-forming)|N-cyclohexylformamide hydro-lyase activity|isonitrile hydratase activity				EC:4.2.1.103|KEGG_REACTION:R05771|UM-BBD_reactionID:r1029|MetaCyc:4.2.1.103-RXN|RHEA:18197									molecular_function											owl:Class	
GO:0004772	biolink:NamedThing	sterol O-acyltransferase activity	Catalysis of the reaction: acyl-CoA + a sterol = CoA + a sterol ester.	tmpzr1t_l9r_go_relaxed.owl	sterol-ester synthetase activity|sterol-ester synthase activity											GO:0017066		molecular_function											owl:Class	
GO:1900954	biolink:NamedThing	negative regulation of 18-methylnonadec-1-ene metabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of 18-methylnonadec-1-ene metabolic process.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of 18-methylnonadec-1-ene metabolism|downregulation of 18-methylnonadec-1-ene metabolism|down regulation of 18-methylnonadec-1-ene metabolic process|downregulation of 18-methylnonadec-1-ene metabolic process|down regulation of 18-methylnonadec-1-ene metabolism|inhibition of 18-methylnonadec-1-ene metabolic process|inhibition of 18-methylnonadec-1-ene metabolism|down-regulation of 18-methylnonadec-1-ene metabolism|down-regulation of 18-methylnonadec-1-ene metabolic process							tt	2012-06-14T03:25:37Z					biological_process											owl:Class	
GO:1900953	biolink:NamedThing	regulation of 18-methylnonadec-1-ene metabolic process	Any process that modulates the frequency, rate or extent of 18-methylnonadec-1-ene metabolic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of 18-methylnonadec-1-ene metabolism							tt	2012-06-14T03:25:16Z					biological_process											owl:Class	
GO:0042341	biolink:NamedThing	cyanogenic glycoside metabolic process	The chemical reactions and pathways involving cyanogenic glycosides, any glycoside containing a cyano group that is released as hydrocyanic acid on acid hydrolysis; such compounds occur in the kernels of various fruits.	tmpzr1t_l9r_go_relaxed.owl	cyanogenic glycoside metabolism													biological_process											owl:Class	
GO:0050513	biolink:NamedThing	glycoprotein 2-beta-D-xylosyltransferase activity	Catalysis of the reaction: N(4)-{N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->6)]-beta-D-mannosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl}-L-asparagine + UDP-alpha-D-xylose = N(4)-{N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->6)]-[beta-D-xylosyl-(1->2)]-beta-D-mannosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl}-L-asparagine + H(+) + UDP.	tmpzr1t_l9r_go_relaxed.owl	1,2-beta-xylosyltransferase activity|beta-1,2-xylosyltransferase activity|glycoprotein 2-b-D-xylosyltransferase activity				EC:2.4.2.38|RHEA:10612|KEGG_REACTION:R06016|MetaCyc:2.4.2.38-RXN									molecular_function											owl:Class	
GO:0035252	biolink:NamedThing	UDP-xylosyltransferase activity	Catalysis of the transfer of a xylosyl group from UDP-xylose to an acceptor molecule.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-5617138|Reactome:R-HSA-6785668|Reactome:R-HSA-9638090									molecular_function											owl:Class	
GO:0009806	biolink:NamedThing	lignan metabolic process	The chemical reactions and pathways involving lignans, any member of a class of plant metabolites related to lignins. Lignans are usually found as phenylpropanoid dimers in which the phenylpropanoid units are linked tail to tail and thus having a 2,3 dibenzylbutane skeleton, but higher oligomers can also exist.	tmpzr1t_l9r_go_relaxed.owl	lignan metabolism													biological_process											owl:Class	
GO:0009698	biolink:NamedThing	phenylpropanoid metabolic process	The chemical reactions and pathways involving aromatic derivatives of trans-cinnamic acid.	tmpzr1t_l9r_go_relaxed.owl	phenylpropanoid metabolism				MetaCyc:PWY1F-467									biological_process											owl:Class	
GO:1903512	biolink:NamedThing	phytanic acid metabolic process	The chemical reactions and pathways involving phytanic acid.	tmpzr1t_l9r_go_relaxed.owl	phytanic acid metabolism							dph	2014-10-01T22:00:29Z					biological_process											owl:Class	
GO:0097089	biolink:NamedThing	methyl-branched fatty acid metabolic process	The chemical reactions and pathways involving methyl-branched fatty acids, aliphatic monocarboxylic acids with methyl branches on the main chain.	tmpzr1t_l9r_go_relaxed.owl	methyl-branched fatty acid metabolism							pr	2011-07-01T01:06:15Z					biological_process											owl:Class	
GO:1902991	biolink:NamedThing	regulation of amyloid precursor protein catabolic process	Any process that modulates the frequency, rate or extent of amyloid precursor protein catabolic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of APP catabolism|regulation of amyloid precursor protein catabolism|regulation of amyloid precursor protein degradation|regulation of APP catabolic process|regulation of amyloid precursor protein breakdown					An example of this is human FKBP1A/12 (UniProt symbol P62942) in PMID:24499793 (inferred from direct assay).		rl	2014-05-08T14:21:04Z					biological_process											owl:Class	
GO:0018518	biolink:NamedThing	5,6-dihydroxy-3-methyl-2-oxo-1,2,5,6-tetrahydroquinoline dehydrogenase activity	Catalysis of the reaction: 5,6-dihydroxy-3-methyl-5,6-dihydroquinolin-2(1H)-one + NAD(+) = 5,6-dihydroxy-3-methyl-2-oxo-1,2-dihydroquinoline + H(+) + NADH.	tmpzr1t_l9r_go_relaxed.owl	5,6-dihydrodiol-3-methyl-2-oxo-1,2-dihydroquinoline dehydrogenase|5,6-dihydroxy-3-methyl-2-oxo-1,2,5,6-tetrahydroquinoline:NAD+ oxidoreductase activity				EC:1.3.1.65|RHEA:24556|UM-BBD_reactionID:r0053|KEGG_REACTION:R05312|MetaCyc:RXN-643									molecular_function											owl:Class	
GO:0071243	biolink:NamedThing	cellular response to arsenic-containing substance	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an arsenic stimulus from compounds containing arsenic, including arsenates, arsenites, and arsenides.	tmpzr1t_l9r_go_relaxed.owl	cellular response to arsenic							mah	2009-12-03T02:41:05Z					biological_process											owl:Class	
GO:0046685	biolink:NamedThing	response to arsenic-containing substance	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an arsenic stimulus from compounds containing arsenic, including arsenates, arsenites, and arsenides.	tmpzr1t_l9r_go_relaxed.owl	arsenate sensitivity/resistance|response to arsenic													biological_process											owl:Class	
GO:0048884	biolink:NamedThing	neuromast development	The process whose specific outcome is the progression of the neuromast over time, from its formation to the mature structure. The neuromast is the sensory organ of the lateral line and is composed of a population of sensory hair cells, and nonsensory supporting cells and mantle cells. Neuromasts are located superficially on the epithelium or in lateral line canals.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0008704	biolink:NamedThing	5-carboxymethyl-2-hydroxymuconate delta-isomerase activity	Catalysis of the reaction: 5-carboxymethyl-2-hydroxymuconate = 5-carboxy-2-oxohept-3-enedioate.	tmpzr1t_l9r_go_relaxed.owl	CHM isomerase activity|hpaG1|HHDD isomerase activity|hpaG-1|5-carboxymethyl-2-hydroxymuconic acid isomerase activity|5-carboxymethyl-2-hydroxymuconate D-isomerase activity|2-hydroxyhepta-2,4-diene-1,7-dioate isomerase|5-carboxymethyl-2-hydroxymuconate delta2,Delta4-2-oxo,Delta3-isomerase activity				RHEA:18813|MetaCyc:5.3.3.10-RXN|EC:5.3.3.10|UM-BBD_reactionID:r0366							GO:0018843		molecular_function											owl:Class	
GO:0016863	biolink:NamedThing	intramolecular oxidoreductase activity, transposing C=C bonds	Catalysis of an oxidation-reduction (redox) reaction in which the hydrogen donor and acceptor are the same molecule, one or more carbon-carbon double bonds in the molecule are rearranged, and no oxidized product appears.	tmpzr1t_l9r_go_relaxed.owl	intramolecular isomerase activity, transposing C=C bonds				EC:5.3.3.-									molecular_function											owl:Class	
GO:0009893	biolink:NamedThing	positive regulation of metabolic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of organismal metabolism|upregulation of metabolic process|activation of metabolic process|up-regulation of organismal metabolic process|up regulation of metabolic process|stimulation of metabolic process|stimulation of organismal metabolic process|positive regulation of metabolism|up-regulation of metabolic process|positive regulation of multicellular organismal metabolic process											GO:0044253		biological_process											owl:Class	
GO:0060414	biolink:NamedThing	aorta smooth muscle tissue morphogenesis	The process in which the structure of the smooth muscle tissue surrounding the aorta is generated and organized. An aorta is an artery that carries blood from the heart to other parts of the body.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0060415	biolink:NamedThing	muscle tissue morphogenesis	The process in which the anatomical structures of muscle tissue are generated and organized. Muscle tissue consists of a set of cells that are part of an organ and carry out a contractive function.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0008983	biolink:NamedThing	protein-glutamate O-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + protein L-glutamate = S-adenosyl-L-homocysteine + protein L-glutamate 5-methyl ester; this reaction is the methylation of peptidyl-L-glutamate to form peptidyl-L-glutamate 5-methyl ester.	tmpzr1t_l9r_go_relaxed.owl	protein methylase II|S-adenosyl-L-methionine:protein-L-glutamate O-methyltransferase activity|methyl-accepting chemotaxis protein O-methyltransferase activity|S-adenosylmethionine:protein-carboxyl O-methyltransferase activity|protein carboxylmethyltransferase II|protein(carboxyl)methyltransferase activity|protein carboxymethyltransferase activity|protein O-methyltransferase activity|S-adenosylmethionine-glutamyl methyltransferase activity|protein(aspartate)methyltransferase activity|protein carboxyl-O-methyltransferase activity|protein carboxyl-methylase activity|MCP methyltransferase II|protein carboxymethylase activity|MCP methyltransferase I|methyl-accepting chemotaxis protein methyltransferase II				RESID:AA0072|EC:2.1.1.80|RHEA:24452|MetaCyc:CHER-RXN									molecular_function											owl:Class	
GO:0046704	biolink:NamedThing	CDP metabolic process	The chemical reactions and pathways involving CDP, cytidine (5'-)diphosphate.	tmpzr1t_l9r_go_relaxed.owl	CDP metabolism													biological_process											owl:Class	
GO:0006723	biolink:NamedThing	cuticle hydrocarbon biosynthetic process	The chemical reactions and pathways resulting in the formation of hydrocarbons that make up the cuticle, the outer layer of some animals and plants, which acts to prevent water loss.	tmpzr1t_l9r_go_relaxed.owl	cuticle hydrocarbon synthesis|cuticle hydrocarbon anabolism|cuticle hydrocarbon biosynthesis|cuticle hydrocarbon formation													biological_process											owl:Class	
GO:0120251	biolink:NamedThing	hydrocarbon biosynthetic process	The chemical reactions and pathways resulting in the formation of a hydrocarbon, a compound consisting of carbon and hydrogen only.	tmpzr1t_l9r_go_relaxed.owl	hydrocarbon formation|hydrocarbon anabolism|hydrocarbon biosynthesis|hydrocarbon synthesis	https://github.com/geneontology/go-ontology/issues/19842						krc	2020-09-02T20:35:53Z					biological_process											owl:Class	
GO:0102143	biolink:NamedThing	carboxynorspermidine dehydrogenase I activity	Catalysis of the reaction: carboxynorspermidine + NADP + H2O <=> L-aspartic acid 4-semialdehyde betaine + trimethylenediaminium + NADPH + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-11565|RHEA:34115									molecular_function											owl:Class	
GO:0019689	biolink:NamedThing	pyrimidine nucleoside interconversion	The chemical reactions and pathways by which a pyrimidine nucleoside is synthesized from another pyrimidine nucleoside.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0098932	biolink:NamedThing	disruption by virus of host cell wall peptidoglycan during virus entry	A process carried out by a virus that breaks down peptidoglycans in the cell wall of its host during viral entry.	tmpzr1t_l9r_go_relaxed.owl	disassembly by virus of host cell wall peptidoglycan|catabolism of host cell wall peptidoglycan by virus|degradation of host cell wall peptidoglycan by virus|degradation of host peptidoglycans during virus entry				VZ:3940									biological_process											owl:Class	
GO:1905799	biolink:NamedThing	regulation of intraciliary retrograde transport	Any process that modulates the frequency, rate or extent of intraciliary retrograde transport.	tmpzr1t_l9r_go_relaxed.owl	regulation of intraflagellar retrograde transport							hbye	2017-01-11T12:58:18Z					biological_process											owl:Class	
GO:0032386	biolink:NamedThing	regulation of intracellular transport	Any process that modulates the frequency, rate or extent of the directed movement of substances within cells.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0006471	biolink:NamedThing	protein ADP-ribosylation	The transfer, from NAD, of ADP-ribose to protein amino acids.	tmpzr1t_l9r_go_relaxed.owl	protein amino acid ADP-ribosylation				RESID:AA0040|RESID:AA0295|RESID:AA0168|RESID:AA0237|RESID:AA0169|RESID:AA0231									biological_process											owl:Class	
GO:0098914	biolink:NamedThing	membrane repolarization during atrial cardiac muscle cell action potential	The process in which ions are transported across a membrane such that the atrial cardiomyocyte membrane potential changes in the direction from the positive membrane potential at the peak of the action potential towards the negative resting potential.	tmpzr1t_l9r_go_relaxed.owl	electrocardiogram QRS complex|atrial repolarization													biological_process											owl:Class	
GO:0033495	biolink:NamedThing	ferulate biosynthetic process	The chemical reactions and pathways resulting in the formation of ferulate, (2E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoate.	tmpzr1t_l9r_go_relaxed.owl	ferulate formation|ferulate biosynthesis|ferulate anabolism|ferulate synthesis				MetaCyc:PWY-5168									biological_process											owl:Class	
GO:0071135	biolink:NamedThing	alpha7-beta1 integrin-focal adhesion kinase complex	A protein complex that consists of an alpha7-beta1 integrin complex bound to focal adhesion kinase.	tmpzr1t_l9r_go_relaxed.owl	ITGA7-ITGB1-PTK2 complex							mah	2009-11-13T02:29:24Z					cellular_component											owl:Class	
GO:0102729	biolink:NamedThing	6-oxocampestanol hydroxylase activity	Catalysis of the reaction: H+ + 6-oxocampestanol + O2 + NADPH = cathasterone + H2O + NADP.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-715									molecular_function											owl:Class	
GO:1904388	biolink:NamedThing	negative regulation of ncRNA transcription associated with protein coding gene TSS/TES	Any process that stops, prevents or reduces the frequency, rate or extent of ncRNA transcription associated with protein coding gene TSS/TES.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of ncRNA transcription associated with protein coding gene TSS/TES|inhibition of ncRNA transcription associated with protein coding gene TSS/TES|down regulation of ncRNA transcription associated with protein coding gene TSS/TES|down-regulation of pasRNA transcription|negative regulation of pasRNA transcription|inhibition of pasRNA transcription|downregulation of pasRNA transcription|downregulation of ncRNA transcription associated with protein coding gene TSS/TES|down regulation of pasRNA transcription							dos	2015-06-23T18:11:39Z					biological_process											owl:Class	
GO:0045892	biolink:NamedThing	negative regulation of transcription, DNA-templated	Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.	tmpzr1t_l9r_go_relaxed.owl	downregulation of transcription, DNA-dependent|down regulation of gene-specific transcription|negative regulation of cellular transcription, DNA-dependent|down-regulation of gene-specific transcription|inhibition of transcription, DNA-dependent|downregulation of gene-specific transcription|transcription repressor activity|negative regulation of transcription, DNA-dependent|inhibition of gene-specific transcription|down regulation of transcription, DNA-dependent|negative regulation of gene-specific transcription|down-regulation of transcription, DNA-dependent											GO:0032582|GO:0016481|GO:0061021		biological_process											owl:Class	
GO:0003171	biolink:NamedThing	atrioventricular valve development	The progression of the atrioventricular valve over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl	AV valve development							dph	2009-10-08T11:14:21Z					biological_process											owl:Class	
GO:0003170	biolink:NamedThing	heart valve development	The progression of a heart valve over time, from its formation to the mature structure. A heart valve is a structure that restricts the flow of blood to different regions of the heart and forms from an endocardial cushion.	tmpzr1t_l9r_go_relaxed.owl	cardiac valve development							dph	2009-10-08T10:50:09Z					biological_process											owl:Class	
GO:0072080	biolink:NamedThing	nephron tubule development	The progression of a nephron tubule over time, from its initial formation to the mature structure. A nephron tubule is an epithelial tube that is part of the nephron, the functional part of the kidney.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-02-01T02:32:12Z					biological_process											owl:Class	
GO:1990398	biolink:NamedThing	Cus cation efflux complex	Transmembrane complex that mediates resistance to copper and silver by cation efflux directly from the cell using the proton-motive force. Spans the inner membrane, periplasm, and outer membrane. Primarily activated under anaerobic conditions by CusR and CusS but also expressed under extreme copper stress, in aerobic growth.	tmpzr1t_l9r_go_relaxed.owl	copper efflux system|copper efflux complex|Cus cation efflux system|silver efflux system|silver efflux complex					An example of this is CusA in E. coli (UniProt symbol P38054) in PMID:23122209.		bhm	2014-06-11T08:51:48Z					cellular_component											owl:Class	
GO:1904433	biolink:NamedThing	negative regulation of ferrous iron binding	Any process that stops, prevents or reduces the frequency, rate or extent of ferrous iron binding.	tmpzr1t_l9r_go_relaxed.owl	inhibition of ferrous iron binding|down-regulation of ferrous iron binding|downregulation of ferrous iron binding|down regulation of ferrous iron binding							kom	2015-07-06T13:46:36Z					biological_process											owl:Class	
GO:2001197	biolink:NamedThing	basement membrane assembly involved in embryonic body morphogenesis	Any basement membrane assembly that is involved in embryonic body morphogenesis.	tmpzr1t_l9r_go_relaxed.owl								kmv	2011-11-03T08:44:33Z					biological_process											owl:Class	
GO:0070831	biolink:NamedThing	basement membrane assembly	The aggregation, arrangement and bonding together of a set of components to form a basement membrane, a part of the extracellular region that consists of a thin layer of dense material found in various animal tissues interposed between the cells and the adjacent connective tissue.	tmpzr1t_l9r_go_relaxed.owl						Note that this term has no relationship to 'membrane assembly ; GO:0071709' because the basement membrane is not a lipid bilayer.		mah	2009-07-23T05:01:51Z					biological_process											owl:Class	
GO:1902392	biolink:NamedThing	regulation of exodeoxyribonuclease activity	Any process that modulates the frequency, rate or extent of exodeoxyribonuclease activity.	tmpzr1t_l9r_go_relaxed.owl								jl	2013-09-11T14:56:14Z					biological_process											owl:Class	
GO:1901963	biolink:NamedThing	regulation of cell proliferation involved in outflow tract morphogenesis	Any process that modulates the frequency, rate or extent of cell proliferation involved in outflow tract morphogenesis.	tmpzr1t_l9r_go_relaxed.owl								dph	2013-02-20T20:30:26Z					biological_process											owl:Class	
GO:0071696	biolink:NamedThing	ectodermal placode development	The progression of an ectodermal placode over time from its initial formation until its mature state. An ectodermal placode is a thickening of the ectoderm that is the primordium of many structures derived from the ectoderm.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-03-02T11:48:01Z					biological_process											owl:Class	
GO:0006195	biolink:NamedThing	purine nucleotide catabolic process	The chemical reactions and pathways resulting in the breakdown of a purine nucleotide, a compound consisting of nucleoside (a purine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.	tmpzr1t_l9r_go_relaxed.owl	purine nucleotide catabolism|purine nucleotide breakdown|purine nucleotide degradation													biological_process											owl:Class	
GO:1900863	biolink:NamedThing	positive regulation of cordyol C biosynthetic process	Any process that activates or increases the frequency, rate or extent of cordyol C biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	upregulation of cordyol C biosynthetic process|up regulation of cordyol C biosynthetic process|up-regulation of cordyol C biosynthetic process|activation of cordyol C biosynthetic process							di	2012-06-07T01:56:46Z					biological_process											owl:Class	
GO:0047651	biolink:NamedThing	alkylhalidase activity	Catalysis of the reaction: bromochloromethane + H(2)O = bromide + chloride + formaldehyde + 2 H(+).	tmpzr1t_l9r_go_relaxed.owl	alkyl-halide halidohydrolase activity|haloalkane halidohydrolase activity|halogenase activity				MetaCyc:ALKYLHALIDASE-RXN|KEGG_REACTION:R03523|RHEA:13765									molecular_function											owl:Class	
GO:0019120	biolink:NamedThing	hydrolase activity, acting on acid halide bonds, in C-halide compounds	Catalysis of the hydrolysis of any acid halide bond in substances containing halogen atoms in organic linkage.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-9011595|EC:3.8.1.-									molecular_function											owl:Class	
GO:0046192	biolink:NamedThing	anaerobic phenol-containing compound biosynthetic process	The chemical reactions and pathways resulting in the formation of a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring, in the absence of oxygen.	tmpzr1t_l9r_go_relaxed.owl	anaerobic phenol-containing compound anabolism|anaerobic phenol-containing compound synthesis|anaerobic phenol-containing compound formation|anaerobic phenol-containing compound biosynthesis													biological_process											owl:Class	
GO:0042215	biolink:NamedThing	anaerobic phenol-containing compound metabolic process	The chemical reactions and pathways involving a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring, in the absence of oxygen.	tmpzr1t_l9r_go_relaxed.owl	anaerobic phenol-containing compound metabolism				UM-BBD_pathwayID:phe									biological_process											owl:Class	
GO:0010909	biolink:NamedThing	positive regulation of heparan sulfate proteoglycan biosynthetic process	Any process that increases the rate, frequency or extent of heparan sulfate proteoglycan biosynthesis. Heparan sulfate proteoglycan biosynthetic processes are the chemical reactions and pathways resulting in the formation of the heparan sulfate proteoglycan, a glycosaminoglycan with repeat unit consisting of alternating alpha-(1->4)-linked hexuronic acid and glucosamine residues.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0010908	biolink:NamedThing	regulation of heparan sulfate proteoglycan biosynthetic process	Any process that modulates the rate, frequency or extent of heparan sulfate proteoglycan biosynthesis. Heparan sulfate proteoglycan biosynthetic processes are the chemical reactions and pathways resulting in the formation of the heparan sulfate proteoglycan, a glycosaminoglycan with repeat unit consisting of alternating alpha-(1->4)-linked hexuronic acid and glucosamine residues.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1904364	biolink:NamedThing	positive regulation of calcitonin secretion	Any process that activates or increases the frequency, rate or extent of calcitonin secretion.	tmpzr1t_l9r_go_relaxed.owl	up regulation of calcitonin secretion|up-regulation of calcitonin secretion|upregulation of calcitonin secretion|activation of calcitonin secretion							sl	2015-06-15T17:55:05Z					biological_process											owl:Class	
GO:0090277	biolink:NamedThing	positive regulation of peptide hormone secretion	Any process that increases the rate, frequency, or extent of the regulated release of a peptide hormone from secretory granules.	tmpzr1t_l9r_go_relaxed.owl								tb	2010-02-05T02:56:39Z					biological_process											owl:Class	
GO:0006780	biolink:NamedThing	uroporphyrinogen III biosynthetic process	The chemical reactions and pathways resulting in the formation of uroporphyrinogen III.	tmpzr1t_l9r_go_relaxed.owl	uroporphyrinogen III formation|uroporphyrinogen III biosynthesis|uroporphyrinogen III synthesis|uroporphyrinogen III anabolism													biological_process											owl:Class	
GO:0006779	biolink:NamedThing	porphyrin-containing compound biosynthetic process	The chemical reactions and pathways resulting in the formation of any member of a large group of derivatives or analogs of porphyrin. Porphyrin consists of a ring of four pyrrole nuclei linked each to the next at their alpha positions through a methine group.	tmpzr1t_l9r_go_relaxed.owl	porphyrin synthesis|porphyrin anabolism|porphyrin formation|porphyrin biosynthetic process|porphyrin biosynthesis													biological_process											owl:Class	
GO:0000915	biolink:NamedThing	actomyosin contractile ring assembly	The process of assembly of a ring composed of actin, myosin, and associated proteins that will function in cytokinesis.	tmpzr1t_l9r_go_relaxed.owl	cytokinesis, actomyosin ring formation|cytokinesis, contractile ring assembly|cytokinesis, actomyosin contractile ring assembly|cytokinesis, actomyosin ring biosynthesis|contractile ring assembly|cytokinesis, actomyosin contractile ring formation|constriction ring assembly											GO:0045573		biological_process											owl:Class	
GO:0000912	biolink:NamedThing	assembly of actomyosin apparatus involved in cytokinesis	The assembly and arrangement of an apparatus composed of actin, myosin, and associated proteins that will function in cytokinesis.	tmpzr1t_l9r_go_relaxed.owl	actomyosin apparatus assembly involved in cytokinesis|cytokinesis, formation of actomyosin apparatus|formation of actomyosin apparatus involved in cytokinesis													biological_process											owl:Class	
GO:0007308	biolink:NamedThing	oocyte construction	The synthesis, deposition, and organization of the materials in a cell of an ovary; where the cell can then undergo meiosis and form an ovum. An example of this is found in Drosophila melanogaster.	tmpzr1t_l9r_go_relaxed.owl	oocyte arrangement											GO:0048110		biological_process											owl:Class	
GO:0097502	biolink:NamedThing	mannosylation	The covalent attachment of a mannose residue to a substrate molecule.	tmpzr1t_l9r_go_relaxed.owl								pr	2013-09-20T09:47:40Z					biological_process											owl:Class	
GO:0070085	biolink:NamedThing	glycosylation	The covalent attachment and further modification of carbohydrate residues to a substrate molecule.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Glycosylation									biological_process											owl:Class	
GO:0071079	biolink:NamedThing	alpha2-beta1 integrin-chondroadherin complex	A protein complex that consists of an alpha2-beta1 integrin complex bound to the cartilage matrix protein chondroadherin.	tmpzr1t_l9r_go_relaxed.owl	ITGA2-ITGB1-CHAD complex							mah	2009-11-06T04:42:55Z					cellular_component											owl:Class	
GO:0032306	biolink:NamedThing	regulation of prostaglandin secretion	Any process that modulates the frequency, rate or extent of the regulated release of a prostaglandin from a cell.	tmpzr1t_l9r_go_relaxed.owl	regulation of prostacyclin secretion													biological_process											owl:Class	
GO:0061723	biolink:NamedThing	glycophagy	The selective autophagy process in which cellular glycogen is delivered to the vacuole and degraded in response to changing cellular conditions.	tmpzr1t_l9r_go_relaxed.owl								dph	2015-07-08T13:36:51Z					biological_process											owl:Class	
GO:0061448	biolink:NamedThing	connective tissue development	The progression of a connective tissue over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl								dph	2012-03-22T12:53:41Z					biological_process											owl:Class	
GO:1903035	biolink:NamedThing	negative regulation of response to wounding	Any process that stops, prevents or reduces the frequency, rate or extent of response to wounding.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of response to wounding|down regulation of response to wounding|inhibition of response to wounding|negative regulation of physiological response to wounding|downregulation of physiological response to wounding|inhibition of physiological response to wounding|downregulation of response to wounding|down-regulation of physiological response to wounding|down regulation of physiological response to wounding							kmv	2014-05-18T01:28:52Z					biological_process											owl:Class	
GO:0008390	biolink:NamedThing	testosterone 16-alpha-hydroxylase activity	Catalysis of the reaction: testosterone + donor-H2 + O2 = 16-alpha-hydroxytestosterone + H2O.	tmpzr1t_l9r_go_relaxed.owl	cytochrome P450 CYP2B9|cytochrome P450 CYP2D9|cytochrome P450 CYP2D11|cytochrome P450 CYP2D10|cytochrome P450 CYP2B10													molecular_function											owl:Class	
GO:0004559	biolink:NamedThing	alpha-mannosidase activity	Catalysis of the hydrolysis of terminal, non-reducing alpha-D-mannose residues in alpha-D-mannosides.	tmpzr1t_l9r_go_relaxed.owl	1,2-alpha-D-mannosidase activity|1,2-alpha-mannosidase|alpha-D-mannoside mannohydrolase activity|exo-alpha-mannosidase activity|alpha-D-mannopyranosidase activity|alpha-D-mannosidase activity|p-nitrophenyl-alpha-mannosidase activity				MetaCyc:3.2.1.24-RXN|Reactome:R-HSA-9694656|Reactome:R-HSA-8853686|EC:3.2.1.24|Reactome:R-HSA-6799545									molecular_function											owl:Class	
GO:0015923	biolink:NamedThing	mannosidase activity	Catalysis of the hydrolysis of mannosyl compounds, substances containing a group derived from a cyclic form of mannose or a mannose derivative.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1901009	biolink:NamedThing	(S)-scoulerine biosynthetic process	The chemical reactions and pathways resulting in the formation of (S)-scoulerine.	tmpzr1t_l9r_go_relaxed.owl	(S)-scoulerine synthesis|(S)-scoulerine biosynthesis|(S)-scoulerine anabolism|(S)-scoulerine formation							yaf	2012-06-15T10:46:17Z					biological_process											owl:Class	
GO:0033075	biolink:NamedThing	isoquinoline alkaloid biosynthetic process	The chemical reactions and pathways resulting in the formation of isoquinoline alkaloids, alkaloid compounds that contain bicyclic N-containing aromatic rings and are derived from a 3,4-dihydroxytyramine (dopamine) precursor that undergoes a Schiff base addition with aldehydes of different origin.	tmpzr1t_l9r_go_relaxed.owl	isoquinoline alkaloid formation|ipecac alkaloid biosynthesis|isoquinoline alkaloid synthesis|isoquinoline alkaloid anabolism|isoquinoline alkaloid biosynthesis													biological_process											owl:Class	
GO:0043670	biolink:NamedThing	foot layer	The inner layer of the ectexine.	tmpzr1t_l9r_go_relaxed.owl	nexine 1													cellular_component											owl:Class	
GO:0005342	biolink:NamedThing	organic acid transmembrane transporter activity	Enables the transfer of organic acids from one side of a membrane to the other. Organic acids are acidic compound containing carbon in covalent linkage.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0002764	biolink:NamedThing	immune response-regulating signaling pathway	The cascade of processes by which a signal interacts with a receptor, causing a change in the level or activity of a second messenger or other downstream target, and ultimately leading to the activation, perpetuation, or inhibition of an immune response.	tmpzr1t_l9r_go_relaxed.owl	immune response-regulating signalling pathway													biological_process											owl:Class	
GO:0050776	biolink:NamedThing	regulation of immune response	Any process that modulates the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0042664	biolink:NamedThing	negative regulation of endodermal cell fate specification	Any process that restricts, stops or prevents a cell from specifying into an endoderm cell.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of endodermal cell fate specification|down regulation of endodermal cell fate specification|suppression of endoderm cell fate|downregulation of endodermal cell fate specification|negative regulation of endoderm cell fate specification|inhibition of endodermal cell fate specification|suppression of endodermal cell fate													biological_process											owl:Class	
GO:1903225	biolink:NamedThing	negative regulation of endodermal cell differentiation	Any process that stops, prevents or reduces the frequency, rate or extent of endodermal cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of endoderm cell differentiation|down regulation of endodermal cell differentiation|downregulation of endodermal cell differentiation|down regulation of endoderm cell differentiation|down-regulation of endodermal cell differentiation|negative regulation of endoderm cell differentiation|inhibition of endodermal cell differentiation|inhibition of endoderm cell differentiation|downregulation of endoderm cell differentiation							als	2014-07-29T13:22:41Z					biological_process											owl:Class	
GO:1905558	biolink:NamedThing	negative regulation of mitotic nuclear envelope disassembly	Any process that stops, prevents or reduces the frequency, rate or extent of mitotic nuclear envelope disassembly.	tmpzr1t_l9r_go_relaxed.owl	down regulation of mitotic nuclear envelope catabolism|downregulation of mitotic nuclear envelope disassembly|downregulation of mitotic nuclear envelope catabolism|inhibition of mitotic nuclear envelope degradation|down regulation of mitotic nuclear envelope degradation|down-regulation of mitotic nuclear envelope breakdown|down regulation of mitotic nuclear envelope disassembly|negative regulation of mitotic nuclear envelope catabolism|negative regulation of mitotic nuclear envelope breakdown|down regulation of mitotic nuclear envelope breakdown|downregulation of mitotic nuclear envelope degradation|down-regulation of mitotic nuclear envelope disassembly|inhibition of mitotic nuclear envelope disassembly|down-regulation of mitotic nuclear envelope degradation|downregulation of mitotic nuclear envelope breakdown|inhibition of mitotic nuclear envelope breakdown|negative regulation of mitotic nuclear envelope degradation|down-regulation of mitotic nuclear envelope catabolism|inhibition of mitotic nuclear envelope catabolism							hbye	2016-10-14T13:15:08Z					biological_process											owl:Class	
GO:0045341	biolink:NamedThing	MHC class I biosynthetic process	The chemical reactions and pathways resulting in the formation of major histocompatibility protein class I.	tmpzr1t_l9r_go_relaxed.owl	MHC class I formation|MHC class I biosynthesis|major histocompatibility complex class I biosynthetic process|MHC class I anabolism|MHC class I synthesis|major histocompatibility complex class I biosynthesis													biological_process											owl:Class	
GO:0060201	biolink:NamedThing	clathrin-sculpted acetylcholine transport vesicle membrane	The lipid bilayer surrounding a clathrin-sculpted acetylcholine transport vesicle.	tmpzr1t_l9r_go_relaxed.owl	clathrin sculpted acetylcholine transport vesicle membrane|clathrin sculpted acetylcholine constitutive secretory pathway transport vesicle membrane													cellular_component											owl:Class	
GO:0030665	biolink:NamedThing	clathrin-coated vesicle membrane	The lipid bilayer surrounding a clathrin-coated vesicle.	tmpzr1t_l9r_go_relaxed.owl	clathrin coated vesicle membrane													cellular_component											owl:Class	
GO:0050572	biolink:NamedThing	L-idonate 5-dehydrogenase activity	Catalysis of the reaction: L-idonate + NAD(P)+ = 5-dehydrogluconate + NAD(P)H + H+.	tmpzr1t_l9r_go_relaxed.owl	L-idonate:NAD(P)+ oxidoreductase activity				EC:1.1.1.264|MetaCyc:1.1.1.264-RXN									molecular_function											owl:Class	
GO:1901365	biolink:NamedThing	funalenone catabolic process	The chemical reactions and pathways resulting in the breakdown of funalenone.	tmpzr1t_l9r_go_relaxed.owl	funalenone degradation|funalenone catabolism|funalenone breakdown							di	2012-09-17T18:25:29Z					biological_process											owl:Class	
GO:1901364	biolink:NamedThing	funalenone metabolic process	The chemical reactions and pathways involving funalenone.	tmpzr1t_l9r_go_relaxed.owl	funalenone metabolism							di	2012-09-17T18:24:23Z					biological_process											owl:Class	
GO:0102146	biolink:NamedThing	tricetin O-methytransferase activity	Catalysis of the reaction: tricetin + S-adenosyl-L-methionine  = H+ + 3'-O-methyltricetin + S-adenosyl-L-homocysteine.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-11582|RHEA:27493									molecular_function											owl:Class	
GO:1905771	biolink:NamedThing	negative regulation of mesodermal cell differentiation	Any process that stops, prevents or reduces the frequency, rate or extent of mesodermal cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of mesoderm cell differentiation|inhibition of mesoderm cell differentiation|downregulation of mesoderm cell differentiation|down-regulation of mesodermal cell differentiation|downregulation of mesodermal cell differentiation|down regulation of mesoderm cell differentiation|inhibition of mesodermal cell differentiation|negative regulation of mesoderm cell differentiation|down regulation of mesodermal cell differentiation							rph	2016-12-21T12:44:23Z					biological_process											owl:Class	
GO:0050807	biolink:NamedThing	regulation of synapse organization	Any process that modulates the physical form of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell).	tmpzr1t_l9r_go_relaxed.owl	regulation of synapse structure|regulation of synapse organization and biogenesis|regulation of synapse organisation													biological_process											owl:Class	
GO:0051128	biolink:NamedThing	regulation of cellular component organization	Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.	tmpzr1t_l9r_go_relaxed.owl	regulation of cellular component organization and biogenesis|regulation of cellular component organisation|regulation of cell organization|regulation of cell organisation													biological_process											owl:Class	
GO:0090154	biolink:NamedThing	positive regulation of sphingolipid biosynthetic process	Any process that increases the rate, frequency or extent of sphingolipid biosynthesis. Sphingolipid biosynthesis is the chemical reactions and pathways resulting in the formation of sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid).	tmpzr1t_l9r_go_relaxed.owl								tb	2009-12-08T03:27:33Z					biological_process											owl:Class	
GO:0051173	biolink:NamedThing	positive regulation of nitrogen compound metabolic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving nitrogen or nitrogenous compounds.	tmpzr1t_l9r_go_relaxed.owl	stimulation of nitrogen metabolic process|positive regulation of nitrogen metabolic process|upregulation of nitrogen metabolic process|positive regulation of nitrogen metabolism|activation of nitrogen metabolic process|up regulation of nitrogen metabolic process|up-regulation of nitrogen metabolic process													biological_process											owl:Class	
GO:1901097	biolink:NamedThing	negative regulation of autophagosome maturation	Any process that stops, prevents or reduces the frequency, rate or extent of autophagosome maturation.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of fusion of autophagosome with lysosome|negative regulation of autophagic vacuole fusion|downregulation of fusion of autophagosome with lysosome|downregulation of autolysosome formation|downregulation of autophagic vacuole maturation|inhibition of fusion of autophagosome with lysosome|down-regulation of autophagic vacuole maturation|negative regulation of autolysosome formation|down-regulation of fusion of autophagosome with lysosome|inhibition of autolysosome formation|down regulation of autophagic vacuole fusion|negative regulation of autophagosome fusion|down-regulation of amphisome-lysosome fusion|down-regulation of autophagosome maturation|down regulation of autolysosome formation|down regulation of amphisome-lysosome fusion|inhibition of amphisome-lysosome fusion|negative regulation of amphisome-lysosome fusion|downregulation of autophagosome maturation|inhibition of autophagic vacuole fusion|down-regulation of autolysosome formation|downregulation of amphisome-lysosome fusion|down regulation of fusion of autophagosome with lysosome|inhibition of autophagic vacuole maturation|downregulation of autophagic vacuole fusion|inhibition of autophagosome maturation|down regulation of autophagosome maturation|down-regulation of autophagic vacuole fusion|down regulation of autophagic vacuole maturation							lb	2012-07-10T07:22:26Z			GO:1902453		biological_process											owl:Class	
GO:0016242	biolink:NamedThing	negative regulation of macroautophagy	Any process that stops, prevents, or reduces the frequency, rate or extent of macroautophagy.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of macroautophagy|inhibition of macroautophagy|negative regulation of starvation-induced autophagy|downregulation of macroautophagy|down regulation of macroautophagy													biological_process											owl:Class	
GO:0005868	biolink:NamedThing	cytoplasmic dynein complex	Any dynein complex with a homodimeric dynein heavy chain core that catalyzes movement along a microtubule. Cytoplasmic dynein complexes participate in many cytoplasmic transport activities in eukaryotes, such as mRNA localization, intermediate filament transport, nuclear envelope breakdown, apoptosis, transport of centrosomal proteins, mitotic spindle assembly, virus transport, kinetochore functions, and movement of signaling and spindle checkpoint proteins. Some complexes participate in intraflagellar transport. Subunits associated with the dynein heavy chain mediate association between dynein heavy chain and cargoes, and may include light chains and light intermediate chains.	tmpzr1t_l9r_go_relaxed.owl	cytoplasmic dynein intermediate chain|cytoplasmic dynein intermediate light chain|cytoplasmic dynein heavy chain|cytoplasmic dynein light chain					Note that this term is labelled based on phylogenetic classification and community usage, rather than strict cellular localization. Cytoplasmic dynein complexes may contain ciliary dyneins; therefore the term is not linked to 'cytoplasm'. Cytoplasmic dynein complexes do not contain axonemal dyneins; see GO:0005858 axonemal dynein complex.								cellular_component											owl:Class	
GO:0007285	biolink:NamedThing	primary spermatocyte growth	The phase of growth and gene expression that male germ cells undergo as they enter the spermatocyte stage. The cells grow in volume and transcribe most of the gene products needed for the morphological events that follow meiosis.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1900998	biolink:NamedThing	nitrobenzene catabolic process	The chemical reactions and pathways resulting in the breakdown of nitrobenzene.	tmpzr1t_l9r_go_relaxed.owl	nitrobenzene catabolism|nitrobenzene breakdown|nitrobenzene degradation							yaf	2012-06-14T02:54:09Z					biological_process											owl:Class	
GO:1990762	biolink:NamedThing	cytoplasmic alanyl-tRNA aminoacylation	The process of coupling alanine to alanyl-tRNA, catalyzed by alanyl-tRNA synthetase involved in cytoplasmic translation.	tmpzr1t_l9r_go_relaxed.owl								vw	2015-06-08T15:56:51Z					biological_process											owl:Class	
GO:0006419	biolink:NamedThing	alanyl-tRNA aminoacylation	The process of coupling alanine to alanyl-tRNA, catalyzed by alanyl-tRNA synthetase. The alanyl-tRNA synthetase is a  class-II synthetases. The activated amino acid is transferred to the 3'-OH group of an alanine accetping tRNA.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0102569	biolink:NamedThing	FR-33289 synthase activity	Catalysis of the reaction: FR-900098 + 2-oxoglutarate(2-) + O2 <=> FR-33289 + succinate(2-) + carbon dioxide.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-15082									molecular_function											owl:Class	
GO:1901844	biolink:NamedThing	regulation of cell communication by electrical coupling involved in cardiac conduction	Any process that modulates the frequency, rate or extent of cell communication by electrical coupling involved in cardiac conduction.	tmpzr1t_l9r_go_relaxed.owl								rl	2013-01-24T19:15:39Z					biological_process											owl:Class	
GO:0010649	biolink:NamedThing	regulation of cell communication by electrical coupling	Any process that modulates the frequency, rate or extent of cell communication via electrical coupling. Cell communication via electrical coupling is the process that mediates signaling interactions between one cell and another cell by transfer of current between their adjacent cytoplasms via intercellular protein channels.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0033929	biolink:NamedThing	blood-group-substance endo-1,4-beta-galactosidase activity	Catalysis of the endohydrolysis of (1->4)-beta-D-galactosidic linkages in blood group A and B substances.	tmpzr1t_l9r_go_relaxed.owl	blood-group-substance 1,4-beta-D-galactanohydrolase activity|endo-beta-galactosidase activity				MetaCyc:3.2.1.102-RXN|EC:3.2.1.102									molecular_function											owl:Class	
GO:0015925	biolink:NamedThing	galactosidase activity	Catalysis of the hydrolysis of galactosyl compounds, substances containing a group derived from a cyclic form of galactose or a galactose derivative.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0052827	biolink:NamedThing	inositol pentakisphosphate phosphatase activity	Catalysis of the reaction: myo-inositol pentakisphosphate + H2O = myo-inositol tetrakisphosphate + phosphate.	tmpzr1t_l9r_go_relaxed.owl								ai	2011-11-29T09:55:04Z					molecular_function											owl:Class	
GO:0052745	biolink:NamedThing	inositol phosphate phosphatase activity	Catalysis of the reaction: inositol phosphate(n) + H2O = inositol phosphate(n-1) + phosphate. This reaction is the removal of a phosphate group from an inositol phosphate.	tmpzr1t_l9r_go_relaxed.owl								ai	2011-09-14T01:50:04Z					molecular_function											owl:Class	
GO:0052651	biolink:NamedThing	monoacylglycerol catabolic process	The chemical reactions and pathways resulting in the breakdown of monoacylglycerol, any ester of glycerol in which any one of its hydroxyl groups has been acylated with a fatty acid, the other being non-esterified.	tmpzr1t_l9r_go_relaxed.owl	monoacylglycerol breakdown|monoacylglycerol catabolism|monoacylglycerol degradation								2010-09-23T09:26:36Z					biological_process											owl:Class	
GO:0046462	biolink:NamedThing	monoacylglycerol metabolic process	The chemical reactions and pathways involving monoacylglycerol, any ester of glycerol in which any one of its hydroxyl groups has been acylated with a fatty acid, the other being non-esterified.	tmpzr1t_l9r_go_relaxed.owl	monoacylglycerol metabolism|monoglyceride metabolic process|monoglyceride metabolism													biological_process											owl:Class	
GO:0043066	biolink:NamedThing	negative regulation of apoptotic process	Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of apoptosis|inhibition of apoptosis|pro-survival|apoptosis inhibitor activity|down regulation of apoptosis|negative regulation of apoptosis|anti-apoptosis|downregulation of apoptosis					This term should only be used when it is not possible to determine which phase or subtype of the apoptotic process is negatively regulated by a gene product. Whenever detailed information is available, the more granular children terms should be used.						GO:0006916		biological_process											owl:Class	
GO:1905479	biolink:NamedThing	negative regulation of glutamate-ammonia ligase activity	Any process that stops, prevents or reduces the frequency, rate or extent of glutamate-ammonia ligase activity.	tmpzr1t_l9r_go_relaxed.owl	downregulation of glutamine synthetase activity|downregulation of glutamylhydroxamic synthetase activity|down-regulation of L-glutamine synthetase activity|inhibition of glutamylhydroxamic synthetase activity|downregulation of L-glutamate:ammonia ligase (ADP-forming)|inhibition of glutamine synthetase activity|down regulation of L-glutamine synthetase activity|inhibition of L-glutamate:ammonia ligase (ADP-forming)|down-regulation of glutamylhydroxamic synthetase activity|down regulation of L-glutamate:ammonia ligase (ADP-forming)|down regulation of glutamine synthetase activity|inhibition of glutamate-ammonia ligase activity|downregulation of glutamate-ammonia ligase activity|inhibition of L-glutamine synthetase activity|negative regulation of glutamylhydroxamic synthetase activity|down-regulation of L-glutamate:ammonia ligase (ADP-forming)|downregulation of L-glutamine synthetase activity|negative regulation of L-glutamate:ammonia ligase (ADP-forming)|down-regulation of glutamate-ammonia ligase activity|down regulation of glutamate-ammonia ligase activity|down regulation of glutamylhydroxamic synthetase activity|negative regulation of glutamine synthetase activity|down-regulation of glutamine synthetase activity|negative regulation of L-glutamine synthetase activity							pga	2016-09-22T09:58:42Z					biological_process											owl:Class	
GO:0060726	biolink:NamedThing	regulation of coreceptor activity involved in epidermal growth factor receptor signaling pathway	Any process that modulates the rate or frequency of coreceptor activity involved in epidermal growth factor receptor signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	regulation of Neu/ErbB-2 receptor activity|regulation of coreceptor activity involved in epidermal growth factor receptor signalling pathway							dph	2009-06-12T01:25:20Z					biological_process											owl:Class	
GO:0001877	biolink:NamedThing	lipoarabinomannan immune receptor activity	Combining with lipoarabinomannan and transmitting the signal to initiate an innate immune response.	tmpzr1t_l9r_go_relaxed.owl	LAM receptor activity|lipoarabinomannan receptor activity													molecular_function											owl:Class	
GO:0038187	biolink:NamedThing	pattern recognition receptor activity	Combining with a pathogen-associated molecular pattern (PAMP), a structure conserved among microbial species to initiate an innate immune response.	tmpzr1t_l9r_go_relaxed.owl	PAMP receptor activity|signaling pattern recognition receptor activity|macrophage receptor activity|microbe-associated molecular pattern receptor activity|PRR activity|pathogen associated molecular pattern receptor activity|MAMP receptor activity|PRR	https://github.com/geneontology/go-ontology/issues/17995|https://github.com/geneontology/go-ontology/issues/18588			Wikipedia:Pattern_recognition_receptor			bf	2013-05-29T15:24:44Z			GO:0008329		molecular_function											owl:Class	
GO:0042003	biolink:NamedThing	masculinization of hermaphrodite soma	Promotion of male sex and sexual phenotypes in the hermaphroditic nematode soma. An example of this is found in Caenorhabditis elegans.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0042001	biolink:NamedThing	hermaphrodite somatic sex determination	The determination of sex and sexual phenotypes in a hermaphroditic organism's soma. An example of this is found in Caenorhabditis elegans.	tmpzr1t_l9r_go_relaxed.owl												GO:0042002		biological_process											owl:Class	
GO:0010948	biolink:NamedThing	negative regulation of cell cycle process	Any process that decreases the rate, frequency or extent of a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-04-27T09:53:22Z					biological_process											owl:Class	
GO:1904935	biolink:NamedThing	positive regulation of cell proliferation in midbrain	Any process that activates or increases the frequency, rate or extent of cell proliferation in midbrain.	tmpzr1t_l9r_go_relaxed.owl	up regulation of mesencepahalic cell proliferation|positive regulation of cell proliferation in mesencephalon|up regulation of cell proliferation in midbrain|up-regulation of cell proliferation in mesencephalon|up-regulation of cell proliferation in midbrain|up regulation of cell proliferation in mesencephalon|upregulation of mesencepahalic cell proliferation|activation of mesencepahalic cell proliferation|activation of cell proliferation in mesencephalon|positive regulation of mesencepahalic cell proliferation|activation of cell proliferation in midbrain|up-regulation of mesencepahalic cell proliferation|upregulation of cell proliferation in mesencephalon|upregulation of cell proliferation in midbrain							bf	2016-02-01T13:16:27Z					biological_process											owl:Class	
GO:2000179	biolink:NamedThing	positive regulation of neural precursor cell proliferation	Any process that activates or increases the frequency, rate or extent of neural precursor cell proliferation.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-10-13T12:40:45Z					biological_process											owl:Class	
GO:0018340	biolink:NamedThing	peptidyl-O-(sn-1-glycerophosphoryl)-L-serine biosynthetic process from peptidyl-serine	The modification of peptidyl-serine to peptidyl-O-(sn-1-glycerophosphoryl)-L-serine.	tmpzr1t_l9r_go_relaxed.owl	peptidyl-O-(sn-1-glycerophosphoryl)-L-serine formation from peptidyl-serine|peptidyl-O-(sn-1-glycerophosphoryl)-L-serine synthesis from peptidyl-serine|peptidyl-O-(sn-1-glycerophosphoryl)-L-serine anabolism from peptidyl-serine				RESID:AA0264									biological_process											owl:Class	
GO:0098976	biolink:NamedThing	excitatory chemical synaptic transmission	Synaptic transmission that results in an excitatory postsynaptic potential.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0007268	biolink:NamedThing	chemical synaptic transmission	The vesicular release of classical neurotransmitter molecules from a presynapse, across a chemical synapse, the subsequent activation of neurotransmitter receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse.	tmpzr1t_l9r_go_relaxed.owl	signal transmission across a synapse|synaptic transmission|neurotransmission				Wikipedia:Neurotransmission									biological_process											owl:Class	
GO:0052704	biolink:NamedThing	ergothioneine biosynthesis from histidine via gamma-glutamyl-hercynylcysteine sulfoxide	The pathway resulting in the formation of ergothioneine from histidine via a set of steps in which gamma-glutamyl-hercynylcysteine sulfoxide is formed as an intermediate.	tmpzr1t_l9r_go_relaxed.owl	ergothioneine biosynthesis from histidine via N-alpha,N-alpha,N-alpha-trimethyl-L-histidine	https://github.com/geneontology/go-ontology/issues/11163			Wikipedia:Ergothioneine				2011-08-05T11:31:52Z					biological_process											owl:Class	
GO:0052699	biolink:NamedThing	ergothioneine biosynthetic process	The chemical reactions and pathways resulting in the formation of ergothioneine, a naturally occurring metabolite of histidine with antioxidant properties.	tmpzr1t_l9r_go_relaxed.owl	ergothioneine biosynthesis|2-mercaptoergothioneine trimethylbetaine synthesis|2-mercaptoergothioneine trimethylbetaine biosynthetic process|2-mercaptoergothioneine trimethylbetaine biosynthesis|2-mercaptoergothioneine trimethylbetaine anabolism|2-mercaptoergothioneine trimethylbetaine formation|(2S)-3-(2-mercapto-1H-imidazol-5-yl)-2-(trimethylazaniumyl)propanoate biosynthetic process|ergothioneine anabolism|ergothioneine synthesis|ergothioneine formation							ai	2011-08-01T03:56:19Z					biological_process											owl:Class	
GO:0061149	biolink:NamedThing	BMP signaling pathway involved in ureter morphogenesis	A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, which contributes to the shaping of the ureter. The ureter is a tube that extends from the kidney to the bladder.	tmpzr1t_l9r_go_relaxed.owl	BMP signalling pathway involved in ureter morphogenesis							dph	2010-06-02T09:11:46Z					biological_process											owl:Class	
GO:0106064	biolink:NamedThing	regulation of cobalamin metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving cobalamin (vitamin B12), a water-soluble vitamin characterized by possession of a corrin nucleus containing a cobalt atom.	tmpzr1t_l9r_go_relaxed.owl								hjd	2017-10-27T17:33:05Z					biological_process											owl:Class	
GO:1901401	biolink:NamedThing	regulation of tetrapyrrole metabolic process	Any process that modulates the frequency, rate or extent of tetrapyrrole metabolic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of tetrapyrrole metabolism							tt	2012-10-01T14:34:03Z					biological_process											owl:Class	
GO:0006094	biolink:NamedThing	gluconeogenesis	The formation of glucose from noncarbohydrate precursors, such as pyruvate, amino acids and glycerol.	tmpzr1t_l9r_go_relaxed.owl	glucose biosynthesis|glucose biosynthetic process				MetaCyc:GLUCONEO-PWY|Wikipedia:Gluconeogenesis									biological_process											owl:Class	
GO:0006006	biolink:NamedThing	glucose metabolic process	The chemical reactions and pathways involving glucose, the aldohexose gluco-hexose. D-glucose is dextrorotatory and is sometimes known as dextrose; it is an important source of energy for living organisms and is found free as well as combined in homo- and hetero-oligosaccharides and polysaccharides.	tmpzr1t_l9r_go_relaxed.owl	glucose metabolism|cellular glucose metabolic process													biological_process											owl:Class	
GO:0018915	biolink:NamedThing	ethylbenzene metabolic process	The chemical reactions and pathways involving ethylbenzene (phenylethane), a benzene derivative with an ethyl group attached to the ring. It is a colorless liquid with a pungent odor used as a solvent and as a component of automotive and aviation fuels.	tmpzr1t_l9r_go_relaxed.owl	ethylbenzene metabolism				UM-BBD_pathwayID:ethb2									biological_process											owl:Class	
GO:0120252	biolink:NamedThing	hydrocarbon metabolic process	The chemical reactions and pathways involving a hydrocarbon, a compound consisting of carbon and hydrogen only.	tmpzr1t_l9r_go_relaxed.owl	hydrocarbon metabolism	https://github.com/geneontology/go-ontology/issues/19842						krc	2020-09-02T20:47:28Z					biological_process											owl:Class	
GO:0031493	biolink:NamedThing	nucleosomal histone binding	Binding to a histone that is assembled into a nucleosome.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0042393	biolink:NamedThing	histone binding	Binding to a histone, any of a group of water-soluble proteins found in association with the DNA of eukaroytic chromosomes. They are involved in the condensation and coiling of chromosomes during cell division and have also been implicated in nonspecific suppression of gene activity.	tmpzr1t_l9r_go_relaxed.owl	histone-specific chaperone activity													molecular_function											owl:Class	
GO:0009112	biolink:NamedThing	nucleobase metabolic process	The chemical reactions and pathways involving a nucleobase, a nitrogenous base that is a constituent of a nucleic acid, e.g. the purines: adenine, guanine, hypoxanthine, xanthine and the pyrimidines: cytosine, uracil, thymine.	tmpzr1t_l9r_go_relaxed.owl	nucleobase metabolism													biological_process											owl:Class	
GO:1905769	biolink:NamedThing	positive regulation of double-stranded telomeric DNA binding	Any process that activates or increases the frequency, rate or extent of double-stranded telomeric DNA binding.	tmpzr1t_l9r_go_relaxed.owl	activation of double-stranded telomeric DNA binding|upregulation of double-stranded telomeric DNA binding|up-regulation of double-stranded telomeric DNA binding|up regulation of double-stranded telomeric DNA binding							nc	2016-12-20T15:34:15Z					biological_process											owl:Class	
GO:1905767	biolink:NamedThing	regulation of double-stranded telomeric DNA binding	Any process that modulates the frequency, rate or extent of double-stranded telomeric DNA binding.	tmpzr1t_l9r_go_relaxed.owl								nc	2016-12-20T15:33:58Z					biological_process											owl:Class	
GO:1903269	biolink:NamedThing	ornithine carbamoyltransferase inhibitor complex	A protein complex which is capable of ornithine carbamoyltransferase inhibitor activity.	tmpzr1t_l9r_go_relaxed.owl	OTC-ARGI complex|ornithine carbamoyltransferase arginase complex					An example of this is ARGI in Saccharomyces cerevisiae (P00812) in PMID:12679340 (inferred from direct assay).		bhm	2014-08-08T08:47:38Z					cellular_component											owl:Class	
GO:0033746	biolink:NamedThing	histone H3-methyl-arginine-2 demethylase activity	Catalysis of the removal of the methyl group from a modified arginine residue at position 2 of the histone H3 protein. This is a dioxygenase reaction that is dependent on Fe(II) and 2-oxoglutarate.	tmpzr1t_l9r_go_relaxed.owl	histone demethylase activity (H3-R2 specific)|histone H3R2me demethylase activity	https://github.com/geneontology/go-ontology/issues/21089												molecular_function											owl:Class	
GO:0032452	biolink:NamedThing	histone demethylase activity	Catalysis of the removal of a methyl group from a histone.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-3214912|Reactome:R-HSA-5625797|Reactome:R-HSA-4724284|Reactome:R-HSA-5661120|Reactome:R-HSA-5661125|Reactome:R-HSA-5661115|Reactome:R-HSA-4754181|Reactome:R-HSA-5625848|Reactome:R-HSA-5661124|Reactome:R-HSA-5423117|Reactome:R-HSA-5661116|Reactome:R-HSA-5661123|Reactome:R-HSA-4724279|Reactome:R-HSA-5625870|Reactome:R-HSA-5661122|Reactome:R-HSA-4754176|Reactome:R-HSA-4754187|Reactome:R-HSA-4722133|Reactome:R-HSA-5661121|Reactome:R-HSA-5661114									molecular_function											owl:Class	
GO:1904876	biolink:NamedThing	negative regulation of DNA ligase activity	Any process that stops, prevents or reduces the frequency, rate or extent of DNA ligase activity.	tmpzr1t_l9r_go_relaxed.owl	inhibition of DNA ligase activity|down-regulation of DNA ligase activity|downregulation of DNA ligase activity|down regulation of DNA ligase activity							rl	2015-12-18T18:35:37Z					biological_process											owl:Class	
GO:0033986	biolink:NamedThing	response to methanol	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methanol stimulus.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0097305	biolink:NamedThing	response to alcohol	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alcohol stimulus.	tmpzr1t_l9r_go_relaxed.owl	process resulting in tolerance to alcohol							pr	2012-05-15T03:48:45Z			GO:1990335		biological_process											owl:Class	
GO:0061064	biolink:NamedThing	negative regulation of nematode larval development	Any process that decreases the rate, frequency, or extent of nematode larval development, the process whose specific outcome is the progression of the nematode larva over time, from its formation to the mature structure. Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-03-11T01:04:39Z					biological_process											owl:Class	
GO:0061062	biolink:NamedThing	regulation of nematode larval development	Any process that modulates the rate, frequency, or extent of nematode larval development, the process whose specific outcome is the progression of the nematode larva over time, from its formation to the mature structure. Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-03-11T12:59:21Z					biological_process											owl:Class	
GO:1903604	biolink:NamedThing	cytochrome metabolic process	The chemical reactions and pathways involving a cytochrome.	tmpzr1t_l9r_go_relaxed.owl	cytochrome metabolism							dph	2014-11-13T20:01:09Z					biological_process											owl:Class	
GO:0021939	biolink:NamedThing	extracellular matrix-granule cell signaling involved in regulation of granule cell precursor proliferation	The process that mediates the transfer of information from the extracellular matrix to granule cell precursors resulting in a decrease in rate of granule cell precursor cell proliferation.	tmpzr1t_l9r_go_relaxed.owl	extracellular matrix-granule cell signalling involved in regulation of granule cell precursor proliferation													biological_process											owl:Class	
GO:0009221	biolink:NamedThing	pyrimidine deoxyribonucleotide biosynthetic process	The chemical reactions and pathways resulting in the formation of a pyrimidine deoxyribonucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.	tmpzr1t_l9r_go_relaxed.owl	pyrimidine deoxyribonucleotide synthesis|pyrimidine deoxyribonucleotide anabolism|pyrimidine deoxyribonucleotide formation|pyrimidine deoxyribonucleotide biosynthesis				MetaCyc:PWY0-166									biological_process											owl:Class	
GO:0009265	biolink:NamedThing	2'-deoxyribonucleotide biosynthetic process	The chemical reactions and pathways resulting in the formation of a 2'-deoxyribonucleotide, a compound consisting of 2'-deoxyribonucleoside (a base linked to a 2'-deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.	tmpzr1t_l9r_go_relaxed.owl	2'-deoxyribonucleotide formation|2'-deoxyribonucleotide biosynthesis|2'-deoxyribonucleotide anabolism|2'-deoxyribonucleotide synthesis													biological_process											owl:Class	
GO:0097287	biolink:NamedThing	7-cyano-7-deazaguanine metabolic process	The chemical reactions and pathways involving the Q nucleoside precursor 7-cyano-7-deazaguanine, also known as 2-amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile or preQo.	tmpzr1t_l9r_go_relaxed.owl	7-cyano-7-deazaguanine metabolism							pr	2012-04-25T10:50:50Z					biological_process											owl:Class	
GO:0010162	biolink:NamedThing	seed dormancy process	A dormancy process in which dormancy (sometimes called a dormant state) is induced, maintained or broken in a seed. Seed dormancy is a suspension of most physiological activity and growth in a seed, including the embryo contained therein, that can be reactivated. It often requires special conditions for reactivation, such as specific temperature, scarification, or leaching of inhibitors.	tmpzr1t_l9r_go_relaxed.owl	seed dormancy				Wikipedia:Seed#Seed_dormancy_and_protection									biological_process											owl:Class	
GO:0022611	biolink:NamedThing	dormancy process	A developmental process in which dormancy (sometimes called a dormant state) is induced, maintained or broken. Dormancy is a suspension of most physiological activity and growth that can be reactivated.	tmpzr1t_l9r_go_relaxed.owl	multicellular organism dormancy process|spore dormancy process					In plants and animals, dormancy may be a response to environmental conditions such as seasonality or extreme heat, drought, or cold. In plants, dormancy may involve the formation of dormant buds, and may be preceded by the senescence of plant parts such as leaves in woody plants or most of the shoot system in herbaceous perennials. The exit from dormancy in vascular plants is marked by resumed growth of buds and/or growth of vascular cambium.								biological_process											owl:Class	
GO:0023056	biolink:NamedThing	positive regulation of signaling	Any process that activates, maintains or increases the frequency, rate or extent of a signaling process.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of signalling process|positive regulation of signaling process								2010-02-16T09:30:50Z					biological_process											owl:Class	
GO:0036077	biolink:NamedThing	intratendonous ossification	Ossification wherein bone tissue forms within tendonous tissue.	tmpzr1t_l9r_go_relaxed.owl						Tendonous ossification may occur via replacement ossification or metaplastic ossification or both in any one instance.		bf	2011-12-19T01:57:48Z					biological_process											owl:Class	
GO:0140598	biolink:NamedThing	lipoprotein carrier activity	Binding to and carrying a lipoprotein between two different cellular locations by moving along with the target lipoprotein.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/15917						pg	2021-02-10T06:16:26Z					molecular_function											owl:Class	
GO:0140597	biolink:NamedThing	protein carrier chaperone	Binding to and carrying a protein between two different cellular components by moving along with the target protein.	tmpzr1t_l9r_go_relaxed.owl	protein chaperone|protein carrier activity	https://github.com/geneontology/go-ontology/issues/15917|https://github.com/geneontology/go-ontology/issues/22127|https://github.com/geneontology/go-ontology/issues/22356						pg	2021-02-10T06:16:16Z					molecular_function											owl:Class	
GO:0007095	biolink:NamedThing	mitotic G2 DNA damage checkpoint signaling	A mitotic cell cycle checkpoint that detects and negatively regulates progression through the G2/M transition of the cell cycle in response to DNA damage.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of signal transduction involved in mitotic G2 DNA damage checkpoint|positive regulation of signal transduction involved in mitotic G2/M transition DNA damage checkpoint|mitotic cell cycle G2/M transition DNA damage checkpoint|G2 DNA damage checkpoint|down-regulation of signal transduction involved in mitotic G2 DNA damage checkpoint|signal transduction involved in G2/M transition DNA damage checkpoint|positive regulation of signal transduction involved in mitotic G2 DNA damage checkpoint|down-regulation of signal transduction involved in mitotic G2/M transition DNA damage checkpoint|mitotic G2 DNA damage checkpoint|G2/M transition DNA damage checkpoint|signal transduction involved in mitotic G2/M transition DNA damage checkpoint|down regulation of signal transduction involved in mitotic G2/M transition DNA damage checkpoint|down regulation of signal transduction involved in mitotic G2 DNA damage checkpoint|regulation of signal transduction involved in mitotic G2 DNA damage checkpoint|negative regulation of signal transduction involved in mitotic G2/M transition DNA damage checkpoint|regulation of signal transduction involved in mitotic G2/M transition DNA damage checkpoint|signal transduction involved in G2 DNA damage checkpoint|signal transduction involved in mitotic G2 DNA damage checkpoint|inhibition of signal transduction involved in mitotic G2 DNA damage checkpoint	https://github.com/geneontology/go-ontology/issues/20935										GO:0031572|GO:1902505|GO:1902506|GO:1902504|GO:0072425|GO:0072434		biological_process											owl:Class	
GO:0044773	biolink:NamedThing	mitotic DNA damage checkpoint signaling	A signal transduction process involved in mitotic DNA damage checkpoint.	tmpzr1t_l9r_go_relaxed.owl	intracellular signaling cascade involved in mitotic DNA damage checkpoint|intracellular signaling pathway involved in mitotic DNA damage checkpoint|intracellular signal transduction pathway involved in mitotic DNA damage checkpoint|signal transduction involved in mitotic DNA damage checkpoint|mitotic DNA damage checkpoint	https://github.com/geneontology/go-ontology/issues/20935						jl	2013-02-28T15:55:25Z			GO:1902402		biological_process											owl:Class	
GO:0061501	biolink:NamedThing	2',3'-cyclic GMP-AMP synthase activity	Catalysis of the reaction: ATP + GTP = 2 diphosphate + cyclic G-P(2'-5')A-P(3'-5') (cyclic 2',3' GAMP).	tmpzr1t_l9r_go_relaxed.owl	cyclic 2',3' GAMP synthase activity|2',3' cyclic GMP-AMP synthase activity|2',3' cyclic-GMP-AMP synthase activity|cyclic-GMP-AMP synthase activity	https://github.com/geneontology/go-ontology/issues/21980			Reactome:R-HSA-3244614|EC:2.7.7.86|RHEA:42064			dph	2013-01-04T07:17:57Z					molecular_function											owl:Class	
GO:0140699	biolink:NamedThing	cyclic GMP-AMP synthase activity	Catalysis of the reaction: ATP + GTP = 2 diphosphate + cyclic GMP-AMP.	tmpzr1t_l9r_go_relaxed.owl	cyclic-GMP-AMP synthase activity	https://github.com/geneontology/go-ontology/issues/21980				Note that this term should not be used for direct annotation. It should be possible to annotate to a more specific child term that descibes the position of the phosphate group on the cGAMP molecule.		pg	2021-08-27T05:05:37Z					molecular_function											owl:Class	
GO:0016095	biolink:NamedThing	polyprenol catabolic process	The chemical reactions and pathways resulting in the breakdown of polyprenols, prenols with more than 4 isoprenoid residues, which may be all-trans, or a mixture of cis and trans.	tmpzr1t_l9r_go_relaxed.owl	polyprenol breakdown|polyprenol degradation|polyprenol catabolism													biological_process											owl:Class	
GO:0008300	biolink:NamedThing	isoprenoid catabolic process	The chemical reactions and pathways resulting in the breakdown of an isoprenoid compound, isoprene (2-methylbuta-1,3-diene) or compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues.	tmpzr1t_l9r_go_relaxed.owl	isoprenoid catabolism|polyterpene catabolism|polyisoprenoid catabolic process|polyisoprenoid breakdown|polyisoprenoid catabolism|polyterpene catabolic process|isoprenoid degradation|polyisoprenoid degradation|isoprenoid breakdown											GO:0016097		biological_process											owl:Class	
GO:1900557	biolink:NamedThing	emericellamide biosynthetic process	The chemical reactions and pathways resulting in the formation of emericellamide.	tmpzr1t_l9r_go_relaxed.owl	emericellamide anabolism|emericellamide formation|emericellamide biosynthesis|emericellamide synthesis							di	2012-05-15T01:33:31Z					biological_process											owl:Class	
GO:0050763	biolink:NamedThing	depsipeptide biosynthetic process	The chemical reactions and pathways resulting in the formation of depsipeptides, a linear or cyclic compound composed of both amino acids and hydroxy acids in peptide and ester bonds respectively.	tmpzr1t_l9r_go_relaxed.owl	depsipeptide anabolism|depsipeptide biosynthesis|depsipeptide formation|depsipeptide synthesis													biological_process											owl:Class	
GO:0033590	biolink:NamedThing	response to cobalamin	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cobalamin (vitamin B12) stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to vitamin B12													biological_process											owl:Class	
GO:0032922	biolink:NamedThing	circadian regulation of gene expression	Any process that modulates the frequency, rate or extent of gene expression such that an expression pattern recurs with a regularity of approximately 24 hours.	tmpzr1t_l9r_go_relaxed.owl	diurnal variation of protein expression|circadian regulation of protein expression|diurnal variation of gene expression													biological_process											owl:Class	
GO:0007623	biolink:NamedThing	circadian rhythm	Any biological process in an organism that recurs with a regularity of approximately 24 hours.	tmpzr1t_l9r_go_relaxed.owl	response to circadian rhythm|circadian process|circadian response				Wikipedia:Circadian_rhythm							GO:0050895		biological_process											owl:Class	
GO:0047834	biolink:NamedThing	D-threo-aldose 1-dehydrogenase activity	Catalysis of the reaction: a D-threo-aldose + NAD+ = a D-threo-aldono-1,5-lactone + NADH.	tmpzr1t_l9r_go_relaxed.owl	(2S,3R)-aldose dehydrogenase activity|L-fucose dehydrogenase activity|dehydrogenase, L-fucose|D-threo-aldose:NAD+ 1-oxidoreductase activity|L-fucose (D-arabinose) dehydrogenase activity				RHEA:19645|MetaCyc:D-THREO-ALDOSE-1-DEHYDROGENASE-RXN|EC:1.1.1.122									molecular_function											owl:Class	
GO:0100010	biolink:NamedThing	positive regulation of fever generation by prostaglandin biosynthetic process	Any prostaglandin biosynthetic process process that positively_regulates fever generation.	tmpzr1t_l9r_go_relaxed.owl								cjm	2015-04-02T04:13:19Z					biological_process											owl:Class	
GO:0100008	biolink:NamedThing	regulation of fever generation by prostaglandin biosynthetic process	Any prostaglandin biosynthetic process process that regulates fever generation.	tmpzr1t_l9r_go_relaxed.owl								cjm	2015-04-02T04:13:19Z					biological_process											owl:Class	
GO:1902493	biolink:NamedThing	acetyltransferase complex	A protein complex which is capable of acetyltransferase activity.	tmpzr1t_l9r_go_relaxed.owl								bhm	2013-11-13T16:16:45Z					cellular_component											owl:Class	
GO:1990234	biolink:NamedThing	transferase complex	A protein complex capable of catalyzing the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor).	tmpzr1t_l9r_go_relaxed.owl								bhm	2013-11-12T13:20:12Z					cellular_component											owl:Class	
GO:0090151	biolink:NamedThing	establishment of protein localization to mitochondrial membrane	The directed movement of a protein to a specific location in the mitochondrial membrane.	tmpzr1t_l9r_go_relaxed.owl	establishment of protein localization in mitochondrial membrane|establishment of protein localisation in mitochondrial membrane							tb	2009-12-08T03:18:51Z					biological_process											owl:Class	
GO:0007006	biolink:NamedThing	mitochondrial membrane organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a mitochondrial membrane, either of the lipid bilayer surrounding a mitochondrion.	tmpzr1t_l9r_go_relaxed.owl	mitochondrial membrane organisation|mitochondrial membrane organization and biogenesis													biological_process											owl:Class	
GO:0010454	biolink:NamedThing	negative regulation of cell fate commitment	Any process that stops, prevents or reduces the frequency or rate of cell fate commitment. Cell fate commitment is the commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0010453	biolink:NamedThing	regulation of cell fate commitment	Any process that modulates the frequency, rate or extent of cell fate commitment. Cell fate commitment is the commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0018667	biolink:NamedThing	cyclohexanone monooxygenase activity	Catalysis of the reaction: cyclohexanone + NADPH + H+ + O2 = 6-hexanolide + NADP+ + H2O.	tmpzr1t_l9r_go_relaxed.owl	cyclohexanone:NADPH:oxygen oxidoreductase (6-hydroxylating, 1,2-lactonizing) activity|cyclohexanone 1,2-monooxygenase activity|cyclohexanone oxygenase activity|cyclohexanone:NADPH:oxygen oxidoreductase (lactone-forming)				MetaCyc:CYCLOHEXANONE-MONOOXYGENASE-RXN|RHEA:24068|UM-BBD_reactionID:r0166|EC:1.14.13.22									molecular_function											owl:Class	
GO:2000986	biolink:NamedThing	negative regulation of behavioral fear response	Any process that stops, prevents or reduces the frequency, rate or extent of behavioral fear response.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of behavioural fear response							yaf	2011-08-08T09:16:34Z					biological_process											owl:Class	
GO:0097120	biolink:NamedThing	receptor localization to synapse	Any process in which a receptor is transported to, and/or maintained at the synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell.	tmpzr1t_l9r_go_relaxed.owl	receptor localisation to synapse							pr	2011-07-31T09:20:30Z					biological_process											owl:Class	
GO:0140209	biolink:NamedThing	zinc ion import into endoplasmic reticulum	The directed import of zinc(2+) from the cytosol, across the endoplasmic reticulum membrane, into the endoplasmic reticulum.	tmpzr1t_l9r_go_relaxed.owl	zinc ion import across endoplasmic reticulum|zinc(2+) import into endoplasmic reticulum|zinc(2+) import across endoplasmic reticulum|zinc ion import into ER					This term covers zinc(2+) import *across* the endoplasmic reticulum membrane through a channel or pore. It does not cover import via vesicle fusion with endoplasmic reticulum membrane, as in this case transport does not involve crossing the membrane.		pg	2018-03-19T10:40:01Z					biological_process											owl:Class	
GO:0062111	biolink:NamedThing	zinc ion import into organelle	The directed import of zinc(2+) from the cytosol, across an organelle membrane, into the organelle.	tmpzr1t_l9r_go_relaxed.owl								dph	2019-02-05T15:27:38Z					biological_process											owl:Class	
GO:0110131	biolink:NamedThing	Aim21-Tda2 complex	A complex that localizes to actin cortical patches at sites of endocytosis and negatively regulates barbed end F-actin assembly, resulting in the generation of free actin pools. The Aim21-Tda2 complex is necessary for efficient endocytosis and balancing the distribution of actin between patches and cables.	tmpzr1t_l9r_go_relaxed.owl	Aim21/Tda2 complex							kmv	2018-10-09T21:08:36Z					cellular_component											owl:Class	
GO:0030276	biolink:NamedThing	clathrin binding	Binding to a clathrin heavy or light chain, the main components of the coat of coated vesicles and coated pits, and which also occurs in synaptic vesicles.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0003434	biolink:NamedThing	BMP signaling pathway involved in growth plate cartilage chondrocyte development	A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, which contributes to the progression of a growth plate cartilage chondrocyte over time.	tmpzr1t_l9r_go_relaxed.owl	BMP signalling pathway involved in growth plate cartilage chondrocyte development							dph	2009-12-22T12:50:17Z					biological_process											owl:Class	
GO:0034164	biolink:NamedThing	negative regulation of toll-like receptor 9 signaling pathway	Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 9 signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of toll-like receptor 9 signalling pathway|negative regulation of TLR9 signaling pathway													biological_process											owl:Class	
GO:2001307	biolink:NamedThing	xanthone-containing compound biosynthetic process	The chemical reactions and pathways resulting in the formation of a xanthone-containing compound.	tmpzr1t_l9r_go_relaxed.owl	xanthones biosynthetic process|xanthone biosynthetic process|xanthone-containing compound formation|xanthone biosynthesis|xanthones formation|xanthone-containing compound anabolism|xanthone-containing compound synthesis|xanthone-containing compound biosynthesis|xanthones biosynthesis|xanthones synthesis|xanthones anabolism							bf	2012-03-14T10:35:44Z					biological_process											owl:Class	
GO:2001305	biolink:NamedThing	xanthone-containing compound metabolic process	The chemical reactions and pathways involving a xanthone-containing compound.	tmpzr1t_l9r_go_relaxed.owl	xanthone metabolism|xanthones metabolism|xanthone-containing compound metabolism|xanthones metabolic process							bf	2012-03-14T10:35:38Z					biological_process											owl:Class	
GO:1901601	biolink:NamedThing	strigolactone biosynthetic process	The chemical reactions and pathways resulting in the formation of strigolactone.	tmpzr1t_l9r_go_relaxed.owl	strigolactone biosynthesis|strigolactone synthesis|strigolactone anabolism|strigolactone formation							tb	2012-11-08T01:20:13Z					biological_process											owl:Class	
GO:1901600	biolink:NamedThing	strigolactone metabolic process	The chemical reactions and pathways involving strigolactone.	tmpzr1t_l9r_go_relaxed.owl	strigolactone metabolism							tb	2012-11-08T01:20:09Z					biological_process											owl:Class	
GO:1901624	biolink:NamedThing	negative regulation of lymphocyte chemotaxis	Any process that stops, prevents or reduces the frequency, rate or extent of lymphocyte chemotaxis.	tmpzr1t_l9r_go_relaxed.owl	downregulation of lymphocyte chemotaxis|inhibition of lymphocyte chemotaxis|down-regulation of lymphocyte chemotaxis|down regulation of lymphocyte chemotaxis							tb	2012-11-13T23:03:28Z					biological_process											owl:Class	
GO:2000402	biolink:NamedThing	negative regulation of lymphocyte migration	Any process that stops, prevents or reduces the frequency, rate or extent of lymphocyte migration.	tmpzr1t_l9r_go_relaxed.owl								mah	2011-02-23T10:45:47Z					biological_process											owl:Class	
GO:1903978	biolink:NamedThing	regulation of microglial cell activation	Any process that modulates the frequency, rate or extent of microglial cell activation.	tmpzr1t_l9r_go_relaxed.owl								nc	2015-03-02T15:17:33Z					biological_process											owl:Class	
GO:1900597	biolink:NamedThing	demethylkotanin metabolic process	The chemical reactions and pathways involving demethylkotanin.	tmpzr1t_l9r_go_relaxed.owl	demethylkotanin metabolism							di	2012-05-15T06:54:52Z					biological_process											owl:Class	
GO:0035771	biolink:NamedThing	interleukin-4-mediated signaling pathway	A series of molecular signals initiated by the binding of interleukin-4 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.	tmpzr1t_l9r_go_relaxed.owl	IL-4-mediated signaling pathway|interleukin-4-mediated signalling pathway							bf	2011-04-01T10:56:46Z					biological_process											owl:Class	
GO:0046250	biolink:NamedThing	limonene biosynthetic process	The chemical reactions and pathways resulting in the formation of limonene (4-isopropenyl-1-methyl-cyclohexene), a monocyclic monoterpene.	tmpzr1t_l9r_go_relaxed.owl	limonene formation|limonene synthesis|limonene biosynthesis|limonene anabolism													biological_process											owl:Class	
GO:1900674	biolink:NamedThing	olefin biosynthetic process	The chemical reactions and pathways resulting in the formation of olefin.	tmpzr1t_l9r_go_relaxed.owl	olefin biosynthesis|olefin anabolism|olefin formation|olefin synthesis							tt	2012-05-22T04:25:03Z					biological_process											owl:Class	
GO:0019589	biolink:NamedThing	anaerobic glycerol catabolic process to propane-1,3-diol	The anaerobic chemical reactions and pathways resulting in the breakdown of glycerol into propane-1,3-diol and water.	tmpzr1t_l9r_go_relaxed.owl	glycerol fermentation to 1,3-propanediol|glycerol fermentation to propane-1,3-diol				MetaCyc:GOLPDLCAT-PWY									biological_process											owl:Class	
GO:0051143	biolink:NamedThing	propanediol metabolic process	The chemical reactions and pathways involving propanediol, CH3-CHOH-CH2OH, a sweet, colorless, viscous, hygroscopic liquid used as an antifreeze, in brake fluid and as a humectant in cosmetics and personal care items.	tmpzr1t_l9r_go_relaxed.owl	1,2-dihydroxypropane metabolic process|propanediol metabolism|propylene glycol metabolic process|1,2-dihydroxypropane metabolism|propylene glycol metabolism													biological_process											owl:Class	
GO:0052062	biolink:NamedThing	induction by symbiont of host phytoalexin production	The activation by a symbiont of the production of phytoalexins as part of the defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	activation by organism of host phytoalexin production|induction by organism of phytoalexin production in other organism involved in symbiotic interaction											GO:0052262		biological_process											owl:Class	
GO:0052559	biolink:NamedThing	induction by symbiont of host immune response	Any process in which a symbiont activates the immune response of the host organism; the immune response is any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	positive regulation by symbiont of host immune response|induction by organism of immune response of other organism involved in symbiotic interaction|upregulation by symbiont of host immune response|stimulation by symbiont of host immune response|activation by symbiont of host immune response|up-regulation by symbiont of host immune response|positive regulation by organism of immune response of other organism involved in symbiotic interaction|up regulation by symbiont of host immune response											GO:0052556|GO:0052555|GO:0052558		biological_process											owl:Class	
GO:0097207	biolink:NamedThing	bud dormancy process	A dormancy process in which dormancy (sometimes called a dormant state) is induced, maintained or broken in a bud. Bud dormancy is a suspension of most physiological activity and growth that can be reactivated. It may be a response to environmental conditions such as seasonality or extreme heat, drought, or cold. The exit from bud dormancy is marked by the resumed growth of the bud.	tmpzr1t_l9r_go_relaxed.owl	bud dormancy					Bud dormancy may precede dormancy of the whole plant.		pr	2012-01-04T01:18:24Z					biological_process											owl:Class	
GO:1903444	biolink:NamedThing	negative regulation of brown fat cell differentiation	Any process that stops, prevents or reduces the frequency, rate or extent of brown fat cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	inhibition of brown adipocyte cell differentiation|downregulation of brown adipocyte cell differentiation|inhibition of brown adipocyte differentiation|inhibition of brown fat cell differentiation|negative regulation of brown adipocyte cell differentiation|down-regulation of brown fat cell differentiation|downregulation of brown fat cell differentiation|down-regulation of brown adipocyte cell differentiation|down regulation of brown fat cell differentiation|down regulation of brown adipocyte cell differentiation|down-regulation of brown adipocyte differentiation|down regulation of brown adipocyte differentiation|negative regulation of brown adipocyte differentiation|downregulation of brown adipocyte differentiation							hjd	2014-09-17T19:15:00Z					biological_process											owl:Class	
GO:0090335	biolink:NamedThing	regulation of brown fat cell differentiation	Any process that modulates the rate, frequency, or extent of brown fat cell differentiation. Brown fat cell differentiation is the process in which a relatively unspecialized cell acquires specialized features of a brown adipocyte, an animal connective tissue cell involved in adaptive thermogenesis. Brown adipocytes contain multiple small droplets of triglycerides and a high number of mitochondria.	tmpzr1t_l9r_go_relaxed.owl								tb	2010-06-01T03:16:57Z					biological_process											owl:Class	
GO:0055116	biolink:NamedThing	entry into reproductive diapause	The dormancy process that results in entry into reproductive diapause. Reproductive diapause is a form of diapause where the organism itself will remain fully active, including feeding and other routine activities, but the reproductive organs experience a tissue-specific reduction in metabolism, with characteristic triggering and releasing stimuli.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0055115	biolink:NamedThing	entry into diapause	The dormancy process that results in entry into diapause. Diapause is a neurohormonally mediated, dynamic state of low metabolic activity. Associated characteristics of this form of dormancy include reduced morphogenesis, increased resistance to environmental extremes, and altered or reduced behavioral activity. Full expression develops in a species-specific manner, usually in response to a number of environmental stimuli that precede unfavorable conditions. Once diapause has begun, metabolic activity is suppressed even if conditions favorable for development prevail. Once initiated, only certain stimuli are capable of releasing the organism from this state, and this characteristic is essential in distinguishing diapause from hibernation.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Diapause									biological_process											owl:Class	
GO:0043386	biolink:NamedThing	mycotoxin biosynthetic process	The chemical reactions and pathways resulting in the formation of a mycotoxin, any poisonous substance produced by a fungus.	tmpzr1t_l9r_go_relaxed.owl	mycotoxin biosynthesis|mycotoxin anabolism|mycotoxin formation|mycotoxin synthesis													biological_process											owl:Class	
GO:0043385	biolink:NamedThing	mycotoxin metabolic process	The chemical reactions and pathways involving a mycotoxin, any poisonous substance produced by a fungus.	tmpzr1t_l9r_go_relaxed.owl	mycotoxin metabolism													biological_process											owl:Class	
GO:1900604	biolink:NamedThing	tensidol A catabolic process	The chemical reactions and pathways resulting in the breakdown of tensidol A.	tmpzr1t_l9r_go_relaxed.owl	tensidol A catabolism|tensidol A degradation|tensidol A breakdown							di	2012-05-15T06:58:09Z					biological_process											owl:Class	
GO:0008990	biolink:NamedThing	rRNA (guanine-N2-)-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing N2-methylguanine.	tmpzr1t_l9r_go_relaxed.owl	S-adenosyl-L-methionine:rRNA (guanine-2-N-)-methyltransferase activity|S-adenosyl-L-methionine:rRNA (guanine-N2-)-methyltransferase activity|ribosomal ribonucleate guanine-2-methyltransferase activity				EC:2.1.1.52|MetaCyc:RRNA-GUANINE-N2--METHYLTRANSFERASE-RXN									molecular_function											owl:Class	
GO:0008170	biolink:NamedThing	N-methyltransferase activity	Catalysis of the transfer of a methyl group to the nitrogen atom of an acceptor molecule.	tmpzr1t_l9r_go_relaxed.owl					EC:2.1.1.-									molecular_function											owl:Class	
GO:0070051	biolink:NamedThing	fibrinogen binding	Binding to fibrinogen, a highly soluble hexameric glycoprotein complex that is found in blood plasma and is converted to fibrin by thrombin in the coagulation cascade.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0044877	biolink:NamedThing	protein-containing complex binding	Binding to a macromolecular complex.	tmpzr1t_l9r_go_relaxed.owl	macromolecular complex binding|protein complex binding							jl	2014-12-16T11:38:58Z			GO:0032403		molecular_function											owl:Class	
GO:0032197	biolink:NamedThing	transposition, RNA-mediated	Any process involved in a type of transpositional recombination which occurs via an RNA intermediate.	tmpzr1t_l9r_go_relaxed.owl	retrotransposon transposition|Ty element transposition|Ty2 element transposition|Ty3 element transposition|Tf transposition|RNA-mediated transposition|retrotransposition|Ty1 element transposition|Class I transposition				Wikipedia:Transposon##Class_I:_Retrotransposons							GO:0006322|GO:0006320|GO:0006321|GO:0006319		biological_process											owl:Class	
GO:0032196	biolink:NamedThing	transposition	Any process involved in mediating the movement of discrete segments of DNA between nonhomologous sites.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Transposon									biological_process											owl:Class	
GO:0036396	biolink:NamedThing	RNA N6-methyladenosine methyltransferase complex	A RNA methyltransferase complex that catalyzes the post-transcriptional methylation of adenosine to form N6-methyladenosine (m6A). In budding yeast, the MIS complex consists of Mum2p, Ime4p and Slz1p. In vertebrates, the complex consists of METTL3, METTL14 and associated components WTAP, ZC3H13, VIRMA, CBLL1/HAKAI and in some cases of RBM15 (RBM15 or RBM15B).	tmpzr1t_l9r_go_relaxed.owl	m(6)A writer complex|m6A methyltransferase complex|MIS complex|METTL3-METTL14-WTAP methyltransferase complex|WMM complex|Mum2, Ime4, and Slz1 complex							bf	2013-07-15T10:17:50Z					cellular_component											owl:Class	
GO:0045293	biolink:NamedThing	mRNA editing complex	A protein complex that posttranscriptionally catalyzes insertion, deletion or substitution of nucleotides at multiple sites within nascent mRNA transcripts to produce mature mRNAs in eukaryotes.	tmpzr1t_l9r_go_relaxed.owl	editosome													cellular_component											owl:Class	
GO:2000957	biolink:NamedThing	regulation of cyclodextrin catabolic process	Any process that modulates the frequency, rate or extent of cyclodextrin catabolic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of cyclodextrin catabolism							tt	2011-08-01T02:23:55Z					biological_process											owl:Class	
GO:0034689	biolink:NamedThing	integrin alphaX-beta2 complex	An integrin complex that comprises one alphaX subunit and one beta2 subunit.	tmpzr1t_l9r_go_relaxed.owl	alphaX-beta2 integrin complex|Itgax-Itgb2 complex													cellular_component											owl:Class	
GO:0008305	biolink:NamedThing	integrin complex	A protein complex that is composed of one alpha subunit and one beta subunit, both of which are members of the integrin superfamily of cell adhesion receptors; the complex spans the plasma membrane and binds to extracellular matrix ligands, cell-surface ligands, and soluble ligands.	tmpzr1t_l9r_go_relaxed.owl	laminin receptor protein													cellular_component											owl:Class	
GO:0000166	biolink:NamedThing	nucleotide binding	Binding to a nucleotide, any compound consisting of a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose or deoxyribose.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0097637	biolink:NamedThing	integral component of autophagosome membrane	The component of the autophagosome membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.	tmpzr1t_l9r_go_relaxed.owl	autophagic vacuole integral membrane protein|integral component of autophagic vacuole membrane|integral to autophagic vacuole membrane													cellular_component											owl:Class	
GO:0051904	biolink:NamedThing	pigment granule transport	The directed movement of pigment granules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	pigment granule translocation													biological_process											owl:Class	
GO:0051875	biolink:NamedThing	pigment granule localization	Any process in which a pigment granule is transported to, and/or maintained in, a specific location within the cell.	tmpzr1t_l9r_go_relaxed.owl	pigment granule localisation													biological_process											owl:Class	
GO:0034012	biolink:NamedThing	FAD-AMP lyase (cyclizing) activity	Catalysis of the reaction: FAD = AMP + riboflavin cyclic-4',5'-phosphate.	tmpzr1t_l9r_go_relaxed.owl	FMN cyclase activity|FAD AMP-lyase (riboflavin-cyclic-4',5'-phosphate-forming) activity|FAD AMP-lyase (cyclic-FMN-forming) activity				EC:4.6.1.15|RHEA:13729									molecular_function											owl:Class	
GO:0009975	biolink:NamedThing	cyclase activity	Catalysis of a ring closure reaction.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0048010	biolink:NamedThing	vascular endothelial growth factor receptor signaling pathway	Any series of molecular signals initiated by the binding of an extracellular ligand to a vascular endothelial growth factor receptor (VEGFR) located on the surface of the receiving cell, and ending with regulation of a downstream cellular process, e.g. transcription.	tmpzr1t_l9r_go_relaxed.owl	VEGF receptor signaling pathway|VEGF receptor signalling pathway|VEGFR signaling pathway					In GO, a gene product with 'vascular endothelial growth factor-activated receptor activity ; GO:0005021' necessarily binds VEGF to transduce a signal. In contrast, the VEGFR refers to PR:000001971. To represent cross-talk between ligands and receptors, signaling pathways in GO are starting to be named after the receptor and/or the signal. GO:0048010 is for annotation of any pathway in which a ligand (VEGF or an alternative growth factor) binds and activates a VEGFR (PR:000001971). For annotation of signaling pathways where a VEGF binds to a cell surface receptor (VEGFR, PDGFR etc.), consider 'vascular endothelial growth factor signaling pathway ; GO:0038084'.								biological_process											owl:Class	
GO:0007169	biolink:NamedThing	transmembrane receptor protein tyrosine kinase signaling pathway	A series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell where the receptor possesses tyrosine kinase activity, and ending with regulation of a downstream cellular process, e.g. transcription.	tmpzr1t_l9r_go_relaxed.owl	transmembrane receptor protein tyrosine kinase signalling pathway													biological_process											owl:Class	
GO:0075246	biolink:NamedThing	negative regulation of oospore formation	Any process that stops, prevents, or reduces the frequency, rate or extent of oospore formation, a process in which male and female gametangia develop and fuse to form a thick-walled resting spore of oomycetes.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0043942	biolink:NamedThing	negative regulation of sexual sporulation resulting in formation of a cellular spore	Any process that stops, prevents, or reduces the frequency, rate or extent of the formation of cellular spores derived from the products of meiosis.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1903060	biolink:NamedThing	negative regulation of protein lipidation	Any process that stops, prevents or reduces the frequency, rate or extent of protein lipidation.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of protein amino acid lipidation|inhibition of protein lipidation|inhibition of protein amino acid lipidation|down regulation of protein lipidation|negative regulation of lipid:protein modification|downregulation of protein amino acid lipidation|down-regulation of lipid:protein modification|downregulation of lipid:protein modification|down regulation of protein amino acid lipidation|downregulation of protein lipidation|negative regulation of protein amino acid lipidation|inhibition of lipid:protein modification|down regulation of lipid:protein modification|down-regulation of protein lipidation							rph	2014-05-28T13:21:25Z					biological_process											owl:Class	
GO:0071077	biolink:NamedThing	adenosine 3',5'-bisphosphate transmembrane transporter activity	Enables the transfer of adenosine 3',5'-bisphosphate from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	adenosine 3',5'-diphosphate transporter activity|adenosine 3'-phosphate-5'-phosphate transmembrane transporter activity							mah	2009-11-06T03:44:14Z					molecular_function											owl:Class	
GO:0005346	biolink:NamedThing	purine ribonucleotide transmembrane transporter activity	Enables the transfer of a purine ribonucleotide, any compound consisting of a purine ribonucleoside (a purine organic base attached to a ribose sugar) esterified with (ortho)phosphate, from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0030977	biolink:NamedThing	taurine binding	Binding to taurine.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0043210	biolink:NamedThing	alkanesulfonate binding	Binding to alkanesulfonates, the anion of alkanesulfonic acids, sulfonic acid derivatives containing an aliphatic hydrocarbon group.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0000940	biolink:NamedThing	outer kinetochore	The region of a kinetochore most external to centromeric DNA; this outer region mediates kinetochore-microtubule interactions.	tmpzr1t_l9r_go_relaxed.owl	condensed chromosome outer kinetochore|outer kinetochore of condensed nuclear chromosome|condensed nuclear chromosome outer kinetochore|outer kinetochore of condensed chromosome|outer kinetochore plate	https://github.com/geneontology/go-ontology/issues/21126										GO:0000942		cellular_component											owl:Class	
GO:0043058	biolink:NamedThing	regulation of backward locomotion	Any process that modulates the speed, mechanical force, or rhythm of the posterior movement of an organism.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1904752	biolink:NamedThing	regulation of vascular associated smooth muscle cell migration	Any process that modulates the frequency, rate or extent of vascular associated smooth muscle cell migration.	tmpzr1t_l9r_go_relaxed.owl	regulation of vascular smooth muscle cell migration							rph	2015-10-19T15:49:52Z					biological_process											owl:Class	
GO:0043400	biolink:NamedThing	cortisol secretion	The regulated release of cortisol, a steroid hormone that in humans is the major circulating hormone of the cortex, or outer layer, of the adrenal gland.	tmpzr1t_l9r_go_relaxed.owl	hydrocortisone secretion													biological_process											owl:Class	
GO:0035933	biolink:NamedThing	glucocorticoid secretion	The regulated release of any glucocorticoid hormone into the circulatory system. Glucocorticoids are a class of steroid hormones that regulate a variety of physiological processes, in particular control of the concentration of glucose in blood.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-07-20T01:08:37Z					biological_process											owl:Class	
GO:2000081	biolink:NamedThing	positive regulation of canonical Wnt signaling pathway involved in controlling type B pancreatic cell proliferation	Any process that activates or increases the frequency, rate or extent of canonical Wnt signaling pathway modulating the rate or frequency of pancreatic B cell proliferation.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of canonical Wnt receptor signalling pathway involved in controlling type B pancreatic cell proliferation|positive regulation of canonical Wnt-activated signaling pathway involved in controlling type B pancreatic cell proliferation|positive regulation of canonical Wnt receptor signalling pathway involved in controlling pancreatic B cell proliferation|positive regulation of canonical Wnt receptor signaling pathway involved in pancreatic beta cell proliferation|positive regulation of canonical Wnt receptor signaling pathway involved in controlling type B pancreatic cell proliferation|positive regulation of canonical Wnt receptor signaling pathway involved in controlling pancreatic B cell proliferation							tb	2010-08-27T11:23:00Z					biological_process											owl:Class	
GO:2000079	biolink:NamedThing	regulation of canonical Wnt signaling pathway involved in controlling type B pancreatic cell proliferation	Any process that modulates the frequency, rate or extent of canonical Wnt signaling pathway modulating the rate or frequency of pancreatic B cell proliferation.	tmpzr1t_l9r_go_relaxed.owl	regulation of canonical Wnt receptor signaling pathway involved in controlling type B pancreatic cell proliferation|regulation of canonical Wnt receptor signalling pathway involved in controlling type B pancreatic cell proliferation|regulation of canonical Wnt receptor signaling pathway involved in pancreatic beta cell proliferation|regulation of canonical Wnt receptor signalling pathway involved in controlling pancreatic B cell proliferation|regulation of canonical Wnt-activated signaling pathway involved in controlling type B pancreatic cell proliferation|regulation of canonical Wnt receptor signaling pathway involved in controlling pancreatic B cell proliferation							tb	2010-08-27T11:22:56Z					biological_process											owl:Class	
GO:0047957	biolink:NamedThing	4'-methoxyisoflavone 2'-hydroxylase activity	Catalysis of the reaction: formononetin + NADPH + O2 = 2'-hydroxyformononetin + NADP+ + H2O.	tmpzr1t_l9r_go_relaxed.owl	formononetin,NADPH:oxygen oxidoreductase (2'-hydroxylating)|isoflavone 2'-monooxygenase activity				MetaCyc:ISOFLAVONE-2-HYDROXYLASE-RXN|EC:1.14.14.89|RHEA:12388									molecular_function											owl:Class	
GO:0014051	biolink:NamedThing	gamma-aminobutyric acid secretion	The regulated release of gamma-aminobutyric acid by a cell or a tissue. The gamma-aminobutyric acid is the principal inhibitory neurotransmitter in the brain but is also found in several extraneural tissues.	tmpzr1t_l9r_go_relaxed.owl	GABA secretion													biological_process											owl:Class	
GO:0080170	biolink:NamedThing	hydrogen peroxide transmembrane transport	The process in which hydrogen peroxide is transported across a membrane.	tmpzr1t_l9r_go_relaxed.owl	hydrogen peroxide membrane transport					Note that this term is not intended for use in annotating lateral movement within membranes.		dhl	2010-09-23T05:12:14Z					biological_process											owl:Class	
GO:0055085	biolink:NamedThing	transmembrane transport	The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	membrane transport|ATP hydrolysis coupled transmembrane transport					Transmembrane transport is the transport of a solute across a lipid bilayer. Note that transport through the nuclear pore complex is not transmembrane because the nuclear membrane is a double membrane and is not traversed. For transport through the nuclear pore, consider instead the term 'nucleocytoplasmic transport ; GO:0006913' and its children. Note also that this term is not intended for use in annotating lateral movement within membranes.		tb	2015-10-21T13:22:47Z			GO:0090662		biological_process											owl:Class	
GO:0018355	biolink:NamedThing	protein-phosphoribosyl dephospho-coenzyme A linkage via O-(phosphoribosyl dephospho-coenzyme A)-L-serine	The formation of a protein-phosphoribosyl dephospho-coenzyme A linkage via O-(phosphoribosyl dephospho-coenzyme A)-L-serine.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0015827	biolink:NamedThing	tryptophan transport	The directed movement of tryptophan, 2-amino-3-(1H-indol-3-yl)propanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	L-tryptophan transport													biological_process											owl:Class	
GO:0046942	biolink:NamedThing	carboxylic acid transport	The directed movement of carboxylic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Carboxylic acids are organic acids containing one or more carboxyl (COOH) groups or anions (COO-).	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0035733	biolink:NamedThing	hepatic stellate cell activation	A change in the morphology or behavior of a hepatic stellate cell resulting from exposure to a cytokine, chemokine, hormone, cellular ligand or soluble factor.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-03-11T10:04:12Z					biological_process											owl:Class	
GO:0072537	biolink:NamedThing	fibroblast activation	A change in the morphology or behavior of a fibroblast resulting from exposure to an activating factor such as a cellular or soluble ligand.	tmpzr1t_l9r_go_relaxed.owl								mah	2011-01-14T04:35:08Z					biological_process											owl:Class	
GO:2001226	biolink:NamedThing	negative regulation of chloride transport	Any process that stops, prevents or reduces the frequency, rate or extent of chloride transport.	tmpzr1t_l9r_go_relaxed.owl								dph	2011-11-18T05:46:03Z					biological_process											owl:Class	
GO:1903792	biolink:NamedThing	negative regulation of anion transport	Any process that stops, prevents or reduces the frequency, rate or extent of anion transport.	tmpzr1t_l9r_go_relaxed.owl	downregulation of anion transport|inhibition of anion transport|down regulation of anion transport|down-regulation of anion transport							sl	2015-01-12T21:50:20Z					biological_process											owl:Class	
GO:0003105	biolink:NamedThing	negative regulation of glomerular filtration	Any process that stops, prevents, or reduces the frequency, rate or extent of glomerular filtration. Glomerular filtration is the processs whereby blood is filtered by the glomerulus into the renal tubule.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0048281	biolink:NamedThing	inflorescence morphogenesis	The process in which the anatomical structures of inflorescences are generated and organized. An inflorescence is the part of a seed plant body that is usually above ground and that can bear flowers.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0033797	biolink:NamedThing	selenate reductase activity	Catalysis of the reaction: 2 e(-) + 2 H(+) + selenate = H(2)O + selenite.	tmpzr1t_l9r_go_relaxed.owl	selenite:reduced acceptor oxidoreductase activity				EC:1.97.1.9|RHEA:14029|UM-BBD_reactionID:r0828|KEGG_REACTION:R07229|MetaCyc:RXN0-2101									molecular_function											owl:Class	
GO:0061235	biolink:NamedThing	mesenchymal stem cell maintenance involved in mesonephric nephron morphogenesis	The process in which an organism retains a population of mesenchymal stem cells that contributes to the shaping of a nephron in the mesonephros. A mesenchymal stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-08-19T02:57:11Z					biological_process											owl:Class	
GO:0072038	biolink:NamedThing	mesenchymal stem cell maintenance involved in nephron morphogenesis	The process in which an organism retains a population of mesenchymal stem cells that contributes to the shaping of a nephron. A mesenchymal stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-01-25T03:08:05Z					biological_process											owl:Class	
GO:1905873	biolink:NamedThing	positive regulation of protein localization to cell leading edge	Any process that activates or increases the frequency, rate or extent of protein localization to cell leading edge.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of protein localisation to cell leading edge|up regulation of protein localisation in cell leading edge|upregulation of protein localization to cell leading edge|positive regulation of protein localization in cell leading edge|positive regulation of protein localisation to cell leading edge|positive regulation of protein localisation in cell leading edge|up-regulation of protein localization in cell leading edge|activation of protein localisation to cell leading edge|upregulation of protein localisation in cell leading edge|up regulation of protein localization to cell leading edge|up regulation of protein localization in cell leading edge|up-regulation of protein localization to cell leading edge|activation of protein localization in cell leading edge|upregulation of protein localization in cell leading edge|activation of protein localisation in cell leading edge|upregulation of protein localisation to cell leading edge|up-regulation of protein localisation in cell leading edge|activation of protein localization to cell leading edge|up regulation of protein localisation to cell leading edge							sl	2017-01-27T19:35:13Z					biological_process											owl:Class	
GO:1903829	biolink:NamedThing	positive regulation of protein localization	Any process that activates or increases the frequency, rate or extent of a protein localization.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of cellular protein localisation|upregulation of cellular protein localization|up regulation of cellular protein localization|up regulation of cellular protein localisation|positive regulation of cellular protein localization|up-regulation of cellular protein localization|up-regulation of cellular protein localisation|upregulation of cellular protein localisation	https://github.com/geneontology/go-ontology/issues/22021						jl	2015-01-20T14:32:33Z					biological_process											owl:Class	
GO:0003319	biolink:NamedThing	cardioblast migration to the midline involved in heart rudiment formation	The orderly movement of a cardioblast toward the midline that contributes to the initial appearance of the heart rudiment.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-10-27T09:21:36Z					biological_process											owl:Class	
GO:0003318	biolink:NamedThing	cell migration to the midline involved in heart development	The orderly movement of a cell toward the midline that contributes to the progression of the heart over time.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-10-27T09:15:43Z					biological_process											owl:Class	
GO:0014866	biolink:NamedThing	skeletal myofibril assembly	The process whose specific outcome is the progression of the skeletal myofibril over time, from its formation to the mature structure. A skeletal myofibril is a myofibril specific to skeletal muscle cells.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0106265	biolink:NamedThing	THPH synthase activity	Catalysis of the reaction: 3 H+ + hexanoyl-CoA + 3 malonyl-CoA = 2,4,6-trihydroxyphenylhexan-1-one + 3 CO2 + 4 CoA.	tmpzr1t_l9r_go_relaxed.owl	polyketide syntase				RHEA:64352			hjd	2020-06-02T18:05:33Z					molecular_function											owl:Class	
GO:0016740	biolink:NamedThing	transferase activity	Catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-8868783|Reactome:R-HSA-1483186|Reactome:R-HSA-1483089|Reactome:R-HSA-5668414|EC:2.-.-.-									molecular_function											owl:Class	
GO:1902063	biolink:NamedThing	betaine aldehyde biosynthetic process	The chemical reactions and pathways resulting in the formation of betaine aldehyde.	tmpzr1t_l9r_go_relaxed.owl	betaine aldehyde synthesis|betaine aldehyde anabolism|betaine aldehyde formation|betaine aldehyde biosynthesis							di	2013-04-16T12:07:17Z					biological_process											owl:Class	
GO:1901576	biolink:NamedThing	organic substance biosynthetic process	The chemical reactions and pathways resulting in the formation of an organic substance, any molecular entity containing carbon.	tmpzr1t_l9r_go_relaxed.owl	organic molecular entity biosynthesis|organic substance formation|organic substance synthesis|organic molecular entity formation|organic substance biosynthesis|organic molecular entity synthesis|organic molecular entity biosynthetic process|organic substance anabolism|organic molecular entity anabolism							pr	2012-11-05T11:04:40Z					biological_process											owl:Class	
GO:1990172	biolink:NamedThing	G protein-coupled receptor catabolic process	The chemical reactions and pathways resulting in the breakdown of a G protein-coupled receptor.	tmpzr1t_l9r_go_relaxed.owl	G-protein coupled receptor catabolic process							sp	2013-08-22T10:16:58Z					biological_process											owl:Class	
GO:0140288	biolink:NamedThing	GBAF complex	A SWI/SNF subcomplex that incorporates two mutually exclusive paralogs, GLTSCR1 (glioma tumor suppressor candidate region gene 1) or GLTSCR1L (GLTSCR1-like), BRD9 (bromodomain-containing 9) and the BAF subunits BAF155, BAF60, SS18, BAF53a, and BRG1/BRM.	tmpzr1t_l9r_go_relaxed.owl								pg	2018-11-20T09:13:52Z					cellular_component											owl:Class	
GO:1903988	biolink:NamedThing	iron ion export across plasma membrane	The directed movement of iron ions from inside of a cell, across the plasma membrane and into the extracellular region.	tmpzr1t_l9r_go_relaxed.owl	iron(2+) export|iron cation export|ferrous iron export|ferrous iron export across plasma membrane					An example of this is mouse ferroportin (symbol Slc40a1, UniProtKB identifier: Q9JHI9).		rl	2014-09-03T13:01:37Z			GO:1903414		biological_process											owl:Class	
GO:0070839	biolink:NamedThing	metal ion export	The directed movement of metal cations, out of a cell or organelle.	tmpzr1t_l9r_go_relaxed.owl	divalent metal ion export							mah	2009-07-31T01:07:46Z					biological_process											owl:Class	
GO:0030624	biolink:NamedThing	U6atac snRNA binding	Binding to a U6atac small nuclear RNA (U6atac snRNA).	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0019756	biolink:NamedThing	cyanogenic glycoside biosynthetic process	The chemical reactions and pathways resulting in the formation of cyanogenic glycosides, any glycoside containing a cyano group that is released as hydrocyanic acid on acid hydrolysis; such compounds occur in the kernels of various fruits.	tmpzr1t_l9r_go_relaxed.owl	cyanogenic glycoside formation|cyanogenic glycoside synthesis|cyanogenic glycoside anabolism|cyanogenic glycoside biosynthesis													biological_process											owl:Class	
GO:0018259	biolink:NamedThing	RNA-protein covalent cross-linking via peptidyl-serine	The formation of a covalent cross-link between RNA and a peptidyl-serine residue by the formation of O-(phospho-5'-5NA)-L-serine.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0213									biological_process											owl:Class	
GO:0018144	biolink:NamedThing	RNA-protein covalent cross-linking	The formation of a covalent cross-link between RNA and a protein.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0050168	biolink:NamedThing	pentanamidase activity	Catalysis of the reaction: H(2)O + pentanamide = NH(4)(+) + valerate.	tmpzr1t_l9r_go_relaxed.owl	valeramidase activity|pentanamide amidohydrolase activity				RHEA:10000|KEGG_REACTION:R02938|EC:3.5.1.50|MetaCyc:PENTANAMIDASE-RXN									molecular_function											owl:Class	
GO:1904222	biolink:NamedThing	positive regulation of serine C-palmitoyltransferase activity	Any process that activates or increases the frequency, rate or extent of serine C-palmitoyltransferase activity.	tmpzr1t_l9r_go_relaxed.owl	up regulation of serine C-palmitoyltransferase activity|upregulation of acyl-CoA:serine C-2 acyltransferase decarboxylating|up regulation of 3-oxosphinganine synthetase activity|up-regulation of acyl-CoA:serine C-2 acyltransferase decarboxylating|up-regulation of 3-oxosphinganine synthetase activity|upregulation of SPT|up regulation of palmitoyl-CoA:L-serine C-palmitoyltransferase (decarboxylating) activity|activation of serine C-palmitoyltransferase activity|activation of acyl-CoA:serine C-2 acyltransferase decarboxylating|up-regulation of palmitoyl-CoA:L-serine C-palmitoyltransferase (decarboxylating) activity|positive regulation of acyl-CoA:serine C-2 acyltransferase decarboxylating|up regulation of SPT|positive regulation of SPT|upregulation of palmitoyl-CoA:L-serine C-palmitoyltransferase (decarboxylating) activity|upregulation of serine C-palmitoyltransferase activity|activation of SPT|activation of 3-oxosphinganine synthetase activity|up-regulation of SPT|activation of palmitoyl-CoA:L-serine C-palmitoyltransferase (decarboxylating) activity|up regulation of acyl-CoA:serine C-2 acyltransferase decarboxylating|up-regulation of serine C-palmitoyltransferase activity|positive regulation of 3-oxosphinganine synthetase activity|positive regulation of palmitoyl-CoA:L-serine C-palmitoyltransferase (decarboxylating) activity|upregulation of 3-oxosphinganine synthetase activity					Serinc proteins form a complex with serine and sphingolipid biosynthesis enzymes and regulates their activity through regulation of the substrate availability		rl	2015-05-15T08:27:45Z					biological_process											owl:Class	
GO:0050467	biolink:NamedThing	pentalenene synthase activity	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = diphosphate + pentalenene.	tmpzr1t_l9r_go_relaxed.owl	2-trans,6-trans-farnesyldiphosphate diphosphate-lyase (cyclizing, pentalenene-forming)|2-trans,6-trans-farnesyl-diphosphate diphosphate-lyase (cyclizing, pentalenene-forming)|pentalenene synthetase activity				MetaCyc:PENTALENENE-SYNTHASE-RXN|RHEA:18081|KEGG_REACTION:R02305|EC:4.2.3.7									molecular_function											owl:Class	
GO:0006066	biolink:NamedThing	alcohol metabolic process	The chemical reactions and pathways involving alcohols, any of a class of compounds containing one or more hydroxyl groups attached to a saturated carbon atom.	tmpzr1t_l9r_go_relaxed.owl	alcohol metabolism													biological_process											owl:Class	
GO:1904089	biolink:NamedThing	negative regulation of neuron apoptotic process by negative regulation of transcription from RNA polymerase II promoter	A negative regulation of transcription from RNA polymerase II promoter that results in negative regulation of neuron apoptotic process.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of neuron apoptosis by negative regulation of transcription from RNA polymerase II promoter|negative regulation of programmed cell death, neurons by negative regulation of transcription from RNA polymerase II promoter							pr	2015-03-25T21:04:51Z					biological_process											owl:Class	
GO:0043524	biolink:NamedThing	negative regulation of neuron apoptotic process	Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process in neurons.	tmpzr1t_l9r_go_relaxed.owl	inhibition of neuron apoptosis|downregulation of neuron apoptosis|negative regulation of neuron apoptosis|down regulation of neuron apoptosis|neuron survival|down-regulation of neuron apoptosis|negative regulation of programmed cell death, neurons													biological_process											owl:Class	
GO:0002426	biolink:NamedThing	immunoglobulin production in mucosal tissue	The synthesis and release of immunoglobulin in the mucosal tissue.	tmpzr1t_l9r_go_relaxed.owl	antibody production in mucosal tissue					Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.								biological_process											owl:Class	
GO:0002381	biolink:NamedThing	immunoglobulin production involved in immunoglobulin-mediated immune response	The appearance of immunoglobulin due to biosynthesis or secretion following a cellular stimulus during an immune response, resulting in an increase in its intracellular or extracellular levels.	tmpzr1t_l9r_go_relaxed.owl	immunoglobulin production during immune response|antibody secretion during immune response|immunoglobulin biosynthetic process involved in immune response|antibody production during immune response|immunoglobulin secretion involved in immune response|immunoglobulin production involved in immune response|immunoglobulin production involved in immunoglobulin mediated immune response					Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.						GO:0002380|GO:0002379		biological_process											owl:Class	
GO:0008970	biolink:NamedThing	phospholipase A1 activity	Catalysis of the reaction: phosphatidylcholine + H2O = 2-acylglycerophosphocholine + a carboxylate.	tmpzr1t_l9r_go_relaxed.owl	phosphatidylcholine 1-acylhydrolase activity				Reactome:R-HSA-1482847|MetaCyc:PHOSPHOLIPASE-A1-RXN|Reactome:R-HSA-1482892|EC:3.1.1.32|RHEA:18689|Reactome:R-HSA-1482827|Reactome:R-HSA-1482920|Reactome:R-HSA-1482828|Reactome:R-HSA-1482932|Reactome:R-HSA-5694485|Reactome:R-HSA-1482862									molecular_function											owl:Class	
GO:0042888	biolink:NamedThing	molybdenum ion transmembrane transporter activity	Enables the transfer of molybdenum (Mo) ions from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0046915	biolink:NamedThing	transition metal ion transmembrane transporter activity	Enables the transfer of transition metal ions from one side of a membrane to the other. A transition metal is an element whose atom has an incomplete d-subshell of extranuclear electrons, or which gives rise to a cation or cations with an incomplete d-subshell. Transition metals often have more than one valency state. Biologically relevant transition metals include vanadium, manganese, iron, copper, cobalt, nickel, molybdenum and silver.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0048092	biolink:NamedThing	negative regulation of male pigmentation	Any process that stops, prevents, or reduces the frequency, rate or extent of establishment of a pattern of pigment in males.	tmpzr1t_l9r_go_relaxed.owl	inhibition of male pigmentation|down-regulation of male pigmentation|downregulation of male pigmentation|down regulation of male pigmentation													biological_process											owl:Class	
GO:0055111	biolink:NamedThing	ingression involved in gastrulation with mouth forming second	The migration of individual cells into the embryo involved in deuterostomic gastrulation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0042074	biolink:NamedThing	cell migration involved in gastrulation	The migration of individual cells within the blastocyst to help establish the multi-layered body plan of the organism (gastrulation). For example, the migration of cells from the surface to the interior of the embryo (ingression).	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1905193	biolink:NamedThing	negative regulation of chloroplast fission	Any process that stops, prevents or reduces the frequency, rate or extent of chloroplast fission.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of chloroplast fission|down-regulation of chloroplast division|inhibition of chloroplast division|negative regulation of chloroplast division|down regulation of chloroplast division|downregulation of chloroplast division|inhibition of chloroplast fission|downregulation of chloroplast fission|down regulation of chloroplast fission					Any process that modulates the rate, frequency or extent of chloroplast fission. Chloroplast fission is the division of a chloroplast within a cell to form two or more separate chloroplast compartments.		lr	2016-05-10T19:07:43Z					biological_process											owl:Class	
GO:0002931	biolink:NamedThing	response to ischemia	Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a inadequate blood supply.	tmpzr1t_l9r_go_relaxed.owl						Ischemia always results in hypoxia; however, hypoxia can occur without ischemia.		hjd	2012-04-20T02:57:51Z					biological_process											owl:Class	
GO:0006950	biolink:NamedThing	response to stress	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).	tmpzr1t_l9r_go_relaxed.owl	response to biotic stress|response to abiotic stress					Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.								biological_process											owl:Class	
GO:0032257	biolink:NamedThing	maintenance of dense core granule location	Any process in which a dense core granule is maintained in a specific location within a cell and prevented from moving elsewhere.	tmpzr1t_l9r_go_relaxed.owl	maintenance of dense core granule localization|maintenance of dense core vesicle location													biological_process											owl:Class	
GO:0032255	biolink:NamedThing	maintenance of secretory granule location	Any process in which a secretory granule is maintained in a specific location within a cell and prevented from moving elsewhere.	tmpzr1t_l9r_go_relaxed.owl	maintenance of secretory granule localization													biological_process											owl:Class	
GO:0102873	biolink:NamedThing	1-18:1-2-16:0-digalactosyldiacylglycerol desaturase activity	Catalysis of the reaction: 1-18:1-2-16:0-digalactosyldiacylglycerol + O2 + a reduced electron acceptor <=> 1-18:2-2-16:0-digalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor.	tmpzr1t_l9r_go_relaxed.owl					EC:1.14.19.23|MetaCyc:RXN-8363									molecular_function											owl:Class	
GO:1904146	biolink:NamedThing	positive regulation of meiotic cell cycle process involved in oocyte maturation	Any process that activates or increases the frequency, rate or extent of meiotic cell cycle process involved in oocyte maturation.	tmpzr1t_l9r_go_relaxed.owl	up regulation of meiotic cell cycle process involved in oocyte maturation|upregulation of meiotic cell cycle process involved in oocyte maturation|up-regulation of meiotic cell cycle process involved in oocyte maturation|activation of meiotic cell cycle process involved in oocyte maturation							tb	2015-04-14T15:59:28Z					biological_process											owl:Class	
GO:1903538	biolink:NamedThing	regulation of meiotic cell cycle process involved in oocyte maturation	Any process that modulates the frequency, rate or extent of meiotic cell cycle process involved in oocyte maturation.	tmpzr1t_l9r_go_relaxed.owl	regulation of meiosis involved in oocyte maturation							pr	2014-10-09T10:52:38Z					biological_process											owl:Class	
GO:0045332	biolink:NamedThing	phospholipid translocation	The movement of a phospholipid molecule from one leaflet of a membrane bilayer to the opposite leaflet.	tmpzr1t_l9r_go_relaxed.owl	flippase|phospholipid scrambling					Note that this term describes the transbilayer motion of individual phospholipid molecules, and should not be confused with 'phospholipid scrambling ; GO:0017121'.								biological_process											owl:Class	
GO:0015914	biolink:NamedThing	phospholipid transport	The directed movement of phospholipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Phospholipids are any lipids containing phosphoric acid as a mono- or diester.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0006618	biolink:NamedThing	SRP-dependent cotranslational protein targeting to membrane, signal sequence processing	The removal of the signal peptide from a nascent protein during cotranslational membrane targeting.	tmpzr1t_l9r_go_relaxed.owl	SRP-dependent cotranslational membrane targeting, signal sequence processing|SRP-dependent cotranslational protein-membrane targeting, signal sequence processing|signal sequence processing during SRP-dependent cotranslational protein targeting to membrane													biological_process											owl:Class	
GO:0006465	biolink:NamedThing	signal peptide processing	The proteolytic removal of a signal peptide from a protein during or after transport to a specific location in the cell.	tmpzr1t_l9r_go_relaxed.owl	leader peptide processing													biological_process											owl:Class	
GO:0043173	biolink:NamedThing	nucleotide salvage	Any process which produces a nucleotide, a compound consisting of a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the glycose moiety, from derivatives of it without de novo synthesis.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Nucleotide_salvage									biological_process											owl:Class	
GO:0018889	biolink:NamedThing	2-chloro-N-isopropylacetanilide metabolic process	The chemical reactions and pathways involving 2-chloro-N-isopropylacetanilide, an acylanide herbicide widely used to protect corn, onion, cabbage, rose bushes, and ornamental plants.	tmpzr1t_l9r_go_relaxed.owl	2-chloro-N-isopropylacetanilide metabolism|propachlor metabolism|propachlor metabolic process				UM-BBD_pathwayID:ppc									biological_process											owl:Class	
GO:2000227	biolink:NamedThing	negative regulation of pancreatic A cell differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of pancreatic A cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of pancreatic alpha cell differentiation							mah	2010-11-09T03:43:40Z					biological_process											owl:Class	
GO:2000226	biolink:NamedThing	regulation of pancreatic A cell differentiation	Any process that modulates the frequency, rate or extent of pancreatic A cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	regulation of pancreatic alpha cell differentiation							mah	2010-11-09T03:43:37Z					biological_process											owl:Class	
GO:0047950	biolink:NamedThing	glutathione oxidase activity	Catalysis of the reaction: 2 glutathione + O(2) = glutathione disulfide + H(2)O(2).	tmpzr1t_l9r_go_relaxed.owl	glutathione:oxygen oxidoreductase activity				KEGG_REACTION:R00120|MetaCyc:GLUTATHIONE-OXIDASE-RXN|RHEA:24112|EC:1.8.3.3									molecular_function											owl:Class	
GO:0016670	biolink:NamedThing	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which a sulfur-containing group acts as a hydrogen or electron donor and reduces oxygen.	tmpzr1t_l9r_go_relaxed.owl	oxidoreductase activity, acting on sulphur group of donors, oxygen as acceptor				EC:1.8.3.-									molecular_function											owl:Class	
GO:0035280	biolink:NamedThing	miRNA loading onto RISC involved in gene silencing by miRNA	The transfer of a microRNA (miRNA) strand from a miRNA:miRNA duplex onto the RNA-initiated silencing complex (RISC).	tmpzr1t_l9r_go_relaxed.owl	microRNA loading onto RISC involved in gene silencing by microRNA|miRNA-mediated gene silencing, miRNA loading onto RISC|gene silencing by miRNA, miRNA loading onto RISC|miRISC assembly													biological_process											owl:Class	
GO:1904552	biolink:NamedThing	regulation of chemotaxis to arachidonic acid	Any process that modulates the frequency, rate or extent of chemotaxis to arachidonic acid.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-08-13T21:08:14Z					biological_process											owl:Class	
GO:0031247	biolink:NamedThing	actin rod assembly	The assembly of actin rods, a cellular structure consisting of parallel, hexagonally arranged actin tubules.	tmpzr1t_l9r_go_relaxed.owl	actin rod formation													biological_process											owl:Class	
GO:0051017	biolink:NamedThing	actin filament bundle assembly	The assembly of actin filament bundles; actin filaments are on the same axis but may be oriented with the same or opposite polarities and may be packed with different levels of tightness.	tmpzr1t_l9r_go_relaxed.owl	actin cable formation|actin bundling activity|actin cable assembly											GO:0045011		biological_process											owl:Class	
GO:0036184	biolink:NamedThing	asperthecin biosynthetic process	The chemical reactions and pathways resulting in the formation of asperthecin, an anthraquinone pigment obtained from the mould Aspergillus nidulans.	tmpzr1t_l9r_go_relaxed.owl	asperthecin formation|asperthecin synthesis|asperthecin biosynthesis							bf	2012-04-16T11:36:56Z					biological_process											owl:Class	
GO:0099593	biolink:NamedThing	endocytosed synaptic vesicle to endosome fusion	Fusion of an endocytosed synaptic vesicle with an endosome.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0016189	biolink:NamedThing	synaptic vesicle to endosome fusion	Fusion of a synaptic vesicle with an endosome.	tmpzr1t_l9r_go_relaxed.owl						This covers fusion of synaptic vesicles trafficked to the synapse as well as fusion of endocytosed vesicles as part of recycling.  It is there for not  part of the synaptic vesicle cycle.								biological_process											owl:Class	
GO:0060533	biolink:NamedThing	bronchus cartilage morphogenesis	The process in which the bronchus cartilage is generated and organized. The bronchus cartilage is the connective tissue of the portion of the airway that connects to the lungs.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-04-10T08:47:41Z					biological_process											owl:Class	
GO:0060536	biolink:NamedThing	cartilage morphogenesis	The process in which the anatomical structures of cartilage are generated and organized.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-04-10T09:13:27Z					biological_process											owl:Class	
GO:0036378	biolink:NamedThing	calcitriol biosynthetic process from calciol	Conversion of vitamin D3 from its largely inactive form (calciol, also called cholecalciferol) into a hormonally active form (calcitriol). Conversion requires 25-hydroxylation of calciol in the liver to form calcidiol, and subsequent 1,alpha-hydroxylation of calcidiol in the kidney to form calcitriol.	tmpzr1t_l9r_go_relaxed.owl	1alpha,25(OH)2D3 biosynthesis|1alpha,25-dihydroxycholecalciferol biosynthesis|calcitriol biosynthesis from calciol|1alpha,25-dihydroxyvitamin D3 biosynthesis|vitamin D3 activation							bf	2013-05-15T11:46:08Z					biological_process											owl:Class	
GO:0070640	biolink:NamedThing	vitamin D3 metabolic process	The chemical reactions and pathways involving vitamin D3, (3S,5Z,7E)-9,10-secocholesta-5,7,10(19)-trien-3-ol.	tmpzr1t_l9r_go_relaxed.owl	vitamin D3 metabolism|cholecalciferol metabolic process|calciol metabolic process							mah	2009-05-08T02:24:24Z					biological_process											owl:Class	
GO:1900323	biolink:NamedThing	positive regulation of maltotetraose transport	Any process that activates or increases the frequency, rate or extent of maltotetraose transport.	tmpzr1t_l9r_go_relaxed.owl	up regulation of maltotetraose transport|up-regulation of maltotetraose transport|activation of maltotetraose transport|upregulation of maltotetraose transport							tt	2012-04-06T01:45:54Z					biological_process											owl:Class	
GO:1900321	biolink:NamedThing	regulation of maltotetraose transport	Any process that modulates the frequency, rate or extent of maltotetraose transport.	tmpzr1t_l9r_go_relaxed.owl								tt	2012-04-06T01:45:36Z					biological_process											owl:Class	
GO:0110112	biolink:NamedThing	regulation of lipid transporter activity	Any process that modulates the frequency, rate, or extent of lipid transporter activity.	tmpzr1t_l9r_go_relaxed.owl								kmv	2018-07-06T18:53:55Z					biological_process											owl:Class	
GO:0072663	biolink:NamedThing	establishment of protein localization to peroxisome	The directed movement of a protein to a specific location in a peroxisome.	tmpzr1t_l9r_go_relaxed.owl	establishment of protein localisation to peroxisome							mah	2011-02-14T02:50:36Z					biological_process											owl:Class	
GO:0045273	biolink:NamedThing	respiratory chain complex II	A part of the respiratory chain, containing the four polypeptide subunits of succinate dehydrogenase, flavin-adenine dinucleotide and iron-sulfur. Catalyzes the oxidation of succinate by ubiquinone. Connects the TCA cycle with the respiratory chain.	tmpzr1t_l9r_go_relaxed.owl	electron transport complex II													cellular_component											owl:Class	
GO:0098803	biolink:NamedThing	respiratory chain complex	Any protein complex that is part of a respiratory chain.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0034077	biolink:NamedThing	butanediol metabolic process	The chemical reactions and pathways involving butanediol; the biologically relevant isomer is 2,3-butanediol, CH3CH(OH)CH(OH)CH3.	tmpzr1t_l9r_go_relaxed.owl	butanediol metabolism|butylene glycol metabolic process|butylene glycol metabolism													biological_process											owl:Class	
GO:1990811	biolink:NamedThing	MWP complex	A protein ternary complex that anchors microtubule minus ends to mitotic spindle pole bodies. The founding complex contains a microtubule anchoring protein (Msd1 in fission yeast), A WD-repeat Wdr8 family protein and and a minus end-directed kinesin.	tmpzr1t_l9r_go_relaxed.owl	Msd1-Wdr8-Pkl1 complex							vw	2015-07-24T13:34:31Z					cellular_component											owl:Class	
GO:0052128	biolink:NamedThing	positive energy taxis	The directed movement of a motile cell or organism towards a higher level of a physical stimulus involved in energy generation, such as light, oxygen, and oxidizable substrates.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0009453	biolink:NamedThing	energy taxis	The directed movement of a motile cell or organism in response to physical parameters involved in energy generation, such as light, oxygen, and oxidizable substrates.	tmpzr1t_l9r_go_relaxed.owl	taxis in response to energy source|energytaxis													biological_process											owl:Class	
GO:1902138	biolink:NamedThing	(-)-secoisolariciresinol biosynthetic process	The chemical reactions and pathways resulting in the formation of (-)-secoisolariciresinol.	tmpzr1t_l9r_go_relaxed.owl	(-)-secoisolariciresinol anabolism|(-)-secoisolariciresinol formation|(-)-secoisolariciresinol synthesis|(-)-secoisolariciresinol biosynthesis							ms	2013-05-21T08:50:29Z					biological_process											owl:Class	
GO:1903419	biolink:NamedThing	protein localization to cortical endoplasmic reticulum	A process in which a protein is transported to, or maintained in, a location within a cortical endoplasmic reticulum.	tmpzr1t_l9r_go_relaxed.owl	protein localisation to cortical endoplasmic reticulum|protein localization to cortical ER|protein localization in cortical endoplasmic reticulum|protein localisation in cortical endoplasmic reticulum							mah	2014-09-08T16:03:28Z					biological_process											owl:Class	
GO:1903420	biolink:NamedThing	protein localization to endoplasmic reticulum tubular network	A process in which a protein is transported to, or maintained in, a location within an endoplasmic reticulum tubular network.	tmpzr1t_l9r_go_relaxed.owl	protein localisation in endoplasmic reticulum tubular network|protein localization to tubular ER|protein localisation to endoplasmic reticulum tubular network|protein localization in endoplasmic reticulum tubular network							mah	2014-09-08T16:03:37Z					biological_process											owl:Class	
GO:1904913	biolink:NamedThing	regulation of establishment of protein-containing complex localization to telomere	Any process that modulates the frequency, rate or extent of establishment of the localization of a protein-containing macromolecular complex to a telomere.	tmpzr1t_l9r_go_relaxed.owl	regulation of establishment of macromolecular complex localisation to telomere|regulation of establishment of macromolecular complex localization to telomere							rph	2016-01-19T10:38:22Z					biological_process											owl:Class	
GO:1904061	biolink:NamedThing	positive regulation of locomotor rhythm	Any process that activates or increases the frequency, rate or extent of locomotor rhythm.	tmpzr1t_l9r_go_relaxed.owl	up regulation of locomotor rhythm|activation of circadian locomotor activity rhythm|up-regulation of locomotor rhythm|up-regulation of circadian locomotor activity rhythm|positive regulation of circadian locomotor activity rhythm|upregulation of locomotor rhythm|activation of locomotor rhythm|up regulation of circadian locomotor activity rhythm|upregulation of circadian locomotor activity rhythm							sl	2015-03-18T20:39:03Z					biological_process											owl:Class	
GO:0048520	biolink:NamedThing	positive regulation of behavior	Any process that activates or increases the frequency, rate or extent of behavior, the internally coordinated responses (actions or inactions) of whole living organisms (individuals or groups) to internal or external stimuli.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of behavior|stimulation of behavior|activation of behavior|up regulation of behavior|upregulation of behavior													biological_process											owl:Class	
GO:0032713	biolink:NamedThing	negative regulation of interleukin-4 production	Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-4 production.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of interleukin-4 biosynthetic process|inhibition of interleukin-4 production|negative regulation of interleukin-4 secretion|down regulation of interleukin-4 production|down-regulation of interleukin-4 production|negative regulation of IL-4 production|downregulation of interleukin-4 production							bc				GO:0150134|GO:0045403		biological_process											owl:Class	
GO:0032673	biolink:NamedThing	regulation of interleukin-4 production	Any process that modulates the frequency, rate, or extent of interleukin-4 production.	tmpzr1t_l9r_go_relaxed.owl	regulation of IL-4 production|regulation of interleukin-4 biosynthetic process|regulation of interleukin-4 secretion											GO:0045402|GO:0150133		biological_process											owl:Class	
GO:0075027	biolink:NamedThing	positive regulation of appressorium initiation	Any process that activates or increases the frequency, rate or extent of symbiont appressorium initiation.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of initiation of appressorium on or near host|positive regulation of appressorium initiation on or near host													biological_process											owl:Class	
GO:0075026	biolink:NamedThing	regulation of appressorium initiation	Any process that modulates the frequency, rate or extent of symbiont appressorium initiation.	tmpzr1t_l9r_go_relaxed.owl	regulation of appressorium initiation on or near host|regulation of initiation of appressorium on or near host					Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products from the symbiont involved in this process.								biological_process											owl:Class	
GO:0099033	biolink:NamedThing	anchored component of postsynaptic recycling endosome membrane	The component of the postsynaptic recycling endosome membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0046048	biolink:NamedThing	UDP metabolic process	The chemical reactions and pathways involving UDP, uridine (5'-)diphosphate.	tmpzr1t_l9r_go_relaxed.owl	UDP metabolism													biological_process											owl:Class	
GO:0009218	biolink:NamedThing	pyrimidine ribonucleotide metabolic process	The chemical reactions and pathways involving a pyrimidine ribonucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.	tmpzr1t_l9r_go_relaxed.owl	pyrimidine ribonucleotide metabolism													biological_process											owl:Class	
GO:1903456	biolink:NamedThing	positive regulation of androst-4-ene-3,17-dione biosynthetic process	Any process that activates or increases the frequency, rate or extent of androst-4-ene-3,17-dione biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	activation of androstenedione|activation of androst-4-ene-3,17-dione synthesis|up-regulation of androstenedione biosynthetic process|up regulation of androst-4-ene-3,17-dione biosynthetic process|up regulation of androst-4-ene-3,17-dione biosynthesis|positive regulation of androst-4-ene-3,17-dione biosynthesis|up-regulation of androst-4-ene-3,17-dione anabolism|positive regulation of androstenedione biosynthetic process|up regulation of androst-4-ene-3,17-dione formation|positive regulation of androst-4-ene-3,17-dione anabolism|upregulation of androstenedione biosynthetic process|up-regulation of androst-4-ene-3,17-dione biosynthetic process|up-regulation of androst-4-ene-3,17-dione formation|positive regulation of androst-4-ene-3,17-dione formation|activation of androst-4-ene-3,17-dione formation|up regulation of androst-4-ene-3,17-dione anabolism|upregulation of androst-4-ene-3,17-dione biosynthesis|up-regulation of androst-4-ene-3,17-dione biosynthesis|positive regulation of androst-4-ene-3,17-dione synthesis|activation of androst-4-ene-3,17-dione biosynthetic process|up regulation of androstenedione biosynthetic process|up-regulation of androst-4-ene-3,17-dione synthesis|activation of androst-4-ene-3,17-dione anabolism|up regulation of androst-4-ene-3,17-dione synthesis|upregulation of androst-4-ene-3,17-dione formation|activation of androst-4-ene-3,17-dione biosynthesis|upregulation of androst-4-ene-3,17-dione synthesis|upregulation of androst-4-ene-3,17-dione anabolism|upregulation of androst-4-ene-3,17-dione biosynthetic process							mr	2014-09-22T14:37:07Z					biological_process											owl:Class	
GO:0090049	biolink:NamedThing	regulation of cell migration involved in sprouting angiogenesis	Any process that modulates the frequency, rate or extent of cell migration involved in sprouting angiogenesis. Cell migration involved in sprouting angiogenesis is the orderly movement of endothelial cells into the extracellular matrix in order to form new blood vessels contributing to the process of sprouting angiogenesis.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-08-07T10:37:16Z					biological_process											owl:Class	
GO:2000201	biolink:NamedThing	negative regulation of ribosomal subunit export from nucleus	Any process that stops, prevents, or reduces the frequency, rate or extent of ribosomal subunit export from nucleus.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of ribosomal subunit-nucleus export|negative regulation of ribosomal subunit export from cell nucleus|negative regulation of ribosomal subunit transport from nucleus to cytoplasm|negative regulation of ribosomal subunit export out of nucleus|negative regulation of ribosome export from nucleus							mah	2010-10-26T10:44:32Z					biological_process											owl:Class	
GO:0097613	biolink:NamedThing	dinoflagellate epicone	The part of a dinoflagellate cell above the cingulum; also referred to as the anterior portion of a dinoflagellate cell. It is separated from the hypocone by the cingulum.	tmpzr1t_l9r_go_relaxed.owl	epitheca|episome|epicone					The term name refers to a taxonomic group to make the label unique with respect to similarly-named anatomical structures.		pr	2014-06-09T11:32:48Z					cellular_component											owl:Class	
GO:0055081	biolink:NamedThing	anion homeostasis	Any process involved in the maintenance of an internal steady state of anions within an organism or cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0022003	biolink:NamedThing	negative regulation of anterior neural cell fate commitment of the neural plate by fibroblast growth factor receptor signaling pathway	The series of molecular signals that stops, prevents or reduces the frequency or rate at which cell adopts an anterior neural cell fate, generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands.	tmpzr1t_l9r_go_relaxed.owl	fgf receptor signaling involved in negative regulation of anterior neural cell fate of the neural plate|fgf receptor signaling involved in downregulation of anterior neural cell fate of the neural plate|fgf receptor signalling involved in negative regulation of anterior neural cell fate of the neural plate|fgf receptor signaling involved in down-regulation of anterior neural cell fate of the neural plate|fgf receptor signaling involved in down regulation of anterior neural cell fate of the neural plate|fgf receptor signaling involved in inhibition of anterior neural cell fate of the neural plate													biological_process											owl:Class	
GO:0060825	biolink:NamedThing	fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation	The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands contributing to the anterior/posterior pattern of the neural plate.	tmpzr1t_l9r_go_relaxed.owl	fibroblast growth factor receptor signalling pathway involved in neural plate anterior/posterior pattern formation							dph	2009-08-11T01:40:03Z					biological_process											owl:Class	
GO:0106050	biolink:NamedThing	tRNA 2'-O-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing a 2'-O-nucleotide.	tmpzr1t_l9r_go_relaxed.owl								hjd	2017-08-11T20:30:31Z					molecular_function											owl:Class	
GO:0008175	biolink:NamedThing	tRNA methyltransferase activity	Catalysis of the transfer of a methyl group from a donor to a nucleoside residue in a tRNA molecule.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-6786567|Reactome:R-HSA-6782879|Reactome:R-HSA-6783473|Reactome:R-HSA-6782890|Reactome:R-HSA-6782881|Reactome:R-HSA-6786500									molecular_function											owl:Class	
GO:1904904	biolink:NamedThing	regulation of endothelial cell-matrix adhesion via fibronectin	Any process that modulates the frequency, rate or extent of endothelial cell-matrix adhesion via fibronectin.	tmpzr1t_l9r_go_relaxed.owl								bc	2016-01-19T10:23:01Z					biological_process											owl:Class	
GO:0001952	biolink:NamedThing	regulation of cell-matrix adhesion	Any process that modulates the frequency, rate or extent of attachment of a cell to the extracellular matrix.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0019550	biolink:NamedThing	glutamate catabolic process to aspartate	The chemical reactions and pathways resulting in the breakdown of glutamate into other compounds, including aspartate.	tmpzr1t_l9r_go_relaxed.owl	glutamate breakdown to aspartate|glutamate degradation to aspartate				MetaCyc:GLUTDEG-PWY									biological_process											owl:Class	
GO:0006531	biolink:NamedThing	aspartate metabolic process	The chemical reactions and pathways involving aspartate, the anion derived from aspartic acid, 2-aminobutanedioic acid.	tmpzr1t_l9r_go_relaxed.owl	aspartate metabolism													biological_process											owl:Class	
GO:0098911	biolink:NamedThing	regulation of ventricular cardiac muscle cell action potential	Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a ventricular cardiac muscle cell contributing to the regulation of its contraction.  This typically occurs via modulation of the activity or expression of voltage-gated ion channels.	tmpzr1t_l9r_go_relaxed.owl								tb	2011-11-10T07:59:36Z					biological_process											owl:Class	
GO:0015481	biolink:NamedThing	maltose transporting porin activity	Enables the transfer of maltose from one side of a membrane to the other. Maltose is the disaccharide 4-O-alpha-D-glucopyranosyl-D-glucopyranose, an intermediate in the enzymatic breakdown of glycogen and starch. This transporter is a porin so enables the energy independent passage of substances, sized less than 1000 Da, across a membrane. The transmembrane portions of porins consist exclusively of beta-strands which form a beta-barrel. They are found in the outer membranes of Gram-negative bacteria, mitochondria, plastids and possibly acid-fast Gram-positive bacteria.	tmpzr1t_l9r_go_relaxed.owl	maltoporin				Wikipedia:Maltoporin									molecular_function											owl:Class	
GO:0005363	biolink:NamedThing	maltose transmembrane transporter activity	Enables the transfer of maltose from one side of a membrane to the other. Maltose is the disaccharide 4-O-alpha-D-glucopyranosyl-D-glucopyranose, an intermediate in the enzymatic breakdown of glycogen and starch.	tmpzr1t_l9r_go_relaxed.owl	maltose porter activity				RHEA:33171							GO:0015581		molecular_function											owl:Class	
GO:0034207	biolink:NamedThing	steroid acetylation	The addition of an acetyl group to a steroid molecule. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0030258	biolink:NamedThing	lipid modification	The covalent alteration of one or more fatty acids in a lipid, resulting in a change in the properties of the lipid.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0031974	biolink:NamedThing	membrane-enclosed lumen	The enclosed volume within a sealed membrane or between two sealed membranes. Encompasses the volume enclosed by the membranes of a particular organelle, e.g. endoplasmic reticulum lumen, or the space between the two lipid bilayers of a double membrane surrounding an organelle, e.g. nuclear envelope lumen.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0050325	biolink:NamedThing	tauropine dehydrogenase activity	Catalysis of the reaction: H(2)O + NAD(+) + tauropine = H(+) + NADH + pyruvate + taurine.	tmpzr1t_l9r_go_relaxed.owl	N2-(D-1-carboxyethyl)taurine:NAD+ oxidoreductase (taurine-forming)|2-N-(D-1-carboxyethyl)taurine:NAD+ oxidoreductase (taurine-forming)				RHEA:12580|KEGG_REACTION:R01683|EC:1.5.1.23|MetaCyc:TAUROPINE-DEHYDROGENASE-RXN									molecular_function											owl:Class	
GO:0031531	biolink:NamedThing	thyrotropin-releasing hormone receptor binding	Binding to a receptor for thyrotropin-releasing hormone, a tripeptide hormone that is produced by the hypothalamus and stimulates the release of thyroid-stimulating hormone (TSH) and prolactin by the anterior pituitary.	tmpzr1t_l9r_go_relaxed.owl	thyrotropin releasing hormone receptor binding|thyrotropin-releasing hormone receptor ligand											GO:0031888		molecular_function											owl:Class	
GO:0051428	biolink:NamedThing	peptide hormone receptor binding	Binding to a receptor for a peptide hormone.	tmpzr1t_l9r_go_relaxed.owl	polypeptide hormone receptor binding													molecular_function											owl:Class	
GO:0042721	biolink:NamedThing	TIM22 mitochondrial import inner membrane insertion complex	A multi-subunit complex embedded in the mitochondrial inner membrane that mediates the inner membrane insertion of multi-transmembrane spanning proteins that contain internal targeting elements. In yeast cells, TIM22 is a 300-kDa complex, consisting of four membrane integral subunits, Tim22, Tim54, Tim18 and Sdh3, and a peripheral chaperone complex consisting of the small TIM proteins, Tim9-Tim10-Tim12.	tmpzr1t_l9r_go_relaxed.owl	Tim22 complex|mitochondrial protein translocase complex|mitochondrial inner membrane protein insertion complex													cellular_component											owl:Class	
GO:0070376	biolink:NamedThing	regulation of ERK5 cascade	Any process that modulates the frequency, rate or extent of signal transduction mediated by the ERK5 cascade.	tmpzr1t_l9r_go_relaxed.owl	regulation of BMK cascade|regulation of ERK5 signaling pathway|regulation of BMK signalling pathway|regulation of BMK1 cascade|regulation of MAPK7 cascade|regulation of BMK signaling pathway													biological_process											owl:Class	
GO:0070981	biolink:NamedThing	L-asparagine biosynthetic process	The chemical reactions and pathways resulting in the formation of asparagine, (2S)-2-amino-3-carbamoylpropanoic acid.	tmpzr1t_l9r_go_relaxed.owl	L-asparagine formation|L-asparagine anabolism|L-asparagine biosynthesis|L-asparagine synthesis							mah	2009-10-27T12:59:42Z					biological_process											owl:Class	
GO:0043604	biolink:NamedThing	amide biosynthetic process	The chemical reactions and pathways resulting in the formation of an amide, any derivative of an oxoacid in which an acidic hydroxy group has been replaced by an amino or substituted amino group.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1901752	biolink:NamedThing	leukotriene A4 catabolic process	The chemical reactions and pathways resulting in the breakdown of leukotriene A4.	tmpzr1t_l9r_go_relaxed.owl	leukotriene A4 breakdown|leukotriene A4 catabolism|leukotriene A4 degradation							yaf	2013-01-14T11:05:04Z					biological_process											owl:Class	
GO:0046700	biolink:NamedThing	heterocycle catabolic process	The chemical reactions and pathways resulting in the breakdown of heterocyclic compounds, those with a cyclic molecular structure and at least two different atoms in the ring (or rings).	tmpzr1t_l9r_go_relaxed.owl	heterocycle catabolism|heterocycle degradation|heterocycle breakdown													biological_process											owl:Class	
GO:0099029	biolink:NamedThing	anchored component of presynaptic active zone membrane	The component of the presynaptic active zone membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:1905023	biolink:NamedThing	positive regulation of threonine-tRNA ligase activity	Any process that activates or increases the frequency, rate or extent of threonine-tRNA ligase activity.	tmpzr1t_l9r_go_relaxed.owl	upregulation of threonyl-tRNA synthetase activity|up regulation of TRS|upregulation of threonine translase activity|upregulation of TRS|up regulation of threonyl-transfer ribonucleic acid synthetase activity|upregulation of threonyl-transfer ribonucleic acid synthetase activity|upregulation of threonyl-transfer ribonucleate synthetase activity|up-regulation of threonine-tRNA ligase activity|positive regulation of threonine translase activity|up regulation of threonyl-transfer RNA synthetase activity|activation of threonine-tRNA ligase activity|up regulation of threonine translase activity|up-regulation of threonine translase activity|up-regulation of L-threonine:tRNAThr ligase (AMP-forming)|positive regulation of threonyl-transfer ribonucleic acid synthetase activity|activation of threonyl ribonucleic synthetase activity|positive regulation of threonyl-transfer ribonucleate synthetase activity|up regulation of threonine-transfer ribonucleate synthetase activity|activation of threonyl-tRNA synthetase activity|up regulation of threonyl-tRNA synthetase activity|upregulation of threonine-tRNA ligase activity|up-regulation of TRS|activation of threonine translase activity|activation of threonine-transfer ribonucleate synthetase activity|up-regulation of threonyl-transfer RNA synthetase activity|positive regulation of threonine-transfer ribonucleate synthetase activity|positive regulation of TRS|up regulation of threonyl ribonucleic synthetase activity|activation of threonyl-transfer RNA synthetase activity|upregulation of threonyl-transfer RNA synthetase activity|positive regulation of threonyl-transfer RNA synthetase activity|upregulation of threonyl ribonucleic synthetase activity|up regulation of threonyl-transfer ribonucleate synthetase activity|activation of TRS|positive regulation of threonyl ribonucleic synthetase activity|activation of threonyl-transfer ribonucleic acid synthetase activity|up-regulation of threonyl-transfer ribonucleic acid synthetase activity|up regulation of L-threonine:tRNAThr ligase (AMP-forming)|activation of L-threonine:tRNAThr ligase (AMP-forming)|positive regulation of L-threonine:tRNAThr ligase (AMP-forming)|up-regulation of threonyl-tRNA synthetase activity|upregulation of threonine-transfer ribonucleate synthetase activity|up-regulation of threonyl ribonucleic synthetase activity|activation of threonyl-transfer ribonucleate synthetase activity|up regulation of threonine-tRNA ligase activity|up-regulation of threonine-transfer ribonucleate synthetase activity|upregulation of L-threonine:tRNAThr ligase (AMP-forming)|positive regulation of threonyl-tRNA synthetase activity|up-regulation of threonyl-transfer ribonucleate synthetase activity							sl	2016-03-03T19:12:41Z					biological_process											owl:Class	
GO:1901774	biolink:NamedThing	lincomycin biosynthetic process	The chemical reactions and pathways resulting in the formation of lincomycin.	tmpzr1t_l9r_go_relaxed.owl	lincomycin biosynthesis|lincomycin formation|lincomycin anabolism|lincomycin synthesis							yaf	2013-01-15T11:54:01Z					biological_process											owl:Class	
GO:0033384	biolink:NamedThing	geranyl diphosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of geranyl diphosphate.	tmpzr1t_l9r_go_relaxed.owl	geranyl diphosphate anabolism|geranyldiphosphate biosynthetic process|geranyl diphosphate biosynthesis|geranyl diphosphate formation|geranyl diphosphate synthesis				MetaCyc:PWY-5122									biological_process											owl:Class	
GO:0016114	biolink:NamedThing	terpenoid biosynthetic process	The chemical reactions and pathways resulting in the formation of terpenoids, any member of a class of compounds characterized by an isoprenoid chemical structure.	tmpzr1t_l9r_go_relaxed.owl	terpenoid synthesis|terpenoid anabolism|terpenoid formation|terpenoid biosynthesis				Wikipedia:Terpenoid									biological_process											owl:Class	
GO:0000445	biolink:NamedThing	THO complex part of transcription export complex	The THO complex when it is part of the TREX (TRanscription EXport) complex that is involved in coupling transcription to export of mRNAs to the cytoplasm. In S. cerevisiae, it is composed of four subunits: Hpr1, Tho2, Thp1, and Mft1, while the human complex is composed of 7 subunits.	tmpzr1t_l9r_go_relaxed.owl	THO complex part of TREX complex													cellular_component											owl:Class	
GO:0000347	biolink:NamedThing	THO complex	The THO complex is a nuclear complex that is required for transcription elongation through genes containing tandemly repeated DNA sequences. The THO complex is also part of the TREX (TRanscription EXport) complex that is involved in coupling transcription to export of mRNAs to the cytoplasm. In S. cerevisiae, it is composed of four subunits: Hpr1p, Tho2p, Thp1p, and Mft1p, while the human complex is composed of 7 subunits.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0036000	biolink:NamedThing	mucocyst	A small subcellular vesicle, surrounded by a membrane, in the pellicle of ciliate protozoans that discharges a mucus-like secretion.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-09-06T01:32:17Z					cellular_component											owl:Class	
GO:0030141	biolink:NamedThing	secretory granule	A small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion. Secretory granules move towards the periphery of the cell and upon stimulation, their membranes fuse with the cell membrane, and their protein load is exteriorized. Processing of the contained protein may take place in secretory granules.	tmpzr1t_l9r_go_relaxed.owl	secretory vesicle					Note that the term 'secretory vesicle' is sometimes used in this sense, but can also mean 'transport vesicle ; GO:0030133'.								cellular_component											owl:Class	
GO:0071307	biolink:NamedThing	cellular response to vitamin K	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin K stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-12-10T04:36:09Z					biological_process											owl:Class	
GO:0061337	biolink:NamedThing	cardiac conduction	Transfer of an organized electrical impulse across the heart to coordinate the contraction of cardiac muscles. The process begins with generation of an action potential (in the sinoatrial node (SA) in humans) and ends with a change in the rate, frequency, or extent of the contraction of the heart muscles.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-09-29T08:46:05Z					biological_process											owl:Class	
GO:0008016	biolink:NamedThing	regulation of heart contraction	Any process that modulates the frequency, rate or extent of heart contraction. Heart contraction is the process in which the heart decreases in volume in a characteristic way to propel blood through the body.	tmpzr1t_l9r_go_relaxed.owl	regulation of cardiac contraction													biological_process											owl:Class	
GO:0004855	biolink:NamedThing	xanthine oxidase activity	Catalysis of the reaction: xanthine + H2O + O2 = urate + hydrogen peroxide.	tmpzr1t_l9r_go_relaxed.owl	xanthine:O2 oxidoreductase activity|schardinger enzyme|xanthine:O(2) oxidoreductase activity|xanthine:xanthine oxidase activity|xanthine:oxygen oxidoreductase activity|Schardinger enzyme activity|hypoxanthine-xanthine oxidase activity|xanthine oxidoreductase activity				Reactome:R-HSA-74258|EC:1.17.3.2|UM-BBD_enzymeID:e0781|RHEA:21132|Reactome:R-HSA-74247|MetaCyc:XANTHINE-OXIDASE-RXN									molecular_function											owl:Class	
GO:0016727	biolink:NamedThing	oxidoreductase activity, acting on CH or CH2 groups, oxygen as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which a CH2 group acts as a hydrogen or electron donor and reduces an oxygen molecule.	tmpzr1t_l9r_go_relaxed.owl					EC:1.17.3.-									molecular_function											owl:Class	
GO:0050628	biolink:NamedThing	2-oxopropyl-CoM reductase (carboxylating) activity	Catalysis of the reaction: acetoacetate + coenzyme M + NADP(+) = 2-oxopropyl-coenzyme M + CO(2) + NADPH.	tmpzr1t_l9r_go_relaxed.owl	2-mercaptoethanesulfonate,acetoacetate:NADP+ oxidoreductase (decarboxylating)|2-KPCC activity|NADPH:2-(2-ketopropylthio)ethanesulfonate oxidoreductase/carboxylase activity|NADPH:2-ketopropyl-coenzyme M oxidoreductase/carboxylase activity				UM-BBD_reactionID:r0854|MetaCyc:1.8.1.5-RXN|EC:1.8.1.5|KEGG_REACTION:R05713|RHEA:16977									molecular_function											owl:Class	
GO:1902503	biolink:NamedThing	adenylyltransferase complex	A protein complex which is capable of adenylyltransferase activity.	tmpzr1t_l9r_go_relaxed.owl	ThiF-ThiS complex							bhm	2013-11-14T10:37:25Z					cellular_component											owl:Class	
GO:0061695	biolink:NamedThing	transferase complex, transferring phosphorus-containing groups	A transferase complex capable of catalysis of the transfer of a phosphorus-containing group from one compound (donor) to another (acceptor).	tmpzr1t_l9r_go_relaxed.owl								dph	2015-05-06T11:22:38Z					cellular_component											owl:Class	
GO:2000954	biolink:NamedThing	regulation of cyclodextrin metabolic process	Any process that modulates the frequency, rate or extent of cyclodextrin metabolic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of cyclodextrin metabolism							tt	2011-08-01T02:22:00Z					biological_process											owl:Class	
GO:0052599	biolink:NamedThing	methylputrescine oxidase activity	Catalysis of the reaction: N-methylputrescine + H2O + O2 = N-methylaminobutanal + NH3 + hydrogen peroxide + H+.	tmpzr1t_l9r_go_relaxed.owl	N-methylputrescine:oxygen oxidoreductase (deaminating) activity				MetaCyc:RXN-8244|KEGG_REACTION:R05334|EC:1.4.3.22									molecular_function											owl:Class	
GO:0042358	biolink:NamedThing	thiamine diphosphate catabolic process	The chemical reactions and pathways resulting in the breakdown of thiamine diphosphate, a derivative of thiamine (vitamin B1) which acts as a coenzyme in a range of processes including the Krebs cycle.	tmpzr1t_l9r_go_relaxed.owl	thiamine pyrophosphate catabolism|thiamin diphosphate degradation|thiamine pyrophosphate catabolic process|thiamin pyrophosphate catabolic process|thiamin diphosphate catabolic process|thiamine diphosphate catabolism|thiamin diphosphate breakdown|thiamin diphosphate catabolism|TPP catabolic process|TPP catabolism|thiamin pyrophosphate catabolism													biological_process											owl:Class	
GO:0009868	biolink:NamedThing	jasmonic acid and ethylene-dependent systemic resistance, jasmonic acid mediated signaling pathway	The series of molecular signals mediated by jasmonic acid involved in jasmonic acid/ethylene (ethene) dependent systemic resistance.	tmpzr1t_l9r_go_relaxed.owl	jasmonic acid/ethylene-dependent systemic resistance, jasmonic acid mediated signalling pathway|jasmonic acid mediated signaling pathway (jasmonic acid/ethylene-dependent systemic resistance)|jasmonic acid and ethene-dependent systemic resistance, jasmonic acid mediated signaling pathway|jasmonic acid mediated signaling pathway (jasmonic acid/ethene-dependent systemic resistance)|jasmonic acid/ethylene-dependent systemic resistance, jasmonic acid mediated signaling pathway|jasmonic acid/ethene-dependent systemic resistance, jasmonic acid mediated signalling pathway|jasmonic acid/ethene-dependent systemic resistance, jasmonic acid mediated signaling pathway													biological_process											owl:Class	
GO:0009867	biolink:NamedThing	jasmonic acid mediated signaling pathway	A series of molecular signals mediated by jasmonic acid.	tmpzr1t_l9r_go_relaxed.owl	jasmonic acid mediated signalling pathway|JA signaling|jasmonate signaling													biological_process											owl:Class	
GO:1903760	biolink:NamedThing	regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization	Any process that modulates the frequency, rate or extent of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization.	tmpzr1t_l9r_go_relaxed.owl	regulation of voltage-dependent potassium channel activity involved in ventricular cardiac muscle cell action potential|regulation of voltage-sensitive potassium channel involved in ventricular cardiac muscle cell action potential|regulation of voltage gated potassium channel activity involved in ventricular cardiac muscle cell action potential|regulation of voltage-gated potassium ion channel activity involved in ventricular cardiac muscle cell action potential							rl	2014-12-19T12:01:59Z					biological_process											owl:Class	
GO:1901016	biolink:NamedThing	regulation of potassium ion transmembrane transporter activity	Any process that modulates the frequency, rate or extent of potassium ion transmembrane transporter activity.	tmpzr1t_l9r_go_relaxed.owl	regulation of potassium transporter activity							rl	2012-06-15T01:13:49Z					biological_process											owl:Class	
GO:0047090	biolink:NamedThing	benzoyl-CoA 3-monooxygenase activity	Catalysis of the reaction: benzoyl-CoA + H(+) + NADPH + O(2) = 3-hydroxybenzoyl-CoA + H(2)O + NADP(+).	tmpzr1t_l9r_go_relaxed.owl	benzoyl-CoA 3-hydroxylase activity|benzoyl-CoA,NADPH:oxygen oxidoreductase (3-hydroxylating)				RHEA:23216|KEGG_REACTION:R02449|EC:1.14.13.58|MetaCyc:1.14.13.58-RXN									molecular_function											owl:Class	
GO:0106124	biolink:NamedThing	reservosome lumen	The volume enclosed by the membranes of a reservosome.	tmpzr1t_l9r_go_relaxed.owl								hjd	2018-05-03T17:54:46Z					cellular_component											owl:Class	
GO:1905299	biolink:NamedThing	negative regulation of intestinal epithelial cell development	Any process that stops, prevents or reduces the frequency, rate or extent of intestinal epithelial cell development.	tmpzr1t_l9r_go_relaxed.owl	down regulation of intestinal epithelial cell development|downregulation of intestinal epithelial cell development|down-regulation of intestinal epithelial cell development|inhibition of intestinal epithelial cell development							rph	2016-06-30T11:40:55Z					biological_process											owl:Class	
GO:0030857	biolink:NamedThing	negative regulation of epithelial cell differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of epithelial cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	inhibition of epithelial cell differentiation|down-regulation of epithelial cell differentiation|down regulation of epithelial cell differentiation|downregulation of epithelial cell differentiation													biological_process											owl:Class	
GO:1905514	biolink:NamedThing	positive regulation of short-term synaptic potentiation	Any process that activates or increases the frequency, rate or extent of short-term synaptic potentiation.	tmpzr1t_l9r_go_relaxed.owl	up regulation of synaptic facilitation|upregulation of synaptic facilitation|up-regulation of short-term synaptic potentiation|up-regulation of synaptic facilitation|upregulation of short-term synaptic potentiation|activation of short-term synaptic potentiation|up regulation of short-term synaptic potentiation|positive regulation of synaptic facilitation|activation of synaptic facilitation							hjd	2016-09-28T17:40:30Z					biological_process											owl:Class	
GO:0102089	biolink:NamedThing	dehydroscoulerine synthase activity	Catalysis of the reaction: (S)-scoulerine + O2 = dehydroscoulerine + hydrogen peroxide + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-10888									molecular_function											owl:Class	
GO:0046993	biolink:NamedThing	oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond, with oxygen as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which X-H and Y-H form X-Y and the acceptor is oxygen.	tmpzr1t_l9r_go_relaxed.owl					EC:1.21.3.-									molecular_function											owl:Class	
GO:0102938	biolink:NamedThing	orcinol O-methyltransferase activity	Catalysis of the reaction: orcinol + S-adenosyl-L-methionine  = H+ + 3-methoxy-5-hydroxytoluene + S-adenosyl-L-homocysteine.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-9017|EC:2.1.1.6									molecular_function											owl:Class	
GO:0032691	biolink:NamedThing	negative regulation of interleukin-1 beta production	Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-1 beta production.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of interleukin-1 beta biosynthetic process|down regulation of interleukin-1 beta production|negative regulation of interleukin-1 beta secretion|down-regulation of interleukin-1 beta production|negative regulation of IL-1 beta production|downregulation of interleukin-1 beta production|inhibition of interleukin-1 beta production											GO:0050724|GO:0050713		biological_process											owl:Class	
GO:0035453	biolink:NamedThing	extrinsic component of plastid inner membrane	The component of a plastid inner membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.	tmpzr1t_l9r_go_relaxed.owl	extrinsic to plastid inner membrane|peripheral to plastid inner membrane							bf	2010-04-16T10:21:14Z					cellular_component											owl:Class	
GO:0035452	biolink:NamedThing	extrinsic component of plastid membrane	The component of a plastid membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.	tmpzr1t_l9r_go_relaxed.owl	extrinsic to plastid membrane|peripheral to plastid membrane							bf	2010-04-16T10:19:33Z					cellular_component											owl:Class	
GO:0090233	biolink:NamedThing	negative regulation of spindle checkpoint	Any process that decreases the rate, frequency, or extent of the spindle checkpoint, a cell cycle checkpoint that delays the metaphase/anaphase transition until the spindle is correctly assembled and oriented, and chromosomes are attached to the spindle.	tmpzr1t_l9r_go_relaxed.owl	spindle checkpoint silencing					Note that this term should not be used for direct manual annotation as it should always be possible to specify the type of checkpoint (i.e mitotic spindle or DNA damage etc).		tb	2010-01-20T10:29:43Z					biological_process											owl:Class	
GO:0090231	biolink:NamedThing	regulation of spindle checkpoint	Any process that modulates the rate, frequency, or extent of the spindle checkpoint, a cell cycle checkpoint that delays the metaphase/anaphase transition until the spindle is correctly assembled and oriented, and chromosomes are attached to the spindle.	tmpzr1t_l9r_go_relaxed.owl						Note that this term should not be used for direct manual annotation as it should always be possible to specify the type of checkpoint (i.e mitotic spindle or DNA damage etc).		tb	2010-01-20T10:29:43Z					biological_process											owl:Class	
GO:1902326	biolink:NamedThing	positive regulation of chlorophyll biosynthetic process	Any process that activates or increases the frequency, rate or extent of chlorophyll biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	upregulation of chlorophyll synthesis|upregulation of chlorophyll formation|activation of chlorophyll biosynthetic process|positive regulation of chlorophyll formation|activation of chlorophyll formation|upregulation of chlorophyll biosynthetic process|up regulation of chlorophyll synthesis|up regulation of chlorophyll biosynthesis|up regulation of chlorophyll formation|activation of chlorophyll synthesis|up regulation of chlorophyll biosynthetic process|up regulation of chlorophyll anabolism|activation of chlorophyll biosynthesis|activation of chlorophyll anabolism|up-regulation of chlorophyll formation|up-regulation of chlorophyll biosynthetic process|upregulation of chlorophyll anabolism|positive regulation of chlorophyll biosynthesis|upregulation of chlorophyll biosynthesis|up-regulation of chlorophyll synthesis|up-regulation of chlorophyll anabolism|positive regulation of chlorophyll anabolism|up-regulation of chlorophyll biosynthesis|positive regulation of chlorophyll synthesis							tb	2013-07-24T22:47:37Z					biological_process											owl:Class	
GO:0010380	biolink:NamedThing	regulation of chlorophyll biosynthetic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of chlorophyll, any compound of magnesium complexed in a porphyrin (tetrapyrrole) ring and which functions as a photosynthetic pigment, from less complex precursors.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1902854	biolink:NamedThing	positive regulation of nuclear migration during mitotic telophase	Any process that activates or increases the frequency, rate or extent of nuclear migration during mitotic telophase.	tmpzr1t_l9r_go_relaxed.owl	activation of nuclear migration during mitotic telophase|upregulation of nuclear migration during mitotic telophase|up regulation of nuclear migration during mitotic telophase|up-regulation of nuclear migration during mitotic telophase							vw	2014-04-02T15:36:06Z					biological_process											owl:Class	
GO:1902852	biolink:NamedThing	regulation of nuclear migration during mitotic telophase	Any process that modulates the frequency, rate or extent of nuclear migration during mitotic telophase.	tmpzr1t_l9r_go_relaxed.owl								vw	2014-04-02T15:35:34Z					biological_process											owl:Class	
GO:0070904	biolink:NamedThing	transepithelial L-ascorbic acid transport	The directed movement of L-ascorbic acid from one side of an epithelium to the other.	tmpzr1t_l9r_go_relaxed.owl	transepithelial vitamin C transport|transepithelial L-ascorbate transport							mah	2009-09-03T02:21:25Z					biological_process											owl:Class	
GO:0008643	biolink:NamedThing	carbohydrate transport	The directed movement of carbohydrate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Carbohydrates are a group of organic compounds based of the general formula Cx(H2O)y.	tmpzr1t_l9r_go_relaxed.owl	sugar transport											GO:0006861|GO:0008644		biological_process											owl:Class	
GO:0051919	biolink:NamedThing	positive regulation of fibrinolysis	Any process that activates, maintains or increases the frequency, rate or extent of fibrinolysis, an ongoing process that solubilizes fibrin, resulting in the removal of small blood clots.	tmpzr1t_l9r_go_relaxed.owl	upregulation of fibrinolysis|up regulation of fibrinolysis|stimulation of fibrinolysis|up-regulation of fibrinolysis|activation of fibrinolysis													biological_process											owl:Class	
GO:2000288	biolink:NamedThing	positive regulation of myoblast proliferation	Any process that activates or increases the frequency, rate or extent of myoblast proliferation.	tmpzr1t_l9r_go_relaxed.owl								rl	2010-12-16T05:20:52Z					biological_process											owl:Class	
GO:2000291	biolink:NamedThing	regulation of myoblast proliferation	Any process that modulates the frequency, rate or extent of myoblast proliferation.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-12-20T10:34:26Z					biological_process											owl:Class	
GO:0102337	biolink:NamedThing	3-oxo-cerotoyl-CoA synthase activity	Catalysis of the reaction: tetracosanoyl-CoA(4-) + malonyl-CoA(5-) + H+ <=> 3-oxohexacosanoyl-CoA + carbon dioxide + coenzyme A.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-13296|RHEA:36515									molecular_function											owl:Class	
GO:0048052	biolink:NamedThing	R1/R6 cell differentiation	The process in which relatively unspecialized cells acquire the specialized features of R1 and R6 photoreceptors. An example of this process is found in Drosophila melanogaster.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0001751	biolink:NamedThing	compound eye photoreceptor cell differentiation	The process in which a relatively unspecialized cell acquires the specialized features of an eye photoreceptor cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1901177	biolink:NamedThing	lycopene biosynthetic process	The chemical reactions and pathways resulting in the formation of lycopene.	tmpzr1t_l9r_go_relaxed.owl	lycopene anabolism|lycopene formation|lycopene biosynthesis|lycopene synthesis							yaf	2012-07-19T09:48:49Z					biological_process											owl:Class	
GO:1901175	biolink:NamedThing	lycopene metabolic process	The chemical reactions and pathways involving lycopene.	tmpzr1t_l9r_go_relaxed.owl	lycopene metabolism							yaf	2012-07-19T09:48:20Z					biological_process											owl:Class	
GO:0018839	biolink:NamedThing	cis-4-[2-(3-hydroxy)-thionaphthenyl]-2-oxo-3-butenoate isomerase activity	Catalysis of the reaction: cis-4-(2-(3-hydroxy)-thionaphthenyl)-2-oxo-3-butenoate = trans-4-(2-(3-hydroxy)-thionaphthenyl)-2-oxo-3-butenoate.	tmpzr1t_l9r_go_relaxed.owl					EC:5.2.1.-|UM-BBD_reactionID:r0163									molecular_function											owl:Class	
GO:0106298	biolink:NamedThing	13-series resolvin biosynthetic process	The chemical reactions and pathways resulting in the formation of resolvin family 13-series, hydroxy fatty acids derived from docosapentaenoic acid.	tmpzr1t_l9r_go_relaxed.owl								hjd	2020-08-25T13:50:53Z					biological_process											owl:Class	
GO:0106295	biolink:NamedThing	resolvin biosynthetic process	The chemical reactions and pathways resulting in the formation of resolvins, di- or trihydroxy fatty acids derived from omega-3 polyunsaturated fatty acids, specifically icosapentaenoic acid, docosahexaenoic acid and docosapentaenoic acid.	tmpzr1t_l9r_go_relaxed.owl						Resolvin biosynthesis is a combination of oxidation, reduction and hydrolysis reactions involving lipoxygenases and cyclooxygenases.		hjd	2020-08-25T13:46:15Z					biological_process											owl:Class	
GO:0042203	biolink:NamedThing	toluene catabolic process	The chemical reactions and pathways resulting in the breakdown of toluene, a volatile monoaromatic hydrocarbon found in crude petroleum and petroleum products.	tmpzr1t_l9r_go_relaxed.owl	toluene degradation|toluene catabolism|toluene breakdown													biological_process											owl:Class	
GO:0120253	biolink:NamedThing	hydrocarbon catabolic process	The chemical reactions and pathways resulting in the breakdown of a hydrocarbon, a compound consisting of carbon and hydrogen only.	tmpzr1t_l9r_go_relaxed.owl	hydrocarbon catabolism|hydrocarbon degradation|hydrocarbon breakdown	https://github.com/geneontology/go-ontology/issues/19842						krc	2020-09-02T20:58:57Z					biological_process											owl:Class	
GO:0047291	biolink:NamedThing	lactosylceramide alpha-2,3-sialyltransferase activity	Catalysis of the reaction: cytolipin-H + CMP-N-acetylneuraminate = alpha-N-acetylneuraminyl-2,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide + CMP. Alpha-N-acetylneuraminyl-2,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide is also known as GM3.	tmpzr1t_l9r_go_relaxed.owl	CMP-N-acetylneuraminate:lactosylceramide alpha-2,3-N-acetylneuraminyltransferase activity|cytidine monophosphoacetylneuraminate-lactosylceramide alpha2,3- sialyltransferase activity|cytidine monophosphoacetylneuraminate-lactosylceramide sialyltransferase|GM3 synthase activity|ganglioside GM3 synthetase activity|CMP-acetylneuraminate-lactosylceramide-sialyltransferase|GM3 synthetase activity|ganglioside GM3 synthase activity|SAT 1|CMP-sialic acid:lactosylceramide-sialyltransferase activity|CMP-acetylneuraminic acid:lactosylceramide sialyltransferase activity				MetaCyc:2.4.99.9-RXN|EC:2.4.99.9|RHEA:18417									molecular_function											owl:Class	
GO:0008373	biolink:NamedThing	sialyltransferase activity	Catalysis of the transfer of sialic acid to an acceptor molecule, typically the terminal portions of the sialylated glycolipids (gangliosides) or to the N- or O-linked sugar chains of glycoproteins.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-9694718|Reactome:R-HSA-981814|Reactome:R-HSA-9697018|Reactome:R-HSA-9683769									molecular_function											owl:Class	
GO:0045003	biolink:NamedThing	double-strand break repair via synthesis-dependent strand annealing	SDSA is a major mechanism of double-strand break repair in mitosis which allows for the error-free repair of a double-strand break without the exchange of adjacent sequences. The broken DNA searches for and base pairs with a homologous region in an intact chromosome. DNA synthesis initiates from the 3' end of the invading DNA strand, using the intact chromosome as the template. Newly synthesized DNA is then displaced from the template and anneal with its complement on the other side of the double-strand break.	tmpzr1t_l9r_go_relaxed.owl	mitotic gene conversion|SDSA													biological_process											owl:Class	
GO:0000724	biolink:NamedThing	double-strand break repair via homologous recombination	The error-free repair of a double-strand break in DNA in which the broken DNA molecule is repaired using homologous sequences. A strand in the broken DNA searches for a homologous region in an intact chromosome to serve as the template for DNA synthesis. The restoration of two intact DNA molecules results in the exchange, reciprocal or nonreciprocal, of genetic material between the intact DNA molecule and the broken DNA molecule.	tmpzr1t_l9r_go_relaxed.owl	Rhp51-dependent recombinational repair|HDR|homology-directed repair|homologous recombinational repair|HRR|Rad51-dependent recombinational repair											GO:0016924		biological_process											owl:Class	
GO:0140125	biolink:NamedThing	thiamine import across plasma membrane	The directed movement of thiamine from outside of a cell, across the plasma membrane and into the cytosol.	tmpzr1t_l9r_go_relaxed.owl								pg	2017-10-25T11:09:23Z					biological_process											owl:Class	
GO:0098739	biolink:NamedThing	import across plasma membrane	The directed movement of some substance from outside of a cell, across the plasma membrane and into the cytosol.	tmpzr1t_l9r_go_relaxed.owl	uptake													biological_process											owl:Class	
GO:0046066	biolink:NamedThing	dGDP metabolic process	The chemical reactions and pathways involving dGDP, deoxyguanosine diphosphate, (2'-deoxyguanosine 5'-diphosphate).	tmpzr1t_l9r_go_relaxed.owl	dGDP metabolism													biological_process											owl:Class	
GO:0009182	biolink:NamedThing	purine deoxyribonucleoside diphosphate metabolic process	The chemical reactions and pathways involving purine deoxyribonucleoside diphosphate, a compound consisting of a purine base linked to a deoxyribose sugar esterified with diphosphate on the sugar.	tmpzr1t_l9r_go_relaxed.owl	purine deoxyribonucleoside diphosphate metabolism													biological_process											owl:Class	
GO:0018887	biolink:NamedThing	4-carboxy-4'-sulfoazobenzene metabolic process	The chemical reactions and pathways involving 4-carboxy-4'-sulfoazobenzene, a sulfonated azo compound synthesized by nitro-amine condensation from sulfanilic acid and 4-nitrobenzoic acid.	tmpzr1t_l9r_go_relaxed.owl	4-carboxy-4'-sulphoazobenzene metabolism|4-carboxy-4'-sulphoazobenzene metabolic process|4-carboxy-4'-sulfoazobenzene metabolism				UM-BBD_pathwayID:csab									biological_process											owl:Class	
GO:0006807	biolink:NamedThing	nitrogen compound metabolic process	The chemical reactions and pathways involving organic or inorganic compounds that contain nitrogen.	tmpzr1t_l9r_go_relaxed.owl	nitrogen compound metabolism													biological_process											owl:Class	
GO:0004602	biolink:NamedThing	glutathione peroxidase activity	Catalysis of the reaction: 2 glutathione + hydrogen peroxide = oxidized glutathione + 2 H2O.	tmpzr1t_l9r_go_relaxed.owl	reduced glutathione peroxidase activity|selenium-glutathione peroxidase activity|glutathione:hydrogen-peroxide oxidoreductase activity|GSH peroxidase activity|non-selenium glutathione peroxidase activity				MetaCyc:GLUTATHIONE-PEROXIDASE-RXN|Reactome:R-HSA-71676|Reactome:R-HSA-2161999|EC:1.11.1.9|Reactome:R-HSA-2161946|Reactome:R-HSA-3343700|Reactome:R-HSA-3323013|Reactome:R-HSA-2161959|RHEA:16833|Reactome:R-HSA-6799695|Reactome:R-HSA-3341277|Reactome:R-HSA-3341397|Reactome:R-HSA-2161791							GO:0016224		molecular_function											owl:Class	
GO:0004601	biolink:NamedThing	peroxidase activity	Catalysis of the reaction: donor + hydrogen peroxide = oxidized donor + 2 H2O.	tmpzr1t_l9r_go_relaxed.owl	donor:hydrogen-peroxide oxidoreductase activity|pyrocatechol peroxidase|verdoperoxidase|oxyperoxidase activity|lactoperoxidase activity|bacterial catalase-peroxidase activity|MPO|protoheme peroxidase|heme peroxidase|extensin peroxidase|peroxidase reaction|scopoletin peroxidase|eosinophil peroxidase activity|secretory plant peroxidase activity|thiocyanate peroxidase|japanese radish peroxidase|guaiacol peroxidase|myeloperoxidase activity|horseradish peroxidase (HRP)				Reactome:R-HSA-209840|Reactome:R-HSA-140359|Reactome:R-HSA-1222346|Reactome:R-HSA-3341296|Reactome:R-HSA-6789031|Reactome:R-HSA-2309773|Reactome:R-HSA-209815|Reactome:R-HSA-209973|Reactome:R-HSA-350901|Reactome:R-HSA-8855490|EC:1.11.1.-|Reactome:R-HSA-2559639|Reactome:R-HSA-6789126|KEGG_REACTION:R03532|Reactome:R-HSA-5631885|Reactome:R-HSA-209925|Reactome:R-HSA-8933635|MetaCyc:PEROXID-RXN							GO:0016693|GO:0016686|GO:0016685|GO:0016687		molecular_function											owl:Class	
GO:0051152	biolink:NamedThing	positive regulation of smooth muscle cell differentiation	Any process that activates or increases the frequency, rate or extent of smooth muscle cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	stimulation of smooth muscle cell differentiation|up-regulation of smooth muscle cell differentiation|activation of smooth muscle cell differentiation|up regulation of smooth muscle cell differentiation|upregulation of smooth muscle cell differentiation													biological_process											owl:Class	
GO:0098516	biolink:NamedThing	detection of high humidity	The series of events in which high humidity is detected and converted into a molecular signal.	tmpzr1t_l9r_go_relaxed.owl								dos	2013-09-25T14:26:47Z					biological_process											owl:Class	
GO:0098513	biolink:NamedThing	detection of humidity	The series of events in which a humidity stimulus is received and converted into a molecular signal.	tmpzr1t_l9r_go_relaxed.owl								dos	2013-09-25T14:11:13Z					biological_process											owl:Class	
GO:1900603	biolink:NamedThing	tensidol A metabolic process	The chemical reactions and pathways involving tensidol A.	tmpzr1t_l9r_go_relaxed.owl	tensidol A metabolism							di	2012-05-15T06:57:47Z					biological_process											owl:Class	
GO:1904322	biolink:NamedThing	cellular response to forskolin	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a forskolin stimulus.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-06-10T19:01:33Z					biological_process											owl:Class	
GO:1901655	biolink:NamedThing	cellular response to ketone	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ketone stimulus.	tmpzr1t_l9r_go_relaxed.owl								pr	2012-11-20T10:55:51Z					biological_process											owl:Class	
GO:0090664	biolink:NamedThing	response to high population density	Any process that results in a change in state or activity of a cell or a multicellular organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a higher than normal number of multicellular organisms living per unit area.	tmpzr1t_l9r_go_relaxed.owl	response to crowding							tb	2015-10-21T16:00:30Z					biological_process											owl:Class	
GO:0039516	biolink:NamedThing	modulation by virus of host catalytic activity	The process in which a virus effects a change in host enzyme activity.	tmpzr1t_l9r_go_relaxed.owl	modulation of catalytic activity of host by virus|regulation by virus of host catalytic activity|regulation of host catalytic activity by virus							bf	2011-06-16T02:59:35Z					biological_process											owl:Class	
GO:0050371	biolink:NamedThing	tyrosine phenol-lyase activity	Catalysis of the reaction: L-tyrosine + H(2)O = NH(4)(+) + phenol + pyruvate.	tmpzr1t_l9r_go_relaxed.owl	beta-tyrosinase activity|L-tyrosine phenol-lyase (deaminating; pyruvate-forming)|L-tyrosine phenol-lyase (deaminating)				RHEA:21704|KEGG_REACTION:R00728|MetaCyc:TYROSINE-PHENOL-LYASE-RXN|EC:4.1.99.2									molecular_function											owl:Class	
GO:0018761	biolink:NamedThing	bromoxynil nitrilase activity	Catalysis of the reaction: 3,5-dibromo-4-hydroxybenzonitrile + 2 H(2)O = 3,5-dibromo-4-hydroxybenzoate + NH(4)(+). Involved in the bacterial degradation of the herbicide bromoxynil.	tmpzr1t_l9r_go_relaxed.owl	bromoxynil-specific nitrilase activity|3,5-dibromo-4-hydroxybenzonitrile aminohydrolase activity				RHEA:22100|KEGG_REACTION:R04349|MetaCyc:3.5.5.6-RXN|EC:3.5.5.6|UM-BBD_enzymeID:e0357									molecular_function											owl:Class	
GO:0000257	biolink:NamedThing	nitrilase activity	Catalysis of the reaction: a nitrile + H2O = a carboxylate + NH3. Acts on a wide range of aromatic nitriles including (indole-3-yl)-acetonitrile and some aliphatic nitriles, and on the corresponding acid amides.	tmpzr1t_l9r_go_relaxed.owl	benzonitrilase activity|nitrile aminohydrolase activity|acetonitrilase activity				MetaCyc:3.5.5.1-RXN|KEGG_REACTION:R00540|UM-BBD_enzymeID:e0283|EC:3.5.5.1|RHEA:21724									molecular_function											owl:Class	
GO:1905162	biolink:NamedThing	regulation of phagosome maturation	Any process that modulates the frequency, rate or extent of phagosome maturation.	tmpzr1t_l9r_go_relaxed.owl								bf	2016-04-25T16:28:03Z					biological_process											owl:Class	
GO:1905919	biolink:NamedThing	negative regulation of CoA-transferase activity	Any process that stops, prevents or reduces the frequency, rate or extent of CoA-transferase activity.	tmpzr1t_l9r_go_relaxed.owl	down regulation of CoA-transferase activity|downregulation of CoA-transferase activity|inhibition of CoA-transferase activity|down-regulation of CoA-transferase activity							bc	2017-02-08T13:00:56Z					biological_process											owl:Class	
GO:0071137	biolink:NamedThing	alphaV-beta3 integrin-CD98 complex	A protein complex that consists of an alphaV-beta3 integrin complex bound to the cell surface antigen CD98.	tmpzr1t_l9r_go_relaxed.owl	ITGAV-ITGB3-SLC3A2 complex							mah	2009-11-13T02:29:59Z					cellular_component											owl:Class	
GO:1903762	biolink:NamedThing	positive regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization	Any process that activates or increases the frequency, rate or extent of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization.	tmpzr1t_l9r_go_relaxed.owl	up regulation of voltage-dependent potassium channel activity involved in ventricular cardiac muscle cell action potential|positive regulation of voltage gated potassium channel activity involved in ventricular cardiac muscle cell action potential|upregulation of voltage-sensitive potassium channel involved in ventricular cardiac muscle cell action potential|positive regulation of voltage-dependent potassium channel activity involved in ventricular cardiac muscle cell action potential|up-regulation of voltage-dependent potassium channel activity involved in ventricular cardiac muscle cell action potential|positive regulation of voltage-sensitive potassium channel involved in ventricular cardiac muscle cell action potential|upregulation of voltage-gated potassium ion channel activity involved in ventricular cardiac muscle cell action potential|up regulation of voltage gated potassium channel activity involved in ventricular cardiac muscle cell action potential|activation of voltage-gated potassium ion channel activity involved in ventricular cardiac muscle cell action potential|activation of voltage gated potassium channel activity involved in ventricular cardiac muscle cell action potential|up regulation of voltage-gated potassium ion channel activity involved in ventricular cardiac muscle cell action potential|activation of voltage-sensitive potassium channel involved in ventricular cardiac muscle cell action potential|positive regulation of voltage-gated potassium ion channel activity involved in ventricular cardiac muscle cell action potential|up regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization|activation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization|upregulation of voltage gated potassium channel activity involved in ventricular cardiac muscle cell action potential|upregulation of voltage-dependent potassium channel activity involved in ventricular cardiac muscle cell action potential|up-regulation of voltage gated potassium channel activity involved in ventricular cardiac muscle cell action potential|up-regulation of voltage-gated potassium ion channel activity involved in ventricular cardiac muscle cell action potential|up regulation of voltage-sensitive potassium channel involved in ventricular cardiac muscle cell action potential|up-regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization|activation of voltage-dependent potassium channel activity involved in ventricular cardiac muscle cell action potential|upregulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization|up-regulation of voltage-sensitive potassium channel involved in ventricular cardiac muscle cell action potential							rl	2014-12-19T12:02:18Z					biological_process											owl:Class	
GO:1905026	biolink:NamedThing	positive regulation of membrane repolarization during ventricular cardiac muscle cell action potential	Any process that activates or increases the frequency, rate or extent of membrane repolarization during ventricular cardiac muscle cell action potential.	tmpzr1t_l9r_go_relaxed.owl	up regulation of electrocardiogram T wave|activation of ventricular repolarization|upregulation of electrocardiogram T wave|up regulation of ventricular repolarization|up-regulation of regulation of ventricular cardiac muscle repolarization|up regulation of regulation of ventricular cardiac muscle repolarization|up-regulation of ventricular repolarization|upregulation of membrane repolarization during ventricular cardiac muscle cell action potential|up regulation of membrane repolarization during ventricular cardiac muscle cell action potential|positive regulation of regulation of ventricular cardiac muscle repolarization|activation of membrane repolarization during ventricular cardiac muscle cell action potential|up-regulation of electrocardiogram T wave|activation of electrocardiogram T wave|up-regulation of membrane repolarization during ventricular cardiac muscle cell action potential|positive regulation of electrocardiogram T wave|positive regulation of ventricular repolarization|upregulation of ventricular repolarization|activation of regulation of ventricular cardiac muscle repolarization|upregulation of regulation of ventricular cardiac muscle repolarization							rph	2016-03-04T11:19:21Z					biological_process											owl:Class	
GO:0046951	biolink:NamedThing	ketone body biosynthetic process	The chemical reactions and pathways resulting in the formation of ketone bodies, any one of the three substances: acetoacetate, D-3-hydroxybutyrate (beta-hydroxybutyrate) or acetone. Biosynthesis involves the formation of hydroxymethylglutaryl-CoA, which is cleaved to acetate and acetyl-CoA.	tmpzr1t_l9r_go_relaxed.owl	ketone body formation|ketone body anabolism|ketone body biosynthesis|ketone body synthesis													biological_process											owl:Class	
GO:1902224	biolink:NamedThing	ketone body metabolic process	The chemical reactions and pathways involving ketone body.	tmpzr1t_l9r_go_relaxed.owl	ketone body metabolism							pr	2013-06-13T10:37:54Z					biological_process											owl:Class	
GO:0050926	biolink:NamedThing	regulation of positive chemotaxis	Any process that modulates the frequency, rate or extent of the directed movement of a motile cell or organism towards a higher concentration in a concentration gradient of a specific chemical.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0010940	biolink:NamedThing	positive regulation of necrotic cell death	Any process that increases the rate, frequency or extent of necrotic cell death. Necrotic cell death is a cell death process that is morphologically characterized by a gain in cell volume (oncosis), swelling of organelles, plasma membrane rupture and subsequent loss of intracellular contents.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0010942	biolink:NamedThing	positive regulation of cell death	Any process that increases the rate or frequency of cell death. Cell death is the specific activation or halting of processes within a cell so that its vital functions markedly cease, rather than simply deteriorating gradually over time, which culminates in cell death.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0140426	biolink:NamedThing	PAMP-triggered immunity signalling pathway	Any series of molecular signals generated as a consequence of a pattern recognition receptor (PRR) binding to one of its physiological ligands to activate a plant innate immune response. PAMP-triggered immunity PRRs bind pathogen-associated molecular pattern (PAMPs), structures conserved among microbial species.	tmpzr1t_l9r_go_relaxed.owl	pathogen-associated molecular pattern signalling|PTI signalling|MAMP-triggered immunity signalling	https://github.com/geneontology/go-ontology/issues/18588						pg	2020-02-11T11:08:57Z					biological_process											owl:Class	
GO:0002758	biolink:NamedThing	innate immune response-activating signal transduction	A series of molecular signals generated as a consequence of a pathogen or microbial effector binding to a plant 'resistance-gene' receptor to activate a plant immune response, usually plant-type hypersensitive response.	tmpzr1t_l9r_go_relaxed.owl	defense response signaling pathway, resistance gene-independent|defence response signaling pathway, resistance gene-independent|defence response signalling pathway, resistance gene-independent|defence response signalling pathway, resistance gene-dependent|effector triggered immunity|defense response signalling pathway, resistance gene-dependent|effector-triggered immunity|defense response signaling pathway, resistance gene-dependent|effector-triggered immune signaling|defence response signaling pathway, resistance gene-dependent	https://github.com/geneontology/go-ontology/issues/18587|https://github.com/geneontology/go-ontology/issues/18586|https://github.com/geneontology/go-ontology/issues/18733|https://github.com/geneontology/go-ontology/issues/19850										GO:0010204|GO:0009870		biological_process											owl:Class	
GO:0033869	biolink:NamedThing	nucleoside bisphosphate catabolic process	The chemical reactions and pathways resulting in the breakdown of a nucleoside bisphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar.	tmpzr1t_l9r_go_relaxed.owl	nucleoside bisphosphate breakdown|nucleoside bisphosphate degradation|nucleoside bisphosphate catabolism													biological_process											owl:Class	
GO:1901292	biolink:NamedThing	nucleoside phosphate catabolic process	The chemical reactions and pathways resulting in the breakdown of a nucleoside phosphate.	tmpzr1t_l9r_go_relaxed.owl	nucleoside phosphate breakdown|nucleoside phosphate catabolism|nucleoside phosphate degradation							bf	2012-08-20T12:33:25Z					biological_process											owl:Class	
GO:0051550	biolink:NamedThing	aurone metabolic process	The chemical reactions and pathways involving aurones, a series of plant flavonoids that provide a yellow colour to flowers. They have the basic skeletal structure of two benzene rings joined by a linear C3 chain (C6-C3-C6). Aurones exist mostly as 6-O-glucosides.	tmpzr1t_l9r_go_relaxed.owl	aurone metabolism|benzalcoumaran-3-one metabolic process|benzalcoumaran-3-one metabolism													biological_process											owl:Class	
GO:1902290	biolink:NamedThing	positive regulation of defense response to oomycetes	Any process that activates or increases the frequency, rate or extent of defense response to oomycetes.	tmpzr1t_l9r_go_relaxed.owl	activation of defense response to oomycetes|up regulation of defense response to oomycetes|up-regulation of defense response to oomycetes|upregulation of defense response to oomycetes							ms	2013-07-09T13:45:43Z					biological_process											owl:Class	
GO:0031349	biolink:NamedThing	positive regulation of defense response	Any process that activates or increases the frequency, rate or extent of a defense response.	tmpzr1t_l9r_go_relaxed.owl	stimulation of defense response|up regulation of defense response|up-regulation of defense response|upregulation of defense response|activation of defense response													biological_process											owl:Class	
GO:2000417	biolink:NamedThing	negative regulation of eosinophil migration	Any process that stops, prevents or reduces the frequency, rate or extent of eosinophil migration.	tmpzr1t_l9r_go_relaxed.owl								mah	2011-02-23T01:43:52Z					biological_process											owl:Class	
GO:1900790	biolink:NamedThing	pseurotin A biosynthetic process	The chemical reactions and pathways resulting in the formation of pseurotin A.	tmpzr1t_l9r_go_relaxed.owl	pseurotin A anabolism|Pseurotin synthesis|pseurotin A formation|pseurotin A synthesis|Pseurotin anabolism|Pseurotin formation|Pseurotin biosynthesis|Pseurotin biosynthetic process|pseurotin A biosynthesis							di	2012-06-04T09:37:49Z					biological_process											owl:Class	
GO:1905187	biolink:NamedThing	negative regulation of metaphase/anaphase transition of meiosis I	Any process that stops, prevents or reduces the frequency, rate or extent of metaphase/anaphase transition of meiosis I.	tmpzr1t_l9r_go_relaxed.owl								vw	2016-05-10T16:32:11Z					biological_process											owl:Class	
GO:1905186	biolink:NamedThing	regulation of metaphase/anaphase transition of meiosis I	Any process that modulates the frequency, rate or extent of metaphase/anaphase transition of meiosis I.	tmpzr1t_l9r_go_relaxed.owl	regulation of meiosis I metaphase/anaphase transition|regulation of first meiotic metaphase/anaphase transition							vw	2016-05-10T16:32:03Z					biological_process											owl:Class	
GO:1903614	biolink:NamedThing	negative regulation of protein tyrosine phosphatase activity	Any process that stops, prevents or reduces the frequency, rate or extent of protein tyrosine phosphatase activity.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of PTP-phosphatase activity|inhibition of protein-tyrosine-phosphatase activity|down regulation of phosphotyrosine phosphatase activity|negative regulation of phosphoprotein phosphatase (phosphotyrosine) activity|inhibition of PTP-phosphatase activity|inhibition of tyrosine O-phosphate phosphatase activity|negative regulation of [phosphotyrosine]protein phosphatase activity|down-regulation of phosphoprotein phosphatase (phosphotyrosine) activity|inhibition of protein tyrosine phosphatase activity|negative regulation of phosphotyrosine phosphatase activity|inhibition of [phosphotyrosine]protein phosphatase activity|down-regulation of phosphotyrosine protein phosphatase activity|down regulation of protein-tyrosine-phosphate phosphohydrolase activity|down-regulation of phosphotyrosylprotein phosphatase activity|negative regulation of protein phosphotyrosine phosphatase activity|inhibition of phosphotyrosine phosphatase activity|negative regulation of tyrosine O-phosphate phosphatase activity|negative regulation of phosphotyrosine protein phosphatase activity|down regulation of protein tyrosine phosphatase activity|downregulation of phosphotyrosylprotein phosphatase activity|down-regulation of PTP-phosphatase activity|down regulation of protein phosphotyrosine phosphatase activity|downregulation of phosphoprotein phosphatase (phosphotyrosine) activity|down regulation of phosphotyrosylprotein phosphatase activity|down regulation of PPT-phosphatase activity|downregulation of protein phosphotyrosine phosphatase activity|down regulation of phosphotyrosine protein phosphatase activity|negative regulation of protein-tyrosine-phosphate phosphohydrolase activity|down-regulation of protein phosphotyrosine phosphatase activity|down regulation of PTP-phosphatase activity|downregulation of phosphotyrosine phosphatase activity|inhibition of protein phosphotyrosine phosphatase activity|inhibition of tyrosylprotein phosphatase activity|inhibition of phosphotyrosine protein phosphatase activity|down regulation of phosphoprotein phosphatase (phosphotyrosine) activity|downregulation of protein tyrosine phosphatase activity|downregulation of tyrosine O-phosphate phosphatase activity|inhibition of PPT-phosphatase activity|negative regulation of phosphotyrosylprotein phosphatase activity|negative regulation of PTPase activity|down-regulation of phosphotyrosine phosphatase activity|inhibition of PTPase activity|downregulation of [phosphotyrosine]protein phosphatase activity|downregulation of protein-tyrosine-phosphatase activity|inhibition of phosphotyrosine histone phosphatase activity|down-regulation of [phosphotyrosine]protein phosphatase activity|down regulation of tyrosylprotein phosphatase activity|down regulation of phosphotyrosine histone phosphatase activity|down-regulation of tyrosine O-phosphate phosphatase activity|down regulation of tyrosine O-phosphate phosphatase activity|negative regulation of tyrosylprotein phosphatase activity|inhibition of protein-tyrosine-phosphate phosphohydrolase activity|down-regulation of protein-tyrosine-phosphatase activity|down regulation of [phosphotyrosine]protein phosphatase activity|downregulation of PPT-phosphatase activity|down-regulation of tyrosylprotein phosphatase activity|down-regulation of PTPase activity|down regulation of protein-tyrosine-phosphatase activity|downregulation of PTPase activity|downregulation of tyrosylprotein phosphatase activity|down-regulation of PPT-phosphatase activity|inhibition of phosphoprotein phosphatase (phosphotyrosine) activity|downregulation of PTP-phosphatase activity|down-regulation of phosphotyrosine histone phosphatase activity|down-regulation of protein tyrosine phosphatase activity|down-regulation of protein-tyrosine-phosphate phosphohydrolase activity|negative regulation of phosphotyrosine histone phosphatase activity|negative regulation of PPT-phosphatase activity|negative regulation of protein-tyrosine-phosphatase activity|downregulation of protein-tyrosine-phosphate phosphohydrolase activity|inhibition of phosphotyrosylprotein phosphatase activity|downregulation of phosphotyrosine protein phosphatase activity|downregulation of phosphotyrosine histone phosphatase activity|down regulation of PTPase activity							sl	2014-11-18T01:11:46Z					biological_process											owl:Class	
GO:0032515	biolink:NamedThing	negative regulation of phosphoprotein phosphatase activity	Any process that stops or reduces the activity of a phosphoprotein phosphatase.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of protein phosphatase type 2A activity|down-regulation of protein phosphatase type 2A activity|downregulation of phosphoprotein phosphatase activity|down regulation of protein phosphatase 2 activity|downregulation of protein phosphatase 2 activity|regulation of protein phosphatase 3 activity|down-regulation of phosphoprotein phosphatase activity|downregulation of protein phosphatase 3 activity|downregulation of protein phosphatase type 2B activity|negative regulation of protein phosphatase type 2B activity|down regulation of phosphoprotein phosphatase activity|downregulation of protein phosphatase type 2A activity|down regulation of protein phosphatase type 2B activity|inhibition of phosphoprotein phosphatase activity|downregulation of calcineurin activity|inhibition of protein phosphatase type 2B activity|down-regulation of protein phosphatase type 2B activity|down regulation of calcineurin activity|inhibition of protein phosphatase 3 activity|negative regulation of calcineurin activity|inhibition of protein phosphatase type 2A activity|down regulation of protein phosphatase type 2A activity|inhibition of calcineurin activity|inhibition of protein phosphatase 2 activity|down regulation of protein phosphatase 3 activity|negative regulation of protein phosphatase 2 activity											GO:0032513|GO:0034048		biological_process											owl:Class	
GO:2000694	biolink:NamedThing	regulation of phragmoplast microtubule organization	Any process that modulates the frequency, rate or extent of phragmoplast microtubule organization.	tmpzr1t_l9r_go_relaxed.owl	regulation of phragmoplast microtubule cytoskeleton organization|regulation of phragmoplast microtubule organisation							tb	2011-05-13T09:32:27Z					biological_process											owl:Class	
GO:0016751	biolink:NamedThing	S-succinyltransferase activity	Catalysis of the transfer of a succinyl group to a sulfur atom on the acceptor molecule.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0016417	biolink:NamedThing	S-acyltransferase activity	Catalysis of the transfer of an acyl group to a sulfur atom on the acceptor molecule.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0033219	biolink:NamedThing	urea binding	Binding to urea, a water-soluble carboxamide with the structure H2N-CO-NH2.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0033218	biolink:NamedThing	amide binding	Binding to an amide, any derivative of an oxoacid in which an acidic hydroxy group has been replaced by an amino or substituted amino group.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0051401	biolink:NamedThing	CH domain binding	Binding to a calponin homology protein domain, a domain of 100 residues that occurs in signaling and cytoskeletal proteins.	tmpzr1t_l9r_go_relaxed.owl	calponin homology domain binding													molecular_function											owl:Class	
GO:1904986	biolink:NamedThing	positive regulation of quinolinate biosynthetic process	Any process that activates or increases the frequency, rate or extent of quinolinate biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	activation of quinolinate biosynthesis|activation of quinolinate synthesis|up-regulation of quinolinate formation|up regulation of quinolinate biosynthesis|positive regulation of quinolinate synthesis|up regulation of quinolinate anabolism|up-regulation of quinolinate biosynthesis|up-regulation of quinolinate biosynthetic process|activation of quinolinate biosynthetic process|up regulation of quinolinate formation|upregulation of quinolinate anabolism|positive regulation of quinolinate anabolism|upregulation of quinolinate biosynthetic process|positive regulation of quinolinate biosynthesis|up-regulation of quinolinate anabolism|upregulation of quinolinate formation|up-regulation of quinolinate synthesis|positive regulation of quinolinate formation|up regulation of quinolinate synthesis|up regulation of quinolinate biosynthetic process|upregulation of quinolinate synthesis|activation of quinolinate anabolism|upregulation of quinolinate biosynthesis|activation of quinolinate formation							bf	2016-02-29T15:54:29Z					biological_process											owl:Class	
GO:0044787	biolink:NamedThing	bacterial-type DNA replication	The DNA-dependent DNA replication, exemplified by prokaryotes, that occurs as part of the cell cycle. Prokaryotic DNA replication is bi-directional and originates at a single origin of replication on the circular genome.	tmpzr1t_l9r_go_relaxed.owl	bacterial-type cell cycle DNA replication							jl	2013-05-02T15:54:16Z					biological_process											owl:Class	
GO:0031348	biolink:NamedThing	negative regulation of defense response	Any process that stops, prevents, or reduces the frequency, rate or extent of a defense response.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of defense response|inhibition of defense response|down regulation of defense response|downregulation of defense response													biological_process											owl:Class	
GO:0034997	biolink:NamedThing	alphav-beta5 integrin-vitronectin complex	A protein complex that comprises one integrin alphav subunit, one integrin beta5 subunit, and vitronectin.	tmpzr1t_l9r_go_relaxed.owl	ITGAV-ITGB5-VTN complex													cellular_component											owl:Class	
GO:0021813	biolink:NamedThing	cell-cell adhesion involved in neuronal-glial interactions involved in cerebral cortex radial glia guided migration	The interaction between two cells that modulates the association of a neuronal cell and a glial cell involved in glial-mediated radial cell migration in the cerebral cortex.	tmpzr1t_l9r_go_relaxed.owl	cell-cell adhesion involved in neuronal-glial interactions involved in cerebral cortex glial-mediated radial migration													biological_process											owl:Class	
GO:0098742	biolink:NamedThing	cell-cell adhesion via plasma-membrane adhesion molecules	The attachment of one cell to another cell via adhesion molecules that are at least partially embedded in the plasma membrane.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0039619	biolink:NamedThing	T=4 icosahedral viral capsid	The protein coat that surrounds the infective nucleic acid in some virus particles where the subunits (capsomeres) are arranged to form an icosahedron with T=4 symmetry. The T=4 capsid is composed of 12 pentameric and 30 hexameric capsomeres.	tmpzr1t_l9r_go_relaxed.owl					VZ:808			bf	2012-07-18T02:15:14Z					cellular_component											owl:Class	
GO:0019030	biolink:NamedThing	icosahedral viral capsid	The protein coat that surrounds the infective nucleic acid in some virus particles; the subunits are arranged to form an icosahedron, a solid with 20 faces and 12 vertices. Icosahedral capsids have 12 pentamers plus 10(T-1) hexamers, where T is the triangulation number. Tobacco satellite necrosis virus has such a capsid structure.	tmpzr1t_l9r_go_relaxed.owl	quasispherical viral capsid													cellular_component											owl:Class	
GO:0102070	biolink:NamedThing	18-hydroxyoleate peroxygenase activity	Catalysis of the reaction: 18-hydroxyoleate + a lipid hydroperoxide <=> 9,10-epoxy-18-hydroxystearate + a lipid alcohol.	tmpzr1t_l9r_go_relaxed.owl					EC:1.11.2.3|MetaCyc:RXN-1064									molecular_function											owl:Class	
GO:0016684	biolink:NamedThing	oxidoreductase activity, acting on peroxide as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which the peroxide group acts as a hydrogen or electron acceptor.	tmpzr1t_l9r_go_relaxed.owl					EC:1.11.-.-									molecular_function											owl:Class	
GO:0030621	biolink:NamedThing	U4 snRNA binding	Binding to a U4 small nuclear RNA (U4 snRNA).	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0060492	biolink:NamedThing	lung induction	The close range interaction of two or more cells or tissues that causes the cells of the foregut to change their fates and specify the development of the lung.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0001759	biolink:NamedThing	organ induction	The interaction of two or more cells or tissues that causes them to change their fates and specify the development of an organ.	tmpzr1t_l9r_go_relaxed.owl	induction of an organ													biological_process											owl:Class	
GO:0103016	biolink:NamedThing	tRNA-specific 2-thiouridylase activity	Catalysis of the reaction: ATP + H+ + a tRNA uridine34 + a [TusE sulfur carrier protein]-S-sulfanylcysteine = AMP + diphosphoric acid + a tRNA 2-thiouridine34 + a [TusE sulfur carrier protein]-L-cysteine.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN0-2023									molecular_function											owl:Class	
GO:0070050	biolink:NamedThing	neuron cellular homeostasis	The cellular homeostatic process that preserves a neuron in a stable, differentiated functional and structural state.	tmpzr1t_l9r_go_relaxed.owl	neuron maintenance													biological_process											owl:Class	
GO:0019743	biolink:NamedThing	hopanoid catabolic process	The chemical reactions and pathways resulting in the breakdown of hopanoids, pentacyclic sterol-like compounds based on the hopane nucleus.	tmpzr1t_l9r_go_relaxed.owl	hopanoid degradation|hopanoid breakdown|hopanoid catabolism													biological_process											owl:Class	
GO:0016105	biolink:NamedThing	triterpenoid catabolic process	The chemical reactions and pathways resulting in the breakdown of triterpenoid compounds, terpenoids with six isoprene units.	tmpzr1t_l9r_go_relaxed.owl	triterpene catabolism|triterpenoid catabolism|triterpene catabolic process|triterpenoid breakdown|triterpenoid degradation													biological_process											owl:Class	
GO:0014004	biolink:NamedThing	microglia differentiation	The process in which a relatively unspecialized cell acquires specialized features of a microglial cell. Microglia are glial cells that act as the immune cells of the central nervous system. They form part of the supporting structure of this system.	tmpzr1t_l9r_go_relaxed.owl	microglial cell differentiation													biological_process											owl:Class	
GO:0030225	biolink:NamedThing	macrophage differentiation	The process in which a relatively unspecialized monocyte acquires the specialized features of a macrophage.	tmpzr1t_l9r_go_relaxed.owl	macrophage cell differentiation													biological_process											owl:Class	
GO:0046863	biolink:NamedThing	ribulose-1,5-bisphosphate carboxylase/oxygenase activator activity	Increases the activity of rubisco by the removal of otherwise inhibitory sugar phosphates: RuBP, and in some plants, 2-carboxyarabinitol 1-phosphate.	tmpzr1t_l9r_go_relaxed.owl	rubisco activator|ribulose-bisphosphate carboxylase activase activity|rubisco activase activity|ribulose-1,5-bisphosphate carboxylase/oxygenase activase activity					See also the molecular function term 'ribulose-bisphosphate carboxylase activity ; GO:0016984'.						GO:0018236		molecular_function											owl:Class	
GO:0008047	biolink:NamedThing	enzyme activator activity	Binds to and increases the activity of an enzyme.	tmpzr1t_l9r_go_relaxed.owl	metalloenzyme activator activity					This term should only be used in cases when the regulator directly interacts with the enzyme.						GO:0010577		molecular_function											owl:Class	
GO:0043194	biolink:NamedThing	axon initial segment	Portion of the axon proximal to the neuronal cell body, at the level of the axon hillock. The action potentials that propagate along the axon are generated at the level of this initial segment.	tmpzr1t_l9r_go_relaxed.owl	initial segment				NIF_Subcellular:sao256000789									cellular_component											owl:Class	
GO:0071313	biolink:NamedThing	cellular response to caffeine	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a caffeine stimulus. Caffeine is an alkaloid found in numerous plant species, where it acts as a natural pesticide that paralyzes and kills certain insects feeding upon them.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-12-10T04:52:51Z					biological_process											owl:Class	
GO:0071415	biolink:NamedThing	cellular response to purine-containing compound	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a purine-containing compound stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to purine							mah	2009-12-14T03:12:20Z					biological_process											owl:Class	
GO:0001970	biolink:NamedThing	positive regulation of activation of membrane attack complex	Any process that activates, maintains or increases the frequency, rate or extent of the activation of the membrane attack complex components of the complement cascade.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of activation of the terminal complement cascade|positive regulation of MAC assembly|positive regulation of MAC formation|positive regulation of activation of TCC|positive regulation of membrane attack complex assembly|activation of activation of membrane attack complex|positive regulation of activation of terminal complement complex|upregulation of activation of membrane attack complex|up regulation of activation of membrane attack complex|positive regulation of activation of MAC|stimulation of activation of membrane attack complex|positive regulation of membrane attack complex formation|up-regulation of activation of membrane attack complex													biological_process											owl:Class	
GO:0062184	biolink:NamedThing	testosterone 16-beta-hydroxylase activity	Catalysis of the reaction: O2 + reduced [NADPH--hemoprotein reductase] + testosterone = 16beta,17beta-dihydroxyandrost-4-en-3-one + H(+) + H2O + oxidized [NADPH--hemoprotein reductase].	tmpzr1t_l9r_go_relaxed.owl					RHEA:46304			dph	2019-11-26T18:43:43Z					molecular_function											owl:Class	
GO:0004497	biolink:NamedThing	monooxygenase activity	Catalysis of the incorporation of one atom from molecular oxygen into a compound and the reduction of the other atom of oxygen to water.	tmpzr1t_l9r_go_relaxed.owl	hydroxylase activity				Reactome:R-HSA-76472|Reactome:R-HSA-6786239|Reactome:R-HSA-211924|Reactome:R-HSA-5423678|Reactome:R-HSA-5602272|Reactome:R-HSA-76354|Reactome:R-HSA-9027044|Reactome:R-HSA-76386|Reactome:R-HSA-5602242|Reactome:R-HSA-211991|Reactome:R-HSA-5423672|Reactome:R-HSA-2161890|Reactome:R-HSA-2161899|Reactome:R-HSA-2162191|Reactome:R-HSA-212005|Reactome:R-HSA-76466|Reactome:R-HSA-76373|Reactome:R-HSA-9027043|Reactome:R-HSA-5663050|Reactome:R-HSA-2161814|Reactome:R-HSA-5605147|Reactome:R-HSA-76426|Reactome:R-HSA-8865107|Reactome:R-HSA-213175|Reactome:R-HSA-9027042|Reactome:R-HSA-76475|Reactome:R-HSA-211904|Reactome:R-HSA-9037761|Reactome:R-HSA-76397|Reactome:R-HSA-211988|Reactome:R-HSA-211910|Reactome:R-HSA-9027302|Reactome:R-HSA-2161940|Reactome:R-HSA-211951|Reactome:R-HSA-9018874|Reactome:R-HSA-5662692|Reactome:R-HSA-217258|Reactome:R-HSA-5423664|Reactome:R-HSA-211882|Reactome:R-HSA-76434|Reactome:R-HSA-143468|Reactome:R-HSA-211948|Reactome:R-HSA-76416|Reactome:R-HSA-76456|Reactome:R-HSA-5602295|Reactome:R-HSA-215526|Reactome:R-HSA-211959|Reactome:R-HSA-156526|Reactome:R-HSA-211919|Reactome:R-HSA-211929|Reactome:R-HSA-211962|Reactome:R-HSA-211968|Reactome:R-HSA-5662662|Reactome:R-HSA-5423647|Reactome:R-HSA-212004|Reactome:R-HSA-2161795|Reactome:R-HSA-9027321|Reactome:R-HSA-211960									molecular_function											owl:Class	
GO:0071741	biolink:NamedThing	IgD immunoglobulin complex, GPI-anchored	A protein complex composed of two identical immunoglobulin heavy chains of the IgD isotype and two identical immunoglobulin light chains, held together by disulfide bonds, and bound via a GPI-anchor to the plasma membrane of B cells.	tmpzr1t_l9r_go_relaxed.owl	GPI-anchored IgD					Note that an IgD immunoglobulin complex has the function of antigen binding if a suitable antigen is available.		mah	2010-03-24T01:44:53Z					cellular_component											owl:Class	
GO:0071738	biolink:NamedThing	IgD immunoglobulin complex	A protein complex composed of two identical immunoglobulin heavy chains of the IgD isotype and two identical immunoglobulin light chains, held together by disulfide bonds. An IgD immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.	tmpzr1t_l9r_go_relaxed.owl						Note that an IgD immunoglobulin complex has the function of antigen binding if a suitable antigen is available.		mah	2010-03-24T01:44:53Z					cellular_component											owl:Class	
GO:0032831	biolink:NamedThing	positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation	Any process that activates or increases the frequency, rate or extent of differentiation of CD4-positive, CD25-positive, alpha-beta regulatory T cells.	tmpzr1t_l9r_go_relaxed.owl	upregulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation|positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T-cell differentiation|activation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation|up-regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation|up regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation|positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T lymphocyte differentiation|stimulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation|positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T-lymphocyte differentiation|positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell development					Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.								biological_process											owl:Class	
GO:0045591	biolink:NamedThing	positive regulation of regulatory T cell differentiation	Any process that activates or increases the frequency, rate or extent of differentiation of regulatory T cells.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of suppressor T-cell differentiation|up regulation of regulatory T cell differentiation|positive regulation of regulatory T-lymphocyte differentiation|activation of regulatory T cell differentiation|stimulation of regulatory T cell differentiation|up-regulation of regulatory T cell differentiation|positive regulation of regulatory T cell development|positive regulation of regulatory T lymphocyte differentiation|positive regulation of suppressor T cell differentiation|positive regulation of regulatory T-cell differentiation|upregulation of regulatory T cell differentiation					Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.								biological_process											owl:Class	
GO:0047116	biolink:NamedThing	1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase activity	Catalysis of the reaction: NAD+ + 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate = NADH + CO2 + catechol.	tmpzr1t_l9r_go_relaxed.owl	cis-1,2-dihydroxycyclohexa-3,5-diene-1-carboxylate:NAD(+) oxidoreductase activity|(1R,6R)-1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate:NAD+ oxidoreductase (decarboxylating)|2-hydro-1,2-dihydroxybenzoate dehydrogenase activity|dihydrodihydroxybenzoate dehydrogenase activity|3,5-cyclohexadiene-1,2-diol-1-carboxylate dehydrogenase activity|DHB dehydrogenase activity|cis-1,2-dihydroxycyclohexa-3,5-diene-1-carboxylate:NAD+ oxidoreductase activity|DHBDH activity|3,5-cyclohexadiene-1,2-diol-1-carboxylic acid dehydrogenase activity				MetaCyc:1.3.1.25-RXN|RHEA:11560|EC:1.3.1.25									molecular_function											owl:Class	
GO:0140567	biolink:NamedThing	transmembrane protein dislocase activity	The activity of removing a protein from a membrane, by binding to a transmembrane helical fragment of a tail-anchored protein and releasing it from the the hydrophobic region of one or both lipid bilayers. The reaction is driven by ATP hydrolysis.	tmpzr1t_l9r_go_relaxed.owl	transmembrane helix dislocase	https://github.com/geneontology/go-ontology/issues/20237|https://github.com/geneontology/go-ontology/issues/22209			RHEA:66168			pg	2020-12-15T07:13:21Z					molecular_function											owl:Class	
GO:0140657	biolink:NamedThing	ATP-dependent activity	A molecular function characterized by the coupling of ATP hydrolysis to other steps of a reaction mechanism to make the reaction energetically favorable, for example to catalyze a reaction or drive transport against a concentration gradient.	tmpzr1t_l9r_go_relaxed.owl	ATPase-dependent activity|ATP hydrolysis-dependent activity|ATPase activity, coupled|ATPase activity	https://github.com/geneontology/go-ontology/issues/22371|https://github.com/geneontology/go-ontology/issues/21612				Note that this term represents a grouping class that includes all proteins that use ATP hydrolysis to drive a reaction; it is not meant to capture the ATP hydrolysis reaction itself. To annotate ATP hydrolysis, please use 'ATP hydrolysis activity ; GO:0016887'.		pg	2021-06-15T07:35:06Z					molecular_function											owl:Class	
GO:0035331	biolink:NamedThing	negative regulation of hippo signaling	Any process that stops, prevents, or reduces the frequency, rate or extent of hippo signaling.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of hippo signalling cascade|negative regulation of hippo signaling cascade|negative regulation of hippo signaling pathway							bf	2010-02-26T10:54:19Z					biological_process											owl:Class	
GO:1901909	biolink:NamedThing	diadenosine hexaphosphate catabolic process	The chemical reactions and pathways resulting in the breakdown of diadenosine hexaphosphate.	tmpzr1t_l9r_go_relaxed.owl	diadenosyl hexaphosphate breakdown|diadenosyl hexaphosphate catabolism|diadenosine hexaphosphate catabolism|diadenosyl hexaphosphate catabolic process|diadenosyl hexaphosphate degradation							al	2013-02-13T13:50:44Z					biological_process											owl:Class	
GO:0015961	biolink:NamedThing	diadenosine polyphosphate catabolic process	The chemical reactions and pathways resulting in the breakdown of diadenosine polyphosphate, a derivative of the nucleoside adenosine with phosphate groups attached.	tmpzr1t_l9r_go_relaxed.owl	diadenosine polyphosphate breakdown|diadenosine polyphosphate catabolism|diadenosine polyphosphate degradation													biological_process											owl:Class	
GO:2000519	biolink:NamedThing	positive regulation of T-helper 1 cell activation	Any process that activates or increases the frequency, rate or extent of T-helper 1 cell activation.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of Th1 cell activation							ebc	2011-03-22T10:40:31Z					biological_process											owl:Class	
GO:2000517	biolink:NamedThing	regulation of T-helper 1 cell activation	Any process that modulates the frequency, rate or extent of T-helper 1 cell activation.	tmpzr1t_l9r_go_relaxed.owl	regulation of Th1 cell activation							ebc	2011-03-22T10:40:19Z					biological_process											owl:Class	
GO:0102037	biolink:NamedThing	4-nitrotoluene monooxygenase activity	Catalysis of the reaction: H+ + 4-nitrotoluene + NADH + O2 <=> 4-nitrobenzyl alcohol + NAD+ + H2O.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:R361-RXN									molecular_function											owl:Class	
GO:0072157	biolink:NamedThing	epithelial cell migration involved in distal tubule morphogenesis	The orderly movement of epithelial cells within a renal tubule that contributes to distal tubule morphogenesis.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-02-24T02:33:33Z					biological_process											owl:Class	
GO:0007290	biolink:NamedThing	spermatid nucleus elongation	The change in shape of the spermatid nucleus from a spherical structure to an elongated organelle, during the latter part of spermatid differentiation.	tmpzr1t_l9r_go_relaxed.owl	spermatid nuclear elongation													biological_process											owl:Class	
GO:2000480	biolink:NamedThing	negative regulation of cAMP-dependent protein kinase activity	Any process that stops, prevents or reduces the frequency, rate or extent of cAMP-dependent protein kinase activity.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of PKA|negative regulation of protein kinase A activity|negative regulation of 3',5'-cAMP-dependent protein kinase activity|negative regulation of cAMP-dependent protein kinase, intrinsic catalyst activity|negative regulation of PKA C|negative regulation of STK22|negative regulation of AMPK|negative regulation of cyclic AMP-dependent protein kinase activity|negative regulation of adenosine 3',5'-cyclophosphate-dependent protein kinase activity|negative regulation of 3',5' cAMP-dependent protein kinase activity|negative regulation of ATP:protein phosphotransferase (cAMP-dependent) activity							yaf	2011-03-10T11:13:45Z					biological_process											owl:Class	
GO:2000479	biolink:NamedThing	regulation of cAMP-dependent protein kinase activity	Any process that modulates the frequency, rate or extent of cAMP-dependent protein kinase activity.	tmpzr1t_l9r_go_relaxed.owl	regulation of ATP:protein phosphotransferase (cAMP-dependent) activity|regulation of PKA C|regulation of 3',5'-cAMP-dependent protein kinase activity|regulation of adenosine 3',5'-cyclophosphate-dependent protein kinase activity|regulation of protein kinase A activity|regulation of 3',5' cAMP-dependent protein kinase activity|regulation of AMPK|regulation of cyclic AMP-dependent protein kinase activity|regulation of cAMP-dependent protein kinase, intrinsic catalyst activity|regulation of PKA|regulation of STK22							yaf	2011-03-10T11:13:01Z					biological_process											owl:Class	
GO:0032951	biolink:NamedThing	regulation of beta-glucan biosynthetic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways relusting in the formation of beta-glucans.	tmpzr1t_l9r_go_relaxed.owl	regulation of beta-glucan biosynthesis|regulation of beta-glucan anabolism|regulation of beta-glucan synthesis|regulation of beta-glucan formation													biological_process											owl:Class	
GO:0010962	biolink:NamedThing	regulation of glucan biosynthetic process	Any process that modulates the rate, frequency, or extent of glucan biosynthesis. Glucan biosynthetic processes are the chemical reactions and pathways resulting in the formation of glucans, polysaccharides consisting only of glucose residues.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-05-11T12:17:53Z					biological_process											owl:Class	
GO:2000992	biolink:NamedThing	negative regulation of galactomannan catabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of galactomannan catabolic process.	tmpzr1t_l9r_go_relaxed.owl								tt	2011-08-08T03:16:00Z					biological_process											owl:Class	
GO:1990876	biolink:NamedThing	cytoplasmic side of nuclear pore	The side of the nuclear pore complex (NPC) that faces the cytoplasm.	tmpzr1t_l9r_go_relaxed.owl	cytoplasmic side of nucleopore|cytoplasmic side of NPC|cytoplasmic side of nuclear pore complex							sl	2015-10-01T21:47:54Z					cellular_component											owl:Class	
GO:0031329	biolink:NamedThing	regulation of cellular catabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells.	tmpzr1t_l9r_go_relaxed.owl	regulation of cellular degradation|regulation of cellular catabolism|regulation of cellular breakdown													biological_process											owl:Class	
GO:1904128	biolink:NamedThing	negative regulation of convergent extension involved in somitogenesis	Any process that stops, prevents or reduces the frequency, rate or extent of convergent extension involved in somitogenesis.	tmpzr1t_l9r_go_relaxed.owl	downregulation of convergent extension involved in somitogenesis|down-regulation of convergent extension involved in somitogenesis|inhibition of convergent extension involved in somitogenesis|down regulation of convergent extension involved in somitogenesis							dph	2015-04-10T21:13:10Z					biological_process											owl:Class	
GO:1904127	biolink:NamedThing	regulation of convergent extension involved in somitogenesis	Any process that modulates the frequency, rate or extent of convergent extension involved in somitogenesis.	tmpzr1t_l9r_go_relaxed.owl								dph	2015-04-10T21:13:04Z					biological_process											owl:Class	
GO:0032821	biolink:NamedThing	negative regulation of natural killer cell proliferation involved in immune response	Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer cell proliferation as part of an immune response.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of natural killer cell proliferation during immune response|downregulation of natural killer cell proliferation during immune response|down regulation of natural killer cell proliferation during immune response|inhibition of natural killer cell proliferation during immune response|down-regulation of natural killer cell proliferation during immune response|negative regulation of NK cell proliferation during immune response													biological_process											owl:Class	
GO:0002698	biolink:NamedThing	negative regulation of immune effector process	Any process that stops, prevents, or reduces the frequency, rate, or extent of an immune effector process.	tmpzr1t_l9r_go_relaxed.owl	down regulation of immune effector process|inhibition of immune effector process|downregulation of immune effector process|down-regulation of immune effector process													biological_process											owl:Class	
GO:0098711	biolink:NamedThing	iron ion import across plasma membrane	The directed movement of iron ions from outside of a cell, across the plasma membrane and into the cytosol.	tmpzr1t_l9r_go_relaxed.owl	iron import into cell|iron ion import into cell|ferrous ion import into cell|ferrous iron import across plasma membrane|ferrous iron import into cell							pr	2012-12-20T08:29:00Z			GO:0097460|GO:0098707|GO:0097459		biological_process											owl:Class	
GO:0071357	biolink:NamedThing	cellular response to type I interferon	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a type I interferon stimulus. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families.	tmpzr1t_l9r_go_relaxed.owl	cellular response to type I IFN							mah	2009-12-11T02:51:47Z					biological_process											owl:Class	
GO:0002552	biolink:NamedThing	serotonin secretion by mast cell	The regulated release of serotonin by a mast cell or group of mast cells.	tmpzr1t_l9r_go_relaxed.owl	serotonin release by mast cell													biological_process											owl:Class	
GO:0002442	biolink:NamedThing	serotonin secretion involved in inflammatory response	The regulated release of serotonin by a cell as part of an inflammatory response.	tmpzr1t_l9r_go_relaxed.owl	serotonin release involved in inflammatory response|serotonin secretion involved in acute inflammatory response													biological_process											owl:Class	
GO:0071977	biolink:NamedThing	bacterial-type flagellum-dependent swimming motility	Bacterial-type flagellum-dependent cell motility that results in the smooth movement of a cell through a liquid medium.	tmpzr1t_l9r_go_relaxed.owl	bacterial-type flagellum-mediated cell swimming|bacterial-type flagellar swimming motility							mah	2010-10-21T02:58:51Z					biological_process											owl:Class	
GO:0071975	biolink:NamedThing	cell swimming	Cell motility that results in the smooth movement of a cell through a liquid medium.	tmpzr1t_l9r_go_relaxed.owl	cell swimming motility							mah	2010-10-21T02:31:34Z					biological_process											owl:Class	
GO:1900659	biolink:NamedThing	negative regulation of emericellamide biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of emericellamide biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of emericellamide biosynthesis|negative regulation of emericellamide synthesis|down regulation of emericellamide biosynthetic process|downregulation of emericellamide biosynthetic process|downregulation of emericellamide synthesis|down regulation of emericellamide formation|inhibition of emericellamide biosynthesis|negative regulation of emericellamide biosynthesis|down-regulation of emericellamide formation|down regulation of emericellamide anabolism|negative regulation of emericellamide formation|downregulation of emericellamide formation|down-regulation of emericellamide biosynthetic process|down regulation of emericellamide synthesis|downregulation of emericellamide biosynthesis|down-regulation of emericellamide anabolism|down-regulation of emericellamide synthesis|downregulation of emericellamide anabolism|inhibition of emericellamide anabolism|down regulation of emericellamide biosynthesis|inhibition of emericellamide formation|inhibition of emericellamide synthesis|inhibition of emericellamide biosynthetic process|negative regulation of emericellamide anabolism							di	2012-05-22T04:10:44Z					biological_process											owl:Class	
GO:0034249	biolink:NamedThing	negative regulation of cellular amide metabolic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving amides.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of amide metabolism													biological_process											owl:Class	
GO:0034697	biolink:NamedThing	response to prostaglandin I	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin I stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to prostaglandin I stimulus													biological_process											owl:Class	
GO:0061922	biolink:NamedThing	histone propionyltransferase activity	Catalysis of the reaction: propionyl-CoA + histone = CoA + propionyl-histone.	tmpzr1t_l9r_go_relaxed.owl								dph	2017-08-02T13:38:50Z					molecular_function											owl:Class	
GO:0061920	biolink:NamedThing	protein propionyltransferase activity	Catalysis of the reaction: propionyl-CoA + lysine in peptide = CoA + N-propionyl-lysine-peptide.	tmpzr1t_l9r_go_relaxed.owl								dph	2017-08-02T13:35:22Z					molecular_function											owl:Class	
GO:1902742	biolink:NamedThing	apoptotic process involved in development	Any apoptotic process that is involved in anatomical structure development.	tmpzr1t_l9r_go_relaxed.owl	programmed cell death by apoptosis involved in development of an anatomical structure|induction of apoptosis involved in development of an anatomical structure|type I programmed cell death involved in anatomical structure development|apoptotic cell death involved in development of an anatomical structure|apoptotic process involved in anatomical structure development|apoptotic programmed cell death involved in development of an anatomical structure|type I programmed cell death involved in development of an anatomical structure|activation of apoptosis involved in development of an anatomical structure|apoptotic program involved in development of an anatomical structure|programmed cell death by apoptosis involved in anatomical structure development|signaling (initiator) caspase activity involved in development of an anatomical structure|apoptosis involved in anatomical structure development|apoptosis signaling involved in anatomical structure development|activation of apoptosis involved in anatomical structure development|apoptotic program involved in anatomical structure development|apoptosis involved in development of an anatomical structure|apoptotic programmed cell death involved in anatomical structure development|apoptotic cell death involved in anatomical structure development|induction of apoptosis involved in anatomical structure development|commitment to apoptosis involved in anatomical structure development|apoptosis activator activity involved in development of an anatomical structure|commitment to apoptosis involved in development of an anatomical structure|induction of apoptosis by p53 involved in development of an anatomical structure|apoptotic process involved in development of an anatomical structure|apoptosis activator activity involved in anatomical structure development|induction of apoptosis by p53 involved in anatomical structure development|apoptosis signaling involved in development of an anatomical structure|signaling (initiator) caspase activity involved in anatomical structure development							pr	2014-02-28T13:09:43Z					biological_process											owl:Class	
GO:1903633	biolink:NamedThing	regulation of leucine-tRNA ligase activity	Any process that modulates the frequency, rate or extent of leucine-tRNA ligase activity.	tmpzr1t_l9r_go_relaxed.owl	regulation of leucyl-transfer RNA synthetase activity|regulation of leucyl-transfer ribonucleic acid synthetase activity|regulation of leucyl-tRNA synthetase activity|regulation of leucine translase activity|regulation of L-leucine:tRNALeu ligase (AMP-forming)|regulation of leucyl-transfer ribonucleate synthetase activity|regulation of leucine-tRNA synthetase activity							sl	2014-11-20T00:24:48Z					biological_process											owl:Class	
GO:1904579	biolink:NamedThing	cellular response to thapsigargin	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a thapsigargin stimulus.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-08-19T18:06:28Z					biological_process											owl:Class	
GO:0071550	biolink:NamedThing	death-inducing signaling complex assembly	A process of protein complex assembly in which the arrangement and bonding together of the set of components that form the protein complex is mediated by a death domain (DD) interaction, as part of the extrinsic apoptotic signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	death domain-mediated complex assembly involved in extrinsic apoptotic pathway|DD-mediated complex assembly|DISC formation|death domain-mediated complex assembly|death-inducing signalling complex assembly|DISC assembly|death-inducing signaling complex formation							mah	2010-01-13T02:48:38Z					biological_process											owl:Class	
GO:0065003	biolink:NamedThing	protein-containing complex assembly	The aggregation, arrangement and bonding together of a set of macromolecules to form a protein-containing complex.	tmpzr1t_l9r_go_relaxed.owl	chaperone activity|protein complex assembly|macromolecular complex assembly|macromolecule complex assembly|protein complex formation											GO:0006461		biological_process											owl:Class	
GO:0047109	biolink:NamedThing	(S)-3-hydroxyacid-ester dehydrogenase activity	Catalysis of the reaction: ethyl (S)-3-hydroxyhexanoate + NADP(+) = ethyl 3-oxohexanoate + H(+) + NADPH.	tmpzr1t_l9r_go_relaxed.owl	(S)-3-hydroxyacid ester dehydrogenase activity|3-oxo ester (S)-reductase activity|ethyl-(S)-3-hydroxyhexanoate:NADP+ 3-oxidoreductase activity				KEGG_REACTION:R04106|MetaCyc:1.2.1.56-RXN|EC:1.1.1.280|RHEA:18269	Note that this term was EC:1.2.1.56.								molecular_function											owl:Class	
GO:1901522	biolink:NamedThing	positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus	Any positive regulation of transcription from RNA polymerase II promoter that is involved in cellular response to chemical stimulus.	tmpzr1t_l9r_go_relaxed.owl	activation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus|up-regulation of global transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus|activation of global transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus|up regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus|positive regulation of transcription from Pol II promoter involved in cellular response to chemical stimulus|stimulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus|stimulation of global transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus|upregulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus|up-regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus|positive regulation of gene-specific transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus|upregulation of global transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus|up regulation of global transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus|positive regulation of global transcription from Pol II promoter involved in cellular response to chemical stimulus							al	2012-10-19T08:25:05Z					biological_process											owl:Class	
GO:0009062	biolink:NamedThing	fatty acid catabolic process	The chemical reactions and pathways resulting in the breakdown of a fatty acid, any of the aliphatic monocarboxylic acids that can be liberated by hydrolysis from naturally occurring fats and oils. Fatty acids are predominantly straight-chain acids of 4 to 24 carbon atoms, which may be saturated or unsaturated; branched fatty acids and hydroxy fatty acids also occur, and very long chain acids of over 30 carbons are found in waxes.	tmpzr1t_l9r_go_relaxed.owl	fatty acid catabolism|fatty acid breakdown|fatty acid degradation				Wikipedia:Fatty_acid_degradation									biological_process											owl:Class	
GO:0006631	biolink:NamedThing	fatty acid metabolic process	The chemical reactions and pathways involving fatty acids, aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis.	tmpzr1t_l9r_go_relaxed.owl	fatty acid metabolism				Wikipedia:Fatty_acid_metabolism									biological_process											owl:Class	
GO:1901179	biolink:NamedThing	spheroidene catabolic process	The chemical reactions and pathways resulting in the breakdown of spheroidene.	tmpzr1t_l9r_go_relaxed.owl	spheroidene breakdown|spheroidene degradation|spheroidene catabolism							yaf	2012-07-19T09:49:14Z					biological_process											owl:Class	
GO:1901178	biolink:NamedThing	spheroidene metabolic process	The chemical reactions and pathways involving spheroidene.	tmpzr1t_l9r_go_relaxed.owl	spheroidene metabolism							yaf	2012-07-19T09:48:54Z					biological_process											owl:Class	
GO:0034235	biolink:NamedThing	GPI anchor binding	Binding to a glycosylphosphatidylinositol anchor. GPI anchors serve to attach membrane proteins to the lipid bilayer of cell membranes.	tmpzr1t_l9r_go_relaxed.owl	glycosylphosphatidylinositol binding					Note that this term should be used to annotate gene products that interact non-covalently with GPI anchors, and not proteins that have GPI anchors covalently attached.								molecular_function											owl:Class	
GO:0051861	biolink:NamedThing	glycolipid binding	Binding to a glycolipid, any compound containing one or more monosaccharide residues bound by a glycosidic linkage to a hydrophobic group such as an acylglycerol, a sphingoid, a ceramide (N-acylsphingoid) or a prenyl phosphate.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0010419	biolink:NamedThing	rhamnogalacturonan II side chain metabolic process	The chemical reactions and pathways involving the side chains of pectic rhamnogalacturonan II. A number of structurally distinct di- and oligosaccharides can be attached to the C-3 and C-2 of the backbone, respectively.	tmpzr1t_l9r_go_relaxed.owl	rhamnogalacturonan II side chain metabolism													biological_process											owl:Class	
GO:0019177	biolink:NamedThing	dihydroneopterin triphosphate pyrophosphohydrolase activity	Catalysis of the reaction: dihydroneopterin triphosphate = dihydroneopterin phosphate + diphosphate.	tmpzr1t_l9r_go_relaxed.owl					RHEA:25302|MetaCyc:H2NEOPTERINP3PYROPHOSPHOHYDRO-RXN									molecular_function											owl:Class	
GO:2000761	biolink:NamedThing	positive regulation of N-terminal peptidyl-lysine acetylation	Any process that activates or increases the frequency, rate or extent of N-terminal peptidyl-lysine acetylation.	tmpzr1t_l9r_go_relaxed.owl								yaf	2011-06-17T12:58:24Z					biological_process											owl:Class	
GO:2000759	biolink:NamedThing	regulation of N-terminal peptidyl-lysine acetylation	Any process that modulates the frequency, rate or extent of N-terminal peptidyl-lysine acetylation.	tmpzr1t_l9r_go_relaxed.owl								yaf	2011-06-17T12:58:16Z					biological_process											owl:Class	
GO:0046479	biolink:NamedThing	glycosphingolipid catabolic process	The chemical reactions and pathways resulting in the breakdown of glycosphingolipid, a compound with residues of sphingoid and at least one monosaccharide.	tmpzr1t_l9r_go_relaxed.owl	glycosphingolipid catabolism|glycosphingolipid breakdown|glycosphingolipid degradation													biological_process											owl:Class	
GO:0019377	biolink:NamedThing	glycolipid catabolic process	The chemical reactions and pathways resulting in the breakdown of glycolipid, a class of 1,2-di-O-acylglycerols joined at oxygen 3 by a glycosidic linkage to a carbohydrate part (usually a mono-, di- or tri-saccharide).	tmpzr1t_l9r_go_relaxed.owl	glycolipid breakdown|glycolipid degradation|glycolipid catabolism													biological_process											owl:Class	
GO:0010595	biolink:NamedThing	positive regulation of endothelial cell migration	Any process that increases the rate, frequency, or extent of the orderly movement of an endothelial cell into the extracellular matrix to form an endothelium.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0010634	biolink:NamedThing	positive regulation of epithelial cell migration	Any process that activates or increases the frequency, rate or extent of epithelial cell migration.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0106062	biolink:NamedThing	positive regulation of exit from meiosis	Any process that activates or increases the frequency, rate or extent of exit from meiosis.	tmpzr1t_l9r_go_relaxed.owl								hjd	2017-10-18T16:57:01Z					biological_process											owl:Class	
GO:1900486	biolink:NamedThing	positive regulation of isopentenyl diphosphate biosynthetic process, mevalonate pathway	Any process that activates or increases the frequency, rate or extent of isopentenyl diphosphate biosynthetic process, mevalonate pathway.	tmpzr1t_l9r_go_relaxed.owl	activation of Ac-MVA pathway|up regulation of isopentenyl diphosphate biosynthetic process, mevalonate pathway|positive regulation of isopentenyl diphosphate anabolism, mevalonate pathway|activation of isopentenyl diphosphate synthesis, mevalonate pathway|positive regulation of acetate-mevalonate pathway|activation of isopentenyl diphosphate biosynthetic process, mevalonate pathway|upregulation of isopentenyl diphosphate anabolism, mevalonate pathway|positive regulation of Ac-MVA pathway|upregulation of acetate-mevalonate pathway|upregulation of isopentenyl diphosphate biosynthetic process, mevalonate pathway|up-regulation of acetate-mevalonate pathway|upregulation of isopentenyl diphosphate synthesis, mevalonate pathway|up regulation of isopentenyl diphosphate formation, mevalonate pathway|activation of isopentenyl diphosphate anabolism, mevalonate pathway|positive regulation of isopentenyl diphosphate formation, mevalonate pathway|up-regulation of isopentenyl diphosphate formation, mevalonate pathway|up-regulation of Ac-MVA pathway|upregulation of Ac-MVA pathway|up-regulation of isopentenyl diphosphate anabolism, mevalonate pathway|positive regulation of isopentenyl diphosphate synthesis, mevalonate pathway|up regulation of isopentenyl diphosphate anabolism, mevalonate pathway|activation of acetate-mevalonate pathway|upregulation of isopentenyl diphosphate formation, mevalonate pathway|up-regulation of isopentenyl diphosphate synthesis, mevalonate pathway|up-regulation of isopentenyl diphosphate biosynthetic process, mevalonate pathway|up regulation of acetate-mevalonate pathway|up regulation of isopentenyl diphosphate synthesis, mevalonate pathway|activation of isopentenyl diphosphate formation, mevalonate pathway|up regulation of Ac-MVA pathway							al	2012-05-02T10:46:46Z					biological_process											owl:Class	
GO:2001210	biolink:NamedThing	regulation of isopentenyl diphosphate biosynthetic process, mevalonate pathway	Any process that modulates the frequency, rate or extent of isopentenyl diphosphate biosynthetic process, mevalonate pathway.	tmpzr1t_l9r_go_relaxed.owl	regulation of isopentenyl diphosphate formation, mevalonate pathway|regulation of isopentenyl diphosphate synthesis, mevalonate pathway|regulation of acetate-mevalonate pathway|regulation of Ac-MVA pathway|regulation of isopentenyl diphosphate anabolism, mevalonate pathway							bf	2011-11-15T10:53:42Z					biological_process											owl:Class	
GO:1901304	biolink:NamedThing	regulation of spermidine biosynthetic process	Any process that modulates the frequency, rate or extent of spermidine biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of spermidine biosynthesis|regulation of spermidine anabolism|regulation of spermidine formation|regulation of spermidine synthesis							pm	2012-08-21T13:58:23Z					biological_process											owl:Class	
GO:0031976	biolink:NamedThing	plastid thylakoid	Any thylakoid within a plastid.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0009579	biolink:NamedThing	thylakoid	A membranous cellular structure that bears the photosynthetic pigments in plants, algae, and cyanobacteria. In cyanobacteria thylakoids are of various shapes and are attached to, or continuous with, the plasma membrane. In eukaryotes they are flattened, membrane-bounded disk-like structures located in the chloroplasts; in the chloroplasts of higher plants the thylakoids form dense stacks called grana. Isolated thylakoid preparations can carry out photosynthetic electron transport and the associated phosphorylation.	tmpzr1t_l9r_go_relaxed.owl	photosynthetic membrane				Wikipedia:Thylakoid	A thylakoid is not considered an organelle, but some thylakoids are part of organelles.								cellular_component											owl:Class	
GO:1903479	biolink:NamedThing	mitotic actomyosin contractile ring assembly actin filament organization	Any actin filament organization that is involved in mitotic actomyosin contractile ring assembly.	tmpzr1t_l9r_go_relaxed.owl	actin filament organisation involved in contractile ring assembly involved in mitotic cytokinesis|actin filament organisation involved in mitotic actomyosin contractile ring assembly|actin filament organization involved in mitotic actomyosin contractile ring assembly							vw	2014-09-23T15:03:19Z					biological_process											owl:Class	
GO:0018934	biolink:NamedThing	nitrilotriacetate metabolic process	The chemical reactions and pathways involving nitrilotriacetate, an aminotricarboxylic acid that binds bivalent metal ions in a ratio of 1:1. As an important industrial chelating agent, NTA has been widely used for various radionuclide processing and decontamination procedures, such as textile, paper and pulp processing and water treatment.	tmpzr1t_l9r_go_relaxed.owl	nitrilotriacetate metabolism				UM-BBD_pathwayID:nta									biological_process											owl:Class	
GO:0009616	biolink:NamedThing	RNAi-mediated antiviral immune response	RNA-mediated post-transcriptional gene silencing mechanism that protects against foreign organism invasion by restricting viral replication and dissemination.	tmpzr1t_l9r_go_relaxed.owl	virus induced gene silencing|VIGS|viral triggering of virus induced gene silencing|virus-induced gene silencing|viral gene silencing in virus induced gene silencing|RNAi-mediated antiviral immunity	https://github.com/geneontology/go-ontology/issues/19958				Virus induced gene silencing (VIGS) is used as a technique to control plant gene expression; when used in that context, this does not represent a normal biological process and is outside the scope of GO.						GO:0060145|GO:0060150		biological_process											owl:Class	
GO:0045087	biolink:NamedThing	innate immune response	Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens.	tmpzr1t_l9r_go_relaxed.owl	innate immunity|nonspecific immune response				Wikipedia:Innate_immune_system							GO:0002226		biological_process											owl:Class	
GO:1905083	biolink:NamedThing	negative regulation of mitochondrial translational elongation	Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrial translational elongation.	tmpzr1t_l9r_go_relaxed.owl	inhibition of mitochondrial translational elongation|downregulation of mitochondrial translation elongation|downregulation of mitochondrial translational elongation|down regulation of mitochondrial translation elongation|negative regulation of mitochondrial translation elongation|down-regulation of mitochondrial translation elongation|down regulation of mitochondrial translational elongation|down-regulation of mitochondrial translational elongation|inhibition of mitochondrial translation elongation							hjd	2016-03-25T17:37:13Z					biological_process											owl:Class	
GO:0032594	biolink:NamedThing	protein transport within lipid bilayer	The directed movement of a protein from one location to another within a lipid bilayer.	tmpzr1t_l9r_go_relaxed.owl	receptor transport within lipid bilayer|receptor translocation within membrane|protein translocation within membrane													biological_process											owl:Class	
GO:0006886	biolink:NamedThing	intracellular protein transport	The directed movement of proteins in a cell, including the movement of proteins between specific compartments or structures within a cell, such as organelles of a eukaryotic cell.	tmpzr1t_l9r_go_relaxed.owl	copper-induced intracellular protein transport											GO:0032779		biological_process											owl:Class	
GO:0097068	biolink:NamedThing	response to thyroxine	A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a thyroxine stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to thyroxine stimulus|response to T4 stimulus|response to T4							pr	2011-06-14T05:05:07Z					biological_process											owl:Class	
GO:0097066	biolink:NamedThing	response to thyroid hormone	A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a thyroid hormone stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to thyroid hormone stimulus							pr	2011-06-14T05:01:18Z					biological_process											owl:Class	
GO:1990601	biolink:NamedThing	5' overhang single-stranded DNA endodeoxyribonuclease activity	Catalysis of the hydrolysis of ester linkages within 5' overhang single-stranded deoxyribonucleic acid by creating internal breaks.	tmpzr1t_l9r_go_relaxed.owl								al	2015-01-06T16:24:39Z					molecular_function											owl:Class	
GO:0000014	biolink:NamedThing	single-stranded DNA endodeoxyribonuclease activity	Catalysis of the hydrolysis of ester linkages within a single-stranded deoxyribonucleic acid molecule by creating internal breaks.	tmpzr1t_l9r_go_relaxed.owl	single-stranded DNA specific endodeoxyribonuclease activity|ssDNA-specific endodeoxyribonuclease activity													molecular_function											owl:Class	
GO:1902444	biolink:NamedThing	riboflavin binding	Binding to riboflavin.	tmpzr1t_l9r_go_relaxed.owl								al	2013-10-11T08:44:52Z					molecular_function											owl:Class	
GO:1904317	biolink:NamedThing	cellular response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to platelet-activating factor|cellular response to PAF							sl	2015-06-10T18:10:23Z					biological_process											owl:Class	
GO:1904316	biolink:NamedThing	response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to PAF|response to platelet-activating factor							sl	2015-06-10T18:10:17Z					biological_process											owl:Class	
GO:0018304	biolink:NamedThing	iron incorporation into iron-sulfur cluster via tris-L-cysteinyl-L-aspartato tetrairon tetrasulfide	The incorporation of iron into a 4Fe-4S iron-sulfur cluster via tris-L-cysteinyl-L-aspartato tetrairon tetrasulfide.	tmpzr1t_l9r_go_relaxed.owl	iron incorporation into iron-sulphur cluster via tris-L-cysteinyl-L-aspartato tetrairon tetrasulphide				RESID:AA0286									biological_process											owl:Class	
GO:1905668	biolink:NamedThing	positive regulation of protein localization to endosome	Any process that activates or increases the frequency, rate or extent of protein localization to endosome.	tmpzr1t_l9r_go_relaxed.owl	up regulation of protein localization in endosome|positive regulation of protein localisation in endosome|upregulation of protein localisation in endosome|activation of protein localization to endosome|upregulation of protein localization to endosome|up regulation of protein localization to endosome|up regulation of protein localisation in endosome|activation of protein localisation in endosome|activation of protein localization in endosome|up-regulation of protein localisation in endosome|up-regulation of protein localization to endosome|up-regulation of protein localization in endosome|upregulation of protein localization in endosome|positive regulation of protein localization in endosome							bc	2016-11-11T11:19:17Z					biological_process											owl:Class	
GO:1905666	biolink:NamedThing	regulation of protein localization to endosome	Any process that modulates the frequency, rate or extent of protein localization to endosome.	tmpzr1t_l9r_go_relaxed.owl	regulation of protein localization in endosome|regulation of protein localisation in endosome							bc	2016-11-11T11:19:01Z					biological_process											owl:Class	
GO:1901404	biolink:NamedThing	regulation of tetrapyrrole catabolic process	Any process that modulates the frequency, rate or extent of tetrapyrrole catabolic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of tetrapyrrole catabolism|regulation of tetrapyrrole degradation|regulation of tetrapyrrole breakdown							tt	2012-10-01T14:38:12Z					biological_process											owl:Class	
GO:0039604	biolink:NamedThing	suppression by virus of host translation	Any process in which a virus prevents or reduces the frequency, rate or extent of translation of host mRNA.	tmpzr1t_l9r_go_relaxed.owl	viral inhibition of cellular protein synthesis|viral shutoff of host protein synthesis|host translation shutoff by virus				VZ:1579			bf	2012-07-05T04:25:22Z					biological_process											owl:Class	
GO:0019057	biolink:NamedThing	modulation by virus of host translation	Any process in which a virus modulates the frequency, rate or extent of translation of host mRNA.	tmpzr1t_l9r_go_relaxed.owl	host cell protein synthesis shutoff|regulation of translation in host by virus|regulation of host translation by virus|modification by virus of host cell mRNA translation|modulation of host translation by virus|viral host shutoff protein|viral perturbation of host cell mRNA translation|regulation of host mRNA translation by virus|host cell shutoff													biological_process											owl:Class	
GO:0010604	biolink:NamedThing	positive regulation of macromolecule metabolic process	Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0000702	biolink:NamedThing	oxidized base lesion DNA N-glycosylase activity	Catalysis of the removal of oxidized bases by cleaving the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar. The reaction releases a free base and leaves an apurinic/apyrimidinic (AP) site.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0019104	biolink:NamedThing	DNA N-glycosylase activity	Catalysis of the removal of damaged bases by cleaving the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar. The reaction releases a free base and leaves an apurinic/apyrimidinic (AP) site.	tmpzr1t_l9r_go_relaxed.owl	DNA glycosylase activity|endonuclease VIII activity				Reactome:R-HSA-5649673|Reactome:R-HSA-110251|Reactome:R-HSA-5649658|Reactome:R-HSA-9629216|Reactome:R-HSA-9635996|Reactome:R-HSA-110234|Reactome:R-HSA-5220959|Reactome:R-HSA-110246|Reactome:R-HSA-110250|Reactome:R-HSA-9629149|Reactome:R-HSA-9629499|Reactome:R-HSA-110231|Reactome:R-HSA-5221061|Reactome:R-HSA-9629483|Reactome:R-HSA-110218|Reactome:R-HSA-5649681|Reactome:R-HSA-9629470|Reactome:R-HSA-9636008|Reactome:R-HSA-110232|Reactome:R-HSA-5649664|Reactome:R-HSA-110219|Reactome:R-HSA-9629497|Reactome:R-HSA-110248|Reactome:R-HSA-9629492							GO:0008578		molecular_function											owl:Class	
GO:0007444	biolink:NamedThing	imaginal disc development	The process whose specific outcome is the progression of the imaginal disc over time, from its formation to the metamorphosis to form adult structures. Imaginal discs are epithelial infoldings in the larvae of holometabolous insects that develop into adult structures (legs, antennae, wings, etc.).	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1904138	biolink:NamedThing	positive regulation of convergent extension involved in notochord morphogenesis	Any process that activates or increases the frequency, rate or extent of convergent extension involved in notochord morphogenesis.	tmpzr1t_l9r_go_relaxed.owl	up regulation of convergent extension involved in notochord morphogenesis|upregulation of convergent extension involved in notochord morphogenesis|up-regulation of convergent extension involved in notochord morphogenesis|activation of convergent extension involved in notochord morphogenesis							dph	2015-04-10T21:21:41Z					biological_process											owl:Class	
GO:1904105	biolink:NamedThing	positive regulation of convergent extension involved in gastrulation	Any process that activates or increases the frequency, rate or extent of convergent extension involved in gastrulation.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of convergent extension involved in gastrulation|upregulation of convergent extension involved in gastrulation|up regulation of convergent extension involved in gastrulation|activation of convergent extension involved in gastrulation							dph	2015-04-01T11:17:18Z					biological_process											owl:Class	
GO:0051302	biolink:NamedThing	regulation of cell division	Any process that modulates the frequency, rate or extent of the physical partitioning and separation of a cell into daughter cells.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1990550	biolink:NamedThing	mitochondrial alpha-ketoglutarate transmembrane transport	The process in which alpha-ketoglutarate is transported across a mitochondrial membrane, into or out of the mitochondrion.	tmpzr1t_l9r_go_relaxed.owl	mitochondrial 2-oxoglutarate transmembrane transport							vw	2014-11-19T12:11:59Z			GO:1990552		biological_process											owl:Class	
GO:1901648	biolink:NamedThing	regulation of actomyosin contractile ring localization	Any process that modulates the frequency, rate or extent of actomyosin contractile ring localization.	tmpzr1t_l9r_go_relaxed.owl	regulation of contractile ring localization involved in cell cycle cytokinesis|regulation of contractile ring localisation involved in cell cycle cytokinesis							vw	2012-11-19T13:42:45Z					biological_process											owl:Class	
GO:0015881	biolink:NamedThing	creatine transmembrane transport	The directed movement of creatine across a membrane.	tmpzr1t_l9r_go_relaxed.owl	creatine transport							pr	2013-12-20T11:01:18Z			GO:1902598		biological_process											owl:Class	
GO:0060921	biolink:NamedThing	sinoatrial node cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a sinoatrial (SA) node cell. SA node cells are pacemaker cells that are found in the sinoatrial node.	tmpzr1t_l9r_go_relaxed.owl	SA node cell differentiation|sinus node cell differentiation|SAN cell differentiation							dph	2009-09-29T11:03:30Z					biological_process											owl:Class	
GO:0060920	biolink:NamedThing	cardiac pacemaker cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a pacemaker cell. Pacemaker cells are specialized cardiomyocytes that are responsible for regulating the timing of heart contractions.	tmpzr1t_l9r_go_relaxed.owl	pacemaker cell differentiation							dph	2009-09-29T11:01:31Z					biological_process											owl:Class	
GO:0030808	biolink:NamedThing	regulation of nucleotide biosynthetic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nucleotides.	tmpzr1t_l9r_go_relaxed.owl	regulation of nucleotide formation|regulation of nucleotide anabolism|regulation of nucleotide biosynthesis|regulation of nucleotide synthesis													biological_process											owl:Class	
GO:0015797	biolink:NamedThing	mannitol transport	The directed movement of mannitol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Mannitol is the alditol derived from D-mannose by reduction of the aldehyde group.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0015791	biolink:NamedThing	polyol transport	The directed movement of polyols, any polyhydric alcohol, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0060219	biolink:NamedThing	camera-type eye photoreceptor cell differentiation	The process in which a relatively unspecialized cell acquires the specialized features of a photoreceptor cell in a camera-type eye.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0001754	biolink:NamedThing	eye photoreceptor cell differentiation	The process in which a relatively unspecialized cell acquires the specialized features of a photoreceptor cell, as found in the eye, the primary visual organ of most organisms.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0002888	biolink:NamedThing	positive regulation of myeloid leukocyte mediated immunity	Any process that activates or increases the frequency, rate, or extent of myeloid leukocyte mediated immunity.	tmpzr1t_l9r_go_relaxed.owl	up regulation of myeloid leukocyte mediated immunity|up-regulation of myeloid leukocyte mediated immunity|upregulation of myeloid leukocyte mediated immunity|activation of myeloid leukocyte mediated immunity|stimulation of myeloid leukocyte mediated immunity													biological_process											owl:Class	
GO:2000706	biolink:NamedThing	negative regulation of dense core granule biogenesis	Any process that stops, prevents or reduces the frequency, rate or extent of dense core granule biogenesis.	tmpzr1t_l9r_go_relaxed.owl								yaf	2011-05-26T10:29:27Z					biological_process											owl:Class	
GO:0042854	biolink:NamedThing	eugenol metabolic process	The chemical reactions and pathways involving eugenol, a colorless, aromatic, liquid hydrocarbon (C10H12O2) found in clove oil.	tmpzr1t_l9r_go_relaxed.owl	eugenol metabolism|4-allyl-2-methoxyphenol metabolism|eugenic acid metabolic process|eugenic acid metabolism|4-allyl-2-methoxyphenol metabolic process													biological_process											owl:Class	
GO:1900735	biolink:NamedThing	positive regulation of flocculation	Any process that activates or increases the frequency, rate or extent of flocculation.	tmpzr1t_l9r_go_relaxed.owl	activation of flocculation via cell wall protein-carbohydrate interaction|upregulation of flocculation|up regulation of flocculation via cell wall protein-carbohydrate interaction|up-regulation of flocculation|upregulation of flocculation via cell wall protein-carbohydrate interaction|up-regulation of flocculation via cell wall protein-carbohydrate interaction|up regulation of flocculation|positive regulation of flocculation via cell wall protein-carbohydrate interaction|activation of flocculation							dgf	2012-05-27T08:27:38Z			GO:1900479		biological_process											owl:Class	
GO:0060256	biolink:NamedThing	regulation of flocculation	Any process that modulates the rate, frequency or extent of the non-sexual aggregation of single-celled organisms.	tmpzr1t_l9r_go_relaxed.owl	regulation of flocculation via cell wall protein-carbohydrate interaction							dgf	2012-05-01T05:03:32Z			GO:1900455		biological_process											owl:Class	
GO:0015119	biolink:NamedThing	hexose phosphate transmembrane transporter activity	Enables the transfer of hexose phosphate from one side of a membrane to the other. Hexose phosphates is any of a group of monophosphorylated aldoses with a chain of six carbon atoms in the molecule.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0001181	biolink:NamedThing	RNA polymerase I general transcription initiation factor activity	A general transcription initiation factor activity that contributes to transcription start site selection and transcription initiation of genes transcribed by RNA polymerase I. Factors required for RNA polymerase I transcription initiation include upstream activation factor (UAF), core factor (CF), TATA binding protein (TBP) and RRN3. In all species characterized, RNA polymerase I transcribes a large polycistronic transcript that is processed into several mature rRNAs (3 or 4 depending on the species), including the large subunit rRNA (28S in humans), the small subunit rRNA (18S in humans), as well as one or two additional smaller rRNAs (the 5.8S rRNA in humans). In most species, this large rRNA transcript is the sole product of RNA polymerase I. However there are rare exceptions, such as Trypanosoma brucei, where RNA polymerase I also transcribes certain mRNAs.	tmpzr1t_l9r_go_relaxed.owl	general RNA polymerase I transcription factor activity|RNA polymerase I transcription general initiation factor activity|transcription factor activity, core RNA polymerase I binding|core RNA polymerase I binding transcription factor activity	https://github.com/geneontology/go-ontology/issues/14736|https://github.com/geneontology/go-ontology/issues/20253						krc	2011-08-12T04:13:30Z					molecular_function											owl:Class	
GO:0140223	biolink:NamedThing	general transcription initiation factor activity	A molecular function required for core promoter activity that mediates the assembly of the RNA polymerase holoenzyme at promoter DNA to form the pre-initiation complex (PIC). General transcription factors (GTFs) bind to and open promoter DNA, initiate RNA synthesis and stimulate the escape of the polymerase from the promoter. Not all subunits of the general transcription factor are necessarily present at all promoters to initiate transcription. GTFs act at each promoter, although the exact subunit composition at individual promoters may vary.	tmpzr1t_l9r_go_relaxed.owl	general transcription factor activity|GTF activity|basal transcription factor activity	https://github.com/geneontology/go-ontology/issues/20253				Usage guidance: The distinction between general transcription factors and DNA-binding transcription factors is that the latter modulate the selection of which genes are expressed under specific conditions, while general transcription factors are the constitutive machinery required for transcription initiation.		pg	2018-05-24T07:51:23Z					molecular_function											owl:Class	
GO:0035029	biolink:NamedThing	dorsal closure, leading edge cell fate commitment	The commitment of cells to leading edge cell fate during dorsal closure. Leading edge cells are the dorsal-most cells of the migrating epidermis.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0035027	biolink:NamedThing	leading edge cell fate commitment	The commitment of cells to leading edge cell fate and their capacity to differentiate into leading edge cells. Leading edge cells are found at the front of a migrating epithelial sheet.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1990264	biolink:NamedThing	peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity	Any peptidyl-tyrosine dephosphorylation that is involved in inactivation of protein kinase activity.	tmpzr1t_l9r_go_relaxed.owl								al	2014-01-09T14:28:41Z					biological_process											owl:Class	
GO:0035335	biolink:NamedThing	peptidyl-tyrosine dephosphorylation	The removal of phosphoric residues from peptidyl-O-phospho-tyrosine to form peptidyl-tyrosine.	tmpzr1t_l9r_go_relaxed.owl								bf	2010-03-01T01:09:14Z					biological_process											owl:Class	
GO:2000344	biolink:NamedThing	positive regulation of acrosome reaction	Any process that activates or increases the frequency, rate or extent of the acrosome reaction.	tmpzr1t_l9r_go_relaxed.owl								yaf	2011-02-01T12:02:18Z					biological_process											owl:Class	
GO:0016613	biolink:NamedThing	vanadium-iron nitrogenase complex	An enzyme complex containing a vanadium-iron cluster found in some species, such as Azotobacter vinelandii. It is composed of two proteins, dinitrogenase and nitrogenase reductase; dinitrogenase, the vanadium-iron protein, is tetrameric with an alpha2-beta2 structure, and nitrogenase reductase is a homodimer.	tmpzr1t_l9r_go_relaxed.owl	vanadium-iron nitrogenase activity													cellular_component											owl:Class	
GO:0016610	biolink:NamedThing	nitrogenase complex	An enzyme complex composed of two proteins, dinitrogenase and nitrogenase reductase; dinitrogenase is tetrameric with an alpha2-beta2 structure and nitrogenase reductase is a homodimer, and both are associated with metal ions, which differ between species. Both proteins are required for the enzyme activity of the complex, the formation of oxidized ferredoxin and ammonia from reduced ferredoxin and nitrogen.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0015432	biolink:NamedThing	ABC-type bile acid transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: bile acid(in) + ATP + H2O -> bile acid(out) + ADP + phosphate.	tmpzr1t_l9r_go_relaxed.owl	ATP-dependent bile acid transmembrane transporter activity|bile acid-exporting ATPase activity|ATPase-coupled bile acid transmembrane transporter activity|bile acid porter activity				Reactome:R-HSA-193362|TC:3.A.1.207.2|RHEA:50048|Reactome:R-HSA-194153|Reactome:R-HSA-5678517									molecular_function											owl:Class	
GO:0015125	biolink:NamedThing	bile acid transmembrane transporter activity	Enables the transfer of bile acid from one side of a membrane to the other. Bile acids are any of a group of steroid carboxylic acids occurring in bile, where they are present as the sodium salts of their amides with glycine or taurine.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-194130|Reactome:R-HSA-5661184|Reactome:R-HSA-194083|Reactome:R-HSA-194079|Reactome:R-HSA-5661198									molecular_function											owl:Class	
GO:0018594	biolink:NamedThing	tert-butanol 2-monooxygenase activity	Catalysis of the reaction: tert-butanol + 1/2 O2 = 2-methyl-2-hydroxy-1-propanol.	tmpzr1t_l9r_go_relaxed.owl	tert-butyl alcohol 2-monooxygenase activity													molecular_function											owl:Class	
GO:0047628	biolink:NamedThing	ADP-thymidine kinase activity	Catalysis of the reaction: ADP + thymidine = AMP + thymidine 5'-phosphate.	tmpzr1t_l9r_go_relaxed.owl	ADP:thymidine 5'-phosphotransferase activity|ADP:dThd phosphotransferase activity|adenosine diphosphate-thymidine phosphotransferase activity				EC:2.7.1.118|RHEA:13413|MetaCyc:ADP--THYMIDINE-KINASE-RXN									molecular_function											owl:Class	
GO:0052072	biolink:NamedThing	induction by symbiont of defense-related host salicylic acid-mediated signal transduction pathway	Any process in which a symbiont activates, maintains or increases the frequency, rate or extent of host salicylic acid-mediated signal transduction pathways during the host defense response. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	activation by organism of defense-related host salicylic acid-mediated signal transduction pathway|activation by organism of defense-related host SA-mediated signal transduction pathway|upregulation by organism of defense-related host SA-mediated signal transduction pathway|upregulation by organism of defense-related host salicylic acid-mediated signal transduction pathway|induction by organism of defense-related host SA-mediated signal transduction pathway|positive regulation by organism of defense-related host SA-mediated signal transduction pathway|up regulation by symbiont of defense-related host salicylic acid-mediated signal transduction pathway|positive regulation by organism of defense-related salicylic acid-mediated signal transduction pathway in other organism involved in symbiotic interaction|upregulation by symbiont of defense-related host salicylic acid-mediated signal transduction pathway|positive regulation by symbiont of defense-related host salicylic acid-mediated signal transduction pathway|induction by organism of defense-related host salicylic acid-mediated signal transduction pathway|up-regulation by symbiont of defense-related host salicylic acid-mediated signal transduction pathway|activation by symbiont of defense-related host salicylic acid-mediated signal transduction pathway|stimulation by symbiont of defense-related host salicylic acid-mediated signal transduction pathway											GO:0052270		biological_process											owl:Class	
GO:0052081	biolink:NamedThing	modulation by symbiont of defense-related host salicylic acid-mediated signal transduction pathway	Any process in which an organism modulates the frequency, rate or extent of host salicylic acid-mediated signal transduction pathways during the host defense response. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	modulation by organism of defense-related salicylic acid-mediated signal transduction pathway in other organism involved in symbiotic interaction|modulation of defense-related host SA-mediated signal transduction pathway by organism											GO:0052445		biological_process											owl:Class	
GO:0014747	biolink:NamedThing	positive regulation of tonic skeletal muscle contraction	Any process that activates or increases the frequency, rate or extent of tonic skeletal muscle contraction.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0031475	biolink:NamedThing	myosin V complex	A myosin complex containing a dimer of class V myosin heavy chains and associated light chains; involved in intracellular transport. Myosin V is a dimeric molecule consisting of conserved motor domains followed by 6 IQ motifs which bind specific light chains and calmodulin. The tail domain is important for cellular localization and cargo binding and can be divided into an alpha-helical coiled coil region and a C-terminal globular region.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0016461	biolink:NamedThing	unconventional myosin complex	A portmanteau term for myosins other than myosin II.	tmpzr1t_l9r_go_relaxed.owl	non-muscle myosin					Note that this term is retained because it is widely used by biologists.						GO:0005860		cellular_component											owl:Class	
GO:0031925	biolink:NamedThing	pyridoxal transmembrane transporter activity	Enables the transfer of pyridoxal from one side of a membrane to the other. Pyridoxal, 3-hydroxy-5-(hydroxymethyl)-2-methyl-4-pyridinecarboxaldehyde, is one of the vitamin B6 compounds. Pyridoxal, pyridoxamine and pyridoxine are collectively known as vitamin B6, and are efficiently converted to the biologically active form of vitamin B6, pyridoxal phosphate.	tmpzr1t_l9r_go_relaxed.owl	pyridoxal transporter activity													molecular_function											owl:Class	
GO:0014043	biolink:NamedThing	negative regulation of neuron maturation	Any process that stops, prevents, or reduces the frequency, rate or extent of neuron maturation.	tmpzr1t_l9r_go_relaxed.owl	inhibition of neuron maturation|downregulation of neuron maturation|down-regulation of neuron maturation|down regulation of neuron maturation													biological_process											owl:Class	
GO:1903430	biolink:NamedThing	negative regulation of cell maturation	Any process that stops, prevents or reduces the frequency, rate or extent of cell maturation.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of functional differentiation|down-regulation of functional differentiation|downregulation of cell maturation|inhibition of functional differentiation|inhibition of cell maturation|down regulation of cell maturation|down regulation of functional differentiation|down-regulation of cell maturation|downregulation of functional differentiation							jl	2014-09-15T13:31:32Z					biological_process											owl:Class	
GO:0099630	biolink:NamedThing	postsynaptic neurotransmitter receptor cycle	The process during which neurotransmitter receptors in the postsynaptic specialization membrane are recycled via the endosome. This cycle includes release from anchoring (trapping), diffusion in the synaptic membrane to the postsynaptic endocytic region, endocytosis, transport to the endosome, recycling in the endosome,  transport back the synaptic membrane and subsequent trapping in the postsynaptic specialization membrane.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0099627	biolink:NamedThing	neurotransmitter receptor cycle	The process during which neurotransmitter receptors, anchored in some region of the synaptic membrane, are recycled via the endosome.  This cycle includes release from anchoring, diffusion in the synaptic membrane to an endocytic region, endocytosis, transport to the endosome, recycling in the endosome,  transport back the synaptic membrane and subsequent anchoring (trapping).	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0047255	biolink:NamedThing	galactogen 6-beta-galactosyltransferase activity	Catalysis of the reaction: galactogen + UDP-galactose = 1,6-beta-D-galctosylgalactogen + UDP.	tmpzr1t_l9r_go_relaxed.owl	1,6-D-galactosyltransferase activity|uridine diphosphogalactose-galactogen galactosyltransferase activity|UDPgalactose:galactogen beta-1,6-D-galactosyltransferase activity|UDP-galactose:galactogen beta-1,6-D-galactosyltransferase activity|galactogen 6beta-galactosyltransferase activity|beta-(1,6)-D-galactosyltransferase activity				MetaCyc:2.4.1.205-RXN|EC:2.4.1.205									molecular_function											owl:Class	
GO:0035250	biolink:NamedThing	UDP-galactosyltransferase activity	Catalysis of the transfer of a galactose group from UDP-galactose to an acceptor molecule.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0042326	biolink:NamedThing	negative regulation of phosphorylation	Any process that stops, prevents or decreases the rate of addition of phosphate groups to a molecule.	tmpzr1t_l9r_go_relaxed.owl	down regulation of phosphorylation|down-regulation of phosphorylation|inhibition of phosphorylation|downregulation of phosphorylation													biological_process											owl:Class	
GO:1903335	biolink:NamedThing	regulation of vacuolar transport	Any process that modulates the frequency, rate or extent of vacuolar transport.	tmpzr1t_l9r_go_relaxed.owl								vw	2014-08-18T13:16:04Z					biological_process											owl:Class	
GO:0035115	biolink:NamedThing	embryonic forelimb morphogenesis	The process, occurring in the embryo, by which the anatomical structures of the forelimb are generated and organized. The forelimbs are the front limbs of an animal, e.g. the arms of a human.	tmpzr1t_l9r_go_relaxed.owl	embryonic arm morphogenesis											GO:0035117		biological_process											owl:Class	
GO:0030326	biolink:NamedThing	embryonic limb morphogenesis	The process, occurring in the embryo, by which the anatomical structures of the limb are generated and organized. A limb is an appendage of an animal used for locomotion or grasping.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0048329	biolink:NamedThing	negative regulation of axial mesodermal cell fate specification	Any process that stops, prevents, or reduces the frequency, rate or extent of axial mesoderm cell fate specification.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of axial mesodermal cell fate specification|downregulation of axial mesodermal cell fate specification|down regulation of axial mesodermal cell fate specification|inhibition of axial mesodermal cell fate specification													biological_process											owl:Class	
GO:0048328	biolink:NamedThing	regulation of axial mesodermal cell fate specification	Any process that modulates the frequency, rate or extent of axial mesoderm cell fate specification.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0090096	biolink:NamedThing	positive regulation of metanephric cap mesenchymal cell proliferation	Any process that increases the frequency, rate, or extent of metanephric cap mesenchymal cell proliferation. Metanephric cap mesenchymal cell proliferation is the multiplication or reproduction of metanephric cap mesenchymal cells, resulting in the expansion of the cell population. A metanephric cap mesenchymal cell is a mesenchymal cell that has condensed with other mesenchymal cells surrounding the ureteric bud tip.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-11-13T10:40:32Z					biological_process											owl:Class	
GO:0002053	biolink:NamedThing	positive regulation of mesenchymal cell proliferation	The process of activating or increasing the rate or extent of mesenchymal cell proliferation. Mesenchymal cells are loosely organized embryonic cells.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of mesenchymal cell proliferation|activation of mesenchymal cell proliferation|up regulation of mesenchymal cell proliferation|upregulation of mesenchymal cell proliferation|stimulation of mesenchymal cell proliferation													biological_process											owl:Class	
GO:0080178	biolink:NamedThing	5-carbamoylmethyl uridine residue modification	The chemical reactions and pathways involving the addition of a  5-carbamoylmethyl group to a uridine residue in RNA.	tmpzr1t_l9r_go_relaxed.owl	5-carbamoylmethyluridine metabolic process							dhl	2011-04-28T04:36:23Z					biological_process											owl:Class	
GO:0030488	biolink:NamedThing	tRNA methylation	The posttranscriptional addition of methyl groups to specific residues in a tRNA molecule.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0048794	biolink:NamedThing	swim bladder development	The process whose specific outcome is the progression of the swim bladder over time, from its formation to the mature structure. The swim bladder is used by some fishes to maintain buoyancy and may function in addition as a sound producing organ, a sound receptor, and a respiratory organ.	tmpzr1t_l9r_go_relaxed.owl	gas bladder development													biological_process											owl:Class	
GO:1905201	biolink:NamedThing	gibberellin transmembrane transporter activity	Enables the transfer of gibberellin from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl								lr	2016-05-12T18:20:13Z					molecular_function											owl:Class	
GO:0051085	biolink:NamedThing	chaperone cofactor-dependent protein refolding	The process of assisting in the correct posttranslational noncovalent assembly of proteins, which is dependent on additional protein cofactors. This process occurs over one or several cycles of nucleotide hydrolysis-dependent binding and release.	tmpzr1t_l9r_go_relaxed.owl	chaperone cofactor-dependent 'de novo' protein folding|chaperone mediated protein folding requiring cofactor|chaperone cofactor-dependent protein folding|chaperone co-factor-dependent protein folding|chaperone co-factor-dependent protein refolding	https://github.com/geneontology/go-ontology/issues/10726										GO:0070389		biological_process											owl:Class	
GO:1905236	biolink:NamedThing	cellular response to quercetin	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a quercetin stimulus.	tmpzr1t_l9r_go_relaxed.owl								sl	2016-06-07T21:29:48Z					biological_process											owl:Class	
GO:1905235	biolink:NamedThing	response to quercetin	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a quercetin stimulus.	tmpzr1t_l9r_go_relaxed.owl								sl	2016-06-07T21:29:40Z					biological_process											owl:Class	
GO:0018253	biolink:NamedThing	peptide cross-linking via 5-imidazolinone glycine	The formation of a protein active site cross-link from the alpha-carboxyl carbon of residue n, an alanine, serine or cysteine, to the alpha-amino nitrogen of residue n+2, a glycine, and a dehydration to form a double bond to the alpha-amino nitrogen of residue n+1. This cross-linking is coupled with an oxidation of residue n+1 to form an active aldehyde.	tmpzr1t_l9r_go_relaxed.owl	biosynthesis of protein-protein cross-link via 5-imidazolinone glycine|biosynthetic process of protein-protein cross-link via 5-imidazolinone glycine				RESID:AA0184|RESID:AA0187|RESID:AA0188									biological_process											owl:Class	
GO:0018149	biolink:NamedThing	peptide cross-linking	The formation of a covalent cross-link between or within protein chains.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:2000495	biolink:NamedThing	regulation of cell proliferation involved in compound eye morphogenesis	Any process that modulates the frequency, rate or extent of cell proliferation involved in compound eye morphogenesis.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-03-18T02:18:34Z					biological_process											owl:Class	
GO:1903058	biolink:NamedThing	positive regulation of melanosome organization	Any process that activates or increases the frequency, rate or extent of melanosome organization.	tmpzr1t_l9r_go_relaxed.owl	up regulation of melanosome organization and biogenesis|activation of melanosome organization and biogenesis|upregulation of melanosome organization|positive regulation of melanosome organization and biogenesis|up regulation of melanosome organization|positive regulation of melanosome organisation|up-regulation of melanosome organization|up-regulation of melanosome organisation|up regulation of melanosome organisation|upregulation of melanosome organization and biogenesis|activation of melanosome organisation|activation of melanosome organization|up-regulation of melanosome organization and biogenesis|upregulation of melanosome organisation					Lack of the transcription factor Zeb2 Q9R0G7 leads to spherical melanosomes with irregular borders, in contrast to the rod-shaped melanosomes of ZEB2MCWT hair follicles.		rl	2014-05-27T13:28:01Z					biological_process											owl:Class	
GO:0010638	biolink:NamedThing	positive regulation of organelle organization	Any process that increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of organelle organization and biogenesis|positive regulation of organelle organisation													biological_process											owl:Class	
GO:1900901	biolink:NamedThing	positive regulation of heptadecane metabolic process	Any process that activates or increases the frequency, rate or extent of heptadecane metabolic process.	tmpzr1t_l9r_go_relaxed.owl	upregulation of heptadecane metabolism|up regulation of heptadecane metabolic process|up-regulation of heptadecane metabolism|upregulation of heptadecane metabolic process|positive regulation of heptadecane metabolism|up-regulation of heptadecane metabolic process|activation of heptadecane metabolism|activation of heptadecane metabolic process|up regulation of heptadecane metabolism							tt	2012-06-13T03:30:33Z					biological_process											owl:Class	
GO:0150202	biolink:NamedThing	negative regulation of transport across blood-brain barrier	Any process that stops, prevents or reduces the frequency, rate or extent of transport across blood-brain barrier.	tmpzr1t_l9r_go_relaxed.owl								bc	2020-03-26T19:28:51Z					biological_process											owl:Class	
GO:0052581	biolink:NamedThing	(-)-isopiperitenone reductase activity	Catalysis of the reaction: (6R)-isoperitenone + H(+) + NADPH = (2R,5R)-isopulegone + NADP(+).	tmpzr1t_l9r_go_relaxed.owl	(+)-cis-isopulegone:NADP+ oxidoreductase activity				MetaCyc:RXN-5161|KEGG_REACTION:R06417|RHEA:25649|EC:1.3.1.82			ai	2010-08-09T04:42:05Z					molecular_function											owl:Class	
GO:0035671	biolink:NamedThing	enone reductase activity	Catalysis of the reaction: an enone + NADPH + H+ = a ketone + NADP+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-12267			bf	2011-02-04T10:59:15Z					molecular_function											owl:Class	
GO:1903322	biolink:NamedThing	positive regulation of protein modification by small protein conjugation or removal	Any process that activates or increases the frequency, rate or extent of protein modification by small protein conjugation or removal.	tmpzr1t_l9r_go_relaxed.owl	upregulation of protein modification by small protein conjugation or removal|activation of protein modification by small protein conjugation or removal|up-regulation of protein modification by small protein conjugation or removal|up regulation of protein modification by small protein conjugation or removal							vw	2014-08-18T13:01:15Z					biological_process											owl:Class	
GO:1903320	biolink:NamedThing	regulation of protein modification by small protein conjugation or removal	Any process that modulates the frequency, rate or extent of protein modification by small protein conjugation or removal.	tmpzr1t_l9r_go_relaxed.owl								vw	2014-08-18T13:01:00Z					biological_process											owl:Class	
GO:0036487	biolink:NamedThing	nitric-oxide synthase inhibitor activity	Binds to and stops, prevents or reduces the activity of nitric oxide synthase.	tmpzr1t_l9r_go_relaxed.owl	nitric oxide synthase inhibitor activity|NOS inhibitor activity							bf	2014-09-09T15:07:20Z					molecular_function											owl:Class	
GO:0030235	biolink:NamedThing	nitric-oxide synthase regulator activity	Binds to and modulates the activity of nitric oxide synthase.	tmpzr1t_l9r_go_relaxed.owl	nitric oxide synthase regulator activity					See also 'regulation of nitric-oxide synthase activity ; GO:0050999'.								molecular_function											owl:Class	
GO:1905758	biolink:NamedThing	positive regulation of primary cell septum biogenesis	Any process that activates or increases the frequency, rate or extent of primary cell septum biogenesis.	tmpzr1t_l9r_go_relaxed.owl								vw	2016-12-12T18:10:07Z					biological_process											owl:Class	
GO:1905756	biolink:NamedThing	regulation of primary cell septum biogenesis	Any process that modulates the frequency, rate or extent of primary cell septum biogenesis.	tmpzr1t_l9r_go_relaxed.owl								vw	2016-12-12T18:09:50Z					biological_process											owl:Class	
GO:1904510	biolink:NamedThing	positive regulation of protein localization to basolateral plasma membrane	Any process that activates or increases the frequency, rate or extent of protein localization to basolateral plasma membrane.	tmpzr1t_l9r_go_relaxed.owl	upregulation of protein localisation to basolateral plasma membrane|up-regulation of protein localisation in basolateral plasma membrane|up regulation of protein localization in basolateral plasma membrane|up regulation of protein localisation in basolateral plasma membrane|up-regulation of protein localization in basolateral plasma membrane|up-regulation of protein localisation to basolateral plasma membrane|up-regulation of protein localization to basolateral plasma membrane|upregulation of protein localisation in basolateral plasma membrane|positive regulation of protein localization in basolateral plasma membrane|up regulation of protein localization to basolateral plasma membrane|upregulation of protein localization in basolateral plasma membrane|upregulation of protein localization to basolateral plasma membrane|up regulation of protein localisation to basolateral plasma membrane|activation of protein localization to basolateral plasma membrane|positive regulation of protein localisation to basolateral plasma membrane|activation of protein localization in basolateral plasma membrane|positive regulation of protein localisation in basolateral plasma membrane|activation of protein localisation to basolateral plasma membrane|activation of protein localisation in basolateral plasma membrane							kmv	2015-07-24T17:56:38Z					biological_process											owl:Class	
GO:0043020	biolink:NamedThing	NADPH oxidase complex	A enzyme complex of which the core is a heterodimer composed of a light (alpha) and heavy (beta) chain, and requires several other water-soluble proteins of cytosolic origin for activity. Functions in superoxide generation by the NADPH-dependent reduction of O2.	tmpzr1t_l9r_go_relaxed.owl	flavocytochrome b558|respiratory-burst oxidase													cellular_component											owl:Class	
GO:0015677	biolink:NamedThing	copper ion import	The directed movement of copper ions into a cell or organelle.	tmpzr1t_l9r_go_relaxed.owl	copper ion uptake													biological_process											owl:Class	
GO:0006825	biolink:NamedThing	copper ion transport	The directed movement of copper (Cu) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0090293	biolink:NamedThing	nitrogen catabolite regulation of transcription	A transcription regulation process in which the presence of one nitrogen source leads to the modulation of the frequency, rate, or extent of transcription of specific genes involved in the metabolism of other nitrogen sources.	tmpzr1t_l9r_go_relaxed.owl	regulation of transcription by nitrogen catabolites							tb	2010-02-24T02:31:53Z					biological_process											owl:Class	
GO:1900236	biolink:NamedThing	positive regulation of Kit signaling pathway	Any process that activates or increases the frequency, rate or extent of Kit signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	activation of stem cell factor receptor signaling pathway|up regulation of stem cell factor receptor signaling pathway|up-regulation of stem cell factor receptor signaling pathway|upregulation of Kit signaling pathway|upregulation of stem cell factor receptor signaling pathway|positive regulation of stem cell factor receptor signaling pathway|up-regulation of Kit signaling pathway|up regulation of Kit signaling pathway|positive regulation of Kit signalling pathway|upregulation of stem cell factor signaling pathway|up regulation of stem cell factor signaling pathway|activation of stem cell factor signaling pathway|positive regulation of stem cell factor signaling pathway|up-regulation of stem cell factor signaling pathway|activation of Kit signaling pathway							bf	2012-03-23T02:54:32Z					biological_process											owl:Class	
GO:0031671	biolink:NamedThing	primary cell septum biogenesis	A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a primary cell septum following nuclear division.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1902410	biolink:NamedThing	mitotic cytokinetic process	Any cytokinetic process that is involved in mitotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl								jl	2013-09-12T12:29:36Z					biological_process											owl:Class	
GO:0005656	biolink:NamedThing	nuclear pre-replicative complex	A protein-DNA complex assembled at eukaryotic DNA replication origins during late mitosis and G1, allowing the origin to become competent, or 'licensed', for replication. The complex normally includes the origin recognition complex (ORC), Cdc6, Cdt1 and the MiniChromosome Maintenance (Mcm2-7) proteins.	tmpzr1t_l9r_go_relaxed.owl	pre-RC|eukaryotic pre-replicative complex|pre-replicative complex													cellular_component											owl:Class	
GO:0060898	biolink:NamedThing	eye field cell fate commitment involved in camera-type eye formation	The commitment of neurectodermal cells to cells of the eye field and their capacity to differentiate into eye field cells. Eye field cells are neurectodermal cells that will form the optic placode.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-08-13T02:10:58Z					biological_process											owl:Class	
GO:0060581	biolink:NamedThing	cell fate commitment involved in pattern specification	The commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells within a field of cells that will exhibit a certain pattern of differentiation. Positional information is established through protein signals that emanate from a localized source within a developmental field resulting in specification of a cell type. Those signals are then interpreted in a cell-autonomous manner resulting in the determination of the cell type.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-05-07T12:40:55Z					biological_process											owl:Class	
GO:0034952	biolink:NamedThing	malonate semialdehyde decarboxylase activity	Catalysis of the reaction: malonate semialdehyde + H+ = acetaldehyde + CO2.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0266									molecular_function											owl:Class	
GO:0046379	biolink:NamedThing	extracellular polysaccharide metabolic process	The chemical reactions and pathways involving polysaccharides used in extracellular structures.	tmpzr1t_l9r_go_relaxed.owl	extracellular polysaccharide metabolism													biological_process											owl:Class	
GO:0009971	biolink:NamedThing	anastral spindle assembly involved in male meiosis	The aggregation, arrangement and bonding together of a set of components to form the anastral spindle in male meiotic cells.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0015379	biolink:NamedThing	potassium:chloride symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: K+(out) + Cl-(out) = K+(in) + Cl-(in).	tmpzr1t_l9r_go_relaxed.owl	potassium ion symporter activity				Reactome:R-HSA-5623806|Reactome:R-HSA-426155							GO:0022820		molecular_function											owl:Class	
GO:0015377	biolink:NamedThing	cation:chloride symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: cation(out) + Cl-(out) = cation(in) + Cl-(in).	tmpzr1t_l9r_go_relaxed.owl	cation:chloride cotransporter activity													molecular_function											owl:Class	
GO:0036491	biolink:NamedThing	regulation of translation initiation in response to endoplasmic reticulum stress	Any process that modulates the frequency, rate or extent of translation initiation, as a result of endoplasmic reticulum stress.	tmpzr1t_l9r_go_relaxed.owl	regulation of translation initiation in response to ER stress							bf	2015-02-05T09:52:13Z					biological_process											owl:Class	
GO:0102533	biolink:NamedThing	genkwanin 4'-O-methyltransferase activity	Catalysis of the reaction: genkwanin + S-adenosyl-L-methionine  <=> H+ + apigenin-7,4'-dimethyl ether + S-adenosyl-L-homocysteine.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-14750									molecular_function											owl:Class	
GO:0098721	biolink:NamedThing	uracil import across plasma membrane	The directed movement of uracil from outside of a cell, across the plasma membrane and into the cytosol.	tmpzr1t_l9r_go_relaxed.owl	uracil import into cell							tb	2013-09-27T17:54:23Z			GO:1902431		biological_process											owl:Class	
GO:0098657	biolink:NamedThing	import into cell	The directed movement of some substance from outside of a cell into a cell. This may occur via transport across the plasma membrane or via endocytosis.	tmpzr1t_l9r_go_relaxed.owl	uptake													biological_process											owl:Class	
GO:0005092	biolink:NamedThing	GDP-dissociation inhibitor activity	Prevents the dissociation of GDP from a GTPase, thereby preventing GTP from binding.	tmpzr1t_l9r_go_relaxed.owl	GDI													molecular_function											owl:Class	
GO:0030695	biolink:NamedThing	GTPase regulator activity	Binds to and modulates the activity of a GTPase.	tmpzr1t_l9r_go_relaxed.owl	small GTPase regulatory/interacting protein activity|small GTPase regulator activity											GO:0005083		molecular_function											owl:Class	
GO:0098978	biolink:NamedThing	glutamatergic synapse	A synapse that uses glutamate as a neurotransmitter.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0045202	biolink:NamedThing	synapse	The junction between an axon of one neuron and a dendrite of another neuron, a muscle fiber or a glial cell. As the axon approaches the synapse it enlarges into a specialized structure, the presynaptic terminal bouton, which contains mitochondria and synaptic vesicles. At the tip of the terminal bouton is the presynaptic membrane; facing it, and separated from it by a minute cleft (the synaptic cleft) is a specialized area of membrane on the receiving cell, known as the postsynaptic membrane. In response to the arrival of nerve impulses, the presynaptic terminal bouton secretes molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane.	tmpzr1t_l9r_go_relaxed.owl	synaptic junction|electrotonic synapse|mixed synapse				Wikipedia:Chemical_synapse|NIF_Subcellular:sao914572699									cellular_component											owl:Class	
GO:0086011	biolink:NamedThing	membrane repolarization during action potential	The process in which ions are transported across a membrane such that the membrane potential changes in the direction from the positive membrane potential at the peak of the action potential towards the negative resting potential.	tmpzr1t_l9r_go_relaxed.owl								tb	2011-11-10T08:15:05Z					biological_process											owl:Class	
GO:1902623	biolink:NamedThing	negative regulation of neutrophil migration	Any process that stops, prevents or reduces the frequency, rate or extent of neutrophil migration.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of neutrophil migration|downregulation of neutrophil migration|down regulation of neutrophil migration|inhibition of neutrophil migration							sl	2014-01-15T18:58:49Z					biological_process											owl:Class	
GO:1900809	biolink:NamedThing	fumigaclavine C biosynthetic process	The chemical reactions and pathways resulting in the formation of fumigaclavine C.	tmpzr1t_l9r_go_relaxed.owl	fumigaclavine C biosynthesis|fumigaclavine C formation|fumigaclavine C anabolism|fumigaclavine C synthesis							di	2012-06-04T10:00:06Z					biological_process											owl:Class	
GO:0035837	biolink:NamedThing	ergot alkaloid biosynthetic process	The chemical reactions and pathways resulting in the formation of an ergot alkaloid.	tmpzr1t_l9r_go_relaxed.owl	ergot alkaloid formation|ergot alkaloid biosynthesis|ergot alkaloid anabolism|ergot alkaloid synthesis							bf	2011-05-04T03:23:57Z					biological_process											owl:Class	
GO:2000804	biolink:NamedThing	regulation of termination of RNA polymerase II transcription, poly(A)-coupled	Any process that modulates the frequency, rate or extent of termination of RNA polymerase II transcription, poly(A)-coupled.	tmpzr1t_l9r_go_relaxed.owl	regulation of transcription termination from Pol II promoter, RNA polymerase(A) coupled|regulation of transcription termination from Pol II promoter, poly(A) coupled|regulation of termination of RNA polymerase II transcription, polyadenylation-coupled							pr	2011-07-04T08:41:27Z					biological_process											owl:Class	
GO:1903202	biolink:NamedThing	negative regulation of oxidative stress-induced cell death	Any process that stops, prevents or reduces the frequency, rate or extent of oxidative stress-induced cell death.	tmpzr1t_l9r_go_relaxed.owl	inhibition of cell death in response to oxidative stress|down regulation of cell death in response to oxidative stress|protection against oxidative stress-induced cell death|downregulation of cell death in response to oxidative stress|negative regulation of cell death in response to oxidative stress|down-regulation of cell death in response to oxidative stress							bf	2014-07-21T16:10:36Z					biological_process											owl:Class	
GO:0032662	biolink:NamedThing	regulation of interleukin-19 production	Any process that modulates the frequency, rate, or extent of interleukin-19 production.	tmpzr1t_l9r_go_relaxed.owl	regulation of interleukin-19 biosynthetic process|regulation of IL-19 production											GO:0045384		biological_process											owl:Class	
GO:0008527	biolink:NamedThing	taste receptor activity	Combining with soluble compounds to initiate a change in cell activity. These receptors are responsible for the sense of taste.	tmpzr1t_l9r_go_relaxed.owl	gustatory receptor													molecular_function											owl:Class	
GO:0097190	biolink:NamedThing	apoptotic signaling pathway	A series of molecular signals which triggers the apoptotic death of a cell. The pathway starts with reception of a signal, and ends when the execution phase of apoptosis is triggered.	tmpzr1t_l9r_go_relaxed.owl	apoptotic signalling pathway|induction of apoptosis by extracellular signals					This term can be used to annotate gene products involved in apoptotic events happening downstream of the cross-talk point between the extrinsic and intrinsic apoptotic pathways. The cross-talk starts when caspase-8 cleaves Bid and truncated Bid interacts with mitochondria. From this point on it is not possible to distinguish between extrinsic and intrinsic pathways.		pr	2011-11-23T09:30:23Z			GO:0008624		biological_process											owl:Class	
GO:0022617	biolink:NamedThing	extracellular matrix disassembly	A process that results in the breakdown of the extracellular matrix.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0022411	biolink:NamedThing	cellular component disassembly	A cellular process that results in the breakdown of a cellular component.	tmpzr1t_l9r_go_relaxed.owl	cell structure disassembly|cellular component disassembly at cellular level											GO:0071845		biological_process											owl:Class	
GO:0038012	biolink:NamedThing	negative regulation of Wnt signaling pathway by Wnt receptor internalization	Any process in which internalization of a Wnt receptor stops, prevents, or reduces the frequency, rate or extent of Wnt signal transduction.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of Wnt receptor signalling pathway by Wnt receptor internalization|negative regulation of Wnt-activated signaling pathway by Wnt receptor internalization|ligand-dependent internalization of Frizzled|negative regulation of Wnt receptor signaling pathway by Wnt receptor internalization|negative regulation of Wnt receptor signaling pathway by Wnt receptor endocytosis							bf	2011-06-23T03:57:59Z					biological_process											owl:Class	
GO:0038011	biolink:NamedThing	negative regulation of signal transduction by receptor internalization	Any process in which internalization of a signaling receptor stops, prevents, or reduces the frequency, rate or extent of signal transduction. Receptor internalization can attenuate or reduce the strength of signaling by reducing the concentration of cell surface receptors available to ligands.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of signaling pathway by receptor endocytosis							bf	2011-06-23T03:39:06Z					biological_process											owl:Class	
GO:0044522	biolink:NamedThing	envenomation resulting in myocyte killing in other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, killing heart myocytes and ultimately resulting in muscle damage in the bitten organism.	tmpzr1t_l9r_go_relaxed.owl	envenomation resulting in myocyte killing causing muscle damage in other organism							jl	2012-02-27T12:33:57Z					biological_process											owl:Class	
GO:0044521	biolink:NamedThing	envenomation resulting in muscle damage in other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with resultant muscle damage in the bitten organism.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-02-27T12:31:08Z					biological_process											owl:Class	
GO:0090316	biolink:NamedThing	positive regulation of intracellular protein transport	Any process that activates or increases the frequency, rate or extent of the directed movement of proteins within cells.	tmpzr1t_l9r_go_relaxed.owl								tb	2010-04-16T03:45:07Z					biological_process											owl:Class	
GO:2000707	biolink:NamedThing	positive regulation of dense core granule biogenesis	Any process that activates or increases the frequency, rate or extent of dense core granule biogenesis.	tmpzr1t_l9r_go_relaxed.owl								yaf	2011-05-26T10:29:30Z					biological_process											owl:Class	
GO:2000705	biolink:NamedThing	regulation of dense core granule biogenesis	Any process that modulates the frequency, rate or extent of dense core granule biogenesis.	tmpzr1t_l9r_go_relaxed.owl								yaf	2011-05-26T10:29:21Z					biological_process											owl:Class	
GO:0048763	biolink:NamedThing	calcium-induced calcium release activity	Enables transmembrane transfer of calcium ions from an intracellular store to the cytosol on induction by increased calcium concentration.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0015278	biolink:NamedThing	calcium-release channel activity	Enables the transmembrane transfer of a calcium ion from intracellular stores by a channel that opens when a specific intracellular ligand has been bound by the channel complex or one of its constituent parts.	tmpzr1t_l9r_go_relaxed.owl	intracellular ligand-gated calcium channel activity											GO:0005218		molecular_function											owl:Class	
GO:1902180	biolink:NamedThing	verruculogen catabolic process	The chemical reactions and pathways resulting in the breakdown of verruculogen.	tmpzr1t_l9r_go_relaxed.owl	verruculogen breakdown|verruculogen degradation|verruculogen catabolism							di	2013-05-30T17:44:30Z					biological_process											owl:Class	
GO:0030214	biolink:NamedThing	hyaluronan catabolic process	The chemical reactions and pathways resulting in the breakdown of hyaluronan, the naturally occurring anionic form of hyaluronic acid, any member of a group of glycosaminoglycans, the repeat units of which consist of beta-1,4 linked D-glucuronyl-beta-(1,3)-N-acetyl-D-glucosamine.	tmpzr1t_l9r_go_relaxed.owl	hyaluronan degradation|hyaluronan catabolism|hyaluronan breakdown													biological_process											owl:Class	
GO:0006027	biolink:NamedThing	glycosaminoglycan catabolic process	The chemical reactions and pathways resulting in the breakdown of glycosaminoglycans, any one of a group of polysaccharides that contain amino sugars.	tmpzr1t_l9r_go_relaxed.owl	glycosaminoglycan catabolism|glycosaminoglycan degradation|glycosaminoglycan breakdown													biological_process											owl:Class	
GO:0160003	biolink:NamedThing	mono-ADP-D-ribose modification-dependent protein binding	Binding to a protein upon mono-ADP-ribosylation of the target protein.	tmpzr1t_l9r_go_relaxed.owl						This term should only be used when the binding is shown to require a mono-ADP-D-ribose post-translational modification: the interaction needs to be tested with and without the PTM. The binding does not need to be at the site of the ADP-D-ribose modification. It may be that the PTM causes a conformational change that allows binding of the protein to another region; this type of modification-dependent protein binding is valid for annotation to this term.		rl	2021-07-12T23:36:00Z					molecular_function											owl:Class	
GO:0160002	biolink:NamedThing	ADP-D-ribose modification-dependent protein binding	Binding to a protein upon ADP-ribosylation of the target protein.	tmpzr1t_l9r_go_relaxed.owl						This term should only be used when the binding is shown to require a ADP-D-ribose post-translational modification: the interaction needs to be tested with and without the PTM. The binding does not need to be at the site of the ADP-D-ribose modification. It may be that the PTM causes a conformational change that allows binding of the protein to another region; this type of modification-dependent protein binding is valid for annotation to this term.		rl	2021-07-12T23:31:53Z					molecular_function											owl:Class	
GO:0035163	biolink:NamedThing	embryonic hemocyte differentiation	The process in which a relatively unspecialized cell derived from the embryonic head mesoderm acquires the specialized features of a mature hemocyte. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen.	tmpzr1t_l9r_go_relaxed.owl	embryonic hemocyte cell differentiation|embryonic arthropod blood cell differentiation													biological_process											owl:Class	
GO:0042386	biolink:NamedThing	hemocyte differentiation	The process in which a relatively unspecialized cell acquires the characteristics of a mature hemocyte. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen.	tmpzr1t_l9r_go_relaxed.owl	arthropod blood cell differentiation													biological_process											owl:Class	
GO:0002880	biolink:NamedThing	regulation of chronic inflammatory response to non-antigenic stimulus	Any process that modulates the frequency, rate, or extent of a chronic inflammatory response to a non-antigenic stimulus.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0002676	biolink:NamedThing	regulation of chronic inflammatory response	Any process that modulates the frequency, rate, or extent of a chronic inflammatory response.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0002732	biolink:NamedThing	positive regulation of dendritic cell cytokine production	Any process that activates or increases the frequency, rate, or extent of dendritic cell cytokine production.	tmpzr1t_l9r_go_relaxed.owl	activation of dendritic cell cytokine production|upregulation of dendritic cell cytokine production|up-regulation of dendritic cell cytokine production|up regulation of dendritic cell cytokine production|stimulation of dendritic cell cytokine production													biological_process											owl:Class	
GO:0002730	biolink:NamedThing	regulation of dendritic cell cytokine production	Any process that modulates the frequency, rate, or extent of dendritic cell cytokine production.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0090315	biolink:NamedThing	negative regulation of protein targeting to membrane	Any process that decreases the frequency, rate or extent of the process of directing proteins towards a membrane, usually using signals contained within the protein.	tmpzr1t_l9r_go_relaxed.owl								tb	2010-04-16T03:42:22Z					biological_process											owl:Class	
GO:0002662	biolink:NamedThing	negative regulation of B cell tolerance induction	Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell tolerance induction.	tmpzr1t_l9r_go_relaxed.owl	inhibition of B cell tolerance induction|negative regulation of B-lymphocyte tolerance induction|downregulation of B cell tolerance induction|down-regulation of B cell tolerance induction|down regulation of B cell tolerance induction|negative regulation of B lymphocyte tolerance induction|negative regulation of B-cell tolerance induction													biological_process											owl:Class	
GO:0002661	biolink:NamedThing	regulation of B cell tolerance induction	Any process that modulates the frequency, rate, or extent of B cell tolerance induction.	tmpzr1t_l9r_go_relaxed.owl	regulation of B-lymphocyte tolerance induction|regulation of B-cell tolerance induction|regulation of B lymphocyte tolerance induction													biological_process											owl:Class	
GO:0051799	biolink:NamedThing	negative regulation of hair follicle development	Any process that stops, prevents, or reduces the frequency, rate or extent of hair follicle development.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of hair follicle development|inhibition of hair follicle development|downregulation of hair follicle development|down regulation of hair follicle development													biological_process											owl:Class	
GO:0110157	biolink:NamedThing	reelin complex	An extracellular complex that binds lipoprotein receptors VLDLR and APOER2, cadherin-related neuronal receptors (CNRs) or alpha3beta1 integrin and induces various downstream, reelin-dependent, phosphorylation cascades. It ultimately affects polarization, differentiation, neuronal migration and layer formation in the embryonic brain and neuron growth, maturation, and synaptic activity in the postnatal and adult brain.	tmpzr1t_l9r_go_relaxed.owl								kmv	2019-07-15T15:10:58Z					cellular_component											owl:Class	
GO:0036090	biolink:NamedThing	cleavage furrow ingression	Advancement of the cleavage furrow from the outside of the cell inward towards the center of the cell. The cleavage furrow acts as a 'purse string' which draws tight to separate daughter cells during cytokinesis and partition the cytoplasm between the two daughter cells. The furrow ingresses until a cytoplasmic bridge is formed.	tmpzr1t_l9r_go_relaxed.owl	cleavage furrow contraction					Consider also annotating to 'contractile ring contraction involved in cell cycle cytokinesis ; GO:0000916'.		bf	2012-01-10T02:46:05Z					biological_process											owl:Class	
GO:0099024	biolink:NamedThing	plasma membrane invagination	An infolding of the plasma membrane.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0034021	biolink:NamedThing	response to silicon dioxide	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a silicon dioxide stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to silica|response to silox													biological_process											owl:Class	
GO:0032412	biolink:NamedThing	regulation of ion transmembrane transporter activity	Any process that modulates the activity of an ion transporter.	tmpzr1t_l9r_go_relaxed.owl	regulation of ion transporter activity													biological_process											owl:Class	
GO:0022898	biolink:NamedThing	regulation of transmembrane transporter activity	Any process that modulates the frequency, rate or extent of transmembrane transporter activity.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0015462	biolink:NamedThing	ABC-type protein transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + protein(out) = ADP + phosphate + protein(in).	tmpzr1t_l9r_go_relaxed.owl	ATPase-coupled protein transmembrane transporter activity|protein-transmembrane transporting ATPase activity|protein ABC transporter|protein-transporting ATPase activity|ABC-type protein transmembrane transporter activity|pilin/fimbrilin exporter activity				EC:7.4.2.5	Enzymes with this activity include bacterial enzymes dedicated to the secretion of one or several closely related proteins belonging to the toxin, protease and lipase families, for example alpha-hemolysin, cyclolysin, colicin V, siderophores, bacteriocin, subtilin, competence factor and pediocin (from EC:7.4.2.5).								molecular_function											owl:Class	
GO:0140359	biolink:NamedThing	ABC-type transporter activity	Primary active transporter characterized by two nucleotide-binding domains and two transmembrane domains. Uses the energy generated from ATP hydrolysis to drive the transport of a substance across a membrane.	tmpzr1t_l9r_go_relaxed.owl	ABC-type efflux permease activity|ABC-type efflux porter activity|ATP-binding cassette (ABC) transporter activity|ABC-type uptake permease activity|ATP binding cassette transporter|ABC-type transmembrane transporter activity|ATP-binding cassette transporter|ABC transporter	https://github.com/geneontology/go-ontology/issues/20529|https://github.com/geneontology/go-ontology/issues/21273			Reactome:R-HSA-266070|Reactome:R-HSA-5683325|Reactome:R-HSA-9661405|Wikipedia:ATP-binding_cassette_transporter|Reactome:R-HSA-5223313|Reactome:R-HSA-5387389|Reactome:R-HSA-5362459|TC:3.A.1			pg	2019-06-25T19:08:14Z					molecular_function											owl:Class	
GO:0018190	biolink:NamedThing	protein octanoylation	The modification of a protein amino acid by formation of an ester or amide with octanoic acid.	tmpzr1t_l9r_go_relaxed.owl	protein amino acid octanoylation													biological_process											owl:Class	
GO:0006497	biolink:NamedThing	protein lipidation	The covalent attachment of lipid groups to an amino acid in a protein.	tmpzr1t_l9r_go_relaxed.owl	lipid:protein modification|protein amino acid lipidation				RESID:AA0308|RESID:AA0309|RESID:AA0307|RESID:AA0078|RESID:AA0059|RESID:AA0103|RESID:AA0080|RESID:AA0158|RESID:AA0107|RESID:AA0223|RESID:AA0077|RESID:AA0316|RESID:AA0106|RESID:AA0060|RESID:AA0290|RESID:AA0102|RESID:AA0161|RESID:AA0159|RESID:AA0104|RESID:AA0163|RESID:AA0079|RESID:AA0162|RESID:AA0160|RESID:AA0166	For non-covalent interactions with a lipid, consider instead the term 'lipid binding ; GO:0008289' and its children.						GO:0042050		biological_process											owl:Class	
GO:2001155	biolink:NamedThing	negative regulation of glycolytic fermentation to ethanol	Any process that stops, prevents or reduces the frequency, rate or extent of glucose catabolic process to ethanol.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of glucose fermentation to ethanol|negative regulation of ethanol fermentation							mcc	2011-10-27T02:39:05Z					biological_process											owl:Class	
GO:0052865	biolink:NamedThing	1-deoxy-D-xylulose 5-phosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of 1-deoxy-D-xylulose 5-phosphate, the 5-phospho derivative of 1-deoxy-D-xylulose. 1-deoxy-D-xylulose 5-phosphate is an intermediate in the non-mevalonate pathway and a common precursor for isoprenoid, thiamin, and pyridoxol biosynthesis.	tmpzr1t_l9r_go_relaxed.owl	1-deoxy-D-xylulose 5-phosphate synthesis|(2R,3S)-2,3-dihydroxy-4-oxopentyl dihydrogen phosphate formation|(2R,3S)-2,3-dihydroxy-4-oxopentyl dihydrogen phosphate biosynthetic process|(2R,3S)-2,3-dihydroxy-4-oxopentyl dihydrogen phosphate synthesis|1-deoxy-D-xylulose 5-phosphate formation|1-deoxy-D-xylulose 5-phosphate anabolism|1-deoxy-D-xylulose 5-phosphate biosynthesis|(2R,3S)-2,3-dihydroxy-4-oxopentyl dihydrogen phosphate biosynthesis|(2R,3S)-2,3-dihydroxy-4-oxopentyl dihydrogen phosphate anabolism				UniPathway:UPA00064									biological_process											owl:Class	
GO:0061088	biolink:NamedThing	regulation of sequestering of zinc ion	Any process that modulates the rate, frequency, or extent of sequestering of zinc ion. Sequestering of zinc ion is the process of binding or confining zinc ions such that they are separated from other components of a biological system.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-04-26T01:38:53Z					biological_process											owl:Class	
GO:0034417	biolink:NamedThing	bisphosphoglycerate 3-phosphatase activity	Catalysis of the reaction: 2,3-diphosphoglycerate + H2O = 2-phospho-D-glycerate + phosphate.	tmpzr1t_l9r_go_relaxed.owl	2,3-bisphospho-D-glycerate 3-phosphohydrolase activity				EC:3.1.3.80|KEGG_REACTION:R09532|RHEA:27381|MetaCyc:RXN-11102									molecular_function											owl:Class	
GO:0034416	biolink:NamedThing	bisphosphoglycerate phosphatase activity	Catalysis of the reaction: 2,3-diphosphoglycerate + H2O = phosphoglycerate + phosphate.	tmpzr1t_l9r_go_relaxed.owl	diphosphoglycerate phosphatase activity|glycerate-2,3-diphosphate phosphatase activity|2,3-bisphosphoglycerate phosphatase activity|2,3-diphosphoglycerate phosphatase activity|2,3-diphosphoglyceric acid phosphatase activity													molecular_function											owl:Class	
GO:0032816	biolink:NamedThing	positive regulation of natural killer cell activation	Any process that activates or increases the frequency, rate or extent of natural killer cell activation.	tmpzr1t_l9r_go_relaxed.owl	stimulation of natural killer cell activation|positive regulation of NK cell activation|activation of natural killer cell activation|up regulation of natural killer cell activation|upregulation of natural killer cell activation|up-regulation of natural killer cell activation													biological_process											owl:Class	
GO:0051251	biolink:NamedThing	positive regulation of lymphocyte activation	Any process that activates or increases the frequency, rate or extent of lymphocyte activation.	tmpzr1t_l9r_go_relaxed.owl	up regulation of lymphocyte activation|upregulation of lymphocyte activation|activation of lymphocyte activation|stimulation of lymphocyte activation|up-regulation of lymphocyte activation													biological_process											owl:Class	
GO:0051414	biolink:NamedThing	response to cortisol	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cortisol stimulus. Cortisol is the major natural glucocorticoid synthesized in the zona fasciculata of the adrenal cortex; it affects the metabolism of glucose, protein, and fats and has appreciable mineralocorticoid activity. It also regulates the immune system and affects many other functions.	tmpzr1t_l9r_go_relaxed.owl	response to hydrocortisone stimulus|response to cortisol stimulus													biological_process											owl:Class	
GO:0060493	biolink:NamedThing	mesenchymal-endodermal cell signaling involved in lung induction	Any process that mediates the transfer of information from a mesenchymal cell to an endodermal cell in the foregut and contributes to the formation of the lung bud.	tmpzr1t_l9r_go_relaxed.owl	mesenchymal-endodermal cell signalling involved in lung induction													biological_process											owl:Class	
GO:0060497	biolink:NamedThing	mesenchymal-endodermal cell signaling	Any process that mediates the transfer of information between a mesenchymal cell and an endodermal cell.	tmpzr1t_l9r_go_relaxed.owl	mesenchymal-endodermal cell signalling													biological_process											owl:Class	
GO:0060819	biolink:NamedThing	inactivation of X chromosome by genetic imprinting	Compensating for the two-fold variation in X-chromosome:autosome ratios between sexes by a global inactivation of all, or most of, the genes on one of the X-chromosomes in the XX sex by genetic imprinting.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-08-11T10:56:06Z					biological_process											owl:Class	
GO:0006349	biolink:NamedThing	regulation of gene expression by genetic imprinting	Heritable alterations in the activity of a gene that depend on whether it passed through the paternal or the maternal germline, but that are not encoded by DNA itself.	tmpzr1t_l9r_go_relaxed.owl	regulation of gene expression by DNA imprinting				Wikipedia:Genomic_imprinting									biological_process											owl:Class	
GO:0090105	biolink:NamedThing	pancreatic E cell development	The process whose specific outcome is the progression of a pancreatic E cell over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-11-18T11:51:00Z					biological_process											owl:Class	
GO:0035863	biolink:NamedThing	dITP catabolic process	The chemical reactions and pathways resulting in the breakdown of dITP, a deoxyinosine phosphate compound having a triphosphate group at the 5'-position.	tmpzr1t_l9r_go_relaxed.owl	dITP breakdown|deoxyinosine 5'-triphosphate catabolic process|2'-Deoxyinosine 5'-triphosphate catabolic process|dITP catabolism|deoxyinosine triphosphate (2'-deoxyinosine 5'-triphosphate) catabolic process|2'-Deoxyinosine-5'-triphosphate catabolic process|dITP degradation							bf	2011-05-25T02:55:21Z					biological_process											owl:Class	
GO:0009155	biolink:NamedThing	purine deoxyribonucleotide catabolic process	The chemical reactions and pathways resulting in the breakdown of purine deoxyribonucleotide, a compound consisting of deoxyribonucleoside (a purine base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.	tmpzr1t_l9r_go_relaxed.owl	purine deoxyribonucleotide catabolism|purine deoxyribonucleotide degradation|purine deoxyribonucleotide breakdown													biological_process											owl:Class	
GO:2000363	biolink:NamedThing	positive regulation of prostaglandin-E synthase activity	Any process that activates or increases the frequency, rate or extent of prostaglandin-E synthase activity.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of prostaglandin R-prostaglandin E isomerase activity|positive regulation of PGE2 isomerase activity|positive regulation of PGH-PGE isomerase activity|positive regulation of prostaglandin endoperoxide E isomerase activity|positive regulation of prostaglandin H-E isomerase activity|positive regulation of endoperoxide isomerase activity|positive regulation of (5Z,13E)-(15S)-9alpha,11alpha-epidioxy-15-hydroxyprosta-5,13-dienoate E-isomerase activity|positive regulation of prostaglandin endoperoxide E2 isomerase activity|positive regulation of PGE isomerase activity|positive regulation of Prostaglandin-H(2) E-isomerase activity|positive regulation of prostaglandin-H2 E-isomerase activity							bf	2011-02-03T04:05:42Z					biological_process											owl:Class	
GO:0010912	biolink:NamedThing	positive regulation of isomerase activity	Any process that increases the activity of an isomerase. An isomerase catalyzes the geometric or structural changes within one molecule. Isomerase is the systematic name for any enzyme of EC class 5.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0036494	biolink:NamedThing	positive regulation of translation initiation in response to endoplasmic reticulum stress	Any process that activates, or increases the frequency, rate or extent of translation initiation as a result of endoplasmic reticulum stress.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of translation initiation in response to ER stress							bf	2015-02-05T10:11:32Z					biological_process											owl:Class	
GO:0032058	biolink:NamedThing	positive regulation of translational initiation in response to stress	Any process that activates or increases the frequency, rate or extent of translation initiation as a result of a stimulus indicating the organism is under stress.	tmpzr1t_l9r_go_relaxed.owl	upregulation of translation initiation in response to stress|stimulation of translation initiation in response to stress|up regulation of translation initiation in response to stress|activation of translation initiation in response to stress|up-regulation of translation initiation in response to stress													biological_process											owl:Class	
GO:1901040	biolink:NamedThing	negative regulation of peptide antigen transport	Any process that stops, prevents or reduces the frequency, rate or extent of peptide antigen transport.	tmpzr1t_l9r_go_relaxed.owl	inhibition of peptide antigen transport|down regulation of peptide antigen transport|downregulation of peptide antigen transport|down-regulation of peptide antigen transport							bf	2012-06-22T04:08:18Z					biological_process											owl:Class	
GO:0045744	biolink:NamedThing	negative regulation of G protein-coupled receptor signaling pathway	Any process that stops, prevents, or reduces the frequency, rate or extent of G protein-coupled receptor signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of G protein coupled receptor protein signaling pathway|negative regulation of GPCR protein signaling pathway|negative regulation of G-protein coupled receptor protein signalling pathway|down-regulation of G-protein coupled receptor protein signaling pathway|negative regulation of G-protein coupled receptor protein signaling pathway|downregulation of G-protein coupled receptor protein signaling pathway|down regulation of G-protein coupled receptor protein signaling pathway|inhibition of G-protein coupled receptor protein signaling pathway|negative regulation of G-protein-coupled receptor protein signalling pathway|negative regulation of GPCR protein signalling pathway|negative regulation of G protein coupled receptor protein signalling pathway													biological_process											owl:Class	
GO:0071432	biolink:NamedThing	peptide mating pheromone maturation involved in positive regulation of conjugation with cellular fusion	The formation of a mature peptide mating pheromone by proteolysis and/or modification of a peptide precursor, occurring in the context of conjugation with cellular fusion.	tmpzr1t_l9r_go_relaxed.owl	peptide mating pheromone processing involved in conjugation with cellular fusion|a-factor processing (proteolytic)|peptide mating pheromone formation involved in conjugation with cellular fusion|alpha-factor maturation|mating-type peptide pheromone maturation involved in conjugation with cellular fusion							mah	2009-12-16T10:46:50Z					biological_process											owl:Class	
GO:0007323	biolink:NamedThing	peptide pheromone maturation	The generation of a mature, active peptide pheromone via processes unique to its processing and modification. An example of this process is found in Saccharomyces cerevisiae.	tmpzr1t_l9r_go_relaxed.owl	pheromone processing											GO:0007324|GO:0007326|GO:0046613		biological_process											owl:Class	
GO:0034666	biolink:NamedThing	integrin alpha2-beta1 complex	An integrin complex that comprises one alpha2 subunit and one beta1 subunit.	tmpzr1t_l9r_go_relaxed.owl	VLA-2 complex|ITGA2-ITGB1 complex													cellular_component											owl:Class	
GO:0075111	biolink:NamedThing	suppression by symbiont of host receptor-mediated signal transduction	Any process in which the symbiont stops, prevents, or reduces the frequency, rate or extent of receptor-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	negative regulation by symbiont of host receptor-mediated signal transduction					Note that this term is used to annotate gene products of the symbiont. To annotate host gene products, consider the biological process term "negative regulation by host of symbiont receptor-mediated signal transduction ; GO:0075080".								biological_process											owl:Class	
GO:0052029	biolink:NamedThing	suppression by symbiont of host signal transduction pathway	Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of the host signal transduction pathways, the cascade of processes by which a signal interacts with a receptor. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	down regulation by symbiont of host signal transduction pathway|negative regulation by organism of signal transduction in other organism involved in symbiotic interaction|down-regulation by symbiont of host signal transduction pathway|downregulation by symbiont of host signal transduction pathway|inhibition by symbiont of host signal transduction pathway|negative modulation by organism of host signal transduction pathway|negative regulation by symbiont of host signal transduction pathway											GO:0052493		biological_process											owl:Class	
GO:0045753	biolink:NamedThing	negative regulation of acetate catabolic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of acetate.	tmpzr1t_l9r_go_relaxed.owl	inhibition of acetate catabolic process|negative regulation of acetate catabolism|downregulation of acetate catabolic process|negative regulation of acetate breakdown|down-regulation of acetate catabolic process|down regulation of acetate catabolic process|negative regulation of acetate degradation													biological_process											owl:Class	
GO:1901274	biolink:NamedThing	2-dehydro-3-deoxy-D-gluconic acid biosynthetic process	The chemical reactions and pathways resulting in the formation of 2-dehydro-3-deoxy-D-gluconic acid.	tmpzr1t_l9r_go_relaxed.owl	2-dehydro-3-deoxy-D-gluconic acid formation|2-dehydro-3-deoxy-D-gluconic acid anabolism|2-dehydro-3-deoxy-D-gluconic acid biosynthesis|2-dehydro-3-deoxy-D-gluconic acid synthesis							yaf	2012-08-17T14:46:44Z					biological_process											owl:Class	
GO:0046364	biolink:NamedThing	monosaccharide biosynthetic process	The chemical reactions and pathways resulting in the formation of monosaccharides, polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms.	tmpzr1t_l9r_go_relaxed.owl	monosaccharide synthesis|monosaccharide formation|monosaccharide biosynthesis|monosaccharide anabolism													biological_process											owl:Class	
GO:0046006	biolink:NamedThing	regulation of activated T cell proliferation	Any process that modulates the frequency, rate or extent of activated T cell proliferation.	tmpzr1t_l9r_go_relaxed.owl	regulation of activated T-cell proliferation|regulation of activated T lymphocyte proliferation|regulation of activated T-lymphocyte proliferation													biological_process											owl:Class	
GO:0001928	biolink:NamedThing	regulation of exocyst assembly	Any process that modulates the frequency, rate or extent of exocyst assembly.	tmpzr1t_l9r_go_relaxed.owl						Note that the assembly is regulated by several small GTPases of the Rab and Rho families.								biological_process											owl:Class	
GO:0036180	biolink:NamedThing	filamentous growth of a population of unicellular organisms in response to biotic stimulus	The process in which a group of unicellular organisms grow in a threadlike, filamentous shape in response to a biotic (living) stimulus.	tmpzr1t_l9r_go_relaxed.owl								bf	2012-03-30T04:12:40Z					biological_process											owl:Class	
GO:0044182	biolink:NamedThing	filamentous growth of a population of unicellular organisms	The process in which a group of unicellular organisms grow in a threadlike, filamentous shape.	tmpzr1t_l9r_go_relaxed.owl								jl	2009-09-25T10:18:32Z					biological_process											owl:Class	
GO:1904478	biolink:NamedThing	regulation of intestinal absorption	Any process that modulates the frequency, rate or extent of intestinal absorption.	tmpzr1t_l9r_go_relaxed.owl								rl	2015-07-13T15:58:47Z					biological_process											owl:Class	
GO:0044058	biolink:NamedThing	regulation of digestive system process	Any process that modulates the frequency, rate or extent of a digestive system process, a physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0035603	biolink:NamedThing	fibroblast growth factor receptor signaling pathway involved in hemopoiesis	The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands, which contributes to hemopoiesis.	tmpzr1t_l9r_go_relaxed.owl	FGFR signaling pathway involved in hematopoiesis|fibroblast growth factor receptor signalling pathway involved in hemopoiesis|FGF receptor signaling pathway involved in hematopoiesis|fibroblast growth factor receptor signaling pathway involved in hematopoiesis							bf	2010-11-15T11:09:46Z					biological_process											owl:Class	
GO:0008543	biolink:NamedThing	fibroblast growth factor receptor signaling pathway	The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands.	tmpzr1t_l9r_go_relaxed.owl	FGF receptor signaling pathway|FGFR signaling pathway|fibroblast growth factor receptor signalling pathway|FGF receptor signalling pathway													biological_process											owl:Class	
GO:0009610	biolink:NamedThing	response to symbiotic fungus	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a symbiotic fungus, a fungus living in close physical association with another organism.	tmpzr1t_l9r_go_relaxed.owl	response to symbiotic fungi													biological_process											owl:Class	
GO:0009620	biolink:NamedThing	response to fungus	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a fungus.	tmpzr1t_l9r_go_relaxed.owl	response to fungi											GO:0009621		biological_process											owl:Class	
GO:0098628	biolink:NamedThing	peptidyl-N-phospho-arginine dephosphorylation	The removal of phosphate residues from peptidyl-N-phospho-arginine to form peptidyl-arginine.	tmpzr1t_l9r_go_relaxed.owl								dos	2014-04-17T18:03:31Z					biological_process											owl:Class	
GO:0006470	biolink:NamedThing	protein dephosphorylation	The process of removing one or more phosphoric residues from a protein.	tmpzr1t_l9r_go_relaxed.owl	protein amino acid dephosphorylation													biological_process											owl:Class	
GO:0005914	biolink:NamedThing	spot adherens junction	A small cell-cell adherens junction assembled during the cellularization stage of insect embyrogenesis; spot adherens junctions later fuse to form the zonula adherens.	tmpzr1t_l9r_go_relaxed.owl	punctum adherens|dense plaque													cellular_component											owl:Class	
GO:0005912	biolink:NamedThing	adherens junction	A cell-cell junction composed of the epithelial cadherin-catenin complex. The epithelial cadherins, or E-cadherins, of each interacting cell extend through the plasma membrane into the extracellular space and bind to each other. The E-cadherins bind to catenins on the cytoplasmic side of the membrane, where the E-cadherin-catenin complex binds to cytoskeletal components and regulatory and signaling molecules.	tmpzr1t_l9r_go_relaxed.owl	cell-cell adherens junction				Wikipedia:Adherens_junction							GO:0005913		cellular_component											owl:Class	
GO:1903382	biolink:NamedThing	negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway	Any process that stops, prevents or reduces the frequency, rate or extent of an endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	down regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway|down regulation of neuron intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress|downregulation of neuron intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress|downregulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway|down regulation of ER stress-induced neuron intrinsic apoptotic signaling pathway|downregulation of ER stress-induced neuron intrinsic apoptotic signaling pathway|inhibition of ER stress-induced neuron intrinsic apoptotic signaling pathway|inhibition of neuron intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress|inhibition of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway|down-regulation of ER stress-induced neuron intrinsic apoptotic signaling pathway|negative regulation of ER stress-induced neuron intrinsic apoptotic signaling pathway|negative regulation of neuron intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress|down-regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway|down-regulation of neuron intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress							bf	2014-08-27T08:45:38Z					biological_process											owl:Class	
GO:0015225	biolink:NamedThing	biotin transmembrane transporter activity	Enables the transfer of biotin from one side of a membrane to the other. Biotin is cis-tetrahydro-2-oxothieno(3,4-d)imidazoline-4-valeric acid; the (+) enantiomer is very widely distributed in cells and serves as a carrier in a number of enzymatic beta-carboxylation reactions.	tmpzr1t_l9r_go_relaxed.owl	biotin transporter activity|vitamin H transporter activity|vitamin B7 transporter activity				RHEA:28458			al	2012-11-08T14:18:56Z			GO:1901603		molecular_function											owl:Class	
GO:0006681	biolink:NamedThing	galactosylceramide metabolic process	The chemical reactions and pathways involving galactosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of galactose by a ceramide group.	tmpzr1t_l9r_go_relaxed.owl	galactosylceramide metabolism													biological_process											owl:Class	
GO:1900961	biolink:NamedThing	positive regulation of 17-methylnonadec-1-ene metabolic process	Any process that activates or increases the frequency, rate or extent of 17-methylnonadec-1-ene metabolic process.	tmpzr1t_l9r_go_relaxed.owl	upregulation of 17-methylnonadec-1-ene metabolism|positive regulation of 17-methylnonadec-1-ene metabolism|activation of 17-methylnonadec-1-ene metabolism|up regulation of 17-methylnonadec-1-ene metabolism|upregulation of 17-methylnonadec-1-ene metabolic process|up-regulation of 17-methylnonadec-1-ene metabolism|up-regulation of 17-methylnonadec-1-ene metabolic process|activation of 17-methylnonadec-1-ene metabolic process|up regulation of 17-methylnonadec-1-ene metabolic process							tt	2012-06-14T03:29:59Z					biological_process											owl:Class	
GO:1900959	biolink:NamedThing	regulation of 17-methylnonadec-1-ene metabolic process	Any process that modulates the frequency, rate or extent of 17-methylnonadec-1-ene metabolic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of 17-methylnonadec-1-ene metabolism							tt	2012-06-14T03:29:27Z					biological_process											owl:Class	
GO:2000911	biolink:NamedThing	positive regulation of sterol import	Any process that activates or increases the frequency, rate or extent of sterol import.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of sterol influx|positive regulation of sterol uptake							bf	2011-07-29T01:25:17Z					biological_process											owl:Class	
GO:0061511	biolink:NamedThing	centriole elongation	The centrosome organization process by which a centriole increases in length as part of the process of replication.	tmpzr1t_l9r_go_relaxed.owl								dph	2013-03-22T09:06:27Z					biological_process											owl:Class	
GO:0022402	biolink:NamedThing	cell cycle process	The cellular process that ensures successive accurate and complete genome replication and chromosome segregation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1905717	biolink:NamedThing	positive regulation of cornification	Any process that activates or increases the frequency, rate or extent of cornification.	tmpzr1t_l9r_go_relaxed.owl	up regulation of cornification|activation of cornification|up-regulation of cornification|upregulation of cornification							pga	2016-11-24T13:53:21Z					biological_process											owl:Class	
GO:0070664	biolink:NamedThing	negative regulation of leukocyte proliferation	Any process that stops, prevents, or reduces the frequency, rate or extent of leukocyte proliferation.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of leukocyte proliferation|down regulation of leukocyte proliferation|inhibition of leukocyte proliferation|downregulation of leukocyte proliferation							mah	2009-05-28T05:34:50Z					biological_process											owl:Class	
GO:0110140	biolink:NamedThing	flagellum attachment zone organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a flagellum attachment zone. FAZ is a network of cytoskeletal and membranous connections responsible for the lateral attachment of the cilium to the cell body in some trypanosomatid species.	tmpzr1t_l9r_go_relaxed.owl	flagellum attachment zone organisation|FAZ organization							kmv	2019-03-04T19:55:50Z					biological_process											owl:Class	
GO:0034330	biolink:NamedThing	cell junction organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cell junction. A cell junction is a specialized region of connection between two cells or between a cell and the extracellular matrix.	tmpzr1t_l9r_go_relaxed.owl	cell junction organisation|cell junction biogenesis|cell junction assembly and maintenance													biological_process											owl:Class	
GO:1904028	biolink:NamedThing	positive regulation of collagen fibril organization	Any process that activates or increases the frequency, rate or extent of collagen fibril organization.	tmpzr1t_l9r_go_relaxed.owl	up regulation of collagen fibril organization|up-regulation of collagen fibril organisation|up-regulation of collagen fibril organization|positive regulation of fibrillar collagen organization|activation of fibrillar collagen organization|up regulation of fibrillar collagen organization|up regulation of collagen fibril organisation|activation of collagen fibril organization|upregulation of collagen fibril organisation|activation of collagen fibril organisation|positive regulation of collagen fibril organisation|up-regulation of fibrillar collagen organization|upregulation of collagen fibril organization|upregulation of fibrillar collagen organization							ae	2015-03-12T12:37:06Z					biological_process											owl:Class	
GO:1904026	biolink:NamedThing	regulation of collagen fibril organization	Any process that modulates the frequency, rate or extent of collagen fibril organization.	tmpzr1t_l9r_go_relaxed.owl	regulation of collagen fibril organisation|regulation of fibrillar collagen organization|regulation of collagen fibrillogenesis							ae	2015-03-12T12:36:52Z					biological_process											owl:Class	
GO:0120082	biolink:NamedThing	smooth endoplasmic reticulum cisterna	A subcompartment of the smooth endoplasmic reticulum consisting of lumenal expansion into a flattened, disc-shaped cavity.	tmpzr1t_l9r_go_relaxed.owl								krc	2017-07-05T23:32:11Z					cellular_component											owl:Class	
GO:0140210	biolink:NamedThing	protein transport along microtubule to kinetochore	Any process in which a protein is transported to the kinetochore along a microtubule.	tmpzr1t_l9r_go_relaxed.owl								pg	2018-03-22T07:05:21Z					biological_process											owl:Class	
GO:0071556	biolink:NamedThing	integral component of lumenal side of endoplasmic reticulum membrane	The component of the endoplasmic reticulum membrane consisting of the gene products that penetrate only the lumenal side of the membrane.	tmpzr1t_l9r_go_relaxed.owl	integral to lumenal side of ER membrane|integral to lumenal leaflet of endoplasmic reticulum membrane|integral to lumenal side of endoplasmic reticulum membrane|integral to ER membrane, lumenal side							mah	2010-01-15T10:56:58Z					cellular_component											owl:Class	
GO:0030176	biolink:NamedThing	integral component of endoplasmic reticulum membrane	The component of the endoplasmic reticulum membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.	tmpzr1t_l9r_go_relaxed.owl	integral to ER membrane|integral to endoplasmic reticulum membrane|ER integral membrane protein													cellular_component											owl:Class	
GO:0030250	biolink:NamedThing	guanylate cyclase activator activity	Binds to and increases the activity of guanylate cyclase.	tmpzr1t_l9r_go_relaxed.owl	guanylin													molecular_function											owl:Class	
GO:0120248	biolink:NamedThing	acetylenic compound catabolic process	The chemical reactions and pathways resulting in the breakdown of an acetylenic compound, any compound which contains a carbon-carbon triple bond (aka C#C).	tmpzr1t_l9r_go_relaxed.owl	alkyne substituted compound catabolism|alkyne substituted compound degradation|alkyne substituted compound breakdown|alkyne substituted compound catabolic process	https://github.com/geneontology/go-ontology/issues/19842						krc	2020-08-18T01:02:52Z					biological_process											owl:Class	
GO:0120246	biolink:NamedThing	acetylenic compound metabolic process	The chemical reactions and pathways involving an acetylenic compound, any compound which contains a carbon-carbon triple bond (aka C#C).	tmpzr1t_l9r_go_relaxed.owl	alkyne substituted compound metabolism|alkyne substituted compound metabolic process	https://github.com/geneontology/go-ontology/issues/19842						krc	2020-08-18T00:54:23Z					biological_process											owl:Class	
GO:0034665	biolink:NamedThing	integrin alpha1-beta1 complex	An integrin complex that comprises one alpha1 subunit and one beta1 subunit.	tmpzr1t_l9r_go_relaxed.owl	ITGA1-ITGB1 complex|VLA-1 complex|alpha1-beta1 integrin complex													cellular_component											owl:Class	
GO:0047085	biolink:NamedThing	hydroxyphenylacetonitrile 2-monooxygenase activity	Catalysis of the reaction: 4-hydroxyphenylacetonitrile + H(+) + NADPH + O(2) = 4-hydroxymandelonitrile + H(2)O + NADP(+).	tmpzr1t_l9r_go_relaxed.owl	4-hydroxyphenylacetonitrile,NADPH:oxygen oxidoreductase (2-hydroxylating)|4-hydroxyphenylacetonitrile hydroxylase activity|4-hydroxyphenylacetonitrile monooxygenase activity				KEGG_REACTION:R02708|MetaCyc:1.14.13.42-RXN|RHEA:23740									molecular_function											owl:Class	
GO:1903243	biolink:NamedThing	negative regulation of cardiac muscle hypertrophy in response to stress	Any process that stops, prevents or reduces the frequency, rate or extent of cardiac muscle hypertrophy in response to stress.	tmpzr1t_l9r_go_relaxed.owl	down regulation of cardiac muscle hypertrophy in response to stress|downregulation of cardiac muscle hypertrophy in response to stress|down-regulation of cardiac muscle hypertrophy in response to stress|inhibition of cardiac muscle hypertrophy in response to stress							rl	2014-08-01T16:31:42Z					biological_process											owl:Class	
GO:1903072	biolink:NamedThing	regulation of death-inducing signaling complex assembly	Any process that modulates the frequency, rate or extent of death-inducing signaling complex assembly.	tmpzr1t_l9r_go_relaxed.owl	regulation of death domain-mediated complex assembly|regulation of DISC assembly|regulation of death-inducing signaling complex formation|regulation of DD-mediated complex assembly|regulation of death-inducing signalling complex assembly|regulation of death domain-mediated complex assembly involved in extrinsic apoptotic pathway|regulation of DISC formation							bf	2014-05-29T09:33:13Z					biological_process											owl:Class	
GO:0120324	biolink:NamedThing	procyclogenesis	The morphological, biochemical and genetic changes that induce the differentiation of bloodstream form trypomastigotes into procyclic trypomastigotes in some of the Trypanosomatidae species such as Trypanosoma brucei. This process occurs inside the midgut of the tsetse fly vectors in T. brucei.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/pull/21924						krc	2021-08-03T19:53:17Z					biological_process											owl:Class	
GO:0044114	biolink:NamedThing	development of symbiont in host	The progression of an organism from an initial condition to a later condition, occurring within the cells or tissues of the host organism. This may (but not necessarily) include a filamentous growth form, and also can include secretion of proteases and lipases to break down host tissue. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	development of symbiont in host intercellular space|development of symbiont in host vascular tissue					This term partially replaces the obsolete term 'growth or development of symbiont in host ; GO:0044412'. See also 'biological process involved in interaction with host ; GO:0051701.		jl	2009-07-30T03:39:25Z			GO:0044122|GO:0044124		biological_process											owl:Class	
GO:1903704	biolink:NamedThing	negative regulation of production of siRNA involved in RNA interference	Any process that stops, prevents or reduces the frequency, rate or extent of production of siRNA involved in RNA interference.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of RNA interference, production of siRNA|down-regulation of production of guide RNAs involved in RNA interference|downregulation of production of siRNA involved in RNA interference|negative regulation of production of guide RNAs involved in RNA interference|down-regulation of production of siRNA involved in RNA interference|inhibition of production of guide RNAs involved in RNA interference|downregulation of RNA interference, production of siRNA|down regulation of RNA interference, production of guide RNAs|inhibition of RNA interference, production of siRNA|down regulation of production of guide RNAs involved in RNA interference|down regulation of production of siRNA involved in RNA interference|inhibition of production of siRNA involved in RNA interference|down regulation of RNA interference, production of siRNA|negative regulation of RNA interference, production of guide RNAs|downregulation of production of guide RNAs involved in RNA interference|down-regulation of RNA interference, production of guide RNAs|downregulation of RNA interference, production of guide RNAs|down-regulation of RNA interference, production of siRNA|inhibition of RNA interference, production of guide RNAs							nc	2014-12-03T15:13:22Z					biological_process											owl:Class	
GO:1904443	biolink:NamedThing	positive regulation of thyroid gland epithelial cell proliferation	Any process that activates or increases the frequency, rate or extent of thyroid gland epithelial cell proliferation.	tmpzr1t_l9r_go_relaxed.owl	upregulation of thyroid gland epithelial cell proliferation|up regulation of thyroid follicular cell proliferation|activation of thyroid gland epithelial cell proliferation|up-regulation of thyroid gland epithelial cell proliferation|up regulation of Hurthle cell proliferation|activation of Hurthle cell proliferation|upregulation of Hurthle cell proliferation|up regulation of thyroid gland epithelial cell proliferation|up-regulation of Hurthle cell proliferation|upregulation of thyroid follicular cell proliferation|activation of thyroid follicular cell proliferation|up-regulation of thyroid follicular cell proliferation|positive regulation of thyroid follicular cell proliferation|positive regulation of Hurthle cell proliferation							sl	2015-07-06T15:41:21Z					biological_process											owl:Class	
GO:0061430	biolink:NamedThing	bone trabecula morphogenesis	The process of shaping a trabecula in bone. A trabecula is a tissue element in the form of a small beam, strut or rod.	tmpzr1t_l9r_go_relaxed.owl								dph	2012-02-07T10:15:36Z					biological_process											owl:Class	
GO:0061383	biolink:NamedThing	trabecula morphogenesis	The process of shaping a trabecula in an organ. A trabecula is a small, often microscopic, tissue element in the form of a small beam, strut or rod, which generally has a mechanical function. Trabecula are usually but not necessarily, composed of dense collagenous tissue.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-12-02T08:51:45Z					biological_process											owl:Class	
GO:0031165	biolink:NamedThing	integral component of contractile vacuolar membrane	The component of the contractile vacuolar membrane consisting of gene products that have some part that penetrates at least one leaflet of the membrane bilayer. This component includes gene products that are buried in the bilayer with no exposure outside the bilayer.	tmpzr1t_l9r_go_relaxed.owl	integral to contractile vacuolar membrane													cellular_component											owl:Class	
GO:0031311	biolink:NamedThing	intrinsic component of contractile vacuolar membrane	The component of the contractile vacuolar membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.	tmpzr1t_l9r_go_relaxed.owl	intrinsic to contractile vacuolar membrane													cellular_component											owl:Class	
GO:0045597	biolink:NamedThing	positive regulation of cell differentiation	Any process that activates or increases the frequency, rate or extent of cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	up regulation of cell differentiation|upregulation of cell differentiation|activation of cell differentiation|stimulation of cell differentiation|up-regulation of cell differentiation													biological_process											owl:Class	
GO:0016581	biolink:NamedThing	NuRD complex	An approximately 2 MDa multi-subunit complex that exhibits ATP-dependent chromatin remodeling activity in addition to histone deacetylase (HDAC) activity, and has been shown to establish transcriptional repression of a number of target genes in vertebrates, invertebrates and fungi. Amongst its subunits, the NuRD complex contains histone deacetylases, histone binding proteins and Mi-2-like proteins.	tmpzr1t_l9r_go_relaxed.owl	NRD complex|Mi-2 complex|nucleosome remodeling and histone deacetylation complex													cellular_component											owl:Class	
GO:0000118	biolink:NamedThing	histone deacetylase complex	A protein complex that possesses histone deacetylase activity.	tmpzr1t_l9r_go_relaxed.owl	HDAC complex					Note that this term represents a location, not a function; the activity possessed by this complex is mentioned in the definition for the purpose of describing and distinguishing the complex. The function of this complex is represented by the molecular function term 'histone deacetylase activity ; GO:0004407'.								cellular_component											owl:Class	
GO:0031634	biolink:NamedThing	replication fork barrier binding	Binding to replication fork barriers, sites that inhibit the progress of replication forks.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1990837	biolink:NamedThing	sequence-specific double-stranded DNA binding	Binding to double-stranded DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA, e.g. promotor binding or rDNA binding.	tmpzr1t_l9r_go_relaxed.owl	sequence-specific dsDNA binding							sl	2015-08-25T17:30:06Z					molecular_function											owl:Class	
GO:1902565	biolink:NamedThing	positive regulation of neutrophil activation	Any process that activates or increases the frequency, rate or extent of neutrophil activation.	tmpzr1t_l9r_go_relaxed.owl	upregulation of neutrophil activation|up-regulation of neutrophil activation|up regulation of neutrophil activation|activation of neutrophil activation							ecu	2013-12-10T15:33:26Z					biological_process											owl:Class	
GO:1902563	biolink:NamedThing	regulation of neutrophil activation	Any process that modulates the frequency, rate or extent of neutrophil activation.	tmpzr1t_l9r_go_relaxed.owl								ecu	2013-12-10T15:33:08Z					biological_process											owl:Class	
GO:0060999	biolink:NamedThing	positive regulation of dendritic spine development	Any process that increases the rate, frequency, or extent of dendritic spine development, the process whose specific outcome is the progression of the dendritic spine over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-01-20T09:27:21Z					biological_process											owl:Class	
GO:0030238	biolink:NamedThing	male sex determination	The specification of male sex of an individual organism.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0061891	biolink:NamedThing	calcium ion sensor activity	Binding to and responding, e.g. by conformational change, to changes in the cellular level of calcium ions (Ca2+).	tmpzr1t_l9r_go_relaxed.owl								dph	2017-06-01T23:37:01Z					molecular_function											owl:Class	
GO:0002898	biolink:NamedThing	regulation of central B cell deletion	Any process that modulates the frequency, rate, or extent of central B cell deletion.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0043408	biolink:NamedThing	regulation of MAPK cascade	Any process that modulates the frequency, rate or extent of signal transduction mediated by the MAP kinase (MAPK) cascade.	tmpzr1t_l9r_go_relaxed.owl	regulation of mitogen-activated protein kinase kinase kinase cascade|regulation of mitogen activated protein kinase kinase kinase cascade|regulation of mitogen-activated protein kinase cascade|regulation of MAPKKK cascade|regulation of MAP kinase cascade|regulation of mitogen activated protein kinase cascade|regulation of MAP kinase kinase kinase cascade													biological_process											owl:Class	
GO:1904404	biolink:NamedThing	response to formaldehyde	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a formaldehyde stimulus.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-06-23T21:14:04Z					biological_process											owl:Class	
GO:0032355	biolink:NamedThing	response to estradiol	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by estradiol, a C18 steroid hormone hydroxylated at C3 and C17 that acts as a potent estrogen.	tmpzr1t_l9r_go_relaxed.owl	response to estradiol stimulus|response to E2 stimulus													biological_process											owl:Class	
GO:0060808	biolink:NamedThing	positive regulation of mesodermal to mesenchymal transition involved in gastrulation	Any process that increases the rate, frequency, or extent of epithelial to mesenchymal transition. Epithelial to mesenchymal transition where a mesodermal cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell as part of the process of gastrulation.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-08-06T02:32:53Z					biological_process											owl:Class	
GO:0010718	biolink:NamedThing	positive regulation of epithelial to mesenchymal transition	Any process that increases the rate, frequency, or extent of epithelial to mesenchymal transition. Epithelial to mesenchymal transition is where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0046071	biolink:NamedThing	dGTP biosynthetic process	The chemical reactions and pathways resulting in the formation of dGTP, guanosine triphosphate.	tmpzr1t_l9r_go_relaxed.owl	dGTP synthesis|dGTP biosynthesis|dGTP formation|dGTP anabolism													biological_process											owl:Class	
GO:0046070	biolink:NamedThing	dGTP metabolic process	The chemical reactions and pathways involving dGTP, guanosine triphosphate.	tmpzr1t_l9r_go_relaxed.owl	dGTP metabolism													biological_process											owl:Class	
GO:1903088	biolink:NamedThing	5-amino-1-ribofuranosylimidazole-4-carboxamide transmembrane transport	The process in which 5-amino-1-ribofuranosylimidazole-4-carboxamide is transported across a membrane.	tmpzr1t_l9r_go_relaxed.owl								mcc	2014-06-02T20:34:58Z					biological_process											owl:Class	
GO:0072353	biolink:NamedThing	cellular age-dependent response to reactive oxygen species	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of reactive oxygen species, where the change varies according to the age of the cell or organism.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-11-12T11:27:27Z					biological_process											owl:Class	
GO:0001315	biolink:NamedThing	age-dependent response to reactive oxygen species	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of reactive oxygen species, where the change varies according to the age of the cell or organism.	tmpzr1t_l9r_go_relaxed.owl	age-dependent response to active oxygen species|age-dependent response to reactive oxidative species|age-dependent response to ROI|age-dependent response to ROS|age-dependent response to reactive oxygen intermediate|age-dependent response to AOS													biological_process											owl:Class	
GO:0015789	biolink:NamedThing	UDP-N-acetylgalactosamine transmembrane transport	The directed movement of UDP-N-acetylgalactosamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. UDP-N-acetylgalactosamine is a substance composed of N-acetylgalactosamine, a common structural unit of oligosaccharides, in glycosidic linkage with uridine diphosphate.	tmpzr1t_l9r_go_relaxed.owl	UDP-N-acetylgalactosamine transport													biological_process											owl:Class	
GO:0005854	biolink:NamedThing	nascent polypeptide-associated complex	A heterodimeric protein complex that can reversibly bind to ribosomes, and is located in direct proximity to newly synthesized polypeptide chains as they emerge from the ribosome.	tmpzr1t_l9r_go_relaxed.owl	NAC|NACA													cellular_component											owl:Class	
GO:0043223	biolink:NamedThing	cytoplasmic SCF ubiquitin ligase complex	A ubiquitin ligase complex, located in the cytoplasm, in which a cullin from the Cul1 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by a Skp1 adaptor and an F-box protein. SCF complexes are involved in targeting proteins for degradation by the proteasome. The best characterized complexes are those from yeast and mammals (with core subunits named Cdc53/Cul1, Rbx1/Hrt1/Roc1).	tmpzr1t_l9r_go_relaxed.owl	cytoplasmic cullin complex|cytoplasmic Skp1/Cul1/F-box protein complex|cytoplasmic SCF complex													cellular_component											owl:Class	
GO:0090028	biolink:NamedThing	positive regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion	Any process that increases the frequency, rate or extent of pheromone-dependent signal transduction during conjugation with cellular fusion, a signal transduction process resulting in the relay, amplification or dampening of a signal generated in response to pheromone exposure in organisms that undergo conjugation with cellular fusion.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-08-03T10:25:27Z					biological_process											owl:Class	
GO:0010969	biolink:NamedThing	regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion	Any process that modulates the frequency, rate or extent of pheromone-dependent signal transduction during conjugation with cellular fusion, a signal transduction process resulting in the relay, amplification or dampening of a signal generated in response to pheromone exposure in organisms that undergo conjugation with cellular fusion.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-05-20T11:54:57Z					biological_process											owl:Class	
GO:0003241	biolink:NamedThing	growth involved in heart morphogenesis	Developmental growth that contributes to the shaping of the heart.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-10-13T11:28:46Z					biological_process											owl:Class	
GO:0006709	biolink:NamedThing	progesterone catabolic process	The chemical reactions and pathways resulting in the breakdown of progesterone, a steroid hormone produced in the ovary which prepares and maintains the uterus for pregnancy. Also found in plants.	tmpzr1t_l9r_go_relaxed.owl	progesterone breakdown|progesterone degradation|progesterone catabolism													biological_process											owl:Class	
GO:0120256	biolink:NamedThing	olefinic compound catabolic process	The chemical reactions and pathways resulting in the breakdown of an olefinic compound, any compound which contains a carbon-carbon double bond (aka C=C).	tmpzr1t_l9r_go_relaxed.owl	alkene substituted compound degradation|alkene substituted compound catabolic process|alkene substituted compound catabolism|alkene substituted compound breakdown	https://github.com/geneontology/go-ontology/issues/19936						krc	2020-09-02T23:30:41Z					biological_process											owl:Class	
GO:0019685	biolink:NamedThing	photosynthesis, dark reaction	A complex cycle of enzyme-mediated reactions which catalyzes the reduction of carbon dioxide to sugar. As well as carbon dioxide the cycle requires reducing power in the form of reduced nicotinamide adenine dinucleotide phosphate (NADP) and chemical energy in the form of adenosine triphosphate (ATP). The reduced NADP (NADPH) and ATP are produced by the 'light' reactions.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0016051	biolink:NamedThing	carbohydrate biosynthetic process	The chemical reactions and pathways resulting in the formation of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y.	tmpzr1t_l9r_go_relaxed.owl	carbohydrate biosynthesis|anabolic carbohydrate metabolic process|anabolic carbohydrate metabolism|carbohydrate anabolism|carbohydrate formation|carbohydrate synthesis											GO:0006093		biological_process											owl:Class	
GO:0061656	biolink:NamedThing	SUMO conjugating enzyme activity	Isoenergetic transfer of SUMO from one protein to another via the reaction X-SUMO + Y -> Y-SUMO + X, where both the X-SUMO and Y-SUMO linkages are thioester bonds between the C-terminal amino acid of SUMO and a sulfhydryl side group of a cysteine residue.	tmpzr1t_l9r_go_relaxed.owl	E2							dph	2014-11-06T13:33:20Z					molecular_function											owl:Class	
GO:0019789	biolink:NamedThing	SUMO transferase activity	Catalysis of the transfer of SUMO from one protein to another via the reaction X-SUMO + Y --> Y-SUMO + X, where both X-SUMO and Y-SUMO are covalent linkages.	tmpzr1t_l9r_go_relaxed.owl	SMT3 conjugating enzyme|SUMO conjugating enzyme activity				Reactome:R-HSA-4719413|Reactome:R-HSA-4551683|Reactome:R-HSA-3968362|Reactome:R-HSA-3782535|Reactome:R-HSA-3000348|Reactome:R-HSA-4551768|Reactome:R-HSA-5684052|Reactome:R-HSA-4551616|Reactome:R-HSA-4755479|Reactome:R-HSA-4568863|Reactome:R-HSA-3900047|Reactome:R-HSA-4570485|Reactome:R-HSA-3000411|Reactome:R-HSA-3927959|Reactome:R-HSA-4341070|Reactome:R-HSA-3900070|Reactome:R-HSA-4086059|Reactome:R-HSA-4568846|Reactome:R-HSA-4570528|Reactome:R-HSA-5228525|Reactome:R-HSA-4551648|Reactome:R-HSA-3903017|Reactome:R-HSA-4570499|Reactome:R-HSA-4755526|Reactome:R-HSA-4755536|Reactome:R-HSA-4570493|Reactome:R-HSA-4615839|Reactome:R-HSA-4551721|Reactome:R-HSA-4085331|Reactome:R-HSA-4655431|Reactome:R-HSA-4570554|Reactome:R-HSA-8956365|Reactome:R-HSA-4341072|Reactome:R-HSA-4090288|Reactome:R-HSA-4551724|Reactome:R-HSA-4085318|Reactome:R-HSA-4641362|Reactome:R-HSA-3000433|Reactome:R-HSA-2997616|Reactome:R-HSA-3968414|Reactome:R-HSA-4615910|Reactome:R-HSA-4551738|Reactome:R-HSA-4085372|Reactome:R-HSA-2993769|Reactome:R-HSA-4085296|Reactome:R-HSA-4717521|Reactome:R-HSA-4341025|Reactome:R-HSA-3000434|Reactome:R-HSA-4719447|Reactome:R-HSA-2997723|Reactome:R-HSA-6804468|Reactome:R-HSA-6790454|Reactome:R-HSA-4568914|Reactome:R-HSA-4755411|Reactome:R-HSA-4615933|Reactome:R-HSA-6804485|Reactome:R-HSA-4655355|Reactome:R-HSA-4641342|Reactome:R-HSA-4090390|Reactome:R-HSA-3108209|Reactome:R-HSA-3247493|Reactome:R-HSA-3296126|Reactome:R-HSA-3927824|Reactome:R-HSA-3899291|Reactome:R-HSA-3000383|Reactome:R-HSA-4090281|Reactome:R-HSA-4570553|Reactome:R-HSA-4341073|Reactome:R-HSA-3234094|Reactome:R-HSA-4719448|Reactome:R-HSA-3465545|Reactome:R-HSA-4090408|Reactome:R-HSA-4616015|Reactome:R-HSA-3900194|Reactome:R-HSA-4755494|Reactome:R-HSA-3000449|Reactome:R-HSA-4570496|Reactome:R-HSA-4615987|Reactome:R-HSA-2997706|Reactome:R-HSA-4085992|Reactome:R-HSA-4720446|Reactome:R-HSA-4719423|Reactome:R-HSA-4719424|Reactome:R-HSA-3108212|Reactome:R-HSA-3234081|Reactome:R-HSA-4615900|Reactome:R-HSA-3234084|Reactome:R-HSA-4546387|Reactome:R-HSA-4615889|Reactome:R-HSA-4720432|Reactome:R-HSA-2997709|Reactome:R-HSA-5228508|Reactome:R-HSA-4085350|Reactome:R-HSA-5228523|Reactome:R-HSA-4551655|Reactome:R-HSA-4641350|Reactome:R-HSA-4755478|Reactome:R-HSA-4719436|Reactome:R-HSA-4086083|Reactome:R-HSA-4655374|Reactome:R-HSA-4551661|Reactome:R-HSA-4570463|Reactome:R-HSA-4551604|Reactome:R-HSA-3000399|Reactome:R-HSA-3927886|Reactome:R-HSA-5228521|Reactome:R-HSA-4551727|Reactome:R-HSA-4717461|Reactome:R-HSA-4615873|Reactome:R-HSA-4570489|Reactome:R-HSA-4546386|Reactome:R-HSA-4085347|Reactome:R-HSA-4568848|Reactome:R-HSA-3900177|Reactome:R-HSA-4551649|Reactome:R-HSA-4546385|Reactome:R-HSA-2993780|Reactome:R-HSA-4551679|Reactome:R-HSA-4656914|Reactome:R-HSA-4341048|Reactome:R-HSA-4615872|Reactome:R-HSA-4615905|Reactome:R-HSA-4090284|Reactome:R-HSA-4641345|Reactome:R-HSA-5682607|Reactome:R-HSA-3108203|Reactome:R-HSA-4341016|Reactome:R-HSA-3232162|Reactome:R-HSA-4086088|Reactome:R-HSA-4655440|Reactome:R-HSA-4085994|Reactome:R-HSA-2993790|Reactome:R-HSA-4086036|Reactome:R-HSA-4570467							GO:0019949|GO:0016930		molecular_function											owl:Class	
GO:0070371	biolink:NamedThing	ERK1 and ERK2 cascade	An intracellular protein kinase cascade containing at least ERK1 or ERK2 (MAPKs), a MEK (a MAPKK) and a MAP3K. The cascade may involve 4 different kinases, as it can also contain an additional tier: the upstream MAP4K. The kinases in each tier phosphorylate and activate the kinase in the downstream tier to transmit a signal within a cell.	tmpzr1t_l9r_go_relaxed.owl	ERK1 cascade|MAPK1 cascade|extracellular signal-regulated kinase 1/2 cascade|extracellular signal-regulated kinase 1/2 (ERK1/2) cascade|ERK cascade|MAPK3 cascade|ERK1/2 cascade|ERK2 cascade|ERK1 and ERK2 signalling pathway|ERK1 and ERK2 signaling pathway					Note that this MAPKKK cascade is commonly referred to as the ERK pathway in the literature, but involves only ERK1 or ERK2 and should not be confused with cascades that involve other ERK kinases.								biological_process											owl:Class	
GO:0000165	biolink:NamedThing	MAPK cascade	An intracellular protein kinase cascade containing at least a MAPK, a MAPKK and a MAP3K. The cascade can also contain an additional tiers: the upstream MAP4K. The kinases in each tier phosphorylate and activate the kinase in the downstream tier to transmit a signal within a cell.	tmpzr1t_l9r_go_relaxed.owl	MAPK signaling|MAP kinase kinase kinase cascade|MAPK signal transduction|MAPK signalling|mitogen-activated protein kinase cascade|MAPKKK cascade|MAPKKK cascade during sporulation|MAP kinase cascade|ERK/MAPK cascade				Wikipedia:Mitogen-activated_protein_kinase|Wikipedia:MAPK_cascade	MAPK cascades lie downstream of many cell surface receptors and cooperate in transmitting various extracellular signals to the nucleus. One way by which the specificity of each cascade is regulated is through the existence of several distinct components in each tier of the different cascades. The cascades are typically named according to the component in the MAPK tier.						GO:0007255		biological_process											owl:Class	
GO:0019334	biolink:NamedThing	p-cymene catabolic process	The chemical reactions and pathways resulting in the breakdown of p-cymene, 1-methyl-4-isopropylbenzene, one of the alkyl-substituted aromatic hydrocarbons found in volatile oils from over 100 plants.	tmpzr1t_l9r_go_relaxed.owl	p-cymene catabolism|p-cymene degradation|p-cymene breakdown				MetaCyc:PWY-741									biological_process											owl:Class	
GO:0043694	biolink:NamedThing	monoterpene catabolic process	The chemical reactions and pathways resulting in the breakdown of monoterpenes, terpenes with a C10 structure.	tmpzr1t_l9r_go_relaxed.owl	monoterpene catabolism													biological_process											owl:Class	
GO:0003963	biolink:NamedThing	RNA-3'-phosphate cyclase activity	Catalysis of the reaction: ATP + RNA 3'-terminal-phosphate = AMP + diphosphate + RNA terminal-2',3'-cyclic-phosphate.	tmpzr1t_l9r_go_relaxed.owl	RNA-3'-phosphate:RNA ligase (cyclizing, AMP-forming)|RNA 3'-terminal phosphate cyclase activity|RNA cyclase activity				RHEA:23976|EC:6.5.1.4|MetaCyc:RNA-3-PHOSPHATE-CYCLASE-RXN									molecular_function											owl:Class	
GO:0140098	biolink:NamedThing	catalytic activity, acting on RNA	Catalytic activity that acts to modify RNA, driven by ATP hydrolysis.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/14225|https://github.com/geneontology/go-ontology/issues/21612						pg	2017-09-14T12:05:21Z					molecular_function											owl:Class	
GO:0060759	biolink:NamedThing	regulation of response to cytokine stimulus	Any process that modulates the rate, frequency, or extent of a response to cytokine stimulus.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-06-22T02:56:12Z					biological_process											owl:Class	
GO:0015276	biolink:NamedThing	ligand-gated ion channel activity	Enables the transmembrane transfer of an ion by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts.	tmpzr1t_l9r_go_relaxed.owl	ionotropic receptor activity				Reactome:R-HSA-451310|Reactome:R-HSA-451311|Reactome:R-HSA-622326|Reactome:R-HSA-622325|Reactome:R-HSA-629595									molecular_function											owl:Class	
GO:0005216	biolink:NamedThing	ion channel activity	Enables the facilitated diffusion of an ion (by an energy-independent process) by passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism. May be either selective (it enables passage of a specific ion only) or non-selective (it enables passage of two or more ions of same charge but different size).	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0043448	biolink:NamedThing	alkane catabolic process	The chemical reactions and pathways resulting in the breakdown of an alkane, any acyclic branched or unbranched hydrocarbon having the general formula CnH2n+2.	tmpzr1t_l9r_go_relaxed.owl	alkane catabolism|alkane breakdown|alkane degradation													biological_process											owl:Class	
GO:0044248	biolink:NamedThing	cellular catabolic process	The chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells.	tmpzr1t_l9r_go_relaxed.owl	cellular catabolism|cellular breakdown|cellular degradation													biological_process											owl:Class	
GO:0102559	biolink:NamedThing	protein-(glutamine-N5) methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine  + a [release factor]-L-glutamine = S-adenosyl-L-homocysteine  + H+ + a [release factor]-N5-methyl-L-glutamine.	tmpzr1t_l9r_go_relaxed.owl					EC:2.1.1.297|MetaCyc:RXN-14992|RHEA:42896									molecular_function											owl:Class	
GO:1900156	biolink:NamedThing	positive regulation of bone trabecula formation	Any process that activates or increases the frequency, rate or extent of bone trabecula formation.	tmpzr1t_l9r_go_relaxed.owl	up regulation of bone trabecula formation|upregulation of bone trabecula biogenesis|upregulation of bone trabeculation|activation of bone trabecula biogenesis|upregulation of skeletal trabeculation|activation of bone trabecula formation|up-regulation of skeletal trabecula formation|upregulation of bone trabecula formation|up-regulation of bone trabecula biogenesis|upregulation of skeletal trabecula formation|up-regulation of skeletal trabecula biogenesis|activation of skeletal trabecula formation|positive regulation of skeletal trabecula formation|positive regulation of skeletal trabeculation|up regulation of skeletal trabecula formation|activation of skeletal trabecula biogenesis|positive regulation of bone trabecula biogenesis|positive regulation of skeletal trabecula biogenesis|up regulation of bone trabeculation|up-regulation of skeletal trabeculation|activation of skeletal trabeculation|up-regulation of bone trabeculation|upregulation of skeletal trabecula biogenesis|up regulation of bone trabecula biogenesis|up regulation of skeletal trabecula biogenesis|positive regulation of bone trabeculation|up regulation of skeletal trabeculation|up-regulation of bone trabecula formation|activation of bone trabeculation							vk	2012-03-07T01:47:10Z					biological_process											owl:Class	
GO:0060971	biolink:NamedThing	embryonic heart tube left/right pattern formation	The pattern specification process that results in the subdivision of the left/right axis of the embryonic heart tube in space to define an area or volume in which specific patterns of cell differentiation will take place.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-10-06T10:22:11Z					biological_process											owl:Class	
GO:0060972	biolink:NamedThing	left/right pattern formation	The pattern specification process that results in the subdivision of the left/right axis in space to define an area or volume in which specific patterns of cell differentiation will take place or in which cells interpret a specific environment.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-10-06T10:25:58Z					biological_process											owl:Class	
GO:0060787	biolink:NamedThing	positive regulation of posterior neural plate formation by fibroblast growth factor receptor signaling pathway	Any process that increases the rate or extent of the formation of the posterior neural plate, the posterior end of the flat, thickened layer of ectodermal cells known as the neural plate.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of posterior neural plate formation by fibroblast growth factor receptor signalling pathway|positive regulation of posterior neural plate formation by FGF receptor signaling pathway							dph	2009-08-04T09:48:31Z					biological_process											owl:Class	
GO:0045995	biolink:NamedThing	regulation of embryonic development	Any process that modulates the frequency, rate or extent of embryonic development.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0097325	biolink:NamedThing	melanocyte proliferation	The multiplication or reproduction of melanocytes, resulting in the expansion of a cell population. A melanocyte is a pigment cell derived from the neural crest. It contains melanin-filled pigment granules, which give a brown to black appearance.	tmpzr1t_l9r_go_relaxed.owl								pr	2012-06-08T10:10:12Z					biological_process											owl:Class	
GO:0050673	biolink:NamedThing	epithelial cell proliferation	The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population. Epithelial cells make up the epithelium, the covering of internal and external surfaces of the body, including the lining of vessels and other small cavities. It consists of cells joined by small amounts of cementing substances.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1902935	biolink:NamedThing	protein localization to septin ring	A process in which a protein is transported to, or maintained in, a location within a septin ring.	tmpzr1t_l9r_go_relaxed.owl	protein localisation in septin ring|protein localization in septin ring|protein localisation to septin ring							mah	2014-04-25T13:08:17Z					biological_process											owl:Class	
GO:0044380	biolink:NamedThing	protein localization to cytoskeleton	A process in which a protein is transported to, or maintained in, a location within the cytoskeleton.	tmpzr1t_l9r_go_relaxed.owl	protein localisation to cytoskeleton							jl	2011-12-13T11:43:24Z					biological_process											owl:Class	
GO:2000808	biolink:NamedThing	negative regulation of synaptic vesicle clustering	Any process that stops, prevents or reduces the frequency, rate or extent of synaptic vesicle clustering.	tmpzr1t_l9r_go_relaxed.owl								pr	2011-07-06T09:50:34Z					biological_process											owl:Class	
GO:2000807	biolink:NamedThing	regulation of synaptic vesicle clustering	Any process that modulates the frequency, rate or extent of synaptic vesicle clustering.	tmpzr1t_l9r_go_relaxed.owl								pr	2011-07-06T09:50:30Z					biological_process											owl:Class	
GO:1903500	biolink:NamedThing	negative regulation of mitotic actomyosin contractile ring assembly	Any process that stops, prevents or reduces the frequency, rate or extent of mitotic actomyosin contractile ring assembly.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of actomyosin contractile ring assembly involved in cytokinesis after mitosis|downregulation of mitotic actomyosin contractile ring assembly|down-regulation of contractile ring assembly involved in mitotic cytokinesis|downregulation of cytokinesis, actomyosin contractile ring assembly involved in mitotic cytokinesis|down regulation of mitotic actomyosin contractile ring assembly|inhibition of cytokinesis, actomyosin contractile ring assembly involved in mitotic cytokinesis|down regulation of cytokinesis, actomyosin contractile ring assembly involved in mitotic cytokinesis|inhibition of mitotic actomyosin contractile ring assembly|negative regulation of contractile ring assembly involved in mitotic cytokinesis|down regulation of contractile ring assembly involved in mitotic cytokinesis|inhibition of contractile ring assembly involved in mitotic cytokinesis|downregulation of actomyosin contractile ring assembly involved in cytokinesis after mitosis|negative regulation of mitotic cytokinesis, actomyosin contractile ring assembly|down-regulation of cytokinesis, actomyosin contractile ring assembly involved in mitotic cytokinesis|downregulation of contractile ring assembly involved in mitotic cytokinesis|negative regulation of cytokinesis, actomyosin contractile ring assembly involved in mitotic cytokinesis|down-regulation of mitotic actomyosin contractile ring assembly|inhibition of actomyosin contractile ring assembly involved in cytokinesis after mitosis|down regulation of actomyosin contractile ring assembly involved in cytokinesis after mitosis|down-regulation of actomyosin contractile ring assembly involved in cytokinesis after mitosis							pr	2014-09-30T10:13:59Z					biological_process											owl:Class	
GO:2000432	biolink:NamedThing	negative regulation of cytokinesis, actomyosin contractile ring assembly	Any process that stops, prevents or reduces the frequency, rate or extent of cytokinesis, actomyosin contractile ring assembly.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of contractile ring assembly							vw	2011-03-03T12:18:16Z					biological_process											owl:Class	
GO:0060874	biolink:NamedThing	posterior semicircular canal development	The progession of the posterior semicircular canal from its initial formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-08-13T09:42:39Z					biological_process											owl:Class	
GO:0060872	biolink:NamedThing	semicircular canal development	The progression of the semicircular canal from its initial formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-08-13T09:36:37Z					biological_process											owl:Class	
GO:1905487	biolink:NamedThing	negative regulation of anterior/posterior axon guidance	Any process that stops, prevents or reduces the frequency, rate or extent of anterior/posterior axon guidance.	tmpzr1t_l9r_go_relaxed.owl	inhibition of anterior/posterior axon pathfinding|downregulation of anterior/posterior axon pathfinding|downregulation of anterior-posterior axon guidance|down-regulation of anterior-posterior axon guidance|down regulation of anterior-posterior axon guidance|inhibition of anterior-posterior axon guidance|inhibition of anterior/posterior axon guidance|negative regulation of anterior/posterior axon pathfinding|downregulation of anterior/posterior axon guidance|down-regulation of anterior/posterior axon guidance|down-regulation of anterior/posterior axon pathfinding|negative regulation of anterior-posterior axon guidance|down regulation of anterior/posterior axon pathfinding|down regulation of anterior/posterior axon guidance							hbye	2016-09-23T13:18:41Z					biological_process											owl:Class	
GO:1905486	biolink:NamedThing	regulation of anterior/posterior axon guidance	Any process that modulates the frequency, rate or extent of anterior/posterior axon guidance.	tmpzr1t_l9r_go_relaxed.owl	regulation of anterior-posterior axon guidance|regulation of anterior/posterior axon pathfinding							hbye	2016-09-23T13:18:33Z					biological_process											owl:Class	
GO:1905297	biolink:NamedThing	positive regulation of neural crest cell fate specification	Any process that activates or increases the frequency, rate or extent of neural crest cell fate specification.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of neural crest cell fate specification|activation of neural crest cell fate specification|upregulation of neural crest cell fate specification|up regulation of neural crest cell fate specification							rl	2016-06-28T15:14:57Z					biological_process											owl:Class	
GO:0090300	biolink:NamedThing	positive regulation of neural crest formation	Any process that increases the rate, frequency, or extent of neural crest formation. Neural crest formation is the formation of the specialized region of ectoderm between the neural ectoderm (neural plate) and non-neural ectoderm. The neural crest gives rise to the neural crest cells that migrate away from this region as neural tube formation procedes.	tmpzr1t_l9r_go_relaxed.owl								tb	2010-03-12T04:08:26Z					biological_process											owl:Class	
GO:0150128	biolink:NamedThing	negative regulation of interleukin-33 production	Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-33 production.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of interleukin-33 biosynthetic process|negative regulation of interleukin-33 secretion							bc	2019-12-03T05:54:24Z			GO:0150131|GO:0150124		biological_process											owl:Class	
GO:0034638	biolink:NamedThing	phosphatidylcholine catabolic process	The chemical reactions and pathways resulting in the breakdown of phosphatidylcholines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of choline.	tmpzr1t_l9r_go_relaxed.owl	phosphatidylcholine breakdown|phosphatidylcholine degradation|phosphatidylcholine catabolism													biological_process											owl:Class	
GO:0035311	biolink:NamedThing	wing cell fate specification	The process in which a cell in the larval wing imaginal disc becomes capable of differentiating autonomously into a wing cell, if left in its normal environment.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1905010	biolink:NamedThing	positive regulation of L-lysine import across plasma membrane	Any process that activates or increases the frequency, rate or extent of L-lysine import into cell.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of L-lysine import into cell|up regulation of L-lysine import into cell|up-regulation of L-lysine import into cell|activation of L-lysine import into cell|upregulation of L-lysine import into cell							sl	2016-03-02T00:16:04Z					biological_process											owl:Class	
GO:1903961	biolink:NamedThing	positive regulation of anion transmembrane transport	Any process that activates or increases the frequency, rate or extent of anion transmembrane transport.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of anion transmembrane transport|upregulation of anion transmembrane transport|up regulation of anion transmembrane transport|activation of anion transmembrane transport							pr	2015-02-25T13:52:44Z					biological_process											owl:Class	
GO:2000401	biolink:NamedThing	regulation of lymphocyte migration	Any process that modulates the frequency, rate or extent of lymphocyte migration.	tmpzr1t_l9r_go_relaxed.owl								mah	2011-02-23T10:45:19Z					biological_process											owl:Class	
GO:0045543	biolink:NamedThing	gibberellin 2-beta-dioxygenase activity	Catalysis of the reaction: a gibberellin + 2-oxoglutarate + O2 = a 2-beta-hydroxygibberellin + succinate + CO2.	tmpzr1t_l9r_go_relaxed.owl	gibberellin 2-beta-hydroxylase activity|gibberellin 2beta-hydroxylase activity|gibberellin 2beta-dioxygenase activity|gibberellin 2-oxidase activity|(gibberellin-1),2-oxoglutarate:oxygen oxidoreductase (2beta-hydroxylating)				MetaCyc:PWY-102|RHEA:15005|EC:1.14.11.13									molecular_function											owl:Class	
GO:1901484	biolink:NamedThing	negative regulation of transcription factor catabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of transcription factor catabolic process.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of sequence-specific DNA binding transcription factor catabolic process|down regulation of transcription factor degradation|downregulation of proteasome-mediated transcription factor catabolism|downregulation of transcription factor catabolic process|negative regulation of proteasome-mediated transcription factor catabolism|down regulation of sequence-specific DNA binding transcription factor catabolic process|down-regulation of transcription factor degradation|down regulation of proteasome-mediated transcription factor catabolism|inhibition of transcription factor catabolism|downregulation of transcription factor degradation|downregulation of transcription factor catabolism|down regulation of transcription factor catabolism|down-regulation of transcription factor catabolic process|inhibition of proteasome-mediated transcription factor catabolism|down-regulation of proteasome-mediated transcription factor catabolism|negative regulation of sequence-specific DNA binding transcription factor catabolic process|inhibition of transcription factor breakdown|down regulation of transcription factor breakdown|inhibition of sequence-specific DNA binding transcription factor catabolic process|negative regulation of transcription factor breakdown|down-regulation of transcription factor breakdown|negative regulation of transcription factor catabolism|inhibition of transcription factor catabolic process|negative regulation of transcription factor degradation|downregulation of transcription factor breakdown|downregulation of sequence-specific DNA binding transcription factor catabolic process|inhibition of transcription factor degradation|down-regulation of transcription factor catabolism|down regulation of transcription factor catabolic process							bf	2012-10-08T09:03:22Z					biological_process											owl:Class	
GO:0030081	biolink:NamedThing	B800-820 antenna complex	Protein-pigment complex that absorbs light at 800 and 820 nm; is peripherally associated to the bacterial reaction center; transfers excitation energy to the B875 antenna complex.	tmpzr1t_l9r_go_relaxed.owl	light harvesting complex III|LH3 complex													cellular_component											owl:Class	
GO:0034843	biolink:NamedThing	2-oxoglutaryl-CoA thioesterase activity	Catalysis of the reaction: 2-oxoglutaryl-CoA + OH- = 2-oxoglutarate + CoASH.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r1238									molecular_function											owl:Class	
GO:0016790	biolink:NamedThing	thiolester hydrolase activity	Catalysis of the reaction: RCO-SR' + H2O = RCOOH + HSR'. This reaction is the hydrolysis of a thiolester bond, an ester formed from a carboxylic acid and a thiol (i.e., RCO-SR'), such as that found in acetyl-coenzyme A.	tmpzr1t_l9r_go_relaxed.owl	thiolesterase activity				EC:3.1.2.-									molecular_function											owl:Class	
GO:0097082	biolink:NamedThing	vascular associated smooth muscle cell fate specification	The process in which a cell becomes capable of differentiating autonomously into a vascular smooth muscle cell in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed. A vascular smooth muscle cell is a non-striated, elongated, spindle-shaped cell found lining the blood vessels.	tmpzr1t_l9r_go_relaxed.owl	vascular smooth muscle cell fate specification							pr	2011-06-20T03:56:21Z					biological_process											owl:Class	
GO:0042694	biolink:NamedThing	muscle cell fate specification	The process in which a cell becomes capable of differentiating autonomously into a muscle cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0070009	biolink:NamedThing	serine-type aminopeptidase activity	Catalysis of the hydrolysis of a single N-terminal amino acid residue from a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine).	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/19681												molecular_function											owl:Class	
GO:0070008	biolink:NamedThing	serine-type exopeptidase activity	Catalysis of the hydrolysis of a peptide bond not more than three residues from the N- or C-terminus of a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine).	tmpzr1t_l9r_go_relaxed.owl					EC:3.4.21.-									molecular_function											owl:Class	
GO:0005942	biolink:NamedThing	phosphatidylinositol 3-kinase complex	A protein complex capable of phosphatidylinositol 3-kinase activity and containing subunits of any phosphatidylinositol 3-kinase (PI3K) enzyme. These complexes are divided in three classes (called I, II and III) that differ for their presence across taxonomic groups and for the type of their constituents. Catalytic subunits of phosphatidylinositol 3-kinase enzymes are present in all 3 classes; regulatory subunits of phosphatidylinositol 3-kinase enzymes are present in classes I and III; adaptor proteins have been observed in class II complexes and may be present in other classes too.	tmpzr1t_l9r_go_relaxed.owl	phosphoinositide 3-kinase complex|PIK3C3-PIK3R4 complex|PI3K complex|PI3-kinase p85-subunit alpha- PI3-kinase p110 complex|PIK3CA-PIK3R1 complex|1-phosphatidylinositol 3-kinase complex					For discussion of membrane association, please see https://sourceforge.net/p/geneontology/ontology-requests/11559/								cellular_component											owl:Class	
GO:0044192	biolink:NamedThing	host cell mitochondrial inner membrane	The inner, i.e. lumen-facing, lipid bilayer of the host cell mitochondrial envelope. It is highly folded to form cristae.	tmpzr1t_l9r_go_relaxed.owl								jl	2009-10-15T04:17:29Z					cellular_component											owl:Class	
GO:0044191	biolink:NamedThing	host cell mitochondrial membrane	Either of the lipid bilayers that surround the host cell mitochondrion and form the host cell mitochondrial envelope.	tmpzr1t_l9r_go_relaxed.owl								jl	2009-10-15T04:14:35Z					cellular_component											owl:Class	
GO:0045680	biolink:NamedThing	negative regulation of R8 cell differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of R8 cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	down regulation of R8 differentiation|negative regulation of R8 differentiation|downregulation of R8 differentiation|inhibition of R8 differentiation|down-regulation of R8 differentiation													biological_process											owl:Class	
GO:0110118	biolink:NamedThing	negative regulation of compound eye photoreceptor cell differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of compound eye photoreceptor cell differentiation.	tmpzr1t_l9r_go_relaxed.owl								kmv	2018-07-16T18:15:52Z					biological_process											owl:Class	
GO:0060504	biolink:NamedThing	positive regulation of epithelial cell proliferation involved in lung bud dilation	Any process that increases the rate or frequency of epithelial cell proliferation that results in the lung bud increasing in size radially.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0048639	biolink:NamedThing	positive regulation of developmental growth	Any process that activates, maintains or increases the rate of developmental growth.	tmpzr1t_l9r_go_relaxed.owl	up regulation of developmental growth|upregulation of developmental growth|activation of developmental growth|stimulation of developmental growth|up-regulation of developmental growth													biological_process											owl:Class	
GO:0009398	biolink:NamedThing	FMN biosynthetic process	The chemical reactions and pathways resulting in the formation of FMN, the oxidized form of flavin mononucleotide (riboflavin 5'-(dihydrogen phosphate)), which acts as a coenzyme for a number of oxidative enzymes including NADH dehydrogenase.	tmpzr1t_l9r_go_relaxed.owl	FMN biosynthesis|FMN anabolism|FMN formation|FMN synthesis													biological_process											owl:Class	
GO:0009156	biolink:NamedThing	ribonucleoside monophosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of a ribonucleoside monophosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with phosphate on the sugar.	tmpzr1t_l9r_go_relaxed.owl	ribonucleoside monophosphate synthesis|ribonucleoside monophosphate biosynthesis|ribonucleoside monophosphate formation|ribonucleoside monophosphate anabolism													biological_process											owl:Class	
GO:0002127	biolink:NamedThing	tRNA wobble base cytosine methylation	The process in which the base of cytosine at position 34 in the anticodon of a tRNA is post-transcriptionally methylated at the C5 position.	tmpzr1t_l9r_go_relaxed.owl	wobble position m5C biosynthesis													biological_process											owl:Class	
GO:0002101	biolink:NamedThing	tRNA wobble cytosine modification	The process in which a cytosine in position 34 of a tRNA is post-transcriptionally modified.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1990058	biolink:NamedThing	fruit replum development	The process whose specific outcome is the progression of the fruit replum over time, from its formation to the mature structure. The fruit replum is a portion of fruit placenta tissue that divides a fruit into two or more chambers and develops from a replum.	tmpzr1t_l9r_go_relaxed.owl								dhl	2013-03-12T21:15:15Z					biological_process											owl:Class	
GO:0002672	biolink:NamedThing	positive regulation of B cell anergy	Any process that activates or increases the frequency, rate, or extent of B cell anergy.	tmpzr1t_l9r_go_relaxed.owl	upregulation of B cell anergy|activation of B cell anergy|up-regulation of B cell anergy|stimulation of B cell anergy|positive regulation of B-cell anergy|positive regulation of B-lymphocyte anergy|up regulation of B cell anergy|positive regulation of B lymphocyte anergy													biological_process											owl:Class	
GO:0002663	biolink:NamedThing	positive regulation of B cell tolerance induction	Any process that activates or increases the frequency, rate, or extent of B cell tolerance induction.	tmpzr1t_l9r_go_relaxed.owl	activation of B cell tolerance induction|stimulation of B cell tolerance induction|upregulation of B cell tolerance induction|up-regulation of B cell tolerance induction|positive regulation of B-lymphocyte tolerance induction|positive regulation of B-cell tolerance induction|up regulation of B cell tolerance induction|positive regulation of B lymphocyte tolerance induction													biological_process											owl:Class	
GO:1903560	biolink:NamedThing	3-cyano-L-alanine biosynthetic process	The chemical reactions and pathways resulting in the formation of 3-cyano-L-alanine.	tmpzr1t_l9r_go_relaxed.owl	3-cyano-L-alanine biosynthesis|3-cyano-L-alanine anabolism|3-cyano-L-alanine formation|3-cyano-L-alanine synthesis							kmv	2014-10-21T17:13:26Z					biological_process											owl:Class	
GO:1903558	biolink:NamedThing	3-cyano-L-alanine metabolic process	The chemical reactions and pathways involving 3-cyano-L-alanine.	tmpzr1t_l9r_go_relaxed.owl	3-cyano-L-alanine metabolism							kmv	2014-10-21T17:13:00Z					biological_process											owl:Class	
GO:0120316	biolink:NamedThing	sperm flagellum assembly	The assembly and organization of the sperm flagellum, the microtubule-based axoneme and associated structures that are part of a sperm flagellum (or cilium).	tmpzr1t_l9r_go_relaxed.owl								krc	2021-04-29T01:27:27Z					biological_process											owl:Class	
GO:0032601	biolink:NamedThing	connective tissue growth factor production	The appearance of connective tissue growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	tmpzr1t_l9r_go_relaxed.owl	CTGF production|Fisp12 production|Hcs24 production|IGFBP8 production|CCN2 production|hypertrophic chondrocyte-specific gene product 24 production													biological_process											owl:Class	
GO:0005313	biolink:NamedThing	L-glutamate transmembrane transporter activity	Enables the transfer of L-glutamate from one side of a membrane to the other. L-glutamate is the anion of 2-aminopentanedioic acid.	tmpzr1t_l9r_go_relaxed.owl	L-glutamate transporter activity|glutamate/aspartate porter activity|glutamate/aspartate:sodium symporter activity				Reactome:R-HSA-5624256|Reactome:R-HSA-428052|Reactome:R-HSA-210444									molecular_function											owl:Class	
GO:2000607	biolink:NamedThing	negative regulation of cell proliferation involved in mesonephros development	Any process that stops, prevents or reduces the frequency, rate or extent of cell proliferation involved in mesonephros development.	tmpzr1t_l9r_go_relaxed.owl								yaf	2011-04-18T08:42:23Z					biological_process											owl:Class	
GO:1901723	biolink:NamedThing	negative regulation of cell proliferation involved in kidney development	Any process that stops, prevents or reduces the frequency, rate or extent of cell proliferation involved in kidney development.	tmpzr1t_l9r_go_relaxed.owl	down regulation of cell proliferation involved in kidney development|down-regulation of cell proliferation involved in kidney development|inhibition of cell proliferation involved in kidney development|downregulation of cell proliferation involved in kidney development							krc	2012-12-27T19:30:35Z					biological_process											owl:Class	
GO:0097586	biolink:NamedThing	dolichyl-phosphate-mannose-protein mannosyltransferase Pmt4p homodimer complex	A protein dimer complex that possesses dolichyl-phosphate-mannose-protein mannosyltransferase activity and, in S. cerevisiae, is composed of Pmt4p.	tmpzr1t_l9r_go_relaxed.owl	dolichyl-phosphate-mannose-protein mannosyltransferase Pmt4p-Pmt4p dimer complex|Pmt4p-Pmt4p complex|dolichyl-phosphate-mannose-protein mannosyltransferase Pmt4p dimer							pr	2014-03-02T18:19:05Z					cellular_component											owl:Class	
GO:0031502	biolink:NamedThing	dolichyl-phosphate-mannose-protein mannosyltransferase complex	A complex that possesses dolichyl-phosphate-mannose-protein mannosyltransferase activity; usually includes members of the PMT1 and PMT2 protein subfamilies.	tmpzr1t_l9r_go_relaxed.owl	protein O-mannosyltransferase complex|PMT family mannosyltransferase complex					Note that GO:0004169 'dolichyl-phosphate-mannose-protein mannosyltransferase activity' (part of protein O-linked mannosylation) has never been observed in green plants. However, N- and C-mannosylation may occur in these species; see figure 1 in PMID:21558543.								cellular_component											owl:Class	
GO:0006591	biolink:NamedThing	ornithine metabolic process	The chemical reactions and pathways involving ornithine, an amino acid only rarely found in proteins, but which is important in living organisms as an intermediate in the reactions of the urea cycle and in arginine biosynthesis.	tmpzr1t_l9r_go_relaxed.owl	ornithine metabolism													biological_process											owl:Class	
GO:0016133	biolink:NamedThing	brassinosteroid catabolic process	The chemical reactions and pathways resulting in the breakdown of brassinosteroids, any of a group of steroid derivatives that occur at very low concentrations in plant tissues and may have hormone-like effects.	tmpzr1t_l9r_go_relaxed.owl	brassinosteroid catabolism|brassinosteroid degradation|brassinosteroid breakdown													biological_process											owl:Class	
GO:0016130	biolink:NamedThing	phytosteroid catabolic process	The chemical reactions and pathways resulting in the breakdown of phytosteroids, steroids that differ from animal steroids in having substitutions at C24 and/or a double bond at C22. Phytosteroids are so named because they occur in higher plants; some, notably ergosterol, are also found in fungi.	tmpzr1t_l9r_go_relaxed.owl	phytosteroid degradation|phytosteroid breakdown|phytosteroid catabolism													biological_process											owl:Class	
GO:0061586	biolink:NamedThing	positive regulation of transcription by transcription factor localization	Any process that activates or increases the frequency, rate or extent of DNA-dependent transcription using a mechanism that involves the localization of a transcription factor.	tmpzr1t_l9r_go_relaxed.owl								dph	2014-01-31T08:43:43Z					biological_process											owl:Class	
GO:1990321	biolink:NamedThing	collagen type XXII trimer	A collagen homotrimer of alpha1(XXII) chains; type XXII collagen triple helices acts as a cell adhesion ligand for skin epithelial cells and fibroblasts.	tmpzr1t_l9r_go_relaxed.owl								bhm	2014-03-14T16:50:05Z					cellular_component											owl:Class	
GO:0005593	biolink:NamedThing	FACIT collagen trimer	A collagen trimer that associates with collagen fibrils and consists of collagen monomers that contain two or more relatively short triple-helical domains connected by non-triple-helical sequences.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:FACIT_collagen	The acronym FACIT stands for fibril-associated collagen with interrupted triple helix.								cellular_component											owl:Class	
GO:1903332	biolink:NamedThing	regulation of protein folding	Any process that modulates the frequency, rate or extent of protein folding.	tmpzr1t_l9r_go_relaxed.owl	regulation of chaperonin-mediated tubulin folding|regulation of co-chaperone activity|regulation of protein complex assembly, multichaperone pathway|regulation of co-chaperonin activity|regulation of chaperone activity|regulation of alpha-tubulin folding|regulation of beta-tubulin folding|regulation of glycoprotein-specific chaperone activity|regulation of non-chaperonin molecular chaperone ATPase activity|regulation of chaperonin ATPase activity							vw	2014-08-18T13:14:34Z					biological_process											owl:Class	
GO:1902843	biolink:NamedThing	positive regulation of netrin-activated signaling pathway	Any process that activates or increases the frequency, rate or extent of netrin-activated signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of netrin-activated signalling pathway|up-regulation of netrin-mediated signaling pathway|activation of netrin-mediated signaling pathway|up-regulation of netrin-activated signal transduction pathway|up-regulation of netrin-activated signalling pathway|up regulation of netrin signaling pathway|up-regulation of netrin-activated signaling pathway|upregulation of netrin-mediated signaling pathway|up regulation of netrin-mediated signaling pathway|upregulation of netrin-activated signalling pathway|upregulation of netrin-activated signaling pathway|activation of netrin-activated signalling pathway|up regulation of netrin-activated signaling pathway|activation of netrin-activated signal transduction pathway|positive regulation of netrin signaling pathway|activation of netrin signaling pathway|positive regulation of netrin-mediated signaling pathway|upregulation of netrin-activated signal transduction pathway|up-regulation of netrin signaling pathway|up regulation of netrin-activated signalling pathway|up regulation of netrin-activated signal transduction pathway|upregulation of netrin signaling pathway|activation of netrin-activated signaling pathway|positive regulation of netrin-activated signal transduction pathway							kmv	2014-04-01T15:25:53Z					biological_process											owl:Class	
GO:0036040	biolink:NamedThing	curcumin catabolic process	The chemical reactions and pathways resulting in the breakdown of the polyphenol, curcumin.	tmpzr1t_l9r_go_relaxed.owl	(1E,6E)-1,7-bis(4-hydroxy-3-methoxyphenyl)hepta-1,6-diene-3,5-dione catabolic process|turmeric yellow catabolism|diferuloylmethane catabolism|diferuloylmethane breakdown|turmeric yellow catabolic process|curcumin breakdown|diferuloylmethane catabolic process|turmeric yellow breakdown|(1E,6E)-1,7-bis(4-hydroxy-3-methoxyphenyl)hepta-1,6-diene-3,5-dione degradation|curcumin catabolism|turmeric yellow degradation|(1E,6E)-1,7-bis(4-hydroxy-3-methoxyphenyl)hepta-1,6-diene-3,5-dione catabolism|(1E,6E)-1,7-bis(4-hydroxy-3-methoxyphenyl)hepta-1,6-diene-3,5-dione breakdown|diferuloylmethane degradation|curcumin degradation							bf	2011-11-22T02:01:05Z					biological_process											owl:Class	
GO:0098943	biolink:NamedThing	neurotransmitter receptor transport, postsynaptic endosome to lysosome	The directed movement of neurotransmitter receptor from the postsynaptic endosome in tranpsort vesicles to the lysosome for degradation.	tmpzr1t_l9r_go_relaxed.owl	postsynaptic neurotransmitter receptor endosomal trafficking													biological_process											owl:Class	
GO:0061462	biolink:NamedThing	protein localization to lysosome	A process in which a protein is transported to, or maintained in, a location within a lysosome.	tmpzr1t_l9r_go_relaxed.owl								dph	2012-10-05T10:50:51Z					biological_process											owl:Class	
GO:0003205	biolink:NamedThing	cardiac chamber development	The progression of a cardiac chamber over time, from its formation to the mature structure. A cardiac chamber is an enclosed cavity within the heart.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-10-13T09:11:18Z					biological_process											owl:Class	
GO:0045832	biolink:NamedThing	positive regulation of light-activated channel activity	Any process that activates or increases the frequency, rate or extent of light-activated channel activity.	tmpzr1t_l9r_go_relaxed.owl	activation of light-activated channel activity|up regulation of light-activated channel activity|upregulation of light-activated channel activity|up-regulation of light-activated channel activity|stimulation of light-activated channel activity													biological_process											owl:Class	
GO:0016061	biolink:NamedThing	regulation of light-activated channel activity	Any process that modulates the frequency, rate or extent of light-activated channel activity.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0050879	biolink:NamedThing	multicellular organismal movement	Any physiological process involved in changing the position of a multicellular organism or an anatomical part of a multicellular organism.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1902073	biolink:NamedThing	positive regulation of hypoxia-inducible factor-1alpha signaling pathway	Any process that activates or increases the frequency, rate or extent of hypoxia-inducible factor-1alpha signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	up regulation of hypoxia-inducible factor-1alpha signalling pathway|activation of hypoxia-inducible factor-1alpha signaling pathway|up-regulation of HIF1alpha pathway|upregulation of hypoxia-inducible factor-1alpha signalling pathway|activation of HIF1alpha pathway|activation of hypoxia-inducible factor-1alpha signalling pathway|hypoxic stabilization of HIF1A|up regulation of hypoxia-inducible factor-1alpha signaling pathway|positive regulation of HIF1alpha pathway|upregulation of hypoxia-inducible factor-1alpha signaling pathway|up regulation of HIF1alpha pathway|up-regulation of hypoxia-inducible factor-1alpha signalling pathway|up-regulation of hypoxia-inducible factor-1alpha signaling pathway|upregulation of HIF1alpha pathway|positive regulation of hypoxia-inducible factor-1alpha signalling pathway							bf	2013-04-18T13:28:30Z					biological_process											owl:Class	
GO:1902071	biolink:NamedThing	regulation of hypoxia-inducible factor-1alpha signaling pathway	Any process that modulates the frequency, rate or extent of hypoxia-inducible factor-1alpha signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	regulation of hypoxia-inducible factor-1alpha signalling pathway|regulation of HIF1alpha pathway							bf	2013-04-18T13:28:21Z					biological_process											owl:Class	
GO:0032078	biolink:NamedThing	negative regulation of endodeoxyribonuclease activity	Any process that stops or reduces the rate of endodeoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid by creating internal breaks.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of endodeoxyribonuclease activity|downregulation of endodeoxyribonuclease activity|down regulation of endodeoxyribonuclease activity|inhibition of endodeoxyribonuclease activity|endodeoxyribonuclease inhibitor													biological_process											owl:Class	
GO:0032071	biolink:NamedThing	regulation of endodeoxyribonuclease activity	Any process that modulates the frequency, rate or extent of endodeoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid by creating internal breaks.	tmpzr1t_l9r_go_relaxed.owl	endodeoxyribonuclease regulator													biological_process											owl:Class	
GO:1901438	biolink:NamedThing	negative regulation of toluene metabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of toluene metabolic process.	tmpzr1t_l9r_go_relaxed.owl	downregulation of methylbenzene metabolic process|negative regulation of toluene metabolism|negative regulation of methylbenzene metabolism|down regulation of toluene metabolism|down-regulation of methylbenzene metabolism|down regulation of toluene metabolic process|downregulation of toluene metabolism|down regulation of methylbenzene metabolism|inhibition of toluene metabolism|inhibition of methylbenzene metabolic process|down-regulation of toluene metabolic process|inhibition of toluene metabolic process|down regulation of methylbenzene metabolic process|downregulation of toluene metabolic process|inhibition of methylbenzene metabolism|down-regulation of toluene metabolism|downregulation of methylbenzene metabolism|down-regulation of methylbenzene metabolic process|negative regulation of methylbenzene metabolic process							tt	2012-10-01T21:18:50Z					biological_process											owl:Class	
GO:0060694	biolink:NamedThing	regulation of cholesterol transporter activity	Any process that modulates the rate, frequency, or extent of cholesterol transporter activity.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-06-08T02:05:27Z					biological_process											owl:Class	
GO:0031381	biolink:NamedThing	viral RNA-directed RNA polymerase complex	A virus-specific protein complex that possesses RNA-dependent RNA polymerase activity and replicates the genome of an RNA virus.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:1903976	biolink:NamedThing	negative regulation of glial cell migration	Any process that stops, prevents or reduces the frequency, rate or extent of glial cell migration.	tmpzr1t_l9r_go_relaxed.owl	downregulation of glia cell migration|inhibition of glia cell migration|down regulation of glia cell migration|down-regulation of glial cell migration|down-regulation of glia cell migration|downregulation of glial cell migration|down regulation of glial cell migration|inhibition of glial cell migration|negative regulation of glia cell migration							nc	2015-03-02T15:13:38Z					biological_process											owl:Class	
GO:0030336	biolink:NamedThing	negative regulation of cell migration	Any process that stops, prevents, or reduces the frequency, rate or extent of cell migration.	tmpzr1t_l9r_go_relaxed.owl	down regulation of cell migration|down-regulation of cell migration|downregulation of cell migration|inhibition of cell migration													biological_process											owl:Class	
GO:0052041	biolink:NamedThing	negative regulation by symbiont of host programmed cell death	Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of programmed cell death in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	suppression by symbiont of host PCD|suppression by symbiont of host programmed cell death|inhibition of host programmed cell death|down-regulation by symbiont of host programmed cell death|inhibition by symbiont of host programmed cell death|down regulation by symbiont of host programmed cell death|downregulation by symbiont of host programmed cell death													biological_process											owl:Class	
GO:0044003	biolink:NamedThing	modulation by symbiont of host process	The process in which a symbiont organism effects a change in the structure or processes of its host organism.	tmpzr1t_l9r_go_relaxed.owl	modulation by symbiont of host system process|pathogenesis|disruption by symbiont of host cell|modification by symbiont of host morphology or physiology|regulation by symbiont of host system process|modification by symbiont of host biological process	https://github.com/geneontology/go-ontology/issues/18719										GO:0044055|GO:0044004		biological_process											owl:Class	
GO:0043482	biolink:NamedThing	cellular pigment accumulation	The aggregation of coloring matter in a particular location in a cell, occurring in response to some external stimulus.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0051716	biolink:NamedThing	cellular response to stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus by a cell and ends with a change in state or activity or the cell.	tmpzr1t_l9r_go_relaxed.owl						Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.								biological_process											owl:Class	
GO:0015104	biolink:NamedThing	antimonite transmembrane transporter activity	Enables the transfer of antimonite from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0043614	biolink:NamedThing	multi-eIF complex	A multifactor complex composed of multiple translation initiation factors and the initiatior tRNAiMet, which is ready to bind to the small (40S) ribosome to form the 43S preinitiation complex. In S. cerevisiae, this complex is composed of eIF1, eIF2, eIF3, and eIF5.	tmpzr1t_l9r_go_relaxed.owl	multifactor translation initiation factor (eIF) complex													cellular_component											owl:Class	
GO:0015638	biolink:NamedThing	microcin transmembrane transporter activity	Enables the transfer of a microcin from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	microcin uptake permease activity													molecular_function											owl:Class	
GO:0042910	biolink:NamedThing	xenobiotic transmembrane transporter activity	Enables the directed movement of a xenobiotic from one side of a membrane to the other. A xenobiotic is a compound foreign to the organim exposed to it. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical.	tmpzr1t_l9r_go_relaxed.owl	drug transporter activity|multidrug transporter activity|xenobiotic transporter activity|multidrug efflux pump activity|multidrug, alkane resistant pump activity|drug transmembrane transporter activity	https://github.com/geneontology/go-ontology/issues/19460										GO:0015564|GO:0015238|GO:0015559|GO:0090484|GO:0015239		molecular_function											owl:Class	
GO:0061111	biolink:NamedThing	epithelial-mesenchymal cell signaling involved in lung development	Any process that results in the transfer of information from an epithelial cell to a mesenchymal cell and contributes to the progression of the lung over time from its initial formation to the mature organ.	tmpzr1t_l9r_go_relaxed.owl	epithelial-mesenchymal cell signalling involved in lung development							dph	2010-05-05T11:14:38Z					biological_process											owl:Class	
GO:0060684	biolink:NamedThing	epithelial-mesenchymal cell signaling	Any process that results in the transfer of information from an epithelial cell to a mesenchymal cell where it is interpreted.	tmpzr1t_l9r_go_relaxed.owl	epithelial-mesenchymal cell signalling							dph	2009-06-03T06:36:46Z					biological_process											owl:Class	
GO:1902299	biolink:NamedThing	pre-replicative complex assembly involved in cell cycle DNA replication	Any pre-replicative complex assembly that is involved in cell cycle DNA replication.	tmpzr1t_l9r_go_relaxed.owl	pre-RC assembly involved in cell cycle DNA replication|pre-replication complex assembly involved in cell cycle DNA replication							jl	2013-07-10T11:47:28Z					biological_process											owl:Class	
GO:0036388	biolink:NamedThing	pre-replicative complex assembly	The aggregation, arrangement and bonding together of a set of components to form the pre-replicative complex, a protein-DNA complex that forms at the origin of replication during the initial step of DNA replication and allows the origin to become competent, or 'licensed', for replication.	tmpzr1t_l9r_go_relaxed.owl	pre-replication complex assembly|pre-RC assembly							bf	2013-06-05T16:29:13Z					biological_process											owl:Class	
GO:1904839	biolink:NamedThing	negative regulation of male germ-line stem cell asymmetric division	Any process that stops, prevents or reduces the frequency, rate or extent of male germ-line stem cell asymmetric division.	tmpzr1t_l9r_go_relaxed.owl	inhibition of male germ-line stem cell asymmetric division|down-regulation of male germ-line stem cell asymmetric division|down regulation of male germ-line stem cell renewal|down-regulation of male germ-line stem cell renewal|inhibition of male germ-line stem cell renewal|down regulation of male germ-line stem cell asymmetric division|downregulation of male germ-line stem cell asymmetric division|downregulation of male germ-line stem cell renewal|negative regulation of male germ-line stem cell renewal							sl	2015-12-05T00:28:39Z					biological_process											owl:Class	
GO:0045769	biolink:NamedThing	negative regulation of asymmetric cell division	Any process that stops, prevents, or reduces the frequency, rate or extent of asymmetric cell division.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of asymmetric cell division|inhibition of asymmetric cell division|down regulation of asymmetric cell division|downregulation of asymmetric cell division													biological_process											owl:Class	
GO:0032045	biolink:NamedThing	guanyl-nucleotide exchange factor complex	A protein complex that stimulates the exchange of guanyl nucleotides associated with a GTPase.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0090351	biolink:NamedThing	seedling development	The process whose specific outcome is the progression of the seedling over time, beginning with seed germination and ending when the first adult leaves emerge.	tmpzr1t_l9r_go_relaxed.owl					PO:0008037			tb	2010-06-10T03:33:10Z					biological_process											owl:Class	
GO:0044659	biolink:NamedThing	viral release from host cell by cytolysis	The killing by a virus of a cell by means of the rupture of cell membranes and the loss of cytoplasm.	tmpzr1t_l9r_go_relaxed.owl	lytic viral release|lytic viral life cycle|viral release by cell lysis|viral exit from host cell by cytolysis|viral release by host cell lysis|cytolysis by virus of host cell	https://github.com/geneontology/go-ontology/issues/18852			VZ:1077			jl	2012-08-01T13:16:39Z			GO:0046756|GO:0019077		biological_process											owl:Class	
GO:0019076	biolink:NamedThing	viral release from host cell	The dissemination of mature viral particles from the host cell, e.g. by cell lysis or the budding of virus particles from the cell membrane.	tmpzr1t_l9r_go_relaxed.owl	viral shedding|virus exit from host cell|viral exit|viral release|release of virus from host				VZ:1076									biological_process											owl:Class	
GO:0004790	biolink:NamedThing	thioether S-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine(1+) + dimethyl sulfide = S-adenosyl-L-homocysteine + trimethylsulfonium.	tmpzr1t_l9r_go_relaxed.owl	S-adenosyl-L-methionine:dimethyl-sulfide S-methyltransferase activity|thioether methyltransferase activity|S-adenosyl-L-methionine:thioether S-methyltransferase activity				RHEA:19613|KEGG_REACTION:R02572|MetaCyc:THIOETHER-S-METHYLTRANSFERASE-RXN|EC:2.1.1.96									molecular_function											owl:Class	
GO:0008172	biolink:NamedThing	S-methyltransferase activity	Catalysis of the transfer of a methyl group to the sulfur atom of an acceptor molecule.	tmpzr1t_l9r_go_relaxed.owl					EC:2.1.1.-|Reactome:R-HSA-209821									molecular_function											owl:Class	
GO:0031214	biolink:NamedThing	biomineral tissue development	Formation of hard tissues that consist mainly of inorganic compounds, and also contain a small amounts of organic matrices that are believed to play important roles in their formation.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Biomineralization									biological_process											owl:Class	
GO:0110148	biolink:NamedThing	biomineralization	The process where mineral crystals are formed and deposited in an organized fashion in a matrix (either cellular or extracellular) by living organisms. This gives rise to inorganic compound-based structures such as skeleton, teeth, ivory, shells, cuticle, and corals as well as bacterial biomineralization products.	tmpzr1t_l9r_go_relaxed.owl	mineralization|biomineral formation|biomineralisation|mineralisation				Wikipedia:Biomineralization			kmv	2019-06-10T17:55:28Z					biological_process											owl:Class	
GO:0102784	biolink:NamedThing	lutein oxygenase activity	Catalysis of the reaction: lutein + 2 O2 = 3-hydroxy-beta-ionone + 3-hydroxy-alpha-ionone + 4,9-dimethyldodeca-2,4,6,8,10-pentaenedial.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-7884									molecular_function											owl:Class	
GO:0033842	biolink:NamedThing	N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity	Catalysis of the reaction: UDP-N-acetyl-D-galactosamine + N-acetyl-beta-D-glucosaminyl group = UDP + N-acetyl-beta-D-galactosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl group.	tmpzr1t_l9r_go_relaxed.owl	beta4GalNAc-T3|beta1,4-N-acetylgalactosaminyltransferase activity|UDP-N-acetyl-D-galactosamine:N-acetyl-D-glucosaminyl-group beta-1,4-N-acetylgalactosaminyltransferase activity|beta1,4-N-acetylgalactosaminyltransferase IV activity|beta4GalNAc-T4|beta1,4-N-acetylgalactosaminyltransferase III activity				RHEA:20493|MetaCyc:2.4.1.244-RXN|EC:2.4.1.244									molecular_function											owl:Class	
GO:0008376	biolink:NamedThing	acetylgalactosaminyltransferase activity	Catalysis of the transfer of an N-acetylgalactosaminyl residue from UDP-N-acetyl-galactosamine to an oligosaccharide.	tmpzr1t_l9r_go_relaxed.owl	GalNAc transferase activity				Reactome:R-HSA-9605700|Reactome:R-HSA-8931648|Reactome:R-HSA-8855954									molecular_function											owl:Class	
GO:0035434	biolink:NamedThing	copper ion transmembrane transport	The directed movement of copper cation across a membrane.	tmpzr1t_l9r_go_relaxed.owl	copper cation transmembrane transport|copper ion membrane transport					Note that this term is not intended for use in annotating lateral movement within membranes.		bf	2010-04-08T11:03:23Z			GO:1901473		biological_process											owl:Class	
GO:0052634	biolink:NamedThing	C-19 gibberellin 2-beta-dioxygenase activity	Catalysis of the reaction: a C-19 gibberellin + 2-oxoglutarate + O2 = a C-19 2-beta-hydroxygibberellin + succinate + CO2. C-19 gibberellin refers to a gibberellin with nineteen carbons.	tmpzr1t_l9r_go_relaxed.owl	C-19 gibberellin 2beta-hydroxylase activity|C-19 gibberellin 2-oxidase activity|(C-19 gibberellin-1),2-oxoglutarate:oxygen oxidoreductase (2beta-hydroxylating)|C-19 gibberellin 2beta-dioxygenase activity|C-19 gibberellin 2-beta-hydroxylase activity|C(19) gibberellin 2-oxidase activity|C-19 GA 2-oxidase activity				EC:1.14.11.13									molecular_function											owl:Class	
GO:0045345	biolink:NamedThing	positive regulation of MHC class I biosynthetic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of MHC class I.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of MHC class I synthesis|positive regulation of MHC class I biosynthesis|positive regulation of MHC class I anabolism|positive regulation of major histocompatibility complex class I biosynthetic process|up-regulation of MHC class I biosynthetic process|activation of MHC class I biosynthetic process|stimulation of MHC class I biosynthetic process|up regulation of MHC class I biosynthetic process|positive regulation of MHC class I formation|upregulation of MHC class I biosynthetic process|positive regulation of major histocompatibility complex class I biosynthesis													biological_process											owl:Class	
GO:0010847	biolink:NamedThing	regulation of chromatin assembly	Any process the modulates the frequency, rate or extent of chromatin assembly. Chromatin assembly is the assembly of DNA, histone proteins, and other associated proteins into chromatin structure, beginning with the formation of the basic unit, the nucleosome, followed by organization of the nucleosomes into higher order structures, ultimately giving rise to a complex organization of specific domains within the nucleus.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0007056	biolink:NamedThing	spindle assembly involved in female meiosis	The aggregation, arrangement and bonding together of a set of components to form the spindle during a meiotic cell cycle in females. An example of this is found in Drosophila melanogaster.	tmpzr1t_l9r_go_relaxed.owl	female meiotic spindle assembly													biological_process											owl:Class	
GO:0071630	biolink:NamedThing	nuclear protein quality control by the ubiquitin-proteasome system	The chemical reactions and pathways resulting in the breakdown of misfolded proteins via a mechanism in which the proteins are transported to the nucleus for ubiquitination, and then targeted to proteasomes for degradation.	tmpzr1t_l9r_go_relaxed.owl	nucleus-associated proteasomal ubiquitin-dependent protein degradation|ubiquitin-dependent catabolism of misfolded proteins by nucleus-associated proteasome|nucleus-associated proteasomal ubiquitin-dependent protein breakdown|nucleus-associated proteasomal ubiquitin-dependent protein catabolism					See also the biological process terms 'unfolded protein response ; GO:0030968' and 'retrograde protein transport, ER to cytosol ; GO:0030970'.		mah	2010-02-11T03:31:46Z					biological_process											owl:Class	
GO:0006515	biolink:NamedThing	protein quality control for misfolded or incompletely synthesized proteins	The chemical reactions and pathways resulting in the breakdown of misfolded or attenuated proteins.	tmpzr1t_l9r_go_relaxed.owl	protein quality control by the ubiquitin-proteasome system|misfolded or incompletely synthesized protein catabolism|misfolded or incompletely synthesized protein breakdown|degradation of misfolded or incompletely synthesized proteins|misfolded or incompletely synthesized protein degradation|misfolded or incompletely synthesized protein catabolic process|protein quality control (PQC)													biological_process											owl:Class	
GO:0032351	biolink:NamedThing	negative regulation of hormone metabolic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving any hormone.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of hormone metabolism|downregulation of hormone metabolic process|down-regulation of hormone metabolic process|inhibition of hormone metabolic process|down regulation of hormone metabolic process													biological_process											owl:Class	
GO:1902206	biolink:NamedThing	negative regulation of interleukin-2-mediated signaling pathway	Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-2-mediated signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	inhibition of interleukin-2-mediated signalling pathway|inhibition of IL-2-mediated signaling pathway|downregulation of interleukin-2-mediated signalling pathway|inhibition of interleukin-2-mediated signaling pathway|down-regulation of interleukin-2-mediated signaling pathway|down-regulation of interleukin-2-mediated signalling pathway|down regulation of interleukin-2-mediated signaling pathway|downregulation of interleukin-2-mediated signaling pathway|down regulation of IL-2-mediated signaling pathway|negative regulation of interleukin-2-mediated signalling pathway|downregulation of IL-2-mediated signaling pathway|down-regulation of IL-2-mediated signaling pathway|negative regulation of IL-2-mediated signaling pathway|down regulation of interleukin-2-mediated signalling pathway							lb	2013-06-11T07:34:45Z					biological_process											owl:Class	
GO:1902205	biolink:NamedThing	regulation of interleukin-2-mediated signaling pathway	Any process that modulates the frequency, rate or extent of interleukin-2-mediated signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	regulation of interleukin-2-mediated signalling pathway|regulation of IL-2-mediated signaling pathway							lb	2013-06-11T07:34:39Z					biological_process											owl:Class	
GO:0036274	biolink:NamedThing	response to lapatinib	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lapatinib stimulus.	tmpzr1t_l9r_go_relaxed.owl						Note that this term is in the subset of terms that should not be used for direct manual annotation of gene products. It was created to be used for cross-referencing by other ontologies. Direct annotations to this term may be amended during annotation QC.		bf	2012-07-09T02:02:26Z					biological_process											owl:Class	
GO:0044833	biolink:NamedThing	modulation by virus of host protein transport	Any viral process that modulates the frequency, rate or extent of protein transport in its host organism.	tmpzr1t_l9r_go_relaxed.owl								jl	2014-02-06T13:25:52Z					biological_process											owl:Class	
GO:0052038	biolink:NamedThing	modulation by symbiont of host intracellular transport	Any process in which an organism modulates the frequency, rate or extent of the directed movement of substances within the cell or cells of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	modulation of host intracellular trafficking													biological_process											owl:Class	
GO:0090215	biolink:NamedThing	regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity	Any process that modulates the frequency, rate or extent of the catalysis of the reaction: ATP + 1-phosphatidyl-1D-myo-inositol 4-phosphate = ADP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate.	tmpzr1t_l9r_go_relaxed.owl								tb	2010-01-12T10:00:45Z					biological_process											owl:Class	
GO:0043550	biolink:NamedThing	regulation of lipid kinase activity	Any process that modulates the frequency, rate or extent of lipid kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a simple or complex lipid.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0140013	biolink:NamedThing	meiotic nuclear division	One of the two nuclear divisions that occur as part of the meiotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl	meiosis	https://github.com/geneontology/go-ontology/issues/19910						pg	2017-03-23T09:40:00Z					biological_process											owl:Class	
GO:0000280	biolink:NamedThing	nuclear division	The division of a cell nucleus into two nuclei, with DNA and other nuclear contents distributed between the daughter nuclei.	tmpzr1t_l9r_go_relaxed.owl	karyokinesis													biological_process											owl:Class	
GO:0051682	biolink:NamedThing	galactomannan catabolic process	The chemical reactions and pathways resulting in the breakdown of galactomannan, a polysaccharide composed of D-galactosyl and D-mannosyl. The mannosyl units form the backbone structure (a linear main chain) with the D-galactosyl as single side units.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0051069	biolink:NamedThing	galactomannan metabolic process	The chemical reactions and pathways involving galactomannan, a polysaccharide composed of D-galactose and D-mannose. The mannose units form the backbone structure (a linear main chain) with the D-galactose as single side units.	tmpzr1t_l9r_go_relaxed.owl	galactomannan metabolism													biological_process											owl:Class	
GO:1903254	biolink:NamedThing	hercynylselenocysteine metabolic process	The chemical reactions and pathways involving hercynylselenocysteine.	tmpzr1t_l9r_go_relaxed.owl	hercynylselenocysteine metabolism							mah	2014-08-06T09:14:08Z					biological_process											owl:Class	
GO:0052701	biolink:NamedThing	cellular modified histidine metabolic process	The chemical reactions and pathways involving compounds derived from histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid.	tmpzr1t_l9r_go_relaxed.owl	modified histidine metabolic process|cellular histidine derivative metabolism|cellular histidine derivative metabolic process|modified histidine metabolism|cellular modified histidine metabolism|histidine derivative metabolic process								2011-08-01T03:47:00Z					biological_process											owl:Class	
GO:0032333	biolink:NamedThing	activin secretion	The regulated release of activin, a nonsteroidal regulator composed of two covalently linked beta subunits, which is synthesized in the pituitary gland and gonads and stimulates the secretion of follicle-stimulating hormone.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0046879	biolink:NamedThing	hormone secretion	The regulated release of hormones, substances with a specific regulatory effect on a particular organ or group of cells.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:2000984	biolink:NamedThing	negative regulation of ATP citrate synthase activity	Any process that stops, prevents or reduces the frequency, rate or extent of ATP citrate synthase activity.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of citric cleavage enzyme activity|negative regulation of acetyl-CoA:oxaloacetate C-acetyltransferase [(pro-S)-carboxymethyl-forming, ADP-phosphorylating]|negative regulation of citrate-ATP lyase activity|negative regulation of ATP-citrate (pro-S-)-lyase activity|negative regulation of ATP:citrate oxaloacetate-lyase [(pro-S)-CH2COO-rightacetyl-CoA] (ATP-dephosphorylating)|negative regulation of ATP-citrate (pro-S)-lyase activity|negative regulation of acetyl-CoA:oxaloacetate acetyltransferase (isomerizing; ADP- phosphorylating) activity|negative regulation of citrate cleavage enzyme activity|negative regulation of acetyl-CoA:oxaloacetate acetyltransferase (isomerizing; ADP-phosphorylating)|negative regulation of ATP citrate (pro-S)-lyase activity|negative regulation of adenosine triphosphate citrate lyase activity|negative regulation of ATP-citric lyase activity|negative regulation of ATP:citrate oxaloacetate-lyase ((pro-S)-CH(2)COO(-)->acetyl-CoA) (ATP- dephosphorylating) activity							vk	2011-08-04T03:15:28Z					biological_process											owl:Class	
GO:2000983	biolink:NamedThing	regulation of ATP citrate synthase activity	Any process that modulates the frequency, rate or extent of ATP citrate synthase activity.	tmpzr1t_l9r_go_relaxed.owl	regulation of ATP-citrate (pro-S-)-lyase activity|regulation of ATP:citrate oxaloacetate-lyase [(pro-S)-CH2COO-rightacetyl-CoA] (ATP-dephosphorylating)|regulation of ATP-citrate (pro-S)-lyase activity|regulation of ATP citrate (pro-S)-lyase activity|regulation of citric cleavage enzyme activity|regulation of ATP-citric lyase activity|regulation of ATP:citrate oxaloacetate-lyase ((pro-S)-CH(2)COO(-)->acetyl-CoA) (ATP- dephosphorylating) activity|regulation of citrate-ATP lyase activity|regulation of acetyl-CoA:oxaloacetate C-acetyltransferase [(pro-S)-carboxymethyl-forming, ADP-phosphorylating]|regulation of acetyl-CoA:oxaloacetate acetyltransferase (isomerizing; ADP-phosphorylating)|regulation of adenosine triphosphate citrate lyase activity|regulation of acetyl-CoA:oxaloacetate acetyltransferase (isomerizing; ADP- phosphorylating) activity|regulation of citrate cleavage enzyme activity							vk	2011-08-04T03:15:24Z					biological_process											owl:Class	
GO:0007266	biolink:NamedThing	Rho protein signal transduction	A series of molecular signals within the cell that are mediated by a member of the Rho family of proteins switching to a GTP-bound active state.	tmpzr1t_l9r_go_relaxed.owl	Rho mediated signal transduction													biological_process											owl:Class	
GO:0007265	biolink:NamedThing	Ras protein signal transduction	A series of molecular signals within the cell that are mediated by a member of the Ras superfamily of proteins switching to a GTP-bound active state.	tmpzr1t_l9r_go_relaxed.owl	Ras mediated signal transduction													biological_process											owl:Class	
GO:0036430	biolink:NamedThing	CMP kinase activity	Catalysis of the reaction: ATP + CMP = ADP + CDP.	tmpzr1t_l9r_go_relaxed.owl					RHEA:11600|KEGG_REACTION:R00512|MetaCyc:RXN-11832			bf	2013-09-16T14:11:48Z					molecular_function											owl:Class	
GO:0004127	biolink:NamedThing	cytidylate kinase activity	Catalysis of the reaction: ATP + (d)CMP = ADP + (d)CDP.	tmpzr1t_l9r_go_relaxed.owl	deoxycytidine monophosphokinase activity|dCMP kinase activity|pyrimidine nucleoside monophosphate kinase activity|cytidine monophosphate kinase activity|ATP:UMP-CMP phosphotransferase activity|UMP-CMP kinase activity|deoxycytidylate kinase activity|CMP kinase activity|ATP:CMP phosphotransferase activity|CTP:CMP phosphotransferase activity				EC:2.7.4.14|MetaCyc:CMPKI-RXN									molecular_function											owl:Class	
GO:0071388	biolink:NamedThing	cellular response to cortisone stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cortisone stimulus. Cortisone is a natural glucocorticoid steroid hormone that is metabolically convertible to cortisol. Cortisone is synthesized from cholesterol in the cortex of the adrenal gland under the stimulation of adrenocorticotropin hormone (ACTH). The main physiological effect of cortisone is on carbohydrate metabolism; it can stimulate increased glucose release from the liver, increased liver glycogen synthesis, and decreased utilization of glucose by the tissues.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-12-11T03:57:59Z					biological_process											owl:Class	
GO:0071385	biolink:NamedThing	cellular response to glucocorticoid stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucocorticoid stimulus. Glucocorticoids are hormonal C21 corticosteroids synthesized from cholesterol with the ability to bind with the cortisol receptor and trigger similar effects. Glucocorticoids act primarily on carbohydrate and protein metabolism, and have anti-inflammatory effects.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-12-11T03:53:56Z					biological_process											owl:Class	
GO:0018496	biolink:NamedThing	2,6-dihydroxycyclohexane-1-carboxyl-CoA dehydrogenase activity	Catalysis of the reaction: 2,6-dihydroxycyclohexane-1-carboxyl-CoA = 2 H+ + 2 e- + 6-oxo-2-hydroxycyclohexane-1-carboxyl-CoA.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0205									molecular_function											owl:Class	
GO:0018755	biolink:NamedThing	2-chloro-4-hydroxy-6-amino-1,3,5-triazine aminohydrolase activity	Catalysis of the reaction: 2-chloro-4-hydroxy-6-amino-1,3,5-triazine + OH- = 2,4-dihydroxy-6-amino-1,3,5-triazine + Cl-.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1902417	biolink:NamedThing	(+)-abscisic acid D-glucopyranosyl ester transmembrane transporter activity	Enables the transfer of (+)-abscisic acid D-glucopyranosyl ester from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	ABA-GE transmembrane transporter activity|abscisic acid glucosyl ester transmembrane transporter activity							tb	2013-09-16T22:37:11Z					molecular_function											owl:Class	
GO:0042947	biolink:NamedThing	glucoside transmembrane transporter activity	Enables the transfer of glucosides from one side of a membrane to the other. Glucosides are glycosides in which the sugar group is a glucose residue.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0045994	biolink:NamedThing	positive regulation of translational initiation by iron	Any process involving iron that activates or increases the rate of translational initiation.	tmpzr1t_l9r_go_relaxed.owl	up regulation of translational initiation by iron|stimulation of translational initiation by iron|upregulation of translational initiation by iron|activation of translational initiation by iron|up-regulation of translational initiation by iron													biological_process											owl:Class	
GO:0032876	biolink:NamedThing	negative regulation of DNA endoreduplication	Any process that stops, prevents, or reduces the frequency, rate or extent of DNA endoreduplication.	tmpzr1t_l9r_go_relaxed.owl	inhibition of DNA endoreduplication|downregulation of DNA endoreduplication|down-regulation of DNA endoreduplication|negative regulation of DNA endoreplication|negative regulation of DNA re-duplication|down regulation of DNA endoreduplication													biological_process											owl:Class	
GO:0032875	biolink:NamedThing	regulation of DNA endoreduplication	Any process that modulates the frequency, rate or extent of DNA endoreduplication.	tmpzr1t_l9r_go_relaxed.owl	regulation of DNA endoreplication|regulation of DNA re-duplication													biological_process											owl:Class	
GO:0061106	biolink:NamedThing	negative regulation of stomach neuroendocrine cell differentiation	Any process that decreases the rate, frequency or extent of the differentiation of a neuroendocrine cell in the stomach.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-04-29T12:23:05Z					biological_process											owl:Class	
GO:0036112	biolink:NamedThing	medium-chain fatty-acyl-CoA metabolic process	The chemical reactions and pathways involving medium-chain fatty-acyl-CoAs, any derivative of coenzyme A in which the sulfhydryl group is in a thioester linkage with a long-chain fatty-acyl group. A medium-chain fatty acid is a fatty acid with a chain length of between C6 and C12.	tmpzr1t_l9r_go_relaxed.owl	medium-chain fatty acyl-CoA metabolism|medium-chain fatty acyl CoA metabolic process							bf	2012-02-15T11:12:19Z					biological_process											owl:Class	
GO:0035337	biolink:NamedThing	fatty-acyl-CoA metabolic process	The chemical reactions and pathways involving a fatty-acyl-CoA, any derivative of coenzyme A in which the sulfhydryl group is in thiolester linkage with a fatty-acyl group.	tmpzr1t_l9r_go_relaxed.owl	fatty acyl CoA metabolic process|fatty-acyl-CoA metabolism							bf	2010-03-02T11:05:48Z					biological_process											owl:Class	
GO:0005663	biolink:NamedThing	DNA replication factor C complex	A complex that loads the DNA polymerase processivity factor proliferating cell nuclear antigen (PCNA) onto DNA, thereby permitting processive DNA synthesis catalyzed by DNA polymerase. In eukaryotes the complex consists of five polypeptides.	tmpzr1t_l9r_go_relaxed.owl	activator 1 complex|RFC complex													cellular_component											owl:Class	
GO:1903457	biolink:NamedThing	lactate catabolic process	The chemical reactions and pathways resulting in the breakdown of lactate.	tmpzr1t_l9r_go_relaxed.owl	lactate degradation|lactate breakdown|lactate catabolism							pr	2014-09-23T08:41:03Z					biological_process											owl:Class	
GO:0002798	biolink:NamedThing	negative regulation of antibacterial peptide secretion	Any process that stops, prevents, or reduces the frequency, rate, or extent of antibacterial peptide secretion.	tmpzr1t_l9r_go_relaxed.owl	downregulation of antibacterial peptide secretion|down-regulation of antibacterial peptide secretion|down regulation of antibacterial peptide secretion|inhibition of antibacterial peptide secretion													biological_process											owl:Class	
GO:0002797	biolink:NamedThing	regulation of antibacterial peptide secretion	Any process that modulates the frequency, rate, or extent of antibacterial peptide secretion.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1902614	biolink:NamedThing	positive regulation of anti-Mullerian hormone signaling pathway	Any process that activates or increases the frequency, rate or extent of anti-Mullerian hormone signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of anti-Mullerian hormone signaling pathway|up regulation of anti-Mullerian hormone signaling pathway|activation of anti-Mullerian hormone signaling pathway|upregulation of anti-Mullerian hormone signaling pathway							hjd	2014-01-09T15:39:48Z					biological_process											owl:Class	
GO:1902612	biolink:NamedThing	regulation of anti-Mullerian hormone signaling pathway	Any process that modulates the frequency, rate or extent of anti-Mullerian hormone signaling pathway.	tmpzr1t_l9r_go_relaxed.owl								hjd	2014-01-09T15:39:30Z					biological_process											owl:Class	
GO:0072200	biolink:NamedThing	negative regulation of mesenchymal cell proliferation involved in ureter development	Any process that decreases the frequency, rate or extent of mesenchymal cell proliferation that contributes to the progression of the ureter gland over time. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of ureteral mesenchymal cell proliferation|negative regulation of ureter mesenchymal cell proliferation							mah	2010-03-01T03:42:31Z					biological_process											owl:Class	
GO:1901613	biolink:NamedThing	negative regulation of terminal button organization	Any process that stops, prevents or reduces the frequency, rate or extent of terminal button organization.	tmpzr1t_l9r_go_relaxed.owl	down regulation of bouton organization|negative regulation of bouton organization|negative regulation of presynaptic bouton organization|down-regulation of presynaptic bouton organization|down regulation of presynaptic bouton organization|negative regulation of terminal button organisation|negative regulation of synaptic bouton organization|inhibition of presynaptic bouton organization|down-regulation of terminal bouton organization|downregulation of presynaptic bouton organization|inhibition of synaptic bouton organization|down-regulation of synaptic bouton organization|inhibition of terminal bouton organization|down regulation of synaptic bouton organization|inhibition of bouton organization|downregulation of synaptic bouton organization|downregulation of terminal button organization|inhibition of terminal button organization|downregulation of bouton organization|down regulation of terminal bouton organization|down-regulation of terminal button organisation|negative regulation of terminal bouton organization|downregulation of terminal button organisation|down regulation of terminal button organization|downregulation of terminal bouton organization|down-regulation of bouton organization|down-regulation of terminal button organization|down regulation of terminal button organisation|inhibition of terminal button organisation							lb	2012-11-13T10:40:51Z					biological_process											owl:Class	
GO:2000054	biolink:NamedThing	negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification	Any process that stops, prevents, or reduces the frequency, rate or extent of Wnt signaling pathway involved in dorsal/ventral axis specification.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of Wnt receptor signalling pathway involved in dorsal/ventral axis specification|negative regulation of Wnt-activated signaling pathway involved in dorsal/ventral axis specification|negative regulation of Wnt receptor signaling pathway involved in dorsal/ventral axis specification							jl	2010-08-20T01:13:35Z					biological_process											owl:Class	
GO:1904516	biolink:NamedThing	myofibroblast cell apoptotic process	Any apoptotic process in a myofibroblast cell.	tmpzr1t_l9r_go_relaxed.owl	MFB apoptosis|myofibroblast cell apoptosis|MFB apoptotic process							sl	2015-07-28T18:29:08Z					biological_process											owl:Class	
GO:0052103	biolink:NamedThing	induction by symbiont of host induced systemic resistance	Any process in which a symbiont activates, maintains or increases the frequency, rate or extent of induced systemic resistance in the host organism; induced systemic resistance is a response that confers broad spectrum systemic resistance to disease and that does not depend upon salicylic acid signaling. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	positive regulation by symbiont of host induced systemic resistance|upregulation by symbiont of induced systemic resistance in host|up regulation by symbiont of induced systemic resistance in host|activation by organism of ISR in host|induction by symbiont of induced systemic resistance in host|induction by organism of ISR in host|up-regulation by symbiont of induced systemic resistance in host|activation by organism of induced systemic resistance in host|stimulation by symbiont of induced systemic resistance in host|activation by symbiont of induced systemic resistance in host|positive regulation by symbiont of induced systemic resistance in host|positive regulation by organism of induced systemic resistance in other organism involved in symbiotic interaction|induction by organism of induced systemic resistance in other organism involved in symbiotic interaction											GO:0052532|GO:0052288|GO:0052533		biological_process											owl:Class	
GO:0052159	biolink:NamedThing	modulation by symbiont of host induced systemic resistance	Any process in which a symbiont modulates the frequency, rate or extent of induced systemic resistance in the host organism; induced systemic resistance is a response that confers broad spectrum systemic resistance to disease and that does not depend upon salicylic acid signaling. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	modulation by organism of induced systemic resistance in other organism involved in symbiotic interaction|modulation by symbiont of induced systemic resistance in host											GO:0052298		biological_process											owl:Class	
GO:1902683	biolink:NamedThing	regulation of receptor localization to synapse	Any process that modulates the frequency, rate or extent of receptor localization to synapse.	tmpzr1t_l9r_go_relaxed.owl	regulation of receptor localisation to synapse							kmv	2014-02-07T17:38:31Z					biological_process											owl:Class	
GO:0034219	biolink:NamedThing	carbohydrate transmembrane transport	The process in which a carbohydrate is transported across a membrane.	tmpzr1t_l9r_go_relaxed.owl	transmembrane carbohydrate transport|carbohydrate membrane transport					Note that this term is not intended for use in annotating lateral movement within membranes.								biological_process											owl:Class	
GO:1905366	biolink:NamedThing	negative regulation of intralumenal vesicle formation	Any process that stops, prevents or reduces the frequency, rate or extent of intralumenal vesicle formation.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of endosome membrane budding|downregulation of endosome membrane budding|downregulation of intralumenal vesicle formation|negative regulation of endosome membrane budding|inhibition of intralumenal vesicle formation|down-regulation of intralumenal vesicle formation|inhibition of endosome membrane budding|down regulation of endosome membrane budding|down regulation of intralumenal vesicle formation							bc	2016-08-16T12:00:09Z					biological_process											owl:Class	
GO:1904979	biolink:NamedThing	negative regulation of endosome organization	Any process that stops, prevents or reduces the frequency, rate or extent of endosome organization.	tmpzr1t_l9r_go_relaxed.owl	inhibition of endosome organisation|down regulation of endosome organization and biogenesis|downregulation of endosome organization and biogenesis|downregulation of endosome organization|down regulation of endosome organisation|inhibition of endosome organization and biogenesis|down-regulation of endosome organisation|negative regulation of endosome organisation|down-regulation of endosome organization and biogenesis|negative regulation of endosome organization and biogenesis|down-regulation of endosome organization|inhibition of endosome organization|down regulation of endosome organization|downregulation of endosome organisation							pad	2016-02-22T19:21:08Z					biological_process											owl:Class	
GO:0051078	biolink:NamedThing	meiotic nuclear membrane disassembly	The cell cycle process in which the controlled breakdown of the nuclear membranes during meiotic cell division occurs.	tmpzr1t_l9r_go_relaxed.owl	meiotic nuclear envelope catabolism|meiotic nuclear envelope disassembly|meiotic nuclear envelope degradation|meiotic nuclear envelope breakdown													biological_process											owl:Class	
GO:1903046	biolink:NamedThing	meiotic cell cycle process	A process that is part of the meiotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl								jl	2014-05-22T14:22:28Z					biological_process											owl:Class	
GO:0010938	biolink:NamedThing	cytoplasmic microtubule depolymerization	The removal of tubulin heterodimers from one or both ends of a cytoplasmic microtubule.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0007019	biolink:NamedThing	microtubule depolymerization	The removal of tubulin heterodimers from one or both ends of a microtubule.	tmpzr1t_l9r_go_relaxed.owl	microtubule shortening|microtubule catastrophe|microtubule disassembly|microtubule depolymerization during nuclear congression													biological_process											owl:Class	
GO:0016031	biolink:NamedThing	tRNA import into mitochondrion	The process in which a tRNA is transported from the cytosol into the mitochondrial matrix.	tmpzr1t_l9r_go_relaxed.owl	cytoplasmic tRNA, mitochondrial import|cytoplasmic tRNA transport into mitochondrion|nuclear-encoded tRNA import into mitochondrion|cytoplasmic tRNA import into mitochondrion|mitochondrial import of cytoplasmic tRNA|cytoplasmic tRNA import into mitochondria													biological_process											owl:Class	
GO:0035927	biolink:NamedThing	RNA import into mitochondrion	The process in which a rRNA, ribosomal ribonucleic acid, is transported from the cytosol into the mitochondrial matrix.	tmpzr1t_l9r_go_relaxed.owl	cytoplasmic RNA import into mitochondrion|nuclear-encoded RNA import into mitochondrion							bf	2011-07-19T09:39:37Z					biological_process											owl:Class	
GO:0016864	biolink:NamedThing	intramolecular oxidoreductase activity, transposing S-S bonds	Catalysis of an oxidation-reduction (redox) reaction in which the hydrogen donor and acceptor are the same molecule, one or more sulfur-sulfur bonds in the molecule are rearranged, and no oxidized product appears.	tmpzr1t_l9r_go_relaxed.owl	intramolecular isomerase activity, transposing S-S bonds				EC:5.3.4.-									molecular_function											owl:Class	
GO:0016860	biolink:NamedThing	intramolecular oxidoreductase activity	Catalysis of an oxidation-reduction (redox) reaction in which the hydrogen donor and acceptor are the same molecule, and no oxidized product appears.	tmpzr1t_l9r_go_relaxed.owl	intramolecular isomerase activity|intramolecular oxidoreductase activity, other intramolecular oxidoreductases				EC:5.3.-.-|Reactome:R-HSA-109998									molecular_function											owl:Class	
GO:0048700	biolink:NamedThing	acquisition of desiccation tolerance in seed	The process in which a seed acquires tolerance to severe drying, before entering into a dry, either dormant or quiescent state.	tmpzr1t_l9r_go_relaxed.owl	acquisition of desiccation tolerance													biological_process											owl:Class	
GO:0097439	biolink:NamedThing	acquisition of desiccation tolerance	The process in which tolerance to severe drying is acquired, before entering into a dry, either dormant or quiescent state.	tmpzr1t_l9r_go_relaxed.owl								pr	2012-12-05T15:09:52Z					biological_process											owl:Class	
GO:0140487	biolink:NamedThing	metal ion sequestering activity	The selective interaction of a protein with a metal ion to prevent it from interacting with sensitive components of a biological system.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/19700						pg	2020-06-29T09:23:47Z					molecular_function											owl:Class	
GO:0140313	biolink:NamedThing	molecular sequestering activity	The selective interaction of a protein with a specific molecule to prevent it from interacting with other partners or inhibiting its localization to other areas of the cell.	tmpzr1t_l9r_go_relaxed.owl								pg	2019-03-28T10:00:25Z					molecular_function											owl:Class	
GO:1901383	biolink:NamedThing	negative regulation of chorionic trophoblast cell proliferation	Any process that stops, prevents or reduces the frequency, rate or extent of chorionic trophoblast cell proliferation.	tmpzr1t_l9r_go_relaxed.owl	inhibition of chorionic trophoblast cell proliferation|downregulation of chorionic trophoblast cell proliferation|down-regulation of chorionic trophoblast cell proliferation|down regulation of chorionic trophoblast cell proliferation							vk	2012-10-01T10:04:23Z					biological_process											owl:Class	
GO:0035438	biolink:NamedThing	cyclic-di-GMP binding	Binding to cyclic-di-GMP, cyclic dimeric guanosine monophosphate.	tmpzr1t_l9r_go_relaxed.owl	cyclic dinucleotide di-GMP binding|c-di-GMP binding|3',5'-cyclic di-GMP binding							bf	2010-04-09T02:40:17Z					molecular_function											owl:Class	
GO:0099587	biolink:NamedThing	inorganic ion import across plasma membrane	The directed movement of inorganic ions from outside of a cell, across the plasma membrane and into the cytosol.	tmpzr1t_l9r_go_relaxed.owl	inorganic ion import into cell													biological_process											owl:Class	
GO:0031754	biolink:NamedThing	Edg-1 sphingosine 1-phosphate receptor binding	Binding to an Edg-1 sphingosine 1-phosphate receptor.	tmpzr1t_l9r_go_relaxed.owl	Edg-1 sphingosine 1-phosphate receptor ligand													molecular_function											owl:Class	
GO:0031753	biolink:NamedThing	endothelial differentiation G protein-coupled receptor binding	Binding to an endothelial differentiation G protein-coupled receptor.	tmpzr1t_l9r_go_relaxed.owl	endothelial differentiation G-protein coupled receptor ligand|endothelial differentiation G-protein coupled receptor binding													molecular_function											owl:Class	
GO:0042669	biolink:NamedThing	regulation of inner ear auditory receptor cell fate specification	Any process that mediates the specification of a cell into an auditory hair cell.	tmpzr1t_l9r_go_relaxed.owl	regulation of auditory hair cell fate specification													biological_process											owl:Class	
GO:0042659	biolink:NamedThing	regulation of cell fate specification	Any process that mediates the adoption of a specific fate by a cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1901019	biolink:NamedThing	regulation of calcium ion transmembrane transporter activity	Any process that modulates the frequency, rate or extent of calcium ion transmembrane transporter activity.	tmpzr1t_l9r_go_relaxed.owl								rl	2012-06-15T07:54:12Z					biological_process											owl:Class	
GO:1903169	biolink:NamedThing	regulation of calcium ion transmembrane transport	Any process that modulates the frequency, rate or extent of calcium ion transmembrane transport.	tmpzr1t_l9r_go_relaxed.owl	regulation of transmembrane calcium transport|regulation of calcium ion membrane transport					human HRC regulates RYR2 and thus regulates transmembrane transport of calcium from SR to cytosol		rl	2014-07-11T17:09:26Z					biological_process											owl:Class	
GO:0046246	biolink:NamedThing	terpene biosynthetic process	The chemical reactions and pathways resulting in the formation of terpenes, any of a large group of hydrocarbons made up of isoprene units.	tmpzr1t_l9r_go_relaxed.owl	terpene synthesis|terpene biosynthesis|terpene formation|terpene anabolism													biological_process											owl:Class	
GO:0008299	biolink:NamedThing	isoprenoid biosynthetic process	The chemical reactions and pathways resulting in the formation of an isoprenoid compound, isoprene (2-methylbuta-1,3-diene) or compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues.	tmpzr1t_l9r_go_relaxed.owl	polyterpene biosynthesis|polyterpene biosynthetic process|polyisoprenoid biosynthetic process|isoprenoid synthesis|isoprenoid biosynthesis|polyisoprenoid synthesis|isoprenoid formation|polyisoprenoid formation|polyisoprenoid biosynthesis|isoprenoid anabolism|polyisoprenoid anabolism				MetaCyc:POLYISOPRENSYN-PWY							GO:0009241		biological_process											owl:Class	
GO:0045611	biolink:NamedThing	negative regulation of hemocyte differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of hemocyte differentiation.	tmpzr1t_l9r_go_relaxed.owl	downregulation of hemocyte differentiation|negative regulation of arthropod blood cell differentiation|down-regulation of hemocyte differentiation|inhibition of hemocyte differentiation|down regulation of hemocyte differentiation													biological_process											owl:Class	
GO:1905170	biolink:NamedThing	negative regulation of protein localization to phagocytic vesicle	Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to phagocytic vesicle.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of protein localisation to phagocytic vesicle|inhibition of protein localisation to phagosome|down-regulation of protein localization to phagocytic vesicle|down-regulation of protein localization in phagocytic vesicle|downregulation of protein recruitment to phagosome|negative regulation of protein localisation to phagosome|down-regulation of protein localisation to phagosome|down regulation of protein localisation to phagosome|downregulation of protein localisation to phagocytic vesicle|down regulation of protein localization in phagocytic vesicle|downregulation of protein localisation in phagocytic vesicle|down regulation of protein recruitment to phagosome|inhibition of protein localisation in phagocytic vesicle|downregulation of protein localization to phagocytic vesicle|downregulation of protein localization in phagocytic vesicle|inhibition of protein localization to phagocytic vesicle|negative regulation of protein localization in phagocytic vesicle|inhibition of protein recruitment to phagosome|down regulation of protein localisation in phagocytic vesicle|down-regulation of protein recruitment to phagosome|down-regulation of protein localisation to phagocytic vesicle|down-regulation of protein localisation in phagocytic vesicle|down regulation of protein localization to phagocytic vesicle|down regulation of protein localisation to phagocytic vesicle|negative regulation of protein localisation in phagocytic vesicle|inhibition of protein localisation to phagocytic vesicle|negative regulation of protein recruitment to phagosome|downregulation of protein localisation to phagosome|inhibition of protein localization in phagocytic vesicle							bf	2016-05-02T18:38:22Z					biological_process											owl:Class	
GO:0036376	biolink:NamedThing	sodium ion export across plasma membrane	The directed movement of sodium ions from inside of a cell, across the plasma membrane and into the extracellular region.	tmpzr1t_l9r_go_relaxed.owl	sodium export|sodium ion export|sodium ion export from cell							mah	2009-12-16T11:13:55Z			GO:0071436|GO:0098667		biological_process											owl:Class	
GO:1904991	biolink:NamedThing	negative regulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway	Any process that stops, prevents or reduces the frequency, rate or extent of adenylate cyclase-inhibiting dopamine receptor signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway|inhibition of dopamine receptor, adenylyl cyclase inhibiting pathway|inhibition of adenylate cyclase-inhibiting dopamine receptor signaling pathway|down-regulation of inhibition of adenylate cyclase activity by dopamine receptor signaling pathway|down regulation of dopamine receptor, adenylate cyclase inhibiting pathway|downregulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway|down regulation of inhibition of adenylate cyclase activity by dopamine receptor signaling pathway|down regulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway|inhibition of inhibition of adenylate cyclase activity by dopamine receptor signalling pathway|downregulation of inhibition of adenylate cyclase activity by dopamine receptor signalling pathway|downregulation of inhibition of adenylate cyclase activity by dopamine receptor signaling pathway|down regulation of inhibition of adenylate cyclase activity by dopamine receptor signalling pathway|inhibition of dopamine receptor, adenylate cyclase inhibiting pathway|downregulation of dopamine receptor, adenylate cyclase inhibiting pathway|negative regulation of dopamine receptor, adenylyl cyclase inhibiting pathway|down-regulation of dopamine receptor, adenylyl cyclase inhibiting pathway|downregulation of dopamine receptor, adenylyl cyclase inhibiting pathway|negative regulation of dopamine receptor, adenylate cyclase inhibiting pathway|down-regulation of inhibition of adenylate cyclase activity by dopamine receptor signalling pathway|down regulation of dopamine receptor, adenylyl cyclase inhibiting pathway|down-regulation of dopamine receptor, adenylate cyclase inhibiting pathway|negative regulation of inhibition of adenylate cyclase activity by dopamine receptor signalling pathway|inhibition of inhibition of adenylate cyclase activity by dopamine receptor signaling pathway|negative regulation of inhibition of adenylate cyclase activity by dopamine receptor signaling pathway							kmv	2016-02-29T22:42:25Z					biological_process											owl:Class	
GO:1904990	biolink:NamedThing	regulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway	Any process that modulates the frequency, rate or extent of adenylate cyclase-inhibiting dopamine receptor signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	regulation of dopamine receptor, adenylyl cyclase inhibiting pathway|regulation of dopamine receptor, adenylate cyclase inhibiting pathway|regulation of inhibition of adenylate cyclase activity by dopamine receptor signalling pathway|regulation of inhibition of adenylate cyclase activity by dopamine receptor signaling pathway							kmv	2016-02-29T22:42:16Z					biological_process											owl:Class	
GO:0010888	biolink:NamedThing	negative regulation of lipid storage	Any process that decreases the rate, frequency or extent of lipid storage. Lipid storage is the accumulation and maintenance in cells or tissues of lipids, compounds soluble in organic solvents but insoluble or sparingly soluble in aqueous solvents. Lipid reserves can be accumulated during early developmental stages for mobilization and utilization at later stages of development.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1905953	biolink:NamedThing	negative regulation of lipid localization	Any process that stops, prevents or reduces the frequency, rate or extent of lipid localization.	tmpzr1t_l9r_go_relaxed.owl	down regulation of lipid localization|down-regulation of lipid localization|down-regulation of lipid localisation|downregulation of lipid localisation|inhibition of lipid localization|down regulation of lipid localisation|inhibition of lipid localisation|downregulation of lipid localization|negative regulation of lipid localisation							rz	2017-02-21T12:12:41Z					biological_process											owl:Class	
GO:0015216	biolink:NamedThing	purine nucleotide transmembrane transporter activity	Enables the transfer of a purine nucleotide, any compound consisting of a purine nucleoside esterified with (ortho)phosphate, from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:2001277	biolink:NamedThing	negative regulation of leucine biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of leucine biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of leucine synthesis|negative regulation of leucine biosynthesis|negative regulation of leucine anabolism|negative regulation of leucine formation							mcc	2011-12-13T03:13:36Z					biological_process											owl:Class	
GO:2001276	biolink:NamedThing	regulation of leucine biosynthetic process	Any process that modulates the frequency, rate or extent of leucine biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of leucine formation|regulation of leucine anabolism|regulation of leucine biosynthesis|regulation of leucine synthesis							mcc	2011-12-13T03:13:27Z					biological_process											owl:Class	
GO:0000494	biolink:NamedThing	box C/D RNA 3'-end processing	Any process involved in forming the mature 3' end of a box C/D RNA molecule.	tmpzr1t_l9r_go_relaxed.owl	box C/D sRNA 3'-end processing|box C/D RNA 3' end processing|box C/D snoRNA 3'-end processing	https://github.com/geneontology/go-ontology/issues/20416												biological_process											owl:Class	
GO:0034963	biolink:NamedThing	box C/D RNA processing	Any process involved in the conversion of a primary box C/D type small  RNA transcript into a mature box C/D RNA.	tmpzr1t_l9r_go_relaxed.owl	box C/D sRNA processing|box C/D snoRNA processing	https://github.com/geneontology/go-ontology/issues/20416												biological_process											owl:Class	
GO:0120305	biolink:NamedThing	regulation of pigmentation	Any process that modulates the frequency, rate or extent of the deposition or modulates the distribution of coloring matter in an organism.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/20524						krc	2021-02-09T19:37:35Z					biological_process											owl:Class	
GO:2001162	biolink:NamedThing	positive regulation of histone H3-K79 methylation	Any process that activates or increases the frequency, rate or extent of histone H3-K79 methylation.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of histone lysine H3 K79 methylation|positive regulation of histone H3K79me|positive regulation of histone H3 K79 methylation							se	2011-10-25T10:27:10Z					biological_process											owl:Class	
GO:0035388	biolink:NamedThing	positive regulation of Roundabout signaling pathway	Any process that activates or increases the frequency, rate or extent of the Roundabout signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of Roundabout signalling pathway							bf	2010-03-18T02:41:16Z					biological_process											owl:Class	
GO:1904387	biolink:NamedThing	cellular response to L-phenylalanine derivative	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-phenylalanine derivative stimulus.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-06-23T17:56:25Z					biological_process											owl:Class	
GO:1903325	biolink:NamedThing	positive regulation of snoRNA metabolic process	Any process that activates or increases the frequency, rate or extent of snoRNA metabolic process.	tmpzr1t_l9r_go_relaxed.owl	up regulation of snoRNA metabolic process|up-regulation of snoRNA metabolic process|upregulation of snoRNA metabolism|activation of snoRNA metabolism|up-regulation of snoRNA metabolism|up regulation of snoRNA metabolism|upregulation of snoRNA metabolic process|positive regulation of snoRNA metabolism|activation of snoRNA metabolic process							vw	2014-08-18T13:05:33Z					biological_process											owl:Class	
GO:1900304	biolink:NamedThing	negative regulation of laminaritriose transport	Any process that stops, prevents or reduces the frequency, rate or extent of laminaritriose transport.	tmpzr1t_l9r_go_relaxed.owl	down regulation of laminaritriose transport|downregulation of laminaritriose transport|inhibition of laminaritriose transport|down-regulation of laminaritriose transport							tt	2012-04-05T07:57:58Z					biological_process											owl:Class	
GO:0051051	biolink:NamedThing	negative regulation of transport	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	inhibition of transport|downregulation of transport|down regulation of transport|down-regulation of transport													biological_process											owl:Class	
GO:0034575	biolink:NamedThing	4-isopropylaniline dehydrogenase activity	Catalysis of the reaction: 4-isopropylaniline + H2O = 4'-(2-hydroxyisopropyl)phenylaniline + 2 H+ + 2 e-.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0901|EC:1.17.99.-									molecular_function											owl:Class	
GO:0016725	biolink:NamedThing	oxidoreductase activity, acting on CH or CH2 groups	Catalysis of an oxidation-reduction (redox) reaction in which a CH2 group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.	tmpzr1t_l9r_go_relaxed.owl	oxidoreductase activity, acting on CH or CH2 groups, other acceptors				EC:1.17.-.-									molecular_function											owl:Class	
GO:0097350	biolink:NamedThing	neutrophil clearance	The selective elimination of senescent neutrophils from the body by autoregulatory mechanisms.	tmpzr1t_l9r_go_relaxed.owl								pr	2012-06-27T03:53:38Z					biological_process											owl:Class	
GO:0043277	biolink:NamedThing	apoptotic cell clearance	The recognition and removal of an apoptotic cell by a neighboring cell or by a phagocyte.	tmpzr1t_l9r_go_relaxed.owl	efferocytosis|apoptotic cell removal|programmed cell clearance					Note that unlike mammals or Drosophila, C. elegans (and many lower organisms) do not have professional macrophages/phagocytes, instead cell corpses are engulfed by neighboring cells. Cell types that can function as engulfing cells include hypodermal cells, gonadal sheath cells, pharyngeal muscle cells, and intestinal cells.								biological_process											owl:Class	
GO:0099507	biolink:NamedThing	ligand-gated ion channel activity involved in regulation of presynaptic membrane potential	Any ligand-gated ion channel activity, occurring in the presynaptic membrane, that is involved in regulation of presynaptic membrane potential.	tmpzr1t_l9r_go_relaxed.owl	ligand-gated ion channel activity involved in regulation of pre-synaptic membrane potential|ligand-dependent ion channel activity involved in regulation of presynaptic membrane potential|ligand-dependent ion channel activity involved in regulation of pre-synaptic membrane potential|ligand gated ion channel activity involved in regulation of presynaptic membrane potential													molecular_function											owl:Class	
GO:1904060	biolink:NamedThing	negative regulation of locomotor rhythm	Any process that stops, prevents or reduces the frequency, rate or extent of locomotor rhythm.	tmpzr1t_l9r_go_relaxed.owl	down regulation of circadian locomotor activity rhythm|downregulation of locomotor rhythm|inhibition of circadian locomotor activity rhythm|down-regulation of circadian locomotor activity rhythm|down-regulation of locomotor rhythm|inhibition of locomotor rhythm|down regulation of locomotor rhythm|downregulation of circadian locomotor activity rhythm|negative regulation of circadian locomotor activity rhythm							sl	2015-03-18T20:38:58Z					biological_process											owl:Class	
GO:1900145	biolink:NamedThing	regulation of nodal signaling pathway involved in determination of left/right asymmetry	Any process that modulates the frequency, rate or extent of a nodal signaling pathway, where the nodal signaling pathway is involved in determination of left/right asymmetry.	tmpzr1t_l9r_go_relaxed.owl	regulation of nodal signalling pathway involved in determination of left/right asymmetry							bf	2012-03-06T11:00:32Z					biological_process											owl:Class	
GO:1900107	biolink:NamedThing	regulation of nodal signaling pathway	Any process that modulates the frequency, rate or extent of nodal signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	regulation of nodal signalling pathway|regulation of nodal signaling							bf	2012-02-16T03:34:19Z					biological_process											owl:Class	
GO:0030373	biolink:NamedThing	high molecular weight B cell growth factor receptor activity	Combining with a high molecular weight B cell growth factor and transmitting the signal to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	HMW-BCGF receptor|high molecular weight B lymphocyte growth factor receptor activity|high molecular weight B-lymphocyte growth factor receptor activity|high molecular weight B-cell growth factor receptor activity													molecular_function											owl:Class	
GO:0038023	biolink:NamedThing	signaling receptor activity	Receiving a signal and transmitting it in the cell to initiate a change in cell activity. A signal is a physical entity or change in state that is used to transfer information in order to trigger a response.	tmpzr1t_l9r_go_relaxed.owl	receptor activity involved in signal transduction|signalling receptor activity|receptor activity							bf	2011-08-01T02:45:27Z			GO:0019041|GO:0004872		molecular_function											owl:Class	
GO:0055043	biolink:NamedThing	5-oxovalerate dehydrogenase activity	Catalysis of the reaction: 5-oxovalerate + NADP+ + H2O = glutarate + NADPH + H+.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0072105	biolink:NamedThing	ureteric peristalsis	A wavelike sequence of involuntary muscular contraction and relaxation that passes along the ureter, impelling the contents onwards. The ureter is one of a pair of thick-walled tubes that transports urine from the kidney pelvis to the urinary bladder.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-02-10T03:07:54Z					biological_process											owl:Class	
GO:0014849	biolink:NamedThing	ureter smooth muscle contraction	A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the ureter. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The ureter is one of a pair of thick-walled tubes that transports urine from the kidney pelvis to the urinary bladder.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0051872	biolink:NamedThing	sphingosine catabolic process	The chemical reactions and pathways resulting in the breakdown of sphingosine (sphing-4-enine), trans-D-erytho-2-amino-octadec-4-ene-1,3-diol, a long chain amino diol sphingoid base that occurs in most sphingolipids in animal tissues.	tmpzr1t_l9r_go_relaxed.owl	sphing-4-enine catabolism|sphing-4-enine catabolic process|(4E)-sphing-4-enine catabolism|(4E)-sphing-4-enine catabolic process													biological_process											owl:Class	
GO:0046521	biolink:NamedThing	sphingoid catabolic process	The chemical reactions and pathways resulting in the breakdown of sphingoids, any of a class of compounds comprising sphinganine and its homologues and stereoisomers, and derivatives of these compounds.	tmpzr1t_l9r_go_relaxed.owl	sphingoid degradation|sphingoid catabolism|sphingoid breakdown													biological_process											owl:Class	
GO:1904129	biolink:NamedThing	positive regulation of convergent extension involved in somitogenesis	Any process that activates or increases the frequency, rate or extent of convergent extension involved in somitogenesis.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of convergent extension involved in somitogenesis|upregulation of convergent extension involved in somitogenesis|up regulation of convergent extension involved in somitogenesis|activation of convergent extension involved in somitogenesis							dph	2015-04-10T21:13:15Z					biological_process											owl:Class	
GO:1900400	biolink:NamedThing	regulation of iron ion import into cell by regulation of transcription from RNA polymerase II promoter	A regulation of transcription from RNA polymerase II promoter that results in regulation of iron ion import.	tmpzr1t_l9r_go_relaxed.owl	regulation of iron ion transport by regulation of transcription from RNA polymerase II promoter|regulation of iron ion import by regulation of transcription from RNA polymerase II promoter|regulation of iron import by regulation of transcription from RNA polymerase II promoter								2012-04-20T02:34:12Z			GO:1900393		biological_process											owl:Class	
GO:0034581	biolink:NamedThing	4-methyloct-2-enoyl-CoA hydratase activity	Catalysis of the reaction: 4-methyloct-2-enoyl-CoA + H2O = 3-hydroxy-4-methyloctanoyl-CoA.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0925									molecular_function											owl:Class	
GO:2000161	biolink:NamedThing	regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis	Any process that modulates the frequency, rate or extent of planar cell polarity pathway involved in cardiac right atrium morphogenesis.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-10-05T01:05:21Z					biological_process											owl:Class	
GO:2000159	biolink:NamedThing	regulation of planar cell polarity pathway involved in heart morphogenesis	Any process that modulates the frequency, rate or extent of planar cell polarity pathway involved in heart morphogenesis.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-10-05T01:03:22Z					biological_process											owl:Class	
GO:0000962	biolink:NamedThing	positive regulation of mitochondrial RNA catabolic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving catabolism in the mitochondrion of RNA transcribed from the mitochondrial genome.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0070179	biolink:NamedThing	D-serine biosynthetic process	The chemical reactions and pathways resulting in the formation of D-serine, the D-enantiomer of serine, i.e. (2R)-2-amino-3-hydroxypropanoic acid. D-serine is often formed by racemization of L-serine.	tmpzr1t_l9r_go_relaxed.owl	D-serine synthesis|D-serine biosynthesis|D-serine anabolism|D-serine formation													biological_process											owl:Class	
GO:0046437	biolink:NamedThing	D-amino acid biosynthetic process	The chemical reactions and pathways resulting in the formation of D-amino acids, the D-enantiomers of amino acids.	tmpzr1t_l9r_go_relaxed.owl	D-amino acid anabolism|D-amino acid biosynthesis|D-amino acid synthesis|D-amino acid formation													biological_process											owl:Class	
GO:0043300	biolink:NamedThing	regulation of leukocyte degranulation	Any process that modulates the frequency, rate, or extent of leukocyte degranulation.	tmpzr1t_l9r_go_relaxed.owl	regulation of immune cell granule exocytosis|regulation of immune cell degranulation|regulation of leukocyte granule exocytosis|regulation of leucocyte degranulation													biological_process											owl:Class	
GO:0002697	biolink:NamedThing	regulation of immune effector process	Any process that modulates the frequency, rate, or extent of an immune effector process.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0044830	biolink:NamedThing	modulation by host of viral RNA genome replication	A process in which a host organism modulates the frequency, rate or extent of viral RNA genome replication.	tmpzr1t_l9r_go_relaxed.owl	regulation by host of viral RNA genome replication							jl	2014-02-06T11:43:16Z					biological_process											owl:Class	
GO:0044827	biolink:NamedThing	modulation by host of viral genome replication	A process in which a host organism modulates the frequency, rate or extent of viral genome replication.	tmpzr1t_l9r_go_relaxed.owl	regulation by host of viral genome reproduction							jl	2014-02-06T11:26:45Z					biological_process											owl:Class	
GO:0009665	biolink:NamedThing	plastid inheritance	The partitioning of plastids between daughter cells at cell division.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0048308	biolink:NamedThing	organelle inheritance	The partitioning of organelles between daughter cells at cell division.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0010528	biolink:NamedThing	regulation of transposition	Any process that modulates the frequency, rate or extent of transposition. Transposition results in the movement of discrete segments of DNA between nonhomologous sites.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0071063	biolink:NamedThing	sensory perception of wind	The series of events required for an organism to receive sensory mechanical stimulus resulting from air flow, convert it to a molecular signal, and recognize and characterize the signal.	tmpzr1t_l9r_go_relaxed.owl	sensory perception of air flow|perception of wind							mah	2009-11-04T02:40:34Z					biological_process											owl:Class	
GO:0050954	biolink:NamedThing	sensory perception of mechanical stimulus	The series of events required for an organism to receive a sensory mechanical stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.	tmpzr1t_l9r_go_relaxed.owl	perception of mechanical stimulus|chemi-mechanical coupling|mechanosensory perception													biological_process											owl:Class	
GO:0101013	biolink:NamedThing	mechanosensitive voltage-gated sodium channel activity	Enables the transmembrane transfer of a sodium ion by a voltage-gated channel whose activity is modulated in response to mechanical stress. Response to mechanical stress and voltage gating  together is different than the sum of individual responses. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.	tmpzr1t_l9r_go_relaxed.owl	mechanically-modulated voltage-gated sodium channel activity													molecular_function											owl:Class	
GO:0140135	biolink:NamedThing	mechanosensitive cation channel activity	Enables the transmembrane transfer of a cation by a channel that opens in response to a mechanical stress.	tmpzr1t_l9r_go_relaxed.owl	mechanically-gated cation channel activity	https://github.com/geneontology/go-ontology/issues/14588						pg	2017-11-17T12:40:37Z					molecular_function											owl:Class	
GO:0098796	biolink:NamedThing	membrane protein complex	Any protein complex that is part of a membrane.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0051044	biolink:NamedThing	positive regulation of membrane protein ectodomain proteolysis	Any process that activates or increases the frequency, rate or extent of membrane protein ectodomain peptidolysis.	tmpzr1t_l9r_go_relaxed.owl	up regulation of membrane protein ectodomain proteolysis|activation of membrane protein ectodomain proteolysis|stimulation of membrane protein ectodomain proteolysis|up-regulation of membrane protein ectodomain proteolysis|upregulation of membrane protein ectodomain proteolysis													biological_process											owl:Class	
GO:0060043	biolink:NamedThing	regulation of cardiac muscle cell proliferation	Any process that modulates the frequency, rate or extent of cardiac muscle cell proliferation.	tmpzr1t_l9r_go_relaxed.owl	regulation of cardiomyocyte proliferation|regulation of heart muscle cell proliferation													biological_process											owl:Class	
GO:0055021	biolink:NamedThing	regulation of cardiac muscle tissue growth	Any process that modulates the frequency, rate or extent of cardiac muscle growth.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0086102	biolink:NamedThing	adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway involved in negative regulation of heart rate	A G protein-coupled acetylcholine receptor signaling pathway that contributes to an decrease in frequency or rate of heart contraction through inhibition of adenylate cyclase (AC) activity. Binding of acetylcholine to a G protein-coupled (muscarinic) receptor on the surface of the signal-receiving cell results in the activation of an intracellular Gi/o protein. Gi/o inhibits adenylate cyclase to decrease cyclic-AMP (cAMP) levels. Since cAMP binds directly to F-channels to allow an inward flow of sodium (funny current, If current), a reduction in cAMP reduces the funny current to bring about membrane hyperpolarization and a decrease in heart rate.	tmpzr1t_l9r_go_relaxed.owl	muscarinic receptor signalling pathway involved in negative regulation of heart rate by inhibition of If channel|AC-inhibiting muscarinic receptor signaling pathway involved in negative regulation of heart rate|muscarinic receptor signalling pathway involved in negative regulation of heart rate by inhibition of funny current|adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway involved in negative regulation of heart rate|Gi-coupled G-protein coupled acetylcholine receptor signaling pathway involved in negative regulation of heart rate|G-protein coupled acetylcholine receptor signaling pathway involved in negative regulation of heart rate via inhibition of adenylate cyclase activity							bf						biological_process											owl:Class	
GO:0086033	biolink:NamedThing	G protein-coupled acetylcholine receptor signaling pathway involved in negative regulation of heart rate	A G protein-coupled acetylcholine receptor signaling pathway that contributes to a decrease in frequency or rate of heart contraction. Binding of acetylcholine to a G protein-coupled (muscarinic) receptor on the surface of the signal-receiving cell results in the alpha subunit of a coupled G-protein binding to GTP. This results in the separation of the beta-gamma complex from the alpha subunit. Both the alpha subunit, and the beta-gamma complex can continue to signal to bring about membrane hyperpolarization and a reduction in heart rate.	tmpzr1t_l9r_go_relaxed.owl	G-protein coupled acetylcholine receptor signaling pathway involved in negative regulation of heart rate|muscarinic receptor signalling pathway involved in negative regulation of heart rate|M2 receptor signalling pathway involved in negative regulation of heart rate|muscarinic acetylcholine receptor signaling pathway involved in negative regulation of heart rate							tb	2011-11-11T03:11:58Z					biological_process											owl:Class	
GO:0030427	biolink:NamedThing	site of polarized growth	Any part of a cell where non-isotropic growth takes place.	tmpzr1t_l9r_go_relaxed.owl												GO:0030483|GO:0000134		cellular_component											owl:Class	
GO:0000489	biolink:NamedThing	maturation of SSU-rRNA from tetracistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 4.5S-rRNA, 5S-rRNA)	Any process involved in the maturation of a precursor Small SubUnit (SSU) ribosomal RNA (rRNA) molecule into a mature SSU-rRNA molecule from the pre-rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, Large Subunit (LSU) the 4.5S rRNA, and the 5S rRNA in that order from 5' to 3' along the primary transcript.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0048833	biolink:NamedThing	specification of floral organ number	Any process that modulates the number of floral organs formed in a floral whorl.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0048832	biolink:NamedThing	specification of plant organ number	The regionalization process that modulates the quantity of a particular type of plant organ.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0030840	biolink:NamedThing	negative regulation of intermediate filament polymerization	Any process that stops, prevents, or reduces the frequency, rate or extent of intermediate filament polymerization.	tmpzr1t_l9r_go_relaxed.owl	down regulation of intermediate filament polymerization|negative regulation of intermediate filament polymerization and/or depolymerization|downregulation of intermediate filament polymerization|down-regulation of intermediate filament polymerization|inhibition of intermediate filament polymerization					Note that this term was split from 'negative regulation of intermediate filament polymerization and/or depolymerization ; GO:0045825' (sibling term 'negative regulation of intermediate filament depolymerization ; GO:0030843').								biological_process											owl:Class	
GO:0046336	biolink:NamedThing	ethanolamine catabolic process	The chemical reactions and pathways resulting in the breakdown of ethanolamine (2-aminoethanol), an important water-soluble base of phospholipid (phosphatidylethanolamine).	tmpzr1t_l9r_go_relaxed.owl	ethanolamine catabolism|ethanolamine degradation|ethanolamine breakdown													biological_process											owl:Class	
GO:1901161	biolink:NamedThing	primary amino compound catabolic process	The chemical reactions and pathways resulting in the breakdown of primary amino compound.	tmpzr1t_l9r_go_relaxed.owl	primary amino compound degradation|primary amino compound catabolism|primary amino compound breakdown							bf	2012-07-18T04:45:06Z					biological_process											owl:Class	
GO:2001250	biolink:NamedThing	positive regulation of ammonia assimilation cycle	Any process that activates or increases the frequency, rate or extent of ammonia assimilation cycle.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of glutamate metabolic process via glutamine and ammonia|positive regulation of glutamate metabolism via glutamine and ammonia							rl	2011-12-01T10:08:34Z					biological_process											owl:Class	
GO:0045848	biolink:NamedThing	positive regulation of nitrogen utilization	Any process that activates or increases the frequency, rate or extent of nitrogen utilization.	tmpzr1t_l9r_go_relaxed.owl	up regulation of nitrogen utilization|upregulation of nitrogen utilization|stimulation of nitrogen utilization|up-regulation of nitrogen utilization|activation of nitrogen utilization													biological_process											owl:Class	
GO:0046039	biolink:NamedThing	GTP metabolic process	The chemical reactions and pathways involving GTP, guanosine triphosphate.	tmpzr1t_l9r_go_relaxed.owl	GTP metabolism													biological_process											owl:Class	
GO:0009205	biolink:NamedThing	purine ribonucleoside triphosphate metabolic process	The chemical reactions and pathways involving purine ribonucleoside triphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with triphosphate on the sugar.	tmpzr1t_l9r_go_relaxed.owl	purine ribonucleoside triphosphate metabolism													biological_process											owl:Class	
GO:0090330	biolink:NamedThing	regulation of platelet aggregation	Any process that modulates the rate, frequency or extent of platelet aggregation. Platelet aggregation is the adhesion of one platelet to one or more other platelets via adhesion molecules.	tmpzr1t_l9r_go_relaxed.owl								tb	2010-05-14T10:46:08Z					biological_process											owl:Class	
GO:2001062	biolink:NamedThing	xylan binding	Binding to xylan.	tmpzr1t_l9r_go_relaxed.owl								jl	2011-09-14T10:10:04Z					molecular_function											owl:Class	
GO:0030247	biolink:NamedThing	polysaccharide binding	Binding to a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically.	tmpzr1t_l9r_go_relaxed.owl	polysaccharide assembly with MHC class II protein complex											GO:0002506		molecular_function											owl:Class	
GO:1902934	biolink:NamedThing	isopentenol biosynthetic process	The chemical reactions and pathways resulting in the formation of isopentenol.	tmpzr1t_l9r_go_relaxed.owl	isopentenol anabolism|isopentenol biosynthesis|isopentenol synthesis|isopentenol formation							tt	2014-04-24T16:51:42Z					biological_process											owl:Class	
GO:0010946	biolink:NamedThing	regulation of meiotic joint molecule formation	Any process that modulates the frequency, rate or extent of meiotic joint molecule formation. Meiotic joint molecule formation is the conversion of the paired broken DNA and homologous duplex DNA into a four-stranded branched intermediate, known as a joint molecule, formed during meiotic recombination.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-04-27T09:46:23Z					biological_process											owl:Class	
GO:1904592	biolink:NamedThing	positive regulation of protein refolding	Any process that activates or increases the frequency, rate or extent of protein refolding.	tmpzr1t_l9r_go_relaxed.owl	up regulation of heat shock protein activity|upregulation of protein refolding|up-regulation of protein refolding|up-regulation of heat shock protein activity|activation of heat shock protein activity|positive regulation of heat shock protein activity|up regulation of protein refolding|activation of protein refolding|upregulation of heat shock protein activity							sl	2015-08-21T18:11:16Z					biological_process											owl:Class	
GO:0061083	biolink:NamedThing	regulation of protein refolding	Any process that regulates the rate, frequency, or extent of protein refolding. Protein refolding is the process carried out by a cell that restores the biological activity of an unfolded or misfolded protein, using helper proteins such as chaperones.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-04-26T01:07:54Z					biological_process											owl:Class	
GO:0070856	biolink:NamedThing	myosin VI light chain binding	Binding to a light chain of a myosin VI complex.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-08-13T01:46:13Z					molecular_function											owl:Class	
GO:0032027	biolink:NamedThing	myosin light chain binding	Binding to a light chain of a myosin complex.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0051590	biolink:NamedThing	positive regulation of neurotransmitter transport	Any process that activates or increases the frequency, rate or extent of the directed movement of a neurotransmitter into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	activation of neurotransmitter transport|stimulation of neurotransmitter transport|up-regulation of neurotransmitter transport|upregulation of neurotransmitter transport|up regulation of neurotransmitter transport													biological_process											owl:Class	
GO:0051050	biolink:NamedThing	positive regulation of transport	Any process that activates or increases the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	stimulation of transport|up regulation of transport|activation of transport|up-regulation of transport|upregulation of transport													biological_process											owl:Class	
GO:0042216	biolink:NamedThing	phenanthrene catabolic process	The chemical reactions and pathways resulting in the breakdown of phenanthrene, a tricyclic aromatic hydrocarbon.	tmpzr1t_l9r_go_relaxed.owl	phenanthrene degradation|phenanthrene breakdown|phenanthrene catabolism				UM-BBD_pathwayID:phe									biological_process											owl:Class	
GO:0005885	biolink:NamedThing	Arp2/3 protein complex	A stable protein complex that contains two actin-related proteins, Arp2 and Arp3, and five novel proteins (ARPC1-5), and functions in the nucleation of branched actin filaments.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0097058	biolink:NamedThing	CRLF-CLCF1 complex	A heterodimeric protein complex that is composed of cardiotrophin-like cytokine factor 1 (product of the CLCF1 gene) and cytokine receptor-like factor 1 (product of the CRLF gene) and is secreted into the extracellular space. The CRLF-CLCF1 complex is a ligand for the ciliary neurotrophic factor (CNTF) receptor complex.	tmpzr1t_l9r_go_relaxed.owl	CLF-CLC complex							pr	2011-05-26T10:37:55Z					cellular_component											owl:Class	
GO:0019574	biolink:NamedThing	sucrose catabolic process via 3'-ketosucrose	The chemical reactions and pathways resulting in the breakdown of sucrose, which proceeds via the conversion of sucrose to 3'-ketosucrose. 3'-ketosucrose is hydrolyzed to 3-ketoglucose and fructose, and the 3-ketoglucose is then be converted to glucose.	tmpzr1t_l9r_go_relaxed.owl	sucrose catabolism, using glucoside 3-dehydrogenase|sucrose catabolic process to D-glucose|sucrose breakdown, using glucoside 3-dehydrogenase|sucrose catabolic process, using glucoside 3-dehydrogenase|sucrose degradation, using glucoside 3-dehydrogenase				MetaCyc:SUCROSEUTIL2-PWY									biological_process											owl:Class	
GO:0033263	biolink:NamedThing	CORVET complex	A multimeric protein complex that acts as an endosomal tethering complex (CORVET = class C core vacuole/endosome tethering) by cooperating with Rab GTPases to capture endosomal vesicles and trap them prior to the action of SNAREs; the complex is involved in endo-lysosomal biogenesis and required for transport between endosome and vacuole. The Saccharomyces cerevisiae complex contains Vps8p, Vps3p, Pep5p, Vps16p, Pep3p, and Vps33p.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0099023	biolink:NamedThing	vesicle tethering complex	Any protein complex that plays a role in vesicle tethering.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0034773	biolink:NamedThing	histone H4-K20 trimethylation	The modification of histone H4 by addition of three methyl groups to lysine at position 20 of the histone.	tmpzr1t_l9r_go_relaxed.owl	histone lysine H4 K20 trimethylation|histone H4 K20 trimethylation													biological_process											owl:Class	
GO:0018023	biolink:NamedThing	peptidyl-lysine trimethylation	The methylation of peptidyl-lysine to form peptidyl-N6,N6,N6-trimethyl-L-lysine.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0074									biological_process											owl:Class	
GO:0090180	biolink:NamedThing	positive regulation of thiamine biosynthetic process	Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of thiamine.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of thiamin biosynthetic process							tb	2009-12-18T10:30:07Z					biological_process											owl:Class	
GO:0002033	biolink:NamedThing	angiotensin-mediated vasodilation involved in regulation of systemic arterial blood pressure	The process that increases the diameter of a blood vessel via the renin-angiotensin system.	tmpzr1t_l9r_go_relaxed.owl	vasodilation by angiotensin involved in regulation of systemic arterial blood pressure													biological_process											owl:Class	
GO:0042311	biolink:NamedThing	vasodilation	An increase in the internal diameter of blood vessels, especially arterioles or capillaries, due to relaxation of smooth muscle cells that line the vessels, and usually resulting in a decrease in blood pressure.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of blood vessel size|vasodilatation	https://github.com/geneontology/go-ontology/issues/12253			Wikipedia:Vasodilation							GO:0045909		biological_process											owl:Class	
GO:0110073	biolink:NamedThing	regulation of apical constriction involved in ventral furrow formation	Any process that modulates the frequency, rate or extent of apical constriction involved in ventral furrow formation.	tmpzr1t_l9r_go_relaxed.owl								kmv	2017-12-06T17:30:29Z					biological_process											owl:Class	
GO:1903115	biolink:NamedThing	regulation of actin filament-based movement	Any process that modulates the frequency, rate or extent of actin filament-based movement.	tmpzr1t_l9r_go_relaxed.owl								al	2014-06-12T16:55:57Z					biological_process											owl:Class	
GO:2000405	biolink:NamedThing	negative regulation of T cell migration	Any process that stops, prevents or reduces the frequency, rate or extent of T cell migration.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of T-lymphocyte migration|negative regulation of T-cell migration|negative regulation of T lymphocyte migration							mah	2011-02-23T10:48:52Z					biological_process											owl:Class	
GO:2000774	biolink:NamedThing	positive regulation of cellular senescence	Any process that activates or increases the frequency, rate or extent of cellular senescence.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-06-22T01:57:12Z					biological_process											owl:Class	
GO:0048243	biolink:NamedThing	norepinephrine secretion	The regulated release of norepinephrine by a cell. Norepinephrine is a catecholamine and it acts as a hormone and as a neurotransmitter of most of the sympathetic nervous system.	tmpzr1t_l9r_go_relaxed.owl	noradrenaline secretion													biological_process											owl:Class	
GO:0015874	biolink:NamedThing	norepinephrine transport	The directed movement of norepinephrine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Norepinephrine (3,4-dihydroxyphenyl-2-aminoethanol) is a hormone secreted by the adrenal medulla and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts of the CNS. It is also the biosynthetic precursor of epinephrine.	tmpzr1t_l9r_go_relaxed.owl	levarterenol transport|noradrenaline transport													biological_process											owl:Class	
GO:0036101	biolink:NamedThing	leukotriene B4 catabolic process	The chemical reactions and pathways resulting in the breakdown of leukotriene B4, a leukotriene composed of (6Z,8E,10E,14Z)-eicosatetraenoic acid having (5S)- and (12R)-hydroxy substituents.	tmpzr1t_l9r_go_relaxed.owl	leukotriene B4 degradation|leukotriene B4 catabolism|leukotriene B4 breakdown|LTB4 catabolism							bf	2012-01-27T01:26:24Z					biological_process											owl:Class	
GO:0036102	biolink:NamedThing	leukotriene B4 metabolic process	The chemical reactions and pathways involving leukotriene B4, a leukotriene composed of (6Z,8E,10E,14Z)-eicosatetraenoic acid having (5S)- and (12R)-hydroxy substituents.	tmpzr1t_l9r_go_relaxed.owl	LTB4 metabolism							bf	2012-01-27T01:39:43Z					biological_process											owl:Class	
GO:2000216	biolink:NamedThing	positive regulation of proline metabolic process	Any process that activates or increases the frequency, rate or extent of proline metabolic process.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of proline metabolism							mah	2010-11-03T02:45:27Z					biological_process											owl:Class	
GO:0031963	biolink:NamedThing	cortisol receptor activity	Combining with cortisol and transmitting the signal within the cell to trigger a change in cell activity or function.	tmpzr1t_l9r_go_relaxed.owl						For cortisol receptors that act in the nucleus to regulate transcription, consider also annotating to the terms: ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity ; GO:0038049' or ligand-activated RNA polymerase II transcription factor binding transcription factor activity ; GO:0038049'.								molecular_function											owl:Class	
GO:0004883	biolink:NamedThing	glucocorticoid receptor activity	Combining with a glucocorticoid and transmitting the signal within the cell trigger a change in cell activity or function.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0061796	biolink:NamedThing	membrane addition at site of mitotic cytokinesis	A mitotic cell cycle process involved in the net addition of membrane at the site of cytokinesis; includes vesicle recruitment and fusion, local lipid synthesis and insertion.	tmpzr1t_l9r_go_relaxed.owl								dph	2016-10-05T12:06:11Z					biological_process											owl:Class	
GO:2000362	biolink:NamedThing	negative regulation of prostaglandin-E synthase activity	Any process that stops, prevents or reduces the frequency, rate or extent of prostaglandin-E synthase activity.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of Prostaglandin-H(2) E-isomerase activity|negative regulation of prostaglandin R-prostaglandin E isomerase activity|negative regulation of prostaglandin endoperoxide E2 isomerase activity|negative regulation of prostaglandin H-E isomerase activity|negative regulation of PGE2 isomerase activity|negative regulation of PGH-PGE isomerase activity|negative regulation of prostaglandin endoperoxide E isomerase activity|negative regulation of PGE isomerase activity|negative regulation of endoperoxide isomerase activity|negative regulation of prostaglandin-H2 E-isomerase activity|negative regulation of (5Z,13E)-(15S)-9alpha,11alpha-epidioxy-15-hydroxyprosta-5,13-dienoate E-isomerase activity							bf	2011-02-03T04:05:39Z					biological_process											owl:Class	
GO:2000361	biolink:NamedThing	regulation of prostaglandin-E synthase activity	Any process that modulates the frequency, rate or extent of prostaglandin-E synthase activity.	tmpzr1t_l9r_go_relaxed.owl	regulation of prostaglandin endoperoxide E2 isomerase activity|regulation of prostaglandin-H2 E-isomerase activity|regulation of PGE isomerase activity|regulation of PGH-PGE isomerase activity|regulation of PGE2 isomerase activity|regulation of prostaglandin endoperoxide E isomerase activity|regulation of (5Z,13E)-(15S)-9alpha,11alpha-epidioxy-15-hydroxyprosta-5,13-dienoate E-isomerase activity|regulation of endoperoxide isomerase activity|regulation of Prostaglandin-H(2) E-isomerase activity|regulation of prostaglandin R-prostaglandin E isomerase activity|regulation of prostaglandin H-E isomerase activity							bf	2011-02-03T04:05:35Z					biological_process											owl:Class	
GO:0071225	biolink:NamedThing	cellular response to muramyl dipeptide	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a muramyl dipeptide stimulus. Muramyl dipeptide is derived from peptidoglycan.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-12-03T01:41:23Z					biological_process											owl:Class	
GO:1901653	biolink:NamedThing	cellular response to peptide	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide stimulus.	tmpzr1t_l9r_go_relaxed.owl								pr	2012-11-20T09:45:19Z					biological_process											owl:Class	
GO:0102193	biolink:NamedThing	protein-ribulosamine 3-kinase activity	Catalysis of the reaction: ATP + a [protein]-N6-D-ribulosyl-L-lysine <=> ADP + a [protein]-N6-(3-O-phospho-D-ribulosyl)-L-lysine.	tmpzr1t_l9r_go_relaxed.owl					RHEA:48432|EC:2.7.1.172|MetaCyc:RXN-12003									molecular_function											owl:Class	
GO:0009636	biolink:NamedThing	response to toxic substance	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a toxic stimulus.	tmpzr1t_l9r_go_relaxed.owl	toxin resistance|detoxification response|toxin susceptibility/resistance													biological_process											owl:Class	
GO:0034671	biolink:NamedThing	retinoic acid receptor signaling pathway involved in pronephros anterior/posterior pattern specification	The series of molecular signals generated as a consequence of a retinoic acid receptor binding to one of its physiological ligands that results in the spatial identity of regions along the anterior-posterior axis of the pronephros.	tmpzr1t_l9r_go_relaxed.owl	retinoic acid receptor signalling pathway involved in pronephros anterior-posterior patterning|retinoic acid receptor signaling pathway involved in pronephric kidney anterior/posterior pattern specification													biological_process											owl:Class	
GO:0048384	biolink:NamedThing	retinoic acid receptor signaling pathway	The series of molecular signals generated as a consequence of a retinoic acid receptor binding to one of its physiological ligands.	tmpzr1t_l9r_go_relaxed.owl	RAR signaling pathway|retinoic acid receptor signalling pathway													biological_process											owl:Class	
GO:0010764	biolink:NamedThing	negative regulation of fibroblast migration	Any process that decreases the rate, frequency or extent of fibroblast cell migration. Fibroblast cell migration is accomplished by extension and retraction of a pseudopodium.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of fibroblast cell migration													biological_process											owl:Class	
GO:0010762	biolink:NamedThing	regulation of fibroblast migration	Any process that modulates the rate, frequency or extent of fibroblast cell migration. Fibroblast cell migration is accomplished by extension and retraction of a pseudopodium.	tmpzr1t_l9r_go_relaxed.owl	regulation of fibroblast cell migration													biological_process											owl:Class	
GO:0000179	biolink:NamedThing	rRNA (adenine-N6,N6-)-dimethyltransferase activity	Catalysis of the dimethylation of two adjacent adenine residues in a rRNA, using S-adenosyl-L-methionine as a methyl donor.	tmpzr1t_l9r_go_relaxed.owl	dimethyladenosine transferase activity|18S rRNA dimethylase activity|S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase activity	https://github.com/geneontology/go-ontology/issues/14459			Reactome:R-HSA-6793066|Reactome:R-HSA-6790994							GO:0043790		molecular_function											owl:Class	
GO:0003028	biolink:NamedThing	regulation of systemic arterial blood pressure by aortic body chemoreceptor signaling	The process that modulates blood pressure by the action of chemoreceptors found in the aortic bodies and their resultant modulation of the vasomotor center. Chemoreceptors respond to oxygen, carbon dioxide and hydrogen ions.	tmpzr1t_l9r_go_relaxed.owl	regulation of systemic arterial blood pressure by aortic body chemoreceptor signalling|aortic body chemoreceptor response to lowering of systemic arterial blood pressure|aortic body chemoreceptor regulation of systemic arterial blood pressure													biological_process											owl:Class	
GO:0001979	biolink:NamedThing	regulation of systemic arterial blood pressure by chemoreceptor signaling	The process that modulates blood pressure by the action of chemoreceptors found in the carotid and aortic bodies and their resultant modulation of the vasomotor center. Chemoreceptors respond to oxygen, carbon dioxide and hydrogen ions.	tmpzr1t_l9r_go_relaxed.owl	regulation of systemic arterial blood pressure by chemoreceptor signalling|chemoreceptor regulation of systemic arterial blood pressure|chemoreceptor control of blood pressure													biological_process											owl:Class	
GO:0034166	biolink:NamedThing	toll-like receptor 10 signaling pathway	Any series of molecular signals generated as a consequence of binding to toll-like receptor 10.	tmpzr1t_l9r_go_relaxed.owl	TLR10 signaling pathway|toll-like receptor 10 signalling pathway													biological_process											owl:Class	
GO:0015026	biolink:NamedThing	coreceptor activity	Combining with an extracellular or intracellular messenger, and in cooperation with a nearby primary receptor, initiating a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	coreceptor, soluble ligand activity|coreceptor, insoluble ligand activity											GO:0015028|GO:0015027		molecular_function											owl:Class	
GO:0043247	biolink:NamedThing	telomere maintenance in response to DNA damage	Any process that occur in response to the presence of critically short or damaged telomeres.	tmpzr1t_l9r_go_relaxed.owl	DNA damage response, telomere maintenance													biological_process											owl:Class	
GO:0000723	biolink:NamedThing	telomere maintenance	Any process that contributes to the maintenance of proper telomeric length and structure by affecting and monitoring the activity of telomeric proteins, the length of telomeric DNA and the replication and repair of the DNA. These processes includes those that shorten, lengthen, replicate and repair the telomeric DNA sequences.	tmpzr1t_l9r_go_relaxed.owl	regulation of telomere length													biological_process											owl:Class	
GO:1904912	biolink:NamedThing	positive regulation of establishment of RNA localization to telomere	Any process that activates or increases the frequency, rate or extent of establishment of RNA localization to telomere.	tmpzr1t_l9r_go_relaxed.owl	up regulation of establishment of RNA localisation to telomere|up-regulation of establishment of RNA localization to telomere|up-regulation of establishment of RNA localisation to telomere|upregulation of establishment of RNA localisation to telomere|activation of establishment of RNA localization to telomere|activation of establishment of RNA localisation to telomere|upregulation of establishment of RNA localization to telomere|positive regulation of establishment of RNA localisation to telomere|up regulation of establishment of RNA localization to telomere							rph	2016-01-19T10:34:35Z					biological_process											owl:Class	
GO:0046604	biolink:NamedThing	positive regulation of mitotic centrosome separation	Any process that activates or increases the frequency, rate or extent of centrosome separation.	tmpzr1t_l9r_go_relaxed.owl	upregulation of mitotic centrosome separation|up-regulation of mitotic centrosome separation|up regulation of mitotic centrosome separation|activation of mitotic centrosome separation|stimulation of mitotic centrosome separation													biological_process											owl:Class	
GO:0090068	biolink:NamedThing	positive regulation of cell cycle process	Any process that increases the rate, frequency or extent of a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-09-09T11:39:52Z					biological_process											owl:Class	
GO:0030714	biolink:NamedThing	anterior/posterior axis specification, follicular epithelium	Polarization of the follicle cells of an insect ovary along the anterior/posterior axis.	tmpzr1t_l9r_go_relaxed.owl	anterior/posterior axis determination, follicular epithelium													biological_process											owl:Class	
GO:1904915	biolink:NamedThing	positive regulation of establishment of protein-containing complex localization to telomere	Any process that activates or increases the frequency, rate or extent of establishment of the localization of a protein-containing macromolecular complex to a telomere.	tmpzr1t_l9r_go_relaxed.owl	up regulation of establishment of macromolecular complex localization to telomere|up regulation of establishment of macromolecular complex localisation to telomere|upregulation of establishment of macromolecular complex localisation to telomere|positive regulation of establishment of macromolecular complex localisation to telomere|positive regulation of establishment of macromolecular complex localization to telomere|activation of establishment of macromolecular complex localization to telomere|up-regulation of establishment of macromolecular complex localization to telomere|up-regulation of establishment of macromolecular complex localisation to telomere|upregulation of establishment of macromolecular complex localization to telomere|activation of establishment of macromolecular complex localisation to telomere							rph	2016-01-19T10:38:36Z					biological_process											owl:Class	
GO:0015515	biolink:NamedThing	citrate:succinate antiporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: citrate(out) + succinate(in) = citrate(in) + succinate(out).	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0015301	biolink:NamedThing	anion:anion antiporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: anion A(out) + anion B(in) = anion A(in) + anion B(out).	tmpzr1t_l9r_go_relaxed.owl	anion exchanger activity|bicarbonate:chloride antiporter				Reactome:R-HSA-561041							GO:0015384|GO:0015380		molecular_function											owl:Class	
GO:0048379	biolink:NamedThing	positive regulation of lateral mesodermal cell fate specification	Any process that activates or increases the frequency, rate or extent of lateral mesoderm cell fate specification.	tmpzr1t_l9r_go_relaxed.owl	up regulation of lateral mesodermal cell fate specification|upregulation of lateral mesodermal cell fate specification|stimulation of lateral mesodermal cell fate specification|up-regulation of lateral mesodermal cell fate specification|activation of lateral mesodermal cell fate specification|positive regulation of lateral plate mesodermal cell fate specification													biological_process											owl:Class	
GO:0048378	biolink:NamedThing	regulation of lateral mesodermal cell fate specification	Any process that modulates the frequency, rate or extent of lateral mesoderm cell fate specification.	tmpzr1t_l9r_go_relaxed.owl	regulation of lateral plate mesodermal cell fate specification													biological_process											owl:Class	
GO:1905914	biolink:NamedThing	positive regulation of calcium ion export across plasma membrane	Any process that activates or increases the frequency, rate or extent of calcium ion export across the plasma membrane.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of calcium ion export from cell|positive regulation of calcium ion efflux from cell|positive regulation of calcium ion export from cell|activation of calcium ion export from cell|activation of calcium ion efflux from cell|upregulation of calcium ion efflux from cell|upregulation of calcium ion export from cell|up regulation of calcium ion export from cell|up-regulation of calcium ion efflux from cell|up regulation of calcium ion efflux from cell							rph	2017-02-07T13:20:56Z					biological_process											owl:Class	
GO:1904427	biolink:NamedThing	positive regulation of calcium ion transmembrane transport	Any process that activates or increases the frequency, rate or extent of calcium ion transmembrane transport.	tmpzr1t_l9r_go_relaxed.owl	up regulation of calcium ion membrane transport|activation of calcium ion transmembrane transport|positive regulation of calcium ion membrane transport|upregulation of calcium ion transmembrane transport|activation of calcium ion membrane transport|up-regulation of calcium ion transmembrane transport|positive regulation of transmembrane calcium transport|upregulation of calcium ion membrane transport|up regulation of calcium ion transmembrane transport|upregulation of transmembrane calcium transport|activation of transmembrane calcium transport|up regulation of transmembrane calcium transport|up-regulation of calcium ion membrane transport|up-regulation of transmembrane calcium transport							sl	2015-07-02T20:44:25Z					biological_process											owl:Class	
GO:1904785	biolink:NamedThing	regulation of asymmetric protein localization involved in cell fate determination	Any process that modulates the frequency, rate or extent of asymmetric protein localization involved in cell fate determination.	tmpzr1t_l9r_go_relaxed.owl	regulation of asymmetric protein localisation involved in cell fate determination|regulation of asymmetric protein localization involved in cell fate commitment|regulation of cell fate commitment, asymmetric protein localization|regulation of asymmetric protein localization resulting in cell fate commitment					wrm-1 in C. Elegans (Q10953) in PMID:17476329 (IMP)		es	2015-11-03T12:11:06Z					biological_process											owl:Class	
GO:2000453	biolink:NamedThing	negative regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation	Any process that stops, prevents or reduces the frequency, rate or extent of CD8-positive, alpha-beta cytotoxic T cell extravasation.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-03-04T10:45:20Z					biological_process											owl:Class	
GO:2000450	biolink:NamedThing	negative regulation of CD8-positive, alpha-beta T cell extravasation	Any process that stops, prevents or reduces the frequency, rate or extent of CD8-positive, alpha-beta T cell extravasation.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-03-04T10:41:43Z					biological_process											owl:Class	
GO:0085044	biolink:NamedThing	disassembly by symbiont of host cuticle	The process in which a symbiont organism effects a breakdown of the host organism cuticle. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	catabolism of host cuticle|degradation of host cuticle							jl	2010-07-27T01:08:15Z					biological_process											owl:Class	
GO:0052111	biolink:NamedThing	modification by symbiont of host structure	The process in which an organism effects a change in an anatomical part or cellular component of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1900024	biolink:NamedThing	regulation of substrate adhesion-dependent cell spreading	Any process that modulates the frequency, rate or extent of substrate adhesion-dependent cell spreading.	tmpzr1t_l9r_go_relaxed.owl	regulation of cell spreading during cell substrate adhesion|regulation of substrate adhesion dependent cell spreading							yaf	2012-01-12T05:00:39Z					biological_process											owl:Class	
GO:0098948	biolink:NamedThing	intrinsic component of postsynaptic specialization membrane	The component of the postsynaptic specialization membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.	tmpzr1t_l9r_go_relaxed.owl	intrinsic to postsynaptic specialization membrane													cellular_component											owl:Class	
GO:0098936	biolink:NamedThing	intrinsic component of postsynaptic membrane	The component of the postsynaptic membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.	tmpzr1t_l9r_go_relaxed.owl	intrinsic to postsynaptic membrane													cellular_component											owl:Class	
GO:2000843	biolink:NamedThing	regulation of testosterone secretion	Any process that modulates the frequency, rate or extent of testosterone secretion.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-07-26T08:42:29Z					biological_process											owl:Class	
GO:0046883	biolink:NamedThing	regulation of hormone secretion	Any process that modulates the frequency, rate or extent of the regulated release of a hormone from a cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0045057	biolink:NamedThing	cisternal progression	The process that results in the physical movement of a new cis-Golgi stack from the cis-position, nearest the endoplasmic reticulum (ER), to the trans position, farthest from the ER, successively becoming first a medial-Golgi cisterna and then a trans-Golgi cisterna.	tmpzr1t_l9r_go_relaxed.owl	cisternal maturation													biological_process											owl:Class	
GO:0006891	biolink:NamedThing	intra-Golgi vesicle-mediated transport	The directed movement of substances within the Golgi, mediated by small transport vesicles. These either fuse with the cis-Golgi or with each other to form the membrane stacks known as the cis-Golgi reticulum (network).	tmpzr1t_l9r_go_relaxed.owl	intra-Golgi transport													biological_process											owl:Class	
GO:0060085	biolink:NamedThing	smooth muscle relaxation of the bladder outlet	A process in which the extent of smooth muscle contraction is reduced in the bladder outlet that contributes to the expulsion of urine from the body.	tmpzr1t_l9r_go_relaxed.owl	synaptic transmission involved in urination													biological_process											owl:Class	
GO:0044557	biolink:NamedThing	relaxation of smooth muscle	A process in which the extent of smooth muscle contraction is reduced. Smooth muscle differs from striated muscle in the much higher actin/myosin ratio, the absence of conspicuous sarcomeres and the ability to contract to a much smaller fraction of its resting length.	tmpzr1t_l9r_go_relaxed.owl	smooth muscle relaxation							jl	2012-04-05T02:42:28Z					biological_process											owl:Class	
GO:0061286	biolink:NamedThing	mesonephric capsule morphogenesis	The process in which the anatomical structures of the mesonephric capsule are generated and organized. The mesonephric capsule is the tough fibrous layer surrounding the mesonephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-09-02T01:53:31Z					biological_process											owl:Class	
GO:0072128	biolink:NamedThing	renal capsule morphogenesis	The process in which the anatomical structures of the renal capsule are generated and organized. The renal capsule is the tough fibrous layer surrounding the kidney, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage. During development, it comprises a single layer of flattened cells that lie just above the cortical stroma and the condensed mesenchyme of the nephrogenic zone. It is in this region that the early stages of nephron induction and formation of new generations ureteric bud branches occur, as the kidney expands.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-02-22T02:06:19Z					biological_process											owl:Class	
GO:2000404	biolink:NamedThing	regulation of T cell migration	Any process that modulates the frequency, rate or extent of T cell migration.	tmpzr1t_l9r_go_relaxed.owl	regulation of T lymphocyte migration|regulation of T-lymphocyte migration|regulation of T-cell migration							mah	2011-02-23T10:48:24Z					biological_process											owl:Class	
GO:0051512	biolink:NamedThing	positive regulation of unidimensional cell growth	Any process that activates or increases the frequency, rate or extent of unidimensional cell growth, the process in which a cell irreversibly increases in size in one [spatial] dimension or along one axis.	tmpzr1t_l9r_go_relaxed.owl	stimulation of unidimensional cell growth|positive regulation of cell elongation|up regulation of unidimensional cell growth|up-regulation of unidimensional cell growth|upregulation of unidimensional cell growth|activation of unidimensional cell growth													biological_process											owl:Class	
GO:0046882	biolink:NamedThing	negative regulation of follicle-stimulating hormone secretion	Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of follicle-stimulating hormone.	tmpzr1t_l9r_go_relaxed.owl	downregulation of follicle-stimulating hormone secretion|down-regulation of follicle-stimulating hormone secretion|negative regulation of follicle stimulating hormone secretion|down regulation of follicle-stimulating hormone secretion|inhibition of follicle-stimulating hormone secretion													biological_process											owl:Class	
GO:0045850	biolink:NamedThing	positive regulation of nurse cell apoptotic process	Any process that activates or increases the frequency, rate or extent of nurse cell apoptotic process.	tmpzr1t_l9r_go_relaxed.owl	stimulation of nurse cell apoptosis|up regulation of nurse cell apoptosis|positive regulation of nurse cell apoptosis|up-regulation of nurse cell apoptosis|activation of nurse cell apoptosis|upregulation of nurse cell apoptosis													biological_process											owl:Class	
GO:1900776	biolink:NamedThing	fumiquinazoline A metabolic process	The chemical reactions and pathways involving fumiquinazoline A.	tmpzr1t_l9r_go_relaxed.owl	fumiquinazoline A metabolism							di	2012-06-04T09:29:58Z					biological_process											owl:Class	
GO:1900773	biolink:NamedThing	fumiquinazoline metabolic process	The chemical reactions and pathways involving fumiquinazoline.	tmpzr1t_l9r_go_relaxed.owl	fumiquinazolines metabolism|fumiquinazoline metabolism|fumiquinazolines metabolic process							di	2012-06-04T09:29:22Z					biological_process											owl:Class	
GO:0010269	biolink:NamedThing	response to selenium ion	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from selenium ion.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:2000045	biolink:NamedThing	regulation of G1/S transition of mitotic cell cycle	Any signalling pathway that modulates the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G1 phase to S phase of the mitotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl						Note that this process is usually achieved by the regulation of the G1 cyclin-dependent protein kinase, consider annotating to the child term 'regulation of cyclin-dependent protein kinase activity involved in G1/S ; GO:0031657'.		tb	2010-08-19T09:10:56Z					biological_process											owl:Class	
GO:1902806	biolink:NamedThing	regulation of cell cycle G1/S phase transition	Any signalling pathway that modulates the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G1 phase to S phase of the cell cycle.	tmpzr1t_l9r_go_relaxed.owl								jl	2014-03-26T16:36:14Z					biological_process											owl:Class	
GO:0031950	biolink:NamedThing	negative regulation of glucocorticoid catabolic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glucocorticoids.	tmpzr1t_l9r_go_relaxed.owl	inhibition of glucocorticoid catabolic process|downregulation of glucocorticoid catabolic process|down regulation of glucocorticoid catabolic process|down-regulation of glucocorticoid catabolic process													biological_process											owl:Class	
GO:0080188	biolink:NamedThing	gene silencing by RNA-directed DNA methylation	A small RNA-based epigenetic gene silencing process in which small interfering RNAs (siRNAs) guide DNA methylation to the siRNA-generating genomic loci and other loci that are homologous to the siRNAs for de novo DNA methylation. This results in a heterochromatin assembly, a chromatin conformation that is refractory to transcription. In general this process consists of three phases: biogenesis of siRNAs, scaffold RNA production, and the formation of the guiding complex that recruits de novo DNA methyltransferases to the target loci. Transposable elements are silenced by this mechanism.	tmpzr1t_l9r_go_relaxed.owl	RNA-directed DNA methylation|RdDM	https://github.com/geneontology/go-ontology/issues/19328|https://github.com/geneontology/go-ontology/issues/22047				This process has been shown in plants and in yeasts, but so far has not been detected in vertebrates, organisms that lack RNA-dependent RNA polymerase.		dhl	2012-05-22T02:22:50Z					biological_process											owl:Class	
GO:0140458	biolink:NamedThing	pre-transcriptional gene silencing by RNA	Any gene inactivation (silencing) process mediated by small RNA molecules that occur before the trancription begins.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/19328						pg	2020-04-24T07:19:09Z					biological_process											owl:Class	
GO:0060285	biolink:NamedThing	cilium-dependent cell motility	Cell motility due to the motion of one or more eukaryotic cilia. A eukaryotic cilium is a specialized organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic (plasma) membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole.	tmpzr1t_l9r_go_relaxed.owl	microtubule-based flagellar cell motility|ciliary cell motility|cilium cell motility					Note that we deem eukaryotic cilia and microtubule-based flagella to be equivalent.						GO:0071974		biological_process											owl:Class	
GO:0001539	biolink:NamedThing	cilium or flagellum-dependent cell motility	Cell motility due to movement of eukaryotic cilia or bacterial-type flagella or archaeal-type flagella.	tmpzr1t_l9r_go_relaxed.owl	ciliary/flagellar motility|ciliary or bacterial-type flagellar motility					Note that we deem eukaryotic cilia and microtubule-based flagella to be equivalent, while the bacterial- and archaeal-type flagella have a different structure. The former are microtubule-based structures that lash back and forth and are present only in eukaryotes, while the latter achieve motility by rotation. Bacterial- and archaeal-type flagella are superficially similar but have a different molecular composition and fine structure. These three structures never co-exist in the same organism. Therefore, GO:0001539 'cilium or flagellum-dependent cell motility' is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term. Direct annotations to GO:0001539 'cilium or flagellum-dependent cell motility' may be amended during annotation QC.								biological_process											owl:Class	
GO:0018960	biolink:NamedThing	4-nitrophenol metabolic process	The chemical reactions and pathways involving 4-nitrophenol, a nitroaromatic compound which is used in the production of dyes, leather treatment agents, fungicides and as an intermediate in the production of the insecticide parathion.	tmpzr1t_l9r_go_relaxed.owl	4-nitrophenol metabolism|p-nitrophenol metabolism|p-nitrophenol metabolic process				UM-BBD_pathwayID:nphe									biological_process											owl:Class	
GO:0006235	biolink:NamedThing	dTTP biosynthetic process	The chemical reactions and pathways resulting in the formation of dTTP, deoxyribosylthymine triphosphate.	tmpzr1t_l9r_go_relaxed.owl	dTTP anabolism|dTTP synthesis|dTTP formation|dTTP biosynthesis													biological_process											owl:Class	
GO:1900197	biolink:NamedThing	negative regulation of penicillin biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of penicillin biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	inhibition of penicillin anabolism|downregulation of penicillin biosynthetic process|down regulation of penicillin anabolism|negative regulation of penicillin synthesis|downregulation of penicillin biosynthesis|downregulation of penicillin formation|downregulation of penicillin synthesis|downregulation of penicillin anabolism|inhibition of penicillin biosynthesis|down-regulation of penicillin biosynthesis|inhibition of penicillin formation|negative regulation of penicillin formation|negative regulation of penicillin anabolism|down-regulation of penicillin anabolism|down-regulation of penicillin biosynthetic process|down-regulation of penicillin synthesis|inhibition of penicillin synthesis|inhibition of penicillin biosynthetic process|down regulation of penicillin biosynthesis|down regulation of penicillin biosynthetic process|negative regulation of penicillin biosynthesis|down regulation of penicillin formation|down-regulation of penicillin formation|down regulation of penicillin synthesis							di	2012-03-20T03:56:43Z					biological_process											owl:Class	
GO:2000301	biolink:NamedThing	negative regulation of synaptic vesicle exocytosis	Any process that stops, prevents or reduces the frequency, rate or extent of synaptic vesicle exocytosis.	tmpzr1t_l9r_go_relaxed.owl								dph	2011-01-03T08:21:00Z					biological_process											owl:Class	
GO:0043641	biolink:NamedThing	novobiocin metabolic process	The chemical reactions and pathways involving novobiocin, a coumarin antibiotic produced by the bacterium Gyrasestreptomyces spheroides, that acts by inhibiting DNA gyrase.	tmpzr1t_l9r_go_relaxed.owl	novobiocin metabolism				Wikipedia:Novobiocin									biological_process											owl:Class	
GO:0009804	biolink:NamedThing	coumarin metabolic process	The chemical reactions and pathways involving coumarins, compounds derived from the phenylacrylic skeleton of cinnamic acids.	tmpzr1t_l9r_go_relaxed.owl	coumarin metabolism													biological_process											owl:Class	
GO:0014741	biolink:NamedThing	negative regulation of muscle hypertrophy	Any process that stops, prevents, or reduces the frequency, rate, or extent of muscle hypertrophy.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0042816	biolink:NamedThing	vitamin B6 metabolic process	The chemical reactions and pathways involving any of the vitamin B6 compounds: pyridoxal, pyridoxamine and pyridoxine and the active form, pyridoxal phosphate.	tmpzr1t_l9r_go_relaxed.owl	vitamin B6 metabolism													biological_process											owl:Class	
GO:0006767	biolink:NamedThing	water-soluble vitamin metabolic process	The chemical reactions and pathways involving any of a diverse group of vitamins that are soluble in water.	tmpzr1t_l9r_go_relaxed.owl	water-soluble vitamin metabolism													biological_process											owl:Class	
GO:0098829	biolink:NamedThing	intestinal folate absorption	Uptake of folic into the blood by absorption from the small intestine.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0015884	biolink:NamedThing	folic acid transport	The directed movement of folic acid (pteroylglutamic acid) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Folic acid is widely distributed as a member of the vitamin B complex and is essential for the synthesis of purine and pyrimidines.	tmpzr1t_l9r_go_relaxed.owl	vitamin B9 transport|folate transport|vitamin M transport													biological_process											owl:Class	
GO:1900035	biolink:NamedThing	negative regulation of cellular response to heat	Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to heat.	tmpzr1t_l9r_go_relaxed.owl	down regulation of cellular response to heat|down-regulation of cellular response to heat|inhibition of cellular response to heat stress|inhibition of cellular response to heat|downregulation of cellular response to heat|down-regulation of cellular response to heat stress|negative regulation of cellular response to heat stress|downregulation of cellular response to heat stress|down regulation of cellular response to heat stress							yaf	2012-01-17T09:27:44Z					biological_process											owl:Class	
GO:1900034	biolink:NamedThing	regulation of cellular response to heat	Any process that modulates the frequency, rate or extent of cellular response to heat.	tmpzr1t_l9r_go_relaxed.owl	regulation of cellular response to heat stress							yaf	2012-01-17T09:27:40Z					biological_process											owl:Class	
GO:0019288	biolink:NamedThing	isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway	The chemical reactions and pathways resulting in the formation of isopentenyl diphosphate by the mevalonate-independent pathway. Isopentenyl diphosphate (IPP) is the fundamental unit in isoprenoid biosynthesis and is biosynthesized from pyruvate and glyceraldehyde 3-phosphate via intermediates, including 1-deoxy-D-xylulose 5-phosphate.	tmpzr1t_l9r_go_relaxed.owl	isopentenyl diphosphate biosynthetic process, MEP pathway|mevalonate-independent isopentenyl diphosphate biosynthetic process|isopentenyl diphosphate biosynthetic process, non-mevalonate pathway|isopentenyl diphosphate formation, mevalonate-independent pathway|non-MVA pathway|isopentenyl diphosphate biosynthesis, non-mevalonate pathway|isopentenyl diphosphate biosynthetic process via 1-deoxy-D-xylulose 5-phosphate|isopentenyl diphosphate anabolism, mevalonate-independent pathway|isopentenyl diphosphate biosynthetic process, mevalonate-independent pathway|isopentenyl diphosphate biosynthetic process, mevalonate-independent|mevalonate-independent isopentenyl diphosphate biosynthesis|isopentenyl diphosphate biosynthesis, mevalonate-independent|isopentenyl diphosphate synthesis, mevalonate-independent pathway				MetaCyc:NONMEVIPP-PWY									biological_process											owl:Class	
GO:0006090	biolink:NamedThing	pyruvate metabolic process	The chemical reactions and pathways involving pyruvate, 2-oxopropanoate.	tmpzr1t_l9r_go_relaxed.owl	pyruvate dehydrogenase bypass|pyruvate metabolism				MetaCyc:P41-PWY|Wikipedia:Pyruvic_acid							GO:0006087		biological_process											owl:Class	
GO:0060229	biolink:NamedThing	lipase activator activity	Binds to and increases the activity of a lipase, an enzyme that catalyzes of the hydrolysis of a lipid.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1900362	biolink:NamedThing	positive regulation of pentasaccharide transport	Any process that activates or increases the frequency, rate or extent of pentasaccharide transport.	tmpzr1t_l9r_go_relaxed.owl	up regulation of pentasaccharide transport|up-regulation of pentasaccharide transport|upregulation of pentasaccharide transport|activation of pentasaccharide transport							tt	2012-04-06T02:19:44Z					biological_process											owl:Class	
GO:1900800	biolink:NamedThing	cspyrone B1 metabolic process	The chemical reactions and pathways involving cspyrone B1.	tmpzr1t_l9r_go_relaxed.owl	cspyrone B1 metabolism							di	2012-06-04T09:50:37Z					biological_process											owl:Class	
GO:0071102	biolink:NamedThing	alpha4-beta1 integrin-paxillin complex	A protein complex that consists of an alpha4-beta1 integrin complex bound to paxillin.	tmpzr1t_l9r_go_relaxed.owl	ITGA4-ITGB1-PXN complex							mah	2009-11-06T04:53:22Z					cellular_component											owl:Class	
GO:0034758	biolink:NamedThing	positive regulation of iron ion transport	Any process that activates or increases the frequency, rate or extent of the directed movement of iron ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	upregulation of iron ion transport|activation of iron ion transport|positive regulation of iron transport|up-regulation of iron ion transport|stimulation of iron ion transport|up regulation of iron ion transport													biological_process											owl:Class	
GO:0019029	biolink:NamedThing	helical viral capsid	The protein coat that surrounds the infective nucleic acid in some virus particles; the subunits are arranged to form a protein helix with the genetic material contained within. Tobacco mosaic virus has such a capsid structure.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0019028	biolink:NamedThing	viral capsid	The protein coat that surrounds the infective nucleic acid in some virus particles. It comprises numerous regularly arranged subunits, or capsomeres.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Capsid							GO:0046728		cellular_component											owl:Class	
GO:1905942	biolink:NamedThing	regulation of formation of growth cone in injured axon	Any process that modulates the frequency, rate or extent of formation of growth cone in injured axon.	tmpzr1t_l9r_go_relaxed.owl								rz	2017-02-13T09:09:05Z					biological_process											owl:Class	
GO:1904450	biolink:NamedThing	positive regulation of aspartate secretion	Any process that activates or increases the frequency, rate or extent of aspartate secretion.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of aspartate secretion|upregulation of aspartate secretion|up regulation of aspartate secretion|activation of aspartate secretion							sl	2015-07-07T20:57:10Z					biological_process											owl:Class	
GO:0051217	biolink:NamedThing	molybdenum incorporation via L-aspartyl molybdenum bis(molybdopterin guanine dinucleotide)	The incorporation of molybdenum into a protein via L-aspartyl molybdenum bis(molybdopterin guanine dinucleotide).	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0375									biological_process											owl:Class	
GO:0060789	biolink:NamedThing	hair follicle placode formation	The developmental process in which a hair placode forms. An hair follicle placode is a thickening of the ectoderm that will give rise to the hair follicle bud.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-08-04T12:18:26Z					biological_process											owl:Class	
GO:0060788	biolink:NamedThing	ectodermal placode formation	The developmental process in which an ectodermal placode forms. An ectodermal placode is a thickening of the ectoderm that is the primordium of many structures derived from the ectoderm.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-08-04T12:15:57Z					biological_process											owl:Class	
GO:0060543	biolink:NamedThing	negative regulation of strand invasion	Any process that decreases the rate, frequency or extent of strand invasion. Strand invasion is the process in which the nucleoprotein complex (composed of the broken single-strand DNA and the recombinase) searches and identifies a region of homology in intact duplex DNA. The broken single-strand DNA displaces the like strand and forms Watson-Crick base pairs with its complement, forming a duplex in which each strand is from one of the two recombining DNA molecules.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of D-loop biosynthesis|negative regulation of Rad51-mediated strand invasion|negative regulation of D-loop formation							dph	2009-04-13T01:32:36Z					biological_process											owl:Class	
GO:0008626	biolink:NamedThing	granzyme-mediated apoptotic signaling pathway	A series of molecular signals induced by granzymes which triggers the apoptotic death of a cell. The pathway starts with reception of a granzyme signal, and ends when the execution phase of apoptosis is triggered. Granzymes are serine proteases that are secreted by cytotoxic T cells and natural killer cells to induce apoptosis in target cells.	tmpzr1t_l9r_go_relaxed.owl	induction of apoptosis by granzyme|apoptotic signaling pathway in response to granzyme	http://wiki.geneontology.org/index.php/Apoptosis_Curation_Manual#Other_children_of_apoptotic_signaling_pathway												biological_process											owl:Class	
GO:0047229	biolink:NamedThing	13-hydroxydocosanoate 13-beta-glucosyltransferase activity	Catalysis of the reaction: 13-hydroxydocosanoate + UDP-D-glucose = 13-beta-D-glucosyloxydocosanoate + UDP.	tmpzr1t_l9r_go_relaxed.owl	UDP-glucose:13-hydroxydocosanoic acid glucosyltransferase activity|uridine diphosphoglucose-hydroxydocosanoate glucosyltransferase activity|UDPglucose:13-hydroxydocosanoate 13-beta-D-glucosyltransferase activity|UDP-glucose:13-hydroxydocosanoate 13-beta-D-glucosyltransferase activity|UDP-glucose-13-hydroxydocosanoate glucosyltransferase activity|13-glucosyloxydocosanoate 2'-beta-glucosyltransferase activity				EC:2.4.1.158|MetaCyc:HYDROXYDOCOSANOATE-TRANS-RXN|RHEA:22316									molecular_function											owl:Class	
GO:0019477	biolink:NamedThing	L-lysine catabolic process	The chemical reactions and pathways resulting in the breakdown of L-lysine, the L-enantiomer of (S)-2,6-diaminohexanoic acid.	tmpzr1t_l9r_go_relaxed.owl	L-lysine breakdown|L-lysine degradation|L-lysine catabolism													biological_process											owl:Class	
GO:0046440	biolink:NamedThing	L-lysine metabolic process	The chemical reactions and pathways involving L-lysine, the L-enantiomer of (S)-2,6-diaminohexanoic acid, i.e. (2S)-2,6-diaminohexanoic acid.	tmpzr1t_l9r_go_relaxed.owl	L-lysine metabolism													biological_process											owl:Class	
GO:1902611	biolink:NamedThing	cellular response to N-phenylthiourea	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a N-phenylthiourea stimulus.	tmpzr1t_l9r_go_relaxed.owl								rjd	2014-01-08T01:57:58Z					biological_process											owl:Class	
GO:1901802	biolink:NamedThing	1,5-anhydro-D-fructose catabolic process	The chemical reactions and pathways resulting in the breakdown of 1,5-anhydro-D-fructose.	tmpzr1t_l9r_go_relaxed.owl	1,5-anhydro-D-fructose degradation|1,5-anhydro-D-fructose catabolism|1,5-anhydro-D-fructose breakdown							yaf	2013-01-22T09:56:25Z					biological_process											owl:Class	
GO:0021933	biolink:NamedThing	radial glia guided migration of cerebellar granule cell	The inward migration of postmitotic granule cells along a radial glial cell from the external granule layer to the internal granule cell layer.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0021932	biolink:NamedThing	hindbrain radial glia guided cell migration	The radially directed movement of a cell along radial glial cells in the hindbrain. Radial migration refers to a directed movement from the internal ventricular area to the outer surface of the hindbrain.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0035875	biolink:NamedThing	maintenance of meiotic sister chromatid cohesion, centromeric	The process in which the association between sister chromatids of a replicated chromosome along the length of the centromeric region is maintained as chromosomes condense, attach to the spindle in a bipolar orientation, and congress to the metaphase plate during a meiotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl	maintenance of meiotic sister chromatin cohesion at centromere|maintenance of sister chromatin cohesion at centromere at meiosis I|maintenance of centromeric meiotic sister chromatin cohesion							bf	2011-05-31T09:35:51Z					biological_process											owl:Class	
GO:0034090	biolink:NamedThing	maintenance of meiotic sister chromatid cohesion	The process in which the association between sister chromatids of a replicated chromosome is maintained as chromosomes condense, attach to the spindle in a bipolar orientation, and congress to the metaphase plate during a meiotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0032215	biolink:NamedThing	positive regulation of telomere maintenance via semi-conservative replication	Any process that activates or increases the frequency, rate or extent of the semi-conservative replication of telomeric DNA.	tmpzr1t_l9r_go_relaxed.owl	upregulation of telomere maintenance via semi-conservative replication|up regulation of telomere maintenance via semi-conservative replication|up-regulation of telomere maintenance via semi-conservative replication|stimulation of telomere maintenance via semi-conservative replication|activation of telomere maintenance via semi-conservative replication													biological_process											owl:Class	
GO:0045253	biolink:NamedThing	pyruvate dehydrogenase (lipoamide) phosphatase complex	A complex of a regulatory and catalytic subunit that catalyzes the dephosphorylation and concomitant reactivation of the alpha subunit of the E1 component of the pyruvate dehydrogenase complex.	tmpzr1t_l9r_go_relaxed.owl						See also the cellular component term 'cytosolic pyruvate dehydrogenase complex ; GO:0045250'.								cellular_component											owl:Class	
GO:0015234	biolink:NamedThing	thiamine transmembrane transporter activity	Enables the transfer of thiamine from one side of a membrane to the other. Thiamine is vitamin B1, a water soluble vitamin present in fresh vegetables and meats, especially liver.	tmpzr1t_l9r_go_relaxed.owl	thiamin uptake transporter activity|vitamin B1 transporter activity|thiamin permease activity|thiamine permease activity|thiamin transmembrane transporter activity|thiamine uptake transmembrane transporter activity				RHEA:34919|Reactome:R-HSA-199626							GO:0015403|GO:0015402		molecular_function											owl:Class	
GO:1904103	biolink:NamedThing	regulation of convergent extension involved in gastrulation	Any process that modulates the frequency, rate or extent of convergent extension involved in gastrulation.	tmpzr1t_l9r_go_relaxed.owl								dph	2015-04-01T11:17:05Z					biological_process											owl:Class	
GO:0015976	biolink:NamedThing	carbon utilization	A series of processes that forms an integrated mechanism by which a cell or an organism detects the depletion of primary carbon sources and then activates genes to scavenge the last traces of the primary carbon source and to transport and metabolize alternative carbon sources such as carbon dioxide or carbonic acid. The utilization process begins when the cell or organism detects carbon levels, includes the activation of genes whose products detect, transport or metabolize carbon-containing substances, and ends when carbon is incorporated into the cell or organism's metabolism.	tmpzr1t_l9r_go_relaxed.owl	heterotrophy|carbon utilization by utilization of organic compounds				Wikipedia:Heterotroph							GO:0015978		biological_process											owl:Class	
GO:0140241	biolink:NamedThing	translation at synapse	Translation that occurs at the synapse.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/synapse/issues/210				Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.		pg	2018-07-15T09:23:12Z					biological_process											owl:Class	
GO:0006412	biolink:NamedThing	translation	The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA or circRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA or circRNA. Translation ends with the release of a polypeptide chain from the ribosome.	tmpzr1t_l9r_go_relaxed.owl	protein biosynthesis|protein biosynthetic process|protein formation|protein anabolism|protein synthesis|protein translation				Wikipedia:Translation_(genetics)							GO:0006416|GO:0043037|GO:0006453		biological_process											owl:Class	
GO:0018624	biolink:NamedThing	toluene dioxygenase activity	Catalysis of the reaction: H(+) + NADH + O(2) + toluene = (1S,2R)-3-methylcyclohexa-3,5-diene-1,2-diol + NAD(+).	tmpzr1t_l9r_go_relaxed.owl	toluene,NADH:oxygen oxidoreductase (1,2-hydroxylating)|toluene 1,2-dioxygenase activity|toluene 2,3-dioxygenase activity				UM-BBD_enzymeID:e0155|MetaCyc:TOLUENE-DIOXYGENASE-RXN|KEGG_REACTION:R03559|EC:1.14.12.11|RHEA:16737									molecular_function											owl:Class	
GO:1905234	biolink:NamedThing	cellular response to codeine	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a codeine stimulus.	tmpzr1t_l9r_go_relaxed.owl								sl	2016-06-07T21:26:53Z					biological_process											owl:Class	
GO:0071317	biolink:NamedThing	cellular response to isoquinoline alkaloid	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an isoquinoline alkaloid stimulus. An isoquinoline alkaloid is any member of a group of compounds with the heterocyclic ring structure of benzo(c)pyridine which is a structure characteristic of the group of opium alkaloids.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-12-10T05:06:08Z					biological_process											owl:Class	
GO:0070134	biolink:NamedThing	positive regulation of mitochondrial translational initiation	Any process that activates or increases the frequency, rate or extent of the process preceding formation of the peptide bond between the first two amino acids of a protein in a mitochondrion.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of mitochondrial translation initiation													biological_process											owl:Class	
GO:0070131	biolink:NamedThing	positive regulation of mitochondrial translation	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA in a mitochondrion.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of mitochondrial protein biosynthesis|positive regulation of mitochondrial protein formation|positive regulation of mitochondrial protein anabolism|positive regulation of mitochondrial protein synthesis													biological_process											owl:Class	
GO:0032760	biolink:NamedThing	positive regulation of tumor necrosis factor production	Any process that activates or increases the frequency, rate or extent of tumor necrosis factor production.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of tumor necrosis factor biosynthesis|positive regulation of TNF-alpha production|positive regulation of tumor necrosis factor-alpha production|stimulation of tumor necrosis factor production|positive regulation of tumor necrosis factor formation|positive regulation of tumor necrosis factor biosynthetic process|activation of tumor necrosis factor production|positive regulation of TNF production|positive regulation of tumor necrosis factor secretion|up-regulation of tumor necrosis factor production|positive regulation of cachectin secretion|up regulation of tumor necrosis factor production|upregulation of tumor necrosis factor production|positive regulation of TNF secretion					Note that this term refers only to the specific, original 'tumor necrosis factor' protein (TNF) and not other members of the tumor necrosis factor superfamily (those with the gene symbol root 'TNFSF').		sl	2015-07-09T19:50:14Z			GO:0042535|GO:1904469		biological_process											owl:Class	
GO:1905281	biolink:NamedThing	positive regulation of retrograde transport, endosome to Golgi	Any process that activates or increases the frequency, rate or extent of retrograde transport, endosome to Golgi.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of retrograde (endosome to Golgi) transport|upregulation of retrograde (endosome to Golgi) transport|activation of retrograde transport, endosome to Golgi|up-regulation of retrograde transport, endosome to Golgi|activation of retrograde (endosome to Golgi) transport|upregulation of retrograde transport, endosome to Golgi|up-regulation of retrograde (endosome to Golgi) transport|up regulation of retrograde transport, endosome to Golgi|up regulation of retrograde (endosome to Golgi) transport							bf	2016-06-20T12:25:44Z					biological_process											owl:Class	
GO:1905279	biolink:NamedThing	regulation of retrograde transport, endosome to Golgi	Any process that modulates the frequency, rate or extent of retrograde transport, endosome to Golgi.	tmpzr1t_l9r_go_relaxed.owl	regulation of retrograde (endosome to Golgi) transport							bf	2016-06-20T12:25:29Z					biological_process											owl:Class	
GO:1903472	biolink:NamedThing	negative regulation of mitotic actomyosin contractile ring contraction	Any process that stops, prevents or reduces the frequency, rate or extent of mitotic actomyosin contractile ring contraction.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of contractile ring contraction involved in cell cycle cytokinesis involved in mitotic cell cycle|down-regulation of mitotic actomyosin contractile ring contraction|inhibition of mitotic actomyosin contractile ring contraction|downregulation of contractile ring contraction involved in cell cycle cytokinesis involved in mitotic cell cycle|downregulation of mitotic actomyosin contractile ring contraction|down-regulation of cytokinesis, actomyosin ring contraction involved in mitotic cell cycle|inhibition of contractile ring contraction involved in cell cycle cytokinesis involved in mitotic cell cycle|down regulation of cytokinesis, actomyosin ring contraction involved in mitotic cell cycle|down regulation of mitotic actomyosin contractile ring contraction|negative regulation of mitotic actomyosin contractile ring constriction|negative regulation of cytokinesis, actomyosin ring contraction involved in mitotic cell cycle|downregulation of cytokinesis, actomyosin ring contraction involved in mitotic cell cycle|negative regulation of contractile ring contraction involved in cell cycle cytokinesis involved in mitotic cell cycle|down regulation of contractile ring contraction involved in cell cycle cytokinesis involved in mitotic cell cycle|inhibition of cytokinesis, actomyosin ring contraction involved in mitotic cell cycle	https://github.com/geneontology/go-ontology/issues/21855						vw	2014-09-23T14:10:38Z					biological_process											owl:Class	
GO:0043127	biolink:NamedThing	negative regulation of 1-phosphatidylinositol 4-kinase activity	Any process that stops or reduces the activity of the enzyme 1-phosphatidylinositol 4-kinase.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of PI4K activity|downregulation of 1-phosphatidylinositol 4-kinase activity|inhibition of 1-phosphatidylinositol 4-kinase activity|down regulation of 1-phosphatidylinositol 4-kinase activity|down-regulation of 1-phosphatidylinositol 4-kinase activity													biological_process											owl:Class	
GO:0090219	biolink:NamedThing	negative regulation of lipid kinase activity	Any process that decreases the frequency, rate or extent of lipid kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a simple or complex lipid.	tmpzr1t_l9r_go_relaxed.owl								tb	2010-01-12T10:18:30Z					biological_process											owl:Class	
GO:0044028	biolink:NamedThing	DNA hypomethylation	An decrease in the epigenetic methylation of cytosine and adenosine residues in DNA.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0044030	biolink:NamedThing	regulation of DNA methylation	Any process that modulates the frequency, rate or extent of the covalent transfer of a methyl group to either N-6 of adenine or C-5 or N-4 of cytosine.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0043639	biolink:NamedThing	benzoate catabolic process	The chemical reactions and pathways resulting in the breakdown of benzoate, the anion of benzoic acid (benzenecarboxylic acid), a fungistatic compound widely used as a food preservative; it is conjugated to glycine in the liver and excreted as hippuric acid.	tmpzr1t_l9r_go_relaxed.owl	benzoate breakdown|benzoate catabolism|benzoate degradation													biological_process											owl:Class	
GO:0035098	biolink:NamedThing	ESC/E(Z) complex	A multimeric protein complex that can methylate lysine-27 and lysine-9 residues of histone H3. In Drosophila the core subunits of the complex include ESC, E(Z), CAF1 (NURF-55) and SU(Z)12. In mammals the core subunits of the complex include EED, EZH2, SUZ12 and RBBP4.	tmpzr1t_l9r_go_relaxed.owl	PRC2 complex|Extra Sex Combs/Enhancer of Zeste complex													cellular_component											owl:Class	
GO:0035097	biolink:NamedThing	histone methyltransferase complex	A multimeric complex that is able to catalyze the addition of methyl groups to histone proteins.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:1990565	biolink:NamedThing	HSP90-CDC37 chaperone complex	A protein kinase chaperone complex required for the proper folding, maturation and stabilization of target proteins (mostly signalling protein kinases, some steroid hormone receptors), usually during or immediately after completion of translation. The highly conserved, phosphorylated CDC37-Ser13 (vertebrates) or cdc37-Ser14 (yeast) is essential for complex assembly and target protein binding. CDC37-Ser13 (Ser14) is phosphorylated by Casein kinase II (CK2), which in turn is a target of CDC37 creating a positive feedback loop. Complex binding also prevents rapid ubiquitin-dependent proteosomal degradation of target proteins.	tmpzr1t_l9r_go_relaxed.owl						An example of this is HSP90AB1 in human (UniProt symbol P08238) in PMID:21855797 (inferred from direct assay).		bhm	2014-11-26T14:22:51Z					cellular_component											owl:Class	
GO:0101031	biolink:NamedThing	chaperone complex	A protein complex required for the non-covalent folding or unfolding, maturation, stabilization or assembly or disassembly of macromolecular structures. Usually active during or immediately after completion of translation. Many chaperone complexes contain heat shock proteins.	tmpzr1t_l9r_go_relaxed.owl						An example of this is HSP90AB1 in human (P08238) in PMID:21855797 (inferred from direct assay).								cellular_component											owl:Class	
GO:0030707	biolink:NamedThing	ovarian follicle cell development	The process that occurs during oogenesis involving the ovarian follicle cells, somatic cells which surround the germ cells of an ovary. An example of this is found in Drosophila melanogaster.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0019537	biolink:NamedThing	vibriobactin biosynthetic process	The chemical reactions and pathways resulting in the formation of vibriobactin, the major siderophore produced by Vibrio cholerae.	tmpzr1t_l9r_go_relaxed.owl	vibriobactin biosynthetic process, peptide modification|vibriobactin formation|vibriobactin biosynthetic process, peptide formation|vibriobactin anabolism|vibriobactin biosynthesis|vibriobactin synthesis											GO:0031195|GO:0031196		biological_process											owl:Class	
GO:1902519	biolink:NamedThing	response to docetaxel trihydrate	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a docetaxel trihydrate stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to docetaxel					Note that this term is in the subset of terms that should not be used for direct manual annotation of gene products. It was created to be used for cross-referencing by other ontologies. Direct annotations to this term may be amended during annotation QC.		dw	2013-12-02T09:44:04Z					biological_process											owl:Class	
GO:0007612	biolink:NamedThing	learning	Any process in an organism in which a relatively long-lasting adaptive behavioral change occurs as the result of experience.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Learning									biological_process											owl:Class	
GO:0007611	biolink:NamedThing	learning or memory	The acquisition and processing of information and/or the storage and retrieval of this information over time.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0046865	biolink:NamedThing	terpenoid transport	The directed movement of terpenoids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Terpenoids are a class of compounds characterized by an isoprenoid chemical structure and include derivatives with various functional groups.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0046864	biolink:NamedThing	isoprenoid transport	The directed movement of isoprenoids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Isoprenoids comprise a group of compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0140410	biolink:NamedThing	solute:bicarbonate symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: solute(out) + HCO3-(out) = solute(in) + HCO3-(in).	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/18345						pg	2020-01-07T16:58:49Z					molecular_function											owl:Class	
GO:0015106	biolink:NamedThing	bicarbonate transmembrane transporter activity	Enables the transfer of bicarbonate from one side of a membrane to the other. Bicarbonate is the hydrogencarbonate ion, HCO3-.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-2752067|RHEA:28695									molecular_function											owl:Class	
GO:0045813	biolink:NamedThing	positive regulation of Wnt signaling pathway, calcium modulating pathway	Any process that activates or increases the frequency, rate or extent of the series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors leads to an increase in intracellular calcium and activation of protein kinase C (PKC).	tmpzr1t_l9r_go_relaxed.owl	stimulation of frizzled-2 signaling pathway|activation of frizzled-2 signaling pathway|positive regulation of Wnt receptor signaling pathway, calcium modulating pathway|positive regulation of Wnt-activated signaling pathway, calcium modulating pathway|upregulation of frizzled-2 signaling pathway|up regulation of frizzled-2 signaling pathway|positive regulation of frizzled-2 signalling pathway|positive regulation of frizzled-2 signaling pathway|up-regulation of frizzled-2 signaling pathway													biological_process											owl:Class	
GO:0102623	biolink:NamedThing	scutellarein 7-methyl ether 6-O-methyltransferase activity	Catalysis of the reaction: scutellarein 7-methyl ether + S-adenosyl-L-methionine  <=> cirsimaritin + S-adenosyl-L-homocysteine  + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-15528									molecular_function											owl:Class	
GO:1904024	biolink:NamedThing	negative regulation of glucose catabolic process to lactate via pyruvate	Any process that stops, prevents or reduces the frequency, rate or extent of glucose catabolic process to lactate via pyruvate.	tmpzr1t_l9r_go_relaxed.owl	inhibition of homolactic fermentation|down-regulation of homofermentative pathway|downregulation of homolactate fermentation|negative regulation of homofermentation|down-regulation of homofermentation|negative regulation of glucose fermentation to lactate via pyruvate|down regulation of homolactate fermentation|down regulation of homofermentative pathway|downregulation of glucose fermentation to lactate via pyruvate|downregulation of homofermentation|negative regulation of homofermentative pathway|down regulation of homolactic fermentation|down-regulation of glucose fermentation to lactate via pyruvate|inhibition of homolactate fermentation|inhibition of homofermentative lactate fermentation|down-regulation of homolactate fermentation|inhibition of glucose fermentation to lactate via pyruvate|downregulation of homolactic fermentation|inhibition of homofermentative pathway|down-regulation of glucose catabolic process to lactate via pyruvate|negative regulation of homofermentative lactate fermentation|downregulation of homofermentative pathway|down-regulation of homofermentative lactate fermentation|down regulation of glucose catabolic process to lactate via pyruvate|down regulation of homofermentative lactate fermentation|negative regulation of homolactate fermentation|down-regulation of homolactic fermentation|inhibition of homofermentation|inhibition of glucose catabolic process to lactate via pyruvate|down regulation of glucose fermentation to lactate via pyruvate|downregulation of glucose catabolic process to lactate via pyruvate|negative regulation of homolactic fermentation|down regulation of homofermentation|downregulation of homofermentative lactate fermentation							dph	2015-03-11T16:57:38Z					biological_process											owl:Class	
GO:1900555	biolink:NamedThing	emericellamide metabolic process	The chemical reactions and pathways involving emericellamide.	tmpzr1t_l9r_go_relaxed.owl	emericellamide metabolism							di	2012-05-15T01:32:19Z					biological_process											owl:Class	
GO:0018074	biolink:NamedThing	peptidyl-histidine bromination	The bromination of peptidyl-histidine to form peptidyl-L-bromohistidine; the position of the bromine substitution is unknown.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0173									biological_process											owl:Class	
GO:0018073	biolink:NamedThing	protein bromination	The addition of one or more bromine atoms to an amino acid residue in a protein.	tmpzr1t_l9r_go_relaxed.owl	protein amino acid bromination													biological_process											owl:Class	
GO:1904958	biolink:NamedThing	positive regulation of midbrain dopaminergic neuron differentiation	Any process that activates or increases the frequency, rate or extent of midbrain dopaminergic neuron differentiation.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of midbrain dopaminergic neuron production|upregulation of DA neurogenesis from midbrain floor plate|up-regulation of midbrain dopaminergic neuron differentiation|upregulation of midbrain dopaminergic neuron production|up regulation of midbrain DA neurogenesis|up-regulation of DA neurogenesis from midbrain floor plate|upregulation of mDA neuron differentiation|upregulation of midbrain DA neurogenesis|activation of midbrain dopaminergic neuron production|up regulation of midbrain dopaminergic neuron differentiation|activation of mDA neuron differentiation|up regulation of mDA neuron differentiation|positive regulation of midbrain dopaminergic neuron production|up regulation of midbrain dopaminergic neuron production|up regulation of DA neurogenesis from midbrain floor plate|activation of midbrain DA neurogenesis|positive regulation of mDA neuron differentiation|activation of DA neurogenesis from midbrain floor plate|upregulation of midbrain dopaminergic neuron differentiation|up-regulation of midbrain DA neurogenesis|positive regulation of midbrain DA neurogenesis|positive regulation of DA neurogenesis from midbrain floor plate|up-regulation of mDA neuron differentiation|activation of midbrain dopaminergic neuron differentiation							bf	2016-02-09T12:00:36Z					biological_process											owl:Class	
GO:1904956	biolink:NamedThing	regulation of midbrain dopaminergic neuron differentiation	Any process that modulates the frequency, rate or extent of midbrain dopaminergic neuron differentiation.	tmpzr1t_l9r_go_relaxed.owl	regulation of mDA neuron differentiation|regulation of midbrain DA neurogenesis|regulation of DA neurogenesis from midbrain floor plate|regulation of midbrain dopaminergic neuron production							bf	2016-02-09T12:00:21Z					biological_process											owl:Class	
GO:0039525	biolink:NamedThing	modulation by virus of host chromatin organization	Any process in which a virus effects a change in the organization of chromatin in the host.	tmpzr1t_l9r_go_relaxed.owl	modulation of host chromatin by virus|modulation by virus of host chromatin organisation|regulation by virus of host chromatin organization|modulation of host chromatin structure by virus							bf	2011-06-22T05:11:13Z					biological_process											owl:Class	
GO:1904971	biolink:NamedThing	regulation of viral translation	Any process that modulates the frequency, rate or extent of viral translation.	tmpzr1t_l9r_go_relaxed.owl	regulation of viral protein biosynthetic process|regulation of viral protein formation|regulation of viral protein anabolism|regulation of viral protein biosynthesis|regulation of viral protein synthesis							bhm	2016-02-17T15:52:59Z					biological_process											owl:Class	
GO:0050792	biolink:NamedThing	regulation of viral process	Any process that modulates the rate or extent of the viral life cycle, the set of processes by which a virus reproduces and spreads among hosts.	tmpzr1t_l9r_go_relaxed.owl	regulation of viral reproduction													biological_process											owl:Class	
GO:0008807	biolink:NamedThing	carboxyvinyl-carboxyphosphonate phosphorylmutase activity	Catalysis of the reaction: 1-carboxyvinyl carboxyphosphonate = 3-(hydrohydroxyphosphoryl)pyruvate + CO2.	tmpzr1t_l9r_go_relaxed.owl	1-carboxyvinyl carboxyphosphonate phosphorylmutase (decarboxylating)|carboxyphosphonoenolpyruvate phosphonomutase activity|CPEP phosphonomutase activity				RHEA:14045|EC:2.7.8.23|MetaCyc:2.7.8.23-RXN									molecular_function											owl:Class	
GO:0090183	biolink:NamedThing	regulation of kidney development	Any process that modulates the rate, frequency or extent of kidney development. Kidney development is the process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine.	tmpzr1t_l9r_go_relaxed.owl	regulation of nephrogenesis							tb	2009-12-18T10:50:56Z					biological_process											owl:Class	
GO:0032684	biolink:NamedThing	negative regulation of fractalkine production	Any process that stops, prevents, or reduces the frequency, rate, or extent of fractalkine production.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of fractalkine production|negative regulation of fractalkine biosynthetic process|negative regulation of CX3CL1 production|down regulation of fractalkine production|downregulation of fractalkine production|inhibition of fractalkine production|negative regulation of CX3CL1 biosynthesis	https://github.com/geneontology/go-ontology/issues/19254										GO:0050753		biological_process											owl:Class	
GO:0032682	biolink:NamedThing	negative regulation of chemokine production	Any process that stops, prevents, or reduces the frequency, rate, or extent of chemokine production.	tmpzr1t_l9r_go_relaxed.owl	downregulation of chemokine production|negative regulation of chemokine biosynthetic process|negative regulation of chemokine secretion|down-regulation of chemokine production|down regulation of chemokine production|inhibition of chemokine production								2009-12-18T11:28:00Z			GO:0090198|GO:0045079		biological_process											owl:Class	
GO:0070560	biolink:NamedThing	protein secretion by platelet	The regulated release of proteins by a platelet or group of platelets.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-04-09T02:38:05Z					biological_process											owl:Class	
GO:0009306	biolink:NamedThing	protein secretion	The controlled release of proteins from a cell.	tmpzr1t_l9r_go_relaxed.owl	glycoprotein secretion|protein secretion during cell fate commitment|protein secretion resulting in cell fate commitment											GO:0045731|GO:0045166		biological_process											owl:Class	
GO:0150033	biolink:NamedThing	negative regulation of protein localization to lysosome	Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to lysosome.	tmpzr1t_l9r_go_relaxed.owl								bc	2018-02-06T17:14:16Z					biological_process											owl:Class	
GO:0045007	biolink:NamedThing	depurination	The disruption of the bond between the sugar in the backbone and the A or G base, causing the base to be removed and leaving a depurinated sugar.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Depurination									biological_process											owl:Class	
GO:0019690	biolink:NamedThing	pyrimidine deoxyribonucleoside interconversion	The chemical reactions and pathways by which a pyrimidine deoxyribonucleoside is synthesized from another deoxyribopyrimidine nucleoside.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1904588	biolink:NamedThing	cellular response to glycoprotein	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glycoprotein stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to glycoproteins							sl	2015-08-20T16:46:30Z					biological_process											owl:Class	
GO:1904587	biolink:NamedThing	response to glycoprotein	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glycoprotein stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to glycoproteins							sl	2015-08-20T16:46:24Z					biological_process											owl:Class	
GO:0005981	biolink:NamedThing	regulation of glycogen catabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glycogen.	tmpzr1t_l9r_go_relaxed.owl	regulation of glycogen breakdown|regulation of glycogen catabolism|regulation of glycogen degradation|regulation of glycogenolysis													biological_process											owl:Class	
GO:0032060	biolink:NamedThing	bleb assembly	The assembly of a bleb, a cell extension caused by localized decoupling of the cytoskeleton from the plasma membrane and characterized by rapid formation, rounded shape, and scarcity of organelles within the protrusion. Plasma membrane blebbing occurs during apoptosis and other cellular processes, including cell locomotion, cell division, and as a result of physical or chemical stresses.	tmpzr1t_l9r_go_relaxed.owl	cell blebbing|membrane blebbing|plasma membrane bleb assembly|blebbing|plasma membrane blebbing													biological_process											owl:Class	
GO:0038054	biolink:NamedThing	G protein-coupled estrogen receptor activity	Combining with estrogen and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.	tmpzr1t_l9r_go_relaxed.owl	G-protein coupled estrogen receptor activity							bf	2011-11-29T04:29:42Z					molecular_function											owl:Class	
GO:0030284	biolink:NamedThing	estrogen receptor activity	Combining with estrogen and transmitting the signal within the cell to trigger a change in cell activity or function.	tmpzr1t_l9r_go_relaxed.owl						For estrogen receptors that function within the nucleus to modulate transcription, consider instead annotating to the child terms 'estrogen-activated sequence-specific DNA binding RNA polymerase II transcription factor activity ; GO:0038052' or 'estrogen-activated RNA polymerase II transcription factor binding transcription factor activity ; GO:0038053'.								molecular_function											owl:Class	
GO:1901674	biolink:NamedThing	regulation of histone H3-K27 acetylation	Any process that modulates the frequency, rate or extent of histone H3-K27 acetylation.	tmpzr1t_l9r_go_relaxed.owl	regulation of histone H3 acetylation at K27|regulation of histone H3K27 acetylation							vk	2012-11-22T12:06:31Z					biological_process											owl:Class	
GO:0002571	biolink:NamedThing	somatic diversification of T cell receptor genes by N region addition	The addition of variable numbers of random nucleotides by terminal deoxytransferase in the N regions of T cell receptor genes. N regions are found at the V-D, D-D, V-J, and D-J recombinational junctions, depending on the T cell receptor gene.	tmpzr1t_l9r_go_relaxed.owl	somatic diversification of TCR genes by N region addition													biological_process											owl:Class	
GO:0002568	biolink:NamedThing	somatic diversification of T cell receptor genes	The somatic process that results in the generation of sequence diversity of T cell receptor genes.	tmpzr1t_l9r_go_relaxed.owl	somatic diversification of TCR genes													biological_process											owl:Class	
GO:0070842	biolink:NamedThing	aggresome assembly	The aggregation, arrangement and bonding together of a set of components to form an aggresome; requires the microtubule cytoskeleton and dynein.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-07-31T01:30:25Z					biological_process											owl:Class	
GO:0070841	biolink:NamedThing	inclusion body assembly	The aggregation, arrangement and bonding together of a set of components to form an inclusion body.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-07-31T01:28:14Z					biological_process											owl:Class	
GO:0047576	biolink:NamedThing	4-chlorobenzoate dehalogenase activity	Catalysis of the reaction: 4-chlorobenzoate + H(2)O = 4-hydroxybenzoate + chloride + H(+).	tmpzr1t_l9r_go_relaxed.owl	4-chlorobenzoate chlorohydrolase activity|halobenzoate dehalogenase activity				KEGG_REACTION:R01307|EC:3.8.1.6|MetaCyc:4-CHLOROBENZOATE-DEHALOGENASE-RXN|RHEA:23440									molecular_function											owl:Class	
GO:0071647	biolink:NamedThing	negative regulation of macrophage inflammatory protein-1 gamma production	Any process that stops, prevents, or reduces the frequency, rate, or extent of production of macrophage inflammatory protein-1 gamma.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of MIP-1g production|negative regulation of CCL9 production|negative regulation of chemokine (C-C motif) ligand 9 production							mah	2010-02-12T10:40:19Z					biological_process											owl:Class	
GO:0002207	biolink:NamedThing	gene conversion of immunoglobulin genes involved in immune response	The somatic process in which immunoglobulin genes are diversified through the mechanism of gene conversion following the induction of and contributing to an immune response.	tmpzr1t_l9r_go_relaxed.owl	gene conversion of immunoglobulin genes during immune response|gene conversion of antibody genes during immune response													biological_process											owl:Class	
GO:0002206	biolink:NamedThing	gene conversion of immunoglobulin genes	The somatic process in which immunoglobulin genes are diversified through the mechanism of gene conversion.	tmpzr1t_l9r_go_relaxed.owl	gene conversion of antibody genes													biological_process											owl:Class	
GO:0018921	biolink:NamedThing	3-hydroxybenzyl alcohol metabolic process	The chemical reactions and pathways involving 3-hydroxybenzyl alcohol, an aromatic compound which is an intermediate in several metabolic pathways, including the biosynthesis of patulin, a toxin and antiviral agent produced by some moulds such as Penicillium patulinum.	tmpzr1t_l9r_go_relaxed.owl	3-hydroxybenzyl alcohol metabolism				UM-BBD_pathwayID:mcr									biological_process											owl:Class	
GO:0045659	biolink:NamedThing	negative regulation of neutrophil differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of neutrophil differentiation.	tmpzr1t_l9r_go_relaxed.owl	inhibition of neutrophil differentiation|down regulation of neutrophil differentiation|down-regulation of neutrophil differentiation|downregulation of neutrophil differentiation													biological_process											owl:Class	
GO:0030853	biolink:NamedThing	negative regulation of granulocyte differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of granulocyte differentiation.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of granulocyte differentiation|downregulation of granulocyte differentiation|inhibition of granulocyte differentiation|down regulation of granulocyte differentiation													biological_process											owl:Class	
GO:0003851	biolink:NamedThing	2-hydroxyacylsphingosine 1-beta-galactosyltransferase activity	Catalysis of the reaction: UDP-galactose + 2-(2-hydroxyacyl)sphingosine = UDP + 1-(beta-D-galactosyl)-2-(2-hydroxyacyl)sphingosine.	tmpzr1t_l9r_go_relaxed.owl	cerebroside synthase activity|UDP-galactose:2-(2-hydroxyacyl)sphingosine 1-beta-D-galactosyl-transferase activity|UDPgalactose:2-2-hydroxyacylsphingosine galactosyltransferase activity|uridine diphosphogalactose-2-hydroxyacylsphingosine galactosyltransferase activity|UDPgalactose:ceramide galactosyltransferase activity|UDPgalactose-2-hydroxyacylsphingosine galactosyltransferase activity|UDPgalactose:2-(2-hydroxyacyl)sphingosine 1-beta-D-galactosyl-transferase activity|UDP-galactose-ceramide galactosyltransferase activity				EC:2.4.1.47|MetaCyc:2.4.1.45-RXN|RHEA:10856									molecular_function											owl:Class	
GO:1901108	biolink:NamedThing	granaticin catabolic process	The chemical reactions and pathways resulting in the breakdown of granaticin.	tmpzr1t_l9r_go_relaxed.owl	granaticin breakdown|granaticin catabolism|granaticin degradation							yaf	2012-07-11T02:51:33Z					biological_process											owl:Class	
GO:0009754	biolink:NamedThing	detection of jasmonic acid stimulus	The series of events in which a jasmonic acid stimulus is received by a cell and converted into a molecular signal. Series of events required for a jasmonic acid stimulus to be detected and converted to a signal molecule.	tmpzr1t_l9r_go_relaxed.owl	perception of jasmonic acid stimulus													biological_process											owl:Class	
GO:0032331	biolink:NamedThing	negative regulation of chondrocyte differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of chondrocyte differentiation.	tmpzr1t_l9r_go_relaxed.owl	down regulation of chondrocyte differentiation|inhibition of chondrocyte differentiation|downregulation of chondrocyte differentiation|down-regulation of chondrocyte differentiation													biological_process											owl:Class	
GO:1900175	biolink:NamedThing	regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry	Any process that modulates the frequency, rate or extent of a nodal signaling pathway, where the nodal signaling pathway is involved in determination of left/right asymmetry in the lateral mesoderm.	tmpzr1t_l9r_go_relaxed.owl	regulation of nodal signalling pathway involved in determination of lateral mesoderm left/right asymmetry							bf	2012-03-09T10:39:10Z					biological_process											owl:Class	
GO:1900336	biolink:NamedThing	regulation of methane biosynthetic process from carbon monoxide	Any process that modulates the frequency, rate or extent of methane biosynthetic process from carbon monoxide.	tmpzr1t_l9r_go_relaxed.owl								tt	2012-04-06T02:03:15Z					biological_process											owl:Class	
GO:0043457	biolink:NamedThing	regulation of cellular respiration	Any process that modulates the frequency, rate or extent of cellular respiration, the enzymatic release of energy from organic compounds.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:2001121	biolink:NamedThing	coenzyme gamma-F420-2 biosynthetic process	The chemical reactions and pathways resulting in the formation of a coenzyme gamma-F420-2.	tmpzr1t_l9r_go_relaxed.owl	coenzyme gamma-F420-2 biosynthesis							jl	2011-10-11T02:38:14Z					biological_process											owl:Class	
GO:1901137	biolink:NamedThing	carbohydrate derivative biosynthetic process	The chemical reactions and pathways resulting in the formation of carbohydrate derivative.	tmpzr1t_l9r_go_relaxed.owl	carbohydrate derivative synthesis|carbohydrate derivative anabolism|carbohydrate derivative biosynthesis|carbohydrate derivative formation							bf	2012-07-12T04:05:39Z					biological_process											owl:Class	
GO:0075010	biolink:NamedThing	regulation of germ tube formation	Any process that modulates the frequency, rate or extent of germ tube formation on or near host. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl						Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products from the symbiont involved in this process.								biological_process											owl:Class	
GO:0009637	biolink:NamedThing	response to blue light	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a blue light stimulus. Blue light is electromagnetic radiation with a wavelength of between 440 and 500nm.	tmpzr1t_l9r_go_relaxed.owl	response to blue light stimulus													biological_process											owl:Class	
GO:0010893	biolink:NamedThing	positive regulation of steroid biosynthetic process	Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0046889	biolink:NamedThing	positive regulation of lipid biosynthetic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of lipids.	tmpzr1t_l9r_go_relaxed.owl	stimulation of lipid biosynthetic process|positive regulation of lipid biosynthesis|up-regulation of lipid biosynthetic process|activation of lipid biosynthetic process|up regulation of lipid biosynthetic process|upregulation of lipid biosynthetic process|positive regulation of lipid formation|positive regulation of lipid synthesis|positive regulation of lipogenesis|positive regulation of lipid anabolism													biological_process											owl:Class	
GO:0034686	biolink:NamedThing	integrin alphav-beta8 complex	An integrin complex that comprises one alphav subunit and one beta8 subunit.	tmpzr1t_l9r_go_relaxed.owl	alphav-beta8 integrin complex|ITGAV-ITGB8 complex													cellular_component											owl:Class	
GO:0001851	biolink:NamedThing	complement component C3b binding	Binding to a C3b product of the complement cascade.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0001846	biolink:NamedThing	opsonin binding	Binding to an opsonin, such as a complement component or antibody, deposited on the surface of a bacteria, virus, immune complex, or other particulate material.	tmpzr1t_l9r_go_relaxed.owl						Note that an opsonin is a blood serum protein or fragment which when deposited on the surface of a bacteria, virus, immune complex, or other particulate material acts a signal for phagocytosis to cells bearing the appropriate receptors. Not all complement components or fragments and not all antibodies have opsonic properties.								molecular_function											owl:Class	
GO:0034395	biolink:NamedThing	regulation of transcription from RNA polymerase II promoter in response to iron	Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter in response to an iron stimulus.	tmpzr1t_l9r_go_relaxed.owl	regulation of specific transcription from RNA polymerase II promoter in response to iron													biological_process											owl:Class	
GO:0006357	biolink:NamedThing	regulation of transcription by RNA polymerase II	Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II.	tmpzr1t_l9r_go_relaxed.owl	global transcription regulation from Pol II promoter|regulation of transcription from RNA polymerase II promoter|regulation of global transcription from Pol II promoter|regulation of transcription from Pol II promoter|regulation of gene-specific transcription from RNA polymerase II promoter|regulation of transcription from RNA polymerase II promoter, global											GO:0010551|GO:0006358		biological_process											owl:Class	
GO:0048035	biolink:NamedThing	heme O catabolic process	The chemical reactions and pathways resulting in the breakdown of heme O, a derivative of heme containing a 17-carbon hydroxyethylfarnesyl side chain at position 8 of the tetrapyrrole macrocycle.	tmpzr1t_l9r_go_relaxed.owl	heme O breakdown|haem O catabolism|heme O catabolism|haem O catabolic process|heme O degradation													biological_process											owl:Class	
GO:0035042	biolink:NamedThing	fertilization, exchange of chromosomal proteins	Replacement of sperm-specific chromosomal proteins with somatic histones, to allow the paternal genome to acquire a nucleosomal chromatin organization compatible with nuclear activity.	tmpzr1t_l9r_go_relaxed.owl	sperm-specific histone exchange|sperm-specific histone replacement													biological_process											owl:Class	
GO:0032879	biolink:NamedThing	regulation of localization	Any process that modulates the frequency, rate or extent of any process in which a cell, a substance, or a cellular entity is transported to, or maintained in, a specific location.	tmpzr1t_l9r_go_relaxed.owl	regulation of localisation													biological_process											owl:Class	
GO:0045953	biolink:NamedThing	negative regulation of natural killer cell mediated cytotoxicity	Any process that stops, prevents, or reduces the rate of natural killer mediated cytotoxicity.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of NK cell mediated cytotoxicity|negative regulation of NK cell mediated cell killing|down regulation of natural killer cell mediated cytotoxicity|negative regulation of natural killer cell mediated cytolysis|negative regulation of NK cell mediated cell death|downregulation of natural killer cell mediated cytotoxicity|negative regulation of natural killer cell mediated cell death|negative regulation of natural killer cell mediated cell killing|negative regulation of NK cell mediated cytolysis|down-regulation of natural killer cell mediated cytotoxicity|inhibition of natural killer cell mediated cytotoxicity													biological_process											owl:Class	
GO:0042269	biolink:NamedThing	regulation of natural killer cell mediated cytotoxicity	Any process that modulates the frequency, rate, or extent of natural killer cell mediated cytotoxicity.	tmpzr1t_l9r_go_relaxed.owl	regulation of NK cell mediated cytolysis|regulation of natural killer cell mediated cell killing|regulation of natural killer cell mediated cell death|regulation of natural killer cell mediated cytolysis|regulation of NK cell mediated cytotoxicity|regulation of NK cell mediated cell killing|regulation of NK cell mediated cell death|regulation of natural killer-cell mediated cytolysis													biological_process											owl:Class	
GO:0032449	biolink:NamedThing	CBM complex	A protein complex comprising Bcl10, MALT1 and a CARD domain-containing protein (CARD9, CARD10 or CARD11); plays a role in signal transduction during NF-kappaB activation.	tmpzr1t_l9r_go_relaxed.owl	CARMA1-BCL10-Malt1 complex	https://github.com/geneontology/go-ontology/issues/21010												cellular_component											owl:Class	
GO:0016445	biolink:NamedThing	somatic diversification of immunoglobulins	The somatic process that results in the generation of sequence diversity of immunoglobulins.	tmpzr1t_l9r_go_relaxed.owl	somatic diversification of antibodies													biological_process											owl:Class	
GO:0009976	biolink:NamedThing	tocopherol cyclase activity	Catalysis of the reaction: alkene group + alcohol group on same molecule = cyclic ether. Substrates are 2-methyl-6-phytyl-1,4- hydroquinone (forms delta-tocopherol) and 2,3-dimethyl-5-phytyl-1,4-hydroquinone (forms gamma-tocopherol).	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0099032	biolink:NamedThing	anchored component of postsynaptic early endosome membrane	The component of the postsynaptic early endosome membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0098950	biolink:NamedThing	intrinsic component of postsynaptic early endosome membrane	The component of the postsynaptic early endosome membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.	tmpzr1t_l9r_go_relaxed.owl	intrinsic to postsynaptic early endosome membrane													cellular_component											owl:Class	
GO:0086028	biolink:NamedThing	bundle of His cell to Purkinje myocyte signaling	Any process that mediates the transfer of information from a bundle of His cardiomyocyte to a Purkinje myocyte.	tmpzr1t_l9r_go_relaxed.owl	bundle of His cardiac muscle cell to Purkinje myocyte signaling|bundle of His cardiac muscle cell to Purkinje myocyte signalling							tb	2011-11-11T02:02:14Z					biological_process											owl:Class	
GO:0086069	biolink:NamedThing	bundle of His cell to Purkinje myocyte communication	The process that mediates interactions between a bundle of His cell and its surroundings that contributes to the process of the bundle of His cell communicating with a Purkinje myocyte in cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.	tmpzr1t_l9r_go_relaxed.owl	atrioventricular junction myocyte to bundle branch myocyte|bundle of His cardiac muscle cell to Purkinje myocyte communication|ventricular conduction system cell to cell communication|bundle branch myocyte to Purkinje myocyte communication|bundle of His myocyte to atrioventricular junction myocyte	https://github.com/geneontology/go-ontology/issues/20731						dph	2011-11-22T09:18:49Z					biological_process											owl:Class	
GO:0098702	biolink:NamedThing	adenine import across plasma membrane	The directed movement of adenine from outside of a cell, across the plasma membrane and into the cytosol.	tmpzr1t_l9r_go_relaxed.owl	adenine import into cell							dph	2012-12-06T14:51:42Z			GO:0061488		biological_process											owl:Class	
GO:0015853	biolink:NamedThing	adenine transport	The directed movement of adenine, 6-aminopurine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	adenine transmembrane transport													biological_process											owl:Class	
GO:0071923	biolink:NamedThing	negative regulation of cohesin loading	Any process that stops, prevents, or reduces the frequency, rate or extent of a process in which a cohesin complex is transported to, or maintained at, a part of a chromosome that is organized into chromatin.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of cohesin localisation to chromatin|negative regulation of cohesin localization to chromatin|negative regulation of cohesin association with chromatin							mah	2010-09-28T11:17:50Z					biological_process											owl:Class	
GO:0071668	biolink:NamedThing	plant-type cell wall assembly	The aggregation, arrangement and bonding together of a set of components to form a cellulose- and pectin-containing cell wall.	tmpzr1t_l9r_go_relaxed.owl	plant cell wall assembly							mah	2010-02-15T02:19:39Z					biological_process											owl:Class	
GO:0009664	biolink:NamedThing	plant-type cell wall organization	A process that results in the assembly and arrangement of constituent parts of the cellulose and pectin-containing cell wall, or in the disassembly of the cellulose and pectin-containing cell wall. This process is carried out at the cellular level. An example of this process is found in Arabidopsis thaliana.	tmpzr1t_l9r_go_relaxed.owl	plant-type cell wall organisation|cell wall organization and biogenesis|plant-type cell wall organization and biogenesis|cellulose and pectin-containing cell wall organization and biogenesis													biological_process											owl:Class	
GO:0030593	biolink:NamedThing	neutrophil chemotaxis	The directed movement of a neutrophil cell, the most numerous polymorphonuclear leukocyte found in the blood, in response to an external stimulus, usually an infection or wounding.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0071621	biolink:NamedThing	granulocyte chemotaxis	The movement of a granulocyte in response to an external stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-02-09T04:08:17Z					biological_process											owl:Class	
GO:0140298	biolink:NamedThing	endocytic iron import into cell	Uptake of iron into a cell via binding to an extracellular receptor, which is internalized by endocytosis.	tmpzr1t_l9r_go_relaxed.owl	iron import into cell by endocytosis							pg	2018-12-10T10:31:31Z					biological_process											owl:Class	
GO:0006898	biolink:NamedThing	receptor-mediated endocytosis	An endocytosis process in which cell surface receptors ensure specificity of transport. A specific receptor on the cell surface binds tightly to the extracellular macromolecule (the ligand) that it recognizes; the plasma-membrane region containing the receptor-ligand complex then undergoes endocytosis, forming a transport vesicle containing the receptor-ligand complex and excluding most other plasma-membrane proteins. Receptor-mediated endocytosis generally occurs via clathrin-coated pits and vesicles.	tmpzr1t_l9r_go_relaxed.owl	receptor mediated endocytosis				Wikipedia:Receptor-mediated_endocytosis									biological_process											owl:Class	
GO:1903581	biolink:NamedThing	regulation of basophil degranulation	Any process that modulates the frequency, rate or extent of basophil degranulation.	tmpzr1t_l9r_go_relaxed.owl								sl	2014-10-31T17:37:24Z					biological_process											owl:Class	
GO:0032965	biolink:NamedThing	regulation of collagen biosynthetic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals.	tmpzr1t_l9r_go_relaxed.owl	regulation of collagen synthesis|regulation of collagen biosynthesis|regulation of collagen anabolism|regulation of collagen formation													biological_process											owl:Class	
GO:2000016	biolink:NamedThing	negative regulation of determination of dorsal identity	Any process that stops, prevents, or reduces the frequency, rate or extent of determination of dorsal identity.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of determination of adaxial identity							jl	2010-07-15T03:27:55Z					biological_process											owl:Class	
GO:0051322	biolink:NamedThing	anaphase	The cell cycle phase, following metaphase, during which the chromosomes separate and migrate towards the poles of the spindle.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Anaphase	Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).								biological_process											owl:Class	
GO:0022403	biolink:NamedThing	cell cycle phase	One of the distinct periods or stages into which the cell cycle is divided. Each phase is characterized by the occurrence of specific biochemical and morphological events.	tmpzr1t_l9r_go_relaxed.owl						Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).								biological_process											owl:Class	
GO:0046208	biolink:NamedThing	spermine catabolic process	The chemical reactions and pathways resulting in the breakdown of spermine, a polybasic amine found in human sperm, in ribosomes and in some viruses and involved in nucleic acid packaging.	tmpzr1t_l9r_go_relaxed.owl	spermine breakdown|spermine degradation|spermine catabolism													biological_process											owl:Class	
GO:0008215	biolink:NamedThing	spermine metabolic process	The chemical reactions and pathways involving spermine, a polybasic amine found in human sperm, in ribosomes and in some viruses, which is involved in nucleic acid packaging. Synthesis is regulated by ornithine decarboxylase which plays a key role in control of DNA replication.	tmpzr1t_l9r_go_relaxed.owl	spermine metabolism													biological_process											owl:Class	
GO:0044834	biolink:NamedThing	retroviral intasome	A tetramer of retroviral integrase subunits tightly associated with a pair of viral DNA ends. Functions to insert viral DNA into a host cell chromosome.	tmpzr1t_l9r_go_relaxed.owl								jl	2014-02-06T14:33:39Z					cellular_component											owl:Class	
GO:0032993	biolink:NamedThing	protein-DNA complex	A macromolecular complex containing both protein and DNA molecules.	tmpzr1t_l9r_go_relaxed.owl	DNA-protein complex					Note that this term is intended to classify complexes that have DNA as one of the members of the complex, that is, the complex does not exist if DNA is not present. Protein complexes that interact with DNA e.g. transcription factor complexes should not be classified here.								cellular_component											owl:Class	
GO:0001918	biolink:NamedThing	farnesylated protein binding	Binding to a farnesylated protein.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0006449	biolink:NamedThing	regulation of translational termination	Any process that modulates the frequency, rate or extent of translational termination.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0043923	biolink:NamedThing	positive regulation by host of viral transcription	Any process in which a host organism activates or increases the frequency, rate or extent of viral transcription, the synthesis of either RNA on a template of DNA or DNA on a template of RNA.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of viral transcription by host													biological_process											owl:Class	
GO:0000329	biolink:NamedThing	fungal-type vacuole membrane	The lipid bilayer surrounding a vacuole, the shape of which correlates with cell cycle phase. The membrane separates its contents from the cytoplasm of the cell. An example of this structure is found in Saccharomyces cerevisiae.	tmpzr1t_l9r_go_relaxed.owl	fungal-type vacuolar membrane|membrane of vacuole with cell cycle-correlated morphology													cellular_component											owl:Class	
GO:0098852	biolink:NamedThing	lytic vacuole membrane	The lipid bilayer surrounding a lytic vacuole and separating its contents from the cytoplasm of the cell.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:2000736	biolink:NamedThing	regulation of stem cell differentiation	Any process that modulates the frequency, rate or extent of stem cell differentiation.	tmpzr1t_l9r_go_relaxed.owl								yaf	2011-06-14T02:05:16Z					biological_process											owl:Class	
GO:2000062	biolink:NamedThing	negative regulation of ureter smooth muscle cell differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of ureter smooth muscle cell differentiation.	tmpzr1t_l9r_go_relaxed.owl								jl	2010-08-20T01:44:23Z					biological_process											owl:Class	
GO:0051151	biolink:NamedThing	negative regulation of smooth muscle cell differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of smooth muscle cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of smooth muscle cell differentiation|down regulation of smooth muscle cell differentiation|downregulation of smooth muscle cell differentiation|inhibition of smooth muscle cell differentiation													biological_process											owl:Class	
GO:0009513	biolink:NamedThing	etioplast	A plastid arrested in the development of chloroplasts from proplastids due to absence of light or low light conditions.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Etioplast									cellular_component											owl:Class	
GO:0009536	biolink:NamedThing	plastid	Any member of a family of organelles found in the cytoplasm of plants and some protists, which are membrane-bounded and contain DNA. Plant plastids develop from a common type, the proplastid.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Plastid									cellular_component											owl:Class	
GO:0050197	biolink:NamedThing	phytanate-CoA ligase activity	Catalysis of the reaction: ATP + CoA + phytanate = AMP + diphosphate + H(+) + phytanoyl-CoA.	tmpzr1t_l9r_go_relaxed.owl	phytanate:CoA ligase (AMP-forming)|phytanoyl-CoA ligase activity				Reactome:R-HSA-389622|MetaCyc:PHYTANATE--COA-LIGASE-RXN|RHEA:21380|KEGG_REACTION:R03631|EC:6.2.1.24									molecular_function											owl:Class	
GO:0007344	biolink:NamedThing	pronuclear fusion	The merging of two pronuclei in a fertilized egg to fuse and produce a single zygotic genome.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0000741	biolink:NamedThing	karyogamy	The creation of a single nucleus from multiple nuclei as a result of fusing the lipid bilayers that surround each nuclei.	tmpzr1t_l9r_go_relaxed.owl	nuclear fusion during karyogamy|nuclear fusion				Wikipedia:Karyogamy							GO:0007335		biological_process											owl:Class	
GO:0019405	biolink:NamedThing	alditol catabolic process	The chemical reactions and pathways resulting in the breakdown of alditols, any polyhydric alcohol derived from the acyclic form of a monosaccharide by reduction of its aldehyde or keto group to an alcoholic group.	tmpzr1t_l9r_go_relaxed.owl	alditol degradation|alditol catabolism|alditol breakdown													biological_process											owl:Class	
GO:0097365	biolink:NamedThing	stretch-activated, cation-selective, calcium channel activity involved in regulation of cardiac muscle cell action potential	Enables the transmembrane transfer of a calcium ion by a channel that opens in response to a mechanical stress in the form of stretching, and contributing to the regulation of action potential in a cardiac muscle cell.	tmpzr1t_l9r_go_relaxed.owl								pr	2012-07-26T02:39:10Z					molecular_function											owl:Class	
GO:0015275	biolink:NamedThing	stretch-activated, cation-selective, calcium channel activity	Enables the transmembrane transfer of a calcium ion by a channel that opens in response to a mechanical stress in the form of stretching.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0048269	biolink:NamedThing	methionine adenosyltransferase complex	A multimeric enzyme complex composed of variable numbers of catalytic alpha subunits, and noncatalytic beta subunits. The beta subunits are believed to have a regulatory function. The enzyme complex catalyzes the synthesis of S-adenosylmethionine (AdoMet), which is the major methyl group donor, participating in the methylation of proteins, DNA, RNA, phospholipids, and other small molecules.	tmpzr1t_l9r_go_relaxed.owl	MAT complex													cellular_component											owl:Class	
GO:0019182	biolink:NamedThing	histamine-gated chloride channel activity	Enables the transmembrane transfer of a chloride ion by a channel that opens when histamine has been bound by the channel complex or one of its constituent parts.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0005254	biolink:NamedThing	chloride channel activity	Enables the facilitated diffusion of a chloride (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-427570|Reactome:R-HSA-2744349|Reactome:R-HSA-975449|Reactome:R-HSA-975340									molecular_function											owl:Class	
GO:0043379	biolink:NamedThing	memory T cell differentiation	The process in which a newly activated T cell acquires specialized features of a memory T cell.	tmpzr1t_l9r_go_relaxed.owl	memory T-lymphocyte differentiation|memory T cell development|memory T-cell differentiation|memory T lymphocyte differentiation					Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.								biological_process											owl:Class	
GO:0090715	biolink:NamedThing	immunological memory formation process	Any immunological memory process that can contribute to the formation of immunological memory.	tmpzr1t_l9r_go_relaxed.owl								tb	2016-11-11T12:25:47Z					biological_process											owl:Class	
GO:0017003	biolink:NamedThing	protein-heme linkage	The covalent linkage of heme and a protein.	tmpzr1t_l9r_go_relaxed.owl	protein-haem linkage													biological_process											owl:Class	
GO:0017006	biolink:NamedThing	protein-tetrapyrrole linkage	The covalent linking of a tetrapyrrole to a protein.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0048743	biolink:NamedThing	positive regulation of skeletal muscle fiber development	Any process that activates, maintains or increases the rate of skeletal muscle fiber development. Muscle fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of skeletal myofiber development|stimulation of skeletal muscle fiber development|up-regulation of skeletal muscle fiber development|activation of skeletal muscle fiber development|upregulation of skeletal muscle fiber development|positive regulation of skeletal muscle fibre development|positive regulation of skeletal myofibre development|up regulation of skeletal muscle fiber development													biological_process											owl:Class	
GO:0014836	biolink:NamedThing	myoblast fate commitment involved in skeletal muscle regeneration	The process in which the developmental fate of a satellite cell becomes restricted such that it will develop into a myoblast. This occurs as part of skeletal muscle regeneration. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0048625	biolink:NamedThing	myoblast fate commitment	The process in which the developmental fate of a cell becomes restricted such that it will develop into a myoblast. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0035918	biolink:NamedThing	negative regulation of voltage-gated calcium channel activity in other organism	Any process in which an organism stops, prevents or reduces the frequency, rate or extent of the activity of a voltage-gated calcium channel in another organism. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of voltage-sensitive calcium channel activity in other organism|negative regulation of voltage-dependent calcium channel activity in other organism|downregulation of voltage-gated calcium channel activity in other organism|down-regulation of voltage-gated calcium channel activity in other organism|negative regulation of voltage gated calcium channel activity in other organism|inhibition of voltage-gated calcium channel activity in other organism							bf	2011-07-01T11:54:43Z					biological_process											owl:Class	
GO:0035917	biolink:NamedThing	negative regulation of calcium channel activity in other organism	Any process in which an organism stops, prevents or reduces the frequency, rate or extent of the activity of a calcium channel in another organism.	tmpzr1t_l9r_go_relaxed.owl	inhibition of calcium channel activity in other organism|downregulation of calcium channel activity in other organism|down-regulation of calcium channel activity in other organism							bf	2011-07-01T11:52:55Z					biological_process											owl:Class	
GO:0102787	biolink:NamedThing	caffeoyl-CoA:pelargonidin-3-O-beta-D-glucoside-6''-O-acyltransferase activity	Catalysis of the reaction: pelargonidin 3-O-beta-D-glucoside + caffeoyl-CoA = pelargonidin 3-O-beta-D-caffeoylglucoside + coenzyme A.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-7997									molecular_function											owl:Class	
GO:0033178	biolink:NamedThing	proton-transporting two-sector ATPase complex, catalytic domain	A protein complex that forms part of a proton-transporting two-sector ATPase complex and catalyzes ATP hydrolysis or synthesis. The catalytic domain (F1, V1, or A1) comprises a hexameric catalytic core and a central stalk, and is peripherally associated with the membrane when the two-sector ATPase is assembled.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:1904944	biolink:NamedThing	positive regulation of cardiac ventricle formation	Any process that activates or increases the frequency, rate or extent of cardiac ventricle formation.	tmpzr1t_l9r_go_relaxed.owl	up regulation of cardiac ventricle formation|activation of cardiac ventricle formation|upregulation of cardiac ventricle formation|up-regulation of cardiac ventricle formation							bc	2016-02-02T16:37:31Z					biological_process											owl:Class	
GO:2000176	biolink:NamedThing	positive regulation of pro-T cell differentiation	Any process that activates or increases the frequency, rate or extent of pro-T cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of pro-T lymphocyte differentiation							mah	2010-10-11T10:24:35Z					biological_process											owl:Class	
GO:0032925	biolink:NamedThing	regulation of activin receptor signaling pathway	Any process that modulates the frequency, rate or extent of the activity of any activin receptor signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	regulation of activin signaling pathway|regulation of activin signalling pathway|regulation of activin receptor signalling pathway													biological_process											owl:Class	
GO:0042220	biolink:NamedThing	response to cocaine	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cocaine stimulus. Cocaine is a crystalline alkaloid obtained from the leaves of the coca plant.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0021702	biolink:NamedThing	cerebellar Purkinje cell differentiation	The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature cerebellar Purkinje cell. Differentiation includes the processes involved in commitment of a neuroblast to a Purkinje cell fate. A Purkinje cell is an inhibitory GABAergic neuron found in the cerebellar cortex that projects to the deep cerebellar nuclei and brain stem.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:2000916	biolink:NamedThing	negative regulation of glucuronoxylan catabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of glucuronoxylan catabolic process.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of glucuronoxylan catabolism							tt	2011-07-29T07:54:44Z					biological_process											owl:Class	
GO:2001001	biolink:NamedThing	negative regulation of xylan catabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of xylan catabolic process.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of xylan catabolism|negative regulation of xylan degradation|negative regulation of xylan breakdown							tt	2011-08-08T03:23:18Z					biological_process											owl:Class	
GO:1990580	biolink:NamedThing	regulation of cytoplasmic translational termination	Any process that modulates the frequency, rate or extent of cytoplasmic translational termination.	tmpzr1t_l9r_go_relaxed.owl								vw	2014-12-10T15:48:55Z					biological_process											owl:Class	
GO:0019048	biolink:NamedThing	modulation by virus of host process	The process in which a virus effects a change in the structure or processes of its host organism.	tmpzr1t_l9r_go_relaxed.owl	modulation by virus of host anatomy or process|disruption by virus of host cell|viral interaction with host|virus-host interaction|modulation by virus of host morphology or physiology|host-virus interaction|modulation by virus of host anatomical structure or process|viral-host process|virus-host process	https://github.com/geneontology/go-ontology/issues/18605|https://github.com/geneontology/go-ontology/issues/18719			VZ:886			jl	2012-08-01T13:41:00Z			GO:0044661|GO:0044792		biological_process											owl:Class	
GO:0090461	biolink:NamedThing	glutamate homeostasis	Any process involved in the maintenance of an internal steady state of glutamate within an organism or cell.	tmpzr1t_l9r_go_relaxed.owl								tb	2012-09-24T14:22:02Z					biological_process											owl:Class	
GO:0009785	biolink:NamedThing	blue light signaling pathway	The series of molecular signals initiated upon sensing of blue light by photoreceptor molecule, at a wavelength between 400nm and 470nm.	tmpzr1t_l9r_go_relaxed.owl	blue light signalling pathway													biological_process											owl:Class	
GO:0030522	biolink:NamedThing	intracellular receptor signaling pathway	Any series of molecular signals initiated by a ligand binding to an receptor located within a cell.	tmpzr1t_l9r_go_relaxed.owl	intracellular receptor-mediated signalling pathway|intracellular receptor-mediated signaling pathway|intracellular receptor mediated signaling pathway													biological_process											owl:Class	
GO:0043133	biolink:NamedThing	hindgut contraction	A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the hindgut. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The hindgut is the posterior part of the alimentary canal, including the rectum, and the large intestine.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0022600	biolink:NamedThing	digestive system process	A physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0110128	biolink:NamedThing	phloem sucrose unloading	The process of unloading sucrose that is produced in the source tissues, from the sieve tube or companion cell of the phloem into the sink tissues.	tmpzr1t_l9r_go_relaxed.owl								kmv	2018-09-07T21:38:52Z					biological_process											owl:Class	
GO:0015770	biolink:NamedThing	sucrose transport	The directed movement of sucrose into, out of or within a cell, or between cells by means of some agent such as a transporter or pore. Sucrose is the disaccharide fructofuranosyl-glucopyranoside.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0097424	biolink:NamedThing	nucleolus-associated heterochromatin	Dense particles of heterochromatin, consisting of a loosely twisted strand about 600 Angstrom thick, found associated with the nucleolus.	tmpzr1t_l9r_go_relaxed.owl					NIF_Subcellular:sao1210952635			pr	2012-11-07T13:43:17Z					cellular_component											owl:Class	
GO:0030874	biolink:NamedThing	nucleolar chromatin	The portion of nuclear chromatin associated with the nucleolus; includes the DNA encoding the ribosomal RNA.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0042366	biolink:NamedThing	cobalamin catabolic process	The chemical reactions and pathways resulting in the breakdown of cobalamin (vitamin B12), a water-soluble vitamin characterized by possession of a corrin nucleus containing a cobalt atom.	tmpzr1t_l9r_go_relaxed.owl	vitamin B12 catabolism|vitamin B12 catabolic process|cobalamin breakdown|cobalamin degradation|cobalamin catabolism													biological_process											owl:Class	
GO:0042365	biolink:NamedThing	water-soluble vitamin catabolic process	The chemical reactions and pathways resulting in the breakdown of any of a diverse group of vitamins that are soluble in water.	tmpzr1t_l9r_go_relaxed.owl	water-soluble vitamin breakdown|water-soluble vitamin catabolism|water-soluble vitamin degradation													biological_process											owl:Class	
GO:0007098	biolink:NamedThing	centrosome cycle	The cell cycle process in which centrosome duplication and separation takes place. The centrosome cycle can operate with a considerable degree of independence from other processes of the cell cycle.	tmpzr1t_l9r_go_relaxed.owl	centrosome organisation|centrosome organization and biogenesis|centrosome organization											GO:0051297		biological_process											owl:Class	
GO:0006734	biolink:NamedThing	NADH metabolic process	The chemical reactions and pathways involving reduced nicotinamide adenine dinucleotide (NADH), a coenzyme present in most living cells and derived from the B vitamin nicotinic acid.	tmpzr1t_l9r_go_relaxed.owl	reduced nicotinamide adenine dinucleotide metabolic process|reduced nicotinamide adenine dinucleotide metabolism|reduced NAD metabolism|NAD (reduced) metabolic process|NAD (reduced) metabolism|NADH metabolism|reduced NAD metabolic process													biological_process											owl:Class	
GO:0008152	biolink:NamedThing	metabolic process	The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation.	tmpzr1t_l9r_go_relaxed.owl	metabolism resulting in cell growth|single-organism metabolic process|multicellular organism metabolic process|metabolic process resulting in cell growth|metabolism				Wikipedia:Metabolism	Note that metabolic processes do not include single functions or processes such as protein-protein interactions, protein-nucleic acids, nor receptor-ligand interactions.		jl	2012-10-17T15:46:40Z			GO:0044710|GO:0044236		biological_process											owl:Class	
GO:1902708	biolink:NamedThing	response to plumbagin	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a plumbagin stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2014-02-20T13:49:54Z					biological_process											owl:Class	
GO:0071667	biolink:NamedThing	DNA/RNA hybrid binding	Binding to a RNA/DNA hybrid.	tmpzr1t_l9r_go_relaxed.owl	RNA/DNA hybrid binding							mah	2010-02-15T01:51:44Z					molecular_function											owl:Class	
GO:0003676	biolink:NamedThing	nucleic acid binding	Binding to a nucleic acid.	tmpzr1t_l9r_go_relaxed.owl	base pairing											GO:0000496		molecular_function											owl:Class	
GO:1900881	biolink:NamedThing	18-methylnonadec-1-ene biosynthetic process	The chemical reactions and pathways resulting in the formation of 18-methylnonadec-1-ene.	tmpzr1t_l9r_go_relaxed.owl	18-methylnonadec-1-ene synthesis|18-methylnonadec-1-ene biosynthesis|18-methylnonadec-1-ene formation|18-methylnonadec-1-ene anabolism							tt	2012-06-13T02:26:55Z					biological_process											owl:Class	
GO:0043450	biolink:NamedThing	alkene biosynthetic process	The chemical reactions and pathways resulting in the formation of an alkene, any acyclic branched or unbranched hydrocarbon having one carbon-carbon double bond and the general formula CnH2n.	tmpzr1t_l9r_go_relaxed.owl	alkene biosynthesis|alkene anabolism|alkene synthesis|alkene formation													biological_process											owl:Class	
GO:1905343	biolink:NamedThing	regulation of cohesin unloading	Any process that modulates the frequency, rate or extent of cohesin unloading.	tmpzr1t_l9r_go_relaxed.owl								vw	2016-07-29T10:17:50Z					biological_process											owl:Class	
GO:0015516	biolink:NamedThing	tartrate:succinate antiporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: tartrate(out) + succinate(in) = tartrate(in) + succinate(out).	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0019216	biolink:NamedThing	regulation of lipid metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving lipids.	tmpzr1t_l9r_go_relaxed.owl	regulation of lipid metabolism													biological_process											owl:Class	
GO:0062027	biolink:NamedThing	positive regulation of SCF-dependent proteasomal ubiquitin-dependent catabolic process	Any process that starts or increases the rate, frequency or extent of SCF-dependent proteasomal ubiquitin-dependent protein catabolic process, the chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, with ubiquitin-protein ligation catalyzed by an SCF (Skp1/Cul1/F-box protein) complex, and mediated by the proteasome.	tmpzr1t_l9r_go_relaxed.owl								dph	2018-04-16T14:05:19Z					biological_process											owl:Class	
GO:0006553	biolink:NamedThing	lysine metabolic process	The chemical reactions and pathways involving lysine, 2,6-diaminohexanoic acid.	tmpzr1t_l9r_go_relaxed.owl	lysine metabolism				Wikipedia:Lysine									biological_process											owl:Class	
GO:0047884	biolink:NamedThing	FAD diphosphatase activity	Catalysis of the reaction: FAD + H2O = AMP + FMN.	tmpzr1t_l9r_go_relaxed.owl	riboflavin adenine dinucleotide pyrophosphatase activity|flavin adenine dinucleotide pyrophosphatase activity|riboflavine adenine dinucleotide pyrophosphatase activity|FAD nucleotidohydrolase activity|FAD pyrophosphatase activity|flavine adenine dinucleotide pyrophosphatase activity|FAD pyrophosphohydrolase activity				EC:3.6.1.18|MetaCyc:FAD-PYROPHOSPHATASE-RXN|RHEA:13889									molecular_function											owl:Class	
GO:0004551	biolink:NamedThing	nucleotide diphosphatase activity	Catalysis of the reaction: a dinucleotide + H2O = 2 mononucleotides.	tmpzr1t_l9r_go_relaxed.owl	nucleotide-sugar pyrophosphatase activity|dinucleotide nucleotidohydrolase activity|nucleotide pyrophosphatase activity				Reactome:R-HSA-196955|EC:3.6.1.9|MetaCyc:NUCLEOTIDE-PYROPHOSPHATASE-RXN									molecular_function											owl:Class	
GO:0100045	biolink:NamedThing	negative regulation of arginine catabolic process by transcription from RNA polymerase II promoter	Any transcription from RNA polymerase II promoter process that negatively regulates arginine catabolic process.	tmpzr1t_l9r_go_relaxed.owl								cjm	2015-04-02T04:13:19Z					biological_process											owl:Class	
GO:0006366	biolink:NamedThing	transcription by RNA polymerase II	The synthesis of RNA from a DNA template by RNA polymerase II (RNAP II), originating at an RNA polymerase II promoter. Includes transcription of messenger RNA (mRNA) and certain small nuclear RNAs (snRNAs).	tmpzr1t_l9r_go_relaxed.owl	transcription from RNA polymerase II promoter|transcription from Pol II promoter|RNA polymerase II transcription factor activity|general transcription from RNA polymerase II promoter|specific transcription from RNA polymerase II promoter|gene-specific transcription from RNA polymerase II promoter	https://github.com/geneontology/go-ontology/issues/14854										GO:0032569|GO:0032568		biological_process											owl:Class	
GO:1903645	biolink:NamedThing	negative regulation of chaperone-mediated protein folding	Any process that stops, prevents or reduces the frequency, rate or extent of chaperone-mediated protein folding.	tmpzr1t_l9r_go_relaxed.owl	down regulation of chaperone-mediated protein folding|inhibition of chaperone-mediated protein folding|down-regulation of chaperone-mediated protein folding|downregulation of chaperone-mediated protein folding							pga	2014-11-21T15:25:35Z					biological_process											owl:Class	
GO:1903644	biolink:NamedThing	regulation of chaperone-mediated protein folding	Any process that modulates the frequency, rate or extent of chaperone-mediated protein folding.	tmpzr1t_l9r_go_relaxed.owl								pga	2014-11-21T15:25:27Z					biological_process											owl:Class	
GO:0014826	biolink:NamedThing	vein smooth muscle contraction	A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the vein. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The vein is a vessel carrying blood away from the capillary beds.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0014829	biolink:NamedThing	vascular associated smooth muscle contraction	A process, occurring in the vascular tissue, whereby actin/myosin complex activity generates force through ATP hydrolysis resulting in a change in smooth muscle geometry. This process is always coupled to chemo-mechanical energy conversion.	tmpzr1t_l9r_go_relaxed.owl	vascular smooth muscle contraction													biological_process											owl:Class	
GO:2000810	biolink:NamedThing	regulation of bicellular tight junction assembly	Any process that modulates the frequency, rate or extent of tight junction assembly.	tmpzr1t_l9r_go_relaxed.owl	regulation of tight junction formation							vk	2011-07-06T01:08:28Z					biological_process											owl:Class	
GO:0031023	biolink:NamedThing	microtubule organizing center organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a microtubule organizing center, a structure from which microtubules grow.	tmpzr1t_l9r_go_relaxed.owl	microtubule organizing center organization and biogenesis|microtubule organising center organisation													biological_process											owl:Class	
GO:0043545	biolink:NamedThing	molybdopterin cofactor metabolic process	The chemical reactions and pathways involving the molybdopterin cofactor (Moco), essential for the catalytic activity of some enzymes, e.g. sulfite oxidase, xanthine dehydrogenase, and aldehyde oxidase. The cofactor consists of a mononuclear molybdenum (Mo-molybdopterin) or tungsten ion (W-molybdopterin) coordinated by one or two molybdopterin ligands.	tmpzr1t_l9r_go_relaxed.owl	molybdopterin cofactor metabolism|Moco metabolic process|Moco metabolism													biological_process											owl:Class	
GO:0051189	biolink:NamedThing	prosthetic group metabolic process	The chemical reactions and pathways involving a prosthetic group, the non-amino acid portion of certain protein molecules. Prosthetic groups may be inorganic or organic and are usually required for the biological activity of the protein.	tmpzr1t_l9r_go_relaxed.owl	coenzyme and prosthetic group metabolic process|coenzyme and prosthetic group metabolism|prosthetic group metabolism													biological_process											owl:Class	
GO:0008392	biolink:NamedThing	arachidonic acid epoxygenase activity	Catalysis of an NADPH- and oxygen-dependent reaction that converts arachidonic acid to a cis-epoxyeicosatrienoic acid.	tmpzr1t_l9r_go_relaxed.owl	cytochrome P450 CYP2J6|cytochrome P450 CYP2J5				Reactome:R-HSA-211983									molecular_function											owl:Class	
GO:0008391	biolink:NamedThing	arachidonic acid monooxygenase activity	Catalysis of the incorporation of one atom from molecular oxygen into arachidonic acid and the reduction of the other atom of oxygen to water.	tmpzr1t_l9r_go_relaxed.owl	cytochrome P450 CYP2B19													molecular_function											owl:Class	
GO:1903390	biolink:NamedThing	positive regulation of synaptic vesicle uncoating	Any process that activates or increases the frequency, rate or extent of synaptic vesicle uncoating.	tmpzr1t_l9r_go_relaxed.owl	up regulation of synaptic vesicle uncoating|up-regulation of synaptic vesicle coat depolymerization|upregulation of synaptic vesicle coat depolymerization|activation of synaptic vesicle coat protein depolymerization|activation of synaptic vesicle uncoating|positive regulation of synaptic vesicle coat depolymerization|up regulation of synaptic vesicle coat protein depolymerization|upregulation of synaptic vesicle coat protein depolymerization|upregulation of synaptic vesicle uncoating|activation of synaptic vesicle coat depolymerization|positive regulation of synaptic vesicle coat protein depolymerization|up regulation of synaptic vesicle coat depolymerization|up-regulation of synaptic vesicle coat protein depolymerization|up-regulation of synaptic vesicle uncoating							pad	2014-08-27T10:03:10Z					biological_process											owl:Class	
GO:0052055	biolink:NamedThing	modulation by symbiont of host molecular function	The process in which an organism effects a change in the function of a host protein via a direct interaction. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	modification by symbiont of host molecular function|modification by symbiont of host protein function													biological_process											owl:Class	
GO:0005945	biolink:NamedThing	6-phosphofructokinase complex	A protein complex that possesses 6-phosphofructokinase activity; homodimeric, homooctameric, and allosteric homotetrameric forms are known.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:1900301	biolink:NamedThing	negative regulation of laminarabiose transport	Any process that stops, prevents or reduces the frequency, rate or extent of laminarabiose transport.	tmpzr1t_l9r_go_relaxed.owl	downregulation of laminarabiose transport|inhibition of laminarabiose transport|down-regulation of laminarabiose transport|down regulation of laminarabiose transport							tt	2012-04-05T07:57:28Z					biological_process											owl:Class	
GO:1900300	biolink:NamedThing	regulation of laminarabiose transport	Any process that modulates the frequency, rate or extent of laminarabiose transport.	tmpzr1t_l9r_go_relaxed.owl								tt	2012-04-05T07:57:19Z					biological_process											owl:Class	
GO:1902279	biolink:NamedThing	positive regulation of pancreatic amylase secretion by cholecystokinin signaling pathway	A cholecystokinin signaling pathway that results in positive regulation of pancreatic amylase secretion.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of pancreatic amylase secretion by cholecystokinin signaling pathway|cholecystokinin-mediated pancreatic amylase secretion|up regulation of pancreatic amylase secretion by cholecystokinin signaling pathway|CCK-mediated pancreatic amylase secretion|CCK-induced amylase release in pancreatic cell|activation of pancreatic amylase secretion by cholecystokinin signaling pathway|CCK-stimulated pancreatic amylase release|upregulation of pancreatic amylase secretion by cholecystokinin signaling pathway							bf	2013-07-03T16:02:40Z					biological_process											owl:Class	
GO:1902278	biolink:NamedThing	positive regulation of pancreatic amylase secretion	Any process that activates or increases the frequency, rate or extent of pancreatic amylase secretion.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of pancreatic amylase secretion|upregulation of pancreatic amylase secretion|activation of pancreatic amylase secretion|up regulation of pancreatic amylase secretion							bf	2013-07-03T12:15:31Z					biological_process											owl:Class	
GO:0033042	biolink:NamedThing	umami taste receptor activity	Combining with soluble umami compounds to initiate a change in cell activity. These receptors are responsible for the sense of umami taste, the savory taste of meats and other foods that are rich in glutamates.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0090681	biolink:NamedThing	GPCR taste receptor activity	A G protein-coupled receptor activity that is responsible for the sense of taste.	tmpzr1t_l9r_go_relaxed.owl	G-protein coupled taste receptor activity|G-protein-coupled taste receptor activity							tb	2016-05-20T15:47:18Z					molecular_function											owl:Class	
GO:0048439	biolink:NamedThing	flower morphogenesis	The process in which the anatomical structures of the flower are generated and organized.	tmpzr1t_l9r_go_relaxed.owl												GO:0048411		biological_process											owl:Class	
GO:0006116	biolink:NamedThing	NADH oxidation	A metabolic process that results in the oxidation of reduced nicotinamide adenine dinucleotide, NADH, to the oxidized form, NAD.	tmpzr1t_l9r_go_relaxed.owl	reduced NAD oxidation|NAD (reduced) oxidation|reduced NAD dehydrogenation|NADH dehydrogenation|reduced nicotinamide adenine dinucleotide oxidation|reduced nicotinamide adenine dinucleotide dehydrogenation|NAD (reduced) dehydrogenation													biological_process											owl:Class	
GO:0050671	biolink:NamedThing	positive regulation of lymphocyte proliferation	Any process that activates or increases the rate or extent of lymphocyte proliferation.	tmpzr1t_l9r_go_relaxed.owl	up regulation of lymphocyte proliferation|up-regulation of lymphocyte proliferation|stimulation of lymphocyte proliferation|upregulation of lymphocyte proliferation|activation of lymphocyte proliferation													biological_process											owl:Class	
GO:0032946	biolink:NamedThing	positive regulation of mononuclear cell proliferation	Any process that activates or increases the frequency, rate or extent of mononuclear cell proliferation.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of mononuclear cell proliferation|activation of mononuclear cell proliferation|positive regulation of peripheral blood mononuclear cell proliferation|upregulation of mononuclear cell proliferation|positive regulation of PBMC proliferation|up regulation of mononuclear cell proliferation|stimulation of mononuclear cell proliferation													biological_process											owl:Class	
GO:0061706	biolink:NamedThing	glycolytic process from sucrose through glucose and fructose	The chemical reactions and pathways resulting in the breakdown of sucrose into pyruvate through both glucose and fructose intermediates, with the concomitant production of a small amount of ATP and the reduction of NAD(P) to NAD(P)H. Glycolysis begins with the metabolism of a carbohydrate to generate products that can enter the pathway and ends with the production of pyruvate. Pyruvate may be converted to acetyl-coenzyme A, ethanol, lactate, or other small molecules.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:PWY-1042			dph	2015-06-11T13:40:32Z					biological_process											owl:Class	
GO:0061615	biolink:NamedThing	glycolytic process through fructose-6-phosphate	The chemical reactions and pathways resulting in the breakdown of a monosaccharide into pyruvate, occurring through a fructose-6-phosphate intermediate, with the concomitant production of ATP and NADH.	tmpzr1t_l9r_go_relaxed.owl	glycolysis through fructose-6-phosphate				MetaCyc:PWY-5484			dph	2014-04-08T10:08:49Z					biological_process											owl:Class	
GO:0042016	biolink:NamedThing	interleukin-20 receptor activity	Combining with interleukin-20 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	IL-20R|IL-20 receptor activity													molecular_function											owl:Class	
GO:0004896	biolink:NamedThing	cytokine receptor activity	Combining with a cytokine and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	interleukin receptor activity|hematopoietin/interferon-class (D200-domain) cytokine receptor activity|IL receptor											GO:0004907		molecular_function											owl:Class	
GO:0007036	biolink:NamedThing	vacuolar calcium ion homeostasis	Any process involved in the maintenance of an internal steady state of calcium ions in the vacuole or between a vacuole and its surroundings.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0055074	biolink:NamedThing	calcium ion homeostasis	Any process involved in the maintenance of an internal steady state of calcium ions within an organism or cell.	tmpzr1t_l9r_go_relaxed.owl	regulation of calcium ion concentration													biological_process											owl:Class	
GO:1901830	biolink:NamedThing	zeaxanthin bis(beta-D-glucoside) biosynthetic process	The chemical reactions and pathways resulting in the formation of zeaxanthin bis(beta-D-glucoside).	tmpzr1t_l9r_go_relaxed.owl	zeaxanthin bis(beta-D-glucoside) biosynthesis|zeaxanthin bis(beta-D-glucoside) formation|zeaxanthin bis(beta-D-glucoside) synthesis|zeaxanthin diglucoside formation|zeaxanthin diglucoside anabolism|zeaxanthin bis(beta-D-glucoside) anabolism|zeaxanthin diglucoside synthesis|zeaxanthin diglucoside biosynthesis							yaf	2013-01-22T12:32:10Z					biological_process											owl:Class	
GO:1901806	biolink:NamedThing	beta-glucoside biosynthetic process	The chemical reactions and pathways resulting in the formation of beta-glucoside.	tmpzr1t_l9r_go_relaxed.owl	beta-glucoside biosynthesis|beta-glucoside formation|beta-glucoside synthesis|beta-glucoside anabolism							yaf	2013-01-22T10:10:30Z					biological_process											owl:Class	
GO:1990314	biolink:NamedThing	cellular response to insulin-like growth factor stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin-like growth factor stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to insulin-like growth factor							sl	2014-03-07T19:38:21Z					biological_process											owl:Class	
GO:0071375	biolink:NamedThing	cellular response to peptide hormone stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide hormone stimulus. A peptide hormone is any of a class of peptides that are secreted into the blood stream and have endocrine functions in living animals.	tmpzr1t_l9r_go_relaxed.owl	cellular response to polypeptide hormone stimulus							mah	2009-12-11T03:24:18Z					biological_process											owl:Class	
GO:0019527	biolink:NamedThing	pentitol catabolic process	The chemical reactions and pathways resulting in the breakdown of pentitols, any alditol with a chain of five carbon atoms in the molecule.	tmpzr1t_l9r_go_relaxed.owl	pentitol breakdown|pentitol catabolism|pentitol degradation													biological_process											owl:Class	
GO:0044841	biolink:NamedThing	gut granule membrane	The membrane of a gut granule, a lysosome-related organelle contained within the intestinal cells of the nematode C. elegans.	tmpzr1t_l9r_go_relaxed.owl								jl	2014-03-25T12:02:05Z					cellular_component											owl:Class	
GO:0031090	biolink:NamedThing	organelle membrane	A membrane that is one of the two lipid bilayers of an organelle envelope or the outermost membrane of single membrane bound organelle.	tmpzr1t_l9r_go_relaxed.owl	intracellular membrane				NIF_Subcellular:sao830981606									cellular_component											owl:Class	
GO:2000122	biolink:NamedThing	negative regulation of stomatal complex development	Any process that stops, prevents, or reduces the frequency, rate or extent of stomatal complex development.	tmpzr1t_l9r_go_relaxed.owl								dhl	2010-09-27T08:28:26Z					biological_process											owl:Class	
GO:2000825	biolink:NamedThing	positive regulation of androgen receptor activity	Any process that activates or increases the frequency, rate or extent of androgen receptor activity.	tmpzr1t_l9r_go_relaxed.owl								yaf	2011-07-15T10:56:14Z					biological_process											owl:Class	
GO:1904812	biolink:NamedThing	rRNA acetylation involved in maturation of SSU-rRNA	Any rRNA acetylation that is involved in maturation of SSU-rRNA.	tmpzr1t_l9r_go_relaxed.owl	rRNA acetylation involved in processing of 20S pre-rRNA|rRNA acetylation involved in SSU-rRNA maturation							al	2015-11-11T15:38:41Z					biological_process											owl:Class	
GO:1990882	biolink:NamedThing	rRNA acetylation	The modification of rRNA structure by addition of an acetyl group to rRNA. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid.	tmpzr1t_l9r_go_relaxed.owl								al	2015-10-28T13:24:58Z					biological_process											owl:Class	
GO:0031609	biolink:NamedThing	cytosolic proteasome core complex, beta-subunit complex	The proteasome core subcomplex that constitutes the two inner rings of the cytosolic proteasome core complex.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0019774	biolink:NamedThing	proteasome core complex, beta-subunit complex	The proteasome core subcomplex that constitutes the two inner rings of the proteasome core complex. An example of this component is found in Mus musculus.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:1905028	biolink:NamedThing	negative regulation of membrane depolarization during AV node cell action potential	Any process that stops, prevents or reduces the frequency, rate or extent of membrane depolarization during AV node cell action potential.	tmpzr1t_l9r_go_relaxed.owl	inhibition of membrane depolarization during AV node cell action potential|down regulation of membrane depolarization during AV node cardiac muscle cell action potential|inhibition of membrane depolarization during atrioventricular node cardiac muscle cell action potential|down regulation of membrane depolarization during AV node cell action potential|down-regulation of membrane depolarization during AV node cardiac muscle cell action potential|negative regulation of membrane depolarization during AV node cardiac muscle cell action potential|down regulation of membrane depolarization during atrioventricular node cardiac muscle cell action potential|down-regulation of membrane depolarization during atrioventricular node cardiac muscle cell action potential|down-regulation of membrane depolarization during AV node cell action potential|downregulation of membrane depolarization during AV node cardiac muscle cell action potential|negative regulation of membrane depolarization during atrioventricular node cardiac muscle cell action potential|downregulation of membrane depolarization during AV node cell action potential|inhibition of membrane depolarization during AV node cardiac muscle cell action potential|downregulation of membrane depolarization during atrioventricular node cardiac muscle cell action potential							rph	2016-03-04T13:46:15Z					biological_process											owl:Class	
GO:1905027	biolink:NamedThing	regulation of membrane depolarization during AV node cell action potential	Any process that modulates the frequency, rate or extent of membrane depolarization during AV node cell action potential.	tmpzr1t_l9r_go_relaxed.owl	regulation of membrane depolarization during atrioventricular node cardiac muscle cell action potential|regulation of membrane depolarization during AV node cardiac muscle cell action potential							rph	2016-03-04T13:46:06Z					biological_process											owl:Class	
GO:0070425	biolink:NamedThing	negative regulation of nucleotide-binding oligomerization domain containing signaling pathway	Any process that stops, prevents, or reduces the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing (NOD) pathway.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of NOD signaling pathway|negative regulation of nucleotide-binding oligomerization domain containing signalling pathway													biological_process											owl:Class	
GO:1902532	biolink:NamedThing	negative regulation of intracellular signal transduction	Any process that stops, prevents or reduces the frequency, rate or extent of intracellular signal transduction.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of intracellular signal transduction pathway|negative regulation of intracellular signal transduction pathway|negative regulation of intracellular signaling cascade|down regulation of signal transduction via intracellular signaling cascade|downregulation of signal transmission via intracellular cascade|negative regulation of intracellular protein kinase cascade|negative regulation of intracellular signaling pathway|inhibition of intracellular signal transduction|down regulation of intracellular signaling pathway|down regulation of intracellular signaling chain|downregulation of intracellular signaling cascade|down regulation of intracellular signaling cascade|down-regulation of intracellular signal transduction|inhibition of signal transmission via intracellular cascade|down regulation of intracellular signal transduction pathway|down-regulation of signal transduction via intracellular signaling cascade|negative regulation of signal transduction via intracellular signaling cascade|negative regulation of signal transmission via intracellular cascade|down-regulation of intracellular signaling chain|downregulation of intracellular signal transduction pathway|down regulation of intracellular signal transduction|down-regulation of intracellular signaling pathway|down-regulation of intracellular signaling cascade|inhibition of intracellular signaling cascade|inhibition of intracellular signaling chain|inhibition of intracellular signaling pathway|inhibition of signal transduction via intracellular signaling cascade|down regulation of signal transmission via intracellular cascade|negative regulation of intracellular signaling chain|downregulation of signal transduction via intracellular signaling cascade|downregulation of intracellular signaling chain|down-regulation of signal transmission via intracellular cascade|downregulation of intracellular signaling pathway|downregulation of intracellular signal transduction|inhibition of intracellular signal transduction pathway							bf	2013-12-02T11:33:01Z			GO:0010741		biological_process											owl:Class	
GO:1904355	biolink:NamedThing	positive regulation of telomere capping	Any process that activates or increases the frequency, rate or extent of telomere capping.	tmpzr1t_l9r_go_relaxed.owl	activation of telomere end protection|activation of telomere capping|positive regulation of telomere end protection|up-regulation of telomere capping|upregulation of telomere end protection|up-regulation of telomere end protection|upregulation of telomere capping|up regulation of telomere capping|up regulation of telomere end protection							nc	2015-06-12T16:51:20Z					biological_process											owl:Class	
GO:1904353	biolink:NamedThing	regulation of telomere capping	Any process that modulates the frequency, rate or extent of telomere capping.	tmpzr1t_l9r_go_relaxed.owl	regulation of telomere end protection							nc	2015-06-12T16:51:08Z					biological_process											owl:Class	
GO:2000556	biolink:NamedThing	positive regulation of T-helper 1 cell cytokine production	Any process that activates or increases the frequency, rate or extent of T-helper 1 cell cytokine production.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of Th1 cell cytokine production							ebc	2011-04-03T07:35:56Z					biological_process											owl:Class	
GO:0032415	biolink:NamedThing	regulation of sodium:proton antiporter activity	Any process that modulates the activity of a sodium:hydrogen antiporter, which catalyzes the reaction: Na+(out) + H+(in) = Na+(in) + H+(out).	tmpzr1t_l9r_go_relaxed.owl	regulation of sodium:hydrogen antiporter activity													biological_process											owl:Class	
GO:0010155	biolink:NamedThing	regulation of proton transport	Any process that modulates the frequency, rate or extent of proton transport into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0010825	biolink:NamedThing	positive regulation of centrosome duplication	Any process that increases the frequency, rate or extent of centrosome duplication. Centrosome duplication is the replication of a centrosome, a structure comprised of a pair of centrioles and peri-centriolar material from which a microtubule spindle apparatus is organized.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1990042	biolink:NamedThing	glycerol dehydrogenase [NAD(P)+] activity	Catalysis of an oxidation-reduction (redox) reaction in which glycerol is converted into glycerone and NAD+ or NADP is reduced.	tmpzr1t_l9r_go_relaxed.owl	glycerol dehydrogenase activity, NAD or NADP as acceptor							rb	2013-02-14T00:34:45Z					molecular_function											owl:Class	
GO:0050977	biolink:NamedThing	magnetoreception by sensory perception of chemical stimulus	The series of events required for an organism to receive a chemical stimulus relating to a magnetic field, convert it to a molecular signal, and recognize and characterize the signal. It is believed that organisms such as birds and salamanders use a 'chemical compass': chemical reactions that involve transitions between different spin states can be influenced by magnetic fields and by detecting the different product ratios, these organisms can perceive the direction of the magnetic field. The mechanism by which this is detected is not certain but it may also involve light stimuli.	tmpzr1t_l9r_go_relaxed.owl	magnetoreception, sensory perception of chemical stimulus|magnetoreception by chemical stimulus|magnetoreception through chemical stimulus|magnetoreception, using chemical stimulus													biological_process											owl:Class	
GO:0007606	biolink:NamedThing	sensory perception of chemical stimulus	The series of events required for an organism to receive a sensory chemical stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.	tmpzr1t_l9r_go_relaxed.owl	chemosensory perception													biological_process											owl:Class	
GO:0006530	biolink:NamedThing	asparagine catabolic process	The chemical reactions and pathways resulting in the breakdown of asparagine, 2-amino-3-carbamoylpropanoic acid.	tmpzr1t_l9r_go_relaxed.owl	asparagine breakdown|asparagine degradation|asparagine catabolism													biological_process											owl:Class	
GO:0010733	biolink:NamedThing	positive regulation of protein glutathionylation	Any process that increases the rate, frequency, or extent of protein glutathionylation. Protein glutathionylation is the protein modification process in which a glutathione molecule is added to a protein amino acid through a disulfide linkage.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of protein amino acid glutathionylation													biological_process											owl:Class	
GO:0031401	biolink:NamedThing	positive regulation of protein modification process	Any process that activates or increases the frequency, rate or extent of the covalent alteration of one or more amino acid residues within a protein.	tmpzr1t_l9r_go_relaxed.owl	activation of protein modification|upregulation of protein modification|up-regulation of protein modification|up regulation of protein modification|stimulation of protein modification													biological_process											owl:Class	
GO:0039707	biolink:NamedThing	pore formation by virus in membrane of host cell	The aggregation, arrangement and bonding together of a set of components by a virus to form a pore complex in a membrane of a host organism.	tmpzr1t_l9r_go_relaxed.owl	pore formation in membrane of host cell by virus|viroporin							bf	2013-11-25T15:33:33Z					biological_process											owl:Class	
GO:1902395	biolink:NamedThing	regulation of 1-deoxy-D-xylulose-5-phosphate synthase activity	Any process that modulates the frequency, rate or extent of 1-deoxy-D-xylulose-5-phosphate synthase activity.	tmpzr1t_l9r_go_relaxed.owl	regulation of pyruvate:D-glyceraldehyde-3-phosphate acetaldehydetransferase (decarboxylating)|regulation of 1-deoxyxylulose-5-phosphate synthase activity|regulation of DXP-synthase activity|regulation of DOXP synthase activity|regulation of 1-deoxy-D-xylulose-5-phosphate pyruvate-lyase (carboxylating) activity							tb	2013-09-11T21:12:25Z					biological_process											owl:Class	
GO:0019674	biolink:NamedThing	NAD metabolic process	The chemical reactions and pathways involving nicotinamide adenine dinucleotide (NAD), a coenzyme present in most living cells and derived from the B vitamin nicotinic acid.	tmpzr1t_l9r_go_relaxed.owl	oxidized nicotinamide adenine dinucleotide metabolic process|oxidized NAD metabolism|NAD (oxidized) metabolism|nicotinamide adenine dinucleotide metabolic process|NAD phosphorylation and dephosphorylation|oxidized NAD metabolic process|nicotinamide adenine dinucleotide metabolism|oxidized nicotinamide adenine dinucleotide metabolism|NAD (oxidized) metabolic process|NAD metabolism													biological_process											owl:Class	
GO:0005034	biolink:NamedThing	osmosensor activity	Sensing extracellular osmolarity to initiate a change in cell activity, and spanning the membrane of the cell.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0032530	biolink:NamedThing	regulation of microvillus organization	Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a microvillus.	tmpzr1t_l9r_go_relaxed.owl	regulation of microvillus organization and biogenesis|regulation of microvillus organisation													biological_process											owl:Class	
GO:0120035	biolink:NamedThing	regulation of plasma membrane bounded cell projection organization	Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of plasma membrane bounded cell projections.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/13298						krc	2017-04-26T16:02:06Z					biological_process											owl:Class	
GO:1900470	biolink:NamedThing	positive regulation of phosphatidylserine biosynthetic process	Any process that activates or increases the frequency, rate or extent of phosphatidylserine biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	up regulation of phosphatidylserine biosynthesis|up-regulation of phosphatidylserine anabolism|positive regulation of phosphatidylserine biosynthesis|up-regulation of phosphatidylserine biosynthesis|up-regulation of phosphatidylserine synthesis|activation of phosphatidylserine biosynthesis|activation of phosphatidylserine synthesis|upregulation of phosphatidylserine anabolism|up regulation of phosphatidylserine formation|activation of phosphatidylserine biosynthetic process|upregulation of phosphatidylserine biosynthesis|positive regulation of phosphatidylserine synthesis|up regulation of phosphatidylserine anabolism|up regulation of phosphatidylserine biosynthetic process|up-regulation of phosphatidylserine formation|up-regulation of phosphatidylserine biosynthetic process|up regulation of phosphatidylserine synthesis|activation of phosphatidylserine formation|positive regulation of phosphatidylserine anabolism|positive regulation of phosphatidylserine formation|upregulation of phosphatidylserine synthesis|activation of phosphatidylserine anabolism|upregulation of phosphatidylserine biosynthetic process|upregulation of phosphatidylserine formation							dgf	2012-05-01T08:01:19Z					biological_process											owl:Class	
GO:1900468	biolink:NamedThing	regulation of phosphatidylserine biosynthetic process	Any process that modulates the frequency, rate or extent of phosphatidylserine biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of phosphatidylserine biosynthesis|regulation of phosphatidylserine synthesis|regulation of phosphatidylserine anabolism|regulation of phosphatidylserine formation							dgf	2012-05-01T08:01:01Z					biological_process											owl:Class	
GO:0032075	biolink:NamedThing	positive regulation of nuclease activity	Any process that activates or increases the frequency, rate or extent of nuclease activity, the hydrolysis of ester linkages within nucleic acids.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of nuclease activity|stimulation of nuclease activity|activation of nuclease activity|upregulation of nuclease activity|up regulation of nuclease activity|nuclease activator													biological_process											owl:Class	
GO:0009956	biolink:NamedThing	radial pattern formation	The regionalization process that results in defined areas around a point in which specific types of cell differentiation will occur.	tmpzr1t_l9r_go_relaxed.owl	radial pattern specification													biological_process											owl:Class	
GO:0009635	biolink:NamedThing	response to herbicide	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a herbicide stimulus. Herbicides are chemicals used to kill or control the growth of plants.	tmpzr1t_l9r_go_relaxed.owl	herbicide susceptibility/resistance													biological_process											owl:Class	
GO:1905570	biolink:NamedThing	positive regulation of ferrichrome biosynthetic process	Any process that activates or increases the frequency, rate or extent of ferrichrome biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	up regulation of ferrichrome biosynthesis|upregulation of ferrichrome biosynthesis|up-regulation of ferrichrome biosynthetic process, peptide modification|up-regulation of ferrichrome biosynthetic process, peptide formation|activation of ferrichrome synthesis|activation of ferrichrome formation|up regulation of ferrichrome biosynthetic process, peptide formation|up-regulation of ferrichrome formation|activation of ferrichrome biosynthetic process, peptide formation|up regulation of ferrichrome anabolism|upregulation of ferrichrome biosynthetic process, peptide modification|up regulation of ferrichrome biosynthetic process, peptide modification|up-regulation of ferrichrome biosynthesis|positive regulation of ferrichrome biosynthesis|up regulation of ferrichrome formation|positive regulation of ferrichrome anabolism|up regulation of ferrichrome biosynthetic process|upregulation of ferrichrome synthesis|positive regulation of ferrichrome formation|activation of ferrichrome biosynthesis|upregulation of ferrichrome biosynthetic process, peptide formation|up-regulation of ferrichrome biosynthetic process|up-regulation of ferrichrome anabolism|positive regulation of ferrichrome synthesis|positive regulation of ferrichrome biosynthetic process, peptide modification|up-regulation of ferrichrome synthesis|upregulation of ferrichrome formation|up regulation of ferrichrome synthesis|upregulation of ferrichrome anabolism|activation of ferrichrome biosynthetic process, peptide modification|upregulation of ferrichrome biosynthetic process|activation of ferrichrome biosynthetic process|activation of ferrichrome anabolism|positive regulation of ferrichrome biosynthetic process, peptide formation							pr	2016-10-18T14:49:16Z					biological_process											owl:Class	
GO:1900706	biolink:NamedThing	positive regulation of siderophore biosynthetic process	Any process that activates or increases the frequency, rate or extent of siderophore biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of siderophore biosynthesis|up regulation of siderophore anabolism|upregulation of siderophore synthesis|activation of siderochrome biosynthesis|activation of siderophore biosynthetic process|up-regulation of siderochrome biosynthetic process|activation of siderophore anabolism|upregulation of siderochrome biosynthesis|up-regulation of siderophore biosynthetic process, peptide modification|upregulation of siderochrome biosynthetic process|up regulation of siderophore formation|up-regulation of siderochrome biosynthesis|activation of siderophore synthesis|up-regulation of siderophore biosynthetic process|up-regulation of siderophore anabolism|up-regulation of siderophore biosynthetic process, peptide formation|positive regulation of siderochrome biosynthesis|positive regulation of siderophore anabolism|positive regulation of siderophore biosynthetic process, peptide formation|upregulation of siderophore biosynthetic process|upregulation of siderophore biosynthetic process, peptide modification|upregulation of siderophore biosynthesis|up regulation of siderophore biosynthetic process, peptide formation|upregulation of siderophore anabolism|positive regulation of siderophore synthesis|activation of siderophore biosynthetic process, peptide modification|upregulation of siderophore formation|up regulation of siderochrome biosynthesis|activation of siderophore biosynthetic process, peptide formation|positive regulation of siderophore formation|upregulation of siderophore biosynthetic process, peptide formation|activation of siderophore formation|up regulation of siderophore biosynthetic process|positive regulation of siderophore biosynthetic process, peptide modification|activation of siderophore biosynthesis|up regulation of siderophore biosynthesis|up regulation of siderophore synthesis|up regulation of siderophore biosynthetic process, peptide modification|positive regulation of siderophore biosynthesis|activation of siderochrome biosynthetic process|up-regulation of siderophore synthesis|up-regulation of siderophore formation|positive regulation of siderochrome biosynthetic process|up regulation of siderochrome biosynthetic process							di	2012-05-22T05:00:00Z					biological_process											owl:Class	
GO:0050538	biolink:NamedThing	N-carbamoyl-L-amino-acid hydrolase activity	Catalysis of the reaction: N-carbamoyl-L-2-amino acid + H2O = L-2-amino acid + NH3 + CO2. The N-carbamoyl-L-2-amino acid is a 2-ureido carboxylate.	tmpzr1t_l9r_go_relaxed.owl	L-carbamoylase activity|N-carbamoyl-L-amino acid amidohydrolase activity				RHEA:17581|MetaCyc:3.5.1.87-RXN|EC:3.5.1.87									molecular_function											owl:Class	
GO:1901926	biolink:NamedThing	cadinene metabolic process	The chemical reactions and pathways involving cadinene.	tmpzr1t_l9r_go_relaxed.owl	cadinene metabolism							ms	2013-02-18T14:54:22Z					biological_process											owl:Class	
GO:0051761	biolink:NamedThing	sesquiterpene metabolic process	The chemical reactions and pathways involving sesquiterpenes, any of a class of terpenes of the formula C15H24 or a derivative of such a terpene.	tmpzr1t_l9r_go_relaxed.owl	sesquiterpene metabolism													biological_process											owl:Class	
GO:0044267	biolink:NamedThing	cellular protein metabolic process	The chemical reactions and pathways involving a specific protein, rather than of proteins in general, occurring at the level of an individual cell. Includes cellular protein modification.	tmpzr1t_l9r_go_relaxed.owl	cellular protein metabolism													biological_process											owl:Class	
GO:0061868	biolink:NamedThing	hepatic stellate cell migration	The orderly movement of a hepatic stellate cell from one site to another.	tmpzr1t_l9r_go_relaxed.owl								dph	2017-05-01T13:01:40Z					biological_process											owl:Class	
GO:0010761	biolink:NamedThing	fibroblast migration	Cell migration that is accomplished by extension and retraction of a fibroblast pseudopodium. A fibroblast is a connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules.	tmpzr1t_l9r_go_relaxed.owl	fibroblast cell migration													biological_process											owl:Class	
GO:0097643	biolink:NamedThing	amylin receptor activity	Combining with amylin to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl								pr	2014-09-08T15:34:16Z					molecular_function											owl:Class	
GO:0097642	biolink:NamedThing	calcitonin family receptor activity	Combining with any member of the calcitonin family (e.g. adrenomedullin, adrenomedullin 2 (intermedin), amylin, calcitonin and calcitonin gene-related peptides (CGRPs)) to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl								pr	2014-09-08T15:32:19Z					molecular_function											owl:Class	
GO:0018879	biolink:NamedThing	biphenyl metabolic process	The chemical reactions and pathways involving biphenyl, a toxic aromatic hydrocarbon used as a heat transfer agent, as a fungistat in packaging citrus fruits and in plant disease control. Biphenyl can be chlorinated with 1-10 chlorine molecules to form polychlorinated biphenyls (PCBs).	tmpzr1t_l9r_go_relaxed.owl	xenene metabolism|biphenyl metabolism|xenene metabolic process				UM-BBD_pathwayID:bph									biological_process											owl:Class	
GO:0062103	biolink:NamedThing	double-stranded RNA biosynthetic process	The chemical reactions and pathways resulting in the formation of double-stranded RNA.	tmpzr1t_l9r_go_relaxed.owl	double-stranded RNA biosynthesis|dsRNA biosynthetic process|dsRNA biosynthesis							dph	2019-01-07T13:29:47Z					biological_process											owl:Class	
GO:0097517	biolink:NamedThing	contractile actin filament bundle	An actin filament bundle in which the filaments are loosely packed (approximately 30-60 nm apart) and arranged with opposing polarities; the loose packing allows myosin (usually myosin-II) to enter the bundle.	tmpzr1t_l9r_go_relaxed.owl								pr	2013-10-16T15:41:14Z					cellular_component											owl:Class	
GO:0032432	biolink:NamedThing	actin filament bundle	An assembly of actin filaments that are on the same axis but may be oriented with the same or opposite polarities and may be packed with different levels of tightness.	tmpzr1t_l9r_go_relaxed.owl	actin cable											GO:0030482|GO:0000141		cellular_component											owl:Class	
GO:0022873	biolink:NamedThing	protein-N(PI)-phosphohistidine-maltose phosphotransferase system transporter activity	Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + maltose(out) = protein histidine + maltose phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.	tmpzr1t_l9r_go_relaxed.owl	maltose PTS transporter activity													molecular_function											owl:Class	
GO:0008982	biolink:NamedThing	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity	Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + sugar(out) = protein histidine + sugar phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.	tmpzr1t_l9r_go_relaxed.owl	sucrose phosphotransferase system II|protein-Npi-phospho-L-histidine:sugar N-pros-phosphotransferase activity|group translocator activity|PEP-dependent phosphotransferase enzyme II|protein-Npi-phosphohistidine-sugar phosphotransferase activity|protein-Npi-phospho-L-histidine:sugar Npi-phosphotransferase activity|gene glC proteins|phosphotransferase, phosphohistidinoprotein-hexose activity|enzyme IIl4ac|PTS transporter|protein-Np-phosphohistidine-sugar phosphotransferase activity|protein, specific or class, gene bglC|phosphohistidinoprotein-hexose phosphotransferase activity|phosphohistidinoprotein-hexose phosphoribosyltransferase activity|phosphotransfer-driven group translocator|PTS permease activity|phosphoenolpyruvate-sugar phosphotransferase enzyme II|PEP--sugar phosphotransferase enzyme II activity|ribonucleic acid formation factor, gene glC|phosphoprotein factor-hexose phosophotransferase activity|protein-Npi-phosphohistidine:sugar N-pros-phosphotransferase activity|enzyme II of the phosphotransferase system|gene bglC RNA formation factors				MetaCyc:2.7.1.69-RXN|EC:2.7.1.69							GO:0015455|GO:0015456		molecular_function											owl:Class	
GO:1900196	biolink:NamedThing	regulation of penicillin biosynthetic process	Any process that modulates the frequency, rate or extent of penicillin biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of penicillin anabolism|regulation of penicillin biosynthesis|regulation of penicillin formation|regulation of penicillin synthesis							di	2012-03-20T03:56:33Z					biological_process											owl:Class	
GO:0032268	biolink:NamedThing	regulation of cellular protein metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a protein, occurring at the level of an individual cell.	tmpzr1t_l9r_go_relaxed.owl	regulation of cellular protein metabolism													biological_process											owl:Class	
GO:0097040	biolink:NamedThing	phthiocerol biosynthetic process	The chemical reactions and pathways resulting in the formation of phthiocerol, a lipid-based 1,3-glycol consisting of (3S,4R)-3-methoxy-4-methylnonacosane having (9R)- and (11S)-hydroxy substituents.	tmpzr1t_l9r_go_relaxed.owl	phthiocerol formation|phthiocerol synthesis|phthiocerol biosynthesis|phthiocerol anabolism							pr	2011-04-15T01:18:17Z					biological_process											owl:Class	
GO:0042845	biolink:NamedThing	glycol biosynthetic process	The chemical reactions and pathways resulting in the formation of glycol, a diol in which the two hydroxy groups are on different carbon atoms, usually but not necessarily adjacent.	tmpzr1t_l9r_go_relaxed.owl	glycol anabolism|glycol formation|glycol biosynthesis|glycol synthesis|dihydric alcohol biosynthesis|dihydric alcohol biosynthetic process													biological_process											owl:Class	
GO:0001660	biolink:NamedThing	fever generation	The heat generation process that results in a rise in body temperature above the normal, often as a response to infection.	tmpzr1t_l9r_go_relaxed.owl	pyrexia				Wikipedia:Fever									biological_process											owl:Class	
GO:0006953	biolink:NamedThing	acute-phase response	An acute inflammatory response that involves non-antibody proteins whose concentrations in the plasma increase in response to infection or injury of homeothermic animals.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0097656	biolink:NamedThing	cell-cell self recognition	A cell-cell recognition process by which a cell distinguishes between self and non self during cooperative behavior, such as early development.	tmpzr1t_l9r_go_relaxed.owl	kin recognition|kin discrimination|self recognition					Examples are the membrane proteins TgrB1 and TgrC1 in the social amoeba Dictyostelium discoideum.		pr	2014-09-24T20:58:35Z					biological_process											owl:Class	
GO:0071376	biolink:NamedThing	cellular response to corticotropin-releasing hormone stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a corticotropin-releasing hormone stimulus. Corticotropin-releasing hormone is a peptide hormone involved in the stress response.	tmpzr1t_l9r_go_relaxed.owl	cellular response to corticotropin-releasing factor stimulus|cellular response to CRF stimulus|cellular response to corticoliberin stimulus|cellular response to CRH stimulus							mah	2009-12-11T03:24:56Z					biological_process											owl:Class	
GO:0043435	biolink:NamedThing	response to corticotropin-releasing hormone	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a corticotropin-releasing hormone stimulus. Corticotropin-releasing hormone is a peptide hormone involved in the stress response.	tmpzr1t_l9r_go_relaxed.owl	response to CRF stimulus|response to corticoliberin stimulus|response to CRH stimulus|response to corticotropin-releasing hormone stimulus|response to corticotropin-releasing factor stimulus													biological_process											owl:Class	
GO:0140346	biolink:NamedThing	phosphatidylserine flippase activity	Catalysis of the movement of phosphatidylserine from the exoplasmic to the cytosolic leaftlet of a membrane, using energy from the hydrolysis of ATP.	tmpzr1t_l9r_go_relaxed.owl	phosphatidylserine flippase activity (exoplasmic to cytosolic leaftlet)							pg	2019-05-16T13:44:23Z					molecular_function											owl:Class	
GO:0015247	biolink:NamedThing	aminophospholipid flippase activity	Enables the transfer of aminophospholipids from the exoplasmic to the cytosolic leaftlet of a membrane, using energy from the hydrolysis of ATP. Aminophospholipids contain phosphoric acid as a mono- or diester and an amino (NH2) group.	tmpzr1t_l9r_go_relaxed.owl	aminophospholipid transmembrane transporter activity|aminophospholipid transporter activity													molecular_function											owl:Class	
GO:0048330	biolink:NamedThing	positive regulation of axial mesodermal cell fate specification	Any process that activates or increases the frequency, rate or extent of axial mesoderm cell fate specification.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of axial mesodermal cell fate specification|activation of axial mesodermal cell fate specification|stimulation of axial mesodermal cell fate specification|upregulation of axial mesodermal cell fate specification|up regulation of axial mesodermal cell fate specification													biological_process											owl:Class	
GO:0048337	biolink:NamedThing	positive regulation of mesodermal cell fate specification	Any process that activates or increases the frequency, rate or extent of mesoderm cell fate specification.	tmpzr1t_l9r_go_relaxed.owl	up regulation of mesodermal cell fate specification|stimulation of mesodermal cell fate specification|upregulation of mesodermal cell fate specification|activation of mesodermal cell fate specification|up-regulation of mesodermal cell fate specification													biological_process											owl:Class	
GO:0032542	biolink:NamedThing	sulfiredoxin activity	Catalysis of the reaction: peroxiredoxin-(S-hydroxy-S-oxocysteine) + ATP + 2 R-SH = peroxiredoxin-(S-hydroxycysteine) + ADP + phosphate + R-S-S-R.	tmpzr1t_l9r_go_relaxed.owl	Srx1|peroxiredoxin-(S-hydroxy-S-oxocysteine) reductase activity|peroxiredoxin-(S-hydroxy-S-oxocysteine):thiol oxidoreductase [ATP-hydrolysing; peroxiredoxin-(S-hydroxycysteine)-forming]|sulphiredoxin activity				RHEA:17545|MetaCyc:1.8.98.2-RXN|EC:1.8.98.2									molecular_function											owl:Class	
GO:0016209	biolink:NamedThing	antioxidant activity	Inhibition of the reactions brought about by dioxygen (O2) or peroxides. Usually the antioxidant is effective because it can itself be more easily oxidized than the substance protected. The term is often applied to components that can trap free radicals, thereby breaking the chain reaction that normally leads to extensive biological damage.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0089709	biolink:NamedThing	L-histidine transmembrane transport	The directed movement of L-histidine across a membrane.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:2000784	biolink:NamedThing	positive regulation of establishment of cell polarity regulating cell shape	Any process that activates or increases the frequency, rate or extent of establishment of cell polarity regulating cell shape.	tmpzr1t_l9r_go_relaxed.owl								mah	2011-06-23T12:17:48Z					biological_process											owl:Class	
GO:2000782	biolink:NamedThing	regulation of establishment of cell polarity regulating cell shape	Any process that modulates the frequency, rate or extent of establishment of cell polarity regulating cell shape.	tmpzr1t_l9r_go_relaxed.owl								mah	2011-06-23T12:17:38Z					biological_process											owl:Class	
GO:0051127	biolink:NamedThing	positive regulation of actin nucleation	Any process that activates or increases the frequency, rate or extent of actin nucleation, the initial step in the formation of an actin filament in which actin monomers combine to form a new filament.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of actin nucleation|up regulation of actin nucleation|activation of actin nucleation|stimulation of actin nucleation|upregulation of actin nucleation													biological_process											owl:Class	
GO:0051125	biolink:NamedThing	regulation of actin nucleation	Any process that modulates the frequency, rate or extent of actin nucleation, the initial step in the formation of an actin filament in which actin monomers combine to form a new filament.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0004408	biolink:NamedThing	holocytochrome-c synthase activity	Catalysis of the reaction: holocytochrome c = apocytochrome c + heme.	tmpzr1t_l9r_go_relaxed.owl	cytochrome c heme-lyase activity|holocytochrome-c apocytochrome-c-lyase activity|cytochrome c synthase activity|holocytochrome c synthetase activity|holocytochrome-c apocytochrome-c-lyase (heme-forming)				EC:4.4.1.17|MetaCyc:HOLOCYTOCHROME-C-SYNTHASE-RXN|RHEA:22648									molecular_function											owl:Class	
GO:0016846	biolink:NamedThing	carbon-sulfur lyase activity	Catalysis of the elimination of hydrogen sulfide or substituted H2S.	tmpzr1t_l9r_go_relaxed.owl	carbon-sulphur lyase activity				Reactome:R-HSA-1614567|EC:4.4.-.-									molecular_function											owl:Class	
GO:0044211	biolink:NamedThing	CTP salvage	Any process which produces cytidine 5'-triphosphate (CTP) from derivatives of it, without de novo synthesis.	tmpzr1t_l9r_go_relaxed.owl	CTP biosynthetic process via salvage pathway|cytidine 5'-triphosphate salvage							jl	2009-10-22T03:24:04Z					biological_process											owl:Class	
GO:0006241	biolink:NamedThing	CTP biosynthetic process	The chemical reactions and pathways resulting in the formation of CTP, cytidine 5'-triphosphate.	tmpzr1t_l9r_go_relaxed.owl	CTP anabolism|CTP synthesis|CTP biosynthesis|CTP formation													biological_process											owl:Class	
GO:0046016	biolink:NamedThing	positive regulation of transcription by glucose	Any process involving glucose that activates or increases the rate of transcription.	tmpzr1t_l9r_go_relaxed.owl	activation of transcription by glucose|stimulation of transcription by glucose|upregulation of transcription by glucose|up regulation of transcription by glucose|up-regulation of transcription by glucose													biological_process											owl:Class	
GO:0045991	biolink:NamedThing	carbon catabolite activation of transcription	A transcription regulation process in which the presence of one carbon source leads to an increase in the frequency, rate, or extent of transcription of specific genes involved in the metabolism of other carbon sources.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of transcription by carbon catabolites													biological_process											owl:Class	
GO:2000964	biolink:NamedThing	negative regulation of cellooligosaccharide catabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of cellooligosaccharide catabolic process.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of cellooligosaccharide catabolism							tt	2011-08-01T02:28:42Z					biological_process											owl:Class	
GO:2000961	biolink:NamedThing	negative regulation of cellooligosaccharide metabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of cellooligosaccharide metabolic process.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of cellooligosaccharide metabolism							tt	2011-08-01T02:25:59Z					biological_process											owl:Class	
GO:1903125	biolink:NamedThing	negative regulation of thioredoxin peroxidase activity by peptidyl-threonine phosphorylation	A peptidyl-threonine phosphorylation that results in negative regulation of thioredoxin peroxidase activity.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of TrxPx activity by peptidyl-threonine phosphorylation|negative regulation of thiol peroxidase activity by peptidyl-threonine phosphorylation|negative regulation of TPx activity by peptidyl-threonine phosphorylation							bf	2014-06-24T08:47:25Z					biological_process											owl:Class	
GO:0018107	biolink:NamedThing	peptidyl-threonine phosphorylation	The phosphorylation of peptidyl-threonine to form peptidyl-O-phospho-L-threonine.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0038									biological_process											owl:Class	
GO:0061545	biolink:NamedThing	tyramine secretion	The regulated release of a tyramine by a cell.	tmpzr1t_l9r_go_relaxed.owl								dph	2013-06-25T09:14:07Z					biological_process											owl:Class	
GO:0061531	biolink:NamedThing	primary amine secretion	The regulated release of a primary amine by a cell.	tmpzr1t_l9r_go_relaxed.owl								dph	2013-06-21T15:56:08Z					biological_process											owl:Class	
GO:0035707	biolink:NamedThing	T-helper 2 cell chemotaxis	The directed movement of a T-helper 2 cell in response to an external stimulus.	tmpzr1t_l9r_go_relaxed.owl	Th2 cell chemotaxis							bf	2011-03-02T02:37:44Z					biological_process											owl:Class	
GO:0010818	biolink:NamedThing	T cell chemotaxis	The directed movement of a T cell in response to an external stimulus. A T cell is a type of lymphocyte whose defining characteristic is the expression of a T cell receptor complex.	tmpzr1t_l9r_go_relaxed.owl	T-cell chemotaxis													biological_process											owl:Class	
GO:1901192	biolink:NamedThing	positive regulation of formation of translation initiation ternary complex	Any process that activates or increases the frequency, rate or extent of formation of translation initiation ternary complex.	tmpzr1t_l9r_go_relaxed.owl	up regulation of translation initiation ternary complex assembly|activation of formation of translation initiation ternary complex|up regulation of formation of translation initiation ternary complex|up-regulation of translation initiation ternary complex assembly|upregulation of translation initiation ternary complex assembly|up-regulation of formation of translation initiation ternary complex|activation of translation initiation ternary complex assembly|positive regulation of translation initiation ternary complex assembly|upregulation of formation of translation initiation ternary complex							ss	2012-07-25T02:27:29Z					biological_process											owl:Class	
GO:1905752	biolink:NamedThing	regulation of argininosuccinate synthase activity	Any process that modulates the frequency, rate or extent of argininosuccinate synthase activity.	tmpzr1t_l9r_go_relaxed.owl	regulation of argininosuccinic acid synthetase activity|regulation of arginine succinate synthetase activity|regulation of citrulline--aspartate ligase activity|regulation of L-citrulline:L-aspartate ligase (AMP-forming)|regulation of arginosuccinate synthetase activity|regulation of argininosuccinate synthetase activity							dos	2016-12-12T11:43:52Z					biological_process											owl:Class	
GO:0016216	biolink:NamedThing	isopenicillin-N synthase activity	Catalysis of the reaction: N-[(5S)-5-amino-5-carboxypentanoyl]-L-cysteinyl-D-valine + O(2) = 2 H(2)O + isopenicillin N.	tmpzr1t_l9r_go_relaxed.owl	isopenicillin-N synthetase activity|N-[(5S)-5-amino-5-carboxypentanoyl]-L-cysteinyl-D-valine:oxygen oxidoreductase (cyclizing)|isopenicillin N synthase activity				EC:1.21.3.1|RHEA:22428|MetaCyc:1.21.3.1-RXN|KEGG_REACTION:R04872									molecular_function											owl:Class	
GO:0090265	biolink:NamedThing	positive regulation of immune complex clearance by monocytes and macrophages	Any process that increases the rate, frequency, or extent of the process of immune complex clearance by monocytes or macrophages.	tmpzr1t_l9r_go_relaxed.owl								tb	2010-02-04T04:32:18Z					biological_process											owl:Class	
GO:1903921	biolink:NamedThing	regulation of protein processing in phagocytic vesicle	Any process that modulates the frequency, rate or extent of protein processing in phagocytic vesicle.	tmpzr1t_l9r_go_relaxed.owl	regulation of protein maturation by peptide bond cleavage in phagosome|regulation of peptidolysis during protein maturation in phagocytic vesicle|regulation of protein processing in phagosome|regulation of protein maturation by peptide bond hydrolysis in phagosome|regulation of protein maturation by proteolysis in phagosome|regulation of peptidolysis during protein maturation in phagosome|regulation of protein maturation by peptide bond cleavage in phagocytic vesicle|regulation of protein maturation by peptide bond hydrolysis in phagocytic vesicle|regulation of protein maturation by proteolysis in phagocytic vesicle							als	2015-02-10T11:16:54Z					biological_process											owl:Class	
GO:0070613	biolink:NamedThing	regulation of protein processing	Any process that modulates the frequency, rate or extent of protein processing, a protein maturation process achieved by the cleavage of a peptide bond or bonds within a protein.	tmpzr1t_l9r_go_relaxed.owl	regulation of protein maturation by peptide bond cleavage							mah	2009-04-29T02:49:14Z			GO:0010953		biological_process											owl:Class	
GO:0052837	biolink:NamedThing	thiazole biosynthetic process	The chemical reactions and pathways resulting in the formation of a thiazole, a five-membered heterocyclic ring structure containing a sulfur in the 1-position and a nitrogen in the 3-position.	tmpzr1t_l9r_go_relaxed.owl	thiazole anabolism|thiazole synthesis|thiazole biosynthesis|thiazole formation							ai	2011-11-29T03:33:05Z					biological_process											owl:Class	
GO:0032199	biolink:NamedThing	reverse transcription involved in RNA-mediated transposition	The synthesis of DNA from an RNA transposon intermediate.	tmpzr1t_l9r_go_relaxed.owl	reverse transcription during retrotransposition													biological_process											owl:Class	
GO:0001171	biolink:NamedThing	reverse transcription	A DNA synthesis process that uses RNA as the initial template for synthesis of DNA, but which also includes an RNase activity to remove the RNA strand of an RNA-DNA heteroduplex produced by the RNA-dependent synthesis step and use of the initial DNA strand as a template for DNA synthesis.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Reverse_transcription			krc	2011-03-14T03:51:08Z					biological_process											owl:Class	
GO:0071946	biolink:NamedThing	cis-acting DNA replication termination	A DNA replication termination process that is initiated by protein binding to a binding site on the same chromosome, but remote from the termination site, via DNA looping or chromosome kissing.	tmpzr1t_l9r_go_relaxed.owl	cis acting DNA replication termination							mah	2010-10-06T01:08:48Z					biological_process											owl:Class	
GO:1905088	biolink:NamedThing	positive regulation of synaptonemal complex assembly	Any process that activates or increases the frequency, rate or extent of synaptonemal complex assembly.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of synaptonemal complex formation|up regulation of synaptonemal complex formation|up regulation of synaptonemal complex assembly|upregulation of synaptonemal complex formation|activation of synaptonemal complex assembly|up-regulation of synaptonemal complex formation|upregulation of synaptonemal complex assembly|up-regulation of synaptonemal complex assembly|activation of synaptonemal complex formation							mec	2016-03-30T08:39:03Z					biological_process											owl:Class	
GO:0051709	biolink:NamedThing	regulation of killing of cells of other organism	Any process that modulates the frequency, rate or extent of the killing by an organism of cells in another organism.	tmpzr1t_l9r_go_relaxed.owl	modulation of programmed cell death in other organism|modulation of programmed cell death in other organism involved in symbiotic interaction|regulation of killing of cells of another organism|modulation by organism of apoptotic process in other organism involved in symbiotic interaction	https://github.com/geneontology/go-ontology/issues/20287						jl	2012-03-20T04:48:41Z			GO:0044531|GO:0052459|GO:0052248|GO:0052433		biological_process											owl:Class	
GO:0031341	biolink:NamedThing	regulation of cell killing	Any process that modulates the frequency, rate or extent of cell killing, the process in which a cell brings about the death of another cell, either in the same or a different organism.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0015739	biolink:NamedThing	sialic acid transport	The directed movement of sialic acid into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0090170	biolink:NamedThing	regulation of Golgi inheritance	Any process that modulates the rate, frequency or extent of Golgi inheritance. Golgi inheritance is the partitioning of Golgi apparatus between daughter cells at cell division.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-12-11T10:21:59Z					biological_process											owl:Class	
GO:0051176	biolink:NamedThing	positive regulation of sulfur metabolic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving sulfur or compounds containing sulfur.	tmpzr1t_l9r_go_relaxed.owl	up regulation of sulfur metabolic process|positive regulation of sulphur metabolism|upregulation of sulfur metabolic process|positive regulation of sulphur metabolic process|stimulation of sulfur metabolic process|activation of sulfur metabolic process|up-regulation of sulfur metabolic process|positive regulation of sulfur metabolism													biological_process											owl:Class	
GO:0046184	biolink:NamedThing	aldehyde biosynthetic process	The chemical reactions and pathways resulting in the formation of aldehydes, any organic compound with the formula R-CH=O.	tmpzr1t_l9r_go_relaxed.owl	aldehyde biosynthesis|aldehyde synthesis|aldehyde formation|aldehyde anabolism													biological_process											owl:Class	
GO:0098680	biolink:NamedThing	template-free RNA nucleotidyltransferase	Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1); the addition of a terminal nucleotide to an RNA molecule in the absence of a nucleic acid template.	tmpzr1t_l9r_go_relaxed.owl								dos	2017-01-31T15:51:56Z					molecular_function											owl:Class	
GO:2000720	biolink:NamedThing	positive regulation of maintenance of mitotic sister chromatid cohesion, centromeric	Any process that activates or increases the frequency, rate or extent of maintenance of mitotic sister chromatid cohesion in the centromeric region.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of maintenance of centromeric mitotic sister chromatin cohesion|positive regulation of maintenance of mitotic sister chromatin cohesion at centromere|positive regulation of maintenance of sister chromatin cohesion at centromere at mitosis							mah	2011-06-03T10:41:16Z					biological_process											owl:Class	
GO:2000718	biolink:NamedThing	regulation of maintenance of mitotic sister chromatid cohesion, centromeric	Any process that modulates the frequency, rate or extent of maintenance of mitotic sister chromatid cohesion in the centromeric region.	tmpzr1t_l9r_go_relaxed.owl	regulation of maintenance of mitotic sister chromatin cohesion at centromere|regulation of maintenance of centromeric mitotic sister chromatin cohesion|regulation of maintenance of sister chromatin cohesion at centromere at mitosis							mah	2011-06-03T10:41:11Z					biological_process											owl:Class	
GO:0021601	biolink:NamedThing	abducens nerve maturation	A developmental process, independent of morphogenetic (shape) change, that is required for the abducens nerve to attain its fully functional state. The motor function of the abducens nerve is to contract the lateral rectus which results in abduction of the eye.	tmpzr1t_l9r_go_relaxed.owl	CN VI maturation													biological_process											owl:Class	
GO:0021605	biolink:NamedThing	cranial nerve maturation	A developmental process, independent of morphogenetic (shape) change, that is required for a cranial nerve to attain its fully functional state. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0034323	biolink:NamedThing	O-butanoyltransferase activity	Catalysis of the transfer of a butyl group to an oxygen atom on the acceptor molecule.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0034326	biolink:NamedThing	butanoyltransferase activity	Catalysis of the transfer of a butanoyl (CH3-[CH2]2-CO-) group to an acceptor molecule.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0033266	biolink:NamedThing	ABC-type choline transporter activity	Catalysis of the reaction: ATP + H2O = ADP + phosphate, to directly drive the transport of choline across a membrane.	tmpzr1t_l9r_go_relaxed.owl	choline-transporting ATPase activity|ABC-type choline transmembrane transporter activity|ATPase-coupled choline transmembrane transporter activity|ATP-dependent choline transmembrane transporter activity													molecular_function											owl:Class	
GO:0015220	biolink:NamedThing	choline transmembrane transporter activity	Enables the transfer of choline from one side of a membrane to the other. Choline (2-hydroxyethyltrimethylammonium) is an amino alcohol that occurs widely in living organisms as a constituent of certain types of phospholipids and in the neurotransmitter acetylcholine.	tmpzr1t_l9r_go_relaxed.owl	amino acid/choline transmembrane transporter activity|choline permease activity				Reactome:R-HSA-5658483|Reactome:R-HSA-6797956|Reactome:R-HSA-444433|Reactome:R-HSA-429594							GO:0005306		molecular_function											owl:Class	
GO:2000390	biolink:NamedThing	negative regulation of neutrophil extravasation	Any process that stops, prevents or reduces the frequency, rate or extent of neutrophil extravasation.	tmpzr1t_l9r_go_relaxed.owl								mah	2011-02-22T11:08:23Z					biological_process											owl:Class	
GO:0042062	biolink:NamedThing	long-term strengthening of neuromuscular junction	Any process that results in an increase in the efficacy of transmission at a neuromuscular synapse.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0050806	biolink:NamedThing	positive regulation of synaptic transmission	Any process that activates or increases the frequency, rate or extent of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of synaptic transmission|activation of synaptic transmission|stimulation of synaptic transmission|up regulation of synaptic transmission|upregulation of synaptic transmission													biological_process											owl:Class	
GO:1904508	biolink:NamedThing	regulation of protein localization to basolateral plasma membrane	Any process that modulates the frequency, rate or extent of protein localization to basolateral plasma membrane.	tmpzr1t_l9r_go_relaxed.owl	regulation of protein localization in basolateral plasma membrane|regulation of protein localisation to basolateral plasma membrane|regulation of protein localisation in basolateral plasma membrane							kmv	2015-07-24T17:56:26Z					biological_process											owl:Class	
GO:1904375	biolink:NamedThing	regulation of protein localization to cell periphery	Any process that modulates the frequency, rate or extent of protein localization to cell periphery.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-06-22T22:09:25Z					biological_process											owl:Class	
GO:0051257	biolink:NamedThing	meiotic spindle midzone assembly	The formation of the spindle midzone, the area in the center of the spindle where the spindle microtubules from opposite poles overlap, as a part of the process of meiosis.	tmpzr1t_l9r_go_relaxed.owl	spindle midzone biosynthesis involved in meiosis|spindle midzone assembly involved in meiosis|meiotic spindle midzone formation|spindle midzone formation involved in meiosis|meiotic spindle midzone biosynthesis|meiotic spindle midzone biogenesis|spindle midzone biogenesis involved in meiosis													biological_process											owl:Class	
GO:0052707	biolink:NamedThing	N-alpha,N-alpha,N-alpha-trimethyl-L-histidine biosynthesis from histidine	The pathway resulting in the formation of N-alpha,N-alpha,N-alpha-trimethyl-L-histidine from histidine. Histidine undergoes three methylations by a histidine-alpha-N-methyltransferase (EC:2.1.1.44) to form N-alpha,N-alpha,N-alpha-trimethyl-L-histidine (also known as hercynine or histidine betaine).	tmpzr1t_l9r_go_relaxed.owl	hercynine biosynthesis from histidine|histidine catabolism to hercynine|histidine catabolic process to hercynine|histidine betaine biosynthesis from histidine|histidine catabolism to N-alpha,N-alpha,N-alpha-trimethyl-L-histidine				KEGG_REACTION:R01169			ai	2011-08-05T02:07:24Z					biological_process											owl:Class	
GO:0006548	biolink:NamedThing	histidine catabolic process	The chemical reactions and pathways resulting in the breakdown of histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid.	tmpzr1t_l9r_go_relaxed.owl	histidine catabolism|histidine breakdown|histidine degradation													biological_process											owl:Class	
GO:0002193	biolink:NamedThing	MAML1-RBP-Jkappa- ICN1 complex	A protein complex that consists of the intracellular domain of Notch1 (ICN1), the DNA-binding transcription factor RBP-Jkappa, and the transcriptional coactivator Mastermind-like-1 (MAML1); the complex is involved in transcriptional activation in response to Notch-mediated signaling.	tmpzr1t_l9r_go_relaxed.owl	MAML1-RBP-Jkappa-Notch1 complex|MAML1-CSL-Notch1 complex|MAML1-CSL-ICN1							hjd	2011-08-11T04:08:18Z					cellular_component											owl:Class	
GO:0140604	biolink:NamedThing	mycofactocin biosynthetic process	The chemical reactions and pathways resulting in the formation of the coenzyme mycofactocin, a variably glycosylated small molecule electron pair carrier derived from the C-terminal valine-tyrosine dipeptide of the ribosomally translated precursor peptide MftA.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/20547						pg	2021-02-16T07:42:51Z					biological_process											owl:Class	
GO:0033617	biolink:NamedThing	mitochondrial cytochrome c oxidase assembly	The aggregation, arrangement and bonding together of a set of components to form respiratory chain complex IV (also known as cytochrome c oxidase) in the mitochondrial inner membrane.	tmpzr1t_l9r_go_relaxed.owl	mitochondrial cytochrome c oxidase complex assembly|mitochondrial cytochrome c oxidase biogenesis|mitochondrial respiratory chain complex IV assembly													biological_process											owl:Class	
GO:1903522	biolink:NamedThing	regulation of blood circulation	Any process that modulates the frequency, rate or extent of blood circulation.	tmpzr1t_l9r_go_relaxed.owl	regulation of hemolymph circulation							mr	2014-10-06T18:38:56Z					biological_process											owl:Class	
GO:0015700	biolink:NamedThing	arsenite transport	The directed movement of arsenite into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0015698	biolink:NamedThing	inorganic anion transport	The directed movement of inorganic anions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Inorganic anions are atoms or small molecules with a negative charge which do not contain carbon in covalent linkage.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1904114	biolink:NamedThing	positive regulation of muscle filament sliding	Any process that activates or increases the frequency, rate or extent of muscle filament sliding.	tmpzr1t_l9r_go_relaxed.owl	up regulation of muscle filament sliding|activation of muscle filament sliding|up-regulation of muscle filament sliding|upregulation of muscle filament sliding							kmv	2015-04-03T18:40:44Z					biological_process											owl:Class	
GO:1903116	biolink:NamedThing	positive regulation of actin filament-based movement	Any process that activates or increases the frequency, rate or extent of actin filament-based movement.	tmpzr1t_l9r_go_relaxed.owl	activation of actin filament-based movement|upregulation of actin filament-based movement|up regulation of actin filament-based movement|up-regulation of actin filament-based movement							al	2014-06-12T16:56:04Z					biological_process											owl:Class	
GO:0018258	biolink:NamedThing	protein O-linked glycosylation via hydroxyproline	The glycosylation of proteins via 04 atom of hydroxyproline to form O4-glycosyl-L-hydroxyproline; the most common form is arabinofuranosyl-4-proline.	tmpzr1t_l9r_go_relaxed.owl	protein amino acid O-linked glycosylation via hydroxyproline				RESID:AA0212									biological_process											owl:Class	
GO:0018208	biolink:NamedThing	peptidyl-proline modification	The modification of peptidyl-proline.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0090341	biolink:NamedThing	negative regulation of secretion of lysosomal enzymes	Any process that decreases the rate, frequency or extent of secretion of lysosomal enzymes, the controlled release of lysosomal enzymes by a cell.	tmpzr1t_l9r_go_relaxed.owl								tb	2010-06-01T03:35:57Z					biological_process											owl:Class	
GO:0050709	biolink:NamedThing	negative regulation of protein secretion	Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of a protein from a cell.	tmpzr1t_l9r_go_relaxed.owl	downregulation of protein secretion|down regulation of protein secretion|inhibition of protein secretion|down-regulation of protein secretion													biological_process											owl:Class	
GO:1905564	biolink:NamedThing	positive regulation of vascular endothelial cell proliferation	Any process that activates or increases the frequency, rate or extent of vascular endothelial cell proliferation.	tmpzr1t_l9r_go_relaxed.owl	activation of vascular endothelial cell proliferation|up regulation of vascular endothelial cell proliferation|up-regulation of vascular endothelial cell proliferation|upregulation of vascular endothelial cell proliferation							nc	2016-10-17T09:24:35Z					biological_process											owl:Class	
GO:1905562	biolink:NamedThing	regulation of vascular endothelial cell proliferation	Any process that modulates the frequency, rate or extent of vascular endothelial cell proliferation.	tmpzr1t_l9r_go_relaxed.owl								nc	2016-10-17T09:24:17Z					biological_process											owl:Class	
GO:0099088	biolink:NamedThing	axonal transport of messenger ribonucleoprotein complex	The directed movement of a messenger ribonucleoprotein complex along microtubules in axons.	tmpzr1t_l9r_go_relaxed.owl	axonal transport of mRNA RNP complex													biological_process											owl:Class	
GO:0001765	biolink:NamedThing	membrane raft assembly	The aggregation, arrangement and bonding together of a set of components to form a membrane raft, a small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalizes cellular processes.	tmpzr1t_l9r_go_relaxed.owl	membrane raft formation|lipid raft formation|lipid raft assembly													biological_process											owl:Class	
GO:0031579	biolink:NamedThing	membrane raft organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of membrane rafts, small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes.	tmpzr1t_l9r_go_relaxed.owl	lipid raft organization|membrane raft organisation|membrane raft organization and biogenesis													biological_process											owl:Class	
GO:0050924	biolink:NamedThing	positive regulation of negative chemotaxis	Any process that activates or increases the frequency, rate or extent of the directed movement of a motile cell or organism towards a lower concentration in a concentration gradient of a specific chemical.	tmpzr1t_l9r_go_relaxed.owl	stimulation of negative chemotaxis|up-regulation of negative chemotaxis|up regulation of negative chemotaxis|upregulation of negative chemotaxis|activation of negative chemotaxis													biological_process											owl:Class	
GO:0015144	biolink:NamedThing	carbohydrate transmembrane transporter activity	Enables the transfer of carbohydrate from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	sugar transporter|carbohydrate transporter activity											GO:1901476		molecular_function											owl:Class	
GO:0018762	biolink:NamedThing	aliphatic nitrilase activity	Catalysis of the reaction: R-CN + H2O = R-COOH + NH3.	tmpzr1t_l9r_go_relaxed.owl	aliphatic nitrile aminohydrolase activity				UM-BBD_reactionID:r0622|EC:3.5.5.7|RHEA:46188|MetaCyc:3.5.5.7-RXN									molecular_function											owl:Class	
GO:1902208	biolink:NamedThing	regulation of bacterial-type flagellum assembly	Any process that modulates the frequency, rate or extent of bacterial-type flagellum assembly.	tmpzr1t_l9r_go_relaxed.owl	regulation of bacterial flagellum assembly							jl	2013-06-11T14:20:19Z					biological_process											owl:Class	
GO:0033438	biolink:NamedThing	ACC codon-amino acid adaptor activity	A triplet codon-amino acid adaptor activity that recognizes an ACC codon.	tmpzr1t_l9r_go_relaxed.owl	threonine tRNA					Note that in the standard genetic code, ACC codes for threonine.								molecular_function											owl:Class	
GO:0006524	biolink:NamedThing	alanine catabolic process	The chemical reactions and pathways resulting in the breakdown of alanine, 2-aminopropanoic acid.	tmpzr1t_l9r_go_relaxed.owl	alanine breakdown|alanine degradation|alanine catabolism													biological_process											owl:Class	
GO:0120290	biolink:NamedThing	stalled replication fork localization to nuclear periphery	A cellular localization process where a DNA replication fork that has stalled is signaled to relocate and anchor to the nuclear periphery for the time necessary to complete recombination-dependent replication.	tmpzr1t_l9r_go_relaxed.owl	stalled replication fork localization to nuclear periphery involved in replication fork processing	https://github.com/geneontology/go-ontology/issues/20443						krc	2020-11-23T20:25:43Z					biological_process											owl:Class	
GO:0021611	biolink:NamedThing	facial nerve formation	The process that gives rise to the facial nerve. This process pertains to the initial formation of a structure from unspecified parts. This sensory and motor nerve supplies the muscles of facial expression and the expression and taste at the anterior two-thirds of the tongue. The principal branches are the superficial opthalmic, buccal, palatine and hyomandibular. The main trunk synapses within pterygopalatine ganglion in the parotid gland and this ganglion then gives of nerve branches which supply the lacrimal gland and the mucous secreting glands of the nasal and oral cavities.	tmpzr1t_l9r_go_relaxed.owl	CN VII formation|CN VII biosynthesis													biological_process											owl:Class	
GO:0021603	biolink:NamedThing	cranial nerve formation	The process that gives rise to the cranial nerves. This process pertains to the initial formation of a structure from unspecified parts. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0071792	biolink:NamedThing	bacillithiol metabolic process	The chemical reactions and pathways involving bacillithiol, the alpha-anomeric glycoside of L-cysteinyl-D-glucosamine with L-malic acid. Bacillithiol, produced widely in the Firmicutes and sporadically in other bacterial lineages, is a low-molecular-weight thiol analogous to mycothiol in the Actinomycetes and glutathione in many species.	tmpzr1t_l9r_go_relaxed.owl	bacillithiol metabolism							mah	2010-09-02T11:13:47Z					biological_process											owl:Class	
GO:0046228	biolink:NamedThing	2,4,5-trichlorophenoxyacetic acid catabolic process	The chemical reactions and pathways resulting in the breakdown of 2,4,5-trichlorophenoxyacetic acid, a chlorinated aromatic compound widely used as a herbicide.	tmpzr1t_l9r_go_relaxed.owl	2,4,5-trichlorophenoxyacetic acid degradation|2,4,5-trichlorophenoxyacetic acid catabolism|2,4,5-trichlorophenoxyacetic acid breakdown													biological_process											owl:Class	
GO:0018980	biolink:NamedThing	2,4,5-trichlorophenoxyacetic acid metabolic process	The chemical reactions and pathways involving 2,4,5-trichlorophenoxyacetic acid, a chlorinated aromatic compound which is widely used as a herbicide, often as a weed killer for home lawns.	tmpzr1t_l9r_go_relaxed.owl	2,4,5-T metabolic process|2,4,5-trichlorophenoxyacetic acid metabolism|2,4,5-T metabolism				UM-BBD_pathwayID:2,4,5-t									biological_process											owl:Class	
GO:1903327	biolink:NamedThing	negative regulation of tRNA metabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of tRNA metabolic process.	tmpzr1t_l9r_go_relaxed.owl	inhibition of tRNA metabolism|downregulation of tRNA metabolic process|negative regulation of tRNA metabolism|inhibition of tRNA metabolic process|down regulation of tRNA metabolic process|down-regulation of tRNA metabolic process|downregulation of tRNA metabolism|down regulation of tRNA metabolism|down-regulation of tRNA metabolism							vw	2014-08-18T13:08:58Z					biological_process											owl:Class	
GO:0046286	biolink:NamedThing	flavonoid phytoalexin catabolic process	The chemical reactions and pathways resulting in the breakdown of flavonoid phytoalexins, a group of water-soluble phenolic derivatives containing a flavan skeleton, which possess antibiotic activity and are produced by plant tissues in response to infection.	tmpzr1t_l9r_go_relaxed.owl	flavonoid phytoalexin breakdown|flavonoid phytoalexin catabolism|flavonoid phytoalexin degradation													biological_process											owl:Class	
GO:0046275	biolink:NamedThing	flavonoid catabolic process	The chemical reactions and pathways resulting in the breakdown of flavonoids, a group of phenolic derivatives containing a flavan skeleton.	tmpzr1t_l9r_go_relaxed.owl	flavonoid catabolism|flavonoid degradation|flavonoid breakdown													biological_process											owl:Class	
GO:0015031	biolink:NamedThing	protein transport	The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	enzyme transport											GO:0015831		biological_process											owl:Class	
GO:0042878	biolink:NamedThing	D-glucarate transmembrane transporter activity	Enables the transfer of D-glucarate, the D-enantiomer of glucarate, from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0005310	biolink:NamedThing	dicarboxylic acid transmembrane transporter activity	Enables the transfer of dicarboxylic acids from one side of a membrane to the other. A dicarboxylic acid is an organic acid with two COOH groups.	tmpzr1t_l9r_go_relaxed.owl	dicarboxylic acid permease activity|dicarboxylate carrier|dicarboxylate (succinate/fumarate/malate) antiporter activity|sodium:dicarboxylate/tricarboxylate symporter activity				Reactome:R-HSA-372843|Reactome:R-HSA-1614546							GO:0005312|GO:0015365		molecular_function											owl:Class	
GO:0051871	biolink:NamedThing	dihydrofolic acid binding	Binding to dihydrofolic acid, a folic acid in which the bicyclic pteridine structure is in the dihydro, partially reduced form; they are intermediates in folate metabolism and are reduced to their tetrahydro, reduced forms.	tmpzr1t_l9r_go_relaxed.owl	dihydrofolate binding|DHF binding													molecular_function											owl:Class	
GO:1901363	biolink:NamedThing	heterocyclic compound binding	Binding to heterocyclic compound.	tmpzr1t_l9r_go_relaxed.owl								bf	2012-09-14T13:53:50Z					molecular_function											owl:Class	
GO:1905577	biolink:NamedThing	ganglioside GP1c binding	Binding to ganglioside GP1c.	tmpzr1t_l9r_go_relaxed.owl								pga	2016-10-19T11:17:25Z					molecular_function											owl:Class	
GO:0035594	biolink:NamedThing	ganglioside binding	Binding to a ganglioside, a ceramide oligosaccharide carrying in addition to other sugar residues, one or more sialic acid residues.	tmpzr1t_l9r_go_relaxed.owl								bf	2010-11-11T02:11:38Z					molecular_function											owl:Class	
GO:1905148	biolink:NamedThing	negative regulation of smooth muscle hypertrophy	Any process that stops, prevents or reduces the frequency, rate or extent of smooth muscle hypertrophy.	tmpzr1t_l9r_go_relaxed.owl	down regulation of smooth muscle hypertrophy|inhibition of smooth muscle hypertrophy|downregulation of smooth muscle hypertrophy|down-regulation of smooth muscle hypertrophy							bc	2016-04-15T12:47:16Z					biological_process											owl:Class	
GO:0014745	biolink:NamedThing	negative regulation of muscle adaptation	Any process that stops, prevents, or reduces the frequency, rate, or extent of muscle adaptation.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of muscle plasticity													biological_process											owl:Class	
GO:0004813	biolink:NamedThing	alanine-tRNA ligase activity	Catalysis of the reaction: ATP + L-alanine + tRNA(Ala) = AMP + diphosphate + L-alanyl-tRNA(Ala).	tmpzr1t_l9r_go_relaxed.owl	alanine-transfer RNA ligase activity|AlaRS|alanine tRNA synthetase activity|alanyl-transfer ribonucleic acid synthetase activity|alanyl-tRNA synthetase activity|alanyl-transfer ribonucleate synthetase activity|alanyl-transfer RNA synthetase activity|Ala-tRNA synthetase activity|alanine translase activity|alanine transfer RNA synthetase activity|L-alanine:tRNAAla ligase (AMP-forming)|alanyl-transfer ribonucleate synthase activity				Reactome:R-HSA-380177|MetaCyc:ALANINE--TRNA-LIGASE-RXN|RHEA:12540|Reactome:R-HSA-379864|EC:6.1.1.7									molecular_function											owl:Class	
GO:1902511	biolink:NamedThing	negative regulation of apoptotic DNA fragmentation	Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic DNA fragmentation.	tmpzr1t_l9r_go_relaxed.owl	inhibition of DNA fragmentation involved in apoptotic nuclear change|downregulation of DNA catabolism during apoptosis|inhibition of DNA catabolism during apoptosis|negative regulation of endonucleolytic DNA catabolic process involved in apoptosis|down regulation of apoptotic DNA fragmentation|negative regulation of DNA fragmentation involved in apoptotic nuclear change|inhibition of apoptotic DNA fragmentation|down regulation of DNA catabolism during apoptosis|down-regulation of DNA catabolism during apoptosis|down-regulation of DNA catabolic process during apoptosis|down regulation of endonucleolytic DNA catabolic process involved in apoptosis|inhibition of DNA catabolic process during apoptosis|downregulation of DNA fragmentation involved in apoptotic nuclear change|downregulation of DNA catabolic process during apoptosis|down regulation of DNA fragmentation involved in apoptotic nuclear change|inhibition of endonucleolytic DNA catabolic process involved in apoptosis|down-regulation of endonucleolytic DNA catabolic process involved in apoptosis|downregulation of endonucleolytic DNA catabolic process involved in apoptosis|down regulation of DNA catabolic process during apoptosis|negative regulation of DNA catabolism during apoptosis|downregulation of apoptotic DNA fragmentation|down-regulation of apoptotic DNA fragmentation|negative regulation of DNA catabolic process during apoptosis|down-regulation of DNA fragmentation involved in apoptotic nuclear change							hjd	2013-11-15T18:28:41Z					biological_process											owl:Class	
GO:1902344	biolink:NamedThing	negative regulation of maltose transport	Any process that stops, prevents or reduces the frequency, rate or extent of maltose transport.	tmpzr1t_l9r_go_relaxed.owl	inhibition of maltose transport|downregulation of maltose transport|down regulation of maltose transport|down-regulation of maltose transport							dph	2013-08-01T17:16:26Z					biological_process											owl:Class	
GO:0097590	biolink:NamedThing	archaeal-type flagellum-dependent cell motility	Cell motility due to the motion of one or more archaeal-type flagella. An archaeal-type flagellum (also called archaellum) is a non-membrane-bounded organelle superficially similar to a bacterial-type flagellum, but having a different molecular structure and lacking a central channel.	tmpzr1t_l9r_go_relaxed.owl	archaeal-type flagellar cell motility							pr	2014-03-25T20:40:50Z					biological_process											owl:Class	
GO:0097588	biolink:NamedThing	archaeal or bacterial-type flagellum-dependent cell motility	Cell motility due to movement of bacterial- or archaeal-type flagella.	tmpzr1t_l9r_go_relaxed.owl						Bacterial- and archaeal-type flagella are superficially similar but have a different molecular composition and fine structure. This term was added for mapping to the UniProt keyword "flagellar rotation". For manual annotation, please use one of the child terms of GO:0097588 that refer specifically to either archaeal- or bacterial-type flagella.		pr	2014-03-25T16:51:19Z					biological_process											owl:Class	
GO:2000552	biolink:NamedThing	negative regulation of T-helper 2 cell cytokine production	Any process that stops, prevents or reduces the frequency, rate or extent of T-helper 2 cell cytokine production.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of Th2 cell cytokine production							ebc	2011-04-03T07:32:54Z					biological_process											owl:Class	
GO:1903941	biolink:NamedThing	negative regulation of respiratory gaseous exchange	Any process that stops, prevents or reduces the frequency, rate or extent of respiratory gaseous exchange.	tmpzr1t_l9r_go_relaxed.owl	down regulation of respiratory gaseous exchange|down-regulation of respiratory gaseous exchange|inhibition of respiratory gaseous exchange|downregulation of respiratory gaseous exchange							sl	2015-02-17T20:26:24Z					biological_process											owl:Class	
GO:2000669	biolink:NamedThing	negative regulation of dendritic cell apoptotic process	Any process that stops, prevents or reduces the frequency, rate or extent of dendritic cell apoptotic process.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of dendritic cell apoptosis							pr	2011-05-09T07:34:21Z					biological_process											owl:Class	
GO:1905278	biolink:NamedThing	positive regulation of epithelial tube formation	Any process that activates or increases the frequency, rate or extent of epithelial tube formation.	tmpzr1t_l9r_go_relaxed.owl	up regulation of epithelial tube formation|activation of epithelial tube formation|up-regulation of epithelial tube formation|upregulation of epithelial tube formation					An example of this is MMRN2 in human (Q9H8L6) in PMID:25745997 (inferred from direct assay).		bhm	2016-06-20T09:35:57Z					biological_process											owl:Class	
GO:0004966	biolink:NamedThing	galanin receptor activity	Combining with galanin to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0008188	biolink:NamedThing	neuropeptide receptor activity	Combining with a neuropeptide to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0018880	biolink:NamedThing	4-chlorobiphenyl metabolic process	The chemical reactions and pathways involving 4-chlorobiphenyl, a member of the polychlorinated biphenyl (PCB) group of compounds, a very stable group of synthetic organic compounds composed of a biphenyl nucleus with 1-10 chlorine substituents. 4-chlorobiphenyl has been used as a model substrate to investigate PCB degradation.	tmpzr1t_l9r_go_relaxed.owl	4-chlorobiphenyl metabolism				UM-BBD_pathwayID:cbp									biological_process											owl:Class	
GO:0042196	biolink:NamedThing	chlorinated hydrocarbon metabolic process	The chemical reactions and pathways involving chlorinated hydrocarbons, compounds derived from hydrocarbons by replacing one or more hydrogen atoms with chlorine atoms.	tmpzr1t_l9r_go_relaxed.owl	chlorinated hydrocarbon metabolism													biological_process											owl:Class	
GO:0097636	biolink:NamedThing	intrinsic component of autophagosome membrane	The component of the autophagosome membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.	tmpzr1t_l9r_go_relaxed.owl	intrinsic component of autophagic vacuole membrane|intrinsic to autophagic vacuole membrane													cellular_component											owl:Class	
GO:0061413	biolink:NamedThing	regulation of transcription from RNA polymerase II promoter by a nonfermentable carbon source	A transcription regulation process in which the presence of a nonfermentable carbon source leads to the modulation of the frequency, rate, or extent of transcription, from an RNA polymerase II promoter, of specific genes involved in the metabolism of other carbon sources.	tmpzr1t_l9r_go_relaxed.owl								dph	2012-01-23T11:13:06Z					biological_process											owl:Class	
GO:0031314	biolink:NamedThing	extrinsic component of mitochondrial inner membrane	The component of mitochondrial inner membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.	tmpzr1t_l9r_go_relaxed.owl	extrinsic to mitochondrial inner membrane													cellular_component											owl:Class	
GO:0031312	biolink:NamedThing	extrinsic component of organelle membrane	The component of an organelle membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.	tmpzr1t_l9r_go_relaxed.owl	extrinsic to organelle membrane													cellular_component											owl:Class	
GO:0034406	biolink:NamedThing	cell wall beta-glucan metabolic process	The chemical reactions and pathways involving beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds, found in the walls of cells.	tmpzr1t_l9r_go_relaxed.owl	cell wall beta-glucan metabolism													biological_process											owl:Class	
GO:0002615	biolink:NamedThing	positive regulation of monocyte antigen processing and presentation	Any process that activates or increases the frequency, rate, or extent of monocyte antigen processing and presentation.	tmpzr1t_l9r_go_relaxed.owl	upregulation of monocyte antigen processing and presentation|up regulation of monocyte antigen processing and presentation|stimulation of monocyte antigen processing and presentation|activation of monocyte antigen processing and presentation|up-regulation of monocyte antigen processing and presentation													biological_process											owl:Class	
GO:0002613	biolink:NamedThing	regulation of monocyte antigen processing and presentation	Any process that modulates the frequency, rate, or extent of monocyte antigen processing and presentation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0043620	biolink:NamedThing	regulation of DNA-templated transcription in response to stress	Modulation of the frequency, rate or extent of transcription from a DNA template as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).	tmpzr1t_l9r_go_relaxed.owl	regulation of DNA-dependent transcription in response to stress													biological_process											owl:Class	
GO:0042189	biolink:NamedThing	vanillin biosynthetic process	The chemical reactions and pathways resulting in the formation of vanillin, an aromatic hydrocarbon which occurs naturally in black vanilla bean pods.	tmpzr1t_l9r_go_relaxed.owl	vanillin synthesis|vanillic aldehyde biosynthesis|vanillic aldehyde biosynthetic process|vanillin anabolism|vanillin formation|vanillin biosynthesis													biological_process											owl:Class	
GO:0018982	biolink:NamedThing	vanillin metabolic process	The chemical reactions and pathways involving vanillin, an aromatic hydrocarbon which occurs naturally in black vanilla bean pods and can be obtained as a by-product of the pulp and paper industry by the oxidative breakdown of lignin.	tmpzr1t_l9r_go_relaxed.owl	vanillic aldehyde metabolic process|vanillic aldehyde metabolism|vanillin metabolism				UM-BBD_pathwayID:van									biological_process											owl:Class	
GO:1904407	biolink:NamedThing	positive regulation of nitric oxide metabolic process	Any process that activates or increases the frequency, rate or extent of nitric oxide metabolic process.	tmpzr1t_l9r_go_relaxed.owl	activation of nitric oxide metabolic process|upregulation of nitric oxide metabolic process|up regulation of nitric oxide metabolism|up-regulation of nitric oxide metabolic process|upregulation of nitric oxide metabolism|positive regulation of nitric oxide metabolism|up regulation of nitric oxide metabolic process|up-regulation of nitric oxide metabolism|activation of nitric oxide metabolism							sl	2015-06-24T20:56:47Z					biological_process											owl:Class	
GO:0110067	biolink:NamedThing	ammonium transmembrane transporter complex	High affinity ammonium transporter complex that enables the transfer of ammonium from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	AMT1 complex							kmv	2017-11-20T15:21:10Z					cellular_component											owl:Class	
GO:1902495	biolink:NamedThing	transmembrane transporter complex	A transmembrane protein complex which enables the transfer of a substance from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl								bhm	2013-11-13T16:23:04Z					cellular_component											owl:Class	
GO:0002256	biolink:NamedThing	regulation of kinin cascade	Any process that modulates the frequency, rate, or extent of the kinin cascade.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0002673	biolink:NamedThing	regulation of acute inflammatory response	Any process that modulates the frequency, rate, or extent of an acute inflammatory response.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0042130	biolink:NamedThing	negative regulation of T cell proliferation	Any process that stops, prevents or reduces the rate or extent of T cell proliferation.	tmpzr1t_l9r_go_relaxed.owl	inhibition of T cell proliferation|negative regulation of T lymphocyte proliferation|negative regulation of T-lymphocyte proliferation|downregulation of T cell proliferation|down-regulation of T cell proliferation|down regulation of T cell proliferation|negative regulation of T-cell proliferation													biological_process											owl:Class	
GO:0050672	biolink:NamedThing	negative regulation of lymphocyte proliferation	Any process that stops, prevents or reduces the rate or extent of lymphocyte proliferation.	tmpzr1t_l9r_go_relaxed.owl	downregulation of lymphocyte proliferation|inhibition of lymphocyte proliferation|down-regulation of lymphocyte proliferation|down regulation of lymphocyte proliferation													biological_process											owl:Class	
GO:0042367	biolink:NamedThing	biotin catabolic process	The chemical reactions and pathways resulting in the breakdown of biotin, cis-tetrahydro-2-oxothieno(3,4-d)imidazoline-4-valeric acid.	tmpzr1t_l9r_go_relaxed.owl	vitamin B7 catabolic process|vitamin H catabolic process|biotin breakdown|biotin catabolism|vitamin B7 catabolism|biotin degradation|vitamin H catabolism													biological_process											owl:Class	
GO:0003046	biolink:NamedThing	regulation of systemic arterial blood pressure by stress relaxation	The intrinsic circulatory process resulting from stress relaxation that modulates the force with which blood travels through the systemic arterial circulatory system. Stress relaxation is the adaptation of vessels to a new size as a result of changes in pressure in storage areas such as veins, the liver, the spleen, and the lungs.	tmpzr1t_l9r_go_relaxed.owl	blood pressure regulation by stress relaxation													biological_process											owl:Class	
GO:0003085	biolink:NamedThing	negative regulation of systemic arterial blood pressure	The process that reduces the force with which blood travels through the systemic arterial circulatory system.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0010757	biolink:NamedThing	negative regulation of plasminogen activation	Any process that decreases the rate, frequency or extent of plasminogen activation. Plasminogen activation is the process in which plasminogen is processed to plasmin.	tmpzr1t_l9r_go_relaxed.owl	inhibition of plasminogen activation													biological_process											owl:Class	
GO:0061541	biolink:NamedThing	rhabdomere morphogenesis	The process in which the anatomical structures of a rhabdomere are generated and organized. The rhabdomere is the organelle on the apical surface of a photoreceptor cell that contains the visual pigments.	tmpzr1t_l9r_go_relaxed.owl								dph	2013-06-24T07:59:25Z					biological_process											owl:Class	
GO:0048812	biolink:NamedThing	neuron projection morphogenesis	The process in which the anatomical structures of a neuron projection are generated and organized. A neuron projection is any process extending from a neural cell, such as axons or dendrites.	tmpzr1t_l9r_go_relaxed.owl	neurite formation|neurite growth|neurite biosynthesis|neurite morphogenesis													biological_process											owl:Class	
GO:0002408	biolink:NamedThing	myeloid dendritic cell chemotaxis	The movement of a myeloid dendritic cell in response to an external stimulus.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0097529	biolink:NamedThing	myeloid leukocyte migration	The movement of a myeloid leukocyte within or between different tissues and organs of the body.	tmpzr1t_l9r_go_relaxed.owl								pr	2013-11-11T13:59:43Z					biological_process											owl:Class	
GO:1905439	biolink:NamedThing	response to chondroitin 6'-sulfate	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chondroitin 6'-sulfate stimulus.	tmpzr1t_l9r_go_relaxed.owl								cvs	2016-09-14T18:56:12Z					biological_process											owl:Class	
GO:0031440	biolink:NamedThing	regulation of mRNA 3'-end processing	Any process that modulates the frequency, rate or extent of mRNA 3'-end processing, any process involved in forming the mature 3' end of an mRNA molecule.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0061402	biolink:NamedThing	positive regulation of transcription from RNA polymerase II promoter in response to acidic pH	Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a pH stimulus with pH < 7.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of transcription from RNA polymerase II promoter in response to acidity							dph	2012-01-10T03:06:32Z					biological_process											owl:Class	
GO:0060632	biolink:NamedThing	regulation of microtubule-based movement	Any process that modulates the rate, frequency, or extent of microtubule-based movement, the movement of organelles, other microtubules and other particles along microtubules, mediated by motor proteins.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-05-18T03:07:02Z					biological_process											owl:Class	
GO:0022809	biolink:NamedThing	mobile ion carrier activity	Small molecule produced by bacteria that carries an ion across the membrane by enclosing the ion and travelling with the ion across the membrane. It does not form a fully open pore across the membrane.	tmpzr1t_l9r_go_relaxed.owl	ionophore													molecular_function											owl:Class	
GO:0022857	biolink:NamedThing	transmembrane transporter activity	Enables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	uptake permease activity|substrate-specific transporter activity|substrate-specific transmembrane transporter activity|uptake transmembrane transporter activity				Reactome:R-HSA-1236947|Reactome:R-HSA-6784434|Reactome:R-HSA-5638209|Reactome:R-HSA-429036|Reactome:R-HSA-5671707|Reactome:R-HSA-6784436							GO:0015646|GO:0022892|GO:0005386|GO:0022891|GO:0015563		molecular_function											owl:Class	
GO:0009073	biolink:NamedThing	aromatic amino acid family biosynthetic process	The chemical reactions and pathways resulting in the formation of aromatic amino acid family, amino acids with aromatic ring (phenylalanine, tyrosine, tryptophan).	tmpzr1t_l9r_go_relaxed.owl	aromatic amino acid family biosynthetic process, shikimate pathway|aromatic amino acid family biosynthesis|aromatic amino acid family formation|aromatic amino acid family anabolism|aromatic amino acid family synthesis				MetaCyc:COMPLETE-ARO-PWY							GO:0016089		biological_process											owl:Class	
GO:0014861	biolink:NamedThing	regulation of skeletal muscle contraction via regulation of action potential	Any process that modulates the frequency, rate or extent of skeletal muscle contraction by depolarization of muscle membrane and ionic fluxes.	tmpzr1t_l9r_go_relaxed.owl	regulation of skeletal muscle contraction via membrane action potential													biological_process											owl:Class	
GO:0006956	biolink:NamedThing	complement activation	Any process involved in the activation of any of the steps of the complement cascade, which allows for the direct killing of microbes, the disposal of immune complexes, and the regulation of other immune processes; the initial steps of complement activation involve one of three pathways, the classical pathway, the alternative pathway, and the lectin pathway, all of which lead to the terminal complement pathway.	tmpzr1t_l9r_go_relaxed.owl	complement cascade|complement activity|complement response													biological_process											owl:Class	
GO:0002253	biolink:NamedThing	activation of immune response	Any process that initiates an immune response.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1901282	biolink:NamedThing	fructoselysine biosynthetic process	The chemical reactions and pathways resulting in the formation of fructoselysine.	tmpzr1t_l9r_go_relaxed.owl	fructosyllysine biosynthesis|fructosyllysine formation|fructosyllysine synthesis|fructosyllysine biosynthetic process|fructosyllysine anabolism							yaf	2012-08-17T15:05:05Z					biological_process											owl:Class	
GO:0070957	biolink:NamedThing	negative regulation of neutrophil mediated killing of gram-negative bacterium	Any process that decreases the frequency, rate or extent of the directed killing of a gram-negative bacterium by a neutrophil.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of neutrophil mediated killing of gram-negative bacterium|down regulation of neutrophil mediated killing of gram-negative bacterium|inhibition of neutrophil mediated killing of gram-negative bacterium|downregulation of neutrophil mediated killing of gram-negative bacterium							mah	2009-10-01T02:20:17Z					biological_process											owl:Class	
GO:0070951	biolink:NamedThing	regulation of neutrophil mediated killing of gram-negative bacterium	Any process that modulates the rate, frequency or extent of neutrophil mediated killing of a gram-negative bacterium, the directed killing of a gram-negative bacterium by a neutrophil.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-10-01T02:14:36Z					biological_process											owl:Class	
GO:0010683	biolink:NamedThing	tricyclic triterpenoid metabolic process	The chemical reactions and pathways involving tricyclic triterpenoid compounds, terpenoids with six isoprene units and 3 rings.	tmpzr1t_l9r_go_relaxed.owl	tricyclic triterpenoid metabolism													biological_process											owl:Class	
GO:0004131	biolink:NamedThing	cytosine deaminase activity	Catalysis of the reaction: cytosine + H2O = uracil + NH3.	tmpzr1t_l9r_go_relaxed.owl	isocytosine deaminase activity|cytosine aminohydrolase activity				RHEA:20605|EC:3.5.4.1|MetaCyc:CYTDEAM-RXN									molecular_function											owl:Class	
GO:0016814	biolink:NamedThing	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a cyclic amidine, a compound of the form R-C(=NH)-NH2.	tmpzr1t_l9r_go_relaxed.owl					EC:3.5.4.-									molecular_function											owl:Class	
GO:0032874	biolink:NamedThing	positive regulation of stress-activated MAPK cascade	Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the stress-activated MAPK cascade.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of stress-activated MAPKKK signalling pathway|positive regulation of stress-activated MAPK signaling pathway|positive regulation of p38 MAPK signalling|up-regulation of stress-activated MAPK cascade|positive regulation of stress-activated MAPKKK cascade|positive regulation of stress-activated MAPK signalling pathway|up regulation of stress-activated MAPK cascade|positive regulation of p38 MAPK signaling|upregulation of stress-activated MAPK cascade|activation of stress-activated MAPK cascade|stimulation of stress-activated MAPK cascade|positive regulation of stress-activated MAPKKK signaling pathway													biological_process											owl:Class	
GO:0060716	biolink:NamedThing	labyrinthine layer blood vessel development	The process whose specific outcome is the progression of a blood vessel of the labyrinthine layer of the placenta over time, from its formation to the mature structure. The embryonic vessels grow through the layer to come in close contact with the maternal blood supply.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-06-11T09:04:38Z					biological_process											owl:Class	
GO:0048608	biolink:NamedThing	reproductive structure development	The reproductive developmental process whose specific outcome is the progression of somatic structures that will be used in the process of creating new individuals from one or more parents, from their formation to the mature structures.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1990573	biolink:NamedThing	potassium ion import across plasma membrane	The directed movement of potassium ions from outside of a cell, across the plasma membrane and into the cytosol.	tmpzr1t_l9r_go_relaxed.owl	potassium ion import|potassium ion uptake|potassium import							vw	2014-12-04T09:48:12Z			GO:0010107		biological_process											owl:Class	
GO:0098659	biolink:NamedThing	inorganic cation import across plasma membrane	The directed movement of inorganic cations from outside of a cell, across the plasma membrane and into the cytosol.	tmpzr1t_l9r_go_relaxed.owl	inorganic cation import into cell													biological_process											owl:Class	
GO:0098571	biolink:NamedThing	lumenal side of plastid thylakoid membrane	The side (leaflet) of the plastid thylakoid membrane that faces the lumen, and any proteins embedded in it or loosely bound to its surface.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0098552	biolink:NamedThing	side of membrane	A cellular component consisting of one leaflet of a membrane bilayer and any proteins embedded or anchored in it or attached to its surface.	tmpzr1t_l9r_go_relaxed.owl								dos	2013-12-03T11:28:04Z					cellular_component											owl:Class	
GO:0005655	biolink:NamedThing	nucleolar ribonuclease P complex	A ribonuclease P complex located in the nucleolus of a eukaryotic cell, where it catalyzes the 5' endonucleolytic cleavage of precursor tRNAs to yield mature tRNAs. Eukaryotic nucleolar ribonuclease P complexes generally contain a single RNA molecule that is necessary but not sufficient for catalysis, and several protein molecules.	tmpzr1t_l9r_go_relaxed.owl	nucleolar RNase P complex													cellular_component											owl:Class	
GO:0030681	biolink:NamedThing	multimeric ribonuclease P complex	A ribonuclease P complex that generally contains a single RNA molecule and several protein molecules. Examples of this complex are found in Archaeal species.	tmpzr1t_l9r_go_relaxed.owl	multimeric RNase P complex													cellular_component											owl:Class	
GO:0103054	biolink:NamedThing	gibberellin A12, 2-oxoglutarate:oxygen oxidoreductase activity (gibberellin A15-forming)	Catalysis of the reaction: gibberellin A12 + O2 + 2-oxoglutarate <=> gibberellin A15 + carbon dioxide + succinate.	tmpzr1t_l9r_go_relaxed.owl					RHEA:60776|MetaCyc:RXN1F-162									molecular_function											owl:Class	
GO:1990085	biolink:NamedThing	Hda-beta clamp complex	A protein complex involved in inactivating the function of DnaA and thereby preventing multiple events of replication initiation. In E. coli, this complex is composed of the beta clamp (DnaN) and Hda.	tmpzr1t_l9r_go_relaxed.owl	Hda-dpo3b complex|Hda-DnaN complex							bhm	2013-04-30T11:53:18Z					cellular_component											owl:Class	
GO:1990078	biolink:NamedThing	replication inhibiting complex	A protein complex that inhibits multiple events of replication initiation during one replication cycle.	tmpzr1t_l9r_go_relaxed.owl								bhm	2013-04-26T13:07:03Z					cellular_component											owl:Class	
GO:0048380	biolink:NamedThing	negative regulation of lateral mesodermal cell fate specification	Any process that stops, prevents, or reduces the frequency, rate or extent of lateral mesoderm cell fate specification.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of lateral plate mesodermal cell fate specification|downregulation of lateral mesodermal cell fate specification|down regulation of lateral mesodermal cell fate specification|inhibition of lateral mesodermal cell fate specification|down-regulation of lateral mesodermal cell fate specification													biological_process											owl:Class	
GO:0042662	biolink:NamedThing	negative regulation of mesodermal cell fate specification	Any process that stops, prevents, or reduces the frequency, rate or extent of mesoderm cell fate specification.	tmpzr1t_l9r_go_relaxed.owl	down regulation of mesodermal cell fate specification|suppression of mesodermal cell fate|down-regulation of mesodermal cell fate specification|downregulation of mesodermal cell fate specification|inhibition of mesodermal cell fate specification													biological_process											owl:Class	
GO:1900334	biolink:NamedThing	negative regulation of methane biosynthetic process from 3-(methylthio)propionic acid	Any process that stops, prevents or reduces the frequency, rate or extent of methane biosynthetic process from 3-(methylthio)propionic acid.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of methane biosynthetic process from 3-(methylthio)propionic acid|inhibition of methane biosynthetic process from 3-(methylthio)propionic acid|down regulation of methane biosynthetic process from 3-(methylthio)propionic acid|downregulation of methane biosynthetic process from 3-(methylthio)propionic acid							tt	2012-04-06T01:56:23Z					biological_process											owl:Class	
GO:1901856	biolink:NamedThing	negative regulation of cellular respiration	Any process that stops, prevents or reduces the frequency, rate or extent of cellular respiration.	tmpzr1t_l9r_go_relaxed.owl	down regulation of oxidative metabolism|negative regulation of respiration|inhibition of cellular respiration|downregulation of respiration|down-regulation of oxidative metabolic process|down regulation of respiration|downregulation of oxidative metabolism|down-regulation of oxidative metabolism|down-regulation of cellular respiration|inhibition of oxidative metabolic process|negative regulation of oxidative metabolism|down regulation of oxidative metabolic process|negative regulation of oxidative metabolic process|down regulation of cellular respiration|downregulation of cellular respiration|down-regulation of respiration|inhibition of respiration|downregulation of oxidative metabolic process|inhibition of oxidative metabolism							yaf	2013-02-01T09:56:23Z					biological_process											owl:Class	
GO:0045583	biolink:NamedThing	regulation of cytotoxic T cell differentiation	Any process that modulates the frequency, rate or extent of cytotoxic T cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	regulation of cytotoxic T cell development|regulation of cytotoxic T lymphocyte differentiation|regulation of cytotoxic T-lymphocyte differentiation|regulation of cytotoxic T-cell differentiation					Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.								biological_process											owl:Class	
GO:0034255	biolink:NamedThing	regulation of urea metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving urea.	tmpzr1t_l9r_go_relaxed.owl	regulation of urea metabolism													biological_process											owl:Class	
GO:0002750	biolink:NamedThing	antigen processing and presentation following macropinocytosis	Antigen processing and presentation which is initiated by uptake of antigen via macropinocytosis.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0015552	biolink:NamedThing	propionate transmembrane transporter activity	Enables the transfer of propionate from one side of a membrane to the other. Propionate (or propanoate) is the organic acid CH3-CH2-COOH.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1900988	biolink:NamedThing	ajmaline biosynthetic process	The chemical reactions and pathways resulting in the formation of ajmaline.	tmpzr1t_l9r_go_relaxed.owl	ajmaline anabolism|ajmaline synthesis|ajmaline biosynthesis|ajmaline formation							yaf	2012-06-14T09:47:33Z					biological_process											owl:Class	
GO:0034693	biolink:NamedThing	U11/U12 snRNP	A ribonucleoprotein complex that is formed by the association of the U11 and U12 small nuclear ribonucleoproteins.	tmpzr1t_l9r_go_relaxed.owl	18S U11/U12 snRNP|snRNP U11/U12													cellular_component											owl:Class	
GO:0097525	biolink:NamedThing	spliceosomal snRNP complex	A small ribonucleoprotein complex involved in formation of the spliceosome.	tmpzr1t_l9r_go_relaxed.owl								pr	2013-10-18T15:57:45Z					cellular_component											owl:Class	
GO:0072125	biolink:NamedThing	negative regulation of glomerular mesangial cell proliferation	Any process that decreases the frequency, rate or extent of glomerular mesangial cell proliferation.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-02-22T01:48:49Z					biological_process											owl:Class	
GO:0016710	biolink:NamedThing	trans-cinnamate 4-monooxygenase activity	Catalysis of the reaction: trans-cinnamate + NADPH + H+ + O2 = 4-hydroxycinnamate + NADP+ + H2O.	tmpzr1t_l9r_go_relaxed.owl	cinnamic 4-hydroxylase activity|cinnamic acid 4-monooxygenase activity|hydroxylase, cinnamate 4-|cinnamic acid 4-hydroxylase activity|cinnamate 4-hydroxylase activity|cytochrome P450 cinnamate 4-hydroxylase activity|CA4H activity|cinnamate 4-monooxygenase activity|t-cinnamic acid hydroxylase activity|oxygenase, cinnamate 4-mono-|cinnamate hydroxylase activity|trans-cinnamate,NADPH:oxygen oxidoreductase (4-hydroxylating)|trans-cinnamate 4-hydroxylase activity|trans-cinnamic acid 4-hydroxylase activity|cinnamic acid p-hydroxylase activity				MetaCyc:TRANS-CINNAMATE-4-MONOOXYGENASE-RXN|RHEA:10608|EC:1.14.14.91									molecular_function											owl:Class	
GO:1904218	biolink:NamedThing	negative regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity	Any process that stops, prevents or reduces the frequency, rate or extent of CDP-diacylglycerol-serine O-phosphatidyltransferase activity.	tmpzr1t_l9r_go_relaxed.owl	down regulation of phosphatidylserine synthetase activity|downregulation of CDP-diacylglycerol:L-serine 3-O-phosphatidyltransferase activity|negative regulation of PS synthase activity|negative regulation of CDP-diacylglycerol:L-serine 3-O-phosphatidyltransferase activity|downregulation of cytidine diphosphoglyceride-serine O-phosphatidyltransferase activity|negative regulation of CDP-diglycerine-serine O-phosphatidyltransferase activity|downregulation of phosphatidylserine synthase activity|down-regulation of cytidine diphosphoglyceride-serine O-phosphatidyltransferase activity|down regulation of CDP-diacylglycerol:L-serine 3-O-phosphatidyltransferase activity|down-regulation of cytidine 5'-diphospho-1,2-diacyl-sn-glycerol:L-serine O-phosphatidyltransferase activity|down regulation of CDPdiglyceride-serine O-phosphatidyltransferase activity|negative regulation of cytidine diphosphoglyceride-serine O-phosphatidyltransferase activity|negative regulation of phosphatidylserine synthase activity|downregulation of CDP-diglyceride-L-serine phosphatidyltransferase activity|down-regulation of CDP-diglycerine-serine O-phosphatidyltransferase activity|negative regulation of CDP-diacylglycerol-L-serine O-phosphatidyltransferase activity|inhibition of CDP-diacylglycerol-L-serine O-phosphatidyltransferase activity|negative regulation of cytidine 5'-diphospho-1,2-diacyl-sn-glycerol:L-serine O-phosphatidyltransferase activity|down regulation of cytidine 5'-diphospho-1,2-diacyl-sn-glycerol (CDPdiglyceride):L-serine O-phosphatidyltransferase activity|inhibition of CDP-diacylglycerol-serine O-phosphatidyltransferase activity|downregulation of CDP-diacylglycerol-L-serine O-phosphatidyltransferase activity|inhibition of CDP-diacylglycerol:L-serine 3-O-phosphatidyltransferase activity|downregulation of CDPdiglyceride-serine O-phosphatidyltransferase activity|inhibition of phosphatidylserine synthase activity|inhibition of PS synthase activity|down-regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity|down regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity|inhibition of cytidine 5'-diphospho-1,2-diacyl-sn-glycerol (CDPdiglyceride):L-serine O-phosphatidyltransferase activity|down regulation of PS synthase activity|down regulation of CDP-diglyceride-L-serine phosphatidyltransferase activity|negative regulation of cytidine 5'-diphospho-1,2-diacyl-sn-glycerol (CDPdiglyceride):L-serine O-phosphatidyltransferase activity|down regulation of CDP-diglyceride:serine phosphatidyltransferase activity|downregulation of CDP-diglyceride:serine phosphatidyltransferase activity|down-regulation of CDP-diacylglycerol-L-serine O-phosphatidyltransferase activity|downregulation of PS synthase activity|down regulation of phosphatidylserine synthase activity|negative regulation of CDP-diglyceride:serine phosphatidyltransferase activity|downregulation of CDP-diglycerine-serine O-phosphatidyltransferase activity|down regulation of CDP-diacylglycerol-L-serine O-phosphatidyltransferase activity|downregulation of cytidine 5'-diphospho-1,2-diacyl-sn-glycerol:L-serine O-phosphatidyltransferase activity|down regulation of cytidine diphosphoglyceride-serine O-phosphatidyltransferase activity|down-regulation of CDP-diglyceride:serine phosphatidyltransferase activity|negative regulation of phosphatidylserine synthetase activity|downregulation of phosphatidylserine synthetase activity|negative regulation of CDP-diglyceride-L-serine phosphatidyltransferase activity|down-regulation of cytidine 5'-diphospho-1,2-diacyl-sn-glycerol (CDPdiglyceride):L-serine O-phosphatidyltransferase activity|inhibition of CDPdiacylglycerol-serine O-phosphatidyltransferase activity|negative regulation of CDPdiglyceride-serine O-phosphatidyltransferase activity|down regulation of CDP-diglycerine-serine O-phosphatidyltransferase activity|inhibition of CDP-diglyceride:serine phosphatidyltransferase activity|inhibition of CDP-diglycerine-serine O-phosphatidyltransferase activity|inhibition of CDPdiglyceride-serine O-phosphatidyltransferase activity|down-regulation of CDP-diglyceride-L-serine phosphatidyltransferase activity|down-regulation of CDP-diacylglycerol:L-serine 3-O-phosphatidyltransferase activity|down regulation of cytidine 5'-diphospho-1,2-diacyl-sn-glycerol:L-serine O-phosphatidyltransferase activity|inhibition of phosphatidylserine synthetase activity|down regulation of CDPdiacylglycerol-serine O-phosphatidyltransferase activity|downregulation of CDPdiacylglycerol-serine O-phosphatidyltransferase activity|downregulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity|negative regulation of CDPdiacylglycerol-serine O-phosphatidyltransferase activity|inhibition of CDP-diglyceride-L-serine phosphatidyltransferase activity|down-regulation of PS synthase activity|down-regulation of CDPdiacylglycerol-serine O-phosphatidyltransferase activity|down-regulation of phosphatidylserine synthetase activity|down-regulation of phosphatidylserine synthase activity|inhibition of cytidine 5'-diphospho-1,2-diacyl-sn-glycerol:L-serine O-phosphatidyltransferase activity|inhibition of cytidine diphosphoglyceride-serine O-phosphatidyltransferase activity|down-regulation of CDPdiglyceride-serine O-phosphatidyltransferase activity|downregulation of cytidine 5'-diphospho-1,2-diacyl-sn-glycerol (CDPdiglyceride):L-serine O-phosphatidyltransferase activity					Serinc proteins form a complex with serine and sphingolipid biosynthesis enzymes and regulates their activity through regulation of availability of the substrate		rl	2015-05-15T08:18:29Z					biological_process											owl:Class	
GO:2001044	biolink:NamedThing	regulation of integrin-mediated signaling pathway	Any process that modulates the frequency, rate or extent of integrin-mediated signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	regulation of integrin-mediated signalling pathway							bf	2011-08-31T03:49:11Z					biological_process											owl:Class	
GO:0042976	biolink:NamedThing	activation of Janus kinase activity	The process of introducing a phosphate group to a tyrosine residue of a JAK (Janus Activated Kinase) protein, thereby activating it.	tmpzr1t_l9r_go_relaxed.owl	tyrosine phosphorylation of JAK protein|activation of JAK1 protein|activation of JAK protein by tyrosine phosphorylation|activation of JAK2 protein|activation of JAK1 kinase activity|tyrosine phosphorylation of JAK1 protein|tyrosine phosphorylation of JAK2 protein|activation of JAK2 kinase activity|activation of JAK protein|positive regulation of JAK protein activity by tyrosine phosphorylation											GO:0010531|GO:0042977		biological_process											owl:Class	
GO:0018108	biolink:NamedThing	peptidyl-tyrosine phosphorylation	The phosphorylation of peptidyl-tyrosine to form peptidyl-O4'-phospho-L-tyrosine.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0039									biological_process											owl:Class	
GO:1905560	biolink:NamedThing	negative regulation of kinetochore assembly	Any process that stops, prevents or reduces the frequency, rate or extent of kinetochore assembly.	tmpzr1t_l9r_go_relaxed.owl	down regulation of centromere and kinetochore complex maturation|down-regulation of chromosome-kinetochore attachment|negative regulation of centromere/kinetochore complex maturation|inhibition of centromere/kinetochore complex maturation|down-regulation of kinetochore assembly|inhibition of kinetochore assembly|inhibition of chromosome-kinetochore attachment|downregulation of chromosome-kinetochore attachment|down regulation of kinetochore formation|negative regulation of centromere and kinetochore complex maturation|down-regulation of kinetochore formation|inhibition of kinetochore formation|downregulation of kinetochore formation|down regulation of kinetochore biogenesis|down regulation of kinetochore assembly|down regulation of chromosome-kinetochore attachment|downregulation of kinetochore assembly|downregulation of centromere/kinetochore complex maturation|down-regulation of centromere and kinetochore complex maturation|negative regulation of kinetochore formation|inhibition of centromere and kinetochore complex maturation|downregulation of centromere and kinetochore complex maturation|down-regulation of centromere/kinetochore complex maturation|negative regulation of chromosome-kinetochore attachment|down regulation of centromere/kinetochore complex maturation							hbye	2016-10-14T13:47:38Z					biological_process											owl:Class	
GO:0000760	biolink:NamedThing	adaptation to pheromone regulating conjugation with mutual genetic exchange	In organisms that undergo conjugation without cellular fusion, the process resulting in desensitization following exposure to pheromone stimulus that act to down-regulate further stimulation or block initial conjugation responses.	tmpzr1t_l9r_go_relaxed.owl	adaptation to pheromone involved conjugation without cellular fusion|desensitization to pheromone during conjugation without cellular fusion													biological_process											owl:Class	
GO:0046999	biolink:NamedThing	regulation of conjugation	Any process that modulates the rate or frequency of conjugation, the union or introduction of genetic information from compatible mating types that results in a genetically different individual.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0140360	biolink:NamedThing	cyclic-GMP-AMP transmembrane transporter activity	Enables the transfer of cyclic-GMP-AMP from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl								pg	2019-07-02T14:49:32Z					molecular_function											owl:Class	
GO:0001409	biolink:NamedThing	guanine nucleotide transmembrane transporter activity	Enables the transfer of guanine nucleotides (GMP, GDP, and GTP) from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0015351	biolink:NamedThing	bilirubin secondary active transmembrane transporter activity	Enables the transfer of bilirubin from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters.	tmpzr1t_l9r_go_relaxed.owl	bilitranslocase|bilirubin porter activity													molecular_function											owl:Class	
GO:1901707	biolink:NamedThing	leptomycin B binding	Binding to leptomycin B.	tmpzr1t_l9r_go_relaxed.owl								mah	2012-12-18T15:10:04Z					molecular_function											owl:Class	
GO:0015184	biolink:NamedThing	L-cystine transmembrane transporter activity	Enables the transfer of L-cystine from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	L-cystine transporter activity|cystine/diaminopimelate porter activity				Reactome:R-HSA-5340130									molecular_function											owl:Class	
GO:0019814	biolink:NamedThing	immunoglobulin complex	A protein complex that in its canonical form is composed of two identical immunoglobulin heavy chains and two identical immunoglobulin light chains, held together by disulfide bonds and sometimes complexed with additional proteins. An immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.	tmpzr1t_l9r_go_relaxed.owl	antibody					Note that an immunoglobulin complex has the function of antigen binding if a suitable antigen is available.								cellular_component											owl:Class	
GO:0019882	biolink:NamedThing	antigen processing and presentation	The process in which an antigen-presenting cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex.	tmpzr1t_l9r_go_relaxed.owl	antigen presentation|antigen processing				Wikipedia:Antigen_presentation							GO:0030333		biological_process											owl:Class	
GO:0002376	biolink:NamedThing	immune system process	Any process involved in the development or functioning of the immune system, an organismal system for calibrated responses to potential internal or invasive threats.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Immune_system	Note that this term is a direct child of 'biological_process ; GO:0008150' because some immune system processes are types of cellular process (GO:0009987), whereas others are types of multicellular organism process (GO:0032501).								biological_process											owl:Class	
GO:1902999	biolink:NamedThing	negative regulation of phospholipid efflux	Any process that stops, prevents or reduces the frequency, rate or extent of phospholipid efflux.	tmpzr1t_l9r_go_relaxed.owl	inhibition of phospholipid export|down-regulation of phospholipid efflux|down-regulation of phospholipid export|negative regulation of phospholipid export|downregulation of phospholipid export|downregulation of phospholipid efflux|down regulation of phospholipid efflux|inhibition of phospholipid efflux|down regulation of phospholipid export							sjp	2014-05-09T08:09:59Z					biological_process											owl:Class	
GO:1902994	biolink:NamedThing	regulation of phospholipid efflux	Any process that modulates the frequency, rate or extent of phospholipid efflux.	tmpzr1t_l9r_go_relaxed.owl	regulation of phospholipid export							sjp	2014-05-08T14:55:16Z					biological_process											owl:Class	
GO:0061044	biolink:NamedThing	negative regulation of vascular wound healing	Any process that decreases the rate, frequency, or extent of blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels and contribute to the series of events that restore integrity to damaged vasculature.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-02-25T10:24:28Z					biological_process											owl:Class	
GO:0016525	biolink:NamedThing	negative regulation of angiogenesis	Any process that stops, prevents, or reduces the frequency, rate or extent of angiogenesis.	tmpzr1t_l9r_go_relaxed.owl	down regulation of angiogenesis|downregulation of angiogenesis|down-regulation of angiogenesis|inhibition of angiogenesis													biological_process											owl:Class	
GO:0099087	biolink:NamedThing	anterograde axonal transport of messenger ribonucleoprotein complex	The directed movement of a messenger ribonucleoprotein complex along microtubules in axons, towards the presynapse.	tmpzr1t_l9r_go_relaxed.owl	anterograde axonal transport of mRNA RNP complex													biological_process											owl:Class	
GO:1901126	biolink:NamedThing	candicidin catabolic process	The chemical reactions and pathways resulting in the breakdown of candicidin.	tmpzr1t_l9r_go_relaxed.owl	candicidin catabolism|candicidin degradation|candicidin breakdown							yaf	2012-07-11T03:16:54Z					biological_process											owl:Class	
GO:1904291	biolink:NamedThing	positive regulation of mitotic DNA damage checkpoint	Any process that activates or increases the frequency, rate or extent of mitotic DNA damage checkpoint.	tmpzr1t_l9r_go_relaxed.owl	up regulation of mitotic DNA damage checkpoint|upregulation of mitotic DNA damage checkpoint|up-regulation of mitotic DNA damage checkpoint|activation of mitotic DNA damage checkpoint							kmv	2015-06-09T13:03:23Z					biological_process											owl:Class	
GO:2000003	biolink:NamedThing	positive regulation of DNA damage checkpoint	Any process that activates or increases the frequency, rate or extent of a DNA damage checkpoint.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of DNA damage response, signal transduction resulting in cell cycle arrest							jl	2010-07-15T03:25:10Z					biological_process											owl:Class	
GO:0140105	biolink:NamedThing	interleukin-10-mediated signaling pathway	A series of molecular signals initiated by the binding of interleukin-10 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.	tmpzr1t_l9r_go_relaxed.owl	interleukin-10-mediated signalling pathway|IL-10-mediated signaling pathway							pg	2017-09-22T16:04:42Z					biological_process											owl:Class	
GO:0004968	biolink:NamedThing	gonadotropin-releasing hormone receptor activity	Combining with gonadotropin-releasing hormone to initiate a change in cell activity. Gonadotropin-releasing hormone (GnRH) is a peptide hormone responsible for the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) from the anterior pituitary. GnRH is synthesized and released by the hypothalamus.	tmpzr1t_l9r_go_relaxed.owl	GnRH receptor activity|gonadotrophin-releasing hormone receptor activity													molecular_function											owl:Class	
GO:0004930	biolink:NamedThing	G protein-coupled receptor activity	Combining with an extracellular signal and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.	tmpzr1t_l9r_go_relaxed.owl	Epstein-Barr Virus-induced receptor activity|orphan G-protein coupled receptor activity|RDC1 receptor activity|super conserved receptor expressed in brain receptor activity|G-protein linked receptor activity|G protein coupled receptor activity|receptor activity, G-protein coupled|orphan G protein coupled receptor activity|SREB receptor|Mas proto-oncogene receptor activity|G-protein coupled receptor activity|G protein linked receptor activity|EBV-induced receptor|G-protein coupled receptor activity, unknown ligand|GPCR activity|orphan GPCR activity|ligand-dependent GPCR activity				Reactome:R-HSA-114558|Reactome:R-HSA-167408|Reactome:R-HSA-114552|Wikipedia:GPCR							GO:0001622|GO:0016526|GO:0001625|GO:0001623|GO:0001624		molecular_function											owl:Class	
GO:0047400	biolink:NamedThing	phosphonoacetate hydrolase activity	Catalysis of the reaction: H(2)O + phosphonoacetate = acetate + H(+) + phosphate.	tmpzr1t_l9r_go_relaxed.owl	phosphonoacetate phosphonohydrolase activity				EC:3.11.1.2|RHEA:16749|KEGG_REACTION:R00318|MetaCyc:3.11.1.2-RXN									molecular_function											owl:Class	
GO:0016827	biolink:NamedThing	hydrolase activity, acting on acid carbon-phosphorus bonds	Catalysis of the hydrolysis of any acid carbon-phosphorus bond.	tmpzr1t_l9r_go_relaxed.owl					EC:3.11.-.-									molecular_function											owl:Class	
GO:0017183	biolink:NamedThing	peptidyl-diphthamide biosynthetic process from peptidyl-histidine	The modification of peptidyl-histidine to 2'-(3-carboxamido-3-(trimethylammonio)propyl)-L-histidine, known as diphthamide, found in translation elongation factor EF-2. The process occurs in eukaryotes and archaea but not eubacteria.	tmpzr1t_l9r_go_relaxed.owl	peptidyl-diphthamide formation from peptidyl-histidine|peptidyl-diphthamide anabolism from peptidyl-histidine|peptidyl-diphthamide synthesis from peptidyl-histidine				RESID:AA0040									biological_process											owl:Class	
GO:1900247	biolink:NamedThing	regulation of cytoplasmic translational elongation	Any process that modulates the frequency, rate or extent of cytoplasmic translational elongation.	tmpzr1t_l9r_go_relaxed.owl								vw	2012-04-03T05:07:02Z					biological_process											owl:Class	
GO:0052644	biolink:NamedThing	chlorophyllide a metabolic process	The chemical reactions and pathways involving chlorophyllide a, a chlorophyll lacking the terpenoid side chain, which is the functional parent of chlorophyll a.	tmpzr1t_l9r_go_relaxed.owl	chlorophyllide a metabolism													biological_process											owl:Class	
GO:1903791	biolink:NamedThing	uracil transmembrane transport	The process in which uracil is transported across a membrane.	tmpzr1t_l9r_go_relaxed.owl								vw	2015-01-12T10:15:25Z					biological_process											owl:Class	
GO:0015857	biolink:NamedThing	uracil transport	The directed movement of uracil, 2,4-dioxopyrimidine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0098002	biolink:NamedThing	receptor-mediated bacteriophage irreversible attachment to host cell	The processes by which a bacteriophage initially commits to infection by binding the host receptor irreversibly. Disruption of the phage:cell complex at this step results in the loss of infective phage virions since the process is characterized by conformational changes of bacteriophage head and tail proteins and injection of bacteriophage proteins into the infected cell.	tmpzr1t_l9r_go_relaxed.owl	irreversible bacteriophage attachment, binding of host cell surface receptor|phage irreversible adsorption							bm						biological_process											owl:Class	
GO:0098670	biolink:NamedThing	entry receptor-mediated virion attachment to host cell	The process by which a virion attaches to a host cell by binding to a receptor on the host cell surface that mediates/triggers viral entry by endocytosis/pinocytosis or by inducing fusion/penetration.	tmpzr1t_l9r_go_relaxed.owl	viral attachment to host entry receptor				VZ:3942			dos	2017-01-16T13:18:27Z					biological_process											owl:Class	
GO:0042616	biolink:NamedThing	paclitaxel metabolic process	The chemical reactions and pathways involving paclitaxel, a tetracyclic diterpenoid isolated originally from the bark of the Pacific yew tree, Taxus brevifolia.	tmpzr1t_l9r_go_relaxed.owl	taxol metabolism|paclitaxel metabolism|taxol metabolic process													biological_process											owl:Class	
GO:0004694	biolink:NamedThing	eukaryotic translation initiation factor 2alpha kinase activity	Catalysis of the reaction: ATP + [eukaryotic translation initiation factor 2 alpha subunit] = ADP + [eukaryotic translation initiation factor 2 alpha subunit] phosphate.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0045182	biolink:NamedThing	translation regulator activity	Any molecular function involved in the initiation, activation, perpetuation, repression or termination of polypeptide synthesis at the ribosome.	tmpzr1t_l9r_go_relaxed.owl	translation factor activity													molecular_function											owl:Class	
GO:0060417	biolink:NamedThing	yolk	The cytoplasmic part that serves as a nutrient reserve or energy source for the developing embryo.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:1902413	biolink:NamedThing	negative regulation of mitotic cytokinesis	Any process that stops, prevents or reduces the frequency, rate or extent of mitotic cytokinesis.	tmpzr1t_l9r_go_relaxed.owl	down regulation of mitotic cytokinesis|downregulation of mitotic cytokinesis|down-regulation of cytokinesis after mitosis|negative regulation of cytokinesis after mitosis|down-regulation of mitotic cytokinesis|down regulation of cytokinesis after mitosis|downregulation of cytokinesis after mitosis|inhibition of cytokinesis after mitosis|inhibition of mitotic cytokinesis							jl	2013-09-12T14:11:59Z					biological_process											owl:Class	
GO:0010091	biolink:NamedThing	trichome branching	Any process involved in the formation of branches in plant hair cells. An example of this process is found in Arabidopsis thaliana.	tmpzr1t_l9r_go_relaxed.owl												GO:0048274		biological_process											owl:Class	
GO:1903898	biolink:NamedThing	negative regulation of PERK-mediated unfolded protein response	Any process that stops, prevents or reduces the frequency, rate or extent of the PERK-mediated unfolded protein response.	tmpzr1t_l9r_go_relaxed.owl	down regulation of PKR-like ER kinase signal transduction|inhibition of PERK branch of UPR|down-regulation of PKR-like ER kinase signal transduction|down regulation of endoplasmic reticulum unfolded protein response; PERK signaling|down regulation of PERK-mediated unfolded protein response|inhibition of PKR-like ER kinase signal transduction|downregulation of PERK signaling in response to endoplasmic reticulum stress|downregulation of PERK branch of UPR|down-regulation of PERK signaling in response to endoplasmic reticulum stress|inhibition of PERK signaling in response to endoplasmic reticulum stress|negative regulation of PERK branch of UPR|down-regulation of PERK-mediated unfolded protein response|downregulation of PERK-mediated unfolded protein response|down-regulation of endoplasmic reticulum unfolded protein response; PERK signaling|inhibition of endoplasmic reticulum unfolded protein response; PERK signaling|down-regulation of PERK branch of UPR|inhibition of PERK-mediated unfolded protein response|downregulation of endoplasmic reticulum unfolded protein response; PERK signaling|negative regulation of PERK signaling in response to endoplasmic reticulum stress|downregulation of UPR signaling by PERK stress sensor|down regulation of PERK signaling in response to endoplasmic reticulum stress|negative regulation of endoplasmic reticulum unfolded protein response; PERK signaling|down-regulation of UPR signaling by PERK stress sensor|down regulation of UPR signaling by PERK stress sensor|down regulation of PERK branch of UPR|inhibition of UPR signaling by PERK stress sensor|negative regulation of UPR signaling by PERK stress sensor|negative regulation of PKR-like ER kinase signal transduction|negative regulation of EIF2AK3-mediated unfolded protein response|downregulation of PKR-like ER kinase signal transduction							bf	2015-02-09T10:18:23Z					biological_process											owl:Class	
GO:1900102	biolink:NamedThing	negative regulation of endoplasmic reticulum unfolded protein response	Any process that stops, prevents or reduces the frequency, rate or extent of endoplasmic reticulum unfolded protein response.	tmpzr1t_l9r_go_relaxed.owl	down regulation of ER unfolded protein response|negative regulation of SREBP-mediated signalling pathway|downregulation of SREBP-mediated signalling pathway|inhibition of erUPR|down-regulation of erUPR|inhibition of SREBP-mediated signalling pathway|downregulation of ER unfolded protein response|downregulation of endoplasmic reticulum unfolded protein response|inhibition of ER unfolded protein response|inhibition of endoplasmic reticulum unfolded protein response|down regulation of endoplasmic reticulum unfolded protein response|down-regulation of SREBP-mediated signalling pathway|downregulation of erUPR|negative regulation of erUPR|down regulation of erUPR|down-regulation of ER unfolded protein response|negative regulation of ER unfolded protein response|down-regulation of endoplasmic reticulum unfolded protein response|down regulation of SREBP-mediated signalling pathway							ppm	2012-02-15T11:15:31Z					biological_process											owl:Class	
GO:2001289	biolink:NamedThing	lipid X metabolic process	The chemical reactions and pathways involving lipid X, 2,3-diacylglucosamine 1-phosphate.	tmpzr1t_l9r_go_relaxed.owl	2,3-Bis(beta-hydoroxymyristoyl)-beta-D-glucosaminyl 1-phosphate metabolic process|2,3-Bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate metabolism|2,3-Bis(beta-hydoroxymyristoyl)-beta-D-glucosaminyl 1-phosphate metabolism|2,3-Bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate metabolic process|2-deoxy-3-O-[(3R)-3-hydroxytetradecanoyl]-2-{[(3R)-3-hydroxytetradecanoyl]amino}-1-O-phosphono-alpha-D-glucopyranose metabolism|2-deoxy-3-O-[(3R)-3-hydroxytetradecanoyl]-2-{[(3R)-3-hydroxytetradecanoyl]amino}-1-O-phosphono-alpha-D-glucopyranose metabolic process|lipid X metabolism							tb	2012-01-13T11:28:58Z					biological_process											owl:Class	
GO:0044695	biolink:NamedThing	Dsc E3 ubiquitin ligase complex	An E3 ubiquitin ligase complex localized to the ER and Golgi membrane. In fission yeast comprises Dsc1, 2, 3 and 4. Involved in the processes of fission yeast sre1 (human SREBP) transcriptional activator proteolytic cleavage, the multivesicular body (MVB) pathway, and a post-endoplasmic reticulum pathway for protein catabolism.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-08-16T13:41:48Z					cellular_component											owl:Class	
GO:0061279	biolink:NamedThing	epithelial cell migration involved in mesonephric distal tubule morphogenesis	The orderly movement of epithelial cells within a renal tubule that contributes to mesonephric distal tubule morphogenesis.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-09-02T01:20:56Z					biological_process											owl:Class	
GO:0072441	biolink:NamedThing	response to meiotic DNA replication checkpoint signaling	A process that occurs in response to signals generated as a result of meiotic DNA replication checkpoint signaling.	tmpzr1t_l9r_go_relaxed.owl	meiotic DNA replication checkpoint effector process|response to signal involved in meiotic DNA replication checkpoint							mah	2010-12-08T04:59:26Z					biological_process											owl:Class	
GO:0072410	biolink:NamedThing	response to meiotic cell cycle checkpoint signaling	A process that acts directly to delay or stop progression through the cell cycle in response to signals generated as a result of meiotic cell cycle checkpoint signaling; contributes to a meiotic cell cycle checkpoint.	tmpzr1t_l9r_go_relaxed.owl	meiotic cell cycle checkpoint effector process|response to signal involved in meiotic cell cycle checkpoint							mah	2010-12-08T03:48:38Z					biological_process											owl:Class	
GO:1902334	biolink:NamedThing	fructose export from vacuole to cytoplasm	The directed movement of fructose from vacuole to cytoplasm.	tmpzr1t_l9r_go_relaxed.owl	fructose transport from vacuole to cytoplasm							tb	2013-07-26T22:18:12Z					biological_process											owl:Class	
GO:0015755	biolink:NamedThing	fructose transmembrane transport	The directed movement of fructose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Fructose exists in a open chain form or as a ring compound. D-fructose is the sweetest of the sugars and is found free in a large number of fruits and honey.	tmpzr1t_l9r_go_relaxed.owl	fructose transport													biological_process											owl:Class	
GO:0010372	biolink:NamedThing	positive regulation of gibberellin biosynthetic process	Any process that activates, maintains or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of gibberellins.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of gibberellic acid biosynthetic process													biological_process											owl:Class	
GO:0010371	biolink:NamedThing	regulation of gibberellin biosynthetic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of gibberellins.	tmpzr1t_l9r_go_relaxed.owl	regulation of gibberellic acid biosynthetic process													biological_process											owl:Class	
GO:0034451	biolink:NamedThing	centriolar satellite	A small (70-100 nm) cytoplasmic granule that contains a number of centrosomal proteins; centriolar satellites traffic toward microtubule minus ends and are enriched near the centrosome.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0043642	biolink:NamedThing	novobiocin biosynthetic process	The chemical reactions and pathways resulting in the formation of novobiocin, a coumarin antibiotic produced by the bacterium Gyrasestreptomyces spheroides, that acts by inhibiting DNA gyrase.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Novobiocin									biological_process											owl:Class	
GO:0099177	biolink:NamedThing	regulation of trans-synaptic signaling	Any process that modulates the frequency, rate or extent of trans-synaptic signaling.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0071719	biolink:NamedThing	sodium-independent leukotriene transport	The directed, sodium-independent, movement of leukotrienes into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Leukotrienes are linear C20 endogenous metabolites of arachidonic acid (icosa-5,8,11,14-tetraenoic acid) containing a terminal carboxy function and four or more double bonds (three or more of which are conjugated) as well as other functional groups.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-03-10T03:08:42Z					biological_process											owl:Class	
GO:0071716	biolink:NamedThing	leukotriene transport	The directed movement of leukotrienes into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Leukotrienes are linear C20 endogenous metabolites of arachidonic acid (icosa-5,8,11,14-tetraenoic acid) containing a terminal carboxy function and four or more double bonds (three or more of which are conjugated) as well as other functional groups.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-03-10T02:53:59Z					biological_process											owl:Class	
GO:0060362	biolink:NamedThing	flight involved in flight behavior	Self-propelled movement of an organism from one location to another through the air that is part of the organism's response to external or internal stimuli resulting in flight.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0031987	biolink:NamedThing	locomotion involved in locomotory behavior	Self-propelled movement of a cell or organism from one location to another in a behavioral context; the aspect of locomotory behavior having to do with movement.	tmpzr1t_l9r_go_relaxed.owl	locomotion during locomotory behaviour													biological_process											owl:Class	
GO:0015850	biolink:NamedThing	organic hydroxy compound transport	The directed movement of an organic hydroxy compound (organic alcohol) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. An organic hydroxy compound is an organic compound having at least one hydroxy group attached to a carbon atom.	tmpzr1t_l9r_go_relaxed.owl	organic alcohol transport													biological_process											owl:Class	
GO:1904909	biolink:NamedThing	positive regulation of maintenance of mitotic sister chromatid cohesion, telomeric	Any process that activates or increases the frequency, rate or extent of maintenance of mitotic sister chromatid cohesion, telomeric.	tmpzr1t_l9r_go_relaxed.owl	activation of maintenance of mitotic sister chromatid cohesion, telomeric|up regulation of maintenance of telomeric mitotic sister chromatin cohesion|positive regulation of maintenance of mitotic sister chromatin cohesion at telomere|up regulation of maintenance of sister chromatin cohesion at telomere at mitosis|upregulation of maintenance of mitotic sister chromatin cohesion at telomere|up regulation of maintenance of mitotic sister chromatin cohesion at telomere|activation of maintenance of sister chromatin cohesion at telomere at mitosis|positive regulation of maintenance of telomeric mitotic sister chromatin cohesion|up regulation of maintenance of mitotic sister chromatid cohesion, telomeric|activation of maintenance of mitotic sister chromatin cohesion at telomere|upregulation of maintenance of mitotic sister chromatid cohesion, telomeric|up-regulation of maintenance of telomeric mitotic sister chromatin cohesion|upregulation of maintenance of sister chromatin cohesion at telomere at mitosis|up-regulation of maintenance of mitotic sister chromatin cohesion at telomere|positive regulation of maintenance of sister chromatin cohesion at telomere at mitosis|up-regulation of maintenance of sister chromatin cohesion at telomere at mitosis|upregulation of maintenance of telomeric mitotic sister chromatin cohesion|up-regulation of maintenance of mitotic sister chromatid cohesion, telomeric|activation of maintenance of telomeric mitotic sister chromatin cohesion							rph	2016-01-19T10:30:43Z					biological_process											owl:Class	
GO:1904907	biolink:NamedThing	regulation of maintenance of mitotic sister chromatid cohesion, telomeric	Any process that modulates the frequency, rate or extent of maintenance of mitotic sister chromatid cohesion, telomeric.	tmpzr1t_l9r_go_relaxed.owl	regulation of maintenance of telomeric mitotic sister chromatin cohesion|regulation of maintenance of sister chromatin cohesion at telomere at mitosis|regulation of maintenance of mitotic sister chromatin cohesion at telomere							rph	2016-01-19T10:30:29Z					biological_process											owl:Class	
GO:0042857	biolink:NamedThing	chrysobactin metabolic process	The chemical reactions and pathways involving the siderophore chrysobactin (alpha-N-(2,3-dihydroxybenzoyl)-D-lysyl-L-serine).	tmpzr1t_l9r_go_relaxed.owl	chrysobactin metabolism													biological_process											owl:Class	
GO:1901374	biolink:NamedThing	acetate ester transport	The directed movement of an acetate ester into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl								bf	2012-09-28T10:42:13Z					biological_process											owl:Class	
GO:0071702	biolink:NamedThing	organic substance transport	The directed movement of organic substances into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or pore. An organic substance is a molecular entity that contains carbon.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-03-08T02:15:14Z					biological_process											owl:Class	
GO:0034635	biolink:NamedThing	glutathione transport	The directed movement of glutathione, the tripeptide glutamylcysteinylglycine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0042939	biolink:NamedThing	tripeptide transport	The directed movement of a tripeptide, a compound containing three amino acids linked together by peptide bonds, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0010123	biolink:NamedThing	acetate catabolic process to butyrate, ethanol, acetone and butanol	The anaerobic chemical reactions and pathways resulting in the breakdown of acetate to form butyrate, ethanol, acetone and butanol.	tmpzr1t_l9r_go_relaxed.owl	acetate fermentation to butyrate, ethanol, acetone and butanol				MetaCyc:CENTFERM-PWY									biological_process											owl:Class	
GO:0043443	biolink:NamedThing	acetone metabolic process	The chemical reactions and pathways involving acetone, propan-2-one.	tmpzr1t_l9r_go_relaxed.owl	2-propanone metabolism|propan-2-one metabolism|dimethyl ketone metabolic process|propan-2-one metabolic process|2-propanone metabolic process|dimethyl ketone metabolism|acetone metabolism													biological_process											owl:Class	
GO:0060331	biolink:NamedThing	negative regulation of response to interferon-gamma	Any process that decreases the rate, frequency or extent of a response to interferon-gamma. Response to interferon gamma is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-gamma stimulus.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of response to immune interferon|negative regulation of response to type II interferon|negative regulation of response to type II IFN|negative regulation of response to gamma-interferon													biological_process											owl:Class	
GO:0030193	biolink:NamedThing	regulation of blood coagulation	Any process that modulates the frequency, rate or extent of blood coagulation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0050818	biolink:NamedThing	regulation of coagulation	Any process that modulates the frequency, rate or extent of coagulation, the process in which a fluid solution, or part of it, changes into a solid or semisolid mass.	tmpzr1t_l9r_go_relaxed.owl	regulation of clotting													biological_process											owl:Class	
GO:0019627	biolink:NamedThing	urea metabolic process	The chemical reactions and pathways involving urea, the water soluble compound O=C-(NH2)2.	tmpzr1t_l9r_go_relaxed.owl	urea metabolism													biological_process											owl:Class	
GO:0043603	biolink:NamedThing	cellular amide metabolic process	The chemical reactions and pathways involving an amide, any derivative of an oxoacid in which an acidic hydroxy group has been replaced by an amino or substituted amino group, as carried out by individual cells.	tmpzr1t_l9r_go_relaxed.owl	amide metabolism													biological_process											owl:Class	
GO:0140192	biolink:NamedThing	regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process	Any process that modulates the frequency, rate or extent of an adenylate cyclase-activating adrenergic receptor signaling pathway involved in some heart process.	tmpzr1t_l9r_go_relaxed.owl								pg	2018-02-15T19:06:38Z					biological_process											owl:Class	
GO:0106070	biolink:NamedThing	regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway	Any process that modulates the frequency, rate or extent of an adenylate cyclase-activating G protein-coupled receptor signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	regulation of adenylate cyclase-activating G-protein coupled receptor signaling pathway							hjd	2017-11-28T18:28:22Z					biological_process											owl:Class	
GO:0072506	biolink:NamedThing	trivalent inorganic anion homeostasis	Any process involved in the maintenance of an internal steady state of trivalent inorganic anions within an organism or cell.	tmpzr1t_l9r_go_relaxed.owl						Note that this term was split from 'di-, tri-valent inorganic anion homeostasis ; GO:0055061' (sibling term 'divalent inorganic anion homeostasis' ; GO:0072505').		mah	2010-12-16T01:39:39Z					biological_process											owl:Class	
GO:0098771	biolink:NamedThing	inorganic ion homeostasis	Any process involved in the maintenance of an internal steady state of inorganic ions within an organism or cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0070808	biolink:NamedThing	regulation of Hulle cell development	Any process that modulates the frequency, rate or extent of Hulle cell development, a process that leads to the formation of Hulle cells. Hulle cells are specialized multinucleate cells that originate from a nest-like aggregation of hyphae during sexual development and serve as nurse cells to the developing cleistothecium, or fruiting body.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-07-08T04:51:33Z					biological_process											owl:Class	
GO:1901860	biolink:NamedThing	positive regulation of mitochondrial DNA metabolic process	Any process that activates or increases the frequency, rate or extent of mitochondrial DNA metabolic process.	tmpzr1t_l9r_go_relaxed.owl	upregulation of mitochondrial DNA metabolism|activation of mtDNA metabolic process|activation of mitochondrial DNA metabolic process|up regulation of mitochondrial DNA metabolic process|activation of mitochondrial DNA metabolism|up-regulation of mitochondrial DNA metabolism|positive regulation of mitochondrial DNA metabolism|up regulation of mtDNA metabolism|up-regulation of mtDNA metabolism|positive regulation of mtDNA metabolic process|positive regulation of mtDNA metabolism|upregulation of mtDNA metabolic process|activation of mtDNA metabolism|up-regulation of mtDNA metabolic process|up regulation of mtDNA metabolic process|up-regulation of mitochondrial DNA metabolic process|up regulation of mitochondrial DNA metabolism|upregulation of mtDNA metabolism|upregulation of mitochondrial DNA metabolic process							yaf	2013-02-01T10:05:14Z					biological_process											owl:Class	
GO:1904711	biolink:NamedThing	regulation of Wnt-Frizzled-LRP5/6 complex assembly	Any process that modulates the frequency, rate or extent of Wnt-Frizzled-LRP5/6 complex assembly.	tmpzr1t_l9r_go_relaxed.owl	regulation of Wnt receptor complex assembly|regulation of WNT-FZD-LRP5 complex assembly|regulation of Wnt-FZD-LRP5/6 trimeric complex assembly|regulation of Wnt-induced Frizzled-LRP5/6 complex formation|regulation of Wnt-induced Frizzled-LRP5/6 complex assembly|regulation of Frizzled-LRP5/6 complex assembly|regulation of Wnt-FZD-LRP5/6 trimeric complex formation|regulation of WNT-FZD-LRP5 complex formation|regulation of WNT-FZD-LRP6 complex formation|regulation of WNT-FZD-LRP6 complex assembly|regulation of Frizzled-LRP5/6 complex formation							bf	2015-10-05T14:02:22Z					biological_process											owl:Class	
GO:0002507	biolink:NamedThing	tolerance induction	A process that directly activates any of the steps required for tolerance, a physiologic state in which the immune system does not react destructively against the components of an organism that harbors it or against antigens that are introduced to it.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0022408	biolink:NamedThing	negative regulation of cell-cell adhesion	Any process that stops, prevents or reduces the rate or extent of cell adhesion to another cell.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of cell-cell adhesion|down regulation of cell-cell adhesion|downregulation of cell-cell adhesion|inhibition of cell-cell adhesion													biological_process											owl:Class	
GO:0090370	biolink:NamedThing	negative regulation of cholesterol efflux	Any process that decreases the frequency, rate or extent of cholesterol efflux. Cholesterol efflux is the directed movement of cholesterol, cholest-5-en-3-beta-ol, out of a cell or organelle.	tmpzr1t_l9r_go_relaxed.owl								tb	2010-07-12T11:26:04Z					biological_process											owl:Class	
GO:0010874	biolink:NamedThing	regulation of cholesterol efflux	Any process that modulates the frequency, rate or extent of cholesterol efflux. Cholesterol efflux is the directed movement of cholesterol, cholest-5-en-3-beta-ol, out of a cell or organelle.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0048216	biolink:NamedThing	negative regulation of Golgi vesicle fusion to target membrane	Any process that stops, prevents, or reduces the frequency, rate or extent of Golgi vesicle fusion to target membrane.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of Golgi vesicle fusion to target membrane|down regulation of Golgi vesicle fusion to target membrane|downregulation of Golgi vesicle fusion to target membrane|inhibition of Golgi vesicle fusion to target membrane													biological_process											owl:Class	
GO:0035477	biolink:NamedThing	regulation of angioblast cell migration involved in selective angioblast sprouting	Any process that modulates the frequency, rate or extent of angioblast cell migration involved in selective angioblast sprouting.	tmpzr1t_l9r_go_relaxed.owl								bf	2010-04-23T10:08:28Z					biological_process											owl:Class	
GO:0030334	biolink:NamedThing	regulation of cell migration	Any process that modulates the frequency, rate or extent of cell migration.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0106218	biolink:NamedThing	galactosaminogalactan biosynthetic process	The chemical reactions and pathways resulting in the formation of the exopolysaccharide galactosaminogalactan. GAG is a heteropolysaccharide composed of alpha-1,4 linked galactose, N-acetyl galactosamine (GalNAc) and galactosamine (GalN).	tmpzr1t_l9r_go_relaxed.owl	galactosaminogalactan synthesis|galactosaminogalactan biosynthesis|GAG biosynthetic process|galactosaminogalactan formation|galactosaminogalactan anabolism							hjd	2019-08-05T14:46:56Z					biological_process											owl:Class	
GO:0051278	biolink:NamedThing	fungal-type cell wall polysaccharide biosynthetic process	The chemical reactions and pathways resulting in the formation of the polysaccharides which make up the fungal-type cell wall.	tmpzr1t_l9r_go_relaxed.owl	cell wall polysaccharide synthesis|chitin- and beta-glucan-containing cell wall polysaccharide biosynthetic process|cell wall polysaccharide anabolism|cell wall polysaccharide formation													biological_process											owl:Class	
GO:0071715	biolink:NamedThing	icosanoid transport	The directed movement of icosanoids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Icosanoids are unsaturated C20 fatty acids and skeletally related compounds.	tmpzr1t_l9r_go_relaxed.owl	eicosanoid transport							mah	2010-03-10T02:47:22Z					biological_process											owl:Class	
GO:0072507	biolink:NamedThing	divalent inorganic cation homeostasis	Any process involved in the maintenance of an internal steady state of divalent cations within an organism or cell.	tmpzr1t_l9r_go_relaxed.owl						Note that this term was split from 'di-, tri-valent inorganic cation homeostasis ; GO:0055066' (sibling term 'trivalent inorganic cation homeostasis' ; GO:0072508').		mah	2010-12-16T03:22:48Z					biological_process											owl:Class	
GO:0086016	biolink:NamedThing	AV node cell action potential	An action potential that occurs in an atrioventricular node cardiac muscle cell.	tmpzr1t_l9r_go_relaxed.owl	atrioventricular node cardiac muscle cell action potential|AV node cardiac muscle cell action potential							tb	2011-11-10T08:58:56Z					biological_process											owl:Class	
GO:0033830	biolink:NamedThing	Skp1-protein-hydroxyproline N-acetylglucosaminyltransferase activity	Catalysis of the reaction: UDP-N-acetylglucosamine + Skp1-protein-hydroxyproline = UDP + Skp1-protein-O-(N-acetyl-D-glucosaminyl)hydroxyproline.	tmpzr1t_l9r_go_relaxed.owl	UDP-GlcNAc:hydroxyproline polypeptide GlcNAc-transferase activity|UDP-GlcNAc:Skp1-hydroxyproline GlcNAc-transferase activity|UDP-N-acetyl-D-glucosamine:Skp1-protein-hydroxyproline N-acetyl-D-glucosaminyl-transferase activity|UDP-N-acetylglucosamine (GlcNAc):hydroxyproline polypeptide GlcNAc-transferase activity|Skp1-HyPro GlcNAc-transferase activity				RHEA:17841|EC:2.4.1.229									molecular_function											owl:Class	
GO:0045971	biolink:NamedThing	positive regulation of juvenile hormone catabolic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of juvenile hormone.	tmpzr1t_l9r_go_relaxed.owl	up regulation of juvenile hormone catabolic process|stimulation of juvenile hormone catabolic process|upregulation of juvenile hormone catabolic process|activation of juvenile hormone catabolic process|up-regulation of juvenile hormone catabolic process|positive regulation of juvenile hormone catabolism|positive regulation of juvenile hormone breakdown|positive regulation of juvenile hormone degradation													biological_process											owl:Class	
GO:0106174	biolink:NamedThing	phagolysosome vesicle lumen	The volume enclosed by the membrane of a phagolysosome.	tmpzr1t_l9r_go_relaxed.owl								hjd	2019-02-11T19:10:46Z					cellular_component											owl:Class	
GO:0060205	biolink:NamedThing	cytoplasmic vesicle lumen	The volume enclosed by a cytoplasmic vesicle.	tmpzr1t_l9r_go_relaxed.owl	cytoplasmic membrane-enclosed vesicle lumen|cytoplasmic membrane-bounded vesicle lumen													cellular_component											owl:Class	
GO:0002759	biolink:NamedThing	regulation of antimicrobial humoral response	Any process that modulates the frequency, rate, or extent of an antimicrobial humoral response.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0032101	biolink:NamedThing	regulation of response to external stimulus	Any process that modulates the frequency, rate or extent of a response to an external stimulus.	tmpzr1t_l9r_go_relaxed.owl						Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.								biological_process											owl:Class	
GO:0045883	biolink:NamedThing	positive regulation of sulfur utilization	Any process that activates or increases the frequency, rate or extent of sulfur utilization.	tmpzr1t_l9r_go_relaxed.owl	up regulation of sulfur utilization|activation of sulfur utilization|stimulation of sulfur utilization|positive regulation of sulphur utilization|up-regulation of sulfur utilization|upregulation of sulfur utilization													biological_process											owl:Class	
GO:0000248	biolink:NamedThing	C-5 sterol desaturase activity	Catalysis of the reaction: 5,7,24(28)-ergostatrienol + O2 + NADPH = 5,7,22,24(28)-ergostatetraenol + 2 H2O + NADP+.	tmpzr1t_l9r_go_relaxed.owl	sterol-C5-desaturase activity				Reactome:R-HSA-6807053|Reactome:R-HSA-195664									molecular_function											owl:Class	
GO:0014890	biolink:NamedThing	smooth muscle atrophy	A process, occurring in smooth muscle, that is characterized by a decrease in protein content, fiber diameter, force production and fatigue resistance in response to different conditions such as starvation, aging and disuse.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:2000089	biolink:NamedThing	positive regulation of mesonephric glomerulus development	Any process that activates or increases the frequency, rate or extent of mesonephric glomerulus development.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-09-03T06:09:24Z					biological_process											owl:Class	
GO:2000087	biolink:NamedThing	regulation of mesonephric glomerulus development	Any process that modulates the frequency, rate or extent of mesonephric glomerulus development.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-09-03T06:09:19Z					biological_process											owl:Class	
GO:1905563	biolink:NamedThing	negative regulation of vascular endothelial cell proliferation	Any process that stops, prevents or reduces the frequency, rate or extent of vascular endothelial cell proliferation.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of vascular endothelial cell proliferation|downregulation of vascular endothelial cell proliferation|down regulation of vascular endothelial cell proliferation|inhibition of vascular endothelial cell proliferation							nc	2016-10-17T09:24:26Z					biological_process											owl:Class	
GO:0050029	biolink:NamedThing	L-lysine oxidase activity	Catalysis of the reaction: L-lysine + H(2)O + O(2) = 6-amino-2-oxohexanoate + H(2)O(2) + NH(4)(+).	tmpzr1t_l9r_go_relaxed.owl	L-lysine alpha-oxidase activity|L-lysine:oxygen 2-oxidoreductase (deaminating)|L-lysyl-alpha-oxidase activity				MetaCyc:PWY-5311|MetaCyc:L-LYSINE-OXIDASE-RXN|RHEA:14437|KEGG_REACTION:R00447|EC:1.4.3.14									molecular_function											owl:Class	
GO:0001716	biolink:NamedThing	L-amino-acid oxidase activity	Catalysis of the reaction: a L-amino acid + H2O + O2 = a 2-oxo acid + NH3 + hydrogen peroxide.	tmpzr1t_l9r_go_relaxed.owl	ophio-amino-acid oxidase activity|L-amino-acid:oxygen oxidoreductase (deaminating)				MetaCyc:L-AMINO-ACID-OXIDASE-RXN|Reactome:R-HSA-2160492|EC:1.4.3.2|RHEA:13781									molecular_function											owl:Class	
GO:1990251	biolink:NamedThing	nuclear exosome focus	An nuclear body involved in nuclear mRNA surveilllance. Contains at least Mmi1, or an ortholog of it, and the nuclear exosome.	tmpzr1t_l9r_go_relaxed.owl	Mmi1 nuclear focus|nuclear body	https://github.com/geneontology/go-ontology/issues/19063						al	2013-12-09T12:07:46Z					cellular_component											owl:Class	
GO:0016604	biolink:NamedThing	nuclear body	Extra-nucleolar nuclear domains usually visualized by confocal microscopy and fluorescent antibodies to specific proteins.	tmpzr1t_l9r_go_relaxed.owl					NIF_Subcellular:sao505137457									cellular_component											owl:Class	
GO:0015810	biolink:NamedThing	aspartate transmembrane transport	The process in which aspartate is transported across a lipid bilayer, from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	mitochondrial aspartate/glutamate transport|aspartate transport													biological_process											owl:Class	
GO:1901965	biolink:NamedThing	endoplasmic reticulum to chloroplast transport	The directed movement of substances from endoplasmic reticulum to chloroplast.	tmpzr1t_l9r_go_relaxed.owl	ER to chloroplast transport							tb	2013-02-20T23:48:52Z					biological_process											owl:Class	
GO:0010890	biolink:NamedThing	positive regulation of sequestering of triglyceride	Any process that increases the rate, frequency or extent of sequestering of triglyceride. Triglyceride sequestration is the process of binding or confining any triester of glycerol such that it is separated from other components of a biological system.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of triglyceride sequestration|positive regulation of sequestering of triacylglycerol													biological_process											owl:Class	
GO:1902443	biolink:NamedThing	negative regulation of ripoptosome assembly involved in necroptotic process	Any process that stops, prevents or reduces the frequency, rate or extent of ripoptosome assembly involved in a necroptotic process.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of ripoptosome assembly involved in necroptosis|down-regulation of ripoptosome assembly involved in necroptosis|down regulation of ripoptosome assembly involved in necroptosis|downregulation of ripoptosome assembly involved in necroptosis|inhibition of ripoptosome assembly involved in necroptosis							dph	2013-10-10T17:51:41Z					biological_process											owl:Class	
GO:0001893	biolink:NamedThing	maternal placenta development	Maternally driven process whose specific outcome is the progression of the placenta over time, from its formation to the mature structure. The placenta is an organ of metabolic interchange between fetus and mother, partly of embryonic origin and partly of maternal origin.	tmpzr1t_l9r_go_relaxed.owl	decidua development													biological_process											owl:Class	
GO:0045026	biolink:NamedThing	plasma membrane fusion	The joining of the lipid bilayer membrane that surround a cell with that of another cell, producing a single cell.	tmpzr1t_l9r_go_relaxed.owl	cell fusion|cell-cell fusion											GO:0006947		biological_process											owl:Class	
GO:0007009	biolink:NamedThing	plasma membrane organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the plasma membrane.	tmpzr1t_l9r_go_relaxed.owl	plasma membrane organization and biogenesis|plasma membrane organisation													biological_process											owl:Class	
GO:0071661	biolink:NamedThing	regulation of granzyme B production	Any process that modulates the frequency, rate, or extent of production of granzyme B.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-02-12T10:41:14Z					biological_process											owl:Class	
GO:0033935	biolink:NamedThing	oligoxyloglucan beta-glycosidase activity	Catalysis of the hydrolysis of (1->4)-beta-D-glucosidic links in oligoxyloglucans so as to remove successive isoprimeverose (i.e. alpha-xylo-1,6-beta-D-glucosyl-) residues from the non-reducing chain ends.	tmpzr1t_l9r_go_relaxed.owl	oligoxyloglucan xyloglucohydrolase activity|oligoxyloglucan hydrolase activity|isoprimeverose-producing oligoxyloglucan hydrolase activity				MetaCyc:3.2.1.120-RXN|EC:3.2.1.120									molecular_function											owl:Class	
GO:0090246	biolink:NamedThing	convergent extension involved in somitogenesis	The morphogenetic process in which a presomitic mesoderm narrows along the left-right axis and lengthens in the rostral-caudal axis contributing to somitogenesis.	tmpzr1t_l9r_go_relaxed.owl								tb	2010-01-22T10:59:06Z					biological_process											owl:Class	
GO:0060026	biolink:NamedThing	convergent extension	The morphogenetic process in which an epithelium narrows along one axis and lengthens in a perpendicular axis.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Convergent_extension									biological_process											owl:Class	
GO:0045970	biolink:NamedThing	negative regulation of juvenile hormone catabolic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of juvenile hormone.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of juvenile hormone degradation|down-regulation of juvenile hormone catabolic process|down regulation of juvenile hormone catabolic process|downregulation of juvenile hormone catabolic process|negative regulation of juvenile hormone catabolism|inhibition of juvenile hormone catabolic process|negative regulation of juvenile hormone breakdown													biological_process											owl:Class	
GO:1900568	biolink:NamedThing	chanoclavine-I aldehyde catabolic process	The chemical reactions and pathways resulting in the breakdown of chanoclavine-I aldehyde.	tmpzr1t_l9r_go_relaxed.owl	chanoclavine-I aldehyde breakdown|chanoclavine-I aldehyde catabolism|chanoclavine-I aldehyde degradation							di	2012-05-15T06:31:21Z					biological_process											owl:Class	
GO:0004631	biolink:NamedThing	phosphomevalonate kinase activity	Catalysis of the reaction: (R)-5-phosphomevalonate + ATP = (R)-5-diphosphomevalonate + ADP + H(+).	tmpzr1t_l9r_go_relaxed.owl	5-phosphomevalonate kinase activity|mevalonate phosphate kinase activity|ATP:5-phosphomevalonate phosphotransferase activity|ATP:(R)-5-phosphomevalonate phosphotransferase activity|mevalonic acid phosphate kinase activity|mevalonate-5-phosphate kinase activity				MetaCyc:PHOSPHOMEVALONATE-KINASE-RXN|KEGG_REACTION:R03245|EC:2.7.4.2|Reactome:R-HSA-191422|RHEA:16341									molecular_function											owl:Class	
GO:1902942	biolink:NamedThing	negative regulation of voltage-gated chloride channel activity	Any process that stops, prevents or reduces the frequency, rate or extent of voltage-gated chloride channel activity.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of voltage gated chloride channel activity|down regulation of voltage-gated chloride channel activity|downregulation of voltage gated chloride channel activity|negative regulation of voltage-dependent chloride channel activity|downregulation of voltage-dependent chloride channel activity|inhibition of voltage-dependent chloride channel activity|down regulation of voltage-dependent chloride channel activity|inhibition of voltage-gated chloride channel activity|inhibition of voltage gated chloride channel activity|downregulation of voltage-gated chloride channel activity|down-regulation of voltage-gated chloride channel activity|down regulation of voltage gated chloride channel activity|negative regulation of voltage gated chloride channel activity|down-regulation of voltage-dependent chloride channel activity							als	2014-04-28T08:55:37Z					biological_process											owl:Class	
GO:1903796	biolink:NamedThing	negative regulation of inorganic anion transmembrane transport	Any process that stops, prevents or reduces the frequency, rate or extent of inorganic anion transmembrane transport.	tmpzr1t_l9r_go_relaxed.owl	downregulation of transmembrane inorganic anion transport|down regulation of inorganic anion membrane transport|inhibition of transmembrane inorganic anion transport|negative regulation of inorganic anion membrane transport|inhibition of inorganic anion membrane transport|negative regulation of transmembrane inorganic anion transport|downregulation of inorganic anion transmembrane transport|downregulation of inorganic anion membrane transport|down regulation of inorganic anion transmembrane transport|down regulation of transmembrane inorganic anion transport|inhibition of inorganic anion transmembrane transport|down-regulation of transmembrane inorganic anion transport|down-regulation of inorganic anion membrane transport|down-regulation of inorganic anion transmembrane transport							sl	2015-01-14T21:44:59Z					biological_process											owl:Class	
GO:1903211	biolink:NamedThing	mitotic recombination involved in replication fork processing	Any mitotic recombination that is involved in replication fork processing.	tmpzr1t_l9r_go_relaxed.owl	mitotic recombination involved in replication fork restart|mitotic recombination involved in replication restart|mitotic recombination involved in collapsed replication fork processing|mitotic recombination involved in recovery from replication fork stalling|mitotic recombination involved in recovery from replication fork arrest							mah	2014-07-24T09:33:40Z					biological_process											owl:Class	
GO:0006312	biolink:NamedThing	mitotic recombination	The exchange, reciprocal or nonreciprocal, of genetic material between one DNA molecule and a homologous DNA region that occurs during mitotic cell cycles.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Mitotic_crossover									biological_process											owl:Class	
GO:0051648	biolink:NamedThing	vesicle localization	Any process in which a vesicle or vesicles are transported to, and/or maintained in, a specific location.	tmpzr1t_l9r_go_relaxed.owl	establishment and maintenance of vesicle localization|cytoplasmic vesicle localization|vesicle localisation													biological_process											owl:Class	
GO:0019855	biolink:NamedThing	calcium channel inhibitor activity	Binds to and stops, prevents, or reduces the activity of a calcium channel.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0005246	biolink:NamedThing	calcium channel regulator activity	Modulates the activity of a calcium channel.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0000967	biolink:NamedThing	rRNA 5'-end processing	Any process involved in forming the mature 5' end of an rRNA molecule.	tmpzr1t_l9r_go_relaxed.owl	rRNA 5' end processing													biological_process											owl:Class	
GO:0033019	biolink:NamedThing	5-hydroxyvalerate dehydrogenase activity	Catalysis of the reaction: 5-hydroxyvalerate + NAD+ = 5-oxovalerate + NADH.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1990177	biolink:NamedThing	IHF-DNA complex	A protein-DNA complex containing IHF heterodimers (an alpha and a beta chain) bound to DNA. IHF binds to double-stranded DNA in a structure- and sequence-specific manner and bends the DNA into a nucleosome-like structure, the bacterial nucleoid.	tmpzr1t_l9r_go_relaxed.owl	IHFa-IHFb-DNA complex|IHF complex							bhm	2013-08-30T12:22:54Z					cellular_component											owl:Class	
GO:1990104	biolink:NamedThing	DNA bending complex	A protein-DNA complex that contains DNA in combination with a protein which binds to and bends DNA. Often plays a role in DNA compaction.	tmpzr1t_l9r_go_relaxed.owl	histone-like DNA binding complex							bhm	2013-05-20T09:29:06Z					cellular_component											owl:Class	
GO:0017162	biolink:NamedThing	aryl hydrocarbon receptor binding	Binding to an aryl hydrocarbon receptor.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:2000788	biolink:NamedThing	negative regulation of venous endothelial cell fate commitment	Any process that stops, prevents or reduces the frequency, rate or extent of venous endothelial cell fate commitment.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-06-24T01:26:16Z					biological_process											owl:Class	
GO:2000787	biolink:NamedThing	regulation of venous endothelial cell fate commitment	Any process that modulates the frequency, rate or extent of venous endothelial cell fate commitment.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-06-24T01:26:12Z					biological_process											owl:Class	
GO:0045955	biolink:NamedThing	negative regulation of calcium ion-dependent exocytosis	Any process that stops, prevents, or reduces the frequency, rate or extent of calcium ion-dependent exocytosis.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of calcium ion-dependent exocytosis|inhibition of calcium ion-dependent exocytosis|down regulation of calcium ion-dependent exocytosis|downregulation of calcium ion-dependent exocytosis													biological_process											owl:Class	
GO:1903306	biolink:NamedThing	negative regulation of regulated secretory pathway	Any process that stops, prevents or reduces the frequency, rate or extent of regulated secretory pathway.	tmpzr1t_l9r_go_relaxed.owl	inhibition of regulated secretory pathway|down regulation of regulated secretory pathway|down-regulation of regulated secretory pathway|downregulation of regulated secretory pathway					An example of this is protein domain-specific expression of Synaptotagmin 1 in rat (P21707) in PMID:12526776 inferred from mutant phenotype.		pad	2014-08-18T10:05:02Z					biological_process											owl:Class	
GO:1904305	biolink:NamedThing	negative regulation of gastro-intestinal system smooth muscle contraction	Any process that stops, prevents or reduces the frequency, rate or extent of gastro-intestinal system smooth muscle contraction.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of gastro-intestinal system smooth muscle contraction|inhibition of gastro-intestinal system smooth muscle contraction|down regulation of gastro-intestinal system smooth muscle contraction|downregulation of gastro-intestinal system smooth muscle contraction							sl	2015-06-09T23:18:48Z					biological_process											owl:Class	
GO:1904304	biolink:NamedThing	regulation of gastro-intestinal system smooth muscle contraction	Any process that modulates the frequency, rate or extent of gastro-intestinal system smooth muscle contraction.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-06-09T23:18:42Z					biological_process											owl:Class	
GO:0070917	biolink:NamedThing	inositol phosphoceramide synthase regulator activity	Binds to and modulates the activity of inositol phosphoceramide synthase.	tmpzr1t_l9r_go_relaxed.owl	IPC synthase regulator activity					See also the molecular function term 'histone acetyltransferase activity ; GO:0004402'.		mah	2009-09-10T05:27:06Z					molecular_function											owl:Class	
GO:0034668	biolink:NamedThing	integrin alpha4-beta1 complex	An integrin complex that comprises one alpha4 subunit and one beta1 subunit.	tmpzr1t_l9r_go_relaxed.owl	ITGA4-ITGB1 complex|alpha4-beta1 integrin complex|VLA-4 complex													cellular_component											owl:Class	
GO:0050239	biolink:NamedThing	pyrithiamine deaminase activity	Catalysis of the reaction: 1-(4-amino-2-methylpyrimid-5-ylmethyl)-3-(beta-hydroxyethyl)-2-methylpyridinium bromide + H2O = 1-(4-hydroxy-2-methylpyrimid-5-ylmethyl)-3-(beta-hydroxyethyl)-2-methylpyridinium bromide + NH3.	tmpzr1t_l9r_go_relaxed.owl	1-(4-amino-2-methylpyrimid-5-ylmethyl)-3-(beta-hydroxyethyl)-2-methylpyridinium-bromide aminohydrolase activity				RHEA:14537|EC:3.5.4.20|MetaCyc:PYRITHIAMIN-DEAMINASE-RXN									molecular_function											owl:Class	
GO:0019239	biolink:NamedThing	deaminase activity	Catalysis of the removal of an amino group from a substrate, producing a substituted or nonsubstituted ammonia (NH3/NH2R).	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-9014641									molecular_function											owl:Class	
GO:0002785	biolink:NamedThing	negative regulation of antimicrobial peptide production	Any process that stops, prevents, or reduces the frequency, rate, or extent of antimicrobial peptide production.	tmpzr1t_l9r_go_relaxed.owl	inhibition of antimicrobial peptide production|down regulation of antimicrobial peptide production|downregulation of antimicrobial peptide production|down-regulation of antimicrobial peptide production													biological_process											owl:Class	
GO:0002784	biolink:NamedThing	regulation of antimicrobial peptide production	Any process that modulates the frequency, rate, or extent of antimicrobial peptide production.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1903387	biolink:NamedThing	positive regulation of homophilic cell adhesion	Any process that activates or increases the frequency, rate or extent of homophilic cell adhesion.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of homophilic cell adhesion|activation of homophilic cell adhesion|upregulation of homophilic cell adhesion|up regulation of homophilic cell adhesion							als	2014-08-27T09:57:46Z					biological_process											owl:Class	
GO:1903385	biolink:NamedThing	regulation of homophilic cell adhesion	Any process that modulates the frequency, rate or extent of homophilic cell adhesion.	tmpzr1t_l9r_go_relaxed.owl								als	2014-08-27T09:57:30Z					biological_process											owl:Class	
GO:1904452	biolink:NamedThing	negative regulation of potassium:proton exchanging ATPase activity	Any process that stops, prevents or reduces the frequency, rate or extent of hydrogen:potassium-exchanging ATPase activity.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of (K+ + H+)-ATPase activity|negative regulation of H+/K+-ATPase activity|down-regulation of gastric H(+)/K(+) ATPase activity|negative regulation of hydrogen:potassium exchanging ATPase activity|negative regulation of H+/K+-exchanging ATPase activity|negative regulation of H,K-ATPase activity|down regulation of gastric H(+)/K(+) ATPase activity|down regulation of hydrogen:potassium-exchanging ATPase activity|down regulation of H+/K+-ATPase activity|down regulation of H,K-ATPase activity|inhibition of hydrogen:potassium-exchanging ATPase activity|downregulation of H+-K+-ATPase activity|down regulation of H+-K+-ATPase activity|inhibition of H(+)/K(+)-ATPase activity|down regulation of H+/K+-exchanging ATPase activity|downregulation of H,K-ATPase activity|inhibition of H+/K+-ATPase activity|down-regulation of H+/K+-ATPase activity|down-regulation of H(+)/K(+)-exchanging ATPase activity|downregulation of gastric H(+)/K(+) ATPase activity|down regulation of (K+ + H+)-ATPase activity|downregulation of (K+ + H+)-ATPase activity|inhibition of ATP phosphohydrolase (H+/K+-exchanging)|downregulation of H+/K+-exchanging ATPase activity|downregulation of hydrogen/potassium-exchanging ATPase activity|inhibition of H,K-ATPase activity|down regulation of hydrogen/potassium-exchanging ATPase activity|down regulation of gastric H+/K+ ATPase|down-regulation of H,K-ATPase activity|downregulation of H(+)/K(+)-exchanging ATPase activity|down-regulation of hydrogen:potassium exchanging ATPase activity|downregulation of ATP phosphohydrolase (H+/K+-exchanging)|down-regulation of hydrogen:potassium-exchanging ATPase activity|inhibition of gastric H(+)/K(+) ATPase activity|inhibition of hydrogen:potassium exchanging ATPase activity|down-regulation of ATP phosphohydrolase (H+/K+-exchanging)|down-regulation of gastric H+/K+ ATPase|negative regulation of (K+ + H+)-ATPase activity|down regulation of H(+)/K(+)-exchanging ATPase activity|downregulation of gastric H+/K+ ATPase|inhibition of (K+ + H+)-ATPase activity|negative regulation of hydrogen:potassium-exchanging ATPase activity|negative regulation of ATP phosphohydrolase (H+/K+-exchanging)|down-regulation of H(+)/K(+)-ATPase activity|inhibition of H+/K+-exchanging ATPase activity|negative regulation of H(+)/K(+)-ATPase activity|inhibition of hydrogen/potassium-exchanging ATPase activity|negative regulation of gastric H+/K+ ATPase|negative regulation of hydrogen/potassium-exchanging ATPase activity|down regulation of H(+)/K(+)-ATPase activity|down-regulation of H+/K+-exchanging ATPase activity|down-regulation of hydrogen/potassium-exchanging ATPase activity|inhibition of H+-K+-ATPase activity|down regulation of hydrogen:potassium exchanging ATPase activity|downregulation of H(+)/K(+)-ATPase activity|downregulation of hydrogen:potassium exchanging ATPase activity|inhibition of gastric H+/K+ ATPase|negative regulation of H(+)/K(+)-exchanging ATPase activity|down regulation of ATP phosphohydrolase (H+/K+-exchanging)|downregulation of hydrogen:potassium-exchanging ATPase activity|negative regulation of gastric H(+)/K(+) ATPase activity|down-regulation of H+-K+-ATPase activity|negative regulation of H+-K+-ATPase activity|inhibition of H(+)/K(+)-exchanging ATPase activity|downregulation of H+/K+-ATPase activity							sl	2015-07-08T23:00:09Z					biological_process											owl:Class	
GO:1904451	biolink:NamedThing	regulation of potassium:proton exchanging ATPase activity	Any process that modulates the frequency, rate or extent of hydrogen:potassium-exchanging ATPase activity.	tmpzr1t_l9r_go_relaxed.owl	regulation of H+-K+-ATPase activity|regulation of H(+)/K(+)-ATPase activity|regulation of H(+)/K(+)-exchanging ATPase activity|regulation of hydrogen:potassium exchanging ATPase activity|regulation of hydrogen:potassium-exchanging ATPase activity|regulation of gastric H(+)/K(+) ATPase activity|regulation of gastric H+/K+ ATPase|regulation of (K+ + H+)-ATPase activity|regulation of hydrogen/potassium-exchanging ATPase activity|regulation of proton pump activity|regulation of H,K-ATPase activity|regulation of H+/K+-exchanging ATPase activity|regulation of ATP phosphohydrolase (H+/K+-exchanging)|regulation of H+/K+-ATPase activity							sl	2015-07-08T23:00:03Z					biological_process											owl:Class	
GO:0043369	biolink:NamedThing	CD4-positive or CD8-positive, alpha-beta T cell lineage commitment	The process in which an immature T cell commits to CD4-positive T cell lineage or the CD8-positive lineage of alpha-beta T cells.	tmpzr1t_l9r_go_relaxed.owl	CD4-positive/CD8-positive, alpha-beta T cell lineage commitment|CD4-positive or CD8-positive, alpha-beta T-lymphocyte lineage commitment|CD4-positive or CD8-positive, alpha-beta T-cell lineage commitment|CD4-positive or CD8-positive, alpha-beta T lymphocyte lineage commitment													biological_process											owl:Class	
GO:0002360	biolink:NamedThing	T cell lineage commitment	The process in which a lymphoid progenitor cell becomes committed to becoming any type of T cell.	tmpzr1t_l9r_go_relaxed.owl	T-lymphocyte lineage commitment|T lymphocyte lineage commitment|T-cell lineage commitment													biological_process											owl:Class	
GO:0046656	biolink:NamedThing	folic acid biosynthetic process	The chemical reactions and pathways resulting in the formation of folic acid, pteroylglutamic acid.	tmpzr1t_l9r_go_relaxed.owl	vitamin B9 biosynthetic process|folic acid anabolism|vitamin M biosynthesis|folic acid biosynthesis|folic acid synthesis|vitamin B9 biosynthesis|folate biosynthesis|folic acid formation|folate biosynthetic process|vitamin M biosynthetic process				Wikipedia:Folic_acid|MetaCyc:FOLSYN-PWY									biological_process											owl:Class	
GO:0042364	biolink:NamedThing	water-soluble vitamin biosynthetic process	The chemical reactions and pathways resulting in the formation of any of a diverse group of vitamins that are soluble in water.	tmpzr1t_l9r_go_relaxed.owl	water-soluble vitamin formation|water-soluble vitamin biosynthesis|water-soluble vitamin anabolism|water-soluble vitamin synthesis													biological_process											owl:Class	
GO:0036255	biolink:NamedThing	response to methylamine	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methylamine stimulus.	tmpzr1t_l9r_go_relaxed.owl								bf	2012-06-15T01:07:27Z					biological_process											owl:Class	
GO:0014075	biolink:NamedThing	response to amine	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amine stimulus. An amine is a compound formally derived from ammonia by replacing one, two or three hydrogen atoms by hydrocarbyl groups.	tmpzr1t_l9r_go_relaxed.owl	response to amine stimulus													biological_process											owl:Class	
GO:0035107	biolink:NamedThing	appendage morphogenesis	The process in which the anatomical structures of appendages are generated and organized. An appendage is an organ or part that is attached to the trunk of an organism, such as a limb or a branch.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0018250	biolink:NamedThing	peptidyl-dehydroalanine biosynthetic process from peptidyl-tyrosine or peptidyl-serine	The formation of peptidyl-dehydroalanine from either peptidyl-tyrosine by phenyl transfer, or from peptidyl-serine, which is coupled with the formation of 5-imidazolinone by the two neighboring residues, produces an 4-methylidene-imidazole-5-one active site of some amino acid ammonia-lyases; the 4-methylidene-imidazole-5-one, is formed autocatalytically by cyclization and dehydration of the sequence ASG.	tmpzr1t_l9r_go_relaxed.owl	peptidyl-dehydroalanine anabolism from peptidyl-tyrosine or peptidyl-serine|peptidyl-dehydroalanine synthesis from peptidyl-tyrosine or peptidyl-serine|peptidyl-dehydroalanine formation from peptidyl-tyrosine or peptidyl-serine				RESID:AA0181									biological_process											owl:Class	
GO:0015712	biolink:NamedThing	hexose phosphate transport	The directed movement of hexose phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0015748	biolink:NamedThing	organophosphate ester transport	The directed movement of organophosphate esters into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Organophosphate esters are small organic molecules containing phosphate ester bonds.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0002868	biolink:NamedThing	negative regulation of B cell deletion	Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell deletion.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of B cell deletion|inhibition of B cell deletion|negative regulation of B lymphocyte deletion|negative regulation of B-cell deletion|downregulation of B cell deletion|down regulation of B cell deletion|negative regulation of B-lymphocyte deletion													biological_process											owl:Class	
GO:0044013	biolink:NamedThing	H2B histone acetyltransferase activity	Catalysis of the reaction: acetyl-CoA + histone H2B L-lysine = CoA + histone H2B N6-acetyl-L-lysine.	tmpzr1t_l9r_go_relaxed.owl	H2B histone lysine N-acetyltransferase activity													molecular_function											owl:Class	
GO:0004402	biolink:NamedThing	histone acetyltransferase activity	Catalysis of the reaction: acetyl-CoA + histone = CoA + acetyl-histone.	tmpzr1t_l9r_go_relaxed.owl	H3/H4 histone acetyltransferase activity|histone acetylase activity|histone acetokinase activity|histone transacetylase activity|acetyl-CoA:histone acetyltransferase activity|H2A/H2B histone acetyltransferase activity|H4/H2A acetyltransferase activity|histone lysine acetyltransferase activity|H4/H2 histone acetyltransferase activity|nucleosome-histone acetyltransferase activity				Reactome:R-HSA-3301345|Reactome:R-HSA-3697008|Reactome:R-HSA-3697920|MetaCyc:HISTONE-ACETYLTRANSFERASE-RXN|Reactome:R-HSA-3451147|EC:2.3.1.48|Reactome:R-HSA-3662335|Reactome:R-HSA-5250938|Reactome:R-HSA-3318413|Reactome:R-HSA-3321883|Reactome:R-HSA-3662318|RHEA:21992|Reactome:R-HSA-3321805|Reactome:R-HSA-3321975|Reactome:R-HSA-3318486|Reactome:R-HSA-3318415|Reactome:R-HSA-3301237|Reactome:R-HSA-5144542	Note that the term 'histone lysine acetyltransferase activity ; GO:0046971' was merged into this term because only lysine residues are ever acetylated in histones, and so the term was redundant.						GO:0043166|GO:0004406|GO:0046971|GO:0004404|GO:0004403|GO:0004405		molecular_function											owl:Class	
GO:0043665	biolink:NamedThing	host peribacteroid fluid	The soluble material inside the peribacteroid membrane, but outside of the bacteroid, within a bacteroid-containing symbiosome of a host cell.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0090191	biolink:NamedThing	negative regulation of branching involved in ureteric bud morphogenesis	Any process that decreases the rate, frequency or extent of branching involved in ureteric bud morphogenesis, the process in which the branching structure of the ureteric bud is generated and organized. The ureteric bud is an epithelial tube that grows out from the metanephric duct. The bud elongates and branches to give rise to the ureter and kidney collecting tubules.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-12-18T11:11:17Z					biological_process											owl:Class	
GO:0090189	biolink:NamedThing	regulation of branching involved in ureteric bud morphogenesis	Any process that modulates the rate, frequency or extent of branching involved in ureteric bud morphogenesis, the process in which the branching structure of the ureteric bud is generated and organized. The ureteric bud is an epithelial tube that grows out from the metanephric duct. The bud elongates and branches to give rise to the ureter and kidney collecting tubules.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-12-18T11:11:17Z					biological_process											owl:Class	
GO:0045141	biolink:NamedThing	meiotic telomere clustering	The cell cycle process in which the dynamic reorganization of telomeres occurs in early meiotic prophase, during which meiotic chromosome ends are gathered in a bouquet arrangement at the inner surface of the nuclear envelope proximal to the spindle pole body. This plays an important role in progression through meiosis and precedes synapsis.	tmpzr1t_l9r_go_relaxed.owl	bouquet biosynthesis|bouquet formation													biological_process											owl:Class	
GO:0090220	biolink:NamedThing	chromosome localization to nuclear envelope involved in homologous chromosome segregation	The directed movement of a chromosome to the nuclear envelope that contributes to homologous chromosome segregation and precedes synapsis.	tmpzr1t_l9r_go_relaxed.owl	chromosome localisation to nuclear envelope involved in homologous chromosome segregation							tb	2010-01-13T10:20:33Z					biological_process											owl:Class	
GO:0033400	biolink:NamedThing	trans-zeatin metabolic process	The chemical reactions and pathways involving trans-zeatin, (2E)-2-methyl-4-(9H-purin-6-ylamino)but-2-en-1-ol.	tmpzr1t_l9r_go_relaxed.owl	trans-zeatin metabolism													biological_process											owl:Class	
GO:0033397	biolink:NamedThing	zeatin metabolic process	The chemical reactions and pathways involving zeatin, 2-methyl-4-(9H-purin-6-ylamino)but-2-en-1-ol.	tmpzr1t_l9r_go_relaxed.owl	zeatin metabolism													biological_process											owl:Class	
GO:0009291	biolink:NamedThing	unidirectional conjugation	The process of unidirectional (polarized) transfer of genetic information involving direct cellular contact between a donor and recipient cell; the contact is followed by the formation of a cellular bridge that physically connects the cells; some or all of the chromosome(s) of one cell ('male') is then transferred into the other cell ('female'); unidirectional conjugation occurs between cells of different mating types. Examples of this process are found in prokaryotes.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0000746	biolink:NamedThing	conjugation	The union or introduction of genetic information from compatible mating types that results in a genetically different individual. Conjugation requires direct cellular contact between the organisms.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Conjugation									biological_process											owl:Class	
GO:0009750	biolink:NamedThing	response to fructose	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fructose stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to fructose stimulus													biological_process											owl:Class	
GO:0009746	biolink:NamedThing	response to hexose	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hexose stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to hexose stimulus													biological_process											owl:Class	
GO:1903122	biolink:NamedThing	negative regulation of TRAIL-activated apoptotic signaling pathway	Any process that stops, prevents or reduces the frequency, rate or extent of TRAIL-activated apoptotic signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	down regulation of TRAIL-activated apoptotic signaling pathway|negative regulation of TRAIL-activated extrinsic apoptotic signaling pathway|inhibition of TRAIL-activated extrinsic apoptotic signaling pathway|down-regulation of TRAIL-activated extrinsic apoptotic signaling pathway|down regulation of TRAIL-induced apoptotic signaling pathway|down-regulation of TRAIL-induced apoptotic signaling pathway|downregulation of tumor necrosis factor-related apoptosis-inducing ligand apoptotic signaling pathway|negative regulation of tumor necrosis factor-related apoptosis-inducing ligand apoptotic signaling pathway|downregulation of TRAIL-induced apoptotic signaling pathway|downregulation of TRAIL-activated extrinsic apoptotic signaling pathway|down regulation of TRAIL-activated extrinsic apoptotic signaling pathway|inhibition of TRAIL-activated apoptotic signaling pathway|inhibition of tumor necrosis factor-related apoptosis-inducing ligand apoptotic signaling pathway|inhibition of TRAIL-induced apoptotic signaling pathway|downregulation of TRAIL-activated apoptotic signaling pathway|down-regulation of tumor necrosis factor-related apoptosis-inducing ligand apoptotic signaling pathway|down regulation of tumor necrosis factor-related apoptosis-inducing ligand apoptotic signaling pathway|down-regulation of TRAIL-activated apoptotic signaling pathway|negative regulation of TRAIL-induced apoptotic signaling pathway							bf	2014-06-17T12:39:21Z					biological_process											owl:Class	
GO:0050862	biolink:NamedThing	positive regulation of T cell receptor signaling pathway	Any process that activates or increases the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a T cell.	tmpzr1t_l9r_go_relaxed.owl	upregulation of T cell receptor signaling pathway|positive regulation of T cell receptor signalling pathway|activation of T cell receptor signaling pathway|positive regulation of T-lymphocyte receptor signaling pathway|positive regulation of T lymphocyte receptor signaling pathway|positive regulation of T-cell receptor signaling pathway|positive regulation of T-lymphocyte receptor signalling pathway|positive regulation of TCR signaling pathway|positive regulation of T lymphocyte receptor signalling pathway|stimulation of T cell receptor signaling pathway|up regulation of T cell receptor signaling pathway|up-regulation of T cell receptor signaling pathway													biological_process											owl:Class	
GO:0050856	biolink:NamedThing	regulation of T cell receptor signaling pathway	Any process that modulates the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a T cell.	tmpzr1t_l9r_go_relaxed.owl	regulation of T lymphocyte receptor signaling pathway|regulation of T-lymphocyte receptor signalling pathway|regulation of T-cell receptor signalling pathway|regulation of TCR signaling pathway|regulation of T-cell receptor signaling pathway|regulation of T-lymphocyte receptor signaling pathway|regulation of T lymphocyte receptor signalling pathway													biological_process											owl:Class	
GO:0060562	biolink:NamedThing	epithelial tube morphogenesis	The process in which the anatomical structures of a tube are generated and organized from an epithelium. Epithelial tubes transport gases, liquids and cells from one site to another and form the basic structure of many organs and tissues, with tube shape and organization varying from the single-celled excretory organ in Caenorhabditis elegans to the branching trees of the mammalian kidney and insect tracheal system.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-04-28T09:33:36Z					biological_process											owl:Class	
GO:0035239	biolink:NamedThing	tube morphogenesis	The process in which the anatomical structures of a tube are generated and organized. Epithelial and endothelial tubes transport gases, liquids and cells from one site to another and form the basic structure of many organs and tissues, with tube shape and organization varying from the single-celled excretory organ in Caenorhabditis elegans to the branching trees of the mammalian kidney and insect tracheal system.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0006629	biolink:NamedThing	lipid metabolic process	The chemical reactions and pathways involving lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. Includes fatty acids; neutral fats, other fatty-acid esters, and soaps; long-chain (fatty) alcohols and waxes; sphingoids and other long-chain bases; glycolipids, phospholipids and sphingolipids; and carotenes, polyprenols, sterols, terpenes and other isoprenoids.	tmpzr1t_l9r_go_relaxed.owl	lipid metabolism				Wikipedia:Lipid_metabolism									biological_process											owl:Class	
GO:0044238	biolink:NamedThing	primary metabolic process	The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism.	tmpzr1t_l9r_go_relaxed.owl	primary metabolism													biological_process											owl:Class	
GO:0090625	biolink:NamedThing	mRNA destabilization-mediated gene silencing by siRNA	The process in which small interfering RNAs (siRNAs) direct the cleavage of target mRNAs. Once incorporated into a RNA-induced silencing complex (RISC), a siRNA will typically direct cleavage by base pairing with perfect or near-perfect complementarity to the target mRNA.	tmpzr1t_l9r_go_relaxed.owl	mRNA cleavage involved in gene silencing by siRNA	https://github.com/geneontology/go-ontology/issues/22389						tb	2015-01-21T17:15:13Z					biological_process											owl:Class	
GO:0035194	biolink:NamedThing	post-transcriptional gene silencing by RNA	Any process of posttranscriptional gene inactivation (silencing) mediated by small RNA molecules that may trigger RNA (often mRNA) degradation or negatively regulate mRNA translation.	tmpzr1t_l9r_go_relaxed.owl	RNA-mediated posttranscriptional gene silencing|sense-PTGS|posttranscriptional gene silencing by RNA													biological_process											owl:Class	
GO:0033949	biolink:NamedThing	fructan beta-(2,6)-fructosidase activity	Catalysis of the hydrolysis of terminal, non-reducing (2->6) linked beta-D-fructofuranose residues in fructans.	tmpzr1t_l9r_go_relaxed.owl	beta-(2,6)-fructan exohydrolase activity|6-FEH|beta-(2,6)-D-fructan fructohydrolase activity				EC:3.2.1.154|MetaCyc:3.2.1.154-RXN									molecular_function											owl:Class	
GO:0035367	biolink:NamedThing	positive regulation of thymine transport	Any process that activates or increases the frequency, rate or extent of the directed movement of thymine, 5-methyluracil, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of 5-methyluracil transport							bf	2010-03-11T10:24:25Z					biological_process											owl:Class	
GO:0072558	biolink:NamedThing	NLRP1 inflammasome complex	An inflammasome complex that consists of two components, NLRP1 (NALP1) and caspase-1 or caspase-5. The exact mechanisms of NLRP1 activation remain obscure, but potassium ion efflux appears to be essential.	tmpzr1t_l9r_go_relaxed.owl	NALP1 inflammasome complex							mah	2011-01-27T12:03:50Z					cellular_component											owl:Class	
GO:0061702	biolink:NamedThing	inflammasome complex	A cytosolic protein complex that is capable of activating caspase-1.	tmpzr1t_l9r_go_relaxed.owl								dph	2015-05-08T14:30:54Z					cellular_component											owl:Class	
GO:0035565	biolink:NamedThing	regulation of pronephros size	Any process that modulates the size of a pronephric kidney.	tmpzr1t_l9r_go_relaxed.owl	regulation of pronephric kidney size							bf	2010-07-23T11:28:57Z					biological_process											owl:Class	
GO:0035564	biolink:NamedThing	regulation of kidney size	Any process that modulates the size of a kidney.	tmpzr1t_l9r_go_relaxed.owl								bf	2010-07-23T11:28:22Z					biological_process											owl:Class	
GO:0008508	biolink:NamedThing	bile acid:sodium symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: bile acid(out) + Na+(out) = bile acid(in) + Na+(in).	tmpzr1t_l9r_go_relaxed.owl	sodium/bile acid symporter activity				Reactome:R-HSA-194187|Reactome:R-HSA-433089|Reactome:R-HSA-194121									molecular_function											owl:Class	
GO:0034050	biolink:NamedThing	programmed cell death induced by symbiont	Cell death resulting from activation of endogenous cellular processes after interaction with a symbiont (defined as the smaller of two, or more, organisms engaged in symbiosis, a close interaction encompassing mutualism through parasitism). This can be triggered by direct interaction with the organism, for example, contact with penetrating hyphae of a fungus; or an indirect interaction such as symbiont-secreted molecules.	tmpzr1t_l9r_go_relaxed.owl	'host programmed cell death induced by symbiont'	https://github.com/geneontology/go-ontology/issues/20255				Note that this term is to be used to annotate gene products in the host, not the symbiont. To annotate gene products in the symbiont that induce programmed cell death in the host, consider the biological process term 'positive regulation by symbiont of host programmed cell death ; GO:0052042'.								biological_process											owl:Class	
GO:0051702	biolink:NamedThing	biological process involved in interaction with symbiont	An interaction between two organisms living together in more or less intimate association. The term symbiont is used for the smaller (macro) of the two members of a symbiosis; the various forms of symbiosis include parasitism, commensalism and mutualism.	tmpzr1t_l9r_go_relaxed.owl	interaction with symbiont	https://github.com/geneontology/go-ontology/issues/20191												biological_process											owl:Class	
GO:0044656	biolink:NamedThing	regulation of post-lysosomal vacuole size	Any process that modulates the volume of a post-lysosomal vacuole, a membrane-bounded intracellular vesicle formed late in the endocytic pathway when the pH in the vacuole becomes neutral prior to exocytosis.	tmpzr1t_l9r_go_relaxed.owl	regulation of postlysosome vacuole size|regulation of postlysosomal vacuole size|regulation of post-lysosome size							jl	2012-07-26T04:30:56Z					biological_process											owl:Class	
GO:0032535	biolink:NamedThing	regulation of cellular component size	A process that modulates the size of a cellular component.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0071812	biolink:NamedThing	positive regulation of fever generation by positive regulation of prostaglandin secretion	Any process that increases the rate or extent of fever generation via positive regulation of the frequency, rate or extent of the regulated release of a prostaglandin from a cell.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-09-03T05:10:36Z					biological_process											owl:Class	
GO:0032308	biolink:NamedThing	positive regulation of prostaglandin secretion	Any process that activates or increases the frequency, rate or extent of the regulated release of a prostaglandin from a cell.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of prostacyclin secretion|up-regulation of prostaglandin secretion|upregulation of prostaglandin secretion|up regulation of prostaglandin secretion|activation of prostaglandin secretion|stimulation of prostaglandin secretion													biological_process											owl:Class	
GO:1901189	biolink:NamedThing	positive regulation of ephrin receptor signaling pathway	Any process that activates or increases the frequency, rate or extent of ephrin receptor signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of Eph receptor signaling pathway|up-regulation of Eph receptor signalling pathway|up-regulation of Eph receptor signaling pathway|activation of ephrin receptor signaling pathway|upregulation of Eph receptor signalling pathway|activation of Eph receptor signaling pathway|activation of Eph receptor signalling pathway|positive regulation of Eph receptor signalling pathway|up regulation of Eph receptor signaling pathway|upregulation of ephrin receptor signaling pathway|upregulation of Eph receptor signaling pathway|up regulation of ephrin receptor signaling pathway|up regulation of Eph receptor signalling pathway|up-regulation of ephrin receptor signaling pathway							rl	2012-07-24T07:42:21Z					biological_process											owl:Class	
GO:0009967	biolink:NamedThing	positive regulation of signal transduction	Any process that activates or increases the frequency, rate or extent of signal transduction.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of signal transduction|stimulation of signal transduction|up regulation of signal transduction|upregulation of signal transduction|activation of signal transduction|positive regulation of signalling pathway|positive regulation of signaling pathway											GO:0035468		biological_process											owl:Class	
GO:2001287	biolink:NamedThing	negative regulation of caveolin-mediated endocytosis	Any process that stops, prevents or reduces the frequency, rate or extent of caveolin-mediated endocytosis.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of caveolae-mediated endocytosis|negative regulation of caveolin-dependent endocytosis|negative regulation of caveolae-dependent endocytosis							yaf	2011-12-15T04:13:27Z					biological_process											owl:Class	
GO:0048248	biolink:NamedThing	CXCR3 chemokine receptor binding	Binding to a CXCR3 chemokine receptor.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0010325	biolink:NamedThing	raffinose family oligosaccharide biosynthetic process	The chemical reactions and pathways resulting in the formation of raffinose family oligosaccharides (RFOs, such as raffinose, stachyose, verbascose and other molecules with a higher degree of galactosyl polymerization).	tmpzr1t_l9r_go_relaxed.owl	raffinose family oligosaccharide biosynthesis													biological_process											owl:Class	
GO:0009312	biolink:NamedThing	oligosaccharide biosynthetic process	The chemical reactions and pathways resulting in the formation of oligosaccharides, molecules with between two and (about) 20 monosaccharide residues connected by glycosidic linkages.	tmpzr1t_l9r_go_relaxed.owl	oligosaccharide anabolism|oligosaccharide biosynthesis|oligosaccharide synthesis|oligosaccharide formation													biological_process											owl:Class	
GO:0046534	biolink:NamedThing	positive regulation of photoreceptor cell differentiation	Any process that activates or increases the frequency, rate or extent of photoreceptor cell differentiation. An example of this process is found in Drosophila melanogaster.	tmpzr1t_l9r_go_relaxed.owl	upregulation of photoreceptor cell differentiation|stimulation of photoreceptor differentiation|positive regulation of photoreceptor differentiation|stimulation of photoreceptor cell differentiation|activation of photoreceptor cell differentiation|up-regulation of photoreceptor differentiation|activation of photoreceptor differentiation|upregulation of photoreceptor differentiation|up regulation of photoreceptor differentiation|up-regulation of photoreceptor cell differentiation|up regulation of photoreceptor cell differentiation											GO:0045675		biological_process											owl:Class	
GO:1990051	biolink:NamedThing	activation of protein kinase C activity	Any process that initiates the activity of the inactive enzyme protein kinase C.	tmpzr1t_l9r_go_relaxed.owl	PKC activation|protein kinase C activation							sl	2013-02-21T19:57:54Z					biological_process											owl:Class	
GO:0021576	biolink:NamedThing	hindbrain formation	The process that gives rise to the hindbrain. This process pertains to the initial formation of a structure from unspecified parts. The hindbrain is the region consisting of the medulla, pons and cerebellum. Areas of the hindbrain control motor and autonomic functions.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0000076	biolink:NamedThing	DNA replication checkpoint signaling	A signal transduction process that contributes to a DNA replication checkpoint, that prevents the initiation of nuclear division until DNA replication is complete, thereby ensuring that progeny inherit a full complement of the genome.	tmpzr1t_l9r_go_relaxed.owl	DNA replication checkpoint|signal transduction involved in DNA replication checkpoint	https://github.com/geneontology/go-ontology/issues/20935										GO:0072437		biological_process											owl:Class	
GO:0031570	biolink:NamedThing	DNA integrity checkpoint signaling	A signaling process that controls cell cycle progression in response to changes in DNA structure by monitoring the integrity of the DNA. The DNA integrity checkpoint begins with detection of DNA damage, defects in DNA structure or DNA replication, and progresses through signal transduction and ends with cell cycle effector processes.	tmpzr1t_l9r_go_relaxed.owl	signal transduction involved in DNA integrity checkpoint|DNA integrity checkpoint	https://github.com/geneontology/go-ontology/issues/20935										GO:0072401		biological_process											owl:Class	
GO:0080142	biolink:NamedThing	regulation of salicylic acid biosynthetic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of salicylic acid.	tmpzr1t_l9r_go_relaxed.owl								dhl	2009-05-19T04:38:23Z					biological_process											owl:Class	
GO:0010337	biolink:NamedThing	regulation of salicylic acid metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving salicylic acid.	tmpzr1t_l9r_go_relaxed.owl	regulation of salicylic acid metabolism													biological_process											owl:Class	
GO:0071911	biolink:NamedThing	synchronous neurotransmitter secretion	Release of neurotransmitter at the synapse that lasts for just a few milliseconds after action potential invasion.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-09-22T01:38:36Z					biological_process											owl:Class	
GO:0045468	biolink:NamedThing	regulation of R8 cell spacing in compound eye	Any process that ensures that the R8 cells are selected in a precise progressive pattern so that they are evenly spaced throughout the eye disc.	tmpzr1t_l9r_go_relaxed.owl	R8 cell spacing in compound eye|regulation of R8 spacing													biological_process											owl:Class	
GO:0007389	biolink:NamedThing	pattern specification process	Any developmental process that results in the creation of defined areas or spaces within an organism to which cells respond and eventually are instructed to differentiate.	tmpzr1t_l9r_go_relaxed.owl	pattern formation|pattern biosynthesis													biological_process											owl:Class	
GO:0032972	biolink:NamedThing	regulation of muscle filament sliding speed	Any process that modulates the velocity of muscle filament sliding.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1904385	biolink:NamedThing	cellular response to angiotensin	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an angiotensin stimulus. Angiotensin is any of three physiologically active peptides (angiotensin II, III, or IV) processed from angiotensinogen.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-06-23T17:27:14Z					biological_process											owl:Class	
GO:0050017	biolink:NamedThing	L-3-cyanoalanine synthase activity	Catalysis of the reaction: L-cysteine + HCN = sulfide + L-3-cyanoalanine.	tmpzr1t_l9r_go_relaxed.owl	beta-cyanoalanine synthetase activity|L-cysteine hydrogen-sulfide-lyase (adding hydrogen cyanide; L-3-cyanoalanine-forming)|beta-cyano-L-alanine synthase activity|L-cysteine hydrogen-sulfide-lyase (adding HCN)|beta-cyanoalanine synthase activity				RHEA:17821|MetaCyc:L-3-CYANOALANINE-SYNTHASE-RXN|EC:4.4.1.9									molecular_function											owl:Class	
GO:1903831	biolink:NamedThing	signal transduction involved in cellular response to ammonium ion	Any signal transduction that is involved in cellular response to ammonium ion.	tmpzr1t_l9r_go_relaxed.owl	signalling cascade involved in cellular response to ammonium ion|signaling pathway involved in cellular response to ammonium ion|signalling pathway involved in cellular response to ammonium ion|signaling cascade involved in cellular response to ammonium ion							al	2015-01-21T17:52:09Z					biological_process											owl:Class	
GO:0052698	biolink:NamedThing	ergothioneine metabolic process	The chemical reactions and pathways involving ergothioneine, a naturally occurring metabolite of histidine with antioxidant properties.	tmpzr1t_l9r_go_relaxed.owl	2-mercaptoergothioneine trimethylbetaine metabolism|(2S)-3-(2-mercapto-1H-imidazol-5-yl)-2-(trimethylazaniumyl)propanoate metabolic process|ergothioneine metabolism|2-mercaptoergothioneine trimethylbetaine metabolic process							ai	2011-08-01T03:52:11Z					biological_process											owl:Class	
GO:0072716	biolink:NamedThing	response to actinomycin D	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an actinomycin D stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2012-04-26T02:06:40Z					biological_process											owl:Class	
GO:0046677	biolink:NamedThing	response to antibiotic	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antibiotic stimulus. An antibiotic is a chemical substance produced by a microorganism which has the capacity to inhibit the growth of or to kill other microorganisms.	tmpzr1t_l9r_go_relaxed.owl	antibiotic susceptibility/resistance													biological_process											owl:Class	
GO:0039613	biolink:NamedThing	suppression by virus of host protein phosphorylation	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of phosphorylation of viral or host proteins in a host.	tmpzr1t_l9r_go_relaxed.owl	viral inhibition of host protein phosphorylation							bf	2012-07-06T11:15:56Z					biological_process											owl:Class	
GO:0039612	biolink:NamedThing	modulation by virus of host protein phosphorylation	Any viral process that modulates the frequency, rate or extent of phosphorylation of viral or host proteins in a host.	tmpzr1t_l9r_go_relaxed.owl								bf	2012-07-06T11:13:59Z					biological_process											owl:Class	
GO:1904229	biolink:NamedThing	regulation of succinate dehydrogenase activity	Any process that modulates the frequency, rate or extent of succinate dehydrogenase activity.	tmpzr1t_l9r_go_relaxed.owl	regulation of succinodehydrogenase activity|regulation of fumarate dehydrogenase activity|regulation of succinate:(acceptor) oxidoreductase activity|regulation of succinate:acceptor oxidoreductase activity|regulation of succinyl dehydrogenase activity|regulation of succinic acid dehydrogenase activity|regulation of fumarate reductase activity|regulation of succinic dehydrogenase activity|regulation of succinate oxidoreductase activity|regulation of fumaric hydrogenase activity							rl	2015-05-15T09:51:08Z					biological_process											owl:Class	
GO:1901284	biolink:NamedThing	5,6,7,8-tetrahydromethanopterin catabolic process	The chemical reactions and pathways resulting in the breakdown of 5,6,7,8-tetrahydromethanopterin.	tmpzr1t_l9r_go_relaxed.owl	5,6,7,8-tetrahydromethanopterin catabolism|5,6,7,8-tetrahydromethanopterin degradation|5,6,7,8-tetrahydromethanopterin breakdown							yaf	2012-08-17T15:32:54Z					biological_process											owl:Class	
GO:0043649	biolink:NamedThing	dicarboxylic acid catabolic process	The chemical reactions and pathways resulting in the breakdown of dicarboxylic acids, any organic acid containing two carboxyl (-COOH) groups.	tmpzr1t_l9r_go_relaxed.owl	dicarboxylate catabolism|dicarboxylic acid degradation|dicarboxylic acid breakdown|dicarboxylic acid catabolism|dicarboxylate catabolic process													biological_process											owl:Class	
GO:0005591	biolink:NamedThing	collagen type VIII trimer	A collagen heterotrimer containing type VIII alpha chains; [alpha1(VIII)2]alpha2(VIII) and alpha1(VIII)[alpha2(VIII)]2 trimers have been observed; type VIII collagen triple helices associate to form regular hexagonal nets.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0030935	biolink:NamedThing	sheet-forming collagen trimer	A protein complex consisting of three collagen chains assembled into a left-handed triple helix. These trimers assemble into a sheet.	tmpzr1t_l9r_go_relaxed.owl	hexagonal network-forming collagen													cellular_component											owl:Class	
GO:0036410	biolink:NamedThing	Mst2 histone acetyltransferase complex	A protein complex that can catalyze the acetylation of lysine at position 14 in histone H3, and contains Mst2 as the catalytic subunit. In fission yeast, contains at least Mst2, Nto1, Ptf2, Ptf1 and Eaf6.	tmpzr1t_l9r_go_relaxed.owl	Mst2 histone H3K14 acetyltransferase complex|Mst2 H3K14 acetyltransferase complex|Mst2 complex							bf	2013-08-21T10:11:32Z					cellular_component											owl:Class	
GO:0036409	biolink:NamedThing	histone H3-K14 acetyltransferase complex	A protein complex that can catalyze the acetylation of lysine at position 14 in histone H3.	tmpzr1t_l9r_go_relaxed.owl	histone H3 Lys 14 (H3K14) acetyltransferase complex|H3-K14 histone acetyltransferase complex|histone acetyltransferase complex (H3-K14 specific)|histone H3K14 acetyltransferase complex							bf	2013-08-21T10:06:34Z					cellular_component											owl:Class	
GO:0071091	biolink:NamedThing	alpha1-beta1 integrin-tissue transglutaminase complex	A protein complex that consists of an alpha1-beta1 integrin complex bound to tissue transglutaminase.	tmpzr1t_l9r_go_relaxed.owl	ITGA1-ITGB1-TGM2 complex							mah	2009-11-06T04:46:44Z					cellular_component											owl:Class	
GO:0031331	biolink:NamedThing	positive regulation of cellular catabolic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of cellular catabolism|positive regulation of cellular breakdown|up-regulation of cellular catabolic process|positive regulation of cellular degradation|up regulation of cellular catabolic process|activation of cellular catabolic process|upregulation of cellular catabolic process|stimulation of cellular catabolic process													biological_process											owl:Class	
GO:0034161	biolink:NamedThing	positive regulation of toll-like receptor 8 signaling pathway	Any process that activates or increases the frequency, rate, or extent of toll-like receptor 8 signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of toll-like receptor 8 signalling pathway|positive regulation of TLR8 signaling pathway													biological_process											owl:Class	
GO:0034123	biolink:NamedThing	positive regulation of toll-like receptor signaling pathway	Any process that activates or increases the frequency, rate, or extent of toll-like receptor signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of toll-like receptor signalling pathway|positive regulation of TLR signaling pathway													biological_process											owl:Class	
GO:0038036	biolink:NamedThing	sphingosine-1-phosphate receptor activity	Combining with the sphingolipid sphingosine-1-phosphate (S1P), and transmitting the signal across the membrane by activating an associated G-protein.	tmpzr1t_l9r_go_relaxed.owl	S1P receptor activity							bf	2011-10-28T03:46:54Z					molecular_function											owl:Class	
GO:0045125	biolink:NamedThing	bioactive lipid receptor activity	Combining with a bioactive lipid and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. A bioactive lipid is a lipid for which changes in lipid levels result in functional consequences in a variety of cellular processes.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0018075	biolink:NamedThing	peptidyl-phenylalanine bromination	The bromination of phenylalanine.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0176|RESID:AA0174|RESID:AA0175									biological_process											owl:Class	
GO:0018207	biolink:NamedThing	peptidyl-phenylalanine modification	The modification of peptidyl-phenylalanine.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0031246	biolink:NamedThing	intrinsic component of periplasmic side of cell outer membrane	The component of the cell outer membrane consisting of the gene products that that penetrate the periplasmic side of the cell outer membrane only, either directly or via some covalently attached hydrophobic anchor.	tmpzr1t_l9r_go_relaxed.owl	intrinsic to internal side of cell outer membrane|intrinsic to internal side of outer membrane|intrinsic to external side of cell outer membrane|intrinsic to internal leaflet of cell outer membrane													cellular_component											owl:Class	
GO:0031224	biolink:NamedThing	intrinsic component of membrane	The component of a membrane consisting of the gene products having some covalently attached portion, for example part of a peptide sequence or some other covalently attached group such as a GPI anchor, which spans or is embedded in one or both leaflets of the membrane.	tmpzr1t_l9r_go_relaxed.owl	intrinsic to membrane					Note that proteins intrinsic to membranes cannot be removed without disrupting the membrane, e.g. by detergent.								cellular_component											owl:Class	
GO:1900006	biolink:NamedThing	positive regulation of dendrite development	Any process that activates or increases the frequency, rate or extent of dendrite development.	tmpzr1t_l9r_go_relaxed.owl	up regulation of dendrite development							hjd	2012-01-09T10:41:31Z					biological_process											owl:Class	
GO:0046519	biolink:NamedThing	sphingoid metabolic process	The chemical reactions and pathways involving sphingoids, any of a class of compounds comprising sphinganine and its homologues and stereoisomers, and derivatives of these compounds.	tmpzr1t_l9r_go_relaxed.owl	sphingoid base metabolic process|sphingoid base metabolism|sphingoid metabolism													biological_process											owl:Class	
GO:0097446	biolink:NamedThing	protein localization to eisosome filament	A process in which a protein is transported to, and/or maintained in, a specific location in a eisosome filament (also called linear eisosome), a filamentous cortical structure formed, in S. pombe, by the eisosome component Pil1.	tmpzr1t_l9r_go_relaxed.owl	protein localization to linear eisosome							pr	2012-12-17T09:37:49Z					biological_process											owl:Class	
GO:0072697	biolink:NamedThing	protein localization to cell cortex	A process in which a protein is transported to, or maintained in, the cell cortex.	tmpzr1t_l9r_go_relaxed.owl	protein localisation to cell cortex							mah	2012-04-11T01:16:33Z					biological_process											owl:Class	
GO:0052670	biolink:NamedThing	geraniol kinase activity	Catalysis of the reaction: geraniol + nucleoside triphosphate = geranyl monophosphate + nucleoside diphosphate.	tmpzr1t_l9r_go_relaxed.owl	geraniol phosphotransferase activity							ai	2011-04-11T03:14:02Z					molecular_function											owl:Class	
GO:0052673	biolink:NamedThing	prenol kinase activity	Catalysis of the reaction: prenol + nucleoside triphosphate = prenyl phosphate + nucleoside diphosphate activity.	tmpzr1t_l9r_go_relaxed.owl	prenyl alcohol kinase activity|prenol phosphotransferase activity|prenyl alcohol phosphotransferase activity							ai	2011-04-11T04:02:23Z					molecular_function											owl:Class	
GO:1990937	biolink:NamedThing	xylan acetylation	The addition of one or more acetyl groups to a xylan molecule.	tmpzr1t_l9r_go_relaxed.owl								tb	2016-03-30T22:10:22Z					biological_process											owl:Class	
GO:2001046	biolink:NamedThing	positive regulation of integrin-mediated signaling pathway	Any process that activates or increases the frequency, rate or extent of integrin-mediated signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of integrin-mediated signalling pathway							bf	2011-08-31T03:49:19Z					biological_process											owl:Class	
GO:0009701	biolink:NamedThing	isoflavonoid phytoalexin biosynthetic process	The chemical reactions and pathways resulting in the formation of isoflavonoid phytoalexins, a group of water-soluble phenolic derivatives isomeric with flavonoids that possess antibiotic activity and are produced by plant tissues in response to infection.	tmpzr1t_l9r_go_relaxed.owl	isoflavonoid phytoalexin formation|isoflavonoid phytoalexin biosynthesis|isoflavonoid phytoalexin anabolism|isoflavonoid phytoalexin synthesis													biological_process											owl:Class	
GO:0052315	biolink:NamedThing	phytoalexin biosynthetic process	The chemical reactions and pathways resulting in the formation of phytoalexins, any of a range of substances produced by plants as part of their defense response.	tmpzr1t_l9r_go_relaxed.owl	phytoalexin biosynthesis													biological_process											owl:Class	
GO:0015575	biolink:NamedThing	mannitol transmembrane transporter activity	Enables the transfer of mannitol from one side of a membrane to the other. Mannitol is the alditol derived from D-mannose by reduction of the aldehyde group.	tmpzr1t_l9r_go_relaxed.owl	mannitol permease activity											GO:0015586		molecular_function											owl:Class	
GO:0030168	biolink:NamedThing	platelet activation	A series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue. These events include shape change, adhesiveness, aggregation, and release reactions. When carried through to completion, these events lead to the formation of a stable hemostatic plug.	tmpzr1t_l9r_go_relaxed.owl	blood coagulation, platelet activation													biological_process											owl:Class	
GO:0001775	biolink:NamedThing	cell activation	A change in the morphology or behavior of a cell resulting from exposure to an activating factor such as a cellular or soluble ligand.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0010601	biolink:NamedThing	positive regulation of auxin biosynthetic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of auxins, plant hormones that regulate aspects of plant growth.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0010600	biolink:NamedThing	regulation of auxin biosynthetic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of auxins, plant hormones that regulate aspects of plant growth.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0051986	biolink:NamedThing	negative regulation of attachment of spindle microtubules to kinetochore	Any process that stops, prevents, or reduces the frequency, rate or extent of the attachment of spindle microtubules to the kinetochore.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of attachment of spindle microtubules to kinetochore|downregulation of attachment of spindle microtubules to kinetochore|inhibition of attachment of spindle microtubules to kinetochore|down regulation of attachment of spindle microtubules to kinetochore													biological_process											owl:Class	
GO:0051988	biolink:NamedThing	regulation of attachment of spindle microtubules to kinetochore	Any process that modulates the frequency, rate or extent of the attachment of spindle microtubules to the kinetochore.	tmpzr1t_l9r_go_relaxed.owl	regulation of kinetochore-microtubule attachment													biological_process											owl:Class	
GO:0042924	biolink:NamedThing	neuromedin U binding	Interacting selectively and non-covalently and stoichiometrically with neuromedin U, a hypothalamic peptide involved in energy homeostasis and stress responses.	tmpzr1t_l9r_go_relaxed.owl	NMU binding													molecular_function											owl:Class	
GO:0043713	biolink:NamedThing	(R)-2-hydroxyisocaproate dehydrogenase activity	Catalysis of the reaction: 2-oxoisocaproate + NADH + H+ = (R)-2-hydroxyisocaproate + NAD+.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0032277	biolink:NamedThing	negative regulation of gonadotropin secretion	Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a gonadotropin.	tmpzr1t_l9r_go_relaxed.owl	inhibition of gonadotropin secretion|down-regulation of gonadotropin secretion|down regulation of gonadotropin secretion|negative regulation of gonadotrophin secretion|downregulation of gonadotropin secretion													biological_process											owl:Class	
GO:1905535	biolink:NamedThing	regulation of eukaryotic translation initiation factor 4F complex assembly	Any process that modulates the frequency, rate or extent of eukaryotic translation initiation factor 4F complex assembly.	tmpzr1t_l9r_go_relaxed.owl	regulation of eIF-4F assembly|regulation of eIF4F assembly							bc	2016-10-06T14:04:58Z					biological_process											owl:Class	
GO:2000213	biolink:NamedThing	positive regulation of glutamate metabolic process	Any process that activates or increases the frequency, rate or extent of glutamate metabolic process.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of glutamic acid metabolism|positive regulation of glutamate metabolism|positive regulation of glutamic acid metabolic process							mah	2010-11-03T02:43:59Z					biological_process											owl:Class	
GO:0051731	biolink:NamedThing	polynucleotide 5'-hydroxyl-kinase activity	Catalysis of the reaction: NTP + 5'-dephosphopolynucleotide = NDP + 5'-phosphopolynucleotide. The polynucleotide may be DNA or RNA.	tmpzr1t_l9r_go_relaxed.owl	polynucleotide 5'-hydroxy-kinase activity|PNK|polynucleotide kinase activity|polynucleotide 5'-hydroxyl kinase (phosphorylating) activity|5'-hydroxyl polynucleotide kinase activity|5'-dephosphopolynucleotide kinase activity													molecular_function											owl:Class	
GO:0052910	biolink:NamedThing	23S rRNA (adenine(2085)-N(6))-dimethyltransferase activity	Catalysis of the reaction: 2 S-adenosyl-L-methionine + adenine(2085) in 23S rRNA = 2 S-adenosyl-L-homocysteine + N(6)-dimethyladenine(2085) in 23S rRNA.	tmpzr1t_l9r_go_relaxed.owl	ermC 23S rRNA methyltransferase activity|rRNA:m(6)A methyltransferase ermC' activity|rRNA methyltransferase ermC' activity				MetaCyc:RXN-11597|RHEA:42784|EC:2.1.1.184									molecular_function											owl:Class	
GO:0008988	biolink:NamedThing	rRNA (adenine-N6-)-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing N6-methyladenine.	tmpzr1t_l9r_go_relaxed.owl	ribosomal ribonucleate adenine 6-methyltransferase activity|ErmC 23S rRNA methyltransferase|ribonucleic acid-adenine (N(6)) methylase activity|ribonucleic acid-adenine (N6) methylase activity|S-adenosyl-L-methionine:rRNA (adenine-6-N-)-methyltransferase activity|gene ksgA methyltransferase|S-adenosyl-L-methionine:rRNA (adenine-N6-)-methyltransferase activity													molecular_function											owl:Class	
GO:1904507	biolink:NamedThing	positive regulation of telomere maintenance in response to DNA damage	Any process that activates or increases the frequency, rate or extent of telomere maintenance in response to DNA damage.	tmpzr1t_l9r_go_relaxed.owl	upregulation of DNA damage response, telomere maintenance|up-regulation of telomere maintenance in response to DNA damage|upregulation of telomere maintenance in response to DNA damage|activation of telomere maintenance in response to DNA damage|positive regulation of DNA damage response, telomere maintenance|activation of DNA damage response, telomere maintenance|up-regulation of DNA damage response, telomere maintenance|up regulation of DNA damage response, telomere maintenance|up regulation of telomere maintenance in response to DNA damage							nc	2015-07-24T16:06:09Z					biological_process											owl:Class	
GO:1904505	biolink:NamedThing	regulation of telomere maintenance in response to DNA damage	Any process that modulates the frequency, rate or extent of telomere maintenance in response to DNA damage.	tmpzr1t_l9r_go_relaxed.owl	regulation of DNA damage response, telomere maintenance							nc	2015-07-24T16:05:55Z					biological_process											owl:Class	
GO:0007027	biolink:NamedThing	negative regulation of axonemal microtubule depolymerization	Any process that stops, prevents, or reduces the frequency, rate or extent of the depolymerization of the specialized microtubules of the axoneme.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of microtubule depolymerization in axoneme|axonemal microtubule stabilization													biological_process											owl:Class	
GO:0031345	biolink:NamedThing	negative regulation of cell projection organization	Any process that stops, prevents, or reduces the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell projections.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of cell projection organization|inhibition of cell projection organization|negative regulation of cell projection organization and biogenesis|downregulation of cell projection organization|down regulation of cell projection organization|negative regulation of cell projection organisation													biological_process											owl:Class	
GO:0090076	biolink:NamedThing	relaxation of skeletal muscle	A process in which the extent of skeletal muscle tissue contraction is reduced. Muscle relaxation involves the removal of calcium from the cytoplasm to the sarcoplasmic reticulum lumen through the action of Ca2+ ATPases.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-09-11T11:44:32Z					biological_process											owl:Class	
GO:0090075	biolink:NamedThing	relaxation of muscle	A process in which the extent of muscle contraction is reduced. Muscle relaxation can involve a number of processes including the removal of calcium from the cytoplasm to the sarcoplasmic reticulum lumen through the action of Ca2+ ATPases. In some muscles, calcium-independent pathways also play a role in muscle relaxation by decreasing the phosphorylation state of myosin light chain.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-09-11T11:43:38Z					biological_process											owl:Class	
GO:0000147	biolink:NamedThing	actin cortical patch assembly	Assembly of an actin cortical patch, a discrete actin-containing structure found at the plasma membrane of fungal cells.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0030866	biolink:NamedThing	cortical actin cytoskeleton organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of actin-based cytoskeletal structures in the cell cortex, i.e. just beneath the plasma membrane.	tmpzr1t_l9r_go_relaxed.owl	actin cortex stabilization|cortical resistance|cortical actin cytoskeleton organisation|cortical actin cytoskeleton stabilization|cortical actin cytoskeleton organization and biogenesis											GO:0033109		biological_process											owl:Class	
GO:1900967	biolink:NamedThing	positive regulation of methanophenazine metabolic process	Any process that activates or increases the frequency, rate or extent of methanophenazine metabolic process.	tmpzr1t_l9r_go_relaxed.owl	up regulation of methanophenazine metabolic process|up-regulation of methanophenazine metabolism|activation of methanophenazine metabolic process|up-regulation of methanophenazine metabolic process|activation of methanophenazine metabolism|upregulation of methanophenazine metabolism|upregulation of methanophenazine metabolic process|up regulation of methanophenazine metabolism|positive regulation of methanophenazine metabolism							tt	2012-06-14T03:55:56Z					biological_process											owl:Class	
GO:0010049	biolink:NamedThing	acquisition of plant reproductive competence	The process in which a plant acquires the ability to respond to a floral inductive signal.	tmpzr1t_l9r_go_relaxed.owl	acquisition of reproductive competence													biological_process											owl:Class	
GO:0086004	biolink:NamedThing	regulation of cardiac muscle cell contraction	Any process that modulates the frequency, rate or extent of cardiac muscle cell contraction.	tmpzr1t_l9r_go_relaxed.owl								tb	2011-11-10T07:49:10Z					biological_process											owl:Class	
GO:0047343	biolink:NamedThing	glucose-1-phosphate cytidylyltransferase activity	Catalysis of the reaction: alpha-D-glucose 1-phosphate + CTP = CDP-D-glucose + diphosphate.	tmpzr1t_l9r_go_relaxed.owl	cytidine diphosphate glucose pyrophosphorylase activity|cytidine diphosphate-D-glucose pyrophosphorylase activity|CTP:glucose-1-phosphate cytidylyltransferase activity|cytidine diphosphoglucose pyrophosphorylase activity|CTP:alpha-D-glucose-1-phosphate cytidylyltransferase activity|CDP glucose pyrophosphorylase activity|CTP:D-glucose-1-phosphate cytidylyltransferase activity|CDP-glucose diphosphorylase activity|CDP-glucose pyrophosphorylase activity				RHEA:18213|EC:2.7.7.33|MetaCyc:2.7.7.33-RXN|KEGG_REACTION:R00956									molecular_function											owl:Class	
GO:0070567	biolink:NamedThing	cytidylyltransferase activity	Catalysis of the transfer of a cytidylyl group to an acceptor.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-04-15T11:05:22Z					molecular_function											owl:Class	
GO:0035836	biolink:NamedThing	ergot alkaloid metabolic process	The chemical reactions and pathways involving an ergot alkaloid, an indole alkaloid.	tmpzr1t_l9r_go_relaxed.owl	ergot alkaloid metabolism							bf	2011-05-04T03:23:13Z					biological_process											owl:Class	
GO:0046855	biolink:NamedThing	inositol phosphate dephosphorylation	The process of removing a phosphate group from any mono- or polyphosphorylated inositol.	tmpzr1t_l9r_go_relaxed.owl	myo-inositol phosphate dephosphorylation													biological_process											owl:Class	
GO:0071545	biolink:NamedThing	inositol phosphate catabolic process	The chemical reactions and pathways resulting in the breakdown of an inositol phosphate, 1,2,3,4,5,6-cyclohexanehexol, with one or more phosphate groups attached.	tmpzr1t_l9r_go_relaxed.owl	myo-inositol phosphate catabolic process|inositol phosphate breakdown|inositol phosphate catabolism|inositol phosphate degradation					See also the biological process term 'inositol phosphate dephosphorylation ; GO:0046855'.		mah	2010-01-12T05:07:45Z					biological_process											owl:Class	
GO:0061961	biolink:NamedThing	positive regulation of heme oxygenase activity	Any process that activates or increases the frequency or rate of heme oxygenase activity.	tmpzr1t_l9r_go_relaxed.owl								dph	2018-01-22T20:32:05Z					biological_process											owl:Class	
GO:0046902	biolink:NamedThing	regulation of mitochondrial membrane permeability	Any process that modulates the frequency, rate or extent of the passage or uptake of molecules by the mitochondrial membrane.	tmpzr1t_l9r_go_relaxed.owl	regulation of mitochondrial envelope permeability|regulation of transport across mitochondrial membrane													biological_process											owl:Class	
GO:1900789	biolink:NamedThing	pseurotin A catabolic process	The chemical reactions and pathways resulting in the breakdown of pseurotin A.	tmpzr1t_l9r_go_relaxed.owl	pseurotin A breakdown|Pseurotin catabolic process|Pseurotin catabolism|Pseurotin breakdown|Pseurotin degradation|pseurotin A catabolism|pseurotin A degradation							di	2012-06-04T09:37:41Z					biological_process											owl:Class	
GO:0006749	biolink:NamedThing	glutathione metabolic process	The chemical reactions and pathways involving glutathione, the tripeptide glutamylcysteinylglycine, which acts as a coenzyme for some enzymes and as an antioxidant in the protection of sulfhydryl groups in enzymes and other proteins; it has a specific role in the reduction of hydrogen peroxide (H2O2) and oxidized ascorbate, and it participates in the gamma-glutamyl cycle.	tmpzr1t_l9r_go_relaxed.owl	oxidized glutathione reduction|glutathione metabolism													biological_process											owl:Class	
GO:0046602	biolink:NamedThing	regulation of mitotic centrosome separation	Any process that modulates the frequency, rate or extent of the separation of duplicated centrosome components at the beginning of mitosis.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0061789	biolink:NamedThing	dense core granule priming	A process that converts unprimed dense core granules (DCVs) to a pool of primed vesicles that are capable of fusing with the plasma membrane (fusion-competent) and thereby releasing their contents. Priming typically occurs after docking.	tmpzr1t_l9r_go_relaxed.owl	large dense-core vesicle priming|dense core vesicle priming|LDCV priming							dph	2016-09-08T15:41:30Z					biological_process											owl:Class	
GO:0045924	biolink:NamedThing	regulation of female receptivity	Any process that modulates the frequency, rate or extent of the willingness or readiness of a female to receive male advances.	tmpzr1t_l9r_go_relaxed.owl	female receptivity											GO:0060181		biological_process											owl:Class	
GO:0015606	biolink:NamedThing	spermidine transmembrane transporter activity	Enables the transfer of spermidine, N-(3-aminopropyl)-1,4-diaminobutane, from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0008470	biolink:NamedThing	isovaleryl-CoA dehydrogenase activity	Catalysis of the reaction: 3-methylbutanoyl-CoA + ETF = 3-methylbut-2-enoyl-CoA + reduced ETF.	tmpzr1t_l9r_go_relaxed.owl	isovaleryl-coenzyme A dehydrogenase activity|3-methylbutanoyl-CoA:acceptor oxidoreductase activity|3-methylbutanoyl-CoA:(acceptor) oxidoreductase activity|isovaleroyl-coenzyme A dehydrogenase activity				Reactome:R-HSA-70745|EC:1.3.8.4|MetaCyc:ISOVALERYL-COA-FAD-RXN|RHEA:12276									molecular_function											owl:Class	
GO:0003995	biolink:NamedThing	acyl-CoA dehydrogenase activity	Catalysis of the reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor.	tmpzr1t_l9r_go_relaxed.owl	acyl-CoA reductase activity|acyl-CoA:acceptor 2,3-oxidoreductase activity|long-chain acyl coenzyme A dehydrogenase activity|medium-chain acyl-CoA dehydrogenase activity|long-chain acyl-CoA dehydrogenase activity|acyl CoA dehydrogenase activity|medium-chain acyl-coenzyme A dehydrogenase activity|acyl dehydrogenase activity|acyl coenzyme A dehydrogenase activity|general acyl CoA dehydrogenase activity|fatty acyl coenzyme A dehydrogenase activity|fatty-acyl-CoA dehydrogenase activity|acyl-CoA:(acceptor) 2,3-oxidoreductase activity				Reactome:R-HSA-70859|Reactome:R-HSA-77327|Reactome:R-HSA-109341|Reactome:R-HSA-77345|MetaCyc:LONG-CHAIN-FATTY-ACYL-COA-REDUCTASE-RXN|MetaCyc:ACYLCOADEHYDROG-RXN|Reactome:R-HSA-77338|Reactome:R-HSA-77319|Reactome:R-HSA-77274|Reactome:R-HSA-77299|Reactome:R-HSA-77263|Reactome:R-HSA-5695989|Reactome:R-HSA-5695980|EC:1.3.99.3|Reactome:R-HSA-70800							GO:0019109		molecular_function											owl:Class	
GO:0046956	biolink:NamedThing	positive phototaxis	The directed movement of a cell or organism towards a source of light.	tmpzr1t_l9r_go_relaxed.owl	positive taxis in response to light|positive phototactic behaviour|positive phototactic behavior											GO:0046954		biological_process											owl:Class	
GO:0030842	biolink:NamedThing	regulation of intermediate filament depolymerization	Any process that modulates the frequency, rate or extent of the disassembly of intermediate filaments by the removal of monomers from a filament.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0045108	biolink:NamedThing	regulation of intermediate filament polymerization or depolymerization	Any process that modulates the frequency, rate or extent of the assembly or disassembly of intermediate filaments by the addition or removal of monomers from a filament; this usually occurs through the opposing action of kinases and phosphatases.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0033043	biolink:NamedThing	regulation of organelle organization	Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle.	tmpzr1t_l9r_go_relaxed.owl	regulation of organelle organization and biogenesis|regulation of organelle organisation													biological_process											owl:Class	
GO:0033727	biolink:NamedThing	aldehyde dehydrogenase (FAD-independent) activity	Catalysis of the reaction: an aldehyde + H2O + acceptor = a carboxylate + reduced acceptor.	tmpzr1t_l9r_go_relaxed.owl	Mop|AORDd|aldehyde:acceptor oxidoreductase (FAD-independent) activity|aldehyde oxidoreductase activity				EC:1.2.99.7|MetaCyc:1.2.99.3-RXN|MetaCyc:CARBOXYLATE-REDUCTASE-RXN|MetaCyc:1.2.99.7-RXN									molecular_function											owl:Class	
GO:1905951	biolink:NamedThing	mitochondrion DNA recombination	Any DNA recombination that takes place in mitochondrion.	tmpzr1t_l9r_go_relaxed.owl	DNA recombination in mitochondria							vw	2017-02-19T10:48:17Z					biological_process											owl:Class	
GO:0032042	biolink:NamedThing	mitochondrial DNA metabolic process	The chemical reactions and pathways involving mitochondrial DNA.	tmpzr1t_l9r_go_relaxed.owl	mitochondrial DNA metabolism|mtDNA metabolic process|mtDNA metabolism													biological_process											owl:Class	
GO:0061921	biolink:NamedThing	peptidyl-lysine propionylation	The propionylation of peptidyl-lysine.	tmpzr1t_l9r_go_relaxed.owl								dph	2017-08-02T13:37:14Z					biological_process											owl:Class	
GO:0043543	biolink:NamedThing	protein acylation	The addition of an acyl group, any group or radical of the form RCO- where R is an organic group, to a protein amino acid.	tmpzr1t_l9r_go_relaxed.owl	protein amino acid acylation													biological_process											owl:Class	
GO:0072281	biolink:NamedThing	mesenchymal stem cell differentiation involved in metanephric nephron morphogenesis	The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal stem cell that contributes to the shaping of a nephronin the metanephros. A mesenchymal stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-04-01T03:22:06Z					biological_process											owl:Class	
GO:0072497	biolink:NamedThing	mesenchymal stem cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal stem cell. A mesenchymal stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-12-15T12:59:30Z					biological_process											owl:Class	
GO:0046055	biolink:NamedThing	dGMP catabolic process	The chemical reactions and pathways resulting in the breakdown of dGMP, deoxyguanosine monophosphate (2'-deoxyguanosine 5'-phosphate).	tmpzr1t_l9r_go_relaxed.owl	dGMP breakdown|dGMP catabolism|dGMP degradation													biological_process											owl:Class	
GO:0009172	biolink:NamedThing	purine deoxyribonucleoside monophosphate catabolic process	The chemical reactions and pathways resulting in the breakdown of purine deoxyribonucleoside monophosphate, a compound consisting of a purine base linked to a deoxyribose sugar esterified with phosphate on the sugar.	tmpzr1t_l9r_go_relaxed.owl	purine deoxyribonucleoside monophosphate catabolism|purine deoxyribonucleoside monophosphate breakdown|purine deoxyribonucleoside monophosphate degradation													biological_process											owl:Class	
GO:0072356	biolink:NamedThing	chromosome passenger complex localization to kinetochore	A cellular protein complex localization that acts on a chromosome passenger complex; as a result, the complex is transported to, or maintained in, a specific location at the kinetochore. A chromosome passenger complex is a protein complex that contains the BIR-domain-containing protein Survivin, Aurora B kinase, INCENP and Borealin, and coordinates various events based on its location to different structures during the course of mitosis.	tmpzr1t_l9r_go_relaxed.owl	chromosomal passenger complex localization to kinetochore|CPC localization to kinetochore|CPC complex localization to kinetochore|chromosome passenger complex localisation to kinetochore							mah	2010-11-15T11:30:38Z					biological_process											owl:Class	
GO:0075307	biolink:NamedThing	positive regulation of conidium formation	Any process that activates, maintains or increases the frequency, rate or extent of conidium formation, a process of producing non-motile spores, called conidia, via mitotic asexual reproduction in higher fungi. Conidia are haploid cells genetically identical to their haploid parent. They are produced by conversion of hyphal elements, or are borne on sporogenous cells on or within specialized structures termed conidiophores, and participate in dispersal of the fungus.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1901932	biolink:NamedThing	bicyclogermacrene metabolic process	The chemical reactions and pathways involving bicyclogermacrene.	tmpzr1t_l9r_go_relaxed.owl	bicyclogermacrene metabolism							ms	2013-02-18T14:54:52Z					biological_process											owl:Class	
GO:1902079	biolink:NamedThing	D-valine catabolic process	The chemical reactions and pathways resulting in the breakdown of D-valine.	tmpzr1t_l9r_go_relaxed.owl	D-valine degradation|D-valine catabolism|D-valine breakdown							al	2013-04-23T21:34:29Z					biological_process											owl:Class	
GO:0019478	biolink:NamedThing	D-amino acid catabolic process	The chemical reactions and pathways resulting in the breakdown of D-amino acids, the D-enantiomers of amino acids.	tmpzr1t_l9r_go_relaxed.owl	D-amino acid degradation|D-amino acid catabolism|D-amino acid breakdown													biological_process											owl:Class	
GO:0046623	biolink:NamedThing	sphingolipid floppase activity	Catalysis of the movement of a sphingolipid from the cytosolic to the exoplasmic leaftlet of a membrane, using energy from the hydrolysis of ATP.	tmpzr1t_l9r_go_relaxed.owl	sphingolipid-translocating ATPase activity|sphingolipid flippase activity|sphingolipid floppase activity (cytosolic to exoplasmic leaftlet)													molecular_function											owl:Class	
GO:0140328	biolink:NamedThing	floppase activity	Catalysis of the movement of a lipid from the cytosolic to the exoplasmic leaftlet of a membrane, using energy from the hydrolysis of ATP.	tmpzr1t_l9r_go_relaxed.owl	floppase activity (cytosolic to exoplasmic leaftlet)					Nomenclature note. Flippases and floppases are ATP-dependent transbilayer lipid translocators. According to an extensively used, though not universal, nomenclature, they catalyze lipid transfer towards the inward monolayer (flippases) or towards the outward monolayer (floppases). Scramblases are ATP-independent, non-selective, inducing non-specific transbilayer movements across the membrane. The direction of the translocation should be taken into account for annotation (from the cytosolic to the exoplasmic leaftlet of a membrane).		pg	2019-04-29T12:58:53Z					molecular_function											owl:Class	
GO:0150129	biolink:NamedThing	positive regulation of interleukin-33 production	Any process that activates or increases the frequency, rate or extent of interleukin-33 production.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of interleukin-33 secretion|positive regulation of interleukin-33 biosynthetic process							bc	2019-12-03T05:54:37Z			GO:0150125|GO:0150132		biological_process											owl:Class	
GO:0097703	biolink:NamedThing	cellular response to pulsatile fluid shear stress	Any response to pulsatile fluid shear stress that occurs at the level of a cell.	tmpzr1t_l9r_go_relaxed.owl								pr	2016-01-27T14:18:23Z					biological_process											owl:Class	
GO:0097701	biolink:NamedThing	response to pulsatile fluid shear stress	Any response to fluid shear stress where the fluid is flowing across a solid surface with periodic variations. For example, the endothelium in straight parts of the artery tree is subjected to pulsatile shear stress with a significant forward direction, which is believed to be an important physiological stimulus enhancing vessel compliance and conferring anti-thrombotic, anti-adhesive, and anti-inflammatory effects.	tmpzr1t_l9r_go_relaxed.owl								pr	2016-01-27T14:13:31Z					biological_process											owl:Class	
GO:0002812	biolink:NamedThing	biosynthetic process of antibacterial peptides active against Gram-negative bacteria	The chemical reactions and pathways resulting in the formation of an antibacterial peptide with activity against Gram-negative bacteria.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0002780	biolink:NamedThing	antibacterial peptide biosynthetic process	The chemical reactions and pathways resulting in the formation of an antibacterial peptide.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0035681	biolink:NamedThing	toll-like receptor 15 signaling pathway	Any series of molecular signals generated as a consequence of binding to toll-like receptor 15.	tmpzr1t_l9r_go_relaxed.owl	toll-like receptor 15 signalling pathway|TLR15 signaling pathway							bf	2011-02-21T02:38:47Z					biological_process											owl:Class	
GO:0019241	biolink:NamedThing	citrulline catabolic process	The chemical reactions and pathways resulting in the breakdown of citrulline, N5-carbamoyl-L-ornithine, an alpha amino acid not found in proteins.	tmpzr1t_l9r_go_relaxed.owl	citrulline catabolism|citrulline degradation|citrulline breakdown				MetaCyc:CITRULLINE-DEG-PWY									biological_process											owl:Class	
GO:0097753	biolink:NamedThing	membrane bending	A membrane organization process resulting in the bending of a membrane.	tmpzr1t_l9r_go_relaxed.owl	membrane curvature							pr	2017-01-25T16:37:06Z					biological_process											owl:Class	
GO:0090033	biolink:NamedThing	positive regulation of filamentous growth	Any process that increases the frequency, rate or extent of the process in which a multicellular organism or a group of unicellular organisms grow in a threadlike, filamentous shape.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-08-03T11:04:21Z					biological_process											owl:Class	
GO:0010570	biolink:NamedThing	regulation of filamentous growth	Any process that modulates the frequency, rate or extent of the process in which a multicellular organism or a group of unicellular organisms grow in a threadlike, filamentous shape.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0016272	biolink:NamedThing	prefoldin complex	A multisubunit chaperone that is capable of delivering unfolded proteins to cytosolic chaperonin, which it acts as a cofactor for. In humans, the complex is a heterohexamer of two PFD-alpha and four PFD-beta type subunits. In Saccharomyces cerevisiae, it also acts in the nucleus to regulate the rate of elongation by RNA polymerase II via a direct effect on histone dynamics.	tmpzr1t_l9r_go_relaxed.owl	GIM complex				Wikipedia:Prefoldin									cellular_component											owl:Class	
GO:0043149	biolink:NamedThing	stress fiber assembly	The aggregation, arrangement and bonding together of a set of components to form a stress fiber. A stress fiber is a contractile actin filament bundle that consists of short actin filaments with alternating polarity.	tmpzr1t_l9r_go_relaxed.owl	actin cable formation|actin cable assembly|stress fibre biosynthesis|stress fibre formation													biological_process											owl:Class	
GO:0030038	biolink:NamedThing	contractile actin filament bundle assembly	Assembly of actin filament bundles in which the filaments are loosely packed (approximately 30-60 nm apart) and arranged with opposing polarities; the loose packing allows myosin (usually myosin-II) to enter the bundle.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0050732	biolink:NamedThing	negative regulation of peptidyl-tyrosine phosphorylation	Any process that stops, prevents, or reduces the frequency, rate or extent of the phosphorylation of peptidyl-tyrosine.	tmpzr1t_l9r_go_relaxed.owl	inhibition of peptidyl-tyrosine phosphorylation|down-regulation of peptidyl-tyrosine phosphorylation|downregulation of peptidyl-tyrosine phosphorylation|down regulation of peptidyl-tyrosine phosphorylation													biological_process											owl:Class	
GO:0050730	biolink:NamedThing	regulation of peptidyl-tyrosine phosphorylation	Any process that modulates the frequency, rate or extent of the phosphorylation of peptidyl-tyrosine.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1901293	biolink:NamedThing	nucleoside phosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of a nucleoside phosphate.	tmpzr1t_l9r_go_relaxed.owl	nucleoside phosphate biosynthesis|nucleoside phosphate synthesis|nucleoside phosphate anabolism|nucleoside phosphate formation							bf	2012-08-20T12:33:45Z					biological_process											owl:Class	
GO:0034654	biolink:NamedThing	nucleobase-containing compound biosynthetic process	The chemical reactions and pathways resulting in the formation of nucleobases, nucleosides, nucleotides and nucleic acids.	tmpzr1t_l9r_go_relaxed.owl	nucleobase, nucleoside, nucleotide and nucleic acid formation|nucleobase, nucleoside, nucleotide and nucleic acid anabolism|nucleobase, nucleoside, nucleotide and nucleic acid biosynthesis|nucleobase, nucleoside, nucleotide and nucleic acid synthesis													biological_process											owl:Class	
GO:1900992	biolink:NamedThing	(-)-secologanin metabolic process	The chemical reactions and pathways involving (-)-secologanin.	tmpzr1t_l9r_go_relaxed.owl	(-)-secologanin metabolism							yaf	2012-06-14T09:51:17Z					biological_process											owl:Class	
GO:0001100	biolink:NamedThing	negative regulation of exit from mitosis	Any process involved in the inhibition of progression from anaphase/telophase (high mitotic CDK activity) to G1 (low mitotic CDK activity).	tmpzr1t_l9r_go_relaxed.owl	inhibition of exit from mitosis|downregulation of exit from mitosis|down-regulation of exit from mitosis|down regulation of exit from mitosis													biological_process											owl:Class	
GO:0034597	biolink:NamedThing	phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity	Catalysis of the reaction: 1-phosphatidyl-myo-inositol 4,5-bisphosphate + H2O = 1-phosphatidyl-1D-myo-inositol 3-phosphate + phosphate.	tmpzr1t_l9r_go_relaxed.owl	1-phosphatidyl-1D-myo-inositol-4,5-bisphosphate 4-phosphohydrolase activity|inositol polyphosphate 4-phosphatase type II activity|phosphatidyl-myo-inositol-4,5-bisphosphate 4-phosphohydrolase activity				Reactome:R-HSA-6810410|EC:3.1.3.66|MetaCyc:3.1.3.66-RXN									molecular_function											owl:Class	
GO:0034596	biolink:NamedThing	phosphatidylinositol phosphate 4-phosphatase activity	Catalysis of the removal of the 4-phosphate group of a phosphatidylinositol phosphate.	tmpzr1t_l9r_go_relaxed.owl	PI(4)P-phosphatase activity|inositol 4-phosphatase|PtdIns4P-phosphatase activity|phosphoinositide 4-phosphatase activity|PI4P-phosphatase activity				Reactome:R-HSA-8849969|Reactome:R-HSA-1676133|Reactome:R-HSA-1675988|Reactome:R-HSA-1676124									molecular_function											owl:Class	
GO:1900689	biolink:NamedThing	regulation of gliotoxin biosynthetic process	Any process that modulates the frequency, rate or extent of gliotoxin biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of gliotoxin formation|regulation of gliotoxin anabolism|regulation of gliotoxin synthesis|regulation of gliotoxin biosynthesis							di	2012-05-22T04:51:38Z					biological_process											owl:Class	
GO:0042762	biolink:NamedThing	regulation of sulfur metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving sulfur, the nonmetallic element sulfur or compounds that contain sulfur.	tmpzr1t_l9r_go_relaxed.owl	regulation of sulphur metabolic process|regulation of sulfur metabolism|regulation of sulphur metabolism													biological_process											owl:Class	
GO:0006282	biolink:NamedThing	regulation of DNA repair	Any process that modulates the frequency, rate or extent of DNA repair.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0044840	biolink:NamedThing	gut granule	A lysosome-related organelle contained within the intestinal cells of the nematode C. elegans. Gut granules are acidified, birefringent, autofluorescent, and contain the vacuolar H+-ATPase. They also serve as sites of cellular zinc storage.	tmpzr1t_l9r_go_relaxed.owl								jl	2014-03-25T11:56:41Z					cellular_component											owl:Class	
GO:0031410	biolink:NamedThing	cytoplasmic vesicle	A vesicle found in the cytoplasm of a cell.	tmpzr1t_l9r_go_relaxed.owl	cytoplasmic membrane-enclosed vesicle|cytoplasmic, membrane-bounded vesicle|cytoplasmic membrane bounded vesicle				NIF_Subcellular:sao180601769							GO:0016023		cellular_component											owl:Class	
GO:0032508	biolink:NamedThing	DNA duplex unwinding	The process in which interchain hydrogen bonds between two strands of DNA are broken or 'melted', generating a region of unpaired single strands.	tmpzr1t_l9r_go_relaxed.owl	DNA unwinding|duplex DNA melting					Note that this term refers to a geometric change in DNA conformation, and should not be confused with 'DNA topological change ; GO:0006265'.								biological_process											owl:Class	
GO:0032392	biolink:NamedThing	DNA geometric change	The process in which a transformation is induced in the geometry of a DNA double helix, resulting in a change in twist, writhe, or both, but with no change in linking number. Includes the unwinding of double-stranded DNA by helicases.	tmpzr1t_l9r_go_relaxed.owl						Note that DNA geometric change and DNA topological change (GO:0006265) are distinct, but are usually coupled in vivo.								biological_process											owl:Class	
GO:0046057	biolink:NamedThing	dADP catabolic process	The chemical reactions and pathways resulting in the breakdown of dADP, deoxyadenosine diphosphate (2'-deoxyadenosine 5'-diphosphate).	tmpzr1t_l9r_go_relaxed.owl	dADP catabolism|dADP degradation|dADP breakdown													biological_process											owl:Class	
GO:0009184	biolink:NamedThing	purine deoxyribonucleoside diphosphate catabolic process	The chemical reactions and pathways resulting in the breakdown of purine deoxyribonucleoside diphosphate, a compound consisting of a purine base linked to a deoxyribose sugar esterified with diphosphate on the sugar.	tmpzr1t_l9r_go_relaxed.owl	purine deoxyribonucleoside diphosphate catabolism|purine deoxyribonucleoside diphosphate breakdown|purine deoxyribonucleoside diphosphate degradation													biological_process											owl:Class	
GO:0002915	biolink:NamedThing	negative regulation of central B cell anergy	Any process that stops, prevents, or reduces the frequency, rate, or extent of central B cell anergy.	tmpzr1t_l9r_go_relaxed.owl	down regulation of central B cell anergy|downregulation of central B cell anergy|inhibition of central B cell anergy|down-regulation of central B cell anergy													biological_process											owl:Class	
GO:0002896	biolink:NamedThing	negative regulation of central B cell tolerance induction	Any process that stops, prevents, or reduces the frequency, rate, or extent of central B cell tolerance induction.	tmpzr1t_l9r_go_relaxed.owl	downregulation of central B cell tolerance induction|down regulation of central B cell tolerance induction|down-regulation of central B cell tolerance induction|inhibition of central B cell tolerance induction													biological_process											owl:Class	
GO:0060224	biolink:NamedThing	regulation of retinal rod cell fate commitment	Any process that modulates the process in which the developmental fate of a cell becomes restricted such that it will develop into a retinal rod cell. A retinal rod cell is one of the two photoreceptor subtypes in a camera-type eye.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:2000671	biolink:NamedThing	regulation of motor neuron apoptotic process	Any process that modulates the frequency, rate or extent of motor neuron apoptotic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of motoneuron apoptosis|regulation of motor neuron apoptosis							pr	2011-05-09T10:56:17Z					biological_process											owl:Class	
GO:0043523	biolink:NamedThing	regulation of neuron apoptotic process	Any process that modulates the occurrence or rate of cell death by apoptotic process in neurons.	tmpzr1t_l9r_go_relaxed.owl	regulation of neuron programmed cell death|regulation of programmed cell death, neurons|regulation of neuron apoptosis|regulation of programmed cell death of neuronal cells|regulation of neuronal cell programmed cell death|regulation of apoptosis of neurons|regulation of apoptosis of neuronal cells													biological_process											owl:Class	
GO:0043211	biolink:NamedThing	ABC-type carbohydrate transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O = ADP + phosphate, to directly drive the transport of carbohydrates across a membrane.	tmpzr1t_l9r_go_relaxed.owl	carbohydrate ABC transporter|ATPase-coupled carbohydrate transmembrane transporter activity|carbohydrate-transporting ATPase activity|ATP-dependent carbohydrate transmembrane transporter activity	https://github.com/geneontology/go-ontology/issues/17289												molecular_function											owl:Class	
GO:0030026	biolink:NamedThing	cellular manganese ion homeostasis	Any process involved in the maintenance of an internal steady state of manganese ions at the level of a cell.	tmpzr1t_l9r_go_relaxed.owl	manganese homeostasis													biological_process											owl:Class	
GO:0032820	biolink:NamedThing	regulation of natural killer cell proliferation involved in immune response	Any process that modulates the frequency, rate or extent of natural killer cell proliferation as part of an immune response.	tmpzr1t_l9r_go_relaxed.owl	regulation of natural killer cell proliferation during immune response|regulation of NK cell proliferation during immune response													biological_process											owl:Class	
GO:0046342	biolink:NamedThing	CDP-diacylglycerol catabolic process	The chemical reactions and pathways resulting in the breakdown of CDP-diacylglycerol, CDP-1,2-diacylglycerol, a substance composed of diacylglycerol in glycosidic linkage with cytidine diphosphate.	tmpzr1t_l9r_go_relaxed.owl	CDP-diacylglycerol breakdown|CDP-diacylglycerol degradation|CDP-diacylglycerol catabolism													biological_process											owl:Class	
GO:0046341	biolink:NamedThing	CDP-diacylglycerol metabolic process	The chemical reactions and pathways involving CDP-diacylglycerol, CDP-1,2-diacylglycerol, a substance composed of diacylglycerol in glycosidic linkage with cytidine diphosphate. It is a common intermediate in phospholipid biosynthesis.	tmpzr1t_l9r_go_relaxed.owl	CDP-diacylglycerol metabolism													biological_process											owl:Class	
GO:1901567	biolink:NamedThing	fatty acid derivative binding	Binding to fatty acid derivative.	tmpzr1t_l9r_go_relaxed.owl								pr	2012-11-04T17:13:28Z					molecular_function											owl:Class	
GO:2000724	biolink:NamedThing	positive regulation of cardiac vascular smooth muscle cell differentiation	Any process that activates or increases the frequency, rate or extent of cardiac vascular smooth muscle cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of heart vascular smooth muscle cell differentiation							vk	2011-06-08T08:48:04Z					biological_process											owl:Class	
GO:0042481	biolink:NamedThing	regulation of odontogenesis	Any process that modulates the frequency, rate or extent of the formation and development of a tooth or teeth.	tmpzr1t_l9r_go_relaxed.owl	regulation of odontogenesis of calcareous or chitinous tooth|regulation of tooth development											GO:0042484		biological_process											owl:Class	
GO:2000466	biolink:NamedThing	negative regulation of glycogen (starch) synthase activity	Any process that stops, prevents or reduces the frequency, rate or extent of glycogen (starch) synthase activity.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of uridine diphosphoglucose-glycogen glucosyltransferase activity|negative regulation of UDPG-glycogen transglucosylase activity|negative regulation of UDPG-glycogen synthetase activity|negative regulation of UDPglucose:glycogen 4-alpha-D-glucosyltransferase activity|negative regulation of glycogen (starch) synthetase activity|negative regulation of UDP-glycogen synthase activity|negative regulation of UDP-glucose:glycogen 4-alpha-D-glucosyltransferase activity|negative regulation of UDP-glucose-glycogen glucosyltransferase activity							yaf	2011-03-07T04:13:14Z					biological_process											owl:Class	
GO:2000465	biolink:NamedThing	regulation of glycogen (starch) synthase activity	Any process that modulates the frequency, rate or extent of glycogen (starch) synthase activity.	tmpzr1t_l9r_go_relaxed.owl	regulation of UDPglucose:glycogen 4-alpha-D-glucosyltransferase activity|regulation of UDP-glucose-glycogen glucosyltransferase activity|regulation of UDPG-glycogen transglucosylase activity|regulation of UDPG-glycogen synthetase activity|regulation of glycogen (starch) synthetase activity|regulation of UDP-glucose:glycogen 4-alpha-D-glucosyltransferase activity|regulation of UDP-glycogen synthase activity|regulation of uridine diphosphoglucose-glycogen glucosyltransferase activity							yaf	2011-03-07T04:12:35Z					biological_process											owl:Class	
GO:0071292	biolink:NamedThing	cellular response to silver ion	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a silver ion stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-12-10T04:16:30Z					biological_process											owl:Class	
GO:0010272	biolink:NamedThing	response to silver ion	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a silver ion stimulus.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0035386	biolink:NamedThing	regulation of Roundabout signaling pathway	Any process that modulates the frequency, rate or extent of the Roundabout signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	regulation of Roundabout signalling pathway							bf	2010-03-18T02:39:24Z					biological_process											owl:Class	
GO:0009966	biolink:NamedThing	regulation of signal transduction	Any process that modulates the frequency, rate or extent of signal transduction.	tmpzr1t_l9r_go_relaxed.owl	regulation of signaling pathway|regulation of signalling pathway											GO:0035466		biological_process											owl:Class	
GO:0043153	biolink:NamedThing	entrainment of circadian clock by photoperiod	The synchronization of a circadian rhythm to photoperiod, the intermittent cycle of light (day) and dark (night).	tmpzr1t_l9r_go_relaxed.owl	photoentrainment of circadian clock													biological_process											owl:Class	
GO:0009649	biolink:NamedThing	entrainment of circadian clock	The synchronization of a circadian rhythm to environmental time cues such as light.	tmpzr1t_l9r_go_relaxed.owl	regulation of circadian rhythm phase													biological_process											owl:Class	
GO:0072355	biolink:NamedThing	histone H3-T3 phosphorylation	The modification of histone H3 by the addition of an phosphate group to a threonine residue at position 3 of the histone.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-11-12T04:28:56Z					biological_process											owl:Class	
GO:0035405	biolink:NamedThing	histone-threonine phosphorylation	The modification of histones by addition of a phosphate group to a threonine residue.	tmpzr1t_l9r_go_relaxed.owl	histone threonine phosphorylation							bf	2010-03-24T10:09:21Z					biological_process											owl:Class	
GO:1900574	biolink:NamedThing	emodin catabolic process	The chemical reactions and pathways resulting in the breakdown of emodin.	tmpzr1t_l9r_go_relaxed.owl	emodin catabolism|emodin degradation|emodin breakdown							di	2012-05-15T06:42:06Z					biological_process											owl:Class	
GO:0046710	biolink:NamedThing	GDP metabolic process	The chemical reactions and pathways involving GDP, guanosine 5'-diphosphate.	tmpzr1t_l9r_go_relaxed.owl	GDP metabolism													biological_process											owl:Class	
GO:0110143	biolink:NamedThing	magnetosome	A membrane-bound organelle that envelops particles of magnetic iron minerals in magnetotactic bacteria. Magnetosomes form linear chains that align along the cellular motility axis at midcell and function in bacterial navigation along the Earth's magnetic field. They are formed by invagination of the cell inner membrane; in some species they remain connected to the inner membrane, in others they pinch off to form independent intracellular vesicles.	tmpzr1t_l9r_go_relaxed.owl								kmv	2019-05-30T17:31:21Z					cellular_component											owl:Class	
GO:0002605	biolink:NamedThing	negative regulation of dendritic cell antigen processing and presentation	Any process that stops, prevents, or reduces the frequency, rate, or extent of dendritic cell antigen processing and presentation.	tmpzr1t_l9r_go_relaxed.owl	inhibition of dendritic cell antigen processing and presentation|down regulation of dendritic cell antigen processing and presentation|down-regulation of dendritic cell antigen processing and presentation|downregulation of dendritic cell antigen processing and presentation													biological_process											owl:Class	
GO:1900177	biolink:NamedThing	regulation of aflatoxin biosynthetic process	Any process that modulates the frequency, rate or extent of aflatoxin biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of aflatoxin synthesis|regulation of aflatoxin anabolism|regulation of aflatoxin formation|regulation of aflatoxin biosynthesis							di	2012-03-09T11:23:35Z					biological_process											owl:Class	
GO:0071413	biolink:NamedThing	cellular response to hydroxyisoflavone	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydroxyisoflavone stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-12-14T03:10:09Z					biological_process											owl:Class	
GO:0010685	biolink:NamedThing	tetracyclic triterpenoid metabolic process	The chemical reactions and pathways involving tetracyclic triterpenoid compounds, terpenoids with six isoprene units and 4 carbon rings.	tmpzr1t_l9r_go_relaxed.owl	tetracyclic triterpenoid metabolism													biological_process											owl:Class	
GO:0071303	biolink:NamedThing	cellular response to vitamin B3	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin B3 stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to nicotinamide|cellular response to niacin							mah	2009-12-10T04:35:04Z					biological_process											owl:Class	
GO:0048848	biolink:NamedThing	neurohypophysis morphogenesis	The process in which the anatomical structures of the neurohypophysis are generated and organized. The neurohypophysis is the part of the pituitary gland that secretes hormones involved in blood pressure regulation.	tmpzr1t_l9r_go_relaxed.owl	posterior pituitary gland morphogenesis|posterior pituitary morphogenesis|neurophysis morphogenesis													biological_process											owl:Class	
GO:0022612	biolink:NamedThing	gland morphogenesis	The process in which the anatomical structures of a gland are generated and organized.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0035381	biolink:NamedThing	ATP-gated ion channel activity	Enables the transmembrane transfer of an ion by a channel that opens when ATP has been bound by the channel complex or one of its constituent parts.	tmpzr1t_l9r_go_relaxed.owl								bf	2010-03-18T01:21:45Z					molecular_function											owl:Class	
GO:0015075	biolink:NamedThing	ion transmembrane transporter activity	Enables the transfer of an ion from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	ion transporter activity													molecular_function											owl:Class	
GO:0006611	biolink:NamedThing	protein export from nucleus	The directed movement of a protein from the nucleus into the cytoplasm.	tmpzr1t_l9r_go_relaxed.owl	protein transport from nucleus to cytoplasm|copper-induced protein export from nucleus|protein-nucleus export|protein export from cell nucleus|protein export out of nucleus											GO:0097349		biological_process											owl:Class	
GO:0008558	biolink:NamedThing	ABC-type guanine transporter activity	Catalyses the reaction: ATP + H2O + guanine(out) = ADP + phosphate + guanine(in).	tmpzr1t_l9r_go_relaxed.owl	ATP-dependent guanine transmembrane transporter activity|ATPase-coupled guanine transmembrane transporter activity|guanine ABC transporter|guanine-transporting ATPase activity				EC:7.6.2.6|RHEA:20832|MetaCyc:3.6.3.37-RXN									molecular_function											owl:Class	
GO:0018509	biolink:NamedThing	cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase activity	Catalysis of the reaction: cis-3-phenylcyclohexa-3,5-diene-1,2-diol + NAD+ = biphenyl-2,3-diol + NADH + H+.	tmpzr1t_l9r_go_relaxed.owl	2,3-dihydro-2,3-dihydroxybiphenyl dehydrogenase activity|cis-3-phenylcyclohexa-3,5-diene-1,2-diol:NAD+ oxidoreductase activity|biphenyl-2,3-dihydro-2,3-diol dehydrogenase activity				RHEA:17033|MetaCyc:1.3.1.56-RXN|UM-BBD_enzymeID:e0134|EC:1.3.1.56									molecular_function											owl:Class	
GO:0019403	biolink:NamedThing	galactitol biosynthetic process	The chemical reactions and pathways resulting in the formation of galactitol, the hexitol derived by the reduction of the aldehyde group of either D- or L-galactose.	tmpzr1t_l9r_go_relaxed.owl	galactitol formation|galactitol anabolism|galactitol biosynthesis|galactitol synthesis													biological_process											owl:Class	
GO:0019406	biolink:NamedThing	hexitol biosynthetic process	The chemical reactions and pathways resulting in the formation of hexitols, any alditol with a chain of six carbon atoms in the molecule.	tmpzr1t_l9r_go_relaxed.owl	hexitol formation|hexitol anabolism|hexitol synthesis|hexitol biosynthesis													biological_process											owl:Class	
GO:0032749	biolink:NamedThing	positive regulation of interleukin-25 production	Any process that activates or increases the frequency, rate, or extent of interleukin-25 production.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of interleukin-25 production|up regulation of interleukin-25 production|positive regulation of interleukin-25 biosynthetic process|stimulation of interleukin-25 production|positive regulation of interleukin-25 secretion|upregulation of interleukin-25 production|activation of interleukin-25 production|positive regulation of IL-25 production							bc	2019-12-09T16:51:44Z			GO:0045537|GO:0150150		biological_process											owl:Class	
GO:0050891	biolink:NamedThing	multicellular organismal water homeostasis	Any process involved in the maintenance of an internal steady state of water within a tissue, organ, or a multicellular organism.	tmpzr1t_l9r_go_relaxed.owl	body fluid osmoregulation													biological_process											owl:Class	
GO:0030104	biolink:NamedThing	water homeostasis	Any process involved in the maintenance of an internal steady state of water within an organism or cell.	tmpzr1t_l9r_go_relaxed.owl	osmoregulation|regulation of osmotic pressure				Wikipedia:Osmoregulation							GO:0018987		biological_process											owl:Class	
GO:0097216	biolink:NamedThing	guanosine tetraphosphate binding	Binding to guanosine tetraphosphate (5'-ppGpp-3'), a guanosine bisphosphate having diphosphate groups at both the 3' and 5'-positions.	tmpzr1t_l9r_go_relaxed.owl	5'-ppGpp-3' binding							pr	2012-01-13T08:35:50Z					molecular_function											owl:Class	
GO:0032561	biolink:NamedThing	guanyl ribonucleotide binding	Binding to a guanyl ribonucleotide, any compound consisting of guanosine esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose moiety.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1905688	biolink:NamedThing	negative regulation of diacylglycerol kinase activity	Any process that stops, prevents or reduces the frequency, rate or extent of diacylglycerol kinase activity.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of ATP:diacylglycerol phosphotransferase activity|down regulation of diacylglycerol:ATP kinase activity|downregulation of diglyceride kinase activity|downregulation of 1,2-diacylglycerol kinase (phosphorylating)|negative regulation of ATP:1,2-diacylglycerol 3-phosphotransferase activity|negative regulation of diglyceride kinase activity|inhibition of ATP:diacylglycerol phosphotransferase activity|down regulation of ATP:diacylglycerol phosphotransferase activity|inhibition of arachidonoyl-specific diacylglycerol kinase activity|inhibition of diacylglycerol kinase activity|down-regulation of DGK activity|negative regulation of arachidonoyl-specific diacylglycerol kinase activity|inhibition of DGK activity|down regulation of DG kinase activity|down-regulation of diglyceride kinase activity|down-regulation of sn-1,2-diacylglycerol kinase activity|down-regulation of diacylglycerol:ATP kinase activity|down regulation of ATP:1,2-diacylglycerol 3-phosphotransferase activity|down regulation of 1,2-diacylglycerol kinase (phosphorylating)|down regulation of diglyceride kinase activity|down regulation of sn-1,2-diacylglycerol kinase activity|downregulation of DG kinase activity|inhibition of CTP:diacylglycerol kinase activity|negative regulation of 1,2-diacylglycerol kinase activity|negative regulation of diacylglycerol:ATP kinase activity|inhibition of DG kinase activity|negative regulation of CTP:diacylglycerol kinase activity|down regulation of 1,2-diacylglycerol kinase activity|down-regulation of DG kinase activity|down-regulation of arachidonoyl-specific diacylglycerol kinase activity|down regulation of arachidonoyl-specific diacylglycerol kinase activity|inhibition of diacylglycerol:ATP kinase activity|downregulation of diacylglycerol kinase activity|down-regulation of CTP:diacylglycerol kinase activity|inhibition of ATP:1,2-diacylglycerol 3-phosphotransferase activity|negative regulation of sn-1,2-diacylglycerol kinase activity|downregulation of DGK activity|negative regulation of 1,2-diacylglycerol kinase (phosphorylating)|downregulation of 1,2-diacylglycerol kinase activity|negative regulation of DG kinase activity|down regulation of diacylglycerol kinase activity|inhibition of 1,2-diacylglycerol kinase (phosphorylating)|downregulation of CTP:diacylglycerol kinase activity|inhibition of 1,2-diacylglycerol kinase activity|inhibition of sn-1,2-diacylglycerol kinase activity|down-regulation of ATP:diacylglycerol phosphotransferase activity|negative regulation of DGK activity|downregulation of sn-1,2-diacylglycerol kinase activity|down regulation of CTP:diacylglycerol kinase activity|down-regulation of 1,2-diacylglycerol kinase activity|downregulation of diacylglycerol:ATP kinase activity|down-regulation of 1,2-diacylglycerol kinase (phosphorylating)|down-regulation of ATP:1,2-diacylglycerol 3-phosphotransferase activity|downregulation of arachidonoyl-specific diacylglycerol kinase activity|inhibition of diglyceride kinase activity|downregulation of ATP:1,2-diacylglycerol 3-phosphotransferase activity|down regulation of DGK activity|downregulation of ATP:diacylglycerol phosphotransferase activity|down-regulation of diacylglycerol kinase activity							bc	2016-11-14T12:26:18Z					biological_process											owl:Class	
GO:1905687	biolink:NamedThing	regulation of diacylglycerol kinase activity	Any process that modulates the frequency, rate or extent of diacylglycerol kinase activity.	tmpzr1t_l9r_go_relaxed.owl	regulation of diglyceride kinase activity|regulation of 1,2-diacylglycerol kinase (phosphorylating)|regulation of ATP:1,2-diacylglycerol 3-phosphotransferase activity|regulation of DG kinase activity|regulation of DGK activity|regulation of CTP:diacylglycerol kinase activity|regulation of diacylglycerol:ATP kinase activity|regulation of 1,2-diacylglycerol kinase activity|regulation of sn-1,2-diacylglycerol kinase activity|regulation of arachidonoyl-specific diacylglycerol kinase activity|regulation of ATP:diacylglycerol phosphotransferase activity							bc	2016-11-14T12:26:11Z					biological_process											owl:Class	
GO:1900966	biolink:NamedThing	negative regulation of methanophenazine metabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of methanophenazine metabolic process.	tmpzr1t_l9r_go_relaxed.owl	inhibition of methanophenazine metabolism|down regulation of methanophenazine metabolism|down regulation of methanophenazine metabolic process|downregulation of methanophenazine metabolic process|down-regulation of methanophenazine metabolic process|negative regulation of methanophenazine metabolism|downregulation of methanophenazine metabolism|down-regulation of methanophenazine metabolism|inhibition of methanophenazine metabolic process							tt	2012-06-14T03:55:49Z					biological_process											owl:Class	
GO:1900965	biolink:NamedThing	regulation of methanophenazine metabolic process	Any process that modulates the frequency, rate or extent of methanophenazine metabolic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of methanophenazine metabolism							tt	2012-06-14T03:55:26Z					biological_process											owl:Class	
GO:1904575	biolink:NamedThing	positive regulation of selenocysteine insertion sequence binding	Any process that activates or increases the frequency, rate or extent of selenocysteine insertion sequence binding.	tmpzr1t_l9r_go_relaxed.owl	activation of selenocysteine insertion sequence binding|up-regulation of selenocysteine insertion sequence binding|activation of SECIS binding|upregulation of selenocysteine insertion sequence binding|up regulation of selenocysteine insertion sequence binding|positive regulation of SECIS binding|up-regulation of SECIS binding|up regulation of SECIS binding|upregulation of SECIS binding							sl	2015-08-19T17:51:21Z					biological_process											owl:Class	
GO:0002308	biolink:NamedThing	CD8-positive, alpha-beta cytotoxic T cell differentiation	The process in which a precursor cell type acquires the specialized features of a CD8-positive, alpha-beta cytotoxic T cell.	tmpzr1t_l9r_go_relaxed.owl	CD8-positive, alpha-beta cytotoxic T lymphocyte differentiation|CD8-positive, alpha-beta cytotoxic T-lymphocyte differentiation|CD8-positive, alpha-beta cytotoxic T-cell differentiation|CD8-positive, alpha-beta cytotoxic T cell development					Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.								biological_process											owl:Class	
GO:0045065	biolink:NamedThing	cytotoxic T cell differentiation	The process in which a relatively unspecialized T cell acquires specialized features of a cytotoxic T cell.	tmpzr1t_l9r_go_relaxed.owl	cytotoxic T cell development|cytotoxic T-cell selection|cytotoxic T-lymphocyte selection|cytotoxic T lymphocyte selection					Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.								biological_process											owl:Class	
GO:0002475	biolink:NamedThing	antigen processing and presentation via MHC class Ib	The process in which an antigen-presenting cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC class Ib protein complex. Class Ib here refers to non-classical class I molecules, such as those of the CD1 or HLA-E gene families.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0043005	biolink:NamedThing	neuron projection	A prolongation or process extending from a nerve cell, e.g. an axon or dendrite.	tmpzr1t_l9r_go_relaxed.owl	nerve fiber|neuronal cell projection|neurite|neuron protrusion|neuron process				NIF_Subcellular:sao867568886									cellular_component											owl:Class	
GO:0043872	biolink:NamedThing	lysine:cadaverine antiporter activity	Catalysis of the reaction: lysine(out) + cadaverine(in) = lysine(in) + cadaverine(out).	tmpzr1t_l9r_go_relaxed.owl	cadaverine:lysine antiporter activity|cadaverine transmembrane transporter activity|lysine/cadaverine antiporter activity|lysine-cadaverine antiporter activity											GO:0015490|GO:0015497		molecular_function											owl:Class	
GO:0050898	biolink:NamedThing	nitrile metabolic process	The chemical reactions and pathways involving nitriles, an organic compound containing trivalent nitrogen attached to one carbon atom. The nitriles are named with reference to the acids produced by their decomposition; for example, hydrocyanic acid is formic nitrile, and methyl cyanide is acetic nitrile.	tmpzr1t_l9r_go_relaxed.owl	nitrile metabolism													biological_process											owl:Class	
GO:0015147	biolink:NamedThing	L-arabinose transmembrane transporter activity	Enables the transfer of L-arabinose from one side of a membrane to the other. Arabinose occurs free, for example in the heartwood of many conifers and in the combined states, in both furanose and pyranose forms, as a constituent of various plant hemicelluloses, bacterial polysaccharides, etc.	tmpzr1t_l9r_go_relaxed.owl	L-arabinose/beta-D-thiogalactopyranoside:hydrogen antiporter activity													molecular_function											owl:Class	
GO:0042900	biolink:NamedThing	arabinose transmembrane transporter activity	Enables the transfer of arabinose, a pentose monosaccharide that occurs in both D and L configurations, and as a polymer, from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0033718	biolink:NamedThing	pyranose dehydrogenase (acceptor) activity	Catalysis of the reactions: pyranose + acceptor = 2-dehydropyranose (or 3-dehydropyranose or 2,3-didehydropyranose) + reduced acceptor, and a pyranoside + acceptor = a 3-dehydropyranoside (or 3,4-didehydropyranoside) + reduced acceptor.	tmpzr1t_l9r_go_relaxed.owl	pyranose-quinone oxidoreductase activity|PDH|pyranose:acceptor oxidoreductase activity|pyranose dehydrogenase activity|quinone-dependent pyranose dehydrogenase activity				MetaCyc:RXN-7965|MetaCyc:RXN-7962|MetaCyc:RXN-7966|EC:1.1.99.29|MetaCyc:RXN-7961|MetaCyc:RXN-7963									molecular_function											owl:Class	
GO:1902599	biolink:NamedThing	sulfathiazole transmembrane transport	The directed movement of sulfathiazole across a membrane.	tmpzr1t_l9r_go_relaxed.owl	sulfathiazole transport|sulphathiazole transport							pr	2013-12-20T11:08:28Z			GO:0015906		biological_process											owl:Class	
GO:0002509	biolink:NamedThing	central tolerance induction to self antigen	Tolerance induction in the central lymphoid organs directed at self antigens.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0002508	biolink:NamedThing	central tolerance induction	Tolerance induction in the central lymphoid organs: the thymus and bone marrow.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0050971	biolink:NamedThing	detection of mechanical stimulus involved in magnetoreception	The series of events involved in magnetoception in which a mechanical stimulus is received and converted into a molecular signal. The stimulus is in the form of torque on particles such as magnetite which respond to a magnetic field.	tmpzr1t_l9r_go_relaxed.owl	magnetoreception, detection of mechanical stimulus|magnetoception, sensory transduction of mechanical stimulus|magnetoreception, sensory detection of mechanical stimulus|sensory transduction of mechanical stimulus during magnetoreception|magnetoreception, sensory transduction of mechanical stimulus|sensory detection of mechanical stimulus during magnetoreception													biological_process											owl:Class	
GO:0003227	biolink:NamedThing	right ventricular trabecular myocardium morphogenesis	The process in which the anatomical structures of the right ventricular myocardium are generated and organized.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-10-13T10:50:59Z					biological_process											owl:Class	
GO:0003221	biolink:NamedThing	right ventricular cardiac muscle tissue morphogenesis	The process in which the anatomical structures of the right cardiac ventricle muscle are generated and organized.	tmpzr1t_l9r_go_relaxed.owl	right ventricle myocardium morphogenesis							dph	2009-10-13T10:26:33Z					biological_process											owl:Class	
GO:0015816	biolink:NamedThing	glycine transport	The directed movement of glycine, aminoethanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0015804	biolink:NamedThing	neutral amino acid transport	The directed movement of neutral amino acids, amino acids with no net charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0009066	biolink:NamedThing	aspartate family amino acid metabolic process	The chemical reactions and pathways involving amino acids of the aspartate family, comprising asparagine, aspartate, lysine, methionine and threonine.	tmpzr1t_l9r_go_relaxed.owl	aspartate family amino acid metabolism													biological_process											owl:Class	
GO:1900059	biolink:NamedThing	positive regulation of sulfate assimilation	Any process that activates or increases the frequency, rate or extent of sulfate assimilation.	tmpzr1t_l9r_go_relaxed.owl	up regulation of sulfate assimilation|activation of sulfate assimilation|upregulation of sulfate assimilation|up-regulation of sulphate assimilation, phosphoadenylyl sulphate reduction by an oxidoreductase, acting on sulphur group of donors, NAD or NADP as acceptor|up-regulation of sulfate assimilation, phosphoadenylyl sulfate reduction by an oxidoreductase, acting on sulfur group of donors, NAD or NADP as acceptor|up-regulation of sulfate assimilation|activation of sulphate assimilation|upregulation of sulphate assimilation|activation of sulphate assimilation, phosphoadenylyl sulphate reduction by an oxidoreductase, acting on sulphur group of donors, NAD or NADP as acceptor|up regulation of sulphate assimilation|upregulation of sulfate assimilation, phosphoadenylyl sulfate reduction by an oxidoreductase, acting on sulfur group of donors, NAD or NADP as acceptor|positive regulation of sulphate assimilation, phosphoadenylyl sulphate reduction by an oxidoreductase, acting on sulphur group of donors, NAD or NADP as acceptor|up regulation of sulfate assimilation, phosphoadenylyl sulfate reduction by an oxidoreductase, acting on sulfur group of donors, NAD or NADP as acceptor|positive regulation of sulphate assimilation|up regulation of sulphate assimilation, phosphoadenylyl sulphate reduction by an oxidoreductase, acting on sulphur group of donors, NAD or NADP as acceptor|positive regulation of sulfate assimilation, phosphoadenylyl sulfate reduction by an oxidoreductase, acting on sulfur group of donors, NAD or NADP as acceptor|up-regulation of sulphate assimilation|activation of sulfate assimilation, phosphoadenylyl sulfate reduction by an oxidoreductase, acting on sulfur group of donors, NAD or NADP as acceptor|upregulation of sulphate assimilation, phosphoadenylyl sulphate reduction by an oxidoreductase, acting on sulphur group of donors, NAD or NADP as acceptor							dph	2012-01-25T03:14:47Z					biological_process											owl:Class	
GO:1900058	biolink:NamedThing	regulation of sulfate assimilation	Any process that modulates the frequency, rate or extent of sulfate assimilation.	tmpzr1t_l9r_go_relaxed.owl	regulation of sulphate assimilation, phosphoadenylyl sulphate reduction by an oxidoreductase, acting on sulphur group of donors, NAD or NADP as acceptor|regulation of sulphate assimilation|regulation of sulfate assimilation, phosphoadenylyl sulfate reduction by an oxidoreductase, acting on sulfur group of donors, NAD or NADP as acceptor							dph	2012-01-25T03:14:40Z					biological_process											owl:Class	
GO:0006885	biolink:NamedThing	regulation of pH	Any process involved in the maintenance of an internal equilibrium of hydrogen ions, thereby modulating the internal pH, within an organism or cell.	tmpzr1t_l9r_go_relaxed.owl	hydrogen ion homeostasis													biological_process											owl:Class	
GO:0055067	biolink:NamedThing	monovalent inorganic cation homeostasis	Any process involved in the maintenance of an internal steady state of monovalent inorganic cations within an organism or cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0009089	biolink:NamedThing	lysine biosynthetic process via diaminopimelate	The chemical reactions and pathways resulting in the formation of lysine, via the intermediate diaminopimelate.	tmpzr1t_l9r_go_relaxed.owl	diaminopimelate pathway|diaminopimelic acid pathway|lysine formation via diaminopimelate|lysine biosynthetic process via diaminopimelic acid|lysine synthesis via diaminopimelate|lysine anabolism via diaminopimelate|lysine biosynthesis via diaminopimelic acid													biological_process											owl:Class	
GO:0009085	biolink:NamedThing	lysine biosynthetic process	The chemical reactions and pathways resulting in the formation of lysine, 2,6-diaminohexanoic acid.	tmpzr1t_l9r_go_relaxed.owl	lysine biosynthesis|lysine anabolism|lysine synthesis|lysine formation				MetaCyc:PWY-5097									biological_process											owl:Class	
GO:0060715	biolink:NamedThing	syncytiotrophoblast cell differentiation involved in labyrinthine layer development	The process in which a chorionic trophoblast cell acquires specialized features of a syncytiotrophoblast of the labyrinthine layer of the placenta.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-06-11T08:56:18Z					biological_process											owl:Class	
GO:0060706	biolink:NamedThing	cell differentiation involved in embryonic placenta development	The process in which a relatively unspecialized cell acquires specialized features of the embryonic placenta.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-06-09T10:26:42Z					biological_process											owl:Class	
GO:0060319	biolink:NamedThing	primitive erythrocyte differentiation	Erythrocyte differentiation which occurs as part of the process of primitive hemopoiesis.	tmpzr1t_l9r_go_relaxed.owl	primitive RBC differentiation|primitive erythropoiesis|primitive red blood cell differentiation													biological_process											owl:Class	
GO:0000750	biolink:NamedThing	pheromone-dependent signal transduction involved in conjugation with cellular fusion	A signal transduction process resulting in the relay, amplification or dampening of a signal generated in response to pheromone exposure in organisms that undergo conjugation with cellular fusion. An example of this process is found in Saccharomyces cerevisiae.	tmpzr1t_l9r_go_relaxed.owl	transduction of mating signal											GO:0007330|GO:0030454		biological_process											owl:Class	
GO:0032005	biolink:NamedThing	signal transduction involved in positive regulation of conjugation with cellular fusion	The series of molecular signals that bring about the relay, amplification or dampening of a signal generated in response to a cue, such as starvation or pheromone exposure, in organisms that undergo conjugation with cellular fusion.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0019346	biolink:NamedThing	transsulfuration	The interconversion of homocysteine and cysteine via cystathionine. In contrast with enteric bacteria and mammals, Saccharomyces cerevisiae has two transsulfuration pathways employing two separate sets of enzymes.	tmpzr1t_l9r_go_relaxed.owl	transsulphuration|homocysteine-cysteine interconversion				MetaCyc:PWY-801|Wikipedia:Transsulfuration_pathway									biological_process											owl:Class	
GO:0099152	biolink:NamedThing	regulation of neurotransmitter receptor transport, endosome to postsynaptic membrane	Any process that modulates the frequency, rate or extent of the directed movement of neurotransmitter receptor from the postsynaptic endosome to the postsynaptic membrane in transport vesicles.	tmpzr1t_l9r_go_relaxed.owl								dos	2017-08-25T15:01:11Z					biological_process											owl:Class	
GO:0002591	biolink:NamedThing	positive regulation of antigen processing and presentation of peptide antigen via MHC class I	Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class I.	tmpzr1t_l9r_go_relaxed.owl	stimulation of antigen processing and presentation of peptide antigen via MHC class I|up-regulation of antigen processing and presentation of peptide antigen via MHC class I|up regulation of antigen processing and presentation of peptide antigen via MHC class I|positive regulation of peptide antigen processing and presentation via MHC class I|activation of antigen processing and presentation of peptide antigen via MHC class I|upregulation of antigen processing and presentation of peptide antigen via MHC class I													biological_process											owl:Class	
GO:0032230	biolink:NamedThing	positive regulation of synaptic transmission, GABAergic	Any process that activates, maintains or increases the frequency, rate or extent of GABAergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter gamma-aminobutyric acid (GABA).	tmpzr1t_l9r_go_relaxed.owl	upregulation of synaptic transmission, GABAergic|activation of synaptic transmission, GABAergic|up regulation of synaptic transmission, GABAergic|up-regulation of synaptic transmission, GABAergic|stimulation of synaptic transmission, GABAergic													biological_process											owl:Class	
GO:0032228	biolink:NamedThing	regulation of synaptic transmission, GABAergic	Any process that modulates the frequency, rate or extent of GABAergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter gamma-aminobutyric acid (GABA).	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0051312	biolink:NamedThing	chromosome decondensation	The alteration of chromosome structure from the condensed form to a relaxed disperse form.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0051276	biolink:NamedThing	chromosome organization	A process that is carried out at the cellular level that results in the assembly, arrangement of constituent parts, or disassembly of chromosomes, structures composed of a very long molecule of DNA and associated proteins that carries hereditary information. This term covers covalent modifications at the molecular level as well as spatial relationships among the major components of a chromosome.	tmpzr1t_l9r_go_relaxed.owl	maintenance of genome integrity|nuclear genome maintenance|chromosome organisation|chromosome organization and biogenesis											GO:0007001|GO:0051277		biological_process											owl:Class	
GO:0007385	biolink:NamedThing	specification of segmental identity, abdomen	The specification of the characteristic structures of the abdominal segments following establishment of segment boundaries. Identity is considered to be the aggregate of characteristics by which a structure is recognized.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0035292	biolink:NamedThing	specification of segmental identity, trunk	The specification of the characteristic structures of trunk segments, following establishment of segment boundaries. In Drosophila, the trunk segments include thoracic segments and abdominal segments A1 to A8. Identity is considered to be the aggregate of characteristics by which a structure is recognized.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0003376	biolink:NamedThing	sphingosine-1-phosphate receptor signaling pathway	A series of molecular signals initiated by the sphingolipid sphingosine-1-phosphate (S1P) binding to a receptor on the surface of the cell, and which proceeds with the activated receptor transmitting the signal by promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The pathway ends with regulation of a downstream cellular process, e.g. transcription.	tmpzr1t_l9r_go_relaxed.owl	sphingolipid signalling pathway|sphingolipid signaling pathway|S1P-activated G-protein coupled receptor signaling pathway|S1P-activated GPCR signaling pathway|S1P-stimulated signal transduction pathway|S1P receptor signaling pathway|S1P signaling pathway	https://github.com/geneontology/go-ontology/issues/15822						dph	2009-12-09T06:30:12Z			GO:0001789		biological_process											owl:Class	
GO:0007186	biolink:NamedThing	G protein-coupled receptor signaling pathway	A series of molecular signals that proceeds with an activated receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction, or for basal GPCR signaling the pathway begins with the receptor activating its G protein in the absence of an agonist, and ends with regulation of a downstream cellular process, e.g. transcription.  The pathway can start from the plasma membrane, Golgi or nuclear membrane.	tmpzr1t_l9r_go_relaxed.owl	dimeric G-protein coupled receptor signalling pathway|GPCR signaling pathway|G-protein coupled receptor protein signal transduction|dimeric G-protein coupled receptor signaling pathway|GPCR signalling pathway|G protein coupled receptor protein signaling pathway|G-protein coupled receptor protein signaling pathway|G-protein coupled receptor signaling pathway via GPCR dimer|G-protein coupled receptor signalling pathway|G protein coupled receptor protein signalling pathway|G-protein-coupled receptor protein signalling pathway											GO:0038042		biological_process											owl:Class	
GO:0030512	biolink:NamedThing	negative regulation of transforming growth factor beta receptor signaling pathway	Any process that stops, prevents, or reduces the frequency, rate or extent of any TGF-beta receptor signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	downregulation of transforming growth factor beta receptor signaling pathway|down regulation of transforming growth factor beta receptor signaling pathway|negative regulation of TGFbeta receptor signaling pathway|inhibition of transforming growth factor beta receptor signaling pathway|negative regulation of transforming growth factor beta receptor signalling pathway|down-regulation of transforming growth factor beta receptor signaling pathway|negative regulation of TGF-beta receptor signaling pathway													biological_process											owl:Class	
GO:1900373	biolink:NamedThing	positive regulation of purine nucleotide biosynthetic process	Any process that activates or increases the frequency, rate or extent of purine nucleotide biosynthetic processes.	tmpzr1t_l9r_go_relaxed.owl	upregulation of purine nucleotide biosynthesis|positive regulation of purine nucleotide formation|activation of purine nucleotide synthesis|upregulation of purine nucleotide synthesis|up regulation of purine nucleotide anabolism|up regulation of purine nucleotide biosynthetic process|up-regulation of purine nucleotide biosynthesis|up regulation of purine nucleotide formation|up-regulation of purine nucleotide synthesis|positive regulation of purine nucleotide synthesis|activation of purine nucleotide biosynthetic process|activation of purine nucleotide anabolism|positive regulation of purine nucleotide anabolism|up-regulation of purine nucleotide formation|upregulation of purine nucleotide biosynthetic process|activation of purine nucleotide biosynthesis|up regulation of purine nucleotide biosynthesis|positive regulation of purine nucleotide biosynthesis|upregulation of purine nucleotide anabolism|up-regulation of purine nucleotide anabolism|up-regulation of purine nucleotide biosynthetic process|activation of purine nucleotide formation|upregulation of purine nucleotide formation|up regulation of purine nucleotide synthesis							krc	2012-04-17T12:32:37Z					biological_process											owl:Class	
GO:0007144	biolink:NamedThing	female meiosis I	The cell cycle process in which the first meiotic division occurs in the female germline.	tmpzr1t_l9r_go_relaxed.owl	female meiosis I nuclear division													biological_process											owl:Class	
GO:0007143	biolink:NamedThing	female meiotic nuclear division	A cell cycle process by which the cell nucleus divides as part of a meiotic cell cycle in the female germline.	tmpzr1t_l9r_go_relaxed.owl	female meiotic division|female meiosis					Note that female germ lines can be found in female or hermaphroditic organisms, so this term can be used to annotate gene products from hermaphrodites such as those of C. elegans. See also the biological process term 'meiotic nuclear division; GO:0140013'.								biological_process											owl:Class	
GO:0075222	biolink:NamedThing	sporangium germination	The physiological, developmental and morphological changes that occur in a symbiont sporangium following release from dormancy up to the earliest signs of growth. A sporangium is a structure producing and containing spores.	tmpzr1t_l9r_go_relaxed.owl	germination of symbiont sporangium on or near host|direct germination on or near host|symbiont sporangium germination on or near host|sporangium germination on or near host													biological_process											owl:Class	
GO:0043582	biolink:NamedThing	sporangium development	The process whose specific outcome is the progression of the sporangium over time, from its formation to the mature structure. A sporangium is a structure producing and containing spores.	tmpzr1t_l9r_go_relaxed.owl	sporangia development													biological_process											owl:Class	
GO:0090336	biolink:NamedThing	positive regulation of brown fat cell differentiation	Any process that increases the rate, frequency, or extent of brown fat cell differentiation. Brown fat cell differentiation is the process in which a relatively unspecialized cell acquires specialized features of a brown adipocyte, an animal connective tissue cell involved in adaptive thermogenesis. Brown adipocytes contain multiple small droplets of triglycerides and a high number of mitochondria.	tmpzr1t_l9r_go_relaxed.owl								tb	2010-06-01T03:19:26Z					biological_process											owl:Class	
GO:0045600	biolink:NamedThing	positive regulation of fat cell differentiation	Any process that activates or increases the frequency, rate or extent of adipocyte differentiation.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of adipocyte cell differentiation|upregulation of fat cell differentiation|stimulation of fat cell differentiation|up-regulation of fat cell differentiation|activation of fat cell differentiation|up regulation of fat cell differentiation|positive regulation of adipocyte differentiation													biological_process											owl:Class	
GO:0033076	biolink:NamedThing	isoquinoline alkaloid metabolic process	The chemical reactions and pathways involving isoquinoline alkaloids, alkaloid compounds that contain bicyclic N-containing aromatic rings and are derived from a 3,4-dihydroxytyramine (dopamine) precursor that undergoes a Schiff base addition with aldehydes of different origin.	tmpzr1t_l9r_go_relaxed.owl	ipecac alkaloid metabolism|isoquinoline alkaloid metabolism													biological_process											owl:Class	
GO:0120302	biolink:NamedThing	background adaptation	Any process in which an organism changes its pigmentation (lightening in response to a brighter environment or darkening in response to a dimmer environment) in response to a change in light intensity.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/20524						krc	2021-02-09T18:11:11Z					biological_process											owl:Class	
GO:0033240	biolink:NamedThing	positive regulation of cellular amine metabolic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving amines.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of amine metabolism													biological_process											owl:Class	
GO:1903826	biolink:NamedThing	L-arginine transmembrane transport	The directed movement of L-arginine across a membrane.	tmpzr1t_l9r_go_relaxed.owl	L-arginine transport|L-arginine uptake|arginine transport|L-arginine import|arginine transmembrane transport	https://github.com/geneontology/go-ontology/issues/22228						vw	2015-01-20T10:38:15Z			GO:1902023|GO:0043091|GO:0015809|GO:1903400		biological_process											owl:Class	
GO:0035774	biolink:NamedThing	positive regulation of insulin secretion involved in cellular response to glucose stimulus	Any process that increases the frequency, rate or extent of the regulated release of insulin that contributes to the response of a cell to glucose.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of insulin secretion in response to glucose							bf	2011-04-01T01:49:09Z					biological_process											owl:Class	
GO:0061178	biolink:NamedThing	regulation of insulin secretion involved in cellular response to glucose stimulus	Any process that modulates the frequency, rate or extent of the regulated release of insulin that contributes to the response of a cell to glucose.	tmpzr1t_l9r_go_relaxed.owl	regulation of insulin secretion in response to glucose							dph	2010-07-13T09:38:42Z					biological_process											owl:Class	
GO:0090035	biolink:NamedThing	positive regulation of chaperone-mediated protein complex assembly	Any process that increases the frequency, rate, or extent of chaperone-mediated protein complex assembly. Chaperone-mediated protein complex assembly is the aggregation, arrangement and bonding together of a set of components to form a protein complex, mediated by chaperone molecules that do not form part of the finished complex.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-08-03T11:15:25Z					biological_process											owl:Class	
GO:0050164	biolink:NamedThing	oxoglutarate dehydrogenase (NADP+) activity	Catalysis of the reaction: 2-oxoglutarate + CoA + NADP(+) = CO(2) + NADPH + succinyl-CoA.	tmpzr1t_l9r_go_relaxed.owl	2-oxoglutarate:NADP+ 2-oxidoreductase (CoA-succinylating)				KEGG_REACTION:R00265|MetaCyc:OXOGLUTARATE-DEHYDROGENASE-NADP+-RXN|RHEA:21400|EC:1.2.1.52									molecular_function											owl:Class	
GO:0034601	biolink:NamedThing	oxoglutarate dehydrogenase [NAD(P)+] activity	Catalysis of the reaction: 2-oxoglutarate + CoA + NAD(P)+ = succinyl-CoA + CO2 + NAD(P)H.	tmpzr1t_l9r_go_relaxed.owl					EC:1.2.1.52									molecular_function											owl:Class	
GO:0046007	biolink:NamedThing	negative regulation of activated T cell proliferation	Any process that stops, prevents or reduces the rate or extent of activated T cell proliferation.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of activated T-cell proliferation|down regulation of activated T cell proliferation|down-regulation of activated T cell proliferation|negative regulation of activated T lymphocyte proliferation|downregulation of activated T cell proliferation|negative regulation of activated T-lymphocyte proliferation|inhibition of activated T cell proliferation													biological_process											owl:Class	
GO:0033605	biolink:NamedThing	positive regulation of catecholamine secretion	Any process that activates or increases the frequency, rate or extent of the regulated release of a catecholamine.	tmpzr1t_l9r_go_relaxed.owl	upregulation of catecholamine secretion|stimulation of catecholamine secretion|up regulation of catecholamine secretion|up-regulation of catecholamine secretion|activation of catecholamine secretion													biological_process											owl:Class	
GO:0021642	biolink:NamedThing	trochlear nerve formation	The process that gives rise to the trochlear nerve. This process pertains to the initial formation of a structure from unspecified parts. The trochlear nerve is a motor nerve and is the only cranial nerve to exit the brain dorsally. The trochlear nerve innervates the superior oblique muscle.	tmpzr1t_l9r_go_relaxed.owl	CN IV formation|CN IV biosynthesis													biological_process											owl:Class	
GO:2000225	biolink:NamedThing	negative regulation of testosterone biosynthetic process	Any process that stops, prevents, or reduces the frequency, rate or extent of testosterone biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl								yaf	2010-11-09T10:38:37Z					biological_process											owl:Class	
GO:1901581	biolink:NamedThing	negative regulation of telomeric RNA transcription from RNA pol II promoter	Any process that stops, prevents or reduces the frequency, rate or extent of telomeric RNA transcription from RNA pol II promoter.	tmpzr1t_l9r_go_relaxed.owl	inhibition of telomeric RNA transcription from RNA pol II promoter|down regulation of telomeric RNA transcription from RNA pol II promoter|downregulation of telomeric RNA transcription from Pol II promoter|negative regulation of telomeric RNA transcription from Pol II promoter|inhibition of telomeric RNA transcription from Pol II promoter|down regulation of telomeric RNA transcription from Pol II promoter|down-regulation of telomeric RNA transcription from RNA pol II promoter|downregulation of telomeric RNA transcription from RNA pol II promoter|down-regulation of telomeric RNA transcription from Pol II promoter							al	2012-11-06T11:07:21Z					biological_process											owl:Class	
GO:1901580	biolink:NamedThing	regulation of telomeric RNA transcription from RNA pol II promoter	Any process that modulates the frequency, rate or extent of telomeric RNA transcription from RNA pol II promoter.	tmpzr1t_l9r_go_relaxed.owl	regulation of telomeric RNA transcription from Pol II promoter							al	2012-11-06T11:07:16Z					biological_process											owl:Class	
GO:0047545	biolink:NamedThing	2-hydroxyglutarate dehydrogenase activity	Catalysis of the reaction: (S)-2-hydroxyglutarate + acceptor = 2-oxoglutarate + reduced acceptor.	tmpzr1t_l9r_go_relaxed.owl	hydroxyglutaric dehydrogenase activity|(S)-2-hydroxyglutarate:(acceptor) 2-oxidoreductase|alpha-hydroxyglutarate dehydrogenase activity|L-alpha-hydroxyglutarate dehydrogenase activity|(S)-2-hydroxyglutarate:acceptor 2-oxidoreductase|alpha-hydroxyglutarate dehydrogenase (NAD+ specific)|L-alpha-hydroxyglutarate:NAD+ 2-oxidoreductase|alpha-hydroxyglutarate oxidoreductase activity				EC:1.1.99.2|RHEA:21252|MetaCyc:2-HYDROXYGLUTARATE-DEHYDROGENASE-RXN|Reactome:R-HSA-880050									molecular_function											owl:Class	
GO:0034858	biolink:NamedThing	2-hydroxybenzothiazole monooxygenase activity	Catalysis of the reaction: 2-hydroxybenzothiazole + 1/2 O2 = 2,6-dihydroxybenzothiazole.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r1291									molecular_function											owl:Class	
GO:0048332	biolink:NamedThing	mesoderm morphogenesis	The process in which the anatomical structures of the mesoderm are generated and organized.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0048729	biolink:NamedThing	tissue morphogenesis	The process in which the anatomical structures of a tissue are generated and organized.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0033103	biolink:NamedThing	protein secretion by the type VI secretion system	The process in which proteins are transferred into the extracellular milieu or directly into host cells by the type VI secretion system. Proteins secreted by this system do not require an N-terminal signal sequence.	tmpzr1t_l9r_go_relaxed.owl	type VI protein secretion system|protein secretion by the type VI protein secretion system|protein secretion by the T6SS					Note that this term represents an activity and not a cellular structure. Consider also annotating to the cellular component term 'type VI protein secretion system complex ; GO:0033104'.								biological_process											owl:Class	
GO:1901737	biolink:NamedThing	(R)-mevalonic acid biosynthetic process	The chemical reactions and pathways resulting in the formation of (R)-mevalonic acid.	tmpzr1t_l9r_go_relaxed.owl	(R)-mevalonate biosynthesis|(R)-mevalonate synthesis|(R)-mevalonic acid anabolism|(R)-mevalonate anabolism|(R)-mevalonic acid formation|(R)-mevalonic acid biosynthesis|(R)-mevalonic acid synthesis							yaf	2013-01-11T11:25:59Z					biological_process											owl:Class	
GO:1905541	biolink:NamedThing	regulation of L-arginine import across plasma membrane	Any process that modulates the frequency, rate or extent of L-arginine import across plasma membrane.	tmpzr1t_l9r_go_relaxed.owl	regulation of L-arginine import|regulation of L-arginine import into cell	https://github.com/geneontology/go-ontology/issues/22228							2014-03-31T14:30:40Z			GO:0010963|GO:1902826		biological_process											owl:Class	
GO:0022026	biolink:NamedThing	epidermal growth factor signaling pathway involved in forebrain neuron fate commitment	The series of molecular signals generated as a consequence of a epidermal growth factor receptor binding to one of its physiological ligands that contributes to the commitment of a neuroblast to a neuronal fate. The neuron will reside in the forebrain.	tmpzr1t_l9r_go_relaxed.owl	epidermal growth factor signalling pathway involved in forebrain neuron fate commitment													biological_process											owl:Class	
GO:0007173	biolink:NamedThing	epidermal growth factor receptor signaling pathway	A series of molecular signals initiated by binding of a ligand to the tyrosine kinase receptor EGFR (ERBB1) on the surface of a cell. The pathway ends with regulation of a downstream cellular process, e.g. transcription.	tmpzr1t_l9r_go_relaxed.owl	ERBB1 signaling pathway|EGF receptor signaling pathway|receptor tyrosine-protein kinase erbB-1 signaling pathway|epidermal growth factor receptor signalling pathway|EGF receptor signalling pathway|EGFR signaling pathway													biological_process											owl:Class	
GO:0030700	biolink:NamedThing	glycine reductase complex	Complex that possesses glycine reductase activity; usually comprises three subunits, of which two are selenoproteins; the subunits are typically designated selenoprotein A, selenoprotein B and protein C.	tmpzr1t_l9r_go_relaxed.owl						Note that this term represents a location and not a function; the activity possessed by this complex is mentioned in the definition for the purpose of describing and distinguishing the complex. The function possessed by this complex is represented by the molecular function term 'glycine reductase activity ; GO:0030699'.								cellular_component											owl:Class	
GO:0016241	biolink:NamedThing	regulation of macroautophagy	Any process that modulates the frequency, rate or extent of macroautophagy.	tmpzr1t_l9r_go_relaxed.owl	regulation of starvation-induced autophagy													biological_process											owl:Class	
GO:0006644	biolink:NamedThing	phospholipid metabolic process	The chemical reactions and pathways involving phospholipids, any lipid containing phosphoric acid as a mono- or diester.	tmpzr1t_l9r_go_relaxed.owl	phospholipid metabolism													biological_process											owl:Class	
GO:0034731	biolink:NamedThing	Lsm-containing SMN-Sm protein complex	An SMN-Sm protein complex formed by the association of the methylated Sm proteins B/B', D3, E, F, and G, and Lsm10 and Lsm11, with the SMN complex. This complex forms Sm cores on U7 snRNA.	tmpzr1t_l9r_go_relaxed.owl	SMN-containing protein complex													cellular_component											owl:Class	
GO:0034719	biolink:NamedThing	SMN-Sm protein complex	A protein complex formed by the association of several methylated Sm proteins with the SMN complex; the latter contains the survival motor neuron (SMN) protein and at least eight additional integral components, including the Gemin2-8 and unrip proteins; additional proteins, including galectin-1 and galectin-3, are also found in the SMN-SM complex. The SMN-Sm complex is involved in spliceosomal snRNP assembly in the cytoplasm.	tmpzr1t_l9r_go_relaxed.owl	SMN-containing protein complex					Note that this complex is sometimes referred to as the 'SMN complex', but it should not be confused with GO:0032797.								cellular_component											owl:Class	
GO:2001003	biolink:NamedThing	regulation of pectin catabolic process	Any process that modulates the frequency, rate or extent of pectin catabolic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of pectin catabolism|regulation of pectin breakdown|regulation of pectin degradation							tt	2011-08-08T03:24:01Z					biological_process											owl:Class	
GO:0032881	biolink:NamedThing	regulation of polysaccharide metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving polysaccharides.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0003886	biolink:NamedThing	DNA (cytosine-5-)-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + DNA containing cytosine = S-adenosyl-L-homocysteine + DNA containing 5-methylcytosine.	tmpzr1t_l9r_go_relaxed.owl	deoxyribonucleic methylase activity|S-adenosyl-L-methionine:DNA (cytosine-5-)-methyltransferase activity|cytosine DNA methyltransferase activity|site-specific DNA-methyltransferase (cytosine-specific) activity|DNA cytosine C5 methylase activity|DNA cytosine methylase activity|restriction-modification system activity|DNA-cytosine methyltransferase activity|DNA cytosine C(5) methylase activity|DNA-cytosine 5-methylase activity|cytosine DNA methylase activity|DNA 5-cytosine methylase activity|cytosine-specific DNA methyltransferase activity|deoxyribonucleic (cytosine-5-)-methyltransferase activity|methylphosphotriester-DNA methyltransferase activity|type II DNA methylase activity|deoxyribonucleic acid (cytosine-5-)-methyltransferase activity|cytosine 5-methyltransferase activity|modification methylase activity				MetaCyc:2.1.1.73-RXN|RHEA:13681|EC:2.1.1.37	Note that EC:2.1.1.73 was deleted from EC as the reaction is performed by DNA (cytosine-5-)-methyltransferase (EC:2.1.1.37).						GO:0008326		molecular_function											owl:Class	
GO:0009008	biolink:NamedThing	DNA-methyltransferase activity	Catalysis of the transfer of a methyl group to a DNA molecule.	tmpzr1t_l9r_go_relaxed.owl	Type II DNA methylase|DNA methyltransferase activity|deoxyribonucleic acid modification methylase activity|deoxyribonucleic acid methylase activity|deoxyribonucleate methylase activity|DNA methylase|DNA transmethylase activity|deoxyribonucleate methyltransferase activity|deoxyribonucleic acid methyltransferase activity				Reactome:R-HSA-5227490									molecular_function											owl:Class	
GO:0140683	biolink:NamedThing	histone H3-di/monomethyl-lysine-9 demethylase activity	Catalysis of the removal of a methyl group from a di or a monomethyl-lysine residue at position 9 of the histone H3 protein. This is a dioxygenase reaction that is dependent on Fe(II) and 2-oxoglutarate.	tmpzr1t_l9r_go_relaxed.owl	histone H3K9me2 demethylase activity|histone H3K9me demethylase activity	https://github.com/geneontology/go-ontology/issues/21089			EC:1.14.11.65|RHEA:60188			pg	2021-07-09T06:03:06Z					molecular_function											owl:Class	
GO:0016750	biolink:NamedThing	O-succinyltransferase activity	Catalysis of the transfer of a succinyl group to an oxygen atom on the acceptor molecule.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0150079	biolink:NamedThing	negative regulation of neuroinflammatory response	Any process that stops, prevents or reduces the frequency, rate or extent of neuroinflammatory response.	tmpzr1t_l9r_go_relaxed.owl								bc	2018-07-26T12:38:08Z					biological_process											owl:Class	
GO:1901591	biolink:NamedThing	regulation of double-strand break repair via break-induced replication	Any process that modulates the frequency, rate or extent of double-strand break repair via break-induced replication.	tmpzr1t_l9r_go_relaxed.owl								al	2012-11-07T16:37:34Z					biological_process											owl:Class	
GO:0061544	biolink:NamedThing	peptide secretion, neurotransmission	The controlled release of a peptide from a cell in which the peptide acts as a neurotransmitter.	tmpzr1t_l9r_go_relaxed.owl								dph	2013-06-25T09:10:10Z					biological_process											owl:Class	
GO:1900027	biolink:NamedThing	regulation of ruffle assembly	Any process that modulates the frequency, rate or extent of ruffle assembly.	tmpzr1t_l9r_go_relaxed.owl	regulation of membrane ruffling|regulation of membrane ruffle formation							yaf	2012-01-12T05:00:49Z					biological_process											owl:Class	
GO:0004085	biolink:NamedThing	butyryl-CoA dehydrogenase activity	Catalysis of the reaction: butanoyl-CoA + electron-transfer flavoprotein = 2-butenoyl-CoA + reduced electron-transfer flavoprotein.	tmpzr1t_l9r_go_relaxed.owl	short-chain acyl CoA dehydrogenase activity|unsaturated acyl-CoA reductase activity|short-chain-acyl-CoA dehydrogenase activity|butanoyl-CoA:acceptor 2,3-oxidoreductase activity|butyryl coenzyme A dehydrogenase activity|3-hydroxyacyl CoA reductase activity|short-chain acyl-coenzyme A dehydrogenase activity|unsaturated acyl coenzyme A reductase activity|enoyl-coenzyme A reductase activity|butyryl dehydrogenase activity|ethylene reductase activity|butanoyl-CoA:(acceptor) 2,3-oxidoreductase activity				UM-BBD_reactionID:r0013|MetaCyc:BUTYRYL-COA-DEHYDROGENASE-RXN|EC:1.3.8.1|KEGG_REACTION:R01178									molecular_function											owl:Class	
GO:0052890	biolink:NamedThing	oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces a flavin.	tmpzr1t_l9r_go_relaxed.owl					EC:1.3.8.-									molecular_function											owl:Class	
GO:0039595	biolink:NamedThing	induction by virus of catabolism of host mRNA	The process in which a virus increases the frequency, rate or extent of the breakdown of host messenger RNA (mRNA).	tmpzr1t_l9r_go_relaxed.owl	virus-mediated mRNA decay|viral induction of host mRNA decay|induction by virus of host mRNA catabolic process|induction of host mRNA decay|promotion of host mRNA degradation				VZ:901			bf	2012-07-04T03:14:04Z					biological_process											owl:Class	
GO:0039656	biolink:NamedThing	modulation by virus of host gene expression	The process in which a virus effects a change in gene expression in its host organism. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Some protein processing events may be included when they are required to form an active form of a product from an inactive precursor form.	tmpzr1t_l9r_go_relaxed.owl	regulation by virus of host gene expression							bf	2013-06-20T15:28:26Z					biological_process											owl:Class	
GO:0050246	biolink:NamedThing	questin monooxygenase activity	Catalysis of the reaction: H(+) + NADPH + O(2) + questin = demethylsulochrin + NADP(+).	tmpzr1t_l9r_go_relaxed.owl	questin,NADPH:oxygen oxidoreductase (hydroxylating, anthraquinone-ring-opening)|questin oxygenase activity				RHEA:10836|EC:1.14.13.43|MetaCyc:QUESTIN-MONOOXYGENASE-RXN|KEGG_REACTION:R02417									molecular_function											owl:Class	
GO:2000011	biolink:NamedThing	regulation of adaxial/abaxial pattern formation	Any process that modulates the frequency, rate or extent of adaxial/abaxial pattern formation.	tmpzr1t_l9r_go_relaxed.owl	regulation of adaxial/abaxial pattern specification							tb	2010-08-05T11:20:22Z					biological_process											owl:Class	
GO:0102307	biolink:NamedThing	erythromycin C 3''-o-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine  + erythromycin C <=> S-adenosyl-L-homocysteine  + erythromycin A + H+.	tmpzr1t_l9r_go_relaxed.owl					EC:2.1.1.254|MetaCyc:RXN-12923|RHEA:32647									molecular_function											owl:Class	
GO:1902201	biolink:NamedThing	negative regulation of bacterial-type flagellum-dependent cell motility	Any process that stops, prevents or reduces the frequency, rate or extent of bacterial-type flagellum-dependent cell motility.	tmpzr1t_l9r_go_relaxed.owl	inhibition of bacterial-type flagellar cell motility|down regulation of flagellin-based flagellar cell motility|down regulation of bacterial-type flagellar cell motility|down-regulation of bacterial-type flagellar cell motility|inhibition of flagellin-based flagellar cell motility|downregulation of flagellin-based flagellar cell motility|negative regulation of bacterial-type flagellar cell motility|down-regulation of flagellin-based flagellar cell motility|downregulation of bacterial-type flagellar cell motility|negative regulation of flagellin-based flagellar cell motility							jl	2013-06-06T14:58:41Z					biological_process											owl:Class	
GO:2000394	biolink:NamedThing	positive regulation of lamellipodium morphogenesis	Any process that activates or increases the frequency, rate or extent of lamellipodium morphogenesis.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of lamellipodium organization							mah	2011-02-22T11:19:45Z					biological_process											owl:Class	
GO:1902745	biolink:NamedThing	positive regulation of lamellipodium organization	Any process that activates or increases the frequency, rate or extent of lamellipodium organization.	tmpzr1t_l9r_go_relaxed.owl	up regulation of lamellipodium organization|up-regulation of lamellipodium organization|activation of lamellipodium organization|upregulation of lamellipodium organization							als	2014-02-28T16:27:49Z					biological_process											owl:Class	
GO:1905646	biolink:NamedThing	positive regulation of FACT complex assembly	Any process that activates or increases the frequency, rate or extent of FACT complex assembly.	tmpzr1t_l9r_go_relaxed.owl	upregulation of FACT complex assembly|activation of FACT complex formation|up regulation of FACT complex formation|positive regulation of FACT complex formation|up regulation of Facilitates chromatin transcription complex formation|up-regulation of FACT complex assembly|upregulation of FACT complex formation|activation of FACT complex assembly|up regulation of FACT complex assembly|positive regulation of Facilitates chromatin transcription complex assembly|upregulation of Facilitates chromatin transcription complex assembly|up-regulation of Facilitates chromatin transcription complex assembly|activation of Facilitates chromatin transcription complex formation|up regulation of Facilitates chromatin transcription complex assembly|up-regulation of FACT complex formation|upregulation of Facilitates chromatin transcription complex formation|up-regulation of Facilitates chromatin transcription complex formation|activation of Facilitates chromatin transcription complex assembly|positive regulation of Facilitates chromatin transcription complex formation							pga	2016-11-07T09:14:21Z					biological_process											owl:Class	
GO:0033632	biolink:NamedThing	regulation of cell-cell adhesion mediated by integrin	Any process that modulates the frequency, rate, or extent of cell-cell adhesion mediated by integrin.	tmpzr1t_l9r_go_relaxed.owl	regulation of cell-cell adhesion mediated by integrin complex													biological_process											owl:Class	
GO:0022407	biolink:NamedThing	regulation of cell-cell adhesion	Any process that modulates the frequency, rate or extent of attachment of a cell to another cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0001092	biolink:NamedThing	TFIIA-class transcription factor complex binding	Binding to a general RNA polymerase II transcription factor belonging to the TFIIA complex, one of the complexes involved in formation of the preinitiation complex (PIC) by RNA polymerase II and defined as a basal or general transcription factor.	tmpzr1t_l9r_go_relaxed.owl	TFIIA-class transcription factor binding							krc	2010-10-28T02:37:19Z					molecular_function											owl:Class	
GO:0034157	biolink:NamedThing	positive regulation of toll-like receptor 7 signaling pathway	Any process that activates or increases the frequency, rate, or extent of toll-like receptor 7 signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of toll-like receptor 7 signalling pathway|positive regulation of TLR7 signaling pathway													biological_process											owl:Class	
GO:0070735	biolink:NamedThing	protein-glycine ligase activity	Catalysis of the posttranslational transfer of one or more glycine residues to a specific glutamate residue on a target protein.	tmpzr1t_l9r_go_relaxed.owl	protein glycylase activity				Reactome:R-HSA-8867370			mah	2009-06-19T01:51:21Z					molecular_function											owl:Class	
GO:0140321	biolink:NamedThing	negative regulation by symbiont of host autophagy	Any process in which a symbiont organism decreases the frequency, rate or extent of autophagy in the host cell. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl								pg	2019-04-03T09:21:48Z					biological_process											owl:Class	
GO:0075071	biolink:NamedThing	modulation by symbiont of host autophagy	Any process in which a symbiont organism modulates the frequency, rate or extent of autophagy in the host cell. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	modulation by symbiont of host autophagic process|autophagy involved in symbiotic interaction|autophagy during symbiotic interaction													biological_process											owl:Class	
GO:0019272	biolink:NamedThing	L-alanine biosynthetic process from pyruvate	The chemical reactions and pathways resulting in the formation of alanine from other compounds, including pyruvate.	tmpzr1t_l9r_go_relaxed.owl	L-alanine formation from pyruvate|L-alanine anabolism from pyruvate|L-alanine synthesis from pyruvate				MetaCyc:ALANINE-VALINESYN-PWY|MetaCyc:ALANINE-SYN2-PWY									biological_process											owl:Class	
GO:0009339	biolink:NamedThing	glycolate oxidase complex	An enzyme complex that catalyzes the oxidation of 2-hydroxy acid to form 2-oxo acid and hydrogen peroxide (H2O2). The enzyme is a flavoprotein (FMN).	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0010214	biolink:NamedThing	seed coat development	The process whose specific outcome is the progression of the seed coat over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0061272	biolink:NamedThing	mesonephric connecting tubule development	The process whose specific outcome is the progression of the mesonephric connecting tubule over time, from its formation to the mature structure. The mesonephric connecting tubule is a tubular segment of the mesonephric nephron; it connects the distal tubule to the collecting duct in the mesonephros.	tmpzr1t_l9r_go_relaxed.owl	mesonephric connecting duct development|mesonephric collecting tubule development							dph	2010-09-02T12:00:56Z					biological_process											owl:Class	
GO:0061242	biolink:NamedThing	mesonephric nephron tubule development	The progression of a mesonephric nephron tubule over time, from its initial formation to the mature structure. A mesonephric nephron tubule is an epithelial tube that is part of the mesonephric nephron, the functional part of the mesonephros.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-08-19T03:17:00Z					biological_process											owl:Class	
GO:1990178	biolink:NamedThing	HU-DNA complex	A protein-DNA complex that consists of HU heterodimers (an alpha and a beta chain) assembled into octamers along DNA. HU binds to double-stranded DNA in a structure- and sequence-specific manner and bends the DNA into a nucleosome-like structure.	tmpzr1t_l9r_go_relaxed.owl	HU complex							bhm	2013-08-30T13:06:53Z					cellular_component											owl:Class	
GO:0102461	biolink:NamedThing	kaempferol 3-sophoroside 7-O-rhamnosyltransferase activity	Catalysis of the reaction: kaempferol 3-O-beta-D-glucosyl-(1->2)-beta-D-glucoside + UDP-L-rhamnose <=> kaempferol 3-O-rhamnosyl(1->2)glucoside-7-O-rhamnoside + UDP.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-14009									molecular_function											owl:Class	
GO:0120163	biolink:NamedThing	negative regulation of cold-induced thermogenesis	Any process that stops, prevents, or reduces the rate of cold-induced thermogenesis.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of CIT							krc	2018-05-14T17:18:59Z					biological_process											owl:Class	
GO:0003093	biolink:NamedThing	regulation of glomerular filtration	Any process that modulates the frequency, rate or extent of glomerular filtration. Glomerular filtration is the process in which blood is filtered by the glomerulus into the renal tubule.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0060980	biolink:NamedThing	cell migration involved in coronary vasculogenesis	The orderly movement of a cell from one site to another that will contribute to the differentiation of an endothelial cell that will form the blood vessels of the heart.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-10-06T02:33:06Z					biological_process											owl:Class	
GO:0035441	biolink:NamedThing	cell migration involved in vasculogenesis	The orderly movement of a cell from one site to another that will contribute to the differentiation of an endothelial cell that will form de novo blood vessels and tubes.	tmpzr1t_l9r_go_relaxed.owl								bf	2010-04-09T03:53:01Z					biological_process											owl:Class	
GO:0097176	biolink:NamedThing	epoxide metabolic process	The chemical reactions and pathways involving epoxides, compounds in which an oxygen atom is directly attached to two adjacent or non-adjacent carbon atoms of a carbon chain or ring system; thus cyclic ethers.	tmpzr1t_l9r_go_relaxed.owl	epoxide metabolism							pr	2011-10-10T11:29:49Z					biological_process											owl:Class	
GO:0018410	biolink:NamedThing	C-terminal protein amino acid modification	The alteration of the C-terminal amino acid residue in a protein.	tmpzr1t_l9r_go_relaxed.owl	peptide/protein carboxyl-terminal blocking|peptide or protein carboxyl-terminal blocking													biological_process											owl:Class	
GO:0003306	biolink:NamedThing	Wnt signaling pathway involved in heart development	The series of molecular signals initiated by binding of Wnt protein to a receptor on the surface of the target cell, resulting a change in cell state that contributes to the progression of the heart over time.	tmpzr1t_l9r_go_relaxed.owl	Wnt-activated signaling pathway involved in heart development|Wnt receptor signalling pathway involved in heart development|Wnt receptor signaling pathway involved in heart development							dph	2009-10-22T12:26:07Z					biological_process											owl:Class	
GO:0061311	biolink:NamedThing	cell surface receptor signaling pathway involved in heart development	Any series of molecular signals initiated by the binding of a receptor on the surface of a cell to a physiological ligand, which contributes to the progression of the heart over time.	tmpzr1t_l9r_go_relaxed.owl	cell surface receptor linked signaling pathway involved in heart development|cell surface receptor linked signalling pathway involved in heart development							dph	2010-09-23T09:18:32Z					biological_process											owl:Class	
GO:0006914	biolink:NamedThing	autophagy	The cellular catabolic process in which cells digest parts of their own cytoplasm; allows for both recycling of macromolecular constituents under conditions of cellular stress and remodeling the intracellular structure for cell differentiation.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Autophagy_(cellular)							GO:0016238		biological_process											owl:Class	
GO:1901369	biolink:NamedThing	cyclic 2,3-bisphospho-D-glycerate biosynthetic process	The chemical reactions and pathways resulting in the formation of cyclic 2,3-bisphospho-D-glyceric acid.	tmpzr1t_l9r_go_relaxed.owl	cyclic 2,3-bisphospho-D-glyceric acid synthesis|cyclic 2,3-bisphospho-D-glyceric acid biosynthesis|cyclic 2,3-bisphospho-D-glyceric acid anabolism|cDPG biosynthesis|cyclic 2,3-bisphospho-D-glyceric acid biosynthetic process|cyclic 2,3-bisphospho-D-glyceric acid formation|cyclic 2,3-diphosphoglycerate biosynthesis							bf	2012-09-19T14:17:57Z					biological_process											owl:Class	
GO:0022406	biolink:NamedThing	membrane docking	The initial attachment of a membrane or protein to a target membrane. Docking requires only that the proteins come close enough to interact and adhere.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:2001249	biolink:NamedThing	negative regulation of ammonia assimilation cycle	Any process that stops, prevents or reduces the frequency, rate or extent of ammonia assimilation cycle.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of glutamate metabolism via glutamine and ammonia|negative regulation of glutamate metabolic process via glutamine and ammonia							rl	2011-12-01T10:08:29Z					biological_process											owl:Class	
GO:0045847	biolink:NamedThing	negative regulation of nitrogen utilization	Any process that stops, prevents, or reduces the frequency, rate or extent of nitrogen utilization.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of nitrogen utilization|downregulation of nitrogen utilization|down regulation of nitrogen utilization|inhibition of nitrogen utilization													biological_process											owl:Class	
GO:0055020	biolink:NamedThing	positive regulation of cardiac muscle fiber development	Any process that activates, maintains or increases the frequency, rate or extent of cardiac muscle fiber development.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of cardiac muscle fibre development|upregulation of cardiac muscle fiber development|up regulation of cardiac muscle fiber development|positive regulation of heart muscle fiber development|activation of cardiac muscle fiber development|up-regulation of cardiac muscle fiber development|stimulation of cardiac muscle fiber development													biological_process											owl:Class	
GO:2000727	biolink:NamedThing	positive regulation of cardiac muscle cell differentiation	Any process that activates or increases the frequency, rate or extent of cardiac muscle cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of heart muscle cell differentiation|positive regulation of cardiomyocyte differentiation							vk	2011-06-08T10:51:15Z					biological_process											owl:Class	
GO:1905326	biolink:NamedThing	positive regulation of meiosis I spindle assembly checkpoint	Any process that activates or increases the frequency, rate or extent of the meiosis I spindle assembly checkpoint.	tmpzr1t_l9r_go_relaxed.owl	up regulation of meiosis I spindle assembly checkpoint|activation of meiosis I spindle assembly checkpoint|upregulation of meiosis I spindle assembly checkpoint|up-regulation of meiosis I spindle assembly checkpoint							mah	2016-07-20T12:48:47Z					biological_process											owl:Class	
GO:0044753	biolink:NamedThing	amphisome	Intermediate organelles formed during macroautophagy through the fusion between autophagosomes and endosomes.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-11-27T15:35:25Z					cellular_component											owl:Class	
GO:0005776	biolink:NamedThing	autophagosome	A double-membrane-bounded compartment that engulfs endogenous cellular material as well as invading microorganisms to target them to the lytic vacuole/lysosome for degradation as part of macroautophagy.	tmpzr1t_l9r_go_relaxed.owl	autophagic vacuole|initial autophagic vacuole				NIF_Subcellular:sao8663416959									cellular_component											owl:Class	
GO:1901518	biolink:NamedThing	aspyridone A biosynthetic process	The chemical reactions and pathways resulting in the formation of aspyridone A.	tmpzr1t_l9r_go_relaxed.owl	aspyridone A anabolism|aspyridone A synthesis|aspyridone A formation|aspyridone A biosynthesis							di	2012-10-18T18:31:36Z					biological_process											owl:Class	
GO:1901516	biolink:NamedThing	aspyridone A metabolic process	The chemical reactions and pathways involving aspyridone A.	tmpzr1t_l9r_go_relaxed.owl	aspyridone A metabolism							di	2012-10-18T18:31:28Z					biological_process											owl:Class	
GO:0018156	biolink:NamedThing	peptide cross-linking via (2S,3S,6R)-3-methyl-lanthionine	The formation of a protein-protein cross-link between peptidyl-threonine and peptidyl-cysteine by the synthesis of (2S,3S,6R)-3-methyl-lanthionine (3-methyl-L-lanthionine).	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0112									biological_process											owl:Class	
GO:0045736	biolink:NamedThing	negative regulation of cyclin-dependent protein serine/threonine kinase activity	Any process that stops, prevents, or reduces the frequency, rate or extent of cyclin-dependent protein serine/threonine kinase activity.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0000079	biolink:NamedThing	regulation of cyclin-dependent protein serine/threonine kinase activity	Any process that modulates the frequency, rate or extent of cyclin-dependent protein serine/threonine kinase activity.	tmpzr1t_l9r_go_relaxed.owl	regulation of cyclin-dependent protein kinase activity|regulation of CDK activity													biological_process											owl:Class	
GO:0070153	biolink:NamedThing	mitochondrial leucyl-tRNA aminoacylation	The process of coupling leucine to leucyl-tRNA in a mitochondrion, catalyzed by leucyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1905587	biolink:NamedThing	positive regulation of outer hair cell apoptotic process	Any process that activates or increases the frequency, rate or extent of outer hair cell apoptotic process.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of outer hair cell apoptosis|positive regulation of outer hair cell apoptosis|up-regulation of outer hair cell apoptotic process|up-regulation of cochlear outer hair cell apoptosis|upregulation of cochlear outer hair cell apoptosis|positive regulation of cochlear outer hair cell apoptosis|up-regulation of cochlear outer hair cell apoptotic process|activation of cochlear outer hair cell apoptosis|upregulation of outer hair cell apoptosis|upregulation of outer hair cell apoptotic process|up regulation of cochlear outer hair cell apoptosis|up regulation of outer hair cell apoptotic process|up regulation of cochlear outer hair cell apoptotic process|positive regulation of cochlear outer hair cell apoptotic process|activation of cochlear outer hair cell apoptotic process|up regulation of outer hair cell apoptosis|activation of outer hair cell apoptosis|upregulation of cochlear outer hair cell apoptotic process|activation of outer hair cell apoptotic process							sl	2016-10-24T22:35:51Z					biological_process											owl:Class	
GO:0031540	biolink:NamedThing	regulation of anthocyanin biosynthetic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of anthocyanins.	tmpzr1t_l9r_go_relaxed.owl	regulation of anthocyanin anabolism|regulation of anthocyanin formation|regulation of anthocyanin synthesis|regulation of anthocyanin biosynthesis													biological_process											owl:Class	
GO:0009962	biolink:NamedThing	regulation of flavonoid biosynthetic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of flavonoids.	tmpzr1t_l9r_go_relaxed.owl	regulation of flavonoid anabolism|regulation of flavonoid biosynthesis|regulation of flavonoid formation|regulation of flavonoid synthesis													biological_process											owl:Class	
GO:0050765	biolink:NamedThing	negative regulation of phagocytosis	Any process that stops, prevents, or reduces the frequency, rate or extent of phagocytosis.	tmpzr1t_l9r_go_relaxed.owl	downregulation of phagocytosis|down regulation of phagocytosis|inhibition of phagocytosis|down-regulation of phagocytosis													biological_process											owl:Class	
GO:0003279	biolink:NamedThing	cardiac septum development	The progression of a cardiac septum over time, from its initial formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl	heart septum development							dph	2009-10-20T09:45:13Z					biological_process											owl:Class	
GO:0008673	biolink:NamedThing	2-dehydro-3-deoxygluconokinase activity	Catalysis of the reaction: 2-dehydro-3-deoxy-D-gluconate + ATP = 2-dehydro-3-deoxy-6-phospho-D-gluconate + ADP + 2 H(+).	tmpzr1t_l9r_go_relaxed.owl	2-keto-3-deoxygluconokinase (phosphorylating)|3-deoxy-2-oxo-D-gluconate kinase activity|ketodeoxygluconokinase activity|2-keto-3-deoxy-D-gluconic acid kinase activity|2-keto-3-deoxygluconokinase activity|2-keto-3-deoxygluconate kinase activity|KDG kinase activity|ATP:2-dehydro-3-deoxy-D-gluconate 6-phosphotransferase activity				KEGG_REACTION:R01541|EC:2.7.1.45|RHEA:14797|MetaCyc:DEOXYGLUCONOKIN-RXN									molecular_function											owl:Class	
GO:0061156	biolink:NamedThing	pulmonary artery morphogenesis	The process in which the anatomical structures of the pulmonary artery are generated and organized. The pulmonary artery is the artery that carries blood from the heart to the lungs.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-06-15T09:13:47Z					biological_process											owl:Class	
GO:1901327	biolink:NamedThing	response to tacrolimus	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tacrolimus stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to FK506|response to tacrolimus hydrate							mah	2012-08-30T10:14:40Z					biological_process											owl:Class	
GO:2000523	biolink:NamedThing	regulation of T cell costimulation	Any process that modulates the frequency, rate or extent of T cell costimulation.	tmpzr1t_l9r_go_relaxed.owl	regulation of T-lymphocyte costimulation|regulation of T-cell co-stimulation|regulation of T lymphocyte costimulation|regulation of T cell co-stimulation|regulation of T-cell costimulation							ebc	2011-03-23T10:23:24Z					biological_process											owl:Class	
GO:1903037	biolink:NamedThing	regulation of leukocyte cell-cell adhesion	Any process that modulates the frequency, rate or extent of leukocyte cell-cell adhesion.	tmpzr1t_l9r_go_relaxed.owl	regulation of leukocyte adhesion|regulation of leukocyte cell adhesion					Exogenous expression of ASS1 or NOS3 in HUVECs enhances NO production and inhibits monocyte adhesion		rl	2014-05-19T15:29:58Z					biological_process											owl:Class	
GO:0070930	biolink:NamedThing	trans-translation-dependent protein tagging	A protein modification process in which a polypeptide is added to a nascent polypeptide cotranslationally by trans-translation.	tmpzr1t_l9r_go_relaxed.owl	protein modification by trans-translation|co-translational protein tagging|cotranslational protein tagging					Note that this term is not a child of 'co-translational protein modification process ; GO:0043686' because co-translational protein modification implies modification of a previously incorporated amino acid in a nascent chain, rather than addition of new sequence to the C-terminus.		mah	2009-09-16T04:10:49Z					biological_process											owl:Class	
GO:1905358	biolink:NamedThing	positive regulation of snRNA pseudouridine synthesis	Any process that activates or increases the frequency, rate or extent of snRNA pseudouridine synthesis.	tmpzr1t_l9r_go_relaxed.owl	upregulation of snRNA pseudouridine synthesis|up regulation of snRNA pseudouridine synthesis|activation of snRNA pseudouridine synthesis|up-regulation of snRNA pseudouridine synthesis							se	2016-08-09T19:12:42Z					biological_process											owl:Class	
GO:0150054	biolink:NamedThing	regulation of postsynaptic neurotransmitter receptor diffusion trapping	Any process that modulates the frequency, rate or extent of postsynaptic neurotransmitter receptor diffusion trapping.	tmpzr1t_l9r_go_relaxed.owl								bc	2018-05-10T14:26:59Z					biological_process											owl:Class	
GO:0042191	biolink:NamedThing	methylmercury metabolic process	The chemical reactions and pathways involving methylmercury (MeHg+), a highly toxic organometal which can accumulate in tissues, particularly in fish species.	tmpzr1t_l9r_go_relaxed.owl	methylmercury metabolism													biological_process											owl:Class	
GO:0018941	biolink:NamedThing	organomercury metabolic process	The chemical reactions and pathways involving organomercury compound, any organic compound containing a mercury atom.	tmpzr1t_l9r_go_relaxed.owl	organomercury metabolism				UM-BBD_pathwayID:ogm									biological_process											owl:Class	
GO:0043467	biolink:NamedThing	regulation of generation of precursor metabolites and energy	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of precursor metabolites, substances from which energy is derived, and the processes involved in the liberation of energy from these substances.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0055105	biolink:NamedThing	ubiquitin-protein transferase inhibitor activity	Binds to and stops, prevents or reduces the activity of a ubiquitin-protein transferase.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0004857	biolink:NamedThing	enzyme inhibitor activity	Binds to and stops, prevents or reduces the activity of an enzyme.	tmpzr1t_l9r_go_relaxed.owl	metalloenzyme inhibitor activity					This term should only be used in cases when the regulator directly interacts with the enzyme.						GO:0048551		molecular_function											owl:Class	
GO:0071066	biolink:NamedThing	detection of mechanical stimulus involved in sensory perception of wind	The series of events involved in the perception of wind in which a mechanical stimulus is received and converted into a molecular signal.	tmpzr1t_l9r_go_relaxed.owl	sensory detection of mechanical stimulus during perception of wind|detection of wind|perception of wind, detection of mechanical stimulus|detection of mechanical stimulus involved in sensory perception of air flow|perception of wind, sensory transduction of mechanical stimulus|sensory transduction of mechanical stimulus during perception of wind|sensory transduction of wind|perception of wind, sensory detection of mechanical stimulus							mah	2009-11-04T02:47:36Z					biological_process											owl:Class	
GO:2000818	biolink:NamedThing	negative regulation of myoblast proliferation	Any process that stops, prevents or reduces the frequency, rate or extent of myoblast proliferation.	tmpzr1t_l9r_go_relaxed.owl								pr	2011-07-12T03:06:04Z					biological_process											owl:Class	
GO:0035284	biolink:NamedThing	brain segmentation	Division of the brain into a series of semi-repetitive parts or segments.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0035282	biolink:NamedThing	segmentation	The regionalization process that divides an organism or part of an organism into a series of semi-repetitive parts, or segments, often arranged along a longitudinal axis.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Segmentation_(biology)									biological_process											owl:Class	
GO:0043856	biolink:NamedThing	anti-sigma factor antagonist activity	The function of binding to an anti-sigma factor and stopping, preventing or reducing the rate of its activity.	tmpzr1t_l9r_go_relaxed.owl	anti-anti-sigma factor activity													molecular_function											owl:Class	
GO:0002796	biolink:NamedThing	positive regulation of antimicrobial peptide secretion	Any process that activates or increases the frequency, rate, or extent of antimicrobial peptide secretion.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of antimicrobial peptide secretion|up regulation of antimicrobial peptide secretion|upregulation of antimicrobial peptide secretion|activation of antimicrobial peptide secretion|stimulation of antimicrobial peptide secretion													biological_process											owl:Class	
GO:0002793	biolink:NamedThing	positive regulation of peptide secretion	Any process that activates or increases the frequency, rate, or extent of peptide secretion.	tmpzr1t_l9r_go_relaxed.owl	stimulation of peptide secretion|up regulation of peptide secretion|activation of peptide secretion|up-regulation of peptide secretion|upregulation of peptide secretion													biological_process											owl:Class	
GO:0080193	biolink:NamedThing	diffuse secondary thickening	Lateral growth of the older parts of a stem that occurs when the central parenchyma cells and the not yet fully differentiated fiber cells of the bundle sheaths continue to undergo cell division and expansion for a long period of time, leading to an increase in girth of the stem.	tmpzr1t_l9r_go_relaxed.owl						Occurs in the stems (PO:0009047) of some Arecaceae (palms).		dhl	2012-12-06T15:57:50Z					biological_process											owl:Class	
GO:0046453	biolink:NamedThing	dipyrrin metabolic process	The chemical reactions and pathways involving dipyrrins (pyrromethanes), compounds containing two pyrrole rings linked through a methine, -CH=, group.	tmpzr1t_l9r_go_relaxed.owl	dipyrrin metabolism													biological_process											owl:Class	
GO:0097394	biolink:NamedThing	telomeric repeat-containing RNA transcription by RNA polymerase II	The synthesis of telomeric repeat-containing RNA from a DNA template by RNA polymerase II (Pol II), originating at a Pol II promoter.	tmpzr1t_l9r_go_relaxed.owl	telomeric RNA transcription from Pol II promoter|TERRA RNA transcription from RNA pol II promoter|telomeric repeat-containing RNA transcription from RNA pol II promoter	https://github.com/geneontology/go-ontology/issues/14854						pr	2012-10-23T10:09:15Z					biological_process											owl:Class	
GO:0086049	biolink:NamedThing	membrane repolarization during AV node cell action potential	The process in which ions are transported across a membrane such that the AV node cardiac muscle cell membrane potential changes in the direction from the positive membrane potential at the peak of the action potential towards the negative resting potential.	tmpzr1t_l9r_go_relaxed.owl	membrane repolarization involved in regulation of AV node cardiac muscle cell action potential|membrane repolarization involved in regulation of atrioventricular node cardiac muscle cell action potential							dph	2011-11-16T11:43:38Z					biological_process											owl:Class	
GO:0086009	biolink:NamedThing	membrane repolarization	The process in which ions are transported across a membrane such that the membrane potential changes in the repolarizing direction, toward the steady state potential. For example, the repolarization during an action potential is from a positive membrane potential towards a negative resting potential.	tmpzr1t_l9r_go_relaxed.owl								tb	2011-11-10T08:13:18Z					biological_process											owl:Class	
GO:0045905	biolink:NamedThing	positive regulation of translational termination	Any process that activates or increases the frequency, rate or extent of translational termination.	tmpzr1t_l9r_go_relaxed.owl	upregulation of translational termination|up regulation of translational termination|up-regulation of translational termination|activation of translational termination|stimulation of translational termination													biological_process											owl:Class	
GO:0043243	biolink:NamedThing	positive regulation of protein-containing complex disassembly	Any process that activates or increases the frequency, rate or extent of protein complex disassembly, the disaggregation of a protein complex into its constituent components.	tmpzr1t_l9r_go_relaxed.owl	activation of protein complex disassembly|upregulation of protein complex disassembly|stimulation of protein complex disassembly|up-regulation of protein complex disassembly|up regulation of protein complex disassembly|positive regulation of protein complex disassembly													biological_process											owl:Class	
GO:0032339	biolink:NamedThing	negative regulation of inhibin secretion	Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of inhibin from a cell.	tmpzr1t_l9r_go_relaxed.owl	inhibition of inhibin secretion|down regulation of inhibin secretion|downregulation of inhibin secretion|down-regulation of inhibin secretion													biological_process											owl:Class	
GO:0032338	biolink:NamedThing	regulation of inhibin secretion	Any process that modulates the frequency, rate or extent of the regulated release of inhibin from a cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0031546	biolink:NamedThing	brain-derived neurotrophic factor receptor binding	Binding to a brain-derived neurotrophic factor receptor.	tmpzr1t_l9r_go_relaxed.owl	BDNF receptor binding|brain-derived neurotrophic factor ligand													molecular_function											owl:Class	
GO:0005165	biolink:NamedThing	neurotrophin receptor binding	Binding to a neurotrophin receptor.	tmpzr1t_l9r_go_relaxed.owl	neurotrophin receptor ligand|neurotrophin													molecular_function											owl:Class	
GO:0001924	biolink:NamedThing	regulation of B-1 B cell differentiation	Any process that modulates the frequency, rate, or extent of B-1 B cell differentiation. B-1 B cells are a distinct subset of B cells characterized as being CD5 positive, found predominantly in the peritoneum, pleural cavities, and spleen, and enriched for self-reactivity.	tmpzr1t_l9r_go_relaxed.owl	regulation of B-1 B-lymphocyte differentiation|regulation of B-1 B-cell differentiation|regulation of B-1 B cell development|regulation of B-1 B lymphocyte differentiation					Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.								biological_process											owl:Class	
GO:0045577	biolink:NamedThing	regulation of B cell differentiation	Any process that modulates the frequency, rate or extent of B cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	regulation of B-lymphocyte differentiation|regulation of B-cell differentiation|regulation of B lymphocyte differentiation|regulation of B cell development					Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.								biological_process											owl:Class	
GO:0030757	biolink:NamedThing	3-methylquercitin 7-O-methyltransferase activity	Catalysis of the reaction: 3',4',5,7-tetrahydroxy-3-methoxyflavone + S-adenosyl-L-methionine(1+) = 3',4',5-trihydroxy-3,7-dimethoxyflavone + S-adenosyl-L-homocysteine.	tmpzr1t_l9r_go_relaxed.owl	S-adenosyl-L-methionine:5,7,3',4'-tetrahydroxy-3-methoxyflavone 7-O-methyltransferase activity|flavonol 7-O-methyltransferase activity|7-OMT activity|flavonol 7-methyltransferase activity|S-adenosyl-L-methionine:3',4',5,7-tetrahydroxy-3-methoxyflavone 7-O-methyltransferase activity|3-methylquercetin 7-O-methyltransferase activity				EC:2.1.1.82|KEGG_REACTION:R05323|MetaCyc:2.1.1.82-RXN|RHEA:16181									molecular_function											owl:Class	
GO:0019567	biolink:NamedThing	arabinose biosynthetic process	The chemical reactions and pathways resulting in the formation of arabinose, arabino-pentose.	tmpzr1t_l9r_go_relaxed.owl	arabinose biosynthesis|arabinose anabolism|arabinose formation|arabinose synthesis													biological_process											owl:Class	
GO:0019322	biolink:NamedThing	pentose biosynthetic process	The chemical reactions and pathways resulting in the formation of a pentose, any monosaccharide with a chain of five carbon atoms in the molecule.	tmpzr1t_l9r_go_relaxed.owl	pentose biosynthesis|pentose formation|pentose synthesis|pentose anabolism													biological_process											owl:Class	
GO:1901129	biolink:NamedThing	gentamycin catabolic process	The chemical reactions and pathways resulting in the breakdown of gentamycin.	tmpzr1t_l9r_go_relaxed.owl	gentamycin breakdown|gentamycin catabolism|gentamycin degradation							yaf	2012-07-11T03:26:51Z					biological_process											owl:Class	
GO:1901128	biolink:NamedThing	gentamycin metabolic process	The chemical reactions and pathways involving gentamycin.	tmpzr1t_l9r_go_relaxed.owl	gentamycin metabolism							yaf	2012-07-11T03:26:25Z					biological_process											owl:Class	
GO:1903232	biolink:NamedThing	melanosome assembly	The aggregation, arrangement and bonding together of a set of components to form a melanosome, a tissue-specific, membrane-bounded cytoplasmic organelle within which melanin pigments are synthesized and stored.	tmpzr1t_l9r_go_relaxed.owl	melanosome formation							bf	2014-07-31T10:41:38Z					biological_process											owl:Class	
GO:0048680	biolink:NamedThing	positive regulation of axon regeneration	Any process that activates, maintains or increases the rate of axon regeneration.	tmpzr1t_l9r_go_relaxed.owl	activation of axon regeneration|up regulation of axon regeneration|up-regulation of axon regeneration|upregulation of axon regeneration|stimulation of axon regeneration													biological_process											owl:Class	
GO:0071103	biolink:NamedThing	DNA conformation change	A cellular process that results in a change in the spatial configuration of a DNA molecule. A conformation change can bend DNA, or alter the, twist, writhe, or linking number of a DNA molecule.	tmpzr1t_l9r_go_relaxed.owl	DNA conformation modification							mah	2009-11-09T11:36:34Z					biological_process											owl:Class	
GO:1902660	biolink:NamedThing	negative regulation of glucose mediated signaling pathway	Any process that stops, prevents or reduces the frequency, rate or extent of glucose mediated signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	inhibition of glucose mediated signaling pathway|negative regulation of glucose mediated signalling|down-regulation of glucose mediated signalling|down-regulation of glucose mediated signaling pathway|downregulation of glucose mediated signalling|inhibition of glucose mediated signalling|down regulation of glucose mediated signalling|down regulation of glucose mediated signaling pathway|downregulation of glucose mediated signaling pathway							di	2014-01-28T17:54:31Z					biological_process											owl:Class	
GO:1902659	biolink:NamedThing	regulation of glucose mediated signaling pathway	Any process that modulates the frequency, rate or extent of glucose mediated signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	regulation of glucose mediated signalling							di	2014-01-28T17:54:21Z					biological_process											owl:Class	
GO:0002088	biolink:NamedThing	lens development in camera-type eye	The process whose specific outcome is the progression of the lens over time, from its formation to the mature structure. The lens is a transparent structure in the eye through which light is focused onto the retina. An example of this process is found in Mus musculus.	tmpzr1t_l9r_go_relaxed.owl	lens development|lens development in camera-style eye													biological_process											owl:Class	
GO:0051179	biolink:NamedThing	localization	Any process in which a cell, a substance, or a cellular entity, such as a protein complex or organelle, is transported, tethered to or otherwise maintained in a specific location. In the case of substances, localization may also be achieved via selective degradation.	tmpzr1t_l9r_go_relaxed.owl	single-organism localization|establishment and maintenance of substance location|establishment and maintenance of localization|establishment and maintenance of cellular component location|establishment and maintenance of position|localisation|single organism localization|establishment and maintenance of substrate location							jl	2013-12-18T13:51:04Z			GO:1902578		biological_process											owl:Class	
GO:0040033	biolink:NamedThing	RNA-mediated gene silencing by inhibition of translation	Any process, mediated by small non-coding RNAs, that stops, prevents or reduces the rate that mRNAs are effectively translated into protein.	tmpzr1t_l9r_go_relaxed.owl	down regulation of mRNA translation, ncRNA-mediated|negative regulation of translation, ncRNA-mediated|inhibition of mRNA translation, ncRNA-mediated|down-regulation of mRNA translation, ncRNA-mediated|downregulation of mRNA translation, ncRNA-mediated													biological_process											owl:Class	
GO:0038195	biolink:NamedThing	urokinase plasminogen activator signaling pathway	A series of molecular signals initiated by the binding of urokinase plasminogen activator to a receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.	tmpzr1t_l9r_go_relaxed.owl	uPA signaling pathway							bf	2013-10-28T09:14:13Z					biological_process											owl:Class	
GO:0040020	biolink:NamedThing	regulation of meiotic nuclear division	Any process that modulates the frequency, rate or extent of meiotic nuclear division, the process in which the nucleus of a diploid cell divides twice forming four haploid cells, one or more of which usually function as gametes.	tmpzr1t_l9r_go_relaxed.owl	regulation of meiosis													biological_process											owl:Class	
GO:0032865	biolink:NamedThing	ERMES complex	A protein complex that links the endoplasmic reticulum with mitochondria and may have a role in promoting exchange of calcium and phospholipids between the two organelles.	tmpzr1t_l9r_go_relaxed.owl	ER-mitochondria encounter structure|Mdm10/Mdm12/Mmm1 complex|MMM1 complex|mitochore													cellular_component											owl:Class	
GO:0140534	biolink:NamedThing	endoplasmic reticulum protein-containing complex	A protein complex that is part of an endoplasmic reticulum.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/19952						pg	2020-10-28T12:14:12Z					cellular_component											owl:Class	
GO:0042881	biolink:NamedThing	D-galactonate transmembrane transporter activity	Enables the transfer of D-galactonate, the D-enantiomer of galactonate, from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0042879	biolink:NamedThing	aldonate transmembrane transporter activity	Enables the transfer of aldonate from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0008851	biolink:NamedThing	ethanolamine ammonia-lyase activity	Catalysis of the reaction: ethanolamine = acetaldehyde + NH3.	tmpzr1t_l9r_go_relaxed.owl	ethanolamine deaminase activity|ethanolamine ammonia-lyase (acetaldehyde-forming) activity				EC:4.3.1.7|RHEA:15313|MetaCyc:ETHAMLY-RXN									molecular_function											owl:Class	
GO:0016841	biolink:NamedThing	ammonia-lyase activity	Catalysis of the release of ammonia by the cleavage of a carbon-nitrogen bond or the reverse reaction with ammonia as a substrate.	tmpzr1t_l9r_go_relaxed.owl					EC:4.3.1.-									molecular_function											owl:Class	
GO:0035921	biolink:NamedThing	desmosome disassembly	The controlled breakdown of a desmosome. A desmosome is a patch-like intercellular junction found in vertebrate tissues, consisting of parallel zones of two cell membranes, separated by an space of 25-35 nm, and having dense fibrillar plaques in the subjacent cytoplasm.	tmpzr1t_l9r_go_relaxed.owl	desmosome dissociation							bf	2011-07-05T01:33:25Z					biological_process											owl:Class	
GO:1901990	biolink:NamedThing	regulation of mitotic cell cycle phase transition	Any process that modulates the frequency, rate or extent of mitotic cell cycle phase transition.	tmpzr1t_l9r_go_relaxed.owl	mitotic cell cycle control							jl	2013-03-19T16:14:38Z					biological_process											owl:Class	
GO:0007346	biolink:NamedThing	regulation of mitotic cell cycle	Any process that modulates the rate or extent of progress through the mitotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl	modulation of mitotic cell cycle progression|regulation of progression through mitotic cell cycle|mitotic cell cycle modulation|mitotic cell cycle regulator|regulation of mitotic cell cycle progression|mitotic cell cycle regulation													biological_process											owl:Class	
GO:0043783	biolink:NamedThing	oxidoreductase activity, acting on metal ions, flavin as acceptor	Catalysis of an oxidation-reduction in which the metal ion is reduced and flavin acts as an electron acceptor.	tmpzr1t_l9r_go_relaxed.owl	oxidoreductase activity, oxidizing metal ions with flavin as acceptor|oxidoreductase activity, reducing metal ions, flavin as acceptor	https://github.com/geneontology/go-ontology/issues/20675|https://github.com/geneontology/go-ontology/issues/20682			EC:1.16.8.-									molecular_function											owl:Class	
GO:0016722	biolink:NamedThing	oxidoreductase activity, acting on metal ions	Catalysis of an oxidation-reduction in which the oxidation state of metal ion is altered.	tmpzr1t_l9r_go_relaxed.owl	oxidoreductase activity, oxidizing metal ions|oxidoreductase activity, reducing metal ions	https://github.com/geneontology/go-ontology/issues/20675			Reactome:R-HSA-917805|EC:1.16.-.-									molecular_function											owl:Class	
GO:0030726	biolink:NamedThing	male germline ring canal formation	Formation of the intercellular bridges that connect the germ-line cells of a male cyst.	tmpzr1t_l9r_go_relaxed.owl	testicular ring canal formation|spermatocyte ring canal formation													biological_process											owl:Class	
GO:0030725	biolink:NamedThing	germline ring canal formation	Assembly of the cytoplasmic bridges between developing spermatogonial or oogonial cysts.	tmpzr1t_l9r_go_relaxed.owl	ring canal formation													biological_process											owl:Class	
GO:0009595	biolink:NamedThing	detection of biotic stimulus	The series of events in which a biotic stimulus, one caused or produced by a living organism, is received and converted into a molecular signal.	tmpzr1t_l9r_go_relaxed.owl	perception of biotic stimulus											GO:0009596		biological_process											owl:Class	
GO:0009607	biolink:NamedThing	response to biotic stimulus	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biotic stimulus, a stimulus caused or produced by a living organism.	tmpzr1t_l9r_go_relaxed.owl	response to biotic stress					Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.								biological_process											owl:Class	
GO:0051309	biolink:NamedThing	female meiosis chromosome separation	The process in which paired chromosomes are physically detached from each other during female meiosis.	tmpzr1t_l9r_go_relaxed.owl	chromosome separation during female meiosis|female meiosis chromosome resolution													biological_process											owl:Class	
GO:0051304	biolink:NamedThing	chromosome separation	The cell cycle process in which paired chromosomes are detached from each other. Chromosome separation begins with the release of cohesin complexes from chromosomes; in budding yeast, this includes the cleavage of cohesin complexes along the chromosome arms, followed by the separation of the centromeric regions. Chromosome separation also includes formation of chromatid axes mediated by condensins, and ends with the disentangling of inter-sister catenation catalyzed by topoisomerase II (topo II).	tmpzr1t_l9r_go_relaxed.owl	chromatid release|rDNA separation											GO:0034500		biological_process											owl:Class	
GO:1902075	biolink:NamedThing	cellular response to salt	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a salt stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to salinity							mls	2013-04-22T15:42:02Z					biological_process											owl:Class	
GO:0106083	biolink:NamedThing	nuclear membrane protein complex	Any protein complex that is part of the nuclear membrane.	tmpzr1t_l9r_go_relaxed.owl								hjd	2018-01-05T19:51:26Z					cellular_component											owl:Class	
GO:1902624	biolink:NamedThing	positive regulation of neutrophil migration	Any process that activates or increases the frequency, rate or extent of neutrophil migration.	tmpzr1t_l9r_go_relaxed.owl	activation of neutrophil migration|up-regulation of neutrophil migration|upregulation of neutrophil migration|up regulation of neutrophil migration							sl	2014-01-15T18:58:58Z					biological_process											owl:Class	
GO:0004520	biolink:NamedThing	endodeoxyribonuclease activity	Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acid by creating internal breaks.	tmpzr1t_l9r_go_relaxed.owl	DNA nicking activity|endonuclease G activity				Reactome:R-HSA-5687464|Reactome:R-HSA-110359|Reactome:R-HSA-6782224|Reactome:R-HSA-6782204|Reactome:R-HSA-5690988|Reactome:R-HSA-5686440|Reactome:R-HSA-5686657|Reactome:R-HSA-5693584|Reactome:R-HSA-5693608|Reactome:R-HSA-9023941									molecular_function											owl:Class	
GO:0004519	biolink:NamedThing	endonuclease activity	Catalysis of the hydrolysis of ester linkages within nucleic acids by creating internal breaks.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-72180|Reactome:R-HSA-5358518|Reactome:R-HSA-5693533|Reactome:R-HSA-5690990|Reactome:R-HSA-5358512									molecular_function											owl:Class	
GO:0006796	biolink:NamedThing	phosphate-containing compound metabolic process	The chemical reactions and pathways involving the phosphate group, the anion or salt of any phosphoric acid.	tmpzr1t_l9r_go_relaxed.owl	phosphate metabolism|phosphate metabolic process													biological_process											owl:Class	
GO:0099628	biolink:NamedThing	neurotransmitter receptor diffusion trapping	The process by which diffusing neurotransmitter receptor becomes trapped in region of the plasma membrane.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0098953	biolink:NamedThing	receptor diffusion trapping	The process by which a membrane receptor, diffusing freely within the plasma membeane, becomes trapped in some plasma membrane region.  This can happen when a receptor bind, directly or indirectly, to some component of the underlying matrix.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0004099	biolink:NamedThing	chitin deacetylase activity	Catalysis of the reaction: chitin + H2O = chitosan + acetate.	tmpzr1t_l9r_go_relaxed.owl	chitin amidohydrolase activity				MetaCyc:CHITIN-DEACETYLASE-RXN|RHEA:10464|EC:3.5.1.41									molecular_function											owl:Class	
GO:0035045	biolink:NamedThing	sperm plasma membrane disassembly	The gradual disintegration of the sperm plasma membrane following insemination. This process is seen in Drosophila after entry of the entire sperm, surrounded by its plasma membrane, into the egg.	tmpzr1t_l9r_go_relaxed.owl	sperm plasma membrane catabolism|sperm plasma membrane degradation|sperm plasma membrane breakdown													biological_process											owl:Class	
GO:0002047	biolink:NamedThing	phenazine biosynthetic process	The chemical reactions and pathways resulting in the formation of a phenazine antibiotic, a polycyclic pyrazine with two nitrogen atoms in the ring.	tmpzr1t_l9r_go_relaxed.owl	acridizine biosynthetic process|azophenylene biosynthesis|acridizine biosynthesis|dibenzo-p-diazine biosynthesis|dibenzo-p-diazine biosynthetic process|dibenzopyrazine biosynthesis|dibenzopyrazine biosynthetic process|azophenylene biosynthetic process													biological_process											owl:Class	
GO:0060958	biolink:NamedThing	endocardial cell development	The progression of an endocardial cell over time, from its formation to the mature cell. An endocardial cell is a specialized endothelial cell that makes up the endocardium portion of the heart.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-09-29T03:26:59Z					biological_process											owl:Class	
GO:0055006	biolink:NamedThing	cardiac cell development	The process whose specific outcome is the progression of a cardiac cell over time, from its formation to the mature state. A cardiac cell is a cell that will form part of the cardiac organ of an individual.	tmpzr1t_l9r_go_relaxed.owl	heart cell development|cardiocyte development													biological_process											owl:Class	
GO:1905315	biolink:NamedThing	cell proliferation involved in endocardial cushion morphogenesis	Any cell proliferation that is involved in endocardial cushion morphogenesis.	tmpzr1t_l9r_go_relaxed.owl								rl	2016-07-12T13:56:36Z					biological_process											owl:Class	
GO:0061323	biolink:NamedThing	cell proliferation involved in heart morphogenesis	The multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to the shaping of the heart.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-09-28T09:05:26Z					biological_process											owl:Class	
GO:0021774	biolink:NamedThing	retinoic acid receptor signaling pathway involved in ventral spinal cord interneuron specification	The series of molecular signals initiated by binding of a ligand to a retinoic acid receptor in a precursor cell in the ventral spinal cord that contributes to the commitment of the precursor cell to an interneuron fate.	tmpzr1t_l9r_go_relaxed.owl	retinoic acid receptor signalling pathway involved in ventral spinal cord interneuron specification													biological_process											owl:Class	
GO:0097479	biolink:NamedThing	synaptic vesicle localization	Any process in which a synaptic vesicle or vesicles are transported to, and/or maintained in, a specific location.	tmpzr1t_l9r_go_relaxed.owl	synaptic vesicle localisation|establishment and maintenance of synaptic vesicle localization|establishment and maintenance of synaptic vesicle position							pr	2013-05-22T14:29:55Z					biological_process											owl:Class	
GO:0043381	biolink:NamedThing	negative regulation of memory T cell differentiation	Any process that stops, prevents, or reduces the rate of memory T cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of memory T-lymphocyte differentiation|down regulation of memory T cell differentiation|inhibition of memory T cell differentiation|negative regulation of memory T lymphocyte differentiation|negative regulation of memory T cell development|downregulation of memory T cell differentiation|down-regulation of memory T cell differentiation|negative regulation of memory T-cell differentiation					Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.								biological_process											owl:Class	
GO:0072750	biolink:NamedThing	cellular response to leptomycin B	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leptomycin B stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2012-09-10T14:07:32Z					biological_process											owl:Class	
GO:0046075	biolink:NamedThing	dTTP metabolic process	The chemical reactions and pathways involving dTTP, deoxyribosylthymine triphosphate.	tmpzr1t_l9r_go_relaxed.owl	dTTP metabolism													biological_process											owl:Class	
GO:0009219	biolink:NamedThing	pyrimidine deoxyribonucleotide metabolic process	The chemical reactions and pathways involving a pyrimidine deoxynucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.	tmpzr1t_l9r_go_relaxed.owl	pyrimidine deoxyribonucleotide metabolism													biological_process											owl:Class	
GO:0032030	biolink:NamedThing	myosin I light chain binding	Binding to a light chain of a myosin I complex.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0021948	biolink:NamedThing	inward migration of deep nuclear neurons	The directed movement of a deep nuclear neuron from the rostrodorsal region of the cerebellar plate to their final more ventral position.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0002629	biolink:NamedThing	negative regulation of proteolysis associated with antigen processing and presentation	Any process that stops, prevents, or reduces the frequency, rate, or extent of proteolysis associated with antigen processing and presentation.	tmpzr1t_l9r_go_relaxed.owl	inhibition of proteolysis associated with antigen processing and presentation|downregulation of proteolysis associated with antigen processing and presentation|down-regulation of proteolysis associated with antigen processing and presentation|down regulation of proteolysis associated with antigen processing and presentation													biological_process											owl:Class	
GO:0002628	biolink:NamedThing	regulation of proteolysis associated with antigen processing and presentation	Any process that modulates the frequency, rate, or extent of proteolysis associated with antigen processing and presentation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0044423	biolink:NamedThing	virion component	Any constituent part of a virion, a complete fully infectious extracellular virus particle.	tmpzr1t_l9r_go_relaxed.owl	virion|complete virus particle|virion part				Wikipedia:Virus							GO:0019012		cellular_component											owl:Class	
GO:0005575	biolink:NamedThing	cellular_component	A location, relative to cellular compartments and structures, occupied by a macromolecular machine when it carries out a molecular function. There are two ways in which the gene ontology describes locations of gene products: (1) relative to cellular structures (e.g., cytoplasmic side of plasma membrane) or compartments (e.g., mitochondrion), and (2) the stable macromolecular complexes of which they are parts (e.g., the ribosome).	tmpzr1t_l9r_go_relaxed.owl	cellular component|cell or subcellular entity|subcellular entity				NIF_Subcellular:sao1337158144	Note that, in addition to forming the root of the cellular component ontology, this term is recommended for use for the annotation of gene products whose cellular component is unknown. When this term is used for annotation, it indicates that no information was available about the cellular component of the gene product annotated as of the date the annotation was made; the evidence code 'no data' (ND), is used to indicate this.						GO:0008372		cellular_component											owl:Class	
GO:0051557	biolink:NamedThing	leucoanthocyanidin biosynthetic process	The chemical reactions and pathways resulting in the formation of leucoanthocyanidins, a class of colorless intermediates in the biosynthetic pathway of the pigmented flavonoids.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0009813	biolink:NamedThing	flavonoid biosynthetic process	The chemical reactions and pathways resulting in the formation of flavonoids, a group of phenolic derivatives containing a flavan skeleton.	tmpzr1t_l9r_go_relaxed.owl	flavonoid formation|flavonoid anabolism|flavonoid biosynthesis|flavonoid synthesis				MetaCyc:PWY1F-FLAVSYN|Wikipedia:Flavonoid									biological_process											owl:Class	
GO:0001933	biolink:NamedThing	negative regulation of protein phosphorylation	Any process that stops, prevents or reduces the rate of addition of phosphate groups to amino acids within a protein.	tmpzr1t_l9r_go_relaxed.owl	down regulation of protein amino acid phosphorylation|inhibition of protein amino acid phosphorylation|negative regulation of protein amino acid phosphorylation|downregulation of protein amino acid phosphorylation|down-regulation of protein amino acid phosphorylation													biological_process											owl:Class	
GO:0033028	biolink:NamedThing	myeloid cell apoptotic process	Any apoptotic process in a myeloid cell, a cell of the monocyte, granulocyte, mast cell, megakaryocyte, or erythroid lineage.	tmpzr1t_l9r_go_relaxed.owl	apoptosis of myeloid cells|myeloid cell apoptosis													biological_process											owl:Class	
GO:0030632	biolink:NamedThing	D-alanine biosynthetic process	The chemical reactions and pathways resulting in the formation of D-alanine, the D-enantiomer of the amino acid alanine, i.e (2R)-2-aminopropanoic acid.	tmpzr1t_l9r_go_relaxed.owl	D-alanine formation|D-alanine synthesis|D-alanine anabolism|D-alanine biosynthesis													biological_process											owl:Class	
GO:0046145	biolink:NamedThing	D-alanine family amino acid biosynthetic process	The chemical reactions and pathways resulting in the formation of D-alanine and related amino acids.	tmpzr1t_l9r_go_relaxed.owl	D-alanine family amino acid anabolism|D-alanine family amino acid biosynthesis|D-alanine family amino acid synthesis|D-alanine family amino acid formation													biological_process											owl:Class	
GO:0035116	biolink:NamedThing	embryonic hindlimb morphogenesis	The process, occurring in the embryo, by which the anatomical structures of the hindlimbs are generated and organized. The hindlimbs are the posterior limbs of an animal.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0035137	biolink:NamedThing	hindlimb morphogenesis	The process in which the anatomical structures of the hindlimb are generated and organized.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0051055	biolink:NamedThing	negative regulation of lipid biosynthetic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of lipids.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of lipid biosynthesis|down regulation of lipid biosynthetic process|negative regulation of lipid anabolism|negative regulation of lipid synthesis|negative regulation of lipid formation|downregulation of lipid biosynthetic process|inhibition of lipid biosynthetic process|down-regulation of lipid biosynthetic process|negative regulation of lipogenesis													biological_process											owl:Class	
GO:0009890	biolink:NamedThing	negative regulation of biosynthetic process	Any process that stops, prevents, or reduces the rate of the chemical reactions and pathways resulting in the formation of substances.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of formation|inhibition of biosynthetic process|downregulation of biosynthetic process|down-regulation of biosynthetic process|down regulation of biosynthetic process|negative regulation of synthesis|negative regulation of biosynthesis|negative regulation of anabolism													biological_process											owl:Class	
GO:0035133	biolink:NamedThing	post-embryonic caudal fin morphogenesis	The process, occurring after embryonic development, by which the anatomical structures of the caudal fin are generated and organized. The caudal fin is an unpaired medial fin mounted at the caudal end of the fish and is the main fin used for propulsion.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0035132	biolink:NamedThing	post-embryonic medial fin morphogenesis	The process, occurring after embryonic development, by which the anatomical structures of the medial fin are generated and organized. Medial fins are unpaired fins of fish, usually located dorsomedially or ventromedially and primarily used for stability while swimming.	tmpzr1t_l9r_go_relaxed.owl	post-embryonic unpaired fin morphogenesis													biological_process											owl:Class	
GO:0061269	biolink:NamedThing	mesonephric glomerular mesangial cell proliferation involved in mesonephros development	The multiplication or reproduction of glomerular mesangial cells in the mesonephros, resulting in the expansion of the population.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-08-30T03:20:57Z					biological_process											owl:Class	
GO:0072110	biolink:NamedThing	glomerular mesangial cell proliferation	The multiplication or reproduction of glomerular mesangial cells, resulting in the expansion of the population.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-02-22T10:45:47Z					biological_process											owl:Class	
GO:0061252	biolink:NamedThing	mesonephric glomerular epithelial cell fate commitment	The process in which the developmental fate of a cell becomes restricted such that it will develop into a mesonephric glomerular epithelial cell. Mesonephric glomerular epithelial cells are specialized epithelial cells that form part of the mesonephric glomerulus; there are two types, mesonephric glomerular parietal epithelial cells and mesonephric glomerular visceral epithelial cells.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-08-30T01:23:50Z					biological_process											owl:Class	
GO:0072314	biolink:NamedThing	glomerular epithelial cell fate commitment	The process in which the developmental fate of a cell becomes restricted such that it will develop into a glomerular epithelial cell. Glomerular epithelial cells are specialized epithelial cells that form part of the glomerulus; there are two types, glomerular parietal epithelial cells and glomerular visceral epithelial cells.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-04-09T07:02:25Z					biological_process											owl:Class	
GO:0043462	biolink:NamedThing	regulation of ATP-dependent activity	Any process that modulates the rate of an ATP-dependent activity.	tmpzr1t_l9r_go_relaxed.owl	regulation of ATPase activity|regulation of adenosinetriphosphatase activity	https://github.com/geneontology/go-ontology/issues/22371												biological_process											owl:Class	
GO:0061890	biolink:NamedThing	positive regulation of astrocyte activation	Any process that increases the frequency, rate or extent of astrocyte activation.	tmpzr1t_l9r_go_relaxed.owl								dph	2017-06-01T22:31:50Z					biological_process											owl:Class	
GO:0048711	biolink:NamedThing	positive regulation of astrocyte differentiation	Any process that activates or increases the frequency, rate or extent of astrocyte differentiation.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of astrocyte differentiation|stimulation of astrocyte differentiation|upregulation of astrocyte differentiation|up regulation of astrocyte differentiation|activation of astrocyte differentiation													biological_process											owl:Class	
GO:1900303	biolink:NamedThing	regulation of laminaritriose transport	Any process that modulates the frequency, rate or extent of laminaritriose transport.	tmpzr1t_l9r_go_relaxed.owl								tt	2012-04-05T07:57:49Z					biological_process											owl:Class	
GO:0001198	biolink:NamedThing	negative regulation of mating-type specific transcription from RNA polymerase II promoter	Any mating-type specific process that stops, prevents or reduces the rate of transcription from an RNA polymerase II promoter.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of RNA polymerase II transcription, mating-type specific|down regulation of RNA polymerase II transcription, mating-type specific|downregulation of RNA polymerase II transcription, mating-type specific|inhibition of RNA polymerase II transcription, mating-type specific							krc	2011-11-23T09:36:06Z					biological_process											owl:Class	
GO:0001196	biolink:NamedThing	regulation of mating-type specific transcription from RNA polymerase II promoter	Any mating-type specific process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter.	tmpzr1t_l9r_go_relaxed.owl								krc	2011-11-23T09:25:32Z					biological_process											owl:Class	
GO:2000656	biolink:NamedThing	regulation of apolipoprotein binding	Any process that modulates the frequency, rate or extent of apolipoprotein binding.	tmpzr1t_l9r_go_relaxed.owl								vk	2011-05-02T05:33:41Z					biological_process											owl:Class	
GO:0046317	biolink:NamedThing	regulation of glucosylceramide biosynthetic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glucosylceramide.	tmpzr1t_l9r_go_relaxed.owl	regulation of glucosylceramide formation|regulation of glucosylceramide synthesis|regulation of glucosylceramide anabolism|regulation of glucosylceramide biosynthesis													biological_process											owl:Class	
GO:0008700	biolink:NamedThing	4-hydroxy-2-oxoglutarate aldolase activity	Catalysis of the reaction: 4-hydroxy-2-oxoglutarate = pyruvate + glyoxylate.	tmpzr1t_l9r_go_relaxed.owl	hydroxyketoglutarate aldolase activity|2-keto-4-hydroxybutyrate aldolase activity|4-hydroxy-2-ketoglutarate aldolase activity|DL-4-hydroxy-2-ketoglutarate aldolase activity|4-hydroxy-2-oxoglutarate glyoxylate-lyase activity|2-oxo-4-hydroxyglutaric aldolase activity|2-keto-4-hydroxyglutaric aldolase activity|KHG-aldolase activity|4-hydroxy-2-ketoglutaric aldolase activity|4-hydroxy-2-oxoglutarate glyoxylate-lyase (pyruvate-forming)|2-oxo-4-hydroxyglutarate aldolase activity|hydroxyketoglutaric aldolase activity|2-keto-4-hydroxyglutarate aldolase activity				EC:4.1.3.16|MetaCyc:4OH2OXOGLUTARALDOL-RXN|RHEA:18169|Reactome:R-HSA-6784423									molecular_function											owl:Class	
GO:0033756	biolink:NamedThing	Oplophorus-luciferin 2-monooxygenase activity	Catalysis of the reaction: Oplophorus luciferin + O2 = oxidized Oplophorus luciferin + CO2 + hnu.	tmpzr1t_l9r_go_relaxed.owl	Oplophorus-luciferin:oxygen 2-oxidoreductase (decarboxylating) activity|Oplophorus luciferase activity				MetaCyc:RXN-3361|EC:1.13.12.13|RHEA:20417									molecular_function											owl:Class	
GO:0098903	biolink:NamedThing	regulation of membrane repolarization during action potential	Any process that modulates the rate, frequency or extent of membrane repolarization during an action potential. Membrane repolarization is the process in which membrane potential changes in the repolarizing direction, towards the resting potential.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0098900	biolink:NamedThing	regulation of action potential	Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination. This typically occurs via modulation of the activity or expression of voltage-gated ion channels.	tmpzr1t_l9r_go_relaxed.owl						The ion channels through which current flows during an action potential should be annotated to the process 'action potential'. Gene products involved in modulating the characteristics of an action potential via changing the expression levels or the activity of these channels (e.g. modulating their kinetics or voltage sensitivity) should be annotated to this regulation term.								biological_process											owl:Class	
GO:1904171	biolink:NamedThing	negative regulation of bleb assembly	Any process that stops, prevents or reduces the frequency, rate or extent of bleb assembly.	tmpzr1t_l9r_go_relaxed.owl	inhibition of bleb assembly|down-regulation of bleb assembly|negative regulation of cell blebbing|inhibition of cell blebbing|down regulation of cell blebbing|downregulation of bleb assembly|down-regulation of cell blebbing|down regulation of bleb assembly|downregulation of cell blebbing							als	2015-04-23T09:32:25Z					biological_process											owl:Class	
GO:0071175	biolink:NamedThing	MAML2-RBP-Jkappa-ICN1 complex	A protein complex that consists of the intracellular domain of Notch1 (ICN1), the DNA-binding transcription factor RBP-Jkappa, and the transcriptional coactivator Mastermind-like-2 (MAML2); the complex is involved in transcriptional activation in response to Notch-mediated signaling.	tmpzr1t_l9r_go_relaxed.owl	MAML2-RBP-Jkappa-Notch1 complex							mah	2009-11-23T02:36:28Z					cellular_component											owl:Class	
GO:0002925	biolink:NamedThing	positive regulation of humoral immune response mediated by circulating immunoglobulin	Any process that activates or increases the frequency, rate, or extent of a humoral immune response mediated by circulating immunoglobulin.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of humoral immune response mediated by circulating immunoglobulin|activation of humoral immune response mediated by circulating immunoglobulin|stimulation of humoral immune response mediated by circulating immunoglobulin|upregulation of humoral immune response mediated by circulating immunoglobulin|up regulation of humoral immune response mediated by circulating immunoglobulin													biological_process											owl:Class	
GO:0002922	biolink:NamedThing	positive regulation of humoral immune response	Any process that activates or increases the frequency, rate, or extent of a humoral immune response.	tmpzr1t_l9r_go_relaxed.owl	stimulation of humoral immune response|up-regulation of humoral immune response|activation of humoral immune response|up regulation of humoral immune response|upregulation of humoral immune response													biological_process											owl:Class	
GO:0070382	biolink:NamedThing	exocytic vesicle	A transport vesicle that mediates transport from an intracellular compartment to the plasma membrane, and fuses with the plasma membrane to release various cargo molecules, such as proteins or hormones, by exocytosis.	tmpzr1t_l9r_go_relaxed.owl	exocytic constitutive secretory pathway transport vesicle|exocytotic vesicle													cellular_component											owl:Class	
GO:0099503	biolink:NamedThing	secretory vesicle	A cytoplasmic, membrane bound vesicle that is capable of fusing to the plasma membrane to release its contents into the extracellular space.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0042848	biolink:NamedThing	sorbose catabolic process	The chemical reactions and pathways resulting in the breakdown of sorbose, the ketohexose xylo-2-hexulose. Sorbose is produced commercially by fermentation and is used as an intermediate in the manufacture of ascorbic acid.	tmpzr1t_l9r_go_relaxed.owl	sorbose degradation|sorbose catabolism|sorbose breakdown													biological_process											owl:Class	
GO:0019320	biolink:NamedThing	hexose catabolic process	The chemical reactions and pathways resulting in the breakdown of hexose, any monosaccharide with a chain of six carbon atoms in the molecule.	tmpzr1t_l9r_go_relaxed.owl	hexose degradation|hexose catabolism|hexose breakdown													biological_process											owl:Class	
GO:0106259	biolink:NamedThing	cell-to-cell migration in host	The directional movement of a symbiont from one host cell to another.	tmpzr1t_l9r_go_relaxed.owl								hjd	2020-05-01T14:09:35Z					biological_process											owl:Class	
GO:0044001	biolink:NamedThing	migration in host	The directional movement of an organism from one place to another within its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	migration within host													biological_process											owl:Class	
GO:0030307	biolink:NamedThing	positive regulation of cell growth	Any process that activates or increases the frequency, rate, extent or direction of cell growth.	tmpzr1t_l9r_go_relaxed.owl	stimulation of cell growth|up regulation of cell growth|upregulation of cell growth|activation of cell growth|up-regulation of cell growth													biological_process											owl:Class	
GO:0048522	biolink:NamedThing	positive regulation of cellular process	Any process that activates or increases the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of cellular physiological process|upregulation of cellular process|activation of cellular process|up-regulation of cellular process|stimulation of cellular process|up regulation of cellular process											GO:0051242		biological_process											owl:Class	
GO:1904328	biolink:NamedThing	regulation of myofibroblast contraction	Any process that modulates the frequency, rate or extent of myofibroblast contraction.	tmpzr1t_l9r_go_relaxed.owl	regulation of MF contraction|regulation of MFB contraction							sl	2015-06-11T15:30:29Z					biological_process											owl:Class	
GO:1902960	biolink:NamedThing	negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of aspartic protease activity involved in amyloid precursor protein catabolism|negative regulation of aspartate protease activity involved in APP catabolism|downregulation of aspartyl protease activity involved in amyloid precursor protein catabolism|inhibition of aspartic-type endopeptidase activity involved in amyloid precursor protein degradation|down regulation of aspartyl protease activity involved in amyloid precursor protein breakdown|down-regulation of aspartyl protease activity involved in amyloid precursor protein degradation|down regulation of carboxyl protease activity involved in amyloid precursor protein degradation|downregulation of aspartic endopeptidase activity involved in APP catabolic process|down regulation of aspartic protease activity involved in amyloid precursor protein degradation|down regulation of aspartyl protease activity involved in amyloid precursor protein degradation|down regulation of aspartic protease activity involved in APP catabolic process|downregulation of aspartate protease activity involved in amyloid precursor protein catabolism|downregulation of aspartic protease activity involved in amyloid precursor protein breakdown|downregulation of carboxyl protease activity involved in amyloid precursor protein catabolism|down-regulation of aspartyl protease activity involved in amyloid precursor protein breakdown|down regulation of aspartate protease activity involved in APP catabolic process|down-regulation of aspartate protease activity involved in amyloid precursor protein catabolism|downregulation of aspartyl protease activity involved in amyloid precursor protein degradation|downregulation of aspartic-type endopeptidase activity involved in amyloid precursor protein breakdown|down-regulation of aspartate protease activity involved in amyloid precursor protein degradation|down regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein breakdown|inhibition of carboxyl protease activity involved in amyloid precursor protein breakdown|downregulation of aspartic protease activity involved in APP catabolism|downregulation of aspartic-type endopeptidase activity involved in APP catabolism|downregulation of aspartate protease activity involved in amyloid precursor protein breakdown|inhibition of aspartic endopeptidase activity involved in APP catabolic process|down regulation of aspartic endopeptidase activity involved in amyloid precursor protein catabolic process|downregulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolism|inhibition of aspartate protease activity involved in amyloid precursor protein catabolic process|down regulation of aspartate protease activity involved in amyloid precursor protein degradation|negative regulation of aspartic protease activity involved in amyloid precursor protein breakdown|down regulation of aspartyl protease activity involved in amyloid precursor protein catabolism|negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolism|inhibition of aspartate protease activity involved in amyloid precursor protein catabolism|inhibition of aspartic protease activity involved in amyloid precursor protein catabolic process|down regulation of aspartate protease activity involved in amyloid precursor protein catabolism|negative regulation of aspartyl protease activity involved in amyloid precursor protein catabolism|down-regulation of aspartyl protease activity involved in amyloid precursor protein catabolic process|downregulation of aspartate protease activity involved in amyloid precursor protein degradation|inhibition of aspartic endopeptidase activity involved in APP catabolism|down-regulation of aspartic protease activity involved in APP catabolic process|negative regulation of aspartic endopeptidase activity involved in APP catabolism|down-regulation of aspartate protease activity involved in amyloid precursor protein catabolic process|down-regulation of aspartic endopeptidase activity involved in amyloid precursor protein degradation|downregulation of carboxyl protease activity involved in amyloid precursor protein degradation|downregulation of aspartic protease activity involved in APP catabolic process|down-regulation of carboxyl protease activity involved in amyloid precursor protein catabolism|downregulation of aspartic endopeptidase activity involved in amyloid precursor protein degradation|inhibition of aspartic endopeptidase activity involved in amyloid precursor protein catabolic process|down-regulation of carboxyl protease activity involved in APP catabolism|inhibition of carboxyl protease activity involved in APP catabolism|down regulation of carboxyl protease activity involved in APP catabolic process|inhibition of aspartyl protease activity involved in amyloid precursor protein catabolism|down regulation of aspartic protease activity involved in APP catabolism|down-regulation of aspartate protease activity involved in amyloid precursor protein breakdown|downregulation of aspartic protease activity involved in amyloid precursor protein degradation|inhibition of aspartic protease activity involved in APP catabolism|inhibition of aspartic endopeptidase activity involved in amyloid precursor protein degradation|negative regulation of aspartic protease activity involved in amyloid precursor protein catabolic process|downregulation of aspartic endopeptidase activity involved in amyloid precursor protein breakdown|inhibition of aspartyl protease activity involved in amyloid precursor protein degradation|down regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process|down regulation of aspartic endopeptidase activity involved in APP catabolic process|inhibition of aspartic protease activity involved in APP catabolic process|downregulation of aspartate protease activity involved in APP catabolic process|down-regulation of aspartic endopeptidase activity involved in amyloid precursor protein breakdown|down regulation of aspartic protease activity involved in amyloid precursor protein catabolism|down regulation of aspartic endopeptidase activity involved in APP catabolism|downregulation of aspartyl protease activity involved in APP catabolism|inhibition of aspartate protease activity involved in amyloid precursor protein degradation|downregulation of aspartyl protease activity involved in amyloid precursor protein breakdown|down-regulation of aspartic-type endopeptidase activity involved in APP catabolism|down regulation of aspartic-type endopeptidase activity involved in APP catabolism|negative regulation of aspartyl protease activity involved in APP catabolism|down regulation of carboxyl protease activity involved in APP catabolism|downregulation of aspartyl protease activity involved in APP catabolic process|down regulation of carboxyl protease activity involved in amyloid precursor protein catabolism|negative regulation of carboxyl protease activity involved in APP catabolic process|down-regulation of aspartic protease activity involved in amyloid precursor protein degradation|negative regulation of aspartate protease activity involved in APP catabolic process|inhibition of aspartic protease activity involved in amyloid precursor protein breakdown|down regulation of aspartyl protease activity involved in APP catabolic process|inhibition of carboxyl protease activity involved in amyloid precursor protein degradation|negative regulation of aspartic endopeptidase activity involved in amyloid precursor protein breakdown|negative regulation of aspartyl protease activity involved in amyloid precursor protein degradation|negative regulation of aspartate protease activity involved in amyloid precursor protein catabolism|negative regulation of aspartate protease activity involved in amyloid precursor protein breakdown|downregulation of aspartyl protease activity involved in amyloid precursor protein catabolic process|inhibition of aspartyl protease activity involved in amyloid precursor protein catabolic process|inhibition of aspartic protease activity involved in amyloid precursor protein catabolism|down regulation of aspartic protease activity involved in amyloid precursor protein catabolic process|down regulation of aspartate protease activity involved in amyloid precursor protein breakdown|down-regulation of aspartate protease activity involved in APP catabolism|down-regulation of carboxyl protease activity involved in APP catabolic process|inhibition of aspartyl protease activity involved in APP catabolic process|down regulation of aspartic protease activity involved in amyloid precursor protein breakdown|down regulation of aspartate protease activity involved in APP catabolism|inhibition of aspartyl protease activity involved in amyloid precursor protein breakdown|negative regulation of aspartic endopeptidase activity involved in APP catabolic process|negative regulation of aspartyl protease activity involved in amyloid precursor protein breakdown|downregulation of aspartic endopeptidase activity involved in APP catabolism|inhibition of aspartic endopeptidase activity involved in amyloid precursor protein breakdown|downregulation of aspartic endopeptidase activity involved in amyloid precursor protein catabolic process|down regulation of carboxyl protease activity involved in amyloid precursor protein catabolic process|negative regulation of aspartic protease activity involved in APP catabolic process|inhibition of aspartic endopeptidase activity involved in amyloid precursor protein catabolism|inhibition of carboxyl protease activity involved in amyloid precursor protein catabolism|down-regulation of aspartic protease activity involved in amyloid precursor protein breakdown|downregulation of aspartic endopeptidase activity involved in amyloid precursor protein catabolism|negative regulation of aspartic-type endopeptidase activity involved in APP catabolism|down-regulation of aspartyl protease activity involved in APP catabolic process|down-regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolism|negative regulation of aspartic protease activity involved in amyloid precursor protein degradation|downregulation of carboxyl protease activity involved in amyloid precursor protein breakdown|down regulation of aspartyl protease activity involved in amyloid precursor protein catabolic process|negative regulation of carboxyl protease activity involved in amyloid precursor protein breakdown|down-regulation of aspartic endopeptidase activity involved in APP catabolism|negative regulation of carboxyl protease activity involved in amyloid precursor protein degradation|negative regulation of aspartic-type endopeptidase activity involved in APP catabolic process|inhibition of aspartate protease activity involved in amyloid precursor protein breakdown|down-regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein degradation|inhibition of aspartate protease activity involved in APP catabolism|downregulation of carboxyl protease activity involved in amyloid precursor protein catabolic process|down regulation of aspartyl protease activity involved in APP catabolism|downregulation of carboxyl protease activity involved in APP catabolism|negative regulation of aspartyl protease activity involved in amyloid precursor protein catabolic process|negative regulation of aspartate protease activity involved in amyloid precursor protein catabolic process|down-regulation of carboxyl protease activity involved in amyloid precursor protein breakdown|negative regulation of aspartic protease activity involved in APP catabolism|down-regulation of aspartic-type endopeptidase activity involved in APP catabolic process|negative regulation of aspartic protease activity involved in amyloid precursor protein catabolism|down-regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process|down-regulation of aspartic endopeptidase activity involved in amyloid precursor protein catabolism|down-regulation of aspartic protease activity involved in APP catabolism|down-regulation of aspartic endopeptidase activity involved in APP catabolic process|down regulation of aspartic-type endopeptidase activity involved in APP catabolic process|down regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolism|inhibition of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolism|down-regulation of aspartic endopeptidase activity involved in amyloid precursor protein catabolic process|down regulation of aspartic endopeptidase activity involved in amyloid precursor protein degradation|negative regulation of aspartic endopeptidase activity involved in amyloid precursor protein catabolic process|down-regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein breakdown|negative regulation of carboxyl protease activity involved in amyloid precursor protein catabolic process|inhibition of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process|down regulation of aspartate protease activity involved in amyloid precursor protein catabolic process|inhibition of aspartate protease activity involved in APP catabolic process|inhibition of carboxyl protease activity involved in amyloid precursor protein catabolic process|downregulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process|down regulation of carboxyl protease activity involved in amyloid precursor protein breakdown|negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein breakdown|down-regulation of aspartyl protease activity involved in APP catabolism|downregulation of aspartate protease activity involved in APP catabolism|negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein degradation|downregulation of aspartic-type endopeptidase activity involved in amyloid precursor protein degradation|down-regulation of carboxyl protease activity involved in amyloid precursor protein degradation|negative regulation of aspartic endopeptidase activity involved in amyloid precursor protein degradation|downregulation of carboxyl protease activity involved in APP catabolic process|inhibition of aspartic-type endopeptidase activity involved in APP catabolic process|negative regulation of aspartyl protease activity involved in APP catabolic process|downregulation of aspartic protease activity involved in amyloid precursor protein catabolism|down-regulation of aspartyl protease activity involved in amyloid precursor protein catabolism|downregulation of aspartic protease activity involved in amyloid precursor protein catabolic process|inhibition of aspartic protease activity involved in amyloid precursor protein degradation|negative regulation of aspartate protease activity involved in amyloid precursor protein degradation|down regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein degradation|negative regulation of carboxyl protease activity involved in APP catabolism|downregulation of aspartate protease activity involved in amyloid precursor protein catabolic process|negative regulation of carboxyl protease activity involved in amyloid precursor protein catabolism|down-regulation of carboxyl protease activity involved in amyloid precursor protein catabolic process|down-regulation of aspartate protease activity involved in APP catabolic process|downregulation of aspartic-type endopeptidase activity involved in APP catabolic process|inhibition of aspartyl protease activity involved in APP catabolism|inhibition of aspartic-type endopeptidase activity involved in APP catabolism|down regulation of aspartic endopeptidase activity involved in amyloid precursor protein catabolism|inhibition of carboxyl protease activity involved in APP catabolic process|down regulation of aspartic endopeptidase activity involved in amyloid precursor protein breakdown|negative regulation of aspartic endopeptidase activity involved in amyloid precursor protein catabolism|down-regulation of aspartic protease activity involved in amyloid precursor protein catabolic process|inhibition of aspartic-type endopeptidase activity involved in amyloid precursor protein breakdown							sjp	2014-05-06T09:07:11Z					biological_process											owl:Class	
GO:0060815	biolink:NamedThing	regulation of translation involved in anterior/posterior axis specification	Any process that modulates the frequency, rate or extent of translation of mRNAs that contribute to the specification of the anterior/posterior axis.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-08-07T10:02:31Z					biological_process											owl:Class	
GO:0051920	biolink:NamedThing	peroxiredoxin activity	Catalysis of the reaction: 2 R'-SH + ROOH = R'-S-S-R' + H2O + ROH.	tmpzr1t_l9r_go_relaxed.owl	Prx activity|alkyl hydroperoxide reductase C22 activity|PRDX activity|thiol-containing-reductant:hydroperoxide oxidoreductase activity|AhpC activity				EC:1.11.1.24|RHEA:10008|Reactome:R-HSA-1222431|MetaCyc:1.11.1.15-RXN|Reactome:R-HSA-1500804|Reactome:R-HSA-1222755	Includes redox chemistry as part of the catalytic reaction (2 R'-SH = R'-S-S-R'), where R' refers to peroxiredoxin itself). Not to be confused with GO:0004601 (peroxidase activity, EC:1.11.1.7), which has a different reaction mechanism.								molecular_function											owl:Class	
GO:0021862	biolink:NamedThing	early neuron differentiation in forebrain	The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of neurons. Differentiation includes the processes involved in commitment of a cell to a specific fate.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0021879	biolink:NamedThing	forebrain neuron differentiation	The process in which a relatively unspecialized cell acquires specialized features of a neuron that will reside in the forebrain.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0009056	biolink:NamedThing	catabolic process	The chemical reactions and pathways resulting in the breakdown of substances, including the breakdown of carbon compounds with the liberation of energy for use by the cell or organism.	tmpzr1t_l9r_go_relaxed.owl	catabolism|breakdown|single-organism catabolic process|degradation|multicellular organismal catabolic process				Wikipedia:Catabolism			jl	2012-10-17T15:52:35Z			GO:0044712|GO:0044243		biological_process											owl:Class	
GO:0007591	biolink:NamedThing	molting cycle, chitin-based cuticle	The periodic shedding of part or all of a chitin-based cuticle, which is then replaced by a new cuticle. An example of this is found in Drosophila melanogaster.	tmpzr1t_l9r_go_relaxed.owl	chitin-based cuticle molting cycle													biological_process											owl:Class	
GO:0042303	biolink:NamedThing	molting cycle	The periodic casting off and regeneration of an outer covering of cuticle, feathers, hair, horns, skin, etc.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0033273	biolink:NamedThing	response to vitamin	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin stimulus.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0035332	biolink:NamedThing	positive regulation of hippo signaling	Any process that activates or increases the frequency, rate or extent of hippo signaling.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of hippo signalling cascade|positive regulation of hippo signaling cascade|positive regulation of hippo signaling pathway							bf	2010-02-26T10:54:59Z					biological_process											owl:Class	
GO:1902533	biolink:NamedThing	positive regulation of intracellular signal transduction	Any process that activates or increases the frequency, rate or extent of intracellular signal transduction.	tmpzr1t_l9r_go_relaxed.owl	up regulation of signal transmission via intracellular cascade|positive regulation of signal transduction via intracellular signaling cascade|up regulation of intracellular signaling pathway|activation of intracellular signal transduction pathway|upregulation of intracellular signal transduction pathway|up-regulation of intracellular signaling pathway|positive regulation of intracellular protein kinase cascade|upregulation of intracellular signaling cascade|up-regulation of signal transmission via intracellular cascade|up regulation of signal transduction via intracellular signaling cascade|up regulation of intracellular signaling cascade|positive regulation of signal transmission via intracellular cascade|upregulation of signal transduction via intracellular signaling cascade|up-regulation of signal transduction via intracellular signaling cascade|activation of signal transduction via intracellular signaling cascade|upregulation of signal transmission via intracellular cascade|up-regulation of intracellular signal transduction pathway|up regulation of intracellular signal transduction pathway|positive regulation of intracellular signaling pathway|positive regulation of intracellular signaling chain|activation of signal transmission via intracellular cascade|positive regulation of intracellular signaling cascade|upregulation of intracellular signaling pathway|up-regulation of intracellular signal transduction|up-regulation of intracellular signaling chain|upregulation of intracellular signal transduction|upregulation of intracellular signaling chain|up regulation of intracellular signal transduction|activation of intracellular signaling chain|activation of intracellular signaling pathway|activation of intracellular signaling cascade|up regulation of intracellular signaling chain|up-regulation of intracellular signaling cascade|positive regulation of intracellular signal transduction pathway|activation of intracellular signal transduction							bf	2013-12-02T11:33:10Z			GO:0010740		biological_process											owl:Class	
GO:0090364	biolink:NamedThing	regulation of proteasome assembly	Any process that modulates the rate, frequency, or extent of the aggregation, arrangement and bonding together of a mature, active proteasome complex.	tmpzr1t_l9r_go_relaxed.owl								tb	2010-07-12T10:55:21Z					biological_process											owl:Class	
GO:1905683	biolink:NamedThing	peroxisome disassembly	The disaggregation of a peroxisome into its constituent components.	tmpzr1t_l9r_go_relaxed.owl	peroxisomal disassembly							pr	2016-11-14T10:09:15Z					biological_process											owl:Class	
GO:1903008	biolink:NamedThing	organelle disassembly	The disaggregation of an organelle into its constituent components.	tmpzr1t_l9r_go_relaxed.owl	organelle degradation							jl	2014-05-13T12:36:03Z					biological_process											owl:Class	
GO:0045312	biolink:NamedThing	nor-spermidine biosynthetic process	The chemical reactions and pathways resulting in the formation of nor-spermidine, a compound related to spermidine, N-(3-aminopropyl)-1,4-diaminobutane.	tmpzr1t_l9r_go_relaxed.owl	nor-spermidine anabolism|nor-spermidine formation|nor-spermidine biosynthesis|nor-spermidine synthesis													biological_process											owl:Class	
GO:0046204	biolink:NamedThing	nor-spermidine metabolic process	The chemical reactions and pathways involving nor-spermidine, a compound related to spermidine, N-(3-aminopropyl)-1,4-diaminobutane.	tmpzr1t_l9r_go_relaxed.owl	nor-spermidine metabolism													biological_process											owl:Class	
GO:1900185	biolink:NamedThing	positive regulation of xanthone-containing compound biosynthetic process	Any process that activates or increases the frequency, rate or extent of xanthone-containing compound biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	up regulation of xanthone-containing compound synthesis|activation of xanthone-containing compound biosynthetic process|upregulation of xanthone-containing compound formation|activation of xanthone-containing compound formation|upregulation of xanthone-containing compound synthesis|activation of xanthone biosynthetic process|up-regulation of xanthone-containing compound synthesis|up regulation of xanthone-containing compound biosynthesis|positive regulation of xanthone biosynthetic process|activation of xanthone-containing compound synthesis|positive regulation of xanthone-containing compound synthesis|up-regulation of xanthone-containing compound biosynthetic process|upregulation of xanthone-containing compound biosynthesis|up-regulation of xanthone-containing compound biosynthesis|upregulation of xanthone biosynthesis|up regulation of xanthone-containing compound anabolism|up regulation of xanthone-containing compound biosynthetic process|up regulation of xanthone-containing compound formation|up-regulation of xanthone-containing compound formation|positive regulation of xanthone-containing compound biosynthesis|upregulation of xanthone biosynthetic process|positive regulation of xanthone-containing compound formation|positive regulation of xanthone-containing compound anabolism|up-regulation of xanthone biosynthesis|up-regulation of xanthone-containing compound anabolism|positive regulation of xanthone biosynthesis|up-regulation of xanthone biosynthetic process|upregulation of xanthone-containing compound anabolism|upregulation of xanthone-containing compound biosynthetic process|activation of xanthone biosynthesis|up regulation of xanthone biosynthesis|activation of xanthone-containing compound biosynthesis|activation of xanthone-containing compound anabolism|up regulation of xanthone biosynthetic process							di	2012-03-16T03:30:32Z					biological_process											owl:Class	
GO:1900183	biolink:NamedThing	regulation of xanthone-containing compound biosynthetic process	Any process that modulates the frequency, rate or extent of xanthone-containing compound biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of xanthone-containing compound anabolism|regulation of xanthone-containing compound biosynthesis|regulation of xanthone-containing compound synthesis|regulation of xanthone biosynthesis|regulation of xanthone biosynthetic process|regulation of xanthone-containing compound formation							di	2012-03-16T03:30:14Z					biological_process											owl:Class	
GO:0019607	biolink:NamedThing	phenylethylamine catabolic process	The chemical reactions and pathways resulting in the breakdown of phenylethylamine, an amine with pharmacological properties similar to those of amphetamine, occurs naturally as a neurotransmitter in the brain, and is present in chocolate and oil of bitter almonds.	tmpzr1t_l9r_go_relaxed.owl	phenylethylamine catabolism|phenylethylamine breakdown|phenylethylamine degradation				MetaCyc:2PHENDEG-PWY									biological_process											owl:Class	
GO:0042402	biolink:NamedThing	cellular biogenic amine catabolic process	The chemical reactions and pathways occurring at the level of individual cells resulting in the breakdown of biogenic amines, any of a group of naturally occurring, biologically active amines, such as norepinephrine, histamine, and serotonin, many of which act as neurotransmitters.	tmpzr1t_l9r_go_relaxed.owl	biogenic amine breakdown|biogenic amine degradation|biogenic amine catabolism													biological_process											owl:Class	
GO:1903206	biolink:NamedThing	negative regulation of hydrogen peroxide-induced cell death	Any process that stops, prevents or reduces the frequency, rate or extent of hydrogen peroxide-induced cell death.	tmpzr1t_l9r_go_relaxed.owl	down regulation of cell death in response to H2O2|protection against hydrogen peroxide-induced cell death|down-regulation of cell death in response to H2O2|downregulation of cell death in response to hydrogen peroxide|protection against H2O2-induced cell death|downregulation of cell death in response to H2O2|inhibition of cell death in response to hydrogen peroxide|negative regulation of cell death in response to hydrogen peroxide|downregulation of hydrogen peroxide-mediated cell death|down-regulation of cell death in response to hydrogen peroxide|inhibition of hydrogen peroxide-mediated cell death|negative regulation of hydrogen peroxide-mediated cell death|inhibition of cell death in response to H2O2|down-regulation of hydrogen peroxide-mediated cell death|down regulation of hydrogen peroxide-mediated cell death|negative regulation of cell death in response to H2O2|down regulation of cell death in response to hydrogen peroxide							bf	2014-07-21T16:21:53Z					biological_process											owl:Class	
GO:1901032	biolink:NamedThing	negative regulation of response to reactive oxygen species	Any process that stops, prevents or reduces the frequency, rate or extent of response to reactive oxygen species.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of response to reactive oxygen intermediate|down-regulation of response to ROI|down regulation of response to AOS|down-regulation of response to reactive oxygen species|inhibition of response to ROI|negative regulation of response to AOS|down regulation of response to active oxygen species|inhibition of response to reactive oxygen species|down-regulation of response to active oxygen species|downregulation of response to AOS|inhibition of response to reactive oxidative species|negative regulation of response to ROI|down regulation of response to reactive oxygen intermediate|down regulation of response to reactive oxidative species|down regulation of response to reactive oxygen species|down-regulation of response to reactive oxidative species|down-regulation of response to AOS|negative regulation of response to reactive oxygen intermediate|negative regulation of response to ROS|inhibition of response to AOS|downregulation of response to ROI|negative regulation of response to reactive oxidative species|down regulation of response to ROS|inhibition of response to active oxygen species|down-regulation of response to ROS|inhibition of response to ROS|inhibition of response to reactive oxygen intermediate|downregulation of response to reactive oxidative species|downregulation of response to reactive oxygen intermediate|down regulation of response to ROI|downregulation of response to active oxygen species|downregulation of response to reactive oxygen species|negative regulation of response to active oxygen species|downregulation of response to ROS							kmv	2012-06-20T07:47:28Z					biological_process											owl:Class	
GO:0103033	biolink:NamedThing	beta-galactosidase activity (lactose isomerization)	Catalysis of the reaction: alpha-lactose = beta-(1->6)-galactobiose.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN0-5363									molecular_function											owl:Class	
GO:0016867	biolink:NamedThing	intramolecular transferase activity, transferring acyl groups	Catalysis of the transfer of an acyl group from one position to another within a single molecule.	tmpzr1t_l9r_go_relaxed.owl					EC:5.4.1.-									molecular_function											owl:Class	
GO:0035819	biolink:NamedThing	positive regulation of renal sodium excretion by pressure natriuresis	An increase in the amount of sodium excreted in urine over a unit of time, as a result of pressure natriuresis.	tmpzr1t_l9r_go_relaxed.owl	natriuresis resulting from pressure natriuresis							bf	2011-04-20T01:57:20Z					biological_process											owl:Class	
GO:0035815	biolink:NamedThing	positive regulation of renal sodium excretion	Any process that increases the amount of sodium excreted in urine over a unit of time.	tmpzr1t_l9r_go_relaxed.owl	natriuresis					The amount of sodium excreted in urine over a unit of time can be increased by increasing the volume of urine produced (diuresis) and/or by increasing the concentration of sodium in the urine.		bf	2011-04-20T01:29:26Z					biological_process											owl:Class	
GO:0017064	biolink:NamedThing	fatty acid amide hydrolase activity	Catalysis of the hydrolysis of a fatty acid amide to yield a fatty acid.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-5693742|Reactome:R-HSA-5693751							GO:0017073		molecular_function											owl:Class	
GO:0090510	biolink:NamedThing	anticlinal cell division	A cell division process where the division plane is perpendicular to the surface of the organ. It adds cells to the existing cell layer or cell file.	tmpzr1t_l9r_go_relaxed.owl								tb	2012-11-21T11:52:40Z					biological_process											owl:Class	
GO:0051301	biolink:NamedThing	cell division	The process resulting in division and partitioning of components of a cell to form more cells; may or may not be accompanied by the physical separation of a cell into distinct, individually membrane-bounded daughter cells.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Cell_division	Note that this term differs from 'cytokinesis ; GO:0000910' in that cytokinesis does not include nuclear division.								biological_process											owl:Class	
GO:0060674	biolink:NamedThing	placenta blood vessel development	The process whose specific outcome is the progression of a blood vessel of the placenta over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-06-02T01:09:43Z					biological_process											owl:Class	
GO:0051933	biolink:NamedThing	amino acid neurotransmitter reuptake	The uptake of amino acid neurotransmitters by neurons or glial cells. This process leads to inactivation and recycling of neurotransmitters.	tmpzr1t_l9r_go_relaxed.owl	amino acid neurotransmitter recycling|amino acid uptake during transmission of nerve impulse|amino acid neurotransmitter import into glial cell|amino acid neurotransmitter import into neuron													biological_process											owl:Class	
GO:0043090	biolink:NamedThing	amino acid import	The directed movement of amino acids into a cell or organelle.	tmpzr1t_l9r_go_relaxed.owl	amino acid uptake													biological_process											owl:Class	
GO:1904942	biolink:NamedThing	regulation of cardiac ventricle formation	Any process that modulates the frequency, rate or extent of cardiac ventricle formation.	tmpzr1t_l9r_go_relaxed.owl								bc	2016-02-02T16:37:16Z					biological_process											owl:Class	
GO:2000623	biolink:NamedThing	negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	Any process that stops, prevents or reduces the frequency, rate or extent of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of nuclear mRNA catabolic process, nonsense-mediated decay|negative regulation of mRNA catabolism, nonsense-mediated|negative regulation of mRNA breakdown, nonsense-mediated decay|negative regulation of nonsense-mediated mRNA decay|negative regulation of mRNA degradation, nonsense-mediated decay|negative regulation of mRNA catabolic process, nonsense-mediated							pr	2011-04-18T03:32:46Z					biological_process											owl:Class	
GO:2000622	biolink:NamedThing	regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	Any process that modulates the frequency, rate or extent of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay.	tmpzr1t_l9r_go_relaxed.owl	regulation of nonsense-mediated mRNA decay|regulation of mRNA breakdown, nonsense-mediated decay|regulation of nuclear mRNA catabolic process, nonsense-mediated decay|regulation of mRNA catabolism, nonsense-mediated|regulation of mRNA catabolic process, nonsense-mediated|regulation of mRNA degradation, nonsense-mediated decay							pr	2011-04-18T03:32:42Z					biological_process											owl:Class	
GO:0046576	biolink:NamedThing	rhamnogalacturonan alpha-L-rhamnopyranosyl-(1->4)-alpha-D-galactopyranosyluronide lyase activity	Catalysis of the cleavage of rhamnogalacturonan, generating oligosaccharides of the form alpha-D-us-galacturonic acid-(1,2)-alpha-L-rhamnose-(1,4)-alpha-D-galacturonate-(1,2)-L-rhamnose-(1,2)-alpha-L-rhamnose-p-(1,4)-alpha-D-galacturonic acid, terminating at the non-reducing end with a hex-4-enopyranosyluronic acid residue.	tmpzr1t_l9r_go_relaxed.owl	rhamnogalacturonase B activity													molecular_function											owl:Class	
GO:0060283	biolink:NamedThing	negative regulation of oocyte development	Any process that decreases the rate or extent of the process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0060281	biolink:NamedThing	regulation of oocyte development	Any process that modulates the rate or extent of the process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1904814	biolink:NamedThing	regulation of protein localization to chromosome, telomeric region	Any process that modulates the frequency, rate or extent of protein localization to chromosome, telomeric region.	tmpzr1t_l9r_go_relaxed.owl	regulation of protein localization to telomere|regulation of protein localisation to chromosome, telomeric region							nc	2015-11-16T12:18:43Z					biological_process											owl:Class	
GO:0052086	biolink:NamedThing	suppression by symbiont of host B-cell mediated immune response	Any process in which a symbiont stops, prevents, or reduces the frequency, rate or extent of the B-cell mediated immune response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	down-regulation by symbiont of host B-cell mediated immune response|negative regulation by organism of B-cell mediated immune response of other organism involved in symbiotic interaction|downregulation by symbiont of host B-cell mediated immune response|inhibition by symbiont of host B-cell mediated immune response|down regulation by symbiont of host B-cell mediated immune response											GO:0052281		biological_process											owl:Class	
GO:0052154	biolink:NamedThing	modulation by symbiont of host B-cell mediated immune response	Any process in which a symbiont modulates the frequency, rate or extent of the B-cell mediated immune response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	regulation by organism of host B-cell mediated immune response|modulation by organism of B-cell mediated immune response of other organism involved in symbiotic interaction											GO:0052293		biological_process											owl:Class	
GO:1902083	biolink:NamedThing	negative regulation of peptidyl-cysteine S-nitrosylation	Any process that stops, prevents or reduces the frequency, rate or extent of peptidyl-cysteine S-nitrosylation.	tmpzr1t_l9r_go_relaxed.owl	down regulation of protein S-nitrosylation|negative regulation of S-nitrosylation|downregulation of peptidyl-cysteine S-nitrosylation|down-regulation of S-nitrosylation|down-regulation of peptidyl-cysteine S-nitrosylation|inhibition of S-nitrosylation|down regulation of peptidyl-cysteine S-nitrosylation|down-regulation of protein S-nitrosylation|inhibition of peptidyl-cysteine S-nitrosylation|downregulation of S-nitrosylation|downregulation of protein S-nitrosylation|inhibition of protein S-nitrosylation|negative regulation of protein S-nitrosylation|down regulation of S-nitrosylation							rl	2013-04-24T16:49:34Z					biological_process											owl:Class	
GO:2000169	biolink:NamedThing	regulation of peptidyl-cysteine S-nitrosylation	Any process that modulates the frequency, rate or extent of peptidyl-cysteine S-nitrosylation.	tmpzr1t_l9r_go_relaxed.owl								rl	2010-10-07T10:49:32Z					biological_process											owl:Class	
GO:0009080	biolink:NamedThing	pyruvate family amino acid catabolic process	The chemical reactions and pathways resulting in the breakdown of any amino acid that requires pyruvate for its synthesis, e.g. alanine.	tmpzr1t_l9r_go_relaxed.owl	pyruvate family amino acid catabolism|pyruvate family amino acid breakdown|pyruvate family amino acid degradation													biological_process											owl:Class	
GO:0010238	biolink:NamedThing	response to proline	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a proline stimulus.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0015910	biolink:NamedThing	long-chain fatty acid import into peroxisome	The directed movement of long-chain fatty acids into a peroxisome. A long-chain fatty acid is a fatty acid with a chain length between C13 and C22.	tmpzr1t_l9r_go_relaxed.owl	peroxisomal long-chain fatty acid import|peroxisomal long-chain fatty acid uptake													biological_process											owl:Class	
GO:0015909	biolink:NamedThing	long-chain fatty acid transport	The directed movement of long-chain fatty acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A long-chain fatty acid is a fatty acid with a chain length between C13 and C22.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0010020	biolink:NamedThing	chloroplast fission	The division of a chloroplast within a cell to form two or more separate chloroplast compartments. This division occurs independently of mitosis.	tmpzr1t_l9r_go_relaxed.owl	chloroplast division													biological_process											owl:Class	
GO:0043572	biolink:NamedThing	plastid fission	The creation of two or more plastids by division of one plastid. A plastid is any member of a family of organelles found in the cytoplasm of plants and some protists, which are membrane-bounded and contain DNA.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0033268	biolink:NamedThing	node of Ranvier	An axon part that is a gap in the myelin where voltage-gated sodium channels cluster and saltatory conduction is executed.	tmpzr1t_l9r_go_relaxed.owl	node of Ranvier axon				Wikipedia:Nodes_of_Ranvier|NIF_Subcellular:birnlex_1152_2									cellular_component											owl:Class	
GO:0070508	biolink:NamedThing	cholesterol import	The directed movement of cholesterol into a cell or organelle.	tmpzr1t_l9r_go_relaxed.owl	cholesterol uptake													biological_process											owl:Class	
GO:0035376	biolink:NamedThing	sterol import	The directed movement of a sterol into a cell or organelle. Sterols are steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule.	tmpzr1t_l9r_go_relaxed.owl	sterol uptake|sterol influx							bf	2010-03-18T10:53:01Z					biological_process											owl:Class	
GO:0014067	biolink:NamedThing	negative regulation of phosphatidylinositol 3-kinase signaling	Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the phosphatidylinositol 3-kinase cascade.	tmpzr1t_l9r_go_relaxed.owl	down regulation of phosphatidylinositol 3-kinase cascade|negative regulation of PI3K cascade|inhibition of phosphatidylinositol 3-kinase cascade|negative regulation of PI 3-kinase cascade|negative regulation of phosphoinositide 3-kinase cascade|downregulation of phosphatidylinositol 3-kinase cascade|down-regulation of phosphatidylinositol 3-kinase cascade|negative regulation of phosphatidylinositol 3-kinase cascade													biological_process											owl:Class	
GO:1900982	biolink:NamedThing	positive regulation of phenazine biosynthetic process	Any process that activates or increases the frequency, rate or extent of phenazine biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of azophenylene biosynthesis|up-regulation of acridizine biosynthetic process|up-regulation of azophenylene biosynthesis|up regulation of azophenylene biosynthesis|up regulation of dibenzopyrazine biosynthesis|activation of dibenzopyrazine biosynthesis|upregulation of dibenzo-p-diazine biosynthetic process|upregulation of acridizine biosynthetic process|activation of phenazine biosynthetic process|up-regulation of dibenzopyrazine biosynthetic process|activation of acridizine biosynthesis|up regulation of acridizine biosynthesis|activation of dibenzo-p-diazine biosynthetic process|up-regulation of phenazine biosynthetic process|up-regulation of dibenzo-p-diazine biosynthesis|up regulation of acridizine biosynthetic process|upregulation of azophenylene biosynthetic process|up-regulation of azophenylene biosynthetic process|positive regulation of dibenzo-p-diazine biosynthetic process|positive regulation of dibenzo-p-diazine biosynthesis|upregulation of phenazine biosynthetic process|upregulation of azophenylene biosynthesis|positive regulation of acridizine biosynthesis|up-regulation of acridizine biosynthesis|positive regulation of azophenylene biosynthetic process|positive regulation of acridizine biosynthetic process|upregulation of acridizine biosynthesis|up-regulation of dibenzo-p-diazine biosynthetic process|up regulation of dibenzo-p-diazine biosynthetic process|activation of azophenylene biosynthesis|up-regulation of dibenzopyrazine biosynthesis|upregulation of dibenzopyrazine biosynthetic process|activation of dibenzo-p-diazine biosynthesis|activation of azophenylene biosynthetic process|upregulation of dibenzo-p-diazine biosynthesis|activation of dibenzopyrazine biosynthetic process|up regulation of dibenzopyrazine biosynthetic process|up regulation of dibenzo-p-diazine biosynthesis|positive regulation of dibenzopyrazine biosynthetic process|up regulation of phenazine biosynthetic process|up regulation of azophenylene biosynthetic process|activation of acridizine biosynthetic process|upregulation of dibenzopyrazine biosynthesis|positive regulation of dibenzopyrazine biosynthesis							tt	2012-06-14T04:05:10Z					biological_process											owl:Class	
GO:0060695	biolink:NamedThing	negative regulation of cholesterol transporter activity	Any process that decreases the rate, frequency, or extent of cholesterol transporter activity.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-06-08T02:08:34Z					biological_process											owl:Class	
GO:0035484	biolink:NamedThing	adenine/adenine mispair binding	Binding to a double-stranded DNA region containing an A/A mispair.	tmpzr1t_l9r_go_relaxed.owl	A/A mispair binding							bf	2010-04-23T10:54:52Z					molecular_function											owl:Class	
GO:0030983	biolink:NamedThing	mismatched DNA binding	Binding to a double-stranded DNA region containing one or more mismatches.	tmpzr1t_l9r_go_relaxed.owl	mispair binding|mispaired DNA binding											GO:0032134		molecular_function											owl:Class	
GO:0033625	biolink:NamedThing	positive regulation of integrin activation	Any process that activates or increases the frequency, rate, or extent of integrin activation.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of integrin complex activation													biological_process											owl:Class	
GO:0034136	biolink:NamedThing	negative regulation of toll-like receptor 2 signaling pathway	Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 2 signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of TLR2 signaling pathway|negative regulation of toll-like receptor 2 signalling pathway													biological_process											owl:Class	
GO:1901234	biolink:NamedThing	positive regulation of convergent extension involved in axis elongation	Any process that activates or increases the frequency, rate or extent of convergent extension involved in axis elongation.	tmpzr1t_l9r_go_relaxed.owl	up regulation of convergent extension involved in axis elongation|activation of convergent extension involved in axis elongation|upregulation of convergent extension involved in axis elongation|up-regulation of convergent extension involved in axis elongation							vk	2012-08-07T14:22:19Z					biological_process											owl:Class	
GO:0044173	biolink:NamedThing	host cell endoplasmic reticulum-Golgi intermediate compartment membrane	The lipid bilayer surrounding any of the compartments of the host cell ER-Golgi intermediate compartment system.	tmpzr1t_l9r_go_relaxed.owl	host endoplasmic reticulum-Golgi intermediate compartment membrane|host cell ER-Golgi intermediate compartment membrane|host ER-Golgi intermediate compartment membrane							jl	2009-09-04T02:46:13Z					cellular_component											owl:Class	
GO:0033644	biolink:NamedThing	host cell membrane	Double layer of lipid molecules as it encloses host cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:1905948	biolink:NamedThing	ABC-type 3',5'-cyclic GMP transmembrane transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + 3',5'-cyclic GMP(in) = ADP + phosphate + 3',5'-cyclic GMP(out).	tmpzr1t_l9r_go_relaxed.owl	ATPase-coupled 3',5'-cyclic GMP transmembrane transporter activity|3',5'-cyclic GMP transmembrane-transporting ATPase activity|ATP-dependent 3',5'-cyclic GMP transmembrane transporter activity|ATPase-coupled cGMP transmembrane transporter activity							ha	2017-02-16T15:54:51Z					molecular_function											owl:Class	
GO:0032985	biolink:NamedThing	protein-carbohydrate complex disassembly	The disaggregation of a protein-carbohydrate complex into its constituent components.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0071823	biolink:NamedThing	protein-carbohydrate complex subunit organization	Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a protein-carbohydrate complex.	tmpzr1t_l9r_go_relaxed.owl	protein-carbohydrate complex subunit organisation							mah	2010-09-08T10:03:03Z					biological_process											owl:Class	
GO:0047284	biolink:NamedThing	dolichyl-xylosyl-phosphate-protein xylosyltransferase activity	Catalysis of the reaction: dolichyl D-xylosyl phosphate + protein = dolichol-phosphate + D-xylosylprotein.	tmpzr1t_l9r_go_relaxed.owl	dolichyl-D-xylosyl-phosphate:protein D-xylosyltransferase activity				RHEA:18361|MetaCyc:2.4.2.33-RXN|EC:2.4.2.33									molecular_function											owl:Class	
GO:0042285	biolink:NamedThing	xylosyltransferase activity	Catalysis of the transfer of a xylosyl group to an acceptor molecule, typically another carbohydrate or a lipid.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0060988	biolink:NamedThing	lipid tube assembly	The aggregation, arrangement and bonding together of a set of macromolecules to form a macromolecular complex that contains a tube of lipid surrounded by a protein coat involved in membrane shaping of vesicle membranes as they fuse or undergo fission.	tmpzr1t_l9r_go_relaxed.owl	lipid tubulation							dph	2010-01-11T01:56:59Z					biological_process											owl:Class	
GO:0003246	biolink:NamedThing	embryonic cardiac muscle cell growth involved in heart morphogenesis	The growth of a cardiac muscle cell during the embryonic period, that contributes to the shaping of the heart.	tmpzr1t_l9r_go_relaxed.owl	embryonic cardiac muscle physiological hypertrophy							dph	2009-10-13T11:46:23Z					biological_process											owl:Class	
GO:0061049	biolink:NamedThing	cell growth involved in cardiac muscle cell development	The growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state.	tmpzr1t_l9r_go_relaxed.owl	cardiac muscle cell hypertrophy|cardiomyocyte growth|heart muscle cell growth							dph	2010-02-25T12:56:07Z					biological_process											owl:Class	
GO:0036012	biolink:NamedThing	cyanelle inner membrane	The inner, i.e. lumen-facing, lipid bilayer of the cyanelle envelope; also faces the cyanelle stroma.	tmpzr1t_l9r_go_relaxed.owl	cyanelle inner envelope membrane							bf	2011-10-10T01:48:56Z					cellular_component											owl:Class	
GO:0009528	biolink:NamedThing	plastid inner membrane	The inner, i.e. lumen-facing, lipid bilayer of the plastid envelope; also faces the plastid stroma.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0032969	biolink:NamedThing	endosomal scaffold complex	A protein complex that contains MAPKSP1 (MP1, Map2k1ip1) and ROBLD3 (p14, Mapbpip), is anchored to late endosomes, and is involved in selective activation of the ERK1 in ERK/MAPK signaling.	tmpzr1t_l9r_go_relaxed.owl	MP1-p14 scaffolding complex|endosomal adaptor complex													cellular_component											owl:Class	
GO:0042413	biolink:NamedThing	carnitine catabolic process	The chemical reactions and pathways resulting in the breakdown of carnitine (hydroxy-trimethyl aminobutyric acid), a compound that participates in the transfer of acyl groups across the inner mitochondrial membrane.	tmpzr1t_l9r_go_relaxed.owl	vitamin Bt catabolic process|carnitine degradation|vitamin Bt catabolism|carnitine catabolism|carnitine breakdown													biological_process											owl:Class	
GO:0009437	biolink:NamedThing	carnitine metabolic process	The chemical reactions and pathways involving carnitine (hydroxy-trimethyl aminobutyric acid), a compound that participates in the transfer of acyl groups across the inner mitochondrial membrane.	tmpzr1t_l9r_go_relaxed.owl	carnitine metabolism|vitamin Bt metabolism|vitamin Bt metabolic process													biological_process											owl:Class	
GO:1905001	biolink:NamedThing	negative regulation of membrane repolarization during atrial cardiac muscle cell action potential	Any process that stops, prevents or reduces the frequency, rate or extent of membrane repolarization during atrial cardiac muscle cell action potential.	tmpzr1t_l9r_go_relaxed.owl	down regulation of atrial repolarization|inhibition of membrane repolarization during atrial cardiac muscle cell action potential|downregulation of electrocardiogram QRS complex|downregulation of atrial repolarization|negative regulation of electrocardiogram QRS complex|down-regulation of atrial repolarization|down-regulation of membrane repolarization during atrial cardiac muscle cell action potential|down regulation of electrocardiogram QRS complex|downregulation of membrane repolarization during atrial cardiac muscle cell action potential|negative regulation of atrial repolarization|down regulation of membrane repolarization during atrial cardiac muscle cell action potential|down-regulation of electrocardiogram QRS complex|inhibition of atrial repolarization|inhibition of electrocardiogram QRS complex							rph	2016-03-01T13:28:13Z					biological_process											owl:Class	
GO:0006313	biolink:NamedThing	transposition, DNA-mediated	Any process involved in a type of transpositional recombination which occurs via a DNA intermediate.	tmpzr1t_l9r_go_relaxed.owl	Class II transposition|Tc3 transposition|DNA transposition|P-element excision|P-element transposition|Tc1/mariner transposition											GO:0006317|GO:0006318		biological_process											owl:Class	
GO:0010832	biolink:NamedThing	negative regulation of myotube differentiation	Any process that decreases the frequency, rate or extent of myotube differentiation. Myotube differentiation is the process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0010830	biolink:NamedThing	regulation of myotube differentiation	Any process that modulates the frequency, rate or extent of myotube differentiation. Myotube differentiation is the process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1901209	biolink:NamedThing	positive regulation of heart looping	Any process that activates or increases the frequency, rate or extent of heart looping.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of heart looping|activation of cardiac looping|up regulation of heart looping|upregulation of cardiac looping|up-regulation of cardiac looping|up regulation of cardiac looping|upregulation of heart looping|positive regulation of cardiac looping|activation of heart looping							rl	2012-07-31T07:16:18Z					biological_process											owl:Class	
GO:0061041	biolink:NamedThing	regulation of wound healing	Any process that modulates the rate, frequency, or extent of the series of events that restore integrity to a damaged tissue, following an injury.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-02-25T10:14:37Z					biological_process											owl:Class	
GO:0002097	biolink:NamedThing	tRNA wobble base modification	The process in which the nucleotide at position 34 in the anticodon of a tRNA is post-transcriptionally modified.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0038091	biolink:NamedThing	positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway	A series of molecular signals initiated by the binding of a vascular endothelial growth factor (VEGF) to a platelet-derived growth factor receptor (PDGFR) on the surface of a cell, which activates or increases the frequency, rate or extent of cell proliferation.	tmpzr1t_l9r_go_relaxed.owl	VEGF-A-induced cell proliferation|positive regulation of cell proliferation by VEGF/PDGFR signaling pathway|positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signalling pathway							bf	2012-02-02T03:45:49Z					biological_process											owl:Class	
GO:0038086	biolink:NamedThing	VEGF-activated platelet-derived growth factor receptor signaling pathway	A series of molecular signals initiated by the binding of a vascular endothelial growth factor (VEGF) to a platelet-derived growth factor receptor (PDGFR) on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.	tmpzr1t_l9r_go_relaxed.owl	vascular endothelial growth factor-activated platelet-derived growth factor receptor signaling pathway|VEGF-A/PDGFR signaling|VEGF-activated PDGFR signalling pathway|VEGF/PDGFR signaling pathway|VEGF-activated platelet-derived growth factor receptor signalling pathway							bf	2012-02-01T03:05:43Z					biological_process											owl:Class	
GO:0006140	biolink:NamedThing	regulation of nucleotide metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nucleotides.	tmpzr1t_l9r_go_relaxed.owl	regulation of nucleotide metabolism													biological_process											owl:Class	
GO:0070220	biolink:NamedThing	aerobic sulfur oxidation	A sulfur oxidation process that proceeds via the reaction catalyzed by sulfur dioxygenase, and requires the presence of oxygen.	tmpzr1t_l9r_go_relaxed.owl	aerobic sulphur oxidation				MetaCyc:SULFUROX-PWY									biological_process											owl:Class	
GO:0048023	biolink:NamedThing	positive regulation of melanin biosynthetic process	Any process that activates or increases the rate or extent of the chemical reactions and pathways resulting in the formation of melanin.	tmpzr1t_l9r_go_relaxed.owl	stimulation of melanin biosynthetic process|positive regulation of melanin biosynthesis|activation of melanin biosynthetic process|positive regulation of melanin formation|positive regulation of melanin synthesis|up-regulation of melanin biosynthetic process|positive regulation of melanin anabolism|up regulation of melanin biosynthetic process|upregulation of melanin biosynthetic process													biological_process											owl:Class	
GO:0051650	biolink:NamedThing	establishment of vesicle localization	The directed movement of a vesicle to a specific location.	tmpzr1t_l9r_go_relaxed.owl	establishment of vesicle localisation													biological_process											owl:Class	
GO:0060130	biolink:NamedThing	thyroid-stimulating hormone-secreting cell development	The process whose specific outcome is the progression of a thyroid-stimulating hormone-secreting cell over time, from its formation to the mature structure. A thyroid-stimulating hormone-secreting cell is a basophil cell of the anterior pituitary that produces thyroid stimulating hormone, thyrotrophin.	tmpzr1t_l9r_go_relaxed.owl	thyrotrope development|thyroid stimulating hormone secreting cell development|beta-basophil development|thyrotroph development|TSH-secreting cell development													biological_process											owl:Class	
GO:0043481	biolink:NamedThing	anthocyanin accumulation in tissues in response to UV light	The aggregation of the pigment anthocyanin in a particular location in a tissue, occurring in response to a UV light stimulus.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0043479	biolink:NamedThing	pigment accumulation in tissues in response to UV light	The aggregation of coloring matter in a particular location in a tissue, occurring in response to a UV light stimulus.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0061259	biolink:NamedThing	mesonephric glomerular mesangial cell differentiation	The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the glomerular mesangial cells of the mesonephros as it progresses from its formation to the mature state.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-08-30T02:22:45Z					biological_process											owl:Class	
GO:0072008	biolink:NamedThing	glomerular mesangial cell differentiation	The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the glomerular mesangial cells of the kidney as it progresses from its formation to the mature state.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-01-25T01:59:33Z					biological_process											owl:Class	
GO:0009639	biolink:NamedThing	response to red or far red light	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a red or far red light stimulus. Red light is electromagnetic radiation of wavelength of 580-700nm. Far red light is electromagnetic radiation of wavelength 700-800nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reversed by exposure to far red light. During the initial phase the phytochrome molecule is only present in the red light absorbing form, but on absorption of red light it changes to a far red light absorbing form, triggering progress through development. An immediate short period of exposure to far red light entirely returns the pigment to its initial state and prevents triggering of the developmental process. A thirty minute break between red and subsequent far red light exposure renders the red light effect irreversible, and development then occurs regardless of whether far red light exposure subsequently occurs.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1903196	biolink:NamedThing	negative regulation of L-dopa biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of L-dopa biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	inhibition of L-dopa synthesis|inhibition of L-dopa biosynthetic process|inhibition of L-dopa biosynthesis|downregulation of L-dopa biosynthetic process|negative regulation of L-dopa formation|down-regulation of L-dopa biosynthesis|down-regulation of L-dopa synthesis|downregulation of L-dopa biosynthesis|down regulation of L-dopa anabolism|negative regulation of L-dopa biosynthesis|downregulation of L-dopa synthesis|down regulation of L-dopa formation|down regulation of L-dopa biosynthetic process|down-regulation of L-dopa biosynthetic process|down regulation of L-dopa biosynthesis|negative regulation of L-dopa synthesis|down-regulation of L-dopa anabolism|downregulation of L-dopa formation|down regulation of L-dopa synthesis|down-regulation of L-dopa formation|downregulation of L-dopa anabolism|inhibition of L-dopa anabolism|inhibition of L-dopa formation|negative regulation of L-dopa anabolism							bf	2014-07-21T09:12:44Z					biological_process											owl:Class	
GO:1903195	biolink:NamedThing	regulation of L-dopa biosynthetic process	Any process that modulates the frequency, rate or extent of L-dopa biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of L-dopa formation|regulation of L-dopa biosynthesis|regulation of L-dopa synthesis|regulation of L-dopa anabolism							bf	2014-07-21T09:12:37Z					biological_process											owl:Class	
GO:0090205	biolink:NamedThing	positive regulation of cholesterol metabolic process	Any process that increases the rate, frequency, or extent of cholesterol metabolism, the chemical reactions and pathways involving cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-12-23T10:27:37Z					biological_process											owl:Class	
GO:0015948	biolink:NamedThing	methanogenesis	The chemical reactions and pathways resulting in the formation of methane, a colorless, odorless, flammable gas with the formula CH4. It is the simplest of the alkanes.	tmpzr1t_l9r_go_relaxed.owl	methane biosynthetic process|methane biosynthesis				Wikipedia:Methanogenesis|UM-BBD_pathwayID:meth									biological_process											owl:Class	
GO:0015947	biolink:NamedThing	methane metabolic process	The chemical reactions and pathways involving methane, a colorless, odorless, flammable gas with the formula CH4. It is the simplest of the alkanes.	tmpzr1t_l9r_go_relaxed.owl	methane metabolism													biological_process											owl:Class	
GO:0046005	biolink:NamedThing	positive regulation of circadian sleep/wake cycle, REM sleep	Any process that activates or increases the duration or quality of rapid eye movement (REM) sleep.	tmpzr1t_l9r_go_relaxed.owl	stimulation of circadian sleep/wake cycle, REM sleep|positive regulation of REM sleep|up-regulation of circadian sleep/wake cycle, REM sleep|activation of circadian sleep/wake cycle, REM sleep|up regulation of circadian sleep/wake cycle, REM sleep|upregulation of circadian sleep/wake cycle, REM sleep													biological_process											owl:Class	
GO:0002311	biolink:NamedThing	gamma-delta T cell proliferation involved in immune response	The expansion of a gamma-delta T cell population by cell division as part of an immune response.	tmpzr1t_l9r_go_relaxed.owl	gamma-delta T-lymphocyte proliferation during immune response|gamma-delta T lymphocyte proliferation during immune response|gamma-delta T cell proliferation during immune response|gamma-delta T-cell proliferation during immune response													biological_process											owl:Class	
GO:0046630	biolink:NamedThing	gamma-delta T cell proliferation	The expansion of a gamma-delta T cell population by cell division.	tmpzr1t_l9r_go_relaxed.owl	gamma-delta T-lymphocyte proliferation|gamma-delta T lymphocyte proliferation|gamma-delta T-cell proliferation													biological_process											owl:Class	
GO:0007094	biolink:NamedThing	mitotic spindle assembly checkpoint signaling	A signal transduction process that contributes to a mitotic cell cycle spindle assembly checkpoint, that delays the metaphase/anaphase transition of a mitotic nuclear division until the spindle is correctly assembled and chromosomes are attached to the spindle.	tmpzr1t_l9r_go_relaxed.owl	mitotic checkpoint|mitotic cell cycle spindle assembly checkpoint|mitotic spindle assembly checkpoint|signaling cascade involved in SAC-independent checkpoint|mitotic spindle assembly checkpoint signalling|signaling cascade involved in Dma1-dependent checkpoint|signalling cascade involved in Dma1-dependent checkpoint|signalling pathway involved in Dma1-dependent checkpoint|signal transduction involved in SAC-independent checkpoint|Mad2-dependent checkpoint|SAC-independent checkpoint|signal transduction involved in mitotic spindle assembly checkpoint|signalling cascade involved in SAC-independent checkpoint|signaling pathway involved in SAC-independent checkpoint|signal transduction involved in Dma1-dependent checkpoint|signal transduction involved in mitotic cell cycle spindle assembly checkpoint|Dma1-dependent checkpoint|signaling pathway involved in Dma1-dependent checkpoint|signalling pathway involved in SAC-independent checkpoint	https://github.com/geneontology/go-ontology/issues/20935|https://github.com/geneontology/go-ontology/issues/19810										GO:1902420|GO:0072480|GO:0044810		biological_process											owl:Class	
GO:0071174	biolink:NamedThing	mitotic spindle checkpoint signaling	A signaling process that contributes to a mitotic cell cycle checkpoint that originates from the spindle and delays the metaphase/anaphase transition of a mitotic nuclear division until the spindle is correctly assembled and oriented, the completion of anaphase until chromosomes are attached to the spindle, or mitotic exit and cytokinesis when the spindle does not form.	tmpzr1t_l9r_go_relaxed.owl	signal transduction involved in mitotic cell cycle spindle checkpoint|topo II checkpoint|mitotic spindle checkpoint|signal transduction involved in mitotic spindle checkpoint|mitotic cell cycle spindle checkpoint|topoisomerase II checkpoint	https://github.com/geneontology/go-ontology/issues/20935				Note that this term should not be used for direct manual annotation as it should always be possible to specify the type of spindle checkpoint (assembly, orientation checkpoints).		mah	2009-11-23T12:41:36Z			GO:0072477		biological_process											owl:Class	
GO:0016482	biolink:NamedThing	cytosolic transport	The directed movement of substances or organelles within the cytosol.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1901556	biolink:NamedThing	response to candesartan	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a candesartan stimulus.	tmpzr1t_l9r_go_relaxed.owl								hp	2012-11-02T09:46:13Z					biological_process											owl:Class	
GO:0003154	biolink:NamedThing	BMP signaling pathway involved in determination of left/right symmetry	A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, which contributes to the determination of left/right symmetry.	tmpzr1t_l9r_go_relaxed.owl	BMP signalling pathway involved in determination of left/right symmetry|BMP signaling pathway involved in determination of left/right asymmetry							tb	2009-09-24T05:34:57Z					biological_process											owl:Class	
GO:0140097	biolink:NamedThing	catalytic activity, acting on DNA	Catalytic activity that acts to modify DNA.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/14225						pg	2017-09-14T12:03:51Z					molecular_function											owl:Class	
GO:0015519	biolink:NamedThing	D-xylose:proton symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: D-xylose(out) + H+(out) = D-xylose(in) + H+(in).	tmpzr1t_l9r_go_relaxed.owl	D-xylose:hydrogen symporter activity													molecular_function											owl:Class	
GO:0015148	biolink:NamedThing	D-xylose transmembrane transporter activity	Enables the transfer of D-xylose from one side of a membrane to the other. D-xylose (the naturally occurring enantiomer is always D-) is a constituent of plant polysaccharides.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0034924	biolink:NamedThing	cis-3,4-phenanthrenedihydrodiol-4-carboxylate dehydrogenase activity	Catalysis of the reaction: cis-3,4-phenanthrenedihydrodiol-4-carboxylate = 3,4-dihydroxyphenanthrene + H+ + 2 e- + CO2.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0940									molecular_function											owl:Class	
GO:0002917	biolink:NamedThing	regulation of peripheral B cell anergy	Any process that modulates the frequency, rate, or extent of peripheral B cell anergy.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0002712	biolink:NamedThing	regulation of B cell mediated immunity	Any process that modulates the frequency, rate, or extent of B cell mediated immunity.	tmpzr1t_l9r_go_relaxed.owl	regulation of B-cell mediated immunity|regulation of B-lymphocyte mediated immunity|regulation of B lymphocyte mediated immunity													biological_process											owl:Class	
GO:0097531	biolink:NamedThing	mast cell migration	The movement of a mast cell within or between different tissues and organs of the body.	tmpzr1t_l9r_go_relaxed.owl								pr	2013-11-11T14:01:41Z					biological_process											owl:Class	
GO:0036471	biolink:NamedThing	cellular response to glyoxal	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glyoxal stimulus.	tmpzr1t_l9r_go_relaxed.owl								bf	2014-07-21T11:14:33Z					biological_process											owl:Class	
GO:0052104	biolink:NamedThing	induction by symbiont of host systemic acquired resistance	Any process in which a symbiont activates systemic acquired resistance in the host organism; systemic acquired resistance is a salicylic acid-mediated response that confers broad spectrum systemic resistance. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	induction by organism of SAR in host|positive regulation by organism of systemic acquired resistance in other organism involved in symbiotic interaction|positive regulation by symbiont of host systemic acquired resistance|up-regulation by symbiont of systemic acquired resistance in host|up regulation by symbiont of systemic acquired resistance in host|activation by organism of systemic acquired resistance in host|induction by symbiont of systemic acquired resistance in host|induction by organism of systemic acquired resistance in other organism involved in symbiotic interaction|activation by organism of SAR in host|stimulation by symbiont of systemic acquired resistance in host|upregulation by symbiont of systemic acquired resistance in host|positive regulation by symbiont of systemic acquired resistance in host											GO:0052537|GO:0052289|GO:0052535		biological_process											owl:Class	
GO:0052390	biolink:NamedThing	induction by symbiont of host innate immune response	The activation by a symbiont of the innate immune response of the host organism; the innate immune response is the host's first line of defense against infection. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	upregulation by symbiont of host innate immunity|induction by organism of innate immune response in other organism involved in symbiotic interaction|positive regulation of host innate immune response|positive regulation by symbiont of host innate immune response|stimulation by symbiont of host innate immunity|up regulation by symbiont of host innate immunity|induction of host innate immunity|activation by organism of host innate immune response|up-regulation by symbiont of host innate immunity|induction by symbiont of host innate immunity|activation by organism of host innate immunity|positive regulation of innate immune response in other organism|induction by organism of host innate immune response|positive regulation by symbiont of host innate immunity|activation by symbiont of host innate immunity											GO:0052382|GO:0052305|GO:0052166		biological_process											owl:Class	
GO:0000073	biolink:NamedThing	initial mitotic spindle pole body separation	The release of duplicated mitotic spindle pole bodies (SPBs) that begins with the nucleation of microtubules from each SPB within the nucleus, leading to V-shaped spindle microtubules. Interpolar microtubules that elongate from each pole are interconnected, forming overlapping microtubules. Capturing and antiparallel sliding apart of microtubules promotes the initial separation of the SPB.	tmpzr1t_l9r_go_relaxed.owl												GO:0030475		biological_process											owl:Class	
GO:0110100	biolink:NamedThing	spindle pole body separation	The release of duplicated spindle pole bodies (SPBs) and their migration away from each other within the nuclear membrane. Duplicated SPBs are connected by a bridge structure that is severed in order to release the SPBs from one another. Following liberation, SPBs diffuse through the nuclear membrane until they are across from each other. SPB separation must take place in order for a bipolar spindle to assemble.	tmpzr1t_l9r_go_relaxed.owl						Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.		kmv	2018-03-06T15:09:28Z					biological_process											owl:Class	
GO:0032732	biolink:NamedThing	positive regulation of interleukin-1 production	Any process that activates or increases the frequency, rate, or extent of interleukin-1 production.	tmpzr1t_l9r_go_relaxed.owl	stimulation of interleukin-1 production|up regulation of interleukin-1 production|upregulation of interleukin-1 production|up-regulation of interleukin-1 production|positive regulation of IL-1 production|positive regulation of interleukin-1 biosynthetic process|positive regulation of interleukin-1 secretion|activation of interleukin-1 production											GO:0045362|GO:0050716		biological_process											owl:Class	
GO:0006599	biolink:NamedThing	phosphagen metabolic process	The chemical reactions and pathways involving phosphagen, any of a group of guanidine phosphates that occur in muscle and can be used to regenerate ATP from ADP during muscular contraction.	tmpzr1t_l9r_go_relaxed.owl	phosphagen metabolism													biological_process											owl:Class	
GO:0070235	biolink:NamedThing	regulation of activation-induced cell death of T cells	Any process that modulates the occurrence or rate of activation-induced cell death of T cells.	tmpzr1t_l9r_go_relaxed.owl	regulation of activation-induced cell death of T-lymphocytes|regulation of antigen-driven apoptosis|regulation of activation-induced cell death of T-cells|regulation of activated T cell apoptosis|regulation of AICD|regulation of activation-induced cell death of T lymphocytes													biological_process											owl:Class	
GO:0032455	biolink:NamedThing	nerve growth factor processing	The generation of a mature nerve growth factor (NGF) by proteolysis of a precursor.	tmpzr1t_l9r_go_relaxed.owl	NGF processing|beta-nerve growth factor processing													biological_process											owl:Class	
GO:0016486	biolink:NamedThing	peptide hormone processing	The generation of a mature peptide hormone by posttranslational processing of a prohormone.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0036100	biolink:NamedThing	leukotriene catabolic process	The chemical reactions and pathways resulting in the breakdown of a leukotriene, a pharmacologically active substance derived from a polyunsaturated fatty acid, such as arachidonic acid.	tmpzr1t_l9r_go_relaxed.owl	leukotriene degradation|leukotriene catabolism|leukotriene breakdown							bf	2012-01-27T01:26:24Z					biological_process											owl:Class	
GO:0019079	biolink:NamedThing	viral genome replication	Any process involved directly in viral genome replication, including viral nucleotide metabolism.	tmpzr1t_l9r_go_relaxed.owl	viral replication|sigma virus replication													biological_process											owl:Class	
GO:1901407	biolink:NamedThing	regulation of phosphorylation of RNA polymerase II C-terminal domain	Any process that modulates the frequency, rate or extent of phosphorylation of RNA polymerase II C-terminal domain.	tmpzr1t_l9r_go_relaxed.owl	regulation of generation of hyperphosphorylated CTD of RNA polymerase II|regulation of generation of II(0) form of RNA polymerase II|regulation of hyperphosphorylation of RNA polymerase II C-terminal domain|regulation of CTD domain phosphorylation of RNA polymerase II							vw	2012-10-01T14:39:50Z					biological_process											owl:Class	
GO:0036014	biolink:NamedThing	cyanelle intermembrane space	The region between the inner and outer lipid bilayers of the cyanelle envelope; includes the peptidoglycan layer.	tmpzr1t_l9r_go_relaxed.owl	cyanelle periplasm|cyanelle envelope lumen							bf	2011-10-10T02:12:28Z					cellular_component											owl:Class	
GO:0009529	biolink:NamedThing	plastid intermembrane space	The region between the inner and outer lipid bilayers of the plastid envelope.	tmpzr1t_l9r_go_relaxed.owl	plastid envelope lumen													cellular_component											owl:Class	
GO:0043416	biolink:NamedThing	regulation of skeletal muscle tissue regeneration	Any process that modulates the frequency, rate or extent of skeletal muscle.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0001639	biolink:NamedThing	PLC activating G protein-coupled glutamate receptor activity	A G protein-coupled receptor that binds glutamate and is linked to the inositol 1,4,5-trisphosphate/calcium signaling system.	tmpzr1t_l9r_go_relaxed.owl	phospholipase C activating metabotropic glutamate receptor activity|group I metabotropic glutamate receptor activity|Group I metabotropic glutamate receptor|PLC activating G-protein coupled glutamate receptor activity|PLC activating metabotropic glutamate receptor activity													molecular_function											owl:Class	
GO:0098988	biolink:NamedThing	G protein-coupled glutamate receptor activity	Combining with glutamate and transmitting a signal from one side of the membrane to the other by activating an associated G-protein, initiating a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	G-protein coupled glutamate receptor activity													molecular_function											owl:Class	
GO:0006392	biolink:NamedThing	transcription elongation from mitochondrial promoter	The extension of an RNA molecule after transcription initiation and promoter clearance at mitochondrial promoter by the addition of ribonucleotides catalyzed by a mitchondrial RNA polymerase.	tmpzr1t_l9r_go_relaxed.owl	RNA elongation from mitochondrial promoter													biological_process											owl:Class	
GO:0006354	biolink:NamedThing	DNA-templated transcription, elongation	The extension of an RNA molecule after transcription initiation and promoter clearance at a DNA-dependent RNA polymerase promoter by the addition of ribonucleotides catalyzed by an RNA polymerase.	tmpzr1t_l9r_go_relaxed.owl	RNA elongation|transcription elongation from bacterial-type RNA polymerase promoter|transcriptional elongation, DNA-dependent|DNA-dependent transcription, elongation|transcription elongation, DNA-dependent|RNA elongation from bacterial-type RNA polymerase promoter											GO:0001124		biological_process											owl:Class	
GO:1903630	biolink:NamedThing	regulation of aminoacyl-tRNA ligase activity	Any process that modulates the frequency, rate or extent of aminoacyl-tRNA ligase activity.	tmpzr1t_l9r_go_relaxed.owl	regulation of aminoacyl-tRNA synthetase activity|regulation of aminoacyl-tRNA synthetase auxiliary protein activity							sl	2014-11-20T00:22:04Z					biological_process											owl:Class	
GO:1904025	biolink:NamedThing	positive regulation of glucose catabolic process to lactate via pyruvate	Any process that activates or increases the frequency, rate or extent of glucose catabolic process to lactate via pyruvate.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of homofermentative lactate fermentation|up-regulation of homolactic fermentation|upregulation of homolactate fermentation|positive regulation of homofermentation|upregulation of homofermentative pathway|up regulation of homofermentative pathway|up regulation of glucose fermentation to lactate via pyruvate|up regulation of homolactate fermentation|activation of glucose catabolic process to lactate via pyruvate|up-regulation of glucose catabolic process to lactate via pyruvate|upregulation of homolactic fermentation|activation of homolactic fermentation|positive regulation of homolactate fermentation|up regulation of homofermentative lactate fermentation|activation of homofermentation|up-regulation of glucose fermentation to lactate via pyruvate|activation of glucose fermentation to lactate via pyruvate|up-regulation of homofermentative pathway|up-regulation of homofermentation|up-regulation of homolactate fermentation|up regulation of homolactic fermentation|upregulation of homofermentation|positive regulation of homolactic fermentation|positive regulation of homofermentative pathway|up regulation of glucose catabolic process to lactate via pyruvate|upregulation of homofermentative lactate fermentation|upregulation of glucose catabolic process to lactate via pyruvate|upregulation of glucose fermentation to lactate via pyruvate|positive regulation of homofermentative lactate fermentation|activation of homofermentative pathway|positive regulation of glucose fermentation to lactate via pyruvate|activation of homofermentative lactate fermentation|activation of homolactate fermentation|up regulation of homofermentation							dph	2015-03-11T16:57:44Z					biological_process											owl:Class	
GO:0035666	biolink:NamedThing	TRIF-dependent toll-like receptor signaling pathway	Any series of molecular signals generated as a consequence of binding to a toll-like receptor where the TRIF adaptor mediates transduction of the signal. Toll-like receptors directly bind pattern motifs from a variety of microbial sources to initiate innate immune response.	tmpzr1t_l9r_go_relaxed.owl	TRIF-dependent TLR signaling pathway|TRIF-dependent toll-like receptor signalling pathway|Toll/IL-1 receptor (TIR) domain-containing adaptor-dependent TLR signaling pathway							bf	2011-02-01T02:35:35Z					biological_process											owl:Class	
GO:0002756	biolink:NamedThing	MyD88-independent toll-like receptor signaling pathway	Any series of molecular signals generated as a consequence of binding to a toll-like receptor not relying on the MyD88 adaptor molecule. Toll-like receptors directly bind pattern motifs from a variety of microbial sources to initiate innate immune response.	tmpzr1t_l9r_go_relaxed.owl	MyD88-independent toll-like receptor signalling pathway|MyD88-independent TLR signaling pathway													biological_process											owl:Class	
GO:0051607	biolink:NamedThing	defense response to virus	Reactions triggered in response to the presence of a virus that act to protect the cell or organism.	tmpzr1t_l9r_go_relaxed.owl	defence response to virus|antiviral response|defense response to viruses													biological_process											owl:Class	
GO:0009615	biolink:NamedThing	response to virus	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a virus.	tmpzr1t_l9r_go_relaxed.owl	response to viruses													biological_process											owl:Class	
GO:0032829	biolink:NamedThing	regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation	Any process that modulates the frequency, rate or extent of differentiation of CD4-positive, CD25-positive, alpha-beta regulatory T cells.	tmpzr1t_l9r_go_relaxed.owl	regulation of CD4-positive, CD25-positive, alpha-beta regulatory T-cell differentiation|regulation of CD4-positive, CD25-positive, alpha-beta regulatory T lymphocyte differentiation|regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell development|regulation of CD4-positive, CD25-positive, alpha-beta regulatory T-lymphocyte differentiation					Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.								biological_process											owl:Class	
GO:0043370	biolink:NamedThing	regulation of CD4-positive, alpha-beta T cell differentiation	Any process that modulates the frequency, rate, or extent of CD4-positive, alpha-beta T cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	regulation of CD4-positive T-lymphocyte differentiation|regulation of CD4-positive T lymphocyte differentiation|regulation of CD4-positive, alpha beta T cell differentiation|regulation of CD4-positive, alpha beta T-lymphocyte differentiation|regulation of CD4-positive, alpha beta T cell development|regulation of CD4-positive, alpha beta T lymphocyte differentiation|regulation of CD4-positive T-cell differentiation|regulation of CD4-positive, alpha beta T-cell differentiation					Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.								biological_process											owl:Class	
GO:0090251	biolink:NamedThing	protein localization involved in establishment of planar polarity	Any process in which a protein is transported to, and/or maintained in, a specific location in a cell that contributes to the establishment of planar polarity.	tmpzr1t_l9r_go_relaxed.owl	protein localisation involved in establishment of planar polarity							tb	2010-01-22T11:31:32Z					biological_process											owl:Class	
GO:0120236	biolink:NamedThing	negative regulation of posttranslational protein targeting to membrane, translocation	Any process that stops, prevents or reduces the frequency, rate or extent of posttranslational protein translocation through the ER membrane.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of N-terminal signal peptide-independent translocation into the ER|negative regulation of posttranslational endoplasmic reticulum membrane protein translocation|negative regulation of SRP-independent endoplasmic reticulum protein-membrane targeting, translocation	https://github.com/geneontology/go-ontology/issues/19791						krc	2020-08-03T17:12:53Z					biological_process											owl:Class	
GO:0034763	biolink:NamedThing	negative regulation of transmembrane transport	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a solute from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of membrane transport|down regulation of transmembrane transport|down-regulation of transmembrane transport|downregulation of transmembrane transport|inhibition of transmembrane transport													biological_process											owl:Class	
GO:0043556	biolink:NamedThing	regulation of translation in response to oxidative stress	Any process that modulates the frequency, rate or extent of translation as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0032055	biolink:NamedThing	negative regulation of translation in response to stress	Any process that stops, prevents or reduces the rate of translation as a result of a stimulus indicating the organism is under stress.	tmpzr1t_l9r_go_relaxed.owl	down regulation of translation in response to stress|inhibition of translation in response to stress|down-regulation of translation in response to stress|downregulation of translation in response to stress													biological_process											owl:Class	
GO:1903591	biolink:NamedThing	negative regulation of lysozyme activity	Any process that stops, prevents or reduces the frequency, rate or extent of lysozyme activity.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of L-7001|downregulation of L-7001|negative regulation of lysozyme g|down-regulation of 1,4-N-acetylmuramidase activity|downregulation of muramidase activity|down-regulation of mucopeptide N-acetylmuramoylhydrolase activity|down-regulation of lysozyme activity|down regulation of peptidoglycan N-acetylmuramoylhydrolase activity|down regulation of PR1-lysozyme|down-regulation of mucopeptide glucohydrolase activity|downregulation of mucopeptide N-acetylmuramoylhydrolase activity|negative regulation of muramidase activity|inhibition of peptidoglycan N-acetylmuramoylhydrolase activity|downregulation of 1,4-N-acetylmuramidase activity|negative regulation of globulin G1|down regulation of mucopeptide glucohydrolase activity|inhibition of PR1-lysozyme|inhibition of muramidase activity|downregulation of lysozyme g|down-regulation of peptidoglycan N-acetylmuramoylhydrolase activity|down regulation of muramidase activity|inhibition of globulin G|negative regulation of mucopeptide glucohydrolase activity|downregulation of N,O-diacetylmuramidase activity|down regulation of N,O-diacetylmuramidase activity|downregulation of globulin G1|down-regulation of globulin G1|negative regulation of globulin G|inhibition of N,O-diacetylmuramidase activity|inhibition of mucopeptide N-acetylmuramoylhydrolase activity|downregulation of peptidoglycan N-acetylmuramoylhydrolase activity|inhibition of mucopeptide glucohydrolase activity|inhibition of globulin G1|downregulation of lysozyme activity|inhibition of lysozyme g|negative regulation of mucopeptide N-acetylmuramoylhydrolase activity|down regulation of globulin G|down regulation of L-7001|inhibition of 1,4-N-acetylmuramidase activity|down-regulation of muramidase activity|inhibition of L-7001|down regulation of globulin G1|negative regulation of PR1-lysozyme|down regulation of lysozyme g|down-regulation of globulin G|negative regulation of N,O-diacetylmuramidase activity|downregulation of globulin G|down regulation of 1,4-N-acetylmuramidase activity|down-regulation of L-7001|down regulation of mucopeptide N-acetylmuramoylhydrolase activity|downregulation of mucopeptide glucohydrolase activity|inhibition of lysozyme activity|down-regulation of lysozyme g|down-regulation of N,O-diacetylmuramidase activity|negative regulation of 1,4-N-acetylmuramidase activity|downregulation of PR1-lysozyme|down regulation of lysozyme activity|down-regulation of PR1-lysozyme|negative regulation of peptidoglycan N-acetylmuramoylhydrolase activity							mr	2014-11-05T21:41:30Z					biological_process											owl:Class	
GO:0051346	biolink:NamedThing	negative regulation of hydrolase activity	Any process that stops or reduces the rate of hydrolase activity, the catalysis of the hydrolysis of various bonds.	tmpzr1t_l9r_go_relaxed.owl	down regulation of hydrolase activity|hydrolase inhibitor|downregulation of hydrolase activity|inhibition of hydrolase activity|down-regulation of hydrolase activity													biological_process											owl:Class	
GO:1903397	biolink:NamedThing	positive regulation of secondary cell septum biogenesis	Any process that activates or increases the frequency, rate or extent of secondary cell septum biogenesis.	tmpzr1t_l9r_go_relaxed.owl	up regulation of secondary cell septum biogenesis|activation of secondary cell septum biogenesis|upregulation of secondary cell septum biogenesis|up-regulation of secondary cell septum biogenesis							di	2014-08-29T21:42:34Z					biological_process											owl:Class	
GO:0140281	biolink:NamedThing	positive regulation of mitotic division septum assembly	Any process that activates or increases the frequency, rate or extent of mitotic division septum formation. Division septum formation is the assembly and arrangement of a septum that spans the plasma membrane interface between progeny cells following cytokinesis.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of septin assembly and septum biosynthesis involved in mitotic cell cycle|activation of septin assembly and septum formation involved in mitotic cell cycle|upregulation of septin assembly and septum formation involved in mitotic cell cycle|activation of mitotic division septum assembly|up-regulation of division septum formation involved in mitotic cell cycle|up regulation of septin assembly and septum biosynthesis involved in mitotic cell cycle|up regulation of septin assembly and septum formation involved in mitotic cell cycle|activation of formation of division septum involved in mitotic cell cycle|positive regulation of formation of division septum involved in mitotic cell cycle|up-regulation of septin assembly and septum formation involved in mitotic cell cycle|upregulation of septin assembly and septum biosynthesis involved in mitotic cell cycle|positive regulation of division septum formation involved in mitotic cell cycle|upregulation of formation of division septum involved in mitotic cell cycle|activation of division septum formation involved in mitotic cell cycle|upregulation of division septum formation involved in mitotic cell cycle|up-regulation of mitotic division septum assembly|up regulation of mitotic division septum assembly|up regulation of division septum formation involved in mitotic cell cycle|activation of septin assembly and septum biosynthesis involved in mitotic cell cycle|up-regulation of septin assembly and septum biosynthesis involved in mitotic cell cycle|up-regulation of formation of division septum involved in mitotic cell cycle|positive regulation of septin assembly and septum formation involved in mitotic cell cycle|up regulation of formation of division septum involved in mitotic cell cycle							pg	2018-10-08T10:03:30Z					biological_process											owl:Class	
GO:0032704	biolink:NamedThing	negative regulation of interleukin-20 production	Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-20 production.	tmpzr1t_l9r_go_relaxed.owl	down regulation of interleukin-20 production|negative regulation of interleukin-20 biosynthetic process|down-regulation of interleukin-20 production|inhibition of interleukin-20 production|downregulation of interleukin-20 production|negative regulation of IL-20 production											GO:0045388		biological_process											owl:Class	
GO:0003314	biolink:NamedThing	heart rudiment morphogenesis	The process in which the anatomical structures of the heart rudiment are generated and organized.	tmpzr1t_l9r_go_relaxed.owl	heart cone morphogenesis							dph	2009-10-27T08:38:04Z					biological_process											owl:Class	
GO:0002009	biolink:NamedThing	morphogenesis of an epithelium	The process in which the anatomical structures of epithelia are generated and organized. An epithelium consists of closely packed cells arranged in one or more layers, that covers the outer surfaces of the body or lines any internal cavity or tube.	tmpzr1t_l9r_go_relaxed.owl	epithelium morphogenesis													biological_process											owl:Class	
GO:0010127	biolink:NamedThing	mycothiol-dependent detoxification	The chemical reactions using mycothiol to convert an alkylating agent to an S-conjugate of mycothiol. The latter is cleaved to release mercapturic acid which is excreted from the cell.	tmpzr1t_l9r_go_relaxed.owl	mycothiol-dependent detoxification of alkylating agent				MetaCyc:PWY1G-170|MetaCyc:PWY1G-1									biological_process											owl:Class	
GO:0098754	biolink:NamedThing	detoxification	Any process that reduces or removes the toxicity of a toxic substance. These may include transport of the toxic substance away from sensitive areas and to compartments or complexes whose purpose is sequestration of the toxic substance.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0002659	biolink:NamedThing	negative regulation of peripheral tolerance induction	Any process that stops, prevents, or reduces the frequency, rate, or extent of peripheral tolerance induction.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of peripheral tolerance induction|downregulation of peripheral tolerance induction|down regulation of peripheral tolerance induction|inhibition of peripheral tolerance induction													biological_process											owl:Class	
GO:0002653	biolink:NamedThing	negative regulation of tolerance induction dependent upon immune response	Any process that stops, prevents, or reduces the frequency, rate, or extent of tolerance induction dependent upon immune response.	tmpzr1t_l9r_go_relaxed.owl	inhibition of tolerance induction dependent upon immune response|negative regulation of immune response-dependent tolerance induction|down-regulation of tolerance induction dependent upon immune response|downregulation of tolerance induction dependent upon immune response|down regulation of tolerance induction dependent upon immune response													biological_process											owl:Class	
GO:0003198	biolink:NamedThing	epithelial to mesenchymal transition involved in endocardial cushion formation	A transition where a cardiac epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell that will contribute to the formation of the endocardial cushion.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-10-08T01:27:42Z					biological_process											owl:Class	
GO:0060317	biolink:NamedThing	cardiac epithelial to mesenchymal transition	A transition where a cardiac epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell.	tmpzr1t_l9r_go_relaxed.owl	heart epithelial to mesenchymal transition													biological_process											owl:Class	
GO:0031463	biolink:NamedThing	Cul3-RING ubiquitin ligase complex	A ubiquitin ligase complex in which a cullin from the Cul3 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by a BTB-domain-containing protein.	tmpzr1t_l9r_go_relaxed.owl	CRL3 complex|cullin-RING ligase 3|SCF3 complex|BCR3 complex|CDL3 complex|BC3B complex													cellular_component											owl:Class	
GO:0031461	biolink:NamedThing	cullin-RING ubiquitin ligase complex	Any ubiquitin ligase complex in which the catalytic core consists of a member of the cullin family and a RING domain protein; the core is associated with one or more additional proteins that confer substrate specificity.	tmpzr1t_l9r_go_relaxed.owl	cullin-RING ligase|CRL complex|cullin complex													cellular_component											owl:Class	
GO:1901820	biolink:NamedThing	alpha-zeacarotene catabolic process	The chemical reactions and pathways resulting in the breakdown of alpha-zeacarotene.	tmpzr1t_l9r_go_relaxed.owl	alpha-zeacarotene catabolism|alpha-zeacarotene breakdown|alpha-zeacarotene degradation							yaf	2013-01-22T10:51:06Z					biological_process											owl:Class	
GO:1900049	biolink:NamedThing	regulation of histone exchange	Any process that modulates the frequency, rate or extent of histone exchange.	tmpzr1t_l9r_go_relaxed.owl	regulation of histone chaperone|regulation of histone replacement|regulation of histone displacement							se	2012-01-19T10:59:02Z					biological_process											owl:Class	
GO:0021833	biolink:NamedThing	cell-matrix adhesion involved in tangential migration using cell-cell interactions	The interaction of a cell and the extracellular matrix involved in the directed tangential movement of cells mediated by cell-cell interactions in the developing cerebral cortex.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0003430	biolink:NamedThing	growth plate cartilage chondrocyte growth	The growth of a growth plate cartilage chondrocyte, where growth contributes to the progression of the chondrocyte over time from one condition to another.	tmpzr1t_l9r_go_relaxed.owl	growth plate cartilage chondrocyte hypertrophy							dph	2009-12-22T12:29:19Z					biological_process											owl:Class	
GO:0060560	biolink:NamedThing	developmental growth involved in morphogenesis	The increase in size or mass of an anatomical structure that contributes to the structure attaining its shape.	tmpzr1t_l9r_go_relaxed.owl	differential growth							dph	2009-04-28T08:42:53Z					biological_process											owl:Class	
GO:0045311	biolink:NamedThing	invasive growth in response to pheromone	The growth of colonies in filamentous chains of cells as a result of a pheromone stimulus.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0036267	biolink:NamedThing	invasive filamentous growth	The growth of colonies in filamentous chains of cells into a substrate.	tmpzr1t_l9r_go_relaxed.owl	invasive growth							bf	2012-07-02T01:42:24Z					biological_process											owl:Class	
GO:0018642	biolink:NamedThing	chlorophenol 4-monooxygenase activity	Catalysis of the addition or substitution of an OH group on C4 of a halogenated phenol.	tmpzr1t_l9r_go_relaxed.owl					EC:1.14.13.-|UM-BBD_enzymeID:e0252									molecular_function											owl:Class	
GO:0090585	biolink:NamedThing	protein-phosphocysteine-L-ascorbate-phosphotransferase system transporter activity	Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein S-phosphocysteine + L-ascorbate(out) = protein cysteine + L-ascorbate-6-phosphate(in).	tmpzr1t_l9r_go_relaxed.owl								tb	2014-06-04T16:22:31Z					molecular_function											owl:Class	
GO:0090563	biolink:NamedThing	protein-phosphocysteine-sugar phosphotransferase activity	Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein S-phosphocysteine + sugar(out) = protein cysteine + sugar phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.	tmpzr1t_l9r_go_relaxed.owl								tb	2014-04-08T14:58:00Z					molecular_function											owl:Class	
GO:0003226	biolink:NamedThing	right ventricular compact myocardium morphogenesis	The process in which the anatomical structures of the right ventricular compact myocardium are generated and organized.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-10-13T10:48:42Z					biological_process											owl:Class	
GO:0003223	biolink:NamedThing	ventricular compact myocardium morphogenesis	The process in which the anatomical structures of the compact cardiac ventricle muscle are generated and organized.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-10-13T10:34:21Z					biological_process											owl:Class	
GO:0047677	biolink:NamedThing	arachidonate 8(R)-lipoxygenase activity	Catalysis of the reaction: arachidonate + O(2) = (5Z,8R,9E,11Z,14Z)-8-hydroperoxyicosa-5,9,11,14-tetraenoate.	tmpzr1t_l9r_go_relaxed.owl	8(R)-lipoxygenase activity|arachidonate 8-lipoxygenase activity|8-lipoxygenase activity|arachidonate:oxygen 8-oxidoreductase activity				RHEA:14985|EC:1.13.11.40|MetaCyc:ARACHIDONATE-8-LIPOXYGENASE-RXN|KEGG_REACTION:R01594	This activity produces the R-enantiomer of HPETE, 8(R)-HPETE. For the reaction producing the S-enantiomer, see GO:0036403.								molecular_function											owl:Class	
GO:0008829	biolink:NamedThing	dCTP deaminase activity	Catalysis of the reaction: dCTP + H2O = dUTP + NH3.	tmpzr1t_l9r_go_relaxed.owl	dCTP aminohydrolase activity|5-methyl-dCTP deaminase activity|deoxycytidine triphosphate deaminase activity				RHEA:22680|MetaCyc:DCTP-DEAM-RXN|Reactome:R-HSA-180632|EC:3.5.4.13									molecular_function											owl:Class	
GO:0048476	biolink:NamedThing	Holliday junction resolvase complex	An endodeoxyribonuclease complex that resolves the 4-way DNA intermediates of a Holliday junction into two separate duplex DNA molecules. Can be branch-migration associated.	tmpzr1t_l9r_go_relaxed.owl	Mus81-Eme1 complex|Mus81-Eme2 holliday resolvase complex|Mus81-Eme1 holliday resolvase complex|Mus81-Eme2 complex|resolvasome													cellular_component											owl:Class	
GO:1905347	biolink:NamedThing	endodeoxyribonuclease complex	A protein complex which is capable of endodeoxyribonuclease activity.	tmpzr1t_l9r_go_relaxed.owl	Mus81-Eme1 complex|Mus81-Eme2 complex					An example of this is MUS81 in human (Q96NY9) in PMID:18413719 (inferred from direct assay).		bhm	2016-08-03T12:20:12Z					cellular_component											owl:Class	
GO:0060956	biolink:NamedThing	endocardial cell differentiation	The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of an endocardial cell. An endocardial cell is a specialized endothelial cell that makes up the endocardium portion of the heart. The endocardium is the innermost layer of tissue of the heart, and lines the heart chambers.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-09-29T03:20:39Z					biological_process											owl:Class	
GO:1905737	biolink:NamedThing	positive regulation of L-proline import across plasma membrane	Any process that activates or increases the frequency, rate or extent of L-proline import across plasma membrane.	tmpzr1t_l9r_go_relaxed.owl								vw	2016-12-04T20:42:33Z					biological_process											owl:Class	
GO:1902836	biolink:NamedThing	positive regulation of proline import across plasma membrane	Any process that activates or increases the frequency, rate or extent of proline import into cell.	tmpzr1t_l9r_go_relaxed.owl	activation of proline import into cell|up-regulation of proline import into cell|up regulation of proline import into cell|positive regulation of proline import into cell|upregulation of proline import into cell							mah	2014-04-01T13:44:20Z					biological_process											owl:Class	
GO:0045521	biolink:NamedThing	interleukin-25 receptor binding	Binding to an interleukin-25 receptor.	tmpzr1t_l9r_go_relaxed.owl	interleukin-25 receptor ligand|IL-25													molecular_function											owl:Class	
GO:0005126	biolink:NamedThing	cytokine receptor binding	Binding to a cytokine receptor.	tmpzr1t_l9r_go_relaxed.owl	hematopoietin/interferon-class (D200-domain) cytokine receptor binding|hematopoietin/interferon-class (D200-domain) cytokine receptor ligand													molecular_function											owl:Class	
GO:2000205	biolink:NamedThing	positive regulation of ribosomal large subunit export from nucleus	Any process that activates or increases the frequency, rate or extent of ribosomal large subunit export from nucleus.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of 60S ribosomal subunit export from nucleus|positive regulation of ribosomal large subunit export from cell nucleus|positive regulation of ribosomal large subunit transport from nucleus to cytoplasm|positive regulation of ribosomal large subunit export out of nucleus|positive regulation of 50S ribosomal subunit export from nucleus|positive regulation of ribosomal large subunit-nucleus export							mah	2010-10-26T10:52:42Z					biological_process											owl:Class	
GO:2000202	biolink:NamedThing	positive regulation of ribosomal subunit export from nucleus	Any process that activates or increases the frequency, rate or extent of ribosomal subunit export from nucleus.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of ribosomal subunit export out of nucleus|positive regulation of ribosomal subunit transport from nucleus to cytoplasm|positive regulation of ribosome export from nucleus|positive regulation of ribosomal subunit export from cell nucleus|positive regulation of ribosomal subunit-nucleus export							mah	2010-10-26T10:44:36Z					biological_process											owl:Class	
GO:1990545	biolink:NamedThing	mitochondrial thiamine pyrophosphate transmembrane transport	The process in which thiamine pyrophosphate is transported across a mitochondrial membrane, into or out of the mitochondrion.	tmpzr1t_l9r_go_relaxed.owl								vw	2014-11-19T11:47:15Z					biological_process											owl:Class	
GO:0030974	biolink:NamedThing	thiamine pyrophosphate transmembrane transport	The process in which thiamine pyrophosphate is transported across a membrane.	tmpzr1t_l9r_go_relaxed.owl	thiamine pyrophosphate transport|thiamin diphosphate transport|thiamin pyrophosphate transport|thiamine diphosphate transport|TPP transport													biological_process											owl:Class	
GO:0031494	biolink:NamedThing	regulation of mating type switching	Any process that modulates the frequency, rate or extent of mating type switching, the conversion of a single-cell organism from one mating type to another by the precise replacement of a DNA sequence at the expressed mating type locus with a copy of a sequence from a donor locus.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0030143	biolink:NamedThing	COPI-coated inter-Golgi transport vesicle	A vesicle that mediates transport of cargo within the Golgi complex (for example, between cisternae of the Golgi stack).	tmpzr1t_l9r_go_relaxed.owl	inter-Golgi transport constitutive secretory pathway transport vesicle				NIF_Subcellular:sao1382918459							GO:0005807		cellular_component											owl:Class	
GO:0030133	biolink:NamedThing	transport vesicle	Any of the vesicles of the constitutive secretory pathway, which carry cargo from the endoplasmic reticulum to the Golgi, between Golgi cisternae, from the Golgi to the ER (retrograde transport) or to destinations within or outside the cell.	tmpzr1t_l9r_go_relaxed.owl	Golgi-vacuole transport vesicle|constitutive secretory pathway transport vesicle|Golgi to vacuole transport vesicle|secretory vesicle				NIF_Subcellular:sao885490876	Note that the term 'secretory vesicle' is sometimes used in this sense, but can also mean 'secretory granule ; GO:0030141'.								cellular_component											owl:Class	
GO:0090487	biolink:NamedThing	secondary metabolite catabolic process	The chemical reactions and pathways resulting in the breakdown of secondary metabolites, the compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon.	tmpzr1t_l9r_go_relaxed.owl	secondary metabolite breakdown|secondary metabolite catabolism|secondary metabolite degradation							tb	2012-10-15T16:43:09Z					biological_process											owl:Class	
GO:1905843	biolink:NamedThing	regulation of cellular response to gamma radiation	Any process that modulates the frequency, rate or extent of cellular response to gamma radiation.	tmpzr1t_l9r_go_relaxed.owl	regulation of cellular response to gamma ray|regulation of cellular response to gamma-ray photon							rz	2017-01-19T10:24:39Z					biological_process											owl:Class	
GO:1990928	biolink:NamedThing	response to amino acid starvation	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of amino acids.	tmpzr1t_l9r_go_relaxed.owl								sl	2016-02-18T00:18:23Z					biological_process											owl:Class	
GO:0022835	biolink:NamedThing	transmitter-gated channel activity	Enables the transmembrane transfer of a solute by a channel that opens when a specific neurotransmitter has been bound by the channel complex or one of its constituent parts.	tmpzr1t_l9r_go_relaxed.owl	extracellular substance gated channel activity|neurotransmitter-gated channel activity													molecular_function											owl:Class	
GO:0051160	biolink:NamedThing	L-xylitol catabolic process	The chemical reactions and pathways resulting in the breakdown of L-xylitol, a five-carbon sugar alcohol derived from xylose by reduction of the carbonyl group.	tmpzr1t_l9r_go_relaxed.owl	L-xylitol breakdown|L-xylitol degradation|L-xylitol catabolism													biological_process											owl:Class	
GO:0035082	biolink:NamedThing	axoneme assembly	The assembly and organization of an axoneme, the bundle of microtubules and associated proteins that forms the core of cilia (also called flagella) in eukaryotic cells and is responsible for their movements.	tmpzr1t_l9r_go_relaxed.owl	flagellar axoneme assembly|axoneme biogenesis|ciliary axoneme assembly|cilium axoneme biogenesis|flagellum axoneme assembly|cilium axoneme assembly					Note that cilia and eukaryotic flagella are deemed to be equivalent.						GO:0035084|GO:0035083		biological_process											owl:Class	
GO:0050428	biolink:NamedThing	3'-phosphoadenosine 5'-phosphosulfate biosynthetic process	The chemical reactions and pathways resulting in the formation of 3'-phosphoadenosine 5'-phosphosulfate, a naturally occurring mixed anhydride. It is an intermediate in the formation of a variety of sulfo compounds in biological systems.	tmpzr1t_l9r_go_relaxed.owl	adenosine 3'-phosphate 5'-phosphosulfate biosynthetic process|phosphoadenosine phosphosulfate biosynthetic process|3'-phosphoadenylyl-sulfate biosynthetic process|3'-phosphoadenosine 5'-phosphosulphate biosynthesis|3'-phosphoadenosine 5'-phosphosulfate synthesis|3'-phosphoadenosine 5'-phosphosulfate formation|3'-phosphoadenosine 5'-phosphosulfate biosynthesis|3'-phosphoadenosine 5'-phosphosulfate anabolism|PAPS biosynthesis|3'-phosphoadenosine 5'-phosphosulphate biosynthetic process|adenosine 3'-phosphate 5'-phosphosulfate biosynthesis|phosphoadenosine phosphosulfate biosynthesis|3'-phosphoadenylyl-sulfate biosynthesis|PAPS biosynthetic process													biological_process											owl:Class	
GO:1905766	biolink:NamedThing	positive regulation of protection from non-homologous end joining at telomere	Any process that activates or increases the frequency, rate or extent of protection from non-homologous end joining at telomere.	tmpzr1t_l9r_go_relaxed.owl	upregulation of protection from non-homologous end joining at telomere|up-regulation of protection from NHEJ-mediated telomere fusion|upregulation of protection from NHEJ-mediated telomere fusion|positive regulation of protection from NHEJ-mediated telomere fusion|up regulation of protection from NHEJ-mediated telomere fusion|activation of protection from NHEJ-mediated telomere fusion|activation of protection from non-homologous end joining at telomere|up-regulation of protection from non-homologous end joining at telomere|up regulation of protection from non-homologous end joining at telomere							nc	2016-12-20T11:28:39Z					biological_process											owl:Class	
GO:0033873	biolink:NamedThing	petromyzonol sulfotransferase activity	Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + 5alpha-cholane-3alpha,7alpha,12alpha,24-tetrol = 3alpha,7alpha,12alpha-trihydroxy-5alpha-cholan-24-yl sulfate + adenosine 3',5'-diphosphate + H(+).	tmpzr1t_l9r_go_relaxed.owl	3'-phosphoadenylyl-sulfate:5alpha-cholan-3alpha,7alpha,12alpha,24-tetrol sulfotransferase activity|PZ-SULT				KEGG_REACTION:R07797|MetaCyc:2.8.2.31-RXN|RHEA:16997|EC:2.8.2.31									molecular_function											owl:Class	
GO:0035929	biolink:NamedThing	steroid hormone secretion	The regulated release of any steroid that acts as a hormone into the circulatory system.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-07-20T01:01:00Z					biological_process											owl:Class	
GO:0140353	biolink:NamedThing	lipid export from cell	The directed movement of a lipid from a cell, into the extracellular region.	tmpzr1t_l9r_go_relaxed.owl	lipid efflux							pg	2019-05-22T11:33:07Z					biological_process											owl:Class	
GO:1903055	biolink:NamedThing	positive regulation of extracellular matrix organization	Any process that activates or increases the frequency, rate or extent of extracellular matrix organization.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of extracellular matrix organization and biogenesis|up-regulation of extracellular matrix organisation|activation of extracellular matrix organization|up regulation of extracellular matrix organization and biogenesis|upregulation of extracellular matrix organisation|positive regulation of extracellular matrix organisation|up regulation of extracellular matrix organisation|upregulation of extracellular matrix organization|upregulation of extracellular matrix organization and biogenesis|up-regulation of extracellular matrix organization|activation of extracellular matrix organisation|activation of extracellular matrix organization and biogenesis|up-regulation of extracellular matrix organization and biogenesis|up regulation of extracellular matrix organization							rl	2014-05-23T17:15:53Z					biological_process											owl:Class	
GO:0051130	biolink:NamedThing	positive regulation of cellular component organization	Any process that activates or increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of cell organization|up regulation of cell organization|positive regulation of cellular component organization and biogenesis|upregulation of cell organization|activation of cell organization|positive regulation of cell organisation|stimulation of cell organization													biological_process											owl:Class	
GO:1905505	biolink:NamedThing	positive regulation of motile cilium assembly	Any process that activates or increases the frequency, rate or extent of motile cilium assembly.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of nodal cilium formation|activation of nodal cilium assembly|up regulation of motile primary cilia assembly|upregulation of nodal cilium assembly|up-regulation of motile primary cilia formation|up-regulation of motile primary cilia assembly|activation of motile primary cilium formation|up-regulation of motile primary cilium assembly|up-regulation of nodal cilium assembly|upregulation of motile primary cilia formation|positive regulation of nodal cilium formation|up regulation of motile primary cilia formation|activation of motile primary cilia assembly|up regulation of nodal cilium assembly|positive regulation of nodal cilium assembly|upregulation of nodal cilium formation|up-regulation of motile primary cilium formation|activation of motile primary cilium assembly|up regulation of motile primary cilium assembly|activation of nodal cilium formation|positive regulation of motile primary cilium formation|positive regulation of motile primary cilia formation|activation of motile primary cilia formation|positive regulation of motile primary cilia assembly|up regulation of motile primary cilium formation|upregulation of motile primary cilium formation|upregulation of motile primary cilium assembly|up regulation of nodal cilium formation|upregulation of motile primary cilia assembly|positive regulation of motile primary cilium assembly							krc	2016-09-27T18:28:03Z					biological_process											owl:Class	
GO:0006616	biolink:NamedThing	SRP-dependent cotranslational protein targeting to membrane, translocation	The process during cotranslational membrane targeting wherein proteins move across a membrane. SRP and its receptor initiate the transfer of the nascent chain across the endoplasmic reticulum (ER) membrane; they then dissociate from the chain, which is transferred to a set of transmembrane proteins, collectively called the translocon. Once the nascent chain translocon complex is assembled, the elongating chain passes directly from the large ribosomal subunit into the centers of the translocon, a protein-lined channel within the membrane. The growing chain is never exposed to the cytosol and does not fold until it reaches the ER lumen.	tmpzr1t_l9r_go_relaxed.owl	SRP-dependent cotranslational protein-membrane targeting, translocation|SRP-dependent cotranslational membrane targeting, translocation|translocation during SRP-dependent cotranslational protein targeting to membrane|ER translocation													biological_process											owl:Class	
GO:0065002	biolink:NamedThing	intracellular protein transmembrane transport	The directed movement of proteins in a cell, from one side of a membrane to another by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	intracellular protein transport across a membrane|intracellular membrane translocation of a protein|intracellular protein membrane transport					Note that this term is not intended for use in annotating lateral movement within membranes.								biological_process											owl:Class	
GO:0097463	biolink:NamedThing	gemmule	Spine-like process found on some neurons, e.g., periglomerular cells of olfactory cortex.	tmpzr1t_l9r_go_relaxed.owl					NIF_Subcellular:nlx_subcell_1005003			pr	2012-12-21T07:59:04Z					cellular_component											owl:Class	
GO:0106011	biolink:NamedThing	regulation of protein localization to medial cortex	Any process that regulates the localization of a protein to the medial cortex.	tmpzr1t_l9r_go_relaxed.owl								hjd	2017-04-27T17:29:56Z					biological_process											owl:Class	
GO:0036289	biolink:NamedThing	peptidyl-serine autophosphorylation	The phosphorylation by a protein of one or more of its own serine amino acid residues, or a serine residue on an identical protein.	tmpzr1t_l9r_go_relaxed.owl	serine autophosphorylation							bf	2012-07-18T10:24:32Z					biological_process											owl:Class	
GO:0018105	biolink:NamedThing	peptidyl-serine phosphorylation	The phosphorylation of peptidyl-serine to form peptidyl-O-phospho-L-serine.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0037									biological_process											owl:Class	
GO:0031166	biolink:NamedThing	integral component of vacuolar membrane	The component of the vacuolar membrane consisting of gene products and protein complexes that have some part that penetrates at least one leaflet of the membrane bilayer. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer.	tmpzr1t_l9r_go_relaxed.owl	integral to vacuolar membrane													cellular_component											owl:Class	
GO:0031310	biolink:NamedThing	intrinsic component of vacuolar membrane	The component of the vacuolar membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.	tmpzr1t_l9r_go_relaxed.owl	intrinsic to vacuolar membrane													cellular_component											owl:Class	
GO:0048687	biolink:NamedThing	positive regulation of sprouting of injured axon	Any process that activates, maintains or increases the rate of sprouting of an injured axon.	tmpzr1t_l9r_go_relaxed.owl	up regulation of sprouting of injured axon|stimulation of sprouting of injured axon|up-regulation of sprouting of injured axon|upregulation of sprouting of injured axon|activation of sprouting of injured axon													biological_process											owl:Class	
GO:2000544	biolink:NamedThing	regulation of endothelial cell chemotaxis to fibroblast growth factor	Any process that modulates the frequency, rate or extent of endothelial cell chemotaxis to fibroblast growth factor.	tmpzr1t_l9r_go_relaxed.owl								ebc	2011-04-03T07:14:04Z					biological_process											owl:Class	
GO:0001116	biolink:NamedThing	protein-DNA-RNA complex assembly	The aggregation, arrangement and bonding together of proteins, DNA, and RNA molecules to form a protein-DNA-RNA complex.	tmpzr1t_l9r_go_relaxed.owl								krc	2010-12-03T04:01:38Z					biological_process											owl:Class	
GO:0009323	biolink:NamedThing	ribosomal-protein-alanine N-acetyltransferase complex	An enzyme complex that catalyzes the transfer of an acetyl group to ribosomal-protein alanine, forming ribosomal-protein acetylalanine.	tmpzr1t_l9r_go_relaxed.owl					EC:2.3.1.128									cellular_component											owl:Class	
GO:0031248	biolink:NamedThing	protein acetyltransferase complex	A complex that catalyzes the transfer of an acetyl group to a protein acceptor molecule.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0080168	biolink:NamedThing	abscisic acid transport	The directed movement of abscisic acid into, out of, within or between cells by means of some external agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl								dhl	2010-09-23T05:08:56Z					biological_process											owl:Class	
GO:0002689	biolink:NamedThing	negative regulation of leukocyte chemotaxis	Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte chemotaxis.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of immune cell chemotaxis|down regulation of leukocyte chemotaxis|downregulation of leukocyte chemotaxis|inhibition of leukocyte chemotaxis|negative regulation of leucocyte chemotaxis|down-regulation of leukocyte chemotaxis													biological_process											owl:Class	
GO:0046645	biolink:NamedThing	positive regulation of gamma-delta T cell activation	Any process that activates or increases the frequency, rate or extent of gamma-delta T cell activation.	tmpzr1t_l9r_go_relaxed.owl	up regulation of gamma-delta T cell activation|positive regulation of gamma-delta T-lymphocyte activation|up-regulation of gamma-delta T cell activation|activation of gamma-delta T cell activation|upregulation of gamma-delta T cell activation|positive regulation of gamma-delta T-cell activation|stimulation of gamma-delta T cell activation|positive regulation of gamma-delta T lymphocyte activation													biological_process											owl:Class	
GO:0048559	biolink:NamedThing	establishment of floral organ orientation	The process that determines the orientation of the floral organs with reference to the central axis of the flower.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0032655	biolink:NamedThing	regulation of interleukin-12 production	Any process that modulates the frequency, rate, or extent of interleukin-12 production.	tmpzr1t_l9r_go_relaxed.owl	regulation of NKSF production|regulation of interleukin-12 secretion|regulation of interleukin-12 biosynthetic process|regulation of IL-12 production|regulation of CLMF production											GO:0045075|GO:2001182		biological_process											owl:Class	
GO:0061631	biolink:NamedThing	ubiquitin conjugating enzyme activity	Isoenergetic transfer of ubiquitin from one protein to another via the reaction X-ubiquitin + Y -> Y-ubiquitin + X, where both the X-ubiquitin and Y-ubiquitin linkages are thioester bonds between the C-terminal glycine of ubiquitin and a sulfhydryl side group of a cysteine residue.	tmpzr1t_l9r_go_relaxed.owl	HECT E3|E2				EC:2.3.2.23			dph	2014-05-18T09:25:19Z					molecular_function											owl:Class	
GO:0004842	biolink:NamedThing	ubiquitin-protein transferase activity	Catalysis of the transfer of ubiquitin from one protein to another via the reaction X-Ub + Y --> Y-Ub + X, where both X-Ub and Y-Ub are covalent linkages.	tmpzr1t_l9r_go_relaxed.owl	ubiquitin ligase activity|ubiquitin protein-ligase activity|E3|ubiquitin-conjugating enzyme activity|ubiquitin conjugating enzyme activity|ubiquitin protein ligase activity|E2|anaphase-promoting complex activity				Reactome:R-HSA-1234172|Reactome:R-HSA-2187368|Reactome:R-HSA-5607728|Reactome:R-HSA-174159|Reactome:R-HSA-9013069|Reactome:R-HSA-1980074|Reactome:R-HSA-2900765|Reactome:R-HSA-183051|Reactome:R-HSA-1918095|Reactome:R-HSA-5607725|Reactome:R-HSA-5675470|Reactome:R-HSA-75824|Reactome:R-HSA-5357757|Reactome:R-HSA-174227|Reactome:R-HSA-400267|Reactome:R-HSA-183089|Reactome:R-HSA-168915|Reactome:R-HSA-201425|Reactome:R-HSA-174195|Reactome:R-HSA-1358789|Reactome:R-HSA-3788724|Reactome:R-HSA-870449|Reactome:R-HSA-1169405|Reactome:R-HSA-1169394|Reactome:R-HSA-1918092|Reactome:R-HSA-2213017|Reactome:R-HSA-5667111|Reactome:R-HSA-202453|Reactome:R-HSA-8956106|Reactome:R-HSA-8948709|Reactome:R-HSA-918224|Reactome:R-HSA-180597|Reactome:R-HSA-2169050|Reactome:R-HSA-2769007|Reactome:R-HSA-5607757|Reactome:R-HSA-3249386|Reactome:R-HSA-5660753|Reactome:R-HSA-3780995|Reactome:R-HSA-5684250|Reactome:R-HSA-1169398|Reactome:R-HSA-1169395|Reactome:R-HSA-209063|Reactome:R-HSA-983140|Reactome:R-HSA-9701000|Reactome:R-HSA-211734|Reactome:R-HSA-3134804|Reactome:R-HSA-2730904|Reactome:R-HSA-936986|Reactome:R-HSA-450358|Reactome:R-HSA-1358790|Reactome:R-HSA-1977296|Reactome:R-HSA-5655170|Reactome:R-HSA-5668454|Reactome:R-HSA-1253282|Reactome:R-HSA-5691108|Reactome:R-HSA-3134946|Reactome:R-HSA-182993|Reactome:R-HSA-180540|Reactome:R-HSA-182986|Reactome:R-HSA-5483238|Reactome:R-HSA-9688831|Reactome:R-HSA-187575|Reactome:R-HSA-446877|Reactome:R-HSA-983156|Reactome:R-HSA-1169402|Reactome:R-HSA-2172172|Reactome:R-HSA-2737728|Reactome:R-HSA-9628444|Reactome:R-HSA-5205682|Reactome:R-HSA-1912386|Reactome:R-HSA-173542|KEGG_REACTION:R03876|Reactome:R-HSA-2186747|Reactome:R-HSA-5610745|Reactome:R-HSA-4332236|Reactome:R-HSA-9014342|Reactome:R-HSA-1852623|Reactome:R-HSA-3781009|Reactome:R-HSA-5667107|Reactome:R-HSA-1234163|Reactome:R-HSA-5607756|Reactome:R-HSA-2179276|Reactome:R-HSA-179417|Reactome:R-HSA-2186785|Reactome:R-HSA-9013974|Reactome:R-HSA-202534|Reactome:R-HSA-174104|Reactome:R-HSA-936412|Reactome:R-HSA-264444|Reactome:R-HSA-69598|Reactome:R-HSA-975147|Reactome:R-HSA-983153|Reactome:R-HSA-3797226|Reactome:R-HSA-1363331|Reactome:R-HSA-5652009|Reactome:R-HSA-5693108|Reactome:R-HSA-741386|Reactome:R-HSA-174057|Reactome:R-HSA-3000335|Reactome:R-HSA-2682349|Reactome:R-HSA-5610746|Reactome:R-HSA-5362412|Reactome:R-HSA-174144|Reactome:R-HSA-9645414|Reactome:R-HSA-975118|Reactome:R-HSA-1980118|Reactome:R-HSA-9645394|Reactome:R-HSA-1912357|Reactome:R-HSA-5610742|Reactome:R-HSA-1358792|Reactome:R-HSA-1169397|Reactome:R-HSA-205118|Reactome:R-HSA-183084|Reactome:R-HSA-5668534|Reactome:R-HSA-451418|Reactome:R-HSA-1169406|Reactome:R-HSA-173545|Reactome:R-HSA-936942|Reactome:R-HSA-183036							GO:0004841|GO:0004840		molecular_function											owl:Class	
GO:0009000	biolink:NamedThing	selenocysteine lyase activity	Catalysis of the reaction: L-selenocysteine + reduced acceptor = hydrogen selenide + L-alanine + acceptor.	tmpzr1t_l9r_go_relaxed.owl	selenocysteine beta-lyase activity|L-selenocysteine selenide-lyase (L-alanine-forming)|selenocysteine reductase activity				MetaCyc:SELENOCYSTEINE-LYASE-RXN|Reactome:R-HSA-2408524|RHEA:11632|EC:4.4.1.16									molecular_function											owl:Class	
GO:0019803	biolink:NamedThing	peptidyl-aspartic acid carboxylation	The carboxylation of peptidyl-aspartic acid to form peptidyl-L-beta-carboxyaspartic acid.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0304									biological_process											owl:Class	
GO:0018214	biolink:NamedThing	protein carboxylation	The addition of a carboxy group to a protein amino acid.	tmpzr1t_l9r_go_relaxed.owl	protein amino acid carboxylation													biological_process											owl:Class	
GO:0032382	biolink:NamedThing	positive regulation of intracellular sterol transport	Any process that activates or increases the frequency, rate or extent of the directed movement of sterols within cells.	tmpzr1t_l9r_go_relaxed.owl	stimulation of intracellular sterol transport|upregulation of intracellular sterol transport|up-regulation of intracellular sterol transport|up regulation of intracellular sterol transport|activation of intracellular sterol transport													biological_process											owl:Class	
GO:0032380	biolink:NamedThing	regulation of intracellular sterol transport	Any process that modulates the frequency, rate or extent of the directed movement of sterols within cells.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0070964	biolink:NamedThing	positive regulation of neutrophil mediated killing of gram-positive bacterium	Any process that increases the frequency, rate or extent of the directed killing of a gram-positive bacterium by a neutrophil.	tmpzr1t_l9r_go_relaxed.owl	stimulation of neutrophil mediated killing of gram-positive bacterium|upregulation of neutrophil mediated killing of gram-positive bacterium|up-regulation of neutrophil mediated killing of gram-positive bacterium|activation of neutrophil mediated killing of gram-positive bacterium|up regulation of neutrophil mediated killing of gram-positive bacterium							mah	2009-10-01T02:28:49Z					biological_process											owl:Class	
GO:0070962	biolink:NamedThing	positive regulation of neutrophil mediated killing of bacterium	Any process that increases the frequency, rate or extent of the directed killing of a bacterium by a neutrophil.	tmpzr1t_l9r_go_relaxed.owl	upregulation of neutrophil mediated killing of bacterium|up-regulation of neutrophil mediated killing of bacterium|up regulation of neutrophil mediated killing of bacterium|stimulation of neutrophil mediated killing of bacterium|activation of neutrophil mediated killing of bacterium							mah	2009-10-01T02:28:49Z					biological_process											owl:Class	
GO:1901814	biolink:NamedThing	astaxanthin catabolic process	The chemical reactions and pathways resulting in the breakdown of astaxanthin.	tmpzr1t_l9r_go_relaxed.owl	astaxanthin degradation|astaxanthin catabolism|astaxanthin breakdown							yaf	2013-01-22T10:37:03Z					biological_process											owl:Class	
GO:0016124	biolink:NamedThing	xanthophyll catabolic process	The chemical reactions and pathways resulting in the breakdown of xanthophylls, oxygen-containing carotenoids.	tmpzr1t_l9r_go_relaxed.owl	xanthophyll degradation|xanthophyll catabolism|xanthophyll breakdown													biological_process											owl:Class	
GO:0047537	biolink:NamedThing	2-aminohexanoate transaminase activity	Catalysis of the reaction: L-2-aminohexanoate + 2-oxoglutarate = 2-oxohexanoate + L-glutamate.	tmpzr1t_l9r_go_relaxed.owl	norleucine transaminase activity|norleucine aminotransferase activity|leucine L-norleucine: 2-oxoglutarate aminotransferase activity|L-2-aminohexanoate:2-oxoglutarate aminotransferase activity|norleucine (leucine) aminotransferase activity|2-aminohexanoate aminotransferase activity				RHEA:23600|EC:2.6.1.67|MetaCyc:2-AMINOHEXANOATE-AMINOTRANSFERASE-RXN									molecular_function											owl:Class	
GO:0044596	biolink:NamedThing	3-demethylubiquinol-10 3-O-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + 3-demethylubiquinol-10 = S-adenosyl-L-homocysteine + ubiquinol-10.	tmpzr1t_l9r_go_relaxed.owl					RHEA:44412|MetaCyc:RXN-9237|Reactome:R-HSA-2162186			jl	2012-04-26T04:54:11Z					molecular_function											owl:Class	
GO:0061542	biolink:NamedThing	3-demethylubiquinol-n 3-O-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + 3-demethylubiquinol-n = S-adenosyl-L-homocysteine + ubiquinol-n.	tmpzr1t_l9r_go_relaxed.owl	5-demethylubiquinone-10 methyltransferase|OMHMB-methyltransferase|2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinone methyltransferase|5-demethylubiquinone-9 methyltransferase|S-adenosyl-L-methionine:2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinone-O-methyltransferase							dph	2013-06-25T08:01:46Z					molecular_function											owl:Class	
GO:1900915	biolink:NamedThing	negative regulation of octadecene biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of octadecene biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	downregulation of octadecene formation|down-regulation of octadecene biosynthesis|downregulation of 1-octadecene biosynthetic process|down regulation of octadecene biosynthesis|negative regulation of 1-octadecene biosynthetic process|inhibition of octadecene biosynthetic process|negative regulation of octadecene biosynthesis|down-regulation of octadecene biosynthetic process|negative regulation of octadecene formation|downregulation of octadecene biosynthetic process|inhibition of octadecene formation|down regulation of octadecene synthesis|down regulation of octadecene biosynthetic process|down-regulation of octadecene anabolism|inhibition of octadecene anabolism|down regulation of octadecene formation|downregulation of octadecene synthesis|negative regulation of octadecene synthesis|downregulation of octadecene anabolism|down-regulation of octadecene formation|down regulation of octadecene anabolism|inhibition of octadecene biosynthesis|inhibition of octadecene synthesis|down-regulation of octadecene synthesis|downregulation of octadecene biosynthesis|down-regulation of 1-octadecene biosynthetic process|down regulation of 1-octadecene biosynthetic process|negative regulation of octadecene anabolism|inhibition of 1-octadecene biosynthetic process							tt	2012-06-13T04:24:47Z					biological_process											owl:Class	
GO:1902384	biolink:NamedThing	glycyrrhetinate metabolic process	The chemical reactions and pathways involving glycyrrhetinate.	tmpzr1t_l9r_go_relaxed.owl	glycyrrhetinate metabolism							ms	2013-09-03T12:55:55Z					biological_process											owl:Class	
GO:1902522	biolink:NamedThing	response to 4'-epidoxorubicin	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 4'-epidoxorubicin stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to epirubicin					Note that this term is in the subset of terms that should not be used for direct manual annotation of gene products. It was created to be used for cross-referencing by other ontologies. Direct annotations to this term may be amended during annotation QC.		dw	2013-12-02T09:44:31Z					biological_process											owl:Class	
GO:0140412	biolink:NamedThing	zinc:bicarbonate symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: zinc(out) + HCO3-(out) = zinc(in) + HCO3-(in).	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/18345						pg	2020-01-07T18:43:02Z					molecular_function											owl:Class	
GO:0004354	biolink:NamedThing	glutamate dehydrogenase (NADP+) activity	Catalysis of the reaction: L-glutamate + H2O + NADP+ = 2-oxoglutarate + NH3 + NADPH + H+.	tmpzr1t_l9r_go_relaxed.owl	L-glutamic acid dehydrogenase activity|dehydrogenase, glutamate (nicotinamide adenine dinucleotide (phosphate))|NAD(P)H-dependent glutamate dehydrogenase activity|L-glutamate dehydrogenase|glutamic acid dehydrogenase|NAD(P)-glutamate dehydrogenase activity|glutamic dehydrogenase activity|L-glutamate:NADP+ oxidoreductase (deaminating)				EC:1.4.1.4|RHEA:11612|MetaCyc:GLUTDEHYD-RXN|MetaCyc:GLUTSYNIII-PWY									molecular_function											owl:Class	
GO:0004353	biolink:NamedThing	glutamate dehydrogenase [NAD(P)+] activity	Catalysis of the reaction: L-glutamate + H2O + NAD(P)+ = 2-oxoglutarate + NH3 + NAD(P)H + H+.	tmpzr1t_l9r_go_relaxed.owl	glutamate biosynthesis, using glutamate dehydrogenase (NAD(P)+)|glutamate biosynthetic process, using glutamate dehydrogenase (NAD(P)+)|glutamic dehydrogenase activity|L-glutamate:NAD(P)+ oxidoreductase (deaminating)				Reactome:R-HSA-70589|Reactome:R-HSA-70600|EC:1.4.1.3|MetaCyc:GLUTAMATE-DEHYDROGENASE-NADP+-RXN|MetaCyc:GLUTAMATE-SYN2-PWY	Note that this term has a MetaCyc pathway reference as the pathway only has a single step.								molecular_function											owl:Class	
GO:0017151	biolink:NamedThing	DEAD/H-box RNA helicase binding	Binding to a DEAD/H-box RNA helicase.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1901058	biolink:NamedThing	p-hydroxyphenyl lignin metabolic process	The chemical reactions and pathways involving p-hydroxyphenyl lignin.	tmpzr1t_l9r_go_relaxed.owl	H-lignin metabolic process|p-hydroxyphenyl lignin metabolism							tt	2012-06-29T12:31:57Z					biological_process											owl:Class	
GO:0009808	biolink:NamedThing	lignin metabolic process	The chemical reactions and pathways involving lignins, a class of polymers of phenylpropanoid units.	tmpzr1t_l9r_go_relaxed.owl	lignin metabolism													biological_process											owl:Class	
GO:0001821	biolink:NamedThing	histamine secretion	The regulated release of histamine by a cell or tissue. It is formed by decarboxylation of histidine and it acts through receptors in smooth muscle and in secretory systems.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0046903	biolink:NamedThing	secretion	The controlled release of a substance by a cell or a tissue.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0015226	biolink:NamedThing	carnitine transmembrane transporter activity	Enables the transfer of carnitine across a membrane. Carnitine is a compound that participates in the transfer of acyl groups across the inner mitochondrial membrane.	tmpzr1t_l9r_go_relaxed.owl	vitamin Bt transporter activity				Reactome:R-HSA-164967|Reactome:R-HSA-5625674|Reactome:R-HSA-549297|Reactome:R-HSA-165026									molecular_function											owl:Class	
GO:2001192	biolink:NamedThing	negative regulation of gamma-delta T cell activation involved in immune response	Any process that stops, prevents or reduces the frequency, rate or extent of gamma-delta T cell activation involved in immune response.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of gamma-delta T-lymphocyte activation during immune response|negative regulation of gamma-delta T-cell activation during immune response|negative regulation of gamma-delta T cell activation during immune response|negative regulation of gamma-delta T lymphocyte activation during immune response							yaf	2011-11-03T04:28:44Z					biological_process											owl:Class	
GO:0046644	biolink:NamedThing	negative regulation of gamma-delta T cell activation	Any process that stops, prevents, or reduces the frequency, rate or extent of gamma-delta T cell activation.	tmpzr1t_l9r_go_relaxed.owl	down regulation of gamma-delta T cell activation|negative regulation of gamma-delta T-cell activation|downregulation of gamma-delta T cell activation|negative regulation of gamma-delta T lymphocyte activation|inhibition of gamma-delta T cell activation|negative regulation of gamma-delta T-lymphocyte activation|down-regulation of gamma-delta T cell activation													biological_process											owl:Class	
GO:0031823	biolink:NamedThing	type 1D serotonin receptor binding	Binding to a type 1D serotonin receptor.	tmpzr1t_l9r_go_relaxed.owl	5-hydroxytryptamine 1D receptor binding|type 1D serotonin receptor ligand													molecular_function											owl:Class	
GO:0031821	biolink:NamedThing	G protein-coupled serotonin receptor binding	Binding to a metabotropic serotonin receptor.	tmpzr1t_l9r_go_relaxed.owl	metabotropic 5-hydroxytryptamine receptor binding|G-protein coupled serotonin receptor binding|metabotropic serotonin receptor binding|metabotropic serotonin receptor ligand													molecular_function											owl:Class	
GO:0046610	biolink:NamedThing	lysosomal proton-transporting V-type ATPase, V0 domain	The V0 domain of a proton-transporting V-type ATPase found in the lysosomal membrane.	tmpzr1t_l9r_go_relaxed.owl	lysosomal hydrogen ion-transporting ATPase V0 domain													cellular_component											owl:Class	
GO:0000220	biolink:NamedThing	vacuolar proton-transporting V-type ATPase, V0 domain	The V0 domain of a proton-transporting V-type ATPase found in the vacuolar membrane.	tmpzr1t_l9r_go_relaxed.owl	vacuolar hydrogen ion-transporting ATPase V0 domain					Note that this domain often consists of five subunits, although in some mammalian tissues it may have an additional subunit.								cellular_component											owl:Class	
GO:0035360	biolink:NamedThing	positive regulation of peroxisome proliferator activated receptor signaling pathway	Any process that activates or increases the frequency, rate or extent of the peroxisome proliferator activated receptor signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of PPAR signaling pathway|positive regulation of peroxisome proliferator-activated receptor signaling pathway|positive regulation of peroxisome proliferator activated receptor signalling pathway							bf	2010-03-05T10:43:10Z					biological_process											owl:Class	
GO:0019828	biolink:NamedThing	aspartic-type endopeptidase inhibitor activity	Binds to and stops, prevents or reduces the activity of aspartic-type endopeptidases, enzymes that catalyze the hydrolysis of nonterminal peptide bonds in a polypeptide chain; the optimum reaction pH is below 5 due to an aspartic residue involved in the catalytic process.	tmpzr1t_l9r_go_relaxed.owl	aspartic protease inhibitor activity													molecular_function											owl:Class	
GO:0010799	biolink:NamedThing	regulation of peptidyl-threonine phosphorylation	Any process that modulates the frequency, rate or extent of peptidyl-threonine phosphorylation. Peptidyl-threonine phosphorylation is the phosphorylation of peptidyl-threonine to form peptidyl-O-phospho-L-threonine.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0075252	biolink:NamedThing	regulation of uredospore formation	Any process that modulates the frequency, rate or extent of uredospore formation, a process in which an asexual, dikaryotic, often rusty-colored spore, is formed in a structure called a uredinium.	tmpzr1t_l9r_go_relaxed.owl	regulation of ureidospore formation													biological_process											owl:Class	
GO:1901434	biolink:NamedThing	regulation of toluene catabolic process	Any process that modulates the frequency, rate or extent of toluene catabolic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of toluene breakdown|regulation of toluene catabolism|regulation of toluene degradation							tt	2012-10-01T21:12:31Z					biological_process											owl:Class	
GO:0033660	biolink:NamedThing	suppression by symbiont of host resistance gene-dependent defense response	Any process in which a symbiont stops, prevents, or reduces the frequency, rate or extent of the resistance gene-dependent defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	inhibition by symbiont of host resistance gene-dependent defense response|negative regulation by symbiont of host resistance gene-dependent defense response|down-regulation by symbiont of host gene-for-gene resistance|downregulation by symbiont of pathogen-race/host plant cultivar-specific resistance in symbiont|down regulation by symbiont of defense response in host by specific elicitors													biological_process											owl:Class	
GO:0044414	biolink:NamedThing	suppression of host defenses by symbiont	Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of host defense(s) by active mechanisms that normally result in the shutting down of a host pathway. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	downregulation by organism of defense response of other organism during symbiotic interaction|down regulation by symbiont of host defense response|down-regulation by symbiont of host defense response|inhibition by symbiont of host defense response|suppression of defense response of other organism involved in symbiotic interaction|inhibition by organism of defense response of other organism during symbiotic interaction|suppression of defenses of other organism involved in symbiotic interaction|negative regulation by organism of defense response of other organism involved in symbiotic interaction|downregulation by symbiont of host defense response|suppression of defense response of other organism|negative regulation by symbiont of host defense response|negative regulation of host defenses|negative regulation by organism of defense response of other organism during symbiotic interaction|suppression of host defense response|down-regulation by organism of defense response of other organism during symbiotic interaction|down regulation by organism of defense response of other organism during symbiotic interaction											GO:0052037|GO:0051833|GO:0052261		biological_process											owl:Class	
GO:1905070	biolink:NamedThing	anterior visceral endoderm cell migration	The orderly movement of an anterior visceral endoderm cell from one site to another.	tmpzr1t_l9r_go_relaxed.owl								cls	2016-03-21T15:18:32Z					biological_process											owl:Class	
GO:0072740	biolink:NamedThing	cellular response to anisomycin	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an anisomycin stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2012-07-17T10:33:00Z					biological_process											owl:Class	
GO:0072739	biolink:NamedThing	response to anisomycin	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an anisomycin stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2012-07-17T10:33:00Z					biological_process											owl:Class	
GO:1903344	biolink:NamedThing	regulation of protein polyglycylation	Any process that modulates the frequency, rate or extent of protein polyglycylation.	tmpzr1t_l9r_go_relaxed.owl								sart	2014-08-19T09:32:08Z					biological_process											owl:Class	
GO:0051615	biolink:NamedThing	histamine uptake	The directed movement of histamine into a cell, typically presynaptic neurons or glial cells. Histamine is a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans.	tmpzr1t_l9r_go_relaxed.owl	histamine import													biological_process											owl:Class	
GO:0051608	biolink:NamedThing	histamine transport	The directed movement of histamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Histamine is a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1905080	biolink:NamedThing	negative regulation of cerebellar neuron development	Any process that stops, prevents or reduces the frequency, rate or extent of cerebellar neuron development.	tmpzr1t_l9r_go_relaxed.owl	downregulation of cerebellar neuron development|inhibition of cerebellar neuron development|down regulation of cerebellar neuron development|down-regulation of cerebellar neuron development							hjd	2016-03-24T19:45:26Z					biological_process											owl:Class	
GO:0045665	biolink:NamedThing	negative regulation of neuron differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of neuron differentiation.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of neuron differentiation|inhibition of neuron differentiation|downregulation of neuron differentiation|down regulation of neuron differentiation													biological_process											owl:Class	
GO:0034381	biolink:NamedThing	plasma lipoprotein particle clearance	The process in which a lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.	tmpzr1t_l9r_go_relaxed.owl	lipoprotein particle clearance													biological_process											owl:Class	
GO:0035731	biolink:NamedThing	dinitrosyl-iron complex binding	Binding to a dinitrosyl-iron complex. Nitric oxide (NO) is stored as dinitrosyl-iron complexes, which form spontaneously from Glutathione (GSH), S-nitrosoglutathione, and trace amounts of ferrous ions, or by reaction of iron-sulfur centers with NO.	tmpzr1t_l9r_go_relaxed.owl	DNDGIC binding|dinitrosyl-diglutathionyl-iron complex binding|DNIC binding							bf	2011-03-11T09:58:31Z					molecular_function											owl:Class	
GO:0034811	biolink:NamedThing	benzo(a)pyrene 9,10-dioxygenase activity	Catalysis of the reaction: benzo(a)pyrene + O2 = benzo(a)pyrene-cis-9,10-dihydrodiol.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r1132|EC:1.13.11.-									molecular_function											owl:Class	
GO:0010678	biolink:NamedThing	negative regulation of cellular carbohydrate metabolic process by negative regulation of transcription, DNA-templated	Any cellular process that decreases the rate, extent or frequency of the chemical reactions and pathways involving carbohydrates carried out by repression of transcription.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of cellular carbohydrate metabolic process by repression of transcription|negative regulation of cellular carbohydrate metabolic process by negative regulation of transcription, DNA-dependent|negative regulation of cellular carbohydrate metabolic process by transcriptional repression													biological_process											owl:Class	
GO:0010677	biolink:NamedThing	negative regulation of cellular carbohydrate metabolic process	Any process that decreases the rate, extent or frequency of the chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y, as carried out by individual cells.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1903317	biolink:NamedThing	regulation of protein maturation	Any process that modulates the frequency, rate or extent of protein maturation.	tmpzr1t_l9r_go_relaxed.owl								vw	2014-08-18T12:59:07Z					biological_process											owl:Class	
GO:0086018	biolink:NamedThing	SA node cell to atrial cardiac muscle cell signaling	Any process that mediates the transfer of information from an SA node cardiomyocyte to an atrial cardiomyocyte.	tmpzr1t_l9r_go_relaxed.owl	sinoatrial node cardiomyocyte to atrial cardiomyocyte signalling|sinus node cardiomyocyte to atrial cardiomyocyte signalling|SAN cardiomyocyte to atrial cardiomyocyte signalling|SA node cardiac muscle cell to atrial cardiac muscle cell signalling|SA node cardiomyocyte to atrial cardiomyocyte signalling							tb	2011-11-10T09:15:01Z					biological_process											owl:Class	
GO:0086019	biolink:NamedThing	cell-cell signaling involved in cardiac conduction	Any process that mediates the transfer of information from one cell to another and contributes to the heart process that regulates cardiac muscle contraction; beginning with the generation of an action potential in the sinoatrial node and ending with regulation of contraction of the myocardium.	tmpzr1t_l9r_go_relaxed.owl	cell-cell signalling involved in cardiac conduction							dph	2011-11-16T03:43:52Z					biological_process											owl:Class	
GO:0005302	biolink:NamedThing	L-tyrosine transmembrane transporter activity	Enables the transfer of L-tyrosine from one side of a membrane to the other. L-tyrosine is 2-amino-3-(4-hydroxyphenyl)propanoic acid.	tmpzr1t_l9r_go_relaxed.owl	valine/tyrosine/tryptophan permease activity|L-tyrosine transporter activity|L-tyrosine permease activity											GO:0015508		molecular_function											owl:Class	
GO:0032307	biolink:NamedThing	negative regulation of prostaglandin secretion	Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a prostaglandin from a cell.	tmpzr1t_l9r_go_relaxed.owl	down regulation of prostaglandin secretion|down-regulation of prostaglandin secretion|inhibition of prostaglandin secretion|downregulation of prostaglandin secretion|negative regulation of prostacyclin secretion													biological_process											owl:Class	
GO:0032304	biolink:NamedThing	negative regulation of icosanoid secretion	Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of an icosanoid from a cell.	tmpzr1t_l9r_go_relaxed.owl	inhibition of icosanoid secretion|down-regulation of icosanoid secretion|negative regulation of eicosanoid secretion|down regulation of icosanoid secretion|downregulation of icosanoid secretion													biological_process											owl:Class	
GO:0010980	biolink:NamedThing	positive regulation of vitamin D 24-hydroxylase activity	Any process that increases the rate, frequency or extent of vitamin D 24-hydroxylase activity. Vitamin D 24-hydroxylase activity catalyzes the hydroxylation of C-24 of any form of vitamin D.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-06-01T11:47:19Z					biological_process											owl:Class	
GO:0010979	biolink:NamedThing	regulation of vitamin D 24-hydroxylase activity	Any process that modulates the rate, frequency or extent of vitamin D 24-hydroxylase activity. Vitamin D 24-hydroxylase activity catalyzes the hydroxylation of C-24 of any form of vitamin D.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-06-01T11:44:54Z					biological_process											owl:Class	
GO:0090405	biolink:NamedThing	unicellular trichome branch	A cell projection part that is a branch of a unicellular trichome.	tmpzr1t_l9r_go_relaxed.owl						Unicellular trichome (PO:0025537) is a trichome(PO:0000282) that is a single plant cell (PO:0009002). For a cell that forms a branch of a multicellular trichome, see multicellular trichome branch cell (PO:0025163).		tb	2011-01-10T10:30:39Z					cellular_component											owl:Class	
GO:0035166	biolink:NamedThing	post-embryonic hemopoiesis	The stages of blood cell formation that take place after completion of embryonic development.	tmpzr1t_l9r_go_relaxed.owl	post-embryonic haemopoiesis													biological_process											owl:Class	
GO:0019466	biolink:NamedThing	ornithine catabolic process via proline	The chemical reactions and pathways resulting in the breakdown of ornithine, via the intermediate proline.	tmpzr1t_l9r_go_relaxed.owl	ornithine breakdown via proline|ornithine degradation via proline				MetaCyc:ORN-AMINOPENTANOATE-CAT-PWY									biological_process											owl:Class	
GO:0006593	biolink:NamedThing	ornithine catabolic process	The chemical reactions and pathways resulting in the breakdown of ornithine, an amino acid only rarely found in proteins, but which is important in living organisms as an intermediate in the reactions of the urea cycle and in arginine biosynthesis.	tmpzr1t_l9r_go_relaxed.owl	ornithine catabolism|ornithine degradation|ornithine breakdown													biological_process											owl:Class	
GO:1902238	biolink:NamedThing	regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator	Any process that modulates the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator.	tmpzr1t_l9r_go_relaxed.owl								pr	2013-06-19T14:00:34Z					biological_process											owl:Class	
GO:1902218	biolink:NamedThing	regulation of intrinsic apoptotic signaling pathway in response to osmotic stress	Any process that modulates the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to osmotic stress.	tmpzr1t_l9r_go_relaxed.owl								rl	2013-06-13T10:19:07Z					biological_process											owl:Class	
GO:0006141	biolink:NamedThing	regulation of purine nucleobase metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving purines.	tmpzr1t_l9r_go_relaxed.owl	regulation of purine base metabolic process|regulation of purine base metabolism													biological_process											owl:Class	
GO:1904030	biolink:NamedThing	negative regulation of cyclin-dependent protein kinase activity	Any process that stops, prevents or reduces the frequency, rate or extent of cyclin-dependent protein kinase activity.	tmpzr1t_l9r_go_relaxed.owl	down regulation of cyclin-dependent protein kinase activity|downregulation of cyclin-dependent protein kinase activity|down-regulation of cyclin-dependent protein kinase activity|inhibition of cyclin-dependent protein kinase activity							als	2015-03-13T15:43:44Z					biological_process											owl:Class	
GO:0018420	biolink:NamedThing	peptide cross-linking via N6-(L-isoaspartyl)-L-lysine	The formation of isopeptide bonds by ligation of peptidyl-lysine and peptidyl-asparagine residues.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0294									biological_process											owl:Class	
GO:0018196	biolink:NamedThing	peptidyl-asparagine modification	The modification of peptidyl-asparagine.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0004719	biolink:NamedThing	protein-L-isoaspartate (D-aspartate) O-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + protein L-beta-aspartate = S-adenosyl-L-homocysteine + protein L-beta-aspartate methyl ester.	tmpzr1t_l9r_go_relaxed.owl	L-isoaspartyl/D-aspartyl protein carboxyl methyltransferase activity|protein O-methyltransferase (L-isoaspartate)|protein (D-aspartate) methyltransferase activity|D-aspartyl/L-isoaspartyl methyltransferase activity|protein beta-aspartate O-methyltransferase activity|L-aspartyl/L-isoaspartyl protein methyltransferase activity|S-adenosyl-L-methionine:protein-L-isoaspartate O-methyltransferase activity|protein L-isoaspartyl methyltransferase activity|protein D-aspartate methyltransferase activity|protein L-isoaspartate methyltransferase activity|protein-L-isoaspartate(D-aspartate) O-methyltransferase activity|L-isoaspartyl protein carboxyl methyltransferase activity|protein-L-isoaspartate O-methyltransferase activity|protein-beta-aspartate O-methyltransferase activity				MetaCyc:2.1.1.77-RXN|RHEA:12705|EC:2.1.1.77|Reactome:R-HSA-5676966									molecular_function											owl:Class	
GO:0089708	biolink:NamedThing	L-histidine transmembrane export from vacuole	The directed movement of L-histidine out of the vacuole, across the vacuolar membrane.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0036104	biolink:NamedThing	Kdo2-lipid A biosynthetic process	The chemical reactions and pathways resulting in the formation of Kdo2-lipid A, a lipopolysaccharide (LPS) component.	tmpzr1t_l9r_go_relaxed.owl	Kdo2-lipid A anabolism|Kdo2-lipid A synthesis|di[3-deoxy-D-manno-octulosonyl]-lipid A biosynthesis|Kdo2-lipid A biosynthesis|Kdo2-lipid A formation|KDO(2)-lipid A biosynthesis							bf	2012-01-27T01:49:23Z					biological_process											owl:Class	
GO:0009247	biolink:NamedThing	glycolipid biosynthetic process	The chemical reactions and pathways resulting in the formation of glycolipid, a class of 1,2-di-O-acylglycerols joined at oxygen 3 by a glycosidic linkage to a carbohydrate part (usually a mono-, di- or tri-saccharide).	tmpzr1t_l9r_go_relaxed.owl	glycolipid anabolism|glycolipid biosynthesis|glycolipid synthesis|glycolipid formation				MetaCyc:PWY-401									biological_process											owl:Class	
GO:0002527	biolink:NamedThing	vasodilation involved in acute inflammatory response	An increase in the internal diameter of blood vessels, especially arterioles or capillaries, usually resulting in a decrease in blood pressure contributing to an acute inflammatory response.	tmpzr1t_l9r_go_relaxed.owl	vasodilation during acute inflammatory response													biological_process											owl:Class	
GO:0009923	biolink:NamedThing	fatty acid elongase complex	A tetrameric complex of four different subunits which catalyzes the elongation of fatty acids chains 2 carbon units at a time in the synthesis of very long chain fatty acids.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0060585	biolink:NamedThing	positive regulation of prostaglandin-endoperoxide synthase activity	Any process that increases the rate, frequency or extent of prostaglandin-endoperoxide synthase activity. Prostaglandin-endoperoxide synthase activity is the catalysis of the reaction: arachidonate + donor-H2 + 2 O2 = prostaglandin H2 + acceptor + H2O.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of (PG)H synthase activity|positive regulation of PG synthetase activity|positive regulation of prostaglandin synthetase activity|positive regulation of fatty acid cyclooxygenase activity							dph	2009-05-08T02:12:34Z					biological_process											owl:Class	
GO:2000617	biolink:NamedThing	positive regulation of histone H3-K9 acetylation	Any process that activates or increases the frequency, rate or extent of histone H3-K9 acetylation.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of histone H3 acetylation at K9|positive regulation of histone H3K9 acetylation							vk	2011-04-18T03:16:07Z					biological_process											owl:Class	
GO:0004806	biolink:NamedThing	triglyceride lipase activity	Catalysis of the reaction: triacylglycerol + H2O = diacylglycerol + a carboxylate.	tmpzr1t_l9r_go_relaxed.owl	steapsin|takedo 1969-4-9|tweenase activity|triolein hydrolase activity|triacylglycerol lipase activity|GA 56|triglyceridase activity|tweenesterase activity|amano P|tributyrinase activity|liver lipase|TAG activity|triglyceride hydrolase activity|PPL|meito MY 30|tween-hydrolyzing esterase activity|butyrinase activity|triacetinase activity|salt-resistant post-heparin lipase|hepatic monoacylglycerol acyltransferase|tween hydrolase activity|lipazin|triacylglycerol acylhydrolase activity|amno N-AP|glycerol ester hydrolase activity|triacylglycerol ester hydrolase activity|post-heparin plasma protamine-resistant lipase|glycerol-ester hydrolase activity|heparin releasable hepatic lipase|amano CE|amano AP|meito sangyo OF lipase|hepatic lipase|amano CES|amano B|GEH|capalase L|tributyrin esterase activity|tributyrase activity|cacordase activity				Reactome:R-HSA-1482777|Reactome:R-HSA-163551|EC:3.1.1.3|MetaCyc:TRIACYLGLYCEROL-LIPASE-RXN|Reactome:R-HSA-8848338|RHEA:12044|Reactome:R-HSA-5694109|Reactome:R-HSA-8848339									molecular_function											owl:Class	
GO:0016298	biolink:NamedThing	lipase activity	Catalysis of the hydrolysis of a lipid or phospholipid.	tmpzr1t_l9r_go_relaxed.owl					EC:3.1.1.-|Reactome:R-HSA-163432|Reactome:R-HSA-163402									molecular_function											owl:Class	
GO:0034163	biolink:NamedThing	regulation of toll-like receptor 9 signaling pathway	Any process that modulates the frequency, rate, or extent of toll-like receptor 9 signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	regulation of TLR9 signaling pathway|regulation of toll-like receptor 9 signalling pathway													biological_process											owl:Class	
GO:0050684	biolink:NamedThing	regulation of mRNA processing	Any process that modulates the frequency, rate or extent of mRNA processing, those processes involved in the conversion of a primary mRNA transcript into a mature mRNA prior to its translation into polypeptide.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1900407	biolink:NamedThing	regulation of cellular response to oxidative stress	Any process that modulates the frequency, rate or extent of cellular response to oxidative stress.	tmpzr1t_l9r_go_relaxed.owl	regulation of adaptive response to oxidative stress							mah	2012-04-20T03:30:52Z					biological_process											owl:Class	
GO:1904029	biolink:NamedThing	regulation of cyclin-dependent protein kinase activity	Any process that modulates the frequency, rate or extent of cyclin-dependent protein kinase activity.	tmpzr1t_l9r_go_relaxed.owl								als	2015-03-13T15:43:38Z					biological_process											owl:Class	
GO:1900869	biolink:NamedThing	tatiopterin metabolic process	The chemical reactions and pathways involving tatiopterin.	tmpzr1t_l9r_go_relaxed.owl	tatiopterin metabolism							tt	2012-06-12T04:43:57Z					biological_process											owl:Class	
GO:0005212	biolink:NamedThing	structural constituent of eye lens	The action of a molecule that contributes to the structural integrity of the lens of an eye.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0140507	biolink:NamedThing	granzyme-mediated programmed cell death signaling pathway	A series of molecular signals induced by granzymes which triggers the cell death of a cell. The pathway starts with reception of a granzyme signal, and ends when the execution phase of cell death is triggered. Granzymes are serine proteases that are secreted by cytotoxic T cells and natural killer cells to induce cell death in target cells.	tmpzr1t_l9r_go_relaxed.owl	granzyme-mediated cell death signaling pathway	https://github.com/geneontology/go-ontology/issues/19901|http://wiki.geneontology.org/index.php/Apoptosis_Curation_Manual#Other_children_of_apoptotic_signaling_pathway						pg	2020-08-27T13:51:40Z					biological_process											owl:Class	
GO:2000053	biolink:NamedThing	regulation of Wnt signaling pathway involved in dorsal/ventral axis specification	Any process that modulates the frequency, rate or extent of Wnt signaling pathway involved in dorsal/ventral axis specification.	tmpzr1t_l9r_go_relaxed.owl	regulation of Wnt receptor signaling pathway involved in dorsal/ventral axis specification|regulation of Wnt-activated signaling pathway involved in dorsal/ventral axis specification|regulation of Wnt receptor signalling pathway involved in dorsal/ventral axis specification							jl	2010-08-20T01:13:28Z					biological_process											owl:Class	
GO:0047691	biolink:NamedThing	aspulvinone dimethylallyltransferase activity	Catalysis of the reaction: aspulvinone E + 2 dimethylallyl diphosphate = aspulvinone H + 2 diphosphate.	tmpzr1t_l9r_go_relaxed.owl	dimethylallyl-diphosphate:aspulvinone-E dimethylallyltransferase activity|dimethylallyl pyrophosphate:aspulvinone dimethylallyltransferase activity				RHEA:13809|KEGG_REACTION:R03799|EC:2.5.1.35|MetaCyc:ASPULVINONE-DIMETHYLALLYLTRANSFERASE-RXN									molecular_function											owl:Class	
GO:0015362	biolink:NamedThing	high-affinity sodium:dicarboxylate symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: dicarboxylate(out) + Na+(out) = dicarboxylate(in) + Na+(in). In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.	tmpzr1t_l9r_go_relaxed.owl	high affinity sodium:dicarboxylate cotransporter activity|high affinity sodium:dicarboxylate symporter activity				Reactome:R-HSA-433101									molecular_function											owl:Class	
GO:0017153	biolink:NamedThing	sodium:dicarboxylate symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: dicarboxylate(out) + Na+(out) = dicarboxylate(in) + Na+(in).	tmpzr1t_l9r_go_relaxed.owl	sodium:dicarboxylate cotransporter activity													molecular_function											owl:Class	
GO:0005280	biolink:NamedThing	amino acid:proton symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: amino acid(out) + H+(out) = amino acid(in) + H+(in).	tmpzr1t_l9r_go_relaxed.owl	cation/amino acid symporter|hydrogen:amino acid symporter activity				Reactome:R-HSA-8875623									molecular_function											owl:Class	
GO:0015295	biolink:NamedThing	solute:proton symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: solute(out) + H+(out) = solute(in) + H+(in).	tmpzr1t_l9r_go_relaxed.owl	L-idonate/D-gluconate:hydrogen symporter activity|solute:hydrogen symporter activity|low affinity metal ion uptake transporter activity|high affinity metal ion uptake transporter activity|proline/glycine/betaine:hydrogen/sodium symporter activity|heavy metal ion:hydrogen symporter activity													molecular_function											owl:Class	
GO:0062110	biolink:NamedThing	negative regulation of DNA recombinase disassembly	Any process that stops, prevents, or reduces the frequency, rate or extent of DNA recombinase complex disassembly, the disaggregation of a DNA recombinase complex into its constituent components.	tmpzr1t_l9r_go_relaxed.owl								dph	2019-02-05T13:57:35Z					biological_process											owl:Class	
GO:0004758	biolink:NamedThing	serine C-palmitoyltransferase activity	Catalysis of the reaction: L-serine + H(+) + palmitoyl-CoA = 3-dehydrosphinganine + CO(2) + CoA.	tmpzr1t_l9r_go_relaxed.owl	palmitoyl-CoA:L-serine C-palmitoyltransferase (decarboxylating) activity|serine palmitoyltransferase|SPT|3-oxosphinganine synthetase activity|acyl-CoA:serine C-2 acyltransferase decarboxylating				MetaCyc:SERINE-C-PALMITOYLTRANSFERASE-RXN|EC:2.3.1.50|KEGG_REACTION:R01281|Reactome:R-HSA-428127|RHEA:14761									molecular_function											owl:Class	
GO:0016454	biolink:NamedThing	C-palmitoyltransferase activity	Catalysis of the transfer of a palmitoyl group to a carbon atom on the acceptor molecule.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0031445	biolink:NamedThing	regulation of heterochromatin assembly	Any process that modulates the frequency, rate, extent or location of heterochromatin formation.	tmpzr1t_l9r_go_relaxed.owl	regulation of heterochromatin formation													biological_process											owl:Class	
GO:0052770	biolink:NamedThing	coenzyme F390-A hydrolase activity	Catalysis of the reaction: coenzyme F390-A = AMP + coenzyme F420.	tmpzr1t_l9r_go_relaxed.owl	8-hydroxyadenylylated-coenzyme F420 hydrolase activity							ai	2011-10-03T12:00:00Z					molecular_function											owl:Class	
GO:0016787	biolink:NamedThing	hydrolase activity	Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-1236938|EC:3.-.-.-|Reactome:R-HSA-2029475|Reactome:R-HSA-8952137|Reactome:R-HSA-5695964|Reactome:R-HSA-8938314|Reactome:R-HSA-6788295|Reactome:R-HSA-6786190|Reactome:R-HSA-5694583									molecular_function											owl:Class	
GO:0033770	biolink:NamedThing	2-hydroxyisoflavanone synthase activity	Catalysis of the reaction: apigenin + 2 NADPH + 2 H+ + O2 = 2-hydroxy-2,3-dihydrogenistein + 2 NADP+ + H2O.	tmpzr1t_l9r_go_relaxed.owl	2-HIS|apigenin,NADPH:oxygen oxidoreductase (isoflavanone-forming) activity				EC:1.14.13.86|MetaCyc:RXN-7750|RHEA:14897									molecular_function											owl:Class	
GO:0034092	biolink:NamedThing	negative regulation of maintenance of sister chromatid cohesion	Any process that decreases the extent to which the association between sister chromatids of a replicated chromosome is maintained.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0045875	biolink:NamedThing	negative regulation of sister chromatid cohesion	Any process that stops, prevents, or reduces the frequency, rate or extent of sister chromatid cohesion.	tmpzr1t_l9r_go_relaxed.owl	downregulation of sister chromatid cohesion|down regulation of sister chromatid cohesion|down-regulation of sister chromatid cohesion|inhibition of sister chromatid cohesion													biological_process											owl:Class	
GO:1903549	biolink:NamedThing	positive regulation of growth hormone activity	Any process that activates or increases the frequency, rate or extent of growth hormone activity.	tmpzr1t_l9r_go_relaxed.owl	activation of GH activity|up-regulation of GH activity|activation of pituitary growth hormone activity|positive regulation of placental growth hormone activity|upregulation of growth hormone activity|up-regulation of growth hormone activity|activation of placental growth hormone activity|upregulation of pituitary growth hormone activity|up regulation of pituitary growth hormone activity|up regulation of placental growth hormone activity|up regulation of growth hormone activity|upregulation of GH activity|positive regulation of pituitary growth hormone activity|up-regulation of pituitary growth hormone activity|up regulation of GH activity|positive regulation of GH activity|up-regulation of placental growth hormone activity|activation of growth hormone activity|upregulation of placental growth hormone activity							mr	2014-10-20T15:18:53Z					biological_process											owl:Class	
GO:1903547	biolink:NamedThing	regulation of growth hormone activity	Any process that modulates the frequency, rate or extent of growth hormone activity.	tmpzr1t_l9r_go_relaxed.owl	regulation of placental growth hormone activity|regulation of GH activity|regulation of pituitary growth hormone activity							mr	2014-10-20T15:18:36Z					biological_process											owl:Class	
GO:0075512	biolink:NamedThing	clathrin-dependent endocytosis of virus by host cell	Any clathrin-mediated endocytosis that is involved in the uptake of a virus into a host cell. Begins by invagination of a specific region of the host cell plasma membrane around the bound virus to form a clathrin-coated pit, which then pinches off to form a clathrin-coated endocytic vesicle containing the virus.	tmpzr1t_l9r_go_relaxed.owl	viral entry into host cell via clathrin-mediated endocytosis|clathrin-mediated endocytosis of virus by host cell|viral entry into host cell via clathrin-mediated endocytosis followed by endosome lysis|viral penetration via clathrin-mediated endocytosis				VZ:957			jl	2011-07-27T02:08:54Z			GO:0075516		biological_process											owl:Class	
GO:0019065	biolink:NamedThing	receptor-mediated endocytosis of virus by host cell	Any receptor-mediated endocytosis that is involved in the uptake of a virus into a host cell; successive instances of virus endocytosis result in the accumulation of virus particles within the cell.	tmpzr1t_l9r_go_relaxed.owl	viral entry into host cell via receptor-mediated endocytosis|virus receptor-mediated endocytosis by host|receptor-mediated endocytosis of virus by host|receptor mediated endocytosis by host of virus particle|viral receptor mediated endocytosis|receptor mediated endocytosis of virus particle by host|receptor mediated endocytosis of virus by host													biological_process											owl:Class	
GO:0099163	biolink:NamedThing	synaptic signaling by nitric oxide	Cell-cell signaling to or from a synapse, mediated by nitric oxide.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0099536	biolink:NamedThing	synaptic signaling	Cell-cell signaling to, from or within a synapse.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0060064	biolink:NamedThing	Spemann organizer formation at the anterior end of the primitive streak	Formation of the specialized region at the anterior end of the primitive streak of the embryo that acts as the main signaling center establishing the body plan.	tmpzr1t_l9r_go_relaxed.owl	Spemann organizer formation in amniotes|Spemann-Mangold organizer formation at the anterior end of the primitive streak|Spemann's organizer formation at the anterior end of the primitive streak					Occurs in reptiles, birds and mammals.								biological_process											owl:Class	
GO:0140317	biolink:NamedThing	export across cell outer membrane	The directed movement of a substance across the outer membrane in cells with two membranes.	tmpzr1t_l9r_go_relaxed.owl								pg	2019-04-01T08:12:23Z					biological_process											owl:Class	
GO:0006955	biolink:NamedThing	immune response	Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1900317	biolink:NamedThing	positive regulation of maltopentaose transport	Any process that activates or increases the frequency, rate or extent of maltopentaose transport.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of maltopentaose transport|upregulation of maltopentaose transport|up regulation of maltopentaose transport|activation of maltopentaose transport							tt	2012-04-05T08:00:04Z					biological_process											owl:Class	
GO:1900315	biolink:NamedThing	regulation of maltopentaose transport	Any process that modulates the frequency, rate or extent of maltopentaose transport.	tmpzr1t_l9r_go_relaxed.owl								tt	2012-04-05T07:59:47Z					biological_process											owl:Class	
GO:0072277	biolink:NamedThing	metanephric glomerular capillary formation	The process that gives rise to a metanephric glomerular capillary. This process pertains to the initial formation of a structure from unspecified parts.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-04-01T02:47:56Z					biological_process											owl:Class	
GO:0072104	biolink:NamedThing	glomerular capillary formation	The process that gives rise to a glomerular capillary. This process pertains to the initial formation of a structure from unspecified parts.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-02-10T02:40:40Z					biological_process											owl:Class	
GO:0018771	biolink:NamedThing	2-hydroxy-6-oxonona-2,4-dienedioate hydrolase activity	Catalysis of the reaction: (2E,4Z)-2-hydroxy-6-oxonona-2,4-dienedioate + H2O = (2E)-2-hydroxypenta-2,4-dienoate + H+ + succinate.	tmpzr1t_l9r_go_relaxed.owl	2-hydroxy-6-ketonona-2,4-dienedoic acid hydrolase activity|(2E,4Z)-2-hydroxy-6-oxona-2,4-dienedioate succinylhydrolase activity				RHEA:24789|EC:3.7.1.14|MetaCyc:MHPCHYDROL-RXN|UM-BBD_reactionID:r0438							GO:0008680		molecular_function											owl:Class	
GO:0033295	biolink:NamedThing	hydroxyectoine binding	Binding to hydroxyectoine.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0050997	biolink:NamedThing	quaternary ammonium group binding	Binding to a quaternary ammonium group, including glycine betaine, choline, carnitine and proline. A quaternary ammonium group is any compound that can be regarded as derived from ammonium hydroxide or an ammonium salt by replacement of all four hydrogen atoms of the NH4+ ion by organic groups.	tmpzr1t_l9r_go_relaxed.owl	quaternary amine binding													molecular_function											owl:Class	
GO:0045070	biolink:NamedThing	positive regulation of viral genome replication	Any process that activates or increases the frequency, rate or extent of viral genome replication.	tmpzr1t_l9r_go_relaxed.owl	activation of viral genome replication|upregulation of viral genome replication|stimulation of viral genome replication|up regulation of viral genome replication|up-regulation of viral genome replication													biological_process											owl:Class	
GO:0048524	biolink:NamedThing	positive regulation of viral process	Any process that activates or increases the frequency, rate or extent of a multi-organism process in which a virus is a participant.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of viral reproduction|upregulation of viral life cycle|stimulation of viral life cycle|activation of viral life cycle|up regulation of viral life cycle|up-regulation of viral life cycle|positive regulation of viral life cycle													biological_process											owl:Class	
GO:0060007	biolink:NamedThing	linear vestibuloocular reflex	A vestibular reflex by which a response to a linear acceleration stimulus begins with an afferent nerve impulse from a receptor in the otolith and ends with the compensatory action of eye muscles. Signaling never reaches a level of consciousness.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0060005	biolink:NamedThing	vestibular reflex	A reflex process in which a response to an angular or linear acceleration stimulus begins with an afferent nerve impulse from a receptor in the inner ear and ends with the compensatory action of eye muscles. Signaling never reaches a level of consciousness.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0075298	biolink:NamedThing	regulation of zygospore formation	Any process that modulates the frequency, rate or extent of zygospore formation, a process in which a thick-walled spore of some algae and fungi is formed by union of two similar sexual cells, usually serves as a resting spore, and produces the sporophytic phase.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0072572	biolink:NamedThing	poly-ADP-D-ribose binding	Binding to polymeric ADP-D-ribose, a polymer that is composed of poly-ADP-D-ribose units linked through 1,2-glycosidic bonds at the ribose ring.	tmpzr1t_l9r_go_relaxed.owl	poly-ADP-ribose binding|pADPr binding							mah	2011-01-31T02:49:04Z					molecular_function											owl:Class	
GO:0002599	biolink:NamedThing	negative regulation of antigen processing and presentation of lipid antigen via MHC class Ib	Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of lipid antigen via MHC class Ib.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of lipid antigen processing and presentation via MHC class Ib|down regulation of antigen processing and presentation of lipid antigen via MHC class Ib|down-regulation of antigen processing and presentation of lipid antigen via MHC class Ib|downregulation of antigen processing and presentation of lipid antigen via MHC class Ib|inhibition of antigen processing and presentation of lipid antigen via MHC class Ib													biological_process											owl:Class	
GO:0033470	biolink:NamedThing	gibberellin 12 biosynthetic process	The chemical reactions and pathways resulting in the formation of gibberellin 12, (1R,2S,3S,4R,8S,9S,12R)-4,8-dimethyl-13-methylidenetetracyclo[10.2.1.01,9.03,8]pentadecane-2,4-dicarboxylic acid 1meta,4a-dimethyl-8-methylidene-4aalpha,4bbeta-gibbane-1alpha,10beta-dicarboxylic acid.	tmpzr1t_l9r_go_relaxed.owl	gibberellin A12 biosynthetic process|gibberellin 12 biosynthesis|GA12 biosynthetic process|gibberellin 12 synthesis|gibberellin 12 anabolism|gibberellin 12 formation				MetaCyc:PWY-5034									biological_process											owl:Class	
GO:0033469	biolink:NamedThing	gibberellin 12 metabolic process	The chemical reactions and pathways involving gibberellin 12, (1R,2S,3S,4R,8S,9S,12R)-4,8-dimethyl-13-methylidenetetracyclo[10.2.1.01,9.03,8]pentadecane-2,4-dicarboxylic acid 1meta,4a-dimethyl-8-methylidene-4aalpha,4bbeta-gibbane-1alpha,10beta-dicarboxylic acid.	tmpzr1t_l9r_go_relaxed.owl	gibberellin 12 metabolism|GA12 metabolic process|gibberellin A12 metabolic process													biological_process											owl:Class	
GO:1901753	biolink:NamedThing	leukotriene A4 biosynthetic process	The chemical reactions and pathways resulting in the formation of leukotriene A4.	tmpzr1t_l9r_go_relaxed.owl	LTA4 biosynthesis|eoxin A4 biosynthesis|leukotriene A4 biosynthesis|leukotriene A4 formation|leukotriene A4 anabolism|leukotriene A4 synthesis	https://github.com/geneontology/go-ontology/issues/18848						yaf	2013-01-14T11:05:09Z					biological_process											owl:Class	
GO:0004392	biolink:NamedThing	heme oxygenase (decyclizing) activity	Catalysis of the reaction: heme b + 3 O2 + 3 reduced [NADPH-hemoprotein reductase] = biliverdin  + CO + Fe2+ + H+ + 3 H2O + 3 oxidized [NADPH-hemoprotein reductase].	tmpzr1t_l9r_go_relaxed.owl	haem oxygenase (decyclizing) activity|heme,hydrogen-donor:oxygen oxidoreductase (alpha-methene-oxidizing, hydroxylating)|heme oxygenase activity|haem oxidase activity|heme oxidase activity|haem oxygenase activity|ORP33 proteins	https://github.com/geneontology/go-ontology/issues/21106			MetaCyc:HEME-OXYGENASE-DECYCLIZING-RXN|RHEA:21764|Reactome:R-HSA-189398|EC:1.14.14.18									molecular_function											owl:Class	
GO:0016712	biolink:NamedThing	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from reduced flavin or flavoprotein and one other donor, and one atom of oxygen is incorporated into one donor.	tmpzr1t_l9r_go_relaxed.owl	cytochrome P450 CYP19|substrate,reduced-flavoprotein:oxygen oxidoreductase (RH-hydroxylating or -epoxidizing)|cytochrome p450 activity|microsomal p450 activity|unspecific monooxygenase activity|flavoprotein monooxygenase activity|aryl-4-monooxygenase activity|flavoprotein-linked monooxygenase activity|xenobiotic monooxygenase activity|aryl hydrocarbon hydroxylase activity|microsomal P-450|microsomal monooxygenase activity				UM-BBD_enzymeID:e0551|EC:1.14.14.-|Reactome:R-HSA-211966							GO:0050381|GO:0008402		molecular_function											owl:Class	
GO:0006672	biolink:NamedThing	ceramide metabolic process	The chemical reactions and pathways involving ceramides, any N-acylated sphingoid.	tmpzr1t_l9r_go_relaxed.owl	ceramide metabolism													biological_process											owl:Class	
GO:0060688	biolink:NamedThing	regulation of morphogenesis of a branching structure	Any process that modulates the rate, frequency, or extent of branching morphogenesis, the process in which the anatomical structures of branches are generated and organized.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-06-05T12:41:44Z					biological_process											owl:Class	
GO:1901319	biolink:NamedThing	positive regulation of trehalose catabolic process	Any process that activates or increases the frequency, rate or extent of trehalose catabolic process.	tmpzr1t_l9r_go_relaxed.owl	upregulation of trehalose catabolism|activation of mycose catabolism|up-regulation of trehalose degradation|upregulation of mykose catabolic process|activation of mycose catabolic process|up regulation of trehalose degradation|activation of mykose catabolic process|activation of trehalose catabolic process|up-regulation of mykose catabolism|activation of trehalose catabolism|up-regulation of mycose catabolism|up regulation of trehalose breakdown|up-regulation of mycose catabolic process|activation of mykose catabolism|upregulation of mycose catabolic process|up-regulation of trehalose catabolic process|positive regulation of mycose catabolism|upregulation of trehalose catabolic process|upregulation of mykose catabolism|positive regulation of mykose catabolic process|up regulation of trehalose catabolic process|upregulation of mycose catabolism|upregulation of trehalose degradation|up regulation of mycose catabolic process|up regulation of mykose catabolism|up-regulation of trehalose breakdown|activation of trehalose degradation|upregulation of trehalose breakdown|up regulation of trehalose catabolism|positive regulation of mykose catabolism|positive regulation of trehalose breakdown|up-regulation of trehalose catabolism|positive regulation of mycose catabolic process|activation of trehalose breakdown|up regulation of mykose catabolic process|up-regulation of mykose catabolic process|positive regulation of trehalose catabolism|positive regulation of trehalose degradation|up regulation of mycose catabolism							al	2012-08-24T12:57:52Z					biological_process											owl:Class	
GO:0090062	biolink:NamedThing	regulation of trehalose metabolic process	Any process that modulates the frequency, rate or extent of trehalose metabolism, the chemical reactions and pathways involving trehalose, a disaccharide isomeric with sucrose and obtained from certain lichens and fungi.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-08-12T11:24:29Z					biological_process											owl:Class	
GO:0000461	biolink:NamedThing	endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	Endonucleolytic cleavage at the 3'-end of the SSU-rRNA from an originally tricistronic rRNA transcript that contained the Small Subunit (SSU) rRNA, the 5.8S rRNA, and the Large Subunit (LSU) rRNA in that order from 5' to 3' along the primary transcript, to produce the mature end of the SSU-rRNA.	tmpzr1t_l9r_go_relaxed.owl	endonucleolytic cleavage at site D													biological_process											owl:Class	
GO:0031125	biolink:NamedThing	rRNA 3'-end processing	Any process involved in forming the mature 3' end of an rRNA molecule.	tmpzr1t_l9r_go_relaxed.owl	rRNA 3' end processing													biological_process											owl:Class	
GO:0045122	biolink:NamedThing	aflatoxin biosynthetic process	The chemical reactions and pathways resulting in the formation of aflatoxin, a fungal metabolite found as a contaminant in moldy grains that induces liver cancer. Aflatoxin induces a G to T transversion at codon 249 of p53, leading to its inactivation. Aflatoxin is converted to a chemical carcinogen by P450.	tmpzr1t_l9r_go_relaxed.owl	aflatoxin biosynthesis|aflatoxin anabolism|aflatoxin synthesis|aflatoxin formation													biological_process											owl:Class	
GO:0046222	biolink:NamedThing	aflatoxin metabolic process	The chemical reactions and pathways involving aflatoxin, a fungal metabolite found as a contaminant in moldy grains that induces liver cancer. Aflatoxin induces a G to T transversion at codon 249 of p53, leading to its inactivation. Aflatoxin is converted to a chemical carcinogen by P450.	tmpzr1t_l9r_go_relaxed.owl	aflatoxin B1 metabolic process|aflatoxin B1 metabolism|aflatoxin B2 metabolism|aflatoxin metabolism|aflatoxin B2 metabolic process|aflatoxin B metabolic process	https://github.com/geneontology/go-ontology/issues/18291										GO:0043389|GO:0043390|GO:0043391		biological_process											owl:Class	
GO:0043910	biolink:NamedThing	ATP:coenzyme F420 adenylyltransferase activity	Catalysis of the reaction: ATP + factor gamma-F420-2 + H+ = coenzyme F390-A + diphosphate.	tmpzr1t_l9r_go_relaxed.owl	coenzyme F390-A synthetase activity|ATP:coenzyme F420 adenyltransferase activity				MetaCyc:RXN-9385									molecular_function											owl:Class	
GO:0102629	biolink:NamedThing	patuletin 3'-O-methyltransferase activity	Catalysis of the reaction: patuletin + S-adenosyl-L-methionine  <=> quercetagetin 3',6-dimethyl ether + S-adenosyl-L-homocysteine  + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-15534									molecular_function											owl:Class	
GO:1901750	biolink:NamedThing	leukotriene D4 biosynthetic process	The chemical reactions and pathways resulting in the formation of leukotriene D4.	tmpzr1t_l9r_go_relaxed.owl	leukotriene D4 formation|leukotriene D4 anabolism|leukotriene D4 synthesis|leukotriene D4 biosynthesis							yaf	2013-01-14T10:56:21Z					biological_process											owl:Class	
GO:1901570	biolink:NamedThing	fatty acid derivative biosynthetic process	The chemical reactions and pathways resulting in the formation of fatty acid derivative.	tmpzr1t_l9r_go_relaxed.owl	fatty acid derivative synthesis|fatty acid derivative formation|fatty acid derivative anabolism|fatty acid derivative biosynthesis							pr	2012-11-04T17:13:44Z					biological_process											owl:Class	
GO:1904011	biolink:NamedThing	cellular response to Aroclor 1254	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an Aroclor 1254 stimulus.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-03-06T18:35:06Z					biological_process											owl:Class	
GO:1904010	biolink:NamedThing	response to Aroclor 1254	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an Aroclor 1254 stimulus.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-03-06T18:35:00Z					biological_process											owl:Class	
GO:0031539	biolink:NamedThing	positive regulation of anthocyanin metabolic process	Any process that activates or increases the frequency, rate or extent of chemical reactions and pathways involving anthocyanins.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of anthocyanin metabolic process|up regulation of anthocyanin metabolic process|stimulation of anthocyanin metabolic process|positive regulation of anthocyanin metabolism|activation of anthocyanin metabolic process|upregulation of anthocyanin metabolic process													biological_process											owl:Class	
GO:0002951	biolink:NamedThing	leukotriene-C(4) hydrolase	Catalysis of the reaction Leukotriene C(4) + H(2)O= leukotriene D(4) + L-glutamate.	tmpzr1t_l9r_go_relaxed.owl						The mouse enzyme is specific for leukotriene C(4), while the human enzyme also has considerable activity toward glutathione and oxidized glutathione (cf. EC:3.4.19.13). PMID:9774450 cites that the mouse form of this enzyme failed to measure activity towards glutathione.								molecular_function											owl:Class	
GO:0070122	biolink:NamedThing	isopeptidase activity	Catalysis of the hydrolysis of an isopeptide bond. An isopeptide bond is an amide linkage between a carboxyl group of one amino acid and an amino group of another amino acid in which at least one of these groups is not on the a-carbon of one of the amino acids (for example, the link between an epsilon-amino group of a lysine molecule to a carboxyl group on a second amino acid is an isopeptide bond).	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0005989	biolink:NamedThing	lactose biosynthetic process	The chemical reactions and pathways resulting in the formation of lactose, the disaccharide galactopyranosyl-glucose.	tmpzr1t_l9r_go_relaxed.owl	lactose anabolism|lactose formation|lactose synthesis|lactose biosynthesis													biological_process											owl:Class	
GO:0046351	biolink:NamedThing	disaccharide biosynthetic process	The chemical reactions and pathways resulting in the formation of disaccharides, sugars composed of two monosaccharide units.	tmpzr1t_l9r_go_relaxed.owl	disaccharide formation|disaccharide synthesis|disaccharide biosynthesis|disaccharide anabolism													biological_process											owl:Class	
GO:0008010	biolink:NamedThing	structural constituent of chitin-based larval cuticle	The action of a molecule that contributes to the structural integrity of the chitin-based cuticle of a larva. An example of this is found in Drosophila melanogaster.	tmpzr1t_l9r_go_relaxed.owl	structural constituent of larval cuticle													molecular_function											owl:Class	
GO:0005214	biolink:NamedThing	structural constituent of chitin-based cuticle	The action of a molecule that contributes to the structural integrity of a chitin-based cuticle. An example of this is found in Drosophila melanogaster.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1903181	biolink:NamedThing	positive regulation of dopamine biosynthetic process	Any process that activates or increases the frequency, rate or extent of dopamine biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	activation of dopamine anabolism|up regulation of dopamine biosynthetic process|up-regulation of dopamine formation|up regulation of dopamine biosynthesis|up regulation of dopamine synthesis|upregulation of dopamine anabolism|activation of dopamine biosynthetic process|activation of dopamine formation|up regulation of dopamine anabolism|positive regulation of dopamine biosynthesis|up regulation of dopamine formation|upregulation of dopamine biosynthesis|upregulation of dopamine biosynthetic process|positive regulation of dopamine formation|activation of dopamine synthesis|up-regulation of dopamine anabolism|activation of dopamine biosynthesis|positive regulation of dopamine anabolism|up-regulation of dopamine biosynthetic process|up-regulation of dopamine synthesis|upregulation of dopamine synthesis|up-regulation of dopamine biosynthesis|upregulation of dopamine formation|positive regulation of dopamine synthesis							bf	2014-07-14T12:17:53Z					biological_process											owl:Class	
GO:0032977	biolink:NamedThing	membrane insertase activity	Binds transmembrane domain-containing proteins and mediates their integration into a membrane.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/16976|https://github.com/geneontology/go-ontology/issues/20414			Reactome:R-HSA-1307803|Reactome:R-HSA-1299482|Reactome:R-HSA-1268025									molecular_function											owl:Class	
GO:0090347	biolink:NamedThing	regulation of cellular organohalogen metabolic process	Any process that modulates the rate, frequency or extent of the chemical reactions and pathways involving organohalogen compounds, as carried out by individual cells.	tmpzr1t_l9r_go_relaxed.owl								tb	2010-06-02T10:36:42Z					biological_process											owl:Class	
GO:1900691	biolink:NamedThing	positive regulation of gliotoxin biosynthetic process	Any process that activates or increases the frequency, rate or extent of gliotoxin biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of gliotoxin anabolism|positive regulation of gliotoxin synthesis|upregulation of gliotoxin biosynthetic process|up-regulation of gliotoxin formation|activation of gliotoxin synthesis|up regulation of gliotoxin formation|up regulation of gliotoxin anabolism|upregulation of gliotoxin synthesis|up-regulation of gliotoxin anabolism|activation of gliotoxin anabolism|positive regulation of gliotoxin biosynthesis|activation of gliotoxin biosynthesis|up regulation of gliotoxin biosynthetic process|up-regulation of gliotoxin biosynthesis|activation of gliotoxin biosynthetic process|up regulation of gliotoxin synthesis|up regulation of gliotoxin biosynthesis|up-regulation of gliotoxin biosynthetic process|up-regulation of gliotoxin synthesis|upregulation of gliotoxin biosynthesis|upregulation of gliotoxin formation|upregulation of gliotoxin anabolism|positive regulation of gliotoxin formation|activation of gliotoxin formation							di	2012-05-22T04:52:08Z					biological_process											owl:Class	
GO:0075329	biolink:NamedThing	regulation of arbuscule formation for nutrient acquisition from host	Any process that modulates the frequency, rate or extent of symbiont arbuscule formation for nutrient acquisition from host. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl						Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products from the symbiont involved in this process.								biological_process											owl:Class	
GO:0004424	biolink:NamedThing	imidazoleglycerol-phosphate dehydratase activity	Catalysis of the reaction: D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate = 3-(imidazol-4-yl)-2-oxopropyl phosphate + H(2)O.	tmpzr1t_l9r_go_relaxed.owl	D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate hydro-lyase [3-(imidazol-4-yl)-2-oxopropyl-phosphate-forming]|imidazoleglycerol phosphate dehydratase activity|IGP dehydratase activity|D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate hydro-lyase activity				MetaCyc:IMIDPHOSDEHYD-RXN|RHEA:11040|KEGG_REACTION:R03457|EC:4.2.1.19									molecular_function											owl:Class	
GO:1901112	biolink:NamedThing	actinorhodin biosynthetic process	The chemical reactions and pathways resulting in the formation of actinorhodin.	tmpzr1t_l9r_go_relaxed.owl	actinorhodin synthesis|actinorhodin biosynthesis|actinorhodin anabolism|actinorhodin formation							yaf	2012-07-11T03:06:08Z					biological_process											owl:Class	
GO:1903098	biolink:NamedThing	negative regulation of CENP-A containing nucleosome assembly	Any process that stops, prevents or reduces the frequency, rate or extent of the formation of nucleosomes containing the histone H3 variant CENP-A to form centromeric chromatin. This specialised chromatin occurs at centromeric region in point centromeres,  and the central core in modular centromeres.	tmpzr1t_l9r_go_relaxed.owl	down regulation of CenH3-containing nucleosome assembly at centromere|negative regulation of centromere-specific nucleosome assembly|inhibition of centromeric DNA replication-independent nucleosome assembly|negative regulation of CENP-A deposition|down regulation of centromere specific nucleosome exchange|down regulation of CENP-A loading|inhibition of CENP-A loading|negative regulation of DNA replication-independent nucleosome assembly at centromere|down regulation of centromere-specific nucleosome assembly|downregulation of centromere specific nucleosome exchange|downregulation of CenH3-containing nucleosome assembly at centromere|downregulation of centromeric DNA replication-independent nucleosome assembly|inhibition of CENP-A deposition|inhibition of DNA replication-independent nucleosome assembly at centromere|down-regulation of CenH3-containing nucleosome assembly at centromere|down regulation of CENP-A containing nucleosome assembly at centromere|inhibition of centromere specific nucleosome exchange|down regulation of DNA replication-independent nucleosome assembly at centromere|down-regulation of CENP-A loading|down-regulation of CENP-A deposition|downregulation of CENP-A deposition|negative regulation of CENP-A loading|downregulation of DNA replication-independent nucleosome assembly at centromere|downregulation of centromere-specific histone exchange|down regulation of centromeric DNA replication-independent nucleosome assembly|down-regulation of centromere-specific histone exchange|downregulation of centromere-specific nucleosome assembly|down-regulation of centromere specific nucleosome exchange|downregulation of CENP-A loading|negative regulation of centromere specific nucleosome exchange|down-regulation of CENP-A containing nucleosome assembly at centromere|inhibition of CENP-A containing nucleosome assembly at centromere|inhibition of centromere-specific histone exchange|down-regulation of centromeric DNA replication-independent nucleosome assembly|inhibition of centromere-specific nucleosome assembly|negative regulation of centromere-specific histone exchange|down regulation of CENP-A deposition|negative regulation of CenH3-containing nucleosome assembly at centromere|down regulation of centromere-specific histone exchange|down-regulation of centromere-specific nucleosome assembly|inhibition of CenH3-containing nucleosome assembly at centromere|down-regulation of DNA replication-independent nucleosome assembly at centromere|downregulation of CENP-A containing nucleosome assembly at centromere|negative regulation of centromeric DNA replication-independent nucleosome assembly							vw	2014-06-03T16:15:36Z					biological_process											owl:Class	
GO:1900050	biolink:NamedThing	negative regulation of histone exchange	Any process that stops, prevents or reduces the frequency, rate or extent of histone exchange.	tmpzr1t_l9r_go_relaxed.owl	inhibition of histone chaperone|negative regulation of histone chaperone|downregulation of histone replacement|downregulation of histone exchange|inhibition of histone replacement|down-regulation of histone chaperone|down regulation of histone chaperone|inhibition of histone exchange|down regulation of histone exchange|down-regulation of histone replacement|downregulation of histone chaperone|down-regulation of histone exchange|down regulation of histone replacement|negative regulation of histone replacement							se	2012-01-19T10:59:09Z					biological_process											owl:Class	
GO:1903178	biolink:NamedThing	positive regulation of tyrosine 3-monooxygenase activity	Any process that activates or increases the frequency, rate or extent of tyrosine 3-monooxygenase activity.	tmpzr1t_l9r_go_relaxed.owl	stimulation of TH activity|upregulation of tyrosine hydroxylase activity|positive regulation of tyrosine 3-hydroxylase activity|activation of tyrosine 3-monooxygenase activity|up regulation of L-tyrosine hydroxylase activity|positive regulation of L-tyrosine hydroxylase activity|upregulation of tyrosine 3-monooxygenase activity|up-regulation of L-tyrosine hydroxylase activity|up regulation of tyrosine 3-hydroxylase activity|positive regulation of tyrosine hydroxylase activity|up regulation of tyrosine 3-monooxygenase activity|activation of L-tyrosine hydroxylase activity|up-regulation of tyrosine 3-hydroxylase activity|up-regulation of L-tyrosine,tetrahydrobiopterin:oxygen oxidoreductase (3-hydroxylating)|up regulation of tyrosine hydroxylase activity|upregulation of tyrosine 3-hydroxylase activity|upregulation of L-tyrosine,tetrahydrobiopterin:oxygen oxidoreductase (3-hydroxylating)|positive regulation of L-tyrosine,tetrahydrobiopterin:oxygen oxidoreductase (3-hydroxylating)|activation of L-tyrosine,tetrahydrobiopterin:oxygen oxidoreductase (3-hydroxylating)|upregulation of L-tyrosine hydroxylase activity|up-regulation of tyrosine hydroxylase activity|positive regulation of TH activity|activation of tyrosine 3-hydroxylase activity|activation of tyrosine hydroxylase activity|up regulation of L-tyrosine,tetrahydrobiopterin:oxygen oxidoreductase (3-hydroxylating)|up-regulation of tyrosine 3-monooxygenase activity							bf	2014-07-14T10:39:21Z					biological_process											owl:Class	
GO:0061884	biolink:NamedThing	regulation of mini excitatory postsynaptic potential	Any process that modulates the frequency, rate or extent of mini excitatory postsynaptic potential. Mini excitatory postsynaptic potential is a process that leads to a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell, induced by the spontaneous release of a single vesicle of an excitatory neurotransmitter into the synapse.	tmpzr1t_l9r_go_relaxed.owl								dph	2017-05-30T15:35:46Z					biological_process											owl:Class	
GO:1904762	biolink:NamedThing	positive regulation of myofibroblast differentiation	Any process that activates or increases the frequency, rate or extent of myofibroblast differentiation.	tmpzr1t_l9r_go_relaxed.owl	up regulation of myofibroblast cell differentiation|activation of myofibroblast cell differentiation|up regulation of myofibroblast differentiation|activation of myofibroblast differentiation|upregulation of myofibroblast differentiation|upregulation of myofibroblast cell differentiation|up-regulation of myofibroblast differentiation|up-regulation of myofibroblast cell differentiation|positive regulation of myofibroblast cell differentiation							rph	2015-10-23T12:15:17Z					biological_process											owl:Class	
GO:0072132	biolink:NamedThing	mesenchyme morphogenesis	The process in which the anatomical structures of a mesenchymal tissue are generated and organized. A mesenchymal tissue is made up of loosely packed stellate cells.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-02-22T02:17:15Z					biological_process											owl:Class	
GO:0099567	biolink:NamedThing	calcium ion binding involved in regulation of postsynaptic cytosolic calcium ion concentration	The directed change of free calcium ion concentration in the postsynaptic cytosol via the reversible binding of calcium ions to calcium-binding proteins in the cytosol thereby modulating the spatial and temporal dynamics of changes in postsynaptic cytosolic calcium concentrations.	tmpzr1t_l9r_go_relaxed.owl	regulation of postsynaptic cytosolic calcium ion concentration by calcium ion buffering|postsynaptic calcium ion buffering|calcium ion binding involved in regulation of postsynaptic cytosolic calcium levels													molecular_function											owl:Class	
GO:0005509	biolink:NamedThing	calcium ion binding	Binding to a calcium ion (Ca2+).	tmpzr1t_l9r_go_relaxed.owl	calcium ion storage activity													molecular_function											owl:Class	
GO:0009821	biolink:NamedThing	alkaloid biosynthetic process	The chemical reactions and pathways resulting in the formation of alkaloids, nitrogen-containing natural products which are not otherwise classified as nonprotein amino acids, amines, peptides, amines, cyanogenic glycosides, glucosinolates, cofactors, phytohormones, or primary metabolite (such as purine or pyrimidine bases).	tmpzr1t_l9r_go_relaxed.owl	alkaloid synthesis|alkaloid biosynthesis|alkaloid formation|alkaloid anabolism				UM-BBD_enzymeID:e0711									biological_process											owl:Class	
GO:0071395	biolink:NamedThing	cellular response to jasmonic acid stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a jasmonic acid stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-12-11T04:13:34Z					biological_process											owl:Class	
GO:2001011	biolink:NamedThing	positive regulation of plant-type cell wall cellulose biosynthetic process	Any process that activates or increases the frequency, rate or extent of plant-type cell wall cellulose biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of cell wall cellulose biosynthesis|positive regulation of cellulose biosynthesis during cell wall biosynthesis							tt	2011-08-08T08:47:30Z					biological_process											owl:Class	
GO:0097008	biolink:NamedThing	(3E)-4,8-dimethyl-1,3,7-nonatriene synthase activity	Catalysis of the reaction: (E)-nerolidol + NADPH + O2 = (3E)-4,8-dimethylnona-1,3,7-triene + NADP+ + 2 H2O. It is unknown whether this reaction proceeds by the direct release of the 4-carbon compound but-1-en-3-one, or whether the substrate is first degraded to C11-geranylacetone and then cleaved to produce (3E)-4,8-dimethylnona-1,3,7-triene (DMNT) and acetone.	tmpzr1t_l9r_go_relaxed.owl	(3E)-4,8-dimethylnona-1,3,7-triene synthase activity|DNMT synthase activity				MetaCyc:RXN-8619			pr	2011-03-17T10:38:01Z					molecular_function											owl:Class	
GO:0002767	biolink:NamedThing	immune response-inhibiting cell surface receptor signaling pathway	A series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell capable of inhibiting an immune response.	tmpzr1t_l9r_go_relaxed.owl	immune response-inhibiting cell surface receptor signalling pathway													biological_process											owl:Class	
GO:0002765	biolink:NamedThing	immune response-inhibiting signal transduction	The cascade of processes by which a signal interacts with a receptor, causing a change in the level or activity of a second messenger or other downstream target, and ultimately leading to inhibition of an immune response.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0002569	biolink:NamedThing	somatic diversification of immune receptors by N region addition	The addition of variable numbers of random nucleotides by terminal deoxytransferase in the N regions of heavy chain immunoglobulin and T cell receptor genes. N regions are found at the V-D, D-D, V-J, and D-J recombinational junctions, depending on the immune receptor gene.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0072673	biolink:NamedThing	lamellipodium morphogenesis	A process that is carried out at the cellular level and in which the structure of a lamellipodium is organized.	tmpzr1t_l9r_go_relaxed.owl	lamellipodium organization							mah	2011-02-21T03:11:55Z					biological_process											owl:Class	
GO:0120039	biolink:NamedThing	plasma membrane bounded cell projection morphogenesis	The process in which the anatomical structures of a plasma membrane bounded cell projection are generated and organized.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/13298						krc	2017-04-28T23:39:37Z					biological_process											owl:Class	
GO:2000803	biolink:NamedThing	endosomal signal transduction	The process in which a signal is passed on to downstream components located at the endosome. Endosomes can provide important intracellular signaling platforms and provide spatial and temporal control over signal transduction.	tmpzr1t_l9r_go_relaxed.owl	signalling cascade in endosome|endosome-based signaling|signaling from endosome|signaling cascade in endosome|signaling pathway in endosome|signalling pathway in endosome							bf	2011-07-01T03:45:12Z					biological_process											owl:Class	
GO:0035556	biolink:NamedThing	intracellular signal transduction	The process in which a signal is passed on to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell.	tmpzr1t_l9r_go_relaxed.owl	signal transduction via intracellular signaling cascade|intracellular signaling pathway|intracellular signaling chain|intracellular protein kinase cascade|signal transmission via intracellular cascade|intracellular signal transduction pathway|protein kinase cascade|intracellular signaling cascade							bf	2010-05-14T01:14:37Z			GO:0023034|GO:0007242|GO:0023013|GO:0007243		biological_process											owl:Class	
GO:0008735	biolink:NamedThing	carnitine dehydratase activity	Catalysis of the reaction: (R)-carnitine = crotono-betaine + H(2)O.	tmpzr1t_l9r_go_relaxed.owl	L-carnitine hydro-lyase [4-(trimethylammonio)but-2-enoate-forming]|L-carnitine dehydratase activity|L-carnitine hydro-lyase activity				KEGG_REACTION:R01925|RHEA:14577|MetaCyc:CARNDEHYDRA-RXN|EC:4.2.1.89									molecular_function											owl:Class	
GO:1900850	biolink:NamedThing	negative regulation of pseurotin A biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of pseurotin A biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	downregulation of pseurotin A biosynthetic process|down-regulation of pseurotin A biosynthetic process|down regulation of pseurotin A biosynthetic process							di	2012-06-07T09:45:49Z					biological_process											owl:Class	
GO:0120030	biolink:NamedThing	positive regulation of cilium beat frequency involved in ciliary motility	Any process that activates or increases the frequency of cilium beating involved in ciliary motility.	tmpzr1t_l9r_go_relaxed.owl								krc	2017-04-19T14:32:16Z					biological_process											owl:Class	
GO:0060296	biolink:NamedThing	regulation of cilium beat frequency involved in ciliary motility	Any process that modulates the frequency of cilium beating involved in ciliary motility.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0006016	biolink:NamedThing	2-deoxyribose 1-phosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of 2-deoxyribose 1-phosphate, the phosphorylated sugar 1-phospho-2-deoxyribose.	tmpzr1t_l9r_go_relaxed.owl	2-deoxyribose 1-phosphate anabolism|2-deoxyribose 1-phosphate formation|2-deoxyribose 1-phosphate synthesis|2-deoxyribose 1-phosphate biosynthesis													biological_process											owl:Class	
GO:0046384	biolink:NamedThing	2-deoxyribose 1-phosphate metabolic process	The chemical reactions and pathways involving 2-deoxyribose 1-phosphate, the phosphorylated sugar 1-phospho-2-deoxyribose.	tmpzr1t_l9r_go_relaxed.owl	deoxyribose 1-phosphate metabolism|2-deoxyribose 1-phosphate metabolism|deoxyribose 1-phosphate metabolic process											GO:0046388		biological_process											owl:Class	
GO:1990136	biolink:NamedThing	linoleate 9S-lipoxygenase activity	Catalysis of the reaction: linoleate + O2 = (9S,10E,12Z)-9-hydroperoxy-10,12-octadecadienoate.	tmpzr1t_l9r_go_relaxed.owl	linoleate:oxygen 9S-oxidoreductase activity|9S-lipoxygenase activity|9-lipoxygenase activity|linoleate 9-lipoxygenase activity				RHEA:30291|EC:1.13.11.58			pr	2013-07-03T12:20:57Z					molecular_function											owl:Class	
GO:0010855	biolink:NamedThing	adenylate cyclase inhibitor activity	Decreases the activity of the enzyme that catalyzes the reaction: ATP = 3',5'-cyclic AMP + diphosphate.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0010854	biolink:NamedThing	adenylate cyclase regulator activity	Binds to and modulates the activity of the enzyme that catalyzes the reaction: ATP = 3',5'-cyclic AMP + diphosphate.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0015668	biolink:NamedThing	type III site-specific deoxyribonuclease activity	Catalysis of the endonucleolytic cleavage of DNA to give double-stranded fragments with terminal 5'-phosphates. ATP hydrolysis is required. Cleavage is dependent on the presence of two copies of a specific recognition sequence in an inverse orientation in the DNA. Cleavage occurs at a specific distance from one of the recognition sites.	tmpzr1t_l9r_go_relaxed.owl	type III restriction enzyme activity				MetaCyc:3.1.21.5-RXN|EC:3.1.21.5									molecular_function											owl:Class	
GO:0016888	biolink:NamedThing	endodeoxyribonuclease activity, producing 5'-phosphomonoesters	Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acids by creating internal breaks to yield 5'-phosphomonoesters.	tmpzr1t_l9r_go_relaxed.owl	endodeoxyribonuclease activity, producing 5' phosphomonoesters				Reactome:R-HSA-912368|EC:3.1.21.-									molecular_function											owl:Class	
GO:0010008	biolink:NamedThing	endosome membrane	The lipid bilayer surrounding an endosome.	tmpzr1t_l9r_go_relaxed.owl	endosomal membrane				NIF_Subcellular:sao978443756									cellular_component											owl:Class	
GO:2000437	biolink:NamedThing	regulation of monocyte extravasation	Any process that modulates the frequency, rate or extent of monocyte extravasation.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-03-04T10:24:08Z					biological_process											owl:Class	
GO:0002691	biolink:NamedThing	regulation of cellular extravasation	Any process that modulates the frequency, rate, or extent of cellular extravasation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0099181	biolink:NamedThing	structural constituent of presynapse	The action of a molecule that contributes to the structural integrity of a presynapse.	tmpzr1t_l9r_go_relaxed.owl								dos	2017-12-20T13:42:46Z					molecular_function											owl:Class	
GO:0098918	biolink:NamedThing	structural constituent of synapse	The action of a molecule that contributes to the structural integrity of a synapse.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1904044	biolink:NamedThing	response to aldosterone	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an aldosterone stimulus.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-03-16T23:07:53Z					biological_process											owl:Class	
GO:0102541	biolink:NamedThing	D-galactose 6-phosphate 1-epimerase activity	Catalysis of the reaction: alpha-D-galactose 6-phosphate = beta-D-galactose 6-phosphate.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-14816									molecular_function											owl:Class	
GO:0016857	biolink:NamedThing	racemase and epimerase activity, acting on carbohydrates and derivatives	Catalysis of a reaction that alters the configuration of one or more chiral centers in a carbohydrate molecule.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-6787677|EC:5.1.3.-									molecular_function											owl:Class	
GO:0014042	biolink:NamedThing	positive regulation of neuron maturation	Any process that activates or increases the frequency, rate or extent of neuron maturation.	tmpzr1t_l9r_go_relaxed.owl	upregulation of neuron maturation|stimulation of neuron maturation|up-regulation of neuron maturation|activation of neuron maturation|up regulation of neuron maturation													biological_process											owl:Class	
GO:0090498	biolink:NamedThing	extrinsic component of Golgi membrane	The component of a Golgi membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.	tmpzr1t_l9r_go_relaxed.owl	extrinsic to Golgi membrane							tb	2012-10-18T14:12:48Z					cellular_component											owl:Class	
GO:1903303	biolink:NamedThing	negative regulation of pyruvate kinase activity	Any process that stops, prevents or reduces the frequency, rate or extent of pyruvate kinase activity.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of pyruvate kinase activity|down-regulation of phosphoenol transphosphorylase activity|down regulation of phosphoenol transphosphorylase activity|downregulation of ATP:pyruvate 2-O-phosphotransferase activity|negative regulation of ATP:pyruvate 2-O-phosphotransferase activity|inhibition of ATP:pyruvate 2-O-phosphotransferase activity|inhibition of pyruvate kinase activity|downregulation of phosphoenol transphosphorylase activity|down regulation of ATP:pyruvate 2-O-phosphotransferase activity|down regulation of phosphoenolpyruvate kinase activity|downregulation of pyruvate kinase activity|down regulation of pyruvate kinase activity|down-regulation of phosphoenolpyruvate kinase activity|negative regulation of phosphoenol transphosphorylase activity|downregulation of phosphoenolpyruvate kinase activity|inhibition of phosphoenol transphosphorylase activity|inhibition of phosphoenolpyruvate kinase activity|negative regulation of phosphoenolpyruvate kinase activity|down-regulation of ATP:pyruvate 2-O-phosphotransferase activity							mr	2014-08-15T23:25:58Z					biological_process											owl:Class	
GO:1903302	biolink:NamedThing	regulation of pyruvate kinase activity	Any process that modulates the frequency, rate or extent of pyruvate kinase activity.	tmpzr1t_l9r_go_relaxed.owl	regulation of ATP:pyruvate 2-O-phosphotransferase activity|regulation of phosphoenol transphosphorylase activity|regulation of phosphoenolpyruvate kinase activity							mr	2014-08-15T23:25:51Z					biological_process											owl:Class	
GO:1902313	biolink:NamedThing	positive regulation of copper ion transmembrane transport	Any process that activates or increases the frequency, rate or extent of copper ion transmembrane transport.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of copper ion transmembrane transport|upregulation of copper ion transmembrane transport|positive regulation of copper ion membrane transport|activation of copper cation transmembrane transport|positive regulation of copper cation transmembrane transport|up regulation of copper ion membrane transport|activation of copper ion transmembrane transport|up regulation of copper ion transmembrane transport|upregulation of copper ion membrane transport|upregulation of copper cation transmembrane transport|up-regulation of copper ion membrane transport|up regulation of copper cation transmembrane transport|activation of copper ion membrane transport|up-regulation of copper cation transmembrane transport							di	2013-07-19T20:59:45Z					biological_process											owl:Class	
GO:1902311	biolink:NamedThing	regulation of copper ion transmembrane transport	Any process that modulates the frequency, rate or extent of copper ion transmembrane transport.	tmpzr1t_l9r_go_relaxed.owl	regulation of copper ion membrane transport|regulation of copper cation transmembrane transport							di	2013-07-19T20:59:28Z					biological_process											owl:Class	
GO:0002627	biolink:NamedThing	positive regulation of T cell antigen processing and presentation	Any process that activates or increases the frequency, rate, or extent of T cell antigen processing and presentation.	tmpzr1t_l9r_go_relaxed.owl	up regulation of T cell antigen processing and presentation|positive regulation of T-cell antigen processing and presentation|upregulation of T cell antigen processing and presentation|positive regulation of T-lymphocyte antigen processing and presentation|up-regulation of T cell antigen processing and presentation|positive regulation of T lymphocyte antigen processing and presentation|activation of T cell antigen processing and presentation|stimulation of T cell antigen processing and presentation													biological_process											owl:Class	
GO:0002625	biolink:NamedThing	regulation of T cell antigen processing and presentation	Any process that modulates the frequency, rate, or extent of T cell antigen processing and presentation.	tmpzr1t_l9r_go_relaxed.owl	regulation of T-cell antigen processing and presentation|regulation of T lymphocyte antigen processing and presentation|regulation of T-lymphocyte antigen processing and presentation													biological_process											owl:Class	
GO:0002667	biolink:NamedThing	regulation of T cell anergy	Any process that modulates the frequency, rate, or extent of T cell anergy.	tmpzr1t_l9r_go_relaxed.owl	regulation of T lymphocyte anergy|regulation of T-lymphocyte anergy|regulation of T-cell anergy													biological_process											owl:Class	
GO:0002911	biolink:NamedThing	regulation of lymphocyte anergy	Any process that modulates the frequency, rate, or extent of lymphocyte anergy.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0102551	biolink:NamedThing	homogentisate geranylgeranyl transferase activity	Catalysis of the reaction: 2-trans,6-trans,10-trans-geranylgeranyl diphosphate + homogentisate + H+ <=> diphosphoric acid + 2-methyl-6-geranylgeranyl-1,4-benzoquinol + carbon dioxide.	tmpzr1t_l9r_go_relaxed.owl					RHEA:38003|EC:2.5.1.116|MetaCyc:RXN-14929									molecular_function											owl:Class	
GO:0035150	biolink:NamedThing	regulation of tube size	Ensuring that a tube is of the correct length and diameter. Tube size must be maintained not only during tube formation, but also throughout development and in some physiological processes.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0090066	biolink:NamedThing	regulation of anatomical structure size	Any process that modulates the size of an anatomical structure.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-09-02T11:00:08Z					biological_process											owl:Class	
GO:0051951	biolink:NamedThing	positive regulation of glutamate uptake involved in transmission of nerve impulse	Any process that activates, maintains or increases the frequency, rate or extent of the directed movement of L-glutamate into a neuron or glial cell.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of glutamate uptake during transmission of nerve impulse|up-regulation of glutamate uptake during transmission of nerve impulse|positive regulation of glutamate reuptake|upregulation of glutamate uptake during transmission of nerve impulse|positive regulation of glutamate uptake involved in conduction of nerve impulse|activation of glutamate uptake during transmission of nerve impulse|stimulation of glutamate uptake during transmission of nerve impulse|up regulation of glutamate uptake during transmission of nerve impulse													biological_process											owl:Class	
GO:0002038	biolink:NamedThing	positive regulation of L-glutamate import across plasma membrane	Any process that activates or increases the frequency, rate or extent of L-glutamate import into a cell.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of L-glutamate uptake|upregulation of L-glutamate transport|up regulation of L-glutamate transport|activation of L-glutamate import|up-regulation of L-glutamate transport|upregulation of L-glutamate uptake|positive regulation of L-glutamate import|up regulation of L-glutamate import|upregulation of L-glutamate import|activation of L-glutamate transport|activation of L-glutamate uptake|up regulation of L-glutamate uptake|positive regulation of L-glutamate transport|up-regulation of L-glutamate import|up-regulation of L-glutamate uptake|stimulation of L-glutamate transport							al	2012-06-13T07:34:38Z			GO:1900922		biological_process											owl:Class	
GO:0031123	biolink:NamedThing	RNA 3'-end processing	Any process involved in forming the mature 3' end of an RNA molecule.	tmpzr1t_l9r_go_relaxed.owl	RNA 3' end processing													biological_process											owl:Class	
GO:0008194	biolink:NamedThing	UDP-glycosyltransferase activity	Catalysis of the transfer of a glycosyl group from a UDP-sugar to a small hydrophobic molecule.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-162730									molecular_function											owl:Class	
GO:0016757	biolink:NamedThing	glycosyltransferase activity	Catalysis of the transfer of a glycosyl group from one compound (donor) to another (acceptor).	tmpzr1t_l9r_go_relaxed.owl	transglycosylase activity|transferase activity, transferring glycosyl groups|transferase activity, transferring other glycosyl groups|transglycosidase activity				Reactome:R-HSA-5173005|EC:2.4.-.-|Reactome:R-HSA-6785565							GO:0016932		molecular_function											owl:Class	
GO:0050843	biolink:NamedThing	S-adenosylmethionine catabolic process	The chemical reactions and pathways resulting in the breakdown of S-adenosylmethionine, S-(5'-adenosyl)-L-methionine, an important intermediate in one-carbon metabolism.	tmpzr1t_l9r_go_relaxed.owl	SAM catabolic process|S-adenosyl methionine catabolic process|S-adenosylmethionine degradation|S-adenosylmethionine catabolism|S-adenosyl methionine catabolism|S-adenosylmethionine breakdown													biological_process											owl:Class	
GO:0061280	biolink:NamedThing	epithelial cell migration involved in mesonephric proximal tubule morphogenesis	The orderly movement of epithelial cells within a renal tubule that contributes to mesonephric proximal tubule morphogenesis.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-09-02T01:23:43Z					biological_process											owl:Class	
GO:0061278	biolink:NamedThing	epithelial cell migration involved in mesonephric nephron tubule morphogenesis	The orderly movement of epithelial cells within a renal tubule that contributes to mesonephric nephron tubule morphogenesis.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-09-02T01:18:53Z					biological_process											owl:Class	
GO:0071319	biolink:NamedThing	cellular response to benzoic acid	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a benzoic acid stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-12-10T05:10:20Z					biological_process											owl:Class	
GO:1900669	biolink:NamedThing	positive regulation of endocrocin biosynthetic process	Any process that activates or increases the frequency, rate or extent of endocrocin biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	up regulation of endocrocin biosynthesis|activation of endocrocin anabolism|up-regulation of endocrocin biosynthetic process|up regulation of endocrocin biosynthetic process|positive regulation of endocrocin biosynthesis|activation of endocrocin biosynthetic process|upregulation of endocrocin formation|positive regulation of endocrocin synthesis|upregulation of endocrocin biosynthesis|positive regulation of endocrocin formation|up regulation of endocrocin synthesis|up regulation of endocrocin anabolism|up-regulation of endocrocin synthesis|up regulation of endocrocin formation|upregulation of endocrocin synthesis|activation of endocrocin synthesis|activation of endocrocin formation|up-regulation of endocrocin biosynthesis|upregulation of endocrocin biosynthetic process|up-regulation of endocrocin anabolism|positive regulation of endocrocin anabolism|activation of endocrocin biosynthesis|upregulation of endocrocin anabolism|up-regulation of endocrocin formation							di	2012-05-22T04:16:35Z					biological_process											owl:Class	
GO:0034418	biolink:NamedThing	urate biosynthetic process	The chemical reactions and pathways resulting in the formation of urate, the anion of uric acid, 2,6,8-trioxypurine.	tmpzr1t_l9r_go_relaxed.owl	urate synthesis|urate anabolism|urate biosynthesis|uric acid biosynthetic process|urate formation													biological_process											owl:Class	
GO:0032987	biolink:NamedThing	protein-lipid complex disassembly	The disaggregation of a protein-lipid complex into its constituent components.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0071825	biolink:NamedThing	protein-lipid complex subunit organization	Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a protein-lipid complex.	tmpzr1t_l9r_go_relaxed.owl	protein-lipid complex subunit organisation							mah	2010-09-08T10:04:36Z					biological_process											owl:Class	
GO:0042824	biolink:NamedThing	MHC class I peptide loading complex	A large, multisubunit complex which consists of the MHC class I-beta 2 microglobulin dimer, the transporter associated with antigen presentation (TAP), tapasin (an MHC-encoded membrane protein), the chaperone calreticulin and the thiol oxidoreductase ERp57. Functions in the assembly of peptides with newly synthesized MHC class I molecules.	tmpzr1t_l9r_go_relaxed.owl	peptide-loading complex|PLC					Note that although this complex is located in the endoplasmic reticulum, there is some evidence that it may also be found in the Golgi.								cellular_component											owl:Class	
GO:0099569	biolink:NamedThing	presynaptic cytoskeleton	The portion of the cytoskeleton contained within the presynapse.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0005856	biolink:NamedThing	cytoskeleton	Any of the various filamentous elements that form the internal framework of cells, and typically remain after treatment of the cells with mild detergent to remove membrane constituents and soluble components of the cytoplasm. The term embraces intermediate filaments, microfilaments, microtubules, the microtrabecular lattice, and other structures characterized by a polymeric filamentous nature and long-range order within the cell. The various elements of the cytoskeleton not only serve in the maintenance of cellular shape but also have roles in other cellular functions, including cellular movement, cell division, endocytosis, and movement of organelles.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Cytoskeleton									cellular_component											owl:Class	
GO:0050602	biolink:NamedThing	monoprenyl isoflavone epoxidase activity	Catalysis of the reaction: O2 + NADPH + H+ + 7-O-methylluteone = H2O + NADP+ + dihydrofurano derivatives.	tmpzr1t_l9r_go_relaxed.owl	monoprenyl isoflavone monooxygenase activity|7-O-methylluteone,NADPH:O2 oxidoreductase activity|7-O-methylluteone:O2 oxidoreductase activity				EC:1.14.99.34|MetaCyc:1.14.99.34-RXN									molecular_function											owl:Class	
GO:0007063	biolink:NamedThing	regulation of sister chromatid cohesion	Any process that modulates the frequency, rate or extent of sister chromatid cohesion.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0090055	biolink:NamedThing	positive regulation of silent mating-type cassette heterochromatin assembly	Any process that increases the frequency, rate, or extent of chromatin silencing at silent mating-type cassette. Chromatin silencing at silent mating-type cassette is the repression of transcription at silent mating-type loci by altering the structure of chromatin.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of chromatin silencing at silent mating-type cassette	https://github.com/geneontology/go-ontology/issues/19112						tb	2009-08-07T10:54:36Z					biological_process											owl:Class	
GO:0090054	biolink:NamedThing	regulation of silent mating-type cassette heterochromatin assembly	Any process that modulates the frequency, rate, or extent of chromatin silencing at silent mating-type cassette. Chromatin silencing at silent mating-type cassette is the repression of transcription at silent mating-type loci by altering the structure of chromatin.	tmpzr1t_l9r_go_relaxed.owl	regulation of chromatin silencing at silent mating-type cassette	https://github.com/geneontology/go-ontology/issues/19112						tb	2009-08-07T10:52:59Z					biological_process											owl:Class	
GO:1904048	biolink:NamedThing	regulation of spontaneous neurotransmitter secretion	Any process that modulates the frequency, rate or extent of spontaneous neurotransmitter secretion.	tmpzr1t_l9r_go_relaxed.owl	regulation of stimulus-independent neurotransmitter secretion					An example of this is PARK2 / parkin in human (O60260) in PMID:22314364 (inferred from mutant phenotype).		pad	2015-03-17T10:37:11Z					biological_process											owl:Class	
GO:0046928	biolink:NamedThing	regulation of neurotransmitter secretion	Any process that modulates the frequency, rate or extent of the regulated release of a neurotransmitter from a cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:2001302	biolink:NamedThing	lipoxin A4 metabolic process	The chemical reactions and pathways involving lipoxin A4. Lipoxin A4 is a C20 hydroxy fatty acid having (5S)-, (6R)- and (15S)-hydroxy groups as well as (7E)- (9E)-, (11Z)- and (13E)-double bonds.	tmpzr1t_l9r_go_relaxed.owl	LXA4 metabolic process|LXA4 metabolism|lipoxin A4 metabolism							bf	2012-03-07T11:13:12Z					biological_process											owl:Class	
GO:0044023	biolink:NamedThing	histone kinase activity (H4-S1 specific)	Catalysis of the transfer of a phosphate group to the serine-1 residue of the N-terminal tail of histone H4.	tmpzr1t_l9r_go_relaxed.owl	histone serine kinase activity (H4-S1 specific)|histone-serine kinase activity (H4-S1 specific)													molecular_function											owl:Class	
GO:0035174	biolink:NamedThing	histone serine kinase activity	Catalysis of the transfer of a phosphate group to a serine residue of a histone. Histones are any of a group of water-soluble proteins found in association with the DNA of eukaroytic  chromosomes.	tmpzr1t_l9r_go_relaxed.owl	histone-serine kinase activity													molecular_function											owl:Class	
GO:0070014	biolink:NamedThing	sucrase-isomaltase complex	A protein complex that possesses oligo-1,6-glucosidase activity; the complex is a heterodimer located in the cell membrane, and is formed by proteolytic cleavage of a single precursor polypeptide. The two subunits have different substrate specificities.	tmpzr1t_l9r_go_relaxed.owl	oligo-1,6-glucosidase complex				Wikipedia:Sucrase-isomaltase									cellular_component											owl:Class	
GO:1902687	biolink:NamedThing	glucosidase complex	A protein complex which is capable of glucosidase activity.	tmpzr1t_l9r_go_relaxed.owl						An example of this is ygjK in E. coli (P42592) in PMID:23826932.		bhm	2014-02-12T10:55:10Z					cellular_component											owl:Class	
GO:0140448	biolink:NamedThing	signaling receptor ligand precursor processing	The cleavage of a peptide bond in a precursor form of a signaling receptor ligand, resulting in the mature (active) form of the ligand.	tmpzr1t_l9r_go_relaxed.owl	ligand maturation|signal maturation	https://github.com/geneontology/go-ontology/issues/19216						pg	2020-04-03T13:30:04Z			GO:0035638		biological_process											owl:Class	
GO:0048295	biolink:NamedThing	positive regulation of isotype switching to IgE isotypes	Any process that activates or increases the frequency, rate or extent of isotype switching to IgE isotypes.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of class switching to IgE isotypes|positive regulation of class switch recombination to IgE isotypes|stimulation of isotype switching to IgE isotypes|positive regulation of isotype switch recombination to IgE isotypes|up regulation of isotype switching to IgE isotypes|activation of isotype switching to IgE isotypes|up-regulation of isotype switching to IgE isotypes|upregulation of isotype switching to IgE isotypes													biological_process											owl:Class	
GO:0060353	biolink:NamedThing	regulation of cell adhesion molecule production	Any process that modulates the rate, frequency or extent of cell adhesion molecule production. Cell adhesion molecule production is the appearance of a cell adhesion molecule as a result of its biosynthesis or a decrease in its catabolism.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0048047	biolink:NamedThing	mating behavior, sex discrimination	The behavior of individuals for the purpose of discriminating between the sexes, for the purpose of finding a suitable mating partner.	tmpzr1t_l9r_go_relaxed.owl	mating behaviour, sex discrimination													biological_process											owl:Class	
GO:2001252	biolink:NamedThing	positive regulation of chromosome organization	Any process that activates or increases the frequency, rate or extent of chromosome organization.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of chromosome organisation|positive regulation of maintenance of genome integrity|positive regulation of nuclear genome maintenance|positive regulation of chromosome organization and biogenesis							yaf	2011-12-02T02:01:26Z					biological_process											owl:Class	
GO:0070857	biolink:NamedThing	regulation of bile acid biosynthetic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of bile acids.	tmpzr1t_l9r_go_relaxed.owl	regulation of bile acid anabolism|regulation of bile acid synthesis|regulation of bile acid biosynthesis|regulation of bile acid formation							mah	2009-08-14T03:09:02Z					biological_process											owl:Class	
GO:0010112	biolink:NamedThing	regulation of systemic acquired resistance	Any process that modulates the frequency, rate or extent of systemic acquired resistance.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0052747	biolink:NamedThing	sinapyl alcohol dehydrogenase activity	Catalysis of the reaction: sinapaldehyde + NADPH + H+ = sinapyl-alcohol + NADP+.	tmpzr1t_l9r_go_relaxed.owl	sinapyl-alcohol:NADP+ oxidoreductase activity|sinapyl-alcohol dehydrogenase activity				MetaCyc:RXN-1125|KEGG_REACTION:R03918|EC:1.1.1.195|RHEA:45704				2011-09-21T12:42:06Z					molecular_function											owl:Class	
GO:0018458	biolink:NamedThing	isopiperitenol dehydrogenase activity	Catalysis of the reaction: (1S,6R)-isopiperitenol + NAD(+) = (6R)-isoperitenone + H(+) + NADH.	tmpzr1t_l9r_go_relaxed.owl	(-)-trans-isopiperitenol:NAD+ oxidoreductase activity				MetaCyc:ISOPIPERITENOL-DEHYDROGENASE-RXN|KEGG_REACTION:R03261|RHEA:20860|EC:1.1.1.223|UM-BBD_reactionID:r0740									molecular_function											owl:Class	
GO:1901442	biolink:NamedThing	regulation of response to furfural	Any process that modulates the frequency, rate or extent of response to furfural.	tmpzr1t_l9r_go_relaxed.owl								tt	2012-10-02T14:09:26Z					biological_process											owl:Class	
GO:0048583	biolink:NamedThing	regulation of response to stimulus	Any process that modulates the frequency, rate or extent of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.	tmpzr1t_l9r_go_relaxed.owl						Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.								biological_process											owl:Class	
GO:0071384	biolink:NamedThing	cellular response to corticosteroid stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a corticosteroid hormone stimulus. A corticosteroid is a steroid hormone that is produced in the adrenal cortex. Corticosteroids are involved in a wide range of physiologic systems such as stress response, immune response and regulation of inflammation, carbohydrate metabolism, protein catabolism, blood electrolyte levels, and behavior. They include glucocorticoids and mineralocorticoids.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-12-11T03:52:07Z					biological_process											owl:Class	
GO:0071383	biolink:NamedThing	cellular response to steroid hormone stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a steroid hormone stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-12-11T03:49:02Z					biological_process											owl:Class	
GO:0002908	biolink:NamedThing	regulation of peripheral B cell deletion	Any process that modulates the frequency, rate, or extent of peripheral B cell deletion.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0002658	biolink:NamedThing	regulation of peripheral tolerance induction	Any process that modulates the frequency, rate, or extent of peripheral tolerance induction.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0106266	biolink:NamedThing	3-chloro THPH synthase activity	Catalysis of the reaction: 2,4,6-trihydroxyphenylhexan-1-one + chloride + FADH2 + O2 = (3-chloro-2,4,6-trihydroxyphenyl)hexan-1-one + FAD + H+ + 2 H2O.	tmpzr1t_l9r_go_relaxed.owl					RHEA:64356			hjd	2020-06-02T18:13:44Z					molecular_function											owl:Class	
GO:0000281	biolink:NamedThing	mitotic cytokinesis	A cell cycle process that results in the division of the cytoplasm of a cell after mitosis, resulting in the separation of the original cell into two daughter cells.	tmpzr1t_l9r_go_relaxed.owl	cytokinesis after mitosis													biological_process											owl:Class	
GO:0060521	biolink:NamedThing	mesenchymal-epithelial cell signaling involved in prostate induction	Signaling at short range from urogenital sinus mesenchymal cells to cells of the urogenital epithelium resulting in the epithelial cells adopting a prostatic fate.	tmpzr1t_l9r_go_relaxed.owl	mesenchymal-epithelial cell signalling involved in prostate induction													biological_process											owl:Class	
GO:0060522	biolink:NamedThing	inductive mesenchymal to epithelial cell signaling	Signaling at short range from mesenchymal cells to cells of an epithelium that results in a developmental change in the epithelial cells.	tmpzr1t_l9r_go_relaxed.owl	inductive mesenchymal to epithelial cell signalling													biological_process											owl:Class	
GO:1901099	biolink:NamedThing	negative regulation of signal transduction in absence of ligand	Any process that stops, prevents or reduces the frequency, rate or extent of signal transduction in absence of ligand.	tmpzr1t_l9r_go_relaxed.owl	down regulation of basal signaling|down-regulation of basal signaling|down regulation of signal transduction in absence of agonist|inhibition of signal transduction in absence of ligand|down-regulation of signal transduction in absence of ligand|down regulation of non-classical signal transduction|down-regulation of signal transduction in absence of agonist|downregulation of non-classical signal transduction|downregulation of basal signaling|down regulation of signal transduction in absence of ligand|downregulation of signal transduction in absence of agonist|downregulation of signal transduction in absence of ligand|negative regulation of non-classical signal transduction|down-regulation of non-classical signal transduction|negative regulation of signal transduction in absence of agonist							al	2012-07-10T10:31:08Z					biological_process											owl:Class	
GO:0071982	biolink:NamedThing	maintenance of diapause	The dormancy process that results an organism remaining in diapause. Diapause is a neurohormonally mediated, dynamic state of low metabolic activity. Associated characteristics of this form of dormancy include reduced morphogenesis, increased resistance to environmental extremes, and altered or reduced behavioral activity. Full expression develops in a species-specific manner, usually in response to a number of environmental stimuli that precede unfavorable conditions. Once diapause has begun, metabolic activity is suppressed even if conditions favorable for development prevail. Once initiated, only certain stimuli are capable of releasing the organism from this state, and this characteristic is essential in distinguishing diapause from hibernation.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-10-21T04:46:32Z					biological_process											owl:Class	
GO:0047224	biolink:NamedThing	acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity	Catalysis of the reaction: N-acetyl-D-galactosalaminyl-R + UDP-N-acetyl-D-glucosamine = N-acetyl-beta-D-glucosaminyl-1,3-N-acetyl-D-galactosaminyl-R + UDP.	tmpzr1t_l9r_go_relaxed.owl	mucin core 3 beta3-GlcNAc-transferase activity|core 3beta-GlcNAc-transferase activity|core 3-beta-GlcNAc-transferase activity|UDP-N-acetyl-D-glucosamine:O-glycosyl-glycoprotein (N-acetyl-D-glucosamine to N-acetyl-D-galactosaminyl-R) beta-1,3-N-acetyl-D-glucosaminyltransferase activity|O-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase III activity|uridine diphosphoacetylglucosamine-mucin beta(1->3)-acetylglucosaminyltransferase activity				MetaCyc:2.4.1.147-RXN|EC:2.4.1.147									molecular_function											owl:Class	
GO:0009294	biolink:NamedThing	DNA mediated transformation	The introduction and uptake of foreign genetic material (DNA or RNA) into a cell, and often the expression of that genetic material.	tmpzr1t_l9r_go_relaxed.owl	DNA-mediated transformation													biological_process											owl:Class	
GO:0009292	biolink:NamedThing	genetic transfer	In the absence of a sexual life cycle, the process involved in the introduction of genetic information to create a genetically different individual.	tmpzr1t_l9r_go_relaxed.owl	genetic exchange					GO:0009292 should not be used for annotation of phage lysogeny (integration of the bacteriophage nucleic acid into the host bacterium's genome).								biological_process											owl:Class	
GO:0003323	biolink:NamedThing	type B pancreatic cell development	The process whose specific outcome is the progression of a type B pancreatic cell over time, from its formation to the mature structure. A type B pancreatic cell is a cell located towards center of the islets of Langerhans that secretes insulin.	tmpzr1t_l9r_go_relaxed.owl	pancreatic B cell development|pancreatic beta cell development							dph	2009-11-02T08:20:11Z					biological_process											owl:Class	
GO:0016200	biolink:NamedThing	synaptic target attraction	The process in which a neuronal cell in a multicellular organism recognizes chemoattractant signals from, and grows towards, potential targets.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0050918	biolink:NamedThing	positive chemotaxis	The directed movement of a motile cell or organism towards a higher concentration of a chemical.	tmpzr1t_l9r_go_relaxed.owl	chemoattraction													biological_process											owl:Class	
GO:0047011	biolink:NamedThing	2-dehydropantolactone reductase (A-specific) activity	Catalysis of the reaction: (R)-pantolactone + NADP+ = 2-dehydropantolactone + NADPH + H+. The reaction is A-specific (i.e. the pro-R hydrogen is transferred from the 4-position of reduced nicotinamide cofactor) with respect to NADP+.	tmpzr1t_l9r_go_relaxed.owl	(R)-pantolactone:NADP+ oxidoreductase (A-specific)|2-oxopantoyl lactone reductase|2-ketopantoyl lactone reductase activity|2-dehydropantoyl-lactone reductase (A-specific) activity|ketopantoyl lactone reductase activity				MetaCyc:1.1.1.168-RXN|EC:1.1.1.168									molecular_function											owl:Class	
GO:0036441	biolink:NamedThing	2-dehydropantolactone reductase activity	Catalysis of the reaction: (R)-pantolactone + NADP+ = 2-dehydropantolactone + NADPH + H+.	tmpzr1t_l9r_go_relaxed.owl					RHEA:18981|KEGG_REACTION:R03155			bf	2013-09-30T16:26:27Z					molecular_function											owl:Class	
GO:2000477	biolink:NamedThing	regulation of metanephric glomerular visceral epithelial cell development	Any process that modulates the frequency, rate or extent of metanephric glomerular visceral epithelial cell development.	tmpzr1t_l9r_go_relaxed.owl	regulation of metanephric podocyte development							yaf	2011-03-09T05:16:40Z					biological_process											owl:Class	
GO:0060284	biolink:NamedThing	regulation of cell development	Any process that modulates the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0015495	biolink:NamedThing	gamma-aminobutyric acid:proton symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: gamma-aminobutyric acid(out) + H+(out) = gamma-aminobutyric acid(in) + H+(in).	tmpzr1t_l9r_go_relaxed.owl	gamma-aminobutyric acid:hydrogen symporter activity|4-aminobutanoate:hydrogen symporter activity|gamma-aminobutyric acid permease activity|4-aminobutyrate:proton symporter activity|4-aminobutanoate:proton symporter activity|GABA:hydrogen symporter activity|4-aminobutyrate:hydrogen symporter activity|GABA:proton symporter activity				Reactome:R-HSA-428625	See also the molecular function term 'neurotransmitter transporter activity ; GO:0005326'.						GO:0015329|GO:0005331		molecular_function											owl:Class	
GO:0015185	biolink:NamedThing	gamma-aminobutyric acid transmembrane transporter activity	Enables the transfer of gamma-aminobutyric acid from one side of a membrane to the other. Gamma-aminobutyric acid is 4-aminobutyrate (GABA).	tmpzr1t_l9r_go_relaxed.owl	GABA transporter activity|4-aminobutanoate transporter activity|betaine/GABA:sodium symporter activity|4-aminobutyrate transporter activity													molecular_function											owl:Class	
GO:0072147	biolink:NamedThing	glomerular parietal epithelial cell fate commitment	The process in which the developmental fate of a cell becomes restricted such that it will develop into a glomerular parietal epithelial cell. Glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. These cells may also give rise to podocytes.	tmpzr1t_l9r_go_relaxed.owl	Bowman's capsule cell fate commitment							mah	2010-02-24T02:00:52Z					biological_process											owl:Class	
GO:0019636	biolink:NamedThing	phosphonoacetate metabolic process	The chemical reactions and pathways involving phosphonoacetate, C2H4PO5, a substance composed of an acetate and a phosphonic acid residue.	tmpzr1t_l9r_go_relaxed.owl	phosphonoacetate metabolism				MetaCyc:P483-PWY									biological_process											owl:Class	
GO:0031582	biolink:NamedThing	replication fork arrest at rDNA repeats	A process that impedes the progress of the DNA replication fork at natural replication fork pausing sites within the eukaryotic rDNA repeat spacer.	tmpzr1t_l9r_go_relaxed.owl	replication fork blocking at rDNA repeats|replication fork arrest at ribosomal DNA repeats													biological_process											owl:Class	
GO:0043007	biolink:NamedThing	maintenance of rDNA	Any process involved in sustaining the fidelity and copy number of rDNA repeats.	tmpzr1t_l9r_go_relaxed.owl	rDNA maintenance|ribosomal DNA maintenance													biological_process											owl:Class	
GO:0032111	biolink:NamedThing	activation of protein histidine kinase activity	Any process that initiates the activity of an inactive protein histidine kinase.	tmpzr1t_l9r_go_relaxed.owl	protein histidine kinase activator													biological_process											owl:Class	
GO:1900651	biolink:NamedThing	positive regulation of dehydroaustinol biosynthetic process	Any process that activates or increases the frequency, rate or extent of dehydroaustinol biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of dehydroaustinol biosynthesis|activation of dehydroaustinol biosynthesis|activation of dehydroaustinol biosynthetic process|up regulation of dehydroaustinol formation|activation of dehydroaustinol formation|up regulation of dehydroaustinol synthesis|up-regulation of dehydroaustinol formation|positive regulation of dehydroaustinol synthesis|upregulation of dehydroaustinol formation|upregulation of dehydroaustinol biosynthesis|positive regulation of dehydroaustinol formation|up regulation of dehydroaustinol biosynthesis|up-regulation of dehydroaustinol biosynthesis|activation of dehydroaustinol synthesis|up regulation of dehydroaustinol anabolism|activation of dehydroaustinol anabolism|up-regulation of dehydroaustinol synthesis|upregulation of dehydroaustinol biosynthetic process|upregulation of dehydroaustinol synthesis|up-regulation of dehydroaustinol anabolism|upregulation of dehydroaustinol anabolism|up-regulation of dehydroaustinol biosynthetic process|up regulation of dehydroaustinol biosynthetic process|positive regulation of dehydroaustinol anabolism							di	2012-05-22T04:06:30Z					biological_process											owl:Class	
GO:1900649	biolink:NamedThing	regulation of dehydroaustinol biosynthetic process	Any process that modulates the frequency, rate or extent of dehydroaustinol biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of dehydroaustinol biosynthesis|regulation of dehydroaustinol formation|regulation of dehydroaustinol synthesis|regulation of dehydroaustinol anabolism							di	2012-05-22T04:06:03Z					biological_process											owl:Class	
GO:0046556	biolink:NamedThing	alpha-L-arabinofuranosidase activity	Catalysis of the hydrolysis of terminal non-reducing alpha-L-arabinofuranoside residues in alpha-L-arabinosides.	tmpzr1t_l9r_go_relaxed.owl	alpha-L-arabinofuranoside arabinofuranohydrolase activity|alpha-L-arabinofuranoside hydrolase activity|L-arabinosidase activity|alpha-L-arabinanase activity|polysaccharide alpha-L-arabinofuranosidase activity|arabinosidase activity|arabinofuranosidase activity|alpha-N-arabinofuranosidase activity|alpha-arabinofuranosidase activity|alpha-arabinosidase activity|alpha-L-arabinosidase activity				EC:3.2.1.55|MetaCyc:3.2.1.55-RXN									molecular_function											owl:Class	
GO:0071606	biolink:NamedThing	chemokine (C-C motif) ligand 4 production	The appearance of chemokine (C-C motif) ligand 4 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	tmpzr1t_l9r_go_relaxed.owl	macrophage inflammatory protein production|MIP-1b production|CCL4 production							mah	2010-02-05T04:16:42Z					biological_process											owl:Class	
GO:0032602	biolink:NamedThing	chemokine production	The appearance of a chemokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. All chemokines possess a number of conserved cysteine residues involved in intramolecular disulfide bond formation. Some chemokines are considered pro-inflammatory and can be induced during an immune response to recruit cells of the immune system to a site of infection, while others are considered homeostatic and are involved in controlling the migration of cells during normal processes of tissue maintenance or development. Chemokines are found in all vertebrates, some viruses and some bacteria.	tmpzr1t_l9r_go_relaxed.owl	chemokine secretion|chemokine metabolic process|chemokine synthesis|chemokine anabolism|chemokine biosynthesis|chemokine formation|chemokine biosynthetic process								2009-12-18T11:26:20Z			GO:0090195|GO:0050755|GO:0042033		biological_process											owl:Class	
GO:0043662	biolink:NamedThing	peribacteroid fluid	The soluble material inside the peribacteroid membrane, but outside of the bacteroid, within a bacteroid-containing symbiosome.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0003275	biolink:NamedThing	apoptotic process involved in outflow tract morphogenesis	Any apoptotic process that contributes to the shaping of the outflow tract. The outflow tract is the portion of the heart through which blood flows into the arteries.	tmpzr1t_l9r_go_relaxed.owl	apoptosis involved in outflow tract morphogenesis							dph	2009-10-20T09:30:01Z					biological_process											owl:Class	
GO:0006954	biolink:NamedThing	inflammatory response	The immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The process is characterized by local vasodilation, extravasation of plasma into intercellular spaces and accumulation of white blood cells and macrophages.	tmpzr1t_l9r_go_relaxed.owl	inflammation				Wikipedia:Inflammation									biological_process											owl:Class	
GO:0006952	biolink:NamedThing	defense response	Reactions, triggered in response to the presence of a foreign body or the occurrence of an injury, which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack.	tmpzr1t_l9r_go_relaxed.owl	defense/immunity protein activity|defence response|physiological defense response|antimicrobial peptide activity											GO:0042829|GO:0002217		biological_process											owl:Class	
GO:0090221	biolink:NamedThing	mitotic spindle-templated microtubule nucleation	The 'de novo' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates from within the mitotic spindle.	tmpzr1t_l9r_go_relaxed.owl								tb	2010-01-13T10:42:37Z					biological_process											owl:Class	
GO:0007020	biolink:NamedThing	microtubule nucleation	The process in which tubulin alpha-beta heterodimers begin aggregation to form an oligomeric tubulin structure (a microtubule seed). Microtubule nucleation is the initiating step in the formation of a microtubule in the absence of any existing microtubules ('de novo' microtubule formation).	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Microtubule_nucleation									biological_process											owl:Class	
GO:1903660	biolink:NamedThing	negative regulation of complement-dependent cytotoxicity	Any process that stops, prevents or reduces the frequency, rate or extent of complement-dependent cytotoxicity.	tmpzr1t_l9r_go_relaxed.owl	down regulation of complement-dependent cytotoxicity|inhibition of complement-dependent cytotoxicity|down-regulation of complement-dependent cytotoxicity|downregulation of complement-dependent cytotoxicity							jl	2014-11-25T15:04:02Z					biological_process											owl:Class	
GO:0031562	biolink:NamedThing	hyphal tip polarisome	Protein complex that has a role in determining cell polarity, found at the tip of a growing fungal hypha.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0000133	biolink:NamedThing	polarisome	Protein complex that plays a role in determining cell polarity by directing the localized assembly of actin filaments at polarization sites; in Saccharomyces the polarisome includes Bni1p, Spa2p, Pea2p, and Bud6p.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0043291	biolink:NamedThing	RAVE complex	A multisubunit complex that in Saccharomyces is composed of three subunits, Rav1p, Rav2p and Skp1p. Acts transiently to catalyze assembly of cytoplasmic V1, with membrane embedded V0 to form the V-ATPase holoenzyme.	tmpzr1t_l9r_go_relaxed.owl	regulator of the (H+)-ATPase of the vacuolar and endosomal membranes													cellular_component											owl:Class	
GO:1905544	biolink:NamedThing	L-methionine import across plasma membrane	The directed movement of L-methionine from outside of a cell, across the plasma membrane and into the cytosol.	tmpzr1t_l9r_go_relaxed.owl	L-methionine import into cell							mah	2015-01-16T15:03:17Z			GO:1903813		biological_process											owl:Class	
GO:1903692	biolink:NamedThing	methionine import across plasma membrane	The directed movement of methionine from outside of a cell, across the plasma membrane and into the cytosol.	tmpzr1t_l9r_go_relaxed.owl	methionine import|methionine import into cell							jl	2012-08-15T14:54:38Z			GO:0044690		biological_process											owl:Class	
GO:0010766	biolink:NamedThing	negative regulation of sodium ion transport	Any process that decreases the frequency, rate or extent of the directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0031305	biolink:NamedThing	integral component of mitochondrial inner membrane	The component of the mitochondrial inner membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.	tmpzr1t_l9r_go_relaxed.owl	integral to mitochondrial inner membrane													cellular_component											owl:Class	
GO:0031304	biolink:NamedThing	intrinsic component of mitochondrial inner membrane	The component of the mitochondrial inner membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.	tmpzr1t_l9r_go_relaxed.owl	intrinsic to mitochondrial inner membrane													cellular_component											owl:Class	
GO:0010923	biolink:NamedThing	negative regulation of phosphatase activity	Any process that decreases the rate or frequency of phosphatase activity. Phosphatases catalyze the hydrolysis of phosphoric monoesters, releasing inorganic phosphate.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0010921	biolink:NamedThing	regulation of phosphatase activity	Any process that modulates the rate or frequency of phosphatase activity. Phosphatases catalyze the hydrolysis of phosphoric monoesters, releasing inorganic phosphate.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0103059	biolink:NamedThing	UDP-L-rhamnose:kaempferol 3-O-rhamnosyltransferase activity	Catalysis of the reaction: kaempferol oxoanion + UDP-L-rhamnose <=> H+ + kaempferol-3-rhamnoside + UDP(3-).	tmpzr1t_l9r_go_relaxed.owl					RHEA:61164|MetaCyc:RXN1F-474									molecular_function											owl:Class	
GO:0015811	biolink:NamedThing	L-cystine transport	The directed movement of L-cystine (also known as dicysteine) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0036434	biolink:NamedThing	nitronate monooxygenase (FMN-linked) activity	Catalysis of the reaction: ethylnitronate + FMNH(2) + O(2) = acetaldehyde + FMN + H(2)O + H(+) + nitrite.	tmpzr1t_l9r_go_relaxed.owl					KEGG_REACTION:R00025|RHEA:26458			bf	2013-09-16T16:20:13Z					molecular_function											owl:Class	
GO:0070163	biolink:NamedThing	regulation of adiponectin secretion	Any process that modulates the frequency, rate or extent of the regulated release of adiponectin from a cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0050708	biolink:NamedThing	regulation of protein secretion	Any process that modulates the frequency, rate or extent of the controlled release of a protein from a cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0098556	biolink:NamedThing	cytoplasmic side of rough endoplasmic reticulum membrane	The side (leaflet) of the rough endoplasmic reticulum membrane that faces the cytoplasm.	tmpzr1t_l9r_go_relaxed.owl								dos	2013-12-03T12:15:44Z					cellular_component											owl:Class	
GO:0002064	biolink:NamedThing	epithelial cell development	The process whose specific outcome is the progression of an epithelial cell over time, from its formation to the mature structure. An epithelial cell is a cell usually found in a two-dimensional sheet with a free surface.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0019682	biolink:NamedThing	glyceraldehyde-3-phosphate metabolic process	The chemical reactions and pathways involving glyceraldehyde-3-phosphate, an important intermediate in glycolysis.	tmpzr1t_l9r_go_relaxed.owl	glyceraldehyde 3-phosphate metabolism|glyceraldehyde 3-phosphate metabolic process|glyceraldehyde-3-phosphate metabolism													biological_process											owl:Class	
GO:0042602	biolink:NamedThing	riboflavin reductase (NADPH) activity	Catalysis of the reaction: reduced riboflavin + NADP+ = riboflavin + NADPH + 2 H+.	tmpzr1t_l9r_go_relaxed.owl	FMN reductase (NADPH) activity|NADPH-riboflavin oxidoreductase activity|riboflavin mononucleotide (reduced nicotinamide adenine dinucleotide phosphate) reductase activity|flavin reductase activity|NADPH2 dehydrogenase (riboflavin)|NADPH-dependent FMN reductase activity|riboflavine mononucleotide reductase activity|NADPH-specific FMN reductase activity|NADPH-FMN reductase activity|reduced-riboflavin:NADP+ oxidoreductase activity|NADPH:riboflavin oxidoreductase activity|riboflavin mononucleotide reductase activity|NADPH-riboflavin reductase activity|NADPH dehydrogenase (riboflavin) activity|NADPH2:riboflavin oxidoreductase activity				RHEA:19377|EC:1.5.1.30|EC:1.5.1.41|MetaCyc:NADPH-DEHYDROGENASE-FLAVIN-RXN|KEGG_REACTION:R05707									molecular_function											owl:Class	
GO:0031788	biolink:NamedThing	motilin receptor binding	Binding to a motilin receptor.	tmpzr1t_l9r_go_relaxed.owl	motilin receptor ligand													molecular_function											owl:Class	
GO:0015650	biolink:NamedThing	lactate:proton symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: lactate (out) + H+ (out) = lactate (in) + H+ (in).	tmpzr1t_l9r_go_relaxed.owl	lactate:proton porter activity|lactate:hydrogen symporter activity|lactate:hydrogen porter activity|lactate permease													molecular_function											owl:Class	
GO:0019489	biolink:NamedThing	methylgallate metabolic process	The chemical reactions and pathways involving methylgallate, trihydroxymethylbenzoate, the anion of methylgallic acid.	tmpzr1t_l9r_go_relaxed.owl	methylgallate metabolism													biological_process											owl:Class	
GO:0009712	biolink:NamedThing	catechol-containing compound metabolic process	The chemical reactions and pathways involving a compound containing a pyrocatechol (1,2-benzenediol) nucleus or substituent.	tmpzr1t_l9r_go_relaxed.owl	catechol metabolic process|catechol metabolism													biological_process											owl:Class	
GO:0002020	biolink:NamedThing	protease binding	Binding to a protease or a peptidase.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-1297354									molecular_function											owl:Class	
GO:0008094	biolink:NamedThing	ATP-dependent activity, acting on DNA	Catalytic activity that acts to modify DNA, driven by ATP hydrolysis.	tmpzr1t_l9r_go_relaxed.owl	ATPase, acting on DNA|ATPase activity, acting on DNA|DNA dependent ATPase activity|DNA-dependent adenosinetriphosphatase activity|adenosinetriphosphatase (DNA-dependent)|DNA-dependent ATPase activity	https://github.com/geneontology/go-ontology/issues/21775|https://github.com/geneontology/go-ontology/issues/20876|https://github.com/geneontology/go-ontology/issues/21612										GO:0004011		molecular_function											owl:Class	
GO:0072332	biolink:NamedThing	intrinsic apoptotic signaling pathway by p53 class mediator	A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, and ends when the execution phase of apoptosis is triggered.	tmpzr1t_l9r_go_relaxed.owl	intrinsic apoptotic signaling pathway by signal transduction by p53 class mediator|signal transduction by p53 class mediator resulting in induction of apoptosis							mah	2010-11-03T01:47:56Z					biological_process											owl:Class	
GO:0097193	biolink:NamedThing	intrinsic apoptotic signaling pathway	A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway starts with reception of an intracellular signal (e.g. DNA damage, endoplasmic reticulum stress, oxidative stress etc.), and ends when the execution phase of apoptosis is triggered. The intrinsic apoptotic signaling pathway is crucially regulated by permeabilization of the mitochondrial outer membrane (MOMP).	tmpzr1t_l9r_go_relaxed.owl	induction of apoptosis by intracellular signals|intrinsic apoptotic signalling pathway|mitochondrial-mediated apoptotic pathway|intrinsic apoptosis|intrinsic apoptotic pathway					The signals that start intrinsic apoptosis may come from extracellular sources (e.g. oxidative stress, UV exposure), but the reception of the signal and thus the signaling pathway start inside the cell (as a result of DNA damage, redox imbalance, etc.). Examples are ZPR9 (ZNF622) and ASK1 (MAP3K5) (UniProt symbols Q969S3 and Q99683) in PMID:21771788. A diagram of the intrinsic apoptotic pathway including examples of molecular players can be found in Figure 2 in PMID:21760595.		pr	2011-11-23T09:40:50Z			GO:0008629		biological_process											owl:Class	
GO:0044147	biolink:NamedThing	negative regulation of formation of structure involved in a symbiotic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the progression of an organism from an initial condition to a later condition, occurring in, on or near the exterior of its host organism.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of development of symbiont involved in interaction with host|negative regulation of development of symbiont during interaction with host	https://github.com/geneontology/go-ontology/issues/20305				This term partially replaces the obsolete term 'negative regulation of growth or development of symbiont during interaction with host ; GO:0075340'.		jl	2009-08-06T02:04:59Z					biological_process											owl:Class	
GO:0044145	biolink:NamedThing	modulation of formation of structure involved in a symbiotic process	Any process that modulates the frequency, rate or extent of the progression of an organism from an initial condition to a later condition, occurring in, on or near the exterior of its host organism.	tmpzr1t_l9r_go_relaxed.owl	modulation of development of symbiont involved in interaction with host|modulation of development of symbiont during interaction with host	https://github.com/geneontology/go-ontology/issues/20305				This term partially replaces the obsolete term 'modulation of growth or development of symbiont during interaction with host ; GO:0075338'. See also 'modulation of growth of symbiont during interaction with host ; GO:0044144'.		jl	2009-08-06T01:57:38Z					biological_process											owl:Class	
GO:0042211	biolink:NamedThing	dimethylsilanediol catabolic process	The aerobic chemical reactions and pathways resulting in the breakdown of dimethylsilanediol, the smallest member of the dialkylsilanediols. Dimethylsilanediol is the monomer of polydimethylsiloxane, a compound which can be found in a wide range of industrial and consumer products.	tmpzr1t_l9r_go_relaxed.owl	catabolism of DMSD|catabolic process of DMSD|dimethylsilanediol degradation|dimethylsilanediol breakdown|dimethylsilanediol catabolism|degradation of dimethylsilanediol													biological_process											owl:Class	
GO:0018946	biolink:NamedThing	aerobic organosilicon metabolic process	The chemical reactions and pathways involving organosilicons, organic compounds that contain silicon, in the presence of oxygen.	tmpzr1t_l9r_go_relaxed.owl	aerobic organosilicone metabolism|aerobic organosilicon metabolism|aerobic organosilicone metabolic process				UM-BBD_pathwayID:osi									biological_process											owl:Class	
GO:1905456	biolink:NamedThing	regulation of lymphoid progenitor cell differentiation	Any process that modulates the frequency, rate or extent of lymphoid progenitor cell differentiation.	tmpzr1t_l9r_go_relaxed.owl								rz	2016-09-16T12:32:40Z					biological_process											owl:Class	
GO:0015182	biolink:NamedThing	L-asparagine transmembrane transporter activity	Enables the transfer of L-asparagine from one side of a membrane to the other. L-asparagine is the L-enantiomer of alpha-aminosuccinamic acid.	tmpzr1t_l9r_go_relaxed.owl	asparagine/glutamine permease activity|L-asparagine transporter activity													molecular_function											owl:Class	
GO:0003288	biolink:NamedThing	ventricular septum intermedium morphogenesis	The developmental process in which a ventricular septum intermedium is generated and organized.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-10-20T10:58:48Z					biological_process											owl:Class	
GO:0060412	biolink:NamedThing	ventricular septum morphogenesis	The developmental process in which a ventricular septum is generated and organized. A ventricular septum is an anatomical structure that separates the lower chambers (ventricles) of the heart from one another.	tmpzr1t_l9r_go_relaxed.owl	interventricular septum morphogenesis													biological_process											owl:Class	
GO:1904899	biolink:NamedThing	positive regulation of hepatic stellate cell proliferation	Any process that activates or increases the frequency, rate or extent of hepatic stellate cell proliferation.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of perisinusoidal cell proliferation|up regulation of hepatic perisinusoidal cell proliferation|up-regulation of perisinusoidal cell proliferation|up-regulation of hepatic stellate cell proliferation|activation of Ito cell proliferation|activation of hepatic perisinusoidal cell proliferation|upregulation of Ito cell proliferation|positive regulation of Ito cell proliferation|up regulation of Ito cell proliferation|upregulation of hepatic stellate cell proliferation|up-regulation of Ito cell proliferation|up regulation of hepatic stellate cell proliferation|upregulation of perisinusoidal cell proliferation|positive regulation of hepatic perisinusoidal cell proliferation|up regulation of perisinusoidal cell proliferation|activation of perisinusoidal cell proliferation|activation of hepatic stellate cell proliferation|up-regulation of hepatic perisinusoidal cell proliferation|upregulation of hepatic perisinusoidal cell proliferation							sl	2016-01-14T15:57:13Z					biological_process											owl:Class	
GO:0050354	biolink:NamedThing	triokinase activity	Catalysis of the reaction: D-glyceraldehyde + ATP = D-glyceraldehyde 3-phosphate + ADP + 2 H(+).	tmpzr1t_l9r_go_relaxed.owl	trio triose kinase (phosphorylating)|triose kinase activity|D-triokinase activity|ATP:D-glyceraldehyde 3-phosphotransferase activity				Reactome:R-HSA-70349|EC:2.7.1.28|KEGG_REACTION:R01059|MetaCyc:TRIOKINASE-RXN|RHEA:13941									molecular_function											owl:Class	
GO:1900646	biolink:NamedThing	regulation of chanoclavine-I aldehyde biosynthetic process	Any process that modulates the frequency, rate or extent of chanoclavine-I aldehyde biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of chanoclavine-I aldehyde biosynthesis|regulation of chanoclavine-I aldehyde synthesis|regulation of chanoclavine-I aldehyde formation|regulation of chanoclavine-I aldehyde anabolism							di	2012-05-22T04:04:38Z					biological_process											owl:Class	
GO:1900822	biolink:NamedThing	regulation of ergot alkaloid biosynthetic process	Any process that modulates the frequency, rate or extent of ergot alkaloid biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of ergot alkaloid synthesis|regulation of ergot alkaloid anabolism|regulation of ergot alkaloid formation|regulation of ergot alkaloid biosynthesis							di	2012-06-04T11:12:32Z					biological_process											owl:Class	
GO:1905815	biolink:NamedThing	regulation of dorsal/ventral axon guidance	Any process that modulates the frequency, rate or extent of dorsal/ventral axon guidance.	tmpzr1t_l9r_go_relaxed.owl	regulation of dorsoventral axon guidance|regulation of dorsal-ventral axon guidance|regulation of dorsal/ventral axon pathfinding							hbye	2017-01-12T13:38:44Z					biological_process											owl:Class	
GO:1902667	biolink:NamedThing	regulation of axon guidance	Any process that modulates the frequency, rate or extent of axon guidance.	tmpzr1t_l9r_go_relaxed.owl	regulation of axon growth cone guidance|regulation of axon chemotaxis|regulation of axon pathfinding							hjd	2014-01-31T18:50:10Z					biological_process											owl:Class	
GO:0003256	biolink:NamedThing	regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation	Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the differentiation of a myocardial precursor cell.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-10-15T01:01:25Z					biological_process											owl:Class	
GO:0098985	biolink:NamedThing	asymmetric, glutamatergic, excitatory synapse	A neuron to neuron synapse with a postsynaptic density, that uses glutamate as a neurotransmitter and whose activity results in excitatory postsynaptic potentials.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0032279	biolink:NamedThing	asymmetric synapse	A type of synapse occurring between an axon and a dendritic spine or dendritic shaft. Asymmetric synapses, the most abundant synapse type in the central nervous system, involve axons that contain predominantly spherical vesicles and contain a thickened postsynaptic density.  Most or all synapses of this type are excitatory.	tmpzr1t_l9r_go_relaxed.owl	Gray's type I synapse													cellular_component											owl:Class	
GO:0051643	biolink:NamedThing	endoplasmic reticulum localization	Any process in which endoplasmic reticulum is transported to, and/or maintained in, a specific location within the cell.	tmpzr1t_l9r_go_relaxed.owl	establishment and maintenance of ER localization|endoplasmic reticulum localisation|ER localization													biological_process											owl:Class	
GO:0051640	biolink:NamedThing	organelle localization	Any process in which an organelle is transported to, and/or maintained in, a specific location.	tmpzr1t_l9r_go_relaxed.owl	organelle localisation|establishment and maintenance of organelle localization													biological_process											owl:Class	
GO:0016054	biolink:NamedThing	organic acid catabolic process	The chemical reactions and pathways resulting in the breakdown of organic acids, any acidic compound containing carbon in covalent linkage.	tmpzr1t_l9r_go_relaxed.owl	organic acid degradation|organic acid catabolism|organic acid breakdown													biological_process											owl:Class	
GO:1901770	biolink:NamedThing	daunorubicin catabolic process	The chemical reactions and pathways resulting in the breakdown of daunorubicin.	tmpzr1t_l9r_go_relaxed.owl	daunorubicin catabolism|daunorubicin degradation|daunorubicin breakdown							yaf	2013-01-15T10:14:29Z					biological_process											owl:Class	
GO:1901662	biolink:NamedThing	quinone catabolic process	The chemical reactions and pathways resulting in the breakdown of quinone.	tmpzr1t_l9r_go_relaxed.owl	quinone cofactor catabolic process|quinone cofactor breakdown|quinone cofactor catabolism|quinone cofactor degradation|quinone degradation|quinone breakdown|quinone catabolism							pr	2012-11-20T14:44:44Z			GO:0042378		biological_process											owl:Class	
GO:0060514	biolink:NamedThing	prostate induction	The close range interaction of the urogenital sinus mesenchyme and the urogenital sinus epithelium that causes the cells of the urogenital sinus epithelium to change their fates and specify the development of the prostate gland.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1905332	biolink:NamedThing	positive regulation of morphogenesis of an epithelium	Any process that activates or increases the frequency, rate or extent of morphogenesis of an epithelium.	tmpzr1t_l9r_go_relaxed.owl	activation of epithelium morphogenesis|up regulation of morphogenesis of an epithelium|activation of morphogenesis of an epithelium|up regulation of epithelium morphogenesis|upregulation of morphogenesis of an epithelium|up-regulation of epithelium morphogenesis|positive regulation of epithelium morphogenesis|upregulation of epithelium morphogenesis|up-regulation of morphogenesis of an epithelium					An example of this is MMRN2 in human (Q9H8L6) in PMID:25745997 (inferred from direct assay).		bhm	2016-07-22T07:14:05Z					biological_process											owl:Class	
GO:0042983	biolink:NamedThing	amyloid precursor protein biosynthetic process	The chemical reactions and pathways resulting in the formation of amyloid precursor protein (APP), the precursor of amyloid-beta, a glycoprotein associated with Alzheimer's disease.	tmpzr1t_l9r_go_relaxed.owl	amyloid precursor protein synthesis|APP biosynthesis|amyloid precursor protein biosynthesis|APP biosynthetic process|amyloid precursor protein formation|amyloid precursor protein anabolism													biological_process											owl:Class	
GO:0042982	biolink:NamedThing	amyloid precursor protein metabolic process	The chemical reactions and pathways involving amyloid precursor protein (APP), the precursor of amyloid-beta, a glycoprotein associated with Alzheimer's disease.	tmpzr1t_l9r_go_relaxed.owl	APP metabolism|APP metabolic process|amyloid precursor protein metabolism													biological_process											owl:Class	
GO:0004474	biolink:NamedThing	malate synthase activity	Catalysis of the reaction: acetyl-CoA + glyoxylate + H(2)O = (S)-malate + CoA + H(+).	tmpzr1t_l9r_go_relaxed.owl	L-malate glyoxylate-lyase (CoA-acetylating) activity|malic-condensing enzyme activity|acetyl-CoA:glyoxylate C-acetyltransferase (thioester-hydrolysing, carboxymethyl-forming)|malate synthetase activity|glyoxylic transacetase activity|glyoxylate transacetase activity|malic synthetase activity|malate condensing enzyme activity|glyoxylate transacetylase activity				EC:2.3.3.9|RHEA:18181|KEGG_REACTION:R00472|MetaCyc:MALSYN-RXN	Note that this function was formerly EC:4.1.3.2.								molecular_function											owl:Class	
GO:0046642	biolink:NamedThing	negative regulation of alpha-beta T cell proliferation	Any process that stops, prevents, or reduces the frequency, rate or extent of alpha-beta T cell proliferation.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of alpha-beta T cell proliferation|down regulation of alpha-beta T cell proliferation|inhibition of alpha-beta T cell proliferation|negative regulation of alpha-beta T lymphocyte proliferation|negative regulation of alpha-beta T-cell proliferation|negative regulation of alpha-beta T-lymphocyte proliferation|downregulation of alpha-beta T cell proliferation													biological_process											owl:Class	
GO:0007118	biolink:NamedThing	budding cell apical bud growth	Growth at the tip of a bud, in a cell that reproduces by budding.	tmpzr1t_l9r_go_relaxed.owl	apical bud growth													biological_process											owl:Class	
GO:0007117	biolink:NamedThing	budding cell bud growth	The process in which the bud portion of a cell that reproduces by budding irreversibly increases in size over time by accretion and biosynthetic production of matter similar to that already present.	tmpzr1t_l9r_go_relaxed.owl	bud growth													biological_process											owl:Class	
GO:1904635	biolink:NamedThing	positive regulation of glomerular visceral epithelial cell apoptotic process	Any process that activates or increases the frequency, rate or extent of glomerular visceral epithelial cell apoptotic process.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of glomerular visceral epithelial cell apoptotic process|up regulation of podocyte apoptotic process|upregulation of glomerular visceral epithelial cell apoptotic process|positive regulation of glomerular visceral epithelial cell apoptosis|activation of podocyte apoptotic process|up-regulation of glomerular podocyte apoptosis|up regulation of glomerular visceral epithelial cell apoptotic process|up-regulation of glomerular podocyte apoptotic process|positive regulation of glomerular podocyte apoptosis|up-regulation of glomerular visceral epithelial cell apoptosis|upregulation of glomerular podocyte apoptotic process|up regulation of podocyte apoptosis|activation of glomerular podocyte apoptosis|activation of glomerular podocyte apoptotic process|activation of podocyte apoptosis|positive regulation of podocyte apoptosis|up-regulation of podocyte apoptotic process|upregulation of podocyte apoptotic process|up regulation of glomerular podocyte apoptosis|up regulation of glomerular podocyte apoptotic process|activation of glomerular visceral epithelial cell apoptosis|upregulation of podocyte apoptosis|up regulation of glomerular visceral epithelial cell apoptosis|positive regulation of glomerular podocyte apoptotic process|activation of glomerular visceral epithelial cell apoptotic process|up-regulation of podocyte apoptosis|upregulation of glomerular podocyte apoptosis|positive regulation of podocyte apoptotic process|upregulation of glomerular visceral epithelial cell apoptosis							sl	2015-08-28T14:14:56Z					biological_process											owl:Class	
GO:0042675	biolink:NamedThing	compound eye cone cell differentiation	The process in which a relatively unspecialized cell acquires the specialized features of a compound eye cone cell, a cone-shaped cell, that focuses light in a compound eye.	tmpzr1t_l9r_go_relaxed.owl												GO:0042674		biological_process											owl:Class	
GO:0034943	biolink:NamedThing	trans-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity	Catalysis of the reaction: trans-2-methyl-5-isopropylhexa-2,5-dienoic acid + ATP + CoASH = trans-2-methyl-5-isopropylhexa-2,5-dienoyl-CoA + AMP + PPi.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0989									molecular_function											owl:Class	
GO:0047844	biolink:NamedThing	deoxycytidine deaminase activity	Catalysis of the reaction: deoxycytidine + H2O = deoxyuridine + NH3.	tmpzr1t_l9r_go_relaxed.owl	deoxycytidine aminohydrolase activity				RHEA:13433|MetaCyc:CYTIDEAM-RXN|EC:3.5.4.14									molecular_function											owl:Class	
GO:0002816	biolink:NamedThing	regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria	Any process that modulates the frequency, rate, or extent of biosynthesis of antibacterial peptides active against Gram-positive bacteria.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0031309	biolink:NamedThing	integral component of nuclear outer membrane	The component of the nuclear outer membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.	tmpzr1t_l9r_go_relaxed.owl	integral to nuclear outer membrane													cellular_component											owl:Class	
GO:2000310	biolink:NamedThing	regulation of NMDA receptor activity	Any process that modulates the frequency, rate or extent of N-methyl-D-aspartate selective glutamate receptor activity.	tmpzr1t_l9r_go_relaxed.owl	regulation of N-methyl-D-aspartate selective glutamate receptor activity							bf	2011-01-18T10:06:37Z					biological_process											owl:Class	
GO:0017089	biolink:NamedThing	glycolipid transfer activity	Removes a glycolipid from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle. A glycolipid is a compound usually containing 1-4 linked monosaccharide residues joined by a glycosyl linkage to a lipid.	tmpzr1t_l9r_go_relaxed.owl	glycolipid carrier activity|intermembrane glycolipid transfer activity|glycolipid transporter activity|intermembrane glycolipid transporter activity				Reactome:R-HSA-5340320|Reactome:R-HSA-9697077									molecular_function											owl:Class	
GO:0007565	biolink:NamedThing	female pregnancy	The set of physiological processes that allow an embryo or foetus to develop within the body of a female animal. It covers the time from fertilization of a female ovum by a male spermatozoon until birth.	tmpzr1t_l9r_go_relaxed.owl	carrying of young|gestation				Wikipedia:Gestation									biological_process											owl:Class	
GO:0010431	biolink:NamedThing	seed maturation	A process in seed development that occurs after embryogenesis by which a quiescent state is established in a seed. Seed maturation is characterized by storage compound accumulation, acquisition of desiccation tolerance, growth arrest and the entry into a dormancy period of variable length that is broken upon germination.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0042043	biolink:NamedThing	neurexin family protein binding	Binding to a neurexin, a synaptic cell surface protein related to latrotoxin receptor, laminin and agrin. Neurexins act as cell recognition molecules at nerve terminals.	tmpzr1t_l9r_go_relaxed.owl	neuroligin											GO:0019963		molecular_function											owl:Class	
GO:0099518	biolink:NamedThing	vesicle cytoskeletal trafficking	The directed movement of a vesicle along a cytoskeletal fiber such as a microtubule or and actin filament, mediated by motor proteins.	tmpzr1t_l9r_go_relaxed.owl	cytoskeletal fiber-based vesicle localization|vesicle cytoskeletal transport													biological_process											owl:Class	
GO:0030705	biolink:NamedThing	cytoskeleton-dependent intracellular transport	The directed movement of substances along cytoskeletal fibers such as microfilaments or microtubules within a cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1905017	biolink:NamedThing	positive regulation of isoleucine-tRNA ligase activity	Any process that activates or increases the frequency, rate or extent of isoleucine-tRNA ligase activity.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of isoleucyl-transfer RNA synthetase activity|activation of isoleucyl-tRNA synthetase activity|up regulation of L-isoleucine:tRNAIle ligase (AMP-forming)|activation of isoleucine-tRNA synthetase activity|up regulation of isoleucyl-transfer RNA synthetase activity|upregulation of L-isoleucine:tRNAIle ligase (AMP-forming)|activation of isoleucine-transfer RNA ligase activity|positive regulation of isoleucine-transfer RNA ligase activity|positive regulation of isoleucyl-tRNA synthetase activity|upregulation of isoleucyl-transfer ribonucleate synthetase activity|up-regulation of isoleucine-transfer RNA ligase activity|up regulation of isoleucyl-transfer ribonucleate synthetase activity|positive regulation of isoleucyl-transfer RNA synthetase activity|up-regulation of isoleucine-tRNA ligase activity|up regulation of isoleucine-transfer RNA ligase activity|positive regulation of isoleucine-tRNA synthetase activity|up-regulation of isoleucyl-tRNA synthetase activity|up regulation of isoleucine translase activity|upregulation of isoleucyl-transfer RNA synthetase activity|up-regulation of isoleucyl-transfer ribonucleate synthetase activity|up-regulation of L-isoleucine:tRNAIle ligase (AMP-forming)|up regulation of isoleucine-tRNA ligase activity|activation of isoleucyl-transfer ribonucleate synthetase activity|up-regulation of isoleucine-tRNA synthetase activity|positive regulation of isoleucine translase activity|up regulation of isoleucine-tRNA synthetase activity|positive regulation of isoleucyl-transfer ribonucleate synthetase activity|upregulation of isoleucyl-tRNA synthetase activity|activation of isoleucine-tRNA ligase activity|upregulation of isoleucine translase activity|upregulation of isoleucine-tRNA ligase activity|positive regulation of L-isoleucine:tRNAIle ligase (AMP-forming)|activation of isoleucyl-transfer RNA synthetase activity|upregulation of isoleucine-tRNA synthetase activity|activation of isoleucine translase activity|up-regulation of isoleucine translase activity|activation of L-isoleucine:tRNAIle ligase (AMP-forming)|up regulation of isoleucyl-tRNA synthetase activity|upregulation of isoleucine-transfer RNA ligase activity							sl	2016-03-03T19:01:06Z					biological_process											owl:Class	
GO:1905015	biolink:NamedThing	regulation of isoleucine-tRNA ligase activity	Any process that modulates the frequency, rate or extent of isoleucine-tRNA ligase activity.	tmpzr1t_l9r_go_relaxed.owl	regulation of isoleucine translase activity|regulation of L-isoleucine:tRNAIle ligase (AMP-forming)|regulation of isoleucine-transfer RNA ligase activity|regulation of isoleucyl-tRNA synthetase activity|regulation of isoleucyl-transfer RNA synthetase activity|regulation of isoleucine-tRNA synthetase activity|regulation of isoleucyl-transfer ribonucleate synthetase activity							sl	2016-03-03T19:00:48Z					biological_process											owl:Class	
GO:0019528	biolink:NamedThing	D-arabitol catabolic process to xylulose 5-phosphate	The chemical reactions and pathways resulting in the breakdown of D-arabitol to form xylulose 5-phosphate. D-arabitol is converted into D-xylulose, which is then phosphorylated to form D-xylulose-5-phosphate.	tmpzr1t_l9r_go_relaxed.owl	D-arabitol breakdown to xylulose 5-phosphate|D-arabitol degradation to xylulose 5-phosphate|D-arabitol utilization|D-arabitol degradation				MetaCyc:DARABITOLUTIL-PWY									biological_process											owl:Class	
GO:0051159	biolink:NamedThing	D-arabitol catabolic process	The chemical reactions and pathways resulting in the breakdown of D-arabitol, the pentitol derived from arabinose or lyxose by reduction of the aldehyde group. The D enantiomer is present in lichens and mushrooms.	tmpzr1t_l9r_go_relaxed.owl	D-arabitol catabolism|D-arabitol breakdown|D-arabitol degradation													biological_process											owl:Class	
GO:0019645	biolink:NamedThing	anaerobic electron transport chain	A process in which a series of electron carriers operate together to transfer electrons from donors such as NADH and FADH2 to any of several different terminal electron acceptors other than oxygen to generate a transmembrane electrochemical gradient.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0022904	biolink:NamedThing	respiratory electron transport chain	A process in which a series of electron carriers operate together to transfer electrons from donors such as NADH and FADH2 to any of several different terminal electron acceptors to generate a transmembrane electrochemical gradient.	tmpzr1t_l9r_go_relaxed.owl	dihydropteridine reduction|dihydrolipoylprotein reduction|dihydrobiopterin reduction|other pathways of electron transport|protein-disulfide reduction|electron transfer|dihydrolipoamide reduction|oxidized glutathione reduction|6-phosphofructokinase reduction				Wikipedia:Electron_transfer									biological_process											owl:Class	
GO:0033303	biolink:NamedThing	quercetin O-glucoside biosynthetic process	The chemical reactions and pathways leading to the formation of O-glucosylated derivatives of quercetin.	tmpzr1t_l9r_go_relaxed.owl	quercetin O-glucoside formation|quercetin O-glucoside biosynthesis|quercetin O-glucoside anabolism|quercetin O-glucoside synthesit				MetaCyc:PWY-5321									biological_process											owl:Class	
GO:0033302	biolink:NamedThing	quercetin O-glucoside metabolic process	The chemical reactions and pathways involving O-glucosylated derivatives of quercetin.	tmpzr1t_l9r_go_relaxed.owl	quercetin O-glucoside metabolism													biological_process											owl:Class	
GO:0002840	biolink:NamedThing	regulation of T cell mediated immune response to tumor cell	Any process that modulates the frequency, rate, or extent of a T cell mediated immune response to tumor cell.	tmpzr1t_l9r_go_relaxed.owl	regulation of T-cell mediated immune response to tumor cell|regulation of T cell mediated immune response to tumour cell|regulation of T-lymphocyte mediated immune response to tumor cell|regulation of T lymphocyte mediated immune response to tumor cell													biological_process											owl:Class	
GO:0002837	biolink:NamedThing	regulation of immune response to tumor cell	Any process that modulates the frequency, rate, or extent of an immune response to tumor cell.	tmpzr1t_l9r_go_relaxed.owl	regulation of immune response to tumour cell													biological_process											owl:Class	
GO:0006004	biolink:NamedThing	fucose metabolic process	The chemical reactions and pathways involving fucose, or 6-deoxygalactose, which has two enantiomers, D-fucose and L-fucose.	tmpzr1t_l9r_go_relaxed.owl	fucose metabolism													biological_process											owl:Class	
GO:0000164	biolink:NamedThing	protein phosphatase type 1 complex	A protein complex that possesses magnesium-dependent protein serine/threonine phosphatase (AMD phosphatase) activity, and consists of a catalytic subunit and one or more regulatory subunits that dictates the phosphatase's substrate specificity, function, and activity.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0008287	biolink:NamedThing	protein serine/threonine phosphatase complex	A complex, normally consisting of a catalytic and a regulatory subunit, which catalyzes the removal of a phosphate group from a serine or threonine residue of a protein.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0034702	biolink:NamedThing	ion channel complex	A protein complex that spans a membrane and forms a water-filled channel across the phospholipid bilayer allowing selective ion transport down its electrochemical gradient.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0031030	biolink:NamedThing	negative regulation of septation initiation signaling	Any process that stops, prevents, or reduces the frequency, rate or extent of septation initiation signaling.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of septation initiation signaling cascade|downregulation of septation initiation signaling|inhibition of septation initiation signaling|down regulation of septation initiation signaling|down-regulation of septation initiation signaling|negative regulation of septation initiation signalling|negative regulation of septation initiation network													biological_process											owl:Class	
GO:0031029	biolink:NamedThing	regulation of septation initiation signaling	Any process that modulates the frequency, rate or extent of septation initiation signaling.	tmpzr1t_l9r_go_relaxed.owl	regulation of septation initiation network|regulation of septation initiation signalling|regulation of septation initiation signaling cascade													biological_process											owl:Class	
GO:0061902	biolink:NamedThing	negative regulation of 1-phosphatidylinositol-3-kinase activity	Any process that stops, prevents or reduces the frequency, rate or extent of 1-phosphatidylinositol-3-kinase activity.	tmpzr1t_l9r_go_relaxed.owl								dph	2017-06-22T19:51:34Z					biological_process											owl:Class	
GO:0050603	biolink:NamedThing	thiophene-2-carbonyl-CoA monooxygenase activity	Catalysis of the reaction: AH(2) + O(2) + thiophene-2-carbonyl-CoA = 5-hydroxythiophene-2-carbonyl-CoA + A + H(2)O + H(+).	tmpzr1t_l9r_go_relaxed.owl	thiophene-2-carbonyl-CoA, hydrogen-donor:oxygen oxidoreductase activity|thiophene-2-carboxyl-CoA monooxygenase activity|thiophene-2-carboxyl-CoA hydroxylase activity|thiophene-2-carboxyl-CoA dehydrogenase activity				UM-BBD_reactionID:r1235|RHEA:18929|MetaCyc:1.14.99.35-RXN|KEGG_REACTION:R05742|EC:1.14.99.35									molecular_function											owl:Class	
GO:1900622	biolink:NamedThing	positive regulation of transcription from RNA polymerase II promoter by calcium-mediated signaling	Calcium-mediated signaling that results in positive regulation of transcription from an RNA polymerase II promoter.	tmpzr1t_l9r_go_relaxed.owl	calcineurin-mediated activation of transcription|upregulation of transcription from RNA polymerase II promoter by calcium-mediated signaling|up regulation of global transcription from RNA polymerase II promoter by calcium-mediated signaling|calcineurin-dependent transcription activation|positive regulation of transcription from Pol II promoter by calcium-mediated signaling|stimulation of transcription from RNA polymerase II promoter by calcium-mediated signaling|upregulation of global transcription from RNA polymerase II promoter by calcium-mediated signaling|calcineurin-dependent transcriptional induction|up-regulation of transcription from RNA polymerase II promoter by calcium-mediated signaling|positive regulation of global transcription from Pol II promoter by calcium-mediated signaling|up regulation of transcription from RNA polymerase II promoter by calcium-mediated signaling|up-regulation of global transcription from RNA polymerase II promoter by calcium-mediated signaling|stimulation of global transcription from RNA polymerase II promoter by calcium-mediated signaling|activation of transcription from RNA polymerase II promoter by calcium-mediated signaling|activation of global transcription from RNA polymerase II promoter by calcium-mediated signaling|positive regulation of transcription from RNA polymerase II promoter, global by calcium-mediated signaling|positive regulation of gene-specific transcription from RNA polymerase II promoter by calcium-mediated signaling							bf	2012-05-18T01:01:04Z					biological_process											owl:Class	
GO:0019722	biolink:NamedThing	calcium-mediated signaling	Any intracellular signal transduction in which the signal is passed on within the cell via calcium ions.	tmpzr1t_l9r_go_relaxed.owl	calcium ion signaling|calcium signaling|calcium signalling|calcium-mediated signalling				Wikipedia:Calcium_signaling									biological_process											owl:Class	
GO:2000051	biolink:NamedThing	negative regulation of non-canonical Wnt signaling pathway	Any process that stops, prevents, or reduces the frequency, rate or extent of non-canonical Wnt signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of non-canonical Wnt receptor signalling pathway|negative regulation of non-canonical Wnt-activated signaling pathway|negative regulation of beta-catenin-independent Wnt receptor signaling pathway|negative regulation of non-canonical Wnt receptor signaling pathway							jl	2010-08-20T01:04:20Z					biological_process											owl:Class	
GO:0030178	biolink:NamedThing	negative regulation of Wnt signaling pathway	Any process that stops, prevents, or reduces the frequency, rate or extent of the Wnt signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	inhibition of Wnt receptor signaling pathway|negative regulation of frizzled signalling pathway|negative regulation of Wnt receptor signalling pathway|down regulation of frizzled signaling pathway|down regulation of Wnt receptor signaling pathway|negative regulation of Wnt-activated signaling pathway|negative regulation of frizzled signaling pathway|downregulation of frizzled signaling pathway|down-regulation of Wnt receptor signaling pathway|down-regulation of frizzled signaling pathway|inhibition of frizzled signaling pathway|downregulation of Wnt receptor signaling pathway|negative regulation of Wnt receptor signaling pathway											GO:0045810		biological_process											owl:Class	
GO:1900292	biolink:NamedThing	negative regulation of galactotriose transport	Any process that stops, prevents or reduces the frequency, rate or extent of galactotriose transport.	tmpzr1t_l9r_go_relaxed.owl	inhibition of galactotriose transport|downregulation of galactotriose transport|down regulation of galactotriose transport|down-regulation of galactotriose transport							tt	2012-04-05T07:26:08Z					biological_process											owl:Class	
GO:0097700	biolink:NamedThing	vascular endothelial cell response to laminar fluid shear stress	Any response to laminar fluid shear stress in a vascular endothelial cell.	tmpzr1t_l9r_go_relaxed.owl	blood vessel endothelial cell response to laminar fluid shear stress							pr	2016-01-27T12:42:01Z					biological_process											owl:Class	
GO:0097699	biolink:NamedThing	vascular endothelial cell response to fluid shear stress	Any response to fluid shear stress in a vascular endothelial cell.	tmpzr1t_l9r_go_relaxed.owl	blood vessel endothelial cell response to fluid shear stress							pr	2016-01-27T12:37:32Z					biological_process											owl:Class	
GO:0044393	biolink:NamedThing	microspike	A dynamic, actin-rich projection extending from the surface of a migrating animal cell.	tmpzr1t_l9r_go_relaxed.owl						Although in some literature 'microspike' and 'filopodium' are used synonymously, in GO microspike refers to a cell projection that is distinct from a filopodium. See also 'filopodium ; GO:0030175'.		bf	2011-12-06T01:31:16Z					cellular_component											owl:Class	
GO:0015821	biolink:NamedThing	methionine transport	The directed movement of methionine, 2-amino-4-(methylthio)butanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	L-methionine transport													biological_process											owl:Class	
GO:0043242	biolink:NamedThing	negative regulation of protein-containing complex disassembly	Any process that stops, prevents, or reduces the frequency, rate or extent of protein complex disassembly, the disaggregation of a protein complex into its constituent components.	tmpzr1t_l9r_go_relaxed.owl	down regulation of protein complex disassembly|down-regulation of protein complex disassembly|downregulation of protein complex disassembly|inhibition of protein complex disassembly|negative regulation of protein complex disassembly													biological_process											owl:Class	
GO:0043244	biolink:NamedThing	regulation of protein-containing complex disassembly	Any process that modulates the frequency, rate or extent of protein complex disassembly, the disaggregation of a protein complex into its constituent components.	tmpzr1t_l9r_go_relaxed.owl	regulation of protein complex disassembly													biological_process											owl:Class	
GO:0016320	biolink:NamedThing	endoplasmic reticulum membrane fusion	The joining of 2 or more lipid bilayer membranes that surround the endoplasmic reticulum.	tmpzr1t_l9r_go_relaxed.owl	ER membrane fusion													biological_process											owl:Class	
GO:0090174	biolink:NamedThing	organelle membrane fusion	The joining of two lipid bilayers to form a single organelle membrane.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-12-11T11:44:58Z					biological_process											owl:Class	
GO:0010059	biolink:NamedThing	positive regulation of atrichoblast fate specification	Any process that induces or promotes atrichoblast fate specification.	tmpzr1t_l9r_go_relaxed.owl	stimulation of atrichoblast fate|up-regulation of atrichoblast fate|activation of atrichoblast fate|up regulation of atrichoblast fate|upregulation of atrichoblast fate													biological_process											owl:Class	
GO:0061764	biolink:NamedThing	late endosome to lysosome transport via multivesicular body sorting pathway	The directed movement of substances from late endosomes to lysosomes by a pathway in which molecules are sorted into multivesicular bodies, which then fuse with the lysosome.	tmpzr1t_l9r_go_relaxed.owl								dph	2016-04-19T09:29:57Z					biological_process											owl:Class	
GO:0032510	biolink:NamedThing	endosome to lysosome transport via multivesicular body sorting pathway	The directed movement of substances from endosomes to lysosomes by a pathway in which molecules are sorted into multivesicular bodies, which then fuse with the lysosome.	tmpzr1t_l9r_go_relaxed.owl	endosome to lysosome transport via MVB sorting pathway													biological_process											owl:Class	
GO:0048691	biolink:NamedThing	positive regulation of axon extension involved in regeneration	Any process that activates, maintains or increases the rate of axon extension involved in regeneration.	tmpzr1t_l9r_go_relaxed.owl	activation of axon extension involved in regeneration|up-regulation of axon extension involved in regeneration|stimulation of axon extension involved in regeneration|upregulation of axon extension involved in regeneration|up regulation of axon extension involved in regeneration													biological_process											owl:Class	
GO:0050968	biolink:NamedThing	detection of chemical stimulus involved in sensory perception of pain	The series of events involved in the perception of pain in which a chemical stimulus is received and converted into a molecular signal.	tmpzr1t_l9r_go_relaxed.owl	perception of pain, sensory detection of chemical stimulus|sensory detection of chemical stimulus during perception of pain|perception of pain, detection of chemical stimulus|perception of pain, sensory transduction of chemical stimulus|sensory transduction of chemical stimulus during perception of pain|chemical nociception													biological_process											owl:Class	
GO:0021839	biolink:NamedThing	interneuron-substratum interaction involved in interneuron migration from the subpallium to the cortex	The process in which migrating interneurons interact with an external substratum as a component of migration from the subpallium to the cortex.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0036489	biolink:NamedThing	neuromelanin biosynthetic process	The chemical reactions and pathways resulting in the formation of neuromelanin. Neuromelanin is a polymer of 5,6-dihydroxyindole monomers.	tmpzr1t_l9r_go_relaxed.owl	neuromelanin formation|neuromelanin synthesis|neuromelanin anabolism|neuromelanin biosynthesis							bf	2014-11-06T13:21:46Z					biological_process											owl:Class	
GO:1901535	biolink:NamedThing	regulation of DNA demethylation	Any process that modulates the frequency, rate or extent of DNA demethylation.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-10-24T13:52:50Z					biological_process											owl:Class	
GO:0051052	biolink:NamedThing	regulation of DNA metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving DNA.	tmpzr1t_l9r_go_relaxed.owl	regulation of DNA metabolism													biological_process											owl:Class	
GO:0004838	biolink:NamedThing	L-tyrosine:2-oxoglutarate aminotransferase activity	Catalysis of the reaction: L-tyrosine + 2-oxoglutarate = 4-hydroxyphenylpyruvate + L-glutamate.	tmpzr1t_l9r_go_relaxed.owl	L-phenylalanine 2-oxoglutarate aminotransferase activity|glutamic-hydroxyphenylpyruvic transaminase activity|tyrosine-alpha-ketoglutarate transaminase activity|tyrosine transaminase activity|L-tyrosine aminotransferase activity|tyrosine-alpha-ketoglutarate aminotransferase activity|phenylpyruvate transaminase activity|glutamic phenylpyruvic aminotransferase activity|phenylalanine transaminase activity|phenylalanine-alpha-ketoglutarate transaminase activity|TyrAT activity|phenylpyruvic acid transaminase activity|tyrosine aminotransferase activity|phenylalanine aminotransferase activity|tyrosine-2-ketoglutarate aminotransferase activity				RHEA:15093|EC:2.6.1.5|Reactome:R-HSA-71155|MetaCyc:TYROSINE-AMINOTRANSFERASE-RXN|Reactome:R-HSA-517444									molecular_function											owl:Class	
GO:0070547	biolink:NamedThing	L-tyrosine aminotransferase activity	Catalysis of the transfer of an amino group from L-tyrosine to an acceptor, usually a 2-oxo acid.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0061883	biolink:NamedThing	clathrin-dependent endocytosis involved in vitellogenesis	A clathrin-mediated endocytosis process whereby yolk proteins are internalized and trafficked through the endocytic pathway for yolk deposition.	tmpzr1t_l9r_go_relaxed.owl	clathrin-dependent endocytosis involved in yolk formation							dph	2017-05-30T14:41:21Z					biological_process											owl:Class	
GO:1900941	biolink:NamedThing	regulation of (Z)-nonadeca-1,14-diene biosynthetic process	Any process that modulates the frequency, rate or extent of (Z)-nonadeca-1,14-diene biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of (Z)-nonadeca-1,14-diene formation|regulation of (Z)-nonadeca-1,14-diene biosynthesis|regulation of (Z)-nonadeca-1,14-diene anabolism|regulation of (Z)-nonadeca-1,14-diene synthesis							tt	2012-06-14T03:17:32Z					biological_process											owl:Class	
GO:0060679	biolink:NamedThing	trifid subdivision of terminal units involved in ureteric bud branching	The process in which a ureteric bud splits into three units at its end.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-06-02T02:37:42Z					biological_process											owl:Class	
GO:0032565	biolink:NamedThing	dGMP binding	Binding to dGMP, deoxyguanosine monophosphate.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1903490	biolink:NamedThing	positive regulation of mitotic cytokinesis	Any process that activates or increases the frequency, rate or extent of mitotic cytokinesis.	tmpzr1t_l9r_go_relaxed.owl	upregulation of cytokinesis after mitosis|up regulation of cytokinesis after mitosis|up-regulation of cytokinesis after mitosis|activation of cytokinesis after mitosis|positive regulation of cytokinesis after mitosis|activation of mitotic cytokinesis|up regulation of mitotic cytokinesis|up-regulation of mitotic cytokinesis|upregulation of mitotic cytokinesis							al	2014-09-25T09:00:35Z					biological_process											owl:Class	
GO:0042342	biolink:NamedThing	cyanogenic glycoside catabolic process	The chemical reactions and pathways resulting in the breakdown of cyanogenic glycosides, any glycoside containing a cyano group that is released as hydrocyanic acid on acid hydrolysis; such compounds occur in the kernels of various fruits.	tmpzr1t_l9r_go_relaxed.owl	cyanogenic glycoside catabolism|cyanogenic glycoside degradation|cyanogenic glycoside breakdown													biological_process											owl:Class	
GO:0050899	biolink:NamedThing	nitrile catabolic process	The chemical reactions and pathways resulting in the breakdown of a nitrile, an organic compound containing trivalent nitrogen attached to one carbon atom.	tmpzr1t_l9r_go_relaxed.owl	nitrile catabolism|nitrile degradation|nitrile breakdown													biological_process											owl:Class	
GO:1901542	biolink:NamedThing	regulation of ent-pimara-8(14),15-diene biosynthetic process	Any process that modulates the frequency, rate or extent of ent-pimara-8(14),15-diene biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of ent-pimara-8(14),15-diene synthesis|regulation of ent-pimara-8(14),15-diene biosynthesis|regulation of ent-pimara-8(14),15-diene anabolism|regulation of ent-pimara-8(14),15-diene formation							di	2012-10-26T11:37:54Z					biological_process											owl:Class	
GO:0070618	biolink:NamedThing	Grb2-Sos complex	A protein complex that contains Grb2 and the guanine nucleotide exchange factor Sos (or an ortholog thereof, such as mSos1), and is involved in linking EGFR activation to the p21-Ras pathway.	tmpzr1t_l9r_go_relaxed.owl	Grb2-mSos1 complex							mah	2009-04-29T04:19:02Z					cellular_component											owl:Class	
GO:0071964	biolink:NamedThing	establishment of cell polarity regulating cell shape	Any cellular process that results in the specification or formation of a polarized intracellular organization or cell growth pattern that regulates the shape of a cell.	tmpzr1t_l9r_go_relaxed.owl								mah	2011-06-22T03:10:08Z					biological_process											owl:Class	
GO:0030010	biolink:NamedThing	establishment of cell polarity	The specification and formation of anisotropic intracellular organization or cell growth patterns.	tmpzr1t_l9r_go_relaxed.owl	cell polarization|bud site selection/establishment of cell polarity											GO:0000283|GO:0030468		biological_process											owl:Class	
GO:0097277	biolink:NamedThing	cellular urea homeostasis	Any biological process involved in the maintenance of an internal steady state of urea at the level of the cell.	tmpzr1t_l9r_go_relaxed.owl								pr	2012-03-22T02:57:08Z					biological_process											owl:Class	
GO:0097274	biolink:NamedThing	urea homeostasis	Any biological process involved in the maintenance of an internal steady state of urea.	tmpzr1t_l9r_go_relaxed.owl								pr	2012-03-22T02:53:39Z					biological_process											owl:Class	
GO:0001848	biolink:NamedThing	complement binding	Binding to a component or product of the complement cascade.	tmpzr1t_l9r_go_relaxed.owl						Note that the complement cascade includes all of the components involved in the classical complement pathway, the alternative complement pathway, and the lectin complement pathway, as well as the common components of all three pathways.								molecular_function											owl:Class	
GO:1901494	biolink:NamedThing	regulation of cysteine metabolic process	Any process that modulates the frequency, rate or extent of cysteine metabolic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of cysteine metabolism							vw	2012-10-16T14:28:42Z					biological_process											owl:Class	
GO:0006521	biolink:NamedThing	regulation of cellular amino acid metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving amino acids.	tmpzr1t_l9r_go_relaxed.owl	regulation of amino acid metabolism													biological_process											owl:Class	
GO:0008069	biolink:NamedThing	dorsal/ventral axis specification, ovarian follicular epithelium	Polarization of the ovarian follicle cells along the dorsal/ventral axis. An example of this process is found in Drosophila melanogaster.	tmpzr1t_l9r_go_relaxed.owl	dorsal-ventral axis specification, ovarian follicular epithelium|dorsal/ventral axis determination, ovarian follicular epithelium|dorsoventral axis specification, ovarian follicular epithelium|dorsal/ventral axis determination, follicular epithelium													biological_process											owl:Class	
GO:0016334	biolink:NamedThing	establishment or maintenance of polarity of follicular epithelium	Any cellular process that results in the specification, formation or maintenance of a polarized follicular epithelial sheet.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1905240	biolink:NamedThing	negative regulation of canonical Wnt signaling pathway involved in osteoblast differentiation	Any process that stops, prevents or reduces the frequency, rate or extent of canonical Wnt signaling pathway involved in osteoblast differentiation.	tmpzr1t_l9r_go_relaxed.owl	downregulation of canonical Wnt signaling pathway involved in osteoblast differentiation|down-regulation of canonical Wnt signaling pathway involved in osteoblast differentiation|negative regulation of canonical Wnt receptor signalling pathway involved in osteoblast differentiation|down regulation of canonical Wnt receptor signalling pathway involved in osteoblast differentiation|down-regulation of canonical Wnt-activated signaling pathway involved in osteoblast differentiation|negative regulation of canonical Wnt receptor signaling pathway involved in osteoblast differentiation|downregulation of canonical Wnt receptor signalling pathway involved in osteoblast differentiation|down-regulation of canonical Wnt receptor signaling pathway involved in osteoblast differentiation|inhibition of canonical Wnt signaling pathway involved in osteoblast differentiation|down regulation of canonical Wnt signaling pathway involved in osteoblast differentiation|down regulation of canonical Wnt receptor signaling pathway involved in osteoblast differentiation|negative regulation of canonical Wnt-activated signaling pathway involved in osteoblast differentiation|downregulation of canonical Wnt receptor signaling pathway involved in osteoblast differentiation|downregulation of canonical Wnt-activated signaling pathway involved in osteoblast differentiation|inhibition of canonical Wnt receptor signaling pathway involved in osteoblast differentiation|down-regulation of canonical Wnt receptor signalling pathway involved in osteoblast differentiation|inhibition of canonical Wnt-activated signaling pathway involved in osteoblast differentiation|inhibition of canonical Wnt receptor signalling pathway involved in osteoblast differentiation|down regulation of canonical Wnt-activated signaling pathway involved in osteoblast differentiation							rph	2016-06-08T10:26:41Z					biological_process											owl:Class	
GO:2000990	biolink:NamedThing	positive regulation of hemicellulose catabolic process	Any process that activates or increases the frequency, rate or extent of hemicellulose catabolic process.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of hemicellulose catabolism							tt	2011-08-08T03:08:23Z					biological_process											owl:Class	
GO:0010676	biolink:NamedThing	positive regulation of cellular carbohydrate metabolic process	Any process that increases the rate, extent or frequency of the chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y, as carried out by individual cells.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0052053	biolink:NamedThing	negative regulation by symbiont of host catalytic activity	Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of host enzyme activity. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	negative regulation by symbiont of host enzyme activity|inhibition of host enzyme activity|downregulation by symbiont of host enzyme activity|down-regulation by symbiont of host enzyme activity|down regulation by symbiont of host enzyme activity|inhibition by symbiont of host enzyme activity|negative regulation by symbiont of host molecular function											GO:0052056		biological_process											owl:Class	
GO:0008476	biolink:NamedThing	protein-tyrosine sulfotransferase activity	Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + protein tyrosine = adenosine 3',5'-bisphosphate + protein tyrosine-O-sulfate.	tmpzr1t_l9r_go_relaxed.owl	protein-tyrosine sulphotransferase activity|3'-phosphoadenylyl-sulfate:protein-tyrosine O-sulfotransferase activity|tyrosylprotein sulfotransferase activity				MetaCyc:PROTEIN-TYROSINE-SULFOTRANSFERASE-RXN|RHEA:16801|Reactome:R-HSA-9668148|EC:2.8.2.20|Reactome:R-HSA-8954262|Reactome:R-HSA-9668023									molecular_function											owl:Class	
GO:0048674	biolink:NamedThing	collateral sprouting of injured axon	The process resulting in reformation of a growth cone by the tip of an injured axon, or in collateral sprouting of the axon. Collateral sprouting is the process in which outgrowths develop from the shafts of existing axons.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0048682	biolink:NamedThing	sprouting of injured axon	The process involved in sprouting of an injured axon.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0043442	biolink:NamedThing	acetoacetic acid catabolic process	The chemical reactions and pathways resulting in the breakdown of acetoacetic acid, a beta-keto acid of the keto acid group, empirical formula is C4H6O3 or CH3COCH2COOH.	tmpzr1t_l9r_go_relaxed.owl	acetoacetic acid catabolism|acetoacetic acid breakdown|acetoacetic acid degradation													biological_process											owl:Class	
GO:0043438	biolink:NamedThing	acetoacetic acid metabolic process	The chemical reactions and pathways involving acetoacetic acid, 3-oxobutanoic acid; the empirical formula is C4H6O3 or CH3COCH2COOH.	tmpzr1t_l9r_go_relaxed.owl	3-oxobutanoic acid metabolism|beta ketobutyric acid metabolic process|beta-ketobutyric acid metabolism|diacetic acid metabolic process|acetoacetate metabolism|acetoacetic acid metabolism|3-oxobutanoic acid metabolic process|acetoacetate metabolic process|beta-ketobutyric acid metabolic process|3-oxobutanoate metabolic process|diacetic acid metabolism|3-oxobutanoate metabolism|beta ketobutyric acid metabolism													biological_process											owl:Class	
GO:0004148	biolink:NamedThing	dihydrolipoyl dehydrogenase activity	Catalysis of the reaction: protein N6-(dihydrolipoyl)lysine + NAD+ = protein N6-(lipoyl)lysine + NADH + H+.	tmpzr1t_l9r_go_relaxed.owl	lipoic acid dehydrogenase activity|dihydrolipoamide:NAD+ oxidoreductase|dihydrolipoic dehydrogenase activity|diaphorase activity|dehydrolipoate dehydrogenase activity|lipoamide reductase activity|L-protein activity|lipoamide dehydrogenase (NADH) activity|lipoamide reductase (NADH) activity|glycine-cleavage system L-protein activity|protein-6-N-(dihydrolipoyl)lysine:NAD+ oxidoreductase|lipoate dehydrogenase activity|E3 component of alpha-ketoacid dehydrogenase complexes activity|lipoamide oxidoreductase (NADH) activity|protein-N6-(dihydrolipoyl)lysine:NAD+ oxidoreductase|dihydrolipoamide dehydrogenase activity|dihydrolipoamide reduction|LDP-Val activity|LDP-Glc activity|lipoyl dehydrogenase activity|dihydrolipoylprotein reduction|dihydrothioctic dehydrogenase activity				RHEA:15045|MetaCyc:DIHYDLIPOXN-RXN|EC:1.8.1.4|Reactome:R-HSA-5694018|Reactome:R-HSA-1222412									molecular_function											owl:Class	
GO:0072550	biolink:NamedThing	triferuloylspermidine meta-hydroxylase activity	Catalysis of the reaction: triferuloyl spermidine + NADPH + O2 = diferuloyl mono-(hydroxyferuloyl) spermidine + NADP+ + H2O.	tmpzr1t_l9r_go_relaxed.owl	triferuloyl spermidine meta-hydroxylase activity				MetaCyc:RXN-11262			mah	2011-01-25T02:58:56Z					molecular_function											owl:Class	
GO:1903689	biolink:NamedThing	regulation of wound healing, spreading of epidermal cells	Any process that modulates the frequency, rate or extent of wound healing, spreading of epidermal cells.	tmpzr1t_l9r_go_relaxed.owl								als	2014-12-01T15:54:18Z					biological_process											owl:Class	
GO:1900944	biolink:NamedThing	regulation of isoprene metabolic process	Any process that modulates the frequency, rate or extent of isoprene metabolic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of 2-methyl-1,3-butadiene metabolic process|regulation of isoprene metabolism|regulation of hemiterpene metabolic process|regulation of hemiterpene metabolism|regulation of 2-methyl-1,3-butadiene metabolism							tt	2012-06-14T03:19:13Z					biological_process											owl:Class	
GO:0019747	biolink:NamedThing	regulation of isoprenoid metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving isoprenoids.	tmpzr1t_l9r_go_relaxed.owl	regulation of isoprenoid metabolism													biological_process											owl:Class	
GO:0032960	biolink:NamedThing	regulation of inositol trisphosphate biosynthetic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of inositol trisphosphate.	tmpzr1t_l9r_go_relaxed.owl	regulation of inositol trisphosphate anabolism|regulation of IP3 biosynthetic process|regulation of IP3 biosynthesis|regulation of inositol trisphosphate synthesis|regulation of inositol trisphosphate biosynthesis|regulation of myo-inositol trisphosphate biosynthetic process|regulation of myo-inositol trisphosphate biosynthesis|regulation of inositol trisphosphate formation													biological_process											owl:Class	
GO:2000735	biolink:NamedThing	positive regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation	Any process that activates or increases the frequency, rate or extent of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of glial cell-derived neurotrophic factor receptor signaling pathway of ureteric bud formation|positive regulation of GDNF receptor signaling pathway of ureteric bud formation|positive regulation of glial cell line-derived neurotrophic factor receptor signalling pathway of ureteric bud formation|positive regulation of glial cell-derived neurotrophic factor receptor signalling pathway of ureteric bud formation|positive regulation of glial cell derived neurotrophic factor receptor signaling pathway of ureteric bud formation							yaf	2011-06-13T11:14:46Z					biological_process											owl:Class	
GO:2000996	biolink:NamedThing	positive regulation of mannan catabolic process	Any process that activates or increases the frequency, rate or extent of mannan catabolic process.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of mannan degradation|positive regulation of mannan breakdown|positive regulation of mannan catabolism							tt	2011-08-08T03:19:18Z					biological_process											owl:Class	
GO:0042288	biolink:NamedThing	MHC class I protein binding	Binding to a major histocompatibility complex class I molecule; a set of molecules displayed on cell surfaces that are responsible for lymphocyte recognition and antigen presentation.	tmpzr1t_l9r_go_relaxed.owl	major histocompatibility complex class I ligand|major histocompatibility complex class I binding|alpha-beta T cell receptor activity|T cell receptor activity|gamma-delta T cell receptor activity					Note that this term does not include binding to the antigen peptide bound to the MHC protein. Consider also annotating to the molecular function term 'peptide antigen binding ; GO:0042605' or one of its children.								molecular_function											owl:Class	
GO:0042287	biolink:NamedThing	MHC protein binding	Binding to a major histocompatibility complex molecule; a set of molecules displayed on cell surfaces that are responsible for lymphocyte recognition and antigen presentation.	tmpzr1t_l9r_go_relaxed.owl	major histocompatibility complex binding|major histocompatibility complex ligand					Note that this term does not include binding to the antigen peptide bound to the MHC protein, for this also annotate to 'peptide antigen binding ; GO:0042605' or one of its children.								molecular_function											owl:Class	
GO:0051004	biolink:NamedThing	regulation of lipoprotein lipase activity	Any process that modulates the activity of the enzyme lipoprotein lipase.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0060191	biolink:NamedThing	regulation of lipase activity	Any process that modulates the frequency, rate or extent of lipase activity, the hydrolysis of a lipid or phospholipid.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:2000538	biolink:NamedThing	positive regulation of B cell chemotaxis	Any process that activates or increases the frequency, rate or extent of B cell chemotaxis.	tmpzr1t_l9r_go_relaxed.owl								ebc	2011-03-29T09:49:33Z					biological_process											owl:Class	
GO:2000537	biolink:NamedThing	regulation of B cell chemotaxis	Any process that modulates the frequency, rate or extent of B cell chemotaxis.	tmpzr1t_l9r_go_relaxed.owl								ebc	2011-03-29T09:49:25Z					biological_process											owl:Class	
GO:0043446	biolink:NamedThing	cellular alkane metabolic process	The chemical reactions and pathways involving an alkane, any acyclic branched or unbranched hydrocarbon having the general formula CnH2n+2, as carried out by individual cells.	tmpzr1t_l9r_go_relaxed.owl	alkane metabolism													biological_process											owl:Class	
GO:0018792	biolink:NamedThing	bis(4-chlorophenyl)acetate decarboxylase activity	Catalysis of the reaction: bis(4-chlorophenyl)acetate + H+ = CO2 + bis(4-chlorophenyl)methane. Bis(4-chlorophenyl)acetate is also known as DDA; bis(4-chlorophenyl)methane is also known as DDM.	tmpzr1t_l9r_go_relaxed.owl	DDA decarboxylase activity				UM-BBD_reactionID:r0520									molecular_function											owl:Class	
GO:0004481	biolink:NamedThing	methylene-fatty-acyl-phospholipid synthase activity	Catalysis of the reaction: S-adenosyl-L-methionine + phospholipid olefinic fatty acid = S-adenosyl-L-homocysteine + phospholipid methylene fatty acid.	tmpzr1t_l9r_go_relaxed.owl	S-adenosyl-L-methionine:unsaturated-phospholipid methyltransferase (methenylating)|cyclopropane synthetase activity|unsaturated-phospholipid methyltransferase activity				EC:2.1.1.16|RHEA:17549|MetaCyc:2.1.1.16-RXN									molecular_function											owl:Class	
GO:0045773	biolink:NamedThing	positive regulation of axon extension	Any process that activates or increases the frequency, rate or extent of axon extension.	tmpzr1t_l9r_go_relaxed.owl	activation of axon extension|up-regulation of axon extension|stimulation of axon extension|up regulation of axon extension|upregulation of axon extension													biological_process											owl:Class	
GO:0042177	biolink:NamedThing	negative regulation of protein catabolic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of protein breakdown|negative regulation of protein catabolism|down regulation of protein catabolic process|negative regulation of protein degradation|downregulation of protein catabolic process|inhibition of protein catabolic process|down-regulation of protein catabolic process													biological_process											owl:Class	
GO:0097334	biolink:NamedThing	response to perphenazine	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a perphenazine stimulus. Perphenazine is a phenothiazine derivative having a chloro substituent at the 2-position and a 3-[4-(2-hydroxyethyl)piperazin-1-yl]propyl group at the N-10 position.	tmpzr1t_l9r_go_relaxed.owl								pr	2012-06-12T11:01:14Z					biological_process											owl:Class	
GO:0002255	biolink:NamedThing	tissue kallikrein-kinin cascade	A series of reactions that takes place outside the cell initiated by the action of tissue (glandular) kallikreins on low molecular weight kininogen in response to tissue damage. Tissue kallikreins are present in glandular tissues and their fluids, such as the salivary glands, sweat glands, pancreas, and kidney. The ultimate products of the tissue kallikrein-kinin cascade include kallidin and bradykinin, agents known to induce smooth muscle contraction, vasoconstriction, and increased vascular permeability.	tmpzr1t_l9r_go_relaxed.owl	glandular kallikrein-kinin cascade													biological_process											owl:Class	
GO:0002254	biolink:NamedThing	kinin cascade	A series of reactions that takes place outside the cell that occur as a result of by-products of tissue damage, including collagen, cartilage, and basement membrane. The ultimate product of the kinin cascade include kallidin and bradykinin, agents known to induce smooth muscle contraction, vasoconstriction, and increased vascular permeability.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0072752	biolink:NamedThing	cellular response to rapamycin	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a rapamycin stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2012-09-14T11:13:34Z					biological_process											owl:Class	
GO:1900290	biolink:NamedThing	positive regulation of coenzyme F420-dependent bicyclic nitroimidazole catabolic process	Any process that activates or increases the frequency, rate or extent of coenzyme F420-dependent bicyclic nitroimidazole catabolic process.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of coenzyme F420-dependent nitroimidazole breakdown|positive regulation of coenzyme F420-dependent nitroreductase activity|upregulation of coenzyme F420-dependent nitroimidazole reduction|positive regulation of coenzyme F420-dependent nitroimidazole catabolism|upregulation of coenzyme F420-dependent nitroimidazole breakdown|up-regulation of coenzyme F420-dependent nitroreductase activity|up regulation of coenzyme F420-dependent nitroimidazole breakdown|activation of coenzyme F420-dependent nitroimidazole breakdown|up-regulation of coenzyme F420-dependent bicyclic nitroimidazole catabolic process|up regulation of coenzyme F420-dependent nitroreductase activity|up-regulation of coenzyme F420-dependent nitroimidazole breakdown|positive regulation of coenzyme F420-dependent nitroimidazole reduction|activation of coenzyme F420-dependent nitroimidazole reduction|activation of coenzyme F420-dependent nitroreductase activity|upregulation of coenzyme F420-dependent bicyclic nitroimidazole catabolic process|up-regulation of coenzyme F420-dependent nitroimidazole catabolism|activation of coenzyme F420-dependent bicyclic nitroimidazole catabolic process|upregulation of coenzyme F420-dependent nitroreductase activity|up regulation of coenzyme F420-dependent bicyclic nitroimidazole catabolic process|activation of coenzyme F420-dependent nitroimidazole catabolism|upregulation of coenzyme F420-dependent nitroimidazole catabolism|up-regulation of coenzyme F420-dependent nitroimidazole reduction|up regulation of coenzyme F420-dependent nitroimidazole reduction|up regulation of coenzyme F420-dependent nitroimidazole catabolism							tt	2012-04-05T06:02:59Z					biological_process											owl:Class	
GO:1902638	biolink:NamedThing	neural crest cell differentiation involved in parathyroid gland development	Any neural crest cell differentiation that is involved in parathyroid gland development.	tmpzr1t_l9r_go_relaxed.owl								pr	2014-01-21T10:03:29Z					biological_process											owl:Class	
GO:0043894	biolink:NamedThing	acetyl-CoA synthetase acetyltransferase activity	Catalysis of the acetylation of residue Lys609 of the enzyme acetyl-CoA synthetase, using acetyl-CoA as substrate.	tmpzr1t_l9r_go_relaxed.owl	Pat|protein acetyltransferase activity|Pat enzyme													molecular_function											owl:Class	
GO:0016407	biolink:NamedThing	acetyltransferase activity	Catalysis of the transfer of an acetyl group to an acceptor molecule.	tmpzr1t_l9r_go_relaxed.owl	acetylase activity				Reactome:R-HSA-6805638|Reactome:R-HSA-6792712|Reactome:R-HSA-5682044|Reactome:R-HSA-73736|Reactome:R-HSA-5628871|Reactome:R-HSA-5660660									molecular_function											owl:Class	
GO:0008232	biolink:NamedThing	activator ecdysone receptor complex	A protein complex consisting of a heterodimer of Ecdysone receptor (EcR) and ultraspiracle (usp) bound to the ligand ecdysone, which activates transcription of target genes.	tmpzr1t_l9r_go_relaxed.owl	activator ecdysone receptor holocomplex													cellular_component											owl:Class	
GO:0008230	biolink:NamedThing	ecdysone receptor holocomplex	A heterodimeric complex containing the products of the insect genes Ecdysone receptor (EcR) and ultraspiracle (usp). Binding of ecdysone promotes association between the two subunits, and the receptor complex then initiates molting and metamorphosis by binding DNA and regulating the transcription of target genes.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0007506	biolink:NamedThing	gonadal mesoderm development	The process whose specific outcome is the progression of the gonadal mesoderm over time, from its formation to the mature structure. The gonadal mesoderm is the middle layer of the three primary germ layers of the embryo which will go on to form the gonads of the organism.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0007498	biolink:NamedThing	mesoderm development	The process whose specific outcome is the progression of the mesoderm over time, from its formation to the mature structure. The mesoderm is the middle germ layer that develops into muscle, bone, cartilage, blood and connective tissue.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0072103	biolink:NamedThing	glomerulus vasculature morphogenesis	The process in which the anatomical structures of the glomerulus vasculature are generated and organized. The glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the glomerulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-02-10T02:34:54Z					biological_process											owl:Class	
GO:0071252	biolink:NamedThing	cellular response to sulfur dioxide	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sulfur dioxide (SO2) stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-12-03T03:10:16Z					biological_process											owl:Class	
GO:1900073	biolink:NamedThing	regulation of neuromuscular synaptic transmission	Any process that modulates the frequency, rate or extent of neuromuscular synaptic transmission.	tmpzr1t_l9r_go_relaxed.owl								kmv	2012-01-26T10:14:10Z					biological_process											owl:Class	
GO:0050804	biolink:NamedThing	modulation of chemical synaptic transmission	Any process that modulates the frequency or amplitude of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse.  Amplitude, in this case, refers to the change in postsynaptic membrane potential due to a single instance of synaptic transmission.	tmpzr1t_l9r_go_relaxed.owl	regulation of synaptic transmission|modulation of synaptic transmission|regulation of chemical synaptic transmission													biological_process											owl:Class	
GO:0085033	biolink:NamedThing	induction by symbiont of host I-kappaB kinase/NF-kappaB cascade	Any process that activates or increases the frequency, rate or extent of host NF-kappaB-mediated signal transduction pathways during the host defense response. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	activation by symbiont of host I-kappaB kinase/NF-kappaB cascade|up regulation by symbiont of host I-kappaB kinase/NF-kappaB cascade|positive regulation by symbiont of host NF-kappaB-mediated signal transduction pathway|up-regulation by symbiont of host I-kappaB kinase/NF-kappaB cascade|positive regulation by symbiont of host I-kappaB kinase/NF-kappaB cascade|upregulation by symbiont of host I-kappaB kinase/NF-kappaB cascade|stimulation by symbiont of host I-kappaB kinase/NF-kappaB cascade|positive regulation by symbiont of nuclear factor kappa-light-chain-enhancer of activated B cells mediated signal transduction pathway							jl	2010-07-27T02:47:01Z					biological_process											owl:Class	
GO:0043123	biolink:NamedThing	positive regulation of I-kappaB kinase/NF-kappaB signaling	Any process that activates or increases the frequency, rate or extent of I-kappaB kinase/NF-kappaB signaling.	tmpzr1t_l9r_go_relaxed.owl	activation of I-kappaB kinase/NF-kappaB cascade|positive regulation of I-kappaB kinase/NF-kappaB cascade|up regulation of I-kappaB kinase/NF-kappaB cascade|stimulation of I-kappaB kinase/NF-kappaB cascade|up-regulation of I-kappaB kinase/NF-kappaB cascade|upregulation of I-kappaB kinase/NF-kappaB cascade													biological_process											owl:Class	
GO:0102301	biolink:NamedThing	gamma-linolenate elongase activity	Catalysis of the reaction: malonyl-CoA + gamma-linolenoyl-CoA + H+ = (8Z,11Z,14Z)-3-oxoicosa-8,11,14-trienoyl-CoA + coenzyme A + carbon dioxide.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-12777									molecular_function											owl:Class	
GO:2000741	biolink:NamedThing	positive regulation of mesenchymal stem cell differentiation	Any process that activates or increases the frequency, rate or extent of mesenchymal stem cell differentiation.	tmpzr1t_l9r_go_relaxed.owl								yaf	2011-06-14T02:31:34Z					biological_process											owl:Class	
GO:2000738	biolink:NamedThing	positive regulation of stem cell differentiation	Any process that activates or increases the frequency, rate or extent of stem cell differentiation.	tmpzr1t_l9r_go_relaxed.owl								yaf	2011-06-14T02:05:23Z					biological_process											owl:Class	
GO:0051782	biolink:NamedThing	negative regulation of cell division	Any process that stops, prevents, or reduces the frequency, rate or extent of cell division.	tmpzr1t_l9r_go_relaxed.owl	downregulation of cell division|down-regulation of cell division|inhibition of cell division|down regulation of cell division													biological_process											owl:Class	
GO:0033228	biolink:NamedThing	cysteine export across plasma membrane	The directed movement of cysteine from inside of a cell, across the plasma membrane and into the extracellular region.	tmpzr1t_l9r_go_relaxed.owl	cysteine export													biological_process											owl:Class	
GO:1903712	biolink:NamedThing	cysteine transmembrane transport	The directed movement of cysteine across a membrane.	tmpzr1t_l9r_go_relaxed.owl								vw	2014-12-06T08:15:06Z					biological_process											owl:Class	
GO:0045653	biolink:NamedThing	negative regulation of megakaryocyte differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of megakaryocyte differentiation.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of megakaryocyte differentiation|downregulation of megakaryocyte differentiation|inhibition of megakaryocyte differentiation|down regulation of megakaryocyte differentiation													biological_process											owl:Class	
GO:0045638	biolink:NamedThing	negative regulation of myeloid cell differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of myeloid cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	down regulation of myeloid cell differentiation|down-regulation of myeloid cell differentiation|inhibition of myeloid cell differentiation|downregulation of myeloid cell differentiation													biological_process											owl:Class	
GO:2000359	biolink:NamedThing	regulation of binding of sperm to zona pellucida	Any process that modulates the frequency, rate or extent of binding of sperm to the zona pellucida.	tmpzr1t_l9r_go_relaxed.owl	regulation of ZPG binding							yaf	2011-02-03T02:42:50Z					biological_process											owl:Class	
GO:0045683	biolink:NamedThing	negative regulation of epidermis development	Any process that stops, prevents, or reduces the frequency, rate or extent of epidermis development.	tmpzr1t_l9r_go_relaxed.owl	inhibition of epidermis development|negative regulation of epidermal development|down-regulation of epidermis development|negative regulation of hypodermis development|down regulation of epidermis development|downregulation of epidermis development													biological_process											owl:Class	
GO:0099050	biolink:NamedThing	vesicle scission	The membrane scission process that is the final step in the formation of a vesicle, leading to separation from its parent membrane. Vesicle scission involves the constriction of a neck-forming protein complex, consisting e.g. of dynamin, around the budded membrane, leading to vesicle closure during its separation from the parent membrane.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0033936	biolink:NamedThing	polymannuronate hydrolase activity	Catalysis of the endohydrolysis of the D-mannuronide linkages of polymannuronate.	tmpzr1t_l9r_go_relaxed.owl	polymannuronic acid polymerase activity|poly(mannuronide) mannuronohydrolase activity				EC:3.2.1.121|MetaCyc:3.2.1.121-RXN									molecular_function											owl:Class	
GO:0043292	biolink:NamedThing	contractile fiber	Fibers, composed of actin, myosin, and associated proteins, found in cells of smooth or striated muscle.	tmpzr1t_l9r_go_relaxed.owl	contractile fibre													cellular_component											owl:Class	
GO:0043232	biolink:NamedThing	intracellular non-membrane-bounded organelle	Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane and occurring within the cell. Includes ribosomes, the cytoskeleton and chromosomes.	tmpzr1t_l9r_go_relaxed.owl	intracellular non-membrane-enclosed organelle													cellular_component											owl:Class	
GO:0030093	biolink:NamedThing	chloroplast photosystem I	Photosystem located in the chloroplast that functions as a light-dependent plastocyanin-ferredoxin oxidoreductase, transferring electrons from plastocyanin to ferredoxin. An example of this is found in Arabidopsis thaliana.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0098807	biolink:NamedThing	chloroplast thylakoid membrane protein complex	A protein complex that is part of a chloroplast thylakoid membrane.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0016578	biolink:NamedThing	histone deubiquitination	The modification of histones by removal of ubiquitin groups.	tmpzr1t_l9r_go_relaxed.owl	histone deubiquitylation|histone deubiquitinylation													biological_process											owl:Class	
GO:0016579	biolink:NamedThing	protein deubiquitination	The removal of one or more ubiquitin groups from a protein.	tmpzr1t_l9r_go_relaxed.owl	protein deubiquitylation|deubiquitination|protein deubiquitinylation											GO:0006514		biological_process											owl:Class	
GO:0006688	biolink:NamedThing	glycosphingolipid biosynthetic process	The chemical reactions and pathways resulting in the formation of glycosphingolipid, a compound with residues of sphingoid and at least one monosaccharide.	tmpzr1t_l9r_go_relaxed.owl	glycosphingolipid biosynthesis|glycosphingolipid anabolism|glycosphingolipid formation|glycosphingolipid synthesis													biological_process											owl:Class	
GO:0030148	biolink:NamedThing	sphingolipid biosynthetic process	The chemical reactions and pathways resulting in the formation of sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid).	tmpzr1t_l9r_go_relaxed.owl	sphingolipid biosynthesis|sphingolipid synthesis|sphingolipid formation|sphingolipid anabolism				MetaCyc:PWY-5129									biological_process											owl:Class	
GO:0050903	biolink:NamedThing	leukocyte activation-dependent arrest	The formation of an integrin-dependent strong adhesive bond between leukocytes and blood vessel endothelial cells which is dependent on prior activation of the leukocyte and leads to the firm attachment of the leukocyte to the endothelial surface, typically the third step in cellular extravasation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0061756	biolink:NamedThing	leukocyte adhesion to vascular endothelial cell	The attachment of a leukocyte to vascular endothelial cell via adhesion molecules.	tmpzr1t_l9r_go_relaxed.owl								dph	2016-02-29T16:42:11Z					biological_process											owl:Class	
GO:0004783	biolink:NamedThing	sulfite reductase (NADPH) activity	Catalysis of the reaction: hydrogen sulfide + 3 NADP+ + 3 H2O = sulfite + 3 NADPH + 3 H+.	tmpzr1t_l9r_go_relaxed.owl	NADPH:sulfite reductase flavoprotein|sulphite reductase (NADPH) activity|NADPH-dependent sulfite reductase activity|sulfite (reduced nicotinamide adenine dinucleotide phosphate) reductase activity|NADPH-sulfite reductase activity|hydrogen-sulfide:NADP+ oxidoreductase activity|H2S-NADP oxidoreductase activity				EC:1.8.1.2|RHEA:13801|MetaCyc:SULFITE-REDUCT-RXN									molecular_function											owl:Class	
GO:0150036	biolink:NamedThing	regulation of trans-synaptic signaling by endocannabinoid, modulating synaptic transmission	Any process that modulates the frequency, rate or extent of trans-synaptic signaling by endocannabinoid, modulating synaptic transmission.	tmpzr1t_l9r_go_relaxed.owl						Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.		bc	2018-04-18T09:54:49Z					biological_process											owl:Class	
GO:0033900	biolink:NamedThing	ribonuclease F activity	Catalysis of the endonucleolytic cleavage of RNA precursor into two, leaving 5'-hydroxy and 3'-phosphate groups.	tmpzr1t_l9r_go_relaxed.owl	ribonuclease F (E. coli) activity|RNase F activity				MetaCyc:3.1.27.7-RXN|EC:3.1.27.7									molecular_function											owl:Class	
GO:0016892	biolink:NamedThing	endoribonuclease activity, producing 3'-phosphomonoesters	Catalysis of the hydrolysis of ester linkages within ribonucleic acids by creating internal breaks to yield 3'-phosphomonoesters.	tmpzr1t_l9r_go_relaxed.owl	endoribonuclease activity, producing other than 5'-phosphomonoesters				EC:3.1.27.-									molecular_function											owl:Class	
GO:0051633	biolink:NamedThing	positive regulation of acetylcholine uptake	Any process that activates or increases the frequency, rate or extent of the directed movement of acetylcholine into a cell.	tmpzr1t_l9r_go_relaxed.owl	stimulation of acetylcholine uptake|up regulation of acetylcholine uptake|activation of acetylcholine uptake|upregulation of acetylcholine uptake|up-regulation of acetylcholine uptake|positive regulation of acetylcholine import													biological_process											owl:Class	
GO:0032100	biolink:NamedThing	positive regulation of appetite	Any process that increases appetite.	tmpzr1t_l9r_go_relaxed.owl	stimulation of appetite|up regulation of appetite|appetite stimulation|positive regulation of hunger|upregulation of appetite|up-regulation of appetite|activation of appetite													biological_process											owl:Class	
GO:0032097	biolink:NamedThing	positive regulation of response to food	Any process that activates, maintains, or increases the rate of a response to a food stimulus.	tmpzr1t_l9r_go_relaxed.owl	stimulation of response to food|up-regulation of response to food|up regulation of response to food|upregulation of response to food|activation of response to food													biological_process											owl:Class	
GO:0032885	biolink:NamedThing	regulation of polysaccharide biosynthetic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of polysaccharides.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0090297	biolink:NamedThing	positive regulation of mitochondrial DNA replication	Any process that increases the rate, frequency or extent of the process in which new strands of DNA are synthesized in the mitochondrion.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of mitochondrial DNA synthesis							tb	2010-03-12T03:58:25Z					biological_process											owl:Class	
GO:0090296	biolink:NamedThing	regulation of mitochondrial DNA replication	Any process that modulates the rate, frequency or extent of the process in which new strands of DNA are synthesized in the mitochondrion.	tmpzr1t_l9r_go_relaxed.owl	regulation of mitochondrial DNA synthesis							tb	2010-03-12T03:58:25Z					biological_process											owl:Class	
GO:1905461	biolink:NamedThing	positive regulation of vascular associated smooth muscle cell apoptotic process	Any process that activates or increases the frequency, rate or extent of vascular associated smooth muscle cell apoptotic process.	tmpzr1t_l9r_go_relaxed.owl	upregulation of vascular associated smooth muscle cell apoptosis|upregulation of vascular smooth muscle cell apoptotic process|up regulation of vascular smooth muscle cell apoptotic process|up regulation of vascular associated smooth muscle cell apoptotic process|up-regulation of VSMC apoptotic process|up regulation of VSMC apoptosis|positive regulation of vascular smooth muscle cell apoptosis|positive regulation of VSMC apoptosis|up-regulation of vascular associated smooth muscle cell apoptotic process|upregulation of VSMC apoptosis|activation of vascular associated smooth muscle cell apoptosis|upregulation of vascular associated smooth muscle cell apoptotic process|activation of vascular smooth muscle cell apoptosis|activation of VSMC apoptotic process|activation of vascular associated smooth muscle cell apoptotic process|upregulation of vascular smooth muscle cell apoptosis|positive regulation of VSMC apoptotic process|up regulation of VSMC apoptotic process|up-regulation of vascular associated smooth muscle cell apoptosis|positive regulation of vascular smooth muscle cell apoptotic process|activation of VSMC apoptosis|up-regulation of VSMC apoptosis|up regulation of vascular associated smooth muscle cell apoptosis|up regulation of vascular smooth muscle cell apoptosis|up-regulation of vascular smooth muscle cell apoptotic process|upregulation of VSMC apoptotic process|positive regulation of vascular associated smooth muscle cell apoptosis|up-regulation of vascular smooth muscle cell apoptosis|activation of vascular smooth muscle cell apoptotic process							rph	2016-09-19T11:34:10Z					biological_process											owl:Class	
GO:1905459	biolink:NamedThing	regulation of vascular associated smooth muscle cell apoptotic process	Any process that modulates the frequency, rate or extent of vascular associated smooth muscle cell apoptotic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of VSMC apoptotic process|regulation of vascular associated smooth muscle cell apoptosis|regulation of VSMC apoptosis|regulation of vascular smooth muscle cell apoptosis|regulation of vascular smooth muscle cell apoptotic process							rph	2016-09-19T11:33:54Z					biological_process											owl:Class	
GO:0060332	biolink:NamedThing	positive regulation of response to interferon-gamma	Any process that increases the rate, frequency or extent of a response to interferon-gamma. Response to interferon gamma is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-gamma stimulus.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of response to type II interferon|positive regulation of response to type II IFN|positive regulation of response to immune interferon|positive regulation of response to gamma-interferon													biological_process											owl:Class	
GO:0075190	biolink:NamedThing	negative regulation of hyphopodium formation	Any process that stops, prevents, or reduces the frequency, rate or extent of symbiont hyphopodium formation on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of hyphopodium formation on or near host													biological_process											owl:Class	
GO:0075188	biolink:NamedThing	regulation of hyphopodium formation	Any process that modulates the frequency, rate or extent of symbiont hyphopodium formation on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	regulation of hyphopodium formation on or near host					Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products from the symbiont involved in this process.								biological_process											owl:Class	
GO:0047507	biolink:NamedThing	(deoxy)nucleoside-phosphate kinase activity	Catalysis of the reaction: ATP + deoxynucleoside phosphate = ADP + deoxynucleoside diphosphate.	tmpzr1t_l9r_go_relaxed.owl	deoxynucleoside monophosphate kinase activity|deoxynucleoside-5'-monophosphate kinase activity|deoxyribonucleoside monophosphokinase activity|ATP:deoxynucleoside-phosphate phosphotransferase activity				RHEA:11216|MetaCyc:DEOXYNUCLEOSIDE-PHOSPHATE-KINASE-RXN|EC:2.7.4.13									molecular_function											owl:Class	
GO:0042957	biolink:NamedThing	dextrin transmembrane transporter activity	Enables the transfer of dextrin, any one, or the mixture, of the intermediate polysaccharides formed during the hydrolysis of starch, which are dextrorotatory, soluble in water, and precipitable in alcohol, from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0015159	biolink:NamedThing	polysaccharide transmembrane transporter activity	Enables the transfer of polysaccharides from one side of a membrane to the other. A polysaccharide is a polymer of many (typically more than 10) monosaccharide residues linked glycosidically.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0060410	biolink:NamedThing	negative regulation of acetylcholine metabolic process	Any process that decreases the rate, frequency or extent of the chemical reactions and pathways involving acetylcholine, the acetic acid ester of the organic base choline. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0033239	biolink:NamedThing	negative regulation of cellular amine metabolic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving amines.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of amine metabolism													biological_process											owl:Class	
GO:0031524	biolink:NamedThing	menthol metabolic process	The chemical reactions and pathways involving menthol, the monoterpene 2-isopropyl-5-methylcyclohexanol.	tmpzr1t_l9r_go_relaxed.owl	menthol metabolism													biological_process											owl:Class	
GO:0039713	biolink:NamedThing	viral factory	An intracellular compartment in a host cell which increases the efficiency of viral replication, and shields the virus from host defenses. Viral factories can be either cytoplasmic or nuclear and often arise from extensive rearrangement of host cell cytoskeletal and/or cell membrane compartments.	tmpzr1t_l9r_go_relaxed.owl	virus factory				VZ:1951			bf	2013-12-19T14:53:47Z					cellular_component											owl:Class	
GO:0004905	biolink:NamedThing	type I interferon receptor activity	Combining with a type I interferon and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. Type I interferons include the interferon-alpha, beta, delta, epsilon, zeta, kappa, tau, and omega gene families.	tmpzr1t_l9r_go_relaxed.owl	type I IFN receptor activity|interferon-delta receptor activity|interferon-beta receptor activity|interferon-alpha/beta receptor activity|interferon-zeta receptor activity|interferon-tau receptor activity|interferon-epsilon receptor activity|interferon-omega receptor activity|interferon-alpha receptor activity|interferon-kappa receptor activity													molecular_function											owl:Class	
GO:0004904	biolink:NamedThing	interferon receptor activity	Combining with an interferon and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	IFN receptor activity													molecular_function											owl:Class	
GO:0015078	biolink:NamedThing	proton transmembrane transporter activity	Enables the transfer of a proton from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	proton transporter activity|hydrogen ion transmembrane transporter activity				Reactome:R-HSA-170026|Reactome:R-HSA-1222516|Reactome:R-HSA-74723|Reactome:R-HSA-164834|Reactome:R-HSA-917841									molecular_function											owl:Class	
GO:1990697	biolink:NamedThing	protein depalmitoleylation	The removal of palmitoleyl group, a 16-carbon monounsaturated fatty acid (C16:1), from a lipoprotein.	tmpzr1t_l9r_go_relaxed.owl								sp	2015-03-13T08:55:31Z					biological_process											owl:Class	
GO:0042159	biolink:NamedThing	lipoprotein catabolic process	The chemical reactions and pathways resulting in the breakdown of any conjugated, water-soluble protein in which the covalently attached nonprotein group consists of a lipid or lipids.	tmpzr1t_l9r_go_relaxed.owl	lipoprotein degradation|lipoprotein breakdown|lipoprotein catabolism													biological_process											owl:Class	
GO:0061428	biolink:NamedThing	negative regulation of transcription from RNA polymerase II promoter in response to hypoxia	Any process that decreases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a hypoxia stimulus.	tmpzr1t_l9r_go_relaxed.owl								dph	2012-02-06T09:26:05Z					biological_process											owl:Class	
GO:0097201	biolink:NamedThing	negative regulation of transcription from RNA polymerase II promoter in response to stress	Any process that decreases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).	tmpzr1t_l9r_go_relaxed.owl								pr	2011-12-14T09:16:22Z					biological_process											owl:Class	
GO:1904482	biolink:NamedThing	cellular response to tetrahydrofolate	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tetrahydrofolate stimulus.	tmpzr1t_l9r_go_relaxed.owl								hal	2015-07-14T14:49:23Z					biological_process											owl:Class	
GO:1903393	biolink:NamedThing	positive regulation of adherens junction organization	Any process that activates or increases the frequency, rate or extent of adherens junction organization.	tmpzr1t_l9r_go_relaxed.owl	activation of adherens junction organisation|up-regulation of adherens junction organization|up regulation of adherens junction organization|upregulation of adherens junction assembly and maintenance|up regulation of adherens junction organisation|positive regulation of adherens junction assembly and maintenance|up-regulation of adherens junction assembly and maintenance|upregulation of adherens junction organisation|activation of adherens junction assembly and maintenance|up-regulation of adherens junction organisation|activation of adherens junction organization|up regulation of adherens junction assembly and maintenance|positive regulation of adherens junction organisation|upregulation of adherens junction organization							als	2014-08-27T10:08:55Z					biological_process											owl:Class	
GO:0050295	biolink:NamedThing	steryl-beta-glucosidase activity	Catalysis of the reaction: cholesteryl-beta-D-glucoside + H(2)O = D-glucose + cholesterol.	tmpzr1t_l9r_go_relaxed.owl	steryl-b-glucosidase activity|cholesteryl-beta-D-glucoside glucohydrolase activity				EC:3.2.1.104|KEGG_REACTION:R01460|MetaCyc:STERYL-BETA-GLUCOSIDASE-RXN|RHEA:11956									molecular_function											owl:Class	
GO:0034634	biolink:NamedThing	glutathione transmembrane transporter activity	Enables the transfer of glutathione, the tripeptide glutamylcysteinylglycine, from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1900312	biolink:NamedThing	regulation of maltohexaose transport	Any process that modulates the frequency, rate or extent of maltohexaose transport.	tmpzr1t_l9r_go_relaxed.owl								tt	2012-04-05T07:59:18Z					biological_process											owl:Class	
GO:0008951	biolink:NamedThing	palmitoleoyl [acyl-carrier-protein]-dependent acyltransferase activity	Catalysis of the reaction: a palmitoleoyl-[acyl-carrier protein] + alpha-KDO-(2->4)-alpha-KDO-(2->6)-lipid IVA = KDO2-(palmitoleoyl)-lipid IVA + a holo-[acyl-carrier protein].	tmpzr1t_l9r_go_relaxed.owl	palmitoleoyl ACP-dependent acyltransferase activity				RHEA:44012|MetaCyc:PALMITOTRANS-RXN									molecular_function											owl:Class	
GO:0043533	biolink:NamedThing	inositol 1,3,4,5 tetrakisphosphate binding	Binding to inositol 1,3,4,5 tetrakisphosphate.	tmpzr1t_l9r_go_relaxed.owl	InsP4 binding|IP4 binding													molecular_function											owl:Class	
GO:0043178	biolink:NamedThing	alcohol binding	Binding to an alcohol, any of a class of alkyl compounds containing a hydroxyl group.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0048576	biolink:NamedThing	positive regulation of short-day photoperiodism, flowering	Any process that activates, maintains or increases short-day photoperiodism, where the response associated with the photoperiodism is flowering. Flowering is defined by the switch from the vegetative to the reproductive phase.	tmpzr1t_l9r_go_relaxed.owl	activation of short-day photoperiodism, flowering|up-regulation of short-day photoperiodism, flowering|stimulation of short-day photoperiodism, flowering|upregulation of short-day photoperiodism, flowering|up regulation of short-day photoperiodism, flowering													biological_process											owl:Class	
GO:0048582	biolink:NamedThing	positive regulation of post-embryonic development	Any process that activates or increases the frequency, rate or extent of post-embryonic development. Post-embryonic development is defined as the process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure.	tmpzr1t_l9r_go_relaxed.owl	upregulation of post-embryonic development|up-regulation of post-embryonic development|up regulation of post-embryonic development|stimulation of post-embryonic development|activation of post-embryonic development													biological_process											owl:Class	
GO:2000752	biolink:NamedThing	regulation of glucosylceramide catabolic process	Any process that modulates the frequency, rate or extent of glucosylceramide catabolic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of glucosylceramide degradation|regulation of glucosylceramide catabolism|regulation of glucosylceramide breakdown							rl	2011-06-16T03:12:04Z					biological_process											owl:Class	
GO:1905038	biolink:NamedThing	regulation of membrane lipid metabolic process	Any process that modulates the frequency, rate or extent of membrane lipid metabolic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of membrane lipid metabolism							tb	2016-03-08T20:41:32Z					biological_process											owl:Class	
GO:0019709	biolink:NamedThing	iron incorporation into iron-sulfur cluster via pentakis-L-cysteinyl L-histidino nickel tetrairon pentasulfide	The incorporation of iron into a nickel-iron-sulfur cluster via pentakis-L-cysteinyl L-histidino nickel tetrairon pentasulfide, found in carbon monoxide dehydrogenase.	tmpzr1t_l9r_go_relaxed.owl	iron incorporation into iron-sulphur cluster via pentakis-L-cysteinyl L-histidino nickel tetrairon pentasulphide				RESID:AA0310									biological_process											owl:Class	
GO:0019724	biolink:NamedThing	B cell mediated immunity	Any process involved with the carrying out of an immune response by a B cell, through, for instance, the production of antibodies or cytokines, or antigen presentation to T cells.	tmpzr1t_l9r_go_relaxed.owl	B-cell mediated immunity|B-lymphocyte mediated immune effector process|B lymphocyte mediated immune effector process|B-lymphocyte mediated immunity|B-cell mediated immune effector process|B lymphocyte mediated immunity													biological_process											owl:Class	
GO:0002460	biolink:NamedThing	adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	An immune response mediated by lymphocytes expressing specific receptors for antigen produced through a somatic diversification process that includes somatic recombination of germline gene segments encoding immunoglobulin superfamily domains. Recombined receptors for antigen encoded by immunoglobulin superfamily domains include T cell receptors and immunoglobulins (antibodies) produced by B cells. The first encounter with antigen elicits a primary immune response that is slow and not of great magnitude. T and B cells selected by antigen become activated and undergo clonal expansion. A fraction of antigen-reactive T and B cells become memory cells, whereas others differentiate into effector cells. The memory cells generated during the primary response enable a much faster and stronger secondary immune response upon subsequent exposures to the same antigen (immunological memory). An example of this is the adaptive immune response found in Mus musculus.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0043405	biolink:NamedThing	regulation of MAP kinase activity	Any process that modulates the frequency, rate or extent of MAP kinase activity.	tmpzr1t_l9r_go_relaxed.owl	Regulation of MAPK activity|regulation of mitogen activated protein kinase activity|regulation of mitogen-activated protein kinase activity													biological_process											owl:Class	
GO:1903683	biolink:NamedThing	positive regulation of epithelial cell-cell adhesion involved in epithelium migration	Any process that activates or increases the frequency, rate or extent of epithelial cell-cell adhesion involved in epithelium migration.	tmpzr1t_l9r_go_relaxed.owl	up regulation of epithelial cell-cell adhesion involved in epithelium migration|up-regulation of epithelial cell-cell adhesion involved in epithelium migration|upregulation of epithelial cell-cell adhesion involved in epithelium migration|activation of epithelial cell-cell adhesion involved in epithelium migration							als	2014-12-01T13:25:22Z					biological_process											owl:Class	
GO:1903681	biolink:NamedThing	regulation of epithelial cell-cell adhesion involved in epithelium migration	Any process that modulates the frequency, rate or extent of epithelial cell-cell adhesion involved in epithelium migration.	tmpzr1t_l9r_go_relaxed.owl								als	2014-12-01T13:25:05Z					biological_process											owl:Class	
GO:1904194	biolink:NamedThing	positive regulation of cholangiocyte apoptotic process	Any process that activates or increases the frequency, rate or extent of cholangiocyte apoptotic process.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of epithelial cell of bile duct apoptotic process|up-regulation of cholangiocyte apoptotic process|upregulation of epithelial cell of bile duct apoptotic process|up regulation of cholangiocyte apoptosis|upregulation of epithelial cell of bile duct apoptosis|positive regulation of cholangiocyte apoptosis|activation of cholangiocyte apoptosis|activation of cholangiocyte apoptotic process|upregulation of cholangiocyte apoptosis|up-regulation of epithelial cell of bile duct apoptosis|up-regulation of cholangiocyte apoptosis|activation of epithelial cell of bile duct apoptosis|activation of epithelial cell of bile duct apoptotic process|up regulation of cholangiocyte apoptotic process|positive regulation of epithelial cell of bile duct apoptosis|up regulation of epithelial cell of bile duct apoptotic process|upregulation of cholangiocyte apoptotic process|positive regulation of epithelial cell of bile duct apoptotic process|up regulation of epithelial cell of bile duct apoptosis							sl	2015-05-06T15:26:00Z					biological_process											owl:Class	
GO:1904192	biolink:NamedThing	regulation of cholangiocyte apoptotic process	Any process that modulates the frequency, rate or extent of cholangiocyte apoptotic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of epithelial cell of bile duct apoptotic process|regulation of cholangiocyte apoptosis|regulation of epithelial cell of bile duct apoptosis							sl	2015-05-06T15:25:48Z					biological_process											owl:Class	
GO:1901056	biolink:NamedThing	trimethylenediamine catabolic process	The chemical reactions and pathways resulting in the breakdown of trimethylenediamine.	tmpzr1t_l9r_go_relaxed.owl	trimethylenediamine catabolism|trimethylenediamine breakdown|trimethylenediamine degradation							yaf	2012-06-28T04:53:06Z					biological_process											owl:Class	
GO:0071414	biolink:NamedThing	cellular response to methotrexate	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methotrexate stimulus. Methotrexate is 4-amino-10-methylformic acid, a folic acid analogue that is a potent competitive inhibitor of dihydrofolate reductase.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-12-14T03:10:30Z					biological_process											owl:Class	
GO:0031427	biolink:NamedThing	response to methotrexate	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methotrexate stimulus. Methotrexate is 4-amino-10-methylformic acid, a folic acid analogue that is a potent competitive inhibitor of dihydrofolate reductase.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0032384	biolink:NamedThing	negative regulation of intracellular cholesterol transport	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of cholesterol within cells.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of intracellular cholesterol transport|down regulation of intracellular cholesterol transport|downregulation of intracellular cholesterol transport|inhibition of intracellular cholesterol transport													biological_process											owl:Class	
GO:0032375	biolink:NamedThing	negative regulation of cholesterol transport	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of cholesterol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of cholesterol transport|downregulation of cholesterol transport|inhibition of cholesterol transport|down regulation of cholesterol transport													biological_process											owl:Class	
GO:0004067	biolink:NamedThing	asparaginase activity	Catalysis of the reaction: L-asparagine + H2O = L-aspartate + NH3.	tmpzr1t_l9r_go_relaxed.owl	L-asparaginase activity|alpha-asparaginase activity|asparaginase II|colaspase activity|crasnitin|L-asparagine amidohydrolase activity|leunase activity|elspar				EC:3.5.1.1|RHEA:21016|MetaCyc:ASPARAGHYD-RXN|Reactome:R-HSA-6797627									molecular_function											owl:Class	
GO:0043895	biolink:NamedThing	cyclomaltodextrin glucanotransferase activity	Catalysis of the cyclization of part of a 1,4-alpha-D-glucan chain by formation of a 1,4-alpha-D-glucosidic bond.	tmpzr1t_l9r_go_relaxed.owl	alpha-cyclodextrin glucanotransferase|beta-cyclodextrin glucanotransferase|cyclodextrin glycosyltransferase|Bacillus macerans amylase|cyclodextrin glucanotransferase|1,4-alpha-D-glucan 4-alpha-D-(1,4-alpha-D-glucano)-transferase (cyclizing)|CGTase|gamma-cyclodextrin glycosyltransferase|konchizaimu|beta-cyclodextrin glycosyltransferase|alpha-1,4-glucan 4-glycosyltransferase, cyclizing|BMA|cyclomaltodextrin glucotransferase|neutral-cyclodextrin glycosyltransferase|alpha-cyclodextrin glycosyltransferase|cyclomaltodextrin glycosyltransferase				EC:2.4.1.19|MetaCyc:2.4.1.19-RXN									molecular_function											owl:Class	
GO:0047874	biolink:NamedThing	dolichyldiphosphatase activity	Catalysis of the reaction: dolichyl diphosphate + H2O = dolichyl phosphate + phosphate.	tmpzr1t_l9r_go_relaxed.owl	dolichyl-diphosphate phosphohydrolase activity|dolichyl pyrophosphatase activity|dolichol diphosphatase activity|dolichyl diphosphate phosphohydrolase activity				RHEA:14385|MetaCyc:DOLICHYLDIPHOSPHATASE-RXN|Reactome:R-HSA-446200|EC:3.6.1.43									molecular_function											owl:Class	
GO:0031756	biolink:NamedThing	Edg-3 sphingosine 1-phosphate receptor binding	Binding to an Edg-3 sphingosine 1-phosphate receptor.	tmpzr1t_l9r_go_relaxed.owl	Edg-3 sphingosine 1-phosphate receptor ligand													molecular_function											owl:Class	
GO:0048718	biolink:NamedThing	cibarial fish-trap bristle morphogenesis	The process in which the anatomical structures of a cibarial fish-trap bristle are generated and organized. A cibarial fish-trap bristle is a sensory bristle on the anterior plate of the cibarium.	tmpzr1t_l9r_go_relaxed.owl	fish trap bristle morphogenesis													biological_process											owl:Class	
GO:0008407	biolink:NamedThing	chaeta morphogenesis	The process in which the anatomical structures of the chaeta are generated and organized. A chaeta is a sensory multicellular cuticular outgrowth of a specifically differentiated cell.	tmpzr1t_l9r_go_relaxed.owl	bristle morphogenesis													biological_process											owl:Class	
GO:0031550	biolink:NamedThing	positive regulation of brain-derived neurotrophic factor receptor signaling pathway	Any process that activates or increases the frequency, rate or extent of signaling via the brain-derived neurotrophic factor receptor signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of BDNF receptor signaling pathway|positive regulation of brain-derived neurotrophic factor receptor signalling pathway|activation of brain-derived neurotrophic factor receptor signaling pathway|stimulation of brain-derived neurotrophic factor receptor signaling pathway|up regulation of brain-derived neurotrophic factor receptor signaling pathway|upregulation of brain-derived neurotrophic factor receptor signaling pathway|positive regulation of BDNF receptor signalling pathway|up-regulation of brain-derived neurotrophic factor receptor signaling pathway													biological_process											owl:Class	
GO:0090605	biolink:NamedThing	submerged biofilm formation	A process in which planktonically growing microorganisms aggregate and grow on solid substrates under the flow of a liquid and produce extracellular polymers that facilitate attachment and matrix formation, resulting in a change in the organisms' growth rate and gene transcription.	tmpzr1t_l9r_go_relaxed.owl	solid substrate biofilm formation							tb	2014-09-16T14:44:46Z					biological_process											owl:Class	
GO:0001932	biolink:NamedThing	regulation of protein phosphorylation	Any process that modulates the frequency, rate or extent of addition of phosphate groups into an amino acid in a protein.	tmpzr1t_l9r_go_relaxed.owl	regulation of protein amino acid phosphorylation													biological_process											owl:Class	
GO:0106023	biolink:NamedThing	regulation of pupariation	Any process that modulates the onset of pupariation.	tmpzr1t_l9r_go_relaxed.owl								hjd	2017-05-24T19:31:39Z					biological_process											owl:Class	
GO:0097668	biolink:NamedThing	SCF-Saf1/Pof9 ubiquitin ligase complex	An SCF ubiquitin ligase complex in which the F-box protein is Saf1 in S. cerevisiae (Pof9 in S. pombe).	tmpzr1t_l9r_go_relaxed.owl								pr	2014-10-06T10:28:30Z					cellular_component											owl:Class	
GO:1905362	biolink:NamedThing	negative regulation of endosomal vesicle fusion	Any process that stops, prevents or reduces the frequency, rate or extent of endosomal vesicle fusion.	tmpzr1t_l9r_go_relaxed.owl	downregulation of endosomal vesicle fusion|down-regulation of endosome vesicle fusion|down regulation of endosomal vesicle fusion|inhibition of endosomal vesicle fusion|down regulation of endosome vesicle fusion|down-regulation of endosomal vesicle fusion|inhibition of endosome vesicle fusion|downregulation of endosome vesicle fusion|negative regulation of endosome vesicle fusion							bc	2016-08-16T11:40:44Z					biological_process											owl:Class	
GO:1901262	biolink:NamedThing	negative regulation of sorocarp spore cell differentiation	Any process that stops, prevents or reduces the frequency, rate or extent of sorocarp spore cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	downregulation of sorocarp spore cell differentiation|inhibition of sorocarp spore cell differentiation|down regulation of sorocarp spore cell differentiation|down-regulation of sorocarp spore cell differentiation							jl	2012-08-15T09:44:50Z					biological_process											owl:Class	
GO:1990127	biolink:NamedThing	intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator	A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of osmotic stress, and ends when the execution phase of apoptosis is triggered.	tmpzr1t_l9r_go_relaxed.owl								pr	2013-06-19T13:55:06Z					biological_process											owl:Class	
GO:1900745	biolink:NamedThing	positive regulation of p38MAPK cascade	Any process that activates or increases the frequency, rate or extent of p38MAPK cascade.	tmpzr1t_l9r_go_relaxed.owl	activation of p38 MAPK cascade|upregulation of p38 MAPK cascade|activation of p38MAPK cascade|positive regulation of p38 cascade|positive regulation of p38 MAPK cascade|up regulation of p38MAPK cascade|upregulation of p38 cascade|up regulation of p38 MAPK cascade|up-regulation of p38MAPK cascade|activation of p38 cascade|up-regulation of p38 cascade|up-regulation of p38 MAPK cascade|upregulation of p38MAPK cascade|up regulation of p38 cascade							pm	2012-05-28T02:40:48Z					biological_process											owl:Class	
GO:0032836	biolink:NamedThing	glomerular basement membrane development	The process whose specific outcome is the progression of the glomerular basement membrane over time, from its formation to the mature structure. The glomerular basement membrane is the basal laminal portion of the glomerulus which performs the actual filtration.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0030198	biolink:NamedThing	extracellular matrix organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an extracellular matrix.	tmpzr1t_l9r_go_relaxed.owl	extracellular matrix organization and biogenesis|extracellular matrix organisation													biological_process											owl:Class	
GO:0051058	biolink:NamedThing	negative regulation of small GTPase mediated signal transduction	Any process that stops, prevents, or reduces the frequency, rate or extent of small GTPase mediated signal transduction.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of small GTPase mediated signal transduction|down regulation of small GTPase mediated signal transduction|downregulation of small GTPase mediated signal transduction|inhibition of small GTPase mediated signal transduction|negative regulation of small GTPase-mediated signal transduction													biological_process											owl:Class	
GO:0051056	biolink:NamedThing	regulation of small GTPase mediated signal transduction	Any process that modulates the frequency, rate or extent of small GTPase mediated signal transduction.	tmpzr1t_l9r_go_relaxed.owl	regulation of small GTPase-mediated signal transduction													biological_process											owl:Class	
GO:0006127	biolink:NamedThing	glycerophosphate shuttle	The process of transferring reducing equivalents from the cytosol into the mitochondria; NADH is used to synthesise glycerol 3-phosphate in the cytosol; this compound is then transported into the mitochondria where it is converted to dihydroxyacetone phosphate (DHAP) using FAD; DHAP then returns to the cytosol to complete the cycle.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:PWY-6118									biological_process											owl:Class	
GO:0046272	biolink:NamedThing	stilbene catabolic process	The chemical reactions and pathways resulting in the breakdown of stilbenes, a class of polyketide compounds formed from cinnamic acid and three molecules of malonyl CoA.	tmpzr1t_l9r_go_relaxed.owl	stilbene degradation|stilbene catabolism|stilbene breakdown													biological_process											owl:Class	
GO:1990579	biolink:NamedThing	peptidyl-serine trans-autophosphorylation	The phosphorylation of a peptidyl-serine to form peptidyl-O-phospho-L-serine on an identical protein. For example, phosphorylation by the other kinase within a homodimer.	tmpzr1t_l9r_go_relaxed.owl	serine transautophosphorylation|serine autophosphorylation in trans							bf	2014-12-09T09:20:08Z					biological_process											owl:Class	
GO:0080109	biolink:NamedThing	indole-3-acetonitrile nitrile hydratase activity	Catalysis of the reaction: indole-3-acetonitrile + H2O = indole-3-acetamide.	tmpzr1t_l9r_go_relaxed.owl					EC:4.2.1.84|KEGG_REACTION:R04020|MetaCyc:RXN-7567			dhl	2009-04-23T04:37:57Z					molecular_function											owl:Class	
GO:0018822	biolink:NamedThing	nitrile hydratase activity	Catalysis of the reaction: an aliphatic amide = a nitrile + H2O.	tmpzr1t_l9r_go_relaxed.owl	H-NHase activity|aliphatic nitrile hydratase activity|3-cyanopyridine hydratase activity|NHase activity|L-NHase activity|aliphatic-amide hydro-lyase (nitrile-forming)|nitrile hydro-lyase activity|acrylonitrile hydratase activity				UM-BBD_enzymeID:e0067|RHEA:12673|MetaCyc:NITRILE-HYDRATASE-RXN|EC:4.2.1.84									molecular_function											owl:Class	
GO:0046300	biolink:NamedThing	2,4-dichlorophenoxyacetic acid catabolic process	The chemical reactions and pathways resulting in the breakdown of 2,4-dichlorophenoxyacetic acid, a chlorinated phenoxy compound which functions as a systemic herbicide and is used to control many types of broadleaf weeds.	tmpzr1t_l9r_go_relaxed.owl	2,4-dichlorophenoxyacetic acid catabolism|2,4-dichlorophenoxyacetic acid breakdown|2,4-dichlorophenoxyacetic acid degradation													biological_process											owl:Class	
GO:0033353	biolink:NamedThing	S-adenosylmethionine cycle	A cyclic series of interconversions involving S-adenosylmethionine, S-adenosyl-L-homocysteine, L-cysteine, and L-methionine. Couples utilization of the methyl group of SAM with recycling of the homocysteinyl group and regeneration of methionine.	tmpzr1t_l9r_go_relaxed.owl	activated methyl cycle|SAM cycle				MetaCyc:PWY-5041									biological_process											owl:Class	
GO:0051960	biolink:NamedThing	regulation of nervous system development	Any process that modulates the frequency, rate or extent of nervous system development, the origin and formation of nervous tissue.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0060102	biolink:NamedThing	collagen and cuticulin-based cuticle extracellular matrix	A collagen and cuticulin-based noncellular, multilayered structure that is synthesized by an underlying ectodermal (hypodermal) cell layer. The cuticle serves essential functions in body morphology, locomotion, and environmental protection. An example of this component is found in Caenorhabditis elegans.	tmpzr1t_l9r_go_relaxed.owl	collagen and cuticulin-based exoskeleton extracellular matrix													cellular_component											owl:Class	
GO:0062023	biolink:NamedThing	collagen-containing extracellular matrix	An extracellular matrix consisting mainly of proteins (especially collagen) and glycosaminoglycans (mostly as proteoglycans) that provides not only essential physical scaffolding for the cellular constituents but can also initiate crucial biochemical and biomechanical cues required for tissue morphogenesis, differentiation and homeostasis. The components are secreted by cells in the vicinity and form a sheet underlying or overlying cells such as endothelial and epithelial cells.	tmpzr1t_l9r_go_relaxed.owl								dph	2018-04-13T12:47:21Z					cellular_component											owl:Class	
GO:0007264	biolink:NamedThing	small GTPase mediated signal transduction	Any series of molecular signals in which a small monomeric GTPase relays one or more of the signals.	tmpzr1t_l9r_go_relaxed.owl	small GTPase-mediated signal transduction													biological_process											owl:Class	
GO:0070538	biolink:NamedThing	oleic acid binding	Binding to oleic acid, the 18-carbon monounsaturated fatty acid (9Z)-octadec-9-enoic acid.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0005504	biolink:NamedThing	fatty acid binding	Binding to a fatty acid, an aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0072190	biolink:NamedThing	ureter urothelium development	The process whose specific outcome is the progression of the urothelium of the ureter over time, from its formation to the mature structure. The urothelium is an epithelium that makes up the epithelial tube of the ureter.	tmpzr1t_l9r_go_relaxed.owl	ureter epithelium development							mah	2010-03-01T01:46:31Z					biological_process											owl:Class	
GO:0060429	biolink:NamedThing	epithelium development	The process whose specific outcome is the progression of an epithelium over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0086067	biolink:NamedThing	AV node cell to bundle of His cell communication	The process that mediates interactions between an AV node cell and its surroundings that contributes to the process of the AV node cell communicating with a bundle of His cell in cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.	tmpzr1t_l9r_go_relaxed.owl	atrioventricular node cell to bundle of His cell communication							dph	2011-11-22T09:11:44Z					biological_process											owl:Class	
GO:0086065	biolink:NamedThing	cell communication involved in cardiac conduction	Any process that mediates interactions between a cell and its surroundings that contributes to the process of cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.	tmpzr1t_l9r_go_relaxed.owl								dph	2011-11-22T08:57:02Z					biological_process											owl:Class	
GO:0051167	biolink:NamedThing	xylulose 5-phosphate metabolic process	The chemical reactions and pathways involving xylulose 5-phosphate, a derivative of the ketopentose xylulose phosphorylated at the 5 carbon; it is an intermediate in the pentose phosphate pathway.	tmpzr1t_l9r_go_relaxed.owl	xylulose-5-phosphate metabolism|D-xylulose 5-phosphate metabolism|xylulose 5-phosphate metabolism|xylulose-5-phosphate metabolic process|D-xylulose-5-phosphate metabolic process|D-xylulose 5-phosphate metabolic process|D-xylulose-5-phosphate metabolism													biological_process											owl:Class	
GO:2001006	biolink:NamedThing	regulation of cellulose biosynthetic process	Any process that modulates the frequency, rate or extent of cellulose biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of cellulose synthesis|regulation of cellulose biosynthesis|regulation of cellulose formation|regulation of cellulose anabolism							tt	2011-08-08T08:42:17Z					biological_process											owl:Class	
GO:1905049	biolink:NamedThing	negative regulation of metallopeptidase activity	Any process that stops, prevents or reduces the frequency, rate or extent of metallopeptidase activity.	tmpzr1t_l9r_go_relaxed.owl	downregulation of metallopeptidase activity|inhibition of metalloproteinase activity|inhibition of metallopeptidase activity|down-regulation of metallopeptidase activity|down-regulation of metalloprotease activity|negative regulation of metalloprotease activity|down regulation of metallopeptidase activity|down regulation of metalloproteinase activity|downregulation of metalloproteinase activity|down-regulation of metalloproteinase activity|down regulation of metalloprotease activity|inhibition of metalloprotease activity|downregulation of metalloprotease activity|negative regulation of metalloproteinase activity							mm2	2016-03-15T16:44:37Z					biological_process											owl:Class	
GO:0010466	biolink:NamedThing	negative regulation of peptidase activity	Any process that stops or reduces the rate of peptidase activity, the hydrolysis of peptide bonds within proteins.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1904846	biolink:NamedThing	negative regulation of establishment of bipolar cell polarity	Any process that stops, prevents or reduces the frequency, rate or extent of establishment of bipolar cell polarity.	tmpzr1t_l9r_go_relaxed.owl	downregulation of establishment of bipolar cell polarity|down-regulation of establishment of bipolar cell polarity|down regulation of establishment of bipolar cell polarity|inhibition of establishment of bipolar cell polarity							al	2015-12-08T15:06:30Z					biological_process											owl:Class	
GO:0061172	biolink:NamedThing	regulation of establishment of bipolar cell polarity	Any process that modulates the rate, frequency or extent of the establishment of bipolar cell polarity. Bipolar organization is the organization that is a mirror image along an axis from a plane.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-06-30T08:51:27Z					biological_process											owl:Class	
GO:0001913	biolink:NamedThing	T cell mediated cytotoxicity	The directed killing of a target cell by a T cell through the release of granules containing cytotoxic mediators or through the engagement of death receptors.	tmpzr1t_l9r_go_relaxed.owl	T cell mediated cytolysis|T-cell mediated cytotoxicity|T-cell mediated cell death|T-cell mediated cell killing|T cell mediated cell death|T-lymphocyte mediated cytotoxicity|T cell mediated cell killing|T-cell mediated apoptosis|T lymphocyte mediated cytotoxicity|T cell mediated apoptosis					Note that either or both mechanisms mentioned in the definition may be used in this process. Note that both granule release and the engagement of death receptors on target cells result in the induction of apoptosis in the target cell. Note that both CD4 and CD8 positive T cells can mediate apoptosis of target cells, independently of their definition as 'helper' T cells or not.								biological_process											owl:Class	
GO:0001909	biolink:NamedThing	leukocyte mediated cytotoxicity	The directed killing of a target cell by a leukocyte.	tmpzr1t_l9r_go_relaxed.owl	immune cell mediated cell death|immune cell mediated cytotoxicity|leucocyte mediated cytotoxicity|immune cell mediated cell killing					Note that this term and its children describe contact-dependent killing of target cells by lymphocytes and myeloid cells of the immune system.								biological_process											owl:Class	
GO:0097423	biolink:NamedThing	mitochondrion-associated adherens complex	An organelle arrangement comprised of the following elements: a mitochondrion positioned near the presynaptic membrane; an electron-dense mitochondrial plaque adjacent to the outer mitochondrial membrane that faces the presynaptic membrane; filament-like elements appearing to link the mitochondrial plaque to a cell-cell junction region (sometimes termed punctum adherens); tubular or vesicular-appearing membrane (also called vesicular chain) interposed among the filaments. Mitochondrion-associated adherens complexes were initially described in the dorsal horn of the spinal cord. They are found in calyces and other large terminals of the auditory brainstem, and in a variety of mammalian species including humans.	tmpzr1t_l9r_go_relaxed.owl	mitochondrial adhaerens complex|MAC				NIF_Subcellular:sao1933817066			pr	2012-11-07T13:38:50Z					cellular_component											owl:Class	
GO:0006853	biolink:NamedThing	carnitine shuttle	The transfer of acyl groups to and from acyl-CoA molecules to form O-acylcarnitine, which can exchange across the mitochondrial inner membrane with unacylated carnitine.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Carnitine#Role_in_fatty_acid_metabolism	See also the cellular component term 'mitochondrial inner membrane ; GO:0005743'.								biological_process											owl:Class	
GO:0045198	biolink:NamedThing	establishment of epithelial cell apical/basal polarity	The specification and formation of the apicobasal polarity of an epithelial cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0090162	biolink:NamedThing	establishment of epithelial cell polarity	The specification and formation of anisotropic intracellular organization of an epithelial cell.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-12-08T08:58:27Z					biological_process											owl:Class	
GO:2000119	biolink:NamedThing	negative regulation of sodium-dependent phosphate transport	Any process that stops, prevents, or reduces the frequency, rate or extent of sodium-dependent phosphate transport.	tmpzr1t_l9r_go_relaxed.owl								jl	2010-09-23T01:35:03Z					biological_process											owl:Class	
GO:2000118	biolink:NamedThing	regulation of sodium-dependent phosphate transport	Any process that modulates the frequency, rate or extent of sodium-dependent phosphate transport.	tmpzr1t_l9r_go_relaxed.owl								jl	2010-09-23T01:34:59Z					biological_process											owl:Class	
GO:0062140	biolink:NamedThing	hyphae septin collar	A septin collar in pathogenic fungi involved in the constriction of hyphae at the plant plasmodesma enabling penetration of an adjacent cell.	tmpzr1t_l9r_go_relaxed.owl	septin collar of invasive hyphae	https://github.com/geneontology/go-ontology/issues/19013						dph	2019-08-06T14:31:04Z					cellular_component											owl:Class	
GO:0032173	biolink:NamedThing	septin collar	A tubular, hourglass-shaped structure composed of highly ordered arrays of septin filaments; in budding yeast cells, the septin collar forms from the initial septin ring by expanding into the daughter cell.	tmpzr1t_l9r_go_relaxed.owl	septin hourglass	https://github.com/geneontology/go-ontology/issues/19534												cellular_component											owl:Class	
GO:0002733	biolink:NamedThing	regulation of myeloid dendritic cell cytokine production	Any process that modulates the frequency, rate, or extent of myeloid dendritic cell cytokine production.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0002886	biolink:NamedThing	regulation of myeloid leukocyte mediated immunity	Any process that modulates the frequency, rate, or extent of myeloid leukocyte mediated immunity.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0035178	biolink:NamedThing	turning behavior	Fine-tuning the spatial position of an organism in response to variability in their environment. For example, reorientation of an organism in the direction of a food source.	tmpzr1t_l9r_go_relaxed.owl	turning behaviour													biological_process											owl:Class	
GO:0007626	biolink:NamedThing	locomotory behavior	The specific movement from place to place of an organism in response to external or internal stimuli. Locomotion of a whole organism in a manner dependent upon some combination of that organism's internal state and external conditions.	tmpzr1t_l9r_go_relaxed.owl	locomotion in response to stimulus|behavior via locomotion|locomotory behavioral response to stimulus|locomotory behaviour|locomotory behavioural response to stimulus													biological_process											owl:Class	
GO:0045602	biolink:NamedThing	negative regulation of endothelial cell differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of endothelial cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	inhibition of endothelial cell differentiation|downregulation of endothelial cell differentiation|down-regulation of endothelial cell differentiation|down regulation of endothelial cell differentiation													biological_process											owl:Class	
GO:0010061	biolink:NamedThing	regulation of trichoblast fate specification	Any process that modulates trichoblast fate specification.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:2000067	biolink:NamedThing	regulation of root morphogenesis	Any process that modulates the frequency, rate or extent of root morphogenesis.	tmpzr1t_l9r_go_relaxed.owl								tb	2010-08-23T09:25:13Z					biological_process											owl:Class	
GO:0010278	biolink:NamedThing	chloroplast outer membrane translocon	The protein transport machinery of the chloroplast outer membrane that contains at least three components Toc159, Toc75 and Toc34, interacts with precursor proteins which are imported into the chloroplast in a GTP dependant manner.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0018902	biolink:NamedThing	1,3-dichloro-2-propanol metabolic process	The chemical reactions and pathways involving 1,3-dichloro-2-propanol (DCP), a halohydrin suspected of being carcinogenic, mutagenic and genotoxic. DCP is used as a general solvent, as an intermediate in organic synthesis and in paints, varnishes, lacquers, water colors, binders and photographic lacquers.	tmpzr1t_l9r_go_relaxed.owl	DCP metabolism|1,3-dichloro-2-propanol metabolism|DCP metabolic process				UM-BBD_pathwayID:dcp									biological_process											owl:Class	
GO:1900469	biolink:NamedThing	negative regulation of phosphatidylserine biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of phosphatidylserine biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of phosphatidylserine biosynthesis|negative regulation of phosphatidylserine synthesis|negative regulation of phosphatidylserine anabolism|downregulation of phosphatidylserine anabolism|downregulation of phosphatidylserine biosynthesis|down-regulation of phosphatidylserine synthesis|inhibition of phosphatidylserine formation|negative regulation of phosphatidylserine formation|downregulation of phosphatidylserine biosynthetic process|inhibition of phosphatidylserine biosynthetic process|inhibition of phosphatidylserine synthesis|downregulation of phosphatidylserine formation|negative regulation of phosphatidylserine biosynthesis|down regulation of phosphatidylserine synthesis|down regulation of phosphatidylserine biosynthetic process|down-regulation of phosphatidylserine formation|down regulation of phosphatidylserine formation|inhibition of phosphatidylserine biosynthesis|down regulation of phosphatidylserine anabolism|inhibition of phosphatidylserine anabolism|downregulation of phosphatidylserine synthesis|down-regulation of phosphatidylserine biosynthetic process|down regulation of phosphatidylserine biosynthesis|down-regulation of phosphatidylserine anabolism							dgf	2012-05-01T08:01:11Z					biological_process											owl:Class	
GO:0150180	biolink:NamedThing	negative regulation of phosphatidylserine metabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of phosphatidylserine metabolic process.	tmpzr1t_l9r_go_relaxed.owl								bc	2020-01-21T14:06:06Z					biological_process											owl:Class	
GO:1990113	biolink:NamedThing	RNA polymerase I assembly	The aggregation, arrangement and bonding together of a set of components to form the eukaryotic RNA polymerase I complex.	tmpzr1t_l9r_go_relaxed.owl	DNA-directed RNA polymerase I complex assembly|RNA Polymerase I complex assembly							rb	2013-05-31T21:44:41Z					biological_process											owl:Class	
GO:1900564	biolink:NamedThing	chanoclavine-I metabolic process	The chemical reactions and pathways involving chanoclavine-I.	tmpzr1t_l9r_go_relaxed.owl	chanoclavine-I metabolism							di	2012-05-15T06:30:25Z					biological_process											owl:Class	
GO:0060878	biolink:NamedThing	pouch outgrowth involved in semicircular canal formation	The morphogenetic process in which an epithelial sheet bends along a linear axis and gives rise to a pouch that will form a semicircular canal.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-08-13T10:01:01Z					biological_process											owl:Class	
GO:0051564	biolink:NamedThing	positive regulation of smooth endoplasmic reticulum calcium ion concentration	Any process that increases the concentration of calcium ions in the smooth endoplasmic reticulum.	tmpzr1t_l9r_go_relaxed.owl	smooth endoplasmic reticulum calcium ion concentration elevation|elevation of smooth ER calcium ion concentration|elevation of smooth endoplasmic reticulum calcium ion concentration|elevation of calcium ion concentration in smooth endoplasmic reticulum													biological_process											owl:Class	
GO:0032470	biolink:NamedThing	positive regulation of endoplasmic reticulum calcium ion concentration	Any process that increases the concentration of calcium ions in the endoplasmic reticulum.	tmpzr1t_l9r_go_relaxed.owl	elevation of endoplasmic reticulum calcium ion concentration|endoplasmic reticulum calcium ion concentration elevation|elevation of ER calcium ion concentration|elevation of calcium ion concentration in endoplasmic reticulum													biological_process											owl:Class	
GO:0045818	biolink:NamedThing	negative regulation of glycogen catabolic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glycogen.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of glycogenolysis|negative regulation of glycogen catabolism|negative regulation of glycogen degradation|inhibition of glycogen catabolic process|negative regulation of glycogen breakdown|down regulation of glycogen catabolic process|down-regulation of glycogen catabolic process|downregulation of glycogen catabolic process													biological_process											owl:Class	
GO:1901337	biolink:NamedThing	thioester transport	The directed movement of a thioester into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl								bf	2012-09-03T13:14:44Z					biological_process											owl:Class	
GO:0034679	biolink:NamedThing	integrin alpha9-beta1 complex	An integrin complex that comprises one alpha9 subunit and one beta1 subunit.	tmpzr1t_l9r_go_relaxed.owl	ITGA9-ITGB1 complex|alpha9-beta1 integrin complex													cellular_component											owl:Class	
GO:1900310	biolink:NamedThing	negative regulation of maltoheptaose metabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of maltoheptaose metabolic process.	tmpzr1t_l9r_go_relaxed.owl	inhibition of maltoheptaose metabolism|negative regulation of maltoheptaose metabolism|down-regulation of maltoheptaose metabolism|inhibition of maltoheptaose metabolic process|down regulation of maltoheptaose metabolic process|down-regulation of maltoheptaose metabolic process|downregulation of maltoheptaose metabolic process|downregulation of maltoheptaose metabolism|down regulation of maltoheptaose metabolism							tt	2012-04-05T07:58:58Z					biological_process											owl:Class	
GO:1900309	biolink:NamedThing	regulation of maltoheptaose metabolic process	Any process that modulates the frequency, rate or extent of maltoheptaose metabolic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of maltoheptaose metabolism							tt	2012-04-05T07:58:48Z					biological_process											owl:Class	
GO:2000684	biolink:NamedThing	negative regulation of cellular response to X-ray	Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to X-ray.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of cellular response to X-ray radiation stimulus							yaf	2011-05-10T01:40:45Z					biological_process											owl:Class	
GO:2000683	biolink:NamedThing	regulation of cellular response to X-ray	Any process that modulates the frequency, rate or extent of cellular response to X-ray.	tmpzr1t_l9r_go_relaxed.owl	regulation of cellular response to X-ray radiation stimulus							yaf	2011-05-10T01:40:41Z					biological_process											owl:Class	
GO:0046886	biolink:NamedThing	positive regulation of hormone biosynthetic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hormones.	tmpzr1t_l9r_go_relaxed.owl	up regulation of hormone biosynthetic process|stimulation of hormone biosynthetic process|upregulation of hormone biosynthetic process|positive regulation of hormone anabolism|positive regulation of hormone synthesis|positive regulation of hormone biosynthesis|positive regulation of hormone formation|up-regulation of hormone biosynthetic process|activation of hormone biosynthetic process													biological_process											owl:Class	
GO:0033420	biolink:NamedThing	CUG codon-amino acid adaptor activity	A triplet codon-amino acid adaptor activity that recognizes a CUG codon.	tmpzr1t_l9r_go_relaxed.owl	leucine tRNA|CTG codon-amino acid adaptor activity					Note that in the standard genetic code, CTG codes for leucine.								molecular_function											owl:Class	
GO:0048804	biolink:NamedThing	imaginal disc-derived female genitalia morphogenesis	The process in which the anatomical structures of female genitalia are generated and organized from the genital disc.	tmpzr1t_l9r_go_relaxed.owl	female genital morphogenesis													biological_process											owl:Class	
GO:0048805	biolink:NamedThing	imaginal disc-derived genitalia morphogenesis	The process in which the anatomical structures of genitalia are generated and organized from the genital imaginal disc.	tmpzr1t_l9r_go_relaxed.owl	genital morphogenesis													biological_process											owl:Class	
GO:0045782	biolink:NamedThing	positive regulation of cell budding	Any process that activates or increases the frequency, rate or extent of cell budding.	tmpzr1t_l9r_go_relaxed.owl	up regulation of cell budding|stimulation of cell budding|activation of cell budding|positive regulation of budding|up-regulation of cell budding|upregulation of cell budding													biological_process											owl:Class	
GO:0002411	biolink:NamedThing	T cell tolerance induction to tumor cell	A process of tolerance induction dependent on T cells which leads to immunological tolerance of a tumor.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1900277	biolink:NamedThing	negative regulation of proteinase activated receptor activity	Any process that stops, prevents or reduces the frequency, rate or extent of proteinase activated receptor activity.	tmpzr1t_l9r_go_relaxed.owl	downregulation of proteinase activated receptor activity|down-regulation of proteinase activated receptor activity|inhibition of proteinase activated receptor activity|down regulation of proteinase activated receptor activity							rl	2012-04-04T01:31:29Z					biological_process											owl:Class	
GO:0060034	biolink:NamedThing	notochord cell differentiation	The process in which relatively unspecialized cells acquire specialized structural and/or functional features cells that make up the notochord. Differentiation includes the processes involved in commitment of a cell to a notochord cell fate.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0062109	biolink:NamedThing	regulation of DNA recombinase disassembly	Any process that modulates the rate, frequency or extent of DNA recombinase disassembly, the disaggregation of a DNA recombinase complex into its constituent components.	tmpzr1t_l9r_go_relaxed.owl								dph	2019-02-05T13:53:19Z					biological_process											owl:Class	
GO:0048236	biolink:NamedThing	plant-type sporogenesis	The formation of plant spores derived from the products of meiosis. The spore gives rise to gametophytes.	tmpzr1t_l9r_go_relaxed.owl	plant spore formation													biological_process											owl:Class	
GO:0010105	biolink:NamedThing	negative regulation of ethylene-activated signaling pathway	Any process that stops or prevents ethylene (ethene) signal transduction.	tmpzr1t_l9r_go_relaxed.owl	down regulation of ethylene mediated signaling pathway|negative regulation of ethene mediated signalling pathway|negative regulation of ethylene mediated signalling pathway|downregulation of ethylene mediated signaling pathway|negative regulation of ethene mediated signaling pathway|inhibition of ethylene mediated signaling pathway|down-regulation of ethylene mediated signaling pathway|negative regulation of ethylene mediated signaling pathway													biological_process											owl:Class	
GO:0070298	biolink:NamedThing	negative regulation of phosphorelay signal transduction system	Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction via a phosphorelay signal transduction system.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of histidyl-aspartyl phosphorelay|down-regulation of two-component signal transduction|inhibition of two-component signal transduction|down regulation of two-component signal transduction|downregulation of two-component signal transduction|negative regulation of two-component signal transduction system (phosphorelay)													biological_process											owl:Class	
GO:0060056	biolink:NamedThing	mammary gland involution	The tissue remodeling that removes differentiated mammary epithelia during weaning.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0048771	biolink:NamedThing	tissue remodeling	The reorganization or renovation of existing tissues. This process can either change the characteristics of a tissue such as in blood vessel remodeling, or result in the dynamic equilibrium of a tissue such as in bone remodeling.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0090103	biolink:NamedThing	cochlea morphogenesis	The process in which the cochlea is generated and organized.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-11-18T11:45:11Z					biological_process											owl:Class	
GO:0010482	biolink:NamedThing	regulation of epidermal cell division	Any process that modulates the frequency, rate or extent of the physical partitioning and separation of an epidermal cell into daughter cells. An epidermal cell is any of the cells that make up the epidermis.	tmpzr1t_l9r_go_relaxed.owl	regulation of hypodermal cell division													biological_process											owl:Class	
GO:0046873	biolink:NamedThing	metal ion transmembrane transporter activity	Enables the transfer of metal ions from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	low affinity metal ion uptake transporter activity|high affinity metal ion uptake transporter activity|heavy metal ion porter activity|heavy metal-exporting ATPase activity|heavy metal ion:hydrogen symporter activity|heavy metal ion transporter activity													molecular_function											owl:Class	
GO:0061804	biolink:NamedThing	mitotic spindle formation (spindle phase one)	The cell cycle process in which the distance is lengthened between poles of the mitotic spindle during mitotic prophase.	tmpzr1t_l9r_go_relaxed.owl	mitotic spindle elongation during prophase and prometaphase|mitotic spindle elongation during mitotic prophase|mitotic spindle elongation during prophase							dph	2016-11-06T23:08:01Z					biological_process											owl:Class	
GO:0007051	biolink:NamedThing	spindle organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the spindle, the array of microtubules and associated molecules that forms between opposite poles of a eukaryotic cell during DNA segregation and serves to move the duplicated chromosomes apart.	tmpzr1t_l9r_go_relaxed.owl	spindle organisation|spindle stabilization|spindle organization and biogenesis											GO:0043146		biological_process											owl:Class	
GO:1990303	biolink:NamedThing	UBR1-RAD6 ubiquitin ligase complex	A ubiquitin ligase complex consisting of UBR1 and RAD6 components. It polyubiquitinates proteins containing non-acetylated N-terminal residues causing their subsequent degradation by the proteasome as part of the Ac/N-End Rule pathway. It recognizes non-acetylated N-terminal methionine if it is followed by a hydrophobic residue. Additionally, it acts in an N-end rule independent manner as a component of a novel quality control pathway for proteins synthesized on cytosolic ribosomes.	tmpzr1t_l9r_go_relaxed.owl	UBR1-RAD6 complex					This complex has been identified in Saccharomyces cerevisiae (P19812) - see PMID:19531475 (inferred from direct assay).		bhm	2014-03-03T21:43:49Z					cellular_component											owl:Class	
GO:0060339	biolink:NamedThing	negative regulation of type I interferon-mediated signaling pathway	Any process that decreases the rate, frequency or extent of a type I interferon-mediated signaling pathway. A type I interferon-mediated signaling pathway is the series of molecular events generated as a consequence of a type I interferon binding to a cell surface receptor.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of type I interferon-mediated signalling pathway													biological_process											owl:Class	
GO:0090109	biolink:NamedThing	regulation of cell-substrate junction assembly	Any process that modulates the rate, frequency, or extent of cell-substrate junction assembly. Cell-substrate junction assembly is the aggregation, arrangement and bonding together of a set of components to form a junction between a cell and its substrate.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-11-25T11:00:58Z					biological_process											owl:Class	
GO:0086083	biolink:NamedThing	cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication	Binding to a protein or protein complex that results in the connection of a bundle of His cell with a Purkinje myocyte and contributes to the communication between the two cells.	tmpzr1t_l9r_go_relaxed.owl								dph	2011-11-22T11:11:03Z					molecular_function											owl:Class	
GO:0072072	biolink:NamedThing	kidney stroma development	The process whose specific outcome is the progression of the kidney stroma over time, from its formation to the mature structure. The kidney stroma is the mesenchyme of the mature kidney.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-01-25T04:35:36Z					biological_process											owl:Class	
GO:0072074	biolink:NamedThing	kidney mesenchyme development	The biological process whose specific outcome is the progression of a kidney mesenchyme from an initial condition to its mature state. This process begins with the formation of kidney mesenchyme and ends with the mature structure. Kidney mesenchyme is the tissue made up of loosely connected mesenchymal cells in the kidney.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-01-25T04:39:04Z					biological_process											owl:Class	
GO:0009439	biolink:NamedThing	cyanate metabolic process	The chemical reactions and pathways involving cyanate, NCO-, the anion of cyanic acid.	tmpzr1t_l9r_go_relaxed.owl	cyanate metabolism				MetaCyc:CYANCAT-PWY									biological_process											owl:Class	
GO:0048247	biolink:NamedThing	lymphocyte chemotaxis	The directed movement of a lymphocyte in response to an external stimulus.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0072676	biolink:NamedThing	lymphocyte migration	The movement of a lymphocyte within or between different tissues and organs of the body.	tmpzr1t_l9r_go_relaxed.owl								mah	2011-02-22T03:38:12Z					biological_process											owl:Class	
GO:1990332	biolink:NamedThing	Ire1 complex	A type-I transmembrane protein complex located in the endoplasmic reticulum (ER) consisting of an IRE1-IRE1 dimer, which forms in response to the accumulation of unfolded protein in the ER. The dimeric complex has endoribonuclease (RNase) activity and evokes the unfolded protein response (UPR) by cleaving an intron of a mRNA coding for the transcription factor HAC1 in yeast or XBP1 in mammals; the complex cleaves a single phosphodiester bond in each of two RNA hairpins (with non-specific base paired stems and loops of consensus sequence CNCNNGN, where N is any base) to remove an intervening intron from the target transcript.	tmpzr1t_l9r_go_relaxed.owl	IRE1 dimer|ERN1 complex					An example of this is Ire1 in Escherichia coli (P32361) in PMID:18191223 (inferred from direct assay).		bhm	2014-03-17T10:46:58Z					cellular_component											owl:Class	
GO:0042321	biolink:NamedThing	negative regulation of circadian sleep/wake cycle, sleep	Any process that stops, prevents or reduces the duration or quality of sleep, a readily reversible state of reduced awareness and metabolic activity that occurs periodically in many animals.	tmpzr1t_l9r_go_relaxed.owl	downregulation of circadian sleep/wake cycle, sleep|down regulation of circadian sleep/wake cycle, sleep|negative regulation of sleep|down-regulation of circadian sleep/wake cycle, sleep|inhibition of circadian sleep/wake cycle, sleep													biological_process											owl:Class	
GO:0033396	biolink:NamedThing	beta-alanine biosynthetic process via 3-ureidopropionate	The chemical reactions and pathways resulting in the formation of beta-alanine via the intermediate 3-ureidopropionate.	tmpzr1t_l9r_go_relaxed.owl	beta-alanine anabolism via 3-ureidopropionate|beta-alanine formation via 3-ureidopropionate|beta-alanine synthesis via 3-ureidopropionate				MetaCyc:PWY-3982									biological_process											owl:Class	
GO:0019483	biolink:NamedThing	beta-alanine biosynthetic process	The chemical reactions and pathways resulting in the formation of beta-alanine (3-aminopropanoic acid), an achiral amino acid and an isomer of alanine. It occurs free (e.g. in brain) and in combination (e.g. in pantothenate) but it is not a constituent of proteins.	tmpzr1t_l9r_go_relaxed.owl	beta-alanine formation|beta-alanine synthesis|beta-alanine biosynthesis|beta-alanine anabolism													biological_process											owl:Class	
GO:0006446	biolink:NamedThing	regulation of translational initiation	Any process that modulates the frequency, rate or extent of translational initiation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1905622	biolink:NamedThing	negative regulation of leaf development	Any process that stops, prevents or reduces the frequency, rate or extent of leaf development.	tmpzr1t_l9r_go_relaxed.owl	down regulation of leaf development|downregulation of leaf development|down-regulation of leaf development|inhibition of leaf development							pga	2016-10-28T15:29:57Z					biological_process											owl:Class	
GO:0052758	biolink:NamedThing	coenzyme F420-dependent 2,4,6-trinitrophenol reductase activity	Catalysis of the reaction: 2,4,6-trinitrophenol + H- = 2,4,6-trinitrophenol hydride Meisenheimer complex. Coenzyme F420 supplies the hydride (H-) in the reaction.	tmpzr1t_l9r_go_relaxed.owl	TNP reductase activity|coenzyme F420-dependent 2,4,6-trinitrophenol hydride transferase activity				UM-BBD_reactionID:r1065|EC:1.3.99.-			ai	2011-09-28T11:06:03Z					molecular_function											owl:Class	
GO:0019098	biolink:NamedThing	reproductive behavior	The specific behavior of an organism that is associated with reproduction.	tmpzr1t_l9r_go_relaxed.owl	reproductive behaviour|multi-organism reproductive behavior|single-organism reproductive behavior|multicellular organism reproductive behavior|reproductive behavior in a multicellular organism							jl	2012-09-19T16:01:37Z			GO:0033057|GO:0044705|GO:0044704		biological_process											owl:Class	
GO:0060839	biolink:NamedThing	endothelial cell fate commitment	The commitment of a cell to an endothelial cell fate and its capacity to differentiate into an endothelial cell.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-08-11T03:52:53Z					biological_process											owl:Class	
GO:0072148	biolink:NamedThing	epithelial cell fate commitment	The process in which the developmental fate of a cell becomes restricted such that it will develop into an epithelial cell.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-02-24T02:05:03Z					biological_process											owl:Class	
GO:0032494	biolink:NamedThing	response to peptidoglycan	Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptidoglycan stimulus. Peptidoglycan is a bacterial cell wall macromolecule.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0002237	biolink:NamedThing	response to molecule of bacterial origin	Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by molecules of bacterial origin such as peptides derived from bacterial flagellin.	tmpzr1t_l9r_go_relaxed.owl	response to bacteria associated molecule|response to bacterial associated molecule|response to bacterium associated molecule													biological_process											owl:Class	
GO:0051307	biolink:NamedThing	meiotic chromosome separation	The process in which chromosomes are physically detached from each other during meiosis.	tmpzr1t_l9r_go_relaxed.owl	chromosome separation during meiosis|meiotic chromosome resolution													biological_process											owl:Class	
GO:0002711	biolink:NamedThing	positive regulation of T cell mediated immunity	Any process that activates or increases the frequency, rate, or extent of T cell mediated immunity.	tmpzr1t_l9r_go_relaxed.owl	activation of T cell mediated immunity|upregulation of T cell mediated immunity|positive regulation of T-cell mediated immunity|up regulation of T cell mediated immunity|up-regulation of T cell mediated immunity|positive regulation of T-lymphocyte mediated immunity|stimulation of T cell mediated immunity|positive regulation of T lymphocyte mediated immunity													biological_process											owl:Class	
GO:0002708	biolink:NamedThing	positive regulation of lymphocyte mediated immunity	Any process that activates or increases the frequency, rate, or extent of lymphocyte mediated immunity.	tmpzr1t_l9r_go_relaxed.owl	up regulation of lymphocyte mediated immunity|stimulation of lymphocyte mediated immunity|up-regulation of lymphocyte mediated immunity|upregulation of lymphocyte mediated immunity|activation of lymphocyte mediated immunity													biological_process											owl:Class	
GO:0102860	biolink:NamedThing	1-18:1-2-18:2-phosphatidylcholine synthase activity	Catalysis of the reaction: 1-18:1-2-18:1-sn-glycerol-3-phosphocholine + O2 + a reduced electron acceptor <=> 1-18:1-2-18:2-phosphatidylcholine + 2 H2O + an oxidized electron acceptor.	tmpzr1t_l9r_go_relaxed.owl					EC:1.14.19.22|MetaCyc:RXN-8327									molecular_function											owl:Class	
GO:2000441	biolink:NamedThing	negative regulation of toll-like receptor 15 signaling pathway	Any process that stops, prevents or reduces the frequency, rate or extent of toll-like receptor 15 signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of toll-like receptor 15 signalling pathway|negative regulation of TLR15 signaling pathway							bf	2011-03-04T10:29:04Z					biological_process											owl:Class	
GO:0034122	biolink:NamedThing	negative regulation of toll-like receptor signaling pathway	Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of TLR signaling pathway|negative regulation of toll-like receptor signalling pathway													biological_process											owl:Class	
GO:0048477	biolink:NamedThing	oogenesis	The complete process of formation and maturation of an ovum or female gamete from a primordial female germ cell. Examples of this process are found in Mus musculus and Drosophila melanogaster.	tmpzr1t_l9r_go_relaxed.owl	ovum development				Wikipedia:Oogenesis							GO:0009993|GO:0048157		biological_process											owl:Class	
GO:0007281	biolink:NamedThing	germ cell development	The process whose specific outcome is the progression of an immature germ cell over time, from its formation to the mature structure (gamete). A germ cell is any reproductive cell in a multicellular organism.	tmpzr1t_l9r_go_relaxed.owl	primordial germ cell development|germ-cell development													biological_process											owl:Class	
GO:0052089	biolink:NamedThing	modulation by symbiont of host salicylic acid-mediated defense response	Any process in which a symbiont modulates the frequency, rate or extent of the salicylic acid-mediated defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	modulation by organism of salicylic acid-mediated defense response of other organism involved in symbiotic interaction|modulation by organism of host SA-mediated defense response											GO:0052284		biological_process											owl:Class	
GO:0032848	biolink:NamedThing	negative regulation of cellular pH reduction	Any process that stops, prevents, or reduces the frequency, rate, or extent of a process that reduces the internal pH of a cell.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of reduction of pH in cell|down-regulation of cellular pH reduction|negative regulation of cell pH reduction|down regulation of cellular pH reduction|inhibition of cellular pH reduction|downregulation of cellular pH reduction|negative regulation of reduction of cellular pH|negative regulation of intracellular acidification|negative regulation of cellular acidification|negative regulation of intracellular pH reduction													biological_process											owl:Class	
GO:0110038	biolink:NamedThing	negative regulation of nematode male tail tip morphogenesis	Any process that stops, prevents, or reduces the frequency, rate or extent of nematode male tail tip morphogenesis.	tmpzr1t_l9r_go_relaxed.owl								kmv	2017-07-24T20:29:00Z					biological_process											owl:Class	
GO:0071220	biolink:NamedThing	cellular response to bacterial lipoprotein	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bacterial lipoprotein stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-12-03T01:26:36Z					biological_process											owl:Class	
GO:0032493	biolink:NamedThing	response to bacterial lipoprotein	Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bacterial lipoprotein stimulus.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0052148	biolink:NamedThing	modulation by symbiont of host catalytic activity	The process in which an organism effects a change in host enzyme activity. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	modulation of catalytic activity of host by symbiont|regulation by symbiont of host catalytic activity|regulation of catalytic activity of host by symbiont|regulation of host catalytic activity by symbiont|modulation by symbiont of host enzyme activity													biological_process											owl:Class	
GO:0021936	biolink:NamedThing	regulation of cerebellar granule cell precursor proliferation	The process that modulates the frequency, rate or extent of granule cell precursor proliferation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0042406	biolink:NamedThing	extrinsic component of endoplasmic reticulum membrane	The component of the endoplasmic reticulum membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.	tmpzr1t_l9r_go_relaxed.owl	extrinsic to endoplasmic reticulum membrane|extrinsic to ER membrane													cellular_component											owl:Class	
GO:0002607	biolink:NamedThing	regulation of myeloid dendritic cell antigen processing and presentation	Any process that modulates the frequency, rate, or extent of myeloid dendritic cell antigen processing and presentation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0080026	biolink:NamedThing	response to indolebutyric acid	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an indolebutyric acid stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to indolebutyric acid stimulus|response to indole-3-butyric acid stimulus|response to IBA stimulus													biological_process											owl:Class	
GO:0009733	biolink:NamedThing	response to auxin	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an auxin stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to auxin stimulus													biological_process											owl:Class	
GO:1901842	biolink:NamedThing	negative regulation of high voltage-gated calcium channel activity	Any process that stops, prevents or reduces the frequency, rate or extent of high voltage-gated calcium channel activity.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of high voltage gated calcium channel activity|downregulation of high voltage-dependent calcium channel activity|inhibition of high voltage-gated calcium channel activity|inhibition of high voltage-dependent calcium channel activity|inhibition of high voltage gated calcium channel activity|down regulation of high voltage-gated calcium channel activity|downregulation of high voltage gated calcium channel activity|negative regulation of high voltage-dependent calcium channel activity|downregulation of high voltage-gated calcium channel activity|down-regulation of high voltage gated calcium channel activity|down-regulation of high voltage-dependent calcium channel activity|down regulation of high voltage-dependent calcium channel activity|down-regulation of high voltage-gated calcium channel activity|down regulation of high voltage gated calcium channel activity							rl	2013-01-24T19:02:20Z					biological_process											owl:Class	
GO:1901841	biolink:NamedThing	regulation of high voltage-gated calcium channel activity	Any process that modulates the frequency, rate or extent of high voltage-gated calcium channel activity.	tmpzr1t_l9r_go_relaxed.owl	regulation of high voltage gated calcium channel activity|regulation of high voltage-dependent calcium channel activity							rl	2013-01-24T19:02:15Z					biological_process											owl:Class	
GO:1905826	biolink:NamedThing	negative regulation of selenocysteine metabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of selenocysteine metabolic process.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of selenocysteine metabolism|down-regulation of selenocysteine metabolic process|down regulation of selenocysteine metabolism|downregulation of selenocysteine metabolic process|inhibition of selenocysteine metabolism|downregulation of selenocysteine metabolism|down-regulation of selenocysteine metabolism|down regulation of selenocysteine metabolic process|inhibition of selenocysteine metabolic process							sl	2017-01-16T19:01:42Z					biological_process											owl:Class	
GO:1905825	biolink:NamedThing	regulation of selenocysteine metabolic process	Any process that modulates the frequency, rate or extent of selenocysteine metabolic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of selenocysteine metabolism							sl	2017-01-16T19:01:34Z					biological_process											owl:Class	
GO:2000124	biolink:NamedThing	regulation of endocannabinoid signaling pathway	Any process that modulates the frequency, rate or extent of endocannabinoid signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	regulation of endocannabinoid signalling pathway							mah	2010-09-29T09:05:43Z					biological_process											owl:Class	
GO:0008277	biolink:NamedThing	regulation of G protein-coupled receptor signaling pathway	Any process that modulates the frequency, rate or extent of G protein-coupled receptor signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	regulation of G protein coupled receptor protein signalling pathway|regulation of G-protein-coupled receptor protein signalling pathway|regulation of G protein coupled receptor protein signaling pathway|regulation of GPCR protein signalling pathway|regulation of G-protein coupled receptor protein signalling pathway|regulation of GPCR protein signaling pathway|regulation of G-protein coupled receptor protein signaling pathway													biological_process											owl:Class	
GO:0032369	biolink:NamedThing	negative regulation of lipid transport	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	inhibition of lipid transport|down-regulation of lipid transport|downregulation of lipid transport|down regulation of lipid transport													biological_process											owl:Class	
GO:0015995	biolink:NamedThing	chlorophyll biosynthetic process	The chemical reactions and pathways resulting in the formation of chlorophyll, any compound of magnesium complexed in a porphyrin (tetrapyrrole) ring and which functions as a photosynthetic pigment, from less complex precursors.	tmpzr1t_l9r_go_relaxed.owl	chlorophyll synthesis|chlorophyll anabolism|chlorophyll biosynthesis|chlorophyll formation				MetaCyc:CHLOROPHYLL-SYN									biological_process											owl:Class	
GO:1990211	biolink:NamedThing	positive regulation by symbiont of jasmonic acid levels in host	Any process in which an organism activates, maintains or increases the frequency, rate or extent of the jasmonic acid levels in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl								ml	2013-10-09T18:58:37Z					biological_process											owl:Class	
GO:0052024	biolink:NamedThing	positive regulation by symbiont of hormone or growth regulator levels in host	The increase by an organism of the levels of hormones or growth regulators in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	stimulation by symbiont of hormone or growth regulator levels in host|positive modulation of hormone or growth regulator levels in host|upregulation by symbiont of hormone or growth regulator levels in host|activation by symbiont of hormone or growth regulator levels in host|up regulation by symbiont of hormone or growth regulator levels in host|positive regulation by organism of hormone or growth regulator levels in other organism involved in symbiotic interaction|up-regulation by symbiont of hormone or growth regulator levels in host											GO:0052513		biological_process											owl:Class	
GO:0000062	biolink:NamedThing	fatty-acyl-CoA binding	Binding to a fatty-acyl-CoA, any derivative of coenzyme A in which the sulfhydryl group is in thiolester linkage with a fatty acyl group.	tmpzr1t_l9r_go_relaxed.owl	fatty-acyl-coenzyme A binding|fatty-acyl binding	https://github.com/geneontology/go-ontology/issues/19443												molecular_function											owl:Class	
GO:0120227	biolink:NamedThing	acyl-CoA binding	Binding to an acyl-CoA, a thioester that results from the formal condensation of the thiol group of coenzyme A with the carboxy group of any carboxylic acid.	tmpzr1t_l9r_go_relaxed.owl	acyl-coenzyme A binding|acyl binding	https://github.com/geneontology/go-ontology/issues/19243						krc	2020-05-19T16:06:24Z					molecular_function											owl:Class	
GO:1900627	biolink:NamedThing	negative regulation of arugosin biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of arugosin biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	downregulation of arugosin synthesis|inhibition of arugosin biosynthetic process|down regulation of arugosin synthesis|negative regulation of arugosin biosynthesis|down-regulation of arugosin biosynthetic process|down regulation of arugosin formation|down regulation of arugosin biosynthesis|down-regulation of arugosin formation|negative regulation of arugosin anabolism|down-regulation of arugosin synthesis|downregulation of arugosin biosynthetic process|inhibition of arugosin synthesis|negative regulation of arugosin synthesis|inhibition of arugosin biosynthesis|down regulation of arugosin biosynthetic process|inhibition of arugosin formation|downregulation of arugosin anabolism|negative regulation of arugosin formation|down-regulation of arugosin anabolism|down-regulation of arugosin biosynthesis|downregulation of arugosin biosynthesis|down regulation of arugosin anabolism|downregulation of arugosin formation|inhibition of arugosin anabolism							di	2012-05-21T05:48:03Z					biological_process											owl:Class	
GO:0075302	biolink:NamedThing	regulation of basidiospore formation	Any process that modulates the frequency, rate or extent of basidiospore formation, a process in which a sexually produced fungal spore is formed on a basidium in the fungi Basidiomycetes.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0071035	biolink:NamedThing	nuclear polyadenylation-dependent rRNA catabolic process	The chemical reactions and pathways occurring in the nucleus and resulting in the breakdown of a ribosomal RNA (rRNA) molecule, including RNA fragments released as part of processing the primary transcript into multiple mature rRNA species, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target rRNA.	tmpzr1t_l9r_go_relaxed.owl	nuclear poly(A)-dependent rRNA catabolic process							krc	2009-07-29T12:42:39Z					biological_process											owl:Class	
GO:0045976	biolink:NamedThing	negative regulation of mitotic cell cycle, embryonic	Any process that stops, prevents or reduces the rate or extent of progression through the embryonic mitotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl	down regulation of progression through embryonic mitotic cell cycle|negative regulation of progression through embryonic mitotic cell cycle|negative regulation of embryonic mitotic cell cycle|down-regulation of progression through embryonic mitotic cell cycle|negative regulation of embryonic mitotic cell cycle progression|inhibition of progression through embryonic mitotic cell cycle|downregulation of progression through embryonic mitotic cell cycle													biological_process											owl:Class	
GO:0045930	biolink:NamedThing	negative regulation of mitotic cell cycle	Any process that stops, prevents or reduces the rate or extent of progression through the mitotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl	inhibition of progression through mitotic cell cycle|negative regulation of progression through mitotic cell cycle|down regulation of progression through mitotic cell cycle|down-regulation of progression through mitotic cell cycle|downregulation of progression through mitotic cell cycle|negative regulation of mitotic cell cycle progression													biological_process											owl:Class	
GO:1902177	biolink:NamedThing	positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway	Any process that activates or increases the frequency, rate or extent of an oxidative stress-induced intrinsic apoptotic signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	up regulation of intrinsic apoptotic signaling pathway in response to oxidative stress|positive regulation of intrinsic apoptotic signaling pathway in response to oxidative stress|activation of intrinsic apoptotic signaling pathway in response to oxidative stress|upregulation of intrinsic apoptotic signaling pathway in response to oxidative stress|up-regulation of intrinsic apoptotic signaling pathway in response to oxidative stress							pr	2013-05-29T18:30:10Z					biological_process											owl:Class	
GO:1902175	biolink:NamedThing	regulation of oxidative stress-induced intrinsic apoptotic signaling pathway	Any process that modulates the frequency, rate or extent of an oxidative stress-induced intrinsic apoptotic signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	regulation of intrinsic apoptotic signaling pathway in response to oxidative stress							pr	2013-05-29T18:30:00Z					biological_process											owl:Class	
GO:0003192	biolink:NamedThing	mitral valve formation	The developmental process pertaining to the initial formation of the mitral valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-10-08T01:10:19Z					biological_process											owl:Class	
GO:0003190	biolink:NamedThing	atrioventricular valve formation	The developmental process pertaining to the initial formation of the atrioventricular valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable.	tmpzr1t_l9r_go_relaxed.owl	AV valve formation							dph	2009-10-08T01:07:28Z					biological_process											owl:Class	
GO:0062085	biolink:NamedThing	positive regulation of capsule polysaccharide biosynthetic process	Any process that activates, maintains or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of polysaccharides that make up the capsule, a protective structure surrounding some species of bacteria and fungi.	tmpzr1t_l9r_go_relaxed.owl								dph	2018-10-31T16:02:00Z					biological_process											owl:Class	
GO:1904847	biolink:NamedThing	regulation of cell chemotaxis to fibroblast growth factor	Any process that modulates the frequency, rate or extent of cell chemotaxis to fibroblast growth factor.	tmpzr1t_l9r_go_relaxed.owl								rph	2015-12-10T12:04:01Z					biological_process											owl:Class	
GO:0050329	biolink:NamedThing	tetrahydroxypteridine cycloisomerase activity	Catalysis of the reaction: tetrahydroxypteridine = H(+) + xanthine-8-carboxylate.	tmpzr1t_l9r_go_relaxed.owl	tetrahydroxypteridine lyase (isomerizing)				EC:5.5.1.3|RHEA:18097|KEGG_REACTION:R04154|MetaCyc:TETRAHYDROXYPTERIDINE-CYCLOISOMERASE-RXN									molecular_function											owl:Class	
GO:0016872	biolink:NamedThing	intramolecular lyase activity	The catalysis of certain rearrangements of a molecule to break or form a ring.	tmpzr1t_l9r_go_relaxed.owl					EC:5.5.1.-									molecular_function											owl:Class	
GO:0030167	biolink:NamedThing	proteoglycan catabolic process	The chemical reactions and pathways resulting in the breakdown of proteoglycans, any glycoprotein in which the carbohydrate units are glycosaminoglycans.	tmpzr1t_l9r_go_relaxed.owl	proteoglycan breakdown|proteoglycan degradation|proteoglycan catabolism													biological_process											owl:Class	
GO:0006029	biolink:NamedThing	proteoglycan metabolic process	The chemical reactions and pathways involving proteoglycans, any glycoprotein in which the carbohydrate units are glycosaminoglycans.	tmpzr1t_l9r_go_relaxed.owl	proteoglycan metabolism|proteoglycan sulfate transfer													biological_process											owl:Class	
GO:1903946	biolink:NamedThing	negative regulation of ventricular cardiac muscle cell action potential	Any process that stops, prevents or reduces the frequency, rate or extent of ventricular cardiac muscle cell action potential.	tmpzr1t_l9r_go_relaxed.owl	inhibition of ventricular cardiac muscle cell action potential|down-regulation of ventricular cardiac muscle cell action potential|down regulation of ventricular cardiac muscle cell action potential|downregulation of ventricular cardiac muscle cell action potential							nc	2015-02-20T14:31:55Z					biological_process											owl:Class	
GO:0016260	biolink:NamedThing	selenocysteine biosynthetic process	The chemical reactions and pathways resulting in the formation of selenocysteine, an essential component of glutathione peroxidase and some other proteins.	tmpzr1t_l9r_go_relaxed.owl	selenocysteine biosynthesis|selenocysteine formation|selenocysteine synthesis|selenocysteine anabolism													biological_process											owl:Class	
GO:0009070	biolink:NamedThing	serine family amino acid biosynthetic process	The chemical reactions and pathways resulting in the formation of amino acids of the serine family, comprising cysteine, glycine, homoserine, selenocysteine and serine.	tmpzr1t_l9r_go_relaxed.owl	serine family amino acid formation|serine family amino acid anabolism|serine family amino acid biosynthesis|serine family amino acid synthesis													biological_process											owl:Class	
GO:0034264	biolink:NamedThing	isopentenyl adenine metabolic process	The chemical reactions and pathways involving the cytokinin 6-isopentenyladenine.	tmpzr1t_l9r_go_relaxed.owl	isopentenyl adenine metabolism|isopentenyladenine metabolic process													biological_process											owl:Class	
GO:0009690	biolink:NamedThing	cytokinin metabolic process	The chemical reactions and pathways involving cytokinins, a class of adenine-derived compounds that can function in plants as growth regulators.	tmpzr1t_l9r_go_relaxed.owl	cytokinin metabolism													biological_process											owl:Class	
GO:0070959	biolink:NamedThing	negative regulation of neutrophil mediated killing of fungus	Any process that decreases the frequency, rate or extent of the directed killing of a fungal cell by a neutrophil.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of neutrophil mediated killing of fungus|downregulation of neutrophil mediated killing of fungus|down regulation of neutrophil mediated killing of fungus|inhibition of neutrophil mediated killing of fungus							mah	2009-10-01T02:20:17Z					biological_process											owl:Class	
GO:1900324	biolink:NamedThing	regulation of maltotriulose transport	Any process that modulates the frequency, rate or extent of maltotriulose transport.	tmpzr1t_l9r_go_relaxed.owl								tt	2012-04-06T01:48:06Z					biological_process											owl:Class	
GO:0061684	biolink:NamedThing	chaperone-mediated autophagy	The autophagy process which begins when chaperones and co-chaperones recognize a target motif and unfold the substrate protein. The proteins are then transported to the lysosome where they are degraded.	tmpzr1t_l9r_go_relaxed.owl	CMA|chaperone-assisted selective autophagy|CASA	https://github.com/geneontology/go-ontology/issues/20850			Wikipedia:Chaperone-mediated_autophagy			dph	2015-03-04T14:35:26Z					biological_process											owl:Class	
GO:0030163	biolink:NamedThing	protein catabolic process	The chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds.	tmpzr1t_l9r_go_relaxed.owl	protein degradation|protein catabolism|multicellular organismal protein catabolic process|pheromone catabolic process|pheromone catabolism|protein breakdown				Wikipedia:Protein_catabolism	This term refers to the breakdown of mature proteins. For cleavage events involved in generating a mature protein from a precursor, consider instead the term 'protein maturation ; GO:0051604' and its children.						GO:0044254		biological_process											owl:Class	
GO:1903431	biolink:NamedThing	positive regulation of cell maturation	Any process that activates or increases the frequency, rate or extent of cell maturation.	tmpzr1t_l9r_go_relaxed.owl	activation of functional differentiation|up-regulation of functional differentiation|upregulation of functional differentiation|upregulation of cell maturation|activation of cell maturation|positive regulation of functional differentiation|up regulation of functional differentiation|up-regulation of cell maturation|up regulation of cell maturation							jl	2014-09-15T13:31:41Z					biological_process											owl:Class	
GO:1905176	biolink:NamedThing	positive regulation of vascular associated smooth muscle cell dedifferentiation	Any process that activates or increases the frequency, rate or extent of vascular smooth muscle cell dedifferentiation.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of vascular smooth muscle cell dedifferentiation|upregulation of vascular smooth muscle cell dedifferentiation|up regulation of vascular smooth muscle cell dedifferentiation|activation of vascular smooth muscle cell dedifferentiation|positive regulation of vascular smooth muscle cell dedifferentiation							rph	2016-05-03T12:32:13Z					biological_process											owl:Class	
GO:1905174	biolink:NamedThing	regulation of vascular associated smooth muscle cell dedifferentiation	Any process that modulates the frequency, rate or extent of vascular smooth muscle cell dedifferentiation.	tmpzr1t_l9r_go_relaxed.owl	regulation of vascular smooth muscle cell dedifferentiation							rph	2016-05-03T12:31:57Z					biological_process											owl:Class	
GO:0061135	biolink:NamedThing	endopeptidase regulator activity	Binds to and modulates the activity of a peptidase, any enzyme that hydrolyzes nonterminal peptide bonds in polypeptides.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-05-17T01:19:36Z					molecular_function											owl:Class	
GO:1905808	biolink:NamedThing	positive regulation of synapse pruning	Any process that activates or increases the frequency, rate or extent of synapse pruning.	tmpzr1t_l9r_go_relaxed.owl	regulation of synapse removal|regulation of synapse clearance|regulation of synapse elimination|upregulation of synapse disassembly|up-regulation of synapse disassembly|activation of synapse disassembly|regulation of synapse disassembly|up regulation of synapse disassembly							tb	2017-01-11T22:03:33Z					biological_process											owl:Class	
GO:0071675	biolink:NamedThing	regulation of mononuclear cell migration	Any process that modulates the rate, frequency or extent of mononuclear cell migration. Mononuclear cell migration is the movement of a mononuclear cell within or between different tissues and organs of the body.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-02-16T02:11:53Z					biological_process											owl:Class	
GO:0021507	biolink:NamedThing	posterior neuropore closure	The joining together of the neural folds of the caudal opening of the neural tube. The posterior neuropore appears before the process of neural tube closure is complete.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0016331	biolink:NamedThing	morphogenesis of embryonic epithelium	The process in which the anatomical structures of embryonic epithelia are generated and organized.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0016269	biolink:NamedThing	O-glycan processing, core 3	The stepwise addition of carbohydrate or carbohydrate derivative residues to the initially added O-linked residue (usually GalNAc) to form the core 3 O-glycan structure, GlcNAc-beta-(1->3)-GalNAc.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0016266	biolink:NamedThing	O-glycan processing	The stepwise addition of carbohydrate or carbohydrate derivative residues to the initially added O-linked residue (usually GalNAc) to form a core O-glycan structure.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0140446	biolink:NamedThing	fumigermin biosynthetic process	The chemical reactions and pathways resulting in the formation of fumigermin, an alpha-pyrone secondary metabolite found in some species of fungi such as Aspergillus fumigatus.	tmpzr1t_l9r_go_relaxed.owl	fumigermin formation|fumigermin anabolism|fumigermin synthesis|fumigermin biosynthesis							pg	2020-03-31T12:02:29Z					biological_process											owl:Class	
GO:1904833	biolink:NamedThing	positive regulation of removal of superoxide radicals	Any process that activates or increases the frequency, rate or extent of removal of superoxide radicals.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of removal of oxygen free radicals|up regulation of removal of superoxide radicals|up-regulation of removal of O2-|positive regulation of cellular detoxification of superoxide radicals|activation of removal of superoxide radicals|upregulation of cellular detoxification of superoxide radicals|positive regulation of removal of O2-|upregulation of removal of O2-|activation of removal of O2-|upregulation of removal of superoxide radicals|upregulation of removal of oxygen free radicals|up regulation of cellular detoxification of superoxide radicals|positive regulation of removal of oxygen free radicals|activation of cellular detoxification of superoxide radicals|activation of removal of oxygen free radicals|up-regulation of removal of superoxide radicals|up regulation of removal of oxygen free radicals|up-regulation of cellular detoxification of superoxide radicals|up regulation of removal of O2-							rph	2015-11-24T15:30:26Z					biological_process											owl:Class	
GO:2000121	biolink:NamedThing	regulation of removal of superoxide radicals	Any process that modulates the frequency, rate or extent of removal of superoxide radicals.	tmpzr1t_l9r_go_relaxed.owl	regulation of removal of O2-|regulation of removal of oxygen free radicals							dhl	2010-09-27T05:30:37Z					biological_process											owl:Class	
GO:0071072	biolink:NamedThing	negative regulation of phospholipid biosynthetic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of phospholipids.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of phospholipid anabolism|downregulation of phospholipid biosynthetic process|negative regulation of phospholipid formation|negative regulation of phospholipid synthesis|down regulation of phospholipid biosynthetic process|negative regulation of phospholipid biosynthesis|inhibition of phospholipid biosynthetic process|down-regulation of phospholipid biosynthetic process							mah	2009-11-04T03:14:08Z					biological_process											owl:Class	
GO:1901018	biolink:NamedThing	positive regulation of potassium ion transmembrane transporter activity	Any process that activates or increases the frequency, rate or extent of potassium ion transmembrane transporter activity.	tmpzr1t_l9r_go_relaxed.owl	upregulation of potassium ion transmembrane transporter activity|up-regulation of potassium transporter activity|up regulation of potassium transporter activity|upregulation of potassium transporter activity|activation of potassium transporter activity|activation of potassium ion transmembrane transporter activity|up regulation of potassium ion transmembrane transporter activity|up-regulation of potassium ion transmembrane transporter activity|positive regulation of potassium transporter activity							rl	2012-06-15T01:14:18Z					biological_process											owl:Class	
GO:1901733	biolink:NamedThing	quercetin catabolic process	The chemical reactions and pathways resulting in the breakdown of quercetin.	tmpzr1t_l9r_go_relaxed.owl	quercetin degradation|quercetin catabolism|quercetin breakdown							yaf	2013-01-11T10:25:15Z					biological_process											owl:Class	
GO:1901732	biolink:NamedThing	quercetin metabolic process	The chemical reactions and pathways involving quercetin.	tmpzr1t_l9r_go_relaxed.owl	quercetin metabolism							yaf	2013-01-11T10:25:11Z					biological_process											owl:Class	
GO:0031453	biolink:NamedThing	positive regulation of heterochromatin assembly	Any process that activates or increases the frequency, rate or extent of heterochromatin formation.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of heterochromatin formation|stimulation of heterochromatin formation|activation of heterochromatin formation|up-regulation of heterochromatin formation|up regulation of heterochromatin formation|upregulation of heterochromatin formation													biological_process											owl:Class	
GO:0006883	biolink:NamedThing	cellular sodium ion homeostasis	Any process involved in the maintenance of an internal steady state of sodium ions at the level of a cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0030004	biolink:NamedThing	cellular monovalent inorganic cation homeostasis	Any process involved in the maintenance of an internal steady state of monovalent inorganic cations at the level of a cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0032958	biolink:NamedThing	inositol phosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of an inositol phosphate, 1,2,3,4,5,6-cyclohexanehexol, with one or more phosphate groups attached.	tmpzr1t_l9r_go_relaxed.owl	myo-inositol phosphate biosynthetic process|inositol phosphate formation|inositol phosphate anabolism|inositol phosphate biosynthesis|inositol phosphate synthesis													biological_process											owl:Class	
GO:0046173	biolink:NamedThing	polyol biosynthetic process	The chemical reactions and pathways resulting in the formation of a polyol, any alcohol containing three or more hydroxyl groups attached to saturated carbon atoms.	tmpzr1t_l9r_go_relaxed.owl	polyol synthesis|polyhydric alcohol biosynthetic process|polyol formation|polyol biosynthesis|polyol anabolism													biological_process											owl:Class	
GO:0033370	biolink:NamedThing	maintenance of protein location in mast cell secretory granule	A process in which a protein is maintained in a secretory granule in a mast cell and prevented from moving elsewhere.	tmpzr1t_l9r_go_relaxed.owl	maintenance of protein localization in mast cell secretory granule|mast cell protein retention													biological_process											owl:Class	
GO:2000077	biolink:NamedThing	negative regulation of type B pancreatic cell development	Any process that stops, prevents, or reduces the frequency, rate or extent of pancreatic B cell development.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of pancreatic B cell development|negative regulation of pancreatic beta cell development							tb	2010-08-27T11:21:17Z					biological_process											owl:Class	
GO:0010721	biolink:NamedThing	negative regulation of cell development	Any process that decreases the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0035495	biolink:NamedThing	regulation of SNARE complex disassembly	Any process that modulates the frequency, rate or extent of disassembly of the SNARE complex. The SNARE complex is a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers.	tmpzr1t_l9r_go_relaxed.owl								bf	2010-04-26T02:56:53Z					biological_process											owl:Class	
GO:0010213	biolink:NamedThing	non-photoreactive DNA repair	A DNA repair process that is involved in repairing UV-induced DNA damage under non-photoreactivating conditions. The mechanism by which this repair process operates has not yet been completely elucidated.	tmpzr1t_l9r_go_relaxed.owl	light-independent DNA repair													biological_process											owl:Class	
GO:0006281	biolink:NamedThing	DNA repair	The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:DNA_repair									biological_process											owl:Class	
GO:0031527	biolink:NamedThing	filopodium membrane	The portion of the plasma membrane surrounding a filopodium.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0045920	biolink:NamedThing	negative regulation of exocytosis	Any process that stops, prevents, or reduces the frequency, rate or extent of exocytosis.	tmpzr1t_l9r_go_relaxed.owl	downregulation of exocytosis|down-regulation of exocytosis|inhibition of exocytosis|down regulation of exocytosis													biological_process											owl:Class	
GO:0017157	biolink:NamedThing	regulation of exocytosis	Any process that modulates the frequency, rate or extent of exocytosis.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1902338	biolink:NamedThing	negative regulation of apoptotic process involved in morphogenesis	Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic process involved in morphogenesis.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of morphogenetic apoptosis|down regulation of morphogenetic apoptosis|down-regulation of apoptosis involved in development|downregulation of apoptotic process involved in morphogenesis|inhibition of morphogenetic apoptosis|negative regulation of apoptosis involved in morphogenesis|negative regulation of morphogenetic apoptosis|negative regulation of apoptosis involved in development|inhibition of apoptosis involved in morphogenesis|inhibition of apoptotic process involved in morphogenesis|inhibition of apoptosis involved in development|downregulation of morphogenetic apoptosis|down regulation of apoptosis involved in morphogenesis|downregulation of apoptosis involved in morphogenesis|down regulation of apoptosis involved in development|downregulation of apoptosis involved in development|down-regulation of apoptotic process involved in morphogenesis|down regulation of apoptotic process involved in morphogenesis|down-regulation of apoptosis involved in morphogenesis							sart	2013-07-29T15:03:25Z					biological_process											owl:Class	
GO:1902337	biolink:NamedThing	regulation of apoptotic process involved in morphogenesis	Any process that modulates the frequency, rate or extent of apoptotic process involved in morphogenesis.	tmpzr1t_l9r_go_relaxed.owl	regulation of morphogenetic apoptosis|regulation of apoptosis involved in development|regulation of apoptosis involved in morphogenesis							sart	2013-07-29T15:03:16Z					biological_process											owl:Class	
GO:1904815	biolink:NamedThing	negative regulation of protein localization to chromosome, telomeric region	Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to chromosome, telomeric region.	tmpzr1t_l9r_go_relaxed.owl	down regulation of protein localisation to chromosome, telomeric region|down regulation of protein localization to chromosome, telomeric region|down-regulation of protein localisation to chromosome, telomeric region|down-regulation of protein localization to chromosome, telomeric region|inhibition of protein localisation to chromosome, telomeric region|downregulation of protein localization to chromosome, telomeric region|down-regulation of protein localization to telomere|negative regulation of protein localisation to chromosome, telomeric region|downregulation of protein localisation to chromosome, telomeric region|down regulation of protein localization to telomere|inhibition of protein localization to chromosome, telomeric region|inhibition of protein localization to telomere|downregulation of protein localization to telomere|negative regulation of protein localization to telomere							nc	2015-11-16T12:18:51Z					biological_process											owl:Class	
GO:1900993	biolink:NamedThing	(-)-secologanin catabolic process	The chemical reactions and pathways resulting in the breakdown of (-)-secologanin.	tmpzr1t_l9r_go_relaxed.owl	(-)-secologanin degradation|(-)-secologanin breakdown|(-)-secologanin catabolism							yaf	2012-06-14T09:51:39Z					biological_process											owl:Class	
GO:0046176	biolink:NamedThing	aldonic acid catabolic process	The chemical reactions and pathways resulting in the breakdown of aldonic acid, a monocarboxylic acid with a chain of three or more carbon atoms, derived from an aldose by oxidation of the aldehydic group.	tmpzr1t_l9r_go_relaxed.owl	aldonic acid degradation|aldonic acid catabolism|aldonic acid breakdown													biological_process											owl:Class	
GO:2001242	biolink:NamedThing	regulation of intrinsic apoptotic signaling pathway	Any process that modulates the frequency, rate or extent of intrinsic apoptotic signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	regulation of intrinsic apoptotic signalling pathway|regulation of intrinsic apoptosis|regulation of intrinsic apoptotic pathway|regulation of mitochondrial-mediated apoptotic pathway							pr	2011-11-24T01:35:56Z					biological_process											owl:Class	
GO:0052686	biolink:NamedThing	perillic acid-CoA ligase (AMP-forming) activity	Catalysis of the reaction: perillic acid + CoA-SH + ATP = H2O + AMP + diphosphate + perillyl-CoA.	tmpzr1t_l9r_go_relaxed.owl	perillyl-CoA synthetase activity|perillic acid:CoA ligase (AMP-forming) activity				KEGG_REACTION:R06368									molecular_function											owl:Class	
GO:0016405	biolink:NamedThing	CoA-ligase activity	Catalysis of the reaction: substrate + ATP + CoASH = AMP + diphosphate + substrate-CoA.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-159567|Reactome:R-HSA-159443|Reactome:R-HSA-177157|Reactome:R-HSA-6798345									molecular_function											owl:Class	
GO:0070895	biolink:NamedThing	negative regulation of transposon integration	Any process that stops, prevents, or reduces the frequency, rate or extent of transposon integration, a process in which a transposable element is incorporated into another DNA molecule.	tmpzr1t_l9r_go_relaxed.owl	inhibition of transposon integration|down regulation of transposon integration|down-regulation of transposon integration|downregulation of transposon integration							mah	2009-09-01T04:20:36Z					biological_process											owl:Class	
GO:0070894	biolink:NamedThing	regulation of transposon integration	Any process that modulates the frequency, rate or extent of regulation of transposon integration, a process in which a transposable element is incorporated into another DNA molecule.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-09-01T04:14:09Z					biological_process											owl:Class	
GO:0071594	biolink:NamedThing	thymocyte aggregation	The adhesion of one thymocyte (an immature T cell) to one or more other thymocytes via adhesion molecules.	tmpzr1t_l9r_go_relaxed.owl	immature T-lymphocyte aggregation|thymic lymphocyte aggregation|immature T cell aggregation|T cell precursor aggregation|immature T-cell aggregation							mah	2010-01-29T01:38:49Z					biological_process											owl:Class	
GO:0072526	biolink:NamedThing	pyridine-containing compound catabolic process	The chemical reactions and pathways resulting in the breakdown of a pyridine-containing compound, i.e. any compound that contains pyridine or a formal derivative thereof.	tmpzr1t_l9r_go_relaxed.owl	pyridine and derivative catabolic process|pyridine-containing compound degradation|pyridine-containing compound breakdown|pyridine-containing compound catabolism							mah	2011-01-04T03:23:14Z					biological_process											owl:Class	
GO:0044270	biolink:NamedThing	cellular nitrogen compound catabolic process	The chemical reactions and pathways resulting in the breakdown of organic and inorganic nitrogenous compounds.	tmpzr1t_l9r_go_relaxed.owl	nitrogen compound breakdown|nitrogen compound catabolism|nitrogen compound degradation													biological_process											owl:Class	
GO:0006876	biolink:NamedThing	cellular cadmium ion homeostasis	Any process involved in the maintenance of an internal steady state of cadmium ions at the level of a cell.	tmpzr1t_l9r_go_relaxed.owl	cadmium homeostasis													biological_process											owl:Class	
GO:0055073	biolink:NamedThing	cadmium ion homeostasis	Any process involved in the maintenance of an internal steady state of cadmium ions within an organism or cell.	tmpzr1t_l9r_go_relaxed.owl	cadmium homeostasis													biological_process											owl:Class	
GO:0061014	biolink:NamedThing	positive regulation of mRNA catabolic process	Any process that increases the rate, frequency, or extent of a mRNA catabolic process, the chemical reactions and pathways resulting in the breakdown of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of mRNA decay							dph	2010-01-29T01:58:03Z					biological_process											owl:Class	
GO:0071301	biolink:NamedThing	cellular response to vitamin B1	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin B1 stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to thiamin|cellular response to thiamine							mah	2009-12-10T04:32:09Z					biological_process											owl:Class	
GO:0010266	biolink:NamedThing	response to vitamin B1	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin B1 stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to thiamine|response to thiamin													biological_process											owl:Class	
GO:0003691	biolink:NamedThing	double-stranded telomeric DNA binding	Binding to double-stranded telomere-associated DNA.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0003690	biolink:NamedThing	double-stranded DNA binding	Binding to double-stranded DNA.	tmpzr1t_l9r_go_relaxed.owl	dsDNA binding													molecular_function											owl:Class	
GO:0061297	biolink:NamedThing	positive regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis	Any process that increases the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the mesonephros.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of mesenchymal stem cell apoptosis involved in mesonephric nephron morphogenesis|positive regulation of mesenchymal stem cell apoptotic process involved in mesonephric nephron morphogenesis							dph	2010-09-06T09:58:59Z					biological_process											owl:Class	
GO:0061295	biolink:NamedThing	regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis	Any process that modulates the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the mesonephros.	tmpzr1t_l9r_go_relaxed.owl	regulation of mesenchymal stem cell apoptosis involved in mesonephric nephron morphogenesis|regulation of mesenchymal stem cell apoptotic process involved in mesonephric nephron morphogenesis							dph	2010-09-06T09:48:56Z					biological_process											owl:Class	
GO:1903632	biolink:NamedThing	positive regulation of aminoacyl-tRNA ligase activity	Any process that activates or increases the frequency, rate or extent of aminoacyl-tRNA ligase activity.	tmpzr1t_l9r_go_relaxed.owl	upregulation of aminoacyl-tRNA synthetase auxiliary protein activity|up regulation of aminoacyl-tRNA synthetase activity|activation of aminoacyl-tRNA ligase activity|up regulation of aminoacyl-tRNA synthetase auxiliary protein activity|positive regulation of aminoacyl-tRNA synthetase activity|upregulation of aminoacyl-tRNA ligase activity|upregulation of aminoacyl-tRNA synthetase activity|up-regulation of aminoacyl-tRNA synthetase activity|activation of aminoacyl-tRNA synthetase activity|positive regulation of aminoacyl-tRNA synthetase auxiliary protein activity|activation of aminoacyl-tRNA synthetase auxiliary protein activity|up-regulation of aminoacyl-tRNA ligase activity|up regulation of aminoacyl-tRNA ligase activity|up-regulation of aminoacyl-tRNA synthetase auxiliary protein activity							sl	2014-11-20T00:22:20Z					biological_process											owl:Class	
GO:0035497	biolink:NamedThing	cAMP response element binding	Binding to a cyclic AMP response element (CRE), a short palindrome-containing sequence found in the promoters of genes whose expression is regulated in response to cyclic AMP.	tmpzr1t_l9r_go_relaxed.owl	cyclic-AMP response element binding|cyclic AMP response element binding|CRE binding|cAMP-responsive element binding|cyclic-AMP-responsive element binding					Note that as agreed during the transcription overhaul, terms specifying binding to specific transcription regulatory motifs are no longer being created. The level of specificity GO has decided to go to is the "core promoter", "core promoter proximal region" and "enhancer". To capture more detail, please consider using column 16.		bf	2010-04-29T09:26:47Z					molecular_function											owl:Class	
GO:0047999	biolink:NamedThing	hyponitrite reductase activity	Catalysis of the reaction: 2 hydroxylamine + 2 NAD(+) = 2 H(+) + hyponitrous acid + 2 NADH.	tmpzr1t_l9r_go_relaxed.owl	NADH:hyponitrite oxidoreductase activity|hydroxylamine:NAD+ oxidoreductase activity|NADH2:hyponitrite oxidoreductase activity				EC:1.7.1.5|RHEA:19337|MetaCyc:HYPONITRITE-REDUCTASE-RXN|KEGG_REACTION:R00023									molecular_function											owl:Class	
GO:0046857	biolink:NamedThing	oxidoreductase activity, acting on other nitrogenous compounds as donors, with NAD or NADP as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which a nitrogenous group, excluding NH and NH2 groups, acts as a hydrogen or electron donor and reduces NAD or NADP.	tmpzr1t_l9r_go_relaxed.owl					EC:1.7.1.-									molecular_function											owl:Class	
GO:1900140	biolink:NamedThing	regulation of seedling development	Any process that modulates the frequency, rate or extent of seedling development.	tmpzr1t_l9r_go_relaxed.owl								dhl	2012-03-01T09:26:07Z					biological_process											owl:Class	
GO:0048580	biolink:NamedThing	regulation of post-embryonic development	Any process that modulates the frequency, rate or extent of post-embryonic development. Post-embryonic development is defined as the process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0000097	biolink:NamedThing	sulfur amino acid biosynthetic process	The chemical reactions and pathways resulting in the formation of amino acids containing sulfur, comprising cysteine, methionine and selenocysteine.	tmpzr1t_l9r_go_relaxed.owl	sulfur amino acid anabolism|sulphur amino acid biosynthesis|sulphur amino acid biosynthetic process|sulfur amino acid synthesis|sulfur amino acid biosynthesis|sulfur amino acid formation													biological_process											owl:Class	
GO:0046514	biolink:NamedThing	ceramide catabolic process	The chemical reactions and pathways resulting in the breakdown of ceramides, any N-acetylated sphingoid.	tmpzr1t_l9r_go_relaxed.owl	ceramide degradation|ceramide breakdown|ceramide catabolism													biological_process											owl:Class	
GO:0061209	biolink:NamedThing	cell proliferation involved in mesonephros development	The multiplication or reproduction of cells, resulting in the expansion of the population in the mesonephros.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-08-17T03:22:46Z					biological_process											owl:Class	
GO:0006978	biolink:NamedThing	DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator	A cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, resulting in the induction of the transcription of p21 (also known as WAF1, CIP1 and SDI1) or any equivalent protein, in response to the detection of DNA damage.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0042772	biolink:NamedThing	DNA damage response, signal transduction resulting in transcription	A cascade of processes initiated in response to the detection of DNA damage, and resulting in the induction of transcription.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0019211	biolink:NamedThing	phosphatase activator activity	Binds to and increases the activity of a phosphatase, an enzyme which catalyzes of the removal of a phosphate group from a substrate molecule.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0051481	biolink:NamedThing	negative regulation of cytosolic calcium ion concentration	Any process that decreases the concentration of calcium ions in the cytosol.	tmpzr1t_l9r_go_relaxed.owl	cytoplasmic calcium ion concentration reduction|reduction of cytoplasmic calcium ion concentration|reduction of calcium ion concentration in cytosol|reduction of cytosolic calcium ion concentration|cytosolic calcium ion concentration reduction|reduction of calcium ion concentration in cytoplasm													biological_process											owl:Class	
GO:0051480	biolink:NamedThing	regulation of cytosolic calcium ion concentration	Any process involved in the maintenance of an internal steady state of calcium ions within the cytosol of a cell or between the cytosol and its surroundings.	tmpzr1t_l9r_go_relaxed.owl	regulation of calcium ion concentration in cytoplasm|cytoplasmic calcium ion homeostasis|calcium ion homeostasis in cytoplasm|regulation of calcium ion concentration in cytosol|regulation of cytoplasmic calcium ion concentration|cytosolic calcium ion concentration regulation|cytoplasmic calcium ion concentration regulation|calcium ion homeostasis in cytosol													biological_process											owl:Class	
GO:1900843	biolink:NamedThing	regulation of monodictyphenone biosynthetic process	Any process that modulates the frequency, rate or extent of monodictyphenone biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of monodictyphenone synthesis|regulation of monodictyphenone biosynthesis|regulation of monodictyphenone anabolism|regulation of monodictyphenone formation							di	2012-06-07T09:40:38Z					biological_process											owl:Class	
GO:0034859	biolink:NamedThing	benzothiazole monooxygenase activity	Catalysis of the reaction: benzothiazole + 1/2 O2 = 2-hydroxybenzothiazole.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r1292									molecular_function											owl:Class	
GO:2000968	biolink:NamedThing	positive regulation of cell wall polysaccharide catabolic process	Any process that activates or increases the frequency, rate or extent of cell wall polysaccharide catabolic process.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of cell wall polysaccharide breakdown							tt	2011-08-01T02:30:37Z					biological_process											owl:Class	
GO:0009164	biolink:NamedThing	nucleoside catabolic process	The chemical reactions and pathways resulting in the breakdown of any one of a family of organic molecules consisting of a purine or pyrimidine base covalently bonded to a sugar ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside).	tmpzr1t_l9r_go_relaxed.owl	nucleoside degradation|nucleoside breakdown|nucleoside catabolism													biological_process											owl:Class	
GO:1901554	biolink:NamedThing	response to paracetamol	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a paracetamol stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to acetaminophen							hp	2012-11-02T09:43:23Z					biological_process											owl:Class	
GO:2000632	biolink:NamedThing	negative regulation of pre-miRNA processing	Any process that stops, prevents or reduces the frequency, rate or extent of pre-microRNA processing.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of pre-microRNA processing							dph	2011-04-18T03:50:19Z					biological_process											owl:Class	
GO:1905845	biolink:NamedThing	positive regulation of cellular response to gamma radiation	Any process that activates or increases the frequency, rate or extent of cellular response to gamma radiation.	tmpzr1t_l9r_go_relaxed.owl	upregulation of cellular response to gamma ray|activation of cellular response to gamma ray|activation of cellular response to gamma-ray photon|upregulation of cellular response to gamma radiation|up regulation of cellular response to gamma radiation|upregulation of cellular response to gamma-ray photon|up-regulation of cellular response to gamma ray|activation of cellular response to gamma radiation|up-regulation of cellular response to gamma radiation|up-regulation of cellular response to gamma-ray photon|positive regulation of cellular response to gamma-ray photon|up regulation of cellular response to gamma ray|up regulation of cellular response to gamma-ray photon|positive regulation of cellular response to gamma ray							rz	2017-01-19T10:24:57Z					biological_process											owl:Class	
GO:0106385	biolink:NamedThing	dIMP salvage	Any process which produces a dIMP from derivatives of it, without de novo synthesis.	tmpzr1t_l9r_go_relaxed.owl								hjd	2021-06-11T20:03:19Z					biological_process											owl:Class	
GO:0009171	biolink:NamedThing	purine deoxyribonucleoside monophosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of purine deoxyribonucleoside monophosphate, a compound consisting of a purine base linked to a deoxyribose sugar esterified with phosphate on the sugar.	tmpzr1t_l9r_go_relaxed.owl	purine deoxyribonucleoside monophosphate anabolism|purine deoxyribonucleoside monophosphate synthesis|purine deoxyribonucleoside monophosphate biosynthesis|purine deoxyribonucleoside monophosphate formation													biological_process											owl:Class	
GO:0008995	biolink:NamedThing	ribonuclease E activity	Catalysis of the cleavage of single-stranded RNA that is monophosphorylated at its 5'-end; cleavage occurs predominantly at 5 nucleotides from the 5'-end and in A + U-rich regions, and is blocked by the presence of a 5'-triphosphate group.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:3.1.26.12-RXN									molecular_function											owl:Class	
GO:0004540	biolink:NamedThing	ribonuclease activity	Catalysis of the hydrolysis of phosphodiester bonds in chains of RNA.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0009246	biolink:NamedThing	enterobacterial common antigen biosynthetic process	The chemical reactions and pathways resulting in the formation of the enterobacterial common antigen, an acidic polysaccharide containing N-acetyl-D-glucosamine, N-acetyl-D-mannosaminouronic acid, and 4-acetamido-4,6-dideoxy-D-galactose. A major component of the cell wall outer membrane of Gram-negative bacteria.	tmpzr1t_l9r_go_relaxed.owl	enterobacterial common antigen biosynthesis|enterobacterial common antigen anabolism|enterobacterial common antigen formation|enterobacterial common antigen synthesis				MetaCyc:ECASYN-PWY									biological_process											owl:Class	
GO:0070598	biolink:NamedThing	cell wall (1->3)-alpha-glucan biosynthetic process	The chemical reactions and pathways resulting in the formation of (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-glucosidic bonds, found in the walls of cells.	tmpzr1t_l9r_go_relaxed.owl	cell wall 1,3-alpha-glucan anabolism|cell wall alpha-1,3-glucan formation|cell wall alpha-1,3-glucan anabolism|cell wall 1,3-alpha-glucan biosynthetic process|cell wall 1,3-alpha-glucan synthesis|cell wall alpha-1,3-glucan biosynthetic process|cell wall 1,3-alpha-glucan formation|cell wall 1,3-alpha-glucan biosynthesis|cell wall alpha-1,3-glucan synthesis|cell wall alpha-1,3-glucan biosynthesis							mah	2009-04-28T04:04:59Z					biological_process											owl:Class	
GO:0070592	biolink:NamedThing	cell wall polysaccharide biosynthetic process	The chemical reactions and pathways resulting in the formation of a polysaccharide destined to form part of a cell wall.	tmpzr1t_l9r_go_relaxed.owl	cell wall polysaccharide synthesis|cell wall polysaccharide biosynthesis|cell wall polysaccharide anabolism							mah	2009-04-28T01:25:54Z					biological_process											owl:Class	
GO:0070607	biolink:NamedThing	regulation of cell wall (1->3)-alpha-glucan metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds, found in the walls of cells.	tmpzr1t_l9r_go_relaxed.owl	regulation of cell wall 1,3-alpha-glucan metabolic process|regulation of cell wall 1,3-alpha-glucan metabolism|regulation of cell wall alpha-1,3 glucan metabolic process|regulation of cell wall alpha-1,3 glucan metabolism							mah	2009-04-29T01:24:57Z					biological_process											owl:Class	
GO:0060462	biolink:NamedThing	lung lobe development	The biological process whose specific outcome is the progression of a lung lobe from an initial condition to its mature state. This process begins with the formation of a lung lobe by branching morphogenesis and ends with the mature structure. A lung lobe is one of the rounded projections that compose the lung.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0021982	biolink:NamedThing	pineal gland development	The progression of the pineal gland over time from its initial formation until its mature state. The pineal gland is an endocrine gland that secretes melatonin and is involved in circadian rhythms.	tmpzr1t_l9r_go_relaxed.owl	epiphysis development													biological_process											owl:Class	
GO:0048732	biolink:NamedThing	gland development	The process whose specific outcome is the progression of a gland over time, from its formation to the mature structure. A gland is an organ specialised for secretion.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0005141	biolink:NamedThing	interleukin-10 receptor binding	Binding to an interleukin-10 receptor.	tmpzr1t_l9r_go_relaxed.owl	interleukin-10 receptor ligand|IL-10													molecular_function											owl:Class	
GO:0030858	biolink:NamedThing	positive regulation of epithelial cell differentiation	Any process that activates or increases the frequency, rate or extent of epithelial cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	upregulation of epithelial cell differentiation|activation of epithelial cell differentiation|up regulation of epithelial cell differentiation|stimulation of epithelial cell differentiation|up-regulation of epithelial cell differentiation													biological_process											owl:Class	
GO:0030856	biolink:NamedThing	regulation of epithelial cell differentiation	Any process that modulates the frequency, rate or extent of epithelial cell differentiation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0071515	biolink:NamedThing	genetic imprinting at mating-type locus	A genetic imprinting process in which a stable single-strand DNA lesion triggers programmed gene conversion at the mating-type locus, thereby restricting mating-type interconversion to one of the two sister chromatids during DNA replication.	tmpzr1t_l9r_go_relaxed.owl	mating type determination, imprinting							mah	2010-01-06T12:58:56Z					biological_process											owl:Class	
GO:1990973	biolink:NamedThing	transmembrane actin-associated (TAN) line	A linear array of nuclear envelope membrane proteins composed of nesprin-2G and SUN2, which couple the nucleus to moving actin cables, resulting in rearward nuclear transport (away from the leading edge).	tmpzr1t_l9r_go_relaxed.owl	TAN line							hjd	2016-06-22T15:05:09Z					cellular_component											owl:Class	
GO:0071274	biolink:NamedThing	isoquinoline alkaloid catabolic process	The chemical reactions and pathways resulting in the breakdown of isoquinoline alkaloids, alkaloid compounds that contain bicyclic N-containing aromatic rings and are derived from a 3,4-dihydroxytyramine (dopamine) precursor that undergoes a Schiff base addition with aldehydes of different origin.	tmpzr1t_l9r_go_relaxed.owl	isoquinoline alkaloid breakdown|isoquinoline alkaloid degradation|ipecac alkaloid catabolism|isoquinoline alkaloid catabolism							mah	2009-12-10T11:17:49Z					biological_process											owl:Class	
GO:1902895	biolink:NamedThing	positive regulation of pri-miRNA transcription by RNA polymerase II	Any process that activates or increases the frequency, rate or extent of pri-miRNA transcription mediated by RNA polymerase II.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of pri-miRNA transcription from RNA polymerase II promoter|positive regulation of pri-miRNA transcription from RNA polymerase II promoter|up regulation of pri-miRNA transcription from RNA polymerase II promoter|activation of pri-miRNA transcription from RNA polymerase II promoter|upregulation of pri-miRNA transcription from RNA polymerase II promoter							dph	2014-04-08T13:22:20Z					biological_process											owl:Class	
GO:1902893	biolink:NamedThing	regulation of pri-miRNA transcription by RNA polymerase II	Any process that modulates the frequency, rate or extent of pri-miRNA transcription mediated by RNA polymerase II.	tmpzr1t_l9r_go_relaxed.owl	regulation of pri-miRNA transcription from RNA polymerase II promoter							dph	2014-04-08T13:22:08Z					biological_process											owl:Class	
GO:0035889	biolink:NamedThing	otolith tethering	The attachment of a developing otolith to the kinocilia of tether cells in the inner ear.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-06-14T02:28:14Z					biological_process											owl:Class	
GO:0014057	biolink:NamedThing	positive regulation of acetylcholine secretion, neurotransmission	Any process that activates or increases the frequency, rate or extent of the regulated release of acetylcholine.	tmpzr1t_l9r_go_relaxed.owl	up regulation of acetylcholine secretion|upregulation of acetylcholine secretion|stimulation of acetylcholine secretion|activation of acetylcholine secretion|up-regulation of acetylcholine secretion													biological_process											owl:Class	
GO:0051954	biolink:NamedThing	positive regulation of amine transport	Any process that activates, maintains or increases the frequency, rate or extent of the directed movement of amines into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	upregulation of amine transport|activation of amine transport|up-regulation of amine transport|stimulation of amine transport|up regulation of amine transport													biological_process											owl:Class	
GO:0045612	biolink:NamedThing	positive regulation of hemocyte differentiation	Any process that activates or increases the frequency, rate or extent of hemocyte differentiation.	tmpzr1t_l9r_go_relaxed.owl	stimulation of hemocyte differentiation|up regulation of hemocyte differentiation|positive regulation of arthropod blood cell differentiation|upregulation of hemocyte differentiation|up-regulation of hemocyte differentiation|activation of hemocyte differentiation													biological_process											owl:Class	
GO:1905946	biolink:NamedThing	negative regulation of response to calcium ion	Any process that stops, prevents or reduces the frequency, rate or extent of response to calcium ion.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of response to Ca2+ ion|negative regulation of response to Ca2+ ion|down regulation of response to calcium ion|downregulation of response to calcium ion|downregulation of response to Ca2+ ion|inhibition of response to calcium ion|inhibition of response to Ca2+ ion|down-regulation of response to calcium ion|down regulation of response to Ca2+ ion							bc	2017-02-13T10:56:41Z					biological_process											owl:Class	
GO:0090209	biolink:NamedThing	negative regulation of triglyceride metabolic process	Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving triglyceride, any triester of glycerol.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-12-23T10:35:06Z					biological_process											owl:Class	
GO:0070520	biolink:NamedThing	alpha4-beta1 integrin-CD81 complex	A protein complex that consists of an alpha4-beta1 integrin complex bound to membrane protein CD81, a member of the tetraspan family.	tmpzr1t_l9r_go_relaxed.owl	ITGA4-ITGB1-CD81 complex													cellular_component											owl:Class	
GO:0044206	biolink:NamedThing	UMP salvage	Any process which produces UMP, uridine monophosphate, from derivatives of it (e.g. cytidine, uridine, cytosine) without de novo synthesis.	tmpzr1t_l9r_go_relaxed.owl	UMP biosynthesis via nucleoside salvage pathway|UMP biosynthetic process via nucleoside salvage pathway							jl	2009-10-21T11:32:33Z					biological_process											owl:Class	
GO:0072734	biolink:NamedThing	cellular response to staurosporine	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a staurosporine stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2012-07-17T10:33:00Z					biological_process											owl:Class	
GO:0072733	biolink:NamedThing	response to staurosporine	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a staurosporine stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2012-07-17T10:32:28Z					biological_process											owl:Class	
GO:0043288	biolink:NamedThing	apocarotenoid metabolic process	The chemical reactions and pathways involving apocarotenoids, a class of compounds derived from the oxidative cleavage of carotenoids, many of which are biologically important e.g. retinal and abscisic acid.	tmpzr1t_l9r_go_relaxed.owl	apocarotenoid metabolism|apo carotenoid metabolic process													biological_process											owl:Class	
GO:0006720	biolink:NamedThing	isoprenoid metabolic process	The chemical reactions and pathways involving isoprenoid compounds, isoprene (2-methylbuta-1,3-diene) or compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues.	tmpzr1t_l9r_go_relaxed.owl	polyterpene metabolic process|polyisoprenoid metabolic process|polyterpene metabolism|isoprenoid metabolism|polyisoprenoid metabolism											GO:0016096		biological_process											owl:Class	
GO:0032642	biolink:NamedThing	regulation of chemokine production	Any process that modulates the frequency, rate, or extent of chemokine production.	tmpzr1t_l9r_go_relaxed.owl	regulation of chemokine secretion|regulation of chemokine biosynthetic process								2009-12-18T11:28:00Z			GO:0090196|GO:0045073		biological_process											owl:Class	
GO:0002035	biolink:NamedThing	brain renin-angiotensin system	The process in which an angiotensin-mediated signaling system present in the brain regulates the force with which blood passes through the circulatory system.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0001976	biolink:NamedThing	nervous system process involved in regulation of systemic arterial blood pressure	The regulation of blood pressure mediated by detection of stimuli and a neurological response.	tmpzr1t_l9r_go_relaxed.owl	neurological system process involved in regulation of systemic arterial blood pressure|fast control of arterial pressure|blood pressure regulation by neurological process|neurological process involved in regulation of systemic arterial blood pressure													biological_process											owl:Class	
GO:0150034	biolink:NamedThing	distal axon	That part of an axon close to and including the growth cone or the axon terminus.	tmpzr1t_l9r_go_relaxed.owl	distal part of the axon|distal part of axon							bc	2018-02-19T15:04:24Z					cellular_component											owl:Class	
GO:0060617	biolink:NamedThing	positive regulation of mammary placode formation by mesenchymal-epithelial signaling	Any process that initiates the formation of a mammary placode through a mechanism that mediates the transfer of information from a mesenchymal cell to an epithelial cell resulting in the epithelial cell adopting the identity of a cell of the mammary placode.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of mammary placode formation by mesenchymal-epithelial signalling							dph	2009-05-18T09:16:07Z					biological_process											owl:Class	
GO:0010028	biolink:NamedThing	xanthophyll cycle	A cyclic series of interconversions involving three xanthophylls, violoxanthin, antheraxanthin, and zeaxanthin. The xanthophyll cycle is involved in regulating energy dissipation in light harvesting complex II.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:PWY-1141|Wikipedia:Xanthophyll#Xanthophyll_cycle									biological_process											owl:Class	
GO:0018589	biolink:NamedThing	di-n-butyltin dioxygenase activity	Catalysis of the reaction: dibutyltin + O2 + 2 H+ + 2 e- = H2O + beta-hydroxybutylbutyltin.	tmpzr1t_l9r_go_relaxed.owl	DBT dioxygenase activity				UM-BBD_reactionID:r0645									molecular_function											owl:Class	
GO:0006552	biolink:NamedThing	leucine catabolic process	The chemical reactions and pathways resulting in the breakdown of leucine, 2-amino-4-methylpentanoic acid.	tmpzr1t_l9r_go_relaxed.owl	leucine catabolism|leucine breakdown|leucine degradation				MetaCyc:LEU-DEG2-PWY									biological_process											owl:Class	
GO:0009083	biolink:NamedThing	branched-chain amino acid catabolic process	The chemical reactions and pathways resulting in the breakdown of amino acids containing a branched carbon skeleton, comprising isoleucine, leucine and valine.	tmpzr1t_l9r_go_relaxed.owl	branched chain family amino acid breakdown|branched chain family amino acid degradation|branched chain family amino acid catabolic process|branched chain family amino acid catabolism													biological_process											owl:Class	
GO:0106220	biolink:NamedThing	pyocyanine biosynthetic process	The chemical reactions and pathways resulting in the formation of pyrocyanin, an iminium betaine that is 5-methylphenazin-5-ium which is substituted at position 1 by an oxidanidyl group.	tmpzr1t_l9r_go_relaxed.owl	pyocyanin biosynthetic process							hjd	2019-08-19T17:15:48Z					biological_process											owl:Class	
GO:1900085	biolink:NamedThing	negative regulation of peptidyl-tyrosine autophosphorylation	Any process that stops, prevents or reduces the frequency, rate or extent of peptidyl-tyrosine autophosphorylation.	tmpzr1t_l9r_go_relaxed.owl	down regulation of receptor tyrosine kinase autophosphorylation|down regulation of peptidyl-tyrosine autophosphorylation|inhibition of tyrosine autophosphorylation|downregulation of peptidyl-tyrosine autophosphorylation|inhibition of receptor tyrosine kinase autophosphorylation|downregulation of receptor tyrosine kinase autophosphorylation|inhibition of peptidyl-tyrosine autophosphorylation|down-regulation of tyrosine autophosphorylation|down-regulation of peptidyl-tyrosine autophosphorylation|down-regulation of receptor tyrosine kinase autophosphorylation|negative regulation of receptor tyrosine kinase autophosphorylation|negative regulation of tyrosine autophosphorylation|down regulation of tyrosine autophosphorylation|downregulation of tyrosine autophosphorylation							bf	2012-02-03T10:17:12Z					biological_process											owl:Class	
GO:0031953	biolink:NamedThing	negative regulation of protein autophosphorylation	Any process that stops, prevents or decreases the rate of the phosphorylation by a protein of one or more of its own residues.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of protein amino acid autophosphorylation|downregulation of protein amino acid autophosphorylation|negative regulation of protein amino acid autophosphorylation|down regulation of protein amino acid autophosphorylation|inhibition of protein amino acid autophosphorylation													biological_process											owl:Class	
GO:0032303	biolink:NamedThing	regulation of icosanoid secretion	Any process that modulates the frequency, rate or extent of the controlled release of an icosanoid from a cell.	tmpzr1t_l9r_go_relaxed.owl	regulation of eicosanoid secretion													biological_process											owl:Class	
GO:0044070	biolink:NamedThing	regulation of anion transport	Any process that modulates the frequency, rate or extent of the directed movement of anions, atoms or small molecules with a net negative charge into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0072155	biolink:NamedThing	epithelial cell migration involved in nephron tubule morphogenesis	The orderly movement of epithelial cells within a renal tubule that contributes to nephron tubule morphogenesis.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-02-24T02:21:25Z					biological_process											owl:Class	
GO:1900143	biolink:NamedThing	positive regulation of oligodendrocyte apoptotic process	Any process that activates or increases the frequency, rate or extent of oligodendrocyte apoptotic process.	tmpzr1t_l9r_go_relaxed.owl	up regulation of oligodendrocyte apoptotic process|up regulation of oligodendrocyte apoptosis|activation of oligodendrocyte apoptotic process|activation of oligodendrocyte apoptosis|upregulation of oligodendrocyte apoptotic process|upregulation of oligodendrocyte apoptosis|up-regulation of oligodendrocyte apoptosis|positive regulation of oligodendrocyte apoptosis|up-regulation of oligodendrocyte apoptotic process							yaf	2012-03-06T10:22:54Z					biological_process											owl:Class	
GO:0034352	biolink:NamedThing	positive regulation of glial cell apoptotic process	Any process that activates or increases the frequency, rate, or extent of glial cell apoptotic process.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of glial cell apoptosis|stimulation of glial cell apoptosis|positive regulation of glial cell apoptosis|upregulation of glial cell apoptosis|activation of glial cell apoptosis|up regulation of glial cell apoptosis													biological_process											owl:Class	
GO:0071806	biolink:NamedThing	protein transmembrane transport	The process in which a protein is transported across a membrane.	tmpzr1t_l9r_go_relaxed.owl	protein membrane transport					Note that this term is not intended for use in annotating lateral movement within membranes.		mah	2010-09-03T02:54:26Z					biological_process											owl:Class	
GO:0047927	biolink:NamedThing	gibberellin-44 dioxygenase activity	Catalysis of the reaction: gibberellin 44 + 2-oxoglutarate + O2 = gibberellin 19 + succinate + CO2.	tmpzr1t_l9r_go_relaxed.owl	gibberellin A44 oxidase activity|(gibberellin-44), 2-oxoglutarate:oxygen oxidoreductase activity|(gibberellin-44),2-oxoglutarate:oxygen oxidoreductase activity|oxygenase, gibberellin A44 oxidase activity				EC:1.14.11.12|MetaCyc:RXN1F-168|RHEA:16033									molecular_function											owl:Class	
GO:0070722	biolink:NamedThing	Tle3-Aes complex	A transcriptional repressor complex that consists of a heterodimer of the proteins Tle3 (also known as Grg3b) and Aes (Grg5), which are homologs of the Drosophila groucho gene product.	tmpzr1t_l9r_go_relaxed.owl	Grg3b-Grg5 complex							mah	2009-06-10T05:45:28Z					cellular_component											owl:Class	
GO:0090571	biolink:NamedThing	RNA polymerase II transcription repressor complex	A protein complex, located in the nucleus, that possesses activity that prevents or downregulates transcription from a RNA polymerase II promoter.	tmpzr1t_l9r_go_relaxed.owl								tb	2014-05-09T13:26:16Z					cellular_component											owl:Class	
GO:1901685	biolink:NamedThing	glutathione derivative metabolic process	The chemical reactions and pathways involving glutathione derivative.	tmpzr1t_l9r_go_relaxed.owl	glutathione derivative metabolism							pr	2012-12-05T11:57:11Z					biological_process											owl:Class	
GO:1903556	biolink:NamedThing	negative regulation of tumor necrosis factor superfamily cytokine production	Any process that stops, prevents or reduces the frequency, rate or extent of tumor necrosis factor superfamily cytokine production.	tmpzr1t_l9r_go_relaxed.owl	downregulation of tumor necrosis factor superfamily cytokine production|downregulation of TNFSF cytokine production|down regulation of TNF superfamily production|down-regulation of tumor necrosis factor superfamily cytokine production|down regulation of TNFSF cytokine production|inhibition of TNFSF cytokine production|down-regulation of TNFSF cytokine production|down regulation of tumor necrosis factor superfamily cytokine production|inhibition of TNF superfamily production|inhibition of tumor necrosis factor superfamily cytokine production|negative regulation of TNFSF cytokine production|negative regulation of TNF superfamily production|down-regulation of TNF superfamily production|downregulation of TNF superfamily production							pga	2014-10-21T10:26:14Z					biological_process											owl:Class	
GO:1904518	biolink:NamedThing	protein localization to cytoplasmic microtubule plus-end	A process in which a protein is transported to, or maintained in, a location at a cytoplasmic microtubule plus-end.	tmpzr1t_l9r_go_relaxed.owl	protein localisation to cytoplasmic microtubule plus-end|protein localisation in cytoplasmic microtubule plus-end|protein localization in cytoplasmic microtubule plus-end							mah	2015-07-29T14:46:05Z					biological_process											owl:Class	
GO:1905755	biolink:NamedThing	protein localization to cytoplasmic microtubule	A process in which a protein is transported to, or maintained in, a location within a cytoplasmic microtubule.	tmpzr1t_l9r_go_relaxed.owl	protein localisation to cytoplasmic microtubule							mah	2016-12-12T15:31:07Z					biological_process											owl:Class	
GO:0030515	biolink:NamedThing	snoRNA binding	Binding to a small nucleolar RNA.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1900908	biolink:NamedThing	regulation of olefin metabolic process	Any process that modulates the frequency, rate or extent of olefin metabolic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of olefin metabolism							tt	2012-06-13T04:18:29Z					biological_process											owl:Class	
GO:0018216	biolink:NamedThing	peptidyl-arginine methylation	The addition of a methyl group to an arginine residue in a protein.	tmpzr1t_l9r_go_relaxed.owl												GO:0018017		biological_process											owl:Class	
GO:0036113	biolink:NamedThing	very long-chain fatty-acyl-CoA catabolic process	The chemical reactions and pathways resulting in the breakdown of very long-chain fatty-acyl-CoAs, any derivative of coenzyme A in which the sulfhydryl group is in a thioester linkage with a medium-chain fatty-acyl group. A very long-chain fatty acid is a fatty acid which has a chain length greater than C22.	tmpzr1t_l9r_go_relaxed.owl	very long-chain fatty-acyl-CoA catabolism|very long-chain fatty-acyl-CoA breakdown|very long-chain fatty-acyl-CoA degradation							bf	2012-02-15T11:16:11Z					biological_process											owl:Class	
GO:0036115	biolink:NamedThing	fatty-acyl-CoA catabolic process	The chemical reactions and pathways resulting in the breakdown of a fatty-acyl-CoA, any derivative of coenzyme A in which the sulfhydryl group is in thiolester linkage with a fatty-acyl group.	tmpzr1t_l9r_go_relaxed.owl	fatty-acyl-CoA catabolism|fatty-acyl-CoA degradation|fatty-acyl-CoA breakdown							bf	2012-02-15T11:26:25Z					biological_process											owl:Class	
GO:0002612	biolink:NamedThing	positive regulation of plasmacytoid dendritic cell antigen processing and presentation	Any process that activates or increases the frequency, rate, or extent of plasmacytoid dendritic cell antigen processing and presentation.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of plasmacytoid dendritic cell antigen processing and presentation|up regulation of plasmacytoid dendritic cell antigen processing and presentation|activation of plasmacytoid dendritic cell antigen processing and presentation|upregulation of plasmacytoid dendritic cell antigen processing and presentation|stimulation of plasmacytoid dendritic cell antigen processing and presentation													biological_process											owl:Class	
GO:0010831	biolink:NamedThing	positive regulation of myotube differentiation	Any process that activates, maintains or increases the frequency, rate or extent of myotube differentiation. Myotube differentiation is the process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1901416	biolink:NamedThing	regulation of response to ethanol	Any process that modulates the frequency, rate or extent of response to ethanol.	tmpzr1t_l9r_go_relaxed.owl								tt	2012-10-01T16:48:24Z					biological_process											owl:Class	
GO:0140266	biolink:NamedThing	Woronin body	Peroxisome-derived dense-core vesicle that seals septal pores upon hyphal lysis to prevent excessive cytoplasmic loss. It is specific to several genera of filamentous ascomycetes.	tmpzr1t_l9r_go_relaxed.owl								pg	2018-09-24T14:53:37Z					cellular_component											owl:Class	
GO:0042579	biolink:NamedThing	microbody	Cytoplasmic organelles, spherical or oval in shape, that are bounded by a single membrane and contain oxidative enzymes, especially those utilizing hydrogen peroxide (H2O2).	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Microbody									cellular_component											owl:Class	
GO:0002903	biolink:NamedThing	negative regulation of B cell apoptotic process	Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell apoptotic process.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of B cell apoptosis|down regulation of B cell apoptosis|down-regulation of B cell apoptosis|inhibition of B cell apoptosis|downregulation of B cell apoptosis													biological_process											owl:Class	
GO:0106091	biolink:NamedThing	glial cell projection elongation	The process of creating an elongation or projection from a glial cell.	tmpzr1t_l9r_go_relaxed.owl								hjd	2018-01-26T19:40:19Z					biological_process											owl:Class	
GO:0048858	biolink:NamedThing	cell projection morphogenesis	The process in which the anatomical structures of a cell projection are generated and organized.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0014873	biolink:NamedThing	response to muscle activity involved in regulation of muscle adaptation	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a muscle activity stimulus. This process occurs as part of the regulation of muscle adaptation.	tmpzr1t_l9r_go_relaxed.owl	response to fatigue|response to muscle activity involved in regulation of muscle plasticity													biological_process											owl:Class	
GO:0014874	biolink:NamedThing	response to stimulus involved in regulation of muscle adaptation	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. This occurs as part of the regulation of muscle adaptation.	tmpzr1t_l9r_go_relaxed.owl	response to stimulus involved in regulation of muscle plasticity													biological_process											owl:Class	
GO:0051134	biolink:NamedThing	negative regulation of NK T cell activation	Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer T cell activation.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of NT cell activation|negative regulation of natural killer T cell activation|negative regulation of natural T cell activation|negative regulation of NK T-lymphocyte activation|down regulation of NK T cell activation|negative regulation of NK T-cell activation|inhibition of NK T cell activation|down-regulation of NK T cell activation|negative regulation of NKT cell activation|negative regulation of NK T lymphocyte activation|downregulation of NK T cell activation													biological_process											owl:Class	
GO:0051133	biolink:NamedThing	regulation of NK T cell activation	Any process that modulates the frequency, rate or extent of natural killer T cell activation.	tmpzr1t_l9r_go_relaxed.owl	regulation of natural T cell activation|regulation of NT cell activation|regulation of natural killer T cell activation|regulation of NK T-cell activation|regulation of NKT cell activation|regulation of NK T-lymphocyte activation|regulation of NK T lymphocyte activation													biological_process											owl:Class	
GO:0070556	biolink:NamedThing	TAF4B-containing transcription factor TFIID complex	A transcription factor TFIID complex that contains the TBP-associated factor TAF4B (also known as TAFII105 in human), a cell-type-specific variant of TAF4.	tmpzr1t_l9r_go_relaxed.owl	TFIID complex, B-cell specific													cellular_component											owl:Class	
GO:0005669	biolink:NamedThing	transcription factor TFIID complex	A complex composed of TATA binding protein (TBP) and TBP associated factors (TAFs); the total mass is typically about 800 kDa. Most of the TAFs are conserved across species. In TATA-containing promoters for RNA polymerase II (Pol II), TFIID is believed to recognize at least two distinct elements, the TATA element and a downstream promoter element. TFIID is also involved in recognition of TATA-less Pol II promoters. Binding of TFIID to DNA is necessary but not sufficient for transcription initiation from most RNA polymerase II promoters.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:2000661	biolink:NamedThing	positive regulation of interleukin-1-mediated signaling pathway	Any process that activates or increases the frequency, rate or extent of interleukin-1-mediated signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of interleukin-1 alpha-mediated signaling pathway|positive regulation of interleukin-1-mediated signalling pathway|positive regulation of IL-1-mediated signaling pathway|positive regulation of IL-1 alpha-mediated signaling pathway|positive regulation of IL-1 beta-mediated signaling pathway|positive regulation of interleukin-1 beta-mediated signaling pathway							dph	2011-05-03T07:13:40Z					biological_process											owl:Class	
GO:0044196	biolink:NamedThing	host cell nucleolus	A small, dense body one or more of which are present in the nucleus of eukaryotic host cells.	tmpzr1t_l9r_go_relaxed.owl								jl	2009-10-20T02:37:07Z					cellular_component											owl:Class	
GO:0044094	biolink:NamedThing	host cell nuclear part	Any constituent part of a host cell's nucleus, a membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. The host is the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl						Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.		jl	2009-04-22T01:59:14Z					cellular_component											owl:Class	
GO:0050594	biolink:NamedThing	tabersonine 16-hydroxylase activity	Catalysis of the reaction: H(+) + NADPH + O(2) + tabersonine = 16-hydroxytabersonine + H(2)O + NADP(+).	tmpzr1t_l9r_go_relaxed.owl	tabersonine,NADPH:oxygen oxidoreductase (16-hydroxylating)				EC:1.14.14.103|KEGG_REACTION:R05855|RHEA:14133|MetaCyc:1.14.13.73-RXN									molecular_function											owl:Class	
GO:0140146	biolink:NamedThing	calcium ion import into vacuole	The directed movement of calcium cations into the vacuole across the vacuolar membrane.	tmpzr1t_l9r_go_relaxed.owl								pg	2017-12-13T15:15:29Z					biological_process											owl:Class	
GO:0034486	biolink:NamedThing	vacuolar transmembrane transport	The process in which a solute is transported from one side of the vacuolar membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	vacuolar membrane transport					Note that this term is not intended for use in annotating lateral movement within membranes.								biological_process											owl:Class	
GO:0035598	biolink:NamedThing	N6-threonylcarbomyladenosine methylthiotransferase activity	Catalysis of the methylthiolation (-SCH3 addition) at the C2 of the adenosine ring of N6-threonylcarbomyladenosine (t6A) in tRNA, to form 2-methylthio-N6-threonylcarbamoyladenosine (ms2t6A).	tmpzr1t_l9r_go_relaxed.owl	t6A methylthiotransferase activity				Reactome:R-HSA-6786571			bf	2010-11-12T01:28:32Z					molecular_function											owl:Class	
GO:0035596	biolink:NamedThing	methylthiotransferase activity	Catalysis of the addition of a methylthioether group (-SCH3) to a nucleic acid or protein acceptor.	tmpzr1t_l9r_go_relaxed.owl	MTTase							bf	2010-11-12T01:24:38Z					molecular_function											owl:Class	
GO:0050786	biolink:NamedThing	RAGE receptor binding	Binding to a RAGE receptor, the receptor for advanced glycation end-products.	tmpzr1t_l9r_go_relaxed.owl	advanced glycation end-product receptor binding													molecular_function											owl:Class	
GO:0046378	biolink:NamedThing	enterobacterial common antigen metabolic process	The chemical reactions and pathways involving enterobacterial common antigen, an acidic polysaccharide containing N-acetyl-D-glucosamine, N-acetyl-D-mannosaminouronic acid, and 4-acetamido-4,6-dideoxy-D-galactose. A major component of the cell wall outer membrane of Gram-negative bacteria.	tmpzr1t_l9r_go_relaxed.owl	enterobacterial common antigen metabolism													biological_process											owl:Class	
GO:0150101	biolink:NamedThing	regulation of microtubule anchoring at centrosome	Any process that modulates the frequency, rate or extent of microtubule anchoring at centrosome.	tmpzr1t_l9r_go_relaxed.owl								bc	2019-04-17T11:24:52Z					biological_process											owl:Class	
GO:1904856	biolink:NamedThing	cytolytic granule lumen	Any cytoplasmic membrane-bounded vesicle lumen that is part of a cytolytic granule.	tmpzr1t_l9r_go_relaxed.owl	cytoplasmic membrane-bounded vesicle lumen of cytolytic granule|cytoplasmic membrane-enclosed vesicle lumen of cytolytic granule|cytolytic granule cytoplasmic membrane-bounded vesicle lumen							mec	2015-12-15T12:51:17Z					cellular_component											owl:Class	
GO:0005775	biolink:NamedThing	vacuolar lumen	The volume enclosed within the vacuolar membrane.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0003019	biolink:NamedThing	central nervous system control of baroreceptor feedback	The neurological process in which nerve impulses arising in the aorta or the carotid sinuses travel to the medulla and reach the nucleus of tractus solaris.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0035490	biolink:NamedThing	regulation of leukotriene production involved in inflammatory response	Any process that modulates the rate, frequency or extent of the synthesis or release of any leukotriene following a stimulus as part of an inflammatory response.	tmpzr1t_l9r_go_relaxed.owl								bf	2010-04-26T10:49:22Z					biological_process											owl:Class	
GO:2000847	biolink:NamedThing	negative regulation of corticosteroid hormone secretion	Any process that stops, prevents or reduces the frequency, rate or extent of corticosteroid hormone secretion.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of corticosteroid secretion							bf	2011-07-26T08:43:42Z					biological_process											owl:Class	
GO:2000832	biolink:NamedThing	negative regulation of steroid hormone secretion	Any process that stops, prevents or reduces the frequency, rate or extent of steroid hormone secretion.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-07-26T08:38:50Z					biological_process											owl:Class	
GO:0004180	biolink:NamedThing	carboxypeptidase activity	Catalysis of the hydrolysis of a single C-terminal amino acid residue from a polypeptide chain.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/19681			RHEA:28783|Reactome:R-HSA-1247910									molecular_function											owl:Class	
GO:0008238	biolink:NamedThing	exopeptidase activity	Catalysis of the hydrolysis of a peptide bond not more than three residues from the N- or C-terminus of a polypeptide chain, in a reaction that requires a free N-terminal amino group, C-terminal carboxyl group or both.	tmpzr1t_l9r_go_relaxed.owl	exoprotease activity													molecular_function											owl:Class	
GO:0010641	biolink:NamedThing	positive regulation of platelet-derived growth factor receptor signaling pathway	Any process that increases the frequency, rate or extent of the platelet-derived growth factor receptor signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of platelet-derived growth factor receptor signalling pathway													biological_process											owl:Class	
GO:0010640	biolink:NamedThing	regulation of platelet-derived growth factor receptor signaling pathway	Any process that modulates the frequency, rate or extent of the platelet-derived growth factor receptor signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	regulation of platelet-derived growth factor receptor signalling pathway													biological_process											owl:Class	
GO:0140510	biolink:NamedThing	mitotic nuclear bridge	A narrow constricted region of the nucleus that forms around the anaphase spindle during closed mitosis, and connects the main portions of the newly forming daughter nuclei.	tmpzr1t_l9r_go_relaxed.owl	nuclear bridge							pg	2020-09-07T09:59:46Z					cellular_component											owl:Class	
GO:0050950	biolink:NamedThing	positive regulation of late stripe melanocyte differentiation	Any process that activates or increases the frequency, rate or extent of late stripe melanocyte differentiation.	tmpzr1t_l9r_go_relaxed.owl	stimulation of late stripe melanocyte differentiation|positive regulation of late stripe melanophore differentiation|upregulation of late stripe melanocyte differentiation|up regulation of late stripe melanocyte differentiation|activation of late stripe melanocyte differentiation|up-regulation of late stripe melanocyte differentiation													biological_process											owl:Class	
GO:0050940	biolink:NamedThing	regulation of late stripe melanocyte differentiation	Any process that modulates the frequency, rate or extent of late stripe melanocyte differentiation.	tmpzr1t_l9r_go_relaxed.owl	regulation of late stripe melanophore differentiation													biological_process											owl:Class	
GO:0043976	biolink:NamedThing	histone H3-K79 acetylation	The modification of histone H3 by the addition of an acetyl group to a lysine residue at position 79 of the histone.	tmpzr1t_l9r_go_relaxed.owl	histone H3 acetylation at K79|histone H3K79 acetylation													biological_process											owl:Class	
GO:0046651	biolink:NamedThing	lymphocyte proliferation	The expansion of a lymphocyte population by cell division.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0006786	biolink:NamedThing	heme C biosynthetic process	The chemical reactions and pathways resulting in the formation of heme c, a derivative of heme found in cytochromes c, b4, and f.	tmpzr1t_l9r_go_relaxed.owl	heme C formation|heme C biosynthesis|heme C anabolism|heme C synthesis|haem C biosynthetic process|haem C biosynthesis													biological_process											owl:Class	
GO:0046162	biolink:NamedThing	heme C metabolic process	The chemical reactions and pathways involving heme c, a derivative of heme found in cytochromes c, b4, and f.	tmpzr1t_l9r_go_relaxed.owl	haem C metabolism|heme C metabolism|haem C metabolic process													biological_process											owl:Class	
GO:0009964	biolink:NamedThing	negative regulation of flavonoid biosynthetic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of flavonoids.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of flavonoid biosynthetic process|negative regulation of flavonoid formation|down regulation of flavonoid biosynthetic process|negative regulation of flavonoid anabolism|inhibition of flavonoid biosynthetic process|negative regulation of flavonoid biosynthesis|negative regulation of flavonoid synthesis|downregulation of flavonoid biosynthetic process													biological_process											owl:Class	
GO:0033183	biolink:NamedThing	negative regulation of histone ubiquitination	Any process that stops, prevents, or reduces the frequency, rate or extent of the addition of a ubiquitin group to a histone protein.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0033189	biolink:NamedThing	response to vitamin A	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin A stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to retinol													biological_process											owl:Class	
GO:0045582	biolink:NamedThing	positive regulation of T cell differentiation	Any process that activates or increases the frequency, rate or extent of T cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of T cell development|upregulation of T cell differentiation|positive regulation of T-lymphocyte differentiation|positive regulation of T-cell differentiation|stimulation of T cell differentiation|activation of T cell differentiation|up-regulation of T cell differentiation|up regulation of T cell differentiation|positive regulation of T lymphocyte differentiation					Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.								biological_process											owl:Class	
GO:0047934	biolink:NamedThing	glucose 1-dehydrogenase (NAD+) activity	Catalysis of the reaction: D-glucose + NAD+ = D-glucono-1,5-lactone + NADH.	tmpzr1t_l9r_go_relaxed.owl	D-glucose:NAD oxidoreductase activity|D-glucose:NAD+ 1-oxidoreductase activity|D-aldohexose dehydrogenase activity				EC:1.1.1.118|MetaCyc:GLUCOSE-1-DEHYDROGENASE-NAD+-RXN|RHEA:14293									molecular_function											owl:Class	
GO:0047936	biolink:NamedThing	glucose 1-dehydrogenase [NAD(P)] activity	Catalysis of the reaction: beta-D-glucose + NAD(P)+ = D-glucono-1,5-lactone + NAD(P)H.	tmpzr1t_l9r_go_relaxed.owl	beta-D-glucose:NAD(P)+ 1-oxidoreductase activity|hexose phosphate dehydrogenase activity|D-glucose dehydrogenase (NAD(P))				EC:1.1.1.47|MetaCyc:GLUCOSE-1-DEHYDROGENASE-RXN									molecular_function											owl:Class	
GO:1904075	biolink:NamedThing	positive regulation of trophectodermal cell proliferation	Any process that activates or increases the frequency, rate or extent of trophectodermal cell proliferation.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of trophectodermal cell proliferation|up-regulation of trophectoderm cell proliferation|upregulation of trophectoderm cell proliferation|positive regulation of trophectoderm cell proliferation|upregulation of trophectodermal cell proliferation|up regulation of trophectoderm cell proliferation|up regulation of trophectodermal cell proliferation|activation of trophectoderm cell proliferation|activation of trophectodermal cell proliferation							tb	2015-03-20T16:56:08Z					biological_process											owl:Class	
GO:0030854	biolink:NamedThing	positive regulation of granulocyte differentiation	Any process that activates or increases the frequency, rate or extent of granulocyte differentiation.	tmpzr1t_l9r_go_relaxed.owl	activation of granulocyte differentiation|up-regulation of granulocyte differentiation|stimulation of granulocyte differentiation|up regulation of granulocyte differentiation|upregulation of granulocyte differentiation													biological_process											owl:Class	
GO:0006648	biolink:NamedThing	dihydrosphingosine-1-P pathway	A phosphatidylethanolamine biosynthetic process that proceeds via the enzymatic action of dihydrosphingosine phosphate lyase.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0006646	biolink:NamedThing	phosphatidylethanolamine biosynthetic process	The chemical reactions and pathways resulting in the formation of phosphatidylethanolamine, any of a class of glycerophospholipids in which a phosphatidyl group is esterified to the hydroxyl group of ethanolamine.	tmpzr1t_l9r_go_relaxed.owl	phosphatidylethanolamine biosynthesis|phosphatidylethanolamine formation|phosphatidylethanolamine synthesis|phosphatidylethanolamine anabolism													biological_process											owl:Class	
GO:0043132	biolink:NamedThing	NAD transport	The directed movement of nicotinamide adenine dinucleotide into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore; transport may be of either the oxidized form, NAD, or the reduced form, NADH.	tmpzr1t_l9r_go_relaxed.owl	oxidized nicotinamide adenine dinucleotide transport|NAD (oxidized) transport|reduced NAD transport|oxidized NAD transport|reduced nicotinamide adenine dinucleotide transport|NAD (reduced) transport|NADH transport|nicotinamide adenine dinucleotide transport													biological_process											owl:Class	
GO:0006862	biolink:NamedThing	nucleotide transport	The directed movement of a nucleotide, any compound consisting of a nucleoside that is esterified with (ortho)phosphate, into, out of or within a cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0061314	biolink:NamedThing	Notch signaling involved in heart development	The series of molecular signals initiated by binding of an extracellular ligand to a Notch receptor on the surface of the target cell and contributing to the progression of the heart over time.	tmpzr1t_l9r_go_relaxed.owl	Notch signalling involved in heart development							dph	2010-09-24T08:25:22Z					biological_process											owl:Class	
GO:0043858	biolink:NamedThing	arginine:ornithine antiporter activity	Catalysis of the reaction: arginine(out) + ornithine(in) = arginine(in) + ornithine(out).	tmpzr1t_l9r_go_relaxed.owl	ArcD|arginine-ornithine antiporter activity|arginine/ornithine antiporter activity													molecular_function											owl:Class	
GO:0019296	biolink:NamedThing	coenzyme M metabolic process	The chemical reactions and pathways involving coenzyme M (2-thioethansulfonate), a coenzyme involved in the utilization of methane by methanogenic prokaryotes.	tmpzr1t_l9r_go_relaxed.owl	coenzyme M metabolism													biological_process											owl:Class	
GO:0035894	biolink:NamedThing	positive regulation of platelet aggregation in other organism	Any process in which an organism activates, maintains or increases the frequency, rate or extent of platelet aggregation in another organism.	tmpzr1t_l9r_go_relaxed.owl	upregulation of platelet aggregation in other organism|up-regulation of platelet aggregation in other organism							bf	2011-06-15T02:28:46Z					biological_process											owl:Class	
GO:1901731	biolink:NamedThing	positive regulation of platelet aggregation	Any process that activates or increases the frequency, rate or extent of platelet aggregation. Platelet aggregation is the adhesion of one platelet to one or more other platelets via adhesion molecules.	tmpzr1t_l9r_go_relaxed.owl	activation of platelet aggregation|upregulation of blood platelet aggregation|activation of thrombocyte aggregation|upregulation of thrombocyte aggregation|activation of blood platelet aggregation|up-regulation of thrombocyte aggregation|positive regulation of thrombocyte aggregation|positive regulation of blood platelet aggregation|upregulation of platelet aggregation|up regulation of thrombocyte aggregation|up-regulation of platelet aggregation|up regulation of platelet aggregation|up regulation of blood platelet aggregation|up-regulation of blood platelet aggregation							pr	2013-01-10T13:25:39Z					biological_process											owl:Class	
GO:0080038	biolink:NamedThing	positive regulation of cytokinin-activated signaling pathway	Any process that activates or increases the frequency, rate or extent of cytokinin signaling.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of cytokinin mediated signalling|positive regulation of cytokinin mediated signaling pathway													biological_process											owl:Class	
GO:0080036	biolink:NamedThing	regulation of cytokinin-activated signaling pathway	Any process that modulates the frequency, rate or extent of cytokinin signaling.	tmpzr1t_l9r_go_relaxed.owl	regulation of cytokinin mediated signalling|regulation of cytokinin mediated signaling pathway													biological_process											owl:Class	
GO:0047028	biolink:NamedThing	6-pyruvoyltetrahydropterin 2'-reductase activity	Catalysis of the reaction: NADP+ + 6-lactoyl-5,6,7,8-tetrahydropterin = NADPH + H+ + 6-pyruvoyltetrahydropterin.	tmpzr1t_l9r_go_relaxed.owl	6-pyruvoyl-tetrahydropterin 2'-reductase activity|6-pyruvoyltetrahydropterin reductase activity|6-lactoyl-5,6,7,8-tetrahydropterin:NADP+ 2'-oxidoreductase activity|pyruvoyl-tetrahydropterin reductase activity|6-pyruvoyl tetrahydropterin (2'-oxo)reductase activity|6PPH4(2'-oxo) reductase activity				EC:1.1.1.220|RHEA:11772|MetaCyc:1.1.1.220-RXN									molecular_function											owl:Class	
GO:1903482	biolink:NamedThing	positive regulation of actin filament organization involved in mitotic actomyosin contractile ring assembly	Any process that activates or increases the frequency, rate or extent of actin filament organization involved in mitotic actomyosin contractile ring assembly.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of actin filament organisation involved in contractile ring assembly involved in mitotic cytokinesis|up-regulation of actin filament organisation involved in mitotic actomyosin contractile ring assembly|up regulation of actin filament organisation involved in mitotic actomyosin contractile ring assembly|positive regulation of actin filament organisation involved in mitotic actomyosin contractile ring assembly|up regulation of actin filament organization involved in mitotic actomyosin contractile ring assembly|positive regulation of actin filament organisation involved in contractile ring assembly involved in mitotic cytokinesis|up-regulation of actin filament organization involved in mitotic actomyosin contractile ring assembly|activation of actin filament organization involved in mitotic actomyosin contractile ring assembly|up regulation of actin filament organisation involved in contractile ring assembly involved in mitotic cytokinesis|upregulation of actin filament organization involved in mitotic actomyosin contractile ring assembly|upregulation of actin filament organisation involved in contractile ring assembly involved in mitotic cytokinesis|upregulation of actin filament organisation involved in mitotic actomyosin contractile ring assembly|activation of actin filament organisation involved in mitotic actomyosin contractile ring assembly|activation of actin filament organisation involved in contractile ring assembly involved in mitotic cytokinesis							vw	2014-09-23T16:03:59Z					biological_process											owl:Class	
GO:1903480	biolink:NamedThing	regulation of actin filament organization involved in mitotic actomyosin contractile ring assembly	Any process that modulates the frequency, rate or extent of actin filament organization involved in mitotic actomyosin contractile ring assembly.	tmpzr1t_l9r_go_relaxed.owl	regulation of actin filament organisation involved in mitotic actomyosin contractile ring assembly|regulation of actin filament organisation involved in contractile ring assembly involved in mitotic cytokinesis							vw	2014-09-23T16:03:42Z					biological_process											owl:Class	
GO:0002878	biolink:NamedThing	negative regulation of acute inflammatory response to non-antigenic stimulus	Any process that stops, prevents, or reduces the frequency, rate, or extent of an acute inflammatory response to a non-antigenic stimulus.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of acute inflammatory response to non-antigenic stimulus|downregulation of acute inflammatory response to non-antigenic stimulus|down regulation of acute inflammatory response to non-antigenic stimulus|inhibition of acute inflammatory response to non-antigenic stimulus													biological_process											owl:Class	
GO:0002674	biolink:NamedThing	negative regulation of acute inflammatory response	Any process that stops, prevents, or reduces the frequency, rate, or extent of an acute inflammatory response.	tmpzr1t_l9r_go_relaxed.owl	downregulation of acute inflammatory response|down regulation of acute inflammatory response|inhibition of acute inflammatory response|down-regulation of acute inflammatory response													biological_process											owl:Class	
GO:1900609	biolink:NamedThing	F-9775A metabolic process	The chemical reactions and pathways involving F-9775A.	tmpzr1t_l9r_go_relaxed.owl	F-9775A metabolism							di	2012-05-15T07:02:27Z					biological_process											owl:Class	
GO:2001141	biolink:NamedThing	regulation of RNA biosynthetic process	Any process that modulates the frequency, rate or extent of RNA biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of RNA biosynthesis|regulation of RNA formation|regulation of RNA synthesis|regulation of RNA anabolism							dph	2011-10-17T11:36:25Z					biological_process											owl:Class	
GO:1905125	biolink:NamedThing	positive regulation of glucosylceramidase activity	Any process that activates or increases the frequency, rate or extent of glucosylceramidase activity.	tmpzr1t_l9r_go_relaxed.owl	up regulation of glucocerebrosidase activity|upregulation of beta-glucocerebrosidase activity|upregulation of psychosine hydrolase activity|activation of psychosine hydrolase activity|up-regulation of beta-D-glucocerebrosidase activity|positive regulation of GlcCer-beta-glucosidase activity|activation of beta-D-glucocerebrosidase activity|activation of beta-glucocerebrosidase activity|upregulation of glucosylsphingosine beta-D-glucosidase activity|upregulation of beta-glucosylceramidase activity|activation of glucosylsphingosine beta-D-glucosidase activity|up regulation of beta-glucosylceramidase activity|positive regulation of D-glucosyl-N-acylsphingosine glucohydrolase activity|upregulation of glucosphingosine glucosylhydrolase activity|up-regulation of ceramide glucosidase activity|positive regulation of GCase activity|up-regulation of glucosylsphingosine beta-D-glucosidase activity|up regulation of GlcCer-beta-glucosidase activity|activation of glucosylcerebrosidase activity|positive regulation of beta-glucosylceramidase activity|up regulation of ceramide glucosidase activity|positive regulation of glucosphingosine glucosylhydrolase activity|upregulation of glucosylsphingosine beta-glucosidase activity|up regulation of glucosylceramidase activity|up-regulation of D-glucosyl-N-acylsphingosine glucohydrolase activity|activation of GlcCer-beta-glucosidase activity|upregulation of acid beta-glucosidase activity|up regulation of glucosylsphingosine beta-glucosidase activity|up-regulation of GlcCer-beta-glucosidase activity|positive regulation of glucocerebrosidase activity|up regulation of beta-D-glucocerebrosidase activity|upregulation of beta-D-glucocerebrosidase activity|up-regulation of glucosylceramidase activity|upregulation of ceramide glucosidase activity|up-regulation of glucosylcerebrosidase activity|up-regulation of beta-glucocerebrosidase activity|up-regulation of glucosylsphingosine beta-glucosidase activity|positive regulation of beta-glucocerebrosidase activity|up regulation of D-glucosyl-N-acylsphingosine glucohydrolase activity|up regulation of glucosylsphingosine beta-D-glucosidase activity|activation of beta-glucosylceramidase activity|activation of glucocerebrosidase activity|up-regulation of glucosphingosine glucosylhydrolase activity|upregulation of glucosylceramidase activity|activation of glucosylsphingosine beta-glucosidase activity|positive regulation of ceramide glucosidase activity|activation of glucosphingosine glucosylhydrolase activity|positive regulation of glucosylsphingosine beta-D-glucosidase activity|activation of ceramide glucosidase activity|up-regulation of psychosine hydrolase activity|activation of acid beta-glucosidase activity|up-regulation of glucocerebrosidase activity|positive regulation of glucosylcerebrosidase activity|positive regulation of acid beta-glucosidase activity|upregulation of glucosylcerebrosidase activity|up regulation of acid beta-glucosidase activity|up regulation of psychosine hydrolase activity|upregulation of glucocerebrosidase activity|up regulation of glucosphingosine glucosylhydrolase activity|upregulation of D-glucosyl-N-acylsphingosine glucohydrolase activity|up regulation of beta-glucocerebrosidase activity|up-regulation of acid beta-glucosidase activity|positive regulation of beta-D-glucocerebrosidase activity|activation of D-glucosyl-N-acylsphingosine glucohydrolase activity|positive regulation of glucosylsphingosine beta-glucosidase activity|up regulation of glucosylcerebrosidase activity|activation of glucosylceramidase activity|upregulation of GlcCer-beta-glucosidase activity|positive regulation of psychosine hydrolase activity|up-regulation of beta-glucosylceramidase activity							bf	2016-04-11T15:44:43Z					biological_process											owl:Class	
GO:1905123	biolink:NamedThing	regulation of glucosylceramidase activity	Any process that modulates the frequency, rate or extent of glucosylceramidase activity.	tmpzr1t_l9r_go_relaxed.owl	regulation of glucosylsphingosine beta-glucosidase activity|regulation of glucosphingosine glucosylhydrolase activity|regulation of beta-D-glucocerebrosidase activity|regulation of psychosine hydrolase activity|regulation of GlcCer-beta-glucosidase activity|regulation of glucocerebrosidase activity|regulation of acid beta-glucosidase activity|regulation of GCase activity|regulation of D-glucosyl-N-acylsphingosine glucohydrolase activity|regulation of glucosylsphingosine beta-D-glucosidase activity|regulation of glucosylcerebrosidase activity|regulation of ceramide glucosidase activity|regulation of beta-glucocerebrosidase activity|regulation of beta-glucosylceramidase activity							bf	2016-04-11T15:44:26Z					biological_process											owl:Class	
GO:1903353	biolink:NamedThing	regulation of nucleus organization	Any process that modulates the frequency, rate or extent of nucleus organization.	tmpzr1t_l9r_go_relaxed.owl	regulation of nuclear organization and biogenesis|regulation of nuclear organisation|regulation of nucleus organization and biogenesis|regulation of nuclear organization|regulation of nuclear morphology							hjd	2014-08-20T19:36:16Z					biological_process											owl:Class	
GO:0009910	biolink:NamedThing	negative regulation of flower development	Any process that stops, prevents, or reduces the frequency, rate or extent of flower development.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of flower development|downregulation of flower development|inhibition of flower development|down regulation of flower development													biological_process											owl:Class	
GO:0002910	biolink:NamedThing	positive regulation of peripheral B cell deletion	Any process that activates or increases the frequency, rate, or extent of peripheral B cell deletion.	tmpzr1t_l9r_go_relaxed.owl	stimulation of peripheral B cell deletion|up-regulation of peripheral B cell deletion|upregulation of peripheral B cell deletion|up regulation of peripheral B cell deletion|activation of peripheral B cell deletion													biological_process											owl:Class	
GO:0044491	biolink:NamedThing	positive regulation of molecular function in other organism	Any process that activates or increases the frequency, rate or extent of the function of proteins in a second organism.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-02-01T12:21:51Z					biological_process											owl:Class	
GO:0044359	biolink:NamedThing	modulation of molecular function in other organism	The process in which an organism effects a change in the function of proteins in a second organism.	tmpzr1t_l9r_go_relaxed.owl								jl	2011-10-27T01:28:16Z					biological_process											owl:Class	
GO:1905310	biolink:NamedThing	regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis	Any process that modulates the frequency, rate or extent of cardiac neural crest cell migration involved in outflow tract morphogenesis.	tmpzr1t_l9r_go_relaxed.owl								rl	2016-07-11T17:34:26Z					biological_process											owl:Class	
GO:1990812	biolink:NamedThing	growth cone filopodium	A thin, stiff protrusion extended by the leading edge of an axonal or dendritic growth cone.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-07-24T22:35:16Z					cellular_component											owl:Class	
GO:1905669	biolink:NamedThing	TORC1 complex assembly	The aggregation, arrangement and bonding together of a set of components to form a TORC1 complex.	tmpzr1t_l9r_go_relaxed.owl	nutrient sensitive complex assembly|TOR complex 1 formation|rapamycin and nutrient-sensitive TOR complex formation|nutrient sensitive complex formation|TOR complex 1 assembly|dTOR/dRaptor complex formation|dTORC1 assembly|mTORC1 formation|TORC 1 complex formation|dTOR/dRaptor complex assembly|mTORC1 assembly|TORC 1 complex assembly|TORC1 assembly|rapamycin and nutrient-sensitive TOR complex assembly|dTORC1 formation|TORC1 complex formation|TORC1 formation							kmv	2016-11-11T21:03:27Z					biological_process											owl:Class	
GO:0001410	biolink:NamedThing	chlamydospore formation	The process whose specific outcome is the progression of the chlamydospore over time, from its formation to the mature structure. A chlamydospores is a mitotic (asexual) one-celled spore, produced primarily for survival, not dispersal, originating endogenously and singly within part of a pre-existing cell and possessing an inner secondary and often thickened cell wall. An example of this is found in Candida albicans.	tmpzr1t_l9r_go_relaxed.owl	chlamydospore development											GO:0055027		biological_process											owl:Class	
GO:0045437	biolink:NamedThing	uridine nucleosidase activity	Catalysis of the reaction: H(2)O + uridine = ribofuranose + uracil.	tmpzr1t_l9r_go_relaxed.owl	uridine hydrolase activity|uridine ribohydrolase activity				KEGG_REACTION:R01080|EC:3.2.2.3|MetaCyc:URIDINE-NUCLEOSIDASE-RXN|RHEA:15577									molecular_function											owl:Class	
GO:0050263	biolink:NamedThing	ribosylpyrimidine nucleosidase activity	Catalysis of the reaction: an N-D-ribosylpyrimidine + H2O = D-ribose + a pyrimidine.	tmpzr1t_l9r_go_relaxed.owl	pyrimidine nucleosidase activity|N-ribosylpyrimidine nucleosidase activity|RihB|nucleoside ribohydrolase activity|YeiK|N-ribosylpyrimidine ribohydrolase activity|pyrimidine-nucleoside ribohydrolase activity				EC:3.2.2.8|MetaCyc:RIBOSYLPYRIMIDINE-NUCLEOSIDASE-RXN|RHEA:56816									molecular_function											owl:Class	
GO:0048391	biolink:NamedThing	intermediate mesoderm formation	The process that gives rise to the intermediate mesoderm. This process pertains to the initial formation of the structure from unspecified parts.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0001707	biolink:NamedThing	mesoderm formation	The process that gives rise to the mesoderm. This process pertains to the initial formation of the structure from unspecified parts.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1904970	biolink:NamedThing	brush border assembly	The aggregation, arrangement and bonding together of adjacent microvilli through the formation of Ca(2+)-dependent adhesion links between them, forming a brush border.	tmpzr1t_l9r_go_relaxed.owl	brush border formation							tb	2016-02-17T00:58:30Z					biological_process											owl:Class	
GO:0019119	biolink:NamedThing	phenanthrene-9,10-epoxide hydrolase activity	Catalysis of the reaction: phenanthrene-9,10-oxide + H2O = trans-9,10-dihydrodiolphenanthrene.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0019118	biolink:NamedThing	phenanthrene-epoxide hydrolase activity	Catalysis of the reaction: a phenanthrene dioxide + H2O = a dihydrodiolphenanthrene.	tmpzr1t_l9r_go_relaxed.owl					EC:3.3.2.-									molecular_function											owl:Class	
GO:0016661	biolink:NamedThing	oxidoreductase activity, acting on other nitrogenous compounds as donors	Catalysis of an oxidation-reduction (redox) reaction in which a nitrogenous group, excluding NH and NH2 groups, acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.	tmpzr1t_l9r_go_relaxed.owl	oxidoreductase activity, acting on other nitrogenous compounds as donors, other acceptors				EC:1.7.-.-									molecular_function											owl:Class	
GO:0098673	biolink:NamedThing	inhibition of host DNA replication by virus	Any process by which a virus inhibits DNA replication in its host cell.  Some bacteriophages are known to do this, possibly as a way of increasing the pool of nucleotides available for virus replication.	tmpzr1t_l9r_go_relaxed.owl								dos	2017-01-17T15:58:15Z					biological_process											owl:Class	
GO:1903340	biolink:NamedThing	positive regulation of cell wall organization or biogenesis	Any process that activates or increases the frequency, rate or extent of cell wall organization or biogenesis.	tmpzr1t_l9r_go_relaxed.owl	up regulation of cell wall organisation or biogenesis|up-regulation of cell wall organization or biogenesis at cellular level|activation of cell wall organisation or biogenesis|up regulation of cellular cell wall organization or biogenesis|up regulation of cell wall organization or biogenesis at cellular level|activation of cell wall organization or biogenesis|up regulation of cell wall organization or biogenesis|upregulation of cell wall organization or biogenesis at cellular level|positive regulation of cell wall organisation or biogenesis|up-regulation of cell wall organisation or biogenesis|upregulation of cellular cell wall organization or biogenesis|activation of cellular cell wall organization or biogenesis|up-regulation of cellular cell wall organisation or biogenesis|up-regulation of cell wall organization or biogenesis|upregulation of cell wall organization or biogenesis|positive regulation of cellular cell wall organisation or biogenesis|upregulation of cellular cell wall organisation or biogenesis|up regulation of cellular cell wall organisation or biogenesis|up-regulation of cellular cell wall organization or biogenesis|activation of cellular cell wall organisation or biogenesis|positive regulation of cell wall organization or biogenesis at cellular level|activation of cell wall organization or biogenesis at cellular level|upregulation of cell wall organisation or biogenesis|positive regulation of cellular cell wall organization or biogenesis							vw	2014-08-18T13:21:06Z					biological_process											owl:Class	
GO:1900870	biolink:NamedThing	tatiopterin biosynthetic process	The chemical reactions and pathways resulting in the formation of tatiopterin.	tmpzr1t_l9r_go_relaxed.owl	tatiopterin biosynthesis|tatiopterin anabolism|tatiopterin synthesis|tatiopterin formation							tt	2012-06-12T04:44:19Z					biological_process											owl:Class	
GO:0039535	biolink:NamedThing	regulation of RIG-I signaling pathway	Any process that modulates the frequency, rate or extent of the series of molecular signals generated as a consequence of the cytoplasmic pattern recognition receptor (PRR) RIG-1 (also known as DDX58) binding to viral RNA.	tmpzr1t_l9r_go_relaxed.owl	regulation of retinoic acid inducible gene I signaling pathway|regulation of DDX58 signaling pathway|regulation of RIG-I signalling pathway							bf	2012-01-03T11:24:29Z					biological_process											owl:Class	
GO:0039531	biolink:NamedThing	regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway	Any process that modulates the frequency, rate or extent of the series of molecular signals generated as a consequence of a virus or viral RNA binding to a pattern recognition receptor (PRR) located in the cytoplasm.	tmpzr1t_l9r_go_relaxed.owl	regulation of MAV signaling|regulation of viral-induced cytoplasmic pattern recognition receptor signalling pathway							bf	2012-01-03T11:06:56Z					biological_process											owl:Class	
GO:0098695	biolink:NamedThing	inositol 1,4,5-trisphosphate receptor activity involved in regulation of postsynaptic cytosolic calcium levels	Any inositol 1,4,5-trisphosphate receptor activity that is involved in regulation of postsynaptic cytosolic calcium ion concentration.	tmpzr1t_l9r_go_relaxed.owl	IP3 receptor activity involved in regulation of postsynaptic cytosolic calcium levels							dos	2017-04-04T17:07:09Z					molecular_function											owl:Class	
GO:0005220	biolink:NamedThing	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity	Enables the transmembrane transfer of a calcium ion by a channel that opens when inositol 1,4,5-trisphosphate (IP3) has been bound by the channel complex or one of its constituent parts.	tmpzr1t_l9r_go_relaxed.owl	InsP3 receptor|IP3 receptor activity|inositol-1,4,5-trisphosphate receptor activity											GO:0008095		molecular_function											owl:Class	
GO:0005666	biolink:NamedThing	RNA polymerase III complex	RNA polymerase III, one of three nuclear DNA-directed RNA polymerases found in all eukaryotes, is a multisubunit complex; typically it produces 5S rRNA, tRNAs and some of the small nuclear RNAs. Two large subunits comprise the most conserved portion including the catalytic site and share similarity with other eukaryotic and bacterial multisubunit RNA polymerases. The remainder of the complex is composed of smaller subunits (generally ten or more), some of which are also found in RNA polymerase I and others of which are also found in RNA polymerases I and II. Although the core is competent to mediate ribonucleic acid synthesis, it requires additional factors to select the appropriate template.	tmpzr1t_l9r_go_relaxed.owl	DNA-directed RNA polymerase III complex|DNA-directed RNA polymerase III activity													cellular_component											owl:Class	
GO:0055029	biolink:NamedThing	nuclear DNA-directed RNA polymerase complex	A protein complex, located in the nucleus, that possesses DNA-directed RNA polymerase activity.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0086024	biolink:NamedThing	adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate	An adrenergic receptor signaling pathway that contributes to an increase in frequency or rate of heart contraction. Binding of adrenalin or noradrenalin to a beta-adrenergic receptor on the surface of the signal-receiving cell results in the activation of an intracellular Gs protein. Gs activates adenylate cyclase to increase intracellular cyclic-AMP (cAMP) levels. cAMP binds directly to F-channels to allow an inward flow of sodium (known as funny current, or If current). The funny current is responsible for membrane depolarization and an increase in heart rate.	tmpzr1t_l9r_go_relaxed.owl	adrenergic receptor signaling pathway involved in positive regulation of heart rate|beta adrenergic receptor signaling pathway involved in positive regulation of heart rate|activation of funny current by beta-adrenergic receptor signaling pathway|Gs-coupled adrenergic receptor signaling pathway involved in positive regulation of heart rate|adenylate cyclase-activating cardiac adrenergic receptor signaling pathway|adrenergic receptor signalling pathway involved in positive regulation of heart rate|If activation by beta-adrenergic receptor signaling pathway							tb	2011-11-10T09:38:49Z					biological_process											owl:Class	
GO:0001996	biolink:NamedThing	positive regulation of heart rate by epinephrine-norepinephrine	The process in which the presence of epinephrine or norepinephrine in the bloodstream activates, maintains or increases the rate of heart contraction.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of heart contraction rate by adrenaline-noradrenaline|positive regulation of heart contraction rate by epinephrine-norepinephrine|positive regulation of cardiac contraction rate by epinephrine-norepinephrine|increased chronotropy by epinephrine-norepinephrine|stimulation of heart contraction rate by epinephrine-norepinephrine|up regulation of heart contraction rate by epinephrine-norepinephrine|positive control of heart contraction rate by epinephrine-norepinephrine|upregulation of heart contraction rate by epinephrine-norepinephrine|up-regulation of heart contraction rate by epinephrine-norepinephrine|activation of heart contraction rate by epinephrine-norepinephrine													biological_process											owl:Class	
GO:0050501	biolink:NamedThing	hyaluronan synthase activity	Catalysis of the reaction: UDP-D-glucuronate + UDP-N-acetyl-D-glucosamine = [beta-N-acetyl-D-glucosaminyl-(1->4)-beta-D-glucuronosyl-(1->3)](n) + 2n UDP.	tmpzr1t_l9r_go_relaxed.owl	alternating UDP-alpha-N-acetyl-D-glucosamine:beta-D-glucuronosyl-(1,3)-[nascent hyaluronan] 4-N-acetyl-beta-D-glucosaminyltransferase and UDP-alpha-D-glucuronate:N-acetyl-beta-D-glucosaminyl-(1,4)-[nascent hyaluronan] 3-beta-D-glucuronosyltransferase activity|HAS activity|alternating UDP-alpha-N-acetyl-D-glucosamine:beta-D-glucuronosyl-(1->3)-[nascent hyaluronan] 4-N-acetyl-beta-D-glucosaminyltransferase and UDP-alpha-D-glucuronate:N-acetyl-beta-D-glucosaminyl-(1->4)-[nascent hyaluronan] 3-beta-D-glucuronosyltransferase activity|spHAS|seHAS				RHEA:12528|MetaCyc:2.4.1.212-RXN|Reactome:R-HSA-2160851|EC:2.4.1.212									molecular_function											owl:Class	
GO:1900306	biolink:NamedThing	regulation of maltoheptaose transport	Any process that modulates the frequency, rate or extent of maltoheptaose transport.	tmpzr1t_l9r_go_relaxed.owl								tt	2012-04-05T07:58:18Z					biological_process											owl:Class	
GO:0008449	biolink:NamedThing	N-acetylglucosamine-6-sulfatase activity	Catalysis of the hydrolysis of the 6-sulfate group of the N-acetyl-D-glucosamine 6-sulfate units of heparan sulfate and keratan sulfate.	tmpzr1t_l9r_go_relaxed.owl	N-acetylglucosamine 6-sulfate sulfatase activity|glucosamine-6-sulfatase activity|N-acetyl-D-glucosamine-6-sulfate 6-sulfohydrolase activity|N-acetylglucosamine-6-sulphatase activity|2-acetamido-2-deoxy-D-glucose 6-sulfate sulfatase activity|acetylglucosamine 6-sulfatase activity|O,N-disulfate O-sulfohydrolase activity|chondroitinsulfatase				Reactome:R-HSA-2263495|Reactome:R-HSA-1638032|MetaCyc:3.1.6.14-RXN|EC:3.1.6.14									molecular_function											owl:Class	
GO:0008484	biolink:NamedThing	sulfuric ester hydrolase activity	Catalysis of the reaction: RSO-R' + H2O = RSOOH + R'H. This reaction is the hydrolysis of a sulfuric ester bond, an ester formed from sulfuric acid, O=SO(OH)2.	tmpzr1t_l9r_go_relaxed.owl	sulfatase activity|sulphuric ester hydrolase activity				MetaCyc:ARYLSULFAT-RXN|EC:3.1.6.-									molecular_function											owl:Class	
GO:0010440	biolink:NamedThing	stomatal lineage progression	The process in which an unspecialized epidermal cell progresses through a series of divisions that culminate in the production of a stomatal complex.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0048869	biolink:NamedThing	cellular developmental process	A biological process whose specific outcome is the progression of a cell over time from an initial condition to a later condition.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0097720	biolink:NamedThing	calcineurin-mediated signaling	Any intracellular signal transduction in which the signal is passed on within the cell by activation of a transcription factor as a consequence of dephosphorylation by Ca(2+)-activated calcineurin. The process begins with calcium-dependent activation of the phosphatase calcineurin. Calcineurin is a calcium- and calmodulin-dependent serine/threonine protein phosphatase with a conserved function in eukaryotic species from yeast to humans. In yeast and fungi, calcineurin regulates stress signaling and cell cycle, and sporulation and virulence in pathogenic fungi. In metazoans, calcineurin is involved in cell commitment, organogenesis and organ development and immune function of T-lymphocytes. By a conserved mechanism, calcineurin phosphatase activates fungal Crz1 and mammalian NFATc by dephosphorylation and translocation of these transcription factors to the nucleus to regulate gene expression.	tmpzr1t_l9r_go_relaxed.owl	calcineurin signaling|calcineurin-mediated signalling							pr	2016-08-25T15:22:21Z					biological_process											owl:Class	
GO:1903567	biolink:NamedThing	regulation of protein localization to ciliary membrane	Any process that modulates the frequency, rate or extent of protein localization to ciliary membrane.	tmpzr1t_l9r_go_relaxed.owl	regulation of protein localization in ciliary membrane|regulation of protein localisation in ciliary membrane|regulation of protein localisation to ciliary membrane							krc	2014-10-24T21:32:51Z					biological_process											owl:Class	
GO:1903564	biolink:NamedThing	regulation of protein localization to cilium	Any process that modulates the frequency, rate or extent of protein localization to cilium.	tmpzr1t_l9r_go_relaxed.owl								krc	2014-10-24T20:58:11Z					biological_process											owl:Class	
GO:1990266	biolink:NamedThing	neutrophil migration	The movement of a neutrophil within or between different tissues and organs of the body.	tmpzr1t_l9r_go_relaxed.owl								sl	2014-01-10T00:17:47Z					biological_process											owl:Class	
GO:0097530	biolink:NamedThing	granulocyte migration	The movement of a granulocyte within or between different tissues and organs of the body.	tmpzr1t_l9r_go_relaxed.owl								pr	2013-11-11T14:00:44Z					biological_process											owl:Class	
GO:0071943	biolink:NamedThing	Myc-Max complex	A transcription factor complex that consists of a heterodimer of the bHLH-ZIP proteins Myc and Max.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-10-01T11:56:17Z					cellular_component											owl:Class	
GO:0035908	biolink:NamedThing	ventral aorta development	The progression of the ventral aorta over time, from its initial formation to the mature structure. The ventral aorta is a blood vessel in a single-pass circulatory system that carries de-oxygenated blood from the heart to the gills. In a single-pass circulatory system blood passes once through the heart to supply the body once.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-06-24T11:08:49Z					biological_process											owl:Class	
GO:0035904	biolink:NamedThing	aorta development	The progression of the aorta over time, from its initial formation to the mature structure. An aorta is an artery that carries blood from the heart to other parts of the body.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-06-24T11:00:07Z					biological_process											owl:Class	
GO:1900113	biolink:NamedThing	negative regulation of histone H3-K9 trimethylation	Any process that stops, prevents or reduces the frequency, rate or extent of histone H3-K9 trimethylation.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of histone H3-K9 trimethylation|inhibition of histone H3-K9 trimethylation|downregulation of histone H3-K9 trimethylation|down regulation of histone H3-K9 trimethylation							bf	2012-02-21T09:09:54Z					biological_process											owl:Class	
GO:0046277	biolink:NamedThing	methylgallate biosynthetic process	The chemical reactions and pathways resulting in the formation of methylgallate, trihydroxymethylbenzoate, the anion of methylgallic acid.	tmpzr1t_l9r_go_relaxed.owl	methylgallate synthesis|methylgallate biosynthesis|methylgallate formation|methylgallate anabolism													biological_process											owl:Class	
GO:0036176	biolink:NamedThing	response to neutral pH	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a neutral pH (pH close to 7) stimulus. pH is a measure of the acidity or basicity of an aqueous solution.	tmpzr1t_l9r_go_relaxed.owl								bf	2012-03-29T01:38:00Z					biological_process											owl:Class	
GO:0009268	biolink:NamedThing	response to pH	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus. pH is a measure of the acidity or basicity of an aqueous solution.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0005971	biolink:NamedThing	ribonucleoside-diphosphate reductase complex	An enzyme complex composed of 2-4 or more subunits, which usually contains nonheme iron and requires ATP for catalysis. Catalyzes the formation of 2'-deoxyribonucleoside diphosphate from ribonucleoside diphosphate, using either thioredoxin disulfide or glutaredoxin disulfide as an acceptor.	tmpzr1t_l9r_go_relaxed.owl	ribonucleotide reductase complex|RNR complex													cellular_component											owl:Class	
GO:0004668	biolink:NamedThing	protein-arginine deiminase activity	Catalysis of the reaction: protein L-arginine + H2O = protein L-citrulline + NH3. This reaction is calcium-dependent.	tmpzr1t_l9r_go_relaxed.owl	peptidylarginine deiminase activity|protein-L-arginine iminohydrolase activity	https://github.com/geneontology/go-ontology/issues/18666			Reactome:R-HSA-1183128|EC:3.5.3.15|Reactome:R-HSA-3247569|RHEA:18089|MetaCyc:PROTEIN-ARGININE-DEIMINASE-RXN									molecular_function											owl:Class	
GO:0061356	biolink:NamedThing	regulation of Wnt protein secretion	Any process that modulates the frequency, rate or extent of the controlled release of a Wnt protein from a cell.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-10-08T01:09:51Z					biological_process											owl:Class	
GO:0048835	biolink:NamedThing	specification of decreased petal number	Any process that reduces the number of petals produced in a developing flower.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0048834	biolink:NamedThing	specification of petal number	Any process that modulates the number of petals formed in a flower.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0071950	biolink:NamedThing	FADH2 binding	Binding to the reduced form, FADH2, of flavin-adenine dinucleotide, the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes.	tmpzr1t_l9r_go_relaxed.owl	reduced flavine-adenine dinucleotide binding|reduced flavin adenine dinucleotide binding							mah	2010-10-07T12:31:34Z					molecular_function											owl:Class	
GO:0050660	biolink:NamedThing	flavin adenine dinucleotide binding	Binding to FAD, flavin-adenine dinucleotide, the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes, in either the oxidized form, FAD, or the reduced form, FADH2.	tmpzr1t_l9r_go_relaxed.owl	FAD or FADH2 binding|flavine-adenine dinucleotide binding													molecular_function											owl:Class	
GO:0001820	biolink:NamedThing	serotonin secretion	The regulated release of serotonin by a cell. Serotonin (5-hydroxytryptamine, or 5-HT) is a monoamine synthesised in serotonergic neurons in the central nervous system, enterochromaffin cells in the gastrointestinal tract and some immune system cells.	tmpzr1t_l9r_go_relaxed.owl	serotonin release|5-hydroxytryptamine secretion|5-HT secretion													biological_process											owl:Class	
GO:1990622	biolink:NamedThing	CHOP-ATF3 complex	A heterodimeric protein complex that is composed of CHOP (C/EBP homology protein, GADD153) and ATF3 (activating transcription factor 3) subunits.	tmpzr1t_l9r_go_relaxed.owl	ATF3-CHOP complex|CHOP-ATF3 heterodimeric complex|GADD153-ATF3 complex|CHOP-ATF3 heterodimer							bf	2015-01-29T16:43:19Z					cellular_component											owl:Class	
GO:1905935	biolink:NamedThing	positive regulation of cell fate determination	Any process that activates or increases the frequency, rate or extent of cell fate determination.	tmpzr1t_l9r_go_relaxed.owl	upregulation of cell fate determination|activation of cell fate determination|up-regulation of cell fate determination|up regulation of cell fate determination							bhm	2017-02-09T11:25:38Z					biological_process											owl:Class	
GO:0032964	biolink:NamedThing	collagen biosynthetic process	The chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. Collagen is highly enriched in glycine (some regions are 33% glycine) and proline, occurring predominantly as 3-hydroxyproline (about 20%).	tmpzr1t_l9r_go_relaxed.owl	collagen synthesis|collagen formation|collagen biosynthesis|collagen anabolism													biological_process											owl:Class	
GO:0032963	biolink:NamedThing	collagen metabolic process	The chemical reactions and pathways involving collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. Collagen is highly enriched in glycine (some regions are 33% glycine) and proline, occurring predominantly as 3-hydroxyproline (about 20%).	tmpzr1t_l9r_go_relaxed.owl	collagen metabolism													biological_process											owl:Class	
GO:0009969	biolink:NamedThing	xyloglucan biosynthetic process	The chemical reactions and pathways resulting in the formation of xyloglucan, the cross-linking glycan composed of (1->4)-beta-D glucan backbone substituted at regular intervals with beta-D-xylosyl-(1->6) residues, which is present in the primary cell wall of most higher plants.	tmpzr1t_l9r_go_relaxed.owl	xyloglucan synthesis|xyloglucan biosynthesis|xyloglucan formation|xyloglucan anabolism													biological_process											owl:Class	
GO:0048670	biolink:NamedThing	regulation of collateral sprouting	Any process that modulates the frequency, rate or extent of collateral sprouting.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0050770	biolink:NamedThing	regulation of axonogenesis	Any process that modulates the frequency, rate or extent of axonogenesis, the generation of an axon, the long process of a neuron.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0010848	biolink:NamedThing	regulation of chromatin disassembly	Any process that modulates the frequency, rate or extent of chromatin disassembly. Chromatin disassembly is the controlled breakdown of chromatin from a higher order structure into its simpler subcomponents, DNA, histones, and other proteins.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0001672	biolink:NamedThing	regulation of chromatin assembly or disassembly	Any process that modulates the frequency, rate or extent of chromatin assembly or disassembly.	tmpzr1t_l9r_go_relaxed.owl	regulation of chromatin assembly/disassembly													biological_process											owl:Class	
GO:0061360	biolink:NamedThing	optic chiasma development	The developmental process pertaining to the progression of the optic chiasm from its initial formation to the mature structure. The process begins when the pathfinding of the axons of the developing optic nerve cause some axons to cross at the midline of the brain and ends when the axons are mature.	tmpzr1t_l9r_go_relaxed.owl	optic chiasm development							dph	2010-10-13T08:00:29Z					biological_process											owl:Class	
GO:0036450	biolink:NamedThing	polyuridylation-dependent decapping of nuclear-transcribed mRNA	Cleavage of the 5'-cap of a nuclear-transcribed mRNA that has been modified by the enzymatic addition of a sequence of uridylyl residues (polyuridylation) at the 3' end.	tmpzr1t_l9r_go_relaxed.owl	uridylation-dependent decapping of nuclear-transcribed mRNA							bf	2013-11-04T11:37:28Z					biological_process											owl:Class	
GO:0031087	biolink:NamedThing	deadenylation-independent decapping of nuclear-transcribed mRNA	Cleavage of the 5'-cap of a nuclear-transcribed mRNA that is independent of poly(A) tail shortening.	tmpzr1t_l9r_go_relaxed.owl	deadenylylation-independent decapping|deadenylation-independent decapping of nuclear mRNA													biological_process											owl:Class	
GO:0009694	biolink:NamedThing	jasmonic acid metabolic process	The chemical reactions and pathways involving jasmonic acid, a fatty acid derivative with the formula (1R-(1 alpha, 2 beta(Z)))-3-oxo-2-(2-pentenyl)cyclopentaneacetic acid.	tmpzr1t_l9r_go_relaxed.owl	jasmonic acid metabolism													biological_process											owl:Class	
GO:0071939	biolink:NamedThing	vitamin A import	The directed movement of vitamin A into a cell or organelle. Vitamin A is any of several retinoid derivatives of beta-carotene, primarily retinol, retinal, or retinoic acid.	tmpzr1t_l9r_go_relaxed.owl	vitamin A uptake							mah	2010-09-30T04:36:22Z					biological_process											owl:Class	
GO:0071938	biolink:NamedThing	vitamin A transport	The directed movement any form of vitamin A into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Vitamin A is any of several retinoid derivatives of beta-carotene, primarily retinol, retinal, or retinoic acid.	tmpzr1t_l9r_go_relaxed.owl	vitamin A uptake and transport							mah	2010-09-30T04:15:10Z					biological_process											owl:Class	
GO:1901935	biolink:NamedThing	beta-caryophyllene metabolic process	The chemical reactions and pathways involving beta-caryophyllene.	tmpzr1t_l9r_go_relaxed.owl	beta-caryophyllene metabolism							ms	2013-02-18T14:55:06Z					biological_process											owl:Class	
GO:0045843	biolink:NamedThing	negative regulation of striated muscle tissue development	Any process that stops, prevents, or reduces the frequency, rate or extent of striated muscle development.	tmpzr1t_l9r_go_relaxed.owl	downregulation of striated muscle development|inhibition of striated muscle development|down regulation of striated muscle development|down-regulation of striated muscle development													biological_process											owl:Class	
GO:1901862	biolink:NamedThing	negative regulation of muscle tissue development	Any process that stops, prevents or reduces the frequency, rate or extent of muscle tissue development.	tmpzr1t_l9r_go_relaxed.owl	inhibition of muscle tissue development|down regulation of muscle tissue development|down-regulation of muscle tissue development|downregulation of muscle tissue development							yaf	2013-02-01T10:30:52Z					biological_process											owl:Class	
GO:0044080	biolink:NamedThing	modulation by symbiont of host cGMP-mediated signal transduction	Any process in which a symbiont organism modulates the rate, frequency or extent of cGMP-mediated signaling in its host organism. cGMP-mediated signaling is a series of molecular signals in which a cell uses cyclic GMP to convert an extracellular signal into a response.	tmpzr1t_l9r_go_relaxed.owl	modulation by symbiont of host cGMP-mediated signal transduction pathway|modulation of host cGMP-mediated signal transduction by symbiont|modulation by symbiont of host cGMP-mediated signalling|modulation by symbiont of host cGMP-mediated signaling|regulation by symbiont of host cGMP-mediated signal transduction													biological_process											owl:Class	
GO:0052027	biolink:NamedThing	modulation by symbiont of host signal transduction pathway	Any process in which an organism modulates the frequency, rate or extent of the host signal transduction pathways, the cascade of processes by which a signal interacts with a receptor. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	modulation by symbiont of host signal transduction|modulation of signal transduction in other organism involved in symbiotic interaction|regulation by symbiont of host signal transduction pathway|modulation of host signal transduction by symbiont											GO:0052250		biological_process											owl:Class	
GO:0095500	biolink:NamedThing	acetylcholine receptor signaling pathway	The series of molecular signals generated as a consequence of an acetylcholine receptor binding to one of its physiological ligands.	tmpzr1t_l9r_go_relaxed.owl	acetylcholine receptor signalling pathway													biological_process											owl:Class	
GO:0098926	biolink:NamedThing	postsynaptic signal transduction	Signal transduction in which the initial step occurs in a postsynapse.	tmpzr1t_l9r_go_relaxed.owl	postsynaptic signaling pathway					Do not directly annotate. This term is intended for automatically grouping annotations to signal transduction classes extended with has_start_location/occurs_in postsynapse or one of its parts.								biological_process											owl:Class	
GO:0060334	biolink:NamedThing	regulation of interferon-gamma-mediated signaling pathway	Any process that modulates the rate, frequency or extent of the series of molecular events generated as a consequence of interferon-gamma binding to a cell surface receptor.	tmpzr1t_l9r_go_relaxed.owl	regulation of type II IFN-mediated signaling pathway|regulation of interferon-gamma-mediated signalling pathway|regulation of immune interferon signaling pathway|regulation of type II interferon-mediated signaling pathway|regulation of gamma-interferon-mediated signaling pathway													biological_process											owl:Class	
GO:0001959	biolink:NamedThing	regulation of cytokine-mediated signaling pathway	Any process that modulates the frequency, rate or extent of the cytokine mediated signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	regulation of cytokine and chemokine mediated signaling pathway|regulation of cytokine mediated signaling pathway|regulation of cytokine mediated signalling pathway													biological_process											owl:Class	
GO:0001182	biolink:NamedThing	promoter clearance from RNA polymerase I promoter	Any process involved in the transition from the initiation to the elongation phases of transcription by RNA polymerase I, generally including a conformational change from the initiation conformation to the elongation conformation. Promoter clearance often involves breaking contact with transcription factors involved only in the initiation phase and making contacts with elongation specific factors.	tmpzr1t_l9r_go_relaxed.owl								krc	2011-08-15T03:49:28Z					biological_process											owl:Class	
GO:0001109	biolink:NamedThing	promoter clearance during DNA-templated transcription	Any process involved in the transition from the initiation to the elongation phases of transcription by a DNA-dependent RNA polymerase, generally including a conformational change from the initiation conformation to the elongation conformation. Promoter clearance often involves breaking contact with transcription factors involved only in the initiation phase and making contacts with elongation specific factors.	tmpzr1t_l9r_go_relaxed.owl	promoter clearance during DNA-dependent transcription|promoter escape|promoter clearance from bacterial-type RNA polymerase promoter							krc	2010-12-01T02:13:09Z			GO:0001122		biological_process											owl:Class	
GO:0008202	biolink:NamedThing	steroid metabolic process	The chemical reactions and pathways involving steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus.	tmpzr1t_l9r_go_relaxed.owl	steroid metabolism				Wikipedia:Steroid_metabolism									biological_process											owl:Class	
GO:0050105	biolink:NamedThing	L-gulonolactone oxidase activity	Catalysis of the reaction: L-gulono-1,4-lactone + O2 = L-xylo-hex-3-ulonolactone + H2O2.	tmpzr1t_l9r_go_relaxed.owl	L-gulono-1,4-lactone:oxygen 3-oxidoreductase activity|L-gulono-gamma-lactone:O2 oxidoreductase activity|L-gulono-gamma-lactone oxidase activity|GLO activity|L-gulono-gamma-lactone:oxidoreductase activity				RHEA:32363|EC:1.1.3.8|MetaCyc:L-GULONOLACTONE-OXIDASE-RXN									molecular_function											owl:Class	
GO:0072113	biolink:NamedThing	head kidney development	The process whose specific outcome is the progression of the head kidney over time, from its formation to the mature structure. The head kidney is a pronephros that consists of fused bilateral lobes located in the anterior part of the kidney. It is analogous to the mammalian bone marrow and the primary site of definitive hematopoiesis.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-02-22T11:09:38Z					biological_process											owl:Class	
GO:0038100	biolink:NamedThing	nodal binding	Binding to a nodal protein, a member of the transforming growth factor-beta superfamily.	tmpzr1t_l9r_go_relaxed.owl								bf	2012-02-17T11:19:08Z					molecular_function											owl:Class	
GO:0099111	biolink:NamedThing	microtubule-based transport	A microtubule-based process that results in the transport of organelles, other microtubules, or other cellular components.  Examples include motor-driven movement along microtubules and movement driven by polymerization or depolymerization of microtubules.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0006810	biolink:NamedThing	transport	The directed movement of substances (such as macromolecules, small molecules, ions) or cellular components (such as complexes and organelles) into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter, pore or motor protein.	tmpzr1t_l9r_go_relaxed.owl	solute:solute exchange|small molecule transport|single-organism transport					Note that this term should not be used for direct annotation. It should be possible to make a more specific annotation to one of the children of this term, for e.g. to transmembrane transport, to microtubule-based transport or to vesicle-mediated transport.		jl	2012-12-13T16:25:32Z			GO:0015457|GO:0044765|GO:0015460		biological_process											owl:Class	
GO:0080101	biolink:NamedThing	phosphatidyl-N-dimethylethanolamine N-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + phosphatidyl-N-dimethylethanolamine = S-adenosyl-L-homocysteine + phosphatidylcholine.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN4FS-2|RHEA:32739|KEGG_REACTION:R01320|EC:2.1.1.71			dhl	2009-04-23T04:02:41Z					molecular_function											owl:Class	
GO:0042920	biolink:NamedThing	3-hydroxyphenylpropionic acid transmembrane transport	The directed movement of 3-hydroxyphenylpropionic acid across a lipid bilayer, from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	m-hydroxyphenylpropionic acid transport|3-(3-hydroxyphenyl)propionic acid transport|3-hydroxyphenylpropionic acid transport													biological_process											owl:Class	
GO:0015718	biolink:NamedThing	monocarboxylic acid transport	The directed movement of monocarboxylic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0010803	biolink:NamedThing	regulation of tumor necrosis factor-mediated signaling pathway	Any process that modulates the rate or extent of the tumor necrosis factor-mediated signaling pathway. The tumor necrosis factor-mediated signaling pathway is the series of molecular signals generated as a consequence of tumor necrosis factor binding to a cell surface receptor.	tmpzr1t_l9r_go_relaxed.owl	regulation of TNF-mediated signaling pathway|regulation of TNF signaling|regulation of tumor necrosis factor-mediated signalling pathway													biological_process											owl:Class	
GO:2000171	biolink:NamedThing	negative regulation of dendrite development	Any process that stops, prevents, or reduces the frequency, rate or extent of dendrite development.	tmpzr1t_l9r_go_relaxed.owl								rl	2010-10-07T10:53:15Z					biological_process											owl:Class	
GO:0009686	biolink:NamedThing	gibberellin biosynthetic process	The chemical reactions and pathways resulting in the formation of gibberellin. Gibberellins are a class of highly modified terpenes that function as plant growth regulators.	tmpzr1t_l9r_go_relaxed.owl	gibberellic acid synthesis|gibberellic acid biosynthesis|gibberellin biosynthesis|gibberellic acid biosynthetic process|gibberellic acid anabolism|gibberellic acid formation				MetaCyc:PWY-5070|MetaCyc:PWY-5052|MetaCyc:PWY-5035|MetaCyc:PWY-5036									biological_process											owl:Class	
GO:0140131	biolink:NamedThing	positive regulation of lymphocyte chemotaxis	Any process that activates or increases the frequency, rate or extent of lymphocyte chemotaxis.	tmpzr1t_l9r_go_relaxed.owl								pg	2017-11-02T10:26:40Z					biological_process											owl:Class	
GO:1901623	biolink:NamedThing	regulation of lymphocyte chemotaxis	Any process that modulates the frequency, rate or extent of lymphocyte chemotaxis.	tmpzr1t_l9r_go_relaxed.owl								tb	2012-11-13T23:03:23Z					biological_process											owl:Class	
GO:0099041	biolink:NamedThing	vesicle tethering to Golgi	The initial, indirect interaction between a transport vesicle membrane and the membrane of the Golgi. This interaction is mediated by tethering factors (or complexes), which interact with both membranes.  Interaction can occur via direct binding  to membrane phospholipids or membrane proteins, or via binding to vesicle coat proteins. This process is distinct from and prior fusion.	tmpzr1t_l9r_go_relaxed.owl								tb	2013-01-08T15:07:50Z					biological_process											owl:Class	
GO:0099022	biolink:NamedThing	vesicle tethering	The initial, indirect interaction between a vesicle membrane and a membrane to which it is targeted for fusion. This interaction is mediated by tethering factors (or complexes), which interact with both membranes.  Interaction can occur via direct binding  to membrane phospholipids or membrane proteins, or via binding to vesicle coat proteins. This process is distinct from and prior to interaction between factors involved in fusion.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0030736	biolink:NamedThing	phenol O-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + phenol = S-adenosyl-L-homocysteine + anisole + H(+).	tmpzr1t_l9r_go_relaxed.owl	PMT|S-adenosyl-L-methionine:phenol O-methyltransferase activity				KEGG_REACTION:R01239|EC:2.1.1.25|RHEA:14809|MetaCyc:PHENOL-O-METHYLTRANSFERASE-RXN									molecular_function											owl:Class	
GO:0002710	biolink:NamedThing	negative regulation of T cell mediated immunity	Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell mediated immunity.	tmpzr1t_l9r_go_relaxed.owl	inhibition of T cell mediated immunity|negative regulation of T lymphocyte mediated immunity|down-regulation of T cell mediated immunity|down regulation of T cell mediated immunity|negative regulation of T-cell mediated immunity|negative regulation of T-lymphocyte mediated immunity|downregulation of T cell mediated immunity													biological_process											owl:Class	
GO:0097214	biolink:NamedThing	positive regulation of lysosomal membrane permeability	Any process that increases the frequency, rate or extent of the passage or uptake of molecules by the lysosomal membrane.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of lysosome membrane permeability							pr	2012-01-12T10:22:17Z					biological_process											owl:Class	
GO:1905710	biolink:NamedThing	positive regulation of membrane permeability	Any process that activates or increases the frequency, rate or extent of the passage or uptake of molecules by a membrane.	tmpzr1t_l9r_go_relaxed.owl								hbye	2016-11-18T13:10:53Z					biological_process											owl:Class	
GO:0046400	biolink:NamedThing	keto-3-deoxy-D-manno-octulosonic acid metabolic process	The chemical reactions and pathways involving keto-3-deoxy-D-manno-octulosonic acid, an acidic sugar present in lipopolysaccharides of the outer membranes of some Gram-negative bacteria.	tmpzr1t_l9r_go_relaxed.owl	keto-3-deoxy-D-manno-octulosonic acid metabolism|KDO metabolism|ketodeoxyoctanoate metabolic process|KDO metabolic process													biological_process											owl:Class	
GO:0019752	biolink:NamedThing	carboxylic acid metabolic process	The chemical reactions and pathways involving carboxylic acids, any organic acid containing one or more carboxyl (COOH) groups or anions (COO-).	tmpzr1t_l9r_go_relaxed.owl	carboxylic acid metabolism													biological_process											owl:Class	
GO:0015996	biolink:NamedThing	chlorophyll catabolic process	The chemical reactions and pathways resulting in the breakdown of chlorophyll, any compound of magnesium complexed in a porphyrin (tetrapyrrole) ring and which functions as a photosynthetic pigment, into less complex products.	tmpzr1t_l9r_go_relaxed.owl	chlorophyll degradation|chlorophyll breakdown|chlorophyll catabolism													biological_process											owl:Class	
GO:0015994	biolink:NamedThing	chlorophyll metabolic process	The chemical reactions and pathways involving chlorophyll, any compound of magnesium complexed in a porphyrin (tetrapyrrole) ring and which functions as a photosynthetic pigment.	tmpzr1t_l9r_go_relaxed.owl	chlorophyll metabolism													biological_process											owl:Class	
GO:0052187	biolink:NamedThing	modification by host of symbiont cellular component	The process in which an organism effects a change in the structure or function of a symbiont cellular component. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0052183	biolink:NamedThing	modification by host of symbiont structure	The process in which an organism effects a change in an anatomical part or cellular component of the host organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1901661	biolink:NamedThing	quinone metabolic process	The chemical reactions and pathways involving quinone.	tmpzr1t_l9r_go_relaxed.owl	quinone cofactor metabolic process|quinone cofactor metabolism|quinone metabolism							pr	2012-11-20T14:44:39Z			GO:0042375		biological_process											owl:Class	
GO:2000073	biolink:NamedThing	regulation of cytokinesis, site selection	Any process that modulates the frequency, rate or extent of site selection that occurs as part of cytokinesis.	tmpzr1t_l9r_go_relaxed.owl	regulation of site selection involved in cell cycle cytokinesis							tb	2010-08-27T11:15:15Z					biological_process											owl:Class	
GO:0019409	biolink:NamedThing	aerobic respiration, using ammonia as electron donor	The metabolic process in which ammonia (NH3) is oxidized to nitrite (NO2) in the presence of oxygen; enzymatic reactions convert ammonia to hydrazine, and hydrazine to nitrite.	tmpzr1t_l9r_go_relaxed.owl	aerobic ammonia oxidation to nitrite via hydrazine				MetaCyc:AMMOXID-PWY									biological_process											owl:Class	
GO:0009060	biolink:NamedThing	aerobic respiration	The enzymatic release of energy from inorganic and organic compounds (especially carbohydrates and fats) which requires oxygen as the terminal electron acceptor.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:PWY-3781|Wikipedia:Cellular_respiration#Aerobic_respiration									biological_process											owl:Class	
GO:0048377	biolink:NamedThing	lateral mesodermal cell fate specification	The process in which a cell becomes capable of differentiating autonomously into a lateral mesoderm cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.	tmpzr1t_l9r_go_relaxed.owl	lateral mesoderm cell fate specification|lateral plate mesodermal cell fate specification|lateral plate mesoderm cell fate specification													biological_process											owl:Class	
GO:0007501	biolink:NamedThing	mesodermal cell fate specification	The cell fate determination process in which a cell becomes capable of differentiating autonomously into a mesoderm cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.	tmpzr1t_l9r_go_relaxed.owl	mesoderm cell fate specification					Note that this term was 'fate specification in mesoderm'. String of term was changed to correspond to format of sibling terms 'endoderm cell fate specification' and 'ectoderm cell fate specification'.								biological_process											owl:Class	
GO:0005923	biolink:NamedThing	bicellular tight junction	An occluding cell-cell junction that is composed of a branching network of sealing strands that completely encircles the apical end of each cell in an epithelial sheet; the outer leaflets of the two interacting plasma membranes are seen to be tightly apposed where sealing strands are present. Each sealing strand is composed of a long row of transmembrane adhesion proteins embedded in each of the two interacting plasma membranes.	tmpzr1t_l9r_go_relaxed.owl	zonula occludens				NIF_Subcellular:sao1939999134|Wikipedia:Tight_junction									cellular_component											owl:Class	
GO:0070160	biolink:NamedThing	tight junction	A cell-cell junction that seals cells together in an epithelium in a way that prevents even small molecules from leaking from one side of the sheet to the other.	tmpzr1t_l9r_go_relaxed.owl	occluding junction|occluding cell junction				Wikipedia:Tight_junction									cellular_component											owl:Class	
GO:0021708	biolink:NamedThing	Lugaro cell differentiation	The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature Lugaro cell. Differentiation includes the processes involved in commitment of a neuroblast to a Lugaro cell fate. A Lugaro cell is an inhibitory GABAergic interneuron found in the cerebellar cortex.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0097154	biolink:NamedThing	GABAergic neuron differentiation	The process in which a neuroblast acquires the specialized structural and functional features of a GABAergic neuron.	tmpzr1t_l9r_go_relaxed.owl								pr	2011-09-14T09:39:11Z					biological_process											owl:Class	
GO:0051639	biolink:NamedThing	actin filament network formation	The assembly of a network of actin filaments; actin filaments on different axes and with differing orientations are crosslinked together to form a mesh of filaments.	tmpzr1t_l9r_go_relaxed.owl	actin gel formation|actin gel biosynthesis													biological_process											owl:Class	
GO:0007015	biolink:NamedThing	actin filament organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments. Includes processes that control the spatial distribution of actin filaments, such as organizing filaments into meshworks, bundles, or other structures, as by cross-linking.	tmpzr1t_l9r_go_relaxed.owl	regulation of actin filament localization|actin filament organisation													biological_process											owl:Class	
GO:1904155	biolink:NamedThing	DN2 thymocyte differentiation	The process in which a relatively unspecialized cell acquires the specialized features of a DN2 thymocyte. A DN2 thymocyte is a CD4-,CD8- thymocyte that is also CD44+,CD25-.	tmpzr1t_l9r_go_relaxed.owl								dph	2015-04-15T12:52:53Z					biological_process											owl:Class	
GO:0033077	biolink:NamedThing	T cell differentiation in thymus	The process in which a precursor cell type acquires the specialized features of a T cell via a differentiation pathway dependent upon transit through the thymus.	tmpzr1t_l9r_go_relaxed.owl	thymic T cell differentiation|T cell development in thymus|thymocyte differentiation|thymocyte cell differentiation					Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.								biological_process											owl:Class	
GO:0022804	biolink:NamedThing	active transmembrane transporter activity	Enables the transfer of a specific substance or related group of substances from one side of a membrane to the other, up the solute's concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction.	tmpzr1t_l9r_go_relaxed.owl	pump activity|carrier activity|permease activity|active carrier activity													molecular_function											owl:Class	
GO:0071883	biolink:NamedThing	MAPK-activating adrenergic receptor signaling pathway	The series of molecular signals generated as a consequence of an adrenergic receptor binding to its physiological ligand and leading to the activation of a MAP kinase cascade.	tmpzr1t_l9r_go_relaxed.owl	activation of MAP kinase activity by adrenergic receptor signaling pathway|activation of MAP kinase activity by adrenergic receptor signalling pathway|activation of MAPK activity by adrenergic receptor signalling pathway|activation of MAPK activity by adrenergic receptor signaling pathway	https://github.com/geneontology/go-ontology/issues/21544						mah	2010-09-13T04:34:47Z					biological_process											owl:Class	
GO:0071875	biolink:NamedThing	adrenergic receptor signaling pathway	A series of molecular signals generated as a consequence of an adrenergic receptor binding to one of its physiological ligands.	tmpzr1t_l9r_go_relaxed.owl	adrenergic receptor signalling pathway|adrenoceptor signaling pathway							mah	2010-09-13T03:44:44Z					biological_process											owl:Class	
GO:0102783	biolink:NamedThing	beta-carotene oxygenase activity	Catalysis of the reaction: beta-carotene + 2 O2 = 2 beta-ionone + 4,9-dimethyldodeca-2,4,6,8,10-pentaenedial.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-7883									molecular_function											owl:Class	
GO:0016119	biolink:NamedThing	carotene metabolic process	The chemical reactions and pathways involving carotenes, hydrocarbon carotenoids.	tmpzr1t_l9r_go_relaxed.owl	carotene metabolism													biological_process											owl:Class	
GO:0031025	biolink:NamedThing	equatorial microtubule organizing center disassembly	The process in which the equatorial microtubule organizing center is disassembled at the end of mitosis.	tmpzr1t_l9r_go_relaxed.owl	equatorial microtubule organising center disassembly													biological_process											owl:Class	
GO:0060393	biolink:NamedThing	regulation of pathway-restricted SMAD protein phosphorylation	Any process that modulates the rate, frequency or extent of pathway-restricted SMAD protein phosphorylation. Pathway-restricted SMAD proteins and common-partner SMAD proteins are involved in the transforming growth factor beta receptor signaling pathways.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0030612	biolink:NamedThing	arsenate reductase (thioredoxin) activity	Catalysis of the reaction: arsenate + thioredoxin = arsenite + thioredoxin disulfide. Thioredoxin disulfide is also known as oxidized thioredoxin.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-10737									molecular_function											owl:Class	
GO:0030611	biolink:NamedThing	arsenate reductase activity	Catalysis of the interconversion of arsenate and arsenite.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0004521	biolink:NamedThing	endoribonuclease activity	Catalysis of the hydrolysis of ester linkages within ribonucleic acid by creating internal breaks.	tmpzr1t_l9r_go_relaxed.owl	endonuclease G activity				Reactome:R-HSA-426520|Reactome:R-HSA-9009936|Reactome:R-HSA-425923|Reactome:R-HSA-9023912|Reactome:R-HSA-927836|Reactome:R-HSA-6814555|Reactome:R-HSA-9023909|Reactome:R-HSA-5601910|Reactome:R-HSA-5601887|Reactome:R-HSA-6791223|Reactome:R-HSA-9009941									molecular_function											owl:Class	
GO:1904512	biolink:NamedThing	regulation of initiation of premeiotic DNA replication	Any process that modulates the frequency, rate or extent of initiation of premeiotic DNA replication.	tmpzr1t_l9r_go_relaxed.owl	regulation of initiation of premeiotic DNA synthesis|regulation of initiation of meiotic DNA synthesis|regulation of premeiotic DNA replication initiation|regulation of meiotic DNA replication initiation							mah	2015-07-28T12:59:17Z					biological_process											owl:Class	
GO:1904982	biolink:NamedThing	sucrose transmembrane transport	The process in which sucrose is transported across a membrane.	tmpzr1t_l9r_go_relaxed.owl								vw	2016-02-28T21:16:51Z					biological_process											owl:Class	
GO:0090190	biolink:NamedThing	positive regulation of branching involved in ureteric bud morphogenesis	Any process that increases the rate, frequency or extent of branching involved in ureteric bud morphogenesis, the process in which the branching structure of the ureteric bud is generated and organized. The ureteric bud is an epithelial tube that grows out from the metanephric duct. The bud elongates and branches to give rise to the ureter and kidney collecting tubules.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-12-18T11:11:17Z					biological_process											owl:Class	
GO:1902219	biolink:NamedThing	negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress	Any process that stops, prevents or reduces the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to osmotic stress.	tmpzr1t_l9r_go_relaxed.owl	downregulation of intrinsic apoptotic signaling pathway in response to osmotic stress|down-regulation of intrinsic apoptotic signaling pathway in response to osmotic stress|down regulation of intrinsic apoptotic signaling pathway in response to osmotic stress|inhibition of intrinsic apoptotic signaling pathway in response to osmotic stress							rl	2013-06-13T10:19:12Z					biological_process											owl:Class	
GO:1904230	biolink:NamedThing	negative regulation of succinate dehydrogenase activity	Any process that stops, prevents or reduces the frequency, rate or extent of succinate dehydrogenase activity.	tmpzr1t_l9r_go_relaxed.owl	inhibition of fumarate dehydrogenase activity|down-regulation of succinate dehydrogenase activity|downregulation of fumaric hydrogenase activity|down regulation of fumarate dehydrogenase activity|downregulation of succinic acid dehydrogenase activity|downregulation of succinate:(acceptor) oxidoreductase activity|down-regulation of succinate:(acceptor) oxidoreductase activity|down regulation of succinate:(acceptor) oxidoreductase activity|downregulation of succinate:acceptor oxidoreductase activity|downregulation of succinyl dehydrogenase activity|down-regulation of succinyl dehydrogenase activity|inhibition of succinate oxidoreductase activity|down regulation of succinyl dehydrogenase activity|downregulation of succinodehydrogenase activity|down regulation of fumarate reductase activity|negative regulation of succinodehydrogenase activity|down-regulation of succinate:acceptor oxidoreductase activity|negative regulation of fumaric hydrogenase activity|negative regulation of succinate:(acceptor) oxidoreductase activity|inhibition of succinic acid dehydrogenase activity|down-regulation of fumarate reductase activity|negative regulation of fumarate reductase activity|down regulation of succinate dehydrogenase activity|down-regulation of fumaric hydrogenase activity|inhibition of fumarate reductase activity|downregulation of fumarate dehydrogenase activity|inhibition of succinyl dehydrogenase activity|down regulation of succinate oxidoreductase activity|down regulation of succinodehydrogenase activity|downregulation of succinate oxidoreductase activity|downregulation of succinate dehydrogenase activity|inhibition of succinate:acceptor oxidoreductase activity|down regulation of succinic acid dehydrogenase activity|down-regulation of fumarate dehydrogenase activity|down-regulation of succinic acid dehydrogenase activity|negative regulation of succinate oxidoreductase activity|negative regulation of fumarate dehydrogenase activity|down-regulation of succinodehydrogenase activity|down regulation of succinate:acceptor oxidoreductase activity|inhibition of succinate:(acceptor) oxidoreductase activity|negative regulation of succinic acid dehydrogenase activity|inhibition of fumaric hydrogenase activity|down regulation of fumaric hydrogenase activity|inhibition of succinodehydrogenase activity|down-regulation of succinate oxidoreductase activity|negative regulation of succinyl dehydrogenase activity|negative regulation of succinate:acceptor oxidoreductase activity|downregulation of fumarate reductase activity|inhibition of succinate dehydrogenase activity							rl	2015-05-15T09:51:14Z					biological_process											owl:Class	
GO:1903070	biolink:NamedThing	negative regulation of ER-associated ubiquitin-dependent protein catabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of ER-associated ubiquitin-dependent protein catabolic process.	tmpzr1t_l9r_go_relaxed.owl	inhibition of ER-associated protein degradation|inhibition of endoplasmic reticulum-associated protein catabolism|down-regulation of ER-associated protein catabolic process|negative regulation of ERAD|negative regulation of endoplasmic reticulum-associated protein catabolism|down-regulation of endoplasmic reticulum-associated protein catabolic process|negative regulation of ER-associated protein breakdown|downregulation of ER-associated ubiquitin-dependent protein catabolic process|inhibition of ER-associated protein catabolism|down regulation of ER-associated protein breakdown|inhibition of ERAD|down-regulation of ER-associated protein catabolism|down regulation of ER-associated ubiquitin-dependent protein catabolic process|downregulation of ER-associated protein catabolic process|down-regulation of endoplasmic reticulum-associated protein catabolism|down-regulation of ER-associated ubiquitin-dependent protein catabolic process|down-regulation of ERAD|down regulation of endoplasmic reticulum-associated protein catabolic process|downregulation of ER-associated protein breakdown|down regulation of endoplasmic reticulum-associated protein catabolism|down regulation of ER-associated protein catabolism|down-regulation of ER-associated protein breakdown|down regulation of ER-associated protein catabolic process|down regulation of ERAD|negative regulation of endoplasmic reticulum-associated protein catabolic process|negative regulation of ER-associated protein degradation|inhibition of ER-associated ubiquitin-dependent protein catabolic process|downregulation of ERAD|inhibition of ER-associated protein breakdown|down-regulation of ER-associated protein degradation|negative regulation of ER-associated protein catabolism|negative regulation of ER-associated protein catabolic process|inhibition of ER-associated protein catabolic process|down regulation of ER-associated protein degradation|downregulation of ER-associated protein catabolism|downregulation of endoplasmic reticulum-associated protein catabolism|inhibition of endoplasmic reticulum-associated protein catabolic process|downregulation of endoplasmic reticulum-associated protein catabolic process|downregulation of ER-associated protein degradation							rph	2014-05-28T17:53:53Z					biological_process											owl:Class	
GO:1904293	biolink:NamedThing	negative regulation of ERAD pathway	Any process that stops, prevents or reduces the frequency, rate or extent of ERAD pathway.	tmpzr1t_l9r_go_relaxed.owl	downregulation of ER-associated degradation pathway|down-regulation of endoplasmic reticulum-associated degradation|negative regulation of endoplasmic reticulum-associated degradation|down-regulation of ERAD pathway|down regulation of endoplasmic reticulum-associated protein degradation pathway|downregulation of endoplasmic reticulum-associated degradation|down-regulation of ER-associated degradation pathway|down regulation of ER-associated degradation pathway|inhibition of ERAD pathway|down regulation of ERAD pathway|down-regulation of endoplasmic reticulum-associated protein degradation pathway|downregulation of ERAD pathway|inhibition of endoplasmic reticulum-associated protein degradation pathway|down regulation of endoplasmic reticulum-associated degradation|negative regulation of endoplasmic reticulum-associated protein degradation pathway|downregulation of endoplasmic reticulum-associated protein degradation pathway|negative regulation of ER-associated degradation pathway|inhibition of ER-associated degradation pathway|inhibition of endoplasmic reticulum-associated degradation							bf	2015-06-09T14:44:33Z					biological_process											owl:Class	
GO:0019809	biolink:NamedThing	spermidine binding	Binding to spermidine, N-(3-aminopropyl)-1,4-diaminobutane.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1904161	biolink:NamedThing	DNA synthesis involved in UV-damage excision repair	Any DNA synthesis that is involved in UV-damage excision repair.	tmpzr1t_l9r_go_relaxed.owl	mitotic DNA repair synthesis involved in UV-damaged DNA endonuclease-dependent excision repair|DNA synthesis during UV-damaged DNA endonuclease-dependent excision repair|DNA synthesis involved in UVER|mitotic DNA repair synthesis involved in UV-damage excision repair|DNA synthesis involved in UV-damaged DNA endonuclease-dependent excision repair|mitotic DNA repair synthesis involved in UVER|DNA synthesis during UVER|DNA synthesis involved in UVDE-dependent excision repair|mitotic DNA repair synthesis involved in UVDE-dependent excision repair|DNA synthesis during UV-damage excision repair|DNA synthesis involved in AER|DNA synthesis involved in alternative excision repair|DNA synthesis during UVDE-dependent excision repair							mah	2015-04-21T14:53:12Z					biological_process											owl:Class	
GO:0000731	biolink:NamedThing	DNA synthesis involved in DNA repair	Synthesis of DNA that proceeds from the broken 3' single-strand DNA end and uses the homologous intact duplex as the template.	tmpzr1t_l9r_go_relaxed.owl	DNA repair synthesis|mitotic DNA repair synthesis|DNA synthesis during DNA repair													biological_process											owl:Class	
GO:0044862	biolink:NamedThing	protein transport out of plasma membrane raft	The directed movement of a protein out of a plasma membrane raft.	tmpzr1t_l9r_go_relaxed.owl								jl	2014-07-23T16:32:56Z					biological_process											owl:Class	
GO:0045651	biolink:NamedThing	positive regulation of macrophage differentiation	Any process that activates or increases the frequency, rate or extent of macrophage differentiation.	tmpzr1t_l9r_go_relaxed.owl	upregulation of macrophage differentiation|activation of macrophage differentiation|up-regulation of macrophage differentiation|stimulation of macrophage differentiation|up regulation of macrophage differentiation													biological_process											owl:Class	
GO:0045649	biolink:NamedThing	regulation of macrophage differentiation	Any process that modulates the frequency, rate or extent of macrophage differentiation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1901876	biolink:NamedThing	regulation of calcium ion binding	Any process that modulates the frequency, rate or extent of calcium ion binding.	tmpzr1t_l9r_go_relaxed.owl	regulation of calcium ion storage activity							rl	2013-02-06T12:38:12Z					biological_process											owl:Class	
GO:0010265	biolink:NamedThing	SCF complex assembly	The aggregation, arrangement and bonding together of a set of components to form the SKP1-Cullin/Cdc53-F-box protein ubiquitin ligase (SCF) complex.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0003850	biolink:NamedThing	2-deoxyglucose-6-phosphatase activity	Catalysis of the reaction: 2-deoxy-D-glucose-6-phosphate + H2O = 2-deoxy-D-glucose + phosphate.	tmpzr1t_l9r_go_relaxed.owl	2-deoxyglucose-6-phosphate phosphatase activity|2-deoxy-D-glucose-6-phosphate phosphohydrolase activity				MetaCyc:3.1.3.68-RXN|KEGG_REACTION:R02587|EC:3.1.3.68|RHEA:22236									molecular_function											owl:Class	
GO:0060387	biolink:NamedThing	fertilization envelope	A structure that lies outside the plasma membrane and surrounds the egg. The fertilization envelope forms from the vitelline membrane after fertilization as a result of cortical granule release.	tmpzr1t_l9r_go_relaxed.owl	fertilization membrane													cellular_component											owl:Class	
GO:0035805	biolink:NamedThing	egg coat	A specialized extracellular matrix that surrounds the plasma membrane of the ovum of animals. The egg coat provides structural support and can play an essential role in oogenesis, fertilization and early development.	tmpzr1t_l9r_go_relaxed.owl	zona pellucida|vitelline membrane							bf	2011-04-19T02:07:23Z					cellular_component											owl:Class	
GO:0035120	biolink:NamedThing	post-embryonic appendage morphogenesis	The process, occurring after embryonic development, by which the anatomical structures of an appendage are generated and organized. An appendage is an organ or part that is attached to the trunk of an organism, such as a limb or a branch.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0090646	biolink:NamedThing	mitochondrial tRNA processing	The process in which a pre-tRNA molecule is converted to a mature tRNA, ready for addition of an aminoacyl group,  in the mitochondrion.	tmpzr1t_l9r_go_relaxed.owl								tb	2015-06-12T15:57:13Z					biological_process											owl:Class	
GO:0008033	biolink:NamedThing	tRNA processing	The process in which a pre-tRNA molecule is converted to a mature tRNA, ready for addition of an aminoacyl group.	tmpzr1t_l9r_go_relaxed.owl	tRNA maturation													biological_process											owl:Class	
GO:1900723	biolink:NamedThing	negative regulation of protein adenylylation	Any process that stops, prevents or reduces the frequency, rate or extent of protein adenylylation.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of protein adenylation|down-regulation of protein adenylylation|downregulation of protein AMPylation|down regulation of protein adenylylation|down-regulation of protein AMPylation|inhibition of protein adenylation|downregulation of protein adenylylation|negative regulation of protein AMPylation|downregulation of protein amino acid adenylylation|negative regulation of protein amino acid adenylylation|down regulation of protein adenylation|down regulation of protein amino acid adenylylation|downregulation of protein adenylation|negative regulation of protein adenylation|inhibition of protein AMPylation|inhibition of protein amino acid adenylylation|down regulation of protein AMPylation|inhibition of protein adenylylation|down-regulation of protein amino acid adenylylation							jl	2012-05-24T03:16:06Z					biological_process											owl:Class	
GO:0048183	biolink:NamedThing	activin AB complex	A nonsteroidal regulator, composed of two covalently linked inhibin beta subunits (sometimes known as activin beta or activin/inhibin beta), inhibin beta-A and inhibin beta-B.	tmpzr1t_l9r_go_relaxed.owl	inhibin beta-B|inhibin beta-A					Note that the actions of the activin complex are the opposite of those of the inhibin complex, which is a dimer of an inhibin beta-A or inhibin beta-B subunit and a inhibin alpha subunit. See 'inhibin complex ; GO:0043511'.								cellular_component											owl:Class	
GO:0048180	biolink:NamedThing	activin complex	A nonsteroidal regulator, composed of two covalently linked inhibin beta subunits, inhibin beta-A and inhibin beta-B (sometimes known as activin beta or activin/inhibin beta). There are three forms of activin complex, activin A, which is composed of 2 inhibin beta-A subunits, activin B, which is composed of 2 inhibin beta-B subunits, and activin AB, which is composed of an inhibin beta-A and an inhibin beta-B subunit.	tmpzr1t_l9r_go_relaxed.owl						Note that the actions of the activin complex are the opposite of those of the inhibin complex, which is a dimer of an inhibin beta-A or inhibin beta-B subunit and a inhibin alpha subunit. See 'inhibin complex ; GO:0043511'.								cellular_component											owl:Class	
GO:0006741	biolink:NamedThing	NADP biosynthetic process	The chemical reactions and pathways resulting in the formation of nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions; biosynthesis may be of either the oxidized form, NADP, or the reduced form, NADPH.	tmpzr1t_l9r_go_relaxed.owl	NADPH biosynthesis|NADPH biosynthetic process|NADP (oxidized) biosynthetic process|oxidized nicotinamide adenine dinucleotide phosphate biosynthetic process|oxidized NADP biosynthesis|NADP (reduced) biosynthesis|NADP synthesis|reduced NADP biosynthetic process|oxidized NADP biosynthetic process|NADP (reduced) biosynthetic process|reduced nicotinamide adenine dinucleotide phosphate biosynthetic process|nicotinamide adenine dinucleotide phosphate biosynthesis|NADP biosynthesis|reduced nicotinamide adenine dinucleotide phosphate biosynthesis|NADP formation|NADP anabolism|oxidized nicotinamide adenine dinucleotide phosphate biosynthesis|reduced NADP biosynthesis|nicotinamide adenine dinucleotide phosphate biosynthetic process|NADP (oxidized) biosynthesis													biological_process											owl:Class	
GO:0006739	biolink:NamedThing	NADP metabolic process	The chemical reactions and pathways involving nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions; metabolism may be of either the oxidized form, NADP, or the reduced form, NADPH.	tmpzr1t_l9r_go_relaxed.owl	nicotinamide adenine dinucleotide phosphate metabolic process|oxidized nicotinamide adenine dinucleotide phosphate metabolic process|NADP (reduced) metabolic process|nicotinamide adenine dinucleotide phosphate metabolism|reduced nicotinamide adenine dinucleotide phosphate metabolism|NADPH metabolic process|oxidized nicotinamide adenine dinucleotide phosphate metabolism|NADP (reduced) metabolism|reduced NADP metabolism|reduced nicotinamide adenine dinucleotide phosphate metabolic process|reduced NADP metabolic process|NAD phosphorylation and dephosphorylation|NADP (oxidized) metabolic process|NADPH metabolism|NADP (oxidized) metabolism|oxidized NADP metabolism|oxidized NADP metabolic process|NADP metabolism													biological_process											owl:Class	
GO:0072380	biolink:NamedThing	TRC complex	A protein complex found in yeast that contains GET4, MDY2 (GET5), SGT2, and at least two heat shock proteins, HSP104 and YBR137W. The TRC complex transfers tail-anchored (TA) proteins to GET3 for targeting to the endoplasmic reticulum membrane.	tmpzr1t_l9r_go_relaxed.owl	TMD recognition complex|GET4-GET5 transmembrane domain recognition complex	https://github.com/geneontology/go-ontology/issues/20889						mah	2010-11-24T02:43:41Z					cellular_component											owl:Class	
GO:0072379	biolink:NamedThing	ER membrane insertion complex	A protein complex that is involved in the post-translational delivery of tail-anchored (TA) membrane proteins to the endoplasmic reticulum. TA membrane proteins, also called type II transmembrane proteins, contain a single C-terminal transmembrane region. Some ER membrane insertion complex subunits are conserved between different species such as mammals and budding yeast.	tmpzr1t_l9r_go_relaxed.owl	endoplasmic reticulum membrane insertion complex							mah	2010-11-24T02:07:09Z					cellular_component											owl:Class	
GO:0034438	biolink:NamedThing	lipoprotein amino acid oxidation	The modification of a lipoprotein by oxidation of one or more amino acids in the protein.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0018158	biolink:NamedThing	protein oxidation	The modification of a protein amino acid by oxidation.	tmpzr1t_l9r_go_relaxed.owl	protein amino acid oxidation													biological_process											owl:Class	
GO:2001130	biolink:NamedThing	methane biosynthetic process from trimethylamine	The chemical reactions and pathways resulting in the formation of a methane from a trimethylamine.	tmpzr1t_l9r_go_relaxed.owl								jl	2011-10-13T10:28:03Z					biological_process											owl:Class	
GO:0009308	biolink:NamedThing	amine metabolic process	The chemical reactions and pathways involving any organic compound that is weakly basic in character and contains an amino or a substituted amino group. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom.	tmpzr1t_l9r_go_relaxed.owl	amine metabolism													biological_process											owl:Class	
GO:0072100	biolink:NamedThing	specification of ureteric bud anterior/posterior symmetry	The establishment of the ureteric bud such that there is a similar arrangement in form and relationship of parts along its anterior/posterior axis.	tmpzr1t_l9r_go_relaxed.owl	specification of ureteric bud anterior/posterior asymmetry							mah	2010-02-10T02:18:16Z					biological_process											owl:Class	
GO:0009799	biolink:NamedThing	specification of symmetry	The establishment of an organism's body plan or part of an organism such that a similar arrangement in form and relationship of parts around a common axis, or around each side of a plane is created.	tmpzr1t_l9r_go_relaxed.owl	determination of symmetry													biological_process											owl:Class	
GO:0031542	biolink:NamedThing	positive regulation of anthocyanin biosynthetic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of anthocyanins.	tmpzr1t_l9r_go_relaxed.owl	up regulation of anthocyanin biosynthetic process|up-regulation of anthocyanin biosynthetic process|upregulation of anthocyanin biosynthetic process|positive regulation of anthocyanin anabolism|positive regulation of anthocyanin biosynthesis|stimulation of anthocyanin biosynthetic process|positive regulation of anthocyanin formation|positive regulation of anthocyanin synthesis|activation of anthocyanin biosynthetic process													biological_process											owl:Class	
GO:0009963	biolink:NamedThing	positive regulation of flavonoid biosynthetic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of flavonoids.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of flavonoid biosynthetic process|positive regulation of flavonoid biosynthesis|upregulation of flavonoid biosynthetic process|stimulation of flavonoid biosynthetic process|activation of flavonoid biosynthetic process|positive regulation of flavonoid anabolism|up regulation of flavonoid biosynthetic process|positive regulation of flavonoid formation|positive regulation of flavonoid synthesis													biological_process											owl:Class	
GO:1902030	biolink:NamedThing	negative regulation of histone H3-K18 acetylation	Any process that stops, prevents or reduces the frequency, rate or extent of histone H3-K18 acetylation.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of histone H3-K18 acetylation|negative regulation of histone H3K18 acetylation|down-regulation of histone H3K18 acetylation|downregulation of histone H3-K18 acetylation|inhibition of histone H3 acetylation at K18|down-regulation of histone H3 acetylation at K18|downregulation of histone H3 acetylation at K18|down regulation of histone H3 acetylation at K18|down regulation of histone H3-K18 acetylation|negative regulation of histone H3 acetylation at K18|inhibition of histone H3-K18 acetylation|inhibition of histone H3K18 acetylation|down regulation of histone H3K18 acetylation|downregulation of histone H3K18 acetylation							jl	2013-03-28T20:19:39Z					biological_process											owl:Class	
GO:1902028	biolink:NamedThing	regulation of histone H3-K18 acetylation	Any process that modulates the frequency, rate or extent of histone H3-K18 acetylation.	tmpzr1t_l9r_go_relaxed.owl	regulation of histone H3 acetylation at K18|regulation of histone H3K18 acetylation							jl	2013-03-28T20:17:39Z					biological_process											owl:Class	
GO:1902691	biolink:NamedThing	respiratory basal cell differentiation	The process in which a relatively unspecialized cell acquires the specialized features of a respiratory basal cell.	tmpzr1t_l9r_go_relaxed.owl	airway basal cell differentiation					Changes in the lineage choice of ABCs or their undifferentiated daughters might contribute to the mucous cell hyperplasia, metaplasia or squamous metaplasia seen in many respiratory disorders		cjm	2014-02-13T23:41:24Z					biological_process											owl:Class	
GO:0030855	biolink:NamedThing	epithelial cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of an epithelial cell, any of the cells making up an epithelium.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0080098	biolink:NamedThing	L-tyrosine:pyruvate aminotransferase activity	Catalysis of the reaction: L-tyrosine + pyruvate = (4-hydroxyphenyl)pyruvate + L-alanine.	tmpzr1t_l9r_go_relaxed.owl					EC:2.6.1.58|MetaCyc:RXN3O-4157			dhl	2009-04-23T03:47:53Z					molecular_function											owl:Class	
GO:0071351	biolink:NamedThing	cellular response to interleukin-18	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-18 stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to IL-18							mah	2009-12-11T02:50:03Z					biological_process											owl:Class	
GO:0070673	biolink:NamedThing	response to interleukin-18	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-18 stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to IL-18							mah	2009-05-29T10:03:52Z					biological_process											owl:Class	
GO:1990605	biolink:NamedThing	GU repeat RNA binding	Binding to an RNA molecule containing GU repeats.	tmpzr1t_l9r_go_relaxed.owl								al	2015-01-13T18:18:01Z					molecular_function											owl:Class	
GO:1905401	biolink:NamedThing	positive regulation of activated CD4-positive, alpha-beta T cell apoptotic process	Any process that activates or increases the frequency, rate or extent of activated CD4-positive, alpha-beta T cell apoptotic process.	tmpzr1t_l9r_go_relaxed.owl	upregulation of activated CD4-positive, alpha-beta T lymphocyte apoptotic process|up regulation of activated CD4-positive, alpha-beta T cell apoptotic process|up regulation of activated CD4-positive, alpha-beta T-lymphocyte apoptosis|upregulation of activated CD4-positive, alpha-beta T lymphocyte apoptosis|up-regulation of activated CD4-positive, alpha-beta T-lymphocyte apoptosis|upregulation of activated CD4-positive, alpha-beta T cell apoptotic process|up regulation of activated CD4-positive, alpha-beta T-lymphocyte apoptotic process|up regulation of activated CD4-positive, alpha-beta T cell apoptosis|up-regulation of activated CD4-positive, alpha-beta T lymphocyte apoptosis|up-regulation of activated CD4-positive, alpha-beta T-cell apoptosis|upregulation of activated CD4-positive, alpha-beta T cell apoptosis|activation of activated CD4-positive, alpha-beta T-lymphocyte apoptotic process|positive regulation of activated CD4-positive, alpha-beta T-lymphocyte apoptotic process|activation of activated CD4-positive, alpha-beta T-cell apoptotic process|upregulation of activated CD4-positive, alpha-beta T-cell apoptotic process|positive regulation of activated CD4-positive, alpha-beta T-cell apoptosis|up regulation of activated CD4-positive, alpha-beta T-cell apoptosis|positive regulation of activated CD4-positive, alpha-beta T-lymphocyte apoptosis|activation of activated CD4-positive, alpha-beta T-cell apoptosis|activation of activated CD4-positive, alpha-beta T lymphocyte apoptosis|positive regulation of activated CD4-positive, alpha-beta T-cell apoptotic process|upregulation of activated CD4-positive, alpha-beta T-lymphocyte apoptotic process|up-regulation of activated CD4-positive, alpha-beta T-cell apoptotic process|positive regulation of activated CD4-positive, alpha-beta T lymphocyte apoptosis|up regulation of activated CD4-positive, alpha-beta T-cell apoptotic process|up-regulation of activated CD4-positive, alpha-beta T-lymphocyte apoptotic process|up-regulation of activated CD4-positive, alpha-beta T lymphocyte apoptotic process|activation of activated CD4-positive, alpha-beta T cell apoptosis|up-regulation of activated CD4-positive, alpha-beta T cell apoptosis|up regulation of activated CD4-positive, alpha-beta T lymphocyte apoptotic process|positive regulation of activated CD4-positive, alpha-beta T cell apoptosis|activation of activated CD4-positive, alpha-beta T-lymphocyte apoptosis|upregulation of activated CD4-positive, alpha-beta T-cell apoptosis|upregulation of activated CD4-positive, alpha-beta T-lymphocyte apoptosis|activation of activated CD4-positive, alpha-beta T cell apoptotic process|positive regulation of activated CD4-positive, alpha-beta T lymphocyte apoptotic process|activation of activated CD4-positive, alpha-beta T lymphocyte apoptotic process|up-regulation of activated CD4-positive, alpha-beta T cell apoptotic process|up regulation of activated CD4-positive, alpha-beta T lymphocyte apoptosis							pga	2016-08-25T09:10:00Z					biological_process											owl:Class	
GO:0009181	biolink:NamedThing	purine ribonucleoside diphosphate catabolic process	The chemical reactions and pathways resulting in the breakdown of purine ribonucleoside diphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with diphosphate on the sugar.	tmpzr1t_l9r_go_relaxed.owl	purine ribonucleoside diphosphate catabolism|purine ribonucleoside diphosphate degradation|purine ribonucleoside diphosphate breakdown													biological_process											owl:Class	
GO:0009137	biolink:NamedThing	purine nucleoside diphosphate catabolic process	The chemical reactions and pathways resulting in the breakdown of purine nucleoside diphosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with diphosphate on the sugar.	tmpzr1t_l9r_go_relaxed.owl	purine nucleoside diphosphate degradation|purine nucleoside diphosphate breakdown|purine nucleoside diphosphate catabolism													biological_process											owl:Class	
GO:0070953	biolink:NamedThing	regulation of neutrophil mediated killing of fungus	Any process that modulates the rate, frequency or extent of neutrophil mediated killing of a fungal cell, the directed killing of a fungal cell by a neutrophil.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-10-01T02:14:36Z					biological_process											owl:Class	
GO:1900150	biolink:NamedThing	regulation of defense response to fungus	Any process that modulates the frequency, rate or extent of defense response to fungus.	tmpzr1t_l9r_go_relaxed.owl	regulation of resistance response to pathogenic fungus|regulation of defense response to fungus, incompatible interaction|regulation of defense response to fungi, incompatible interaction|regulation of response to pathogenic fungus (incompatible interaction)|regulation of defence response to fungi|regulation of defense response to fungi|regulation of resistance response to pathogenic fungi|regulation of defence response to fungus							dhl	2012-03-06T10:00:16Z			GO:2000072		biological_process											owl:Class	
GO:0001675	biolink:NamedThing	acrosome assembly	The formation of the acrosome from the spermatid Golgi.	tmpzr1t_l9r_go_relaxed.owl	acrosome formation													biological_process											owl:Class	
GO:0009236	biolink:NamedThing	cobalamin biosynthetic process	The chemical reactions and pathways resulting in the formation of cobalamin (vitamin B12), a water-soluble vitamin characterized by possession of a corrin nucleus containing a cobalt atom.	tmpzr1t_l9r_go_relaxed.owl	cobalamin biosynthesis|cobalamin synthesis|vitamin B12 biosynthesis|cobalamin formation|cobalamin anabolism|vitamin B12 biosynthetic process													biological_process											owl:Class	
GO:0018182	biolink:NamedThing	protein-heme linkage via 3'-L-histidine	The covalent linkage of heme and a protein via 3'-L-histidine (otherwise known as pi-heme-histidine, pros-heme-histidine).	tmpzr1t_l9r_go_relaxed.owl	protein-haem linkage via 3'-L-histidine				RESID:AA0276									biological_process											owl:Class	
GO:0018873	biolink:NamedThing	atrazine metabolic process	The chemical reactions and pathways involving atrazine, a triazine ring-containing compound, widely used as a herbicide.	tmpzr1t_l9r_go_relaxed.owl	atrazine metabolism				UM-BBD_pathwayID:atr									biological_process											owl:Class	
GO:0060600	biolink:NamedThing	dichotomous subdivision of an epithelial terminal unit	The process in which an epithelial cord, rod or tube bifurcates at its end.	tmpzr1t_l9r_go_relaxed.owl	primary branching of an epithelium							dph	2009-05-14T02:14:50Z					biological_process											owl:Class	
GO:0019062	biolink:NamedThing	virion attachment to host cell	The process by which a virion protein binds to molecules on the host cellular surface or host cell surface projection.	tmpzr1t_l9r_go_relaxed.owl	virion attachment to host cell surface receptor|viral absorption|viral attachment to host cell				VZ:956									biological_process											owl:Class	
GO:0044650	biolink:NamedThing	adhesion of symbiont to host cell	The attachment of a symbiont to a host cell via adhesion molecules, general stickiness etc., either directly or indirectly.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-07-12T12:42:14Z					biological_process											owl:Class	
GO:0043188	biolink:NamedThing	cell septum edging	The cell wall material that surrounds the septum in fungal cells.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:1904827	biolink:NamedThing	negative regulation of hydrogen sulfide biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of hydrogen sulfide biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	inhibition of hydrogen sulfide biosynthesis|inhibition of hydrogen sulfide formation|down regulation of hydrogen sulphide biosynthetic process|negative regulation of hydrogen sulfide synthesis|down regulation of hydrogen sulfide biosynthetic process|down-regulation of hydrogen sulphide biosynthetic process|down-regulation of hydrogen sulfide anabolism|inhibition of hydrogen sulphide biosynthesis|negative regulation of hydrogen sulphide biosynthetic process|down regulation of hydrogen sulfide formation|down regulation of hydrogen sulfide biosynthesis|down regulation of hydrogen sulfide synthesis|downregulation of hydrogen sulfide synthesis|inhibition of hydrogen sulfide biosynthetic process|down-regulation of hydrogen sulfide biosynthesis|down regulation of hydrogen sulfide anabolism|negative regulation of hydrogen sulphide biosynthesis|downregulation of hydrogen sulfide anabolism|negative regulation of hydrogen sulfide biosynthesis|negative regulation of hydrogen sulfide anabolism|downregulation of hydrogen sulphide biosynthetic process|down-regulation of hydrogen sulphide biosynthesis|down-regulation of hydrogen sulfide formation|inhibition of hydrogen sulfide synthesis|downregulation of hydrogen sulfide biosynthetic process|inhibition of hydrogen sulphide biosynthetic process|down-regulation of hydrogen sulfide biosynthetic process|downregulation of hydrogen sulfide formation|inhibition of hydrogen sulfide anabolism|downregulation of hydrogen sulfide biosynthesis|down-regulation of hydrogen sulfide synthesis|negative regulation of hydrogen sulfide formation|down regulation of hydrogen sulphide biosynthesis|downregulation of hydrogen sulphide biosynthesis							rph	2015-11-24T10:15:34Z					biological_process											owl:Class	
GO:0051175	biolink:NamedThing	negative regulation of sulfur metabolic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving sulfur or compounds containing sulfur.	tmpzr1t_l9r_go_relaxed.owl	inhibition of sulfur metabolic process|negative regulation of sulphur metabolic process|down-regulation of sulfur metabolic process|down regulation of sulfur metabolic process|downregulation of sulfur metabolic process|negative regulation of sulfur metabolism|negative regulation of sulphur metabolism													biological_process											owl:Class	
GO:0033685	biolink:NamedThing	negative regulation of luteinizing hormone secretion	Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of luteinizing hormone.	tmpzr1t_l9r_go_relaxed.owl	down regulation of luteinizing hormone secretion|downregulation of luteinizing hormone secretion|inhibition of luteinizing hormone secretion|down-regulation of luteinizing hormone secretion													biological_process											owl:Class	
GO:0033684	biolink:NamedThing	regulation of luteinizing hormone secretion	Any process that modulates the frequency, rate or extent of the regulated release of luteinizing hormone.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0009902	biolink:NamedThing	chloroplast relocation	The process in which chloroplasts in photosynthetic cells migrate toward illuminated sites to optimize photosynthesis and move away from excessively illuminated areas to protect the photosynthetic machinery.	tmpzr1t_l9r_go_relaxed.owl	chloroplast movement													biological_process											owl:Class	
GO:0038001	biolink:NamedThing	paracrine signaling	The transfer of information from one cell to another, where the signal travels from the signal-producing cell to the receiving cell by passive diffusion or bulk flow in intercellular fluid. The signaling cell and the receiving cell are usually in the vicinity of each other.	tmpzr1t_l9r_go_relaxed.owl	paracrine signalling					This term should be used with caution, and only used when the signaling between cells has been clearly distinguished from endocrine signaling.		bf	2011-02-25T02:11:00Z					biological_process											owl:Class	
GO:0007267	biolink:NamedThing	cell-cell signaling	Any process that mediates the transfer of information from one cell to another. This process includes signal transduction in the receiving cell and, where applicable, release of a ligand and any processes that actively facilitate its transport and presentation to the receiving cell.  Examples include signaling via soluble ligands, via cell adhesion molecules and via gap junctions.	tmpzr1t_l9r_go_relaxed.owl	cell-cell signalling													biological_process											owl:Class	
GO:0001594	biolink:NamedThing	trace-amine receptor activity	Combining with a trace amine to initiate a change in cell activity. Trace amines are biogenic amines that are synthesized from aromatic amino acids and are substrates for monoamine oxidase, and are therefore detectable only at trace levels in mammals.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0008227	biolink:NamedThing	G protein-coupled amine receptor activity	Combining with an extracellular amine and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.	tmpzr1t_l9r_go_relaxed.owl	G-protein coupled amine receptor activity|amine receptor activity, G-protein coupled|biogenic amine receptor													molecular_function											owl:Class	
GO:0019646	biolink:NamedThing	aerobic electron transport chain	A process in which a series of electron carriers operate together to transfer electrons from donors such as NADH and FADH2 to oxygen to generate a transmembrane electrochemical gradient.	tmpzr1t_l9r_go_relaxed.owl	ubiquinone-8-O2 electron transport|succinate-O2 electron transport|NADH-O2 electron transport											GO:0006137|GO:0006136|GO:0006138		biological_process											owl:Class	
GO:0102058	biolink:NamedThing	jasmonoyl-leucine synthetase activity	Catalysis of the reaction: L-leucine  + ATP(4-) + a jasmonic acid <=> AMP(2-) + diphosphoric acid + a jasmonoyl-leucine.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-10459|EC:6.3.2.52|RHEA:55772									molecular_function											owl:Class	
GO:0042419	biolink:NamedThing	epinephrine catabolic process	The chemical reactions and pathways resulting in the breakdown of epinephrine, a hormone produced by the medulla of the adrenal glands that increases heart activity, improves the power and prolongs the action of muscles, and increases the rate and depth of breathing. It is synthesized by the methylation of norepinephrine.	tmpzr1t_l9r_go_relaxed.owl	epinephrine catabolism|adrenaline catabolism|epinephrine breakdown|adrenaline catabolic process|epinephrine degradation													biological_process											owl:Class	
GO:0042424	biolink:NamedThing	catecholamine catabolic process	The chemical reactions and pathways resulting in the breakdown of any of a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine.	tmpzr1t_l9r_go_relaxed.owl	catecholamine degradation|catecholamine catabolism|catecholamine breakdown													biological_process											owl:Class	
GO:0005164	biolink:NamedThing	tumor necrosis factor receptor binding	Binding to a tumor necrosis factor receptor.	tmpzr1t_l9r_go_relaxed.owl	TNF receptor binding|tumor necrosis factor|tumor necrosis factor receptor ligand													molecular_function											owl:Class	
GO:0032813	biolink:NamedThing	tumor necrosis factor receptor superfamily binding	Binding to a member of the tumor necrosis factor receptor superfamily.	tmpzr1t_l9r_go_relaxed.owl	TNF receptor superfamily binding													molecular_function											owl:Class	
GO:1902155	biolink:NamedThing	regulation of response to G1 DNA damage checkpoint signaling	Any process that modulates the frequency, rate or extent of response to G1 DNA damage checkpoint signaling.	tmpzr1t_l9r_go_relaxed.owl	regulation of response to mitotic cell cycle G1/S transition DNA damage checkpoint signaling|regulation of response to signal involved in mitotic cell cycle G1/S transition DNA damage checkpoint|regulation of mitotic cell cycle G1/S transition DNA damage checkpoint effector process							jl	2013-05-21T15:44:53Z					biological_process											owl:Class	
GO:1902153	biolink:NamedThing	regulation of response to DNA damage checkpoint signaling	Any process that modulates the frequency, rate or extent of response to DNA damage checkpoint signaling.	tmpzr1t_l9r_go_relaxed.owl	regulation of DNA damage checkpoint effector process|regulation of response to signal involved in DNA damage checkpoint							jl	2013-05-21T15:44:39Z					biological_process											owl:Class	
GO:0007218	biolink:NamedThing	neuropeptide signaling pathway	The series of molecular signals generated as a consequence of a peptide neurotransmitter binding to a cell surface receptor.	tmpzr1t_l9r_go_relaxed.owl	neuropeptide signalling pathway													biological_process											owl:Class	
GO:1905131	biolink:NamedThing	carcinine transmembrane transporter activity	Enables the transfer of carcinine from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl								dph	2016-04-12T15:18:25Z					molecular_function											owl:Class	
GO:1902385	biolink:NamedThing	glycyrrhetinate catabolic process	The chemical reactions and pathways resulting in the breakdown of glycyrrhetinate.	tmpzr1t_l9r_go_relaxed.owl	glycyrrhetinate breakdown|glycyrrhetinate degradation|glycyrrhetinate catabolism							ms	2013-09-03T12:56:10Z					biological_process											owl:Class	
GO:0052544	biolink:NamedThing	defense response by callose deposition in cell wall	Any process in which callose is transported to, and/or maintained in, the cell wall during the defense response. Callose is a linear 1,3-beta-d-glucan formed from UDP-glucose and is found in certain plant cell walls.	tmpzr1t_l9r_go_relaxed.owl	cell wall callose localization during defense response|cell wall callose deposition during defense response|callose localization in cell wall during defense response|callose deposition in cell wall during defense response													biological_process											owl:Class	
GO:0052482	biolink:NamedThing	defense response by cell wall thickening	A type of cell wall modification, in which the cell wall is reinforced and made thicker, that occurs as part of the defense response of an organism.	tmpzr1t_l9r_go_relaxed.owl	cell wall thickening during defense response													biological_process											owl:Class	
GO:1902243	biolink:NamedThing	copal-8-ol diphosphate(3-) biosynthetic process	The chemical reactions and pathways resulting in the formation of copal-8-ol diphosphate(3-).	tmpzr1t_l9r_go_relaxed.owl	copal-8-ol diphosphate(3-) biosynthesis|copal-8-ol diphosphate(3-) synthesis|copal-8-ol diphosphate(3-) formation|copal-8-ol diphosphate(3-) anabolism							ms	2013-06-20T09:09:38Z					biological_process											owl:Class	
GO:0018235	biolink:NamedThing	peptidyl-lysine carboxylation	The modification of peptidyl-lysine to form peptidyl-N6-carboxy-L-lysine.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0114									biological_process											owl:Class	
GO:0021959	biolink:NamedThing	cuneatus tract morphogenesis	Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the dorsal root ganglion towards target cells in the medulla. This axonal process is a member of those that make up the cuneatus tract, a group of axons that are from neurons involved in proprioception from the upper trunk and upper limb.	tmpzr1t_l9r_go_relaxed.owl	tract of Burdach morphogenesis													biological_process											owl:Class	
GO:0045725	biolink:NamedThing	positive regulation of glycogen biosynthetic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glycogen.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of glycogen biosynthetic process|positive regulation of glycogen biosynthesis|up regulation of glycogen biosynthetic process|positive regulation of glycogen formation|positive regulation of glycogen synthesis|upregulation of glycogen biosynthetic process|activation of glycogen biosynthetic process|stimulation of glycogen biosynthetic process|positive regulation of glycogen anabolism													biological_process											owl:Class	
GO:0005979	biolink:NamedThing	regulation of glycogen biosynthetic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glycogen.	tmpzr1t_l9r_go_relaxed.owl	regulation of glycogen formation|regulation of glycogen biosynthesis|regulation of glycogen synthesis|regulation of glycogen anabolism													biological_process											owl:Class	
GO:0004895	biolink:NamedThing	cell adhesion receptor activity	The binding by a cell-adhesion protein on the cell surface to an extracellular matrix component, to mediate adhesion of the cell to the external substrate or to another cell and to initiate intracellular signaling. Cell adhesion receptors include integrins and cadherins.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/15237				Reinstated term from obsolete.								molecular_function											owl:Class	
GO:0098631	biolink:NamedThing	cell adhesion mediator activity	The binding by a cell-adhesion protein on a cell surface to an adhesion molecule on another cell surface, to mediate adhesion of the cell to the external substrate or to another cell.	tmpzr1t_l9r_go_relaxed.owl	cell adhesion molecule|protein binding involved in cell adhesion													molecular_function											owl:Class	
GO:0009153	biolink:NamedThing	purine deoxyribonucleotide biosynthetic process	The chemical reactions and pathways resulting in the formation of purine deoxyribonucleotide, a compound consisting of deoxyribonucleoside (a purine base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.	tmpzr1t_l9r_go_relaxed.owl	purine deoxyribonucleotide formation|purine deoxyribonucleotide synthesis|purine deoxyribonucleotide biosynthesis|purine deoxyribonucleotide anabolism													biological_process											owl:Class	
GO:1900896	biolink:NamedThing	regulation of heptadecane biosynthetic process	Any process that modulates the frequency, rate or extent of heptadecane biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of heptadecane anabolism|regulation of heptadecane synthesis|regulation of heptadecane formation|regulation of heptadecane biosynthesis							tt	2012-06-13T03:27:38Z					biological_process											owl:Class	
GO:1900899	biolink:NamedThing	regulation of heptadecane metabolic process	Any process that modulates the frequency, rate or extent of heptadecane metabolic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of heptadecane metabolism							tt	2012-06-13T03:30:03Z					biological_process											owl:Class	
GO:0010732	biolink:NamedThing	regulation of protein glutathionylation	Any process that modulates the rate, frequency, or extent of protein glutathionylation. Protein glutathionylation is the protein modification process in which a glutathione molecule is added to a protein amino acid through a disulfide linkage.	tmpzr1t_l9r_go_relaxed.owl	regulation of protein amino acid glutathionylation													biological_process											owl:Class	
GO:0021674	biolink:NamedThing	rhombomere 8 morphogenesis	The process in which the anatomical structure of rhombomere 8 is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0021593	biolink:NamedThing	rhombomere morphogenesis	The process in which the anatomical structure of the rhombomere is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0050854	biolink:NamedThing	regulation of antigen receptor-mediated signaling pathway	Any process that modulates the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a B- or T cell.	tmpzr1t_l9r_go_relaxed.owl	regulation of antigen receptor mediated signalling pathway													biological_process											owl:Class	
GO:0033543	biolink:NamedThing	fatty acid beta-oxidation, unsaturated, even number, reductase/isomerase pathway	A fatty acid beta-oxidation pathway by which fatty acids having cis-double bonds on even-numbered carbons are degraded. In this pathway, the intermediate 2,4-dienoyl-CoA is converted to trans-2-enoyl-CoA by 2,4-dienoyl-CoA reductase and delta3-delta2-enoyl-CoA isomerase; trans-2-enoyl-CoA returns to the core beta-oxidation pathway for further degradation. Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and ends when only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively).	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0033542	biolink:NamedThing	fatty acid beta-oxidation, unsaturated, even number	A fatty acid beta-oxidation pathway by which fatty acids having cis-double bonds on even-numbered carbons are degraded. Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and ends when only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively).	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:PWY-5138									biological_process											owl:Class	
GO:0034334	biolink:NamedThing	adherens junction maintenance	The maintenance of an adherens junction. An adherens junction is a cell-cell junction composed of the epithelial cadherin-catenin complex at which the cytoplasmic face of the plasma membrane is attached to actin filaments.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0045217	biolink:NamedThing	cell-cell junction maintenance	The maintenance of junctions between cells.	tmpzr1t_l9r_go_relaxed.owl	intercellular junction maintenance													biological_process											owl:Class	
GO:0032390	biolink:NamedThing	MutLbeta complex	A heterodimer involved in the recognition of base-base and small insertion/deletion mismatches. In human the complex consists of two subunits, MLH1 and PMS1.	tmpzr1t_l9r_go_relaxed.owl	MMR complex|MLH1/PMS1 complex													cellular_component											owl:Class	
GO:0032300	biolink:NamedThing	mismatch repair complex	Any complex formed of proteins that act in mismatch repair.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0042157	biolink:NamedThing	lipoprotein metabolic process	The chemical reactions and pathways involving any conjugated, water-soluble protein in which the covalently attached nonprotein group consists of a lipid or lipids.	tmpzr1t_l9r_go_relaxed.owl	lipoprotein metabolism													biological_process											owl:Class	
GO:0110042	biolink:NamedThing	negative regulation of pharynx morphogenesis	Any process that stops, prevents, or reduces the frequency, rate or extent of pharynx morphogenesis.	tmpzr1t_l9r_go_relaxed.owl								kmv	2017-07-24T21:05:08Z					biological_process											owl:Class	
GO:0010129	biolink:NamedThing	anaerobic cyclohexane-1-carboxylate catabolic process	The chemical reactions and pathways resulting in the breakdown of cyclohexane-1-carboxylate, a alicyclic acid, in the absence of oxygen.	tmpzr1t_l9r_go_relaxed.owl	anaerobic cyclohexane-1-carboxylate breakdown|anaerobic cyclohexane-1-carboxylate catabolism|anaerobic cyclohexane-1-carboxylate degradation				MetaCyc:PWY-301									biological_process											owl:Class	
GO:0102982	biolink:NamedThing	UDP-3-dehydro-alpha-D-glucose dehydrogenase activity	Catalysis of the reaction: UDP-alpha-D-glucose + NAD <=> H+ + UDP-3-keto-alpha-D-glucose + NADH.	tmpzr1t_l9r_go_relaxed.owl					RHEA:35755|MetaCyc:RXN-9578									molecular_function											owl:Class	
GO:0016168	biolink:NamedThing	chlorophyll binding	Binding to a chlorophyll; a compound of magnesium complexed in a porphyrin (tetrapyrrole) ring and which functions as a photosynthetic pigment.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0046906	biolink:NamedThing	tetrapyrrole binding	Binding to a tetrapyrrole, a compound containing four pyrrole nuclei variously substituted and linked to each other through carbons at the alpha position.	tmpzr1t_l9r_go_relaxed.owl	porphyrin binding													molecular_function											owl:Class	
GO:0002701	biolink:NamedThing	negative regulation of production of molecular mediator of immune response	Any process that stops, prevents, or reduces the frequency, rate, or extent of the production of molecular mediator of immune response.	tmpzr1t_l9r_go_relaxed.owl	inhibition of production of molecular mediator of immune response|down regulation of production of molecular mediator of immune response|downregulation of production of molecular mediator of immune response|down-regulation of production of molecular mediator of immune response													biological_process											owl:Class	
GO:0030171	biolink:NamedThing	voltage-gated proton channel activity	Enables the transmembrane transfer of a proton by a voltage-gated channel. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.	tmpzr1t_l9r_go_relaxed.owl	voltage gated proton channel activity|voltage-dependent proton channel activity													molecular_function											owl:Class	
GO:0015252	biolink:NamedThing	proton channel activity	Enables the facilitated diffusion of a hydrogen ion (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.	tmpzr1t_l9r_go_relaxed.owl	hydrogen ion channel activity													molecular_function											owl:Class	
GO:0007288	biolink:NamedThing	sperm axoneme assembly	The assembly and organization of the sperm flagellar axoneme, the bundle of microtubules and associated proteins that forms the core of the eukaryotic sperm flagellum, and is responsible for movement.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1903364	biolink:NamedThing	positive regulation of cellular protein catabolic process	Any process that activates or increases the frequency, rate or extent of cellular protein catabolic process.	tmpzr1t_l9r_go_relaxed.owl	up regulation of cellular protein breakdown|positive regulation of cyclin catabolic process|positive regulation of cyclin breakdown|up-regulation of cellular protein catabolism|positive regulation of cellular protein breakdown|positive regulation of cellular protein catabolism|up regulation of cellular protein catabolism|positive regulation of cyclin degradation|positive regulation of degradation of cyclin|activation of cellular protein degradation|activation of cellular protein catabolism|positive regulation of cellular protein degradation|up regulation of cellular protein catabolic process|activation of cellular protein breakdown|positive regulation of cyclin catabolism|up regulation of cellular protein degradation|up-regulation of cellular protein catabolic process|upregulation of cellular protein breakdown|up-regulation of cellular protein degradation|up-regulation of cellular protein breakdown|activation of cellular protein catabolic process|upregulation of cellular protein degradation|upregulation of cellular protein catabolic process|upregulation of cellular protein catabolism							kmv	2014-08-21T15:06:01Z			GO:2000600		biological_process											owl:Class	
GO:1903362	biolink:NamedThing	regulation of cellular protein catabolic process	Any process that modulates the frequency, rate or extent of cellular protein catabolic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of cyclin catabolism|regulation of cellular protein breakdown|regulation of degradation of cyclin|regulation of cellular protein degradation|regulation of cyclin breakdown|regulation of cyclin catabolic process|regulation of cellular protein catabolism|regulation of cyclin degradation							kmv	2014-08-21T15:05:45Z			GO:2000598		biological_process											owl:Class	
GO:0016817	biolink:NamedThing	hydrolase activity, acting on acid anhydrides	Catalysis of the hydrolysis of any acid anhydride.	tmpzr1t_l9r_go_relaxed.owl	hydrolase activity, acting on acid anhydrides, involved in cellular and subcellular movement				EC:3.6.-.-									molecular_function											owl:Class	
GO:0061256	biolink:NamedThing	mesonephric glomerular visceral epithelial cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a mesonephric glomerular visceral epithelial cell. A mesonephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the mesonephros.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-08-30T02:03:38Z					biological_process											owl:Class	
GO:1904244	biolink:NamedThing	positive regulation of pancreatic trypsinogen secretion	Any process that activates or increases the frequency, rate or extent of pancreatic trypsinogen secretion.	tmpzr1t_l9r_go_relaxed.owl	activation of pancreatic trypsinogen secretion|upregulation of pancreatic trypsinogen secretion|up-regulation of pancreatic trypsinogen release|up regulation of pancreatic trypsinogen secretion|activation of pancreatic trypsinogen release|positive regulation of pancreatic trypsinogen release|up regulation of pancreatic trypsinogen release|upregulation of pancreatic trypsinogen release|up-regulation of pancreatic trypsinogen secretion							sl	2015-05-18T19:49:32Z					biological_process											owl:Class	
GO:0047441	biolink:NamedThing	5-dehydro-2-deoxyphosphogluconate aldolase activity	Catalysis of the reaction: 6-phospho-5-dehydro-2-deoxy-D-gluconate = 3-oxopropanoate + glycerone phosphate.	tmpzr1t_l9r_go_relaxed.owl	phospho-5-dehydro-2-deoxygluconate aldolase activity|phospho-5-keto-2-deoxygluconate aldolase activity|5-dehydro-2-deoxy-D-gluconate-6-phosphate malonate-semialdehyde-lyase activity|5-dehydro-2-deoxy-D-gluconate-6-phosphate malonate-semialdehyde-lyase (pyruvate-forming)				RHEA:13177|KEGG_REACTION:R05378|MetaCyc:4.1.2.29-RXN|EC:4.1.2.29									molecular_function											owl:Class	
GO:0050762	biolink:NamedThing	depsipeptide catabolic process	The chemical reactions and pathways resulting in the breakdown of depsipeptides, a linear or cyclic compound composed of both amino acids and hydroxy acids in peptide and ester bonds respectively.	tmpzr1t_l9r_go_relaxed.owl	depsipeptide catabolism|depsipeptide degradation|depsipeptide breakdown													biological_process											owl:Class	
GO:2000423	biolink:NamedThing	negative regulation of eosinophil chemotaxis	Any process that stops, prevents or reduces the frequency, rate or extent of eosinophil chemotaxis.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-02-24T01:17:12Z					biological_process											owl:Class	
GO:2001283	biolink:NamedThing	Roundabout signaling pathway involved in muscle cell chemotaxis toward tendon cell	Any Roundabout signaling pathway that is involved in the directed movement of a muscle cell towards a tendon cell in response to an external stimulus.	tmpzr1t_l9r_go_relaxed.owl	Roundabout signalling pathway involved in muscle cell chemotaxis toward tendon cell|ROBO/SLIT signaling pathway involved in muscle cell chemotaxis towards tendon cell|ROBO/SLIT signaling pathway involved in muscle cell attraction|Roundabout signalling pathway involved in muscle cell attraction|ROBO signaling pathway involved in muscle cell chemotaxis toward tendon cell|Roundabout signaling pathway involved in muscle cell attraction|ROBO signaling pathway involved in muscle cell chemotaxis towards tendon cell|ROBO/SLIT signaling pathway involved in muscle cell chemotaxis toward tendon cell|Roundabout signalling pathway involved in muscle cell chemotaxis towards tendon cell|Roundabout signaling pathway involved in muscle cell chemotaxis towards tendon cell|ROBO signaling pathway involved in muscle cell attraction							bf	2011-12-15T10:42:03Z					biological_process											owl:Class	
GO:0035385	biolink:NamedThing	Roundabout signaling pathway	A series of molecular signals initiated by the binding of a SLIT protein to a Roundabout (ROBO) family receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.	tmpzr1t_l9r_go_relaxed.owl	Roundabout signalling pathway|ROBO/SLIT signaling pathway|ROBO signaling pathway							bf	2010-03-18T02:38:31Z					biological_process											owl:Class	
GO:0044283	biolink:NamedThing	small molecule biosynthetic process	The chemical reactions and pathways resulting in the formation of small molecules, any low molecular weight, monomeric, non-encoded molecule.	tmpzr1t_l9r_go_relaxed.owl	small molecule biosynthesis					Small molecules in GO include monosaccharides but exclude disaccharides and polysaccharides.		jl	2010-01-26T12:06:49Z					biological_process											owl:Class	
GO:0008681	biolink:NamedThing	2-octaprenyl-6-methoxyphenol hydroxylase activity	Catalysis of the reaction: 2-octaprenyl-6-methoxyphenol + O2 + 4 H+ = 2-octaprenyl-6-methoxy-1,4-benzoquinol + H2O.	tmpzr1t_l9r_go_relaxed.owl					RHEA:29407|MetaCyc:2-OCTAPRENYL-6-METHOXYPHENOL-HYDROX-RXN									molecular_function											owl:Class	
GO:0035499	biolink:NamedThing	carnosine biosynthetic process	The chemical reactions and pathways resulting in the formation of the dipeptide beta-alanyl-L-histidine (carnosine).	tmpzr1t_l9r_go_relaxed.owl	carnosine formation|carnosine biosynthesis|carnosine anabolism|carnosine synthesis							bf	2010-04-29T01:20:56Z					biological_process											owl:Class	
GO:0043043	biolink:NamedThing	peptide biosynthetic process	The chemical reactions and pathways resulting in the formation of peptides, compounds of 2 or more (but usually less than 100) amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another. This may include the translation of a precursor protein and its subsequent processing into a functional peptide.	tmpzr1t_l9r_go_relaxed.owl	peptide formation|peptide biosynthesis|peptide synthesis|peptide anabolism													biological_process											owl:Class	
GO:0016145	biolink:NamedThing	S-glycoside catabolic process	The chemical reactions and pathways resulting in the breakdown of S-glycosides, any compound in which a glycosyl group has been substituted into a thiol group.	tmpzr1t_l9r_go_relaxed.owl	thioglycoside catabolism|thioglycoside catabolic process|S-glycoside breakdown|S-glycoside catabolism|S-glycoside degradation													biological_process											owl:Class	
GO:1903471	biolink:NamedThing	regulation of mitotic actomyosin contractile ring contraction	Any process that modulates the frequency, rate or extent of mitotic actomyosin contractile ring contraction.	tmpzr1t_l9r_go_relaxed.owl	regulation of mitotic actomyosin contractile ring constriction|regulation of cytokinesis, actomyosin ring contraction involved in mitotic cell cycle|regulation of contractile ring contraction involved in cell cycle cytokinesis involved in mitotic cell cycle	https://github.com/geneontology/go-ontology/issues/21855						vw	2014-09-23T14:10:22Z					biological_process											owl:Class	
GO:1903436	biolink:NamedThing	regulation of mitotic cytokinetic process	Any process that modulates the frequency, rate or extent of mitotic cytokinetic process.	tmpzr1t_l9r_go_relaxed.owl								tb	2014-09-15T23:11:38Z					biological_process											owl:Class	
GO:1900864	biolink:NamedThing	mitochondrial RNA modification	Any RNA modification that takes place in mitochondrion.	tmpzr1t_l9r_go_relaxed.owl	mitochondrial RNA editing							tb	2012-06-11T10:49:56Z					biological_process											owl:Class	
GO:0009451	biolink:NamedThing	RNA modification	The covalent alteration of one or more nucleotides within an RNA molecule to produce an RNA molecule with a sequence that differs from that coded genetically.	tmpzr1t_l9r_go_relaxed.owl	RNA editing				Wikipedia:RNA_editing	The term 'RNA editing' (GO:0016547) was merged into 'RNA modification' (GO:0009451) on the basis of statements in the preface of Modification and Editing of RNA (ISBN:1555811337) that there is no clear distinction between modification and editing.						GO:0016547		biological_process											owl:Class	
GO:0051293	biolink:NamedThing	establishment of spindle localization	The directed movement of the spindle to a specific location in the cell.	tmpzr1t_l9r_go_relaxed.owl	spindle positioning|establishment of spindle localisation													biological_process											owl:Class	
GO:0051653	biolink:NamedThing	spindle localization	Any process in which is the spindle is transported to, and/or maintained in, a specific location.	tmpzr1t_l9r_go_relaxed.owl	spindle localisation|establishment and maintenance of spindle localization													biological_process											owl:Class	
GO:0071330	biolink:NamedThing	cellular response to trehalose-6-phosphate stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a trehalose-6-phosphate stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-12-10T05:32:52Z					biological_process											owl:Class	
GO:0071324	biolink:NamedThing	cellular response to disaccharide stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disaccharide stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-12-10T05:26:14Z					biological_process											owl:Class	
GO:0072742	biolink:NamedThing	SAGA complex localization to transcription regulatory region	Any process in which a SAGA complex is transported to, or maintained in, a specific location in the transcription regulatory region of a gene.	tmpzr1t_l9r_go_relaxed.owl	SAGA complex localization to promoter|SAGA complex recruitment							mah	2012-08-24T10:36:03Z					biological_process											owl:Class	
GO:0032462	biolink:NamedThing	regulation of protein homooligomerization	Any process that modulates the frequency, rate or extent of protein homooligomerization.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0032459	biolink:NamedThing	regulation of protein oligomerization	Any process that modulates the frequency, rate or extent of protein oligomerization.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0036171	biolink:NamedThing	filamentous growth of a population of unicellular organisms in response to chemical stimulus	The process in which a group of unicellular organisms grow in a threadlike, filamentous shape in response to a chemical stimulus.	tmpzr1t_l9r_go_relaxed.owl								bf	2012-03-27T03:53:28Z					biological_process											owl:Class	
GO:2000110	biolink:NamedThing	negative regulation of macrophage apoptotic process	Any process that stops, prevents, or reduces the frequency, rate or extent of macrophage apoptotic process.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of AICD|negative regulation of macrophage apoptosis|negative regulation of activation-induced cell death							mah	2010-09-15T01:44:18Z					biological_process											owl:Class	
GO:0003677	biolink:NamedThing	DNA binding	Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).	tmpzr1t_l9r_go_relaxed.owl	microtubule/chromatin interaction|plasmid binding|structure specific DNA binding|structure-specific DNA binding											GO:0043566		molecular_function											owl:Class	
GO:0006379	biolink:NamedThing	mRNA cleavage	Any process in which a pre-mRNA or mRNA molecule is cleaved at specific sites or in a regulated manner.	tmpzr1t_l9r_go_relaxed.owl	cleavage stimulation factor activity													biological_process											owl:Class	
GO:0016071	biolink:NamedThing	mRNA metabolic process	The chemical reactions and pathways involving mRNA, messenger RNA, which is responsible for carrying the coded genetic 'message', transcribed from DNA, to sites of protein assembly at the ribosomes.	tmpzr1t_l9r_go_relaxed.owl	mRNA metabolism													biological_process											owl:Class	
GO:0035406	biolink:NamedThing	histone-tyrosine phosphorylation	The modification of histones by addition of a phosphate group to a tyrosine residue.	tmpzr1t_l9r_go_relaxed.owl	histone tyrosine phosphorylation							bf	2010-03-24T10:10:16Z					biological_process											owl:Class	
GO:0016572	biolink:NamedThing	histone phosphorylation	The modification of histones by addition of phosphate groups.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0010919	biolink:NamedThing	regulation of inositol phosphate biosynthetic process	Any process that modulates the rate, frequency or extent of inositol phosphate biosynthesis. Inositol phosphate biosynthetic processes are the chemical reactions and pathways resulting in the formation of an inositol phosphate, 1,2,3,4,5,6-cyclohexanehexol, with one or more phosphate groups attached.	tmpzr1t_l9r_go_relaxed.owl	regulation of inositol phosphate biosynthesis													biological_process											owl:Class	
GO:0043255	biolink:NamedThing	regulation of carbohydrate biosynthetic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of carbohydrates.	tmpzr1t_l9r_go_relaxed.owl	regulation of carbohydrate synthesis|regulation of carbohydrate anabolism|regulation of carbohydrate formation|regulation of carbohydrate biosynthesis													biological_process											owl:Class	
GO:1902128	biolink:NamedThing	(-)-lariciresinol catabolic process	The chemical reactions and pathways resulting in the breakdown of (-)-lariciresinol.	tmpzr1t_l9r_go_relaxed.owl	(-)-lariciresinol degradation|(-)-lariciresinol breakdown|(-)-lariciresinol catabolism							ms	2013-05-21T08:49:38Z					biological_process											owl:Class	
GO:0046273	biolink:NamedThing	lignan catabolic process	The chemical reactions and pathways resulting in the breakdown of lignans, any member of a class of plant metabolites related to lignins. Lignans are usually found as phenylpropanoid dimers in which the phenylpropanoid units are linked tail to tail and thus having a 2,3 dibenzylbutane skeleton, but higher oligomers can also exist.	tmpzr1t_l9r_go_relaxed.owl	lignan degradation|lignan breakdown|lignan catabolism													biological_process											owl:Class	
GO:1902130	biolink:NamedThing	(+)-lariciresinol metabolic process	The chemical reactions and pathways involving (+)-lariciresinol.	tmpzr1t_l9r_go_relaxed.owl	(+)-lariciresinol metabolism							ms	2013-05-21T08:49:49Z					biological_process											owl:Class	
GO:0009231	biolink:NamedThing	riboflavin biosynthetic process	The chemical reactions and pathways resulting in the formation of riboflavin (vitamin B2), the precursor for the coenzymes flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD).	tmpzr1t_l9r_go_relaxed.owl	vitamin B2 biosynthetic process|riboflavin formation|vitamin G biosynthetic process|riboflavin synthesis|riboflavin anabolism|riboflavin biosynthesis|vitamin B2 biosynthesis|vitamin G biosynthesis				Wikipedia:Riboflavin|MetaCyc:RIBOSYN2-PWY									biological_process											owl:Class	
GO:0006771	biolink:NamedThing	riboflavin metabolic process	The chemical reactions and pathways involving riboflavin (vitamin B2), the precursor for the coenzymes flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD).	tmpzr1t_l9r_go_relaxed.owl	vitamin G metabolic process|vitamin B2 metabolic process|riboflavin metabolism|vitamin B2 metabolism|vitamin G metabolism				Wikipedia:Riboflavin									biological_process											owl:Class	
GO:0061287	biolink:NamedThing	mesonephric capsule formation	The developmental process pertaining to the initial formation of a mesonephric capsule from unspecified parts. The mesonephric capsule is the tough fibrous layer surrounding the mesonephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-09-02T01:55:03Z					biological_process											owl:Class	
GO:0072129	biolink:NamedThing	renal capsule formation	The developmental process pertaining to the initial formation of a renal capsule from unspecified parts. The renal capsule is the tough fibrous layer surrounding the kidney, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage. During development, it comprises a single layer of flattened cells that lie just above the cortical stroma and the condensed mesenchyme of the nephrogenic zone. It is in this region that the early stages of nephron induction and formation of new generations ureteric bud branches occur, as the kidney expands.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-02-22T02:08:14Z					biological_process											owl:Class	
GO:0060610	biolink:NamedThing	mesenchymal cell differentiation involved in mammary gland development	The process in which a relatively unspecialized cell acquires specialized features of a mammary gland mesenchymal cell. Mammary gland mesenchymal cells form a loosely connected network of cells that surround the mammary ducts.	tmpzr1t_l9r_go_relaxed.owl	mammary gland mesenchymal cell differentiation							dph	2009-05-15T12:17:06Z					biological_process											owl:Class	
GO:0048762	biolink:NamedThing	mesenchymal cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal cell. A mesenchymal cell is a loosely associated cell that is part of the connective tissue in an organism. Mesenchymal cells give rise to more mature connective tissue cell types.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1902794	biolink:NamedThing	siRNA-independent facultative heterochromatin assembly	The assembly of facultative heterochromatin to form a heterochromatin domain, enriched in histone H3 methylated on lysine 9 (H3K9me), by a process independent of small interfering RNAs.	tmpzr1t_l9r_go_relaxed.owl	heterochromatin island formation|heterochromatin island assembly	https://github.com/geneontology/go-ontology/issues/22326						mah	2014-03-24T12:46:49Z					biological_process											owl:Class	
GO:0140718	biolink:NamedThing	facultative heterochromatin assembly	The assembly of facultative heterochromatin, heterochromatin that can be converted to euchromatin and allow transcription under specific contexts. These can be temporal (e.g., developmental states or specific cell-cycle stages), spatial (e.g., nuclear localization changes from the center to the periphery or vice versa due to exogenous factors/signals), or parental/heritable (e.g., monoallelic gene expression).	tmpzr1t_l9r_go_relaxed.owl	fHC assembly	https://github.com/geneontology/go-ontology/issues/22325						pg	2021-10-29T13:40:47Z					biological_process											owl:Class	
GO:1902924	biolink:NamedThing	poly(hydroxyalkanoate) biosynthetic process from glucose	The chemical reactions and pathways resulting in the formation of poly(hydroxyalkanoate) from glucose.	tmpzr1t_l9r_go_relaxed.owl	poly(hydroxyalkanoate) biosynthesis from glucose|poly(hydroxyalkanoate) synthesis from glucose|poly(hydroxyalkanoate) formation from glucose|poly(hydroxyalkanoate) anabolism from glucose							tt	2014-04-21T22:49:07Z					biological_process											owl:Class	
GO:0039502	biolink:NamedThing	suppression by virus of host type I interferon-mediated signaling pathway	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of type I interferon-mediated signaling in the host organism. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families.	tmpzr1t_l9r_go_relaxed.owl	inhibition of host interferon signaling pathway by virus|negative regulation by virus of host type I interferon-mediated signaling pathway|suppression by virus of host type I IFN-mediated signaling pathway|suppression by virus of host type I interferon-mediated signalling pathway				VZ:883			bf	2011-05-11T04:06:28Z					biological_process											owl:Class	
GO:0046640	biolink:NamedThing	regulation of alpha-beta T cell proliferation	Any process that modulates the frequency, rate or extent of alpha-beta T cell proliferation.	tmpzr1t_l9r_go_relaxed.owl	regulation of alpha-beta T lymphocyte proliferation|regulation of alpha-beta T-cell proliferation|regulation of alpha-beta T-lymphocyte proliferation													biological_process											owl:Class	
GO:0046634	biolink:NamedThing	regulation of alpha-beta T cell activation	Any process that modulates the frequency, rate or extent of alpha-beta T cell activation.	tmpzr1t_l9r_go_relaxed.owl	regulation of alpha-beta T-lymphocyte activation|regulation of alpha-beta T-cell activation|regulation of alpha-beta T lymphocyte activation													biological_process											owl:Class	
GO:0007287	biolink:NamedThing	Nebenkern assembly	Fusion of mitochondria during insect spermatid differentiation to form two masses, which wrap around each other to form a densely packed sphere called the Nebenkern.	tmpzr1t_l9r_go_relaxed.owl	Nebenkern formation					See also the cellular component term 'Nebenkern ; GO:0016006', and the fly_anatomy.ontology term 'Nebenkern ; FBbt:00004943'.								biological_process											owl:Class	
GO:0035583	biolink:NamedThing	sequestering of TGFbeta in extracellular matrix	Confining TGFbeta to the extracellular matrix (ECM) such that it is separated from other components of the signaling pathway, including its cell surface receptor. TGFbeta is secreted as part of a latent complex that is targeted to the extracellular matrix through latent-TGFbeta-binding protein (LTBP)-mediated association with matrix proteins.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of transforming growth factor beta receptor signaling pathway by extracellular matrix sequestering of TGFbeta|sequestering of TGFbeta LLC in extracellular matrix|negative regulation of transforming growth factor beta receptor signalling pathway by extracellular matrix sequestering of TGFbeta|sequestering of TGFbeta large latency complex in extracellular matrix							bf	2010-10-12T03:13:29Z					biological_process											owl:Class	
GO:0098816	biolink:NamedThing	mini excitatory postsynaptic potential	A process that leads to a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell, induced by the spontaneous release of a single vesicle of an excitatory neurotransmitter into the synapse.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0060079	biolink:NamedThing	excitatory postsynaptic potential	A process that leads to a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC) and makes it easier for the neuron to fire an action potential.	tmpzr1t_l9r_go_relaxed.owl	regulation of EPSP|regulation of excitatory post-synaptic membrane potential													biological_process											owl:Class	
GO:0018226	biolink:NamedThing	peptidyl-S-farnesyl-L-cysteine biosynthetic process from peptidyl-cysteine	The modification of peptidyl-cysteine to form peptidyl-S-farnesyl-L-cysteine; formation of S-farnesycysteine may be coupled with subsequent cleavage of a carboxy-terminal tripeptide for the CXXX motif and methyl esterification of the farnesylated cysteine; the residue may be found at the first position in the sequence motif C-X-X-(SAQCMT)* where the second and third positions are usually aliphatic.	tmpzr1t_l9r_go_relaxed.owl	peptidyl-S-farnesyl-L-cysteine formation from peptidyl-cysteine|peptidyl-S-farnesyl-L-cysteine synthesis from peptidyl-cysteine|peptidyl-S-farnesyl-L-cysteine anabolism from peptidyl-cysteine				RESID:AA0102									biological_process											owl:Class	
GO:0018343	biolink:NamedThing	protein farnesylation	The covalent attachment of a farnesyl group to a protein.	tmpzr1t_l9r_go_relaxed.owl	C-terminal protein farnesylation|protein amino acid farnesylation											GO:0018347		biological_process											owl:Class	
GO:0004314	biolink:NamedThing	[acyl-carrier-protein] S-malonyltransferase activity	Catalysis of the reaction: malonyl-CoA + [acyl-carrier protein] = CoA + malonyl-[acyl-carrier protein].	tmpzr1t_l9r_go_relaxed.owl	MCAT activity|malonyl coenzyme A-acyl carrier protein transacylase activity|FabD|malonyl transacylase activity|malonyl-CoA-acyl carrier protein transacylase activity|malonyl-CoA:acyl-carrier-protein S-malonyltransferase activity|malonyl-CoA:AcpM transacylase activity|acyl carrier proteinmalonyltransferase activity|malonyl-CoA:acyl carrier protein transacylase activity|malonyl transferase activity|malonyl-CoA:ACP transacylase activity|[acyl-carrier protein] S-malonyltransferase activity|acyl-carrier-protein S-malonyltransferase activity|ACP S-malonyltransferase activity|acyl carrier protein malonyltransferase activity|MAT				MetaCyc:MALONYL-COA-ACP-TRANSACYL-RXN|EC:2.3.1.39|Reactome:R-HSA-8933547									molecular_function											owl:Class	
GO:0004312	biolink:NamedThing	fatty acid synthase activity	Catalysis of the reaction: acetyl-CoA + n malonyl-CoA + 2n NADPH + 2n H+ = long-chain fatty acid + n+1 CoA + n CO2 + 2n NADP+.	tmpzr1t_l9r_go_relaxed.owl	acyl-CoA:malonyl-CoA C-acyltransferase (decarboxylating, oxoacyl- and enoyl-reducing and thioester-hydrolysing)|fatty-acid synthase activity				Reactome:R-HSA-75872|RHEA:14993|MetaCyc:FATTY-ACID-SYNTHASE-RXN|EC:2.3.1.85									molecular_function											owl:Class	
GO:0033703	biolink:NamedThing	3beta-hydroxy-5beta-steroid dehydrogenase activity	Catalysis of the reaction: 3beta-hydroxy-5beta-pregnane-20-one + NADP(+) = 5beta-pregnan-3,20-dione + H(+) + NADPH.	tmpzr1t_l9r_go_relaxed.owl	3beta-hydroxysteroid 5beta-oxidoreductase activity|3beta-hydroxysteroid 5beta-progesterone oxidoreductase activity|3beta-hydroxy-5beta-steroid:NADP+ 3-oxidoreductase activity				RHEA:22944|KEGG_REACTION:R06166|EC:1.1.1.277|MetaCyc:1.1.1.277-RXN									molecular_function											owl:Class	
GO:2000264	biolink:NamedThing	negative regulation of blood coagulation, extrinsic pathway	Any process that stops, prevents or reduces the frequency, rate or extent of blood coagulation, extrinsic pathway.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-11-23T11:44:42Z					biological_process											owl:Class	
GO:0030195	biolink:NamedThing	negative regulation of blood coagulation	Any process that stops, prevents, or reduces the frequency, rate or extent of blood coagulation.	tmpzr1t_l9r_go_relaxed.owl	downregulation of blood coagulation|inhibition of blood coagulation|down-regulation of blood coagulation|down regulation of blood coagulation													biological_process											owl:Class	
GO:0090514	biolink:NamedThing	L-tyrosine transmembrane import into vacuole	The directed movement of L-tyrosine into the vacuole across the vacuolar membrane.	tmpzr1t_l9r_go_relaxed.owl								tb	2012-12-14T11:25:52Z					biological_process											owl:Class	
GO:1900097	biolink:NamedThing	positive regulation of dosage compensation by inactivation of X chromosome	Any process that activates or increases the frequency, rate or extent of dosage compensation, by inactivation of X chromosome.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of Barr body formation|up-regulation of dosage compensation, by inactivation of X chromosome|upregulation of Barr body formation|positive regulation of X chromosome inactivation|up-regulation of chromosome inactivation|activation of X chromosome inactivation|up regulation of dosage compensation, by inactivation of X chromosome|activation of chromosome inactivation|activation of Barr body formation|up regulation of Barr body formation|up regulation of chromosome inactivation|positive regulation of chromosome inactivation|upregulation of dosage compensation, by inactivation of X chromosome|up-regulation of X chromosome inactivation|positive regulation of Barr body formation|up regulation of X chromosome inactivation|upregulation of X chromosome inactivation|activation of dosage compensation, by inactivation of X chromosome|upregulation of chromosome inactivation							hjd	2012-02-14T07:29:52Z					biological_process											owl:Class	
GO:2000317	biolink:NamedThing	negative regulation of T-helper 17 type immune response	Any process that stops, prevents or reduces the frequency, rate or extent of T-helper 17 type immune response.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of Th17 immune response							mah	2011-01-18T01:33:00Z					biological_process											owl:Class	
GO:0002823	biolink:NamedThing	negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	Any process that stops, prevents, or reduces the frequency, rate, or extent of an adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains. An example of this process is found in the Gnathostomata.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0002196	biolink:NamedThing	Ser-tRNA(Ala) hydrolase activity	Catalysis of the hydrolysis of misacylated Ser-tRNA(Ala).	tmpzr1t_l9r_go_relaxed.owl								hjd	2011-09-30T02:18:50Z					molecular_function											owl:Class	
GO:0002161	biolink:NamedThing	aminoacyl-tRNA editing activity	The hydrolysis of an incorrectly aminoacylated tRNA.	tmpzr1t_l9r_go_relaxed.owl	aminoacyl-tRNA hydrolysis activity|amino acid proofreading activity							hjd	2010-02-12T03:06:56Z					molecular_function											owl:Class	
GO:1900826	biolink:NamedThing	negative regulation of membrane depolarization during cardiac muscle cell action potential	Any process that stops, prevents or reduces the frequency, rate or extent of membrane depolarization during a cardiac muscle cell action potential.	tmpzr1t_l9r_go_relaxed.owl	downregulation of membrane depolarization during cardiac muscle cell action potential|inhibition of membrane depolarization during cardiac muscle cell action potential|down-regulation of membrane depolarization during of cardiac muscle cell action potential|down regulation of membrane depolarization during cardiac muscle cell action potential							rl	2012-06-06T04:15:40Z					biological_process											owl:Class	
GO:1901155	biolink:NamedThing	paromomycin biosynthetic process	The chemical reactions and pathways resulting in the formation of paromomycin.	tmpzr1t_l9r_go_relaxed.owl	paromomycin synthesis|paromomycin biosynthesis|paromomycin formation|paromomycin anabolism							yaf	2012-07-17T04:27:51Z					biological_process											owl:Class	
GO:0030648	biolink:NamedThing	aminoglycoside antibiotic biosynthetic process	The chemical reactions and pathways resulting in the formation of an aminoglycoside antibiotic, any member of a group of broad spectrum antibiotics, of similar toxicity and pharmacology, that contain an aminodeoxysugar, an amino- or guanidino-substituted inositol ring, and one or more residues of other sugars. The group includes streptomycin, neomycin, framycetin, kanamycin, paromomycin, and gentamicin.	tmpzr1t_l9r_go_relaxed.owl	aminoglycoside antibiotic formation|aminoglycoside antibiotic anabolism|aminoglycoside antibiotic synthesis|aminoglycoside antibiotic biosynthesis													biological_process											owl:Class	
GO:0046459	biolink:NamedThing	short-chain fatty acid metabolic process	The chemical reactions and pathways involving fatty acids with a chain length of less than C6.	tmpzr1t_l9r_go_relaxed.owl	short-chain fatty acid metabolism													biological_process											owl:Class	
GO:1902339	biolink:NamedThing	positive regulation of apoptotic process involved in morphogenesis	Any process that activates or increases the frequency, rate or extent of apoptotic process involved in morphogenesis.	tmpzr1t_l9r_go_relaxed.owl	activation of apoptosis involved in development|activation of apoptosis involved in morphogenesis|up regulation of apoptosis involved in morphogenesis|upregulation of morphogenetic apoptosis|up-regulation of morphogenetic apoptosis|upregulation of apoptotic process involved in morphogenesis|positive regulation of apoptosis involved in development|up regulation of morphogenetic apoptosis|up-regulation of apoptosis involved in morphogenesis|upregulation of apoptosis involved in morphogenesis|positive regulation of morphogenetic apoptosis|up regulation of apoptotic process involved in morphogenesis|activation of apoptotic process involved in morphogenesis|up-regulation of apoptotic process involved in morphogenesis|activation of morphogenetic apoptosis|upregulation of apoptosis involved in development|up regulation of apoptosis involved in development|up-regulation of apoptosis involved in development|positive regulation of apoptosis involved in morphogenesis							sart	2013-07-29T15:03:33Z					biological_process											owl:Class	
GO:0034628	biolink:NamedThing	'de novo' NAD biosynthetic process from aspartate	The chemical reactions and pathways resulting in the formation of nicotinamide adenine dinucleotide (NAD), beginning with the synthesis of aspartate from simpler precursors; biosynthesis may be of either the oxidized form, NAD, or the reduced form, NADH.	tmpzr1t_l9r_go_relaxed.owl	de novo NAD biosynthetic process from aspartate													biological_process											owl:Class	
GO:0034627	biolink:NamedThing	'de novo' NAD biosynthetic process	The chemical reactions and pathways resulting in the formation of nicotinamide adenine dinucleotide (NAD), beginning with the synthesis of tryptophan or aspartate from simpler precursors; biosynthesis may be of either the oxidized form, NAD, or the reduced form, NADH.	tmpzr1t_l9r_go_relaxed.owl	de novo NAD biosynthetic process													biological_process											owl:Class	
GO:0002664	biolink:NamedThing	regulation of T cell tolerance induction	Any process that modulates the frequency, rate, or extent of T cell tolerance induction.	tmpzr1t_l9r_go_relaxed.owl	regulation of T lymphocyte tolerance induction|regulation of T-cell tolerance induction|regulation of T-lymphocyte tolerance induction													biological_process											owl:Class	
GO:0002643	biolink:NamedThing	regulation of tolerance induction	Any process that modulates the frequency, rate, or extent of tolerance induction.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1904268	biolink:NamedThing	positive regulation of Schwann cell chemotaxis	Any process that activates or increases the frequency, rate or extent of Schwann cell chemotaxis.	tmpzr1t_l9r_go_relaxed.owl	upregulation of Schwann cell chemotaxis|up regulation of Schwann cell chemotaxis|activation of Schwann cell chemotaxis|up-regulation of Schwann cell chemotaxis							sl	2015-05-28T17:47:55Z					biological_process											owl:Class	
GO:0002559	biolink:NamedThing	type I hypersensitivity mediated by basophils	An inflammatory response driven by antigen recognition by antibodies bound to Fc receptors basophils, occurring within minutes after exposure of a sensitized individual to the antigen, and leading to the release of a variety of inflammatory mediators such as histamines.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0002560	biolink:NamedThing	basophil mediated immunity	Any process involved in the carrying out of an immune response by a basophil.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0014054	biolink:NamedThing	positive regulation of gamma-aminobutyric acid secretion	Any process that activates or increases the frequency, rate or extent of the regulated release of gamma-aminobutyric acid.	tmpzr1t_l9r_go_relaxed.owl	activation of gamma-aminobutyric acid secretion|upregulation of gamma-aminobutyric acid secretion|up regulation of gamma-aminobutyric acid secretion|up-regulation of gamma-aminobutyric acid secretion|positive regulation of GABA secretion|stimulation of gamma-aminobutyric acid secretion													biological_process											owl:Class	
GO:0015233	biolink:NamedThing	pantothenate transmembrane transporter activity	Enables the directed movement of pantothenate across a membrane. Pantothenate is the anion of pantothenic acid, the amide of beta-alanine and pantoic acid; it is a B complex vitamin that is a constituent of coenzyme A and is distributed ubiquitously in foods.	tmpzr1t_l9r_go_relaxed.owl	vitamin B5 transmembrane transporter activity|pantothenate transporter activity													molecular_function											owl:Class	
GO:0061001	biolink:NamedThing	regulation of dendritic spine morphogenesis	Any process that modulates the rate, frequency, or extent of dendritic spine morphogenesis, the process in which the anatomical structures of a dendritic spine are generated and organized. A dendritic spine is a protrusion from a dendrite and a specialized subcellular compartment involved in synaptic transmission.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-01-20T09:31:52Z					biological_process											owl:Class	
GO:0102771	biolink:NamedThing	sphingolipid very long chain fatty acid alpha-hydroxylase activity	Catalysis of the reaction: O2 + NADPH + H+ + a dihydroceramide = NADP + H2O + an alpha hydroxydihydroceramide.	tmpzr1t_l9r_go_relaxed.owl					RHEA:46512|MetaCyc:RXN-7796									molecular_function											owl:Class	
GO:0106317	biolink:NamedThing	methane monooxygenase NADH activity	Catalysis of the reaction: methane + NADH + H+ + O2 = methanol + NAD+ + H2O.	tmpzr1t_l9r_go_relaxed.owl					EC:1.14.13.25|RHEA:13637			hjd	2020-09-23T15:12:25Z					molecular_function											owl:Class	
GO:0015049	biolink:NamedThing	methane monooxygenase activity	Catalysis of the reaction: methane + NAD(P)H + H+ + O2 = methanol + NAD(P)+ + H2O.	tmpzr1t_l9r_go_relaxed.owl	methane,NAD(P)H:oxygen oxidoreductase (hydroxylating)|methane hydroxylase activity				EC:1.14.13.25|KEGG_REACTION:R01142|UM-BBD_enzymeID:e0007|MetaCyc:METHANE-MONOOXYGENASE-RXN|KEGG_REACTION:R01143									molecular_function											owl:Class	
GO:0009215	biolink:NamedThing	purine deoxyribonucleoside triphosphate metabolic process	The chemical reactions and pathways involving purine deoxyribonucleoside triphosphate, a compound consisting of a purine base linked to a deoxyribose sugar esterified with triphosphate on the sugar.	tmpzr1t_l9r_go_relaxed.owl	purine deoxyribonucleoside triphosphate metabolism													biological_process											owl:Class	
GO:0009192	biolink:NamedThing	deoxyribonucleoside diphosphate catabolic process	The chemical reactions and pathways resulting in the breakdown of a deoxyribonucleoside diphosphate, a compound consisting of a nucleobase linked to a deoxyribose sugar esterified with diphosphate on the sugar.	tmpzr1t_l9r_go_relaxed.owl	deoxyribonucleoside diphosphate degradation|deoxyribonucleoside diphosphate breakdown|deoxyribonucleoside diphosphate catabolism													biological_process											owl:Class	
GO:0048572	biolink:NamedThing	short-day photoperiodism	Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a day length that falls short of a particular duration known as the 'critical day length'. The critical day length varies between species. Although the term short-day is used, most species actually respond to the duration of the night, so that the response will occur when a period of darkness exceeds the number of hours defined by 24 hours minus the critical day length.	tmpzr1t_l9r_go_relaxed.owl	response to short-day photoperiod|response to short-day|long-night photoperiodism|response to long-night													biological_process											owl:Class	
GO:0009648	biolink:NamedThing	photoperiodism	Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a period of light or dark of a given length, measured relative to a particular duration known as the 'critical day length'. The critical day length varies between species.	tmpzr1t_l9r_go_relaxed.owl	response to night length|response to day length|response to photoperiod				Wikipedia:Photoperiodism									biological_process											owl:Class	
GO:0102028	biolink:NamedThing	cystathionine gamma-synthase activity (acts on O-phosphohomoserine)	Catalysis of the reaction: L-cysteine + O-phosphonato-L-homoserine = L-cystathionine + hydrogenphosphate.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:CYSPH-RXN|EC:2.5.1.48									molecular_function											owl:Class	
GO:1905274	biolink:NamedThing	regulation of modification of postsynaptic actin cytoskeleton	Any process that modulates the frequency, rate or extent of modification of postsynaptic actin cytoskeleton.	tmpzr1t_l9r_go_relaxed.owl	regulation of postsynaptic actin cytoskeleton remodelling							dos	2016-06-16T22:34:25Z					biological_process											owl:Class	
GO:0099159	biolink:NamedThing	regulation of modification of postsynaptic structure	Any process that modulates the frequency, rate or extent of modification of postsynaptic structure.	tmpzr1t_l9r_go_relaxed.owl	regulation of postsynapse remodelling							dos	2017-08-25T15:47:55Z					biological_process											owl:Class	
GO:1900053	biolink:NamedThing	negative regulation of retinoic acid biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of retinoic acid biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	downregulation of retinoic acid biosynthetic process|down-regulation of retinoic acid anabolic process|down regulation of retinoic acid anabolic process|inhibition of retinoic acid anabolic process|negative regulation of retinoic acid anabolic process|down-regulation of retinoic acid biosynthetic process|down regulation of retinoic acid biosynthetic process|inhibition of retinoic acid biosynthetic process|downregulation of retinoic acid anabolic process							yaf	2012-01-20T09:55:49Z					biological_process											owl:Class	
GO:0140706	biolink:NamedThing	protein-containing complex localization to centriolar satellite	A protein-containing complex localization by which the complex is transported to, or maintained in, the centriolar satellite.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/22020						pg	2021-09-01T05:59:13Z					biological_process											owl:Class	
GO:1900902	biolink:NamedThing	regulation of hexadecanal biosynthetic process	Any process that modulates the frequency, rate or extent of hexadecanal biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of hexadecanal anabolism|regulation of palmitaldehyde biosynthesis|regulation of hexadecanal formation|regulation of hexadecanal biosynthesis|regulation of palmitaldehyde biosynthetic process|regulation of hexadecanal synthesis							tt	2012-06-13T03:33:10Z					biological_process											owl:Class	
GO:1900905	biolink:NamedThing	regulation of hexadecanal metabolic process	Any process that modulates the frequency, rate or extent of hexadecanal metabolic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of hexadecanal metabolism							tt	2012-06-13T03:35:27Z					biological_process											owl:Class	
GO:0018161	biolink:NamedThing	dipyrrin biosynthetic process	The chemical reactions and pathways resulting in the formation of dipyrrins (pyrromethanes), compounds containing two pyrrole rings linked through a methine, -CH=, group.	tmpzr1t_l9r_go_relaxed.owl	dipyrrin anabolism|dipyrrin synthesis|dipyrromethane biosynthetic process|dipyrrin formation|dipyrrin biosynthesis|dipyrromethane biosynthesis													biological_process											owl:Class	
GO:0140587	biolink:NamedThing	chromatin loop anchoring activity	Bridging together two DNA loop anchors together, maintaining a chromatin loop.	tmpzr1t_l9r_go_relaxed.owl	chromosomal loop binding|DNA loop binding	https://github.com/geneontology/go-ontology/issues/20204						pg	2021-02-04T14:53:13Z					molecular_function											owl:Class	
GO:0106260	biolink:NamedThing	DNA-DNA tethering activity	Bridging together two regions of a DNA molecule.	tmpzr1t_l9r_go_relaxed.owl	dsDNA bridging|double-stranded DNA bridging	https://github.com/geneontology/go-ontology/issues/20503|https://github.com/geneontology/go-ontology/issues/19385						hjd	2020-05-07T19:53:35Z			GO:0140564		molecular_function											owl:Class	
GO:0019323	biolink:NamedThing	pentose catabolic process	The chemical reactions and pathways resulting in the breakdown of a pentose, any monosaccharide with a chain of five carbon atoms in the molecule.	tmpzr1t_l9r_go_relaxed.owl	pentose degradation|pentose catabolism|pentose breakdown													biological_process											owl:Class	
GO:0046365	biolink:NamedThing	monosaccharide catabolic process	The chemical reactions and pathways resulting in the breakdown of monosaccharides, polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms.	tmpzr1t_l9r_go_relaxed.owl	monosaccharide catabolism|monosaccharide breakdown|monosaccharide degradation													biological_process											owl:Class	
GO:1900772	biolink:NamedThing	fumitremorgin B biosynthetic process	The chemical reactions and pathways resulting in the formation of fumitremorgin B.	tmpzr1t_l9r_go_relaxed.owl	fumitremorgin B anabolism|Lanosulin biosynthetic process|Lanosulin biosynthesis|fumitremorgin B biosynthesis|Lanosulin formation|Lanosulin anabolism|fumitremorgin B formation|Lanosulin synthesis|fumitremorgin B synthesis							di	2012-06-04T09:25:50Z					biological_process											owl:Class	
GO:0005371	biolink:NamedThing	tricarboxylate secondary active transmembrane transporter activity	Enables the transfer of tricarboxylate from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters.	tmpzr1t_l9r_go_relaxed.owl	tricarboxylate carrier activity											GO:0005370		molecular_function											owl:Class	
GO:2000254	biolink:NamedThing	regulation of male germ cell proliferation	Any process that modulates the frequency, rate or extent of male germ cell proliferation.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-11-18T09:29:44Z					biological_process											owl:Class	
GO:1990832	biolink:NamedThing	slow axonal transport	The directed slow movement of non-membranous molecules in nerve cell axons. It is comprised of a Slow Component a (SCa) and a Slow Component b (SCb) which differ in transport rates and protein composition.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-08-21T17:27:32Z					biological_process											owl:Class	
GO:0060172	biolink:NamedThing	astral microtubule depolymerization	The removal of tubulin heterodimers from one or both ends of an astral microtubule. An astral microtubule is any of the spindle microtubules that radiate in all directions from the spindle poles and are thought to contribute to the forces that separate the poles and position them in relation to the rest of the cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0030953	biolink:NamedThing	astral microtubule organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of astral microtubules, any of the spindle microtubules that radiate in all directions from the spindle poles.	tmpzr1t_l9r_go_relaxed.owl	astral microtubule organisation|astral microtubule organization and biogenesis													biological_process											owl:Class	
GO:1901960	biolink:NamedThing	isobutanol metabolic process	The chemical reactions and pathways involving isobutanol.	tmpzr1t_l9r_go_relaxed.owl	isobutanol metabolism							tt	2013-02-19T21:49:44Z					biological_process											owl:Class	
GO:0086006	biolink:NamedThing	voltage-gated sodium channel activity involved in cardiac muscle cell action potential	Enables the transmembrane transfer of a sodium ion by a voltage-gated channel through the plasma membrane of a cardiac muscle cell contributing to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.	tmpzr1t_l9r_go_relaxed.owl								tb	2011-11-10T08:34:49Z					molecular_function											owl:Class	
GO:0005248	biolink:NamedThing	voltage-gated sodium channel activity	Enables the transmembrane transfer of a sodium ion by a voltage-gated channel. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.	tmpzr1t_l9r_go_relaxed.owl	voltage-dependent sodium channel activity|voltage-sensitive sodium channel|voltage-gated sodium ion channel activity|voltage gated sodium channel activity				Reactome:R-HSA-5576895									molecular_function											owl:Class	
GO:0000715	biolink:NamedThing	nucleotide-excision repair, DNA damage recognition	The identification of lesions in DNA, such as pyrimidine-dimers, intrastrand cross-links, and bulky adducts. The wide range of substrate specificity suggests the repair complex recognizes distortions in the DNA helix.	tmpzr1t_l9r_go_relaxed.owl	pyrimidine-dimer repair, DNA damage recognition													biological_process											owl:Class	
GO:1901123	biolink:NamedThing	bacitracin A catabolic process	The chemical reactions and pathways resulting in the breakdown of bacitracin A.	tmpzr1t_l9r_go_relaxed.owl	bacitracin A catabolism|bacitracin A degradation|bacitracin A breakdown							yaf	2012-07-11T03:16:20Z					biological_process											owl:Class	
GO:1901122	biolink:NamedThing	bacitracin A metabolic process	The chemical reactions and pathways involving bacitracin A.	tmpzr1t_l9r_go_relaxed.owl	bacitracin A metabolism							yaf	2012-07-11T03:15:56Z					biological_process											owl:Class	
GO:0032250	biolink:NamedThing	negative regulation of adenosine transport	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of adenosine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	down regulation of adenosine transport|inhibition of adenosine transport|down-regulation of adenosine transport|downregulation of adenosine transport													biological_process											owl:Class	
GO:0035063	biolink:NamedThing	nuclear speck organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of nuclear specks, a class of nuclear body in which splicing factors are localized.	tmpzr1t_l9r_go_relaxed.owl	nuclear speck organisation|nuclear speckle assembly|nuclear speckle organization|nuclear speck organization and biogenesis					See also the cellular component term 'nuclear speck ; GO:0016607'.								biological_process											owl:Class	
GO:0030575	biolink:NamedThing	nuclear body organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of any of the extra-nucleolar nuclear domains usually visualized by confocal microscopy and fluorescent antibodies to specific proteins.	tmpzr1t_l9r_go_relaxed.owl	nuclear body organization and biogenesis|nuclear body organisation													biological_process											owl:Class	
GO:0001920	biolink:NamedThing	negative regulation of receptor recycling	Any process that stops, prevents, or reduces the rate of receptor recycling.	tmpzr1t_l9r_go_relaxed.owl	inhibition of receptor recycling|down-regulation of receptor recycling|down regulation of receptor recycling|downregulation of receptor recycling													biological_process											owl:Class	
GO:0004877	biolink:NamedThing	complement component C3b receptor activity	Combining with the C3b product of the complement cascade and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0001847	biolink:NamedThing	opsonin receptor activity	Combining with an opsonin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0043368	biolink:NamedThing	positive T cell selection	The process of sparing immature T cells which react with self-MHC protein complexes with low affinity levels from apoptotic death.	tmpzr1t_l9r_go_relaxed.owl	positive T lymphocyte selection|positive T-lymphocyte selection|positive T-cell selection													biological_process											owl:Class	
GO:0103000	biolink:NamedThing	UDP-glucose:4-hydroxylamino-2,6-dinitrotoluene-O-glucosyltransferase activity	Catalysis of the reaction: UDP-alpha-D-glucose + 4-hydroxylamino-2,6-dinitrotoluene <=> 4-hydroxylamino-2,6-dinitrotoluene-O-glucoside + UDP + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-9748									molecular_function											owl:Class	
GO:0009123	biolink:NamedThing	nucleoside monophosphate metabolic process	The chemical reactions and pathways involving a nucleoside monophosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with phosphate on the sugar.	tmpzr1t_l9r_go_relaxed.owl	nucleoside monophosphate metabolism													biological_process											owl:Class	
GO:0010744	biolink:NamedThing	positive regulation of macrophage derived foam cell differentiation	Any process that increases the rate, frequency or extent of macrophage derived foam cell differentiation. Macrophage derived foam cell differentiation is the process in which a macrophage acquires the specialized features of a foam cell. A foam cell is a type of cell containing lipids in small vacuoles and typically seen in atherosclerotic lesions, as well as other conditions.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0009414	biolink:NamedThing	response to water deprivation	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a water deprivation stimulus, prolonged deprivation of water.	tmpzr1t_l9r_go_relaxed.owl	response to drought|drought tolerance|response to thirst|response to dehydration													biological_process											owl:Class	
GO:0014073	biolink:NamedThing	response to tropane	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tropane stimulus. Tropane is a nitrogenous bicyclic organic compound mainly known for a group of alkaloids derived from it (called tropane alkaloids), which include, among others, atropine and cocaine.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0019249	biolink:NamedThing	lactate biosynthetic process	The chemical reactions and pathways resulting in the formation of lactate, the anion of lactic acid.	tmpzr1t_l9r_go_relaxed.owl	lactate formation|lactate biosynthesis|lactate synthesis|lactate anabolism													biological_process											owl:Class	
GO:0051427	biolink:NamedThing	hormone receptor binding	Binding to a receptor for a hormone.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0051518	biolink:NamedThing	positive regulation of bipolar cell growth	Any process that activates or increases the frequency, rate or extent of bipolar cell growth, polarized growth from both ends of a cell.	tmpzr1t_l9r_go_relaxed.owl	stimulation of bipolar cell growth|up-regulation of bipolar cell growth|upregulation of bipolar cell growth|up regulation of bipolar cell growth													biological_process											owl:Class	
GO:0110003	biolink:NamedThing	regulation of tRNA C5-cytosine methylation	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving tRNA C5-cytosine methylation.	tmpzr1t_l9r_go_relaxed.owl								kmv						biological_process											owl:Class	
GO:0110002	biolink:NamedThing	regulation of tRNA methylation	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving tRNA methylation.	tmpzr1t_l9r_go_relaxed.owl								kmv						biological_process											owl:Class	
GO:0018019	biolink:NamedThing	N-terminal peptidyl-glutamine methylation	The methylation of a glutamine residue in proteins to form the peptidyl-N5-methyl-L-glutamine derivative.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0071									biological_process											owl:Class	
GO:0018199	biolink:NamedThing	peptidyl-glutamine modification	The modification of peptidyl-glutamine.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0032763	biolink:NamedThing	regulation of mast cell cytokine production	Any process that modulates the frequency, rate, or extent of mast cell cytokine production.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0000427	biolink:NamedThing	plastid-encoded plastid RNA polymerase complex	An RNA polymerase complex containing polypeptides encoded by the plastid genome. Plastid-encoded DNA-directed RNA polymerases resemble eubacterial multisubunit RNA polymerases, with a core composed of alpha, beta, and beta-prime subunits. Some forms contain multiple additional subunits. An additional sigma factor subunit is required for promoter recognition.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0000428	biolink:NamedThing	DNA-directed RNA polymerase complex	A protein complex that possesses DNA-directed RNA polymerase activity.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:2000050	biolink:NamedThing	regulation of non-canonical Wnt signaling pathway	Any process that modulates the frequency, rate or extent of non-canonical Wnt signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	regulation of non-canonical Wnt-activated signaling pathway|regulation of non-canonical Wnt receptor signaling pathway|regulation of beta-catenin-independent Wnt receptor signaling pathway|regulation of non-canonical Wnt receptor signalling pathway							jl	2010-08-20T01:04:12Z					biological_process											owl:Class	
GO:0030111	biolink:NamedThing	regulation of Wnt signaling pathway	Any process that modulates the frequency, rate or extent of the activity of the Wnt signal transduction pathway.	tmpzr1t_l9r_go_relaxed.owl	regulation of Wnt receptor signaling pathway|regulation of frizzled signalling pathway|regulation of frizzled signaling pathway|regulation of Wnt-activated signaling pathway|regulation of Wnt receptor signalling pathway											GO:0008590		biological_process											owl:Class	
GO:0036003	biolink:NamedThing	positive regulation of transcription from RNA polymerase II promoter in response to stress	Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).	tmpzr1t_l9r_go_relaxed.owl								bf	2011-09-19T03:00:18Z					biological_process											owl:Class	
GO:0033027	biolink:NamedThing	positive regulation of mast cell apoptotic process	Any process that activates or increases the frequency, rate, or extent of mast cell apoptotic process.	tmpzr1t_l9r_go_relaxed.owl	upregulation of mast cell apoptosis|up-regulation of mast cell apoptosis|up regulation of mast cell apoptosis|activation of mast cell apoptosis|stimulation of mast cell apoptosis|positive regulation of mast cell apoptosis													biological_process											owl:Class	
GO:0097331	biolink:NamedThing	response to cytarabine	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytarabine stimulus.	tmpzr1t_l9r_go_relaxed.owl								pr	2012-06-12T10:55:29Z					biological_process											owl:Class	
GO:0000824	biolink:NamedThing	inositol tetrakisphosphate 3-kinase activity	Catalysis of the reaction: ATP + 1D-myo-inositol 1,4,5,6-tetrakisphosphate = ADP + 1D-myo-inositol 1,3,4,5,6-pentakisphosphate.	tmpzr1t_l9r_go_relaxed.owl	inositol 1,4,5,6-tetrakisphosphate 3-kinase activity|inositol polyphosphate multikinase activity|EC:2.7.1.151|IpmK|1D-myo-inositol-tetrakisphosphate 3-kinase activity				Reactome:R-HSA-1855185|RHEA:11856									molecular_function											owl:Class	
GO:0051765	biolink:NamedThing	inositol tetrakisphosphate kinase activity	Catalysis of the reaction: inositol tetrakisphosphate + ATP = inositol pentakisphosphate + ADP.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0039015	biolink:NamedThing	cell proliferation involved in pronephros development	The multiplication or reproduction of cells, resulting in the expansion of the population in the pronephros.	tmpzr1t_l9r_go_relaxed.owl	cell proliferation involved in pronephric kidney development							bf	2010-07-02T10:01:49Z					biological_process											owl:Class	
GO:1904393	biolink:NamedThing	regulation of skeletal muscle acetylcholine-gated channel clustering	Any process that modulates the frequency, rate or extent of skeletal muscle acetylcholine-gated channel clustering.	tmpzr1t_l9r_go_relaxed.owl	regulation of skeletal muscle nicotinic acetylcholine receptor clustering|regulation of skeletal muscle AChR clustering							sl	2015-06-23T19:23:25Z					biological_process											owl:Class	
GO:1903909	biolink:NamedThing	regulation of receptor clustering	Any process that modulates the frequency, rate or extent of receptor clustering.	tmpzr1t_l9r_go_relaxed.owl								als	2015-02-09T10:56:33Z					biological_process											owl:Class	
GO:0032755	biolink:NamedThing	positive regulation of interleukin-6 production	Any process that activates or increases the frequency, rate, or extent of interleukin-6 production.	tmpzr1t_l9r_go_relaxed.owl	stimulation of interleukin-6 production|up regulation of interleukin-6 production|positive regulation of interleukin-6 biosynthetic process|positive regulation of interleukin-6 secretion|upregulation of interleukin-6 production|positive regulation of IL-6 production|up-regulation of interleukin-6 production|activation of interleukin-6 production											GO:0045410|GO:2000778		biological_process											owl:Class	
GO:0010727	biolink:NamedThing	negative regulation of hydrogen peroxide metabolic process	Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving hydrogen peroxide.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of hydrogen peroxide metabolism													biological_process											owl:Class	
GO:2000378	biolink:NamedThing	negative regulation of reactive oxygen species metabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of reactive oxygen species metabolic process.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of reactive oxygen species metabolism|negative regulation of ROS metabolic process							mah	2011-02-11T02:06:49Z					biological_process											owl:Class	
GO:0002228	biolink:NamedThing	natural killer cell mediated immunity	The promotion of an immune response by natural killer cells through direct recognition of target cells or through the release of cytokines.	tmpzr1t_l9r_go_relaxed.owl	NK cell mediated immunity													biological_process											owl:Class	
GO:0035645	biolink:NamedThing	enteric smooth muscle cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell of the intestine.	tmpzr1t_l9r_go_relaxed.owl	intestinal smooth muscle cell differentiation							bf	2011-01-21T02:58:58Z					biological_process											owl:Class	
GO:0051145	biolink:NamedThing	smooth muscle cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell; smooth muscle lacks transverse striations in its constituent fibers and are almost always involuntary.	tmpzr1t_l9r_go_relaxed.owl	nonstriated muscle cell differentiation													biological_process											owl:Class	
GO:0048316	biolink:NamedThing	seed development	The process whose specific outcome is the progression of the seed over time, from its formation to the mature structure. A seed is a propagating organ formed in the sexual reproductive cycle of gymnosperms and angiosperms, consisting of a protective coat enclosing an embryo and food reserves.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0046607	biolink:NamedThing	positive regulation of centrosome cycle	Any process that activates or increases the frequency, rate or extent of the centrosome cycle.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of centrosome cycle|upregulation of centrosome cycle|up regulation of centrosome cycle|activation of centrosome cycle|stimulation of centrosome cycle													biological_process											owl:Class	
GO:0070089	biolink:NamedThing	chloride-activated potassium channel activity	Enables the chloride concentration-regulatable energy-independent passage of potassium ions across a lipid bilayer down a concentration gradient.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0005267	biolink:NamedThing	potassium channel activity	Enables the facilitated diffusion of a potassium ion (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-1299297|Reactome:R-HSA-1299359|Reactome:R-HSA-5578910|Reactome:R-HSA-1296037|Reactome:R-HSA-1299304|Reactome:R-HSA-1296024|Reactome:R-HSA-1299318|Reactome:R-HSA-1296039|Reactome:R-HSA-1299338|Reactome:R-HSA-1296035|Reactome:R-HSA-1296348|Reactome:R-HSA-2534365									molecular_function											owl:Class	
GO:1900928	biolink:NamedThing	positive regulation of L-threonine import across plasma membrane	Any process that activates or increases the frequency, rate or extent of L-threonine import into cell.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of L-threonine import|positive regulation of L-threonine uptake|up-regulation of L-threonine import|up regulation of L-threonine uptake|upregulation of L-threonine import|up regulation of L-threonine import|activation of L-threonine import|upregulation of L-threonine uptake|activation of L-threonine uptake|up-regulation of L-threonine uptake							al	2012-06-13T07:42:00Z					biological_process											owl:Class	
GO:1900926	biolink:NamedThing	regulation of L-threonine import across plasma membrane	Any process that modulates the frequency, rate or extent of L-threonine import into cell.	tmpzr1t_l9r_go_relaxed.owl	regulation of L-threonine uptake|regulation of L-threonine import							al	2012-06-13T07:41:32Z					biological_process											owl:Class	
GO:0050778	biolink:NamedThing	positive regulation of immune response	Any process that activates or increases the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.	tmpzr1t_l9r_go_relaxed.owl	stimulation of immune response|up regulation of immune response|upregulation of immune response|up-regulation of immune response													biological_process											owl:Class	
GO:0060692	biolink:NamedThing	mesenchymal cell differentiation involved in salivary gland development	The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal cell of the salivary gland. A mesenchymal cell is a loosely associated cell that is part of the connective tissue in an organism. Mesenchymal cells give rise to more mature connective tissue cell types.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-06-08T01:08:44Z					biological_process											owl:Class	
GO:0060689	biolink:NamedThing	cell differentiation involved in salivary gland development	The process in which a relatively unspecialized cell acquires specialized structural and/or functional features that characterize the cells of the salivary gland.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-06-08T01:01:35Z					biological_process											owl:Class	
GO:0072007	biolink:NamedThing	mesangial cell differentiation	The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesangial cells of the kidney as it progresses from its formation to the mature state.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-01-25T01:59:09Z					biological_process											owl:Class	
GO:0072153	biolink:NamedThing	renal interstitial fibroblast fate commitment	The process in which the developmental fate of a cell becomes restricted such that it will develop into a renal fibroblast.	tmpzr1t_l9r_go_relaxed.owl	kidney interstitial cell fate commitment							mah	2010-02-24T02:16:53Z					biological_process											owl:Class	
GO:0102283	biolink:NamedThing	3-ketodihydrosphinganine (C20) reductase activity	Catalysis of the reaction: C20 sphinganine(1+) + NADP <=> C20 3-dehydrosphinganine(1+) + NADPH + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-12642									molecular_function											owl:Class	
GO:1905152	biolink:NamedThing	positive regulation of voltage-gated sodium channel activity	Any process that activates or increases the frequency, rate or extent of voltage-gated sodium channel activity.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of voltage-dependent sodium channel activity|upregulation of voltage-dependent sodium channel activity|upregulation of voltage gated sodium channel activity|activation of voltage-gated sodium channel activity|activation of voltage gated sodium channel activity|positive regulation of voltage gated sodium channel activity|activation of voltage-gated sodium ion channel activity|positive regulation of voltage-dependent sodium channel activity|activation of voltage-sensitive sodium channel|up regulation of voltage-gated sodium channel activity|up regulation of voltage-sensitive sodium channel|up-regulation of voltage-gated sodium ion channel activity|upregulation of voltage-gated sodium channel activity|upregulation of voltage-sensitive sodium channel|up regulation of voltage-gated sodium ion channel activity|up regulation of voltage gated sodium channel activity|positive regulation of voltage-gated sodium ion channel activity|activation of voltage-dependent sodium channel activity|up-regulation of voltage gated sodium channel activity|up-regulation of voltage-sensitive sodium channel|up regulation of voltage-dependent sodium channel activity|upregulation of voltage-gated sodium ion channel activity|positive regulation of voltage-sensitive sodium channel|up-regulation of voltage-gated sodium channel activity							sl	2016-04-15T21:47:57Z					biological_process											owl:Class	
GO:2000651	biolink:NamedThing	positive regulation of sodium ion transmembrane transporter activity	Any process that activates or increases the frequency, rate or extent of sodium ion transmembrane transporter activity.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of sodium transporter activity							yaf	2011-04-28T08:43:00Z					biological_process											owl:Class	
GO:0072744	biolink:NamedThing	cellular response to trichodermin	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a trichodermin stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2012-08-31T12:29:38Z					biological_process											owl:Class	
GO:0071362	biolink:NamedThing	cellular response to ether	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ether stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-12-11T03:03:22Z					biological_process											owl:Class	
GO:0051575	biolink:NamedThing	5'-deoxyribose-5-phosphate lyase activity	Catalysis of the beta-elimination of the 5' deoxyribose-5-phosphate at an abasic site in DNA where a DNA-(apurinic or apyrimidinic site) lyase has already cleaved the C-O-P bond 3' to the apurinic or apyrimidinic site.	tmpzr1t_l9r_go_relaxed.owl	dRP lyase activity|5'-deoxyribose phosphate activity|dRPase activity													molecular_function											owl:Class	
GO:0070623	biolink:NamedThing	regulation of thiamine biosynthetic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of thiamine.	tmpzr1t_l9r_go_relaxed.owl	regulation of thiamine biosynthesis|regulation of thiamine anabolism|regulation of thiamine synthesis|regulation of thiamine formation|regulation of thiamin biosynthetic process							mah	2009-05-01T03:15:49Z					biological_process											owl:Class	
GO:0042942	biolink:NamedThing	D-serine transport	The directed movement of D-serine, the D-enantiomer of 2-amino-3-hydroxypropanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0042940	biolink:NamedThing	D-amino acid transport	The directed movement of the D-enantiomer of an amino acid into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1903314	biolink:NamedThing	regulation of nitrogen cycle metabolic process	Any process that modulates the frequency, rate or extent of nitrogen cycle metabolic process.	tmpzr1t_l9r_go_relaxed.owl								vw	2014-08-18T12:57:34Z					biological_process											owl:Class	
GO:0034129	biolink:NamedThing	positive regulation of MyD88-independent toll-like receptor signaling pathway	Any process that activates or increases the frequency, rate, or extent of MyD88-independent toll-like receptor signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of MyD88-independent toll-like receptor signalling pathway|positive regulation of MyD88-independent TLR signaling pathway|positive regulation of MyD88-independent toll-like receptor													biological_process											owl:Class	
GO:0030762	biolink:NamedThing	tetrahydrocolumbamine 2-O-methyltransferase activity	Catalysis of the reaction: (S)-tetrahydrocolumbamine + S-adenosyl-L-methionine(1+) = S-adenosyl-L-homocysteine + H(+) + tetrahydropalmatine.	tmpzr1t_l9r_go_relaxed.owl	S-adenosyl-L-methionine:5,8,13,13a-tetrahydrocolumbamine 2-O-methyltransferase activity|tetrahydrocolumbamine methyltransferase activity				EC:2.1.1.89|KEGG_REACTION:R04077|MetaCyc:2.1.1.89-RXN|RHEA:22536									molecular_function											owl:Class	
GO:0030062	biolink:NamedThing	mitochondrial tricarboxylic acid cycle enzyme complex	Any of the heteromeric enzymes, located in the mitochondrion, that act in the tricarboxylic acid (TCA) cycle.	tmpzr1t_l9r_go_relaxed.owl	TCA cycle enzyme complex													cellular_component											owl:Class	
GO:0045239	biolink:NamedThing	tricarboxylic acid cycle enzyme complex	Any of the heteromeric enzymes that act in the TCA cycle.	tmpzr1t_l9r_go_relaxed.owl	TCA cycle enzyme complex													cellular_component											owl:Class	
GO:0015116	biolink:NamedThing	sulfate transmembrane transporter activity	Enables the transfer of sulfate ions, SO4(2-), from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	sulfate permease activity|sulphate transporter activity				RHEA:34983|Reactome:R-HSA-3560789|Reactome:R-HSA-427555|Reactome:R-HSA-8875871									molecular_function											owl:Class	
GO:0044018	biolink:NamedThing	histone acetyltransferase activity (H3-K36 specific)	Catalysis of the reaction: acetyl-CoA + histone H3 L-lysine (position 36) = CoA + histone H3 N6-acetyl-L-lysine (position 36).	tmpzr1t_l9r_go_relaxed.owl	histone lysine N-acetyltransferase activity (H3-K36 specific)													molecular_function											owl:Class	
GO:0010484	biolink:NamedThing	H3 histone acetyltransferase activity	Catalysis of the reaction: acetyl-CoA + histone H3 = CoA + acetyl-histone H3.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0046597	biolink:NamedThing	negative regulation of viral entry into host cell	Any process that stops, prevents, or reduces the frequency, rate or extent of the entry of viral entry into a host cell.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of viral penetration into host cell													biological_process											owl:Class	
GO:1901059	biolink:NamedThing	p-hydroxyphenyl lignin catabolic process	The chemical reactions and pathways resulting in the breakdown of p-hydroxyphenyl lignin.	tmpzr1t_l9r_go_relaxed.owl	p-hydroxyphenyl lignin catabolism|p-hydroxyphenyl lignin breakdown|H-lignin catabolic process|p-hydroxyphenyl lignin degradation							tt	2012-06-29T12:32:17Z					biological_process											owl:Class	
GO:0033245	biolink:NamedThing	negative regulation of penicillin metabolic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving any antibiotic that contains the condensed beta-lactamthiazolidine ring system.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of penicillin metabolism													biological_process											owl:Class	
GO:0002578	biolink:NamedThing	negative regulation of antigen processing and presentation	Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation.	tmpzr1t_l9r_go_relaxed.owl	down regulation of antigen processing and presentation|down-regulation of antigen processing and presentation|downregulation of antigen processing and presentation|inhibition of antigen processing and presentation													biological_process											owl:Class	
GO:0001760	biolink:NamedThing	aminocarboxymuconate-semialdehyde decarboxylase activity	Catalysis of the reaction: 2-amino-3-carboxymuconate 6-semialdehyde + H(+) = 2-aminomuconate 6-semialdehyde + CO(2).	tmpzr1t_l9r_go_relaxed.owl	alpha-amino-beta-carboxymuconate-epsilon-semialdehyde beta-decarboxylase activity|picolinic acid carboxylase activity|alpha-amino-beta-carboxymuconate-epsilon-semialdehade decarboxylase activity|picolinic acid decarboxylase activity|2-amino-3-(3-oxoprop-1-en-1-yl)but-2-enedioate carboxy-lyase (2-aminomuconate-semialdehyde-forming)|2-amino-3-(3-oxoprop-2-enyl)but-2-enedioate carboxy-lyase activity|2-amino-3-(3-oxoprop-1-en-1-yl)but-2-enedioate carboxy-lyase activity|ACMSD activity				MetaCyc:AMINO-CARBOXYMUCONATE-SEMIALDEHYDE-RXN|EC:4.1.1.45|KEGG_REACTION:R04323|RHEA:16557									molecular_function											owl:Class	
GO:1901962	biolink:NamedThing	S-adenosyl-L-methionine transmembrane transport	The directed movement of S-adenosyl-L-methionine across a membrane.	tmpzr1t_l9r_go_relaxed.owl	SAM transmembrane transport|S-adenosylmethionine transmembrane transport							jl	2013-02-20T14:45:08Z					biological_process											owl:Class	
GO:0015805	biolink:NamedThing	S-adenosyl-L-methionine transport	The directed movement of S-adenosylmethionine, S-(5'-adenosyl)-L-methionine, an important intermediate in one-carbon metabolism, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	SAM transport|S-adenosylmethionine transport|S-adenosyl methionine transport													biological_process											owl:Class	
GO:0051320	biolink:NamedThing	S phase	The cell cycle phase, following G1, during which DNA synthesis takes place.	tmpzr1t_l9r_go_relaxed.owl	S-phase				Wikipedia:S_phase	Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).								biological_process											owl:Class	
GO:1902215	biolink:NamedThing	negative regulation of interleukin-4-mediated signaling pathway	Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-4-mediated signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	downregulation of interleukin-4-mediated signalling pathway|downregulation of interleukin-4-mediated signaling pathway|down regulation of interleukin-4-mediated signalling pathway|negative regulation of IL-4-mediated signaling pathway|inhibition of IL-4-mediated signaling pathway|down-regulation of interleukin-4-mediated signalling pathway|negative regulation of interleukin-4-mediated signalling pathway|down regulation of interleukin-4-mediated signaling pathway|inhibition of interleukin-4-mediated signalling pathway|inhibition of interleukin-4-mediated signaling pathway|down-regulation of IL-4-mediated signaling pathway|down-regulation of interleukin-4-mediated signaling pathway|down regulation of IL-4-mediated signaling pathway|downregulation of IL-4-mediated signaling pathway							lb	2013-06-12T12:53:14Z					biological_process											owl:Class	
GO:0014049	biolink:NamedThing	positive regulation of glutamate secretion	Any process that activates or increases the frequency, rate or extent of the controlled release of glutamate.	tmpzr1t_l9r_go_relaxed.owl	up regulation of glutamate secretion|upregulation of glutamate secretion|activation of glutamate secretion|stimulation of glutamate secretion|up-regulation of glutamate secretion													biological_process											owl:Class	
GO:0050493	biolink:NamedThing	GPI anchor biosynthetic process via N-threonyl-glycosylphosphatidylinositolethanolamine	The chemical reactions and pathways resulting in the formation of a C-terminal peptidyl-threonyl ethanolamide-linked glycosylphosphatidylinositol (GPI) anchor following hydrolysis of a threonyl-peptide bond in the carboxy-terminal region of a membrane-associated protein.	tmpzr1t_l9r_go_relaxed.owl	GPI anchor synthesis via N-threonyl-glycosylphosphatidylinositolethanolamine|GPI anchor anabolism via N-threonyl-glycosylphosphatidylinositolethanolamine|GPI anchor formation via N-threonyl-glycosylphosphatidylinositolethanolamine				RESID:AA0164									biological_process											owl:Class	
GO:0006506	biolink:NamedThing	GPI anchor biosynthetic process	The chemical reactions and pathways resulting in the formation of a glycosylphosphatidylinositol (GPI) anchor that attaches some membrane proteins to the lipid bilayer of the cell membrane. The phosphatidylinositol group is linked via the C-6 hydroxyl residue of inositol to a carbohydrate chain which is itself linked to the protein via an ethanolamine phosphate group, its amino group forming an amide linkage with the C-terminal carboxyl of the protein. Some GPI anchors have variants on this canonical linkage.	tmpzr1t_l9r_go_relaxed.owl	glycosylphosphatidylinositol biosynthetic process|GPI anchor synthesis|GPI anchor formation|GPI anchor anabolism|GPI anchor biosynthesis|glycosylphosphatidylinositol biosynthesis|GPI/GSI anchor biosynthesis|GPI/GSI anchor biosynthetic process											GO:0015998		biological_process											owl:Class	
GO:0006534	biolink:NamedThing	cysteine metabolic process	The chemical reactions and pathways involving cysteine, 2-amino-3-mercaptopropanoic acid.	tmpzr1t_l9r_go_relaxed.owl	cysteine metabolism				Wikipedia:Cysteine_metabolism									biological_process											owl:Class	
GO:0048246	biolink:NamedThing	macrophage chemotaxis	The movement of a macrophage in response to an external stimulus.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1905517	biolink:NamedThing	macrophage migration	The orderly movement of a macrophage from one site to another.	tmpzr1t_l9r_go_relaxed.owl								sl	2016-09-30T22:17:45Z					biological_process											owl:Class	
GO:1990809	biolink:NamedThing	endoplasmic reticulum tubular network membrane organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endoplasmic reticulum (ER) tubular network membrane.	tmpzr1t_l9r_go_relaxed.owl								vw	2015-07-22T16:42:36Z					biological_process											owl:Class	
GO:0090158	biolink:NamedThing	endoplasmic reticulum membrane organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an endoplasmic reticulum membrane.	tmpzr1t_l9r_go_relaxed.owl	endoplasmic reticulum membrane organisation							tb	2009-12-08T08:27:17Z					biological_process											owl:Class	
GO:2000626	biolink:NamedThing	negative regulation of miRNA catabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of miRNA catabolic process.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of microRNA catabolic process							dph	2011-04-18T03:46:39Z					biological_process											owl:Class	
GO:0042263	biolink:NamedThing	neuropeptide F receptor activity	Combining with neuropeptide F and transmitting the signal within the cell to initiate a change in cell activity. Neuropeptide F is an arthropod peptide of more than 28 residues (typically 28-45) with a consensus C-terminal RxRFamide (commonly RPRFa, but also RVRFa.	tmpzr1t_l9r_go_relaxed.owl	NPF receptor activity					Despite their naming, neuropeptide F (NPF) and short neuropeptide F (sNPF) are not closely related.								molecular_function											owl:Class	
GO:0002050	biolink:NamedThing	pyoverdine catabolic process	The chemical reactions and pathways resulting in the breakdown of the siderochrome pyoverdine.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0046215	biolink:NamedThing	siderophore catabolic process	The chemical reactions and pathways resulting in the breakdown of siderophores, low molecular weight Fe(III)-chelating substances made by aerobic or facultatively anaerobic bacteria, especially when growing under iron deficient conditions. The complexes of Fe(3+)-siderophores have very high stability constants and are taken up by specific transport systems by microorganisms; the subsequent release of iron requires enzymatic action.	tmpzr1t_l9r_go_relaxed.owl	siderophore catabolism|siderophore degradation|siderophore breakdown|siderochrome catabolism													biological_process											owl:Class	
GO:0033129	biolink:NamedThing	positive regulation of histone phosphorylation	Any process that activates or increases the frequency, rate or extent of the addition of one or more phosphate groups to a histone protein.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0033127	biolink:NamedThing	regulation of histone phosphorylation	Any process that modulates the frequency, rate or extent of the addition of one or more phosphate groups to a histone protein.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0071238	biolink:NamedThing	cellular response to brefeldin A	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a brefeldin A stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-12-03T02:25:52Z					biological_process											owl:Class	
GO:1900230	biolink:NamedThing	positive regulation of single-species biofilm formation in or on host organism	Any process that activates or increases the frequency, rate or extent of single-species biofilm formation in or on host organism.	tmpzr1t_l9r_go_relaxed.owl	activation of single-species biofilm formation in or on host organism|up regulation of single-species biofilm formation in or on host organism|upregulation of single-species biofilm formation in or on host organism|up-regulation of single-species biofilm formation in or on host organism							di	2012-03-23T04:37:14Z					biological_process											owl:Class	
GO:0090230	biolink:NamedThing	regulation of centromere complex assembly	Any process that modulates the rate, frequency, or extent of centromere complex assembly, the aggregation, arrangement and bonding together of proteins and centromeric DNA molecules to form a centromeric protein-DNA complex.	tmpzr1t_l9r_go_relaxed.owl	centromere licensing							tb	2010-01-20T10:20:49Z					biological_process											owl:Class	
GO:0017076	biolink:NamedThing	purine nucleotide binding	Binding to a purine nucleotide, a compound consisting of a purine nucleoside esterified with (ortho)phosphate.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:2000039	biolink:NamedThing	regulation of trichome morphogenesis	Any process that modulates the frequency, rate or extent of trichome morphogenesis.	tmpzr1t_l9r_go_relaxed.owl	regulation of trichome cell morphogenesis during differentiation							tb	2010-08-05T11:36:31Z					biological_process											owl:Class	
GO:2000024	biolink:NamedThing	regulation of leaf development	Any process that modulates the frequency, rate or extent of leaf development.	tmpzr1t_l9r_go_relaxed.owl								tb	2010-08-05T11:25:14Z					biological_process											owl:Class	
GO:0038043	biolink:NamedThing	interleukin-5-mediated signaling pathway	A series of molecular signals initiated by the binding of interleukin-5 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.	tmpzr1t_l9r_go_relaxed.owl	IL-5-mediated signaling pathway|interleukin-5-mediated signalling pathway							bf	2011-11-03T04:18:21Z					biological_process											owl:Class	
GO:0071524	biolink:NamedThing	pyrrolysine biosynthetic process	The chemical reactions and pathways resulting in the formation of pyrrolysine, N6-{[(2R,3R)-3-methyl-3,4-dihydro-2H-pyrrol-2-yl]carbonyl}-L-lysine.	tmpzr1t_l9r_go_relaxed.owl	pyrrolysine synthesis|pyrrolysine biosynthesis|monomethylamine methyltransferase cofactor lysine adduct biosynthetic process|pyrrolysine anabolism|pyrrolysine formation							mah	2010-01-07T02:40:24Z					biological_process											owl:Class	
GO:0051666	biolink:NamedThing	actin cortical patch localization	Any process in which actin cortical patches are transported to, or maintained in, a specific location. An actin cortical patch is a discrete actin-containing structure found just beneath the plasma membrane in fungal cells.	tmpzr1t_l9r_go_relaxed.owl	establishment and maintenance of actin cortical patch localization|actin cortical patch localisation													biological_process											owl:Class	
GO:0106290	biolink:NamedThing	trans-cinnamate-CoA ligase activity	Catalysis of the reaction: (E)-cinnamate + ATP + CoA = (E)-cinnamoyl-CoA + AMP + diphosphate.	tmpzr1t_l9r_go_relaxed.owl					RHEA:64788			hjd	2020-08-18T16:53:10Z					molecular_function											owl:Class	
GO:0060584	biolink:NamedThing	regulation of prostaglandin-endoperoxide synthase activity	Any process that modulates the rate, frequency or prostaglandin-endoperoxide synthase activity. Prostaglandin-endoperoxide synthase activity is the catalysis of the reaction: arachidonate + donor-H2 + 2 O2 = prostaglandin H2 + acceptor + H2O.	tmpzr1t_l9r_go_relaxed.owl	regulation of prostaglandin synthetase activity|regulation of fatty acid cyclooxygenase activity|regulation of (PG)H synthase activity|regulation of PG synthetase activity							dph	2009-05-08T02:08:37Z					biological_process											owl:Class	
GO:0006019	biolink:NamedThing	deoxyribose 5-phosphate phosphorylation	The process of introducing a phosphate group into deoxyribose 5-phosphate to produce deoxyribose bisphosphate.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0016310	biolink:NamedThing	phosphorylation	The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Phosphorylation									biological_process											owl:Class	
GO:0032035	biolink:NamedThing	myosin II tail binding	Binding to the tail region of a myosin II heavy chain.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0032038	biolink:NamedThing	myosin II heavy chain binding	Binding to a heavy chain of a myosin II complex.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0014887	biolink:NamedThing	cardiac muscle adaptation	The process in which cardiac muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors.	tmpzr1t_l9r_go_relaxed.owl	cardiac muscle plasticity													biological_process											owl:Class	
GO:0014888	biolink:NamedThing	striated muscle adaptation	Any process in which striated muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. These adaptive events occur in both muscle fibers and associated structures (motoneurons and capillaries), and they involve alterations in regulatory mechanisms, contractile properties and metabolic capacities.	tmpzr1t_l9r_go_relaxed.owl	striated muscle plasticity													biological_process											owl:Class	
GO:0062063	biolink:NamedThing	BBSome binding	Binding to a BBSome complex.	tmpzr1t_l9r_go_relaxed.owl								dph	2018-08-31T13:59:18Z					molecular_function											owl:Class	
GO:0046508	biolink:NamedThing	hydrolase activity, acting on carbon-sulfur bonds	Catalysis of the hydrolysis of any carbon-sulfur bond, C-S.	tmpzr1t_l9r_go_relaxed.owl	hydrolase activity, acting on carbon-sulphur bonds				EC:3.13.-.-									molecular_function											owl:Class	
GO:0006346	biolink:NamedThing	DNA methylation-dependent heterochromatin assembly	Repression of transcription by methylation of DNA, leading to the formation of heterochromatin.	tmpzr1t_l9r_go_relaxed.owl	methylation-dependent heterochromatic silencing|methylation-dependent chromatin silencing	https://github.com/geneontology/go-ontology/issues/22047												biological_process											owl:Class	
GO:0031507	biolink:NamedThing	heterochromatin assembly	An epigenetic gene silencing mechanism that involves the assembly of chromatin into heterochromatin, resulting in a chromatin conformation refractory to transcription. This process starts with heterochromatin nucleation, its spreading, and ends with heterochromatin boundary formation.	tmpzr1t_l9r_go_relaxed.owl	chromatin silencing|heterochromatin formation involved in chromatin silencing|establishment of heterochromatin architecture|heterochromatin formation involved in chromatin silencing at centromere outer repeat region|heterochromatin assembly involved in chromatin silencing|heterochromatin formation|heterochromatin assembly involved in chromatin silencing at pericentric region|heterochromatic silencing|establishment of heterochromatic silencing|heterochromatin maintenance|transcriptional gene silencing|heterochromatin assembly involved in chromatin silencing at centromere outer repeat region|establishment of heterochromatin architecture involved in chromatin silencing at pericentric region|establishment of chromatin silencing|chromatin-mediated silencing|establishment of heterochromatin architecture involved in chromatin silencing at centromere outer repeat region|TGS|heterochromatin formation involved in chromatin silencing at pericentric region	https://github.com/geneontology/go-ontology/issues/22030|https://github.com/geneontology/go-ontology/issues/19112|https://github.com/geneontology/go-ontology/issues/18954										GO:0006343|GO:0006342|GO:1904497|GO:0070869|GO:0016440		biological_process											owl:Class	
GO:0071397	biolink:NamedThing	cellular response to cholesterol	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cholesterol stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-12-11T04:39:31Z					biological_process											owl:Class	
GO:1900909	biolink:NamedThing	negative regulation of olefin metabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of olefin metabolic process.	tmpzr1t_l9r_go_relaxed.owl	inhibition of olefin metabolism|down-regulation of olefin metabolism|down regulation of olefin metabolism|downregulation of olefin metabolism|downregulation of olefin metabolic process|down-regulation of olefin metabolic process|down regulation of olefin metabolic process|negative regulation of olefin metabolism|inhibition of olefin metabolic process							tt	2012-06-13T04:18:50Z					biological_process											owl:Class	
GO:0019609	biolink:NamedThing	3-hydroxyphenylacetate metabolic process	The chemical reactions and pathways involving 3-hydroxyphenylacetate, 1,3-benzenediol monoacetate, also known as resorcinol monoacetate.	tmpzr1t_l9r_go_relaxed.owl	3HPA metabolic process|3HPA metabolism|3-hydroxyphenylacetate metabolism													biological_process											owl:Class	
GO:0044396	biolink:NamedThing	actin cortical patch organization	A process that is carried out at the cellular level and results in the assembly, arrangement of constituent parts, or disassembly of an actin cortical patch, a discrete actin-containing structure found at the plasma membrane in cells, at sites of endocytosis.	tmpzr1t_l9r_go_relaxed.owl	actin cortical patch organisation							jl	2011-12-21T03:33:25Z					biological_process											owl:Class	
GO:0030210	biolink:NamedThing	heparin biosynthetic process	The chemical reactions and pathways resulting in the formation of heparin, any member of a group of glycosaminoglycans of average Mr (6000-20000), consisting predominantly of alternating alpha-(1->4)-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues.	tmpzr1t_l9r_go_relaxed.owl	heparin anabolism|heparin formation|heparan sulfate biosynthetic process|heparin synthesis|heparin biosynthesis													biological_process											owl:Class	
GO:0050159	biolink:NamedThing	orsellinate decarboxylase activity	Catalysis of the reaction: o-orsellinate + H(+) = CO(2) + orcinol.	tmpzr1t_l9r_go_relaxed.owl	orsellinate carboxy-lyase (orcinol-forming)|orsellinate carboxy-lyase activity				KEGG_REACTION:R02831|EC:4.1.1.58|RHEA:16733|MetaCyc:ORSELLINATE-DECARBOXYLASE-RXN									molecular_function											owl:Class	
GO:0001804	biolink:NamedThing	negative regulation of type III hypersensitivity	Any process that stops, prevents, or reduces the rate of type III hypersensitivity, a type of inflammatory response.	tmpzr1t_l9r_go_relaxed.owl	downregulation of type III hypersensitivity|down-regulation of type III hypersensitivity|inhibition of type III hypersensitivity|down regulation of type III hypersensitivity													biological_process											owl:Class	
GO:0002887	biolink:NamedThing	negative regulation of myeloid leukocyte mediated immunity	Any process that stops, prevents, or reduces the frequency, rate, or extent of myeloid leukocyte mediated immunity.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of myeloid leukocyte mediated immunity|downregulation of myeloid leukocyte mediated immunity|inhibition of myeloid leukocyte mediated immunity|down regulation of myeloid leukocyte mediated immunity													biological_process											owl:Class	
GO:0061003	biolink:NamedThing	positive regulation of dendritic spine morphogenesis	Any process that increases the rate, frequency, or extent of dendritic spine morphogenesis, the process in which the anatomical structures of a dendritic spine are generated and organized. A dendritic spine is a protrusion from a dendrite and a specialized subcellular compartment involved in synaptic transmission.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-01-20T09:36:54Z					biological_process											owl:Class	
GO:0050775	biolink:NamedThing	positive regulation of dendrite morphogenesis	Any process that activates or increases the frequency, rate or extent of dendrite morphogenesis.	tmpzr1t_l9r_go_relaxed.owl	up regulation of dendrite morphogenesis|stimulation of dendrite morphogenesis|activation of dendrite morphogenesis|up-regulation of dendrite morphogenesis|upregulation of dendrite morphogenesis													biological_process											owl:Class	
GO:1901247	biolink:NamedThing	negative regulation of lung ciliated cell differentiation	Any process that stops, prevents or reduces the frequency, rate or extent of lung ciliated cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	downregulation of lung ciliated cell differentiation|inhibition of lung ciliated cell differentiation|down regulation of lung ciliated cell differentiation|down-regulation of lung ciliated cell differentiation							vk	2012-08-08T08:58:58Z					biological_process											owl:Class	
GO:0019573	biolink:NamedThing	D-arabinose catabolic process to xylulose 5-phosphate	The chemical reactions and pathways resulting in the breakdown of D-arabinose to form xylulose 5-phosphate. D-arabinose is converted into D-ribulose, which is phosphorylated to ribulose-5-phosphate, which is isomerized to give D-xylulose-5-phosphate.	tmpzr1t_l9r_go_relaxed.owl	D-arabinose breakdown to xylulose 5-phosphate|D-arabinose degradation to xylulose 5-phosphate				MetaCyc:DARABCAT-PWY									biological_process											owl:Class	
GO:0019571	biolink:NamedThing	D-arabinose catabolic process	The chemical reactions and pathways resulting in the breakdown of D-arabinose, the D-enantiomer of arabino-pentose.	tmpzr1t_l9r_go_relaxed.owl	D-arabinose degradation|D-arabinose catabolism|D-arabinose breakdown													biological_process											owl:Class	
GO:0018052	biolink:NamedThing	C-terminal peptidyl-tyrosine amidation	The formation of a C-terminal peptidyl-tyrosine amide by hydrolysis and oxidation of an interior Tyr-Gly peptide in a secreted protein.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0099									biological_process											owl:Class	
GO:0030077	biolink:NamedThing	plasma membrane light-harvesting complex	A plasma membrane protein-pigment complex that may be closely or peripherally associated to photosynthetic reaction centers that participate in harvesting and transferring radiant energy to the reaction center. Examples of this complex are found in bacterial species.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0030076	biolink:NamedThing	light-harvesting complex	A protein-pigment complex that may be closely or peripherally associated to photosynthetic reaction centers that participate in harvesting and transferring radiant energy to the reaction center.	tmpzr1t_l9r_go_relaxed.owl	antenna complex				Wikipedia:Light-harvesting_complex									cellular_component											owl:Class	
GO:0106365	biolink:NamedThing	beta-carotene isomerase activity	Catalyzes the reaction: all-trans-beta-carotene = 9-cis-beta-carotene.	tmpzr1t_l9r_go_relaxed.owl					EC:5.2.1.14|RHEA:34455			hjd	2021-02-16T15:32:24Z					molecular_function											owl:Class	
GO:1900844	biolink:NamedThing	negative regulation of monodictyphenone biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of monodictyphenone biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	downregulation of monodictyphenone biosynthetic process|down regulation of monodictyphenone biosynthetic process|down-regulation of monodictyphenone biosynthetic process							di	2012-06-07T09:41:00Z					biological_process											owl:Class	
GO:0043260	biolink:NamedThing	laminin-11 complex	A laminin complex composed of alpha5, beta2 and gamma1 polypeptide chains.	tmpzr1t_l9r_go_relaxed.owl	laminin-521 complex													cellular_component											owl:Class	
GO:0043256	biolink:NamedThing	laminin complex	A large, extracellular glycoprotein complex composed of three different polypeptide chains, alpha, beta and gamma. Provides an integral part of the structural scaffolding of basement membranes.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0036512	biolink:NamedThing	trimming of second mannose on A branch	The removal of the second alpha-1,2-linked mannose from the A-chain of a glycoprotein oligosaccharide in the endoplasmic reticulum.	tmpzr1t_l9r_go_relaxed.owl	conversion of (Man)8A(GlcNAc)2 to (Man)7AA(GlcNAc)2|glycoprotein mannose trimming on A branch|conversion of M8A to M7AA					Consider also annotating to 'mannosyl-oligosaccharide 1,2-alpha-mannosidase activity ; GO:0004571'.		bf	2015-06-11T14:16:40Z					biological_process											owl:Class	
GO:1904380	biolink:NamedThing	endoplasmic reticulum mannose trimming	Any protein alpha-1,2-demannosylation that takes place in the endoplasmic reticulum quality control compartment (ERQC).	tmpzr1t_l9r_go_relaxed.owl	protein alpha-1,2-demannosylation in endoplasmic reticulum|ER protein alpha-1,2-demannosylation|glycoprotein mannose trimming in ER quality control compartment|glycoprotein mannose trimming in endoplasmic reticulum quality control compartment|protein alpha-1,2-demannosylation in ERQC|protein alpha-1,2-demannosylation in ER quality control compartment|glycoprotein mannose trimming in ER-derived quality control compartment|protein alpha-1,2-demannosylation in endoplasmic reticulum quality control compartment|protein alpha-1,2-demannosylation in ER|protein alpha-1,2-demannosylation in ER-derived quality control compartment|ER mannose trimming|glycoprotein mannose trimming in ERQC							bf	2015-06-23T09:35:41Z					biological_process											owl:Class	
GO:0070250	biolink:NamedThing	mating projection membrane	The portion of the plasma membrane surrounding a mating projection, the projection formed by unicellular fungi in response to mating pheromone.	tmpzr1t_l9r_go_relaxed.owl	shmoo membrane													cellular_component											owl:Class	
GO:0006089	biolink:NamedThing	lactate metabolic process	The chemical reactions and pathways involving lactate, the anion of lactic acid.	tmpzr1t_l9r_go_relaxed.owl	2-hydroxypropanoate metabolic process|alpha-hydroxypropionate metabolism|alpha-hydroxypropionate metabolic process|lactate metabolism|2-hydroxypropanoate metabolism													biological_process											owl:Class	
GO:1901923	biolink:NamedThing	negative regulation of sclerotium development	Any process that stops, prevents or reduces the frequency, rate or extent of sclerotium development.	tmpzr1t_l9r_go_relaxed.owl	down regulation of sclerotium development|inhibition of sclerotium development|downregulation of sclerotium development|down-regulation of sclerotium development							di	2013-02-15T20:00:23Z					biological_process											owl:Class	
GO:0030729	biolink:NamedThing	acetoacetate-CoA ligase activity	Catalysis of the reaction: acetoacetate + ATP + CoA = acetoacetyl-CoA + AMP + diphosphate + H(+).	tmpzr1t_l9r_go_relaxed.owl	acetoacetyl-CoA synthetase activity|acetoacetate:CoA ligase (AMP-forming)				EC:6.2.1.16|MetaCyc:ACETOACETATE--COA-LIGASE-RXN|Reactome:R-HSA-5694494|RHEA:16117|KEGG_REACTION:R01357									molecular_function											owl:Class	
GO:0061926	biolink:NamedThing	positive regulation of formation of radial glial scaffolds	Any process that increases the frequency, rate or extent of the formation of radial glial cell scaffolds.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of Bergmann fiber biosynthesis|positive regulation of radial glial scaffold formation|positive regulation of Bergmann fiber formation							dph	2017-08-02T16:29:37Z					biological_process											owl:Class	
GO:1902797	biolink:NamedThing	negative regulation of snoRNA processing	Any process that stops, prevents or reduces the frequency, rate or extent of snoRNA processing.	tmpzr1t_l9r_go_relaxed.owl	downregulation of snoRNA processing|down-regulation of snoRNA processing|down regulation of snoRNA processing|inhibition of snoRNA processing							mah	2014-03-24T12:47:08Z					biological_process											owl:Class	
GO:1903667	biolink:NamedThing	regulation of chemorepellent activity	Any process that modulates the frequency, rate or extent of chemorepellent activity.	tmpzr1t_l9r_go_relaxed.owl	regulation of chemorepellant activity							pf	2014-11-26T23:58:33Z					biological_process											owl:Class	
GO:0030317	biolink:NamedThing	flagellated sperm motility	The directed, self-propelled movement of a cilium (aka flagellum) that contributes to the movement of a flagellated sperm.	tmpzr1t_l9r_go_relaxed.owl	sperm flagellum movement involved in flagellated sperm motility|sperm motility|sperm flagellum movement|sperm movement|flagellated sperm movement|sperm flagellum movement involved in flagellated sperm movement				Wikipedia:Sperm_motility							GO:1905419|GO:0097724		biological_process											owl:Class	
GO:0060294	biolink:NamedThing	cilium movement involved in cell motility	Movement of cilia mediated by motor proteins that contributes to the movement of a cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0002862	biolink:NamedThing	negative regulation of inflammatory response to antigenic stimulus	Any process that stops, prevents, or reduces the frequency, rate, or extent of an inflammatory response to an antigenic stimulus.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of inflammatory response to antigenic stimulus|down regulation of inflammatory response to antigenic stimulus|inhibition of inflammatory response to antigenic stimulus|downregulation of inflammatory response to antigenic stimulus													biological_process											owl:Class	
GO:0014910	biolink:NamedThing	regulation of smooth muscle cell migration	Any process that modulates the frequency, rate or extent of smooth muscle cell migration.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1904544	biolink:NamedThing	positive regulation of free ubiquitin chain polymerization	Any process that activates or increases the frequency, rate or extent of free ubiquitin chain polymerization.	tmpzr1t_l9r_go_relaxed.owl	upregulation of free ubiquitin chain polymerization|up regulation of free ubiquitin chain polymerization|up-regulation of free ubiquitin chain polymerization|activation of free ubiquitin chain polymerization					An example of this is PARK2 in human (UniProt symbol O60260) in PMID:24660806 (inferred from mutant phenotype).		pad	2015-08-11T11:45:06Z					biological_process											owl:Class	
GO:0002260	biolink:NamedThing	lymphocyte homeostasis	The process of regulating the proliferation and elimination of lymphocytes such that the total number of lymphocytes within a whole or part of an organism is stable over time in the absence of an outside stimulus.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0001776	biolink:NamedThing	leukocyte homeostasis	The process of regulating the proliferation and elimination of cells of the immune system such that the total number of cells of a particular cell type within a whole or part of an organism is stable over time in the absence of an outside stimulus.	tmpzr1t_l9r_go_relaxed.owl	immune cell homeostasis|leucocyte homeostasis					Note that this term represents the return of immune system cell levels to stable numbers following an immune response as well as the proliferation and elimination of cells of the immune system required to maintain stable numbers in the absence of an outside stimulus.								biological_process											owl:Class	
GO:0015943	biolink:NamedThing	formate biosynthetic process	The chemical reactions and pathways resulting in the formation of formate, also known as methanoate, the anion HCOO- derived from methanoic (formic) acid.	tmpzr1t_l9r_go_relaxed.owl	formic acid biosynthesis|formic acid biosynthetic process|formate formation|formate biosynthesis|formate anabolism|formate synthesis													biological_process											owl:Class	
GO:0090502	biolink:NamedThing	RNA phosphodiester bond hydrolysis, endonucleolytic	The chemical reactions and pathways involving the hydrolysis of internal 3',5'-phosphodiester bonds in one or two strands of ribonucleotides.	tmpzr1t_l9r_go_relaxed.owl								tb	2012-10-22T12:05:27Z					biological_process											owl:Class	
GO:0090501	biolink:NamedThing	RNA phosphodiester bond hydrolysis	The RNA metabolic process in which the phosphodiester bonds between ribonucleotides are cleaved by hydrolysis.	tmpzr1t_l9r_go_relaxed.owl								tb	2012-10-22T12:05:27Z					biological_process											owl:Class	
GO:0006820	biolink:NamedThing	anion transport	The directed movement of anions, atoms or small molecules with a net negative charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl												GO:0006822		biological_process											owl:Class	
GO:0035985	biolink:NamedThing	senescence-associated heterochromatin focus	A transcriptionally-silent heterochromatin structure present in senescent cells. Contains the condensed chromatin of one chromosome and is enriched for histone modifications. Thought to repress expression of proliferation-promoting genes.	tmpzr1t_l9r_go_relaxed.owl	SAHF|senescence-associated heterochromatin foci							bf	2011-08-25T04:36:40Z					cellular_component											owl:Class	
GO:0000792	biolink:NamedThing	heterochromatin	A compact and highly condensed form of chromatin.	tmpzr1t_l9r_go_relaxed.owl	nuclear heterochromatin				Wikipedia:Heterochromatin|NIF_Subcellular:sao581845896							GO:0005720		cellular_component											owl:Class	
GO:0045754	biolink:NamedThing	positive regulation of acetate catabolic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of acetate.	tmpzr1t_l9r_go_relaxed.owl	stimulation of acetate catabolic process|up regulation of acetate catabolic process|upregulation of acetate catabolic process|positive regulation of acetate catabolism|positive regulation of acetate degradation|up-regulation of acetate catabolic process|positive regulation of acetate breakdown|activation of acetate catabolic process													biological_process											owl:Class	
GO:0048198	biolink:NamedThing	Golgi vesicle bud deformation and release	The process in which cytosolic coat proteins fit together in a basketlike convex framework to form a coated deformed region on the cytoplasmic surface of the membrane. The deformed region forms into a complete vesicle and is released.	tmpzr1t_l9r_go_relaxed.owl	Golgi-derived vesicle bud deformation and release|dictyosome vesicle bud deformation													biological_process											owl:Class	
GO:0140345	biolink:NamedThing	phosphatidylcholine flippase activity	Catalysis of the movement of phosphatidylcholine from the exoplasmic to the cytosolic leaftlet of a membrane, using energy from the hydrolysis of ATP.	tmpzr1t_l9r_go_relaxed.owl	phosphatidylcholine flippase activity (exoplasmic to cytosolic leaftlet)							pg	2019-05-16T13:43:47Z					molecular_function											owl:Class	
GO:0140333	biolink:NamedThing	glycerophospholipid flippase activity	Catalysis of the movement of a glycerophospholipid from the exoplasmic to the cytosolic leaftlet of a membrane, using energy from the hydrolysis of ATP.	tmpzr1t_l9r_go_relaxed.owl	glycerophospholipid flippase activity (exoplasmic to cytosolic leaftlet)							pg	2019-05-13T11:14:56Z					molecular_function											owl:Class	
GO:0060351	biolink:NamedThing	cartilage development involved in endochondral bone morphogenesis	The process whose specific outcome is the progression of the cartilage that will provide a scaffold for mineralization of endochondral bones.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0051216	biolink:NamedThing	cartilage development	The process whose specific outcome is the progression of a cartilage element over time, from its formation to the mature structure. Cartilage elements are skeletal elements that consist of connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate.	tmpzr1t_l9r_go_relaxed.owl	cartilage element development|chondrogenesis|cartilage biogenesis|cartilage formation|cartilage biosynthesis|cartilage organ development				Wikipedia:Chondrogenesis									biological_process											owl:Class	
GO:0033031	biolink:NamedThing	positive regulation of neutrophil apoptotic process	Any process that activates or increases the frequency, rate, or extent of neutrophil apoptotic process.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of neutrophil apoptosis|stimulation of neutrophil apoptosis|up-regulation of neutrophil apoptosis|upregulation of neutrophil apoptosis|activation of neutrophil apoptosis|up regulation of neutrophil apoptosis													biological_process											owl:Class	
GO:0033029	biolink:NamedThing	regulation of neutrophil apoptotic process	Any process that modulates the frequency, rate, or extent of neutrophil apoptotic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of neutrophil apoptosis													biological_process											owl:Class	
GO:1901477	biolink:NamedThing	benomyl transmembrane transport	The directed movement of benomyl across a membrane.	tmpzr1t_l9r_go_relaxed.owl	benomyl membrane transport					Note that this term is not intended for use in annotating lateral movement within membranes.		tb	2012-10-04T23:11:36Z					biological_process											owl:Class	
GO:1902329	biolink:NamedThing	bacterial-type DNA replication termination	Any DNA replication termination that is involved in bacterial-type DNA replication.	tmpzr1t_l9r_go_relaxed.owl	DNA replication termination involved in bacterial-type DNA replication							jl	2013-07-25T10:48:10Z					biological_process											owl:Class	
GO:1902294	biolink:NamedThing	cell cycle DNA replication termination	Any DNA replication termination that is involved in cell cycle DNA replication.	tmpzr1t_l9r_go_relaxed.owl	DNA replication termination involved in cell cycle DNA replication							jl	2013-07-09T16:06:11Z					biological_process											owl:Class	
GO:0010060	biolink:NamedThing	negative regulation of atrichoblast fate specification	Any process that suppresses atrichoblast fate specification.	tmpzr1t_l9r_go_relaxed.owl	downregulation of atrichoblast fate|down regulation of atrichoblast fate|down-regulation of atrichoblast fate|inhibition of atrichoblast fate													biological_process											owl:Class	
GO:0032293	biolink:NamedThing	non-myelinated axon ensheathment in central nervous system	The process in which a non-myelinating glial cell membrane encircles an axon in the central nervous system.	tmpzr1t_l9r_go_relaxed.owl	ensheathment of non-myelinated axons in central nervous system													biological_process											owl:Class	
GO:0032291	biolink:NamedThing	axon ensheathment in central nervous system	The process in which a glial cell membrane closes around an axon in the central nervous system. This can be a myelinating or a non-myelinating neuron-glial interaction.	tmpzr1t_l9r_go_relaxed.owl	ensheathment of axons in central nervous system													biological_process											owl:Class	
GO:1903785	biolink:NamedThing	L-valine transmembrane transport	The directed movement of L-valine across a membrane.	tmpzr1t_l9r_go_relaxed.owl								al	2015-01-08T14:50:32Z					biological_process											owl:Class	
GO:0005009	biolink:NamedThing	insulin-activated receptor activity	Combining with insulin and transmitting the signal across the plasma membrane to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	insulin receptor activity					Note that this term represents an activity and not a gene product, and should only be used when the receptor binds the ligand insulin. For receptors that bind other extracellular ligands, consider annotating to other terms under 'transmembrane signaling receptor activity ; GO:0004888.								molecular_function											owl:Class	
GO:0004714	biolink:NamedThing	transmembrane receptor protein tyrosine kinase activity	Combining with a signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: ATP + a protein-L-tyrosine = ADP + a protein-L-tyrosine phosphate.	tmpzr1t_l9r_go_relaxed.owl	receptor protein-tyrosine kinase activity|receptor protein tyrosine kinase activity				Reactome:R-HSA-198295|Reactome:R-HSA-167683|Reactome:R-HSA-8950757|Reactome:R-HSA-8950269|Reactome:R-HSA-8987084|Reactome:R-HSA-8987096|Reactome:R-HSA-166544|Reactome:R-HSA-8986995|Reactome:R-HSA-8987202|Reactome:R-HSA-74742|Reactome:R-HSA-8852552|Reactome:R-HSA-8950340|Reactome:R-HSA-8983300|Reactome:R-HSA-8950453|Reactome:R-HSA-6784324|Reactome:R-HSA-8987012|Reactome:R-HSA-8950354|Reactome:R-HSA-8986994|Reactome:R-HSA-8987042|Reactome:R-HSA-8987141|Reactome:R-HSA-8987040|Reactome:R-HSA-8987070|EC:2.7.10.1|Reactome:R-HSA-8987150|Reactome:R-HSA-167019|Reactome:R-HSA-8950485|Reactome:R-HSA-8950537|Reactome:R-HSA-177933|Reactome:R-HSA-8983371|Reactome:R-HSA-8983309|Reactome:R-HSA-8950591|Reactome:R-HSA-8950405|Reactome:R-HSA-8987129|Reactome:R-HSA-8987255|Reactome:R-HSA-74715|Reactome:R-HSA-8950364|Reactome:R-HSA-8982163|MetaCyc:2.7.10.1-RXN|Reactome:R-HSA-8987179|Reactome:R-HSA-8853792|Reactome:R-HSA-8986985|Reactome:R-HSA-74711|Reactome:R-HSA-8950423|Reactome:R-HSA-169905|Reactome:R-HSA-8983424									molecular_function											owl:Class	
GO:0032414	biolink:NamedThing	positive regulation of ion transmembrane transporter activity	Any process that activates or increases the activity of an ion transporter.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of ion transporter activity|upregulation of ion transporter activity|positive regulation of ion transporter activity|activation of ion transporter activity|stimulation of ion transporter activity|up regulation of ion transporter activity													biological_process											owl:Class	
GO:0046078	biolink:NamedThing	dUMP metabolic process	The chemical reactions and pathways involving dUMP, deoxyuridine (5'-)monophosphate (2'-deoxyuridine 5'-phosphate).	tmpzr1t_l9r_go_relaxed.owl	dUMP metabolism													biological_process											owl:Class	
GO:0042360	biolink:NamedThing	vitamin E metabolic process	The chemical reactions and pathways involving vitamin E, tocopherol, which includes a series of eight structurally similar compounds. Alpha-tocopherol is the most active form in humans and is a powerful biological antioxidant.	tmpzr1t_l9r_go_relaxed.owl	alpha-tocopherol metabolism|tocopherol metabolic process|vitamin E metabolism|alpha-tocopherol metabolic process|tocopherol metabolism													biological_process											owl:Class	
GO:0044545	biolink:NamedThing	NSL complex	A histone acetyltransferase complex that catalyzes the acetylation of a histone H4 lysine residues at several positions. In human, it contains the catalytic subunit MOF, NSL1/KIAA1267, NSL2/KANSL2, NSL3/KANSL3, MCRS1, PHF20, OGT1, WDR5 and HCF1.	tmpzr1t_l9r_go_relaxed.owl	non-specific lethal complex							jl	2012-03-22T12:49:18Z					cellular_component											owl:Class	
GO:1902562	biolink:NamedThing	H4 histone acetyltransferase complex	A protein complex which is capable of H4 histone acetyltransferase activity.	tmpzr1t_l9r_go_relaxed.owl	Hpa3 complex|Hpa3 (homo-)dimer					An example of this is Hpa2 in yeast [Q06592] in PMID:23775086 [IDA].		bhm	2013-12-10T14:43:51Z					cellular_component											owl:Class	
GO:0004662	biolink:NamedThing	CAAX-protein geranylgeranyltransferase activity	Catalysis of the reaction: geranylgeranyl diphosphate + protein-cysteine = S-geranylgeranyl-protein + diphosphate. This reaction is the formation of a thioether linkage between the C-1 atom of the geranylgeranyl group and a cysteine residue fourth from the C-terminus of the protein. The protein substrates have the C-terminal sequence CA1A2X, where the terminal residue, X, is preferably leucine and A2 should not be aromatic. Known substrates include most g-subunits of heterotrimeric G proteins and Ras-related GTPases such as members of the Ras and Rac/Rho families.	tmpzr1t_l9r_go_relaxed.owl	GGTase-I activity|geranylgeranyl-diphosphate:protein-cysteine geranyltransferase activity|type I protein geranyl-geranyltransferase activity|GGTaseI activity|geranylgeranyltransferase type I activity|protein geranylgeranyltransferase type I				MetaCyc:RXN-3701|EC:2.5.1.59|MetaCyc:2.5.1.60-RXN									molecular_function											owl:Class	
GO:0004661	biolink:NamedThing	protein geranylgeranyltransferase activity	Catalysis of the covalent addition of a geranylgeranyl (20-carbon isoprenoid) group via thioether linkages to a cysteine residue at or near the C terminus of a protein.	tmpzr1t_l9r_go_relaxed.owl	protein-cysteine geranylgeranyltransferase activity											GO:0018224		molecular_function											owl:Class	
GO:0090301	biolink:NamedThing	negative regulation of neural crest formation	Any process that decreases the rate, frequency, or extent of neural crest formation. Neural crest formation is the formation of the specialized region of ectoderm between the neural ectoderm (neural plate) and non-neural ectoderm. The neural crest gives rise to the neural crest cells that migrate away from this region as neural tube formation procedes.	tmpzr1t_l9r_go_relaxed.owl								tb	2010-03-12T04:08:26Z					biological_process											owl:Class	
GO:0031338	biolink:NamedThing	regulation of vesicle fusion	Any process that modulates the frequency, rate or extent of vesicle fusion.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0043555	biolink:NamedThing	regulation of translation in response to stress	Modulation of the frequency, rate or extent of translation as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).	tmpzr1t_l9r_go_relaxed.owl	translational stress response													biological_process											owl:Class	
GO:0015111	biolink:NamedThing	iodide transmembrane transporter activity	Enables the transfer of iodide ions from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-5627802|Reactome:R-HSA-5627870|Reactome:R-HSA-209910									molecular_function											owl:Class	
GO:0035820	biolink:NamedThing	negative regulation of renal sodium excretion by angiotensin	The process in which angiotensin decreases the amount of sodium that is excreted in urine over a unit of time.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-04-20T02:10:50Z					biological_process											owl:Class	
GO:0003083	biolink:NamedThing	negative regulation of renal output by angiotensin	The process in which angiotensin directly decreases the rate of natriuresis and diuresis in the kidney.	tmpzr1t_l9r_go_relaxed.owl	angiotensin mediated negative regulation of renal output|angiotensin-mediated negative regulation of renal output													biological_process											owl:Class	
GO:0060884	biolink:NamedThing	clearance of cells from fusion plate	The morphogenetic process in which cells are removed from the inner loop of a semicircular canal.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-08-13T12:25:59Z					biological_process											owl:Class	
GO:0034369	biolink:NamedThing	plasma lipoprotein particle remodeling	The acquisition, loss or modification of a protein or lipid within a plasma lipoprotein particle, including the hydrolysis of triglyceride by hepatic lipase, with the subsequent loss of free fatty acid, and the esterification of cholesterol by phosphatidylcholine-sterol O-acyltransferase (lecithin cholesterol acyltransferase; LCAT).	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0034368	biolink:NamedThing	protein-lipid complex remodeling	The acquisition, loss or modification of a protein or lipid within a protein-lipid complex.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0097485	biolink:NamedThing	neuron projection guidance	The process in which the migration of a neuron projection is directed to a specific target site in response to a combination of attractive and repulsive cues.	tmpzr1t_l9r_go_relaxed.owl	neuron process guidance|neuronal cell projection guidance|neurite guidance|neuron protrusion guidance							pr	2013-07-08T13:32:37Z					biological_process											owl:Class	
GO:0006928	biolink:NamedThing	movement of cell or subcellular component	The directed, self-propelled movement of a cell or subcellular component without the involvement of an external agent such as a transporter or a pore.	tmpzr1t_l9r_go_relaxed.owl	cellular component motion|cell movement|cellular component movement					Note that in GO cellular components include whole cells (cell is_a cellular component).								biological_process											owl:Class	
GO:0071232	biolink:NamedThing	cellular response to histidine	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a histidine stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-12-03T02:09:15Z					biological_process											owl:Class	
GO:0071230	biolink:NamedThing	cellular response to amino acid stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amino acid stimulus. An amino acid is a carboxylic acids containing one or more amino groups.	tmpzr1t_l9r_go_relaxed.owl	cellular response to amino acid							mah	2009-12-03T02:08:11Z					biological_process											owl:Class	
GO:2001286	biolink:NamedThing	regulation of caveolin-mediated endocytosis	Any process that modulates the frequency, rate or extent of caveolin-mediated endocytosis.	tmpzr1t_l9r_go_relaxed.owl	regulation of caveolin-dependent endocytosis|regulation of caveolae-dependent endocytosis|regulation of caveolae-mediated endocytosis							yaf	2011-12-15T04:13:19Z					biological_process											owl:Class	
GO:0102707	biolink:NamedThing	S-adenosyl-L-methionine:beta-alanine N-methyltransferase activity	Catalysis of the reaction: beta-alanine + S-adenosyl-L-methionine  = H+ + N-methyl-beta-alanine + S-adenosyl-L-homocysteine.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-6461|EC:2.1.1.49									molecular_function											owl:Class	
GO:0140652	biolink:NamedThing	pyripyropene A biosynthetic process	The chemical reactions and pathways resulting in the formation of pyripyropene A.	tmpzr1t_l9r_go_relaxed.owl	pyripyropene A formation|pyripyropene A synthesis|pyripyropene A biosynthesis|pyripyropene A anabolism	https://github.com/geneontology/go-ontology/issues/21496						pg	2021-05-27T08:33:29Z					biological_process											owl:Class	
GO:0051103	biolink:NamedThing	DNA ligation involved in DNA repair	The re-formation of a broken phosphodiester bond in the DNA backbone, carried out by DNA ligase, that contributes to DNA repair.	tmpzr1t_l9r_go_relaxed.owl	DNA ligation during DNA repair													biological_process											owl:Class	
GO:0008348	biolink:NamedThing	negative regulation of antimicrobial humoral response	Any process that stops, prevents, or reduces the frequency, rate, or extent of an antimicrobial humoral response.	tmpzr1t_l9r_go_relaxed.owl	inhibition of antimicrobial humoral response|attenuation of antimicrobial humoral response|down regulation of antimicrobial humoral response|downregulation of antimicrobial humoral response|down-regulation of antimicrobial humoral response											GO:0042154|GO:0042155		biological_process											owl:Class	
GO:0072199	biolink:NamedThing	regulation of mesenchymal cell proliferation involved in ureter development	Any process that modulates the frequency, rate or extent of mesenchymal cell proliferation that contributes to the progression of the ureter gland over time. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets.	tmpzr1t_l9r_go_relaxed.owl	regulation of ureteral mesenchymal cell proliferation|regulation of ureter mesenchymal cell proliferation							mah	2010-03-01T03:38:13Z					biological_process											owl:Class	
GO:1990724	biolink:NamedThing	galectin complex	A homodimeric protein complex that is capable of binding a range of carbohydrates and is involved in anti-inflammatory and pro-apoptotic processes.	tmpzr1t_l9r_go_relaxed.owl	galectin-2 complex|galectin-1 complex					An example of this is Galectin-1 in human (P09382) in PMID:15476813 (inferred from physical interaction).		bhm	2015-04-07T15:03:15Z					cellular_component											owl:Class	
GO:0098635	biolink:NamedThing	protein complex involved in cell-cell adhesion	Any protein complex that is capable of carrying out some part of the process of cell-cell adhesion.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0042989	biolink:NamedThing	sequestering of actin monomers	The selective interaction of actin monomers with specific molecules that inhibit their polymerization by preventing their access to other monomers.	tmpzr1t_l9r_go_relaxed.owl	actin monomer sequestering activity|storage of actin monomers|retention of actin monomers|actin monomer retention|actin monomer sequestering|actin monomer storage|actin monomer sequestration|sequestration of actin monomers													biological_process											owl:Class	
GO:0062128	biolink:NamedThing	MutSgamma complex	A heterodimer involved in the stabilization of DNA recombination intermediates, the promotion of crossover recombination, and the proper assembly of the synaptonemal complex in meiotic prophase nuclei. In yeast the complex consists of two subunits, Msh4 and Msh5.	tmpzr1t_l9r_go_relaxed.owl	Msh4-Msh5 complex							dph	2019-06-04T14:48:15Z					cellular_component											owl:Class	
GO:0103081	biolink:NamedThing	methylthiopropylmalate dehydrogenase activity	Catalysis of the reaction: 3-(3'-methylthio)propylmalate <=> H+ + 2-oxo-6-methylthiohexanoate + carbon dioxide.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXNQT-4165									molecular_function											owl:Class	
GO:0019588	biolink:NamedThing	anaerobic glycerol catabolic process	The anaerobic chemical reactions and pathways resulting in the breakdown of glycerol, yielding energy in the form of ATP.	tmpzr1t_l9r_go_relaxed.owl	glycerol fermentation													biological_process											owl:Class	
GO:0019563	biolink:NamedThing	glycerol catabolic process	The chemical reactions and pathways resulting in the breakdown of glycerol, 1,2,3-propanetriol, a sweet, hygroscopic, viscous liquid, widely distributed in nature as a constituent of many lipids.	tmpzr1t_l9r_go_relaxed.owl	glycerol breakdown|glycerol degradation|glycerol catabolism				MetaCyc:PWY0-381|MetaCyc:PWY-4261									biological_process											owl:Class	
GO:0102229	biolink:NamedThing	amylopectin maltohydrolase activity	Catalysis of the reaction: n H2O + an exposed unphosphorylated, unbranched malto-oligosaccharide tail on amylopectin <=> amylopectin + maltose.	tmpzr1t_l9r_go_relaxed.owl					EC:3.2.1.2|MetaCyc:RXN-12278									molecular_function											owl:Class	
GO:0043455	biolink:NamedThing	regulation of secondary metabolic process	Any process that modulates the frequency, rate or extent of secondary metabolism, the chemical reactions and pathways involving compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon.	tmpzr1t_l9r_go_relaxed.owl	regulation of secondary metabolism													biological_process											owl:Class	
GO:1902835	biolink:NamedThing	negative regulation of proline import across plasma membrane	Any process that stops, prevents or reduces the frequency, rate or extent of proline import into cell.	tmpzr1t_l9r_go_relaxed.owl	inhibition of proline import into cell|down regulation of proline import into cell|down-regulation of proline import into cell|downregulation of proline import into cell|negative regulation of proline import into cell							mah	2014-04-01T13:44:06Z					biological_process											owl:Class	
GO:1902834	biolink:NamedThing	regulation of proline import across plasma membrane	Any process that modulates the frequency, rate or extent of proline import into cell.	tmpzr1t_l9r_go_relaxed.owl	regulation of proline import into cell							mah	2014-04-01T13:44:00Z					biological_process											owl:Class	
GO:0006248	biolink:NamedThing	CMP catabolic process	The chemical reactions and pathways resulting in the breakdown of CMP, cytidine monophosphate.	tmpzr1t_l9r_go_relaxed.owl	CMP catabolism|CMP breakdown|CMP degradation													biological_process											owl:Class	
GO:0009175	biolink:NamedThing	pyrimidine ribonucleoside monophosphate catabolic process	The chemical reactions and pathways resulting in the breakdown of pyrimidine ribonucleoside monophosphate, a compound consisting of a pyrimidine base linked to a ribose sugar esterified with phosphate on the sugar.	tmpzr1t_l9r_go_relaxed.owl	pyrimidine ribonucleoside monophosphate degradation|pyrimidine ribonucleoside monophosphate breakdown|pyrimidine ribonucleoside monophosphate catabolism													biological_process											owl:Class	
GO:0043463	biolink:NamedThing	regulation of rhamnose catabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of rhamnose, the hexose 6-deoxy-L-mannose.	tmpzr1t_l9r_go_relaxed.owl	regulation of rhamnose breakdown|regulation of rhamnose degradation|regulation of rhamnose catabolism													biological_process											owl:Class	
GO:0046541	biolink:NamedThing	saliva secretion	The regulated release of saliva from the salivary glands. In man, the saliva is a turbid and slightly viscous fluid, generally of an alkaline reaction, and is secreted by the parotid, submaxillary, and sublingual glands. In the mouth the saliva is mixed with the secretion from the buccal glands. In man and many animals, saliva is an important digestive fluid on account of the presence of the peculiar enzyme, ptyalin.	tmpzr1t_l9r_go_relaxed.owl	salivation				Wikipedia:Salivation									biological_process											owl:Class	
GO:1905626	biolink:NamedThing	positive regulation of L-methionine import across plasma membrane	Any process that activates or increases the frequency, rate or extent of L-methionine import across plasma membrane.	tmpzr1t_l9r_go_relaxed.owl								vw	2016-10-29T16:27:46Z					biological_process											owl:Class	
GO:0004707	biolink:NamedThing	MAP kinase activity	Catalysis of the reaction: protein + ATP = protein phosphate + ADP. This reaction is the phosphorylation of proteins. Mitogen-activated protein kinase; a family of protein kinases that perform a crucial step in relaying signals from the plasma membrane to the nucleus. They are activated by a wide range of proliferation- or differentiation-inducing signals; activation is strong with agonists such as polypeptide growth factors and tumor-promoting phorbol esters, but weak (in most cell backgrounds) by stress stimuli.	tmpzr1t_l9r_go_relaxed.owl	ERK|MBP kinase I activity|mitogen activated kinase activity|mitogen-activated protein kinase activity|MAP kinase 1 activity|SAPK|ERK2|MBP kinase II activity|MAPK|stress-activated kinase activity|ERK1|stress-activated protein kinase activity|extracellular signal-regulated kinase activity|myelin basic protein kinase activity|SAP kinase activity|MAP kinase 2 activity|ATP:protein phosphotransferase (MAPKK-activated) activity				EC:2.7.11.24|Reactome:R-HSA-198733|Reactome:R-HSA-451366|Reactome:R-HSA-5654566|Reactome:R-HSA-5654565|Reactome:R-HSA-111898|Reactome:R-HSA-5654560|MetaCyc:2.7.11.24-RXN|Reactome:R-HSA-445079|KEGG_REACTION:R00162|Reactome:R-HSA-5654562|Reactome:R-HSA-73722|Reactome:R-HSA-9626832							GO:0008338|GO:0008339|GO:0016908|GO:0016909		molecular_function											owl:Class	
GO:0004303	biolink:NamedThing	estradiol 17-beta-dehydrogenase activity	Catalysis of the reaction: estradiol-17-beta + NADP+ = estrone + NADPH + H+.	tmpzr1t_l9r_go_relaxed.owl	17beta-hydroxysteroid dehydrogenase activity|20alpha-hydroxysteroid dehydrogenase|estradiol-17beta:NAD(P)+ 17-oxidoreductase activity|17beta,20alpha-hydroxysteroid dehydrogenase activity|17beta-HSD|estrogen 17-oxidoreductase activity|estradiol dehydrogenase activity|17-beta-estradiol dehydrogenase activity|estradiol 17beta-dehydrogenase activity|17-beta-hydroxysteroid dehydrogenase activity|17-beta-HSD activity|17beta-estradiol dehydrogenase activity				EC:1.1.1.62|Reactome:R-HSA-5696822|Reactome:R-HSA-5693390|Reactome:R-HSA-6810594|Reactome:R-HSA-804969|MetaCyc:ESTRADIOL-17-BETA-DEHYDROGENASE-RXN|Reactome:R-HSA-8862137									molecular_function											owl:Class	
GO:2000485	biolink:NamedThing	regulation of glutamine transport	Any process that modulates the frequency, rate or extent of glutamine transport.	tmpzr1t_l9r_go_relaxed.owl	regulation of L-glutamine transport							bf	2011-03-11T09:32:23Z					biological_process											owl:Class	
GO:0060873	biolink:NamedThing	anterior semicircular canal development	The progession of the anterior semicircular canal from its initial formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-08-13T09:39:49Z					biological_process											owl:Class	
GO:0019360	biolink:NamedThing	nicotinamide nucleotide biosynthetic process from niacinamide	The chemical reactions and pathways resulting in the formation of nicotinamide nucleotide from other compounds, including niacinamide.	tmpzr1t_l9r_go_relaxed.owl	nicotinamide nucleotide synthesis from niacinamide|nicotinamide nucleotide formation from niacinamide|nicotinamide nucleotide anabolism from niacinamide													biological_process											owl:Class	
GO:0042200	biolink:NamedThing	cyanuric acid catabolic process	The chemical reactions and pathways resulting in the breakdown of cyanuric acid, a potential degradation product of triazine herbicides.	tmpzr1t_l9r_go_relaxed.owl	cyanuric acid breakdown|cyanuric acid catabolism|cyanuric acid degradation				UM-BBD_pathwayID:cya									biological_process											owl:Class	
GO:0042199	biolink:NamedThing	cyanuric acid metabolic process	The chemical reactions and pathways involving cyanuric acid, a suspected gastrointestinal or liver toxicant, and a potential degradation product of triazine herbicides, such as atrazine and simazine. It is widely used for the stabilization of available chlorine in swimming pool water and is also the starting compound for the synthesis of many organic derivatives.	tmpzr1t_l9r_go_relaxed.owl	cyanuric acid metabolism													biological_process											owl:Class	
GO:0051554	biolink:NamedThing	flavonol metabolic process	The chemical reactions and pathways involving flavonols, a member of a class of vascular pigments formed by consecutive oxidative processes from the flavonoid intermediates flavanones and dihydroflavonols. Flavonols are the most widespread of the flavonoids and have a wide array of physiological activities.	tmpzr1t_l9r_go_relaxed.owl	flavonol metabolism													biological_process											owl:Class	
GO:0102721	biolink:NamedThing	ubiquinol:oxygen oxidoreductase activity	Catalysis of the reaction: O2 + 2 an ubiquinol = 2 H2O + 2 an ubiquinone.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-6883|EC:1.10.3.11|RHEA:30255									molecular_function											owl:Class	
GO:0032361	biolink:NamedThing	pyridoxal phosphate catabolic process	The chemical reactions and pathways resulting in the breakdown of pyridoxal phosphate, pyridoxal phosphorylated at the hydroxymethyl group of C-5, the active form of vitamin B6.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0042822	biolink:NamedThing	pyridoxal phosphate metabolic process	The chemical reactions and pathways involving pyridoxal phosphate, pyridoxal phosphorylated at the hydroxymethyl group of C-5, the active form of vitamin B6.	tmpzr1t_l9r_go_relaxed.owl	active vitamin B6 metabolism|active vitamin B6 metabolic process|pyridoxal phosphate metabolism													biological_process											owl:Class	
GO:0052710	biolink:NamedThing	N-alpha,N-alpha,N-alpha-trimethyl-L-histidine catabolic process	The chemical reactions and pathways resulting in the breakdown of N-alpha,N-alpha,N-alpha-trimethyl-L-histidine, also known as histidine betaine or hercynine, a trimethylated derivative of histidine.	tmpzr1t_l9r_go_relaxed.owl	hercynine breakdown|histidine betaine breakdown|hercynine catabolism|N-alpha,N-alpha,N-alpha-trimethyl-L-histidine breakdown|N-alpha,N-alpha,N-alpha-trimethyl-L-histidine catabolism|histidine betaine degradation|N-alpha,N-alpha,N-alpha-trimethyl-L-histidine degradation|histidine betaine catabolic process|histidine betaine catabolism|hercynine catabolic process|hercynine degradation							ai	2011-08-05T02:22:54Z					biological_process											owl:Class	
GO:0052708	biolink:NamedThing	N-alpha,N-alpha,N-alpha-trimethyl-L-histidine metabolic process	The chemical reactions and pathways involving N-alpha,N-alpha,N-alpha-trimethyl-L-histidine, also known as histidine betaine or hercynine, a trimethylated derivative of histidine.	tmpzr1t_l9r_go_relaxed.owl	histidine betaine metabolism|N-alpha,N-alpha,N-alpha-trimethyl-L-histidine metabolism|histidine betaine metabolic process|hercynine metabolism|hercynine metabolic process							ai	2011-08-05T02:13:31Z					biological_process											owl:Class	
GO:0150136	biolink:NamedThing	regulation of interleukin-37 production	Any process that modulates the frequency, rate or extent of interleukin-37 production.	tmpzr1t_l9r_go_relaxed.owl	regulation of interleukin-37 biosynthetic process							bc	2019-12-08T08:39:07Z					biological_process											owl:Class	
GO:1903257	biolink:NamedThing	selenoneine biosynthetic process	The chemical reactions and pathways resulting in the formation of selenoneine.	tmpzr1t_l9r_go_relaxed.owl	selenoneine anabolism|selenoneine synthesis|selenoneine formation|selenoneine biosynthesis|L-selenoneine biosynthetic process							mah	2014-08-06T09:14:33Z					biological_process											owl:Class	
GO:0006578	biolink:NamedThing	amino-acid betaine biosynthetic process	The chemical reactions and pathways resulting in the formation of any betaine, the N-trimethyl derivative of an amino acid.	tmpzr1t_l9r_go_relaxed.owl	betaine formation|betaine biosynthesis|betaine anabolism|betaine synthesis|betaine biosynthetic process													biological_process											owl:Class	
GO:0045837	biolink:NamedThing	negative regulation of membrane potential	Any process that stops, prevents, or reduces the frequency, rate or extent of establishment or extent of a membrane potential, the electric potential existing across any membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane.	tmpzr1t_l9r_go_relaxed.owl	downregulation of membrane potential|down regulation of membrane potential|reduction of membrane potential|inhibition of membrane potential|down-regulation of membrane potential													biological_process											owl:Class	
GO:1901610	biolink:NamedThing	positive regulation of vesicle transport along microtubule	Any process that activates or increases the frequency, rate or extent of vesicle transport along microtubule.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of microtubule-based vesicle localization|up regulation of microtubule-based vesicle localization|activation of microtubule-based vesicle localization|upregulation of microtubule-based vesicle localization|up-regulation of microtubule-based vesicle localization|activation of vesicle transport along microtubule|up-regulation of vesicle transport along microtubule|upregulation of vesicle transport along microtubule|up regulation of vesicle transport along microtubule							hjd	2012-11-08T21:49:53Z					biological_process											owl:Class	
GO:1901608	biolink:NamedThing	regulation of vesicle transport along microtubule	Any process that modulates the frequency, rate or extent of vesicle transport along microtubule.	tmpzr1t_l9r_go_relaxed.owl	regulation of microtubule-based vesicle localization							hjd	2012-11-08T21:49:44Z					biological_process											owl:Class	
GO:1905574	biolink:NamedThing	ganglioside GM2 binding	Binding to ganglioside GM2.	tmpzr1t_l9r_go_relaxed.owl								pga	2016-10-19T11:17:01Z					molecular_function											owl:Class	
GO:1990615	biolink:NamedThing	Kelch-containing formin regulatory complex	A protein complex that regulates actin cable formation, polarized cell growth, and cytokinesis in a formin-dependent manner. In S. cerevisiae the complex is composed of Bud14p and two Kelch family proteins, Kel1p and Kel2p.	tmpzr1t_l9r_go_relaxed.owl	KFRC complex|Bud14-Kel1-Kel2 complex							mcc	2015-01-21T18:48:51Z					cellular_component											owl:Class	
GO:0019982	biolink:NamedThing	interleukin-7 binding	Binding to interleukin-7.	tmpzr1t_l9r_go_relaxed.owl	IL-7 binding													molecular_function											owl:Class	
GO:0016474	biolink:NamedThing	sodium ion-transporting V-type ATPase complex	A sodium ion-transporting two-sector ATPase complex that couples ATP hydrolysis to the transport of sodium ions across a concentration gradient. The complex comprises a membrane sector (V0) that carries out proton transport and a cytoplasmic compartment sector (V1) that catalyzes ATP hydrolysis.	tmpzr1t_l9r_go_relaxed.owl	sodium-translocating V-type ATPase complex													cellular_component											owl:Class	
GO:0016472	biolink:NamedThing	sodium ion-transporting two-sector ATPase complex	A large protein complex that catalyzes the synthesis or hydrolysis of ATP by a rotational mechanism, coupled to the transport of sodium ions across a membrane. The complex comprises a membrane sector (F0 or V0) that carries out ion transport and a cytoplasmic compartment sector (F1 or V1) that catalyzes ATP synthesis or hydrolysis.	tmpzr1t_l9r_go_relaxed.owl	sodium-transporting two-sector ATPase complex													cellular_component											owl:Class	
GO:0046888	biolink:NamedThing	negative regulation of hormone secretion	Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a hormone from a cell.	tmpzr1t_l9r_go_relaxed.owl	down regulation of hormone secretion|down-regulation of hormone secretion|inhibition of hormone secretion|downregulation of hormone secretion													biological_process											owl:Class	
GO:0005161	biolink:NamedThing	platelet-derived growth factor receptor binding	Binding to a platelet-derived growth factor receptor.	tmpzr1t_l9r_go_relaxed.owl	platelet-derived growth factor receptor ligand|PDGF|PDGFR binding|PDGF receptor binding|platelet-derived growth factor													molecular_function											owl:Class	
GO:0070535	biolink:NamedThing	histone H2A K63-linked ubiquitination	A histone ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 63 of the ubiquitin monomers, is added to a lysine residue in histone H2A or the variant H2AX.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0033522	biolink:NamedThing	histone H2A ubiquitination	The modification of histone H2A by addition of one or more ubiquitin groups.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0061310	biolink:NamedThing	canonical Wnt signaling pathway involved in cardiac neural crest cell differentiation involved in heart development	The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes involved in cardiac neural crest cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	canonical Wnt receptor signalling pathway involved in cardiac neural crest cell differentiation involved in heart development|canonical Wnt receptor signaling pathway involved in cardiac neural crest cell differentiation involved in heart development|canonical Wnt-activated signaling pathway involved in cardiac neural crest cell differentiation involved in heart development							dph	2010-09-23T09:12:36Z					biological_process											owl:Class	
GO:0044335	biolink:NamedThing	canonical Wnt signaling pathway involved in neural crest cell differentiation	The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes involved in neural crest cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	canonical Wnt receptor signaling pathway involved in neural crest cell differentiation|canonical Wnt receptor signalling pathway involved in neural crest cell differentiation|canonical Wnt-activated signaling pathway involved in neural crest cell differentiation							jl	2010-08-20T03:02:34Z					biological_process											owl:Class	
GO:0009374	biolink:NamedThing	biotin binding	Binding to biotin (cis-tetrahydro-2-oxothieno(3,4-d)imidazoline-4-valeric acid), the (+) enantiomer of which is very widely distributed in cells and serves as a carrier in a number of enzymatic beta-carboxylation reactions.	tmpzr1t_l9r_go_relaxed.owl	vitamin H binding|vitamin B7 binding													molecular_function											owl:Class	
GO:1901201	biolink:NamedThing	regulation of extracellular matrix assembly	Any process that modulates the frequency, rate or extent of extracellular matrix assembly.	tmpzr1t_l9r_go_relaxed.owl								rl	2012-07-27T04:04:00Z					biological_process											owl:Class	
GO:0060974	biolink:NamedThing	cell migration involved in heart formation	The orderly movement of a cell from one site to another that contribute to the formation of the heart. The initial heart structure is made up of mesoderm-derived heart progenitor cells and neural crest-derived cells.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-10-06T10:56:33Z					biological_process											owl:Class	
GO:1904333	biolink:NamedThing	positive regulation of error-prone translesion synthesis	Any process that activates or increases the frequency, rate or extent of error-prone translesion synthesis.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of mutagenic PRR|up regulation of mutagenic postreplication DNA repair|positive regulation of error-prone postreplication DNA repair|positive regulation of mutagenic PRR|activation of error-prone translesion synthesis|upregulation of mutagenic postreplication DNA repair|upregulation of mutagenic PRR|up regulation of error-prone translesion synthesis|upregulation of error-prone postreplication DNA repair|activation of mutagenic PRR|activation of mutagenic postreplication DNA repair|up-regulation of mutagenic postreplication DNA repair|upregulation of error-prone translesion synthesis|up-regulation of error-prone translesion synthesis|positive regulation of mutagenic postreplication DNA repair|up regulation of mutagenic PRR|up-regulation of error-prone postreplication DNA repair|activation of error-prone postreplication DNA repair|up regulation of error-prone postreplication DNA repair							kmv	2015-06-11T16:25:10Z					biological_process											owl:Class	
GO:0045739	biolink:NamedThing	positive regulation of DNA repair	Any process that activates or increases the frequency, rate or extent of DNA repair.	tmpzr1t_l9r_go_relaxed.owl	up regulation of DNA repair|stimulation of DNA repair|activation of DNA repair|upregulation of DNA repair|up-regulation of DNA repair													biological_process											owl:Class	
GO:0033902	biolink:NamedThing	rRNA endonuclease activity	Catalysis of the hydrolysis of the phosphodiester linkage between guanosine and adenosine residues at one specific position in 28S rRNA from rat ribosomes.	tmpzr1t_l9r_go_relaxed.owl	alpha-sarcin				MetaCyc:3.1.27.10-RXN|EC:4.6.1.23									molecular_function											owl:Class	
GO:0009223	biolink:NamedThing	pyrimidine deoxyribonucleotide catabolic process	The chemical reactions and pathways resulting in the breakdown of a pyrimidine deoxyribonucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.	tmpzr1t_l9r_go_relaxed.owl	pyrimidine deoxyribonucleotide breakdown|pyrimidine deoxyribonucleotide degradation|pyrimidine deoxyribonucleotide catabolism													biological_process											owl:Class	
GO:0046386	biolink:NamedThing	deoxyribose phosphate catabolic process	The chemical reactions and pathways resulting in the breakdown of deoxyribose phosphate, the phosphorylated sugar 2-deoxy-erythro-pentose.	tmpzr1t_l9r_go_relaxed.owl	deoxyribose phosphate catabolism|deoxyribose phosphate breakdown|deoxyribose phosphate degradation													biological_process											owl:Class	
GO:0098773	biolink:NamedThing	skin epidermis development	The process whose specific outcome is the progression of the skin epidermis over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0008544	biolink:NamedThing	epidermis development	The process whose specific outcome is the progression of the epidermis over time, from its formation to the mature structure. The epidermis is the outer epithelial layer of an animal, it may be a single layer that produces an extracellular material (e.g. the cuticle of arthropods) or a complex stratified squamous epithelium, as in the case of many vertebrate species.	tmpzr1t_l9r_go_relaxed.owl	hypodermis development													biological_process											owl:Class	
GO:0001411	biolink:NamedThing	hyphal tip	The end, or tip, of a fungal hypha, where polarized growth occurs during hyphal elongation.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0140338	biolink:NamedThing	sphingomyelin transfer activity	Removes a sphingomyelin from the outer leaflet of a donor membrane, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to the outer leaflet of an acceptor membrane.	tmpzr1t_l9r_go_relaxed.owl	sphingomyelin carrier activity|sphingosine transmembrane transporter activity							pg	2019-05-16T11:31:58Z			GO:0010175		molecular_function											owl:Class	
GO:0120014	biolink:NamedThing	phospholipid transfer activity	Removes a phospholipid from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle.	tmpzr1t_l9r_go_relaxed.owl	intermembrane phospholipid transfer activity|phospholipid carrier activity	https://github.com/geneontology/go-ontology/issues/12329						krc	2017-03-17T03:34:17Z					molecular_function											owl:Class	
GO:0046345	biolink:NamedThing	abscisic acid catabolic process	The chemical reactions and pathways resulting in the breakdown of abscisic acid, 5-(1-hydroxy-2,6,6,trimethyl-4-oxocyclohex-2-en-1-y1)-3-methylpenta-2,4-dienoic acid.	tmpzr1t_l9r_go_relaxed.owl	abscisic acid degradation|abscisic acid catabolism|abscisic acid breakdown													biological_process											owl:Class	
GO:0043290	biolink:NamedThing	apocarotenoid catabolic process	The chemical reactions and pathways resulting in the breakdown of apocarotenoids, a class of compounds derived from the oxidative cleavage of carotenoids, many of which are biologically important e.g. retinal and abscisic acid.	tmpzr1t_l9r_go_relaxed.owl	apo carotenoid catabolic process|apocarotenoid catabolism|apocarotenoid degradation|apocarotenoid breakdown													biological_process											owl:Class	
GO:1904445	biolink:NamedThing	negative regulation of establishment of Sertoli cell barrier	Any process that stops, prevents or reduces the frequency, rate or extent of establishment of Sertoli cell barrier.	tmpzr1t_l9r_go_relaxed.owl	downregulation of establishment of Sertoli cell barrier|downregulation of establishment of SCB|inhibition of establishment of blood-testis barrier|down-regulation of establishment of Sertoli cell barrier|downregulation of establishment of BTB|negative regulation of establishment of SCB|negative regulation of establishment of BTB|down regulation of establishment of Sertoli cell barrier|inhibition of establishment of BTB|down-regulation of establishment of SCB|negative regulation of establishment of blood-testis barrier|inhibition of establishment of Sertoli cell barrier|down regulation of establishment of blood-testis barrier|down-regulation of establishment of blood-testis barrier|down regulation of establishment of BTB|inhibition of establishment of SCB|downregulation of establishment of blood-testis barrier|down regulation of establishment of SCB|down-regulation of establishment of BTB							sl	2015-07-06T16:00:48Z					biological_process											owl:Class	
GO:0039690	biolink:NamedThing	positive stranded viral RNA replication	A viral genome replication process where the template genome is positive stranded, single stranded RNA ((+)ssRNA). Replication of the positive strand leads to dsRNA formation, which in turn is transcribed into positive single stranded RNA.	tmpzr1t_l9r_go_relaxed.owl	ss(+) viral RNA replication				VZ:1116			bf	2013-10-17T15:45:40Z					biological_process											owl:Class	
GO:0039694	biolink:NamedThing	viral RNA genome replication	The replication of a viral RNA genome.	tmpzr1t_l9r_go_relaxed.owl								bf	2013-10-23T15:24:36Z					biological_process											owl:Class	
GO:0034133	biolink:NamedThing	positive regulation of toll-like receptor 1 signaling pathway	Any process that activates or increases the frequency, rate, or extent of toll-like receptor 1 signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of TLR1 signaling pathway|positive regulation of toll-like receptor 1 signalling pathway													biological_process											owl:Class	
GO:0035100	biolink:NamedThing	ecdysone binding	Binding to 20-hydroxyecdysone (ecdysone). Ecdysone is an ecdysteroid produced by the prothoracic glands of immature insects and the ovaries of adult females, which stimulates growth and molting.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0043590	biolink:NamedThing	bacterial nucleoid	The region of a bacterial cell to which the DNA is confined.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:1904150	biolink:NamedThing	negative regulation of microglial cell mediated cytotoxicity	Any process that stops, prevents or reduces the frequency, rate or extent of microglial cell mediated cytotoxicity.	tmpzr1t_l9r_go_relaxed.owl	down regulation of microglial cell mediated cytotoxicity|inhibition of microglial cell mediated cytotoxicity|downregulation of microglial cell mediated cytotoxicity|down-regulation of microglial cell mediated cytotoxicity							nc	2015-04-15T08:05:35Z					biological_process											owl:Class	
GO:0001911	biolink:NamedThing	negative regulation of leukocyte mediated cytotoxicity	Any process that stops, prevents, or reduces the rate of leukocyte mediated cytotoxicity.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of immune cell mediated cytotoxicity|negative regulation of leucocyte mediated cytotoxicity|inhibition of leukocyte mediated cytotoxicity|downregulation of leukocyte mediated cytotoxicity|down-regulation of leukocyte mediated cytotoxicity|down regulation of leukocyte mediated cytotoxicity													biological_process											owl:Class	
GO:0010666	biolink:NamedThing	positive regulation of cardiac muscle cell apoptotic process	Any process that increases the rate or extent of cardiac cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a cardiac muscle cell and result in its death.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of cardiac muscle cell apoptosis													biological_process											owl:Class	
GO:0010663	biolink:NamedThing	positive regulation of striated muscle cell apoptotic process	Any process that increases the rate or extent of striated muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a striated muscle cell and result in its death.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of striated muscle cell apoptosis													biological_process											owl:Class	
GO:0003204	biolink:NamedThing	cardiac skeleton development	The progression of the cardiac skeleton over time, from its formation to the mature structure. The cardiac skeleton is a specialized extracellular matrix that separates the atria from the ventricles and provides physical support for the heart.	tmpzr1t_l9r_go_relaxed.owl	heart fibrous skeleton development							dph	2009-10-13T09:05:04Z					biological_process											owl:Class	
GO:0004603	biolink:NamedThing	phenylethanolamine N-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + phenylethanolamine = S-adenosyl-L-homocysteine + N-methylphenylethanolamine.	tmpzr1t_l9r_go_relaxed.owl	norepinephrine N-methyltransferase activity|noradrenalin N-methyltransferase activity|noradrenaline N-methyltransferase activity|phenethanolamine methyltransferase activity|phenethanolamine N-methyltransferase activity|S-adenosyl-L-methionine:phenylethanolamine N-methyltransferase activity|norepinephrine methyltransferase activity				MetaCyc:2.1.1.28-RXN|EC:2.1.1.28|RHEA:12176|Reactome:R-HSA-209903									molecular_function											owl:Class	
GO:0000930	biolink:NamedThing	gamma-tubulin complex	A multiprotein complex composed of gamma-tubulin and other non-tubulin proteins. Gamma-tubulin complexes are localized to microtubule organizing centers, and play an important role in the nucleation of microtubules. The number and complexity of non-tubulin proteins associated with these complexes varies between species.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0016696	biolink:NamedThing	oxidoreductase activity, acting on hydrogen as donor, NAD or NADP as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which hydrogen acts as an electron donor and reduces NAD or NADP.	tmpzr1t_l9r_go_relaxed.owl					EC:1.12.1.-									molecular_function											owl:Class	
GO:0016695	biolink:NamedThing	oxidoreductase activity, acting on hydrogen as donor	Catalysis of an oxidation-reduction (redox) reaction in which hydrogen acts as an electron donor.	tmpzr1t_l9r_go_relaxed.owl	oxidoreductase activity, acting on hydrogen as donor, other acceptors				EC:1.12.-.-									molecular_function											owl:Class	
GO:0140030	biolink:NamedThing	modification-dependent protein binding	Binding to a protein upon post-translation modification of the target protein.	tmpzr1t_l9r_go_relaxed.owl	modified protein binding					This term should only be used when the binding is shown to require a post-translational modification: the interaction needs to be tested with and without the PTM. The binding does not need to be at the site of the modification. It may be that the PTM causes a conformational change that allows binding of the protein to another region; this type of modification-dependent protein binding is valid for annotation to this term.		pg	2017-05-17T11:50:41Z					molecular_function											owl:Class	
GO:1903226	biolink:NamedThing	positive regulation of endodermal cell differentiation	Any process that activates or increases the frequency, rate or extent of endodermal cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of endodermal cell differentiation|activation of endoderm cell differentiation|up-regulation of endoderm cell differentiation|up regulation of endodermal cell differentiation|positive regulation of endoderm cell differentiation|upregulation of endoderm cell differentiation|up regulation of endoderm cell differentiation|upregulation of endodermal cell differentiation|activation of endodermal cell differentiation							als	2014-07-29T13:22:47Z					biological_process											owl:Class	
GO:1903224	biolink:NamedThing	regulation of endodermal cell differentiation	Any process that modulates the frequency, rate or extent of endodermal cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	regulation of endoderm cell differentiation							als	2014-07-29T13:22:35Z					biological_process											owl:Class	
GO:0060669	biolink:NamedThing	embryonic placenta morphogenesis	The process in which the embryonic placenta is generated and organized.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-06-02T09:33:37Z					biological_process											owl:Class	
GO:0072553	biolink:NamedThing	terminal button organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a terminal button. A terminal button is the terminal inflated portion of the axon, containing the specialized apparatus necessary to release neurotransmitters.	tmpzr1t_l9r_go_relaxed.owl	synaptic bouton organization|presynaptic bouton organization|terminal bouton organization|terminal button organisation|bouton organization							mah	2011-01-25T04:09:35Z					biological_process											owl:Class	
GO:0050145	biolink:NamedThing	nucleoside monophosphate kinase activity	Catalysis of the reaction: ATP + nucleoside monophosphate = ADP + nucleoside diphosphate.	tmpzr1t_l9r_go_relaxed.owl	ATP:nucleoside-phosphate phosphotransferase activity|nucleotide kinase activity|NMP-kinase activity|nucleoside-phosphate kinase activity				Reactome:R-HSA-75126|Reactome:R-HSA-73635|Reactome:R-HSA-2162092|MetaCyc:NUCLEOSIDE-PHOSPHATE-KINASE-RXN|Reactome:R-HSA-75125|Reactome:R-HSA-6788810|EC:2.7.4.4|Reactome:R-HSA-73548|Reactome:R-HSA-6788798|RHEA:24036							GO:0019201		molecular_function											owl:Class	
GO:0008315	biolink:NamedThing	G2/MI transition of meiotic cell cycle	The cell cycle process in which a cell progresses from meiotic G2 phase to M phase of meiosis I.	tmpzr1t_l9r_go_relaxed.owl	meiotic G2/MI phase transition|meiotic cell cycle G2/MI phase transition|meiotic G2/MI transition													biological_process											owl:Class	
GO:0044839	biolink:NamedThing	cell cycle G2/M phase transition	The cell cycle process by which a cell in G2 phase commits to M phase.	tmpzr1t_l9r_go_relaxed.owl								jl	2014-03-05T14:56:45Z					biological_process											owl:Class	
GO:0072248	biolink:NamedThing	metanephric glomerular visceral epithelial cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a metanephric glomerular visceral epithelial cell. A metanephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the metanephros.	tmpzr1t_l9r_go_relaxed.owl	metanephric podocyte differentiation							mah	2010-03-19T03:44:57Z					biological_process											owl:Class	
GO:1901091	biolink:NamedThing	negative regulation of protein tetramerization	Any process that stops, prevents or reduces the frequency, rate or extent of protein tetramerization.	tmpzr1t_l9r_go_relaxed.owl	inhibition of protein tetramer formation|inhibition of protein tetramer biosynthetic process|downregulation of protein tetramer assembly|down-regulation of protein tetramerization|downregulation of protein tetramer biosynthesis|down-regulation of protein tetramer assembly|down regulation of protein tetramer assembly|down-regulation of protein tetramer biosynthesis|inhibition of protein tetramer assembly|negative regulation of protein tetramer assembly|down regulation of protein tetramer biosynthetic process|inhibition of protein tetramer biosynthesis|down regulation of protein tetramer formation|down regulation of protein tetramer biosynthesis|down regulation of protein tetramerization|down-regulation of protein tetramer biosynthetic process|downregulation of protein tetramerization|negative regulation of protein tetramer formation|negative regulation of protein tetramer biosynthetic process|downregulation of protein tetramer biosynthetic process|downregulation of protein tetramer formation|negative regulation of protein tetramer biosynthesis|inhibition of protein tetramerization|down-regulation of protein tetramer formation							pm	2012-07-06T12:51:24Z					biological_process											owl:Class	
GO:0032460	biolink:NamedThing	negative regulation of protein oligomerization	Any process that stops, prevents, or reduces the frequency, rate or extent of protein oligomerization.	tmpzr1t_l9r_go_relaxed.owl	down regulation of protein oligomerization|down-regulation of protein oligomerization|downregulation of protein oligomerization|inhibition of protein oligomerization													biological_process											owl:Class	
GO:1990701	biolink:NamedThing	integral component of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane	The component of the ERGIC membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.	tmpzr1t_l9r_go_relaxed.owl	integral component of ERGIC membrane|integral component of ER-Golgi intermediate compartment membrane|integral component of endoplasmic reticulum-Golgi intermediate compartment membrane							bhm	2015-03-16T15:57:36Z					cellular_component											owl:Class	
GO:0080089	biolink:NamedThing	sinapoyl spermidine:sinapoyl CoA N-acyltransferase activity	Catalysis of the transfer of a sinapoyl group to a nitrogen atom on a sinapoyl spermidine molecule resulting in the formation of a disinapoyl spermidine derivative.	tmpzr1t_l9r_go_relaxed.owl								dhl	2009-04-22T03:27:55Z					molecular_function											owl:Class	
GO:1900489	biolink:NamedThing	positive regulation of [2Fe-2S] cluster assembly	Any process that activates or increases the frequency, rate or extent of [2Fe-2S] cluster assembly.	tmpzr1t_l9r_go_relaxed.owl	activation of 2Fe-2S cluster assembly|upregulation of [2Fe-2S] cluster assembly|upregulation of [2Fe-2S] cluster biosynthetic process|up regulation of [2Fe-2S] cluster biosynthetic process|upregulation of 2Fe-2S cluster assembly|positive regulation of [2Fe-2S] cluster biosynthetic process|up-regulation of 2Fe-2S cluster assembly|up regulation of 2Fe-2S cluster assembly|up-regulation of [2Fe-2S] cluster assembly|activation of [2Fe-2S] cluster assembly|activation of [2Fe-2S] cluster biosynthetic process|up regulation of [2Fe-2S] cluster assembly|positive regulation of 2Fe-2S cluster assembly|up-regulation of [2Fe-2S] cluster biosynthetic process							tt	2012-05-02T01:22:40Z					biological_process											owl:Class	
GO:0031991	biolink:NamedThing	regulation of actomyosin contractile ring contraction	Any process that modulates the frequency, rate or extent of contraction of the actomyosin ring involved in cytokinesis that takes place as part of a cell cycle.	tmpzr1t_l9r_go_relaxed.owl	regulation of contractile ring contraction involved in cytokinesis during cell cycle|regulation of contractile ring contraction involved in cell cycle cytokinesis|regulation of actomyosin contractile ring constriction	https://github.com/geneontology/go-ontology/issues/21855												biological_process											owl:Class	
GO:0006214	biolink:NamedThing	thymidine catabolic process	The chemical reactions and pathways resulting in the breakdown of thymidine, deoxyribosylthymine thymine 2-deoxyriboside, a deoxynucleoside very widely distributed but occurring almost entirely as phosphoric esters in deoxynucleotides and deoxyribonucleic acid, DNA.	tmpzr1t_l9r_go_relaxed.owl	thymidine catabolism|deoxyribosylthymine catabolic process|deoxyribosylthymine catabolism|thymidine breakdown|thymidine degradation											GO:0006215		biological_process											owl:Class	
GO:0046104	biolink:NamedThing	thymidine metabolic process	The chemical reactions and pathways involving thymidine, deoxyribosylthymine thymine 2-deoxyriboside, a deoxynucleoside very widely distributed but occurring almost entirely as phosphoric esters in deoxynucleotides and deoxyribonucleic acid, DNA.	tmpzr1t_l9r_go_relaxed.owl	deoxyribosylthymine metabolic process|thymidine metabolism|deoxyribosylthymine metabolism													biological_process											owl:Class	
GO:0046278	biolink:NamedThing	3,4-dihydroxybenzoate metabolic process	The chemical reactions and pathways involving protocatechuate, the anion of protocatechuic acid (3,4-dihydroxybenzoic acid).	tmpzr1t_l9r_go_relaxed.owl	protocatechuate metabolic process|protocatechuate metabolism													biological_process											owl:Class	
GO:1904460	biolink:NamedThing	positive regulation of substance P secretion	Any process that activates or increases the frequency, rate or extent of substance P secretion.	tmpzr1t_l9r_go_relaxed.owl	up regulation of substance P secretion|activation of substance P secretion|upregulation of substance P secretion|up-regulation of substance P secretion							sl	2015-07-09T19:33:03Z					biological_process											owl:Class	
GO:0031568	biolink:NamedThing	mitotic G1 cell size control checkpoint signaling	A signal transduction process that contributes to a cell size control checkpoint during the G1/S transition of the cell cycle.	tmpzr1t_l9r_go_relaxed.owl	mitotic G1 cell size control checkpoint|signal transduction involved in mitotic cell cycle G1/S transition size control checkpoint|mitotic cell cycle G1/S transition size control checkpoint|G1 cell size control checkpoint signalling|G1 cell size control checkpoint|signal transduction involved in G1 cell size control checkpoint											GO:0072450		biological_process											owl:Class	
GO:0089714	biolink:NamedThing	UDP-N-acetyl-D-mannosamine dehydrogenase activity	Catalysis of the reaction: UDP-N-acetyl-alpha-D-mannosamine + 2 NAD+ + H2O = UDP-N-acetyl-alpha-D-mannosaminuronate + 2 NADH + 2 H+.	tmpzr1t_l9r_go_relaxed.owl					EC:1.1.1.336|RHEA:25780									molecular_function											owl:Class	
GO:0097576	biolink:NamedThing	vacuole fusion	Merging of two or more vacuoles, or of vacuoles and vesicles within a cell to form a single larger vacuole.	tmpzr1t_l9r_go_relaxed.owl								pr	2014-02-28T09:49:31Z					biological_process											owl:Class	
GO:0007033	biolink:NamedThing	vacuole organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a vacuole.	tmpzr1t_l9r_go_relaxed.owl	vacuole biogenesis|vacuolar assembly|vacuole organization and biogenesis|vacuole organisation											GO:0044086		biological_process											owl:Class	
GO:0007175	biolink:NamedThing	negative regulation of epidermal growth factor-activated receptor activity	Any process that stops, prevents, or reduces the frequency, rate or extent of EGF-activated receptor activity.	tmpzr1t_l9r_go_relaxed.owl	EGF receptor downregulation|negative regulation of EGFR activity|negative regulation of epidermal growth factor receptor activity|down-regulation of epidermal growth factor receptor activity|inhibition of epidermal growth factor receptor activity|negative regulation of EGF receptor activity|down regulation of epidermal growth factor receptor activity|downregulation of epidermal growth factor receptor activity											GO:0007177		biological_process											owl:Class	
GO:0034608	biolink:NamedThing	vulval location	Location, by the male, of his partner's vulva when backing along the ventral side of the hermaphrodite during mating. The male stops at the vulva, coordinates his movements to the hermaphrodite's, and positions his tail precisely over the vulva so that he may insert his spicules and ejaculate.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0060179	biolink:NamedThing	male mating behavior	The specific behavior of a male organism that is associated with reproduction.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0048650	biolink:NamedThing	caste determination, influence by environmental factors	The process in which individuals, having the potential to develop any of several distinct developmental paths, have their individual developmental fate determined in response to environmental cues. Individuals with distinct developmental fates perform different functions in a colony of social insects.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0048651	biolink:NamedThing	polyphenic determination, influence by environmental factors	The process in which individuals that have the potential to develop any of several possible distinct developmental paths have their individual developmental fates determined in response to environmental cues.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0099645	biolink:NamedThing	neurotransmitter receptor localization to postsynaptic specialization membrane	A process in which a neurotransmitter is transported to, or maintained in, a location within the membrane adjacent to a postsynaptic specialization (e.g. postsynaptic density).	tmpzr1t_l9r_go_relaxed.owl	neurotransmitter receptor localisation in postsynaptic specialization membrane													biological_process											owl:Class	
GO:0099633	biolink:NamedThing	protein localization to postsynaptic specialization membrane	A process in which a protein is transported to, or maintained in, a location within the membrane adjacent to a postsynaptic specialization (e.g. post synaptic density).	tmpzr1t_l9r_go_relaxed.owl	protein localisation in postsynaptic specialization membrane													biological_process											owl:Class	
GO:0033958	biolink:NamedThing	DNA-deoxyinosine glycosylase activity	Catalysis of the hydrolysis of DNA and polynucleotides, releasing free hypoxanthine.	tmpzr1t_l9r_go_relaxed.owl	DNA(hypoxanthine) glycohydrolase activity|hypoxanthine-DNA glycosylase activity|deoxyribonucleic acid glycosylase activity|DNA-deoxyinosine deoxyribohydrolase activity|DNA-deoxyinosine glycosidase activity				MetaCyc:3.2.2.15-RXN|EC:3.2.2.15									molecular_function											owl:Class	
GO:0046671	biolink:NamedThing	negative regulation of retinal cell programmed cell death	Any process that stops, prevents, or reduces the frequency, rate or extent of programmed cell death that occurs in the retina.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of retinal programmed cell death|inhibition of retinal programmed cell death|downregulation of retinal programmed cell death|down regulation of retinal programmed cell death|negative regulation of retinal programmed cell death													biological_process											owl:Class	
GO:0140250	biolink:NamedThing	regulation protein catabolic process at synapse	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein at the synapse.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/synapse/issues/204				Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.		pg	2018-07-15T10:34:56Z					biological_process											owl:Class	
GO:0009894	biolink:NamedThing	regulation of catabolic process	Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of substances.	tmpzr1t_l9r_go_relaxed.owl	regulation of catabolism|regulation of degradation|regulation of breakdown													biological_process											owl:Class	
GO:1902465	biolink:NamedThing	negative regulation of histone H3-K27 trimethylation	Any process that stops, prevents or reduces the frequency, rate or extent of histone H3-K27 trimethylation.	tmpzr1t_l9r_go_relaxed.owl	downregulation of histone H3-K27 trimethylation|down regulation of histone H3-K27 trimethylation|inhibition of histone H3-K27 trimethylation|down-regulation of histone H3-K27 trimethylation							krc	2013-10-22T14:59:04Z					biological_process											owl:Class	
GO:0061086	biolink:NamedThing	negative regulation of histone H3-K27 methylation	Any process that decreases the rate, frequency, or extent of histone H3-K27 methylation. Histone H3-K27 methylation is the modification of histone H3 by addition of a methyl group to lysine at position 27 of the histone.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-04-26T01:23:52Z					biological_process											owl:Class	
GO:0050783	biolink:NamedThing	cocaine metabolic process	The chemical reactions and pathways involving cocaine, an alkaloid obtained from the dried leaves of the shrub Erythroxylon coca. It is a cerebral stimulant and narcotic.	tmpzr1t_l9r_go_relaxed.owl	cocaine metabolism													biological_process											owl:Class	
GO:1905227	biolink:NamedThing	negative regulation of adhesion of symbiont to host epithelial cell	Any process that stops, prevents or reduces the frequency, rate or extent of adhesion of symbiont to host epithelial cell.	tmpzr1t_l9r_go_relaxed.owl	inhibition of adhesion of symbiont to host epithelial cell|downregulation of adhesion of symbiont to host epithelial cell|down-regulation of adhesion of symbiont to host epithelial cell|down regulation of adhesion of symbiont to host epithelial cell							pga	2016-06-07T13:15:16Z					biological_process											owl:Class	
GO:0048147	biolink:NamedThing	negative regulation of fibroblast proliferation	Any process that stops, prevents, or reduces the frequency, rate or extent of multiplication or reproduction of fibroblast cells.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of fibroblast proliferation|down regulation of fibroblast proliferation|inhibition of fibroblast proliferation|downregulation of fibroblast proliferation													biological_process											owl:Class	
GO:1903780	biolink:NamedThing	negative regulation of cardiac conduction	Any process that stops, prevents or reduces the frequency, rate or extent of cardiac conduction.	tmpzr1t_l9r_go_relaxed.owl	inhibition of cardiac conduction|downregulation of cardiac conduction|down regulation of cardiac conduction|down-regulation of cardiac conduction							rph	2015-01-07T13:20:20Z					biological_process											owl:Class	
GO:2001280	biolink:NamedThing	positive regulation of unsaturated fatty acid biosynthetic process	Any process that activates or increases the frequency, rate or extent of unsaturated fatty acid biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of unsaturated fatty acid anabolism|positive regulation of polyunsaturated fatty acid biosynthesis|positive regulation of unsaturated fatty acid biosynthesis|positive regulation of unsaturated fatty acid formation|positive regulation of fatty acid desaturation|positive regulation of unsaturated fatty acid synthesis							dgf	2011-12-14T07:48:33Z					biological_process											owl:Class	
GO:0003910	biolink:NamedThing	DNA ligase (ATP) activity	Catalysis of the reaction: ATP + deoxyribonucleotide(n) + deoxyribonucleotide(m) = AMP + diphosphate + deoxyribonucleotide(n+m).	tmpzr1t_l9r_go_relaxed.owl	DNA repair enzyme activity|deoxyribonucleic joinase|deoxyribonucleate ligase|deoxyribonucleic repair enzyme|deoxyribonucleic-joining enzyme|DNA joinase activity|deoxyribonucleic acid-joining enzyme|polydeoxyribonucleotide synthase (ATP) activity|deoxyribonucleic acid repair enzyme|poly(deoxyribonucleotide):poly(deoxyribonucleotide) ligase (AMP-forming)|deoxyribonucleic acid joinase|polynucleotide ligase (ATP) activity|polynucleotide ligase|sealase activity|deoxyribonucleic acid ligase|DNA-joining enzyme|deoxyribonucleic ligase				EC:6.5.1.1|MetaCyc:DNA-LIGASE-ATP-RXN									molecular_function											owl:Class	
GO:0003909	biolink:NamedThing	DNA ligase activity	Catalysis of the formation of a phosphodiester bond between the 3'-hydroxyl group at the end of one DNA chain and the 5'-phosphate group at the end of another. This reaction requires an energy source such as ATP or NAD+.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-5690997|Reactome:R-HSA-5651805|Reactome:R-HSA-175258|Reactome:R-HSA-73931|Reactome:R-HSA-174456|Reactome:R-HSA-5693604|Reactome:R-HSA-5649734|Reactome:R-HSA-5651789|Reactome:R-HSA-6782227|Reactome:R-HSA-5358592|Reactome:R-HSA-5687675|Reactome:R-HSA-69173									molecular_function											owl:Class	
GO:0046986	biolink:NamedThing	negative regulation of hemoglobin biosynthetic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hemoglobin, an oxygen carrying, conjugated protein containing four heme groups and globin.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of hemoglobin anabolism|negative regulation of hemoglobin biosynthesis|down regulation of hemoglobin biosynthetic process|down-regulation of hemoglobin biosynthetic process|inhibition of hemoglobin biosynthetic process|downregulation of hemoglobin biosynthetic process|negative regulation of haemoglobin biosynthetic process|negative regulation of haemoglobin biosynthesis|negative regulation of hemoglobin synthesis|negative regulation of hemoglobin formation													biological_process											owl:Class	
GO:0002398	biolink:NamedThing	MHC class Ib protein complex assembly	The aggregation, arrangement and bonding together of a set of components to form an MHC class Ib protein complex. Class Ib here refers to non-classical class I molecules.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0002396	biolink:NamedThing	MHC protein complex assembly	The aggregation, arrangement and bonding together of a set of components to form an MHC protein complex.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0032918	biolink:NamedThing	spermidine acetylation	The modification of spermidine by addition of acetyl groups.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0008216	biolink:NamedThing	spermidine metabolic process	The chemical reactions and pathways involving spermidine, N-(3-aminopropyl)-1,4-diaminobutane.	tmpzr1t_l9r_go_relaxed.owl	spermidine metabolism													biological_process											owl:Class	
GO:0006658	biolink:NamedThing	phosphatidylserine metabolic process	The chemical reactions and pathways involving phosphatidylserines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of L-serine. They are important constituents of cell membranes.	tmpzr1t_l9r_go_relaxed.owl	phosphatidylserine metabolism													biological_process											owl:Class	
GO:0046869	biolink:NamedThing	iron incorporation into iron-sulfur cluster via tris-L-cysteinyl-L-aspartato diiron disulfide	The incorporation of iron into a 2Fe-2S iron-sulfur cluster via tris-L-cysteinyl-L-aspartato diiron disulfide.	tmpzr1t_l9r_go_relaxed.owl	iron incorporation into iron-sulphur cluster via tris-L-cysteinyl-L-aspartato diiron disulphide				RESID:AA0331									biological_process											owl:Class	
GO:0044665	biolink:NamedThing	MLL1/2 complex	A protein complex that can methylate lysine-4 of histone H3, and which contains either of the protein subunits MLL1 or MLL2 in human, or equivalent in other species.	tmpzr1t_l9r_go_relaxed.owl	Trx-containing complex							jl	2012-08-07T14:44:12Z					cellular_component											owl:Class	
GO:0140279	biolink:NamedThing	regulation of mitotic division septum assembly	Any process that modulates the frequency, rate or extent of mitotic division septum formation. Division septum formation is the assembly and arrangement of a septum that spans the plasma membrane interface between progeny cells following cytokinesis.	tmpzr1t_l9r_go_relaxed.owl	regulation of formation of division septum involved in mitotic cell cycle|regulation of septin assembly and septum formation involved in mitotic cell cycle|regulation of division septum formation involved in mitotic cell cycle|regulation of septin assembly and septum biosynthesis involved in mitotic cell cycle							pg	2018-10-08T09:55:51Z					biological_process											owl:Class	
GO:0015926	biolink:NamedThing	glucosidase activity	Catalysis of the hydrolysis of glucosyl compounds, substances containing a group derived from a cyclic form of glucose or a glucose derivative.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0019961	biolink:NamedThing	interferon binding	Binding to an interferon, a protein produced by the immune systems of many animals in response to a challenge by a foreign agent.	tmpzr1t_l9r_go_relaxed.owl	IFN binding													molecular_function											owl:Class	
GO:0030451	biolink:NamedThing	regulation of complement activation, alternative pathway	Any process that modulates the frequency, rate or extent of the alternative pathway of complement activation.	tmpzr1t_l9r_go_relaxed.owl	regulation of complement cascade, alternative pathway													biological_process											owl:Class	
GO:1990585	biolink:NamedThing	hydroxyproline O-arabinosyltransferase activity	Catalysis of the reaction: UDP-beta-L-arabinofuranose + a [protein]-trans-4-hydroxy-L-proline <=> a protein-O-(beta-L-arabinofuranose)-trans-4-hydroxy-L-proline + UDP + H+.	tmpzr1t_l9r_go_relaxed.owl	HPAT							tb	2014-12-12T18:22:20Z					molecular_function											owl:Class	
GO:1901768	biolink:NamedThing	carbapenem catabolic process	The chemical reactions and pathways resulting in the breakdown of carbapenem.	tmpzr1t_l9r_go_relaxed.owl	carbapenem breakdown|carbapenem degradation|carbapenem catabolism							yaf	2013-01-15T10:09:02Z					biological_process											owl:Class	
GO:1901767	biolink:NamedThing	carbapenem metabolic process	The chemical reactions and pathways involving carbapenem.	tmpzr1t_l9r_go_relaxed.owl	carbapenem metabolism							yaf	2013-01-15T10:08:57Z					biological_process											owl:Class	
GO:1900340	biolink:NamedThing	negative regulation of methane biosynthetic process from formic acid	Any process that stops, prevents or reduces the frequency, rate or extent of methane biosynthetic process from formic acid.	tmpzr1t_l9r_go_relaxed.owl	down regulation of methane biosynthetic process from formic acid|down-regulation of methane biosynthetic process from formic acid|inhibition of methane biosynthetic process from formic acid|downregulation of methane biosynthetic process from formic acid							tt	2012-04-06T02:05:03Z					biological_process											owl:Class	
GO:0036500	biolink:NamedThing	ATF6-mediated unfolded protein response	A series of molecular signals mediated by the endoplasmic reticulum membrane stress sensor ATF6 (activating transcription factor 6). Begins with activation of ATF6 in response to endoplasmic reticulum (ER) stress, and ends with regulation of a downstream cellular process, e.g. transcription. Under conditions of endoplasmic reticulum stress, ATF6 translocates to the Golgi where it is processed by proteases to release a cytoplasmic domain (ATF6f), which operates as a transcriptional activator of many genes required to restore folding capacity.	tmpzr1t_l9r_go_relaxed.owl	ATF6 branch of UPR|ATF6-beta UPR branch|activating transcription factor 6 signaling in unfolded protein response|endoplasmic reticulum unfolded protein response; ATF6 signaling|ATF6-alpha UPR branch|UPR signaling by ATF6 stress sensor|ATF6 signaling in response to endoplasmic reticulum stress|ATF6 signal transduction pathway							bf	2015-02-05T13:18:58Z					biological_process											owl:Class	
GO:0060278	biolink:NamedThing	regulation of ovulation	Any process that modulates the frequency, rate or extent of ovulation, the release of a mature ovum/oocyte from an ovary.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1903954	biolink:NamedThing	positive regulation of voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization	Any process that activates or increases the frequency, rate or extent of voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization.	tmpzr1t_l9r_go_relaxed.owl	activation of voltage-gated potassium channel activity involved in atrial cardiomyocyte action potential repolarization|upregulation of voltage-gated potassium channel activity involved in atrial cardiomyocyte action potential repolarization|up-regulation of voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization|positive regulation of voltage-gated potassium channel activity involved in atrial cardiomyocyte action potential repolarization|up-regulation of voltage-gated potassium channel activity involved in atrial cardiomyocyte action potential repolarization|upregulation of voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization|activation of voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization|up regulation of voltage-gated potassium channel activity involved in atrial cardiomyocyte action potential repolarization|up regulation of voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization							nc	2015-02-24T10:32:24Z					biological_process											owl:Class	
GO:0051796	biolink:NamedThing	negative regulation of timing of catagen	Any process that stops, prevents, or reduces the frequency, rate or extent of timing of catagen, the regression phase of the hair cycle.	tmpzr1t_l9r_go_relaxed.owl	downregulation of catagen|down regulation of catagen|inhibition of catagen|down-regulation of catagen|negative regulation of catagen													biological_process											owl:Class	
GO:0032049	biolink:NamedThing	cardiolipin biosynthetic process	The chemical reactions and pathways resulting in the formation of cardiolipin, 1,3-bis(3-phosphatidyl)glycerol.	tmpzr1t_l9r_go_relaxed.owl	diphosphatidylglycerol biosynthesis|diphosphatidylglycerol biosynthetic process				MetaCyc:PWY-5269									biological_process											owl:Class	
GO:0062212	biolink:NamedThing	regulation of mitotic DNA replication initiation from early origin	Any process that modulates the frequency, rate or extent of firing from an early origin of replication involved in mitotic DNA replication.	tmpzr1t_l9r_go_relaxed.owl	regulation of early replication origin firing							dph	2020-02-21T19:21:44Z					biological_process											owl:Class	
GO:0031357	biolink:NamedThing	integral component of chloroplast inner membrane	The component of the chloroplast inner membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.	tmpzr1t_l9r_go_relaxed.owl	integral to chloroplast inner membrane													cellular_component											owl:Class	
GO:0031353	biolink:NamedThing	integral component of plastid inner membrane	The component of the plastid inner membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.	tmpzr1t_l9r_go_relaxed.owl	integral to plastid inner membrane													cellular_component											owl:Class	
GO:1903661	biolink:NamedThing	positive regulation of complement-dependent cytotoxicity	Any process that activates or increases the frequency, rate or extent of complement-dependent cytotoxicity.	tmpzr1t_l9r_go_relaxed.owl	up regulation of complement-dependent cytotoxicity|activation of complement-dependent cytotoxicity|upregulation of complement-dependent cytotoxicity|up-regulation of complement-dependent cytotoxicity							jl	2014-11-25T15:04:11Z					biological_process											owl:Class	
GO:0031343	biolink:NamedThing	positive regulation of cell killing	Any process that activates or increases the frequency, rate or extent of cell killing.	tmpzr1t_l9r_go_relaxed.owl	upregulation of cell killing|up-regulation of cell killing|stimulation of cell killing|up regulation of cell killing|activation of cell killing													biological_process											owl:Class	
GO:0070720	biolink:NamedThing	Grb2-SHP-2 complex	A protein complex that contains the receptor adaptor proteins Grb2 and SHP-2, and is involved signaling via the PDGFR signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	GRB2-SHP-2 complex, PDGF stimulated							mah	2009-06-10T05:08:21Z					cellular_component											owl:Class	
GO:1902239	biolink:NamedThing	negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator	Any process that stops, prevents or reduces the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator|inhibition of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator|down regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator|downregulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator							pr	2013-06-19T14:00:39Z					biological_process											owl:Class	
GO:0004583	biolink:NamedThing	dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity	Catalysis of the transfer of an alpha-D-glucosyl residue from dolichyl-phosphate D-glucose into a membrane lipid-linked oligosaccharide.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-4724291|MetaCyc:RXN-5472|Reactome:R-HSA-446189|Reactome:R-HSA-446194|Reactome:R-HSA-4724330|Reactome:R-HSA-446202									molecular_function											owl:Class	
GO:0046527	biolink:NamedThing	glucosyltransferase activity	Catalysis of the transfer of a glucosyl group to an acceptor molecule, typically another carbohydrate or a lipid.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0089721	biolink:NamedThing	phosphoenolpyruvate transmembrane transporter activity	Enables the transfer of a phosphoenolpyruvate from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0015605	biolink:NamedThing	organophosphate ester transmembrane transporter activity	Enables the transfer of organophosphate esters from one side of a membrane to the other. Organophosphate esters are small organic molecules containing phosphate ester bonds.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0034224	biolink:NamedThing	cellular response to zinc ion starvation	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of zinc ions.	tmpzr1t_l9r_go_relaxed.owl	cellular response to zinc ion limitation|cellular response to zinc starvation													biological_process											owl:Class	
GO:0120127	biolink:NamedThing	response to zinc ion starvation	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of zinc ion.	tmpzr1t_l9r_go_relaxed.owl								krc	2018-02-12T19:57:02Z					biological_process											owl:Class	
GO:0004033	biolink:NamedThing	aldo-keto reductase (NADP) activity	Catalysis of the reaction: an alcohol + NADP+ = an aldehyde or a ketone + NADPH + H+.	tmpzr1t_l9r_go_relaxed.owl	aldo-keto reductase (NADP+) activity|NADPH-dependent aldo-keto reductase activity|aldo-keto reductase activity|alcohol dehydrogenase (NADP+) activity				Reactome:R-HSA-193755|Reactome:R-HSA-5423637|Reactome:R-HSA-9027600|Reactome:R-HSA-2855252|Reactome:R-HSA-192033|Reactome:R-HSA-193824|Reactome:R-HSA-193746|Reactome:R-HSA-9027598|Reactome:R-HSA-193781|Reactome:R-HSA-198845|Reactome:R-HSA-193821|Reactome:R-HSA-192067|Reactome:R-HSA-5692232|Reactome:R-HSA-193800|Reactome:R-HSA-193841|Reactome:R-HSA-9027562|Reactome:R-HSA-193758|Reactome:R-HSA-9027531|Reactome:R-HSA-192160|Reactome:R-HSA-192036									molecular_function											owl:Class	
GO:0045704	biolink:NamedThing	regulation of salivary gland boundary specification	Any process that modulates the frequency, rate or extent of salivary gland determination.	tmpzr1t_l9r_go_relaxed.owl	regulation of salivary gland determination													biological_process											owl:Class	
GO:0033531	biolink:NamedThing	stachyose metabolic process	The chemical reactions and pathways involving stachyose, the tetrasaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside.	tmpzr1t_l9r_go_relaxed.owl	stachyose metabolism													biological_process											owl:Class	
GO:0009311	biolink:NamedThing	oligosaccharide metabolic process	The chemical reactions and pathways involving oligosaccharides, molecules with between two and (about) 20 monosaccharide residues connected by glycosidic linkages.	tmpzr1t_l9r_go_relaxed.owl	multicellular organismal oligosaccharide metabolic process|oligosaccharide metabolism											GO:0051690		biological_process											owl:Class	
GO:0050368	biolink:NamedThing	tyrosine 2,3-aminomutase activity	Catalysis of the reaction: L-tyrosine = 3-amino-3-(4-hydroxyphenyl)propanoate.	tmpzr1t_l9r_go_relaxed.owl	tyrosine alpha,beta-mutase activity|L-tyrosine 2,3-aminomutase activity				MetaCyc:TYROSINE-23-AMINOMUTASE-RXN|RHEA:15781|EC:5.4.3.6|KEGG_REACTION:R00739									molecular_function											owl:Class	
GO:0016869	biolink:NamedThing	intramolecular transferase activity, transferring amino groups	Catalysis of the transfer of an amino group from one position to another within a single molecule.	tmpzr1t_l9r_go_relaxed.owl					EC:5.4.3.-									molecular_function											owl:Class	
GO:2001208	biolink:NamedThing	negative regulation of transcription elongation by RNA polymerase I	Any process that stops, prevents or reduces the frequency, rate or extent of transcription elongation mediated by RNA polymerase I.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of transcription elongation from RNA polymerase I promoter|negative regulation of RNA elongation from Pol I promoter							se	2011-11-11T10:46:36Z					biological_process											owl:Class	
GO:2001207	biolink:NamedThing	regulation of transcription elongation from RNA polymerase I promoter	Any process that modulates the frequency, rate or extent of transcription elongation from RNA polymerase I promoter.	tmpzr1t_l9r_go_relaxed.owl	regulation of RNA elongation from Pol I promoter							se	2011-11-11T10:46:28Z					biological_process											owl:Class	
GO:0006448	biolink:NamedThing	regulation of translational elongation	Any process that modulates the frequency, rate, extent or accuracy of translational elongation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0102184	biolink:NamedThing	cycloartenol 4alpha-methyl oxidase activity	Catalysis of the reaction: cycloartenol + NADH + O2 + H+ <=> 4alpha-hydroxymethyl,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-cholest-24-en-3beta-ol + NAD + H2O.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-11946									molecular_function											owl:Class	
GO:0035387	biolink:NamedThing	negative regulation of Roundabout signaling pathway	Any process that stops, prevents, or reduces the frequency, rate or extent of the Roundabout signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of Roundabout signalling pathway							bf	2010-03-18T02:40:00Z					biological_process											owl:Class	
GO:0036353	biolink:NamedThing	histone H2A-K119 monoubiquitination	The modification of histone H2A by addition of a single ubiquitin group to lysine-119 (H2A- K119) in metazoans, and at the equivalent residue in other organisms.	tmpzr1t_l9r_go_relaxed.owl	histone H2A monoubiquitination (H2A-K119)							bf	2012-09-19T11:52:25Z					biological_process											owl:Class	
GO:0035518	biolink:NamedThing	histone H2A monoubiquitination	The modification of histone H2A by addition of a single ubiquitin group.	tmpzr1t_l9r_go_relaxed.owl								bf	2010-05-04T04:22:09Z					biological_process											owl:Class	
GO:2000290	biolink:NamedThing	regulation of myotome development	Any process that modulates the frequency, rate or extent of myotome development.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-12-20T10:22:05Z					biological_process											owl:Class	
GO:0015172	biolink:NamedThing	acidic amino acid transmembrane transporter activity	Enables the transfer of acidic amino acids from one side of a membrane to the other. Acidic amino acids have side chains with a negative charge at pH 7.3.	tmpzr1t_l9r_go_relaxed.owl	acidic amino acid transporter activity				Reactome:R-HSA-372448									molecular_function											owl:Class	
GO:1905300	biolink:NamedThing	positive regulation of intestinal epithelial cell development	Any process that activates or increases the frequency, rate or extent of intestinal epithelial cell development.	tmpzr1t_l9r_go_relaxed.owl	activation of intestinal epithelial cell development|up-regulation of intestinal epithelial cell development|upregulation of intestinal epithelial cell development|up regulation of intestinal epithelial cell development							rph	2016-06-30T11:41:02Z					biological_process											owl:Class	
GO:1900106	biolink:NamedThing	positive regulation of hyaluranon cable assembly	Any process that activates or increases the frequency, rate or extent of hyaluranon cable assembly.	tmpzr1t_l9r_go_relaxed.owl	activation of hyaluranon cable assembly|up-regulation of HA cable assembly|activation of HA cable assembly|upregulation of hyaluranon cable assembly|upregulation of HA cable assembly|up regulation of hyaluranon cable assembly|positive regulation of HA cable assembly|up regulation of HA cable assembly|up-regulation of hyaluranon cable assembly							yaf	2012-02-16T01:00:54Z					biological_process											owl:Class	
GO:0044089	biolink:NamedThing	positive regulation of cellular component biogenesis	Any process that activates or increases the frequency, rate or extent of cellular component biogenesis, a process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cellular component.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0043458	biolink:NamedThing	ethanol biosynthetic process involved in glucose fermentation to ethanol	The chemical reactions and pathways resulting in the formation of ethanol, CH3-CH2-OH, as part of the process of glucose catabolism to ethanol, CO2 and ATP.	tmpzr1t_l9r_go_relaxed.owl	ethanol synthesis during fermentation|ethanol anabolism during fermentation|ethanol formation during fermentation													biological_process											owl:Class	
GO:0006115	biolink:NamedThing	ethanol biosynthetic process	The chemical reactions and pathways resulting in the formation of ethanol, CH3-CH2-OH, a colorless, water-miscible, flammable liquid produced by alcoholic fermentation.	tmpzr1t_l9r_go_relaxed.owl	ethanol biosynthesis|ethanol formation|ethanol anabolism|ethanol synthesis													biological_process											owl:Class	
GO:2000756	biolink:NamedThing	regulation of peptidyl-lysine acetylation	Any process that modulates the frequency, rate or extent of peptidyl-lysine acetylation.	tmpzr1t_l9r_go_relaxed.owl								yaf	2011-06-16T09:51:26Z					biological_process											owl:Class	
GO:0009663	biolink:NamedThing	plasmodesma organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a plasmodesma, a fine cytoplasmic channel, found in all higher plants, that connects the cytoplasm of one cell to that of an adjacent cell.	tmpzr1t_l9r_go_relaxed.owl	plasmodesma organization and biogenesis|plasmodesma organisation|plasmodesmata organization and biogenesis													biological_process											owl:Class	
GO:0045216	biolink:NamedThing	cell-cell junction organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cell-cell junction. A cell-cell junction is a specialized region of connection between two cells.	tmpzr1t_l9r_go_relaxed.owl	cell-cell junction organisation|cell-cell junction assembly and maintenance|cell-cell junction biogenesis|intercellular junction assembly and maintenance													biological_process											owl:Class	
GO:0006532	biolink:NamedThing	aspartate biosynthetic process	The chemical reactions and pathways resulting in the formation of aspartate, the anion derived from aspartic acid, 2-aminobutanedioic acid.	tmpzr1t_l9r_go_relaxed.owl	aspartate anabolism|aspartate biosynthesis|aspartate formation|aspartate synthesis													biological_process											owl:Class	
GO:0051712	biolink:NamedThing	positive regulation of killing of cells of other organism	Any process that activates or increases the frequency, rate or extent of the killing by an organism of cells in another organism.	tmpzr1t_l9r_go_relaxed.owl	upregulation of killing of cells of another organism|positive regulation by organism of programmed cell death in other organism involved in symbiotic interaction|up-regulation of killing of cells of another organism|positive regulation by organism of apoptotic process in other organism involved in symbiotic interaction|enhancement of other organism programmed cell death by organism|stimulation of killing of cells of another organism|induction by organism of apoptosis in other organism involved in symbiotic interaction|positive regulation by organism of non-apoptotic programmed cell death in other organism during symbiotic interaction|activation by organism of apoptotic programmed cell death in other organism during symbiotic interaction|induction by organism of apoptosis in other organism during symbiotic interaction|activation of killing of cells of another organism|up regulation of killing of cells of another organism	https://github.com/geneontology/go-ontology/issues/20287										GO:0052501|GO:0052388|GO:0052518|GO:0052330|GO:0052529		biological_process											owl:Class	
GO:0044598	biolink:NamedThing	doxorubicin metabolic process	The chemical reactions and pathways involving doxorubicin, an anthracycline antibiotic, used in cancer chemotherapy.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-05-01T03:30:21Z					biological_process											owl:Class	
GO:1902146	biolink:NamedThing	positive regulation of response to cell cycle checkpoint signaling	Any process that activates or increases the frequency, rate or extent of response to cell cycle checkpoint signaling.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of G1/S transition checkpoint effector process|up-regulation of response to signal involved in cell cycle checkpoint|positive regulation of response to signal involved in cell cycle checkpoint|up-regulation of response to signal involved in G2/M transition checkpoint|upregulation of cell cycle checkpoint effector process|activation of response to signal involved in G1/S transition checkpoint|positive regulation of cell cycle checkpoint effector process|up regulation of response to signal involved in G2/M transition checkpoint|up regulation of G2/M transition checkpoint effector process|up regulation of response to signal involved in cell cycle checkpoint|activation of cell cycle checkpoint effector process|positive regulation of G2/M transition checkpoint effector process|up-regulation of response to G2/M transition checkpoint signaling|up regulation of G1/S transition checkpoint effector process|activation of response to cell cycle checkpoint signaling|up regulation of response to signal involved in G1/S transition checkpoint|upregulation of response to signal involved in G2/M transition checkpoint|activation of response to signal involved in cell cycle checkpoint|upregulation of G1/S transition checkpoint effector process|up-regulation of response to cell cycle checkpoint signaling|activation of response to signal involved in G2/M transition checkpoint|upregulation of response to signal involved in G1/S transition checkpoint|activation of G1/S transition checkpoint effector process|up-regulation of response to signal involved in G1/S transition checkpoint|positive regulation of response to signal involved in G1/S transition checkpoint|positive regulation of response to G2/M transition checkpoint signaling|upregulation of G2/M transition checkpoint effector process|up regulation of response to cell cycle checkpoint signaling|positive regulation of response to signal involved in G2/M transition checkpoint|up-regulation of cell cycle checkpoint effector process|upregulation of response to cell cycle checkpoint signaling|up-regulation of G1/S transition checkpoint effector process|upregulation of response to G2/M transition checkpoint signaling|up-regulation of G2/M transition checkpoint effector process|activation of response to G1/S transition checkpoint signaling|up-regulation of response to G1/S transition checkpoint signaling|upregulation of response to signal involved in cell cycle checkpoint|activation of G2/M transition checkpoint effector process|positive regulation of response to G1/S transition checkpoint signaling|upregulation of response to G1/S transition checkpoint signaling|activation of response to G2/M transition checkpoint signaling|up regulation of response to G1/S transition checkpoint signaling|up regulation of cell cycle checkpoint effector process|up regulation of response to G2/M transition checkpoint signaling							jl	2013-05-21T15:43:45Z					biological_process											owl:Class	
GO:1902145	biolink:NamedThing	regulation of response to cell cycle checkpoint signaling	Any process that modulates the frequency, rate or extent of response to cell cycle checkpoint signaling.	tmpzr1t_l9r_go_relaxed.owl	regulation of response to signal involved in cell cycle checkpoint|regulation of response to signal involved in G2/M transition checkpoint|regulation of response to signal involved in G1/S transition checkpoint|regulation of response to G1/S transition checkpoint signaling|regulation of cell cycle checkpoint effector process|regulation of G1/S transition checkpoint effector process|regulation of response to G2/M transition checkpoint signaling|regulation of G2/M transition checkpoint effector process							jl	2013-05-21T15:43:40Z					biological_process											owl:Class	
GO:0120176	biolink:NamedThing	positive regulation of torso signaling pathway	Any process that activates or increases the frequency, rate or extent of the torso signaling pathway.	tmpzr1t_l9r_go_relaxed.owl								krc	2018-06-07T16:52:52Z					biological_process											owl:Class	
GO:0051599	biolink:NamedThing	response to hydrostatic pressure	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrostatic pressure stimulus. Hydrostatic pressure is the force acting on an object in a system where the fluid is at rest (as opposed to moving). The weight of the fluid above the object creates pressure on it.	tmpzr1t_l9r_go_relaxed.owl	response to biomechanical stress|response to static fluid pressure													biological_process											owl:Class	
GO:0009415	biolink:NamedThing	response to water	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of water.	tmpzr1t_l9r_go_relaxed.owl	response to water stimulus													biological_process											owl:Class	
GO:1903580	biolink:NamedThing	positive regulation of ATP metabolic process	Any process that activates or increases the frequency, rate or extent of ATP metabolic process.	tmpzr1t_l9r_go_relaxed.owl	up regulation of ATP metabolism|upregulation of ATP metabolism|up-regulation of ATP metabolism|activation of ATP metabolic process|up regulation of ATP metabolic process|upregulation of ATP metabolic process|up-regulation of ATP metabolic process|positive regulation of ATP metabolism|activation of ATP metabolism							sl	2014-10-30T19:04:42Z					biological_process											owl:Class	
GO:0097115	biolink:NamedThing	neurexin clustering involved in presynaptic membrane assembly	The receptor clustering process involved in assembly of the presynaptic membrane in which neurexins are localized to distinct domains in the cell membrane. Neurexins are synaptic cell surface proteins which act as cell recognition molecules at nerve terminals.	tmpzr1t_l9r_go_relaxed.owl	presynaptic neurexin clustering|Nrxn clustering|neurexin clustering							pr	2011-07-31T05:40:00Z					biological_process											owl:Class	
GO:0043113	biolink:NamedThing	receptor clustering	The receptor metabolic process that results in grouping of a set of receptors at a cellular location, often to amplify the sensitivity of a signaling response.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0042046	biolink:NamedThing	W-molybdopterin cofactor metabolic process	The chemical reactions and pathways involving the W-molybdopterin cofactor, essential for the catalytic activity of some enzymes. The cofactor consists of a mononuclear tungsten ion (W) coordinated by one or two molybdopterin ligands.	tmpzr1t_l9r_go_relaxed.owl	Moco metabolic process|Moco metabolism|W-molybdopterin cofactor metabolism													biological_process											owl:Class	
GO:0035966	biolink:NamedThing	response to topologically incorrect protein	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a protein that is not folded in its correct three-dimensional structure.	tmpzr1t_l9r_go_relaxed.owl	response to misfolded or unfolded protein							bf	2011-08-03T11:43:12Z					biological_process											owl:Class	
GO:0038190	biolink:NamedThing	VEGF-activated neuropilin signaling pathway	A series of molecular signals initiated by the binding of vascular endothelial growth factor (VEGF) to a neuropilin protein on the surface of a target cell, followed by transmission of the signal, and ending with regulation of a downstream cellular process, e.g. transcription.	tmpzr1t_l9r_go_relaxed.owl	vascular endothelial growth factor-activated neuropilin signaling pathway|VEGF-Npn-1 signaling							bf	2013-08-01T16:06:49Z					biological_process											owl:Class	
GO:0038189	biolink:NamedThing	neuropilin signaling pathway	A series of molecular signals initiated by the binding of an extracellular ligand to a neuropilin protein on the surface of a target cell, followed by transmission of the signal, and ending with regulation of a downstream cellular process, e.g. transcription.	tmpzr1t_l9r_go_relaxed.owl	Npn signaling							bf	2013-08-01T16:02:10Z					biological_process											owl:Class	
GO:2001069	biolink:NamedThing	glycogen binding	Binding to glycogen.	tmpzr1t_l9r_go_relaxed.owl	animal starch binding|liver starch binding							jl	2011-09-14T12:01:06Z					molecular_function											owl:Class	
GO:0003245	biolink:NamedThing	cardiac muscle tissue growth involved in heart morphogenesis	The developmental growth of cardiac muscle tissue that contributes to the shaping of the heart.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-10-13T11:44:21Z					biological_process											owl:Class	
GO:2001151	biolink:NamedThing	regulation of renal water transport	Any process that modulates the frequency, rate or extent of renal water transport.	tmpzr1t_l9r_go_relaxed.owl								yaf	2011-10-24T11:37:51Z					biological_process											owl:Class	
GO:1900132	biolink:NamedThing	positive regulation of lipid binding	Any process that activates or increases the frequency, rate or extent of lipid binding.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of lipid binding|activation of lipid binding|up regulation of lipid binding|upregulation of lipid binding							pm	2012-02-23T04:05:11Z					biological_process											owl:Class	
GO:1904131	biolink:NamedThing	negative regulation of convergent extension involved in neural plate elongation	Any process that stops, prevents or reduces the frequency, rate or extent of convergent extension involved in neural plate elongation.	tmpzr1t_l9r_go_relaxed.owl	inhibition of convergent extension involved in neural plate elongation|down regulation of convergent extension involved in neural plate elongation|downregulation of convergent extension involved in neural plate elongation|down-regulation of convergent extension involved in neural plate elongation							dph	2015-04-10T21:13:27Z					biological_process											owl:Class	
GO:1904104	biolink:NamedThing	negative regulation of convergent extension involved in gastrulation	Any process that stops, prevents or reduces the frequency, rate or extent of convergent extension involved in gastrulation.	tmpzr1t_l9r_go_relaxed.owl	inhibition of convergent extension involved in gastrulation|downregulation of convergent extension involved in gastrulation|down-regulation of convergent extension involved in gastrulation|down regulation of convergent extension involved in gastrulation							dph	2015-04-01T11:17:12Z					biological_process											owl:Class	
GO:0033809	biolink:NamedThing	anthocyanin 6''-O-malonyltransferase activity	Catalysis of the reaction: malonyl-CoA + an anthocyanidin 3-O-beta-D-glucoside = CoA + an anthocyanidin 3-O-(6-O-malonyl-beta-D-glucoside).	tmpzr1t_l9r_go_relaxed.owl	malonyl-coenzymeA:anthocyanidin-3-O-beta-D-glucoside 6''-O-malonyltransferase activity|malonyl-CoA:anthocyanidin-3-O-beta-D-glucoside 6''-O-malonyltransferase activity|Dv3MaT|3MaT				RHEA:16025|EC:2.3.1.171|MetaCyc:2.3.1.171-RXN									molecular_function											owl:Class	
GO:0043729	biolink:NamedThing	2-amino-5-formylamino-6-(5-phosphoribosylamino)pyrimidin-4(3H)-one formate-lyase activity	Catalysis of the reaction: 2-amino-5-formylamino-6-(5-phosphoribosylamino)pyrimidin-4(3H)-one + H2O = 2,5-diamino-6-(5-phosphoribosylamino)pyrimidin-4(3H)-one + formate.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0016829	biolink:NamedThing	lyase activity	Catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond. They differ from other enzymes in that two substrates are involved in one reaction direction, but only one in the other direction. When acting on the single substrate, a molecule is eliminated and this generates either a new double bond or a new ring.	tmpzr1t_l9r_go_relaxed.owl	other lyase activity				Reactome:R-HSA-6782895|Reactome:R-HSA-5696408|EC:4.-.-.-									molecular_function											owl:Class	
GO:0006048	biolink:NamedThing	UDP-N-acetylglucosamine biosynthetic process	The chemical reactions and pathways resulting in the formation of UDP-N-acetylglucosamine, a substance composed of N-acetylglucosamine, a common structural unit of oligosaccharides, in glycosidic linkage with uridine diphosphate.	tmpzr1t_l9r_go_relaxed.owl	UDP-N-acetylglucosamine anabolism|UDP-N-acetylglucosamine synthesis|UDP-GlcNAc biosynthetic process|UDP-N-acetylglucosamine formation|UDP-N-acetylglucosamine biosynthesis|UDP-GlcNAc biosynthesis				MetaCyc:UDPNAGSYN-PWY									biological_process											owl:Class	
GO:0050326	biolink:NamedThing	taxifolin 8-monooxygenase activity	Catalysis of the reaction: taxifolin + NAD(P)H + H+ + O2 = 2,3-dihydrogossypetin + NAD(P)+ + H2O.	tmpzr1t_l9r_go_relaxed.owl	taxifolin hydroxylase activity|taxifolin,NAD(P)H:oxygen oxidoreductase (8-hydroxylating)				MetaCyc:TAXIFOLIN-8-MONOOXYGENASE-RXN|EC:1.14.13.19									molecular_function											owl:Class	
GO:1901787	biolink:NamedThing	benzoyl-CoA metabolic process	The chemical reactions and pathways involving benzoyl-CoA.	tmpzr1t_l9r_go_relaxed.owl	benzoyl-CoA metabolism							yaf	2013-01-16T11:13:54Z					biological_process											owl:Class	
GO:0006746	biolink:NamedThing	FADH2 metabolic process	The chemical reactions and pathways involving the reduced form of flavin adenine dinucleotide.	tmpzr1t_l9r_go_relaxed.owl	reduced flavin adenine dinucleotide metabolic process|FADH2 metabolism													biological_process											owl:Class	
GO:0072387	biolink:NamedThing	flavin adenine dinucleotide metabolic process	The chemical reactions and pathways involving flavin adenine dinucleotide, which acts as a coenzyme or prosthetic group of various flavoprotein oxidoreductase enzymes.	tmpzr1t_l9r_go_relaxed.owl	flavin adenine dinucleotide metabolism|flavin-adenine dinucleotide metabolic process|FAD or FADH2 metabolic process							mah	2010-12-02T04:21:43Z					biological_process											owl:Class	
GO:0034468	biolink:NamedThing	glycosome lumen	The volume enclosed by the membrane of a glycosome.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0005782	biolink:NamedThing	peroxisomal matrix	The volume contained within the membranes of a peroxisome; in many cells the matrix contains a crystalloid core largely composed of urate oxidase.	tmpzr1t_l9r_go_relaxed.owl	peroxisomal lumen											GO:0031909		cellular_component											owl:Class	
GO:0047283	biolink:NamedThing	dolichyl-phosphate D-xylosyltransferase activity	Catalysis of the reaction: dolichol-phosphate + UDP-D-xylose = dolichyl D-xylosyl phosphate + UDP.	tmpzr1t_l9r_go_relaxed.owl	UDP-D-xylose:dolichyl-phosphate D-xylosyltransferase activity				MetaCyc:2.4.2.32-RXN|RHEA:15361|EC:2.4.2.32									molecular_function											owl:Class	
GO:0051589	biolink:NamedThing	negative regulation of neurotransmitter transport	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a neurotransmitter into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of neurotransmitter transport|down regulation of neurotransmitter transport|downregulation of neurotransmitter transport|inhibition of neurotransmitter transport													biological_process											owl:Class	
GO:0098893	biolink:NamedThing	extrinsic component of postsynaptic endocytic zone	The component of the postsynaptic endocytic zone membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:1903533	biolink:NamedThing	regulation of protein targeting	Any process that modulates the frequency, rate or extent of protein targeting.	tmpzr1t_l9r_go_relaxed.owl	regulation of nascent polypeptide association|regulation of protein sorting along secretory pathway							al	2014-10-08T14:49:03Z					biological_process											owl:Class	
GO:0001069	biolink:NamedThing	regulatory region RNA binding	Binding to a RNA region that regulates a nucleic acid-based process. Such processes include transcription, DNA replication, and DNA repair.	tmpzr1t_l9r_go_relaxed.owl								krc	2010-10-21T04:17:01Z					molecular_function											owl:Class	
GO:0001067	biolink:NamedThing	transcription regulatory region nucleic acid binding	Binding to a nucleic acid region that regulates a nucleic acid-based process. Such processes include transcription, DNA replication, and DNA repair.	tmpzr1t_l9r_go_relaxed.owl	regulatory region nucleic acid binding	https://github.com/geneontology/go-ontology/issues/20791						krc	2010-10-21T04:08:56Z					molecular_function											owl:Class	
GO:0047175	biolink:NamedThing	galactosylacylglycerol O-acyltransferase activity	Catalysis of the reaction: sn-3-D-galactosyl-sn-2-acylglycerol + acyl-[acyl-carrier protein] = D-galactosyldiacylglycerol + [acyl-carrier protein].	tmpzr1t_l9r_go_relaxed.owl	acyl-acyl-carrier protein: lysomonogalactosyldiacylglycerol acyltransferase activity|acyl-ACP:lyso-MGDG acyltransferase activity|acyl-acyl-carrier-protein:D-galactosylacylglycerol O-acyltransferase activity				EC:2.3.1.141|MetaCyc:2.3.1.141-RXN|RHEA:17057									molecular_function											owl:Class	
GO:1902414	biolink:NamedThing	protein localization to cell junction	A process in which a protein is transported to, or maintained in, a location within a cell junction.	tmpzr1t_l9r_go_relaxed.owl	protein localization in cell junction|protein localisation in cell junction|protein localisation to cell junction							tb	2013-09-13T16:55:57Z					biological_process											owl:Class	
GO:0090287	biolink:NamedThing	regulation of cellular response to growth factor stimulus	Any process that modulates the rate, frequency, or extent of a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth factor stimulus.	tmpzr1t_l9r_go_relaxed.owl								tb	2010-02-18T03:01:25Z					biological_process											owl:Class	
GO:0008732	biolink:NamedThing	L-allo-threonine aldolase activity	Catalysis of the reaction: L-allo-threonine = glycine + acetaldehyde.	tmpzr1t_l9r_go_relaxed.owl	LtaA|L-allo-threonine acetaldehyde-lyase activity				RHEA:26209|MetaCyc:LTAA-RXN|EC:4.1.2.49									molecular_function											owl:Class	
GO:0004793	biolink:NamedThing	threonine aldolase activity	Catalysis of the reaction: L-threonine = glycine + acetaldehyde.	tmpzr1t_l9r_go_relaxed.owl	L-threonine aldolase activity|L-threonine acetaldehyde-lyase (glycine-forming)|L-threonine acetaldehyde-lyase activity				RHEA:19625|MetaCyc:THREONINE-ALDOLASE-RXN|EC:4.1.2.5									molecular_function											owl:Class	
GO:1901031	biolink:NamedThing	regulation of response to reactive oxygen species	Any process that modulates the frequency, rate or extent of response to reactive oxygen species.	tmpzr1t_l9r_go_relaxed.owl	regulation of response to ROS|regulation of response to reactive oxidative species|regulation of response to ROI|regulation of response to active oxygen species|regulation of response to reactive oxygen intermediate|regulation of response to AOS							kmv	2012-06-20T07:47:06Z					biological_process											owl:Class	
GO:1902882	biolink:NamedThing	regulation of response to oxidative stress	Any process that modulates the frequency, rate or extent of response to oxidative stress.	tmpzr1t_l9r_go_relaxed.owl								kmv	2014-04-03T20:29:52Z					biological_process											owl:Class	
GO:0060763	biolink:NamedThing	mammary duct terminal end bud growth	The morphogenetic growth of the large, club-shaped terminal end of a mammary gland duct during prepubertal growth and during puberty.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-07-06T07:33:50Z					biological_process											owl:Class	
GO:0009740	biolink:NamedThing	gibberellic acid mediated signaling pathway	A series of molecular signals mediated by the detection of gibberellic acid.	tmpzr1t_l9r_go_relaxed.owl	gibberellic acid signaling|GA-signaling|gibberellic acid mediated signalling													biological_process											owl:Class	
GO:0010476	biolink:NamedThing	gibberellin mediated signaling pathway	The series of molecular signals generated as a consequence of gibberellin stimulus.	tmpzr1t_l9r_go_relaxed.owl	gibberellin-mediated signalling													biological_process											owl:Class	
GO:0002706	biolink:NamedThing	regulation of lymphocyte mediated immunity	Any process that modulates the frequency, rate, or extent of lymphocyte mediated immunity.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0031721	biolink:NamedThing	hemoglobin alpha binding	Binding to a hemoglobin alpha chain.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0030492	biolink:NamedThing	hemoglobin binding	Binding to hemoglobin, an oxygen carrying, conjugated protein containing four heme groups and globin.	tmpzr1t_l9r_go_relaxed.owl	globin binding|haemoglobin binding													molecular_function											owl:Class	
GO:1903478	biolink:NamedThing	actin filament bundle convergence involved in mitotic contractile ring assembly	Any actin filament bundle convergence that is involved in mitotic actomyosin contractile ring assembly.	tmpzr1t_l9r_go_relaxed.owl	actin filament bundle convergence involved in actomyosin contractile ring assembly involved in cytokinesis after mitosis|actin filament bundle convergence involved in mitotic actomyosin contractile ring assembly|actin filament bundle convergence involved in cytokinesis, actomyosin contractile ring assembly involved in mitotic cytokinesis|actin filament bundle convergence involved in contractile ring assembly involved in mitotic cytokinesis							vw	2014-09-23T15:03:11Z					biological_process											owl:Class	
GO:0005640	biolink:NamedThing	nuclear outer membrane	The outer, i.e. cytoplasm-facing, lipid bilayer of the nuclear envelope; continuous with the endoplasmic reticulum of the cell and sometimes studded with ribosomes.	tmpzr1t_l9r_go_relaxed.owl	perinuclear membrane|nucleus outer envelope				NIF_Subcellular:sao1617136075									cellular_component											owl:Class	
GO:0031968	biolink:NamedThing	organelle outer membrane	The outer, i.e. cytoplasm-facing in a cellular organelle, lipid bilayer of an organelle envelope.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0006231	biolink:NamedThing	dTMP biosynthetic process	The chemical reactions and pathways resulting in the formation of dTMP, deoxyribosylthymine monophosphate (2'-deoxyribosylthymine 5'-phosphate).	tmpzr1t_l9r_go_relaxed.owl	dTMP biosynthesis|dTMP formation|dTMP synthesis|dTMP anabolism													biological_process											owl:Class	
GO:0061390	biolink:NamedThing	positive regulation of direction of cell growth	Any process that increases the direction of cell growth.	tmpzr1t_l9r_go_relaxed.owl								dph	2011-07-14T10:22:55Z					biological_process											owl:Class	
GO:0009913	biolink:NamedThing	epidermal cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of an epidermal cell, any of the cells making up the epidermis.	tmpzr1t_l9r_go_relaxed.owl	hypodermal cell differentiation											GO:0043355		biological_process											owl:Class	
GO:0018227	biolink:NamedThing	peptidyl-S-12-hydroxyfarnesyl-L-cysteine biosynthetic process from peptidyl-cysteine	The modification of peptidyl-cysteine to form S-12-hydroxyfarnesyl-L-cysteine; formation of S-farnesycysteine may be coupled with subsequent cleavage of a carboxy-terminal tripeptide for the CXXX motif and methyl esterification of the farnesylated cysteine.	tmpzr1t_l9r_go_relaxed.owl	peptidyl-S-12-hydroxyfarnesyl-L-cysteine anabolism from peptidyl-cysteine|peptidyl-S-12-hydroxyfarnesyl-L-cysteine formation from peptidyl-cysteine|peptidyl-S-12-hydroxyfarnesyl-L-cysteine synthesis from peptidyl-cysteine				RESID:AA0103									biological_process											owl:Class	
GO:0032212	biolink:NamedThing	positive regulation of telomere maintenance via telomerase	Any process that activates or increases the frequency, rate or extent of the addition of telomeric repeats by telomerase.	tmpzr1t_l9r_go_relaxed.owl	up regulation of telomere maintenance via telomerase activity|activation of telomere maintenance via telomerase|stimulation of telomere maintenance via telomerase|up-regulation of telomere maintenance via telomerase activity|upregulation of telomere maintenance via telomerase activity													biological_process											owl:Class	
GO:0032210	biolink:NamedThing	regulation of telomere maintenance via telomerase	Any process that modulates the frequency, rate or extent of the addition of telomeric repeats by telomerase.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0035400	biolink:NamedThing	histone tyrosine kinase activity	Catalysis of the transfer of a phosphate group to a tyrosine residue of a histone. Histones are any of a group of water-soluble proteins found in association with the DNA of eukaroytic  chromosomes.	tmpzr1t_l9r_go_relaxed.owl	histone-tyrosine kinase activity							bf	2010-03-24T09:59:15Z					molecular_function											owl:Class	
GO:0004715	biolink:NamedThing	non-membrane spanning protein tyrosine kinase activity	Catalysis of the reaction: ATP + protein L-tyrosine = ADP + protein L-tyrosine phosphate by a non-membrane spanning protein.	tmpzr1t_l9r_go_relaxed.owl	non-specific protein-tyrosine kinase activity|cytoplasmic protein tyrosine kinase activity|ATP:protein-L-tyrosine O-phosphotransferase (non-specific) activity|focal adhesion kinase activity|ATP:protein-tyrosine O-phosphotransferase activity|janus kinase 1 activity|janus kinase 2 activity|Bruton's tyrosine kinase activity|p60c-src protein tyrosine kinase activity|janus kinase 3 activity				Reactome:R-HSA-1168767|Reactome:R-HSA-1369115|Reactome:R-HSA-879910|Reactome:R-HSA-437936|Reactome:R-HSA-6786096|Reactome:R-HSA-1112703|Reactome:R-HSA-1168423|Reactome:R-HSA-6788582|Reactome:R-HSA-1295519|MetaCyc:2.7.10.2-RXN|Reactome:R-HSA-6786095|Reactome:R-HSA-453200|Reactome:R-HSA-1112602|Reactome:R-HSA-432148|EC:2.7.10.2|Reactome:R-HSA-8871373|Reactome:R-HSA-1168459									molecular_function											owl:Class	
GO:0044733	biolink:NamedThing	envenomation resulting in modulation of acid-sensing ion channel activity in other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with a resultant change in the activity of an acid-sensing ion channel (ASIC) in the bitten organism.	tmpzr1t_l9r_go_relaxed.owl	envenomation resulting in modulation of ASIC channel activity in other organism							jl	2012-11-06T15:58:36Z					biological_process											owl:Class	
GO:0044560	biolink:NamedThing	envenomation resulting in modulation of ion channel activity in other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with a resultant change in the activity of an ion channel in the bitten organism.	tmpzr1t_l9r_go_relaxed.owl	envenomation resulting in regulation of ion channel activity in other organism							jl	2012-04-05T03:46:35Z					biological_process											owl:Class	
GO:0042766	biolink:NamedThing	nucleosome mobilization	The movement of nucleosomes along a DNA fragment.	tmpzr1t_l9r_go_relaxed.owl	nucleosome sliding													biological_process											owl:Class	
GO:0034728	biolink:NamedThing	nucleosome organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of one or more nucleosomes.	tmpzr1t_l9r_go_relaxed.owl	nucleosome organisation													biological_process											owl:Class	
GO:1904926	biolink:NamedThing	response to palmitoleic acid	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a palmitoleic acid stimulus.	tmpzr1t_l9r_go_relaxed.owl								mr	2016-01-27T23:07:22Z					biological_process											owl:Class	
GO:2000487	biolink:NamedThing	positive regulation of glutamine transport	Any process that activates or increases the frequency, rate or extent of glutamine transport.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of L-glutamine transport							bf	2011-03-11T09:33:39Z					biological_process											owl:Class	
GO:1903793	biolink:NamedThing	positive regulation of anion transport	Any process that activates or increases the frequency, rate or extent of anion transport.	tmpzr1t_l9r_go_relaxed.owl	activation of anion transport|up-regulation of anion transport|upregulation of anion transport|up regulation of anion transport							sl	2015-01-12T21:50:30Z					biological_process											owl:Class	
GO:0003346	biolink:NamedThing	epicardium-derived cell migration to the myocardium	The orderly movement of a cell that have undergone an epithelial to mesenchymal transition from the epicardium into the myocardium.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-12-01T11:00:42Z					biological_process											owl:Class	
GO:0048335	biolink:NamedThing	negative regulation of mesodermal cell fate determination	Any process that stops, prevents, or reduces the frequency, rate or extent of mesoderm cell fate determination.	tmpzr1t_l9r_go_relaxed.owl	inhibition of mesodermal cell fate determination|down-regulation of mesodermal cell fate determination|downregulation of mesodermal cell fate determination|down regulation of mesodermal cell fate determination													biological_process											owl:Class	
GO:0048334	biolink:NamedThing	regulation of mesodermal cell fate determination	Any process that modulates the frequency, rate or extent of mesoderm cell fate determination.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0110027	biolink:NamedThing	negative regulation of DNA strand resection involved in replication fork processing	Any process that stops, prevents, or reduces the frequency, rate or extent of DNA strand resection involved in replication fork processing.	tmpzr1t_l9r_go_relaxed.owl								kmv	2017-07-05T18:39:49Z					biological_process											owl:Class	
GO:0002794	biolink:NamedThing	regulation of antimicrobial peptide secretion	Any process that modulates the frequency, rate, or extent of antimicrobial peptide secretion.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0006851	biolink:NamedThing	mitochondrial calcium ion transmembrane transport	The process in which a calcium ion (Ca2+) is transported across a mitochondrial membrane, into or out of the mitochondrion.	tmpzr1t_l9r_go_relaxed.owl	mitochondrial calcium transport													biological_process											owl:Class	
GO:0070759	biolink:NamedThing	negative regulation of interleukin-35-mediated signaling pathway	Any process that decreases the rate, frequency or extent of the series of molecular events generated as a consequence of interleukin-35 binding to a cell surface receptor.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of interleukin-35-mediated signalling pathway|negative regulation of IL-35-mediated signaling pathway							mah	2009-06-23T02:02:07Z					biological_process											owl:Class	
GO:1903917	biolink:NamedThing	positive regulation of endoplasmic reticulum stress-induced eIF2 alpha dephosphorylation	Any process that activates or increases the frequency, rate or extent of endoplasmic reticulum stress-induced eIF2alpha dephosphorylation.	tmpzr1t_l9r_go_relaxed.owl	activation of eIF2alpha dephosphorylation in response to endoplasmic reticulum stress|up-regulation of regulation of translation initiation by eIF2alpha dephosphorylation in response to endoplasmic reticulum stress|upregulation of regulation of translation initiation by eIF2alpha dephosphorylation in response to endoplasmic reticulum stress|positive regulation of eIF2alpha dephosphorylation in response to ER stress|positive regulation of eIF2alpha dephosphorylation in response to endoplasmic reticulum stress|upregulation of eIF2alpha dephosphorylation in response to ER stress|positive regulation of regulation of translation initiation by eIF2alpha dephosphorylation in response to endoplasmic reticulum stress|activation of eIF2alpha dephosphorylation in response to ER stress|up regulation of eIF2alpha dephosphorylation in response to endoplasmic reticulum stress|upregulation of eIF2alpha dephosphorylation in response to endoplasmic reticulum stress|activation of regulation of translation initiation by eIF2alpha dephosphorylation in response to endoplasmic reticulum stress|up regulation of regulation of translation initiation by eIF2alpha dephosphorylation in response to endoplasmic reticulum stress|up regulation of eIF2alpha dephosphorylation in response to ER stress|positive regulation of ER stress-induced eIF2 alpha dephosphorylation|up-regulation of eIF2alpha dephosphorylation in response to ER stress|up-regulation of eIF2alpha dephosphorylation in response to endoplasmic reticulum stress							bf	2015-02-09T11:18:24Z					biological_process											owl:Class	
GO:1903916	biolink:NamedThing	regulation of endoplasmic reticulum stress-induced eIF2 alpha dephosphorylation	Any process that modulates the frequency, rate or extent of endoplasmic reticulum stress-induced eIF2alpha dephosphorylation.	tmpzr1t_l9r_go_relaxed.owl	regulation of ER stress-induced eIF2 alpha dephosphorylation|regulation of eIF2alpha dephosphorylation in response to ER stress|regulation of regulation of translation initiation by eIF2alpha dephosphorylation in response to endoplasmic reticulum stress|regulation of eIF2alpha dephosphorylation in response to endoplasmic reticulum stress							bf	2015-02-09T11:18:14Z					biological_process											owl:Class	
GO:0075250	biolink:NamedThing	negative regulation of aeciospore formation	Any process that stops, prevents, or reduces the frequency, rate or extent of aeciospore formation, a process in which a dikaryotic spore of typically a rust fungus is produced in an aecium.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0019156	biolink:NamedThing	isoamylase activity	Catalysis of the hydrolysis of alpha-(1,6)-D-glucosidic branch linkages in glycogen, amylopectin and their beta-limits dextrins.	tmpzr1t_l9r_go_relaxed.owl	debranching enzyme activity|glycogen alpha-1,6-glucanohydrolase activity				MetaCyc:3.2.1.68-RXN|MetaCyc:RXN-12280|EC:3.2.1.68|MetaCyc:RXN-14380									molecular_function											owl:Class	
GO:0004133	biolink:NamedThing	glycogen debranching enzyme activity	Catalysis of the cleavage of branch points in branched glycogen polymers.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0060735	biolink:NamedThing	regulation of eIF2 alpha phosphorylation by dsRNA	Any process that modulates the rate, frequency, or extent of eIF2 alpha phosphorylation as a cellular response to double-stranded RNA.	tmpzr1t_l9r_go_relaxed.owl	regulation of eIF2 alpha phosphorylation by PKR|regulation of eIF2 alpha phosphorylation by double-stranded RNA							dph	2009-06-12T02:27:14Z					biological_process											owl:Class	
GO:0048673	biolink:NamedThing	collateral sprouting of intact axon in response to injury	The process in which outgrowths develop from the axons of intact undamaged neurons as a result of injury to an axon. The collateral sprouts typically appear from undamaged axons in a tissue which has had part of its nerve supply removed, and they can often innervate successfully any cells that have lost some or all of their original synaptic input.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0031103	biolink:NamedThing	axon regeneration	The regrowth of axons following their loss or damage.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0032174	biolink:NamedThing	cellular bud neck septin collar	A tubular structure with flared ends, shaped like an hourglass and composed of highly ordered arrays of septin filaments, that forms at the bud neck of a dividing cell. In S. cerevisiae, this structure is located at the bud neck throughout most of the cell cycle and the septins are fixed within the structure, not exchanging with soluble septins. This septin structure acts as a scaffold for other proteins that function at the bud neck.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0000399	biolink:NamedThing	cellular bud neck septin structure	Any of a series of septin structures that are localized in the bud neck of a budding fungal cell during the cell cycle.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0045887	biolink:NamedThing	positive regulation of synaptic assembly at neuromuscular junction	Any process that activates or increases the frequency, rate or extent of synaptic assembly at neuromuscular junction.	tmpzr1t_l9r_go_relaxed.owl	activation of synaptic growth at neuromuscular junction|stimulation of synaptic growth at neuromuscular junction|upregulation of synaptic growth at neuromuscular junction|up regulation of synaptic growth at neuromuscular junction|positive regulation of synaptic growth at neuromuscular junction|up-regulation of synaptic growth at neuromuscular junction													biological_process											owl:Class	
GO:0009154	biolink:NamedThing	purine ribonucleotide catabolic process	The chemical reactions and pathways resulting in the breakdown of a purine ribonucleotide, a compound consisting of ribonucleoside (a purine base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.	tmpzr1t_l9r_go_relaxed.owl	purine ribonucleotide catabolism|purine ribonucleotide degradation|purine ribonucleotide breakdown													biological_process											owl:Class	
GO:0071325	biolink:NamedThing	cellular response to mannitol stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mannitol stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-12-10T05:27:00Z					biological_process											owl:Class	
GO:0061134	biolink:NamedThing	peptidase regulator activity	Binds to and modulates the activity of a peptidase, any enzyme that catalyzes the hydrolysis peptide bonds.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-05-17T01:15:24Z					molecular_function											owl:Class	
GO:0120049	biolink:NamedThing	snRNA (adenine-N6)-methylation	The posttranscriptional N6-methylation of an adenine residue in an snRNA molecule.	tmpzr1t_l9r_go_relaxed.owl								krc	2017-06-02T20:56:51Z					biological_process											owl:Class	
GO:0040031	biolink:NamedThing	snRNA modification	The covalent alteration of one or more nucleotides within snRNA, resulting in a change in the properties of the snRNA.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1905597	biolink:NamedThing	positive regulation of low-density lipoprotein particle receptor binding	Any process that activates or increases the frequency, rate or extent of low-density lipoprotein particle receptor binding.	tmpzr1t_l9r_go_relaxed.owl	activation of low-density lipoprotein receptor binding|up-regulation of LDL receptor binding|up-regulation of low-density lipoprotein receptor binding|activation of low-density lipoprotein particle receptor binding|up-regulation of low-density lipoprotein particle receptor binding|up regulation of low-density lipoprotein particle receptor binding|upregulation of LDL receptor binding|positive regulation of LDL receptor binding|positive regulation of low-density lipoprotein receptor binding|activation of LDL receptor binding|upregulation of low-density lipoprotein particle receptor binding|up regulation of low-density lipoprotein receptor binding|up regulation of LDL receptor binding|upregulation of low-density lipoprotein receptor binding							nc	2016-10-26T10:57:40Z					biological_process											owl:Class	
GO:1900122	biolink:NamedThing	positive regulation of receptor binding	Any process that activates or increases the frequency, rate or extent of a protein or other molecule binding to a receptor.	tmpzr1t_l9r_go_relaxed.owl	activation of receptor binding|up regulation of receptor binding|upregulation of receptor binding							bf	2012-02-22T11:41:00Z					biological_process											owl:Class	
GO:0070059	biolink:NamedThing	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress	A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced in response to a stimulus indicating endoplasmic reticulum (ER) stress, and ends when the execution phase of apoptosis is triggered. ER stress usually results from the accumulation of unfolded or misfolded proteins in the ER lumen.	tmpzr1t_l9r_go_relaxed.owl	apoptosis in response to endoplasmic reticulum stress|apoptosis triggered by ER stress|intrinsic apoptotic signaling pathway induced by endoplasmic reticulum stress|endoplasmic reticulum stress-induced apoptosis|apoptosis in response to ER stress|ER stress-induced apoptosis													biological_process											owl:Class	
GO:0102816	biolink:NamedThing	UDP-D-glucose:delphinidin 3-O-glucosyl-5-O-caffeoylglucoside -O-beta-D-glucosyltransferase activity	Catalysis of the reaction: UDP-alpha-D-glucose + delphinidin 3-O-glucosyl-5-O-caffeoylglucoside <=> H+ + delphinidin 3-O-glucosyl-5-O-(caffeoylglucoside-3'-O-glucoside) + UDP.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-8234|EC:2.4.1.298|RHEA:35423									molecular_function											owl:Class	
GO:0030838	biolink:NamedThing	positive regulation of actin filament polymerization	Any process that activates or increases the frequency, rate or extent of actin polymerization.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of actin polymerization|stimulation of actin filament polymerization|up regulation of actin filament polymerization|positive regulation of actin polymerization and/or depolymerization|up-regulation of actin filament polymerization|activation of actin filament polymerization|upregulation of actin filament polymerization					Note that this term was split from 'positive regulation of actin polymerization and/or depolymerization ; GO:0045758' (sibling term 'positive regulation of actin depolymerization ; GO:0030836').								biological_process											owl:Class	
GO:0051495	biolink:NamedThing	positive regulation of cytoskeleton organization	Any process that activates or increases the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures.	tmpzr1t_l9r_go_relaxed.owl	up regulation of cytoskeleton organization|positive regulation of cytoskeleton organization and biogenesis|stimulation of cytoskeleton organization|up-regulation of cytoskeleton organization|positive regulation of cytoskeleton organisation|upregulation of cytoskeleton organization|activation of cytoskeleton organization													biological_process											owl:Class	
GO:0031036	biolink:NamedThing	myosin II filament assembly	The formation of a bipolar filament composed of myosin II molecules.	tmpzr1t_l9r_go_relaxed.owl	myosin II polymerization													biological_process											owl:Class	
GO:0031034	biolink:NamedThing	myosin filament assembly	The aggregation, arrangement and bonding together of a filament composed of myosin molecules.	tmpzr1t_l9r_go_relaxed.owl	myosin polymerization													biological_process											owl:Class	
GO:0051551	biolink:NamedThing	aurone biosynthetic process	The chemical reactions and pathways resulting in the formation of aurones, a series of yellow plant pigments.	tmpzr1t_l9r_go_relaxed.owl	benzalcoumaran-3-one biosynthetic process|benzalcoumaran-3-one biosynthesis													biological_process											owl:Class	
GO:0031747	biolink:NamedThing	type 2 cysteinyl leukotriene receptor binding	Binding to a type 2 cysteinyl leukotriene receptor.	tmpzr1t_l9r_go_relaxed.owl	type 2 cysteinyl leukotriene receptor ligand													molecular_function											owl:Class	
GO:0009835	biolink:NamedThing	fruit ripening	An aging process that has as participant a fruit. Ripening causes changes in one or more characteristics of a fruit (color, aroma, flavor, texture, hardness, cell wall structure) and may make it more attractive to animals and aid in seed dispersal.	tmpzr1t_l9r_go_relaxed.owl	fruit maturation|fruit senescence				Wikipedia:Ripening									biological_process											owl:Class	
GO:0051978	biolink:NamedThing	lysophospholipid:sodium symporter activity	Enables the directed movement of lysophospholipids from one side of a membrane to the other. A lysophospholipid is a phospholipid that lacks one of its fatty acyl chains; it is an intermediate formed during digestion of dietary and biliary phospholipids.	tmpzr1t_l9r_go_relaxed.owl	lysophospholipid transporter activity	https://github.com/geneontology/go-ontology/issues/17207												molecular_function											owl:Class	
GO:0070299	biolink:NamedThing	positive regulation of phosphorelay signal transduction system	Any process that activates or increases the frequency, rate or extent of signal transduction via a phosphorelay signal transduction system.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of histidyl-aspartyl phosphorelay|stimulation of two-component signal transduction|up regulation of two-component signal transduction|activation of two-component signal transduction|positive regulation of two-component signal transduction system (phosphorelay)|upregulation of two-component signal transduction|up-regulation of two-component signal transduction													biological_process											owl:Class	
GO:0042903	biolink:NamedThing	tubulin deacetylase activity	Catalysis of the reaction: N-acetyl(alpha-tubulin) + H2O = alpha-tubulin + acetate.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-5618331									molecular_function											owl:Class	
GO:0033558	biolink:NamedThing	protein deacetylase activity	Catalysis of the hydrolysis of an acetyl group or groups from a protein substrate.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-9626962|Reactome:R-HSA-8952069|Reactome:R-HSA-5693092									molecular_function											owl:Class	
GO:1902114	biolink:NamedThing	D-valine metabolic process	The chemical reactions and pathways involving D-valine.	tmpzr1t_l9r_go_relaxed.owl	D-valine metabolism							al	2013-05-13T23:27:23Z					biological_process											owl:Class	
GO:0006573	biolink:NamedThing	valine metabolic process	The chemical reactions and pathways involving valine, 2-amino-3-methylbutanoic acid.	tmpzr1t_l9r_go_relaxed.owl	valine metabolism													biological_process											owl:Class	
GO:0045779	biolink:NamedThing	negative regulation of bone resorption	Any process that stops, prevents, or reduces the frequency, rate or extent of bone resorption.	tmpzr1t_l9r_go_relaxed.owl	downregulation of bone resorption|down-regulation of bone resorption|down regulation of bone resorption|inhibition of bone resorption													biological_process											owl:Class	
GO:0033186	biolink:NamedThing	CAF-1 complex	A conserved heterotrimeric protein complex that promotes histone H3 and H4 deposition onto newly synthesized DNA during replication or DNA repair; specifically facilitates replication-dependent nucleosome assembly with the major histone H3 (H3.1). In many species the CAF-1 subunits are designated p150, p60, and p48.	tmpzr1t_l9r_go_relaxed.owl	chromatin assembly factor 1 complex					In yeast the subunits are MSI1/p50, CAC2/p60 and CAC1/p90.								cellular_component											owl:Class	
GO:1990064	biolink:NamedThing	ground tissue pattern formation	The regionalization process that gives rise to the patterning of the ground tissue.	tmpzr1t_l9r_go_relaxed.owl	ground tissue patterning							tb	2013-03-21T23:24:44Z					biological_process											owl:Class	
GO:0044806	biolink:NamedThing	G-quadruplex DNA unwinding	The process by which G-quadruplex (also known as G4) DNA, which is a four-stranded DNA structure held together by guanine base pairing, is unwound or 'melted'.	tmpzr1t_l9r_go_relaxed.owl								jl	2013-09-10T16:16:16Z					biological_process											owl:Class	
GO:0031434	biolink:NamedThing	mitogen-activated protein kinase kinase binding	Binding to a mitogen-activated protein kinase kinase, a protein that can phosphorylate a MAP kinase.	tmpzr1t_l9r_go_relaxed.owl	MAPKK binding													molecular_function											owl:Class	
GO:0019901	biolink:NamedThing	protein kinase binding	Binding to a protein kinase, any enzyme that catalyzes the transfer of a phosphate group, usually from ATP, to a protein substrate.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0033491	biolink:NamedThing	coniferin metabolic process	The chemical reactions and pathways involving coniferin, 4-(3-hydroxyprop-1-en-1-yl)-2-methoxyphenyl beta-D-glucopyranoside.	tmpzr1t_l9r_go_relaxed.owl	coniferin metabolism				MetaCyc:PWY-116									biological_process											owl:Class	
GO:0004305	biolink:NamedThing	ethanolamine kinase activity	Catalysis of the reaction: ATP + ethanolamine = ADP + 2 H(+) + phosphoethanolamine.	tmpzr1t_l9r_go_relaxed.owl	ethanolamine kinase (phosphorylating)|ATP:ethanolamine O-phosphotransferase activity|ethanolamine phosphokinase activity				MetaCyc:ETHANOLAMINE-KINASE-RXN|EC:2.7.1.82|KEGG_REACTION:R01468|RHEA:13069|Reactome:R-HSA-1483222									molecular_function											owl:Class	
GO:0070754	biolink:NamedThing	regulation of interleukin-35 production	Any process that modulates the frequency, rate, or extent of interleukin-35 production.	tmpzr1t_l9r_go_relaxed.owl	regulation of interleukin-35 biosynthetic process|regulation of IL-35 production							mah	2009-06-23T01:29:17Z			GO:0070750		biological_process											owl:Class	
GO:0047721	biolink:NamedThing	indoleacetate-lysine synthetase activity	Catalysis of the reaction: (indol-3-yl)acetate + L-lysine + ATP = N(6)-[(indole-3-yl)acetyl]-L-lysine + ADP + 2 H(+) + phosphate.	tmpzr1t_l9r_go_relaxed.owl	N-(indole-3-acetyl)-L-lysine synthetase activity|(indol-3-yl)acetate:L-lysine ligase (ADP-forming)|IAA-lysine synthetase activity|indoleacetate:L-lysine ligase (ADP-forming)|indoleacetate-lysine ligase activity				RHEA:14857|EC:6.3.2.20|MetaCyc:INDOLEACETATE--LYSINE-LIGASE-RXN|KEGG_REACTION:R03095									molecular_function											owl:Class	
GO:0010279	biolink:NamedThing	indole-3-acetic acid amido synthetase activity	Catalysis of the reaction: indole-3-acetic acid + an amino acid = an indole-3-acetic acid amide conjugate.	tmpzr1t_l9r_go_relaxed.owl	IAA amido synthetase activity|IAA amino acid synthetase activity|IAA amino acid conjugate synthetase activity													molecular_function											owl:Class	
GO:2000395	biolink:NamedThing	regulation of ubiquitin-dependent endocytosis	Any process that modulates the frequency, rate or extent of ubiquitin-dependent endocytosis.	tmpzr1t_l9r_go_relaxed.owl	regulation of ubiquitin-mediated endocytosis							mah	2011-02-22T11:24:52Z					biological_process											owl:Class	
GO:0016169	biolink:NamedThing	bacteriochlorophyll c binding	Binding to bacteriochlorophyll c, a chlorophyll of photosynthetic bacteria, for example green sulfur bacteria.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0042314	biolink:NamedThing	bacteriochlorophyll binding	Binding to bacteriochlorophyll, a form of chlorophyll found in photosynthetic bacteria, such as the purple and green bacteria. There are several types, designated a to g. Bacteriochlorophyll a and bacteriochlorophyll b are structurally similar to the chlorophyll a and chlorophyll b found in plants.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0009212	biolink:NamedThing	pyrimidine deoxyribonucleoside triphosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of pyrimidine deoxyribonucleoside triphosphate, a compound consisting of a pyrimidine base linked to a deoxyribose sugar esterified with triphosphate on the sugar.	tmpzr1t_l9r_go_relaxed.owl	pyrimidine deoxyribonucleoside triphosphate synthesis|pyrimidine deoxyribonucleoside triphosphate biosynthesis|pyrimidine deoxyribonucleoside triphosphate anabolism|pyrimidine deoxyribonucleoside triphosphate formation													biological_process											owl:Class	
GO:0051950	biolink:NamedThing	positive regulation of gamma-aminobutyric acid uptake involved in transmission of nerve impulse	Any process that activates, maintains or increases the frequency, rate or extent of the directed movement of gamma-aminobutyric acid (GABA, 4-aminobutyrate) into a neuron or glial cell.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of gamma-aminobutyric acid reuptake|up-regulation of gamma-aminobutyric acid uptake during transmission of nerve impulse|up regulation of gamma-aminobutyric acid uptake during transmission of nerve impulse|positive regulation of gamma-aminobutyric acid uptake involved in conduction of nerve impulse|positive regulation of GABA uptake during transmission of nerve impulse|positive regulation of 4-aminobutyrate uptake during transmission of nerve impulse|positive regulation of 4-aminobutyrate reuptake|activation of gamma-aminobutyric acid uptake during transmission of nerve impulse|positive regulation of GABA reuptake|upregulation of gamma-aminobutyric acid uptake during transmission of nerve impulse|stimulation of gamma-aminobutyric acid uptake during transmission of nerve impulse|positive regulation of gamma-aminobutyric acid uptake during transmission of nerve impulse													biological_process											owl:Class	
GO:0051943	biolink:NamedThing	positive regulation of amino acid uptake involved in synaptic transmission	Any process that activates, maintains or increases the frequency, rate or extent of the directed movement of amino acid neurotransmitters into a neuron or glial cell.	tmpzr1t_l9r_go_relaxed.owl	stimulation of amino acid uptake during transmission of nerve impulse|up regulation of amino acid uptake during transmission of nerve impulse|upregulation of amino acid uptake during transmission of nerve impulse|up-regulation of amino acid uptake during transmission of nerve impulse|activation of amino acid uptake during transmission of nerve impulse|positive regulation of amino acid neurotransmitter uptake|positive regulation of amino acid neurotransmitter reuptake													biological_process											owl:Class	
GO:0070296	biolink:NamedThing	sarcoplasmic reticulum calcium ion transport	The directed movement of calcium ions (Ca2+) into, out of or within the sarcoplasmic reticulum.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0006816	biolink:NamedThing	calcium ion transport	The directed movement of calcium (Ca) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	mitochondrial sodium/calcium ion exchange|calcium transport|sodium:calcium exchange													biological_process											owl:Class	
GO:0051835	biolink:NamedThing	positive regulation of synapse structural plasticity	Any process that activates, maintains or increases the frequency, rate or extent of synaptic structural plasticity.	tmpzr1t_l9r_go_relaxed.owl	up regulation of synapse structural plasticity|activation of synapse structural plasticity|upregulation of synapse structural plasticity|up-regulation of synapse structural plasticity|stimulation of synapse structural plasticity													biological_process											owl:Class	
GO:0060268	biolink:NamedThing	negative regulation of respiratory burst	Any process that decreases the rate frequency or extent of a phase of elevated metabolic activity, during which oxygen consumption increases; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0140515	biolink:NamedThing	mitotic nuclear bridge organization	A mitotic cell cycle process which results in the assembly, arrangement, or disassembly of the mitotic nuclear bridge during closed mitosis.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/19948						pg	2020-09-09T14:04:33Z					biological_process											owl:Class	
GO:0101024	biolink:NamedThing	mitotic nuclear membrane organization	A mitotic cell cycle process which results in the assembly, arrangement, or disassembly of the nuclear inner or outer membrane during mitosis.	tmpzr1t_l9r_go_relaxed.owl	nuclear membrane organization involved in mitotic nuclear division	https://github.com/geneontology/go-ontology/issues/19949				This process only occurs in organisms which undergo 'closed mitosis' without nuclear breakdown.								biological_process											owl:Class	
GO:1905868	biolink:NamedThing	regulation of 3'-UTR-mediated mRNA stabilization	Any process that modulates the frequency, rate or extent of 3'-UTR-mediated mRNA stabilization.	tmpzr1t_l9r_go_relaxed.owl	regulation of 3'-untranslated region-mediated mRNA stabilization							rz	2017-01-27T11:51:37Z					biological_process											owl:Class	
GO:0044632	biolink:NamedThing	negative regulation of complement activation, lectin pathway in other organism	Any process that stops, prevents, or reduces the rate of complement activation by the lectin pathway, in a different organism.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-07-05T01:18:43Z					biological_process											owl:Class	
GO:0001869	biolink:NamedThing	negative regulation of complement activation, lectin pathway	Any process that stops, prevents, or reduces the rate of complement activation by the lectin pathway.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of complement activation, lectin pathway|inhibition of complement activation, lectin pathway|down regulation of complement activation, lectin pathway|downregulation of complement activation, lectin pathway|negative regulation of complement cascade, lectin pathway													biological_process											owl:Class	
GO:0031578	biolink:NamedThing	mitotic spindle orientation checkpoint signaling	A signaling process that monitors and signals errors in the placement or orientation of the spindle in the cell. This delays the completion of anaphase until errors are corrected.	tmpzr1t_l9r_go_relaxed.owl	SOC|mitotic spindle orientation checkpoint|signal transduction involved in mitotic cell cycle spindle orientation checkpoint|SPOC|mitotic cell cycle spindle orientation checkpoint|spindle position checkpoint	https://github.com/geneontology/go-ontology/issues/20935										GO:0072483		biological_process											owl:Class	
GO:0043570	biolink:NamedThing	maintenance of DNA repeat elements	Any process involved in sustaining the fidelity and copy number of DNA repeat elements.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0051049	biolink:NamedThing	regulation of transport	Any process that modulates the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0045899	biolink:NamedThing	positive regulation of RNA polymerase II transcription preinitiation complex assembly	Any process that activates or increases the frequency, rate or extent of RNA polymerase II transcriptional preinitiation complex assembly.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of RNA polymerase II transcriptional preinitiation complex assembly|positive regulation of RNA polymerase II transcriptional pre-initiation complex assembly|up-regulation of RNA polymerase II transcriptional preinitiation complex assembly|up regulation of RNA polymerase II transcriptional preinitiation complex assembly|positive regulation of RNA polymerase II transcriptional preinitiation complex formation|positive regulation of RNA polymerase II transcriptional pre-initiation complex biosynthesis|stimulation of RNA polymerase II transcriptional preinitiation complex assembly|activation of RNA polymerase II transcriptional preinitiation complex assembly|upregulation of RNA polymerase II transcriptional preinitiation complex assembly													biological_process											owl:Class	
GO:0060261	biolink:NamedThing	positive regulation of transcription initiation from RNA polymerase II promoter	Any process that increases the rate, frequency or extent of a process involved in starting transcription from an RNA polymerase II promoter.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:2000960	biolink:NamedThing	regulation of cellooligosaccharide metabolic process	Any process that modulates the frequency, rate or extent of cellooligosaccharide metabolic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of cellooligosaccharide metabolism							tt	2011-08-01T02:25:54Z					biological_process											owl:Class	
GO:0018288	biolink:NamedThing	iron incorporation into iron-sulfur cluster via tetrakis-L-cysteinyl tetrairon tetrasulfide	The incorporation of iron into a 4Fe-4S iron-sulfur cluster via tetrakis-L-cysteinyl tetrairon tetrasulfide.	tmpzr1t_l9r_go_relaxed.owl	iron incorporation into iron-sulphur cluster via tetrakis-L-cysteinyl tetrairon tetrasulphide				RESID:AA0140									biological_process											owl:Class	
GO:0018133	biolink:NamedThing	peptide cross-linking via L-cysteine oxazolinecarboxylic acid	The chemical reactions and pathways resulting in the formation of a peptidyl serine-peptidyl cysteine cross-link by the condensation of a serine hydroxyl with the carbonyl of the preceding residue.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0239									biological_process											owl:Class	
GO:0010705	biolink:NamedThing	meiotic DNA double-strand break processing involved in reciprocal meiotic recombination	The cell cycle process in which the 5' to 3' exonucleolytic resection of the DNA at the site of the break to form a 3' single-strand DNA overhang occurs resulting in double strand break formation and repair through a double Holliday junction intermediate.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0000706	biolink:NamedThing	meiotic DNA double-strand break processing	The cell cycle process in which the 5' to 3' exonucleolytic resection of the DNA at the site of the break to form a 3' single-strand DNA overhang occurs. This takes place during meiosis.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1902256	biolink:NamedThing	regulation of apoptotic process involved in outflow tract morphogenesis	Any process that modulates the frequency, rate or extent of apoptotic process involved in outflow tract morphogenesis.	tmpzr1t_l9r_go_relaxed.owl	regulation of apoptosis involved in outflow tract morphogenesis							dph	2013-06-24T19:12:24Z					biological_process											owl:Class	
GO:1990210	biolink:NamedThing	positive regulation by symbiont of indole acetic acid levels in host	Any process in which an organism activates, maintains or increases the frequency, rate or extent of the indole acetic acid levels in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	positive regulation by symbiont of IAA levels in host|positive regulation by symbiont of auxin levels in host							ml	2013-10-09T18:54:11Z					biological_process											owl:Class	
GO:0044032	biolink:NamedThing	modulation by symbiont of indole acetic acid levels in host	The alteration by an organism of the levels of indole acetic acid in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	modulation by symbiont of IAA levels in host|modulation by symbiont of auxin levels in host					Note that this term is intended for use in annotation of symbiont gene products. For host gene products that regulate indole acetic acid levels in the host, consider annotating to 'auxin homeostasis ; GO:0010252'.								biological_process											owl:Class	
GO:0046939	biolink:NamedThing	nucleotide phosphorylation	The process of introducing one or more phosphate groups into a nucleotide to produce a phosphorylated nucleoside.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0002929	biolink:NamedThing	MECO complex	A highly stable complex composed of the ATAC complex and the mediator complex (also called TRAP or MED). MECO binds and regulates the transcription of a subset of non-coding RNAs transcribed by RNA polymerase II.	tmpzr1t_l9r_go_relaxed.owl	meta-coactivator complex							hjd	2012-03-14T02:50:13Z					cellular_component											owl:Class	
GO:0034184	biolink:NamedThing	positive regulation of maintenance of mitotic sister chromatid cohesion	Any process that increases the extent to which the association between sister chromatids of a replicated chromosome is maintained during a mitotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0052335	biolink:NamedThing	modification by host of symbiont cytoskeleton	The process in which an organism effects a change in the structure or function of the symbiont cytoskeleton. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0140484	biolink:NamedThing	5-aminolevulinic acid import across plasma membrane	The directed movement of 5-aminolevulinic acid from outside of a cell, across the plasma membrane and into the cytosol.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/19527						pg	2020-06-29T08:59:24Z					biological_process											owl:Class	
GO:0103036	biolink:NamedThing	NADH:menaquinone oxidoreductase activity	Catalysis of the reaction: 5 H+ + NADH + a menaquinone <=> 4 H+ + NAD + a menaquinol.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN0-5388									molecular_function											owl:Class	
GO:0016655	biolink:NamedThing	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces a quinone or a similar acceptor molecule.	tmpzr1t_l9r_go_relaxed.owl	oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor				EC:1.6.5.-									molecular_function											owl:Class	
GO:0004365	biolink:NamedThing	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity	Catalysis of the reaction: D-glyceraldehyde 3-phosphate + phosphate + NAD+ = 3-phospho-D-glyceroyl phosphate + NADH + H+.	tmpzr1t_l9r_go_relaxed.owl	phosphoglyceraldehyde dehydrogenase activity|glyceraldehyde-3-P-dehydrogenase activity|triosephosphate dehydrogenase activity|NAD-dependent glyceraldehyde-3-phosphate dehydrogenase activity|NADH-glyceraldehyde phosphate dehydrogenase activity|D-glyceraldehyde-3-phosphate:NAD+ oxidoreductase (phosphorylating)|3-phosphoglyceraldehyde dehydrogenase activity|glyceraldehyde phosphate dehydrogenase (NAD)|dehydrogenase, glyceraldehyde phosphate|GAPDH activity|NAD-dependent glyceraldehyde phosphate dehydrogenase activity				RHEA:10300|Reactome:R-HSA-70449|MetaCyc:GAPOXNPHOSPHN-RXN|Reactome:R-HSA-70482|EC:1.2.1.12									molecular_function											owl:Class	
GO:0061628	biolink:NamedThing	H3K27me3 modified histone binding	Binding to a histone H3 in which the lysine residue at position 27 has been modified by trimethylation.	tmpzr1t_l9r_go_relaxed.owl	H3-K27me3 modified histone binding							dph	2014-05-14T15:36:53Z					molecular_function											owl:Class	
GO:0019788	biolink:NamedThing	NEDD8 transferase activity	Catalysis of the transfer of NEDD8 from one protein to another via the reaction X-NEDD8 + Y --> Y-NEDD8 + X, where both X-NEDD8 and Y-NEDD8 are covalent linkages.	tmpzr1t_l9r_go_relaxed.owl	NEDD8 conjugating enzyme activity|RUB1 conjugating enzyme activity|Hub1 conjugating enzyme activity				Reactome:R-HSA-8951764|Reactome:R-HSA-8952618|Reactome:R-HSA-8956025|Reactome:R-HSA-8952638|Reactome:R-HSA-8951661|Reactome:R-HSA-8951648|Reactome:R-HSA-8952044							GO:0019945|GO:0016976|GO:0042295		molecular_function											owl:Class	
GO:0019787	biolink:NamedThing	ubiquitin-like protein transferase activity	Catalysis of the transfer of a ubiquitin-like from one protein to another via the reaction X-ULP + Y --> Y-ULP + X, where both X-ULP and Y-ULP are covalent linkages. ULP represents a ubiquitin-like protein.	tmpzr1t_l9r_go_relaxed.owl	ubiquitin-like conjugating enzyme activity|E3|small conjugating protein transferase activity|small conjugating protein ligase activity|ubiquitin-like-protein ligase activity|E2|small protein conjugating enzyme activity				Reactome:R-HSA-5678490|Reactome:R-HSA-688137							GO:0008640|GO:0008639		molecular_function											owl:Class	
GO:0071155	biolink:NamedThing	G-protein alpha(13)-synembrin complex	A protein complex formed by the association of the guanine nucleotide exchange factor synembrin with the alpha(13) subunit of a heterotrimeric G protein.	tmpzr1t_l9r_go_relaxed.owl	Ric-8A G alpha 13 subunit complex							mah	2009-11-16T05:01:55Z					cellular_component											owl:Class	
GO:0034143	biolink:NamedThing	regulation of toll-like receptor 4 signaling pathway	Any process that modulates the frequency, rate, or extent of toll-like receptor 4 signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	regulation of toll-like receptor 4 signalling pathway|regulation of TLR4 signaling pathway													biological_process											owl:Class	
GO:0016720	biolink:NamedThing	delta12-fatty acid dehydrogenase activity	Catalysis of the reaction: AH(2) + linoleate + O(2) = A + crepenynate + 2 H(2)O.	tmpzr1t_l9r_go_relaxed.owl	linoleate delta12-fatty acid acetylenase (desaturase)|delta12 fatty acid acetylenase activity|delta-12 fatty acid acetylenase activity|linoleate delta-12-fatty acid acetylenase (desaturase) activity|linoleate, hydrogen-donor:oxygen oxidoreductase (Delta12-unsaturating)|crepenynate synthase activity|D12-fatty acid dehydrogenase activity				KEGG_REACTION:R05740|EC:1.14.99.33|RHEA:23456|MetaCyc:1.14.99.33-RXN									molecular_function											owl:Class	
GO:0033048	biolink:NamedThing	negative regulation of mitotic sister chromatid segregation	Any process that stops, prevents, or reduces the frequency, rate or extent of sister chromatid segregation during mitosis.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0102942	biolink:NamedThing	3,5-dimethoxyphenol O-methyltransferase activity	Catalysis of the reaction: 3,5-dimethoxyphenol + S-adenosyl-L-methionine  = H+ + 1,3,5-trimethoxybenzene + S-adenosyl-L-homocysteine.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-9022									molecular_function											owl:Class	
GO:0019385	biolink:NamedThing	methanogenesis, from acetate	The formation of methane, a colorless, odorless, flammable gas with the formula CH4, from other components, including acetate.	tmpzr1t_l9r_go_relaxed.owl	methane biosynthetic process from acetate|methane biosynthesis from acetate				MetaCyc:METH-ACETATE-PWY									biological_process											owl:Class	
GO:0047768	biolink:NamedThing	carboxy-cis,cis-muconate cyclase activity	Catalysis of the reaction: 3-carboxy-2,5-dihydro-5-oxofuran-2-acetate = 3-carboxy-cis,cis-muconate.	tmpzr1t_l9r_go_relaxed.owl	3-carboxy-cis,cis-muconate lactonizing enzyme activity|3-carboxymuconate cyclase activity|3-carboxy-2,5-dihydro-5-oxofuran-2-acetate lyase (decyclizing)				EC:5.5.1.5|KEGG_REACTION:R03308|RHEA:14977|MetaCyc:CARBOXY-CISCIS-MUCONATE-CYCLASE-RXN									molecular_function											owl:Class	
GO:0003333	biolink:NamedThing	amino acid transmembrane transport	The process in which an amino acid is transported across a membrane.	tmpzr1t_l9r_go_relaxed.owl	amino acid membrane transport					Note that this term is not intended for use in annotating lateral movement within membranes.		dph	2009-11-02T02:36:11Z					biological_process											owl:Class	
GO:0033594	biolink:NamedThing	response to hydroxyisoflavone	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydroxyisoflavone stimulus.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0035680	biolink:NamedThing	posterior lateral line neuromast hair cell morphogenesis	The change in form (cell shape and size) that occurs when a posterior lateral line neuromast hair cell progresses from its initial formation to its mature state. A neuromast hair cell is a hair cell that acts as a sensory receptor of the neuromast; it is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-02-14T11:08:14Z					biological_process											owl:Class	
GO:0035678	biolink:NamedThing	neuromast hair cell morphogenesis	The change in form (cell shape and size) that occurs when a neuromast hair cell progresses from its initial formation to its mature state. A neuromast hair cell is a hair cell that acts as a sensory receptor of the neuromast; it is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-02-14T11:06:15Z					biological_process											owl:Class	
GO:0002857	biolink:NamedThing	positive regulation of natural killer cell mediated immune response to tumor cell	Any process that activates or increases the frequency, rate, or extent of natural killer cell mediated immune response to a tumor cell.	tmpzr1t_l9r_go_relaxed.owl	up regulation of natural killer cell mediated immune response to tumor cell|upregulation of natural killer cell mediated immune response to tumor cell|stimulation of natural killer cell mediated immune response to tumor cell|activation of natural killer cell mediated immune response to tumor cell|up-regulation of natural killer cell mediated immune response to tumor cell													biological_process											owl:Class	
GO:0048697	biolink:NamedThing	positive regulation of collateral sprouting in absence of injury	Any process that activates or increases the frequency, rate or extent of collateral sprouting in the absence of injury.	tmpzr1t_l9r_go_relaxed.owl	stimulation of collateral sprouting in the absence of injury|up-regulation of collateral sprouting in the absence of injury|up regulation of collateral sprouting in the absence of injury|upregulation of collateral sprouting in the absence of injury|activation of collateral sprouting in the absence of injury													biological_process											owl:Class	
GO:0048672	biolink:NamedThing	positive regulation of collateral sprouting	Any process that activates or increases the frequency, rate or extent of collateral sprouting.	tmpzr1t_l9r_go_relaxed.owl	upregulation of collateral sprouting|up regulation of collateral sprouting|up-regulation of collateral sprouting|stimulation of collateral sprouting|activation of collateral sprouting													biological_process											owl:Class	
GO:0061472	biolink:NamedThing	karyomere membrane fusion	Process whereby karyomere membranes fuse during interphase to form a single lobed nucleus.	tmpzr1t_l9r_go_relaxed.owl								dph	2012-11-02T09:25:41Z					biological_process											owl:Class	
GO:1990543	biolink:NamedThing	mitochondrial S-adenosyl-L-methionine transmembrane transport	The process in which S-adenosyl-L-methionine is transported across a mitochondrial membrane, into or out of the mitochondrion.	tmpzr1t_l9r_go_relaxed.owl								vw	2014-11-19T11:26:27Z					biological_process											owl:Class	
GO:0006091	biolink:NamedThing	generation of precursor metabolites and energy	The chemical reactions and pathways resulting in the formation of precursor metabolites, substances from which energy is derived, and any process involved in the liberation of energy from these substances.	tmpzr1t_l9r_go_relaxed.owl	energy pathways|metabolic energy generation|intermediary metabolism													biological_process											owl:Class	
GO:0035804	biolink:NamedThing	structural constituent of egg coat	The action of a molecule that contributes to the structural integrity of an egg coat. An egg coat is a specialized extracellular matrix that surrounds the ovum of animals. The egg coat provides structural support and can play an essential role in oogenesis, fertilization and early development.	tmpzr1t_l9r_go_relaxed.owl	structural constituent of vitelline envelope|structural constituent of zona pellucida							bf	2011-04-19T01:56:06Z					molecular_function											owl:Class	
GO:0005201	biolink:NamedThing	extracellular matrix structural constituent	The action of a molecule that contributes to the structural integrity of the extracellular matrix.	tmpzr1t_l9r_go_relaxed.owl	core matrisome|core extracellular matrix|extracellular matrix glycoprotein					Extracellular matrix glycoproteins may be annotated to this term. PMID:24443019								molecular_function											owl:Class	
GO:0046963	biolink:NamedThing	3'-phosphoadenosine 5'-phosphosulfate transport	The directed movement of 3'-phosphoadenosine 5'-phosphosulfate, a naturally occurring mixed anhydride synthesized from adenosine 5'-phosphosulfate, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	PAPS transport|adenosine 3'-phosphate 5'-phosphosulfate transport|3'-phosphoadenosine 5'-phosphosulphate transport													biological_process											owl:Class	
GO:1904571	biolink:NamedThing	positive regulation of selenocysteine incorporation	Any process that activates or increases the frequency, rate or extent of selenocysteine incorporation.	tmpzr1t_l9r_go_relaxed.owl	activation of selenocysteine incorporation|up-regulation of selenocysteine incorporation|up regulation of selenocysteine incorporation|upregulation of selenocysteine incorporation							sl	2015-08-19T17:26:50Z					biological_process											owl:Class	
GO:0045901	biolink:NamedThing	positive regulation of translational elongation	Any process that activates or increases the frequency, rate or extent of translational elongation.	tmpzr1t_l9r_go_relaxed.owl	stimulation of translational elongation|upregulation of translational elongation|up regulation of translational elongation|activation of translational elongation|up-regulation of translational elongation													biological_process											owl:Class	
GO:0001949	biolink:NamedThing	sebaceous gland cell differentiation	The process in which a relatively unspecialized epidermal cell acquires the specialized features of a sebaceous gland cell.	tmpzr1t_l9r_go_relaxed.owl	sebocytes differentiation													biological_process											owl:Class	
GO:1901194	biolink:NamedThing	negative regulation of formation of translation preinitiation complex	Any process that stops, prevents or reduces the frequency, rate or extent of formation of translation preinitiation complex.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of formation of translation preinitiation complex|down regulation of formation of translation preinitiation complex|inhibition of translation preinitiation complex assembly|inhibition of formation of translation pre-initiation complex|down regulation of formation of translation pre-initiation complex|down regulation of translation preinitiation complex assembly|down-regulation of formation of translation pre-initiation complex|negative regulation of translation preinitiation complex assembly|down-regulation of translation preinitiation complex assembly|downregulation of formation of translation pre-initiation complex|downregulation of translation preinitiation complex assembly|inhibition of formation of translation preinitiation complex|downregulation of formation of translation preinitiation complex|negative regulation of formation of translation pre-initiation complex							ss	2012-07-25T02:31:41Z					biological_process											owl:Class	
GO:1904689	biolink:NamedThing	negative regulation of cytoplasmic translational initiation	Any process that stops, prevents or reduces the frequency, rate or extent of cytoplasmic translational initiation.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of cytoplasmic translational initiation|downregulation of cytoplasmic translational initiation|inhibition of cytoplasmic translational initiation|down regulation of cytoplasmic translational initiation							dos	2015-09-25T14:39:44Z					biological_process											owl:Class	
GO:0120297	biolink:NamedThing	histone dopaminyltransferase activity	Catalysis of the reaction: dopamine + L-glutaminyl-[histone] = 5-dopaminyl-L-glutamyl-[histone] + NH4(+).	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/20685						krc	2021-01-19T03:17:13Z					molecular_function											owl:Class	
GO:0120296	biolink:NamedThing	peptide dopaminyltransferase activity	Catalysis of the reaction: dopamine + L-glutaminyl-[protein] = 5-dopaminyl-L-glutamyl-[protein] + NH4(+).	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/20685			RHEA:66556			krc	2021-01-19T02:20:30Z					molecular_function											owl:Class	
GO:0007313	biolink:NamedThing	maternal specification of dorsal/ventral axis, oocyte, soma encoded	Polarization of the oocyte along the dorsal-ventral axis, by a gene product encoded by somatic cells. An example of this is found in Drosophila melanogaster.	tmpzr1t_l9r_go_relaxed.owl	maternal specification of dorsoventral axis, oocyte, soma encoded|maternal specification of dorsal-ventral axis, oocyte, soma encoded|maternal determination of dorsal/ventral axis, oocyte, soma encoded											GO:0048125		biological_process											owl:Class	
GO:0007310	biolink:NamedThing	oocyte dorsal/ventral axis specification	The establishment, maintenance and elaboration of the dorsal/ventral axis of the oocyte. An example of this is found in Drosophila melanogaster.	tmpzr1t_l9r_go_relaxed.owl	oocyte dorsal/ventral axis determination|oocyte dorsoventral axis specification|oocyte dorsal-ventral axis specification											GO:0048123|GO:0008072		biological_process											owl:Class	
GO:2001308	biolink:NamedThing	gliotoxin metabolic process	The chemical reactions and pathways involving the epipolythiodioxopiperazine gliotoxin, a poisonous substance produced by some species of fungi.	tmpzr1t_l9r_go_relaxed.owl	gliotoxin metabolism							pr	2012-03-15T03:42:10Z					biological_process											owl:Class	
GO:1900273	biolink:NamedThing	positive regulation of long-term synaptic potentiation	Any process that activates or increases the frequency, rate or extent of long-term synaptic potentiation.	tmpzr1t_l9r_go_relaxed.owl	up regulation of long-term potentiation|upregulation of LTP|up regulation of long-term synaptic potentiation|activation of long-term potentiation|positive regulation of LTP|up-regulation of long-term potentiation|activation of LTP|up-regulation of LTP|upregulation of long-term potentiation|up-regulation of long-term synaptic potentiation|up regulation of LTP|activation of long-term synaptic potentiation|upregulation of long-term synaptic potentiation|positive regulation of long-term potentiation							rl	2012-04-04T07:17:30Z					biological_process											owl:Class	
GO:1903603	biolink:NamedThing	thermospermine biosynthetic process	The chemical reactions and pathways resulting in the formation of thermospermine.	tmpzr1t_l9r_go_relaxed.owl	thermospermine anabolism|thermospermine formation|thermospermine biosynthesis|thermospermine synthesis							tb	2014-11-12T18:48:12Z					biological_process											owl:Class	
GO:0006596	biolink:NamedThing	polyamine biosynthetic process	The chemical reactions and pathways resulting in the formation of polyamines, any organic compound containing two or more amino groups.	tmpzr1t_l9r_go_relaxed.owl	polyamine synthesis|polyamine biosynthesis|polyamine anabolism|polyamine formation				MetaCyc:POLYAMSYN-PWY									biological_process											owl:Class	
GO:1900713	biolink:NamedThing	regulation of violaceol I biosynthetic process	Any process that modulates the frequency, rate or extent of violaceol I biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of violaceol I biosynthesis|regulation of violaceol I synthesis|regulation of violaceol I formation|regulation of violaceol I anabolism							di	2012-05-22T05:04:12Z					biological_process											owl:Class	
GO:0005592	biolink:NamedThing	collagen type XI trimer	A collagen heterotrimer containing type XI alpha chains in alpha1(XI)alpha2(XI)alpha3(XI) trimers; type XI collagen triple helices associate to form fibrils.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0005583	biolink:NamedThing	fibrillar collagen trimer	Any triple helical collagen trimer that forms fibrils.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0042433	biolink:NamedThing	indole catabolic process	The chemical reactions and pathways resulting in the breakdown of indole (2,3-benzopyrrole), the basis of many biologically active substances (e.g. serotonin, tryptophan).	tmpzr1t_l9r_go_relaxed.owl	indole breakdown|indole catabolism|indole degradation													biological_process											owl:Class	
GO:0042436	biolink:NamedThing	indole-containing compound catabolic process	The chemical reactions and pathways resulting in the breakdown of compounds that contain an indole (2,3-benzopyrrole) skeleton.	tmpzr1t_l9r_go_relaxed.owl	indole derivative catabolism|indole derivative catabolic process|indole-containing compound degradation|indole-containing compound catabolism|indole-containing compound breakdown													biological_process											owl:Class	
GO:0015251	biolink:NamedThing	ammonium channel activity	Enables the facilitated diffusion of ammonium (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0008519	biolink:NamedThing	ammonium transmembrane transporter activity	Enables the transfer of ammonium from one side of a membrane to the other. Ammonium is the cation NH4+ which is formed from N2 by root-nodule bacteria in leguminous plants and is an excretory product in ammonotelic animals.	tmpzr1t_l9r_go_relaxed.owl	ammonia transmembrane transporter activity				Reactome:R-HSA-446277|Reactome:R-HSA-444393|Reactome:R-HSA-446278|Reactome:R-HSA-5623051|RHEA:28747|Reactome:R-HSA-444416|Reactome:R-HSA-444419							GO:0051739		molecular_function											owl:Class	
GO:0071457	biolink:NamedThing	cellular response to ozone	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ozone stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-12-16T04:45:59Z					biological_process											owl:Class	
GO:0010193	biolink:NamedThing	response to ozone	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ozone stimulus.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0047839	biolink:NamedThing	dATP(dGTP)-DNA purinetransferase activity	Catalysis of the reaction: dATP + depurinated DNA = ribose triphosphate + DNA.	tmpzr1t_l9r_go_relaxed.owl	dATP(dGTP):depurinated-DNA purine transferase activity|dATP(dGTP)--DNA purine transferase activity				EC:2.6.99.1|MetaCyc:DATPDGTP--DNA-PURINE-TRANSFERASE-RXN									molecular_function											owl:Class	
GO:0016769	biolink:NamedThing	transferase activity, transferring nitrogenous groups	Catalysis of the transfer of a nitrogenous group from one compound (donor) to another (acceptor).	tmpzr1t_l9r_go_relaxed.owl	transferase activity, transferring other nitrogenous groups				EC:2.6.-.-									molecular_function											owl:Class	
GO:1902842	biolink:NamedThing	negative regulation of netrin-activated signaling pathway	Any process that stops, prevents or reduces the frequency, rate or extent of netrin-activated signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	inhibition of netrin-activated signaling pathway|negative regulation of netrin signaling pathway|downregulation of netrin-activated signalling pathway|downregulation of netrin signaling pathway|down regulation of netrin-activated signal transduction pathway|downregulation of netrin-activated signal transduction pathway|downregulation of netrin-activated signaling pathway|down-regulation of netrin-activated signalling pathway|down-regulation of netrin-mediated signaling pathway|inhibition of netrin-activated signalling pathway|negative regulation of netrin-activated signal transduction pathway|down regulation of netrin-mediated signaling pathway|negative regulation of netrin-mediated signaling pathway|down regulation of netrin signaling pathway|down-regulation of netrin-activated signal transduction pathway|inhibition of netrin signaling pathway|downregulation of netrin-mediated signaling pathway|down regulation of netrin-activated signaling pathway|down-regulation of netrin-activated signaling pathway|negative regulation of netrin-activated signalling pathway|down-regulation of netrin signaling pathway|inhibition of netrin-activated signal transduction pathway|inhibition of netrin-mediated signaling pathway|down regulation of netrin-activated signalling pathway							kmv	2014-04-01T15:25:33Z					biological_process											owl:Class	
GO:0005863	biolink:NamedThing	striated muscle myosin thick filament	Bipolar filaments formed of polymers of a muscle-specific myosin II isoform, found in the middle of sarcomeres in myofibrils.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0032982	biolink:NamedThing	myosin filament	A supramolecular fiber containing myosin heavy chains, plus associated light chains and other proteins, in which the myosin heavy chains are arranged into a filament.	tmpzr1t_l9r_go_relaxed.owl	myosin thick filament|thick filament													cellular_component											owl:Class	
GO:0008840	biolink:NamedThing	4-hydroxy-tetrahydrodipicolinate synthase activity	Catalysis of the reaction: pyruvate + L-aspartate-4-semialdehyde = (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + H2O.	tmpzr1t_l9r_go_relaxed.owl	L-aspartate-4-semialdehyde hydro-lyase (adding pyruvate and cyclizing)|dihydrodipicolinate synthase activity|DHDPS activity|dihydrodipicolinate synthetase activity|dihydropicolinate synthetase activity|dihydrodipicolinic acid synthase activity|L-aspartate-4-semialdehyde hydro-lyase [adding pyruvate and cyclizing; (S)-2,3-dihydropyridine-2,6-dicarboxylate-forming]				KEGG_REACTION:R02292|MetaCyc:DIHYDRODIPICSYN-RXN|RHEA:14845|EC:4.3.3.7									molecular_function											owl:Class	
GO:0050797	biolink:NamedThing	thymidylate synthase (FAD) activity	Catalysis of the reaction: 5,10-methylenetetrahydrofolate + dUMP + NADPH + H+ = dTMP + tetrahydrofolate + NADP+.	tmpzr1t_l9r_go_relaxed.owl	Thy1 activity|flavin dependent thymidylate synthase activity|ThyX activity|5,10-methylenetetrahydrofolate,FADH2:dUMP C-methyltransferase activity|FDTS activity				RHEA:29043|EC:2.1.1.148|MetaCyc:RXN-8850|KEGG_REACTION:R06613									molecular_function											owl:Class	
GO:0042083	biolink:NamedThing	5,10-methylenetetrahydrofolate-dependent methyltransferase activity	Catalysis of the transfer of a methyl group to an acceptor molecule; dependent on the presence of 5,10-methylenetetrahydrofolate.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0042883	biolink:NamedThing	cysteine transport	The directed movement of cysteine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	L-cysteine transport													biological_process											owl:Class	
GO:0019172	biolink:NamedThing	glyoxalase III activity	Catalysis of the reaction: methylglyoxal + H2O = D-lactate.	tmpzr1t_l9r_go_relaxed.owl	(R)-lactate hydro-lyase|D-lactate dehydratase|glutathione-independent glyoxalase activity				RHEA:27754|MetaCyc:GLYOXIII-RXN|EC:4.2.1.130	Note that this term was reinstated from obsolete. Also note that this enzymatic activity converts methylglyoxal to D-lactate in a single glutathione (GSH)-independent step. The other known route for this conversion is the two-step GSH-dependent pathway catalyzed by EC:4.4.1.5 (lactoylglutathione lyase) and EC:3.1.2.6 (hydroxyacylglutathione hydrolase).								molecular_function											owl:Class	
GO:0120137	biolink:NamedThing	positive regulation of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity	Any process that activates or increases the frequency or rate of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity.	tmpzr1t_l9r_go_relaxed.owl								krc	2018-03-21T21:59:55Z					biological_process											owl:Class	
GO:0006437	biolink:NamedThing	tyrosyl-tRNA aminoacylation	The process of coupling tyrosine to tyrosyl-tRNA, catalyzed by tyrosyl-tRNA synthetase. The tyrosyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2'-OH group of a tyrosine-accetping tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0033560	biolink:NamedThing	folate reductase activity	Catalysis of the reaction: 7,8-dihydrofolate + NADP+ = folate + NADPH + H+.	tmpzr1t_l9r_go_relaxed.owl					RHEA:31103|Reactome:R-HSA-197963|Reactome:R-HSA-197972									molecular_function											owl:Class	
GO:0071866	biolink:NamedThing	negative regulation of apoptotic process in bone marrow cell	Any process that stops, prevents, or reduces the frequency, rate or extent of the occurrence or rate of cell death by apoptotic process in the bone marrow.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of apoptosis in bone marrow|down-regulation of apoptosis in bone marrow|inhibition of apoptosis in bone marrow|down regulation of apoptosis in bone marrow|negative regulation of bone marrow cell apoptosis|negative regulation of killing of bone marrow cells|downregulation of apoptosis in bone marrow|negative regulation of apoptotic process in bone marrow|negative regulation of bone marrow cell programmed cell death by apoptosis|negative regulation of programmed cell death, bone marrow cells|negative regulation of programmed cell death of bone marrow cells by apoptosis							mah	2010-09-13T02:17:38Z					biological_process											owl:Class	
GO:0010519	biolink:NamedThing	negative regulation of phospholipase activity	Any process that decreases the frequency, rate or extent of phospholipase activity, the hydrolysis of a phospholipid.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0060192	biolink:NamedThing	negative regulation of lipase activity	Any process that decreases the frequency, rate or extent of lipase activity, the hydrolysis of a lipid or phospholipid.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0010322	biolink:NamedThing	regulation of isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of isopentenyl diphosphate produced via the methylerythritol (MEP) pathway (mevalonate-independent).	tmpzr1t_l9r_go_relaxed.owl	regulation of isopentenyl diphosphate biosynthetic process, mevalonate-independent pathway													biological_process											owl:Class	
GO:0102823	biolink:NamedThing	kaempferol-3-rhamnoside-glucosyltransferase activity	Catalysis of the reaction: UDP-alpha-D-glucose + kaempferol-3-rhamnoside <=> kaempferol 3-O-rhamnoside-7-O-glucoside + UDP.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-8266									molecular_function											owl:Class	
GO:2000358	biolink:NamedThing	positive regulation of kidney smooth muscle cell differentiation	Any process that activates or increases the frequency, rate or extent of kidney smooth muscle cell differentiation.	tmpzr1t_l9r_go_relaxed.owl								yaf	2011-02-03T02:14:31Z					biological_process											owl:Class	
GO:0098880	biolink:NamedThing	maintenance of postsynaptic specialization structure	A process which maintains the organization and the arrangement of proteins in the presynaptic specialization.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0033351	biolink:NamedThing	UDP-D-apiose metabolic process	The chemical reactions and pathways involving UDP-D-apiose, uridinediphosphoapiose, a substance composed of apiose in glycosidic linkage with uridine diphosphate.	tmpzr1t_l9r_go_relaxed.owl	UDP-D-apiose metabolism													biological_process											owl:Class	
GO:0009225	biolink:NamedThing	nucleotide-sugar metabolic process	The cellular chemical reactions and pathways involving nucleotide-sugars, any nucleotide-carbohydrate in which the distal phosphoric residue of a nucleoside 5'-diphosphate is in glycosidic linkage with a monosaccharide or monosaccharide derivative.	tmpzr1t_l9r_go_relaxed.owl	nucleotide-sugar metabolism	https://github.com/geneontology/go-ontology/issues/14587												biological_process											owl:Class	
GO:1902770	biolink:NamedThing	negative regulation of choline O-acetyltransferase activity	Any process that stops, prevents or reduces the frequency, rate or extent of choline O-acetyltransferase activity.	tmpzr1t_l9r_go_relaxed.owl	downregulation of choline acetyltransferase activity|down-regulation of choline O-acetyltransferase activity|downregulation of acetyl-CoA:choline O-acetyltransferase activity|downregulation of CHOACTase activity|inhibition of acetyl-CoA:choline O-acetyltransferase activity|down-regulation of acetyl-CoA:choline O-acetyltransferase activity|inhibition of CHOACTase activity|down regulation of choline acetylase activity|negative regulation of choline acetylase activity|negative regulation of CHOACTase activity|negative regulation of acetyl-CoA:choline O-acetyltransferase activity|down regulation of choline acetyltransferase activity|down regulation of CHOACTase activity|down-regulation of choline acetylase activity|inhibition of choline acetylase activity|downregulation of choline acetylase activity|inhibition of choline O-acetyltransferase activity|negative regulation of choline acetyltransferase activity|downregulation of choline O-acetyltransferase activity|inhibition of choline acetyltransferase activity|down regulation of acetyl-CoA:choline O-acetyltransferase activity|down-regulation of CHOACTase activity|down regulation of choline O-acetyltransferase activity|down-regulation of choline acetyltransferase activity							mr	2014-03-11T18:56:50Z					biological_process											owl:Class	
GO:1902769	biolink:NamedThing	regulation of choline O-acetyltransferase activity	Any process that modulates the frequency, rate or extent of choline O-acetyltransferase activity.	tmpzr1t_l9r_go_relaxed.owl	regulation of CHOACTase activity|regulation of acetyl-CoA:choline O-acetyltransferase activity|regulation of choline acetylase activity|regulation of choline acetyltransferase activity							mr	2014-03-11T18:54:26Z					biological_process											owl:Class	
GO:0120066	biolink:NamedThing	pyloric canal smooth muscle contraction	A process in which force is generated within gastric smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the distal part of the pylorus between the pyloric antrum and the pyloric sphincter.	tmpzr1t_l9r_go_relaxed.owl								krc	2017-06-13T22:37:51Z					biological_process											owl:Class	
GO:0120064	biolink:NamedThing	stomach pylorus smooth muscle contraction	A process in which force is generated within gastric smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the most distal part of the stomach.	tmpzr1t_l9r_go_relaxed.owl								krc	2017-06-13T22:32:04Z					biological_process											owl:Class	
GO:1902045	biolink:NamedThing	negative regulation of Fas signaling pathway	Any process that stops, prevents or reduces the frequency, rate or extent of Fas signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	down regulation of FasR signaling pathway|down-regulation of Fas receptor signaling pathway|down-regulation of FasL signaling pathway|inhibition of CD95 signaling pathway|down-regulation of Fas-FasL signaling pathway|down regulation of Fas receptor signaling pathway|down regulation of Fas-FasL signaling pathway|down regulation of Fas signaling pathway|down regulation of Apo-1 signaling pathway|inhibition of Apo-1 signaling pathway|down-regulation of FasR signaling pathway|down-regulation of Apo-1 signaling pathway|down-regulation of Fas signaling pathway|negative regulation of Apo-1 signaling pathway|inhibition of FasR signaling pathway|downregulation of FasL signaling pathway|down regulation of FasL signaling pathway|down regulation of FAS ligand-Fas signaling pathway|downregulation of Apo-1 signaling pathway|inhibition of Fas receptor signaling pathway|down-regulation of FAS ligand-Fas signaling pathway|downregulation of FasR signaling pathway|downregulation of FAS ligand-Fas signaling pathway|negative regulation of FasL signaling pathway|inhibition of FAS ligand-Fas signaling pathway|down regulation of CD95 signaling pathway|inhibition of FasL signaling pathway|inhibition of Fas signaling pathway|downregulation of Fas-FasL signaling pathway|down-regulation of CD95 signaling pathway|negative regulation of FAS ligand-Fas signaling pathway|negative regulation of FasR signaling pathway|downregulation of CD95 signaling pathway|negative regulation of CD95 signaling pathway|negative regulation of Fas-FasL signaling pathway|downregulation of Fas signaling pathway|downregulation of Fas receptor signaling pathway|inhibition of Fas-FasL signaling pathway|negative regulation of Fas receptor signaling pathway							lb	2013-04-03T07:21:28Z					biological_process											owl:Class	
GO:0035788	biolink:NamedThing	cell migration involved in metanephros development	The orderly movement of a cell from one site to another that will contribute to the progression of the metanephric kidney over time, from its formation to the mature organ.	tmpzr1t_l9r_go_relaxed.owl	cell migration involved in metanephric kidney development							bf	2011-04-06T10:42:21Z					biological_process											owl:Class	
GO:0035787	biolink:NamedThing	cell migration involved in kidney development	The orderly movement of a cell from one site to another that will contribute to the progression of the kidney over time, from its formation to the mature organ.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-04-06T10:39:52Z					biological_process											owl:Class	
GO:1902345	biolink:NamedThing	positive regulation of maltose transport	Any process that activates or increases the frequency, rate or extent of maltose transport.	tmpzr1t_l9r_go_relaxed.owl	up regulation of maltose transport|upregulation of maltose transport|activation of maltose transport|up-regulation of maltose transport							dph	2013-08-01T17:16:34Z					biological_process											owl:Class	
GO:0099179	biolink:NamedThing	regulation of synaptic membrane adhesion	Any process that modulates the frequency, rate or extent of adhesion between pre- and post-synaptic membranes.	tmpzr1t_l9r_go_relaxed.owl	regulation of synapse adhesion between pre- and post-synapse													biological_process											owl:Class	
GO:0051107	biolink:NamedThing	negative regulation of DNA ligation	Any process that stops, prevents, or reduces the frequency, rate or extent of DNA ligation, the re-formation of a broken phosphodiester bond in the DNA backbone, carried out by DNA ligase.	tmpzr1t_l9r_go_relaxed.owl	downregulation of DNA ligation|down-regulation of DNA ligation|inhibition of DNA ligation|down regulation of DNA ligation													biological_process											owl:Class	
GO:0051053	biolink:NamedThing	negative regulation of DNA metabolic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving DNA.	tmpzr1t_l9r_go_relaxed.owl	down regulation of DNA metabolic process|inhibition of DNA metabolic process|negative regulation of DNA metabolism|downregulation of DNA metabolic process|down-regulation of DNA metabolic process													biological_process											owl:Class	
GO:0031981	biolink:NamedThing	nuclear lumen	The volume enclosed by the nuclear inner membrane.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0072729	biolink:NamedThing	cellular response to Gentian violet	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a Gentian violet stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to {4-[Bis-(4-dimethylamino-phenyl)-methylene]-cyclohexa-2,5-dienylidene}-dimethyl-ammonium chloride|cellular response to crystal violet							mah	2012-05-31T11:23:40Z					biological_process											owl:Class	
GO:0071310	biolink:NamedThing	cellular response to organic substance	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic substance stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-12-10T04:46:04Z					biological_process											owl:Class	
GO:0050102	biolink:NamedThing	cellodextrin phosphorylase activity	Catalysis of the reaction: 1,4-beta-D-glucosyl(n) + phosphate = 1,4-beta-D-glucosyl(n-1) + alpha-D-glucose 1-phosphate.	tmpzr1t_l9r_go_relaxed.owl	beta-1,4-oligoglucan:orthophosphate glucosyltransferase activity|1,4-beta-D-oligo-D-glucan:phosphate alpha-D-glucosyltransferase activity				EC:2.4.1.49|MetaCyc:CELLODEXTRIN-PHOSPHORYLASE-RXN|RHEA:23024									molecular_function											owl:Class	
GO:0009158	biolink:NamedThing	ribonucleoside monophosphate catabolic process	The chemical reactions and pathways resulting in the breakdown of a ribonucleoside monophosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with phosphate on the sugar.	tmpzr1t_l9r_go_relaxed.owl	ribonucleoside monophosphate degradation|ribonucleoside monophosphate catabolism|ribonucleoside monophosphate breakdown													biological_process											owl:Class	
GO:0009334	biolink:NamedThing	3-phenylpropionate dioxygenase complex	Enzyme complex consisting of four proteins: the two subunits of the hydroxylase component (hcaE and hcaF), a ferredoxin (hcaC) and a ferredoxin reductase (hcaD). Converts 3-phenylpropionic acid (PP) into cis-3-(3-carboxyethyl)-3,5-cyclohexadiene-1,2-diol (PP-dihydrodiol).	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:HCAMULTI-CPLX	See also the molecular function term '3-phenylpropionate dioxygenase activity ; GO:0008695'.								cellular_component											owl:Class	
GO:0051246	biolink:NamedThing	regulation of protein metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a protein.	tmpzr1t_l9r_go_relaxed.owl	regulation of protein metabolism													biological_process											owl:Class	
GO:0031428	biolink:NamedThing	box C/D RNP complex	A ribonucleoprotein complex containing a box C/D type RNA that can carry out ribose-2'-O-methylation of target RNAs. Box C/D type RNAs are widespread in eukaryotes and in Archaea, suggesting that an RNA-based guide mechanism for directing specific RNA 2'-O-ribose methylations was present in the common ancestor of Archaea and Eukarya.	tmpzr1t_l9r_go_relaxed.owl	box C/D sRNP complex|box C/D snoRNP complex|box C/D snoRNP ribose 2'-O methylase complex|box C/D snoRNP ribose-2'-O-methyltransferase complex|box C/D small nucleolar ribonucleoprotein complex	https://github.com/geneontology/go-ontology/issues/20416												cellular_component											owl:Class	
GO:0005732	biolink:NamedThing	sno(s)RNA-containing ribonucleoprotein complex	A ribonucleoprotein complex that contains an RNA molecule of the snoRNA family and associated proteins. Many are involved in a step of processing of rRNA molecules: cleavage, 2'-O-methylation, or pseudouridylation, but other RNA types can be targets as well. The majority fall into one of two classes, box C/D type or box H/ACA type, which are conserved across eukaryotes and archaea. Other members include the telomerase RNA and the ribonuclease MRP RNA.	tmpzr1t_l9r_go_relaxed.owl	small ribonucleoprotein protein complex|small nucleolar ribonucleoprotein|small ribonucleoprotein|small nucleolar ribonucleoprotein complex|snoRNP|sRNP	https://github.com/geneontology/go-ontology/issues/20416				Note that 'nucleolar' in the name acronym 'snoRNA' is part of the RNA family designation 'small nucleolar', and does not reflect the location of the complex. Both box C/D type and box H/ACA RNAs are found in Archaea (where they are referred to as sRNAs) as well as in Eukaryota. In eukaryotes, box H/ACA RNAs are found in both nucleolar-localized snoRNP complexes and in Cajal body-localized scaRNP complexes.								cellular_component											owl:Class	
GO:0042692	biolink:NamedThing	muscle cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a muscle cell.	tmpzr1t_l9r_go_relaxed.owl	myogenesis													biological_process											owl:Class	
GO:0060131	biolink:NamedThing	corticotropin hormone secreting cell development	The process whose specific outcome is the progression of a corticotropic hormone secreting cell over time, from its formation to the mature structure. An corticotropic hormone secreting cell is a basophil cell of the anterior pituitary that produces corticotropin.	tmpzr1t_l9r_go_relaxed.owl	corticotroph development|corticotrope development|adrenocorticotropic hormone secreting cell development|adrenocorticotrophic hormone secreting cell development|corticotrophin hormone secreting cell development													biological_process											owl:Class	
GO:0052709	biolink:NamedThing	N-alpha,N-alpha,N-alpha-trimethyl-L-histidine biosynthetic process	The chemical reactions and pathways resulting in the formation of N-alpha,N-alpha,N-alpha-trimethyl-L-histidine, also known as histidine betaine or hercynine, a trimethylated derivative of histidine.	tmpzr1t_l9r_go_relaxed.owl	histidine betaine synthesis|histidine betaine biosynthetic process|hercynine synthesis|hercynine biosynthetic process|N-alpha,N-alpha,N-alpha-trimethyl-L-histidine formation|histidine betaine formation|hercynine biosynthesis|hercynine anabolism|histidine betaine anabolism|hercynine formation|N-alpha,N-alpha,N-alpha-trimethyl-L-histidine anabolism|histidine betaine biosynthesis|N-alpha,N-alpha,N-alpha-trimethyl-L-histidine synthesis|N-alpha,N-alpha,N-alpha-trimethyl-L-histidine biosynthesis							ai	2011-08-05T02:22:05Z					biological_process											owl:Class	
GO:0019260	biolink:NamedThing	1,2-dichloroethane catabolic process	The chemical reactions and pathways resulting in the breakdown of 1,2-dichloroethane, a major commodity chemical used, for example, in the manufacture of vinyl chloride.	tmpzr1t_l9r_go_relaxed.owl	1,2-dichloroethane catabolism|1,2-dichloroethane breakdown|1,2-dichloroethane degradation				MetaCyc:12DICHLORETHDEG-PWY									biological_process											owl:Class	
GO:0042206	biolink:NamedThing	halogenated hydrocarbon catabolic process	The chemical reactions and pathways resulting in the breakdown of halogenated hydrocarbons, compounds derived from hydrocarbons by replacing one or more hydrogen atoms with halogen atoms.	tmpzr1t_l9r_go_relaxed.owl	halogenated hydrocarbon catabolism|halogenated hydrocarbon degradation|halogenated hydrocarbon breakdown													biological_process											owl:Class	
GO:1900786	biolink:NamedThing	naphtho-gamma-pyrone catabolic process	The chemical reactions and pathways resulting in the breakdown of naphtho-gamma-pyrone.	tmpzr1t_l9r_go_relaxed.owl	naphtho-gamma-pyrones catabolism|naphtho-gamma-pyrone degradation|naphtho-gamma-pyrones degradation|naphtho-gamma-pyrones catabolic process|naphtho-gamma-pyrone breakdown|naphtho-gamma-pyrone catabolism|naphtho-gamma-pyrones breakdown							di	2012-06-04T09:35:54Z					biological_process											owl:Class	
GO:0042182	biolink:NamedThing	ketone catabolic process	The chemical reactions and pathways resulting in the breakdown of ketones, a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups.	tmpzr1t_l9r_go_relaxed.owl	ketone catabolism|ketone degradation|ketone breakdown													biological_process											owl:Class	
GO:0014047	biolink:NamedThing	glutamate secretion	The controlled release of glutamate by a cell. The glutamate is the most abundant excitatory neurotransmitter in the nervous system.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1904540	biolink:NamedThing	positive regulation of glycolytic process through fructose-6-phosphate	Any process that activates or increases the frequency, rate or extent of glycolytic process through fructose-6-phosphate.	tmpzr1t_l9r_go_relaxed.owl	activation of glycolytic process through fructose-6-phosphate|positive regulation of glycolysis through fructose-6-phosphate|up regulation of glycolysis through fructose-6-phosphate|up-regulation of glycolytic process through fructose-6-phosphate|upregulation of glycolytic process through fructose-6-phosphate|upregulation of glycolysis through fructose-6-phosphate|up-regulation of glycolysis through fructose-6-phosphate|up regulation of glycolytic process through fructose-6-phosphate|activation of glycolysis through fructose-6-phosphate							dph	2015-08-07T11:35:22Z					biological_process											owl:Class	
GO:1904538	biolink:NamedThing	regulation of glycolytic process through fructose-6-phosphate	Any process that modulates the frequency, rate or extent of glycolytic process through fructose-6-phosphate.	tmpzr1t_l9r_go_relaxed.owl	regulation of glycolysis through fructose-6-phosphate							dph	2015-08-07T11:35:10Z					biological_process											owl:Class	
GO:2000942	biolink:NamedThing	regulation of amylopectin metabolic process	Any process that modulates the frequency, rate or extent of amylopectin metabolic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of Amylopectin metabolism							tt	2011-08-01T02:10:28Z					biological_process											owl:Class	
GO:2001193	biolink:NamedThing	positive regulation of gamma-delta T cell activation involved in immune response	Any process that activates or increases the frequency, rate or extent of gamma-delta T cell activation involved in immune response.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of gamma-delta T-lymphocyte activation during immune response|positive regulation of gamma-delta T-cell activation during immune response|positive regulation of gamma-delta T cell activation during immune response|positive regulation of gamma-delta T lymphocyte activation during immune response							yaf	2011-11-03T04:28:48Z					biological_process											owl:Class	
GO:0009148	biolink:NamedThing	pyrimidine nucleoside triphosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of pyrimidine nucleoside triphosphate, a compound consisting of a pyrimidine base linked to a ribose or deoxyribose sugar esterified with triphosphate on the sugar.	tmpzr1t_l9r_go_relaxed.owl	pyrimidine nucleoside triphosphate anabolism|pyrimidine nucleoside triphosphate biosynthesis|pyrimidine nucleoside triphosphate synthesis|pyrimidine nucleoside triphosphate formation													biological_process											owl:Class	
GO:0071504	biolink:NamedThing	cellular response to heparin	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heparin stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-12-18T03:34:38Z					biological_process											owl:Class	
GO:0006193	biolink:NamedThing	ITP catabolic process	The chemical reactions and pathways resulting in the breakdown of ITP, inosine (5'-)triphosphate.	tmpzr1t_l9r_go_relaxed.owl	ITP degradation|ITP hydrolysis|ITP breakdown|ITP catabolism													biological_process											owl:Class	
GO:0033133	biolink:NamedThing	positive regulation of glucokinase activity	Any process that activates or increases the frequency, rate or extent of glucokinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a glucose molecule.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of glucokinase activity|stimulation of glucokinase activity|glucokinase activator|upregulation of glucokinase activity|up regulation of glucokinase activity													biological_process											owl:Class	
GO:0033131	biolink:NamedThing	regulation of glucokinase activity	Any process that modulates the frequency, rate or extent of glucokinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a glucose molecule.	tmpzr1t_l9r_go_relaxed.owl	glucokinase regulator													biological_process											owl:Class	
GO:0045598	biolink:NamedThing	regulation of fat cell differentiation	Any process that modulates the frequency, rate or extent of adipocyte differentiation.	tmpzr1t_l9r_go_relaxed.owl	regulation of adipocyte cell differentiation|regulation of adipocyte differentiation													biological_process											owl:Class	
GO:2000166	biolink:NamedThing	negative regulation of planar cell polarity pathway involved in pericardium morphogenesis	Any process that stops, prevents, or reduces the frequency, rate or extent of planar cell polarity pathway involved in pericardium morphogenesis.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-10-05T01:07:39Z					biological_process											owl:Class	
GO:1901550	biolink:NamedThing	regulation of endothelial cell development	Any process that modulates the frequency, rate or extent of endothelial cell development.	tmpzr1t_l9r_go_relaxed.owl								pr	2012-10-30T12:59:50Z					biological_process											owl:Class	
GO:0045601	biolink:NamedThing	regulation of endothelial cell differentiation	Any process that modulates the frequency, rate or extent of endothelial cell differentiation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0051407	biolink:NamedThing	glycerone phosphate:inorganic phosphate antiporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glycerone phosphate(out) + phosphate(in) = glycerone phosphate(in) + phosphate(out).	tmpzr1t_l9r_go_relaxed.owl	dihydroxyacetone-phosphate:inorganic phosphate antiporter activity													molecular_function											owl:Class	
GO:0075300	biolink:NamedThing	negative regulation of zygospore formation	Any process that stops, prevents, or reduces the frequency, rate or extent of zygospore formation, a process in which a thick-walled spore of some algae and fungi is formed by union of two similar sexual cells, usually serves as a resting spore, and produces the sporophytic phase.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:2000449	biolink:NamedThing	regulation of CD8-positive, alpha-beta T cell extravasation	Any process that modulates the frequency, rate or extent of CD8-positive, alpha-beta T cell extravasation.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-03-04T10:41:03Z					biological_process											owl:Class	
GO:0021966	biolink:NamedThing	corticospinal neuron axon guidance	The process in which the migration of an axon growth cone of a neuron that is part of the corticospinal tract is directed from the cerebral cortex layer V to the spinal cord dorsal funiculus in response to a combination of attractive and repulsive cues.	tmpzr1t_l9r_go_relaxed.owl	corticospinal neuron axon pathfinding													biological_process											owl:Class	
GO:1990513	biolink:NamedThing	CLOCK-BMAL transcription complex	Transcription factor complex which interacts with E-box regulatory elements in target genes, including Period (Per1, Per2, Per3) and Cryptochrome (Cry1, Cry2), to activate their transcription during the daytime. The CRY-PER complexes inhibit CLOCK-BMAL1-driven transcription in a negative feedback loop to generate circadian rhythms.	tmpzr1t_l9r_go_relaxed.owl	CLOCK/BMAL complex					An example of this is CLOCK in human (O15516) in PMID:23229515 (inferred from physical interaction).		bhm	2014-10-08T13:10:24Z					cellular_component											owl:Class	
GO:1903622	biolink:NamedThing	regulation of RNA polymerase III activity	Any process that modulates the frequency, rate or extent of RNA polymerase III activity.	tmpzr1t_l9r_go_relaxed.owl	regulation of DNA-directed RNA polymerase activity involved in transcription from RNA polymerase III promoter							al	2014-11-19T18:24:29Z					biological_process											owl:Class	
GO:0006359	biolink:NamedThing	regulation of transcription by RNA polymerase III	Any process that modulates the frequency, rate or extent of transcription mediated by RNA ploymerase III.	tmpzr1t_l9r_go_relaxed.owl	regulation of transcription from Pol III promoter|regulation of transcription from RNA polymerase III promoter													biological_process											owl:Class	
GO:1900269	biolink:NamedThing	negative regulation of reverse transcription	Any process that stops, prevents or reduces the frequency, rate or extent of reverse transcription.	tmpzr1t_l9r_go_relaxed.owl	inhibition of reverse transcription|downregulation of reverse transcription|down-regulation of reverse transcription|down regulation of reverse transcription							tb	2012-04-03T11:13:35Z					biological_process											owl:Class	
GO:0002824	biolink:NamedThing	positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	Any process that activates or increases the frequency, rate, or extent of an adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains. An example of this process is found in the Gnathostomata.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1905750	biolink:NamedThing	negative regulation of endosome to plasma membrane protein transport	Any process that stops, prevents or reduces the frequency, rate or extent of endosome to plasma membrane protein transport.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of endosome to plasma membrane protein transport|inhibition of endosome to plasma membrane protein transport|downregulation of endosome to plasma membrane protein transport|down regulation of endosome to plasma membrane protein transport							pga	2016-12-09T13:46:21Z					biological_process											owl:Class	
GO:1903077	biolink:NamedThing	negative regulation of protein localization to plasma membrane	Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to plasma membrane.	tmpzr1t_l9r_go_relaxed.owl	down regulation of protein localization in plasma membrane|inhibition of protein targeting to plasma membrane|negative regulation of protein-plasma membrane targeting|inhibition of protein localisation in plasma membrane|down regulation of protein-plasma membrane targeting|downregulation of protein localization in plasma membrane|down-regulation of protein targeting to plasma membrane|downregulation of protein targeting to plasma membrane|down regulation of protein localisation in plasma membrane|downregulation of protein localization to plasma membrane|negative regulation of establishment of protein localisation in plasma membrane|down regulation of protein localization to plasma membrane|down regulation of protein targeting to plasma membrane|down-regulation of protein-plasma membrane targeting|negative regulation of protein localisation in plasma membrane|negative regulation of establishment of protein localization in plasma membrane|downregulation of protein-plasma membrane targeting|inhibition of protein localization to plasma membrane|down-regulation of protein localization in plasma membrane|negative regulation of protein localization in plasma membrane|inhibition of protein-plasma membrane targeting|downregulation of protein localisation in plasma membrane|inhibition of protein localization in plasma membrane|down-regulation of protein localisation in plasma membrane|negative regulation of establishment of protein localization to plasma membrane|down-regulation of protein localization to plasma membrane|negative regulation of protein targeting to plasma membrane							tb	2014-05-29T17:10:16Z			GO:1905964|GO:0090005		biological_process											owl:Class	
GO:0070471	biolink:NamedThing	uterine smooth muscle contraction	A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the uterus. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The uterus is a muscular organ of the female mammal for containing and usually for nourishing the young during development prior to birth.	tmpzr1t_l9r_go_relaxed.owl	myometrial smooth muscle contraction|myometrium contraction|myometrial contraction													biological_process											owl:Class	
GO:0006939	biolink:NamedThing	smooth muscle contraction	A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. Smooth muscle differs from striated muscle in the much higher actin/myosin ratio, the absence of conspicuous sarcomeres and the ability to contract to a much smaller fraction of its resting length.	tmpzr1t_l9r_go_relaxed.owl	visceral muscle contraction													biological_process											owl:Class	
GO:0001892	biolink:NamedThing	embryonic placenta development	The embryonically driven process whose specific outcome is the progression of the placenta over time, from its formation to the mature structure. The placenta is an organ of metabolic interchange between fetus and mother, partly of embryonic origin and partly of maternal origin.	tmpzr1t_l9r_go_relaxed.owl	fetal placenta development													biological_process											owl:Class	
GO:0090709	biolink:NamedThing	regulation of timing of plant organ formation	Any process that modulates the rate, frequency or extent of plant organ formation at a consistent predetermined time point during development.	tmpzr1t_l9r_go_relaxed.owl								tb	2016-10-05T12:49:58Z					biological_process											owl:Class	
GO:1905428	biolink:NamedThing	regulation of plant organ formation	Any process that modulates the frequency, rate or extent of plant organ formation.	tmpzr1t_l9r_go_relaxed.owl								tb	2016-09-07T18:57:47Z					biological_process											owl:Class	
GO:0048530	biolink:NamedThing	fruit morphogenesis	The process in which the anatomical structures of a fruit are generated and organized. A fruit is a reproductive body of a seed plant.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0090698	biolink:NamedThing	post-embryonic plant morphogenesis	The process, occurring after plant embryonic development, by which anatomical structures are generated and organized.	tmpzr1t_l9r_go_relaxed.owl								tb	2016-08-25T17:08:33Z					biological_process											owl:Class	
GO:0000335	biolink:NamedThing	negative regulation of transposition, DNA-mediated	Any process that stops, prevents, or reduces the frequency, rate or extent of DNA transposition.	tmpzr1t_l9r_go_relaxed.owl	down regulation of DNA transposition|downregulation of DNA transposition|negative regulation of DNA transposition|down-regulation of DNA transposition|inhibition of DNA transposition													biological_process											owl:Class	
GO:1900933	biolink:NamedThing	negative regulation of nonadec-1-ene metabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of nonadec-1-ene metabolic process.	tmpzr1t_l9r_go_relaxed.owl	inhibition of nonadec-1-ene metabolic process|down-regulation of nonadec-1-ene metabolic process|down regulation of nonadec-1-ene metabolic process|negative regulation of nonadec-1-ene metabolism|down regulation of nonadec-1-ene metabolism|inhibition of nonadec-1-ene metabolism|downregulation of nonadec-1-ene metabolic process|down-regulation of nonadec-1-ene metabolism|downregulation of nonadec-1-ene metabolism							tt	2012-06-14T03:11:50Z					biological_process											owl:Class	
GO:2000674	biolink:NamedThing	regulation of type B pancreatic cell apoptotic process	Any process that modulates the frequency, rate or extent of type B pancreatic cell apoptotic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of pancreatic beta cell apoptosis|regulation of type B pancreatic cell apoptosis|regulation of pancreatic B cell apoptosis							pr	2011-05-09T11:51:09Z					biological_process											owl:Class	
GO:0019532	biolink:NamedThing	oxalate transport	The directed movement of oxalate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Oxalate, or ethanedioic acid, occurs in many plants and is highly toxic to animals.	tmpzr1t_l9r_go_relaxed.owl	oxalic acid transport|ethanedioate transport|ethanedioic acid transport													biological_process											owl:Class	
GO:1901036	biolink:NamedThing	positive regulation of L-glutamine import across plasma membrane	Any process that activates or increases the frequency, rate or extent of L-glutamine import into cell.	tmpzr1t_l9r_go_relaxed.owl	up regulation of L-glutamine uptake|up-regulation of L-glutamine import|upregulation of L-glutamine import|activation of L-glutamine import|positive regulation of L-glutamine import|positive regulation of L-glutamine uptake|activation of L-glutamine uptake|up-regulation of L-glutamine uptake|up regulation of L-glutamine import|upregulation of L-glutamine uptake							al	2012-06-21T07:31:56Z					biological_process											owl:Class	
GO:1900584	biolink:NamedThing	o-orsellinic acid biosynthetic process	The chemical reactions and pathways resulting in the formation of o-orsellinic acid.	tmpzr1t_l9r_go_relaxed.owl	o-orsellinic acid anabolism|o-orsellinic acid formation|o-orsellinic acid biosynthesis|o-orsellinic acid synthesis							di	2012-05-15T06:48:11Z					biological_process											owl:Class	
GO:1900582	biolink:NamedThing	o-orsellinic acid metabolic process	The chemical reactions and pathways involving o-orsellinic acid.	tmpzr1t_l9r_go_relaxed.owl	o-orsellinic acid metabolism							di	2012-05-15T06:47:42Z					biological_process											owl:Class	
GO:1902415	biolink:NamedThing	regulation of mRNA binding	Any process that modulates the frequency, rate or extent of mRNA binding.	tmpzr1t_l9r_go_relaxed.owl								rb	2013-09-13T18:57:15Z					biological_process											owl:Class	
GO:0043960	biolink:NamedThing	L-erythro-3-methylmalyl-CoA dehydratase activity	Catalysis of the reaction: L-erythro-3-methylmalyl-CoA = mesaconyl-CoA + H2O.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0070016	biolink:NamedThing	armadillo repeat domain binding	Binding to an armadillo repeat domain, an approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity protein armadillo. Arm-repeat proteins are involved in various processes, including intracellular signalling and cytoskeletal regulation.	tmpzr1t_l9r_go_relaxed.owl	Arm repeat domain binding|armadillo domain binding|armadillo repeat binding													molecular_function											owl:Class	
GO:0047992	biolink:NamedThing	hydroxylysine kinase activity	Catalysis of the reaction: erythro-5-hydroxy-L-lysine + GTP = 5-phosphonooxy-L-lysine + GDP + 2 H(+).	tmpzr1t_l9r_go_relaxed.owl	GTP:5-hydroxy-L-lysine O-phosphotransferase activity|hydroxylysine kinase (phosphorylating)|guanosine triphosphate:5-hydroxy-L-lysine O-phosphotransferase activity				RHEA:19049|MetaCyc:HYDROXYLYSINE-KINASE-RXN|Reactome:R-HSA-6788611|KEGG_REACTION:R03378|EC:2.7.1.81									molecular_function											owl:Class	
GO:0045219	biolink:NamedThing	regulation of FasL production	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of FasL.	tmpzr1t_l9r_go_relaxed.owl	regulation of FasL anabolism|regulation of FasL biosynthesis|regulation of FasL synthesis|regulation of FasL formation													biological_process											owl:Class	
GO:0034721	biolink:NamedThing	histone H3-K4 demethylation, trimethyl-H3-K4-specific	The modification of histone H3 by the removal of a methyl group from a trimetylated lysine at position 4 of the histone.	tmpzr1t_l9r_go_relaxed.owl	histone H3-K4 tridemethylation|H3K4 demethylation (me3)													biological_process											owl:Class	
GO:0034720	biolink:NamedThing	histone H3-K4 demethylation	The modification of histone H3 by the removal of a methyl group from lysine at position 4 of the histone.	tmpzr1t_l9r_go_relaxed.owl	H3K4 demethylation (me1 me2 and me3)													biological_process											owl:Class	
GO:0015953	biolink:NamedThing	pyrimidine nucleotide interconversion	The chemical reactions and pathways by which a pyrimidine nucleotide is synthesized from another pyrimidine nucleotide.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0006220	biolink:NamedThing	pyrimidine nucleotide metabolic process	The chemical reactions and pathways involving a pyrimidine nucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.	tmpzr1t_l9r_go_relaxed.owl	pyrimidine metabolism|pyrimidine nucleotide metabolism|pyrimidine metabolic process													biological_process											owl:Class	
GO:1901939	biolink:NamedThing	(-)-exo-alpha-bergamotene catabolic process	The chemical reactions and pathways resulting in the breakdown of (-)-exo-alpha-bergamotene.	tmpzr1t_l9r_go_relaxed.owl	(-)-exo-alpha-bergamotene catabolism|(-)-exo-alpha-bergamotene degradation|(-)-exo-alpha-bergamotene breakdown							ms	2013-02-18T14:55:27Z					biological_process											owl:Class	
GO:1901984	biolink:NamedThing	negative regulation of protein acetylation	Any process that stops, prevents or reduces the frequency, rate or extent of protein acetylation.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of protein amino acid acetylation|downregulation of protein amino acid acetylation|negative regulation of protein amino acid acetylation|down-regulation of protein acetylation|downregulation of protein acetylation|inhibition of protein amino acid acetylation|inhibition of protein acetylation|down regulation of protein acetylation|down regulation of protein amino acid acetylation							ss	2013-03-14T00:40:11Z					biological_process											owl:Class	
GO:1905423	biolink:NamedThing	positive regulation of plant organ morphogenesis	Any process that activates or increases the frequency, rate or extent of plant organ morphogenesis.	tmpzr1t_l9r_go_relaxed.owl	activation of plant organ morphogenesis|upregulation of plant organ morphogenesis|up-regulation of plant organ morphogenesis|up regulation of plant organ morphogenesis							tb	2016-09-06T23:00:29Z					biological_process											owl:Class	
GO:2001156	biolink:NamedThing	regulation of proline catabolic process to glutamate	Any process that modulates the frequency, rate or extent of proline catabolic process to glutamate.	tmpzr1t_l9r_go_relaxed.owl	regulation of proline degradation to glutamate|regulation of proline oxidation|regulation of proline breakdown to glutamate							mcc	2011-10-25T08:54:37Z					biological_process											owl:Class	
GO:2000214	biolink:NamedThing	regulation of proline metabolic process	Any process that modulates the frequency, rate or extent of proline metabolic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of proline metabolism							mah	2010-11-03T02:45:20Z					biological_process											owl:Class	
GO:2000811	biolink:NamedThing	negative regulation of anoikis	Any process that stops, prevents or reduces the frequency, rate or extent of anoikis.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of suspension induced apoptosis|negative regulation of detachment induced cell death							pr	2011-07-07T09:42:20Z					biological_process											owl:Class	
GO:0071934	biolink:NamedThing	thiamine transmembrane transport	The process in which thiamine is transported across a membrane. Thiamine is vitamin B1, a water soluble vitamin present in fresh vegetables and meats, especially liver.	tmpzr1t_l9r_go_relaxed.owl	thiamin transmembrane transport|vitamin B1 transmembrane transport|thiamine membrane transport					Note that this term is not intended for use in annotating lateral movement within membranes.		mah	2010-09-29T02:59:39Z					biological_process											owl:Class	
GO:1905857	biolink:NamedThing	positive regulation of pentose-phosphate shunt	Any process that activates or increases the frequency, rate or extent of pentose-phosphate shunt.	tmpzr1t_l9r_go_relaxed.owl								vw	2017-01-23T14:00:26Z					biological_process											owl:Class	
GO:0031336	biolink:NamedThing	negative regulation of sulfur amino acid metabolic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving sulfur amino acids.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of sulfur amino acid metabolism|down-regulation of sulfur amino acid metabolic process|downregulation of sulfur amino acid metabolic process|inhibition of sulfur amino acid metabolic process|down regulation of sulfur amino acid metabolic process													biological_process											owl:Class	
GO:0070968	biolink:NamedThing	pyrroloquinoline quinone binding	Binding to pyrroloquinoline quinone, PQQ, the coenzyme or the prosthetic group of certain alcohol dehydrogenases and glucose dehydrogenases.	tmpzr1t_l9r_go_relaxed.owl	PQQ binding							mah	2009-10-02T11:39:13Z					molecular_function											owl:Class	
GO:0050736	biolink:NamedThing	O-malonyltransferase activity	Catalysis of the transfer of a malonyl group to an oxygen atom on the acceptor molecule.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0016420	biolink:NamedThing	malonyltransferase activity	Catalysis of the transfer of a malonyl (HOOC-CH2-CO-) group to an acceptor molecule.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0102003	biolink:NamedThing	Delta8-sphingolipid desaturase activity	Catalysis of the reaction: phytosphingosine(1+) + O2 + a reduced electron acceptor <=> 4-hydroxy-trans-8-sphingenine + 2 H2O + an oxidized electron acceptor.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:1.14.19.4-RXN|EC:1.14.19.4									molecular_function											owl:Class	
GO:0052631	biolink:NamedThing	sphingolipid delta-8 desaturase activity	Catalysis of the formation of a double bond between C8 and C9 of the long chain base of a sphingolipid. For example, sphinganine (d18:0) = 8-sphingenine (d18:1delta8); phytosphinganine (t18:0) = 8-phytosphingenine (t18:1delta8); and 4-sphingenine (18:1delta4) = 4,8-sphingadienine (d18:2delta4,8).	tmpzr1t_l9r_go_relaxed.owl					RHEA:46268|MetaCyc:RXN-7798									molecular_function											owl:Class	
GO:0006706	biolink:NamedThing	steroid catabolic process	The chemical reactions and pathways resulting in the breakdown of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus.	tmpzr1t_l9r_go_relaxed.owl	steroid degradation|steroid breakdown|steroid catabolism													biological_process											owl:Class	
GO:0045594	biolink:NamedThing	positive regulation of cumulus cell differentiation	Any process that activates or increases the frequency, rate or extent of ovarian cumulus cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	activation of cumulus cell differentiation|stimulation of cumulus cell differentiation|positive regulation of ovarian cumulus cell differentiation|upregulation of cumulus cell differentiation|up regulation of cumulus cell differentiation|up-regulation of cumulus cell differentiation													biological_process											owl:Class	
GO:0045592	biolink:NamedThing	regulation of cumulus cell differentiation	Any process that modulates the frequency, rate or extent of ovarian cumulus cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	regulation of ovarian cumulus cell differentiation													biological_process											owl:Class	
GO:0046804	biolink:NamedThing	peptide cross-linking via (2S,3S,4Xi,6R)-3-methyl-lanthionine sulfoxide	The formation of a protein-protein cross-link between peptidyl-threonine and peptidyl-cysteine by the synthesis of (2S,3S,4Xi,6R)-3-methyl-lanthionine sulfoxide (3-methyl-L-lanthionine sulfoxide), as found in the antibiotic actagardine.	tmpzr1t_l9r_go_relaxed.owl	peptide cross-linking via (2S,3S,4Xi,6R)-3-methyl-lanthionine sulphoxide				RESID:AA0330									biological_process											owl:Class	
GO:0032297	biolink:NamedThing	negative regulation of DNA-dependent DNA replication initiation	Any process that stops, prevents, or reduces the frequency, rate or extent of initiation of DNA-dependent DNA replication.	tmpzr1t_l9r_go_relaxed.owl	downregulation of DNA replication initiation|negative regulation of DNA replication initiation|inhibition of DNA replication initiation|down regulation of DNA replication initiation|down-regulation of DNA replication initiation													biological_process											owl:Class	
GO:0102290	biolink:NamedThing	beta-amyrin monooxygenase activity	Catalysis of the reaction: beta-amyrin + O2 + NADPH + H+ <=> 11alpha-hydroxy-beta-amyrin + H2O + NADP.	tmpzr1t_l9r_go_relaxed.owl					EC:1.14.14.152|RHEA:31715|MetaCyc:RXN-12681									molecular_function											owl:Class	
GO:0033602	biolink:NamedThing	negative regulation of dopamine secretion	Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of dopamine.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of dopamine secretion|downregulation of dopamine secretion|down regulation of dopamine secretion|inhibition of dopamine secretion													biological_process											owl:Class	
GO:0010605	biolink:NamedThing	negative regulation of macromolecule metabolic process	Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1902749	biolink:NamedThing	regulation of cell cycle G2/M phase transition	Any signalling pathway that modulates the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to M phase of the cell cycle.	tmpzr1t_l9r_go_relaxed.owl								jl	2014-03-05T15:38:15Z					biological_process											owl:Class	
GO:1901987	biolink:NamedThing	regulation of cell cycle phase transition	Any process that modulates the frequency, rate or extent of cell cycle phase transition.	tmpzr1t_l9r_go_relaxed.owl	cell cycle control|regulation of cell cycle transition							jl	2013-03-19T16:11:27Z					biological_process											owl:Class	
GO:0071579	biolink:NamedThing	regulation of zinc ion transport	Any process that modulates the frequency, rate or extent of the directed movement of zinc ions (Zn2+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-01-28T03:02:15Z					biological_process											owl:Class	
GO:0060310	biolink:NamedThing	regulation of elastin catabolic process	Any process that modulates the rate, frequency or extent of elastin catabolism, the chemical reactions and pathways resulting in the breakdown of elastin.	tmpzr1t_l9r_go_relaxed.owl	regulation of elastin catabolism|regulation of elastin degradation|regulation of elastin breakdown													biological_process											owl:Class	
GO:1903081	biolink:NamedThing	negative regulation of C-C chemokine receptor CCR7 signaling pathway	Any process that stops, prevents or reduces the frequency, rate or extent of C-C chemokine receptor CCR7 signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of CCR7 signaling pathway|negative regulation of C-C chemokine receptor CCR7 signalling pathway|inhibition of C-C chemokine receptor CCR7 signaling pathway|down-regulation of C-C chemokine receptor CCR7 signalling pathway|down regulation of CCR7 signaling pathway|negative regulation of CCR7 signaling pathway|down regulation of C-C chemokine receptor CCR7 signalling pathway|down regulation of C-C chemokine receptor CCR7 signaling pathway|down-regulation of C-C chemokine receptor CCR7 signaling pathway|downregulation of C-C chemokine receptor CCR7 signalling pathway|downregulation of C-C chemokine receptor CCR7 signaling pathway|inhibition of C-C chemokine receptor CCR7 signalling pathway|inhibition of CCR7 signaling pathway|downregulation of CCR7 signaling pathway							rl	2014-05-29T18:32:55Z					biological_process											owl:Class	
GO:0070100	biolink:NamedThing	negative regulation of chemokine-mediated signaling pathway	Any process that decreases the rate, frequency or extent of the series of molecular events generated as a consequence of a chemokine binding to a cell surface receptor.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of chemokine-mediated signalling pathway													biological_process											owl:Class	
GO:0032219	biolink:NamedThing	cell wall macromolecule catabolic process involved in cytogamy	The chemical reactions and pathways resulting in the breakdown of macromolecules forming part of a cell wall that contribute to cytogamy.	tmpzr1t_l9r_go_relaxed.owl	cell wall macromolecule catabolic process during cytogamy													biological_process											owl:Class	
GO:0102905	biolink:NamedThing	valencene synthase activity	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate(3-) <=> (+)-valencene + diphosphoric acid.	tmpzr1t_l9r_go_relaxed.owl					RHEA:29511|EC:4.2.3.73|MetaCyc:RXN-8608									molecular_function											owl:Class	
GO:0075197	biolink:NamedThing	haustorium neck formation	The assembly by the symbiont of a neck-like structure for the purpose of penetration into its host organism. The neck-like structure connects haustorium mother cell and haustorium. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	symbiont haustorium neck formation for entry into host|formation of symbiont haustorium neck for entry into host	https://github.com/geneontology/go-ontology/issues/18557				Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products from the symbiont involved in this process.								biological_process											owl:Class	
GO:0035019	biolink:NamedThing	somatic stem cell population maintenance	Any process by which an organism retains a population of somatic stem cells, undifferentiated cells in the embryo or adult which can undergo unlimited division and give rise to cell types of the body other than those of the germ-line.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0050431	biolink:NamedThing	transforming growth factor beta binding	Binding to TGF-beta, transforming growth factor beta, a multifunctional peptide that controls proliferation, differentiation and other functions in many cell types.	tmpzr1t_l9r_go_relaxed.owl	TGFbeta binding|transforming growth factor beta ligand binding to type I receptor|transforming growth factor beta ligand binding to type II receptor|TGF-beta binding													molecular_function											owl:Class	
GO:0062152	biolink:NamedThing	mRNA (cytidine-5-)-methyltransferase activity	Catalysis of the reaction: a cytidine in mRNA + S-adenosyl-L-methionine = a 5-methylcytidine in mRNA + H(+) + S-adenosyl-L-homocysteine.	tmpzr1t_l9r_go_relaxed.owl	mRNA (cytosine-5-)-methyltransferase activity				RHEA:61464			dph	2019-09-18T14:40:32Z					molecular_function											owl:Class	
GO:0008174	biolink:NamedThing	mRNA methyltransferase activity	Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a nucleoside residue in an mRNA molecule.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0090567	biolink:NamedThing	reproductive shoot system development	The process whose specific outcome is the progression of a reproductive shoot system over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl								tb	2014-04-25T15:42:03Z					biological_process											owl:Class	
GO:0032973	biolink:NamedThing	amino acid export across plasma membrane	The directed movement of amino acids from inside of a cell, across the plasma membrane and into the extracellular region.	tmpzr1t_l9r_go_relaxed.owl	amino acid export|amino acid efflux|amino acid transmembrane export							jl	2012-11-14T14:27:40Z			GO:0044746		biological_process											owl:Class	
GO:0034180	biolink:NamedThing	negative regulation of toll-like receptor 13 signaling pathway	Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 13 signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of toll-like receptor 13 signalling pathway|negative regulation of TLR13 signaling pathway													biological_process											owl:Class	
GO:1905226	biolink:NamedThing	regulation of adhesion of symbiont to host epithelial cell	Any process that modulates the frequency, rate or extent of adhesion of symbiont to host epithelial cell.	tmpzr1t_l9r_go_relaxed.owl								pga	2016-06-07T13:15:08Z					biological_process											owl:Class	
GO:0071338	biolink:NamedThing	positive regulation of hair follicle cell proliferation	Any process that activates or increases the rate or extent of hair follicle cell proliferation.	tmpzr1t_l9r_go_relaxed.owl	upregulation of hair follicle cell proliferation|stimulation of hair follicle cell proliferation|activation of hair follicle cell proliferation|up regulation of hair follicle cell proliferation|up-regulation of hair follicle cell proliferation							mah	2009-12-11T11:00:57Z					biological_process											owl:Class	
GO:0071336	biolink:NamedThing	regulation of hair follicle cell proliferation	Any process that modulates the frequency, rate or extent of hair follicle cell proliferation.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-12-11T10:53:40Z					biological_process											owl:Class	
GO:0032000	biolink:NamedThing	positive regulation of fatty acid beta-oxidation	Any process that activates or increases the frequency, rate or extent of fatty acid beta-oxidation.	tmpzr1t_l9r_go_relaxed.owl	activation of fatty acid beta-oxidation|up-regulation of fatty acid beta-oxidation|up regulation of fatty acid beta-oxidation|stimulation of fatty acid beta-oxidation|upregulation of fatty acid beta-oxidation													biological_process											owl:Class	
GO:0046321	biolink:NamedThing	positive regulation of fatty acid oxidation	Any process that activates or increases the frequency, rate or extent of fatty acid oxidation.	tmpzr1t_l9r_go_relaxed.owl	up regulation of fatty acid oxidation|upregulation of fatty acid oxidation|activation of fatty acid oxidation|up-regulation of fatty acid oxidation|stimulation of fatty acid oxidation													biological_process											owl:Class	
GO:0009728	biolink:NamedThing	detection of gibberellic acid stimulus	The series of events in which a gibberellic acid stimulus is received by a cell and converted into a molecular signal.	tmpzr1t_l9r_go_relaxed.owl	perception of gibberellic acid stimulus													biological_process											owl:Class	
GO:0009739	biolink:NamedThing	response to gibberellin	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gibberellin stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to gibberellin stimulus|response to gibberellic acid stimulus													biological_process											owl:Class	
GO:1904303	biolink:NamedThing	positive regulation of maternal process involved in parturition	Any process that activates or increases the frequency, rate or extent of maternal process involved in parturition.	tmpzr1t_l9r_go_relaxed.owl	activation of maternal process involved in parturition|upregulation of maternal process involved in parturition|up regulation of maternal process involved in parturition|up-regulation of maternal process involved in parturition							sl	2015-06-09T23:01:45Z					biological_process											owl:Class	
GO:1904301	biolink:NamedThing	regulation of maternal process involved in parturition	Any process that modulates the frequency, rate or extent of maternal process involved in parturition.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-06-09T23:01:32Z					biological_process											owl:Class	
GO:0072222	biolink:NamedThing	metanephric early distal convoluted tubule development	The process whose specific outcome is the progression of the metanephric early distal convoluted tubule over time, from its formation to the mature structure. The metanephric early distal convoluted tubule contains metanephric DCT cells and is vasopressin-insensitive.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-03-18T03:35:46Z					biological_process											owl:Class	
GO:0072243	biolink:NamedThing	metanephric nephron epithelium development	The process whose specific outcome is the progression of the metanephric nephron epithelium over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. The metanephric nephron epithelium is a tissue that covers the surface of a nephron in the metanephros.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-03-19T03:29:49Z					biological_process											owl:Class	
GO:0042353	biolink:NamedThing	fucose biosynthetic process	The chemical reactions and pathways resulting in the formation of fucose (6-deoxygalactose).	tmpzr1t_l9r_go_relaxed.owl	fucose formation|fucose synthesis|fucose anabolism|fucose biosynthesis													biological_process											owl:Class	
GO:0000087	biolink:NamedThing	mitotic M phase	A cell cycle phase during which nuclear division occurs, and which is comprises the phases: prophase, metaphase, anaphase and telophase and occurs as part of a mitotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl	M phase of mitotic cell cycle|M-phase of mitotic cell cycle					Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).								biological_process											owl:Class	
GO:0000279	biolink:NamedThing	M phase	A cell cycle phase during which nuclear division occurs, and which is comprises the phases: prophase, metaphase, anaphase and telophase.	tmpzr1t_l9r_go_relaxed.owl	M-phase				Wikipedia:M_phase	Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).								biological_process											owl:Class	
GO:0140196	biolink:NamedThing	positive regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process	Any process that activates or increases the frequency, rate or extent of an adenylate cyclase-activating adrenergic receptor signaling pathway involved in some heart process.	tmpzr1t_l9r_go_relaxed.owl								pg	2018-02-15T19:13:29Z					biological_process											owl:Class	
GO:0099185	biolink:NamedThing	postsynaptic intermediate filament cytoskeleton organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of  cytoskeletal structures comprised of intermediate filament and their associated proteins in the postsynaptic cytoskeleton.	tmpzr1t_l9r_go_relaxed.owl								dos	2017-12-20T13:47:30Z					biological_process											owl:Class	
GO:0045104	biolink:NamedThing	intermediate filament cytoskeleton organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising intermediate filaments and their associated proteins.	tmpzr1t_l9r_go_relaxed.owl	intermediate filament cytoskeleton organization and biogenesis|intermediate filament cytoskeleton organisation													biological_process											owl:Class	
GO:0007535	biolink:NamedThing	donor selection	The process that determines which donor locus a cell uses, in preference to another, in mating type switching.	tmpzr1t_l9r_go_relaxed.owl	donor preference													biological_process											owl:Class	
GO:0045339	biolink:NamedThing	farnesyl diphosphate catabolic process	The chemical reactions and pathways resulting in the breakdown of farnesyl diphosphate.	tmpzr1t_l9r_go_relaxed.owl	farnesyl diphosphate degradation|farnesyl diphosphate breakdown|farnesyl diphosphate catabolism													biological_process											owl:Class	
GO:0016115	biolink:NamedThing	terpenoid catabolic process	The chemical reactions and pathways resulting in the breakdown of terpenoids, any member of a class of compounds characterized by an isoprenoid chemical structure.	tmpzr1t_l9r_go_relaxed.owl	terpenoid degradation|terpenoid breakdown|terpenoid catabolism													biological_process											owl:Class	
GO:0045862	biolink:NamedThing	positive regulation of proteolysis	Any process that activates or increases the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein.	tmpzr1t_l9r_go_relaxed.owl	up regulation of proteolysis|activation of proteolysis|up-regulation of proteolysis|stimulation of proteolysis|upregulation of proteolysis|positive regulation of peptidolysis													biological_process											owl:Class	
GO:0150024	biolink:NamedThing	oxidised low-density lipoprotein particle clearance	The process in which an oxidised low-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.	tmpzr1t_l9r_go_relaxed.owl	ox-LDL particle clearance|oxidized LDL particle clearance|oxLDL particle clearance|oxidized low-density lipoprotein particle clearance|oxidised LDL particle clearance							bc	2018-02-05T16:14:05Z					biological_process											owl:Class	
GO:1903114	biolink:NamedThing	silver ion transmembrane transporter complex	A protein complex which is capable of silver ion transmembrane transporter activity.	tmpzr1t_l9r_go_relaxed.owl						An example of this is CusA in E. coli (UniProt symbol P38054) in PMID:11283292 (inferred from direct assay).		bhm	2014-06-10T10:00:02Z					cellular_component											owl:Class	
GO:0015973	biolink:NamedThing	guanosine pentaphosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of guanine pentaphosphate (5'-pppGpp-3'), a derivative of guanine riboside with five phosphates.	tmpzr1t_l9r_go_relaxed.owl	guanosine pentaphosphate formation|guanosine pentaphosphate anabolism|guanosine pentaphosphate biosynthesis|guanosine pentaphosphate (5'-pppGpp-3') biosynthesis|guanosine pentaphosphate synthesis|guanosine pentaphosphate (5'-pppGpp-3') biosynthetic process													biological_process											owl:Class	
GO:0034036	biolink:NamedThing	purine ribonucleoside bisphosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of a purine ribonucleoside bisphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar.	tmpzr1t_l9r_go_relaxed.owl	purine ribonucleoside bisphosphate formation|purine ribonucleoside bisphosphate synthesis|purine ribonucleoside bisphosphate anabolism|purine ribonucleoside bisphosphate biosynthesis													biological_process											owl:Class	
GO:0102363	biolink:NamedThing	isoscopoletin-O-methyltransferase activity	Catalysis of the reaction: isoscopoletin + S-adenosyl-L-methionine  <=> scoparone + S-adenosyl-L-homocysteine  + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-13475									molecular_function											owl:Class	
GO:1904698	biolink:NamedThing	negative regulation of acinar cell proliferation	Any process that stops, prevents or reduces the frequency, rate or extent of acinar cell proliferation.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of acinic cell proliferation|down regulation of acinar cell proliferation|negative regulation of acinous cell proliferation|downregulation of acinous cell proliferation|downregulation of acinar cell proliferation|negative regulation of acinic cell proliferation|down-regulation of acinar cell proliferation|downregulation of acinic cell proliferation|inhibition of acinic cell proliferation|down regulation of acinic cell proliferation|down-regulation of acinous cell proliferation|inhibition of acinous cell proliferation|inhibition of acinar cell proliferation|down regulation of acinous cell proliferation							sl	2015-09-30T15:19:57Z					biological_process											owl:Class	
GO:0060213	biolink:NamedThing	positive regulation of nuclear-transcribed mRNA poly(A) tail shortening	Any process that increases the frequency, rate or extent of poly(A) tail shortening of a nuclear-transcribed mRNA. Poly(A) tail shortening is the decrease in length of the poly(A) tail of an mRNA from full length to an oligo(A) length.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of mRNA deadenylation|positive regulation of nuclear mRNA poly(A) tail shortening|positive regulation of 3' to 5' mRNA deadenylation													biological_process											owl:Class	
GO:0102375	biolink:NamedThing	11-oxo-beta-amyrin 30-oxidase activity	Catalysis of the reaction: 11-oxo-beta-amyrin + 3 NADPH + 3 O2 + 2 H+ <=> glycyrrhetinic acid + 3 NADP + 4 H2O.	tmpzr1t_l9r_go_relaxed.owl					EC:1.14.14.115|RHEA:35499|MetaCyc:RXN-13506									molecular_function											owl:Class	
GO:0070174	biolink:NamedThing	negative regulation of enamel mineralization	Any process that stops, prevents, or reduces the frequency, rate or extent of enamel mineralization, the deposition of calcium salts in tooth enamel.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0070173	biolink:NamedThing	regulation of enamel mineralization	Any process that modulates the frequency, rate or extent of enamel mineralization, the deposition of calcium salts in tooth enamel.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0003261	biolink:NamedThing	cardiac muscle progenitor cell migration to the midline involved in heart field formation	The orderly movement of a myocardial progenitor cell toward the midline to form the heart field. Cardiac muscle progenitor cells are non-terminally differentiated, mesoderm-derived cells that are committed to differentiate into myocardial cells of the heart.	tmpzr1t_l9r_go_relaxed.owl	myocardial progenitor cell midline convergence							dph	2009-10-15T01:57:55Z					biological_process											owl:Class	
GO:0060975	biolink:NamedThing	cardioblast migration to the midline involved in heart field formation	The orderly movement of a cardioblast toward the midline to form the heart field. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.	tmpzr1t_l9r_go_relaxed.owl	cardioblast midline convergence|cardiac progenitor cell midline migration							dph	2009-10-06T10:59:36Z					biological_process											owl:Class	
GO:0035848	biolink:NamedThing	oviduct morphogenesis	The process in which anatomical structures of the oviduct are generated and organized. An oviduct is a tube through which an ova passes from the ovary to the uterus, or from the ovary to the outside of the organism.	tmpzr1t_l9r_go_relaxed.owl	fallopian tube morphogenesis							bf	2011-05-10T11:01:20Z					biological_process											owl:Class	
GO:0043314	biolink:NamedThing	negative regulation of neutrophil degranulation	Any process that stops, prevents, or reduces the rate of neutrophil degranulation.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of neutrophil granule exocytosis|down-regulation of neutrophil degranulation|inhibition of neutrophil degranulation|downregulation of neutrophil degranulation|down regulation of neutrophil degranulation													biological_process											owl:Class	
GO:0044831	biolink:NamedThing	modulation by virus of host cytokine production	Any process in which a virus modulates the frequency, rate or extent of cytokine production in its host organism.	tmpzr1t_l9r_go_relaxed.owl								jl	2014-02-06T12:49:02Z					biological_process											owl:Class	
GO:0072596	biolink:NamedThing	establishment of protein localization to chloroplast	The directed movement of a protein to a specific location in a chloroplast.	tmpzr1t_l9r_go_relaxed.owl	establishment of protein localisation to chloroplast							mah	2011-02-14T02:16:13Z					biological_process											owl:Class	
GO:0072598	biolink:NamedThing	protein localization to chloroplast	A process in which a protein is transported to, or maintained at, a location in a chloroplast.	tmpzr1t_l9r_go_relaxed.owl	protein localisation to chloroplast							mah	2011-02-14T02:20:30Z					biological_process											owl:Class	
GO:0018155	biolink:NamedThing	peptide cross-linking via sn-(2S,6R)-lanthionine	The formation of a protein-protein cross-link between peptidyl-serine and peptidyl-cysteine by the synthesis of sn-(2S,6R)-lanthionine (meso-lanthione).	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0111									biological_process											owl:Class	
GO:0018081	biolink:NamedThing	peptide cross-linking via lanthionine or 3-methyl-lanthionine	The synthesis of (2R,6R)-lanthionine, sn-(2S,6R)-lanthionine or (2S,3S,6R)-3-methyl-lanthionine, forming an intra-polypeptide cross-link between peptidyl-cysteine, and peptidyl-serine or peptidyl-threonine; dehydration of the serine or threonine residue to the alpha,beta-unsaturated amino acid is the first step; a bond then forms between the ethylene (ethene) group thus formed and the sulfur atom of a cysteine, with the inversion of the configuration of the alpha carbon of the serine or threonine occurring during the process.	tmpzr1t_l9r_go_relaxed.owl	peptide cross-linking via the thioethers lanthionine or 3-methyl-lanthionine|peptide cross-linking via the thiolethers lanthionine or 3-methyl-lanthionine				RESID:AA0111|RESID:AA0112|RESID:AA0110									biological_process											owl:Class	
GO:0060701	biolink:NamedThing	negative regulation of ribonuclease activity	Any process that decreases the rate, frequency, or extent of ribonuclease activity, catalysis of the hydrolysis of phosphodiester bonds in chains of RNA.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-06-08T02:49:46Z					biological_process											owl:Class	
GO:0051158	biolink:NamedThing	L-arabitol catabolic process	The chemical reactions and pathways resulting in the breakdown of L-arabitol, the pentitol derived from arabinose or lyxose by reduction of the aldehyde group.	tmpzr1t_l9r_go_relaxed.owl	L-arabitol breakdown|L-arabitol catabolism|L-arabitol degradation													biological_process											owl:Class	
GO:0051157	biolink:NamedThing	arabitol catabolic process	The chemical reactions and pathways resulting in the breakdown of arabitol, the pentitol derived from arabinose or lyxose by reduction of the aldehyde group.	tmpzr1t_l9r_go_relaxed.owl	arabitol degradation|arabitol utilization|arabitol catabolism|arabitol breakdown											GO:0019591		biological_process											owl:Class	
GO:0033683	biolink:NamedThing	nucleotide-excision repair, DNA incision	A process that results in the endonucleolytic cleavage of the damaged strand of DNA. The incision occurs at the junction of single-stranded DNA and double-stranded DNA that is formed when the DNA duplex is unwound.	tmpzr1t_l9r_go_relaxed.owl	nucleic acid cleavage involved in nucleotide-excision repair|DNA incision involved in nucleotide-excision repair													biological_process											owl:Class	
GO:0090305	biolink:NamedThing	nucleic acid phosphodiester bond hydrolysis	The nucleic acid metabolic process in which the phosphodiester bonds between nucleotides are cleaved by hydrolysis.	tmpzr1t_l9r_go_relaxed.owl	nucleic acid cleavage							tb	2010-04-07T10:26:30Z					biological_process											owl:Class	
GO:0045609	biolink:NamedThing	positive regulation of inner ear auditory receptor cell differentiation	Any process that activates or increases the frequency, rate or extent of auditory hair cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of auditory hair cell differentiation|stimulation of auditory receptor cell differentiation|activation of auditory receptor cell differentiation|up-regulation of auditory receptor cell differentiation|positive regulation of auditory receptor cell differentiation|upregulation of auditory receptor cell differentiation|up regulation of auditory receptor cell differentiation													biological_process											owl:Class	
GO:2000982	biolink:NamedThing	positive regulation of inner ear receptor cell differentiation	Any process that activates or increases the frequency, rate or extent of inner ear receptor cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of inner ear hair cell differentiation							yaf	2011-08-03T02:38:51Z					biological_process											owl:Class	
GO:0003943	biolink:NamedThing	N-acetylgalactosamine-4-sulfatase activity	Catalysis of the hydrolysis of the 4-sulfate groups of the N-acetyl-D-galactosamine 4-sulfate units of chondroitin sulfate and dermatan sulfate.	tmpzr1t_l9r_go_relaxed.owl	N-acetylgalactosamine 4-sulfate sulfohydrolase activity|N-acetylgalactosamine-4-sulphatase activity|acetylgalactosamine 4-sulfatase activity|chondroitinsulfatase|N-acetyl-D-galactosamine-4-sulfate 4-sulfohydrolase activity|arylsulfatase B				Wikipedia:Arylsulfatase_B|MetaCyc:3.1.6.12-RXN|Reactome:R-HSA-1793207|Reactome:R-HSA-2282889|Reactome:R-HSA-9036065|EC:3.1.6.12|Reactome:R-HSA-1606789									molecular_function											owl:Class	
GO:0035973	biolink:NamedThing	aggrephagy	Selective degradation of protein aggregates by macroautophagy.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-08-09T09:53:40Z			GO:0035972		biological_process											owl:Class	
GO:0120288	biolink:NamedThing	negative regulation of aspartic endopeptidase activity, intramembrane cleaving	Any process that decreases the frequency, rate or extent of intramembrane cleaving aspartic-type endopeptidase activity.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/20341						krc	2020-11-19T22:23:52Z					biological_process											owl:Class	
GO:0019806	biolink:NamedThing	bromide peroxidase activity	Catalysis of the reaction: 2 R-H + 2 bromide + hydrogen peroxide = 2 R-Br + 2 H2O. Enzymes with this activity often accept other halide ions as substrates, including chloride and iodide.	tmpzr1t_l9r_go_relaxed.owl	bromoperoxidase activity				EC:1.11.1.18									molecular_function											owl:Class	
GO:1900768	biolink:NamedThing	fonsecin catabolic process	The chemical reactions and pathways resulting in the breakdown of fonsecin.	tmpzr1t_l9r_go_relaxed.owl	fonsecin degradation|fonsecin breakdown|fonsecin catabolism							di	2012-06-04T09:21:38Z					biological_process											owl:Class	
GO:0046164	biolink:NamedThing	alcohol catabolic process	The chemical reactions and pathways resulting in the breakdown of alcohols, any of a class of compounds containing one or more hydroxyl groups attached to a saturated carbon atom.	tmpzr1t_l9r_go_relaxed.owl	alcohol catabolism|alcohol breakdown|alcohol degradation													biological_process											owl:Class	
GO:0008431	biolink:NamedThing	vitamin E binding	Binding to a vitamin E, tocopherol, which includes a series of eight structurally similar compounds. Alpha-tocopherol is the most active form in humans and is a powerful biological antioxidant.	tmpzr1t_l9r_go_relaxed.owl	alpha-tocopherol binding|tocopherol binding													molecular_function											owl:Class	
GO:0051679	biolink:NamedThing	6-alpha-maltosylglucose metabolic process	The chemical reactions and pathways involving 6-alpha-maltosylglucose, also known as isopanose.	tmpzr1t_l9r_go_relaxed.owl	isopanose metabolic process|isopanose metabolism|6-alpha-maltosylglucose metabolism													biological_process											owl:Class	
GO:0003871	biolink:NamedThing	5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity	Catalysis of the reaction: 5-methyltetrahydropteroyltri-L-glutamate + L-homocysteine = L-methionine + tetrahydropteroyltri-L-glutamate.	tmpzr1t_l9r_go_relaxed.owl	cobalamin-independent methionine synthase activity|methyltransferase, tetrahydropteroylglutamate-homocysteine transmethylase activity|tetrahydropteroylglutamate-homocysteine transmethylase activity|methionine synthase (cobalamin-independent) activity|homocysteine methylase activity|MetE|tetrahydropteroyltriglutamate methyltransferase activity|5-methyltetrahydropteroyltri-L-glutamate:L-homocysteine S-methyltransferase activity|methyltetrahydropteroylpolyglutamate:homocysteine methyltransferase activity				EC:2.1.1.14|KEGG_REACTION:R04405|RHEA:21196|MetaCyc:HOMOCYSMET-RXN									molecular_function											owl:Class	
GO:0046082	biolink:NamedThing	5-methylcytosine biosynthetic process	The chemical reactions and pathways resulting in the formation of 5-methylcytosine, a methylated base of DNA.	tmpzr1t_l9r_go_relaxed.owl	5-methylcytosine formation|5-methylcytosine synthesis|5-methylcytosine biosynthesis|5-methylcytosine anabolism													biological_process											owl:Class	
GO:0072528	biolink:NamedThing	pyrimidine-containing compound biosynthetic process	The chemical reactions and pathways resulting in the formation of a pyrimidine-containing compound, i.e. any compound that contains pyrimidine or a formal derivative thereof.	tmpzr1t_l9r_go_relaxed.owl	pyrimidine-containing compound anabolism|pyrimidine and derivative biosynthetic process|pyrimidine-containing compound synthesis|pyrimidine-containing compound biosynthesis|pyrimidine-containing compound formation							mah	2011-01-04T03:27:36Z					biological_process											owl:Class	
GO:0070113	biolink:NamedThing	organellar chromatophore inner membrane	The inner, i.e. lumen-facing, of the two lipid bilayers surrounding an organellar chromatophore.	tmpzr1t_l9r_go_relaxed.owl	Paulinella-type chromatophore inner membrane													cellular_component											owl:Class	
GO:0070112	biolink:NamedThing	organellar chromatophore membrane	Either of the lipid bilayers that surround an organellar chromatophore.	tmpzr1t_l9r_go_relaxed.owl	Paulinella-type chromatophore membrane													cellular_component											owl:Class	
GO:0015068	biolink:NamedThing	glycine amidinotransferase activity	Catalysis of the reaction: L-arginine + glycine = L-ornithine + guanidinoacetate.	tmpzr1t_l9r_go_relaxed.owl	glycine transamidinase activity|arginine-glycine transamidinase activity|arginine-glycine amidinotransferase activity|L-arginine:glycine amidinotransferase activity				MetaCyc:GLYCINE-AMIDINOTRANSFERASE-RXN|EC:2.1.4.1|Reactome:R-HSA-71275|RHEA:13201									molecular_function											owl:Class	
GO:0031169	biolink:NamedThing	ferrichrome biosynthetic process	The chemical reactions and pathways resulting in the formation of a ferrichrome. Ferrichromes are any of a group of growth-promoting Fe(III) chelates formed by various genera of microfungi. They are homodetic cyclic hexapeptides made up of a tripeptide of glycine (or other small neutral amino acids) and a tripeptide of an N'acyl-N4-hydroxy-L-ornithine.	tmpzr1t_l9r_go_relaxed.owl	ferrichrome biosynthetic process, peptide modification|ferrichrome synthesis|ferrichrome biosynthesis|ferrichrome anabolism|ferrichrome formation|ferrichrome biosynthetic process, peptide formation											GO:0031199|GO:0031200		biological_process											owl:Class	
GO:0019539	biolink:NamedThing	hydroxymate-containing siderophore biosynthetic process	The chemical reactions and pathways resulting in the formation of a siderophore from other compounds, including hydroxamic acid. Hydroxamate is one of the three major chemical groups incorporated into siderophore structures with catechol and a-hydroxycarboxylate, each having a high selectivity for iron(3+).	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/20975										GO:0031197|GO:0031198		biological_process											owl:Class	
GO:1905373	biolink:NamedThing	ceramide phosphoethanolamine biosynthetic process	The chemical reactions and pathways resulting in the formation of ceramide phosphoethanolamine.	tmpzr1t_l9r_go_relaxed.owl	ceramide phosphoethanolamine synthesis|ceramide phosphoethanolamine formation|ceramide phosphoethanolamine biosynthesis|ceramide phosphoethanolamine anabolism							hjd	2016-08-16T17:11:12Z					biological_process											owl:Class	
GO:0014713	biolink:NamedThing	negative regulation of branchiomeric skeletal muscle development	Any process that stops, prevents, or reduces the frequency, rate or extent of branchiomeric skeletal muscle development. Branchiomeric skeletal muscle development is the process whose specific outcome is the progression of the branchiomeric skeletal muscle over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0048642	biolink:NamedThing	negative regulation of skeletal muscle tissue development	Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle tissue development.	tmpzr1t_l9r_go_relaxed.owl	downregulation of skeletal muscle development|inhibition of skeletal muscle development|down-regulation of skeletal muscle development|down regulation of skeletal muscle development													biological_process											owl:Class	
GO:0010750	biolink:NamedThing	positive regulation of nitric oxide mediated signal transduction	Any process that increases the rate, frequency or extent of nitric oxide mediated signal transduction. Nitric oxide mediated signal transduction is a series of molecular signals mediated by the detection of nitric oxide (NO).	tmpzr1t_l9r_go_relaxed.owl	positive regulation of nitric oxide-mediated signal transduction													biological_process											owl:Class	
GO:0099136	biolink:NamedThing	chimeric non-reproductive fruiting body development	Development of a non-reproductive fruiting body formed by aggregation of cells with different genotypes.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0099135	biolink:NamedThing	chimeric colonial development	Development a structure consisting of multiple co-operating unicellular organisms of the same species, involving cells of more that one genotype.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0047081	biolink:NamedThing	3-hydroxy-2-methylpyridinecarboxylate dioxygenase activity	Catalysis of the reaction: O2 + NADPH + H+ + 3-hydroxy-2-methylpyridine-5-carboxylate = NADP+ + 2-(acetamidomethylene)succinate.	tmpzr1t_l9r_go_relaxed.owl	methylhydroxypyridine carboxylate dioxygenase activity|3-hydroxy-3-methylpyridinecarboxylate dioxygenase activity|2-methyl-3-hydroxypyridine 5-carboxylic acid dioxygenase activity|3-hydroxy-2-methylpyridine-5-carboxylate,NADPH:oxygen oxidoreductase (decyclizing)|methylhydroxypyridinecarboxylate oxidase activity				MetaCyc:1.14.12.4-RXN|RHEA:10864|EC:1.14.13.242									molecular_function											owl:Class	
GO:0071917	biolink:NamedThing	triose-phosphate transmembrane transporter activity	Enables the transfer of a triose phosphate from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-09-24T10:35:26Z					molecular_function											owl:Class	
GO:1904249	biolink:NamedThing	negative regulation of age-related resistance	Any process that stops, prevents or reduces the extent of age-related resistance.	tmpzr1t_l9r_go_relaxed.owl	down regulation of flowering-induced resistance|downregulation of senescence-induced resistance|down-regulation of adult seedling resistance|downregulation of mature seedling resistance|down-regulation of ARR|downregulation of age-related resistance|negative regulation of ARR|downregulation of ARR|down regulation of mature seedling resistance|inhibition of senescence-induced resistance|down regulation of age-related resistance|inhibition of flowering-induced resistance|inhibition of ARR|down-regulation of flowering-induced resistance|inhibition of age-related resistance|downregulation of adult seedling resistance|negative regulation of adult seedling resistance|downregulation of flowering-induced resistance|down regulation of ARR|inhibition of mature seedling resistance|negative regulation of mature seedling resistance|down regulation of adult seedling resistance|negative regulation of senescence-induced resistance|down-regulation of age-related resistance|down-regulation of senescence-induced resistance|inhibition of adult seedling resistance|negative regulation of flowering-induced resistance|down regulation of senescence-induced resistance|down-regulation of mature seedling resistance							tb	2015-05-19T20:20:05Z					biological_process											owl:Class	
GO:1903020	biolink:NamedThing	positive regulation of glycoprotein metabolic process	Any process that activates or increases the frequency, rate or extent of glycoprotein metabolic process.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of glycoprotein metabolism|positive regulation of glycoprotein metabolism|up regulation of glycoprotein metabolic process|activation of glycoprotein metabolism|activation of glycoprotein metabolic process|upregulation of glycoprotein metabolic process|up-regulation of glycoprotein metabolic process|upregulation of glycoprotein metabolism|up regulation of glycoprotein metabolism					human serum amyloid P component (SAP) P02743 inhibits viral neuraminidase, NA (exo-alpha-sialidase activity) and thus the metabolism of glycoproteins, demonstrated in Figure 4A PMID:23544079, (IDA), the negative regulation term would be applied to this protein		rl	2014-05-14T18:44:31Z					biological_process											owl:Class	
GO:2000862	biolink:NamedThing	negative regulation of estrogen secretion	Any process that stops, prevents or reduces the frequency, rate or extent of estrogen secretion.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of oestrogen secretion							bf	2011-07-26T08:48:28Z					biological_process											owl:Class	
GO:0018695	biolink:NamedThing	4-cresol dehydrogenase (hydroxylating) activity	Catalysis of the reaction: 4-cresol + acceptor + H2O = 4-hydroxybenzaldehyde + reduced acceptor.	tmpzr1t_l9r_go_relaxed.owl	4-cresol:acceptor oxidoreductase (methyl-hydroxylating)|p-cresol-(acceptor) oxidoreductase (hydroxylating) activity|4-cresol dehydrogenase activity|p-cresol methylhydroxylase activity				UM-BBD_reactionID:r0272|EC:1.17.9.1|MetaCyc:1.17.99.1-RXN|RHEA:15141									molecular_function											owl:Class	
GO:0008901	biolink:NamedThing	ferredoxin hydrogenase activity	Catalysis of the reaction: 2 reduced ferredoxin + 2 H+ = 2 oxidized ferredoxin + H2.	tmpzr1t_l9r_go_relaxed.owl	H2 oxidizing hydrogenase|hydrogenase (ferredoxin) activity|bidirectional hydrogenase activity|Ni-Fe hydrogenase activity|Ni-Fe-Se hydrogenase activity|hydrogenlyase activity|nickel-iron hydrogenase activity|[Fe] hydrogenase gamma|iron hydrogenase activity|H2 producing hydrogenase|iron-only hydrogenase activity|H(2) producing hydrogenase activity|hydrogen:ferredoxin oxidoreductase activity|H(2) oxidizing hydrogenase activity|[Fe] hydrogenase activity|hydrogen-lyase activity|nickel-iron-selenium hydrogenase activity|hydrogenase activity|uptake hydrogenase activity|nickel hydrogenase activity|hydrogenase I|hydrogenase II				EC:1.12.7.2|UM-BBD_enzymeID:e0418|MetaCyc:HYDROG-RXN|RHEA:17445	Note that this function was formerly EC:1.12.1.1, EC:1.12.7.1, EC:1.98.1.1, EC:1.18.3.1 and EC:1.18.99.1.						GO:0016950|GO:0016948|GO:0016951|GO:0016949		molecular_function											owl:Class	
GO:0016699	biolink:NamedThing	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which hydrogen acts as an electron donor and reduces an iron-sulfur protein.	tmpzr1t_l9r_go_relaxed.owl	oxidoreductase activity, acting on hydrogen as donor, iron-sulphur protein as acceptor				EC:1.12.7.-							GO:0019110|GO:0016736		molecular_function											owl:Class	
GO:1900924	biolink:NamedThing	negative regulation of glycine import across plasma membrane	Any process that stops, prevents or reduces the frequency, rate or extent of glycine import into a cell.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of glycine import|downregulation of glycine import|negative regulation of glycine import|down regulation of glycine import|inhibition of glycine import							al	2012-06-13T07:40:32Z					biological_process											owl:Class	
GO:0021538	biolink:NamedThing	epithalamus development	The progression of the epithalamus over time from its initial formation until its mature state. The epithalamus is the small dorsomedial area of the thalamus including the habenular nuclei and associated fiber bundles, the pineal body, and the epithelial roof of the third ventricle.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0007563	biolink:NamedThing	regulation of eclosion	Any process that modulates the frequency, rate or extent of the emergence of an insect from a pupa-case or of a larva from an egg.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0080065	biolink:NamedThing	4-alpha-methyl-delta7-sterol oxidation	A lipid oxidation process proceeding through a series of three successive monooxygenations of the alpha methyl group on the C4 carbon (CH3 to CH2OH to CHO to COOH) and resulting in this overall reaction: 4-alpha-methyl-delta7-sterol + 3 NADPH + 3 H+ + 3 O2 = 4-alpha-carboxy,delta7-sterol + 3 NADP+ + 3 H2O.	tmpzr1t_l9r_go_relaxed.owl	4-alpha-methyl-delta7-sterol-4alpha-methyl oxidase activity							dhl	2009-04-13T03:41:50Z					biological_process											owl:Class	
GO:0034440	biolink:NamedThing	lipid oxidation	The removal of one or more electrons from a lipid, with or without the concomitant removal of a proton or protons, by reaction with an electron-accepting substance, by addition of oxygen or by removal of hydrogen.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1904191	biolink:NamedThing	positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in meiotic nuclear division	Any positive regulation of cyclin-dependent protein serine/threonine kinase activity that is involved in meiotic nuclear division.	tmpzr1t_l9r_go_relaxed.owl	upregulation of cyclin-dependent protein kinase activity involved in meiotic nuclear division|activation of cyclin-dependent protein kinase activity involved in meiotic nuclear division|positive regulation of CDK activity involved in meiotic nuclear division|stimulation of cyclin-dependent protein kinase activity involved in meiotic nuclear division|up regulation of cyclin-dependent protein kinase activity involved in meiotic nuclear division|positive regulation of cyclin-dependent protein kinase activity involved in meiosis|up-regulation of cyclin-dependent protein kinase activity involved in meiotic nuclear division							al	2015-05-06T14:48:52Z					biological_process											owl:Class	
GO:0099067	biolink:NamedThing	integral component of presynaptic endosome membrane	The component of the presynaptic endosome membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0031303	biolink:NamedThing	integral component of endosome membrane	The component of the endosome membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.	tmpzr1t_l9r_go_relaxed.owl	integral to endosome membrane													cellular_component											owl:Class	
GO:1900148	biolink:NamedThing	negative regulation of Schwann cell migration	Any process that stops, prevents or reduces the frequency, rate or extent of Schwann cell migration.	tmpzr1t_l9r_go_relaxed.owl	down regulation of Schwann cell migration|downregulation of Schwann cell migration|down-regulation of Schwann cell migration|inhibition of Schwann cell migration							bf	2012-03-06T04:14:55Z					biological_process											owl:Class	
GO:0048107	biolink:NamedThing	4-amino-3-isothiazolidinone biosynthetic process	The chemical reactions and pathways resulting in the formation of 4-amino-3-isothiazolinone, five-membered saturated heterocyclic ring structures containing a sulfur and a nitrogen in the 1-position and 2-positions respectively.	tmpzr1t_l9r_go_relaxed.owl	4-amino-3-isothiazolidinone anabolism|4-amino-3-isothiazolidinone synthesis|4-amino-3-isothiazolidinone formation|4-amino-3-isothiazolidinone biosynthesis													biological_process											owl:Class	
GO:0009511	biolink:NamedThing	plasmodesmatal endoplasmic reticulum	Endoplasmic reticulum found in plasmodesmata, junctions connecting the cytoplasm of adjacent plant cells.	tmpzr1t_l9r_go_relaxed.owl	plasmodesmatal ER													cellular_component											owl:Class	
GO:0005783	biolink:NamedThing	endoplasmic reticulum	The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).	tmpzr1t_l9r_go_relaxed.owl	ER				NIF_Subcellular:sao1036339110|Wikipedia:Endoplasmic_reticulum									cellular_component											owl:Class	
GO:0120001	biolink:NamedThing	apical plasma membrane urothelial plaque	A scallop-shaped plaque, also referred to as an asymmetric unit membrane (AUM), found in the apical plasma membrane of urothelial superficial (umbrella) cells which form a a barrier to the passage of water and soluble toxic compounds found in urine. The plaques are thickened regions of membrane composed of uroplakin transmembrane proteins which form a crystalline array.	tmpzr1t_l9r_go_relaxed.owl	AUM|asymmetric unit membrane	https://github.com/geneontology/go-ontology/issues/12996						krc	2017-02-23T21:10:27Z					cellular_component											owl:Class	
GO:0005887	biolink:NamedThing	integral component of plasma membrane	The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.	tmpzr1t_l9r_go_relaxed.owl	integral to plasma membrane													cellular_component											owl:Class	
GO:0102045	biolink:NamedThing	3-chlorobenzoate-3,4-oxygenase activity	Catalysis of the reaction: 3-chlorobenzoate + O2 + a reduced electron acceptor <=> 3-chlorobenzoate-cis-3,4-diol + an oxidized electron acceptor.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-10422									molecular_function											owl:Class	
GO:1900094	biolink:NamedThing	regulation of transcription from RNA polymerase II promoter involved in determination of left/right symmetry	Any regulation of transcription from RNA polymerase II promoter that is involved in determination of left/right symmetry.	tmpzr1t_l9r_go_relaxed.owl	regulation of transcription from RNA polymerase II promoter, global of determination of left/right symmetry|regulation of transcription from Pol II promoter of determination of left/right asymmetry|regulation of transcription from RNA polymerase II promoter of determination of left/right asymmetry|regulation of global transcription from Pol II promoter of determination of left/right asymmetry|regulation of transcription from RNA polymerase II promoter, global of determination of left/right asymmetry|regulation of transcription from Pol II promoter of determination of left/right symmetry|regulation of gene-specific transcription from RNA polymerase II promoter of determination of left/right symmetry|global transcription regulation from Pol II promoter of determination of left/right asymmetry|regulation of global transcription from Pol II promoter of determination of left/right symmetry|regulation of transcription from RNA polymerase II promoter of determination of left/right symmetry|regulation of gene-specific transcription from RNA polymerase II promoter of determination of left/right asymmetry|global transcription regulation from Pol II promoter of determination of left/right symmetry							vk	2012-02-14T10:58:20Z					biological_process											owl:Class	
GO:2000809	biolink:NamedThing	positive regulation of synaptic vesicle clustering	Any process that activates or increases the frequency, rate or extent of synaptic vesicle clustering.	tmpzr1t_l9r_go_relaxed.owl								pr	2011-07-06T09:50:37Z					biological_process											owl:Class	
GO:0007438	biolink:NamedThing	oenocyte development	The process whose specific outcome is the progression of the oenocyte over time, from its formation to the mature structure. The oenocytes are large secretory cells found in clusters underlying the epidermis of larval abdominal segments.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0006977	biolink:NamedThing	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	A cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage and resulting in the stopping or reduction in rate of the cell cycle.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of cell cycle arrest by p53-mediated DNA damage response													biological_process											owl:Class	
GO:0030330	biolink:NamedThing	DNA damage response, signal transduction by p53 class mediator	A cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage.	tmpzr1t_l9r_go_relaxed.owl	DNA damage response, activation of p53|p53-mediated DNA damage response|TP53 signaling pathway|p53 signaling pathway											GO:0006976		biological_process											owl:Class	
GO:0016011	biolink:NamedThing	dystroglycan complex	A protein complex that includes alpha- and beta-dystroglycan, which are alternative products of the same gene; the laminin-binding component of the dystrophin-associated glycoprotein complex, providing a link between the subsarcolemmal cytoskeleton (in muscle cells) and the extracellular matrix. Alpha-dystroglycan is an extracellular protein binding to alpha-laminin and to beta-dystroglycan; beta-dystroglycan is a transmembrane protein which binds alpha-dystroglycan and dystrophin.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0010586	biolink:NamedThing	miRNA metabolic process	The chemical reactions and pathways involving miRNA, microRNA, a class of single-stranded RNA molecules of about 21-23 nucleotides in length, which regulates gene expression.	tmpzr1t_l9r_go_relaxed.owl	microRNA metabolic process													biological_process											owl:Class	
GO:1990381	biolink:NamedThing	ubiquitin-specific protease binding	Binding to a ubiquitin-specific protease.	tmpzr1t_l9r_go_relaxed.owl	deubiquitinase binding|deubiquitinating enzyme binding							bf	2014-05-19T10:01:53Z					molecular_function											owl:Class	
GO:1901385	biolink:NamedThing	regulation of voltage-gated calcium channel activity	Any process that modulates the frequency, rate or extent of voltage-gated calcium channel activity.	tmpzr1t_l9r_go_relaxed.owl	regulation of depolarization-activated voltage gated calcium channel activity|regulation of depolarization-activated voltage-gated calcium channel activity|regulation of depolarization-activated calcium channel|regulation of voltage-dependent calcium channel activity|regulation of voltage gated calcium channel activity|regulation of dihydropyridine-sensitive calcium channel activity|regulation of depolarization-activated voltage-gated calcium channel|regulation of voltage-gated calcium ion channel activity|regulation of voltage-sensitive calcium channel							vk	2012-10-01T10:34:08Z					biological_process											owl:Class	
GO:0043538	biolink:NamedThing	regulation of actin phosphorylation	Any process that modulates the frequency, rate or extent of the transfer of one or more phosphate groups to an actin molecule.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0032806	biolink:NamedThing	carboxy-terminal domain protein kinase complex	A protein complex that phosphorylates amino acid residues of RNA polymerase II C-terminal domain repeats; phosphorylation occurs mainly on Ser2 and Ser5.	tmpzr1t_l9r_go_relaxed.owl	CTDK complex													cellular_component											owl:Class	
GO:1904459	biolink:NamedThing	negative regulation of substance P secretion	Any process that stops, prevents or reduces the frequency, rate or extent of substance P secretion.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of substance P secretion|down regulation of substance P secretion|downregulation of substance P secretion|inhibition of substance P secretion							sl	2015-07-09T19:32:57Z					biological_process											owl:Class	
GO:0006058	biolink:NamedThing	mannoprotein catabolic process	The chemical reactions and pathways resulting in the breakdown of a mannoprotein, a protein that contains covalently bound mannose residues.	tmpzr1t_l9r_go_relaxed.owl	mannoprotein catabolism|mannoprotein degradation|mannoprotein breakdown													biological_process											owl:Class	
GO:0051603	biolink:NamedThing	proteolysis involved in cellular protein catabolic process	The hydrolysis of a peptide bond or bonds within a protein as part of the chemical reactions and pathways resulting in the breakdown of a protein by individual cells.	tmpzr1t_l9r_go_relaxed.owl	peptidolysis during cellular protein catabolism|peptidolysis during cellular protein catabolic process|peptidolysis involved in cellular protein catabolic process|peptidolysis involved in cellular protein catabolism|proteolysis during cellular protein catabolic process|proteolysis during cellular protein catabolism													biological_process											owl:Class	
GO:0006315	biolink:NamedThing	homing of group II introns	Lateral transfer of a group II intron to a homologous allele that lacks the intron, mediated by a site-specific endonuclease encoded within the mobile intron; group II introns are self-splicing introns with a conserved secondary structure.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0006314	biolink:NamedThing	intron homing	Lateral transfer of an intron to a homologous allele that lacks the intron, mediated by a site-specific endonuclease encoded within the mobile intron.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0034560	biolink:NamedThing	bisphenol A hydroxylase A activity	Catalysis of the reaction: bisphenol A + NADH + H+ + O2 = 2,2-bis(4-hydroxyphenyl)-1-propanol + NAD+ + H2O.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0861|EC:1.14.13.-									molecular_function											owl:Class	
GO:0042356	biolink:NamedThing	GDP-4-dehydro-D-rhamnose reductase activity	Catalysis of the reaction: GDP-6-deoxy-D-mannose + NAD(P)+ = GDP-4-dehydro-6-deoxy-D-mannose + NAD(P)H + H+. In the reverse reaction, a mixture of GDP-D-rhamnose and its C-4 epimer is formed.	tmpzr1t_l9r_go_relaxed.owl	GDP-6-deoxy-D-mannose:NAD(P)+ 4-oxidoreductase activity|GDP-4-keto-D-rhamnose reductase activity|guanosine diphosphate-4-keto-D-rhamnose reductase activity|GDP-4-keto-6-deoxy-D-mannose reductase activity				MetaCyc:GDP-4-DEHYDRO-D-RHAMNOSE-REDUCTASE-RXN|EC:1.1.1.187									molecular_function											owl:Class	
GO:1904320	biolink:NamedThing	positive regulation of smooth muscle contraction involved in micturition	Any process that activates or increases the frequency, rate or extent of smooth muscle contraction involved in micturition.	tmpzr1t_l9r_go_relaxed.owl	activation of smooth muscle contraction involved in urination|up-regulation of urinary bladder smooth muscle contraction involved in micturition|activation of smooth muscle contraction involved in micturition|activation of urinary bladder smooth muscle contraction involved in micturition|upregulation of urinary bladder smooth muscle contraction involved in micturition|positive regulation of urinary bladder smooth muscle contraction involved in micturition|up-regulation of smooth muscle contraction involved in micturition|up regulation of urinary bladder smooth muscle contraction involved in micturition|up regulation of smooth muscle contraction involved in urination|up regulation of smooth muscle contraction involved in micturition|up-regulation of smooth muscle contraction involved in urination|upregulation of smooth muscle contraction involved in urination|positive regulation of smooth muscle contraction involved in urination|upregulation of smooth muscle contraction involved in micturition							sl	2015-06-10T18:46:23Z					biological_process											owl:Class	
GO:0035967	biolink:NamedThing	cellular response to topologically incorrect protein	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a protein that is not folded in its correct three-dimensional structure.	tmpzr1t_l9r_go_relaxed.owl	cellular response to misfolded or unfolded protein							bf	2011-08-03T11:44:50Z					biological_process											owl:Class	
GO:0016079	biolink:NamedThing	synaptic vesicle exocytosis	Fusion of intracellular membrane-bounded vesicles with the pre-synaptic membrane of the neuronal cell resulting in release of neurotransmitter into the synaptic cleft.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0045055	biolink:NamedThing	regulated exocytosis	A process of exocytosis in which soluble proteins and other substances are initially stored in secretory vesicles for later release. It is found mainly in cells that are specialized for secreting products such as hormones, neurotransmitters, or digestive enzymes rapidly on demand.	tmpzr1t_l9r_go_relaxed.owl	regulated secretory pathway													biological_process											owl:Class	
GO:0051006	biolink:NamedThing	positive regulation of lipoprotein lipase activity	Any process that activates or increases the activity of the enzyme lipoprotein lipase.	tmpzr1t_l9r_go_relaxed.owl	up regulation of lipoprotein lipase activity|activation of lipoprotein lipase activity|stimulation of lipoprotein lipase activity|upregulation of lipoprotein lipase activity|up-regulation of lipoprotein lipase activity													biological_process											owl:Class	
GO:0019471	biolink:NamedThing	4-hydroxyproline metabolic process	The chemical reactions and pathways involving 4-hydroxyproline, C5H9NO3, a derivative of the amino acid proline. The presence of hydroxyproline is essential to produce stable triple helical tropocollagen, hence the problems caused by ascorbate deficiency in scurvy. This unusual amino acid is also present in considerable amounts in the major glycoprotein of primary plant cell walls.	tmpzr1t_l9r_go_relaxed.owl	4-hydroxyproline metabolism													biological_process											owl:Class	
GO:0052687	biolink:NamedThing	(3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (ADP-forming) activity	Catalysis of the reaction: (3R)-3-isopropenyl-6-oxoheptanoate + CoA-SH + ATP = H2O + ADP + phosphate + (3R)-3-isopropenyl-6-oxoheptanoyl-CoA.	tmpzr1t_l9r_go_relaxed.owl	3-isopropenyl-6-oxoheptanoyl-CoA synthetase activity				KEGG_REACTION:R06396									molecular_function											owl:Class	
GO:0098970	biolink:NamedThing	postsynaptic neurotransmitter receptor diffusion trapping	The process by which diffusing neurotransmitter receptor becomes trapped at the postsynaptic specialization membrane. This is typically due to interaction with components of the post-synaptic specialization.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0099036	biolink:NamedThing	anchored component of neuronal dense core vesicle membrane	The component of the neuronal dense core vesicle membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:1905209	biolink:NamedThing	positive regulation of cardiocyte differentiation	Any process that activates or increases the frequency, rate or extent of cardiocyte differentiation.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of heart cell differentiation|upregulation of heart cell differentiation|positive regulation of cardiac cell differentiation|up-regulation of cardiac cell differentiation|activation of cardiocyte differentiation|positive regulation of heart cell differentiation|upregulation of cardiac cell differentiation|activation of cardiac cell differentiation|upregulation of cardiocyte differentiation|activation of heart cell differentiation|up regulation of cardiocyte differentiation|up-regulation of cardiocyte differentiation|up regulation of heart cell differentiation|up regulation of cardiac cell differentiation							bc	2016-06-02T07:20:16Z					biological_process											owl:Class	
GO:0060359	biolink:NamedThing	response to ammonium ion	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ammonium stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to ammonia											GO:1903717		biological_process											owl:Class	
GO:0002684	biolink:NamedThing	positive regulation of immune system process	Any process that activates or increases the frequency, rate, or extent of an immune system process.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of immune system process|up regulation of immune system process|upregulation of immune system process|stimulation of immune system process|activation of immune system process													biological_process											owl:Class	
GO:1900630	biolink:NamedThing	methanophenazine biosynthetic process	The chemical reactions and pathways resulting in the formation of methanophenazine.	tmpzr1t_l9r_go_relaxed.owl	methanophenazine synthesis|methanophenazine anabolism|methanophenazine formation|methanophenazine biosynthesis							tt	2012-05-21T06:12:30Z					biological_process											owl:Class	
GO:0003313	biolink:NamedThing	heart rudiment development	The progression of the heart rudiment over time, from its initial formation to the mature structure. The heart rudiment is a cone-like structure that is formed when myocardial progenitor cells of the heart field fuse at the midline. The heart rudiment is the first structure of the heart tube.	tmpzr1t_l9r_go_relaxed.owl	heart cone development							dph	2009-10-27T08:32:40Z					biological_process											owl:Class	
GO:0097324	biolink:NamedThing	melanocyte migration	The orderly movement of melanocytes from one site to another, often during the development of a multicellular organism. A melanocyte is a pigment cell derived from the neural crest. It contains melanin-filled pigment granules, which give a brown to black appearance.	tmpzr1t_l9r_go_relaxed.owl								pr	2012-06-08T10:08:18Z					biological_process											owl:Class	
GO:0099017	biolink:NamedThing	maintenance of protein localization at cell tip	Any process in which localization of a protein is maintained at the cell tip.	tmpzr1t_l9r_go_relaxed.owl	maintenance of protein location at cell tip							dos	2016-06-30T15:17:41Z					biological_process											owl:Class	
GO:0045499	biolink:NamedThing	chemorepellent activity	Providing the environmental signal that initiates the directed movement of a motile cell or organism towards a lower concentration of that signal.	tmpzr1t_l9r_go_relaxed.owl	chemorepellant activity													molecular_function											owl:Class	
GO:0048018	biolink:NamedThing	receptor ligand activity	The activity of a gene product that interacts with a receptor to effect a change in the activity of the receptor. Ligands may be produced by the same, or different, cell that expresses the receptor. Ligands may diffuse extracellularly from their point of origin to the receiving cell, or remain attached to an adjacent cell surface (e.g. Notch ligands).	tmpzr1t_l9r_go_relaxed.owl	vitamin D receptor activator activity|receptor agonist activity|signaling receptor ligand activity|signaling molecule	https://github.com/geneontology/go-ontology/issues/14220						mah	2010-09-13T04:51:59Z			GO:0071884		molecular_function											owl:Class	
GO:0042362	biolink:NamedThing	fat-soluble vitamin biosynthetic process	The chemical reactions and pathways resulting in the formation of any of a diverse group of vitamins that are soluble in organic solvents and relatively insoluble in water.	tmpzr1t_l9r_go_relaxed.owl	fat-soluble vitamin formation|fat-soluble vitamin biosynthesis|fat-soluble vitamin synthesis|fat-soluble vitamin anabolism													biological_process											owl:Class	
GO:0009110	biolink:NamedThing	vitamin biosynthetic process	The chemical reactions and pathways resulting in the formation of a vitamin, one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body.	tmpzr1t_l9r_go_relaxed.owl	vitamin formation|vitamin anabolism|vitamin synthesis|vitamin biosynthesis													biological_process											owl:Class	
GO:1902027	biolink:NamedThing	positive regulation of cartilage condensation	Any process that activates or increases the frequency, rate or extent of cartilage condensation.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of cartilage condensation|up regulation of cartilage condensation|activation of cartilage condensation|upregulation of cartilage condensation							jl	2013-03-28T17:02:46Z					biological_process											owl:Class	
GO:2000464	biolink:NamedThing	positive regulation of astrocyte chemotaxis	Any process that activates or increases the frequency, rate or extent of astrocyte chemotaxis.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-03-04T04:43:29Z					biological_process											owl:Class	
GO:2000458	biolink:NamedThing	regulation of astrocyte chemotaxis	Any process that modulates the frequency, rate or extent of astrocyte chemotaxis.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-03-04T10:53:50Z					biological_process											owl:Class	
GO:2001045	biolink:NamedThing	negative regulation of integrin-mediated signaling pathway	Any process that stops, prevents or reduces the frequency, rate or extent of integrin-mediated signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of integrin-mediated signalling pathway							bf	2011-08-31T03:49:16Z					biological_process											owl:Class	
GO:2001152	biolink:NamedThing	negative regulation of renal water transport	Any process that stops, prevents or reduces the frequency, rate or extent of renal water transport.	tmpzr1t_l9r_go_relaxed.owl								yaf	2011-10-24T11:37:57Z					biological_process											owl:Class	
GO:0018641	biolink:NamedThing	6-hydroxy-3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity	Catalysis of the reaction: 6-hydroxy-3-methyl-2-oxo-1,2-dihydroquinoline + O2 + 2 H+ + 2 e- = H2O + 5,6-dihydroxy-3-methyl-2-oxo-1,2-dihydroquinoline.	tmpzr1t_l9r_go_relaxed.owl					EC:1.14.13.-|UM-BBD_reactionID:r0048									molecular_function											owl:Class	
GO:0072757	biolink:NamedThing	cellular response to camptothecin	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a camptothecin stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to CPT							mah	2012-11-07T12:12:35Z					biological_process											owl:Class	
GO:1901563	biolink:NamedThing	response to camptothecin	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a camptothecin stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to CPT							mah	2012-11-02T15:32:45Z					biological_process											owl:Class	
GO:0010639	biolink:NamedThing	negative regulation of organelle organization	Any process that decreases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of organelle organisation|negative regulation of organelle organization and biogenesis													biological_process											owl:Class	
GO:1905608	biolink:NamedThing	positive regulation of presynapse assembly	Any process that activates or increases the frequency, rate or extent of presynapse assembly.	tmpzr1t_l9r_go_relaxed.owl	up regulation of presynapse biogenesis|up-regulation of presynapse assembly|up regulation of presynaptic terminal assembly|up regulation of presynapse assembly|up-regulation of presynaptic terminal assembly|positive regulation of presynaptic terminal assembly|upregulation of presynaptic terminal assembly|activation of presynapse biogenesis|upregulation of presynapse assembly|up-regulation of presynapse biogenesis|activation of presynapse assembly|activation of presynaptic terminal assembly|positive regulation of presynapse biogenesis|upregulation of presynapse biogenesis							bc	2016-10-27T16:08:28Z					biological_process											owl:Class	
GO:1905606	biolink:NamedThing	regulation of presynapse assembly	Any process that modulates the frequency, rate or extent of presynapse assembly.	tmpzr1t_l9r_go_relaxed.owl	regulation of presynapse biogenesis|regulation of presynaptic terminal assembly							bc	2016-10-27T16:08:13Z					biological_process											owl:Class	
GO:0075220	biolink:NamedThing	positive regulation of zoospore encystment on host	Any process that activates, maintains or increases the frequency, rate or extent of zoospore encystment on host. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0001800	biolink:NamedThing	negative regulation of type IIb hypersensitivity	Any process that stops, prevents, or reduces the rate of type IIb hypersensitivity, a type of inflammatory response.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of type IIb hypersensitivity|inhibition of type IIb hypersensitivity|downregulation of type IIb hypersensitivity|down regulation of type IIb hypersensitivity													biological_process											owl:Class	
GO:1905513	biolink:NamedThing	negative regulation of short-term synaptic potentiation	Any process that stops, prevents or reduces the frequency, rate or extent of short-term synaptic potentiation.	tmpzr1t_l9r_go_relaxed.owl	inhibition of synaptic facilitation|negative regulation of synaptic facilitation|down-regulation of synaptic facilitation|down regulation of short-term synaptic potentiation|inhibition of short-term synaptic potentiation|down regulation of synaptic facilitation|downregulation of synaptic facilitation|down-regulation of short-term synaptic potentiation|downregulation of short-term synaptic potentiation							hjd	2016-09-28T17:40:23Z					biological_process											owl:Class	
GO:1900801	biolink:NamedThing	cspyrone B1 catabolic process	The chemical reactions and pathways resulting in the breakdown of cspyrone B1.	tmpzr1t_l9r_go_relaxed.owl	cspyrone B1 breakdown|cspyrone B1 catabolism|cspyrone B1 degradation							di	2012-06-04T09:50:58Z					biological_process											owl:Class	
GO:0032085	biolink:NamedThing	regulation of type II site-specific deoxyribonuclease activity	Any process that modulates the frequency, rate or extent of a type II restriction endodeoxyribonuclease activity.	tmpzr1t_l9r_go_relaxed.owl	regulation of type II restriction endodeoxyribonuclease activity|type II restriction endodeoxyribonuclease regulator|type II restriction enzyme regulator													biological_process											owl:Class	
GO:0032072	biolink:NamedThing	regulation of restriction endodeoxyribonuclease activity	Any process that modulates the frequency, rate or extent of a restriction endodeoxyribonuclease activity, the catalysis of endonucleolytic cleavage of DNA in a site-specific manner, resulting in double-strand breaks.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0061906	biolink:NamedThing	autophagosome localization	Any process in which an autophagosome is transported to, and/or maintained in, a specific location within the cell.	tmpzr1t_l9r_go_relaxed.owl								dph	2017-06-28T17:27:57Z					biological_process											owl:Class	
GO:1990849	biolink:NamedThing	vacuolar localization	Any process in which the vacuole is transported to, and/or maintained in, a specific location within the cell.	tmpzr1t_l9r_go_relaxed.owl	maintenance of vacuolar localization|maintenance of vacuole location|maintenance of vacuole localization|maintenance of vacuolar location	https://github.com/geneontology/go-ontology/issues/22182						mcc	2015-09-10T08:16:02Z					biological_process											owl:Class	
GO:0071633	biolink:NamedThing	dihydroceramidase activity	Catalysis of the reaction: a dihydroceramide + H2O = a fatty acid + dihydrosphingosine.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-02-11T04:24:12Z					molecular_function											owl:Class	
GO:0017040	biolink:NamedThing	N-acylsphingosine amidohydrolase activity	Catalysis of the reaction: N-acylsphingosine + H2O = a fatty acid + sphingosine.	tmpzr1t_l9r_go_relaxed.owl	acylsphingosine deacylase activity|glycosphingolipid ceramide deacylase				EC:3.5.1.23|Reactome:R-HSA-428205|Reactome:R-HSA-1606602|RHEA:20856|Reactome:R-HSA-1606583|MetaCyc:CERAMIDASE-RXN|Reactome:R-HSA-428231									molecular_function											owl:Class	
GO:0103087	biolink:NamedThing	methylthiopentylmalate dehydrogenase activity	Catalysis of the reaction: 3-(5'-methylthio)pentylmalate <=> H+ + 2-oxo-8-methylthiooctanoate + carbon dioxide.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXNQT-4171									molecular_function											owl:Class	
GO:0019744	biolink:NamedThing	hopanoid metabolic process	The chemical reactions and pathways involving hopanoids, pentacyclic sterol-like compounds based on the hopane nucleus.	tmpzr1t_l9r_go_relaxed.owl	hopanoid metabolism													biological_process											owl:Class	
GO:0071335	biolink:NamedThing	hair follicle cell proliferation	The multiplication or reproduction of hair follicle cells, resulting in the expansion of a cell population.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-12-11T10:49:53Z					biological_process											owl:Class	
GO:0005145	biolink:NamedThing	interleukin-14 receptor binding	Binding to an interleukin-14 receptor.	tmpzr1t_l9r_go_relaxed.owl	IL-14|interleukin-14 receptor ligand													molecular_function											owl:Class	
GO:0019555	biolink:NamedThing	glutamate catabolic process to ornithine	The chemical reactions and pathways resulting in the breakdown of glutamate into other compounds, including ornithine.	tmpzr1t_l9r_go_relaxed.owl	glutamate degradation to ornithine|glutamate breakdown to ornithine				MetaCyc:GLUTORN-PWY									biological_process											owl:Class	
GO:0033723	biolink:NamedThing	fluoroacetaldehyde dehydrogenase activity	Catalysis of the reaction: fluoroacetaldehyde + NAD+ + H2O = fluoroacetate + NADH + 2 H+.	tmpzr1t_l9r_go_relaxed.owl	fluoroacetaldehyde:NAD+ oxidoreductase activity				RHEA:16677|EC:1.2.1.69									molecular_function											owl:Class	
GO:1902750	biolink:NamedThing	negative regulation of cell cycle G2/M phase transition	Any signalling pathway that decreases or inhibits the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to M phase of the cell cycle.	tmpzr1t_l9r_go_relaxed.owl	downregulation of cell cycle G2/M phase transition|down-regulation of cell cycle G2/M phase transition|inhibition of cell cycle G2/M phase transition|down regulation of cell cycle G2/M phase transition							jl	2014-03-05T15:38:21Z					biological_process											owl:Class	
GO:1901988	biolink:NamedThing	negative regulation of cell cycle phase transition	Any process that stops, prevents or reduces the frequency, rate or extent of cell cycle phase transition.	tmpzr1t_l9r_go_relaxed.owl	down regulation of cell cycle transition|inhibition of cell cycle transition|downregulation of cell cycle phase transition|inhibition of cell cycle phase transition|down regulation of cell cycle phase transition|down-regulation of cell cycle phase transition|negative regulation of cell cycle transition|downregulation of cell cycle transition|down-regulation of cell cycle transition							jl	2013-03-19T16:11:32Z					biological_process											owl:Class	
GO:1904528	biolink:NamedThing	positive regulation of microtubule binding	Any process that activates or increases the frequency, rate or extent of microtubule binding.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of microtubule/chromatin interaction|up-regulation of microtubule severing activity|upregulation of microtubule binding|upregulation of microtubule severing activity|up regulation of microtubule binding|up-regulation of microtubule binding|activation of microtubule severing activity|positive regulation of microtubule severing activity|upregulation of microtubule/chromatin interaction|activation of microtubule binding|activation of microtubule/chromatin interaction|positive regulation of microtubule/chromatin interaction|up regulation of microtubule severing activity|up regulation of microtubule/chromatin interaction							als	2015-07-30T10:32:36Z					biological_process											owl:Class	
GO:0060828	biolink:NamedThing	regulation of canonical Wnt signaling pathway	Any process that modulates the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin, the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes.	tmpzr1t_l9r_go_relaxed.owl	regulation of canonical Wnt receptor signalling pathway|regulation of Wnt receptor signaling pathway through beta-catenin|regulation of catenin protein nuclear translocation|regulation of catenin import into nucleus|regulation of canonical Wnt receptor signaling pathway|catenin import into nucleus|regulation of canonical Wnt-activated signaling pathway	https://github.com/geneontology/go-ontology/issues/13686|https://github.com/geneontology/go-ontology/issues/15268						dph	2009-08-11T01:54:47Z			GO:0035411|GO:0035412		biological_process											owl:Class	
GO:2000167	biolink:NamedThing	regulation of planar cell polarity pathway involved in neural tube closure	Any process that modulates the frequency, rate or extent of planar cell polarity pathway involved in neural tube closure.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-10-05T01:08:53Z					biological_process											owl:Class	
GO:0033085	biolink:NamedThing	negative regulation of T cell differentiation in thymus	Any process that stops, prevents, or reduces the frequency, rate or extent of T cell differentiation in the thymus.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of thymic T cell differentiation|negative regulation of thymocyte cell differentiation|negative regulation of thymocyte differentiation|negative regulation of T cell development in thymus					Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.								biological_process											owl:Class	
GO:2000220	biolink:NamedThing	regulation of pseudohyphal growth	Any process that modulates the frequency, rate or extent of pseudohyphal growth.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-11-03T04:36:56Z					biological_process											owl:Class	
GO:0070784	biolink:NamedThing	regulation of growth of unicellular organism as a thread of attached cells	Any process that modulates the frequency, rate or extent of the process in which cells remain attached after division and form thread-like filaments that may penetrate into a solid growth medium.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-07-07T02:34:59Z					biological_process											owl:Class	
GO:0007549	biolink:NamedThing	dosage compensation	Compensating for the variation in the unpaired sex chromosome:autosome chromosome ratios between sexes by activation or inactivation of genes on one or both of the sex chromosomes.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Dosage_compensation									biological_process											owl:Class	
GO:0040029	biolink:NamedThing	regulation of gene expression, epigenetic	A process that modulates the frequency, rate or extent of gene expression by remodelling of chromatin by either modifying the chromatin fiber, the nucleosomal histones, or the DNA. Once established, this regulation may be maintained over many cell divisions. It can also be heritable in the absence of the instigating signal.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/22201												biological_process											owl:Class	
GO:0007315	biolink:NamedThing	pole plasm assembly	Establishment of the specialized cytoplasm found at the poles of the egg. An example of this is found in Drosophila melanogaster.	tmpzr1t_l9r_go_relaxed.owl												GO:0048113		biological_process											owl:Class	
GO:0036157	biolink:NamedThing	outer dynein arm	Outer arm structure present on the outer doublet microtubules of ciliary and flagellar axonemes. Outer dynein arms contain 2-3 heavy chains, two or more intermediate chains and a cluster of 4-8 light chains. Inner and outer dynein arms have different functions in the generation of microtubule-based motility.	tmpzr1t_l9r_go_relaxed.owl	outer dynein arm complex							bf	2012-03-21T01:25:03Z					cellular_component											owl:Class	
GO:1902133	biolink:NamedThing	(+)-secoisolariciresinol metabolic process	The chemical reactions and pathways involving (+)-secoisolariciresinol.	tmpzr1t_l9r_go_relaxed.owl	(+)-secoisolariciresinol metabolism							ms	2013-05-21T08:50:04Z					biological_process											owl:Class	
GO:0005767	biolink:NamedThing	secondary lysosome	Vacuole formed by the fusion of a lysosome with an organelle (autosome) or with a primary phagosome.	tmpzr1t_l9r_go_relaxed.owl					NIF_Subcellular:sao1549842807									cellular_component											owl:Class	
GO:0005764	biolink:NamedThing	lysosome	A small lytic vacuole that has cell cycle-independent morphology found in most animal cells and that contains a variety of hydrolases, most of which have their maximal activities in the pH range 5-6. The contained enzymes display latency if properly isolated. About 40 different lysosomal hydrolases are known and lysosomes have a great variety of morphologies and functions.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Lysosome|NIF_Subcellular:sao585356902									cellular_component											owl:Class	
GO:0038133	biolink:NamedThing	ERBB2-ERBB3 signaling pathway	A series of molecular signals initiated by binding of a ligand to a ERBB3 receptor on the surface of a cell, followed by transmission of the signal by a heterodimeric complex of ERBB2 and ERBB3. ERBB2, which does not bind any known ligand, is activated through formation of a heterodimer with another ligand-activated ERBB family member such as ERBB3. ERBB3 also has impaired kinase activity and relies on ERBB2 for activation and signal transmission.	tmpzr1t_l9r_go_relaxed.owl	ERBB2-ERBB3 signalling pathway|HER2-HER3 signaling pathway							bf	2012-03-30T11:10:44Z					biological_process											owl:Class	
GO:0038129	biolink:NamedThing	ERBB3 signaling pathway	A series of molecular signals initiated by binding of a ligand to the tyrosine kinase receptor ERBB3 on the surface of a cell. The pathway ends with regulation of a downstream cellular process, e.g. transcription. ERBB3 receptors have impaired kinase activity and rely on the kinase activity of the heterodimer partner for activation and signal transmission.	tmpzr1t_l9r_go_relaxed.owl	receptor tyrosine-protein kinase erbB-3 signaling pathway|HER3 signaling pathway|ERBB3 signalling pathway							bf	2012-03-30T10:42:28Z					biological_process											owl:Class	
GO:0061098	biolink:NamedThing	positive regulation of protein tyrosine kinase activity	Any process that increases the rate, frequency, or extent of protein tyrosine kinase activity.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-04-26T02:34:53Z					biological_process											owl:Class	
GO:1900687	biolink:NamedThing	negative regulation of gerfelin biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of gerfelin biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	inhibition of gerfelin synthesis|down-regulation of gerfelin synthesis|downregulation of gerfelin synthesis|down regulation of gerfelin biosynthetic process|downregulation of gerfelin biosynthetic process|down regulation of gerfelin formation|down-regulation of gerfelin anabolism|down regulation of gerfelin synthesis|negative regulation of gerfelin synthesis|inhibition of gerfelin biosynthetic process|downregulation of gerfelin biosynthesis|downregulation of gerfelin anabolism|downregulation of gerfelin formation|down-regulation of gerfelin biosynthesis|down regulation of gerfelin anabolism|down regulation of gerfelin biosynthesis|inhibition of gerfelin biosynthesis|negative regulation of gerfelin anabolism|down-regulation of gerfelin formation|inhibition of gerfelin formation|negative regulation of gerfelin formation|inhibition of gerfelin anabolism|down-regulation of gerfelin biosynthetic process|negative regulation of gerfelin biosynthesis							di	2012-05-22T04:50:05Z					biological_process											owl:Class	
GO:0048678	biolink:NamedThing	response to axon injury	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an axon injury stimulus.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0032693	biolink:NamedThing	negative regulation of interleukin-10 production	Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-10 production.	tmpzr1t_l9r_go_relaxed.owl	down regulation of interleukin-10 production|downregulation of interleukin-10 production|negative regulation of interleukin-10 secretion|inhibition of interleukin-10 production|negative regulation of IL-10 production|negative regulation of interleukin-10 biosynthetic process|down-regulation of interleukin-10 production											GO:0045081|GO:2001180		biological_process											owl:Class	
GO:0032653	biolink:NamedThing	regulation of interleukin-10 production	Any process that modulates the frequency, rate, or extent of interleukin-10 production.	tmpzr1t_l9r_go_relaxed.owl	regulation of IL-10 production|regulation of interleukin-10 biosynthetic process|regulation of interleukin-10 secretion											GO:0045074|GO:2001179		biological_process											owl:Class	
GO:1904461	biolink:NamedThing	ergosteryl 3-beta-D-glucoside metabolic process	The chemical reactions and pathways involving ergosteryl 3-beta-D-glucoside.	tmpzr1t_l9r_go_relaxed.owl	ergosteryl 3-beta-D-glucoside metabolism							mcc	2015-07-09T19:36:19Z					biological_process											owl:Class	
GO:1901804	biolink:NamedThing	beta-glucoside metabolic process	The chemical reactions and pathways involving beta-glucoside.	tmpzr1t_l9r_go_relaxed.owl	beta-glucoside metabolism							yaf	2013-01-22T10:10:21Z					biological_process											owl:Class	
GO:0102885	biolink:NamedThing	alpha-cuprenene synthase activity	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate <=> (-)-alpha-cuprenene + diphosphoric acid.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-8426|EC:4.2.3.95|RHEA:32027									molecular_function											owl:Class	
GO:0051681	biolink:NamedThing	6-alpha-maltosylglucose catabolic process	The chemical reactions and pathways resulting in the breakdown of 6-alpha-maltosylglucose, also known as isopanose.	tmpzr1t_l9r_go_relaxed.owl	isopanose catabolism|isopanose catabolic process													biological_process											owl:Class	
GO:0002608	biolink:NamedThing	negative regulation of myeloid dendritic cell antigen processing and presentation	Any process that stops, prevents, or reduces the frequency, rate, or extent of myeloid dendritic cell antigen processing and presentation.	tmpzr1t_l9r_go_relaxed.owl	down regulation of myeloid dendritic cell antigen processing and presentation|inhibition of myeloid dendritic cell antigen processing and presentation|down-regulation of myeloid dendritic cell antigen processing and presentation|downregulation of myeloid dendritic cell antigen processing and presentation													biological_process											owl:Class	
GO:0005330	biolink:NamedThing	dopamine:sodium symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: dopamine(out) + Na+(out) + Cl-(out)= dopamine(in) + Na+(in) + Cl-(in).	tmpzr1t_l9r_go_relaxed.owl	sodium/dopamine symporter activity|dopamine:sodium:chloride symporter activity|dopamine transmembrane transporter activity	https://github.com/geneontology/go-ontology/issues/16054										GO:0005329		molecular_function											owl:Class	
GO:0008504	biolink:NamedThing	monoamine transmembrane transporter activity	Enables the transfer of monoamines, organic compounds that contain one amino group that is connected to an aromatic ring by an ethylene group (-CH2-CH2-), from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-444160|Reactome:R-HSA-380586|Reactome:R-HSA-372542|Reactome:R-HSA-5660706|Reactome:R-HSA-379393|Reactome:R-HSA-380620							GO:0015201		molecular_function											owl:Class	
GO:0051295	biolink:NamedThing	establishment of meiotic spindle localization	The cell cycle process in which the directed movement of the meiotic spindle to a specific location in the cell occurs.	tmpzr1t_l9r_go_relaxed.owl	meiotic spindle positioning|spindle positioning involved in meiotic cell cycle|establishment of meiotic spindle localisation|spindle positioning during meiosis													biological_process											owl:Class	
GO:0034387	biolink:NamedThing	4-aminobutyrate:pyruvate transaminase activity	Catalysis of the reaction: 4-aminobutanoate + pyruvate = succinate semialdehyde + alanine.	tmpzr1t_l9r_go_relaxed.owl	gamma-aminobutyric acid pyruvate transaminase activity				EC:2.6.1.96|RHEA:32263|MetaCyc:RXN-6902									molecular_function											owl:Class	
GO:0003867	biolink:NamedThing	4-aminobutyrate transaminase activity	Catalysis of the reaction: 4-aminobutanoate + amino group acceptor = succinate semialdehyde + amino acid.	tmpzr1t_l9r_go_relaxed.owl	gamma-aminobutyric acid transaminase activity|gamma-aminobutyrate transaminase activity|4-aminobutanoate transaminase activity|aminobutyrate aminotransferase activity|gamma-amino-N-butyrate transaminase activity|aminobutyrate transaminase activity|gamma-aminobutyric acid aminotransferase activity|GABA transferase activity|4-aminobutyrate aminotransferase activity|4-aminobutyric acid aminotransferase activity|gamma-aminobutyrate aminotransaminase activity|GABA transaminase activity|glutamate-succinic semialdehyde transaminase activity|gamma-aminobutyric transaminase activity|beta-alanine aminotransferase|GABA aminotransferase activity				Reactome:R-HSA-916855|RHEA:23352|MetaCyc:GABATRANSAM-RXN									molecular_function											owl:Class	
GO:0120111	biolink:NamedThing	neuron projection cytoplasm	All of the contents of a plasma membrane bounded neuron projection, excluding the plasma membrane surrounding the projection.	tmpzr1t_l9r_go_relaxed.owl								krc	2017-11-01T18:58:12Z					cellular_component											owl:Class	
GO:0032838	biolink:NamedThing	plasma membrane bounded cell projection cytoplasm	All of the contents of a plasma membrane bounded cell projection, excluding the plasma membrane surrounding the projection.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:1904312	biolink:NamedThing	cellular response to gold(3+)	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gold(3+) stimulus.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-06-10T17:41:13Z					biological_process											owl:Class	
GO:1904311	biolink:NamedThing	response to gold(3+)	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gold(3+) stimulus.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-06-10T17:41:07Z					biological_process											owl:Class	
GO:0075251	biolink:NamedThing	uredospore formation	The process which specific outcome is the formation of an asexual, dikaryotic, often rusty-colored spore, produced in a structure called a uredinium; mostly found in the rust fungus.	tmpzr1t_l9r_go_relaxed.owl	urediniospore formation|ureidospore formation													biological_process											owl:Class	
GO:0043936	biolink:NamedThing	asexual sporulation resulting in formation of a cellular spore	The formation of a cellular spore derived from the products of mitosis. A cellular spore is a cell form that can be used for dissemination, for survival of adverse conditions because of its heat and dessication resistance, and/or for reproduction.	tmpzr1t_l9r_go_relaxed.owl	asexual sporulation resulting in the formation of a viable spore|asexual reproduction resulting in the formation of a cellular spore													biological_process											owl:Class	
GO:2001002	biolink:NamedThing	positive regulation of xylan catabolic process	Any process that activates or increases the frequency, rate or extent of xylan catabolic process.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of xylan catabolism|positive regulation of xylan degradation|positive regulation of xylan breakdown							tt	2011-08-08T03:23:22Z					biological_process											owl:Class	
GO:2000926	biolink:NamedThing	positive regulation of cellodextrin metabolic process	Any process that activates or increases the frequency, rate or extent of cellodextrin metabolic process.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of cellodextrin metabolism							tt	2011-08-01T12:39:59Z					biological_process											owl:Class	
GO:0051126	biolink:NamedThing	negative regulation of actin nucleation	Any process that stops, prevents, or reduces the frequency, rate or extent of actin nucleation, the initial step in the formation of an actin filament in which actin monomers combine to form a new filament.	tmpzr1t_l9r_go_relaxed.owl	down regulation of actin nucleation|down-regulation of actin nucleation|inhibition of actin nucleation|downregulation of actin nucleation													biological_process											owl:Class	
GO:1902904	biolink:NamedThing	negative regulation of supramolecular fiber organization	Any process that stops, prevents or reduces the frequency, rate or extent of fibril organization.	tmpzr1t_l9r_go_relaxed.owl	inhibition of fibril organisation|inhibition of fibril organization|negative regulation of fibril organisation|downregulation of fibril organization|down-regulation of fibril organization|down regulation of fibril organisation|downregulation of fibril organisation|down regulation of fibril organization|down-regulation of fibril organisation					HSPA8, human, P11142 in PMID:23921388 inferred from direct assay to negatively regulate fibrillation of alpha-Syn in vitro		rl	2014-04-15T16:46:42Z					biological_process											owl:Class	
GO:1904181	biolink:NamedThing	positive regulation of membrane depolarization	Any process that activates or increases the frequency, rate or extent of membrane depolarization.	tmpzr1t_l9r_go_relaxed.owl	upregulation of membrane depolarization|up-regulation of membrane depolarization|up regulation of membrane depolarization|activation of membrane depolarization							sl	2015-04-29T22:29:31Z					biological_process											owl:Class	
GO:1902364	biolink:NamedThing	negative regulation of protein localization to spindle pole body	Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to spindle pole body.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of protein localization to spindle pole body|down regulation of protein localisation to spindle pole body|downregulation of protein localization to spindle pole body|inhibition of protein localisation to spindle pole body|downregulation of protein localisation to spindle pole body|negative regulation of protein localisation to spindle pole body|down regulation of protein localization to spindle pole body|inhibition of protein localization to spindle pole body|down-regulation of protein localisation to spindle pole body							vw	2013-08-15T16:38:23Z					biological_process											owl:Class	
GO:1903465	biolink:NamedThing	positive regulation of mitotic cell cycle DNA replication	Any process that activates or increases the frequency, rate or extent of mitotic cell cycle DNA replication.	tmpzr1t_l9r_go_relaxed.owl	activation of DNA replication during S phase involved in mitotic cell cycle|up-regulation of DNA replication involved in S phase involved in mitotic cell cycle|upregulation of DNA replication during S phase involved in mitotic cell cycle|upregulation of DNA replication involved in S-phase involved in mitotic cell cycle|upregulation of mitotic cell cycle DNA replication|positive regulation of nuclear cell cycle DNA replication involved in mitotic cell cycle|positive regulation of DNA replication during S phase involved in mitotic cell cycle|activation of mitotic nuclear cell cycle DNA replication|activation of DNA replication involved in S phase involved in mitotic cell cycle|up regulation of DNA replication during S phase involved in mitotic cell cycle|up-regulation of nuclear cell cycle DNA replication involved in mitotic cell cycle|positive regulation of DNA replication involved in S-phase involved in mitotic cell cycle|activation of nuclear cell cycle DNA replication involved in mitotic cell cycle|up regulation of DNA replication involved in S-phase involved in mitotic cell cycle|up regulation of DNA replication involved in S phase involved in mitotic cell cycle|activation of mitotic cell cycle DNA replication|up-regulation of mitotic cell cycle DNA replication|up-regulation of DNA replication involved in S-phase involved in mitotic cell cycle|up-regulation of mitotic nuclear cell cycle DNA replication|upregulation of mitotic nuclear cell cycle DNA replication|up regulation of nuclear cell cycle DNA replication involved in mitotic cell cycle|positive regulation of DNA replication involved in S phase involved in mitotic cell cycle|positive regulation of mitotic nuclear cell cycle DNA replication|upregulation of DNA replication involved in S phase involved in mitotic cell cycle|up regulation of mitotic nuclear cell cycle DNA replication|up regulation of mitotic cell cycle DNA replication|upregulation of nuclear cell cycle DNA replication involved in mitotic cell cycle|activation of DNA replication involved in S-phase involved in mitotic cell cycle|up-regulation of DNA replication during S phase involved in mitotic cell cycle							vw	2014-09-23T13:38:41Z					biological_process											owl:Class	
GO:0036107	biolink:NamedThing	4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate metabolic process	The chemical reactions and pathways involving 4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate, a precursor of 4-amino-4-deoxy-L-arabinose (L-Ara4N).	tmpzr1t_l9r_go_relaxed.owl	undecaprenyl phosphate alpha-L-Ara4N metabolism|4-amino-4-deoxy-alpha-L-arabinose undecaprenyl phosphate metabolic process							bf	2012-02-06T02:55:42Z					biological_process											owl:Class	
GO:0006721	biolink:NamedThing	terpenoid metabolic process	The chemical reactions and pathways involving terpenoids, any member of a class of compounds characterized by an isoprenoid chemical structure and including derivatives with various functional groups.	tmpzr1t_l9r_go_relaxed.owl	terpenoid metabolism													biological_process											owl:Class	
GO:0042819	biolink:NamedThing	vitamin B6 biosynthetic process	The chemical reactions and pathways resulting in the formation of any of the vitamin B6 compounds; pyridoxal, pyridoxamine and pyridoxine and the active form, pyridoxal phosphate.	tmpzr1t_l9r_go_relaxed.owl	pyridoxine-5'-phosphate biosynthesis|vitamin B6 formation|vitamin B6 anabolism|vitamin B6 biosynthesis|vitamin B6 synthesis													biological_process											owl:Class	
GO:0072525	biolink:NamedThing	pyridine-containing compound biosynthetic process	The chemical reactions and pathways resulting in the formation of a pyridine-containing compound, i.e. any compound that contains pyridine or a formal derivative thereof.	tmpzr1t_l9r_go_relaxed.owl	pyridine-containing compound anabolism|pyridine-containing compound formation|pyridine-containing compound synthesis|pyridine-containing compound biosynthesis|pyridine and derivative biosynthetic process							mah	2011-01-04T03:23:01Z					biological_process											owl:Class	
GO:0090282	biolink:NamedThing	positive regulation of transcription involved in G2/M transition of mitotic cell cycle	Any process that activates or increases the frequency, rate or extent of transcription of target genes that are transcribed as part of the G2/M transition of the mitotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl	activation of G2/M-specific transcription in the mitotic cell cycle|positive regulation of transcription from RNA polymerase II promoter during G2/M-phase of the mitotic cell cycle|up-regulation of transcription from RNA polymerase II promoter during G2/M transition of the mitotic cell cycle|up-regulation of G2/M-specific transcription in the mitotic cell cycle|activation of transcription from RNA polymerase II promoter during G2/M-phase of the mitotic cell cycle|positive regulation of G2/M-specific transcription in the mitotic cell cycle|up-regulation of transcription involved in G2/M transition of mitotic cell cycle|activation of transcription involved in G2/M transition of mitotic cell cycle							tb	2010-02-09T02:13:26Z					biological_process											owl:Class	
GO:0033034	biolink:NamedThing	positive regulation of myeloid cell apoptotic process	Any process that activates or increases the frequency, rate, or extent of myeloid cell apoptotic process.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of myeloid cell apoptosis|stimulation of myeloid cell apoptosis|up regulation of myeloid cell apoptosis|up-regulation of myeloid cell apoptosis|upregulation of myeloid cell apoptosis|activation of myeloid cell apoptosis													biological_process											owl:Class	
GO:0071590	biolink:NamedThing	nicotinamide riboside biosynthetic process	The chemical reactions and pathways resulting in the formation of nicotinamide riboside, the product of the formation of a glycosidic bond between ribose and nicotinamide.	tmpzr1t_l9r_go_relaxed.owl	N-ribosylnicotinamide biosynthetic process|nicotinamide riboside biosynthesis|nicotinamide riboside anabolism|nicotinamide riboside synthesis|nicotinamide riboside formation							mah	2010-01-29T11:39:27Z					biological_process											owl:Class	
GO:0046495	biolink:NamedThing	nicotinamide riboside metabolic process	The chemical reactions and pathways involving nicotinamide riboside, the product of the formation of a glycosidic bond between ribose and nicotinamide.	tmpzr1t_l9r_go_relaxed.owl	nicotinamide riboside metabolism|N-ribosylnicotinamide metabolic process													biological_process											owl:Class	
GO:1903924	biolink:NamedThing	estradiol binding	Binding to estradiol.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-02-11T00:11:34Z					molecular_function											owl:Class	
GO:0005496	biolink:NamedThing	steroid binding	Binding to a steroid, any of a large group of substances that have in common a ring system based on 1,2-cyclopentanoperhydrophenanthrene.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0032869	biolink:NamedThing	cellular response to insulin stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin stimulus. Insulin is a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0008250	biolink:NamedThing	oligosaccharyltransferase complex	A protein complex that is found in the endoplasmic reticulum membrane of eukaryotes and transfers lipid-linked oligosaccharide precursor to asparagine residues on nascent proteins. In yeast, the complex includes at least nine different subunits, whereas in mammalian cells at least three different forms of the complex have been detected.	tmpzr1t_l9r_go_relaxed.owl	OST complex|oligosaccharyl transferase complex													cellular_component											owl:Class	
GO:0050761	biolink:NamedThing	depsipeptide metabolic process	The chemical reactions and pathways involving depsipeptides, a linear or cyclic compound composed of both amino acids and hydroxy acids in peptide and ester bonds respectively.	tmpzr1t_l9r_go_relaxed.owl	depsipeptide metabolism													biological_process											owl:Class	
GO:0072599	biolink:NamedThing	establishment of protein localization to endoplasmic reticulum	The directed movement of a protein to a specific location in the endoplasmic reticulum.	tmpzr1t_l9r_go_relaxed.owl	establishment of protein localization to ER|establishment of protein localisation to ER|establishment of protein localisation to endoplasmic reticulum|establishment of protein localization in endoplasmic reticulum							mah	2011-02-14T02:23:41Z					biological_process											owl:Class	
GO:0060957	biolink:NamedThing	endocardial cell fate commitment	The commitment of a cell to an endocardial cell fate and its capacity to differentiate into an endocardial cell. An endocardial cell is a specialized endothelial cell that makes up the endocardium portion of the heart.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-09-29T03:24:29Z					biological_process											owl:Class	
GO:0032883	biolink:NamedThing	regulation of chitin biosynthetic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of chitin.	tmpzr1t_l9r_go_relaxed.owl	regulation of chitin synthesis|regulation of chitin anabolism|regulation of chitin biosynthesis|regulation of chitin formation													biological_process											owl:Class	
GO:0008480	biolink:NamedThing	sarcosine dehydrogenase activity	Catalysis of the reaction: sarcosine + H2O + electron-transfer flavoprotein = glycine + formaldehyde + reduced electron-transfer flavoprotein.	tmpzr1t_l9r_go_relaxed.owl	monomethylglycine dehydrogenase activity|sarcosine:(acceptor) oxidoreductase (demethylating)|sarcosine:acceptor oxidoreductase (demethylating)|sarcosine N-demethylase activity				KEGG_REACTION:R00611|RHEA:19793|Reactome:R-HSA-6797913|MetaCyc:SARCOSINE-DEHYDROGENASE-RXN|EC:1.5.8.3	Note that this was EC:1.5.99.1.								molecular_function											owl:Class	
GO:1905087	biolink:NamedThing	positive regulation of bioluminescence	Any process that activates or increases the frequency, rate or extent of bioluminescence.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of bioluminescence|up regulation of bioluminescence|upregulation of bioluminescence|activation of bioluminescence							rph	2016-03-29T07:51:27Z					biological_process											owl:Class	
GO:1905085	biolink:NamedThing	regulation of bioluminescence	Any process that modulates the frequency, rate or extent of bioluminescence.	tmpzr1t_l9r_go_relaxed.owl								rph	2016-03-29T07:51:07Z					biological_process											owl:Class	
GO:1903662	biolink:NamedThing	L-altrarate metabolic process	The chemical reactions and pathways involving L-altrarate.	tmpzr1t_l9r_go_relaxed.owl	L-altrarate(1-) metabolism							jl	2014-11-26T14:34:20Z					biological_process											owl:Class	
GO:0019577	biolink:NamedThing	aldaric acid metabolic process	The chemical reactions and pathways involving aldaric acid, any dicarboxylic acid formed by oxidation of by the terminal groups of an aldose to carboxyl group.	tmpzr1t_l9r_go_relaxed.owl	aldaric acid metabolism													biological_process											owl:Class	
GO:0072303	biolink:NamedThing	positive regulation of glomerular metanephric mesangial cell proliferation	Any process that increases the frequency, rate or extent of metanephric glomerular mesangial cell proliferation.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-04-09T05:03:41Z					biological_process											owl:Class	
GO:0072301	biolink:NamedThing	regulation of metanephric glomerular mesangial cell proliferation	Any process that modulates the frequency, rate or extent of metanephric glomerular mesangial cell proliferation.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-04-09T05:03:41Z					biological_process											owl:Class	
GO:2000773	biolink:NamedThing	negative regulation of cellular senescence	Any process that stops, prevents or reduces the frequency, rate or extent of cellular senescence.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-06-22T01:57:08Z					biological_process											owl:Class	
GO:1901997	biolink:NamedThing	negative regulation of indoleacetic acid biosynthetic process via tryptophan	Any process that stops, prevents or reduces the frequency, rate or extent of indoleacetic acid biosynthetic process via tryptophan.	tmpzr1t_l9r_go_relaxed.owl	downregulation of IAA biosynthetic process via tryptophan|down regulation of indoleacetic acid synthesis via tryptophan|downregulation of indoleacetic acid formation via tryptophan|inhibition of indoleacetic acid anabolism via tryptophan|negative regulation of IAA biosynthetic process via tryptophan|downregulation of indoleacetic acid anabolism via tryptophan|down-regulation of indoleacetic acid anabolism via tryptophan|down-regulation of indoleacetic acid synthesis via tryptophan|down regulation of IAA biosynthetic process via tryptophan|down-regulation of indoleacetic acid biosynthetic process via tryptophan|negative regulation of indoleacetic acid anabolism via tryptophan|inhibition of IAA biosynthetic process via tryptophan|downregulation of indoleacetic acid biosynthetic process via tryptophan|inhibition of indoleacetic acid formation via tryptophan|negative regulation of indoleacetic acid formation via tryptophan|inhibition of indoleacetic acid synthesis via tryptophan|down-regulation of indoleacetic acid formation via tryptophan|downregulation of indoleacetic acid synthesis via tryptophan|down regulation of indoleacetic acid formation via tryptophan|down regulation of indoleacetic acid anabolism via tryptophan|negative regulation of indoleacetic acid synthesis via tryptophan|down regulation of indoleacetic acid biosynthetic process via tryptophan|inhibition of indoleacetic acid biosynthetic process via tryptophan|down-regulation of IAA biosynthetic process via tryptophan							tb	2013-03-19T19:14:13Z					biological_process											owl:Class	
GO:1901996	biolink:NamedThing	regulation of indoleacetic acid biosynthetic process via tryptophan	Any process that modulates the frequency, rate or extent of indoleacetic acid biosynthetic process via tryptophan.	tmpzr1t_l9r_go_relaxed.owl	regulation of IAA biosynthetic process via tryptophan|regulation of indoleacetic acid anabolism via tryptophan|regulation of indoleacetic acid synthesis via tryptophan|regulation of indoleacetic acid formation via tryptophan							tb	2013-03-19T19:14:09Z					biological_process											owl:Class	
GO:0002859	biolink:NamedThing	negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target	Any process that stops, prevents, or reduces the frequency, rate, or extent of natural killer cell mediated cytotoxicity directed against tumor cell target.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of natural killer cell mediated cytotoxicity directed against tumor cell target|inhibition of natural killer cell mediated cytotoxicity directed against tumor cell target|down regulation of natural killer cell mediated cytotoxicity directed against tumor cell target|downregulation of natural killer cell mediated cytotoxicity directed against tumor cell target													biological_process											owl:Class	
GO:1903676	biolink:NamedThing	positive regulation of cap-dependent translational initiation	Any process that activates or increases the frequency, rate or extent of cap-dependent translational initiation.	tmpzr1t_l9r_go_relaxed.owl	upregulation of cap-dependent translational initiation|up-regulation of cap-dependent translational initiation|activation of cap-dependent translational initiation|up regulation of cap-dependent translational initiation							bf	2014-11-27T19:50:39Z					biological_process											owl:Class	
GO:1903674	biolink:NamedThing	regulation of cap-dependent translational initiation	Any process that modulates the frequency, rate or extent of cap-dependent translational initiation.	tmpzr1t_l9r_go_relaxed.owl								bf	2014-11-27T19:50:23Z					biological_process											owl:Class	
GO:2000570	biolink:NamedThing	positive regulation of T-helper 2 cell activation	Any process that activates or increases the frequency, rate or extent of T-helper 2 cell activation.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of Th2 cell activation							ebc	2011-04-03T09:14:59Z					biological_process											owl:Class	
GO:0047130	biolink:NamedThing	saccharopine dehydrogenase (NADP+, L-lysine-forming) activity	Catalysis of the reaction: L-saccharopine + H(2)O + NADP(+) = 2-oxoglutarate + L-lysine + H(+) + NADPH.	tmpzr1t_l9r_go_relaxed.owl	L-lysine-alpha-ketoglutarate reductase activity|lysine:alpha-ketoglutarate:TPNH oxidoreductase (epsilon-N-[gultaryl-2]-L-lysine forming)|6-N-(L-1,3-dicarboxypropyl)-L-lysine:NADP+ oxidoreductase (L-lysine-forming)|saccharopine (nicotinamide adenine dinucleotide phosphate, lysine-forming) dehydrogenase activity|N6-(L-1,3-dicarboxypropyl)-L-lysine:NADP+ oxidoreductase (L-lysine-forming)				Reactome:R-HSA-70938|KEGG_REACTION:R00716|RHEA:19373|MetaCyc:1.5.1.8-RXN|EC:1.5.1.8							GO:0010010		molecular_function											owl:Class	
GO:0004753	biolink:NamedThing	saccharopine dehydrogenase activity	Catalysis of the cleavage of N6-(L-1,3-dicarboxypropyl)-L-lysine to release an amino acid (lysine or glutamate), with the concomitant reduction of an electron acceptor.	tmpzr1t_l9r_go_relaxed.owl	lysine-ketoglutarate reductase activity|lysine-2-oxoglutarate reductase activity													molecular_function											owl:Class	
GO:2000955	biolink:NamedThing	negative regulation of cyclodextrin metabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of cyclodextrin metabolic process.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of cyclodextrin metabolism							tt	2011-08-01T02:22:05Z					biological_process											owl:Class	
GO:0052679	biolink:NamedThing	terpentetriene synthase activity	Catalysis of the reaction: terpentedienyl diphosphate = diphosphate + terpentetriene.	tmpzr1t_l9r_go_relaxed.owl	terpentedienyl-diphosphate diphosphate-lyase (terpentetriene-forming) activity				EC:4.2.3.36|MetaCyc:RXN-9455|RHEA:25617									molecular_function											owl:Class	
GO:1903312	biolink:NamedThing	negative regulation of mRNA metabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of mRNA metabolic process.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of mRNA metabolism|inhibition of mRNA metabolic process|down regulation of mRNA metabolic process|inhibition of mRNA metabolism|down-regulation of mRNA metabolic process|downregulation of mRNA metabolism|down-regulation of mRNA metabolism|downregulation of mRNA metabolic process|down regulation of mRNA metabolism							vw	2014-08-18T11:52:34Z					biological_process											owl:Class	
GO:0015387	biolink:NamedThing	potassium:proton symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: K+(out) + H+(out) = K+(in) + H+(in).	tmpzr1t_l9r_go_relaxed.owl	potassium:hydrogen symporter activity				RHEA:28490									molecular_function											owl:Class	
GO:0015079	biolink:NamedThing	potassium ion transmembrane transporter activity	Enables the transfer of potassium ions (K+) from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	potassium uptake permease activity|potassium transporter activity|potassium uptake transmembrane transporter activity				RHEA:29463							GO:0022817|GO:0015388		molecular_function											owl:Class	
GO:1900949	biolink:NamedThing	positive regulation of isoprene biosynthetic process	Any process that activates or increases the frequency, rate or extent of isoprene biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	upregulation of hemiterpene biosynthetic process|up-regulation of 2-methyl-1,3-butadiene biosynthesis|activation of isoprene biosynthetic process|activation of 2-methyl-1,3-butadiene biosynthetic process|up regulation of hemiterpene biosynthetic process|up-regulation of 2-methyl-1,3-butadiene biosynthetic process|positive regulation of hemiterpene biosynthesis|up-regulation of isoprene biosynthetic process|upregulation of hemiterpene biosynthesis|positive regulation of 2-methyl-1,3-butadiene biosynthesis|activation of hemiterpene biosynthesis|upregulation of isoprene biosynthetic process|up-regulation of hemiterpene biosynthesis|up-regulation of hemiterpene biosynthetic process|positive regulation of 2-methyl-1,3-butadiene biosynthetic process|activation of 2-methyl-1,3-butadiene biosynthesis|up regulation of 2-methyl-1,3-butadiene biosynthetic process|up regulation of 2-methyl-1,3-butadiene biosynthesis|activation of hemiterpene biosynthetic process|upregulation of 2-methyl-1,3-butadiene biosynthesis|up regulation of hemiterpene biosynthesis|up regulation of isoprene biosynthetic process|positive regulation of hemiterpene biosynthetic process|upregulation of 2-methyl-1,3-butadiene biosynthetic process							tt	2012-06-14T03:21:54Z					biological_process											owl:Class	
GO:1900946	biolink:NamedThing	positive regulation of isoprene metabolic process	Any process that activates or increases the frequency, rate or extent of isoprene metabolic process.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of isoprene metabolism|activation of 2-methyl-1,3-butadiene metabolism|positive regulation of hemiterpene metabolism|up regulation of 2-methyl-1,3-butadiene metabolic process|activation of 2-methyl-1,3-butadiene metabolic process|activation of isoprene metabolic process|positive regulation of hemiterpene metabolic process|up regulation of hemiterpene metabolism|positive regulation of 2-methyl-1,3-butadiene metabolic process|activation of hemiterpene metabolism|positive regulation of isoprene metabolism|upregulation of isoprene metabolism|up-regulation of 2-methyl-1,3-butadiene metabolism|up-regulation of hemiterpene metabolic process|up-regulation of isoprene metabolic process|up-regulation of 2-methyl-1,3-butadiene metabolic process|activation of isoprene metabolism|activation of hemiterpene metabolic process|upregulation of 2-methyl-1,3-butadiene metabolism|upregulation of hemiterpene metabolic process|upregulation of isoprene metabolic process|upregulation of hemiterpene metabolism|up-regulation of hemiterpene metabolism|upregulation of 2-methyl-1,3-butadiene metabolic process|up regulation of isoprene metabolism|up regulation of hemiterpene metabolic process|up regulation of isoprene metabolic process|positive regulation of 2-methyl-1,3-butadiene metabolism|up regulation of 2-methyl-1,3-butadiene metabolism							tt	2012-06-14T03:19:41Z					biological_process											owl:Class	
GO:1904759	biolink:NamedThing	protein localization to equatorial microtubule organizing center	A process in which a protein is transported to, or maintained in, a location within an equatorial microtubule organizing center.	tmpzr1t_l9r_go_relaxed.owl	protein localisation in equatorial microtubule organizing center|protein localization in equatorial microtubule organizing center|protein localisation to equatorial microtubule organizing center|protein localization to eMTOC							mah	2015-10-21T12:37:55Z					biological_process											owl:Class	
GO:1905508	biolink:NamedThing	protein localization to microtubule organizing center	A process in which a protein is transported to, or maintained in, a location within a microtubule organizing center.	tmpzr1t_l9r_go_relaxed.owl	protein localization in microtubule organizing center|protein localisation in microtubule organizing center|protein localisation to microtubule organizing center							mah	2016-09-28T12:32:16Z					biological_process											owl:Class	
GO:0000506	biolink:NamedThing	glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex	An enzyme complex that catalyzes the transfer of GlcNAc from UDP-GlcNAc to an acceptor phosphatidylinositol, the first step in the production of GPI anchors for cell surface proteins. The complex contains PIG-A, PIG-C, PIG-H, PIG-Q, PIG-P, and DPM2 in human, and Eri1p, Gpi1p, Gpi2p, Gpi15p, Gpi19p, and Spt14p in budding yeast.	tmpzr1t_l9r_go_relaxed.owl	GPI-GnT complex|GPI-N-acetylglucosaminyltransferase complex|GPI-GlcNAc transferase complex					Note that this term should not be confused with 'GPI-anchor transamidase complex ; GO:0042765', which represents a distinct complex with a different catalytic activity.								cellular_component											owl:Class	
GO:0007208	biolink:NamedThing	phospholipase C-activating serotonin receptor signaling pathway	The series of molecular signals generated as a consequence of a serotonin receptor binding to its physiological ligand, where the pathway proceeds with activation of phospholipase C (PLC) and a subsequent release of inositol trisphosphate (IP3) and diacylglycerol (DAG).	tmpzr1t_l9r_go_relaxed.owl	activation of phospholipase C activity by serotonin receptor signalling pathway|serotonin receptor, phospholipase C activating pathway|activation of phospholipase C activity by serotonin receptor signaling pathway													biological_process											owl:Class	
GO:0007200	biolink:NamedThing	phospholipase C-activating G protein-coupled receptor signaling pathway	The series of molecular signals generated as a consequence of a G protein-coupled receptor binding to its physiological ligand, where the pathway proceeds with activation of phospholipase C (PLC) and a subsequent increase in the concentration of inositol trisphosphate (IP3) and diacylglycerol (DAG).	tmpzr1t_l9r_go_relaxed.owl	G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)|G-protein coupled receptor signaling pathway coupled to IP3 second messenger|G protein signalling, coupled to IP3 second messenger (phospholipase C activating)|G protein signaling, coupled to IP3 second messenger (phospholipase C activating)|PLC-activating GPCR signaling pathway|phospholipase C-activating dopamine receptor signaling pathway|G-protein signalling, coupled to IP3 second messenger (phospholipase C activating)|phospholipase C-activating G-protein coupled receptor signaling pathway|activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger					This term is intended to cover steps in a GPCR signaling pathway both upstream and downstream of phospholipase C (PLC) activity.								biological_process											owl:Class	
GO:2000950	biolink:NamedThing	positive regulation of xyloglucan metabolic process	Any process that activates or increases the frequency, rate or extent of xyloglucan metabolic process.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of xyloglucan metabolism							tt	2011-08-01T02:17:02Z					biological_process											owl:Class	
GO:0010219	biolink:NamedThing	regulation of vernalization response	Any process that modulates the frequency, rate or extent of the vernalization response, by which induction of flowering is normally caused by extended exposure to cold temperatures.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1904534	biolink:NamedThing	negative regulation of telomeric loop disassembly	Any process that stops, prevents or reduces the frequency, rate or extent of telomeric loop disassembly.	tmpzr1t_l9r_go_relaxed.owl	down regulation of telomeric loop disassembly|downregulation of telomeric loop disassembly|inhibition of telomeric loop disassembly|downregulation of T loop disassembly|negative regulation of T loop disassembly|inhibition of T loop disassembly|down-regulation of T loop disassembly|down regulation of T loop disassembly|down-regulation of telomeric loop disassembly							nc	2015-07-31T17:15:04Z					biological_process											owl:Class	
GO:1904533	biolink:NamedThing	regulation of telomeric loop disassembly	Any process that modulates the frequency, rate or extent of telomeric loop disassembly.	tmpzr1t_l9r_go_relaxed.owl	regulation of T loop disassembly							nc	2015-07-31T17:14:58Z					biological_process											owl:Class	
GO:0032343	biolink:NamedThing	aldosterone catabolic process	The chemical reactions and pathways resulting in the breakdown of aldosterone, a corticosteroid hormone that is produced by the zona glomerulosa of the adrenal cortex and regulates salt (sodium and potassium) and water balance.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0032341	biolink:NamedThing	aldosterone metabolic process	The chemical reactions and pathways involving aldosterone, a corticosteroid hormone that is produced by the zona glomerulosa of the adrenal cortex and regulates salt (sodium and potassium) and water balance.	tmpzr1t_l9r_go_relaxed.owl	aldosterone metabolism													biological_process											owl:Class	
GO:0160004	biolink:NamedThing	poly-ADP-D-ribose modification-dependent protein binding	Binding to a protein upon poly-ADP-ribosylation of the target protein.	tmpzr1t_l9r_go_relaxed.owl						This term should only be used when the binding is shown to require a poly-ADP-D-ribose post-translational modification: the interaction needs to be tested with and without the PTM. The binding does not need to be at the site of the ADP-D-ribose modification. It may be that the PTM causes a conformational change that allows binding of the protein to another region; this type of modification-dependent protein binding is valid for annotation to this term.		rl	2021-07-12T23:36:00Z					molecular_function											owl:Class	
GO:0110057	biolink:NamedThing	regulation of blood vessel endothelial cell differentiation	Any process that modulates the frequency, rate or extent of blood vessel endothelial cell differentiation.	tmpzr1t_l9r_go_relaxed.owl								kmv	2017-10-23T14:32:09Z					biological_process											owl:Class	
GO:2000909	biolink:NamedThing	regulation of sterol import	Any process that modulates the frequency, rate or extent of sterol import.	tmpzr1t_l9r_go_relaxed.owl	regulation of sterol influx|regulation of sterol uptake							bf	2011-07-29T01:25:10Z					biological_process											owl:Class	
GO:0032371	biolink:NamedThing	regulation of sterol transport	Any process that modulates the frequency, rate or extent of the directed movement of sterols into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1903025	biolink:NamedThing	regulation of RNA polymerase II regulatory region sequence-specific DNA binding	Any process that modulates the frequency, rate or extent of RNA polymerase II regulatory region sequence-specific DNA binding.	tmpzr1t_l9r_go_relaxed.owl								dph	2014-05-15T17:55:54Z					biological_process											owl:Class	
GO:2000677	biolink:NamedThing	regulation of transcription regulatory region DNA binding	Any process that modulates the frequency, rate or extent of transcription regulatory region DNA binding.	tmpzr1t_l9r_go_relaxed.owl								yaf	2011-05-09T03:28:11Z					biological_process											owl:Class	
GO:0106244	biolink:NamedThing	eupatolide synthase activity	Catalysis of the reaction: 8beta-hydroxygermacra-1(10),4,11(13)-trien-12-oate + O2 + reduced [NADPH--hemoprotein reductase] = eupatolide + 2 H2O + oxidized [NADPH--hemoprotein reductase].	tmpzr1t_l9r_go_relaxed.owl					RHEA:57972|EC:1.14.14.169			hjd	2019-12-20T14:50:15Z					molecular_function											owl:Class	
GO:0102183	biolink:NamedThing	avenastenone reductase activity	Catalysis of the reaction: avenastenone + NADPH + H+ <=> avenasterol + NADP.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-11939									molecular_function											owl:Class	
GO:1903620	biolink:NamedThing	positive regulation of transdifferentiation	Any process that activates or increases the frequency, rate or extent of transdifferentiation.	tmpzr1t_l9r_go_relaxed.owl	activation of transdifferentiation|up regulation of transdifferentiation|up-regulation of transdifferentiation|upregulation of transdifferentiation							jl	2014-11-19T11:25:14Z					biological_process											owl:Class	
GO:1903869	biolink:NamedThing	negative regulation of methylenetetrahydrofolate reductase (NAD(P)H) activity	Any process that stops, prevents or reduces the frequency, rate or extent of methylenetetrahydrofolate reductase (NAD(P)H) activity.	tmpzr1t_l9r_go_relaxed.owl	inhibition of methylenetetrahydrofolate reductase (NADPH(2)) activity|down-regulation of MetF|downregulation of 5,10-methylenetetrahydrofolate reductase (FADH(2)) activity|inhibition of 5,10-methylenetetrahydrofolate reductase (FADH) activity|downregulation of N5,10-methylenetetrahydrofolate reductase activity|down-regulation of N5,10-methylenetetrahydrofolate reductase activity|negative regulation of 5-methyltetrahydrofolate:NAD oxidoreductase activity|inhibition of 5-methyltetrahydrofolate:NAD(+) oxidoreductase activity|down-regulation of 5,10-CH(2)-H(4)folate reductase activity|downregulation of 5,10-CH2-H4folate reductase activity|down regulation of 5,10-CH2-H4folate reductase activity|down regulation of methylenetetrahydrofolate reductase (NADPH(2)) activity|downregulation of 5,10-methylenetetrahydrofolate reductase (NADPH) activity|negative regulation of 5,10-methylenetetrahydrofolate reductase (FADH(2)) activity|downregulation of methylenetetrahydrofolate reductase (NADPH(2)) activity|inhibition of 5,10-methylenetetrahydrofolate reductase (FADH(2)) activity|down regulation of N5,N10-methylenetetrahydrofolate reductase activity|down-regulation of methylenetetrahydrofolate reductase (NADPH(2)) activity|down regulation of 5-methyltetrahydrofolate:(acceptor) oxidoreductase activity|negative regulation of 5,10-methylenetetrahydrofolate reductase (FADH) activity|downregulation of methylenetetrahydrofolate reductase (NAD(P)H) activity|negative regulation of 5,10-methylenetetrahydrofolate reductase (NADPH) activity|inhibition of N5,10-methylenetetrahydrofolate reductase activity|inhibition of N5,N10-methylenetetrahydrofolate reductase activity|down-regulation of 5,10-methylenetetrahydropteroylglutamate reductase activity|negative regulation of 5-methyltetrahydrofolate:NAD+ oxidoreductase activity|inhibition of methylenetetrahydrofolate (reduced riboflavin adenine dinucleotide) reductase activity|negative regulation of methylenetetrahydrofolate reductase [NAD(P)H]|down-regulation of 5,10-methylenetetrahydrofolate reductase (FADH(2)) activity|downregulation of 5-methyltetrahydrofolate:NADP(+) oxidoreductase activity|negative regulation of 5-methyltetrahydrofolate:NAD(+) oxidoreductase activity|downregulation of 5-methyltetrahydrofolate:(acceptor) oxidoreductase activity|inhibition of 5,10-methylenetetrahydrofolate reductase (FADH2) activity|downregulation of methylenetetrahydrofolate reductase (NADPH2)|negative regulation of 5-methyltetrahydrofolate:NADP+ oxidoreductase activity|negative regulation of N5,N10-methylenetetrahydrofolate reductase activity|down regulation of 5,10-methylenetetrahydrofolate reductase (FADH2) activity|down regulation of methylenetetrahydrofolate (reduced nicotinamide adenine dinucleotide phosphate) reductase activity|inhibition of 5-methyltetrahydrofolate:(acceptor) oxidoreductase activity|down-regulation of 5-methyltetrahydrofolate:NAD+ oxidoreductase activity|down regulation of methylenetetrahydrofolate reductase (NADPH2)|negative regulation of 5-methyltetrahydrofolate:NADP(+) oxidoreductase activity|negative regulation of 5,10-CH(2)-H(4)folate reductase activity|inhibition of 5-methyltetrahydrofolate:NAD(P)+ oxidoreductase activity|down-regulation of 5,10-methylenetetrahydrofolate reductase (FADH) activity|downregulation of methylenetetrahydrofolate (reduced nicotinamide adenine dinucleotide phosphate) reductase activity|down regulation of 5,10-CH(2)-H(4)folate reductase activity|down regulation of 5-methyltetrahydrofolate:NADP+ oxidoreductase activity|negative regulation of 5,10-methylenetetrahydropteroylglutamate reductase activity|negative regulation of 5-methyltetrahydrofolate:NAD(P)+ oxidoreductase activity|down-regulation of 5-methyltetrahydrofolate:NAD(P)+ oxidoreductase activity|inhibition of 5-methyltetrahydrofolate:NAD oxidoreductase activity|down-regulation of 5,10-methylenetetrahydrofolate reductase (FADH2) activity|negative regulation of N5,10-methylenetetrahydrofolate reductase activity|down regulation of 5,10-methylenetetrahydrofolate reductase (FADH) activity|down regulation of MetF|inhibition of 5-methyltetrahydrofolate:NADP(+) oxidoreductase activity|down regulation of N5,10-methylenetetrahydrofolate reductase activity|down-regulation of methylenetetrahydrofolate (reduced nicotinamide adenine dinucleotide phosphate) reductase activity|down-regulation of methylenetetrahydrofolate reductase (NADPH2)|down-regulation of 5-methyltetrahydrofolate:(acceptor) oxidoreductase activity|downregulation of 5,10-methylenetetrahydrofolate reductase (FADH2) activity|down-regulation of methylenetetrahydrofolate (reduced riboflavin adenine dinucleotide) reductase activity|downregulation of 5-methyltetrahydrofolate:NAD oxidoreductase activity|downregulation of 5-methyltetrahydrofolate:NAD+ oxidoreductase activity|down-regulation of 5-methyltetrahydrofolate:NADP+ oxidoreductase activity|negative regulation of 5,10-methylenetetrahydrofolate reductase (FADH2) activity|down-regulation of methylenetetrahydrofolate reductase (NAD(P)H) activity|down regulation of 5,10-methylenetetrahydrofolate reductase (FADH(2)) activity|negative regulation of methylenetetrahydrofolate (reduced nicotinamide adenine dinucleotide phosphate) reductase activity|inhibition of methylenetetrahydrofolate reductase [NAD(P)H]|negative regulation of 5-methyltetrahydrofolate:(acceptor) oxidoreductase activity|downregulation of 5,10-methylenetetrahydropteroylglutamate reductase activity|inhibition of 5-methyltetrahydrofolate:NAD+ oxidoreductase activity|downregulation of 5-methyltetrahydrofolate:NADP+ oxidoreductase activity|down regulation of 5,10-methylenetetrahydrofolate reductase (NADPH) activity|inhibition of 5,10-CH(2)-H(4)folate reductase activity|down regulation of 5-methyltetrahydrofolate:NAD oxidoreductase activity|inhibition of methylenetetrahydrofolate reductase (NADPH2)|downregulation of 5,10-methylenetetrahydrofolate reductase (FADH) activity|down-regulation of 5-methyltetrahydrofolate:NAD(+) oxidoreductase activity|down-regulation of 5,10-CH2-H4folate reductase activity|inhibition of 5-methyltetrahydrofolate:NADP+ oxidoreductase activity|inhibition of 5,10-CH2-H4folate reductase activity|negative regulation of MetF|downregulation of 5-methyltetrahydrofolate:NAD(P)+ oxidoreductase activity|down-regulation of 5,10-methylenetetrahydrofolate reductase (NADPH) activity|down-regulation of 5-methyltetrahydrofolate:NAD oxidoreductase activity|inhibition of methylenetetrahydrofolate reductase (NAD(P)H) activity|inhibition of 5,10-methylenetetrahydropteroylglutamate reductase activity|down-regulation of N5,N10-methylenetetrahydrofolate reductase activity|negative regulation of 5,10-CH2-H4folate reductase activity|inhibition of 5,10-methylenetetrahydrofolate reductase (NADPH) activity|inhibition of methylenetetrahydrofolate (reduced nicotinamide adenine dinucleotide phosphate) reductase activity|negative regulation of methylenetetrahydrofolate reductase (NADPH(2)) activity|down-regulation of 5-methyltetrahydrofolate:NADP(+) oxidoreductase activity|down-regulation of methylenetetrahydrofolate reductase [NAD(P)H]|down regulation of 5-methyltetrahydrofolate:NADP(+) oxidoreductase activity|downregulation of 5,10-CH(2)-H(4)folate reductase activity|downregulation of methylenetetrahydrofolate reductase [NAD(P)H]|down regulation of methylenetetrahydrofolate (reduced riboflavin adenine dinucleotide) reductase activity|down regulation of 5,10-methylenetetrahydropteroylglutamate reductase activity|down regulation of methylenetetrahydrofolate reductase (NAD(P)H) activity|negative regulation of methylenetetrahydrofolate reductase (NADPH2)|down regulation of 5-methyltetrahydrofolate:NAD(+) oxidoreductase activity|down regulation of 5-methyltetrahydrofolate:NAD+ oxidoreductase activity|downregulation of MetF|inhibition of MetF|downregulation of N5,N10-methylenetetrahydrofolate reductase activity|negative regulation of methylenetetrahydrofolate (reduced riboflavin adenine dinucleotide) reductase activity|downregulation of 5-methyltetrahydrofolate:NAD(+) oxidoreductase activity|downregulation of methylenetetrahydrofolate (reduced riboflavin adenine dinucleotide) reductase activity|down regulation of methylenetetrahydrofolate reductase [NAD(P)H]|down regulation of 5-methyltetrahydrofolate:NAD(P)+ oxidoreductase activity							rph	2015-02-05T13:26:25Z					biological_process											owl:Class	
GO:1903868	biolink:NamedThing	regulation of methylenetetrahydrofolate reductase (NAD(P)H) activity	Any process that modulates the frequency, rate or extent of methylenetetrahydrofolate reductase (NAD(P)H) activity.	tmpzr1t_l9r_go_relaxed.owl	regulation of 5-methyltetrahydrofolate:NADP+ oxidoreductase activity|regulation of 5-methyltetrahydrofolate:NAD(+) oxidoreductase activity|regulation of methylenetetrahydrofolic acid reductase activity|regulation of methylenetetrahydrofolate reductase (NADPH2)|regulation of methylenetetrahydrofolate reductase activity|regulation of 5,10-methylenetetrahydrofolate reductase (FADH(2)) activity|regulation of methylenetetrahydrofolate reductase (NADPH(2)) activity|regulation of 5-methyltetrahydrofolate:NAD(P)+ oxidoreductase activity|regulation of 5,10-CH(2)-H(4)folate reductase activity|regulation of N5,10-methylenetetrahydrofolate reductase activity|regulation of methylenetetrahydrofolate (reduced nicotinamide adenine dinucleotide phosphate) reductase activity|regulation of MTHFR activity|regulation of methylenetetrahydrofolate reductase [NAD(P)H]|regulation of 5-methyltetrahydrofolate:NAD+ oxidoreductase activity|regulation of 5-methyltetrahydrofolate:(acceptor) oxidoreductase activity|regulation of N(5),N(10)-methylenetetrahydrofolate reductase activity|regulation of N5,N10-methylenetetrahydrofolate reductase activity|regulation of 5,10-methylenetetrahydrofolate reductase (NADPH) activity|regulation of 5,10-CH2-H4folate reductase activity|regulation of 5,10-methylenetetrahydrofolate reductase activity|regulation of methylenetetrahydrofolate (reduced riboflavin adenine dinucleotide) reductase activity|regulation of 5-methyltetrahydrofolate:NADP(+) oxidoreductase activity|regulation of 5,10-methylenetetrahydrofolic acid reductase activity|regulation of N(5,10)-methylenetetrahydrofolate reductase activity|regulation of 5,10-methylenetetrahydropteroylglutamate reductase activity|regulation of 5,10-methylenetetrahydrofolate reductase (FADH) activity|regulation of 5,10-methylenetetrahydrofolate reductase (FADH2) activity|regulation of 5-methyltetrahydrofolate:NAD oxidoreductase activity|regulation of MetF							rph	2015-02-05T13:26:14Z					biological_process											owl:Class	
GO:0045542	biolink:NamedThing	positive regulation of cholesterol biosynthetic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cholesterol.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of cholesterol biosynthetic process|upregulation of cholesterol biosynthetic process|positive regulation of cholesterol biosynthesis|positive regulation of cholesterol anabolism|up regulation of cholesterol biosynthetic process|positive regulation of cholesterol formation|activation of cholesterol biosynthetic process|stimulation of cholesterol biosynthetic process|positive regulation of cholesterol synthesis													biological_process											owl:Class	
GO:1901526	biolink:NamedThing	positive regulation of mitophagy	Any process that activates or increases the frequency, rate or extent of mitophagy.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of macromitophagy|upregulation of macromitophagy|positive regulation of macromitophagy|activation of macromitophagy|up regulation of macromitophagy							krc	2012-10-22T16:56:57Z					biological_process											owl:Class	
GO:0099168	biolink:NamedThing	extrinsic component of postsynaptic specialization membrane of symmetric synapse	The component of the postsynaptic specialization membrane of a symmetric synapse consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.	tmpzr1t_l9r_go_relaxed.owl								dos	2017-09-10T12:00:26Z					cellular_component											owl:Class	
GO:1901283	biolink:NamedThing	5,6,7,8-tetrahydromethanopterin metabolic process	The chemical reactions and pathways involving 5,6,7,8-tetrahydromethanopterin.	tmpzr1t_l9r_go_relaxed.owl	5,6,7,8-tetrahydromethanopterin metabolism							yaf	2012-08-17T15:32:33Z					biological_process											owl:Class	
GO:2001117	biolink:NamedThing	tetrahydromethanopterin metabolic process	The chemical reactions and pathways involving a tetrahydromethanopterin.	tmpzr1t_l9r_go_relaxed.owl	tetrahydromethanopterin metabolism							jl	2011-10-11T12:13:15Z					biological_process											owl:Class	
GO:0050070	biolink:NamedThing	lysolecithin acylmutase activity	Catalysis of the reaction: 1-acyl-sn-glycero-3-phosphocholine = 2-acyl-sn-glycero-3-phosphocholine.	tmpzr1t_l9r_go_relaxed.owl	lysolecithin migratase activity|lysolecithin 2,3-acylmutase activity				EC:5.4.1.1|KEGG_REACTION:R03334|MetaCyc:LYSOLECITHIN-ACYLMUTASE-RXN|RHEA:24356									molecular_function											owl:Class	
GO:0106289	biolink:NamedThing	negative regulation of deadenylation-dependent decapping of nuclear-transcribed mRNA	Any process that stops, prevents, or reduces the frequency, rate or extent of deadenylation-dependent decapping of nuclear-transcribed mRNA.	tmpzr1t_l9r_go_relaxed.owl								hjd	2020-08-13T17:12:33Z					biological_process											owl:Class	
GO:0045489	biolink:NamedThing	pectin biosynthetic process	The chemical reactions and pathways resulting in the formation of pectin, a polymer containing a backbone of alpha-1,4-linked D-galacturonic acid residues.	tmpzr1t_l9r_go_relaxed.owl	pectin biosynthesis|pectin formation|pectin anabolism|pectin synthesis													biological_process											owl:Class	
GO:0000271	biolink:NamedThing	polysaccharide biosynthetic process	The chemical reactions and pathways resulting in the formation of a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically.	tmpzr1t_l9r_go_relaxed.owl	polysaccharide synthesis|glycan biosynthetic process|polysaccharide biosynthesis|polysaccharide anabolism|glycan biosynthesis|polysaccharide formation													biological_process											owl:Class	
GO:1903489	biolink:NamedThing	positive regulation of lactation	Any process that activates or increases the frequency, rate or extent of lactation.	tmpzr1t_l9r_go_relaxed.owl	activation of lactation|up-regulation of lactation|up regulation of lactation|upregulation of lactation							mr	2014-09-24T14:44:30Z					biological_process											owl:Class	
GO:0051047	biolink:NamedThing	positive regulation of secretion	Any process that activates or increases the frequency, rate or extent of the controlled release of a substance from a cell or a tissue.	tmpzr1t_l9r_go_relaxed.owl	stimulation of secretion|up-regulation of secretion|up regulation of secretion|upregulation of secretion|activation of secretion													biological_process											owl:Class	
GO:1904509	biolink:NamedThing	negative regulation of protein localization to basolateral plasma membrane	Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to basolateral plasma membrane.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of protein localisation in basolateral plasma membrane|inhibition of protein localization to basolateral plasma membrane|downregulation of protein localisation in basolateral plasma membrane|down-regulation of protein localization in basolateral plasma membrane|negative regulation of protein localization in basolateral plasma membrane|down regulation of protein localisation to basolateral plasma membrane|down-regulation of protein localization to basolateral plasma membrane|down-regulation of protein localisation to basolateral plasma membrane|downregulation of protein localization to basolateral plasma membrane|down regulation of protein localization to basolateral plasma membrane|downregulation of protein localization in basolateral plasma membrane|down regulation of protein localisation in basolateral plasma membrane|down regulation of protein localization in basolateral plasma membrane|inhibition of protein localisation in basolateral plasma membrane|negative regulation of protein localisation in basolateral plasma membrane|negative regulation of protein localisation to basolateral plasma membrane|downregulation of protein localisation to basolateral plasma membrane|inhibition of protein localization in basolateral plasma membrane|inhibition of protein localisation to basolateral plasma membrane							kmv	2015-07-24T17:56:32Z					biological_process											owl:Class	
GO:0015095	biolink:NamedThing	magnesium ion transmembrane transporter activity	Enables the transfer of magnesium (Mg) ions from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-442661|Reactome:R-HSA-5339538|Reactome:R-HSA-5336466|Reactome:R-HSA-5339528|Reactome:R-HSA-5336454|RHEA:29827|Reactome:R-HSA-5336453									molecular_function											owl:Class	
GO:0007079	biolink:NamedThing	mitotic chromosome movement towards spindle pole	The cell cycle process in which the directed movement of chromosomes from the center of the spindle towards the spindle poles occurs. This mediates by the shortening of microtubules attached to the chromosomes, during mitosis.	tmpzr1t_l9r_go_relaxed.owl	chromosome movement towards spindle pole during mitosis|chromosome migration to spindle pole during mitosis|mitotic chromosome movement|mitotic sister chromosome movement towards spindle pole|sister chromosome movement towards spindle pole during mitosis|mitotic chromosome movement to spindle pole											GO:0007082		biological_process											owl:Class	
GO:0051305	biolink:NamedThing	chromosome movement towards spindle pole	The directed movement of chromosomes in the center of the spindle towards the spindle poles, mediated by the shortening of microtubules attached to the chromosomes.	tmpzr1t_l9r_go_relaxed.owl	chromosome migration to spindle pole|chromosome movement to spindle pole|chromosome movement													biological_process											owl:Class	
GO:0031492	biolink:NamedThing	nucleosomal DNA binding	Binding to the DNA portion of a nucleosome.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0031491	biolink:NamedThing	nucleosome binding	Binding to a nucleosome, a complex comprised of DNA wound around a multisubunit core and associated proteins, which forms the primary packing unit of DNA into higher order structures.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0047277	biolink:NamedThing	globoside alpha-N-acetylgalactosaminyltransferase activity	Catalysis of the reaction: N-acetyl-D-galactosaminyl-(1,3)-D-galactosyl-(1,4)-D-galactosyl-(1,4)-D-glucosylceramide + UDP-N-acetylgalactosamine = N-acetyl-D-galactosaminyl-N-acetyl-D-galactosaminyl-(1,3)-D-galactosyl-(1,4)-D-galactosyl-(1,4)-D-glucosylceramide + UDP.	tmpzr1t_l9r_go_relaxed.owl	UDP-N-acetyl-D-galactosamine:N-acetyl-D-galactosaminyl-1,3-D-galactosyl-1,4-D-galactosyl-1,4-D-glucosylceramide alpha-N-acetyl-D-galactosaminyltransferase activity|Forssman synthase activity|uridine diphosphoacetylgalactosamine-globoside alpha-acetylgalactosaminyltransferase activity|globoside acetylgalactosaminyltransferase activity				EC:2.4.1.88|RHEA:22164|MetaCyc:2.4.1.88-RXN									molecular_function											owl:Class	
GO:0050095	biolink:NamedThing	methionine decarboxylase activity	Catalysis of the reaction: L-methionine + H(+) = 3-methylthiopropanamine + CO(2).	tmpzr1t_l9r_go_relaxed.owl	L-methionine carboxy-lyase activity|L-methionine carboxy-lyase (3-methylthiopropanamine-forming)|L-methionine decarboxylase activity				MetaCyc:METHIONINE-DECARBOXYLASE-RXN|KEGG_REACTION:R00656|EC:4.1.1.57|RHEA:17757									molecular_function											owl:Class	
GO:1903637	biolink:NamedThing	negative regulation of protein insertion into mitochondrial outer membrane	Any process that stops, prevents or reduces the frequency, rate or extent of protein insertion into mitochondrial outer membrane.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of mitochondrial outer membrane protein import|down-regulation of protein import into mitochondrial outer membrane|down regulation of protein import into mitochondrial outer membrane|inhibition of mitochondrial outer membrane protein import|down-regulation of protein insertion into mitochondrial outer membrane|downregulation of protein import into mitochondrial outer membrane|downregulation of protein transport into mitochondrial outer membrane|inhibition of protein import into mitochondrial outer membrane|down-regulation of protein transport into mitochondrial outer membrane|inhibition of protein insertion into mitochondrial outer membrane|inhibition of protein transport into mitochondrial outer membrane|down regulation of mitochondrial outer membrane protein import|down regulation of protein insertion into mitochondrial outer membrane|down-regulation of mitochondrial outer membrane protein import|down regulation of protein transport into mitochondrial outer membrane|downregulation of protein insertion into mitochondrial outer membrane|downregulation of mitochondrial outer membrane protein import|negative regulation of protein import into mitochondrial outer membrane|negative regulation of protein transport into mitochondrial outer membrane							pga	2014-11-20T15:54:53Z					biological_process											owl:Class	
GO:0010823	biolink:NamedThing	negative regulation of mitochondrion organization	Any process that decreases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a mitochondrion.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of mitochondrion organisation													biological_process											owl:Class	
GO:0030653	biolink:NamedThing	beta-lactam antibiotic metabolic process	The chemical reactions and pathways involving a beta-lactam antibiotic, any member of a class of natural or semisynthetic antibiotics whose characteristic feature is a strained, four-membered beta-lactam ring. They include the penicillins and many of the cephalosporins.	tmpzr1t_l9r_go_relaxed.owl	beta-lactam antibiotic metabolism													biological_process											owl:Class	
GO:0003099	biolink:NamedThing	positive regulation of the force of heart contraction by chemical signal	Any process which increases the force of heart muscle contraction mediated by chemical signaling, hormonal, autocrine or paracrine.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of the force of heart muscle contraction by chemical signal													biological_process											owl:Class	
GO:0071109	biolink:NamedThing	superior temporal gyrus development	The process whose specific outcome is the progression of the superior temporal gyrus over time, from its formation to the mature structure. The superior temporal gyrus is a portion of the cerebral cortex that extends from the lateral sulcus to the superior temporal sulcus.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-11-12T02:19:23Z					biological_process											owl:Class	
GO:0035541	biolink:NamedThing	negative regulation of SNARE complex disassembly	Any process that decreases the frequency, rate or extent of disassembly of the SNARE complex. The SNARE complex is a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers.	tmpzr1t_l9r_go_relaxed.owl								bf	2010-05-10T01:42:47Z					biological_process											owl:Class	
GO:0045928	biolink:NamedThing	negative regulation of juvenile hormone metabolic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving juvenile hormone.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of juvenile hormone metabolic process|down regulation of juvenile hormone metabolic process|downregulation of juvenile hormone metabolic process|inhibition of juvenile hormone metabolic process|negative regulation of juvenile hormone metabolism													biological_process											owl:Class	
GO:0097448	biolink:NamedThing	spine mat	A configuration of neuron spines found on ciliary ganglion neurons in the embryonic and adult brain consisting of patches of closely spaced spines lying flat against the soma.	tmpzr1t_l9r_go_relaxed.owl					NIF_Subcellular:sao2128156969			pr	2012-12-17T12:34:16Z					cellular_component											owl:Class	
GO:1900090	biolink:NamedThing	positive regulation of inositol biosynthetic process	Any process that activates or increases the frequency, rate or extent of inositol biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	activation of vitamin Bh biosynthetic process|positive regulation of inositol synthesis|activation of inositol formation|up regulation of vitamin Bh biosynthesis|activation of myo-inositol biosynthesis|activation of inositol anabolism|upregulation of myo-inositol biosynthetic process|up-regulation of myo-inositol biosynthetic process|up-regulation of inositol formation|up-regulation of vitamin Bh biosynthetic process|activation of inositol biosynthetic process|positive regulation of vitamin Bh biosynthesis|up regulation of vitamin Bh biosynthetic process|up regulation of inositol biosynthetic process|up regulation of inositol anabolism|upregulation of inositol biosynthetic process|up-regulation of inositol biosynthesis|upregulation of inositol synthesis|upregulation of vitamin Bh biosynthetic process|up regulation of inositol biosynthesis|positive regulation of vitamin Bh biosynthetic process|positive regulation of inositol formation|activation of myo-inositol biosynthetic process|up regulation of myo-inositol biosynthetic process|activation of inositol synthesis|up-regulation of myo-inositol biosynthesis|upregulation of inositol anabolism|up-regulation of inositol anabolism|up-regulation of vitamin Bh biosynthesis|positive regulation of inositol anabolism|up regulation of inositol formation|upregulation of inositol biosynthesis|upregulation of vitamin Bh biosynthesis|upregulation of inositol formation|upregulation of myo-inositol biosynthesis|up-regulation of inositol biosynthetic process|positive regulation of inositol biosynthesis|up regulation of inositol synthesis|activation of vitamin Bh biosynthesis|positive regulation of myo-inositol biosynthesis|up regulation of myo-inositol biosynthesis|activation of inositol biosynthesis|up-regulation of inositol synthesis|positive regulation of myo-inositol biosynthetic process							dhl	2012-02-08T06:27:31Z					biological_process											owl:Class	
GO:0030071	biolink:NamedThing	regulation of mitotic metaphase/anaphase transition	Any process that modulates the frequency, rate or extent of the cell cycle process in which a cell progresses from metaphase to anaphase during mitosis, triggered by the activation of the anaphase promoting complex by Cdc20/Sleepy homolog which results in the degradation of Securin.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0010760	biolink:NamedThing	negative regulation of macrophage chemotaxis	Any process that decreases the rate, frequency or extent of macrophage chemotaxis. Macrophage chemotaxis is the movement of a macrophage in response to an external stimulus.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0010758	biolink:NamedThing	regulation of macrophage chemotaxis	Any process that modulates the rate, frequency or extent of macrophage chemotaxis. Macrophage chemotaxis is the movement of a macrophage in response to an external stimulus.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0043648	biolink:NamedThing	dicarboxylic acid metabolic process	The chemical reactions and pathways involving dicarboxylic acids, any organic acid containing two carboxyl (COOH) groups or anions (COO-).	tmpzr1t_l9r_go_relaxed.owl	dicarboxylate metabolic process|dicarboxylic acid metabolism|dicarboxylate metabolism													biological_process											owl:Class	
GO:0047503	biolink:NamedThing	(-)-borneol dehydrogenase activity	Catalysis of the reaction: (-)-borneol + NAD(+) = (1S,4S)-camphor + H(+) + NADH.	tmpzr1t_l9r_go_relaxed.owl	(-)-borneol:NAD+ oxidoreductase activity				KEGG_REACTION:R02945|EC:1.1.1.227|MetaCyc:--BORNEOL-DEHYDROGENASE-RXN|RHEA:22128									molecular_function											owl:Class	
GO:0047749	biolink:NamedThing	cholestanetriol 26-monooxygenase activity	Catalysis of the reaction: 5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol + NADPH + O2 = 5-beta-cholestane-3-alpha,7-alpha,12-alpha,26-tetraol + NADP+ + H2O.	tmpzr1t_l9r_go_relaxed.owl	cholestanetriol 26-hydroxylase activity|CYP27A1|5beta-cholestane-3alpha,7alpha,12alpha-triol hydroxylase activity|cholesterol 27-hydroxylase activity|CYP27A|sterol 27-hydroxylase activity|5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol hydroxylase activity|5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol 26-hydroxylase activity|5beta-cholestane-3alpha,7alpha,12alpha-triol,NADPH:oxygen oxidoreductase (26-hydroxylating)|cytochrome P450 27A1' activity|sterol 26-hydroxylase activity|5beta-cholestane-3alpha,7alpha,12alpha-triol 26-hydroxylase activity				EC:1.14.15.15|RHEA:14373|MetaCyc:CHOLESTANETRIOL-26-MONOOXYGENASE-RXN									molecular_function											owl:Class	
GO:0061499	biolink:NamedThing	outer plaque of mitotic spindle pole body	One of three laminate structures that form the mitotic spindle pole body; the outer plaque is in the cytoplasm.	tmpzr1t_l9r_go_relaxed.owl								dph	2012-12-11T09:18:43Z					cellular_component											owl:Class	
GO:0005824	biolink:NamedThing	outer plaque of spindle pole body	One of three laminate structures that form the spindle pole body; the outer plaque is in the cytoplasm.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0009927	biolink:NamedThing	histidine phosphotransfer kinase activity	Serves as a phospho-His intermediate enabling the transfer of phospho group between a hybrid kinase and a response regulator.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/15611												molecular_function											owl:Class	
GO:0060089	biolink:NamedThing	molecular transducer activity	A compound molecular function in which an effector function is controlled by one or more regulatory components.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0099130	biolink:NamedThing	estrogen binding	Binding to an estrogen.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0042562	biolink:NamedThing	hormone binding	Binding to an hormone, a naturally occurring substance secreted by specialized cells that affect the metabolism or behavior of cells possessing functional receptors for the hormone. Hormones may be produced by the same, or different, cell as express the receptor.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1902820	biolink:NamedThing	1-undecene metabolic process	The chemical reactions and pathways involving 1-undecene.	tmpzr1t_l9r_go_relaxed.owl	1-undecene metabolism							tt	2014-03-31T02:50:48Z					biological_process											owl:Class	
GO:2000890	biolink:NamedThing	cellodextrin catabolic process	The chemical reactions and pathways resulting in the breakdown of a cellodextrin.	tmpzr1t_l9r_go_relaxed.owl	cellodextrin catabolism							jl	2011-07-28T01:05:21Z					biological_process											owl:Class	
GO:0043022	biolink:NamedThing	ribosome binding	Binding to a ribosome.	tmpzr1t_l9r_go_relaxed.owl	ribosome receptor activity											GO:0030376		molecular_function											owl:Class	
GO:0021954	biolink:NamedThing	central nervous system neuron development	The process whose specific outcome is the progression of a neuron whose cell body is located in the central nervous system, from initial commitment of the cell to a neuronal fate, to the fully functional differentiated neuron.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0048666	biolink:NamedThing	neuron development	The process whose specific outcome is the progression of a neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0090589	biolink:NamedThing	protein-phosphocysteine-trehalose phosphotransferase system transporter activity	Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein S-phosphocysteine + trehalose (out) = protein cysteine + trehalose-6-phosphate (in).	tmpzr1t_l9r_go_relaxed.owl								tb	2014-06-04T16:22:31Z					molecular_function											owl:Class	
GO:0090118	biolink:NamedThing	receptor-mediated endocytosis involved in cholesterol transport	A receptor-mediated endocytosis process involved in intracellular cholesterol transport.	tmpzr1t_l9r_go_relaxed.owl	receptor-mediated endocytosis involved in intracellular cholesterol transport|receptor-mediated endocytosis of LDL|receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport|receptor-mediated endocytosis of low-density lipoprotein involved in cholesterol transport							tb	2009-12-07T12:06:05Z					biological_process											owl:Class	
GO:2000510	biolink:NamedThing	positive regulation of dendritic cell chemotaxis	Any process that activates or increases the frequency, rate or extent of dendritic cell chemotaxis.	tmpzr1t_l9r_go_relaxed.owl								ebc	2011-03-22T10:21:49Z					biological_process											owl:Class	
GO:0035621	biolink:NamedThing	ER to Golgi ceramide transport	The directed movement of a ceramide from the endoplasmic reticulum (ER) to the Golgi. Ceramides are a class of lipid composed of sphingosine linked to a fatty acid.	tmpzr1t_l9r_go_relaxed.owl	ER to Golgi ceramide translocation|non-vesicular ceramide trafficking|endoplasmic reticulum to Golgi ceramide transport							bf	2010-12-08T12:36:35Z					biological_process											owl:Class	
GO:0032365	biolink:NamedThing	intracellular lipid transport	The directed movement of lipids within cells.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0120161	biolink:NamedThing	regulation of cold-induced thermogenesis	Any process that modulates the frequency, rate or extent of cold-induced thermogenesis.	tmpzr1t_l9r_go_relaxed.owl	regulation of CIT							krc	2018-05-14T17:03:19Z					biological_process											owl:Class	
GO:0072041	biolink:NamedThing	positive regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis	Any process that increases the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of mesenchymal stem cell apoptosis involved in nephron morphogenesis|positive regulation of mesenchymal stem cell apoptotic process involved in nephron morphogenesis							mah	2010-01-25T03:10:32Z					biological_process											owl:Class	
GO:2001055	biolink:NamedThing	positive regulation of mesenchymal cell apoptotic process	Any process that activates or increases the frequency, rate or extent of mesenchymal cell apoptotic process.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of mesenchymal cell apoptosis							yaf	2011-09-08T02:50:09Z					biological_process											owl:Class	
GO:1903873	biolink:NamedThing	negative regulation of DNA recombinase mediator complex assembly	Any process that stops, prevents or reduces the frequency, rate or extent of DNA recombinase mediator complex assembly.	tmpzr1t_l9r_go_relaxed.owl	inhibition of DNA recombinase mediator complex assembly|inhibition of DNA recombinase mediator complex formation|downregulation of DNA recombinase mediator complex formation|down regulation of DNA recombinase mediator complex assembly|down-regulation of DNA recombinase mediator complex assembly|down regulation of DNA recombinase mediator complex formation|downregulation of DNA recombinase mediator complex assembly|negative regulation of DNA recombinase mediator complex formation|down-regulation of DNA recombinase mediator complex formation							rb	2015-02-05T23:36:54Z					biological_process											owl:Class	
GO:0009361	biolink:NamedThing	succinate-CoA ligase complex (ADP-forming)	A heterodimeric enzyme complex, composed of an alpha and beta chain, most usually found in (but not limited to) bacteria. Functions in the TCA cycle, hydrolyzing succinyl-CoA into succinate and CoA, thereby forming ATP.	tmpzr1t_l9r_go_relaxed.owl	succinyl-CoA synthetase, ADP-forming													cellular_component											owl:Class	
GO:0042709	biolink:NamedThing	succinate-CoA ligase complex	A heterodimeric enzyme complex, usually composed of an alpha and beta chain. Functions in the TCA cycle, hydrolyzing succinyl-CoA into succinate and CoA, thereby forming ATP or GTP.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0032714	biolink:NamedThing	negative regulation of interleukin-5 production	Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-5 production.	tmpzr1t_l9r_go_relaxed.owl	down regulation of interleukin-5 production|negative regulation of interleukin-5 biosynthetic process|inhibition of interleukin-5 production|down-regulation of interleukin-5 production|negative regulation of IL-5 production|negative regulation of interleukin-5 secretion|downregulation of interleukin-5 production											GO:2000663|GO:0045406		biological_process											owl:Class	
GO:0032674	biolink:NamedThing	regulation of interleukin-5 production	Any process that modulates the frequency, rate, or extent of interleukin-5 production.	tmpzr1t_l9r_go_relaxed.owl	regulation of IL-5 production|regulation of interleukin-5 biosynthetic process|regulation of interleukin-5 secretion											GO:0045405|GO:2000662		biological_process											owl:Class	
GO:0032843	biolink:NamedThing	hydroperoxide reductase activity	Catalysis of the reaction: 2 RSH + ROOH = RSSR + ROH + H2O. This reaction is the thiol-dependent conversion of an organic hydroperoxide to the corresponding alcohol.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0019144	biolink:NamedThing	ADP-sugar diphosphatase activity	Catalysis of the reaction: ADP-sugar + H2O = AMP + sugar 1-phosphate.	tmpzr1t_l9r_go_relaxed.owl	nucleoside diphosphate-sugar hydrolase activity|ADP-sugar sugarphosphohydrolase activity|adenosine diphosphosugar pyrophosphatase activity|ADP-sugar pyrophosphatase activity|ADPsugar pyrophosphatase activity				MetaCyc:ADPSUGPPHOSPHAT-RXN|EC:3.6.1.21									molecular_function											owl:Class	
GO:0047064	biolink:NamedThing	sulochrin oxidase [(+)-bisdechlorogeodin-forming] activity	Catalysis of the reaction: O(2) + 2 sulochrin = 2 (2S)-bisdechlorogeodin + 2 H(2)O.	tmpzr1t_l9r_go_relaxed.owl	sulochrin:oxygen oxidoreductase (cyclizing, (+)-specific)|sulochrin oxidase activity				EC:1.21.3.4|MetaCyc:1.10.3.7-RXN|KEGG_REACTION:R00060|RHEA:24092									molecular_function											owl:Class	
GO:0051367	biolink:NamedThing	peptidyl-serine decanoylation	The decanoylation of peptidyl-serine to form peptidyl-O3-decanoyl-L-serine, typical of the protein ghrelin.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0385									biological_process											owl:Class	
GO:0051366	biolink:NamedThing	protein decanoylation	The modification of a protein amino acid by formation of an ester or amide with decanoic acid.	tmpzr1t_l9r_go_relaxed.owl	protein amino acid decanoylation													biological_process											owl:Class	
GO:0033411	biolink:NamedThing	UAA codon-amino acid adaptor activity	A triplet codon-amino acid adaptor activity that recognizes a UAA codon.	tmpzr1t_l9r_go_relaxed.owl	TAA codon-amino acid adaptor activity					Note that in the standard genetic code, TAA is a stop codon (ochre) and is not normally read by a tRNA.								molecular_function											owl:Class	
GO:1902423	biolink:NamedThing	regulation of attachment of mitotic spindle microtubules to kinetochore	Any process that modulates the frequency, rate or extent of attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation.	tmpzr1t_l9r_go_relaxed.owl	regulation of attachment of spindle microtubules to kinetochore during mitosis|regulation of attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation|regulation of mitotic attachment of spindle microtubules to kinetochore|regulation of mitotic bipolar attachment|regulation of attachment of spindle microtubules to mitotic chromosome|regulation of attachment of spindle microtubules to kinetochore involved in mitosis							vw	2013-09-19T10:33:38Z					biological_process											owl:Class	
GO:0033047	biolink:NamedThing	regulation of mitotic sister chromatid segregation	Any process that modulates the frequency, rate or extent of sister chromatid segregation during mitosis.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0030166	biolink:NamedThing	proteoglycan biosynthetic process	The chemical reactions and pathways resulting in the formation of proteoglycans, any glycoprotein in which the carbohydrate units are glycosaminoglycans.	tmpzr1t_l9r_go_relaxed.owl	proteoglycan formation|proteoglycan anabolism|proteoglycan synthesis|proteoglycan biosynthesis													biological_process											owl:Class	
GO:0032897	biolink:NamedThing	negative regulation of viral transcription	Any process that stops, prevents, or reduces the frequency, rate or extent of viral transcription.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of viral transcription|inhibition of viral transcription|downregulation of viral transcription|down regulation of viral transcription													biological_process											owl:Class	
GO:0046168	biolink:NamedThing	glycerol-3-phosphate catabolic process	The chemical reactions and pathways resulting in the breakdown of glycerol-3-phosphate, a phosphoric monoester of glycerol.	tmpzr1t_l9r_go_relaxed.owl	glycerol-3-phosphate catabolism|glycerol-3-phosphate degradation|glycerol-3-phosphate breakdown													biological_process											owl:Class	
GO:0140543	biolink:NamedThing	positive regulation of piRNA transcription	Any process that increases the frequency, rate or extent of the synthesis of piRNA.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/19530						pg	2020-11-09T19:26:02Z					biological_process											owl:Class	
GO:0140542	biolink:NamedThing	regulation of piRNA transcription	Any process that modulates the frequency, rate or extent of the synthesis of a piRNA.	tmpzr1t_l9r_go_relaxed.owl								pg	2020-11-09T19:08:15Z					biological_process											owl:Class	
GO:0080062	biolink:NamedThing	cytokinin 9-beta-glucosyltransferase activity	Catalysis of the reaction: 6-alkylaminopurine + UDP-D-glucose = 6-alkylamino-9-beta-D-glucosylpurine + H+ + UDP. This reaction is an N-glucosylation event.	tmpzr1t_l9r_go_relaxed.owl					KEGG_REACTION:R08369			dhl	2009-04-13T03:34:38Z					molecular_function											owl:Class	
GO:0140717	biolink:NamedThing	entry into host through the stromata	Entry of a symbiont into host plant tissue via the stromata, microscopic pores in the epidermis of the aerial parts of terrestrial plants. These pores are essential for photosynthesis, as they allow CO(2) to diffuse into the plant. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/22206						pg	2021-09-27T16:30:08Z					biological_process											owl:Class	
GO:0044409	biolink:NamedThing	entry into host	Entry of a symbiont into the body, tissues, or cells of a host organism as part of the symbiont life cycle. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	entry into other organism during symbiotic interaction|entry into host cell|penetration into host via a specialized structure|penetration into host via a specialized structure during symbiotic interaction|entry into cell of other organism involved in symbiotic interaction|host cell invasion|entry into cell of other organism during symbiotic interaction|entry into host via a specialized structure during symbiotic interaction|invasion into other organism|entry into host via enzymatic degradation of host cuticle|penetration into host|invasion of host|host penetration|invasion of other organism|invasion into host|entry into host cell via penetration peg|invasive growth|entry into other organism involved in symbiotic interaction|host invasion|entry into host via enzymatic degradation of host anatomical structure|other organism cell invasion|other organism invasion|entry into host through host barriers	https://github.com/geneontology/go-ontology/issues/18563										GO:0044411|GO:0051830|GO:0051828|GO:0085027|GO:0085028|GO:0075052|GO:0051806|GO:0030260		biological_process											owl:Class	
GO:0032086	biolink:NamedThing	regulation of type III site-specific deoxyribonuclease activity	Any process that modulates the frequency, rate or extent of a type III restriction endodeoxyribonuclease activity.	tmpzr1t_l9r_go_relaxed.owl	type III restriction endodeoxyribonuclease regulator|regulation of type III restriction endoribonuclease activity|type III restriction enzyme regulator													biological_process											owl:Class	
GO:1903663	biolink:NamedThing	L-altrarate catabolic process	The chemical reactions and pathways resulting in the breakdown of L-altrarate.	tmpzr1t_l9r_go_relaxed.owl	L-altrarate(1-) catabolism|L-altrarate(1-) breakdown|L-altrarate(1-) degradation							jl	2014-11-26T14:34:28Z					biological_process											owl:Class	
GO:2000979	biolink:NamedThing	positive regulation of forebrain neuron differentiation	Any process that activates or increases the frequency, rate or extent of forebrain neuron differentiation.	tmpzr1t_l9r_go_relaxed.owl								yaf	2011-08-03T12:09:19Z					biological_process											owl:Class	
GO:2000977	biolink:NamedThing	regulation of forebrain neuron differentiation	Any process that modulates the frequency, rate or extent of forebrain neuron differentiation.	tmpzr1t_l9r_go_relaxed.owl								yaf	2011-08-03T12:09:12Z					biological_process											owl:Class	
GO:0097119	biolink:NamedThing	postsynaptic density protein 95 clustering	The clustering process in which postsynaptic density protein 95 (PSD-95) molecules are localized to distinct domains in the cell membrane. PSD-95 is mostly located in the post synaptic density of neurons, and is involved in anchoring synaptic proteins.	tmpzr1t_l9r_go_relaxed.owl	Dlg4 clustering|PSD-95 clustering|post-synaptic density protein 95 clustering							pr	2011-07-31T05:49:44Z					biological_process											owl:Class	
GO:0072657	biolink:NamedThing	protein localization to membrane	A process in which a protein is transported to, or maintained in, a specific location in a membrane.	tmpzr1t_l9r_go_relaxed.owl	protein localisation in membrane|protein localization in membrane							mah	2011-02-14T02:35:18Z					biological_process											owl:Class	
GO:0106248	biolink:NamedThing	positive regulation of poly(A)-specific ribonuclease activity	Any process that activates or increases the frequency, rate or extent of poly(A)-specific ribonuclease activity.	tmpzr1t_l9r_go_relaxed.owl								hjd	2020-02-03T19:04:00Z					biological_process											owl:Class	
GO:0106246	biolink:NamedThing	regulation of poly(A)-specific ribonuclease activity	Any process that modulates the rate, frequency or extent of the catalysis of the exonucleolytic cleavage of poly(A) to 5'-AMP.	tmpzr1t_l9r_go_relaxed.owl								hjd	2020-02-03T18:56:03Z					biological_process											owl:Class	
GO:0021859	biolink:NamedThing	pyramidal neuron differentiation	The process in which a neuroblast or one of its progeny commits to a pyramidal neuron fate, migrates from the ventricular zone to the appropriate layer in the cortex and develops into a mature neuron.	tmpzr1t_l9r_go_relaxed.owl	projection neuron differentiation													biological_process											owl:Class	
GO:0030182	biolink:NamedThing	neuron differentiation	The process in which a relatively unspecialized cell acquires specialized features of a neuron.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0102478	biolink:NamedThing	beta-L-arabinofuranosidase activity	Catalysis of the reaction: beta-L-arabinofuranosyl-(1->2)-beta-L-arabinofuranose + H2O = 2 beta-L-arabinofuranose.	tmpzr1t_l9r_go_relaxed.owl					RHEA:36051|EC:3.2.1.185|MetaCyc:RXN-14089									molecular_function											owl:Class	
GO:1903468	biolink:NamedThing	positive regulation of DNA replication initiation	Any process that activates or increases the frequency, rate or extent of DNA replication initiation involved in mitotic DNA replication.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of DNA replication initiation involved in mitotic cell cycle DNA replication|up regulation of DNA replication initiation involved in mitotic DNA replication|up regulation of DNA replication initiation involved in mitotic cell cycle DNA replication|upregulation of DNA replication initiation involved in mitotic cell cycle DNA replication|upregulation of DNA replication initiation involved in mitotic DNA replication|activation of DNA replication initiation involved in mitotic DNA replication|activation of DNA replication initiation involved in mitotic cell cycle DNA replication|up-regulation of DNA replication initiation involved in mitotic DNA replication|positive regulation of DNA replication initiation involved in mitotic cell cycle DNA replication							vw	2014-09-23T13:39:06Z					biological_process											owl:Class	
GO:0032036	biolink:NamedThing	myosin heavy chain binding	Binding to a heavy chain of a myosin complex.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1905342	biolink:NamedThing	positive regulation of protein localization to kinetochore	Any process that activates or increases the frequency, rate or extent of protein localization to kinetochore.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of condensin localization to kinetochore|activation of protein localization to kinetochore|up regulation of protein localization to kinetochore|upregulation of protein localization to kinetochore|up regulation of condensin localization to kinetochore|upregulation of condensin localization to kinetochore|up-regulation of protein localisation to kinetochore|positive regulation of protein localisation to kinetochore|activation of condensin localization to kinetochore|up regulation of protein localisation to kinetochore|up-regulation of protein localization to kinetochore|upregulation of protein localisation to kinetochore|activation of protein localisation to kinetochore|up-regulation of condensin localization to kinetochore					Q9H211 in Human in PMID:22581055		es	2016-07-27T15:26:51Z					biological_process											owl:Class	
GO:0098898	biolink:NamedThing	dense core granule lumen	The volume enclosed by the dense core granule membrane.	tmpzr1t_l9r_go_relaxed.owl	dense core vesicle lumen													cellular_component											owl:Class	
GO:0072338	biolink:NamedThing	cellular lactam metabolic process	The chemical reactions and pathways involving lactams, any cyclic amides of amino carboxylic acids, having a 1-azacycloalkan-2-one structure, or analogues having unsaturation or heteroatoms replacing one or more carbon atoms of the ring.	tmpzr1t_l9r_go_relaxed.owl	cellular lactam metabolism							mah	2010-11-04T04:31:21Z					biological_process											owl:Class	
GO:0006523	biolink:NamedThing	alanine biosynthetic process	The chemical reactions and pathways resulting in the formation of alanine, 2-aminopropanoic acid.	tmpzr1t_l9r_go_relaxed.owl	alanine biosynthesis|alanine synthesis|alanine anabolism|alanine formation													biological_process											owl:Class	
GO:0031509	biolink:NamedThing	subtelomeric heterochromatin assembly	The assembly of chromatin into heterochromatin at the subtelomeric region, resulting in a chromatin conformation refractory to transcription.	tmpzr1t_l9r_go_relaxed.owl	Telomere Position Effect|heterochromatic silencing at telomere|subtelomere chromatin silencing|subtelomeric silencing|chromatin silencing at subtelomere|regulation of subtelomeric heterochromatin assembly|telomeric heterochromatin formation|telomeric heterochromatin assembly|heterochromatic silencing at subtelomere|establishment of chromatin silencing at telomere|regulation of chromatin silencing at telomere|telomeric silencing|chromatin silencing at telomere|telomere chromatin silencing	https://github.com/geneontology/go-ontology/issues/19308|https://github.com/geneontology/go-ontology/issues/22027|https://github.com/geneontology/go-ontology/issues/19188										GO:0099114|GO:0006348|GO:0035390		biological_process											owl:Class	
GO:0006311	biolink:NamedThing	meiotic gene conversion	The cell cycle process in which genetic information is transferred from one helix to another. It often occurs in association with general genetic recombination events, and is believed to be a straightforward consequence of the mechanisms of general recombination and DNA repair. For example, meiosis might yield three copies of the maternal version of an allele and only one copy of the paternal allele, indicating that one of the two copies of the paternal allele has been changed to a copy of the maternal allele.	tmpzr1t_l9r_go_relaxed.owl	gene conversion without reciprocal crossover													biological_process											owl:Class	
GO:0035822	biolink:NamedThing	gene conversion	A DNA recombination process that results in the unidirectional transfer of genetic material from a donor sequence to a highly homologous acceptor. The resulting acceptor sequence is identical to that of the donor.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/18777						bf	2011-05-04T01:04:39Z					biological_process											owl:Class	
GO:1901764	biolink:NamedThing	phosphinothricin metabolic process	The chemical reactions and pathways involving phosphinothricin.	tmpzr1t_l9r_go_relaxed.owl	phosphinothricin metabolism							yaf	2013-01-15T10:02:37Z					biological_process											owl:Class	
GO:0034823	biolink:NamedThing	citronellyl-CoA ligase activity	Catalysis of the reaction: citronellate + CoASH + ATP = citronellyl-CoA + AMP + PPi.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r1157|KEGG_REACTION:R08088									molecular_function											owl:Class	
GO:0042744	biolink:NamedThing	hydrogen peroxide catabolic process	The chemical reactions and pathways resulting in the breakdown of hydrogen peroxide (H2O2).	tmpzr1t_l9r_go_relaxed.owl	hydrogen peroxide degradation|hydrogen peroxide breakdown|H2O2 catabolic process|H2O2 scavenging|detoxification of hydrogen peroxide|hydrogen peroxide catabolism|hydrogen peroxide scavenging|hydrogen peroxide removal|detoxification of H2O2													biological_process											owl:Class	
GO:0060964	biolink:NamedThing	regulation of gene silencing by miRNA	Any process that modulates the rate, frequency, or extent of the downregulation of gene expression through the action of microRNAs (miRNAs), endogenous 21-24 nucleotide small RNAs processed from stem-loop RNA precursors (pre-miRNAs). Once incorporated into a RNA-induced silencing complex (RISC), miRNAs can downregulate gene expression by either of two posttranscriptional mechanisms: RNA (often mRNA) cleavage or mRNA translational repression.	tmpzr1t_l9r_go_relaxed.owl	regulation of gene silencing by microRNA							dph	2009-10-05T03:10:28Z					biological_process											owl:Class	
GO:1905497	biolink:NamedThing	negative regulation of triplex DNA binding	Any process that stops, prevents or reduces the frequency, rate or extent of triplex DNA binding.	tmpzr1t_l9r_go_relaxed.owl	downregulation of triplex DNA binding|down regulation of triplex DNA binding|down-regulation of triplex DNA binding|inhibition of triplex DNA binding							ans	2016-09-26T14:57:17Z					biological_process											owl:Class	
GO:2000652	biolink:NamedThing	regulation of secondary cell wall biogenesis	Any process that modulates the frequency, rate or extent of secondary cell wall biogenesis.	tmpzr1t_l9r_go_relaxed.owl	regulation of secondary cell wall synthesis|regulation of plant-type secondary cell wall biogenesis|regulation of secondary cell wall anabolism|regulation of secondary cell wall biosynthetic process|regulation of cellulose and pectin-containing secondary cell wall biogenesis|regulation of secondary cell wall formation							dhl	2011-04-29T08:50:02Z					biological_process											owl:Class	
GO:0019351	biolink:NamedThing	dethiobiotin biosynthetic process	The chemical reactions and pathways resulting in the formation of dethiobiotin, a derivative of biotin in which the sulfur atom has been replaced by two hydrogen atoms.	tmpzr1t_l9r_go_relaxed.owl	desthiobiotin biosynthetic process|dethiobiotin biosynthesis|dethiobiotin anabolism|dethiobiotin synthesis|desthiobiotin biosynthesis|dethiobiotin formation													biological_process											owl:Class	
GO:0060882	biolink:NamedThing	basement membrane disassembly involved in semicircular canal fusion	A process that results in the breakdown of the basement membrane that contributes to the process of semicircular canal fusion.	tmpzr1t_l9r_go_relaxed.owl	basal lamina disassembly involved in semicircular canal fusion							dph	2009-08-13T11:29:52Z					biological_process											owl:Class	
GO:0034769	biolink:NamedThing	basement membrane disassembly	The controlled breakdown of the basement membrane in the context of a normal process such as imaginal disc eversion.	tmpzr1t_l9r_go_relaxed.owl	basal lamina disassembly					Note that this term has no relationship to 'membrane disassembly ; GO:0030397' because the basement membrane is not a lipid bilayer.		dph	2009-08-13T11:27:24Z			GO:0060881		biological_process											owl:Class	
GO:0045110	biolink:NamedThing	intermediate filament bundle assembly	The formation of the bundles of intermediate filaments. Intermediate filament-associated proteins (IFAPs) cross-link intermediate filaments with one another, forming a bundle or a network, and with other cell structures, including the plasma membrane. The organization of intermediate filaments and their supportive function in various cells types depends in large part on their linkage to other cell structures via IFAPs.	tmpzr1t_l9r_go_relaxed.owl	tonofilament assembly													biological_process											owl:Class	
GO:0009084	biolink:NamedThing	glutamine family amino acid biosynthetic process	The chemical reactions and pathways resulting in the formation of amino acids of the glutamine family, comprising arginine, glutamate, glutamine and proline.	tmpzr1t_l9r_go_relaxed.owl	glutamine family amino acid biosynthesis|glutamine family amino acid formation|glutamine family amino acid anabolism|glutamine family amino acid synthesis													biological_process											owl:Class	
GO:1901607	biolink:NamedThing	alpha-amino acid biosynthetic process	The chemical reactions and pathways resulting in the formation of an alpha-amino acid.	tmpzr1t_l9r_go_relaxed.owl	alpha-amino acid biosynthesis|alpha-amino acid synthesis|alpha-amino acid formation|alpha-amino acid anabolism							tb	2012-11-08T17:39:58Z					biological_process											owl:Class	
GO:1904174	biolink:NamedThing	negative regulation of histone demethylase activity (H3-K4 specific)	Any process that stops, prevents or reduces the frequency, rate or extent of histone demethylase activity (H3-K4 specific).	tmpzr1t_l9r_go_relaxed.owl	down regulation of histone demethylase activity (H3-K4 specific)|downregulation of histone demethylase activity (H3-K4 specific)|down-regulation of histone demethylase activity (H3-K4 specific)|inhibition of histone demethylase activity (H3-K4 specific)							dph	2015-04-24T19:29:38Z					biological_process											owl:Class	
GO:0031057	biolink:NamedThing	negative regulation of histone modification	Any process that stops, prevents, or reduces the frequency, rate or extent of the covalent alteration of a histone.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of histone modification|downregulation of histone modification|inhibition of histone modification|down regulation of histone modification													biological_process											owl:Class	
GO:0018770	biolink:NamedThing	6-oxo-2-hydroxy-7-(4'-chlorophenyl)-3,8,8-trichloroocta-2E,4E,7-trienoate hydrolase activity	Catalysis of the reaction: 6-oxo-2-hydroxy-7-(4'-chlorophenyl)-3,8,8-trichloroocta-2Z,4Z,7-trienoate + H2O = 2-(4'-chlorophenyl)-3,3-dichloropropenoate + cis-2-Hydroxy-3-chloropenta-2,4-dienone + H+.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0444									molecular_function											owl:Class	
GO:0015192	biolink:NamedThing	L-phenylalanine transmembrane transporter activity	Enables the transfer of L-phenylalanine from one side of a membrane to the other. L-phenylalanine is 2-amino-3-phenylpropanoic acid.	tmpzr1t_l9r_go_relaxed.owl	L-phenylalanine permease activity|L-phenylalanine transporter activity													molecular_function											owl:Class	
GO:0070303	biolink:NamedThing	negative regulation of stress-activated protein kinase signaling cascade	Any process that stops, prevents, or reduces the frequency, rate or extent of signaling via the stress-activated protein kinase signaling cascade.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of stress-activated protein kinase signaling pathway|negative regulation of stress-activated protein kinase signalling pathway|down regulation of stress-activated protein kinase signaling pathway|downregulation of stress-activated protein kinase signaling pathway|negative regulation of SAPK signaling pathway|down-regulation of stress-activated protein kinase signaling pathway|inhibition of stress-activated protein kinase signaling pathway													biological_process											owl:Class	
GO:0050540	biolink:NamedThing	2-aminomuconate deaminase activity	Catalysis of the reaction: 2-aminomuconate + H(2)O + H(+) = (Z)-5-oxohex-2-enedioate + NH(4)(+).	tmpzr1t_l9r_go_relaxed.owl	2-aminomuconate aminohydrolase activity				KEGG_REACTION:R03887|MetaCyc:3.5.99.5-RXN|RHEA:20996|EC:3.5.99.5									molecular_function											owl:Class	
GO:0010547	biolink:NamedThing	thylakoid membrane disassembly	The controlled breakdown of the thylakoid membrane in the context of a normal process.	tmpzr1t_l9r_go_relaxed.owl	thylakoid membrane degradation													biological_process											owl:Class	
GO:0010027	biolink:NamedThing	thylakoid membrane organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the thylakoid membrane.	tmpzr1t_l9r_go_relaxed.owl	thylakoid membrane organization and biogenesis|thylakoid membrane organisation					See also the cellular component term 'thylakoid membrane ; GO:0042651'.								biological_process											owl:Class	
GO:1905701	biolink:NamedThing	positive regulation of xenobiotic detoxification by transmembrane export across the plasma membrane	Any process that activates or increases the frequency, rate or extent of xenobiotic transmembrane export. A xenobiotic is a compound foreign to the organim exposed to it. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of drug transmembrane export|positive regulation of xenobiotic transmembrane export|activation of drug transmembrane export|positive regulation of drug transmembrane export|up regulation of drug transmembrane export|upregulation of drug transmembrane export	https://github.com/geneontology/go-ontology/issues/19460|https://github.com/geneontology/go-ontology/issues/17083						sl	2016-11-15T16:46:44Z					biological_process											owl:Class	
GO:0019094	biolink:NamedThing	pole plasm mRNA localization	Any process in which mRNA is transported to, or maintained in, the oocyte pole plasm. An example of this is found in Drosophila melanogaster.	tmpzr1t_l9r_go_relaxed.owl	establishment and maintenance of pole plasm mRNA localization|pole plasm mRNA localisation|establishment and maintenance of mRNA localization in pole plasm|pole granule RNA localization|oocyte pole plasm mRNA localization											GO:0048120		biological_process											owl:Class	
GO:0047940	biolink:NamedThing	glucuronokinase activity	Catalysis of the reaction: D-glucuronate + ATP = 1-phospho-alpha-D-glucuronate + ADP + 2 H(+).	tmpzr1t_l9r_go_relaxed.owl	ATP:D-glucuronate 1-phosphotransferase activity|glucuronokinase (phosphorylating)|glucurono-glucuronokinase activity				MetaCyc:GLUCURONOKINASE-RXN|KEGG_REACTION:R01476|EC:2.7.1.43|RHEA:17005									molecular_function											owl:Class	
GO:0038047	biolink:NamedThing	morphine receptor activity	Combining with morphine (17-methyl-7,8-didehydro-4,5alpha-epoxymorphinan-3,6alpha-diol), and transmitting the signal across the membrane by activating an associated G-protein.	tmpzr1t_l9r_go_relaxed.owl	mu-opioid receptor activity							bf	2011-11-14T01:35:18Z					molecular_function											owl:Class	
GO:0004985	biolink:NamedThing	G protein-coupled opioid receptor activity	Combining with an opioid (any narcotic derived from or resembling opium), and transmitting the signal across the membrane by activating an associated G-protein.	tmpzr1t_l9r_go_relaxed.owl	opioid receptor activity	https://github.com/geneontology/go-ontology/issues/21110												molecular_function											owl:Class	
GO:1900680	biolink:NamedThing	positive regulation of ferricrocin biosynthetic process	Any process that activates or increases the frequency, rate or extent of ferricrocin biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	upregulation of ferricrocin biosynthetic process, peptide modification|positive regulation of ferricrocin formation|up regulation of ferricrocin biosynthetic process, peptide modification|upregulation of ferricrocin biosynthetic process, peptide formation|positive regulation of ferricrocin biosynthesis|upregulation of ferricrocin anabolism|up regulation of ferricrocin formation|up-regulation of ferricrocin anabolism|positive regulation of ferricrocin biosynthetic process, peptide formation|activation of ferricrocin biosynthesis|activation of ferricrocin biosynthetic process, peptide modification|up regulation of ferricrocin biosynthetic process|positive regulation of ferricrocin anabolism|activation of ferricrocin anabolism|up-regulation of ferricrocin biosynthetic process, peptide formation|upregulation of ferricrocin formation|activation of ferricrocin formation|up regulation of ferricrocin anabolism|upregulation of ferricrocin synthesis|activation of ferricrocin biosynthetic process, peptide formation|activation of ferricrocin biosynthetic process|up-regulation of ferricrocin biosynthesis|up regulation of ferricrocin synthesis|positive regulation of ferricrocin synthesis|up-regulation of ferricrocin biosynthetic process, peptide modification|up regulation of ferricrocin biosynthesis|positive regulation of ferricrocin biosynthetic process, peptide modification|activation of ferricrocin synthesis|up regulation of ferricrocin biosynthetic process, peptide formation|up-regulation of ferricrocin biosynthetic process|upregulation of ferricrocin biosynthesis|up-regulation of ferricrocin formation|upregulation of ferricrocin biosynthetic process|up-regulation of ferricrocin synthesis							di	2012-05-22T04:28:23Z					biological_process											owl:Class	
GO:1900678	biolink:NamedThing	regulation of ferricrocin biosynthetic process	Any process that modulates the frequency, rate or extent of ferricrocin biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of ferricrocin formation|regulation of ferricrocin biosynthetic process, peptide modification|regulation of ferricrocin biosynthetic process, peptide formation|regulation of ferricrocin anabolism|regulation of ferricrocin biosynthesis|regulation of ferricrocin synthesis							di	2012-05-22T04:27:53Z					biological_process											owl:Class	
GO:1902684	biolink:NamedThing	negative regulation of receptor localization to synapse	Any process that stops, prevents or reduces the frequency, rate or extent of receptor localization to synapse.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of receptor localisation to synapse|down-regulation of receptor localisation to synapse|down-regulation of receptor localization to synapse|downregulation of receptor localization to synapse|inhibition of receptor localisation to synapse|downregulation of receptor localisation to synapse|inhibition of receptor localization to synapse|down regulation of receptor localisation to synapse|down regulation of receptor localization to synapse							kmv	2014-02-07T17:38:41Z					biological_process											owl:Class	
GO:0062062	biolink:NamedThing	oligosaccharyltransferase complex binding	Binding to an oligosaccharyltransferase complex.	tmpzr1t_l9r_go_relaxed.owl								dph	2018-08-31T13:56:32Z					molecular_function											owl:Class	
GO:1905441	biolink:NamedThing	response to chondroitin 4'-sulfate	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chondroitin 4'-sulfate stimulus.	tmpzr1t_l9r_go_relaxed.owl								cvs	2016-09-14T18:56:27Z					biological_process											owl:Class	
GO:0072429	biolink:NamedThing	response to intra-S DNA damage checkpoint signaling	A process that occurs in response to signals generated as a result of intra-S DNA damage checkpoint signaling.	tmpzr1t_l9r_go_relaxed.owl	response to signal involved in intra-S DNA damage checkpoint|intra-S DNA damage checkpoint effector process							mah	2010-12-08T04:31:56Z					biological_process											owl:Class	
GO:0072423	biolink:NamedThing	response to DNA damage checkpoint signaling	A process that occurs in response to signals generated as a result of DNA damage checkpoint signaling.	tmpzr1t_l9r_go_relaxed.owl	response to signal involved in DNA damage checkpoint|DNA damage checkpoint effector process							mah	2010-12-08T04:20:25Z					biological_process											owl:Class	
GO:2000969	biolink:NamedThing	positive regulation of AMPA receptor activity	Any process that activates or increases the frequency, rate or extent of AMPA selective glutamate receptor activity.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity							pr	2011-08-03T10:27:08Z					biological_process											owl:Class	
GO:2001259	biolink:NamedThing	positive regulation of cation channel activity	Any process that activates or increases the frequency, rate or extent of cation channel activity.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of cation diffusion facilitator activity|positive regulation of nonselective cation channel activity							vk	2011-12-07T07:14:57Z					biological_process											owl:Class	
GO:0051090	biolink:NamedThing	regulation of DNA-binding transcription factor activity	Any process that modulates the frequency, rate or extent of the activity of a transcription factor, any factor involved in the initiation or regulation of transcription.	tmpzr1t_l9r_go_relaxed.owl	regulation of sequence-specific DNA binding transcription factor activity|regulation of transcription factor activity|regulation of thyroid hormone receptor activity|regulation of androgen receptor activity|regulation of DNA binding transcription factor activity											GO:2000823|GO:1904167		biological_process											owl:Class	
GO:0035566	biolink:NamedThing	regulation of metanephros size	Any process that modulates the size of a metanephric kidney.	tmpzr1t_l9r_go_relaxed.owl	regulation of metanephric kidney size							bf	2010-07-23T11:34:06Z					biological_process											owl:Class	
GO:0002243	biolink:NamedThing	detection of parasitic plant	The series of events in which a stimulus from a parasitic plant is received and converted into a molecular signal.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0009602	biolink:NamedThing	detection of symbiont	The series of events in which a stimulus from a symbiont (an organism living in close physical association with an organism of a different species) is received and converted into a molecular signal. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	recognition of symbiont|perception of symbiont	https://github.com/geneontology/go-ontology/issues/17977										GO:0051855		biological_process											owl:Class	
GO:0022002	biolink:NamedThing	negative regulation of anterior neural cell fate commitment of the neural plate by Wnt signaling pathway	The series of molecular signals that stops, prevents or reduces the frequency or rate at which a cell adopts an anterior neural cell fate, initiated by binding of Wnt protein to a receptor on the surface of the target cell.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of anterior neural cell fate commitment of the neural plate by Wnt-activated signaling pathway|Wnt receptor signaling involved in down regulation of anterior neural cell fate of the neural plate|Wnt receptor signaling involved in inhibition of anterior neural cell fate of the neural plate|Wnt receptor signaling involved in down-regulation of anterior neural cell fate of the neural plate|Wnt receptor signaling involved in negative regulation of anterior neural cell fate of the neural plate|Wnt receptor signalling involved in negative regulation of anterior neural cell fate of the neural plate|negative regulation of anterior neural cell fate commitment of the neural plate by Wnt receptor signaling pathway|Wnt receptor signaling involved in downregulation of anterior neural cell fate of the neural plate													biological_process											owl:Class	
GO:1900981	biolink:NamedThing	negative regulation of phenazine biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of phenazine biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	inhibition of dibenzopyrazine biosynthesis|down-regulation of dibenzopyrazine biosynthetic process|down regulation of azophenylene biosynthetic process|negative regulation of dibenzo-p-diazine biosynthesis|down-regulation of azophenylene biosynthetic process|downregulation of acridizine biosynthesis|downregulation of dibenzopyrazine biosynthesis|downregulation of phenazine biosynthetic process|down regulation of azophenylene biosynthesis|downregulation of dibenzo-p-diazine biosynthetic process|inhibition of phenazine biosynthetic process|negative regulation of dibenzopyrazine biosynthetic process|downregulation of acridizine biosynthetic process|inhibition of dibenzopyrazine biosynthetic process|downregulation of azophenylene biosynthesis|inhibition of dibenzo-p-diazine biosynthesis|down regulation of acridizine biosynthetic process|down regulation of phenazine biosynthetic process|down-regulation of dibenzo-p-diazine biosynthetic process|down regulation of dibenzopyrazine biosynthetic process|down regulation of acridizine biosynthesis|down regulation of dibenzo-p-diazine biosynthesis|negative regulation of azophenylene biosynthetic process|downregulation of azophenylene biosynthetic process|down-regulation of phenazine biosynthetic process|down-regulation of dibenzo-p-diazine biosynthesis|negative regulation of acridizine biosynthetic process|inhibition of acridizine biosynthesis|downregulation of dibenzo-p-diazine biosynthesis|downregulation of dibenzopyrazine biosynthetic process|down-regulation of acridizine biosynthesis|down-regulation of acridizine biosynthetic process|down regulation of dibenzo-p-diazine biosynthetic process|inhibition of azophenylene biosynthetic process|down-regulation of dibenzopyrazine biosynthesis|negative regulation of dibenzo-p-diazine biosynthetic process|negative regulation of dibenzopyrazine biosynthesis|negative regulation of acridizine biosynthesis|negative regulation of azophenylene biosynthesis|inhibition of dibenzo-p-diazine biosynthetic process|down regulation of dibenzopyrazine biosynthesis|inhibition of acridizine biosynthetic process|inhibition of azophenylene biosynthesis|down-regulation of azophenylene biosynthesis							tt	2012-06-14T04:05:03Z					biological_process											owl:Class	
GO:1901904	biolink:NamedThing	tyrocidine biosynthetic process	The chemical reactions and pathways resulting in the formation of tyrocidine.	tmpzr1t_l9r_go_relaxed.owl	tyrocidine biosynthesis|tyrocidine synthesis|tyrocidine formation|tyrocidine anabolism							yaf	2013-02-12T23:40:43Z					biological_process											owl:Class	
GO:1901902	biolink:NamedThing	tyrocidine metabolic process	The chemical reactions and pathways involving tyrocidine.	tmpzr1t_l9r_go_relaxed.owl	tyrocidine metabolism							yaf	2013-02-12T23:40:29Z					biological_process											owl:Class	
GO:2001165	biolink:NamedThing	positive regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues	Any process that activates or increases the frequency, rate or extent of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues.	tmpzr1t_l9r_go_relaxed.owl								se	2011-10-25T10:31:07Z					biological_process											owl:Class	
GO:2001163	biolink:NamedThing	regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues	Any process that modulates the frequency, rate or extent of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues.	tmpzr1t_l9r_go_relaxed.owl								se	2011-10-25T10:30:59Z					biological_process											owl:Class	
GO:0008156	biolink:NamedThing	negative regulation of DNA replication	Any process that stops, prevents, or reduces the frequency, rate or extent of DNA replication.	tmpzr1t_l9r_go_relaxed.owl	downregulation of DNA replication|down regulation of DNA replication|down-regulation of DNA replication|inhibition of DNA replication|DNA replication inhibitor													biological_process											owl:Class	
GO:0014730	biolink:NamedThing	skeletal muscle regeneration at neuromuscular junction	The regrowth of muscle tissue to repair injured or damaged muscle fibers in the postnatal stage at the neuromuscular junction. Regeneration of neuromuscular junctions occurs in an orderly way and relies on communication between nerve and muscle. Skeletal myofibers regenerate after injury and form neuro-muscular junctions with motor axons similar to normal ones. Regenerating myofibers develop within the basal lamina sheaths (satellite cells) of original myofibers.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0043403	biolink:NamedThing	skeletal muscle tissue regeneration	The regrowth of skeletal muscle tissue to repair injured or damaged muscle fibers in the postnatal stage.	tmpzr1t_l9r_go_relaxed.owl	myofiber turnover													biological_process											owl:Class	
GO:0046633	biolink:NamedThing	alpha-beta T cell proliferation	The expansion of an alpha-beta T cell population by cell division.	tmpzr1t_l9r_go_relaxed.owl	alpha-beta T lymphocyte proliferation|alpha-beta T-lymphocyte proliferation|alpha-beta T-cell proliferation													biological_process											owl:Class	
GO:1902341	biolink:NamedThing	xylitol transport	The directed movement of a xylitol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Xylitol is a polyalcohol (pentane-1,2,3,4,5-pentol), produced by hydrogenation of xylose.	tmpzr1t_l9r_go_relaxed.owl								se	2013-07-30T16:04:38Z					biological_process											owl:Class	
GO:2001246	biolink:NamedThing	negative regulation of phosphatidylcholine biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of phosphatidylcholine biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of phosphatidylcholine anabolism|negative regulation of phosphatidylcholine synthesis|negative regulation of phosphatidylcholine formation|negative regulation of phosphatidylcholine biosynthesis							tb	2011-11-28T09:47:47Z					biological_process											owl:Class	
GO:2001245	biolink:NamedThing	regulation of phosphatidylcholine biosynthetic process	Any process that modulates the frequency, rate or extent of phosphatidylcholine biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of phosphatidylcholine formation|regulation of phosphatidylcholine synthesis|regulation of phosphatidylcholine biosynthesis|regulation of phosphatidylcholine anabolism							tb	2011-11-28T09:47:32Z					biological_process											owl:Class	
GO:0046190	biolink:NamedThing	aerobic phenol-containing compound biosynthetic process	The chemical reactions and pathways resulting in the formation of a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring, in the presence of oxygen.	tmpzr1t_l9r_go_relaxed.owl	aerobic phenol-containing compound anabolism|aerobic phenol-containing compound biosynthesis|aerobic phenol-containing compound synthesis|aerobic phenol-containing compound formation													biological_process											owl:Class	
GO:1904628	biolink:NamedThing	cellular response to phorbol 13-acetate 12-myristate	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a phorbol 13-acetate 12-myristate stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to TPA|cellular response to response to PMA|cellular response to phorbol 12-tetradecanoate 13-acetate|cellular response to tetradecanoylphorbol acetate							sl	2015-08-28T13:44:10Z					biological_process											owl:Class	
GO:1904627	biolink:NamedThing	response to phorbol 13-acetate 12-myristate	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a phorbol 13-acetate 12-myristate stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to tetradecanoylphorbol acetate|response to TPA|response to phorbol 12-tetradecanoate 13-acetate|response to PMA							sl	2015-08-28T13:44:03Z					biological_process											owl:Class	
GO:0045778	biolink:NamedThing	positive regulation of ossification	Any process that activates or increases the frequency, rate or extent of ossification, the formation of bone or of a bony substance or the conversion of fibrous tissue or of cartilage into bone or a bony substance.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of ossification|activation of ossification|upregulation of ossification|positive regulation of bone biosynthesis|up regulation of ossification|stimulation of ossification|positive regulation of bone formation													biological_process											owl:Class	
GO:0030278	biolink:NamedThing	regulation of ossification	Any process that modulates the frequency, rate or extent of ossification, the formation of bone or of a bony substance or the conversion of fibrous tissue or of cartilage into bone or a bony substance.	tmpzr1t_l9r_go_relaxed.owl	regulation of bone biosynthesis|regulation of bone formation													biological_process											owl:Class	
GO:0060769	biolink:NamedThing	positive regulation of epithelial cell proliferation involved in prostate gland development	Any process that increases the rate, frequency or extent of epithelial cell proliferation that contributes to the progression of the prostate gland over time.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-07-08T07:38:02Z					biological_process											owl:Class	
GO:0050679	biolink:NamedThing	positive regulation of epithelial cell proliferation	Any process that activates or increases the rate or extent of epithelial cell proliferation.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of epithelial cell proliferation|upregulation of epithelial cell proliferation|stimulation of epithelial cell proliferation|activation of epithelial cell proliferation|up regulation of epithelial cell proliferation													biological_process											owl:Class	
GO:1903668	biolink:NamedThing	negative regulation of chemorepellent activity	Any process that stops, prevents or reduces the frequency, rate or extent of chemorepellent activity.	tmpzr1t_l9r_go_relaxed.owl	downregulation of chemorepellent activity|down-regulation of chemorepellent activity|down regulation of chemorepellent activity|down regulation of chemorepellant activity|negative regulation of chemorepellant activity|inhibition of chemorepellent activity|inhibition of chemorepellant activity|downregulation of chemorepellant activity|down-regulation of chemorepellant activity							pf	2014-11-26T23:58:42Z					biological_process											owl:Class	
GO:1900121	biolink:NamedThing	negative regulation of receptor binding	Any process that stops, prevents or reduces the frequency, rate or extent of a protein or other molecule binding to a receptor.	tmpzr1t_l9r_go_relaxed.owl	inhibition of receptor ligand|down regulation of receptor binding|inhibition of receptor binding|downregulation of receptor binding|down regulation of receptor-associated protein activity|down-regulation of receptor binding							bf	2012-02-22T11:40:57Z					biological_process											owl:Class	
GO:0008282	biolink:NamedThing	inward rectifying potassium channel	A protein complex that comprises four pore-forming (Kir6.x) and four regulatory sulphonylurea receptor (SURx) subunits and forms a transmembrane channel through which ions may pass. The opening and closing of the channel is regulated by ATP: binding of ATP to the Kir6.x subunit inhibits channel activity, whereas binding of Mg2+-complexed ATP or ADP to the SURx subunit stimulates channel activity.	tmpzr1t_l9r_go_relaxed.owl	Kir6.x complex|KCNJ8-SUR complex|ATP-sensitive potassium channel complex|Kir6.2-SURx complex|KCNJ8-SURx complex|Kir6-SUR complex|inward rectifying K+ channel|KCNJ11-SURx complex|Kir6.2-SUR complex|Kir6.1-SUR complex|Kir6.1-SURx complex|KCNJ11-SUR complex|Kir6.x-SURx complex													cellular_component											owl:Class	
GO:0034705	biolink:NamedThing	potassium channel complex	An ion channel complex through which potassium ions pass.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0046662	biolink:NamedThing	regulation of oviposition	Any process that modulates the frequency, rate or extent of the deposition of eggs, either fertilized or not, upon a surface or into a medium.	tmpzr1t_l9r_go_relaxed.owl	regulation of post-mating oviposition											GO:0048042		biological_process											owl:Class	
GO:1903286	biolink:NamedThing	regulation of potassium ion import	Any process that modulates the frequency, rate or extent of potassium ion import.	tmpzr1t_l9r_go_relaxed.owl	regulation of potassium ion uptake|regulation of potassium import							rl	2014-08-11T14:26:16Z					biological_process											owl:Class	
GO:0002870	biolink:NamedThing	T cell anergy	Any process contributing to anergy in T cells, a state of functional inactivation which is part of T cell tolerance induction.	tmpzr1t_l9r_go_relaxed.owl	T lymphocyte anergy|T-cell anergy|T-lymphocyte anergy													biological_process											owl:Class	
GO:0060124	biolink:NamedThing	positive regulation of growth hormone secretion	Any process that increases the frequency, rate or extent of the regulated release of growth hormone from a cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1990392	biolink:NamedThing	EFF-1 complex	A trimeric cell-cell fusion complex that serves as a scaffold for zippering up the extracellular domains, bringing the transmembrane segments into close proximity such that they can continue zippering within the two membranes into one. Two prefusion monomers cluster at the surface of adjacent cells. Parallel EFF-1 interactions occur across cells and a third monomer, which can come from either cell, adds on to make an intermediate, extended trimer.	tmpzr1t_l9r_go_relaxed.owl						An example of this is eff-1 in C. elegans (G5ECA1) in PMID:24725407 (inferred from direct assay).		bhm	2014-06-04T14:45:02Z					cellular_component											owl:Class	
GO:0006106	biolink:NamedThing	fumarate metabolic process	The chemical reactions and pathways involving fumarate, the anion of trans-1,2-ethenedicarboxylic acid, the diastereoisomer of maleate. It is a key intermediate in metabolism and is formed in the TCA cycle from succinate and converted into malate.	tmpzr1t_l9r_go_relaxed.owl	fumarate metabolism													biological_process											owl:Class	
GO:1905043	biolink:NamedThing	positive regulation of epithelium regeneration	Any process that activates or increases the frequency, rate or extent of epithelium regeneration.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of regeneration of epithelium|upregulation of epithelium regeneration|positive regulation of regeneration of epithelium|upregulation of regeneration of epithelium|up-regulation of epithelium regeneration|up regulation of epithelium regeneration|activation of regeneration of epithelium|up regulation of regeneration of epithelium|activation of epithelium regeneration							rph	2016-03-11T10:59:12Z					biological_process											owl:Class	
GO:0075241	biolink:NamedThing	positive regulation of zoospore formation	Any process that activates, maintains or increases the frequency, rate or extent of zoospore formation, a process in which a diploid cell undergoes meiosis, and the meiotic products acquire specialized features of asexual motile mononucleate flagellated spores called zoospores.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0075240	biolink:NamedThing	regulation of zoospore formation	Any process that modulates the frequency, rate or extent of zoospore formation, a process in which a diploid cell undergoes meiosis, and the meiotic products acquire specialized features of asexual motile mononucleate flagellated spores called zoospores.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0043705	biolink:NamedThing	cyanophycin metabolic process	The chemical reactions and pathways involving cyanophycin, a non-protein, non-ribosomally produced amino acid polymer composed of an aspartic acid backbone and arginine side groups.	tmpzr1t_l9r_go_relaxed.owl	multi-L-arginyl-poly(L-aspartic acid) metabolism|cyanophycin metabolism													biological_process											owl:Class	
GO:0008670	biolink:NamedThing	2,4-dienoyl-CoA reductase (NADPH) activity	Catalysis of the reaction: trans-2,3-didehydroacyl-CoA + NADP+ = trans,trans-2,3,4,5-tetradehydroacyl-CoA + NADPH + H+.	tmpzr1t_l9r_go_relaxed.owl	4-enoyl coenzyme A (reduced nicotinamide adenine dinucleotide phosphate) reductase activity|trans-2,3-didehydroacyl-CoA:NADP+ 4-oxidoreductase activity|4-enoyl-CoA reductase activity|4-enoyl-CoA reductase (NADPH) activity|4-enoyl-CoA reductase (NADPH2)				RHEA:12136|MetaCyc:DIENOYLCOAREDUCT-RXN|EC:1.3.1.34									molecular_function											owl:Class	
GO:1900707	biolink:NamedThing	regulation of tensidol A biosynthetic process	Any process that modulates the frequency, rate or extent of tensidol A biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of tensidol A formation|regulation of tensidol A anabolism|regulation of tensidol A synthesis|regulation of tensidol A biosynthesis							di	2012-05-22T05:01:44Z					biological_process											owl:Class	
GO:1901393	biolink:NamedThing	negative regulation of transforming growth factor beta1 activation	Any process that stops, prevents or reduces the frequency, rate or extent of transforming growth factor beta1 activation.	tmpzr1t_l9r_go_relaxed.owl	downregulation of TGFbeta 1 activation|down-regulation of transforming growth factor beta1 activation|down-regulation of transforming growth factor-beta1 activation|downregulation of L-TGF-beta 1 activation|negative regulation of transforming growth factor-beta1 activation|downregulation of TGF-beta 1 activation|downregulation of TGFB1 activation|inhibition of TGFB1 activation|down regulation of TGFB1 activation|down regulation of latent-TGF-beta1 activation|down-regulation of latent-TGF-beta1 activation|negative regulation of TGFB1 activation|down regulation of L-TGF-beta 1 activation|negative regulation of L-TGF-beta 1 activation|downregulation of transforming growth factor-beta1 activation|downregulation of transforming growth factor beta1 activation|down regulation of transforming growth factor beta1 activation|inhibition of TGFbeta 1 activation|down-regulation of L-TGF-beta 1 activation|negative regulation of TGFbeta 1 activation|down-regulation of TGF-beta 1 activation|down-regulation of TGFbeta 1 activation|inhibition of TGF-beta 1 activation|inhibition of transforming growth factor beta1 activation|down regulation of TGFbeta 1 activation|down-regulation of TGFB1 activation|inhibition of transforming growth factor-beta1 activation|negative regulation of TGF-beta 1 activation|inhibition of L-TGF-beta 1 activation|downregulation of latent-TGF-beta1 activation|negative regulation of latent-TGF-beta1 activation|inhibition of latent-TGF-beta1 activation|down regulation of TGF-beta 1 activation|down regulation of transforming growth factor-beta1 activation							bf	2012-10-01T10:41:17Z					biological_process											owl:Class	
GO:1903880	biolink:NamedThing	17alpha-hydroxyprogesterone binding	Binding to 17alpha-hydroxyprogesterone.	tmpzr1t_l9r_go_relaxed.owl								mr	2015-02-06T16:03:22Z					molecular_function											owl:Class	
GO:2001026	biolink:NamedThing	regulation of endothelial cell chemotaxis	Any process that modulates the frequency, rate or extent of endothelial cell chemotaxis.	tmpzr1t_l9r_go_relaxed.owl								rl	2011-08-22T01:07:26Z					biological_process											owl:Class	
GO:0015812	biolink:NamedThing	gamma-aminobutyric acid transport	The directed movement of gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	4-aminobutyrate transport|GABA transport|4-aminobutanoate transport					See also the biological process term 'neurotransmitter transport ; GO:0006836'.								biological_process											owl:Class	
GO:0071953	biolink:NamedThing	elastic fiber	An supramolecular fiber that consists of an insoluble core of polymerized tropoelastin monomers and a surrounding mantle of microfibrils. Elastic fibers provide elasticity and recoiling to tissues and organs, and maintain structural integrity against mechanical strain.	tmpzr1t_l9r_go_relaxed.owl	elastic fibre|elastin fiber							mah	2010-10-11T11:44:57Z					cellular_component											owl:Class	
GO:0099512	biolink:NamedThing	supramolecular fiber	A polymer consisting of an indefinite number of protein or protein complex subunits that have polymerised to form a fiber-shaped structure.	tmpzr1t_l9r_go_relaxed.owl	fibril											GO:0043205		cellular_component											owl:Class	
GO:1904816	biolink:NamedThing	positive regulation of protein localization to chromosome, telomeric region	Any process that activates or increases the frequency, rate or extent of protein localization to chromosome, telomeric region.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of protein localisation to chromosome, telomeric region|upregulation of protein localisation to chromosome, telomeric region|up-regulation of protein localization to chromosome, telomeric region|up regulation of protein localisation to chromosome, telomeric region|activation of protein localisation to chromosome, telomeric region|activation of protein localization to chromosome, telomeric region|up regulation of protein localization to chromosome, telomeric region|upregulation of protein localization to telomere|positive regulation of protein localization to telomere|up-regulation of protein localisation to chromosome, telomeric region|upregulation of protein localization to chromosome, telomeric region|up regulation of protein localization to telomere|activation of protein localization to telomere|up-regulation of protein localization to telomere							nc	2015-11-16T12:18:58Z					biological_process											owl:Class	
GO:0016667	biolink:NamedThing	oxidoreductase activity, acting on a sulfur group of donors	Catalysis of an oxidation-reduction (redox) reaction in which a sulfur-containing group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.	tmpzr1t_l9r_go_relaxed.owl	oxidoreductase activity, acting on sulfur group of donors, other acceptors|oxidoreductase activity, acting on sulphur group of donors				EC:1.8.-.-|Reactome:R-HSA-2213240									molecular_function											owl:Class	
GO:0046444	biolink:NamedThing	FMN metabolic process	The chemical reactions and pathways involving FMN, riboflavin 5'-(dihydrogen phosphate), a coenzyme for a number of oxidative enzymes including NADH dehydrogenase.	tmpzr1t_l9r_go_relaxed.owl	FMN metabolism													biological_process											owl:Class	
GO:0042726	biolink:NamedThing	flavin-containing compound metabolic process	The chemical reactions and pathways involving a flavin, any derivative of the dimethylisoalloxazine (7,8-dimethylbenzo[g]pteridine-2,4(3H,10H)-dione) skeleton, with a substituent on the 10 position.	tmpzr1t_l9r_go_relaxed.owl	riboflavin and derivative metabolism|flavin-containing compound metabolism|vitamin B2 and derivative metabolism|vitamin B2 and derivative metabolic process|riboflavin and derivative metabolic process													biological_process											owl:Class	
GO:0002749	biolink:NamedThing	antigen processing and presentation initiated by toll-like receptor mediated phagocytosis of antigen	Antigen processing and presentation which is initiated by phagocytosis of antigen bound directly or indirectly to a cell surface toll-like receptor (TLR).	tmpzr1t_l9r_go_relaxed.owl	antigen processing and presentation initiated by TLR mediated phagocytosis of antigen													biological_process											owl:Class	
GO:0002747	biolink:NamedThing	antigen processing and presentation following phagocytosis	Antigen processing and presentation which is initiated by uptake of antigen via phagocytosis.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0002932	biolink:NamedThing	tendon sheath development	The process whose specific outcome is the progression of a tendon sheath over time, from its formation to the mature structure. A tendon sheath is a layer of membrane around a tendon. It permits the tendon to move.	tmpzr1t_l9r_go_relaxed.owl								hjd	2012-04-23T02:11:22Z					biological_process											owl:Class	
GO:0005880	biolink:NamedThing	nuclear microtubule	Any microtubule in the nucleus of a cell.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0005874	biolink:NamedThing	microtubule	Any of the long, generally straight, hollow tubes of internal diameter 12-15 nm and external diameter 24 nm found in a wide variety of eukaryotic cells; each consists (usually) of 13 protofilaments of polymeric tubulin, staggered in such a manner that the tubulin monomers are arranged in a helical pattern on the microtubular surface, and with the alpha/beta axes of the tubulin subunits parallel to the long axis of the tubule; exist in equilibrium with pool of tubulin monomers and can be rapidly assembled or disassembled in response to physiological stimuli; concerned with force generation, e.g. in the spindle.	tmpzr1t_l9r_go_relaxed.owl	microtubuli|neurotubule|microtubulus				NIF_Subcellular:sao1846835077|Wikipedia:Microtubule									cellular_component											owl:Class	
GO:0075255	biolink:NamedThing	teliospore formation	The set of processes leading to the formation of a thick-walled resting or over-wintering spore produced by the rust fungi (Uredinales) and smut fungi (Ustilaginales) in which karyogamy occurs.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0006887	biolink:NamedThing	exocytosis	A process of secretion by a cell that results in the release of intracellular molecules (e.g. hormones, matrix proteins) contained within a membrane-bounded vesicle. Exocytosis can occur either by full fusion, when the vesicle collapses into the plasma membrane, or by a kiss-and-run mechanism that involves the formation of a transient contact, a pore, between a granule (for exemple of chromaffin cells) and the plasma membrane. The latter process most of the time leads to only partial secretion of the granule content. Exocytosis begins with steps that prepare vesicles for fusion with the membrane (tethering and docking) and ends when molecules are secreted from the cell.	tmpzr1t_l9r_go_relaxed.owl	vesicle exocytosis|nonselective vesicle exocytosis				Wikipedia:Exocytosis							GO:0016194|GO:0016195		biological_process											owl:Class	
GO:0032940	biolink:NamedThing	secretion by cell	The controlled release of a substance by a cell.	tmpzr1t_l9r_go_relaxed.owl	cellular secretion				Wikipedia:Secretion									biological_process											owl:Class	
GO:0039594	biolink:NamedThing	endoribonuclease activity involved in viral induction of host mRNA catabolic process	Any endoribonuclease activity that contributes to the viral-induced catabolism of host mRNA.	tmpzr1t_l9r_go_relaxed.owl						GO:0039594 can be used to annotate a host or viral endoribonuclease activity that cleaves host mRNA in response to a viral infection.		bf	2012-07-05T11:21:26Z					molecular_function											owl:Class	
GO:1990109	biolink:NamedThing	rejection of pollen from other species	The process involved in the rejection of pollen of one species by cells in the stigma of another species.	tmpzr1t_l9r_go_relaxed.owl	unilateral interspecific incompatibility							tb	2013-05-29T21:12:09Z					biological_process											owl:Class	
GO:2000541	biolink:NamedThing	positive regulation of protein geranylgeranylation	Any process that activates or increases the frequency, rate or extent of protein geranylgeranylation.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of protein amino acid geranylgeranylation|positive regulation of C-terminal protein geranylgeranylation							tb	2011-03-29T06:23:15Z					biological_process											owl:Class	
GO:0000755	biolink:NamedThing	cytogamy	During conjugation with cellular fusion, the process resulting in creating a single cell from complementary mating types. The localized remodeling and dissolution of external protective structures allow the fusion of the plasma membranes and cytoplasmic mixing. An example of this process is found in Saccharomyces cerevisiae.	tmpzr1t_l9r_go_relaxed.owl	zygote formation											GO:0030462|GO:0000218		biological_process											owl:Class	
GO:0022413	biolink:NamedThing	reproductive process in single-celled organism	A process, occurring at the cellular level, that is involved in the reproductive function of a single-celled organism.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0036035	biolink:NamedThing	osteoclast development	The process whose specific outcome is the progression of a osteoclast from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate. An osteoclast is a specialized phagocytic cell associated with the absorption and removal of the mineralized matrix of bone tissue.	tmpzr1t_l9r_go_relaxed.owl	osteoclast cell development							bf	2011-11-02T05:20:35Z					biological_process											owl:Class	
GO:0098751	biolink:NamedThing	bone cell development	The process whose specific outcome is the progression of a bone cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.	tmpzr1t_l9r_go_relaxed.owl						Not to be used for manual annotation.  Please choose a more specific cell development term or if not possible, bone or bone tissue development.								biological_process											owl:Class	
GO:0042827	biolink:NamedThing	platelet dense granule	Electron-dense granule occurring in blood platelets that stores and secretes adenosine nucleotides and serotonin. They contain a highly condensed core consisting of serotonin, histamine, calcium, magnesium, ATP, ADP, pyrophosphate and membrane lysosomal proteins.	tmpzr1t_l9r_go_relaxed.owl	bull's eye body|platelet dense body													cellular_component											owl:Class	
GO:0072196	biolink:NamedThing	proximal/distal pattern formation involved in pronephric nephron development	The regionalization process in which specific areas of cell differentiation are determined along a proximal/distal axis of the pronephros.	tmpzr1t_l9r_go_relaxed.owl	pronephros proximal/distal pattern formation							mah	2010-03-01T02:11:07Z					biological_process											owl:Class	
GO:0072047	biolink:NamedThing	proximal/distal pattern formation involved in nephron development	The regionalization process in which specific areas of cell differentiation are determined along a proximal/distal axis of a nephron. The proximal/distal axis is defined by a line that runs from the center of the kidney (proximal end) outward (distal end).	tmpzr1t_l9r_go_relaxed.owl	proximal/distal nephron patterning|proximal-distal pattern formation involved in nephron development							mah	2010-01-25T03:30:48Z					biological_process											owl:Class	
GO:1900267	biolink:NamedThing	positive regulation of substance P receptor binding	Any process that activates or increases the frequency, rate or extent of substance P receptor binding.	tmpzr1t_l9r_go_relaxed.owl	upregulation of neurokinin-1 receptor binding|up regulation of substance P receptor binding|up-regulation of substance P receptor ligand|activation of neurokinin-1 receptor binding|upregulation of substance P receptor ligand|up-regulation of substance P receptor binding|activation of substance P receptor binding|positive regulation of neurokinin-1 receptor binding|up-regulation of neurokinin-1 receptor binding|activation of substance P receptor ligand|positive regulation of substance P receptor ligand|upregulation of substance P receptor binding|up regulation of substance P receptor ligand|up regulation of neurokinin-1 receptor binding							tb	2012-04-03T11:11:45Z					biological_process											owl:Class	
GO:1900265	biolink:NamedThing	regulation of substance P receptor binding	Any process that modulates the frequency, rate or extent of substance P receptor binding.	tmpzr1t_l9r_go_relaxed.owl	regulation of substance P receptor ligand|regulation of neurokinin-1 receptor binding							tb	2012-04-03T11:11:27Z					biological_process											owl:Class	
GO:0034119	biolink:NamedThing	negative regulation of erythrocyte aggregation	Any process that stops, prevents, or reduces the frequency, rate, or extent of erythrocyte aggregation.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of red blood cell aggregation|negative regulation of RBC aggregation													biological_process											owl:Class	
GO:0034118	biolink:NamedThing	regulation of erythrocyte aggregation	Any process that modulates the frequency, rate, or extent of erythrocyte aggregation.	tmpzr1t_l9r_go_relaxed.owl	regulation of red blood cell aggregation|regulation of RBC aggregation													biological_process											owl:Class	
GO:0099106	biolink:NamedThing	ion channel regulator activity	Modulates the activity of a channel via direct interaction with it. A channel catalyzes energy-independent facilitated diffusion, mediated by passage of a solute through a transmembrane aqueous pore or channel.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0140456	biolink:NamedThing	initial meiotic spindle pole body separation	The release of duplicated meiotic spindle pole bodies (SPBs).	tmpzr1t_l9r_go_relaxed.owl	meiotic spindle pole body duplication|initial spindle pole body separation involved in meiosis I	https://github.com/geneontology/go-ontology/issues/17971						pg	2020-04-22T19:07:22Z					biological_process											owl:Class	
GO:0042666	biolink:NamedThing	negative regulation of ectodermal cell fate specification	Any process that restricts, stops or prevents a cell from specifying into an ectoderm cell.	tmpzr1t_l9r_go_relaxed.owl	suppression of ectoderm cell fate|suppression of ectodermal cell fate|negative regulation of ectoderm cell fate specification|inhibition of ectodermal cell fate specification|down-regulation of ectodermal cell fate specification|down regulation of ectodermal cell fate specification|downregulation of ectodermal cell fate specification													biological_process											owl:Class	
GO:0046833	biolink:NamedThing	positive regulation of RNA export from nucleus	Any process that activates or increases the frequency, rate or extent of directed movement of RNA from the nucleus into the cytoplasm.	tmpzr1t_l9r_go_relaxed.owl	activation of RNA export from nucleus|positive regulation of RNA transport from nucleus to cytoplasm|up regulation of RNA export from nucleus|up-regulation of RNA export from nucleus|positive regulation of RNA-nucleus export|upregulation of RNA export from nucleus|stimulation of RNA export from nucleus|positive regulation of RNA export out of nucleus|positive regulation of RNA export from cell nucleus													biological_process											owl:Class	
GO:0046831	biolink:NamedThing	regulation of RNA export from nucleus	Any process that modulates the frequency, rate or extent of the directed movement of RNA from the nucleus to the cytoplasm.	tmpzr1t_l9r_go_relaxed.owl	regulation of RNA transport from nucleus to cytoplasm|regulation of RNA export from cell nucleus|regulation of RNA-nucleus export|regulation of RNA export out of nucleus													biological_process											owl:Class	
GO:1902571	biolink:NamedThing	regulation of serine-type peptidase activity	Any process that modulates the frequency, rate or extent of serine-type peptidase activity.	tmpzr1t_l9r_go_relaxed.owl	regulation of serine protease activity							krc	2013-12-10T18:16:58Z					biological_process											owl:Class	
GO:1905816	biolink:NamedThing	negative regulation of dorsal/ventral axon guidance	Any process that stops, prevents or reduces the frequency, rate or extent of dorsal/ventral axon guidance.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of dorsal/ventral axon pathfinding|down regulation of dorsal-ventral axon guidance|negative regulation of dorsal/ventral axon pathfinding|down-regulation of dorsal-ventral axon guidance|inhibition of dorsal-ventral axon guidance|downregulation of dorsoventral axon guidance|inhibition of dorsal/ventral axon pathfinding|down regulation of dorsal/ventral axon pathfinding|inhibition of dorsal/ventral axon guidance|down-regulation of dorsal/ventral axon guidance|negative regulation of dorsal-ventral axon guidance|inhibition of dorsoventral axon guidance|down regulation of dorsoventral axon guidance|downregulation of dorsal/ventral axon guidance|negative regulation of dorsoventral axon guidance|downregulation of dorsal-ventral axon guidance|down regulation of dorsal/ventral axon guidance|down-regulation of dorsoventral axon guidance|downregulation of dorsal/ventral axon pathfinding							hbye	2017-01-12T13:38:53Z					biological_process											owl:Class	
GO:0031944	biolink:NamedThing	negative regulation of glucocorticoid metabolic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving glucocorticoids.	tmpzr1t_l9r_go_relaxed.owl	inhibition of glucocorticoid metabolic process|negative regulation of glucocorticoid metabolism|downregulation of glucocorticoid metabolic process|down-regulation of glucocorticoid metabolic process|down regulation of glucocorticoid metabolic process													biological_process											owl:Class	
GO:0045939	biolink:NamedThing	negative regulation of steroid metabolic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving steroids.	tmpzr1t_l9r_go_relaxed.owl	down regulation of steroid metabolic process|downregulation of steroid metabolic process|down-regulation of steroid metabolic process|inhibition of steroid metabolic process|negative regulation of steroid metabolism													biological_process											owl:Class	
GO:0034409	biolink:NamedThing	ascospore wall (1->3)-beta-D-glucan metabolic process	The chemical reactions and pathways involving (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds, found in the walls of ascospores.	tmpzr1t_l9r_go_relaxed.owl	ascospore wall 1,3-beta-D-glucan metabolic process|ascospore wall 1,3-beta-glucan metabolic process|ascospore wall 1,3-beta-glucan metabolism|ascospore wall beta-1,3 glucan metabolism|ascospore wall beta-1,3 glucan metabolic process													biological_process											owl:Class	
GO:0071969	biolink:NamedThing	fungal-type cell wall (1->3)-beta-D-glucan metabolic process	The chemical reactions and pathways involving (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds, found in the walls of fungi.	tmpzr1t_l9r_go_relaxed.owl	fungal-type cell wall 1,3-beta-glucan metabolism|fungal-type cell wall 1,3-beta-D-glucan metabolic process|fungal-type cell wall beta-1,3 glucan metabolism|fungal-type cell wall beta-1,3 glucan metabolic process							mah	2010-10-18T03:25:38Z					biological_process											owl:Class	
GO:0051952	biolink:NamedThing	regulation of amine transport	Any process that modulates the frequency, rate or extent of the directed movement of amines into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0007476	biolink:NamedThing	imaginal disc-derived wing morphogenesis	The process in which the anatomical structures of the imaginal disc-derived wing are generated and organized. The wing is an appendage modified for flying.	tmpzr1t_l9r_go_relaxed.owl	wing morphogenesis													biological_process											owl:Class	
GO:0035114	biolink:NamedThing	imaginal disc-derived appendage morphogenesis	The process in which the anatomical structures of appendages are generated and organized. An appendage is an organ or part that is attached to the trunk of an organism.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0047481	biolink:NamedThing	D-alanine-alanyl-poly(glycerolphosphate) ligase activity	Catalysis of the reaction: alanyl-poly(glycerolphosphate) + D-alanine + ATP = D-alanyl-alanyl-poly(glycerolphosphate) + phosphate + ADP.	tmpzr1t_l9r_go_relaxed.owl	D-alanine:alanyl-poly(glycerolphosphate) ligase (ADP-forming)|D-alanyl-alanyl-poly(glycerolphosphate) synthetase activity|D-alanyl-poly(phosphoglycerol) synthetase activity|D-alanine:membrane-acceptor ligase activity|D-alanine-membrane acceptor-ligase activity|D-alanylalanylpoly(phosphoglycerol) synthetase activity				EC:6.3.2.16|MetaCyc:6.3.2.16-RXN									molecular_function											owl:Class	
GO:0052915	biolink:NamedThing	23S rRNA (guanine(2445)-N(2))-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + guanosine(2445) in 23S rRNA = N(2)-methylguanosine(2445) in 23S rRNA + S-adenosyl-L-homocysteine.	tmpzr1t_l9r_go_relaxed.owl					RHEA:42740|EC:2.1.1.173|KEGG_REACTION:R07234|MetaCyc:RXN-11574									molecular_function											owl:Class	
GO:0098928	biolink:NamedThing	presynaptic signal transduction	Signal transduction in which the initial step occurs in a presynapse.	tmpzr1t_l9r_go_relaxed.owl	presynaptic signaling pathway					Do not directly annotate. This term intended for grouping.  Annotate to either a subclass or to some other subclass of signal transduction  extended with has_start_location/occurs_in presynapse or one of its parts.  Such extensions will result in automatic annotation to this term.								biological_process											owl:Class	
GO:1901309	biolink:NamedThing	negative regulation of sterol regulatory element binding protein cleavage	Any process that stops, prevents or reduces the frequency, rate or extent of sterol regulatory element binding protein cleavage.	tmpzr1t_l9r_go_relaxed.owl	downregulation of sterol regulatory element binding protein cleavage|inhibition of SREBP cleavage|down-regulation of sterol regulatory element binding protein cleavage|downregulation of SREBP cleavage|down regulation of sterol regulatory element binding protein cleavage|down regulation of SREBP cleavage|inhibition of SREBP processing|inhibition of sterol regulatory element binding protein cleavage|down-regulation of SREBP cleavage|negative regulation of SREBP cleavage							bf	2012-08-21T16:43:32Z					biological_process											owl:Class	
GO:2000639	biolink:NamedThing	negative regulation of SREBP signaling pathway	Any process that stops, prevents or reduces the frequency, rate or extent of the SREBP signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of SREBP-mediated signalling pathway|negative regulation of SREBP-mediated signaling pathway							vk	2011-04-20T02:46:02Z					biological_process											owl:Class	
GO:1903744	biolink:NamedThing	positive regulation of anterograde synaptic vesicle transport	Any process that activates or increases the frequency, rate or extent of anterograde synaptic vesicle transport.	tmpzr1t_l9r_go_relaxed.owl	upregulation of anterograde synaptic vesicle transport|up regulation of anterograde synaptic vesicle transport|up-regulation of anterograde synaptic vesicle transport|activation of anterograde synaptic vesicle transport							kmv	2014-12-12T16:28:46Z					biological_process											owl:Class	
GO:0031352	biolink:NamedThing	intrinsic component of plastid inner membrane	The component of the plastid inner membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.	tmpzr1t_l9r_go_relaxed.owl	intrinsic to plastid inner membrane													cellular_component											owl:Class	
GO:0051588	biolink:NamedThing	regulation of neurotransmitter transport	Any process that modulates the frequency, rate or extent of the directed movement of a neurotransmitter into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0019560	biolink:NamedThing	histidine catabolic process to hydantoin-5-propionate	The chemical reactions and pathways resulting in the breakdown of histidine into other compounds, including hydantoin-5-propionate.	tmpzr1t_l9r_go_relaxed.owl	histidine degradation to hydantoin-5-propionate|histidine breakdown to hydantoin-5-propionate				MetaCyc:HISHP-PWY									biological_process											owl:Class	
GO:0018900	biolink:NamedThing	dichloromethane metabolic process	The chemical reactions and pathways involving dichloromethane, a dichlorinated derivative of methane. It is a colorless organic liquid with a sweet, chloroform-like odor, often used as a paint remover.	tmpzr1t_l9r_go_relaxed.owl	dichloromethane metabolism				UM-BBD_pathwayID:dcm									biological_process											owl:Class	
GO:0042197	biolink:NamedThing	halogenated hydrocarbon metabolic process	The chemical reactions and pathways involving halogenated hydrocarbons, compounds derived from hydrocarbons by replacing one or more hydrogen atoms with halogen atoms. Halogens include fluorine, chlorine, bromine and iodine.	tmpzr1t_l9r_go_relaxed.owl	halogenated hydrocarbon metabolism													biological_process											owl:Class	
GO:0047734	biolink:NamedThing	CDP-glycerol diphosphatase activity	Catalysis of the reaction: CDP-glycerol + H(2)O = sn-glycerol 3-phosphate + CMP + 2 H(+).	tmpzr1t_l9r_go_relaxed.owl	CDP-glycerol pyrophosphatase activity|cytidine diphosphoglycerol pyrophosphatase activity|CDP-glycerol phosphoglycerohydrolase activity|CDPglycerol diphosphatase activity|CDPglycerol pyrophosphatase activity|CDPglycerol phosphoglycerohydrolase activity				MetaCyc:CDP-GLYCEROL-PYROPHOSPHATASE-RXN|EC:3.6.1.16|KEGG_REACTION:R00855|RHEA:21692									molecular_function											owl:Class	
GO:0045321	biolink:NamedThing	leukocyte activation	A change in morphology and behavior of a leukocyte resulting from exposure to a specific antigen, mitogen, cytokine, cellular ligand, or soluble factor.	tmpzr1t_l9r_go_relaxed.owl	immune cell activation|leucocyte activation				Wikipedia:Immunologic_activation									biological_process											owl:Class	
GO:0033305	biolink:NamedThing	chlorophyll a biosynthetic process	The chemical reactions and pathways leading to the formation of chlorophyll a.	tmpzr1t_l9r_go_relaxed.owl	chlorophyll a formation|chlorophyll a anabolism|chlorophyll a synthesis|chlorophyll a biosynthesis													biological_process											owl:Class	
GO:0033304	biolink:NamedThing	chlorophyll a metabolic process	The chemical reactions and pathways involving chlorophyll a.	tmpzr1t_l9r_go_relaxed.owl	chlorophyll a metabolism													biological_process											owl:Class	
GO:0055052	biolink:NamedThing	ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing	A complex for the transport of metabolites into the cell, consisting of 5 subunits: two ATP-binding subunits, two membrane spanning subunits, and one substrate-binding subunit. In organisms with two membranes, the substrate-binding protein moves freely in the periplasmic space and joins the other subunits only when bound with substrate. In organisms with only one membrane the substrate-binding protein is tethered to the cytoplasmic membrane and associated with the other subunits. Transport of the substrate across the membrane is driven by the hydrolysis of ATP.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0043190	biolink:NamedThing	ATP-binding cassette (ABC) transporter complex	A complex for the transport of metabolites into and out of the cell, typically comprised of four domains; two membrane-associated domains and two ATP-binding domains at the intracellular face of the membrane, that form a central pore through the plasma membrane. Each of the four core domains may be encoded as a separate polypeptide or the domains can be fused in any one of a number of ways into multidomain polypeptides. In Bacteria and Archaebacteria, ABC transporters also include substrate binding proteins to bind substrate external to the cytoplasm and deliver it to the transporter.	tmpzr1t_l9r_go_relaxed.owl	ABC-type uptake permease complex|ABC-type efflux porter complex|ABC-type efflux permease complex|mating pheromone exporter											GO:0043192|GO:0043191		cellular_component											owl:Class	
GO:0110161	biolink:NamedThing	positive regulation of mitotic spindle formation (spindle phase one)	Any process that activates or increases the frequency, rate or extent of the cell cycle process in which the distance is lengthened between poles of the mitotic spindle during mitotic prophase (spindle phase one).	tmpzr1t_l9r_go_relaxed.owl								kmv	2019-08-12T15:21:08Z					biological_process											owl:Class	
GO:1905832	biolink:NamedThing	positive regulation of spindle assembly	Any process that activates or increases the frequency, rate or extent of spindle assembly.	tmpzr1t_l9r_go_relaxed.owl	up regulation of spindle assembly|up-regulation of spindle biosynthesis|upregulation of bipolar spindle biosynthesis|positive regulation of bipolar spindle formation|activation of spindle biosynthesis|activation of spindle formation|upregulation of spindle formation|positive regulation of spindle formation|up-regulation of bipolar spindle formation|activation of bipolar spindle biosynthesis|activation of bipolar spindle formation|up regulation of bipolar spindle formation|upregulation of spindle biosynthesis|up-regulation of spindle formation|upregulation of spindle assembly|upregulation of bipolar spindle formation|up-regulation of bipolar spindle biosynthesis|positive regulation of bipolar spindle biosynthesis|up regulation of spindle formation|positive regulation of spindle biosynthesis|up regulation of bipolar spindle biosynthesis|up regulation of spindle biosynthesis|activation of spindle assembly|up-regulation of spindle assembly							hbye	2017-01-17T10:26:46Z					biological_process											owl:Class	
GO:0035216	biolink:NamedThing	haltere disc development	Progression of the haltere imaginal disc over time, from its initial formation through to its metamorphosis to form the adult capitellum, pedicel, haltere sclerite, metathoracic spiracle and metanotum.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0003865	biolink:NamedThing	3-oxo-5-alpha-steroid 4-dehydrogenase activity	Catalysis of the reaction: a 3-oxo-5-alpha-steroid + acceptor = a 3-oxo-delta(4)-steroid + reduced acceptor.	tmpzr1t_l9r_go_relaxed.owl	delta4-3-oxosteroid-5alpha-reductase|steroid 5 alpha reductase|4-ene-3-ketosteroid-5alpha-oxidoreductase activity|delta4-5alpha-dehydrogenase activity|3-keto-delta4-steroid-5alpha-reductase activity|delta4-3-oxo steroid reductase activity|3-oxo-5alpha-steroid 4-dehydrogenase activity|delta4-3-keto steroid 5alpha-reductase activity|3-oxo-5alpha-steroid:acceptor delta4-oxidoreductase activity|3-oxo-5alpha-steroid:(acceptor) delta4-oxidoreductase activity|testosterone 5alpha-reductase|steroid delta4-5alpha-reductase activity|5alpha-reductase|steroid 5alpha-reductase|steroid 5-alpha-reductase activity|3-oxo-5alpha-steroid delta4-dehydrogenase activity|3-oxosteroid delta4-dehydrogenase|delta4-3-ketosteroid5alpha-oxidoreductase activity				EC:1.3.99.5|Reactome:R-HSA-9705714|MetaCyc:1.3.99.5-RXN|Reactome:R-HSA-469659|Reactome:R-HSA-9705713									molecular_function											owl:Class	
GO:0033765	biolink:NamedThing	steroid dehydrogenase activity, acting on the CH-CH group of donors	Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor, and in which one substrate is a sterol derivative.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0009106	biolink:NamedThing	lipoate metabolic process	The chemical reactions and pathways involving lipoate, 1,2-dithiolane-3-pentanoate, the anion derived from lipoic acid.	tmpzr1t_l9r_go_relaxed.owl	lipoic acid metabolic process|lipoic acid metabolism|lipoate metabolism											GO:0000273		biological_process											owl:Class	
GO:0039708	biolink:NamedThing	nuclear capsid assembly	The assembly of a virus capsid that occurs in the nucleus. The assembly of large icosahedral shells for herpesviridae and adenoviridae requires structural proteins that act as chaperones for assembly.	tmpzr1t_l9r_go_relaxed.owl					VZ:1516			bf	2013-11-28T15:08:41Z					biological_process											owl:Class	
GO:0019069	biolink:NamedThing	viral capsid assembly	The assembly of a virus capsid from its protein subunits.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0047237	biolink:NamedThing	glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity	Catalysis of the reaction: D-glucuronyl-1,3-beta-D-galactosylproteoglycan + UDP-N-acetylgalactosamine = N-acetyl-D-galactosaminyl-1,4-beta-D-glucuronyl-1,3-beta-D-galactosylproteoglycan + UDP.	tmpzr1t_l9r_go_relaxed.owl	N-acetylgalactosaminyltransferase I activity|UDP-N-acetyl-D-galactosamine:D-glucuronyl-1,3-beta-D-galactosyl-proteoglycan beta-1,4-N-acetylgalactosaminyltransferase activity|glucuronylgalactosylproteoglycan beta-1,4-N-acetylgalactosaminyltransferase activity|uridine diphosphoacetylgalactosamine-chondroitin acetylgalactosaminyltransferase I|uridine diphosphoacetylgalactosamine-chondroitinacetylgalactosaminyltransferase I activity				EC:2.4.1.174|MetaCyc:2.4.1.174-RXN|RHEA:23464									molecular_function											owl:Class	
GO:1904226	biolink:NamedThing	regulation of glycogen synthase activity, transferring glucose-1-phosphate	Any process that modulates the frequency, rate or extent of glycogen synthase activity, transferring glucose-1-phosphate.	tmpzr1t_l9r_go_relaxed.owl								rl	2015-05-15T09:23:08Z					biological_process											owl:Class	
GO:0001505	biolink:NamedThing	regulation of neurotransmitter levels	Any process that modulates levels of neurotransmitter.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0102500	biolink:NamedThing	beta-maltose 4-alpha-glucanotransferase activity	Catalysis of the reaction: beta-D-glucose + a plant soluble heteroglycan = a plant soluble heteroglycan + maltose.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-14354|EC:2.4.1.25									molecular_function											owl:Class	
GO:0102773	biolink:NamedThing	dihydroceramide kinase activity	Catalysis of the reaction: ATP + a dihydroceramide = ADP + H+ + a dihydroceramide 1-phosphate.	tmpzr1t_l9r_go_relaxed.owl					EC:2.7.1.138|MetaCyc:RXN-7799									molecular_function											owl:Class	
GO:0009074	biolink:NamedThing	aromatic amino acid family catabolic process	The chemical reactions and pathways resulting in the breakdown of aromatic amino acid family, amino acids with aromatic ring (phenylalanine, tyrosine, tryptophan).	tmpzr1t_l9r_go_relaxed.owl	aromatic amino acid family catabolism|aromatic amino acid family degradation|aromatic amino acid family breakdown													biological_process											owl:Class	
GO:0043945	biolink:NamedThing	positive regulation of asexual sporulation resulting in formation of a cellular spore	Any process that activates, maintains or increases the frequency, rate or extent of the formation of a cellular spore derived from the products of mitosis.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0050820	biolink:NamedThing	positive regulation of coagulation	Any process that activates or increases the frequency, rate or extent of coagulation.	tmpzr1t_l9r_go_relaxed.owl	up regulation of coagulation|activation of coagulation|stimulation of coagulation|upregulation of coagulation|up-regulation of coagulation|positive regulation of clotting													biological_process											owl:Class	
GO:0015538	biolink:NamedThing	sialic acid:proton symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sialate(out) + H+(out) = sialate(in) + H+(in).	tmpzr1t_l9r_go_relaxed.owl	sialic acid:hydrogen symporter activity|sialic acid permease activity				Reactome:R-HSA-428585|RHEA:28987|Reactome:R-HSA-5624239									molecular_function											owl:Class	
GO:0006257	biolink:NamedThing	dUDP catabolic process	The chemical reactions and pathways resulting in the breakdown of dUDP, deoxyuridine (5'-)diphosphate.	tmpzr1t_l9r_go_relaxed.owl	dUDP breakdown|dUDP degradation|dUDP catabolism													biological_process											owl:Class	
GO:0009198	biolink:NamedThing	pyrimidine deoxyribonucleoside diphosphate catabolic process	The chemical reactions and pathways resulting in the breakdown of pyrimidine deoxynucleoside diphosphate, a compound consisting of a pyrimidine base linked to a deoxyribose sugar esterified with diphosphate on the sugar.	tmpzr1t_l9r_go_relaxed.owl	pyrimidine deoxyribonucleoside diphosphate breakdown|pyrimidine deoxyribonucleoside diphosphate catabolism|pyrimidine deoxyribonucleoside diphosphate degradation													biological_process											owl:Class	
GO:0004185	biolink:NamedThing	serine-type carboxypeptidase activity	Catalysis of the hydrolysis of a single C-terminal amino acid residue from the C-terminus of a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine).	tmpzr1t_l9r_go_relaxed.owl	serine carboxypeptidase activity	https://github.com/geneontology/go-ontology/issues/19681			EC:3.4.16.-|Reactome:R-HSA-158251									molecular_function											owl:Class	
GO:0032541	biolink:NamedThing	cortical endoplasmic reticulum	A cortical network of highly dynamic tubules that are juxtaposed to the plasma membrane and undergo ring closure and tubule-branching movements.	tmpzr1t_l9r_go_relaxed.owl	ER-PM peripheral junction|peripheral endoplasmic reticulum|cortical ER|peripheral ER					The dynamic nature of the cortical ER and the movements it undergoes (branching and ring closure) has been shown in both yeast and mammalian cells, so appears highly conserved. (PMID:10931860)								cellular_component											owl:Class	
GO:0071782	biolink:NamedThing	endoplasmic reticulum tubular network	A subcompartment of the endoplasmic reticulum consisting of tubules having membranes with high curvature in cross-section.	tmpzr1t_l9r_go_relaxed.owl	ER tubular network							mah	2010-09-01T01:32:55Z					cellular_component											owl:Class	
GO:0042944	biolink:NamedThing	D-alanine transmembrane transporter activity	Enables the transfer of D-alanine from one side of a membrane to the other. D-alanine is the D-enantiomer of 2-aminopropanoic acid.	tmpzr1t_l9r_go_relaxed.owl	D-alanine transporter activity													molecular_function											owl:Class	
GO:0022858	biolink:NamedThing	alanine transmembrane transporter activity	Enables the transfer of alanine from one side of a membrane to the other. Alanine is 2-aminopropanoic acid.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0000336	biolink:NamedThing	positive regulation of transposition, DNA-mediated	Any process that activates or increases the frequency, rate or extent of DNA transposition.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of DNA transposition|upregulation of DNA transposition|up regulation of DNA transposition|stimulation of DNA transposition|positive regulation of DNA transposition|activation of DNA transposition													biological_process											owl:Class	
GO:0006144	biolink:NamedThing	purine nucleobase metabolic process	The chemical reactions and pathways involving purine nucleobases, one of the two classes of nitrogen-containing ring compounds found in DNA and RNA, which include adenine and guanine.	tmpzr1t_l9r_go_relaxed.owl	purine base metabolism|purine base metabolic process|purine metabolic process|purine metabolism													biological_process											owl:Class	
GO:0072521	biolink:NamedThing	purine-containing compound metabolic process	The chemical reactions and pathways involving a purine-containing compound, i.e. any compound that contains purine or a formal derivative thereof.	tmpzr1t_l9r_go_relaxed.owl	purine-containing compound metabolism|purine and derivative metabolic process							mah	2011-01-04T03:03:59Z					biological_process											owl:Class	
GO:1900191	biolink:NamedThing	negative regulation of single-species biofilm formation	Any process that stops, prevents or reduces the frequency, rate or extent of single-species biofilm formation.	tmpzr1t_l9r_go_relaxed.owl	down regulation of single-species biofilm formation|inhibition of single-species biofilm formation|downregulation of single-species biofilm formation|down-regulation of single-species biofilm formation							di	2012-03-19T12:42:13Z					biological_process											owl:Class	
GO:1904440	biolink:NamedThing	positive regulation of iron ion import across plasma membrane	Any process that activates or increases the frequency, rate or extent of iron ions import across plasma membrane.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of ferrous iron import across plasma membrane|upregulation of ferrous ion import into cell|activation of ferrous ion import into cell|up regulation of ferrous iron import across plasma membrane|activation of ferrous iron import across plasma membrane|up regulation of ferrous ion import into cell|positive regulation of ferrous iron import into cell|upregulation of ferrous iron import across plasma membrane|up-regulation of ferrous ion import into cell|positive regulation of ferrous ion import into cell|up-regulation of ferrous iron import across plasma membrane							rl	2015-07-06T13:50:04Z			GO:1903991		biological_process											owl:Class	
GO:0034761	biolink:NamedThing	positive regulation of iron ion transmembrane transport	Any process that activates or increases the frequency, rate or extent of the directed movement of iron ions from one side of a membrane to the other by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	stimulation of transmembrane iron ion transport|positive regulation of iron ion membrane transport|up-regulation of transmembrane iron ion transport|activation of transmembrane iron ion transport|positive regulation of transmembrane iron transport|upregulation of transmembrane iron ion transport|positive regulation of transmembrane iron ion transport|up regulation of transmembrane iron ion transport													biological_process											owl:Class	
GO:1900243	biolink:NamedThing	negative regulation of synaptic vesicle endocytosis	Any process that stops, prevents or reduces the frequency, rate or extent of synaptic vesicle endocytosis.	tmpzr1t_l9r_go_relaxed.owl	down regulation of synaptic vesicle endocytosis|down regulation of synaptic vesicle retrieval|downregulation of synaptic vesicle endocytosis|inhibition of synaptic vesicle retrieval|down-regulation of synaptic vesicle retrieval|inhibition of synaptic vesicle endocytosis|downregulation of synaptic vesicle retrieval|down-regulation of synaptic vesicle endocytosis|negative regulation of synaptic vesicle retrieval							rl	2012-03-28T01:40:36Z					biological_process											owl:Class	
GO:0033505	biolink:NamedThing	floor plate morphogenesis	The process in which the anatomical structure of the floor plate is generated and organized.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0072542	biolink:NamedThing	protein phosphatase activator activity	Binds to and increases the activity of a protein phosphatase, an enzyme which catalyzes of the removal of a phosphate group from a protein substrate molecule.	tmpzr1t_l9r_go_relaxed.owl	protein phosphatase 2 activator activity|protein phosphatase type 1 activator activity|protein phosphatase type 2A activator activity							mah	2010-09-10T03:39:56Z			GO:0071862|GO:0072543		molecular_function											owl:Class	
GO:0019888	biolink:NamedThing	protein phosphatase regulator activity	Binds to and modulates the activity of a protein phosphatase, an enzyme which catalyzes of the removal of a phosphate group from a protein substrate molecule.	tmpzr1t_l9r_go_relaxed.owl	protein phosphatase type 4, intrinsic regulator activity|protein phosphatase type 1 regulator activity|protein phosphatase type 2A, intrinsic regulator activity|protein phosphatase type 2B regulator activity|protein phosphatase 3 regulator activity|protein phosphatase 3, intrinsic regulator activity|protein phosphatase 2, intrinsic regulator activity|protein phosphatase type 2A regulator activity|protein phosphatase type 4 regulator activity|calcineurin, intrinsic regulator activity|protein phosphatase type 1, intrinsic regulator activity|protein phosphatase 2 regulator activity|calcineurin regulator activity|protein phosphatase type 2B, intrinsic regulator activity				Reactome:R-HSA-180038							GO:0008601|GO:0030362|GO:0030359|GO:0008599		molecular_function											owl:Class	
GO:0071019	biolink:NamedThing	U12-type post-mRNA release spliceosomal complex	A spliceosomal complex that is formed following the release of the spliced product from the post-spliceosomal complex and contains the excised intron and the U12, U5 and U6atac snRNPs.	tmpzr1t_l9r_go_relaxed.owl	AT-AC post-mRNA release spliceosomal complex|mammalian U12-type spliceosomal complex I|minor post-mRNA release spliceosomal complex							mah	2009-07-30T12:00:35Z					cellular_component											owl:Class	
GO:0071014	biolink:NamedThing	post-mRNA release spliceosomal complex	A spliceosomal complex that is formed following the release of the spliced product from the post-spliceosomal complex and contains the excised intron and three snRNPs, including U5.	tmpzr1t_l9r_go_relaxed.owl	mammalian spliceosomal complex I							mah	2009-07-30T12:00:35Z					cellular_component											owl:Class	
GO:0090290	biolink:NamedThing	positive regulation of osteoclast proliferation	Any process that increases the rate, frequency, or extent of the multiplication or reproduction of osteoclasts, resulting in the expansion of an osteoclast cell population.	tmpzr1t_l9r_go_relaxed.owl								tb	2010-02-18T03:11:03Z					biological_process											owl:Class	
GO:1903973	biolink:NamedThing	negative regulation of cellular response to macrophage colony-stimulating factor stimulus	Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to macrophage colony-stimulating factor stimulus.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of cellular response to M-CSF stimulus|down-regulation of cellular response to macrophage colony-stimulating factor stimulus|negative regulation of cellular response to macrophage colony-stimulating factor|downregulation of cellular response to macrophage colony-stimulating factor|downregulation of cellular response to M-CSF stimulus|inhibition of cellular response to macrophage colony-stimulating factor|down regulation of cellular response to macrophage colony-stimulating factor stimulus|downregulation of cellular response to macrophage colony-stimulating factor stimulus|down regulation of cellular response to M-CSF stimulus|inhibition of cellular response to M-CSF stimulus|negative regulation of cellular response to M-CSF stimulus|down regulation of cellular response to macrophage colony-stimulating factor|inhibition of cellular response to macrophage colony-stimulating factor stimulus|down-regulation of cellular response to macrophage colony-stimulating factor							nc	2015-03-02T14:50:20Z					biological_process											owl:Class	
GO:0000910	biolink:NamedThing	cytokinesis	The division of the cytoplasm and the plasma membrane of a cell and its partitioning into two daughter cells.	tmpzr1t_l9r_go_relaxed.owl	cytokinesis involved in cell cycle|cell cycle cytokinesis				Wikipedia:Cytokinesis	Note that this term should not be used for direct annotation. When annotating eukaryotic species, mitotic or meiotic cytokinesis should always be specified for manual annotation and for prokaryotic species use 'FtsZ-dependent cytokinesis ; GO:0043093' or Cdv-dependent cytokinesis ; GO:0061639.  Also, note that cytokinesis does not necessarily result in physical separation and detachment of the two daughter cells from each other.						GO:0007104|GO:0033205|GO:0016288		biological_process											owl:Class	
GO:0097044	biolink:NamedThing	histone H3-K56 acetylation in response to DNA damage	The modification of histone H3 by the addition of an acetyl group to a lysine residue at position 56 of the histone as a result of the detection of DNA damage within a cell.	tmpzr1t_l9r_go_relaxed.owl								pr	2011-04-19T05:22:54Z					biological_process											owl:Class	
GO:0097043	biolink:NamedThing	histone H3-K56 acetylation	The modification of histone H3 by the addition of an acetyl group to a lysine residue at position 56 of the histone.	tmpzr1t_l9r_go_relaxed.owl								pr	2011-04-19T05:18:29Z					biological_process											owl:Class	
GO:0099533	biolink:NamedThing	positive regulation of presynaptic cytosolic calcium concentration	Any process that increases the concentration of calcium ions in the presynaptic cytosol.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0007204	biolink:NamedThing	positive regulation of cytosolic calcium ion concentration	Any process that increases the concentration of calcium ions in the cytosol.	tmpzr1t_l9r_go_relaxed.owl	elevation of calcium ion concentration in cytosol|cytosolic calcium ion concentration elevation|elevation of cytosolic calcium ion concentration|elevation of calcium ion concentration in cytoplasm|elevation of cytoplasmic calcium ion concentration|cytoplasmic calcium ion concentration elevation													biological_process											owl:Class	
GO:0002906	biolink:NamedThing	negative regulation of mature B cell apoptotic process	Any process that stops, prevents, or reduces the frequency, rate, or extent of mature B cell apoptotic process.	tmpzr1t_l9r_go_relaxed.owl	downregulation of mature B cell apoptosis|down-regulation of mature B cell apoptosis|inhibition of mature B cell apoptosis|down regulation of mature B cell apoptosis|negative regulation of mature B cell apoptosis													biological_process											owl:Class	
GO:0002905	biolink:NamedThing	regulation of mature B cell apoptotic process	Any process that modulates the frequency, rate, or extent of mature B cell apoptotic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of mature B cell apoptosis													biological_process											owl:Class	
GO:0019255	biolink:NamedThing	glucose 1-phosphate metabolic process	The chemical reactions and pathways involving glucose 1-phosphate, a monophosphorylated derivative of glucose with the phosphate group attached to C-1.	tmpzr1t_l9r_go_relaxed.owl	glucose 1-phosphate metabolism|glucose 1-phosphate utilization				MetaCyc:GLUCOSE1PMETAB-PWY							GO:0006008		biological_process											owl:Class	
GO:0046308	biolink:NamedThing	Z-phenylacetaldoxime catabolic process	The chemical reactions and pathways resulting in the breakdown of Z-phenylacetaldoxime, a member of the glucosinolate group of compounds.	tmpzr1t_l9r_go_relaxed.owl	Z-phenylacetaldoxime catabolism|Z-phenylacetaldoxime degradation|Z-phenylacetaldoxime breakdown													biological_process											owl:Class	
GO:0018983	biolink:NamedThing	Z-phenylacetaldoxime metabolic process	The chemical reactions and pathways involving Z-phenylacetaldoxime, a member of the glucosinolate group of compounds, a class of natural products that are gaining increasing interest as cancer-preventing agents and crop protectants.	tmpzr1t_l9r_go_relaxed.owl	Z-phenylacetaldoxime metabolism				UM-BBD_pathwayID:pao									biological_process											owl:Class	
GO:0019400	biolink:NamedThing	alditol metabolic process	The chemical reactions and pathways involving alditols, any polyhydric alcohol derived from the acyclic form of a monosaccharide by reduction of its aldehyde or keto group to an alcoholic group.	tmpzr1t_l9r_go_relaxed.owl	alditol metabolism													biological_process											owl:Class	
GO:0019751	biolink:NamedThing	polyol metabolic process	The chemical reactions and pathways involving a polyol, any alcohol containing three or more hydroxyl groups attached to saturated carbon atoms.	tmpzr1t_l9r_go_relaxed.owl	polyhydric alcohol metabolic process|polyol metabolism													biological_process											owl:Class	
GO:0072134	biolink:NamedThing	nephrogenic mesenchyme morphogenesis	The process in which the anatomical structures of a nephrogenic mesenchymal tissue are generated and organized. Nephrogenic mesenchyme is the tissue made up of loosely connected mesenchymal cells in the nephron.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-02-22T02:21:16Z					biological_process											owl:Class	
GO:0072131	biolink:NamedThing	kidney mesenchyme morphogenesis	The process in which the anatomical structures of a kidney mesenchymal tissue are generated and organized. Kidney mesenchyme is the tissue made up of loosely connected mesenchymal cells in the kidney.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-02-22T02:16:43Z					biological_process											owl:Class	
GO:0034681	biolink:NamedThing	integrin alpha11-beta1 complex	An integrin complex that comprises one alpha11 subunit and one beta1 subunit.	tmpzr1t_l9r_go_relaxed.owl	alpha11-beta1 integrin complex|ITGA11-ITGB1 complex													cellular_component											owl:Class	
GO:0033313	biolink:NamedThing	meiotic cell cycle checkpoint signaling	A signaling process that contributes to a meiotic cell cycle checkpoint that ensures accurate chromosome replication and segregation by preventing progression through a meiotic cell cycle until conditions are suitable for the cell to proceed to the next stage.	tmpzr1t_l9r_go_relaxed.owl	signal transduction involved in meiotic cell cycle checkpoint|meiotic cell cycle checkpoint	https://github.com/geneontology/go-ontology/issues/20935										GO:0072411		biological_process											owl:Class	
GO:0000075	biolink:NamedThing	cell cycle checkpoint signaling	A signaling process that controls cell cycle progression by monitoring the integrity of specific cell cycle events. A cell cycle checkpoint begins with detection of deficiencies or defects and ends with signal transduction.	tmpzr1t_l9r_go_relaxed.owl	G2/M checkpoint|signal transduction involved in cell cycle checkpoint|cell cycle checkpoint|G1/S checkpoint|signal transduction involved in G2/M transition checkpoint|G1/S transition checkpoint|G2/M transition checkpoint	https://github.com/geneontology/go-ontology/issues/20935			Wikipedia:Cell_cycle_checkpoint	This term should not be used in direct manual annotation as it should always be possible to minimally designate mitotic or meiotic checkpoint, and usually to additionally specify the checkpoint (i.e mitotic spindle assembly checkpoint, mitotic DNA damage checkpoint etc). Note also that the effector processes are not part of the checkpoint but are positively regulated by the checkpoint signaling and should not be annotated here.						GO:0071779|GO:0072395|GO:0031576|GO:0072407|GO:0072404		biological_process											owl:Class	
GO:0005222	biolink:NamedThing	intracellular cAMP-activated cation channel activity	Enables the transmembrane transfer of a cation by a channel that opens when intracellular cAMP has been bound by the channel complex or one of its constituent parts.	tmpzr1t_l9r_go_relaxed.owl	intracellular adenosine 3',5'-cyclophosphate activated cation channel activity|intracellular cAMP activated cation channel activity|intracellular 3',5' cAMP activated cation channel activity|HCN channel activity|intracellular 3',5'-cAMP activated cation channel activity|hyperpolarization-activated cyclic nucleotide-gated channel activity|intracellular cyclic AMP activated cation channel activity													molecular_function											owl:Class	
GO:0005221	biolink:NamedThing	intracellular cyclic nucleotide activated cation channel activity	Enables the transmembrane transfer of a cation by a channel that opens when intracellular cyclic nucleotide has been bound by the channel complex or one of its constituent parts.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-2514867									molecular_function											owl:Class	
GO:1902267	biolink:NamedThing	regulation of polyamine transmembrane transport	Any process that modulates the frequency, rate or extent of polyamine transmembrane transport.	tmpzr1t_l9r_go_relaxed.owl								mcc	2013-06-28T21:34:36Z					biological_process											owl:Class	
GO:0140314	biolink:NamedThing	calcium ion sequestering activity	The selective interaction of a protein with a calcium ion to prevent it from interacting with other partners or inhibiting its localization to other areas of the cell.	tmpzr1t_l9r_go_relaxed.owl								pg	2019-03-28T10:07:18Z					molecular_function											owl:Class	
GO:1905691	biolink:NamedThing	lipid droplet disassembly	The disaggregation of a lipid particle into its constituent components.	tmpzr1t_l9r_go_relaxed.owl	lipid body disassembly|lipid droplet reserve breakdown|lipid particle disassembly|adiposome disassembly							pr	2016-11-14T13:39:06Z					biological_process											owl:Class	
GO:1901046	biolink:NamedThing	positive regulation of oviposition	Any process that activates or increases the frequency, rate or extent of oviposition.	tmpzr1t_l9r_go_relaxed.owl	activation of egg-laying|upregulation of egg laying|up regulation of egg-laying|positive regulation of egg-laying|up regulation of oviposition|up-regulation of oviposition|upregulation of oviposition|activation of egg laying|activation of oviposition|upregulation of egg-laying|positive regulation of egg laying|up regulation of egg laying|up-regulation of egg laying|up-regulation of egg-laying							kmv	2012-06-27T06:20:20Z					biological_process											owl:Class	
GO:0046776	biolink:NamedThing	suppression by virus of host antigen processing and presentation of peptide antigen via MHC class I	Any viral process that inhibits a host antigen-presenting cell expressing a peptide antigen on its cell surface in association with an MHC class I transmembrane protein complex. One mechanism of suppression is by direct inhibition of host tapasin, a type I transmembrane protein essential for the optimal expression of stable MHC class I molecules on the host cell surface. By inhibiting host tapasin activity, viruses can prevent presentation of their antigens at the cell surface, and thereby evade the host anti-viral immune response.	tmpzr1t_l9r_go_relaxed.owl	suppression by virus of host MHC class I cell surface presentation|inhibition of host MHC class I molecule presentation by virus|suppression by virus of MHC class I cell surface presentation in host|suppression by virus of host tapasin activity|negative regulation by virus of MHC class I cell surface presentation	https://github.com/geneontology/go-ontology/issues/22150										GO:0039591		biological_process											owl:Class	
GO:0060967	biolink:NamedThing	negative regulation of gene silencing by RNA	Any process that decreases the rate, frequency, or extent of gene silencing by RNA. Gene silencing by RNA is the process in which RNA molecules inactivate expression of target genes.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-10-05T03:21:05Z					biological_process											owl:Class	
GO:0060257	biolink:NamedThing	negative regulation of flocculation	Any process that decreases the rate, frequency or extent of the non-sexual aggregation of single-celled organisms.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of coflocculation	https://github.com/geneontology/go-ontology/issues/20192|https://github.com/geneontology/go-ontology/issues/18785						al	2012-07-12T07:17:11Z			GO:1901134		biological_process											owl:Class	
GO:0061114	biolink:NamedThing	branching involved in pancreas morphogenesis	The process in which the branches of the pancreas are generated and organized.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-05-05T12:03:04Z					biological_process											owl:Class	
GO:2000512	biolink:NamedThing	negative regulation of granzyme A production	Any process that stops, prevents or reduces the frequency, rate or extent of granzyme A production.	tmpzr1t_l9r_go_relaxed.owl								ebc	2011-03-22T10:31:32Z					biological_process											owl:Class	
GO:0018482	biolink:NamedThing	4-formylbenzenesulfonate dehydrogenase activity	Catalysis of the reaction: 4-formylbenzenesulfonate + H(2)O + NAD(+) = 4-sulfobenzoate + 2 H(+) + NADH.	tmpzr1t_l9r_go_relaxed.owl	toluene-sulfonate aldehyde dehydrogenase activity|4-formylbenzenesulfonate:NAD+ oxidoreductase activity|4-formylbenzenesulphonate dehydrogenase activity				KEGG_REACTION:R05272|RHEA:18833|UM-BBD_reactionID:r0292|EC:1.2.1.62|MetaCyc:1.2.1.62-RXN									molecular_function											owl:Class	
GO:0071248	biolink:NamedThing	cellular response to metal ion	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a metal ion stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to heavy metal|cellular response to metal							mah	2009-12-03T02:46:31Z					biological_process											owl:Class	
GO:0010038	biolink:NamedThing	response to metal ion	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a metal ion stimulus.	tmpzr1t_l9r_go_relaxed.owl	heavy metal sensitivity/resistance|response to heavy metal|response to metal													biological_process											owl:Class	
GO:1900127	biolink:NamedThing	positive regulation of hyaluronan biosynthetic process	Any process that activates or increases the frequency, rate or extent of hyaluronan biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of hyaluronan formation|activation of hyaluronan anabolism|activation of hyaluronan formation|activation of hyaluronan biosynthetic process|up-regulation of hyaluronan biosynthetic process|upregulation of hyaluronan formation|up regulation of hyaluronan synthesis|up regulation of hyaluronan formation|activation of hyaluronan synthesis|upregulation of hyaluronan biosynthesis|upregulation of hyaluronan anabolism|up-regulation of hyaluronan anabolism|up regulation of hyaluronan biosynthesis|up regulation of hyaluronan biosynthetic process|up-regulation of hyaluronan biosynthesis|up regulation of hyaluronan anabolism|positive regulation of hyaluronan formation|positive regulation of hyaluronan anabolism|positive regulation of hyaluronan synthesis|up-regulation of hyaluronan synthesis|positive regulation of hyaluronan biosynthesis|upregulation of hyaluronan synthesis|activation of hyaluronan biosynthesis|upregulation of hyaluronan biosynthetic process							yaf	2012-02-23T01:09:33Z					biological_process											owl:Class	
GO:0045913	biolink:NamedThing	positive regulation of carbohydrate metabolic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving carbohydrate.	tmpzr1t_l9r_go_relaxed.owl	up regulation of carbohydrate metabolic process|up-regulation of carbohydrate metabolic process|activation of carbohydrate metabolic process|upregulation of carbohydrate metabolic process|stimulation of carbohydrate metabolic process|positive regulation of carbohydrate metabolism													biological_process											owl:Class	
GO:0102366	biolink:NamedThing	7-beta-hydroxytaxusin 2-alpha-hydroxylase activity	Catalysis of the reaction: 7-beta-hydroxytaxusin + NADPH + O2 + H+ = 2alpha, 7-beta-dihydroxytaxusin + NADP + H2O.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-13487									molecular_function											owl:Class	
GO:1901946	biolink:NamedThing	miltiradiene biosynthetic process	The chemical reactions and pathways resulting in the formation of miltiradiene.	tmpzr1t_l9r_go_relaxed.owl	miltiradiene anabolism|miltiradiene biosynthesis|miltiradiene synthesis|miltiradiene formation							ms	2013-02-18T15:50:32Z					biological_process											owl:Class	
GO:0042647	biolink:NamedThing	proplastid nucleoid	The region of a proplastid to which the DNA is confined.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0009295	biolink:NamedThing	nucleoid	The region of a virus, bacterial cell, mitochondrion or chloroplast to which the nucleic acid is confined.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Nucleoid									cellular_component											owl:Class	
GO:0098555	biolink:NamedThing	lumenal side of rough endoplasmic reticulum membrane	The side (leaflet) of the rough endoplasmic reticulum membrane that faces the lumen.	tmpzr1t_l9r_go_relaxed.owl								dos	2013-12-03T12:13:24Z					cellular_component											owl:Class	
GO:0098553	biolink:NamedThing	lumenal side of endoplasmic reticulum membrane	The side (leaflet) of the plasma membrane that faces the lumen.	tmpzr1t_l9r_go_relaxed.owl								dos	2013-12-03T12:08:37Z					cellular_component											owl:Class	
GO:0016558	biolink:NamedThing	protein import into peroxisome matrix	The import of proteins into the peroxisomal matrix. A peroxisome targeting signal (PTS) binds to a soluble receptor protein in the cytosol, and the resulting complex then binds to a receptor protein in the peroxisome membrane and is imported. The cargo protein is then released into the peroxisome matrix.	tmpzr1t_l9r_go_relaxed.owl	peroxisome matrix protein import|protein transport to peroxisome matrix													biological_process											owl:Class	
GO:0044743	biolink:NamedThing	protein transmembrane import into intracellular organelle	The directed movement of proteins into an intracellular organelle, across a membrane.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-11-07T15:37:36Z					biological_process											owl:Class	
GO:0071736	biolink:NamedThing	IgG immunoglobulin complex, circulating	A protein complex composed of two identical immunoglobulin heavy chains of an IgG isotype and two identical immunoglobulin light chains, held together by disulfide bonds, and present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.	tmpzr1t_l9r_go_relaxed.owl	IgG3 antibody|IgG2a antibody|IgG2 antibody|IgG2c antibody|IgG1 antibody|IgG antibody|IgG4 antibody|IgG2b antibody					Note that an IgG immunoglobulin complex has the function of antigen binding if a suitable antigen is available. Also, IgG isotypes vary by species.		mah	2010-03-24T01:44:53Z					cellular_component											owl:Class	
GO:0071735	biolink:NamedThing	IgG immunoglobulin complex	A protein complex composed of two identical immunoglobulin heavy chains of an IgG isotype and two identical immunoglobulin light chains, held together by disulfide bonds. An IgG immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.	tmpzr1t_l9r_go_relaxed.owl	IgG2c|IgG3|IgG4|IgG2a|IgG2b|IgG1|IgG2					Note that an IgG immunoglobulin complex has the function of antigen binding if a suitable antigen is available. Also, IgG isotypes vary by species.		mah	2010-03-24T01:44:53Z					cellular_component											owl:Class	
GO:0047174	biolink:NamedThing	putrescine N-hydroxycinnamoyltransferase activity	Catalysis of the reaction: caffeoyl-CoA + putrescine = N-caffeoylputrescine + CoA + H(+).	tmpzr1t_l9r_go_relaxed.owl	caffeoyl-CoA putrescine N-caffeoyl transferase activity|putrescine hydroxycinnamoyltransferase activity|hydroxycinnamoyl-CoA:putrescine hydroxycinnamoyltransferase activity|caffeoyl-CoA:putrescine N-(3,4-dihydroxycinnamoyl)transferase activity|putrescine hydroxycinnamoyl transferase activity|PHT				KEGG_REACTION:R01944|MetaCyc:2.3.1.138-RXN|EC:2.3.1.138|RHEA:12436									molecular_function											owl:Class	
GO:0050734	biolink:NamedThing	hydroxycinnamoyltransferase activity	Catalysis of the transfer of a hydroxycinnamoyl group to an acceptor molecule.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0012509	biolink:NamedThing	inter-Golgi transport vesicle membrane	The lipid bilayer surrounding a vesicle transporting substances within the Golgi.	tmpzr1t_l9r_go_relaxed.owl	inter-Golgi transport constitutive secretory pathway transport vesicle membrane													cellular_component											owl:Class	
GO:0030663	biolink:NamedThing	COPI-coated vesicle membrane	The lipid bilayer surrounding a COPI-coated vesicle.	tmpzr1t_l9r_go_relaxed.owl	COPI coated vesicle membrane													cellular_component											owl:Class	
GO:0080041	biolink:NamedThing	ADP-ribose pyrophosphohydrolase activity	Catalysis of the reaction: ADP-ribose + H2O = AMP + ribose-1-phosphate.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0045241	biolink:NamedThing	cytosolic alpha-ketoglutarate dehydrogenase complex	Cytosolic complex that possesses alpha-ketoglutarate dehydrogenase activity.	tmpzr1t_l9r_go_relaxed.owl	2-oxoglutarate dehydrogenase complex													cellular_component											owl:Class	
GO:0045240	biolink:NamedThing	dihydrolipoyl dehydrogenase complex	A protein complex that possesses alpha-ketoglutarate dehydrogenase activity.	tmpzr1t_l9r_go_relaxed.owl	2-oxoglutarate dehydrogenase complex|alpha-ketoglutarate dehydrogenase complex													cellular_component											owl:Class	
GO:1903372	biolink:NamedThing	negative regulation of endoplasmic reticulum tubular network organization	Any process that stops, prevents or reduces the frequency, rate or extent of endoplasmic reticulum tubular network organization.	tmpzr1t_l9r_go_relaxed.owl	inhibition of endoplasmic reticulum tubular network organization|downregulation of ER tubular network organisation|negative regulation of endoplasmic reticulum tubular network organisation|down regulation of endoplasmic reticulum tubular network organization|negative regulation of ER tubular network organization|down regulation of ER tubular network organisation|down-regulation of endoplasmic reticulum tubular network organization|downregulation of endoplasmic reticulum tubular network organisation|downregulation of ER tubular network organization|inhibition of ER tubular network organisation|inhibition of ER tubular network organization|down regulation of endoplasmic reticulum tubular network organisation|down-regulation of endoplasmic reticulum tubular network organisation|down-regulation of ER tubular network organisation|downregulation of endoplasmic reticulum tubular network organization|down-regulation of ER tubular network organization|down regulation of ER tubular network organization|inhibition of endoplasmic reticulum tubular network organisation|negative regulation of ER tubular network organisation							als	2014-08-22T11:01:23Z					biological_process											owl:Class	
GO:1900348	biolink:NamedThing	regulation of methane biosynthetic process from methylamine	Any process that modulates the frequency, rate or extent of methane biosynthetic process from methylamine.	tmpzr1t_l9r_go_relaxed.owl								tt	2012-04-06T02:11:54Z					biological_process											owl:Class	
GO:0102709	biolink:NamedThing	S-adenosyl-L-methionine:N,N-dimethyl-beta-alanine N-methyltransferase activity	Catalysis of the reaction: N,N-dimethyl-beta-alanine + S-adenosyl-L-methionine  = H+ + beta-alanine betaine + S-adenosyl-L-homocysteine.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-6464									molecular_function											owl:Class	
GO:1904020	biolink:NamedThing	regulation of G protein-coupled receptor internalization	Any process that modulates the frequency, rate or extent of G protein-coupled receptor internalization.	tmpzr1t_l9r_go_relaxed.owl	regulation of G-protein-coupled receptor internalization							pga	2015-03-10T17:10:45Z					biological_process											owl:Class	
GO:0140498	biolink:NamedThing	mannan polymerase I complex	A complex with alpha-(1->6)-mannosyltransferase activity, located in the cis Golgi membrane; adds mannan to N-linked glycans on proteins as part of the priming and elongation of alpha 1,6-linked Man backbone. In S. cerevisiae, contains Mnn9p and Van1p.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/19817						pg	2020-07-22T14:34:23Z					cellular_component											owl:Class	
GO:0000136	biolink:NamedThing	mannan polymerase complex	A protein complex with alpha-(1->6)-mannosyltransferase activity, located in the cis Golgi membrane; adds mannan to N-linked glycans on proteins.	tmpzr1t_l9r_go_relaxed.owl	alpha-1,6-mannosyltransferase complex	https://github.com/geneontology/go-ontology/issues/19817												cellular_component											owl:Class	
GO:0050258	biolink:NamedThing	riboflavinase activity	Catalysis of the reaction: H(2)O + H(+) + riboflavin = D-ribitol + lumichrome.	tmpzr1t_l9r_go_relaxed.owl	riboflavin hydrolase activity				EC:3.5.99.1|MetaCyc:RIBOFLAVINASE-RXN|KEGG_REACTION:R01732|RHEA:11408									molecular_function											owl:Class	
GO:0043552	biolink:NamedThing	positive regulation of phosphatidylinositol 3-kinase activity	Any process that activates or increases the frequency, rate or extent of phosphatidylinositol 3-kinase activity.	tmpzr1t_l9r_go_relaxed.owl	upregulation of phosphatidylinositol 3-kinase activity|up-regulation of phosphatidylinositol 3-kinase activity|stimulation of phosphatidylinositol 3-kinase activity|positive regulation of phosphoinositide 3-kinase activity|up regulation of phosphatidylinositol 3-kinase activity|activation of phosphatidylinositol 3-kinase activity													biological_process											owl:Class	
GO:0050577	biolink:NamedThing	GDP-L-fucose synthase activity	Catalysis of the reaction: GDP-L-fucose + NAD+ = GDP-4-dehydro-6-deoxy-D-mannose + NADH + H+.	tmpzr1t_l9r_go_relaxed.owl	GDP-fucose synthetase activity|GDP-4-keto-6-deoxy-D-mannose-3,5-epimerase-4-reductase activity|GDP-L-fucose:NADP+ 4-oxidoreductase (3,5-epimerizing)				Reactome:R-HSA-6787642|RHEA:18885|EC:1.1.1.271|MetaCyc:1.1.1.271-RXN									molecular_function											owl:Class	
GO:1902169	biolink:NamedThing	cellular response to catechin	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a catechin stimulus.	tmpzr1t_l9r_go_relaxed.owl								rjd	2013-05-22T17:35:40Z					biological_process											owl:Class	
GO:1902168	biolink:NamedThing	response to catechin	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a catechin stimulus.	tmpzr1t_l9r_go_relaxed.owl								rjd	2013-05-22T17:35:35Z					biological_process											owl:Class	
GO:0032139	biolink:NamedThing	dinucleotide insertion or deletion binding	Binding to a double-stranded DNA region containing a dinucleotide insertion or deletion.	tmpzr1t_l9r_go_relaxed.owl	dinucleotide insertion binding													molecular_function											owl:Class	
GO:0032135	biolink:NamedThing	DNA insertion or deletion binding	Binding to a double-stranded DNA region containing an insertion or a deletion.	tmpzr1t_l9r_go_relaxed.owl	DNA insertion binding|insertion binding													molecular_function											owl:Class	
GO:0032805	biolink:NamedThing	positive regulation of low-density lipoprotein particle receptor catabolic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of low-density lipoprotein particle receptors.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of low-density lipoprotein receptor catabolism|positive regulation of low-density lipoprotein receptor catabolic process|stimulation of low-density lipoprotein receptor catabolic process|activation of low-density lipoprotein receptor catabolic process|up regulation of low-density lipoprotein receptor catabolic process|positive regulation of low-density lipoprotein receptor breakdown|positive regulation of low-density lipoprotein receptor degradation|up-regulation of low-density lipoprotein receptor catabolic process|upregulation of low-density lipoprotein receptor catabolic process													biological_process											owl:Class	
GO:0044829	biolink:NamedThing	positive regulation by host of viral genome replication	A process in which a host organism activates or increases the frequency, rate or extent of  viral genome replication.	tmpzr1t_l9r_go_relaxed.owl								jl	2014-02-06T11:35:07Z					biological_process											owl:Class	
GO:0044794	biolink:NamedThing	positive regulation by host of viral process	A process in which a host organism activates or increases the frequency, rate or extent of the release of a process being mediated by a virus with which it is infected.	tmpzr1t_l9r_go_relaxed.owl								jl	2013-06-06T11:33:51Z					biological_process											owl:Class	
GO:0009209	biolink:NamedThing	pyrimidine ribonucleoside triphosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of pyrimidine ribonucleoside triphosphate, a compound consisting of a pyrimidine base linked to a ribose sugar esterified with triphosphate on the sugar.	tmpzr1t_l9r_go_relaxed.owl	pyrimidine ribonucleoside triphosphate anabolism|pyrimidine ribonucleoside triphosphate biosynthesis|pyrimidine ribonucleoside triphosphate formation|pyrimidine ribonucleoside triphosphate synthesis													biological_process											owl:Class	
GO:0009208	biolink:NamedThing	pyrimidine ribonucleoside triphosphate metabolic process	The chemical reactions and pathways involving pyrimidine ribonucleoside triphosphate, a compound consisting of a pyrimidine base linked to a ribose sugar esterified with triphosphate on the sugar.	tmpzr1t_l9r_go_relaxed.owl	pyrimidine ribonucleoside triphosphate metabolism													biological_process											owl:Class	
GO:0032882	biolink:NamedThing	regulation of chitin metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving chitin.	tmpzr1t_l9r_go_relaxed.owl	regulation of chitin metabolism													biological_process											owl:Class	
GO:0090668	biolink:NamedThing	endothelial cell chemotaxis to vascular endothelial growth factor	The directed movement of an endothelial cell in response to the presence of vascular endothelial growth factor (VEGF).	tmpzr1t_l9r_go_relaxed.owl								tb	2015-12-15T11:31:43Z					biological_process											owl:Class	
GO:0090667	biolink:NamedThing	cell chemotaxis to vascular endothelial growth factor	The directed movement of a motile cell in response to the presence of vascular endothelial growth factor (VEGF).	tmpzr1t_l9r_go_relaxed.owl								tb	2015-12-15T11:27:12Z					biological_process											owl:Class	
GO:1900657	biolink:NamedThing	positive regulation of diorcinol biosynthetic process	Any process that activates or increases the frequency, rate or extent of diorcinol biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	upregulation of diorcinol anabolism|up-regulation of diorcinol biosynthesis|positive regulation of diorcinol formation|activation of diorcinol synthesis|positive regulation of diorcinol anabolism|positive regulation of diorcinol synthesis|upregulation of diorcinol formation|upregulation of diorcinol synthesis|up regulation of diorcinol synthesis|activation of diorcinol biosynthesis|up-regulation of diorcinol formation|activation of diorcinol biosynthetic process|upregulation of diorcinol biosynthetic process|activation of diorcinol formation|up-regulation of diorcinol anabolism|up regulation of diorcinol formation|up regulation of diorcinol biosynthetic process|up regulation of diorcinol biosynthesis|up-regulation of diorcinol synthesis|upregulation of diorcinol biosynthesis|activation of diorcinol anabolism|up-regulation of diorcinol biosynthetic process|positive regulation of diorcinol biosynthesis|up regulation of diorcinol anabolism							di	2012-05-22T04:09:08Z					biological_process											owl:Class	
GO:0050831	biolink:NamedThing	male-specific defense response to bacterium	A set of reactions, specific to males, that are triggered in response to the presence of a bacterium that act to protect the cell or organism.	tmpzr1t_l9r_go_relaxed.owl	male-specific defence response to bacterium|male-specific defence response to bacteria|male-specific defense response to bacteria|male-specific antibacterial peptide activity													biological_process											owl:Class	
GO:0042742	biolink:NamedThing	defense response to bacterium	Reactions triggered in response to the presence of a bacterium that act to protect the cell or organism.	tmpzr1t_l9r_go_relaxed.owl	defense response to bacteria|defense response to bacterium, incompatible interaction|resistance response to pathogenic bacteria|defence response to bacteria|resistance response to pathogenic bacterium|antibacterial peptide activity|defence response to bacterium											GO:0042830|GO:0009816		biological_process											owl:Class	
GO:0051974	biolink:NamedThing	negative regulation of telomerase activity	Any process that stops or reduces the activity of the enzyme telomerase, which catalyzes of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).	tmpzr1t_l9r_go_relaxed.owl	downregulation of telomerase activity|down regulation of telomerase activity|down-regulation of telomerase activity|telomerase inhibitor|inhibition of telomerase activity													biological_process											owl:Class	
GO:0033373	biolink:NamedThing	maintenance of protease location in mast cell secretory granule	A process in which a protease is maintained in a secretory granule in a mast cell and prevented from moving elsewhere.	tmpzr1t_l9r_go_relaxed.owl	maintenance of protease localization in mast cell secretory granule|mast cell protease retention													biological_process											owl:Class	
GO:1901668	biolink:NamedThing	regulation of superoxide dismutase activity	Any process that modulates the frequency, rate or extent of superoxide dismutase activity.	tmpzr1t_l9r_go_relaxed.owl	regulation of cuprein|regulation of Cu,Zn-SOD|regulation of hepatocuprein|regulation of superoxide dismutase I|regulation of erythrocuprein|regulation of Mn, Fe superoxide dismutase|regulation of Cu-Zn superoxide dismutase activity|regulation of hemocuprein|regulation of superoxide dismutase II|regulation of SOD-1|regulation of manganese superoxide dismutase activity|regulation of nickel superoxide oxidoreductase|regulation of SODS|regulation of Mn-SOD|regulation of SOD-3|regulation of cytocuprein|regulation of nickel superoxide dismutase activity|regulation of copper, zinc superoxide dismutase activity|regulation of SOD-2|regulation of SOD|regulation of ferrisuperoxide dismutase activity|regulation of manganese superoxide oxidoreductase|regulation of zinc superoxide oxidoreductase|regulation of superoxide:superoxide oxidoreductase activity|regulation of Fe-SOD|regulation of iron superoxide oxidoreductase|regulation of iron superoxide dismutase activity|regulation of SOD-4|regulation of SODF							tb	2012-11-21T20:46:42Z					biological_process											owl:Class	
GO:0032681	biolink:NamedThing	regulation of lymphotoxin A production	Any process that modulates the frequency, rate, or extent of lymphotoxin A production.	tmpzr1t_l9r_go_relaxed.owl	regulation of LTA production|regulation of tumor necrosis factor-beta production|regulation of lymphotoxin-alpha production|regulation of TNF-beta production|regulation of lymphotoxin A biosynthetic process											GO:0043016		biological_process											owl:Class	
GO:0080067	biolink:NamedThing	4-methylthiobutyl-desulfoglucosinolate sulfotransferase activity	Catalysis of the reaction: 4-methylthiobutyl-desulfoglucosinolate + 3'-phosphoadenosine 5'-phosphosulfate = 4-methylthiobutyl-glucosinolate + adenosine 3',5'-bisphosphate.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXNQT-4329			dhl	2009-04-13T04:05:53Z					molecular_function											owl:Class	
GO:0047364	biolink:NamedThing	desulfoglucosinolate sulfotransferase activity	Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + desulfoglucotropeolin = adenosine 3',5'-diphosphate + glucotropeolin + H(+).	tmpzr1t_l9r_go_relaxed.owl	3'-phosphoadenosine-5'-phosphosulfate:desulfoglucosinolate sulfotransferase activity|PAPS-desulfoglucosinolate sulfotransferase activity|3'-phosphoadenylyl-sulfate:desulfoglucosinolate sulfotransferase activity|desulphoglucosinolate sulphotransferase activity				KEGG_REACTION:R03214|MetaCyc:2.8.2.24-RXN|EC:2.8.2.24|RHEA:20281									molecular_function											owl:Class	
GO:0019347	biolink:NamedThing	GDP-alpha-D-mannosylchitobiosyldiphosphodolichol biosynthetic process	The chemical reactions and pathways resulting in the formation of GDP-alpha-D-mannosylchitobiosyldiphosphodolichol, a substance composed of mannosylchitobiosyldiphosphodolichol in glycosidic linkage with guanosine diphosphate.	tmpzr1t_l9r_go_relaxed.owl	GDP-alpha-D-mannosylchitobiosyldiphosphodolichol formation|GDP-alpha-D-mannosylchitobiosyldiphosphodolichol anabolism|GDP-alpha-D-mannosylchitobiosyldiphosphodolichol biosynthesis|GDP-alpha-D-mannosylchitobiosyldiphosphodolichol synthesis				MetaCyc:MANNOSYL-CHITO-DOLICHOL-BIOSYNTHESIS									biological_process											owl:Class	
GO:1904073	biolink:NamedThing	regulation of trophectodermal cell proliferation	Any process that modulates the frequency, rate or extent of trophectodermal cell proliferation.	tmpzr1t_l9r_go_relaxed.owl	regulation of trophectoderm cell proliferation							tb	2015-03-20T16:55:56Z					biological_process											owl:Class	
GO:0051656	biolink:NamedThing	establishment of organelle localization	The directed movement of an organelle to a specific location.	tmpzr1t_l9r_go_relaxed.owl	establishment of organelle localisation													biological_process											owl:Class	
GO:0150012	biolink:NamedThing	positive regulation of neuron projection arborization	Any process that activates or increases the frequency, rate or extent of the process in which the anatomical structures of a neuron projection are generated and organized into branches.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of neurite arborization|positive regulation of neuron projection branching|positive regulation of neurite branching							bc	2017-12-13T16:46:57Z					biological_process											owl:Class	
GO:1901045	biolink:NamedThing	negative regulation of oviposition	Any process that stops, prevents or reduces the frequency, rate or extent of oviposition.	tmpzr1t_l9r_go_relaxed.owl	inhibition of egg laying|downregulation of egg-laying|down regulation of egg-laying|down-regulation of egg-laying|inhibition of oviposition|downregulation of egg laying|downregulation of oviposition|negative regulation of egg laying|down regulation of egg laying|down-regulation of egg laying|inhibition of egg-laying|down-regulation of oviposition|down regulation of oviposition|negative regulation of egg-laying							kmv	2012-06-27T06:19:58Z					biological_process											owl:Class	
GO:1902905	biolink:NamedThing	positive regulation of supramolecular fiber organization	Any process that activates or increases the frequency, rate or extent of supramolecular fiber organization.	tmpzr1t_l9r_go_relaxed.owl	upregulation of fibril organisation|activation of fibril organization|up regulation of fibril organisation|up regulation of fibril organization|up-regulation of fibril organisation|positive regulation of fibril organisation|activation of fibril organisation|upregulation of fibril organization|up-regulation of fibril organization					HSPA8, human, P11142 in PMID:23921388 inferred from direct assay to negatively regulate fibrillation of alpha-Syn in vitro		rl	2014-04-15T16:46:48Z					biological_process											owl:Class	
GO:1900642	biolink:NamedThing	positive regulation of austinol biosynthetic process	Any process that activates or increases the frequency, rate or extent of austinol biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of austinol anabolism|upregulation of austinol formation|up-regulation of austinol biosynthetic process|upregulation of austinol biosynthetic process|up-regulation of austinol synthesis|activation of austinol biosynthesis|up regulation of austinol biosynthetic process|activation of austinol anabolism|positive regulation of austinol synthesis|positive regulation of austinol anabolism|up-regulation of austinol formation|up regulation of austinol synthesis|upregulation of austinol synthesis|up regulation of austinol biosynthesis|up regulation of austinol anabolism|up-regulation of austinol biosynthesis|upregulation of austinol anabolism|activation of austinol formation|positive regulation of austinol formation|activation of austinol synthesis|positive regulation of austinol biosynthesis|activation of austinol biosynthetic process|upregulation of austinol biosynthesis|up regulation of austinol formation							di	2012-05-22T03:58:07Z					biological_process											owl:Class	
GO:0010894	biolink:NamedThing	negative regulation of steroid biosynthetic process	Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0000833	biolink:NamedThing	inositol heptakisphosphate 4-kinase activity	Catalysis of the reaction: ATP + 5-diphospho-1D-myo-inositol (1,2,3,4,6)pentakisphosphate = 4,5-bisdiphosphoinositol-1D-myoinositol (1,2,3,6)tetrakisphosphate.	tmpzr1t_l9r_go_relaxed.owl	diphosphoinositol-pentakisphosphate 4-kinase activity|IP7 4-kinase activity													molecular_function											owl:Class	
GO:0000829	biolink:NamedThing	inositol heptakisphosphate kinase activity	Catalysis of the reaction: ATP + diphospho-1D-myo-inositol-pentakisphosphate = ADP + bis(diphospho)-1D-myo-inositol-tetrakisphosphate. The isomeric configurations of the diphospho-1D-myo-inositol-pentakisphosphate (PP-IP5) and bis(diphospho)-1D-myo-inositol-tetrakisphosphate (bis-PP-IP4) are unknown.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-1855157|Reactome:R-HSA-1855194|Reactome:R-HSA-1855182									molecular_function											owl:Class	
GO:0030834	biolink:NamedThing	regulation of actin filament depolymerization	Any process that modulates the frequency, rate or extent of the disassembly of actin filaments by the removal of actin monomers from a filament.	tmpzr1t_l9r_go_relaxed.owl	regulation of actin depolymerization													biological_process											owl:Class	
GO:0047854	biolink:NamedThing	diguanidinobutanase activity	Catalysis of the reaction: 1,4-diguanidinobutane + H(2)O = agmatine + urea.	tmpzr1t_l9r_go_relaxed.owl	1,4-diguanidinobutane amidinohydrolase activity				RHEA:13597|MetaCyc:DIGUANIDINOBUTANASE-RXN|KEGG_REACTION:R01418|EC:3.5.3.20									molecular_function											owl:Class	
GO:0048300	biolink:NamedThing	negative regulation of isotype switching to IgD isotypes	Any process that stops, prevents, or reduces the frequency, rate or extent of isotype switching to IgD isotypes.	tmpzr1t_l9r_go_relaxed.owl	downregulation of isotype switching to IgD isotypes|negative regulation of isotype switch recombination to IgD isotypes|negative regulation of class switch recombination to IgD isotypes|down regulation of isotype switching to IgD isotypes|inhibition of isotype switching to IgD isotypes|negative regulation of class switching to IgD isotypes|down-regulation of isotype switching to IgD isotypes													biological_process											owl:Class	
GO:0048299	biolink:NamedThing	regulation of isotype switching to IgD isotypes	Any process that modulates the frequency, rate or extent of isotype switching to IgD isotypes.	tmpzr1t_l9r_go_relaxed.owl	regulation of isotype switch recombination to IgD isotypes|regulation of class switching to IgD isotypes|regulation of class switch recombination to IgD isotypes													biological_process											owl:Class	
GO:0044407	biolink:NamedThing	single-species biofilm formation in or on host organism	A process in which microorganisms of the same species attach to and grow in or on a host species, and produce extracellular polymers that facilitate attachment and matrix formation, resulting in a change in the microorganisms' growth rate and gene transcription. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0044010	biolink:NamedThing	single-species biofilm formation	A process in which planktonically growing microorganisms of the same species grow at a liquid-air interface or on a solid substrate under the flow of a liquid and produce extracellular polymers that facilitate matrix formation, resulting in a change in the organisms' growth rate and gene transcription.	tmpzr1t_l9r_go_relaxed.owl	bundle-forming pili-dependent aggregation|tfp-dependent aggregation|bundle-forming fimbriae-dependent aggregation|bfp-dependent aggregation|auto-aggregation|type IV pili-dependent aggregation	https://github.com/geneontology/go-ontology/issues/18814										GO:0052000		biological_process											owl:Class	
GO:0070862	biolink:NamedThing	negative regulation of protein exit from endoplasmic reticulum	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of proteins from the endoplasmic reticulum.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of protein exit from endoplasmic reticulum|inhibition of protein exit from endoplasmic reticulum|negative regulation of protein export from ER|downregulation of protein exit from endoplasmic reticulum|down regulation of protein exit from endoplasmic reticulum|negative regulation of protein exit from ER|negative regulation of protein export from endoplasmic reticulum							mah	2009-08-17T03:45:56Z					biological_process											owl:Class	
GO:0070861	biolink:NamedThing	regulation of protein exit from endoplasmic reticulum	Any process that modulates the frequency, rate or extent of the directed movement of proteins from the endoplasmic reticulum.	tmpzr1t_l9r_go_relaxed.owl	regulation of protein export from endoplasmic reticulum|regulation of protein export from ER|regulation of protein exit from ER							mah	2009-08-17T03:39:18Z					biological_process											owl:Class	
GO:0097076	biolink:NamedThing	transforming growth factor beta activated kinase 1 complex	A protein complex that possesses protein kinase activity and activates the I-kappa B kinase complex (IKK) and mitogen-activated protein (MAP) kinases in response to TRAF6 signaling. It comprises the catalytic subunit TAK1 complexed to the regulatory subunits, termed TABs (TAK1-binding subunits).	tmpzr1t_l9r_go_relaxed.owl	TAK1 kinase complex							pr	2011-06-15T04:55:32Z					cellular_component											owl:Class	
GO:0036367	biolink:NamedThing	light adaption	The ability of a photoreceptor to adjust to varying levels of light.	tmpzr1t_l9r_go_relaxed.owl						Light adaptation is usually a combination of cell desensitization and response acceleration.		bf	2012-09-26T13:28:14Z					biological_process											owl:Class	
GO:0009642	biolink:NamedThing	response to light intensity	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light intensity stimulus.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1902635	biolink:NamedThing	1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate.	tmpzr1t_l9r_go_relaxed.owl	1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate formation|1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate anabolism|1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthesis|1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate synthesis					Phosphatidylinositol-4,5-bisphosphate, PtdIns(4,5)P(2) common name.		di	2014-01-18T00:34:45Z					biological_process											owl:Class	
GO:1902633	biolink:NamedThing	1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate metabolic process	The chemical reactions and pathways involving 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate.	tmpzr1t_l9r_go_relaxed.owl	1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate metabolism					Phosphatidylinositol-4,5-bisphosphate, PtdIns(4,5)P(2) common name.		di	2014-01-18T00:34:27Z					biological_process											owl:Class	
GO:0047373	biolink:NamedThing	acetoxybutynylbithiophene deacetylase activity	Catalysis of the reaction: 5-(4-acetoxybut-1-ynyl)-2,2'-bithiophene + H(2)O = 5-(4-hydroxy-but-1-ynyl)-2,2'-bithiophene + acetate + H(+).	tmpzr1t_l9r_go_relaxed.owl	5-(4-acetoxybut-1-ynyl)-2,2'-bithiophene O-acetylhydrolase activity|5-(4-acetoxy-1-butynyl)-2,2'-bithiophene:acetate esterase activity|acetoxybutynylbithiophene esterase activity				EC:3.1.1.54|KEGG_REACTION:R04490|RHEA:11548|MetaCyc:3.1.1.54-RXN									molecular_function											owl:Class	
GO:0019213	biolink:NamedThing	deacetylase activity	Catalysis of the hydrolysis of an acetyl group or groups from a substrate molecule.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-5689000									molecular_function											owl:Class	
GO:1900827	biolink:NamedThing	positive regulation of membrane depolarization during cardiac muscle cell action potential	Any process that activates or increases the frequency, rate or extent of membrane depolarization during a cardiac muscle cell action potential.	tmpzr1t_l9r_go_relaxed.owl	up regulation of membrane depolarization during cardiac muscle cell action potential|activation of membrane depolarization during cardiac muscle cell action potential|upregulation of membrane depolarization during cardiac muscle cell action potential|up-regulation of membrane depolarization during cardiac muscle cell action potential							rl	2012-06-06T04:15:48Z					biological_process											owl:Class	
GO:0035395	biolink:NamedThing	negative regulation of chemokine (C-X-C motif) ligand 9 production	Any process that stops, prevents, or reduces the frequency, rate, or extent of production of chemokine (C-X-C motif) ligand 9.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of MIG production|negative regulation of CXCL9 production							bf	2010-03-23T10:06:44Z					biological_process											owl:Class	
GO:0014715	biolink:NamedThing	myoblast fate commitment in trunk	The process taking place in the trunk whereby the developmental fate of a cell becomes restricted such that it will develop into a myoblast. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0042648	biolink:NamedThing	chloroplast chromosome	A circular DNA molecule containing chloroplast encoded genes.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0009508	biolink:NamedThing	plastid chromosome	A circular DNA molecule containing plastid encoded genes.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0015299	biolink:NamedThing	solute:proton antiporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: solute(out) + H+(in) = solute(in) + H+(out).	tmpzr1t_l9r_go_relaxed.owl	L-arabinose/beta-D-thiogalactopyranoside:hydrogen antiporter activity|solute:hydrogen antiporter activity				Reactome:R-HSA-597628|Reactome:R-HSA-5625574|Reactome:R-HSA-434650									molecular_function											owl:Class	
GO:0002551	biolink:NamedThing	mast cell chemotaxis	The movement of a mast cell in response to an external stimulus.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0030595	biolink:NamedThing	leukocyte chemotaxis	The movement of a leukocyte in response to an external stimulus.	tmpzr1t_l9r_go_relaxed.owl	immune cell chemotaxis|leucocyte chemotaxis													biological_process											owl:Class	
GO:0036446	biolink:NamedThing	myofibroblast differentiation	The process in which an undifferentiated cell acquires the features of a myofibroblast cell.	tmpzr1t_l9r_go_relaxed.owl	myofibroblast cell differentiation							bf	2013-10-30T10:06:51Z					biological_process											owl:Class	
GO:0045998	biolink:NamedThing	positive regulation of ecdysteroid biosynthetic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of ecdysteroids.	tmpzr1t_l9r_go_relaxed.owl	stimulation of ecdysteroid biosynthetic process|activation of ecdysteroid biosynthetic process|upregulation of ecdysteroid biosynthetic process|positive regulation of ecdysteroid biosynthesis|positive regulation of ecdysteroid anabolism|positive regulation of ecdysteroid synthesis|up-regulation of ecdysteroid biosynthetic process|up regulation of ecdysteroid biosynthetic process|positive regulation of ecdysteroid formation													biological_process											owl:Class	
GO:0140711	biolink:NamedThing	positive regulation of Frizzled Nuclear Import pathway	Any process that activates or increases the frequency, rate or extent of a Frizzled Nuclear Import pathway.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of FNI|positive regulation of Frizzled Nuclear Import Wnt Pathway	https://github.com/geneontology/go-ontology/issues/21483						pg	2021-09-08T09:17:38Z					biological_process											owl:Class	
GO:2000052	biolink:NamedThing	positive regulation of non-canonical Wnt signaling pathway	Any process that activates or increases the frequency, rate or extent of non-canonical Wnt-activated signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of non-canonical Wnt-activated signaling pathway|positive regulation of non-canonical Wnt receptor signalling pathway|positive regulation of beta-catenin-independent Wnt receptor signaling pathway|positive regulation of non-canonical Wnt receptor signaling pathway							jl	2010-08-20T01:04:25Z					biological_process											owl:Class	
GO:0140614	biolink:NamedThing	1,8-dihydroxynaphthalene-melanin biosynthetic process	The chemical reactions and pathways resulting in the formation of dihydroxy naphthalene (DHN)-melanin.	tmpzr1t_l9r_go_relaxed.owl	DHN-melanin biosynthesis	https://github.com/geneontology/go-ontology/issues/20974						pg	2021-03-04T11:54:05Z					biological_process											owl:Class	
GO:0042438	biolink:NamedThing	melanin biosynthetic process	The chemical reactions and pathways resulting in the formation of melanins, pigments largely of animal origin. High molecular weight polymers of indole quinone, they are irregular polymeric structures and are divided into three groups: allomelanins in the plant kingdom and eumelanins and phaeomelanins in the animal kingdom.	tmpzr1t_l9r_go_relaxed.owl	melanin formation|melanin anabolism|melanin biosynthesis|melanin synthesis													biological_process											owl:Class	
GO:1990008	biolink:NamedThing	neurosecretory vesicle	A large cytoplasmic membrane-bounded vesicle with an electron dense granular core, up to 150-200 nm in diameter, found in neurosecretory cells in the hypothalamus.	tmpzr1t_l9r_go_relaxed.owl					NIF_Subcellular:sao2031592629			pr	2012-12-12T09:56:14Z					cellular_component											owl:Class	
GO:1990005	biolink:NamedThing	granular vesicle	A cytoplasmic membrane-bounded vesicle of varying size, but usually larger than 45 nm, with an electron dense granular core, found in noradrenergic and peptidergic cells.	tmpzr1t_l9r_go_relaxed.owl					NIF_Subcellular:sao478230652			pr	2012-12-11T14:51:48Z					cellular_component											owl:Class	
GO:0060239	biolink:NamedThing	positive regulation of signal transduction involved in conjugation with cellular fusion	Any process that increases the rate, frequency or extent of the series of molecular signals that bring about the relay, amplification or dampening of a signal generated in response to a cue, such as starvation or pheromone exposure, in organisms that undergo conjugation with cellular fusion.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0060238	biolink:NamedThing	regulation of signal transduction involved in conjugation with cellular fusion	Any process that modulates the rate, frequency or extent of pheromone-dependent signal transduction during conjugation with cellular fusion, the series of molecular signals that bring about the relay, amplification or dampening of a signal generated in response to a cue, such as starvation or pheromone exposure, in organisms that undergo conjugation with cellular fusion.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1903294	biolink:NamedThing	regulation of glutamate secretion, neurotransmission	Any process that modulates the frequency, rate or extent of glutamate secretion, neurotransmission.	tmpzr1t_l9r_go_relaxed.owl						An example of this is Rab3gap1 in mouse (Q80UJ7) in PMID:16782817 inferred from mutant phenotype		pad	2014-08-13T13:54:15Z					biological_process											owl:Class	
GO:2000905	biolink:NamedThing	negative regulation of starch metabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of starch metabolic process.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of starch metabolism							tb	2011-07-28T11:33:17Z					biological_process											owl:Class	
GO:0019388	biolink:NamedThing	galactose catabolic process	The chemical reactions and pathways resulting in the breakdown of galactose, the aldohexose galacto-hexose.	tmpzr1t_l9r_go_relaxed.owl	galactose breakdown|galactose degradation|galactose catabolism				MetaCyc:GALDEG-PWY									biological_process											owl:Class	
GO:0072121	biolink:NamedThing	head kidney maturation	A developmental process, independent of morphogenetic (shape) change, that is required for the head kidney to attain its fully functional state. The head kidney is a pronephros that consists of fused bilateral lobes located in the anterior part of the kidney.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-02-22T11:28:08Z					biological_process											owl:Class	
GO:0072120	biolink:NamedThing	pronephros maturation	A developmental process, independent of morphogenetic (shape) change, that is required for the pronephros to attain its fully functional state. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life.	tmpzr1t_l9r_go_relaxed.owl	pronephric kidney maturation							mah	2010-02-22T11:25:48Z					biological_process											owl:Class	
GO:0036005	biolink:NamedThing	response to macrophage colony-stimulating factor	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a macrophage colony-stimulating factor stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to macrophage colony-stimulating factor stimulus|response to M-CSF							bf	2011-09-20T04:22:03Z					biological_process											owl:Class	
GO:2000374	biolink:NamedThing	regulation of oxygen metabolic process	Any process that modulates the frequency, rate or extent of oxygen metabolic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of diatomic oxygen metabolic process|regulation of oxygen metabolism							mah	2011-02-11T02:03:32Z					biological_process											owl:Class	
GO:0010765	biolink:NamedThing	positive regulation of sodium ion transport	Any process that increases the frequency, rate or extent of the directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0016295	biolink:NamedThing	myristoyl-[acyl-carrier-protein] hydrolase activity	Catalysis of the reaction: myristoyl-[acyl-carrier protein] + H2O = [acyl-carrier protein] + myristate.	tmpzr1t_l9r_go_relaxed.owl	tetradecanoyl-ACP hydrolase activity|myristoyl-[acyl-carrier protein] hydrolase activity|myristoyl-ACP hydrolase activity|tetradecanoyl-[acyl-carrier-protein] hydrolase activity				EC:3.1.2.14|KEGG_REACTION:R08159|MetaCyc:RXN-10727|RHEA:30123									molecular_function											owl:Class	
GO:0016297	biolink:NamedThing	acyl-[acyl-carrier-protein] hydrolase activity	Catalysis of the reaction: acyl-[acyl-carrier protein] + H2O = [acyl-carrier protein] + a fatty acid.	tmpzr1t_l9r_go_relaxed.owl	acyl-ACP-hydrolase activity|acyl-ACP hydrolase activity|acyl-[acyl-carrier protein] hydrolase activity|acyl-ACP thioesterase activity|acyl-acyl carrier protein hydrolase activity|S-acyl fatty acid synthase thioesterase activity|acyl-acyl-carrier-protein hydrolase activity				MetaCyc:RXN-7902|Reactome:R-HSA-5655955|EC:3.1.2.14|RHEA:30131							GO:0010281		molecular_function											owl:Class	
GO:0061957	biolink:NamedThing	NVT complex	A protein complex that is capable of contributing to protein localization by the NVT pathway. In fission yeast, the Nvt complex consists of Ape2, Lap2 and Nbr1.	tmpzr1t_l9r_go_relaxed.owl								dph	2017-12-01T17:01:17Z					cellular_component											owl:Class	
GO:2001195	biolink:NamedThing	negative regulation of lysine biosynthetic process via alpha-aminoadipate and saccharopine	Any process that stops, prevents or reduces the frequency, rate or extent of lysine biosynthetic process via alpha-aminoadipate and saccharopine.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of lysine biosynthetic process via aminoadipic acid and saccharopine|negative regulation of lysine biosynthesis via aminoadipic acid and saccharopine							mcc	2011-11-03T07:57:18Z					biological_process											owl:Class	
GO:0120106	biolink:NamedThing	mitotic actomyosin contractile ring, distal actin filament layer	The region of the mitotic actomyosin ring containing actin filaments and cross linkers, myosin motors, and connections to the plasma membrane through the intermediate layer. It is further from the plasma membrane than the intermediate layer which it is adjacent to.	tmpzr1t_l9r_go_relaxed.owl	actomyosin contractile ring, distal actin filament layer							krc	2017-10-11T22:56:44Z					cellular_component											owl:Class	
GO:0042455	biolink:NamedThing	ribonucleoside biosynthetic process	The chemical reactions and pathways resulting in the formation of any ribonucleoside, a nucleoside in which purine or pyrimidine base is linked to a ribose (beta-D-ribofuranose) molecule.	tmpzr1t_l9r_go_relaxed.owl	ribonucleoside formation|ribonucleoside anabolism|ribonucleoside synthesis|ribonucleoside biosynthesis													biological_process											owl:Class	
GO:0009119	biolink:NamedThing	ribonucleoside metabolic process	The chemical reactions and pathways involving any ribonucleoside, a nucleoside in which purine or pyrimidine base is linked to a ribose (beta-D-ribofuranose) molecule.	tmpzr1t_l9r_go_relaxed.owl	ribonucleoside metabolism													biological_process											owl:Class	
GO:0097077	biolink:NamedThing	copper ion sensor activity	Binding to and responding, e.g. by conformational change, to changes in the cellular level of copper(I) (Cu+).	tmpzr1t_l9r_go_relaxed.owl								pr	2011-06-17T09:57:11Z					molecular_function											owl:Class	
GO:0140215	biolink:NamedThing	regulation of D-aspartate import across plasma membrane	Any process that modulates the frequency, rate or extent of the directed import of D-aspartate from the extracellular region across the plasma membrane and into the cytosol.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/15041						pg	2018-04-11T15:33:35Z					biological_process											owl:Class	
GO:1901777	biolink:NamedThing	mitomycin C biosynthetic process	The chemical reactions and pathways resulting in the formation of mitomycin C.	tmpzr1t_l9r_go_relaxed.owl	mitomycin C anabolism|mitomycin C formation|mitomycin C synthesis|mitomycin C biosynthesis							yaf	2013-01-15T12:11:57Z					biological_process											owl:Class	
GO:0017150	biolink:NamedThing	tRNA dihydrouridine synthase activity	Catalysis of the reaction: tRNA-uracil + acceptor = tRNA-dihydrouridine + reduced acceptor.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-6782296|MetaCyc:RXN0-1281|RHEA:23624									molecular_function											owl:Class	
GO:1905139	biolink:NamedThing	apical ectodermal ridge formation	The process that gives rise to the apical ectodermal ridge. This process pertains to the initial formation of a structure from unspecified parts.	tmpzr1t_l9r_go_relaxed.owl	crista ectodermalis apicalis formation|apical epidermal ridge formation|AER formation							dph	2016-04-13T11:46:40Z					biological_process											owl:Class	
GO:0006547	biolink:NamedThing	histidine metabolic process	The chemical reactions and pathways involving histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid.	tmpzr1t_l9r_go_relaxed.owl	histidine metabolism				Wikipedia:Histidine									biological_process											owl:Class	
GO:1901671	biolink:NamedThing	positive regulation of superoxide dismutase activity	Any process that activates or increases the frequency, rate or extent of superoxide dismutase activity.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of cytocuprein|up regulation of superoxide dismutase activity|positive regulation of erythrocuprein|up-regulation of superoxide:superoxide oxidoreductase activity|positive regulation of Fe-SOD|activation of SOD-2|up regulation of Cu-Zn superoxide dismutase activity|up regulation of cuprein|positive regulation of SOD-1|upregulation of SOD|activation of SODS|up-regulation of nickel superoxide oxidoreductase|up regulation of superoxide dismutase I|positive regulation of SODF|up regulation of SOD-4|upregulation of iron superoxide oxidoreductase|positive regulation of hepatocuprein|upregulation of superoxide dismutase activity|up regulation of erythrocuprein|positive regulation of SODS|up regulation of Mn-SOD|up-regulation of manganese superoxide dismutase activity|up-regulation of superoxide dismutase II|upregulation of SOD-1|positive regulation of SOD-2|up-regulation of hepatocuprein|up regulation of hepatocuprein|upregulation of SODF|upregulation of hepatocuprein|positive regulation of Mn-SOD|positive regulation of iron superoxide oxidoreductase|activation of cuprein|up-regulation of SOD-2|upregulation of SODS|activation of SODF|activation of superoxide dismutase II|up regulation of manganese superoxide dismutase activity|upregulation of nickel superoxide dismutase activity|up regulation of superoxide dismutase II|up-regulation of SOD-4|positive regulation of nickel superoxide oxidoreductase|up regulation of nickel superoxide dismutase activity|activation of SOD-3|up regulation of Mn, Fe superoxide dismutase|up-regulation of cytocuprein|activation of superoxide dismutase activity|positive regulation of Cu,Zn-SOD|up-regulation of superoxide dismutase I|up regulation of zinc superoxide oxidoreductase|activation of erythrocuprein|positive regulation of cuprein|upregulation of superoxide:superoxide oxidoreductase activity|upregulation of Cu,Zn-SOD|activation of SOD|upregulation of zinc superoxide oxidoreductase|up-regulation of iron superoxide dismutase activity|up-regulation of zinc superoxide oxidoreductase|activation of superoxide:superoxide oxidoreductase activity|upregulation of Cu-Zn superoxide dismutase activity|up-regulation of hemocuprein|positive regulation of superoxide dismutase I|activation of SOD-1|activation of superoxide dismutase I|activation of hepatocuprein|up regulation of SOD-1|up regulation of manganese superoxide oxidoreductase|positive regulation of Cu-Zn superoxide dismutase activity|positive regulation of Mn, Fe superoxide dismutase|activation of nickel superoxide oxidoreductase|up-regulation of erythrocuprein|up regulation of hemocuprein|upregulation of ferrisuperoxide dismutase activity|upregulation of cytocuprein|up-regulation of SOD-3|up-regulation of Cu-Zn superoxide dismutase activity|up-regulation of nickel superoxide dismutase activity|up regulation of SODF|upregulation of Fe-SOD|upregulation of nickel superoxide oxidoreductase|upregulation of Mn, Fe superoxide dismutase|upregulation of SOD-3|up-regulation of SOD-1|positive regulation of SOD|up-regulation of Fe-SOD|up regulation of superoxide:superoxide oxidoreductase activity|positive regulation of iron superoxide dismutase activity|activation of Cu,Zn-SOD|up regulation of cytocuprein|upregulation of copper, zinc superoxide dismutase activity|activation of manganese superoxide dismutase activity|up regulation of Cu,Zn-SOD|activation of zinc superoxide oxidoreductase|up-regulation of manganese superoxide oxidoreductase|up regulation of SOD-2|upregulation of cuprein|upregulation of erythrocuprein|positive regulation of manganese superoxide dismutase activity|up regulation of SOD-3|up-regulation of copper, zinc superoxide dismutase activity|up-regulation of SODF|up-regulation of SOD|positive regulation of superoxide:superoxide oxidoreductase activity|activation of hemocuprein|activation of iron superoxide oxidoreductase|upregulation of superoxide dismutase II|positive regulation of hemocuprein|positive regulation of nickel superoxide dismutase activity|up regulation of SODS|up regulation of ferrisuperoxide dismutase activity|upregulation of Mn-SOD|up-regulation of iron superoxide oxidoreductase|up regulation of copper, zinc superoxide dismutase activity|upregulation of manganese superoxide dismutase activity|up-regulation of Mn, Fe superoxide dismutase|upregulation of iron superoxide dismutase activity|positive regulation of manganese superoxide oxidoreductase|activation of Fe-SOD|up-regulation of superoxide dismutase activity|activation of ferrisuperoxide dismutase activity|up regulation of iron superoxide dismutase activity|activation of manganese superoxide oxidoreductase|activation of SOD-4|up-regulation of SODS|activation of Cu-Zn superoxide dismutase activity|positive regulation of SOD-4|positive regulation of copper, zinc superoxide dismutase activity|activation of nickel superoxide dismutase activity|up-regulation of cuprein|positive regulation of zinc superoxide oxidoreductase|up regulation of SOD|upregulation of SOD-4|up-regulation of ferrisuperoxide dismutase activity|activation of Mn, Fe superoxide dismutase|upregulation of SOD-2|activation of Mn-SOD|up-regulation of Mn-SOD|positive regulation of superoxide dismutase II|up regulation of iron superoxide oxidoreductase|activation of iron superoxide dismutase activity|up regulation of nickel superoxide oxidoreductase|activation of copper, zinc superoxide dismutase activity|activation of cytocuprein|positive regulation of SOD-3|upregulation of manganese superoxide oxidoreductase|upregulation of hemocuprein|up-regulation of Cu,Zn-SOD|positive regulation of ferrisuperoxide dismutase activity|upregulation of superoxide dismutase I|up regulation of Fe-SOD							tb	2012-11-21T21:36:11Z					biological_process											owl:Class	
GO:0050470	biolink:NamedThing	trimethylamine dehydrogenase activity	Catalysis of the reaction: trimethylamine + H2O + electron-transferring flavoprotein = dimethylamine + formaldehyde + reduced electron-transferring flavoprotein.	tmpzr1t_l9r_go_relaxed.owl	trimethylamine:electron-transferring flavoprotein oxidoreductase (demethylating)|TMADh activity				UM-BBD_enzymeID:e0854|EC:1.5.8.2|MetaCyc:1.5.8.2-RXN|RHEA:11864									molecular_function											owl:Class	
GO:1903141	biolink:NamedThing	negative regulation of establishment of endothelial barrier	Any process that stops, prevents or reduces the frequency, rate or extent of establishment of endothelial barrier.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of establishment of endothelial barrier|inhibition of establishment of endothelial barrier|down regulation of establishment of endothelial barrier|downregulation of establishment of endothelial barrier							als	2014-07-01T12:12:40Z					biological_process											owl:Class	
GO:0045500	biolink:NamedThing	sevenless signaling pathway	A series of molecular signals initiated by the binding of an extracellular ligand to sevenless (sev; a receptor tyrosine kinase) on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.	tmpzr1t_l9r_go_relaxed.owl	sev receptor signaling pathway|sev signaling pathway|sevenless signalling pathway													biological_process											owl:Class	
GO:0050003	biolink:NamedThing	deoxycytidylate C-methyltransferase activity	Catalysis of the reaction: 5,10-methylenetetrahydrofolate + dCMP = 2'-deoxy-5-methyl-5'-cytidylate + 7,8-dihydrofolate.	tmpzr1t_l9r_go_relaxed.owl	deoxycytidylate methyltransferase activity|dCMP methyltransferase activity|5,10-methylenetetrahydrofolate:dCMP C-methyltransferase activity				EC:2.1.1.54|RHEA:11568|MetaCyc:DEOXYCYTIDYLATE-C-METHYLTRANSFERASE-RXN|KEGG_REACTION:R01670									molecular_function											owl:Class	
GO:0106210	biolink:NamedThing	culmorin biosynthetic process	The chemical reactions and pathways resulting in the formation of culmorin, a sesquiterpenoid fungal metabolite and mycotoxin produced by some ascomycete species such as Fusarium culmorum, F. graminearum, F. venenatum and Leptosphaeria oraemaris.	tmpzr1t_l9r_go_relaxed.owl	culmorin anabolism|culmorin biosynthesis|culmorin formation|culmorin synthesis							hjd	2019-05-13T17:30:41Z					biological_process											owl:Class	
GO:0047201	biolink:NamedThing	beta-glucogallin O-galloyltransferase activity	Catalysis of the reaction: 2 1-O-galloyl-beta-D-glucose = 1,6-bis-O-galloyl-beta-D-glucose + D-glucose.	tmpzr1t_l9r_go_relaxed.owl	1-O-galloyl-beta-D-glucose:1-O-galloyl-beta-D-glucose O-galloyltransferase activity				RHEA:11416|MetaCyc:2.3.1.90-RXN|EC:2.3.1.90|KEGG_REACTION:R00049									molecular_function											owl:Class	
GO:2001137	biolink:NamedThing	positive regulation of endocytic recycling	Any process that activates or increases the frequency, rate or extent of endocytic recycling.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of retrograde transport of endocytic vesicles							kmv	2011-10-14T03:34:49Z					biological_process											owl:Class	
GO:2000219	biolink:NamedThing	positive regulation of invasive growth in response to glucose limitation	Any process that activates or increases the frequency, rate or extent of invasive growth in response to glucose limitation.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of colony morphology							mah	2010-11-03T04:36:02Z					biological_process											owl:Class	
GO:0050803	biolink:NamedThing	regulation of synapse structure or activity	Any process that modulates the physical form or the activity of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell).	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0015896	biolink:NamedThing	nalidixic acid transport	The directed movement of nalidixic acid into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Nalidixic acid is a synthetic antibiotic that interferes with DNA gyrase and inhibits prokaryotic replication.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0061738	biolink:NamedThing	late endosomal microautophagy	The autophagy process by which cytosolic proteins targeted for degradation are tagged with a chaperone and are directly transferred into and degraded in a late endosomal compartment.	tmpzr1t_l9r_go_relaxed.owl								dph	2015-09-24T14:40:02Z					biological_process											owl:Class	
GO:0047833	biolink:NamedThing	D-sorbitol dehydrogenase (acceptor) activity	Catalysis of the reaction: D-sorbitol + acceptor = L-sorbose + reduced acceptor.	tmpzr1t_l9r_go_relaxed.owl	D-sorbitol dehydrogenase activity|D-sorbitol:(acceptor) 1-oxidoreductase activity|D-sorbitol:acceptor 1-oxidoreductase activity				RHEA:21320|MetaCyc:D-SORBITOL-DEHYDROGENASE-RXN|EC:1.1.99.21									molecular_function											owl:Class	
GO:0062090	biolink:NamedThing	positive regulation of taurine biosynthetic process	Any process that activates or increases the frequency, rate or extent of taurine biosynthesis.	tmpzr1t_l9r_go_relaxed.owl								dph	2018-11-07T14:10:58Z					biological_process											owl:Class	
GO:0048671	biolink:NamedThing	negative regulation of collateral sprouting	Any process that stops, prevents, or reduces the frequency, rate or extent of collateral sprouting.	tmpzr1t_l9r_go_relaxed.owl	downregulation of collateral sprouting|inhibition of collateral sprouting|down regulation of collateral sprouting|down-regulation of collateral sprouting													biological_process											owl:Class	
GO:0030308	biolink:NamedThing	negative regulation of cell growth	Any process that stops, prevents, or reduces the frequency, rate, extent or direction of cell growth.	tmpzr1t_l9r_go_relaxed.owl	downregulation of cell growth|down-regulation of cell growth|inhibition of cell growth|down regulation of cell growth													biological_process											owl:Class	
GO:0098713	biolink:NamedThing	leucine import across plasma membrane	The directed movement of leucine from outside of a cell, across the plasma membrane and into the cytosol.	tmpzr1t_l9r_go_relaxed.owl	L-leucine import into cell|leucine import into cell							mah	2013-06-12T12:27:47Z			GO:1990122		biological_process											owl:Class	
GO:0089718	biolink:NamedThing	amino acid import across plasma membrane	The directed movement of an amino acid from outside of a cell, across the plasma membrane and into the cytosol.	tmpzr1t_l9r_go_relaxed.owl	amino acid transmembrane import|amino acid import into cell|L-amino acid import|L-amino acid uptake							jl	2012-11-14T14:21:41Z			GO:0043092|GO:1902837|GO:0044745		biological_process											owl:Class	
GO:0070171	biolink:NamedThing	negative regulation of tooth mineralization	Any process that stops, prevents, or reduces the frequency, rate or extent of tooth mineralization, the deposition of calcium salts in tooth structures.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0070168	biolink:NamedThing	negative regulation of biomineral tissue development	Any process that stops, prevents, or reduces the frequency, rate or extent of biomineral tissue development, the formation of hard tissues that consist mainly of inorganic compounds.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0008070	biolink:NamedThing	maternal determination of dorsal/ventral axis, ovarian follicular epithelium, germ-line encoded	Polarization of the ovarian follicle cells along the dorsal-ventral axis by a gene product encoded by cells of the germ line.	tmpzr1t_l9r_go_relaxed.owl	maternal determination of dorsal-ventral axis, ovarian follicular epithelium, germ-line encoded|maternal determination of dorsoventral axis, ovarian follicular epithelium, germ-line encoded													biological_process											owl:Class	
GO:1905933	biolink:NamedThing	regulation of cell fate determination	Any process that modulates the frequency, rate or extent of cell fate determination.	tmpzr1t_l9r_go_relaxed.owl								bhm	2017-02-09T11:25:21Z					biological_process											owl:Class	
GO:0110023	biolink:NamedThing	negative regulation of cardiac muscle myoblast proliferation	Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle myoblast proliferation.	tmpzr1t_l9r_go_relaxed.owl								kmv	2017-06-29T15:18:30Z					biological_process											owl:Class	
GO:0110022	biolink:NamedThing	regulation of cardiac muscle myoblast proliferation	Any process that modulates the frequency, rate or extent of cardiac muscle myoblast proliferation.	tmpzr1t_l9r_go_relaxed.owl								kmv	2017-06-29T15:11:47Z					biological_process											owl:Class	
GO:0010375	biolink:NamedThing	stomatal complex patterning	The regionalization process of establishing the non-random spatial arrangement of stomatal complex on the surface of a leaf. The stomatal complex is the stomatal guard cells and their associated epidermal cells.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0019741	biolink:NamedThing	pentacyclic triterpenoid catabolic process	The chemical reactions and pathways resulting in the breakdown of pentacyclic triterpenoid compounds, terpenoids with six isoprene units and 5 carbon rings.	tmpzr1t_l9r_go_relaxed.owl	pentacyclic triterpenoid degradation|pentacyclic triterpenoid breakdown|pentacyclic triterpenoid catabolism													biological_process											owl:Class	
GO:0051308	biolink:NamedThing	male meiosis chromosome separation	The process in which paired chromosomes are physically detached from each other during male meiosis.	tmpzr1t_l9r_go_relaxed.owl	male meiosis chromosome resolution|chromosome separation during male meiosis													biological_process											owl:Class	
GO:0062081	biolink:NamedThing	activating MHC class Ib receptor activity	Combining with a MHC class Ib protein complex to mediate signaling that activates a lymphocyte.	tmpzr1t_l9r_go_relaxed.owl								dph	2018-10-15T15:05:07Z					molecular_function											owl:Class	
GO:0032394	biolink:NamedThing	MHC class Ib receptor activity	Combining with an MHC class Ib protein complex and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. Class Ib here refers to non-classical class I molecules, such as those of the CD1 or HLA-E gene families.	tmpzr1t_l9r_go_relaxed.owl	T cell receptor activity|alpha-beta T cell receptor activity|gamma-delta T cell receptor activity					Note that this term is intended for annotation of gene products that act as receptors for MHC class Ib protein complexes, not for components of the MHC class Ib protein complexes themselves.								molecular_function											owl:Class	
GO:0103101	biolink:NamedThing	UDP-glucose:7-methylthioheptylhydroximate S-glucosyltransferase activity	Catalysis of the reaction: UDP-alpha-D-glucose + 7-methylthioheptylhydroximate <=> H+ + 6-methylthiohexyldesulfoglucosinolate + UDP.	tmpzr1t_l9r_go_relaxed.owl					EC:2.4.1.195|MetaCyc:RXNQT-4326									molecular_function											owl:Class	
GO:0086075	biolink:NamedThing	gap junction channel activity involved in cardiac conduction electrical coupling	A wide pore channel activity that enables a direct cytoplasmic connection from one cardiomyocyte to an adjacent cardiomyocyte. The gap junction passes electrical signals between the cells contributing to cardiac conduction.	tmpzr1t_l9r_go_relaxed.owl								dph	2011-11-22T10:08:29Z					molecular_function											owl:Class	
GO:0005243	biolink:NamedThing	gap junction channel activity	A wide pore channel activity that enables a direct cytoplasmic connection from one cell to an adjacent cell. The gap junction can pass large solutes as well as electrical signals between cells. Gap junctions consist of two gap junction hemi-channels, or connexons, one contributed by each membrane through which the gap junction passes.	tmpzr1t_l9r_go_relaxed.owl	intercellular channel|connexin|innexin channel activity|innexin				Reactome:R-HSA-375340|Reactome:R-HSA-375342|Reactome:R-HSA-375330|Reactome:R-HSA-375339|Reactome:R-HSA-190681							GO:0015286|GO:0015285		molecular_function											owl:Class	
GO:0043496	biolink:NamedThing	regulation of protein homodimerization activity	Any process that modulates the frequency, rate or extent of protein homodimerization, interacting selectively with an identical protein to form a homodimer.	tmpzr1t_l9r_go_relaxed.owl						Note that protein homodimerization is a molecular function: 'protein homodimerization activity ; GO:0042803'.								biological_process											owl:Class	
GO:2000231	biolink:NamedThing	positive regulation of pancreatic stellate cell proliferation	Any process that activates or increases the frequency, rate or extent of pancreatic stellate cell proliferation.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-11-09T03:45:23Z					biological_process											owl:Class	
GO:0048146	biolink:NamedThing	positive regulation of fibroblast proliferation	Any process that activates or increases the frequency, rate or extent of multiplication or reproduction of fibroblast cells.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of fibroblast proliferation|up regulation of fibroblast proliferation|stimulation of fibroblast proliferation|upregulation of fibroblast proliferation|activation of fibroblast proliferation													biological_process											owl:Class	
GO:1901919	biolink:NamedThing	positive regulation of exoribonuclease activity	Any process that activates or increases the frequency, rate or extent of exoribonuclease activity.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of exoribonuclease activity|activation of exoribonuclease activity|upregulation of exoribonuclease activity|up regulation of exoribonuclease activity							rb	2013-02-15T00:58:07Z					biological_process											owl:Class	
GO:1901917	biolink:NamedThing	regulation of exoribonuclease activity	Any process that modulates the frequency, rate or extent of exoribonuclease activity.	tmpzr1t_l9r_go_relaxed.owl								rb	2013-02-15T00:57:56Z					biological_process											owl:Class	
GO:0004967	biolink:NamedThing	glucagon receptor activity	Combining with glucagon and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0032778	biolink:NamedThing	P-type cobalt transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + cobalt(out) = ADP + phosphate + cobalt(in).	tmpzr1t_l9r_go_relaxed.owl	cobalt transporting ATPase activity|ATP-dependent cobalt transmembrane transporter activity|cobalt porter activity|ATPase-coupled cobalt transmembrane transporter activity|cobalt-transporting ATPase activity				RHEA:32779							GO:0015632		molecular_function											owl:Class	
GO:0015087	biolink:NamedThing	cobalt ion transmembrane transporter activity	Enables the transfer of cobalt (Co) ions from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	zinc, cadmium, cobalt, nickel, lead-efflux ATPase activity|cobalt, zinc uptake permease activity				RHEA:28578									molecular_function											owl:Class	
GO:0009114	biolink:NamedThing	hypoxanthine catabolic process	The chemical reactions and pathways resulting in the breakdown of hypoxanthine, 6-hydroxy purine, an intermediate in the degradation of adenylate. Its ribonucleoside is known as inosine and its ribonucleotide as inosinate.	tmpzr1t_l9r_go_relaxed.owl	hypoxanthine catabolism|hypoxanthine breakdown|hypoxanthine degradation|hypoxanthine oxidation											GO:0006150		biological_process											owl:Class	
GO:0006145	biolink:NamedThing	purine nucleobase catabolic process	The chemical reactions and pathways resulting in the breakdown of purine nucleobases, one of the two classes of nitrogen-containing ring compounds found in DNA and RNA, which include adenine and guanine.	tmpzr1t_l9r_go_relaxed.owl	purine base breakdown|purine base catabolism|purine base catabolic process|purine base degradation													biological_process											owl:Class	
GO:0021848	biolink:NamedThing	neuroblast division in subpallium	The division of neuroblasts in the subpallium area of the forebrain. The interneuron precursors that these cells give rise to include GABAergic interneurons and will migrate tangentially.	tmpzr1t_l9r_go_relaxed.owl	neuroblast division in the ventral telencephalon													biological_process											owl:Class	
GO:0055057	biolink:NamedThing	neuroblast division	The process resulting in the physical partitioning and separation of a neuroblast into daughter cells. A neuroblast is any cell that will divide and give rise to a neuron.	tmpzr1t_l9r_go_relaxed.owl	neuroblast cell division													biological_process											owl:Class	
GO:0002596	biolink:NamedThing	negative regulation of antigen processing and presentation of peptide antigen via MHC class Ib	Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class Ib.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of peptide antigen processing and presentation via MHC class Ib|down regulation of antigen processing and presentation of peptide antigen via MHC class Ib|downregulation of antigen processing and presentation of peptide antigen via MHC class Ib|down-regulation of antigen processing and presentation of peptide antigen via MHC class Ib|inhibition of antigen processing and presentation of peptide antigen via MHC class Ib													biological_process											owl:Class	
GO:0002595	biolink:NamedThing	regulation of antigen processing and presentation of peptide antigen via MHC class Ib	Any process that modulates the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class Ib.	tmpzr1t_l9r_go_relaxed.owl	regulation of peptide antigen processing and presentation via MHC class Ib													biological_process											owl:Class	
GO:1903741	biolink:NamedThing	negative regulation of phosphatidate phosphatase activity	Any process that stops, prevents or reduces the frequency, rate or extent of phosphatidate phosphatase activity.	tmpzr1t_l9r_go_relaxed.owl	inhibition of phosphatidic acid phosphatase activity|down-regulation of phosphatidic acid phosphatase activity|downregulation of phosphatic acid phosphatase activity|negative regulation of phosphatidate phosphohydrolase activity|negative regulation of acid phosphatidyl phosphatase activity|down-regulation of phosphatidate phosphatase activity|down regulation of phosphatidate phosphohydrolase activity|downregulation of phosphatidate phosphohydrolase activity|down regulation of phosphatidic acid phosphatase activity|down regulation of 3-sn-phosphatidate phosphohydrolase activity|down regulation of acid phosphatidyl phosphatase activity|inhibition of acid phosphatidyl phosphatase activity|inhibition of phosphatic acid phosphatase activity|downregulation of phosphatic acid phosphohydrolase activity|down-regulation of acid phosphatidyl phosphatase activity|downregulation of acid phosphatidyl phosphatase activity|inhibition of 3-sn-phosphatidate phosphohydrolase activity|inhibition of phosphatic acid phosphohydrolase activity|negative regulation of 3-sn-phosphatidate phosphohydrolase activity|negative regulation of phosphatic acid phosphohydrolase activity|down-regulation of phosphatidate phosphohydrolase activity|downregulation of phosphatidic acid phosphatase activity|downregulation of phosphatidate phosphatase activity|down regulation of phosphatic acid phosphohydrolase activity|inhibition of phosphatidate phosphatase activity|down-regulation of phosphatic acid phosphatase activity|down regulation of phosphatic acid phosphatase activity|inhibition of phosphatidate phosphohydrolase activity|down regulation of phosphatidate phosphatase activity|downregulation of 3-sn-phosphatidate phosphohydrolase activity|negative regulation of phosphatidic acid phosphatase activity|negative regulation of phosphatic acid phosphatase activity|down-regulation of phosphatic acid phosphohydrolase activity|down-regulation of 3-sn-phosphatidate phosphohydrolase activity							tb	2014-12-11T23:37:54Z					biological_process											owl:Class	
GO:1900838	biolink:NamedThing	negative regulation of fumigaclavine C biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of fumigaclavine C biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	inhibition of fumigaclavine C biosynthetic process							di	2012-06-07T09:36:45Z					biological_process											owl:Class	
GO:1900823	biolink:NamedThing	negative regulation of ergot alkaloid biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of ergot alkaloid biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	inhibition of ergot alkaloid anabolism|inhibition of ergot alkaloid formation|inhibition of ergot alkaloid synthesis|down regulation of ergot alkaloid biosynthesis|downregulation of ergot alkaloid biosynthesis|down-regulation of ergot alkaloid anabolism|downregulation of ergot alkaloid biosynthetic process|downregulation of ergot alkaloid formation|down-regulation of ergot alkaloid biosynthesis|down regulation of ergot alkaloid anabolism|negative regulation of ergot alkaloid biosynthesis|down-regulation of ergot alkaloid formation|down regulation of ergot alkaloid biosynthetic process|down-regulation of ergot alkaloid biosynthetic process|inhibition of ergot alkaloid biosynthesis|negative regulation of ergot alkaloid formation|negative regulation of ergot alkaloid synthesis|downregulation of ergot alkaloid synthesis|negative regulation of ergot alkaloid anabolism|down regulation of ergot alkaloid synthesis|down regulation of ergot alkaloid formation|downregulation of ergot alkaloid anabolism|inhibition of ergot alkaloid biosynthetic process|down-regulation of ergot alkaloid synthesis							di	2012-06-04T11:12:54Z					biological_process											owl:Class	
GO:0034191	biolink:NamedThing	apolipoprotein A-I receptor binding	Binding to an apolipoprotein A-I receptor.	tmpzr1t_l9r_go_relaxed.owl						Note that this term is to be used only to annotate gene products that bind to lipid-free APOA1. For receptors that bind lipid-associated apolipoproteins (plasma lipoprotein particles), consider annotating to 'lipoprotein receptor activity ; GO:0030228' or its child terms.								molecular_function											owl:Class	
GO:0034190	biolink:NamedThing	apolipoprotein receptor binding	Binding to an apolipoprotein receptor.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0000393	biolink:NamedThing	spliceosomal conformational changes to generate catalytic conformation	Structural rearrangements of the spliceosome complex, containing RNA to be spliced, to generate a catalytic conformation.	tmpzr1t_l9r_go_relaxed.owl	3'-splice site cleavage, exon ligation													biological_process											owl:Class	
GO:0034865	biolink:NamedThing	2,4,4-trimethylpentanoate-CoA ligase activity	Catalysis of the reaction: 2,4,4-trimethylpentanoate + CoASH = 2,4,4-trimethylpentanoyl-CoA + OH-.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r1271									molecular_function											owl:Class	
GO:0033032	biolink:NamedThing	regulation of myeloid cell apoptotic process	Any process that modulates the frequency, rate, or extent of myeloid cell apoptotic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of myeloid cell apoptosis													biological_process											owl:Class	
GO:0050276	biolink:NamedThing	scyllo-inosamine 4-kinase activity	Catalysis of the reaction: 1-amino-1-deoxy-scyllo-inositol + ATP = 1-amino-1-deoxy-scyllo-inositol 4-phosphate + ADP + 2 H(+).	tmpzr1t_l9r_go_relaxed.owl	ATP:inosamine phosphotransferase activity|ATP:1-amino-1-deoxy-scyllo-inositol 4-phosphotransferase activity|scyllo-inosamine kinase (phosphorylating)|scyllo-inosamine kinase activity				KEGG_REACTION:R03384|EC:2.7.1.65|RHEA:18605|MetaCyc:SCYLLO-INOSAMINE-KINASE-RXN									molecular_function											owl:Class	
GO:0099118	biolink:NamedThing	microtubule-based protein transport	A microtubule-based process that results in the transport of proteins.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0044255	biolink:NamedThing	cellular lipid metabolic process	The chemical reactions and pathways involving lipids, as carried out by individual cells.	tmpzr1t_l9r_go_relaxed.owl	cellular lipid metabolism													biological_process											owl:Class	
GO:0046002	biolink:NamedThing	positive regulation of preblastoderm mitotic cell cycle	Any process that activates or increases the rate or extent of progression through the preblastoderm mitotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl	upregulation of progression through preblastoderm mitotic cell cycle|positive regulation of preblastoderm mitotic cell cycle progression|activation of progression through preblastoderm mitotic cell cycle|up regulation of progression through preblastoderm mitotic cell cycle|up-regulation of progression through preblastoderm mitotic cell cycle|positive regulation of progression through preblastoderm mitotic cell cycle|stimulation of progression through preblastoderm mitotic cell cycle													biological_process											owl:Class	
GO:0007347	biolink:NamedThing	regulation of preblastoderm mitotic cell cycle	A cell cycle process that modulates the rate or extent of the progression through the preblastoderm mitotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl	preblastoderm mitotic cell cycle regulation|preblastoderm mitotic cell cycle modulation|modulation of preblastoderm mitotic cell cycle progression|regulation of preblastoderm mitotic cell cycle progression|regulation of progression through preblastoderm mitotic cell cycle|preblastoderm mitotic cell cycle regulator													biological_process											owl:Class	
GO:0062188	biolink:NamedThing	anandamide 11,12 epoxidase activity	Catalysis of the reaction: N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine + O2 + reduced [NADPH--hemoprotein reductase] = H(+) + H2O + N-(11,12-epoxy-5Z,8Z,14Z-eicosatrienoyl)-ethanolamine + oxidized [NADPH--hemoprotein reductase].	tmpzr1t_l9r_go_relaxed.owl					RHEA:53144			dph	2019-11-26T18:53:52Z					molecular_function											owl:Class	
GO:0062186	biolink:NamedThing	anandamide epoxidase activity	Catalysis of the epoxidation of double bonds of the arachidonoyl moiety of anandamide.	tmpzr1t_l9r_go_relaxed.owl	arachidonoylethanolamide epoxidase activity							dph	2019-11-26T18:49:50Z					molecular_function											owl:Class	
GO:1902948	biolink:NamedThing	negative regulation of tau-protein kinase activity	Any process that stops, prevents or reduces the frequency, rate or extent of tau-protein kinase activity.	tmpzr1t_l9r_go_relaxed.owl	inhibition of tau-protein kinase I activity|inhibition of tau protein kinase activity|down-regulation of TPK I|down regulation of TPK I|negative regulation of TPK|down-regulation of tau kinase activity|inhibition of TPK|negative regulation of TTK|downregulation of tau-protein kinase II activity|down-regulation of tau-protein kinase activity|inhibition of TPK I|negative regulation of TPK I|inhibition of tau-protein kinase activity|inhibition of tau-protein kinase II activity|negative regulation of CDK5/p23|downregulation of tau protein kinase activity|downregulation of tau-protein kinase I activity|down regulation of tau-protein kinase I activity|inhibition of TPK II|negative regulation of protein tau kinase activity|negative regulation of cdk5/p20|negative regulation of tau-protein kinase I activity|downregulation of [Tau protein] kinase activity|negative regulation of STK31|negative regulation of GSK|negative regulation of TPK II|inhibition of brain protein kinase PK40erk activity|down-regulation of tau-protein kinase II activity|down-regulation of cdk5/p20|inhibition of cdk5/p20|inhibition of tau kinase activity|negative regulation of tau kinase activity|down regulation of tau-tubulin kinase activity|down regulation of tau-protein kinase II activity|down regulation of brain protein kinase PK40erk activity|inhibition of STK31|negative regulation of tau-protein kinase II activity|inhibition of protein tau kinase activity|downregulation of CDK5/p23|inhibition of [Tau protein] kinase activity|down regulation of tau-protein kinase activity|downregulation of tau kinase activity|down-regulation of [Tau protein] kinase activity|negative regulation of tau-tubulin kinase activity|downregulation of cdk5/p20|down regulation of TTK|negative regulation of [Tau protein] kinase activity|inhibition of CDK5/p23|downregulation of TPK|down-regulation of TPK|down-regulation of TTK|downregulation of tau-tubulin kinase activity|down-regulation of GSK|down-regulation of brain protein kinase PK40erk activity|down regulation of tau protein kinase activity|down regulation of CDK5/p23|down regulation of glycogen synthase kinase-3beta activity|negative regulation of tau protein kinase activity|inhibition of glycogen synthase kinase-3beta activity|down regulation of [Tau protein] kinase activity|downregulation of brain protein kinase PK40erk activity|inhibition of TTK|downregulation of TPK II|down-regulation of tau-tubulin kinase activity|down-regulation of glycogen synthase kinase-3beta activity|down regulation of TPK II|downregulation of protein tau kinase activity|down-regulation of tau protein kinase activity|down-regulation of protein tau kinase activity|downregulation of STK31|down-regulation of STK31|down regulation of cdk5/p20|downregulation of GSK|down regulation of TPK|downregulation of tau-protein kinase activity|downregulation of TTK|down regulation of GSK|down-regulation of tau-protein kinase I activity|inhibition of GSK|down-regulation of TPK II|negative regulation of glycogen synthase kinase-3beta activity|downregulation of glycogen synthase kinase-3beta activity|down-regulation of CDK5/p23|down regulation of protein tau kinase activity|inhibition of tau-tubulin kinase activity|down regulation of tau kinase activity|negative regulation of brain protein kinase PK40erk activity|downregulation of TPK I|down regulation of STK31							sjp	2014-05-02T08:43:32Z					biological_process											owl:Class	
GO:0006469	biolink:NamedThing	negative regulation of protein kinase activity	Any process that stops, prevents, or reduces the frequency, rate or extent of protein kinase activity.	tmpzr1t_l9r_go_relaxed.owl	downregulation of protein kinase activity|down regulation of protein kinase activity|down-regulation of protein kinase activity|inhibition of protein kinase activity													biological_process											owl:Class	
GO:0070150	biolink:NamedThing	mitochondrial glycyl-tRNA aminoacylation	The process of coupling glycine to glycyl-tRNA in a mitochondrion, catalyzed by glycyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0047298	biolink:NamedThing	(S)-3-amino-2-methylpropionate transaminase activity	Catalysis of the reaction: (S)-3-amino-2-methylpropanoate + 2-oxoglutarate = 2-methyl-3-oxopropanoate + L-glutamate.	tmpzr1t_l9r_go_relaxed.owl	(S)-3-amino-2-methylpropanoate:2-oxoglutarate aminotransferase activity|beta-aminoisobutyrate-alpha-ketoglutarate transaminase activity|(S)-3-amino-2-methylpropionate aminotransferase activity|L-3-aminoisobutyric aminotransferase activity|L-3-aminoisobutyrate transaminase activity|L-3-aminoisobutyrate aminotransferase activity|L-AIBAT activity|beta-aminobutyric transaminase activity				MetaCyc:2.6.1.22-RXN|EC:2.6.1.22|KEGG_REACTION:R04188|RHEA:13993									molecular_function											owl:Class	
GO:0015446	biolink:NamedThing	ATPase-coupled arsenite transmembrane transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + arsenite(in) = ADP + phosphate + arsenite(out).	tmpzr1t_l9r_go_relaxed.owl	arsenical resistance ATPase activity|arsenite ABC transporter|arsenite-transmembrane transporting ATPase activity|arsenite-translocating ATPase activity|arsenical resistance efflux pump|arsenical pump-driving ATPase activity|arsenite-transporting ATPase activity|arsenite transporting ATPase activity				TC:3.A.4.1.1|EC:7.3.2.7|MetaCyc:3.6.3.16-RXN|RHEA:11348	EC:7.3.2.7 states that this bacterial transporter does not belong to the ABC superfamily, and instead is a member of its own family, referred to as the Ars family. Like ABC transporters, it contains two nucleotide binding sites (PMID:10970874).								molecular_function											owl:Class	
GO:0022853	biolink:NamedThing	active ion transmembrane transporter activity	Enables the transfer of an ion from one side of a membrane to the other up the solute's concentration gradient. This is carried out by binding the solute and undergoing a series of conformational changes. Transport works equally well in either direction.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0072504	biolink:NamedThing	cellular trivalent inorganic cation homeostasis	Any process involved in the maintenance of an internal steady state of trivalent cations at the level of a cell.	tmpzr1t_l9r_go_relaxed.owl						Note that this term was split from 'cellular di-, tri-valent inorganic cation homeostasis ; GO:0030005' (sibling term 'cellular divalent inorganic cation homeostasis' ; GO:0072503').		mah	2010-12-16T01:26:43Z					biological_process											owl:Class	
GO:0030003	biolink:NamedThing	cellular cation homeostasis	Any process involved in the maintenance of an internal steady state of cations at the level of a cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0032785	biolink:NamedThing	negative regulation of DNA-templated transcription, elongation	Any process that stops, prevents, or reduces the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides catalyzed by a DNA-dependent RNA polymerase.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of transcriptional elongation|negative regulation of DNA-dependent transcription, elongation|negative regulation of transcription elongation|negative transcription elongation regulator activity|down-regulation of RNA elongation|downregulation of RNA elongation|negative regulation of transcription elongation, DNA-dependent|down regulation of RNA elongation|inhibition of RNA elongation													biological_process											owl:Class	
GO:0000782	biolink:NamedThing	telomere cap complex	A complex of DNA and protein located at the end of a linear chromosome that protects and stabilizes a linear chromosome.	tmpzr1t_l9r_go_relaxed.owl						Note that this term can be used in place of the obsolete cellular component term 'telomere ; GO:0005696'. Use with caution because this term refers to a specific protein complex and not a region of the chromosome.								cellular_component											owl:Class	
GO:0050986	biolink:NamedThing	isopeptide cross-linking via N-(L-isoglutamyl)-glycine	The formation of an isopeptide cross-link between peptidyl-glutamate and peptidyl-glycine to produce N-(L-isoglutamyl)-glycine, as found in the antibiotic microcin J25.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0360									biological_process											owl:Class	
GO:0018262	biolink:NamedThing	isopeptide cross-linking	The formation of a covalent cross-link between or within peptide chains, where either the amino group or the carboxyl group, or both, are not attached to the alpha carbon.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0046798	biolink:NamedThing	viral portal complex	A multimeric ring of proteins through which the DNA enters and exits the viral capsid.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0016042	biolink:NamedThing	lipid catabolic process	The chemical reactions and pathways resulting in the breakdown of lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent.	tmpzr1t_l9r_go_relaxed.owl	multicellular organism lipid catabolic process|lipid catabolism|lipid degradation|lipid breakdown|lipolysis|multicellular organismal lipid catabolic process				Wikipedia:Lipid_catabolism							GO:0006724|GO:0044240		biological_process											owl:Class	
GO:0070979	biolink:NamedThing	protein K11-linked ubiquitination	A protein ubiquitination process in which ubiquitin monomers are attached to a protein, and then ubiquitin polymers are formed by linkages between lysine residues at position 11 of the ubiquitin monomers. K11-linked polyubiquitination targets the substrate protein for degradation. The anaphase-promoting complex promotes the degradation of mitotic regulators by assembling K11-linked polyubiquitin chains.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-10-26T04:50:57Z					biological_process											owl:Class	
GO:0001927	biolink:NamedThing	exocyst assembly	The aggregation, arrangement and bonding together of various polypeptides into the exocyst complex.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0060377	biolink:NamedThing	negative regulation of mast cell differentiation	Any process that decreases the rate, frequency or extent of mast cell differentiation, the process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of a mast cell. A mast cell is a cell that is found in almost all tissues containing numerous basophilic granules and capable of releasing large amounts of histamine and heparin upon activation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0002762	biolink:NamedThing	negative regulation of myeloid leukocyte differentiation	Any process that stops, prevents, or reduces the frequency, rate, or extent of myeloid leukocyte differentiation.	tmpzr1t_l9r_go_relaxed.owl	downregulation of myeloid leukocyte differentiation|inhibition of myeloid leukocyte differentiation|down-regulation of myeloid leukocyte differentiation|down regulation of myeloid leukocyte differentiation													biological_process											owl:Class	
GO:0050033	biolink:NamedThing	L-rhamnono-1,4-lactonase activity	Catalysis of the reaction: L-rhamnono-1,4-lactone + H(2)O = L-rhamnonate + H(+).	tmpzr1t_l9r_go_relaxed.owl	L-rhamno-gamma-lactonase activity|L-rhamnono-gamma-lactonase activity|L-rhamnono-1,4-lactone lactonohydrolase activity				RHEA:10288|EC:3.1.1.65|KEGG_REACTION:R03772|MetaCyc:L-RHAMNONO-14-LACTONASE-RXN									molecular_function											owl:Class	
GO:1905888	biolink:NamedThing	negative regulation of cellular response to very-low-density lipoprotein particle stimulus	Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to very-low-density lipoprotein particle stimulus.	tmpzr1t_l9r_go_relaxed.owl	inhibition of cellular response to very-low-density lipoprotein particle stimulus|inhibition of cellular response to VLDL particle stimulus|down-regulation of cellular response to very-low-density lipoprotein particle stimulus|down regulation of cellular response to VLDL particle stimulus|down-regulation of cellular response to VLDL particle stimulus|downregulation of cellular response to VLDL particle stimulus|downregulation of cellular response to very-low-density lipoprotein particle stimulus|down regulation of cellular response to very-low-density lipoprotein particle stimulus|negative regulation of cellular response to VLDL particle stimulus							bc	2017-02-01T10:09:25Z					biological_process											owl:Class	
GO:1905890	biolink:NamedThing	regulation of cellular response to very-low-density lipoprotein particle stimulus	Any process that modulates the frequency, rate or extent of cellular response to very-low-density lipoprotein particle stimulus.	tmpzr1t_l9r_go_relaxed.owl	regulation of cellular response to VLDL particle stimulus							bc	2017-02-01T10:09:16Z					biological_process											owl:Class	
GO:1900125	biolink:NamedThing	regulation of hyaluronan biosynthetic process	Any process that modulates the frequency, rate or extent of hyaluronan biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of hyaluronan anabolism|regulation of hyaluronan formation|regulation of hyaluronan synthesis|regulation of hyaluronan biosynthesis							yaf	2012-02-23T01:09:21Z					biological_process											owl:Class	
GO:1905869	biolink:NamedThing	negative regulation of 3'-UTR-mediated mRNA stabilization	Any process that stops, prevents or reduces the frequency, rate or extent of 3'-UTR-mediated mRNA stabilization.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of 3'-UTR-mediated mRNA stabilization|down regulation of 3'-UTR-mediated mRNA stabilization|down-regulation of 3'-untranslated region-mediated mRNA stabilization|downregulation of 3'-untranslated region-mediated mRNA stabilization|down regulation of 3'-untranslated region-mediated mRNA stabilization|negative regulation of 3'-untranslated region-mediated mRNA stabilization|inhibition of 3'-UTR-mediated mRNA stabilization|downregulation of 3'-UTR-mediated mRNA stabilization|inhibition of 3'-untranslated region-mediated mRNA stabilization							rz	2017-01-27T11:51:46Z					biological_process											owl:Class	
GO:0050698	biolink:NamedThing	proteoglycan sulfotransferase activity	Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + proteoglycan = adenosine 3',5'-bisphosphate + proteoglycan sulfate. A proteoglycan is a glycoprotein whose carbohydrate units are glycosaminoglycans.	tmpzr1t_l9r_go_relaxed.owl	proteoglycan sulphotransferase activity|proteoglycan sulfate transfer													molecular_function											owl:Class	
GO:0010166	biolink:NamedThing	wax metabolic process	The chemical reactions and pathways involving wax, a compound containing C16 and C18 fatty acids.	tmpzr1t_l9r_go_relaxed.owl	wax metabolism													biological_process											owl:Class	
GO:0001178	biolink:NamedThing	regulation of transcriptional start site selection at RNA polymerase II promoter	Any process that modulates the rate, frequency or extent of a process involved in the selection of the specific location within the template strand of an RNA polymerase II promoter for hybridization of the cognate ribonucleotides and formation of first phosphodiester bond within the nascent transcript.	tmpzr1t_l9r_go_relaxed.owl	regulation of transcription start site selection at RNA polymerase II promoter							krc	2011-06-20T02:06:00Z					biological_process											owl:Class	
GO:0060260	biolink:NamedThing	regulation of transcription initiation from RNA polymerase II promoter	Any process that modulates the rate, frequency or extent of a process involved in starting transcription from an RNA polymerase II promoter.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0060400	biolink:NamedThing	negative regulation of growth hormone receptor signaling pathway	Any process that decreases the rate, frequency or extent of the growth hormone receptor signaling pathway. The growth hormone receptor signaling pathway is the series of molecular signals generated as a consequence of growth hormone receptor binding to its physiological ligand.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of growth hormone receptor signalling pathway													biological_process											owl:Class	
GO:0071688	biolink:NamedThing	striated muscle myosin thick filament assembly	The aggregation, arrangement and bonding together of proteins to form the myosin-based thick filaments of myofibrils in striated muscle.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-02-25T03:52:21Z					biological_process											owl:Class	
GO:0018163	biolink:NamedThing	protein-DNA covalent cross-linking via the 5'-end to peptidyl-tyrosine	The formation of a covalent cross-link between DNA and a peptidyl-tyrosine residue by the formation of O4'-(phospho-5'-DNA)-L-tyrosine.	tmpzr1t_l9r_go_relaxed.owl	DNA-protein covalent cross-linking via the 5' end to peptidyl-tyrosine				RESID:AA0254									biological_process											owl:Class	
GO:0045327	biolink:NamedThing	protein-DNA covalent cross-linking via peptidyl-tyrosine	The formation of a covalent cross-link between DNA and a peptidyl-tyrosine residue.	tmpzr1t_l9r_go_relaxed.owl	DNA-protein covalent cross-linking via peptidyl-tyrosine													biological_process											owl:Class	
GO:0045541	biolink:NamedThing	negative regulation of cholesterol biosynthetic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cholesterol.	tmpzr1t_l9r_go_relaxed.owl	down regulation of cholesterol biosynthetic process|negative regulation of cholesterol anabolism|negative regulation of cholesterol synthesis|down-regulation of cholesterol biosynthetic process|negative regulation of cholesterol biosynthesis|negative regulation of cholesterol formation|downregulation of cholesterol biosynthetic process|inhibition of cholesterol biosynthetic process													biological_process											owl:Class	
GO:0051953	biolink:NamedThing	negative regulation of amine transport	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of amines into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	downregulation of amine transport|down-regulation of amine transport|inhibition of amine transport|down regulation of amine transport													biological_process											owl:Class	
GO:0048813	biolink:NamedThing	dendrite morphogenesis	The process in which the anatomical structures of a dendrite are generated and organized.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0018965	biolink:NamedThing	s-triazine compound metabolic process	The chemical reactions and pathways involving any s-triazine compound. These compounds include many pesticides of widespread use in agriculture, and are characterized by a symmetrical hexameric ring consisting of alternating carbon and nitrogen atoms.	tmpzr1t_l9r_go_relaxed.owl	s-triazine compound metabolism				UM-BBD_pathwayID:tria									biological_process											owl:Class	
GO:0150015	biolink:NamedThing	apical proximal dendrite	The dendrite of the dendritic tree, which emerges near the apical pole of a neuron, and which is the closest to the cell body of the neuron (the soma).	tmpzr1t_l9r_go_relaxed.owl								bc	2017-12-21T12:09:26Z					cellular_component											owl:Class	
GO:1990635	biolink:NamedThing	proximal dendrite	The dendrite of the dendritic tree that is closest to the neuronal cell body (the soma).	tmpzr1t_l9r_go_relaxed.owl								sl	2015-02-10T22:57:16Z					cellular_component											owl:Class	
GO:0045461	biolink:NamedThing	sterigmatocystin biosynthetic process	The chemical reactions and pathways resulting in the formation of sterigmatocystin, a carcinogenic mycotoxin produced in high yields by strains of the common molds.	tmpzr1t_l9r_go_relaxed.owl	sterigmatocystin formation|sterigmatocystin anabolism|sterigmatocystin biosynthesis|sterigmatocystin synthesis													biological_process											owl:Class	
GO:2000836	biolink:NamedThing	positive regulation of androgen secretion	Any process that activates or increases the frequency, rate or extent of androgen secretion.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-07-26T08:39:51Z					biological_process											owl:Class	
GO:2000834	biolink:NamedThing	regulation of androgen secretion	Any process that modulates the frequency, rate or extent of androgen secretion.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-07-26T08:39:45Z					biological_process											owl:Class	
GO:1901160	biolink:NamedThing	primary amino compound metabolic process	The chemical reactions and pathways involving primary amino compound.	tmpzr1t_l9r_go_relaxed.owl	primary amino compound metabolism							bf	2012-07-18T04:44:39Z					biological_process											owl:Class	
GO:0032336	biolink:NamedThing	negative regulation of activin secretion	Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of activin from a cell.	tmpzr1t_l9r_go_relaxed.owl	inhibition of activin secretion|down regulation of activin secretion|downregulation of activin secretion|down-regulation of activin secretion													biological_process											owl:Class	
GO:0002124	biolink:NamedThing	territorial aggressive behavior	Aggressive behavior performed in defence of a fixed area against intruders, typically conspecifics.	tmpzr1t_l9r_go_relaxed.owl	territorial aggression													biological_process											owl:Class	
GO:0002118	biolink:NamedThing	aggressive behavior	A behavioral interaction between organisms in which one organism has the intention of inflicting physical damage on another individual.	tmpzr1t_l9r_go_relaxed.owl	aggression				Wikipedia:Aggression									biological_process											owl:Class	
GO:0005369	biolink:NamedThing	taurine:sodium symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: taurine(out) + Na+(out) = taurine(in) + Na+(in).	tmpzr1t_l9r_go_relaxed.owl	sodium/chloride-dependent taurine transporter													molecular_function											owl:Class	
GO:0005368	biolink:NamedThing	taurine transmembrane transporter activity	Enables the transfer of taurine from one side of a membrane to the other. Taurine (2-aminoethanesulfonic acid) is a sulphur-containing amino acid derivative which is important in the metabolism of fats.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1905774	biolink:NamedThing	regulation of DNA helicase activity	Any process that modulates the frequency, rate or extent of ATP-dependent DNA helicase activity.	tmpzr1t_l9r_go_relaxed.owl	regulation of ATP-dependent DNA helicase activity							rb	2013-10-15T21:19:52Z			GO:1902449		biological_process											owl:Class	
GO:1905462	biolink:NamedThing	regulation of DNA duplex unwinding	Any process that modulates the frequency, rate or extent of DNA duplex unwinding.	tmpzr1t_l9r_go_relaxed.owl	regulation of duplex DNA melting|regulation of DNA unwinding							ans	2016-09-19T11:58:41Z					biological_process											owl:Class	
GO:1903784	biolink:NamedThing	positive regulation of sodium ion import across plasma membrane	Any process that activates or increases the frequency, rate or extent of sodium ion import across the plasma membrane.	tmpzr1t_l9r_go_relaxed.owl	upregulation of sodium ion import across plasma membrane|up-regulation of sodium ion import across plasma membrane|up regulation of sodium ion import across plasma membrane|activation of sodium ion import across plasma membrane							nc	2015-01-07T16:49:00Z					biological_process											owl:Class	
GO:1902307	biolink:NamedThing	positive regulation of sodium ion transmembrane transport	Any process that activates or increases the frequency, rate or extent of sodium ion transmembrane transport.	tmpzr1t_l9r_go_relaxed.owl	activation of sodium ion transmembrane transport|upregulation of sodium ion membrane transport|activation of sodium ion membrane transport|positive regulation of sodium ion membrane transport|up-regulation of sodium ion membrane transport|up regulation of sodium ion membrane transport|up-regulation of sodium ion transmembrane transport|up regulation of sodium ion transmembrane transport|upregulation of sodium ion transmembrane transport							rl	2013-07-18T13:34:18Z					biological_process											owl:Class	
GO:1904062	biolink:NamedThing	regulation of cation transmembrane transport	Any process that modulates the frequency, rate or extent of cation transmembrane transport.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-03-18T21:11:43Z					biological_process											owl:Class	
GO:1902193	biolink:NamedThing	2-methylbut-2-enoyl-CoA(4-) catabolic process	The chemical reactions and pathways resulting in the breakdown of 2-methylbut-2-enoyl-CoA(4-).	tmpzr1t_l9r_go_relaxed.owl	2-methylbut-2-enoyl-CoA(4-) breakdown|2-methylbut-2-enoyl-CoA(4-) catabolism|2-methylbut-2-enoyl-CoA(4-) degradation							ms	2013-06-06T09:40:41Z					biological_process											owl:Class	
GO:1903377	biolink:NamedThing	negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway	Any process that stops, prevents or reduces the frequency, rate or extent of oxidative stress-induced neuron intrinsic apoptotic signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of oxidative stress-induced neuron apoptosis|down regulation of neuron intrinsic apoptotic signaling pathway in response to oxidative stress|negative regulation of neuron intrinsic apoptotic signaling pathway in response to oxidative stress|downregulation of neuron apoptosis in response to oxidative stress|down regulation of neuron apoptosis in response to oxidative stress|downregulation of neuron intrinsic apoptotic signaling pathway in response to oxidative stress|down-regulation of neuron intrinsic apoptotic signaling pathway in response to oxidative stress|neuroprotection against oxidative stress-induced apoptosis|inhibition of neuron apoptosis in response to oxidative stress|protection against oxidative stress-induced neuronal apoptosis|down-regulation of neuron apoptosis in response to oxidative stress|negative regulation of neuron apoptosis in response to oxidative stress|protection against oxidative stress-induced neuron apoptosis|inhibition of neuron intrinsic apoptotic signaling pathway in response to oxidative stress							bf	2014-08-26T13:03:28Z					biological_process											owl:Class	
GO:1905036	biolink:NamedThing	positive regulation of antifungal innate immune response	Any process that activates or increases the frequency, rate or extent of an antifungal innate immune response.	tmpzr1t_l9r_go_relaxed.owl	upregulation of antifungal innate immune response|up regulation of antifungal innate immune response|up-regulation of antifungal innate immune response|activation of antifungal innate immune response							dph	2016-03-07T20:08:26Z					biological_process											owl:Class	
GO:1905034	biolink:NamedThing	regulation of antifungal innate immune response	Any process that modulates the frequency, rate or extent of an antifungal innate immune response.	tmpzr1t_l9r_go_relaxed.owl								dph	2016-03-07T20:07:54Z					biological_process											owl:Class	
GO:0005976	biolink:NamedThing	polysaccharide metabolic process	The chemical reactions and pathways involving a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically.	tmpzr1t_l9r_go_relaxed.owl	glycan metabolic process|multicellular organismal polysaccharide metabolic process|polysaccharide metabolism|glycan metabolism											GO:0044263		biological_process											owl:Class	
GO:0005975	biolink:NamedThing	carbohydrate metabolic process	The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y. Includes the formation of carbohydrate derivatives by the addition of a carbohydrate residue to another molecule.	tmpzr1t_l9r_go_relaxed.owl	multicellular organismal carbohydrate metabolic process|carbohydrate metabolism|single-organism carbohydrate metabolic process				Wikipedia:Carbohydrate_metabolism			jl	2012-10-23T15:40:34Z			GO:0044261|GO:0044723		biological_process											owl:Class	
GO:0032074	biolink:NamedThing	negative regulation of nuclease activity	Any process that stops or reduces the rate of nuclease activity, the hydrolysis of ester linkages within nucleic acids.	tmpzr1t_l9r_go_relaxed.owl	downregulation of nuclease activity|down regulation of nuclease activity|nuclease inhibitor|down-regulation of nuclease activity|inhibition of nuclease activity													biological_process											owl:Class	
GO:1905406	biolink:NamedThing	positive regulation of mitotic cohesin loading	Any process that activates or increases the frequency, rate or extent of mitotic cohesin loading.	tmpzr1t_l9r_go_relaxed.owl								vw	2016-08-25T14:49:01Z					biological_process											owl:Class	
GO:1905405	biolink:NamedThing	regulation of mitotic cohesin loading	Any process that modulates the frequency, rate or extent of mitotic cohesin loading.	tmpzr1t_l9r_go_relaxed.owl								vw	2016-08-25T14:48:46Z					biological_process											owl:Class	
GO:0060475	biolink:NamedThing	positive regulation of actin filament polymerization involved in acrosome reaction	Any process that activates or increases the frequency, rate or extent of actin polymerization as part of the acrosome reaction.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of actin polymerization involved in acrosome reaction													biological_process											owl:Class	
GO:1905489	biolink:NamedThing	regulation of sensory neuron axon guidance	Any process that modulates the frequency, rate or extent of sensory neuron axon guidance.	tmpzr1t_l9r_go_relaxed.owl								hbye	2016-09-23T13:18:56Z					biological_process											owl:Class	
GO:0002845	biolink:NamedThing	positive regulation of tolerance induction to tumor cell	Any process that activates or increases the frequency, rate, or extent of tolerance induction to tumor cell.	tmpzr1t_l9r_go_relaxed.owl	activation of tolerance induction to tumor cell|stimulation of tolerance induction to tumor cell|up-regulation of tolerance induction to tumor cell|positive regulation of tolerance induction to tumour cell|up regulation of tolerance induction to tumor cell|upregulation of tolerance induction to tumor cell													biological_process											owl:Class	
GO:2000753	biolink:NamedThing	positive regulation of glucosylceramide catabolic process	Any process that activates or increases the frequency, rate or extent of glucosylceramide catabolic process.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of glucosylceramide breakdown|positive regulation of glucosylceramide catabolism|positive regulation of glucosylceramide degradation							rl	2011-06-16T03:12:09Z					biological_process											owl:Class	
GO:0086064	biolink:NamedThing	cell communication by electrical coupling involved in cardiac conduction	The process that mediates signaling interactions between one cell and another cell by transfer of current between their adjacent cytoplasms via intercellular protein channels and contributes to the process of cardiac conduction.	tmpzr1t_l9r_go_relaxed.owl								dph	2011-11-22T08:49:44Z					biological_process											owl:Class	
GO:2000296	biolink:NamedThing	negative regulation of hydrogen peroxide catabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of hydrogen peroxide catabolic process.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of hydrogen peroxide degradation|negative regulation of hydrogen peroxide catabolism|negative regulation of detoxification of hydrogen peroxide|negative regulation of hydrogen peroxide breakdown|negative regulation of hydrogen peroxide removal|negative regulation of detoxification of H2O2|negative regulation of hydrogen peroxide scavenging|negative regulation of H2O2 catabolic process|negative regulation of H2O2 scavenging							rl	2010-12-21T03:30:55Z					biological_process											owl:Class	
GO:0003255	biolink:NamedThing	endocardial precursor cell differentiation	The process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of an endocardial precursor cell. A endocardial precursor cell is a cell that has been committed to a endocardial cell fate, but will undergo further cell divisions rather than terminally differentiate.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-10-15T12:09:43Z					biological_process											owl:Class	
GO:0039587	biolink:NamedThing	suppression by virus of host tetherin activity	Any process in which a virus stops, prevents, or reduces the activity of host tetherin activity. Tetherin (also known as BST2) is an alpha interferon-inducible cellular factor that impairs the release of many enveloped viruses. By blocking tetherin activity, many viruses circumvent its antiviral effects.	tmpzr1t_l9r_go_relaxed.owl	inhibition of host BST2/Tetherin by virus	https://github.com/geneontology/go-ontology/issues/22166						bf	2012-05-04T02:33:29Z					biological_process											owl:Class	
GO:1905616	biolink:NamedThing	regulation of miRNA-mediated gene silencing by inhibition of translation	Any process that modulates the frequency, rate or extent of miRNA-mediated gene silencing by inhibition of translation.	tmpzr1t_l9r_go_relaxed.owl	regulation of inhibition of translation involved in gene silencing by miRNA|regulation of down-regulation of translation involved in gene silencing by miRNA|regulation of gene silencing by miRNA, negative regulation of translation|regulation of miRNA-mediated gene silencing, negative regulation of translation|regulation of down regulation of translation involved in gene silencing by miRNA|regulation of downregulation of translation involved in gene silencing by miRNA|regulation of negative regulation of translation involved in gene silencing by microRNA|regulation of miRNA mediated inhibition of translation	https://github.com/geneontology/go-ontology/issues/22389						bc	2016-10-28T11:47:49Z					biological_process											owl:Class	
GO:0045589	biolink:NamedThing	regulation of regulatory T cell differentiation	Any process that modulates the frequency, rate or extent of differentiation of regulatory T cells.	tmpzr1t_l9r_go_relaxed.owl	regulation of regulatory T-lymphocyte differentiation|regulation of suppressor T lymphocyte differentiation|regulation of regulatory T cell development|regulation of regulatory T-cell differentiation|regulation of regulatory T lymphocyte differentiation|regulation of suppressor T-cell differentiation|regulation of suppressor T cell differentiation|regulation of suppressor T-lymphocyte differentiation					Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.								biological_process											owl:Class	
GO:0015835	biolink:NamedThing	peptidoglycan transport	The directed movement of peptidoglycans, a class of glycoconjugates found in bacterial cell walls, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	murein transport													biological_process											owl:Class	
GO:0002671	biolink:NamedThing	negative regulation of B cell anergy	Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell anergy.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of B-cell anergy|negative regulation of B lymphocyte anergy|down-regulation of B cell anergy|inhibition of B cell anergy|downregulation of B cell anergy|negative regulation of B-lymphocyte anergy|down regulation of B cell anergy													biological_process											owl:Class	
GO:0002912	biolink:NamedThing	negative regulation of lymphocyte anergy	Any process that stops, prevents, or reduces the frequency, rate, or extent of lymphocyte anergy.	tmpzr1t_l9r_go_relaxed.owl	downregulation of lymphocyte anergy|down-regulation of lymphocyte anergy|down regulation of lymphocyte anergy|inhibition of lymphocyte anergy													biological_process											owl:Class	
GO:0006253	biolink:NamedThing	dCTP catabolic process	The chemical reactions and pathways resulting in the breakdown of dCTP, deoxycytidine triphosphate.	tmpzr1t_l9r_go_relaxed.owl	dCTP catabolism|dCTP breakdown|dCTP degradation													biological_process											owl:Class	
GO:0046065	biolink:NamedThing	dCTP metabolic process	The chemical reactions and pathways involving dCTP, deoxycytidine triphosphate.	tmpzr1t_l9r_go_relaxed.owl	dCTP metabolism													biological_process											owl:Class	
GO:0051619	biolink:NamedThing	inhibition of histamine uptake	Any process that prevents the activation of the directed movement of histamine into a cell.	tmpzr1t_l9r_go_relaxed.owl	inhibition of histamine import													biological_process											owl:Class	
GO:0051617	biolink:NamedThing	negative regulation of histamine uptake	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of histamine into a cell.	tmpzr1t_l9r_go_relaxed.owl	down regulation of histamine uptake|negative regulation of histamine import|down-regulation of histamine uptake|downregulation of histamine uptake													biological_process											owl:Class	
GO:0004046	biolink:NamedThing	aminoacylase activity	Catalysis of the reaction: an N-acyl-L-amino acid + H2O = a carboxylate + an L-amino acid.	tmpzr1t_l9r_go_relaxed.owl	histozyme activity|hippurase activity|L-amino-acid acylase activity|acylase I activity|aminoacylase I activity|L-aminoacylase activity|long acyl amidoacylase activity|alpha-N-acylaminoacid hydrolase activity|amido acid deacylase activity|N-acyl-L-amino-acid amidohydrolase activity|dehydropeptidase II activity|benzamidase activity|short acyl amidoacylase activity				RHEA:15565|MetaCyc:AMINOACYLASE-RXN|Reactome:R-HSA-5433074|Reactome:R-HSA-5579081|Reactome:R-HSA-9638046|EC:3.5.1.14									molecular_function											owl:Class	
GO:0050598	biolink:NamedThing	taxane 13-alpha-hydroxylase activity	Catalysis of the reaction: H(+) + NADPH + O(2) + taxa-4(20),11-dien-5alpha-ol = H(2)O + NADP(+) + taxa-4(20),11-dien-5alpha,13alpha-diol.	tmpzr1t_l9r_go_relaxed.owl	taxane 13a-hydroxylase activity|taxa-4(20),11-dien-5alpha-ol,NADPH:oxygen oxidoreductase (13alpha-hydroxylating)|taxane 13alpha-hydroxylase activity				KEGG_REACTION:R06308|EC:1.14.14.106|RHEA:18949|MetaCyc:1.14.13.77-RXN									molecular_function											owl:Class	
GO:0042128	biolink:NamedThing	nitrate assimilation	The nitrogen metabolic process that encompasses the uptake of nitrate from the environment and reduction to ammonia, and results in the incorporation of nitrogen derived from nitrate into cellular substances.	tmpzr1t_l9r_go_relaxed.owl	assimilatory nitrate reduction				MetaCyc:PWY-381									biological_process											owl:Class	
GO:0071941	biolink:NamedThing	nitrogen cycle metabolic process	A nitrogen compound metabolic process that contributes to the nitrogen cycle. The nitrogen cycle is a series of metabolic pathways by which nitrogen is converted between various forms and redox states; it encompasses pathways in which nitrogen is acted upon directly, such as nitrification, denitrification, nitrogen fixation, and mineralization.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Nitrogen_cycle			mah	2010-09-30T05:21:03Z					biological_process											owl:Class	
GO:0050211	biolink:NamedThing	procollagen galactosyltransferase activity	Catalysis of the reaction: UDP-galactose + procollagen 5-hydroxy-L-lysine = UDP + procollagen 5-(D-galactosyloxy)-L-lysine.	tmpzr1t_l9r_go_relaxed.owl	UDPgalactose:procollagen-5-hydroxy-L-lysine D-galactosyltransferase activity|collagen hydroxylysyl galactosyltransferase activity|uridine diphosphogalactose-collagen galactosyltransferase activity|UDP-galactose:procollagen-5-hydroxy-L-lysine D-galactosyltransferase activity|UDPgalactose:5-hydroxylysine-collagen galactosyltransferase activity|collagen galactosyltransferase activity|UDP galactose-collagen galactosyltransferase activity|hydroxylysine galactosyltransferase activity				EC:2.4.1.50|Reactome:R-HSA-1981120|MetaCyc:PROCOLLAGEN-GALACTOSYLTRANSFERASE-RXN|RHEA:12637|Reactome:R-HSA-1981128									molecular_function											owl:Class	
GO:1902841	biolink:NamedThing	regulation of netrin-activated signaling pathway	Any process that modulates the frequency, rate or extent of netrin-activated signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	regulation of netrin signaling pathway|regulation of netrin-activated signalling pathway|regulation of netrin-mediated signaling pathway|regulation of netrin-activated signal transduction pathway							kmv	2014-04-01T15:24:46Z					biological_process											owl:Class	
GO:0014068	biolink:NamedThing	positive regulation of phosphatidylinositol 3-kinase signaling	Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the phosphatidylinositol 3-kinase cascade.	tmpzr1t_l9r_go_relaxed.owl	activation of phosphoinositide 3-kinase cascade|positive regulation of PI3K cascade|positive regulation of phosphatidylinositol 3-kinase cascade|up regulation of phosphatidylinositol 3-kinase cascade|stimulation of phosphatidylinositol 3-kinase cascade|upregulation of phosphatidylinositol 3-kinase cascade|up-regulation of phosphatidylinositol 3-kinase cascade|positive regulation of PI 3-kinase cascade|positive regulation of phosphoinositide 3-kinase cascade													biological_process											owl:Class	
GO:0014066	biolink:NamedThing	regulation of phosphatidylinositol 3-kinase signaling	Any process that modulates the frequency, rate or extent of signal transduction mediated by the phosphatidylinositol 3-kinase cascade.	tmpzr1t_l9r_go_relaxed.owl	regulation of PI3K cascade|regulation of phosphoinositide 3-kinase cascade|regulation of phosphatidylinositol 3-kinase cascade|regulation of PI 3-kinase cascade													biological_process											owl:Class	
GO:0045443	biolink:NamedThing	juvenile hormone secretion	The regulated release of juvenile hormones, the three sesquiterpenoid derivatives that function to maintain the larval state of insects at molting and that may be required for other processes, e.g. oogenesis.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0000154	biolink:NamedThing	rRNA modification	The covalent alteration of one or more nucleotides within an rRNA molecule to produce an rRNA molecule with a sequence that differs from that coded genetically.	tmpzr1t_l9r_go_relaxed.owl	rRNA editing					The term 'RNA editing' (GO:0016547) was merged into 'RNA modification' (GO:0009451) on the basis of statements in the preface of Modification and Editing of RNA (ISBN:1555811337) that there is no clear distinction between modification and editing. Parallel changes were made for substrate (e.g. tRNA, rRNA, etc.) specific child terms of 'RNA editing'.						GO:0016548		biological_process											owl:Class	
GO:2000585	biolink:NamedThing	positive regulation of platelet-derived growth factor receptor-alpha signaling pathway	Any process that activates or increases the frequency, rate or extent of platelet-derived growth factor receptor-alpha signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of PDGF receptor-alpha signaling pathway|positive regulation of PDGFR-alpha signaling pathway|positive regulation of platelet-derived growth factor receptor-alpha signalling pathway|positive regulation of alphaPDGF receptor signaling pathway							bf	2011-04-07T03:26:35Z					biological_process											owl:Class	
GO:2000583	biolink:NamedThing	regulation of platelet-derived growth factor receptor-alpha signaling pathway	Any process that modulates the frequency, rate or extent of platelet-derived growth factor receptor-alpha signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	regulation of platelet-derived growth factor receptor-alpha signalling pathway|regulation of PDGF receptor-alpha signaling pathway|regulation of PDGFR-alpha signaling pathway|regulation of alphaPDGF receptor signaling pathway							bf	2011-04-07T03:26:25Z					biological_process											owl:Class	
GO:0001580	biolink:NamedThing	detection of chemical stimulus involved in sensory perception of bitter taste	The series of events required for a bitter taste stimulus to be received and converted to a molecular signal.	tmpzr1t_l9r_go_relaxed.owl	sensory transduction of bitter taste|sensory transduction of chemical stimulus during perception of bitter taste|sensory detection of bitter taste|perception of bitter taste, detection of chemical stimulus|sensory detection of chemical stimulus during perception of bitter taste|bitter taste detection|perception of bitter taste, sensory transduction of chemical stimulus													biological_process											owl:Class	
GO:1904871	biolink:NamedThing	positive regulation of protein localization to Cajal body	Any process that activates or increases the frequency, rate or extent of protein localization to Cajal body.	tmpzr1t_l9r_go_relaxed.owl	up regulation of protein localisation to Cajal body|up-regulation of protein localization to Cajal body|upregulation of protein localization in Cajal body|up-regulation of protein localization in Cajal body|positive regulation of protein localization in Cajal body|up regulation of protein localization to Cajal body|positive regulation of protein localisation in Cajal body|upregulation of protein localisation in Cajal body|activation of protein localization to Cajal body|up regulation of protein localization in Cajal body|up-regulation of protein localisation in Cajal body|upregulation of protein localization to Cajal body|activation of protein localization in Cajal body|upregulation of protein localisation to Cajal body|positive regulation of protein localisation to Cajal body|activation of protein localisation to Cajal body|activation of protein localisation in Cajal body|up regulation of protein localisation in Cajal body|up-regulation of protein localisation to Cajal body							nc	2015-12-18T11:17:45Z					biological_process											owl:Class	
GO:1900182	biolink:NamedThing	positive regulation of protein localization to nucleus	Any process that activates or increases the frequency, rate or extent of protein localization to nucleus.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of protein localization in nucleus|activation of protein localisation to nucleus|up regulation of protein localization in nucleus|activation of protein localization to nucleus|activation of protein localization in nucleus|up regulation of protein localization in cell nucleus|upregulation of protein localization to nucleus|positive regulation of protein localization in cell nucleus|up regulation of protein localisation to nucleus|upregulation of protein localisation to nucleus|activation of protein localization in cell nucleus|upregulation of protein localization in nucleus|positive regulation of protein localisation to nucleus|upregulation of protein localization in cell nucleus|up-regulation of protein localization in cell nucleus|positive regulation of protein localization in nucleus|up-regulation of protein localization to nucleus|up-regulation of protein localisation to nucleus|up regulation of protein localization to nucleus							bf	2012-03-12T01:23:52Z					biological_process											owl:Class	
GO:0046654	biolink:NamedThing	tetrahydrofolate biosynthetic process	The chemical reactions and pathways resulting in the formation of tetrahydrofolate, 5,6,7,8-tetrahydrofolic acid, a folate derivative bearing additional hydrogens on the pterin group.	tmpzr1t_l9r_go_relaxed.owl	tetrahydrofolate synthesis|tetrahydrofolate formation|tetrahydrofolate biosynthesis|tetrahydrofolate anabolism				MetaCyc:FOLSYN-PWY									biological_process											owl:Class	
GO:0046653	biolink:NamedThing	tetrahydrofolate metabolic process	The chemical reactions and pathways involving tetrahydrofolate, 5,6,7,8-tetrahydrofolic acid, a folate derivative bearing additional hydrogens on the pterin group.	tmpzr1t_l9r_go_relaxed.owl	tetrahydrofolate metabolism													biological_process											owl:Class	
GO:0099026	biolink:NamedThing	anchored component of presynaptic membrane	The component of the presynaptic membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping.	tmpzr1t_l9r_go_relaxed.owl	anchored component of presynaptic plasma membrane													cellular_component											owl:Class	
GO:0098889	biolink:NamedThing	intrinsic component of presynaptic membrane	The component of the presynaptic membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.	tmpzr1t_l9r_go_relaxed.owl	intrinsic to presynaptic membrane													cellular_component											owl:Class	
GO:0034852	biolink:NamedThing	4,4-dimethyl-3-oxopentanal dehydrogenase activity	Catalysis of the reaction: 4,4-dimethyl-3-oxopentanal + H2O = 4,4-dimethyl-3-oxopentanoate + 3 H+ + 2 e-.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r1309									molecular_function											owl:Class	
GO:0102297	biolink:NamedThing	selenate adenylyltransferase activity	Catalysis of the reaction: selenic acid + ATP + 2 H+ <=> adenylyl selenate + diphosphoric acid.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-12720									molecular_function											owl:Class	
GO:0016779	biolink:NamedThing	nucleotidyltransferase activity	Catalysis of the transfer of a nucleotidyl group to a reactant.	tmpzr1t_l9r_go_relaxed.owl					EC:2.7.7.-|Reactome:R-HSA-6782434									molecular_function											owl:Class	
GO:0052851	biolink:NamedThing	ferric-chelate reductase (NADPH) activity	Catalysis of the reaction:  2 Fe3+-siderophore + NADP(+) + H(+) -> 2 Fe2+-siderophore + NADPH.	tmpzr1t_l9r_go_relaxed.owl	ferric reductase, NADPH-dependent activity|ferric chelate reductase activity|iron chelate reductase activity	https://github.com/geneontology/go-ontology/issues/21029			RHEA:28795|KEGG_REACTION:R09541|MetaCyc:RXN0-6555|EC:1.16.1.9			ai	2011-12-05T11:04:23Z					molecular_function											owl:Class	
GO:0000293	biolink:NamedThing	ferric-chelate reductase activity	Catalysis of the reaction: 2 Fe3+-siderophore + electron donor -> 2 Fe3+-siderophore + electron acceptor.	tmpzr1t_l9r_go_relaxed.owl	ferric chelate reductase activity|iron chelate reductase activity	https://github.com/geneontology/go-ontology/issues/21029												molecular_function											owl:Class	
GO:0021678	biolink:NamedThing	third ventricle development	The process whose specific outcome is the progression of the third ventricle over time, from its formation to the mature structure. The third ventricle is the narrow cleft inferior to the corpus callosum, within the diencephalon, between the paired thalami. Its floor is formed by the hypothalamus, its anterior wall by the lamina terminalis, and its roof by ependyma, and it communicates with the fourth ventricle by the cerebral aqueduct, and with the lateral ventricles by the interventricular foramina.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0046167	biolink:NamedThing	glycerol-3-phosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of glycerol-3-phosphate, a phosphoric monoester of glycerol.	tmpzr1t_l9r_go_relaxed.owl	glycerol-3-phosphate formation|glycerol-3-phosphate biosynthesis|glycerol-3-phosphate anabolism|glycerol-3-phosphate synthesis													biological_process											owl:Class	
GO:0052067	biolink:NamedThing	antiphagocytosis	Any process in which a symbiont avoids phagocytosis by a host cell, for example a phagocyte or a macrophage. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	down regulation by symbiont of entry into host cell via phagocytosis|inhibition by symbiont of entry into host cell via phagocytosis|negative regulation by symbiont of entry into host cell via phagocytosis|negative regulation by organism of entry into cell of other organism via phagocytosis involved in symbiotic interaction|modulation by symbiont of entry into host via phagocytosis|negative regulation by organism of entry into host cell via host phagocytosis|phagocytosis avoidence|modulation by organism of entry into host via host phagocytosis|downregulation by symbiont of entry into host cell via phagocytosis|down-regulation by symbiont of entry into host cell via phagocytosis	https://github.com/geneontology/go-ontology/issues/18562|https://github.com/geneontology/go-ontology/issues/17983										GO:0052380|GO:0052483		biological_process											owl:Class	
GO:0030682	biolink:NamedThing	mitigation of host defenses by symbiont	A process by which an organism avoids or tolerates the effects of its host organism's defense response. The host defense response is mounted by the host in response to the presence of the organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	avoidance of host defenses|evasion or tolerance of host defenses|evasion of host defence response|avoidance of host defences|avoidance of defenses of other organism during symbiotic interaction|evasion or tolerance of defenses of other organism during symbiotic interaction|avoidance of defenses of other organism involved in symbiotic interaction|evasion or tolerance of defenses of other organism|evasion or tolerance of defense response of other organism involved in symbiotic interaction|evasion or tolerance of defense response of other organism during symbiotic interaction|evasion or tolerance of host defense response|evasion of other organism defence response|evasion or tolerance of defenses of other organism involved in symbiotic interaction											GO:0051807|GO:0051832|GO:0044413|GO:0044415|GO:0051834		biological_process											owl:Class	
GO:1902906	biolink:NamedThing	proteasome storage granule assembly	The aggregation, arrangement and bonding together of a set of components to form a proteasome storage granule.	tmpzr1t_l9r_go_relaxed.owl	PSG assembly|sequestration of proteasome core complex in proteasome storage granule|proteasome storage granule formation|PSG formation	https://github.com/geneontology/go-ontology/issues/20458						di	2014-04-16T01:59:41Z			GO:1990237		biological_process											owl:Class	
GO:0140694	biolink:NamedThing	non-membrane-bounded organelle assembly	The aggregation, arrangement and bonding together of a set of components to form a non-membrane-bounded organelle.	tmpzr1t_l9r_go_relaxed.owl	non-membrane-enclosed organelle assembly|non-membrane-enclosed organelle formation|non-membrane-bounded organelle formation	https://github.com/geneontology/go-ontology/issues/21939						pg	2021-08-09T15:30:06Z					biological_process											owl:Class	
GO:0045809	biolink:NamedThing	positive regulation of establishment of competence for transformation	Any process that activates or increases the frequency, rate or extent of establishment of competence for transformation.	tmpzr1t_l9r_go_relaxed.owl	up regulation of establishment of competence for transformation|activation of establishment of competence for transformation|up-regulation of establishment of competence for transformation|stimulation of establishment of competence for transformation|activator of the establishment of competence for transformation activity|upregulation of establishment of competence for transformation													biological_process											owl:Class	
GO:0045304	biolink:NamedThing	regulation of establishment of competence for transformation	Any process that modulates the frequency, rate or extent of the process in which a cell becomes able to take up and incorporate extracellular DNA into its genome.	tmpzr1t_l9r_go_relaxed.owl	regulator of establishment of competence for transformation activity													biological_process											owl:Class	
GO:0005739	biolink:NamedThing	mitochondrion	A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.	tmpzr1t_l9r_go_relaxed.owl	mitochondria				Wikipedia:Mitochondrion|NIF_Subcellular:sao1860313010	Some anaerobic or microaerophilic organisms (e.g. Entamoeba histolytica, Giardia intestinalis and several Microsporidia species) do not have mitochondria, and contain mitochondrion-related organelles (MROs) instead, called mitosomes or hydrogenosomes, very likely derived from mitochondria. To annotate gene products located in these mitochondrial relics in species such as Entamoeba histolytica, Giardia intestinalis or others, please use GO:0032047 'mitosome' or GO:0042566 'hydrogenosome'. (See PMID:24316280 for a list of species currently known to contain mitochondrion-related organelles.)								cellular_component											owl:Class	
GO:0019921	biolink:NamedThing	peptidyl-1-thioglycine biosynthetic process, carboxy-terminal	The chemical reactions and pathways resulting in the formation of carboxy-terminal peptidyl-1-thioglycine, which has a carboxy-terminal thiocarboxy-C(=O)-SH bond.	tmpzr1t_l9r_go_relaxed.owl	peptidyl-1-thioglycine formation, carboxy-terminal|peptidyl-1-thioglycine anabolism, carboxy-terminal|peptidyl-1-thioglycine synthesis, carboxy-terminal				RESID:AA0265									biological_process											owl:Class	
GO:0018173	biolink:NamedThing	peptidyl-1-thioglycine biosynthetic process from peptidyl-glycine	The chemical reactions and pathways resulting in the formation of peptidyl-1-thioglycine from other compounds, including peptidyl-glycine.	tmpzr1t_l9r_go_relaxed.owl	peptidyl-1-thioglycine synthesis from peptidyl-glycine|peptidyl-1-thioglycine formation from peptidyl-glycine|peptidyl-1-thioglycine anabolism from peptidyl-glycine				RESID:AA0265									biological_process											owl:Class	
GO:0070999	biolink:NamedThing	detection of mechanical stimulus involved in sensory perception of gravity	The series of events involved in the perception of gravity in which a sensory mechanical stimulus is received and converted into a molecular signal.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-11-03T03:27:30Z					biological_process											owl:Class	
GO:0009590	biolink:NamedThing	detection of gravity	The series of events in which a gravitational stimulus is received and converted into a molecular signal.	tmpzr1t_l9r_go_relaxed.owl	perception of gravity													biological_process											owl:Class	
GO:0060569	biolink:NamedThing	positive regulation of peptide hormone processing	Any process that increases the rate, frequency or extent of peptide hormone processing. Peptide hormone processing is the generation of a mature peptide hormone by posttranslational processing of a prohormone.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-04-29T03:22:05Z					biological_process											owl:Class	
GO:0015334	biolink:NamedThing	high-affinity oligopeptide transmembrane transporter activity	Enables the transfer of oligopeptide from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations. Oligopeptides are molecules that contain a small number (2 to 20) of amino-acid residues connected by peptide linkages.	tmpzr1t_l9r_go_relaxed.owl	high affinity oligopeptide transporter activity|high-affinity oligopeptide transporter activity													molecular_function											owl:Class	
GO:0035673	biolink:NamedThing	oligopeptide transmembrane transporter activity	Enables the transfer of oligopeptides from one side of a membrane to the other. Oligopeptides are molecules that contain a small number (2 to 20) of amino-acid residues connected by peptide linkages.	tmpzr1t_l9r_go_relaxed.owl	oligopeptide transporter activity							bf	2011-02-08T02:20:14Z			GO:0015198		molecular_function											owl:Class	
GO:1902653	biolink:NamedThing	secondary alcohol biosynthetic process	The chemical reactions and pathways resulting in the formation of secondary alcohol.	tmpzr1t_l9r_go_relaxed.owl	secondary alcohol synthesis|secondary alcohol anabolism|secondary alcohol biosynthesis|secondary alcohol formation							tt	2014-01-22T10:15:02Z					biological_process											owl:Class	
GO:0034333	biolink:NamedThing	adherens junction assembly	The aggregation, arrangement and bonding together of a set of components to form an adherens junction. An adherens junction is a cell-cell junction composed of the epithelial cadherin-catenin complex at which the cytoplasmic face of the plasma membrane is attached to actin filaments.	tmpzr1t_l9r_go_relaxed.owl	adherens junction formation													biological_process											owl:Class	
GO:0007043	biolink:NamedThing	cell-cell junction assembly	The aggregation, arrangement and bonding together of a set of components to form a junction between cells.	tmpzr1t_l9r_go_relaxed.owl	intercellular junction assembly													biological_process											owl:Class	
GO:1902327	biolink:NamedThing	bacterial-type DNA replication DNA ligation	Any DNA ligation that is involved in bacterial-type DNA replication.	tmpzr1t_l9r_go_relaxed.owl	DNA ligation involved in bacterial-type DNA replication							jl	2013-07-25T10:47:46Z					biological_process											owl:Class	
GO:0040015	biolink:NamedThing	negative regulation of multicellular organism growth	Any process that stops, prevents, or reduces the frequency, rate or extent of growth of an organism to reach its usual body size.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of body growth|negative regulation of body size													biological_process											owl:Class	
GO:0047300	biolink:NamedThing	pyridoxamine-pyruvate transaminase activity	Catalysis of the reaction: pyridoxamine + pyruvate = L-alanine + pyridoxal.	tmpzr1t_l9r_go_relaxed.owl	pyridoxamine:pyruvate aminotransferase activity|pyridoxamine--pyruvate aminotransferase activity|pyridoxamine-pyruvate aminotransferase activity|pyridoxamine-pyruvic transaminase|pyridoxamineu-pyruvic transaminase activity				KEGG_REACTION:R01712|RHEA:12841|EC:2.6.1.30|MetaCyc:2.6.1.30-RXN									molecular_function											owl:Class	
GO:0010883	biolink:NamedThing	regulation of lipid storage	Any process that modulates the rate, frequency or extent of lipid storage. Lipid storage is the accumulation and maintenance in cells or tissues of lipids, compounds soluble in organic solvents but insoluble or sparingly soluble in aqueous solvents. Lipid reserves can be accumulated during early developmental stages for mobilization and utilization at later stages of development.	tmpzr1t_l9r_go_relaxed.owl	regulation of lipid sequestration													biological_process											owl:Class	
GO:0004994	biolink:NamedThing	somatostatin receptor activity	Combining with somatostatin to initiate a change in cell activity. Somatostatin is a peptide hormone that regulates the endocrine system by signaling via G protein-coupled somatostatin receptors. Somatostatin has two active forms produced by proteolytic cleavage: a 14 amino acid peptide (SST-14) and a 28 amino acid peptide (SST-28).	tmpzr1t_l9r_go_relaxed.owl	somatotrophin release inhibiting factor receptor activity|SRIF receptor activity|GHIH receptor activity|growth hormone-inhibiting hormone receptor activity|SST receptor activity													molecular_function											owl:Class	
GO:0043680	biolink:NamedThing	filiform apparatus	A complex of cell wall invaginations in a synergid cell, similar to those in transfer cells.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0098992	biolink:NamedThing	neuronal dense core vesicle	A dense core vesicle (granule) that is part of a neuron.  These vesicles typically contain neuropeptides.  They can be found in all parts of neurons, including the soma, dendrites, axonal swellings (varicosities) and synaptic terminals.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0031045	biolink:NamedThing	dense core granule	Electron-dense organelle with a granular internal matrix; contains proteins destined to be secreted.	tmpzr1t_l9r_go_relaxed.owl	dense core vesicle				NIF_Subcellular:sao772007592									cellular_component											owl:Class	
GO:1902237	biolink:NamedThing	positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway	Any process that activates or increases the frequency, rate or extent of an endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	up regulation of endoplasmic reticulum stress-induced apoptosis|positive regulation of ER stress-induced apoptosis|positive regulation of apoptosis triggered by ER stress|positive regulation of intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress|up regulation of apoptosis in response to ER stress|positive regulation of apoptosis in response to ER stress|upregulation of endoplasmic reticulum stress-induced apoptosis|positive regulation of intrinsic apoptotic signaling pathway induced by endoplasmic reticulum stress|up-regulation of endoplasmic reticulum stress-induced apoptosis|activation of ER stress-induced apoptosis|activation of apoptosis triggered by ER stress|activation of intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress|upregulation of intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress|positive regulation of endoplasmic reticulum stress-induced apoptosis|upregulation of apoptosis triggered by ER stress|up regulation of ER stress-induced apoptosis|up regulation of apoptosis triggered by ER stress|up regulation of intrinsic apoptotic signaling pathway induced by endoplasmic reticulum stress|upregulation of ER stress-induced apoptosis|up-regulation of apoptosis in response to ER stress|up-regulation of intrinsic apoptotic signaling pathway induced by endoplasmic reticulum stress|activation of intrinsic apoptotic signaling pathway induced by endoplasmic reticulum stress|up-regulation of intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress|activation of apoptosis in response to ER stress|up-regulation of apoptosis triggered by ER stress|up regulation of intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress|upregulation of intrinsic apoptotic signaling pathway induced by endoplasmic reticulum stress|activation of endoplasmic reticulum stress-induced apoptosis|upregulation of apoptosis in response to ER stress|up-regulation of ER stress-induced apoptosis							rl	2013-06-18T15:19:49Z					biological_process											owl:Class	
GO:2001244	biolink:NamedThing	positive regulation of intrinsic apoptotic signaling pathway	Any process that activates or increases the frequency, rate or extent of intrinsic apoptotic signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of intrinsic apoptotic pathway|positive regulation of intrinsic apoptotic signalling pathway|positive regulation of mitochondrial-mediated apoptotic pathway|positive regulation of intrinsic apoptosis							pr	2011-11-24T01:36:07Z					biological_process											owl:Class	
GO:0043672	biolink:NamedThing	nexine	The inner, non-sculptured part of the exine which lies below the sexine.	tmpzr1t_l9r_go_relaxed.owl						Note that nexine is distinguished on purely morphological criteria; compare with 'endexine ; GO:0043671'. See also 'sexine ; GO:0043673'.								cellular_component											owl:Class	
GO:1901691	biolink:NamedThing	proton binding	Binding to proton.	tmpzr1t_l9r_go_relaxed.owl	hydrogen ion binding							al	2012-12-07T13:50:53Z					molecular_function											owl:Class	
GO:1900498	biolink:NamedThing	negative regulation of butyryl-CoA catabolic process to butanol	Any process that stops, prevents or reduces the frequency, rate or extent of butyryl-CoA catabolic process to butanol.	tmpzr1t_l9r_go_relaxed.owl	down regulation of butyryl-CoA catabolic process to butanol|negative regulation of butyryl-CoA catabolism to butanol|down-regulation of butyryl-CoA catabolism to butanol|downregulation of butyryl-CoA catabolism to butanol|down regulation of butyryl-CoA catabolism to butanol|inhibition of butyryl-CoA catabolic process to butanol|inhibition of butyryl-CoA catabolism to butanol|down-regulation of butyryl-CoA catabolic process to butanol|downregulation of butyryl-CoA catabolic process to butanol							tt	2012-05-02T03:53:31Z					biological_process											owl:Class	
GO:0075270	biolink:NamedThing	negative regulation of aecium development	Any process that stops, prevents, or reduces the frequency, rate or extent of aecium development, a process in which a cuplike structure containing chains of aeciospores is formed.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0034364	biolink:NamedThing	high-density lipoprotein particle	A lipoprotein particle with a high density (typically 1.063-1.21 g/ml) and a diameter of 5-10 nm that contains APOAs and may contain APOCs and APOE; found in blood and carries lipids from body tissues to the liver as part of the reverse cholesterol transport process.	tmpzr1t_l9r_go_relaxed.owl	HDL particle|HDL complex|high-density lipoprotein class complex|HDL3|HDL2													cellular_component											owl:Class	
GO:1902630	biolink:NamedThing	regulation of membrane hyperpolarization	Any process that modulates the frequency, rate or extent of membrane hyperpolarization.	tmpzr1t_l9r_go_relaxed.owl								krc	2014-01-17T18:27:56Z					biological_process											owl:Class	
GO:0031119	biolink:NamedThing	tRNA pseudouridine synthesis	The intramolecular conversion of uridine to pseudouridine in a tRNA molecule.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0047418	biolink:NamedThing	phthalyl amidase activity	Catalysis of the reaction: H2O + a phthalylamide = phthalate + substituted amine.	tmpzr1t_l9r_go_relaxed.owl	o-phthalyl amidase activity|phthalyl-amide amidohydrolase activity				MetaCyc:3.5.1.79-RXN|EC:3.5.1.79|RHEA:18297									molecular_function											owl:Class	
GO:0006798	biolink:NamedThing	polyphosphate catabolic process	The chemical reactions and pathways resulting in the breakdown of a polyphosphate, the anion or salt of polyphosphoric acid.	tmpzr1t_l9r_go_relaxed.owl	polyphosphate breakdown|polyphosphate catabolism|polyphosphate degradation													biological_process											owl:Class	
GO:0006797	biolink:NamedThing	polyphosphate metabolic process	The chemical reactions and pathways involving a polyphosphate, the anion or salt of polyphosphoric acid.	tmpzr1t_l9r_go_relaxed.owl	polyphosphate metabolism													biological_process											owl:Class	
GO:0045841	biolink:NamedThing	negative regulation of mitotic metaphase/anaphase transition	Any process that stops, prevents, or reduces the frequency, rate or extent of the cell cycle process in which a cell progresses from metaphase to anaphase during mitosis, triggered by the activation of the anaphase promoting complex by Cdc20/Sleepy homolog which results in the degradation of Securin.	tmpzr1t_l9r_go_relaxed.owl	downregulation of mitotic metaphase/anaphase transition|down-regulation of mitotic metaphase/anaphase transition|down regulation of mitotic metaphase/anaphase transition|inhibition of mitotic metaphase/anaphase transition													biological_process											owl:Class	
GO:2000816	biolink:NamedThing	negative regulation of mitotic sister chromatid separation	Any process that stops, prevents or reduces the frequency, rate or extent of mitotic sister chromatid separation.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of sister chromatid separation during mitosis|negative regulation of mitotic sister chromatid resolution|negative regulation of chromosome separation during mitosis|negative regulation of mitotic chromosome separation							mah	2011-07-11T04:45:06Z					biological_process											owl:Class	
GO:0102584	biolink:NamedThing	cyanidin 3-O-[2''-O-(xylosyl)-6''-O-(p-coumaroyl) glucoside] 5-O-glucosyltransferase activity	Catalysis of the reaction: cyanidin 3-O-[2''-O-xylosyl) 6''-O-(p-coumaroyl) glucoside + UDP-alpha-D-glucose <=> cyanidin 3-O-[2''-O-(xylosyl)-6''-O-(p-coumaroyl) glucoside] 5-O-glucoside + UDP + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-15330									molecular_function											owl:Class	
GO:1901496	biolink:NamedThing	positive regulation of cysteine metabolic process	Any process that activates or increases the frequency, rate or extent of cysteine metabolic process.	tmpzr1t_l9r_go_relaxed.owl	upregulation of cysteine metabolic process|up-regulation of cysteine metabolism|up regulation of cysteine metabolic process|upregulation of cysteine metabolism|up-regulation of cysteine metabolic process|activation of cysteine metabolic process|positive regulation of cysteine metabolism|up regulation of cysteine metabolism|activation of cysteine metabolism							vw	2012-10-16T14:28:51Z					biological_process											owl:Class	
GO:0031337	biolink:NamedThing	positive regulation of sulfur amino acid metabolic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving sulfur amino acids.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of sulfur amino acid metabolism|up-regulation of sulfur amino acid metabolic process|activation of sulfur amino acid metabolic process|up regulation of sulfur amino acid metabolic process|upregulation of sulfur amino acid metabolic process|stimulation of sulfur amino acid metabolic process													biological_process											owl:Class	
GO:0047747	biolink:NamedThing	cholate-CoA ligase activity	Catalysis of the reactions: (1) ATP + cholate + CoA = AMP + diphosphate + choloyl-CoA and (2) ATP + (25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oate + CoA = AMP + diphosphate + (25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA.	tmpzr1t_l9r_go_relaxed.owl	3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanoate-CoA synthetase activity|BAL activity|cholic acid:CoA ligase activity|3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl coenzyme A synthetase activity|choloyl-CoA synthetase activity|cholate:CoA ligase (AMP-forming)|trihydroxycoprostanoyl-CoA synthetase activity|bile acid coenzyme A ligase activity|3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanate-CoA ligase activity|3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanoate-CoA ligase activity|THCA-CoA ligase activity|3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanate:CoA ligase (AMP-forming) activity|3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanate:CoA ligase (AMP-forming)|3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoate-CoA synthetase activity|bile acid CoA ligase activity|3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanoyl coenzyme A synthetase activity|cholyl-CoA synthetase activity|choloyl coenzyme A synthetase activity|cholate thiokinase activity|cholic thiokinase activity|3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanate-CoA ligase activity|3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanate--CoA ligase activity|3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoate-CoA ligase activity				MetaCyc:CHOLATE--COA-LIGASE-RXN|EC:6.2.1.7							GO:0047477		molecular_function											owl:Class	
GO:0006278	biolink:NamedThing	RNA-dependent DNA biosynthetic process	A DNA biosynthetic process that uses RNA as a template for RNA-dependent DNA polymerases (e.g. reverse transcriptase) that synthesize the new strand.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0043375	biolink:NamedThing	CD8-positive, alpha-beta T cell lineage commitment	The process in which an immature T cell becomes committed to becoming a CD8-positive, alpha-beta T cell.	tmpzr1t_l9r_go_relaxed.owl	CD8-positive, alpha-beta T-cell lineage commitment|CD8-positive, alpha-beta T lymphocyte lineage commitment|CD8-positive, alpha-beta T-lymphocyte lineage commitment|CD8-positive, alpha-beta T cell fate commitment													biological_process											owl:Class	
GO:0060914	biolink:NamedThing	heart formation	The developmental process pertaining to the initial formation of the heart from unspecified parts. This process begins with the specific processes that contribute to the appearance of the heart field and the arrival of cardiac neural crest to the heart region. The process ends when the structural rudiment is recognizable.	tmpzr1t_l9r_go_relaxed.owl	cardiogenesis							dph	2009-09-17T09:02:13Z					biological_process											owl:Class	
GO:0000089	biolink:NamedThing	mitotic metaphase	The cell cycle phase, following prophase, during which chromosomes become aligned on the equatorial plate of the cell as part of a mitotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl						Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).								biological_process											owl:Class	
GO:0051323	biolink:NamedThing	metaphase	The cell cycle phase, following prophase or prometaphase in higher eukaryotes, during which chromosomes become aligned on the equatorial plate of the cell.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Metaphase	Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).								biological_process											owl:Class	
GO:0005213	biolink:NamedThing	structural constituent of egg chorion	The action of a molecule that contributes to the structural integrity of an egg chorion. An example of this is found in Drosophila melanogaster.	tmpzr1t_l9r_go_relaxed.owl	structural constituent of chorion|structural protein of chorion													molecular_function											owl:Class	
GO:0051022	biolink:NamedThing	Rho GDP-dissociation inhibitor binding	Binding to a Rho GDP-dissociation inhibitor protein.	tmpzr1t_l9r_go_relaxed.owl	Rho GDI binding													molecular_function											owl:Class	
GO:0051021	biolink:NamedThing	GDP-dissociation inhibitor binding	Binding to a GDP-dissociation inhibitor protein.	tmpzr1t_l9r_go_relaxed.owl	GDI binding													molecular_function											owl:Class	
GO:0047949	biolink:NamedThing	glutarate-semialdehyde dehydrogenase (NAD+) activity	Catalysis of the reaction: glutarate semialdehyde + NAD+ + H2O = glutarate + NADH.	tmpzr1t_l9r_go_relaxed.owl	glutarate semialdehyde dehydrogenase (NAD+) activity|glutarate-semialdehyde:NAD+ oxidoreductase activity				EC:1.2.1.20|MetaCyc:GLUTARATE-SEMIALDEHYDE-DEHYDROGENASE-RXN|RHEA:12064									molecular_function											owl:Class	
GO:0014876	biolink:NamedThing	response to injury involved in regulation of muscle adaptation	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a injury. This process occurs as part of the regulation of muscle adaptation.	tmpzr1t_l9r_go_relaxed.owl	response to injury involved in regulation of muscle plasticity													biological_process											owl:Class	
GO:0009611	biolink:NamedThing	response to wounding	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to the organism.	tmpzr1t_l9r_go_relaxed.owl	physiological response to wounding											GO:0002245		biological_process											owl:Class	
GO:0045861	biolink:NamedThing	negative regulation of proteolysis	Any process that stops, prevents, or reduces the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein.	tmpzr1t_l9r_go_relaxed.owl	downregulation of proteolysis|inhibition of proteolysis|down regulation of proteolysis|down-regulation of proteolysis|negative regulation of peptidolysis													biological_process											owl:Class	
GO:0035353	biolink:NamedThing	nicotinamide mononucleotide transmembrane transport	The process in which nicotinamide mononucleotide is transported across a membrane. Nicotinamide mononucleotide is a ribonucleotide in which the nitrogenous base, nicotinamide, is in beta-n-glycosidic linkage with the c-1 position of d-ribose. It is a constituent of NAD and NADP.	tmpzr1t_l9r_go_relaxed.owl	nicotinamide mononucleotide membrane transport					Note that this term is not intended for use in annotating lateral movement within membranes.		bf	2010-03-04T03:46:55Z					biological_process											owl:Class	
GO:0015890	biolink:NamedThing	nicotinamide mononucleotide transport	The directed movement of nicotinamide mononucleotide into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Nicotinamide mononucleotide is a ribonucleotide in which the nitrogenous base, nicotinamide, is in beta-n-glycosidic linkage with the c-1 position of D-ribose. It is a constituent of NAD and NADP.	tmpzr1t_l9r_go_relaxed.owl	nicotinamide ribonucleotide transport													biological_process											owl:Class	
GO:1905821	biolink:NamedThing	positive regulation of chromosome condensation	Any process that activates or increases the frequency, rate or extent of chromosome condensation.	tmpzr1t_l9r_go_relaxed.owl	up regulation of nuclear chromosome condensation|up regulation of eukaryotic chromosome condensation|up-regulation of chromosome condensation|up-regulation of eukaryotic chromosome condensation|positive regulation of nuclear chromosome condensation|upregulation of chromosome condensation|activation of eukaryotic chromosome condensation|up regulation of chromosome condensation|positive regulation of eukaryotic chromosome condensation|up-regulation of nuclear chromosome condensation|activation of chromosome condensation|activation of nuclear chromosome condensation|upregulation of eukaryotic chromosome condensation|upregulation of nuclear chromosome condensation							bhm	2017-01-13T14:13:44Z					biological_process											owl:Class	
GO:1900937	biolink:NamedThing	positive regulation of nonadec-1-ene biosynthetic process	Any process that activates or increases the frequency, rate or extent of nonadec-1-ene biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	upregulation of nonadec-1-ene formation|positive regulation of nonadec-1-ene biosynthesis|upregulation of nonadec-1-ene synthesis|activation of nonadec-1-ene biosynthetic process|activation of nonadec-1-ene formation|up regulation of nonadec-1-ene formation|up-regulation of nonadec-1-ene synthesis|upregulation of nonadec-1-ene anabolism|upregulation of nonadec-1-ene biosynthetic process|up regulation of nonadec-1-ene biosynthetic process|positive regulation of nonadec-1-ene synthesis|up-regulation of nonadec-1-ene formation|up regulation of nonadec-1-ene synthesis|up-regulation of nonadec-1-ene biosynthesis|positive regulation of nonadec-1-ene formation|up-regulation of nonadec-1-ene biosynthetic process|up-regulation of nonadec-1-ene anabolism|up regulation of nonadec-1-ene biosynthesis|up regulation of nonadec-1-ene anabolism|upregulation of nonadec-1-ene biosynthesis|activation of nonadec-1-ene anabolism|activation of nonadec-1-ene biosynthesis|positive regulation of nonadec-1-ene anabolism|activation of nonadec-1-ene synthesis							tt	2012-06-14T03:14:04Z					biological_process											owl:Class	
GO:0014003	biolink:NamedThing	oligodendrocyte development	The process aimed at the progression of an oligodendrocyte over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. An oligodendrocyte is a type of glial cell involved in myelinating the axons in the central nervous system.	tmpzr1t_l9r_go_relaxed.owl	oligodendrocyte cell development													biological_process											owl:Class	
GO:0021782	biolink:NamedThing	glial cell development	The process aimed at the progression of a glial cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0106219	biolink:NamedThing	zinc ion sensor activity	Binding to and responding, e.g. by conformational change, to changes in the cellular level of zinc.	tmpzr1t_l9r_go_relaxed.owl								hjd	2019-08-15T16:45:43Z					molecular_function											owl:Class	
GO:1904343	biolink:NamedThing	positive regulation of colon smooth muscle contraction	Any process that activates or increases the frequency, rate or extent of colon smooth muscle contraction.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of colon smooth muscle contraction|up regulation of colon smooth muscle contraction|upregulation of colon smooth muscle contraction|activation of colon smooth muscle contraction							sl	2015-06-11T21:17:11Z					biological_process											owl:Class	
GO:1901656	biolink:NamedThing	glycoside transport	The directed movement of a glycoside into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl								pr	2012-11-20T11:59:16Z					biological_process											owl:Class	
GO:0047622	biolink:NamedThing	adenosine nucleosidase activity	Catalysis of the reaction: adenosine + H2O = D-ribose + adenine.	tmpzr1t_l9r_go_relaxed.owl	N-ribosyladenine ribohydrolase activity|adenosinase activity|ANase activity|adenosine hydrolase activity|adenosine ribohydrolase activity				RHEA:18669|MetaCyc:ADENOSINE-NUCLEOSIDASE-RXN|EC:3.2.2.7									molecular_function											owl:Class	
GO:0008477	biolink:NamedThing	purine nucleosidase activity	Catalysis of the reaction: a N-D-ribosylpurine + H2O = a purine + D-ribose.	tmpzr1t_l9r_go_relaxed.owl	nucleosidase activity|IAG-NH activity|purine beta-ribosidase activity|purine ribonucleosidase activity|nucleoside hydrolase activity|ribonucleoside hydrolase activity|purine nucleoside hydrolase activity|nucleosidase g activity|purine nucleosidase reaction|N-ribosyl purine ribohydrolase activity|purine-specific nucleoside N-ribohydrolase activity|N-D-ribosylpurine ribohydrolase activity|inosine-adenosine-guanosine preferring nucleoside hydrolase activity|purine-nucleoside ribohydrolase activity|IAG-nucleoside hydrolase activity				MetaCyc:PURINE-NUCLEOSIDASE-RXN|RHEA:23344|EC:3.2.2.1									molecular_function											owl:Class	
GO:0010990	biolink:NamedThing	regulation of SMAD protein complex assembly	Any process that modulates the rate, frequency, or extent of SMAD protein complex assembly. SMAD protein complex assembly is the aggregation, arrangement and bonding together of a set of components to form a protein complex that contains SMAD proteins.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-06-03T11:28:05Z					biological_process											owl:Class	
GO:0016853	biolink:NamedThing	isomerase activity	Catalysis of the geometric or structural changes within one molecule. Isomerase is the systematic name for any enzyme of EC class 5.	tmpzr1t_l9r_go_relaxed.owl	other isomerase activity				Reactome:R-HSA-6787623|EC:5.-.-.-									molecular_function											owl:Class	
GO:0102791	biolink:NamedThing	sulfuretin synthase activity	Catalysis of the reaction: butein 4'-beta-D-glucoside + O2 + 2 H+ = sulfuretin 6-glucoside + 2 H2O.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-8008|EC:1.21.3.6									molecular_function											owl:Class	
GO:0015209	biolink:NamedThing	cytosine transmembrane transporter activity	Enables the transfer of cytosine, 4-amino-2-hydroxypyrimidine from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0005350	biolink:NamedThing	pyrimidine nucleobase transmembrane transporter activity	Enables the transfer of pyrimidine nucleobases, one of the two classes of nitrogen-containing ring compounds found in DNA and RNA, from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	pyrimidine transmembrane transporter activity|pyrimidine base transmembrane transporter activity													molecular_function											owl:Class	
GO:0070884	biolink:NamedThing	regulation of calcineurin-NFAT signaling cascade	Any process that modulates the frequency, rate or extent of the calcineurin-NFAT signaling cascade.	tmpzr1t_l9r_go_relaxed.owl	regulation of calcineurin-NFAT signalling cascade|regulation of calcineurin-NFAT signaling pathway|regulation of NFAT protein import into nucleus|NFAT protein import into nucleus							mah	2009-08-26T03:25:30Z			GO:0051531|GO:0051532		biological_process											owl:Class	
GO:0099638	biolink:NamedThing	endosome to plasma membrane protein transport	The directed movement of proteins from the endosome to the plasma membrane in transport vesicles.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0010734	biolink:NamedThing	negative regulation of protein glutathionylation	Any process that decreases the rate, frequency, or extent of protein glutathionylation. Protein glutathionylation is the protein modification process in which a glutathione molecule is added to a protein amino acid through a disulfide linkage.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of protein amino acid glutathionylation													biological_process											owl:Class	
GO:0045844	biolink:NamedThing	positive regulation of striated muscle tissue development	Any process that activates or increases the frequency, rate or extent of striated muscle development.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of striated muscle development|up regulation of striated muscle development|upregulation of striated muscle development|stimulation of striated muscle development|activation of striated muscle development													biological_process											owl:Class	
GO:0016202	biolink:NamedThing	regulation of striated muscle tissue development	Any process that modulates the frequency, rate or extent of striated muscle development.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1903271	biolink:NamedThing	negative regulation of cytoplasmic translational elongation through polyproline stretches	Any process that stops, prevents or reduces the frequency, rate or extent of cytoplasmic translational elongation through polyproline stretches.	tmpzr1t_l9r_go_relaxed.owl	down regulation of cytoplasmic translational elongation through polyproline stretches|downregulation of cytoplasmic translational elongation through polyproline stretches|down-regulation of cytoplasmic translational elongation through polyproline stretches|inhibition of cytoplasmic translational elongation through polyproline stretches							mcc	2014-08-08T14:54:08Z					biological_process											owl:Class	
GO:1903270	biolink:NamedThing	regulation of cytoplasmic translational elongation through polyproline stretches	Any process that modulates the frequency, rate or extent of cytoplasmic translational elongation through polyproline stretches.	tmpzr1t_l9r_go_relaxed.owl								mcc	2014-08-08T14:53:59Z					biological_process											owl:Class	
GO:0021680	biolink:NamedThing	cerebellar Purkinje cell layer development	The process whose specific outcome is the progression of the cerebellar Purkinje cell layer over time, from its formation to the mature structure. The Purkinje cell layer lies just underneath the molecular layer of the cerebellar cortex. It contains the neuronal cell bodies of the Purkinje cells that are arranged side by side in a single layer. Candelabrum interneurons are vertically oriented between the Purkinje cells. Purkinje neurons are inhibitory and provide the output of the cerebellar cortex through axons that project into the white matter. Extensive dendritic trees from the Purkinje cells extend upward in a single plane into the molecular layer where they synapse with parallel fibers of granule cells.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0002638	biolink:NamedThing	negative regulation of immunoglobulin production	Any process that stops, prevents, or reduces the frequency, rate, or extent of immunoglobulin production.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of immunoglobulin production|negative regulation of immunoglobulin biosynthetic process|negative regulation of immunoglobulin secretion|downregulation of immunoglobulin production|down regulation of immunoglobulin production|inhibition of immunoglobulin production											GO:0051025|GO:0002641		biological_process											owl:Class	
GO:1900244	biolink:NamedThing	positive regulation of synaptic vesicle endocytosis	Any process that activates or increases the frequency, rate or extent of synaptic vesicle endocytosis.	tmpzr1t_l9r_go_relaxed.owl	upregulation of synaptic vesicle retrieval|up-regulation of synaptic vesicle retrieval|up regulation of synaptic vesicle retrieval|upregulation of synaptic vesicle endocytosis|positive regulation of synaptic vesicle retrieval|activation of synaptic vesicle endocytosis|up-regulation of synaptic vesicle endocytosis|up regulation of synaptic vesicle endocytosis|activation of synaptic vesicle retrieval							rl	2012-03-28T01:40:44Z					biological_process											owl:Class	
GO:0050745	biolink:NamedThing	peptide cross-linking via L-cysteinyl-5-imidazolinone glycine	The formation of a protein active site cross-link from the alpha-carboxyl carbon of residue N, a cysteine, to the alpha-amino nitrogen of residue N+2, a glycine, coupled with the formation of a double bond to the alpha-amino nitrogen of residue N+1 which loses one hydrogen, and the loss of a molecule of water.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0188									biological_process											owl:Class	
GO:0004016	biolink:NamedThing	adenylate cyclase activity	Catalysis of the reaction: ATP = 3',5'-cyclic AMP + diphosphate.	tmpzr1t_l9r_go_relaxed.owl	adenylylcyclase activity|3',5'-cyclic AMP synthetase activity|ATP diphosphate-lyase (cyclizing) activity|ATP diphosphate-lyase (cyclizing; 3',5'-cyclic-AMP-forming) activity|adenyl cyclase activity|cAMP generating peptide activity|adenylyl cyclase activity|ATP pyrophosphate-lyase activity				Reactome:R-HSA-5610727|Reactome:R-HSA-5211224|RHEA:15389|MetaCyc:ADENYLATECYC-RXN|Reactome:R-HSA-392129|Reactome:R-HSA-164377|EC:4.6.1.1|Reactome:R-HSA-170676|Reactome:R-HSA-381607									molecular_function											owl:Class	
GO:1904624	biolink:NamedThing	regulation of glycine secretion, neurotransmission	Any process that modulates the frequency, rate or extent of glycine secretion, neurotransmission.	tmpzr1t_l9r_go_relaxed.owl								hjd	2015-08-27T20:03:38Z					biological_process											owl:Class	
GO:0051955	biolink:NamedThing	regulation of amino acid transport	Any process that modulates the frequency, rate or extent of the directed movement of amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0010981	biolink:NamedThing	regulation of cell wall macromolecule metabolic process	Any process that modulates the rate, frequency or extent of cell wall macromolecule metabolism. Cell wall macromolecule metabolic processes are the chemical reactions and pathways involving macromolecules forming, or destined to form, part of the cell wall. A cell wall is a rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells, maintaining their shape and protecting them from osmotic lysis.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-06-01T11:55:35Z					biological_process											owl:Class	
GO:0071285	biolink:NamedThing	cellular response to lithium ion	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lithium (Li+) ion stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-12-10T04:04:13Z					biological_process											owl:Class	
GO:0044085	biolink:NamedThing	cellular component biogenesis	A process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cellular component. Includes biosynthesis of constituent macromolecules, and those macromolecular modifications that are involved in synthesis or assembly of the cellular component.	tmpzr1t_l9r_go_relaxed.owl	cellular component biogenesis at cellular level											GO:0071843		biological_process											owl:Class	
GO:0071522	biolink:NamedThing	ureidoglycine aminohydrolase activity	Catalysis of the reaction: ureidoglycine + H2O = S-ureidoglycolate + NH3.	tmpzr1t_l9r_go_relaxed.owl					EC:3.5.3.26|RHEA:25241|MetaCyc:URUR-RXN			mah	2010-01-07T01:43:58Z					molecular_function											owl:Class	
GO:0035763	biolink:NamedThing	dorsal motor nucleus of vagus nerve structural organization	The process that contributes to the act of creating the structural organization of the dorsal motor nucleus of the vagus nerve. This process pertains to the physical shaping of a rudimentary structure.	tmpzr1t_l9r_go_relaxed.owl	dorsal motor nucleus of vagus nerve structural organisation							bf	2011-03-29T02:47:56Z					biological_process											owl:Class	
GO:0099104	biolink:NamedThing	potassium channel activator activity	Binds to and increases the activity of a potassium channel, resulting in its opening.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0140677	biolink:NamedThing	molecular function activator activity	A molecular function regulator that activates or increases the activity of its target via non-covalent binding that does not result in covalent modification to the target.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/21782						pg	2021-07-07T07:24:16Z					molecular_function											owl:Class	
GO:0099161	biolink:NamedThing	regulation of presynaptic dense core granule exocytosis	Any process that modulates the frequency, rate or extent of presynaptic dense core granule exocytosis.	tmpzr1t_l9r_go_relaxed.owl	regulation of presynaptic dense core vesicle exocytosis							dos	2017-09-10T10:59:08Z					biological_process											owl:Class	
GO:0046153	biolink:NamedThing	ommochrome catabolic process	The chemical reactions and pathways resulting in the breakdown of ommochromes, any of a large group of natural polycyclic pigments commonly found in the Arthropoda, particularly in the ommatidia of the compound eye.	tmpzr1t_l9r_go_relaxed.owl	ommochrome catabolism|ommochrome degradation|ommochrome breakdown													biological_process											owl:Class	
GO:0097631	biolink:NamedThing	integral component of omegasome membrane	The component of the omegasome membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.	tmpzr1t_l9r_go_relaxed.owl	omegasome integral membrane protein|integral to omegasome membrane													cellular_component											owl:Class	
GO:0047312	biolink:NamedThing	L-phenylalanine:pyruvate aminotransferase activity	Catalysis of the reaction: pyruvate + L-phenylalanine = phenylpyruvate + L-alanine.	tmpzr1t_l9r_go_relaxed.owl	phenylalanine (histidine) aminotransferase activity|phenylalanine(histidine):pyruvate aminotransferase activity|phenylalanine(histidine) transaminase activity|histidine aminotransferase activity|L-phenylalanine:pyruvate transaminase activity|phenylalanine(histidine) aminotransferase activity|L-phenylalanine(L-histidine):pyruvate aminotransferase activity|L-histidine:pyruvate aminotransferase activity|histidine:pyruvate aminotransferase activity				Reactome:R-HSA-893593|RHEA:13053|EC:2.6.1.58|MetaCyc:2.6.1.58-RXN|KEGG_REACTION:R00692									molecular_function											owl:Class	
GO:0031227	biolink:NamedThing	intrinsic component of endoplasmic reticulum membrane	The component of the endoplasmic reticulum membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.	tmpzr1t_l9r_go_relaxed.owl	intrinsic to endoplasmic reticulum membrane													cellular_component											owl:Class	
GO:0043999	biolink:NamedThing	histone acetyltransferase activity (H2A-K5 specific)	Catalysis of the reaction: acetyl-CoA + histone H2A L-lysine (position 5) = CoA + histone H2A N6-acetyl-L-lysine (position 5).	tmpzr1t_l9r_go_relaxed.owl	histone lysine N-acetyltransferase activity (H2A-K5 specific)													molecular_function											owl:Class	
GO:0043998	biolink:NamedThing	H2A histone acetyltransferase activity	Catalysis of the reaction: acetyl-CoA + histone H2A L-lysine = CoA + histone H2A N6-acetyl-L-lysine.	tmpzr1t_l9r_go_relaxed.owl	H2A histone lysine N-acetyltransferase activity													molecular_function											owl:Class	
GO:0016642	biolink:NamedThing	oxidoreductase activity, acting on the CH-NH2 group of donors, disulfide as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH2 group acts as a hydrogen or electron donor and reduces a disulfide group.	tmpzr1t_l9r_go_relaxed.owl	oxidoreductase activity, acting on the CH-NH2 group of donors, disulphide as acceptor				EC:1.4.4.-									molecular_function											owl:Class	
GO:0016638	biolink:NamedThing	oxidoreductase activity, acting on the CH-NH2 group of donors	Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH2 group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.	tmpzr1t_l9r_go_relaxed.owl	oxidoreductase activity, acting on the CH-NH2 group of donors, other acceptors				EC:1.4.-.-									molecular_function											owl:Class	
GO:2000601	biolink:NamedThing	positive regulation of Arp2/3 complex-mediated actin nucleation	Any process that activates or increases the frequency, rate or extent of Arp2/3 complex-mediated actin nucleation.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of branched actin filament nucleation|positive regulation of actin filament branch nucleation							bf	2011-04-14T12:35:44Z					biological_process											owl:Class	
GO:0021931	biolink:NamedThing	rostral hindbrain neuronal precursor cell proliferation	The multiplication or reproduction of neuroblasts that will give rise to neurons of the lateral pontine nucleus and the locus ceruleus.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0021924	biolink:NamedThing	cell proliferation in external granule layer	The multiplication or reproduction of neuroblasts resulting in the expansion of a cell population in the external granule layer of the hindbrain. The external granule layer is the layer that originates from the rostral half of the rhombic lip in the first rhombomere.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0060743	biolink:NamedThing	epithelial cell maturation involved in prostate gland development	The developmental process, independent of morphogenetic (shape) change, that is required for an epithelial cell of the prostate gland to attain its fully functional state. An epithelial cell is a cell usually found in a two-dimensional sheet with a free surface.	tmpzr1t_l9r_go_relaxed.owl	prostate gland epithelial cell development							dph	2009-06-16T09:34:42Z					biological_process											owl:Class	
GO:0002070	biolink:NamedThing	epithelial cell maturation	The developmental process, independent of morphogenetic (shape) change, that is required for an epithelial cell to attain its fully functional state. An epithelial cell is a cell usually found in a two-dimensional sheet with a free surface.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0018282	biolink:NamedThing	metal incorporation into metallo-sulfur cluster	The formation of a cluster of several metal atoms, including iron, nickel, molybdenum, vanadium, or copper, with one or more bridging (mu-bond) sulfur atoms; amino acids residues in proteins that may ligate the metal sulfur cluster are cysteine, histidine, aspartate, glutamate, serine and cysteine persulfide.	tmpzr1t_l9r_go_relaxed.owl	metal incorporation into metallo-sulphur cluster													biological_process											owl:Class	
GO:0061092	biolink:NamedThing	positive regulation of phospholipid translocation	Any process that increases the frequency, rate or extent of the translocation, or flipping, of phospholipid molecules from one monolayer of a membrane bilayer to the opposite monolayer.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-04-26T01:54:22Z					biological_process											owl:Class	
GO:2001140	biolink:NamedThing	positive regulation of phospholipid transport	Any process that activates or increases the frequency, rate or extent of phospholipid transport.	tmpzr1t_l9r_go_relaxed.owl								kmv	2011-10-14T06:16:14Z					biological_process											owl:Class	
GO:0048819	biolink:NamedThing	regulation of hair follicle maturation	Any process that modulates the frequency, rate or extent of hair follicle maturation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0043011	biolink:NamedThing	myeloid dendritic cell differentiation	The process in which a monocyte acquires the specialized features of a dendritic cell, an immunocompetent cell of the lymphoid and hemopoietic systems and skin.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Dendritic_cell									biological_process											owl:Class	
GO:0097028	biolink:NamedThing	dendritic cell differentiation	The process in which a precursor cell type acquires the specialized features of a dendritic cell. A dendritic cell is a leukocyte of dendritic lineage specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation.	tmpzr1t_l9r_go_relaxed.owl						Note that immunologists typically use the word 'maturation' to refer to dendritic cells undergoing the process that GO describes as 'cell differentiation'.		pr	2011-04-01T10:08:42Z					biological_process											owl:Class	
GO:0001566	biolink:NamedThing	non-kinase phorbol ester receptor activity	Combining with a phorbol ester and transmitting the signal by a mechanism independent of kinase activity.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0001565	biolink:NamedThing	phorbol ester receptor activity	Combining with a phorbol ester and transmitting the signal to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0019687	biolink:NamedThing	pyruvate biosynthetic process from acetate	The chemical reactions and pathways resulting in the formation of pyruvate from other compounds, including acetate.	tmpzr1t_l9r_go_relaxed.owl	pyruvate synthesis from acetate|pyruvate formation from acetate|pyruvate anabolism from acetate													biological_process											owl:Class	
GO:0042866	biolink:NamedThing	pyruvate biosynthetic process	The chemical reactions and pathways resulting in the formation of pyruvate, 2-oxopropanoate.	tmpzr1t_l9r_go_relaxed.owl	pyruvate biosynthesis|pyruvate synthesis|pyruvate anabolism|pyruvate formation													biological_process											owl:Class	
GO:1902254	biolink:NamedThing	negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator	Any process that stops, prevents or reduces the frequency, rate or extent of intrinsic apoptotic signaling pathway by p53 class mediator.	tmpzr1t_l9r_go_relaxed.owl	inhibition of signal transduction by p53 class mediator resulting in induction of apoptosis|down regulation of signal transduction by p53 class mediator resulting in induction of apoptosis|negative regulation of signal transduction by p53 class mediator resulting in induction of apoptosis|inhibition of intrinsic apoptotic signaling pathway by p53 class mediator|negative regulation of intrinsic apoptotic signaling pathway by signal transduction by p53 class mediator|down-regulation of signal transduction by p53 class mediator resulting in induction of apoptosis|downregulation of intrinsic apoptotic signaling pathway by p53 class mediator|down-regulation of intrinsic apoptotic signaling pathway by signal transduction by p53 class mediator|down regulation of intrinsic apoptotic signaling pathway by signal transduction by p53 class mediator|down-regulation of intrinsic apoptotic signaling pathway by p53 class mediator|inhibition of intrinsic apoptotic signaling pathway by signal transduction by p53 class mediator|down regulation of intrinsic apoptotic signaling pathway by p53 class mediator|downregulation of signal transduction by p53 class mediator resulting in induction of apoptosis|downregulation of intrinsic apoptotic signaling pathway by signal transduction by p53 class mediator							rl	2013-06-20T19:41:43Z					biological_process											owl:Class	
GO:1901797	biolink:NamedThing	negative regulation of signal transduction by p53 class mediator	Any process that stops, prevents or reduces the frequency, rate or extent of signal transduction by p53 class mediator.	tmpzr1t_l9r_go_relaxed.owl	downregulation of signal transduction by p53 class mediator|down regulation of signal transduction by p53 class mediator|inhibition of signal transduction by p53 class mediator|down-regulation of signal transduction by p53 class mediator							hjd	2013-01-18T21:51:44Z					biological_process											owl:Class	
GO:0032742	biolink:NamedThing	positive regulation of interleukin-19 production	Any process that activates or increases the frequency, rate, or extent of interleukin-19 production.	tmpzr1t_l9r_go_relaxed.owl	upregulation of interleukin-19 production|activation of interleukin-19 production|up regulation of interleukin-19 production|stimulation of interleukin-19 production|positive regulation of interleukin-19 biosynthetic process|up-regulation of interleukin-19 production|positive regulation of IL-19 production											GO:0045386		biological_process											owl:Class	
GO:0061988	biolink:NamedThing	karyosome formation	The chromosome organization process in which meiotic chromosomes in the germ cell nucleus cluster together to form a compact spherical structure called the karyosome.	tmpzr1t_l9r_go_relaxed.owl								dph	2018-02-15T21:24:08Z					biological_process											owl:Class	
GO:0042381	biolink:NamedThing	hemolymph coagulation	Any process in which factors in the hemolymph (the invertebrate equivalent of vertebrate blood and lymph) precipitate into insoluble clots in order to prevent loss of body fluid, and at the same time prevent the movement of microbes. Hemolymph coagulation is also part of the invertebrate humoral immune response.	tmpzr1t_l9r_go_relaxed.owl	hemolymph clotting													biological_process											owl:Class	
GO:0044075	biolink:NamedThing	modulation by symbiont of host vacuole organization	Any process in which a symbiont organism modulates the frequency, rate or extent of vacuole organization in its host organism.	tmpzr1t_l9r_go_relaxed.owl	modulation by symbiont of host vacuole organisation|modulation by symbiont of host vacuole biogenesis|regulation by symbiont of host vacuole organization|modulation of host vacuole organization by symbiont													biological_process											owl:Class	
GO:0044088	biolink:NamedThing	regulation of vacuole organization	Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a vacuole.	tmpzr1t_l9r_go_relaxed.owl	regulation of vacuole biogenesis|regulation of vacuole organisation													biological_process											owl:Class	
GO:2000138	biolink:NamedThing	positive regulation of cell proliferation involved in heart morphogenesis	Any process that activates or increases the frequency, rate or extent of cell proliferation involved in heart morphogenesis.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-09-29T12:43:57Z					biological_process											owl:Class	
GO:0050961	biolink:NamedThing	detection of temperature stimulus involved in sensory perception	The series of events in which a temperature stimulus is received and converted into a molecular signal as part of sensory perception.	tmpzr1t_l9r_go_relaxed.owl	sensory transduction of temperature stimulus|sensory perception, sensory transduction of thermal stimulus|sensory perception, sensory detection of thermal stimulus|sensory detection of heat stimulus during sensory perception|sensory transduction of thermal stimulus during sensory perception|sensory transduction of temperature stimulus during sensory perception|sensory detection of temperature stimulus|sensory detection of thermal stimulus during sensory perception|sensory perception, sensory transduction of temperature stimulus|sensory perception, sensory detection of temperature stimulus|sensory transduction of heat stimulus during sensory perception|sensory perception, sensory detection of heat stimulus|sensory detection of temperature stimulus during sensory perception|sensory perception, sensory transduction of heat stimulus													biological_process											owl:Class	
GO:0045936	biolink:NamedThing	negative regulation of phosphate metabolic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving phosphates.	tmpzr1t_l9r_go_relaxed.owl	down regulation of phosphate metabolic process|inhibition of phosphate metabolic process|negative regulation of phosphate metabolism|downregulation of phosphate metabolic process|down-regulation of phosphate metabolic process													biological_process											owl:Class	
GO:0019220	biolink:NamedThing	regulation of phosphate metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving phosphates.	tmpzr1t_l9r_go_relaxed.owl	regulation of phosphate metabolism													biological_process											owl:Class	
GO:0033478	biolink:NamedThing	UDP-rhamnose metabolic process	The chemical reactions and pathways involving UDP-L-rhamnose, a substance composed of rhamnose in glycosidic linkage with uridine diphosphate.	tmpzr1t_l9r_go_relaxed.owl	UDP-rhamnose metabolism				MetaCyc:PWY-3261									biological_process											owl:Class	
GO:0072725	biolink:NamedThing	cellular response to 4-nitroquinoline N-oxide	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 4-nitroquinoline N-oxide stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2012-05-31T11:00:42Z					biological_process											owl:Class	
GO:0045550	biolink:NamedThing	geranylgeranyl reductase activity	Catalysis of the formation of phytyl group from the stepwise reduction of a geranylgeranyl group.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0036197	biolink:NamedThing	zymosterol biosynthetic process	The chemical reactions and pathways resulting in the formation of zymosterol, (5alpha-cholesta-8,24-dien-3beta-ol).	tmpzr1t_l9r_go_relaxed.owl	zymosterol formation|zymosterol synthesis|zymosterol biosynthesis|zymosterol anabolism				UniPathway:UPA00770|MetaCyc:PWY-6074			bf	2012-04-20T10:28:46Z					biological_process											owl:Class	
GO:0016126	biolink:NamedThing	sterol biosynthetic process	The chemical reactions and pathways resulting in the formation of sterols, steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule.	tmpzr1t_l9r_go_relaxed.owl	sterol synthesis|sterol formation|sterol anabolism|sterol biosynthesis				MetaCyc:PWY-2541									biological_process											owl:Class	
GO:0071602	biolink:NamedThing	phytosphingosine biosynthetic process	The chemical reactions and pathways resulting in the formation of phytosphingosine, (2S,3S,4R)-2-aminooctadecane-1,3,4-triol.	tmpzr1t_l9r_go_relaxed.owl	phytosphingosine formation|phytosphingosine biosynthesis|phytosphingosine anabolism|phytosphingosine synthesis							mah	2010-02-04T05:15:59Z					biological_process											owl:Class	
GO:0006671	biolink:NamedThing	phytosphingosine metabolic process	The chemical reactions and pathways involving phytosphingosine, (2S,3S,4R)-2-aminooctadecane-1,3,4-triol, a constituent of many plant sphingolipids.	tmpzr1t_l9r_go_relaxed.owl	phytosphingosine metabolism													biological_process											owl:Class	
GO:0031084	biolink:NamedThing	BLOC-2 complex	A protein complex required for the biogenesis of specialized organelles of the endosomal-lysosomal system, such as melanosomes and platelet dense granules. The human complex contains the Hps3, Hps5, and Hps6 proteins; the mouse complex contains ru2 and ru.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0031082	biolink:NamedThing	BLOC complex	Any of several protein complexes required for the biogenesis of specialized organelles of the endosomal-lysosomal system, such as melanosomes, platelet dense granules, and other related organelles; acronym for biogenesis of lysosomal-related organelles complex.	tmpzr1t_l9r_go_relaxed.owl	BLOC-1 related complex													cellular_component											owl:Class	
GO:2000545	biolink:NamedThing	negative regulation of endothelial cell chemotaxis to fibroblast growth factor	Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell chemotaxis to fibroblast growth factor.	tmpzr1t_l9r_go_relaxed.owl								ebc	2011-04-03T07:14:11Z					biological_process											owl:Class	
GO:0071262	biolink:NamedThing	regulation of translational initiation in response to starvation	Any process that modulates the frequency, rate or extent of translation initiation, as a result of deprivation of nourishment.	tmpzr1t_l9r_go_relaxed.owl	regulation of translational initiation in response to nutrient starvation							mah	2009-12-08T05:31:05Z					biological_process											owl:Class	
GO:0043558	biolink:NamedThing	regulation of translational initiation in response to stress	Any process that modulates the frequency, rate or extent of translation initiation, as a result of a stimulus indicating the organism is under stress.	tmpzr1t_l9r_go_relaxed.owl	regulation of translation initiation in response to stress													biological_process											owl:Class	
GO:0032737	biolink:NamedThing	positive regulation of interleukin-14 production	Any process that activates or increases the frequency, rate, or extent of interleukin-14 production.	tmpzr1t_l9r_go_relaxed.owl	stimulation of interleukin-14 production|activation of interleukin-14 production|up regulation of interleukin-14 production|upregulation of interleukin-14 production|up-regulation of interleukin-14 production|positive regulation of interleukin-14 biosynthetic process|positive regulation of IL-14 production											GO:0045371		biological_process											owl:Class	
GO:0006391	biolink:NamedThing	transcription initiation from mitochondrial promoter	A transcription initiation process that takes place at a promoter on the mitochondrial chromosome, and results in RNA synthesis by a mitochondrial RNA polymerase.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0000959	biolink:NamedThing	mitochondrial RNA metabolic process	The chemical reactions and pathways involving RNA transcribed from the mitochondrial genome and occurring in the mitochondrion.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0005432	biolink:NamedThing	calcium:sodium antiporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Ca2+(in) + Na+(out) = Ca2+(out) + Na+(in).	tmpzr1t_l9r_go_relaxed.owl	sodium/calcium exchanger|sodium:calcium exchange|mitochondrial sodium/calcium ion exchange				Reactome:R-HSA-8949688|Reactome:R-HSA-425661|Reactome:R-HSA-8949703|RHEA:29255									molecular_function											owl:Class	
GO:0008664	biolink:NamedThing	2'-5'-RNA ligase activity	Catalysis of the formation of a phosphodiester bond between the 2'-hydroxyl group at the end of one DNA chain and the 5'-phosphate group at the end of another.	tmpzr1t_l9r_go_relaxed.owl	2'-5' RNA ligase activity													molecular_function											owl:Class	
GO:0008452	biolink:NamedThing	RNA ligase activity	Catalysis of the formation of a phosphodiester bond between a hydroxyl group at the end of one RNA chain and the 5'-phosphate group at the end of another.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0035983	biolink:NamedThing	response to trichostatin A	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a trichostatin A stimulus.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-08-23T01:48:01Z					biological_process											owl:Class	
GO:0048640	biolink:NamedThing	negative regulation of developmental growth	Any process that stops, prevents, or reduces the frequency, rate or extent of developmental growth.	tmpzr1t_l9r_go_relaxed.owl	inhibition of developmental growth|down regulation of developmental growth|down-regulation of developmental growth|downregulation of developmental growth													biological_process											owl:Class	
GO:0015916	biolink:NamedThing	fatty-acyl-CoA transport	The directed movement of fatty acyl coenzyme A into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Fatty acyl coenzyme A is an acyl group linked to 3'-phosphoadenosine-(5')diphospho(4')pantatheine (coenzyme A).	tmpzr1t_l9r_go_relaxed.owl	fatty acyl-CoA transport|fatty acyl coenzyme A transport|fatty acyl CoA transport													biological_process											owl:Class	
GO:0015868	biolink:NamedThing	purine ribonucleotide transport	The directed movement of a purine ribonucleotide, any compound consisting of a purine ribonucleoside (a purine organic base attached to a ribose sugar) esterified with (ortho)phosphate, into, out of or within a cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0052838	biolink:NamedThing	thiazole metabolic process	The chemical reactions and pathways involving thiazole, a five-membered heterocyclic ring structure containing a sulfur in the 1-position and a nitrogen in the 3-position.	tmpzr1t_l9r_go_relaxed.owl	thiazole metabolism							ai	2011-11-29T03:35:50Z					biological_process											owl:Class	
GO:0030256	biolink:NamedThing	type I protein secretion system complex	A complex of three secretory proteins that carry out secretion in the type I secretion system: an inner membrane transport ATPase (termed ABC protein for ATP-binding cassette), which provides the energy for protein secretion; an outer membrane protein, which is exported via the sec pathway; and a membrane fusion protein, which is anchored in the inner membrane and spans the periplasmic space.	tmpzr1t_l9r_go_relaxed.owl	ABC translocator complex													cellular_component											owl:Class	
GO:1901546	biolink:NamedThing	regulation of synaptic vesicle lumen acidification	Any process that modulates the frequency, rate or extent of synaptic vesicle lumen acidification.	tmpzr1t_l9r_go_relaxed.owl	regulation of synaptic vesicle lumen proton loading|regulation of synaptic vesicle lumen pH reduction							dsf	2012-10-26T16:09:24Z					biological_process											owl:Class	
GO:1903900	biolink:NamedThing	regulation of viral life cycle	Any process that modulates the frequency, rate or extent of viral life cycle.	tmpzr1t_l9r_go_relaxed.owl	regulation of viral replication|regulation of viral infectious cycle|regulation of viral assembly, maturation, egress, and release|regulation of lytic viral life cycle							pga	2015-02-09T10:22:07Z					biological_process											owl:Class	
GO:1904033	biolink:NamedThing	negative regulation of t-SNARE clustering	Any process that stops, prevents or reduces the frequency, rate or extent of t-SNARE clustering.	tmpzr1t_l9r_go_relaxed.owl	down regulation of t-SNARE clustering|downregulation of t-SNARE clustering|inhibition of t-SNARE clustering|down-regulation of t-SNARE clustering							sl	2015-03-13T21:21:44Z					biological_process											owl:Class	
GO:0051606	biolink:NamedThing	detection of stimulus	The series of events in which a stimulus is received by a cell or organism and converted into a molecular signal.	tmpzr1t_l9r_go_relaxed.owl	stimulus detection|perception of stimulus|stimulus sensing													biological_process											owl:Class	
GO:0030931	biolink:NamedThing	heterotetrameric ADPG pyrophosphorylase complex	A protein complex composed of four different subunits that possesses ADPG pyrophosphorylase activity. An example of this process is found in Mus musculus.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0030929	biolink:NamedThing	ADPG pyrophosphorylase complex	Complex that possesses ADPG pyrophosphorylase activity. In all organisms where it has been found, the complex is a tetramer. In bacteria, it is a homotetramer. In plants, the complex is a heterotetramer composed small and large subunits.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0031554	biolink:NamedThing	regulation of DNA-templated transcription, termination	Any process that modulates the frequency, rate, extent, or location of DNA-templated transcription termination, the process in which transcription is completed; the formation of phosphodiester bonds ceases, the RNA-DNA hybrid dissociates, and RNA polymerase releases the DNA.	tmpzr1t_l9r_go_relaxed.owl	transcription antiterminator activity|regulation of transcription termination, DNA-dependent|regulation of DNA-dependent transcription, termination|regulation of termination of DNA-dependent transcription													biological_process											owl:Class	
GO:0002289	biolink:NamedThing	NK T cell proliferation involved in immune response	The expansion of a NK T cell population by cell division as part of an immune response.	tmpzr1t_l9r_go_relaxed.owl	NK T lymphocyte proliferation during immune response|NK T-lymphocyte proliferation during immune response|NK T cell proliferation during immune response|natural killer T-cell proliferation during immune response|natural killer T lymphocyte proliferation during immune response|natural killer T-lymphocyte proliferation during immune response|NK T-cell proliferation during immune response													biological_process											owl:Class	
GO:0002288	biolink:NamedThing	NK T cell activation involved in immune response	The change in morphology and behavior of a mature or immature natural killer T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific, leading to the initiation or perpetuation of an immune response.	tmpzr1t_l9r_go_relaxed.owl	NK T cell activation during immune response|natural killer T lymphocyte activation during immune response|NK T-cell activation during immune response|NK T-lymphocyte activation during immune response|natural killer T-cell activation during immune response|natural killer T-lymphocyte activation during immune response|NK T lymphocyte activation during immune response													biological_process											owl:Class	
GO:0042909	biolink:NamedThing	acridine transport	The directed movement of acridine (10-azaanthracene), a heterocyclic ring compound found in crude coal-tar anthracene, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1902360	biolink:NamedThing	conversion of ds siRNA to ss siRNA involved in gene silencing by small RNA	Any conversion of ds siRNA to ss siRNA that is involved in gene silencing by small RNA.	tmpzr1t_l9r_go_relaxed.owl	conversion of double-stranded small interfering RNA to single-stranded small interfering RNA involved in RNAi-like chromatin silencing|conversion of double-stranded small interfering RNA to single-stranded small interfering RNA involved in RNA interference-like chromatin silencing|conversion of ds siRNA to ss siRNA involved in small RNA-mediated heterochromatic silencing|conversion of ds siRNA to ss siRNA involved in RNA interference-like chromatin silencing|conversion of double-stranded small interfering RNA to single-stranded small interfering RNA involved in RNA-mediated transcriptional silencing|conversion of double-stranded small interfering RNA to single-stranded small interfering RNA involved in RNAi-directed chromatin silencing|conversion of ds siRNA to ss siRNA involved in RNAi-directed chromatin silencing|conversion of ds siRNA to ss siRNA involved in chromatin silencing by small RNA|conversion of ds siRNA to ss siRNA involved in RNA-mediated chromatin silencing|conversion of double-stranded small interfering RNA to single-stranded small interfering RNA involved in chromatin silencing by small RNA|conversion of double-stranded small interfering RNA to single-stranded small interfering RNA involved in small RNA-mediated heterochromatic silencing|conversion of ds siRNA to ss siRNA involved in RNAi-like chromatin silencing|conversion of ds siRNA to ss siRNA involved in RNA-mediated transcriptional silencing|conversion of double-stranded small interfering RNA to single-stranded small interfering RNA involved in RNA-mediated chromatin silencing	https://github.com/geneontology/go-ontology/issues/22058						bf	2013-08-15T10:06:18Z					biological_process											owl:Class	
GO:0036404	biolink:NamedThing	conversion of ds siRNA to ss siRNA	The process in which double-stranded small interfering RNA (ds siRNA) molecules are converted to single-stranded small interfering RNA (ss siRNA).	tmpzr1t_l9r_go_relaxed.owl	conversion of double-stranded small interfering RNA to single-stranded small interfering RNA							bf	2013-08-14T14:24:19Z					biological_process											owl:Class	
GO:0018213	biolink:NamedThing	peptidyl-valine modification	The modification of peptidyl-valine.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0010696	biolink:NamedThing	positive regulation of mitotic spindle pole body separation	Any process that increases the rate, frequency or extent of the process involving the release of duplicated mitotic spindle pole bodies (SPBs) and their migration away from each other within the nuclear membrane.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of SPB separation													biological_process											owl:Class	
GO:0035339	biolink:NamedThing	SPOTS complex	A multiprotein complex at least composed of serine palmitoyltransferases and ORM proteins (known as ORMDL proteins in mammals and other higher vertebrates) that plays a key role in sphingolipid homeostasis.	tmpzr1t_l9r_go_relaxed.owl	serine palmitoyltransferase, Orm1/2, Tsc3 and Sac1 complex							bf	2010-03-03T10:28:42Z					cellular_component											owl:Class	
GO:0017059	biolink:NamedThing	serine C-palmitoyltransferase complex	An enzyme complex that catalyzes the transfer of a palmitoyl on to serine, forming 3-dehydro-D-sphinganine.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:1901508	biolink:NamedThing	positive regulation of acylglycerol transport	Any process that activates or increases the frequency, rate or extent of acylglycerol transport.	tmpzr1t_l9r_go_relaxed.owl	activation of acylglycerol transport|up regulation of acylglycerol transport|positive regulation of glyceride transport|up-regulation of glyceride transport|upregulation of acylglycerol transport|up-regulation of acylglycerol transport|up regulation of glyceride transport|activation of glyceride transport|upregulation of glyceride transport							sart	2012-10-17T11:06:23Z					biological_process											owl:Class	
GO:1901506	biolink:NamedThing	regulation of acylglycerol transport	Any process that modulates the frequency, rate or extent of acylglycerol transport.	tmpzr1t_l9r_go_relaxed.owl	regulation of glyceride transport							sart	2012-10-17T11:06:10Z					biological_process											owl:Class	
GO:0001832	biolink:NamedThing	blastocyst growth	An increase in size of a blastocyst due to expansion of the blastocoelic cavity cell shape changes and cell proliferation.	tmpzr1t_l9r_go_relaxed.owl						See also the Anatomical Dictionary for Mouse Development ontology terms 'TS4, blastocoelic cavity ; EMAP:17', 'TS5, blastocoelic cavity ; EMAP:27' and 'TS6, blastocoelic cavity ; EMAP:36'.								biological_process											owl:Class	
GO:1904102	biolink:NamedThing	cellular response to acadesine	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acadesine stimulus.	tmpzr1t_l9r_go_relaxed.owl								mr	2015-03-30T22:36:32Z					biological_process											owl:Class	
GO:0140409	biolink:NamedThing	positive regulation of mRNA alternative polyadenylation	Any process that activates or increases the frequency, rate or extent of mRNA alternative polyadenylation.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/15389						pg	2019-12-13T12:48:31Z					biological_process											owl:Class	
GO:2001042	biolink:NamedThing	negative regulation of septum digestion after cytokinesis	Any process that stops, prevents or reduces the frequency, rate or extent of the process of physically separating the septal cell wall material by enzymatic digestion, that occurs after daughter cells are separated by cytokinesis.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of cytokinetic cell separation							mcc	2011-08-30T05:16:55Z					biological_process											owl:Class	
GO:0001066	biolink:NamedThing	plastid single subunit type RNA polymerase activity	Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template that contains a single subunit type plastid RNA polymerase specific promoter to direct initiation and catalyses DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'.	tmpzr1t_l9r_go_relaxed.owl								krc	2010-10-19T03:54:57Z					molecular_function											owl:Class	
GO:0001064	biolink:NamedThing	single subunit type RNA polymerase activity	Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template that contains a single-subunit-type RNA polymerase-specific promoter to direct initiation and catalyses DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'.	tmpzr1t_l9r_go_relaxed.owl	T3/T7 type RNA polymerase activity							krc	2010-10-19T03:47:56Z					molecular_function											owl:Class	
GO:0098720	biolink:NamedThing	succinate import across plasma membrane	The directed movement of succinate from outside of a cell, across the plasma membrane and into the cytosol.	tmpzr1t_l9r_go_relaxed.owl	succinate import into cell							pr	2012-10-29T11:17:44Z			GO:0097404		biological_process											owl:Class	
GO:2000195	biolink:NamedThing	negative regulation of female gonad development	Any process that stops, prevents, or reduces the frequency, rate or extent of female gonad development.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of ovary development|negative regulation of ovarian development							yaf	2010-10-19T10:45:38Z					biological_process											owl:Class	
GO:2000194	biolink:NamedThing	regulation of female gonad development	Any process that modulates the frequency, rate or extent of female gonad development.	tmpzr1t_l9r_go_relaxed.owl	regulation of ovarian development|regulation of ovary development							yaf	2010-10-19T10:45:34Z					biological_process											owl:Class	
GO:0019252	biolink:NamedThing	starch biosynthetic process	The chemical reactions and pathways resulting in the formation of starch, the most important reserve polysaccharide in plants.	tmpzr1t_l9r_go_relaxed.owl	starch biosynthesis|starch anabolism|starch formation|starch synthesis				MetaCyc:PWY-622									biological_process											owl:Class	
GO:0005982	biolink:NamedThing	starch metabolic process	The chemical reactions and pathways involving starch, the most important reserve polysaccharide in plants. It is a glucan consisting of two components, amylose and amylopectin, which are both glucose homopolymers. Starch is synthesized as a temporary storage form of carbon and can be catabolized to produce sucrose.	tmpzr1t_l9r_go_relaxed.owl	starch metabolism													biological_process											owl:Class	
GO:0015936	biolink:NamedThing	coenzyme A metabolic process	The chemical reactions and pathways involving coenzyme A, 3'-phosphoadenosine-(5')diphospho(4')pantatheine, an acyl carrier in many acylation and acyl-transfer reactions in which the intermediate is a thiol ester.	tmpzr1t_l9r_go_relaxed.owl	CoA metabolism|coenzyme A metabolism											GO:0006763		biological_process											owl:Class	
GO:0034032	biolink:NamedThing	purine nucleoside bisphosphate metabolic process	The chemical reactions and pathways involving a purine nucleoside bisphosphate, a compound consisting of a purine base linked to a deoxyribose or ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar.	tmpzr1t_l9r_go_relaxed.owl	purine nucleoside bisphosphate metabolism													biological_process											owl:Class	
GO:0060639	biolink:NamedThing	positive regulation of salivary gland formation by mesenchymal-epithelial signaling	Any process that induces the formation of the salivary gland field by means of the secretion of a signal by a mesenchymal cell and its reception and interpretation by an epithelial cell resulting in it adopting the identity of a salivary gland bud cell.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of salivary gland formation by mesenchymal-epithelial signalling							dph	2009-05-20T04:26:43Z					biological_process											owl:Class	
GO:0110110	biolink:NamedThing	positive regulation of animal organ morphogenesis	Any process that activates or increases the frequency, rate or extent of animal organ morphogenesis.	tmpzr1t_l9r_go_relaxed.owl								kmv	2018-07-05T14:10:14Z					biological_process											owl:Class	
GO:0001780	biolink:NamedThing	neutrophil homeostasis	The process of regulating the proliferation and elimination of neutrophils such that the total number of neutrophils within a whole or part of an organism is stable over time in the absence of an outside stimulus.	tmpzr1t_l9r_go_relaxed.owl						Note that this term represents the return of neutrophil levels to stable numbers following an immune response as well as the proliferation and elimination of neutrophils required to maintain stable numbers in the absence of an outside stimulus.								biological_process											owl:Class	
GO:0002262	biolink:NamedThing	myeloid cell homeostasis	The process of regulating the proliferation and elimination of myeloid cells such that the total number of myeloid cells within a whole or part of an organism is stable over time in the absence of an outside stimulus.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0032198	biolink:NamedThing	MITE transposition	Any process involved in the transposition of miniature inverted-repeat transposable elements (MITEs).	tmpzr1t_l9r_go_relaxed.owl	Class III transposition													biological_process											owl:Class	
GO:0003324	biolink:NamedThing	pancreatic D cell development	The process whose specific outcome is the progression of a pancreatic delta cell over time, from its formation to the mature structure. A delta cell is a cell of the pancreas that produces somatostatin.	tmpzr1t_l9r_go_relaxed.owl	pancreatic delta cell development							dph	2009-11-02T08:23:26Z					biological_process											owl:Class	
GO:0004529	biolink:NamedThing	exodeoxyribonuclease activity	Catalysis of the sequential cleavage of mononucleotides from a free 5' or 3' terminus of a DNA molecule.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0004527	biolink:NamedThing	exonuclease activity	Catalysis of the hydrolysis of ester linkages within nucleic acids by removing nucleotide residues from the 3' or 5' end.	tmpzr1t_l9r_go_relaxed.owl	exonuclease IX activity											GO:0008857		molecular_function											owl:Class	
GO:0032179	biolink:NamedThing	germ tube	The slender tubular outgrowth first produced by most spores in germination.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Germ_tube									cellular_component											owl:Class	
GO:0070601	biolink:NamedThing	centromeric sister chromatid cohesion	The cell cycle process in which the sister chromatids of a replicated chromosome are joined along the length of the centromeric region of the chromosome.	tmpzr1t_l9r_go_relaxed.owl	sister chromatid cohesion at centromere							mah	2009-04-28T04:31:00Z					biological_process											owl:Class	
GO:0007062	biolink:NamedThing	sister chromatid cohesion	The cell cycle process in which the sister chromatids of a replicated chromosome become tethered to each other.	tmpzr1t_l9r_go_relaxed.owl	coheson-mediated DNA tethering|sister chromatid alignment													biological_process											owl:Class	
GO:0032041	biolink:NamedThing	NAD-dependent histone deacetylase activity (H3-K14 specific)	Catalysis of the reaction: histone H3 N6-acetyl-L-lysine (position 14) + H2O = histone H3 L-lysine (position 14) + acetate. This reaction requires the presence of NAD, and represents the removal of an acetyl group from lysine at position 14 of the histone H3 protein.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0046161	biolink:NamedThing	heme a catabolic process	The chemical reactions and pathways resulting in the breakdown of heme a, a derivative of heme found in cytochrome aa3.	tmpzr1t_l9r_go_relaxed.owl	haem a catabolic process|heme a catabolism|heme a breakdown|haem a catabolism|heme a degradation													biological_process											owl:Class	
GO:0019900	biolink:NamedThing	kinase binding	Binding to a kinase, any enzyme that catalyzes the transfer of a phosphate group.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0048201	biolink:NamedThing	vesicle targeting, plasma membrane to endosome	The process in which vesicles formed at the plasma membrane are directed to specific destinations in endosome membranes, mediated by molecules at the vesicle membrane and target membrane surfaces.	tmpzr1t_l9r_go_relaxed.owl	plasma membrane to endosome targeting													biological_process											owl:Class	
GO:0006903	biolink:NamedThing	vesicle targeting	The process in which vesicles are directed to specific destination membranes. Targeting involves coordinated interactions among cytoskeletal elements (microtubules or actin filaments), motor proteins, molecules at the vesicle membrane and target membrane surfaces, and vesicle cargo.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0050160	biolink:NamedThing	orsellinate-depside hydrolase activity	Catalysis of the reaction: H(2)O + orsellinate depside = 2 o-orsellinate + H(+).	tmpzr1t_l9r_go_relaxed.owl	lecanorate hydrolase activity				MetaCyc:ORSELLINATE-DEPSIDE-HYDROLASE-RXN|KEGG_REACTION:R00054|RHEA:19549|EC:3.1.1.40									molecular_function											owl:Class	
GO:0140043	biolink:NamedThing	lipid droplet localization to prospore membrane leading edge	Any process in which a lipid droplet is transported to, or maintained to the prospore membrane leading edge.	tmpzr1t_l9r_go_relaxed.owl	adiposome localization to FSM membrane leading edge|lipid body localization to forespore membrane leading edge|lipid body localization to ascospore-type prospore membrane leading edge|lipid particle localization to FSM membrane leading edge|adiposome localization to forespore membrane leading edge|lipid body localization to FSM membrane leading edge|lipid particle localization to forespore membrane leading edge|adiposome localization to ascospore-type prospore membrane leading edge|lipid particle localization to ascospore-type prospore membrane leading edge							pg	2017-06-19T09:20:13Z					biological_process											owl:Class	
GO:0010876	biolink:NamedThing	lipid localization	Any process in which a lipid is transported to, or maintained in, a specific location.	tmpzr1t_l9r_go_relaxed.owl	lipid localisation													biological_process											owl:Class	
GO:1901534	biolink:NamedThing	positive regulation of hematopoietic progenitor cell differentiation	Any process that activates or increases the frequency, rate or extent of hematopoietic progenitor cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of haematopoietic progenitor cell differentiation|up-regulation of haemopoietic progenitor cell differentiation|upregulation of hematopoietic progenitor cell differentiation|up regulation of hematopoietic progenitor cell differentiation|activation of hematopoietic progenitor cell differentiation|upregulation of hemopoietic progenitor cell differentiation|up-regulation of hematopoietic progenitor cell differentiation|up-regulation of haematopoietic progenitor cell differentiation|up regulation of haemopoietic progenitor cell differentiation|activation of haematopoietic progenitor cell differentiation|positive regulation of hemopoietic progenitor cell differentiation|upregulation of haematopoietic progenitor cell differentiation|activation of haemopoietic progenitor cell differentiation|up regulation of hemopoietic progenitor cell differentiation|upregulation of haemopoietic progenitor cell differentiation|up-regulation of hemopoietic progenitor cell differentiation|positive regulation of haemopoietic progenitor cell differentiation|up regulation of haematopoietic progenitor cell differentiation|activation of hemopoietic progenitor cell differentiation							vk	2012-10-24T11:23:14Z					biological_process											owl:Class	
GO:0002285	biolink:NamedThing	lymphocyte activation involved in immune response	A change in morphology and behavior of a lymphocyte resulting from exposure to a specific antigen, mitogen, cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response.	tmpzr1t_l9r_go_relaxed.owl	lymphocyte activation during immune response													biological_process											owl:Class	
GO:0046649	biolink:NamedThing	lymphocyte activation	A change in morphology and behavior of a lymphocyte resulting from exposure to a specific antigen, mitogen, cytokine, chemokine, cellular ligand, or soluble factor.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0051357	biolink:NamedThing	peptide cross-linking via 3-(2-methylthio)ethyl-6-(4-hydroxybenzylidene)-5-iminopiperazin-2-one	The formation of a 2-keto-5-iminopiperazine protein chromophore cross-link from the alpha-amino nitrogen of residue n, a methionine, to the alpha-carboxyl carbon of residue n+1, a tyrosine, and a dehydration to form a double bond to the alpha-amino nitrogen of residue n+2. This cross-linking is coupled with a dehydrogenation of residue n+1 to form a double bond between the alpha and beta carbons.	tmpzr1t_l9r_go_relaxed.owl	biosynthetic process of protein-protein cross-link via L-methionyl-L-tyrosyl-2-keto-5-iminopiperazine|biosynthesis of protein-protein cross-link via L-methionyl-L-tyrosyl-2-keto-5-iminopiperazine				RESID:AA0377	Note that this predicted modification is now thought not to exist. See the biological process term 'peptide cross-linking via 2-imino-methionine 5-imidazolinone glycine ; GO:0051359'.								biological_process											owl:Class	
GO:0072173	biolink:NamedThing	metanephric tubule morphogenesis	The process in which the anatomical structures of a metanephric tubule are generated and organized from an epithelium. A metanephric tubule is an epithelial tube that is part of the metanephros.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-02-26T02:06:42Z					biological_process											owl:Class	
GO:0098640	biolink:NamedThing	integrin binding involved in cell-matrix adhesion	Any integrin binding that occurs as part of the process of cell-matrix adhesion.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0021892	biolink:NamedThing	cerebral cortex GABAergic interneuron differentiation	The process in which a relatively unspecialized cell acquires specialized features of a GABAergic interneuron residing in the cerebral cortex.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0071404	biolink:NamedThing	cellular response to low-density lipoprotein particle stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a low-density lipoprotein particle stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to low-density lipoprotein particle|response to low density lipoprotein particle|response to low-density lipoprotein particle stimulus							mah	2009-12-14T02:51:57Z			GO:0055098		biological_process											owl:Class	
GO:0071402	biolink:NamedThing	cellular response to lipoprotein particle stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipoprotein particle stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-12-14T02:48:51Z					biological_process											owl:Class	
GO:0071864	biolink:NamedThing	positive regulation of cell proliferation in bone marrow	A process that activates or increases the frequency, rate or extent of cell proliferation in the bone marrow.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of bone marrow cell proliferation|up-regulation of cell proliferation in bone marrow|upregulation of cell proliferation in bone marrow|up regulation of cell proliferation in bone marrow|stimulation of cell proliferation in bone marrow|activation of cell proliferation in bone marrow							mah	2010-09-13T02:12:36Z					biological_process											owl:Class	
GO:0071863	biolink:NamedThing	regulation of cell proliferation in bone marrow	A process that modulates the frequency, rate or extent of cell proliferation in the bone marrow.	tmpzr1t_l9r_go_relaxed.owl	regulation of bone marrow cell proliferation							mah	2010-09-13T02:11:08Z					biological_process											owl:Class	
GO:1990484	biolink:NamedThing	aerobic lactate catabolic process	The chemical reactions and pathways resulting in the breakdown of lactate (2-hydroxypropanoic acid) in the presence of oxygen.	tmpzr1t_l9r_go_relaxed.owl	aerobic lactic acid catabolic process							tt	2014-09-20T05:42:51Z					biological_process											owl:Class	
GO:0060542	biolink:NamedThing	regulation of strand invasion	Any process that modulates the rate, frequency or extent of strand invasion. Strand invasion is the process in which the nucleoprotein complex (composed of the broken single-strand DNA and the recombinase) searches and identifies a region of homology in intact duplex DNA. The broken single-strand DNA displaces the like strand and forms Watson-Crick base pairs with its complement, forming a duplex in which each strand is from one of the two recombining DNA molecules.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-04-13T01:28:41Z					biological_process											owl:Class	
GO:0019476	biolink:NamedThing	D-lysine catabolic process	The chemical reactions and pathways resulting in the breakdown of D-lysine, the D-enantiomer of lysine; i.e. (2R)-2,6-diaminohexanoic acid.	tmpzr1t_l9r_go_relaxed.owl	D-lysine degradation|D-lysine catabolism|D-lysine breakdown													biological_process											owl:Class	
GO:0001812	biolink:NamedThing	positive regulation of type I hypersensitivity	Any process that activates or increases the frequency, rate or extent of type I hypersensitivity, a type of inflammatory response.	tmpzr1t_l9r_go_relaxed.owl	activation of type I hypersensitivity|up-regulation of type I hypersensitivity|upregulation of type I hypersensitivity|stimulation of type I hypersensitivity|up regulation of type I hypersensitivity													biological_process											owl:Class	
GO:0060665	biolink:NamedThing	regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling	Any process that modulates the rate, frequency, or extent of branching involved in salivary gland morphogenesis as a result of signals being generated by the mesenchyme and received and interpreted by the salivary gland epithelium.	tmpzr1t_l9r_go_relaxed.owl	regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signalling							dph	2009-06-01T08:42:36Z					biological_process											owl:Class	
GO:0032746	biolink:NamedThing	positive regulation of interleukin-22 production	Any process that activates or increases the frequency, rate, or extent of interleukin-22 production.	tmpzr1t_l9r_go_relaxed.owl	activation of interleukin-22 production|positive regulation of interleukin-22 biosynthetic process|positive regulation of IL-22 production|up regulation of interleukin-22 production|upregulation of interleukin-22 production|stimulation of interleukin-22 production|up-regulation of interleukin-22 production											GO:0045395		biological_process											owl:Class	
GO:0032666	biolink:NamedThing	regulation of interleukin-22 production	Any process that modulates the frequency, rate, or extent of interleukin-22 production.	tmpzr1t_l9r_go_relaxed.owl	regulation of interleukin-22 biosynthetic process|regulation of IL-22 production											GO:0045393		biological_process											owl:Class	
GO:0042306	biolink:NamedThing	regulation of protein import into nucleus	Any process that modulates the frequency, rate or extent of movement of proteins from the cytoplasm to the nucleus.	tmpzr1t_l9r_go_relaxed.owl	regulation of protein-nucleus import|regulation of protein transport from cytoplasm to nucleus|regulation of protein import into cell nucleus													biological_process											owl:Class	
GO:1902057	biolink:NamedThing	(25S)-Delta(4)-dafachronate metabolic process	The chemical reactions and pathways involving (25S)-Delta(4)-dafachronate.	tmpzr1t_l9r_go_relaxed.owl	(25S)-Delta(4)-dafachronate metabolism							ab	2013-04-13T09:22:54Z					biological_process											owl:Class	
GO:0007107	biolink:NamedThing	membrane addition at site of cytokinesis	Any process involved in the net addition of membrane at the site of cytokinesis; includes vesicle recruitment and fusion, local lipid synthesis and insertion.	tmpzr1t_l9r_go_relaxed.owl	cytokinesis, membrane recruitment/generation													biological_process											owl:Class	
GO:1904699	biolink:NamedThing	positive regulation of acinar cell proliferation	Any process that activates or increases the frequency, rate or extent of acinar cell proliferation.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of acinous cell proliferation|up regulation of acinous cell proliferation|up regulation of acinar cell proliferation|up regulation of acinic cell proliferation|upregulation of acinar cell proliferation|up-regulation of acinar cell proliferation|activation of acinous cell proliferation|up-regulation of acinic cell proliferation|activation of acinar cell proliferation|positive regulation of acinic cell proliferation|upregulation of acinous cell proliferation|positive regulation of acinous cell proliferation|activation of acinic cell proliferation|upregulation of acinic cell proliferation							sl	2015-09-30T15:20:03Z					biological_process											owl:Class	
GO:0035348	biolink:NamedThing	acetyl-CoA transmembrane transport	The process in which acetyl-CoA is transported across a membrane. Acetyl-CoA is a derivative of coenzyme A in which the sulfhydryl group is acetylated; it is a metabolite derived from several pathways (e.g. glycolysis, fatty acid oxidation, amino-acid catabolism) and is further metabolized by the tricarboxylic acid cycle. It is a key intermediate in lipid and terpenoid biosynthesis.	tmpzr1t_l9r_go_relaxed.owl	acetyl-CoA membrane transport					Note that this term is not intended for use in annotating lateral movement within membranes.		bf	2010-03-04T03:42:23Z					biological_process											owl:Class	
GO:0015876	biolink:NamedThing	acetyl-CoA transport	The directed movement of acetyl-CoA into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Acetyl-CoA is a derivative of coenzyme A in which the sulfhydryl group is acetylated; it is a metabolite derived from several pathways (e.g. glycolysis, fatty acid oxidation, amino-acid catabolism) and is further metabolized by the tricarboxylic acid cycle. It is a key intermediate in lipid and terpenoid biosynthesis.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1903103	biolink:NamedThing	potassium:proton antiporter complex	A protein complex which is capable of potassium:proton antiporter activity.	tmpzr1t_l9r_go_relaxed.owl						An example of this is kefC in E. coli (P03819) in PMID:21041667 (inferred from direct assay).		bhm	2014-06-04T20:51:33Z					cellular_component											owl:Class	
GO:2000918	biolink:NamedThing	regulation of glucuronoarabinoxylan catabolic process	Any process that modulates the frequency, rate or extent of glucuronoarabinoxylan catabolic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of glucuronoarabinoxylan catabolism							tt	2011-08-01T12:36:47Z					biological_process											owl:Class	
GO:2000915	biolink:NamedThing	regulation of glucuronoxylan catabolic process	Any process that modulates the frequency, rate or extent of glucuronoxylan catabolic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of glucuronoxylan catabolism							tt	2011-07-29T07:54:35Z					biological_process											owl:Class	
GO:1901927	biolink:NamedThing	cadinene catabolic process	The chemical reactions and pathways resulting in the breakdown of cadinene.	tmpzr1t_l9r_go_relaxed.owl	cadinene degradation|cadinene breakdown|cadinene catabolism							ms	2013-02-18T14:54:29Z					biological_process											owl:Class	
GO:1903073	biolink:NamedThing	negative regulation of death-inducing signaling complex assembly	Any process that stops, prevents or reduces the frequency, rate or extent of death-inducing signaling complex assembly.	tmpzr1t_l9r_go_relaxed.owl	downregulation of death domain-mediated complex assembly involved in extrinsic apoptotic pathway|down-regulation of DISC formation|down-regulation of death-inducing signaling complex assembly|down regulation of death-inducing signaling complex formation|inhibition of DISC formation|downregulation of DD-mediated complex assembly|down-regulation of death domain-mediated complex assembly|inhibition of death-inducing signaling complex assembly|negative regulation of death-inducing signalling complex assembly|down regulation of DISC assembly|inhibition of death-inducing signalling complex assembly|down-regulation of DISC assembly|negative regulation of DISC formation|downregulation of DISC assembly|negative regulation of DD-mediated complex assembly|down-regulation of DD-mediated complex assembly|down regulation of death-inducing signaling complex assembly|negative regulation of death domain-mediated complex assembly|down regulation of death domain-mediated complex assembly|down regulation of death domain-mediated complex assembly involved in extrinsic apoptotic pathway|down-regulation of death-inducing signalling complex assembly|down regulation of DD-mediated complex assembly|inhibition of death-inducing signaling complex formation|inhibition of DD-mediated complex assembly|negative regulation of death-inducing signaling complex formation|down-regulation of death domain-mediated complex assembly involved in extrinsic apoptotic pathway|downregulation of death domain-mediated complex assembly|downregulation of death-inducing signaling complex formation|negative regulation of DISC assembly|inhibition of death domain-mediated complex assembly involved in extrinsic apoptotic pathway|downregulation of death-inducing signalling complex assembly|down regulation of death-inducing signalling complex assembly|inhibition of death domain-mediated complex assembly|down regulation of DISC formation|inhibition of DISC assembly|down-regulation of death-inducing signaling complex formation|negative regulation of death domain-mediated complex assembly involved in extrinsic apoptotic pathway|downregulation of DISC formation|downregulation of death-inducing signaling complex assembly							bf	2014-05-29T09:33:20Z					biological_process											owl:Class	
GO:0072452	biolink:NamedThing	response to G2 transition size control checkpoint signaling	A process that occurs in response to signals generated as a result of G2/M transition size control checkpoint signaling.	tmpzr1t_l9r_go_relaxed.owl	response to signal involved in G2/M transition size control checkpoint|response to G2/M transition size control checkpoint signaling|G2/M transition size control checkpoint effector process|response to mitotic cell cycle G2/M transition size control checkpoint signaling							mah	2010-12-09T11:14:12Z					biological_process											owl:Class	
GO:0072470	biolink:NamedThing	response to cell size control checkpoint signaling	A process that occurs in response to signals generated as a result of cell size control checkpoint signaling.	tmpzr1t_l9r_go_relaxed.owl	response to signal involved in cell size control checkpoint|response to mitotic cell cycle cell size control checkpoint signaling|cell size control checkpoint effector process							mah	2010-12-09T11:46:13Z					biological_process											owl:Class	
GO:0070676	biolink:NamedThing	intralumenal vesicle formation	The invagination of the endosome membrane and resulting formation of a vesicle within the lumen of the endosome.	tmpzr1t_l9r_go_relaxed.owl	endosome membrane budding							mah	2009-05-29T02:02:30Z					biological_process											owl:Class	
GO:0006900	biolink:NamedThing	vesicle budding from membrane	The evagination of a membrane, resulting in formation of a vesicle.	tmpzr1t_l9r_go_relaxed.owl	single-organism membrane budding|vesicle budding|membrane evagination|single organism membrane budding|vesicle biosynthesis|nonselective vesicle assembly|vesicle formation							jl	2013-12-19T15:26:17Z			GO:1902591|GO:0006902		biological_process											owl:Class	
GO:0071904	biolink:NamedThing	protein N-linked N-acetylgalactosaminylation via asparagine	A process of protein N-linked glycosylation via asparagine in which N-acetylgalactosamine is added to the N4 of asparagine, forming an (S)-2-amino-4-(2-acetamido-2-deoxy-beta-D-galactopyranosyl)amino-4-oxobutanoic acid residue.	tmpzr1t_l9r_go_relaxed.owl	protein amino acid N-linked N-acetylgalactosaminylation via asparagine				RESID:AA0420			mah	2010-09-15T03:52:28Z					biological_process											owl:Class	
GO:0018218	biolink:NamedThing	peptidyl-cysteine phosphorylation	The phosphorylation of peptidyl-cysteine to form peptidyl-S-phospho-L-cysteine.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0034									biological_process											owl:Class	
GO:0072592	biolink:NamedThing	oxygen metabolic process	The chemical reactions and pathways involving diatomic oxygen (O2).	tmpzr1t_l9r_go_relaxed.owl	oxygen metabolism|diatomic oxygen metabolic process							mah	2011-02-11T10:46:51Z					biological_process											owl:Class	
GO:0030691	biolink:NamedThing	Noc2p-Noc3p complex	A heterodimer associated with 66S preribosomes; predominantly nucleoplasmic, but also locates to the nucleolus; involved in ribosomal large subunit biogenesis.	tmpzr1t_l9r_go_relaxed.owl						Noc complexes exhibit a dynamic intranuclear location; consider also annotating to 'nucleolus ; GO:0005730' and/or 'nucleoplasm ; GO:0005654'. Note that the term name uses Saccharomyces gene product names because no other names have yet arisen for this complex; the term nevertheless can be used for analogous complexes in other eukaryotes, and the name can be changed if better wording is found.								cellular_component											owl:Class	
GO:0030689	biolink:NamedThing	Noc complex	Any of several heterodimers containing one or two Noc proteins, associated with preribosomal complexes; involved in ribosome biogenesis.	tmpzr1t_l9r_go_relaxed.owl						Noc complexes exhibit a dynamic intranuclear location; consider also annotating to 'nucleolus ; GO:0005730' and/or 'nucleoplasm ; GO:0005654'. Note that the definition uses Saccharomyces gene product names because this complex has only been described in Saccharomyces cerevisiae and no other names have yet arisen; the term nevertheless can be used for analogous complexes in other eukaryotes, and the definition can be changed if better wording is found.								cellular_component											owl:Class	
GO:0015419	biolink:NamedThing	ABC-type sulfate transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + sulfate(out) = ADP + phosphate + sulfate(in).	tmpzr1t_l9r_go_relaxed.owl	sulfate transmembrane-transporting ATPase activity|sulfate/thiosulfate porter activity|ATPase-coupled sulfate transmembrane transporter activity|sulfate ABC transporter|sulfate-transporting ATPase activity|sulphate transporting ATPase activity				RHEA:10192|MetaCyc:3.6.3.25-RXN|EC:7.3.2.3									molecular_function											owl:Class	
GO:0051364	biolink:NamedThing	N-terminal peptidyl-proline N-formylation	The formylation of the N-terminal proline of proteins to form the derivative N-formylproline.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0384									biological_process											owl:Class	
GO:0051926	biolink:NamedThing	negative regulation of calcium ion transport	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of calcium ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of calcium ion transport|inhibition of calcium ion transport|negative regulation of calcium transport|down regulation of calcium ion transport|downregulation of calcium ion transport													biological_process											owl:Class	
GO:0103077	biolink:NamedThing	quercetin 3-glucoside 7-O-rhamnosyltransferase activity	Catalysis of the reaction: quercetin-3-glucoside + UDP-L-rhamnose <=> quercetin-3-O-glucoside-7-O-rhamnoside + UDP.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXNQT-4161|RHEA:61188									molecular_function											owl:Class	
GO:0106140	biolink:NamedThing	P-TEFb complex binding	Binding to a P-TEFb complex.	tmpzr1t_l9r_go_relaxed.owl								hjd	2018-08-17T18:17:50Z					molecular_function											owl:Class	
GO:1904140	biolink:NamedThing	negative regulation of microglial cell migration	Any process that stops, prevents or reduces the frequency, rate or extent of microglial cell migration.	tmpzr1t_l9r_go_relaxed.owl	down regulation of microglial cell migration|downregulation of microglial cell migration|down-regulation of microglial cell migration|inhibition of microglial cell migration							nc	2015-04-13T09:07:03Z					biological_process											owl:Class	
GO:1905522	biolink:NamedThing	negative regulation of macrophage migration	Any process that stops, prevents or reduces the frequency, rate or extent of macrophage migration.	tmpzr1t_l9r_go_relaxed.owl	down regulation of macrophage migration|inhibition of macrophage migration|down-regulation of macrophage migration|downregulation of macrophage migration							sl	2016-10-03T15:29:14Z					biological_process											owl:Class	
GO:0070893	biolink:NamedThing	transposon integration	Any process in which a transposable element is incorporated into another DNA molecule such as a chromosome.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-09-01T04:08:19Z					biological_process											owl:Class	
GO:0015074	biolink:NamedThing	DNA integration	The process in which a DNA segment is incorporated into another, usually larger, DNA molecule such as a chromosome.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0019648	biolink:NamedThing	formaldehyde assimilation via xylulose monophosphate cycle	The pathway in which formaldehyde is used as a carbon source in the xylulose monophosphate cycle. Methylotrophic yeasts, but not bacteria, utilize the xylulose monophosphate cycle to fix formaldehyde and convert it into metabolically useful organic compounds.	tmpzr1t_l9r_go_relaxed.owl	formaldehyde fixation cycle|formaldehyde assimilation via xylulose-5-phosphate cycle				MetaCyc:P185-PWY									biological_process											owl:Class	
GO:0072382	biolink:NamedThing	minus-end-directed vesicle transport along microtubule	The directed movement of a vesicle towards the minus end of a microtubule, mediated by motor proteins. This process begins with the attachment of a vesicle to a microtubule, and ends when the vesicle reaches its final destination.	tmpzr1t_l9r_go_relaxed.owl	microtubule minus-end-directed vesicle distribution|microtubule minus-end-directed vesicle localization							mah	2010-12-01T04:12:59Z					biological_process											owl:Class	
GO:0047496	biolink:NamedThing	vesicle transport along microtubule	The directed movement of a vesicle along a microtubule, mediated by motor proteins. This process begins with the attachment of a vesicle to a microtubule, and ends when the vesicle reaches its final destination.	tmpzr1t_l9r_go_relaxed.owl	microtubule-based vesicle localization													biological_process											owl:Class	
GO:0004644	biolink:NamedThing	phosphoribosylglycinamide formyltransferase activity	Catalysis of the reaction: 10-formyltetrahydrofolate + N1-(5-phospho-D-ribosyl)glycinamide = tetrahydrofolate + N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide.	tmpzr1t_l9r_go_relaxed.owl	glycinamide ribonucleotide transformylase activity|GAR transformylase activity|GAR TFase activity|5'-phosphoribosylglycinamide transformylase activity|GAR formyltransferase activity|2-amino-N-ribosylacetamide 5'-phosphate transformylase activity|GART activity|10-formyltetrahydrofolate:5'-phosphoribosylglycinamide N-formyltransferase activity|5,10-methenyltetrahydrofolate:2-amino-N-ribosylacetamide ribonucleotide transformylase activity				MetaCyc:GART-RXN|Reactome:R-HSA-73813|RHEA:15053|EC:2.1.2.2									molecular_function											owl:Class	
GO:0016742	biolink:NamedThing	hydroxymethyl-, formyl- and related transferase activity	Catalysis of the transfer of a hydroxymethyl- or formyl group from one compound (donor) to another (acceptor).	tmpzr1t_l9r_go_relaxed.owl					EC:2.1.2.-									molecular_function											owl:Class	
GO:0018164	biolink:NamedThing	protein-DNA covalent cross-linking via peptidyl-threonine	The formation of a covalent cross-link between DNA and a peptidyl-threonine residue by the formation of O-(phospho-5'-DNA)-L-threonine.	tmpzr1t_l9r_go_relaxed.owl	DNA-protein covalent cross-linking via peptidyl-threonine				RESID:AA0255									biological_process											owl:Class	
GO:1900360	biolink:NamedThing	regulation of pentasaccharide transport	Any process that modulates the frequency, rate or extent of pentasaccharide transport.	tmpzr1t_l9r_go_relaxed.owl								tt	2012-04-06T02:19:27Z					biological_process											owl:Class	
GO:1903028	biolink:NamedThing	positive regulation of opsonization	Any process that activates or increases the frequency, rate or extent of opsonization.	tmpzr1t_l9r_go_relaxed.owl	upregulation of opsonization|up regulation of opsonization|activation of opsonization|up-regulation of opsonization							rl	2014-05-16T17:34:54Z					biological_process											owl:Class	
GO:0050766	biolink:NamedThing	positive regulation of phagocytosis	Any process that activates or increases the frequency, rate or extent of phagocytosis.	tmpzr1t_l9r_go_relaxed.owl	activation of phagocytosis|up regulation of phagocytosis|upregulation of phagocytosis|up-regulation of phagocytosis|stimulation of phagocytosis													biological_process											owl:Class	
GO:0072304	biolink:NamedThing	regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis	Any process that modulates the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the metanephros.	tmpzr1t_l9r_go_relaxed.owl	regulation of mesenchymal stem cell apoptosis involved in metanephric nephron morphogenesis|regulation of mesenchymal stem cell apoptotic process involved in metanephric nephron morphogenesis							mah	2010-04-09T05:03:41Z					biological_process											owl:Class	
GO:0072039	biolink:NamedThing	regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis	Any process that modulates the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron.	tmpzr1t_l9r_go_relaxed.owl	regulation of mesenchymal stem cell apoptosis involved in nephron morphogenesis|regulation of mesenchymal stem cell apoptotic process involved in nephron morphogenesis							mah	2010-01-25T03:08:34Z					biological_process											owl:Class	
GO:0110028	biolink:NamedThing	positive regulation of mitotic spindle organization	Any process that activates or increases the frequency, rate or extent of mitotic spindle organization.	tmpzr1t_l9r_go_relaxed.owl								kmv	2017-07-06T14:14:08Z					biological_process											owl:Class	
GO:0015533	biolink:NamedThing	shikimate:proton symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: shikimate(out) + H+(out) = shikimate(in) + H+(in).	tmpzr1t_l9r_go_relaxed.owl	shikimate:hydrogen symporter activity													molecular_function											owl:Class	
GO:1902321	biolink:NamedThing	methyl-branched fatty acid biosynthetic process	The chemical reactions and pathways resulting in the formation of methyl-branched fatty acid.	tmpzr1t_l9r_go_relaxed.owl	methyl-branched fatty acid biosynthesis|methyl-branched fatty acid formation|methyl-branched fatty acid anabolism|methyl-branched fatty acid synthesis							kmv	2013-07-23T20:40:46Z					biological_process											owl:Class	
GO:1905529	biolink:NamedThing	regulation of uracil import across plasma membrane	Any process that modulates the frequency, rate or extent of uracil import across plasma membrane.	tmpzr1t_l9r_go_relaxed.owl								vw	2016-10-05T21:03:40Z					biological_process											owl:Class	
GO:0003916	biolink:NamedThing	DNA topoisomerase activity	Catalysis of the transient cleavage and passage of individual DNA strands or double helices through one another, resulting a topological transformation in double-stranded DNA.	tmpzr1t_l9r_go_relaxed.owl					EC:5.6.2.-							GO:0009387		molecular_function											owl:Class	
GO:0033132	biolink:NamedThing	negative regulation of glucokinase activity	Any process that stops, prevents, or reduces the frequency, rate or extent of glucokinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a glucose molecule.	tmpzr1t_l9r_go_relaxed.owl	inhibition of glucokinase activity|downregulation of glucokinase activity|down regulation of glucokinase activity|down-regulation of glucokinase activity|glucokinase inhibitor													biological_process											owl:Class	
GO:1903300	biolink:NamedThing	negative regulation of hexokinase activity	Any process that stops, prevents or reduces the frequency, rate or extent of hexokinase activity.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of hexokinase type III activity|inhibition of hexokinase (phosphorylating)|negative regulation of hexokinase D|downregulation of hexokinase type IV (glucokinase) activity|down regulation of hexokinase type IV (glucokinase) activity|inhibition of ATP-dependent hexokinase activity|down-regulation of ATP:D-hexose 6-phosphotransferase activity|downregulation of hexokinase D|negative regulation of hexokinase type IV glucokinase activity|downregulation of hexokinase type I activity|negative regulation of ATP-dependent hexokinase activity|down-regulation of hexokinase type I activity|inhibition of hexokinase type II activity|down regulation of hexokinase type IV|down regulation of ATP:D-hexose 6-phosphotransferase activity|down regulation of hexokinase activity|down regulation of hexokinase type II activity|down-regulation of ATP-dependent hexokinase activity|inhibition of hexokinase activity|negative regulation of hexokinase type II activity|inhibition of hexokinase type I activity|down-regulation of hexokinase type IV|downregulation of ATP-dependent hexokinase activity|downregulation of ATP:D-hexose 6-phosphotransferase activity|downregulation of hexokinase type IV|down-regulation of hexokinase activity|negative regulation of glucose ATP phosphotransferase activity|down regulation of ATP-dependent hexokinase activity|down regulation of hexokinase D|downregulation of hexokinase (phosphorylating)|negative regulation of hexokinase type IV|down-regulation of hexokinase D|negative regulation of hexokinase type III activity|down-regulation of hexokinase type IV glucokinase activity|downregulation of hexokinase type IV glucokinase activity|negative regulation of hexokinase (phosphorylating)|downregulation of hexokinase activity|down-regulation of hexokinase (phosphorylating)|downregulation of hexokinase type II activity|down regulation of hexokinase type IV glucokinase activity|down regulation of glucose ATP phosphotransferase activity|downregulation of glucose ATP phosphotransferase activity|inhibition of hexokinase type III activity|inhibition of hexokinase type IV glucokinase activity|inhibition of glucose ATP phosphotransferase activity|down regulation of hexokinase type III activity|negative regulation of hexokinase type I activity|negative regulation of hexokinase type IV (glucokinase) activity|down-regulation of hexokinase type IV (glucokinase) activity|down-regulation of glucose ATP phosphotransferase activity|down-regulation of hexokinase type II activity|inhibition of hexokinase D|inhibition of ATP:D-hexose 6-phosphotransferase activity|inhibition of hexokinase type IV (glucokinase) activity|inhibition of hexokinase type IV|negative regulation of ATP:D-hexose 6-phosphotransferase activity|down regulation of hexokinase (phosphorylating)|downregulation of hexokinase type III activity|down regulation of hexokinase type I activity							mr	2014-08-15T23:18:01Z					biological_process											owl:Class	
GO:0099091	biolink:NamedThing	postsynaptic specialization, intracellular component	A network of proteins adjacent to the postsynaptic membrane. Its major components include the proteins that spatially and functionally organize neurotransmitter receptors in the adjacent membrane, such as anchoring and scaffolding molecules, signaling enzymes and cytoskeletal components.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0060860	biolink:NamedThing	regulation of floral organ abscission	Any process that modulates the rate, frequency, or extent of floral organ abscission, the controlled shedding of floral organs.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-08-12T03:59:45Z					biological_process											owl:Class	
GO:0001788	biolink:NamedThing	antibody-dependent cellular cytotoxicity	Cytolysis of target cells by natural killer cells, eosinophils, neutrophils, monocytes, or macrophages following engagement of antibodies bound to the target cells by Fc receptors on the effector cells.	tmpzr1t_l9r_go_relaxed.owl	antibody-dependent cell killing|antibody-dependent cell death|ADCC|antibody dependent cell death|antibody dependent cell killing|type VI hypersensitivity				Wikipedia:Antibody-dependent_cell-mediated_cytotoxicity|Wikipedia:Antibody-dependent_cellular_cytotoxicity									biological_process											owl:Class	
GO:0016748	biolink:NamedThing	succinyltransferase activity	Catalysis of the transfer of a succinyl (3-carboxypropanoyl) group to an acceptor molecule.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0016082	biolink:NamedThing	synaptic vesicle priming	A process that converts synaptic vesicles to a state of competence for calcium triggered fusion with the active zone membrane by bringing the two membranes into very close proximity. Priming typically (but not always) occurs after docking (Jahn and Fasshauer, 2012). Primed vesicles are also capable of spontaneously fusing with the active zone membrane.	tmpzr1t_l9r_go_relaxed.owl						Although this process can occur outside of synaptic transmission, by convention we treat it as a part of synaptic transmission.  (dos, pvn, fk synapse project 2015)								biological_process											owl:Class	
GO:0046668	biolink:NamedThing	regulation of retinal cell programmed cell death	Any process that modulates the frequency, rate or extent of programmed cell death that occurs in the retina.	tmpzr1t_l9r_go_relaxed.owl	regulation of retinal programmed cell death													biological_process											owl:Class	
GO:2000895	biolink:NamedThing	hemicellulose catabolic process	The chemical reactions and pathways resulting in the breakdown of a hemicellulose.	tmpzr1t_l9r_go_relaxed.owl	hemicellulose catabolism							jl	2011-07-28T02:08:11Z					biological_process											owl:Class	
GO:0072000	biolink:NamedThing	extracellular polysaccharide catabolic process involved in ascospore release from ascus	The chemical reactions and pathways resulting in the breakdown of polysaccharides in the ascus wall that contributes to the release of ascospores from the ascus.	tmpzr1t_l9r_go_relaxed.owl	ascus endolysis|extracellular polysaccharide degradation involved in ascospore release from ascus|extracellular polysaccharide catabolism involved in ascospore release from ascus|ascus catabolic process|extracellular polysaccharide breakdown involved in ascospore release from ascus							mah	2010-10-25T05:30:41Z					biological_process											owl:Class	
GO:0032481	biolink:NamedThing	positive regulation of type I interferon production	Any process that activates or increases the frequency, rate, or extent of type I interferon production. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families.	tmpzr1t_l9r_go_relaxed.owl	activation of type I interferon production|up regulation of type I interferon production|up-regulation of type I interferon production|stimulation of type I interferon production|positive regulation of type I IFN production|upregulation of type I interferon production													biological_process											owl:Class	
GO:0032479	biolink:NamedThing	regulation of type I interferon production	Any process that modulates the frequency, rate, or extent of interferon type I production. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families.	tmpzr1t_l9r_go_relaxed.owl	regulation of type I IFN production													biological_process											owl:Class	
GO:0039011	biolink:NamedThing	pronephric proximal tubule morphogenesis	The process in which the anatomical structures of a pronephric nephron proximal tubule are generated and organized. A pronephric nephron tubule is an epithelial tube that is part of the pronephros.	tmpzr1t_l9r_go_relaxed.owl	pronephros proximal tubule morphogenesis							bf	2010-07-02T09:53:12Z					biological_process											owl:Class	
GO:0072158	biolink:NamedThing	proximal tubule morphogenesis	The process in which the anatomical structures of a proximal tubule are generated and organized. The proximal tubule is a nephron tubule that connects Bowman's capsule to the descending thin limb of the loop of Henle. It has a brush border epithelial morphology.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-02-24T02:35:36Z					biological_process											owl:Class	
GO:0044284	biolink:NamedThing	mitochondrial crista junction	A tubular structure of relatively uniform size that connects a mitochondrial crista to the mitochondrial inner boundary membrane.	tmpzr1t_l9r_go_relaxed.owl	crista junction|cristae junction	https://github.com/geneontology/go-ontology/issues/18994						jl	2010-02-02T10:07:39Z					cellular_component											owl:Class	
GO:0044232	biolink:NamedThing	organelle membrane contact site	A zone of apposition between the membranes of an organelle with another membrane, either another membrane of the same organelle, a membrane of another organelle, or the plasma membrane. Membrane contact sites (MCSs) are structured by bridging complexes. They are specialized for communication, including the efficient traffic of small molecules such as Ca2+ ions and lipids, as well as enzyme-substrate interactions.	tmpzr1t_l9r_go_relaxed.owl	inter-organelle junction|MCS|interorganelle junction	https://github.com/geneontology/go-ontology/issues/18994						jl	2010-01-07T03:44:20Z					cellular_component											owl:Class	
GO:0062209	biolink:NamedThing	spatial regulation of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination	Any process that modulates the distribution of sites along the chromosome where meiotic DNA double-strand break formation takes place as part of reciprocal meiotic recombination.	tmpzr1t_l9r_go_relaxed.owl	regulation of spatial distribution of meiotic DSB formation involved in reciprocal meiotic recombination|crossover interference|regulation of spatial distribution of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination|DSB interference							dph	2020-02-03T19:19:29Z					biological_process											owl:Class	
GO:2000324	biolink:NamedThing	positive regulation of glucocorticoid receptor signaling pathway	Any process that activates or increases the frequency, rate or extent of glucocorticoid receptor signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of glucocorticoid receptor signalling pathway							vk	2011-01-18T04:39:05Z					biological_process											owl:Class	
GO:0140449	biolink:NamedThing	centromere-nuclear envelope anchor activity	The binding activity of a molecule that brings together the centromeric region of a chromosome and the inner nuclear membrane by interacting with both the centromere/kinetochore complex and the nuclear membrane, in order to establish and maintain the centromere/kinetochore location.	tmpzr1t_l9r_go_relaxed.owl	centromere-inner nuclear envelope tether activity|chromosome, centromeric region-nuclear envelope anchor activity|centromere nuclear envelope tether activity|nuclear envelope-centromere tether activity|nuclear envelope-centromere anchor activity|centromere-inner nuclear envelope anchor activity|centromere nuclear envelope anchor activity	https://github.com/geneontology/go-ontology/issues/19227						pg	2020-04-07T06:27:08Z					molecular_function											owl:Class	
GO:0043495	biolink:NamedThing	protein-membrane adaptor activity	The binding activity of a molecule that brings together a protein or a protein complex with a membrane, or bringing together two membranes, either via membrane lipid binding or by interacting with a membrane protein, to establish or maintain the localization of the protein, protein complex or organelle.	tmpzr1t_l9r_go_relaxed.owl	protein membrane adaptor|anchoring|protein membrane anchor|protein membrane adaptor activity	https://github.com/geneontology/go-ontology/issues/19090												molecular_function											owl:Class	
GO:0032873	biolink:NamedThing	negative regulation of stress-activated MAPK cascade	Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the stress-activated MAPK cascade.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of stress-activated MAPK cascade|negative regulation of stress-activated MAPK signalling pathway|downregulation of stress-activated MAPK cascade|negative regulation of stress-activated MAPKKK cascade|negative regulation of stress-activated MAPK signaling pathway|inhibition of stress-activated MAPK cascade|negative regulation of p38 MAPK signaling|negative regulation of stress-activated MAPKKK signalling pathway|negative regulation of p38 MAPK signalling|negative regulation of stress-activated MAPKKK signaling pathway|down regulation of stress-activated MAPK cascade													biological_process											owl:Class	
GO:0019841	biolink:NamedThing	retinol binding	Binding to retinol, vitamin A1, 2,6,6-trimethyl-1-(9'-hydroxy-3',7'-dimethylnona-1',3',5',7'-tetraenyl)cyclohex-1-ene, one of the three components that makes up vitamin A. Retinol is an intermediate in the vision cycle and it also plays a role in growth and differentiation.	tmpzr1t_l9r_go_relaxed.owl	vitamin A1 binding|vitamin A1 alcohol binding													molecular_function											owl:Class	
GO:0052322	biolink:NamedThing	positive regulation of phytoalexin biosynthetic process	Any process that activates, maintains or increases the frequency, rate or extent of phytoalexin biosynthesis, the chemical reactions and pathways resulting in the formation of phytoalexins.	tmpzr1t_l9r_go_relaxed.owl	stimulation of phytoalexin biosynthesis|up regulation of phytoalexin biosynthesis|activation of phytoalexin biosynthesis|up-regulation of phytoalexin biosynthesis|positive regulation of phytoalexin biosynthesis|upregulation of phytoalexin biosynthesis													biological_process											owl:Class	
GO:0052320	biolink:NamedThing	positive regulation of phytoalexin metabolic process	Any process that activates, maintains or increases the frequency, rate or extent of phytoalexin metabolism, the chemical reactions and pathways involving phytoalexins.	tmpzr1t_l9r_go_relaxed.owl	stimulation of phytoalexin metabolism|up regulation of phytoalexin metabolism|activation of phytoalexin metabolism|upregulation of phytoalexin metabolism|positive regulation of phytoalexin metabolism|up-regulation of phytoalexin metabolism													biological_process											owl:Class	
GO:0062089	biolink:NamedThing	regulation of taurine biosynthetic process	Any process that modulates the rate, frequency or extent of taurine biosynthesis.	tmpzr1t_l9r_go_relaxed.owl								dph	2018-11-07T14:05:44Z					biological_process											owl:Class	
GO:0098906	biolink:NamedThing	regulation of Purkinje myocyte action potential	Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a Purkinje myocyte. This typically occurs via modulation of the activity or expression of voltage-gated ion channels.	tmpzr1t_l9r_go_relaxed.owl								tb	2011-11-10T08:58:56Z					biological_process											owl:Class	
GO:0042491	biolink:NamedThing	inner ear auditory receptor cell differentiation	The process in which a relatively unspecialized inner cell acquires specialized features of an auditory hair cell.	tmpzr1t_l9r_go_relaxed.owl	auditory receptor cell differentiation|auditory hair cell differentiation					Note that this term refers to the mechanosensory hair cells of the inner ear.								biological_process											owl:Class	
GO:0060113	biolink:NamedThing	inner ear receptor cell differentiation	The process in which relatively unspecialized cells, acquire specialized structural and/or functional features of inner ear receptor cells. Inner ear receptor cells are mechanorecptors found in the inner ear responsible for transducing signals involved in balance and sensory perception of sound.	tmpzr1t_l9r_go_relaxed.owl	inner ear hair cell differentiation													biological_process											owl:Class	
GO:0042634	biolink:NamedThing	regulation of hair cycle	Any process that modulates the frequency, rate or extent of the cyclical phases of growth (anagen), regression (catagen), quiescence (telogen), and shedding (exogen) in the life of a hair.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0071693	biolink:NamedThing	protein transport within extracellular region	The directed movement of proteins in the extracellular region, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-02-25T04:02:35Z					biological_process											owl:Class	
GO:0035592	biolink:NamedThing	establishment of protein localization to extracellular region	The directed movement of a protein to a specific location within the extracellular region.	tmpzr1t_l9r_go_relaxed.owl	establishment of protein localisation in extracellular region|establishment of protein localization in extracellular region							bf	2010-11-09T10:25:08Z					biological_process											owl:Class	
GO:1904506	biolink:NamedThing	negative regulation of telomere maintenance in response to DNA damage	Any process that stops, prevents or reduces the frequency, rate or extent of telomere maintenance in response to DNA damage.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of telomere maintenance in response to DNA damage|down regulation of telomere maintenance in response to DNA damage|down regulation of DNA damage response, telomere maintenance|downregulation of DNA damage response, telomere maintenance|negative regulation of DNA damage response, telomere maintenance|downregulation of telomere maintenance in response to DNA damage|down-regulation of DNA damage response, telomere maintenance|inhibition of telomere maintenance in response to DNA damage|inhibition of DNA damage response, telomere maintenance							nc	2015-07-24T16:06:02Z					biological_process											owl:Class	
GO:0034631	biolink:NamedThing	microtubule anchoring at spindle pole body	Any process in which a microtubule is maintained in a specific location in a cell by attachment to a spindle pole body. Microtubules attach to spindle pole bodies at the minus end.	tmpzr1t_l9r_go_relaxed.owl	attachment of spindle microtubules to spindle pole body|microtubule anchoring at SPB|attachment of spindle microtubules to SPB													biological_process											owl:Class	
GO:0014842	biolink:NamedThing	regulation of skeletal muscle satellite cell proliferation	Any process that modulates the frequency, rate or extent of skeletal muscle satellite cell proliferation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0014857	biolink:NamedThing	regulation of skeletal muscle cell proliferation	Any process that modulates the frequency, rate or extent of skeletal muscle cell proliferation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0051284	biolink:NamedThing	positive regulation of sequestering of calcium ion	Any process that activates or increases the frequency, rate or extent of the binding or confining calcium ions such that they are separated from other components of a biological system.	tmpzr1t_l9r_go_relaxed.owl	up regulation of sequestering of calcium ion|positive regulation of storage of calcium ion (Ca2+)|positive regulation of sequestering of calcium ion (Ca2+)|activation of sequestering of calcium ion|positive regulation of sequestration of calcium ion (Ca2+)|positive regulation of calcium ion (Ca2+) sequestering|positive regulation of calcium ion (Ca2+) retention|stimulation of sequestering of calcium ion|positive regulation of calcium ion (Ca2+) sequestration|positive regulation of calcium ion (Ca2+) storage|positive regulation of retention of calcium ion (Ca2+)|up-regulation of sequestering of calcium ion|upregulation of sequestering of calcium ion													biological_process											owl:Class	
GO:0009709	biolink:NamedThing	terpenoid indole alkaloid biosynthetic process	The chemical reactions and pathways resulting in the formation of terpenoid indole alkaloids, compounds formed from the condensation of tryptamine (derived from tryptophan) and secologanin (derived from geranyl pyrophosphate).	tmpzr1t_l9r_go_relaxed.owl	terpenoid indole alkaloid synthesis|terpenoid indole alkaloid formation|terpenoid indole alkaloid biosynthesis|terpenoid indole alkaloid anabolism													biological_process											owl:Class	
GO:1902154	biolink:NamedThing	positive regulation of response to DNA damage checkpoint signaling	Any process that activates or increases the frequency, rate or extent of response to DNA damage checkpoint signaling.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of DNA damage checkpoint effector process|upregulation of response to signal involved in DNA damage checkpoint|up-regulation of response to signal involved in DNA damage checkpoint|activation of response to signal involved in DNA damage checkpoint|upregulation of DNA damage checkpoint effector process|positive regulation of response to signal involved in DNA damage checkpoint|up regulation of DNA damage checkpoint effector process|up regulation of response to DNA damage checkpoint signaling|activation of response to DNA damage checkpoint signaling|up-regulation of DNA damage checkpoint effector process|up-regulation of response to DNA damage checkpoint signaling|upregulation of response to DNA damage checkpoint signaling|activation of DNA damage checkpoint effector process|up regulation of response to signal involved in DNA damage checkpoint							jl	2013-05-21T15:44:44Z					biological_process											owl:Class	
GO:0010594	biolink:NamedThing	regulation of endothelial cell migration	Any process that modulates the rate, frequency, or extent of the orderly movement of an endothelial cell into the extracellular matrix to form an endothelium.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0010632	biolink:NamedThing	regulation of epithelial cell migration	Any process that modulates the frequency, rate or extent of epithelial cell migration.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0045637	biolink:NamedThing	regulation of myeloid cell differentiation	Any process that modulates the frequency, rate or extent of myeloid cell differentiation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0061805	biolink:NamedThing	mitotic spindle elongation (spindle phase three)	The cell cycle process in which the distance is lengthened between poles of the mitotic spindle during mitotic anaphase B.	tmpzr1t_l9r_go_relaxed.owl	mitotic spindle elongation during mitotic anaphase|mitotic spindle elongation during anaphase|mitotic anaphase spindle elongation							dph	2016-11-06T23:09:43Z					biological_process											owl:Class	
GO:0007052	biolink:NamedThing	mitotic spindle organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the microtubule spindle during a mitotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl	mitotic spindle organization in nucleus|mitotic spindle organization and biogenesis in cell nucleus|mitotic spindle organization and biogenesis in nucleus|spindle organization and biogenesis during mitosis|mitotic spindle stabilization|spindle organization and biogenesis in nucleus during mitosis|mitotic spindle organization and biogenesis|mitotic spindle organisation|mitotic spindle organisation in nucleus	https://github.com/geneontology/go-ontology/issues/15341				In fission yeast most mitotic spindle organization occurs in the nucleus.						GO:0030472|GO:0043148|GO:0000071		biological_process											owl:Class	
GO:0004917	biolink:NamedThing	interleukin-7 receptor activity	Combining with interleukin-7 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	IL-7R|IL-7 receptor activity													molecular_function											owl:Class	
GO:0097744	biolink:NamedThing	urate salt excretion	The elimination by an organism of urate salt or uric acid.	tmpzr1t_l9r_go_relaxed.owl	urate excretion							pr	2016-10-27T11:35:59Z					biological_process											owl:Class	
GO:0007588	biolink:NamedThing	excretion	The elimination by an organism of the waste products that arise as a result of metabolic activity. These products include water, carbon dioxide (CO2), and nitrogenous compounds.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Excretion									biological_process											owl:Class	
GO:1901922	biolink:NamedThing	regulation of sclerotium development	Any process that modulates the frequency, rate or extent of sclerotium development.	tmpzr1t_l9r_go_relaxed.owl								di	2013-02-15T20:00:19Z					biological_process											owl:Class	
GO:0009732	biolink:NamedThing	detection of hexose stimulus	The series of events in which a stimulus from a hexose is received and converted into a molecular signal.	tmpzr1t_l9r_go_relaxed.owl	perception of hexose stimulus													biological_process											owl:Class	
GO:0034287	biolink:NamedThing	detection of monosaccharide stimulus	The series of events in which a stimulus from a monosaccharide is received and converted into a molecular signal.	tmpzr1t_l9r_go_relaxed.owl	perception of monosaccharide stimulus													biological_process											owl:Class	
GO:0102553	biolink:NamedThing	lipoyl synthase activity (acting on pyruvate dehydrogenase E2 protein)	Catalysis of the reaction: 2 S-adenosyl-L-methionine  + a [pyruvate dehydrogenase E2 protein] N6-octanoyl-L-lysine + 2 a sulfurated [sulfur carrier] = 2 L-methionine  + 2 5'-deoxyadenosine + 2 H+ + a [pyruvate dehydrogenase E2 protein] N6-lipoyl-L-lysine + 2 an unsulfurated [sulfur carrier].	tmpzr1t_l9r_go_relaxed.owl					EC:2.8.1.8|MetaCyc:RXN-14957									molecular_function											owl:Class	
GO:0004866	biolink:NamedThing	endopeptidase inhibitor activity	Binds to and stops, prevents or reduces the activity of an endopeptidase, any enzyme that hydrolyzes nonterminal peptide bonds in polypeptides.	tmpzr1t_l9r_go_relaxed.owl	proteinase inhibitor|endoproteinase inhibitor|alpha-2 macroglobulin													molecular_function											owl:Class	
GO:1902310	biolink:NamedThing	positive regulation of peptidyl-serine dephosphorylation	Any process that activates or increases the frequency, rate or extent of peptidyl-serine dephosphorylation.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of peptidyl-serine dephosphorylation|upregulation of peptidyl-serine dephosphorylation|activation of peptidyl-serine dephosphorylation|up regulation of peptidyl-serine dephosphorylation							rl	2013-07-19T10:35:15Z					biological_process											owl:Class	
GO:1902308	biolink:NamedThing	regulation of peptidyl-serine dephosphorylation	Any process that modulates the frequency, rate or extent of peptidyl-serine dephosphorylation.	tmpzr1t_l9r_go_relaxed.owl								rl	2013-07-19T10:34:59Z					biological_process											owl:Class	
GO:2000734	biolink:NamedThing	negative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation	Any process that stops, prevents or reduces the frequency, rate or extent of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of glial cell-derived neurotrophic factor receptor signalling pathway of ureteric bud formation|negative regulation of glial cell derived neurotrophic factor receptor signaling pathway of ureteric bud formation|negative regulation of glial cell line-derived neurotrophic factor receptor signalling pathway of ureteric bud formation|negative regulation of GDNF receptor signaling pathway of ureteric bud formation|negative regulation of glial cell-derived neurotrophic factor receptor signaling pathway of ureteric bud formation							yaf	2011-06-13T11:14:44Z					biological_process											owl:Class	
GO:2000904	biolink:NamedThing	regulation of starch metabolic process	Any process that modulates the frequency, rate or extent of starch metabolic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of starch metabolism							tb	2011-07-28T11:33:13Z					biological_process											owl:Class	
GO:0046125	biolink:NamedThing	pyrimidine deoxyribonucleoside metabolic process	The chemical reactions and pathways involving any one of a family of organic molecules consisting of a pyrimidine base covalently bonded to a sugar deoxyribose (a deoxyribonucleoside).	tmpzr1t_l9r_go_relaxed.owl	pyrimidine deoxyribonucleoside metabolism													biological_process											owl:Class	
GO:0047159	biolink:NamedThing	1-alkenylglycerophosphocholine O-acyltransferase activity	Catalysis of the reaction: 1-alkenylglycerophosphocholine + acyl-CoA = 1-alkenyl-2-acylglycerophosphocholine + CoA.	tmpzr1t_l9r_go_relaxed.owl	acyl-CoA:1-alkenylglycerophosphocholine O-acyltransferase activity				EC:2.3.1.25|MetaCyc:2.3.1.104-RXN|RHEA:10344									molecular_function											owl:Class	
GO:0098993	biolink:NamedThing	anchored component of synaptic vesicle membrane	The component of the synaptic vesicle membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0098563	biolink:NamedThing	intrinsic component of synaptic vesicle membrane	The component of the synaptic vesicle membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0051124	biolink:NamedThing	synaptic assembly at neuromuscular junction	The assembly of a synapse at a neuromuscular junction.	tmpzr1t_l9r_go_relaxed.owl	synaptic growth at neuromuscular junction|cholinergic synaptogenesis													biological_process											owl:Class	
GO:0007416	biolink:NamedThing	synapse assembly	The aggregation, arrangement and bonding together of a set of components to form a synapse.  This process ends when the synapse is mature (functional).	tmpzr1t_l9r_go_relaxed.owl	synapse biogenesis|synaptogenesis				Wikipedia:Synaptogenesis									biological_process											owl:Class	
GO:1901232	biolink:NamedThing	regulation of convergent extension involved in axis elongation	Any process that modulates the frequency, rate or extent of convergent extension involved in axis elongation.	tmpzr1t_l9r_go_relaxed.owl								vk	2012-08-07T14:21:46Z					biological_process											owl:Class	
GO:0047321	biolink:NamedThing	diphosphate-protein phosphotransferase activity	Catalysis of the reaction: microsomal-membrane protein + diphosphate = diphosphate + O-phospho-microsomal-membrane protein.	tmpzr1t_l9r_go_relaxed.owl	pyrophosphate-protein phosphotransferase activity|triphosphate:microsomal-membrane-protein phosphotransferase activity|DiPPT|pyrophosphate:protein phosphotransferase activity|diphosphate:microsomal-membrane-protein O-phosphotransferase activity|triphosphate-protein phosphotransferase activity				EC:2.7.99.1|MetaCyc:2.7.99.1-RXN									molecular_function											owl:Class	
GO:0014711	biolink:NamedThing	regulation of branchiomeric skeletal muscle development	Any process that modulates the frequency, rate or extent of branchiomeric skeletal muscle development. Branchiomeric skeletal muscle development is the process whose specific outcome is the progression of the branchiomeric skeletal muscle over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0102254	biolink:NamedThing	neoagarotetraose 1,3-alpha-3,6-anhydro-L-galactosidase activity	Catalysis of the reaction: neoagarotetraose + H2O <=> 3,6-anhydro-alpha-L-galactopyranose + agarotriose.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-12427|EC:3.2.1.159									molecular_function											owl:Class	
GO:0140199	biolink:NamedThing	negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process	Any process that stops, prevents or reduces the frequency, rate or extent of an adenylate cyclase-activating adrenergic receptor signaling pathway involved in some heart process.	tmpzr1t_l9r_go_relaxed.owl								pg	2018-02-15T19:31:23Z					biological_process											owl:Class	
GO:0033646	biolink:NamedThing	host intracellular part	Any constituent part of the living contents of a host cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	host cell intracellular part					Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.								cellular_component											owl:Class	
GO:0034979	biolink:NamedThing	NAD-dependent protein deacetylase activity	Catalysis of the removal of one or more acetyl groups from a protein, requiring NAD.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/22295			Reactome:R-HSA-9667952|Reactome:R-HSA-5688289|Reactome:R-HSA-5688294|Reactome:R-HSA-9620532|Reactome:R-HSA-5685953|Reactome:R-HSA-5211239|Reactome:R-HSA-3371467									molecular_function											owl:Class	
GO:0002693	biolink:NamedThing	positive regulation of cellular extravasation	Any process that activates or increases the frequency, rate, or extent of cellular extravasation.	tmpzr1t_l9r_go_relaxed.owl	stimulation of cellular extravasation|up-regulation of cellular extravasation|upregulation of cellular extravasation|up regulation of cellular extravasation|activation of cellular extravasation													biological_process											owl:Class	
GO:1905908	biolink:NamedThing	positive regulation of amyloid fibril formation	Any process that activates or increases the frequency, rate or extent of amyloid fibril formation.	tmpzr1t_l9r_go_relaxed.owl	activation of amyloid structure formation|positive regulation of amyloid structure formation|upregulation of amyloid fibril assembly|up regulation of amyloid fibril assembly|up-regulation of amyloid structure formation|activation of amyloid structure assembly|upregulation of amyloid fibril formation|up regulation of amyloid structure assembly|positive regulation of amyloid fibril assembly|activation of amyloid fibril formation|up regulation of amyloid fibril formation|upregulation of amyloid structure assembly|up-regulation of amyloid fibril formation|upregulation of amyloid structure formation|positive regulation of amyloid structure assembly|up-regulation of amyloid structure assembly|activation of amyloid fibril assembly|up-regulation of amyloid fibril assembly|up regulation of amyloid structure formation					Although deposition of amyloid fibrils is associated with diseases, e.g. Alzheimer's disease, amyloid formation is a normal process. Disease occurs when the balance between amyloid formation and clearance is disrupted (reviewed e.g. in PMID:29654159 and PMID:28937655). An example of a normal amyloid complex is composed of human RIP1 and RIP3 kinases  (PMID:22817896).		bc	2017-02-03T15:44:05Z					biological_process											owl:Class	
GO:0033847	biolink:NamedThing	O-phosphoserine sulfhydrylase activity	Catalysis of the reaction: O-phospho-L-serine + hydrogen sulfide = L-cysteine + phosphate.	tmpzr1t_l9r_go_relaxed.owl	O-phosphoserine(thiol)-lyase activity|O-phospho-L-serine:hydrogen-sulfide 2-amino-2-carboxyethyltransferase activity				EC:2.5.1.65|RHEA:10252|MetaCyc:2.5.1.65-RXN									molecular_function											owl:Class	
GO:2000224	biolink:NamedThing	regulation of testosterone biosynthetic process	Any process that modulates the frequency, rate or extent of testosterone biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl								yaf	2010-11-09T10:38:33Z					biological_process											owl:Class	
GO:0051311	biolink:NamedThing	meiotic metaphase plate congression	The cell cycle process in which chromosomes are aligned at the metaphase plate, a plane halfway between the poles of the meiotic spindle, during meiosis.	tmpzr1t_l9r_go_relaxed.owl	metaphase plate congression during meiosis													biological_process											owl:Class	
GO:0034275	biolink:NamedThing	kynurenic acid metabolic process	The chemical reactions and pathways involving kynurenic acid, 4-hydroxyquinoline-2-carboxylic acid.	tmpzr1t_l9r_go_relaxed.owl	4-hydroxyquinoline-2-carboxylic acid metabolic process|kynurenic acid metabolism													biological_process											owl:Class	
GO:0001803	biolink:NamedThing	regulation of type III hypersensitivity	Any process that modulates the frequency, rate, or extent of type III hypersensitivity, a type of inflammatory response.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0002883	biolink:NamedThing	regulation of hypersensitivity	Any process that modulates the frequency, rate, or extent of hypersensitivity.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1903059	biolink:NamedThing	regulation of protein lipidation	Any process that modulates the frequency, rate or extent of protein lipidation.	tmpzr1t_l9r_go_relaxed.owl	regulation of lipid:protein modification|regulation of protein amino acid lipidation							rph	2014-05-28T13:21:18Z					biological_process											owl:Class	
GO:0030196	biolink:NamedThing	cyanide hydratase activity	Catalysis of the reaction: formamide = H(2)O + hydrogen cyanide.	tmpzr1t_l9r_go_relaxed.owl	formamide hydro-lyase (cyanide-forming)|formamide dehydratase activity|formamide hydro-lyase activity				EC:4.2.1.66|KEGG_REACTION:R01408|MetaCyc:CYANIDE-HYDRATASE-RXN|RHEA:21720									molecular_function											owl:Class	
GO:0099068	biolink:NamedThing	postsynapse assembly	The aggregation, arrangement and bonding together of a set of components to form a postsynapse.	tmpzr1t_l9r_go_relaxed.owl	postsynapse biogenesis													biological_process											owl:Class	
GO:0099173	biolink:NamedThing	postsynapse organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a postsynapse.	tmpzr1t_l9r_go_relaxed.owl	postsynapse organization and biogenesis|postsynapse organisation|postsynapse development|postsynapse morphogenesis													biological_process											owl:Class	
GO:0046924	biolink:NamedThing	peptide cross-linking via 2-(S-L-cysteinyl)-L-phenylalanine	The cross-linking of a cysteine residue to an L-phenylalanine residue to form 2-(S-L-cysteinyl)-L-phenylalanine.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0340									biological_process											owl:Class	
GO:2000875	biolink:NamedThing	negative regulation of glyoxylate cycle	Any process that stops, prevents or reduces the frequency, rate or extent of glyoxylate cycle.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of glyoxylate bypass							bf	2011-07-27T01:27:15Z					biological_process											owl:Class	
GO:0033179	biolink:NamedThing	proton-transporting V-type ATPase, V0 domain	A protein complex that forms part of a proton-transporting V-type ATPase and mediates proton transport across a membrane. The V0 complex consists of at least four different subunits (a,c,d and e); six or more c subunits form a proton-binding rotor ring.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0033177	biolink:NamedThing	proton-transporting two-sector ATPase complex, proton-transporting domain	A protein complex that forms part of a proton-transporting two-sector ATPase complex and carries out proton transport across a membrane. The proton-transporting domain (F0, V0, or A0) includes integral and peripheral membrane proteins.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0043691	biolink:NamedThing	reverse cholesterol transport	The directed movement of peripheral cell cholesterol, cholest-5-en-3-beta-ol, towards the liver for catabolism.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0030301	biolink:NamedThing	cholesterol transport	The directed movement of cholesterol, cholest-5-en-3-beta-ol, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0102884	biolink:NamedThing	alpha-zingiberene synthase activity	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate <=> zingiberene + diphosphoric acid.	tmpzr1t_l9r_go_relaxed.owl					RHEA:28643|MetaCyc:RXN-8425|EC:4.2.3.65									molecular_function											owl:Class	
GO:0043664	biolink:NamedThing	host peribacteroid membrane	A host-derived membrane that surrounds one or more bacteroids (such as nitrogen-fixing bacteroids within legume root nodule cells).	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0006991	biolink:NamedThing	response to sterol depletion	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating deprivation of sterols. Sterols are a group of steroids characterized by the presence of one or more hydroxyl groups and a hydrocarbon side-chain in the molecule.	tmpzr1t_l9r_go_relaxed.owl	sterol depletion response													biological_process											owl:Class	
GO:0051111	biolink:NamedThing	peptidyl-histidine adenylylation	The adenylylation of peptidyl-histidine to form peptidyl-1'-(phospho-5'-adenosine)-L-histidine (otherwise known as tau-AMP-histidine, tele-AMP-histidine) or peptidyl-3'-(phospho-5'-adenosine)-L-histidine (otherwise known as pi-AMP-histidine, pros-AMP-histidine).	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0371									biological_process											owl:Class	
GO:1903595	biolink:NamedThing	positive regulation of histamine secretion by mast cell	Any process that activates or increases the frequency, rate or extent of histamine secretion by mast cell.	tmpzr1t_l9r_go_relaxed.owl	up regulation of histamine secretion by mast cell|up-regulation of histamine secretion by mast cell|upregulation of histamine secretion by mast cell|activation of histamine secretion by mast cell							als	2014-11-06T13:19:26Z					biological_process											owl:Class	
GO:0050729	biolink:NamedThing	positive regulation of inflammatory response	Any process that activates or increases the frequency, rate or extent of the inflammatory response.	tmpzr1t_l9r_go_relaxed.owl	upregulation of inflammatory response|stimulation of inflammatory response|up-regulation of inflammatory response|up regulation of inflammatory response|activation of inflammatory response													biological_process											owl:Class	
GO:2000949	biolink:NamedThing	negative regulation of xyloglucan metabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of xyloglucan metabolic process.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of xyloglucan metabolism							tt	2011-08-01T02:16:59Z					biological_process											owl:Class	
GO:2000948	biolink:NamedThing	regulation of xyloglucan metabolic process	Any process that modulates the frequency, rate or extent of xyloglucan metabolic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of xyloglucan metabolism							tt	2011-08-01T02:16:54Z					biological_process											owl:Class	
GO:0045907	biolink:NamedThing	positive regulation of vasoconstriction	Any process that activates or increases the frequency, rate or extent of vasoconstriction.	tmpzr1t_l9r_go_relaxed.owl	upregulation of vasoconstriction|up regulation of vasoconstriction|up-regulation of vasoconstriction|stimulation of vasoconstriction|activation of vasoconstriction													biological_process											owl:Class	
GO:0050369	biolink:NamedThing	[tyrosine 3-monooxygenase] kinase activity	Catalysis of the reaction: ATP + [tyrosine-3-monooxygenase] = ADP + phospho-[tyrosine-3-monooxygenase].	tmpzr1t_l9r_go_relaxed.owl	pheochromocytoma tyrosine hydroxylase-associated kinase activity|STK4|tyrosine 3-monooxygenase kinase activity|tyrosine 3-monooxygenase kinase (phosphorylating) activity|ATP:tyrosine-3-monoxygenase phosphotransferase activity				MetaCyc:2.7.11.6-RXN|EC:2.7.11.6|RHEA:17133									molecular_function											owl:Class	
GO:1905138	biolink:NamedThing	positive regulation of viral DNA genome packaging via site-specific sequence recognition	Any process that activates or increases the frequency, rate or extent of viral DNA genome packaging via site-specific sequence recognition.	tmpzr1t_l9r_go_relaxed.owl	up regulation of viral DNA genome packaging via site-specific sequence recognition|activation of viral DNA genome packaging via site-specific sequence recognition|up-regulation of viral DNA genome packaging via site-specific sequence recognition|upregulation of viral DNA genome packaging via site-specific sequence recognition							pr	2016-04-13T11:37:22Z					biological_process											owl:Class	
GO:1905137	biolink:NamedThing	regulation of viral DNA genome packaging via site-specific sequence recognition	Any process that modulates the frequency, rate or extent of viral DNA genome packaging via site-specific sequence recognition.	tmpzr1t_l9r_go_relaxed.owl								pr	2016-04-13T11:37:13Z					biological_process											owl:Class	
GO:0061108	biolink:NamedThing	seminal vesicle epithelium development	The progression of the seminal vesicle epithelium over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-04-30T10:19:54Z					biological_process											owl:Class	
GO:0035295	biolink:NamedThing	tube development	The process whose specific outcome is the progression of a tube over time, from its initial formation to a mature structure. Epithelial and endothelial tubes transport gases, liquids and cells from one site to another and form the basic structure of many organs and tissues including lung and trachea, kidney, the mammary gland, the vascular system and the gastrointestinal and urinary-genital tracts.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0043198	biolink:NamedThing	dendritic shaft	Cylindric portion of the dendrite, directly stemming from the perikaryon, and carrying the dendritic spines.	tmpzr1t_l9r_go_relaxed.owl	trunk				NIF_Subcellular:sao2034472720									cellular_component											owl:Class	
GO:0062037	biolink:NamedThing	D-loop DNA binding	Binding to a DNA D-loop. A D-loop is a three-stranded DNA structure formed by the invasion of a single DNA strand that base pairs with one strand of duplex DNA, while the rest of the double-stranded DNA does not unwind.	tmpzr1t_l9r_go_relaxed.owl	DNA displacement loop binding							dph	2018-04-30T15:21:21Z					molecular_function											owl:Class	
GO:0000217	biolink:NamedThing	DNA secondary structure binding	Binding to a DNA secondary structure element such as a four-way junction, a bubble, a loop, Y-form DNA, or a double-strand/single-strand junction.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1900540	biolink:NamedThing	fumonisin catabolic process	The chemical reactions and pathways resulting in the breakdown of fumonisin.	tmpzr1t_l9r_go_relaxed.owl	fumonisin degradation|fumonisin catabolism|fumonisin breakdown							tb	2012-05-11T12:54:12Z					biological_process											owl:Class	
GO:0002781	biolink:NamedThing	antifungal peptide production	The synthesis or release of an antifungal peptide during an immune response, resulting in an increase in intracellular or extracellular levels.	tmpzr1t_l9r_go_relaxed.owl						Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.								biological_process											owl:Class	
GO:0002775	biolink:NamedThing	antimicrobial peptide production	The synthesis or release of an antimicrobial peptide during an immune response, resulting in an increase in intracellular or extracellular levels. Such peptides may have protective properties against bacteria, fungi, viruses, or protozoa.	tmpzr1t_l9r_go_relaxed.owl						Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.								biological_process											owl:Class	
GO:0043887	biolink:NamedThing	melibiose:sodium symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: melibiose(out) + Na+(out) = melibiose(in) + Na+(in).	tmpzr1t_l9r_go_relaxed.owl	melibiose/Na+ symporter activity|melibiose/sodium symporter activity|Na+-melibiose symporter activity|melibiose-sodium symporter activity|thiomethylgalactoside permease II|MelB|Na+ (Li+)/melibiose symporter activity|sodium/melibiose symporter activity|Na+/melibiose symporter activity|melibiose:Na+ symporter activity|sodium:melibiose symporter activity|sodium-melibiose symporter activity|melibiose-Na+ symporter activity|Na+:melibiose symporter activity|melibiose carrier protein|melibiose permease													molecular_function											owl:Class	
GO:0015487	biolink:NamedThing	melibiose:cation symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: melibiose(out) + monovalent cation(out) = melibiose(in) + monovalent cation(in).	tmpzr1t_l9r_go_relaxed.owl	melibiose permease activity|melibiose:monovalent cation symporter activity													molecular_function											owl:Class	
GO:1900299	biolink:NamedThing	positive regulation of hexasaccharide transport	Any process that activates or increases the frequency, rate or extent of hexasaccharide transport.	tmpzr1t_l9r_go_relaxed.owl	up regulation of hexasaccharide transport|upregulation of hexasaccharide transport|up-regulation of hexasaccharide transport|activation of hexasaccharide transport							tt	2012-04-05T07:44:49Z					biological_process											owl:Class	
GO:0070638	biolink:NamedThing	pyridine nucleoside catabolic process	The chemical reactions and pathways resulting in the breakdown of any pyridine nucleoside, a nucleoside in which a pyridine base covalently bonded to a sugar, usually ribose.	tmpzr1t_l9r_go_relaxed.owl	pyridine nucleoside degradation|pyridine nucleoside breakdown|pyridine nucleoside catabolism							mah	2009-05-07T02:27:14Z					biological_process											owl:Class	
GO:0097055	biolink:NamedThing	agmatine biosynthetic process	The chemical reactions and pathways resulting in the formation of agmatine ((4-aminobutyl)guanidine, NH2-CH2-CH2-CH2-CH2-NH-C(-NH2)(=NH)). Agmatine is the decarboxylation product of the amino acid arginine and is an intermediate in polyamine biosynthesis. It is synthesized in the brain, stored in synaptic vesicles, accumulated by uptake, released by membrane depolarization, and inactivated by agmatinase.	tmpzr1t_l9r_go_relaxed.owl	agmatine synthesis|agmatine biosynthesis|agmatine formation|agmatine anabolism							pr	2011-05-25T03:56:17Z					biological_process											owl:Class	
GO:1901162	biolink:NamedThing	primary amino compound biosynthetic process	The chemical reactions and pathways resulting in the formation of primary amino compound.	tmpzr1t_l9r_go_relaxed.owl	primary amino compound anabolism|primary amino compound synthesis|primary amino compound formation|primary amino compound biosynthesis							bf	2012-07-18T04:45:14Z					biological_process											owl:Class	
GO:0044405	biolink:NamedThing	detection of host	The set of specific processes that allow an organism to detect the presence of its host via physical or chemical signals. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	recognition of host													biological_process											owl:Class	
GO:0098543	biolink:NamedThing	detection of other organism	The series of events in which a stimulus from another organism is received and converted into a molecular signal.	tmpzr1t_l9r_go_relaxed.owl	recognition of other organism involved in symbiotic interaction|recognition of other organism during symbiotic interaction	https://github.com/geneontology/go-ontology/issues/17977						dos	2013-11-11T14:28:54Z			GO:0051824		biological_process											owl:Class	
GO:0004015	biolink:NamedThing	adenosylmethionine-8-amino-7-oxononanoate transaminase activity	Catalysis of the reaction: 8-amino-7-oxononanoate + S-adenosyl-L-methionine(1+) = 7,8-diaminononanoate + S-adenosyl-4-methylthio-2-oxobutanoate.	tmpzr1t_l9r_go_relaxed.owl	7,8-diaminononanoate transaminase activity|DAPA transaminase activity|7,8-diamino-pelargonic acid aminotransferase activity|diaminopelargonate synthase activity|7-keto-8-aminopelargonic acid aminotransferase activity|7,8-diaminopelargonic acid aminotransferase activity|adenosyl methionine-8-amino-7-oxononanoate transaminase activity|adenosylmethionine-8-amino-7-oxononanoate aminotransferase activity|7-keto-8-aminopelargonic acid|adenosylmethionine--8-amino-7-oxononanoate aminotransferase activity|S-adenosyl-L-methionine:8-amino-7-oxononanoate aminotransferase activity|7,8-diaminonanoate transaminase activity|DAPA aminotransferase activity|7,8-diaminononanoate aminotransferase activity				RHEA:16861|MetaCyc:DAPASYN-RXN|KEGG_REACTION:R03231|EC:2.6.1.62									molecular_function											owl:Class	
GO:0045191	biolink:NamedThing	regulation of isotype switching	Any process that modulates the frequency, rate or extent of isotype switching.	tmpzr1t_l9r_go_relaxed.owl	regulation of class switch recombination|regulation of isotype switch recombination|regulation of class switching													biological_process											owl:Class	
GO:0050864	biolink:NamedThing	regulation of B cell activation	Any process that modulates the frequency, rate or extent of B cell activation.	tmpzr1t_l9r_go_relaxed.owl	regulation of B-lymphocyte activation|regulation of B lymphocyte activation|regulation of B-cell activation													biological_process											owl:Class	
GO:1904394	biolink:NamedThing	negative regulation of skeletal muscle acetylcholine-gated channel clustering	Any process that stops, prevents or reduces the frequency, rate or extent of skeletal muscle acetylcholine-gated channel clustering.	tmpzr1t_l9r_go_relaxed.owl	inhibition of skeletal muscle nicotinic acetylcholine receptor clustering|negative regulation of skeletal muscle AChR clustering|downregulation of skeletal muscle acetylcholine-gated channel clustering|downregulation of skeletal muscle nicotinic acetylcholine receptor clustering|down-regulation of skeletal muscle AChR clustering|down-regulation of skeletal muscle nicotinic acetylcholine receptor clustering|downregulation of skeletal muscle AChR clustering|inhibition of skeletal muscle AChR clustering|down regulation of skeletal muscle AChR clustering|down regulation of skeletal muscle acetylcholine-gated channel clustering|negative regulation of skeletal muscle nicotinic acetylcholine receptor clustering|down regulation of skeletal muscle nicotinic acetylcholine receptor clustering|down-regulation of skeletal muscle acetylcholine-gated channel clustering|inhibition of skeletal muscle acetylcholine-gated channel clustering							sl	2015-06-23T19:23:31Z					biological_process											owl:Class	
GO:0010717	biolink:NamedThing	regulation of epithelial to mesenchymal transition	Any process that modulates the rate, frequency, or extent of epithelial to mesenchymal transition. Epithelial to mesenchymal transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0071491	biolink:NamedThing	cellular response to red light	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a red light stimulus. Red light is electromagnetic radiation of wavelength of 580-700nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reversed by exposure to far red light. During the initial phase the phytochrome molecule is only present in the red light absorbing form, but on absorption of red light it changes to a far red light absorbing form, triggering progress through development. An immediate short period of exposure to far red light entirely returns the pigment to its initial state and prevents triggering of the developmental process. A thirty minute break between red and subsequent far red light exposure renders the red light effect irreversible, and development then occurs regardless of whether far red light exposure subsequently occurs.	tmpzr1t_l9r_go_relaxed.owl	cellular response to red light stimulus							mah	2009-12-18T02:19:47Z					biological_process											owl:Class	
GO:0010114	biolink:NamedThing	response to red light	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a red light stimulus. Red light is electromagnetic radiation of wavelength of 580-700nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reversed by exposure to far red light. During the initial phase the phytochrome molecule is only present in the red light absorbing form, but on absorption of red light it changes to a far red light absorbing form, triggering progress through development. An immediate short period of exposure to far red light entirely returns the pigment to its initial state and prevents triggering of the developmental process. A thirty minute break between red and subsequent far red light exposure renders the red light effect irreversible, and development then occurs regardless of whether far red light exposure subsequently occurs.	tmpzr1t_l9r_go_relaxed.owl	response to red light stimulus													biological_process											owl:Class	
GO:0010925	biolink:NamedThing	positive regulation of inositol-polyphosphate 5-phosphatase activity	Any process that increases the rate or frequency of inositol-polyphosphate 5-phosphatase activity, the catalysis of the reactions: D-myo-inositol 1,4,5-trisphosphate + H2O = myo-inositol 1,4-bisphosphate + phosphate, and 1D-myo-inositol 1,3,4,5-tetrakisphosphate + H2O = 1D-myo-inositol 1,3,4-trisphosphate + phosphate.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0019408	biolink:NamedThing	dolichol biosynthetic process	The chemical reactions and pathways resulting in the formation of dolichols, any 2,3-dihydropolyprenol derived from four or more linked isoprene units.	tmpzr1t_l9r_go_relaxed.owl	dolichol formation|dolichol anabolism|dolichol synthesis|dolichol biosynthesis													biological_process											owl:Class	
GO:0019348	biolink:NamedThing	dolichol metabolic process	The chemical reactions and pathways involving dolichols, any 2,3-dihydropolyprenol derived from four or more linked isoprene units.	tmpzr1t_l9r_go_relaxed.owl	dolichol metabolism													biological_process											owl:Class	
GO:0007026	biolink:NamedThing	negative regulation of microtubule depolymerization	Any process that stops, prevents, or reduces the frequency, rate or extent of microtubule depolymerization; prevention of depolymerization of a microtubule can result from binding by 'capping' at the plus end (e.g. by interaction with another cellular protein of structure) or by exposing microtubules to a stabilizing drug such as taxol.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of microtubule disassembly|down regulation of microtubule depolymerization|down-regulation of microtubule depolymerization|microtubule stabilization|downregulation of microtubule depolymerization|microtubule rescue|inhibition of microtubule depolymerization|negative regulation of microtubule catastrophe													biological_process											owl:Class	
GO:0102311	biolink:NamedThing	8-hydroxygeraniol dehydrogenase activity	Catalysis of the reaction: (6E)-8-hydroxygeraniol + 2 NADP <=> (6E)-8-oxogeranial + 2 NADPH + 2 H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-12961|EC:1.1.1.324|RHEA:32659									molecular_function											owl:Class	
GO:0051140	biolink:NamedThing	regulation of NK T cell proliferation	Any process that modulates the frequency, rate or extent of natural killer T cell proliferation.	tmpzr1t_l9r_go_relaxed.owl	regulation of NKT cell proliferation|regulation of NT cell proliferation|regulation of NK T-cell proliferation|regulation of NK T-lymphocyte proliferation|regulation of NK T lymphocyte proliferation|regulation of natural T cell proliferation|regulation of natural killer T cell proliferation													biological_process											owl:Class	
GO:1903216	biolink:NamedThing	regulation of protein processing involved in protein targeting to mitochondrion	Any process that modulates the frequency, rate or extent of protein processing involved in protein targeting to mitochondrion.	tmpzr1t_l9r_go_relaxed.owl	regulation of mitochondrial protein processing during import|regulation of mitochondrial processing							bf	2014-07-24T10:20:54Z					biological_process											owl:Class	
GO:1904998	biolink:NamedThing	negative regulation of leukocyte adhesion to arterial endothelial cell	Any process that stops, prevents or reduces the frequency, rate or extent of leukocyte adhesion to arterial endothelial cell.	tmpzr1t_l9r_go_relaxed.owl	down regulation of leukocyte adhesion to arterial endothelial cell|inhibition of leukocyte adhesion to arterial endothelial cell|downregulation of leukocyte adhesion to arterial endothelial cell|down-regulation of leukocyte adhesion to arterial endothelial cell							bc	2016-03-01T11:04:57Z					biological_process											owl:Class	
GO:1904995	biolink:NamedThing	negative regulation of leukocyte adhesion to vascular endothelial cell	Any process that stops, prevents or reduces the frequency, rate or extent of leukocyte adhesion to vascular endothelial cell.	tmpzr1t_l9r_go_relaxed.owl	down regulation of leukocyte adhesion to vascular endothelial cell|downregulation of leukocyte adhesion to vascular endothelial cell|inhibition of leukocyte adhesion to vascular endothelial cell|down-regulation of leukocyte adhesion to vascular endothelial cell							bc	2016-03-01T10:59:08Z					biological_process											owl:Class	
GO:1905280	biolink:NamedThing	negative regulation of retrograde transport, endosome to Golgi	Any process that stops, prevents or reduces the frequency, rate or extent of retrograde transport, endosome to Golgi.	tmpzr1t_l9r_go_relaxed.owl	downregulation of retrograde (endosome to Golgi) transport|downregulation of retrograde transport, endosome to Golgi|down regulation of retrograde transport, endosome to Golgi|down-regulation of retrograde (endosome to Golgi) transport|negative regulation of retrograde (endosome to Golgi) transport|inhibition of retrograde (endosome to Golgi) transport|inhibition of retrograde transport, endosome to Golgi|down regulation of retrograde (endosome to Golgi) transport|down-regulation of retrograde transport, endosome to Golgi							bf	2016-06-20T12:25:37Z					biological_process											owl:Class	
GO:0005247	biolink:NamedThing	voltage-gated chloride channel activity	Enables the transmembrane transfer of a chloride ion by a voltage-gated channel. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.	tmpzr1t_l9r_go_relaxed.owl	voltage-dependent chloride channel activity|voltage gated chloride channel activity				Reactome:R-HSA-2744228									molecular_function											owl:Class	
GO:0008308	biolink:NamedThing	voltage-gated anion channel activity	Enables the transmembrane transfer of an anion by a voltage-gated channel. An anion is a negatively charged ion. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.	tmpzr1t_l9r_go_relaxed.owl	voltage-gated ion-selective channel activity|voltage-dependent ion-selective channel activity				Reactome:R-HSA-9012374							GO:0022844		molecular_function											owl:Class	
GO:0031959	biolink:NamedThing	mineralocorticoid receptor signaling pathway	Any series of molecular signals generated as a consequence of a mineralocorticoid binding to its receptor.	tmpzr1t_l9r_go_relaxed.owl	mineralocorticoid receptor signalling pathway													biological_process											owl:Class	
GO:0031958	biolink:NamedThing	corticosteroid receptor signaling pathway	Any series of molecular signals generated as a consequence of a corticosteroid binding to its receptor.	tmpzr1t_l9r_go_relaxed.owl	corticosteroid receptor signalling pathway													biological_process											owl:Class	
GO:0090731	biolink:NamedThing	cellular response to very-low-density lipoprotein particle stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a very-low-density lipoprotein particle stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to VLDL particle stimulus							tb	2017-01-31T17:10:08Z					biological_process											owl:Class	
GO:0046133	biolink:NamedThing	pyrimidine ribonucleoside catabolic process	The chemical reactions and pathways resulting in the breakdown of any ribonucleoside, a nucleoside in which a pyrimidine base is linked to a ribose (beta-D-ribofuranose) molecule.	tmpzr1t_l9r_go_relaxed.owl	pyrimidine ribonucleoside degradation|pyrimidine ribonucleoside catabolism|pyrimidine ribonucleoside breakdown													biological_process											owl:Class	
GO:0046135	biolink:NamedThing	pyrimidine nucleoside catabolic process	The chemical reactions and pathways resulting in the breakdown of one of a family of organic molecules consisting of a pyrimidine base covalently bonded to a sugar ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside).	tmpzr1t_l9r_go_relaxed.owl	pyrimidine nucleoside catabolism|pyrimidine nucleoside breakdown|pyrimidine nucleoside degradation													biological_process											owl:Class	
GO:0060471	biolink:NamedThing	cortical granule exocytosis	The process of secretion by a cell that results in the release of intracellular molecules contained within a cortical granule by fusion of the vesicle with the plasma membrane of a cell. A cortical granule is a specialized secretory vesicle that is released during egg activation that changes the surface of the egg to prevent polyspermy.	tmpzr1t_l9r_go_relaxed.owl	cortical reaction|cortical granule release	https://github.com/geneontology/go-ontology/issues/13980												biological_process											owl:Class	
GO:0090559	biolink:NamedThing	regulation of membrane permeability	Any process that modulates the frequency, rate or extent of the passage or uptake of molecules by a membrane.	tmpzr1t_l9r_go_relaxed.owl								tb	2014-03-27T13:48:35Z					biological_process											owl:Class	
GO:1901791	biolink:NamedThing	3-(2,3-dihydroxyphenyl)propanoate catabolic process	The chemical reactions and pathways resulting in the breakdown of 3-(2,3-dihydroxyphenyl)propanoate.	tmpzr1t_l9r_go_relaxed.owl	3-(2,3-dihydroxyphenyl)propanoate breakdown|3-(2,3-dihydroxyphenyl)propanoate degradation|3-(2,3-dihydroxyphenyl)propanoate catabolism							yaf	2013-01-16T11:41:02Z					biological_process											owl:Class	
GO:0002449	biolink:NamedThing	lymphocyte mediated immunity	Any process involved in the carrying out of an immune response by a lymphocyte.	tmpzr1t_l9r_go_relaxed.owl	cell-mediated immunity|cellular immune response													biological_process											owl:Class	
GO:0002443	biolink:NamedThing	leukocyte mediated immunity	Any process involved in the carrying out of an immune response by a leukocyte.	tmpzr1t_l9r_go_relaxed.owl	leucocyte mediated immunity|cell-mediated immune response|cellular immune response|immune cell mediated immunity|leucocyte immune effector process|leukocyte immune effector process|immune cell effector process											GO:0019723|GO:0042087		biological_process											owl:Class	
GO:1905172	biolink:NamedThing	RISC complex binding	Binding to a RISC complex.	tmpzr1t_l9r_go_relaxed.owl	RNA-induced silencing complex binding							bf	2016-05-02T19:27:02Z					molecular_function											owl:Class	
GO:0036420	biolink:NamedThing	extrinsic component of mycolate outer membrane	The component of mycolate outer membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.	tmpzr1t_l9r_go_relaxed.owl	extrinsic to mycolate outer membrane|extrinsic to MOM|extrinsic to mycomembrane							bf	2013-09-05T20:22:02Z					cellular_component											owl:Class	
GO:0048041	biolink:NamedThing	focal adhesion assembly	The aggregation and bonding together of a set of components to form a focal adhesion, a complex of intracellular signaling and structural proteins that provides a structural link between the internal actin cytoskeleton and the ECM, and also function as a locus of signal transduction activity.	tmpzr1t_l9r_go_relaxed.owl	adhesion plaque assembly|focal adhesion formation													biological_process											owl:Class	
GO:0007044	biolink:NamedThing	cell-substrate junction assembly	The aggregation, arrangement and bonding together of a set of components to form a junction between a cell and its substrate.	tmpzr1t_l9r_go_relaxed.owl	cell-substrate adherens junction assembly					The primary label for merged term was 'cell-substrate adherens junction assembly' GO:0007045. The term was merged into the parent 'cell-substrate junction assembly', because, based on the most recent litarature, 'adherens junction' is always a 'cell-cell junction' (PMID:20571587, PMID:17854762, PMID:21422226, PMID:28096264, PMID:28401269, PMID:26923917).						GO:0007045		biological_process											owl:Class	
GO:0003830	biolink:NamedThing	beta-1,4-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity	Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + beta-D-mannosyl-R = UDP + 4-(N-acetyl-beta-D-glucosaminyl)-beta-D-mannosyl-R.	tmpzr1t_l9r_go_relaxed.owl	N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase III activity|UDP-N-acetyl-D-glucosamine:beta-D-mannosyl-glycoprotein 4-beta-N-acetyl-D-glucosaminyltransferase activity|GnTIII activity|uridine diphosphoacetylglucosamine-glycopeptide beta4-acetylglucosaminyltransferase III|beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase activity|N-acetylglucosaminyltransferase III activity|beta-1,4-mannosyl-glycoprotein beta-1,4-N-acetylglucosaminyltransferase activity|uridine diphosphoacetylglucosamine-glycopeptide beta-4-acetylglucosaminyltransferase III activity				MetaCyc:2.4.1.144-RXN|Reactome:R-HSA-975926|EC:2.4.1.144|RHEA:15509									molecular_function											owl:Class	
GO:0008375	biolink:NamedThing	acetylglucosaminyltransferase activity	Catalysis of the transfer of an N-acetylglucosaminyl residue from UDP-N-acetyl-glucosamine to a sugar.	tmpzr1t_l9r_go_relaxed.owl	GlcNAc transferase activity				Reactome:R-HSA-8879117|Reactome:R-HSA-9694656|Reactome:R-HSA-5694487|Reactome:R-HSA-9683648									molecular_function											owl:Class	
GO:0050641	biolink:NamedThing	6-methylsalicylic acid synthase activity	Catalysis of the reaction: acetyl-CoA + 3 H(+) + 3 malonyl-CoA + NADPH = 6-methylsalicylate + 3 CO(2) + 4 CoA + H(2)O + NADP(+).	tmpzr1t_l9r_go_relaxed.owl	acyl-CoA:malonyl-CoA C-acyltransferase (decarboxylating, oxoacyl-reducing, thioester-hydrolysing and cyclizing)|6-MSAS activity|MSAS activity				KEGG_REACTION:R07253|MetaCyc:2.3.1.165-RXN|EC:2.3.1.165|RHEA:12240									molecular_function											owl:Class	
GO:1901003	biolink:NamedThing	negative regulation of fermentation	Any process that stops, prevents or reduces the frequency, rate or extent of fermentation.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of fermentation|downregulation of fermentation|down regulation of fermentation|inhibition of fermentation							al	2012-06-15T08:21:31Z					biological_process											owl:Class	
GO:1901863	biolink:NamedThing	positive regulation of muscle tissue development	Any process that activates or increases the frequency, rate or extent of muscle tissue development.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of muscle tissue development|activation of muscle tissue development|up regulation of muscle tissue development|upregulation of muscle tissue development							yaf	2013-02-01T10:30:57Z					biological_process											owl:Class	
GO:0034214	biolink:NamedThing	protein hexamerization	The formation of a protein hexamer, a macromolecular structure consisting of six noncovalently associated identical or nonidentical subunits.	tmpzr1t_l9r_go_relaxed.owl	protein hexamer biosynthesis|protein hexamer formation|protein hexamer assembly|protein hexamer biosynthetic process													biological_process											owl:Class	
GO:0051259	biolink:NamedThing	protein complex oligomerization	The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of component monomers; protein oligomers may be composed of different or identical monomers. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer.	tmpzr1t_l9r_go_relaxed.owl	protein oligomer biosynthesis|protein multimerization|protein oligomer biosynthetic process|protein oligomer assembly|protein oligomer formation|protein oligomerization							bf	2011-04-05T09:57:49Z			GO:0035786		biological_process											owl:Class	
GO:0008207	biolink:NamedThing	C21-steroid hormone metabolic process	The chemical reactions and pathways involving C21-steroid hormones, steroid compounds containing 21 carbons which function as hormones.	tmpzr1t_l9r_go_relaxed.owl	C21-steroid hormone metabolism													biological_process											owl:Class	
GO:0034754	biolink:NamedThing	cellular hormone metabolic process	The chemical reactions and pathways involving any hormone, naturally occurring substances secreted by specialized cells that affects the metabolism or behavior of other cells possessing functional receptors for the hormone, as carried out by individual cells.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0030734	biolink:NamedThing	polysaccharide O-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + 1,4-N1-D-glucooligosaccharide = S-adenosyl-L-homocysteine + oligosaccharide containing 6-methyl-D-glucose units.	tmpzr1t_l9r_go_relaxed.owl	acylpolysacharide 6-methyltransferase activity|S-adenosyl-L-methionine:1,4-alpha-D-glucan 6-O-methyltransferase activity|polysaccharide methyltransferase activity				MetaCyc:POLYSACCHARIDE-O-METHYLTRANSFERASE-RXN|EC:2.1.1.18									molecular_function											owl:Class	
GO:0009691	biolink:NamedThing	cytokinin biosynthetic process	The chemical reactions and pathways resulting in the formation of cytokinins, a class of adenine-derived compounds that can function in plants as growth regulators.	tmpzr1t_l9r_go_relaxed.owl	cytokinin biosynthesis|cytokinin anabolism|cytokinin formation|cytokinin synthesis													biological_process											owl:Class	
GO:0099025	biolink:NamedThing	anchored component of postsynaptic membrane	The component of the postsynaptic membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0099144	biolink:NamedThing	anchored component of synaptic membrane	The component of the synaptic membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping.	tmpzr1t_l9r_go_relaxed.owl								dos	2017-05-25T17:25:19Z					cellular_component											owl:Class	
GO:1902973	biolink:NamedThing	mitotic DNA replication DNA ligation	Any DNA ligation involved in mitotic cell cycle DNA replication.	tmpzr1t_l9r_go_relaxed.owl	DNA ligation involved in mitotic cell cycle DNA replication|DNA ligation involved in mitotic DNA replication							jl	2014-05-06T15:20:59Z					biological_process											owl:Class	
GO:0070512	biolink:NamedThing	positive regulation of histone H4-K20 methylation	Any process that activates or increases the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 20 of histone H4.	tmpzr1t_l9r_go_relaxed.owl	up regulation of histone H4-K20 methylation|upregulation of histone H4-K20 methylation|activation of histone H4-K20 methylation|stimulation of histone H4-K20 methylation|up-regulation of histone H4-K20 methylation													biological_process											owl:Class	
GO:0031062	biolink:NamedThing	positive regulation of histone methylation	Any process that activates or increases the frequency, rate or extent of the covalent addition of methyl groups to histones.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of histone methylation|up regulation of histone methylation|upregulation of histone methylation|stimulation of histone methylation|activation of histone methylation													biological_process											owl:Class	
GO:0048340	biolink:NamedThing	paraxial mesoderm morphogenesis	The process in which the anatomical structures of the paraxial mesoderm are generated and organized.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0072175	biolink:NamedThing	epithelial tube formation	The developmental process pertaining to the initial formation of an epithelial tube.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-02-26T02:15:40Z					biological_process											owl:Class	
GO:0061457	biolink:NamedThing	mesonephric cell migration involved in male gonad development	The orderly movement of a cell from the mesonephros to the male gonad, contributing to its development.	tmpzr1t_l9r_go_relaxed.owl								dph	2012-08-22T17:31:00Z					biological_process											owl:Class	
GO:0060516	biolink:NamedThing	primary prostatic bud elongation	The increase in size of the prostatic bud as it forms.	tmpzr1t_l9r_go_relaxed.owl	prostate bud elongation involved in prostate morphogenesis|prostate bud elongation													biological_process											owl:Class	
GO:0060737	biolink:NamedThing	prostate gland morphogenetic growth	The differential increase in size or mass of the prostate gland that contributes to the gland attaining its form.	tmpzr1t_l9r_go_relaxed.owl	prostate gland growth involved in morphogenesis							dph	2009-06-15T09:24:40Z					biological_process											owl:Class	
GO:2001317	biolink:NamedThing	kojic acid biosynthetic process	The chemical reactions and pathways resulting in the formation of kojic acid.	tmpzr1t_l9r_go_relaxed.owl	kojic acid anabolism|C6H6O4 biosynthesis|C6H6O4 biosynthetic process|5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one biosynthetic process|C6H6O4 formation|C6H6O4 synthesis|C6H6O4 anabolism|kojic acid biosynthesis|5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one formation|5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one biosynthesis|kojic acid synthesis|5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one anabolism|kojic acid formation|5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one synthesis							bf	2012-04-18T09:22:46Z					biological_process											owl:Class	
GO:0034309	biolink:NamedThing	primary alcohol biosynthetic process	The chemical reactions and pathways resulting in the formation of primary alcohols. A primary alcohol is any alcohol in which a hydroxy group, -OH, is attached to a saturated carbon atom which has either three hydrogen atoms attached to it or only one other carbon atom and two hydrogen atoms attached to it.	tmpzr1t_l9r_go_relaxed.owl	primary alcohol formation|primary alcohol anabolism|primary alcohol biosynthesis|monohydric alcohol biosynthetic process|primary alcohol synthesis													biological_process											owl:Class	
GO:0031594	biolink:NamedThing	neuromuscular junction	The junction between the axon of a motor neuron and a muscle fiber. In response to the arrival of action potentials, the presynaptic button releases molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane of the muscle fiber, leading to a change in post-synaptic potential.	tmpzr1t_l9r_go_relaxed.owl	NMJ|motor endplate				Wikipedia:Neuromuscular_junction|NIF_Subcellular:sao1124888485	In vertebrates, the term 'neuromuscular junction' is limited to synapses targeting skeletal muscle fibers - all of which are  cholinergic and excitatory.  Both inhibitory and excitatory neuromuscular junctions exist in invertebrates, utilizing a range of neurotransmitters including glutamate, GABA and 5-HT.								cellular_component											owl:Class	
GO:0043302	biolink:NamedThing	positive regulation of leukocyte degranulation	Any process that activates or increases the frequency, rate or extent of leukocyte degranulation.	tmpzr1t_l9r_go_relaxed.owl	up regulation of leukocyte degranulation|up-regulation of leukocyte degranulation|stimulation of leukocyte degranulation|positive regulation of leucocyte degranulation|upregulation of leukocyte degranulation|positive regulation of immune cell degranulation|activation of leukocyte degranulation													biological_process											owl:Class	
GO:1990469	biolink:NamedThing	Rhino-Deadlock-Cutoff Complex	Protein complex found in Drosophila consisting of the gene products of cuff, del and rhi. It regulates the licensing of transcription of dual-strand PIWI interacting RNA (piRNA) source loci by binding to dual-strand-cluster chromatin, probably via the H3K9me3-binding activity of Rhi. Rhi binding brings the putative termination cofactor Cuff in close proximity to the nascent piRNA precursor transcript which it appears to protect from degradation.	tmpzr1t_l9r_go_relaxed.owl	rhi-del-cuff complex|RDC complex					An example of this is cuff in Drosophila melanogaster (Q9V629) in PMID:24906153.		bhm	2014-08-29T14:08:37Z					cellular_component											owl:Class	
GO:0046647	biolink:NamedThing	negative regulation of gamma-delta T cell proliferation	Any process that stops, prevents, or reduces the frequency, rate or extent of gamma-delta T cell proliferation.	tmpzr1t_l9r_go_relaxed.owl	inhibition of gamma-delta T cell proliferation|downregulation of gamma-delta T cell proliferation|down regulation of gamma-delta T cell proliferation|negative regulation of gamma-delta T-lymphocyte proliferation|negative regulation of gamma-delta T lymphocyte proliferation|negative regulation of gamma-delta T-cell proliferation|down-regulation of gamma-delta T cell proliferation													biological_process											owl:Class	
GO:0016877	biolink:NamedThing	ligase activity, forming carbon-sulfur bonds	Catalysis of the joining of two molecules via a carbon-sulfur bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.	tmpzr1t_l9r_go_relaxed.owl	ligase activity, forming carbon-sulphur bonds				EC:6.2.-.-									molecular_function											owl:Class	
GO:0031775	biolink:NamedThing	lutropin-choriogonadotropic hormone receptor binding	Binding to a lutropin-choriogonadotropic hormone receptor.	tmpzr1t_l9r_go_relaxed.owl	lutropin-choriogonadotropic hormone receptor ligand													molecular_function											owl:Class	
GO:0032244	biolink:NamedThing	positive regulation of nucleoside transport	Any process that activates or increases the frequency, rate or extent of the directed movement of a nucleoside into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	stimulation of nucleoside transport|activation of nucleoside transport|up regulation of nucleoside transport|up-regulation of nucleoside transport|upregulation of nucleoside transport													biological_process											owl:Class	
GO:0032241	biolink:NamedThing	positive regulation of nucleobase-containing compound transport	Any process that activates or increases the frequency, rate or extent of the directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	activation of nucleobase, nucleoside, nucleotide and nucleic acid transport|stimulation of nucleobase, nucleoside, nucleotide and nucleic acid transport|up-regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport|up regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport|positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport|upregulation of nucleobase, nucleoside, nucleotide and nucleic acid transport													biological_process											owl:Class	
GO:0009227	biolink:NamedThing	nucleotide-sugar catabolic process	The chemical reactions and pathways resulting in the breakdown of nucleotide-sugars, any nucleotide-carbohydrate in which the distal phosphoric residue of a nucleoside 5'-diphosphate is in glycosidic linkage with a monosaccharide or monosaccharide derivative.	tmpzr1t_l9r_go_relaxed.owl	nucleotide-sugar catabolism|nucleotide-sugar degradation|nucleotide-sugar breakdown													biological_process											owl:Class	
GO:0045990	biolink:NamedThing	carbon catabolite regulation of transcription	A transcription regulation process in which the presence of one carbon source leads to the modulation of the frequency, rate, or extent of transcription of specific genes involved in the metabolism of other carbon sources.	tmpzr1t_l9r_go_relaxed.owl	regulation of transcription by carbon catabolites													biological_process											owl:Class	
GO:0043096	biolink:NamedThing	purine nucleobase salvage	Any process that generates purine nucleobases, one of the two classes of nitrogen-containing ring compounds found in DNA and RNA, from derivatives of them without de novo synthesis.	tmpzr1t_l9r_go_relaxed.owl	purine base salvage													biological_process											owl:Class	
GO:0043101	biolink:NamedThing	purine-containing compound salvage	Any process that generates a purine-containing compound, any nucleobase, nucleoside, nucleotide or nucleic acid that contains a purine base, from derivatives of them without de novo synthesis.	tmpzr1t_l9r_go_relaxed.owl	purine salvage													biological_process											owl:Class	
GO:0046049	biolink:NamedThing	UMP metabolic process	The chemical reactions and pathways involving UMP, uridine monophosphate.	tmpzr1t_l9r_go_relaxed.owl	UMP metabolism													biological_process											owl:Class	
GO:0015577	biolink:NamedThing	galactitol transmembrane transporter activity	Enables the transfer of a galactitol from one side of a membrane to the other. Galactitol is the hexitol derived by the reduction of the aldehyde group of either D- or L-galactose.	tmpzr1t_l9r_go_relaxed.owl	galactitol permease activity				RHEA:33143							GO:0015588		molecular_function											owl:Class	
GO:0015166	biolink:NamedThing	polyol transmembrane transporter activity	Enables the transfer of a polyol from one side of a membrane to the other. A polyol is any polyhydric alcohol.	tmpzr1t_l9r_go_relaxed.owl	sugar/polyol channel activity				Reactome:R-HSA-429571									molecular_function											owl:Class	
GO:0051352	biolink:NamedThing	negative regulation of ligase activity	Any process that stops or reduces the rate of ligase activity, the catalysis of the ligation of two substances with concomitant breaking of a diphosphate linkage, usually in a nucleoside triphosphate.	tmpzr1t_l9r_go_relaxed.owl	inhibition of ligase activity|down regulation of ligase activity|down-regulation of ligase activity|ligase inhibitor|downregulation of ligase activity													biological_process											owl:Class	
GO:0007223	biolink:NamedThing	Wnt signaling pathway, calcium modulating pathway	The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors leads to an increase in intracellular calcium and activation of protein kinase C (PKC).	tmpzr1t_l9r_go_relaxed.owl	Wnt-activated signaling pathway, calcium modulating pathway|frizzled-2 signalling pathway|non-canonical Wnt signaling pathway|Wnt receptor signaling pathway, calcium modulating pathway|frizzled-2 signaling pathway													biological_process											owl:Class	
GO:0035567	biolink:NamedThing	non-canonical Wnt signaling pathway	The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via effectors other than beta-catenin.	tmpzr1t_l9r_go_relaxed.owl	non-canonical Wnt receptor signalling pathway|non-canonical Wnt-activated signaling pathway|non-canonical Wnt receptor signaling pathway|beta-catenin-independent Wnt receptor signaling pathway					This term should only be used when Wnt receptor signaling occurs via a beta-catenin-independent route but the downstream effectors are unknown. If the downstream effectors are known, consider instead annotating to one of the children, or requesting a new term.		bf	2010-07-23T02:26:01Z					biological_process											owl:Class	
GO:0021961	biolink:NamedThing	posterior commissure morphogenesis	Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the midbrain towards target cells in the diencephalon.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0046765	biolink:NamedThing	viral budding from nuclear membrane	A viral budding that starts with formation of a membrane curvature in the host nuclear membrane.	tmpzr1t_l9r_go_relaxed.owl	virus budding from nuclear membrane during viral capsid envelopment|virus budding from nuclear membrane by viral capsid envelopment|virus budding from nuclear membrane|viral budding from nuclear membrane by viral capsid envelopment|viral budding from nuclear membrane during viral capsid envelopment|nuclear membrane viral budding|nuclear membrane viral budding during viral capsid envelopment											GO:0046749		biological_process											owl:Class	
GO:0046755	biolink:NamedThing	viral budding	A viral process by which enveloped viruses acquire a host-derived membrane enriched in viral proteins to form their external envelope. The process starts when nucleocapsids, assembled or in the process of being built, induce formation of a membrane curvature in the host plasma or organelle membrane and wrap up in the forming bud. The process ends when the bud is eventually pinched off by membrane scission to release the enveloped particle into the lumenal or extracellular space.	tmpzr1t_l9r_go_relaxed.owl	virus budding|virion budding|viral capsid envelopment				VZ:1947							GO:0046744		biological_process											owl:Class	
GO:0010637	biolink:NamedThing	negative regulation of mitochondrial fusion	Any process that decreases the frequency, rate or extent of merging of two or more mitochondria within a cell to form a single compartment.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0102815	biolink:NamedThing	caffeoyl-CoA:delphinidin-3,5-diglucoside 5-O-glucoside-6-O-hydroxycinnamoyltransferase activity	Catalysis of the reaction: delphinidin 3-O-beta-D-glucoside-5-O-beta-D-glucoside betaine + caffeoyl-CoA <=> delphinidin 3-O-glucosyl-5-O-caffeoylglucoside + coenzyme A.	tmpzr1t_l9r_go_relaxed.owl					EC:2.3.1.153|MetaCyc:RXN-8233									molecular_function											owl:Class	
GO:0070479	biolink:NamedThing	nuclear-transcribed mRNA catabolic process, 5'-3' exonucleolytic nonsense-mediated decay	The chemical reactions and pathways resulting in the breakdown of the nuclear-transcribed mRNA transcript body of an mRNA in which an amino-acid codon has changed to a nonsense codon; occurs when the 5' end is not protected by a 5'-cap; degradation proceeds in the 5' to 3' direction.	tmpzr1t_l9r_go_relaxed.owl	5'-3' nonsense-mediated decay|nuclear-transcribed mRNA catabolism, 5'-3' exonucleolytic nonsense-mediated decay|nuclear-transcribed mRNA breakdown, 5'-3' exonucleolytic nonsense-mediated decay|5'-3' nonsense-mediated mRNA decay|5'-3' NMD|nuclear-transcribed mRNA degradation, 5'-3' exonucleolytic nonsense-mediated decay													biological_process											owl:Class	
GO:0000184	biolink:NamedThing	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	The nonsense-mediated decay pathway for nuclear-transcribed mRNAs degrades mRNAs in which an amino-acid codon has changed to a nonsense codon; this prevents the translation of such mRNAs into truncated, and potentially harmful, proteins.	tmpzr1t_l9r_go_relaxed.owl	mRNA catabolic process, nonsense-mediated|nuclear mRNA catabolic process, nonsense-mediated decay|mRNA breakdown, nonsense-mediated decay|mRNA degradation, nonsense-mediated decay|mRNA catabolism, nonsense-mediated|nonsense-mediated mRNA decay				Wikipedia:Nonsense-mediated_mRNA_decay|Wikipedia:Nonsense-mediated_decay									biological_process											owl:Class	
GO:0060885	biolink:NamedThing	clearance of cells from fusion plate by apoptotic process	Any apoptotic process that contributes to the shaping of the semicircular canal by removing cells in the fusion plate, forming the loops of the canals.	tmpzr1t_l9r_go_relaxed.owl	clearance of cells from fusion plate by apoptosis							dph	2009-08-13T12:30:17Z					biological_process											owl:Class	
GO:0050228	biolink:NamedThing	pterin deaminase activity	Catalysis of the reaction: 2-amino-4-hydroxypteridine + H2O = 2,4-dihydroxypteridine + NH3.	tmpzr1t_l9r_go_relaxed.owl	acrasinase activity|2-amino-4-hydroxypteridine aminohydrolase activity				MetaCyc:PTERIN-DEAMINASE-RXN|EC:3.5.4.11|RHEA:11904									molecular_function											owl:Class	
GO:0010095	biolink:NamedThing	specification of petal identity	The process in which a floral organ primordium acquires petal identity. Identity is considered to be the aggregate of characteristics by which a structure is recognized.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0010093	biolink:NamedThing	specification of floral organ identity	The process in which the identity of a floral organ primordium is specified. Identity is considered to be the aggregate of characteristics by which a structure is recognized.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0070288	biolink:NamedThing	ferritin complex	A protein complex that binds iron and acts as a major iron storage system. Intracellular and extracellular ferritin complexes have different ratios of two types of ferritin monomer, the L (light) chain and H (heavy) chain.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0050772	biolink:NamedThing	positive regulation of axonogenesis	Any process that activates or increases the frequency, rate or extent of axonogenesis.	tmpzr1t_l9r_go_relaxed.owl	up regulation of axonogenesis|upregulation of axonogenesis|up-regulation of axonogenesis|stimulation of axonogenesis|activation of axonogenesis													biological_process											owl:Class	
GO:0098945	biolink:NamedThing	intrinsic component of presynaptic active zone membrane	The component of the presynaptic active zone membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.	tmpzr1t_l9r_go_relaxed.owl	intrinsic to presynaptic acive zone membrane													cellular_component											owl:Class	
GO:0030927	biolink:NamedThing	manganese incorporation into metallo-oxygen cluster via bis-L-aspartato tris-L-glutamato L-histidino calcium tetramanganese tetroxide	The incorporation of manganese into a 4Mn-Ca-4O complex by bis-L-aspartato tris-L-glutamato L-histidino calcium tetramanganese tetroxide as in the photosystem II catalytic site.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0366									biological_process											owl:Class	
GO:0030924	biolink:NamedThing	manganese incorporation into metallo-oxygen cluster	The incorporation of manganese into a metallo-oxygen cluster.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1900960	biolink:NamedThing	negative regulation of 17-methylnonadec-1-ene metabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of 17-methylnonadec-1-ene metabolic process.	tmpzr1t_l9r_go_relaxed.owl	down regulation of 17-methylnonadec-1-ene metabolic process|down-regulation of 17-methylnonadec-1-ene metabolism|down regulation of 17-methylnonadec-1-ene metabolism|downregulation of 17-methylnonadec-1-ene metabolic process|down-regulation of 17-methylnonadec-1-ene metabolic process|negative regulation of 17-methylnonadec-1-ene metabolism|inhibition of 17-methylnonadec-1-ene metabolic process|inhibition of 17-methylnonadec-1-ene metabolism|downregulation of 17-methylnonadec-1-ene metabolism							tt	2012-06-14T03:29:51Z					biological_process											owl:Class	
GO:0021755	biolink:NamedThing	eurydendroid cell differentiation	The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature eurydendroid cell. Differentiation includes the processes involved in commitment of a neuroblast to a eurydendroid cell fate. A eurydendroid cell is an efferent neuron found in the cerebellar cortex of teleosts.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0007557	biolink:NamedThing	regulation of juvenile hormone biosynthetic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of juvenile hormone.	tmpzr1t_l9r_go_relaxed.owl	regulation of juvenile hormone synthesis|regulation of juvenile hormone anabolism|regulation of juvenile hormone formation|regulation of juvenile hormone biosynthesis													biological_process											owl:Class	
GO:0031017	biolink:NamedThing	exocrine pancreas development	The process whose specific outcome is the progression of the exocrine pancreas over time, from its formation to the mature structure. The exocrine pancreas produces and store zymogens of digestive enzymes, such as chymotrypsinogen and trypsinogen in the acinar cells.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0090614	biolink:NamedThing	5'-methylthioadenosine deaminase activity	Catalysis of the reaction: 5'methyl thioadenosine + H2O = 5'methyl thioinosine + NH3.	tmpzr1t_l9r_go_relaxed.owl					EC:3.5.4.31|RHEA:25025			tb	2014-10-23T15:59:38Z					molecular_function											owl:Class	
GO:0090627	biolink:NamedThing	plant epidermal cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a plant epidermal cell.	tmpzr1t_l9r_go_relaxed.owl								tb	2015-02-05T14:23:28Z					biological_process											owl:Class	
GO:1902748	biolink:NamedThing	positive regulation of lens fiber cell differentiation	Any process that activates or increases the frequency, rate or extent of lens fiber cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of lens fibre cell differentiation|activation of lens fiber cell differentiation|upregulation of lens fiber cell differentiation|activation of lens fibre cell differentiation|up-regulation of lens fiber cell differentiation|up regulation of lens fibre cell differentiation|up-regulation of lens fibre cell differentiation|up regulation of lens fiber cell differentiation|upregulation of lens fibre cell differentiation							mr	2014-03-03T23:20:12Z					biological_process											owl:Class	
GO:1904570	biolink:NamedThing	negative regulation of selenocysteine incorporation	Any process that stops, prevents or reduces the frequency, rate or extent of selenocysteine incorporation.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of selenocysteine incorporation|down regulation of selenocysteine incorporation|downregulation of selenocysteine incorporation|inhibition of selenocysteine incorporation							sl	2015-08-19T17:26:44Z					biological_process											owl:Class	
GO:0045900	biolink:NamedThing	negative regulation of translational elongation	Any process that stops, prevents, or reduces the frequency, rate or extent of translational elongation.	tmpzr1t_l9r_go_relaxed.owl	downregulation of translational elongation|inhibition of translational elongation|down-regulation of translational elongation|down regulation of translational elongation													biological_process											owl:Class	
GO:0018672	biolink:NamedThing	anthranilate 3-monooxygenase (deaminating) activity	Catalysis of the reaction: anthranilate + 2 H(+) + NADPH + O(2) = 2,3-dihydroxybenzoate + NADP(+) + NH(4)(+).	tmpzr1t_l9r_go_relaxed.owl	anthranilate 2,3-dioxygenase (deaminating)|anthranilate hydroxylase activity|anthranilate 2,3-hydroxylase (deaminating) activity|anthranilate,NADPH:oxygen oxidoreductase (3-hydroxylating, deaminating)|anthranilate hydroxylase (deaminating) activity				RHEA:21236|KEGG_REACTION:R00980|EC:1.14.13.35|MetaCyc:1.14.13.35-RXN|UM-BBD_reactionID:r0578									molecular_function											owl:Class	
GO:0042166	biolink:NamedThing	acetylcholine binding	Binding to acetylcholine, an acetic acid ester of the organic base choline that functions as a neurotransmitter, released at the synapses of parasympathetic nerves and at neuromuscular junctions.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0000288	biolink:NamedThing	nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	A major pathway of degradation of nuclear-transcribed mRNAs that proceeds through a series of ordered steps that includes poly(A) tail shortening and that can regulate mRNA stability.	tmpzr1t_l9r_go_relaxed.owl	mRNA breakdown, deadenylation-dependent decay|mRNA degradation, deadenylation-dependent decay|deadenylation-dependent mRNA decay|nuclear mRNA catabolic process, deadenylation-dependent decay|mRNA catabolic process, deadenylylation-dependent|mRNA catabolic process, deadenylation-dependent|mRNA catabolism, deadenylation-dependent|mRNA catabolism, deadenylylation-dependent	https://github.com/geneontology/go-ontology/issues/20568												biological_process											owl:Class	
GO:0048866	biolink:NamedThing	stem cell fate specification	The process in which a cell becomes capable of differentiating autonomously into a stem cell in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0001708	biolink:NamedThing	cell fate specification	The process involved in the specification of cell identity. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0010062	biolink:NamedThing	negative regulation of trichoblast fate specification	Any process that suppresses trichoblast fate specification.	tmpzr1t_l9r_go_relaxed.owl	inhibition of trichoblast fate|down regulation of trichoblast fate|downregulation of trichoblast fate|down-regulation of trichoblast fate													biological_process											owl:Class	
GO:1903889	biolink:NamedThing	negative regulation of plant epidermal cell differentiation	Any process that stops, prevents or reduces the frequency, rate or extent of plant epidermal cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	down regulation of plant epidermal cell differentiation|down-regulation of plant epidermal cell differentiation|inhibition of plant epidermal cell differentiation|downregulation of plant epidermal cell differentiation							tb	2015-02-06T22:29:52Z					biological_process											owl:Class	
GO:1900799	biolink:NamedThing	cordyol C biosynthetic process	The chemical reactions and pathways resulting in the formation of cordyol C.	tmpzr1t_l9r_go_relaxed.owl	cordyol C synthesis|cordyol C formation|cordyol C biosynthesis|cordyol C anabolism							di	2012-06-04T09:48:17Z					biological_process											owl:Class	
GO:1903555	biolink:NamedThing	regulation of tumor necrosis factor superfamily cytokine production	Any process that modulates the frequency, rate or extent of tumor necrosis factor superfamily cytokine production.	tmpzr1t_l9r_go_relaxed.owl	regulation of TNFSF cytokine production|regulation of TNF superfamily production							pga	2014-10-21T10:26:05Z					biological_process											owl:Class	
GO:1900990	biolink:NamedThing	scopolamine catabolic process	The chemical reactions and pathways resulting in the breakdown of scopolamine.	tmpzr1t_l9r_go_relaxed.owl	scopolamine degradation|scopolamine catabolism|scopolamine breakdown							yaf	2012-06-14T09:48:00Z					biological_process											owl:Class	
GO:1904781	biolink:NamedThing	positive regulation of protein localization to centrosome	Any process that activates or increases the frequency, rate or extent of protein localization to centrosome.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of protein localization to centrosome|activation of protein localisation to centrosome|up-regulation of protein localisation to centrosome|upregulation of protein localisation to centrosome|up regulation of protein localization to centrosome|upregulation of protein localization to centrosome|up regulation of protein localisation to centrosome|positive regulation of protein localisation to centrosome|activation of protein localization to centrosome					An example is cdk-2 in C. elegans (UniProt ID O61847) in PMID:17115027 (inferred from mutant phenotype).		es	2015-10-30T11:54:53Z					biological_process											owl:Class	
GO:0046639	biolink:NamedThing	negative regulation of alpha-beta T cell differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of alpha-beta T cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	downregulation of alpha-beta T cell differentiation|negative regulation of alpha-beta T lymphocyte differentiation|negative regulation of alpha-beta T cell development|negative regulation of alpha-beta T-cell differentiation|inhibition of alpha-beta T cell differentiation|down regulation of alpha-beta T cell differentiation|down-regulation of alpha-beta T cell differentiation|negative regulation of alpha-beta T-lymphocyte differentiation					Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.								biological_process											owl:Class	
GO:0045581	biolink:NamedThing	negative regulation of T cell differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of T cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of T cell development|down regulation of T cell differentiation|negative regulation of T-cell differentiation|negative regulation of T lymphocyte differentiation|negative regulation of T-lymphocyte differentiation|down-regulation of T cell differentiation|downregulation of T cell differentiation|inhibition of T cell differentiation					Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.								biological_process											owl:Class	
GO:0098708	biolink:NamedThing	glucose import across plasma membrane	The directed movement of glucose from outside of a cell, across the plasma membrane and into the cytosol.	tmpzr1t_l9r_go_relaxed.owl	glucose import into cell|high affinity glucose import							al	2012-12-06T14:54:07Z			GO:0061490|GO:1990821		biological_process											owl:Class	
GO:0140271	biolink:NamedThing	hexose import across plasma membrane	The directed movement of hexose from outside of a cell, across the plasma membrane and into the cytosol.	tmpzr1t_l9r_go_relaxed.owl								pg	2018-10-01T08:49:49Z					biological_process											owl:Class	
GO:0098799	biolink:NamedThing	outer mitochondrial membrane protein complex	Any protein complex that is part of the outer mitochondrial membrane.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0140216	biolink:NamedThing	negative regulation of D-aspartate import across plasma membrane	Any process that stops, prevents or reduces the frequency, rate or extent of the directed import of D-aspartate from the extracellular region across the plasma membrane and into the cytosol.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/15041						pg	2018-04-11T15:43:25Z					biological_process											owl:Class	
GO:0140060	biolink:NamedThing	axon arborization	The process in which the terminal anatomical structures of an axon are generated and organized into branches of specialised projections, or boutons. An axon is the long process of a neuron that conducts nerve impulses, usually away from the cell body to the terminal branches.	tmpzr1t_l9r_go_relaxed.owl								pg	2017-07-12T15:17:22Z					biological_process											owl:Class	
GO:0140058	biolink:NamedThing	neuron projection arborization	The process in which the anatomical structures of a neuron projection are generated and organized into branches. A neuron projection is any process extending from a neural cell, such as axons or dendrites.	tmpzr1t_l9r_go_relaxed.owl	branching morphogenesis of a neuron projection|neuron projection branching|neurite branching|neurite arborization|branching morphogenesis of a neurite							pg	2017-07-12T12:25:31Z					biological_process											owl:Class	
GO:0016891	biolink:NamedThing	endoribonuclease activity, producing 5'-phosphomonoesters	Catalysis of the hydrolysis of ester linkages within ribonucleic acids by creating internal breaks to yield 5'-phosphomonoesters.	tmpzr1t_l9r_go_relaxed.owl					EC:3.1.26.-									molecular_function											owl:Class	
GO:0016893	biolink:NamedThing	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	Catalysis of the hydrolysis of ester linkages within nucleic acids by creating internal breaks to yield 5'-phosphomonoesters.	tmpzr1t_l9r_go_relaxed.owl	endoribonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters|5'-endonuclease activity				EC:3.1.30.-	Note that this activity can catalyze cleavage of DNA or RNA.								molecular_function											owl:Class	
GO:0070927	biolink:NamedThing	negative regulation of ATP:ADP antiporter activity	Any process that stops or reduces the activity of an ATP:ADP antiporter.	tmpzr1t_l9r_go_relaxed.owl	downregulation of ATP:ADP antiporter activity|inhibition of ATP:ADP antiporter activity|down-regulation of ATP:ADP antiporter activity|down regulation of ATP:ADP antiporter activity							mah	2009-09-16T02:58:02Z					biological_process											owl:Class	
GO:0070926	biolink:NamedThing	regulation of ATP:ADP antiporter activity	Any process that modulates the activity of an ATP:ADP antiporter.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-09-16T02:56:35Z					biological_process											owl:Class	
GO:0031984	biolink:NamedThing	organelle subcompartment	A compartment that consists of a lumen and an enclosing membrane, and is part of an organelle.	tmpzr1t_l9r_go_relaxed.owl	suborganelle compartment					Note that this term refers to membrane-bounded compartments that are not considered organelles in their own right, but form parts of larger organelles.								cellular_component											owl:Class	
GO:0031406	biolink:NamedThing	carboxylic acid binding	Binding to a carboxylic acid, an organic acid containing one or more carboxyl (COOH) groups or anions (COO-).	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1903571	biolink:NamedThing	negative regulation of protein kinase D signaling	Any process that stops, prevents or reduces the frequency, rate or extent of protein kinase D signaling.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of protein kinase D signaling cascade|down regulation of PKD signaling cascade|negative regulation of PKD signal transduction|inhibition of protein kinase D signaling cascade|inhibition of PKD signal transduction|downregulation of protein kinase D signal transduction|inhibition of protein kinase D signal transduction|downregulation of protein kinase D signaling cascade|negative regulation of protein kinase D signalling cascade|down-regulation of protein kinase D signal transduction|downregulation of PKD signaling cascade|downregulation of protein kinase D signaling|down-regulation of PKD signaling cascade|down regulation of PKD signal transduction|down-regulation of protein kinase D signaling cascade|down regulation of protein kinase D signalling cascade|downregulation of PKD signal transduction|down-regulation of PKD signal transduction|inhibition of PKD signaling cascade|down regulation of protein kinase D signaling cascade|negative regulation of PKD signaling cascade|down-regulation of protein kinase D signalling cascade|down regulation of protein kinase D signaling|down-regulation of protein kinase D signaling|downregulation of protein kinase D signalling cascade|inhibition of protein kinase D signalling cascade|down regulation of protein kinase D signal transduction|negative regulation of protein kinase D signal transduction|inhibition of protein kinase D signaling							rl	2014-10-27T15:18:10Z					biological_process											owl:Class	
GO:0046045	biolink:NamedThing	TMP catabolic process	The chemical reactions and pathways resulting in the breakdown of TMP, ribosylthymine monophosphate.	tmpzr1t_l9r_go_relaxed.owl	TMP breakdown|TMP degradation|TMP catabolism													biological_process											owl:Class	
GO:0046044	biolink:NamedThing	TMP metabolic process	The chemical reactions and pathways involving TMP, ribosylthymine monophosphate.	tmpzr1t_l9r_go_relaxed.owl	TMP metabolism													biological_process											owl:Class	
GO:0099616	biolink:NamedThing	extrinsic component of matrix side of mitochondrial inner membrane	The component of the matrix side of the mitochondrial inner membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0019775	biolink:NamedThing	FAT10 transferase activity	Catalysis of the transfer of FAT10 from one protein to another via the reaction X-FAT10 + Y --> Y-FAT10 + X, where both X-FAT10 and Y-FAT10 are covalent linkages.	tmpzr1t_l9r_go_relaxed.owl	FAT10 conjugating enzyme activity													molecular_function											owl:Class	
GO:0032480	biolink:NamedThing	negative regulation of type I interferon production	Any process that stops, prevents, or reduces the frequency, rate, or extent of type I interferon production. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families.	tmpzr1t_l9r_go_relaxed.owl	inhibition of type I interferon production|down regulation of type I interferon production|downregulation of type I interferon production|negative regulation of type I IFN production|down-regulation of type I interferon production													biological_process											owl:Class	
GO:1902425	biolink:NamedThing	positive regulation of attachment of mitotic spindle microtubules to kinetochore	Any process that activates or increases the frequency, rate or extent of attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation.	tmpzr1t_l9r_go_relaxed.owl	activation of attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation|up-regulation of attachment of spindle microtubules to kinetochore during mitosis|up regulation of attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation|upregulation of attachment of spindle microtubules to kinetochore during mitosis|upregulation of attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation|positive regulation of attachment of spindle microtubules to kinetochore during mitosis|positive regulation of mitotic bipolar attachment|up regulation of attachment of spindle microtubules to kinetochore during mitosis|up regulation of attachment of spindle microtubules to mitotic chromosome|up-regulation of mitotic bipolar attachment|upregulation of attachment of spindle microtubules to mitotic chromosome|positive regulation of attachment of spindle microtubules to mitotic chromosome|activation of attachment of spindle microtubules to kinetochore during mitosis|activation of attachment of spindle microtubules to mitotic chromosome|positive regulation of attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation|activation of attachment of spindle microtubules to kinetochore involved in mitosis|upregulation of attachment of spindle microtubules to kinetochore involved in mitosis|positive regulation of attachment of spindle microtubules to kinetochore involved in mitosis|up-regulation of attachment of spindle microtubules to kinetochore involved in mitosis|activation of mitotic bipolar attachment|up-regulation of attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation|up-regulation of attachment of spindle microtubules to mitotic chromosome|up regulation of attachment of spindle microtubules to kinetochore involved in mitosis|up regulation of mitotic bipolar attachment|upregulation of mitotic bipolar attachment							vw	2013-09-19T10:33:55Z					biological_process											owl:Class	
GO:0051987	biolink:NamedThing	positive regulation of attachment of spindle microtubules to kinetochore	Any process that activates or increases the frequency, rate or extent of the attachment of spindle microtubules to the kinetochore.	tmpzr1t_l9r_go_relaxed.owl	upregulation of attachment of spindle microtubules to kinetochore|up-regulation of attachment of spindle microtubules to kinetochore|stimulation of attachment of spindle microtubules to kinetochore|up regulation of attachment of spindle microtubules to kinetochore|activation of attachment of spindle microtubules to kinetochore													biological_process											owl:Class	
GO:0042415	biolink:NamedThing	norepinephrine metabolic process	The chemical reactions and pathways involving norepinephrine, a hormone secreted by the adrenal medulla, and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts in the central nervous system. It is also the demethylated biosynthetic precursor of epinephrine.	tmpzr1t_l9r_go_relaxed.owl	levarterenol metabolism|noradrenaline metabolism|noradrenaline metabolic process|levarterenol metabolic process|norepinephrine metabolism													biological_process											owl:Class	
GO:0006584	biolink:NamedThing	catecholamine metabolic process	The chemical reactions and pathways involving any of a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine.	tmpzr1t_l9r_go_relaxed.owl	catecholamine metabolism													biological_process											owl:Class	
GO:1902801	biolink:NamedThing	regulation of siRNA-independent facultative heterochromatin assembly	Any process that modulates the frequency, rate or extent of siRNA-independent facultative heterochromatin assembly.	tmpzr1t_l9r_go_relaxed.owl	regulation of heterochromatin island formation|regulation of heterochromatin island assembly	https://github.com/geneontology/go-ontology/issues/22326						mah	2014-03-25T14:44:48Z					biological_process											owl:Class	
GO:1902898	biolink:NamedThing	fatty acid methyl ester metabolic process	The chemical reactions and pathways involving fatty acid methyl ester.	tmpzr1t_l9r_go_relaxed.owl	fatty acid methyl ester metabolism|FAME metabolic process							tt	2014-04-11T03:08:34Z					biological_process											owl:Class	
GO:0098863	biolink:NamedThing	nuclear migration by microtubule mediated pushing forces	The directed movement of the nucleus by pushing forces exerted by polymerization of backward-extending microtubules.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0032736	biolink:NamedThing	positive regulation of interleukin-13 production	Any process that activates or increases the frequency, rate, or extent of interleukin-13 production.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of interleukin-13 secretion|upregulation of interleukin-13 production|up regulation of interleukin-13 production|up-regulation of interleukin-13 production|activation of interleukin-13 production|stimulation of interleukin-13 production|positive regulation of IL-13 production|positive regulation of interleukin-13 biosynthetic process											GO:0045368|GO:2000667		biological_process											owl:Class	
GO:0052883	biolink:NamedThing	tyrosine ammonia-lyase activity	Catalysis of the reaction: L-tyrosine = NH(4)(+) + trans-4-coumarate.	tmpzr1t_l9r_go_relaxed.owl	L-tyrosine ammonia-lyase activity|TAL activity|tyrase activity				EC:4.3.1.23|EC:4.3.1.25|RHEA:24906									molecular_function											owl:Class	
GO:0072324	biolink:NamedThing	ascus epiplasm	Ascus cytoplasm that is not packaged into ascospores.	tmpzr1t_l9r_go_relaxed.owl						Note that this term is an is_a child of 'cell part' because the epiplasm is extracellular to the spore (each of which is a cell) but within the ascus structure, and originated from cytoplasm.		mah	2010-10-28T04:37:46Z					cellular_component											owl:Class	
GO:0075253	biolink:NamedThing	positive regulation of uredospore formation	Any process that activates, maintains or increases the frequency, rate or extent of uredospore formation, a process in which an asexual, dikaryotic, often rusty-colored spore, is formed in a structure called a uredinium.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of ureidospore formation													biological_process											owl:Class	
GO:0071994	biolink:NamedThing	phytochelatin transmembrane transport	The process in which a phytochelatin is transported across a membrane. Phytochelatins are a group of peptides that bind metals (Cd, Zn, Cu, Pb, Hg) in thiolate coordination complexes.	tmpzr1t_l9r_go_relaxed.owl	phytochelatin membrane transport|cadystin transmembrane transport					Note that this term is not intended for use in annotating lateral movement within membranes.		mah	2010-10-25T01:58:50Z					biological_process											owl:Class	
GO:0071993	biolink:NamedThing	phytochelatin transport	The directed movement of a phytochelatin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Phytochelatins are a group of peptides that bind metals (Cd, Zn, Cu, Pb, Hg) in thiolate coordination complexes.	tmpzr1t_l9r_go_relaxed.owl	cadystin transport							mah	2010-10-25T01:57:55Z					biological_process											owl:Class	
GO:0015883	biolink:NamedThing	FAD transport	The directed movement of flavin-adenine dinucleotide (FAD) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. FAD forms the coenzyme of the prosthetic group of various flavoprotein oxidoreductase enzymes, in which it functions as an electron acceptor by being reversibly converted to its reduced form.	tmpzr1t_l9r_go_relaxed.owl	flavin adenine dinucleotide transport|flavin-adenine dinucleotide transport													biological_process											owl:Class	
GO:0045132	biolink:NamedThing	meiotic chromosome segregation	The process in which genetic material, in the form of chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets during M phase of the meiotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0010852	biolink:NamedThing	cyclase inhibitor activity	Decreases the activity of an enzyme that catalyzes a ring closure reaction.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0002445	biolink:NamedThing	type II hypersensitivity	An inflammatory response resulting in cell death or dysfunction mediated by activation of the classical complement pathway or induction of effector cell phagocytosis, cytolysis mechanisms via complement or Fc receptors following the binding of antibodies to cell surface antigens on a target cell, or mediated by the direct binding of antibody to cellular receptors.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Type_II_hypersensitivity									biological_process											owl:Class	
GO:0016064	biolink:NamedThing	immunoglobulin mediated immune response	An immune response mediated by immunoglobulins, whether cell-bound or in solution.	tmpzr1t_l9r_go_relaxed.owl	antibody-mediated immune response													biological_process											owl:Class	
GO:0032416	biolink:NamedThing	negative regulation of sodium:proton antiporter activity	Any process that stops or reduces the activity of a sodium:hydrogen antiporter, which catalyzes the reaction: Na+(out) + H+(in) = Na+(in) + H+(out).	tmpzr1t_l9r_go_relaxed.owl	downregulation of sodium:hydrogen antiporter activity|inhibition of sodium:hydrogen antiporter activity|negative regulation of sodium:hydrogen antiporter activity|down regulation of sodium:hydrogen antiporter activity|down-regulation of sodium:hydrogen antiporter activity													biological_process											owl:Class	
GO:2000650	biolink:NamedThing	negative regulation of sodium ion transmembrane transporter activity	Any process that stops, prevents or reduces the frequency, rate or extent of sodium ion transmembrane transporter activity.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of sodium transporter activity							yaf	2011-04-28T08:42:57Z					biological_process											owl:Class	
GO:0110162	biolink:NamedThing	regulation of mitotic spindle elongation (spindle phase three)	Any process that modulates the frequency, rate or extent of the cell cycle process in which the distance is lengthened between poles of the mitotic spindle during mitotic prophase (spindle phase three).	tmpzr1t_l9r_go_relaxed.owl								kmv	2019-08-12T15:26:01Z					biological_process											owl:Class	
GO:0009882	biolink:NamedThing	blue light photoreceptor activity	The function of absorbing and responding to electromagnetic radiation with a wavelength of approximately 400-470nm. The response may involve a change in conformation.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0009881	biolink:NamedThing	photoreceptor activity	The function of absorbing and responding to incidental electromagnetic radiation, particularly visible light. The response may involve a change in conformation.	tmpzr1t_l9r_go_relaxed.owl	UV-sensitive opsin|opsin|long-wave-sensitive opsin|blue-sensitive opsin|short-wave-sensitive opsin|violet-sensitive opsin|red-sensitive opsin|green-sensitive opsin													molecular_function											owl:Class	
GO:1903697	biolink:NamedThing	negative regulation of microvillus assembly	Any process that stops, prevents or reduces the frequency, rate or extent of microvillus assembly.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of microvillus assembly|down-regulation of microvillus biogenesis|down regulation of microvillus biogenesis|down regulation of microvillus assembly|downregulation of microvillus assembly|inhibition of microvillus biogenesis|negative regulation of microvillus biogenesis|downregulation of microvillus biogenesis|inhibition of microvillus assembly							als	2014-12-03T11:45:08Z					biological_process											owl:Class	
GO:0120033	biolink:NamedThing	negative regulation of plasma membrane bounded cell projection assembly	Any process that stops, prevents or reduces the frequency, rate or extent of plasma membrane bounded cell projection assembly.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/13298						krc	2017-04-26T04:34:31Z					biological_process											owl:Class	
GO:0007206	biolink:NamedThing	phospholipase C-activating G protein-coupled glutamate receptor signaling pathway	The series of molecular signals generated as a consequence of a G protein-coupled glutamate receptor binding to its physiological ligand, where the pathway proceeds with activation of phospholipase C (PLC) and a subsequent release of inositol trisphosphate (IP3) and diacylglycerol (DAG).	tmpzr1t_l9r_go_relaxed.owl	activation of phospholipase C activity by metabotropic glutamate receptor signaling pathway|activation of phospholipase C activity by G-protein coupled glutamate receptor signaling pathway|metabotropic glutamate receptor, phospholipase C activating pathway|activation of phospholipase C activity by metabotropic glutamate receptor signalling pathway|phospholipase C-activating G-protein coupled glutamate receptor signaling pathway													biological_process											owl:Class	
GO:0007216	biolink:NamedThing	G protein-coupled glutamate receptor signaling pathway	A series of molecular signals initiated by glutamate binding to a glutamate receptor on the surface of the target cell, and proceeding with the activated receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. Ends with regulation of a downstream cellular process, e.g. transcription.	tmpzr1t_l9r_go_relaxed.owl	metabotropic glutamate receptor signalling pathway|metabotropic glutamate receptor signaling pathway|G-protein coupled glutamate receptor signaling pathway													biological_process											owl:Class	
GO:0043035	biolink:NamedThing	chromatin insulator sequence binding	Interacting selectively and non-covalently and stoichiometrically with a chromatin insulator sequence, a DNA sequence that prevents enhancer-mediated activation or repression of transcription.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0031490	biolink:NamedThing	chromatin DNA binding	Binding to DNA that is assembled into chromatin.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0010449	biolink:NamedThing	root meristem growth	The increase in size or mass of a root meristem, a population of undifferentiated cells in a plant root which maintains a continuous balance between the production of stem cells and the incorporation of their derivatives into the growth of the root.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0035266	biolink:NamedThing	meristem growth	The increase in size or mass of a meristem, a region of tissue in a plant that is composed of one or more undifferentiated cells capable of undergoing mitosis and differentiation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0004655	biolink:NamedThing	porphobilinogen synthase activity	Catalysis of the reaction: 2 5-aminolevulinate = 2 H(2)O + H(+) + porphobilinogen.	tmpzr1t_l9r_go_relaxed.owl	delta-aminolevulinic acid dehydratase activity|5-aminolevulinate hydro-lyase (adding 5-aminolevulinate and cyclizing)|aminolevulinate dehydratase activity|5-levulinic acid dehydratase activity|delta-aminolevulinic dehydratase activity|5-aminolevulinate hydro-lyase (adding 5-aminolevulinate and cyclizing; porphobilinogen-forming)|delta-aminolevulinic acid dehydrase activity|aminolevulinic dehydratase activity|delta-aminolevulinate dehydratase activity				MetaCyc:PORPHOBILSYNTH-RXN|KEGG_REACTION:R00036|RHEA:24064|Reactome:R-HSA-189439|EC:4.2.1.24									molecular_function											owl:Class	
GO:1903319	biolink:NamedThing	positive regulation of protein maturation	Any process that activates or increases the frequency, rate or extent of protein maturation.	tmpzr1t_l9r_go_relaxed.owl	up regulation of protein maturation|upregulation of protein maturation|activation of protein maturation|up-regulation of protein maturation							vw	2014-08-18T12:59:23Z					biological_process											owl:Class	
GO:0015630	biolink:NamedThing	microtubule cytoskeleton	The part of the cytoskeleton (the internal framework of a cell) composed of microtubules and associated proteins.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:2000181	biolink:NamedThing	negative regulation of blood vessel morphogenesis	Any process that stops, prevents, or reduces the frequency, rate or extent of blood vessel morphogenesis.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-10-13T12:46:31Z					biological_process											owl:Class	
GO:0070407	biolink:NamedThing	oxidation-dependent protein catabolic process	The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the oxidation of one or more amino acid residues in the protein.	tmpzr1t_l9r_go_relaxed.owl	oxidized protein catabolic process|oxidation-dependent proteolysis|oxidation-dependent protein breakdown|oxidation-dependent protein degradation|oxidation-dependent protein catabolism													biological_process											owl:Class	
GO:0019941	biolink:NamedThing	modification-dependent protein catabolic process	The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent modification of the target protein.	tmpzr1t_l9r_go_relaxed.owl	protein degradation tagging activity|modification-initiated protein catabolic process|modification-dependent protein breakdown|protein-ligand-dependent protein catabolism|modification-initiated proteolysis|modification-dependent protein degradation|protein-ligand-dependent protein catabolic process|modification-initiated protein catabolism|modification-dependent proteolysis|modification-dependent protein catabolism													biological_process											owl:Class	
GO:0048003	biolink:NamedThing	antigen processing and presentation of lipid antigen via MHC class Ib	The process in which an antigen-presenting cell expresses lipid antigen in association with an MHC class Ib protein complex on its cell surface, including lipid extraction, degradation, and transport steps for the lipid antigen both prior to and following assembly with the MHC protein complex. The lipid antigen may originate from an endogenous or exogenous source of lipid. Class Ib here refers to non-classical class I molecules, such as those of the CD1 family.	tmpzr1t_l9r_go_relaxed.owl	lipid antigen processing and presentation via MHC class Ib|antigen presentation, lipid antigen													biological_process											owl:Class	
GO:1900711	biolink:NamedThing	negative regulation of tensidol B biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of tensidol B biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	down regulation of tensidol B biosynthetic process|downregulation of tensidol B anabolism|inhibition of tensidol B biosynthetic process|down-regulation of tensidol B biosynthesis|inhibition of tensidol B biosynthesis|down regulation of tensidol B biosynthesis|down-regulation of tensidol B biosynthetic process|down-regulation of tensidol B synthesis|inhibition of tensidol B formation|inhibition of tensidol B anabolism|negative regulation of tensidol B biosynthesis|downregulation of tensidol B synthesis|down regulation of tensidol B formation|downregulation of tensidol B biosynthetic process|down-regulation of tensidol B formation|downregulation of tensidol B formation|negative regulation of tensidol B formation|down-regulation of tensidol B anabolism|negative regulation of tensidol B anabolism|down regulation of tensidol B anabolism|down regulation of tensidol B synthesis|downregulation of tensidol B biosynthesis|negative regulation of tensidol B synthesis|inhibition of tensidol B synthesis							di	2012-05-22T05:03:16Z					biological_process											owl:Class	
GO:0022889	biolink:NamedThing	serine transmembrane transporter activity	Enables the transfer of serine from one side of a membrane to the other. Serine is 2-amino-3-hydroxypropanoic acid.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0061928	biolink:NamedThing	glutathione specific gamma-glutamylcyclotransferase activity	Catalysis of the reaction: glutathione = 5-oxoproline + L-cysteinylglycine.	tmpzr1t_l9r_go_relaxed.owl					RHEA:47724|EC:4.3.2.7			dph	2017-08-29T14:55:30Z					molecular_function											owl:Class	
GO:0016842	biolink:NamedThing	amidine-lyase activity	Catalysis of the release of amides or amidines by the cleavage of a carbon-nitrogen bond or the reverse reaction with an amide or amidine as a substrate.	tmpzr1t_l9r_go_relaxed.owl					EC:4.3.2.-									molecular_function											owl:Class	
GO:1900337	biolink:NamedThing	negative regulation of methane biosynthetic process from carbon monoxide	Any process that stops, prevents or reduces the frequency, rate or extent of methane biosynthetic process from carbon monoxide.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of methane biosynthetic process from carbon monoxide|down regulation of methane biosynthetic process from carbon monoxide|downregulation of methane biosynthetic process from carbon monoxide|inhibition of methane biosynthetic process from carbon monoxide							tt	2012-04-06T02:03:24Z					biological_process											owl:Class	
GO:1902024	biolink:NamedThing	L-histidine transport	The directed movement of a L-histidine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl								kmv	2013-03-27T16:09:15Z					biological_process											owl:Class	
GO:1902022	biolink:NamedThing	L-lysine transport	The directed movement of a L-lysine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl								kmv	2013-03-27T16:09:06Z					biological_process											owl:Class	
GO:0035730	biolink:NamedThing	S-nitrosoglutathione binding	Binding to S-nitrosoglutathione, a nitrosothiol considered to be a natural nitric oxide (NO) donor involved in S-nitrosylation, and in the storage and transport of nitric oxide in biological systems.	tmpzr1t_l9r_go_relaxed.owl	GSNO binding							bf	2011-03-11T09:57:19Z					molecular_function											owl:Class	
GO:1901594	biolink:NamedThing	response to capsazepine	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a capsazepine stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2012-11-07T17:16:53Z					biological_process											owl:Class	
GO:0051037	biolink:NamedThing	regulation of transcription involved in meiotic cell cycle	Any process that modulates the frequency, rate or extent of transcription as part of a meiotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl	meiotic regulation of transcription|regulation of transcription, meiotic													biological_process											owl:Class	
GO:0002576	biolink:NamedThing	platelet degranulation	The regulated exocytosis of secretory granules containing preformed mediators such as histamine and serotonin by a platelet.	tmpzr1t_l9r_go_relaxed.owl	platelet exocytosis													biological_process											owl:Class	
GO:1901775	biolink:NamedThing	mitomycin C metabolic process	The chemical reactions and pathways involving mitomycin C.	tmpzr1t_l9r_go_relaxed.owl	mitomycin C metabolism							yaf	2013-01-15T12:11:48Z					biological_process											owl:Class	
GO:1903932	biolink:NamedThing	regulation of DNA primase activity	Any process that modulates the frequency, rate or extent of DNA primase activity.	tmpzr1t_l9r_go_relaxed.owl								mah	2015-02-12T14:28:26Z					biological_process											owl:Class	
GO:0036501	biolink:NamedThing	UFD1-NPL4 complex	A dimeric protein complex that contains the co-factors for the ATPase VCP/p97 (Cdc48p in budding yeast). In mammals, this complex consists of UFD1L (UFD1) and NPLOC4 (NPL4). In budding yeast, the complex is a dimer of Ufd1p and Npl4p.	tmpzr1t_l9r_go_relaxed.owl	Ufd1-Npl4 binary complex|Ufd1/Npl4 complex|Ufd1-Npl4 cofactor complex|Npl4p-Ufd1p complex|UFD1L-NPLOC4 complex							bf	2015-05-14T10:59:43Z					cellular_component											owl:Class	
GO:0045702	biolink:NamedThing	positive regulation of spermatid nuclear differentiation	Any process that activates or increases the frequency, rate or extent of spermatid nuclear differentiation.	tmpzr1t_l9r_go_relaxed.owl	stimulation of spermatid nuclear differentiation|up-regulation of spermatid nuclear differentiation|activation of spermatid nuclear differentiation|upregulation of spermatid nuclear differentiation|up regulation of spermatid nuclear differentiation													biological_process											owl:Class	
GO:0071642	biolink:NamedThing	positive regulation of macrophage inflammatory protein 1 alpha production	Any process that activates or increases the frequency, rate, or extent of production of macrophage inflammatory protein 1 alpha.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of macrophage inflammatory protein production|positive regulation of CCL3 production|positive regulation of chemokine (C-C motif) ligand 3 production|positive regulation of MIP-1a production							mah	2010-02-12T10:39:51Z					biological_process											owl:Class	
GO:0071640	biolink:NamedThing	regulation of macrophage inflammatory protein 1 alpha production	Any process that modulates the frequency, rate, or extent of production of macrophage inflammatory protein 1 alpha.	tmpzr1t_l9r_go_relaxed.owl	regulation of CCL3 production|regulation of chemokine (C-C motif) ligand 3 production|regulation of MIP-1a production|regulation of macrophage inflammatory protein production							mah	2010-02-12T10:39:51Z					biological_process											owl:Class	
GO:0086086	biolink:NamedThing	voltage-gated potassium channel activity involved in AV node cell action potential repolarization	Catalysis of the transmembrane transfer of a potassium ion by a voltage-gated channel through the plasma membrane of an AV node cardiac muscle cell contributing to the repolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.	tmpzr1t_l9r_go_relaxed.owl	voltage-gated potassium channel activity involved in atrioventricular node cardiac muscle cell action potential|voltage-gated potassium channel activity involved in AV node cardiac muscle cell action potential repolarization							dph	2011-11-22T01:26:32Z					molecular_function											owl:Class	
GO:0070062	biolink:NamedThing	extracellular exosome	A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.	tmpzr1t_l9r_go_relaxed.owl	exosome|extracellular vesicular exosome													cellular_component											owl:Class	
GO:1901762	biolink:NamedThing	oxytetracycline catabolic process	The chemical reactions and pathways resulting in the breakdown of oxytetracycline.	tmpzr1t_l9r_go_relaxed.owl	oxytetracycline breakdown|oxytetracycline degradation|oxytetracycline catabolism							yaf	2013-01-15T09:52:55Z					biological_process											owl:Class	
GO:0006597	biolink:NamedThing	spermine biosynthetic process	The chemical reactions and pathways resulting in the formation of spermine, a polybasic amine found in human sperm, in ribosomes and in some viruses and involved in nucleic acid packaging.	tmpzr1t_l9r_go_relaxed.owl	spermine biosynthesis|spermine synthesis|spermine formation|spermine anabolism													biological_process											owl:Class	
GO:0047273	biolink:NamedThing	galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity	Catalysis of the reaction: UDP-N-acetyl-D-galactosamine + alpha-D-galactosyl-(1->4)-beta-D-galactosyl-(1->4)-beta-D-glucosylceramide = UDP + beta-N-acetyl-D-galactosaminyl-(1->3)-alpha-D-galactosyl-(1->4)-beta-D-galactosyl-(1->4)-beta-D-glucosylceramide.	tmpzr1t_l9r_go_relaxed.owl	globoside synthetase activity|UDP-N-acetyl-D-galactosamine:D-galactosyl-1,4-D-galactosyl-1,4-D-glucosylceramide beta-N-acetyl-D-galactosaminyltransferase activity|UDP-N-acetylgalactosamine:globotriaosylceramide beta1,3-N-acetylgalactosaminyltransferase activity|uridine diphosphoacetylgalactosamine-galactosylgalactosylglucosylceramide acetylgalactosaminyltransferase activity|globotriosylceramide beta-1,6-N-acetylgalactosaminyltransferase activity|beta-3GalNAc-T1 activity|beta3GalNAc-T1|galactosylgalactosylglucosylceramide beta-D- activity|globoside synthase activity|UDP-N-acetylgalactosamine:globotriaosylceramide beta-3-N-acetylgalactosaminyltransferase activity|globotriaosylceramide 3-beta-N-acetylgalactosaminyltransferase activity|UDP-N-acetyl-D-galactosamine:alpha-D-galactosyl-(1->4)-beta-D-galactosyl-(1->4)-beta-D-glucosylceramide 3III-beta-N-acetyl-D-galactosaminyltransferase activity				Reactome:R-HSA-8878914|RHEA:22252|MetaCyc:2.4.1.79-RXN|EC:2.4.1.79							GO:0047226		molecular_function											owl:Class	
GO:0061184	biolink:NamedThing	positive regulation of dermatome development	Any process that increases the rate, frequency, or extent of the progression of the dermatome over time, from its initial formation to the mature structure. The dermatome is the portion of a somite that will form skin.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-07-14T08:42:03Z					biological_process											owl:Class	
GO:0061183	biolink:NamedThing	regulation of dermatome development	Any process that modulates the rate, frequency, or extent of the progression of the dermatome over time, from its initial formation to the mature structure. The dermatome is the portion of a somite that will form skin.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-07-14T08:40:26Z					biological_process											owl:Class	
GO:0032456	biolink:NamedThing	endocytic recycling	The directed movement of membrane-bounded vesicles from endosomes back to the plasma membrane, a trafficking pathway that promotes the recycling of internalized transmembrane proteins.	tmpzr1t_l9r_go_relaxed.owl	retrograde transport of endocytic vesicles|retrograde transport, endosome to plasma membrane	https://github.com/geneontology/go-ontology/issues/20747						sp	2013-06-18T10:52:50Z			GO:1990126		biological_process											owl:Class	
GO:0016197	biolink:NamedThing	endosomal transport	The directed movement of substances mediated by an endosome, a membrane-bounded organelle that carries materials enclosed in the lumen or located in the endosomal membrane.	tmpzr1t_l9r_go_relaxed.owl	endosome localisation|endosome localization|endosome transport											GO:0032439		biological_process											owl:Class	
GO:0006559	biolink:NamedThing	L-phenylalanine catabolic process	The chemical reactions and pathways resulting in the breakdown of phenylalanine, 2-amino-3-phenylpropanoic acid.	tmpzr1t_l9r_go_relaxed.owl	phenylalanine catabolic process|L-phenylalanine catabolism|L-phenylalanine degradation|phenylalanine catabolism|L-phenylalanine breakdown													biological_process											owl:Class	
GO:0033044	biolink:NamedThing	regulation of chromosome organization	Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a chromosome.	tmpzr1t_l9r_go_relaxed.owl	regulation of chromosome organization and biogenesis|regulation of chromosome organisation													biological_process											owl:Class	
GO:0060266	biolink:NamedThing	negative regulation of respiratory burst involved in inflammatory response	Any process that decreases the rate, frequency or extent of a phase of elevated metabolic activity, during which oxygen consumption increases made as a defense response ; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of respiratory burst involved in acute inflammatory response													biological_process											owl:Class	
GO:0007636	biolink:NamedThing	chemosensory jump behavior	The sudden, usually upward, movement off the ground or other surface through sudden muscular effort in the legs, following exposure to a chemical substance.	tmpzr1t_l9r_go_relaxed.owl	jump response to chemical stimulus|chemosensory jump behaviour													biological_process											owl:Class	
GO:0007630	biolink:NamedThing	jump response	The sudden, usually upward, movement off the ground or other surface through sudden muscular effort in the legs, following exposure to an external stimulus.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1900224	biolink:NamedThing	positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry	Any process that activates or increases the frequency, rate or extent of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry.	tmpzr1t_l9r_go_relaxed.owl	upregulation of nodal signaling pathway of determination of left/right asymmetry in lateral mesoderm|positive regulation of nodal signaling of determination of left/right asymmetry in lateral mesoderm|upregulation of nodal signaling of determination of left/right asymmetry in lateral mesoderm|up regulation of nodal signaling pathway of determination of left/right asymmetry in lateral mesoderm|up-regulation of nodal signaling pathway of determination of left/right asymmetry in lateral mesoderm|activation of nodal signaling pathway of determination of left/right asymmetry in lateral mesoderm|up-regulation of nodal signaling of determination of left/right asymmetry in lateral mesoderm|positive regulation of nodal signaling pathway of determination of left/right asymmetry in lateral mesoderm|up regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry|activation of nodal signaling of determination of left/right asymmetry in lateral mesoderm|positive regulation of nodal signalling pathway involved in determination of lateral mesoderm left/right asymmetry|up regulation of nodal signaling of determination of left/right asymmetry in lateral mesoderm|up-regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry|activation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry|upregulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry							vk	2012-03-22T02:30:13Z					biological_process											owl:Class	
GO:0032757	biolink:NamedThing	positive regulation of interleukin-8 production	Any process that activates or increases the frequency, rate, or extent of interleukin-8 production.	tmpzr1t_l9r_go_relaxed.owl	activation of interleukin-8 production|stimulation of interleukin-8 production|up-regulation of interleukin-8 production|positive regulation of interleukin-8 biosynthetic process|up regulation of interleukin-8 production|positive regulation of interleukin-8 secretion|upregulation of interleukin-8 production|positive regulation of IL-8 production											GO:0045416|GO:2000484		biological_process											owl:Class	
GO:0034842	biolink:NamedThing	thiophene-2-carboxylate-CoA ligase activity	Catalysis of the reaction: thiophene-2-carboxylate + ATP + CoASH = thiophene-2-carboxyl-CoA + AMP + PPi.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r1234									molecular_function											owl:Class	
GO:0103058	biolink:NamedThing	kaempferol 3-glucoside 7-O-rhamnosyltransferase activity	Catalysis of the reaction: kaempferol 3-O-glucoside + UDP-L-rhamnose <=> kaempferol-3-glucoside-7-rhamnoside + UDP.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN1F-443									molecular_function											owl:Class	
GO:0032334	biolink:NamedThing	inhibin secretion	The regulated release of an inhibin, either of two glycoproteins (designated A and B), secreted by the gonads and present in seminal plasma and follicular fluid, that inhibit pituitary production of follicle-stimulating hormone.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0060986	biolink:NamedThing	endocrine hormone secretion	The regulated release of a hormone into the circulatory system.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-01-11T09:03:48Z					biological_process											owl:Class	
GO:0018261	biolink:NamedThing	peptidyl-lysine guanylylation	The guanylylation of peptidyl-lysine to form peptidyl-N6-(phospho-5'-guanosine)-L-lysine.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0228									biological_process											owl:Class	
GO:0038166	biolink:NamedThing	angiotensin-activated signaling pathway	The series of molecular signals generated as a consequence of angiotensin II binding to an angiotensin receptor on the surface of the cell, and proceeding with the activated receptor transmitting the signal to a heterotrimeric G-protein complex to initiate a change in cell activity. Ends with regulation of a downstream cellular process, e.g. transcription.	tmpzr1t_l9r_go_relaxed.owl	angiotensin-mediated signaling pathway|angiotensin receptor signaling pathway|angiotensin II-mediated signaling pathway							bf	2012-05-14T03:09:03Z					biological_process											owl:Class	
GO:0070446	biolink:NamedThing	negative regulation of oligodendrocyte progenitor proliferation	Any process that stops or decreases the rate or extent of oligodendrocyte progenitor proliferation.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of oligodendrocyte precursor proliferation													biological_process											owl:Class	
GO:0110021	biolink:NamedThing	cardiac muscle myoblast proliferation	The multiplication or reproduction of cardiac muscle myoblasts, resulting in the expansion of a cardiac muscle myoblast cell population.  A cardiac myoblast is a precursor cell that has been committed to a cardiac muscle cell fate but retains the ability to divide and proliferate throughout life.	tmpzr1t_l9r_go_relaxed.owl								kmv	2017-06-29T14:35:24Z					biological_process											owl:Class	
GO:0051450	biolink:NamedThing	myoblast proliferation	The multiplication or reproduction of myoblasts, resulting in the expansion of a myoblast cell population. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0035204	biolink:NamedThing	negative regulation of lamellocyte differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of lamellocyte differentiation. Lamellocytes differentiate massively in the lymph glands after parasitization and are large flat cells devoted to encapsulation of invaders too large to be phagocytosed by plasmatocytes.	tmpzr1t_l9r_go_relaxed.owl	inhibition of lamellocyte differentiation|down-regulation of lamellocyte differentiation|down regulation of lamellocyte differentiation|downregulation of lamellocyte differentiation													biological_process											owl:Class	
GO:0045614	biolink:NamedThing	negative regulation of plasmatocyte differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of plasmatocyte differentiation.	tmpzr1t_l9r_go_relaxed.owl	inhibition of plasmatocyte differentiation|down-regulation of plasmatocyte differentiation|down regulation of plasmatocyte differentiation|downregulation of plasmatocyte differentiation													biological_process											owl:Class	
GO:0071487	biolink:NamedThing	cellular response to low light intensity stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a low light intensity stimulus. Low light intensity is defined as a level of electromagnetic radiation at or below 0.1 micromols/m2.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-12-18T02:13:29Z					biological_process											owl:Class	
GO:0009645	biolink:NamedThing	response to low light intensity stimulus	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a low light intensity stimulus. Low light intensity is defined as a level of electromagnetic radiation at or below 0.1 micromols/m2.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1903886	biolink:NamedThing	positive regulation of chemokine (C-C motif) ligand 20 production	Any process that activates or increases the frequency, rate or extent of chemokine (C-C motif) ligand 20 production.	tmpzr1t_l9r_go_relaxed.owl	activation of CCL20 production|upregulation of chemokine (C-C motif) ligand 20 production|positive regulation of C-C motif chemokine 20 production|up regulation of CCL20 production|upregulation of CCL20 production|up regulation of CCL-20 production|upregulation of CCL-20 production|up-regulation of CCL-20 production|upregulation of C-C motif chemokine 20 production|activation of CCL-20 production|up-regulation of chemokine (C-C motif) ligand 20 production|up-regulation of CCL20 production|activation of chemokine (C-C motif) ligand 20 production|up regulation of C-C motif chemokine 20 production|up-regulation of C-C motif chemokine 20 production|activation of C-C motif chemokine 20 production|positive regulation of CCL20 production|positive regulation of CCL-20 production|up regulation of chemokine (C-C motif) ligand 20 production							krc	2015-02-06T16:31:20Z					biological_process											owl:Class	
GO:1902060	biolink:NamedThing	positive regulation of sporocarp development involved in sexual reproduction	Any process that activates or increases the frequency, rate or extent of sporocarp development involved in sexual reproduction.	tmpzr1t_l9r_go_relaxed.owl	up regulation of perfect stage fruiting body development|up regulation of sporocarp development involved in sexual reproduction|upregulation of fruiting body development involved in sexual reproduction|up-regulation of perfect stage fruiting body development|positive regulation of fruiting body formation involved in sexual reproduction|activation of sporocarp development involved in sexual reproduction|up-regulation of ascus development|activation of fruiting body development involved in sexual reproduction|positive regulation of perfect stage fruiting body development|up-regulation of fruiting body formation involved in sexual reproduction|upregulation of ascus development|activation of ascus development|activation of perfect stage fruiting body development|up-regulation of fruiting body development involved in sexual reproduction|positive regulation of fruiting body development involved in sexual reproduction|activation of fruiting body formation involved in sexual reproduction|up-regulation of sporocarp development involved in sexual reproduction|up regulation of ascus development|upregulation of perfect stage fruiting body development|upregulation of sporocarp development involved in sexual reproduction|up regulation of fruiting body development involved in sexual reproduction|up regulation of fruiting body formation involved in sexual reproduction|positive regulation of ascus development|upregulation of fruiting body formation involved in sexual reproduction							di	2013-04-16T04:08:47Z					biological_process											owl:Class	
GO:0080094	biolink:NamedThing	response to trehalose-6-phosphate	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a trehalose-6-phosphate stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to trehalose-6-phosphate stimulus							dhl	2009-04-22T04:49:13Z					biological_process											owl:Class	
GO:1901711	biolink:NamedThing	negative regulation of homoserine biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of homoserine biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	inhibition of homoserine formation|negative regulation of homoserine formation|downregulation of homoserine biosynthesis|negative regulation of homoserine synthesis|inhibition of homoserine anabolism|down regulation of homoserine formation|down-regulation of homoserine biosynthesis|down regulation of homoserine biosynthesis|down-regulation of homoserine formation|down-regulation of homoserine anabolism|inhibition of homoserine biosynthetic process|down-regulation of homoserine biosynthetic process|down-regulation of homoserine synthesis|inhibition of homoserine biosynthesis|down regulation of homoserine synthesis|negative regulation of homoserine anabolism|negative regulation of homoserine biosynthesis|inhibition of homoserine synthesis|down regulation of homoserine anabolism|downregulation of homoserine formation|downregulation of homoserine synthesis|down regulation of homoserine biosynthetic process|downregulation of homoserine biosynthetic process|downregulation of homoserine anabolism							mcc	2012-12-19T16:02:00Z					biological_process											owl:Class	
GO:0022010	biolink:NamedThing	central nervous system myelination	The process in which neuronal axons and dendrites become coated with a segmented lipid-rich sheath (myelin) to enable faster and more energetically efficient conduction of electrical impulses. The sheath is formed by the cell membranes of oligodendrocytes in the central nervous system. Adjacent myelin segments are separated by a non-myelinated stretch of axon called a node of Ranvier.	tmpzr1t_l9r_go_relaxed.owl	myelination in central nervous system													biological_process											owl:Class	
GO:0042552	biolink:NamedThing	myelination	The process in which myelin sheaths are formed and maintained around neurons. Oligodendrocytes in the brain and spinal cord and Schwann cells in the peripheral nervous system wrap axons with compact layers of their plasma membrane. Adjacent myelin segments are separated by a non-myelinated stretch of axon called a node of Ranvier.	tmpzr1t_l9r_go_relaxed.owl	myelinogenesis				Wikipedia:Myelin									biological_process											owl:Class	
GO:0052857	biolink:NamedThing	NADPHX epimerase activity	Catalysis of the reaction: (R)-NADPHX = (S)-NADPHX.	tmpzr1t_l9r_go_relaxed.owl					EC:5.1.99.6|Reactome:R-HSA-6806966|RHEA:32227									molecular_function											owl:Class	
GO:0016854	biolink:NamedThing	racemase and epimerase activity	Catalysis of a reaction that alters the configuration of one or more chiral centers in a molecule.	tmpzr1t_l9r_go_relaxed.owl	racemase and epimerase activity, acting on other compounds				EC:5.1.-.-	Note that 'epimerase' refers to the conversion of an epimer into its diastereoisomer, and 'racemase' refers to the interconversion of the two enantiomers of a chiral compound.								molecular_function											owl:Class	
GO:0010692	biolink:NamedThing	regulation of alkaline phosphatase activity	Any process that modulates the frequency, rate or extent of alkaline phosphatase activity, the catalysis of the reaction: an orthophosphoric monoester + H2O = an alcohol + phosphate, with an alkaline pH optimum.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0071411	biolink:NamedThing	cellular response to fluoxetine	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fluoxetine stimulus. Fluoxetine increases the extracellular level of the neurotransmitter serotonin by inhibiting its reuptake into the presynaptic cell, increasing the level of serotonin available to bind to the postsynaptic receptor.	tmpzr1t_l9r_go_relaxed.owl						Note that this term is in the subset of terms that should not be used for direct manual annotation of gene products. Direct annotations to this term may be amended during annotation QC.		mah	2009-12-14T03:09:58Z					biological_process											owl:Class	
GO:0014076	biolink:NamedThing	response to fluoxetine	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fluoxetine stimulus. Fluoxetine increases the extracellular level of the neurotransmitter serotonin by inhibiting its reuptake into the presynaptic cell, increasing the level of serotonin available to bind to the postsynaptic receptor.	tmpzr1t_l9r_go_relaxed.owl	response to SSRI|response to selective serotonin reuptake inhibitor					Note that this term is in the subset of terms that should not be used for direct manual annotation of gene products. Direct annotations to this term may be amended during annotation QC.								biological_process											owl:Class	
GO:0017159	biolink:NamedThing	pantetheine hydrolase activity	Catalysis of the reaction: (R)-pantetheine + H(2)O = (R)-pantothenate + cysteamine.	tmpzr1t_l9r_go_relaxed.owl	vanin-1|vanin|pantetheinase activity|(R)-pantetheine amidohydrolase activity				KEGG_REACTION:R02973|Reactome:R-HSA-8938300|RHEA:13445|EC:3.5.1.92|MetaCyc:3.5.1.92-RXN									molecular_function											owl:Class	
GO:0001849	biolink:NamedThing	complement component C1q complex binding	Binding to a C1q complex, a component of the classical complement cascade.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1902492	biolink:NamedThing	positive regulation of sperm capacitation	Any process that activates or increases the frequency, rate or extent of sperm capacitation.	tmpzr1t_l9r_go_relaxed.owl	activation of sperm capacitation|up-regulation of sperm activation|up regulation of sperm activation|upregulation of sperm activation|up regulation of sperm capacitation|activation of sperm activation|positive regulation of sperm activation|upregulation of sperm capacitation|up-regulation of sperm capacitation							hjd	2013-11-12T21:17:21Z					biological_process											owl:Class	
GO:1902490	biolink:NamedThing	regulation of sperm capacitation	Any process that modulates the frequency, rate or extent of sperm capacitation.	tmpzr1t_l9r_go_relaxed.owl	regulation of sperm activation							hjd	2013-11-12T21:17:03Z					biological_process											owl:Class	
GO:0046622	biolink:NamedThing	positive regulation of organ growth	Any process that activates or increases the frequency, rate or extent of growth of an organ of an organism.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0046620	biolink:NamedThing	regulation of organ growth	Any process that modulates the frequency, rate or extent of growth of an organ of an organism.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0010229	biolink:NamedThing	inflorescence development	The process whose specific outcome is the progression of an inflorescence over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0051348	biolink:NamedThing	negative regulation of transferase activity	Any process that stops or reduces the rate of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from a donor compound to an acceptor.	tmpzr1t_l9r_go_relaxed.owl	inhibition of transferase activity|transferase inhibitor|downregulation of transferase activity|down-regulation of transferase activity|down regulation of transferase activity					This term is useful for grouping, but is too general for manual annotation. Please use a child term instead.								biological_process											owl:Class	
GO:0070419	biolink:NamedThing	nonhomologous end joining complex	A protein complex that plays a role in DNA double-strand break repair via nonhomologous end joining. Such complexes typically contain a specialized DNA ligase (e.g. Lig4 in eukaryotes) and one or more proteins that bind to DNA ends.	tmpzr1t_l9r_go_relaxed.owl	NHEJ complex|non-homologous end joining complex													cellular_component											owl:Class	
GO:0030547	biolink:NamedThing	signaling receptor inhibitor activity	Binds to and modulates the activity of a signaling receptor.	tmpzr1t_l9r_go_relaxed.owl	receptor inhibitor activity													molecular_function											owl:Class	
GO:1900595	biolink:NamedThing	(+)-kotanin catabolic process	The chemical reactions and pathways resulting in the breakdown of (+)-kotanin.	tmpzr1t_l9r_go_relaxed.owl	(+)-kotanin breakdown|(+)-kotanin catabolism|(+)-kotanin degradation							di	2012-05-15T06:54:40Z					biological_process											owl:Class	
GO:0008381	biolink:NamedThing	mechanosensitive ion channel activity	Enables the transmembrane transfer of an ion by a channel that opens in response to a mechanical stress.	tmpzr1t_l9r_go_relaxed.owl	mechanically gated channel activity|mechanically-gated channel activity|mechanically-gated ion channel activity				TC:1.A.23.2.1							GO:0022833		molecular_function											owl:Class	
GO:0099147	biolink:NamedThing	extrinsic component of postsynaptic density membrane	The component of the postsynaptic density membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.	tmpzr1t_l9r_go_relaxed.owl								dos	2017-07-05T10:44:43Z					cellular_component											owl:Class	
GO:0005507	biolink:NamedThing	copper ion binding	Binding to a copper (Cu) ion.	tmpzr1t_l9r_go_relaxed.owl	copper/cadmium binding|copper binding													molecular_function											owl:Class	
GO:0046992	biolink:NamedThing	oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond	Catalysis of an oxidation-reduction (redox) reaction in which X-H and Y-H form X-Y.	tmpzr1t_l9r_go_relaxed.owl	oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond, with other acceptors				EC:1.21.-.-									molecular_function											owl:Class	
GO:1904750	biolink:NamedThing	negative regulation of protein localization to nucleolus	Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to nucleolus.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of protein localization to nucleolus|inhibition of protein localisation to nucleolus|inhibition of protein localization in nucleolus|down-regulation of protein localization in nucleolus|negative regulation of protein localisation to nucleolus|down regulation of protein localisation in nucleolus|downregulation of protein localisation in nucleolus|negative regulation of protein localisation in nucleolus|inhibition of protein localisation in nucleolus|down-regulation of protein localisation to nucleolus|downregulation of protein localisation to nucleolus|inhibition of protein localization to nucleolus|downregulation of protein localization in nucleolus|down regulation of protein localization in nucleolus|negative regulation of protein localization in nucleolus|down-regulation of protein localisation in nucleolus|downregulation of protein localization to nucleolus|down regulation of protein localisation to nucleolus|down regulation of protein localization to nucleolus							nc	2015-10-19T15:16:24Z					biological_process											owl:Class	
GO:1904749	biolink:NamedThing	regulation of protein localization to nucleolus	Any process that modulates the frequency, rate or extent of protein localization to nucleolus.	tmpzr1t_l9r_go_relaxed.owl	regulation of protein localization in nucleolus|regulation of protein localisation in nucleolus|regulation of protein localisation to nucleolus							nc	2015-10-19T15:16:17Z					biological_process											owl:Class	
GO:0001858	biolink:NamedThing	complement component iC3b receptor activity	Combining with the iC3b product of the complement cascade and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0004875	biolink:NamedThing	complement receptor activity	Combining with any component or product of the complement cascade and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	anaphylatoxin receptor activity					Note that the complement cascade includes all of the components involved in the classical complement pathway, the alternative complement pathway, and the lectin complement pathway, as well as the common components of all three pathways.						GO:0004942		molecular_function											owl:Class	
GO:0085015	biolink:NamedThing	dormancy maintenance of symbiont in host	Any process in which a dormant state is maintained by the symbiont within the host organism.	tmpzr1t_l9r_go_relaxed.owl	NRP|non-replicating persistence							jl	2010-05-19T03:17:32Z					biological_process											owl:Class	
GO:0044573	biolink:NamedThing	nitrogenase P cluster assembly	The biochemical reactions and pathways resulting in the formation of a P-cluster of a nitrogenase, a high-nuclearity, Fe/S-only cluster that can be viewed as two [4Fe-4S] sub-clusters sharing a gamma-6-sulfide.	tmpzr1t_l9r_go_relaxed.owl	nitrogenase P cluster maturation|nitrogenase P cluster biosynthesis							jl	2012-04-18T03:29:04Z					biological_process											owl:Class	
GO:0098854	biolink:NamedThing	podocyte primary projection	A cell projection originating from a renal glomerular podocyte and extending to the renal glomerular podocyte foot.	tmpzr1t_l9r_go_relaxed.owl	podocyte major process|glomerular visceral epithelial cell primary projection|primary podocyte process													cellular_component											owl:Class	
GO:0004336	biolink:NamedThing	galactosylceramidase activity	Catalysis of the reaction: D-galactosyl-N-acylsphingosine + H2O = D-galactose + N-acylsphingosine.	tmpzr1t_l9r_go_relaxed.owl	galcerase activity|galactosylceramide beta-galactosidase activity|galactocerebrosidase activity|lactosylceramidase I|galactosylceramidase I|galactosylcerebrosidase activity|D-galactosyl-N-acylsphingosine galactohydrolase activity|beta-galactocerebrosidase activity|galactocerebroside beta-galactosidase activity|galactocerebroside-beta-D-galactosidase activity|lactosylceramidase activity|galactocerebroside galactosidase activity|ceramide galactosidase activity|beta-galactosylceramidase activity|cerebroside galactosidase activity|cerebroside beta-galactosidase activity				MetaCyc:GALACTOSYLCERAMIDASE-RXN|EC:3.2.1.46|Reactome:R-HSA-1606564|RHEA:14297									molecular_function											owl:Class	
GO:0034701	biolink:NamedThing	tripeptidase activity	Catalysis of the hydrolysis of a tripeptide.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:3.4.11.4-RXN|EC:3.4.13.-									molecular_function											owl:Class	
GO:0097421	biolink:NamedThing	liver regeneration	The regrowth of lost or destroyed liver.	tmpzr1t_l9r_go_relaxed.owl								pr	2012-11-07T10:22:43Z					biological_process											owl:Class	
GO:0001889	biolink:NamedThing	liver development	The process whose specific outcome is the progression of the liver over time, from its formation to the mature structure. The liver is an exocrine gland which secretes bile and functions in metabolism of protein and carbohydrate and fat, synthesizes substances involved in the clotting of the blood, synthesizes vitamin A, detoxifies poisonous substances, stores glycogen, and breaks down worn-out erythrocytes.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1902894	biolink:NamedThing	negative regulation of pri-miRNA transcription by RNA polymerase II	Any process that stops, prevents or reduces the frequency, rate or extent of pri-miRNA transcription mediated by RNA polymerase II.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of pri-miRNA transcription from RNA polymerase II promoter|inhibition of pri-miRNA transcription from RNA polymerase II promoter|downregulation of pri-miRNA transcription from RNA polymerase II promoter|down-regulation of pri-miRNA transcription from RNA polymerase II promoter|down regulation of pri-miRNA transcription from RNA polymerase II promoter							dph	2014-04-08T13:22:14Z					biological_process											owl:Class	
GO:0033111	biolink:NamedThing	attachment organelle membrane	The lipid bilayer surrounding an attachment organelle.  This is a region of the cell membrane facing the environment - in mycoplasma, part of the mycolate outer membrane.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0140415	biolink:NamedThing	effector-mediated modulation of host defenses by symbiont	A process mediated by a molecule secreted by a symbiont that results in the modulation (either activation or suppresion) of a defense response. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl								pg	2020-01-20T16:46:41Z					biological_process											owl:Class	
GO:0033100	biolink:NamedThing	NuA3 histone acetyltransferase complex	A Gcn5-independent multisubunit complex that catalyzes the acetylation of histone H3. The budding yeast complex includes Sas3p, Taf30p, and Yng1p.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0070775	biolink:NamedThing	H3 histone acetyltransferase complex	A multisubunit complex that catalyzes the acetylation of histone H3.	tmpzr1t_l9r_go_relaxed.owl	H3 HAT complex							mah	2009-07-02T11:56:48Z					cellular_component											owl:Class	
GO:0090089	biolink:NamedThing	regulation of dipeptide transport	Any process that modulates the rate, frequency or extent of dipeptide transport. Dipeptide transport is the directed movement of a dipeptide, a combination of two amino acids by means of a peptide (-CO-NH-) link, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-10-23T11:24:36Z					biological_process											owl:Class	
GO:0090088	biolink:NamedThing	regulation of oligopeptide transport	Any process that modulates the frequency, rate or extent of the directed movement of oligopeptides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Oligopeptides are molecules that contain a small number (2 to 20) of amino-acid residues connected by peptide linkages.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-10-23T11:23:18Z					biological_process											owl:Class	
GO:0031867	biolink:NamedThing	EP4 subtype prostaglandin E2 receptor binding	Binding to an EP4 subtype prostaglandin E2 receptor.	tmpzr1t_l9r_go_relaxed.owl	EP4 subtype prostaglandin E2 receptor ligand|prostanoid EP4 receptor binding													molecular_function											owl:Class	
GO:0031862	biolink:NamedThing	prostanoid receptor binding	Binding to a prostanoid receptor.	tmpzr1t_l9r_go_relaxed.owl	prostanoid receptor ligand													molecular_function											owl:Class	
GO:1990228	biolink:NamedThing	sulfurtransferase complex	A protein complex capable of catalyzing the transfer of sulfur atoms from one compound (donor) to another (acceptor).	tmpzr1t_l9r_go_relaxed.owl	sulfur transfer complex|SufE complex|ThiF-ThiS complex|SufE dimer							bhm	2013-11-12T09:08:23Z					cellular_component											owl:Class	
GO:0002621	biolink:NamedThing	positive regulation of non-professional antigen presenting cell antigen processing and presentation	Any process that activates or increases the frequency, rate, or extent of non-professional antigen presenting cell antigen processing and presentation.	tmpzr1t_l9r_go_relaxed.owl	up regulation of non-professional antigen presenting cell antigen processing and presentation|up-regulation of non-professional antigen presenting cell antigen processing and presentation|stimulation of non-professional antigen presenting cell antigen processing and presentation|upregulation of non-professional antigen presenting cell antigen processing and presentation|activation of non-professional antigen presenting cell antigen processing and presentation													biological_process											owl:Class	
GO:1903368	biolink:NamedThing	regulation of foraging behavior	Any process that modulates the frequency, rate or extent of foraging behavior.	tmpzr1t_l9r_go_relaxed.owl								mr	2014-08-22T03:03:04Z					biological_process											owl:Class	
GO:1900181	biolink:NamedThing	negative regulation of protein localization to nucleus	Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to nucleus.	tmpzr1t_l9r_go_relaxed.owl	down regulation of protein localization to nucleus|inhibition of protein localization in nucleus|down regulation of protein localization in cell nucleus|down-regulation of protein localisation to nucleus|downregulation of protein localization in nucleus|negative regulation of protein localization in nucleus|negative regulation of protein localisation to nucleus|down regulation of protein localization in nucleus|down-regulation of protein localization in cell nucleus|inhibition of protein localisation to nucleus|down-regulation of protein localization in nucleus|inhibition of protein localization to nucleus|negative regulation of protein localization in cell nucleus|inhibition of protein localization in cell nucleus|down-regulation of protein localization to nucleus|downregulation of protein localization in cell nucleus|downregulation of protein localisation to nucleus|down regulation of protein localisation to nucleus|downregulation of protein localization to nucleus							bf	2012-03-12T01:23:48Z					biological_process											owl:Class	
GO:2000631	biolink:NamedThing	regulation of pre-miRNA processing	Any process that modulates the frequency, rate or extent of pre-microRNA processing.	tmpzr1t_l9r_go_relaxed.owl	regulation of pre-microRNA processing							dph	2011-04-18T03:50:16Z					biological_process											owl:Class	
GO:0004950	biolink:NamedThing	chemokine receptor activity	Combining with a chemokine, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. Chemokines are a family of small chemotactic cytokines; their name is derived from their ability to induce directed chemotaxis in nearby responsive cells. All chemokines possess a number of conserved cysteine residues involved in intramolecular disulfide bond formation. Some chemokines are considered pro-inflammatory and can be induced during an immune response to recruit cells of the immune system to a site of infection, while others are considered homeostatic and are involved in controlling the migration of cells during normal processes of tissue maintenance or development. Chemokines are found in all vertebrates, some viruses and some bacteria.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0046009	biolink:NamedThing	positive regulation of female receptivity, post-mating	Any process that increases the receptiveness of a female to male advances subsequent to mating.	tmpzr1t_l9r_go_relaxed.owl	upregulation of female receptivity, post-mating|activation of female receptivity, post-mating|up-regulation of female receptivity, post-mating|up regulation of female receptivity, post-mating|stimulation of female receptivity, post-mating													biological_process											owl:Class	
GO:0046008	biolink:NamedThing	regulation of female receptivity, post-mating	Any process that modulates the receptiveness of a female to male advances subsequent to mating.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0047089	biolink:NamedThing	dihydrochelirubine 12-monooxygenase activity	Catalysis of the reaction: dihydrochelirubine + H(+) + NADPH + O(2) = 12-hydroxydihydrochelirubine + H(2)O + NADP(+).	tmpzr1t_l9r_go_relaxed.owl	dihydrochelirubine 12-hydroxylase activity|dihydrochelirubine,NADPH:oxygen oxidoreductase (12-hydroxylating)				KEGG_REACTION:R04708|RHEA:10156|MetaCyc:1.14.13.57-RXN|EC:1.14.14.101									molecular_function											owl:Class	
GO:0060240	biolink:NamedThing	negative regulation of signal transduction involved in conjugation with cellular fusion	Any process that decreases the rate, frequency or extent of the series of molecular signals that bring about the relay, amplification or dampening of a signal generated in response to a cue, such as starvation or pheromone exposure, in organisms that undergo conjugation with cellular fusion.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0016261	biolink:NamedThing	selenocysteine catabolic process	The chemical reactions and pathways resulting in the breakdown of selenocysteine, an essential component of glutathione peroxidase and some other proteins.	tmpzr1t_l9r_go_relaxed.owl	selenocysteine degradation|selenocysteine breakdown|selenocysteine catabolism													biological_process											owl:Class	
GO:0044262	biolink:NamedThing	cellular carbohydrate metabolic process	The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y, as carried out by individual cells.	tmpzr1t_l9r_go_relaxed.owl	main pathways of carbohydrate metabolic process|cellular carbohydrate metabolism|main pathways of carbohydrate metabolism											GO:0006092		biological_process											owl:Class	
GO:0070480	biolink:NamedThing	exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-independent decay	The chemical reactions and pathways resulting in the breakdown of the transcript body of a nuclear-transcribed mRNA that occurs independent of deadenylation, but requires decapping followed by transcript decay.	tmpzr1t_l9r_go_relaxed.owl	exonucleolytic nuclear-transcribed mRNA catabolism involved in deadenylation-independent decay|exonucleolytic nuclear-transcribed mRNA breakdown involved in deadenylation-independent decay|exonucleolytic nuclear-transcribed mRNA degradation involved in deadenylation-independent decay													biological_process											owl:Class	
GO:0006622	biolink:NamedThing	protein targeting to lysosome	The process of directing proteins towards the lysosome using signals contained within the protein.	tmpzr1t_l9r_go_relaxed.owl	protein-lysosome targeting													biological_process											owl:Class	
GO:0046484	biolink:NamedThing	oxazole or thiazole metabolic process	The chemical reactions and pathways involving oxazole or thiazole, five-membered heterocyclic ring structures containing an oxygen and a sulfur, respectively, in the 1-position and a nitrogen in the 3-position.	tmpzr1t_l9r_go_relaxed.owl	oxazole or thiazole metabolism													biological_process											owl:Class	
GO:0046488	biolink:NamedThing	phosphatidylinositol metabolic process	The chemical reactions and pathways involving phosphatidylinositol, any glycophospholipid in which a sn-glycerol 3-phosphate residue is esterified to the 1-hydroxyl group of 1D-myo-inositol.	tmpzr1t_l9r_go_relaxed.owl	PtdIns metabolic process|phosphoinositide metabolism|phosphoinositide metabolic process|PtdIns metabolism|phosphatidylinositol metabolism											GO:0030384		biological_process											owl:Class	
GO:0008787	biolink:NamedThing	allose kinase activity	Catalysis of the reaction: ATP + D-allose = ADP + D-allose 6-phosphate.	tmpzr1t_l9r_go_relaxed.owl	allokinase (phosphorylating)|D-allose-6-kinase activity|D-allokinase activity|allokinase activity|ATP:D-allose 6-phosphotransferase activity				RHEA:14805|EC:2.7.1.55|MetaCyc:ALLOSE-KINASE-RXN									molecular_function											owl:Class	
GO:0038135	biolink:NamedThing	ERBB2-ERBB4 signaling pathway	A series of molecular signals initiated by binding of a ligand to a ERBB4 receptor on the surface of a cell, followed by transmission of the signal by a heterodimeric complex of ERBB2 and ERBB4. ERBB2, which does not bind any known ligand, is activated through formation of a heterodimer with another ligand-activated ERBB family member such as ERBB4.	tmpzr1t_l9r_go_relaxed.owl	ERBB2-ERBB4 signalling pathway|HER2-HER4 signaling pathway							bf	2012-03-30T11:19:52Z					biological_process											owl:Class	
GO:0038128	biolink:NamedThing	ERBB2 signaling pathway	A series of molecular signals initiated by binding of a ligand to a member of the ERBB family of receptors on the surface of a cell, where the signal is transmitted by ERBB2. The pathway ends with regulation of a downstream cellular process, e.g. transcription. ERBB2 receptors are themselves unable to bind to ligands, but act as a signal-amplifying tyrosine kinase within a heterodimeric pair.	tmpzr1t_l9r_go_relaxed.owl	ERBB2 signalling pathway|receptor tyrosine-protein kinase erbB-2 signaling pathway|NEU signaling|HER2 signaling pathway							bf	2012-03-30T10:05:12Z					biological_process											owl:Class	
GO:1902480	biolink:NamedThing	protein localization to mitotic spindle	A process in which a protein is transported to, or maintained in, a location within a mitotic spindle.	tmpzr1t_l9r_go_relaxed.owl	protein localization in mitotic spindle|protein localisation in mitotic spindle|protein localisation to mitotic spindle							mah	2013-11-04T13:16:47Z					biological_process											owl:Class	
GO:0072698	biolink:NamedThing	protein localization to microtubule cytoskeleton	A cellular protein localization process in which a protein is transported to, or maintained at, a location within the microtubule cytoskeleton.	tmpzr1t_l9r_go_relaxed.owl	protein localisation to microtubule cytoskeleton							mah	2012-04-11T01:19:35Z					biological_process											owl:Class	
GO:0090433	biolink:NamedThing	palmitoyl-CoA ligase activity	Catalysis of the reaction: ATP + palmitic acid + CoA = AMP + diphosphate + palmitoyl-CoA.	tmpzr1t_l9r_go_relaxed.owl	palmitoyl-CoA synthetase activity				Reactome:R-HSA-434382			tb	2012-07-25T03:31:31Z					molecular_function											owl:Class	
GO:0004467	biolink:NamedThing	long-chain fatty acid-CoA ligase activity	Catalysis of the reaction: ATP + a long-chain fatty acid + CoA = AMP + diphosphate + an acyl-CoA; a long-chain fatty acid is a fatty acid with a chain length between C13 and C22.	tmpzr1t_l9r_go_relaxed.owl	acyl-CoA synthetase activity|pristanoyl-CoA synthetase|LCFA synthetase activity|long-chain fatty acyl coenzyme A synthetase activity|acyl-CoA ligase activity|thiokinase|long-chain-fatty-acyl-CoA synthetase activity|fatty acid thiokinase (long-chain) activity|long chain fatty acyl-CoA synthetase activity|long-chain fatty acid activation|stearoyl-CoA synthetase|long-chain acyl CoA synthetase activity|long-chain acyl-CoA synthetase activity|acyl-activating enzyme activity|long-chain-fatty-acid-CoA ligase activity|lignoceroyl-CoA synthase activity|long-chain acyl-coenzyme A synthetase activity	https://github.com/geneontology/go-ontology/issues/20462|https://github.com/geneontology/go-ontology/issues/18967			Reactome:R-HSA-193407|Reactome:R-HSA-193711|EC:6.2.1.3|Reactome:R-HSA-193766|Reactome:R-HSA-548843|Reactome:R-HSA-193424|Reactome:R-HSA-192137|RHEA:15421|Reactome:R-HSA-2046098|Reactome:R-HSA-201035|Reactome:R-HSA-193743|Reactome:R-HSA-159425|MetaCyc:ACYLCOASYN-RXN|Reactome:R-HSA-2046085|MetaCyc:PWY-5143|UM-BBD_enzymeID:e0025|Reactome:R-HSA-5696004|Reactome:R-HSA-193727|Reactome:R-HSA-193401							GO:0003996		molecular_function											owl:Class	
GO:0016690	biolink:NamedThing	diarylpropane peroxidase activity	Catalysis of the reaction: (3,4-dimethoxyphenyl)methanol + H2O2 = 3,4-dimethoxybenzaldehyde + 2 H2O.	tmpzr1t_l9r_go_relaxed.owl	diarylpropane:oxygen,hydrogen-peroxide oxidoreductase (C-C-bond-cleaving)|ligninase I activity|LiP activity|ligninase activity|lignin peroxidase activity|diarylpropane oxygenase activity|1,2-bis(3,4-dimethoxyphenyl)propane-1,3-diol:hydrogen-peroxide oxidoreductase activity				RHEA:30271|MetaCyc:DIARYLPROPANE-PEROXIDASE-RXN|EC:1.11.1.14									molecular_function											owl:Class	
GO:0036172	biolink:NamedThing	thiamine salvage	A process that generates thiamine (vitamin B1) from derivatives of it without de novo synthesis.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:PWY-6897|MetaCyc:PWY-6896|MetaCyc:PWY-6898			bf	2012-03-29T10:31:05Z					biological_process											owl:Class	
GO:0009228	biolink:NamedThing	thiamine biosynthetic process	The chemical reactions and pathways resulting in the formation of thiamine (vitamin B1), a water soluble vitamin present in fresh vegetables and meats, especially liver.	tmpzr1t_l9r_go_relaxed.owl	thiamine formation|thiamine synthesis|thiamine biosynthesis|vitamin B1 biosynthesis|vitamin B1 biosynthetic process|thiamin biosynthetic process|thiamin anabolism				MetaCyc:THISYN-PWY									biological_process											owl:Class	
GO:0001217	biolink:NamedThing	DNA-binding transcription repressor activity	A DNA-binding transcription factor activity that represses or decreases the transcription of specific gene sets.	tmpzr1t_l9r_go_relaxed.owl	transcriptional repressor activity, bacterial-type RNA polymerase core promoter proximal region sequence-specific binding|bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding|sequence-specific DNA binding bacterial-type RNA polymerase transcription factor activity involved in negative regulation of transcription|metal ion regulated sequence-specific DNA binding bacterial-type RNA polymerase transcription factor activity involved in negative regulation of transcription|transcriptional repressor activity, bacterial-type RNA polymerase proximal promoter sequence-specific DNA binding|bacterial-type DNA binding transcription repressor activity|cadmium ion regulated sequence-specific DNA binding bacterial-type RNA polymerase transcription factor activity involved in negative regulation of transcription|copper ion regulated sequence-specific DNA binding bacterial-type RNA polymerase transcription factor activity involved in negative regulation of transcription|bacterial-type RNA polymerase transcriptional repressor activity, copper ion regulated sequence-specific DNA binding|bacterial-type RNA polymerase transcriptional repressor activity, metal ion regulated sequence-specific DNA binding|bacterial-type RNA polymerase transcriptional repressor activity, cadmium ion regulated sequence-specific DNA binding|bacterial-type RNA polymerase core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription	https://github.com/geneontology/go-ontology/issues/16736|https://github.com/geneontology/go-ontology/issues/20253				For usage guidance, see comment in GO:0003700 ; DNA-binding transcription factor activity.		krc	2011-01-26T03:15:45Z			GO:0001219|GO:0001141|GO:0001218|GO:0001220		molecular_function											owl:Class	
GO:1903901	biolink:NamedThing	negative regulation of viral life cycle	Any process that stops, prevents or reduces the frequency, rate or extent of viral life cycle.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of viral assembly, maturation, egress, and release|down regulation of viral replication|down-regulation of viral replication|negative regulation of lytic viral life cycle|down-regulation of viral infectious cycle|down regulation of viral assembly, maturation, egress, and release|downregulation of viral infectious cycle|inhibition of viral life cycle|down-regulation of lytic viral life cycle|inhibition of viral assembly, maturation, egress, and release|downregulation of lytic viral life cycle|down-regulation of viral life cycle|downregulation of viral replication|inhibition of viral infectious cycle|down regulation of viral life cycle|down-regulation of viral assembly, maturation, egress, and release|downregulation of viral life cycle|inhibition of lytic viral life cycle|negative regulation of viral replication|negative regulation of viral infectious cycle|downregulation of viral assembly, maturation, egress, and release|down regulation of lytic viral life cycle|inhibition of viral replication|down regulation of viral infectious cycle							pga	2015-02-09T10:22:16Z					biological_process											owl:Class	
GO:0060407	biolink:NamedThing	negative regulation of penile erection	Any process that stops, prevents, or reduces the rate, frequency or extent of penile erection. Penile erection is the hardening, enlarging and rising of the penis which often occurs in the sexually aroused male and enables sexual intercourse. Achieved by increased inflow of blood into the vessels of erectile tissue, and decreased outflow.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0002720	biolink:NamedThing	positive regulation of cytokine production involved in immune response	Any process that activates or increases the frequency, rate, or extent of cytokine production that contributes to an immune response.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of cytokine production during immune response|positive regulation of cytokine production during immune response|stimulation of cytokine production during immune response|upregulation of cytokine production during immune response|up regulation of cytokine production during immune response|positive regulation of cytokine biosynthetic process involved in immune response|positive regulation of cytokine secretion involved in immune response|activation of cytokine production during immune response											GO:0002741|GO:0002744		biological_process											owl:Class	
GO:0002718	biolink:NamedThing	regulation of cytokine production involved in immune response	Any process that modulates the frequency, rate, or extent of cytokine production that contributes to an immune response.	tmpzr1t_l9r_go_relaxed.owl	regulation of cytokine biosynthetic process involved in immune response|regulation of cytokine secretion involved in immune response|regulation of cytokine production during immune response											GO:0002742|GO:0002739		biological_process											owl:Class	
GO:0018079	biolink:NamedThing	protein halogenation	The addition of a halogen to a protein amino acid.	tmpzr1t_l9r_go_relaxed.owl	protein amino acid halogenation													biological_process											owl:Class	
GO:0070276	biolink:NamedThing	halogen metabolic process	The chemical reactions and pathways involving any halogen, elements of Group VII; includes metabolism of halogen-containing compounds.	tmpzr1t_l9r_go_relaxed.owl	halogen metabolism													biological_process											owl:Class	
GO:0017058	biolink:NamedThing	FH1 domain binding	Binding to a FH1 domain of a protein, a proline-rich domain, usually located in front of a FH2 domain.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:2000376	biolink:NamedThing	positive regulation of oxygen metabolic process	Any process that activates or increases the frequency, rate or extent of oxygen metabolic process.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of oxygen metabolism|positive regulation of diatomic oxygen metabolic process							mah	2011-02-11T02:03:52Z					biological_process											owl:Class	
GO:0033069	biolink:NamedThing	ansamycin metabolic process	The chemical reactions and pathways involving ansamycins, any of a group of complex macrolactam compounds characterized by a cyclic structure in which an aliphatic ansa chain forms a bridge between two non-adjacent positions of a cyclic p-system; many exhibit antibacterial, antifungal or antitumor activity.	tmpzr1t_l9r_go_relaxed.owl	ansamycin metabolism													biological_process											owl:Class	
GO:0006748	biolink:NamedThing	lipoamide metabolic process	The chemical reactions and pathways involving lipoamide, the functional form of lipoic acid in which the carboxyl group is attached to protein by an amide linkage to a lysine amino group.	tmpzr1t_l9r_go_relaxed.owl	lipoamide metabolism													biological_process											owl:Class	
GO:1905376	biolink:NamedThing	negative regulation of cytochrome-c oxidase activity	Any process that stops, prevents or reduces the frequency, rate or extent of cytochrome-c oxidase activity.	tmpzr1t_l9r_go_relaxed.owl	inhibition of NADH cytochrome c oxidase|downregulation of complex IV (mitochondrial electron transport) activity|down regulation of cytochrome-c oxidase activity|down-regulation of complex IV (mitochondrial electron transport) activity|down-regulation of indophenol oxidase|inhibition of aa3-type cytochrome c oxidase|inhibition of ferrocytochrome c oxidase|downregulation of cytochrome aa3 activity|inhibition of cytochrome-c oxidase activity|down regulation of aa3-type cytochrome c oxidase|inhibition of cytochrome aa3 activity|down regulation of complex IV (mitochondrial electron transport) activity|down regulation of warburg's respiratory enzyme activity|downregulation of cytochrome-c oxidase activity|down regulation of indophenol oxidase|down-regulation of ba3-type cytochrome c oxidase|down regulation of cbb3-type cytochrome c oxidase|inhibition of ferrocytochrome-c:oxygen oxidoreductase|down-regulation of cytochrome-c oxidase activity|negative regulation of indophenolase|down regulation of ba3-type cytochrome c oxidase|downregulation of indophenolase|negative regulation of cytochrome oxidase activity|down-regulation of cytochrome aa3 activity|inhibition of cytochrome oxidase activity|negative regulation of ferrocytochrome c oxidase|down regulation of cytochrome oxidase activity|down regulation of indophenolase|inhibition of cbb3-type cytochrome c oxidase|inhibition of cytochrome a3 activity|down-regulation of cbb3-type cytochrome c oxidase|downregulation of indophenol oxidase|down-regulation of aa3-type cytochrome c oxidase|inhibition of complex IV (mitochondrial electron transport) activity|inhibition of indophenolase|inhibition of ba3-type cytochrome c oxidase|down regulation of cytochrome c oxidase activity|downregulation of ferrocytochrome-c:oxygen oxidoreductase|inhibition of indophenol oxidase|downregulation of warburg's respiratory enzyme activity|down regulation of ferrocytochrome c oxidase|inhibition of cytochrome c oxidase activity|downregulation of aa3-type cytochrome c oxidase|down-regulation of cytochrome a3 activity|negative regulation of cytochrome c oxidase activity|negative regulation of complex IV (mitochondrial electron transport) activity|down-regulation of caa3-type cytochrome c oxidase|down regulation of caa3-type cytochrome c oxidase|down-regulation of cytochrome oxidase activity|negative regulation of cytochrome aa3 activity|negative regulation of warburg's respiratory enzyme activity|negative regulation of cytochrome a3 activity|downregulation of ferrocytochrome c oxidase|negative regulation of caa3-type cytochrome c oxidase|down-regulation of indophenolase|downregulation of cytochrome a3 activity|down regulation of ferrocytochrome-c:oxygen oxidoreductase|down regulation of cytochrome aa3 activity|negative regulation of ferrocytochrome-c:oxygen oxidoreductase|negative regulation of ba3-type cytochrome c oxidase|inhibition of caa3-type cytochrome c oxidase|down-regulation of NADH cytochrome c oxidase|negative regulation of NADH cytochrome c oxidase|downregulation of cytochrome c oxidase activity|down regulation of NADH cytochrome c oxidase|downregulation of caa3-type cytochrome c oxidase|down-regulation of warburg's respiratory enzyme activity|downregulation of cbb3-type cytochrome c oxidase|downregulation of NADH cytochrome c oxidase|downregulation of cytochrome oxidase activity|downregulation of ba3-type cytochrome c oxidase|negative regulation of indophenol oxidase|down regulation of cytochrome a3 activity|down-regulation of cytochrome c oxidase activity|negative regulation of cbb3-type cytochrome c oxidase|negative regulation of aa3-type cytochrome c oxidase|down-regulation of ferrocytochrome c oxidase|inhibition of warburg's respiratory enzyme activity|down-regulation of ferrocytochrome-c:oxygen oxidoreductase							sl	2016-08-17T20:29:57Z					biological_process											owl:Class	
GO:1900068	biolink:NamedThing	negative regulation of cellular response to alkaline pH	Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to alkalinity.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of cellular response to basic pH|negative regulation of cellular response to alkalinity|downregulation of cellular response to alkalinity|down-regulation of cellular response to basic pH|down regulation of cellular response to basic pH|inhibition of cellular response to basic pH|down-regulation of cellular response to alkaline pH|downregulation of cellular response to basic pH|downregulation of cellular response to alkaline pH|down regulation of cellular response to alkaline pH|down regulation of cellular response to alkalinity|inhibition of cellular response to alkalinity|down-regulation of cellular response to alkalinity|inhibition of cellular response to alkaline pH							pr	2012-01-26T02:35:03Z					biological_process											owl:Class	
GO:0052591	biolink:NamedThing	sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity	Catalysis of the reaction: sn-glycerol 3-phosphate + ubiquinone-8 = glycerone phosphate + ubiquinol-8.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:GLYC3PDEHYDROG-RXN|RHEA:28751|EC:1.1.5.3	Note that enzymes classified as EC:1.1.5.3 have several activities. They should be annotated with the terms GO:0004368, GO:0052590 and GO:0052591.								molecular_function											owl:Class	
GO:0052590	biolink:NamedThing	sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity	Catalysis of the reaction: sn-glycerol 3-phosphate + a ubiquinone = glycerone phosphate + a ubiquinol.	tmpzr1t_l9r_go_relaxed.owl					EC:1.1.5.3|MetaCyc:RXN0-5258	Note that enzymes classified as EC:1.1.5.3 have several activities. They should be annotated with the terms GO:0004368, GO:0052590 and GO:0052591.								molecular_function											owl:Class	
GO:2000765	biolink:NamedThing	regulation of cytoplasmic translation	Any process that modulates the frequency, rate or extent of cytoplasmic translation.	tmpzr1t_l9r_go_relaxed.owl								vw	2011-06-20T10:39:19Z					biological_process											owl:Class	
GO:2000870	biolink:NamedThing	regulation of progesterone secretion	Any process that modulates the frequency, rate or extent of progesterone secretion.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-07-26T08:51:14Z					biological_process											owl:Class	
GO:1900788	biolink:NamedThing	pseurotin A metabolic process	The chemical reactions and pathways involving pseurotin A.	tmpzr1t_l9r_go_relaxed.owl	Pseurotin metabolism|Pseurotin metabolic process|pseurotin A metabolism							di	2012-06-04T09:37:18Z					biological_process											owl:Class	
GO:0042129	biolink:NamedThing	regulation of T cell proliferation	Any process that modulates the frequency, rate or extent of T cell proliferation.	tmpzr1t_l9r_go_relaxed.owl	regulation of T-lymphocyte proliferation|regulation of T lymphocyte proliferation|regulation of T-cell proliferation													biological_process											owl:Class	
GO:0050670	biolink:NamedThing	regulation of lymphocyte proliferation	Any process that modulates the frequency, rate or extent of lymphocyte proliferation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0075018	biolink:NamedThing	positive regulation of appressorium formation	Any process that activates or increases the frequency, rate or extent of symbiont appressorium formation.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of appressorium formation on or near host					Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products from the symbiont involved in this process.								biological_process											owl:Class	
GO:0075017	biolink:NamedThing	regulation of appressorium formation	Any process that modulates the frequency, rate or extent of symbiont appressorium formation.	tmpzr1t_l9r_go_relaxed.owl	regulation of appressorium formation on or near host													biological_process											owl:Class	
GO:1903863	biolink:NamedThing	P granule assembly	The aggregation, arrangement and bonding together of a set of components to form a P granule.	tmpzr1t_l9r_go_relaxed.owl	germline granule assembly|P granule formation|polar granule formation|germline granule formation|polar granule assembly							kmv	2015-02-04T15:27:02Z					biological_process											owl:Class	
GO:0030719	biolink:NamedThing	P granule organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of polar granules, cytoplasmic, non-membranous RNA/protein complex aggregates in the primordial germ cells of many higher eukaryotes.	tmpzr1t_l9r_go_relaxed.owl	polar granule organisation|P granule organization and biogenesis|polar granule organization and biogenesis											GO:0048114		biological_process											owl:Class	
GO:0008612	biolink:NamedThing	peptidyl-lysine modification to peptidyl-hypusine	The modification of peptidyl-lysine to form hypusine, peptidyl-N6-(4-amino-2-hydroxybutyl)-L-lysine.	tmpzr1t_l9r_go_relaxed.owl	hypusine biosynthetic process from peptidyl-lysine|hypusine synthesis from peptidyl-lysine|hypusine biosynthesis|hypusinylation|hypusine anabolism from peptidyl-lysine|hypusine formation from peptidyl-lysine|hypusine formation|hypusine biosynthetic process|protein hypusination|hypusine anabolism|hypusine synthesis				RESID:AA0116							GO:0046515		biological_process											owl:Class	
GO:0051604	biolink:NamedThing	protein maturation	Any process leading to the attainment of the full functional capacity of a protein.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0003973	biolink:NamedThing	(S)-2-hydroxy-acid oxidase activity	Catalysis of the reaction: (S)-2-hydroxy-acid + O2 = 2-oxo acid + hydrogen peroxide.	tmpzr1t_l9r_go_relaxed.owl	L-alpha-hydroxy acid oxidase|L-2-hydroxy acid oxidase|hydroxyacid oxidase A|very-long-chain-(S)-2-hydroxy-acid oxidase activity|hydroxy-acid oxidase A activity|medium-chain-(S)-2-hydroxy-acid oxidase activity|glycolate oxidase activity|long-chain-(S)-2-hydroxy-long-chain-acid oxidase activity|hydroxy-acid oxidase B activity	https://github.com/geneontology/go-ontology/issues/21795			MetaCyc:S-2-HYDROXY-ACID-OXIDASE-RXN|Reactome:R-HSA-6787811|MetaCyc:RXN-969|RHEA:16789|EC:1.1.3.15|Reactome:R-HSA-389842							GO:0052853|GO:0008891|GO:0052852|GO:0052854		molecular_function											owl:Class	
GO:0050071	biolink:NamedThing	lysyltransferase activity	Catalysis of the reaction: L-lysyl-tRNA + phosphatidylglycerol = tRNA + 3-phosphatidyl-1'-(3'-O-L-lysyl)glycerol.	tmpzr1t_l9r_go_relaxed.owl	L-lysyl-tRNA:phosphatidylglycerol O3-lysyltransferase activity|L-lysyl-tRNA:phosphatidylglycerol 3-O-lysyltransferase activity				EC:2.3.2.3|MetaCyc:LYSYLTRANSFERASE-RXN|RHEA:10668									molecular_function											owl:Class	
GO:0030203	biolink:NamedThing	glycosaminoglycan metabolic process	The chemical reactions and pathways involving glycosaminoglycans, any of a group of polysaccharides that contain amino sugars.	tmpzr1t_l9r_go_relaxed.owl	glycosaminoglycan metabolism													biological_process											owl:Class	
GO:0046933	biolink:NamedThing	proton-transporting ATP synthase activity, rotational mechanism	Enables the synthesis of ATP from ADP and phosphate by the transfer of protons from one side of a membrane to the other by a rotational mechanism driven by a gradient according to the reaction: ADP + H2O + phosphate + H+(in) -> ATP + H+(out).	tmpzr1t_l9r_go_relaxed.owl	hydrogen ion transporting two-sector ATPase activity|H+-transporting ATP synthase activity|hydrogen ion translocating F-type ATPase activity|hydrogen ion transporting ATP synthase activity, rotational mechanism	https://github.com/geneontology/go-ontology/issues/19380			MetaCyc:ATPSYN-RXN|Reactome:R-HSA-164832|EC:7.1.2.2|TC:3.A.2.1.1|RHEA:57720									molecular_function											owl:Class	
GO:0050978	biolink:NamedThing	magnetoreception by sensory perception of electrical stimulus	The series of events required for an organism to receive an electrical stimulus relating to a magnetic field, convert it to a molecular signal, and recognize and characterize the signal. Movement in a magnetic field results in an induced electric field, which can be perceived by organisms such as elasmobranch fish.	tmpzr1t_l9r_go_relaxed.owl	magnetoreception, sensory perception of electrical stimulus|magnetoreception through electrical stimulus|magnetoreception by electrical stimulus|magnetoreception, using electrical stimulus													biological_process											owl:Class	
GO:0050952	biolink:NamedThing	sensory perception of electrical stimulus	The series of events required for an organism to receive a sensory electrical stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0047091	biolink:NamedThing	L-lysine 6-monooxygenase (NADPH) activity	Catalysis of the reaction: L-lysine + NADPH + O(2) = N(6)-hydroxy-L-lysine + H(2)O + NADP(+).	tmpzr1t_l9r_go_relaxed.owl	L-lysine 6-monooxygenase activity|L-lysine,NADPH:oxygen oxidoreductase (6-hydroxylating)|lysine N(6)-hydroxylase activity|lysine N6-hydroxylase activity				EC:1.14.13.59|KEGG_REACTION:R00448|RHEA:23228|MetaCyc:1.14.13.59-RXN	Note that EC:1.13.12.10 was merged into this term.						GO:0008739		molecular_function											owl:Class	
GO:1900433	biolink:NamedThing	positive regulation of filamentous growth of a population of unicellular organisms in response to heat	Any process that activates or increases the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to heat.	tmpzr1t_l9r_go_relaxed.owl	up regulation of filamentous growth of a population of unicellular organisms in response to heat|upregulation of filamentous growth of a population of unicellular organisms in response to heat|up-regulation of filamentous growth of a population of unicellular organisms in response to heat|activation of filamentous growth of a population of unicellular organisms in response to heat							di	2012-04-25T05:54:23Z					biological_process											owl:Class	
GO:1900431	biolink:NamedThing	regulation of filamentous growth of a population of unicellular organisms in response to heat	Any process that modulates the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to heat.	tmpzr1t_l9r_go_relaxed.owl								di	2012-04-25T05:54:05Z					biological_process											owl:Class	
GO:0019676	biolink:NamedThing	ammonia assimilation cycle	The pathway by which ammonia is processed and incorporated into a cell. In an energy-rich (glucose-containing), nitrogen-poor environment, glutamine synthetase and glutamate synthase form an ammonia assimilatory cycle, in which ammonia is incorporated into L-glutamate to form L-glutamine, which then combines with alpha-ketoglutarate to regenerate L-glutamate. This ATP-dependent cycle is essential for nitrogen-limited growth and for steady-state growth with some sources of nitrogen.	tmpzr1t_l9r_go_relaxed.owl	glutamate metabolic process via glutamine and ammonia|glutamate metabolism via glutamine and ammonia				MetaCyc:PWY-3282|MetaCyc:AMMASSIM-PWY									biological_process											owl:Class	
GO:0006541	biolink:NamedThing	glutamine metabolic process	The chemical reactions and pathways involving glutamine, 2-amino-4-carbamoylbutanoic acid.	tmpzr1t_l9r_go_relaxed.owl	glutamine metabolism													biological_process											owl:Class	
GO:1900592	biolink:NamedThing	violaceol II catabolic process	The chemical reactions and pathways resulting in the breakdown of violaceol II.	tmpzr1t_l9r_go_relaxed.owl	violaceol II catabolism|violaceol II breakdown|violaceol II degradation							di	2012-05-15T06:51:43Z					biological_process											owl:Class	
GO:1900591	biolink:NamedThing	violaceol II metabolic process	The chemical reactions and pathways involving violaceol II.	tmpzr1t_l9r_go_relaxed.owl	violaceol II metabolism							di	2012-05-15T06:51:21Z					biological_process											owl:Class	
GO:0034284	biolink:NamedThing	response to monosaccharide	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monosaccharide stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to monosaccharide stimulus													biological_process											owl:Class	
GO:0009743	biolink:NamedThing	response to carbohydrate	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbohydrate stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to carbohydrate stimulus													biological_process											owl:Class	
GO:0039003	biolink:NamedThing	pronephric field specification	The process in which regions of the embryo are delineated into the area in which the pronephric kidney will develop.	tmpzr1t_l9r_go_relaxed.owl	pronephric kidney field specification							bf	2010-07-02T09:28:16Z					biological_process											owl:Class	
GO:0039017	biolink:NamedThing	pattern specification involved in pronephros development	Any developmental process that results in the creation of defined areas or spaces within the pronephros to which cells respond and eventually are instructed to differentiate.	tmpzr1t_l9r_go_relaxed.owl	pattern specification involved in pronephric kidney development							bf	2010-07-02T10:04:39Z					biological_process											owl:Class	
GO:2001038	biolink:NamedThing	regulation of cellular response to drug	Any process that modulates the frequency, rate or extent of cellular response to drug.	tmpzr1t_l9r_go_relaxed.owl								yaf	2011-08-27T04:12:19Z					biological_process											owl:Class	
GO:0006356	biolink:NamedThing	regulation of transcription by RNA polymerase I	Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase I.	tmpzr1t_l9r_go_relaxed.owl	regulation of transcription from Pol I promoter|regulation of transcription from RNA polymerase I promoter													biological_process											owl:Class	
GO:0018608	biolink:NamedThing	1-indanone dioxygenase activity	Catalysis of the reaction: 1-indanone + NADPH + 1/2 O2 = NADP+ + 3-hydroxy-1-indanone.	tmpzr1t_l9r_go_relaxed.owl					EC:1.14.12.-|UM-BBD_reactionID:r0416									molecular_function											owl:Class	
GO:0045476	biolink:NamedThing	nurse cell apoptotic process	Any apoptotic process in a nurse cell. During late oogenesis, following the transfer of substances from the nurse cells to the oocyte, nurse cell remnants are cleared from the egg chamber by apoptotic process.	tmpzr1t_l9r_go_relaxed.owl	nurse cell programmed cell death by apoptosis|nurse cell apoptosis|programmed cell death of nurse cells by apoptosis|invertebrate nurse cell apoptosis|apoptosis of nurse cells													biological_process											owl:Class	
GO:0071684	biolink:NamedThing	organism emergence from protective structure	The developmental process in which an organism emerges from a surrounding protective structure such as an egg or pupa case.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-02-19T04:23:55Z					biological_process											owl:Class	
GO:0018845	biolink:NamedThing	2-hydroxychromene-2-carboxylate isomerase activity	Catalysis of the reaction: 2-hydroxychromene-2-carboxylate = (3E)-4-(2-hydroxyphenyl)-2-oxobut-3-enoate. (3E)-4-(2-hydroxyphenyl)-2-oxobut-3-enoate is also known as trans-o-hydroxybenzylidenepyruvate.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXNN-386|RHEA:27401|UM-BBD_reactionID:r0337|EC:5.99.1.4|KEGG_REACTION:R05137									molecular_function											owl:Class	
GO:0022015	biolink:NamedThing	radial glial cell division in pallium	The division of a radial glial cell in the pallium. A radial glial cell is a precursor cell that gives rise to neurons and astrocytes.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0051363	biolink:NamedThing	peptidoglycan-protein cross-linking via L-alanyl-pentaglycyl-murein	The process of linking a protein to peptidoglycan via a carboxy terminal alanine carboxyl group through a pentaglycyl peptide to the lysine or diaminopimelic acid of the peptidoglycan.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0383	Note that this modification may be unique to the species Finegoldia (Peptostreptococcus) magnus.								biological_process											owl:Class	
GO:0018104	biolink:NamedThing	peptidoglycan-protein cross-linking	The process of covalently linking peptidoglycan (murein) to proteins.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:2000641	biolink:NamedThing	regulation of early endosome to late endosome transport	Any process that modulates the frequency, rate or extent of early endosome to late endosome transport.	tmpzr1t_l9r_go_relaxed.owl								vk	2011-04-21T11:20:02Z					biological_process											owl:Class	
GO:0080141	biolink:NamedThing	regulation of jasmonic acid biosynthetic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of jasmonic acid.	tmpzr1t_l9r_go_relaxed.owl								dhl	2009-05-19T04:28:39Z					biological_process											owl:Class	
GO:0000123	biolink:NamedThing	histone acetyltransferase complex	A protein complex that possesses histone acetyltransferase activity.	tmpzr1t_l9r_go_relaxed.owl	histone acetylase complex					Note that this term represents a location, not a function; the activity possessed by this complex is mentioned in the definition for the purpose of describing and distinguishing the complex. The function of this complex is represented by the molecular function term 'histone acetyltransferase activity ; GO:0004402'.								cellular_component											owl:Class	
GO:0034233	biolink:NamedThing	regulation of cell wall chitin catabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of cell wall chitin.	tmpzr1t_l9r_go_relaxed.owl	regulation of cell wall chitin breakdown|regulation of cell wall chitin catabolism|regulation of cell wall chitin degradation													biological_process											owl:Class	
GO:0034222	biolink:NamedThing	regulation of cell wall chitin metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving chitin in a cell wall.	tmpzr1t_l9r_go_relaxed.owl	regulation of cell wall chitin metabolism													biological_process											owl:Class	
GO:0044069	biolink:NamedThing	modulation by symbiont of host anion transport	The process in which a symbiont organism modulates the anion transport, the directed movement of anions, atoms or small molecules with a net negative charge, into, out of or within a cell, or between cells, of its host organism.	tmpzr1t_l9r_go_relaxed.owl	modification of host anion transport by symbiont													biological_process											owl:Class	
GO:1903401	biolink:NamedThing	L-lysine transmembrane transport	The directed movement of L-lysine across a membrane.	tmpzr1t_l9r_go_relaxed.owl								pr	2014-09-01T13:45:56Z					biological_process											owl:Class	
GO:1902475	biolink:NamedThing	L-alpha-amino acid transmembrane transport	The directed movement of L-alpha-amino acid across a membrane.	tmpzr1t_l9r_go_relaxed.owl								kmv	2013-10-25T15:17:39Z					biological_process											owl:Class	
GO:1990049	biolink:NamedThing	retrograde neuronal dense core vesicle transport	The directed movement of neuronal dense core vesicles along axonal microtubules towards the cell body.	tmpzr1t_l9r_go_relaxed.owl	retrograde dense core granule transport|retrograde dense core granule trafficking							pr	2013-02-19T13:31:44Z					biological_process											owl:Class	
GO:0008090	biolink:NamedThing	retrograde axonal transport	The directed movement of organelles or molecules along microtubules from the cell periphery toward the cell body in nerve cell axons.	tmpzr1t_l9r_go_relaxed.owl	retrograde axon cargo transport													biological_process											owl:Class	
GO:0071671	biolink:NamedThing	regulation of smooth muscle cell chemotaxis	Any process that modulates the frequency, rate, or extent of smooth muscle cell chemotaxis.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-02-16T01:42:03Z					biological_process											owl:Class	
GO:0102999	biolink:NamedThing	UDP-glucose:2-hydroxylamino-4,6-dinitrotoluene-O-glucosyltransferase activity	Catalysis of the reaction: UDP-alpha-D-glucose + 2-hydroxylamino-4,6-dinitrotoluene <=> 2-hydroxylamino-4,6-dinitrotoluene-O-glucoside + UDP + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-9743									molecular_function											owl:Class	
GO:0042472	biolink:NamedThing	inner ear morphogenesis	The process in which the anatomical structures of the inner ear are generated and organized. The inner ear is the structure in vertebrates that contains the organs of balance and hearing. It consists of soft hollow sensory structures (the membranous labyrinth) containing fluid (endolymph) surrounded by fluid (perilymph) and encased in a bony cavity (the bony labyrinth). It consists of two chambers, the sacculus and utriculus, from which arise the cochlea and semicircular canals respectively.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0009232	biolink:NamedThing	riboflavin catabolic process	The chemical reactions and pathways resulting in the breakdown of riboflavin (vitamin B2), the precursor for the coenzymes flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD).	tmpzr1t_l9r_go_relaxed.owl	riboflavin breakdown|vitamin G catabolism|riboflavin catabolism|vitamin B2 catabolic process|riboflavin degradation|vitamin G catabolic process|vitamin B2 catabolism													biological_process											owl:Class	
GO:0031439	biolink:NamedThing	positive regulation of mRNA cleavage	Any process that activates or increases the frequency, rate or extent of mRNA cleavage.	tmpzr1t_l9r_go_relaxed.owl	upregulation of mRNA cleavage|stimulation of mRNA cleavage|up-regulation of mRNA cleavage|activation of mRNA cleavage|up regulation of mRNA cleavage													biological_process											owl:Class	
GO:1903313	biolink:NamedThing	positive regulation of mRNA metabolic process	Any process that activates or increases the frequency, rate or extent of mRNA metabolic process.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of mRNA metabolic process|up-regulation of mRNA metabolism|positive regulation of mRNA metabolism|up regulation of mRNA metabolism|activation of mRNA metabolism|activation of mRNA metabolic process|upregulation of mRNA metabolic process|upregulation of mRNA metabolism|up regulation of mRNA metabolic process							vw	2014-08-18T11:52:42Z					biological_process											owl:Class	
GO:1900796	biolink:NamedThing	terrequinone A biosynthetic process	The chemical reactions and pathways resulting in the formation of terrequinone A.	tmpzr1t_l9r_go_relaxed.owl	terrequinone A anabolism|terrequinone A biosynthesis|terrequinone A formation|terrequinone A synthesis							di	2012-06-04T09:45:48Z					biological_process											owl:Class	
GO:1904214	biolink:NamedThing	positive regulation of iodide transmembrane transport	Any process that activates or increases the frequency, rate or extent of iodide transmembrane transport.	tmpzr1t_l9r_go_relaxed.owl	up regulation of iodide transmembrane transport|upregulation of iodide transmembrane transport|activation of iodide transmembrane transport|up-regulation of iodide transmembrane transport							sl	2015-05-14T19:00:14Z					biological_process											owl:Class	
GO:1904203	biolink:NamedThing	positive regulation of iodide transport	Any process that activates or increases the frequency, rate or extent of iodide transport.	tmpzr1t_l9r_go_relaxed.owl	up regulation of iodide transport|activation of iodide transport|upregulation of iodide transport|up-regulation of iodide transport							sl	2015-05-08T15:20:09Z					biological_process											owl:Class	
GO:0002825	biolink:NamedThing	regulation of T-helper 1 type immune response	Any process that modulates the frequency, rate, or extent of a T-helper 1 type immune response.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0002128	biolink:NamedThing	tRNA nucleoside ribose methylation	The process that results in the modification of the sugar of a nucleoside in tRNA at the 2'O position.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1905380	biolink:NamedThing	regulation of snRNA transcription by RNA polymerase II	Any process that modulates the frequency, rate or extent of snRNA transcription mediated by RNA polymerase II.	tmpzr1t_l9r_go_relaxed.owl	regulation of snRNA transcription from RNA polymerase II promoter|regulation of snRNA transcription from Pol II promoter							bhm	2016-08-18T13:39:20Z					biological_process											owl:Class	
GO:0045734	biolink:NamedThing	regulation of acetate catabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of acetate, the anion of acetic acid.	tmpzr1t_l9r_go_relaxed.owl	regulation of acetate breakdown|regulation of acetate catabolism|regulation of acetate degradation													biological_process											owl:Class	
GO:0002258	biolink:NamedThing	positive regulation of kinin cascade	Any process that activates or increases the frequency, rate, or extent of the kinin cascade.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of kinin cascade|stimulation of kinin cascade|up regulation of kinin cascade|upregulation of kinin cascade|activation of kinin cascade													biological_process											owl:Class	
GO:0050624	biolink:NamedThing	vomilenine reductase activity	Catalysis of the reaction: 1,2-dihydrovomilenine + NADP(+) = H(+) + NADPH + vomilenine.	tmpzr1t_l9r_go_relaxed.owl	1,2-dihydrovomilenine:NADP+ oxidoreductase activity				RHEA:16409|EC:1.5.1.32|MetaCyc:1.5.1.32-RXN|KEGG_REACTION:R05878									molecular_function											owl:Class	
GO:0071463	biolink:NamedThing	cellular response to humidity	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a humidity stimulus, moisture in the atmosphere.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-12-18T11:33:55Z					biological_process											owl:Class	
GO:0009270	biolink:NamedThing	response to humidity	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a humidity stimulus, moisture in the atmosphere.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0086072	biolink:NamedThing	AV node cell-bundle of His cell adhesion involved in cell communication	The attachment of an AV node cell to an bundle of His cell via adhesion molecules that results in the cells being juxtaposed so that they can communicate.	tmpzr1t_l9r_go_relaxed.owl	atrioventricular node cell-bundle of His cell adhesion involved in cell communication							dph	2011-11-22T09:49:59Z					biological_process											owl:Class	
GO:0086042	biolink:NamedThing	cardiac muscle cell-cardiac muscle cell adhesion	The attachment of one cardiomyocyte to another cardiomyocyte via adhesion molecules.	tmpzr1t_l9r_go_relaxed.owl	cardiomyocyte-cardiomyocyte adhesion							tb	2011-11-11T04:06:25Z					biological_process											owl:Class	
GO:0031384	biolink:NamedThing	regulation of initiation of mating projection growth	Any process that modulates the frequency, rate, or extent of the start of mating projection formation by unicellular fungi.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0031383	biolink:NamedThing	regulation of mating projection assembly	Any process that modulates the frequency, rate, or extent of mating projection formation by unicellular fungi.	tmpzr1t_l9r_go_relaxed.owl	regulation of mating projection biogenesis													biological_process											owl:Class	
GO:1990761	biolink:NamedThing	growth cone lamellipodium	A thin sheetlike process extended by the leading edge of an axonal or dendritic growth cone; contains a dense meshwork of actin filaments.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-06-05T22:31:19Z					cellular_component											owl:Class	
GO:0140405	biolink:NamedThing	spindle pole body-led chromosome movement during mitotic interphase	A microtubule-based process in which chromosomes migrate as a result of rapid spindle pole body (SPB) and centrosome oscillations during mitotic interphase.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/19149|https://github.com/geneontology/go-ontology/issues/18373						pg	2019-12-10T09:13:47Z					biological_process											owl:Class	
GO:0007018	biolink:NamedThing	microtubule-based movement	A microtubule-based process that results in the movement of organelles, other microtubules, or other cellular components.  Examples include motor-driven movement along microtubules and movement driven by polymerization or depolymerization of microtubules.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0070762	biolink:NamedThing	nuclear pore transmembrane ring	A subcomplex of the nuclear pore complex (NPC) that spans the nuclear membrane and anchors the NPC to the nuclear envelope. In S. cerevisiae, the transmembrane ring is composed of Pom152p, Pom34p, and Ndc1p. In vertebrates, it is composed of Gp210, Ndc1, and Pom121. Components are arranged in 8-fold symmetrical 'spokes' around the central transport channel. A single 'spoke', can be isolated and is sometime referred to as the Ndc1 complex.	tmpzr1t_l9r_go_relaxed.owl	NDC1 subcomplex|NDC1 complex							mah	2009-06-29T11:02:56Z					cellular_component											owl:Class	
GO:1902951	biolink:NamedThing	negative regulation of dendritic spine maintenance	Any process that stops, prevents or reduces the frequency, rate or extent of dendritic spine maintenance.	tmpzr1t_l9r_go_relaxed.owl	down regulation of dendritic spine maintenance|downregulation of dendritic spine maintenance|down-regulation of dendritic spine maintenance|inhibition of dendritic spine maintenance							sjp	2014-05-02T08:48:53Z					biological_process											owl:Class	
GO:0015121	biolink:NamedThing	phosphoenolpyruvate:phosphate antiporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: phosphoenolpyruvate(out) + phosphate(in) = phosphoenolpyruvate(in) + phosphate(out).	tmpzr1t_l9r_go_relaxed.owl	phosphoenolpyruvate/phosphate translocator|PPT													molecular_function											owl:Class	
GO:0015315	biolink:NamedThing	organophosphate:inorganic phosphate antiporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: organophosphate(out) + inorganic phosphate(in) = organophosphate(in) + inorganic phosphate(out).	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0019628	biolink:NamedThing	urate catabolic process	The chemical reactions and pathways resulting in the breakdown of urate, the anion of uric acid, 2,6,8-trioxypurine.	tmpzr1t_l9r_go_relaxed.owl	urate catabolism|uric acid catabolic process|urate degradation|urate breakdown				MetaCyc:P165-PWY									biological_process											owl:Class	
GO:0051523	biolink:NamedThing	cell growth mode switching, monopolar to bipolar	The process in which a cell switches from monopolar cell growth to bipolar cell growth.	tmpzr1t_l9r_go_relaxed.owl	NETO|new end take off													biological_process											owl:Class	
GO:0061389	biolink:NamedThing	regulation of direction of cell growth	Any process that modulates the direction of cell growth.	tmpzr1t_l9r_go_relaxed.owl								dph	2011-07-14T10:19:46Z					biological_process											owl:Class	
GO:1900818	biolink:NamedThing	ochratoxin A biosynthetic process	The chemical reactions and pathways resulting in the formation of ochratoxin A.	tmpzr1t_l9r_go_relaxed.owl	Ochratoxin A biosynthesis|Ochratoxin A anabolism|Ochratoxin A synthesis|Ochratoxin A formation							di	2012-06-04T10:13:32Z					biological_process											owl:Class	
GO:1905555	biolink:NamedThing	positive regulation of blood vessel branching	Any process that activates or increases the frequency, rate or extent of blood vessel branching.	tmpzr1t_l9r_go_relaxed.owl	up regulation of branching involved in blood vessel morphogenesis|upregulation of patterning of blood vessels|activation of branching involved in blood vessel morphogenesis|up regulation of patterning of blood vessels|up-regulation of branching involved in blood vessel morphogenesis|up-regulation of patterning of blood vessels|upregulation of branching involved in blood vessel morphogenesis|activation of patterning of blood vessels|positive regulation of branching involved in blood vessel morphogenesis							nc	2016-10-12T14:19:49Z					biological_process											owl:Class	
GO:1905553	biolink:NamedThing	regulation of blood vessel branching	Any process that modulates the frequency, rate or extent of blood vessel branching.	tmpzr1t_l9r_go_relaxed.owl	regulation of branching involved in blood vessel morphogenesis							nc	2016-10-12T14:19:33Z					biological_process											owl:Class	
GO:0051105	biolink:NamedThing	regulation of DNA ligation	Any process that modulates the frequency, rate or extent of DNA ligation, the re-formation of a broken phosphodiester bond in the DNA backbone, carried out by DNA ligase.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1990770	biolink:NamedThing	small intestine smooth muscle contraction	A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry in the intestine between the stomach and the large intestine.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-06-11T18:02:33Z					biological_process											owl:Class	
GO:0046251	biolink:NamedThing	limonene catabolic process	The chemical reactions and pathways resulting in the breakdown of limonene (4-isopropenyl-1-methyl-cyclohexene), a monocyclic monoterpene.	tmpzr1t_l9r_go_relaxed.owl	limonene catabolism|limonene degradation|limonene breakdown													biological_process											owl:Class	
GO:0048780	biolink:NamedThing	positive regulation of erythrophore differentiation	Any process that activates or increases the frequency, rate or extent of erythrophore differentiation.	tmpzr1t_l9r_go_relaxed.owl	stimulation of erythrophore differentiation|upregulation of erythrophore differentiation|activation of erythrophore differentiation|up-regulation of erythrophore differentiation|up regulation of erythrophore differentiation													biological_process											owl:Class	
GO:0048778	biolink:NamedThing	regulation of erythrophore differentiation	Any process that modulates the frequency, rate or extent of erythrophore differentiation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1900005	biolink:NamedThing	positive regulation of serine-type endopeptidase activity	Any process that activates or increases the frequency, rate or extent of serine-type endopeptidase activity.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of blood coagulation factor activity|up regulation of blood coagulation factor activity|up regulation of serine-type endopeptidase activity							kmv	2012-01-09T10:03:29Z					biological_process											owl:Class	
GO:1900003	biolink:NamedThing	regulation of serine-type endopeptidase activity	Any process that modulates the frequency, rate or extent of serine-type endopeptidase activity.	tmpzr1t_l9r_go_relaxed.owl	regulation of blood coagulation factor activity							kmv	2012-01-09T10:03:15Z					biological_process											owl:Class	
GO:1902865	biolink:NamedThing	positive regulation of embryonic camera-type eye development	Any process that activates or increases the frequency, rate or extent of embryonic camera-type eye development.	tmpzr1t_l9r_go_relaxed.owl	upregulation of embryonic eye development|activation of embryonic eye development|up-regulation of embryonic camera-type eye development|activation of embryonic camera-type eye development|up-regulation of embryonic eye development|positive regulation of embryonic eye development|up regulation of embryonic eye development|up regulation of embryonic camera-type eye development|upregulation of embryonic camera-type eye development							mr	2014-04-03T15:24:12Z					biological_process											owl:Class	
GO:0010633	biolink:NamedThing	negative regulation of epithelial cell migration	Any process that stops, prevents, or reduces the frequency, rate or extent of epithelial cell migration.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1990185	biolink:NamedThing	regulation of lymphatic vascular permeability	Any process that modulates the extent to which lymphatic vessels can be pervaded by fluid.	tmpzr1t_l9r_go_relaxed.owl								sl	2013-09-11T15:36:22Z					biological_process											owl:Class	
GO:0043114	biolink:NamedThing	regulation of vascular permeability	Any process that modulates the extent to which blood vessels can be pervaded by fluid.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:2000160	biolink:NamedThing	negative regulation of planar cell polarity pathway involved in heart morphogenesis	Any process that stops, prevents, or reduces the frequency, rate or extent of planar cell polarity pathway involved in heart morphogenesis.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-10-05T01:03:25Z					biological_process											owl:Class	
GO:1904136	biolink:NamedThing	regulation of convergent extension involved in notochord morphogenesis	Any process that modulates the frequency, rate or extent of convergent extension involved in notochord morphogenesis.	tmpzr1t_l9r_go_relaxed.owl								dph	2015-04-10T21:21:30Z					biological_process											owl:Class	
GO:0060524	biolink:NamedThing	dichotomous subdivision of prostate epithelial cord terminal unit	The process in which a prostate epithelial cord bifurcates at its end.	tmpzr1t_l9r_go_relaxed.owl	prostate epithelial cord bifurcation													biological_process											owl:Class	
GO:0003271	biolink:NamedThing	smoothened signaling pathway involved in regulation of secondary heart field cardioblast proliferation	The series of molecular signals generated as a consequence of activation of the transmembrane protein Smoothened contributing to the modulation of the frequency, rate or extent of cardioblast proliferation in the secondary heart field. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.	tmpzr1t_l9r_go_relaxed.owl	hedgehog signaling pathway involved in regulation of second heart field cardioblast proliferation|smoothened receptor signalling pathway involved in regulation of secondary heart field cardioblast proliferation|hh signaling pathway involved in regulation of second heart field cardioblast proliferation|smoothened receptor signaling pathway involved in regulation of secondary heart field cardioblast proliferation|smoothened receptor signaling pathway involved in regulation of second heart field cardioblast proliferation							dph	2009-10-15T02:48:32Z					biological_process											owl:Class	
GO:0071154	biolink:NamedThing	G-protein alpha(i)1-synembrin complex	A protein complex formed by the association of the guanine nucleotide exchange factor synembrin with the alpha(i)1 subunit of a heterotrimeric G protein.	tmpzr1t_l9r_go_relaxed.owl	Ric-8A G(i) alpha-2 subunit complex|Ric-8A G(i) alpha-1 subunit complex							mah	2009-11-16T04:57:46Z					cellular_component											owl:Class	
GO:1901227	biolink:NamedThing	negative regulation of transcription from RNA polymerase II promoter involved in heart development	Any negative regulation of transcription from RNA polymerase II promoter that is involved in heart development.	tmpzr1t_l9r_go_relaxed.owl	inhibition of transcription from RNA polymerase II promoter involved in dorsal vessel development|negative regulation of transcription from Pol II promoter involved in heart development|negative regulation of global transcription from Pol II promoter involved in heart development|negative regulation of gene-specific transcription from RNA polymerase II promoter involved in dorsal vessel development|down regulation of transcription from RNA polymerase II promoter involved in dorsal vessel development|inhibition of transcription from RNA polymerase II promoter involved in cardiac development|negative regulation of global transcription from Pol II promoter involved in dorsal vessel development|downregulation of transcription from RNA polymerase II promoter involved in dorsal vessel development|down regulation of global transcription from RNA polymerase II promoter involved in heart development|negative regulation of transcription from Pol II promoter involved in dorsal vessel development|down-regulation of transcription from RNA polymerase II promoter involved in cardiac development|down regulation of transcription from RNA polymerase II promoter involved in cardiac development|downregulation of global transcription from RNA polymerase II promoter involved in cardiac development|down-regulation of global transcription from RNA polymerase II promoter involved in heart development|down-regulation of global transcription from RNA polymerase II promoter involved in cardiac development|negative regulation of transcription from RNA polymerase II promoter involved in dorsal vessel development|negative regulation of transcription from Pol II promoter involved in cardiac development|negative regulation of global transcription from Pol II promoter involved in cardiac development|downregulation of transcription from RNA polymerase II promoter involved in heart development|inhibition of transcription from RNA polymerase II promoter involved in heart development|negative regulation of gene-specific transcription from RNA polymerase II promoter involved in cardiac development|downregulation of global transcription from RNA polymerase II promoter involved in dorsal vessel development|downregulation of global transcription from RNA polymerase II promoter involved in heart development|down regulation of global transcription from RNA polymerase II promoter involved in cardiac development|inhibition of global transcription from RNA polymerase II promoter involved in heart development|down-regulation of transcription from RNA polymerase II promoter involved in heart development|inhibition of global transcription from RNA polymerase II promoter involved in cardiac development|negative regulation of gene-specific transcription from RNA polymerase II promoter involved in heart development|down regulation of global transcription from RNA polymerase II promoter involved in dorsal vessel development|downregulation of transcription from RNA polymerase II promoter involved in cardiac development|negative regulation of transcription from RNA polymerase II promoter involved in cardiac development|down-regulation of global transcription from RNA polymerase II promoter involved in dorsal vessel development|down regulation of transcription from RNA polymerase II promoter involved in heart development|down-regulation of transcription from RNA polymerase II promoter involved in dorsal vessel development|inhibition of global transcription from RNA polymerase II promoter involved in dorsal vessel development							pr	2012-08-07T12:50:30Z					biological_process											owl:Class	
GO:0008940	biolink:NamedThing	nitrate reductase activity	Catalysis of the reaction: nitrite + acceptor = nitrate + reduced acceptor.	tmpzr1t_l9r_go_relaxed.owl	nitrite:acceptor oxidoreductase|nitrite:(acceptor) oxidoreductase|nitrate reductase (acceptor)|respiratory nitrate reductase activity				RHEA:21068|MetaCyc:NITRATREDUCT-RXN|EC:1.7.99.4									molecular_function											owl:Class	
GO:1905531	biolink:NamedThing	positive regulation of uracil import across plasma membrane	Any process that activates or increases the frequency, rate or extent of uracil import across plasma membrane.	tmpzr1t_l9r_go_relaxed.owl								vw	2016-10-05T21:03:56Z					biological_process											owl:Class	
GO:1990491	biolink:NamedThing	methane biosynthetic process from methanol and hydrogen	The chemical reactions and pathways resulting in the formation of methane from methanol and hydrogen.	tmpzr1t_l9r_go_relaxed.owl	methane biosynthesis from methanol and hydrogen|methanogenesis from methanol and hydrogen							tt	2014-09-21T01:08:40Z					biological_process											owl:Class	
GO:1902421	biolink:NamedThing	hydrogen metabolic process	The chemical reactions and pathways involving H2 (dihydrogen).	tmpzr1t_l9r_go_relaxed.owl	H2 metabolism|molecular hydrogen metabolism|dihydrogen metabolism							jl	2013-09-18T14:34:23Z					biological_process											owl:Class	
GO:0018837	biolink:NamedThing	2-hydroxy-2H-benzo[h]chromene-2-carboxylate isomerase activity	Catalysis of the reaction: 2-hydroxy-2 H-benzo[h]chromene-2-carboxylate = cis -4-(1'-hydroxynaphth-2'-yl)-2-oxobut-3-enoate.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0502									molecular_function											owl:Class	
GO:0016856	biolink:NamedThing	racemase and epimerase activity, acting on hydroxy acids and derivatives	Catalysis of a reaction that alters the configuration of one or more chiral centers in a hydroxy acid molecule.	tmpzr1t_l9r_go_relaxed.owl					EC:5.1.2.-									molecular_function											owl:Class	
GO:0098845	biolink:NamedThing	postsynaptic endosome	An endosomal compartment that is part of the post-synapse. Only early and recycling endosomes are typically present in the postsynapse.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0005768	biolink:NamedThing	endosome	A vacuole to which materials ingested by endocytosis are delivered.	tmpzr1t_l9r_go_relaxed.owl					NIF_Subcellular:sao1720343330|Wikipedia:Endosome									cellular_component											owl:Class	
GO:0051310	biolink:NamedThing	metaphase plate congression	The alignment of chromosomes at the metaphase plate (spindle equator), a plane halfway between the poles of the spindle.	tmpzr1t_l9r_go_relaxed.owl	chromosome congression													biological_process											owl:Class	
GO:1904487	biolink:NamedThing	cellular response to 17alpha-ethynylestradiol	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 17alpha-ethynylestradiol stimulus.	tmpzr1t_l9r_go_relaxed.owl								mr	2015-07-15T22:31:42Z					biological_process											owl:Class	
GO:1901163	biolink:NamedThing	regulation of trophoblast cell migration	Any process that modulates the frequency, rate or extent of trophoblast cell migration.	tmpzr1t_l9r_go_relaxed.owl								vk	2012-07-19T07:53:06Z					biological_process											owl:Class	
GO:0140681	biolink:NamedThing	histone H3-tri/dimethyl-lysine-36 demethylase activity	Catalysis of the removal of a methyl group from a tri- or a dimethyl-lysine residue at position 36 of the histone H3 protein. This is a dioxygenase reaction that is dependent on Fe(II) and 2-oxoglutarate.	tmpzr1t_l9r_go_relaxed.owl	histone H3K36me3 demethylase activity|histone H3K36me2 demethylase activity	https://github.com/geneontology/go-ontology/issues/21089			RHEA:60236|EC:1.14.11.69|MetaCyc:RXN-8660			pg	2021-07-08T14:12:31Z					molecular_function											owl:Class	
GO:0051864	biolink:NamedThing	histone H3-methyl-lysine-36 demethylase activity	Catalysis of the removal of a methyl group from a modified lysine residue at position 36 of the histone H3 protein. This is a dioxygenase reaction that is dependent on Fe(II) and 2-oxoglutarate.	tmpzr1t_l9r_go_relaxed.owl	histone-lysine demethylase activity (H3-K36 specific)|histone H3K36 demethylase activity|histone demethylase activity (H3-K36 specific)|histone-lysine(H3-K36) demethylase activity|[histone-H3]-lysine-36 demethylase activity|histone H3-lysine-36 demethylase activity|histone-lysine (H3-K36) demethylase activity	https://github.com/geneontology/go-ontology/issues/21089												molecular_function											owl:Class	
GO:0008503	biolink:NamedThing	benzodiazepine receptor activity	Combining with benzodiazepines, a class of drugs with hypnotic, anxiolytic, anticonvulsive, amnestic and myorelaxant properties, to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl						Note that this term represents an activity and not a gene product. Consider also annotating to the molecular function terms 'chloride channel activity ; GO:0005254', 'GABA receptor activity ; GO:0016917' and 'inhibitory extracellular ligand-gated ion channel activity ; GO:0005237'.								molecular_function											owl:Class	
GO:0061305	biolink:NamedThing	maintenance of bipolar cell polarity regulating cell shape	The maintenance of established bipolar anisotropic intracellular organization or cell growth patterns that results in the shaping of a cell.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-09-16T09:25:18Z					biological_process											owl:Class	
GO:0061246	biolink:NamedThing	establishment or maintenance of bipolar cell polarity regulating cell shape	Any cellular process that results in the specification, formation or maintenance of a bipolar intracellular organization or cell growth patterns that regulates the shaping of a cell.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-08-23T09:46:01Z					biological_process											owl:Class	
GO:0097447	biolink:NamedThing	dendritic tree	The entire complement of dendrites for a neuron, consisting of each primary dendrite and all its branches.	tmpzr1t_l9r_go_relaxed.owl					NIF_Subcellular:sao172297168			pr	2012-12-17T12:31:49Z					cellular_component											owl:Class	
GO:0005784	biolink:NamedThing	Sec61 translocon complex	A translocon complex that contains a core heterotrimer of conserved alpha, beta and gamma subunits, and may contain additional proteins (translocon-associated proteins or TRAPs); in budding yeast the core proteins are Sec61p, Sbh1p, and Sss1p. The Sec61 translocon complex functions in cotranslational and posttranslational translocation events.	tmpzr1t_l9r_go_relaxed.owl	Sec61p-Sbh1p-Sss1p complex	https://github.com/geneontology/go-ontology/issues/22000												cellular_component											owl:Class	
GO:0071256	biolink:NamedThing	translocon complex	A protein complex that constitutes a specific site of protein translocation across the endoplasmic reticulum, which involves the signal recognition particle receptor. The complex contains a core heterotrimer of alpha, beta and gamma subunits, and may contain additional proteins.	tmpzr1t_l9r_go_relaxed.owl	Sec complex-associated translocon complex							mah	2009-12-08T02:08:03Z			GO:0031206		cellular_component											owl:Class	
GO:0036076	biolink:NamedThing	ligamentous ossification	Ossification wherein bone tissue forms within ligamentous tissue.	tmpzr1t_l9r_go_relaxed.owl						Ligamentous ossification may occur via replacement ossification or metaplastic ossification or both in any one instance.		bf	2011-12-19T01:57:08Z					biological_process											owl:Class	
GO:0003175	biolink:NamedThing	tricuspid valve development	The progression of the tricuspid valve over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-10-08T11:18:12Z					biological_process											owl:Class	
GO:0030986	biolink:NamedThing	low molecular weight kininogen binding	Binding to a kininogen of low molecular mass.	tmpzr1t_l9r_go_relaxed.owl	LK binding|LMW kininogen binding													molecular_function											owl:Class	
GO:0030984	biolink:NamedThing	kininogen binding	Binding to a kininogen, a kinin precursor.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0043042	biolink:NamedThing	amino acid adenylylation by nonribosomal peptide synthase	Activation of an amino acid for incorporation into a peptide by a nonribosomal process, catalyzed by subunits of nonribosomal peptide synthase. The amino acid is adenylated at its carboxylate group (ATP-dependent) then transferred to the thiol group of an enzyme-bound phosphopantetheine cofactor.	tmpzr1t_l9r_go_relaxed.owl	amino acid adenylation by NRPS|amino acid adenylation by nonribosomal peptide synthase													biological_process											owl:Class	
GO:0043041	biolink:NamedThing	amino acid activation for nonribosomal peptide biosynthetic process	Activation of an amino acid for incorporation into a peptide by a nonribosomal process.	tmpzr1t_l9r_go_relaxed.owl	nonribosomal amino acid activation													biological_process											owl:Class	
GO:0030645	biolink:NamedThing	glucose catabolic process to butyrate	The anaerobic chemical reactions and pathways resulting in the breakdown of glucose, with the production of acetic acid, butyric acid, carbon dioxide (CO2), and dihydrogen; effected by some saccharolytic species of Clostridium, e.g. C. butyricum.	tmpzr1t_l9r_go_relaxed.owl	butyrate fermentation|glucose fermentation to butyrate													biological_process											owl:Class	
GO:0006007	biolink:NamedThing	glucose catabolic process	The chemical reactions and pathways resulting in the breakdown of glucose, the aldohexose gluco-hexose.	tmpzr1t_l9r_go_relaxed.owl	glucose breakdown|glucose degradation|glucose catabolism													biological_process											owl:Class	
GO:0031871	biolink:NamedThing	proteinase activated receptor binding	Binding to a proteinase activated receptor.	tmpzr1t_l9r_go_relaxed.owl	proteinase activated receptor ligand													molecular_function											owl:Class	
GO:1905074	biolink:NamedThing	negative regulation of tight junction disassembly	Any process that stops, prevents or reduces the frequency, rate or extent of tight junction disassembly.	tmpzr1t_l9r_go_relaxed.owl	down regulation of occluding cell junction disassembly|inhibition of occluding junction disassembly|down-regulation of tight junction disassembly|inhibition of tight junction disassembly|inhibition of occluding cell junction disassembly|down-regulation of occluding cell junction disassembly|downregulation of occluding cell junction disassembly|negative regulation of occluding cell junction disassembly|downregulation of tight junction disassembly|down regulation of tight junction disassembly|downregulation of occluding junction disassembly							rl	2016-03-23T19:33:01Z					biological_process											owl:Class	
GO:0050939	biolink:NamedThing	regulation of early stripe melanocyte differentiation	Any process that modulates the frequency, rate or extent of early stripe melanocyte differentiation.	tmpzr1t_l9r_go_relaxed.owl	regulation of early stripe melanophore differentiation													biological_process											owl:Class	
GO:0003160	biolink:NamedThing	endocardium morphogenesis	The process in which the anatomical structure of the endocardium is generated and organized. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-10-01T01:37:26Z					biological_process											owl:Class	
GO:0043898	biolink:NamedThing	2,3-dihydroxybiphenyl 1,2-dioxygenase activity	Catalysis of the reaction: 2,3-dihydroxybiphenyl + O2 = 2-hydroxy-6-phenylhexa-2,4-dienoic acid.	tmpzr1t_l9r_go_relaxed.owl	2,3-dihydroxybiphenyl-1,2-dioxygenase activity|BphC													molecular_function											owl:Class	
GO:0014748	biolink:NamedThing	negative regulation of tonic skeletal muscle contraction	Any process that stops, prevents, or reduces the frequency, rate or extent of tonic skeletal muscle contraction.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0014746	biolink:NamedThing	regulation of tonic skeletal muscle contraction	Any process that modulates the frequency, rate or extent of tonic skeletal muscle contraction.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0031330	biolink:NamedThing	negative regulation of cellular catabolic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells.	tmpzr1t_l9r_go_relaxed.owl	down regulation of cellular catabolic process|negative regulation of cellular degradation|downregulation of cellular catabolic process|negative regulation of cellular breakdown|negative regulation of cellular catabolism|down-regulation of cellular catabolic process|inhibition of cellular catabolic process													biological_process											owl:Class	
GO:0010707	biolink:NamedThing	globoside biosynthetic process via lactosylceramide	The chemical reactions and pathways resulting in the formation of globosides that begins with the formation of lactosylceramides, Gal-beta-(1->4)-Glc-beta-(1->1') ceramides, any compound formed by the replacement of the glycosidic C1 hydroxyl group of lactose by a ceramide group.	tmpzr1t_l9r_go_relaxed.owl	globoside biosynthesis via lactosylceramide biosynthesis|lactosylceramide biosynthesis leading to globoside|biosynthesis of lactosylceramide precursor to globoside|lactosylceramide biosynthetic process leading to globoside													biological_process											owl:Class	
GO:0001576	biolink:NamedThing	globoside biosynthetic process	The chemical reactions and pathways resulting in the formation of a ceramide with a core structure of GalNAc-beta-(1->3)-Gal-alpha-(1->4)-Glc(I).	tmpzr1t_l9r_go_relaxed.owl	globoside formation|globoside biosynthesis|globoside anabolism|globoside synthesis													biological_process											owl:Class	
GO:1900853	biolink:NamedThing	negative regulation of terrequinone A biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of terrequinone A biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	downregulation of terrequinone A biosynthetic process|down-regulation of terrequinone A biosynthetic process|down regulation of terrequinone A biosynthetic process							di	2012-06-07T09:47:30Z					biological_process											owl:Class	
GO:1900852	biolink:NamedThing	regulation of terrequinone A biosynthetic process	Any process that modulates the frequency, rate or extent of terrequinone A biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of terrequinone A anabolism|regulation of terrequinone A formation|regulation of terrequinone A synthesis|regulation of terrequinone A biosynthesis							di	2012-06-07T09:47:09Z					biological_process											owl:Class	
GO:0010794	biolink:NamedThing	regulation of dolichol biosynthetic process	Any process that modulates the frequency, rate or extent of dolichol biosynthesis. Dolichol biosynthesis consists of the chemical reactions and pathways resulting in the formation of dolichols, any 2,3-dihydropolyprenol derived from four or more linked isoprene units.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0033485	biolink:NamedThing	cyanidin 3-O-glucoside biosynthetic process	The chemical reactions and pathways resulting in the formation of cyanidin 3-O-glucoside, a basic anthocyanin responsible for red to magenta coloration of flowers and fruits.	tmpzr1t_l9r_go_relaxed.owl	cyanidin 3-O-glucoside anabolism|cyanidin 3-O-glucoside formation|cyanidin 3-O-glucoside synthesis|cyanidin 3-O-glucoside biosynthesis				MetaCyc:PWY-5125									biological_process											owl:Class	
GO:0015972	biolink:NamedThing	guanosine pentaphosphate metabolic process	The chemical reactions and pathways involving guanine pentaphosphate (5'-pppGpp-3'), a derivative of guanine riboside with five phosphates.	tmpzr1t_l9r_go_relaxed.owl	guanosine pentaphosphate (5'-pppGpp-3') metabolism|guanosine pentaphosphate (5'-pppGpp-3') metabolic process|guanosine pentaphosphate metabolism													biological_process											owl:Class	
GO:0034035	biolink:NamedThing	purine ribonucleoside bisphosphate metabolic process	The chemical reactions and pathways involving a purine ribonucleoside bisphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar.	tmpzr1t_l9r_go_relaxed.owl	purine ribonucleoside bisphosphate metabolism													biological_process											owl:Class	
GO:0033113	biolink:NamedThing	cyanelle membrane	Either of the lipid bilayers that surround a cyanelle and form the cyanelle envelope.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0039520	biolink:NamedThing	induction by virus of host autophagy	Any process in which a virus activates or increases the frequency, rate or extent of autophagy in the host.	tmpzr1t_l9r_go_relaxed.owl	activation of host autophagy by virus|positive regulation by virus of host autophagy				VZ:846			bf	2011-06-22T04:24:47Z					biological_process											owl:Class	
GO:0075044	biolink:NamedThing	positive regulation by symbiont of host autophagy	Any process in which a symbiont organism increases the frequency, rate or extent of autophagy in the host cell. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	autophagy of host cells involved in interaction with symbiont|positive regulation by symbiont of host autophagotic process|autophagy of host cells during interaction with symbiont													biological_process											owl:Class	
GO:0140040	biolink:NamedThing	mitochondrial polycistronic RNA processing	The conversion of polycistronic RNA transcribed from a mitochondrial genome into mono- or bi-cistronic RNAs.	tmpzr1t_l9r_go_relaxed.owl								pg	2017-06-16T07:18:38Z					biological_process											owl:Class	
GO:0031426	biolink:NamedThing	polycistronic mRNA processing	The conversion of a primary mRNA transcript containing more than one complete protein-coding region into individual mature mRNA molecules.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0110153	biolink:NamedThing	RNA NAD-cap (NMN-forming) hydrolase activity	Catalysis of the reaction: a 5'-end NAD(+)-phospho-ribonucleoside in mRNA + H2O = a 5'-end phospho-adenosine-phospho-ribonucleoside in mRNA + beta-nicotinamide D-ribonucleotide + 2 H(+).	tmpzr1t_l9r_go_relaxed.owl					RHEA:60876	This reaction specifically removes the nicotinamide adenine dinucleotide (NAD) cap from a subset of mRNAs by hydrolyzing the diphosphate linkage to produce nicotinamide mononucleotide (NMN) and 5' monophosphate mRNA.		kmv	2019-07-08T17:15:59Z					molecular_function											owl:Class	
GO:0097543	biolink:NamedThing	ciliary inversin compartment	Proximal part of the ciliary shaft to which the inversin protein (also called Inv) specifically localizes. The inversin compartment appears to have a different protein composition than the rest of the cilium, although there is no structure that separates it form the distal part of the cilium.	tmpzr1t_l9r_go_relaxed.owl	inversin compartment|flagellum inversin compartment|Inv compartment of the cilium|flagellar inversin compartment|cilial inversin compartment|cilium inversin compartment					Note that cilia and eukaryotic flagella are deemed to be equivalent.		pr	2013-12-12T11:14:36Z					cellular_component											owl:Class	
GO:0006031	biolink:NamedThing	chitin biosynthetic process	The chemical reactions and pathways resulting in the formation of chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues.	tmpzr1t_l9r_go_relaxed.owl	beta-1,4-linked N-acetylglucosamine biosynthesis|chitin formation|beta-1,4-linked N-acetylglucosamine biosynthetic process|chitin anabolism|chitin synthesis|chitin biosynthesis													biological_process											owl:Class	
GO:0006030	biolink:NamedThing	chitin metabolic process	The chemical reactions and pathways involving chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues.	tmpzr1t_l9r_go_relaxed.owl	beta-1,4-linked N-acetylglucosamine metabolism|beta-1,4-linked N-acetylglucosamine metabolic process|chitin metabolism													biological_process											owl:Class	
GO:0018393	biolink:NamedThing	internal peptidyl-lysine acetylation	The addition of an acetyl group to a non-terminal lysine residue in a protein.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0018394	biolink:NamedThing	peptidyl-lysine acetylation	The acetylation of peptidyl-lysine.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0047420	biolink:NamedThing	N-acyl-D-amino-acid deacylase activity	Catalysis of the reaction: H2O + N-acyl-D-amino acid = D-amino acid + an acid.	tmpzr1t_l9r_go_relaxed.owl	N-acyl-D-amino acid amidohydrolase activity|D-aminoacylase activity				EC:3.5.1.81|RHEA:18309|MetaCyc:3.5.1.81-RXN									molecular_function											owl:Class	
GO:1901321	biolink:NamedThing	positive regulation of heart induction	Any process that activates or increases the frequency, rate or extent of heart induction.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of heart induction|upregulation of heart induction|up regulation of heart induction|activation of heart induction							bf	2012-08-28T15:49:51Z					biological_process											owl:Class	
GO:0070302	biolink:NamedThing	regulation of stress-activated protein kinase signaling cascade	Any process that modulates the frequency, rate or extent of signaling via a stress-activated protein kinase signaling cascade.	tmpzr1t_l9r_go_relaxed.owl	regulation of stress-activated protein kinase signaling pathway|regulation of stress-activated protein kinase signalling pathway|regulation of SAPK signaling pathway													biological_process											owl:Class	
GO:1902531	biolink:NamedThing	regulation of intracellular signal transduction	Any process that modulates the frequency, rate or extent of intracellular signal transduction.	tmpzr1t_l9r_go_relaxed.owl	regulation of intracellular protein kinase cascade|regulation of signal transduction via intracellular signaling cascade|regulation of intracellular signaling cascade|regulation of intracellular signaling pathway|regulation of intracellular signaling chain|regulation of intracellular signal transduction pathway|regulation of signal transmission via intracellular cascade							bf	2013-12-02T11:32:52Z			GO:0010627		biological_process											owl:Class	
GO:0014727	biolink:NamedThing	positive regulation of extraocular skeletal muscle development	Any process that activates, maintains or increases the frequency, rate or extent of extraocular skeletal muscle development. Extraocular skeletal muscle development is the process whose specific outcome is the progression of the extraocular skeletal muscle over time, from its formation to the mature structure. The extraocular muscle is derived from cranial mesoderm and controls eye movements. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0048643	biolink:NamedThing	positive regulation of skeletal muscle tissue development	Any process that activates, maintains or increases the rate of skeletal muscle tissue development.	tmpzr1t_l9r_go_relaxed.owl	up regulation of skeletal muscle development|activation of skeletal muscle development|upregulation of skeletal muscle development|up-regulation of skeletal muscle development|stimulation of skeletal muscle development													biological_process											owl:Class	
GO:0008635	biolink:NamedThing	activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c	Any process that initiates the activity of the inactive enzyme cysteine-type endopeptidase in the context of an apoptotic process and is mediated by cytochrome c.	tmpzr1t_l9r_go_relaxed.owl	caspase activation via cytochrome c|activation of caspase activity by cytochrome c													biological_process											owl:Class	
GO:0006919	biolink:NamedThing	activation of cysteine-type endopeptidase activity involved in apoptotic process	Any process that initiates the activity of the inactive enzyme cysteine-type endopeptidase in the context of an apoptotic process.	tmpzr1t_l9r_go_relaxed.owl	activation of caspase activity|caspase activation|activation of metacaspase activity					This term should be used when the annotation refers to a process that occurs in a context of apoptotic cell death. To annotate gene products involved in activation of cysteine-type endopeptidases in other cellular process (e.g., cell cycle arrest) that do not necessarily develop into an apoptotic process, please use the more general parent term GO:0097202. Examples of 'activation of cysteine-type endopeptidase activity involved in apoptotic process' are cytochrome c and Apaf1. When cytochrome c is released from mitochondria and forms a complex with Apaf1, they form a scaffolding platform in which the pro-caspase 9 is bound (the 'apoptosome'). The caspase is then cleaved and activated. Cytochrome c and Apaf1 are therefore involved in the conversion of the zymogen procaspase 9 to the active form of the caspase.								biological_process											owl:Class	
GO:0015724	biolink:NamedThing	formate transport	The directed movement of formate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0120313	biolink:NamedThing	regulation of oocyte karyosome formation	Any process that modulates the frequency, rate or extent of oocyte karyosome formation, the chromosome organization process in which meiotic chromosomes in the oocyte nucleus cluster together to form a compact spherical structure called the karyosome.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/21298						krc	2021-04-19T21:34:15Z					biological_process											owl:Class	
GO:1905656	biolink:NamedThing	positive regulation of artery smooth muscle contraction	Any process that activates or increases the frequency, rate or extent of artery smooth muscle contraction.	tmpzr1t_l9r_go_relaxed.owl	activation of artery smooth muscle contraction|up regulation of artery smooth muscle contraction|upregulation of artery smooth muscle contraction|up-regulation of artery smooth muscle contraction							rph	2016-11-09T12:35:01Z					biological_process											owl:Class	
GO:0062030	biolink:NamedThing	negative regulation of stress granule assembly	Any process that stops or decreases the rate, frequency or extent of stress-granule assembly, the aggregation, arrangement and bonding together of proteins and RNA molecules to form a stress granule.	tmpzr1t_l9r_go_relaxed.owl								dph	2018-04-16T19:19:32Z					biological_process											owl:Class	
GO:0062028	biolink:NamedThing	regulation of stress granule assembly	Any process that modulates the rate, frequency or extent of stress granule assembly, the aggregation, arrangement and bonding together of proteins and RNA molecules to form a stress granule.	tmpzr1t_l9r_go_relaxed.owl								dph	2018-04-16T19:12:41Z					biological_process											owl:Class	
GO:0009831	biolink:NamedThing	plant-type cell wall modification involved in multidimensional cell growth	The series of events that occur during cell growth that result in chemical or structural changes to existing cell walls of the type composed chiefly of cellulose and pectin. An example of this is found in Arabidopsis thaliana.	tmpzr1t_l9r_go_relaxed.owl	cellulose and pectin-containing cell wall modification during multidimensional cell growth|cell wall modification during cell expansion													biological_process											owl:Class	
GO:0009827	biolink:NamedThing	plant-type cell wall modification	The series of events leading to chemical and structural alterations of an existing cellulose and pectin-containing cell wall that can result in loosening, increased extensibility or disassembly. An example of this is found in Arabidopsis thaliana.	tmpzr1t_l9r_go_relaxed.owl	cellulose and pectin-containing cell wall modification													biological_process											owl:Class	
GO:0050869	biolink:NamedThing	negative regulation of B cell activation	Any process that stops, prevents, or reduces the frequency, rate or extent of B cell activation.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of B-cell activation|downregulation of B cell activation|down regulation of B cell activation|negative regulation of B lymphocyte activation|down-regulation of B cell activation|inhibition of B cell activation|negative regulation of B-lymphocyte activation													biological_process											owl:Class	
GO:0098737	biolink:NamedThing	protein insertion into plasma membrane	The process that results in the incorporation of a protein into a plasma membrane.  Incorporation in this context means having some part or covalently attached group that is inserted into the the hydrophobic region of one or both bilayers.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0051205	biolink:NamedThing	protein insertion into membrane	The process that results in the incorporation of a protein into a biological membrane.  Incorporation in this context means having some part or covalently attached group that is inserted into the the hydrophobic region of one or both bilayers.	tmpzr1t_l9r_go_relaxed.owl	protein-membrane insertion|integral membrane protein positioning|integral membrane protein localization|membrane protein positioning|membrane protein localization													biological_process											owl:Class	
GO:0003923	biolink:NamedThing	GPI-anchor transamidase activity	Catalysis of the formation of the linkage between a protein and a glycosylphosphatidylinositol anchor. The reaction probably occurs by subjecting a peptide bond to nucleophilic attack by the amino group of ethanolamine-GPI, transferring the protein from a signal peptide to the GPI anchor.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-162836									molecular_function											owl:Class	
GO:0004197	biolink:NamedThing	cysteine-type endopeptidase activity	Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile.	tmpzr1t_l9r_go_relaxed.owl	caspase activity|lysosomal cysteine-type endopeptidase|thiol endopeptidase activity|metacaspase activity				Reactome:R-HSA-1236948|Reactome:R-HSA-9013895|Reactome:R-HSA-201640|Reactome:R-HSA-350158|Reactome:R-HSA-202939|Reactome:R-HSA-351871|Reactome:R-HSA-351849|Reactome:R-HSA-211651|Reactome:R-HSA-352268|Reactome:R-HSA-2130336|Reactome:R-HSA-5357828|Reactome:R-HSA-350651|Reactome:R-HSA-9697750|Reactome:R-HSA-9694377|Reactome:R-HSA-9684340|Reactome:R-HSA-211186|Reactome:R-HSA-9694551|Reactome:R-HSA-201636|Reactome:R-HSA-202967|Reactome:R-HSA-9603534|Reactome:R-HSA-2130349|Reactome:R-HSA-9694625|Reactome:R-HSA-201628|Reactome:R-HSA-9694441|Reactome:R-HSA-5682377|Reactome:R-HSA-9012556|Reactome:R-HSA-5660663|Reactome:R-HSA-9694601|Reactome:R-HSA-351877|Reactome:R-HSA-351913|Reactome:R-HSA-264871|Reactome:R-HSA-9684273|Reactome:R-HSA-1678920|Reactome:R-HSA-418846|Reactome:R-HSA-1678981|Reactome:R-HSA-202969|Reactome:R-HSA-9647999|Reactome:R-HSA-418845|Reactome:R-HSA-201639|Reactome:R-HSA-139952|Reactome:R-HSA-9694732|Reactome:R-HSA-9684336|Reactome:R-HSA-351894|Reactome:R-HSA-201637|Reactome:R-HSA-202966|Reactome:R-HSA-202947|Reactome:R-HSA-201629|Reactome:R-HSA-351901|Reactome:R-HSA-201630|Reactome:R-HSA-202917|Reactome:R-HSA-351936|Reactome:R-HSA-2130706|Reactome:R-HSA-9684351|Reactome:R-HSA-2028697|Reactome:R-HSA-350319|Reactome:R-HSA-418852|Reactome:R-HSA-9684321|Reactome:R-HSA-448703|Reactome:R-HSA-9686930|Reactome:R-HSA-202960|Reactome:R-HSA-201634|Reactome:R-HSA-212552|Reactome:R-HSA-139898|Reactome:R-HSA-201608|Reactome:R-HSA-2562564|Reactome:R-HSA-9693929|Reactome:R-HSA-264865|Reactome:R-HSA-114252|Reactome:R-HSA-351876|Reactome:R-HSA-2028692|EC:3.4.22.-|Reactome:R-HSA-201622|Reactome:R-HSA-6814387|Reactome:R-HSA-201603|Reactome:R-HSA-350318|Reactome:R-HSA-201631|Reactome:R-HSA-9684352|Reactome:R-HSA-2130504|Reactome:R-HSA-211190|Reactome:R-HSA-114261|Reactome:R-HSA-933532|Reactome:R-HSA-114259|Reactome:R-HSA-201611|Reactome:R-HSA-3465448|Reactome:R-HSA-5634228|Reactome:R-HSA-9684309|Reactome:R-HSA-201595|Reactome:R-HSA-5681987|Reactome:R-HSA-9694338									molecular_function											owl:Class	
GO:0010916	biolink:NamedThing	negative regulation of very-low-density lipoprotein particle clearance	Any process that decreases the rate, frequency or extent of very-low-density lipoprotein particle clearance. Very-low-density lipoprotein particle clearance is the process in which a very-low-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of VLDL clearance|negative regulation of VLDL particle clearance													biological_process											owl:Class	
GO:0042817	biolink:NamedThing	pyridoxal metabolic process	The chemical reactions and pathways involving 3-hydroxy-5-(hydroxymethyl)-2-methyl-4-pyridinecarboxaldehyde, one of the vitamin B6 compounds. Pyridoxal, pyridoxamine and pyridoxine are collectively known as vitamin B6, and are efficiently converted to the biologically active form of vitamin B6, pyridoxal phosphate.	tmpzr1t_l9r_go_relaxed.owl	pyridoxal metabolism													biological_process											owl:Class	
GO:1900194	biolink:NamedThing	negative regulation of oocyte maturation	Any process that stops, prevents or reduces the frequency, rate or extent of oocyte maturation.	tmpzr1t_l9r_go_relaxed.owl	inhibition of oocyte maturation|down regulation of oocyte maturation|downregulation of oocyte maturation|down-regulation of oocyte maturation							kmv	2012-03-19T09:41:27Z					biological_process											owl:Class	
GO:1905455	biolink:NamedThing	positive regulation of myeloid progenitor cell differentiation	Any process that activates or increases the frequency, rate or extent of myeloid progenitor cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	up regulation of myeloid progenitor cell differentiation|up-regulation of myeloid progenitor cell differentiation|activation of myeloid progenitor cell differentiation|upregulation of myeloid progenitor cell differentiation							rz	2016-09-16T12:32:33Z					biological_process											owl:Class	
GO:1905453	biolink:NamedThing	regulation of myeloid progenitor cell differentiation	Any process that modulates the frequency, rate or extent of myeloid progenitor cell differentiation.	tmpzr1t_l9r_go_relaxed.owl								rz	2016-09-16T12:32:18Z					biological_process											owl:Class	
GO:1901066	biolink:NamedThing	syringal lignin biosynthetic process	The chemical reactions and pathways resulting in the formation of syringal lignin.	tmpzr1t_l9r_go_relaxed.owl	syringal lignin formation|syringal lignin anabolism|syringal lignin synthesis|syringal lignin biosynthesis|S-lignin biosynthetic process							tt	2012-06-29T03:48:41Z					biological_process											owl:Class	
GO:1901064	biolink:NamedThing	syringal lignin metabolic process	The chemical reactions and pathways involving syringal lignin.	tmpzr1t_l9r_go_relaxed.owl	S-lignin metabolic process|syringal lignin metabolism							tt	2012-06-29T03:48:11Z					biological_process											owl:Class	
GO:0007083	biolink:NamedThing	mitotic chromosome decondensation	The cell cycle process in which chromosome structure is altered from the condensed form taken on during mitosis to the relaxed disperse form held in resting cells.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0051898	biolink:NamedThing	negative regulation of protein kinase B signaling	Any process that stops, prevents, or reduces the frequency, rate or extent of protein kinase B signaling, a series of reactions mediated by the intracellular serine/threonine kinase protein kinase B.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of PKB signaling cascade|inhibition of protein kinase B signaling cascade|down-regulation of protein kinase B signaling cascade|negative regulation of PKB signalling cascade|down regulation of protein kinase B signaling cascade|negative regulation of AKT signaling cascade|negative regulation of AKT signalling cascade|downregulation of protein kinase B signaling cascade|negative regulation of protein kinase B signaling cascade|negative regulation of protein kinase B signalling cascade													biological_process											owl:Class	
GO:0072727	biolink:NamedThing	cellular response to CCCP	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a CCCP stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to carbonyl cyanide m-chlorophenyl hydrazone							mah	2012-05-31T11:16:43Z					biological_process											owl:Class	
GO:0098522	biolink:NamedThing	neuromuscular junction of skeletal muscle fiber	A neuromuscular junction in which the target muscle cell is a skeletal muscle fiber.	tmpzr1t_l9r_go_relaxed.owl						In vertebrates, the term 'neuromuscular junction' is limited to synapses targeting skeletal muscle fibers - all of which are  cholinergic and excitatory.  Both inhibitory and excitatory neuromuscular junctions exist in invertebrates, utilizing a range of neurotransmitters including glutamate, GABA and 5-HT.		dos	2013-10-14T12:04:32Z					cellular_component											owl:Class	
GO:0098981	biolink:NamedThing	cholinergic synapse	A synapse that uses acetylcholine as a neurotransmitter.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0150159	biolink:NamedThing	negative regulation of interleukin-34 production	Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-34 production.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of interleukin-34 biosynthetic process							bc	2020-01-06T16:31:12Z			GO:0150162		biological_process											owl:Class	
GO:0150157	biolink:NamedThing	regulation of interleukin-34 production	Any process that modulates the frequency, rate or extent of interleukin-34 production.	tmpzr1t_l9r_go_relaxed.owl	interleukin-34 biosynthetic process|regulation of interleukin-34 biosynthetic process							bc	2020-01-06T16:30:44Z			GO:0150156|GO:0150160		biological_process											owl:Class	
GO:1903934	biolink:NamedThing	positive regulation of DNA primase activity	Any process that activates or increases the frequency, rate or extent of DNA primase activity.	tmpzr1t_l9r_go_relaxed.owl	activation of DNA primase activity|up-regulation of DNA primase activity|upregulation of DNA primase activity|up regulation of DNA primase activity							mah	2015-02-12T14:28:45Z					biological_process											owl:Class	
GO:0051347	biolink:NamedThing	positive regulation of transferase activity	Any process that activates or increases the frequency, rate or extent of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from a donor compound to an acceptor.	tmpzr1t_l9r_go_relaxed.owl	stimulation of transferase activity|activation of transferase activity|up regulation of transferase activity|upregulation of transferase activity|transferase activator|up-regulation of transferase activity					This term is useful for grouping, but is too general for manual annotation. Please use a child term instead.								biological_process											owl:Class	
GO:0099520	biolink:NamedThing	ion antiporter activity involved in regulation of presynaptic membrane potential	Any ion antiporter activity, occurring in the presynaptic membrane, that is involved in regulation of presynaptic membrane potential.	tmpzr1t_l9r_go_relaxed.owl	ion antiporter activity involved in regulation of pre-synaptic membrane potential													molecular_function											owl:Class	
GO:0015297	biolink:NamedThing	antiporter activity	Enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported in opposite directions in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy. The reaction is: solute A(out) + solute B(in) = solute A(in) + solute B(out).	tmpzr1t_l9r_go_relaxed.owl	countertransporter activity|exchanger|solute:solute antiporter activity|porter|solute:solute exchange|ion antiporter activity|antiport|exchange transporter activity				Reactome:R-HSA-2731002|Reactome:R-HSA-2730692|Reactome:R-HSA-2730959							GO:0099516|GO:0015300		molecular_function											owl:Class	
GO:0101003	biolink:NamedThing	ficolin-1-rich granule membrane	The lipid bilayer surrounding a ficolin-1-rich granule.	tmpzr1t_l9r_go_relaxed.owl								mec						cellular_component											owl:Class	
GO:1900806	biolink:NamedThing	ergot alkaloid catabolic process	The chemical reactions and pathways resulting in the breakdown of ergot alkaloid.	tmpzr1t_l9r_go_relaxed.owl	ergot alkaloids degradation|ergot alkaloid breakdown|ergot alkaloid degradation|ergot alkaloids breakdown|ergot alkaloids catabolism|ergot alkaloid catabolism|ergot alkaloids catabolic process							di	2012-06-04T09:57:39Z					biological_process											owl:Class	
GO:0016143	biolink:NamedThing	S-glycoside metabolic process	The chemical reactions and pathways involving S-glycosides, any compound in which a glycosyl group has been substituted into a thiol group.	tmpzr1t_l9r_go_relaxed.owl	thioglycoside metabolic process|thioglycoside metabolism|S-glycoside metabolism													biological_process											owl:Class	
GO:0021740	biolink:NamedThing	principal sensory nucleus of trigeminal nerve development	The process whose specific outcome is the progression of the pontine nucleus over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl	pontine nucleus development					Note that this term was placed as a child of 'brain development' because the nucleus spans multiple brain regions.								biological_process											owl:Class	
GO:0021730	biolink:NamedThing	trigeminal sensory nucleus development	The process whose specific outcome is the progression of the trigeminal sensory nucleus over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl						Note that this term was placed as a child of 'brain development' because the nucleus spans multiple brain regions from midbrain to spinal cord.								biological_process											owl:Class	
GO:0042746	biolink:NamedThing	circadian sleep/wake cycle, wakefulness	The part of the circadian sleep/wake cycle where the organism is not asleep.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0022410	biolink:NamedThing	circadian sleep/wake cycle process	A behavioral process involved in the cycle from wakefulness through an orderly succession of sleep states and stages that occurs on an approximately 24 hour rhythm.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0047419	biolink:NamedThing	N-acetylgalactosamine-6-phosphate deacetylase activity	Catalysis of the reaction: H2O + N-acetyl-D-galactosamine 6-phosphate = acetate + D-galactosamine 6-phosphate.	tmpzr1t_l9r_go_relaxed.owl					RHEA:18149|EC:3.5.1.25|MetaCyc:3.5.1.80-RXN									molecular_function											owl:Class	
GO:0046083	biolink:NamedThing	adenine metabolic process	The chemical reactions and pathways involving adenine, 6-aminopurine, one of the five main bases found in nucleic acids and a component of numerous important derivatives of its corresponding ribonucleoside, adenosine.	tmpzr1t_l9r_go_relaxed.owl	adenine metabolism													biological_process											owl:Class	
GO:0045926	biolink:NamedThing	negative regulation of growth	Any process that stops, prevents or reduces the rate or extent of growth, the increase in size or mass of all or part of an organism.	tmpzr1t_l9r_go_relaxed.owl	inhibition of growth|downregulation of growth|down-regulation of growth|down regulation of growth													biological_process											owl:Class	
GO:0031000	biolink:NamedThing	response to caffeine	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a caffeine stimulus. Caffeine is an alkaloid found in numerous plant species, where it acts as a natural pesticide that paralyzes and kills certain insects feeding upon them.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0006783	biolink:NamedThing	heme biosynthetic process	The chemical reactions and pathways resulting in the formation of heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring, from less complex precursors.	tmpzr1t_l9r_go_relaxed.owl	heme anabolism|heme formation|heme synthesis|haem biosynthesis|heme biosynthesis|haem biosynthetic process				MetaCyc:HEMESYN2-PWY									biological_process											owl:Class	
GO:0102451	biolink:NamedThing	kaempferide 3-O-methyltransferase activity	Catalysis of the reaction: kaempferide + S-adenosyl-L-methionine  <=> 3,4'-dimethylkaempferol + S-adenosyl-L-homocysteine.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-13937									molecular_function											owl:Class	
GO:1900883	biolink:NamedThing	17-methylnonadec-1-ene biosynthetic process	The chemical reactions and pathways resulting in the formation of 17-methylnonadec-1-ene.	tmpzr1t_l9r_go_relaxed.owl	17-methylnonadec-1-ene anabolism|17-methylnonadec-1-ene formation|17-methylnonadec-1-ene biosynthesis|17-methylnonadec-1-ene synthesis							tt	2012-06-13T02:35:59Z					biological_process											owl:Class	
GO:1900882	biolink:NamedThing	17-methylnonadec-1-ene metabolic process	The chemical reactions and pathways involving 17-methylnonadec-1-ene.	tmpzr1t_l9r_go_relaxed.owl	17-methylnonadec-1-ene metabolism							tt	2012-06-13T02:35:37Z					biological_process											owl:Class	
GO:0044838	biolink:NamedThing	cell quiescence	A specialized resting state that cells enter in response to cues from the cell's environment. Quiescence is characterized by the absence of cell growth and division, by a reprogramming of global gene expression, and by changes characteristic of the organism and specific cell type. Depending on external conditions, quiescence may persist until cell death or cells may resume cell growth and division. In some cell types or under certain conditions, cellular metabolism may proceed.	tmpzr1t_l9r_go_relaxed.owl	G0 phase|cellular quiescence|cell cycle quiescence|quiescence					Note that terminally differentiated cells in higher eukaryotes are typically quiescent but metabolically active. Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during). Also, note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).		jl	2014-02-26T16:15:51Z					biological_process											owl:Class	
GO:0031864	biolink:NamedThing	EP1 subtype prostaglandin E2 receptor binding	Binding to an EP1 subtype prostaglandin E2 receptor.	tmpzr1t_l9r_go_relaxed.owl	EP1 subtype prostaglandin E2 receptor ligand|prostanoid EP1 receptor binding													molecular_function											owl:Class	
GO:0033719	biolink:NamedThing	2-oxo-acid reductase activity	Catalysis of the reaction: a (2R)-hydroxy-carboxylate + acceptor = a 2-oxo-carboxylate + reduced acceptor.	tmpzr1t_l9r_go_relaxed.owl	2-oxoacid reductase activity|(2R)-hydroxycarboxylate-viologen-oxidoreductase activity|(2R)-hydroxy-carboxylate:acceptor oxidoreductase activity|HVOR				RHEA:23664|MetaCyc:1.1.99.30-RXN|EC:1.1.99.30									molecular_function											owl:Class	
GO:1990361	biolink:NamedThing	PKM2 pyruvate kinase complex	A protein complex capable of pyruvate kinase activity. PKM2 only exists as homotetramer when bound to beta-d-fructofuranose 1,6-bisphosphate (CHEBI:28013).	tmpzr1t_l9r_go_relaxed.owl	PKM2 homotetramer					An example of this is PKM2 in human (P14618) in PMID:24606918 (inferred from direct assay).		bhm	2014-04-17T14:16:24Z					cellular_component											owl:Class	
GO:1902912	biolink:NamedThing	pyruvate kinase complex	A protein complex which is capable of pyruvate kinase activity.	tmpzr1t_l9r_go_relaxed.owl						An example of this is PKM2 in human (P14618) in PMID:24606918 (inferred from direct assay).		bhm	2014-04-17T14:11:41Z					cellular_component											owl:Class	
GO:0010767	biolink:NamedThing	regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage	Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a UV damage stimulus.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0006974	biolink:NamedThing	cellular response to DNA damage stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism.	tmpzr1t_l9r_go_relaxed.owl	cellular DNA damage response|response to genotoxic stress|DNA damage response|response to DNA damage stimulus											GO:0034984		biological_process											owl:Class	
GO:0034213	biolink:NamedThing	quinolinate catabolic process	The chemical reactions and pathways resulting in the breakdown of quinolinate, the anion of quinolinic acid, also known as 2,3-pyridinedicarboxylic acid.	tmpzr1t_l9r_go_relaxed.owl	quinolinate degradation|quinolinate catabolism|quinolinate breakdown													biological_process											owl:Class	
GO:0046874	biolink:NamedThing	quinolinate metabolic process	The chemical reactions and pathways involving quinolinate, the anion of quinolinic acid, also known as 2,3-pyridinedicarboxylic acid.	tmpzr1t_l9r_go_relaxed.owl	quinolinate metabolism													biological_process											owl:Class	
GO:1900549	biolink:NamedThing	N',N'',N'''-triacetylfusarinine C metabolic process	The chemical reactions and pathways involving N',N'',N'''-triacetylfusarinine C.	tmpzr1t_l9r_go_relaxed.owl	N',N'',N'''-triacetylfusarinine C metabolism							di	2012-05-15T12:59:06Z					biological_process											owl:Class	
GO:0032950	biolink:NamedThing	regulation of beta-glucan metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving beta-glucans.	tmpzr1t_l9r_go_relaxed.owl	regulation of beta-glucan metabolism													biological_process											owl:Class	
GO:0103090	biolink:NamedThing	methylthiohexylmalate dehydrogenase activity	Catalysis of the reaction: 3-(6'-methylthio)hexylmalate <=> H+ + 2-oxo-9-methylthiononanoate + carbon dioxide.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXNQT-4174									molecular_function											owl:Class	
GO:0098581	biolink:NamedThing	detection of external biotic stimulus	The series of events in which an external biotic stimulus is detected and converted into a molecular signal.  An external biotic stimulus is defined as one caused or produced by a living organism other than the one being stimulated.	tmpzr1t_l9r_go_relaxed.owl	detection of exogenous biotic stimulus							dos	2014-01-22T14:20:16Z					biological_process											owl:Class	
GO:1902229	biolink:NamedThing	regulation of intrinsic apoptotic signaling pathway in response to DNA damage	Any process that modulates the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to DNA damage.	tmpzr1t_l9r_go_relaxed.owl	regulation of DNA damage response, signal transduction resulting in induction of apoptosis							rl	2013-06-14T09:39:52Z					biological_process											owl:Class	
GO:1902817	biolink:NamedThing	negative regulation of protein localization to microtubule	Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to microtubule.	tmpzr1t_l9r_go_relaxed.owl	inhibition of protein localization to microtubule|down-regulation of protein localization to microtubule|inhibition of protein localisation to microtubule|negative regulation of protein localisation to microtubule|down regulation of protein localisation to microtubule|downregulation of protein localization to microtubule|down regulation of protein localization to microtubule|downregulation of protein localisation to microtubule|down-regulation of protein localisation to microtubule							tb	2014-03-27T22:07:18Z					biological_process											owl:Class	
GO:1902816	biolink:NamedThing	regulation of protein localization to microtubule	Any process that modulates the frequency, rate or extent of protein localization to microtubule.	tmpzr1t_l9r_go_relaxed.owl	regulation of protein localisation to microtubule							tb	2014-03-27T22:07:12Z					biological_process											owl:Class	
GO:1902778	biolink:NamedThing	response to alkane	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alkane stimulus.	tmpzr1t_l9r_go_relaxed.owl	process resulting in tolerance to alkane											GO:1990373		biological_process											owl:Class	
GO:0071380	biolink:NamedThing	cellular response to prostaglandin E stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin E stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-12-11T03:34:43Z					biological_process											owl:Class	
GO:0034695	biolink:NamedThing	response to prostaglandin E	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin E stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to prostaglandin E stimulus													biological_process											owl:Class	
GO:0017116	biolink:NamedThing	single-stranded DNA helicase activity	Catalysis of the reaction: ATP + H2O = ADP + phosphate, in the presence of single-stranded DNA; drives the unwinding of a DNA helix.	tmpzr1t_l9r_go_relaxed.owl	single-stranded DNA-dependent ATP-dependent DNA helicase activity|ssDNA-dependent ATPase activity|ssDNA-dependent ATP-dependent DNA helicase activity|single-stranded DNA-dependent ATPase activity											GO:0043142		molecular_function											owl:Class	
GO:0003678	biolink:NamedThing	DNA helicase activity	Unwinding of a DNA helix, driven by ATP hydrolysis.	tmpzr1t_l9r_go_relaxed.owl	ATP-dependent DNA helicase activity				Reactome:R-HSA-5693589|EC:3.6.4.12							GO:0003679|GO:0004003		molecular_function											owl:Class	
GO:0019983	biolink:NamedThing	interleukin-9 binding	Binding to interleukin-9.	tmpzr1t_l9r_go_relaxed.owl	IL-9 binding													molecular_function											owl:Class	
GO:0018097	biolink:NamedThing	protein-chromophore linkage via peptidyl-S-4-hydroxycinnamyl-L-cysteine	The synthesis of the chromophore S-4-hydroxycinnamyl-L-cysteine.	tmpzr1t_l9r_go_relaxed.owl	protein amino acid cinnamylation				RESID:AA0207									biological_process											owl:Class	
GO:0048456	biolink:NamedThing	stamen structural organization	The process that contributes to the act of creating the structural organization of the stamen. This process pertains to the physical shaping of a rudimentary structure.	tmpzr1t_l9r_go_relaxed.owl	stamen structural organisation											GO:0048428		biological_process											owl:Class	
GO:0048450	biolink:NamedThing	floral organ structural organization	The process that contributes to the act of creating the structural organization of floral organs. This process pertains to the physical shaping of a rudimentary structure.	tmpzr1t_l9r_go_relaxed.owl	floral organ structural organisation											GO:0048435		biological_process											owl:Class	
GO:0046109	biolink:NamedThing	uridine biosynthetic process	The chemical reactions and pathways resulting in the formation of uridine, uracil riboside, a ribonucleoside very widely distributed but occurring almost entirely as phosphoric esters in ribonucleotides and ribonucleic acids.	tmpzr1t_l9r_go_relaxed.owl	uridine biosynthesis|uridine formation|uridine anabolism|uridine synthesis													biological_process											owl:Class	
GO:0046132	biolink:NamedThing	pyrimidine ribonucleoside biosynthetic process	The chemical reactions and pathways resulting in the formation of any ribonucleoside, a nucleoside in which a pyrimidine base is linked to a ribose (beta-D-ribofuranose) molecule.	tmpzr1t_l9r_go_relaxed.owl	pyrimidine ribonucleoside anabolism|pyrimidine ribonucleoside biosynthesis|pyrimidine ribonucleoside synthesis|pyrimidine ribonucleoside formation													biological_process											owl:Class	
GO:0044761	biolink:NamedThing	negative regulation by symbiont of host cholinergic synaptic transmission	Any process in which a symbiont organism negatively regulates cholinergic synaptic transmission, communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse via the neurotransmitter choline, in its host organism.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-12-06T15:43:53Z					biological_process											owl:Class	
GO:0044760	biolink:NamedThing	modulation by symbiont of host cholinergic synaptic transmission	Any process in which a symbiont organism modulates the frequency, rate or extent of cholinergic synaptic transmission, communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse via the neurotransmitter choline, in its host organism.	tmpzr1t_l9r_go_relaxed.owl	regulation by symbiont of host cholinergic synaptic transmission							jl	2012-12-06T15:39:46Z					biological_process											owl:Class	
GO:1904716	biolink:NamedThing	positive regulation of chaperone-mediated autophagy	Any process that activates or increases the frequency, rate or extent of chaperone-mediated autophagy.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of chaperone-mediated autophagy|positive regulation of CMA|up regulation of chaperone-mediated autophagy|upregulation of chaperone-mediated autophagy|upregulation of CMA|up regulation of CMA|activation of chaperone-mediated autophagy|activation of CMA|up-regulation of CMA							pad	2015-10-06T08:49:15Z					biological_process											owl:Class	
GO:1904714	biolink:NamedThing	regulation of chaperone-mediated autophagy	Any process that modulates the frequency, rate or extent of chaperone-mediated autophagy.	tmpzr1t_l9r_go_relaxed.owl	regulation of CMA							pad	2015-10-06T08:49:02Z					biological_process											owl:Class	
GO:1904330	biolink:NamedThing	positive regulation of myofibroblast contraction	Any process that activates or increases the frequency, rate or extent of myofibroblast contraction.	tmpzr1t_l9r_go_relaxed.owl	activation of MFB contraction|upregulation of MFB contraction|upregulation of myofibroblast contraction|up-regulation of MF contraction|up regulation of myofibroblast contraction|up regulation of MFB contraction|activation of MF contraction|positive regulation of MFB contraction|up regulation of MF contraction|upregulation of MF contraction|up-regulation of MFB contraction|positive regulation of MF contraction|up-regulation of myofibroblast contraction|activation of myofibroblast contraction							sl	2015-06-11T15:30:41Z					biological_process											owl:Class	
GO:1990191	biolink:NamedThing	cobalamin transport complex	Protein complex facilitating ATP-dependent cobalamin (vitamin B12) transport through inner cell membrane (periplasm to cytoplasm) in Gram-negative bacteria. In E. coli the system is composed of a periplasmic cobalamin-binding protein (BtuF), an integral membrane homodimer, BtuC, and a cytoplasmic ATP-binding homodimer BtuD.	tmpzr1t_l9r_go_relaxed.owl	vitamin B12-transporting BtuCDF complex|vitamin B12 transport complex|cobalamin-transporting BtuCDF complex|BtuCDF complex							bhm	2013-09-12T14:20:19Z					cellular_component											owl:Class	
GO:0000215	biolink:NamedThing	tRNA 2'-phosphotransferase activity	Catalysis of the reaction: 2'-phospho-[ligated tRNA] + NAD+ = mature tRNA + ADP ribose 1'',2''-phosphate + nicotinamide + H2O. This reaction is the transfer of the splice junction 2-phosphate from ligated tRNA to NAD+ to produce ADP-ribose 1'-2' cyclic phosphate.	tmpzr1t_l9r_go_relaxed.owl	Tpt1|Tpt1p|2'-phosphotransferase activity|yeast 2'-phosphotransferase activity|2'-phospho-[ligated tRNA]:NAD+ phosphotransferase activity|2'-phospho-tRNA:NAD+ phosphotransferase activity				MetaCyc:2.7.1.160-RXN|RHEA:23324|EC:2.7.1.160							GO:0008665		molecular_function											owl:Class	
GO:0021874	biolink:NamedThing	Wnt signaling pathway involved in forebrain neuroblast division	The series of molecular signals initiated by binding of Wnt protein to a receptor on the surface of the target cell that contributes to the self renewal of neuroblasts in the forebrain.	tmpzr1t_l9r_go_relaxed.owl	Wnt receptor signalling pathway in forebrain neuroblast division|Wnt receptor signaling pathway involved in forebrain neuroblast division|Wnt-activated signaling pathway involved in forebrain neuroblast division													biological_process											owl:Class	
GO:0045487	biolink:NamedThing	gibberellin catabolic process	The chemical reactions and pathways resulting in the breakdown of gibberellin. Gibberellins are a class of highly modified terpenes that function as plant growth regulators.	tmpzr1t_l9r_go_relaxed.owl	gibberellin catabolism|gibberellic acid catabolic process|gibberellic acid breakdown|gibberellic acid catabolism|gibberellic acid degradation													biological_process											owl:Class	
GO:0016103	biolink:NamedThing	diterpenoid catabolic process	The chemical reactions and pathways resulting in the breakdown of diterpenoid compounds, terpenoids with four isoprene units.	tmpzr1t_l9r_go_relaxed.owl	diterpenoid breakdown|diterpene catabolism|diterpene catabolic process|diterpenoid catabolism|diterpenoid degradation													biological_process											owl:Class	
GO:1903610	biolink:NamedThing	regulation of calcium-dependent ATPase activity	Any process that modulates the frequency, rate or extent of calcium-dependent ATPase activity.	tmpzr1t_l9r_go_relaxed.owl								sl	2014-11-18T00:42:49Z					biological_process											owl:Class	
GO:0036182	biolink:NamedThing	asperthecin metabolic process	The chemical reactions and pathways involving asperthecin, an anthraquinone pigment obtained from the mould Aspergillus nidulans.	tmpzr1t_l9r_go_relaxed.owl	asperthecin metabolism							bf	2012-04-16T11:35:24Z					biological_process											owl:Class	
GO:0019748	biolink:NamedThing	secondary metabolic process	The chemical reactions and pathways resulting in many of the chemical changes of compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon. In multicellular organisms secondary metabolism is generally carried out in specific cell types, and may be useful for the organism as a whole. In unicellular organisms, secondary metabolism is often used for the production of antibiotics or for the utilization and acquisition of unusual nutrients.	tmpzr1t_l9r_go_relaxed.owl	secondary metabolite metabolism|secondary metabolite metabolic process|secondary metabolism				Wikipedia:Secondary_metabolism									biological_process											owl:Class	
GO:1904059	biolink:NamedThing	regulation of locomotor rhythm	Any process that modulates the frequency, rate or extent of locomotor rhythm.	tmpzr1t_l9r_go_relaxed.owl	regulation of circadian locomotor activity rhythm							sl	2015-03-18T20:38:52Z					biological_process											owl:Class	
GO:0001554	biolink:NamedThing	luteolysis	The lysis or structural demise of the corpus luteum. During normal luteolysis, two closely related events occur. First, there is loss of the capacity to synthesize and secrete progesterone (functional luteolysis) followed by loss of the cells that comprise the corpus luteum (structural luteolysis). Preventing luteolysis is crucial to maintain pregnancy.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Luteolysis									biological_process											owl:Class	
GO:0006768	biolink:NamedThing	biotin metabolic process	The chemical reactions and pathways involving biotin, cis-tetrahydro-2-oxothieno(3,4-d)imidazoline-4-valeric acid; the (+) enantiomer is very widely distributed in cells and serves as a carrier in a number of enzymatic beta-carboxylation reactions.	tmpzr1t_l9r_go_relaxed.owl	vitamin H metabolic process|biotin metabolism|vitamin H metabolism|vitamin B7 metabolism|vitamin B7 metabolic process				Wikipedia:Biotin									biological_process											owl:Class	
GO:0010309	biolink:NamedThing	acireductone dioxygenase [iron(II)-requiring] activity	Catalysis of the reaction: 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + O(2) = 4-methylthio-2-oxobutanoate + formate + H(+).	tmpzr1t_l9r_go_relaxed.owl	E-2'|ARD'|aci-reductone dioxygenase|acireductone dioxygenase activity|1,2-dihydroxy-5-(methylthio)pent-1-en-3-one:oxygen oxidoreductase (formate-forming)|ARD1|acireductone dioxygenase (Fe2+-requiring) activity|1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase activity|2-hydroxy-3-keto-5-thiomethylpent-1-ene dioxygenase				KEGG_REACTION:R07364|EC:1.13.11.54|MetaCyc:R147-RXN|Reactome:R-HSA-1237119|RHEA:24504									molecular_function											owl:Class	
GO:0102455	biolink:NamedThing	anthocyanidin 3-O-glucoside 2''-O-glucosyltransferase activity	Catalysis of the reaction: UDP-alpha-D-glucose + an anthocyanidin-3-O-beta-D-glucoside = UDP + H+ + an anthocyanidin 3-O-sophoroside.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-13965|EC:2.4.1.297|RHEA:35419									molecular_function											owl:Class	
GO:0005347	biolink:NamedThing	ATP transmembrane transporter activity	Enables the transfer of ATP, adenosine triphosphate, from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl												GO:0005348		molecular_function											owl:Class	
GO:0000295	biolink:NamedThing	adenine nucleotide transmembrane transporter activity	Enables the transfer of adenine nucleotides (AMP, ADP, and ATP) from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-389652									molecular_function											owl:Class	
GO:0140049	biolink:NamedThing	regulation of endocardial cushion to mesenchymal transition	Any process that modulates the frequency, rate or extent of endocardial cushion to mesenchymal transition.	tmpzr1t_l9r_go_relaxed.owl								pg	2017-06-23T15:57:00Z					biological_process											owl:Class	
GO:0090373	biolink:NamedThing	negative regulation of glycerol transport	Any process that decreases the rate, frequency, or extent of the directed movement of glycerol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl								tb	2010-07-12T11:30:22Z					biological_process											owl:Class	
GO:0071718	biolink:NamedThing	sodium-independent icosanoid transport	The directed, sodium-independent, movement of icosanoids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Icosanoids are unsaturated C20 fatty acids and skeletally related compounds.	tmpzr1t_l9r_go_relaxed.owl	sodium-independent eicosanoid transport							mah	2010-03-10T03:05:13Z					biological_process											owl:Class	
GO:0022878	biolink:NamedThing	protein-N(PI)-phosphohistidine-sucrose phosphotransferase system transporter activity	Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + sucrose(out) = protein histidine + sucrose phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.	tmpzr1t_l9r_go_relaxed.owl	sucrose PTS transporter activity				MetaCyc:SUCROSEPHOSPHO-RXN|RHEA:49236									molecular_function											owl:Class	
GO:0008515	biolink:NamedThing	sucrose transmembrane transporter activity	Enables the transfer of sucrose from one side of a membrane to the other. Sucrose is the disaccharide O-beta-D-fructofuranosyl-(2->1)-alpha-D-glucopyranoside, a sweet-tasting, non-reducing sugar isolated industrially from sugar beet or sugar cane.	tmpzr1t_l9r_go_relaxed.owl	sucrose permease activity|sucrose permease (PTS) activity											GO:0019188		molecular_function											owl:Class	
GO:0008219	biolink:NamedThing	cell death	Any biological process that results in permanent cessation of all vital functions of a cell. A cell should be considered dead when any one of the following molecular or morphological criteria is met: (1) the cell has lost the integrity of its plasma membrane; (2) the cell, including its nucleus, has undergone complete fragmentation into discrete bodies (frequently referred to as apoptotic bodies). The cell corpse (or its fragments) may be engulfed by an adjacent cell in vivo, but engulfment of whole cells should not be considered a strict criteria to define cell death as, under some circumstances, live engulfed cells can be released from phagosomes (see PMID:18045538).	tmpzr1t_l9r_go_relaxed.owl	necrosis|accidental cell death					This term should not be used for direct annotation. The only exception should be when experimental data (e.g., staining with trypan blue or propidium iodide) show that cell death has occurred, but fail to provide details on death modality (accidental versus programmed). When information is provided on the cell death mechanism, annotations should be made to the appropriate descendant of 'cell death' (such as, but not limited to, GO:0097300 'programmed necrotic cell death' or GO:0006915 'apoptotic process'). Also, if experimental data suggest that a gene product influences cell death indirectly, rather than being involved in the death process directly, consider annotating to a 'regulation' term.								biological_process											owl:Class	
GO:1905777	biolink:NamedThing	regulation of exonuclease activity	Any process that modulates the frequency, rate or extent of exonuclease activity.	tmpzr1t_l9r_go_relaxed.owl	regulation of exonuclease IX activity							nc	2016-12-21T21:32:07Z					biological_process											owl:Class	
GO:2000321	biolink:NamedThing	positive regulation of T-helper 17 cell differentiation	Any process that activates or increases the frequency, rate or extent of T-helper 17 cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of T-helper 17 cell development							mah	2011-01-18T01:45:08Z					biological_process											owl:Class	
GO:0045624	biolink:NamedThing	positive regulation of T-helper cell differentiation	Any process that activates or increases the frequency, rate or extent of T-helper cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	upregulation of T-helper cell differentiation|stimulation of T-helper cell differentiation|positive regulation of T-helper cell development|up-regulation of T-helper cell differentiation|activation of T-helper cell differentiation|up regulation of T-helper cell differentiation					Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.								biological_process											owl:Class	
GO:0004053	biolink:NamedThing	arginase activity	Catalysis of the reaction: L-arginine + H2O = L-ornithine + urea.	tmpzr1t_l9r_go_relaxed.owl	L-arginase activity|arginine transamidinase activity|L-arginine amidinohydrolase activity|canavanase activity|arginine amidinase activity				Reactome:R-HSA-70569|EC:3.5.3.1|MetaCyc:ARGINASE-RXN|RHEA:20569|Reactome:R-HSA-452036									molecular_function											owl:Class	
GO:0005362	biolink:NamedThing	low-affinity glucose:sodium symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucose(out) + Na+(out) = glucose(in) + Na+(in). In low-affinity transport the transporter is able to bind the solute only if it is present at very high concentrations.	tmpzr1t_l9r_go_relaxed.owl	low-affinity glucose-sodium cotransporter activity				Reactome:R-HSA-429567									molecular_function											owl:Class	
GO:0005412	biolink:NamedThing	glucose:sodium symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucose(out) + Na+(out) = glucose(in) + Na+(in).	tmpzr1t_l9r_go_relaxed.owl	sodium/glucose symporter activity				Reactome:R-HSA-5656356|Reactome:R-HSA-5658163|Reactome:R-HSA-429613|Reactome:R-HSA-8932955|Reactome:R-HSA-189208									molecular_function											owl:Class	
GO:0099010	biolink:NamedThing	modification of postsynaptic structure	Any process that modifies the structure of a postsynapse.	tmpzr1t_l9r_go_relaxed.owl	synapse remodelling					This class does not cover assembly or disassembly of postsynapses, only the modification/remodelling of existing ones.								biological_process											owl:Class	
GO:0099563	biolink:NamedThing	modification of synaptic structure	Any process that modifies the structure/morphology of a synapse.	tmpzr1t_l9r_go_relaxed.owl	synapse remodelling					This class does not cover assembly or disassembly of synapses, only the modification/remodelling of existing ones.								biological_process											owl:Class	
GO:0099592	biolink:NamedThing	endocytosed synaptic vesicle processing via endosome	The process in which endocytosed synaptic vesicles fuse to the presynaptic endosome followed by sorting of synaptic vesicle components and budding of new synaptic vesicles.	tmpzr1t_l9r_go_relaxed.owl	synaptic vesicle processing via endosome involved in synaptic vesicle recycling													biological_process											owl:Class	
GO:0099532	biolink:NamedThing	synaptic vesicle endosomal processing	The process in which synaptic vesicles fuse to the presynaptic endosome followed by sorting of synaptic vesicle components and budding of new synaptic vesicles.	tmpzr1t_l9r_go_relaxed.owl	synaptic vesicle processing via endosome					This covers processing of synaptic vesicles trafficked to synapse as well as  of endocytosed vesicles as part of recycling.  It is there for not part of the synaptic vesicle cycle.								biological_process											owl:Class	
GO:0060853	biolink:NamedThing	Notch signaling pathway involved in arterial endothelial cell fate commitment	The series of molecular signals initiated by binding of an extracellular ligand to a Notch receptor on the surface of the target cell and contributing to the commitment of a cell to an arterial endothelial cell fate.	tmpzr1t_l9r_go_relaxed.owl	Notch signalling pathway involved in arterial endothelial cell fate commitment							dph	2009-08-12T11:54:49Z					biological_process											owl:Class	
GO:0007219	biolink:NamedThing	Notch signaling pathway	A series of molecular signals initiated by the binding of an extracellular ligand to the receptor Notch on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.	tmpzr1t_l9r_go_relaxed.owl	Notch signalling pathway|Notch receptor signalling pathway|Notch-receptor signalling pathway|Notch-receptor signaling pathway|N signalling pathway|Notch receptor signaling pathway|N signaling pathway				Wikipedia:Notch_signaling_pathway							GO:0030179		biological_process											owl:Class	
GO:1903435	biolink:NamedThing	positive regulation of constitutive secretory pathway	Any process that activates or increases the frequency, rate or extent of constitutive secretory pathway.	tmpzr1t_l9r_go_relaxed.owl	upregulation of constitutive secretory pathway|up-regulation of constitutive secretory pathway|up regulation of constitutive secretory pathway|activation of constitutive secretory pathway							als	2014-09-15T15:07:48Z					biological_process											owl:Class	
GO:0018427	biolink:NamedThing	copper incorporation into metallo-sulfur cluster	The incorporation of copper into a metallo-sulfur cluster.	tmpzr1t_l9r_go_relaxed.owl	copper incorporation into metallo-sulphur cluster													biological_process											owl:Class	
GO:0042559	biolink:NamedThing	pteridine-containing compound biosynthetic process	The chemical reactions and pathways resulting in the formation of any compound containing pteridine (pyrazino(2,3-dipyrimidine)), e.g. pteroic acid, xanthopterin and folic acid.	tmpzr1t_l9r_go_relaxed.owl	pteridine and derivative biosynthetic process|pteridine-containing compound synthesis|pteridine and derivative biosynthesis|pteridine-containing compound biosynthesis|pterin biosynthesis|pterin biosynthetic process|pteridine-containing compound anabolism|pteridine-containing compound formation													biological_process											owl:Class	
GO:0061225	biolink:NamedThing	mesonephric extraglomerular mesangial cell proliferation involved in mesonephros development	The multiplication or reproduction of extraglomerular glomerular mesangium cells in the mesonephros by cell division, resulting in the expansion of their population. Extraglomerular mesangial cells (also known as lacis cells, Goormaghtigh cells) are light-staining cells in the kidney found outside the glomerulus, near the vascular pole and macula densa.	tmpzr1t_l9r_go_relaxed.owl	mesonephric lacis cell proliferation|mesonephric Goormaghtigh proliferation							dph	2010-08-19T01:34:59Z					biological_process											owl:Class	
GO:0070972	biolink:NamedThing	protein localization to endoplasmic reticulum	A process in which a protein is transported to, or maintained in, a location within the endoplasmic reticulum.	tmpzr1t_l9r_go_relaxed.owl	protein localisation in endoplasmic reticulum|protein localization in ER|protein localization in endoplasmic reticulum							mah	2009-10-02T12:43:34Z					biological_process											owl:Class	
GO:0033365	biolink:NamedThing	protein localization to organelle	A process in which a protein is transported to, or maintained in, a location within an organelle.	tmpzr1t_l9r_go_relaxed.owl	protein localisation to organelle|protein localization in organelle													biological_process											owl:Class	
GO:0046691	biolink:NamedThing	intracellular canaliculus	An apical plasma membrane part that forms a narrow enfolded luminal membrane channel, lined with numerous microvilli, that appears to extend into the cytoplasm of the cell. A specialized network of intracellular canaliculi is a characteristic feature of parietal cells of the gastric mucosa in vertebrates.	tmpzr1t_l9r_go_relaxed.owl	canalicular membrane													cellular_component											owl:Class	
GO:1900358	biolink:NamedThing	negative regulation of nigerotriose transport	Any process that stops, prevents or reduces the frequency, rate or extent of nigerotriose transport.	tmpzr1t_l9r_go_relaxed.owl	downregulation of nigerotriose transport|down regulation of nigerotriose transport|inhibition of nigerotriose transport|down-regulation of nigerotriose transport							tt	2012-04-06T02:18:21Z					biological_process											owl:Class	
GO:1905787	biolink:NamedThing	regulation of detection of mechanical stimulus involved in sensory perception of touch	Any process that modulates the frequency, rate or extent of detection of mechanical stimulus involved in sensory perception of touch.	tmpzr1t_l9r_go_relaxed.owl	regulation of perception of touch, detection of mechanical stimulus|regulation of sensory detection of mechanical stimulus during perception of touch|regulation of perception of touch, sensory detection of mechanical stimulus|regulation of tactition, sensory detection of mechanical stimulus|regulation of perception of touch, sensory transduction of mechanical stimulus|regulation of sensory transduction of mechanical stimulus during perception of touch							hbye	2017-01-09T15:11:04Z					biological_process											owl:Class	
GO:0051931	biolink:NamedThing	regulation of sensory perception	Any process that modulates the frequency, rate or extent of sensory perception, the series of events required for an organism to receive a sensory stimulus, convert it to a molecular signal, and recognize and characterize the signal.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0001867	biolink:NamedThing	complement activation, lectin pathway	Any process involved in the activation of any of the steps of the lectin pathway of the complement cascade which allows for the direct killing of microbes and the regulation of other immune processes.	tmpzr1t_l9r_go_relaxed.owl	complement cascade, lectin pathway					Note that proteins such as mannose-binding lectin (MBL) and certain serum ficolins can activate the lectin complement pathway.								biological_process											owl:Class	
GO:0005343	biolink:NamedThing	organic acid:sodium symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: organic acid(out) + Na+(out) = organic acid(in) + Na+(in).	tmpzr1t_l9r_go_relaxed.owl	sodium/chloride-dependent organic acid cotransporter activity|sodium:dicarboxylate/tricarboxylate symporter activity				Reactome:R-HSA-8876312									molecular_function											owl:Class	
GO:1903011	biolink:NamedThing	negative regulation of bone development	Any process that stops, prevents or reduces the frequency, rate or extent of bone development.	tmpzr1t_l9r_go_relaxed.owl	downregulation of bone development|inhibition of bone development|down regulation of bone development|down-regulation of bone development							mr	2014-05-13T22:42:00Z					biological_process											owl:Class	
GO:1901263	biolink:NamedThing	positive regulation of sorocarp spore cell differentiation	Any process that activates or increases the frequency, rate or extent of sorocarp spore cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	up regulation of sorocarp spore cell differentiation|upregulation of sorocarp spore cell differentiation|up-regulation of sorocarp spore cell differentiation|activation of sorocarp spore cell differentiation							jl	2012-08-15T09:44:58Z					biological_process											owl:Class	
GO:1990590	biolink:NamedThing	ATF1-ATF4 transcription factor complex	Transcription factor complex consisting of ATF1 and ATF4 subunits that is capable of binding to cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3') of the GRP78 (HSPA5) promoter. Involved in the ER stress response pathway.	tmpzr1t_l9r_go_relaxed.owl						An example of this is ATF1in human (P18846) in PMID:12871976 (inferred from physical interaction).		bhm	2014-12-15T14:25:56Z					cellular_component											owl:Class	
GO:0035872	biolink:NamedThing	nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway	A series of molecular signals generated as a consequence of a nucleotide-binding domain, leucine rich repeat containing receptor (NLR) binding to one of its physiological ligands. NLRs are cytoplasmic receptors defined by their tripartite domain architecture that contains: a variable C-terminus, a middle nucleotide-binding domain, and a LRR domain that is variable in the repeats composition and number. The NLR signaling pathway begins with binding of a ligand to a NLR receptor and ends with regulation of a downstream cellular process.	tmpzr1t_l9r_go_relaxed.owl	NOD-like receptor signaling pathway|nucleotide-binding domain, leucine rich repeat containing receptor signal transduction pathway|NLR signaling pathway|nucleotide-binding domain leucine-rich repeat containing receptor signaling pathway|nucleotide-binding domain, leucine rich repeat containing receptor signalling pathway|nucleotide-binding domain, leucine rich repeat containing receptor signal transduction							bf	2011-05-26T03:30:36Z					biological_process											owl:Class	
GO:0044468	biolink:NamedThing	envenomation resulting in modulation of blood coagulation in other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the modulation of the frequency, rate or extent of blood coagulation in the bitten organism.	tmpzr1t_l9r_go_relaxed.owl	envenomation resulting in regulation of blood coagulation in other organism							jl	2012-01-19T01:24:10Z					biological_process											owl:Class	
GO:0043520	biolink:NamedThing	regulation of myosin II filament assembly	Any process that modulates the frequency, rate or extent of the formation of a bipolar filament composed of myosin II molecules.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1901735	biolink:NamedThing	(R)-mevalonic acid metabolic process	The chemical reactions and pathways involving (R)-mevalonic acid.	tmpzr1t_l9r_go_relaxed.owl	(R)-mevalonic acid metabolism|(R) mevalonate metabolism							yaf	2013-01-11T11:25:50Z					biological_process											owl:Class	
GO:1900241	biolink:NamedThing	positive regulation of phenotypic switching	Any process that activates or increases the frequency, rate or extent of phenotypic switching.	tmpzr1t_l9r_go_relaxed.owl	activation of phenotypic dimorphism|up regulation of phenotypic dimorphism|positive regulation of phenotypic dimorphism|activation of phenotypic switching|up-regulation of phenotypic dimorphism|up regulation of phenotypic switching|upregulation of phenotypic dimorphism|up-regulation of phenotypic switching|upregulation of phenotypic switching							di	2012-03-28T01:49:34Z					biological_process											owl:Class	
GO:0102734	biolink:NamedThing	brassinolide synthase activity	Catalysis of the reaction: H+ + castasterone + NADPH + O2 <=> brassinolide + NADP + H2O.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-720									molecular_function											owl:Class	
GO:2000130	biolink:NamedThing	positive regulation of octopamine signaling pathway	Any process that activates or increases the frequency, rate or extent of octopamine signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of octopamine signalling pathway							mah	2010-09-29T09:29:47Z					biological_process											owl:Class	
GO:2000127	biolink:NamedThing	positive regulation of octopamine or tyramine signaling pathway	Any process that activates or increases the frequency, rate or extent of octopamine or tyramine signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of octopamine or tyramine signalling pathway|positive regulation of octopamine/tyramine signaling pathway							mah	2010-09-29T09:27:19Z					biological_process											owl:Class	
GO:0016149	biolink:NamedThing	translation release factor activity, codon specific	A translation release factor that is specific for one or more particular termination codons; acts at the ribosomal A-site and require polypeptidyl-tRNA at the P-site.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0003747	biolink:NamedThing	translation release factor activity	Involved in catalyzing the release of a nascent polypeptide chain from a ribosome.	tmpzr1t_l9r_go_relaxed.owl												GO:0003749|GO:0003748		molecular_function											owl:Class	
GO:0000155	biolink:NamedThing	phosphorelay sensor kinase activity	Catalysis of the phosphorylation of a histidine residue in response to detection of an extracellular signal such as a chemical ligand or change in environment, to initiate a change in cell state or activity. The two-component sensor is a histidine kinase that autophosphorylates a histidine residue in its active site. The phosphate is then transferred to an aspartate residue in a downstream response regulator, to trigger a response.	tmpzr1t_l9r_go_relaxed.owl	two-component sensor activity|two-component system sensor activity|two-component sensor molecule				EC:2.7.3.-									molecular_function											owl:Class	
GO:0004673	biolink:NamedThing	protein histidine kinase activity	Catalysis of the reaction: ATP + protein L-histidine = ADP + protein phospho-L-histidine.	tmpzr1t_l9r_go_relaxed.owl	EnvZ|protein kinase (histidine) (ambiguous)|HK1|ATP:protein-L-histidine N-phosphotransferase activity|protein kinase (histidine)|protein histidine kinase (ambiguous)|Sln1p|histidine protein kinase (ambiguous)|protein-histidine kinase activity|HP165|histidine kinase activity|histidine protein kinase activity|histidine kinase (ambiguous)				EC:2.7.13.3|MetaCyc:2.7.13.3-RXN							GO:0008896		molecular_function											owl:Class	
GO:0030849	biolink:NamedThing	autosome	Any chromosome other than a sex chromosome.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Autosome	Note that this term is mainly relevant in organisms that have both sex chromosomes and non-sex-determining chromosomes in an individual organism.								cellular_component											owl:Class	
GO:0005694	biolink:NamedThing	chromosome	A structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information.	tmpzr1t_l9r_go_relaxed.owl	prophase chromosome|chromatid|interphase chromosome				Wikipedia:Chromosome	Chromosomes include parts that are not part of the chromatin.  Examples include the kinetochore.								cellular_component											owl:Class	
GO:0032576	biolink:NamedThing	O-linoleoyltransferase activity	Catalysis of the transfer of a linoleoyl ((9Z,12Z)-octadeca-9,12-dienoyl) group to an oxygen atom on the acceptor molecule.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0002561	biolink:NamedThing	basophil degranulation	The regulated exocytosis of secretory granules containing preformed mediators such as histamine, serotonin, and neutral proteases by a basophil.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0002276	biolink:NamedThing	basophil activation involved in immune response	A change in morphology and behavior of a basophil resulting from exposure to a cytokine, chemokine, soluble factor, or to (at least in mammals) an antigen which the basophil has specifically bound via IgE bound to Fc-epsilonRI receptors, leading to the initiation or perpetuation of an immune response.	tmpzr1t_l9r_go_relaxed.owl	basophil activation during immune response													biological_process											owl:Class	
GO:0070864	biolink:NamedThing	sperm individualization complex	A macromolecular complex that includes cytoskeletal components and part of the cell membrane. Forms at the nuclear end of a male germline syncytium, or cyst, and translocates the over the length of the syncytium in the course of sperm individualization. Each complex contains an array of 64 investment cones, one per nucleus, that move synchronously along the spermatogenic cyst.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-08-19T01:25:33Z					cellular_component											owl:Class	
GO:0090185	biolink:NamedThing	negative regulation of kidney development	Any process that decreases the rate, frequency or extent of kidney development. Kidney development is the process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of nephrogenesis							tb	2009-12-18T10:58:45Z					biological_process											owl:Class	
GO:0016303	biolink:NamedThing	1-phosphatidylinositol-3-kinase activity	Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol + ATP = a 1-phosphatidyl-1D-myo-inositol 3-phosphate + ADP + 2 H(+).	tmpzr1t_l9r_go_relaxed.owl	PI3K|phosphatidylinositol 3-kinase activity, class III|ATP:1-phosphatidyl-1D-myo-inositol 3-phosphotransferase activity|PtdIns-3-kinase activity|phosphatidylinositol 3-kinase, class I, catalyst activity|type I phosphatidylinositol kinase activity|phosphatidylinositol 3-kinase activity, class II|PI3-kinase activity|Vps34p|type III phosphoinositide 3-kinase activity|1-phosphatidylinositol 3-kinase activity|phosphatidylinositol 3-kinase activity, class I				RHEA:12709|Reactome:R-HSA-1675961|KEGG_REACTION:R03362|Reactome:R-HSA-109699|Reactome:R-HSA-5672012|Reactome:R-HSA-1675939|MetaCyc:1-PHOSPHATIDYLINOSITOL-3-KINASE-RXN|EC:2.7.1.137|Reactome:R-HSA-1676024|Reactome:R-HSA-6798174							GO:0004429		molecular_function											owl:Class	
GO:0052742	biolink:NamedThing	phosphatidylinositol kinase activity	Catalysis of the reaction: ATP + a phosphatidylinositol = ADP + a phosphatidylinositol phosphate.	tmpzr1t_l9r_go_relaxed.owl								ai	2011-09-14T01:21:47Z					molecular_function											owl:Class	
GO:0071677	biolink:NamedThing	positive regulation of mononuclear cell migration	Any process that increases the rate, frequency or extent of mononuclear cell migration. Mononuclear cell migration is the movement of a mononuclear cell within or between different tissues and organs of the body.	tmpzr1t_l9r_go_relaxed.owl	activation of mononuclear cell migration|upregulation of mononuclear cell migration|up-regulation of mononuclear cell migration|stimulation of mononuclear cell migration|up regulation of mononuclear cell migration							mah	2010-02-16T02:15:29Z					biological_process											owl:Class	
GO:1990489	biolink:NamedThing	anaerobic pectin catabolic process	The chemical reactions and pathways resulting in the breakdown of pectin, a polymer containing a backbone of alpha-1,4-linked D-galacturonic acid residues, in the absence of oxygen.	tmpzr1t_l9r_go_relaxed.owl	anaerobic pectin degradation							tt	2014-09-20T18:09:53Z					biological_process											owl:Class	
GO:0045490	biolink:NamedThing	pectin catabolic process	The chemical reactions and pathways resulting in the breakdown of pectin, a polymer containing a backbone of alpha-1,4-linked D-galacturonic acid residues.	tmpzr1t_l9r_go_relaxed.owl	pectin catabolism|pectin breakdown|pectin degradation													biological_process											owl:Class	
GO:1900652	biolink:NamedThing	regulation of demethylkotanin biosynthetic process	Any process that modulates the frequency, rate or extent of demethylkotanin biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of demethylkotanin formation|regulation of demethylkotanin synthesis|regulation of demethylkotanin anabolism|regulation of demethylkotanin biosynthesis							di	2012-05-22T04:07:18Z					biological_process											owl:Class	
GO:0031816	biolink:NamedThing	P2Y6 nucleotide receptor binding	Binding to a P2Y6 nucleotide receptor.	tmpzr1t_l9r_go_relaxed.owl	P2Y6 nucleotide receptor ligand													molecular_function											owl:Class	
GO:0050341	biolink:NamedThing	thymine dioxygenase activity	Catalysis of the reaction: thymine + 2-oxoglutarate + O2 = 5-hydroxymethyluracil + succinate + CO2.	tmpzr1t_l9r_go_relaxed.owl	thymine,2-oxoglutarate dioxygenase activity|thymine,2-oxoglutarate:oxygen oxidoreductase (7-hydroxylating)|thymine 7-hydroxylase activity|5-hydroxymethyluracil oxygenase activity|5-hydroxy-methyluracil dioxygenase activity				RHEA:10316|EC:1.14.11.6|MetaCyc:THYMINE-DIOXYGENASE-RXN									molecular_function											owl:Class	
GO:1903800	biolink:NamedThing	positive regulation of production of miRNAs involved in gene silencing by miRNA	Any process that activates or increases the frequency, rate or extent of production of miRNAs involved in gene silencing by miRNA.	tmpzr1t_l9r_go_relaxed.owl	activation of production of microRNAs involved in gene silencing by microRNA|upregulation of microRNA metabolism|up regulation of miRNA processing|up-regulation of microRNA-mediated gene silencing, production of microRNAs|activation of miRNA biogenesis|positive regulation of miRNA-mediated gene silencing, production of miRNAs|up regulation of production of miRNAs involved in gene silencing by miRNA|upregulation of production of microRNAs involved in gene silencing by microRNA|positive regulation of production of microRNAs involved in gene silencing by microRNA|positive regulation of microRNA metabolism|up regulation of microRNA-mediated gene silencing, production of microRNAs|up-regulation of microRNA metabolism|upregulation of miRNA biogenesis|up-regulation of miRNA-mediated gene silencing, production of miRNAs|up regulation of microRNA metabolic process|activation of microRNA metabolism|upregulation of miRNA-mediated gene silencing, production of miRNAs|up-regulation of microRNA biogenesis|activation of microRNA biogenesis|upregulation of microRNA biosynthetic process|upregulation of microRNA biogenesis|up regulation of miRNA-mediated gene silencing, production of miRNAs|activation of miRNA processing|up-regulation of miRNA biogenesis|upregulation of miRNA processing|up regulation of microRNA metabolism|activation of miRNA-mediated gene silencing, production of miRNAs|up regulation of gene silencing by miRNA, production of miRNAs|activation of microRNA metabolic process|up-regulation of microRNA biosynthesis|positive regulation of gene silencing by miRNA, production of miRNAs|up regulation of microRNA biosynthesis|up regulation of microRNA biosynthetic process|positive regulation of microRNA biosynthesis|positive regulation of microRNA biogenesis|up-regulation of production of microRNAs involved in gene silencing by microRNA|up-regulation of miRNA processing|activation of microRNA-mediated gene silencing, production of microRNAs|positive regulation of microRNA biosynthetic process|activation of gene silencing by miRNA, production of miRNAs|up-regulation of gene silencing by miRNA, production of miRNAs|positive regulation of miRNA processing|up regulation of microRNA biogenesis|up regulation of miRNA biogenesis|upregulation of microRNA metabolic process|upregulation of gene silencing by miRNA, production of miRNAs|up-regulation of microRNA metabolic process|positive regulation of miRNA biogenesis|upregulation of production of miRNAs involved in gene silencing by miRNA|activation of production of miRNAs involved in gene silencing by miRNA|up-regulation of microRNA biosynthetic process|activation of microRNA biosynthetic process|up regulation of production of microRNAs involved in gene silencing by microRNA|positive regulation of microRNA metabolic process|positive regulation of microRNA-mediated gene silencing, production of microRNAs|activation of microRNA biosynthesis|up-regulation of production of miRNAs involved in gene silencing by miRNA|upregulation of microRNA-mediated gene silencing, production of microRNAs|upregulation of microRNA biosynthesis							rph	2015-01-15T13:58:31Z					biological_process											owl:Class	
GO:2000637	biolink:NamedThing	positive regulation of gene silencing by miRNA	Any process that activates or increases the frequency, rate or extent of gene silencing by miRNA.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of gene silencing by microRNA|positive regulation of microRNA-mediated gene silencing|positive regulation of miRNA-mediated gene silencing							dph	2011-04-18T03:51:24Z					biological_process											owl:Class	
GO:0045780	biolink:NamedThing	positive regulation of bone resorption	Any process that activates or increases the frequency, rate or extent of bone resorption.	tmpzr1t_l9r_go_relaxed.owl	activation of bone resorption|stimulation of bone resorption|up-regulation of bone resorption|upregulation of bone resorption|up regulation of bone resorption													biological_process											owl:Class	
GO:0045124	biolink:NamedThing	regulation of bone resorption	Any process that modulates the frequency, rate or extent of bone tissue loss (resorption).	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1900787	biolink:NamedThing	naphtho-gamma-pyrone biosynthetic process	The chemical reactions and pathways resulting in the formation of naphtho-gamma-pyrone.	tmpzr1t_l9r_go_relaxed.owl	naphtho-gamma-pyrone anabolism|naphtho-gamma-pyrones biosynthetic process|naphtho-gamma-pyrones synthesis|naphtho-gamma-pyrone synthesis|naphtho-gamma-pyrones formation|naphtho-gamma-pyrone formation|naphtho-gamma-pyrone biosynthesis|naphtho-gamma-pyrones biosynthesis|naphtho-gamma-pyrones anabolism							di	2012-06-04T09:36:02Z					biological_process											owl:Class	
GO:1900785	biolink:NamedThing	naphtho-gamma-pyrone metabolic process	The chemical reactions and pathways involving naphtho-gamma-pyrone.	tmpzr1t_l9r_go_relaxed.owl	naphtho-gamma-pyrone metabolism|naphtho-gamma-pyrones metabolic process|naphtho-gamma-pyrones metabolism							di	2012-06-04T09:35:32Z					biological_process											owl:Class	
GO:1990520	biolink:NamedThing	separase-securin complex	A protein complex that includes separase (a protease which cleaves cohesin as part of chromosome separation) and securin, a protease inhibitor. Chromosome separation is inhibited until securin is degraded by the Anaphase Promoting Complex (APC).	tmpzr1t_l9r_go_relaxed.owl	Cut1-2 complex							vw	2014-10-23T10:34:52Z					cellular_component											owl:Class	
GO:1905369	biolink:NamedThing	endopeptidase complex	A protein complex which is capable of endopeptidase activity.	tmpzr1t_l9r_go_relaxed.owl						An example of this is PLAU in human (UniProt symbol P00749) in PMID:1689240 (inferred from direct assay).		bhm	2016-08-16T12:52:16Z					cellular_component											owl:Class	
GO:1990378	biolink:NamedThing	upstream stimulatory factor complex	A protein complex capable of sequence-specific DNA binding RNA polymerase II transcription factor activity through binding to a symmetrical DNA sequence (E-boxes) (5'-CACGTG-3'). Found in a variety of viral and cellular promoters.	tmpzr1t_l9r_go_relaxed.owl	USF1-USF2 heterodimer|USF2 homodimer|USF1 homodimer|USF complex					An example of this is USF1 in human (UniProt symbol P22415) in PMID:8576131 (inferred from direct assay).		bhm	2014-05-07T15:41:42Z					cellular_component											owl:Class	
GO:0035975	biolink:NamedThing	carbamoyl phosphate catabolic process	The chemical reactions and pathways resulting in the breakdown of carbamoyl phosphate, an intermediate in the urea cycle and other nitrogen compound metabolic pathways.	tmpzr1t_l9r_go_relaxed.owl	carbamoyl phosphate degradation|carbamoyl phosphate breakdown|carbamoyl phosphate catabolism							bf	2011-08-16T11:41:13Z					biological_process											owl:Class	
GO:0070408	biolink:NamedThing	carbamoyl phosphate metabolic process	The chemical reactions and pathways involving carbamoyl phosphate, an intermediate in the urea cycle and other nitrogen compound metabolic pathways.	tmpzr1t_l9r_go_relaxed.owl	carbamoyl phosphate metabolism				UM-BBD_pathwayID:bzn									biological_process											owl:Class	
GO:0072299	biolink:NamedThing	negative regulation of metanephric glomerulus development	Any process that decreases the rate, frequency or extent of metanephric glomerulus development, the progression of the metanephric glomerulus over time from its initial formation until its mature state. The metanephric glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney, or metanephros.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-04-09T05:03:41Z					biological_process											owl:Class	
GO:0072217	biolink:NamedThing	negative regulation of metanephros development	Any process that decreases the rate, frequency or extent of metanephros development. Metanephros development is the process whose specific outcome is the progression of the metanephros over time, from its formation to the mature structure. The metanephros is an organ that filters the blood and excretes the end products of body metabolism in the form of urine.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-03-18T01:45:48Z					biological_process											owl:Class	
GO:0150062	biolink:NamedThing	complement-mediated synapse pruning	Synaptic pruning mediated by complement system signalling.	tmpzr1t_l9r_go_relaxed.owl	synapse elimination|synapse clearance|complement-dependent synapse pruning|synapse disassembly|synapse removal							bc	2018-07-16T17:44:59Z					biological_process											owl:Class	
GO:0098883	biolink:NamedThing	synapse pruning	A cellular process that results in the controlled breakdown of synapse. After it starts the process is continuous until the synapse has disappeared.	tmpzr1t_l9r_go_relaxed.owl	synapse disassembly|synapse elimination|synapse removal|synapse clearance													biological_process											owl:Class	
GO:0043471	biolink:NamedThing	regulation of cellular carbohydrate catabolic process	Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of carbohydrates, carried out by individual cells.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1990878	biolink:NamedThing	cellular response to gastrin	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gastrin stimulus.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-10-07T17:38:14Z					biological_process											owl:Class	
GO:1901729	biolink:NamedThing	monensin A catabolic process	The chemical reactions and pathways resulting in the breakdown of monensin A.	tmpzr1t_l9r_go_relaxed.owl	monensin A breakdown|monensin degradation|monensin A catabolism|monensin breakdown|monensin A degradation|monensin catabolism							yaf	2013-01-09T11:55:49Z					biological_process											owl:Class	
GO:0000276	biolink:NamedThing	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)	All non-F1 subunits of the mitochondrial hydrogen-transporting ATP synthase, including integral and peripheral mitochondrial inner membrane proteins.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0048600	biolink:NamedThing	oocyte fate commitment	The process in which the developmental fate of a cell becomes restricted such that it will develop into an oocyte.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:2000737	biolink:NamedThing	negative regulation of stem cell differentiation	Any process that stops, prevents or reduces the frequency, rate or extent of stem cell differentiation.	tmpzr1t_l9r_go_relaxed.owl								yaf	2011-06-14T02:05:20Z					biological_process											owl:Class	
GO:0071826	biolink:NamedThing	ribonucleoprotein complex subunit organization	Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a ribonucleoprotein complex.	tmpzr1t_l9r_go_relaxed.owl	ribonucleoprotein complex subunit organisation|RNA-protein complex subunit organization|protein-RNA complex subunit organization							mah	2010-09-08T10:10:35Z					biological_process											owl:Class	
GO:0043933	biolink:NamedThing	protein-containing complex subunit organization	Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a protein complex.	tmpzr1t_l9r_go_relaxed.owl	protein complex subunit organisation|protein complex subunit organization|cellular macromolecular complex subunit organisation|macromolecular complex organization|macromolecular complex subunit organisation|cellular macromolecular complex organization|cellular macromolecular complex subunit organization|macromolecular complex subunit organization							mah	2010-09-08T10:01:42Z			GO:0034600|GO:0034621|GO:0071822		biological_process											owl:Class	
GO:0009898	biolink:NamedThing	cytoplasmic side of plasma membrane	The leaflet the plasma membrane that faces the cytoplasm and any proteins embedded or anchored in it or attached to its surface.	tmpzr1t_l9r_go_relaxed.owl	juxtamembrane|internal leaflet of plasma membrane|internal side of plasma membrane													cellular_component											owl:Class	
GO:0033623	biolink:NamedThing	regulation of integrin activation	Any process that modulates the frequency, rate, or extent of integrin activation.	tmpzr1t_l9r_go_relaxed.owl	regulation of integrin complex activation													biological_process											owl:Class	
GO:0140653	biolink:NamedThing	fumitremorgin C biosynthetic process	The chemical reactions and pathways resulting in the formation of fumitremorgin C.	tmpzr1t_l9r_go_relaxed.owl	fumitremorgin C synthesis|fumitremorgin C formation|fumitremorgin C biosynthesis|fumitremorgin C anabolism	https://github.com/geneontology/go-ontology/issues/21494						pg	2021-05-27T08:37:11Z					biological_process											owl:Class	
GO:0019287	biolink:NamedThing	isopentenyl diphosphate biosynthetic process, mevalonate pathway	The chemical reactions and pathways resulting in the formation of isopentenyl diphosphate, via the intermediate mevalonate. This pathway converts acetate, in the form of acetyl-CoA, to isopentenyl diphosphate (IPP), the fundamental unit in isoprenoid biosynthesis, through a series of mevalonate intermediates.	tmpzr1t_l9r_go_relaxed.owl	isopentenyl diphosphate formation, mevalonate pathway|Ac-MVA pathway|isopentenyl diphosphate synthesis, mevalonate pathway|isopentenyl diphosphate anabolism, mevalonate pathway|isopentenyl diphosphate biosynthetic process via mevalonate|acetate-mevalonate pathway													biological_process											owl:Class	
GO:0006084	biolink:NamedThing	acetyl-CoA metabolic process	The chemical reactions and pathways involving acetyl-CoA, a derivative of coenzyme A in which the sulfhydryl group is acetylated; it is a metabolite derived from several pathways (e.g. glycolysis, fatty acid oxidation, amino-acid catabolism) and is further metabolized by the tricarboxylic acid cycle. It is a key intermediate in lipid and terpenoid biosynthesis.	tmpzr1t_l9r_go_relaxed.owl	acetyl-CoA metabolism|acetyl coenzyme A metabolic process|acetyl coenzyme A metabolism													biological_process											owl:Class	
GO:0042918	biolink:NamedThing	alkanesulfonate transport	The directed movement of an alkanesulfonate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Alkanesulfonates are organic esters or salts of sulfonic acid containing an aliphatic hydrocarbon radical.	tmpzr1t_l9r_go_relaxed.owl	alkanesulphonate transport													biological_process											owl:Class	
GO:0046810	biolink:NamedThing	host cell extracellular matrix binding	Binding to the extracellular matrix of a host cell.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0050840	biolink:NamedThing	extracellular matrix binding	Binding to a component of the extracellular matrix.	tmpzr1t_l9r_go_relaxed.owl	extracellular matrix constituent binding|adhesive extracellular matrix constituent													molecular_function											owl:Class	
GO:0090684	biolink:NamedThing	contact chemoreceptor activity	A non-GPCR transmembrane signaling receptor activity that is responsible for contact chemoreception.	tmpzr1t_l9r_go_relaxed.owl	contact chemosensation receptor activity							tb	2016-05-20T15:53:01Z					molecular_function											owl:Class	
GO:0019612	biolink:NamedThing	4-toluenecarboxylate catabolic process	The chemical reactions and pathways resulting in the breakdown of 4-toluenecarboxylate, 4-methylbenzenecarboxylate, the anion of carboxylic acid attached to a methylbenzene molecule.	tmpzr1t_l9r_go_relaxed.owl	4-toluenecarboxylate breakdown|4-toluenecarboxylate degradation|p-toluate catabolic process|p-toluate catabolism|4-toluenecarboxylate catabolism				MetaCyc:4TOLCARBDEG-PWY									biological_process											owl:Class	
GO:0052083	biolink:NamedThing	suppression by symbiont of host cell-mediated immune response	Any process in which a symbiont stops, prevents, or reduces the frequency, rate or extent of the cell mediated immune response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	inhibition by symbiont of host cell-mediated immune response|negative regulation by organism of host cell-based immune response|down-regulation by symbiont of host cell-mediated immune response|down regulation by symbiont of host cell-mediated immune response|negative regulation by organism of cell-mediated immune response of other organism involved in symbiotic interaction|downregulation by symbiont of host cell-mediated immune response											GO:0052278		biological_process											owl:Class	
GO:0120069	biolink:NamedThing	positive regulation of stomach fundus smooth muscle contraction	Any process that increases the frequency, rate or extent of any stomach fundus smooth muscle contraction.	tmpzr1t_l9r_go_relaxed.owl								krc	2017-06-13T23:27:25Z					biological_process											owl:Class	
GO:1904306	biolink:NamedThing	positive regulation of gastro-intestinal system smooth muscle contraction	Any process that activates or increases the frequency, rate or extent of gastro-intestinal system smooth muscle contraction.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of gastro-intestinal system smooth muscle contraction|up regulation of gastro-intestinal system smooth muscle contraction|upregulation of gastro-intestinal system smooth muscle contraction|activation of gastro-intestinal system smooth muscle contraction							sl	2015-06-09T23:18:54Z					biological_process											owl:Class	
GO:1990588	biolink:NamedThing	FtsBL complex	A protein complex required for prokaryotic cell division (FtsZ-dependent cytokinesis). Part of the divisome. Assembled independently of the other divisome components in the cytoplasm prior to transport to the cell septum. In E. coli consists of FtsB and FtsL.	tmpzr1t_l9r_go_relaxed.owl	FtsB-FtsL complex					An example of this is FtsB in E. coli (P0A6S5) in PMID:15165235 (inferred from physical interaction).		bhm	2014-12-15T09:33:00Z					cellular_component											owl:Class	
GO:0008641	biolink:NamedThing	ubiquitin-like modifier activating enzyme activity	Catalysis of the activation of small proteins, such as ubiquitin or ubiquitin-like proteins, through the formation of an ATP-dependent high-energy thiolester bond.	tmpzr1t_l9r_go_relaxed.owl	small protein activating enzyme activity	https://github.com/geneontology/go-ontology/issues/14208										GO:0008642		molecular_function											owl:Class	
GO:1904905	biolink:NamedThing	negative regulation of endothelial cell-matrix adhesion via fibronectin	Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell-matrix adhesion via fibronectin.	tmpzr1t_l9r_go_relaxed.owl	downregulation of endothelial cell-matrix adhesion via fibronectin|inhibition of endothelial cell-matrix adhesion via fibronectin|down regulation of endothelial cell-matrix adhesion via fibronectin|down-regulation of endothelial cell-matrix adhesion via fibronectin							bc	2016-01-19T10:23:09Z					biological_process											owl:Class	
GO:0021847	biolink:NamedThing	ventricular zone neuroblast division	The proliferation of neuroblasts in the ventricular zone of the cerebral cortex. The neuronal progenitors of these cells will migrate radially.	tmpzr1t_l9r_go_relaxed.owl	neuroblast division in ventricular zone													biological_process											owl:Class	
GO:0021873	biolink:NamedThing	forebrain neuroblast division	The division of a neuroblast located in the forebrain. Neuroblast division gives rise to at least another neuroblast.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0047727	biolink:NamedThing	isobutyryl-CoA mutase activity	Catalysis of the reaction: isobutyryl-CoA = butanoyl-CoA.	tmpzr1t_l9r_go_relaxed.owl	2-methylpropanoyl-CoA CoA-carbonylmutase activity|isobutyryl coenzyme A mutase activity|butyryl-CoA:isobutyryl-CoA mutase activity				RHEA:13141|KEGG_REACTION:R01181|EC:5.4.99.13|MetaCyc:ISOBUTYRYL-COA-MUTASE-RXN									molecular_function											owl:Class	
GO:0016866	biolink:NamedThing	intramolecular transferase activity	Catalysis of the transfer of a functional group from one position to another within a single molecule.	tmpzr1t_l9r_go_relaxed.owl	mutase activity|intramolecular transferase activity, transferring other groups				EC:5.4.-.-									molecular_function											owl:Class	
GO:0033494	biolink:NamedThing	ferulate metabolic process	The chemical reactions and pathways involving ferulate, (2E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoate.	tmpzr1t_l9r_go_relaxed.owl	ferulate metabolism													biological_process											owl:Class	
GO:0035903	biolink:NamedThing	cellular response to immobilization stress	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of being rendered immobile.	tmpzr1t_l9r_go_relaxed.owl	cellular response to restraint stress|cellular response to immobilisation stress							bf	2011-06-22T09:47:44Z					biological_process											owl:Class	
GO:0098531	biolink:NamedThing	ligand-activated transcription factor activity	A DNA-binding transcription factor activity regulated by binding to a ligand and that modulates the transcription of specific gene sets. Examples include the lac and trp repressors in E.coli and steroid hormone receptors.	tmpzr1t_l9r_go_relaxed.owl	direct ligand regulated sequence-specific DNA binding transcription factor activity|transcription factor activity, direct ligand regulated sequence-specific DNA binding					For usage guidance, see comment in GO:0003700 ; DNA-binding transcription factor activity.		dos	2013-10-17T15:51:30Z					molecular_function											owl:Class	
GO:0140590	biolink:NamedThing	effector-mediated suppression of host defenses	A process mediated by a molecule secreted by a symbiont that results in the supression of a defense response. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	effector-mediated suppression of host defenses by symbiont	https://github.com/geneontology/go-ontology/issues/20813						pg	2021-02-08T07:26:05Z					biological_process											owl:Class	
GO:0051155	biolink:NamedThing	positive regulation of striated muscle cell differentiation	Any process that activates or increases the frequency, rate or extent of striated muscle cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of striated muscle cell differentiation|activation of striated muscle cell differentiation|up regulation of striated muscle cell differentiation|upregulation of striated muscle cell differentiation|stimulation of striated muscle cell differentiation													biological_process											owl:Class	
GO:0061058	biolink:NamedThing	regulation of peptidoglycan recognition protein signaling pathway	Any process that modulates the rate, frequency, or extent of the peptidoglycan recognition protein signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	regulation of peptidoglycan recognition protein signalling pathway							dph	2010-03-02T12:35:40Z					biological_process											owl:Class	
GO:0007077	biolink:NamedThing	mitotic nuclear membrane disassembly	The mitotic cell cycle process in which the controlled partial or complete breakdown of the nuclear membranes during occurs during mitosis.	tmpzr1t_l9r_go_relaxed.owl	mitotic nuclear envelope breakdown|NEB|local NEB|mitotic nuclear envelope catabolism|mitotic nuclear envelope disassembly|mitotic nuclear envelope degradation|nuclear envelope breakdown													biological_process											owl:Class	
GO:0015889	biolink:NamedThing	cobalamin transport	The directed movement of cobalamin (vitamin B12), a water-soluble vitamin characterized by possession of a corrin nucleus containing a cobalt atom, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	vitamin B12 transport													biological_process											owl:Class	
GO:1902204	biolink:NamedThing	positive regulation of hepatocyte growth factor receptor signaling pathway	Any process that activates or increases the frequency, rate or extent of hepatocyte growth factor receptor signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	activation of HGF receptor signaling pathway|activation of Met signaling pathway|positive regulation of HGF receptor signalling pathway|upregulation of HGF receptor signalling pathway|up regulation of HGF receptor signalling pathway|positive regulation of Met signaling pathway|upregulation of HGF receptor signaling pathway|up-regulation of Met signaling pathway|up-regulation of HGF receptor signaling pathway|positive regulation of HGF receptor signaling pathway|upregulation of hepatocyte growth factor receptor signaling pathway|up-regulation of HGF receptor signalling pathway|upregulation of Met signaling pathway|up-regulation of hepatocyte growth factor receptor signaling pathway|up regulation of Met signaling pathway|activation of hepatocyte growth factor receptor signaling pathway|up regulation of hepatocyte growth factor receptor signaling pathway|activation of HGF receptor signalling pathway|up regulation of HGF receptor signaling pathway							lb	2013-06-10T13:20:56Z					biological_process											owl:Class	
GO:1903646	biolink:NamedThing	positive regulation of chaperone-mediated protein folding	Any process that activates or increases the frequency, rate or extent of chaperone-mediated protein folding.	tmpzr1t_l9r_go_relaxed.owl	upregulation of chaperone-mediated protein folding|up-regulation of chaperone-mediated protein folding|activation of chaperone-mediated protein folding|up regulation of chaperone-mediated protein folding							pga	2014-11-21T15:25:44Z					biological_process											owl:Class	
GO:1903334	biolink:NamedThing	positive regulation of protein folding	Any process that activates or increases the frequency, rate or extent of protein folding.	tmpzr1t_l9r_go_relaxed.owl	up regulation of chaperone activity|up regulation of co-chaperone activity|positive regulation of protein complex assembly, multichaperone pathway|up-regulation of co-chaperonin activity|up regulation of protein folding|up-regulation of co-chaperone activity|upregulation of chaperonin-mediated tubulin folding|activation of protein complex assembly, multichaperone pathway|up-regulation of alpha-tubulin folding|upregulation of protein folding|upregulation of co-chaperonin activity|activation of co-chaperone activity|upregulation of chaperonin ATPase activity|upregulation of non-chaperonin molecular chaperone ATPase activity|upregulation of glycoprotein-specific chaperone activity|upregulation of chaperone activity|upregulation of alpha-tubulin folding|positive regulation of glycoprotein-specific chaperone activity|up regulation of non-chaperonin molecular chaperone ATPase activity|activation of chaperonin ATPase activity|up-regulation of non-chaperonin molecular chaperone ATPase activity|positive regulation of co-chaperone activity|up-regulation of protein folding|up-regulation of chaperone activity|positive regulation of chaperonin ATPase activity|up-regulation of beta-tubulin folding|activation of chaperone activity|upregulation of beta-tubulin folding|up regulation of alpha-tubulin folding|positive regulation of alpha-tubulin folding|activation of protein folding|activation of non-chaperonin molecular chaperone ATPase activity|positive regulation of co-chaperonin activity|activation of glycoprotein-specific chaperone activity|activation of chaperonin-mediated tubulin folding|activation of beta-tubulin folding|up regulation of chaperonin-mediated tubulin folding|positive regulation of beta-tubulin folding|up regulation of beta-tubulin folding|up regulation of glycoprotein-specific chaperone activity|activation of alpha-tubulin folding|positive regulation of chaperonin-mediated tubulin folding|positive regulation of non-chaperonin molecular chaperone ATPase activity|up-regulation of chaperonin ATPase activity|up-regulation of chaperonin-mediated tubulin folding|upregulation of co-chaperone activity|activation of co-chaperonin activity|upregulation of protein complex assembly, multichaperone pathway|up regulation of protein complex assembly, multichaperone pathway|up regulation of chaperonin ATPase activity|up regulation of co-chaperonin activity|up-regulation of glycoprotein-specific chaperone activity|positive regulation of chaperone activity|up-regulation of protein complex assembly, multichaperone pathway							vw	2014-08-18T13:14:50Z					biological_process											owl:Class	
GO:2001058	biolink:NamedThing	D-tagatose 6-phosphate metabolic process	The chemical reactions and pathways involving a D-tagatose 6-phosphate.	tmpzr1t_l9r_go_relaxed.owl	D-tagatose 6-phosphate metabolism							jl	2011-09-09T03:21:28Z					biological_process											owl:Class	
GO:0033974	biolink:NamedThing	nucleoside phosphoacylhydrolase activity	Catalysis of the hydrolysis of mixed phospho-anhydride bonds.	tmpzr1t_l9r_go_relaxed.owl	nucleoside-5'-phosphoacylate acylhydrolase activity				MetaCyc:3.6.1.24-RXN|EC:3.6.1.24									molecular_function											owl:Class	
GO:0140517	biolink:NamedThing	protein-RNA adaptor activity	The binding activity of a protein that brings together another protein and an RNA, permitting those molecules to function in a coordinated way.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/19409						pg	2020-09-11T09:12:05Z					molecular_function											owl:Class	
GO:0030674	biolink:NamedThing	protein-macromolecule adaptor activity	The binding activity of a protein that brings together two or more macromolecules in contact, permitting those molecules to function in a coordinated way. The adaptor can bring together two proteins, or a protein and another macromolecule such as a lipid or a nucleic acid.	tmpzr1t_l9r_go_relaxed.owl	protein-protein adaptor|protein binding, bridging	https://github.com/geneontology/go-ontology/issues/19409|https://github.com/geneontology/go-ontology/issues/18655												molecular_function											owl:Class	
GO:0050611	biolink:NamedThing	arsenate reductase (azurin) activity	Catalysis of the reaction: H(2)O + arsenite + 2 oxidized azurin = 2 H(+) + 2 reduced azurin + arsenate.	tmpzr1t_l9r_go_relaxed.owl	arsenite:azurin oxidoreductase activity|arsenite oxidase activity				EC:1.20.9.1|RHEA:18701|MetaCyc:1.20.98.1-RXN|UM-BBD_reactionID:r0634							GO:0018691		molecular_function											owl:Class	
GO:0052882	biolink:NamedThing	oxidoreductase activity, acting on phosphorus or arsenic in donors, with a copper protein as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which a phosphorus- or arsenic-containing group acts as a hydrogen or electron donor and reduces a copper protein.	tmpzr1t_l9r_go_relaxed.owl					EC:1.20.9.-									molecular_function											owl:Class	
GO:0042015	biolink:NamedThing	interleukin-20 binding	Binding to interleukin-20.	tmpzr1t_l9r_go_relaxed.owl	IL-20 binding													molecular_function											owl:Class	
GO:0060251	biolink:NamedThing	regulation of glial cell proliferation	Any process that modulates the frequency, rate or extent of glial cell proliferation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0048681	biolink:NamedThing	negative regulation of axon regeneration	Any process that stops, prevents, or reduces the frequency, rate or extent of axon regeneration.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of axon regeneration|down regulation of axon regeneration|inhibition of axon regeneration|downregulation of axon regeneration													biological_process											owl:Class	
GO:0043311	biolink:NamedThing	positive regulation of eosinophil degranulation	Any process that activates or increases the frequency, rate or extent of eosinophil degranulation.	tmpzr1t_l9r_go_relaxed.owl	stimulation of eosinophil degranulation|up-regulation of eosinophil degranulation|positive regulation of eosinophil granule exocytosis|activation of eosinophil degranulation|upregulation of eosinophil degranulation|up regulation of eosinophil degranulation													biological_process											owl:Class	
GO:0002872	biolink:NamedThing	negative regulation of natural killer cell tolerance induction	Any process that stops, prevents, or reduces the frequency, rate, or extent of natural killer cell tolerance induction.	tmpzr1t_l9r_go_relaxed.owl	downregulation of natural killer cell tolerance induction|down-regulation of natural killer cell tolerance induction|down regulation of natural killer cell tolerance induction|inhibition of natural killer cell tolerance induction|negative regulation of NK cell tolerance induction													biological_process											owl:Class	
GO:0103117	biolink:NamedThing	UDP-3-O-acyl-N-acetylglucosamine deacetylase activity	Catalysis of the reaction: UDP-3-O-[(3R)-3-hydroxytetradecanoyl]-N-acetylglucosamine(2-) + H2O <=> UDP-3-O-[(3R)-3-hydroxytetradecanoyl]-alpha-D-glucosamine(1-) + acetate.	tmpzr1t_l9r_go_relaxed.owl					EC:3.5.1.108|MetaCyc:UDPACYLGLCNACDEACETYL-RXN|RHEA:25209									molecular_function											owl:Class	
GO:1904300	biolink:NamedThing	positive regulation of transcytosis	Any process that activates or increases the frequency, rate or extent of transcytosis.	tmpzr1t_l9r_go_relaxed.owl	up regulation of transcytosis|activation of transcytosis|upregulation of transcytosis|up-regulation of transcytosis							sl	2015-06-09T22:53:38Z					biological_process											owl:Class	
GO:2001170	biolink:NamedThing	negative regulation of ATP biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of ATP biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of ATP synthesis|negative regulation of ATP formation|negative regulation of ATP anabolism|negative regulation of ATP regeneration|negative regulation of ATP biosynthesis							kmv	2011-10-26T03:18:13Z					biological_process											owl:Class	
GO:2001169	biolink:NamedThing	regulation of ATP biosynthetic process	Any process that modulates the frequency, rate or extent of ATP biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of ATP regeneration|regulation of ATP biosynthesis|regulation of ATP anabolism|regulation of ATP synthesis|regulation of ATP formation							kmv	2011-10-26T03:18:03Z					biological_process											owl:Class	
GO:1905451	biolink:NamedThing	positive regulation of Fc-gamma receptor signaling pathway involved in phagocytosis	Any process that activates or increases the frequency, rate or extent of Fc-gamma receptor signaling pathway involved in phagocytosis.	tmpzr1t_l9r_go_relaxed.owl	activation of Fc-gamma receptor signalling pathway involved in phagocytosis|up-regulation of Fc-gamma receptor signaling pathway involved in phagocytosis|positive regulation of Fcgamma receptor-mediated phagocytosis|up regulation of IgG-mediated phagocytosis|up regulation of Fcgamma receptor-mediated phagocytosis|activation of Fcgamma receptor-mediated phagocytosis|upregulation of Fc gamma receptor-dependent phagocytosis|activation of Fc gamma receptor-dependent phagocytosis|positive regulation of IgG-mediated phagocytosis|up regulation of Fc gamma receptor-dependent phagocytosis|up-regulation of IgG-mediated phagocytosis|up-regulation of Fcgamma receptor-mediated phagocytosis|upregulation of IgG-mediated phagocytosis|up-regulation of Fc-gamma receptor signalling pathway involved in phagocytosis|upregulation of Fc-gamma receptor signalling pathway involved in phagocytosis|upregulation of Fcgamma receptor-mediated phagocytosis|activation of IgG-mediated phagocytosis|activation of Fc-gamma receptor signaling pathway involved in phagocytosis|up-regulation of Fc gamma receptor-dependent phagocytosis|positive regulation of Fc-gamma receptor signalling pathway involved in phagocytosis|up regulation of Fc-gamma receptor signalling pathway involved in phagocytosis|positive regulation of Fc gamma receptor-dependent phagocytosis|up regulation of Fc-gamma receptor signaling pathway involved in phagocytosis|upregulation of Fc-gamma receptor signaling pathway involved in phagocytosis							sl	2016-09-15T19:42:06Z					biological_process											owl:Class	
GO:0003835	biolink:NamedThing	beta-galactoside alpha-2,6-sialyltransferase activity	Catalysis of the reaction: CMP-N-acetylneuraminate + beta-D-galactosyl-(1->4)-acetyl-beta-D-glucosamine = CMP + alpha-N-acetylneuraminyl-(2->6)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosamine.	tmpzr1t_l9r_go_relaxed.owl	beta-galactosamide alpha-2,6-sialyltransferase activity|CMP-N-acetylneuraminate:beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosamine alpha-2,6-N-acetylneuraminyltransferase activity|CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,6-sialyltransferase activity				Reactome:R-HSA-975902|MetaCyc:2.4.99.1-RXN|Reactome:R-HSA-977071|Reactome:R-HSA-4085033|RHEA:11836|Reactome:R-HSA-977228|EC:2.4.99.1									molecular_function											owl:Class	
GO:0047633	biolink:NamedThing	agmatine kinase activity	Catalysis of the reaction: agmatine + ATP = N(4)-phosphoagmatine + ADP + 3 H(+).	tmpzr1t_l9r_go_relaxed.owl	phosphagen phosphokinase activity|ATP:agmatine 4-N-phosphotransferase activity|ATP:agmatine N4-phosphotransferase activity				KEGG_REACTION:R01417|EC:2.7.3.10|MetaCyc:AGMATINE-KINASE-RXN|RHEA:15953									molecular_function											owl:Class	
GO:0004618	biolink:NamedThing	phosphoglycerate kinase activity	Catalysis of the reaction: 3-phospho-D-glycerate + ATP = 3-phospho-D-glyceroyl phosphate + ADP + H(+).	tmpzr1t_l9r_go_relaxed.owl	PGK|ATP:D-3-phosphoglycerate 1-phosphotransferase activity|3-phosphoglycerate kinase activity|phosphoglyceric acid kinase activity|ATP-3-phospho-D-glycerate-1-phosphotransferase activity|3-phosphoglyceric kinase activity|glycerate 3-phosphate kinase activity|phosphoglycerokinase activity|phosphoglyceric kinase activity|3-PGK|ATP:3-phospho-D-glycerate 1-phosphotransferase activity|3-phosphoglyceric acid phosphokinase activity|3-phosphoglycerate phosphokinase activity|3-phosphoglyceric acid kinase activity|glycerophosphate kinase activity				Reactome:R-HSA-71850|MetaCyc:PHOSGLYPHOS-RXN|EC:2.7.2.3|KEGG_REACTION:R01512|RHEA:14801|Reactome:R-HSA-70486									molecular_function											owl:Class	
GO:0002702	biolink:NamedThing	positive regulation of production of molecular mediator of immune response	Any process that activates or increases the frequency, rate, or extent of the production of molecular mediator of immune response.	tmpzr1t_l9r_go_relaxed.owl	upregulation of production of molecular mediator of immune response|up regulation of production of molecular mediator of immune response|up-regulation of production of molecular mediator of immune response|activation of production of molecular mediator of immune response|stimulation of production of molecular mediator of immune response													biological_process											owl:Class	
GO:0150017	biolink:NamedThing	basal proximal dendrite	Any dendrite in a dendritic tree that emerges near the basal pole of a neuron (e.g. in bipolar neurons, basal dendrites are either on the same side of the soma as the axon, or project toward the axon), and which is the closest to the cell body of the neuron (the soma).	tmpzr1t_l9r_go_relaxed.owl								bc	2017-12-21T12:17:00Z					cellular_component											owl:Class	
GO:0097585	biolink:NamedThing	dolichyl-phosphate-mannose-protein mannosyltransferase Pmt5p-Pmt3p dimer complex	A protein dimer complex that possesses dolichyl-phosphate-mannose-protein mannosyltransferase activity and, in S. cerevisiae, is composed of Pmt5p-Pmt3p.	tmpzr1t_l9r_go_relaxed.owl	Pmt5p-Pmt3p complex							pr	2014-03-02T18:18:28Z					cellular_component											owl:Class	
GO:1905484	biolink:NamedThing	negative regulation of motor neuron migration	Any process that stops, prevents or reduces the frequency, rate or extent of motor neuron migration.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of motor neuron migration|down regulation of motor neuron migration|inhibition of motor neuron migration|downregulation of motor neuron migration							hbye	2016-09-23T12:50:11Z					biological_process											owl:Class	
GO:1905483	biolink:NamedThing	regulation of motor neuron migration	Any process that modulates the frequency, rate or extent of motor neuron migration.	tmpzr1t_l9r_go_relaxed.owl								hbye	2016-09-23T12:49:54Z					biological_process											owl:Class	
GO:1903124	biolink:NamedThing	negative regulation of thioredoxin peroxidase activity	Any process that stops, prevents or reduces the frequency, rate or extent of thioredoxin peroxidase activity.	tmpzr1t_l9r_go_relaxed.owl	inhibition of thioredoxin peroxidase activity|downregulation of thiol peroxidase activity|inhibition of TPx activity|down-regulation of thiol peroxidase activity|downregulation of TrxPx activity|down-regulation of thioredoxin peroxidase activity|downregulation of TPx activity|negative regulation of thiol peroxidase activity|inhibition of thiol peroxidase activity|down-regulation of TrxPx activity|inhibition of TrxPx activity|down regulation of thioredoxin peroxidase activity|down regulation of TPx activity|negative regulation of TrxPx activity|downregulation of thioredoxin peroxidase activity|down-regulation of TPx activity|down regulation of thiol peroxidase activity|down regulation of TrxPx activity|negative regulation of TPx activity							bf	2014-06-18T11:03:26Z					biological_process											owl:Class	
GO:0086012	biolink:NamedThing	membrane depolarization during cardiac muscle cell action potential	The process in which cardiac muscle cell membrane potential changes in the depolarizing direction from the negative resting potential towards the positive membrane potential that will be the peak of the action potential.	tmpzr1t_l9r_go_relaxed.owl								tb	2011-11-10T08:20:33Z					biological_process											owl:Class	
GO:0040001	biolink:NamedThing	establishment of mitotic spindle localization	The cell cycle process in which the directed movement of the mitotic spindle to a specific location in the cell occurs.	tmpzr1t_l9r_go_relaxed.owl	spindle positioning during mitosis|spindle positioning involved in mitotic cell cycle|mitotic spindle positioning or orientation|mitotic spindle positioning and orientation|establishment of mitotic spindle localisation|mitotic spindle positioning											GO:0030608|GO:0030606|GO:0030610|GO:0030605|GO:0018986		biological_process											owl:Class	
GO:1901307	biolink:NamedThing	positive regulation of spermidine biosynthetic process	Any process that activates or increases the frequency, rate or extent of spermidine biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	upregulation of spermidine synthesis|activation of spermidine anabolism|activation of spermidine biosynthetic process|up regulation of spermidine anabolism|positive regulation of spermidine synthesis|up regulation of spermidine biosynthetic process|positive regulation of spermidine formation|upregulation of spermidine biosynthesis|up regulation of spermidine formation|positive regulation of spermidine biosynthesis|upregulation of spermidine biosynthetic process|up regulation of spermidine biosynthesis|activation of spermidine biosynthesis|upregulation of spermidine anabolism|up-regulation of spermidine synthesis|up-regulation of spermidine biosynthetic process|upregulation of spermidine formation|up-regulation of spermidine anabolism|up regulation of spermidine synthesis|up-regulation of spermidine biosynthesis|up-regulation of spermidine formation|activation of spermidine synthesis|positive regulation of spermidine anabolism|activation of spermidine formation							pm	2012-08-21T14:02:58Z					biological_process											owl:Class	
GO:1990259	biolink:NamedThing	histone-glutamine methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + (histone)-glutamine = S-adenosyl-L-homocysteine + (histone)-N5-methyl-glutamine.	tmpzr1t_l9r_go_relaxed.owl								sp	2014-01-02T15:10:29Z					molecular_function											owl:Class	
GO:0036009	biolink:NamedThing	protein-glutamine N-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + protein L-glutamine = S-adenosyl-L-homocysteine + protein N-methyl-L-glutamine.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-6800138			bf	2011-10-03T02:27:05Z					molecular_function											owl:Class	
GO:0032589	biolink:NamedThing	neuron projection membrane	The portion of the plasma membrane surrounding a neuron projection.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0031256	biolink:NamedThing	leading edge membrane	The portion of the plasma membrane surrounding the leading edge of a motile cell.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0018148	biolink:NamedThing	RNA-protein covalent cross-linking via peptidyl-tyrosine	The formation of a covalent cross-link between RNA and a peptidyl-tyrosine residue by the formation of O4'-(phospho-5'-RNA)-L-tyrosine.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0249									biological_process											owl:Class	
GO:0047241	biolink:NamedThing	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity	Catalysis of the reaction: lipopolysaccharide + UDP-N-acetylmannosaminouronate = N-acetyl-beta-D-mannosaminouronosyl-1,4-lipopolysaccharide + UDP.	tmpzr1t_l9r_go_relaxed.owl	uridine diphosphoacetylmannosaminuronate-acetylglucosaminylpyrophosphorylundecaprenol acetylmannosaminuronosyltransferase activity|LPS N-acetylmannosaminouronosyltransferase activity|UDP-N-acetyl-beta-D-mannosaminouronate:lipopolysaccharide N-acetyl-beta-D-mannosaminouronosyltransferase activity|ManNAcA transferase activity				MetaCyc:2.4.1.180-RXN|RHEA:28366|EC:2.4.1.180									molecular_function											owl:Class	
GO:0051231	biolink:NamedThing	spindle elongation	The cell cycle process in which the distance is lengthened between poles of the spindle.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:2000212	biolink:NamedThing	negative regulation of glutamate metabolic process	Any process that stops, prevents, or reduces the frequency, rate or extent of glutamate metabolic process.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of glutamic acid metabolic process|negative regulation of glutamic acid metabolism|negative regulation of glutamate metabolism							mah	2010-11-03T02:43:55Z					biological_process											owl:Class	
GO:0045763	biolink:NamedThing	negative regulation of cellular amino acid metabolic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving amino acid.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of amino acid metabolic process|negative regulation of amino acid metabolism|inhibition of amino acid metabolic process|down regulation of amino acid metabolic process|downregulation of amino acid metabolic process													biological_process											owl:Class	
GO:0016063	biolink:NamedThing	rhodopsin biosynthetic process	The chemical reactions and pathways resulting in the formation of rhodopsin, a brilliant purplish-red, light-sensitive visual pigment found in the rod cells of the retinas.	tmpzr1t_l9r_go_relaxed.owl	rhodopsin anabolism|rhodopsin formation|rhodopsin synthesis|rhodopsin biosynthesis													biological_process											owl:Class	
GO:0006726	biolink:NamedThing	eye pigment biosynthetic process	The chemical reactions and pathways resulting in the formation of eye pigments, any general or particular coloring matter in living organisms, found or utilized in the eye.	tmpzr1t_l9r_go_relaxed.owl	eye pigment synthesis|eye pigment anabolism|eye pigment formation|eye pigment biosynthesis													biological_process											owl:Class	
GO:0090500	biolink:NamedThing	endocardial cushion to mesenchymal transition	A transition where an endocardial cushion cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell.	tmpzr1t_l9r_go_relaxed.owl								tb	2012-10-22T11:51:44Z					biological_process											owl:Class	
GO:0061572	biolink:NamedThing	actin filament bundle organization	A process that results in the assembly, arrangement of constituent parts, or disassembly of an actin filament bundle.	tmpzr1t_l9r_go_relaxed.owl	actin filament cable organization							dph	2013-08-02T11:24:11Z					biological_process											owl:Class	
GO:0031665	biolink:NamedThing	negative regulation of lipopolysaccharide-mediated signaling pathway	Any process that stops, prevents, or reduces the frequency, rate or extent of signaling in response to detection of lipopolysaccharide.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of LPS-mediated signaling pathway|negative regulation of lipopolysaccharide-mediated signalling pathway|down-regulation of lipopolysaccharide-mediated signaling pathway|inhibition of lipopolysaccharide-mediated signaling pathway|downregulation of lipopolysaccharide-mediated signaling pathway|down regulation of lipopolysaccharide-mediated signaling pathway													biological_process											owl:Class	
GO:0018486	biolink:NamedThing	2-butanone oxidase activity	Catalysis of the reaction: methyl ethyl ketone + O2 = H2O + ethyl acetate.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0169									molecular_function											owl:Class	
GO:1900002	biolink:NamedThing	positive regulation of anthocyanin catabolic process	Any process that activates or increases the frequency, rate or extent of anthocyanin catabolic process.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of anthocyanin catabolism|positive regulation of anthocyanin degradation|up regulation of anthocyanin breakdown|up regulation of anthocyanin degradation|up regulation of anthocyanin catabolism|up regulation of anthocyanin catabolic process|positive regulation of anthocyanin breakdown							tb	2011-12-20T07:12:15Z					biological_process											owl:Class	
GO:0032165	biolink:NamedThing	prospore septin filament array	Arrays of septin filaments, or bars, found in a series of filamentous structures; observed in the prospore membrane during spore formation.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0032160	biolink:NamedThing	septin filament array	Arrays of septin filaments, or bars, found in a series of filamentous structures. Such structures have been observed in the prospore membrane during spore formation in S. cerevisiae and in the chlamydospore membrane during chlamydospore formation in C. albicans.	tmpzr1t_l9r_go_relaxed.owl	septin bar													cellular_component											owl:Class	
GO:0030880	biolink:NamedThing	RNA polymerase complex	Any complex that possesses RNA polymerase activity; generally comprises a catalytic subunit and one or more additional subunits.	tmpzr1t_l9r_go_relaxed.owl	multisubunit RNA polymerase													cellular_component											owl:Class	
GO:0071312	biolink:NamedThing	cellular response to alkaloid	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alkaloid stimulus. Alkaloids are a large group of nitrogenous substances found in naturally in plants, many of which have extracts that are pharmacologically active.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-12-10T04:50:58Z					biological_process											owl:Class	
GO:2001135	biolink:NamedThing	regulation of endocytic recycling	Any process that modulates the frequency, rate or extent of endocytic recycling.	tmpzr1t_l9r_go_relaxed.owl	regulation of retrograde transport of endocytic vesicles							kmv	2011-10-14T03:34:36Z					biological_process											owl:Class	
GO:0035028	biolink:NamedThing	leading edge cell fate determination	The process in which a cell becomes capable of differentiating autonomously into a leading edge cell regardless of its environment; upon determination, the cell fate cannot be reversed.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0048159	biolink:NamedThing	primary oocyte stage	The stage in oogenesis when the oocyte has a nucleus slightly larger than those of the adjacent cells and is surrounded by a layer of loose squamous epithelial cells.	tmpzr1t_l9r_go_relaxed.owl	mammalian oogenesis stage 2													biological_process											owl:Class	
GO:0032959	biolink:NamedThing	inositol trisphosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of inositol trisphosphate, 1,2,3,4,5,6-cyclohexanehexol, with three phosphate groups attached.	tmpzr1t_l9r_go_relaxed.owl	myo-inositol trisphosphate biosynthetic process|inositol trisphosphate formation|inositol trisphosphate synthesis|IP3 biosynthetic process|inositol trisphosphate biosynthesis|inositol trisphosphate anabolism|IP3 biosynthesis													biological_process											owl:Class	
GO:0046095	biolink:NamedThing	deoxyinosine biosynthetic process	The chemical reactions and pathways resulting in the formation of deoxyinosine, hypoxanthine deoxyriboside.	tmpzr1t_l9r_go_relaxed.owl	deoxyinosine anabolism|deoxyinosine synthesis|deoxyinosine biosynthesis|deoxyinosine formation													biological_process											owl:Class	
GO:0046123	biolink:NamedThing	purine deoxyribonucleoside biosynthetic process	The chemical reactions and pathways resulting in the formation of any purine deoxyribonucleoside, one of a family of organic molecules consisting of a purine base covalently bonded to a sugar deoxyribose (a deoxyribonucleoside).	tmpzr1t_l9r_go_relaxed.owl	purine deoxyribonucleoside biosynthesis|purine deoxyribonucleoside anabolism|purine deoxyribonucleoside synthesis|purine deoxyribonucleoside formation													biological_process											owl:Class	
GO:0106292	biolink:NamedThing	superoxide-generating NADPH oxidase activity	Catalysis of the reaction: NADPH + 2 O2 = H(+) + NADP(+) + 2 superoxide.	tmpzr1t_l9r_go_relaxed.owl					RHEA:63180			hjd	2020-08-19T15:58:36Z					molecular_function											owl:Class	
GO:0016175	biolink:NamedThing	superoxide-generating NAD(P)H oxidase activity	Catalysis of the reaction: NAD(P)H + O2 = NAD(P)H + O2-.	tmpzr1t_l9r_go_relaxed.owl	cytochrome B-245				Reactome:R-HSA-5668718|Reactome:R-HSA-1222376|Reactome:R-HSA-1236967|Reactome:R-HSA-1497810|EC:1.6.3.-|Reactome:R-HSA-6807557|Reactome:R-HSA-9673797|Reactome:R-HSA-6789092|Reactome:R-HSA-5218841|Reactome:R-HSA-5668629|Reactome:R-HSA-5668731									molecular_function											owl:Class	
GO:1902938	biolink:NamedThing	regulation of intracellular calcium activated chloride channel activity	Any process that modulates the frequency, rate or extent of intracellular calcium activated chloride channel activity.	tmpzr1t_l9r_go_relaxed.owl								als	2014-04-28T08:49:08Z					biological_process											owl:Class	
GO:0045814	biolink:NamedThing	negative regulation of gene expression, epigenetic	An epigenetic process that stops, prevents or reduces the rate of gene expression by remodelling of chromatin by either modifying the chromatin fiber, the nucleosomal histones, or the DNA.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of gene expression, epigenetic|gene silencing|down regulation of gene expression, epigenetic|inhibition of gene expression, epigenetic|downregulation of gene expression, epigenetic	https://github.com/geneontology/go-ontology/issues/22201												biological_process											owl:Class	
GO:0090037	biolink:NamedThing	positive regulation of protein kinase C signaling	Any process that increases the frequency, rate, or extent of a series of reactions, mediated by the intracellular serine/threonine kinase protein kinase C, which occurs as a result of a single trigger reaction or compound.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of protein kinase C signalling cascade|positive regulation of protein kinase C signaling cascade							tb	2009-08-03T11:28:44Z					biological_process											owl:Class	
GO:0090036	biolink:NamedThing	regulation of protein kinase C signaling	Any process that modulates the frequency, rate, or extent of a series of reactions, mediated by the intracellular serine/threonine kinase protein kinase C, which occurs as a result of a single trigger reaction or compound.	tmpzr1t_l9r_go_relaxed.owl	regulation of protein kinase C signalling cascade|regulation of protein kinase C signaling cascade							tb	2009-08-03T11:27:26Z					biological_process											owl:Class	
GO:0009079	biolink:NamedThing	pyruvate family amino acid biosynthetic process	The chemical reactions and pathways resulting in the formation of any amino acid that requires pyruvate for its synthesis, e.g. alanine.	tmpzr1t_l9r_go_relaxed.owl	pyruvate family amino acid biosynthesis|pyruvate family amino acid synthesis|pyruvate family amino acid formation|pyruvate family amino acid anabolism													biological_process											owl:Class	
GO:0051144	biolink:NamedThing	propanediol catabolic process	The chemical reactions and pathways resulting in the breakdown of propanediol, a sweet, colorless, viscous, hygroscopic liquid with the formula CH3-CHOH-CH2OH.	tmpzr1t_l9r_go_relaxed.owl	1,2-dihydroxypropane catabolism|1,2-dihydroxypropane catabolic process|propylene glycol catabolic process|propylene glycol catabolism|propanediol catabolism|propanediol breakdown|propanediol degradation													biological_process											owl:Class	
GO:1901857	biolink:NamedThing	positive regulation of cellular respiration	Any process that activates or increases the frequency, rate or extent of cellular respiration.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of respiration|upregulation of cellular respiration|activation of oxidative metabolism|up-regulation of oxidative metabolic process|activation of respiration|up regulation of cellular respiration|up regulation of respiration|positive regulation of oxidative metabolism|activation of cellular respiration|upregulation of oxidative metabolic process|up regulation of oxidative metabolic process|up regulation of oxidative metabolism|up-regulation of oxidative metabolism|upregulation of oxidative metabolism|positive regulation of oxidative metabolic process|activation of oxidative metabolic process|upregulation of respiration|up-regulation of respiration|up-regulation of cellular respiration							yaf	2013-02-01T09:56:28Z					biological_process											owl:Class	
GO:0045610	biolink:NamedThing	regulation of hemocyte differentiation	Any process that modulates the frequency, rate or extent of hemocyte differentiation.	tmpzr1t_l9r_go_relaxed.owl	regulation of arthropod blood cell differentiation													biological_process											owl:Class	
GO:0045503	biolink:NamedThing	dynein light chain binding	Binding to a light chain of the dynein complex.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0006083	biolink:NamedThing	acetate metabolic process	The chemical reactions and pathways involving acetate, the anion of acetic acid.	tmpzr1t_l9r_go_relaxed.owl	acetate metabolism													biological_process											owl:Class	
GO:0080127	biolink:NamedThing	fruit septum development	The process whose specific outcome is the progression of the fruit septum over time, from its formation to the mature structure. The fruit septum is a thin partition or membrane that divides a cavity or a mass of tissue in the fruit.	tmpzr1t_l9r_go_relaxed.owl								dhl	2009-04-28T04:37:19Z					biological_process											owl:Class	
GO:0035509	biolink:NamedThing	negative regulation of myosin-light-chain-phosphatase activity	Any process that stops, prevents, or reduces the frequency, rate or extent of myosin-light-chain-phosphatase activity.	tmpzr1t_l9r_go_relaxed.owl								bf	2010-04-30T10:56:34Z					biological_process											owl:Class	
GO:0005786	biolink:NamedThing	signal recognition particle, endoplasmic reticulum targeting	A ribonucleoprotein particle of 325 kDa composed of a 7S (300 nucleotide) RNA molecule and a complex of six different polypeptides. This binds both to the N-terminal signal peptide for proteins destined for the endoplasmic reticulum as they emerge from the large ribosomal subunit and also to the ribosome. This binding arrests further translation thereby preventing the proteins from being released into the cytosol. The SRP-ribosome complex then diffuses to the endoplasmic reticulum where it is bound to the signal recognition particle receptor, which allows resumption of protein synthesis and facilitates the passage of the growing polypeptide chain through the translocon. Through a process involving GTP hydrolysis, the SRP-SRP receptor complex dissociates and SRP returns to the cytosol. Of the six polypeptides of SRP the 54 kDa subunit (SRP54) is the central player. It contains an N-terminal GTPase domain and a C-terminal domain that binds directly to the signal peptide and the SRP RNA. Examples of this component are found in Mus musculus, Saccharomyces cerevisiae and Arabidopsis thaliana.	tmpzr1t_l9r_go_relaxed.owl	signal sequence receptor complex|SRP				Wikipedia:Signal_recognition_particle							GO:0005855		cellular_component											owl:Class	
GO:0048500	biolink:NamedThing	signal recognition particle	A complex of protein and RNA which facilitates translocation of proteins across membranes.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Signal_recognition_particle									cellular_component											owl:Class	
GO:0042077	biolink:NamedThing	protein phosphate-linked glycosylation via serine	The glycosylation of peptidyl-serine through a phosphoester bond forming, for example, GlcNAc-alpha-1-P-Ser residues.	tmpzr1t_l9r_go_relaxed.owl	protein amino acid phosphate-linked glycosylation via serine													biological_process											owl:Class	
GO:0005135	biolink:NamedThing	interleukin-3 receptor binding	Binding to an interleukin-3 receptor.	tmpzr1t_l9r_go_relaxed.owl	IL-3|interleukin-3 receptor ligand													molecular_function											owl:Class	
GO:0097279	biolink:NamedThing	histamine secretion mediated by IgE immunoglobulin	Histamine release triggered by the binding of an antigen to an IgE immunoglobulin bound to the cell surface. An example is mast cell histamine degranulation as a result of exposure of mast cell-bound IgE to alder tree pollen.	tmpzr1t_l9r_go_relaxed.owl	histamine secretion mediated by IgE antibody|Ig-mediated histamine release							pr	2012-03-22T06:42:13Z					biological_process											owl:Class	
GO:0097280	biolink:NamedThing	histamine secretion mediated by immunoglobulin	Histamine release triggered by the binding of an antigen to an immunoglobulin bound to the cell surface.	tmpzr1t_l9r_go_relaxed.owl								pr	2012-03-26T01:30:25Z					biological_process											owl:Class	
GO:2000572	biolink:NamedThing	positive regulation of interleukin-4-dependent isotype switching to IgE isotypes	Any process that activates or increases the frequency, rate or extent of interleukin-4-dependent isotype switching to IgE isotypes.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of IL-4-dependent isotype switching to IgE isotypes							ebc	2011-04-03T09:20:18Z					biological_process											owl:Class	
GO:0002092	biolink:NamedThing	positive regulation of receptor internalization	Any process that activates or increases the frequency, rate or extent of receptor internalization.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of receptor internalization|stimulation of receptor internalization|activation of receptor internalization|upregulation of receptor internalization|up regulation of receptor internalization													biological_process											owl:Class	
GO:0018091	biolink:NamedThing	peptidyl-asparagine racemization	The racemization of peptidyl-asparagine.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0196							GO:0019127|GO:0018373		biological_process											owl:Class	
GO:0051985	biolink:NamedThing	negative regulation of chromosome segregation	Any process that stops, prevents, or reduces the frequency, rate or extent of chromosome segregation, the process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of chromosome segregation|downregulation of chromosome segregation|down regulation of chromosome segregation|inhibition of chromosome segregation													biological_process											owl:Class	
GO:1901158	biolink:NamedThing	neomycin biosynthetic process	The chemical reactions and pathways resulting in the formation of neomycin.	tmpzr1t_l9r_go_relaxed.owl	neomycin anabolism|neomycin synthesis|neomycin formation|neomycin biosynthesis							yaf	2012-07-17T04:28:28Z					biological_process											owl:Class	
GO:0030502	biolink:NamedThing	negative regulation of bone mineralization	Any process that stops, prevents, or reduces the frequency, rate or extent of bone mineralization.	tmpzr1t_l9r_go_relaxed.owl	inhibition of bone mineralization|down regulation of bone mineralization|downregulation of bone mineralization|down-regulation of bone mineralization													biological_process											owl:Class	
GO:0030500	biolink:NamedThing	regulation of bone mineralization	Any process that modulates the frequency, rate or extent of bone mineralization.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:2000113	biolink:NamedThing	negative regulation of cellular macromolecule biosynthetic process	Any process that stops, prevents, or reduces the frequency, rate or extent of cellular macromolecule biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of cellular macromolecule synthesis|negative regulation of cellular biopolymer biosynthetic process|negative regulation of cellular macromolecule anabolism|negative regulation of cellular macromolecule biosynthesis|negative regulation of cellular macromolecule formation							tb	2010-09-15T08:55:48Z					biological_process											owl:Class	
GO:0036028	biolink:NamedThing	protein C inhibitor-thrombin complex	A heterodimeric protein complex that contains protein C inhibitor (SERPINA5) and thrombin (F2); formation of the complex inhibits the serine protease activity of thrombin.	tmpzr1t_l9r_go_relaxed.owl	SERPINA5-thrombin complex|PCI-thrombin complex|plasma serine protease inhibitor-thrombin complex|protein C inhibitor-F2 complex|serpin A5-thrombin complex|protein C inhibitor-coagulation factor II complex							bf	2011-10-19T01:40:18Z					cellular_component											owl:Class	
GO:0018602	biolink:NamedThing	2,4-dichlorophenoxyacetate alpha-ketoglutarate dioxygenase activity	Catalysis of the reaction: 2,4-dichlorophenoxyacetate + 2-oxoglutarate + oxygen = 2,4-dichlorophenol + glyoxylate + succinate + CO2.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0274|RHEA:48984|MetaCyc:RXN-9863									molecular_function											owl:Class	
GO:0045623	biolink:NamedThing	negative regulation of T-helper cell differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of T-helper cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	inhibition of T-helper cell differentiation|down regulation of T-helper cell differentiation|downregulation of T-helper cell differentiation|down-regulation of T-helper cell differentiation|negative regulation of T-helper cell development					Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.								biological_process											owl:Class	
GO:0034439	biolink:NamedThing	lipoprotein lipid oxidation	The modification of a lipoprotein by oxidation of the lipid group.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0010795	biolink:NamedThing	regulation of ubiquinone biosynthetic process	Any process that modulates the frequency, rate or extent of ubiquinone biosynthesis. Ubiquinone biosynthesis consists of the chemical reactions and pathways resulting in the formation of ubiquinone, a lipid-soluble electron-transporting coenzyme.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1901801	biolink:NamedThing	1,5-anhydro-D-fructose metabolic process	The chemical reactions and pathways involving 1,5-anhydro-D-fructose.	tmpzr1t_l9r_go_relaxed.owl	1,5-anhydro-D-fructose metabolism							yaf	2013-01-22T09:56:20Z					biological_process											owl:Class	
GO:0015956	biolink:NamedThing	bis(5'-nucleosidyl) oligophosphate metabolic process	The chemical reactions and pathways involving a bis(5'-nucleosidyl) oligophosphate, a compound formed of two nucleosides joined together through their 5' carbons by a chain of phosphate molecules.	tmpzr1t_l9r_go_relaxed.owl	bis(5'-nucleosidyl) oligophosphate metabolism													biological_process											owl:Class	
GO:0048765	biolink:NamedThing	root hair cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a root hair cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0010053	biolink:NamedThing	root epidermal cell differentiation	The process in which a relatively unspecialized cell in the root epidermis acquires the specialized features of a trichoblast or atrichoblast.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0060298	biolink:NamedThing	positive regulation of sarcomere organization	Any process that increases the rate, frequency or extent of myofibril assembly by organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of sarcomere organisation													biological_process											owl:Class	
GO:0004123	biolink:NamedThing	cystathionine gamma-lyase activity	Catalysis of the reaction: L-cystathionine + H2O = 2-oxobutanoate + L-cysteine + NH4+.	tmpzr1t_l9r_go_relaxed.owl	homoserine dehydratase activity|gamma-cystathionase activity|homoserine deaminase activity|L-cystathionine cysteine-lyase (deaminating)|homoserine deaminase-cystathionase activity|L-cystathionine cysteine-lyase (deaminating; 2-oxobutanoate-forming)				KEGG_REACTION:R01001|MetaCyc:CYSTAGLY-RXN|EC:4.4.1.1|Reactome:R-HSA-1614583|RHEA:14005							GO:0016225		molecular_function											owl:Class	
GO:0061833	biolink:NamedThing	protein localization to tricellular tight junction	A process in which a protein is transported to, or maintained in, a location within a tricellular tight junction.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0150105	biolink:NamedThing	protein localization to cell-cell junction	A process in which a protein is transported to, or maintained, in a location within a cell-cell junction.	tmpzr1t_l9r_go_relaxed.owl								bc	2019-06-11T11:00:18Z					biological_process											owl:Class	
GO:0039620	biolink:NamedThing	T=7 icosahedral viral capsid	The protein coat that surrounds the infective nucleic acid in some virus particles where the subunits (capsomeres) are arranged to form an icosahedron with T=7 symmetry. The T=7 capsid is composed of 12 pentameric and 60 hexameric capsomeres.	tmpzr1t_l9r_go_relaxed.owl					VZ:804	Spherical viruses with T numbers greater than or equal to 7 are skewed. They are therefore described as either right-handed (dextro) or left-handed (laevo).		bf	2012-07-18T02:16:40Z					cellular_component											owl:Class	
GO:0099031	biolink:NamedThing	anchored component of postsynaptic density membrane	The component of the postsynaptic density membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0099030	biolink:NamedThing	anchored component of postsynaptic specialization membrane	The component of the postsynaptic specialization membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0050796	biolink:NamedThing	regulation of insulin secretion	Any process that modulates the frequency, rate or extent of the regulated release of insulin.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0140439	biolink:NamedThing	protein-cysteine S-stearoyltransferase activity	Catalysis of the transfer of a stearoyl (systematic name, octadecanoyl) group to a sulfur atom on the cysteine of a protein molecule, in the reaction: octadecanoyl-CoA + L-cysteinyl-[protein] = CoA + S-octadecanoyl-L-cysteinyl-[protein].	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/18882			RHEA:59740			pg	2020-03-11T09:55:48Z					molecular_function											owl:Class	
GO:0019707	biolink:NamedThing	protein-cysteine S-acyltransferase activity	Catalysis of the transfer of an acyl group to a sulfur atom on the cysteine of a protein molecule.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/18882			RHEA:63372									molecular_function											owl:Class	
GO:0034410	biolink:NamedThing	cell wall beta-glucan biosynthetic process	The chemical reactions and pathways resulting in the formation of beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds, found in the walls of cells.	tmpzr1t_l9r_go_relaxed.owl	cell wall beta-glucan biosynthesis|cell wall beta-glucan anabolism|cell wall beta-glucan synthesis|cell wall beta-glucan formation													biological_process											owl:Class	
GO:0002330	biolink:NamedThing	pre-B cell receptor expression	The process leading up to expression of the pre-B cell receptor on the surface of pre-B cells, starting with the recombination of an immunuglobulin heavy chain locus, including expression of the surrogate light chain, the  association of the surrogate light chain with the heavy chain, and expression of the complete pre-B cell receptor on the cell surface. pre-B cell receptor expression is a key checkpoint in the transition of pro-B cell to pre-B cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0021617	biolink:NamedThing	glossopharyngeal nerve structural organization	The process that contributes to the act of creating the structural organization of the glossopharyngeal nerve. This process pertains to the physical shaping of a rudimentary structure. Various sensory and motor branches of the glossopharyngeal nerve supply nerve connections to the pharynx and back of the tongue. The branchial motor component contains motor fibers that innervate muscles that elevate the pharynx and larynx, and the tympanic branch supplies parasympathetic fibers to the otic ganglion.	tmpzr1t_l9r_go_relaxed.owl	CN IX structural organization|glossopharyngeal nerve structural organisation													biological_process											owl:Class	
GO:0021604	biolink:NamedThing	cranial nerve structural organization	The process that contributes to the act of creating the structural organization of the cranial nerves. This process pertains to the physical shaping of a rudimentary structure. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions.	tmpzr1t_l9r_go_relaxed.owl	cranial nerve structural organisation													biological_process											owl:Class	
GO:0062002	biolink:NamedThing	regulation of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity	Any process that modulates the frequency or rate of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity.	tmpzr1t_l9r_go_relaxed.owl								dph	2018-02-26T13:16:39Z					biological_process											owl:Class	
GO:0050799	biolink:NamedThing	cocaine biosynthetic process	The chemical reactions and pathways resulting in the formation of cocaine, an alkaloid obtained from the dried leaves of the shrub Erythroxylon coca. It is a cerebral stimulant and narcotic.	tmpzr1t_l9r_go_relaxed.owl	cocaine anabolism|cocaine formation|cocaine synthesis|cocaine biosynthesis													biological_process											owl:Class	
GO:1903979	biolink:NamedThing	negative regulation of microglial cell activation	Any process that stops, prevents or reduces the frequency, rate or extent of microglial cell activation.	tmpzr1t_l9r_go_relaxed.owl	inhibition of microglial cell activation|down regulation of microglial cell activation|downregulation of microglial cell activation|down-regulation of microglial cell activation							nc	2015-03-02T15:17:39Z					biological_process											owl:Class	
GO:1900508	biolink:NamedThing	positive regulation of iron-sulfur-molybdenum cofactor assembly	Any process that activates or increases the frequency, rate or extent of iron-sulfur-molybdenum cofactor assembly.	tmpzr1t_l9r_go_relaxed.owl	up regulation of iron molybdenum cofactor biosynthesis|positive regulation of iron molybdenum cofactor biosynthetic process|activation of iron-sulfur-molybdenum cofactor assembly|positive regulation of iron molybdenum cofactor assembly|activation of FeMoco assembly|up-regulation of iron molybdenum cofactor biosynthetic process|up regulation of iron molybdenum cofactor assembly|positive regulation of FeMoco assembly|up-regulation of FeMoco biosynthetic process|activation of iron molybdenum cofactor biosynthetic process|up-regulation of iron molybdenum cofactor biosynthesis|upregulation of FeMoco biosynthetic process|positive regulation of iron molybdenum cofactor biosynthesis|upregulation of iron molybdenum cofactor assembly|up-regulation of iron-sulfur-molybdenum cofactor assembly|up-regulation of iron molybdenum cofactor assembly|up regulation of FeMoco biosynthetic process|activation of FeMoco biosynthetic process|up regulation of iron molybdenum cofactor biosynthetic process|upregulation of iron molybdenum cofactor biosynthesis|upregulation of iron molybdenum cofactor biosynthetic process|activation of iron molybdenum cofactor assembly|activation of iron molybdenum cofactor biosynthesis|upregulation of FeMoco assembly|up-regulation of FeMoco assembly|up regulation of iron-sulfur-molybdenum cofactor assembly|up regulation of FeMoco assembly|positive regulation of FeMoco biosynthetic process|upregulation of iron-sulfur-molybdenum cofactor assembly							tt	2012-05-02T04:02:37Z					biological_process											owl:Class	
GO:0035715	biolink:NamedThing	chemokine (C-C motif) ligand 2 binding	Binding to chemokine (C-C motif) ligand 2.	tmpzr1t_l9r_go_relaxed.owl	CCL2 binding							bf	2011-03-03T04:24:24Z					molecular_function											owl:Class	
GO:0019957	biolink:NamedThing	C-C chemokine binding	Binding to a C-C chemokine; C-C chemokines do not have an amino acid between the first two cysteines of the characteristic four-cysteine motif.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0048511	biolink:NamedThing	rhythmic process	Any process pertinent to the generation and maintenance of rhythms in the physiology of an organism.	tmpzr1t_l9r_go_relaxed.owl	rhythm													biological_process											owl:Class	
GO:0080122	biolink:NamedThing	AMP transmembrane transporter activity	Enables the transfer of AMP, adenosine monophosphate, from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	adenosine monophosphate transmembrane transporter activity							dhl	2009-04-28T04:05:39Z					molecular_function											owl:Class	
GO:0010882	biolink:NamedThing	regulation of cardiac muscle contraction by calcium ion signaling	Any process that modulates the frequency, rate or extent of cardiac muscle contraction by changing the calcium ion signals that trigger contraction.	tmpzr1t_l9r_go_relaxed.owl	regulation of cardiac muscle contraction by calcium ion signalling													biological_process											owl:Class	
GO:0032646	biolink:NamedThing	regulation of hepatocyte growth factor production	Any process that modulates the frequency, rate, or extent of hepatocyte growth factor production.	tmpzr1t_l9r_go_relaxed.owl	regulation of scatter factor production|regulation of hepatocyte growth factor biosynthetic process|regulation of HGF production											GO:0048176		biological_process											owl:Class	
GO:0070724	biolink:NamedThing	BMP receptor complex	A protein complex that acts as a receptor for bone morphogenetic proteins (BMPs); a homo- or heterodimer of type I and/or type II BMP receptor subunits.	tmpzr1t_l9r_go_relaxed.owl	bone morphogenetic protein receptor complex							mah	2009-06-15T02:34:27Z					cellular_component											owl:Class	
GO:0098802	biolink:NamedThing	plasma membrane signaling receptor complex	Any protein complex that is part of the plasma membrane and which functions as a signaling receptor.	tmpzr1t_l9r_go_relaxed.owl						Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.								cellular_component											owl:Class	
GO:0052609	biolink:NamedThing	4-ketotorulene 3-hydroxylase activity	Catalysis of the reaction: 4-ketotorulene + a reduced electron acceptor + oxygen = 3-hydroxy-4-ketotorulene + an oxidized electron acceptor + H2O.	tmpzr1t_l9r_go_relaxed.owl	carotene beta-ring hydroxylase activity|beta-ring carotenoid 3-hydroxylase activity|beta-carotene hydroxylase activity				MetaCyc:RXN-8218									molecular_function											owl:Class	
GO:0009047	biolink:NamedThing	dosage compensation by hyperactivation of X chromosome	Compensating for the two-fold variation in X-chromosome:autosome ratios between sexes by a global hyperactivation of all, or most of, the genes on the X-chromosome in the heterogametic sex, leading to a two-fold increase in gene expression from this chromosome. An example of this is found in Drosophila melanogaster.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:2001213	biolink:NamedThing	negative regulation of vasculogenesis	Any process that stops, prevents or reduces the frequency, rate or extent of vasculogenesis.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of vascular morphogenesis							yaf	2011-11-15T01:22:36Z					biological_process											owl:Class	
GO:0003398	biolink:NamedThing	glial cell differentiation involved in amphid sensory organ development	The process in which a relatively unspecialized cell acquires the specialized features of a glial cell of the amphid sensory organ.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-12-09T09:55:27Z					biological_process											owl:Class	
GO:0010001	biolink:NamedThing	glial cell differentiation	The process in which a relatively unspecialized cell acquires the specialized features of a glial cell.	tmpzr1t_l9r_go_relaxed.owl	neuroglia differentiation|glia cell differentiation											GO:0007404|GO:0043360		biological_process											owl:Class	
GO:0015940	biolink:NamedThing	pantothenate biosynthetic process	The chemical reactions and pathways resulting in the formation of pantothenate, the anion of pantothenic acid. It is a B complex vitamin that is a constituent of coenzyme A and is distributed ubiquitously in foods.	tmpzr1t_l9r_go_relaxed.owl	pantothenate anabolism|pantothenate anabolism from valine|pantothenate formation from 2-oxypantoyl lactone|pantothenate synthesis|pantothenate synthesis from valine|pantothenate synthesis from 2-oxypantoyl lactone|pantothenate biosynthetic process from valine|pantothenate anabolism from 2-oxypantoyl lactone|vitamin B5 biosynthesis|pantothenate formation|pantothenate biosynthetic process from 2-dehydropantolactone|pantothenate biosynthetic process from 2-oxypantoyl lactone|pantothenate formation from valine|pantothenate biosynthesis from 2-oxypantoyl lactone|vitamin B5 biosynthetic process|pantothenate biosynthesis|pantothenate biosynthesis from valine				MetaCyc:PANTO-PWY|MetaCyc:PANTOSYN-PWY|MetaCyc:PWY-3961|MetaCyc:PWY-4221							GO:0033317|GO:0033318		biological_process											owl:Class	
GO:0015939	biolink:NamedThing	pantothenate metabolic process	The chemical reactions and pathways involving pantothenate, the anion of pantothenic acid, the amide of beta-alanine and pantoic acid. It is a B complex vitamin that is a constituent of coenzyme A and is distributed ubiquitously in foods.	tmpzr1t_l9r_go_relaxed.owl	vitamin B5 metabolism|pantothenate metabolism|vitamin B5 metabolic process											GO:0006770		biological_process											owl:Class	
GO:0050539	biolink:NamedThing	maleimide hydrolase activity	Catalysis of the reaction: H(2)O + maleimide = H(+) + maleamate.	tmpzr1t_l9r_go_relaxed.owl	imidase activity|cyclic-imide amidohydrolase (decyclicizing)|cyclic imide hydrolase activity|cyclic-imide amidohydrolase (decyclizing)				MetaCyc:3.5.2.16-RXN|EC:3.5.2.16|KEGG_REACTION:R05781|RHEA:24476									molecular_function											owl:Class	
GO:0080110	biolink:NamedThing	sporopollenin biosynthetic process	The chemical reactions and pathways resulting in the formation of sporopollenin, a primary constituent of the pollen exine layer.	tmpzr1t_l9r_go_relaxed.owl	sporopollenin biosynthesis							dhl	2009-04-23T04:44:16Z					biological_process											owl:Class	
GO:0034220	biolink:NamedThing	ion transmembrane transport	A process in which an ion is transported across a membrane.	tmpzr1t_l9r_go_relaxed.owl	ion membrane transport|transmembrane ion transport|ATP hydrolysis coupled ion transmembrane transport					Note that this term is not intended for use in annotating lateral movement within membranes.						GO:0099131		biological_process											owl:Class	
GO:1901159	biolink:NamedThing	xylulose 5-phosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of xylulose 5-phosphate.	tmpzr1t_l9r_go_relaxed.owl	xylulose 5-phosphate formation|xylulose 5-phosphate synthesis|xylulose 5-phosphate anabolism|xylulose 5-phosphate biosynthesis							bf	2012-07-18T04:42:24Z					biological_process											owl:Class	
GO:0035821	biolink:NamedThing	modulation of process of other organism	The process in which an organism effects a change in the structure or processes of another organism.	tmpzr1t_l9r_go_relaxed.owl	regulation of morphology of other organism|regulation of physiological process of other organism|modification of morphology or physiology of other organism|regulation of physiology of other organism|regulation of morphology or physiology of other organism	https://github.com/geneontology/go-ontology/issues/18605						bf	2011-04-21T01:31:51Z					biological_process											owl:Class	
GO:0003013	biolink:NamedThing	circulatory system process	A organ system process carried out by any of the organs or tissues of the circulatory system. The circulatory system is an organ system that moves extracellular fluids to and from tissue within a multicellular organism.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Circulatory_system									biological_process											owl:Class	
GO:0003008	biolink:NamedThing	system process	A multicellular organismal process carried out by any of the organs or tissues in an organ system. An organ system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a biological objective.	tmpzr1t_l9r_go_relaxed.owl	organ system process													biological_process											owl:Class	
GO:1904224	biolink:NamedThing	negative regulation of glucuronosyltransferase activity	Any process that stops, prevents or reduces the frequency, rate or extent of glucuronosyltransferase activity.	tmpzr1t_l9r_go_relaxed.owl	downregulation of UDP-glucuronosyltransferase activity|negative regulation of p-nitrophenylglucuronosyltransferase activity|inhibition of UDP-glucuronate-4-hydroxybiphenyl glucuronosyltransferase activity|down regulation of 1-naphthol-UDP-glucuronosyltransferase activity|inhibition of UDP glucuronic acid transferase activity|down regulation of bilirubin UDPGT activity|down-regulation of UDPGT activity|downregulation of UDPGT activity|negative regulation of bilirubin UDP-glucuronosyltransferase activity|negative regulation of bilirubin UDPGT activity|down-regulation of uridine diphosphoglucuronosyltransferase activity|inhibition of 4-hydroxybiphenyl UDP-glucuronosyltransferase activity|inhibition of UDP glucuronosyltransferase activity|inhibition of UDP glucuronate-estriol glucuronosyltransferase activity|inhibition of p-hydroxybiphenyl UDP glucuronyltransferase activity|down-regulation of uridine diphosphoglucuronate-bilirubin glucuronosyltransferase activity|downregulation of 4-methylumbelliferone UDP-glucuronosyltransferase activity|down-regulation of glucuronosyltransferase activity|down regulation of bilirubin monoglucuronide glucuronyltransferase activity|negative regulation of p-nitrophenol UDP-glucuronosyltransferase activity|downregulation of 3alpha-hydroxysteroid UDP-glucuronosyltransferase activity|inhibition of UDPglucuronate beta-D-glucuronosyltransferase (acceptor-unspecific) activity|down regulation of UDPGA-glucuronyltransferase activity|down-regulation of bilirubin glucuronyltransferase activity|downregulation of p-nitrophenylglucuronosyltransferase activity|inhibition of 4-nitrophenol UDP-glucuronyltransferase activity|inhibition of estrone UDPglucuronosyltransferase activity|inhibition of UDP glucuronyltransferase activity|inhibition of uridine 5'-diphosphoglucuronyltransferase activity|negative regulation of bilirubin uridine diphosphoglucuronyltransferase activity|negative regulation of UDP glucuronate-estriol glucuronosyltransferase activity|negative regulation of 3alpha-hydroxysteroid UDP-glucuronosyltransferase activity|downregulation of uridine diphosphoglucuronate-4-hydroxybiphenyl glucuronosyltransferase activity|down-regulation of bilirubin UDPGT activity|negative regulation of p-nitrophenol UDP-glucuronyltransferase activity|negative regulation of uridine diphosphoglucuronyltransferase activity|down-regulation of UDP-glucuronosyltransferase activity|down-regulation of uridine diphosphoglucuronate-estriol glucuronosyltransferase activity|down-regulation of 17beta-hydroxysteroid UDP-glucuronosyltransferase activity|downregulation of estriol UDPglucuronosyltransferase activity|downregulation of UDP glucuronosyltransferase activity|negative regulation of bilirubin glucuronyltransferase activity|down-regulation of 3alpha-hydroxysteroid UDP-glucuronosyltransferase activity|inhibition of morphine glucuronyltransferase activity|down regulation of UDP glucuronosyltransferase activity|negative regulation of UDP glucuronyltransferase activity|inhibition of uridine diphosphoglucuronate-estriol 16-alpha-glucuronosyltransferase activity|inhibition of bilirubin glucuronyltransferase activity|inhibition of PNP-UDPGT|downregulation of UDP-glucuronyltransferase activity|negative regulation of p-hydroxybiphenyl UDP glucuronyltransferase activity|down-regulation of p-phenylphenol glucuronyltransferase activity|downregulation of UDP glucuronate-estradiol-glucuronosyltransferase activity|inhibition of 1-naphthol glucuronyltransferase activity|downregulation of uridine diphosphoglucuronate-bilirubin glucuronoside glucuronosyltransferase activity|down-regulation of p-nitrophenol UDP-glucuronosyltransferase activity|negative regulation of p-phenylphenol glucuronyltransferase activity|downregulation of bilirubin UDPGT activity|negative regulation of uridine diphosphoglucuronate-estriol 16alpha-glucuronosyltransferase activity|down regulation of p-nitrophenol UDP-glucuronosyltransferase activity|down regulation of UDPglucuronate beta-D-glucuronosyltransferase (acceptor-unspecific) activity|inhibition of uridine diphosphoglucuronyltransferase activity|downregulation of UDPGA transferase activity|down regulation of phenyl-UDP-glucuronosyltransferase activity|downregulation of uridine diphosphoglucuronyltransferase activity|down-regulation of UDP-glucuronate-bilirubin glucuronyltransferase activity|negative regulation of UDPGA-glucuronyltransferase activity|inhibition of phenyl-UDP-glucuronosyltransferase activity|negative regulation of bilirubin monoglucuronide glucuronyltransferase activity|down-regulation of 4-nitrophenol UDP-glucuronyltransferase activity|downregulation of morphine glucuronyltransferase activity|down-regulation of UDP glucuronosyltransferase activity|inhibition of bilirubin monoglucuronide glucuronyltransferase activity|down regulation of UDP-glucuronosyltransferase activity|negative regulation of UDP glucuronate-estradiol-glucuronosyltransferase activity|negative regulation of 4-hydroxybiphenyl UDP-glucuronosyltransferase activity|down-regulation of phenyl-UDP-glucuronosyltransferase activity|negative regulation of 17beta-hydroxysteroid UDP-glucuronosyltransferase activity|down regulation of uridine diphosphoglucuronate-estradiol glucuronosyltransferase activity|negative regulation of ciramadol UDP-glucuronyltransferase activity|inhibition of uridine diphosphoglucuronate-4-hydroxybiphenyl glucuronosyltransferase activity|down regulation of UDPGA transferase activity|inhibition of uridine diphosphoglucuronate-estradiol glucuronosyltransferase activity|inhibition of 17-OH steroid UDPGT activity|down regulation of UDP-glucuronate-4-hydroxybiphenyl glucuronosyltransferase activity|inhibition of UDP-glucuronate beta-D-glucuronosyltransferase (acceptor-unspecific)|inhibition of uridine diphosphoglucuronate-bilirubin glucuronoside glucuronosyltransferase activity|down-regulation of bilirubin uridine diphosphoglucuronyltransferase activity|down regulation of bilirubin UDP-glucuronosyltransferase activity|inhibition of bilirubin uridine diphosphoglucuronyltransferase activity|negative regulation of PNP-UDPGT|inhibition of uridine diphosphoglucuronate-estriol glucuronosyltransferase activity|downregulation of 1-naphthol glucuronyltransferase activity|down regulation of uridine diphosphoglucuronate-bilirubin glucuronosyltransferase activity|down regulation of estrone UDPglucuronosyltransferase activity|down-regulation of 3-alpha-hydroxysteroid UDP-glucuronosyltransferase activity|down regulation of estriol UDPglucuronosyltransferase activity|downregulation of 4-nitrophenol UDP-glucuronyltransferase activity|downregulation of 1-naphthol-UDP-glucuronosyltransferase activity|down regulation of p-nitrophenylglucuronosyltransferase activity|downregulation of bilirubin monoglucuronide glucuronyltransferase activity|downregulation of phenyl-UDP-glucuronosyltransferase activity|inhibition of estriol UDPglucuronosyltransferase activity|down regulation of bilirubin uridine diphosphoglucuronyltransferase activity|down regulation of uridine diphosphoglucuronate-bilirubin glucuronoside glucuronosyltransferase activity|negative regulation of 4-methylumbelliferone UDP-glucuronosyltransferase activity|inhibition of UDP-glucuronyltransferase activity|downregulation of UDP-glucuronate-bilirubin glucuronyltransferase activity|inhibition of 17-beta-hydroxysteroid UDP-glucuronosyltransferase activity|inhibition of 4-methylumbelliferone UDP-glucuronosyltransferase activity|down regulation of 17-OH steroid UDPGT activity|downregulation of glucuronosyltransferase activity|negative regulation of phenyl-UDP-glucuronosyltransferase activity|downregulation of uridine diphosphoglucuronosyltransferase activity|negative regulation of 4-nitrophenol UDPGT activity|inhibition of uridine diphosphoglucuronate-1,2-diacylglycerol glucuronosyltransferase activity|downregulation of p-phenylphenol glucuronyltransferase activity|down regulation of pnp-UDPGT activity|down regulation of uridine diphosphoglucuronate-estriol glucuronosyltransferase activity|down-regulation of uridine diphosphoglucuronate-bilirubin glucuronoside glucuronosyltransferase activity|down-regulation of uridine diphosphoglucuronate-estriol 16alpha-glucuronosyltransferase activity|negative regulation of uridine diphosphoglucuronate-1,2-diacylglycerol glucuronosyltransferase activity|downregulation of UDPglucuronate beta-D-glucuronosyltransferase (acceptor-unspecific) activity|down-regulation of 1-naphthol-UDP-glucuronosyltransferase activity|down-regulation of uridine diphosphoglucuronate-4-hydroxybiphenyl glucuronosyltransferase activity|inhibition of p-nitrophenol UDP-glucuronosyltransferase activity|inhibition of p-nitrophenol UDP-glucuronyltransferase activity|inhibition of p-nitrophenylglucuronosyltransferase activity|negative regulation of UDP-glucuronyltransferase activity|downregulation of ciramadol UDP-glucuronyltransferase activity|negative regulation of 1-naphthol-UDP-glucuronosyltransferase activity|down regulation of 4-nitrophenol UDPGT activity|negative regulation of UDPGT activity|down regulation of 4-hydroxybiphenyl UDP-glucuronosyltransferase activity|down-regulation of bilirubin monoglucuronide glucuronyltransferase activity|down regulation of 3-alpha-hydroxysteroid UDP-glucuronosyltransferase activity|inhibition of p-phenylphenol glucuronyltransferase activity|down regulation of UDP glucuronyltransferase activity|down regulation of uridine diphosphoglucuronate-1,2-diacylglycerol glucuronosyltransferase activity|down-regulation of uridine 5'-diphosphoglucuronyltransferase activity|downregulation of 17-OH steroid UDPGT activity|down regulation of bilirubin glucuronyltransferase activity|negative regulation of uridine diphosphoglucuronate-4-hydroxybiphenyl glucuronosyltransferase activity|down-regulation of morphine glucuronyltransferase activity|down regulation of GT activity|downregulation of p-hydroxybiphenyl UDP glucuronyltransferase activity|down regulation of 4-nitrophenol UDP-glucuronyltransferase activity|inhibition of 4-nitrophenol UDPGT activity|down regulation of UDPGT activity|negative regulation of UDP-glucuronate-bilirubin glucuronyltransferase activity|down-regulation of pnp-UDPGT activity|down-regulation of uridine diphosphoglucuronate-estradiol glucuronosyltransferase activity|inhibition of 3alpha-hydroxysteroid UDP-glucuronosyltransferase activity|downregulation of GT activity|downregulation of uridine diphosphoglucuronate-estriol 16alpha-glucuronosyltransferase activity|down regulation of 17beta-hydroxysteroid UDP-glucuronosyltransferase activity|downregulation of bilirubin uridine diphosphoglucuronyltransferase activity|downregulation of 17-beta-hydroxysteroid UDP-glucuronosyltransferase activity|downregulation of uridine diphosphoglucuronate-1,2-diacylglycerol glucuronosyltransferase activity|downregulation of p-nitrophenol UDP-glucuronyltransferase activity|down-regulation of p-hydroxybiphenyl UDP glucuronyltransferase activity|down regulation of morphine glucuronyltransferase activity|down regulation of glucuronosyltransferase activity|downregulation of uridine diphosphoglucuronate-estradiol glucuronosyltransferase activity|down regulation of PNP-UDPGT|downregulation of UDP glucuronyltransferase activity|down-regulation of 4-nitrophenol UDPGT activity|inhibition of 17beta-hydroxysteroid UDP-glucuronosyltransferase activity|down-regulation of UDP-glucuronyltransferase activity|downregulation of UDPGA-glucuronyltransferase activity|downregulation of bilirubin UDP-glucuronosyltransferase activity|inhibition of UDP-glucuronate-bilirubin glucuronyltransferase activity|downregulation of UDP-glucuronate-4-hydroxybiphenyl glucuronosyltransferase activity|downregulation of p-nitrophenol UDP-glucuronosyltransferase activity|down-regulation of UDP glucuronate-estriol glucuronosyltransferase activity|negative regulation of UDP-glucuronosyltransferase activity|downregulation of uridine diphosphoglucuronate-estriol 16-alpha-glucuronosyltransferase activity|downregulation of pnp-UDPGT activity|downregulation of UDP glucuronic acid transferase activity|inhibition of uridine diphosphoglucuronosyltransferase activity|negative regulation of uridine 5'-diphosphoglucuronyltransferase activity|inhibition of 1-naphthol-UDP-glucuronosyltransferase activity|negative regulation of morphine glucuronyltransferase activity|down regulation of uridine diphosphoglucuronate-estriol 16alpha-glucuronosyltransferase activity|down-regulation of bilirubin UDP-glucuronosyltransferase activity|down-regulation of UDPglucuronate beta-D-glucuronosyltransferase (acceptor-unspecific) activity|negative regulation of UDP-glucuronate beta-D-glucuronosyltransferase (acceptor-unspecific)|down regulation of 1-naphthol glucuronyltransferase activity|down regulation of 4-methylumbelliferone UDP-glucuronosyltransferase activity|negative regulation of pnp-UDPGT activity|inhibition of uridine diphosphoglucuronate-estriol 16alpha-glucuronosyltransferase activity|inhibition of UDPGT activity|downregulation of 4-hydroxybiphenyl UDP-glucuronosyltransferase activity|downregulation of bilirubin glucuronyltransferase activity|downregulation of UDP glucuronate-estriol glucuronosyltransferase activity|down regulation of uridine diphosphoglucuronate-estriol 16-alpha-glucuronosyltransferase activity|inhibition of uridine diphosphoglucuronate-bilirubin glucuronosyltransferase activity|negative regulation of 1-naphthol glucuronyltransferase activity|negative regulation of uridine diphosphoglucuronosyltransferase activity|down-regulation of 4-methylumbelliferone UDP-glucuronosyltransferase activity|down regulation of uridine diphosphoglucuronate-4-hydroxybiphenyl glucuronosyltransferase activity|down-regulation of UDP glucuronate-estradiol-glucuronosyltransferase activity|negative regulation of uridine diphosphoglucuronate-estradiol glucuronosyltransferase activity|downregulation of uridine diphosphate glucuronyltransferase activity|downregulation of uridine 5'-diphosphoglucuronyltransferase activity|inhibition of uridine diphosphate glucuronyltransferase activity|inhibition of UDP glucuronate-estradiol-glucuronosyltransferase activity|negative regulation of uridine diphosphoglucuronate-bilirubin glucuronoside glucuronosyltransferase activity|down regulation of p-hydroxybiphenyl UDP glucuronyltransferase activity|down regulation of p-nitrophenol UDP-glucuronyltransferase activity|negative regulation of estriol UDPglucuronosyltransferase activity|down regulation of uridine diphosphoglucuronyltransferase activity|down regulation of uridine 5'-diphosphoglucuronyltransferase activity|down-regulation of UDPGA-glucuronyltransferase activity|down regulation of UDP glucuronic acid transferase activity|inhibition of UDP-glucuronosyltransferase activity|down-regulation of 4-hydroxybiphenyl UDP-glucuronosyltransferase activity|downregulation of uridine diphosphoglucuronate-estriol glucuronosyltransferase activity|down regulation of p-phenylphenol glucuronyltransferase activity|negative regulation of GT activity|downregulation of uridine diphosphoglucuronate-bilirubin glucuronosyltransferase activity|downregulation of 3-alpha-hydroxysteroid UDP-glucuronosyltransferase activity|down-regulation of p-nitrophenylglucuronosyltransferase activity|down-regulation of 3-OH androgenic UDPGT activity|negative regulation of uridine diphosphoglucuronate-bilirubin glucuronosyltransferase activity|down-regulation of uridine diphosphate glucuronyltransferase activity|down-regulation of estrone UDPglucuronosyltransferase activity|down-regulation of ciramadol UDP-glucuronyltransferase activity|down regulation of UDP glucuronate-estriol glucuronosyltransferase activity|down-regulation of p-nitrophenol UDP-glucuronyltransferase activity|inhibition of ciramadol UDP-glucuronyltransferase activity|negative regulation of UDPglucuronate beta-D-glucuronosyltransferase (acceptor-unspecific) activity|inhibition of glucuronosyltransferase activity|downregulation of PNP-UDPGT|inhibition of bilirubin UDP-glucuronosyltransferase activity|negative regulation of 3-OH androgenic UDPGT activity|inhibition of UDPGA transferase activity|down regulation of UDP-glucuronate-bilirubin glucuronyltransferase activity|negative regulation of estrone UDPglucuronosyltransferase activity|downregulation of UDP-glucuronate beta-D-glucuronosyltransferase (acceptor-unspecific)|down-regulation of estriol UDPglucuronosyltransferase activity|down-regulation of UDP-glucuronate beta-D-glucuronosyltransferase (acceptor-unspecific)|down-regulation of uridine diphosphoglucuronyltransferase activity|negative regulation of UDP glucuronic acid transferase activity|negative regulation of UDPGA transferase activity|negative regulation of uridine diphosphoglucuronate-estriol 16-alpha-glucuronosyltransferase activity|down-regulation of PNP-UDPGT|down-regulation of uridine diphosphoglucuronate-estriol 16-alpha-glucuronosyltransferase activity|down regulation of UDP glucuronate-estradiol-glucuronosyltransferase activity|downregulation of 3-OH androgenic UDPGT activity|down-regulation of 17-OH steroid UDPGT activity|down regulation of 3-OH androgenic UDPGT activity|inhibition of pnp-UDPGT activity|down-regulation of UDP glucuronyltransferase activity|inhibition of 3-OH androgenic UDPGT activity|negative regulation of 17-OH steroid UDPGT activity|inhibition of bilirubin UDPGT activity|downregulation of estrone UDPglucuronosyltransferase activity|negative regulation of uridine diphosphoglucuronate-estriol glucuronosyltransferase activity|inhibition of GT activity|down-regulation of GT activity|negative regulation of 3-alpha-hydroxysteroid UDP-glucuronosyltransferase activity|down regulation of 17-beta-hydroxysteroid UDP-glucuronosyltransferase activity|down-regulation of 17-beta-hydroxysteroid UDP-glucuronosyltransferase activity|down regulation of ciramadol UDP-glucuronyltransferase activity|down regulation of uridine diphosphoglucuronosyltransferase activity|down-regulation of 1-naphthol glucuronyltransferase activity|down-regulation of UDPGA transferase activity|negative regulation of UDP-glucuronate-4-hydroxybiphenyl glucuronosyltransferase activity|negative regulation of 4-nitrophenol UDP-glucuronyltransferase activity|inhibition of UDPGA-glucuronyltransferase activity|negative regulation of 17-beta-hydroxysteroid UDP-glucuronosyltransferase activity|downregulation of 17beta-hydroxysteroid UDP-glucuronosyltransferase activity|downregulation of 4-nitrophenol UDPGT activity|down-regulation of UDP-glucuronate-4-hydroxybiphenyl glucuronosyltransferase activity|inhibition of 3-alpha-hydroxysteroid UDP-glucuronosyltransferase activity|negative regulation of uridine diphosphate glucuronyltransferase activity|down regulation of UDP-glucuronate beta-D-glucuronosyltransferase (acceptor-unspecific)|down regulation of UDP-glucuronyltransferase activity|down regulation of 3alpha-hydroxysteroid UDP-glucuronosyltransferase activity|down-regulation of UDP glucuronic acid transferase activity|down-regulation of uridine diphosphoglucuronate-1,2-diacylglycerol glucuronosyltransferase activity|down regulation of uridine diphosphate glucuronyltransferase activity|negative regulation of UDP glucuronosyltransferase activity					i2 UDP-glucuronosyltransferase splice species alter glucuronidation activity of i1 UDP-glucuronosyltransferase splice species		rl	2015-05-15T08:44:26Z					biological_process											owl:Class	
GO:1904223	biolink:NamedThing	regulation of glucuronosyltransferase activity	Any process that modulates the frequency, rate or extent of glucuronosyltransferase activity.	tmpzr1t_l9r_go_relaxed.owl	regulation of 17-OH steroid UDPGT activity|regulation of p-phenylphenol glucuronyltransferase activity|regulation of 4-nitrophenol UDP-glucuronyltransferase activity|regulation of UDP-glucuronate beta-D-glucuronosyltransferase (acceptor-unspecific)|regulation of 17-beta-hydroxysteroid UDP-glucuronosyltransferase activity|regulation of UDPGA-glucuronyltransferase activity|regulation of uridine diphosphoglucuronyltransferase activity|regulation of uridine diphosphoglucuronate-estriol 16alpha-glucuronosyltransferase activity|regulation of UDPGA transferase activity|regulation of 3alpha-hydroxysteroid UDP-glucuronosyltransferase activity|regulation of PNP-UDPGT|regulation of pnp-UDPGT activity|regulation of UDP glucuronic acid transferase activity|regulation of p-nitrophenol UDP-glucuronosyltransferase activity|regulation of uridine diphosphoglucuronate-1,2-diacylglycerol glucuronosyltransferase activity|regulation of 17beta-hydroxysteroid UDP-glucuronosyltransferase activity|regulation of UDP-glucuronate-bilirubin glucuronyltransferase activity|regulation of bilirubin UDP-glucuronosyltransferase activity|regulation of 1-naphthol glucuronyltransferase activity|regulation of UDP-glucuronosyltransferase activity|regulation of morphine glucuronyltransferase activity|regulation of phenyl-UDP-glucuronosyltransferase activity|regulation of uridine diphosphoglucuronate-bilirubin glucuronoside glucuronosyltransferase activity|regulation of p-hydroxybiphenyl UDP glucuronyltransferase activity|regulation of p-nitrophenol UDP-glucuronyltransferase activity|regulation of uridine diphosphoglucuronate-bilirubin glucuronosyltransferase activity|regulation of estriol UDPglucuronosyltransferase activity|regulation of uridine 5'-diphosphoglucuronyltransferase activity|regulation of 3-alpha-hydroxysteroid UDP-glucuronosyltransferase activity|regulation of UDP glucuronyltransferase activity|regulation of bilirubin glucuronyltransferase activity|regulation of uridine diphosphoglucuronate-4-hydroxybiphenyl glucuronosyltransferase activity|regulation of uridine diphosphoglucuronosyltransferase activity|regulation of bilirubin uridine diphosphoglucuronyltransferase activity|regulation of UDP-glucuronyltransferase activity|regulation of 4-hydroxybiphenyl UDP-glucuronosyltransferase activity|regulation of ciramadol UDP-glucuronyltransferase activity|regulation of bilirubin monoglucuronide glucuronyltransferase activity|regulation of p-nitrophenylglucuronosyltransferase activity|regulation of UDPglucuronate beta-D-glucuronosyltransferase (acceptor-unspecific) activity|regulation of uridine diphosphoglucuronate-estriol glucuronosyltransferase activity|regulation of UDP glucuronate-estriol glucuronosyltransferase activity|regulation of UDP-glucuronate-4-hydroxybiphenyl glucuronosyltransferase activity|regulation of 4-nitrophenol UDPGT activity|regulation of 4-methylumbelliferone UDP-glucuronosyltransferase activity|regulation of bilirubin UDPGT activity|regulation of uridine diphosphate glucuronyltransferase activity|regulation of uridine diphosphoglucuronate-estradiol glucuronosyltransferase activity|regulation of UDP glucuronate-estradiol-glucuronosyltransferase activity|regulation of UDPGT activity|regulation of UDP glucuronosyltransferase activity|regulation of estrone UDPglucuronosyltransferase activity|regulation of uridine diphosphoglucuronate-estriol 16-alpha-glucuronosyltransferase activity|regulation of 1-naphthol-UDP-glucuronosyltransferase activity|regulation of 3-OH androgenic UDPGT activity|regulation of GT activity					i2 UDP-glucuronosyltransferase splice species alter glucuronidation activity of i1 UDP-glucuronosyltransferase splice species		rl	2015-05-15T08:44:20Z					biological_process											owl:Class	
GO:0034342	biolink:NamedThing	response to type III interferon	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a type III interferon stimulus. Interferon lambda is the only member of the type III interferon found so far.	tmpzr1t_l9r_go_relaxed.owl	response to interferon-lambda|response to type III IFN													biological_process											owl:Class	
GO:0120045	biolink:NamedThing	stereocilium maintenance	The organization process that preserves a stereocilium in a stable functional or structural state.	tmpzr1t_l9r_go_relaxed.owl								krc	2017-05-15T20:55:13Z					biological_process											owl:Class	
GO:0060122	biolink:NamedThing	inner ear receptor cell stereocilium organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a stereocilium. A stereocilium is an actin-based protrusion from the apical surface of inner ear receptor cells.	tmpzr1t_l9r_go_relaxed.owl	inner ear hair cell receptor stereocilium organization|inner ear receptor stereocilium organization and biogenesis|inner ear receptor stereocilium organisation													biological_process											owl:Class	
GO:0034082	biolink:NamedThing	type II polyketide synthase complex	A polyketide synthase complex that consists of several different polypeptide chains, each of which catalyzes a single reaction.	tmpzr1t_l9r_go_relaxed.owl	type II PKS|type II polyketide synthase|type II PKS complex													cellular_component											owl:Class	
GO:0034081	biolink:NamedThing	polyketide synthase complex	A protein complex that carries out enzymatic reactions involved in the biosynthesis of polyketides, any of a diverse group of natural products synthesized via linear poly-beta-ketones.	tmpzr1t_l9r_go_relaxed.owl	PKS complex|PKS													cellular_component											owl:Class	
GO:0004747	biolink:NamedThing	ribokinase activity	Catalysis of the reaction: ATP + D-ribose = ADP + D-ribose 5-phosphate.	tmpzr1t_l9r_go_relaxed.owl	deoxyribokinase activity|D-ribokinase activity|ATP:D-ribose 5-phosphotransferase activity|ribokinase (phosphorylating)				EC:2.7.1.15|MetaCyc:RIBOKIN-RXN|RHEA:13697|Reactome:R-HSA-8955844									molecular_function											owl:Class	
GO:0019200	biolink:NamedThing	carbohydrate kinase activity	Catalysis of the transfer of a phosphate group, usually from ATP, to a carbohydrate substrate molecule.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-8931653									molecular_function											owl:Class	
GO:0048202	biolink:NamedThing	clathrin coating of Golgi vesicle	The addition of clathrin and adaptor proteins to Golgi membranes during the formation of transport vesicles, forming a vesicle coat.	tmpzr1t_l9r_go_relaxed.owl	clathrin coating of Golgi-derived vesicle													biological_process											owl:Class	
GO:0048200	biolink:NamedThing	Golgi transport vesicle coating	The addition of specific coat proteins to Golgi membranes during the formation of transport vesicles.	tmpzr1t_l9r_go_relaxed.owl	dictyosome transport vesicle coating													biological_process											owl:Class	
GO:0030130	biolink:NamedThing	clathrin coat of trans-Golgi network vesicle	A clathrin coat found on a vesicle of the trans-Golgi network.	tmpzr1t_l9r_go_relaxed.owl	clathrin coat of TGN vesicle													cellular_component											owl:Class	
GO:0030125	biolink:NamedThing	clathrin vesicle coat	A clathrin coat found on a vesicle.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0008309	biolink:NamedThing	double-stranded DNA exodeoxyribonuclease activity	Catalysis of the sequential cleavage of mononucleotides from a free 5' or 3' terminus of a double-stranded DNA molecule.	tmpzr1t_l9r_go_relaxed.owl	double-stranded DNA specific exodeoxyribonuclease activity													molecular_function											owl:Class	
GO:0016895	biolink:NamedThing	exodeoxyribonuclease activity, producing 5'-phosphomonoesters	Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acids by removing nucleotide residues from the 3' or 5' end to yield 5' phosphomonoesters.	tmpzr1t_l9r_go_relaxed.owl	exonuclease VIII activity|exodeoxyribonuclease activity, producing 5' phosphomonoesters				EC:3.1.11.-							GO:0008858		molecular_function											owl:Class	
GO:1901897	biolink:NamedThing	regulation of relaxation of cardiac muscle	Any process that modulates the frequency, rate or extent of relaxation of cardiac muscle.	tmpzr1t_l9r_go_relaxed.owl								rl	2013-02-06T21:26:58Z					biological_process											owl:Class	
GO:0005360	biolink:NamedThing	insulin-responsive glucose:proton symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucose(out) + H(out)+ = glucose(in) + H(in)+, in response to a stimulus by insulin. Symporter activity enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported together in the same direction in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy.	tmpzr1t_l9r_go_relaxed.owl	insulin-responsive hydrogen:glucose transporter activity|insulin-responsive hydrogen:glucose symporter activity|transepithelial hydrogen/glucose transporter activity													molecular_function											owl:Class	
GO:0005356	biolink:NamedThing	glucose:proton symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucose + H+ = glucose + H+. Symporter activity enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported together in the same direction in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy.	tmpzr1t_l9r_go_relaxed.owl	transepithelial hydrogen:glucose symporter activity|hydrogen:glucose symporter activity|hydrogen:glucose transporter activity|transepithelial hydrogen/glucose transporter activity|transepithelial hydrogen:glucose transporter activity											GO:0005361		molecular_function											owl:Class	
GO:0061203	biolink:NamedThing	striated muscle paramyosin thick filament assembly	The aggregation, arrangement and bonding together of proteins to form the paramyosin-based thick filaments of myofibrils in striated muscle.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-07-29T12:22:31Z					biological_process											owl:Class	
GO:0061204	biolink:NamedThing	paramyosin filament assembly or disassembly	The formation or disassembly of a filament composed of paramyosin molecules.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-07-29T12:26:38Z					biological_process											owl:Class	
GO:0099513	biolink:NamedThing	polymeric cytoskeletal fiber	A component of the cytoskeleton consisting of a homo or heteropolymeric fiber constructed from an indeterminate number of protein subunits.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:2000830	biolink:NamedThing	positive regulation of parathyroid hormone secretion	Any process that activates or increases the frequency, rate or extent of parathyroid hormone secretion.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of PTH secretion|positive regulation of parathormone secretion|positive regulation of parathyrin secretion							bf	2011-07-26T08:38:00Z					biological_process											owl:Class	
GO:2000828	biolink:NamedThing	regulation of parathyroid hormone secretion	Any process that modulates the frequency, rate or extent of parathyroid hormone secretion.	tmpzr1t_l9r_go_relaxed.owl	regulation of parathyrin secretion|regulation of PTH secretion|regulation of parathormone secretion							bf	2011-07-26T08:37:53Z					biological_process											owl:Class	
GO:0046494	biolink:NamedThing	rhizobactin 1021 metabolic process	The chemical reactions and pathways involving rhizobactin 1021, (E)-4-((3-(acetylhydroxyamino)propyl)-amino)-2-hydroxy-(2-(2-(3-(hydroxy(1-oxo-2-decenyl)amino)propyl)amino)-2-oxoethyl)-4-oxobutanoic acid, a siderophore produced by Sinorhizobium meliloti.	tmpzr1t_l9r_go_relaxed.owl	rhizobactin 1021 metabolism													biological_process											owl:Class	
GO:0022023	biolink:NamedThing	radial glial cell fate commitment in forebrain	The process in which the developmental fate of a cell becomes restricted such that it will develop into a radial glial cell in the forebrain.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0021898	biolink:NamedThing	commitment of multipotent stem cells to neuronal lineage in forebrain	The initial commitment of cells whereby the developmental fate of a cell becomes restricted such that it will develop into some type of neuron in the forebrain.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:2000297	biolink:NamedThing	negative regulation of synapse maturation	Any process that stops, prevents or reduces the frequency, rate or extent of synapse maturation.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of synaptic maturation							mah	2010-12-23T11:37:31Z					biological_process											owl:Class	
GO:1905809	biolink:NamedThing	negative regulation of synapse organization	Any process that stops, prevents or reduces the frequency, rate or extent of synapse organization.	tmpzr1t_l9r_go_relaxed.owl	inhibition of synapse morphogenesis|down-regulation of synapse organization|down regulation of synapse organization and biogenesis|negative regulation of synapse morphogenesis|inhibition of synapse organisation|inhibition of synapse organization|down regulation of synapse morphogenesis|inhibition of synapse organization and biogenesis|downregulation of synapse morphogenesis|downregulation of synapse organization|negative regulation of synapse organization and biogenesis|down-regulation of synapse development|downregulation of synapse development|negative regulation of synapse development|negative regulation of synapse organisation|downregulation of synapse organization and biogenesis|down regulation of synapse organisation|down regulation of synapse development|inhibition of synapse development|downregulation of synapse organisation|down-regulation of synapse morphogenesis|down-regulation of synapse organization and biogenesis|down regulation of synapse organization|down-regulation of synapse organisation							tb	2017-01-11T22:03:41Z					biological_process											owl:Class	
GO:0060450	biolink:NamedThing	positive regulation of hindgut contraction	Any process that increases the frequency, rate or extent of muscle contraction of the hindgut, the posterior part of the alimentary canal, including the rectum, and the large intestine.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0043134	biolink:NamedThing	regulation of hindgut contraction	Any process that modulates the frequency, rate or extent of muscle contraction of the hindgut, the posterior part of the alimentary canal, including the rectum, and the large intestine.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1904260	biolink:NamedThing	negative regulation of basement membrane assembly involved in embryonic body morphogenesis	Any process that stops, prevents or reduces the frequency, rate or extent of basement membrane assembly involved in embryonic body morphogenesis.	tmpzr1t_l9r_go_relaxed.owl	downregulation of basement membrane assembly involved in embryonic body morphogenesis|down regulation of basement membrane assembly involved in embryonic body morphogenesis|inhibition of basement membrane assembly involved in embryonic body morphogenesis|down-regulation of basement membrane assembly involved in embryonic body morphogenesis							als	2015-05-21T09:20:49Z					biological_process											owl:Class	
GO:1904259	biolink:NamedThing	regulation of basement membrane assembly involved in embryonic body morphogenesis	Any process that modulates the frequency, rate or extent of basement membrane assembly involved in embryonic body morphogenesis.	tmpzr1t_l9r_go_relaxed.owl								als	2015-05-21T09:20:43Z					biological_process											owl:Class	
GO:0090285	biolink:NamedThing	negative regulation of protein glycosylation in Golgi	Any process that decreases the rate, frequency, or extent of the addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid in any compartment of the Golgi apparatus.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of protein amino acid glycosylation in Golgi							tb	2010-02-18T02:43:55Z					biological_process											owl:Class	
GO:0015547	biolink:NamedThing	nalidixic acid transmembrane transporter activity	Enables the transfer of nalidixic acid from one side of a membrane to the other. Nalidixic acid is a synthetic antibiotic that interferes with DNA gyrase and inhibits prokaryotic replication.	tmpzr1t_l9r_go_relaxed.owl	carbonyl cyanide m-chlorophenylhydrazone/nalidixic acid/organomercurials:hydrogen antiporter activity|nalidixic acid transporter activity													molecular_function											owl:Class	
GO:0044303	biolink:NamedThing	axon collateral	Any of the smaller branches of an axon that emanate from the main axon cylinder.	tmpzr1t_l9r_go_relaxed.owl					NIF_Subcellular:sao1470140754			jl	2010-02-05T11:29:04Z					cellular_component											owl:Class	
GO:0019263	biolink:NamedThing	adamantanone catabolic process	The chemical reactions and pathways resulting in the breakdown of adamantanone, tricyclo(3.3.1.13,7)decanone, a white crystalline solid used as an intermediate for microelectronics in the production of photoresists.	tmpzr1t_l9r_go_relaxed.owl	adamantanone catabolism|adamantanone degradation|adamantanone breakdown				MetaCyc:P481-PWY									biological_process											owl:Class	
GO:2000392	biolink:NamedThing	regulation of lamellipodium morphogenesis	Any process that modulates the frequency, rate or extent of lamellipodium morphogenesis.	tmpzr1t_l9r_go_relaxed.owl	regulation of lamellipodium organization							mah	2011-02-22T11:18:58Z					biological_process											owl:Class	
GO:0051271	biolink:NamedThing	negative regulation of cellular component movement	Any process that stops, prevents, or reduces the frequency, rate or extent of the movement of a cellular component.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of cellular component motion													biological_process											owl:Class	
GO:0031163	biolink:NamedThing	metallo-sulfur cluster assembly	The incorporation of a metal and exogenous sulfur into a metallo-sulfur cluster.	tmpzr1t_l9r_go_relaxed.owl	metallo-sulfur cluster biosynthesis|metal-sulfur cluster assembly|metallo-sulphur cluster assembly													biological_process											owl:Class	
GO:0009617	biolink:NamedThing	response to bacterium	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a bacterium.	tmpzr1t_l9r_go_relaxed.owl	response to bacteria											GO:0009680|GO:0009618		biological_process											owl:Class	
GO:0075040	biolink:NamedThing	regulation of establishment of turgor in appressorium	Any process modulates the frequency, rate or extent of turgor formation in the symbiont appressorium.	tmpzr1t_l9r_go_relaxed.owl	regulation of turgor formation in appressorium													biological_process											owl:Class	
GO:0050094	biolink:NamedThing	methionine-glyoxylate transaminase activity	Catalysis of the reaction: L-methionine + glyoxylate = 4-methylthio-2-oxobutanoate + glycine.	tmpzr1t_l9r_go_relaxed.owl	L-methionine:glyoxylate aminotransferase activity|MGAT activity|methionine-glyoxylate aminotransferase activity				KEGG_REACTION:R00652|EC:2.6.1.73|RHEA:22884|MetaCyc:METHIONINE--GLYOXYLATE-TRANSAMINASE-RXN									molecular_function											owl:Class	
GO:0080169	biolink:NamedThing	cellular response to boron-containing substance deprivation	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of boron obtained from boron-containing substances.	tmpzr1t_l9r_go_relaxed.owl	cellular response to boron deprivation|cellular response to boron starvation							dhl	2010-09-23T05:10:00Z					biological_process											owl:Class	
GO:0062197	biolink:NamedThing	cellular response to chemical stress	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus indicating the organism is under stress.	tmpzr1t_l9r_go_relaxed.owl								dph	2019-12-10T14:42:03Z					biological_process											owl:Class	
GO:0019414	biolink:NamedThing	aerobic respiration, using sulfur or sulfate as electron donor	An aerobic respiration process in which a sulfur-containing molecule (hydrogen sulfide, sulfur, sulfite, thiosulfate, and various polythionates) is oxidized.	tmpzr1t_l9r_go_relaxed.owl	aerobic respiration, using sulphur or sulphate as electron donor													biological_process											owl:Class	
GO:0060336	biolink:NamedThing	negative regulation of interferon-gamma-mediated signaling pathway	Any process that decreases the rate, frequency or extent of the series of molecular events generated as a consequence of interferon-gamma binding to a cell surface receptor.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of type II IFN-mediated signaling pathway|negative regulation of type II interferon-mediated signaling pathway|negative regulation of gamma-interferon-mediated signaling pathway|negative regulation of immune interferon-mediated signaling pathway|negative regulation of interferon-gamma-mediated signalling pathway													biological_process											owl:Class	
GO:0034031	biolink:NamedThing	ribonucleoside bisphosphate catabolic process	The chemical reactions and pathways resulting in the breakdown of a ribonucleoside bisphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar.	tmpzr1t_l9r_go_relaxed.owl	ribonucleoside bisphosphate degradation|ribonucleoside bisphosphate catabolism|ribonucleoside bisphosphate breakdown													biological_process											owl:Class	
GO:0050837	biolink:NamedThing	peptide cross-linking via L-cysteinyl-L-selenocysteine	The formation of a selenide-sulfide bond to form the cystine-like L-cysteinyl-L-selenocysteine, as in vertebrate selenopeptide P.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0358									biological_process											owl:Class	
GO:0071420	biolink:NamedThing	cellular response to histamine	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a histamine stimulus. Histamine, the biogenic amine 2-(1H-imidazol-4-yl)ethanamine, is involved in local immune responses as well as regulating physiological function in the gut and acting as a neurotransmitter.	tmpzr1t_l9r_go_relaxed.owl	cellular response to histamine stimulus							mah	2009-12-14T04:09:25Z					biological_process											owl:Class	
GO:0034776	biolink:NamedThing	response to histamine	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a histamine stimulus. Histamine, the biogenic amine 2-(1H-imidazol-4-yl)ethanamine, is involved in local immune responses as well as regulating physiological function in the gut and acting as a neurotransmitter.	tmpzr1t_l9r_go_relaxed.owl	response to histamine stimulus													biological_process											owl:Class	
GO:1903747	biolink:NamedThing	regulation of establishment of protein localization to mitochondrion	Any process that modulates the frequency, rate or extent of establishment of protein localization to mitochondrion.	tmpzr1t_l9r_go_relaxed.owl	regulation of establishment of protein localisation to mitochondrion|regulation of establishment of protein localization in mitochondrion							krc	2014-12-12T22:18:09Z					biological_process											owl:Class	
GO:0070996	biolink:NamedThing	type 1 melanocortin receptor binding	Binding to a type 1 melanocortin receptor.	tmpzr1t_l9r_go_relaxed.owl	type 1 melanocortin receptor ligand							mah	2009-11-03T01:50:53Z					molecular_function											owl:Class	
GO:0031779	biolink:NamedThing	melanocortin receptor binding	Binding to a melanocortin receptor.	tmpzr1t_l9r_go_relaxed.owl	melanocortin receptor ligand													molecular_function											owl:Class	
GO:0032948	biolink:NamedThing	regulation of alpha-glucan metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving alpha-glucans.	tmpzr1t_l9r_go_relaxed.owl	regulation of alpha-glucan metabolism													biological_process											owl:Class	
GO:0021579	biolink:NamedThing	medulla oblongata morphogenesis	The process in which the anatomical structure of the medulla oblongata is generated and organized. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate.	tmpzr1t_l9r_go_relaxed.owl	medulla morphogenesis|myelencephalon morphogenesis													biological_process											owl:Class	
GO:0009789	biolink:NamedThing	positive regulation of abscisic acid-activated signaling pathway	Any process that activates or increases the frequency, rate or extent of abscisic acid (ABA) signaling.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of abscisic acid mediated signaling pathway|up regulation of abscisic acid mediated signaling|up-regulation of abscisic acid mediated signaling|positive regulation of abscisic acid mediated signalling|stimulation of abscisic acid mediated signaling|activation of abscisic acid mediated signaling|upregulation of abscisic acid mediated signaling													biological_process											owl:Class	
GO:2000491	biolink:NamedThing	positive regulation of hepatic stellate cell activation	Any process that activates or increases the frequency, rate or extent of hepatic stellate cell activation.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-03-14T03:49:48Z					biological_process											owl:Class	
GO:0072402	biolink:NamedThing	response to DNA integrity checkpoint signaling	A process that occurs in response to signals generated as a result of DNA integrity checkpoint signaling.	tmpzr1t_l9r_go_relaxed.owl	response to signal involved in DNA integrity checkpoint|DNA integrity checkpoint effector process							mah	2010-12-08T03:32:17Z					biological_process											owl:Class	
GO:0072396	biolink:NamedThing	response to cell cycle checkpoint signaling	A process that occurs in response to signals generated as a result of cell cycle checkpoint signaling.	tmpzr1t_l9r_go_relaxed.owl	G1/S transition checkpoint effector process|response to signal involved in cell cycle checkpoint|G2/M transition checkpoint effector process|response to signal involved in G1/S transition checkpoint|response to G1/S transition checkpoint signaling|cell cycle checkpoint effector process|response to signal involved in G2/M transition checkpoint|response to G2/M transition checkpoint signaling							mah	2010-12-08T03:05:46Z			GO:0072405|GO:0072408		biological_process											owl:Class	
GO:0046959	biolink:NamedThing	habituation	A decrease in a behavioral response to a repeated stimulus. This is exemplified by the failure of a person to show a startle response to a loud noise that has been repeatedly presented.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Habituation									biological_process											owl:Class	
GO:0046958	biolink:NamedThing	nonassociative learning	A simple form of learning whereby the repeated presence of a stimulus leads to a change in the probability or strength of the response to that stimulus. There is no association of one type of stimulus with another, rather it is a generalized response to the environment.	tmpzr1t_l9r_go_relaxed.owl	unconditional response													biological_process											owl:Class	
GO:2000711	biolink:NamedThing	positive regulation of maintenance of meiotic sister chromatid cohesion, centromeric	Any process that activates or increases the frequency, rate or extent of maintenance of meiotic sister chromatid cohesion in the centromeric region.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of maintenance of meiotic sister chromatin cohesion at centromere|positive regulation of maintenance of sister chromatin cohesion at centromere at meiosis I|positive regulation of maintenance of centromeric meiotic sister chromatin cohesion							mah	2011-06-01T12:41:18Z					biological_process											owl:Class	
GO:0034096	biolink:NamedThing	positive regulation of maintenance of meiotic sister chromatid cohesion	Any process that increases the extent to which the association between sister chromatids of a replicated chromosome is maintained during a meiotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0090634	biolink:NamedThing	microglial cell mediated cytotoxicity	The directed killing of a target cell by a microglial cell.	tmpzr1t_l9r_go_relaxed.owl								tb	2015-04-14T14:04:54Z					biological_process											owl:Class	
GO:0002444	biolink:NamedThing	myeloid leukocyte mediated immunity	Any process involved in the carrying out of an immune response by a myeloid leukocyte.	tmpzr1t_l9r_go_relaxed.owl	myeloid leucocyte mediated immunity|myeloid leukocyte immune effector process|myeloid leucocyte immune effector process													biological_process											owl:Class	
GO:0015621	biolink:NamedThing	ferric triacetylfusarinine C transmembrane transporter activity	Enables the transfer of ferric triacetylfusarinine C from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0035158	biolink:NamedThing	regulation of tube diameter, open tracheal system	Ensuring that a tube in an open tracheal system is of the correct diameter. When primary branches form their lumens are small (less than 2 micrometers) in caliber and must undergo regulated expansion during larval life to reach their mature size.	tmpzr1t_l9r_go_relaxed.owl	tracheal tube expansion|tracheal tube dilation|regulation of tracheal tube diameter													biological_process											owl:Class	
GO:0035159	biolink:NamedThing	regulation of tube length, open tracheal system	Ensuring that a tube in an open tracheal system is of the correct length.	tmpzr1t_l9r_go_relaxed.owl	regulation of tracheal tube length|tracheal tube elongation													biological_process											owl:Class	
GO:0102076	biolink:NamedThing	beta,beta-carotene-9',10'-cleaving oxygenase activity	Catalysis of the reaction: beta-carotene + O2 <=> 10'-apo-beta-carotenal + beta-ionone.	tmpzr1t_l9r_go_relaxed.owl					EC:1.13.11.71|RHEA:26389|MetaCyc:RXN-10741									molecular_function											owl:Class	
GO:1900409	biolink:NamedThing	positive regulation of cellular response to oxidative stress	Any process that activates or increases the frequency, rate or extent of cellular response to oxidative stress.	tmpzr1t_l9r_go_relaxed.owl	upregulation of adaptive response to oxidative stress|up-regulation of cellular response to oxidative stress|up regulation of adaptive response to oxidative stress|activation of adaptive response to oxidative stress|upregulation of cellular response to oxidative stress|up regulation of cellular response to oxidative stress|positive regulation of adaptive response to oxidative stress|up-regulation of adaptive response to oxidative stress|activation of cellular response to oxidative stress							mah	2012-04-20T03:31:16Z					biological_process											owl:Class	
GO:0004081	biolink:NamedThing	bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity	Catalysis of the reaction: P(1),P(4)-bis(5'-nucleosyl)tetraphosphate + H2O = NTP + NMP. Acts on bis(5'-guanosyl)-, bis(5'-xanthosyl)-, bis(5'-adenosyl)- and bis(5'-uridyl)-tetraphosphate.	tmpzr1t_l9r_go_relaxed.owl	Ap4A hydrolase activity|dinucleoside tetraphosphatase activity|diadenosinetetraphosphatase (asymmetrical) activity|diadenosine 5',5'''-P1,P4-tetraphosphate asymmetrical hydrolase activity|Ap4Aase activity|bis(5'-adenosyl)-tetraphosphatase activity|dinucleosidetetraphosphatase (asymmetrical) activity|bis(5'-guanosyl)-tetraphosphatase activity|Ap(4)A hydrolase activity|P1,P4-bis(5'-nucleosyl)-tetraphosphate nucleotidohydrolase activity|diadenosine 5',5'''-P1,P4-tetraphosphate hydrolase|diadenosine P1,P4-tetraphosphatase activity|diguanosinetetraphosphatase (asymmetrical) activity|1-P,4-P-bis(5'-nucleosyl)-tetraphosphate nucleotidohydrolase activity|Ap(4)Aase activity|diadenosine 5',5'''-P(1),P(4)-tetraphosphate asymmetrical hydrolase activity				EC:3.6.1.17|MetaCyc:3.6.1.17-RXN|Reactome:R-HSA-5696197|RHEA:22484									molecular_function											owl:Class	
GO:0008796	biolink:NamedThing	bis(5'-nucleosyl)-tetraphosphatase activity	Catalysis of the hydrolysis of P(1),P(4)-bis(5'-nucleosyl)tetraphosphate into two nucleotides.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0021517	biolink:NamedThing	ventral spinal cord development	The process whose specific outcome is the progression of the ventral region of the spinal cord over time, from its formation to the mature structure. The neurons of the ventral region of the mature spinal cord participate in motor output.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0033449	biolink:NamedThing	GUU codon-amino acid adaptor activity	A triplet codon-amino acid adaptor activity that recognizes a GUU codon.	tmpzr1t_l9r_go_relaxed.owl	valine tRNA|GTT codon-amino acid adaptor activity					Note that in the standard genetic code, GTT codes for valine.								molecular_function											owl:Class	
GO:0061907	biolink:NamedThing	negative regulation of AMPA receptor activity	Any process that stops, prevents or reduces the frequency, rate or extent of AMPA glutamate receptor activity.	tmpzr1t_l9r_go_relaxed.owl								dph	2017-06-29T11:55:11Z					biological_process											owl:Class	
GO:2000311	biolink:NamedThing	regulation of AMPA receptor activity	Any process that modulates the frequency, rate or extent of AMPA selective glutamate receptor activity.	tmpzr1t_l9r_go_relaxed.owl	regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity							bf	2011-01-18T10:10:28Z					biological_process											owl:Class	
GO:1905860	biolink:NamedThing	positive regulation of heparan sulfate proteoglycan binding	Any process that activates or increases the frequency, rate or extent of heparan sulfate proteoglycan binding.	tmpzr1t_l9r_go_relaxed.owl	activation of heparan sulfate proteoglycan binding|up regulation of heparan sulfate proteoglycan binding|up-regulation of heparin proteoglycan binding|activation of heparin proteoglycan binding|upregulation of heparin proteoglycan binding|positive regulation of heparin proteoglycan binding|upregulation of heparan sulfate proteoglycan binding|up-regulation of heparan sulfate proteoglycan binding|up regulation of heparin proteoglycan binding							bc	2017-01-23T14:25:27Z					biological_process											owl:Class	
GO:0034271	biolink:NamedThing	phosphatidylinositol 3-kinase complex, class III, type I	A class III phosphatidylinositol 3-kinase complex that is involved in autophagy. In budding yeast, this complex consists of Vps30p, Vps34p, Apg14p and Vps15p.	tmpzr1t_l9r_go_relaxed.owl	autophagy-specific phosphatidylinositol 3-kinase (PtdIns3K) complex|phosphatidylinositol 3-kinase complex I|PtdIns-3-kinase complex I					Note that this term should not be confused with '1-phosphatidylinositol-4-phosphate 3-kinase, class IA complex; GO:0005943' or '1-phosphatidylinositol-4-phosphate 3-kinase, class IB complex ; GO:0005944'.								cellular_component											owl:Class	
GO:0035032	biolink:NamedThing	phosphatidylinositol 3-kinase complex, class III	A phosphatidylinositol 3-kinase complex that contains a catalytic class III phosphoinositide 3-kinase (PI3K) subunit bound to a regulatory (adaptor) subunit. Additional adaptor proteins may be present. Class III PI3Ks have a substrate specificity restricted to phosphatidylinositol (PI).	tmpzr1t_l9r_go_relaxed.owl	class III PI3K complex|phosphoinositide 3-kinase complex, class III													cellular_component											owl:Class	
GO:0051611	biolink:NamedThing	regulation of serotonin uptake	Any process that modulates the frequency, rate or extent of the directed movement of the monoamine neurotransmitter serotonin into a cell.	tmpzr1t_l9r_go_relaxed.owl	regulation of serotonin import|regulation of 5HT uptake|regulation of 5-hydroxytryptamine uptake|regulation of 5-HT uptake													biological_process											owl:Class	
GO:0051580	biolink:NamedThing	regulation of neurotransmitter uptake	Any process that modulates the frequency, rate or extent of the directed movement of a neurotransmitter into a neuron or glial cell.	tmpzr1t_l9r_go_relaxed.owl	regulation of neurotransmitter reuptake|regulation of neurotransmitter import													biological_process											owl:Class	
GO:0004087	biolink:NamedThing	carbamoyl-phosphate synthase (ammonia) activity	Catalysis of the reaction: 2 ATP + CO(2) + H(2)O + NH(4)(+) = 2 ADP + carbamoyl phosphate + 5 H(+) + phosphate.	tmpzr1t_l9r_go_relaxed.owl	carbon-dioxide--ammonia ligase activity|carbamoylphosphate synthetase (ammonia) activity|carbamoylphosphate synthase activity|carbmoylphosphate synthetase activity|carbamoyl-phosphate synthetase (ammonia) activity|carbon-dioxide:ammonia ligase (ADP-forming, carbamate-phosphorylating)|carbamylphosphate synthetase activity|carbamoylphosphate synthase (ammonia)|carbamylphosphate synthetase I|CPS I activity|carbamoyl phosphate synthase (ammonia) activity|carbamoyl-phosphate synthetase I activity				KEGG_REACTION:R00149|RHEA:10624|Reactome:R-HSA-70555|EC:6.3.4.16|MetaCyc:6.3.4.16-RXN									molecular_function											owl:Class	
GO:1900831	biolink:NamedThing	D-leucine metabolic process	The chemical reactions and pathways involving D-leucine.	tmpzr1t_l9r_go_relaxed.owl	D-leucine metabolism							se	2012-06-06T09:37:17Z					biological_process											owl:Class	
GO:0032116	biolink:NamedThing	SMC loading complex	A protein complex required for the loading of a structural maintenance of chromosome (SMC) complex, such as cohesin, condensin or SMC5/SMC6, onto DNA. Appears to be eukaryotically conserved.	tmpzr1t_l9r_go_relaxed.owl	chromatin loading complex|SCC2/SCC4 loading complex|cohesin loading complex													cellular_component											owl:Class	
GO:0007191	biolink:NamedThing	adenylate cyclase-activating dopamine receptor signaling pathway	The series of molecular signals generated as a consequence of a dopamine receptor binding to its physiological ligand, where the pathway proceeds with activation of adenylyl cyclase and a subsequent increase in the concentration of cyclic AMP (cAMP).	tmpzr1t_l9r_go_relaxed.owl	activation of adenylate cyclase activity by dopamine receptor signaling pathway|activation of adenylate cyclase activity by dopamine receptor signalling pathway|dopamine receptor, adenylate cyclase activating pathway|dopamine receptor, adenylyl cyclase activating pathway													biological_process											owl:Class	
GO:0007212	biolink:NamedThing	dopamine receptor signaling pathway	The series of molecular signals generated as a consequence of a dopamine receptor binding to one of its physiological ligands.	tmpzr1t_l9r_go_relaxed.owl	dopamine receptor signalling pathway													biological_process											owl:Class	
GO:0010518	biolink:NamedThing	positive regulation of phospholipase activity	Any process that increases the frequency, rate or extent of phospholipase activity, the hydrolysis of a phospholipid.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0060193	biolink:NamedThing	positive regulation of lipase activity	Any process that increases the frequency, rate or extent of lipase activity, the hydrolysis of a lipid or phospholipid.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0000156	biolink:NamedThing	phosphorelay response regulator activity	Responds to a phosphorelay sensor to initiate a change in cell state or activity. The activity of the response regulator is regulated by transfer of a phosphate from a histidine residue in the sensor, to an aspartate residue in the response regulator. Many but not all response regulators act as transcriptional regulators to elicit a response.	tmpzr1t_l9r_go_relaxed.owl	two-component response regulator activity	https://github.com/geneontology/go-ontology/issues/15611												molecular_function											owl:Class	
GO:0003720	biolink:NamedThing	telomerase activity	Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). Catalyzes extension of the 3'- end of a DNA strand by one deoxynucleotide at a time using an internal RNA template that encodes the telomeric repeat sequence.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-164617|Reactome:R-HSA-163090									molecular_function											owl:Class	
GO:0003964	biolink:NamedThing	RNA-directed DNA polymerase activity	Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). Catalyzes RNA-template-directed extension of the 3'- end of a DNA strand by one deoxynucleotide at a time.	tmpzr1t_l9r_go_relaxed.owl	deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (RNA-directed) activity|RNA-dependent deoxyribonucleate nucleotidyltransferase activity|RNA-directed DNA polymerase, transposon encoded|RNA-directed DNA polymerase, group II intron encoded|RNA revertase activity|revertase activity|reverse transcriptase activity|DNA nucleotidyltransferase (RNA-directed) activity|RNA-dependent DNA polymerase activity|RNA-instructed DNA polymerase activity|RT				MetaCyc:RNA-DIRECTED-DNA-POLYMERASE-RXN|EC:2.7.7.49|Reactome:R-HSA-164520|Reactome:R-HSA-164504									molecular_function											owl:Class	
GO:2001030	biolink:NamedThing	negative regulation of cellular glucuronidation	Any process that stops, prevents or reduces the frequency, rate or extent of cellular glucuronidation.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of cellular glucuronide biosynthetic process|negative regulation of cellular glucuronoside biosynthesis|negative regulation of cellular glucuronoside biosynthetic process|negative regulation of cellular glucuronide biosynthesis							rl	2011-08-22T01:10:56Z					biological_process											owl:Class	
GO:2001029	biolink:NamedThing	regulation of cellular glucuronidation	Any process that modulates the frequency, rate or extent of cellular glucuronidation.	tmpzr1t_l9r_go_relaxed.owl	regulation of cellular glucuronide biosynthesis|regulation of cellular glucuronoside biosynthetic process|regulation of cellular glucuronide biosynthetic process|regulation of cellular glucuronoside biosynthesis							rl	2011-08-22T01:10:52Z					biological_process											owl:Class	
GO:0005834	biolink:NamedThing	heterotrimeric G-protein complex	Any of a family of heterotrimeric GTP-binding and hydrolyzing proteins; they belong to a superfamily of GTPases that includes monomeric proteins such as EF-Tu and RAS. Heterotrimeric G-proteins consist of three subunits; the alpha subunit contains the guanine nucleotide binding site and possesses GTPase activity; the beta and gamma subunits are tightly associated and function as a beta-gamma heterodimer; extrinsic plasma membrane proteins (cytoplasmic face) that function as a complex to transduce signals from G protein-coupled receptors to an effector protein.	tmpzr1t_l9r_go_relaxed.owl	heterotrimeric G-protein GTPase, alpha-subunit|heterotrimeric G-protein GTPase activity|heterotrimeric G-protein GTPase, beta-subunit|heterotrimeric G-protein GTPase, gamma-subunit					See also the molecular function term 'G protein-coupled receptor activity ; GO:0004930'.								cellular_component											owl:Class	
GO:0004325	biolink:NamedThing	ferrochelatase activity	Catalysis of the reaction: protoheme = Fe(2+) + protoporphyrin IX.	tmpzr1t_l9r_go_relaxed.owl	heme synthetase activity|protoheme ferro-lyase (protoporphyrin-forming)|protoheme ferro-lyase activity|heme synthase activity|iron chelatase activity|ferro-protoporphyrin chelatase activity|protoheme ferrolyase activity				RHEA:22584|EC:4.99.1.1|MetaCyc:PROTOHEMEFERROCHELAT-RXN|KEGG_REACTION:R00310|Reactome:R-HSA-189465									molecular_function											owl:Class	
GO:0039004	biolink:NamedThing	specification of pronephric proximal tubule identity	The process in which the proximal tubule of the pronephric nephron acquires its identity.	tmpzr1t_l9r_go_relaxed.owl								bf	2010-07-02T09:30:30Z					biological_process											owl:Class	
GO:0039005	biolink:NamedThing	specification of pronephric tubule identity	The process in which the tubules arranged along the proximal/distal axis of the pronephric nephron acquire their identity.	tmpzr1t_l9r_go_relaxed.owl								bf	2010-07-02T09:33:56Z					biological_process											owl:Class	
GO:0008062	biolink:NamedThing	eclosion rhythm	The timing of the emergence of the adult fly from its pupal case, which usually occurs at dawn.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0048512	biolink:NamedThing	circadian behavior	The specific behavior of an organism that recurs with a regularity of approximately 24 hours.	tmpzr1t_l9r_go_relaxed.owl	circadian rhythm behavior													biological_process											owl:Class	
GO:1990425	biolink:NamedThing	ryanodine receptor complex	A voltage-gated calcium-release channel complex of the sarcoplasmic or endoplasmic reticulum. It plays an important role in the excitation-contraction (E-C) coupling of muscle cells. RyR comprises a family of ryanodine receptors, widely expressed throughout the animal kingdom.	tmpzr1t_l9r_go_relaxed.owl	RyR					An example of this is RyR1 in rabbit (P11716) in PMID:2550460 (inferred from electron microscopy).		anm	2014-07-24T09:36:41Z					cellular_component											owl:Class	
GO:0005891	biolink:NamedThing	voltage-gated calcium channel complex	A protein complex that forms a transmembrane channel through which calcium ions may pass in response to changes in membrane potential.	tmpzr1t_l9r_go_relaxed.owl	voltage-dependent calcium channel complex|voltage gated calcium channel complex|voltage-sensitive calcium channel complex													cellular_component											owl:Class	
GO:0070189	biolink:NamedThing	kynurenine metabolic process	The chemical reactions and pathways involving kynurenine, the amino acid 3-(2-aminobenzoyl)-alanine.	tmpzr1t_l9r_go_relaxed.owl	kynurenine metabolism													biological_process											owl:Class	
GO:2000980	biolink:NamedThing	regulation of inner ear receptor cell differentiation	Any process that modulates the frequency, rate or extent of inner ear receptor cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	regulation of inner ear hair cell differentiation							yaf	2011-08-03T02:38:43Z					biological_process											owl:Class	
GO:1900510	biolink:NamedThing	negative regulation of pentose catabolic process to ethanol	Any process that stops, prevents or reduces the frequency, rate or extent of pentose catabolic process to ethanol.	tmpzr1t_l9r_go_relaxed.owl	downregulation of pentose catabolism to ethanol|inhibition of pentose catabolic process to ethanol|downregulation of pentose catabolic process to ethanol|down-regulation of pentose catabolic process to ethanol|negative regulation of pentose catabolism to ethanol|down-regulation of pentose catabolism to ethanol|down regulation of pentose catabolic process to ethanol|inhibition of pentose catabolism to ethanol|down regulation of pentose catabolism to ethanol							tt	2012-05-02T04:04:51Z					biological_process											owl:Class	
GO:1900509	biolink:NamedThing	regulation of pentose catabolic process to ethanol	Any process that modulates the frequency, rate or extent of pentose catabolic process to ethanol.	tmpzr1t_l9r_go_relaxed.owl	regulation of pentose catabolism to ethanol							tt	2012-05-02T04:04:40Z					biological_process											owl:Class	
GO:0032141	biolink:NamedThing	single cytosine insertion binding	Binding to a double-stranded DNA region containing a single cytosine insertion or a deletion that results in an unpaired cytosine.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0032138	biolink:NamedThing	single base insertion or deletion binding	Binding to a double-stranded DNA region containing a single base insertion or deletion.	tmpzr1t_l9r_go_relaxed.owl	single base insertion binding													molecular_function											owl:Class	
GO:0086078	biolink:NamedThing	gap junction channel activity involved in bundle of His cell-Purkinje myocyte electrical coupling	A wide pore channel activity that enables a direct cytoplasmic connection from a bundle of His cell to a Purkinje myocyte. The gap junction passes electrical signals between the cells contributing to cardiac conduction.	tmpzr1t_l9r_go_relaxed.owl								dph	2011-11-22T10:34:13Z					molecular_function											owl:Class	
GO:0000031	biolink:NamedThing	mannosylphosphate transferase activity	Catalysis of the transfer of a mannosylphosphate group from one compound to another.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0046147	biolink:NamedThing	tetrahydrobiopterin catabolic process	The chemical reactions and pathways resulting in the breakdown of tetrahydrobiopterin, the reduced form of biopterin (2-amino-4-hydroxy-6-(1,2-dihydroxypropyl)-pteridine). It functions as a hydroxylation coenzyme, e.g. in the conversion of phenylalanine to tyrosine.	tmpzr1t_l9r_go_relaxed.owl	5,6,7,8-tetrahydrobiopterin catabolic process|tetrahydrobiopterin catabolism|tetrahydrobiopterin degradation|tetrahydrobiopterin breakdown													biological_process											owl:Class	
GO:0034313	biolink:NamedThing	diol catabolic process	The chemical reactions and pathways resulting in the breakdown of a diol, any alcohol containing two hydroxyl groups attached to saturated carbon atoms.	tmpzr1t_l9r_go_relaxed.owl	diol catabolism|diol degradation|diol breakdown|dihydric alcohol catabolic process													biological_process											owl:Class	
GO:0035231	biolink:NamedThing	cytoneme assembly	Formation of a cytoneme, a long, thin and polarized actin-based cytoplasmic extension that projects from a cell.	tmpzr1t_l9r_go_relaxed.owl	cytoneme biogenesis													biological_process											owl:Class	
GO:1900856	biolink:NamedThing	negative regulation of fumitremorgin B biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of fumitremorgin B biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	downregulation of fumitremorgin B biosynthetic process|down-regulation of fumitremorgin B biosynthetic process|down regulation of fumitremorgin B biosynthetic process							di	2012-06-07T09:51:01Z					biological_process											owl:Class	
GO:1900855	biolink:NamedThing	regulation of fumitremorgin B biosynthetic process	Any process that modulates the frequency, rate or extent of fumitremorgin B biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of fumitremorgin B anabolism|regulation of Lanosulin synthesis|regulation of Lanosulin formation|regulation of Lanosulin biosynthetic process|regulation of fumitremorgin B biosynthesis|regulation of Lanosulin biosynthesis|regulation of fumitremorgin B synthesis|regulation of Lanosulin anabolism|regulation of fumitremorgin B formation							di	2012-06-07T09:50:37Z					biological_process											owl:Class	
GO:2000319	biolink:NamedThing	regulation of T-helper 17 cell differentiation	Any process that modulates the frequency, rate or extent of T-helper 17 cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	regulation of T-helper 17 cell development							mah	2011-01-18T01:43:48Z					biological_process											owl:Class	
GO:0045622	biolink:NamedThing	regulation of T-helper cell differentiation	Any process that modulates the frequency, rate or extent of T-helper cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	regulation of T-helper cell development					Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.								biological_process											owl:Class	
GO:2000049	biolink:NamedThing	positive regulation of cell-cell adhesion mediated by cadherin	Any process that activates or increases the frequency, rate or extent of cell-cell adhesion mediated by cadherin.	tmpzr1t_l9r_go_relaxed.owl								jl	2010-08-20T12:56:57Z					biological_process											owl:Class	
GO:0034473	biolink:NamedThing	U1 snRNA 3'-end processing	Any process involved in forming the mature 3' end of a U1 snRNA molecule.	tmpzr1t_l9r_go_relaxed.owl	U1 snRNA 3' end processing													biological_process											owl:Class	
GO:1905135	biolink:NamedThing	biotin import across plasma membrane	The directed movement of biotin from outside of a cell, across the plasma membrane and into the cytosol.	tmpzr1t_l9r_go_relaxed.owl	biotin import into cell|biotin import							jl	2012-12-05T16:30:20Z			GO:0044756|GO:1901689		biological_process											owl:Class	
GO:1900577	biolink:NamedThing	gerfelin catabolic process	The chemical reactions and pathways resulting in the breakdown of gerfelin.	tmpzr1t_l9r_go_relaxed.owl	gerfelin degradation|gerfelin catabolism|gerfelin breakdown							di	2012-05-15T06:42:39Z					biological_process											owl:Class	
GO:1900576	biolink:NamedThing	gerfelin metabolic process	The chemical reactions and pathways involving gerfelin.	tmpzr1t_l9r_go_relaxed.owl	gerfelin metabolism							di	2012-05-15T06:42:19Z					biological_process											owl:Class	
GO:1905094	biolink:NamedThing	regulation of apolipoprotein A-I-mediated signaling pathway	Any process that modulates the frequency, rate or extent of apolipoprotein A-I-mediated signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	regulation of apolipoprotein A-I-mediated signalling pathway							bc	2016-03-31T11:33:48Z					biological_process											owl:Class	
GO:0050773	biolink:NamedThing	regulation of dendrite development	Any process that modulates the frequency, rate or extent of dendrite development.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0030345	biolink:NamedThing	structural constituent of tooth enamel	The action of a molecule that contributes to the structural integrity of tooth enamel.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0030021	biolink:NamedThing	extracellular matrix structural constituent conferring compression resistance	A constituent of the extracellular matrix that enables the matrix to resist compressive forces; often a proteoglycan.	tmpzr1t_l9r_go_relaxed.owl	core matrisome|core extracellular matrix					Extracellular matrix proteoglycans may be annotated to this term. PMID:8346704								molecular_function											owl:Class	
GO:0019383	biolink:NamedThing	(+)-camphor catabolic process	The chemical reactions and pathways resulting in the breakdown of (+)-camphor, a bicyclic monoterpene ketone.	tmpzr1t_l9r_go_relaxed.owl	(+)-camphor degradation|(+)-camphor breakdown|(+)-camphor catabolism				MetaCyc:P601-PWY									biological_process											owl:Class	
GO:1990942	biolink:NamedThing	mitotic metaphase chromosome recapture	A mechanism to recapture 'lost' chromosomes (chromosomes which have become detached from the spindle) during metaphase of mitotic chromosome segregation. Chromosomes with unattached kinetochores are migrated along (non polar) spindle microtubules to the mitotic spindle pole body by a combination of microtubule depolymerisation and 'kinetochore sliding' (migration of the chromosome along the microtubule). The chromosome subsequently migrates along the polar spindle microtubule to the metaphase plate.	tmpzr1t_l9r_go_relaxed.owl	microtubule sliding involved in mitotic metaphase chromosome recapture|microtubule sliding involved in metaphase chromosome retrieval to the spindle pole body|microtubule sliding involved in kinetochore retrieval|microtubule sliding involved in sister kinetochore recapture|sister kinetochore recapture|kinetochore retrieval|metaphase chromosome retrieval to the spindle pole body							vw	2016-04-06T14:41:56Z			GO:1905185		biological_process											owl:Class	
GO:0051303	biolink:NamedThing	establishment of chromosome localization	The directed movement of a chromosome to a specific location.	tmpzr1t_l9r_go_relaxed.owl	chromosome positioning|establishment of chromosome localisation													biological_process											owl:Class	
GO:2000760	biolink:NamedThing	negative regulation of N-terminal peptidyl-lysine acetylation	Any process that stops, prevents or reduces the frequency, rate or extent of N-terminal peptidyl-lysine acetylation.	tmpzr1t_l9r_go_relaxed.owl								yaf	2011-06-17T12:58:20Z					biological_process											owl:Class	
GO:1903318	biolink:NamedThing	negative regulation of protein maturation	Any process that stops, prevents or reduces the frequency, rate or extent of protein maturation.	tmpzr1t_l9r_go_relaxed.owl	downregulation of protein maturation|down regulation of protein maturation|down-regulation of protein maturation|inhibition of protein maturation							vw	2014-08-18T12:59:15Z					biological_process											owl:Class	
GO:1901117	biolink:NamedThing	cephamycin C catabolic process	The chemical reactions and pathways resulting in the breakdown of cephamycin C.	tmpzr1t_l9r_go_relaxed.owl	cephamycin C catabolism|cephamycin C degradation|cephamycin C breakdown							yaf	2012-07-11T03:07:13Z					biological_process											owl:Class	
GO:0097288	biolink:NamedThing	7-cyano-7-deazaguanine biosynthetic process	The chemical reactions and pathways resulting in the formation of the Q nucleoside precursor 7-cyano-7-deazaguanine, also known as 2-amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile or preQo.	tmpzr1t_l9r_go_relaxed.owl	7-cyano-7-deazaguanine biosynthesis|7-cyano-7-deazaguanine synthesis|7-cyano-7-deazaguanine formation|7-cyano-7-deazaguanine anabolism							pr	2012-04-25T10:53:47Z					biological_process											owl:Class	
GO:0150050	biolink:NamedThing	postsynaptic septin cytoskeleton	The portion of the septin cytoskeleton contained within the postsynapse.	tmpzr1t_l9r_go_relaxed.owl								bc	2018-04-26T14:45:52Z					cellular_component											owl:Class	
GO:0099571	biolink:NamedThing	postsynaptic cytoskeleton	The portion of the cytoskeleton contained within the postsynapse.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0042300	biolink:NamedThing	beta-amyrin synthase activity	Catalysis of the reaction: (S)-2,3-epoxysqualene = beta-amyrin. This reaction is the cyclization and rearrangement of (S)-2,3-epoxysqualene (2,3-oxidosqualene) into beta-amyrin.	tmpzr1t_l9r_go_relaxed.owl	oxidosqualene:beta-amyrin cyclase activity				MetaCyc:RXN-7570|EC:5.4.99.-									molecular_function											owl:Class	
GO:0005943	biolink:NamedThing	phosphatidylinositol 3-kinase complex, class IA	A class I phosphatidylinositol 3-kinase complex that possesses 1-phosphatidylinositol-4-phosphate 3-kinase activity; comprises a catalytic class IA phosphoinositide 3-kinase (PI3K) subunit and an associated SH2 domain-containing regulatory subunit that is a member of a family of related proteins often called p85 proteins. Through the interaction with the SH2-containing adaptor subunits, Class IA PI3K catalytic subunits are linked to tyrosine kinase signaling pathways.	tmpzr1t_l9r_go_relaxed.owl	1-phosphatidylinositol-4-phosphate kinase, class IA complex|phosphoinositide 3-kinase complex, class IA|class IA PI3K complex|1-phosphatidylinositol-4-phosphate 3-kinase, class IA complex											GO:0035030		cellular_component											owl:Class	
GO:0097651	biolink:NamedThing	phosphatidylinositol 3-kinase complex, class I	A phosphatidylinositol 3-kinase complex that contains a catalytic and a regulatory subunit of a phosphatidylinositol 3-kinase (PI3K) enzyme, plus one or more adaptor proteins. Class I PI3Ks phosphorylate phosphatidylinositol [PI], phosphatidylinositol-4-phosphate [PI(4)P] and phosphatidylinositol-4,5-bisphosphate [PI(4,5)P2], and are divided into subclasses A and B according to the type of adaptor subunit with which they associate. The class I PI3K subfamily of genes comprises members in vertebrates, worm and fly, but none in yeast.	tmpzr1t_l9r_go_relaxed.owl	class I PI3K complex|class I phosphatidylinositol 3-kinase complex							pr	2014-09-16T11:19:58Z					cellular_component											owl:Class	
GO:0070743	biolink:NamedThing	interleukin-23 complex	A protein complex that is composed of an interleukin-23 alpha (p19, product of the IL23A gene) and an interleukin-12 beta (p40, product of the IL12B gene) subunit and is secreted into the extracellular space.	tmpzr1t_l9r_go_relaxed.owl	p19|IL12B|p40|IL-23 complex|IL23A					Note that this heterodimeric cytokine utilizes the same beta subunit as IL-12.		mah	2009-06-23T01:06:02Z					cellular_component											owl:Class	
GO:0036373	biolink:NamedThing	L-fucose mutarotase activity	Catalysis of the reaction: alpha-L-fucose = beta-L-fucose.	tmpzr1t_l9r_go_relaxed.owl	type-2 mutarotase activity|alpha-L-fucose 1-epimerase activity|fucose 1-epimerase activity				RHEA:25580|EC:5.1.3.29|MetaCyc:RXN0-5298			bf	2013-05-07T09:51:06Z					molecular_function											owl:Class	
GO:1905178	biolink:NamedThing	regulation of cardiac muscle tissue regeneration	Any process that modulates the frequency, rate or extent of cardiac muscle tissue regeneration.	tmpzr1t_l9r_go_relaxed.owl								rph	2016-05-05T11:30:48Z					biological_process											owl:Class	
GO:0070950	biolink:NamedThing	regulation of neutrophil mediated killing of bacterium	Any process that modulates the rate, frequency or extent of neutrophil mediated killing of a bacterium, the directed killing of a bacterium by a neutrophil.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-10-01T02:14:36Z					biological_process											owl:Class	
GO:0090538	biolink:NamedThing	peptide pheromone secretion	The regulated release of a peptide pheromone from a cell.	tmpzr1t_l9r_go_relaxed.owl								tb	2013-02-11T15:38:29Z					biological_process											owl:Class	
GO:0030072	biolink:NamedThing	peptide hormone secretion	The regulated release of a peptide hormone from a cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:2000375	biolink:NamedThing	negative regulation of oxygen metabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of oxygen metabolic process.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of diatomic oxygen metabolic process|negative regulation of oxygen metabolism							mah	2011-02-11T02:03:44Z					biological_process											owl:Class	
GO:0031801	biolink:NamedThing	type 4 metabotropic glutamate receptor binding	Binding to a type 4 metabotropic glutamate receptor.	tmpzr1t_l9r_go_relaxed.owl	type 4 metabotropic glutamate receptor ligand													molecular_function											owl:Class	
GO:1900101	biolink:NamedThing	regulation of endoplasmic reticulum unfolded protein response	Any process that modulates the frequency, rate or extent of endoplasmic reticulum unfolded protein response.	tmpzr1t_l9r_go_relaxed.owl	regulation of SREBP-mediated signalling pathway|regulation of erUPR|regulation of ER unfolded protein response							ppm	2012-02-15T11:15:27Z					biological_process											owl:Class	
GO:1905897	biolink:NamedThing	regulation of response to endoplasmic reticulum stress	Any process that modulates the frequency, rate or extent of response to endoplasmic reticulum stress.	tmpzr1t_l9r_go_relaxed.owl	regulation of cellular response to endoplasmic reticulum stress|regulation of response to ER stress|regulation of ER stress response							bc	2017-02-01T11:42:55Z					biological_process											owl:Class	
GO:0070800	biolink:NamedThing	negative regulation of conidiophore stalk development	Any process that stops, prevents, or reduces the frequency, rate or extent of conidiophore stalk development, a process that leads to the formation of a conidiophore stalk. The conidiophore stalk is part of a specialized hypha that extends aerially from the growth substrate and supports structures from which conidia, or asexual spores, develop.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-07-08T04:10:42Z					biological_process											owl:Class	
GO:0102772	biolink:NamedThing	sphingolipid long-chain base 4-hydroxylase activity	Catalysis of the reaction: O2 + H+ + a dihydroceramide + NAD(P)H = H2O + a phytoceramide + NAD(P).	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-7797									molecular_function											owl:Class	
GO:1901271	biolink:NamedThing	lipooligosaccharide biosynthetic process	The chemical reactions and pathways resulting in the formation of lipooligosaccharide.	tmpzr1t_l9r_go_relaxed.owl	lipooligosaccharide formation|lipooligosaccharide synthesis|lipooligosaccharide anabolism|lipooligosaccharide biosynthesis							yaf	2012-08-17T14:31:55Z					biological_process											owl:Class	
GO:0090006	biolink:NamedThing	regulation of linear element assembly	Any process that modulates the rate, frequency or extent of linear element assembly. Linear element assembly is the cell cycle process in which a proteinaceous scaffold, related to the synaptonemal complex, is assembled in association with S. pombe chromosomes during meiotic prophase.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-07-17T01:05:13Z					biological_process											owl:Class	
GO:0060629	biolink:NamedThing	regulation of homologous chromosome segregation	Any process that modulates the rate, frequency, or extent of homologous chromosome segregation, the cell cycle process in which replicated homologous chromosomes are organized and then physically separated and apportioned to two sets during the first division of the meiotic cell cycle. Each replicated chromosome, composed of two sister chromatids, aligns at the cell equator, paired with its homologous partner; this pairing off, referred to as synapsis, permits genetic recombination. One homolog (both sister chromatids) of each morphologic type goes into each of the resulting chromosome sets.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-05-18T02:41:02Z					biological_process											owl:Class	
GO:0080090	biolink:NamedThing	regulation of primary metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism involving those compounds formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism.	tmpzr1t_l9r_go_relaxed.owl								dhl	2009-04-22T04:30:52Z					biological_process											owl:Class	
GO:0019222	biolink:NamedThing	regulation of metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism.	tmpzr1t_l9r_go_relaxed.owl	regulation of metabolism|regulation of organismal metabolic process|regulation of multicellular organismal metabolic process											GO:0044246		biological_process											owl:Class	
GO:0006529	biolink:NamedThing	asparagine biosynthetic process	The chemical reactions and pathways resulting in the formation of asparagine, 2-amino-3-carbamoylpropanoic acid.	tmpzr1t_l9r_go_relaxed.owl	asparagine biosynthesis|asparagine synthesis|asparagine anabolism|asparagine formation													biological_process											owl:Class	
GO:0006528	biolink:NamedThing	asparagine metabolic process	The chemical reactions and pathways involving asparagine, 2-amino-3-carbamoylpropanoic acid.	tmpzr1t_l9r_go_relaxed.owl	asparagine metabolism				MetaCyc:ASPARAGINESYN-PWY									biological_process											owl:Class	
GO:0070240	biolink:NamedThing	negative regulation of activated T cell autonomous cell death	Any process that stops, prevents, or reduces the frequency, rate or extent of activated T cell autonomous cell death.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of activated T cell apoptosis|negative regulation of activated cell autonomous cell death|inhibition of activated T cell autonomous cell death|down-regulation of activated T cell autonomous cell death|negative regulation of activated T-cell autonomous cell death|negative regulation of ACAD|downregulation of activated T cell autonomous cell death|negative regulation of activated T-lymphocyte autonomous cell death|down regulation of activated T cell autonomous cell death|negative regulation of activated T lymphocyte autonomous cell death													biological_process											owl:Class	
GO:0015529	biolink:NamedThing	raffinose:proton symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: raffinose(out) + H+(out) = raffinose(in) + H+(in).	tmpzr1t_l9r_go_relaxed.owl	raffinose:hydrogen symporter activity													molecular_function											owl:Class	
GO:0005351	biolink:NamedThing	carbohydrate:proton symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: carbohydrate(out) + H+(out) = carbohydrate(in) + H+(in).	tmpzr1t_l9r_go_relaxed.owl	proton:sugar symporter activity|cation/sugar symporter activity|lactose/glucose efflux transporter activity|sugar:proton symporter activity|sugar efflux transmembrane transporter activity|sugar:hydrogen ion symporter activity|hydrogen:sugar transporter activity|hydrogen:sugar symporter activity|sugar:hydrogen symporter activity|sugar transporter|sugar porter activity				TC:2.A.1.1							GO:0005403|GO:0015542		molecular_function											owl:Class	
GO:0047808	biolink:NamedThing	D(-)-tartrate dehydratase activity	Catalysis of the reaction: D-tartrate = H(2)O + oxaloacetate.	tmpzr1t_l9r_go_relaxed.owl	D-tartrate dehydratase activity|(S,S)-tartrate hydro-lyase activity|(S,S)-tartrate hydro-lyase (oxaloacetate-forming)				MetaCyc:D--TARTRATE-DEHYDRATASE-RXN|RHEA:18289|EC:4.2.1.81|KEGG_REACTION:R00340									molecular_function											owl:Class	
GO:0015558	biolink:NamedThing	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity	Enables the transfer of p-aminobenzoyl-glutamate from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters. p-aminobenzoyl-glutamate is the anion of p-aminobenzoyl-glutamic acid.	tmpzr1t_l9r_go_relaxed.owl	p-aminobenzoyl-glutamate transmembrane transporter activity|p-aminobenzoyl-glutamate transporter activity|p-aminobenzoyl-glutamate uptake permease activity|p-aminobenzoyl-glutamate uptake transmembrane transporter activity											GO:0015569		molecular_function											owl:Class	
GO:0047853	biolink:NamedThing	difructose-anhydride synthase activity	Catalysis of the reaction: H2O + bis-D-fructose 2',1:2,1'-dianhydride = inulobiose.	tmpzr1t_l9r_go_relaxed.owl	bis-D-fructose 2',1:2,1'-dianhydride fructohydrolase activity|inulobiose hydrolase activity				RHEA:15041|MetaCyc:DIFRUCTOSE-ANHYDRIDE-SYNTHASE-RXN|EC:3.2.1.134									molecular_function											owl:Class	
GO:0032352	biolink:NamedThing	positive regulation of hormone metabolic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving any hormone.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of hormone metabolic process|positive regulation of hormone metabolism|activation of hormone metabolic process|upregulation of hormone metabolic process|up regulation of hormone metabolic process|stimulation of hormone metabolic process													biological_process											owl:Class	
GO:1900503	biolink:NamedThing	regulation of cellulosome assembly	Any process that modulates the frequency, rate or extent of cellulosome assembly.	tmpzr1t_l9r_go_relaxed.owl								tt	2012-05-02T03:58:15Z					biological_process											owl:Class	
GO:1901854	biolink:NamedThing	5,6,7,8-tetrahydrosarcinapterin catabolic process	The chemical reactions and pathways resulting in the breakdown of 5,6,7,8-tetrahydrosarcinapterin.	tmpzr1t_l9r_go_relaxed.owl	5,6,7,8-tetrahydrosarcinapterin breakdown|5,6,7,8-tetrahydrosarcinapterin degradation|5,6,7,8-tetrahydrosarcinapterin catabolism							yaf	2013-01-28T11:48:01Z					biological_process											owl:Class	
GO:0072352	biolink:NamedThing	tricarboxylic acid catabolic process	The chemical reactions and pathways resulting in the breakdown of dicarboxylic acids, any organic acid containing three carboxyl (-COOH) groups.	tmpzr1t_l9r_go_relaxed.owl	tricarboxylic acid catabolism|tricarboxylic acid breakdown|tricarboxylic acid degradation|tricarboxylate catabolic process|tricarboxylate catabolism							mah	2010-11-11T05:11:24Z					biological_process											owl:Class	
GO:0007364	biolink:NamedThing	establishment of terminal gap gene boundary	Specification of the borders of terminal gap gene expression mediated largely by the effects of other gap genes.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0048859	biolink:NamedThing	formation of anatomical boundary	The process in which the limits of an anatomical structure are generated. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0051945	biolink:NamedThing	negative regulation of catecholamine uptake involved in synaptic transmission	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of catecholamine neurotransmitters into a neuron or glial cell.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of catecholamine uptake during transmission of nerve impulse|negative regulation of catecholamine neurotransmitter uptake|negative regulation of catecholamine neurotransmitter reuptake|downregulation of catecholamine uptake during transmission of nerve impulse|negative regulation of catecholamine uptake during transmission of nerve impulse|inhibition of catecholamine uptake during transmission of nerve impulse|down regulation of catecholamine uptake during transmission of nerve impulse													biological_process											owl:Class	
GO:0019392	biolink:NamedThing	glucarate metabolic process	The chemical reactions and pathways involving glucarate, the dianion of glucaric acid, an aldaric acid derived from either glucose or gulose. There are two enantiomers L- and D-glucarate.	tmpzr1t_l9r_go_relaxed.owl	glucarate metabolism											GO:0019581		biological_process											owl:Class	
GO:0043484	biolink:NamedThing	regulation of RNA splicing	Any process that modulates the frequency, rate or extent of RNA splicing, the process of removing sections of the primary RNA transcript to remove sequences not present in the mature form of the RNA and joining the remaining sections to form the mature form of the RNA.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0070710	biolink:NamedThing	RNA uridine deletion	The modification of an RNA molecule by removal of a uridine nucleotide.	tmpzr1t_l9r_go_relaxed.owl	RNA uridine excision|RNA U deletion							mah	2009-06-08T05:12:43Z					biological_process											owl:Class	
GO:0070706	biolink:NamedThing	RNA nucleotide deletion	The modification of an RNA molecule by removal of a single nucleotide.	tmpzr1t_l9r_go_relaxed.owl	RNA nucleotide excision							mah	2009-06-08T04:50:51Z					biological_process											owl:Class	
GO:0002802	biolink:NamedThing	positive regulation of antifungal peptide secretion	Any process that activates or increases the frequency, rate, or extent of antifungal peptide secretion.	tmpzr1t_l9r_go_relaxed.owl	upregulation of antifungal peptide secretion|up-regulation of antifungal peptide secretion|up regulation of antifungal peptide secretion|activation of antifungal peptide secretion|stimulation of antifungal peptide secretion													biological_process											owl:Class	
GO:0002800	biolink:NamedThing	regulation of antifungal peptide secretion	Any process that modulates the frequency, rate, or extent of antifungal peptide secretion.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0002108	biolink:NamedThing	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, LSU-rRNA,5S)	Any process involved in the maturation of a precursor Large SubUnit (LSU) ribosomal RNA (rRNA) molecule into a mature LSU-rRNA molecule from the pre-rRNA molecule originally produced as a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, Large Subunit (LSU) the 5S rRNA in that order from 5' to 3' along the primary transcript.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0000470	biolink:NamedThing	maturation of LSU-rRNA	Any process involved in the maturation of a precursor Large SubUnit (LSU) ribosomal RNA (rRNA) molecule into a mature LSU-rRNA molecule.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1900178	biolink:NamedThing	negative regulation of aflatoxin biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of aflatoxin biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	downregulation of aflatoxin anabolism|down regulation of aflatoxin biosynthesis|downregulation of aflatoxin biosynthetic process|down-regulation of aflatoxin biosynthetic process|negative regulation of aflatoxin biosynthesis|downregulation of aflatoxin formation|down regulation of aflatoxin anabolism|inhibition of aflatoxin biosynthesis|down-regulation of aflatoxin synthesis|inhibition of aflatoxin anabolism|inhibition of aflatoxin synthesis|down regulation of aflatoxin formation|inhibition of aflatoxin formation|downregulation of aflatoxin synthesis|downregulation of aflatoxin biosynthesis|inhibition of aflatoxin biosynthetic process|down-regulation of aflatoxin anabolism|down regulation of aflatoxin synthesis|down-regulation of aflatoxin formation|negative regulation of aflatoxin synthesis|down-regulation of aflatoxin biosynthesis|negative regulation of aflatoxin formation|negative regulation of aflatoxin anabolism|down regulation of aflatoxin biosynthetic process							di	2012-03-09T11:23:42Z					biological_process											owl:Class	
GO:0002016	biolink:NamedThing	regulation of blood volume by renin-angiotensin	The process in which the renin-angiotensin system controls the rate of fluid intake and output into the blood.	tmpzr1t_l9r_go_relaxed.owl	renin-angiotensin control of body fluid levels|renin-angiotensin regulation of blood volume													biological_process											owl:Class	
GO:0051296	biolink:NamedThing	establishment of meiotic spindle orientation	Any process that set the alignment of meiotic spindle relative to other cellular structures.	tmpzr1t_l9r_go_relaxed.owl	orienting of meiotic spindle|establishment of spindle orientation involved in meiotic cell cycle|meiotic spindle orientation|establishment of spindle orientation during meiosis													biological_process											owl:Class	
GO:0051294	biolink:NamedThing	establishment of spindle orientation	Any process that set the alignment of spindle relative to other cellular structures.	tmpzr1t_l9r_go_relaxed.owl	orienting of spindle|spindle orientation													biological_process											owl:Class	
GO:0018016	biolink:NamedThing	N-terminal peptidyl-proline dimethylation	The methylation of the N-terminal proline of proteins to form the derivative N,N-dimethyl-L-proline.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0066									biological_process											owl:Class	
GO:0035568	biolink:NamedThing	N-terminal peptidyl-proline methylation	The methylation of the N-terminal proline of proteins.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0419			bf	2010-08-06T01:52:43Z					biological_process											owl:Class	
GO:0019823	biolink:NamedThing	P5 peroxisome	A subform of peroxisome that corresponds to an intermediate in a peroxisome assembly pathway, which operates by conversion of peroxisomal subforms in the direction P1, P2 -> P3 -> P4 -> P5 -> P6. P5 peroxisomes are distinguished from the other subforms on the bases of buoyant density and protein content.	tmpzr1t_l9r_go_relaxed.owl	peroxisome vesicle					Note that this peroxisome assembly pathway is described in the yeast Yarrowia lipolytica. See also the cellular component terms 'P1 peroxisome ; GO:0019819', 'P2 peroxisome ; GO:0019820', 'P3 peroxisome ; GO:0019821', 'P4 peroxisome ; GO:0019822', and 'P6 peroxisome ; GO:0019824'.								cellular_component											owl:Class	
GO:0060052	biolink:NamedThing	neurofilament cytoskeleton organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising neurofilaments and their associated proteins.	tmpzr1t_l9r_go_relaxed.owl	neurofilament cytoskeleton organisation|neurofilament cytoskeleton organization and biogenesis													biological_process											owl:Class	
GO:0019852	biolink:NamedThing	L-ascorbic acid metabolic process	The chemical reactions and pathways involving L-ascorbic acid, (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate; L-ascorbic acid is vitamin C and has co-factor and anti-oxidant activities in many species.	tmpzr1t_l9r_go_relaxed.owl	L-ascorbic acid metabolism|vitamin C metabolism|ascorbate metabolic process|vitamin C metabolic process|ascorbate metabolism													biological_process											owl:Class	
GO:1903078	biolink:NamedThing	positive regulation of protein localization to plasma membrane	Any process that activates or increases the frequency, rate or extent of protein localization to plasma membrane.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of protein localization in plasma membrane|up regulation of protein-plasma membrane targeting|up regulation of protein localization to plasma membrane|up-regulation of protein localization in plasma membrane|up-regulation of protein-plasma membrane targeting|positive regulation of protein-plasma membrane targeting|activation of protein targeting to plasma membrane|upregulation of protein-plasma membrane targeting|activation of protein localization to plasma membrane|activation of protein localisation in plasma membrane|up regulation of protein localization in plasma membrane|up-regulation of protein localization to plasma membrane|positive regulation of protein targeting to plasma membrane|upregulation of protein localisation in plasma membrane|activation of protein-plasma membrane targeting|up regulation of protein targeting to plasma membrane|upregulation of protein localization to plasma membrane|upregulation of protein targeting to plasma membrane|up regulation of protein localisation in plasma membrane|positive regulation of protein localisation in plasma membrane|up-regulation of protein localisation in plasma membrane|positive regulation of establishment of protein localization to plasma membrane|positive regulation of establishment of protein localisation in plasma membrane|up-regulation of protein targeting to plasma membrane|activation of protein localization in plasma membrane|upregulation of protein localization in plasma membrane							tb	2009-07-10T10:34:17Z			GO:1905965|GO:0090004		biological_process											owl:Class	
GO:1905763	biolink:NamedThing	MTREC complex binding	Binding to a MTREC complex.	tmpzr1t_l9r_go_relaxed.owl	PAXT complex binding|Mtl1-Red1 core complex binding|NURS complex binding	https://github.com/geneontology/go-ontology/issues/21207						mah	2016-12-15T15:49:02Z					molecular_function											owl:Class	
GO:0015686	biolink:NamedThing	ferric triacetylfusarinine C import into cell	The directed movement of ferric triacetylfusarinine C into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	ferric triacetylfusarinine C transport													biological_process											owl:Class	
GO:0033214	biolink:NamedThing	siderophore-dependent iron import into cell	A process in which iron (Fe3+) is solubilized by ferric iron-specific chelators, known as siderophores, excreted by a cell; the iron-siderophore complex is then transported into the cell by specific cell surface receptors.	tmpzr1t_l9r_go_relaxed.owl	iron chelate transport|iron assimilation by capture and transport|iron assimilation by chelation and transport											GO:0015688|GO:0033213		biological_process											owl:Class	
GO:1900663	biolink:NamedThing	positive regulation of emericellamide A biosynthetic process	Any process that activates or increases the frequency, rate or extent of emericellamide A biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	activation of emericellamide A formation|activation of emericellamide A synthesis|up-regulation of emericellamide A formation|up regulation of emericellamide A formation|up-regulation of emericellamide A biosynthetic process|upregulation of emericellamide A synthesis|positive regulation of emericellamide A biosynthesis|up-regulation of emericellamide A anabolism|upregulation of emericellamide A biosynthetic process|up regulation of emericellamide A anabolism|positive regulation of emericellamide A anabolism|activation of emericellamide A biosynthesis|positive regulation of emericellamide A synthesis|upregulation of emericellamide A formation|activation of emericellamide A biosynthetic process|upregulation of emericellamide A biosynthesis|up regulation of emericellamide A biosynthesis|up-regulation of emericellamide A biosynthesis|up-regulation of emericellamide A synthesis|positive regulation of emericellamide A formation|upregulation of emericellamide A anabolism|up regulation of emericellamide A synthesis|up regulation of emericellamide A biosynthetic process|activation of emericellamide A anabolism							di	2012-05-22T04:13:36Z					biological_process											owl:Class	
GO:1900661	biolink:NamedThing	regulation of emericellamide A biosynthetic process	Any process that modulates the frequency, rate or extent of emericellamide A biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of emericellamide A formation|regulation of emericellamide A biosynthesis|regulation of emericellamide A anabolism|regulation of emericellamide A synthesis							di	2012-05-22T04:13:07Z					biological_process											owl:Class	
GO:1902460	biolink:NamedThing	regulation of mesenchymal stem cell proliferation	Any process that modulates the frequency, rate or extent of mesenchymal stem cell proliferation.	tmpzr1t_l9r_go_relaxed.owl	regulation of MSC proliferation							pm	2013-10-22T10:01:00Z					biological_process											owl:Class	
GO:0047997	biolink:NamedThing	hydroxypyruvate decarboxylase activity	Catalysis of the reaction: 3-hydroxypyruvate + H(+) = CO(2) + glycolaldehyde.	tmpzr1t_l9r_go_relaxed.owl	hydroxypyruvate carboxy-lyase (glycolaldehyde-forming)|hydroxypyruvate carboxy-lyase activity				MetaCyc:HYDROXYPYRUVATE-DECARBOXYLASE-RXN|RHEA:20561|EC:4.1.1.40|KEGG_REACTION:R01393									molecular_function											owl:Class	
GO:2000708	biolink:NamedThing	myosin filament organization involved in cytokinetic actomyosin contractile ring assembly	A myosin filament organization process that contributes to actomyosin contractile ring assembly during cytokinesis.	tmpzr1t_l9r_go_relaxed.owl	myosin filament organization of constriction ring assembly|myosin filament organization of cytokinesis, actomyosin contractile ring assembly|myosin filament assembly or disassembly of cytokinesis, actomyosin contractile ring assembly|myosin filament organization of cytokinesis, contractile ring assembly|myosin filament assembly or disassembly of cytokinesis, actomyosin ring biosynthesis|myosin polymerization or depolymerization of cytokinesis, actomyosin ring formation|myosin polymerization or depolymerization of cytokinesis, actomyosin ring biosynthesis|myosin filament assembly or disassembly of constriction ring assembly|myosin filament assembly or disassembly of cytokinesis, contractile ring assembly|myosin filament assembly or disassembly of cytokinesis, actomyosin ring formation|myosin filament organization of cytokinesis, actomyosin ring biosynthesis|myosin polymerization or depolymerization of constriction ring assembly|myosin filament organisation involved in cytokinetic actomyosin contractile ring assembly|myosin polymerization or depolymerization of cytokinesis, actomyosin contractile ring assembly|myosin filament assembly or disassembly of contractile ring assembly|myosin filament organization of cytokinesis, actomyosin contractile ring formation|myosin filament assembly or disassembly of cytokinesis, actomyosin contractile ring formation|myosin polymerization or depolymerization of contractile ring assembly|myosin filament organization of contractile ring assembly|myosin filament organization of cytokinesis, actomyosin ring formation|myosin polymerization or depolymerization of cytokinesis, contractile ring assembly|myosin polymerization or depolymerization of cytokinesis, actomyosin contractile ring formation							mah	2011-06-01T12:33:56Z					biological_process											owl:Class	
GO:0031033	biolink:NamedThing	myosin filament organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a filament composed of myosin molecules.	tmpzr1t_l9r_go_relaxed.owl	myosin filament assembly or disassembly|myosin polymerization or depolymerization|myosin filament organisation					Note that this term is a child of 'actin cytoskeleton organization and biogenesis ; GO:0030036' because the actin cytoskeleton is defined as actin filaments and associated proteins; myosin structures are sufficiently closely associated with actin filaments to be included with the actin cytoskeleton.								biological_process											owl:Class	
GO:0018115	biolink:NamedThing	peptidyl-S-diphytanylglycerol diether-L-cysteine biosynthetic process from peptidyl-cysteine	The modification of cysteine to form peptidyl-S-diphytanylglycerol diether-L-cysteine.	tmpzr1t_l9r_go_relaxed.owl	peptidyl-S-diphytanylglycerol diether-L-cysteine anabolism from peptidyl-cysteine|peptidyl-S-diphytanylglycerol diether-L-cysteine formation from peptidyl-cysteine|peptidyl-S-diphytanylglycerol diether-L-cysteine synthesis from peptidyl-cysteine				RESID:AA0223									biological_process											owl:Class	
GO:1903071	biolink:NamedThing	positive regulation of ER-associated ubiquitin-dependent protein catabolic process	Any process that activates or increases the frequency, rate or extent of ER-associated ubiquitin-dependent protein catabolic process.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of ER-associated protein breakdown|activation of endoplasmic reticulum-associated protein catabolism|positive regulation of ER-associated protein degradation|activation of ERAD|positive regulation of ER-associated protein breakdown|upregulation of endoplasmic reticulum-associated protein catabolic process|upregulation of ERAD|positive regulation of endoplasmic reticulum-associated protein catabolism|up-regulation of ER-associated protein degradation|positive regulation of ER-associated protein catabolism|upregulation of ER-associated protein catabolic process|up regulation of ER-associated protein catabolic process|activation of ER-associated protein catabolic process|positive regulation of ERAD|up regulation of ER-associated ubiquitin-dependent protein catabolic process|upregulation of ER-associated protein degradation|positive regulation of ER-associated protein catabolic process|up-regulation of ER-associated protein catabolism|upregulation of ER-associated ubiquitin-dependent protein catabolic process|up-regulation of ER-associated protein catabolic process|activation of ER-associated protein catabolism|up regulation of ER-associated protein catabolism|up regulation of endoplasmic reticulum-associated protein catabolism|up-regulation of endoplasmic reticulum-associated protein catabolism|up regulation of ER-associated protein degradation|up regulation of endoplasmic reticulum-associated protein catabolic process|positive regulation of endoplasmic reticulum-associated protein catabolic process|activation of ER-associated protein breakdown|upregulation of ER-associated protein catabolism|up-regulation of endoplasmic reticulum-associated protein catabolic process|upregulation of endoplasmic reticulum-associated protein catabolism|upregulation of ER-associated protein breakdown|activation of ER-associated ubiquitin-dependent protein catabolic process|up-regulation of ERAD|activation of endoplasmic reticulum-associated protein catabolic process|up regulation of ER-associated protein breakdown|up regulation of ERAD|up-regulation of ER-associated ubiquitin-dependent protein catabolic process|activation of ER-associated protein degradation							rph	2014-05-28T17:54:04Z					biological_process											owl:Class	
GO:1904043	biolink:NamedThing	positive regulation of cystathionine beta-synthase activity	Any process that activates or increases the frequency, rate or extent of cystathionine beta-synthase activity.	tmpzr1t_l9r_go_relaxed.owl	upregulation of serine sulfhydrase activity|up-regulation of L-serine hydro-lyase (adding homocysteine; L-cystathionine-forming)|up regulation of serine sulfhydrase activity|up regulation of methylcysteine synthase activity|activation of serine sulfhydrylase activity|upregulation of serine sulfhydrylase activity|up-regulation of L-serine hydro-lyase (adding homocysteine)|upregulation of L-serine hydro-lyase (adding homocysteine; L-cystathionine-forming)|up regulation of L-serine hydro-lyase (adding homocysteine; L-cystathionine-forming)|activation of serine sulfhydrase activity|up regulation of cystathionine beta-synthase activity|up regulation of L-serine hydro-lyase (adding homocysteine)|upregulation of cystathionine beta-synthase activity|up-regulation of beta-thionase activity|up-regulation of cystathionine beta-synthase activity|upregulation of beta-thionase activity|positive regulation of methylcysteine synthase activity|up regulation of serine sulfhydrylase activity|up-regulation of methylcysteine synthase activity|positive regulation of serine sulfhydrase activity|activation of L-serine hydro-lyase (adding homocysteine)|positive regulation of serine sulfhydrylase activity|positive regulation of beta-thionase activity|activation of cystathionine beta-synthase activity|activation of beta-thionase activity|positive regulation of L-serine hydro-lyase (adding homocysteine; L-cystathionine-forming)|activation of L-serine hydro-lyase (adding homocysteine; L-cystathionine-forming)|activation of methylcysteine synthase activity|upregulation of L-serine hydro-lyase (adding homocysteine)|up-regulation of serine sulfhydrylase activity|up regulation of beta-thionase activity|upregulation of methylcysteine synthase activity|positive regulation of L-serine hydro-lyase (adding homocysteine)|up-regulation of serine sulfhydrase activity							hal	2015-03-16T15:52:53Z					biological_process											owl:Class	
GO:1904041	biolink:NamedThing	regulation of cystathionine beta-synthase activity	Any process that modulates the frequency, rate or extent of cystathionine beta-synthase activity.	tmpzr1t_l9r_go_relaxed.owl	regulation of L-serine hydro-lyase (adding homocysteine; L-cystathionine-forming)|regulation of serine sulfhydrase activity|regulation of methylcysteine synthase activity|regulation of beta-thionase activity|regulation of L-serine hydro-lyase (adding homocysteine)|regulation of serine sulfhydrylase activity							hal	2015-03-16T15:52:41Z					biological_process											owl:Class	
GO:0034204	biolink:NamedThing	lipid translocation	The translocation, or flipping, of lipid molecules from one monolayer of a membrane bilayer to the opposite monolayer.	tmpzr1t_l9r_go_relaxed.owl	intramembrane lipid transfer													biological_process											owl:Class	
GO:1902919	biolink:NamedThing	poly(5-hydroxyvalerate) biosynthetic process	The chemical reactions and pathways resulting in the formation of poly(5-hydroxyvalerate).	tmpzr1t_l9r_go_relaxed.owl	poly(5-hydroxyvalerate) formation|poly(5-hydroxyvalerate) synthesis|poly(5-hydroxyvalerate) anabolism|poly(5-hydroxyvalerate) biosynthesis							tt	2014-04-21T18:47:12Z					biological_process											owl:Class	
GO:1902918	biolink:NamedThing	poly(5-hydroxyvalerate) metabolic process	The chemical reactions and pathways involving poly(5-hydroxyvalerate).	tmpzr1t_l9r_go_relaxed.owl	poly(5-hydroxyvalerate) metabolism							tt	2014-04-21T18:47:06Z					biological_process											owl:Class	
GO:0005542	biolink:NamedThing	folic acid binding	Binding to folic acid, pteroylglutamic acid. Folic acid is widely distributed as a member of the vitamin B complex and is essential for the synthesis of purine and pyrimidines.	tmpzr1t_l9r_go_relaxed.owl	vitamin M binding|folate binding|vitamin B9 binding													molecular_function											owl:Class	
GO:0000981	biolink:NamedThing	DNA-binding transcription factor activity, RNA polymerase II-specific	A DNA-binding transcription factor activity that modulates the transcription of specific gene sets transcribed by RNA polymerase II.	tmpzr1t_l9r_go_relaxed.owl	zinc ion regulated core promoter proximal region sequence-specific DNA binding RNA polymerase II transcription factor activity|RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity|RNA polymerase II transcription factor activity, zinc ion regulated proximal promoter sequence-specific DNA binding|transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding|RNA polymerase II transcription factor activity, zinc ion regulated core promoter proximal region sequence-specific DNA binding|metal ion regulated sequence-specific DNA binding RNA polymerase II transcription factor activity|RNA polymerase II transcription factor activity, metal ion regulated core promoter proximal region sequence-specific binding|copper ion regulated core promoter proximal region sequence-specific DNA binding RNA polymerase II transcription factor activity|transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding|RNA polymerase II transcription factor activity, copper ion regulated proximal promoter sequence-specific DNA binding|sequence-specific transcription regulatory region DNA binding RNA polymerase II transcription factor recruiting transcription factor activity|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity|RNA polymerase II transcription factor activity, metal ion regulated proximal promoter sequence-specific DNA binding|transcription factor|RNA polymerase II transcription factor activity, sequence-specific transcription regulatory region DNA binding|RNA polymerase II transcription factor activity, sequence-specific DNA binding|sequence-specific DNA binding RNA polymerase II transcription factor activity|sequence-specific distal enhancer binding RNA polymerase II transcription factor activity|metal ion regulated core promoter proximal region sequence-specific DNA binding RNA polymerase II transcription factor activity|transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding|RNA polymerase II transcription factor activity, metal ion regulated sequence-specific DNA binding|RNA polymerase II transcription factor activity, copper ion regulated core promoter proximal region sequence-specific binding	https://github.com/geneontology/go-ontology/issues/16152|https://github.com/geneontology/go-ontology/issues/15530|https://github.com/geneontology/go-ontology/issues/16131				For usage guidance, see comment in GO:0003700 ; DNA-binding transcription factor activity.		krc	2010-08-10T02:37:21Z			GO:0003705|GO:0000982|GO:0001200|GO:0001203|GO:0001133|GO:0001202|GO:0001201		molecular_function											owl:Class	
GO:0008068	biolink:NamedThing	extracellularly glutamate-gated chloride channel activity	Enables the transmembrane transfer of a chloride ion by a channel that opens when  glutamate is bound by the channel complex or one of its constituent parts on the extracellular side of the plasma membrane.	tmpzr1t_l9r_go_relaxed.owl	extracellular-glutamate-gated chloride channel activity					Note that this term represents an activity and not a gene product. Consider also annotating to the molecular function term 'glutamate receptor activity ; GO:0008066'.								molecular_function											owl:Class	
GO:0005234	biolink:NamedThing	extracellularly glutamate-gated ion channel activity	Enables the transmembrane transfer of an ion by a channel that opens when glutamate is  bound by the channel complex or one of its constituent parts on the extracellular side of the plasma membrane.	tmpzr1t_l9r_go_relaxed.owl	extracellular-glutamate-gated ion channel activity					Note that this term represents an activity and not a gene product. Consider also annotating to the molecular function term 'glutamate receptor activity ; GO:0008066'.								molecular_function											owl:Class	
GO:0002895	biolink:NamedThing	regulation of central B cell tolerance induction	Any process that modulates the frequency, rate, or extent of central B cell tolerance induction.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0042439	biolink:NamedThing	ethanolamine-containing compound metabolic process	The chemical reactions and pathways involving ethanolamine (2-aminoethanol) and compounds derived from it.	tmpzr1t_l9r_go_relaxed.owl	ethanolamine-containing compound metabolism|ethanolamine and derivative metabolic process|ethanolamine and derivative metabolism													biological_process											owl:Class	
GO:0006576	biolink:NamedThing	cellular biogenic amine metabolic process	The chemical reactions and pathways occurring at the level of individual cells involving any of a group of naturally occurring, biologically active amines, such as norepinephrine, histamine, and serotonin, many of which act as neurotransmitters.	tmpzr1t_l9r_go_relaxed.owl	biogenic amine metabolism													biological_process											owl:Class	
GO:0045037	biolink:NamedThing	protein import into chloroplast stroma	The targeting and import of proteins into the chloroplast stroma. Import depends on ATP hydrolysis catalyzed by stromal chaperones. Chloroplast stromal proteins, such as the S subunit of rubisco, have a N-terminal stromal-import sequence of about 44 amino acids which is cleaved from the protein precursor after import.	tmpzr1t_l9r_go_relaxed.owl	protein transport into chloroplast stroma|chloroplast stroma protein import													biological_process											owl:Class	
GO:0106069	biolink:NamedThing	synapsis initiation complex	A SUMO-E3 ligase complex capable of promoting synapsis, the meiotic cell cycle process where side by side pairing and physical juxtaposition of homologous chromosomes is created during meiotic prophase.	tmpzr1t_l9r_go_relaxed.owl								hjd	2017-11-22T18:50:26Z					cellular_component											owl:Class	
GO:0034557	biolink:NamedThing	2-hydroxylaminobenzoate reductase activity	Catalysis of the reaction: 2-hydroxylaminobenzoate + NAD(P)H = anthranilate + NAD(P)+ + H2O.	tmpzr1t_l9r_go_relaxed.owl	o-hydroxylaminobenzoate nitroreductase activity				UM-BBD_reactionID:r0850|MetaCyc:RXN-8848									molecular_function											owl:Class	
GO:0018339	biolink:NamedThing	peptidyl-L-beta-methylthioaspartic acid biosynthetic process from peptidyl-aspartic acid	The modification of peptidyl-aspartic acid to form peptidyl-L-beta-methylthioaspartic acid, typical of bacterial ribosomal protein S12.	tmpzr1t_l9r_go_relaxed.owl	peptidyl-L-beta-methylthioaspartic acid synthesis from peptidyl-aspartic acid|peptidyl-aspartic acid methylthiolation|peptidyl-L-beta-methylthioaspartic acid formation from peptidyl-aspartic acid|peptidyl-L-beta-methylthioaspartic acid anabolism from peptidyl-aspartic acid				RESID:AA0232									biological_process											owl:Class	
GO:2000355	biolink:NamedThing	negative regulation of ovarian follicle development	Any process that stops, prevents or reduces the frequency, rate or extent of ovarian follicle development.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of follicular phase							yaf	2011-02-03T02:01:32Z					biological_process											owl:Class	
GO:0032616	biolink:NamedThing	interleukin-13 production	The appearance of interleukin-13 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	tmpzr1t_l9r_go_relaxed.owl	interleukin-13 secretion|interleukin-13 biosynthetic process|IL-13 production											GO:0072611|GO:0042231		biological_process											owl:Class	
GO:0030644	biolink:NamedThing	cellular chloride ion homeostasis	Any process involved in the maintenance of an internal steady state of chloride ions at the level of a cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0055064	biolink:NamedThing	chloride ion homeostasis	Any process involved in the maintenance of an internal steady state of chloride ions within an organism or cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0050860	biolink:NamedThing	negative regulation of T cell receptor signaling pathway	Any process that stops, prevents, or reduces the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a T cell.	tmpzr1t_l9r_go_relaxed.owl	downregulation of T cell receptor signaling pathway|negative regulation of T cell receptor signalling pathway|down-regulation of T cell receptor signaling pathway|inhibition of T cell receptor signaling pathway|negative regulation of T-lymphocyte receptor signaling pathway|negative regulation of T-lymphocyte receptor signalling pathway|negative regulation of T lymphocyte receptor signaling pathway|negative regulation of TCR signaling pathway|negative regulation of T lymphocyte receptor signalling pathway|negative regulation of T-cell receptor signaling pathway|down regulation of T cell receptor signaling pathway													biological_process											owl:Class	
GO:0035308	biolink:NamedThing	negative regulation of protein dephosphorylation	Any process the stops, prevents, or reduces the frequency, rate or extent of removal of phosphate groups from a protein.	tmpzr1t_l9r_go_relaxed.owl	downregulation of protein amino acid dephosphorylation|inhibition of protein amino acid dephosphorylation|negative regulation of protein amino acid dephosphorylation|down-regulation of protein amino acid dephosphorylation|down regulation of protein amino acid dephosphorylation													biological_process											owl:Class	
GO:0035305	biolink:NamedThing	negative regulation of dephosphorylation	Any process the stops, prevents, or reduces the frequency, rate or extent of removal of phosphate groups from a molecule.	tmpzr1t_l9r_go_relaxed.owl	downregulation of dephosphorylation|down-regulation of dephosphorylation|down regulation of dephosphorylation|inhibition of dephosphorylation													biological_process											owl:Class	
GO:0000500	biolink:NamedThing	RNA polymerase I upstream activating factor complex	A complex required for the transcription of rDNA by RNA polymerase I. In yeast the complex consists of Rrrn5p, Rrn9p, Rrn10p, histones H3 and H4, and Uaf30p.	tmpzr1t_l9r_go_relaxed.owl	RNA polymerase I upstream activation factor complex|UAF													cellular_component											owl:Class	
GO:0000120	biolink:NamedThing	RNA polymerase I transcription regulator complex	A transcription factor complex that acts at a regulatory region of a gene transcribed by RNA polymerase I.	tmpzr1t_l9r_go_relaxed.owl	RNA polymerase I transcription factor complex													cellular_component											owl:Class	
GO:0042310	biolink:NamedThing	vasoconstriction	A decrease in the diameter of blood vessels, especially arteries, due to constriction of smooth muscle cells that line the vessels, and usually causing an increase in blood pressure.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of blood vessel size				Wikipedia:Vasoconstriction							GO:0045908		biological_process											owl:Class	
GO:0045150	biolink:NamedThing	acetoin catabolic process	The chemical reactions and pathways resulting in the breakdown of acetoin, 3-hydroxy-2-butanone.	tmpzr1t_l9r_go_relaxed.owl	acetoin breakdown|acetoin catabolism|acetoin degradation													biological_process											owl:Class	
GO:1990720	biolink:NamedThing	C2 axonemal microtubule	One of two microtubules present in the axonemal central pair. It is distinguishable from the C1 axonemal microtubule (also called C1 tubule) by the presence of differing protein components of the projections.	tmpzr1t_l9r_go_relaxed.owl	C2 tubule							krc	2015-03-27T22:58:40Z					cellular_component											owl:Class	
GO:0005879	biolink:NamedThing	axonemal microtubule	A microtubule in the axoneme of a eukaryotic cilium or flagellum; an axoneme contains nine modified doublet microtubules, which may or may not surround a pair of single microtubules.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0099074	biolink:NamedThing	mitochondrion to lysosome transport	Transport from the mitochondrion to the lysosome, mediated by mitochondrion-derived vesicles.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0099075	biolink:NamedThing	mitochondrion-derived vesicle mediated transport	Transport from the mitochondrion, mediated by mitochondrion derived vesicles.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0044309	biolink:NamedThing	neuron spine	A small membranous protrusion, often ending in a bulbous head and attached to the neuron by a narrow stalk or neck.	tmpzr1t_l9r_go_relaxed.owl	spine				NIF_Subcellular:sao1145756102			jl	2010-02-05T04:25:10Z					cellular_component											owl:Class	
GO:0101019	biolink:NamedThing	nucleolar exosome (RNase complex)	A ribonuclease complex that has 3-prime to 5-prime distributive hydrolytic exoribonuclease activity and in some taxa (e.g. yeast) endoribonuclease activity, producing 5-prime-phosphomonoesters. Participates in a multitude of cellular RNA processing and degradation events preventing nuclear export and/or translation of aberrant RNAs. Restricted to processing linear and circular single-stranded RNAs (ssRNA) only. RNAs with complex secondary structures may have to be unwound or pre-processed by co-factors prior to entering the complex, esp if the 3-prime end is structured.	tmpzr1t_l9r_go_relaxed.owl								bhm						cellular_component											owl:Class	
GO:0000178	biolink:NamedThing	exosome (RNase complex)	A ribonuclease complex that has 3-prime to 5-prime exoribonuclease activity and possibly endoribonuclease activity, producing 5-prime-phosphomonoesters. Participates in a multitude of cellular RNA processing and degradation events preventing nuclear export and/or translation of aberrant RNAs. Restricted to processing linear and circular single-stranded RNAs (ssRNA) only. RNAs with complex secondary structures may have to be unwound or pre-processed by co-factors prior to entering the complex, esp if the 3-prime end is structured.	tmpzr1t_l9r_go_relaxed.owl	exosome multienzyme ribonuclease complex|exosome (ribonucleasease complex)					Note that this term should not be confused with 'exosome' used in the context of vesicles released from multivesicular bodies.								cellular_component											owl:Class	
GO:0039584	biolink:NamedThing	suppression by virus of host protein kinase activity	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host protein kinase activity.	tmpzr1t_l9r_go_relaxed.owl								bf	2012-05-02T03:04:55Z					biological_process											owl:Class	
GO:0071169	biolink:NamedThing	establishment of protein localization to chromatin	The directed movement of a protein to a part of a chromosome that is organized into chromatin.	tmpzr1t_l9r_go_relaxed.owl	establishment of protein localisation to chromatin							mah	2009-11-20T11:52:43Z					biological_process											owl:Class	
GO:0071168	biolink:NamedThing	protein localization to chromatin	Any process in which a protein is transported to, or maintained at, a part of a chromosome that is organized into chromatin.	tmpzr1t_l9r_go_relaxed.owl	protein localisation to chromatin							mah	2009-11-20T11:51:20Z					biological_process											owl:Class	
GO:0008173	biolink:NamedThing	RNA methyltransferase activity	Catalysis of the transfer of a methyl group from a donor to a nucleoside residue in an RNA molecule.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-191784	Note that the methyl donor is usually S-adenosyl-L-methionine, but there is at least one exception (see GO:0030698).								molecular_function											owl:Class	
GO:1905056	biolink:NamedThing	P-type calcium transporter activity involved in regulation of presynaptic cytosolic calcium ion concentration	A calcium-transporting P-type ATPase activity involved in regulation of presynaptic cytosolic calcium ion concentration.	tmpzr1t_l9r_go_relaxed.owl	calcium-translocating P-type ATPase activity involved in regulation of presynaptic cytosolic calcium ion concentration|Ca(2+)-transporting ATPase activity involved in regulation of presynaptic cytosolic calcium ion concentration|calcium efflux ATPase involved in regulation of presynaptic cytosolic calcium ion concentration|calcium ABC transporter involved in regulation of presynaptic cytosolic calcium ion concentration|ATP phosphohydrolase (Ca2+-transporting) involved in regulation of presynaptic cytosolic calcium ion concentration|Ca2+-pumping ATPase activity involved in regulation of presynaptic cytosolic calcium ion concentration|plasma membrane Ca-ATPase involved in regulation of presynaptic cytosolic calcium ion concentration|calcium transporting ATPase activity involved in regulation of presynaptic cytosolic calcium ion concentration|calcium-transporting ATPase activity involved in regulation of presynaptic cytosolic calcium ion concentration|ATPase-coupled calcium ion transmembrane transporter activity involved in regulation of presynaptic cytosolic calcium levels|Ca2+-transporting ATPase activity involved in regulation of presynaptic cytosolic calcium ion concentration							dos	2016-03-17T14:35:25Z					molecular_function											owl:Class	
GO:0002696	biolink:NamedThing	positive regulation of leukocyte activation	Any process that activates or increases the frequency, rate, or extent of leukocyte activation.	tmpzr1t_l9r_go_relaxed.owl	upregulation of leukocyte activation|positive regulation of immune cell activation|positive regulation of leucocyte activation|up-regulation of leukocyte activation|up regulation of leukocyte activation|stimulation of leukocyte activation|activation of leukocyte activation													biological_process											owl:Class	
GO:0002694	biolink:NamedThing	regulation of leukocyte activation	Any process that modulates the frequency, rate, or extent of leukocyte activation.	tmpzr1t_l9r_go_relaxed.owl	regulation of leucocyte activation|regulation of immune cell activation													biological_process											owl:Class	
GO:0048925	biolink:NamedThing	lateral line system development	The process whose specific outcome is the progression of the lateral line system over time, from its formation to the mature structure. The lateral line system is a network of sensory organs (neuromasts) and lateral line nerves located superficially on the skin or just under the skin in fluid-filled canals on the head and body of all fishes and most amphibians. The lateral line system develops from cranial ectodermal placodes situated between the eye and ear.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0070555	biolink:NamedThing	response to interleukin-1	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-1 stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to IL-1													biological_process											owl:Class	
GO:0047121	biolink:NamedThing	isoquinoline 1-oxidoreductase activity	Catalysis of the reaction: A + H(2)O + isoquinoline = AH(2) + isoquinolin-1(2H)-one.	tmpzr1t_l9r_go_relaxed.owl	isoquinoline:acceptor 1-oxidoreductase (hydroxylating)				KEGG_REACTION:R05151|MetaCyc:1.3.99.16-RXN|RHEA:11588|EC:1.3.99.16									molecular_function											owl:Class	
GO:0090200	biolink:NamedThing	positive regulation of release of cytochrome c from mitochondria	Any process that increases the rate, frequency or extent of release of cytochrome c from mitochondria, the process in which cytochrome c is enabled to move from the mitochondrial intermembrane space into the cytosol, which is an early step in apoptosis and leads to caspase activation.	tmpzr1t_l9r_go_relaxed.owl						The release of cytochrome c from mitochondria is a central event in the signaling phase of the apoptotic process, and it is often used by researchers to monitor this type of cell death. Any event that induces apoptosis will at some point induce the release of cytochrome c from mitochondria. Therefore, this term should only be used to annotate gene products that directly and positively regulate this process.		tb	2009-12-18T11:35:20Z					biological_process											owl:Class	
GO:0110024	biolink:NamedThing	positive regulation of cardiac muscle myoblast proliferation	Any process that activates or increases the frequency, rate or extent of cardiac muscle myoblast proliferation.	tmpzr1t_l9r_go_relaxed.owl								kmv	2017-06-29T15:24:16Z					biological_process											owl:Class	
GO:0006181	biolink:NamedThing	dGMP biosynthetic process	The chemical reactions and pathways resulting in the formation of dGMP, deoxyguanosine monophosphate (2'-deoxyguanosine 5'-phosphate).	tmpzr1t_l9r_go_relaxed.owl	dGMP biosynthesis|dGMP anabolism|dGMP synthesis|dGMP formation													biological_process											owl:Class	
GO:0015899	biolink:NamedThing	aminotriazole transport	The directed movement of aminotriazole into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Aminotriazole is an effective weed killer that also possesses some antithyroid activity.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0051631	biolink:NamedThing	regulation of acetylcholine uptake	Any process that modulates the frequency, rate or extent of the directed movement of the neurotransmitter acetylcholine into a cell.	tmpzr1t_l9r_go_relaxed.owl	regulation of acetylcholine import													biological_process											owl:Class	
GO:0035867	biolink:NamedThing	alphav-beta3 integrin-IGF-1-IGF1R complex	A protein complex that consists of an alphav-beta3 integrin complex bound to insulin-like growth factor-1 (IGF-1) and type I insulin-like growth factor receptor (IGF1R). IGF1R is a heterotetramer that consists of two alpha-subunits and two beta-subunits.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-05-25T03:06:30Z					cellular_component											owl:Class	
GO:0009707	biolink:NamedThing	chloroplast outer membrane	The outer, i.e. cytoplasm-facing, lipid bilayer of the chloroplast envelope.	tmpzr1t_l9r_go_relaxed.owl	chloroplast outer envelope													cellular_component											owl:Class	
GO:0030881	biolink:NamedThing	beta-2-microglobulin binding	Binding to beta-2-microglobulin.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:2001073	biolink:NamedThing	cyclodextrin binding	Binding to cyclodextrin.	tmpzr1t_l9r_go_relaxed.owl								jl	2011-09-14T12:24:30Z					molecular_function											owl:Class	
GO:0097085	biolink:NamedThing	interferon regulatory factor 3-interferon regulatory factor 5 complex	An interferon regulatory factor complex that consists of a heterodimer of interferon regulatory factor 3 and interferon regulatory factor 5.	tmpzr1t_l9r_go_relaxed.owl	IRF3:IRF5 complex							pr	2011-06-21T06:30:30Z					cellular_component											owl:Class	
GO:0097071	biolink:NamedThing	interferon regulatory factor complex	A protein complex that consists of two interferon regulatory proteins (IRFs); may be homodimeric or heterodimeric. The activation of a latent closed conformation of IRF in the cytoplasm is triggered by phosphorylation of Ser/Thr residues in a C-terminal region. Phosphorylation stimulates the C-terminal autoinhibitory domain to attain a highly extended conformation triggering dimerization through extensive contacts to a second subunit.	tmpzr1t_l9r_go_relaxed.owl	IRF complex							pr	2011-06-15T04:22:30Z					cellular_component											owl:Class	
GO:0008191	biolink:NamedThing	metalloendopeptidase inhibitor activity	Binds to and stops, prevents or reduces the activity of metalloendopeptidases, enzymes that catalyze the hydrolysis of nonterminal peptide bonds in a polypeptide chain and contain a chelated metal ion at their active sites which is essential to their catalytic activity.	tmpzr1t_l9r_go_relaxed.owl	metalloproteinase inhibitor|metalloprotease inhibitor													molecular_function											owl:Class	
GO:1903053	biolink:NamedThing	regulation of extracellular matrix organization	Any process that modulates the frequency, rate or extent of extracellular matrix organization.	tmpzr1t_l9r_go_relaxed.owl	regulation of extracellular matrix organization and biogenesis|regulation of extracellular matrix organisation							rl	2014-05-23T17:15:41Z					biological_process											owl:Class	
GO:0061316	biolink:NamedThing	canonical Wnt signaling pathway involved in heart development	The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes that contributes to the progression of the heart over time. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes.	tmpzr1t_l9r_go_relaxed.owl	canonical Wnt receptor signaling pathway involved in heart development|canonical Wnt-activated signaling pathway involved in heart development|canonical Wnt receptor signalling pathway involved in heart development							dph	2010-09-24T09:25:03Z					biological_process											owl:Class	
GO:0021695	biolink:NamedThing	cerebellar cortex development	The process whose specific outcome is the progression of the cerebellar cortex over time, from its formation to the mature structure. The cerebellar cortex is a thin mantle of gray matter that covers the surface of each cerebral hemisphere. It has a characteristic morphology with convolutions (gyri) and crevices (sulci) that have specific functions. Six layers of nerve cells and the nerve pathways that connect them comprise the cerebellar cortex. Together, these regions are responsible for the processes of conscious thought, perception, emotion and memory as well as advanced motor function.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0086027	biolink:NamedThing	AV node cell to bundle of His cell signaling	Any process that mediates the transfer of information from an AV node cardiac muscle cell to a bundle of His cardiomyocyte.	tmpzr1t_l9r_go_relaxed.owl	AV node cell to bundle of His cell signalling|atrioventricular node to bundle of His cell signaling							tb	2011-11-11T02:02:14Z					biological_process											owl:Class	
GO:0031068	biolink:NamedThing	positive regulation of histone deacetylation at centromere	Any process that activates or increases the frequency, rate or extent of the removal of acetyl groups from histones in centromeric DNA.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of histone deacetylation at centromere|up regulation of histone deacetylation at centromere|upregulation of histone deacetylation at centromere|activation of histone deacetylation at centromere|stimulation of histone deacetylation at centromere													biological_process											owl:Class	
GO:0031065	biolink:NamedThing	positive regulation of histone deacetylation	Any process that activates or increases the frequency, rate or extent of the removal of acetyl groups from histones.	tmpzr1t_l9r_go_relaxed.owl	up regulation of histone deacetylation|up-regulation of histone deacetylation|upregulation of histone deacetylation|stimulation of histone deacetylation|activation of histone deacetylation													biological_process											owl:Class	
GO:0032273	biolink:NamedThing	positive regulation of protein polymerization	Any process that activates or increases the frequency, rate or extent of the process of creating protein polymers.	tmpzr1t_l9r_go_relaxed.owl	stimulation of protein polymerization|activation of protein polymerization|up-regulation of protein polymerization|upregulation of protein polymerization|up regulation of protein polymerization													biological_process											owl:Class	
GO:0010582	biolink:NamedThing	floral meristem determinacy	The process in which a floral meristem becomes determinate (i.e. ceases to produce lateral organs and may or may not terminally differentiate).	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0010022	biolink:NamedThing	meristem determinacy	The process in which a meristem becomes determinate (i.e. ceases to produce lateral organs and may or may not terminally differentiate).	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0048280	biolink:NamedThing	vesicle fusion with Golgi apparatus	The joining of the lipid bilayer membrane around a vesicle to the lipid bilayer membrane around the Golgi.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0007030	biolink:NamedThing	Golgi organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the Golgi apparatus.	tmpzr1t_l9r_go_relaxed.owl	Golgi organisation|Golgi organization and biogenesis													biological_process											owl:Class	
GO:1901480	biolink:NamedThing	oleate transmembrane transporter activity	Enables the transfer of oleate from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	oleate transporter activity				RHEA:33655			ab	2012-10-07T17:11:56Z					molecular_function											owl:Class	
GO:0015207	biolink:NamedThing	adenine transmembrane transporter activity	Enables the transfer of adenine, 6-aminopurine, from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-5672027|Reactome:R-HSA-163215|RHEA:34999									molecular_function											owl:Class	
GO:0005345	biolink:NamedThing	purine nucleobase transmembrane transporter activity	Enables the transfer of purine nucleobases, one of the two classes of nitrogen-containing ring compounds found in DNA and RNA, from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	purine transmembrane transporter activity|purine base transmembrane transporter activity													molecular_function											owl:Class	
GO:0097065	biolink:NamedThing	anterior head development	The process whose specific outcome is the progression of the anterior part of the head over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl								pr	2011-06-08T12:38:11Z					biological_process											owl:Class	
GO:0060322	biolink:NamedThing	head development	The biological process whose specific outcome is the progression of a head from an initial condition to its mature state. The head is the anterior-most division of the body.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0006109	biolink:NamedThing	regulation of carbohydrate metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving carbohydrates.	tmpzr1t_l9r_go_relaxed.owl	regulation of carbohydrate metabolism													biological_process											owl:Class	
GO:0072085	biolink:NamedThing	specification of connecting tubule identity	The process in which the connecting tubule of the kidney nephron acquires its identity.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-02-01T02:49:11Z					biological_process											owl:Class	
GO:0072081	biolink:NamedThing	specification of nephron tubule identity	The process in which the tubules arranged along the proximal/distal axis of the nephron acquire their identity.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-02-01T02:42:34Z					biological_process											owl:Class	
GO:0016768	biolink:NamedThing	spermine synthase activity	Catalysis of the reaction: S-adenosylmethioninamine + spermidine = 5'-methylthioadenosine + spermine.	tmpzr1t_l9r_go_relaxed.owl	spermine synthetase activity|spermidine aminopropyltransferase activity|S-adenosylmethioninamine:spermidine 3-aminopropyltransferase activity				Reactome:R-HSA-351210|MetaCyc:SPERMINE-SYNTHASE-RXN|RHEA:19973|EC:2.5.1.22									molecular_function											owl:Class	
GO:1900516	biolink:NamedThing	negative regulation of xylose catabolic process to ethanol	Any process that stops, prevents or reduces the frequency, rate or extent of xylose catabolic process to ethanol.	tmpzr1t_l9r_go_relaxed.owl	down regulation of xylose catabolic process to ethanol|downregulation of xylose catabolic process to ethanol|down regulation of xylose catabolism to ethanol|downregulation of xylose catabolism to ethanol|down-regulation of xylose catabolism to ethanol|inhibition of xylose catabolic process to ethanol|inhibition of xylose catabolism to ethanol|down-regulation of xylose catabolic process to ethanol|negative regulation of xylose catabolism to ethanol							tt	2012-05-02T04:09:17Z					biological_process											owl:Class	
GO:0014885	biolink:NamedThing	detection of injury involved in regulation of muscle adaptation	The series of events by which an injury stimulus is received and converted into a molecular signal. This occurs as part of the regulation of muscle adaptation.	tmpzr1t_l9r_go_relaxed.owl	detection of injury involved in regulation of muscle plasticity													biological_process											owl:Class	
GO:0014822	biolink:NamedThing	detection of wounding	The series of events by which an injury stimulus is received and converted into a molecular signal.	tmpzr1t_l9r_go_relaxed.owl	detection of injury													biological_process											owl:Class	
GO:0060115	biolink:NamedThing	vestibular receptor cell fate commitment	The process in which a cell becomes committed to become a vestibular receptor cell.	tmpzr1t_l9r_go_relaxed.owl	vestibular hair cell fate commitment													biological_process											owl:Class	
GO:1901989	biolink:NamedThing	positive regulation of cell cycle phase transition	Any process that activates or increases the frequency, rate or extent of cell cycle phase transition.	tmpzr1t_l9r_go_relaxed.owl	upregulation of cell cycle transition|activation of cell cycle phase transition|up-regulation of cell cycle transition|upregulation of cell cycle phase transition|up regulation of cell cycle phase transition|up-regulation of cell cycle phase transition|up regulation of cell cycle transition|activation of cell cycle transition|positive regulation of cell cycle transition							jl	2013-03-19T16:11:37Z					biological_process											owl:Class	
GO:1903860	biolink:NamedThing	negative regulation of dendrite extension	Any process that stops, prevents or reduces the frequency, rate or extent of dendrite extension.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of dendrite retraction|downregulation of dendrite extension|down regulation of dendrite extension|up regulation of dendrite retraction|down-regulation of dendrite extension|inhibition of dendrite extension					An example of this is Mul1 in mouse (UniProt ID Q8VCM5) in PMID:24898855 inferred from mutant phenotype.		pad	2015-02-02T15:34:00Z					biological_process											owl:Class	
GO:2001288	biolink:NamedThing	positive regulation of caveolin-mediated endocytosis	Any process that activates or increases the frequency, rate or extent of caveolin-mediated endocytosis.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of caveolae-mediated endocytosis|positive regulation of caveolin-dependent endocytosis|positive regulation of caveolae-dependent endocytosis							yaf	2011-12-15T04:13:32Z					biological_process											owl:Class	
GO:0051624	biolink:NamedThing	inhibition of norepinephrine uptake	Any process that prevents the activation of the directed movement of norepinephrine into a cell.	tmpzr1t_l9r_go_relaxed.owl	inhibition of noradrenaline uptake|inhibition of levarterenol uptake|inhibition of norepinephrine import													biological_process											owl:Class	
GO:0051622	biolink:NamedThing	negative regulation of norepinephrine uptake	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of norepinephrine into a cell.	tmpzr1t_l9r_go_relaxed.owl	downregulation of norepinephrine uptake|negative regulation of norepinephrine import|down regulation of norepinephrine uptake|down-regulation of norepinephrine uptake|negative regulation of levarterenol uptake|negative regulation of noradrenaline uptake													biological_process											owl:Class	
GO:0006606	biolink:NamedThing	protein import into nucleus	The directed movement of a protein from the cytoplasm to the nucleus.	tmpzr1t_l9r_go_relaxed.owl	establishment of protein localization to nucleus|protein import into cell nucleus|protein nucleus import|protein transport from cytoplasm to nucleus													biological_process											owl:Class	
GO:0034504	biolink:NamedThing	protein localization to nucleus	A process in which a protein transports or maintains the localization of another protein to the nucleus.	tmpzr1t_l9r_go_relaxed.owl	protein localization in cell nucleus|protein localization in nucleus|protein targeting to nucleus|protein localisation to nucleus								2012-11-07T15:45:54Z			GO:0044744		biological_process											owl:Class	
GO:1900712	biolink:NamedThing	positive regulation of tensidol B biosynthetic process	Any process that activates or increases the frequency, rate or extent of tensidol B biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of tensidol B biosynthesis|activation of tensidol B anabolism|upregulation of tensidol B biosynthesis|activation of tensidol B synthesis|upregulation of tensidol B synthesis|upregulation of tensidol B anabolism|up regulation of tensidol B biosynthetic process|positive regulation of tensidol B anabolism|activation of tensidol B biosynthesis|up regulation of tensidol B anabolism|up regulation of tensidol B biosynthesis|up-regulation of tensidol B biosynthesis|upregulation of tensidol B biosynthetic process|up-regulation of tensidol B formation|activation of tensidol B formation|up regulation of tensidol B synthesis|activation of tensidol B biosynthetic process|up regulation of tensidol B formation|up-regulation of tensidol B synthesis|positive regulation of tensidol B synthesis|up-regulation of tensidol B biosynthetic process|positive regulation of tensidol B formation|up-regulation of tensidol B anabolism|upregulation of tensidol B formation							di	2012-05-22T05:03:23Z					biological_process											owl:Class	
GO:1900710	biolink:NamedThing	regulation of tensidol B biosynthetic process	Any process that modulates the frequency, rate or extent of tensidol B biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of tensidol B synthesis|regulation of tensidol B anabolism|regulation of tensidol B biosynthesis|regulation of tensidol B formation							di	2012-05-22T05:02:55Z					biological_process											owl:Class	
GO:0010581	biolink:NamedThing	regulation of starch biosynthetic process	An process which modulate the frequency, rate or extent of starch biosynthesis, the chemical reactions and pathways resulting in the formation of starch.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0015800	biolink:NamedThing	acidic amino acid transport	The directed movement of acidic amino acids, amino acids with a pH below 7, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0071674	biolink:NamedThing	mononuclear cell migration	The movement of a mononuclear cell within or between different tissues and organs of the body.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-02-16T02:11:00Z					biological_process											owl:Class	
GO:0002048	biolink:NamedThing	pyoverdine metabolic process	The chemical reactions and pathways involving the siderochrome pyoverdine.	tmpzr1t_l9r_go_relaxed.owl	pyoverdine metabolism													biological_process											owl:Class	
GO:0033298	biolink:NamedThing	contractile vacuole organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a contractile vacuole. A specialized vacuole that fills with water from the cytoplasm and then discharges this externally by the opening of contractile vacuole pores.	tmpzr1t_l9r_go_relaxed.owl	contractile vacuole organization and biogenesis|contractile vacuole organisation													biological_process											owl:Class	
GO:0070005	biolink:NamedThing	cysteine-type aminopeptidase activity	Catalysis of the hydrolysis of a single N-terminal amino acid residue from a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/19681			EC:3.4.18.-									molecular_function											owl:Class	
GO:0070004	biolink:NamedThing	cysteine-type exopeptidase activity	Catalysis of the hydrolysis of C- or N-terminal peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0018303	biolink:NamedThing	iron incorporation into iron-sulfur cluster via tris-L-cysteinyl-L-N3'-histidino tetrairon tetrasulfide	The incorporation of iron into a 4Fe-4S iron-sulfur cluster via tris-L-cysteinyl-L-N3'-histidino tetrairon tetrasulfide.	tmpzr1t_l9r_go_relaxed.owl	iron incorporation into iron-sulphur cluster via tris-L-cysteinyl-L-N3'-histidino tetrairon tetrasulphide				RESID:AA0285									biological_process											owl:Class	
GO:1900442	biolink:NamedThing	positive regulation of filamentous growth of a population of unicellular organisms in response to neutral pH	Any process that activates or increases the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to neutral pH.	tmpzr1t_l9r_go_relaxed.owl	activation of filamentous growth of a population of unicellular organisms in response to neutral pH|up regulation of filamentous growth of a population of unicellular organisms in response to neutral pH|upregulation of filamentous growth of a population of unicellular organisms in response to neutral pH|up-regulation of filamentous growth of a population of unicellular organisms in response to neutral pH							di	2012-04-25T05:56:06Z					biological_process											owl:Class	
GO:1900945	biolink:NamedThing	negative regulation of isoprene metabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of isoprene metabolic process.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of 2-methyl-1,3-butadiene metabolism|down-regulation of isoprene metabolism|inhibition of hemiterpene metabolic process|negative regulation of isoprene metabolism|downregulation of hemiterpene metabolic process|inhibition of 2-methyl-1,3-butadiene metabolism|down-regulation of hemiterpene metabolism|down regulation of 2-methyl-1,3-butadiene metabolism|downregulation of 2-methyl-1,3-butadiene metabolism|down regulation of 2-methyl-1,3-butadiene metabolic process|down-regulation of 2-methyl-1,3-butadiene metabolic process|inhibition of 2-methyl-1,3-butadiene metabolic process|downregulation of 2-methyl-1,3-butadiene metabolic process|down regulation of isoprene metabolic process|negative regulation of 2-methyl-1,3-butadiene metabolic process|downregulation of isoprene metabolism|down-regulation of isoprene metabolic process|inhibition of isoprene metabolism|inhibition of hemiterpene metabolism|down regulation of hemiterpene metabolism|negative regulation of hemiterpene metabolism|downregulation of hemiterpene metabolism|down regulation of isoprene metabolism|inhibition of isoprene metabolic process|negative regulation of hemiterpene metabolic process|down-regulation of hemiterpene metabolic process|down-regulation of 2-methyl-1,3-butadiene metabolism|down regulation of hemiterpene metabolic process|downregulation of isoprene metabolic process							tt	2012-06-14T03:19:33Z					biological_process											owl:Class	
GO:0071981	biolink:NamedThing	exit from diapause	The dormancy process that results in exit from diapause. Diapause is a neurohormonally mediated, dynamic state of low metabolic activity. Associated characteristics of this form of dormancy include reduced morphogenesis, increased resistance to environmental extremes, and altered or reduced behavioral activity. Full expression develops in a species-specific manner, usually in response to a number of environmental stimuli that precede unfavorable conditions. Once diapause has begun, metabolic activity is suppressed even if conditions favorable for development prevail. Once initiated, only certain stimuli are capable of releasing the organism from this state, and this characteristic is essential in distinguishing diapause from hibernation.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-10-21T04:45:40Z					biological_process											owl:Class	
GO:0080059	biolink:NamedThing	flavonol 3-O-arabinosyltransferase activity	Catalysis of the reaction: UDP-arabinose + a flavonol = UDP + a flavonol 3-O-D-arabinoside.	tmpzr1t_l9r_go_relaxed.owl								dhl	2009-04-13T02:55:11Z					molecular_function											owl:Class	
GO:0052636	biolink:NamedThing	arabinosyltransferase activity	Catalysis of the transfer of an arabinosyl group from one compound (donor) to another (acceptor).	tmpzr1t_l9r_go_relaxed.owl	arabinosyl transferase activity													molecular_function											owl:Class	
GO:0072753	biolink:NamedThing	cellular response to glutathione	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glutathione stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2012-09-25T12:27:39Z					biological_process											owl:Class	
GO:1903907	biolink:NamedThing	negative regulation of plasma membrane raft polarization	Any process that stops, prevents or reduces the frequency, rate or extent of plasma membrane raft polarization.	tmpzr1t_l9r_go_relaxed.owl	down regulation of plasma membrane raft polarization|down-regulation of plasma membrane raft polarization|downregulation of plasma membrane raft polarization|inhibition of plasma membrane raft polarization							als	2015-02-09T10:54:05Z					biological_process											owl:Class	
GO:1903906	biolink:NamedThing	regulation of plasma membrane raft polarization	Any process that modulates the frequency, rate or extent of plasma membrane raft polarization.	tmpzr1t_l9r_go_relaxed.owl								als	2015-02-09T10:53:56Z					biological_process											owl:Class	
GO:0009597	biolink:NamedThing	detection of virus	The series of events in which a stimulus from a virus is received and converted into a molecular signal.	tmpzr1t_l9r_go_relaxed.owl	perception of virus					GO:0009597 is not a child term of 'detection of symbiont ; GO:0009602' to allow annotation of a virus responding to another (often competing) virus.								biological_process											owl:Class	
GO:0010650	biolink:NamedThing	positive regulation of cell communication by electrical coupling	Any process that increases the frequency, rate or extent of cell communication via electrical coupling. Cell communication via electrical coupling is the process that mediates signaling interactions between one cell and another cell by transfer of current between their adjacent cytoplasms via intercellular protein channels.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:2000468	biolink:NamedThing	regulation of peroxidase activity	Any process that modulates the frequency, rate or extent of peroxidase activity.	tmpzr1t_l9r_go_relaxed.owl	regulation of peroxidase reaction|regulation of oxyperoxidase activity|regulation of donor:hydrogen-peroxide oxidoreductase activity							bf	2011-03-08T02:18:18Z					biological_process											owl:Class	
GO:0061832	biolink:NamedThing	basal ectoplasmic specialization	Testis-specific junction between mature Sertoli cells involved in establishing the blood-testis barrier of the Sertoli cell.	tmpzr1t_l9r_go_relaxed.owl	basal ES													cellular_component											owl:Class	
GO:0102702	biolink:NamedThing	2-carene synthase activity	Catalysis of the reaction: geranyl diphosphate <=> (+)-2-carene + diphosphoric acid.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-5122									molecular_function											owl:Class	
GO:0004802	biolink:NamedThing	transketolase activity	Catalysis of the reversible transfer of a 2-carbon ketol group (CH2OH-CO-) from a ketose phosphate donor to an aldose phosphate acceptor.	tmpzr1t_l9r_go_relaxed.owl	sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glycolaldehydetransferase activity|glycoaldehyde transferase activity|fructose 6-phosphate:D-glyceraldehyde-3-phosphate glycolaldehydetransferase activity|glycolaldehydetransferase activity				MetaCyc:1TRANSKETO-RXN|EC:2.2.1.1|Reactome:R-HSA-163751|RHEA:10508|Reactome:R-HSA-163741|Reactome:R-HSA-71324|Reactome:R-HSA-71335									molecular_function											owl:Class	
GO:0016744	biolink:NamedThing	transketolase or transaldolase activity	Catalysis of the transfer of an aldehyde or ketonic group from one compound (donor) to another (acceptor).	tmpzr1t_l9r_go_relaxed.owl	transferase activity, transferring aldehyde or ketonic groups	https://github.com/geneontology/go-ontology/issues/20486			EC:2.2.1.-							GO:0016745		molecular_function											owl:Class	
GO:0002838	biolink:NamedThing	negative regulation of immune response to tumor cell	Any process that stops, prevents, or reduces the frequency, rate, or extent of an immune response to tumor cell.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of immune response to tumor cell|inhibition of immune response to tumor cell|negative regulation of immune response to tumour cell|downregulation of immune response to tumor cell|down regulation of immune response to tumor cell													biological_process											owl:Class	
GO:0050507	biolink:NamedThing	indoxyl-UDPG glucosyltransferase activity	Catalysis of the reaction: indoxyl + UDP-D-glucose = H(+) + indican + UDP.	tmpzr1t_l9r_go_relaxed.owl	UDP-glucose:indoxyl 3-O-beta-D-glucosyltransferase activity|indoxyl-UDPG-glucosyltransferase activity				RHEA:12004|EC:2.4.1.220|MetaCyc:2.4.1.220-RXN|KEGG_REACTION:R06048									molecular_function											owl:Class	
GO:0140200	biolink:NamedThing	adenylate cyclase-activating adrenergic receptor signaling pathway involved in regulation of heart rate	An adrenergic receptor signaling pathway that modulates the frequency or rate of heart contraction.	tmpzr1t_l9r_go_relaxed.owl								pg	2018-02-16T14:33:06Z					biological_process											owl:Class	
GO:0097580	biolink:NamedThing	intracellular sequestering of copper ion	The process of binding or confining copper ions in an intracellular area such that they are separated from other components of a biological system.	tmpzr1t_l9r_go_relaxed.owl	intracellular copper ion storage|intracellular copper ion sequestering|intracellular sequestration of copper ion|intracellular retention of copper ion|intracellular storage of copper ion|intracellular copper ion retention|intracellular copper ion sequestration							pr	2014-02-28T11:21:39Z					biological_process											owl:Class	
GO:0097578	biolink:NamedThing	sequestering of copper ion	The process of binding or confining copper ions such that they are separated from other components of a biological system.	tmpzr1t_l9r_go_relaxed.owl	copper ion sequestering|copper ion sequestration|copper ion retention|sequestration of copper ion|retention of copper ion|storage of copper ion|copper ion storage							pr	2014-02-28T11:15:02Z					biological_process											owl:Class	
GO:1904897	biolink:NamedThing	regulation of hepatic stellate cell proliferation	Any process that modulates the frequency, rate or extent of hepatic stellate cell proliferation.	tmpzr1t_l9r_go_relaxed.owl	regulation of hepatic perisinusoidal cell proliferation|regulation of perisinusoidal cell proliferation|regulation of Ito cell proliferation							sl	2016-01-14T15:56:59Z					biological_process											owl:Class	
GO:0048145	biolink:NamedThing	regulation of fibroblast proliferation	Any process that modulates the frequency, rate or extent of multiplication or reproduction of fibroblast cells.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0019229	biolink:NamedThing	regulation of vasoconstriction	Any process that modulates the frequency, rate or extent of reductions in the diameter of blood vessels.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0097746	biolink:NamedThing	blood vessel diameter maintenance	Any process that modulates the diameter of blood vessels.	tmpzr1t_l9r_go_relaxed.owl	regulation of vasodilatation|blood vessel diameter homeostasis|regulation of blood vessel size|regulation of blood vessel diameter|regulation of vasodilation	https://github.com/geneontology/go-ontology/issues/12253						pr	2016-11-24T15:45:05Z			GO:0042312|GO:0050880		biological_process											owl:Class	
GO:0050165	biolink:NamedThing	pantetheine kinase activity	Catalysis of the reaction: ATP + pantetheine = ADP + pantetheine 4'-phosphate.	tmpzr1t_l9r_go_relaxed.owl	ATP:pantetheine 4'-phosphotransferase activity|pantetheine kinase (phosphorylating)				EC:2.7.1.34|RHEA:22472|MetaCyc:PANTETHEINE-KINASE-RXN									molecular_function											owl:Class	
GO:0001501	biolink:NamedThing	skeletal system development	The process whose specific outcome is the progression of the skeleton over time, from its formation to the mature structure. The skeleton is the bony framework of the body in vertebrates (endoskeleton) or the hard outer envelope of insects (exoskeleton or dermoskeleton).	tmpzr1t_l9r_go_relaxed.owl	skeletal development													biological_process											owl:Class	
GO:0010250	biolink:NamedThing	S-methylmethionine biosynthetic process	The chemical reactions and pathways resulting in the formation of S-methyl-methionine (SMM) from methionine and S-adenosyl-methionine (Ado-Met), catalyzed by methionine S-methyltransferase (MMT). SMM can be reconverted to methionine by donating a methyl group to homocysteine, and concurrent operation of this reaction and that mediated by MMT sets up the SMM cycle.	tmpzr1t_l9r_go_relaxed.owl	S-methylmethionine formation|S-methylmethionine synthesis|S-methylmethionine biosynthesis|S-methylmethionine anabolism													biological_process											owl:Class	
GO:0033477	biolink:NamedThing	S-methylmethionine metabolic process	The chemical reactions and pathways involving S-methyl-methionine (SMM). SMM can be converted to methionine by donating a methyl group to homocysteine, and concurrent operation of this reaction and that mediated by MMT sets up the SMM cycle.	tmpzr1t_l9r_go_relaxed.owl	S-methylmethionine metabolism													biological_process											owl:Class	
GO:0032735	biolink:NamedThing	positive regulation of interleukin-12 production	Any process that activates or increases the frequency, rate, or extent of interleukin-12 production.	tmpzr1t_l9r_go_relaxed.owl	up regulation of interleukin-12 production|activation of interleukin-12 production|positive regulation of IL-12 production|up-regulation of interleukin-12 production|positive regulation of interleukin-12 secretion|stimulation of interleukin-12 production|positive regulation of NKSF production|positive regulation of CLMF production|positive regulation of interleukin-12 biosynthetic process|upregulation of interleukin-12 production											GO:2001184|GO:0045084		biological_process											owl:Class	
GO:0061052	biolink:NamedThing	negative regulation of cell growth involved in cardiac muscle cell development	Any process that decreases the rate, frequency, or extent of the growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-02-25T01:11:30Z					biological_process											owl:Class	
GO:0010614	biolink:NamedThing	negative regulation of cardiac muscle hypertrophy	Any process that decreases the rate, frequency or extent of the enlargement or overgrowth of all or part of the heart due to an increase in size (not length) of individual cardiac muscle fibers, without cell division.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0043008	biolink:NamedThing	ATP-dependent protein binding	Binding to a protein or protein complex using energy from ATP hydrolysis.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0071635	biolink:NamedThing	negative regulation of transforming growth factor beta production	Any process that stops, prevents, or reduces the frequency, rate, or extent of production of transforming growth factor-beta.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of transforming growth factor-beta secretion|negative regulation of TGFbeta production|negative regulation of TGF-beta production|negative regulation of TGFB production|negative regulation of TGF-B production|negative regulation of transforming growth factor-beta production							mah	2010-02-12T10:39:51Z			GO:2001202		biological_process											owl:Class	
GO:0001815	biolink:NamedThing	positive regulation of antibody-dependent cellular cytotoxicity	Any process that activates or increases the frequency, rate or extent of antibody-dependent cellular cytotoxicity.	tmpzr1t_l9r_go_relaxed.owl	activation of antibody-dependent cellular cytotoxicity|positive regulation of antibody dependent cell killing|positive regulation of antibody dependent cell death|up-regulation of antibody-dependent cellular cytotoxicity|positive regulation of antibody-dependent cell death|positive regulation of antibody-dependent cell killing|upregulation of antibody-dependent cellular cytotoxicity|up regulation of antibody-dependent cellular cytotoxicity|stimulation of antibody-dependent cellular cytotoxicity													biological_process											owl:Class	
GO:1904438	biolink:NamedThing	regulation of iron ion import across plasma membrane	Any process that modulates the frequency, rate or extent of iron ions import across plasma membrane.	tmpzr1t_l9r_go_relaxed.owl	regulation of ferrous ion import into cell|regulation of ferrous iron import into cell|regulation of ferrous iron import across plasma membrane							rl	2015-03-04T14:37:36Z			GO:1903989		biological_process											owl:Class	
GO:0034759	biolink:NamedThing	regulation of iron ion transmembrane transport	Any process that modulates the frequency, rate or extent of the directed movement of iron ions (Fe) from one side of a membrane to the other by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	regulation of iron ion membrane transport|regulation of transmembrane Fe transport|regulation of transmembrane iron transport|regulation of transmembrane iron ion transport													biological_process											owl:Class	
GO:2000108	biolink:NamedThing	positive regulation of leukocyte apoptotic process	Any process that activates or increases the frequency, rate or extent of leukocyte apoptotic process.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of leukocyte apoptosis							mah	2010-09-15T01:42:12Z					biological_process											owl:Class	
GO:0048679	biolink:NamedThing	regulation of axon regeneration	Any process that modulates the frequency, rate or extent of axon regeneration.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0004462	biolink:NamedThing	lactoylglutathione lyase activity	Catalysis of the reaction: (R)-S-lactoylglutathione = glutathione + methylglyoxal.	tmpzr1t_l9r_go_relaxed.owl	(R)-S-lactoylglutathione methylglyoxal-lyase (isomerizing; glutathione-forming)|(R)-S-lactoylglutathione methylglyoxal-lyase (isomerizing) activity|methylglyoxalase activity|glyoxalase I activity|aldoketomutase activity|glyoxylase I|ketone-aldehyde mutase activity				RHEA:19069|Reactome:R-HSA-5694071|MetaCyc:GLYOXI-RXN|EC:4.4.1.5|KEGG_REACTION:R02530									molecular_function											owl:Class	
GO:0000274	biolink:NamedThing	mitochondrial proton-transporting ATP synthase, stator stalk	One of two stalks that connect the catalytic core of the hydrogen-transporting ATP synthase to the mitochondrial membrane-associated F0 proteins; is thought to prevent futile rotation of the catalytic core.	tmpzr1t_l9r_go_relaxed.owl	mitochondrial proton-transporting ATP synthase, peripheral stalk													cellular_component											owl:Class	
GO:0045230	biolink:NamedThing	capsule organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the capsule, a protective structure surrounding some species of bacteria and fungi.	tmpzr1t_l9r_go_relaxed.owl	capsule organization and biogenesis|capsule organisation													biological_process											owl:Class	
GO:0045229	biolink:NamedThing	external encapsulating structure organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of external structures that lie outside the plasma membrane and surround the entire cell.	tmpzr1t_l9r_go_relaxed.owl	external encapsulating structure organization and biogenesis|external encapsulating structure organisation													biological_process											owl:Class	
GO:0071347	biolink:NamedThing	cellular response to interleukin-1	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-1 stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to IL-1							mah	2009-12-11T02:49:17Z					biological_process											owl:Class	
GO:0051395	biolink:NamedThing	negative regulation of nerve growth factor receptor activity	Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of the nerve growth factor (NGF) receptor.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of nerve growth factor receptor activity|downregulation of nerve growth factor receptor activity|down regulation of nerve growth factor receptor activity|negative regulation of NGF receptor activity|inhibition of nerve growth factor receptor activity													biological_process											owl:Class	
GO:0051394	biolink:NamedThing	regulation of nerve growth factor receptor activity	Any process that modulates the frequency, rate or extent of the activity of the nerve growth factor (NGF) receptor.	tmpzr1t_l9r_go_relaxed.owl	regulation of NGF receptor activity													biological_process											owl:Class	
GO:0002884	biolink:NamedThing	negative regulation of hypersensitivity	Any process that stops, prevents, or reduces the frequency, rate, or extent of hypersensitivity.	tmpzr1t_l9r_go_relaxed.owl	inhibition of hypersensitivity|down regulation of hypersensitivity|downregulation of hypersensitivity|down-regulation of hypersensitivity													biological_process											owl:Class	
GO:1905537	biolink:NamedThing	positive regulation of eukaryotic translation initiation factor 4F complex assembly	Any process that activates or increases the frequency, rate or extent of eukaryotic translation initiation factor 4F complex assembly.	tmpzr1t_l9r_go_relaxed.owl	up regulation of eIF-4F assembly|positive regulation of eIF-4F assembly|upregulation of eIF-4F assembly|up-regulation of eukaryotic translation initiation factor 4F complex assembly|up-regulation of eIF-4F assembly|up-regulation of eIF4F assembly|upregulation of eukaryotic translation initiation factor 4F complex assembly|up regulation of eukaryotic translation initiation factor 4F complex assembly|activation of eIF4F assembly|activation of eIF-4F assembly|activation of eukaryotic translation initiation factor 4F complex assembly|positive regulation of eIF4F assembly|upregulation of eIF4F assembly|up regulation of eIF4F assembly							bc	2016-10-06T14:05:13Z					biological_process											owl:Class	
GO:0001982	biolink:NamedThing	baroreceptor response to decreased systemic arterial blood pressure	The lowering of the number of nerve impulses from baroreceptors as a result of decreased stretch of an artery that results in an increased in sympathetic nerve impulses to peripheral blood vessels.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0003084	biolink:NamedThing	positive regulation of systemic arterial blood pressure	The process that increases the force with which blood travels through the systemic arterial circulatory system.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0002122	biolink:NamedThing	fear-induced aggressive behavior	Aggressive behavior associated with attempts to flee from a threat.	tmpzr1t_l9r_go_relaxed.owl	fear-induced aggression													biological_process											owl:Class	
GO:2000260	biolink:NamedThing	regulation of blood coagulation, common pathway	Any process that modulates the frequency, rate or extent of blood coagulation, common pathway.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-11-23T11:42:40Z					biological_process											owl:Class	
GO:0015496	biolink:NamedThing	putrescine:ornithine antiporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: putrescine(out) + ornithine(in) = putrescine(in) + ornithine(out).	tmpzr1t_l9r_go_relaxed.owl	putrescine/ornithine antiporter activity|putrescine-ornithine antiporter activity|putrescine:hydrogen symporter activity													molecular_function											owl:Class	
GO:0140323	biolink:NamedThing	solute:anion antiporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: anion(in) + solute(out) = anion(out) + solute(in).	tmpzr1t_l9r_go_relaxed.owl								pg	2019-04-03T16:23:14Z					molecular_function											owl:Class	
GO:0120007	biolink:NamedThing	negative regulation of glutamatergic neuron differentiation	Any process that stops, prevents or reduces the frequency, rate or extent of glutamatergic neuron differentiation.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/13107						krc	2017-03-01T16:25:50Z					biological_process											owl:Class	
GO:0042556	biolink:NamedThing	eukaryotic elongation factor-2 kinase regulator activity	Modulates the activity of the enzyme eukaryotic elongation factor-2 kinase.	tmpzr1t_l9r_go_relaxed.owl	eEF-2 kinase regulator													molecular_function											owl:Class	
GO:0019887	biolink:NamedThing	protein kinase regulator activity	Modulates the activity of a protein kinase, an enzyme which phosphorylates a protein.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:2000490	biolink:NamedThing	negative regulation of hepatic stellate cell activation	Any process that stops, prevents or reduces the frequency, rate or extent of hepatic stellate cell activation.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-03-14T03:49:18Z					biological_process											owl:Class	
GO:2000489	biolink:NamedThing	regulation of hepatic stellate cell activation	Any process that modulates the frequency, rate or extent of hepatic stellate cell activation.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-03-14T03:48:32Z					biological_process											owl:Class	
GO:0000502	biolink:NamedThing	proteasome complex	A large multisubunit complex which catalyzes protein degradation, found in eukaryotes, archaea and some bacteria. In eukaryotes, this complex consists of the barrel shaped proteasome core complex and one or two associated proteins or complexes that act in regulating entry into or exit from the core.	tmpzr1t_l9r_go_relaxed.owl	26S proteasome|proteasome													cellular_component											owl:Class	
GO:0070242	biolink:NamedThing	thymocyte apoptotic process	Any apoptotic process in a thymocyte, an immature T cell located in the thymus.	tmpzr1t_l9r_go_relaxed.owl	thymocyte apoptosis|immature T cell apoptosis					Note that a thymocyte is an immature T cell located in the thymus (CL:0000893).								biological_process											owl:Class	
GO:0070231	biolink:NamedThing	T cell apoptotic process	Any apoptotic process in a T cell, a type of lymphocyte whose defining characteristic is the expression of a T cell receptor complex.	tmpzr1t_l9r_go_relaxed.owl	T cell apoptosis|T lymphocyte apoptosis|T-lymphocyte apoptosis|T-cell apoptosis|programmed cell death of T cells by apoptosis													biological_process											owl:Class	
GO:0015422	biolink:NamedThing	ABC-type oligosaccharide transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + oligosaccharide(out) = ADP + phosphate + oligosaccharide(in).	tmpzr1t_l9r_go_relaxed.owl	ATP-dependent oligosaccharide transmembrane transporter activity|oligosaccharide-transporting ATPase activity|oligosaccharide ABC transporter|ATPase-coupled oligosaccharide transmembrane transporter activity|ABC-type oligosaccharide transporter				EC:7.5.2.2|MetaCyc:3.6.3.18-RXN							GO:0015609		molecular_function											owl:Class	
GO:0031786	biolink:NamedThing	type 1B melatonin receptor binding	Binding to a type 1B melatonin receptor.	tmpzr1t_l9r_go_relaxed.owl	type 1B melatonin receptor ligand													molecular_function											owl:Class	
GO:0031784	biolink:NamedThing	melatonin receptor binding	Binding to a melatonin receptor.	tmpzr1t_l9r_go_relaxed.owl	melatonin receptor ligand													molecular_function											owl:Class	
GO:1905377	biolink:NamedThing	response to D-galactose	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a D-galactose stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to D-galacto-hexose|response to D-Gal							sl	2016-08-17T22:17:25Z					biological_process											owl:Class	
GO:0047678	biolink:NamedThing	arginine 2-monooxygenase activity	Catalysis of the reaction: L-arginine + O(2) = 4-guanidinobutanamide + CO(2) + H(2)O.	tmpzr1t_l9r_go_relaxed.owl	L-arginine:oxygen 2-oxidoreductase (decarboxylating)|arginine decarboxy-oxidase activity|arginine monooxygenase activity|arginine oxygenase (decarboxylating) activity				MetaCyc:ARGININE-2-MONOOXYGENASE-RXN|KEGG_REACTION:R00559|EC:1.13.12.1|RHEA:10548									molecular_function											owl:Class	
GO:0002919	biolink:NamedThing	positive regulation of peripheral B cell anergy	Any process that activates or increases the frequency, rate, or extent of peripheral B cell anergy.	tmpzr1t_l9r_go_relaxed.owl	activation of peripheral B cell anergy|up regulation of peripheral B cell anergy|up-regulation of peripheral B cell anergy|upregulation of peripheral B cell anergy|stimulation of peripheral B cell anergy													biological_process											owl:Class	
GO:2000542	biolink:NamedThing	negative regulation of gastrulation	Any process that stops, prevents or reduces the frequency, rate or extent of gastrulation.	tmpzr1t_l9r_go_relaxed.owl								yaf	2011-04-01T04:10:08Z					biological_process											owl:Class	
GO:0002104	biolink:NamedThing	endonucleolytic cleaveage between 4.5S rRNA and 5S rRNA of tetracistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 4.5S-rRNA, 5S-rRNA)	Endonucleolytic cleavage between the 5S rRNA and the 4.5S rRNA of an rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, Large Subunit (LSU) the 4.5S rRNA, and the 5S rRNA in that order from 5' to 3' along the primary transcript. Note that the use of the word tetracistronic refers only to the number of mature rRNA molecules which will be produced from the primary transcript and ignores tRNAs that may also be present within the primary transcript.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0002103	biolink:NamedThing	endonucleolytic cleavage of tetracistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 4.5S-rRNA, 5S-rRNA)	Endonucleolytic cleavage of a pre-rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, Large Subunit (LSU) the 4.5S rRNA, and the 5S rRNA in that order from 5' to 3' along the primary transcript. Primary ribosomal RNA transcripts with four genes, in this order, are produced in the chloroplasts of vascular plants. Note that the use of the word tetracistronic refers only to the number of mature rRNA molecules which will be produced from the primary transcript and ignores tRNAs that may also be present within the primary transcript.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0006399	biolink:NamedThing	tRNA metabolic process	The chemical reactions and pathways involving tRNA, transfer RNA, a class of relatively small RNA molecules responsible for mediating the insertion of amino acids into the sequence of nascent polypeptide chains during protein synthesis. Transfer RNA is characterized by the presence of many unusual minor bases, the function of which has not been completely established.	tmpzr1t_l9r_go_relaxed.owl	tRNA metabolism													biological_process											owl:Class	
GO:0034660	biolink:NamedThing	ncRNA metabolic process	The chemical reactions and pathways involving non-coding RNA transcripts (ncRNAs).	tmpzr1t_l9r_go_relaxed.owl	ncRNA metabolism													biological_process											owl:Class	
GO:0046260	biolink:NamedThing	trinitrotoluene catabolic process	The chemical reactions and pathways resulting in the breakdown of trinitrotoluene, a methylated benzene entity with three NO2 groups attached to it. This includes the explosive TNT, 1-methyl-2,4,6-trinitrobenzene.	tmpzr1t_l9r_go_relaxed.owl	trinitrotoluene catabolism|trinitrotoluene degradation|trinitrotoluene breakdown													biological_process											owl:Class	
GO:0046263	biolink:NamedThing	nitrotoluene catabolic process	The chemical reactions and pathways resulting in the breakdown of nitrotoluene, any methylbenzene molecule with NO2 group(s) attached.	tmpzr1t_l9r_go_relaxed.owl	nitrotoluene degradation|nitrotoluene breakdown|nitrotoluene catabolism													biological_process											owl:Class	
GO:0110137	biolink:NamedThing	regulation of imaginal disc-derived leg joint morphogenesis	Any process that modulates the frequency, rate or extent of imaginal disc-derived leg joint morphogenesis, the process in which the anatomical structure of the imaginal disc-derived leg joint is generated and organized.	tmpzr1t_l9r_go_relaxed.owl								kmv	2019-02-12T15:31:25Z					biological_process											owl:Class	
GO:1905794	biolink:NamedThing	response to puromycin	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a puromycin stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to 3'-deoxy-N,N-dimethyl-3'-(O-methyl-L-tyrosinamido)adenosine							sl	2017-01-10T21:13:18Z					biological_process											owl:Class	
GO:0014074	biolink:NamedThing	response to purine-containing compound	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a purine-containing compound stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to purine													biological_process											owl:Class	
GO:0033668	biolink:NamedThing	negative regulation by symbiont of host apoptotic process	Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of programmed cell death in the host, where programmed cell death proceeds by apoptosis. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	downregulation by organism of host apoptotic programmed cell death|negative regulation by symbiont of host apoptosis|inhibition by organism of host apoptotic programmed cell death|down regulation by organism of host apoptotic programmed cell death|down-regulation by organism of host apoptotic programmed cell death					Note that term is to be used to annotate gene products in the symbiont. To annotate host gene products, consider the biological process term 'negative regulation of apoptosis ; GO:0043066'.								biological_process											owl:Class	
GO:0090524	biolink:NamedThing	cytochrome-b5 reductase activity, acting on NADH	Catalysis of the reaction: NADH + H+ + 2 ferricytochrome b(5) = NAD+ + 2 ferrocytochrome b(5).	tmpzr1t_l9r_go_relaxed.owl	cytochrome b5 reductase activity							tb	2013-01-11T12:21:50Z					molecular_function											owl:Class	
GO:0004128	biolink:NamedThing	cytochrome-b5 reductase activity, acting on NAD(P)H	Catalysis of the reaction: NAD(P)H + H+ + 2 ferricytochrome b(5) = NAD(P)+ + 2 ferrocytochrome b(5).	tmpzr1t_l9r_go_relaxed.owl	NADH-cytochrome-b5 reductase activity|NADH-ferricytochrome b5 oxidoreductase activity|NADH-cytochrome b5 reductase activity|reduced nicotinamide adeninedinucleotide-cytochrome b5 reductase activity|NADH 5alpha-reductase activity|cytochrome b5 reductase activity|NADH:ferricytochrome-b5 oxidoreductase activity|dihydronicotinamide adenine dinucleotide-cytochrome b5 reductase activity				Reactome:R-HSA-198824|MetaCyc:CYTOCHROME-B5-REDUCTASE-RXN|EC:1.6.2.2|RHEA:46680|Reactome:R-HSA-6806831									molecular_function											owl:Class	
GO:0002889	biolink:NamedThing	regulation of immunoglobulin mediated immune response	Any process that modulates the frequency, rate, or extent of an immunoglobulin mediated immune response.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1900341	biolink:NamedThing	positive regulation of methane biosynthetic process from formic acid	Any process that activates or increases the frequency, rate or extent of methane biosynthetic process from formic acid.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of methane biosynthetic process from formic acid|upregulation of methane biosynthetic process from formic acid|activation of methane biosynthetic process from formic acid|up regulation of methane biosynthetic process from formic acid							tt	2012-04-06T02:05:11Z					biological_process											owl:Class	
GO:0000416	biolink:NamedThing	positive regulation of histone H3-K36 methylation	Any process that activates or increases the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 36 of histone H3.	tmpzr1t_l9r_go_relaxed.owl	upregulation of histone H3-K36 methylation|activation of histone H3-K36 methylation|stimulation of histone H3-K36 methylation|up regulation of histone H3-K36 methylation|up-regulation of histone H3-K36 methylation													biological_process											owl:Class	
GO:0061986	biolink:NamedThing	negative regulation of transcription by glucose	Any process involving glucose that decreases the frequency, rate or extent or transcription.	tmpzr1t_l9r_go_relaxed.owl								dph	2018-02-15T17:39:14Z					biological_process											owl:Class	
GO:0046015	biolink:NamedThing	regulation of transcription by glucose	Any process involving glucose that modulates the frequency, rate or extent or transcription.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0033510	biolink:NamedThing	luteolin metabolic process	The chemical reactions and pathways involving luteolin, 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4-one.	tmpzr1t_l9r_go_relaxed.owl	luteolin metabolism													biological_process											owl:Class	
GO:0043185	biolink:NamedThing	vascular endothelial growth factor receptor 3 binding	Binding to a vascular endothelial growth factor receptor 3.	tmpzr1t_l9r_go_relaxed.owl	VEGF receptor 3 binding|fms-like-tyrosine kinase (Flt)-4 binding|VEGFR 3 binding													molecular_function											owl:Class	
GO:0005172	biolink:NamedThing	vascular endothelial growth factor receptor binding	Binding to a vascular endothelial growth factor receptor.	tmpzr1t_l9r_go_relaxed.owl	VEGFR binding|vascular endothelial growth factor|VEGF receptor binding|vascular endothelial growth factor receptor ligand													molecular_function											owl:Class	
GO:0102456	biolink:NamedThing	cyanidin 3-O-glucoside 5-O-glucosyltransferase (sinapoyl-glucose dependent) activity	Catalysis of the reaction: cyanidin 3-O-beta-D-glucoside betaine + 1-O-sinapoyl-beta-D-glucose <=> cyanin betaine + trans-sinapate + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-13967									molecular_function											owl:Class	
GO:1904297	biolink:NamedThing	positive regulation of osmolarity-sensing cation channel activity	Any process that activates or increases the frequency, rate or extent of osmolarity-sensing cation channel activity.	tmpzr1t_l9r_go_relaxed.owl	activation of osmolarity-sensing cation channel activity|up regulation of osmolarity-sensing cation channel activity|upregulation of osmolarity-sensing cation channel activity|up-regulation of osmolarity-sensing cation channel activity							sl	2015-06-09T17:35:52Z					biological_process											owl:Class	
GO:0102506	biolink:NamedThing	cyanidin 3-O-glucoside 5-O-glucosyltransferase (acyl-glucose dependent) activity	Catalysis of the reaction: cyanidin 3-O-beta-D-glucoside betaine + 1-O-feruloyl-beta-D-glucose = cyanin betaine + ferulate + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-14432|EC:2.4.1.299									molecular_function											owl:Class	
GO:0005471	biolink:NamedThing	ATP:ADP antiporter activity	Catalysis of the reaction: ATP(out) + ADP(in) = ATP(in) + ADP(out).	tmpzr1t_l9r_go_relaxed.owl	ATP/ADP exchange|ADP/ATP carrier protein|adenine nucleotide translocase|ADP/ATP translocase|ATP/ADP exchanger											GO:0005349		molecular_function											owl:Class	
GO:1902213	biolink:NamedThing	positive regulation of prolactin signaling pathway	Any process that activates or increases the frequency, rate or extent of prolactin signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of prolactin-mediated signaling pathway|upregulation of PRL signaling pathway|activation of prolactin-mediated signaling pathway|up regulation of PRL signaling pathway|up regulation of prolactin signaling pathway|upregulation of prolactin signaling pathway|positive regulation of PRL signaling pathway|up regulation of prolactin-mediated signaling pathway|up-regulation of PRL signaling pathway|upregulation of prolactin-mediated signaling pathway|positive regulation of prolactin-mediated signaling pathway|activation of prolactin signaling pathway|activation of PRL signaling pathway|up-regulation of prolactin signaling pathway							lb	2013-06-12T10:10:18Z					biological_process											owl:Class	
GO:1902211	biolink:NamedThing	regulation of prolactin signaling pathway	Any process that modulates the frequency, rate or extent of prolactin signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	regulation of prolactin-mediated signaling pathway|regulation of PRL signaling pathway							lb	2013-06-12T10:10:07Z					biological_process											owl:Class	
GO:0035349	biolink:NamedThing	coenzyme A transmembrane transport	The process in which coenzyme A is transported across a membrane. Coenzyme A, 3'-phosphoadenosine-(5')diphospho(4')pantatheine, is an acyl carrier in many acylation and acyl-transfer reactions in which the intermediate is a thiol ester.	tmpzr1t_l9r_go_relaxed.owl	coenzyme A membrane transport					Note that this term is not intended for use in annotating lateral movement within membranes.		bf	2010-03-04T03:44:33Z					biological_process											owl:Class	
GO:0015880	biolink:NamedThing	coenzyme A transport	The directed movement of coenzyme A into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Coenzyme A, 3'-phosphoadenosine-(5')diphospho(4')pantatheine, is an acyl carrier in many acylation and acyl-transfer reactions in which the intermediate is a thiol ester.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0045919	biolink:NamedThing	positive regulation of cytolysis	Any process that activates or increases the frequency, rate or extent of cytolysis.	tmpzr1t_l9r_go_relaxed.owl	stimulation of cytolysis|up regulation of cytolysis|upregulation of cytolysis|up-regulation of cytolysis|activation of cytolysis													biological_process											owl:Class	
GO:0071827	biolink:NamedThing	plasma lipoprotein particle organization	A protein-lipid complex subunit organization process that results in the formation, disassembly, or alteration of a plasma lipoprotein particle. A plasma lipoprotein particle is a spherical particle with a hydrophobic core of triglycerides and/or cholesterol esters, surrounded by an amphipathic monolayer of phospholipids, cholesterol and apolipoproteins.	tmpzr1t_l9r_go_relaxed.owl	plasma lipoprotein particle organisation							mah	2010-09-08T10:32:26Z					biological_process											owl:Class	
GO:1900684	biolink:NamedThing	negative regulation of fumonisin biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of fumonisin biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of fumonisin biosynthesis|downregulation of fumonisin biosynthetic process|inhibition of fumonisin synthesis|down regulation of fumonisin synthesis|downregulation of fumonisin biosynthesis|down-regulation of fumonisin synthesis|down-regulation of fumonisin biosynthesis|negative regulation of fumonisin formation|inhibition of fumonisin formation|negative regulation of fumonisin anabolism|inhibition of fumonisin anabolism|down regulation of fumonisin biosynthesis|downregulation of fumonisin synthesis|inhibition of fumonisin biosynthetic process|down-regulation of fumonisin formation|downregulation of fumonisin anabolism|down regulation of fumonisin formation|down-regulation of fumonisin biosynthetic process|down regulation of fumonisin anabolism|downregulation of fumonisin formation|inhibition of fumonisin biosynthesis|down-regulation of fumonisin anabolism|down regulation of fumonisin biosynthetic process|negative regulation of fumonisin synthesis							di	2012-05-22T04:29:59Z					biological_process											owl:Class	
GO:1990330	biolink:NamedThing	IscS-IscU complex	A heterotetrameric protein complex involved in the sulfur transfer during iron-sulfur cluster assembly and in the modification of tRNA wobble positions. In E. coli it consisting of a central IscS dimer with the IscU protomers attached to one of the IscS units each via a disulfide (-SSH) group.	tmpzr1t_l9r_go_relaxed.owl								bhm	2014-03-17T10:08:19Z					cellular_component											owl:Class	
GO:0019810	biolink:NamedThing	putrescine binding	Binding to putrescine, 1,4-diaminobutane, the polyamine formed by decarboxylation of ornithine and the metabolic precursor of spermidine and spermine.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0019808	biolink:NamedThing	polyamine binding	Binding to a polyamine, an organic compound containing two or more amino groups.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0015731	biolink:NamedThing	3-hydroxyphenyl propanoate transport	The directed movement of 3-hydroxyphenyl propanoate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	3-hydroxyphenyl propionate transport													biological_process											owl:Class	
GO:0098997	biolink:NamedThing	fusion of virus membrane with host outer membrane	Fusion of a viral membrane with the host cell outer membrane during viral entry.	tmpzr1t_l9r_go_relaxed.owl	fusion of viral membrane with host outer membrane|viral envelope fusion with host outer membrane|viral penetration via membrane fusion|viral envelope fusion|viral-cell fusion molecule activity				VZ:3941									biological_process											owl:Class	
GO:0019064	biolink:NamedThing	fusion of virus membrane with host plasma membrane	Fusion of a viral membrane with the host cell membrane during viral entry. Results in release of the virion contents into the cytoplasm.	tmpzr1t_l9r_go_relaxed.owl	viral envelope fusion|viral-cell fusion molecule activity|viral envelope fusion with host membrane|viral envelope fusion with host cell membrane|viral entry into host cell via membrane fusion with the plasma membrane|viral penetration via membrane fusion|viral envelope fusion with host plasma membrane				VZ:987							GO:0075706		biological_process											owl:Class	
GO:0061787	biolink:NamedThing	peptidoglycan cross-bridge peptide endopeptidase activity	A peptidoglycan endopeptidase activity that acts on a peptidoglycan cross-bridge.	tmpzr1t_l9r_go_relaxed.owl	lysostaphin activity							dph	2016-09-07T16:54:02Z					molecular_function											owl:Class	
GO:0061785	biolink:NamedThing	peptidoglycan endopeptidase activity	An endopeptidase activity that uses peptidoglycan as a substrate.	tmpzr1t_l9r_go_relaxed.owl								dph	2016-09-07T16:30:48Z					molecular_function											owl:Class	
GO:1904513	biolink:NamedThing	negative regulation of initiation of premeiotic DNA replication	Any process that stops, prevents or reduces the frequency, rate or extent of initiation of premeiotic DNA replication.	tmpzr1t_l9r_go_relaxed.owl	inhibition of initiation of premeiotic DNA synthesis|negative regulation of initiation of meiotic DNA synthesis|negative regulation of meiotic DNA replication initiation|down regulation of meiotic DNA replication initiation|down-regulation of meiotic DNA replication initiation|downregulation of meiotic DNA replication initiation|down-regulation of initiation of premeiotic DNA replication|down regulation of premeiotic DNA replication initiation|down regulation of initiation of premeiotic DNA synthesis|downregulation of initiation of premeiotic DNA synthesis|inhibition of initiation of premeiotic DNA replication|inhibition of initiation of meiotic DNA synthesis|downregulation of initiation of meiotic DNA synthesis|down-regulation of premeiotic DNA replication initiation|down-regulation of initiation of meiotic DNA synthesis|down regulation of initiation of meiotic DNA synthesis|inhibition of meiotic DNA replication initiation|inhibition of premeiotic DNA replication initiation|negative regulation of initiation of premeiotic DNA synthesis|negative regulation of premeiotic DNA replication initiation|down-regulation of initiation of premeiotic DNA synthesis|downregulation of initiation of premeiotic DNA replication|downregulation of premeiotic DNA replication initiation|down regulation of initiation of premeiotic DNA replication							mah	2015-07-28T12:59:23Z					biological_process											owl:Class	
GO:0051770	biolink:NamedThing	positive regulation of nitric-oxide synthase biosynthetic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of a nitric oxide synthase enzyme.	tmpzr1t_l9r_go_relaxed.owl	up regulation of nitric-oxide synthase biosynthetic process|up-regulation of nitric-oxide synthase 2 biosynthetic process|upregulation of nitric-oxide synthase biosynthetic process|up regulation of nitric-oxide synthase 2 biosynthetic process|stimulation of nitric-oxide synthase 2 biosynthetic process|upregulation of nitric-oxide synthase 2 biosynthetic process|positive regulation of NOS2 synthase biosynthesis|positive regulation of NOS biosynthesis|positive regulation of NOS2 synthase biosynthetic process|positive regulation of NOS biosynthetic process|positive regulation of nitric-oxide synthase (type 2) biosynthetic process|activation of nitric-oxide synthase biosynthetic process|stimulation of nitric-oxide synthase biosynthetic process|positive regulation of nitric-oxide synthase 2 biosynthetic process|up-regulation of nitric-oxide synthase biosynthetic process|positive regulation of nitric-oxide synthase (type 2) biosynthesis|activation of nitric-oxide synthase 2 biosynthetic process|positive regulation of nitric-oxide synthase (type II) biosynthetic process|positive regulation of NO synthase biosynthetic process|positive regulation of nitric-oxide synthase (type II) biosynthesis|positive regulation of NO synthase biosynthesis											GO:0051773		biological_process											owl:Class	
GO:0106166	biolink:NamedThing	spindle pole body-nuclear membrane anchor activity	The binding activity of a molecule that brings together a mitotic spindle pole body and the nuclear membrane, in order to maintain specific membrane location of the spindle pole body.	tmpzr1t_l9r_go_relaxed.owl	nuclear membrane-spindle pole body anchor activity|spindle pole body nuclear membrane anchor activity	https://github.com/geneontology/go-ontology/issues/19119|https://github.com/geneontology/go-ontology/issues/20606						hjd	2019-01-18T15:57:42Z					molecular_function											owl:Class	
GO:0140475	biolink:NamedThing	spindle pole body anchor activity	The binding activity of a protein that brings together the spindle pole body and one or more other molecules, permitting them to function in a coordinated way.	tmpzr1t_l9r_go_relaxed.owl								pg	2020-06-23T15:54:56Z					molecular_function											owl:Class	
GO:1905955	biolink:NamedThing	negative regulation of endothelial tube morphogenesis	Any process that stops, prevents or reduces the frequency, rate or extent of endothelial tube morphogenesis.	tmpzr1t_l9r_go_relaxed.owl	down regulation of endothelial tube morphogenesis|inhibition of endothelial tube morphogenesis|downregulation of endothelial tube morphogenesis|down-regulation of endothelial tube morphogenesis							rph	2017-02-21T15:17:31Z					biological_process											owl:Class	
GO:1905331	biolink:NamedThing	negative regulation of morphogenesis of an epithelium	Any process that stops, prevents or reduces the frequency, rate or extent of morphogenesis of an epithelium.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of epithelium morphogenesis|inhibition of morphogenesis of an epithelium|down-regulation of epithelium morphogenesis|down regulation of morphogenesis of an epithelium|inhibition of epithelium morphogenesis|down regulation of epithelium morphogenesis|downregulation of morphogenesis of an epithelium|down-regulation of morphogenesis of an epithelium|downregulation of epithelium morphogenesis					An example of this is MMRN2 in human (Q9H8L6) in PMID:25745997 (inferred from direct assay).		bhm	2016-07-22T07:13:57Z					biological_process											owl:Class	
GO:0050881	biolink:NamedThing	musculoskeletal movement	The movement of an organism or part of an organism using mechanoreceptors, the nervous system, striated muscle and/or the skeletal system.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0050905	biolink:NamedThing	neuromuscular process	Any process pertaining to the functions of the nervous and muscular systems of an organism.	tmpzr1t_l9r_go_relaxed.owl	neuromuscular physiological process|neuromotor process													biological_process											owl:Class	
GO:0047211	biolink:NamedThing	alpha-1,4-glucan-protein synthase (ADP-forming) activity	Catalysis of the reaction: ADP-D-glucose + protein = alpha-D-glucosyl-protein + ADP.	tmpzr1t_l9r_go_relaxed.owl	1,4alpha-glucan-protein synthase (ADP-forming) activity|ADP-glucose:protein 4-alpha-D-glucosyltransferase activity|ADPglucose:protein glucosyltransferase activity|ADPglucose:protein 4-alpha-D-glucosyltransferase activity|adenosine diphosphoglucose-protein glucosyltransferase activity				EC:2.4.1.113|MetaCyc:2.4.1.113-RXN									molecular_function											owl:Class	
GO:0098627	biolink:NamedThing	protein arginine phosphatase activity	Catalysis of the reaction: protein arginine phosphate + H2O = protein arginine + phosphate.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/21517			RHEA:43380|EC:3.9.1.2	Made part of peptidyl-N-phospho-arginine phosphatase activity on the assumption that arginine phosphorylation in proteins occurs via an N link.		dos	2014-04-17T17:57:39Z					molecular_function											owl:Class	
GO:0004721	biolink:NamedThing	phosphoprotein phosphatase activity	Catalysis of the reaction: a phosphoprotein + H2O = a protein + phosphate. Together with protein kinases, these enzymes control the state of phosphorylation of cell proteins and thereby provide an important mechanism for regulating cellular activity.	tmpzr1t_l9r_go_relaxed.owl	protein phosphatase-1 activity|phosphoprotein phosphohydrolase activity|protein phosphatase-2C activity|protein phosphatase-2B activity|protein phosphatase-2A activity|protein phosphatase activity				Reactome:R-HSA-174110|Reactome:R-HSA-170153|MetaCyc:3.1.3.16-RXN|Reactome:R-HSA-2529015|Reactome:R-HSA-170161|Reactome:R-HSA-174124|Reactome:R-HSA-112383|Reactome:R-HSA-170158|Reactome:R-HSA-1363276|Reactome:R-HSA-69199|Reactome:R-HSA-167072|Reactome:R-HSA-9636684|Reactome:R-HSA-178178|Reactome:R-HSA-1363274|Reactome:R-HSA-113503									molecular_function											owl:Class	
GO:0050067	biolink:NamedThing	lysine 2-monooxygenase activity	Catalysis of the reaction: L-lysine + O(2) = 5-aminopentanamide + CO(2) + H(2)O.	tmpzr1t_l9r_go_relaxed.owl	lysine monooxygenase activity|L-lysine:oxygen 2-oxidoreductase (decarboxylating)|L-lysine-2-monooxygenase activity|lysine oxygenase activity				EC:1.13.12.2|MetaCyc:LYSINE-2-MONOOXYGENASE-RXN|RHEA:14601|KEGG_REACTION:R00449									molecular_function											owl:Class	
GO:0010897	biolink:NamedThing	negative regulation of triglyceride catabolic process	Any process that decreases the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of triglyceride.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of triacylglycerol catabolic process													biological_process											owl:Class	
GO:0050995	biolink:NamedThing	negative regulation of lipid catabolic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of lipids.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of lipid catabolic process|downregulation of lipid catabolic process|negative regulation of lipid degradation|negative regulation of lipid catabolism|negative regulation of lipid breakdown|inhibition of lipid catabolic process|down regulation of lipid catabolic process													biological_process											owl:Class	
GO:0090079	biolink:NamedThing	translation regulator activity, nucleic acid binding	Any selective and non-covalent interaction with a nucleic acid involved in the initiation, activation, perpetuation, repression or termination of polypeptide synthesis at the ribosome.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-10-19T10:19:05Z					molecular_function											owl:Class	
GO:1900628	biolink:NamedThing	positive regulation of arugosin biosynthetic process	Any process that activates or increases the frequency, rate or extent of arugosin biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	up regulation of arugosin biosynthesis|up-regulation of arugosin formation|positive regulation of arugosin synthesis|upregulation of arugosin formation|up-regulation of arugosin anabolism|up regulation of arugosin biosynthetic process|upregulation of arugosin biosynthetic process|up-regulation of arugosin biosynthesis|positive regulation of arugosin biosynthesis|upregulation of arugosin biosynthesis|activation of arugosin anabolism|upregulation of arugosin synthesis|upregulation of arugosin anabolism|up regulation of arugosin formation|activation of arugosin formation|activation of arugosin biosynthetic process|up-regulation of arugosin biosynthetic process|activation of arugosin synthesis|up-regulation of arugosin synthesis|up regulation of arugosin synthesis|positive regulation of arugosin anabolism|positive regulation of arugosin formation|activation of arugosin biosynthesis|up regulation of arugosin anabolism							di	2012-05-21T05:48:11Z					biological_process											owl:Class	
GO:1900626	biolink:NamedThing	regulation of arugosin biosynthetic process	Any process that modulates the frequency, rate or extent of arugosin biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of arugosin synthesis|regulation of arugosin formation|regulation of arugosin biosynthesis|regulation of arugosin anabolism							di	2012-05-21T05:47:39Z					biological_process											owl:Class	
GO:1900889	biolink:NamedThing	positive regulation of pentadecane biosynthetic process	Any process that activates or increases the frequency, rate or extent of pentadecane biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	up regulation of pentadecane anabolism|activation of pentadecane synthesis|positive regulation of pentadecane synthesis|up regulation of pentadecane synthesis|upregulation of pentadecane formation|positive regulation of pentadecane formation|up regulation of pentadecane biosynthesis|up-regulation of pentadecane biosynthesis|activation of pentadecane formation|up-regulation of pentadecane formation|positive regulation of pentadecane biosynthesis|activation of pentadecane anabolism|positive regulation of pentadecane anabolism|up-regulation of pentadecane synthesis|upregulation of pentadecane biosynthesis|up regulation of pentadecane biosynthetic process|upregulation of pentadecane anabolism|up-regulation of pentadecane anabolism|activation of pentadecane biosynthesis|activation of pentadecane biosynthetic process|upregulation of pentadecane biosynthetic process|up regulation of pentadecane formation|up-regulation of pentadecane biosynthetic process|upregulation of pentadecane synthesis							tt	2012-06-13T03:04:04Z					biological_process											owl:Class	
GO:1902126	biolink:NamedThing	(+)-pinoresinol biosynthetic process	The chemical reactions and pathways resulting in the formation of (+)-pinoresinol.	tmpzr1t_l9r_go_relaxed.owl	(+)-pinoresinol synthesis|(+)-pinoresinol anabolism|(+)-pinoresinol formation|(+)-pinoresinol biosynthesis							ms	2013-05-21T08:49:28Z					biological_process											owl:Class	
GO:0017181	biolink:NamedThing	peptidyl-diphthine catabolic process	The chemical reactions and pathways resulting in the breakdown of peptidyl-diphthine, a modified histidine residue.	tmpzr1t_l9r_go_relaxed.owl	peptidyl-diphthine breakdown|peptidyl-diphthine degradation|peptidyl-diphthine catabolism													biological_process											owl:Class	
GO:0008903	biolink:NamedThing	hydroxypyruvate isomerase activity	Catalysis of the reaction: 3-hydroxypyruvate = 2-hydroxy-3-oxopropanoate.	tmpzr1t_l9r_go_relaxed.owl	hydroxypyruvate ketol-isomerase activity|hydroxypyruvate aldose-ketose-isomerase activity				MetaCyc:RXN0-305|RHEA:11952|KEGG_REACTION:R01394|EC:5.3.1.22									molecular_function											owl:Class	
GO:0016861	biolink:NamedThing	intramolecular oxidoreductase activity, interconverting aldoses and ketoses	Catalysis of an oxidation-reduction (redox) reaction in which the hydrogen donor and acceptor, which is an aldose or a ketose, are the same molecule, and no oxidized product appears.	tmpzr1t_l9r_go_relaxed.owl	intramolecular isomerase activity, interconverting aldoses and ketoses				EC:5.3.1.-									molecular_function											owl:Class	
GO:0047595	biolink:NamedThing	6-hydroxynicotinate reductase activity	Catalysis of the reaction: 1,4,5,6-tetrahydro-6-oxonicotinate + oxidized ferredoxin = 6-hydroxynicotinate + reduced ferredoxin.	tmpzr1t_l9r_go_relaxed.owl	6-hydroxynicotinic reductase activity|1,4,5,6-tetrahydro-6-oxonicotinate:ferredoxin oxidoreductase activity|HNA reductase activity|6-oxotetrahydro-nicotinate dehydrogenase activity|6-oxotetrahydronicotinate dehydrogenase activity|6-oxo-1,4,5,6-tetrahydronicotinate:ferredoxin oxidoreductase activity				RHEA:17225|MetaCyc:6-HYDROXYNICOTINATE-REDUCTASE-RXN|EC:1.3.7.1									molecular_function											owl:Class	
GO:0016636	biolink:NamedThing	oxidoreductase activity, acting on the CH-CH group of donors, iron-sulfur protein as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces an iron-sulfur protein.	tmpzr1t_l9r_go_relaxed.owl	oxidoreductase activity, acting on the CH-CH group of donors, iron-sulphur protein as acceptor				EC:1.3.7.-									molecular_function											owl:Class	
GO:0031499	biolink:NamedThing	TRAMP complex	A multiprotein complex having distributive polyadenylation activity of a variety of RNA substrates including hypomodified and incorrectly folded tRNAs, pre-snRNAs, pre-snoRNAs, incorrectly spliced or processed pre-mRNAs, cryptic unstable transcripts (CUTs), pre-rRNAs and rRNA fragments released as part of rRNA processing. In S. cerevisiae, the complex consists of either Pap2 (also known as Trf4) or Trf5, Air1 or Air2, and Mtr4, and is involved in RNA 3'-end processing and in RNA surveillance and quality control.	tmpzr1t_l9r_go_relaxed.owl	Trf4 poly(A) polymerase complex|TRAMP5 complex|Trf4p-Air2p-Mtr4p polyadenylation complex|Trf4 complex|TRAMP4 complex				Wikipedia:TRAMP_complex									cellular_component											owl:Class	
GO:0110053	biolink:NamedThing	regulation of actin filament organization	Any process that modulates the frequency, rate or extent of actin filament organization.	tmpzr1t_l9r_go_relaxed.owl								kmv	2017-09-20T19:52:57Z					biological_process											owl:Class	
GO:0050536	biolink:NamedThing	(S)-N-acetyl-1-phenylethylamine hydrolase activity	Catalysis of the reaction: N-acetylphenylethylamine + H(2)O = acetate + phenylethylamine.	tmpzr1t_l9r_go_relaxed.owl	(S)-N-acetyl-1-phenylethylamine amidohydrolase activity|(S)-N-acetylphenylethylamine:H2O hydrolase activity				EC:3.5.1.85|KEGG_REACTION:R07301|RHEA:23952|MetaCyc:3.5.1.85-RXN									molecular_function											owl:Class	
GO:0060517	biolink:NamedThing	epithelial cell proliferation involved in prostatic bud elongation	The multiplication of epithelial cells, contributing to the expansion of the primary prostatic bud.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1900903	biolink:NamedThing	negative regulation of hexadecanal biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of hexadecanal biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	inhibition of hexadecanal biosynthesis|down-regulation of hexadecanal anabolism|down-regulation of palmitaldehyde biosynthetic process|down regulation of hexadecanal synthesis|inhibition of hexadecanal synthesis|down-regulation of hexadecanal biosynthetic process|negative regulation of palmitaldehyde biosynthetic process|negative regulation of hexadecanal formation|down regulation of hexadecanal biosynthesis|down-regulation of palmitaldehyde biosynthesis|negative regulation of hexadecanal biosynthesis|downregulation of hexadecanal biosynthetic process|down regulation of hexadecanal anabolism|downregulation of palmitaldehyde biosynthetic process|negative regulation of palmitaldehyde biosynthesis|inhibition of hexadecanal anabolism|downregulation of palmitaldehyde biosynthesis|inhibition of palmitaldehyde biosynthetic process|negative regulation of hexadecanal anabolism|down-regulation of hexadecanal biosynthesis|inhibition of hexadecanal formation|downregulation of hexadecanal biosynthesis|negative regulation of hexadecanal synthesis|downregulation of hexadecanal formation|down regulation of palmitaldehyde biosynthetic process|down regulation of palmitaldehyde biosynthesis|down regulation of hexadecanal biosynthetic process|downregulation of hexadecanal synthesis|down regulation of hexadecanal formation|down-regulation of hexadecanal formation|inhibition of palmitaldehyde biosynthesis|inhibition of hexadecanal biosynthetic process|downregulation of hexadecanal anabolism|down-regulation of hexadecanal synthesis							tt	2012-06-13T03:33:34Z					biological_process											owl:Class	
GO:1900906	biolink:NamedThing	negative regulation of hexadecanal metabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of hexadecanal metabolic process.	tmpzr1t_l9r_go_relaxed.owl	downregulation of hexadecanal metabolism|down-regulation of hexadecanal metabolic process|negative regulation of hexadecanal metabolism|down-regulation of hexadecanal metabolism|down regulation of hexadecanal metabolism|down regulation of hexadecanal metabolic process|inhibition of hexadecanal metabolism|inhibition of hexadecanal metabolic process|downregulation of hexadecanal metabolic process							tt	2012-06-13T03:35:54Z					biological_process											owl:Class	
GO:1902322	biolink:NamedThing	regulation of methyl-branched fatty acid biosynthetic process	Any process that modulates the frequency, rate or extent of methyl-branched fatty acid biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of methyl-branched fatty acid formation|regulation of methyl-branched fatty acid synthesis|regulation of methyl-branched fatty acid biosynthesis|regulation of methyl-branched fatty acid anabolism							kmv	2013-07-24T20:15:15Z					biological_process											owl:Class	
GO:0070634	biolink:NamedThing	transepithelial ammonium transport	The directed movement of ammonium ions from one side of an epithelium to the other.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-05-06T03:34:43Z					biological_process											owl:Class	
GO:0070633	biolink:NamedThing	transepithelial transport	The directed movement of a substance from one side of an epithelium to the other.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-05-06T03:31:02Z					biological_process											owl:Class	
GO:0031430	biolink:NamedThing	M band	The midline of aligned thick filaments in a sarcomere; location of specific proteins that link thick filaments. Depending on muscle type the M band consists of different numbers of M lines.	tmpzr1t_l9r_go_relaxed.owl	M line|midline|mesophragma|M disc				Wikipedia:Sarcomere#bands									cellular_component											owl:Class	
GO:0042789	biolink:NamedThing	mRNA transcription by RNA polymerase II	The cellular synthesis of messenger RNA (mRNA) from a DNA template by RNA polymerase II, originating at an RNA polymerase II promoter.	tmpzr1t_l9r_go_relaxed.owl	mRNA transcription from Pol II promoter|mRNA transcription from RNA polymerase II promoter	https://github.com/geneontology/go-ontology/issues/14854												biological_process											owl:Class	
GO:0009299	biolink:NamedThing	mRNA transcription	The cellular synthesis of messenger RNA (mRNA) from a DNA template.	tmpzr1t_l9r_go_relaxed.owl	mRNA synthesis|cellular mRNA transcription|mRNA biosynthesis|mRNA biosynthetic process											GO:0061023		biological_process											owl:Class	
GO:0019637	biolink:NamedThing	organophosphate metabolic process	The chemical reactions and pathways involving organophosphates, any phosphate-containing organic compound.	tmpzr1t_l9r_go_relaxed.owl	organophosphate metabolism													biological_process											owl:Class	
GO:0016894	biolink:NamedThing	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters	Catalysis of the hydrolysis of ester linkages within nucleic acids by creating internal breaks to yield 3'-phosphomonoesters.	tmpzr1t_l9r_go_relaxed.owl	endoribonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters|3'-endonuclease activity				EC:3.1.31.-	Note that this activity can catalyze cleavage of DNA or RNA.								molecular_function											owl:Class	
GO:0046584	biolink:NamedThing	enniatin metabolic process	The chemical reactions and pathways involving enniatins, any of various cyclodepsipeptide antibiotics from Fusarium species that function as ionophores.	tmpzr1t_l9r_go_relaxed.owl	enniatin metabolism													biological_process											owl:Class	
GO:0031621	biolink:NamedThing	negative regulation of fever generation	Any process that stops, prevents, or reduces the rate or extent of fever generation.	tmpzr1t_l9r_go_relaxed.owl	inhibition of fever|downregulation of fever|down regulation of fever|down-regulation of fever|negative regulation of pyrexia													biological_process											owl:Class	
GO:0031651	biolink:NamedThing	negative regulation of heat generation	Any process that stops, prevents, or reduces the rate or extent of heat generation.	tmpzr1t_l9r_go_relaxed.owl	inhibition of heat generation|downregulation of heat generation|down regulation of heat generation|down-regulation of heat generation													biological_process											owl:Class	
GO:0046938	biolink:NamedThing	phytochelatin biosynthetic process	The chemical reactions and pathways resulting in the formation of phytochelatins, any of a group of peptides that bind metals (Cd, Zn, Cu, Pb, Hg) in thiolate coordination complexes. The structure is of the type (gamma-glutamyl-cysteinyl)n-glycine, where n is 2 to 11.	tmpzr1t_l9r_go_relaxed.owl	phytochelatin synthesis|phytochelatin biosynthesis|phytochelatin anabolism|cadystin biosynthetic process|phytochelatin formation													biological_process											owl:Class	
GO:0046937	biolink:NamedThing	phytochelatin metabolic process	The chemical reactions and pathways involving phytochelatins, any of a group of peptides that bind metals (Cd, Zn, Cu, Pb, Hg) in thiolate coordination complexes. The structure is of the type (gamma-glutamyl-cysteinyl)n-glycine, where n is 2 to 11.	tmpzr1t_l9r_go_relaxed.owl	phytochelatin metabolism|cadystin metabolism|cadystin metabolic process													biological_process											owl:Class	
GO:0050996	biolink:NamedThing	positive regulation of lipid catabolic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of lipids.	tmpzr1t_l9r_go_relaxed.owl	stimulation of lipid catabolic process|upregulation of lipid catabolic process|up-regulation of lipid catabolic process|activation of lipid catabolic process|positive regulation of lipid breakdown|up regulation of lipid catabolic process|positive regulation of lipid catabolism|positive regulation of lipid degradation													biological_process											owl:Class	
GO:0010108	biolink:NamedThing	detection of glutamine	The series of events in which a glutamine stimulus is received by a cell and converted into a molecular signal.	tmpzr1t_l9r_go_relaxed.owl	glutamine sensing|glutamine detection|glutamine perception													biological_process											owl:Class	
GO:2000289	biolink:NamedThing	regulation of photoreceptor cell axon guidance	Any process that modulates the frequency, rate or extent of photoreceptor cell axon guidance.	tmpzr1t_l9r_go_relaxed.owl	regulation of photoreceptor cell axon pathfinding							mah	2010-12-17T10:04:35Z					biological_process											owl:Class	
GO:0046177	biolink:NamedThing	D-gluconate catabolic process	The chemical reactions and pathways resulting in the breakdown of D-gluconate, the anion of D-gluconic acid, the aldonic acid derived from glucose.	tmpzr1t_l9r_go_relaxed.owl	D-gluconate degradation|D-gluconate breakdown|D-gluconate catabolism				MetaCyc:GLUCONSUPER-PWY									biological_process											owl:Class	
GO:0140270	biolink:NamedThing	gluconate import across plasma membrane	The directed movement of gluconate from outside of a cell, across the plasma membrane and into the cytosol.	tmpzr1t_l9r_go_relaxed.owl								pg	2018-10-01T08:47:35Z					biological_process											owl:Class	
GO:0030410	biolink:NamedThing	nicotianamine synthase activity	Catalysis of the reaction: 3 S-adenosyl-L-methionine(1+) = 3 S-methyl-5'-thioadenosine + 3 H(+) + nicotianamine.	tmpzr1t_l9r_go_relaxed.owl	S-adenosyl-L-methionine:S-adenosyl-L-methionine:S-adenosyl-L-methionine 3-amino-3-carboxypropyltransferase activity				MetaCyc:2.5.1.43-RXN|RHEA:16481|EC:2.5.1.43|KEGG_REACTION:R00075									molecular_function											owl:Class	
GO:0061474	biolink:NamedThing	phagolysosome membrane	The lipid bilayer surrounding a phagolysosome.	tmpzr1t_l9r_go_relaxed.owl								dph	2012-11-06T12:26:18Z					cellular_component											owl:Class	
GO:0030670	biolink:NamedThing	phagocytic vesicle membrane	The lipid bilayer surrounding a phagocytic vesicle.	tmpzr1t_l9r_go_relaxed.owl	phagosome membrane													cellular_component											owl:Class	
GO:0097291	biolink:NamedThing	renal phosphate ion absorption	A renal system process in which phosphate ions are taken up from the collecting ducts and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures.	tmpzr1t_l9r_go_relaxed.owl	renal phosphate absorption							pr	2012-04-25T03:34:48Z					biological_process											owl:Class	
GO:0070293	biolink:NamedThing	renal absorption	A renal system process in which water, ions, glucose and proteins are taken up from the collecting ducts, glomerulus and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures (e.g. protein absorption is observed in nephrocytes in Drosophila, see PMID:23264686).	tmpzr1t_l9r_go_relaxed.owl	renal reabsorption|nephron absorption													biological_process											owl:Class	
GO:1904332	biolink:NamedThing	negative regulation of error-prone translesion synthesis	Any process that stops, prevents or reduces the frequency, rate or extent of error-prone translesion synthesis.	tmpzr1t_l9r_go_relaxed.owl	inhibition of mutagenic PRR|down-regulation of mutagenic postreplication DNA repair|inhibition of error-prone translesion synthesis|down regulation of mutagenic PRR|inhibition of mutagenic postreplication DNA repair|down-regulation of error-prone translesion synthesis|downregulation of mutagenic PRR|negative regulation of mutagenic postreplication DNA repair|down-regulation of error-prone postreplication DNA repair|inhibition of error-prone postreplication DNA repair|down-regulation of mutagenic PRR|negative regulation of mutagenic PRR|downregulation of error-prone translesion synthesis|downregulation of error-prone postreplication DNA repair|downregulation of mutagenic postreplication DNA repair|down regulation of mutagenic postreplication DNA repair|down regulation of error-prone postreplication DNA repair|negative regulation of error-prone postreplication DNA repair|down regulation of error-prone translesion synthesis							kmv	2015-06-11T16:24:53Z					biological_process											owl:Class	
GO:0080187	biolink:NamedThing	floral organ senescence	An organ senescence that has as a participant a floral organ.	tmpzr1t_l9r_go_relaxed.owl						Includes senescence of petals, sepals, anthers, and any other plant organ that is part of a flower. Floral organ senescence may follow pollination. In some flowers, the organs of the corolla abscise before they senesce.		dhl	2012-03-09T04:08:50Z					biological_process											owl:Class	
GO:0090552	biolink:NamedThing	unicellular trichome apex	A cell projection part that is the apical most portion of a unicellular trichome.	tmpzr1t_l9r_go_relaxed.owl								tb	2013-04-25T11:56:56Z					cellular_component											owl:Class	
GO:2000393	biolink:NamedThing	negative regulation of lamellipodium morphogenesis	Any process that stops, prevents or reduces the frequency, rate or extent of lamellipodium morphogenesis.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of lamellipodium organization							mah	2011-02-22T11:19:25Z					biological_process											owl:Class	
GO:0014723	biolink:NamedThing	regulation of skeletal muscle contraction by modulation of calcium ion sensitivity of myofibril	Any process that modulates the frequency, rate or extent of skeletal muscle contraction by changing calcium ion binding affinity of the myofibril.	tmpzr1t_l9r_go_relaxed.owl	regulation of calcium ion sensitivity of myofibril involved in skeletal muscle contraction													biological_process											owl:Class	
GO:0014722	biolink:NamedThing	regulation of skeletal muscle contraction by calcium ion signaling	Any process that modulates the frequency, rate or extent of skeletal muscle contraction by changing the calcium ion signals that trigger contraction.	tmpzr1t_l9r_go_relaxed.owl	regulation of skeletal muscle contraction by calcium ion signalling													biological_process											owl:Class	
GO:0030895	biolink:NamedThing	apolipoprotein B mRNA editing enzyme complex	Protein complex that mediates editing of the mRNA encoding apolipoprotein B; catalyzes the deamination of C to U (residue 6666 in the human mRNA). Contains a catalytic subunit, APOBEC-1, and other proteins (e.g. human ASP; rat ASP and KSRP).	tmpzr1t_l9r_go_relaxed.owl	APOBEC|apoB mRNA editing enzyme complex													cellular_component											owl:Class	
GO:0035582	biolink:NamedThing	sequestering of BMP in extracellular matrix	Confining a bone morphogenetic protein (BMP) to the extracellular matrix (ECM), such that it is separated from other components of the signaling pathway, including its cell surface receptor. Bone morphogenetic proteins (BMPs) are secreted as homodimers, non-covalently associated with N-terminal pro-peptides, and are targeted to the extracellular matrix through interaction with matrix proteins.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of bone morphogenetic protein signaling pathway by extracellular matrix sequestering of bone morphogenetic protein|negative regulation of BMP signalling pathway by extracellular matrix sequestering of BMP|negative regulation of BMP signaling pathway by extracellular sequestering of BMP|BMP sequestration in the ECM					Confining BMP in the extracellular matrix may be achieved by binding BMP directly, or by binding to members of a BMP-containing complex.		bf	2010-10-12T03:12:45Z					biological_process											owl:Class	
GO:0030514	biolink:NamedThing	negative regulation of BMP signaling pathway	Any process that stops, prevents, or reduces the frequency, rate or extent of the BMP signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of bone morphogenetic protein signalling pathway|negative regulation of decapentaplegic receptor signaling pathway|inhibition of BMP signaling pathway|negative regulation of BMP signalling pathway|negative regulation of BMP receptor signaling pathway|negative regulation of decapentaplegic receptor signalling pathway|downregulation of BMP signaling pathway|down regulation of BMP signaling pathway|down-regulation of BMP signaling pathway|negative regulation of bone morphogenetic protein signaling pathway|negative regulation of decapentaplegic signaling pathway							tb	2009-11-13T10:51:30Z			GO:0090099		biological_process											owl:Class	
GO:2000263	biolink:NamedThing	regulation of blood coagulation, extrinsic pathway	Any process that modulates the frequency, rate or extent of blood coagulation, extrinsic pathway.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-11-23T11:44:35Z					biological_process											owl:Class	
GO:0050858	biolink:NamedThing	negative regulation of antigen receptor-mediated signaling pathway	Any process that stops, prevents, or reduces the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a B- or T cell.	tmpzr1t_l9r_go_relaxed.owl	down regulation of antigen receptor-mediated signaling pathway|down-regulation of antigen receptor-mediated signaling pathway|downregulation of antigen receptor-mediated signaling pathway|inhibition of antigen receptor-mediated signaling pathway|negative regulation of antigen receptor mediated signalling pathway													biological_process											owl:Class	
GO:1901141	biolink:NamedThing	regulation of lignin biosynthetic process	Any process that modulates the frequency, rate or extent of lignin biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of lignin formation|regulation of lignin biosynthesis|regulation of lignin synthesis|regulation of lignin anabolism							tb	2012-07-12T09:53:09Z					biological_process											owl:Class	
GO:0009298	biolink:NamedThing	GDP-mannose biosynthetic process	The chemical reactions and pathways resulting in the formation of GDP-mannose, a substance composed of mannose in glycosidic linkage with guanosine diphosphate.	tmpzr1t_l9r_go_relaxed.owl	GDP-mannose biosynthesis|GDP-mannose synthesis|GDP-mannose formation|GDP-mannose anabolism													biological_process											owl:Class	
GO:0051692	biolink:NamedThing	cellular oligosaccharide catabolic process	The chemical reactions and pathways resulting in the breakdown of oligosaccharides, molecules with between two and (about) 20 monosaccharide residues connected by glycosidic linkages, as carried out by individual cells.	tmpzr1t_l9r_go_relaxed.owl	cellular oligosaccharide catabolism|cellular oligosaccharide degradation|cellular oligosaccharide breakdown													biological_process											owl:Class	
GO:0034232	biolink:NamedThing	ascospore wall chitin catabolic process	The chemical reactions and pathways resulting in the breakdown of ascospore wall chitin, a linear polysaccharide consisting of P-1,4-linked N-acetyl-D-glucosamine residues, found in the walls of ascospores.	tmpzr1t_l9r_go_relaxed.owl	ascospore wall chitin degradation|ascospore wall chitin catabolism|ascospore wall chitin breakdown													biological_process											owl:Class	
GO:0044347	biolink:NamedThing	cell wall polysaccharide catabolic process	The chemical reactions and pathways resulting in the breakdown of cell wall polysaccharides.	tmpzr1t_l9r_go_relaxed.owl	cell wall polysaccharide breakdown							jl	2011-07-28T01:24:57Z					biological_process											owl:Class	
GO:0102811	biolink:NamedThing	geraniol 10-hydroxylase activity	Catalysis of the reaction: geraniol + O2 + NADPH + H+ <=> (6E)-8-hydroxygeraniol + NADP + H2O.	tmpzr1t_l9r_go_relaxed.owl					EC:1.14.14.83|MetaCyc:RXN-8197|RHEA:32495									molecular_function											owl:Class	
GO:1904605	biolink:NamedThing	positive regulation of advanced glycation end-product receptor activity	Any process that activates or increases the frequency, rate or extent of advanced glycation end-product receptor activity.	tmpzr1t_l9r_go_relaxed.owl	upregulation of advanced glycation end-product receptor activity|activation of RAGE activity|upregulation of RAGE activity|up-regulation of RAGE activity|up regulation of advanced glycation end-product receptor activity|up regulation of AGE receptor activity|activation of AGE receptor activity|positive regulation of AGE receptor activity|positive regulation of RAGE activity|up regulation of RAGE activity|up-regulation of advanced glycation end-product receptor activity|upregulation of AGE receptor activity|activation of advanced glycation end-product receptor activity|up-regulation of AGE receptor activity							krc	2015-08-26T16:25:02Z					biological_process											owl:Class	
GO:1901822	biolink:NamedThing	delta-carotene metabolic process	The chemical reactions and pathways involving delta-carotene.	tmpzr1t_l9r_go_relaxed.owl	delta-carotene metabolism							yaf	2013-01-22T11:17:29Z					biological_process											owl:Class	
GO:0102355	biolink:NamedThing	2-oxo-3-(5-oxofuran-2-ylidene)propanoate lactonase activity	Catalysis of the reaction: 2-oxo-3-(5-oxofuran-2-ylidene)propanoate + H2O <=> 3-maleylpyruvate + H+.	tmpzr1t_l9r_go_relaxed.owl					EC:3.1.1.91|RHEA:33967|MetaCyc:RXN-13371									molecular_function											owl:Class	
GO:0031063	biolink:NamedThing	regulation of histone deacetylation	Any process that modulates the frequency, rate or extent of the removal of acetyl groups from histones.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:2000175	biolink:NamedThing	negative regulation of pro-T cell differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of pro-T cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of pro-T lymphocyte differentiation							mah	2010-10-11T10:24:33Z					biological_process											owl:Class	
GO:2000174	biolink:NamedThing	regulation of pro-T cell differentiation	Any process that modulates the frequency, rate or extent of pro-T cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	regulation of pro-T lymphocyte differentiation							mah	2010-10-11T10:24:30Z					biological_process											owl:Class	
GO:0006121	biolink:NamedThing	mitochondrial electron transport, succinate to ubiquinone	The transfer of electrons from succinate to ubiquinone that occurs during oxidative phosphorylation, mediated by the multisubunit enzyme known as complex II.	tmpzr1t_l9r_go_relaxed.owl	complex II (succinate to ubiquinone)|mitochondrial electron transport, succinate to coenzyme Q|oxidative phosphorylation, succinate to ubiquinone													biological_process											owl:Class	
GO:0048793	biolink:NamedThing	pronephros development	The process whose specific outcome is the progression of the pronephros over time, from its formation to the mature structure. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life.	tmpzr1t_l9r_go_relaxed.owl	pronephric kidney development													biological_process											owl:Class	
GO:0015012	biolink:NamedThing	heparan sulfate proteoglycan biosynthetic process	The chemical reactions and pathways resulting in the formation of the heparan sulfate proteoglycan, a glycosaminoglycan with repeat unit consisting of alternating alpha-(1->4)-linked hexuronic acid and glucosamine residues; the former are a mixture of sulfated and nonsulfated D-glucuronic acid and L-iduronic acid; the L-iduronic acid is either sulfated or acetylated on its amino group as well as being sulfated on one of its hydroxyl groups; heparan sulfate chains are covalently linked to peptidyl-serine by a glycosidic attachment through the trisaccharide galactosyl-galactosyl-xylosyl to serine residues.	tmpzr1t_l9r_go_relaxed.owl	heparan sulphate proteoglycan biosynthesis|heparan sulfate proteoglycan synthesis|heparan sulfate proteoglycan formation|heparan sulfate proteoglycan biosynthesis|heparin proteoglycan biosynthetic process|heparan sulfate proteoglycan anabolism|heparan sulphate proteoglycan biosynthetic process				RESID:AA0210									biological_process											owl:Class	
GO:0098916	biolink:NamedThing	anterograde trans-synaptic signaling	Cell-cell signaling from pre to post-synapse, across the synaptic cleft.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0015498	biolink:NamedThing	pantothenate:sodium symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: pantothenate(out) + Na+(out) = pantothenate(in) + Na+(in).	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0097247	biolink:NamedThing	epigallocatechin 3-gallate binding	Binding to epigallocatechin 3-gallate, a compound that is a gallic acid ester of a catechin.	tmpzr1t_l9r_go_relaxed.owl	EGCG binding|catechin gallate binding							pr	2012-02-17T03:55:05Z					molecular_function											owl:Class	
GO:1901093	biolink:NamedThing	regulation of protein homotetramerization	Any process that modulates the frequency, rate or extent of protein homotetramerization.	tmpzr1t_l9r_go_relaxed.owl	regulation of protein homotetramer biosynthetic process|regulation of protein homotetramer assembly|regulation of protein homotetramer biosynthesis|regulation of protein homotetramer formation							pm	2012-07-06T12:57:33Z					biological_process											owl:Class	
GO:1901090	biolink:NamedThing	regulation of protein tetramerization	Any process that modulates the frequency, rate or extent of protein tetramerization.	tmpzr1t_l9r_go_relaxed.owl	regulation of protein tetramer biosynthesis|regulation of protein tetramer biosynthetic process|regulation of protein tetramer formation|regulation of protein tetramer assembly							pm	2012-07-06T12:51:00Z					biological_process											owl:Class	
GO:0050337	biolink:NamedThing	thiosulfate-thiol sulfurtransferase activity	Catalysis of the reaction: thiosulfate + 2 glutathione = sulfite + glutathione disulfide + sulfide.	tmpzr1t_l9r_go_relaxed.owl	sulfane sulfurtransferase activity|thiosulfate:thiol sulfurtransferase activity|thiosulphate-thiol sulphurtransferase activity|glutathione-dependent thiosulfate reductase activity|sulfane reductase activity				Reactome:R-HSA-1655879|RHEA:14505|EC:2.8.1.3|MetaCyc:THIOSULFATE--THIOL-SULFURTRANSFERASE-RXN									molecular_function											owl:Class	
GO:0038188	biolink:NamedThing	cholecystokinin signaling pathway	The series of molecular signals generated as a consequence of cholecystokinin binding to a receptor on the surface of the cell, and proceeding with the activated receptor transmitting the signal to a heterotrimeric G-protein complex to initiate a change in cell activity. Ends with regulation of a downstream cellular process, e.g. transcription.	tmpzr1t_l9r_go_relaxed.owl	CCK signaling|cholecystokinin receptor signaling pathway				Wikipedia:Cholecystokinin			bf	2013-07-01T13:05:46Z					biological_process											owl:Class	
GO:0072331	biolink:NamedThing	signal transduction by p53 class mediator	An intracellular signaling process that is induced by the cell cycle regulator phosphoprotein p53 or an equivalent protein.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-11-03T01:32:59Z					biological_process											owl:Class	
GO:0033130	biolink:NamedThing	acetylcholine receptor binding	Binding to an acetylcholine receptor.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1904663	biolink:NamedThing	regulation of N-terminal peptidyl-methionine acetylation	Any process that modulates the frequency, rate or extent of N-terminal peptidyl-methionine acetylation.	tmpzr1t_l9r_go_relaxed.owl								vw	2015-09-07T19:18:49Z					biological_process											owl:Class	
GO:1900708	biolink:NamedThing	negative regulation of tensidol A biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of tensidol A biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	down regulation of tensidol A anabolism|down regulation of tensidol A formation|negative regulation of tensidol A biosynthesis|downregulation of tensidol A synthesis|inhibition of tensidol A biosynthesis|down-regulation of tensidol A biosynthetic process|down-regulation of tensidol A biosynthesis|down-regulation of tensidol A synthesis|negative regulation of tensidol A synthesis|downregulation of tensidol A biosynthesis|inhibition of tensidol A synthesis|downregulation of tensidol A formation|inhibition of tensidol A biosynthetic process|downregulation of tensidol A anabolism|inhibition of tensidol A formation|inhibition of tensidol A anabolism|negative regulation of tensidol A formation|down-regulation of tensidol A formation|downregulation of tensidol A biosynthetic process|down regulation of tensidol A biosynthetic process|negative regulation of tensidol A anabolism|down-regulation of tensidol A anabolism|down regulation of tensidol A synthesis|down regulation of tensidol A biosynthesis							di	2012-05-22T05:02:04Z					biological_process											owl:Class	
GO:0034168	biolink:NamedThing	negative regulation of toll-like receptor 10 signaling pathway	Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 10 signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of TLR10 signaling pathway|negative regulation of toll-like receptor 10 signalling pathway													biological_process											owl:Class	
GO:1990806	biolink:NamedThing	ligand-gated ion channel signaling pathway	A series of molecular signals initiated by activation of a ligand-gated ion channel on the surface of a cell. The pathway begins with binding of an extracellular ligand to a ligand-gated ion channel and ends with a molecular function that directly regulates a downstream cellular process, e.g. transcription.	tmpzr1t_l9r_go_relaxed.owl	ligand-gated ion channel signalling pathway							bhm	2015-07-20T12:09:56Z					biological_process											owl:Class	
GO:0004629	biolink:NamedThing	phospholipase C activity	Catalysis of the reaction: a phospholipid + H2O = 1,2-diacylglycerol + a phosphatidate.	tmpzr1t_l9r_go_relaxed.owl	lecithinase C activity|phosphatidase C|lipophosphodiesterase C				Reactome:R-HSA-114689|Reactome:R-HSA-114688|Reactome:R-HSA-5362553|Reactome:R-HSA-398193|MetaCyc:PHOSPHOLIPASE-C-RXN|EC:3.1.4.3|Reactome:R-HSA-1112666|Reactome:R-HSA-399998							GO:0042298		molecular_function											owl:Class	
GO:0008081	biolink:NamedThing	phosphoric diester hydrolase activity	Catalysis of the hydrolysis of a phosphodiester to give a phosphomonoester and a free hydroxyl group.	tmpzr1t_l9r_go_relaxed.owl	phosphodiesterase				Reactome:R-HSA-5693578|EC:3.1.4.-							GO:0004434|GO:0016792		molecular_function											owl:Class	
GO:0002682	biolink:NamedThing	regulation of immune system process	Any process that modulates the frequency, rate, or extent of an immune system process.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0102494	biolink:NamedThing	GA20 2,3-desaturase activity	Catalysis of the reaction: gibberellin A20 + O2 + a reduced electron acceptor <=> gibberellin A5 + 2 H2O + an oxidized electron acceptor.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-14317									molecular_function											owl:Class	
GO:0048073	biolink:NamedThing	regulation of eye pigmentation	Any process that modulates the frequency, rate or extent of establishment of a pattern of pigment in the eye of an organism.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1901799	biolink:NamedThing	negative regulation of proteasomal protein catabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of proteasomal protein catabolic process.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of proteasomal protein catabolic process|inhibition of proteasome-mediated protein catabolic process|negative regulation of proteasome-mediated protein catabolism|down regulation of proteasomal protein catabolic process|downregulation of proteasome-mediated protein catabolism|down regulation of proteasome-mediated protein catabolism|negative regulation of proteasome-mediated protein catabolic process|downregulation of proteasome-mediated protein catabolic process|downregulation of proteasomal protein catabolic process|down regulation of proteasome-mediated protein catabolic process|inhibition of proteasomal protein catabolic process|down-regulation of proteasome-mediated protein catabolism|inhibition of proteasome-mediated protein catabolism|down-regulation of proteasome-mediated protein catabolic process							rl	2013-01-21T20:10:54Z					biological_process											owl:Class	
GO:0034955	biolink:NamedThing	2,3-dihydroxydiphenyl ether dioxygenase activity	Catalysis of the reaction: 2,3-dihydroxydiphenyl ether + O2 + H2O = 2-hydroxymuconate + phenol.	tmpzr1t_l9r_go_relaxed.owl					EC:1.13.11.-|UM-BBD_reactionID:r1451									molecular_function											owl:Class	
GO:0016600	biolink:NamedThing	flotillin complex	A protein complex that contains flotillin-1 and flotillin-2, and may contain associated proteins. Flotillins associate into membrane microdomains resembling caveolae.	tmpzr1t_l9r_go_relaxed.owl						See also the cellular component term 'caveola ; GO:0005901'.								cellular_component											owl:Class	
GO:0010992	biolink:NamedThing	ubiquitin recycling	Any process involved in the maintenance of an internal steady state of ubiquitin monomers and free ubiquitin chains at the level of the cell by recycling ubiquitin from proteasome-bound ubiquitinated intermediates.	tmpzr1t_l9r_go_relaxed.owl	ubiquitin homeostasis|regulation of ubiquitin homeostasis							tb	2009-06-03T11:36:55Z			GO:0010993		biological_process											owl:Class	
GO:1900081	biolink:NamedThing	regulation of arginine catabolic process	Any process that modulates the frequency, rate or extent of arginine catabolic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of arginine catabolism|regulation of arginine degradation|regulation of arginine breakdown							pr	2012-02-01T04:04:39Z					biological_process											owl:Class	
GO:0000821	biolink:NamedThing	regulation of arginine metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving arginine, 2-amino-5-(carbamimidamido)pentanoic acid.	tmpzr1t_l9r_go_relaxed.owl	regulation of arginine metabolism													biological_process											owl:Class	
GO:0004923	biolink:NamedThing	leukemia inhibitory factor receptor activity	Combining with leukemia inhibitory factor (LIF) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	leukemia inhibitory factor receptor beta-protein activity|LIF receptor activity											GO:0004899		molecular_function											owl:Class	
GO:0004897	biolink:NamedThing	ciliary neurotrophic factor receptor activity	Combining with ciliary neurotrophic factor (CNTF) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	gp130|CNTF receptor activity													molecular_function											owl:Class	
GO:0090713	biolink:NamedThing	immunological memory process	Any process of the immune system that can contribute to the formation of immunological memory or an immune response based upon activation of immunological memory.	tmpzr1t_l9r_go_relaxed.owl								tb	2016-11-11T12:20:30Z					biological_process											owl:Class	
GO:0060954	biolink:NamedThing	neural crest-derived cardiac glial cell development	The process aimed at the progression of a neural crest-derived cardiac glial cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-09-29T03:14:15Z					biological_process											owl:Class	
GO:0060952	biolink:NamedThing	cardiac glial cell development	The process aimed at the progression of a cardiac glial cell over time, from its formation to the fully functional mature cell.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-09-29T03:09:24Z					biological_process											owl:Class	
GO:0007196	biolink:NamedThing	adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway	The series of molecular signals generated as a consequence of a G protein-coupled glutamate receptor binding to its physiological ligand, where the pathway proceeds with inhibition of adenylyl cyclase and a subsequent decrease in the concentration of cyclic AMP (cAMP).	tmpzr1t_l9r_go_relaxed.owl	metabotropic glutamate receptor, adenylate cyclase inhibiting pathway|inhibition of adenylate cyclase activity by G-protein-coupled glutamate receptor signaling pathway|metabotropic glutamate receptor, adenylyl cyclase inhibiting pathway|inhibition of adenylate cyclase activity by metabotropic glutamate receptor signaling pathway|inhibition of adenylate cyclase activity by metabotropic glutamate receptor signalling pathway|adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway													biological_process											owl:Class	
GO:0007193	biolink:NamedThing	adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway	The series of molecular signals generated as a consequence of a G protein-coupled receptor binding to its physiological ligand, where the pathway proceeds through inhibition of adenylyl cyclase activity and a subsequent decrease in the concentration of cyclic AMP (cAMP).	tmpzr1t_l9r_go_relaxed.owl	G protein signalling, adenylate cyclase inhibiting pathway|G-protein signaling, adenylate cyclase inhibiting pathway|G-protein signalling, adenylate cyclase inhibiting pathway|inhibition of adenylate cyclase activity by G-protein signaling pathway|G protein signaling, adenylyl cyclase inhibiting pathway|G protein signalling, adenylyl cyclase inhibiting pathway|G-protein signaling, adenylyl cyclase inhibiting pathway|G protein signaling, adenylate cyclase inhibiting pathway|adenylate cyclase-inhibiting GPCR signaling pathway|GPCR signaling pathway via inhibition of adenylate cyclase activity|G-protein signalling, adenylyl cyclase inhibiting pathway					This term is intended to cover steps in a GPCR signaling pathway both upstream and downstream of adenylate-cyclase inhibition.								biological_process											owl:Class	
GO:0048319	biolink:NamedThing	axial mesoderm morphogenesis	The process in which the anatomical structures of the axial mesoderm are generated and organized.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0017198	biolink:NamedThing	N-terminal peptidyl-serine acetylation	The acetylation of the N-terminal serine of proteins to form the derivative N-acetyl-L-serine.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0051									biological_process											owl:Class	
GO:0006474	biolink:NamedThing	N-terminal protein amino acid acetylation	The acetylation of the N-terminal amino acid of proteins.	tmpzr1t_l9r_go_relaxed.owl	N(alpha)-terminal acetylation													biological_process											owl:Class	
GO:1904130	biolink:NamedThing	regulation of convergent extension involved in neural plate elongation	Any process that modulates the frequency, rate or extent of convergent extension involved in neural plate elongation.	tmpzr1t_l9r_go_relaxed.owl								dph	2015-04-10T21:13:21Z					biological_process											owl:Class	
GO:0000402	biolink:NamedThing	crossed form four-way junction DNA binding	Binding to a DNA segment containing the crossed form of a four-way junction, also known as a Holliday junction, a structure where two DNA double strands are held together by reciprocal exchange of two of the four strands, one strand each from the two original helices. The crossed form of a four-way junction cannot be diagrammed without any of the strands crossing over, and instead contains a single crossover between two of the strands.	tmpzr1t_l9r_go_relaxed.owl	crossed form Holliday junction binding													molecular_function											owl:Class	
GO:0000400	biolink:NamedThing	four-way junction DNA binding	Binding to a DNA segment containing four-way junctions, also known as Holliday junctions, a structure where two DNA double strands are held together by reciprocal exchange of two of the four strands, one strand each from the two original helices.	tmpzr1t_l9r_go_relaxed.owl	Holliday junction binding|forked DNA binding													molecular_function											owl:Class	
GO:1990198	biolink:NamedThing	ModE complex	A dimeric protein complex containing two ModE subunits. Binds directly to DNA to regulate transcription, and is involved in (positively and negatively) regulating various aspects of molybdenum metabolism.	tmpzr1t_l9r_go_relaxed.owl	ModE dimer							bhm	2013-10-01T07:28:52Z					cellular_component											owl:Class	
GO:0005667	biolink:NamedThing	transcription regulator complex	A protein complex that is capable of associating with DNA by direct binding, or via other DNA-binding proteins or complexes, and regulating transcription.	tmpzr1t_l9r_go_relaxed.owl	nuclear transcription factor complex|cytoplasmic transcription factor complex|transcription factor complex							jl	2013-08-28T12:11:37Z			GO:0044797|GO:0044798		cellular_component											owl:Class	
GO:2000536	biolink:NamedThing	negative regulation of entry of bacterium into host cell	Any process that stops, prevents or reduces the frequency, rate or extent of entry of bacterium into host cell.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of invasion of bacteria into host cell|negative regulation of bacterial entry into host cell							ebc	2011-03-28T09:52:23Z					biological_process											owl:Class	
GO:1901824	biolink:NamedThing	delta-carotene biosynthetic process	The chemical reactions and pathways resulting in the formation of delta-carotene.	tmpzr1t_l9r_go_relaxed.owl	delta-carotene anabolism|delta-carotene formation|delta-carotene biosynthesis|delta-carotene synthesis							yaf	2013-01-22T11:17:38Z					biological_process											owl:Class	
GO:0016120	biolink:NamedThing	carotene biosynthetic process	The chemical reactions and pathways resulting in the formation of carotenes, hydrocarbon carotenoids.	tmpzr1t_l9r_go_relaxed.owl	carotene biosynthesis|carotene anabolism|carotene synthesis|carotene formation													biological_process											owl:Class	
GO:0010956	biolink:NamedThing	negative regulation of calcidiol 1-monooxygenase activity	Any process that decreases the rate, frequency or extent of calcidiol 1-monooxygenase activity. Calcidiol 1-monooxygenase activity is the catalysis of the reaction: calcidiol + NADPH + H+ + O2 = calcitriol + NADP+ + H2O.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-05-06T11:21:34Z					biological_process											owl:Class	
GO:0044484	biolink:NamedThing	envenomation resulting in fibrinolysis in other organism	The process which begins with venom being forced into an organism by the bite or sting of another organism, and ends with fibrinolysis, a process that solubilizes fibrin, chiefly by the proteolytic action of plasmin, in the bloodstream of the bitten/stung organism.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-01-26T03:26:33Z					biological_process											owl:Class	
GO:0044483	biolink:NamedThing	envenomation resulting in impairment of hemostasis in other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the inhibition of the process of hemostasis - the stopping of bleeding or the arrest of the circulation to an organ or part - in the bitten organism.	tmpzr1t_l9r_go_relaxed.owl	envenomation resulting in negative regulation of hemostasis in other organism|envenomation, impairing hemostasis in other organism							jl	2012-01-19T03:15:56Z					biological_process											owl:Class	
GO:1905205	biolink:NamedThing	positive regulation of connective tissue replacement	Any process that activates or increases the frequency, rate or extent of connective tissue replacement.	tmpzr1t_l9r_go_relaxed.owl	upregulation of connective tissue replacement|up regulation of connective tissue replacement|up-regulation of connective tissue replacement|activation of connective tissue replacement							bc	2016-05-17T09:54:35Z					biological_process											owl:Class	
GO:0089703	biolink:NamedThing	L-aspartate transmembrane export from vacuole	The directed movement of L-aspartate out of the vacuole, across the vacuolar membrane.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0070778	biolink:NamedThing	L-aspartate transmembrane transport	The directed movement of L-aspartate across a membrane.	tmpzr1t_l9r_go_relaxed.owl	L-aspartate transport							mah	2009-07-02T01:46:31Z			GO:0089712		biological_process											owl:Class	
GO:0090421	biolink:NamedThing	embryonic meristem initiation	Initiation of a region of tissue in a plant embryo that is composed of one or more undifferentiated cells capable of undergoing mitosis and differentiation.	tmpzr1t_l9r_go_relaxed.owl								tb	2012-04-13T02:52:34Z					biological_process											owl:Class	
GO:0010014	biolink:NamedThing	meristem initiation	Initiation of a region of tissue in a plant that is composed of one or more undifferentiated cells capable of undergoing mitosis and differentiation, thereby effecting growth and development of a plant by giving rise to more meristem or specialized tissue.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1900923	biolink:NamedThing	regulation of glycine import across plasma membrane	Any process that modulates the frequency, rate or extent of glycine import into a cell.	tmpzr1t_l9r_go_relaxed.owl	regulation of glycine import							al	2012-06-13T07:40:11Z					biological_process											owl:Class	
GO:0061679	biolink:NamedThing	Entner-Doudoroff pathway through gluconate	The Entner-Doudoroff pathway that proceeds through a D-gluconate intermediate.	tmpzr1t_l9r_go_relaxed.owl	gluconate pathway							dph	2015-01-16T15:41:22Z					biological_process											owl:Class	
GO:0061678	biolink:NamedThing	Entner-Doudoroff pathway	A cellular carbohydrate catabolic process that converts a carbohydrate to pyruvate and either glyceraldehyde or glyceraldehyde-3 phosphate by dehydration and aldol cleavage via a gluconate or 6-phosphogluconate intermediate.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:Entner-Doudoroff-Pathways			dph	2015-01-16T15:28:25Z					biological_process											owl:Class	
GO:2000525	biolink:NamedThing	positive regulation of T cell costimulation	Any process that activates or increases the frequency, rate or extent of T cell costimulation.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of T lymphocyte costimulation|positive regulation of T-cell costimulation|positive regulation of T-lymphocyte costimulation|positive regulation of T cell co-stimulation|positive regulation of T-cell co-stimulation							ebc	2011-03-23T10:23:36Z					biological_process											owl:Class	
GO:0050870	biolink:NamedThing	positive regulation of T cell activation	Any process that activates or increases the frequency, rate or extent of T cell activation.	tmpzr1t_l9r_go_relaxed.owl	up regulation of T cell activation|positive regulation of T-cell activation|stimulation of T cell activation|upregulation of T cell activation|positive regulation of T-lymphocyte activation|up-regulation of T cell activation|activation of T cell activation|positive regulation of T lymphocyte activation													biological_process											owl:Class	
GO:0042188	biolink:NamedThing	1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane catabolic process	The chemical reactions and pathways resulting in the breakdown of 1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane (DDT), a chlorinated broad spectrum contact insecticide.	tmpzr1t_l9r_go_relaxed.owl	DDT catabolic process|1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane degradation|1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane breakdown|1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane catabolism|DDT catabolism													biological_process											owl:Class	
GO:0018977	biolink:NamedThing	1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane metabolic process	The chemical reactions and pathways involving 1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane (DDT), a chlorinated broad spectrum contact insecticide.	tmpzr1t_l9r_go_relaxed.owl	DDT metabolism|1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane metabolism|DDT metabolic process				UM-BBD_pathwayID:ddt									biological_process											owl:Class	
GO:0075324	biolink:NamedThing	negative regulation of oomycete sporangium development	Any process that stops, prevents, or reduces the frequency, rate or extent of oomycete sporangium development, a process that leads to the formation of oomycete sporangium, a single-celled or many-celled structure that germinates directly to form an infection hypha or differentiate, through specialized cleavage vesicles, into between 10 and 30 zoospores, which is laterally flagellated.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0086017	biolink:NamedThing	Purkinje myocyte action potential	An action potential that occurs in a Purkinje myocyte.	tmpzr1t_l9r_go_relaxed.owl								tb	2011-11-10T08:58:56Z					biological_process											owl:Class	
GO:0008443	biolink:NamedThing	phosphofructokinase activity	Catalysis of the transfer of a phosphate group, usually from ATP, to a phosphofructose substrate molecule.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0102036	biolink:NamedThing	methyltetrahydrofolate:corrinoid/iron-sulfur protein methyltransferase activity	Catalysis of the reaction: a tetrahydrofolate + a [methyl-Co(III) corrinoid Fe-S protein] <=> an N5-methyl-tetrahydrofolate + a [Co(I) corrinoid Fe-S protein].	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:METHCOCLTH-RXN|EC:2.1.1.258|RHEA:45200									molecular_function											owl:Class	
GO:1903002	biolink:NamedThing	positive regulation of lipid transport across blood-brain barrier	Any process that activates or increases the frequency, rate or extent of lipid transport across blood-brain barrier.	tmpzr1t_l9r_go_relaxed.owl	activation of lipid transport across blood brain barrier|upregulation of lipid transport across blood brain barrier|up regulation of lipid transport across blood brain barrier|positive regulation of lipid transport across blood brain barrier|up-regulation of lipid transport across blood brain barrier							sjp	2014-05-09T09:30:16Z					biological_process											owl:Class	
GO:0102859	biolink:NamedThing	1-18:1-2-18:2-phosphatidylcholine desaturase activity (SN2-18:3 forming)	Catalysis of the reaction: 1-18:1-2-18:2-phosphatidylcholine + O2 + a reduced electron acceptor = 1-18:1-2-18:3-phosphatidylcholine + 2 H2O + an oxidized electron acceptor.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-8326|RHEA:46404|EC:1.14.19.25									molecular_function											owl:Class	
GO:0071337	biolink:NamedThing	negative regulation of hair follicle cell proliferation	Any process that stops, prevents or reduces the rate or extent of hair follicle cell proliferation.	tmpzr1t_l9r_go_relaxed.owl	inhibition of hair follicle cell proliferation|downregulation of hair follicle cell proliferation|down-regulation of hair follicle cell proliferation|down regulation of hair follicle cell proliferation							mah	2009-12-11T10:59:20Z					biological_process											owl:Class	
GO:0042898	biolink:NamedThing	fosmidomycin transmembrane transporter activity	Enables the transfer of fosmidomycin, a phosphonic acid derivative with potent activity against Gram-negative organisms, from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	fosmidomycin transporter activity													molecular_function											owl:Class	
GO:0048816	biolink:NamedThing	ocellus morphogenesis	The process in which the anatomical structures of the ocellus are generated and organized. The ocellus is a simple visual organ of insects.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0090596	biolink:NamedThing	sensory organ morphogenesis	Morphogenesis of a sensory organ. A sensory organ is defined as a tissue or set of tissues that work together to receive and transmit signals from external or internal stimuli. Morphogenesis is the process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.	tmpzr1t_l9r_go_relaxed.owl								tb	2014-08-22T13:23:20Z					biological_process											owl:Class	
GO:0043599	biolink:NamedThing	nuclear DNA replication factor C complex	A nuclear complex of five polypeptides that loads the DNA polymerase processivity factor proliferating cell nuclear antigen (PCNA) onto DNA, thereby permitting processive DNA synthesis catalyzed by DNA polymerase delta or epsilon. In Saccharomyces and several other species, the subunits are known as Rfc1p-Rfc5p, although subunit names do not necessarily correspond between different species.	tmpzr1t_l9r_go_relaxed.owl	nuclear RFC													cellular_component											owl:Class	
GO:1902249	biolink:NamedThing	IMP binding	Binding to IMP, inosine monophosphate.	tmpzr1t_l9r_go_relaxed.owl								mah	2013-06-20T16:20:35Z					molecular_function											owl:Class	
GO:0048339	biolink:NamedThing	paraxial mesoderm development	The process whose specific outcome is the progression of the paraxial mesoderm over time, from its formation to the mature structure. The paraxial mesoderm is the mesoderm located bilaterally adjacent to the notochord and neural tube.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1903838	biolink:NamedThing	negative regulation of mRNA 3'-UTR binding	Any process that stops, prevents or reduces the frequency, rate or extent of mRNA 3'-UTR binding.	tmpzr1t_l9r_go_relaxed.owl	inhibition of mRNA 3'-UTR binding|down-regulation of mRNA 3' UTR binding|down regulation of mRNA 3' UTR binding|downregulation of mRNA 3'-UTR binding|negative regulation of mRNA 3' UTR binding|down regulation of mRNA 3'-UTR binding|down-regulation of mRNA 3'-UTR binding|inhibition of mRNA 3' UTR binding|downregulation of mRNA 3' UTR binding							als	2015-01-22T11:54:08Z					biological_process											owl:Class	
GO:0019187	biolink:NamedThing	beta-1,4-mannosyltransferase activity	Catalysis of the transfer of a mannose residue to an oligosaccharide, forming a beta-(1->4) linkage.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0000030	biolink:NamedThing	mannosyltransferase activity	Catalysis of the transfer of a mannosyl group to an acceptor molecule, typically another carbohydrate or a lipid.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-162797|Reactome:R-HSA-446198|Reactome:R-HSA-162830|Reactome:R-HSA-4720497									molecular_function											owl:Class	
GO:0009889	biolink:NamedThing	regulation of biosynthetic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances.	tmpzr1t_l9r_go_relaxed.owl	regulation of synthesis|regulation of biosynthesis|regulation of formation|regulation of anabolism													biological_process											owl:Class	
GO:0090340	biolink:NamedThing	positive regulation of secretion of lysosomal enzymes	Any process that increases the rate, frequency or extent of secretion of lysosomal enzymes, the controlled release of lysosomal enzymes by a cell.	tmpzr1t_l9r_go_relaxed.owl								tb	2010-06-01T03:35:57Z					biological_process											owl:Class	
GO:1900658	biolink:NamedThing	regulation of emericellamide biosynthetic process	Any process that modulates the frequency, rate or extent of emericellamide biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of emericellamide formation|regulation of emericellamide biosynthesis|regulation of emericellamide synthesis|regulation of emericellamide anabolism							di	2012-05-22T04:10:19Z					biological_process											owl:Class	
GO:0032620	biolink:NamedThing	interleukin-17 production	The appearance of any member of the interleukin-17 family of cytokines due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	tmpzr1t_l9r_go_relaxed.owl	Cytotoxic T-lymphocyte-associated antigen 8 production|interleukin-17 secretion|interleukin-17 biosynthetic process|CTLA-8 production|IL-17 production											GO:0042235|GO:0072615		biological_process											owl:Class	
GO:0010067	biolink:NamedThing	procambium histogenesis	The formation of the primary meristem or meristematic tissue that gives rise to the primary vascular tissue.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0010065	biolink:NamedThing	primary meristem tissue development	The process whose specific outcome is the progression of the primary meristem over time, from formation to the mature structure, as it occurs during plant embryogenesis. The primary meristem tissue is the protoderm, ground meristem and procambium.	tmpzr1t_l9r_go_relaxed.owl	primary meristem histogenesis													biological_process											owl:Class	
GO:0102344	biolink:NamedThing	3-hydroxy-behenoyl-CoA dehydratase activity	Catalysis of the reaction: (R)-3-hydroxybehenoyl-CoA <=> trans-2-docosenoyl-CoA + H2O.	tmpzr1t_l9r_go_relaxed.owl					EC:4.2.1.134|MetaCyc:RXN-13303									molecular_function											owl:Class	
GO:1902818	biolink:NamedThing	ethyl acetate metabolic process	The chemical reactions and pathways involving ethyl acetate.	tmpzr1t_l9r_go_relaxed.owl	ethyl acetate metabolism|ethyl ethanoate metabolic process							tt	2014-03-30T20:26:47Z					biological_process											owl:Class	
GO:1900619	biolink:NamedThing	acetate ester metabolic process	The chemical reactions and pathways involving an acetate ester, any carboxylic ester where the carboxylic acid component is acetic acid.	tmpzr1t_l9r_go_relaxed.owl	acetate ester metabolism|acetyl ester metabolic process|acetyl ester metabolism							bf	2012-05-16T12:29:51Z					biological_process											owl:Class	
GO:1990159	biolink:NamedThing	DnaB-DnaC-DnaT-PriA-PriC complex	A protein-DNA complex consisting of the helicase loading complex DnaB-DnaC, replication restart proteins DnaT, PriA and PriC, and associated DNA. Involved in the restart of DNA replication after a stalled replication fork has been repaired.	tmpzr1t_l9r_go_relaxed.owl	phi-X174-type preprimosome|DnaB-DnaC-DnaT-PriA-PriC preprimosome							bhm	2013-08-02T11:58:16Z					cellular_component											owl:Class	
GO:1990099	biolink:NamedThing	pre-primosome complex	Any of the protein-DNA complexes that contain a DNA helicase and associated protein(s) at the origin of replication, and build up to assembling the core primosome. The associated protein(s) chaperone the helicase to the DNA, and assembly of the pre-primosome is essential for the initiation or restart of replication. Pre-primosome complexes lack a primase component.	tmpzr1t_l9r_go_relaxed.owl	pre-replication complex|prereplication complex|preprimosome|pre-primosome|pre-priming complex|preprimosome complex							bhm	2013-05-14T10:53:42Z					cellular_component											owl:Class	
GO:0061762	biolink:NamedThing	CAMKK-AMPK signaling cascade	A series of molecular signals in which calmodulin-dependent protein kinase activity enabled by a CAMKK directly activates an AMPK. The cascade begins with calmodulin binding calcium which in turn binds CAMKK enabling its calmodulin-dependent protein kinase activity. The cascade ends with AMP-activated protein kinase activity.	tmpzr1t_l9r_go_relaxed.owl	stress-activated AMP-activated protein kinase signaling cascade							dph	2016-04-14T12:59:31Z					biological_process											owl:Class	
GO:0099004	biolink:NamedThing	calmodulin dependent kinase signaling pathway	Any signal transduction pathway involving calmodulin dependent kinase activity.	tmpzr1t_l9r_go_relaxed.owl	CAMK signaling pathway													biological_process											owl:Class	
GO:0072690	biolink:NamedThing	single-celled organism vegetative growth phase	A phase of population growth during which single celled organisms reproduce by budding, fission, or other asexual methods.	tmpzr1t_l9r_go_relaxed.owl	vegetative growth of a single-celled organism|stationary phase	https://github.com/geneontology/go-ontology/issues/18275				Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase. To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).		mah	2011-08-19T12:05:19Z			GO:0062178		biological_process											owl:Class	
GO:0044848	biolink:NamedThing	biological phase	A distinct period or stage in a biological process or cycle.	tmpzr1t_l9r_go_relaxed.owl						Note that phases are is_a disjoint from other biological processes. happens_during relationships can operate between phases and other biological processes e.g. DNA replication happens_during S phase.		jl	2014-07-16T13:12:40Z					biological_process											owl:Class	
GO:1900263	biolink:NamedThing	negative regulation of DNA-directed DNA polymerase activity	Any process that stops, prevents or reduces the frequency, rate or extent of DNA-directed DNA polymerase activity.	tmpzr1t_l9r_go_relaxed.owl	down regulation of duplicase|negative regulation of kappa DNA polymerase activity|down-regulation of eta DNA polymerase activity|down-regulation of DNA-directed DNA polymerase activity|inhibition of iota DNA polymerase activity|downregulation of Tca DNA polymerase|down regulation of lambda DNA polymerase activity|inhibition of alpha DNA polymerase activity|inhibition of DNA polymerase I|down-regulation of DNA polymerase gamma|down-regulation of nu DNA polymerase activity|down regulation of DNA polymerase III|down-regulation of DNA polymerase alpha|downregulation of theta DNA polymerase activity|negative regulation of alpha DNA polymerase activity|down-regulation of DNA polymerase III|down regulation of epsilon DNA polymerase activity|down-regulation of mu DNA polymerase activity|down regulation of DNA replicase activity|inhibition of DNA polymerase III|downregulation of mu DNA polymerase activity|negative regulation of deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (DNA-directed) activity|down regulation of DNA polymerase gamma|down-regulation of DNA replicase activity|inhibition of sigma DNA polymerase activity|inhibition of DNA polymerase II|negative regulation of Taq DNA polymerase|down regulation of DNA nucleotidyltransferase (DNA-directed) activity|negative regulation of deoxyribonucleic acid duplicase activity|inhibition of DNA polymerase alpha|inhibition of duplicase|downregulation of alpha DNA polymerase activity|downregulation of sigma DNA polymerase activity|down regulation of eta DNA polymerase activity|down regulation of gamma DNA-directed DNA polymerase activity|inhibition of DNA polymerase V activity|negative regulation of zeta DNA polymerase activity|inhibition of DNA-directed DNA polymerase activity|down-regulation of Taq Pol I|down-regulation of duplicase|inhibition of Tca DNA polymerase|down regulation of deoxyribonucleic acid duplicase activity|down-regulation of lambda DNA polymerase activity|inhibition of Klenow fragment|down regulation of sigma DNA polymerase activity|down regulation of sequenase|negative regulation of beta DNA polymerase activity|downregulation of nu DNA polymerase activity|inhibition of zeta DNA polymerase activity|downregulation of iota DNA polymerase activity|inhibition of deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (DNA-directed) activity|inhibition of DNA polymerase beta|inhibition of delta DNA polymerase activity|down-regulation of deoxyribonucleic acid duplicase activity|down regulation of Tca DNA polymerase|inhibition of nu DNA polymerase activity|downregulation of DNA polymerase V activity|inhibition of theta DNA polymerase activity|down-regulation of sequenase|down-regulation of kappa DNA polymerase activity|inhibition of DNA replicase activity|negative regulation of DNA nucleotidyltransferase (DNA-directed) activity|negative regulation of gamma DNA-directed DNA polymerase activity|downregulation of epsilon DNA polymerase activity|negative regulation of deoxyribonucleic duplicase activity|down-regulation of Klenow fragment|down regulation of Taq DNA polymerase|negative regulation of nu DNA polymerase activity|down-regulation of deoxyribonucleic duplicase activity|negative regulation of sigma DNA polymerase activity|negative regulation of lambda DNA polymerase activity|negative regulation of DNA-dependent DNA polymerase activity|downregulation of deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (DNA-directed) activity|negative regulation of deoxyribonucleic polymerase I|inhibition of Taq Pol I|negative regulation of DNA polymerase gamma|down-regulation of Taq DNA polymerase|negative regulation of mu DNA polymerase activity|downregulation of DNA polymerase II|inhibition of epsilon DNA polymerase activity|down regulation of mu DNA polymerase activity|downregulation of DNA polymerase beta|inhibition of beta DNA polymerase activity|down regulation of DNA polymerase II|down-regulation of DNA duplicase activity|inhibition of DNA duplicase activity|down regulation of Klenow fragment|downregulation of DNA polymerase gamma|downregulation of beta DNA polymerase activity|negative regulation of sequenase|down-regulation of delta DNA polymerase activity|down regulation of zeta DNA polymerase activity|negative regulation of iota DNA polymerase activity|inhibition of lambda DNA polymerase activity|negative regulation of DNA polymerase II|inhibition of mu DNA polymerase activity|downregulation of lambda DNA polymerase activity|downregulation of DNA-directed DNA polymerase activity|inhibition of eta DNA polymerase activity|downregulation of zeta DNA polymerase activity|down regulation of beta DNA polymerase activity|down regulation of Taq Pol I|down-regulation of DNA polymerase V activity|negative regulation of DNA replicase activity|downregulation of DNA nucleotidyltransferase (DNA-directed) activity|downregulation of Taq DNA polymerase|down regulation of DNA polymerase beta|down-regulation of epsilon DNA polymerase activity|down regulation of nu DNA polymerase activity|down-regulation of DNA polymerase beta|negative regulation of DNA polymerase I|negative regulation of delta DNA polymerase activity|negative regulation of duplicase|inhibition of gamma DNA-directed DNA polymerase activity|inhibition of DNA-dependent DNA polymerase activity|downregulation of DNA replicase activity|down-regulation of gamma DNA-directed DNA polymerase activity|down-regulation of beta DNA polymerase activity|inhibition of DNA nucleotidyltransferase (DNA-directed) activity|negative regulation of DNA polymerase V activity|negative regulation of Taq Pol I|down regulation of DNA-dependent DNA polymerase activity|down regulation of DNA-directed DNA polymerase activity|downregulation of Klenow fragment|down regulation of DNA polymerase I|downregulation of delta DNA polymerase activity|down-regulation of deoxyribonucleic polymerase I|downregulation of sequenase|inhibition of kappa DNA polymerase activity|negative regulation of DNA polymerase III|down-regulation of iota DNA polymerase activity|down regulation of theta DNA polymerase activity|down regulation of DNA polymerase alpha|negative regulation of eta DNA polymerase activity|downregulation of DNA-dependent DNA polymerase activity|down regulation of DNA duplicase activity|downregulation of deoxyribonucleic acid duplicase activity|down regulation of iota DNA polymerase activity|down-regulation of DNA-dependent DNA polymerase activity|downregulation of duplicase|negative regulation of theta DNA polymerase activity|inhibition of sequenase|inhibition of deoxyribonucleic acid duplicase activity|downregulation of deoxyribonucleic polymerase I|down-regulation of sigma DNA polymerase activity|down-regulation of alpha DNA polymerase activity|negative regulation of DNA polymerase alpha|negative regulation of epsilon DNA polymerase activity|down-regulation of DNA nucleotidyltransferase (DNA-directed) activity|down-regulation of DNA polymerase I|down-regulation of theta DNA polymerase activity|downregulation of DNA polymerase III|negative regulation of DNA polymerase beta|down-regulation of Tca DNA polymerase|inhibition of deoxyribonucleic duplicase activity|inhibition of DNA polymerase gamma|downregulation of kappa DNA polymerase activity|downregulation of deoxyribonucleic duplicase activity|downregulation of Taq Pol I|negative regulation of Tca DNA polymerase|downregulation of eta DNA polymerase activity|inhibition of deoxyribonucleic polymerase I|down regulation of DNA polymerase V activity|down regulation of delta DNA polymerase activity|down regulation of deoxyribonucleic duplicase activity|negative regulation of Klenow fragment|downregulation of DNA polymerase alpha|down-regulation of DNA polymerase II|inhibition of Taq DNA polymerase|downregulation of gamma DNA-directed DNA polymerase activity|down regulation of deoxyribonucleic polymerase I|downregulation of DNA polymerase I|down-regulation of deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (DNA-directed) activity|down-regulation of zeta DNA polymerase activity|negative regulation of DNA duplicase activity|down regulation of deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (DNA-directed) activity|downregulation of DNA duplicase activity|down regulation of alpha DNA polymerase activity|down regulation of kappa DNA polymerase activity							tb	2012-04-03T11:07:18Z					biological_process											owl:Class	
GO:1900262	biolink:NamedThing	regulation of DNA-directed DNA polymerase activity	Any process that modulates the frequency, rate or extent of DNA-directed DNA polymerase activity.	tmpzr1t_l9r_go_relaxed.owl	regulation of iota DNA polymerase activity|regulation of deoxyribonucleic acid duplicase activity|regulation of DNA duplicase activity|regulation of gamma DNA-directed DNA polymerase activity|regulation of DNA polymerase I|regulation of beta DNA polymerase activity|regulation of lambda DNA polymerase activity|regulation of alpha DNA polymerase activity|regulation of eta DNA polymerase activity|regulation of DNA-dependent DNA polymerase activity|regulation of DNA polymerase beta|regulation of DNA polymerase II|regulation of Tca DNA polymerase|regulation of sequenase|regulation of zeta DNA polymerase activity|regulation of Klenow fragment|regulation of delta DNA polymerase activity|regulation of duplicase|regulation of DNA replicase activity|regulation of DNA polymerase III|regulation of mu DNA polymerase activity|regulation of theta DNA polymerase activity|regulation of kappa DNA polymerase activity|regulation of DNA polymerase gamma|regulation of Taq DNA polymerase|regulation of Taq Pol I|regulation of deoxyribonucleic duplicase activity|regulation of epsilon DNA polymerase activity|regulation of deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (DNA-directed) activity|regulation of DNA nucleotidyltransferase (DNA-directed) activity|regulation of nu DNA polymerase activity|regulation of deoxyribonucleic polymerase I|regulation of sigma DNA polymerase activity|regulation of DNA polymerase alpha|regulation of DNA polymerase V activity							tb	2012-04-03T11:07:08Z					biological_process											owl:Class	
GO:0036463	biolink:NamedThing	TRAIL receptor activity	Combining with the ligand TRAIL (tumor necrosis factor-related apoptosis-inducing ligand) and transmitting the signal from one side of the plasma membrane to the other to initiate apoptotic cell death.	tmpzr1t_l9r_go_relaxed.owl	tumor necrosis factor-related apoptosis-inducing ligand receptor							bf	2014-06-11T09:20:30Z					molecular_function											owl:Class	
GO:0005035	biolink:NamedThing	death receptor activity	Combining with an extracellular messenger (called a death ligand), and transmitting the signal from one side of the plasma membrane to the other to initiate apoptotic or necrotic cell death.	tmpzr1t_l9r_go_relaxed.owl	apoptosis-activating receptor activity													molecular_function											owl:Class	
GO:0032243	biolink:NamedThing	negative regulation of nucleoside transport	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a nucleoside into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of nucleoside transport|downregulation of nucleoside transport|down regulation of nucleoside transport|inhibition of nucleoside transport													biological_process											owl:Class	
GO:0032240	biolink:NamedThing	negative regulation of nucleobase-containing compound transport	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport|down-regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport|down regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport|downregulation of nucleobase, nucleoside, nucleotide and nucleic acid transport|inhibition of nucleobase, nucleoside, nucleotide and nucleic acid transport													biological_process											owl:Class	
GO:0030418	biolink:NamedThing	nicotianamine biosynthetic process	The chemical reactions and pathways resulting in the formation of nicotianamine, 2(S),3'2(S),3''(S)-N-(N-(3-amino-3-carboxypropyl)-3-amino-3-carboxypropyl)-azetidine-2-carboxylic acid.	tmpzr1t_l9r_go_relaxed.owl	nicotianamine synthesis|nicotianamine biosynthesis|nicotianamine formation|nicotianamine anabolism													biological_process											owl:Class	
GO:1990584	biolink:NamedThing	cardiac Troponin complex	A complex of accessory proteins (cardiac troponin T, cardiac troponin I and cardiac troponin C) found associated with actin in cardiac muscle thin filaments; involved in calcium regulation important for muscle contraction.	tmpzr1t_l9r_go_relaxed.owl	cTnC:cTnI:cTnT							ame	2014-12-12T16:51:41Z					cellular_component											owl:Class	
GO:0005861	biolink:NamedThing	troponin complex	A complex of accessory proteins (typically troponin T, troponin I and troponin C) found associated with actin in muscle thin filaments; involved in calcium regulation of muscle contraction.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0080035	biolink:NamedThing	2-hydroxy-but-3-enyl glucosinolate biosynthetic process	The chemical reactions and pathways resulting in the formation of progoitrin, a 2-hydroxy-but-3-enyl glucosinolate. Glucosinolates are substituted thioglucosides found in rapeseed products and related cruciferae, and progoitrin has been implicated in causing goiters in mammals and bitter taste in cruciferous vegetables.	tmpzr1t_l9r_go_relaxed.owl	2-hydroxy-but-3-enyl glucosinolate anabolism|progoitrin synthesis|2-hydroxy-but-3-enyl glucosinolate biosynthesis|progoitrin biosynthesis|progoitrin biosynthetic process|2-hydroxy-but-3-enyl glucosinolate synthesis|2-hydroxy-but-3-enyl glucosinolate formation													biological_process											owl:Class	
GO:1903022	biolink:NamedThing	positive regulation of phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands	Any process that activates or increases the frequency, rate or extent of phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands.	tmpzr1t_l9r_go_relaxed.owl	activation of phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands|upregulation of phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands|up regulation of phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands|up-regulation of phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands							tb	2014-05-14T23:44:47Z					biological_process											owl:Class	
GO:0031459	biolink:NamedThing	ABC-type glycine betaine transporter activity	Catalysis of the reaction: ATP + H2O + glycine betaine(out) = ADP + phosphate + glycine betaine(in).	tmpzr1t_l9r_go_relaxed.owl	glycine betaine ABC transporter|N-trimethylglycine-transporting ATPase activity|glycine betaine-transporting ATPase activity|ATP-dependent glycine betaine transporter activity|ATPase-coupled glycine betaine transporter activity				RHEA:32783									molecular_function											owl:Class	
GO:0015418	biolink:NamedThing	ABC-type quaternary ammonium compound transporting activity	Catalysis of the reaction: ATP + H2O + quaternary ammonium(out) = ADP + H(+) + phosphate + quaternary ammonium(in).	tmpzr1t_l9r_go_relaxed.owl	quarternary amine transporter activity|ATP-dependent quaternary-ammonium compound transmembrane transporting activity|glycine betaine/proline porter activity|quaternary-ammonium-compound ABC transporter|quaternary amine uptake transporter activity|quaternary-ammonium-compound-transporting ATPase activity|quaternary-amine-transporting ATPase activity|ATPase-coupled quaternary ammonium compound transmembrane transporting activity				MetaCyc:RXN-8638|RHEA:11036|EC:7.6.2.9|MetaCyc:3.6.3.32-RXN							GO:0102908		molecular_function											owl:Class	
GO:0035906	biolink:NamedThing	descending aorta development	The progression of the descending aorta over time, from its initial formation to the mature structure. The descending aorta is the portion of the aorta in a two-pass circulatory system from the arch of aorta to the point where it divides into the common iliac arteries. In a two-pass circulatory system blood passes twice through the heart to supply the body once.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-06-24T11:05:22Z					biological_process											owl:Class	
GO:0043214	biolink:NamedThing	ABC-type bacteriocin transporter activity	Enables the transfer of a bacteriocin from one side of a membrane to the other according to the reaction: ATP + H2O = ADP + phosphate.	tmpzr1t_l9r_go_relaxed.owl	bacteriocin ABC transporter|ATPase-coupled bacteriocin transmembrane transporter activity|ABC-type bacteriocin transmembrane transporter activity													molecular_function											owl:Class	
GO:0008559	biolink:NamedThing	ABC-type xenobiotic transporter activity	Catalysis of the reaction: ATP + H2O + xenobiotic(in) = ADP + phosphate + xenobiotic(out).	tmpzr1t_l9r_go_relaxed.owl	ATP-dependent xenobiotic transmembrane transporter activity|xenobiotic ABC transporter|multidrug-resistance protein|MDR protein|ATP phosphohydrolase (xenobiotic-exporting)|ATPase-coupled xenobiotic transmembrane transporter activity|PDR protein|xenobiotic transmembrane transporting ATPase activity|multidrug resistance exporter|P-glycoprotein|pleiotropic-drug-resistance protein				MetaCyc:3.6.3.44-RXN|EC:7.6.2.2							GO:0005226|GO:0008560		molecular_function											owl:Class	
GO:0072721	biolink:NamedThing	cellular response to dithiothreitol	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dithiothreitol stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to 1,4-dithiothreitol|cellular response to DTT							mah	2012-05-09T11:09:08Z					biological_process											owl:Class	
GO:0061433	biolink:NamedThing	cellular response to caloric restriction	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a of caloric restriction, insufficient food energy intake.	tmpzr1t_l9r_go_relaxed.owl								dph	2012-02-09T09:03:15Z					biological_process											owl:Class	
GO:0061771	biolink:NamedThing	response to caloric restriction	A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a caloric restriction, insufficient food energy intake.	tmpzr1t_l9r_go_relaxed.owl								dph	2016-07-09T09:40:32Z					biological_process											owl:Class	
GO:0002637	biolink:NamedThing	regulation of immunoglobulin production	Any process that modulates the frequency, rate, or extent of immunoglobulin production.	tmpzr1t_l9r_go_relaxed.owl	regulation of immunoglobulin secretion|regulation of antibody production|regulation of immunoglobulin biosynthetic process											GO:0002640|GO:0051023		biological_process											owl:Class	
GO:0098610	biolink:NamedThing	adhesion between unicellular organisms	The attachment of two unicellular organisms to each other.	tmpzr1t_l9r_go_relaxed.owl	multi-organismal cell-cell adhesion|adhesion between unicellular organisms via cell-wall interaction	https://github.com/geneontology/go-ontology/issues/18814										GO:0098741		biological_process											owl:Class	
GO:0030861	biolink:NamedThing	negative regulation of polarized epithelial cell differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of polarized epithelial cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	inhibition of polarized epithelial cell differentiation|down-regulation of polarized epithelial cell differentiation|downregulation of polarized epithelial cell differentiation|down regulation of polarized epithelial cell differentiation													biological_process											owl:Class	
GO:0046475	biolink:NamedThing	glycerophospholipid catabolic process	The chemical reactions and pathways resulting in the breakdown of glycerophospholipids, any derivative of glycerophosphate that contains at least one O-acyl, O-alkyl, or O-alkenyl group attached to the glycerol residue.	tmpzr1t_l9r_go_relaxed.owl	glycerophospholipid catabolism|phosphoglyceride catabolism|phosphoglyceride catabolic process|glycerophospholipid degradation|glycerophospholipid breakdown													biological_process											owl:Class	
GO:0046503	biolink:NamedThing	glycerolipid catabolic process	The chemical reactions and pathways resulting in the breakdown of glycerolipids, any lipid with a glycerol backbone.	tmpzr1t_l9r_go_relaxed.owl	glycerolipid breakdown|glycerolipid degradation|glycerolipid catabolism													biological_process											owl:Class	
GO:0110111	biolink:NamedThing	negative regulation of animal organ morphogenesis	Any process that stops, prevents, or reduces the frequency, rate or extent of animal organ morphogenesis.	tmpzr1t_l9r_go_relaxed.owl								kmv	2018-07-05T14:25:21Z					biological_process											owl:Class	
GO:0060190	biolink:NamedThing	negative regulation of protein desumoylation	Any process that decreases the frequency, rate or extent of protein desumoylation. Protein desumoylation is the process in which a SUMO protein (small ubiquitin-related modifier) is cleaved from its target protein.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1903321	biolink:NamedThing	negative regulation of protein modification by small protein conjugation or removal	Any process that stops, prevents or reduces the frequency, rate or extent of protein modification by small protein conjugation or removal.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of protein modification by small protein conjugation or removal|inhibition of protein modification by small protein conjugation or removal|downregulation of protein modification by small protein conjugation or removal|down regulation of protein modification by small protein conjugation or removal							vw	2014-08-18T13:01:08Z					biological_process											owl:Class	
GO:0010675	biolink:NamedThing	regulation of cellular carbohydrate metabolic process	Any process that modulates the rate, extent or frequency of the chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y, as carried out by individual cells.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1903329	biolink:NamedThing	regulation of iron-sulfur cluster assembly	Any process that modulates the frequency, rate or extent of iron-sulfur cluster assembly.	tmpzr1t_l9r_go_relaxed.owl								vw	2014-08-18T13:12:41Z					biological_process											owl:Class	
GO:0071793	biolink:NamedThing	bacillithiol biosynthetic process	The chemical reactions and pathways resulting in the formation of bacillithiol, the alpha-anomeric glycoside of L-cysteinyl-D-glucosamine with L-malic acid. Bacillithiol, produced widely in the Firmicutes and sporadically in other bacterial lineages, is a low-molecular-weight thiol analogous to mycothiol in the Actinomycetes and glutathione in many species.	tmpzr1t_l9r_go_relaxed.owl	bacillithiol biosynthesis|bacillithiol anabolism|bacillithiol synthesis|bacillithiol formation							mah	2010-09-02T11:16:04Z					biological_process											owl:Class	
GO:1905100	biolink:NamedThing	regulation of apoptosome assembly	Any process that modulates the frequency, rate or extent of apoptosome assembly.	tmpzr1t_l9r_go_relaxed.owl	regulation of apoptosome formation							bc	2016-04-04T08:57:42Z					biological_process											owl:Class	
GO:0090325	biolink:NamedThing	regulation of locomotion involved in locomotory behavior	Any process that modulates the frequency, rate, or extent of the self-propelled movement of a cell or organism from one location to another in a behavioral context; the aspect of locomotory behavior having to do with movement.	tmpzr1t_l9r_go_relaxed.owl								tb	2010-05-14T10:24:29Z					biological_process											owl:Class	
GO:0048222	biolink:NamedThing	glycoprotein network	An extracellular matrix part that consists of cross-linked glycoproteins.	tmpzr1t_l9r_go_relaxed.owl	extensin				Wikipedia:Extensin									cellular_component											owl:Class	
GO:0062174	biolink:NamedThing	brexanolone biosynthetic process	The chemical reactions and pathways resulting in the formation of brexanolone.	tmpzr1t_l9r_go_relaxed.owl	allotetrahydroprogesterone anabolism|allotetrahydroprogesterone synthesis|allotetrahydroprogesterone biosynthetic process|allopregnanolone synthesis|allopregnanolone biosynthesis|allopregnanolone anabolism|allopregnanolone biosynthetic process|allotetrahydroprogesterone biosynthesis|brexanolone synthesis|brexanolone anabolism|brexanolone biosynthesis							dph	2019-11-18T19:48:14Z					biological_process											owl:Class	
GO:1900871	biolink:NamedThing	chloroplast mRNA modification	The covalent alteration within the chloroplast of one or more nucleotides within an mRNA to produce an mRNA molecule with a sequence that differs from that coded genetically.	tmpzr1t_l9r_go_relaxed.owl	mRNA editing in chloroplast|chloroplast mRNA editing							dhl	2012-06-12T06:13:58Z					biological_process											owl:Class	
GO:0016556	biolink:NamedThing	mRNA modification	The covalent alteration of one or more nucleotides within an mRNA molecule to produce an mRNA molecule with a sequence that differs from that coded genetically.	tmpzr1t_l9r_go_relaxed.owl	mRNA editing					The term 'RNA editing' (GO:0016547) was merged into 'RNA modification' (GO:0009451) on the basis of statements in the preface of Modification and Editing of RNA (ISBN:1555811337) that there is no clear distinction between modification and editing. Parallel changes were made for substrate (e.g. tRNA, rRNA, etc.) specific child terms of 'RNA editing'.						GO:0006381		biological_process											owl:Class	
GO:2000266	biolink:NamedThing	regulation of blood coagulation, intrinsic pathway	Any process that modulates the frequency, rate or extent of blood coagulation, intrinsic pathway.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-11-23T11:45:40Z					biological_process											owl:Class	
GO:2000781	biolink:NamedThing	positive regulation of double-strand break repair	Any process that activates or increases the frequency, rate or extent of double-strand break repair.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-06-23T09:28:13Z					biological_process											owl:Class	
GO:0008343	biolink:NamedThing	adult feeding behavior	Feeding behavior in a fully developed and mature organism.	tmpzr1t_l9r_go_relaxed.owl	adult feeding behaviour					See also the biological process term 'feeding behavior ; GO:0007631'.								biological_process											owl:Class	
GO:0007631	biolink:NamedThing	feeding behavior	Behavior associated with the intake of food.	tmpzr1t_l9r_go_relaxed.owl	hematophagy|feeding from vascular tissue of another organism|feeding from xylem of other organism|taking of blood meal|behavioural response to food|feeding from tissue of other organism|feeding on plant sap|injection of substance into other organism during feeding on blood of other organism|feeding from plant phloem|eating|behavioral response to food|feeding behaviour|feeding on or from other organism|feeding from phloem of other organism|feeding on blood of other organism	https://github.com/geneontology/go-ontology/issues/18547			Wikipedia:List_of_feeding_behaviours	See also the biological process term 'behavior ; GO:0007610'.		jl	2011-10-27T03:53:33Z			GO:0044367|GO:0044368|GO:0044369|GO:0044372|GO:0044366|GO:0044371|GO:0044370		biological_process											owl:Class	
GO:0009873	biolink:NamedThing	ethylene-activated signaling pathway	A series of molecular signals generated by the reception of ethylene (ethene, C2H4) by a receptor and ending with modulation of a cellular process, e.g. transcription.	tmpzr1t_l9r_go_relaxed.owl	ethylene mediated signaling pathway|ethylene signal transduction|ethylene signaling pathway|ethene mediated signalling pathway|ethylene mediated signalling pathway|ethene mediated signaling pathway													biological_process											owl:Class	
GO:0009755	biolink:NamedThing	hormone-mediated signaling pathway	A series of molecular signals mediated by the detection of a hormone.	tmpzr1t_l9r_go_relaxed.owl	hormone mediated signalling													biological_process											owl:Class	
GO:0016774	biolink:NamedThing	phosphotransferase activity, carboxyl group as acceptor	Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to a carboxyl group (acceptor).	tmpzr1t_l9r_go_relaxed.owl					EC:2.7.2.-									molecular_function											owl:Class	
GO:0055069	biolink:NamedThing	zinc ion homeostasis	Any process involved in the maintenance of an internal steady state of zinc ions within an organism or cell.	tmpzr1t_l9r_go_relaxed.owl	zinc homeostasis													biological_process											owl:Class	
GO:0055076	biolink:NamedThing	transition metal ion homeostasis	Any process involved in the maintenance of an internal steady state of transition metal ions within an organism or cell. A transition metal is an element whose atom has an incomplete d-subshell of extranuclear electrons, or which gives rise to a cation or cations with an incomplete d-subshell. Transition metals often have more than one valency state. Biologically relevant transition metals include vanadium, manganese, iron, copper, cobalt, nickel, molybdenum and silver.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0031243	biolink:NamedThing	intrinsic component of external side of cell outer membrane	The component of the cell outer membrane consisting of the gene products and protein complexes that penetrate the external side of the cell outer membrane only, either directly or via some covalently attached hydrophobic anchor.	tmpzr1t_l9r_go_relaxed.owl	intrinsic to external side of cell outer membrane|intrinsic to external leaflet of cell outer membrane|intrinsic to external side of outer membrane													cellular_component											owl:Class	
GO:0048240	biolink:NamedThing	sperm capacitation	A process required for sperm to reach fertilization competence. Sperm undergo an incompletely understood series of morphological and molecular maturational processes, termed capacitation, involving, among other processes, protein tyrosine phosphorylation and increased intracellular calcium.	tmpzr1t_l9r_go_relaxed.owl	sperm activation					Avian spermatozoa do not require a period of capacitation, since they are competent to fertilize the egg without a prolonged sojourn in the oviduct or in a capacitation medium in vitro. Therefore, sperm capacitation can only be applied to Aves to refer to gene products involved in processes that occur prior to sperm being deposited from the avian male. The term cannot apply to processes occurring in the avian female reproductive tract.								biological_process											owl:Class	
GO:0062087	biolink:NamedThing	positive regulation of vein smooth muscle contraction	Any process that increases the frequency, rate or extent of vein smooth muscle contraction.	tmpzr1t_l9r_go_relaxed.owl								dph	2018-11-02T15:20:47Z					biological_process											owl:Class	
GO:0035713	biolink:NamedThing	response to nitrogen dioxide	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrogen dioxide (NO2) stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to NO2							bf	2011-03-02T03:14:51Z					biological_process											owl:Class	
GO:1901124	biolink:NamedThing	bacitracin A biosynthetic process	The chemical reactions and pathways resulting in the formation of bacitracin A.	tmpzr1t_l9r_go_relaxed.owl	bacitracin A formation|bacitracin A anabolism|bacitracin A biosynthesis|bacitracin A synthesis							yaf	2012-07-11T03:16:27Z					biological_process											owl:Class	
GO:0016775	biolink:NamedThing	phosphotransferase activity, nitrogenous group as acceptor	Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to a nitrogenous group (acceptor).	tmpzr1t_l9r_go_relaxed.owl					EC:2.7.3.-									molecular_function											owl:Class	
GO:0000901	biolink:NamedThing	translation repressor activity, non-nucleic acid binding	Antagonizes the ribosome-mediated translation of mRNA into a polypeptide but does not bind directly to nucleic acid.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0030371	biolink:NamedThing	translation repressor activity	Antagonizes ribosome-mediated translation of mRNA into a polypeptide.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1905894	biolink:NamedThing	regulation of cellular response to tunicamycin	Any process that modulates the frequency, rate or extent of cellular response to tunicamycin.	tmpzr1t_l9r_go_relaxed.owl								bc	2017-02-01T11:36:34Z					biological_process											owl:Class	
GO:0030937	biolink:NamedThing	collagen type XVII trimer	A collagen homotrimer of alpha1(XVII) chains; type XVII collagen triple helices span the plasma membrane and associate with hemidesmosomes and the basal lamina where they bind laminin.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0030936	biolink:NamedThing	transmembrane collagen trimer	Any collagen trimer that passes through a lipid bilayer membrane.	tmpzr1t_l9r_go_relaxed.owl	MACIT													cellular_component											owl:Class	
GO:0022803	biolink:NamedThing	passive transmembrane transporter activity	Enables the transfer of a single solute from one side of a membrane to the other by a mechanism involving conformational change, either by facilitated diffusion or in a membrane potential dependent process if the solute is charged.	tmpzr1t_l9r_go_relaxed.owl	porters|facilitated diffusion|uniporter activity z				Wikipedia:Facilitated_diffusion|Reactome:R-HSA-429767							GO:0022814		molecular_function											owl:Class	
GO:0000708	biolink:NamedThing	meiotic strand invasion	The cell cycle process in which the nucleoprotein complex (composed of the broken single-strand DNA and the recombinase) searches and identifies a region of homology in intact duplex DNA. The broken single-strand DNA displaces the like strand and forms Watson-Crick base pairs with its complement, forming a duplex in which each strand is from one of the two recombining DNA molecules. This occurs during meiosis.	tmpzr1t_l9r_go_relaxed.owl	meiotic displacement loop formation|meiotic D-loop biosynthesis|meiotic D-loop formation|meiotic displacement loop biosynthesis													biological_process											owl:Class	
GO:0042148	biolink:NamedThing	strand invasion	The process in which the nucleoprotein complex (composed of the broken single-strand DNA and the recombinase) searches and identifies a region of homology in intact duplex DNA. The broken single-strand DNA displaces the like strand and forms Watson-Crick base pairs with its complement, forming a duplex in which each strand is from one of the two recombining DNA molecules.	tmpzr1t_l9r_go_relaxed.owl	displacement loop formation|D-loop formation|Rad51-mediated strand invasion|displacement loop biosynthesis|D-loop biosynthesis													biological_process											owl:Class	
GO:1901776	biolink:NamedThing	mitomycin C catabolic process	The chemical reactions and pathways resulting in the breakdown of mitomycin C.	tmpzr1t_l9r_go_relaxed.owl	mitomycin C degradation|mitomycin C catabolism|mitomycin C breakdown							yaf	2013-01-15T12:11:52Z					biological_process											owl:Class	
GO:0140007	biolink:NamedThing	KICSTOR complex	A protein complex that regulates the TORC1 signaling pathway in response to nutrients. The KICSTOR complex is composed of KPTN, ITFG2, C12orf66 and SZT2.	tmpzr1t_l9r_go_relaxed.owl								pg	2017-03-10T12:47:30Z					cellular_component											owl:Class	
GO:1903113	biolink:NamedThing	copper ion transmembrane transporter complex	A protein complex which is capable of copper ion transmembrane transporter activity.	tmpzr1t_l9r_go_relaxed.owl						An example of this is CusA in E. coli (UniProt symbol P38054) in PMID:23122209 (inferred from direct assay).		bhm	2014-06-10T09:54:48Z					cellular_component											owl:Class	
GO:0050886	biolink:NamedThing	endocrine process	The process that involves the secretion of or response to endocrine hormones. An endocrine hormone is a hormone released into the circulatory system.	tmpzr1t_l9r_go_relaxed.owl	endocrine physiological process|endocrine physiology													biological_process											owl:Class	
GO:0002721	biolink:NamedThing	regulation of B cell cytokine production	Any process that modulates the frequency, rate, or extent of B cell cytokine production.	tmpzr1t_l9r_go_relaxed.owl	regulation of B-lymphocyte cytokine production|regulation of B lymphocyte cytokine production|regulation of B-cell cytokine production													biological_process											owl:Class	
GO:1900729	biolink:NamedThing	regulation of adenylate cyclase-inhibiting opioid receptor signaling pathway	Any process that modulates the frequency, rate or extent of adenylate cyclase-inhibiting opioid receptor signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	regulation of opioid receptor-mediated adenylate cyclase inhibition|regulation of inhibition of adenylate cyclase activity by opioid receptor signaling pathway|regulation of inhibition of adenylate cyclase activity by opioid receptor|regulation of inhibition of adenylate cyclase activity by opioid receptor signalling pathway							bf	2012-05-25T03:20:49Z					biological_process											owl:Class	
GO:0052671	biolink:NamedThing	geranylgeraniol kinase activity	Catalysis of the reaction: geranylgeraniol + nucleoside triphosphate = all-trans-geranyl-geranyl monophosphate + nucleoside diphosphate.	tmpzr1t_l9r_go_relaxed.owl	geranylgeraniol phosphotransferase activity							ai	2011-04-11T03:18:44Z					molecular_function											owl:Class	
GO:0005756	biolink:NamedThing	mitochondrial proton-transporting ATP synthase, central stalk	One of two stalks that connect the catalytic core of the hydrogen-transporting ATP synthase to the mitochondrial membrane-associated F0 proteins; rotates within the catalytic core during catalysis.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0002622	biolink:NamedThing	regulation of B cell antigen processing and presentation	Any process that modulates the frequency, rate, or extent of B cell antigen processing and presentation.	tmpzr1t_l9r_go_relaxed.owl	regulation of B-cell antigen processing and presentation|regulation of B lymphocyte antigen processing and presentation|regulation of B-lymphocyte antigen processing and presentation													biological_process											owl:Class	
GO:0002577	biolink:NamedThing	regulation of antigen processing and presentation	Any process that modulates the frequency, rate, or extent of antigen processing and presentation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0018690	biolink:NamedThing	4-methoxybenzoate monooxygenase (O-demethylating) activity	Catalysis of the reaction: 4-methoxybenzoate + AH(2) + O(2) = 4-hydroxybenzoate + A + formaldehyde + H(2)O.	tmpzr1t_l9r_go_relaxed.owl	4-methoxybenzoate monooxygenase activity|4-methoxybenzoate 4-monooxygenase (O-demethylating)|4-methoxybenzoate,hydrogen-donor:oxygen oxidoreductase (O-demethylating)|4-methoxybenzoate O-demethylase activity|piperonylate-4-O-demethylase activity|p-anisic O-demethylase activity				EC:1.14.99.15|RHEA:18613|KEGG_REACTION:R01306|MetaCyc:1.14.99.15-RXN|UM-BBD_reactionID:r0154									molecular_function											owl:Class	
GO:1902136	biolink:NamedThing	(-)-secoisolariciresinol metabolic process	The chemical reactions and pathways involving (-)-secoisolariciresinol.	tmpzr1t_l9r_go_relaxed.owl	(-)-secoisolariciresinol metabolism							ms	2013-05-21T08:50:19Z					biological_process											owl:Class	
GO:1990519	biolink:NamedThing	pyrimidine nucleotide import into mitochondrion	The process in which a pyrimidine nucleotide is transported across the mitochondrial inner membrane, into the mitochondrial matrix.	tmpzr1t_l9r_go_relaxed.owl	mitochondrial pyrimidine nucleotide import							vw	2014-10-22T10:20:23Z					biological_process											owl:Class	
GO:2000332	biolink:NamedThing	regulation of blood microparticle formation	Any process that modulates the frequency, rate or extent of blood microparticle formation.	tmpzr1t_l9r_go_relaxed.owl	regulation of microparticle generation|regulation of microparticle release							mah	2011-01-31T11:18:11Z					biological_process											owl:Class	
GO:0035754	biolink:NamedThing	B cell chemotaxis	The directed movement of a B cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).	tmpzr1t_l9r_go_relaxed.owl								bf	2011-03-23T10:30:33Z					biological_process											owl:Class	
GO:0110099	biolink:NamedThing	negative regulation of calcium import into the mitochondrion	Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion import into the mitochondrion.	tmpzr1t_l9r_go_relaxed.owl								kmv	2018-02-28T00:42:06Z					biological_process											owl:Class	
GO:0110097	biolink:NamedThing	regulation of calcium import into the mitochondrion	Any process that modulates the frequency, rate or extent of calcium import into the mitochondrion.	tmpzr1t_l9r_go_relaxed.owl								kmv	2018-02-28T00:33:51Z					biological_process											owl:Class	
GO:1900766	biolink:NamedThing	emericellin biosynthetic process	The chemical reactions and pathways resulting in the formation of emericellin.	tmpzr1t_l9r_go_relaxed.owl	Variecoxanthone B formation|emericellin biosynthesis|Variecoxanthone B biosynthesis|Variecoxanthone B synthesis|Variecoxanthone B anabolism|emericellin anabolism|emericellin formation|emericellin synthesis|Variecoxanthone B biosynthetic process							di	2012-06-04T09:18:29Z					biological_process											owl:Class	
GO:0052201	biolink:NamedThing	response to symbiont defenses	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detecting the defenses of a symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0002924	biolink:NamedThing	negative regulation of humoral immune response mediated by circulating immunoglobulin	Any process that stops, prevents, or reduces the frequency, rate, or extent of a humoral immune response mediated by circulating immunoglobulin.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of humoral immune response mediated by circulating immunoglobulin|down regulation of humoral immune response mediated by circulating immunoglobulin|downregulation of humoral immune response mediated by circulating immunoglobulin|inhibition of humoral immune response mediated by circulating immunoglobulin													biological_process											owl:Class	
GO:0002923	biolink:NamedThing	regulation of humoral immune response mediated by circulating immunoglobulin	Any process that modulates the frequency, rate, or extent of a humoral immune response mediated by circulating immunoglobulin.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0000433	biolink:NamedThing	carbon catabolite repression of transcription from RNA polymerase II promoter by glucose	A transcription regulation process in which the presence of glucose leads to a decrease in the frequency, rate, or extent of transcription of specific RNA polymerase II-transcribed genes involved in the metabolism of other carbon sources. Carbon catabolite repression is a mechanism of genetic regulation which the accumulation of catabolites of one substance in the cell represses the formation of enzymes that contribute to the catabolism of other substances.	tmpzr1t_l9r_go_relaxed.owl	inhibition of transcription from RNA polymerase II promoter by glucose|down regulation of transcription from RNA polymerase II promoter by glucose|down-regulation of transcription from RNA polymerase II promoter by glucose|downregulation of transcription from RNA polymerase II promoter by glucose													biological_process											owl:Class	
GO:0045014	biolink:NamedThing	carbon catabolite repression of transcription by glucose	A transcription regulation process in which the presence of glucose leads to a decrease in the frequency, rate, or extent of transcription of specific genes involved in the metabolism of other carbon sources. Carbon catabolite repression is a mechanism of genetic regulation which the accumulation of catabolites of one substance in the cell represses the formation of enzymes that contribute to the catabolism of other substances.	tmpzr1t_l9r_go_relaxed.owl	down regulation of transcription by glucose|glucose effect|downregulation of transcription by glucose|down-regulation of transcription by glucose|glucose repression|inhibition of transcription by glucose													biological_process											owl:Class	
GO:0072554	biolink:NamedThing	blood vessel lumenization	The process in which a developing blood vessel forms an endothelial lumen through which blood will flow.	tmpzr1t_l9r_go_relaxed.owl								mah	2011-01-25T05:19:30Z					biological_process											owl:Class	
GO:0061154	biolink:NamedThing	endothelial tube morphogenesis	The process in which the anatomical structures of a tube are generated and organized from an endothelium. Endothelium refers to the layer of cells lining blood vessels, lymphatics, the heart, and serous cavities, and is derived from bone marrow or mesoderm. Corneal endothelium is a special case, derived from neural crest cells.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-06-15T09:05:00Z					biological_process											owl:Class	
GO:2001298	biolink:NamedThing	N(omega),N(omega)-dimethyl-L-arginine metabolic process	The chemical reactions and pathways involving N(omega),N(omega)-dimethyl-L-arginine, a methyl-L-arginine having two methyl groups both attached to the primary amino moiety of the guanidino group.	tmpzr1t_l9r_go_relaxed.owl	N(omega),N(omega)-dimethyl-L-arginine metabolism							pr	2012-02-14T03:39:59Z					biological_process											owl:Class	
GO:0002885	biolink:NamedThing	positive regulation of hypersensitivity	Any process that activates or increases the frequency, rate, or extent of hypersensitivity.	tmpzr1t_l9r_go_relaxed.owl	stimulation of hypersensitivity|up regulation of hypersensitivity|up-regulation of hypersensitivity|upregulation of hypersensitivity|activation of hypersensitivity													biological_process											owl:Class	
GO:0004051	biolink:NamedThing	arachidonate 5-lipoxygenase activity	Catalysis of the reaction: arachidonate + O2 = (6E,8Z,11Z,14Z)-(5S)-5-hydroperoxycosa-6,8,11,14-tetraenoate.	tmpzr1t_l9r_go_relaxed.owl	delta(5)-lipoxygenase activity|leukotriene-A4 synthase activity|5-delta-lipoxygenase activity|arachidonic acid 5-lipoxygenase activity|leukotriene A4 synthase|delta5-lipoxygenase activity|LTA synthase activity|5-lipoxygenase activity|leukotriene-A(4) synthase activity|arachidonic 5-lipoxygenase activity|5Delta-lipoxygenase activity|arachidonate:oxygen 5-oxidoreductase activity|C-5-lipoxygenase activity				Reactome:R-HSA-9027633|Reactome:R-HSA-9018894|Reactome:R-HSA-9020256|Reactome:R-HSA-9027628|Reactome:R-HSA-9024997|Reactome:R-HSA-266051|Reactome:R-HSA-9027624|Reactome:R-HSA-9020278|Reactome:R-HSA-9026405|Reactome:R-HSA-9025995|Reactome:R-HSA-9020282|Reactome:R-HSA-9026005|EC:1.13.11.34|Reactome:R-HSA-9020277|Reactome:R-HSA-9018859|Reactome:R-HSA-265296|Reactome:R-HSA-9025999|Reactome:R-HSA-9025996|Reactome:R-HSA-9020255|MetaCyc:ARACHIDONATE-5-LIPOXYGENASE-RXN|Reactome:R-HSA-9020251|Reactome:R-HSA-9020264|Reactome:R-HSA-9018863|Reactome:R-HSA-9018858|Reactome:R-HSA-9020259|RHEA:32307									molecular_function											owl:Class	
GO:0050994	biolink:NamedThing	regulation of lipid catabolic process	Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of lipids.	tmpzr1t_l9r_go_relaxed.owl	regulation of lipid degradation|regulation of lipid breakdown|regulation of lipid catabolism													biological_process											owl:Class	
GO:2000283	biolink:NamedThing	negative regulation of cellular amino acid biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of cellular amino acid biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of cellular amino acid anabolism|negative regulation of cellular amino acid biosynthesis|negative regulation of cellular amino acid synthesis|negative regulation of cellular amino acid formation|negative regulation of amino acid biosynthetic process							vw	2010-12-10T11:54:23Z					biological_process											owl:Class	
GO:2000282	biolink:NamedThing	regulation of cellular amino acid biosynthetic process	Any process that modulates the frequency, rate or extent of cellular amino acid biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of cellular amino acid formation|regulation of cellular amino acid anabolism|regulation of cellular amino acid biosynthesis|regulation of cellular amino acid synthesis|regulation of amino acid biosynthetic process							vw	2010-12-10T11:54:19Z					biological_process											owl:Class	
GO:0032399	biolink:NamedThing	HECT domain binding	Binding to a HECT, 'Homologous to the E6-AP Carboxy-Terminus', domain of a protein.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0090435	biolink:NamedThing	protein localization to nuclear envelope	A process in which a protein is transported to, or maintained at, a location within a nuclear envelope.	tmpzr1t_l9r_go_relaxed.owl	protein localization in nuclear envelope							tb	2012-07-30T01:50:41Z					biological_process											owl:Class	
GO:2000097	biolink:NamedThing	regulation of smooth muscle cell-matrix adhesion	Any process that modulates the frequency, rate or extent of smooth muscle cell-matrix adhesion.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-09-14T04:22:20Z					biological_process											owl:Class	
GO:0010189	biolink:NamedThing	vitamin E biosynthetic process	The chemical reactions and pathways resulting in the formation of vitamin E, tocopherol, which includes a series of eight structurally similar compounds. Alpha-tocopherol is the most active form in humans and is a powerful biological antioxidant.	tmpzr1t_l9r_go_relaxed.owl	alpha-tocopherol biosynthetic process|vitamin E biosynthesis|alpha-tocopherol biosynthesis|tocopherol biosynthesis|vitamin E anabolism|tocopherol biosynthetic process|vitamin E synthesis|vitamin E formation				MetaCyc:PWY-1422									biological_process											owl:Class	
GO:0035487	biolink:NamedThing	thymine/thymine mispair binding	Binding to a double-stranded DNA region containing a T/T mispair.	tmpzr1t_l9r_go_relaxed.owl	T/T mispair binding							bf	2010-04-23T10:56:37Z					molecular_function											owl:Class	
GO:0043553	biolink:NamedThing	negative regulation of phosphatidylinositol 3-kinase activity	Any process that stops, prevents, or reduces the frequency, rate or extent of phosphatidylinositol 3-kinase activity.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of phosphatidylinositol 3-kinase activity|negative regulation of PI3K activity|inhibition of phosphatidylinositol 3-kinase activity|downregulation of phosphatidylinositol 3-kinase activity|down regulation of phosphatidylinositol 3-kinase activity|negative regulation of phosphoinositide 3-kinase activity													biological_process											owl:Class	
GO:2000406	biolink:NamedThing	positive regulation of T cell migration	Any process that activates or increases the frequency, rate or extent of T cell migration.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of T lymphocyte migration|positive regulation of T-lymphocyte migration|positive regulation of T-cell migration							mah	2011-02-23T10:49:12Z					biological_process											owl:Class	
GO:0017004	biolink:NamedThing	cytochrome complex assembly	The aggregation, arrangement and bonding together of a cytochrome complex. A cytochrome complex is a protein complex in which at least one of the proteins is a cytochrome, i.e. a heme-containing protein involved in catalysis of redox reactions.	tmpzr1t_l9r_go_relaxed.owl	cytochrome biogenesis													biological_process											owl:Class	
GO:0039513	biolink:NamedThing	suppression by virus of host catalytic activity	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host enzyme activity.	tmpzr1t_l9r_go_relaxed.owl	inhibition by virus of host catalytic activity|down-regulation by virus of host enzyme activity|negative regulation by virus of host catalytic activity|downregulation by virus of host catalytic activity							bf	2011-06-16T02:32:49Z					biological_process											owl:Class	
GO:1905171	biolink:NamedThing	positive regulation of protein localization to phagocytic vesicle	Any process that activates or increases the frequency, rate or extent of protein localization to phagocytic vesicle.	tmpzr1t_l9r_go_relaxed.owl	up regulation of protein localisation to phagocytic vesicle|upregulation of protein localization to phagocytic vesicle|activation of protein localization in phagocytic vesicle|activation of protein localisation to phagosome|upregulation of protein localization in phagocytic vesicle|up regulation of protein localisation to phagosome|upregulation of protein localisation to phagocytic vesicle|up-regulation of protein localisation to phagocytic vesicle|upregulation of protein localisation to phagosome|upregulation of protein recruitment to phagosome|up-regulation of protein localisation in phagocytic vesicle|positive regulation of protein localisation to phagosome|upregulation of protein localisation in phagocytic vesicle|up-regulation of protein recruitment to phagosome|up regulation of protein localization to phagocytic vesicle|up regulation of protein recruitment to phagosome|up-regulation of protein localisation to phagosome|activation of protein recruitment to phagosome|activation of protein localization to phagocytic vesicle|up-regulation of protein localization in phagocytic vesicle|positive regulation of protein localisation to phagocytic vesicle|activation of protein localisation in phagocytic vesicle|positive regulation of protein recruitment to phagosome|positive regulation of protein localization in phagocytic vesicle|positive regulation of protein localisation in phagocytic vesicle|up-regulation of protein localization to phagocytic vesicle|activation of protein localisation to phagocytic vesicle|up regulation of protein localisation in phagocytic vesicle|up regulation of protein localization in phagocytic vesicle							bf	2016-05-02T18:38:30Z					biological_process											owl:Class	
GO:2001199	biolink:NamedThing	negative regulation of dendritic cell differentiation	Any process that stops, prevents or reduces the frequency, rate or extent of dendritic cell differentiation.	tmpzr1t_l9r_go_relaxed.owl								yaf	2011-11-04T02:01:33Z					biological_process											owl:Class	
GO:2001198	biolink:NamedThing	regulation of dendritic cell differentiation	Any process that modulates the frequency, rate or extent of dendritic cell differentiation.	tmpzr1t_l9r_go_relaxed.owl								yaf	2011-11-04T02:01:27Z					biological_process											owl:Class	
GO:0052648	biolink:NamedThing	ribitol phosphate metabolic process	The chemical reactions and pathways involving ribitol phosphates, any phosphorylated form of ribitol, the pentitol derived formally by reduction of the -CHO group of either D- or L-ribose.	tmpzr1t_l9r_go_relaxed.owl	ribitol phosphate metabolism							ai	2010-09-22T04:28:37Z					biological_process											owl:Class	
GO:0052647	biolink:NamedThing	pentitol phosphate metabolic process	The chemical reactions and pathways involving pentitol phosphates, any phosphorylated alditol with a chain of five carbon atoms in the molecule.	tmpzr1t_l9r_go_relaxed.owl	pentitol phosphate metabolism							ai	2010-09-22T04:26:28Z					biological_process											owl:Class	
GO:0010561	biolink:NamedThing	negative regulation of glycoprotein biosynthetic process	Any process that decreases the rate, frequency, or extent of the chemical reactions and pathways resulting in the formation of a glycoprotein, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0021516	biolink:NamedThing	dorsal spinal cord development	The process whose specific outcome is the progression of the dorsal region of the spinal cord over time, from its formation to the mature structure. The dorsal region of the mature spinal cord contains neurons that process and relay sensory input.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0102289	biolink:NamedThing	beta-amyrin 11-oxidase activity	Catalysis of the reaction: beta-amyrin + 2 O2 + 2 NADPH + 2 H+ <=> 11-oxo-beta-amyrin + 3 H2O + 2 NADP.	tmpzr1t_l9r_go_relaxed.owl					RHEA:31711|EC:1.14.14.152|MetaCyc:RXN-12680									molecular_function											owl:Class	
GO:0018342	biolink:NamedThing	protein prenylation	The covalent attachment of a prenyl group to a protein; geranyl, farnesyl, or geranylgeranyl groups may be added.	tmpzr1t_l9r_go_relaxed.owl	C-terminal protein prenylation|protein amino acid prenylation											GO:0018346		biological_process											owl:Class	
GO:0001695	biolink:NamedThing	histamine catabolic process	The chemical reactions and pathways resulting in the breakdown of histamine, a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans.	tmpzr1t_l9r_go_relaxed.owl	histamine breakdown|histamine degradation|histamine catabolism													biological_process											owl:Class	
GO:1990734	biolink:NamedThing	astral microtubule anchoring at mitotic spindle pole body	Any process in which an astral microtubule is maintained in a specific location in a cell by attachment to a mitotic spindle pole body. Microtubules attach to spindle pole bodies at the minus end.	tmpzr1t_l9r_go_relaxed.owl								vw	2015-04-28T12:15:18Z					biological_process											owl:Class	
GO:0033859	biolink:NamedThing	furaldehyde metabolic process	The chemical reactions and pathways involving furaldehyde, a furan ring-containing aldehyde compound which can be formed from the thermal decomposition of biomass.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0010134	biolink:NamedThing	sulfate assimilation via adenylyl sulfate reduction	The pathway by which inorganic sulfate is activated, reduced and incorporated into sulfated compounds, where the activated sulfate, adenylyl-sulfate, is reduced to sulfite by the activity of adenylyl-sulfate reductase.	tmpzr1t_l9r_go_relaxed.owl	sulphate assimilation via adenylyl sulphate reduction				MetaCyc:SULFMETII-PWY									biological_process											owl:Class	
GO:0019419	biolink:NamedThing	sulfate reduction	The chemical reactions and pathways resulting in the reduction of sulfate to another sulfur-containing ion or compound such as hydrogen sulfide, adenosine-phosphosulfate (APS) or thiosulfate.	tmpzr1t_l9r_go_relaxed.owl	assimilatory sulphate reduction|sulphate reduction|sulfate reduction, APS pathway|sulphate reduction, APS pathway|assimilatory sulfate reduction											GO:0019421		biological_process											owl:Class	
GO:0097528	biolink:NamedThing	execution phase of necroptosis	A stage of the necroptotic process that starts after a necroptotic signal has been relayed to the execution machinery. Key steps of the execution phase are swelling of organelles, minor ultrastructural modifications of the nucleus (specifically, dilatation of the nuclear membrane and condensation of chromatin into small, irregular, circumscribed patches) and increased cell volume (oncosis), culminating in the disruption of the plasma membrane and subsequent loss of intracellular contents. The execution phase ends when the cell has died.	tmpzr1t_l9r_go_relaxed.owl	necroptosis|execution phase of necroptotic process|necroptotic execution phase							pr	2013-11-05T14:23:53Z					biological_process											owl:Class	
GO:0003155	biolink:NamedThing	BMP signaling pathway involved in determination of lateral mesoderm left/right asymmetry	A series of molecular signals generated as a consequence of any member of the BMP (bone morphogenetic protein) family binding to a cell surface receptor that contributes to the determination of lateral mesoderm left/right asymmetry.	tmpzr1t_l9r_go_relaxed.owl	BMP signalling pathway involved in determination of lateral mesoderm left/right asymmetry|BMP signaling pathway involved in lateral mesoderm left/right asymmetry determination							tb	2009-09-24T05:42:17Z					biological_process											owl:Class	
GO:0048091	biolink:NamedThing	positive regulation of female pigmentation	Any process that activates or increases the frequency, rate or extent of establishment of a pattern of pigment in females.	tmpzr1t_l9r_go_relaxed.owl	stimulation of female pigmentation|activation of female pigmentation|up-regulation of female pigmentation|upregulation of female pigmentation|up regulation of female pigmentation													biological_process											owl:Class	
GO:0061924	biolink:NamedThing	regulation of formation of radial glial scaffolds	Any process that modulates the frequency, rate or extent of the formation of radial glial scaffolds. The scaffolds are used as a substrate for the radial migration of cells.	tmpzr1t_l9r_go_relaxed.owl	regulation of Bergmann fiber formation|regulation of Bergmann fiber biosynthesis|regulation of radial glial scaffold formation							dph	2017-08-02T16:17:31Z					biological_process											owl:Class	
GO:0047971	biolink:NamedThing	guanidinobutyrase activity	Catalysis of the reaction: 4-guanidinobutanoate + H(2)O = 4-aminobutanoate + urea.	tmpzr1t_l9r_go_relaxed.owl	gamma-guanidinobutyrate amidinohydrolase activity|4-guanidinobutyrate amidinobutyrase activity|4-guanidinobutanoate amidinohydrolase activity|G-base activity|gamma-guanidobutyrase activity|GBH|guanidinobutyrate ureahydrolase activity				KEGG_REACTION:R01990|RHEA:19501|MetaCyc:GUANIDINOBUTYRASE-RXN|EC:3.5.3.7									molecular_function											owl:Class	
GO:0070791	biolink:NamedThing	cleistothecium development	The process whose specific outcome is the progression of the cleistothecium over time, from its formation to the mature structure. The cleistothecium is a closed sexual fruiting body that contains ascospores in linear asci, characteristic of some filamentous Ascomycete fungi such as members of the genera Aspergillus and Emericella.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-07-08T02:52:32Z					biological_process											owl:Class	
GO:0000909	biolink:NamedThing	sporocarp development involved in sexual reproduction	The process whose specific outcome is the progression of a fruiting body organ over time, from its formation to the mature structure. The fruiting body is a spore bearing structure. In fungi, the sporocarp (also known as fruiting body) is a multicellular structure on which spore-producing structures, such as basidia or asci, are borne. The fruiting body is part of the sexual phase of a fungal life cycle, with the rest of the life cycle being characterized by vegetative mycelial growth. The sporocarp of a basidiomycete is known as a basidiocarp, while the fruiting body of an ascomycete is known as an ascocarp. A significant range of different shapes and morphologies is found in both basidiocarps and ascocarps; these features play an important role in the identification and taxonomy of fungi.	tmpzr1t_l9r_go_relaxed.owl	fruiting body development involved in sexual reproduction|fruiting body formation involved in sexual reproduction|perfect stage fruiting body development|ascus development													biological_process											owl:Class	
GO:1904047	biolink:NamedThing	S-adenosyl-L-methionine binding	Binding to S-adenosyl-L-methionine.	tmpzr1t_l9r_go_relaxed.owl	radical SAM enzyme activity				Reactome:R-HSA-947535			hal	2015-03-17T10:32:16Z			GO:0070283		molecular_function											owl:Class	
GO:0018674	biolink:NamedThing	(S)-limonene 3-monooxygenase activity	Catalysis of the reaction: (4S)-limonene + H(+) + NADPH + O(2) = (1S,6R)-isopiperitenol + H(2)O + NADP(+).	tmpzr1t_l9r_go_relaxed.owl	(S)-limonene,NADPH:oxygen oxidoreductase (3-hydroxylating)|(-)-limonene,NADPH:oxygen oxidoreductase (3-hydroxylating) activity|(-)-limonene 3-monooxygenase activity|limonene 3-hydroxylase activity|(-)-limonene 3-hydroxylase activity				RHEA:15129|MetaCyc:--LIMONENE-3-MONOOXYGENASE-RXN|KEGG_REACTION:R02469|EC:1.14.14.99|UM-BBD_reactionID:r0739									molecular_function											owl:Class	
GO:0019113	biolink:NamedThing	limonene monooxygenase activity	Catalysis of a monooxygenase reaction in which oxygen is incorporated into limonene.	tmpzr1t_l9r_go_relaxed.owl					EC:1.14.13.-									molecular_function											owl:Class	
GO:0090156	biolink:NamedThing	cellular sphingolipid homeostasis	Any biological process involved in the maintenance of an internal steady state of sphingolipids at the level of the cell.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-12-08T08:21:36Z					biological_process											owl:Class	
GO:0055082	biolink:NamedThing	cellular chemical homeostasis	Any biological process involved in the maintenance of an internal steady state of a chemical at the level of the cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0032880	biolink:NamedThing	regulation of protein localization	Any process that modulates the frequency, rate or extent of any process in which a protein is transported to, or maintained in, a specific location.	tmpzr1t_l9r_go_relaxed.owl	regulation of cellular protein localisation|regulation of cellular protein localization|regulation of protein localisation	https://github.com/geneontology/go-ontology/issues/22021						jl	2015-01-20T14:32:14Z			GO:1903827		biological_process											owl:Class	
GO:0070366	biolink:NamedThing	regulation of hepatocyte differentiation	Any process that modulates the frequency, rate or extent of hepatocyte differentiation.	tmpzr1t_l9r_go_relaxed.owl	regulation of liver cell differentiation													biological_process											owl:Class	
GO:1901532	biolink:NamedThing	regulation of hematopoietic progenitor cell differentiation	Any process that modulates the frequency, rate or extent of hematopoietic progenitor cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	regulation of hemopoietic progenitor cell differentiation|regulation of haematopoietic progenitor cell differentiation|regulation of haemopoietic progenitor cell differentiation							vk	2012-10-24T11:23:01Z					biological_process											owl:Class	
GO:0090081	biolink:NamedThing	regulation of heart induction by regulation of canonical Wnt signaling pathway	Any process that modulates the rate, frequency or extent of canonical Wnt signaling pathway that regulates heart induction. Canonical Wnt signaling pathway involved in heart induction is the series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of the target cell, followed by relaying of the signal via beta-catenin, and ending with a change in transcription of target genes.	tmpzr1t_l9r_go_relaxed.owl	regulation of heart induction by regulation of canonical Wnt receptor signalling pathway|regulation of heart induction by regulation of canonical Wnt receptor signaling pathway|regulation of heart induction by regulation of canonical Wnt-activated signaling pathway							tb	2009-10-23T10:55:18Z					biological_process											owl:Class	
GO:1900386	biolink:NamedThing	positive regulation of flavonol biosynthetic process	Any process that activates or increases the frequency, rate or extent of flavonol biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	activation of flavonol biosynthetic process|upregulation of flavonol biosynthetic process|up-regulation of flavonol biosynthetic process|up regulation of flavonol biosynthetic process							tb	2012-04-17T10:23:09Z					biological_process											owl:Class	
GO:0070980	biolink:NamedThing	biphenyl catabolic process	The chemical reactions and pathways resulting in the breakdown of biphenyl, a toxic aromatic hydrocarbon used as a heat transfer agent, as a fungistat in packaging citrus fruits and in plant disease control. Biphenyl can be chlorinated with 1-10 chlorine molecules to form polychlorinated biphenyls (PCBs).	tmpzr1t_l9r_go_relaxed.owl	biphenyl degradation|biphenyl breakdown|biphenyl catabolism							mah	2009-10-27T11:24:59Z					biological_process											owl:Class	
GO:0031479	biolink:NamedThing	myosin IX complex	A myosin complex containing a class IX myosin heavy chain and associated light chains. Myosin IX is monomeric with a motor domain containing an N-terminal extension and an insert in the actin binding interface, followed by four to six IQ motifs and a tail region that contains a zinc binding motif and a domain with homology to GTPase activating proteins (GAPs) of the Rho family of G-proteins.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0042865	biolink:NamedThing	pyochelin catabolic process	The chemical reactions and pathways resulting in the breakdown of the siderochrome pyochelin (2-(2-o-hydroxyphenyl-2-thiazolin-4-yl)-3-methylthiazolidine-4-carboxylic acid).	tmpzr1t_l9r_go_relaxed.owl	pyochelin breakdown|pyochelin degradation|pyochelin catabolism													biological_process											owl:Class	
GO:0045717	biolink:NamedThing	negative regulation of fatty acid biosynthetic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of fatty acids.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of fatty acid synthesis|negative regulation of fatty acid formation|negative regulation of fatty acid biosynthesis|down regulation of fatty acid biosynthetic process|downregulation of fatty acid biosynthetic process|inhibition of fatty acid biosynthetic process|negative regulation of fatty acid anabolism|down-regulation of fatty acid biosynthetic process													biological_process											owl:Class	
GO:0045922	biolink:NamedThing	negative regulation of fatty acid metabolic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving fatty acids.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of fatty acid metabolism|downregulation of fatty acid metabolic process|inhibition of fatty acid metabolic process|down-regulation of fatty acid metabolic process|down regulation of fatty acid metabolic process													biological_process											owl:Class	
GO:1900672	biolink:NamedThing	positive regulation of F-9775A biosynthetic process	Any process that activates or increases the frequency, rate or extent of F-9775A biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	activation of F-9775A biosynthetic process|positive regulation of F-9775A anabolism|upregulation of F-9775A biosynthesis|up-regulation of F-9775A biosynthetic process|up regulation of F-9775A biosynthesis|upregulation of F-9775A biosynthetic process|activation of F-9775A biosynthesis|activation of F-9775A synthesis|positive regulation of F-9775A biosynthesis|upregulation of F-9775A anabolism|upregulation of F-9775A formation|activation of F-9775A anabolism|activation of F-9775A formation|up regulation of F-9775A formation|up regulation of F-9775A synthesis|up-regulation of F-9775A biosynthesis|up regulation of F-9775A anabolism|up-regulation of F-9775A synthesis|up regulation of F-9775A biosynthetic process|up-regulation of F-9775A anabolism|upregulation of F-9775A synthesis|positive regulation of F-9775A synthesis|up-regulation of F-9775A formation|positive regulation of F-9775A formation							di	2012-05-22T04:24:37Z					biological_process											owl:Class	
GO:0061150	biolink:NamedThing	renal system segmentation	The regionalization process that divides an the renal system into a series of segments along its proximal/distal axis.	tmpzr1t_l9r_go_relaxed.owl	urinary tract segmentation							dph	2010-06-02T09:23:01Z					biological_process											owl:Class	
GO:0072048	biolink:NamedThing	renal system pattern specification	Any developmental process that results in the creation of defined areas or spaces within an organism to which cells respond and eventually are instructed to differentiate into the anatomical structures of the renal system.	tmpzr1t_l9r_go_relaxed.owl	renal system pattern formation							mah	2010-01-25T03:31:51Z					biological_process											owl:Class	
GO:1903882	biolink:NamedThing	negative regulation of interleukin-17-mediated signaling pathway	Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-17-mediated signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of interleukin-17-mediated signaling pathway|down regulation of interleukin-17-mediated signalling pathway|down regulation of interleukin-17-mediated signaling pathway|down-regulation of interleukin-17-mediated signalling pathway|down-regulation of IL-17-mediated signalling pathway|downregulation of IL-17-mediated signalling pathway|down regulation of IL-17-mediated signaling pathway|inhibition of interleukin-17-mediated signalling pathway|negative regulation of interleukin-17-mediated signalling pathway|down regulation of IL-17-mediated signalling pathway|downregulation of interleukin-17-mediated signalling pathway|inhibition of interleukin-17-mediated signaling pathway|downregulation of IL-17-mediated signaling pathway|inhibition of IL-17-mediated signaling pathway|down-regulation of IL-17-mediated signaling pathway|downregulation of interleukin-17-mediated signaling pathway|negative regulation of IL-17-mediated signalling pathway|inhibition of IL-17-mediated signalling pathway|negative regulation of IL-17-mediated signaling pathway							krc	2015-02-06T16:26:47Z					biological_process											owl:Class	
GO:1903881	biolink:NamedThing	regulation of interleukin-17-mediated signaling pathway	Any process that modulates the frequency, rate or extent of interleukin-17-mediated signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	regulation of IL-17-mediated signaling pathway|regulation of interleukin-17-mediated signalling pathway|regulation of IL-17-mediated signalling pathway							krc	2015-02-06T16:26:38Z					biological_process											owl:Class	
GO:0103079	biolink:NamedThing	2-(3'-methylthio)propylmalate synthase activity	Catalysis of the reaction: 5-methylthio-2-oxopentanoate + acetyl-CoA + H2O <=> H+ + 2-(3-methylthiopropyl)malate + coenzyme A.	tmpzr1t_l9r_go_relaxed.owl					RHEA:25605|MetaCyc:RXNQT-4163									molecular_function											owl:Class	
GO:2000116	biolink:NamedThing	regulation of cysteine-type endopeptidase activity	Any process that modulates the frequency, rate or extent of cysteine-type endopeptidase activity.	tmpzr1t_l9r_go_relaxed.owl	regulation of thiol endopeptidase activity|regulation of lysosomal cysteine-type endopeptidase							jl	2010-09-23T10:24:33Z					biological_process											owl:Class	
GO:0052548	biolink:NamedThing	regulation of endopeptidase activity	Any process that modulates the frequency, rate or extent of endopeptidase activity, the endohydrolysis of peptide bonds within proteins.	tmpzr1t_l9r_go_relaxed.owl	protease regulator activity													biological_process											owl:Class	
GO:0002768	biolink:NamedThing	immune response-regulating cell surface receptor signaling pathway	A series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell capable of activating, perpetuating, or inhibiting an immune response.	tmpzr1t_l9r_go_relaxed.owl	immune response-regulating cell surface receptor signalling pathway													biological_process											owl:Class	
GO:0000018	biolink:NamedThing	regulation of DNA recombination	Any process that modulates the frequency, rate or extent of DNA recombination, a DNA metabolic process in which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0004483	biolink:NamedThing	mRNA (nucleoside-2'-O-)-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + m7G(5')pppR-RNA = S-adenosyl-L-homocysteine + m7G(5')pppRm-RNA. R may be guanosine or adenosine.	tmpzr1t_l9r_go_relaxed.owl	messenger ribonucleate nucleoside 2'-methyltransferase activity|S-adenosyl-L-methionine:mRNA (nucleoside-2'-O-)-methyltransferase activity|mRNA (adenosine-2'-O-)-methyltransferase activity|messenger RNA (nucleoside-2'-)-methyltransferase activity				Reactome:R-HSA-9684033|EC:2.1.1.57|Reactome:R-HSA-9684032|Reactome:R-HSA-9694721|Reactome:R-HSA-9694521|Reactome:R-HSA-9684030|MetaCyc:2.1.1.57-RXN|Reactome:R-HSA-9694499									molecular_function											owl:Class	
GO:0008171	biolink:NamedThing	O-methyltransferase activity	Catalysis of the transfer of a methyl group to the oxygen atom of an acceptor molecule.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-5578717|Reactome:R-HSA-5629203|Reactome:R-HSA-6790907|Reactome:R-HSA-5629218|Reactome:R-HSA-5629237|EC:2.1.1.-									molecular_function											owl:Class	
GO:0047161	biolink:NamedThing	tartronate O-hydroxycinnamoyltransferase activity	Catalysis of the reaction: hydroxymalonate + sinapoyl-CoA = CoA + sinapoyltartronate.	tmpzr1t_l9r_go_relaxed.owl	sinapoyl-CoA:2-hydroxymalonate O-(hydroxycinnamoyl)transferase activity|tartronate sinapoyltransferase activity|hydroxycinnamoyl-coenzyme-A:tartronate hydroxycinnamoyltransferase activity				EC:2.3.1.106|MetaCyc:2.3.1.106-RXN|KEGG_REACTION:R03965|RHEA:10952									molecular_function											owl:Class	
GO:0050737	biolink:NamedThing	O-hydroxycinnamoyltransferase activity	Catalysis of the transfer of a hydroxycinnamoyl group to an oxygen atom on the acceptor molecule.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0035450	biolink:NamedThing	extrinsic component of lumenal side of plastid thylakoid membrane	The component of a plastid thylakoid membrane consisting of gene products and protein complexes that are loosely bound to its lumenal surface, but not integrated into the hydrophobic region.	tmpzr1t_l9r_go_relaxed.owl	extrinsic to lumenal leaflet of plastid thylakoid membrane|extrinsic to lumenal side of plastid thylakoid membrane|peripheral to lumenal side of plastid thylakoid membrane							bf	2010-04-16T10:17:25Z					cellular_component											owl:Class	
GO:1902557	biolink:NamedThing	5'-adenylyl sulfate transmembrane transporter activity	Enables the transfer of 5'-adenylyl sulfate from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl						An example of this is the YPR011C gene product in S. cerevisiae in PMID:24296033.		mcc	2013-12-09T23:08:05Z					molecular_function											owl:Class	
GO:0047030	biolink:NamedThing	4-hydroxycyclohexanecarboxylate dehydrogenase activity	Catalysis of the reaction: trans-4-hydroxycyclohexanecarboxylate + NAD(+) = 4-oxocyclohexanecarboxylate + H(+) + NADH.	tmpzr1t_l9r_go_relaxed.owl	trans-4-hydroxycyclohexanecarboxylate:NAD+ 4-oxidoreductase activity|trans-4-hydroxycyclohexanecarboxylate dehydrogenase activity				MetaCyc:1.1.1.226-RXN|EC:1.1.1.226|RHEA:17429|KEGG_REACTION:R04307									molecular_function											owl:Class	
GO:1905147	biolink:NamedThing	regulation of smooth muscle hypertrophy	Any process that modulates the frequency, rate or extent of smooth muscle hypertrophy.	tmpzr1t_l9r_go_relaxed.owl								bc	2016-04-15T12:47:07Z					biological_process											owl:Class	
GO:0014743	biolink:NamedThing	regulation of muscle hypertrophy	Any process that modulates the frequency, rate or extent of muscle hypertrophy.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0018864	biolink:NamedThing	acetylene metabolic process	The chemical reactions and pathways involving acetylene, formula CH2CH2, the simplest of the alkynes.	tmpzr1t_l9r_go_relaxed.owl	ethyne metabolism|acetylene metabolism|ethyne metabolic process				UM-BBD_pathwayID:atl									biological_process											owl:Class	
GO:0045201	biolink:NamedThing	maintenance of neuroblast polarity	The maintenance of the apicobasal polarity of a neuroblast cell, a progenitor of the central nervous system.	tmpzr1t_l9r_go_relaxed.owl	maintenance of neuroblast cell polarity											GO:0043344|GO:0043341		biological_process											owl:Class	
GO:0045196	biolink:NamedThing	establishment or maintenance of neuroblast polarity	Any cellular process that results in the specification, formation or maintenance of the apicobasal polarity of a neuroblast cell, a progenitor of the central nervous system.	tmpzr1t_l9r_go_relaxed.owl	establishment and/or maintenance of neuroblast cell polarity											GO:0043342|GO:0043339		biological_process											owl:Class	
GO:0060567	biolink:NamedThing	negative regulation of DNA-templated transcription, termination	Any process that decreases the rate, frequency or extent of DNA-dependent transcription termination, the process in which transcription is completed; the formation of phosphodiester bonds ceases, the RNA-DNA hybrid dissociates, and RNA polymerase releases the DNA.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of transcription termination, DNA-dependent|negative regulation of termination of DNA-dependent transcription|negative regulation of DNA-dependent transcription, termination							dph	2009-04-29T02:59:12Z					biological_process											owl:Class	
GO:0020035	biolink:NamedThing	cytoadherence to microvasculature, mediated by symbiont protein	The adherence of symbiont-infected erythrocytes to microvascular endothelium via symbiont proteins embedded in the membrane of the erythrocyte.	tmpzr1t_l9r_go_relaxed.owl	heterophilic cell adhesion involved in cytoadherence to microvasculature, mediated by parasite protein|parasite-protein-mediated cytoadherence to microvasculature|symbiont-protein-mediated cytoadherence to microvasculature|cytoadherence to microvasculature, mediated by parasite protein	https://github.com/geneontology/go-ontology/issues/18814										GO:0043706		biological_process											owl:Class	
GO:0044406	biolink:NamedThing	adhesion of symbiont to host	The attachment of a symbiont to its host via adhesion molecules, general stickiness etc., either directly or indirectly. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	adhesion to other organism involved in symbiotic interaction|adhesion to host|adhesion to other organism during symbiotic interaction|host adhesion|adhesion to symbiont					This term can be used to annotate both symbiont and host organisms. Consider also annotating to biological process involved in interaction with symbiont ; GO:0051702.						GO:0051825|GO:0051856		biological_process											owl:Class	
GO:0140473	biolink:NamedThing	telomere-nuclear envelope anchor activity	The binding activity of a molecule that brings together the telomeric region of a chromosome and the inner nuclear membrane by interacting with both the telomere and the nuclear membrane, in order to establish and maintain the telomeric location.	tmpzr1t_l9r_go_relaxed.owl	nuclear envelope-telomere anchor activity|telomere-nuclear envelope anchoring activity	https://github.com/geneontology/go-ontology/issues/19229						pg	2020-06-19T15:44:44Z					molecular_function											owl:Class	
GO:1990690	biolink:NamedThing	Golgi medial cisterna-derived vesicle fusion with Golgi cis cisterna membrane	The joining of the lipid bilayer membrane around a Golgi medial cisterna-derived vesicle to the lipid bilayer membrane around the Golgi cis cisterna. Such vesicles include COPI-coated transport vesicles involved in retrograde transport.	tmpzr1t_l9r_go_relaxed.owl	medial-Golgi cisterna-derived vesicle fusion with cis-Golgi cisterna membrane							bhm	2015-03-12T09:47:03Z					biological_process											owl:Class	
GO:0048210	biolink:NamedThing	Golgi vesicle fusion to target membrane	The joining of the lipid bilayer membrane around a Golgi transport vesicle to the target lipid bilayer membrane.	tmpzr1t_l9r_go_relaxed.owl	dictyosome vesicle fusion to target membrane|Golgi-derived vesicle fusion to target membrane													biological_process											owl:Class	
GO:1904776	biolink:NamedThing	regulation of protein localization to cell cortex	Any process that modulates the frequency, rate or extent of protein localization to cell cortex.	tmpzr1t_l9r_go_relaxed.owl	regulation of protein localisation to cell cortex					An example is cye-1 in C. elegans, UniProt ID O01501 in PMID:17115027.		es	2015-10-29T16:55:01Z					biological_process											owl:Class	
GO:1900719	biolink:NamedThing	regulation of uterine smooth muscle relaxation	Any process that modulates the frequency, rate or extent of uterine smooth muscle relaxation.	tmpzr1t_l9r_go_relaxed.owl	regulation of smooth muscle relaxation of the uterus							jl	2012-05-24T03:12:26Z					biological_process											owl:Class	
GO:0015594	biolink:NamedThing	ABC-type putrescine transporter activity	Catalysis of the reaction: ATP + H2O + putrescine(out) -> ADP + phosphate + putrescine(in).	tmpzr1t_l9r_go_relaxed.owl	ATPase-coupled putrescine transmembrane transporter activity|putrescine-importing ATPase activity|putrescine porter activity				RHEA:29995|EC:7.6.2.16									molecular_function											owl:Class	
GO:0015489	biolink:NamedThing	putrescine transmembrane transporter activity	Enables the transfer of putrescine from one side of a membrane to the other. Putrescine is 1,4-diaminobutane, the polyamine formed by decarboxylation of ornithine and the metabolic precursor of spermidine and spermine.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0071320	biolink:NamedThing	cellular response to cAMP	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate) stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to 3',5' cAMP|cellular response to cyclic AMP|cellular response to 3',5'-cAMP|cellular response to adenosine 3',5'-cyclophosphate							mah	2009-12-10T05:12:15Z					biological_process											owl:Class	
GO:0008804	biolink:NamedThing	carbamate kinase activity	Catalysis of the reaction: ATP + NH3 + CO2 = ADP + carbamoyl phosphate.	tmpzr1t_l9r_go_relaxed.owl	carbamyl phosphokinase activity|ATP:carbamate phosphotransferase activity|carbamoyl phosphokinase activity|CKase activity				EC:2.7.2.2|RHEA:10152|MetaCyc:CARBAMATE-KINASE-RXN									molecular_function											owl:Class	
GO:0019340	biolink:NamedThing	dibenzofuran catabolic process	The chemical reactions and pathways resulting in the breakdown of dibenzofuran, a substance composed of two benzene rings linked by one ether bond and one carbon-carbon bond.	tmpzr1t_l9r_go_relaxed.owl	dibenzofuran breakdown|dibenzofuran catabolism|dibenzofuran degradation				MetaCyc:P662-PWY									biological_process											owl:Class	
GO:1904965	biolink:NamedThing	regulation of vitamin E biosynthetic process	Any process that modulates the frequency, rate or extent of vitamin E biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of vitamin E synthesis|regulation of tocopherol biosynthesis|regulation of alpha-tocopherol biosynthesis|regulation of alpha-tocopherol biosynthetic process|regulation of vitamin E formation|regulation of vitamin E biosynthesis|regulation of vitamin E anabolism|regulation of tocopherol biosynthetic process							tb	2016-02-12T17:56:55Z					biological_process											owl:Class	
GO:1904704	biolink:NamedThing	positive regulation of protein localization to adherens junction	Any process that activates or increases the frequency, rate or extent of protein localization to adherens junction. An adherens junction is a cell-cell junction composed of the epithelial cadherin-catenin complex at which the cytoplasmic face of the plasma membrane is attached to actin filaments.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of protein localization in cell-cell adherens junction|up regulation of protein localization to cell-cell adherens junction|upregulation of protein localization in cell-cell adherens junction|up regulation of protein localisation to cell-cell adherens junction|positive regulation of protein localisation in cell-cell adherens junction|activation of protein localization in cell-cell adherens junction|up-regulation of protein localization to cell-cell adherens junction|up-regulation of protein localization in cell-cell adherens junction|upregulation of protein localization to cell-cell adherens junction|up-regulation of protein localisation to cell-cell adherens junction|upregulation of protein localisation to cell-cell adherens junction|upregulation of protein localisation in cell-cell adherens junction|activation of protein localisation to cell-cell adherens junction|activation of protein localization to cell-cell adherens junction|positive regulation of protein localisation to cell-cell adherens junction|up-regulation of protein localisation in cell-cell adherens junction|up regulation of protein localization in cell-cell adherens junction|activation of protein localisation in cell-cell adherens junction|up regulation of protein localisation in cell-cell adherens junction							kmv	2015-10-01T15:12:02Z					biological_process											owl:Class	
GO:1902896	biolink:NamedThing	terminal web assembly	The aggregation, arrangement and bonding together of a set of components to form a terminal web.	tmpzr1t_l9r_go_relaxed.owl	terminal web formation							kmv	2014-04-08T15:15:25Z					biological_process											owl:Class	
GO:0009786	biolink:NamedThing	regulation of asymmetric cell division	Any process that modulates the frequency, rate or extent of asymmetric cell division.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0016273	biolink:NamedThing	arginine N-methyltransferase activity	Enables the transfer of a methyl group from S-adenosyl-L-methionine to an amino group of an arginine residue.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0008260	biolink:NamedThing	3-oxoacid CoA-transferase activity	Catalysis of the reaction: succinyl-CoA + a 3-oxo acid = succinate + a 3-oxo-acyl-CoA.	tmpzr1t_l9r_go_relaxed.owl	3-oxoacid CoA dehydrogenase activity|3-ketoacid coenzyme A transferase activity|succinyl coenzyme A-acetoacetyl coenzyme A-transferase activity|3-oxo-CoA transferase activity|succinyl-CoA:3-ketoacid-CoA transferase activity|succinyl-CoA transferase activity|acetoacetate succinyl-CoA transferase activity|acetoacetyl coenzyme A-succinic thiophorase activity|3-ketoacid CoA-transferase activity|succinyl-CoA:3-oxo-acid CoA-transferase activity|3-oxoacid coenzyme A-transferase activity				MetaCyc:3-OXOACID-COA-TRANSFERASE-RXN|EC:2.8.3.5|RHEA:25480|Reactome:R-HSA-74177									molecular_function											owl:Class	
GO:0008410	biolink:NamedThing	CoA-transferase activity	Catalysis of the transfer of a coenzyme A (CoA) group from one compound (donor) to another (acceptor).	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-70713|EC:2.8.3.-									molecular_function											owl:Class	
GO:0102172	biolink:NamedThing	4alpha-hydroxymethyl,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(241)-en-3beta-ol-4alpha-methyl oxidase activity	Catalysis of the reaction: 4alpha-hydroxymethyl,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(241)-en-3beta-ol + NADH + O2 + H+ <=> 4alpha-formyl,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(241)-en-3beta-ol + NAD + 2 H2O.	tmpzr1t_l9r_go_relaxed.owl					RHEA:58860|MetaCyc:RXN-11925									molecular_function											owl:Class	
GO:0038137	biolink:NamedThing	ERBB4-EGFR signaling pathway	A series of molecular signals transmitted by a heterodimeric complex of the tyrosine kinase receptors EGFR (epidermal growth factor receptor/ERBB1) and ERBB4. The pathway begins with binding of a ligand to either cell surface receptor, or the dimeric receptor complex, and ends with regulation of a downstream cellular process, e.g. transcription.	tmpzr1t_l9r_go_relaxed.owl	ERBB4-EGFR signalling pathway|HER1-HER4 signaling pathway|ERBB1-ERBB4 signaling pathway							bf	2012-03-30T11:30:30Z					biological_process											owl:Class	
GO:0009136	biolink:NamedThing	purine nucleoside diphosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of purine nucleoside diphosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with diphosphate on the sugar.	tmpzr1t_l9r_go_relaxed.owl	purine nucleoside diphosphate biosynthesis|purine nucleoside diphosphate formation|purine nucleoside diphosphate synthesis|purine nucleoside diphosphate anabolism													biological_process											owl:Class	
GO:0009133	biolink:NamedThing	nucleoside diphosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of a nucleoside diphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with diphosphate on the sugar.	tmpzr1t_l9r_go_relaxed.owl	nucleoside diphosphate formation|nucleoside diphosphate anabolism|nucleoside diphosphate synthesis|nucleoside diphosphate biosynthesis													biological_process											owl:Class	
GO:0043917	biolink:NamedThing	ribose 1,5-bisphosphate isomerase activity	Catalysis of the reaction: D-ribose 1,5-bisphosphate = D-ribulose 1,5-bisphosphate.	tmpzr1t_l9r_go_relaxed.owl	ribose-1,5-bisphosphate isomerase activity				EC:5.3.1.29|MetaCyc:RXN-8801|RHEA:32243									molecular_function											owl:Class	
GO:0071057	biolink:NamedThing	alphav-beta3 integrin-ADAM15 complex	A protein complex that consists of an alphav-beta3 integrin complex bound to the transmembrane metallopeptidase ADAM15.	tmpzr1t_l9r_go_relaxed.owl	ITGAV-ITGB3-ADAM15 complex							mah	2009-11-03T04:00:14Z					cellular_component											owl:Class	
GO:1903964	biolink:NamedThing	monounsaturated fatty acid metabolic process	The chemical reactions and pathways involving monounsaturated fatty acid.	tmpzr1t_l9r_go_relaxed.owl	monounsaturated fatty acid metabolism					For example, stearoyl-coenzyme A desaturase (Scd) catalyzes the desaturation of saturated fatty acids to monounsaturated fatty acids in mammals and yeast.		pr	2015-02-25T20:35:48Z					biological_process											owl:Class	
GO:0033357	biolink:NamedThing	L-arabinose biosynthetic process	The chemical reactions and pathways resulting in the formation of L-arabinose, arabino-pentose.	tmpzr1t_l9r_go_relaxed.owl	L-arabinose synthesis|L-arabinose biosynthesis|L-arabinose anabolism|L-arabinose formation													biological_process											owl:Class	
GO:0018279	biolink:NamedThing	protein N-linked glycosylation via asparagine	The glycosylation of protein via the N4 atom of peptidyl-asparagine forming N4-glycosyl-L-asparagine; the most common form is N-acetylglucosaminyl asparagine; N-acetylgalactosaminyl asparagine and N4 glucosyl asparagine also occur. This modification typically occurs in extracellular peptides with an N-X-(ST) motif. Partial modification has been observed to occur with cysteine, rather than serine or threonine, in the third position; secondary structure features are important, and proline in the second or fourth positions inhibits modification.	tmpzr1t_l9r_go_relaxed.owl	protein amino acid N-linked glycosylation via asparagine													biological_process											owl:Class	
GO:1902961	biolink:NamedThing	positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process	Any process that activates or increases the frequency, rate or extent of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of aspartate protease activity involved in amyloid precursor protein breakdown|activation of aspartic protease activity involved in amyloid precursor protein degradation|up-regulation of aspartyl protease activity involved in amyloid precursor protein degradation|activation of carboxyl protease activity involved in amyloid precursor protein catabolic process|positive regulation of aspartic protease activity involved in amyloid precursor protein degradation|up regulation of carboxyl protease activity involved in amyloid precursor protein breakdown|upregulation of aspartate protease activity involved in APP catabolic process|upregulation of aspartic protease activity involved in amyloid precursor protein catabolism|activation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process|activation of aspartic-type endopeptidase activity involved in APP catabolism|up-regulation of aspartic endopeptidase activity involved in amyloid precursor protein breakdown|positive regulation of aspartic protease activity involved in amyloid precursor protein breakdown|up regulation of aspartic endopeptidase activity involved in amyloid precursor protein breakdown|activation of aspartic endopeptidase activity involved in amyloid precursor protein breakdown|positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein degradation|up regulation of aspartate protease activity involved in APP catabolic process|up-regulation of aspartate protease activity involved in amyloid precursor protein catabolic process|up-regulation of aspartic endopeptidase activity involved in amyloid precursor protein degradation|up-regulation of aspartic protease activity involved in amyloid precursor protein degradation|upregulation of aspartyl protease activity involved in APP catabolic process|upregulation of aspartic endopeptidase activity involved in amyloid precursor protein breakdown|up regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein breakdown|up regulation of aspartate protease activity involved in amyloid precursor protein breakdown|activation of aspartic-type endopeptidase activity involved in amyloid precursor protein degradation|up regulation of aspartic endopeptidase activity involved in APP catabolism|up regulation of aspartyl protease activity involved in amyloid precursor protein degradation|positive regulation of aspartate protease activity involved in amyloid precursor protein degradation|upregulation of aspartic endopeptidase activity involved in amyloid precursor protein catabolism|upregulation of aspartyl protease activity involved in amyloid precursor protein catabolic process|up-regulation of aspartyl protease activity involved in APP catabolism|activation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolism|up-regulation of carboxyl protease activity involved in amyloid precursor protein catabolism|upregulation of aspartic protease activity involved in amyloid precursor protein catabolic process|upregulation of aspartic protease activity involved in APP catabolism|upregulation of carboxyl protease activity involved in amyloid precursor protein catabolism|up-regulation of aspartic-type endopeptidase activity involved in APP catabolic process|up-regulation of carboxyl protease activity involved in APP catabolism|activation of aspartic protease activity involved in APP catabolism|positive regulation of aspartate protease activity involved in amyloid precursor protein catabolic process|positive regulation of carboxyl protease activity involved in APP catabolism|activation of aspartic endopeptidase activity involved in APP catabolic process|activation of carboxyl protease activity involved in amyloid precursor protein catabolism|upregulation of aspartic-type endopeptidase activity involved in APP catabolism|positive regulation of carboxyl protease activity involved in amyloid precursor protein degradation|activation of aspartic-type endopeptidase activity involved in APP catabolic process|up regulation of aspartic-type endopeptidase activity involved in APP catabolic process|up-regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolism|activation of aspartic protease activity involved in APP catabolic process|positive regulation of carboxyl protease activity involved in amyloid precursor protein catabolic process|activation of aspartate protease activity involved in APP catabolism|up regulation of aspartyl protease activity involved in amyloid precursor protein catabolic process|up regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolism|upregulation of aspartate protease activity involved in amyloid precursor protein catabolic process|activation of aspartyl protease activity involved in amyloid precursor protein degradation|positive regulation of carboxyl protease activity involved in amyloid precursor protein breakdown|up regulation of aspartic protease activity involved in amyloid precursor protein breakdown|upregulation of aspartic protease activity involved in APP catabolic process|up-regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein breakdown|positive regulation of aspartyl protease activity involved in amyloid precursor protein breakdown|up regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein degradation|activation of carboxyl protease activity involved in APP catabolism|activation of aspartate protease activity involved in amyloid precursor protein breakdown|positive regulation of aspartic protease activity involved in APP catabolism|up-regulation of carboxyl protease activity involved in amyloid precursor protein breakdown|up regulation of aspartate protease activity involved in amyloid precursor protein catabolism|positive regulation of aspartate protease activity involved in amyloid precursor protein catabolism|up-regulation of aspartic protease activity involved in APP catabolism|up regulation of carboxyl protease activity involved in APP catabolic process|positive regulation of aspartic endopeptidase activity involved in APP catabolism|upregulation of aspartic endopeptidase activity involved in amyloid precursor protein degradation|positive regulation of aspartic protease activity involved in amyloid precursor protein catabolism|activation of aspartate protease activity involved in amyloid precursor protein degradation|up regulation of carboxyl protease activity involved in amyloid precursor protein degradation|up-regulation of aspartic-type endopeptidase activity involved in APP catabolism|positive regulation of aspartic endopeptidase activity involved in amyloid precursor protein breakdown|activation of aspartyl protease activity involved in amyloid precursor protein catabolism|upregulation of aspartic endopeptidase activity involved in amyloid precursor protein catabolic process|upregulation of aspartic endopeptidase activity involved in APP catabolism|activation of carboxyl protease activity involved in APP catabolic process|up-regulation of aspartic protease activity involved in amyloid precursor protein catabolic process|upregulation of carboxyl protease activity involved in amyloid precursor protein catabolic process|activation of carboxyl protease activity involved in amyloid precursor protein degradation|up regulation of aspartic protease activity involved in amyloid precursor protein catabolic process|positive regulation of aspartyl protease activity involved in APP catabolic process|activation of aspartate protease activity involved in amyloid precursor protein catabolism|up regulation of aspartate protease activity involved in amyloid precursor protein degradation|up regulation of aspartyl protease activity involved in APP catabolism|upregulation of carboxyl protease activity involved in APP catabolic process|positive regulation of aspartyl protease activity involved in amyloid precursor protein catabolic process|positive regulation of aspartate protease activity involved in APP catabolic process|up-regulation of aspartate protease activity involved in amyloid precursor protein catabolism|activation of carboxyl protease activity involved in amyloid precursor protein breakdown|up regulation of aspartic protease activity involved in amyloid precursor protein catabolism|up regulation of aspartic endopeptidase activity involved in amyloid precursor protein degradation|up-regulation of aspartyl protease activity involved in amyloid precursor protein catabolism|activation of aspartic protease activity involved in amyloid precursor protein breakdown|activation of aspartic endopeptidase activity involved in amyloid precursor protein catabolism|activation of aspartyl protease activity involved in APP catabolism|up regulation of aspartic endopeptidase activity involved in amyloid precursor protein catabolic process|upregulation of aspartate protease activity involved in amyloid precursor protein breakdown|up regulation of aspartic endopeptidase activity involved in APP catabolic process|up regulation of aspartate protease activity involved in APP catabolism|up-regulation of aspartic endopeptidase activity involved in amyloid precursor protein catabolic process|up regulation of aspartyl protease activity involved in amyloid precursor protein catabolism|positive regulation of aspartic-type endopeptidase activity involved in APP catabolism|activation of aspartic endopeptidase activity involved in APP catabolism|positive regulation of aspartate protease activity involved in APP catabolism|up-regulation of aspartic protease activity involved in amyloid precursor protein catabolism|up regulation of aspartyl protease activity involved in amyloid precursor protein breakdown|upregulation of aspartyl protease activity involved in APP catabolism|up-regulation of aspartate protease activity involved in APP catabolic process|up regulation of carboxyl protease activity involved in amyloid precursor protein catabolism|positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolism|activation of aspartate protease activity involved in APP catabolic process|positive regulation of aspartate protease activity involved in amyloid precursor protein breakdown|positive regulation of aspartic endopeptidase activity involved in amyloid precursor protein catabolic process|upregulation of aspartate protease activity involved in amyloid precursor protein catabolism|up-regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein degradation|up regulation of aspartyl protease activity involved in APP catabolic process|up regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process|up regulation of carboxyl protease activity involved in amyloid precursor protein catabolic process|up-regulation of carboxyl protease activity involved in amyloid precursor protein catabolic process|upregulation of aspartyl protease activity involved in amyloid precursor protein degradation|upregulation of aspartate protease activity involved in APP catabolism|up regulation of aspartic protease activity involved in APP catabolic process|upregulation of aspartyl protease activity involved in amyloid precursor protein breakdown|positive regulation of carboxyl protease activity involved in amyloid precursor protein catabolism|upregulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolism|up-regulation of aspartate protease activity involved in amyloid precursor protein degradation|up regulation of aspartic-type endopeptidase activity involved in APP catabolism|up regulation of aspartate protease activity involved in amyloid precursor protein catabolic process|up-regulation of carboxyl protease activity involved in amyloid precursor protein degradation|up-regulation of aspartyl protease activity involved in APP catabolic process|up-regulation of aspartate protease activity involved in APP catabolism|activation of aspartic protease activity involved in amyloid precursor protein catabolism|upregulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process|activation of aspartyl protease activity involved in amyloid precursor protein catabolic process|up-regulation of aspartic endopeptidase activity involved in APP catabolism|up-regulation of aspartic endopeptidase activity involved in amyloid precursor protein catabolism|positive regulation of aspartyl protease activity involved in amyloid precursor protein catabolism|upregulation of carboxyl protease activity involved in APP catabolism|activation of aspartic endopeptidase activity involved in amyloid precursor protein degradation|upregulation of aspartic-type endopeptidase activity involved in APP catabolic process|up-regulation of aspartyl protease activity involved in amyloid precursor protein breakdown|positive regulation of aspartyl protease activity involved in amyloid precursor protein degradation|upregulation of carboxyl protease activity involved in amyloid precursor protein degradation|upregulation of aspartate protease activity involved in amyloid precursor protein degradation|activation of aspartyl protease activity involved in APP catabolic process|up regulation of carboxyl protease activity involved in APP catabolism|activation of aspartic-type endopeptidase activity involved in amyloid precursor protein breakdown|upregulation of aspartic-type endopeptidase activity involved in amyloid precursor protein breakdown|activation of aspartic endopeptidase activity involved in amyloid precursor protein catabolic process|activation of aspartyl protease activity involved in amyloid precursor protein breakdown|activation of aspartate protease activity involved in amyloid precursor protein catabolic process|positive regulation of carboxyl protease activity involved in APP catabolic process|upregulation of aspartyl protease activity involved in amyloid precursor protein catabolism|positive regulation of aspartic endopeptidase activity involved in amyloid precursor protein catabolism|upregulation of aspartic protease activity involved in amyloid precursor protein breakdown|positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein breakdown|up-regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process|upregulation of aspartic protease activity involved in amyloid precursor protein degradation|up-regulation of carboxyl protease activity involved in APP catabolic process|positive regulation of aspartic endopeptidase activity involved in APP catabolic process|positive regulation of aspartic protease activity involved in APP catabolic process|up regulation of aspartic protease activity involved in amyloid precursor protein degradation|positive regulation of aspartyl protease activity involved in APP catabolism|activation of aspartic protease activity involved in amyloid precursor protein catabolic process|upregulation of aspartic-type endopeptidase activity involved in amyloid precursor protein degradation|up-regulation of aspartic protease activity involved in APP catabolic process|upregulation of aspartic endopeptidase activity involved in APP catabolic process|up-regulation of aspartyl protease activity involved in amyloid precursor protein catabolic process|up regulation of aspartic endopeptidase activity involved in amyloid precursor protein catabolism|positive regulation of aspartic-type endopeptidase activity involved in APP catabolic process|up-regulation of aspartic endopeptidase activity involved in APP catabolic process|positive regulation of aspartic endopeptidase activity involved in amyloid precursor protein degradation|up regulation of aspartic protease activity involved in APP catabolism|up-regulation of aspartic protease activity involved in amyloid precursor protein breakdown|positive regulation of aspartic protease activity involved in amyloid precursor protein catabolic process|upregulation of carboxyl protease activity involved in amyloid precursor protein breakdown							sjp	2014-05-06T09:07:17Z					biological_process											owl:Class	
GO:0019552	biolink:NamedThing	glutamate catabolic process via 2-hydroxyglutarate	The anaerobic chemical reactions and pathways resulting in the breakdown of glutamate, via the intermediate 2-hydroxyglutarate, yielding energy in the form of ATP.	tmpzr1t_l9r_go_relaxed.owl	glutamate fermentation via 2-hydroxyglutarate				MetaCyc:P162-PWY									biological_process											owl:Class	
GO:0019670	biolink:NamedThing	anaerobic glutamate catabolic process	The anaerobic chemical reactions and pathways resulting in the breakdown of glutamate, yielding energy in the form of ATP.	tmpzr1t_l9r_go_relaxed.owl	glutamate fermentation													biological_process											owl:Class	
GO:1905615	biolink:NamedThing	positive regulation of developmental vegetative growth	Any process that activates or increases the frequency, rate or extent of developmental vegetative growth.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of developmental vegetative growth|upregulation of developmental vegetative growth|activation of developmental vegetative growth|up regulation of developmental vegetative growth							pga	2016-10-28T11:45:28Z					biological_process											owl:Class	
GO:0042022	biolink:NamedThing	interleukin-12 receptor complex	A protein complex that binds interleukin-12 and that consists of, at a minimum, a dimeric interleukin and its two receptor subunits as well as optional additional kinase subunits.	tmpzr1t_l9r_go_relaxed.owl	IL12RB1-IL12RB2 complex|IL-12 receptor complex													cellular_component											owl:Class	
GO:0004861	biolink:NamedThing	cyclin-dependent protein serine/threonine kinase inhibitor activity	Binds to and stops, prevents or reduces the activity of a cyclin-dependent protein serine/threonine kinase.	tmpzr1t_l9r_go_relaxed.owl	cyclin dependent protein kinase inhibitor activity|cyclin-dependent protein kinase inhibitor activity|cyclin dependent kinase inhibitor|cyclin-dependent kinase inhibitor|CDK inhibitor				Reactome:R-HSA-69562|Reactome:R-HSA-187934									molecular_function											owl:Class	
GO:0051696	biolink:NamedThing	pointed-end actin filament uncapping	The removal of capping protein from the pointed (or minus) end of actin filaments to free the ends for addition, exchange or removal of further actin subunits.	tmpzr1t_l9r_go_relaxed.owl	pointed-end F-actin uncapping|minus-end actin filament uncapping|minus end actin filament uncapping|minus-end F-actin uncapping|minus end F-actin uncapping|pointed end F-actin uncapping|pointed end actin filament uncapping													biological_process											owl:Class	
GO:0051695	biolink:NamedThing	actin filament uncapping	The removal of capping protein from the end of actin filaments to free the ends for addition, exchange or removal of further actin subunits.	tmpzr1t_l9r_go_relaxed.owl	F-actin uncapping													biological_process											owl:Class	
GO:0030720	biolink:NamedThing	oocyte localization involved in germarium-derived egg chamber formation	Directed movement of the oocyte, following its specification, from its original central position in the cyst to a posterior position relative to the nurse cells of the egg chamber, and its maintenance in this posterior location. This is the first sign of anterior-posterior asymmetry in the developing egg chamber.	tmpzr1t_l9r_go_relaxed.owl	oogenesis, oocyte localization|oocyte positioning during oogenesis|oocyte localization during germarium-derived egg chamber formation|oogenesis, establishment and maintenance of oocyte localization|establishment and maintenance of oocyte localization in egg chamber|oocyte localisation involved in germarium-derived egg chamber formation|establishment and maintenance of oocyte position during oogenesis|oocyte localization during oogenesis													biological_process											owl:Class	
GO:0052649	biolink:NamedThing	coenzyme gamma-F420-2 metabolic process	The chemical reactions and pathways involving coenzyme gamma-F420-2 (F420-2; coenzyme F420; N-{N-[O-(7,8-didemethyl-8-hydroxy-5-deazariboflavin phospho)-(S)-lactyl]-gamma-L-glutamyl}-L-glutamate), the amide obtained by formal condensation of the carboxylic acid group of F420-0 with the amino group of L-gamma-glutamyl-L-glutamic acid.	tmpzr1t_l9r_go_relaxed.owl	coenzyme F420 metabolism|coenzyme gamma-F420-2 metabolism|F420-2 metabolism|F420-2 metabolic process|coenzyme F420 metabolic process							ai	2010-09-22T04:32:35Z					biological_process											owl:Class	
GO:0019391	biolink:NamedThing	glucuronoside catabolic process	The chemical reactions and pathways resulting in the breakdown of glucuronosides, compound composed of a hydroxy compound linked to a glucuronate residue.	tmpzr1t_l9r_go_relaxed.owl	glucuronide catabolism|glucuronoside catabolism|glucuronide catabolic process|glucuronoside breakdown|glucuronoside degradation				MetaCyc:GLUCUROCAT-PWY									biological_process											owl:Class	
GO:0044275	biolink:NamedThing	cellular carbohydrate catabolic process	The chemical reactions and pathways resulting in the breakdown of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y, as carried out by individual cells.	tmpzr1t_l9r_go_relaxed.owl	cellular carbohydrate degradation|cellular carbohydrate breakdown|cellular carbohydrate catabolism													biological_process											owl:Class	
GO:0071305	biolink:NamedThing	cellular response to vitamin D	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin D stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to calciferol|cellular response to cholecalciferol|cellular response to ergocalciferol							mah	2009-12-10T04:35:37Z					biological_process											owl:Class	
GO:0033280	biolink:NamedThing	response to vitamin D	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin D stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to cholecalciferol|response to ergocalciferol|response to calciferol													biological_process											owl:Class	
GO:0071363	biolink:NamedThing	cellular response to growth factor stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth factor stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-12-11T03:05:07Z					biological_process											owl:Class	
GO:0036007	biolink:NamedThing	scintillon	A body present in the cytoplasm of some dinoflagellates, which is the source of bioluminescence; emits light on acidification in the presence of oxygen.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-09-21T03:04:02Z					cellular_component											owl:Class	
GO:0052771	biolink:NamedThing	coenzyme F390-G hydrolase activity	Catalysis of the reaction: coenzyme F390-G = GMP + coenzyme F420.	tmpzr1t_l9r_go_relaxed.owl	8-hydroxyguanylylated-coenzyme F420 hydrolase activity							ai	2011-10-03T12:00:00Z					molecular_function											owl:Class	
GO:0030162	biolink:NamedThing	regulation of proteolysis	Any process that modulates the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein.	tmpzr1t_l9r_go_relaxed.owl	regulation of peptidolysis													biological_process											owl:Class	
GO:2001024	biolink:NamedThing	negative regulation of response to drug	Any process that stops, prevents or reduces the frequency, rate or extent of response to drug.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of drug resistance|negative regulation of drug susceptibility/resistance							yaf	2011-08-19T01:47:24Z					biological_process											owl:Class	
GO:0033022	biolink:NamedThing	cyclopentanol catabolic process	The chemical reactions and pathways resulting in the breakdown of cyclopentanol.	tmpzr1t_l9r_go_relaxed.owl	cyclopentanol breakdown|cyclopentanol degradation|cyclopentanol catabolism													biological_process											owl:Class	
GO:0000716	biolink:NamedThing	transcription-coupled nucleotide-excision repair, DNA damage recognition	The identification of lesions on the actively transcribed strand of the DNA duplex as well as a small subset of lesions not recognized by the general nucleotide-excision repair pathway.	tmpzr1t_l9r_go_relaxed.owl	pyrimidine-dimer repair, DNA damage recognition													biological_process											owl:Class	
GO:0050648	biolink:NamedThing	5(S)-hydroxyperoxy-6E,8Z,11Z,14Z-icosatetraenoic acid binding	Binding to 5(S)-hydroxyperoxy-6E,8Z,11Z,14Z-icosatetraenoic acid, a straight-chain fatty acid with twenty carbon atoms and four double bonds.	tmpzr1t_l9r_go_relaxed.owl	5(S)-hydroxyperoxy-6E,8Z,11Z,14Z-eicosatetraenoic acid binding													molecular_function											owl:Class	
GO:1900385	biolink:NamedThing	negative regulation of flavonol biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of flavonol biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	down regulation of flavonol biosynthetic process|down-regulation of flavonol biosynthetic process|downregulation of flavonol biosynthetic process|inhibition of flavonol biosynthetic process							tb	2012-04-17T10:22:59Z					biological_process											owl:Class	
GO:1903643	biolink:NamedThing	positive regulation of recombination hotspot binding	Any process that activates or increases the frequency, rate or extent of recombination hotspot binding.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of DNA binding, recombination hotspot|upregulation of recombination hotspot binding|upregulation of DNA binding, recombination hotspot|up regulation of recombination hotspot binding|up-regulation of recombination hotspot binding|activation of DNA binding, recombination hotspot|activation of recombination hotspot binding|positive regulation of DNA binding, recombination hotspot|up regulation of DNA binding, recombination hotspot							al	2014-11-21T12:02:31Z					biological_process											owl:Class	
GO:1903642	biolink:NamedThing	regulation of recombination hotspot binding	Any process that modulates the frequency, rate or extent of recombination hotspot binding.	tmpzr1t_l9r_go_relaxed.owl	regulation of DNA binding, recombination hotspot							al	2014-11-21T12:02:22Z					biological_process											owl:Class	
GO:0043447	biolink:NamedThing	alkane biosynthetic process	The chemical reactions and pathways resulting in the formation of an alkane, any acyclic branched or unbranched hydrocarbon having the general formula CnH2n+2.	tmpzr1t_l9r_go_relaxed.owl	alkane biosynthesis|alkane anabolism|alkane synthesis|alkane formation													biological_process											owl:Class	
GO:1990671	biolink:NamedThing	vesicle fusion with Golgi medial cisterna membrane	The joining of the lipid bilayer membrane around a vesicle to the lipid bilayer membrane around the Golgi medial cisterna. This can involve anterograde or retrograde transport vesicles.	tmpzr1t_l9r_go_relaxed.owl								bhm	2015-03-02T11:31:01Z					biological_process											owl:Class	
GO:0060077	biolink:NamedThing	inhibitory synapse	A synapse in which an action potential in the presynaptic cell reduces the probability of an action potential occurring in the postsynaptic cell.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Inhibitory_postsynaptic_potential									cellular_component											owl:Class	
GO:0070648	biolink:NamedThing	formin-nucleated actin cable	An actin filament bundle that consists of short filaments organized into bundles of uniform polarity, and is nucleated by formins. In fungal cells, myosin motors transport cargo along actin cables toward sites of polarized cell growth; actin cables may play a similar role in pollen tube growth.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-05-12T02:09:57Z					cellular_component											owl:Class	
GO:0097518	biolink:NamedThing	parallel actin filament bundle	An actin filament bundle in which the filaments are tightly packed (approximately 10-20 nm apart) and oriented with the same polarity.	tmpzr1t_l9r_go_relaxed.owl								pr	2013-10-16T15:42:17Z					cellular_component											owl:Class	
GO:0110052	biolink:NamedThing	toxic metabolite repair	A cellular process that, through single- or multi-step enzymatic reactions, repairs toxic endogenous compounds, formed as by-products of primary metabolism, by converting them into useful metabolites.	tmpzr1t_l9r_go_relaxed.owl								kmv	2017-09-08T15:19:16Z					biological_process											owl:Class	
GO:0002292	biolink:NamedThing	T cell differentiation involved in immune response	The process in which an antigenically naive T cell acquires the specialized features of an effector, regulatory, or memory T cell as part of an immune response. Effector T cells include cells which provide T cell help or exhibit cytotoxicity towards other cells.	tmpzr1t_l9r_go_relaxed.owl	T cell development involved in immune response|T cell differentiation during immune response|T-cell differentiation during immune response|T lymphocyte differentiation during immune response|T-lymphocyte differentiation during immune response					Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.								biological_process											owl:Class	
GO:0072381	biolink:NamedThing	positive regulation of canonical Wnt signaling pathway involved in neural crest cell differentiation	Any process that increases the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin involved in neural crest cell differentiation. The Wnt signaling pathway is the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of Wnt receptor signaling pathway through beta-catenin involved in neural crest cell differentiation|positive regulation of canonical Wnt receptor signalling pathway involved in neural crest cell differentiation|positive regulation of canonical Wnt receptor signaling pathway involved in neural crest cell differentiation|positive regulation of canonical Wnt-activated signaling pathway involved in neural crest cell differentiation							mah	2010-11-24T03:10:15Z					biological_process											owl:Class	
GO:0072335	biolink:NamedThing	regulation of canonical Wnt signaling pathway involved in neural crest cell differentiation	Any process that modulates the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin involved in neural crest cell differentiation. The Wnt signaling pathway is the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes.	tmpzr1t_l9r_go_relaxed.owl	regulation of canonical Wnt-activated signaling pathway involved in neural crest cell differentiation|regulation of canonical Wnt receptor signalling pathway involved in neural crest cell differentiation|regulation of Wnt receptor signaling pathway through beta-catenin involved in neural crest cell differentiation|regulation of canonical Wnt receptor signaling pathway involved in neural crest cell differentiation							mah	2010-11-03T03:12:38Z					biological_process											owl:Class	
GO:1903535	biolink:NamedThing	negative regulation of lactose biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of lactose biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	down regulation of lactose biosynthesis|down-regulation of lactose biosynthesis|inhibition of lactose anabolism|downregulation of lactose anabolism|down regulation of lactose formation|downregulation of lactose formation|negative regulation of lactose anabolism|down regulation of lactose biosynthetic process|down-regulation of lactose synthesis|downregulation of lactose biosynthesis|down-regulation of lactose biosynthetic process|downregulation of lactose synthesis|negative regulation of lactose formation|down-regulation of lactose anabolism|down regulation of lactose synthesis|down-regulation of lactose formation|down regulation of lactose anabolism|inhibition of lactose formation|inhibition of lactose synthesis|downregulation of lactose biosynthetic process|inhibition of lactose biosynthesis|negative regulation of lactose synthesis|negative regulation of lactose biosynthesis|inhibition of lactose biosynthetic process							mr	2014-10-08T16:26:14Z					biological_process											owl:Class	
GO:0003158	biolink:NamedThing	endothelium development	The process whose specific outcome is the progression of an endothelium over time, from its formation to the mature structure. Endothelium refers to the layer of cells lining blood vessels, lymphatics, the heart, and serous cavities, and is derived from bone marrow or mesoderm. Corneal endothelium is a special case, derived from neural crest cells.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-10-01T12:50:57Z					biological_process											owl:Class	
GO:0045699	biolink:NamedThing	positive regulation of synergid differentiation	Any process that activates or increases the frequency, rate or extent of synergid cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	up regulation of synergid differentiation|stimulation of synergid differentiation|activation of synergid differentiation|up-regulation of synergid differentiation|positive regulation of synergid cell differentiation|upregulation of synergid differentiation													biological_process											owl:Class	
GO:1901977	biolink:NamedThing	negative regulation of cell cycle checkpoint	Any process that stops, prevents or reduces the frequency, rate or extent of cell cycle checkpoint.	tmpzr1t_l9r_go_relaxed.owl	downregulation of cell cycle checkpoint|down regulation of cell cycle checkpoint|negative regulation of G1/S transition checkpoint|inhibition of cell cycle checkpoint|negative regulation of G1/S checkpoint|down-regulation of cell cycle checkpoint					Note that this term should not be used for direct manual annotation as it should always be possible to specify the type of checkpoint (i.e mitotic spindle or DNA damage etc).		jl	2013-03-06T15:10:29Z			GO:2001048		biological_process											owl:Class	
GO:0043084	biolink:NamedThing	penile erection	The hardening, enlarging and rising of the penis which often occurs in the sexually aroused male and enables sexual intercourse. Achieved by increased inflow of blood into the vessels of erectile tissue, and decreased outflow.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Erection#Penile_erection									biological_process											owl:Class	
GO:0030860	biolink:NamedThing	regulation of polarized epithelial cell differentiation	Any process that modulates the frequency, rate or extent of polarized epithelial cell differentiation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0120072	biolink:NamedThing	positive regulation of pyloric antrum smooth muscle contraction	Any process that increases the frequency, rate or extent of any pyloric antrum smooth muscle contraction.	tmpzr1t_l9r_go_relaxed.owl								krc	2017-06-13T23:32:56Z					biological_process											owl:Class	
GO:1990778	biolink:NamedThing	protein localization to cell periphery	A process in which a protein is transported to, or maintained in, the cell periphery.	tmpzr1t_l9r_go_relaxed.owl									2015-06-18T22:37:39Z					biological_process											owl:Class	
GO:0004383	biolink:NamedThing	guanylate cyclase activity	Catalysis of the reaction: GTP = 3',5'-cyclic GMP + diphosphate.	tmpzr1t_l9r_go_relaxed.owl	receptor guanylate cyclase activity|GTP diphosphate-lyase (cyclizing; 3',5'-cyclic-GMP-forming) activity|guanyl cyclase activity|GTP diphosphate-lyase (cyclizing) activity|guanylyl cyclase activity				Reactome:R-HSA-74885|MetaCyc:GUANYLCYC-RXN|Reactome:R-HSA-392152|EC:4.6.1.2|RHEA:13665									molecular_function											owl:Class	
GO:0016849	biolink:NamedThing	phosphorus-oxygen lyase activity	Catalysis of the cleavage of a phosphorus-oxygen bond by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond.	tmpzr1t_l9r_go_relaxed.owl					EC:4.6.-.-									molecular_function											owl:Class	
GO:0055065	biolink:NamedThing	metal ion homeostasis	Any process involved in the maintenance of an internal steady state of metal ions within an organism or cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0072748	biolink:NamedThing	cellular response to tacrolimus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tacrolimus (FK506) stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to tacrolimus hydrate|cellular response to FK506							mah	2012-08-31T12:34:32Z					biological_process											owl:Class	
GO:1990972	biolink:NamedThing	multimerin complex	Glycoprotein complex of the C1q/TNF superfamily involved in cell adhesion. A homotrimer that will combine to form supramolecular Multimerin structures.	tmpzr1t_l9r_go_relaxed.owl	Elastic microfibrillar interface 4 complex|Platelet glycoprotein Ia* complex|Multimerin-2 complex|EMILIN-4 complex|p155 complex|EMILIN-3 complex|Elastic microfibrillar interface 3 complex|Multimerin-1 complex					An example of this is Multimerin-1 in human (Q13201) in PMID:9454761.		bhm	2016-06-21T14:49:42Z					cellular_component											owl:Class	
GO:0098637	biolink:NamedThing	protein complex involved in cell-matrix adhesion	Any protein complex that is capable of carrying out some part of the process of cell-matrix adhesion.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0061716	biolink:NamedThing	miRNA export from nucleus	The directed movement of a processed miRNA from the nucleus to the cytoplasm.	tmpzr1t_l9r_go_relaxed.owl								dph	2015-06-29T08:54:41Z					biological_process											owl:Class	
GO:0097064	biolink:NamedThing	ncRNA export from nucleus	The directed movement of a non-coding RNA transcript (ncRNA) from the nucleus to the cytoplasm.	tmpzr1t_l9r_go_relaxed.owl	non-coding RNA export from nucleus							pr	2011-06-08T12:34:34Z					biological_process											owl:Class	
GO:0051354	biolink:NamedThing	negative regulation of oxidoreductase activity	Any process that stops or reduces the rate of oxidoreductase activity, the catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered.	tmpzr1t_l9r_go_relaxed.owl	inhibition of oxidoreductase activity|downregulation of oxidoreductase activity|oxidoreductase inhibitor|down regulation of oxidoreductase activity|down-regulation of oxidoreductase activity													biological_process											owl:Class	
GO:1903307	biolink:NamedThing	positive regulation of regulated secretory pathway	Any process that activates or increases the frequency, rate or extent of regulated secretory pathway.	tmpzr1t_l9r_go_relaxed.owl	up regulation of regulated secretory pathway|up-regulation of regulated secretory pathway|upregulation of regulated secretory pathway|activation of regulated secretory pathway					An example of this is protein domain-specific expression of Synaptotagmin 1 in rat (P21707) in PMID:12526776 inferred from mutant phenotype.		pad	2014-08-18T10:05:10Z					biological_process											owl:Class	
GO:0045921	biolink:NamedThing	positive regulation of exocytosis	Any process that activates or increases the frequency, rate or extent of exocytosis.	tmpzr1t_l9r_go_relaxed.owl	stimulation of exocytosis|up regulation of exocytosis|activation of exocytosis|up-regulation of exocytosis|upregulation of exocytosis													biological_process											owl:Class	
GO:0004362	biolink:NamedThing	glutathione-disulfide reductase (NADPH) activity	Catalysis of the reaction: 2 glutathione + NADP+ = glutathione disulfide + NADPH + H+.	tmpzr1t_l9r_go_relaxed.owl	NADPH-glutathione reductase activity|NADPH-GSSG reductase activity|NADPH:oxidized-glutathione oxidoreductase activity|glutathione reductase activity|glutathione S-reductase activity|oxidized glutathione reduction|GSH reductase activity|glutathione:NADP+ oxidoreductase activity|glutathione-disulfide reductase activity|GSSG reductase activity|glutathione-disulphide reductase activity	glutathione-disulfide reductase activity			Reactome:R-HSA-71682|EC:1.8.1.7|MetaCyc:GLUTATHIONE-REDUCT-NADPH-RXN|Reactome:R-HSA-3323079|RHEA:11740	Note that this function was formerly EC:1.6.4.2.								molecular_function											owl:Class	
GO:0043003	biolink:NamedThing	positive regulation of Golgi to plasma membrane CFTR protein transport	Any process that activates or increases the frequency, rate or extent of transport of Cystic Fibrosis Transmembrane conductance Regulator (CFTR) protein from the Golgi to the plasma membrane.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of Golgi to plasma membrane CFTR protein transport|up regulation of Golgi to plasma membrane CFTR protein transport|stimulation of Golgi to plasma membrane CFTR protein transport|activation of Golgi to plasma membrane CFTR protein transport|upregulation of Golgi to plasma membrane CFTR protein transport													biological_process											owl:Class	
GO:0042999	biolink:NamedThing	regulation of Golgi to plasma membrane CFTR protein transport	Any process that modulates the frequency, rate or extent of transport of Cystic Fibrosis Transmembrane conductance Regulator (CFTR) protein from the Golgi to the plasma membrane.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0071302	biolink:NamedThing	cellular response to vitamin B2	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin B2 stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to riboflavin							mah	2009-12-10T04:34:52Z					biological_process											owl:Class	
GO:0014001	biolink:NamedThing	sclerenchyma cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a sclerenchyma cell. A sclerenchyma cell is a plant cell with thick lignified walls, normally dead at maturity and specialized for structural strength. Includes fiber cells, that are greatly elongated; and sclereids, that are more isodiametric. Intermediate types exist. Cells may or may not be devoid of protoplasm at maturity. Cell form and size are variable.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0050292	biolink:NamedThing	steroid 9-alpha-monooxygenase activity	Catalysis of the reaction: AH(2) + O(2) + pregna-4,9(11)-diene-3,20-dione = 9,11alpha-epoxypregn-4-ene-3,20-dione + A + H(2)O.	tmpzr1t_l9r_go_relaxed.owl	steroid 9-alpha-hydroxylase activity|steroid 9a-monooxygenase activity|steroid 9alpha-monooxygenase activity|steroid,hydrogen-donor:oxygen oxidoreductase (9-epoxidizing)|steroid 9alpha-hydroxylase activity				RHEA:19557|MetaCyc:STEROID-9-ALPHA-MONOOXYGENASE-RXN|EC:1.14.99.24|KEGG_REACTION:R04392									molecular_function											owl:Class	
GO:0072341	biolink:NamedThing	modified amino acid binding	Binding to a modified amino acid.	tmpzr1t_l9r_go_relaxed.owl	amino acid derivative binding							mah	2010-11-04T05:45:32Z					molecular_function											owl:Class	
GO:1904329	biolink:NamedThing	negative regulation of myofibroblast contraction	Any process that stops, prevents or reduces the frequency, rate or extent of myofibroblast contraction.	tmpzr1t_l9r_go_relaxed.owl	inhibition of myofibroblast contraction|negative regulation of MF contraction|downregulation of myofibroblast contraction|down-regulation of MFB contraction|inhibition of MF contraction|down-regulation of myofibroblast contraction|inhibition of MFB contraction|downregulation of MF contraction|down regulation of MF contraction|down regulation of myofibroblast contraction|down regulation of MFB contraction|down-regulation of MF contraction|negative regulation of MFB contraction|downregulation of MFB contraction							sl	2015-06-11T15:30:35Z					biological_process											owl:Class	
GO:0019566	biolink:NamedThing	arabinose metabolic process	The chemical reactions and pathways involving arabinose, arabino-pentose. L-Arabinose occurs both free, for example in the heartwood of many conifers, and in the combined state, as a constituent of plant hemicelluloses, bacterial polysaccharides etc. D-arabinose is a constituent of arabinonucleosides.	tmpzr1t_l9r_go_relaxed.owl	arabinose metabolism													biological_process											owl:Class	
GO:0045873	biolink:NamedThing	negative regulation of sevenless signaling pathway	Any process that stops, prevents, or reduces the frequency, rate or extent of the sevenless signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of sev signaling pathway|negative regulation of sevenless signalling pathway|inhibition of sevenless signaling pathway|downregulation of sevenless signaling pathway|down regulation of sevenless signaling pathway|down-regulation of sevenless signaling pathway													biological_process											owl:Class	
GO:0019262	biolink:NamedThing	N-acetylneuraminate catabolic process	The chemical reactions and pathways resulting in the breakdown of N-acetylneuraminate, the anion of 5-(acetylamino)-3,5-dideoxy-D-glycero-D-galacto-non-3-ulosonic acid.	tmpzr1t_l9r_go_relaxed.owl	N-acetylneuraminate degradation|N-acetylneuraminate breakdown|N-acetylneuraminate catabolism				MetaCyc:P441-PWY									biological_process											owl:Class	
GO:0046213	biolink:NamedThing	methyl ethyl ketone catabolic process	The chemical reactions and pathways resulting in the breakdown of methyl ethyl ketone, a clear, colorless liquid with a fragrant, mint-like odor.	tmpzr1t_l9r_go_relaxed.owl	methyl ethyl ketone breakdown|methyl ethyl ketone catabolism|methyl ethyl ketone degradation													biological_process											owl:Class	
GO:0018928	biolink:NamedThing	methyl ethyl ketone metabolic process	The chemical reactions and pathways involving methyl ethyl ketone, a clear, colorless liquid with a fragrant, mint-like odor. It is used as a solvent and in making plastics, textiles and paints.	tmpzr1t_l9r_go_relaxed.owl	2-butanone metabolism|MEK metabolism|MEK metabolic process|methyl ethyl ketone metabolism|2-butanone metabolic process				UM-BBD_pathwayID:mek									biological_process											owl:Class	
GO:0010138	biolink:NamedThing	pyrimidine ribonucleotide salvage	The pathway by which pyrimidine bases or pyrimidine ribonucleosides from pyrimidine nucleotide breakdown are converted back to pyrimidine ribonucleotides. The salvage pathway is important where there is no de novo pyrimidine nucleotide biosynthesis.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:PWY0-163									biological_process											owl:Class	
GO:0070600	biolink:NamedThing	fungal-type cell wall (1->3)-alpha-glucan biosynthetic process	The chemical reactions and pathways resulting in the formation of (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds, found in fungal-type cell walls, including those of ascospores.	tmpzr1t_l9r_go_relaxed.owl	fungal-type cell wall alpha-1,3-glucan formation|fungal-type cell wall 1,3-alpha-glucan anabolism|fungal-type cell wall 1,3-alpha-glucan formation|fungal-type cell wall alpha-1,3-glucan anabolism|fungal-type cell wall 1,3-alpha-glucan biosynthetic process|fungal-type cell wall 1,3-alpha-glucan biosynthesis|fungal-type cell wall alpha-1,3-glucan biosynthetic process|fungal-type cell wall alpha-1,3-glucan biosynthesis|fungal-type cell wall alpha-1,3-glucan synthesis|fungal-type cell wall 1,3-alpha-glucan synthesis							mah	2009-04-28T04:09:48Z					biological_process											owl:Class	
GO:0070599	biolink:NamedThing	fungal-type cell wall (1->3)-alpha-glucan metabolic process	The chemical reactions and pathways involving (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds, found in the walls of ascospores.	tmpzr1t_l9r_go_relaxed.owl	ascospore wall 1,3-alpha-glucan metabolic process|ascospore wall alpha-1,3 glucan metabolic process|ascospore wall alpha-1,3 glucan metabolism|ascospore wall 1,3-alpha-glucan metabolism							mah	2009-04-28T04:07:23Z					biological_process											owl:Class	
GO:0102704	biolink:NamedThing	GDP-Man:Man2GlcNAc2-PP-dolichol alpha-1,6-mannosyltransferase activity	Catalysis of the reaction: GDP-alpha-D-mannose(2-) + a (mannosyl)2-(N-acetylglucosaminyl)2-diphosphodolichol <=> H+ + GDP(3-) + a (mannosyl)3-(N-acetylglucosaminyl)2-diphosphodolichol.	tmpzr1t_l9r_go_relaxed.owl					RHEA:29519|EC:2.4.1.257|MetaCyc:RXN-5463									molecular_function											owl:Class	
GO:0014889	biolink:NamedThing	muscle atrophy	A process, occurring in the muscle, that is characterized by a decrease in protein content, fiber diameter, force production and fatigue resistance in response to different conditions such as starvation, aging and disuse.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Muscle_atrophy	GO:0014889 should only be used for annotation when muscle atrophy is a normal physiological process and not a disease process.								biological_process											owl:Class	
GO:0043500	biolink:NamedThing	muscle adaptation	A process in which muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. These adaptive events occur in both muscle fibers and associated structures (motoneurons and capillaries), and they involve alterations in regulatory mechanisms, contractile properties and metabolic capacities.	tmpzr1t_l9r_go_relaxed.owl	muscle plasticity													biological_process											owl:Class	
GO:0006361	biolink:NamedThing	transcription initiation from RNA polymerase I promoter	Any process involved in the assembly of the RNA polymerase I preinitiation complex (PIC) at an RNA polymerase I promoter region of a DNA template, resulting in the subsequent synthesis of RNA from that promoter. The initiation phase includes PIC assembly and the formation of the first few bonds in the RNA chain, including abortive initiation, which occurs when the first few nucleotides are repeatedly synthesized and then released. Promoter clearance, or release, is the transition between the initiation and elongation phases of transcription.	tmpzr1t_l9r_go_relaxed.owl	transcription initiation from Pol I promoter|transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript					Note that promoter clearance is represented as a separate step, not part_of either initiation or elongation.		krc	2011-08-15T03:45:49Z			GO:0001180		biological_process											owl:Class	
GO:0006352	biolink:NamedThing	DNA-templated transcription, initiation	Any process involved in the assembly of the RNA polymerase preinitiation complex (PIC) at the core promoter region of a DNA template, resulting in the subsequent synthesis of RNA from that promoter. The initiation phase includes PIC assembly and the formation of the first few bonds in the RNA chain, including abortive initiation, which occurs when the first few nucleotides are repeatedly synthesized and then released. The initiation phase ends just before and does not include promoter clearance, or release, which is the transition between the initiation and elongation phases of transcription.	tmpzr1t_l9r_go_relaxed.owl	DNA-dependent RNA polymerase complex assembly at promoter|transcription initiation factor activity|transcription initiation, DNA-dependent|initiation of DNA-dependent transcription|initiation of transcription, DNA-dependent|DNA-dependent transcription, initiation|transcription initiation from bacterial-type RNA polymerase promoter					Note that promoter clearance is represented as a separate step, not part_of either initiation or elongation.						GO:0001123		biological_process											owl:Class	
GO:0061929	biolink:NamedThing	gamma-glutamylaminecyclotransferase activity	Catalysis of the reaction: epsilon-(L-gamma-glutamyl)-L-lysine = L-lysine + 5-oxo-L-proline.	tmpzr1t_l9r_go_relaxed.owl					EC:4.3.2.8|RHEA:16961			dph	2017-08-29T14:57:39Z					molecular_function											owl:Class	
GO:0046481	biolink:NamedThing	digalactosyldiacylglycerol synthase activity	Catalysis of the reaction: 1,2-diacyl-3-beta-D-galactosyl-sn-glycerol + UDP-D-galactose = 3-[alpha-D-galactosyl-(1->6)-beta-D-galactosyl]-1,2-diacyl-sn-glycerol + H(+) + UDP.	tmpzr1t_l9r_go_relaxed.owl	UDP-galactose:MGDG galactosyltransferase activity|UDP-galactose-dependent digalactosyldiacylglycerol synthase activity|DGDG synthase activity|UDP-galactose:3-(beta-D-galactosyl)-1,2-diacyl-sn-glycerol 6-alpha-galactosyltransferase activity|DGD2|DGD1|UDP-galactose-dependent DGDG synthase activity				RHEA:10520|EC:2.4.1.241|KEGG_REACTION:R04469|Wikipedia:Digalactosyldiacylglycerol_synthase|MetaCyc:RXN-1225									molecular_function											owl:Class	
GO:0071572	biolink:NamedThing	histone H3-K56 deacetylation	The modification of histone H3 by the removal of an acetyl group from lysine at position 56 of the histone.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-01-20T04:50:03Z					biological_process											owl:Class	
GO:0070932	biolink:NamedThing	histone H3 deacetylation	The modification of histone H3 by the removal of one or more acetyl groups.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-09-16T04:50:55Z					biological_process											owl:Class	
GO:1990036	biolink:NamedThing	calcium ion import into sarcoplasmic reticulum	The directed movement of calcium ions into a sarcoplasmic reticulum.	tmpzr1t_l9r_go_relaxed.owl								tb	2013-02-07T23:22:27Z					biological_process											owl:Class	
GO:0008755	biolink:NamedThing	O antigen polymerase activity	Catalysis of the polymerization of o-antigen chains. O-antigens are tetra- and pentasaccharide repeat units of the cell walls of Gram-negative bacteria and are a component of lipopolysaccharide.	tmpzr1t_l9r_go_relaxed.owl	O-antigen polymerase activity													molecular_function											owl:Class	
GO:0034543	biolink:NamedThing	5-aminosalicylate dioxygenase activity	Catalysis of the reaction: 5-aminosalicylate + O2 = cis-4-amino-6-carboxy-2-oxo-hexa-3,5-dienoate.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0809|EC:1.13.11.-									molecular_function											owl:Class	
GO:1903520	biolink:NamedThing	negative regulation of mammary gland involution	Any process that stops, prevents or reduces the frequency, rate or extent of mammary gland involution.	tmpzr1t_l9r_go_relaxed.owl	downregulation of mammary gland involution|inhibition of mammary gland involution|down regulation of mammary gland involution|down-regulation of mammary gland involution							dph	2014-10-06T12:01:30Z					biological_process											owl:Class	
GO:0097281	biolink:NamedThing	immune complex formation	The process that gives rise to an immune complex. Immune complexes are clusters of antibodies bound to antigen, to which complement may also be fixed, and which may precipitate or remain in solution. Examples are the clumping of cells such as bacteria or red blood cells in the presence of an antibody, precipitation of a toxin after an antibody binds to it, and clumping of viral particles as a result of antibody binding to the virus.	tmpzr1t_l9r_go_relaxed.owl	antibody-mediated agglutination							pr	2012-03-26T01:35:21Z					biological_process											owl:Class	
GO:0002086	biolink:NamedThing	diaphragm contraction	A process in which force is generated within involuntary skeletal muscle tissue, resulting in a change in muscle geometry. This process occurs in the diaphragm. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The diaphragm is a striated muscle that is necessary for the process of respiratory gaseous exchange.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0003011	biolink:NamedThing	involuntary skeletal muscle contraction	A process in which force is generated within involuntary skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. Involuntary skeletal muscle is skeletal muscle that is not under conscious control.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0072238	biolink:NamedThing	metanephric long nephron development	The process whose specific outcome is the progression of a metanephric long nephron over time, from its formation to the mature structure. Long nephrons are associated with juxtamedullary glomeruli and extend into the inner medulla in the metanephros.	tmpzr1t_l9r_go_relaxed.owl	metanephric juxtamedullary nephron development							mah	2010-03-18T03:48:23Z					biological_process											owl:Class	
GO:0044320	biolink:NamedThing	cellular response to leptin stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leptin stimulus. Leptin is a hormone manufactured primarily in the adipocytes of white adipose tissue, and the level of circulating leptin is directly proportional to the total amount of fat in the body. It plays a key role in regulating energy intake and energy expenditure, including appetite and metabolism.	tmpzr1t_l9r_go_relaxed.owl								jl	2010-07-14T02:21:32Z					biological_process											owl:Class	
GO:0032870	biolink:NamedThing	cellular response to hormone stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hormone stimulus.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0090128	biolink:NamedThing	regulation of synapse maturation	Any process that modulates the extent of synapse maturation, the process that organizes a synapse so that it attains its fully functional state.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-12-07T03:00:58Z					biological_process											owl:Class	
GO:0050256	biolink:NamedThing	ribitol-5-phosphate 2-dehydrogenase activity	Catalysis of the reaction: D-ribitol 5-phosphate + NAD(P)+ = D-ribulose 5-phosphate + NAD(P)H + H+.	tmpzr1t_l9r_go_relaxed.owl	D-ribitol-5-phosphate:NAD(P)+ 2-oxidoreductase activity|dehydrogenase, ribitol 5-phosphate				EC:1.1.1.137|MetaCyc:RIBITOL-5-PHOSPHATE-2-DEHYDROGENASE-RXN									molecular_function											owl:Class	
GO:0018084	biolink:NamedThing	peptidyl-lactic acid biosynthetic process from peptidyl-serine	The modification of N-terminal peptidyl-serine to lactic acid.	tmpzr1t_l9r_go_relaxed.owl	peptidyl-lactic acid formation from peptidyl-serine|peptidyl-lactic acid anabolism from peptidyl-serine|peptidyl-lactic acid synthesis from peptidyl-serine				RESID:AA0186									biological_process											owl:Class	
GO:0019381	biolink:NamedThing	atrazine catabolic process	The chemical reactions and pathways resulting in the breakdown of atrazine, a triazine ring-containing herbicide.	tmpzr1t_l9r_go_relaxed.owl	atrazine degradation|atrazine breakdown|atrazine catabolism				MetaCyc:P141-PWY									biological_process											owl:Class	
GO:0034659	biolink:NamedThing	isopropylmalate transport	The directed movement of isopropylmalate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0046851	biolink:NamedThing	negative regulation of bone remodeling	Any process that stops, prevents, or reduces the frequency, rate or extent of bone remodeling.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of bone remodeling|down regulation of bone remodeling|inhibition of bone remodeling|downregulation of bone remodeling													biological_process											owl:Class	
GO:0046850	biolink:NamedThing	regulation of bone remodeling	Any process that modulates the frequency, rate or extent of bone remodeling, the processes of bone formation and resorption that combine to maintain skeletal integrity.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0050483	biolink:NamedThing	IMP 5'-nucleotidase activity	Catalysis of the reaction: 5'-IMP + H2O = inosine + phosphate.	tmpzr1t_l9r_go_relaxed.owl	IMP 5' nucleotidase activity|IMP-GMP specific 5'-nucleotidase activity				RHEA:27718|MetaCyc:RXN-7607									molecular_function											owl:Class	
GO:0008253	biolink:NamedThing	5'-nucleotidase activity	Catalysis of the reaction: a 5'-ribonucleotide + H2O = a ribonucleoside + phosphate.	tmpzr1t_l9r_go_relaxed.owl	snake venom 5'-nucleotidase|5'-mononucleotidase activity|5'-AMPase|AMP phosphatase|AMPase|5' nucleotidase activity|adenosine monophosphatase|uridine 5'-nucleotidase|UMPase|5'-adenylic phosphatase|thimidine monophosphate nucleotidase|5'-AMP nucleotidase|5'-ribonucleotide phosphohydrolase activity|AMP phosphohydrolase|adenosine 5'-phosphatase				Reactome:R-HSA-109387|Reactome:R-HSA-5694126|Reactome:R-HSA-109291|Reactome:R-HSA-109380|Reactome:R-HSA-109480|Reactome:R-HSA-109449|Reactome:R-HSA-109278|Reactome:R-HSA-109514|Reactome:R-HSA-109415|Reactome:R-HSA-8940074|Reactome:R-HSA-109470|Reactome:R-HSA-74248|MetaCyc:5-NUCLEOTID-RXN|Reactome:R-HSA-8940070|RHEA:12484|EC:3.1.3.5									molecular_function											owl:Class	
GO:1903503	biolink:NamedThing	ATPase inhibitor complex	A protein complex which is capable of ATPase inhibitor activity.	tmpzr1t_l9r_go_relaxed.owl						An example of this is Mago in drome (P49028) in PMID:16170325 (inferred from direct assay).		bhm	2014-09-30T13:55:37Z					cellular_component											owl:Class	
GO:0008963	biolink:NamedThing	phospho-N-acetylmuramoyl-pentapeptide-transferase activity	Catalysis of the reaction: UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-D-alanyl-D-alanine + undecaprenyl phosphate = UMP + N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-D-alanyl-D-alanine-diphosphoundecaprenol.	tmpzr1t_l9r_go_relaxed.owl	UDP-MurNAc-pentapeptide phosphotransferase activity|phosphoacetylmuramoylpentapeptide translocase activity|UDP-MurNAc-Ala-gammaDGlu-Lys-DAla-DAla:undecaprenylphosphate transferase activity|UDP-MurNAc-L-Ala-D-gamma-Glu-L-Lys-D-Ala-D-Ala:C(55)-isoprenoid alcohol transferase activity|MraY transferase activity|UDP-MurNAc-L-Ala-D-gamma-Glu-L-Lys-D-Ala-D-Ala:C55-isoprenoid alcohol transferase activity|phosphoacetylmuramoylpentapeptidetransferase activity|phospho-N-acetylmuramoyl pentapeptide translocase activity|UDP-MurNAc-Ala-gamma-DGlu-Lys-DAla-DAla:undecaprenylphosphate transferase activity|UDP-MurAc(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala):undecaprenyl-phosphate phospho-N-acetylmuramoyl-pentapeptide-transferase activity|phospho-NAc-muramoyl-pentapeptide translocase (UMP) activity|phospho-MurNAc-pentapeptide transferase activity				MetaCyc:RXN-8975|EC:2.7.8.13|RHEA:21920	Note that EC classifies all three 'UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine:undecaprenyl-phosphate transferase activity ; GO:0051992' and 'phospho-N-acetylmuramoyl-pentapeptide-transferase activity ; GO:0008963' under EC:2.7.8.13.								molecular_function											owl:Class	
GO:0102695	biolink:NamedThing	UDP-glucose:cis-zeatin 7-N-glucosyltransferase activity	Catalysis of the reaction: UDP-alpha-D-glucose + cis-zeatin <=> H+ + cis-zeatin-7-N-glucoside + UDP.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-4733									molecular_function											owl:Class	
GO:0006561	biolink:NamedThing	proline biosynthetic process	The chemical reactions and pathways resulting in the formation of proline (pyrrolidine-2-carboxylic acid), a chiral, cyclic, nonessential alpha-amino acid found in peptide linkage in proteins.	tmpzr1t_l9r_go_relaxed.owl	proline biosynthesis|proline anabolism|proline formation|proline synthesis				MetaCyc:PWY-3341|MetaCyc:PROSYN-PWY									biological_process											owl:Class	
GO:0019730	biolink:NamedThing	antimicrobial humoral response	An immune response against microbes mediated through a body fluid. Examples of this process are seen in the antimicrobial humoral response of Drosophila melanogaster and Mus musculus.	tmpzr1t_l9r_go_relaxed.owl												GO:0019735|GO:0006960		biological_process											owl:Class	
GO:0051707	biolink:NamedThing	response to other organism	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from another living organism.	tmpzr1t_l9r_go_relaxed.owl												GO:0042828|GO:0009613		biological_process											owl:Class	
GO:0036006	biolink:NamedThing	cellular response to macrophage colony-stimulating factor stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a macrophage colony-stimulating factor stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to M-CSF stimulus|cellular response to macrophage colony-stimulating factor							bf	2011-09-20T04:23:19Z					biological_process											owl:Class	
GO:0050494	biolink:NamedThing	GSI anchor biosynthetic process via N-glycyl-glycosylsphingolipidinositolethanolamine	The chemical reactions and pathways resulting in the formation of a C-terminal peptidyl-glycine ethanolamide-linked glycosylsphingolipidinositol (GSI) anchor following hydrolysis of a glycyl-peptide bond in the carboxy-terminal region of a membrane-associated protein.	tmpzr1t_l9r_go_relaxed.owl	GSI anchor synthesis via N-glycyl-glycosylsphingolipidinositolethanolamine|GSI anchor formation via N-glycyl-glycosylsphingolipidinositolethanolamine|GSI anchor anabolism via N-glycyl-glycosylsphingolipidinositolethanolamine				RESID:AA0165									biological_process											owl:Class	
GO:0016584	biolink:NamedThing	nucleosome positioning	Ordering of successions of nucleosomes into regular arrays so that nucleosomes are positioned at defined distances from one another.	tmpzr1t_l9r_go_relaxed.owl	nucleosome spacing													biological_process											owl:Class	
GO:1904237	biolink:NamedThing	positive regulation of substrate-dependent cell migration, cell attachment to substrate	Any process that activates or increases the frequency, rate or extent of substrate-dependent cell migration, cell attachment to substrate.	tmpzr1t_l9r_go_relaxed.owl	upregulation of substrate-bound cell migration, cell attachment to substrate|up-regulation of substrate-bound cell migration, cell attachment to substrate|positive regulation of substrate-bound cell migration, cell attachment to substrate|activation of substrate-bound cell migration, cell attachment to substrate|up regulation of substrate-dependent cell migration, cell attachment to substrate|upregulation of substrate-dependent cell migration, cell attachment to substrate|up-regulation of substrate-dependent cell migration, cell attachment to substrate|activation of substrate-dependent cell migration, cell attachment to substrate|up regulation of substrate-bound cell migration, cell attachment to substrate							pga	2015-05-15T13:30:11Z					biological_process											owl:Class	
GO:0044093	biolink:NamedThing	positive regulation of molecular function	Any process that activates or increases the rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding.	tmpzr1t_l9r_go_relaxed.owl								jl	2009-04-21T04:11:06Z					biological_process											owl:Class	
GO:0042932	biolink:NamedThing	chrysobactin transport	The directed movement of the siderophore chrysobactin (alpha-N-(2,3-dihydroxybenzoyl)-D-lysyl-L-serine) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1990454	biolink:NamedThing	L-type voltage-gated calcium channel complex	A type of voltage-dependent calcium channel responsible for excitation-contraction coupling of skeletal, smooth, and cardiac muscle. 'L' stands for 'long-lasting' referring to the length of activation.	tmpzr1t_l9r_go_relaxed.owl	cardiac muscle L-type voltage-gated calcium channel complex|skeletal muscle L-type voltage-gated calcium channel complex					Examples of this are CACNA1S, CACNA2D1, CACNB1, CACNG1 in rabbit (UniProt symbol P07293, P13806, P19517 and P19518) in PMID:12946355 (inferred from direct assay).		anm	2014-08-12T17:22:10Z					cellular_component											owl:Class	
GO:0045700	biolink:NamedThing	regulation of spermatid nuclear differentiation	Any process that modulates the frequency, rate or extent of spermatid nuclear differentiation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0019171	biolink:NamedThing	3-hydroxyacyl-[acyl-carrier-protein] dehydratase activity	Catalysis of the reaction: a (3R)-3-hydroxyacyl-[acyl-carrier protein] = H2O + a trans-delta2-enoyl-acyl-[acyl-carrier protein].	tmpzr1t_l9r_go_relaxed.owl	3-hydroxyacyl-ACP dehydratase activity|3-hydroxyacyl-[acyl-carrier protein] dehydratase activity				EC:4.2.1.59|MetaCyc:3-HYDROXYDECANOYL-ACP-DEHYDR-RXN|RHEA:13097									molecular_function											owl:Class	
GO:0048351	biolink:NamedThing	negative regulation of paraxial mesodermal cell fate specification	Any process that stops, prevents, or reduces the frequency, rate or extent of paraxial mesoderm cell fate specification.	tmpzr1t_l9r_go_relaxed.owl	downregulation of paraxial mesodermal cell fate specification|inhibition of paraxial mesodermal cell fate specification|down regulation of paraxial mesodermal cell fate specification|down-regulation of paraxial mesodermal cell fate specification													biological_process											owl:Class	
GO:0048349	biolink:NamedThing	regulation of paraxial mesodermal cell fate specification	Any process that modulates the frequency, rate or extent of paraxial mesoderm cell fate specification.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0005139	biolink:NamedThing	interleukin-7 receptor binding	Binding to an interleukin-7 receptor.	tmpzr1t_l9r_go_relaxed.owl	interleukin-7 receptor ligand|IL-7													molecular_function											owl:Class	
GO:0031519	biolink:NamedThing	PcG protein complex	A chromatin-associated multiprotein complex containing Polycomb Group proteins. In Drosophila, Polycomb group proteins are involved in the long-term maintenance of gene repression, and PcG protein complexes associate with Polycomb group response elements (PREs) in target genes to regulate higher-order chromatin structure.	tmpzr1t_l9r_go_relaxed.owl	Polycomb Group protein complex													cellular_component											owl:Class	
GO:0046137	biolink:NamedThing	negative regulation of vitamin metabolic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving a vitamin, one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of vitamin metabolism|down-regulation of vitamin metabolic process|down regulation of vitamin metabolic process|inhibition of vitamin metabolic process|downregulation of vitamin metabolic process													biological_process											owl:Class	
GO:0019683	biolink:NamedThing	glyceraldehyde-3-phosphate catabolic process	The chemical reactions and pathways resulting in the breakdown of glyceraldehyde-3-phosphate, an important intermediate in glycolysis.	tmpzr1t_l9r_go_relaxed.owl	glyceraldehyde-3-phosphate catabolism|glyceraldehyde-3-phosphate breakdown|glyceraldehyde 3-phosphate catabolic process|glyceraldehyde-3-phosphate degradation|glyceraldehyde 3-phosphate catabolism													biological_process											owl:Class	
GO:1901136	biolink:NamedThing	carbohydrate derivative catabolic process	The chemical reactions and pathways resulting in the breakdown of carbohydrate derivative.	tmpzr1t_l9r_go_relaxed.owl	carbohydrate derivative catabolism|carbohydrate derivative degradation|carbohydrate derivative breakdown							bf	2012-07-12T04:05:31Z					biological_process											owl:Class	
GO:0106274	biolink:NamedThing	NAD+-protein-arginine ADP-ribosyltransferase activity	Catalysis of the reaction: NAD+ + L-arginine = nicotinamide + N2-(ADP-D-ribosyl)-L-arginine.	tmpzr1t_l9r_go_relaxed.owl					EC:2.4.2.31|RHEA:19149			hjd	2020-07-02T01:37:02Z					molecular_function											owl:Class	
GO:0003956	biolink:NamedThing	NAD(P)+-protein-arginine ADP-ribosyltransferase activity	Catalysis of the reaction: NAD(P)+ + L-arginine = nicotinamide + N2-(ADP-D-ribosyl)-L-arginine.	tmpzr1t_l9r_go_relaxed.owl	NAD(P)(+)--arginine ADP-ribosyltransferase activity|mono(ADP-ribosyl)transferase activity|mono(ADPribosyl)transferase activity|NAD(+):L-arginine ADP-D-ribosyltransferase activity|peptidyl-arginine ADP-ribosylation activity|NAD(P)+:protein-L-arginine ADP-D-ribosyltransferase activity|ADP-ribosyltransferase activity|protein-arginine ADP-ribosyltransferase activity|NAD(P)+-arginine ADP-ribosyltransferase activity|NAD+:L-arginine ADP-D-ribosyltransferase activity|NAD(P)-arginine ADP-ribosyltransferase activity|NAD(P)+:L-arginine ADP-D-ribosyltransferase activity				EC:2.4.2.31|Reactome:R-HSA-1972385|MetaCyc:2.4.2.31-RXN									molecular_function											owl:Class	
GO:1902135	biolink:NamedThing	(+)-secoisolariciresinol biosynthetic process	The chemical reactions and pathways resulting in the formation of (+)-secoisolariciresinol.	tmpzr1t_l9r_go_relaxed.owl	(+)-secoisolariciresinol synthesis|(+)-secoisolariciresinol biosynthesis|(+)-secoisolariciresinol anabolism|(+)-secoisolariciresinol formation							ms	2013-05-21T08:50:14Z					biological_process											owl:Class	
GO:0042975	biolink:NamedThing	peroxisome proliferator activated receptor binding	Binding to a peroxisome proliferator activated receptor, alpha, beta or gamma.	tmpzr1t_l9r_go_relaxed.owl	PPAR binding													molecular_function											owl:Class	
GO:0018255	biolink:NamedThing	peptide cross-linking via S-glycyl-L-cysteine	The formation of S-(peptidyl-glycyl)-peptidyl-cysteine cross-links by the formation of a thiolester between cysteine and the carboxy-terminal glycine of ubiquitin and other proteins.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0206									biological_process											owl:Class	
GO:0035493	biolink:NamedThing	SNARE complex assembly	The aggregation, arrangement and bonding together of a set of components to form a SNARE complex, a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers.	tmpzr1t_l9r_go_relaxed.owl								bf	2010-04-26T02:50:52Z					biological_process											owl:Class	
GO:0061932	biolink:NamedThing	negative regulation of erythrocyte enucleation	Any process that decreases the frequency, rate or extent of erythrocyte enucleation.	tmpzr1t_l9r_go_relaxed.owl								dph	2017-09-05T13:00:15Z					biological_process											owl:Class	
GO:0047041	biolink:NamedThing	(S)-carnitine 3-dehydrogenase activity	Catalysis of the reaction: (S)-carnitine + NAD(+) = 3-dehydrocarnitine + H(+) + NADH.	tmpzr1t_l9r_go_relaxed.owl	D-carnitine dehydrogenase activity|(S)-carnitine:NAD+ oxidoreductase activity				KEGG_REACTION:R01921|EC:1.1.1.254|MetaCyc:1.1.1.254-RXN|RHEA:11556									molecular_function											owl:Class	
GO:1900811	biolink:NamedThing	helvolic acid catabolic process	The chemical reactions and pathways resulting in the breakdown of helvolic acid.	tmpzr1t_l9r_go_relaxed.owl	Fumigacin catabolic process|Fumigacin degradation|Fumigacin breakdown|helvolic acid breakdown|helvolic acid degradation|helvolic acid catabolism|Fumigacin catabolism							di	2012-06-04T10:02:51Z					biological_process											owl:Class	
GO:0051567	biolink:NamedThing	histone H3-K9 methylation	The modification of histone H3 by addition of one or more methyl groups to lysine at position 9 of the histone.	tmpzr1t_l9r_go_relaxed.owl	histone H3 K9 methylation|histone H3K9me|histone lysine H3 K9 methylation													biological_process											owl:Class	
GO:0061647	biolink:NamedThing	histone H3-K9 modification	The modification of histone H3 at a lysine in position 9 of the histone.	tmpzr1t_l9r_go_relaxed.owl								dph	2014-10-02T15:07:42Z					biological_process											owl:Class	
GO:0004748	biolink:NamedThing	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor	Catalysis of the reaction: 2'-deoxyribonucleoside diphosphate + thioredoxin disulfide + H2O = ribonucleoside diphosphate + thioredoxin. Thioredoxin disulfide is the oxidized form of thioredoxin.	tmpzr1t_l9r_go_relaxed.owl	2'-deoxyribonucleoside-diphosphate:thioredoxin-disulfide 2'-oxidoreductase activity|2'-deoxyribonucleoside-diphosphate:oxidized-thioredoxin 2'-oxidoreductase activity				EC:1.17.4.1|Reactome:R-HSA-111751|MetaCyc:RIBONUCLEOSIDE-DIP-REDUCTI-RXN|Reactome:R-HSA-111804|RHEA:23252	When thioredoxin is substituted for glutaredoxin in the reaction, annotate instead to 'ribonucleoside-diphosphate reductase, glutaredoxin disulfide as acceptor ; GO:0036175'.						GO:0016959|GO:0016960|GO:0016961		molecular_function											owl:Class	
GO:0061731	biolink:NamedThing	ribonucleoside-diphosphate reductase activity	Catalysis of the formation of 2'-deoxyribonucleoside diphosphate from ribonucleoside diphosphate, using either thioredoxin disulfide or glutaredoxin disulfide as an acceptor.	tmpzr1t_l9r_go_relaxed.owl	aerobic non-heme iron-dependent ribonucleotide reductase activity|class II ribonucleoside-diphosphate reductase activity|class II ribonucleotide reductase activity|ribonucleotide reductase activity|ribonucleoside 5'-diphosphate reductase activity|class I ribonucleotide reductase activity|class III ribonucleotide reductase activity|nucleoside diphosphate reductase activity|ribonucleotide diphosphate reductase activity|adenosylcobalamin-dependent ribonucleotide reductase activity|purine/pyrimidine nucleoside diphosphate reduction|anaerobic iron-sulfur-dependent ribonucleotide reductase activity|RNR							dph	2015-08-24T07:25:59Z					molecular_function											owl:Class	
GO:2000732	biolink:NamedThing	positive regulation of termination of RNA polymerase I transcription	Any process that activates or increases the frequency, rate or extent of termination of RNA polymerase I transcription.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of transcription termination from RNA polymerase I promoter|positive regulation of transcription termination from Pol I promoter|positive regulation of RNA polymerase I transcription termination							dph	2011-06-10T08:43:48Z					biological_process											owl:Class	
GO:0047423	biolink:NamedThing	N-methylhydantoinase (ATP-hydrolyzing) activity	Catalysis of the reaction: N-methylhydantoin + ATP + 2 H(2)O = N-carbamoylsarcosine + ADP + 3 H(+) + phosphate.	tmpzr1t_l9r_go_relaxed.owl	N-methylhydantoin amidohydrolase activity|N-methylhydantoinase activity|N-methylhydantoin hydrolase activity|methylhydantoin amidase activity|N-methylhydantoinase (ATP-hydrolysing)|N-methylimidazolidine-2,4-dione amidohydrolase (ATP-hydrolysing)				EC:3.5.2.14|MetaCyc:3.5.2.14-RXN|RHEA:11720|Wikipedia:N-methylhydantoinase_(ATP-hydrolysing)|KEGG_REACTION:R03187									molecular_function											owl:Class	
GO:2000093	biolink:NamedThing	regulation of mesonephric nephron tubule epithelial cell differentiation	Any process that modulates the frequency, rate or extent of mesonephric nephron tubule epithelial cell differentiation.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-09-03T06:12:25Z					biological_process											owl:Class	
GO:0072182	biolink:NamedThing	regulation of nephron tubule epithelial cell differentiation	Any process that modulates the frequency, rate or extent of nephron tubule epithelial cell differentiation.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-02-26T02:45:09Z					biological_process											owl:Class	
GO:0033867	biolink:NamedThing	Fas-activated serine/threonine kinase activity	Catalysis of the reaction: ATP + Fas-activated serine/threonine protein = ADP + Fas-activated serine/threonine phosphoprotein.	tmpzr1t_l9r_go_relaxed.owl	ATP:Fas-activated serine/threonine protein phosphotransferase activity|FASTK|FAST|STK10				MetaCyc:2.7.11.8-RXN|EC:2.7.11.8									molecular_function											owl:Class	
GO:0140020	biolink:NamedThing	DNA methyltransferase complex	A protein complex that possesses DNA methyltransferase activity.	tmpzr1t_l9r_go_relaxed.owl								pg	2017-04-06T19:12:09Z					cellular_component											owl:Class	
GO:0034708	biolink:NamedThing	methyltransferase complex	A protein complex that possesses methyltransferase activity.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0018335	biolink:NamedThing	protein succinylation	The modification of a protein by the addition of a succinyl group (CO-CH2-CH2-CO) to an amino acid residue.	tmpzr1t_l9r_go_relaxed.owl	protein amino acid succinylation													biological_process											owl:Class	
GO:0001101	biolink:NamedThing	response to acid chemical	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by the chemical structure of the anion portion of a dissociated acid (rather than the acid acting as a proton donor). The acid chemical may be in gaseous, liquid or solid form.	tmpzr1t_l9r_go_relaxed.owl	response to acid|response to oxoanion|response to acid anion					This term should be used to describe a response to a specific acid as a chemical. E.g., if an organism were responding to glutamate, then the response would be glutamate-specific; the organism is actually responding to the chemical structure of the anion portion of the dissociated acid. Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. If annotating experiments where an acid is playing a role as a proton donor, please annotate to GO:0010447 'response to acidic pH' instead.								biological_process											owl:Class	
GO:0032093	biolink:NamedThing	SAM domain binding	Binding to a SAM (Sterile Alpha Motif) domain, which is a 70-amino acid protein sequence that participates in protein-protein, protein-lipid, and protein-RNA interactions and is conserved from lower to higher eukaryotes.	tmpzr1t_l9r_go_relaxed.owl	Sterile Alpha Motif domain binding													molecular_function											owl:Class	
GO:0072111	biolink:NamedThing	cell proliferation involved in kidney development	The multiplication or reproduction of cells, resulting in the expansion of the population in the kidney.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-02-22T10:48:45Z					biological_process											owl:Class	
GO:0003389	biolink:NamedThing	retrograde extension	The progression of a neuronal projection over time by the attachment of a part of the cell to an anchor and the subsequent migration of the cell body away from the anchor point.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-12-09T09:22:03Z					biological_process											owl:Class	
GO:0031175	biolink:NamedThing	neuron projection development	The process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites).	tmpzr1t_l9r_go_relaxed.owl	neurite development|neurite formation|neurite growth|neurite outgrowth|neurite biosynthesis													biological_process											owl:Class	
GO:0060330	biolink:NamedThing	regulation of response to interferon-gamma	Any process that modulates the rate, frequency or extent of a response to interferon-gamma. Response to interferon gamma is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-gamma stimulus.	tmpzr1t_l9r_go_relaxed.owl	regulation of response to type II interferon|regulation of response to gamma-interferon|regulation of response to immune interferon|regulation of response to type II IFN													biological_process											owl:Class	
GO:0098722	biolink:NamedThing	asymmetric stem cell division	Division of a stem cell during which it retains its identity and buds off a daughter cell with a new identity.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0017145	biolink:NamedThing	stem cell division	The self-renewing division of a stem cell. A stem cell is an undifferentiated cell, in the embryo or adult, that can undergo unlimited division and give rise to one or several different cell types.	tmpzr1t_l9r_go_relaxed.owl	stem cell renewal													biological_process											owl:Class	
GO:0103105	biolink:NamedThing	2-oxo-6-methylthiohexanoate aminotransferase activity	Catalysis of the reaction: 2-oxo-6-methylthiohexanoate + a standard alpha amino acid <=> dihomomethionine + a 2-oxo carboxylate.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXNQT-4345									molecular_function											owl:Class	
GO:0090379	biolink:NamedThing	secondary cell wall biogenesis involved in seed trichome differentiation	A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of inextensible cellulose- and pectin-containing cell walls that are formed between the plasma membrane and primary cell wall of seed trichomes after cell expansion is complete.	tmpzr1t_l9r_go_relaxed.owl	secondary cell wall biosynthesis involved in seed trichome differentiation|seed trichome secondary wall biosynthesis					The processes involved in the massive amount of secondary wall cellulose synthesis in seed trichomes continue to 30 DPA in Gossypium spp.		tb	2010-09-15T02:24:34Z					biological_process											owl:Class	
GO:0047909	biolink:NamedThing	galactolipid O-acyltransferase activity	Catalysis of the reaction: 2 mono-beta-D-galactosyldiacylglycerol = acylmono-beta-D-galactosyl-diacylglycerol + mono-beta-D-galactosylacylglycerol.	tmpzr1t_l9r_go_relaxed.owl	galactolipid:galactolipid acyltransferase activity|mono-beta-D-galactosyldiacylglycerol:mono-beta-D-galactosyldiacylglycerol acyltransferase activity				MetaCyc:GALACTOLIPID-O-ACYLTRANSFERASE-RXN|EC:2.3.1.134									molecular_function											owl:Class	
GO:0047740	biolink:NamedThing	cephalosporin-C transaminase activity	Catalysis of the reaction: (7R)-7-(5-carboxylato-5-oxopentanamido)deacetylcephalosporanate + D-glutamate = 2-oxoglutarate + cephalosporin C.	tmpzr1t_l9r_go_relaxed.owl	cephalosporin C aminotransferase activity|cephalosporin-C:2-oxoglutarate aminotransferase activity|L-alanine:cephalosporin-C aminotransferase activity				KEGG_REACTION:R03063|EC:2.6.1.74|RHEA:14553|MetaCyc:CEPHALOSPORIN-C-TRANSAMINASE-RXN									molecular_function											owl:Class	
GO:1905702	biolink:NamedThing	regulation of inhibitory synapse assembly	Any process that modulates the frequency, rate or extent of inhibitory synapse assembly.	tmpzr1t_l9r_go_relaxed.owl	regulation of inhibitory synapse formation							tb	2016-11-16T18:55:32Z					biological_process											owl:Class	
GO:0006998	biolink:NamedThing	nuclear envelope organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear envelope.	tmpzr1t_l9r_go_relaxed.owl	nuclear envelope organisation|nuclear envelope organization and biogenesis													biological_process											owl:Class	
GO:0002290	biolink:NamedThing	gamma-delta T cell activation involved in immune response	The change in morphology and behavior of a gamma-delta T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific, leading to the initiation or perpetuation of an immune response.	tmpzr1t_l9r_go_relaxed.owl	gamma-delta T cell activation during immune response|gamma-delta T-cell activation during immune response|gamma-delta T lymphocyte activation during immune response|gamma-delta T-lymphocyte activation during immune response													biological_process											owl:Class	
GO:0003191	biolink:NamedThing	coronary sinus valve formation	The developmental process pertaining to the initial formation of the coronary sinus valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-10-08T01:09:04Z					biological_process											owl:Class	
GO:0003188	biolink:NamedThing	heart valve formation	The developmental process pertaining to the initial formation of a heart valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-10-08T12:20:15Z					biological_process											owl:Class	
GO:1902408	biolink:NamedThing	mitotic cytokinesis, site selection	Any cytokinesis, site selection that is involved in mitotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl	site selection involved in cytokinesis involved in mitotic cell cycle|site selection involved in cell cycle cytokinesis involved in mitotic cell cycle							jl	2013-09-12T12:29:13Z					biological_process											owl:Class	
GO:0007105	biolink:NamedThing	cytokinesis, site selection	The process of marking the place where cytokinesis will occur.	tmpzr1t_l9r_go_relaxed.owl	site selection involved in cell cycle cytokinesis|site selection involved in cytokinesis											GO:0010687		biological_process											owl:Class	
GO:2000605	biolink:NamedThing	positive regulation of secondary growth	Any process that activates or increases the frequency, rate or extent of secondary growth.	tmpzr1t_l9r_go_relaxed.owl								tb	2011-04-15T10:30:49Z					biological_process											owl:Class	
GO:0045927	biolink:NamedThing	positive regulation of growth	Any process that activates or increases the rate or extent of growth, the increase in size or mass of all or part of an organism.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of growth|upregulation of growth|up regulation of growth|stimulation of growth|activation of growth													biological_process											owl:Class	
GO:0031549	biolink:NamedThing	negative regulation of brain-derived neurotrophic factor receptor signaling pathway	Any process that stops, prevents, or reduces the frequency, rate or extent of signaling via the brain-derived neurotrophic factor receptor signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	inhibition of brain-derived neurotrophic factor receptor signaling pathway|down regulation of brain-derived neurotrophic factor receptor signaling pathway|negative regulation of BDNF receptor signaling pathway|negative regulation of brain-derived neurotrophic factor receptor signalling pathway|negative regulation of BDNF receptor signalling pathway|down-regulation of brain-derived neurotrophic factor receptor signaling pathway|downregulation of brain-derived neurotrophic factor receptor signaling pathway													biological_process											owl:Class	
GO:0045707	biolink:NamedThing	regulation of adult salivary gland boundary specification	Any process that modulates the frequency, rate or extent of salivary gland determination in an adult organism.	tmpzr1t_l9r_go_relaxed.owl	regulation of adult salivary gland determination													biological_process											owl:Class	
GO:0061071	biolink:NamedThing	urethra epithelium development	The progression of the urethra epithelium over time from its initial formation to the mature structure. The urethra is a renal system organ that carries urine from the bladder to outside the body. The epithelium is the tubular, planar layer of cells through which the urine passes.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-03-12T08:36:53Z					biological_process											owl:Class	
GO:0034283	biolink:NamedThing	syn-stemod-13(17)-ene synthase activity	Catalysis of the reaction: 9-alpha-copalyl diphosphate = stemod-13(17)-ene + diphosphate.	tmpzr1t_l9r_go_relaxed.owl	exo-stemodene synthase activity|9alpha-copalyl-diphosphate diphosphate-lyase [stemod-13(17)-ene-forming] activity|stemodene synthase activity|syn-stemodene synthase activity|stemod-13(17)-ene synthase activity				MetaCyc:RXN-9291|KEGG_REACTION:R09116|EC:4.2.3.34|RHEA:25556									molecular_function											owl:Class	
GO:0048515	biolink:NamedThing	spermatid differentiation	The process whose specific outcome is the progression of a spermatid over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.	tmpzr1t_l9r_go_relaxed.owl	spermatid cell differentiation													biological_process											owl:Class	
GO:1902705	biolink:NamedThing	hexose catabolic process to butyrate	The chemical reactions and pathways resulting in the breakdown of hexose to butyrate.	tmpzr1t_l9r_go_relaxed.owl	hexose degradation to butyrate|acidogenesis|hexose breakdown to butyrate|hexose catabolism to butyrate							tb	2014-02-19T18:43:32Z			GO:1990287		biological_process											owl:Class	
GO:0098607	biolink:NamedThing	methylselenocysteine deselenhydrase activity	Catalysis of the reaction: Se-Methyl-L-selenocysteine + H2O => pyruvic acid + NH3 + Methaneselenol.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-2408539			dos	2014-04-16T11:24:12Z					molecular_function											owl:Class	
GO:2000493	biolink:NamedThing	negative regulation of interleukin-18-mediated signaling pathway	Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-18-mediated signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of interleukin-18-mediated signalling pathway							pr	2011-03-16T02:00:12Z					biological_process											owl:Class	
GO:1901297	biolink:NamedThing	positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment	Any process that activates or increases the frequency, rate or extent of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment.	tmpzr1t_l9r_go_relaxed.owl	activation of canonical Wnt receptor signalling pathway involved in cardiac muscle cell fate commitment|positive regulation of canonical Wnt-activated signaling pathway involved in cardiac muscle cell fate commitment|positive regulation of canonical Wnt receptor signalling pathway involved in cardiac muscle cell fate commitment|activation of canonical Wnt receptor signaling pathway involved in cardiac muscle cell fate commitment|up regulation of canonical Wnt receptor signalling pathway involved in cardiac muscle cell fate commitment|up-regulation of canonical Wnt receptor signalling pathway involved in cardiac muscle cell fate commitment|up regulation of canonical Wnt receptor signaling pathway involved in cardiac muscle cell fate commitment|positive regulation of canonical Wnt receptor signaling pathway involved in cardiac muscle cell fate commitment|up-regulation of canonical Wnt receptor signaling pathway involved in cardiac muscle cell fate commitment|upregulation of canonical Wnt receptor signalling pathway involved in cardiac muscle cell fate commitment|upregulation of canonical Wnt receptor signaling pathway involved in cardiac muscle cell fate commitment							vk	2012-08-21T09:06:59Z					biological_process											owl:Class	
GO:1905068	biolink:NamedThing	positive regulation of canonical Wnt signaling pathway involved in heart development	Any process that activates or increases the frequency, rate or extent of canonical Wnt signaling pathway involved in heart development.	tmpzr1t_l9r_go_relaxed.owl	activation of canonical Wnt-activated signaling pathway involved in heart development|upregulation of canonical Wnt-activated signaling pathway involved in heart development|up-regulation of canonical Wnt receptor signaling pathway involved in heart development|up-regulation of canonical Wnt receptor signalling pathway involved in heart development|up regulation of canonical Wnt receptor signaling pathway involved in heart development|upregulation of canonical Wnt receptor signalling pathway involved in heart development|up regulation of canonical Wnt-activated signaling pathway involved in heart development|up-regulation of canonical Wnt signaling pathway involved in heart development|upregulation of canonical Wnt signaling pathway involved in heart development|upregulation of canonical Wnt receptor signaling pathway involved in heart development|up-regulation of canonical Wnt-activated signaling pathway involved in heart development|positive regulation of canonical Wnt receptor signaling pathway involved in heart development|activation of canonical Wnt receptor signaling pathway involved in heart development|up regulation of canonical Wnt signaling pathway involved in heart development|positive regulation of canonical Wnt receptor signalling pathway involved in heart development|activation of canonical Wnt signaling pathway involved in heart development|activation of canonical Wnt receptor signalling pathway involved in heart development|up regulation of canonical Wnt receptor signalling pathway involved in heart development|positive regulation of canonical Wnt-activated signaling pathway involved in heart development							bc	2016-03-21T12:47:15Z					biological_process											owl:Class	
GO:0009788	biolink:NamedThing	negative regulation of abscisic acid-activated signaling pathway	Any process that stops, prevents, or reduces the frequency, rate or extent of abscisic acid (ABA) signaling.	tmpzr1t_l9r_go_relaxed.owl	down regulation of abscisic acid mediated signaling|downregulation of abscisic acid mediated signaling|negative regulation of abscisic acid mediated signalling|inhibition of abscisic acid mediated signaling|down-regulation of abscisic acid mediated signaling|negative regulation of abscisic acid mediated signaling pathway													biological_process											owl:Class	
GO:1905958	biolink:NamedThing	negative regulation of cellular response to alcohol	Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to alcohol.	tmpzr1t_l9r_go_relaxed.owl	downregulation of cellular response to alcohol|inhibition of cellular response to alcohol|down regulation of cellular response to alcohol|down-regulation of cellular response to alcohol							hbye	2017-02-22T12:03:08Z					biological_process											owl:Class	
GO:0008086	biolink:NamedThing	light-activated voltage-gated calcium channel activity	Enables the transmembrane transfer of a calcium ion by a voltage-gated channel that is activated in response to light. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.	tmpzr1t_l9r_go_relaxed.owl	light-activated voltage gated calcium channel activity|light-activated voltage-dependent calcium channel activity													molecular_function											owl:Class	
GO:0010461	biolink:NamedThing	light-activated ion channel activity	Enables the transmembrane transfer of an ion by a channel that opens in response to a light stimulus.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1990440	biolink:NamedThing	positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress	Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of an endoplasmic reticulum stress.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress|ER stress-induced upregulation of transcription|up-regulation of transcription induced by ER stress|activation of transcription from RNA polymerase II promoter in response to ER stress|upregulation of Pol II transcription induced by ER stress|stimulation of transcription from RNA polymerase II promoter in response to ER stress|upregulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress							bf	2014-07-31T12:56:54Z					biological_process											owl:Class	
GO:0031449	biolink:NamedThing	regulation of slow-twitch skeletal muscle fiber contraction	Any process that modulates the frequency, rate or extent of slow-twitch skeletal muscle contraction.	tmpzr1t_l9r_go_relaxed.owl	regulation of slow-twitch skeletal muscle contraction													biological_process											owl:Class	
GO:1904684	biolink:NamedThing	negative regulation of metalloendopeptidase activity	Any process that stops, prevents or reduces the frequency, rate or extent of metalloendopeptidase activity.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of metalloendoprotease activity|downregulation of metalloendoprotease activity|down regulation of metalloendoproteinase activity|down-regulation of metalloendopeptidase activity|inhibition of metalloendoprotease activity|negative regulation of metalloendoproteinase activity|downregulation of metalloendoproteinase activity|inhibition of metalloendoproteinase activity|downregulation of metalloendopeptidase activity|down regulation of metalloendopeptidase activity|negative regulation of metalloendoprotease activity|down regulation of metalloendoprotease activity|down-regulation of metalloendoproteinase activity|inhibition of metalloendopeptidase activity							rph	2015-09-24T11:18:21Z					biological_process											owl:Class	
GO:1905939	biolink:NamedThing	regulation of gonad development	Any process that modulates the frequency, rate or extent of gonad development.	tmpzr1t_l9r_go_relaxed.owl	regulation of gonadogenesis							hbye	2017-02-09T17:01:50Z					biological_process											owl:Class	
GO:0032570	biolink:NamedThing	response to progesterone	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a progesterone stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to progesterone stimulus													biological_process											owl:Class	
GO:0048545	biolink:NamedThing	response to steroid hormone	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a steroid hormone stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to steroid hormone stimulus													biological_process											owl:Class	
GO:0102839	biolink:NamedThing	1-18:2-2-16:2-monogalactosyldiacylglycerol desaturase activity	Catalysis of the reaction: 1-18:2-2-16:2-monogalactosyldiacylglycerol + O2 + a reduced electron acceptor <=> 1-18:3-2-16:2-monogalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor.	tmpzr1t_l9r_go_relaxed.owl					EC:1.14.19.35|MetaCyc:RXN-8299									molecular_function											owl:Class	
GO:0009207	biolink:NamedThing	purine ribonucleoside triphosphate catabolic process	The chemical reactions and pathways resulting in the breakdown of purine ribonucleoside triphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with triphosphate on the sugar.	tmpzr1t_l9r_go_relaxed.owl	purine ribonucleoside triphosphate degradation|purine ribonucleoside triphosphate catabolism|purine ribonucleoside triphosphate breakdown													biological_process											owl:Class	
GO:0043332	biolink:NamedThing	mating projection tip	The apex of the mating projection in unicellular fungi exposed to mating pheromone; site of polarized growth.	tmpzr1t_l9r_go_relaxed.owl	shmoo tip|conjugation tube tip													cellular_component											owl:Class	
GO:0051286	biolink:NamedThing	cell tip	The region at the end of the longest axis of a cylindrical or elongated cell.	tmpzr1t_l9r_go_relaxed.owl	cell end					Note that this term differs from 'cell pole ; GO:0060187' in that it is applicable to the thin ends of elongated cells, such as the ends of axons or dendrites.								cellular_component											owl:Class	
GO:0036423	biolink:NamedThing	hexaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) activity	Catalysis of the reaction: (2E,6E)-farnesyl diphosphate + 3 isopentenyl diphosphate = 3 diphosphate + all-trans-hexaprenyl diphosphate.	tmpzr1t_l9r_go_relaxed.owl	hexaprenyl diphosphate synthase activity|hexaprenyl pyrophosphate synthetase activity				MetaCyc:TRANS-PENTAPRENYLTRANSFERASE-RXN|KEGG_REACTION:R09245|EC:2.5.1.83|RHEA:27559			bf	2013-09-16T12:22:10Z					molecular_function											owl:Class	
GO:0070435	biolink:NamedThing	Shc-EGFR complex	A protein complex that contains the epidermal growth factor receptor (EGFR) and the adaptor protein Shc, and is involved in linking EGFR activation to the p21-Ras pathway.	tmpzr1t_l9r_go_relaxed.owl	Shc-Egfr complex, EGF stimulated													cellular_component											owl:Class	
GO:0015412	biolink:NamedThing	ABC-type molybdate transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + molybdate(out) = ADP + phosphate + molybdate(in).	tmpzr1t_l9r_go_relaxed.owl	molybdate transporting ATPase activity|molybdate porter activity|molybdate ABC transporter|molybdate transmembrane-transporting ATPase activity|molybdate-transporting ATPase activity|ATPase-coupled molybdate transmembrane transporter activity				EC:7.3.2.5|RHEA:22020|MetaCyc:3.6.3.29-RXN									molecular_function											owl:Class	
GO:0015098	biolink:NamedThing	molybdate ion transmembrane transporter activity	Enables the transfer of molybdate (MoO4 2-) ions from one side of a membrane to the other. Molybdate is the bivalent anion derived from molybdic acid.	tmpzr1t_l9r_go_relaxed.owl	molybdate transporter activity													molecular_function											owl:Class	
GO:0035562	biolink:NamedThing	negative regulation of chromatin binding	Any process that stops or reduces the frequency, rate or extent of chromatin binding. Chromatin binding is the selective interaction with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.	tmpzr1t_l9r_go_relaxed.owl								bf	2010-05-19T10:29:06Z					biological_process											owl:Class	
GO:1904173	biolink:NamedThing	regulation of histone demethylase activity (H3-K4 specific)	Any process that modulates the frequency, rate or extent of histone demethylase activity (H3-K4 specific).	tmpzr1t_l9r_go_relaxed.owl								dph	2015-04-24T19:29:32Z					biological_process											owl:Class	
GO:0045805	biolink:NamedThing	positive regulation of eclosion	Any process that activates or increases the frequency, rate or extent of eclosion.	tmpzr1t_l9r_go_relaxed.owl	stimulation of eclosion|up regulation of eclosion|upregulation of eclosion|up-regulation of eclosion|activation of eclosion													biological_process											owl:Class	
GO:0038015	biolink:NamedThing	positive regulation of insulin receptor signaling pathway by insulin receptor internalization	Any process in which internalization of an insulin receptor activates or increases the frequency, rate or extent of the insulin receptor signaling pathway. Endocytosis of activated receptors can concentrate receptors within endosomes and allow the insulin receptor to phosphorylate substrates that are spatially distinct from those accessible at the plasma membrane.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of insulin receptor signalling pathway by insulin receptor internalization							bf	2011-06-23T04:20:11Z					biological_process											owl:Class	
GO:0038016	biolink:NamedThing	insulin receptor internalization	A receptor-mediated endocytosis process that results in the movement of an insulin receptor from the plasma membrane to the inside of the cell.	tmpzr1t_l9r_go_relaxed.owl	insulin receptor endocytosis							bf	2011-06-23T04:24:52Z					biological_process											owl:Class	
GO:0045156	biolink:NamedThing	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity	Enables the directed movement of electrons within the cyclic electron transport pathway of photosynthesis.	tmpzr1t_l9r_go_relaxed.owl	cytochrome|cytochrome bc1 complex													molecular_function											owl:Class	
GO:0033184	biolink:NamedThing	positive regulation of histone ubiquitination	Any process that activates or increases the frequency, rate or extent of the addition of a ubiquitin group to a histone protein.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0031398	biolink:NamedThing	positive regulation of protein ubiquitination	Any process that activates or increases the frequency, rate or extent of the addition of ubiquitin groups to a protein.	tmpzr1t_l9r_go_relaxed.owl	up regulation of protein ubiquitination|upregulation of protein ubiquitination|activation of protein ubiquitination|stimulation of protein ubiquitination|up-regulation of protein ubiquitination													biological_process											owl:Class	
GO:0035491	biolink:NamedThing	positive regulation of leukotriene production involved in inflammatory response	Any process that increases the rate, frequency or extent of the synthesis or release of any leukotriene following a stimulus as part of an inflammatory response.	tmpzr1t_l9r_go_relaxed.owl								bf	2010-04-26T10:50:14Z					biological_process											owl:Class	
GO:0004043	biolink:NamedThing	L-aminoadipate-semialdehyde dehydrogenase activity	Catalysis of the reaction: L-2-aminoadipate 6-semialdehyde + NADP+ + H2O = L-2-aminoadipate + NADPH + H+.	tmpzr1t_l9r_go_relaxed.owl	L-alpha-aminoadipate delta-semialdehyde oxidoreductase activity|aminoadipate semialdehyde dehydrogenase activity|AAR|alpha-aminoadipate reductase activity|L-2-aminoadipate-6-semialdehyde:NAD(P)+ 6-oxidoreductase|alpha-aminoadipate-semialdehyde dehydrogenase activity|2-aminoadipate semialdehyde dehydrogenase activity|L-alpha-aminoadipate delta-semialdehyde:NAD oxidoreductase activity|aminoadipate-semialdehyde dehydrogenase activity|2-aminoadipic semialdehyde dehydrogenase activity|L-alpha-aminoadipate delta-semialdehyde:nicotinamide adenine dinucleotide oxidoreductase activity				MetaCyc:1.2.1.31-RXN|EC:1.2.1.31|RHEA:12308|Reactome:R-HSA-70941									molecular_function											owl:Class	
GO:0140532	biolink:NamedThing	negative regulation of osmosensory signaling MAPK cascade	Any process that stops, prevents or reduces the frequency, rate or extent of osmosensory signaling MAPK cascade.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/20162						pg	2020-10-20T15:39:24Z					biological_process											owl:Class	
GO:2000953	biolink:NamedThing	positive regulation of xyloglucan catabolic process	Any process that activates or increases the frequency, rate or extent of xyloglucan catabolic process.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of xyloglucan catabolism							tt	2011-08-01T02:20:26Z					biological_process											owl:Class	
GO:0030255	biolink:NamedThing	protein secretion by the type IV secretion system	The process in which proteins are transferred into the extracellular milieu or directly into host cells, via the type IV protein secretion system.	tmpzr1t_l9r_go_relaxed.owl	protein secretion by the type IV protein secretion system|type IV protein secretion system|protein secretion by the T4SS					Note that this term represents an activity and not a cellular structure. Consider also annotating to the cellular component term 'type IV protein secretion system complex ; GO:0043684'.								biological_process											owl:Class	
GO:1901738	biolink:NamedThing	regulation of vitamin A metabolic process	Any process that modulates the frequency, rate or extent of vitamin A metabolic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of vitamin A metabolism							dph	2013-01-11T15:29:43Z					biological_process											owl:Class	
GO:0060616	biolink:NamedThing	mammary gland cord formation	The process in which the mammary gland cord forms by elongation of the mammary bud. The cord is formed once the elongating bud breaks through the mesenchyme and reaches the fat pad.	tmpzr1t_l9r_go_relaxed.owl	mammary gland sprout formation							dph	2009-05-18T08:57:58Z					biological_process											owl:Class	
GO:0060596	biolink:NamedThing	mammary placode formation	The developmental process in which the mammary placode forms. The mammary placode is a transient lens shaped structure that will give rise to the mammary bud proper.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-05-13T11:55:20Z					biological_process											owl:Class	
GO:0006716	biolink:NamedThing	juvenile hormone metabolic process	The chemical reactions and pathways involving juvenile hormones, the three sesquiterpenoid derivatives that function to maintain the larval state of insects at molting and that may be required for other processes, e.g. oogenesis.	tmpzr1t_l9r_go_relaxed.owl	juvenile hormone metabolism													biological_process											owl:Class	
GO:1901998	biolink:NamedThing	toxin transport	The directed movement of a toxin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl								dph	2013-03-19T19:24:55Z					biological_process											owl:Class	
GO:0072251	biolink:NamedThing	metanephric juxtaglomerulus cell differentiation	The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the juxtaglomerulus cells of the metanephros as it progresses from its formation to the mature state.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-03-19T03:54:35Z					biological_process											owl:Class	
GO:0072202	biolink:NamedThing	cell differentiation involved in metanephros development	The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the metanephros as it progresses from its formation to the mature state.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-03-18T10:40:14Z					biological_process											owl:Class	
GO:0018718	biolink:NamedThing	1,2-dihydroxy-phenanthrene glycosyltransferase activity	Catalysis of the reaction: 1,2-dihydroxyphenanthrene + UDP-glucose = 2-hydroxy-1-phenanthryl-beta-D-glucopyranoside + UDP.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0569									molecular_function											owl:Class	
GO:0071877	biolink:NamedThing	regulation of adenylate cyclase-inhibiting adrenergic receptor signaling pathway	Any process that modulates the frequency, rate or extent of an adenylate cyclase-inhibiting adrenergic receptor signaling pathway activity. An adrenergic receptor signaling pathway is the series of molecular signals generated as a consequence of an adrenergic receptor binding to one of its physiological ligands.	tmpzr1t_l9r_go_relaxed.owl	regulation of adrenergic receptor signaling pathway|regulation of adrenergic receptor signalling pathway							mah	2010-09-13T04:12:10Z					biological_process											owl:Class	
GO:0030564	biolink:NamedThing	tRNA 2'-O-ribose methylation guide activity	Specifies the site of 2'-O-ribose methylation in a tRNA molecule by base pairing with a short sequence around the target residue.	tmpzr1t_l9r_go_relaxed.owl						Note that this term describes the activity of a nucleic acid, usually RNA, gene product that interacts with other RNA molecules via base pairing; it should not be used to annotate proteins.								molecular_function											owl:Class	
GO:0030561	biolink:NamedThing	RNA 2'-O-ribose methylation guide activity	Specifies the site of 2'-O-ribose methylation in an RNA molecule by base pairing with a short sequence around the target residue.	tmpzr1t_l9r_go_relaxed.owl						Note that this term describes the activity of a nucleic acid, usually RNA, gene product that interacts with other RNA molecules via base pairing; it should not be used to annotate proteins.								molecular_function											owl:Class	
GO:0043513	biolink:NamedThing	inhibin B complex	Heterodimeric hormone composed of an inhibin alpha subunit complexed with an inhibin beta-B subunit.	tmpzr1t_l9r_go_relaxed.owl						Note that the actions of the inhibin complex are the opposite of those of the activin complex, which is a dimer of an inhibin beta-A and/or inhibin beta-B subunit. See also the cellular component term 'activin complex ; GO:0048180'.								cellular_component											owl:Class	
GO:0043511	biolink:NamedThing	inhibin complex	Heterodimeric hormone composed of an inhibin alpha subunit complexed with either an inhibin beta-A subunit, to form inhibin A, or an inhibin beta-B subunit, to form inhibin B.	tmpzr1t_l9r_go_relaxed.owl						Note that the actions of the inhibin complex are the opposite of those of the activin complex, which is a dimer of an inhibin beta-A and/or inhibin beta-B subunit. See also the cellular component term 'activin complex ; GO:0048180'.								cellular_component											owl:Class	
GO:0052723	biolink:NamedThing	inositol hexakisphosphate 1-kinase activity	Catalysis of the reaction: ATP + 1D-myo-inositol hexakisphosphate = ADP + 1-diphospho-1D-myo-inositol (2,3,4,5,6)pentakisphosphate.	tmpzr1t_l9r_go_relaxed.owl					EC:2.7.4.21|RHEA:37459|MetaCyc:RXN-10972|KEGG_REACTION:R05799			ai	2011-08-16T11:47:36Z					molecular_function											owl:Class	
GO:0036372	biolink:NamedThing	opsin transport	The directed movement of an opsin (a G protein-coupled receptor of photoreceptor cells) into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	ciliary transport of opsin							bf	2013-04-23T09:26:29Z					biological_process											owl:Class	
GO:0001870	biolink:NamedThing	positive regulation of complement activation, lectin pathway	Any process that activates or increases the frequency, rate or extent of complement activation by the lectin pathway.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of complement cascade, lectin pathway|stimulation of complement activation, lectin pathway|activation of complement activation, lectin pathway|up regulation of complement activation, lectin pathway|upregulation of complement activation, lectin pathway|up-regulation of complement activation, lectin pathway													biological_process											owl:Class	
GO:0099605	biolink:NamedThing	regulation of action potential firing rate	Any process that regulates the frequency of action potentials in a spike train.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1905835	biolink:NamedThing	cellular response to pyrimidine ribonucleotide	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pyrimidine ribonucleotide stimulus.	tmpzr1t_l9r_go_relaxed.owl								sl	2017-01-17T19:24:09Z					biological_process											owl:Class	
GO:2000833	biolink:NamedThing	positive regulation of steroid hormone secretion	Any process that activates or increases the frequency, rate or extent of steroid hormone secretion.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-07-26T08:38:51Z					biological_process											owl:Class	
GO:0046887	biolink:NamedThing	positive regulation of hormone secretion	Any process that activates or increases the frequency, rate or extent of the regulated release of a hormone from a cell.	tmpzr1t_l9r_go_relaxed.owl	upregulation of hormone secretion|up-regulation of hormone secretion|stimulation of hormone secretion|activation of hormone secretion|up regulation of hormone secretion													biological_process											owl:Class	
GO:1990694	biolink:NamedThing	intrinsic component of Golgi medial cisterna membrane	The component of the Golgi medial cisterna membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.	tmpzr1t_l9r_go_relaxed.owl	intrinsic component of medial-Golgi cisterna membrane							bhm	2015-03-12T10:29:12Z					cellular_component											owl:Class	
GO:0070381	biolink:NamedThing	endosome to plasma membrane transport vesicle	A transport vesicle that mediates transport from the endosome to the plasma membrane, and fuses with the plasma membrane to deliver lipids and membrane proteins to the plasma membrane  and to release various cargo molecules, such as proteins or hormones, by exocytosis.	tmpzr1t_l9r_go_relaxed.owl	endosome-plasma membrane transport vesicle|endosome to plasma membrane constitutive secretory pathway transport vesicle													cellular_component											owl:Class	
GO:0035971	biolink:NamedThing	peptidyl-histidine dephosphorylation	The removal of phosphoric residues from peptidyl-O-phospho-L-histidine to form peptidyl-histidine.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-08-08T03:26:02Z					biological_process											owl:Class	
GO:1904361	biolink:NamedThing	positive regulation of spore germination	Any process that activates or increases the frequency, rate or extent of spore germination.	tmpzr1t_l9r_go_relaxed.owl	upregulation of spore germination|up regulation of spore germination|positive regulation of spore germination on or near host|up-regulation of spore germination|activation of spore germination							pf	2015-06-12T19:46:18Z			GO:0075007		biological_process											owl:Class	
GO:0090384	biolink:NamedThing	phagosome-lysosome docking	The initial attachment of a phagosome membrane to a lysosome membrane. Docking requires only that the proteins come close enough to interact and adhere.	tmpzr1t_l9r_go_relaxed.owl	lysosome recruitment to phagosome							tb	2010-10-27T10:24:28Z					biological_process											owl:Class	
GO:0048278	biolink:NamedThing	vesicle docking	The initial attachment of a transport vesicle membrane to the target membrane, mediated by proteins protruding from the membrane of the vesicle and the target membrane. Docking requires only that the two membranes come close enough for these proteins to interact and adhere.	tmpzr1t_l9r_go_relaxed.owl	vesicle to membrane docking													biological_process											owl:Class	
GO:0097185	biolink:NamedThing	cellular response to azide	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an azide stimulus.	tmpzr1t_l9r_go_relaxed.owl								pr	2011-11-16T10:04:41Z					biological_process											owl:Class	
GO:0009263	biolink:NamedThing	deoxyribonucleotide biosynthetic process	The chemical reactions and pathways resulting in the formation of a deoxyribonucleotide, a compound consisting of deoxyribonucleoside (a base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.	tmpzr1t_l9r_go_relaxed.owl	deoxyribonucleotide biosynthesis|deoxyribonucleotide anabolism|deoxyribonucleotide synthesis|deoxyribonucleotide formation													biological_process											owl:Class	
GO:0018232	biolink:NamedThing	peptide cross-linking via S-(L-isoglutamyl)-L-cysteine	The modification of peptidyl-glutamine and peptidyl-cysteine to form a S-(L-isoglutamyl)-L-cysteine protein cross-link.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0108									biological_process											owl:Class	
GO:0030157	biolink:NamedThing	pancreatic juice secretion	The regulated release of pancreatic juice by the exocrine pancreas into the upper part of the intestine. Pancreatic juice is slightly alkaline and contains numerous enzymes and inactive enzyme precursors including alpha-amylase, chymotrypsinogen, lipase, procarboxypeptidase, proelastase, prophospholipase A2, ribonuclease, and trypsinogen. Its high concentration of bicarbonate ions helps to neutralize the acid from the stomach.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:2001160	biolink:NamedThing	regulation of histone H3-K79 methylation	Any process that modulates the frequency, rate or extent of histone H3-K79 methylation.	tmpzr1t_l9r_go_relaxed.owl	regulation of histone H3K79me|regulation of histone lysine H3 K79 methylation|regulation of histone H3 K79 methylation							se	2011-10-25T10:27:00Z					biological_process											owl:Class	
GO:0098795	biolink:NamedThing	mRNA destabilization-mediated gene silencing	A gene silencing mechanism that involves the destabilization of an mRNA.	tmpzr1t_l9r_go_relaxed.owl	mRNA cleavage involved in gene silencing	https://github.com/geneontology/go-ontology/issues/22389												biological_process											owl:Class	
GO:0016441	biolink:NamedThing	posttranscriptional gene silencing	The inactivation of gene expression by a posttranscriptional mechanism.	tmpzr1t_l9r_go_relaxed.owl	PTGS|cosuppression|post-transcriptional gene silencing|quelling	https://github.com/geneontology/go-ontology/issues/22202			Wikipedia:Post_transcriptional_gene_silencing									biological_process											owl:Class	
GO:0007100	biolink:NamedThing	mitotic centrosome separation	Separation of duplicated centrosome components at the beginning of mitosis. The centriole pair within each centrosome becomes part of a separate microtubule organizing center that nucleates a radial array of microtubules called an aster. The two asters move to opposite sides of the nucleus to form the two poles of the mitotic spindle.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0009141	biolink:NamedThing	nucleoside triphosphate metabolic process	The chemical reactions and pathways involving a nucleoside triphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with triphosphate on the sugar.	tmpzr1t_l9r_go_relaxed.owl	nucleoside triphosphate metabolism													biological_process											owl:Class	
GO:0006753	biolink:NamedThing	nucleoside phosphate metabolic process	The chemical reactions and pathways involving any phosphorylated nucleoside.	tmpzr1t_l9r_go_relaxed.owl	nucleoside phosphate metabolism													biological_process											owl:Class	
GO:0070845	biolink:NamedThing	polyubiquitinated misfolded protein transport	The directed movement of misfolded polyubiquitinated proteins in a cell, including the movement of proteins between specific compartments or structures within a cell.	tmpzr1t_l9r_go_relaxed.owl	polyubiquitylated misfolded protein transport|misfolded polyubiquitinated protein transport							mah	2009-07-31T12:52:26Z					biological_process											owl:Class	
GO:0070844	biolink:NamedThing	polyubiquitinated protein transport	The directed movement of polyubiquitinated proteins in a cell, including the movement of proteins between specific compartments or structures within a cell.	tmpzr1t_l9r_go_relaxed.owl	polyubiquitylated protein transport							mah	2009-07-31T12:51:10Z					biological_process											owl:Class	
GO:0080024	biolink:NamedThing	indolebutyric acid metabolic process	The chemical reactions and pathways involving indolebutyric acid, a compound that serves as an active or storage form of the hormone indole-3-acetic acid (an auxin) in many plants.	tmpzr1t_l9r_go_relaxed.owl	IBA metabolic process|indole-3-butyric acid metabolic process|IBA metabolism													biological_process											owl:Class	
GO:0120029	biolink:NamedThing	proton export across plasma membrane	The directed movement of hydrogen ions (protons) from inside a cell, across the plasma membrane and into the extracellular region.	tmpzr1t_l9r_go_relaxed.owl	proton export from cell|hydrogen ion export from cell|hydrogen ion export across plasma membrane							krc	2017-03-31T17:39:03Z					biological_process											owl:Class	
GO:1900778	biolink:NamedThing	fumiquinazoline A biosynthetic process	The chemical reactions and pathways resulting in the formation of fumiquinazoline A.	tmpzr1t_l9r_go_relaxed.owl	fumiquinazoline A synthesis|fumiquinazoline A anabolism|fumiquinazoline A biosynthesis|fumiquinazoline A formation							di	2012-06-04T09:30:25Z					biological_process											owl:Class	
GO:0006176	biolink:NamedThing	dATP biosynthetic process from ADP	The chemical reactions and pathways resulting in the formation of dATP, deoxyadenosine triphosphate (2'-deoxyadenosine 5'-triphosphate) from other compounds, including ADP, adenosine diphosphate.	tmpzr1t_l9r_go_relaxed.owl	dATP synthesis from ADP|dATP anabolism from ADP|dATP formation from ADP													biological_process											owl:Class	
GO:0046031	biolink:NamedThing	ADP metabolic process	The chemical reactions and pathways involving ADP, adenosine 5'-diphosphate.	tmpzr1t_l9r_go_relaxed.owl	ADP metabolism													biological_process											owl:Class	
GO:1903740	biolink:NamedThing	positive regulation of phosphatidate phosphatase activity	Any process that activates or increases the frequency, rate or extent of phosphatidate phosphatase activity.	tmpzr1t_l9r_go_relaxed.owl	upregulation of phosphatic acid phosphatase activity|activation of phosphatidate phosphohydrolase activity|up regulation of acid phosphatidyl phosphatase activity|positive regulation of acid phosphatidyl phosphatase activity|up regulation of phosphatic acid phosphatase activity|up regulation of phosphatidate phosphatase activity|up regulation of phosphatidate phosphohydrolase activity|upregulation of 3-sn-phosphatidate phosphohydrolase activity|up-regulation of 3-sn-phosphatidate phosphohydrolase activity|upregulation of acid phosphatidyl phosphatase activity|up regulation of phosphatidic acid phosphatase activity|upregulation of phosphatidate phosphatase activity|activation of phosphatic acid phosphatase activity|activation of 3-sn-phosphatidate phosphohydrolase activity|activation of phosphatidic acid phosphatase activity|activation of phosphatidate phosphatase activity|activation of acid phosphatidyl phosphatase activity|activation of phosphatic acid phosphohydrolase activity|upregulation of phosphatic acid phosphohydrolase activity|upregulation of phosphatidic acid phosphatase activity|positive regulation of 3-sn-phosphatidate phosphohydrolase activity|positive regulation of phosphatidate phosphohydrolase activity|up-regulation of phosphatidic acid phosphatase activity|up-regulation of phosphatidate phosphatase activity|upregulation of phosphatidate phosphohydrolase activity|positive regulation of phosphatidic acid phosphatase activity|positive regulation of phosphatic acid phosphohydrolase activity|up-regulation of phosphatidate phosphohydrolase activity|up regulation of 3-sn-phosphatidate phosphohydrolase activity|up-regulation of phosphatic acid phosphatase activity|up regulation of phosphatic acid phosphohydrolase activity|up-regulation of phosphatic acid phosphohydrolase activity|up-regulation of acid phosphatidyl phosphatase activity|positive regulation of phosphatic acid phosphatase activity							tb	2014-12-11T23:37:44Z					biological_process											owl:Class	
GO:0034173	biolink:NamedThing	positive regulation of toll-like receptor 11 signaling pathway	Any process that activates or increases the frequency, rate, or extent of toll-like receptor 11 signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of TLR11 signaling pathway|positive regulation of toll-like receptor 11 signalling pathway													biological_process											owl:Class	
GO:0004153	biolink:NamedThing	dihydropterin deaminase activity	Catalysis of the reaction: 7,8-dihydropterin + H2O = 7,8-dihydrolumazine + NH3.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0036302	biolink:NamedThing	atrioventricular canal development	The progression of the atrioventricular canal over time, from its formation to the mature structure. The atrioventricular canal is the part of the heart connecting the atrium to the cardiac ventricle.	tmpzr1t_l9r_go_relaxed.owl								bf	2012-08-08T09:55:37Z					biological_process											owl:Class	
GO:0019295	biolink:NamedThing	coenzyme M biosynthetic process	The chemical reactions and pathways resulting in the formation of coenzyme M (2-thioethansulfonate), a coenzyme involved in the utilization of methane by methanogenic prokaryotes.	tmpzr1t_l9r_go_relaxed.owl	coenzyme M anabolism|coenzyme M biosynthesis|coenzyme M synthesis|coenzyme M formation				MetaCyc:P261-PWY									biological_process											owl:Class	
GO:0009195	biolink:NamedThing	pyrimidine ribonucleoside diphosphate catabolic process	The chemical reactions and pathways resulting in the breakdown of pyrimidine ribonucleoside diphosphate, a compound consisting of a pyrimidine base linked to a ribose sugar esterified with diphosphate on the sugar.	tmpzr1t_l9r_go_relaxed.owl	pyrimidine ribonucleoside diphosphate catabolism|pyrimidine ribonucleoside diphosphate breakdown|pyrimidine ribonucleoside diphosphate degradation													biological_process											owl:Class	
GO:0009191	biolink:NamedThing	ribonucleoside diphosphate catabolic process	The chemical reactions and pathways resulting in the breakdown of a ribonucleoside diphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with diphosphate on the sugar.	tmpzr1t_l9r_go_relaxed.owl	ribonucleoside diphosphate degradation|ribonucleoside diphosphate catabolism|ribonucleoside diphosphate breakdown													biological_process											owl:Class	
GO:1905436	biolink:NamedThing	negative regulation of histone H3-K4 trimethylation	Any process that stops, prevents or reduces the frequency, rate or extent of histone H3-K4 trimethylation.	tmpzr1t_l9r_go_relaxed.owl	down regulation of histone H3-K4 trimethylation|downregulation of histone H3-K4 trimethylation|down-regulation of histone H3-K4 trimethylation|inhibition of histone H3-K4 trimethylation							hbye	2016-09-14T13:09:03Z					biological_process											owl:Class	
GO:0050259	biolink:NamedThing	ribose 1-dehydrogenase (NADP+) activity	Catalysis of the reaction: H(2)O + NADP(+) + ribofuranose = D-ribonate + 2 H(+) + NADPH.	tmpzr1t_l9r_go_relaxed.owl	NADP-pentose-dehydrogenase activity|D-ribose:NADP+ 1-oxidoreductase activity|D-ribose dehydrogenase (NADP+)				RHEA:11676|EC:1.1.1.115|KEGG_REACTION:R01079|MetaCyc:RIBOSE-1-DEHYDROGENASE-NADP+-RXN									molecular_function											owl:Class	
GO:0047140	biolink:NamedThing	glutathione-CoA-glutathione transhydrogenase activity	Catalysis of the reaction: oxidized glutathione + CoA = reduced glutathione + CoA-glutathione.	tmpzr1t_l9r_go_relaxed.owl	glutathione-coenzyme A glutathione disulfide transhydrogenase activity|CoA:glutathione-disulfide oxidoreductase activity|glutathione:coenzyme A-glutathione transhydrogenase activity|coenzyme A:oxidized-glutathione oxidoreductase activity|glutathione coenzyme A-glutathione transhydrogenase activity|coenzyme A:glutathione-disulfide oxidoreductase activity				EC:1.8.4.3|RHEA:13125|MetaCyc:1.8.4.3-RXN									molecular_function											owl:Class	
GO:0048029	biolink:NamedThing	monosaccharide binding	Binding to a monosaccharide. Monosaccharides are the simplest carbohydrates; they are polyhydroxy aldehydes H[CH(OH)]nC(=O)H or polyhydroxy ketones H[CHOH]nC(=O)[CHOH]mH with three or more carbon atoms. They form the constitutional repeating units of oligo- and polysaccharides.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0097741	biolink:NamedThing	mastigoneme	A hair-like structure covering the flagella found in some algae (heterokonts and cryptophytes). It is approximately 15 nm in diameter, and usually consist of a tubular shaft that itself terminates in smaller hairs. It is composed of glycoproteins and, likely, carbohydrates. Mastigonemes may assist in locomotion by increasing the surface area of a flagellum.	tmpzr1t_l9r_go_relaxed.owl								pr	2016-10-19T11:33:38Z					cellular_component											owl:Class	
GO:0099080	biolink:NamedThing	supramolecular complex	A cellular component that consists of an indeterminate number of proteins or macromolecular complexes, organized into a regular, higher-order structure such as a polymer, sheet, network or a fiber.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0048025	biolink:NamedThing	negative regulation of mRNA splicing, via spliceosome	Any process that stops, prevents or reduces the rate or extent of mRNA splicing via a spliceosomal mechanism.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of nuclear mRNA splicing, via spliceosome|inhibition of nuclear mRNA splicing, via spliceosome|negative regulation of pre-mRNA splicing|down regulation of nuclear mRNA splicing via U2-type spliceosome|downregulation of nuclear mRNA splicing via U2-type spliceosome|negative regulation of nuclear mRNA splicing via U2-type spliceosome|downregulation of nuclear mRNA splicing, via spliceosome|inhibition of nuclear mRNA splicing via U2-type spliceosome|down-regulation of nuclear mRNA splicing via U2-type spliceosome|down regulation of nuclear mRNA splicing, via spliceosome|negative regulation of nuclear mRNA splicing, via spliceosome											GO:0035056		biological_process											owl:Class	
GO:0033119	biolink:NamedThing	negative regulation of RNA splicing	Any process that stops, prevents, or reduces the frequency, rate or extent of RNA splicing.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0044719	biolink:NamedThing	regulation of imaginal disc-derived wing size	Any process that modulates the size of an imaginal disc-derived wing.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-10-18T13:49:12Z					biological_process											owl:Class	
GO:0001777	biolink:NamedThing	T cell homeostatic proliferation	The non-specific expansion of T cell populations within a whole or part of an organism to reach to a total number of T cells which will then remain stable over time in the absence of an external stimulus.	tmpzr1t_l9r_go_relaxed.owl	T-lymphocyte homeostatic proliferation|resting T cell proliferation|resting T-cell proliferation|T-cell homeostatic proliferation|T lymphocyte homeostatic proliferation													biological_process											owl:Class	
GO:0008038	biolink:NamedThing	neuron recognition	The process in which a neuronal cell in a multicellular organism interprets its surroundings.	tmpzr1t_l9r_go_relaxed.owl	neuronal cell recognition													biological_process											owl:Class	
GO:0008037	biolink:NamedThing	cell recognition	The process in which a cell in an organism interprets its surroundings.	tmpzr1t_l9r_go_relaxed.owl	recognition of surroundings by cell													biological_process											owl:Class	
GO:0034009	biolink:NamedThing	isoprene synthase activity	Catalysis of the reaction: dimethylallyl diphosphate = diphosphate + isoprene.	tmpzr1t_l9r_go_relaxed.owl	ISPC|ISPS|dimethylallyl-diphosphate diphosphate-lyase (isoprene-forming) activity				MetaCyc:4.2.3.27-RXN|EC:4.2.3.27|KEGG_REACTION:R08199|RHEA:13369									molecular_function											owl:Class	
GO:0050819	biolink:NamedThing	negative regulation of coagulation	Any process that stops, prevents, or reduces the frequency, rate or extent of coagulation.	tmpzr1t_l9r_go_relaxed.owl	down regulation of coagulation|anticoagulant activity|downregulation of coagulation|negative regulation of clotting|down-regulation of coagulation|inhibition of coagulation													biological_process											owl:Class	
GO:0070948	biolink:NamedThing	regulation of neutrophil mediated cytotoxicity	Any process that modulates the rate, frequency or extent of neutrophil mediated killing of a target cell, the directed killing of a target cell by a neutrophil.	tmpzr1t_l9r_go_relaxed.owl	regulation of neutrophil mediated cell killing							mah	2009-10-01T02:14:36Z					biological_process											owl:Class	
GO:0048502	biolink:NamedThing	ABC-type thiamine transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + thiamine(out) = ADP + H(+) + phosphate + thiamine(in).	tmpzr1t_l9r_go_relaxed.owl	thiamin-transporting ATPase activity|thiamine ABC transporter|thiamin pyrophosphate ABC transporter|thiamin pyrophosphate porter activity|thiamine-transporting ATPase activity|thiamine pyrophosphate-transporting ATPase activity|TPP transporting ATPase activity|thiamin pyrophosphate transporting ATPase activity|ATPase-coupled thiamine transmembrane transporter activity|ATP-dependent thiamine transmembrane transporter activity				RHEA:29811|EC:7.6.2.15|TC:3.A.1.19.1							GO:0015619		molecular_function											owl:Class	
GO:0048709	biolink:NamedThing	oligodendrocyte differentiation	The process in which a relatively unspecialized cell acquires the specialized features of an oligodendrocyte. An oligodendrocyte is a type of glial cell involved in myelinating the axons of neurons in the central nervous system.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:2001067	biolink:NamedThing	pullulan binding	Binding to pullulan.	tmpzr1t_l9r_go_relaxed.owl								jl	2011-09-14T11:50:06Z					molecular_function											owl:Class	
GO:0051333	biolink:NamedThing	meiotic nuclear membrane reassembly	The cell cycle process in which the reformation of the nuclear membranes during meiosis occurs.	tmpzr1t_l9r_go_relaxed.owl	meiotic nuclear envelope reassembly	https://github.com/geneontology/go-ontology/issues/20636												biological_process											owl:Class	
GO:0006558	biolink:NamedThing	L-phenylalanine metabolic process	The chemical reactions and pathways involving L-phenylalanine, the L-enantiomer of 2-amino-3-phenylpropanoic acid, i.e. (2S)-2-amino-3-phenylpropanoic acid.	tmpzr1t_l9r_go_relaxed.owl	phenylalanine metabolism|L-phenylalanine metabolism|phenylalanine metabolic process													biological_process											owl:Class	
GO:0097654	biolink:NamedThing	platelet SNARE complex	A SNARE complex that is capable of fusing intracellular vesicles to the plasma membrane of platelets for exocytosis of alpha-granules or dense granules. Contains isoforms of VAMP, SNAP and syntaxin proteins. Ternary SNARE complexes interact in a circular array to form ring complexes or channels around the membrane fusion. A common composition in human is VAMP-8, SNAP-23 and syntaxin-2 or -4.	tmpzr1t_l9r_go_relaxed.owl								pr	2014-09-24T13:50:49Z					cellular_component											owl:Class	
GO:0042313	biolink:NamedThing	protein kinase C deactivation	Any process resulting in the inhibition or termination of the activity of protein kinase C.	tmpzr1t_l9r_go_relaxed.owl	PKC deactivation													biological_process											owl:Class	
GO:1902811	biolink:NamedThing	positive regulation of skeletal muscle fiber differentiation	Any process that activates or increases the frequency, rate or extent of skeletal muscle fiber differentiation.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of skeletal muscle fiber differentiation|up regulation of skeletal muscle fiber differentiation|upregulation of skeletal muscle fiber differentiation|activation of skeletal muscle fiber differentiation							mr	2014-03-26T21:18:38Z					biological_process											owl:Class	
GO:2000762	biolink:NamedThing	regulation of phenylpropanoid metabolic process	Any process that modulates the frequency, rate or extent of phenylpropanoid metabolic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of phenylpropanoid metabolism							tb	2011-06-17T06:13:43Z					biological_process											owl:Class	
GO:0046539	biolink:NamedThing	histamine N-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine(1+) + histamine = N(tau)-methylhistamine + S-adenosyl-L-homocysteine + H(+).	tmpzr1t_l9r_go_relaxed.owl	imidazolemethyltransferase activity|S-adenosyl-L-methionine:histamine N-tele-methyltransferase activity|histamine-methylating enzyme|histamine 1-methyltransferase activity|histamine methyltransferase activity|S-adenosylmethionine-histamine N-methyltransferase activity				KEGG_REACTION:R02155|MetaCyc:HISTAMINE-N-METHYLTRANSFERASE-RXN|RHEA:19301|EC:2.1.1.8|Reactome:R-HSA-175993									molecular_function											owl:Class	
GO:1905621	biolink:NamedThing	positive regulation of alpha-(1->3)-fucosyltransferase activity	Any process that activates or increases the frequency, rate or extent of alpha-(1->3)-fucosyltransferase activity.	tmpzr1t_l9r_go_relaxed.owl	activation of alpha-(1->3)-fucosyltransferase activity|activation of alpha-1,3-fucosyltransferase activity|up-regulation of alpha-1,3-fucosyltransferase activity|up-regulation of alpha-(1,3)-fucosyltransferase activity|up regulation of alpha-1,3-fucosyltransferase activity|upregulation of alpha-(1,3)-fucosyltransferase activity|up regulation of alpha-(1->3)-fucosyltransferase activity|upregulation of alpha-1,3-fucosyltransferase activity|upregulation of alpha-(1->3)-fucosyltransferase activity|positive regulation of alpha(1,3)-fucosyltransferase activity|activation of alpha-(1,3)-fucosyltransferase activity|up regulation of alpha(1,3)-fucosyltransferase activity|upregulation of alpha(1,3)-fucosyltransferase activity|up-regulation of alpha-(1->3)-fucosyltransferase activity|up regulation of alpha-(1,3)-fucosyltransferase activity|activation of alpha(1,3)-fucosyltransferase activity|positive regulation of alpha-1,3-fucosyltransferase activity|positive regulation of alpha-(1,3)-fucosyltransferase activity|up-regulation of alpha(1,3)-fucosyltransferase activity							rz	2016-10-28T14:39:52Z					biological_process											owl:Class	
GO:1905619	biolink:NamedThing	regulation of alpha-(1->3)-fucosyltransferase activity	Any process that modulates the frequency, rate or extent of alpha-(1->3)-fucosyltransferase activity.	tmpzr1t_l9r_go_relaxed.owl	regulation of alpha-1,3-fucosyltransferase activity|regulation of alpha(1,3)-fucosyltransferase activity|regulation of alpha-(1,3)-fucosyltransferase activity							rz	2016-10-28T14:39:37Z					biological_process											owl:Class	
GO:0140211	biolink:NamedThing	folic acid:proton symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: folic acid(out) + H+(out) = folic acid(in) + H+(in). The main folic acid symporter is the Proton-Coupled Folate Transporter (PCFT/SLC46A1), which has similar affinity for transport of reduced folates (5-methyl THF, 5-formyl THF) and folic acid.	tmpzr1t_l9r_go_relaxed.owl					TC:2.A.1.50.1			pg	2018-03-30T08:00:09Z					molecular_function											owl:Class	
GO:0000297	biolink:NamedThing	spermine transmembrane transporter activity	Enables the transfer of spermine from one side of a membrane to the other. Spermine is a polybasic amine found in human sperm, in ribosomes and in some viruses, which is involved in nucleic acid packaging. Synthesis is regulated by ornithine decarboxylase which plays a key role in control of DNA replication.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0015203	biolink:NamedThing	polyamine transmembrane transporter activity	Enables the transfer of polyamines, organic compounds containing two or more amino groups, from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	amine/amide/polyamine channel activity													molecular_function											owl:Class	
GO:0045574	biolink:NamedThing	sterigmatocystin catabolic process	The chemical reactions and pathways resulting in the breakdown of sterigmatocystin, a carcinogenic mycotoxin produced in high yields by strains of the common molds.	tmpzr1t_l9r_go_relaxed.owl	sterigmatocystin degradation|sterigmatocystin catabolism|sterigmatocystin breakdown													biological_process											owl:Class	
GO:0006855	biolink:NamedThing	xenobiotic transmembrane transport	The process in which a xenobiotic, a compound foreign to the organim exposed to it, is transported across a membrane. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical.	tmpzr1t_l9r_go_relaxed.owl	drug transmembrane transport|drug membrane transport|multidrug transport	https://github.com/geneontology/go-ontology/issues/19460				Note that this term is not intended for use in annotating lateral movement within membranes.								biological_process											owl:Class	
GO:0042908	biolink:NamedThing	xenobiotic transport	The directed movement of a xenobiotic into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A xenobiotic is a compound foreign to the organim exposed to it. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical.	tmpzr1t_l9r_go_relaxed.owl	drug transport	https://github.com/geneontology/go-ontology/issues/19460										GO:0015893		biological_process											owl:Class	
GO:0001798	biolink:NamedThing	positive regulation of type IIa hypersensitivity	Any process that activates or increases the frequency, rate or extent of type IIa hypersensitivity, a type of inflammatory response.	tmpzr1t_l9r_go_relaxed.owl	upregulation of type IIa hypersensitivity|activation of type IIa hypersensitivity|up-regulation of type IIa hypersensitivity|stimulation of type IIa hypersensitivity|up regulation of type IIa hypersensitivity													biological_process											owl:Class	
GO:0050838	biolink:NamedThing	peptidyl-5-hydroxy-L-lysine trimethylation	The methylation of 5-hydroxy-L-lysine to form peptidyl-N6,N6,N6-trimethyl-5-hydroxy-L-lysine.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0359									biological_process											owl:Class	
GO:0018022	biolink:NamedThing	peptidyl-lysine methylation	The methylation of peptidyl-lysine to form either the mono-, di- or trimethylated derivative.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1901647	biolink:NamedThing	positive regulation of synoviocyte proliferation	Any process that activates or increases the frequency, rate or extent of synoviocyte proliferation.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of synoviocyte proliferation|activation of synoviocyte proliferation|upregulation of synoviocyte proliferation|up regulation of synoviocyte proliferation							hjd	2012-11-16T20:16:32Z					biological_process											owl:Class	
GO:0006505	biolink:NamedThing	GPI anchor metabolic process	The chemical reactions and pathways involving glycosylphosphatidylinositol anchors, molecular mechanisms for attaching membrane proteins to the lipid bilayer of cell membranes. Structurally they consist of a molecule of phosphatidylinositol to which is linked, via the C-6 hydroxyl of the inositol, a carbohydrate chain. This chain is in turn linked to the protein through an ethanolamine phosphate group, the amino group of which is in amide linkage with the C-terminal carboxyl of the protein chain, the phosphate group being esterified to the C-6 hydroxyl of the terminal mannose of the core carbohydrate chain.	tmpzr1t_l9r_go_relaxed.owl	GPI/GSI anchor metabolic process|glycosylphosphatidylinositol metabolism|GPI/GSI anchor metabolism|glycosylphosphatidylinositol metabolic process|GPI anchor metabolism											GO:0046472		biological_process											owl:Class	
GO:0036320	biolink:NamedThing	mating-type P-factor pheromone receptor activity	Combining with the mating-type peptide pheromone P-factor and transmitting the signal across the membrane to initiate a change in cell activity. P-factor is a polypeptide of 23 residues, with the sequence Thr-Tyr-Ala-Asp-Phe-Leu-Arg-Ala-Tyr-Gln-Ser-Trp-Asn-Thr-Phe-Val-Asn-Pro-Asp-Arg-Pro-Asn-Leu, and is a peptide pheromone released by Schizosaccharomyces pombe cells of the cellular mating type Plus.	tmpzr1t_l9r_go_relaxed.owl	P-factor mating pheromone receptor activity|P-factor receptor activity							bf	2012-08-30T16:55:30Z					molecular_function											owl:Class	
GO:0004932	biolink:NamedThing	mating-type factor pheromone receptor activity	Combining with a mating-type factor pheromone to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1900585	biolink:NamedThing	arugosin metabolic process	The chemical reactions and pathways involving arugosin.	tmpzr1t_l9r_go_relaxed.owl	arugosin metabolism							di	2012-05-15T06:48:15Z					biological_process											owl:Class	
GO:0016824	biolink:NamedThing	hydrolase activity, acting on acid halide bonds	Catalysis of the hydrolysis of any acid halide bond.	tmpzr1t_l9r_go_relaxed.owl					EC:3.8.-.-									molecular_function											owl:Class	
GO:0061610	biolink:NamedThing	glycerol to glycerone phosphate metabolic process	The chemical reactions and pathways in which glycerol, 1,2,3-propanetriol, is converted to glycerone phosphate.	tmpzr1t_l9r_go_relaxed.owl	glycerol metabolism to DHAP|glycerol metabolism to dihydroxyacetone phosphate|glycerol to DHAP metabolic process|glycerol to dihydroxyacetone phosphate metabolic process|glycerol metabolism to glycerone phosphate							dph	2014-04-03T13:26:21Z					biological_process											owl:Class	
GO:0006071	biolink:NamedThing	glycerol metabolic process	The chemical reactions and pathways involving glycerol, 1,2,3-propanetriol, a sweet, hygroscopic, viscous liquid, widely distributed in nature as a constituent of many lipids.	tmpzr1t_l9r_go_relaxed.owl	glycerol metabolism				MetaCyc:GLYCEROLMETAB-PWY									biological_process											owl:Class	
GO:0004045	biolink:NamedThing	aminoacyl-tRNA hydrolase activity	Catalysis of the reaction: N-substituted aminoacyl-tRNA + H2O = N-substituted amino acid + tRNA.	tmpzr1t_l9r_go_relaxed.owl	D-tyrosyl-tRNA hydrolase activity|aminoacyl-tRNA aminoacylhydrolase activity|peptidyl-tRNA hydrolase activity|N-substituted aminoacyl transfer RNA hydrolase activity|aminoacyl-tRNA hydrolase reaction|aminoacyl-transfer ribonucleate hydrolase activity				RHEA:54448|EC:3.1.1.29|MetaCyc:AMINOCYL-TRNA-HYDROLASE-RXN							GO:0019850|GO:0019851		molecular_function											owl:Class	
GO:0062113	biolink:NamedThing	early phagosome lumen	The volume enclosed by the membrane of an eary phagosome.	tmpzr1t_l9r_go_relaxed.owl	early phagocytic vesicle lumen							dph	2019-02-22T12:58:47Z					cellular_component											owl:Class	
GO:0097013	biolink:NamedThing	phagocytic vesicle lumen	The volume enclosed by the membrane of a phagocytic vesicle.	tmpzr1t_l9r_go_relaxed.owl								pr	2011-03-22T01:44:47Z					cellular_component											owl:Class	
GO:0033813	biolink:NamedThing	deacetylcephalosporin-C acetyltransferase activity	Catalysis of the reaction: acetyl-CoA + deacetylcephalosporin C = cephalosporin C + CoA.	tmpzr1t_l9r_go_relaxed.owl	DAC-AT|CPC acetylhydrolase activity|acetyl-CoA:deacetylcephalosporin-C acetyltransferase activity|acetyl-CoA:deacetylcephalosporin-C O-acetyltransferase activity|deacetylcephalosporin C acetyltransferase activity|acetyl-CoA:DAC O-acetyltransferase activity|acetyl-CoA:DAC acetyltransferase activity|cefG|DAC acetyltransferase activity|acetyl coenzyme A:DAC acetyltransferase activity				RHEA:23860|KEGG_REACTION:R03064|EC:2.3.1.175|MetaCyc:2.3.1.175-RXN									molecular_function											owl:Class	
GO:0051902	biolink:NamedThing	negative regulation of mitochondrial depolarization	Any process that stops, prevents, or reduces the frequency, rate or extent of the change in the membrane potential of the mitochondria from negative to positive.	tmpzr1t_l9r_go_relaxed.owl	down regulation of mitochondrial depolarization|down-regulation of mitochondrial depolarization|downregulation of mitochondrial depolarization|inhibition of mitochondrial depolarization													biological_process											owl:Class	
GO:0032744	biolink:NamedThing	positive regulation of interleukin-20 production	Any process that activates or increases the frequency, rate, or extent of interleukin-20 production.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of IL-20 production|stimulation of interleukin-20 production|upregulation of interleukin-20 production|up regulation of interleukin-20 production|up-regulation of interleukin-20 production|positive regulation of interleukin-20 biosynthetic process|activation of interleukin-20 production											GO:0045389		biological_process											owl:Class	
GO:0018494	biolink:NamedThing	carvone reductase activity	Catalysis of the reaction: carvone + 2 H+ + 2 e- = dihydrocarvone.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-9419|UM-BBD_reactionID:r0732|EC:1.3.99.25|MetaCyc:RXN-9403									molecular_function											owl:Class	
GO:0042574	biolink:NamedThing	retinal metabolic process	The chemical reactions and pathways involving retinal, a compound that plays an important role in the visual process in most vertebrates. In the retina, retinal combines with opsins to form visual pigments. Retinal is one of the forms of vitamin A.	tmpzr1t_l9r_go_relaxed.owl	retinal metabolism|retinaldehyde metabolic process|retinaldehyde metabolism													biological_process											owl:Class	
GO:1990412	biolink:NamedThing	hercynylselenocysteine lyase activity (selenoneine-forming)	Catalysis of the reaction: hercynylselenocysteine + 2H+ = selenoneine + pyruvate + ammonium.	tmpzr1t_l9r_go_relaxed.owl					RHEA:42696			mah	2014-07-02T15:51:07Z					molecular_function											owl:Class	
GO:0032968	biolink:NamedThing	positive regulation of transcription elongation from RNA polymerase II promoter	Any process that activates or increases the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides, catalyzed by RNA polymerase II.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of gene-specific transcription elongation from RNA polymerase II promoter|positive regulation of RNA elongation from RNA polymerase II promoter											GO:0090040		biological_process											owl:Class	
GO:0034121	biolink:NamedThing	regulation of toll-like receptor signaling pathway	Any process that modulates the frequency, rate, or extent of toll-like receptor signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	regulation of TLR signaling pathway|regulation of toll-like receptor signalling pathway													biological_process											owl:Class	
GO:0097020	biolink:NamedThing	COPII receptor activity	Binding specifically to a substance (cargo) to deliver it to a COPII transport vesicle. Cargo receptors span a membrane (either the plasma membrane or a vesicle membrane), binding simultaneously to cargo molecules and coat adaptors, to efficiently recruit soluble proteins to nascent vesicles.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/20002						pr	2011-03-24T04:19:55Z					molecular_function											owl:Class	
GO:0038024	biolink:NamedThing	cargo receptor activity	Binding specifically to a substance (cargo) to deliver it to a transport vesicle. Cargo receptors span a membrane (either the plasma membrane or a vesicle membrane), binding simultaneously to cargo molecules and coat adaptors, to efficiently recruit soluble proteins to nascent vesicles.	tmpzr1t_l9r_go_relaxed.owl	transport receptor activity|endocytic receptor activity|receptor activity|receptor activity involved in receptor-mediated endocytosis				Reactome:R-HSA-350168|Reactome:R-HSA-3000122	Notes: (1) this term and its child terms are intended for receptors that bind to and internalize molecules by receptor-mediated endocytosis. For receptors that are coupled to a signal transduction pathway, consider instead the term 'signaling receptor activity ; GO:0038023' and its children. (2) Cargo receptors transport substances by vesicular transport, not by transmembrane transport.  For transmembrane transporters, consider instead the term 'transmembrane transporter activity ; GO:0022857.		bf	2011-08-01T02:50:45Z					molecular_function											owl:Class	
GO:2000117	biolink:NamedThing	negative regulation of cysteine-type endopeptidase activity	Any process that stops, prevents, or reduces the frequency, rate or extent of cysteine-type endopeptidase activity.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of thiol endopeptidase activity|negative regulation of lysosomal cysteine-type endopeptidase							jl	2010-09-23T10:24:35Z					biological_process											owl:Class	
GO:0102435	biolink:NamedThing	myricetin 7-O-methyltransferase activity	Catalysis of the reaction: myricetin(1-) + S-adenosyl-L-methionine  <=> 7-O-methylmyricetin + S-adenosyl-L-homocysteine.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-13910									molecular_function											owl:Class	
GO:0050651	biolink:NamedThing	dermatan sulfate proteoglycan biosynthetic process	The chemical reactions and pathways resulting in the formation of dermatan sulfate proteoglycan, any glycoprotein whose glycosaminoglycan units are dermatan sulfate (chondroitin sulfate B). Dermatan sulfate is a glycosaminoglycan with repeats consisting of beta-(1,4)-linked L-iduronyl-beta-(1,3)-N-acetyl-D-galactosamine 4-sulfate units.	tmpzr1t_l9r_go_relaxed.owl	dermatan sulphate proteoglycan biosynthetic process|dermatan sulphate proteoglycan biosynthesis|dermatan sulfate proteoglycan anabolism|dermatan sulfate proteoglycan synthesis|dermatan sulfate proteoglycan formation|chondroitin sulfate B proteoglycan biosynthetic process|chondroitin sulfate B proteoglycan biosynthesis|dermatan sulfate proteoglycan biosynthesis													biological_process											owl:Class	
GO:1901409	biolink:NamedThing	positive regulation of phosphorylation of RNA polymerase II C-terminal domain	Any process that activates or increases the frequency, rate or extent of phosphorylation of RNA polymerase II C-terminal domain.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of phosphorylation of RNA polymerase II C-terminal domain|upregulation of generation of II(0) form of RNA polymerase II|activation of generation of hyperphosphorylated CTD of RNA polymerase II|up regulation of generation of II(0) form of RNA polymerase II|upregulation of CTD domain phosphorylation of RNA polymerase II|positive regulation of generation of II(0) form of RNA polymerase II|up regulation of CTD domain phosphorylation of RNA polymerase II|positive regulation of CTD domain phosphorylation of RNA polymerase II|up regulation of hyperphosphorylation of RNA polymerase II C-terminal domain|activation of CTD domain phosphorylation of RNA polymerase II|upregulation of hyperphosphorylation of RNA polymerase II C-terminal domain|upregulation of phosphorylation of RNA polymerase II C-terminal domain|up-regulation of hyperphosphorylation of RNA polymerase II C-terminal domain|activation of generation of II(0) form of RNA polymerase II|up-regulation of generation of II(0) form of RNA polymerase II|activation of hyperphosphorylation of RNA polymerase II C-terminal domain|up regulation of generation of hyperphosphorylated CTD of RNA polymerase II|activation of phosphorylation of RNA polymerase II C-terminal domain|positive regulation of generation of hyperphosphorylated CTD of RNA polymerase II|up regulation of phosphorylation of RNA polymerase II C-terminal domain|up-regulation of CTD domain phosphorylation of RNA polymerase II|up-regulation of generation of hyperphosphorylated CTD of RNA polymerase II|upregulation of generation of hyperphosphorylated CTD of RNA polymerase II|positive regulation of hyperphosphorylation of RNA polymerase II C-terminal domain							vw	2012-10-01T14:41:15Z					biological_process											owl:Class	
GO:0061065	biolink:NamedThing	regulation of dauer larval development	Any process that modulates the rate, frequency, or extent of dauer larval development, the process whose specific outcome is the progression of the dauer larva over time, through the facultative diapause of the dauer (enduring) larval stage, with specialized traits adapted for dispersal and long-term survival, with elevated stress resistance and without feeding.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-03-11T01:07:07Z					biological_process											owl:Class	
GO:0002403	biolink:NamedThing	T cell tolerance induction in mucosal-associated lymphoid tissue	Tolerance induction taking place in the mucosal-associated lymphoid tissue (MALT) mediated by T cells.	tmpzr1t_l9r_go_relaxed.owl	T cell tolerance induction in MALT													biological_process											owl:Class	
GO:0070214	biolink:NamedThing	CSK-GAP-A.p62 complex	A protein complex that contains the protein-tyrosine kinase CSK and the GTPase-activating protein (GAP)-associated p62 (GAP-A.p62); may mediate translocation of proteins, including GAP and CSK, to membrane or cytoskeletal regions upon c-Src activation.	tmpzr1t_l9r_go_relaxed.owl						Note that the gene/protein name 'APC' should not be confused with the abbreviation for 'anaphase promoting complex'.								cellular_component											owl:Class	
GO:1905653	biolink:NamedThing	positive regulation of artery morphogenesis	Any process that activates or increases the frequency, rate or extent of artery morphogenesis.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of arteriogenesis|activation of artery morphogenesis|upregulation of arterial morphogenesis|activation of arterial morphogenesis|up regulation of arteriogenesis|activation of arteriogenesis|positive regulation of arteriogenesis|up-regulation of arterial morphogenesis|upregulation of artery morphogenesis|up regulation of arterial morphogenesis|up-regulation of artery morphogenesis|positive regulation of arterial morphogenesis|up regulation of artery morphogenesis|upregulation of arteriogenesis							rph	2016-11-09T12:20:01Z					biological_process											owl:Class	
GO:0106002	biolink:NamedThing	mCRD-mediated mRNA stability complex	A protein complex that binds to, and promotes stabilization of, mRNA molecules containing the major coding region instability determinant (mCRD) by bridging the mCRD domain and the poly(A) tail of the mRNA. In human, it consists of CSDE1, HNRPD, PABPC1, PAIP1 and SYNCRIP.	tmpzr1t_l9r_go_relaxed.owl	major coding region instability determinant-mediated mRNA stability complex|major coding-region determinant of instability - poly(A) tail-bridging complex|mCRD-poly(A)-bridging complex|major coding region determinant of instability-mediated mRNA stability complex|major coding region instability determinant-poly(A)-bridging complex					This complex is related to GO:0070937 CRD-mediated mRNA stability complex but binds the major protein-coding-region determinant of instability (mCRD) domain rather than the CRD. Experimentally it has been shown to act on c-FOS mRNA while GO:0070937 acts on c-MYC mRNA.								cellular_component											owl:Class	
GO:1900834	biolink:NamedThing	regulation of emericellin biosynthetic process	Any process that modulates the frequency, rate or extent of emericellin biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of Variecoxanthone B synthesis|regulation of Variecoxanthone B biosynthetic process|regulation of emericellin synthesis|regulation of Variecoxanthone B formation|regulation of emericellin anabolism|regulation of emericellin formation|regulation of Variecoxanthone B biosynthesis|regulation of Variecoxanthone B anabolism|regulation of emericellin biosynthesis							di	2012-06-07T09:32:02Z					biological_process											owl:Class	
GO:0055086	biolink:NamedThing	nucleobase-containing small molecule metabolic process	The cellular chemical reactions and pathways involving a nucleobase-containing small molecule: a nucleobase, a nucleoside, or a nucleotide.	tmpzr1t_l9r_go_relaxed.owl	nucleobase, nucleoside and nucleotide metabolism|nucleobase, nucleoside and nucleotide metabolic process													biological_process											owl:Class	
GO:0098923	biolink:NamedThing	retrograde trans-synaptic signaling by soluble gas	Cell-cell signaling from postsynapse to presynapse, across the synaptic cleft, mediated by an soluble gas ligand.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0099543	biolink:NamedThing	trans-synaptic signaling by soluble gas	Cell-cell signaling between presynapse and postsynapse mediated by a soluble gas ligand crossing the synaptic cleft.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1902892	biolink:NamedThing	positive regulation of root hair elongation	Any process that activates or increases the frequency, rate or extent of root hair elongation.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of root hair elongation|up regulation of root hair elongation|activation of root hair elongation|upregulation of root hair elongation							als	2014-04-07T13:46:53Z					biological_process											owl:Class	
GO:0043647	biolink:NamedThing	inositol phosphate metabolic process	The chemical reactions and pathways involving inositol phosphate, 1,2,3,4,5,6-cyclohexanehexol, with one or more phosphate groups attached.	tmpzr1t_l9r_go_relaxed.owl	myo-inositol phosphate metabolism|inositol phosphate metabolism|myo-inositol phosphate metabolic process													biological_process											owl:Class	
GO:0048034	biolink:NamedThing	heme O biosynthetic process	The chemical reactions and pathways resulting in the formation of heme O, a derivative of heme containing a 17-carbon hydroxyethylfarnesyl side chain at position 8 of the tetrapyrrole macrocycle.	tmpzr1t_l9r_go_relaxed.owl	haem O biosynthetic process|heme O synthesis|haem O biosynthesis|heme O biosynthesis|heme O formation|heme O anabolism													biological_process											owl:Class	
GO:0048033	biolink:NamedThing	heme O metabolic process	The chemical reactions and pathways involving heme O, a derivative of heme containing a 17-carbon hydroxyethylfarnesyl side chain at position 8 of the tetrapyrrole macrocycle.	tmpzr1t_l9r_go_relaxed.owl	haem O metabolism|heme O metabolism|haem O metabolic process													biological_process											owl:Class	
GO:0031300	biolink:NamedThing	intrinsic component of organelle membrane	The component of the organelle membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.	tmpzr1t_l9r_go_relaxed.owl	intrinsic to organelle membrane													cellular_component											owl:Class	
GO:0031997	biolink:NamedThing	N-terminal myristoylation domain binding	Binding to the N-terminus of a protein that has the potential to be, or has been, modified by N-terminal myristoylation. Binding affinity is typically altered by myristoylation; for example, N-terminal myristoylation of HIV Nef increases its affinity for calmodulin.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0047485	biolink:NamedThing	protein N-terminus binding	Binding to a protein N-terminus, the end of any peptide chain at which the 2-amino (or 2-imino) function of a constituent amino acid is not attached in peptide linkage to another amino-acid residue.	tmpzr1t_l9r_go_relaxed.owl	amino-terminal binding|NH2-terminus binding|N-terminal binding|amino-terminus binding|N-terminal end binding|NH2-terminal binding													molecular_function											owl:Class	
GO:0001953	biolink:NamedThing	negative regulation of cell-matrix adhesion	Any process that stops, prevents, or reduces the rate or extent of cell adhesion to the extracellular matrix.	tmpzr1t_l9r_go_relaxed.owl	inhibition of cell-matrix adhesion|down-regulation of cell-matrix adhesion|downregulation of cell-matrix adhesion|down regulation of cell-matrix adhesion													biological_process											owl:Class	
GO:0045244	biolink:NamedThing	succinate-CoA ligase complex (GDP-forming)	A heterodimeric enzyme complex, usually composed of an alpha and beta chain. Functions in the TCA cycle, hydrolyzing succinyl-CoA into succinate and CoA, thereby forming GTP.	tmpzr1t_l9r_go_relaxed.owl	succinyl-CoA synthetase, GDP-forming											GO:0045245|GO:0008325		cellular_component											owl:Class	
GO:0002310	biolink:NamedThing	alpha-beta T cell proliferation involved in immune response	The expansion of an alpha-beta T cell population by cell division as part of an immune response.	tmpzr1t_l9r_go_relaxed.owl	alpha-beta T-lymphocyte proliferation during immune response|alpha-beta T lymphocyte proliferation during immune response|alpha-beta T-cell proliferation during immune response|alpha-beta T cell proliferation during immune response													biological_process											owl:Class	
GO:0052040	biolink:NamedThing	modulation by symbiont of host programmed cell death	Any process in which an organism modulates the frequency, rate or extent of programmed cell death in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	modulation by symbiont of host non-apoptotic programmed cell death|modulation of host PCD											GO:0052152		biological_process											owl:Class	
GO:0060182	biolink:NamedThing	apelin receptor activity	Combining with the peptide apelin to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0042683	biolink:NamedThing	negative regulation of compound eye cone cell fate specification	Any process that restricts, stops or prevents a cell from specifying into a compound eye cone cell.	tmpzr1t_l9r_go_relaxed.owl	suppression of cone cell fate|downregulation of cone cell fate specification|inhibition of cone cell fate specification|down-regulation of cone cell fate specification|down regulation of cone cell fate specification											GO:0010000		biological_process											owl:Class	
GO:0032275	biolink:NamedThing	luteinizing hormone secretion	The regulated release of luteinizing hormone, a gonadotropic glycoprotein hormone secreted by the anterior pituitary.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0032274	biolink:NamedThing	gonadotropin secretion	The regulated release of a gonadotropin, any hormone that stimulates the gonads, especially follicle-stimulating hormone and luteinizing hormone.	tmpzr1t_l9r_go_relaxed.owl	gonadotrophin secretion													biological_process											owl:Class	
GO:0005230	biolink:NamedThing	extracellular ligand-gated ion channel activity	Enables the transmembrane transfer of an ion by a channel that opens when a specific extracellular ligand has been bound by the channel complex or one of its constituent parts.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0010259	biolink:NamedThing	multicellular organism aging	An aging process that has as participant a whole multicellular organism. Multicellular organism aging includes loss of functions such as resistance to disease, homeostasis, and fertility, as well as wear and tear. Multicellular organisms aging includes processes like cellular senescence and organ senescence, but is more inclusive. May precede death (GO:0016265) of an organism and may succeed developmental maturation (GO:0021700).	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0007275	biolink:NamedThing	multicellular organism development	The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/21234				Note that this term was 'developmental process'.								biological_process											owl:Class	
GO:0035816	biolink:NamedThing	renal water absorption involved in negative regulation of urine volume	Any process where water is taken up from the collecting ducts and proximal and distal loops of the nephron, which acts to decrease the amount of urine that is excreted from the body per unit time.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-04-20T01:37:34Z					biological_process											owl:Class	
GO:0070295	biolink:NamedThing	renal water absorption	A renal system process in which water is taken up from the collecting ducts and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures.	tmpzr1t_l9r_go_relaxed.owl	nephron water absorption|renal water reabsorption													biological_process											owl:Class	
GO:0015799	biolink:NamedThing	propanediol transport	The directed movement of propanediol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Propanediol is a sweet colorless, viscous, hygroscopic liquid used as an antifreeze and in brake fluid; it is also as a humectant in cosmetics and personal care items, although it can be absorbed through the skin with harmful effects.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0016093	biolink:NamedThing	polyprenol metabolic process	The chemical reactions and pathways involving polyprenols, prenols with more than 4 isoprenoid residues, which may be all-trans, or a mixture of cis and trans.	tmpzr1t_l9r_go_relaxed.owl	polyprenol metabolism													biological_process											owl:Class	
GO:2001264	biolink:NamedThing	negative regulation of C-C chemokine binding	Any process that stops, prevents or reduces the frequency, rate or extent of C-C chemokine binding.	tmpzr1t_l9r_go_relaxed.owl								yaf	2011-12-09T01:14:01Z					biological_process											owl:Class	
GO:2001263	biolink:NamedThing	regulation of C-C chemokine binding	Any process that modulates the frequency, rate or extent of C-C chemokine binding.	tmpzr1t_l9r_go_relaxed.owl								yaf	2011-12-09T01:13:54Z					biological_process											owl:Class	
GO:0051493	biolink:NamedThing	regulation of cytoskeleton organization	Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures.	tmpzr1t_l9r_go_relaxed.owl	regulation of cytoskeleton organization and biogenesis|regulation of cytoskeleton organisation													biological_process											owl:Class	
GO:0003267	biolink:NamedThing	canonical Wnt signaling pathway involved in positive regulation of secondary heart field cardioblast proliferation	A canonical Wnt signaling pathway that contributes to an increase in the frequency, or rate of cardioblast proliferation in the secondary heart field. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.	tmpzr1t_l9r_go_relaxed.owl	canonical Wnt receptor signaling pathway involved in positive regulation of second heart field cardioblast proliferation|canonical Wnt receptor signalling pathway involved in positive regulation of secondary heart field cardioblast proliferation|canonical Wnt receptor signaling pathway involved in positive regulation of secondary heart field cardioblast proliferation|canonical Wnt-activated signaling pathway involved in positive regulation of secondary heart field cardioblast proliferation							dph	2009-10-15T02:36:08Z					biological_process											owl:Class	
GO:0046774	biolink:NamedThing	suppression by virus of host intracellular interferon activity	Any viral process that results in the inhibition of interferon activity within the host cell.	tmpzr1t_l9r_go_relaxed.owl	negative regulation by virus of intracellular interferon activity|suppression by virus of intracellular interferon activity in host													biological_process											owl:Class	
GO:0006337	biolink:NamedThing	nucleosome disassembly	The controlled breakdown of nucleosomes, the beadlike structural units of eukaryotic chromatin composed of histones and DNA.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0032986	biolink:NamedThing	protein-DNA complex disassembly	The disaggregation of a protein-DNA complex into its constituent components.	tmpzr1t_l9r_go_relaxed.owl	DNA-protein complex disassembly													biological_process											owl:Class	
GO:0033422	biolink:NamedThing	CCC codon-amino acid adaptor activity	A triplet codon-amino acid adaptor activity that recognizes a CCC codon.	tmpzr1t_l9r_go_relaxed.owl	proline tRNA					Note that in the standard genetic code, CCC codes for proline.								molecular_function											owl:Class	
GO:0019665	biolink:NamedThing	anaerobic amino acid catabolic process	The anaerobic chemical reactions and pathways resulting in the breakdown of amino acids, yielding energy in the form of ATP.	tmpzr1t_l9r_go_relaxed.owl	amino acid fermentation													biological_process											owl:Class	
GO:1903725	biolink:NamedThing	regulation of phospholipid metabolic process	Any process that modulates the frequency, rate or extent of phospholipid metabolic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of phospholipid metabolism							sl	2014-12-09T20:49:27Z					biological_process											owl:Class	
GO:0019599	biolink:NamedThing	(R)-4-hydroxymandelate catabolic process	The chemical reactions and pathways resulting in the breakdown of (R)-4-hydroxymandelate, the anion of (R)-4-hydroxymandelic acid.	tmpzr1t_l9r_go_relaxed.owl	(R)-4-hydroxymandelate breakdown|(R)-4-hydroxymandelate catabolism|(R)-4-hydroxymandelate degradation				MetaCyc:4-HYDROXYMANDELATE-DEGRADATION-PWY									biological_process											owl:Class	
GO:0010866	biolink:NamedThing	regulation of triglyceride biosynthetic process	Any process that modulates the rate, frequency, or extent of triglyceride biosynthesis. Triglyceride biosynthesis is the collection of chemical reactions and pathways resulting in the formation of triglyceride, any triester of glycerol.	tmpzr1t_l9r_go_relaxed.owl	regulation of triacylglycerol biosynthetic process													biological_process											owl:Class	
GO:0048190	biolink:NamedThing	wing disc dorsal/ventral pattern formation	The establishment, maintenance and elaboration of the dorsal/ventral axis of the wing disc, a precursor to the adult wing.	tmpzr1t_l9r_go_relaxed.owl	wing disc dorsoventral pattern formation|wing disc dorsal-ventral pattern formation													biological_process											owl:Class	
GO:0007450	biolink:NamedThing	dorsal/ventral pattern formation, imaginal disc	The establishment, maintenance and elaboration of the dorsal/ventral axis of the imaginal disc. Imaginal disks are masses of hypodermic cells, carried by the larvae of some insects after leaving the egg, from which masses the wings and legs of the adult are subsequently formed.	tmpzr1t_l9r_go_relaxed.owl	dorsal-ventral pattern formation, imaginal disc|dorsoventral pattern formation, imaginal disc													biological_process											owl:Class	
GO:0016091	biolink:NamedThing	prenol biosynthetic process	The chemical reactions and pathways resulting in the formation of prenols, isoprenoids of general formula (H-CH2-C(CH3)=CH-CH2-)n-OH, any primary monohydroxy alcohol whose carbon skeleton consists of two or more isoprenoid residues linked head to tail.	tmpzr1t_l9r_go_relaxed.owl	prenol biosynthesis|prenol synthesis|prenol formation|prenol anabolism													biological_process											owl:Class	
GO:0062025	biolink:NamedThing	regulation of SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	Any process that modualtes the rate, frequency or extent of SCF-dependent proteasomal ubiquitin-dependent protein catabolic process, the chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, with ubiquitin-protein ligation catalyzed by an SCF (Skp1/Cul1/F-box protein) complex, and mediated by the proteasome.	tmpzr1t_l9r_go_relaxed.owl								dph	2018-04-16T13:54:43Z					biological_process											owl:Class	
GO:0004784	biolink:NamedThing	superoxide dismutase activity	Catalysis of the reaction: 2 superoxide + 2 H+ = O2 + hydrogen peroxide.	tmpzr1t_l9r_go_relaxed.owl	superoxide:superoxide oxidoreductase activity|Mn, Fe superoxide dismutase|ferrisuperoxide dismutase activity|cuprein|SOD-2|hepatocuprein|Fe-SOD|SOD-3|iron superoxide oxidoreductase|SOD-1|Cu,Zn-SOD|SODS|iron superoxide dismutase activity|Cu-Zn superoxide dismutase activity|copper, zinc superoxide dismutase activity|Mn-SOD|nickel superoxide oxidoreductase|SOD|cytocuprein|SODF|erythrocuprein|superoxide dismutase I|manganese superoxide oxidoreductase|nickel superoxide dismutase activity|hemocuprein|SOD-4|manganese superoxide dismutase activity|superoxide dismutase II|zinc superoxide oxidoreductase				Reactome:R-HSA-3299680|MetaCyc:SUPEROX-DISMUT-RXN|Reactome:R-HSA-3299691|Reactome:R-HSA-1222469|Reactome:R-HSA-3299682|Reactome:R-HSA-1222462|RHEA:20696|Reactome:R-HSA-3777112|EC:1.15.1.1							GO:0008383|GO:0008382|GO:0016954|GO:0004785		molecular_function											owl:Class	
GO:1902819	biolink:NamedThing	ethyl acetate biosynthetic process	The chemical reactions and pathways resulting in the formation of ethyl acetate.	tmpzr1t_l9r_go_relaxed.owl	ethyl acetate biosynthesis|ethyl acetate synthesis|ethyl ethanoate biosynthetic process|ethyl acetate formation|ethyl acetate anabolism							tt	2014-03-30T20:26:53Z					biological_process											owl:Class	
GO:0044552	biolink:NamedThing	vasodilation in other organism	A process by which an organism causes vasodilation of blood vessels, usually causing a reduction in blood pressure, in another organism.	tmpzr1t_l9r_go_relaxed.owl	regulation of vasodilation in other organism|modulation of vasodilation in other organism							jl	2012-03-29T02:14:42Z					biological_process											owl:Class	
GO:0044553	biolink:NamedThing	modulation of biological quality in other organism	Any process that modulates the frequency, rate or extent of a biological quality in another organism. A biological quality is a measurable attribute of an organism or part of an organism, such as size, mass, shape, color, etc.	tmpzr1t_l9r_go_relaxed.owl	regulation of biological quality in other organism							jl	2012-03-29T02:35:03Z					biological_process											owl:Class	
GO:1901390	biolink:NamedThing	positive regulation of transforming growth factor beta activation	Any process that activates or increases the frequency, rate or extent of transforming growth factor beta activation.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of TGF-beta activation|upregulation of TGFB activation|activation of TGFB activation|activation of latent TGF-beta activation|up regulation of TGF-B activation|upregulation of L-TGF-beta activation|upregulation of transforming growth factor beta activation|positive regulation of TGF-B activation|activation of TGFbeta activation|upregulation of TGF-B activation|up-regulation of transforming growth factor beta activation|positive regulation of L-TGF-beta activation|up-regulation of TGFB activation|up regulation of TGF-beta activation|upregulation of TGFbeta activation|activation of TGF-B activation|activation of L-TGF-beta activation|positive regulation of TGFbeta activation|up regulation of latent TGF-beta activation|positive regulation of latent TGF-beta activation|up-regulation of TGF-B activation|activation of TGF-beta activation|positive regulation of TGFB activation|up-regulation of latent TGF-beta activation|up regulation of transforming growth factor beta activation|up regulation of L-TGF-beta activation|upregulation of latent TGF-beta activation|up regulation of TGFB activation|up-regulation of L-TGF-beta activation|up-regulation of TGFbeta activation|up regulation of TGFbeta activation|upregulation of TGF-beta activation|activation of transforming growth factor beta activation|up-regulation of TGF-beta activation							bf	2012-10-01T10:33:26Z					biological_process											owl:Class	
GO:0002822	biolink:NamedThing	regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	Any process that modulates the frequency, rate, or extent of an adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains. An example of this process is found in the Gnathostomata.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:2001129	biolink:NamedThing	methane biosynthetic process from dimethylamine	The chemical reactions and pathways resulting in the formation of a methane from a dimethylamine.	tmpzr1t_l9r_go_relaxed.owl								jl	2011-10-13T10:26:13Z					biological_process											owl:Class	
GO:1902757	biolink:NamedThing	bis(molybdopterin guanine dinucleotide)molybdenum metabolic process	The chemical reactions and pathways involving bis(molybdopterin guanine dinucleotide)molybdenum.	tmpzr1t_l9r_go_relaxed.owl	bis(molybdopterin guanine dinucleotide)molybdenum metabolism							dph	2014-03-06T13:58:10Z					biological_process											owl:Class	
GO:0016803	biolink:NamedThing	ether hydrolase activity	Catalysis of the hydrolysis of an ether bond, -O-.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-8874435|EC:3.3.2.-									molecular_function											owl:Class	
GO:0016801	biolink:NamedThing	hydrolase activity, acting on ether bonds	Catalysis of the hydrolysis of any ether or thioether bond, -O- or -S- respectively.	tmpzr1t_l9r_go_relaxed.owl					EC:3.3.-.-									molecular_function											owl:Class	
GO:0033688	biolink:NamedThing	regulation of osteoblast proliferation	Any process that modulates the frequency, rate or extent of osteoblast proliferation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0009626	biolink:NamedThing	plant-type hypersensitive response	The rapid, localized death of plant cells in response to invasion by a pathogen.	tmpzr1t_l9r_go_relaxed.owl	HR-PCD|plant hypersensitive response|HR					Note that term is to be used to annotate gene products in the plant. To annotate symbiont gene products that induce the hypersensitive response, consider the biological process term 'modulation by symbiont of host defense-related programmed cell death ; GO:0034053'.								biological_process											owl:Class	
GO:0090082	biolink:NamedThing	positive regulation of heart induction by negative regulation of canonical Wnt signaling pathway	Any process that decreases the rate, frequency or extent of canonical Wnt signaling pathway that positively regulates heart induction. Canonical Wnt signaling pathway involved in heart induction is the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of heart induction by negative regulation of canonical Wnt receptor signalling pathway|positive regulation of heart induction by negative regulation of canonical Wnt-activated signaling pathway|positive regulation of heart induction by negative regulation of canonical Wnt receptor signaling pathway							tb	2009-10-23T10:58:03Z					biological_process											owl:Class	
GO:1901651	biolink:NamedThing	regulation of mitotic chromosome decondensation	Any process that modulates the frequency, rate or extent of mitotic chromosome decondensation.	tmpzr1t_l9r_go_relaxed.owl								dph	2012-11-19T14:13:58Z					biological_process											owl:Class	
GO:0042586	biolink:NamedThing	peptide deformylase activity	Catalysis of the reaction: formyl-L-methionyl peptide + H2O = formate + methionyl peptide.	tmpzr1t_l9r_go_relaxed.owl	PDF activity|polypeptide deformylase activity|formyl-L-methionyl peptide amidohydrolase activity				EC:3.5.1.88|MetaCyc:3.5.1.88-RXN|RHEA:24420									molecular_function											owl:Class	
GO:1900511	biolink:NamedThing	positive regulation of pentose catabolic process to ethanol	Any process that activates or increases the frequency, rate or extent of pentose catabolic process to ethanol.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of pentose catabolism to ethanol|up-regulation of pentose catabolic process to ethanol|activation of pentose catabolic process to ethanol|upregulation of pentose catabolism to ethanol|positive regulation of pentose catabolism to ethanol|activation of pentose catabolism to ethanol|up regulation of pentose catabolism to ethanol|up regulation of pentose catabolic process to ethanol|upregulation of pentose catabolic process to ethanol							tt	2012-05-02T04:05:01Z					biological_process											owl:Class	
GO:0120295	biolink:NamedThing	histone serotonyltransferase activity	Catalysis of the reaction: L-glutaminyl-[histone] + serotonin = 5-serotonyl-L-glutamyl-[histone] + NH4(+).	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/20685						krc	2021-01-19T02:13:19Z					molecular_function											owl:Class	
GO:0090065	biolink:NamedThing	regulation of production of siRNA involved in RNA interference	Any process that modulates the frequency, rate or extent of the production of siRNA, the cleavage of double-stranded RNA to form small interfering RNA molecules (siRNAs) of 21-23 nucleotides, in the context of RNA interference.	tmpzr1t_l9r_go_relaxed.owl	regulation of RNA interference, production of siRNA							tb	2009-08-12T11:41:09Z					biological_process											owl:Class	
GO:0044002	biolink:NamedThing	acquisition of nutrients from host	The process that begins with the production and formation of structures and molecules in an organism that are required for the acquisition and utilization of nutrients from its host organism, and the ends with the acquirement of the nutrients. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0051701	biolink:NamedThing	biological process involved in interaction with host	An interaction between two organisms living together in more or less intimate association. The term host is used for the larger (macro) of the two members of a symbiosis; the various forms of symbiosis include parasitism, commensalism and mutualism.	tmpzr1t_l9r_go_relaxed.owl	growth of symbiont in host vacuole|growth of symbiont in host cell|growth of symbiont in host organelle|growth of symbiont in host|interaction with host	https://github.com/geneontology/go-ontology/issues/20191										GO:0044117|GO:0044116|GO:0044121|GO:0044112|GO:0044119|GO:0044125|GO:0044123		biological_process											owl:Class	
GO:0015341	biolink:NamedThing	zinc efflux active transmembrane transporter activity	Enables the transfer of a zinc ion or zinc ions from the inside of the cell to the outside of the cell across a membrane: Zn2+(out) = Zn2+(in). The activity is driven by proton motive force.	tmpzr1t_l9r_go_relaxed.owl	zinc efflux permease activity													molecular_function											owl:Class	
GO:0022883	biolink:NamedThing	zinc efflux transmembrane transporter activity	Enables the transfer of a zinc ion or zinc ions from the inside of the cell to the outside of the cell across a membrane.	tmpzr1t_l9r_go_relaxed.owl	zinc efflux permease activity													molecular_function											owl:Class	
GO:0051254	biolink:NamedThing	positive regulation of RNA metabolic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving RNA.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of RNA metabolic process|activation of RNA metabolic process|positive regulation of RNA metabolism|upregulation of RNA metabolic process|up regulation of RNA metabolic process|stimulation of RNA metabolic process													biological_process											owl:Class	
GO:0060712	biolink:NamedThing	spongiotrophoblast layer development	The process in which the spongiotrophoblast layer of the placenta progresses from its formation to its mature state.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-06-09T03:33:40Z					biological_process											owl:Class	
GO:0062125	biolink:NamedThing	regulation of mitochondrial gene expression	Any process that modulates the frequency, rate or extent of mitochondrial gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA).	tmpzr1t_l9r_go_relaxed.owl								dph	2019-05-30T16:45:04Z					biological_process											owl:Class	
GO:0014898	biolink:NamedThing	cardiac muscle hypertrophy in response to stress	The physiological enlargement or overgrowth of all or part of the heart muscle due to an increase in size (not length) of individual cardiac muscle fibers, without cell division, as a result of a disturbance in organismal or cellular homeostasis.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:2000755	biolink:NamedThing	positive regulation of sphingomyelin catabolic process	Any process that activates or increases the frequency, rate or extent of sphingomyelin catabolic process.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of sphingomyelin degradation|positive regulation of sphingomyelin breakdown|positive regulation of sphingomyelin catabolism							rl	2011-06-16T03:17:35Z					biological_process											owl:Class	
GO:0006757	biolink:NamedThing	ATP generation from ADP	The process of introducing a phosphate group into ADP, adenosine diphosphate, to produce ATP.	tmpzr1t_l9r_go_relaxed.owl	ADP phosphorylation													biological_process											owl:Class	
GO:1990426	biolink:NamedThing	mitotic recombination-dependent replication fork processing	Replication fork processing that includes recombination between DNA near the arrested fork and homologous sequences. Proteins involved in homologous recombination are required for replication restart.	tmpzr1t_l9r_go_relaxed.owl	homologous recombination dependent replication fork recovery|homologous recombination-dependent replication fork processing							mah	2014-07-24T09:42:54Z					biological_process											owl:Class	
GO:1990505	biolink:NamedThing	mitotic DNA replication maintenance of fidelity	Any maintenance of fidelity that is involved in mitotic cell cycle DNA replication.	tmpzr1t_l9r_go_relaxed.owl	maintenance of fidelity involved in mitotic cell cycle DNA replication|maintenance of fidelity involved in mitotic DNA replication							al	2014-10-01T14:09:05Z			GO:1990510		biological_process											owl:Class	
GO:1904412	biolink:NamedThing	regulation of cardiac ventricle development	Any process that modulates the frequency, rate or extent of cardiac ventricle development.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-06-25T19:52:15Z					biological_process											owl:Class	
GO:0007475	biolink:NamedThing	apposition of dorsal and ventral imaginal disc-derived wing surfaces	The coming together of the dorsal and ventral surfaces of the imaginal disc-derived wing during the conversion of a folded single layered wing disc to a flat bilayered wing.	tmpzr1t_l9r_go_relaxed.owl	apposition of dorsal and ventral wing surfaces													biological_process											owl:Class	
GO:0047333	biolink:NamedThing	dihydrostreptomycin-6-phosphate 3'-alpha-kinase activity	Catalysis of the reaction: ATP + dihydrostreptomycin 6-phosphate = ADP + dihydrostreptomycin 3'alpha,6-bisphosphate + 2 H(+).	tmpzr1t_l9r_go_relaxed.owl	dihydrostreptomycin 6-phosphate kinase (phosphorylating)|ATP:dihydrostreptomycin-6-P 3'alpha-phosphotransferase activity|dihydrostreptomycin-6-phosphate 3'alpha-kinase activity|ATP:dihydrostreptomycin-6-phosphate 3'alpha-phosphotransferase activity				RHEA:16281|KEGG_REACTION:R03395|MetaCyc:2.7.1.88-RXN|EC:2.7.1.88									molecular_function											owl:Class	
GO:0034071	biolink:NamedThing	aminoglycoside phosphotransferase activity	Catalysis of the reaction: ATP + aminoglycoside = ADP + phosphoaminoglycoside.	tmpzr1t_l9r_go_relaxed.owl	aminoglycoside kinase activity				EC:2.7.1.-									molecular_function											owl:Class	
GO:0003353	biolink:NamedThing	positive regulation of cilium movement	Any process that increases the rate, frequency, or extent of cilium movement, the directed, self-propelled movement of a cilium.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of flagellar movement|positive regulation of microtubule-based flagellum movement|positive regulation of flagellum movement					Note that we deem cilium and microtubule-based flagellum to be equivalent.		dph	2009-12-03T10:16:10Z			GO:1900174		biological_process											owl:Class	
GO:0003352	biolink:NamedThing	regulation of cilium movement	Any process that modulates the rate, frequency, or extent of cilium movement, the directed, self-propelled movement of a cilium.	tmpzr1t_l9r_go_relaxed.owl	regulation of flagellum movement|regulation of flagellar movement|regulation of microtubule-based flagellum movement					Note that we deem cilium and microtubule-based flagellum to be equivalent.		dph	2009-12-03T10:12:00Z			GO:1900172		biological_process											owl:Class	
GO:0120219	biolink:NamedThing	subapical part of cell	The region of a polarized cell that is just below the apical region. For example, in a polarized epithelial cell, the apical region has an exposed surface and lies opposite to the basal lamina that separates the epithelium from other tissue so the subapical region is further from the exposed surface and closer to the basal lamina.	tmpzr1t_l9r_go_relaxed.owl	subapical region of cell							krc	2019-11-15T17:08:22Z					cellular_component											owl:Class	
GO:1903168	biolink:NamedThing	positive regulation of pyrroline-5-carboxylate reductase activity	Any process that activates or increases the frequency, rate or extent of pyrroline-5-carboxylate reductase activity.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of 1-pyrroline-5-carboxylate reductase activity|upregulation of L-proline:NAD(P)+ 5-oxidoreductase activity|up regulation of L-proline:NAD(P)+ 5-oxidoreductase activity|upregulation of 1-pyrroline-5-carboxylate reductase activity|activation of L-proline:NAD(P)+ 5-oxidoreductase activity|upregulation of NADPH-L-delta1-pyrroline carboxylic acid reductase activity|up-regulation of 1-pyrroline-5-carboxylate reductase activity|upregulation of pyrroline-5-carboxylate reductase activity|upregulation of P5CR activity|up regulation of P5CR activity|up-regulation of NADPH-L-delta1-pyrroline carboxylic acid reductase activity|up regulation of 1-pyrroline-5-carboxylate reductase activity|activation of NADPH-L-delta1-pyrroline carboxylic acid reductase activity|up-regulation of P5CR activity|positive regulation of L-proline oxidase activity|positive regulation of L-proline:NAD(P)+ 5-oxidoreductase activity|up regulation of L-proline oxidase activity|upregulation of L-proline-NAD(P)+ 5-oxidoreductase activity|up regulation of pyrroline-5-carboxylate reductase activity|positive regulation of L-proline-NAD(P)+ 5-oxidoreductase activity|up-regulation of L-proline oxidase activity|up-regulation of L-proline:NAD(P)+ 5-oxidoreductase activity|up-regulation of L-proline-NAD(P)+ 5-oxidoreductase activity|activation of L-proline-NAD(P)+ 5-oxidoreductase activity|activation of P5CR activity|up regulation of NADPH-L-delta1-pyrroline carboxylic acid reductase activity|activation of L-proline oxidase activity|activation of pyrroline-5-carboxylate reductase activity|upregulation of L-proline oxidase activity|up regulation of L-proline-NAD(P)+ 5-oxidoreductase activity|positive regulation of NADPH-L-delta1-pyrroline carboxylic acid reductase activity|up-regulation of pyrroline-5-carboxylate reductase activity|activation of 1-pyrroline-5-carboxylate reductase activity|positive regulation of P5CR activity							bf	2014-07-09T19:51:25Z					biological_process											owl:Class	
GO:1903167	biolink:NamedThing	regulation of pyrroline-5-carboxylate reductase activity	Any process that modulates the frequency, rate or extent of pyrroline-5-carboxylate reductase activity.	tmpzr1t_l9r_go_relaxed.owl	regulation of P5CR activity|regulation of L-proline:NAD(P)+ 5-oxidoreductase activity|regulation of 1-pyrroline-5-carboxylate reductase activity|regulation of NADPH-L-delta1-pyrroline carboxylic acid reductase activity|regulation of L-proline-NAD(P)+ 5-oxidoreductase activity|regulation of L-proline oxidase activity							bf	2014-07-09T19:51:19Z					biological_process											owl:Class	
GO:0044832	biolink:NamedThing	induction by virus of host cytokine production	The process in which a virus increases the frequency, rate or extent of cytokine production in its host organism.	tmpzr1t_l9r_go_relaxed.owl	positive regulation by virus of host cytokine production							jl	2014-02-06T13:04:23Z					biological_process											owl:Class	
GO:0062175	biolink:NamedThing	brexanolone catabolic process	The chemical reactions and pathways resulting in the breakdown of brexanolone.	tmpzr1t_l9r_go_relaxed.owl	allopregnanolone catabolism|allotetrahydroprogesterone breakdown|allopregnanolone breakdown|allotetrahydroprogesterone catabolic process|allotetrahydroprogesterone degradation|allotetrahydroprogesterone catabolism|brexanolone breakdown|allopregnanolone catabolic process|allopregnanolone degradation|brexanolone degradation|brexanolone catabolism							dph	2019-11-18T19:57:46Z					biological_process											owl:Class	
GO:0005599	biolink:NamedThing	collagen type X trimer	A collagen homotrimer of alpha1(X) chains; type X collagen triple helices form hexagonal networks (sheets).	tmpzr1t_l9r_go_relaxed.owl						Collagen X trimers have been observed to form hexagonal lattices in vitro, but in vivo they have been found in a fibril associated form (PMID:19693541).								cellular_component											owl:Class	
GO:0014056	biolink:NamedThing	regulation of acetylcholine secretion, neurotransmission	Any process that modulates the frequency, rate or extent of the regulated release of acetylcholine.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0052756	biolink:NamedThing	chitobiose phosphorylase activity	Catalysis of the reaction: chitobiose + phosphate = N-acetyl-D-glucosamine + N-acetyl-alpha-D-glucosamine 1-phosphate. This reaction is the phosphorolysis of chitobiose, (GlcNAc)2, a dimer of beta-(1->4) linked glucosamine units.	tmpzr1t_l9r_go_relaxed.owl								ai	2011-09-27T04:04:53Z					molecular_function											owl:Class	
GO:0021664	biolink:NamedThing	rhombomere 5 morphogenesis	The process in which the anatomical structures of rhombomere 5 are generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0038094	biolink:NamedThing	Fc-gamma receptor signaling pathway	A series of molecular signals initiated by the binding of the Fc portion of immunoglobulin G (IgG) to an Fc-gamma receptor on the surface of a signal-receiving cell, and ending with regulation of a downstream cellular process, e.g. transcription. The Fc portion of an immunoglobulin is its C-terminal constant region.	tmpzr1t_l9r_go_relaxed.owl	Fc-gamma receptor signalling pathway							bf	2012-02-16T05:22:46Z					biological_process											owl:Class	
GO:0038093	biolink:NamedThing	Fc receptor signaling pathway	A series of molecular signals initiated by the binding of the Fc portion of an immunoglobulin to an Fc receptor on the surface of a signal-receiving cell, and ending with regulation of a downstream cellular process, e.g. transcription. The Fc portion of an immunoglobulin is its C-terminal constant region.	tmpzr1t_l9r_go_relaxed.owl	Fc receptor signalling pathway							bf	2012-02-16T05:11:30Z					biological_process											owl:Class	
GO:0043171	biolink:NamedThing	peptide catabolic process	The chemical reactions and pathways resulting in the breakdown of peptides, compounds of 2 or more (but usually less than 100) amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another.	tmpzr1t_l9r_go_relaxed.owl	peptide catabolism|peptide degradation|peptide breakdown													biological_process											owl:Class	
GO:0046533	biolink:NamedThing	negative regulation of photoreceptor cell differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of photoreceptor cell differentiation. An example of this process is found in Drosophila melanogaster.	tmpzr1t_l9r_go_relaxed.owl	down regulation of photoreceptor differentiation|down-regulation of photoreceptor differentiation|inhibition of photoreceptor cell differentiation|down regulation of photoreceptor cell differentiation|downregulation of photoreceptor cell differentiation|inhibition of photoreceptor differentiation|downregulation of photoreceptor differentiation|down-regulation of photoreceptor cell differentiation|negative regulation of photoreceptor differentiation											GO:0045674		biological_process											owl:Class	
GO:0044403	biolink:NamedThing	biological process involved in symbiotic interaction	A process carried out by gene products in an organism that enable the organism to engage in a symbiotic relationship, a more or less intimate association, with another organism. The various forms of symbiosis include parasitism, in which the association is disadvantageous or destructive to one of the organisms; mutualism, in which the association is advantageous, or often necessary to one or both and not harmful to either; and commensalism, in which one member of the association benefits while the other is not affected. However, mutualism, parasitism, and commensalism are often not discrete categories of interactions and should rather be perceived as a continuum of interaction ranging from parasitism to mutualism. In fact, the direction of a symbiotic interaction can change during the lifetime of the symbionts due to developmental changes as well as changes in the biotic/abiotic environment in which the interaction occurs. Microscopic symbionts are often referred to as endosymbionts.	tmpzr1t_l9r_go_relaxed.owl	parasitism|symbiosis|symbiotic interaction between species|symbiotic interaction between host and organism|symbiotic interaction|host-pathogen interaction|symbiosis, encompassing mutualism through parasitism|symbiotic interaction between organisms|symbiotic process|commensalism	https://github.com/geneontology/go-ontology/issues/20191|https://github.com/geneontology/go-ontology/issues/14807										GO:0043298|GO:0072519|GO:0085031|GO:0044404		biological_process											owl:Class	
GO:1901826	biolink:NamedThing	zeaxanthin catabolic process	The chemical reactions and pathways resulting in the breakdown of zeaxanthin.	tmpzr1t_l9r_go_relaxed.owl	zeaxanthin degradation|zeaxanthin breakdown|zeaxanthin catabolism							yaf	2013-01-22T11:37:00Z					biological_process											owl:Class	
GO:1901825	biolink:NamedThing	zeaxanthin metabolic process	The chemical reactions and pathways involving zeaxanthin.	tmpzr1t_l9r_go_relaxed.owl	zeaxanthin metabolism							yaf	2013-01-22T11:36:55Z					biological_process											owl:Class	
GO:0006434	biolink:NamedThing	seryl-tRNA aminoacylation	The process of coupling serine to seryl-tRNA, catalyzed by seryl-tRNA synthetase. The seryl-tRNA synthetase is a  class-II synthetase. The activated amino acid is transferred to the 3'-OH group of a serine-accetping tRNA.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1904872	biolink:NamedThing	regulation of telomerase RNA localization to Cajal body	Any process that modulates the frequency, rate or extent of telomerase RNA localization to Cajal body.	tmpzr1t_l9r_go_relaxed.owl								nc	2015-12-18T11:28:20Z					biological_process											owl:Class	
GO:0006560	biolink:NamedThing	proline metabolic process	The chemical reactions and pathways involving proline (pyrrolidine-2-carboxylic acid), a chiral, cyclic, nonessential alpha-amino acid found in peptide linkage in proteins.	tmpzr1t_l9r_go_relaxed.owl	proline metabolism													biological_process											owl:Class	
GO:0075320	biolink:NamedThing	negative regulation of ascus development	Any process that stops, prevents, or reduces the frequency, rate or extent of ascus development, a saclike structure produced by fungi of the phylum Ascomycota (sac fungi) in which sexually produced spores (ascospores), usually four or eight in number, are formed.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0097172	biolink:NamedThing	N-acetylmuramic acid metabolic process	The chemical reactions and pathways involving N-acetylmuramic acid (MurNAc), a monosaccharide derivative of N-acetylglucosamine.	tmpzr1t_l9r_go_relaxed.owl	N-acetylmuramate metabolic process|N-acetylmuramate metabolism|N-acetylmuramic acid metabolism							pr	2011-10-07T12:45:24Z					biological_process											owl:Class	
GO:0070116	biolink:NamedThing	organellar chromatophore thylakoid	A thylakoid located in an organellar chromatophore.	tmpzr1t_l9r_go_relaxed.owl	Paulinella-type chromatophore thylakoid													cellular_component											owl:Class	
GO:0039506	biolink:NamedThing	modulation by virus of host molecular function	The process in which a virus effects a change in the function of a host protein via a direct interaction.	tmpzr1t_l9r_go_relaxed.owl	modification by virus of host protein function							bf	2011-06-02T02:38:42Z					biological_process											owl:Class	
GO:0010226	biolink:NamedThing	response to lithium ion	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lithium (Li+) ion stimulus.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0072285	biolink:NamedThing	mesenchymal to epithelial transition involved in metanephric renal vesicle formation	A transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the metanephric renal vesicle.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-04-01T03:43:31Z					biological_process											owl:Class	
GO:0072036	biolink:NamedThing	mesenchymal to epithelial transition involved in renal vesicle formation	A transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the renal vesicle.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-01-25T03:04:24Z					biological_process											owl:Class	
GO:0070105	biolink:NamedThing	positive regulation of interleukin-6-mediated signaling pathway	Any process that increases the rate, frequency or extent of the series of molecular events generated as a consequence of interleukin-6 binding to a cell surface receptor.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of IL-6-mediated signaling pathway|positive regulation of interleukin-6-mediated signalling pathway													biological_process											owl:Class	
GO:0005501	biolink:NamedThing	retinoid binding	Binding to a retinoid, a class of isoprenoids that contain or are derived from four prenyl groups linked head-to-tail. Retinoids include retinol and retinal and structurally similar natural derivatives or synthetic compounds, but need not have vitamin A activity.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-2465934|Reactome:R-HSA-2465938|Reactome:R-HSA-2454113|Reactome:R-HSA-2464809									molecular_function											owl:Class	
GO:0019840	biolink:NamedThing	isoprenoid binding	Binding to an isoprenoid compound, isoprene (2-methylbuta-1,3-diene) or compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1902798	biolink:NamedThing	positive regulation of snoRNA processing	Any process that activates or increases the frequency, rate or extent of snoRNA processing.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of snoRNA processing|upregulation of snoRNA processing|up regulation of snoRNA processing|activation of snoRNA processing							mah	2014-03-24T12:47:20Z					biological_process											owl:Class	
GO:0033603	biolink:NamedThing	positive regulation of dopamine secretion	Any process that activates or increases the frequency, rate or extent of the regulated release of dopamine.	tmpzr1t_l9r_go_relaxed.owl	stimulation of dopamine secretion|upregulation of dopamine secretion|activation of dopamine secretion|up-regulation of dopamine secretion|up regulation of dopamine secretion													biological_process											owl:Class	
GO:0045690	biolink:NamedThing	positive regulation of antipodal cell differentiation	Any process that activates or increases the frequency, rate or extent of antipodal cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	stimulation of antipodal cell differentiation|activation of antipodal cell differentiation|up regulation of antipodal cell differentiation|up-regulation of antipodal cell differentiation|upregulation of antipodal cell differentiation													biological_process											owl:Class	
GO:0045688	biolink:NamedThing	regulation of antipodal cell differentiation	Any process that modulates the frequency, rate or extent of antipodal cell differentiation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0017008	biolink:NamedThing	protein-phycobiliviolin linkage	The linkage of the chromophore phycobiliviolin to phycoerythrocyanin.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0258									biological_process											owl:Class	
GO:0033033	biolink:NamedThing	negative regulation of myeloid cell apoptotic process	Any process that stops, prevents, or reduces the frequency, rate, or extent of a myeloid cell apoptotic process.	tmpzr1t_l9r_go_relaxed.owl	down regulation of myeloid cell apoptosis|negative regulation of myeloid cell apoptosis|down-regulation of myeloid cell apoptosis|downregulation of myeloid cell apoptosis|inhibition of myeloid cell apoptosis													biological_process											owl:Class	
GO:0060779	biolink:NamedThing	secondary leaflet morphogenesis	The process in which the secondary leaflet attains its shape. A secondary leaflet develops by branching or division of a primary leaflet.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-07-25T07:19:02Z					biological_process											owl:Class	
GO:0060794	biolink:NamedThing	leaflet morphogenesis	The process in which the anatomical structures of the leaflet are generated and organized.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-08-04T02:58:14Z					biological_process											owl:Class	
GO:0002809	biolink:NamedThing	negative regulation of antibacterial peptide biosynthetic process	Any process that stops, prevents, or reduces the frequency, rate, or extent of antibacterial peptide biosynthesis.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of antibacterial peptide biosynthetic process|downregulation of antibacterial peptide biosynthetic process|inhibition of antibacterial peptide biosynthetic process|down regulation of antibacterial peptide biosynthetic process													biological_process											owl:Class	
GO:0002806	biolink:NamedThing	negative regulation of antimicrobial peptide biosynthetic process	Any process that stops, prevents, or reduces the frequency, rate, or extent of antimicrobial peptide biosynthesis.	tmpzr1t_l9r_go_relaxed.owl	inhibition of antimicrobial peptide biosynthetic process|down regulation of antimicrobial peptide biosynthetic process|down-regulation of antimicrobial peptide biosynthetic process|downregulation of antimicrobial peptide biosynthetic process													biological_process											owl:Class	
GO:0009173	biolink:NamedThing	pyrimidine ribonucleoside monophosphate metabolic process	The chemical reactions and pathways involving pyrimidine ribonucleoside monophosphate, a compound consisting of a pyrimidine base linked to a ribose sugar esterified with phosphate on the sugar.	tmpzr1t_l9r_go_relaxed.owl	pyrimidine ribonucleoside monophosphate metabolism													biological_process											owl:Class	
GO:0097106	biolink:NamedThing	postsynaptic density organization	A process that results in the assembly, arrangement of constituent parts, or disassembly of a postsynaptic density, a region that lies adjacent to the cytoplasmic face of the postsynaptic membrane at excitatory synapse.	tmpzr1t_l9r_go_relaxed.owl	post-synaptic density organization|post synaptic density organization|PSD organization|postsynaptic density organisation							pr	2011-07-27T05:17:12Z					biological_process											owl:Class	
GO:1902309	biolink:NamedThing	negative regulation of peptidyl-serine dephosphorylation	Any process that stops, prevents or reduces the frequency, rate or extent of peptidyl-serine dephosphorylation.	tmpzr1t_l9r_go_relaxed.owl	downregulation of peptidyl-serine dephosphorylation|down regulation of peptidyl-serine dephosphorylation|inhibition of peptidyl-serine dephosphorylation|down-regulation of peptidyl-serine dephosphorylation							rl	2013-07-19T10:35:07Z					biological_process											owl:Class	
GO:0006393	biolink:NamedThing	termination of mitochondrial transcription	The process in which the synthesis of an RNA molecule using a mitochondrial DNA template is completed.	tmpzr1t_l9r_go_relaxed.owl	RNA transcription termination from mitochondrial promoter|mitochondrial transcription termination													biological_process											owl:Class	
GO:0006353	biolink:NamedThing	DNA-templated transcription, termination	The cellular process that completes DNA-templated transcription; the formation of phosphodiester bonds ceases, the RNA-DNA hybrid dissociates, and RNA polymerase releases the DNA.	tmpzr1t_l9r_go_relaxed.owl	termination of DNA-dependent transcription|DNA-dependent transcription, termination|transcription termination factor activity|transcription termination from bacterial-type RNA polymerase promoter|transcription termination, DNA-dependent|transcriptional complex disassembly|termination of transcription, DNA-dependent											GO:0001125		biological_process											owl:Class	
GO:0071816	biolink:NamedThing	tail-anchored membrane protein insertion into ER membrane	A process of protein insertion into the endoplasmic reticulum (ER) membrane in which a tail-anchored (TA) transmembrane protein is incorporated into an endoplasmic reticulum (ER) membrane. TA transmembrane protein, also named type II transmembrane proteins, contain a single C- terminal transmembrane region.	tmpzr1t_l9r_go_relaxed.owl	type II transmembrane protein insertion into ER membrane|tail-anchored membrane protein insertion into endoplasmic reticulum membrane|protein insertion of tail-anchored membrane proteins into ER membrane							mah	2010-09-06T04:55:16Z					biological_process											owl:Class	
GO:0045048	biolink:NamedThing	protein insertion into ER membrane	The process that results in incorporation of a protein into an endoplasmic reticulum (ER) membrane. It depends on specific topogenic sequences of amino acids that ensure that a protein acquires the proper orientation during its insertion into the ER membrane.	tmpzr1t_l9r_go_relaxed.owl	integral ER membrane protein positioning|integral ER membrane protein localization|localization of protein in ER membrane|protein insertion into endoplasmic reticulum membrane|protein-endoplasmic reticulum insertion|protein-ER insertion|positioning of protein in ER membrane													biological_process											owl:Class	
GO:0043278	biolink:NamedThing	response to morphine	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a morphine stimulus. Morphine is an opioid alkaloid, isolated from opium, with a complex ring structure.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0014072	biolink:NamedThing	response to isoquinoline alkaloid	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an isoquinoline alkaloid stimulus. An isoquinoline alkaloid is any member of a group of compounds with the heterocyclic ring structure of benzo(c)pyridine which is a structure characteristic of the group of opium alkaloids.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0090653	biolink:NamedThing	apical recycling endosome	Tubulo-vesicular structure located in the apical cytoplasm that participates in apical cargo recycling in polarized epithelial cells.	tmpzr1t_l9r_go_relaxed.owl								tb	2015-07-01T15:46:19Z					cellular_component											owl:Class	
GO:0071986	biolink:NamedThing	Ragulator complex	A vacuolar membrane-anchored guanine nucleotide exchange factor (GEF) complex for the Rag GTPases (Gtr1-Gtr2 GTPase complex GO:1990131) in TORC1 signalling pathway. In human, Ragulator is comprised of the membrane anchor subunit LAMTOR1 (Meh1p in S. cerevisiae, Lam1 in S. pombe), a GEF subunit LAMTOR2 ( Slm4 in S. cerevisiae , Lam2 in S. pombe ) , LAMTOR3 (no S. cerevisiae ortholog identified, Lam3 in S. pombe) , LAMTOR4 (no S. cerevisiae ortholog identified, Lam4 in S. pombe), and LAMTOR5 (no S. cerevisiae or S. pombe ortholog identified).	tmpzr1t_l9r_go_relaxed.owl	EGO-GSE complex|EGO complex|MAPKSP1/ROBLD3/C11orf59 complex|GTPase-containing complex for Gap1p sorting in the endosome|Rag GEF|GSE complex	https://github.com/geneontology/go-ontology/issues/20822|https://github.com/geneontology/go-ontology/issues/21777						mah	2010-10-22T02:42:13Z			GO:0034449|GO:0034448		cellular_component											owl:Class	
GO:0008516	biolink:NamedThing	hexose uniporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: hexose(out) = hexose(in).	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0015149	biolink:NamedThing	hexose transmembrane transporter activity	Enables the transfer of a hexose sugar, a monosaccharide with 6 carbon atoms, from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-5638222|Reactome:R-HSA-189242									molecular_function											owl:Class	
GO:0032061	biolink:NamedThing	negative regulation of translation in response to osmotic stress	Any process that stops, prevents or reduces the rate of translation as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell.	tmpzr1t_l9r_go_relaxed.owl	downregulation of translation in response to osmotic stress|down regulation of translation in response to osmotic stress|down-regulation of translation in response to osmotic stress|inhibition of translation in response to osmotic stress													biological_process											owl:Class	
GO:0043557	biolink:NamedThing	regulation of translation in response to osmotic stress	Any process that modulates the frequency, rate or extent of the frequency, rate or extent of translation as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0032687	biolink:NamedThing	negative regulation of interferon-alpha production	Any process that stops, prevents, or reduces the frequency, rate, or extent of interferon-alpha production.	tmpzr1t_l9r_go_relaxed.owl	down regulation of interferon-alpha production|inhibition of interferon-alpha production|down-regulation of interferon-alpha production|negative regulation of interferon-alpha secretion|downregulation of interferon-alpha production|negative regulation of interferon-alpha biosynthetic process											GO:0045355|GO:1902740		biological_process											owl:Class	
GO:0032647	biolink:NamedThing	regulation of interferon-alpha production	Any process that modulates the frequency, rate, or extent of interferon-alpha production.	tmpzr1t_l9r_go_relaxed.owl	regulation of interferon-alpha secretion|regulation of interferon-alpha biosynthetic process											GO:0045354|GO:1902739		biological_process											owl:Class	
GO:0042120	biolink:NamedThing	alginic acid metabolic process	The chemical reactions and pathways involving alginic acid, a hydrophilic polysaccharide occurring in, for example, the cell walls of brown algae (brown seaweeds).	tmpzr1t_l9r_go_relaxed.owl	alginate metabolism|alginic acid metabolism|alginate metabolic process													biological_process											owl:Class	
GO:0071267	biolink:NamedThing	L-methionine salvage	Any process that generates L-methionine from derivatives of it, without de novo synthesis.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-12-09T04:36:49Z					biological_process											owl:Class	
GO:0043102	biolink:NamedThing	amino acid salvage	Any process which produces an amino acid from derivatives of it, without de novo synthesis.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0015009	biolink:NamedThing	corrin metabolic process	The chemical reactions and pathways involving corrin, C19H22N4, the fundamental heterocyclic skeleton of the corrinoids. It consists of four reduced pyrrole rings joined into a macrocyclic ring. Corrin is the core of the vitamin B12 molecule.	tmpzr1t_l9r_go_relaxed.owl	corrin metabolism													biological_process											owl:Class	
GO:0033013	biolink:NamedThing	tetrapyrrole metabolic process	The chemical reactions and pathways involving tetrapyrroles, natural pigments containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next.	tmpzr1t_l9r_go_relaxed.owl	tetrapyrrole metabolism													biological_process											owl:Class	
GO:0018244	biolink:NamedThing	protein N-linked glycosylation via tryptophan	The glycosylation of protein via peptidyl-tryptophan, 1'-glycosyl-L-tryptophan; results in the formation of an (S)-2-amino-3-(1-D-mannopyranosyloxy-1H-indol-3-yl)propanoic acid residue.	tmpzr1t_l9r_go_relaxed.owl	protein amino acid N-linked glycosylation via tryptophan				RESID:AA0156									biological_process											owl:Class	
GO:0006487	biolink:NamedThing	protein N-linked glycosylation	A protein glycosylation process in which a carbohydrate or carbohydrate derivative unit is added to a protein via the N4 atom of peptidyl-asparagine, the omega-N of arginine, or the N1' atom peptidyl-tryptophan.	tmpzr1t_l9r_go_relaxed.owl	protein amino acid N-linked glycosylation|N-glycan biosynthesis|N-glycan metabolism				RESID:AA0151|RESID:AA0327|RESID:AA0156									biological_process											owl:Class	
GO:1901528	biolink:NamedThing	hydrogen peroxide mediated signaling pathway involved in stomatal movement	Any hydrogen peroxide mediated signaling pathway that is involved in stomatal movement.	tmpzr1t_l9r_go_relaxed.owl	H2O2 mediated signaling pathway involved in stomatal movement|hydrogen peroxide mediated signalling pathway involved in stomatal movement							tb	2012-10-23T23:15:25Z					biological_process											owl:Class	
GO:0071588	biolink:NamedThing	hydrogen peroxide mediated signaling pathway	A series of molecular signals mediated by the detection of hydrogen peroxide (H2O2).	tmpzr1t_l9r_go_relaxed.owl	hydrogen peroxide mediated signalling pathway|H2O2 mediated signaling pathway							mah	2010-01-29T11:18:58Z					biological_process											owl:Class	
GO:1990170	biolink:NamedThing	stress response to cadmium ion	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis caused by a cadmium ion stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to cadmium ion stress|stress response to cadmium|response to cadmium toxicity							pr	2013-08-14T12:55:45Z					biological_process											owl:Class	
GO:0046148	biolink:NamedThing	pigment biosynthetic process	The chemical reactions and pathways resulting in the formation of a pigment, any general or particular coloring matter in living organisms, e.g. melanin.	tmpzr1t_l9r_go_relaxed.owl	pigment formation|pigment synthesis|pigment biosynthesis|pigment anabolism													biological_process											owl:Class	
GO:0048685	biolink:NamedThing	negative regulation of collateral sprouting of intact axon in response to injury	Any process that stops, prevents, or reduces the frequency, rate or extent of collateral sprouting of an intact axon as a result of injury to an axon.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of collateral sprouting of intact axon in response to injury|down regulation of collateral sprouting of intact axon in response to injury|downregulation of collateral sprouting of intact axon in response to injury|inhibition of collateral sprouting of intact axon in response to injury													biological_process											owl:Class	
GO:0008466	biolink:NamedThing	glycogenin glucosyltransferase activity	Catalysis of the reaction: UDP-glucose + glycogenin = UDP + glucosylglycogenin.	tmpzr1t_l9r_go_relaxed.owl	glycogenin activity|1,4alpha-glucan-protein synthase (UDP-forming) activity|priming glucosyltransferase activity|alpha-1,4-glucan-protein synthase (UDP-forming) activity|UDP-glucose:glycogenin glucosyltransferase activity|UDP-alpha-D-glucose:glycogenin alpha-D-glucosyltransferase activity				RHEA:23360|Reactome:R-HSA-3322014|Reactome:R-HSA-3814838|MetaCyc:GLYCOGENIN-GLUCOSYLTRANSFERASE-RXN|Reactome:R-HSA-3322025|Reactome:R-HSA-3322019|EC:2.4.1.186|Reactome:R-HSA-3322003							GO:0047210		molecular_function											owl:Class	
GO:1901200	biolink:NamedThing	negative regulation of calcium ion transport into cytosol involved in cellular response to salt stress	Any negative regulation of calcium ion transport into cytosol that is involved in cellular response to salt stress.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of calcium ion transport into cytosol involved in cellular response to ionic osmotic stress|negative regulation of calcium ion transport into cytosol involved in cellular salinity response							al	2012-07-27T11:11:09Z					biological_process											owl:Class	
GO:0010523	biolink:NamedThing	negative regulation of calcium ion transport into cytosol	Any process that decreases the rate of the directed movement of calcium ions into the cytosol of a cell. The cytosol is that part of the cytoplasm that does not contain membranous or particulate subcellular components.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0120076	biolink:NamedThing	negative regulation of endocardial cushion cell differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of endocardial cushion cell differentiation.	tmpzr1t_l9r_go_relaxed.owl								krc	2017-06-26T23:37:23Z					biological_process											owl:Class	
GO:1905208	biolink:NamedThing	negative regulation of cardiocyte differentiation	Any process that stops, prevents or reduces the frequency, rate or extent of cardiocyte differentiation.	tmpzr1t_l9r_go_relaxed.owl	downregulation of cardiac cell differentiation|down-regulation of cardiocyte differentiation|inhibition of heart cell differentiation|inhibition of cardiac cell differentiation|down regulation of heart cell differentiation|down-regulation of cardiac cell differentiation|down-regulation of heart cell differentiation|down regulation of cardiac cell differentiation|down regulation of cardiocyte differentiation|inhibition of cardiocyte differentiation|downregulation of heart cell differentiation|downregulation of cardiocyte differentiation|negative regulation of cardiac cell differentiation|negative regulation of heart cell differentiation							bc	2016-06-02T07:20:09Z					biological_process											owl:Class	
GO:0060753	biolink:NamedThing	regulation of mast cell chemotaxis	Any process that modulates the rate, frequency or extent of mast cell chemotaxis. Mast cell chemotaxis is the movement of a mast cell in response to an external stimulus.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-06-22T02:36:06Z					biological_process											owl:Class	
GO:1901941	biolink:NamedThing	(+)-epi-alpha-bisabolol metabolic process	The chemical reactions and pathways involving (+)-epi-alpha-bisabolol.	tmpzr1t_l9r_go_relaxed.owl	(+)-epi-alpha-bisabolol metabolism							ms	2013-02-18T14:55:36Z					biological_process											owl:Class	
GO:0006714	biolink:NamedThing	sesquiterpenoid metabolic process	The chemical reactions and pathways involving sesquiterpenoid compounds, terpenoids with three isoprene units.	tmpzr1t_l9r_go_relaxed.owl	sesquiterpenoid metabolism													biological_process											owl:Class	
GO:0015265	biolink:NamedThing	urea channel activity	Enables the facilitated diffusion of urea (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-507873|Reactome:R-HSA-507875									molecular_function											owl:Class	
GO:0015204	biolink:NamedThing	urea transmembrane transporter activity	Enables the transfer of urea from one side of a membrane to the other. Urea is the water soluble compound H2N-CO-NH2.	tmpzr1t_l9r_go_relaxed.owl	urea transporter activity				Reactome:R-HSA-444126|RHEA:32799							GO:0015287		molecular_function											owl:Class	
GO:0072290	biolink:NamedThing	epithelial cell migration involved in metanephric nephron tubule morphogenesis	The orderly movement of epithelial cells within a renal tubule that contributes to metanephric nephron tubule morphogenesis.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-04-09T03:52:29Z					biological_process											owl:Class	
GO:0030206	biolink:NamedThing	chondroitin sulfate biosynthetic process	The chemical reactions and pathways resulting in the formation of chondroitin sulfate, any member of a group of 10-60 kDa glycosaminoglycans, widely distributed in cartilage and other mammalian connective tissues, the repeat units of which consist of beta-(1,4)-linked D-glucuronyl beta-(1,3)-N-acetyl-D-galactosamine sulfate.	tmpzr1t_l9r_go_relaxed.owl	chondroitin sulphate biosynthesis|chondroitin sulfate synthesis|chondroitin sulfate anabolism|chondroitin sulfate formation|chondroitin sulfate biosynthesis|chondroitin sulphate biosynthetic process													biological_process											owl:Class	
GO:0006024	biolink:NamedThing	glycosaminoglycan biosynthetic process	The chemical reactions and pathways resulting in the formation of glycosaminoglycans, any of a group of polysaccharides that contain amino sugars.	tmpzr1t_l9r_go_relaxed.owl	glycosaminoglycan biosynthesis|glycosaminoglycan anabolism|glycosaminoglycan formation|glycosaminoglycan synthesis													biological_process											owl:Class	
GO:0042390	biolink:NamedThing	gibberellic acid mediated signaling pathway, G-alpha-independent	A series of molecular signals mediated by the detection of gibberellic acid and not dependent on the coupling of the alpha subunit of G proteins to the hormone receptors.	tmpzr1t_l9r_go_relaxed.owl	gibberellic acid mediated signalling, G-alpha-independent													biological_process											owl:Class	
GO:1905827	biolink:NamedThing	positive regulation of selenocysteine metabolic process	Any process that activates or increases the frequency, rate or extent of selenocysteine metabolic process.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of selenocysteine metabolism|up regulation of selenocysteine metabolic process|upregulation of selenocysteine metabolic process|positive regulation of selenocysteine metabolism|up regulation of selenocysteine metabolism|activation of selenocysteine metabolic process|upregulation of selenocysteine metabolism|up-regulation of selenocysteine metabolic process|activation of selenocysteine metabolism							sl	2017-01-16T19:01:50Z					biological_process											owl:Class	
GO:0060633	biolink:NamedThing	negative regulation of transcription initiation from RNA polymerase II promoter	Any process that decreases the rate, frequency or extent of a process involved in starting transcription from an RNA polymerase II promoter.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-05-18T03:11:26Z					biological_process											owl:Class	
GO:0042945	biolink:NamedThing	D-serine transmembrane transporter activity	Enables the transfer of D-serine from one side of a membrane to the other. D-serine is the D-enantiomer of 2-amino-3-hydroxypropanoic acid.	tmpzr1t_l9r_go_relaxed.owl	D-serine permease activity|D-serine transporter activity													molecular_function											owl:Class	
GO:0042943	biolink:NamedThing	D-amino acid transmembrane transporter activity	Enables the transfer of D-amino acids from one side of a membrane to the other. D-amino acids are the D-enantiomers of amino acids.	tmpzr1t_l9r_go_relaxed.owl	D-amino acid transporter activity													molecular_function											owl:Class	
GO:1903233	biolink:NamedThing	regulation of calcium ion-dependent exocytosis of neurotransmitter	Any process that modulates the frequency, rate or extent of calcium ion-dependent exocytosis of neurotransmitter.	tmpzr1t_l9r_go_relaxed.owl						An example of this is Rab3gap1 in mouse (Q80UJ7) in PMID:16782817 (IMP)		pad	2014-07-31T11:54:33Z					biological_process											owl:Class	
GO:0009357	biolink:NamedThing	protein-N(PI)-phosphohistidine-sugar phosphotransferase complex	An enzyme complex that catalyzes the transfer of a phosphate from protein N(PI)-phosphohistidine to a sugar molecule. It is enzyme II of the phosphotransferase system.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0010005	biolink:NamedThing	cortical microtubule, transverse to long axis	Arrays of microtubules underlying and connected to the plasma membrane, in the cortical cytosol, oriented mainly with their axes transverse to the long axis of the cell (and root in plants). In plants it influences the direction of cellulose microfibril deposition.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0055028	biolink:NamedThing	cortical microtubule	Arrays of microtubules underlying and connected to the plasma membrane in the cortical cytosol.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0015715	biolink:NamedThing	nucleotide-sulfate transport	The directed movement of nucleotide sulfate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	nucleotide-sulphate transport													biological_process											owl:Class	
GO:0045962	biolink:NamedThing	positive regulation of development, heterochronic	Any process that modulates the consistent predetermined time point at which an integrated living unit or organism progresses from an initial condition to a later condition and increases the rate at which this time point is reached.	tmpzr1t_l9r_go_relaxed.owl	stimulation of development, heterochronic|activation of development, heterochronic|upregulation of development, heterochronic|up regulation of development, heterochronic|up-regulation of development, heterochronic													biological_process											owl:Class	
GO:0040034	biolink:NamedThing	regulation of development, heterochronic	Any process that modulates the consistent predetermined time point at which an integrated living unit or organism progresses from an initial condition to a later condition and the rate at which this time point is reached.	tmpzr1t_l9r_go_relaxed.owl	developmental timing|temporal regulation of development|heterochronic regulation of development													biological_process											owl:Class	
GO:1901150	biolink:NamedThing	vistamycin metabolic process	The chemical reactions and pathways involving vistamycin.	tmpzr1t_l9r_go_relaxed.owl	ribostamycin metabolic process|vistamycin metabolism|ribostamycin metabolism							yaf	2012-07-17T04:26:45Z					biological_process											owl:Class	
GO:0015548	biolink:NamedThing	organomercurial transmembrane transporter activity	Enables the transfer of organomercurial compounds from one side of a membrane to the other. Organomercurial substances are any organic compound containing a mercury atom.	tmpzr1t_l9r_go_relaxed.owl	organomercurial transporter activity|carbonyl cyanide m-chlorophenylhydrazone/nalidixic acid/organomercurials:hydrogen antiporter activity													molecular_function											owl:Class	
GO:0009007	biolink:NamedThing	site-specific DNA-methyltransferase (adenine-specific) activity	Catalysis of the reaction: S-adenosyl-L-methionine + DNA adenine = S-adenosyl-L-homocysteine + DNA 6-methylaminopurine.	tmpzr1t_l9r_go_relaxed.owl	DNA adenine methylase|N-6 adenine-specific DNA methylase activity|EcoRI methylase|modification methylase activity|restriction-modification system activity				MetaCyc:2.1.1.72-RXN|EC:2.1.1.72|RHEA:15197									molecular_function											owl:Class	
GO:1905035	biolink:NamedThing	negative regulation of antifungal innate immune response	Any process that stops, prevents or reduces the frequency, rate or extent of an antifungal innate immune response.	tmpzr1t_l9r_go_relaxed.owl	inhibition of antifungal innate immune response|down regulation of antifungal innate immune response|downregulation of antifungal innate immune response|down-regulation of antifungal innate immune response							dph	2016-03-07T20:08:05Z					biological_process											owl:Class	
GO:2000244	biolink:NamedThing	regulation of FtsZ-dependent cytokinesis	Any process that modulates the frequency, rate or extent of FtsZ-dependent cytokinesis.	tmpzr1t_l9r_go_relaxed.owl	regulation of prokaryotic fission|regulation of prokaryote-type cytokinesis							mah	2010-11-10T02:46:36Z					biological_process											owl:Class	
GO:0010218	biolink:NamedThing	response to far red light	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of far red light stimulus. Far red light is electromagnetic radiation of wavelength 700-800nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reversed by exposure to far red light. During the initial phase the phytochrome molecule is only present in the red light absorbing form, but on absorption of red light it changes to a far red light absorbing form, triggering progress through development. An immediate short period of exposure to far red light entirely returns the pigment to its initial state and prevents triggering of the developmental process. A thirty minute break between red and subsequent far red light exposure renders the red light effect irreversible, and development then occurs regardless of whether far red light exposure subsequently occurs.	tmpzr1t_l9r_go_relaxed.owl	response to far red light stimulus													biological_process											owl:Class	
GO:0009157	biolink:NamedThing	deoxyribonucleoside monophosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of a deoxyribonucleoside monophosphate, a compound consisting of a nucleobase linked to a deoxyribose sugar esterified with phosphate on the sugar.	tmpzr1t_l9r_go_relaxed.owl	deoxyribonucleoside monophosphate synthesis|deoxyribonucleoside monophosphate anabolism|deoxyribonucleoside monophosphate biosynthesis|deoxyribonucleoside monophosphate formation													biological_process											owl:Class	
GO:0009162	biolink:NamedThing	deoxyribonucleoside monophosphate metabolic process	The chemical reactions and pathways involving a deoxyribonucleoside monophosphate, a compound consisting of a nucleobase linked to a deoxyribose sugar esterified with phosphate on the sugar.	tmpzr1t_l9r_go_relaxed.owl	deoxyribonucleoside monophosphate metabolism													biological_process											owl:Class	
GO:0000768	biolink:NamedThing	syncytium formation by plasma membrane fusion	The formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells.	tmpzr1t_l9r_go_relaxed.owl	cell fusion													biological_process											owl:Class	
GO:0006949	biolink:NamedThing	syncytium formation	The formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane. Syncytia are normally derived from single cells that fuse or fail to complete cell division.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0046807	biolink:NamedThing	viral scaffold assembly and maintenance	The assembly and maintenance of the viral scaffold around which the viral capsid is constructed.	tmpzr1t_l9r_go_relaxed.owl						See also the cellular component term 'viral scaffold ; GO:0046806'.								biological_process											owl:Class	
GO:0060827	biolink:NamedThing	regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation	Any process that modulates the rate, frequency, or extent of Wnt signaling through beta-catenin that results in the formation of the neural plate anterior/posterior pattern.	tmpzr1t_l9r_go_relaxed.owl	regulation of canonical Wnt-activated signaling pathway involved in neural plate anterior/posterior pattern formation|regulation of canonical Wnt receptor signalling pathway involved in neural plate anterior/posterior pattern formation|regulation of canonical Wnt receptor signaling pathway involved in neural plate anterior/posterior pattern formation|regulation of Wnt receptor signaling pathway through beta-catenin involved in neural plate anterior/posterior pattern formation							dph	2009-08-11T01:48:52Z					biological_process											owl:Class	
GO:0106335	biolink:NamedThing	tRNA (carboxymethyluridine(34)-5-O)-methyltransferase activity	Catalysis of the reaction: carboxymethyluridine34 in tRNA + S-adenosyl-L-methionine = 5-(2-methoxy-2-oxoethyl)uridine34 in tRNA + S-adenosyl-L-homocysteine.	tmpzr1t_l9r_go_relaxed.owl					EC:2.1.1.229|RHEA:43208			hjd	2020-10-27T21:34:30Z					molecular_function											owl:Class	
GO:0052158	biolink:NamedThing	modulation by symbiont of host resistance gene-dependent defense response	Any process in which a symbiont modulates the frequency, rate or extent of the resistance gene-dependent defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	modulation by organism of pathogen-race/host plant cultivar-specific resistance in symbiont|modulation by organism of resistance gene-dependent defense response of other organism involved in symbiotic interaction|modulation by organism of defense response in host by specific elicitors|modulation by organism of host gene-for-gene resistance											GO:0052297		biological_process											owl:Class	
GO:0090222	biolink:NamedThing	centrosome-templated microtubule nucleation	The 'de novo' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates from the centrosome.	tmpzr1t_l9r_go_relaxed.owl								tb	2010-01-13T10:52:36Z					biological_process											owl:Class	
GO:0051418	biolink:NamedThing	microtubule nucleation by microtubule organizing center	The 'de novo' formation of a microtubule, mediated by the microtubule organizing center.	tmpzr1t_l9r_go_relaxed.owl	MTOC-mediated microtubule nucleation|microtubule nucleation by microtubule organising centre|microtubule organizing center-mediated microtubule nucleation|microtubule nucleation by MTOC													biological_process											owl:Class	
GO:0008703	biolink:NamedThing	5-amino-6-(5-phosphoribosylamino)uracil reductase activity	Catalysis of the reaction: 5-amino-6-(5-phosphoribitylamino)uracil + NADP(+) = 5-amino-6-(5-phosphoribosylamino)uracil + H(+) + NADPH.	tmpzr1t_l9r_go_relaxed.owl	aminodioxyphosphoribosylaminopyrimidine reductase activity|5-amino-6-(5'-phosphoribosylamino)uracil reductase activity|5-amino-6-(5-phosphoribitylamino)uracil:NADP+ 1'-oxidoreductase activity				EC:1.1.1.193|KEGG_REACTION:R03458|RHEA:17845|MetaCyc:RIBOFLAVINSYNREDUC-RXN									molecular_function											owl:Class	
GO:0044742	biolink:NamedThing	envenomation resulting in modulation of sensory perception of pain in other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the modulation of the sensory perception of pain in the bitten organism.	tmpzr1t_l9r_go_relaxed.owl	envenomation resulting in regulation of sensory perception of pain in other organism							jl	2012-11-07T14:26:38Z					biological_process											owl:Class	
GO:0061567	biolink:NamedThing	dCMP phosphorylation	The process of introducing a phosphate group into dCMP, deoxycytidine monophosphate, to produce dCDP. Addition of two phosphate groups produces dCTP.	tmpzr1t_l9r_go_relaxed.owl								dph	2013-08-01T12:54:21Z					biological_process											owl:Class	
GO:0046940	biolink:NamedThing	nucleoside monophosphate phosphorylation	The process of introducing one or more phosphate groups into a nucleoside monophosphate to produce a polyphosphorylated nucleoside.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1901147	biolink:NamedThing	mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis	Any mesenchymal cell apoptotic process that is involved in metanephric nephron morphogenesis.	tmpzr1t_l9r_go_relaxed.owl								pr	2012-07-13T02:41:12Z					biological_process											owl:Class	
GO:0097152	biolink:NamedThing	mesenchymal cell apoptotic process	Any apoptotic process in a mesenchymal cell. A mesenchymal cell is a loosely associated cell that is part of the connective tissue in an organism. Mesenchymal cells give rise to more mature connective tissue cell types.	tmpzr1t_l9r_go_relaxed.owl	mesenchymal cell apoptosis							pr	2011-09-06T02:31:59Z					biological_process											owl:Class	
GO:0060390	biolink:NamedThing	regulation of SMAD protein signal transduction	Any process that modulates the rate, frequency or extent of SMAD protein signal transduction. Pathway-restricted SMAD proteins and common-partner SMAD proteins are involved in the transforming growth factor beta receptor signaling pathways.	tmpzr1t_l9r_go_relaxed.owl	SMAD protein import into nucleus|regulation of SMAD protein nuclear translocation											GO:0007184		biological_process											owl:Class	
GO:0043055	biolink:NamedThing	maintenance of dauer	Maintenance of a nematode during the facultative diapause of the dauer (enduring) larval stage of nematode development.	tmpzr1t_l9r_go_relaxed.owl	maintenance of dormancy in the nematode													biological_process											owl:Class	
GO:1904027	biolink:NamedThing	negative regulation of collagen fibril organization	Any process that stops, prevents or reduces the frequency, rate or extent of collagen fibril organization.	tmpzr1t_l9r_go_relaxed.owl	down regulation of collagen fibril organization|negative regulation of collagen fibril organisation|down-regulation of collagen fibril organization|downregulation of collagen fibril organisation|down-regulation of fibrillar collagen organization|inhibition of collagen fibril organization|down regulation of fibrillar collagen organization|inhibition of collagen fibril organisation|down-regulation of collagen fibril organisation|down regulation of collagen fibril organisation|downregulation of collagen fibril organization|negative regulation of fibrillar collagen organization|downregulation of fibrillar collagen organization|inhibition of fibrillar collagen organization							ae	2015-03-12T12:36:59Z					biological_process											owl:Class	
GO:1903054	biolink:NamedThing	negative regulation of extracellular matrix organization	Any process that stops, prevents or reduces the frequency, rate or extent of extracellular matrix organization.	tmpzr1t_l9r_go_relaxed.owl	downregulation of extracellular matrix organisation|down regulation of extracellular matrix organization and biogenesis|down-regulation of extracellular matrix organisation|inhibition of extracellular matrix organisation|negative regulation of extracellular matrix organization and biogenesis|downregulation of extracellular matrix organization and biogenesis|inhibition of extracellular matrix organization|inhibition of extracellular matrix organization and biogenesis|downregulation of extracellular matrix organization|negative regulation of extracellular matrix organisation|down regulation of extracellular matrix organization|down-regulation of extracellular matrix organization and biogenesis|down regulation of extracellular matrix organisation|down-regulation of extracellular matrix organization							rl	2014-05-23T17:15:47Z					biological_process											owl:Class	
GO:0002717	biolink:NamedThing	positive regulation of natural killer cell mediated immunity	Any process that activates or increases the frequency, rate, or extent of natural killer cell mediated immunity.	tmpzr1t_l9r_go_relaxed.owl	up regulation of natural killer cell mediated immunity|stimulation of natural killer cell mediated immunity|positive regulation of natural killer cell activity|positive regulation of NK cell mediated immunity|positive regulation of NK cell activity|upregulation of natural killer cell mediated immunity|activation of natural killer cell mediated immunity|up-regulation of natural killer cell mediated immunity											GO:0045846		biological_process											owl:Class	
GO:0047802	biolink:NamedThing	cysteine-conjugate transaminase activity	Catalysis of the reaction: 2-oxoglutarate + S-(4-bromophenyl)-L-cysteine = (4-bromophenylsulfanyl)pyruvate + L-glutamate.	tmpzr1t_l9r_go_relaxed.owl	cysteine-conjugate alpha-ketoglutarate transaminase (CAT-1)|cysteine conjugate aminotransferase activity|S-(4-bromophenyl)-L-cysteine:2-oxoglutarate aminotransferase activity				KEGG_REACTION:R04338|RHEA:13485|MetaCyc:CYSTEINE-CONJUGATE-TRANSAMINASE-RXN|EC:2.6.1.75									molecular_function											owl:Class	
GO:0042371	biolink:NamedThing	vitamin K biosynthetic process	The chemical reactions and pathways resulting in the formation of any of the forms of vitamin K, quinone-derived vitamins which are involved in the synthesis of blood-clotting factors in mammals.	tmpzr1t_l9r_go_relaxed.owl	naphthoquinone metabolic process|vitamin K synthesis|vitamin K formation|vitamin K anabolism|vitamin K biosynthesis|naphthoquinone metabolism													biological_process											owl:Class	
GO:0004914	biolink:NamedThing	interleukin-5 receptor activity	Combining with interleukin-5 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	IL-5R|IL-5 receptor activity													molecular_function											owl:Class	
GO:0016049	biolink:NamedThing	cell growth	The process in which a cell irreversibly increases in size over time by accretion and biosynthetic production of matter similar to that already present.	tmpzr1t_l9r_go_relaxed.owl	non-developmental growth of a unicellular organism|metabolism resulting in cell growth|growth of cell|cell expansion|metabolic process resulting in cell growth|cellular growth|non-developmental cell growth											GO:0048591		biological_process											owl:Class	
GO:1990949	biolink:NamedThing	metaphase/anaphase transition of meiosis I	The cell cycle process in which a cell progresses from metaphase to anaphase as part of meiosis I.	tmpzr1t_l9r_go_relaxed.owl	meiosis I metaphase/anaphase transition|first meiotic metaphase/anaphase transition							mah	2016-04-25T15:27:32Z					biological_process											owl:Class	
GO:0061982	biolink:NamedThing	meiosis I cell cycle process	A process that contributes to the first meiotic division. The first meiotic division is the reductive division resulting in the separation of homologous chromosome pairs.	tmpzr1t_l9r_go_relaxed.owl	first meiotic cell division							dph	2018-02-14T22:27:20Z					biological_process											owl:Class	
GO:2000885	biolink:NamedThing	galactoglucomannan catabolic process	The chemical reactions and pathways resulting in the breakdown of a galactoglucomannan.	tmpzr1t_l9r_go_relaxed.owl	galactoglucomannan catabolism							jl	2011-07-28T09:24:11Z					biological_process											owl:Class	
GO:0010392	biolink:NamedThing	galactoglucomannan metabolic process	The chemical reactions and pathways involving galactoglucomannan, a polysaccharide composed of D-glucose, D-galactose and D-mannose. The mannose units form the backbone structure (a linear main chain) decorated with a mixture of D-glucose and D-galactose side-units.	tmpzr1t_l9r_go_relaxed.owl	galactoglucomannan metabolism													biological_process											owl:Class	
GO:0047878	biolink:NamedThing	erythritol kinase activity	Catalysis of the reaction: ATP + erythritol = D-erythritol 4-phosphate + ADP + 2 H(+).	tmpzr1t_l9r_go_relaxed.owl	ATP:erythritol 4-phosphotransferase activity|erythritol kinase (phosphorylating)				KEGG_REACTION:R02430|RHEA:20708|EC:2.7.1.27|MetaCyc:ERYTHRITOL-KINASE-RXN									molecular_function											owl:Class	
GO:0043413	biolink:NamedThing	macromolecule glycosylation	The covalent attachment of a glycosyl residue to one or more monomeric units in a polypeptide, polynucleotide, polysaccharide, or other biological macromolecule.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0098549	biolink:NamedThing	somatic ring canal	A stable intercellular bridge between somatic cells.  Examples include the intercellular bridges between ovarian follicle cells in insects and between imaginal disc cells in insects.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0045171	biolink:NamedThing	intercellular bridge	A direct connection between the cytoplasm of two cells that is formed following the completion of cleavage furrow ingression during cell division. They are usually present only briefly prior to completion of cytokinesis. However, in some cases, such as the bridges between germ cells during their development, they become stabilised.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:1903895	biolink:NamedThing	negative regulation of IRE1-mediated unfolded protein response	Any process that stops, prevents or reduces the frequency, rate or extent of the IRE1-mediated unfolded protein response.	tmpzr1t_l9r_go_relaxed.owl	down regulation of IRE1 signaling in response to endoplasmic reticulum stress|inhibition of IRE1 branch of UPR|negative regulation of ERN1-mediated unfolded protein response|down-regulation of IRE1 signaling in response to endoplasmic reticulum stress|down-regulation of inositol-requiring transmembrane kinase/endonuclease signal transduction|down regulation of UPR signaling by IRE1 stress sensor|down regulation of IRE1p unfolded protein response|downregulation of IRE1 signaling in response to endoplasmic reticulum stress|downregulation of IRE1p unfolded protein response|down regulation of IRE1 branch of UPR|inhibition of IRE1alpha unfolded protein response|inhibition of IRE1p unfolded protein response|down regulation of IRE1alpha unfolded protein response|downregulation of endoplasmic reticulum unfolded protein response; IRE1 signaling|negative regulation of IRE1alpha unfolded protein response|negative regulation of IRE1p unfolded protein response|negative regulation of IRE1 signaling in response to endoplasmic reticulum stress|inhibition of IRE1 signaling in response to endoplasmic reticulum stress|downregulation of inositol-requiring transmembrane kinase/endonuclease signal transduction|negative regulation of UPR signaling by IRE1 stress sensor|down regulation of IRE1-mediated unfolded protein response|down-regulation of UPR signaling by IRE1 stress sensor|downregulation of IRE1alpha unfolded protein response|negative regulation of IRE1 branch of UPR|negative regulation of endoplasmic reticulum unfolded protein response; IRE1 signaling|down-regulation of IRE1p unfolded protein response|negative regulation of inositol-requiring transmembrane kinase/endonuclease signal transduction|down-regulation of IRE1alpha unfolded protein response|inhibition of endoplasmic reticulum unfolded protein response; IRE1 signaling|downregulation of IRE1 branch of UPR|downregulation of IRE1-mediated unfolded protein response|down regulation of endoplasmic reticulum unfolded protein response; IRE1 signaling|down-regulation of endoplasmic reticulum unfolded protein response; IRE1 signaling|inhibition of IRE1-mediated unfolded protein response|inhibition of inositol-requiring transmembrane kinase/endonuclease signal transduction|down-regulation of IRE1 branch of UPR|down-regulation of IRE1-mediated unfolded protein response|down regulation of inositol-requiring transmembrane kinase/endonuclease signal transduction|inhibition of UPR signaling by IRE1 stress sensor|downregulation of UPR signaling by IRE1 stress sensor							bf	2015-02-09T10:17:55Z					biological_process											owl:Class	
GO:0062241	biolink:NamedThing	double strand break-nuclear membrane anchor activity	Binding to DNA double strand breaks and the nuclear inner membrane, in order to facilitate DNA repair.	tmpzr1t_l9r_go_relaxed.owl	DNA repair factory							dph	2020-04-20T18:23:59Z					molecular_function											owl:Class	
GO:0002804	biolink:NamedThing	positive regulation of antifungal peptide production	Any process that activates or increases the frequency, rate, or extent of antifungal peptide production.	tmpzr1t_l9r_go_relaxed.owl	upregulation of antifungal peptide production|up-regulation of antifungal peptide production|activation of antifungal peptide production|up regulation of antifungal peptide production|stimulation of antifungal peptide production													biological_process											owl:Class	
GO:0002225	biolink:NamedThing	positive regulation of antimicrobial peptide production	Any process that activates or increases the frequency, rate, or extent of antimicrobial peptide production.	tmpzr1t_l9r_go_relaxed.owl	stimulation of antimicrobial peptide production|up-regulation of antimicrobial peptide production|antimicrobial peptide induction|upregulation of antimicrobial peptide production|activation of antimicrobial peptide production|up regulation of antimicrobial peptide production													biological_process											owl:Class	
GO:0009761	biolink:NamedThing	CAM photosynthesis	The combination of atmospheric CO2 with a 3-carbon molecule phosphoenol pyruvate (PEP) to make malic acid. The malic acid is then passed into the vacuole where it is stored until daylight, when it is shuttled back out to be used as a substrate in the light reaction of photosynthesis.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Crassulacean_acid_metabolism									biological_process											owl:Class	
GO:0042753	biolink:NamedThing	positive regulation of circadian rhythm	Any process that activates or increases the frequency, rate or extent of a circadian rhythm behavior.	tmpzr1t_l9r_go_relaxed.owl	upregulation of circadian rhythm|up regulation of circadian rhythm|activation of circadian rhythm|up-regulation of circadian rhythm|stimulation of circadian rhythm													biological_process											owl:Class	
GO:0102285	biolink:NamedThing	1-deoxy-11-oxopentalenate oxygenase activity	Catalysis of the reaction: 1-deoxy-11-oxopentalenate + O2 + NADPH + H+ = pentalenolactone D + H2O + NADP.	tmpzr1t_l9r_go_relaxed.owl					EC:1.14.13.170|RHEA:34635|MetaCyc:RXN-12654									molecular_function											owl:Class	
GO:0046794	biolink:NamedThing	transport of virus	The directed movement of a virus, or part of a virus, into, out of, or within a host cell.	tmpzr1t_l9r_go_relaxed.owl	viral transport|virion transport													biological_process											owl:Class	
GO:0047976	biolink:NamedThing	hamamelose kinase activity	Catalysis of the reaction: D-hamamelose + ATP = D-hamamelose 2'-phosphate + ADP + 2 H(+).	tmpzr1t_l9r_go_relaxed.owl	hamamelose kinase (phosphorylating)|ATP:D-hamamelose 2'-phosphotransferase activity|hamamelosekinase (ATP: hamamelose 2'-phosphotransferase)|ATP/hamamelose 2'-phosphotransferase activity				RHEA:22796|MetaCyc:HAMAMELOSE-KINASE-RXN|EC:2.7.1.102|KEGG_REACTION:R03766									molecular_function											owl:Class	
GO:0007306	biolink:NamedThing	eggshell chorion assembly	Construction of the chorion portion of the eggshell, which comprises the channels for gas exchange in an insect eggshell.	tmpzr1t_l9r_go_relaxed.owl	insect chorion formation|eggshell chorion formation													biological_process											owl:Class	
GO:0061845	biolink:NamedThing	neuron projection branch point	The location where a secondary projection arises from a neuron projection.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0071798	biolink:NamedThing	response to prostaglandin D	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin D stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to prostaglandin D stimulus							mah	2010-09-03T10:48:03Z					biological_process											owl:Class	
GO:0047112	biolink:NamedThing	pyruvate oxidase activity	Catalysis of the reaction: H(+) + O(2) + phosphate + pyruvate = acetyl phosphate + CO(2) + H(2)O(2).	tmpzr1t_l9r_go_relaxed.owl	phosphate-dependent pyruvate oxidase activity|pyruvic oxidase activity|pyruvate:oxygen 2-oxidoreductase (phosphorylating)				MetaCyc:1.2.3.3-RXN|EC:1.2.3.3|KEGG_REACTION:R00207|RHEA:20848									molecular_function											owl:Class	
GO:0030273	biolink:NamedThing	melanin-concentrating hormone receptor activity	Combining with the cyclic peptide hormone melanin-concentrating hormone to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	MCH receptor													molecular_function											owl:Class	
GO:0016500	biolink:NamedThing	protein-hormone receptor activity	Combining with a protein hormone to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0001796	biolink:NamedThing	regulation of type IIa hypersensitivity	Any process that modulates the frequency, rate, or extent of type IIa hypersensitivity, a type of inflammatory response.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1902348	biolink:NamedThing	cellular response to strigolactone	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a strigolactone stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to strigolactone analog GR24							dhl	2013-08-08T18:45:05Z					biological_process											owl:Class	
GO:1902347	biolink:NamedThing	response to strigolactone	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a strigolactone stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to strigolactone analog GR24							dhl	2013-08-08T18:44:57Z					biological_process											owl:Class	
GO:0010991	biolink:NamedThing	negative regulation of SMAD protein complex assembly	Any process that decreases the rate, frequency, or extent of SMAD protein complex assembly. SMAD protein complex assembly is the aggregation, arrangement and bonding together of a set of components to form a protein complex that contains SMAD proteins.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-06-03T11:30:44Z					biological_process											owl:Class	
GO:0052597	biolink:NamedThing	diamine oxidase activity	Catalysis of the reaction: a diamine + H2O + O2 = a monoamine + NH3 + hydrogen peroxide.	tmpzr1t_l9r_go_relaxed.owl	diamine:oxygen oxidoreductase (deaminating) activity				MetaCyc:RXN-9599|EC:1.4.3.22									molecular_function											owl:Class	
GO:0010779	biolink:NamedThing	meiotic DNA repair synthesis involved in meiotic gene conversion	The synthesis of DNA proceeding from the broken 3' single-strand DNA end that uses the homologous intact duplex as the template resulting in meiotic gene conversion. Meiotic gene conversion is the cell cycle process in which genetic information is transferred from one helix to another.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0000711	biolink:NamedThing	meiotic DNA repair synthesis	During meiosis, the synthesis of DNA proceeding from the broken 3' single-strand DNA end that uses the homologous intact duplex as the template.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0140329	biolink:NamedThing	lysophospholipid translocation	The movement of a lysophospholipid molecule from one leaflet of a membrane bilayer to the opposite leaflet.	tmpzr1t_l9r_go_relaxed.owl								pg	2019-05-03T07:26:52Z					biological_process											owl:Class	
GO:0051977	biolink:NamedThing	lysophospholipid transport	The directed movement of phospholipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A lysophospholipid is a phospholipid that lacks one of its fatty acyl chains; it is an intermediate formed during digestion of dietary and biliary phospholipids.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0015277	biolink:NamedThing	kainate selective glutamate receptor activity	An ionotropic glutamate receptor activity that exhibits fast gating by glutamate, acts by opening a cation channel permeable to sodium and potassium, and for which kainate is an agonist.	tmpzr1t_l9r_go_relaxed.owl						Note that this term represents an activity and not a gene product. Consider also annotating to the molecular function terms 'ionotropic glutamate receptor activity ; GO:0004970' and 'cation channel activity ; GO:0005261'.								molecular_function											owl:Class	
GO:0004970	biolink:NamedThing	ionotropic glutamate receptor activity	Catalysis of the transmembrane transfer of an ion by a channel that opens when glutamate has been bound by the channel complex or one of its constituent parts.	tmpzr1t_l9r_go_relaxed.owl						Note that this term represents an activity and not a gene product. Consider also annotating to the molecular function terms 'glutamate-gated ion channel activity ; GO:0005234' and 'cation channel activity ; GO:0005261'.								molecular_function											owl:Class	
GO:1901278	biolink:NamedThing	D-ribose 5-phosphate metabolic process	The chemical reactions and pathways involving D-ribose 5-phosphate.	tmpzr1t_l9r_go_relaxed.owl	D-ribose 5-phosphate metabolism							yaf	2012-08-17T14:59:58Z					biological_process											owl:Class	
GO:0019693	biolink:NamedThing	ribose phosphate metabolic process	The chemical reactions and pathways involving ribose phosphate, any phosphorylated ribose sugar.	tmpzr1t_l9r_go_relaxed.owl	ribose phosphate metabolism													biological_process											owl:Class	
GO:0043376	biolink:NamedThing	regulation of CD8-positive, alpha-beta T cell differentiation	Any process that modulates the frequency, rate, or extent of CD8-positive, alpha-beta T cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	regulation of CD8-positive T-cell differentiation|regulation of CD8-positive T lymphocyte differentiation|regulation of CD8-positive, alpha-beta T cell development|regulation of CD8-positive, alpha beta T-cell differentiation|regulation of CD8-positive T-lymphocyte differentiation|regulation of CD8-positive, alpha beta T-lymphocyte differentiation|regulation of CD8-positive, alpha beta T lymphocyte differentiation					Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.								biological_process											owl:Class	
GO:0046637	biolink:NamedThing	regulation of alpha-beta T cell differentiation	Any process that modulates the frequency, rate or extent of alpha-beta T cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	regulation of alpha-beta T cell development|regulation of alpha-beta T-lymphocyte differentiation|regulation of alpha-beta T lymphocyte differentiation|regulation of alpha-beta T-cell differentiation					Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.								biological_process											owl:Class	
GO:0062134	biolink:NamedThing	positive regulation of L-glutamine biosynthetic process	Any process that starts, increases the frequency, rate or extent of L-glutamine biosynthesis.	tmpzr1t_l9r_go_relaxed.owl								dph	2019-06-27T13:49:29Z					biological_process											owl:Class	
GO:0002909	biolink:NamedThing	negative regulation of peripheral B cell deletion	Any process that stops, prevents, or reduces the frequency, rate, or extent of peripheral B cell deletion.	tmpzr1t_l9r_go_relaxed.owl	inhibition of peripheral B cell deletion|down-regulation of peripheral B cell deletion|downregulation of peripheral B cell deletion|down regulation of peripheral B cell deletion													biological_process											owl:Class	
GO:1905781	biolink:NamedThing	negative regulation of phosphatidylserine exposure on apoptotic cell surface	Any process that stops, prevents or reduces the frequency, rate or extent of phosphatidylserine exposure on apoptotic cell surface.	tmpzr1t_l9r_go_relaxed.owl	down regulation of externalization of phosphatidylserine|downregulation of phosphatidylserine exposure on apoptotic cell surface|inhibition of externalization of phosphatidylserine|down-regulation of phosphatidylserine exposure on apoptotic cell surface|down-regulation of externalization of phosphatidylserine|down regulation of phosphatidylserine exposure on apoptotic cell surface|inhibition of phosphatidylserine exposure on apoptotic cell surface|negative regulation of externalization of phosphatidylserine|downregulation of externalization of phosphatidylserine							kmv	2017-01-04T15:19:14Z					biological_process											owl:Class	
GO:1905780	biolink:NamedThing	regulation of phosphatidylserine exposure on apoptotic cell surface	Any process that modulates the frequency, rate or extent of phosphatidylserine exposure on apoptotic cell surface.	tmpzr1t_l9r_go_relaxed.owl	regulation of externalization of phosphatidylserine							kmv	2017-01-04T15:18:52Z					biological_process											owl:Class	
GO:0010819	biolink:NamedThing	regulation of T cell chemotaxis	Any process that modulates the rate, frequency or extent of T cell chemotaxis. T cell chemotaxis is the directed movement of a T cell in response to an external stimulus.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0102838	biolink:NamedThing	1-18:1-2-16:2-monogalactosyldiacylglycerol desaturase activity	Catalysis of the reaction: 1-18:1-2-16:2-monogalactosyldiacylglycerol + O2 + a reduced electron acceptor <=> 1-18:2-2-16:2-monogalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor.	tmpzr1t_l9r_go_relaxed.owl					EC:1.14.19.23|MetaCyc:RXN-8298									molecular_function											owl:Class	
GO:2000726	biolink:NamedThing	negative regulation of cardiac muscle cell differentiation	Any process that stops, prevents or reduces the frequency, rate or extent of cardiac muscle cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of cardiomyocyte differentiation|negative regulation of heart muscle cell differentiation							vk	2011-06-08T10:51:11Z					biological_process											owl:Class	
GO:2000725	biolink:NamedThing	regulation of cardiac muscle cell differentiation	Any process that modulates the frequency, rate or extent of cardiac muscle cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	regulation of heart muscle cell differentiation|regulation of cardiomyocyte differentiation							vk	2011-06-08T10:51:06Z					biological_process											owl:Class	
GO:1900695	biolink:NamedThing	regulation of N',N'',N'''-triacetylfusarinine C biosynthetic process	Any process that modulates the frequency, rate or extent of N',N'',N'''-triacetylfusarinine C biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of N',N'',N'''-triacetylfusarinine C formation|regulation of N',N'',N'''-triacetylfusarinine C synthesis|regulation of N',N'',N'''-triacetylfusarinine C biosynthesis|regulation of N',N'',N'''-triacetylfusarinine C anabolism							di	2012-05-22T04:54:24Z					biological_process											owl:Class	
GO:0006740	biolink:NamedThing	NADPH regeneration	A metabolic process that generates a pool of NADPH by the reduction of NADP+.	tmpzr1t_l9r_go_relaxed.owl	NADP (reduced) regeneration|reduced NADP regeneration|reduced nicotinamide adenine dinucleotide phosphate regeneration													biological_process											owl:Class	
GO:0075308	biolink:NamedThing	negative regulation of conidium formation	Any process that stops, prevents, or reduces the frequency, rate or extent of conidium formation, a process of producing non-motile spores, called conidia, via mitotic asexual reproduction in higher fungi. Conidia are haploid cells genetically identical to their haploid parent. They are produced by conversion of hyphal elements, or are borne on sporogenous cells on or within specialized structures termed conidiophores, and participate in dispersal of the fungus.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0044790	biolink:NamedThing	suppression of viral release by host	A process in which a host organism stops, prevents or reduces the frequency, rate or extent of the release of a virus with which it is infected, from its cells.	tmpzr1t_l9r_go_relaxed.owl	inhibition of viral release from host cell|negative regulation by host of viral release from host cell|downregulation of release of virus from host|negative regulation of viral shedding|down regulation of release of virus from host|down-regulation of viral release|down-regulation of viral release from host cell|downregulation of viral release from host cell|inhibition of release of virus from host|down-regulation of viral shedding|down regulation of viral shedding|downregulation of viral release|negative regulation of viral release from host cell|negative regulation of viral release|negative regulation of viral exit|downregulation of viral shedding|negative regulation of release of virus from host|inhibition of viral release|down-regulation of release of virus from host|downregulation of viral exit|down regulation of viral release from host cell|down regulation of viral exit|down-regulation of viral exit|inhibition of viral shedding|down regulation of viral release|inhibition of viral exit	https://github.com/geneontology/go-ontology/issues/22166						jl	2013-06-06T10:51:27Z			GO:1902187		biological_process											owl:Class	
GO:0042073	biolink:NamedThing	intraciliary transport	The bidirectional movement of large protein complexes along microtubules within a cilium, mediated by motor proteins.	tmpzr1t_l9r_go_relaxed.owl	intraflagellar transport involved in microtubule-based flagellum organisation|intraflagellar transport involved in cilium organization|intraflagellar transport|IFT				Wikipedia:Intraflagellar_transport	Note that we deem cilium and microtubule-based flagellum to be equivalent.						GO:0035734		biological_process											owl:Class	
GO:0010970	biolink:NamedThing	transport along microtubule	The movement of organelles or other particles from one location in the cell to another along microtubules, driven by motor activity.	tmpzr1t_l9r_go_relaxed.owl	movement along microtubule|microtubule-based transport|establishment of localization by movement along microtubule							tb	2009-05-27T10:56:08Z					biological_process											owl:Class	
GO:0102622	biolink:NamedThing	linuron hydrolase activity	Catalysis of the reaction: linuron + H2O <=> N,O-dimethylhydroxylamine + carbon dioxide + 3,4-dichloroaniline.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-15526									molecular_function											owl:Class	
GO:1901896	biolink:NamedThing	positive regulation of ATPase-coupled calcium transmembrane transporter activity	Any process that activates or increases the frequency, rate or extent of an ATPase-coupled calcium transmembrane transporter activity.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of Ca2+-pumping ATPase activity|up-regulation of Ca2+-pumping ATPase activity|upregulation of ATP phosphohydrolase (Ca2+-transporting)|activation of sarco(endo)plasmic reticulum Ca2+-ATPase|up-regulation of calcium-transporting ATPase activity|up regulation of calcium ABC transporter|positive regulation of sarco(endo)plasmic reticulum Ca2+-ATPase|activation of calcium ABC transporter|activation of plasma membrane Ca-ATPase|up regulation of sarco(endo)plasmic reticulum Ca2+-ATPase|upregulation of Ca2+-transporting ATPase activity|positive regulation of plasma membrane Ca-ATPase|activation of sarcoplasmic reticulum ATPase|up-regulation of calcium ABC transporter|activation of Ca2+-pumping ATPase activity|up-regulation of calcium transporting ATPase activity|activation of ATP phosphohydrolase (Ca2+-transporting)|up regulation of Ca2+-pumping ATPase activity|up regulation of calcium pump|positive regulation of calcium-translocating P-type ATPase activity|up regulation of Ca(2+)-transporting ATPase activity|up-regulation of Ca2+-transporting ATPase activity|positive regulation of Ca(2+)-transporting ATPase activity|upregulation of Ca(2+)-transporting ATPase activity|up regulation of calcium transporting ATPase activity|upregulation of calcium-translocating P-type ATPase activity|up regulation of calcium efflux ATPase|up-regulation of plasma membrane Ca-ATPase|activation of calcium-translocating P-type ATPase activity|up regulation of sarcoplasmic reticulum ATPase|positive regulation of calcium ABC transporter|activation of Ca(2+)-transporting ATPase activity|up-regulation of sarco(endo)plasmic reticulum Ca2+-ATPase|up regulation of plasma membrane Ca-ATPase|upregulation of Ca2+-pumping ATPase activity|up regulation of calcium-translocating P-type ATPase activity|activation of calcium-transporting ATPase activity|upregulation of sarcoplasmic reticulum ATPase|activation of calcium pump|up-regulation of ATP phosphohydrolase (Ca2+-transporting)|positive regulation of calcium transporting ATPase activity|upregulation of calcium ABC transporter|positive regulation of calcium pump|activation of calcium transporting ATPase activity|positive regulation of calcium efflux ATPase|positive regulation of ATP phosphohydrolase (Ca2+-transporting)|positive regulation of sarcoplasmic reticulum ATPase|positive regulation of calcium-transporting ATPase activity|upregulation of calcium efflux ATPase|activation of calcium efflux ATPase|up-regulation of calcium pump|upregulation of calcium-transporting ATPase activity|up-regulation of calcium efflux ATPase|up-regulation of Ca(2+)-transporting ATPase activity|upregulation of calcium transporting ATPase activity|up regulation of calcium-transporting ATPase activity|up regulation of Ca2+-transporting ATPase activity|upregulation of calcium pump|upregulation of plasma membrane Ca-ATPase|up-regulation of calcium-translocating P-type ATPase activity|up regulation of ATP phosphohydrolase (Ca2+-transporting)|activation of Ca2+-transporting ATPase activity|positive regulation of Ca2+-transporting ATPase activity|upregulation of sarco(endo)plasmic reticulum Ca2+-ATPase|up-regulation of sarcoplasmic reticulum ATPase							rl	2013-02-06T21:18:29Z					biological_process											owl:Class	
GO:1901021	biolink:NamedThing	positive regulation of calcium ion transmembrane transporter activity	Any process that activates or increases the frequency, rate or extent of calcium ion transmembrane transporter activity.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of calcium ion transmembrane transporter activity|upregulation of calcium ion transmembrane transporter activity|up regulation of calcium ion transmembrane transporter activity|activation of calcium ion transmembrane transporter activity							rl	2012-06-15T07:54:40Z					biological_process											owl:Class	
GO:0015240	biolink:NamedThing	amiloride transmembrane transporter activity	Enables the transfer of amiloride from one side of a membrane to the other. Amiloride is a potent and specific inhibitor of sodium ion entry into cells. It is used as a potassium-sparing diuretic.	tmpzr1t_l9r_go_relaxed.owl	amiloride transporter activity													molecular_function											owl:Class	
GO:0043157	biolink:NamedThing	response to cation stress	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of cation stress, an increase or decrease in the concentration of positively charged ions in the environment.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0001542	biolink:NamedThing	ovulation from ovarian follicle	The process leading to the rupture of the follicle, releasing the centrally located oocyte into the oviduct. An example of this is found in Mus musculus.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0030728	biolink:NamedThing	ovulation	The release of a mature ovum/oocyte from an ovary.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Ovulation									biological_process											owl:Class	
GO:1902371	biolink:NamedThing	negative regulation of tRNA catabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of tRNA catabolic process.	tmpzr1t_l9r_go_relaxed.owl	inhibition of tRNA breakdown|down-regulation of tRNA breakdown|downregulation of tRNA catabolic process|down regulation of tRNA breakdown|negative regulation of tRNA breakdown|down regulation of tRNA catabolic process|down-regulation of tRNA degradation|downregulation of tRNA breakdown|downregulation of tRNA catabolism|down-regulation of tRNA catabolic process|down regulation of tRNA catabolism|negative regulation of tRNA degradation|down regulation of tRNA degradation|inhibition of tRNA catabolic process|down-regulation of tRNA catabolism|negative regulation of tRNA catabolism|inhibition of tRNA degradation|inhibition of tRNA catabolism|downregulation of tRNA degradation							bf	2013-08-22T15:08:20Z					biological_process											owl:Class	
GO:1902369	biolink:NamedThing	negative regulation of RNA catabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of RNA catabolic process.	tmpzr1t_l9r_go_relaxed.owl	downregulation of RNA catabolic process|down regulation of RNA breakdown|down regulation of RNA catabolic process|inhibition of RNA catabolism|negative regulation of RNA degradation|negative regulation of RNA catabolism|down regulation of RNA catabolism|downregulation of RNA breakdown|down regulation of RNA degradation|down-regulation of RNA degradation|downregulation of RNA catabolism|down-regulation of RNA catabolism|inhibition of RNA degradation|inhibition of RNA breakdown|down-regulation of RNA breakdown|inhibition of RNA catabolic process|down-regulation of RNA catabolic process|downregulation of RNA degradation|negative regulation of RNA breakdown							bf	2013-08-22T14:59:39Z					biological_process											owl:Class	
GO:0030139	biolink:NamedThing	endocytic vesicle	A membrane-bounded intracellular vesicle formed by invagination of the plasma membrane around an extracellular substance. Endocytic vesicles fuse with early endosomes to deliver the cargo for further sorting.	tmpzr1t_l9r_go_relaxed.owl	endocytotic vesicle|endocytotic transport vesicle				NIF_Subcellular:sao1362520468									cellular_component											owl:Class	
GO:0046678	biolink:NamedThing	response to bacteriocin	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bacteriocin stimulus. A bacteriocin is a protein substance released by certain bacteria that kills but does not lyse closely related strains of bacteria. Specific bacteriocins attach to specific receptors on cell walls and induce specific metabolic block, e.g. cessation of nucleic acid or protein synthesis of oxidative phosphorylation.	tmpzr1t_l9r_go_relaxed.owl	bacteriocin susceptibility/resistance													biological_process											owl:Class	
GO:0010930	biolink:NamedThing	negative regulation of auxin mediated signaling pathway	Any process that decreases the rate, frequency or extent of auxin mediated signaling pathway. Auxin mediated signaling pathway is the series of molecular signals generated in response to detection of auxin.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of auxin mediated signalling pathway													biological_process											owl:Class	
GO:0044564	biolink:NamedThing	envenomation resulting in occlusion of the pore of voltage-gated potassium channel in other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with a resultant blocking of a voltage-gated potassium channel, inhibiting the pore's activity, in the bitten/stung organism.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-04-05T04:14:24Z					biological_process											owl:Class	
GO:0044562	biolink:NamedThing	envenomation resulting in negative regulation of voltage-gated potassium channel activity in other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with a resultant negative regulation of the activity of a voltage-gated potassium channel in the bitten/stung organism.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-04-05T04:01:49Z					biological_process											owl:Class	
GO:1904715	biolink:NamedThing	negative regulation of chaperone-mediated autophagy	Any process that stops, prevents or reduces the frequency, rate or extent of chaperone-mediated autophagy.	tmpzr1t_l9r_go_relaxed.owl	inhibition of CMA|negative regulation of CMA|down-regulation of CMA|down regulation of CMA|down regulation of chaperone-mediated autophagy|inhibition of chaperone-mediated autophagy|down-regulation of chaperone-mediated autophagy|downregulation of CMA|downregulation of chaperone-mediated autophagy							pad	2015-10-06T08:49:09Z					biological_process											owl:Class	
GO:0010507	biolink:NamedThing	negative regulation of autophagy	Any process that stops, prevents, or reduces the frequency, rate or extent of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0008333	biolink:NamedThing	endosome to lysosome transport	The directed movement of substances from endosomes to lysosomes.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0035920	biolink:NamedThing	negative regulation of high voltage-gated calcium channel activity in other organism	Any process in which an organism stops, prevents or reduces the frequency, rate or extent of the activity of a high voltage-gated calcium channel in another organism. A high voltage-gated channel is a channel whose open state is dependent on high voltage across the membrane in which it is embedded.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of high voltage gated calcium channel activity in other organism|negative regulation of high voltage-dependent calcium channel activity in other organism|down-regulation of high voltage-gated calcium channel activity in other organism|inhibition of high voltage-gated calcium channel activity in other organism|downregulation of high voltage-gated calcium channel activity in other organism							bf	2011-07-01T12:00:23Z					biological_process											owl:Class	
GO:0060041	biolink:NamedThing	retina development in camera-type eye	The process whose specific outcome is the progression of the retina over time, from its formation to the mature structure. The retina is the innermost layer or coating at the back of the eyeball, which is sensitive to light and in which the optic nerve terminates.	tmpzr1t_l9r_go_relaxed.owl	retina development in camera-style eye|retinal development											GO:0002073		biological_process											owl:Class	
GO:1905416	biolink:NamedThing	regulation of amoeboid sperm motility	Any process that modulates the frequency, rate or extent of amoeboid sperm motility.	tmpzr1t_l9r_go_relaxed.owl	regulation of ameboid sperm motility|regulation of ameboid sperm movement|regulation of amoeboid sperm movement							pr	2016-09-01T11:28:48Z					biological_process											owl:Class	
GO:0098813	biolink:NamedThing	nuclear chromosome segregation	The process in which genetic material, in the form of nuclear chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets. Nuclear chromosome segregation begins with the condensation of chromosomes, includes chromosome separation, and ends when chromosomes have completed movement to the spindle poles.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0007059	biolink:NamedThing	chromosome segregation	The process in which genetic material, in the form of chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets. In eukaryotes, chromosome segregation begins with the condensation of chromosomes, includes chromosome separation, and ends when chromosomes have completed movement to the spindle poles.	tmpzr1t_l9r_go_relaxed.owl	chromosome transmission|chromosome division				Wikipedia:Chromosome_segregation									biological_process											owl:Class	
GO:0061703	biolink:NamedThing	pyroptosome complex	A protein complex that consists of an assemble of ASC dimers that is capable of inducing pyroptosis.	tmpzr1t_l9r_go_relaxed.owl	ASC pyroptosome							dph	2015-05-08T14:43:37Z					cellular_component											owl:Class	
GO:0008499	biolink:NamedThing	UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity	Catalysis of the reaction: UDP-galactose + N-acetylglucosamine = galactose-beta-1,3-N-acetylglucosamine + UDP.	tmpzr1t_l9r_go_relaxed.owl	UDP-galactose beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity|beta3Gal-Ts activity|UDP-Gal:beta-GlcNAc beta-1,3-galactosyltransferase activity|beta-1,3-GalTase activity				Reactome:R-HSA-914010|Reactome:R-HSA-9603989									molecular_function											owl:Class	
GO:1902554	biolink:NamedThing	serine/threonine protein kinase complex	A protein complex which is capable of protein serine/threonine kinase activity.	tmpzr1t_l9r_go_relaxed.owl	PDR16 complex dimer|PDR16 complex homodimer					An example is IRE1 in S. cerevisiae (UniProt ID P32361) in PMID:18191223 (inferred from direct assay).		bhm	2013-12-06T16:06:12Z					cellular_component											owl:Class	
GO:0006039	biolink:NamedThing	cell wall chitin catabolic process	The chemical reactions and pathways resulting in the breakdown of cell wall chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues, found in the walls of cells.	tmpzr1t_l9r_go_relaxed.owl	cell wall chitin breakdown|cell wall chitin catabolism|cell wall chitin degradation													biological_process											owl:Class	
GO:0006037	biolink:NamedThing	cell wall chitin metabolic process	The chemical reactions and pathways involving cell wall chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues, found in the walls of cells.	tmpzr1t_l9r_go_relaxed.owl	cell wall chitin metabolism													biological_process											owl:Class	
GO:0043470	biolink:NamedThing	regulation of carbohydrate catabolic process	Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of carbohydrates.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0060512	biolink:NamedThing	prostate gland morphogenesis	The process in which the anatomical structures of a prostate gland are generated and organized.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0071580	biolink:NamedThing	regulation of zinc ion transmembrane transport	Any process that modulates the frequency, rate or extent of the directed movement of zinc ions (Zn2+) from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	regulation of zinc ion membrane transport							mah	2010-01-28T03:05:53Z					biological_process											owl:Class	
GO:1905817	biolink:NamedThing	positive regulation of dorsal/ventral axon guidance	Any process that activates or increases the frequency, rate or extent of dorsal/ventral axon guidance.	tmpzr1t_l9r_go_relaxed.owl	activation of dorsal/ventral axon pathfinding|up-regulation of dorsal/ventral axon guidance|upregulation of dorsoventral axon guidance|activation of dorsal/ventral axon guidance|upregulation of dorsal/ventral axon guidance|upregulation of dorsal-ventral axon guidance|upregulation of dorsal/ventral axon pathfinding|up-regulation of dorsal/ventral axon pathfinding|positive regulation of dorsal/ventral axon pathfinding|up regulation of dorsoventral axon guidance|up regulation of dorsal/ventral axon pathfinding|up regulation of dorsal-ventral axon guidance|up-regulation of dorsoventral axon guidance|up-regulation of dorsal-ventral axon guidance|activation of dorsal-ventral axon guidance|activation of dorsoventral axon guidance|positive regulation of dorsoventral axon guidance|up regulation of dorsal/ventral axon guidance|positive regulation of dorsal-ventral axon guidance							hbye	2017-01-12T13:39:01Z					biological_process											owl:Class	
GO:0015847	biolink:NamedThing	putrescine transport	The directed movement of putrescine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Putrescine is 1,4-diaminobutane, the polyamine formed by decarboxylation of ornithine and the metabolic precursor of spermidine and spermine.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0015846	biolink:NamedThing	polyamine transport	The directed movement of polyamines, organic compounds containing two or more amino groups, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0038149	biolink:NamedThing	C-C motif chemokine 2 receptor activity	Combining with the C-C motif chemokine 2 (CCL2) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	CCL2 receptor activity							bf	2012-05-11T11:37:16Z					molecular_function											owl:Class	
GO:0016493	biolink:NamedThing	C-C chemokine receptor activity	Combining with a C-C chemokine and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. C-C chemokines do not have an amino acid between the first two cysteines of the characteristic four-cysteine motif.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0035934	biolink:NamedThing	corticosterone secretion	The regulated release of corticosterone into the circulatory system. Corticosterone is a 21-carbon steroid hormone of the corticosteroid type produced in the cortex of the adrenal glands.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-07-20T01:09:31Z					biological_process											owl:Class	
GO:2000343	biolink:NamedThing	positive regulation of chemokine (C-X-C motif) ligand 2 production	Any process that activates or increases the frequency, rate or extent of chemokine (C-X-C motif) ligand 2 production.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of CXCL2 production|positive regulation of MIP-2 production|positive regulation of SCYB2 production|positive regulation of MIP2 production|positive regulation of chemokine (C-C motif) ligand 2 secretion|positive regulation of CCL2 secretion							mah	2011-02-01T11:57:20Z			GO:1904209		biological_process											owl:Class	
GO:2000341	biolink:NamedThing	regulation of chemokine (C-X-C motif) ligand 2 production	Any process that modulates the frequency, rate or extent of chemokine (C-X-C motif) ligand 2 production.	tmpzr1t_l9r_go_relaxed.owl	regulation of MIP2 production|regulation of SCYB2 production|regulation of CCL2 secretion|regulation of chemokine (C-C motif) ligand 2 secretion|regulation of MIP-2 production|chemokine (C-C motif) ligand 2 secretion|regulation of CXCL2 production							mah	2011-02-01T11:57:14Z			GO:0035926|GO:1904207		biological_process											owl:Class	
GO:0036529	biolink:NamedThing	protein deglycation, glyoxal removal	The removal of glyoxal from a glycated protein, to form glycolate and a deglycated protein.	tmpzr1t_l9r_go_relaxed.owl	protein deglycation of glyoxal-glycated protein							bf	2016-08-04T10:41:25Z					biological_process											owl:Class	
GO:1903189	biolink:NamedThing	glyoxal metabolic process	The chemical reactions and pathways involving glyoxal.	tmpzr1t_l9r_go_relaxed.owl	glyoxal metabolism							bf	2014-07-15T10:11:45Z					biological_process											owl:Class	
GO:0006404	biolink:NamedThing	RNA import into nucleus	The import of RNA from the cytoplasm to the nucleus.	tmpzr1t_l9r_go_relaxed.owl	RNA-nucleus import|RNA import into cell nucleus|RNA transport from cytoplasm to nucleus													biological_process											owl:Class	
GO:0050658	biolink:NamedThing	RNA transport	The directed movement of RNA, ribonucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0009875	biolink:NamedThing	pollen-pistil interaction	The interaction between a pollen grain and pistil.	tmpzr1t_l9r_go_relaxed.owl	pollen-gynoecium interaction													biological_process											owl:Class	
GO:0048066	biolink:NamedThing	developmental pigmentation	The developmental process that results in the deposition of coloring matter in an organism, tissue or cell.	tmpzr1t_l9r_go_relaxed.owl	pigmentation during development													biological_process											owl:Class	
GO:0043473	biolink:NamedThing	pigmentation	The accumulation of pigment in an organism, tissue or cell, either by increased deposition or by increased number of cells.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:2000668	biolink:NamedThing	regulation of dendritic cell apoptotic process	Any process that modulates the frequency, rate or extent of dendritic cell apoptotic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of dendritic cell apoptosis							pr	2011-05-09T07:34:16Z					biological_process											owl:Class	
GO:0016807	biolink:NamedThing	cysteine-type carboxypeptidase activity	Catalysis of the hydrolysis of a single C-terminal amino acid residue from a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/19681			MetaCyc:3.4.18.1-RXN|EC:3.4.18.-									molecular_function											owl:Class	
GO:0140194	biolink:NamedThing	negative regulation of adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in heart process	Any process that stops, prevents or reduces the frequency, rate or extent of an adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in some heart process.	tmpzr1t_l9r_go_relaxed.owl								pg	2018-02-15T19:13:02Z					biological_process											owl:Class	
GO:1902182	biolink:NamedThing	shoot apical meristem development	The process whose specific outcome is the progression of a shoot apical meristem over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl	promeristem development|SAM development|primary shoot meristem development							tb	2013-05-30T23:13:21Z					biological_process											owl:Class	
GO:0035025	biolink:NamedThing	positive regulation of Rho protein signal transduction	Any process that activates or increases the frequency, rate or extent of Rho protein signal transduction.	tmpzr1t_l9r_go_relaxed.owl	stimulation of Rho protein signal transduction|up regulation of Rho protein signal transduction|activation of Rho protein signal transduction|up-regulation of Rho protein signal transduction|upregulation of Rho protein signal transduction													biological_process											owl:Class	
GO:0050863	biolink:NamedThing	regulation of T cell activation	Any process that modulates the frequency, rate or extent of T cell activation.	tmpzr1t_l9r_go_relaxed.owl	regulation of T-cell activation|regulation of T lymphocyte activation|regulation of T-lymphocyte activation													biological_process											owl:Class	
GO:0039527	biolink:NamedThing	suppression by virus of host TRAF-mediated signal transduction	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of TRAF-mediated signal transduction in the host.	tmpzr1t_l9r_go_relaxed.owl	suppression by virus of host tumor necrosis factor receptor-associated factor signaling|negative regulation by virus of host TRAF-mediated signal transduction|inhibition of host TRAF-mediated signal transduction by virus							bf	2011-06-22T05:30:41Z					biological_process											owl:Class	
GO:0015347	biolink:NamedThing	sodium-independent organic anion transmembrane transporter activity	Enables the transfer of organic anions from one side of a membrane to the other, in a sodium independent manner.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-9661799|Reactome:R-HSA-879594|Reactome:R-HSA-879562|Reactome:R-HSA-561059|Reactome:R-HSA-879584|Reactome:R-HSA-9661446|Reactome:R-HSA-9661397|Reactome:R-HSA-9661723									molecular_function											owl:Class	
GO:0019708	biolink:NamedThing	peptidyl-glycine cholesteryl ester biosynthesis from peptidyl-glycine	The synthesis of peptidyl-glycine cholest-5-en-3-beta-ol ester at the carboxy-terminus of autolytically cleaved proteins.	tmpzr1t_l9r_go_relaxed.owl	peptidyl-glycine cholesteryl ester anabolism from peptidyl-glycine|peptidyl-glycine cholesteryl ester formation from peptidyl-glycine|peptidyl-glycine cholesteryl ester synthesis from peptidyl-glycine				RESID:AA0309									biological_process											owl:Class	
GO:0006501	biolink:NamedThing	C-terminal protein lipidation	The covalent attachment of a lipid group to the carboxy-terminus of a protein.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0075031	biolink:NamedThing	positive regulation of formation of symbiont germ tube hook structure for appressorium development	Any process that activates, maintains or increases the frequency, rate or extent of symbiont germ tube hook structure formation.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of symbiont germ tube hook structure formation on or near host|positive regulation of formation of symbiont germ tube hook structure on or near host|positive regulation of germ tube tip of symbiont on or near the exterior of host													biological_process											owl:Class	
GO:1990529	biolink:NamedThing	glycosylphosphatidylinositol-mannosyltransferase I complex	A protein complex that is involved in the transfer of the four mannoses in the GPI-anchor precursor. In yeast S. cerevisiae this complex consists of Pbn1p and Gpi14p and in rat this complex consists of PIG-X and PIG-M.	tmpzr1t_l9r_go_relaxed.owl	GPI-MT-I complex							rb	2014-11-06T01:02:31Z					cellular_component											owl:Class	
GO:1901642	biolink:NamedThing	nucleoside transmembrane transport	The directed movement of nucleoside across a membrane.	tmpzr1t_l9r_go_relaxed.owl	nucleoside membrane transport					Note that this term is not intended for use in annotating lateral movement within membranes.		pr	2012-11-16T13:32:01Z					biological_process											owl:Class	
GO:0036280	biolink:NamedThing	cellular response to L-canavanine	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-canavanine stimulus. L-canavanine is L-homoserine substituted at oxygen with a guanidino (carbamimidamido) group.	tmpzr1t_l9r_go_relaxed.owl								bf	2012-07-11T11:09:37Z					biological_process											owl:Class	
GO:1902923	biolink:NamedThing	poly(3-hydroxyvalerate) biosynthetic process	The chemical reactions and pathways resulting in the formation of poly(3-hydroxyvalerate).	tmpzr1t_l9r_go_relaxed.owl	poly(3-hydroxyvalerate) anabolism|poly(3-hydroxyvalerate) formation|poly(3-hydroxyvalerate) synthesis|poly(3-hydroxyvalerate) biosynthesis							tt	2014-04-21T19:14:02Z					biological_process											owl:Class	
GO:1902921	biolink:NamedThing	poly(hydroxyvalerate) biosynthetic process	The chemical reactions and pathways resulting in the formation of poly(hydroxyvalerate).	tmpzr1t_l9r_go_relaxed.owl	poly(hydroxyvalerate) anabolism|poly(hydroxyvalerate) biosynthesis|poly(hydroxyvalerate) synthesis|poly(hydroxyvalerate) formation							tt	2014-04-21T19:12:38Z					biological_process											owl:Class	
GO:0002679	biolink:NamedThing	respiratory burst involved in defense response	A phase of elevated metabolic activity, during which oxygen consumption increases made as part of a defense response ; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0002252	biolink:NamedThing	immune effector process	Any process of the immune system that executes a component of an immune response. An effector immune process takes place after its activation.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/18737												biological_process											owl:Class	
GO:1902222	biolink:NamedThing	erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process	The chemical reactions and pathways resulting in the breakdown of erythrose 4-phosphate/phosphoenolpyruvate family amino acid.	tmpzr1t_l9r_go_relaxed.owl	erythrose 4-phosphate/phosphoenolpyruvate family amino acid breakdown|erythrose 4-phosphate/phosphoenolpyruvate family amino acid degradation|erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolism							pr	2013-06-13T10:37:43Z					biological_process											owl:Class	
GO:0048169	biolink:NamedThing	regulation of long-term neuronal synaptic plasticity	A process that modulates long-term neuronal synaptic plasticity, the ability of neuronal synapses to change long-term as circumstances require. Long-term neuronal synaptic plasticity generally involves increase or decrease in actual synapse numbers.	tmpzr1t_l9r_go_relaxed.owl						Note that the syntax of the definition of this term is different from the usual regulation syntax because it describes regulation of a trait rather than regulation of a process.								biological_process											owl:Class	
GO:0048168	biolink:NamedThing	regulation of neuronal synaptic plasticity	A process that modulates neuronal synaptic plasticity, the ability of neuronal synapses to change as circumstances require. They may alter function, such as increasing or decreasing their sensitivity, or they may increase or decrease in actual numbers.	tmpzr1t_l9r_go_relaxed.owl						Note that the syntax of the definition of this term is different from the usual regulation syntax because it describes regulation of a trait rather than regulation of a process.								biological_process											owl:Class	
GO:0015459	biolink:NamedThing	potassium channel regulator activity	Binds to and modulates the activity of a potassium channel.	tmpzr1t_l9r_go_relaxed.owl	potassium channel gating activity													molecular_function											owl:Class	
GO:0030923	biolink:NamedThing	metal incorporation into metallo-oxygen cluster	The formation of a cluster of several metal atoms, including manganese or calcium, with one or more bridging (mu-bond) oxygen atoms; amino acids residues in proteins that may ligate the metal oxygen cluster are histidine, aspartate, and glutamate.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0009224	biolink:NamedThing	CMP biosynthetic process	The chemical reactions and pathways resulting in the formation of CMP, cytidine monophosphate.	tmpzr1t_l9r_go_relaxed.owl	CMP anabolism|CMP synthesis|CMP formation|CMP biosynthesis													biological_process											owl:Class	
GO:0046596	biolink:NamedThing	regulation of viral entry into host cell	Any process that modulates the frequency, rate or extent of the viral entry into the host cell.	tmpzr1t_l9r_go_relaxed.owl	viral escort protein|regulation of viral penetration into host cell													biological_process											owl:Class	
GO:1904967	biolink:NamedThing	regulation of monopolar spindle attachment to meiosis I kinetochore	Any process that modulates the frequency, rate or extent of attachment of spindle microtubules to kinetochore involved in homologous chromosome segregation.	tmpzr1t_l9r_go_relaxed.owl	regulation of monopolar attachment|regulation of attachment of spindle microtubules to kinetochore involved in meiosis I|regulation of sister kinetochore mono-orientation|regulation of attachment of spindle microtubules to kinetochore during meiosis I|repair of merotelic kinetochore attachment defect, meiosis I|regulation of attachment of spindle microtubules to kinetochore involved in homologous chromosome segregation|correction of merotelic kinetochore attachment, meiosis I	https://github.com/geneontology/go-ontology/issues/18815						mah	2016-02-15T15:19:12Z			GO:0090699		biological_process											owl:Class	
GO:0008015	biolink:NamedThing	blood circulation	The flow of blood through the body of an animal, enabling the transport of nutrients to the tissues and the removal of waste products.	tmpzr1t_l9r_go_relaxed.owl	hemolymph circulation											GO:0070261		biological_process											owl:Class	
GO:0048257	biolink:NamedThing	3'-flap endonuclease activity	Catalysis of the cleavage of a 3' flap structure in DNA, but not other DNA structures; processes the 3' ends of Okazaki fragments in lagging strand DNA synthesis.	tmpzr1t_l9r_go_relaxed.owl	3' flap endonuclease activity													molecular_function											owl:Class	
GO:0016889	biolink:NamedThing	endodeoxyribonuclease activity, producing 3'-phosphomonoesters	Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acids by creating internal breaks to yield 3'-phosphomonoesters.	tmpzr1t_l9r_go_relaxed.owl	endodeoxyribonuclease activity, producing other than 5'-phosphomonoesters				EC:3.1.22.-									molecular_function											owl:Class	
GO:0061247	biolink:NamedThing	mesonephric glomerular mesangium development	The process whose specific outcome is the progression of the mesonephric glomerular mesangium over time, from its formation to the mature structure. The mesonephric glomerular mesangium is the thin membrane connective tissue composed of mesangial cells in the mesonephros, which helps to support the capillary loops in a renal glomerulus.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-08-30T12:59:25Z					biological_process											owl:Class	
GO:0072109	biolink:NamedThing	glomerular mesangium development	The process whose specific outcome is the progression of the glomerular mesangium over time, from its formation to the mature structure. The glomerular mesangium is the thin membrane connective tissue composed of mesangial cells, which helps to support the capillary loops in a renal glomerulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-02-22T10:35:24Z					biological_process											owl:Class	
GO:1904151	biolink:NamedThing	positive regulation of microglial cell mediated cytotoxicity	Any process that activates or increases the frequency, rate or extent of microglial cell mediated cytotoxicity.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of microglial cell mediated cytotoxicity|upregulation of microglial cell mediated cytotoxicity|activation of microglial cell mediated cytotoxicity|up regulation of microglial cell mediated cytotoxicity							nc	2015-04-15T08:05:42Z					biological_process											owl:Class	
GO:0036421	biolink:NamedThing	extrinsic component of external side of mycolate outer membrane	The component of mycolate membrane consisting of gene products and protein complexes that are loosely bound to its external surface, but not integrated into the hydrophobic region.	tmpzr1t_l9r_go_relaxed.owl	extrinsic to external side of mycolate outer membrane|extrinsic to external side of MOM|extrinsic to external side of mycomembrane							bf	2013-09-05T20:23:45Z					cellular_component											owl:Class	
GO:0031242	biolink:NamedThing	extrinsic component of external side of cell outer membrane	The component of a cell outer membrane consisting of gene products and protein complexes that are loosely bound to its external surface, but not integrated into the hydrophobic region.	tmpzr1t_l9r_go_relaxed.owl	extrinsic to external side of outer membrane|extrinsic to external side of cell outer membrane|extrinsic to external leaflet of cell outer membrane													cellular_component											owl:Class	
GO:0046323	biolink:NamedThing	glucose import	The directed movement of the hexose monosaccharide glucose into a cell or organelle.	tmpzr1t_l9r_go_relaxed.owl	glucose uptake				Wikipedia:Glucose_uptake									biological_process											owl:Class	
GO:1904659	biolink:NamedThing	glucose transmembrane transport	The process in which glucose is transported across a membrane.	tmpzr1t_l9r_go_relaxed.owl	glucose transport							vw	2015-09-04T17:20:16Z			GO:0015758		biological_process											owl:Class	
GO:1905206	biolink:NamedThing	positive regulation of hydrogen peroxide-induced cell death	Any process that activates or increases the frequency, rate or extent of cell death in response to hydrogen peroxide.	tmpzr1t_l9r_go_relaxed.owl	activation of cell death in response to hydrogen peroxide|positive regulation of cell death in response to hydrogen peroxide|activation of hydrogen peroxide-mediated cell death|positive regulation of hydrogen peroxide-mediated cell death|up regulation of hydrogen peroxide-mediated cell death|positive regulation of cell death in response to H2O2|upregulation of hydrogen peroxide-mediated cell death|up regulation of cell death in response to H2O2|up-regulation of cell death in response to hydrogen peroxide|upregulation of cell death in response to hydrogen peroxide|activation of cell death in response to H2O2|up-regulation of cell death in response to H2O2|upregulation of cell death in response to H2O2|up regulation of cell death in response to hydrogen peroxide|up-regulation of hydrogen peroxide-mediated cell death							bc	2016-05-20T13:13:39Z					biological_process											owl:Class	
GO:1900629	biolink:NamedThing	methanophenazine metabolic process	The chemical reactions and pathways involving methanophenazine.	tmpzr1t_l9r_go_relaxed.owl	methanophenazine metabolism							tt	2012-05-21T06:12:07Z					biological_process											owl:Class	
GO:0000102	biolink:NamedThing	L-methionine secondary active transmembrane transporter activity	Enables the transfer of L-methionine from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters.	tmpzr1t_l9r_go_relaxed.owl	L-methionine porter activity													molecular_function											owl:Class	
GO:0050607	biolink:NamedThing	mycothiol-dependent formaldehyde dehydrogenase activity	Catalysis of the reaction: formaldehyde + mycothiol + NAD+ = S-formylmycothiol + NADH + H+.	tmpzr1t_l9r_go_relaxed.owl	formaldehyde:NAD+ oxidoreductase (mycothiol-formylating)|NAD/factor-dependent formaldehyde dehydrogenase activity				MetaCyc:1.2.1.66-RXN|EC:1.1.1.306|RHEA:28502									molecular_function											owl:Class	
GO:0030237	biolink:NamedThing	female sex determination	The specification of female sex of an individual organism.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0007530	biolink:NamedThing	sex determination	Any process that establishes and transmits the specification of sexual status of an individual organism.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Sex-determination_system									biological_process											owl:Class	
GO:0042443	biolink:NamedThing	phenylethylamine metabolic process	The chemical reactions and pathways involving phenylethylamine, an amine with pharmacological properties similar to those of amphetamine, occurs naturally as a neurotransmitter in the brain, and is present in chocolate and oil of bitter almonds.	tmpzr1t_l9r_go_relaxed.owl	phenylethylamine metabolism													biological_process											owl:Class	
GO:0001725	biolink:NamedThing	stress fiber	A contractile actin filament bundle that consists of short actin filaments with alternating polarity, cross-linked by alpha-actinin and possibly other actin bundling proteins, and with myosin present in a periodic distribution along the fiber.	tmpzr1t_l9r_go_relaxed.owl	stress fibre|actin cable													cellular_component											owl:Class	
GO:0050305	biolink:NamedThing	strombine dehydrogenase activity	Catalysis of the reaction: N-(carboxymethyl)-D-alanine + H(2)O + NAD(+) = glycine + H(+) + NADH + pyruvate.	tmpzr1t_l9r_go_relaxed.owl	N-(carboxymethyl)-D-alanine: NAD+ oxidoreductase activity|N-(carboxymethyl)-D-alanine:NAD+ oxidoreductase (glycine-forming)|strombine[N-(carboxymethyl)-D-alanine]dehydrogenase activity				KEGG_REACTION:R00368|RHEA:14061|MetaCyc:STROMBINE-DEHYDROGENASE-RXN|EC:1.5.1.22									molecular_function											owl:Class	
GO:0015842	biolink:NamedThing	aminergic neurotransmitter loading into synaptic vesicle	The active transport of aminergic neurotransmitters into a synaptic vesicle.  This import is fuelled by an electrochemical gradient across the vesicle membrane, established by the action proton pumps.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0098700	biolink:NamedThing	neurotransmitter loading into synaptic vesicle	The active transport of neurotransmitters into a synaptic vesicle.  This import is fuelled by an electrochemical gradient across the vesicle membrane, established by the action of proton pumps.	tmpzr1t_l9r_go_relaxed.owl	synaptic vesicle neurotransmitter loading|neurotransmitter uptake into synaptic vesicle|neurotransmitter import into synaptic vesicle													biological_process											owl:Class	
GO:0097007	biolink:NamedThing	4,8,12-trimethyltrideca-1,3,7,11-tetraene synthase activity	Catalysis of the reaction: (EE)-geranyllinalool + NADPH + O2 = 4,8,12-trimethyl-1,3,7,11-tridecatetraene + NADP+ + 2 H2O. It is unknown whether this reaction proceeds by the direct release of the 4-carbon compound but-1-en-3-one, or whether the substrate is first degraded to C18-farnesylacetone and then cleaved to produce 4,8,12-trimethyl-1,3,7,11-tridecatetraene (TMTT) and acetone.	tmpzr1t_l9r_go_relaxed.owl	4,8,12-trimethyl-1,3,7,11-tridecatetraene synthase activity|TMTT synthase activity				RHEA:13545|MetaCyc:RXN-8620			pr	2011-03-16T04:37:20Z					molecular_function											owl:Class	
GO:0031102	biolink:NamedThing	neuron projection regeneration	The regrowth of neuronal processes such as axons or dendrites in response to their loss or damage.	tmpzr1t_l9r_go_relaxed.owl	neurite regeneration													biological_process											owl:Class	
GO:0032675	biolink:NamedThing	regulation of interleukin-6 production	Any process that modulates the frequency, rate, or extent of interleukin-6 production.	tmpzr1t_l9r_go_relaxed.owl	regulation of interleukin-6 biosynthetic process|regulation of IL-6 production											GO:0045408		biological_process											owl:Class	
GO:0047252	biolink:NamedThing	beta-mannosylphosphodecaprenol-mannooligosaccharide 6-mannosyltransferase activity	Catalysis of the reaction: (1->6)-alpha-D-mannosyloligosaccharide + beta-D-mannosylphosphodecaprenol = (1->6)-alpha-D-mannosyl-(1->6)-alpha-D-mannosyl-oligosaccharide + decaprenol phosphate.	tmpzr1t_l9r_go_relaxed.owl	mannosylphospholipid-methylmannoside alpha-1,6-mannosyltransferase activity|beta-D-mannosylphosphodecaprenol:1,6-alpha-D-mannosyloligosaccharide 1,6-alpha-D-mannosyltransferase activity				EC:2.4.1.199|MetaCyc:2.4.1.199-RXN									molecular_function											owl:Class	
GO:0120062	biolink:NamedThing	positive regulation of gastric emptying	Any process that increases the frequency, rate or extent of any gastric emptying process, the process in which the liquid and liquid-suspended solid contents of the stomach exit through the pylorus into the duodenum.	tmpzr1t_l9r_go_relaxed.owl								krc	2017-06-13T21:55:08Z					biological_process											owl:Class	
GO:0090092	biolink:NamedThing	regulation of transmembrane receptor protein serine/threonine kinase signaling pathway	Any process that modulates the rate, frequency, or extent of the series of molecular signals generated as a consequence of a transmembrane receptor serine/threonine kinase binding to its physiological ligand.	tmpzr1t_l9r_go_relaxed.owl	regulation of transmembrane receptor protein serine/threonine kinase signalling pathway							tb	2009-11-04T11:46:40Z					biological_process											owl:Class	
GO:0018679	biolink:NamedThing	dibenzothiophene-5,5-dioxide monooxygenase activity	Catalysis of the reaction: dibenzothiophene-5,5-dioxide + O2 + 2 NADH + H+ = 2 NAD+ + H2O + 2'-hydroxybiphenyl-2-sulfinate.	tmpzr1t_l9r_go_relaxed.owl					EC:1.14.14.-|UM-BBD_reactionID:r0235|MetaCyc:RXN-623									molecular_function											owl:Class	
GO:0044861	biolink:NamedThing	protein transport into plasma membrane raft	The directed movement of a protein into a plasma membrane raft.	tmpzr1t_l9r_go_relaxed.owl								jl	2014-07-23T16:26:29Z					biological_process											owl:Class	
GO:0044860	biolink:NamedThing	protein localization to plasma membrane raft	A process in which a protein is transported to, or maintained in, a location within a plasma membrane raft.	tmpzr1t_l9r_go_relaxed.owl								jl	2014-07-23T16:25:01Z					biological_process											owl:Class	
GO:0140420	biolink:NamedThing	heme import into cell	The directed movement of a heme from outside of a cell into a cell. This may occur via transport across the plasma membrane or via endocytosis.	tmpzr1t_l9r_go_relaxed.owl	heme assimilation	https://github.com/geneontology/go-ontology/issues/18671						pg	2020-01-30T13:10:07Z					biological_process											owl:Class	
GO:0015886	biolink:NamedThing	heme transport	The directed movement of heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	haem transport													biological_process											owl:Class	
GO:0071972	biolink:NamedThing	peptidoglycan L,D-transpeptidase activity	Catalysis of the reaction: 2 a peptidoglycan dimer (tetrapeptide) + 3 H2O = a peptidoglycan tetramer with L,D cross-links (L-Lys-D-Asn-L-Lys) + di-trans,poly-cis-undecaprenyl diphosphate + 4 D-alanine.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-11349			mah	2010-10-18T04:36:19Z					molecular_function											owl:Class	
GO:0080121	biolink:NamedThing	AMP transport	The directed movement of AMP, adenosine monophosphate, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	adenosine monophosphate transport							dhl	2009-04-28T04:01:37Z					biological_process											owl:Class	
GO:0097740	biolink:NamedThing	paraflagellar rod	A large lattice-like axial structure found in some flagellated protists which extends alongside the axoneme. Protein components of the paraflagellar rod are likely implicated, among other, in adenine nucleotide signalling and metabolism, and in calcium signalling.	tmpzr1t_l9r_go_relaxed.owl	PFR							pr	2016-10-19T11:30:08Z					cellular_component											owl:Class	
GO:0045732	biolink:NamedThing	positive regulation of protein catabolic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds.	tmpzr1t_l9r_go_relaxed.owl	up regulation of protein catabolic process|up-regulation of protein catabolic process|positive regulation of protein degradation|positive regulation of protein breakdown|activation of protein catabolic process|stimulation of protein catabolic process|upregulation of protein catabolic process|positive regulation of protein catabolism													biological_process											owl:Class	
GO:0010326	biolink:NamedThing	methionine-oxo-acid transaminase activity	Catalysis of the reaction: methionine + a 2-oxo acid = 2-oxo-4-methylthiobutanoate + an amino acid.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-2201									molecular_function											owl:Class	
GO:0002307	biolink:NamedThing	CD8-positive, alpha-beta regulatory T cell differentiation	The process in which a precursor cell type acquires the specialized features of a CD8-positive, alpha-beta regulatory T cell.	tmpzr1t_l9r_go_relaxed.owl	CD8-positive, alpha-beta regulatory T cell development|CD8-positive, alpha-beta regulatory T-lymphocyte differentiation|CD8-positive, alpha-beta regulatory T lymphocyte differentiation|CD8-positive, alpha-beta regulatory T-cell differentiation					Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.								biological_process											owl:Class	
GO:0043374	biolink:NamedThing	CD8-positive, alpha-beta T cell differentiation	The process in which a relatively unspecialized T cell acquires specialized features of a mature CD8-positive, alpha-beta T cell.	tmpzr1t_l9r_go_relaxed.owl	CD8-positive, alpha-beta T lymphocyte differentiation|CD8-positive, alpha-beta T-cell differentiation|CD8-positive, alpha-beta T cell development|CD8-positive, alpha-beta T-lymphocyte differentiation					Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.								biological_process											owl:Class	
GO:0031113	biolink:NamedThing	regulation of microtubule polymerization	Any process that modulates the frequency, rate or extent of microtubule polymerization.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0032271	biolink:NamedThing	regulation of protein polymerization	Any process that modulates the frequency, rate or extent of the process of creating protein polymers.	tmpzr1t_l9r_go_relaxed.owl	regulation of protein polymerisation													biological_process											owl:Class	
GO:0033467	biolink:NamedThing	CMP-keto-3-deoxy-D-manno-octulosonic acid metabolic process	The chemical reactions and pathways involving CMP-keto-3-deoxy-D-manno-octulosonic acid, a substance composed of the acidic sugar 3-deoxy-D-manno-octulosonic acid in glycosidic linkage with cytidine monophosphate.	tmpzr1t_l9r_go_relaxed.owl	CMP-ketodeoxyoctanoate metabolic process|CMP-keto-3-deoxy-D-manno-octulosonic acid metabolism|CMP-KDO metabolic process													biological_process											owl:Class	
GO:0045472	biolink:NamedThing	response to ether	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ether stimulus.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0016316	biolink:NamedThing	phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity	Catalysis of the reaction: 1-phosphatidyl-myo-inositol 3,4-bisphosphate + H2O = 1-phosphatidyl-1D-myo-inositol 3-phosphate + phosphate.	tmpzr1t_l9r_go_relaxed.owl	1-phosphatidyl-1D-myo-inositol-3,4-bisphosphate 4-phosphohydrolase activity|inositol polyphosphate 4-phosphatase type II activity				Reactome:R-HSA-1676162|EC:3.1.3.66|MetaCyc:3.1.3.66-RXN|Reactome:R-HSA-1676164							GO:0004440		molecular_function											owl:Class	
GO:1903170	biolink:NamedThing	negative regulation of calcium ion transmembrane transport	Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion transmembrane transport.	tmpzr1t_l9r_go_relaxed.owl	down regulation of calcium ion transmembrane transport|down-regulation of calcium ion transmembrane transport|down-regulation of transmembrane calcium transport|downregulation of calcium ion membrane transport|inhibition of calcium ion transmembrane transport|negative regulation of transmembrane calcium transport|inhibition of transmembrane calcium transport|down-regulation of calcium ion membrane transport|negative regulation of calcium ion membrane transport|inhibition of calcium ion membrane transport|down regulation of calcium ion membrane transport|downregulation of calcium ion transmembrane transport|downregulation of transmembrane calcium transport|down regulation of transmembrane calcium transport					human HRC regulates RYR2 and thus regulates transmembrane transport of calcium from SR to cytosol		rl	2014-07-11T17:09:32Z					biological_process											owl:Class	
GO:1902140	biolink:NamedThing	response to inositol	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an inositol stimulus.	tmpzr1t_l9r_go_relaxed.owl								al	2013-05-21T13:42:10Z					biological_process											owl:Class	
GO:2000609	biolink:NamedThing	regulation of thyroid hormone generation	Any process that modulates the frequency, rate or extent of thyroid hormone generation.	tmpzr1t_l9r_go_relaxed.owl								yaf	2011-04-18T10:12:14Z					biological_process											owl:Class	
GO:1902176	biolink:NamedThing	negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway	Any process that stops, prevents or reduces the frequency, rate or extent of an oxidative stress-induced intrinsic apoptotic signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	down regulation of intrinsic apoptotic signaling pathway in response to oxidative stress|inhibition of intrinsic apoptotic signaling pathway in response to oxidative stress|negative regulation of intrinsic apoptotic signaling pathway in response to oxidative stress|downregulation of intrinsic apoptotic signaling pathway in response to oxidative stress|down-regulation of intrinsic apoptotic signaling pathway in response to oxidative stress							pr	2013-05-29T18:30:05Z					biological_process											owl:Class	
GO:2001243	biolink:NamedThing	negative regulation of intrinsic apoptotic signaling pathway	Any process that stops, prevents or reduces the frequency, rate or extent of intrinsic apoptotic signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of intrinsic apoptotic signalling pathway|negative regulation of mitochondrial-mediated apoptotic pathway|negative regulation of intrinsic apoptotic pathway|negative regulation of intrinsic apoptosis							pr	2011-11-24T01:36:03Z					biological_process											owl:Class	
GO:1902137	biolink:NamedThing	(-)-secoisolariciresinol catabolic process	The chemical reactions and pathways resulting in the breakdown of (-)-secoisolariciresinol.	tmpzr1t_l9r_go_relaxed.owl	(-)-secoisolariciresinol catabolism|(-)-secoisolariciresinol degradation|(-)-secoisolariciresinol breakdown							ms	2013-05-21T08:50:24Z					biological_process											owl:Class	
GO:0006895	biolink:NamedThing	Golgi to endosome transport	The directed movement of substances from the Golgi to early sorting endosomes. Clathrin vesicles transport substances from the trans-Golgi to endosomes.	tmpzr1t_l9r_go_relaxed.owl	Golgi to endosome vesicle-mediated transport|trans-Golgi to endosome transport|TGN to endosome transport											GO:0048218		biological_process											owl:Class	
GO:0006892	biolink:NamedThing	post-Golgi vesicle-mediated transport	The directed movement of substances from the Golgi to other parts of the cell, including organelles and the plasma membrane, mediated by small transport vesicles.	tmpzr1t_l9r_go_relaxed.owl	post-Golgi transport													biological_process											owl:Class	
GO:0033423	biolink:NamedThing	CCA codon-amino acid adaptor activity	A triplet codon-amino acid adaptor activity that recognizes a CCA codon.	tmpzr1t_l9r_go_relaxed.owl	proline tRNA					Note that in the standard genetic code, CCA codes for proline.								molecular_function											owl:Class	
GO:0120048	biolink:NamedThing	U6 snRNA (adenine-(43)-N(6))-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + adenine(43) in U6 snRNA = S-adenosyl-L-homocysteine + N(6)-methyladenine(43) in U6 snRNA.	tmpzr1t_l9r_go_relaxed.owl								krc	2017-06-02T20:37:40Z					molecular_function											owl:Class	
GO:1905546	biolink:NamedThing	cellular response to phenylpropanoid	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a phenylpropanoid stimulus.	tmpzr1t_l9r_go_relaxed.owl								sl	2016-10-11T19:54:58Z					biological_process											owl:Class	
GO:0002630	biolink:NamedThing	positive regulation of proteolysis associated with antigen processing and presentation	Any process that activates or increases the frequency, rate, or extent of proteolysis associated with antigen processing and presentation.	tmpzr1t_l9r_go_relaxed.owl	upregulation of proteolysis associated with antigen processing and presentation|up regulation of proteolysis associated with antigen processing and presentation|up-regulation of proteolysis associated with antigen processing and presentation|stimulation of proteolysis associated with antigen processing and presentation|activation of proteolysis associated with antigen processing and presentation													biological_process											owl:Class	
GO:0002585	biolink:NamedThing	positive regulation of antigen processing and presentation of peptide antigen	Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of peptide antigen.	tmpzr1t_l9r_go_relaxed.owl	upregulation of antigen processing and presentation of peptide antigen|up-regulation of antigen processing and presentation of peptide antigen|positive regulation of peptide antigen processing and presentation|stimulation of antigen processing and presentation of peptide antigen|up regulation of antigen processing and presentation of peptide antigen|activation of antigen processing and presentation of peptide antigen													biological_process											owl:Class	
GO:1903974	biolink:NamedThing	positive regulation of cellular response to macrophage colony-stimulating factor stimulus	Any process that activates or increases the frequency, rate or extent of cellular response to macrophage colony-stimulating factor stimulus.	tmpzr1t_l9r_go_relaxed.owl	up regulation of cellular response to M-CSF stimulus|positive regulation of cellular response to macrophage colony-stimulating factor|upregulation of cellular response to M-CSF stimulus|upregulation of cellular response to macrophage colony-stimulating factor|upregulation of cellular response to macrophage colony-stimulating factor stimulus|up-regulation of cellular response to M-CSF stimulus|activation of cellular response to macrophage colony-stimulating factor|up-regulation of cellular response to macrophage colony-stimulating factor|activation of cellular response to macrophage colony-stimulating factor stimulus|up regulation of cellular response to macrophage colony-stimulating factor stimulus|up-regulation of cellular response to macrophage colony-stimulating factor stimulus|positive regulation of cellular response to M-CSF stimulus|up regulation of cellular response to macrophage colony-stimulating factor|activation of cellular response to M-CSF stimulus							nc	2015-03-02T14:50:25Z					biological_process											owl:Class	
GO:2000314	biolink:NamedThing	negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation	Any process that stops, prevents or reduces the frequency, rate or extent of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of fibroblast growth factor receptor signalling pathway involved in neural plate anterior/posterior pattern formation							vk	2011-01-18T10:26:56Z					biological_process											owl:Class	
GO:0060186	biolink:NamedThing	outer ear emergence	The growth of the outer ear.	tmpzr1t_l9r_go_relaxed.owl	outer ear growth|ear extroversion|ear elevation													biological_process											owl:Class	
GO:1904556	biolink:NamedThing	L-tryptophan transmembrane transport	The directed movement of L-tryptophan across a membrane.	tmpzr1t_l9r_go_relaxed.owl								pr	2015-08-14T14:21:13Z					biological_process											owl:Class	
GO:0019966	biolink:NamedThing	interleukin-1 binding	Binding to interleukin-1.	tmpzr1t_l9r_go_relaxed.owl	IL-1 binding													molecular_function											owl:Class	
GO:2000109	biolink:NamedThing	regulation of macrophage apoptotic process	Any process that modulates the frequency, rate or extent of macrophage apoptotic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of activation-induced cell death|regulation of macrophage apoptosis|regulation of AICD							mah	2010-09-15T01:44:15Z					biological_process											owl:Class	
GO:0035936	biolink:NamedThing	testosterone secretion	The regulated release of testosterone into the circulatory system. Testosterone is an androgen having 17beta-hydroxy and 3-oxo groups, together with unsaturation at C-4-C-5.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-07-20T01:13:13Z					biological_process											owl:Class	
GO:0035714	biolink:NamedThing	cellular response to nitrogen dioxide	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrogen dioxide (NO2) stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to NO2							bf	2011-03-02T03:16:37Z					biological_process											owl:Class	
GO:0043296	biolink:NamedThing	apical junction complex	A functional unit located near the cell apex at the points of contact between epithelial cells, which in vertebrates is composed of the tight junction, the zonula adherens, and desmosomes and in some invertebrates, such as Drosophila, is composed of the subapical complex (SAC), the zonula adherens and the septate junction. Functions in the regulation of cell polarity, tissue integrity and intercellular adhesion and permeability.	tmpzr1t_l9r_go_relaxed.owl	apical cell junction complex|apical junction													cellular_component											owl:Class	
GO:1901838	biolink:NamedThing	positive regulation of transcription of nucleolar large rRNA by RNA polymerase I	Any process that activates or increases the frequency, rate or extent of transcription of nuclear large rRNA mediated by RNA polymerase I.	tmpzr1t_l9r_go_relaxed.owl	activation of transcription of nuclear rRNA large Pol I transcript|activation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter|positive regulation of transcription of nuclear rRNA large Pol I transcript|up-regulation of transcription of nuclear rRNA large Pol I transcript|upregulation of transcription of nuclear rRNA large Pol I transcript|up regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter|upregulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter|up-regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter|up regulation of transcription of nuclear rRNA large Pol I transcript|positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter							sart	2013-01-23T10:16:36Z					biological_process											owl:Class	
GO:1901836	biolink:NamedThing	regulation of transcription of nucleolar large rRNA by RNA polymerase I	Any process that modulates the frequency, rate or extent of transcription of nuclear large rRNA mediated by RNA polymerase I.	tmpzr1t_l9r_go_relaxed.owl	regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter|regulation of transcription of nuclear rRNA large Pol I transcript							sart	2013-01-23T10:16:27Z					biological_process											owl:Class	
GO:1900367	biolink:NamedThing	positive regulation of defense response to insect	Any process that activates or increases the frequency, rate or extent of defense response to insect.	tmpzr1t_l9r_go_relaxed.owl	up regulation of defense response to insect|upregulation of physiological defense response to insect|up-regulation of physiological defense response to insect|activation of defense response to insect|activation of physiological defense response to insect|positive regulation of physiological defense response to insect|up regulation of physiological defense response to insect|up-regulation of defense response to insect|upregulation of defense response to insect							dhl	2012-04-12T04:44:10Z					biological_process											owl:Class	
GO:1900133	biolink:NamedThing	regulation of renin secretion into blood stream	Any process that modulates the frequency, rate or extent of renin secretion into blood stream.	tmpzr1t_l9r_go_relaxed.owl	regulation of renin release into blood stream							rph	2012-02-27T10:32:01Z					biological_process											owl:Class	
GO:0097041	biolink:NamedThing	phenolic phthiocerol biosynthetic process	The chemical reactions and pathways resulting in the formation of phenolic phthiocerol, a phthiocerol derivative having a 4-hydroxyphenyl substituent at the 29-position.	tmpzr1t_l9r_go_relaxed.owl	phenolic phthiocerol biosynthesis|phenolic phthiocerol formation|phenolic phthiocerol anabolism|phenolphthiocerol biosynthesis|phenolic phthiocerol synthesis							pr	2011-04-15T01:25:59Z					biological_process											owl:Class	
GO:0052921	biolink:NamedThing	acetone-cyanohydrin acetone-lyase (cyanide-forming) activity	Catalysis of the reaction: acetone cyanohydrin = hydrogen cyanide + acetone.	tmpzr1t_l9r_go_relaxed.owl					KEGG_REACTION:R01553|RHEA:11932|EC:4.1.2.46|MetaCyc:ACETONE-CYANHYDRIN-LYASE-RXN									molecular_function											owl:Class	
GO:0052919	biolink:NamedThing	aliphatic (R)-hydroxynitrile lyase activity	Catalysis of the reaction: an aliphatic (R)-hydroxynitrile = an aliphatic aldehyde or ketone + hydrogen cyanide.	tmpzr1t_l9r_go_relaxed.owl	(R)-HNL activity|(R)-hydroxynitrile lyase activity|(R)-oxynitrilase activity				EC:4.1.2.46									molecular_function											owl:Class	
GO:1905934	biolink:NamedThing	negative regulation of cell fate determination	Any process that stops, prevents or reduces the frequency, rate or extent of cell fate determination.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of cell fate determination|downregulation of cell fate determination|inhibition of cell fate determination|down regulation of cell fate determination							bhm	2017-02-09T11:25:30Z					biological_process											owl:Class	
GO:0051491	biolink:NamedThing	positive regulation of filopodium assembly	Any process that activates or increases the frequency, rate or extent of the assembly of a filopodium, a thin, stiff protrusion extended by the leading edge of a motile cell such as a crawling fibroblast or amoeba, or an axonal growth cone.	tmpzr1t_l9r_go_relaxed.owl	upregulation of filopodium formation|positive regulation of filopodia biosynthesis|up regulation of filopodium formation|positive regulation of filopodia formation|stimulation of filopodium formation|positive regulation of filopodium formation|up-regulation of filopodium formation|activation of filopodium formation													biological_process											owl:Class	
GO:0048217	biolink:NamedThing	pectic matrix	The gel-like pectin matrix consists of the interlinked acidic and neutral pectin networks that are further cross-linked by calcium bridges. Pectins consist largely of long chains of mostly galacturonic acid units (typically 1,4 linkages and sometimes methyl esters). Three major pectic polysaccharides (homogalacturonan, rhamnogalacturonan I and rhamnogalacturonan II) are thought to occur in all primary cell walls.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0046447	biolink:NamedThing	terpenoid indole alkaloid metabolic process	The chemical reactions and pathways involving terpenoid indole alkaloids, compounds formed from the condensation of tryptamine (derived from tryptophan) and secologanin (derived from geranyl pyrophosphate).	tmpzr1t_l9r_go_relaxed.owl	terpenoid indole alkaloid metabolism													biological_process											owl:Class	
GO:0003938	biolink:NamedThing	IMP dehydrogenase activity	Catalysis of the reaction: inosine 5'-phosphate + NAD+ + H2O = xanthosine 5'-phosphate + NADH + H+.	tmpzr1t_l9r_go_relaxed.owl	inosine 5'-monophosphate dehydrogenase activity|IMP:NAD+ oxidoreductase activity|inosine monophosphate oxidoreductase activity|inosinate dehydrogenase activity|inosine monophosphate dehydrogenase activity|IMP oxidoreductase activity|inosinic acid dehydrogenase activity|inosine-5'-phosphate dehydrogenase activity				MetaCyc:IMP-DEHYDROG-RXN|RHEA:11708|EC:1.1.1.205|Reactome:R-HSA-73794									molecular_function											owl:Class	
GO:0106253	biolink:NamedThing	positive regulation of DNA strand resection involved in replication fork processing	Any process that activates or increases the frequency, rate or extent of DNA strand resection involved in replication fork processing.	tmpzr1t_l9r_go_relaxed.owl								hjd	2020-02-24T15:31:30Z					biological_process											owl:Class	
GO:0110026	biolink:NamedThing	regulation of DNA strand resection involved in replication fork processing	Any process that modulates the frequency, rate or extent of DNA strand resection involved in replication fork processing.	tmpzr1t_l9r_go_relaxed.owl								kmv	2017-07-05T18:21:06Z					biological_process											owl:Class	
GO:0072388	biolink:NamedThing	flavin adenine dinucleotide biosynthetic process	The chemical reactions and pathways resulting in the formation of flavin adenine dinucleotide, which acts as a coenzyme or prosthetic group of various flavoprotein oxidoreductase enzymes.	tmpzr1t_l9r_go_relaxed.owl	flavin adenine dinucleotide formation|flavin adenine dinucleotide biosynthesis|FAD or FADH2 biosynthetic process|flavin adenine dinucleotide anabolism|flavin adenine dinucleotide synthesis							mah	2010-12-02T04:26:34Z					biological_process											owl:Class	
GO:1904877	biolink:NamedThing	positive regulation of DNA ligase activity	Any process that activates or increases the frequency, rate or extent of DNA ligase activity.	tmpzr1t_l9r_go_relaxed.owl	up regulation of DNA ligase activity|up-regulation of DNA ligase activity|upregulation of DNA ligase activity|activation of DNA ligase activity							rl	2015-12-18T18:35:44Z					biological_process											owl:Class	
GO:1904875	biolink:NamedThing	regulation of DNA ligase activity	Any process that modulates the frequency, rate or extent of DNA ligase activity.	tmpzr1t_l9r_go_relaxed.owl								rl	2015-12-18T18:35:30Z					biological_process											owl:Class	
GO:0097752	biolink:NamedThing	regulation of DNA stability	Any process that modulates the stability of DNA.	tmpzr1t_l9r_go_relaxed.owl								pr	2017-01-24T11:23:01Z					biological_process											owl:Class	
GO:0010711	biolink:NamedThing	negative regulation of collagen catabolic process	Any process that decreases the rate, frequency or extent of collagen catabolism. Collagen catabolism is the proteolytic chemical reactions and pathways resulting in the breakdown of collagen in the extracellular matrix.	tmpzr1t_l9r_go_relaxed.owl	down regulation of collagen catabolic process|negative regulation of collagen breakdown|inhibition of collagen catabolic process|downregulation of collagen catabolic process|negative regulation of collagen degradation|down-regulation of collagen catabolic process|negative regulation of collagen catabolism													biological_process											owl:Class	
GO:0033093	biolink:NamedThing	Weibel-Palade body	A large, elongated, rod-shaped secretory granule characteristic of vascular endothelial cells that contain a number of structurally and functionally distinct proteins, of which the best characterized are von Willebrand factor (VWF) and P-selectin. Weibel-Palade bodies are formed from the trans-Golgi network in a process that depends on VWF, which is densely packed in a highly organized manner, and on coat proteins that remain associated with the granules. Upon cell stimulation, regulated exocytosis releases the contained proteins to the cell surface, where they act in the recruitment of platelets and leukocytes and in inflammatory and vasoactive responses.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Weibel-Palade_body									cellular_component											owl:Class	
GO:0030136	biolink:NamedThing	clathrin-coated vesicle	A vesicle with a coat formed of clathrin connected to the membrane via one of the clathrin adaptor complexes.	tmpzr1t_l9r_go_relaxed.owl					NIF_Subcellular:sao148845161									cellular_component											owl:Class	
GO:0045106	biolink:NamedThing	intermediate filament depolymerization	Disassembly of intermediate filaments by the removal of component monomers from a filament.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0051261	biolink:NamedThing	protein depolymerization	The process in which protein polymers, compounds composed of a large number of component monomers, are broken down. Depolymerization occurs by the successive removal of monomers from an existing poly- or oligomeric protein.	tmpzr1t_l9r_go_relaxed.owl	protein polymer catabolic process|protein polymer degradation|protein polymer catabolism|protein polymer breakdown													biological_process											owl:Class	
GO:1903748	biolink:NamedThing	negative regulation of establishment of protein localization to mitochondrion	Any process that stops, prevents or reduces the frequency, rate or extent of establishment of protein localization to mitochondrion.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of establishment of protein localisation to mitochondrion|inhibition of establishment of protein localization in mitochondrion|down regulation of establishment of protein localization in mitochondrion|downregulation of establishment of protein localization in mitochondrion|inhibition of establishment of protein localisation to mitochondrion|down regulation of establishment of protein localisation to mitochondrion|inhibition of establishment of protein localization to mitochondrion|downregulation of establishment of protein localization to mitochondrion|down regulation of establishment of protein localization to mitochondrion|negative regulation of establishment of protein localisation to mitochondrion|down-regulation of establishment of protein localization to mitochondrion|downregulation of establishment of protein localisation to mitochondrion|down-regulation of establishment of protein localization in mitochondrion|negative regulation of establishment of protein localization in mitochondrion							krc	2014-12-12T22:18:18Z					biological_process											owl:Class	
GO:0005171	biolink:NamedThing	hepatocyte growth factor receptor binding	Binding to an hepatocyte growth factor receptor.	tmpzr1t_l9r_go_relaxed.owl	hepatocyte growth factor|hepatocyte growth factor receptor ligand|HGF receptor binding													molecular_function											owl:Class	
GO:0032490	biolink:NamedThing	detection of molecule of bacterial origin	The series of events in which a stimulus from a molecule of bacterial origin is received and converted into a molecular signal.	tmpzr1t_l9r_go_relaxed.owl	detection of bacterium associated molecule|detection of bacteria associated molecule|detection of bacterial associated molecule													biological_process											owl:Class	
GO:0048871	biolink:NamedThing	multicellular organismal homeostasis	Any process involved in the maintenance of an internal steady state at the level of the multicellular organism.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0019356	biolink:NamedThing	nicotinate nucleotide biosynthetic process from tryptophan	The chemical reactions and pathways resulting in the formation of nicotinate nucleotide from other compounds, including tryptophan.	tmpzr1t_l9r_go_relaxed.owl	nicotinate nucleotide anabolism from tryptophan|nicotinate nucleotide formation from tryptophan|nicotinate nucleotide synthesis from tryptophan													biological_process											owl:Class	
GO:0019357	biolink:NamedThing	nicotinate nucleotide biosynthetic process	The chemical reactions and pathways resulting in the formation of nicotinamide nucleotides, any nucleotide that contains combined nicotinate (pyridine 3-carboxylic acid).	tmpzr1t_l9r_go_relaxed.owl	nicotinate nucleotide synthesis|nicotinate nucleotide anabolism|nicotinate nucleotide formation|nicotinate nucleotide biosynthesis													biological_process											owl:Class	
GO:0050166	biolink:NamedThing	pantoate 4-dehydrogenase activity	Catalysis of the reaction: (R)-pantoate + NAD(+) = (R)-4-dehydropantoate + H(+) + NADH.	tmpzr1t_l9r_go_relaxed.owl	(R)-pantoate:NAD+ 4-oxidoreductase activity|pantoate dehydrogenase activity|panthothenase activity|D-pantoate:NAD+ 4-oxidoreductase activity				RHEA:23000|MetaCyc:PANTOATE-4-DEHYDROGENASE-RXN|EC:1.1.1.106|KEGG_REACTION:R02471									molecular_function											owl:Class	
GO:2000704	biolink:NamedThing	positive regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation	Any process that activates or increases the frequency, rate or extent of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of fibroblast growth factor receptor signalling pathway of ureteric bud formation|positive regulation of fibroblast growth factor receptor signaling pathway of ureteric bud formation|positive regulation of FGF receptor signalling pathway of ureteric bud formation|positive regulation of FGF receptor signaling pathway of ureteric bud formation|positive regulation of FGFR signaling pathway of ureteric bud formation							yaf	2011-05-25T09:48:27Z					biological_process											owl:Class	
GO:0045743	biolink:NamedThing	positive regulation of fibroblast growth factor receptor signaling pathway	Any process that activates or increases the frequency, rate or extent of fibroblast growth factor receptor signaling pathway activity.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of FGF receptor signalling pathway|up regulation of fibroblast growth factor receptor signaling pathway|upregulation of fibroblast growth factor receptor signaling pathway|activation of fibroblast growth factor receptor signaling pathway|positive regulation of FGF receptor signaling pathway|positive regulation of FGFR signaling pathway|stimulation of fibroblast growth factor receptor signaling pathway|up-regulation of fibroblast growth factor receptor signaling pathway													biological_process											owl:Class	
GO:0051463	biolink:NamedThing	negative regulation of cortisol secretion	Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of cortisol from a cell.	tmpzr1t_l9r_go_relaxed.owl	downregulation of cortisol secretion|down regulation of cortisol secretion|down-regulation of cortisol secretion|inhibition of cortisol secretion													biological_process											owl:Class	
GO:0098520	biolink:NamedThing	excitatory neuromuscular junction	The junction between the axon of a motor neuron and a muscle fiber. In response to the arrival of action potentials, the presynaptic button releases molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane of the muscle fiber, leading to a post-synaptic potential responsible for muscle contraction.	tmpzr1t_l9r_go_relaxed.owl								dos	2013-10-14T12:02:51Z					cellular_component											owl:Class	
GO:1900120	biolink:NamedThing	regulation of receptor binding	Any process that modulates the frequency, rate or extent of a protein or other molecule binding to a receptor.	tmpzr1t_l9r_go_relaxed.owl	regulation of receptor ligand							bf	2012-02-22T11:40:53Z					biological_process											owl:Class	
GO:0043012	biolink:NamedThing	regulation of fusion of sperm to egg plasma membrane	Any process that modulates the binding and fusion of a sperm to the oocyte plasma membrane.	tmpzr1t_l9r_go_relaxed.owl	regulation of sperm-oocyte fusion													biological_process											owl:Class	
GO:0021724	biolink:NamedThing	inferior raphe nucleus development	The process whose specific outcome is the progression of the inferior raphe nucleus over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl	inferior central nucleus development|posterior raphe nucleus development													biological_process											owl:Class	
GO:0048857	biolink:NamedThing	neural nucleus development	The biological process whose specific outcome is the progression of a neural nucleus from its initial condition to its mature state. A neural nucleus is an anatomical structure consisting of a discrete aggregate of neuronal soma.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:2000005	biolink:NamedThing	negative regulation of metanephric S-shaped body morphogenesis	Any process that stops, prevents, or reduces the frequency, rate or extent of metanephric S-shaped body morphogenesis.	tmpzr1t_l9r_go_relaxed.owl								jl	2010-07-30T02:14:37Z					biological_process											owl:Class	
GO:0061962	biolink:NamedThing	negative regulation of heme oxygenase activity	Any process that stops, prevents, or reduces the frequency or rate of heme oxygenase activity.	tmpzr1t_l9r_go_relaxed.owl								dph	2018-01-22T20:37:03Z					biological_process											owl:Class	
GO:1901611	biolink:NamedThing	phosphatidylglycerol binding	Binding to phosphatidylglycerol.	tmpzr1t_l9r_go_relaxed.owl								kmv	2012-11-12T21:18:24Z					molecular_function											owl:Class	
GO:1902651	biolink:NamedThing	positive regulation of histone H2A-H2B dimer displacement	Any process that activates or increases the frequency, rate or extent of histone H2A-H2B dimer displacement.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of histone H2A-H2B dimer displacement|activation of histone H2A-H2B dimer displacement|up regulation of histone H2A-H2B dimer displacement|upregulation of histone H2A-H2B dimer displacement							di	2014-01-21T18:19:23Z					biological_process											owl:Class	
GO:0052005	biolink:NamedThing	suppression by symbiont of host ethylene-mediated defense response	Any process in which a symbiont stops, prevents, or reduces the frequency, rate or extent of the ethylene-mediated defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	down regulation by symbiont of host ethylene-mediated defense response|down-regulation by symbiont of host ethylene-mediated defense response|suppression by organism of host ethylene-mediated defense response|negative regulation by organism of defense-related ethylene-mediated signal transduction pathway in other organism involved in symbiotic interaction|inhibition by symbiont of host ethylene-mediated defense response|negative regulation by symbiont of host ethylene-mediated defense response|downregulation by symbiont of host ethylene-mediated defense response|negative regulation by organism of ethylene-mediated defense response of other organism involved in symbiotic interaction|negative regulation by symbiont of defense-related host ethylene-mediated signal transduction pathway											GO:0052268|GO:0052070|GO:0052254		biological_process											owl:Class	
GO:0060232	biolink:NamedThing	delamination	The process of negative regulation of cell adhesion that results in a cell or sheet of cells splitting off from an existing epithelial sheet.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0035563	biolink:NamedThing	positive regulation of chromatin binding	Any process that increases the frequency, rate or extent of chromatin binding. Chromatin binding is the selective interaction with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.	tmpzr1t_l9r_go_relaxed.owl								bf	2010-05-19T10:29:41Z					biological_process											owl:Class	
GO:1901950	biolink:NamedThing	dense core granule transport	The directed movement a dense core granule within a cell.	tmpzr1t_l9r_go_relaxed.owl	dense core vesicle transport					goslim_synapse		pr	2013-02-19T13:00:52Z					biological_process											owl:Class	
GO:2000230	biolink:NamedThing	negative regulation of pancreatic stellate cell proliferation	Any process that stops, prevents, or reduces the frequency, rate or extent of pancreatic stellate cell proliferation.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-11-09T03:45:21Z					biological_process											owl:Class	
GO:0043684	biolink:NamedThing	type IV secretion system complex	A complex of proteins related to those involved in bacterial DNA conjugative transfer, that permits the transfer of DNA or proteins into the extracellular milieu or directly into host cells. In general the type IV complex forms a multisubunit cell-envelope-spanning structure composed of a secretion channel and often a pilus or other surface filament or protein(s).	tmpzr1t_l9r_go_relaxed.owl	type IV protein secretion system complex|T4SS complex													cellular_component											owl:Class	
GO:0072161	biolink:NamedThing	mesenchymal cell differentiation involved in kidney development	The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesenchymal cells of the kidney as it progresses from its formation to the mature state.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-02-26T01:31:49Z					biological_process											owl:Class	
GO:0005497	biolink:NamedThing	androgen binding	Binding to an androgen, a male sex hormone.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0047506	biolink:NamedThing	(deoxy)adenylate kinase activity	Catalysis of the reaction: ATP + dAMP = ADP + dADP.	tmpzr1t_l9r_go_relaxed.owl	ATP:(d)AMP phosphotransferase activity				MetaCyc:DEOXYADENYLATE-KINASE-RXN|EC:2.7.4.11|RHEA:23100									molecular_function											owl:Class	
GO:0004649	biolink:NamedThing	poly(ADP-ribose) glycohydrolase activity	Catalysis of the hydrolysis of poly(ADP-ribose) at glycosidic (1''-2') linkage of ribose-ribose bond to produce free ADP-ribose.	tmpzr1t_l9r_go_relaxed.owl					RHEA:52216|Reactome:R-HSA-8952903|MetaCyc:3.2.1.143-RXN|Reactome:R-HSA-5651828|EC:3.2.1.143									molecular_function											owl:Class	
GO:0099178	biolink:NamedThing	regulation of retrograde trans-synaptic signaling by endocanabinoid	Any process that modulates the frequency, rate or extent of retrograde trans-synaptic signaling by an endocannabinoid.	tmpzr1t_l9r_go_relaxed.owl	regulation of endocannabinoid-mediated retrograde trans-synaptic signaling													biological_process											owl:Class	
GO:1900240	biolink:NamedThing	negative regulation of phenotypic switching	Any process that stops, prevents or reduces the frequency, rate or extent of phenotypic switching.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of phenotypic dimorphism|down regulation of phenotypic dimorphism|downregulation of phenotypic dimorphism|downregulation of phenotypic switching|down regulation of phenotypic switching|down-regulation of phenotypic dimorphism|down-regulation of phenotypic switching|inhibition of phenotypic dimorphism|inhibition of phenotypic switching							di	2012-03-28T01:49:26Z					biological_process											owl:Class	
GO:1900239	biolink:NamedThing	regulation of phenotypic switching	Any process that modulates the frequency, rate or extent of phenotypic switching.	tmpzr1t_l9r_go_relaxed.owl	regulation of phenotypic dimorphism							di	2012-03-28T01:49:16Z					biological_process											owl:Class	
GO:0048817	biolink:NamedThing	negative regulation of hair follicle maturation	Any process that stops, prevents, or reduces the frequency, rate or extent of hair follicle maturation.	tmpzr1t_l9r_go_relaxed.owl	down regulation of hair follicle maturation|inhibition of hair follicle maturation|downregulation of hair follicle maturation|down-regulation of hair follicle maturation													biological_process											owl:Class	
GO:0036119	biolink:NamedThing	response to platelet-derived growth factor	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a platelet-derived growth factor stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to PDGF stimulus|response to platelet-derived growth factor stimulus							bf	2012-02-20T02:48:00Z					biological_process											owl:Class	
GO:0044278	biolink:NamedThing	cell wall disruption in other organism	A process carried out by an organism that results in the breakdown of the cell wall of a second organism.	tmpzr1t_l9r_go_relaxed.owl								jl	2010-01-14T02:01:48Z					biological_process											owl:Class	
GO:0018119	biolink:NamedThing	peptidyl-cysteine S-nitrosylation	The covalent addition of a nitric oxide (NO) group to the sulphur (S) atom of a cysteine residue in a protein, to form peptidyl-S-nitrosyl-L-cysteine.	tmpzr1t_l9r_go_relaxed.owl	protein S-nitrosylation|S-nitrosylation				RESID:AA0230									biological_process											owl:Class	
GO:0010941	biolink:NamedThing	regulation of cell death	Any process that modulates the rate or frequency of cell death. Cell death is the specific activation or halting of processes within a cell so that its vital functions markedly cease, rather than simply deteriorating gradually over time, which culminates in cell death.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0071421	biolink:NamedThing	manganese ion transmembrane transport	A process in which a manganese ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	manganese ion membrane transport|transmembrane manganese transport					Note that this term is not intended for use in annotating lateral movement within membranes.		mah	2009-12-15T02:41:31Z					biological_process											owl:Class	
GO:0006828	biolink:NamedThing	manganese ion transport	The directed movement of manganese (Mn) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0080029	biolink:NamedThing	cellular response to boron-containing substance levels	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of boron-containing substances.	tmpzr1t_l9r_go_relaxed.owl	cellular response to boron levels													biological_process											owl:Class	
GO:0046627	biolink:NamedThing	negative regulation of insulin receptor signaling pathway	Any process that stops, prevents, or reduces the frequency, rate or extent of insulin receptor signaling.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of insulin receptor signalling pathway|down regulation of insulin receptor signaling pathway|inhibition of insulin receptor signaling pathway|down-regulation of insulin receptor signaling pathway|downregulation of insulin receptor signaling pathway													biological_process											owl:Class	
GO:2000645	biolink:NamedThing	negative regulation of receptor catabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of receptor catabolic process.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of receptor catabolism|negative regulation of receptor degradation|negative regulation of receptor breakdown							vk	2011-04-21T11:20:22Z					biological_process											owl:Class	
GO:0032037	biolink:NamedThing	myosin I heavy chain binding	Binding to a heavy chain of a myosin I complex.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0017024	biolink:NamedThing	myosin I binding	Binding to a class I myosin; myosin I heavy chains are single-headed, possess tails of various lengths, and do not self-associate into bipolar filaments.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0047985	biolink:NamedThing	hydrogen dehydrogenase activity	Catalysis of the reaction: H2 + NAD+ = H+ + NADH.	tmpzr1t_l9r_go_relaxed.owl	H(2):NAD(+) oxidoreductase activity|NAD-linked hydrogenase activity|hydrogenase activity|H2:NAD+ oxidoreductase activity|bidirectional hydrogenase activity|hydrogen:NAD+ oxidoreductase activity				EC:1.12.1.2|RHEA:24636|MetaCyc:HYDROGEN-DEHYDROGENASE-RXN									molecular_function											owl:Class	
GO:0002581	biolink:NamedThing	negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II	Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of antigen (peptide or polysaccharide) via MHC class II.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II|down regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II|inhibition of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II|negative regulation of peptide or polysaccharide antigen processing and presentation via MHC class II|downregulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II													biological_process											owl:Class	
GO:1901980	biolink:NamedThing	positive regulation of inward rectifier potassium channel activity	Any process that activates or increases the frequency, rate or extent of inward rectifier potassium channel activity.	tmpzr1t_l9r_go_relaxed.owl	up regulation of inward rectifier potassium channel activity|up-regulation of Kir channel activity|upregulation of Kir channel activity|up regulation of Kir channel activity|up-regulation of inward rectifier potassium channel activity|activation of inward rectifier potassium channel activity|upregulation of inward rectifier potassium channel activity|activation of Kir channel activity|positive regulation of Kir channel activity							tb	2013-03-12T18:21:17Z					biological_process											owl:Class	
GO:0051222	biolink:NamedThing	positive regulation of protein transport	Any process that activates or increases the frequency, rate or extent of the directed movement of a protein into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	activation of protein transport|stimulation of protein transport|up-regulation of protein transport|up regulation of protein transport|upregulation of protein transport													biological_process											owl:Class	
GO:0072385	biolink:NamedThing	minus-end-directed organelle transport along microtubule	The directed movement of an organelle towards the minus end of a microtubule, mediated by motor proteins. This process begins with the attachment of an organelle to a microtubule, and ends when the organelle reaches its final destination.	tmpzr1t_l9r_go_relaxed.owl	microtubule minus-end-directed organelle distribution|microtubule minus-end-directed organelle localization							mah	2010-12-01T05:01:20Z					biological_process											owl:Class	
GO:0072384	biolink:NamedThing	organelle transport along microtubule	The directed movement of an organelle along a microtubule, mediated by motor proteins. This process begins with the attachment of an organelle to a microtubule, and ends when the organelle reaches its final destination.	tmpzr1t_l9r_go_relaxed.owl	microtubule-based organelle localization							mah	2010-12-01T04:59:11Z					biological_process											owl:Class	
GO:0016090	biolink:NamedThing	prenol metabolic process	The chemical reactions and pathways involving prenols, isoprenoids of general formula (H-CH2-C(CH3)=CH-CH2-)n-OH, any primary monohydroxy alcohol whose carbon skeleton consists of two or more isoprenoid residues linked head to tail.	tmpzr1t_l9r_go_relaxed.owl	prenol metabolism													biological_process											owl:Class	
GO:0036395	biolink:NamedThing	pancreatic amylase secretion	The controlled release of amylase from a cell of the pancreas.	tmpzr1t_l9r_go_relaxed.owl								bf	2013-07-01T13:42:34Z					biological_process											owl:Class	
GO:0036394	biolink:NamedThing	amylase secretion	The controlled release of amylase from a cell.	tmpzr1t_l9r_go_relaxed.owl	amylase release							bf	2013-07-01T13:03:19Z					biological_process											owl:Class	
GO:0034415	biolink:NamedThing	tRNA 3'-trailer cleavage, exonucleolytic	Exonucleolytic cleavage of the 3'-end of the pre-tRNA as part of the process of generating the mature 3'-end of the tRNA.	tmpzr1t_l9r_go_relaxed.owl	tRNA 3'-end cleavage, exonucleolytic|exonucleolytic tRNA 3'-end cleavage|exonucleolytic tRNA 3'-trailer cleavage													biological_process											owl:Class	
GO:0090503	biolink:NamedThing	RNA phosphodiester bond hydrolysis, exonucleolytic	The chemical reactions and pathways involving the hydrolysis of terminal 3',5'-phosphodiester bonds in one or two strands of ribonucleotides.	tmpzr1t_l9r_go_relaxed.owl								tb	2012-10-22T12:05:27Z					biological_process											owl:Class	
GO:0018525	biolink:NamedThing	4-hydroxybenzoyl-CoA reductase activity	Catalysis of the reaction: benzoyl-CoA + oxidized ferredoxin + H2O = 4-hydroxybenzoyl-CoA + reduced ferredoxin.	tmpzr1t_l9r_go_relaxed.owl	4-hydroxybenzoyl-coA:(acceptor) oxidoreductase activity|4-hydroxybenzoyl-coA reductase (dehydroxylating) activity				KEGG_REACTION:R05316|UM-BBD_reactionID:r0158|MetaCyc:OHBENZCOARED-RXN|RHEA:29603|EC:1.1.7.1									molecular_function											owl:Class	
GO:0071840	biolink:NamedThing	cellular component organization or biogenesis	A process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a cellular component.	tmpzr1t_l9r_go_relaxed.owl	cellular component organisation or biogenesis at cellular level|cellular component organisation or biogenesis|cellular component organization or biogenesis at cellular level							mah	2010-09-10T01:39:16Z			GO:0071841		biological_process											owl:Class	
GO:0052875	biolink:NamedThing	riboflavin reductase (NADH) activity	Catalysis of the reaction: reduced riboflavin + NAD+ = riboflavin + NADH + 2 H+.	tmpzr1t_l9r_go_relaxed.owl	NAD(P)H:riboflavin oxidoreductase activity|NAD(P)H-dependent FMN reductase activity|flavin mononucleotide reductase activity|riboflavine mononucleotide reductase activity|flavine mononucleotide reductase activity|NAD(P)H2:FMN oxidoreductase activity|riboflavin mononucleotide reductase activity|NAD(P)H-FMN reductase activity|NAD(P)H:FMN oxidoreductase activity|NAD(P)H2 dehydrogenase (FMN) activity|riboflavin mononucleotide (reduced nicotinamide adenine dinucleotide) reductase activity				MetaCyc:RXN-12445|EC:1.5.1.41|RHEA:31455|KEGG_REACTION:R09750									molecular_function											owl:Class	
GO:0004313	biolink:NamedThing	[acyl-carrier-protein] S-acetyltransferase activity	Catalysis of the reaction: acetyl-CoA + [acyl-carrier protein] = CoA + acetyl-[acyl-carrier protein].	tmpzr1t_l9r_go_relaxed.owl	ACP S-acetyltransferase activity|acetyl-CoA:acyl-carrier-protein S-acetyltransferase activity|acyl-carrier-protein S-acetyltransferase activity|ACPacetyltransferase activity|[acyl-carrier protein] S-acetyltransferase activity|ACP acetyltransferase activity|ACAT activity|acyl-carrier-proteinacetyltransferase activity|acyl-carrier-protein acetyltransferase activity|acetyl coenzyme A-acyl-carrier-protein transacylase activity				MetaCyc:ACP-S-ACETYLTRANSFER-RXN|RHEA:41788|EC:2.3.1.38									molecular_function											owl:Class	
GO:0048016	biolink:NamedThing	inositol phosphate-mediated signaling	Any intracellular signal transduction in which the signal is passed on within the cell via an inositol phosphate. Includes production of the inositol phosphate, and downstream effectors that further transmit the signal within the cell. Inositol phosphates are a group of mono- to poly-phosphorylated inositols, and include inositol monophosphate (IP), inositol trisphosphate (IP3), inositol pentakisphosphate (IP5) and inositol hexaphosphate (IP6).	tmpzr1t_l9r_go_relaxed.owl	inositol phosphate-mediated signalling													biological_process											owl:Class	
GO:0019932	biolink:NamedThing	second-messenger-mediated signaling	Any intracellular signal transduction in which the signal is passed on within the cell via a second messenger; a small molecule or ion that can be quickly generated or released from intracellular stores, and can diffuse within the cell. Second-messenger signaling includes production or release of the second messenger, and effectors downstream of the second messenger that further transmit the signal within the cell.	tmpzr1t_l9r_go_relaxed.owl	second messenger-mediated signaling|second messenger-mediated signalling|second-messenger-mediated signal transduction|second messenger mediated signaling|second-messenger-mediated signalling|second messenger mediated signalling													biological_process											owl:Class	
GO:1900136	biolink:NamedThing	regulation of chemokine activity	Any process that modulates the frequency, rate or extent of chemokine activity.	tmpzr1t_l9r_go_relaxed.owl								bf	2012-02-28T01:36:29Z					biological_process											owl:Class	
GO:1902564	biolink:NamedThing	negative regulation of neutrophil activation	Any process that stops, prevents or reduces the frequency, rate or extent of neutrophil activation.	tmpzr1t_l9r_go_relaxed.owl	downregulation of neutrophil activation|inhibition of neutrophil activation|down-regulation of neutrophil activation|down regulation of neutrophil activation							ecu	2013-12-10T15:33:16Z					biological_process											owl:Class	
GO:0051206	biolink:NamedThing	silicate metabolic process	The chemical reactions and pathways involving silicates, the salts of silicic acids. Silicates are usually composed of silicon and oxygen (Si[x]O[y]), one or more metals, and possibly hydrogen. Types of silicate include unisilicates, metasilicates and hydrous silicates.	tmpzr1t_l9r_go_relaxed.owl	silicate metabolism													biological_process											owl:Class	
GO:0043436	biolink:NamedThing	oxoacid metabolic process	The chemical reactions and pathways involving any oxoacid; an oxoacid is a compound which contains oxygen, at least one other element, and at least one hydrogen bound to oxygen, and which produces a conjugate base by loss of positive hydrogen ion(s) (hydrons).	tmpzr1t_l9r_go_relaxed.owl	oxo acid metabolism|keto acid metabolic process|ketoacid metabolic process|keto acid metabolism|oxo acid metabolic process|oxoacid metabolism|ketoacid metabolism													biological_process											owl:Class	
GO:0102647	biolink:NamedThing	D-ribose 5-phosphate:D-sedoheptulose 7-phosphate transaldolase activity	Catalysis of the reaction: sedoheptulose 7-phosphate + D-ribose 5-phosphate <=> D-glycero-D-altro-octulose 8-phosphate + D-erythrose 4-phosphate.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-15789									molecular_function											owl:Class	
GO:0019931	biolink:NamedThing	protein-chromophore linkage via peptidyl-N6-3-dehydroretinal-L-lysine	The modification of peptidyl-lysine to form N6-3,4-didehydroretinylidene-L-lysine.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0312									biological_process											owl:Class	
GO:0062148	biolink:NamedThing	L-gamma-glutamyl-L-propargylglycine hydroxylase activity	Catalysis of the reaction: 2-oxoglutarate + L-gamma-glutamyl-L-propargylglycine + O2 = CO2 + L-gamma-glutamyl-(3R)-L-beta-ethynylserine + succinate.	tmpzr1t_l9r_go_relaxed.owl					RHEA:59900			dph	2019-09-02T17:04:43Z					molecular_function											owl:Class	
GO:1904403	biolink:NamedThing	cellular response to nocodazole	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nocodazole stimulus.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-06-23T21:10:52Z					biological_process											owl:Class	
GO:0044277	biolink:NamedThing	cell wall disassembly	A process that results in the breakdown of the cell wall.	tmpzr1t_l9r_go_relaxed.owl	cellular cell wall disassembly							jl	2010-01-14T02:00:34Z			GO:0060871		biological_process											owl:Class	
GO:0090688	biolink:NamedThing	cleavage furrow rim	The part of the cleavage furrow closest to the cell surface.	tmpzr1t_l9r_go_relaxed.owl								tb	2016-07-26T16:00:10Z					cellular_component											owl:Class	
GO:0070099	biolink:NamedThing	regulation of chemokine-mediated signaling pathway	Any process that modulates the rate, frequency or extent of the series of molecular events generated as a consequence of a chemokine binding to a cell surface receptor.	tmpzr1t_l9r_go_relaxed.owl	regulation of chemokine-mediated signalling pathway													biological_process											owl:Class	
GO:1900976	biolink:NamedThing	positive regulation of tatiopterin biosynthetic process	Any process that activates or increases the frequency, rate or extent of tatiopterin biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	activation of tatiopterin anabolism|positive regulation of tatiopterin synthesis|upregulation of tatiopterin biosynthesis|up regulation of tatiopterin anabolism|upregulation of tatiopterin synthesis|activation of tatiopterin synthesis|up-regulation of tatiopterin synthesis|up-regulation of tatiopterin biosynthetic process|up regulation of tatiopterin formation|upregulation of tatiopterin formation|up-regulation of tatiopterin biosynthesis|activation of tatiopterin biosynthesis|positive regulation of tatiopterin formation|up regulation of tatiopterin biosynthesis|activation of tatiopterin biosynthetic process|upregulation of tatiopterin biosynthetic process|up regulation of tatiopterin biosynthetic process|upregulation of tatiopterin anabolism|up-regulation of tatiopterin formation|up-regulation of tatiopterin anabolism|positive regulation of tatiopterin anabolism|positive regulation of tatiopterin biosynthesis|activation of tatiopterin formation|up regulation of tatiopterin synthesis							tt	2012-06-14T04:02:14Z					biological_process											owl:Class	
GO:0033597	biolink:NamedThing	mitotic checkpoint complex	A multiprotein complex that functions as a mitotic checkpoint inhibitor of the anaphase-promoting complex/cyclosome (APC/C). In budding yeast this complex consists of Mad2p, Mad3p, Bub3p and Cdc20p, and in mammalian cells it consists of MAD2, BUBR1, BUB3, and CDC20.	tmpzr1t_l9r_go_relaxed.owl	MCC													cellular_component											owl:Class	
GO:0034890	biolink:NamedThing	endosulfan diol hydrolyase (cyclizing) activity	Catalysis of the reaction: endosulfan diol = endosulfan ether + H2O.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r1386									molecular_function											owl:Class	
GO:0006225	biolink:NamedThing	UDP biosynthetic process	The chemical reactions and pathways resulting in the formation of UDP, uridine (5'-)diphosphate.	tmpzr1t_l9r_go_relaxed.owl	UDP synthesis|UDP biosynthesis|UDP anabolism|UDP formation													biological_process											owl:Class	
GO:0004564	biolink:NamedThing	beta-fructofuranosidase activity	Catalysis of the reaction: a fructofuranosylated fructofuranosyl acceptor + H2O = a non fructofuranosylated fructofuranosyl acceptor + a beta-D-fructofuranoside.	tmpzr1t_l9r_go_relaxed.owl	invertase activity|maxinvert L 1000 activity|invertin activity|saccharase activity|alkaline invertase activity|fructosylinvertase activity|acid invertase activity|beta-h-fructosidase activity|glucosucrase activity|beta-fructosidase activity|beta-D-fructofuranoside fructohydrolase activity				MetaCyc:RXN-9985|EC:3.2.1.26									molecular_function											owl:Class	
GO:0034148	biolink:NamedThing	negative regulation of toll-like receptor 5 signaling pathway	Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 5 signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of TLR5 signaling pathway|negative regulation of toll-like receptor 5 signalling pathway													biological_process											owl:Class	
GO:0034147	biolink:NamedThing	regulation of toll-like receptor 5 signaling pathway	Any process that modulates the frequency, rate, or extent of toll-like receptor 5 signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	regulation of toll-like receptor 5 signalling pathway|regulation of TLR5 signaling pathway													biological_process											owl:Class	
GO:0097098	biolink:NamedThing	DNA/RNA hybrid annealing activity	An activity that facilitates the base-pairing of single-stranded RNA to double-stranded DNA resulting in the formation of R-loops.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/2161						pr	2011-07-07T11:20:44Z					molecular_function											owl:Class	
GO:1900743	biolink:NamedThing	positive regulation of filamentous growth of a population of unicellular organisms in response to pH	Any process that activates or increases the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to pH.	tmpzr1t_l9r_go_relaxed.owl	upregulation of filamentous growth of a population of unicellular organisms in response to pH|activation of filamentous growth of a population of unicellular organisms in response to pH|up-regulation of filamentous growth of a population of unicellular organisms in response to pH|up regulation of filamentous growth of a population of unicellular organisms in response to pH							di	2012-05-28T02:35:11Z					biological_process											owl:Class	
GO:1900430	biolink:NamedThing	positive regulation of filamentous growth of a population of unicellular organisms	Any process that activates or increases the frequency, rate or extent of filamentous growth of a population of unicellular organisms.	tmpzr1t_l9r_go_relaxed.owl	activation of filamentous growth of a population of unicellular organisms|up regulation of filamentous growth of a population of unicellular organisms|upregulation of filamentous growth of a population of unicellular organisms|up-regulation of filamentous growth of a population of unicellular organisms							di	2012-04-25T05:53:52Z					biological_process											owl:Class	
GO:0002361	biolink:NamedThing	CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation	The process in which a precursor cell type acquires the specialized features of a CD4-positive, CD25-positive, alpha-beta regulatory T cell.	tmpzr1t_l9r_go_relaxed.owl	CD4-positive, CD25-positive, alpha-beta regulatory T-lymphocyte differentiation|CD4-positive, CD25-positive, alpha-beta regulatory T cell development|CD4-positive, CD25-positive, alpha-beta regulatory T lymphocyte differentiation|CD4-positive, CD25-positive, alpha-beta regulatory T-cell differentiation					Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.								biological_process											owl:Class	
GO:0043367	biolink:NamedThing	CD4-positive, alpha-beta T cell differentiation	The process in which a relatively unspecialized T cell acquires specialized features of a mature CD4-positive, alpha-beta T cell.	tmpzr1t_l9r_go_relaxed.owl	CD4-positive, alpha-beta T-lymphocyte differentiation|CD4-positive, alpha beta T cell development|CD4-positive, alpha-beta T-cell differentiation|CD4-positive, alpha beta T cell differentiation|CD4-positive, alpha-beta T lymphocyte differentiation					Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.								biological_process											owl:Class	
GO:2000709	biolink:NamedThing	regulation of maintenance of meiotic sister chromatid cohesion, centromeric	Any process that modulates the frequency, rate or extent of maintenance of meiotic sister chromatid cohesion in the centromeric region.	tmpzr1t_l9r_go_relaxed.owl	regulation of maintenance of sister chromatin cohesion at centromere at meiosis I|regulation of maintenance of centromeric meiotic sister chromatin cohesion|regulation of maintenance of meiotic sister chromatin cohesion at centromere							mah	2011-06-01T12:41:11Z					biological_process											owl:Class	
GO:0070602	biolink:NamedThing	regulation of centromeric sister chromatid cohesion	Any process that modulates the frequency, rate or extent of sister chromatid cohesion in the centromeric region of a chromosome.	tmpzr1t_l9r_go_relaxed.owl	regulation of sister chromatid cohesion at centromere							mah	2009-04-28T04:32:53Z					biological_process											owl:Class	
GO:0009022	biolink:NamedThing	tRNA nucleotidyltransferase activity	Catalysis of the reaction: tRNA(n+1) + phosphate = tRNA(n) + a nucleoside diphosphate.	tmpzr1t_l9r_go_relaxed.owl	RNase PH activity|tRNA:phosphate nucleotidyltransferase activity|ribonuclease PH activity|phosphate-dependent exonuclease activity				EC:2.7.7.56|MetaCyc:TRNA-NUCLEOTIDYLTRANSFERASE-RXN|RHEA:10628	Note that, although the enzyme to which this term refers is also known as 'ribonuclease PH', and degrades tRNA in the 3'-5' direction in vivo, the term does not have parentage in the 'nuclease activity' branch of the ontology because both GO and the Enzyme Commission define nuclease activity as a type of hydrolysis.								molecular_function											owl:Class	
GO:0007060	biolink:NamedThing	male meiosis chromosome segregation	The cell cycle process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets during the meiotic cell cycle in a male.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:2001158	biolink:NamedThing	positive regulation of proline catabolic process to glutamate	Any process that activates or increases the frequency, rate or extent of proline catabolic process to glutamate.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of proline degradation to glutamate|positive regulation of proline breakdown to glutamate|positive regulation of proline oxidation							mcc	2011-10-25T08:54:50Z					biological_process											owl:Class	
GO:0033243	biolink:NamedThing	positive regulation of cellular amine catabolic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of amines.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of amine breakdown|positive regulation of amine degradation|positive regulation of amine catabolism													biological_process											owl:Class	
GO:2000848	biolink:NamedThing	positive regulation of corticosteroid hormone secretion	Any process that activates or increases the frequency, rate or extent of corticosteroid hormone secretion.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of corticosteroid secretion							bf	2011-07-26T08:43:45Z					biological_process											owl:Class	
GO:0032990	biolink:NamedThing	cell part morphogenesis	The process in which the anatomical structures of a cell part are generated and organized.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0032989	biolink:NamedThing	cellular component morphogenesis	The process in which cellular structures, including whole cells or cell parts, are generated and organized.	tmpzr1t_l9r_go_relaxed.owl	cellular structure morphogenesis													biological_process											owl:Class	
GO:0007093	biolink:NamedThing	mitotic cell cycle checkpoint signaling	A signaling process that ensures accurate chromosome replication and segregation by preventing progression through a mitotic cell cycle until conditions are suitable for the cell to proceed to the next stage.	tmpzr1t_l9r_go_relaxed.owl	signal transduction involved in mitotic cell cycle checkpoint|mitotic checkpoint|signal transduction involved in mitotic G2/M transition checkpoint|signal transduction involved in mitotic cell cycle G1/S checkpoint|mitotic cell cycle checkpoint	https://github.com/geneontology/go-ontology/issues/20935										GO:0072474|GO:0072456|GO:0031575|GO:0071780|GO:0072413		biological_process											owl:Class	
GO:0019590	biolink:NamedThing	L-arabitol catabolic process to xylulose 5-phosphate	The chemical reactions and pathways resulting in the breakdown of L-arabitol to form xylulose 5-phosphate. L-arabitol is converted into L-xylulose, which is then phosphorylated to L-xylulose-5-phosphate. This is converted to D-xylulose-5-phosphate via the intermediate L-ribulose-5-phosphate.	tmpzr1t_l9r_go_relaxed.owl	L-arabitol degradation to xylulose 5-phosphate|L-arabitol utilization|L-arabitol and xylitol degradation|L-arabitol breakdown to xylulose 5-phosphate				MetaCyc:LARABITOLUTIL-PWY									biological_process											owl:Class	
GO:1905595	biolink:NamedThing	regulation of low-density lipoprotein particle receptor binding	Any process that modulates the frequency, rate or extent of low-density lipoprotein particle receptor binding.	tmpzr1t_l9r_go_relaxed.owl	regulation of low-density lipoprotein receptor binding|regulation of LDL receptor binding							nc	2016-10-26T10:57:23Z					biological_process											owl:Class	
GO:0047029	biolink:NamedThing	(R)-4-hydroxyphenyllactate dehydrogenase (NADPH) activity	Catalysis of the reaction: NADP+ + (R)-3-(4-hydroxyphenyl)lactate = NADPH + H+ + 3-(4-hydroxyphenyl)pyruvate.	tmpzr1t_l9r_go_relaxed.owl	hydroxyphenylpyruvate reductase activity|aromatic 2-oxoacid reductase activity|phenylpyruvate reductase activity				https://github.com/geneontology/go-ontology/issues/21412|RHEA:52692|MetaCyc:RXN-7632									molecular_function											owl:Class	
GO:0035818	biolink:NamedThing	positive regulation of urine volume by pressure natriuresis	An increase in the amount of urine excreted over a unit of time, as a result of pressure natriuresis.	tmpzr1t_l9r_go_relaxed.owl	diuresis resulting from pressure natriuresis							bf	2011-04-20T01:55:42Z					biological_process											owl:Class	
GO:0035810	biolink:NamedThing	positive regulation of urine volume	Any process that increases the amount of urine excreted from the body over a unit of time.	tmpzr1t_l9r_go_relaxed.owl	elevation of urinary volume|diuresis|increase in urine flow							bf	2011-04-20T01:19:38Z					biological_process											owl:Class	
GO:0106041	biolink:NamedThing	positive regulation of GABA-A receptor activity	Any process that activates or increases the frequency, rate or extent of GABA-A receptor activity.	tmpzr1t_l9r_go_relaxed.owl								hjd	2017-07-27T18:51:30Z					biological_process											owl:Class	
GO:0106040	biolink:NamedThing	regulation of GABA-A receptor activity	Any process that modulates the frequency, rate or extent of GABA-A receptor activity.	tmpzr1t_l9r_go_relaxed.owl								hjd	2017-07-27T18:47:02Z					biological_process											owl:Class	
GO:0060004	biolink:NamedThing	reflex	An automatic response to a stimulus beginning with a nerve impulse from a receptor and ending with the action of an effector such as a gland or a muscle. Signaling never reaches a level of consciousness.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Reflex									biological_process											owl:Class	
GO:0042825	biolink:NamedThing	TAP complex	A heterodimer composed of the subunits TAP1 and TAP2 (transporter associated with antigen presentation). Functions in the transport of antigenic peptides from the cytosol to the lumen of the endoplasmic reticulum.	tmpzr1t_l9r_go_relaxed.owl	transporter associated with antigen presentation													cellular_component											owl:Class	
GO:0010524	biolink:NamedThing	positive regulation of calcium ion transport into cytosol	Any process that increases the rate of the directed movement of calcium ions into the cytosol of a cell. The cytosol is that part of the cytoplasm that does not contain membranous or particulate subcellular components.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0009372	biolink:NamedThing	quorum sensing	The cell-cell signaling process in which single-celled organisms carry out coordinated responses by monitoring their own population density, and often also that of other microbes, by producing small, diffusible, signal molecules, detecting the concentration of these molecules, and triggering a signal transduction pathway when a certain threshold is reached. Quorum sensing can occur amongst microbial communities in the environment or within host organisms.	tmpzr1t_l9r_go_relaxed.owl	quorum sensing system|detection of cell density by secreted molecule|cell-cell signaling involved in quorum sensing				Wikipedia:Quorum_sensing							GO:0060247|GO:0010699		biological_process											owl:Class	
GO:0060245	biolink:NamedThing	detection of cell density	The series of events in which information about the density of cells in a population is received and converted into a molecular signal.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1903897	biolink:NamedThing	regulation of PERK-mediated unfolded protein response	Any process that modulates the frequency, rate or extent of the PERK-mediated unfolded protein response.	tmpzr1t_l9r_go_relaxed.owl	regulation of endoplasmic reticulum unfolded protein response; PERK signaling|regulation of UPR signaling by PERK stress sensor|regulation of PERK branch of UPR|regulation of PERK signaling in response to endoplasmic reticulum stress|regulation of PERK signal transduction pathway|regulation of PKR-like ER kinase signal transduction|regulation of EIF2AK3-mediated unfolded protein response							bf	2015-02-09T10:18:14Z					biological_process											owl:Class	
GO:0009373	biolink:NamedThing	regulation of transcription by pheromones	Any process involving pheromones that modulates the frequency, rate or extent of transcription.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1903569	biolink:NamedThing	positive regulation of protein localization to ciliary membrane	Any process that activates or increases the frequency, rate or extent of protein localization to ciliary membrane.	tmpzr1t_l9r_go_relaxed.owl	upregulation of protein localisation in ciliary membrane|positive regulation of protein localisation in ciliary membrane|up regulation of protein localization to ciliary membrane|activation of protein localization in ciliary membrane|positive regulation of protein localisation to ciliary membrane|up regulation of protein localisation to ciliary membrane|up regulation of protein localization in ciliary membrane|upregulation of protein localisation to ciliary membrane|up-regulation of protein localisation to ciliary membrane|up-regulation of protein localisation in ciliary membrane|up-regulation of protein localization to ciliary membrane|up regulation of protein localisation in ciliary membrane|upregulation of protein localization in ciliary membrane|activation of protein localisation in ciliary membrane|activation of protein localization to ciliary membrane|positive regulation of protein localization in ciliary membrane|upregulation of protein localization to ciliary membrane|up-regulation of protein localization in ciliary membrane|activation of protein localisation to ciliary membrane							krc	2014-10-24T21:33:08Z					biological_process											owl:Class	
GO:1904377	biolink:NamedThing	positive regulation of protein localization to cell periphery	Any process that activates or increases the frequency, rate or extent of protein localization to cell periphery.	tmpzr1t_l9r_go_relaxed.owl	activation of protein localization to cell periphery|up-regulation of protein localization to cell periphery|upregulation of protein localization to cell periphery|up regulation of protein localization to cell periphery							sl	2015-06-22T22:09:37Z					biological_process											owl:Class	
GO:0002546	biolink:NamedThing	negative regulation of tissue kallikrein-kinin cascade	Any process that stops, prevents, or reduces the frequency, rate, or extent of the tissue kallikrein-kinin cascade.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of tissue kallikrein-kinin cascade|inhibition of tissue kallikrein-kinin cascade|downregulation of tissue kallikrein-kinin cascade|negative regulation of glandular kallikrein-kinin cascade|down regulation of tissue kallikrein-kinin cascade													biological_process											owl:Class	
GO:0002382	biolink:NamedThing	regulation of tissue kallikrein-kinin cascade	Any process that modulates the frequency, rate, or extent of the tissue kallikrein-kinin cascade.	tmpzr1t_l9r_go_relaxed.owl	regulation of glandular kallikrein-kinin cascade													biological_process											owl:Class	
GO:0015965	biolink:NamedThing	diadenosine tetraphosphate metabolic process	The chemical reactions and pathways involving diadenosine tetraphosphate, a derivative of the nucleoside adenosine with four phosphate groups attached.	tmpzr1t_l9r_go_relaxed.owl	diadenosine tetraphosphate metabolism													biological_process											owl:Class	
GO:0015959	biolink:NamedThing	diadenosine polyphosphate metabolic process	The chemical reactions and pathways involving diadenosine polyphosphate, a derivative of the nucleoside adenosine with phosphate groups attached.	tmpzr1t_l9r_go_relaxed.owl	diadenosine polyphosphate metabolism													biological_process											owl:Class	
GO:0098728	biolink:NamedThing	germline stem cell asymmetric division	The self-renewing division of a germline stem cell, to produce a daughter stem cell and a daughter germ cell which will divide to form one or more gametes.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0140032	biolink:NamedThing	glycosylation-dependent protein binding	Binding to a protein upon glycosylation of the target protein.	tmpzr1t_l9r_go_relaxed.owl						This term should only be used when the binding is shown to require glycosylation of the target protein: the interaction needs to be tested with and without the PTM. The binding does not need to be at the site of glycosylation. It may be that the glycosylation causes a conformational change that allows binding of the protein to another region; this type of glycosylation-dependent protein binding is valid for annotation to this term.		pg	2017-05-17T15:20:50Z					molecular_function											owl:Class	
GO:0038146	biolink:NamedThing	chemokine (C-X-C motif) ligand 12 signaling pathway	A series of molecular signals initiated by the binding of the chemokine CXCL12 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.	tmpzr1t_l9r_go_relaxed.owl	CXCL12 signaling pathway|stromal cell-derived factor-1 signaling pathway|CXCL12-activated CXCR7 signaling pathway|SDF1 signaling pathway							bf	2012-05-11T11:26:17Z					biological_process											owl:Class	
GO:1902098	biolink:NamedThing	calcitriol binding	Binding to calcitriol. Calcitriol (1,25-dihydroxycholecalciferol) is the hormonally active form of vitamin D3.	tmpzr1t_l9r_go_relaxed.owl	1,25-dihydroxyvitamin D3 binding|hormonally active vitamin D3 binding|1alpha,25-dihydroxyvitamin D3 binding|1alpha,25-dihydroxycholecalciferol binding|1alpha,25(OH)2D3 binding|1alpha,25(OH)2 vitamin D3 binding|1,25-dihydroxycholecalciferol binding							bf	2013-05-02T09:41:15Z					molecular_function											owl:Class	
GO:1902271	biolink:NamedThing	D3 vitamins binding	Binding to D3 vitamins.	tmpzr1t_l9r_go_relaxed.owl								bf	2013-07-01T12:54:37Z					molecular_function											owl:Class	
GO:0110078	biolink:NamedThing	TTT complex	A protein complex responsible for the stabilisation of protein levels of the phosphatidylinositol 3-kinase-related protein kinase (PIKK) family proteins. The TTT complex can also be found as part of the ASTRA complex (GO:0070209).	tmpzr1t_l9r_go_relaxed.owl	Triple T complex|TELO2-TTI1-TTI2|Tel2-Tti1-Tti2							kmv	2018-01-29T21:39:52Z					cellular_component											owl:Class	
GO:0002423	biolink:NamedThing	natural killer cell mediated immune response to tumor cell	An immune response mediated by a natural killer cell triggered in response to the presence of a tumor cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0002418	biolink:NamedThing	immune response to tumor cell	An immune system process that functions in the response of an organism to a tumor cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0048713	biolink:NamedThing	regulation of oligodendrocyte differentiation	Any process that modulates the frequency, rate or extent of oligodendrocyte differentiation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0070902	biolink:NamedThing	mitochondrial tRNA pseudouridine synthesis	The intramolecular conversion of uridine to pseudouridine in a mitochondrial tRNA molecule.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-09-02T04:09:48Z					biological_process											owl:Class	
GO:0140233	biolink:NamedThing	intracellular cAMP-activated cation channel activity involved in regulation of postsynaptic membrane potential	Enables the transmembrane transfer of a cation by a channel that opens when intracellular cAMP has been bound by the channel complex or one of its constituent parts, to regulate the postsynaptic membrane potential.	tmpzr1t_l9r_go_relaxed.owl	intracellular cAMP activated cation channel activity involved in regulation of postsynaptic membrane potential	https://github.com/geneontology/synapse/issues/231				Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.		pg	2018-07-09T11:31:18Z					molecular_function											owl:Class	
GO:0071251	biolink:NamedThing	cellular response to silicon dioxide	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a silicon dioxide stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to silica|cellular response to silox							mah	2009-12-03T03:09:41Z					biological_process											owl:Class	
GO:0072292	biolink:NamedThing	epithelial cell migration involved in metanephric proximal tubule morphogenesis	The orderly movement of epithelial cells within a renal tubule that contributes to metanephric proximal tubule morphogenesis.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-04-09T03:54:28Z					biological_process											owl:Class	
GO:0050234	biolink:NamedThing	pyrazolylalanine synthase activity	Catalysis of the reaction: L-serine + pyrazole = 3-(pyrazol-1-yl)-L-alanine + H(2)O.	tmpzr1t_l9r_go_relaxed.owl	L-serine hydro-lyase [adding pyrazole; 3-(pyrazol-1-yl)-L-alanine-forming]|beta-pyrazolylalaninase activity|L-serine hydro-lyase (adding pyrazole)				KEGG_REACTION:R02378|MetaCyc:PYRAZOLYLALANINE-SYNTHASE-RXN|EC:4.2.1.50|RHEA:24512									molecular_function											owl:Class	
GO:0003337	biolink:NamedThing	mesenchymal to epithelial transition involved in metanephros morphogenesis	A transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the metanephros.	tmpzr1t_l9r_go_relaxed.owl	metanephric mesenchyme to epithelial transition							dph	2009-11-24T09:29:49Z					biological_process											owl:Class	
GO:0070510	biolink:NamedThing	regulation of histone H4-K20 methylation	Any process that modulates the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 20 of histone H4.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0031060	biolink:NamedThing	regulation of histone methylation	Any process that modulates the frequency, rate or extent of the covalent addition of methyl groups to histones.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0015127	biolink:NamedThing	bilirubin transmembrane transporter activity	Enables the transfer of bilirubin from one side of a membrane to the other. Bilirubin is a linear tetrapyrrole produced in the reticuloendothelial system from biliverdin and transported to the liver as a complex with serum albumin. In the liver, bilirubin is converted to bilirubin bisglucuronide, which is excreted in the bile.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-9661417|Reactome:R-HSA-5679031|Reactome:R-HSA-5679041									molecular_function											owl:Class	
GO:0021805	biolink:NamedThing	cell movement involved in somal translocation	The movement of a cell body from the ventricular zone to the pial surface with a concomitant shortening of the process that extends to the pial surface.	tmpzr1t_l9r_go_relaxed.owl	cell motility involved in somal translocation													biological_process											owl:Class	
GO:0008275	biolink:NamedThing	gamma-tubulin small complex	A complex usually comprising two gamma-tubulin molecules and two conserved non-tubulin proteins. Some gamma-tubulin small complexes are thought to be the repeating unit making up the core of the gamma-tubulin ring complex.	tmpzr1t_l9r_go_relaxed.owl	gammaTuSC|gamma-tubulin small complex, centrosomal|gamma-tubulin small complex, spindle pole body|gamma-tubulin small complex, mitotic spindle pole body|Tub4 complex	https://github.com/geneontology/go-ontology/issues/20967										GO:0000928|GO:0000927|GO:0061495		cellular_component											owl:Class	
GO:0070794	biolink:NamedThing	negative regulation of conidiophore development	Any process that stops, prevents, or reduces the frequency, rate or extent of conidiophore development, a process that leads to the formation of a conidiophore. The conidiophore is a specialized hypha that extends aerially from the growth substrate and bears conidia, or asexual spores.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-07-08T03:06:48Z					biological_process											owl:Class	
GO:0003056	biolink:NamedThing	regulation of vascular associated smooth muscle contraction	Any process that increases the frequency, rate or extent of vascular smooth muscle contraction.	tmpzr1t_l9r_go_relaxed.owl	regulation of vascular smooth muscle contraction													biological_process											owl:Class	
GO:0045701	biolink:NamedThing	negative regulation of spermatid nuclear differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of spermatid nuclear differentiation.	tmpzr1t_l9r_go_relaxed.owl	downregulation of spermatid nuclear differentiation|inhibition of spermatid nuclear differentiation|down regulation of spermatid nuclear differentiation|down-regulation of spermatid nuclear differentiation													biological_process											owl:Class	
GO:0008055	biolink:NamedThing	ocellus pigment biosynthetic process	The chemical reactions and pathways resulting in the formation of ocellus pigments,  general or particular coloring matter in living organisms, found or utilized in the ocellus, a minute simple eye found in many invertebrates.	tmpzr1t_l9r_go_relaxed.owl	ocellus pigment synthesis|ocellus pigment anabolism|ocellus pigment biosynthesis|ocellus pigment formation													biological_process											owl:Class	
GO:0061060	biolink:NamedThing	negative regulation of peptidoglycan recognition protein signaling pathway	Any process that decreases the rate, frequency, or extent of the peptidoglycan recognition protein signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of peptidoglycan recognition protein signalling pathway							dph	2010-03-02T12:38:42Z					biological_process											owl:Class	
GO:0035442	biolink:NamedThing	dipeptide transmembrane transport	The directed movement of a dipeptide across a membrane by means of some agent such as a transporter or pore. A dipeptide is a combination of two amino acids linked together by a peptide (-CO-NH-) bond.	tmpzr1t_l9r_go_relaxed.owl	dipeptide membrane transport					Note that this term is not intended for use in annotating lateral movement within membranes.		bf	2010-04-13T09:18:33Z					biological_process											owl:Class	
GO:0035672	biolink:NamedThing	oligopeptide transmembrane transport	The process in which an oligopeptide is transported across a membrane. Oligopeptides are molecules that contain a small number (2 to 20) of amino-acid residues connected by peptide linkages.	tmpzr1t_l9r_go_relaxed.owl	oligopeptide membrane transport					Note that this term is not intended for use in annotating lateral movement within membranes.		bf	2011-02-08T02:18:07Z					biological_process											owl:Class	
GO:0051468	biolink:NamedThing	detection of glucocorticoid hormone stimulus	The series of events by which a glucocorticoid hormone stimulus is received by a cell and converted into a molecular signal. Glucocorticoids are hormonal C21 corticosteroids synthesized from cholesterol with the ability to bind with the cortisol receptor and trigger similar effects. Glucocorticoids act primarily on carbohydrate and protein metabolism, and have anti-inflammatory effects.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0051467	biolink:NamedThing	detection of steroid hormone stimulus	The series of events by which a steroid hormone stimulus is received by a cell and converted into a molecular signal.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0007198	biolink:NamedThing	adenylate cyclase-inhibiting serotonin receptor signaling pathway	The series of molecular signals generated as a consequence of a serotonin receptor binding to its physiological ligand, where the pathway proceeds with inhibition of adenylyl cyclase and a subsequent decrease in the concentration of cyclic AMP (cAMP).	tmpzr1t_l9r_go_relaxed.owl	serotonin receptor, adenylyl cyclase inhibiting pathway|inhibition of adenylate cyclase activity by serotonin receptor signalling pathway|serotonin receptor, adenylate cyclase inhibiting pathway|inhibition of adenylate cyclase activity by serotonin receptor signaling pathway													biological_process											owl:Class	
GO:0098664	biolink:NamedThing	G protein-coupled serotonin receptor signaling pathway	The series of molecular signals generated as a consequence of a G protein-coupled serotonin receptor binding to one of its physiological ligands.	tmpzr1t_l9r_go_relaxed.owl	G-protein coupled serotonin receptor signaling pathway							dos	2016-12-21T12:07:58Z					biological_process											owl:Class	
GO:0016422	biolink:NamedThing	mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + m(7)G(5')pppAm = S-adenosyl-L-homocysteine + m(7)G(5')pppm(6)Am.	tmpzr1t_l9r_go_relaxed.owl	S-adenosyl-L-methionine:mRNA (2'-O-methyladenosine-6-N-)-methyltransferase activity|S-adenosyl-L-methionine:mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity|messenger ribonucleate 2'-O-methyladenosine NG-methyltransferase activity				EC:2.1.1.62|RHEA:22744|MetaCyc:2.1.1.62-RXN									molecular_function											owl:Class	
GO:0033516	biolink:NamedThing	L-methionine biosynthetic process from homoserine via O-phospho-L-homoserine and cystathionine	The chemical reactions and pathways resulting in the formation of L-methionine from other compounds, including homoserine, via the intermediates O-phospho-L-homoserine and cystathionine.	tmpzr1t_l9r_go_relaxed.owl	methionine biosynthetic process from homoserine via O-phospho-L-homoserine and cystathionine|L-methionine synthesis from homoserine via O-phospho-L-homoserine and cystathionine|L-methionine formation from homoserine via O-phospho-L-homoserine and cystathionine|L-methionine anabolism from homoserine via O-phospho-L-homoserine and cystathionine				MetaCyc:PWY-702									biological_process											owl:Class	
GO:0019279	biolink:NamedThing	L-methionine biosynthetic process from L-homoserine via cystathionine	The chemical reactions and pathways resulting in the formation of L-methionine from other compounds, including L-homoserine, via the intermediate cystathionine.	tmpzr1t_l9r_go_relaxed.owl	methionine biosynthetic process from L-homoserine via cystathionine|L-methionine formation from L-homoserine via cystathionine|L-methionine synthesis from L-homoserine via cystathionine|L-methionine anabolism from L-homoserine via cystathionine				MetaCyc:HOMOSER-METSYN-PWY									biological_process											owl:Class	
GO:0008674	biolink:NamedThing	2-dehydro-3-deoxy-6-phosphogalactonate aldolase activity	Catalysis of the reaction: 6-phospho-2-dehydro-3-deoxy-D-galactonate = D-glyceraldehyde 3-phosphate + pyruvate.	tmpzr1t_l9r_go_relaxed.owl	2-keto-3-deoxy-6-phosphogalactonic aldolase activity|6-phospho-2-dehydro-3-deoxygalactonate aldolase activity|2-dehydro-3-deoxyphosphogalactonate aldolase activity|phospho-2-keto-3-deoxygalactonic aldolase activity|2-keto-3-deoxy-6-phosphogalactonic acid aldolase activity|phospho-2-keto-3-deoxygalactonate aldolase activity|2-oxo-3-deoxygalactonate 6-phosphate aldolase activity|(KDPGal)aldolase activity|2-dehydro-3-deoxy-D-galactonate-6-phosphate D-glyceraldehyde-3-phosphate-lyase activity|6-phospho-2-keto-3-deoxygalactonate aldolase activity|2-dehydro-3-deoxy-D-galactonate-6-phosphate D-glyceraldehyde-3-phosphate-lyase (pyruvate-forming)				RHEA:24464|KEGG_REACTION:R01064|MetaCyc:DEHYDDEOXPHOSGALACT-ALDOL-RXN|EC:4.1.2.21									molecular_function											owl:Class	
GO:1900218	biolink:NamedThing	negative regulation of apoptotic process involved in metanephric nephron tubule development	Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic process involved in metanephric nephron tubule development.	tmpzr1t_l9r_go_relaxed.owl	downregulation of apoptotic programmed cell death of metanephric nephron tubule development|inhibition of apoptotic programmed cell death of metanephric nephron tubule development|downregulation of programmed cell death by apoptosis of metanephric nephron tubule development|down-regulation of apoptosis of metanephric nephron tubule development|down-regulation of apoptotic cell death of metanephric nephron tubule development|inhibition of type I programmed cell death of metanephric nephron tubule development|down-regulation of programmed cell death by apoptosis of metanephric nephron tubule development|negative regulation of apoptotic process of metanephric nephron tubule development|downregulation of apoptotic process of metanephric nephron tubule development|inhibition of programmed cell death by apoptosis of metanephric nephron tubule development|down regulation of apoptotic programmed cell death of metanephric nephron tubule development|down regulation of apoptotic cell death of metanephric nephron tubule development|inhibition of apoptotic process of metanephric nephron tubule development|negative regulation of programmed cell death by apoptosis of metanephric nephron tubule development|downregulation of signaling (initiator) caspase activity of metanephric nephron tubule development|down-regulation of apoptotic process of metanephric nephron tubule development|negative regulation of apoptotic program of metanephric nephron tubule development|down-regulation of signaling (initiator) caspase activity of metanephric nephron tubule development|negative regulation of apoptotic programmed cell death of metanephric nephron tubule development|down regulation of programmed cell death by apoptosis of metanephric nephron tubule development|down regulation of apoptotic program of metanephric nephron tubule development|down regulation of apoptosis of metanephric nephron tubule development|negative regulation of apoptotic cell death of metanephric nephron tubule development|inhibition of apoptotic process involved in metanephric nephron tubule development|downregulation of apoptotic program of metanephric nephron tubule development|downregulation of apoptosis of metanephric nephron tubule development|down-regulation of apoptotic program of metanephric nephron tubule development|down regulation of signaling (initiator) caspase activity of metanephric nephron tubule development|down regulation of apoptotic process of metanephric nephron tubule development|down-regulation of apoptotic programmed cell death of metanephric nephron tubule development|negative regulation of type I programmed cell death of metanephric nephron tubule development|negative regulation of signaling (initiator) caspase activity of metanephric nephron tubule development|downregulation of apoptotic cell death of metanephric nephron tubule development|downregulation of type I programmed cell death of metanephric nephron tubule development|down regulation of apoptotic process involved in metanephric nephron tubule development|down-regulation of apoptotic process involved in metanephric nephron tubule development|negative regulation of apoptosis of metanephric nephron tubule development|inhibition of apoptosis of metanephric nephron tubule development|downregulation of apoptotic process involved in metanephric nephron tubule development|inhibition of apoptotic cell death of metanephric nephron tubule development|inhibition of apoptotic program of metanephric nephron tubule development|down regulation of type I programmed cell death of metanephric nephron tubule development|inhibition of signaling (initiator) caspase activity of metanephric nephron tubule development|down-regulation of type I programmed cell death of metanephric nephron tubule development							yaf	2012-03-22T10:54:01Z					biological_process											owl:Class	
GO:1900217	biolink:NamedThing	regulation of apoptotic process involved in metanephric nephron tubule development	Any process that modulates the frequency, rate or extent of apoptotic process involved in metanephric nephron tubule development.	tmpzr1t_l9r_go_relaxed.owl	regulation of apoptotic process of metanephric nephron tubule development|regulation of apoptotic cell death of metanephric nephron tubule development|regulation of apoptosis of metanephric nephron tubule development|regulation of apoptotic programmed cell death of metanephric nephron tubule development|regulation of signaling (initiator) caspase activity of metanephric nephron tubule development|regulation of programmed cell death by apoptosis of metanephric nephron tubule development|regulation of type I programmed cell death of metanephric nephron tubule development|regulation of apoptotic program of metanephric nephron tubule development							yaf	2012-03-22T10:53:51Z					biological_process											owl:Class	
GO:0070464	biolink:NamedThing	alphav-beta3 integrin-collagen alpha3(VI) complex	A protein complex that consists of an alphav-beta3 integrin complex bound to the alpha3 chain of type VI collagen; the integrin binds most strongly to unfolded collagen.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:2000733	biolink:NamedThing	regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation	Any process that modulates the frequency, rate or extent of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation.	tmpzr1t_l9r_go_relaxed.owl	regulation of glial cell-derived neurotrophic factor receptor signaling pathway of ureteric bud formation|regulation of glial cell line-derived neurotrophic factor receptor signalling pathway of ureteric bud formation|regulation of glial cell derived neurotrophic factor receptor signaling pathway of ureteric bud formation|regulation of GDNF receptor signaling pathway of ureteric bud formation|regulation of glial cell-derived neurotrophic factor receptor signalling pathway of ureteric bud formation							yaf	2011-06-13T11:14:40Z					biological_process											owl:Class	
GO:0005628	biolink:NamedThing	prospore membrane	The prospore membrane is a double-membraned structure that extends from the cytoplasmic face of the spindle pole bodies to encompass the spindle pole bodies and the four nuclear lobes that are formed during meiosis. It helps isolate the meiotic nuclei from the cytoplasm during spore formation and serves as a foundation for the formation of the spore walls. An example of this component is found in Schizosaccharomyces pombe.	tmpzr1t_l9r_go_relaxed.owl	ascospore-type prospore membrane|FSM|forespore membrane													cellular_component											owl:Class	
GO:0032896	biolink:NamedThing	palmitoyl-CoA 9-desaturase activity	Catalysis of the reaction: palmitoyl-CoA + AH2 + O2 = palmitoleic acid (16:1delta9) + A + 2 H2O.	tmpzr1t_l9r_go_relaxed.owl	palmitoyl-CoA delta9-desaturase acitivity													molecular_function											owl:Class	
GO:0016215	biolink:NamedThing	acyl-CoA desaturase activity	Catalysis of the reaction: acyl-CoA + reduced acceptor + O2 = desaturated-acyl-CoA + acceptor + 2 H2O.	tmpzr1t_l9r_go_relaxed.owl	CoA desaturase activity	https://github.com/geneontology/go-ontology/issues/21108												molecular_function											owl:Class	
GO:0021895	biolink:NamedThing	cerebral cortex neuron differentiation	The process in which a relatively unspecialized cell acquires specialized features of a neuron residing in the cerebral cortex.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0050279	biolink:NamedThing	sepiapterin deaminase activity	Catalysis of the reaction: sepiapterin + H2O = xanthopterin-B2 + NH3.	tmpzr1t_l9r_go_relaxed.owl	sepiapterin aminohydrolase activity				MetaCyc:SEPIAPTERIN-DEAMINASE-RXN|RHEA:14025|EC:3.5.4.24									molecular_function											owl:Class	
GO:0042085	biolink:NamedThing	5-methyltetrahydropteroyltri-L-glutamate-dependent methyltransferase activity	Catalysis of the transfer of a methyl group to an acceptor molecule; dependent on the presence of 5-methyltetrahydropteroyltri-L-glutamate.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0106165	biolink:NamedThing	negative regulation of exonucleolytic catabolism of deadenylated mRNA	Any process that stops, prevents, or reduces the frequency, rate or extent of exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay.	tmpzr1t_l9r_go_relaxed.owl								hjd	2019-01-15T15:42:13Z					biological_process											owl:Class	
GO:0090295	biolink:NamedThing	nitrogen catabolite repression of transcription	A transcription regulation process in which the presence of one nitrogen source leads to a decrease in the frequency, rate, or extent of transcription of specific genes involved in the metabolism of other nitrogen sources.	tmpzr1t_l9r_go_relaxed.owl	nitrogen catabolite repression|negative regulation of transcription by nitrogen catabolites							tb	2010-02-24T02:31:53Z					biological_process											owl:Class	
GO:0002623	biolink:NamedThing	negative regulation of B cell antigen processing and presentation	Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell antigen processing and presentation.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of B lymphocyte antigen processing and presentation|negative regulation of B-cell antigen processing and presentation|negative regulation of B-lymphocyte antigen processing and presentation|downregulation of B cell antigen processing and presentation|inhibition of B cell antigen processing and presentation|down regulation of B cell antigen processing and presentation|down-regulation of B cell antigen processing and presentation													biological_process											owl:Class	
GO:0102735	biolink:NamedThing	trihydroxybenzophenone synthase activity	Catalysis of the reaction: benzoyl-CoA + 3 malonyl-CoA + 3 H+ = 2,4,6-trihydroxybenzophenone + 4 coenzyme A + 3 carbon dioxide.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-7481|RHEA:35143|EC:2.3.1.220									molecular_function											owl:Class	
GO:0015493	biolink:NamedThing	lysine:proton symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: lysine(out) + H+(out) = lysine(in) + H+(in).	tmpzr1t_l9r_go_relaxed.owl	lysine:hydrogen symporter activity													molecular_function											owl:Class	
GO:0001042	biolink:NamedThing	RNA polymerase I core binding	Binding to a RNA polymerase I core enzyme, a multisubunit eukaryotic nuclear RNA polymerase typically composed of seventeen subunits.	tmpzr1t_l9r_go_relaxed.owl								krc	2010-09-23T01:39:23Z					molecular_function											owl:Class	
GO:0071955	biolink:NamedThing	recycling endosome to Golgi transport	The directed movement of substances from recycling endosomes to the Golgi.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-10-08T01:19:00Z					biological_process											owl:Class	
GO:0042147	biolink:NamedThing	retrograde transport, endosome to Golgi	The directed movement of membrane-bounded vesicles from endosomes back to the trans-Golgi network where they are recycled for further rounds of transport.	tmpzr1t_l9r_go_relaxed.owl	retrograde (endosome to Golgi) transport													biological_process											owl:Class	
GO:1902747	biolink:NamedThing	negative regulation of lens fiber cell differentiation	Any process that stops, prevents or reduces the frequency, rate or extent of lens fiber cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	downregulation of lens fibre cell differentiation|inhibition of lens fiber cell differentiation|down regulation of lens fiber cell differentiation|down regulation of lens fibre cell differentiation|negative regulation of lens fibre cell differentiation|down-regulation of lens fibre cell differentiation|downregulation of lens fiber cell differentiation|inhibition of lens fibre cell differentiation|down-regulation of lens fiber cell differentiation							mr	2014-03-03T23:19:32Z					biological_process											owl:Class	
GO:1902753	biolink:NamedThing	negative regulation of renal amino acid absorption	Any process that stops, prevents or reduces the frequency, rate or extent of renal amino acid absorption.	tmpzr1t_l9r_go_relaxed.owl	inhibition of renal amino acid absorption|downregulation of renal amino acid absorption|down-regulation of renal amino acid absorption|down regulation of renal amino acid absorption							hjd	2014-03-05T15:44:01Z					biological_process											owl:Class	
GO:1905032	biolink:NamedThing	negative regulation of membrane repolarization during cardiac muscle cell action potential	Any process that stops, prevents or reduces the frequency, rate or extent of membrane repolarization during cardiac muscle cell action potential.	tmpzr1t_l9r_go_relaxed.owl	inhibition of membrane repolarization during cardiac muscle cell action potential|downregulation of membrane repolarization during cardiac muscle cell action potential|down regulation of membrane repolarization during cardiac muscle cell action potential|down-regulation of membrane repolarization during cardiac muscle cell action potential							rph	2016-03-07T10:24:44Z					biological_process											owl:Class	
GO:2000057	biolink:NamedThing	negative regulation of Wnt signaling pathway involved in digestive tract morphogenesis	Any process that stops, prevents, or reduces the frequency, rate or extent of Wnt signaling pathway involved in digestive tract morphogenesis.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of Wnt receptor signaling pathway involved in digestive tract morphogenesis|negative regulation of Wnt receptor signalling pathway involved in digestive tract morphogenesis|negative regulation of Wnt-activated signaling pathway involved in digestive tract morphogenesis							jl	2010-08-20T01:17:35Z					biological_process											owl:Class	
GO:0043993	biolink:NamedThing	histone acetyltransferase activity (H3-K18 specific)	Catalysis of the reaction: acetyl-CoA + histone H3 L-lysine (position 18) = CoA + histone H3 N6-acetyl-L-lysine (position 18).	tmpzr1t_l9r_go_relaxed.owl	histone lysine N-acetyltransferase activity (H3-K18 specific)													molecular_function											owl:Class	
GO:0035350	biolink:NamedThing	FAD transmembrane transport	The process in which flavin-adenine dinucleotide (FAD) is transported across a membrane. FAD forms the coenzyme of the prosthetic group of various flavoprotein oxidoreductase enzymes, in which it functions as an electron acceptor by being reversibly converted to its reduced form.	tmpzr1t_l9r_go_relaxed.owl	FAD membrane transport					Note that this term is not intended for use in annotating lateral movement within membranes.		bf	2010-03-04T03:45:11Z					biological_process											owl:Class	
GO:0050893	biolink:NamedThing	sensory processing	Any neural process required for an organism to sense and interpret the dimensions of a sensory experience: modality, location, intensity and affect.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0050890	biolink:NamedThing	cognition	The operation of the mind by which an organism becomes aware of objects of thought or perception; it includes the mental activities associated with thinking, learning, and memory.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Cognition									biological_process											owl:Class	
GO:0004729	biolink:NamedThing	oxygen-dependent protoporphyrinogen oxidase activity	Catalysis of the reaction: 3 O(2) + protoporphyrinogen IX = 3 H(2)O(2) + protoporphyrin IX.	tmpzr1t_l9r_go_relaxed.owl	protoporphyrinogen-IX:oxygen oxidoreductase activity				EC:1.3.3.4|MetaCyc:PROTOPORGENOXI-RXN|KEGG_REACTION:R03222|RHEA:25576|Reactome:R-HSA-189423									molecular_function											owl:Class	
GO:0070818	biolink:NamedThing	protoporphyrinogen oxidase activity	Catalysis of the reaction: protoporphyrinogen IX + acceptor = protoporphyrin IX + reduced acceptor.	tmpzr1t_l9r_go_relaxed.owl	protoporphyrinogenase activity|protoporphyrinogen IX oxidase activity|protoporphyrinogen-IX oxidase activity							mah	2009-07-20T02:41:12Z					molecular_function											owl:Class	
GO:0061512	biolink:NamedThing	protein localization to cilium	A process in which a protein is transported to, or maintained in, a location within a cilium.	tmpzr1t_l9r_go_relaxed.owl								dph	2013-03-22T15:41:44Z					biological_process											owl:Class	
GO:1900792	biolink:NamedThing	shamixanthone catabolic process	The chemical reactions and pathways resulting in the breakdown of shamixanthone.	tmpzr1t_l9r_go_relaxed.owl	shamixanthone catabolism|shamixanthone degradation|shamixanthone breakdown							di	2012-06-04T09:40:42Z					biological_process											owl:Class	
GO:0032223	biolink:NamedThing	negative regulation of synaptic transmission, cholinergic	Any process that stops, prevents, or reduces the frequency, rate or extent of cholinergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter acetylcholine.	tmpzr1t_l9r_go_relaxed.owl	downregulation of synaptic transmission, cholinergic|down regulation of synaptic transmission, cholinergic|down-regulation of synaptic transmission, cholinergic|inhibition of synaptic transmission, cholinergic													biological_process											owl:Class	
GO:1905337	biolink:NamedThing	positive regulation of aggrephagy	Any process that activates or increases the frequency, rate or extent of aggrephagy.	tmpzr1t_l9r_go_relaxed.owl	activation of aggrephagy|up regulation of aggrephagy|upregulation of aggrephagy|up-regulation of aggrephagy							pad	2016-07-26T13:42:02Z					biological_process											owl:Class	
GO:1905335	biolink:NamedThing	regulation of aggrephagy	Any process that modulates the frequency, rate or extent of aggrephagy.	tmpzr1t_l9r_go_relaxed.owl								pad	2016-07-26T13:41:46Z					biological_process											owl:Class	
GO:0000774	biolink:NamedThing	adenyl-nucleotide exchange factor activity	Binds to and stimulates the hydrolysis and exchange of adenyl nucleotides by other proteins.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-5252079									molecular_function											owl:Class	
GO:0060590	biolink:NamedThing	ATPase regulator activity	Binds to and modulates the activity of an ATP hydrolysis activity.	tmpzr1t_l9r_go_relaxed.owl	ATP hydrolysis regulator activity	https://github.com/geneontology/go-ontology/issues/20955						dph	2009-05-08T02:49:24Z					molecular_function											owl:Class	
GO:0046451	biolink:NamedThing	diaminopimelate metabolic process	The chemical reactions and pathways involving diaminopimelate, the anion of the dicarboxylic acid 2,6-diaminoheptanedioic acid. It is an intermediate in lysine biosynthesis and as a component (as meso-diaminopimelate) of the peptidoglycan of Gram-negative bacterial cell walls.	tmpzr1t_l9r_go_relaxed.owl	diaminopimelate metabolism													biological_process											owl:Class	
GO:0002731	biolink:NamedThing	negative regulation of dendritic cell cytokine production	Any process that stops, prevents, or reduces the frequency, rate, or extent of dendritic cell cytokine production.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of dendritic cell cytokine production|down regulation of dendritic cell cytokine production|downregulation of dendritic cell cytokine production|inhibition of dendritic cell cytokine production													biological_process											owl:Class	
GO:0044716	biolink:NamedThing	8-oxo-GDP phosphatase activity	Catalysis of the reaction 8-oxo-GDP + H2O = 8-oxo-GMP + phosphate.	tmpzr1t_l9r_go_relaxed.owl					EC:3.6.1.58|RHEA:62356			jl	2012-10-18T13:32:39Z					molecular_function											owl:Class	
GO:0017110	biolink:NamedThing	nucleoside-diphosphatase activity	Catalysis of the reaction: a nucleoside diphosphate + H2O = a nucleoside monophosphate  + phosphate.	tmpzr1t_l9r_go_relaxed.owl	inosine diphosphatase|nucleoside diphosphate phosphohydrolase activity|nucleoside diphosphate phosphatase activity|type L nucleoside diphosphatase|apyrase activity|nucleoside-diphosphate phosphohydrolase activity|nucleoside 5'-diphosphatase activity|nucleoside diphosphatase activity|type B nucleoside diphosphatase|inosine 5'-diphosphatase|NDPase activity				Reactome:R-HSA-8850854|Reactome:R-HSA-2395876|Reactome:R-HSA-8851396|Reactome:R-HSA-8851129|MetaCyc:NUCLEOSIDE-DIPHOSPHATASE-RXN|EC:3.6.1.6|Reactome:R-HSA-8851550|Reactome:R-HSA-8851225|RHEA:36799|Reactome:R-HSA-8851356									molecular_function											owl:Class	
GO:0032928	biolink:NamedThing	regulation of superoxide anion generation	Any process that modulates the frequency, rate or extent of enzymatic generation of superoxide by a cell.	tmpzr1t_l9r_go_relaxed.owl	regulation of superoxide release													biological_process											owl:Class	
GO:0016008	biolink:NamedThing	major mitochondrial derivative	The larger of the two mitochondrial derivatives that arise by the unfolding of the Nebenkern during flagellum elongation; the major mitochondrial derivative is ovoid and darker than the minor derivative.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/20737												cellular_component											owl:Class	
GO:0016007	biolink:NamedThing	mitochondrial derivative	The major and minor mitochondrial derivatives are the mitochondria of the sperm tail and derive by the unfolding of the Nebenkern during flagellum elongation.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/20737												cellular_component											owl:Class	
GO:2000042	biolink:NamedThing	negative regulation of double-strand break repair via homologous recombination	Any process that stops, prevents, or reduces the frequency, rate or extent of double-strand break repair via homologous recombination.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of HDR|negative regulation of HRR|negative regulation of Rad51-dependent recombinational repair|negative regulation of homologous recombinational repair|negative regulation of Rhp51-dependent recombinational repair|negative regulation of homology-directed repair							tb	2010-08-19T06:37:08Z					biological_process											owl:Class	
GO:0071086	biolink:NamedThing	alphaIIb-beta3 integrin-CD9-CD47-platelet glycoprotein Ib complex	A protein complex that consists of an alphaIIb-beta3 integrin complex bound to the cell surface proteins CD9 and CD47, and the heterodimeric platelet glycoprotein Ib.	tmpzr1t_l9r_go_relaxed.owl	ITGA2b-ITGB3-CD9-GP1b-CD47 complex							mah	2009-11-06T04:45:08Z					cellular_component											owl:Class	
GO:0090665	biolink:NamedThing	glycoprotein complex	A protein complex containing at least one glycosylated protein, may be held together by both covalent and noncovalent bonds.	tmpzr1t_l9r_go_relaxed.owl						An example is the Dictyostelium multi protein pspB complex, which is secreted from prespore vesicles and incorporated into the spore coat.		tb	2015-12-11T17:45:23Z					cellular_component											owl:Class	
GO:1900264	biolink:NamedThing	positive regulation of DNA-directed DNA polymerase activity	Any process that activates or increases the frequency, rate or extent of DNA-directed DNA polymerase activity.	tmpzr1t_l9r_go_relaxed.owl	up regulation of deoxyribonucleic acid duplicase activity|positive regulation of DNA replicase activity|up regulation of DNA polymerase gamma|up-regulation of sequenase|up regulation of nu DNA polymerase activity|positive regulation of sigma DNA polymerase activity|positive regulation of theta DNA polymerase activity|positive regulation of epsilon DNA polymerase activity|up-regulation of iota DNA polymerase activity|activation of zeta DNA polymerase activity|up-regulation of alpha DNA polymerase activity|activation of duplicase|up regulation of DNA-dependent DNA polymerase activity|up-regulation of Taq Pol I|activation of DNA polymerase I|up-regulation of epsilon DNA polymerase activity|up regulation of iota DNA polymerase activity|upregulation of theta DNA polymerase activity|positive regulation of deoxyribonucleic duplicase activity|up regulation of DNA polymerase beta|upregulation of deoxyribonucleic acid duplicase activity|positive regulation of iota DNA polymerase activity|upregulation of DNA polymerase alpha|upregulation of alpha DNA polymerase activity|positive regulation of DNA polymerase I|activation of DNA polymerase V activity|up regulation of kappa DNA polymerase activity|up-regulation of deoxyribonucleic duplicase activity|positive regulation of DNA polymerase gamma|upregulation of kappa DNA polymerase activity|positive regulation of sequenase|up-regulation of lambda DNA polymerase activity|up-regulation of delta DNA polymerase activity|activation of Taq Pol I|upregulation of deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (DNA-directed) activity|positive regulation of eta DNA polymerase activity|activation of gamma DNA-directed DNA polymerase activity|activation of DNA polymerase gamma|upregulation of DNA polymerase gamma|up regulation of sequenase|activation of sequenase|upregulation of zeta DNA polymerase activity|upregulation of DNA-dependent DNA polymerase activity|activation of eta DNA polymerase activity|up-regulation of DNA nucleotidyltransferase (DNA-directed) activity|up regulation of deoxyribonucleic polymerase I|activation of DNA-dependent DNA polymerase activity|up regulation of zeta DNA polymerase activity|up-regulation of Klenow fragment|positive regulation of duplicase|upregulation of sequenase|up regulation of DNA replicase activity|up regulation of DNA nucleotidyltransferase (DNA-directed) activity|positive regulation of beta DNA polymerase activity|positive regulation of deoxyribonucleic acid duplicase activity|up regulation of Taq DNA polymerase|up-regulation of nu DNA polymerase activity|upregulation of DNA-directed DNA polymerase activity|up-regulation of zeta DNA polymerase activity|positive regulation of DNA polymerase beta|positive regulation of DNA nucleotidyltransferase (DNA-directed) activity|activation of Taq DNA polymerase|up-regulation of DNA polymerase beta|positive regulation of lambda DNA polymerase activity|up-regulation of DNA duplicase activity|up regulation of Taq Pol I|upregulation of DNA replicase activity|activation of Klenow fragment|up-regulation of kappa DNA polymerase activity|activation of DNA polymerase alpha|upregulation of deoxyribonucleic polymerase I|upregulation of sigma DNA polymerase activity|up-regulation of Tca DNA polymerase|up-regulation of beta DNA polymerase activity|positive regulation of nu DNA polymerase activity|activation of nu DNA polymerase activity|upregulation of deoxyribonucleic duplicase activity|upregulation of DNA nucleotidyltransferase (DNA-directed) activity|upregulation of DNA polymerase III|upregulation of DNA polymerase V activity|up regulation of Tca DNA polymerase|up regulation of DNA polymerase II|up regulation of DNA duplicase activity|activation of beta DNA polymerase activity|up-regulation of DNA replicase activity|up regulation of deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (DNA-directed) activity|positive regulation of Klenow fragment|activation of iota DNA polymerase activity|activation of deoxyribonucleic duplicase activity|up regulation of alpha DNA polymerase activity|up regulation of DNA polymerase III|upregulation of gamma DNA-directed DNA polymerase activity|positive regulation of kappa DNA polymerase activity|up regulation of gamma DNA-directed DNA polymerase activity|positive regulation of gamma DNA-directed DNA polymerase activity|up-regulation of sigma DNA polymerase activity|positive regulation of deoxyribonucleic polymerase I|upregulation of mu DNA polymerase activity|up-regulation of DNA-directed DNA polymerase activity|activation of theta DNA polymerase activity|positive regulation of DNA polymerase III|up regulation of duplicase|up regulation of deoxyribonucleic duplicase activity|up regulation of Klenow fragment|up-regulation of eta DNA polymerase activity|activation of DNA-directed DNA polymerase activity|upregulation of iota DNA polymerase activity|up-regulation of gamma DNA-directed DNA polymerase activity|activation of DNA polymerase II|activation of DNA polymerase III|upregulation of DNA polymerase II|upregulation of duplicase|upregulation of Tca DNA polymerase|positive regulation of DNA polymerase V activity|up-regulation of deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (DNA-directed) activity|activation of delta DNA polymerase activity|up-regulation of DNA polymerase V activity|up-regulation of deoxyribonucleic polymerase I|upregulation of beta DNA polymerase activity|positive regulation of zeta DNA polymerase activity|positive regulation of deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (DNA-directed) activity|up regulation of lambda DNA polymerase activity|upregulation of DNA polymerase beta|upregulation of Taq Pol I|up regulation of DNA polymerase alpha|activation of sigma DNA polymerase activity|up-regulation of DNA polymerase I|up regulation of eta DNA polymerase activity|upregulation of eta DNA polymerase activity|up regulation of mu DNA polymerase activity|upregulation of DNA polymerase I|up regulation of DNA polymerase V activity|activation of deoxyribonucleic polymerase I|up-regulation of DNA polymerase II|activation of kappa DNA polymerase activity|up-regulation of DNA-dependent DNA polymerase activity|up regulation of beta DNA polymerase activity|activation of epsilon DNA polymerase activity|activation of deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (DNA-directed) activity|positive regulation of Taq DNA polymerase|positive regulation of delta DNA polymerase activity|activation of DNA nucleotidyltransferase (DNA-directed) activity|activation of lambda DNA polymerase activity|up regulation of delta DNA polymerase activity|up regulation of theta DNA polymerase activity|upregulation of delta DNA polymerase activity|upregulation of DNA duplicase activity|up regulation of DNA polymerase I|upregulation of lambda DNA polymerase activity|upregulation of nu DNA polymerase activity|up-regulation of theta DNA polymerase activity|activation of DNA polymerase beta|up regulation of epsilon DNA polymerase activity|activation of Tca DNA polymerase|up-regulation of duplicase|activation of mu DNA polymerase activity|activation of DNA replicase activity|activation of deoxyribonucleic acid duplicase activity|activation of alpha DNA polymerase activity|upregulation of Klenow fragment|positive regulation of Taq Pol I|up-regulation of mu DNA polymerase activity|positive regulation of DNA-dependent DNA polymerase activity|up-regulation of Taq DNA polymerase|up-regulation of DNA polymerase III|positive regulation of DNA polymerase alpha|up-regulation of DNA polymerase alpha|up regulation of DNA-directed DNA polymerase activity|positive regulation of Tca DNA polymerase|activation of DNA duplicase activity|positive regulation of alpha DNA polymerase activity|up-regulation of DNA polymerase gamma|upregulation of epsilon DNA polymerase activity|up regulation of sigma DNA polymerase activity|positive regulation of DNA polymerase II|positive regulation of DNA duplicase activity|positive regulation of mu DNA polymerase activity|up-regulation of deoxyribonucleic acid duplicase activity|upregulation of Taq DNA polymerase							tb	2012-04-03T11:07:27Z					biological_process											owl:Class	
GO:1990047	biolink:NamedThing	spindle matrix	A proteinaceous, nuclear-derived structure that embeds the microtubule spindle apparatus from pole to pole in a microtubule-independent manner during mitosis.	tmpzr1t_l9r_go_relaxed.owl								pr	2013-02-18T08:51:47Z					cellular_component											owl:Class	
GO:0001914	biolink:NamedThing	regulation of T cell mediated cytotoxicity	Any process that modulates the frequency, rate, or extent of T cell mediated cytotoxicity.	tmpzr1t_l9r_go_relaxed.owl	regulation of T-cell mediated cytolysis|regulation of T-cell mediated cell killing|regulation of T cell mediated apoptosis|regulation of T lymphocyte mediated cytotoxicity|regulation of T-cell mediated cell death|regulation of T cell mediated cell death|regulation of T-cell mediated apoptosis|regulation of T-cell mediated cytotoxicity|regulation of T cell mediated cytolysis|regulation of T cell mediated cell killing|regulation of T-lymphocyte mediated cytotoxicity													biological_process											owl:Class	
GO:0002709	biolink:NamedThing	regulation of T cell mediated immunity	Any process that modulates the frequency, rate, or extent of T cell mediated immunity.	tmpzr1t_l9r_go_relaxed.owl	regulation of T lymphocyte mediated immunity|regulation of T-cell mediated immunity|regulation of T-lymphocyte mediated immunity													biological_process											owl:Class	
GO:0150195	biolink:NamedThing	transport across blood-cerebrospinal fluid barrier	The directed movement of substances (e.g. macromolecules, small molecules, ions) through the blood-cerebrospinal fluid barrier.	tmpzr1t_l9r_go_relaxed.owl	transport across BCSFB|transport across blood/CSF barrier|transport across blood/cerebrospinal fluid barrier|transport across blood-CSF barrier							bc	2020-03-26T14:43:04Z					biological_process											owl:Class	
GO:0010232	biolink:NamedThing	vascular transport	The directed movement of substances, into, out of or within a cell, either in a vascular tissue or in the vascular membrane.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0061268	biolink:NamedThing	mesonephric interstitial fibroblast fate commitment	The process in which the developmental fate of a cell becomes restricted such that it will develop into a mesonephric interstitial fibroblast.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-08-30T03:16:52Z					biological_process											owl:Class	
GO:0045799	biolink:NamedThing	positive regulation of chromatin assembly or disassembly	Any process that activates or increases the frequency, rate or extent of chromatin assembly or disassembly.	tmpzr1t_l9r_go_relaxed.owl	activation of chromatin assembly or disassembly|up-regulation of chromatin assembly or disassembly|positive regulation of chromatin assembly/disassembly|stimulation of chromatin assembly or disassembly|up regulation of chromatin assembly or disassembly|upregulation of chromatin assembly or disassembly													biological_process											owl:Class	
GO:1905269	biolink:NamedThing	positive regulation of chromatin organization	Any process that activates or increases the frequency, rate or extent of chromatin organization.	tmpzr1t_l9r_go_relaxed.owl	up regulation of establishment or maintenance of chromatin architecture|positive regulation of chromatin modification|up regulation of chromatin organisation|up-regulation of establishment or maintenance of chromatin architecture|up regulation of chromatin organization|up-regulation of chromatin organization|activation of chromatin organization|positive regulation of establishment or maintenance of chromatin architecture|positive regulation of chromatin organisation|upregulation of chromatin organisation|upregulation of establishment or maintenance of chromatin architecture|activation of establishment or maintenance of chromatin architecture|upregulation of chromatin organization|activation of chromatin organisation|up-regulation of chromatin organisation							pr	2016-06-15T20:14:56Z			GO:1903310		biological_process											owl:Class	
GO:0004660	biolink:NamedThing	protein farnesyltransferase activity	Catalysis of the reaction: farnesyl diphosphate + protein-cysteine = S-farnesyl protein + diphosphate.	tmpzr1t_l9r_go_relaxed.owl	CAAX farnesyltransferase activity|protein-cysteine farnesyltransferase activity|farnesyl-diphosphate:protein-cysteine farnesyltransferase activity|FTase activity				Reactome:R-HSA-9647978|Reactome:R-HSA-2530501|RHEA:13345|MetaCyc:2.5.1.58-RXN|EC:2.5.1.58	The catalyzed reaction transfers a farnesyl group from farnesyl diphosphate to a target protein.  There is no relationship between this activity and farnesyltransferase activity, GO:0004311, where the catalyzed reaction forms (free) geranylgeranyl diphosphate.						GO:0018223		molecular_function											owl:Class	
GO:0008318	biolink:NamedThing	protein prenyltransferase activity	Catalysis of the covalent addition of an isoprenoid group such as a farnesyl or geranylgeranyl group via thioether linkages to a cysteine residue in a protein.	tmpzr1t_l9r_go_relaxed.owl												GO:0008244		molecular_function											owl:Class	
GO:1990341	biolink:NamedThing	thrombospondin complex	A homotrimeric or homopentameric glycoprotein that functions at the interface of the cell membrane and the extracellular matrix through its interactions with proteins and proteoglycans, such as collagens, integrins and fibronectin, to regulate matrix structure and cellular behaviour.	tmpzr1t_l9r_go_relaxed.owl								bhm	2014-03-21T14:27:07Z					cellular_component											owl:Class	
GO:0102923	biolink:NamedThing	3'-N-debenzoyl-2'-deoxytaxol N-benzoyltransferase activity	Catalysis of the reaction: 3'-N-debenzoyltaxol + benzoyl-CoA = H+ + paclitaxel + coenzyme A.	tmpzr1t_l9r_go_relaxed.owl					RHEA:33687|MetaCyc:RXN-8859									molecular_function											owl:Class	
GO:0035647	biolink:NamedThing	3-oxo-delta(4,5)-steroid 5-beta-reductase activity	Catalysis of the reaction: a 3-oxo-delta-4,5-steroid + NADPH + H(+) = a 5-beta-3-oxo-steroid + NADP(+).	tmpzr1t_l9r_go_relaxed.owl	3-oxo-delta4,5-steroid 5beta-reductase							bf	2011-01-24T01:31:30Z					molecular_function											owl:Class	
GO:0042814	biolink:NamedThing	monopolar cell growth	Polarized growth from one end of a cell.	tmpzr1t_l9r_go_relaxed.owl	monopolar cell elongation|polar cell elongation|monopolar growth													biological_process											owl:Class	
GO:0009826	biolink:NamedThing	unidimensional cell growth	The process in which a cell irreversibly increases in size in one [spatial] dimension or along one axis, resulting in the morphogenesis of the cell.	tmpzr1t_l9r_go_relaxed.owl	cell elongation|cell growth along one axis|polar cell growth|cell growth in one dimension|cell morphogenesis by unidimensional growth|polarized cell growth					Unidimensional cell growth refers to a change in both cell size and cell shape. For cell shape changes where cell size is not affected, consider instead the term 'regulation of cell shape ; GO:0008360' and its children.								biological_process											owl:Class	
GO:0071746	biolink:NamedThing	IgA immunoglobulin complex, circulating	A protein complex composed of two identical immunoglobulin heavy chains of an IgA isotype and two identical immunoglobulin light chains, held together by disulfide bonds, sometimes complexed with J chain or J chain and secretory component, and present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.	tmpzr1t_l9r_go_relaxed.owl	IgA2 antibody|IgA antibody|IgA1 antibody					Note that an IgA immunoglobulin complex has the function of antigen binding if a suitable antigen is available.		mah	2010-03-24T01:44:53Z					cellular_component											owl:Class	
GO:0042571	biolink:NamedThing	immunoglobulin complex, circulating	An immunoglobulin complex that is secreted into extracellular space and found in mucosal areas or other tissues or circulating in the blood or lymph. In its canonical form, a circulating immunoglobulin complex is composed of two identical heavy chains and two identical light chains, held together by disulfide bonds. Some forms of are polymers of the basic structure and contain additional components such as J-chain and the secretory component.	tmpzr1t_l9r_go_relaxed.owl	antibody				Wikipedia:Antibody	Note that an immunoglobulin complex has the function of antigen binding if a suitable antigen is available.								cellular_component											owl:Class	
GO:1903207	biolink:NamedThing	regulation of hydrogen peroxide-induced neuron death	Any process that modulates the frequency, rate or extent of hydrogen peroxide-induced neuron death.	tmpzr1t_l9r_go_relaxed.owl	regulation of neuronal cell death in response to hydrogen peroxide|regulation of neuron death in response to hydrogen peroxide|regulation of neuron death in response to H2O2							bf	2014-07-21T16:27:05Z					biological_process											owl:Class	
GO:1903205	biolink:NamedThing	regulation of hydrogen peroxide-induced cell death	Any process that modulates the frequency, rate or extent of hydrogen peroxide-induced cell death.	tmpzr1t_l9r_go_relaxed.owl	regulation of cell death in response to H2O2|regulation of hydrogen peroxide-mediated cell death|regulation of cell death in response to hydrogen peroxide|protection against hydrogen peroxide-mediated cell death							bf	2014-07-21T16:21:47Z					biological_process											owl:Class	
GO:0045774	biolink:NamedThing	negative regulation of beta 2 integrin biosynthetic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of beta 2 integrins.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of beta 2 integrin biosynthesis|down-regulation of beta 2 integrin biosynthetic process|inhibition of beta 2 integrin biosynthetic process|negative regulation of beta 2 integrin synthesis|negative regulation of beta 2 integrin anabolism|downregulation of beta 2 integrin biosynthetic process|negative regulation of beta 2 integrin formation|down regulation of beta 2 integrin biosynthetic process													biological_process											owl:Class	
GO:0045720	biolink:NamedThing	negative regulation of integrin biosynthetic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of integrins.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of integrin anabolism|downregulation of integrin biosynthetic process|negative regulation of integrin synthesis|inhibition of integrin biosynthetic process|down regulation of integrin biosynthetic process|negative regulation of integrin formation|down-regulation of integrin biosynthetic process|negative regulation of integrin biosynthesis													biological_process											owl:Class	
GO:0034110	biolink:NamedThing	regulation of homotypic cell-cell adhesion	Any process that modulates the frequency, rate, or extent of homotypic cell-cell adhesion.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0010543	biolink:NamedThing	regulation of platelet activation	Any process that modulates the rate or frequency of platelet activation. Platelet activation is a series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0050865	biolink:NamedThing	regulation of cell activation	Any process that modulates the frequency, rate or extent of cell activation, the change in the morphology or behavior of a cell resulting from exposure to an activating factor such as a cellular or soluble ligand.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0010050	biolink:NamedThing	vegetative phase change	Any process involved in the transition of a plant from a juvenile phase of vegetative development to an adult phase of vegetative development.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0042101	biolink:NamedThing	T cell receptor complex	A protein complex that contains a disulfide-linked heterodimer of T cell receptor (TCR) chains, which are members of the immunoglobulin superfamily, and mediates antigen recognition, ultimately resulting in T cell activation. The TCR heterodimer is associated with the CD3 complex, which consists of the nonpolymorphic polypeptides gamma, delta, epsilon, zeta, and, in some cases, eta (an RNA splice variant of zeta) or Fc epsilon chains.	tmpzr1t_l9r_go_relaxed.owl	T-lymphocyte receptor complex|TCR complex|TCR|T lymphocyte receptor complex|T-cell receptor complex				Wikipedia:T_cell_receptor									cellular_component											owl:Class	
GO:1903315	biolink:NamedThing	negative regulation of nitrogen cycle metabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of nitrogen cycle metabolic process.	tmpzr1t_l9r_go_relaxed.owl	down regulation of nitrogen cycle metabolic process|down-regulation of nitrogen cycle metabolic process|inhibition of nitrogen cycle metabolic process|downregulation of nitrogen cycle metabolic process							vw	2014-08-18T12:57:42Z					biological_process											owl:Class	
GO:2000377	biolink:NamedThing	regulation of reactive oxygen species metabolic process	Any process that modulates the frequency, rate or extent of reactive oxygen species metabolic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of ROS metabolic process|regulation of reactive oxygen species metabolism							mah	2011-02-11T02:06:36Z					biological_process											owl:Class	
GO:0010880	biolink:NamedThing	regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum	Any process that modulates the rate, frequency or extent of release of sequestered calcium ion into cytosol by the sarcoplasmic reticulum, the process in which the release of sequestered calcium ion by sarcoplasmic reticulum into cytosol occurs via calcium release channels.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0097165	biolink:NamedThing	nuclear stress granule	A dense aggregation in the nucleus composed of proteins and RNAs that appear when the cell is under stress.	tmpzr1t_l9r_go_relaxed.owl								pr	2011-09-28T07:49:55Z					cellular_component											owl:Class	
GO:0035770	biolink:NamedThing	ribonucleoprotein granule	A non-membranous macromolecular complex containing proteins and translationally silenced mRNAs. RNA granules contain proteins that control the localization, stability, and translation of their RNA cargo. Different types of RNA granules (RGs) exist, depending on the cell type and cellular conditions.	tmpzr1t_l9r_go_relaxed.owl	mRNP granule|RNP granule|RNA granule							bf	2011-04-01T10:50:47Z					cellular_component											owl:Class	
GO:0031626	biolink:NamedThing	beta-endorphin binding	Binding to beta-endorphin, a peptide generated by the cleavage of pro-opiomelanocortin.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0042165	biolink:NamedThing	neurotransmitter binding	Binding to a neurotransmitter, any chemical substance that is capable of transmitting (or inhibiting the transmission of) a nerve impulse from a neuron to another cell.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0002283	biolink:NamedThing	neutrophil activation involved in immune response	The change in morphology and behavior of a neutrophil resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response.	tmpzr1t_l9r_go_relaxed.owl	neutrophil activation during immune response													biological_process											owl:Class	
GO:0042119	biolink:NamedThing	neutrophil activation	The change in morphology and behavior of a neutrophil resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0051918	biolink:NamedThing	negative regulation of fibrinolysis	Any process that stops, prevents, or reduces the frequency, rate or extent of fibrinolysis, an ongoing process that solubilizes fibrin, resulting in the removal of small blood clots.	tmpzr1t_l9r_go_relaxed.owl	inhibition of fibrinolysis|down regulation of fibrinolysis|downregulation of fibrinolysis|down-regulation of fibrinolysis													biological_process											owl:Class	
GO:0051917	biolink:NamedThing	regulation of fibrinolysis	Any process that modulates the frequency, rate or extent of fibrinolysis, an ongoing process that solubilizes fibrin, resulting in the removal of small blood clots.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0010308	biolink:NamedThing	acireductone dioxygenase (Ni2+-requiring) activity	Catalysis of the reaction: 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + O(2) = 3-(methylthio)propanoate + CO + formate.	tmpzr1t_l9r_go_relaxed.owl	2-hydroxy-3-keto-5-thiomethylpent-1-ene dioxygenase activity|ARD activity|1,2-dihydroxy-5-(methylthio)pent-1-en-3-one:oxygen oxidoreductase (formate- and CO-forming)|acireductone dioxygenase activity|E-2 activity				KEGG_REACTION:R07363|EC:1.13.11.53|MetaCyc:R146-RXN|RHEA:14161									molecular_function											owl:Class	
GO:0000922	biolink:NamedThing	spindle pole	Either of the ends of a spindle, where spindle microtubules are organized; usually contains a microtubule organizing center and accessory molecules, spindle microtubules and astral microtubules.	tmpzr1t_l9r_go_relaxed.owl												GO:0030615		cellular_component											owl:Class	
GO:0018240	biolink:NamedThing	protein S-linked glycosylation via cysteine	The glycosylation of protein via the sulfur atom of peptidyl-cysteine, forming S-glycosyl-L-cysteine.	tmpzr1t_l9r_go_relaxed.owl	protein amino acid S-linked glycosylation via cysteine				RESID:AA0152									biological_process											owl:Class	
GO:0018280	biolink:NamedThing	protein S-linked glycosylation	A protein glycosylation process in which a carbohydrate or carbohydrate derivative unit is added to a protein via a sulfur atom of a peptidyl-amino-acid such as cysteine or methionine.	tmpzr1t_l9r_go_relaxed.owl	protein amino acid S-linked glycosylation													biological_process											owl:Class	
GO:0043052	biolink:NamedThing	thermotaxis	The directed movement of a motile cell or organism in response to a temperature gradient. Movement may be towards either a higher or lower temperature.	tmpzr1t_l9r_go_relaxed.owl	taxis in response to temperature stimulus				Wikipedia:Thermotaxis									biological_process											owl:Class	
GO:0035394	biolink:NamedThing	regulation of chemokine (C-X-C motif) ligand 9 production	Any process that modulates the frequency, rate, or extent of production of chemokine (C-X-C motif) ligand 9.	tmpzr1t_l9r_go_relaxed.owl	regulation of CXCL9 production|regulation of MIG production							bf	2010-03-23T10:06:19Z					biological_process											owl:Class	
GO:0015485	biolink:NamedThing	cholesterol binding	Binding to cholesterol (cholest-5-en-3-beta-ol); the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0032934	biolink:NamedThing	sterol binding	Binding to a sterol, a steroid containing a hydroxy group in the 3 position, closely related to cholestan-3-ol.	tmpzr1t_l9r_go_relaxed.owl	sterol carrier activity											GO:0005498		molecular_function											owl:Class	
GO:0033577	biolink:NamedThing	protein glycosylation in endoplasmic reticulum	The addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid in the endoplasmic reticulum.	tmpzr1t_l9r_go_relaxed.owl	protein amino acid glycosylation in ER|core glycosylation|protein amino acid glycosylation in endoplasmic reticulum													biological_process											owl:Class	
GO:0046819	biolink:NamedThing	protein secretion by the type V secretion system	The process in which proteins mediate their own secretion across the outer membrane through a beta-barrel pore structure formed by the C-terminal domain of the protein precursor. Following passage across the outer membrane, the mature protein is released from the pore by an autocatalytic activity. Proteins secreted by the Type V system are first translocated across the plasma membrane by the Sec pathway.	tmpzr1t_l9r_go_relaxed.owl	protein secretion by the type V protein secretion system|protein secretion by the autotransporter system|autotransporter system|type V protein secretion system													biological_process											owl:Class	
GO:0098776	biolink:NamedThing	protein transport across the cell outer membrane	The directed movement of proteins across the cell outer membrane.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0098032	biolink:NamedThing	icosahedral viral capsid, collar fiber	A fiber attached to the collar structure of some icosahedral viral capsids.	tmpzr1t_l9r_go_relaxed.owl								bm	2012-07-19T15:05:16Z					cellular_component											owl:Class	
GO:0098022	biolink:NamedThing	viral capsid, fiber	A type of capsid decoration composed of fiber structures.	tmpzr1t_l9r_go_relaxed.owl	head/capsid fiber							bm	2012-07-19T11:56:32Z					cellular_component											owl:Class	
GO:0042162	biolink:NamedThing	telomeric DNA binding	Binding to a telomere, a specific structure at the end of a linear chromosome required for the integrity and maintenance of the end.	tmpzr1t_l9r_go_relaxed.owl	telomere binding|telomeric repeat binding													molecular_function											owl:Class	
GO:0043565	biolink:NamedThing	sequence-specific DNA binding	Binding to DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.	tmpzr1t_l9r_go_relaxed.owl	sequence specific DNA binding													molecular_function											owl:Class	
GO:0015450	biolink:NamedThing	protein-transporting ATPase activity	Primary active carrier-mediated transport of a protein across a membrane, driven by the hydrolysis of the diphosphate bond of inorganic pyrophosphate, ATP, or another nucleoside triphosphate. The transport protein may or may not be transiently phosphorylated, but the substrate is not phosphorylated.	tmpzr1t_l9r_go_relaxed.owl	protein translocase activity|P-P-bond-hydrolysis-driven protein transmembrane transporter activity	https://github.com/geneontology/go-ontology/issues/21271			Reactome:R-HSA-1222523									molecular_function											owl:Class	
GO:0008320	biolink:NamedThing	protein transmembrane transporter activity	Enables the transfer of a protein from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	protein channel activity				Reactome:R-HSA-5250972|Reactome:R-HSA-9636375|Reactome:R-HSA-1299475|Reactome:R-HSA-5246514|Reactome:R-HSA-5205661|Reactome:R-HSA-5210947|Reactome:R-HSA-184269|Reactome:R-HSA-1268022|Reactome:R-HSA-3149434|Reactome:R-HSA-5250616|Reactome:R-HSA-5336420|Reactome:R-HSA-5244506|Reactome:R-HSA-9698930|Reactome:R-HSA-9698933|Reactome:R-HSA-5228406|Reactome:R-HSA-5229111|Reactome:R-HSA-5210943|Reactome:R-HSA-5244428|Reactome:R-HSA-5250884|Reactome:R-HSA-5244404							GO:0015266|GO:0015463		molecular_function											owl:Class	
GO:0005760	biolink:NamedThing	gamma DNA polymerase complex	A DNA polymerase complex consisting of a large subunit, responsible for the catalytic activities, and a small accessory subunit. Functions in the replication and repair of mitochondrial DNA.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0042575	biolink:NamedThing	DNA polymerase complex	A protein complex that possesses DNA polymerase activity and is involved in template directed synthesis of DNA.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0032914	biolink:NamedThing	positive regulation of transforming growth factor beta1 production	Any process that activates or increases the frequency, rate, or extent of production of transforming growth factor-beta1.	tmpzr1t_l9r_go_relaxed.owl	upregulation of transforming growth factor-beta1 production|up regulation of transforming growth factor-beta1 production|positive regulation of TGFB1 production|activation of transforming growth factor-beta1 production|positive regulation of TGF-B1 production|up-regulation of transforming growth factor-beta1 production|stimulation of transforming growth factor-beta1 production													biological_process											owl:Class	
GO:0004726	biolink:NamedThing	non-membrane spanning protein tyrosine phosphatase activity	Catalysis of the reaction: non-membrane spanning protein tyrosine phosphate + H2O = non-membrane spanning protein tyrosine + phosphate.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-177926|Reactome:R-HSA-177935|Reactome:R-HSA-177923|Reactome:R-HSA-177924|Reactome:R-HSA-9635739									molecular_function											owl:Class	
GO:0004725	biolink:NamedThing	protein tyrosine phosphatase activity	Catalysis of the reaction: protein tyrosine phosphate + H2O = protein tyrosine + phosphate.	tmpzr1t_l9r_go_relaxed.owl	PTP-phosphatase activity|[phosphotyrosine]protein phosphatase activity|tyrosylprotein phosphatase activity|phosphotyrosine protein phosphatase activity|phosphotyrosylprotein phosphatase activity|protein phosphotyrosine phosphatase activity|tyrosine O-phosphate phosphatase activity|protein-tyrosine-phosphatase activity|phosphotyrosine phosphatase activity|phosphotyrosine histone phosphatase activity|phosphoprotein phosphatase (phosphotyrosine) activity|PPT-phosphatase activity|PTPase activity|protein-tyrosine-phosphate phosphohydrolase activity				EC:3.1.3.48|Reactome:R-HSA-1549564|Reactome:R-HSA-8864125|Reactome:R-HSA-6807008|Reactome:R-HSA-8855381|Reactome:R-HSA-6807027|MetaCyc:PROTEIN-TYROSINE-PHOSPHATASE-RXN|Reactome:R-HSA-74733|Reactome:R-HSA-74748|Reactome:R-HSA-5683967|Reactome:R-HSA-8867658|Reactome:R-HSA-997314|Reactome:R-HSA-203797|Reactome:R-HSA-9603719|Reactome:R-HSA-1169210|Reactome:R-HSA-202214|Reactome:R-HSA-391868|Reactome:R-HSA-997309|Reactome:R-HSA-8849435|Reactome:R-HSA-9636439|RHEA:10684|Reactome:R-HSA-8863804|Reactome:R-HSA-8867047|Reactome:R-HSA-8852200|Reactome:R-HSA-1169188|Reactome:R-HSA-9698408|Reactome:R-HSA-389758|Reactome:R-HSA-74747|Reactome:R-HSA-914036|Reactome:R-HSA-997311|Reactome:R-HSA-8864036|Reactome:R-HSA-1169192|Reactome:R-HSA-9635461|Reactome:R-HSA-877308|Reactome:R-HSA-997326|Reactome:R-HSA-445089|Reactome:R-HSA-377643|Reactome:R-HSA-8864029|Reactome:R-HSA-8937767									molecular_function											owl:Class	
GO:0090110	biolink:NamedThing	COPII-coated vesicle cargo loading	The formation of a macromolecular complex between the COPII coat proteins and proteins and/or lipoproteins that are going to be transported by the COPII vesicle to the Golgi.	tmpzr1t_l9r_go_relaxed.owl	cargo loading into COPII vesicle|cargo loading into COPII-coated vesicle|cargo selection into COPII-coated vesicle|COPII coat-cargo complex assembly							tb	2009-12-06T08:28:34Z					biological_process											owl:Class	
GO:1903559	biolink:NamedThing	3-cyano-L-alanine catabolic process	The chemical reactions and pathways resulting in the breakdown of 3-cyano-L-alanine.	tmpzr1t_l9r_go_relaxed.owl	3-cyano-L-alanine breakdown|3-cyano-L-alanine degradation|3-cyano-L-alanine catabolism							kmv	2014-10-21T17:13:10Z					biological_process											owl:Class	
GO:0043522	biolink:NamedThing	leucine zipper domain binding	Binding to a leucine zipper domain, a protein secondary structure exhibiting a periodic repetition of leucine residues at every seventh position over a distance covering eight helical turns.	tmpzr1t_l9r_go_relaxed.owl	leucine zipper binding													molecular_function											owl:Class	
GO:0030275	biolink:NamedThing	LRR domain binding	Binding to a LRR domain (leucine rich repeats) of a protein.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1902134	biolink:NamedThing	(+)-secoisolariciresinol catabolic process	The chemical reactions and pathways resulting in the breakdown of (+)-secoisolariciresinol.	tmpzr1t_l9r_go_relaxed.owl	(+)-secoisolariciresinol degradation|(+)-secoisolariciresinol breakdown|(+)-secoisolariciresinol catabolism							ms	2013-05-21T08:50:09Z					biological_process											owl:Class	
GO:0019091	biolink:NamedThing	mitochondrial lrRNA export from mitochondrion	The process in which a lrRNA, large subunit ribosomal ribonucleic acid, is transported from the mitochondrial matrix into the cytosol.	tmpzr1t_l9r_go_relaxed.owl	mitochondrial lrRNA export|mitochondrial lrRNA, mitochondrial export|export of mitochondrial lrRNA|mitochondrial lrRNA transport from mitochondrion|mitochondrial lrRNA export out of mitochondrion|mitochondrial lrRNA export from mitochondria													biological_process											owl:Class	
GO:0019090	biolink:NamedThing	mitochondrial rRNA export from mitochondrion	The process in which a rRNA, ribosomal ribonucleic acid, is transported from the mitochondrial matrix into the cytosol.	tmpzr1t_l9r_go_relaxed.owl	export of mitochondrial rRNA|mitochondrial rRNA export from mitochondria|mitochondrial rRNA, mitochondrial export|mitochondrial rRNA export out of mitochondrion|mitochondrial rRNA transport from mitochondrion|mitochondrial rRNA export													biological_process											owl:Class	
GO:1990569	biolink:NamedThing	UDP-N-acetylglucosamine transmembrane transport	The process in which UDP-N-acetylglucosamine is transported across a membrane.	tmpzr1t_l9r_go_relaxed.owl	UDP-N-acetylglucosamine transport							vw	2014-11-27T11:56:35Z			GO:0015788		biological_process											owl:Class	
GO:0061063	biolink:NamedThing	positive regulation of nematode larval development	Any process that increases the rate, frequency, or extent of nematode larval development, the process whose specific outcome is the progression of the nematode larva over time, from its formation to the mature structure. Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-03-11T01:03:34Z					biological_process											owl:Class	
GO:0060382	biolink:NamedThing	regulation of DNA strand elongation	Any process that modulates the rate, frequency or extent of DNA strand elongation. DNA strand elongation is the DNA metabolic process in which an existing DNA strand is extended by activities including the addition of nucleotides to the 3' end of the strand.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1901273	biolink:NamedThing	2-dehydro-3-deoxy-D-gluconic acid catabolic process	The chemical reactions and pathways resulting in the breakdown of 2-dehydro-3-deoxy-D-gluconic acid.	tmpzr1t_l9r_go_relaxed.owl	2-dehydro-3-deoxy-D-gluconic acid degradation|2-dehydro-3-deoxy-D-gluconic acid catabolism|2-dehydro-3-deoxy-D-gluconic acid breakdown							yaf	2012-08-17T14:46:37Z					biological_process											owl:Class	
GO:0021727	biolink:NamedThing	intermediate reticular formation development	The process whose specific outcome is the progression of the intermediate reticular formation over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl	intermediate reticular nucleus development													biological_process											owl:Class	
GO:0062172	biolink:NamedThing	lutein catabolic process	The chemical reactions and pathways resulting in the breakdown of lutein.	tmpzr1t_l9r_go_relaxed.owl	lutein catabolism|lutein breakdown|lutein degradation							dph	2019-11-18T16:06:07Z					biological_process											owl:Class	
GO:0062170	biolink:NamedThing	lutein metabolic process	The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform lutein.	tmpzr1t_l9r_go_relaxed.owl	lutein metabolism							dph	2019-11-18T15:56:36Z					biological_process											owl:Class	
GO:0102912	biolink:NamedThing	(-)-lactol dehydrogenase activity	Catalysis of the reaction: (-)-lactol + NAD <=> H+ + (-)-matairesinol + NADH.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-8681									molecular_function											owl:Class	
GO:0043336	biolink:NamedThing	site-specific telomere resolvase activity	Catalysis of a site-specific breakage and reunion reaction that generates two hairpin telomeres from a replicated telomere substrate. Occurs via a two-step transesterification with a protein-DNA intermediate similar to that used by topoisomerases and site-specific recombinases.	tmpzr1t_l9r_go_relaxed.owl	TelN|ResT					Note that while this enzyme uses a similar reaction chemistry to topoisomerases and site-specific recombinases, it performs a unique reaction. Topoisomerases promote breakage and reunion of either one or two DNA strands to alter the topological state of a DNA molecule. Site-specific recombinases perform a more complex reaction in which four strands are broken and subsequently joined to a different DNA duplex, resulting in the production of a recombinant product. The telomere resolvases on the other hand, must break two phosphodiester bonds in a single DNA duplex (one on each strand) and join each end with the opposite DNA strand to form covalently closed hairpin telomeres.								molecular_function											owl:Class	
GO:0046337	biolink:NamedThing	phosphatidylethanolamine metabolic process	The chemical reactions and pathways involving phosphatidylethanolamine, any of a class of glycerophospholipids in which a phosphatidyl group is esterified to the hydroxyl group of ethanolamine. It is a major structural phospholipid in mammalian systems. It tends to be more abundant than phosphatidylcholine in the internal membranes of the cell and is an abundant component of prokaryotic membranes.	tmpzr1t_l9r_go_relaxed.owl	phosphatidylethanolamine metabolism													biological_process											owl:Class	
GO:0140081	biolink:NamedThing	glycosylated region protein binding	Binding to a glycosylated region of a protein.	tmpzr1t_l9r_go_relaxed.owl								pg	2017-07-25T10:58:31Z					molecular_function											owl:Class	
GO:0071865	biolink:NamedThing	regulation of apoptotic process in bone marrow cell	Any process that modulates the occurrence or rate of cell death by apoptotic process in the bone marrow.	tmpzr1t_l9r_go_relaxed.owl	regulation of apoptotic process in bone marrow|regulation of apoptosis in bone marrow							mah	2010-09-13T02:16:43Z					biological_process											owl:Class	
GO:0033714	biolink:NamedThing	secondary-alcohol oxidase activity	Catalysis of the reaction: O(2) + secondary alcohol = H(2)O(2) + ketone.	tmpzr1t_l9r_go_relaxed.owl	polyvinyl alcohol oxidase activity|secondary alcohol oxidase activity|secondary-alcohol:oxygen oxidoreductase activity				MetaCyc:SECONDARY-ALCOHOL-OXIDASE-RXN|KEGG_REACTION:R02277|RHEA:23180|EC:1.1.3.18									molecular_function											owl:Class	
GO:1990710	biolink:NamedThing	MutS complex	A homodimeric mismatch repair complex involved in binding to and correcting insertion/deletion mutations.	tmpzr1t_l9r_go_relaxed.owl	MutS mismatch repair complex					An example of this is MutS in E. coli (UniProt symbol P23909) in PMID:21666597 (inferred from physical interaction).		bhm	2015-03-25T11:42:56Z					cellular_component											owl:Class	
GO:0033090	biolink:NamedThing	positive regulation of extrathymic T cell differentiation	Any process that activates or increases the frequency, rate or extent of extrathymic T cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of extrathymic T cell development					Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.								biological_process											owl:Class	
GO:0033082	biolink:NamedThing	regulation of extrathymic T cell differentiation	Any process that modulates the frequency, rate or extent of extrathymic T cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	regulation of extrathymic T cell development					Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.								biological_process											owl:Class	
GO:0050850	biolink:NamedThing	positive regulation of calcium-mediated signaling	Any process that activates or increases the frequency, rate or extent of calcium-mediated signaling.	tmpzr1t_l9r_go_relaxed.owl	up regulation of calcium-mediated signaling|positive regulation of calcium-mediated signalling|up-regulation of calcium-mediated signaling|upregulation of calcium-mediated signaling|stimulation of calcium-mediated signaling|activation of calcium-mediated signaling													biological_process											owl:Class	
GO:2000876	biolink:NamedThing	positive regulation of glyoxylate cycle	Any process that activates or increases the frequency, rate or extent of glyoxylate cycle.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of glyoxylate bypass							bf	2011-07-27T01:27:18Z					biological_process											owl:Class	
GO:1990930	biolink:NamedThing	mRNA N1-methyladenosine dioxygenase activity	Catalysis of the oxidative demethylation of N1-methyladenosine RNA, with concomitant decarboxylation of 2-oxoglutarate and releases oxidized methyl group on N1-methyladenosine as formaldehyde.	tmpzr1t_l9r_go_relaxed.owl	RNA N1-methyladenosine dioxygenase activity|RNA N(1)-methyladenosine dioxygenase activity	https://github.com/geneontology/go-ontology/issues/21812			EC:1.14.11.54|RHEA:49516			sp	2016-03-10T08:06:47Z					molecular_function											owl:Class	
GO:0031360	biolink:NamedThing	intrinsic component of thylakoid membrane	The component of the thylakoid membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.	tmpzr1t_l9r_go_relaxed.owl	intrinsic to thylakoid membrane													cellular_component											owl:Class	
GO:0047307	biolink:NamedThing	diaminobutyrate-pyruvate transaminase activity	Catalysis of the reaction: L-2,4-diaminobutyrate + pyruvate = L-alanine + L-aspartate 4-semialdehyde.	tmpzr1t_l9r_go_relaxed.owl	L-diaminobutyric acid transaminase activity|diaminobutyrate-pyruvate aminotransferase activity|diaminobutyrate--pyruvate aminotransferase activity|L-2,4-diaminobutanoate:pyruvate aminotransferase activity				EC:2.6.1.46|MetaCyc:2.6.1.46-RXN|RHEA:12380|KEGG_REACTION:R02293									molecular_function											owl:Class	
GO:0090463	biolink:NamedThing	lysine homeostasis	Any process involved in the maintenance of an internal steady state of lysine within an organism or cell.	tmpzr1t_l9r_go_relaxed.owl								tb	2012-09-24T14:22:02Z					biological_process											owl:Class	
GO:0080144	biolink:NamedThing	amino acid homeostasis	Any process involved in the maintenance of an internal steady state of amino acid within an organism or cell.	tmpzr1t_l9r_go_relaxed.owl								dhl	2010-01-27T04:47:27Z					biological_process											owl:Class	
GO:0018316	biolink:NamedThing	peptide cross-linking via L-cystine	The oxidation of two peptidyl-cysteine residues to form a peptidyl-L-cystine (dicysteine) in which segments of peptide chain are linked by a disulfide bond; the cross-link may be between different or the same peptide chain.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0025									biological_process											owl:Class	
GO:1903386	biolink:NamedThing	negative regulation of homophilic cell adhesion	Any process that stops, prevents or reduces the frequency, rate or extent of homophilic cell adhesion.	tmpzr1t_l9r_go_relaxed.owl	downregulation of homophilic cell adhesion|down-regulation of homophilic cell adhesion|inhibition of homophilic cell adhesion|down regulation of homophilic cell adhesion							als	2014-08-27T09:57:38Z					biological_process											owl:Class	
GO:0031080	biolink:NamedThing	nuclear pore outer ring	A subcomplex of the nuclear pore complex (NPC) that forms the outer rings of the core scaffold, a lattice-like structure that gives the NPC its shape and strength. In S. cerevisiae, the two outer rings each contain multiple copies of the following proteins: Nup133p, Nup120p, Nup145Cp, Nup85p, Nup84p, Seh1p, and Sec13p. In vertebrates, the two outer rings each contain multiple copies of the following proteins: Nup133, Nup160, Nup96, Nup75, Nup107, Seh1, Sec13, Nup43, Nup37, and ALADIN. Components are arranged in 8-fold symmetrical 'spokes' around the central transport channel. A single 'spoke', can be isolated and is sometimes referred to as the Nup84 complex (S. cerevisiae) or the Nup107-160 complex (vertebrates).	tmpzr1t_l9r_go_relaxed.owl	Nup84 complex|Nup107-120 complex|Nup107-160 complex													cellular_component											owl:Class	
GO:0009337	biolink:NamedThing	sulfite reductase complex (NADPH)	A multisubunit iron flavoprotein, which in yeast is composed of 2 alpha and 2 beta subunits. Catalyzes the reduction of sulfite to sulfide.	tmpzr1t_l9r_go_relaxed.owl	sulphite reductase complex (NADPH)					See also the molecular function term 'sulfite reductase (NADPH) activity ; GO:0004783'.								cellular_component											owl:Class	
GO:0019620	biolink:NamedThing	aerobic benzoate metabolic process	The chemical reactions and pathways involving benzoate, the anion of benzoic acid (benzenecarboxylic acid) that occur in the presence of oxygen.	tmpzr1t_l9r_go_relaxed.owl	aerobic benzoate metabolism													biological_process											owl:Class	
GO:0018874	biolink:NamedThing	benzoate metabolic process	The chemical reactions and pathways involving benzoate, the anion of benzoic acid (benzenecarboxylic acid), a fungistatic compound widely used as a food preservative; it is conjugated to glycine in the liver and excreted as hippuric acid.	tmpzr1t_l9r_go_relaxed.owl	benzoate metabolism				UM-BBD_pathwayID:benz2|MetaCyc:P321-PWY									biological_process											owl:Class	
GO:1900214	biolink:NamedThing	regulation of apoptotic process involved in metanephric collecting duct development	Any process that modulates the frequency, rate or extent of apoptotic process involved in metanephric collecting duct development.	tmpzr1t_l9r_go_relaxed.owl	regulation of apoptotic program of metanephric collecting duct development|regulation of apoptotic cell death of metanephric collecting duct development|regulation of apoptotic process of metanephric collecting duct development|regulation of signaling (initiator) caspase activity of metanephric collecting duct development|regulation of type I programmed cell death of metanephric collecting duct development|regulation of apoptotic programmed cell death of metanephric collecting duct development|regulation of programmed cell death by apoptosis of metanephric collecting duct development|regulation of apoptosis of metanephric collecting duct development							yaf	2012-03-22T10:53:21Z					biological_process											owl:Class	
GO:1904371	biolink:NamedThing	negative regulation of protein localization to actin cortical patch	Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to actin cortical patch.	tmpzr1t_l9r_go_relaxed.owl	downregulation of protein localisation to actin cortical patch|down-regulation of protein localisation to actin cortical patch|inhibition of protein localisation to actin cortical patch|down regulation of protein localization to actin cortical patch|down-regulation of protein localization to actin cortical patch|inhibition of protein localization to actin cortical patch|negative regulation of protein localisation to actin cortical patch|downregulation of protein localization to actin cortical patch|down regulation of protein localisation to actin cortical patch							sl	2015-06-18T22:23:37Z					biological_process											owl:Class	
GO:1904777	biolink:NamedThing	negative regulation of protein localization to cell cortex	Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cell cortex.	tmpzr1t_l9r_go_relaxed.owl	inhibition of protein localisation to cell cortex|downregulation of protein localization to cell cortex|down-regulation of protein localization to cell cortex|down regulation of protein localisation to cell cortex|downregulation of protein localisation to cell cortex|inhibition of protein localization to cell cortex|down-regulation of protein localisation to cell cortex|negative regulation of protein localisation to cell cortex|down regulation of protein localization to cell cortex					An example is cye-1 in C. elegans, UniProt ID O01501 in PMID:17115027.		es	2015-10-29T16:55:08Z					biological_process											owl:Class	
GO:0047711	biolink:NamedThing	blasticidin-S deaminase activity	Catalysis of the reaction: blasticidin S + H2O = deaminohydroxyblasticidin S + NH3.	tmpzr1t_l9r_go_relaxed.owl	blasticidin-S aminohydrolase activity				RHEA:10148|MetaCyc:BLASTICIDIN-S-DEAMINASE-RXN|EC:3.5.4.23									molecular_function											owl:Class	
GO:0015187	biolink:NamedThing	glycine transmembrane transporter activity	Enables the transfer of glycine from one side of a membrane to the other. Glycine is aminoethanoic acid.	tmpzr1t_l9r_go_relaxed.owl	glycine transporter activity|glycine betaine/proline porter activity|proline/glycine/betaine:hydrogen/sodium symporter activity													molecular_function											owl:Class	
GO:0051769	biolink:NamedThing	regulation of nitric-oxide synthase biosynthetic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of a nitric-oxide synthase enzyme.	tmpzr1t_l9r_go_relaxed.owl	regulation of nitric-oxide synthase (type 2) biosynthesis|regulation of NO synthase biosynthesis|regulation of nitric-oxide synthase (type II) biosynthetic process|regulation of NOS biosynthesis|regulation of NO synthase biosynthetic process|regulation of nitric-oxide synthase (type II) biosynthesis|regulation of NOS2 synthase biosynthesis|regulation of NOS biosynthetic process|regulation of nitric-oxide synthase (type 2) biosynthetic process|regulation of nitric-oxide synthase 2 biosynthetic process|regulation of NOS2 synthase biosynthetic process											GO:0051772		biological_process											owl:Class	
GO:0010556	biolink:NamedThing	regulation of macromolecule biosynthetic process	Any process that modulates the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0097466	biolink:NamedThing	ubiquitin-dependent glycoprotein ERAD pathway	An ERAD pathway whereby endoplasmic reticulum (ER)-resident glycoproteins are targeted for degradation. Includes differential processing of the glycoprotein sugar chains, retrotranslocation to the cytosol and degradation by the ubiquitin-proteasome pathway. A glycoprotein is a compound in which a carbohydrate component is covalently bound to a protein component.	tmpzr1t_l9r_go_relaxed.owl	glycoprotein ERAD|ER-associated glycoprotein degradation|misfolded or incompletely synthesized glycoprotein catabolic process|gpERAD							pr	2013-02-05T16:37:13Z					biological_process											owl:Class	
GO:0006516	biolink:NamedThing	glycoprotein catabolic process	The chemical reactions and pathways resulting in the breakdown of a glycoprotein, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide.	tmpzr1t_l9r_go_relaxed.owl	glycoprotein degradation|glycoprotein catabolism|glycoprotein breakdown													biological_process											owl:Class	
GO:1904890	biolink:NamedThing	negative regulation of excitatory synapse assembly	Any process that stops, prevents or reduces the frequency, rate or extent of excitatory synapse assembly.	tmpzr1t_l9r_go_relaxed.owl	downregulation of excitatory synapse assembly|inhibition of excitatory synapse assembly|negative regulation of excitatory synapse formation|down regulation of excitatory synapse assembly|inhibition of excitatory synapse formation|down regulation of excitatory synapse formation|down-regulation of excitatory synapse assembly|down-regulation of excitatory synapse formation|downregulation of excitatory synapse formation							bf	2016-01-07T14:36:00Z					biological_process											owl:Class	
GO:1904578	biolink:NamedThing	response to thapsigargin	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a thapsigargin stimulus.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-08-19T18:06:22Z					biological_process											owl:Class	
GO:0018681	biolink:NamedThing	deisopropylatrazine monooxygenase activity	Catalysis of the reaction: 2 deisopropylatrazine + O2 = 2 acetaldehyde + 2 deisopropyldeethylatrazine.	tmpzr1t_l9r_go_relaxed.owl					KEGG_REACTION:R05567|EC:1.14.15.-									molecular_function											owl:Class	
GO:0099028	biolink:NamedThing	anchored component of postynaptic endocytic zone membrane	The component of the postynaptic endocytic zone membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0030865	biolink:NamedThing	cortical cytoskeleton organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures in the cell cortex, i.e. just beneath the plasma membrane.	tmpzr1t_l9r_go_relaxed.owl	cortical cytoskeleton organisation|cortical cytoskeleton organization and biogenesis													biological_process											owl:Class	
GO:0090144	biolink:NamedThing	mitochondrial nucleoid organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the mitochondrial nucleoid. The mitochondrial nucleoid is the region of a mitochondrion to which the DNA is confined.	tmpzr1t_l9r_go_relaxed.owl	mitochondrial nucleoid organisation							tb	2009-12-08T02:38:26Z					biological_process											owl:Class	
GO:0090143	biolink:NamedThing	nucleoid organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nucleoid. The nucleoid is the region of a bacterial cell, virion, mitochondrion or chloroplast to which the DNA is confined.	tmpzr1t_l9r_go_relaxed.owl	nucleoid organisation							tb	2009-12-08T02:35:48Z					biological_process											owl:Class	
GO:0034772	biolink:NamedThing	histone H4-K20 dimethylation	The modification of histone H4 by addition of two methyl groups to lysine at position 20 of the histone.	tmpzr1t_l9r_go_relaxed.owl	histone lysine H4 K20 dimethylation|histone H4 K20 dimethylation													biological_process											owl:Class	
GO:0018027	biolink:NamedThing	peptidyl-lysine dimethylation	The methylation of peptidyl-lysine to form peptidyl-N6,N6-dimethyl-L-lysine.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0075									biological_process											owl:Class	
GO:0046073	biolink:NamedThing	dTMP metabolic process	The chemical reactions and pathways involving dTMP, deoxyribosylthymine monophosphate (2'-deoxyribosylthymine 5'-phosphate).	tmpzr1t_l9r_go_relaxed.owl	dTMP metabolism													biological_process											owl:Class	
GO:0043586	biolink:NamedThing	tongue development	The process whose specific outcome is the progression of the tongue over time, from its formation to the mature structure. The tongue is the movable, muscular organ on the floor of the mouth of most vertebrates, in many other mammals is the principal organ of taste, aids in the prehension of food, in swallowing, and in modifying the voice as in speech.	tmpzr1t_l9r_go_relaxed.owl	lingua development|glossa development													biological_process											owl:Class	
GO:0015494	biolink:NamedThing	aromatic amino acid:proton symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: aromatic amino acid(out) + H+(out) = aromatic amino acid(in) + H+(in).	tmpzr1t_l9r_go_relaxed.owl	aromatic amino acid:hydrogen symporter activity													molecular_function											owl:Class	
GO:0017134	biolink:NamedThing	fibroblast growth factor binding	Binding to a fibroblast growth factor.	tmpzr1t_l9r_go_relaxed.owl	FGF 1 binding|FGF 4 binding|FGF binding|fibroblast growth factor 5 binding|fibroblast growth factor 6 binding|fibroblast growth factor 4 binding|fibroblast growth factor 2 binding|FGF 6 binding|fibroblast growth factor 1 binding|FGF 3 binding|fibroblast growth factor 3 binding|FGF 2 binding|FGF 5 binding											GO:0048602|GO:0048606|GO:0048603|GO:0048607|GO:0048605|GO:0048604		molecular_function											owl:Class	
GO:0051632	biolink:NamedThing	negative regulation of acetylcholine uptake	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of acetylcholine into a cell.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of acetylcholine uptake|down regulation of acetylcholine uptake|downregulation of acetylcholine uptake|negative regulation of acetylcholine import													biological_process											owl:Class	
GO:2000416	biolink:NamedThing	regulation of eosinophil migration	Any process that modulates the frequency, rate or extent of eosinophil migration.	tmpzr1t_l9r_go_relaxed.owl								mah	2011-02-23T01:43:23Z					biological_process											owl:Class	
GO:0046367	biolink:NamedThing	allose catabolic process	The chemical reactions and pathways resulting in the breakdown of allose, allo-hexose, an aldohexose similar to glucose, differing only in the configuration of the hydroxyl group of C-3.	tmpzr1t_l9r_go_relaxed.owl	allose breakdown|allose degradation|allose catabolism													biological_process											owl:Class	
GO:0019313	biolink:NamedThing	allose metabolic process	The chemical reactions and pathways involving allose, allo-hexose, an aldohexose similar to glucose, differing only in the configuration of the hydroxyl group of C-3.	tmpzr1t_l9r_go_relaxed.owl	allose metabolism													biological_process											owl:Class	
GO:0106158	biolink:NamedThing	glycero-3-phosphocholine acyltransferase activity	Catalysis of the reaction:acyl-CoA + glycerophosphocholine = CoA + 1-acyl-sn-glycero-3-phosphocholine.	tmpzr1t_l9r_go_relaxed.owl	glycerophosphocholine O-acyltransferase activity|GPACT activity	https://github.com/geneontology/go-ontology/issues/16665			RHEA:58476			hjd	2018-11-26T21:21:03Z					molecular_function											owl:Class	
GO:0090031	biolink:NamedThing	positive regulation of steroid hormone biosynthetic process	Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroid hormones,compounds with a 1, 2, cyclopentanoperhydrophenanthrene nucleus that act as hormones.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-08-03T10:40:32Z					biological_process											owl:Class	
GO:0032206	biolink:NamedThing	positive regulation of telomere maintenance	Any process that activates or increases the frequency, rate or extent of a process that affects and monitors the activity of telomeric proteins and the length of telomeric DNA.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of telomere maintenance|up regulation of telomere maintenance|stimulation of telomere maintenance|activation of telomere maintenance|upregulation of telomere maintenance													biological_process											owl:Class	
GO:0010635	biolink:NamedThing	regulation of mitochondrial fusion	Any process that modulates the frequency, rate or extent of merging of two or more mitochondria within a cell to form a single compartment.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0043299	biolink:NamedThing	leukocyte degranulation	The regulated exocytosis of secretory granules by a leukocyte.	tmpzr1t_l9r_go_relaxed.owl	leucocyte degranulation|immune cell degranulation|leukocyte granule exocytosis|immune cell granule exocytosis													biological_process											owl:Class	
GO:0004605	biolink:NamedThing	phosphatidate cytidylyltransferase activity	Catalysis of the reaction: CTP + phosphatidate = diphosphate + CDP-diacylglycerol.	tmpzr1t_l9r_go_relaxed.owl	CTP:phosphatidate cytidylyltransferase activity|CDP-diacylglyceride synthetase activity|CTP-diacylglycerol synthetase activity|phosphatidate cytidyltransferase activity|CTP:1,2-diacylglycerophosphate-cytidyl transferase activity|phosphatidic acid cytidylyltransferase activity|CDP-diglyceride pyrophosphorylase activity|cytidine diphosphoglyceride pyrophosphorylase activity|CDP-diglyceride synthetase activity|CDP-DG|CDP-diglyceride synthase activity|CDP-diglyceride diphosphorylase activity|DAG synthetase activity|CDP diglyceride pyrophosphorylase activity|CDP-diacylglycerol synthase activity				MetaCyc:CDPDIGLYSYN-RXN|Reactome:R-HSA-1483121|RHEA:16229|Reactome:R-HSA-1483165|EC:2.7.7.41									molecular_function											owl:Class	
GO:0072271	biolink:NamedThing	metanephric short descending thin limb development	The process whose specific outcome is the progression of the metanephric short descending thin limb over time, from its formation to the mature structure. The metanephric short descending thin limb is the descending thin limb of a short nephron in the metanephros that has a squamous epithelial morphology.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-03-30T03:16:25Z					biological_process											owl:Class	
GO:0072063	biolink:NamedThing	short descending thin limb development	The process whose specific outcome is the progression of the short descending thin limb over time, from its formation to the mature structure. The short descending thin limb is the descending thin limb of a short nephron that has a squamous epithelial morphology.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-01-25T04:12:39Z					biological_process											owl:Class	
GO:0007526	biolink:NamedThing	larval somatic muscle development	The process whose specific outcome is the progression of the larval somatic muscle over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0007525	biolink:NamedThing	somatic muscle development	The process whose specific outcome is the progression of the somatic muscle over time, from its formation to the mature structure. Somatic muscles are striated muscle structures that connect to the exoskeleton or cuticle.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0010820	biolink:NamedThing	positive regulation of T cell chemotaxis	Any process that increases the rate, frequency or extent of T cell chemotaxis. T cell chemotaxis is the directed movement of a T cell in response to an external stimulus.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1900861	biolink:NamedThing	regulation of cordyol C biosynthetic process	Any process that modulates the frequency, rate or extent of cordyol C biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl								di	2012-06-07T01:56:16Z					biological_process											owl:Class	
GO:0070387	biolink:NamedThing	procollagen-proline 4-dioxygenase complex, alpha(II) type	A procollagen-proline 4-dioxygenase complex that contains alpha subunits of the type II isoform; its activity is inhibited by poly(L-proline) only at high concentrations.	tmpzr1t_l9r_go_relaxed.owl	procollagen-proline, 2-oxoglutarate-4-dioxygenase complex, alpha(II) type|prolyl 4-hydroxylase complex (alpha(II)-type)													cellular_component											owl:Class	
GO:0016222	biolink:NamedThing	procollagen-proline 4-dioxygenase complex	A protein complex that catalyzes the formation of procollagen trans-4-hydroxy-L-proline and succinate from procollagen L-proline and 2-oxoglutarate, requiring Fe2+ and ascorbate. Contains two alpha subunits that contribute to most parts of the catalytic sites, and two beta subunits that are identical to protein-disulfide isomerase.	tmpzr1t_l9r_go_relaxed.owl	procollagen-proline, 2-oxoglutarate-4-dioxygenase complex|prolyl 4-hydroxylase complex													cellular_component											owl:Class	
GO:0031553	biolink:NamedThing	positive regulation of brain-derived neurotrophic factor-activated receptor activity	Any process that activates or increases the frequency, rate or extent of brain-derived neurotrophic factor-activated receptor activity.	tmpzr1t_l9r_go_relaxed.owl	up regulation of brain-derived neurotrophic factor receptor activity|positive regulation of BDNF receptor activity|upregulation of brain-derived neurotrophic factor receptor activity|stimulation of brain-derived neurotrophic factor receptor activity|positive regulation of brain-derived neurotrophic factor receptor activity|activation of brain-derived neurotrophic factor receptor activity|up-regulation of brain-derived neurotrophic factor receptor activity													biological_process											owl:Class	
GO:0039013	biolink:NamedThing	pronephric distal tubule morphogenesis	The process in which the anatomical structures of a pronephric nephron distal tubule are generated and organized. A pronephric nephron tubule is an epithelial tube that is part of the pronephros.	tmpzr1t_l9r_go_relaxed.owl								bf	2010-07-02T09:58:03Z					biological_process											owl:Class	
GO:0039008	biolink:NamedThing	pronephric nephron tubule morphogenesis	The process in which the anatomical structures of a pronephric nephron tubule are generated and organized from an epithelium. A pronephric nephron tubule is an epithelial tube that is part of the pronephric nephron.	tmpzr1t_l9r_go_relaxed.owl								bf	2010-07-02T09:45:55Z					biological_process											owl:Class	
GO:0000213	biolink:NamedThing	tRNA-intron endonuclease activity	Catalysis of the endonucleolytic cleavage of pre-tRNA, producing 5'-hydroxyl and 2',3'-cyclic phosphate termini, and specifically removing the intron.	tmpzr1t_l9r_go_relaxed.owl	transfer ribonucleate intron endoribonuclease activity|transfer splicing endonuclease activity|tRNATRPintron endonuclease activity|tRNA-splicing endonuclease activity|splicing endonuclease activity|tRNA splicing endonuclease activity|tRNA-intron endoribonuclease activity				EC:3.1.27.9|MetaCyc:3.1.27.9-RXN									molecular_function											owl:Class	
GO:0080175	biolink:NamedThing	phragmoplast microtubule organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of structures formed of microtubules and associated proteins in phragmoplast, a plant cell specific structure that forms during late cytokinesis. Phragmoplast serves as a scaffold for cell plate assembly and subsequent formation of a new cell wall separating the two daughter cells.	tmpzr1t_l9r_go_relaxed.owl	phragmoplast microtubule organisation|phragmoplast microtubule cytoskeleton organization							dhl	2011-04-28T03:54:11Z					biological_process											owl:Class	
GO:0045988	biolink:NamedThing	negative regulation of striated muscle contraction	Any process that stops, prevents, or reduces the frequency, rate or extent of striated muscle contraction.	tmpzr1t_l9r_go_relaxed.owl	inhibition of striated muscle contraction|downregulation of striated muscle contraction|down regulation of striated muscle contraction|down-regulation of striated muscle contraction													biological_process											owl:Class	
GO:0006942	biolink:NamedThing	regulation of striated muscle contraction	Any process that modulates the frequency, rate or extent of striated muscle contraction.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0070774	biolink:NamedThing	phytoceramidase activity	Catalysis of the reaction: a phytoceramide + H2O = a fatty acid + phytosphingosine.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-428262|KEGG_REACTION:R06528|MetaCyc:CERAMIDASE-YEAST-RXN			mah	2009-07-02T10:52:42Z					molecular_function											owl:Class	
GO:0035191	biolink:NamedThing	nuclear axial expansion	The stepwise asymmetric spreading out of nuclei internally along the anterior-posterior axis of the developing insect embryo during mitotic cycles 4 to 6. This movement leads to the distribution of nuclei in a hollow ellipsoid underlying the cortex.	tmpzr1t_l9r_go_relaxed.owl	nuclear distribution along anterior-posterior axis|nucleus distribution along anterior-posterior axis													biological_process											owl:Class	
GO:0035190	biolink:NamedThing	syncytial nuclear migration	The directed movement of nuclei within the syncytial embryo of insects. These precise temporal and spatial patterns of nuclear movement are coordinated with mitotic divisons and are required during blastoderm formation to reposition dividing nuclei from the interior of the syncytial embryo to the cortex.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0048302	biolink:NamedThing	regulation of isotype switching to IgG isotypes	Any process that modulates the frequency, rate or extent of isotype switching to IgG isotypes.	tmpzr1t_l9r_go_relaxed.owl	regulation of class switching to IgG isotypes|regulation of class switch recombination to IgG isotypes|regulation of isotype switch recombination to IgG isotypes													biological_process											owl:Class	
GO:0000337	biolink:NamedThing	regulation of transposition, DNA-mediated	Any process that modulates the frequency, rate or extent of DNA transposition, the process of transposing (moving to a different location) a segment of a chromosome or a piece of a DNA molecule.	tmpzr1t_l9r_go_relaxed.owl	regulation of DNA transposition													biological_process											owl:Class	
GO:0010044	biolink:NamedThing	response to aluminum ion	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an aluminum ion stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to aluminum|response to aluminium ion													biological_process											owl:Class	
GO:0140280	biolink:NamedThing	negative regulation of mitotic division septum assembly	Any process that stops, prevents or reduces the frequency, rate or extent of mitotic division septum formation. Division septum formation is the assembly and arrangement of a septum that spans the plasma membrane interface between progeny cells following cytokinesis.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of septin assembly and septum formation involved in mitotic cell cycle|downregulation of division septum formation involved in mitotic cell cycle|negative regulation of septin assembly and septum biosynthesis involved in mitotic cell cycle|down-regulation of division septum formation involved in mitotic cell cycle|negative regulation of division septum formation involved in mitotic cell cycle|down regulation of division septum formation involved in mitotic cell cycle|negative regulation of formation of division septum involved in mitotic cell cycle|down-regulation of septin assembly and septum biosynthesis involved in mitotic cell cycle|downregulation of formation of division septum involved in mitotic cell cycle|inhibition of mitotic division septum assembly|down-regulation of mitotic division septum assembly|inhibition of septin assembly and septum biosynthesis involved in mitotic cell cycle|down-regulation of formation of division septum involved in mitotic cell cycle|inhibition of division septum formation involved in mitotic cell cycle|negative regulation of septin assembly and septum formation involved in mitotic cell cycle|inhibition of septin assembly and septum formation involved in mitotic cell cycle|downregulation of mitotic division septum assembly|down regulation of mitotic division septum assembly|down regulation of septin assembly and septum formation involved in mitotic cell cycle|inhibition of formation of division septum involved in mitotic cell cycle|down regulation of septin assembly and septum biosynthesis involved in mitotic cell cycle|down regulation of formation of division septum involved in mitotic cell cycle|downregulation of septin assembly and septum formation involved in mitotic cell cycle|downregulation of septin assembly and septum biosynthesis involved in mitotic cell cycle							pg	2018-10-08T10:03:22Z					biological_process											owl:Class	
GO:0002675	biolink:NamedThing	positive regulation of acute inflammatory response	Any process that activates or increases the frequency, rate, or extent of an acute inflammatory response.	tmpzr1t_l9r_go_relaxed.owl	activation of acute inflammatory response|up regulation of acute inflammatory response|stimulation of acute inflammatory response|up-regulation of acute inflammatory response|upregulation of acute inflammatory response													biological_process											owl:Class	
GO:0001998	biolink:NamedThing	angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure	The decrease in blood vessel diameter as a result of the release of angiotensin into the blood stream.	tmpzr1t_l9r_go_relaxed.owl	angiotensin mediated vasoconstriction during control of blood pressure|angiotensin mediated vasoconstriction during blood pressure control|angiotensin mediated vasoconstriction during blood pressure regulation|angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure													biological_process											owl:Class	
GO:0110043	biolink:NamedThing	positive regulation of pharynx morphogenesis	Any process that activates or increases the frequency, rate or extent of pharynx morphogenesis.	tmpzr1t_l9r_go_relaxed.owl								kmv	2017-07-24T21:09:48Z					biological_process											owl:Class	
GO:0110041	biolink:NamedThing	regulation of pharynx morphogenesis	Any process that modulates the frequency, rate or extent of pharynx morphogenesis, the process in which the anatomical structure of the pharynx is generated and organized.	tmpzr1t_l9r_go_relaxed.owl								kmv	2017-07-24T21:00:20Z					biological_process											owl:Class	
GO:0009547	biolink:NamedThing	plastid ribosome	A ribosome contained within a plastid.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0000313	biolink:NamedThing	organellar ribosome	A ribosome contained within a subcellular membrane-bounded organelle.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0102096	biolink:NamedThing	decaprenyl-N-acetyl-alpha-D-glucosaminyl-pyrophosphate:dTDP-alpha-L-rhamnose rhamnosyltransferase activity	Catalysis of the reaction: dTDP-6-deoxy-beta-L-mannose + N-acetyl-alpha-D-glucosaminyl-diphospho-trans,octacis-decaprenol <=> dTDP(3-) + alpha-L-Rhap-(1->3)-alpha-D-GlcpNAc-1-diphospho-trans,octacis-decaprenol + H+.	tmpzr1t_l9r_go_relaxed.owl					EC:2.4.1.289|RHEA:34487|MetaCyc:RXN-11070									molecular_function											owl:Class	
GO:0039621	biolink:NamedThing	T=13 icosahedral viral capsid	The protein coat that surrounds the infective nucleic acid in some virus particles where the subunits (capsomeres) are arranged to form an icosahedron with T=13 symmetry. The T=13 capsid is composed of 12 pentameric and 120 hexameric capsomeres.	tmpzr1t_l9r_go_relaxed.owl					VZ:260			bf	2012-07-18T02:18:59Z					cellular_component											owl:Class	
GO:0098045	biolink:NamedThing	virus baseplate assembly	The aggregation, arrangement and bonding together of a set of components to form a virus baseplate.	tmpzr1t_l9r_go_relaxed.owl								bm	2012-07-25T14:50:32Z					biological_process											owl:Class	
GO:2000590	biolink:NamedThing	negative regulation of metanephric mesenchymal cell migration	Any process that stops, prevents or reduces the frequency, rate or extent of metanephric mesenchymal cell migration.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of metanephric mesenchyme chemotaxis							bf	2011-04-07T03:29:49Z					biological_process											owl:Class	
GO:1905417	biolink:NamedThing	negative regulation of amoeboid sperm motility	Any process that stops, prevents or reduces the frequency, rate or extent of amoeboid sperm motility.	tmpzr1t_l9r_go_relaxed.owl	down regulation of ameboid sperm motility|inhibition of ameboid sperm movement|down-regulation of amoeboid sperm movement|negative regulation of ameboid sperm motility|negative regulation of ameboid sperm movement|inhibition of amoeboid sperm movement|inhibition of amoeboid sperm motility|negative regulation of amoeboid sperm movement|downregulation of amoeboid sperm motility|down regulation of ameboid sperm movement|downregulation of amoeboid sperm movement|inhibition of ameboid sperm motility|down regulation of amoeboid sperm motility|down-regulation of ameboid sperm motility|down-regulation of amoeboid sperm motility|downregulation of ameboid sperm movement|downregulation of ameboid sperm motility|down regulation of amoeboid sperm movement|down-regulation of ameboid sperm movement							pr	2016-09-01T11:28:55Z					biological_process											owl:Class	
GO:2000146	biolink:NamedThing	negative regulation of cell motility	Any process that stops, prevents, or reduces the frequency, rate or extent of cell motility.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of cell locomotion|negative regulation of cell movement|negative regulation of movement of a cell							mah	2010-10-01T09:41:26Z					biological_process											owl:Class	
GO:1990458	biolink:NamedThing	lipooligosaccharide binding	Binding to lipooligosaccharide. Lipooligosaccharides (LOSs) are the major glycolipids expressed on mucosal Gram-negative bacteria.	tmpzr1t_l9r_go_relaxed.owl	endotoxin binding|LOS binding					ChEBI distinguishes an oligosaccharide from a polysaccharide as the latter being anything of length 10 or greater.		hjd	2014-08-15T19:58:08Z					molecular_function											owl:Class	
GO:0061315	biolink:NamedThing	canonical Wnt signaling pathway involved in positive regulation of cardiac muscle cell proliferation	The canonical Wnt signaling pathway that contributes to an expansion of the population of cardiac muscle cells.	tmpzr1t_l9r_go_relaxed.owl	canonical Wnt-activated signaling pathway involved in positive regulation of cardiac muscle cell proliferation|canonical Wnt receptor signalling pathway involved in positive regulation of cardiac muscle cell proliferation|canonical Wnt receptor signaling pathway involved in positive regulation of cardiac muscle cell proliferation							dph	2010-09-24T08:53:58Z					biological_process											owl:Class	
GO:1902874	biolink:NamedThing	positive regulation of horizontal cell localization	Any process that activates or increases the frequency, rate or extent of horizontal cell localization.	tmpzr1t_l9r_go_relaxed.owl	upregulation of horizontal cell localization|positive regulation of horizontal cell positioning|up-regulation of horizontal cell localization|positive regulation of retinal horizontal cell positioning|upregulation of horizontal cell localisation|upregulation of laminar positioning of retinal horizontal cell|upregulation of horizontal cell positioning|activation of laminar positioning of retinal horizontal cell|activation of horizontal cell positioning|up-regulation of laminar positioning of retinal horizontal cell|up regulation of horizontal cell localisation|up-regulation of retinal horizontal cell positioning|activation of horizontal cell localisation|up-regulation of horizontal cell localisation|positive regulation of laminar positioning of retinal horizontal cell|activation of retinal horizontal cell positioning|up regulation of laminar positioning of retinal horizontal cell|up regulation of horizontal cell localization|up regulation of retinal horizontal cell positioning|up regulation of horizontal cell positioning|positive regulation of horizontal cell localisation|up-regulation of horizontal cell positioning|upregulation of retinal horizontal cell positioning|activation of horizontal cell localization							mr	2014-04-03T15:25:09Z					biological_process											owl:Class	
GO:1902872	biolink:NamedThing	regulation of horizontal cell localization	Any process that modulates the frequency, rate or extent of horizontal cell localization.	tmpzr1t_l9r_go_relaxed.owl	regulation of horizontal cell localisation|regulation of retinal horizontal cell positioning|regulation of laminar positioning of retinal horizontal cell|regulation of horizontal cell positioning							mr	2014-04-03T15:24:58Z					biological_process											owl:Class	
GO:1902173	biolink:NamedThing	negative regulation of keratinocyte apoptotic process	Any process that stops, prevents or reduces the frequency, rate or extent of keratinocyte apoptotic process.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of keratinocyte apoptosis|down regulation of keratinocyte apoptotic process|downregulation of keratinocyte apoptotic process|down regulation of keratinocyte apoptosis|negative regulation of keratinocyte apoptosis|inhibition of keratinocyte apoptotic process|inhibition of keratinocyte apoptosis|downregulation of keratinocyte apoptosis|down-regulation of keratinocyte apoptotic process							rl	2013-05-29T14:36:15Z					biological_process											owl:Class	
GO:1902172	biolink:NamedThing	regulation of keratinocyte apoptotic process	Any process that modulates the frequency, rate or extent of keratinocyte apoptotic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of keratinocyte apoptosis							rl	2013-05-29T14:36:11Z					biological_process											owl:Class	
GO:0034112	biolink:NamedThing	positive regulation of homotypic cell-cell adhesion	Any process that activates or increases the frequency, rate, or extent of homotypic cell-cell adhesion.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0034289	biolink:NamedThing	detection of maltose stimulus	The series of events in which a maltose stimulus is received by a cell and converted into a molecular signal.	tmpzr1t_l9r_go_relaxed.owl	perception of maltose stimulus													biological_process											owl:Class	
GO:0034288	biolink:NamedThing	detection of disaccharide stimulus	The series of events in which a stimulus from a disaccharide is received and converted into a molecular signal.	tmpzr1t_l9r_go_relaxed.owl	perception of disaccharide stimulus													biological_process											owl:Class	
GO:0047079	biolink:NamedThing	deoxyuridine 1'-dioxygenase activity	Catalysis of the reaction: 2'-deoxyuridine + 2-oxoglutarate + O(2) = 2-deoxy-D-ribono-1,4-lactone + CO(2) + succinate + uracil.	tmpzr1t_l9r_go_relaxed.owl	pyrimidine-deoxynucleoside,2-oxoglutarate 1'-dioxygenase activity|2'-deoxyuridine,2-oxoglutarate:oxygen oxidoreductase (1'-hydroxylating)|pyrimidine-deoxynucleoside 1'-dioxygenase activity				RHEA:23316|EC:1.14.11.10|KEGG_REACTION:R02486|MetaCyc:1.14.11.10-RXN									molecular_function											owl:Class	
GO:0045986	biolink:NamedThing	negative regulation of smooth muscle contraction	Any process that stops, prevents, or reduces the frequency, rate or extent of smooth muscle contraction.	tmpzr1t_l9r_go_relaxed.owl	smooth muscle relaxation|down-regulation of smooth muscle contraction|down regulation of smooth muscle contraction|downregulation of smooth muscle contraction|inhibition of smooth muscle contraction													biological_process											owl:Class	
GO:0045932	biolink:NamedThing	negative regulation of muscle contraction	Any process that stops, prevents, or reduces the frequency, rate or extent of muscle contraction.	tmpzr1t_l9r_go_relaxed.owl	inhibition of muscle contraction|downregulation of muscle contraction|down-regulation of muscle contraction|down regulation of muscle contraction													biological_process											owl:Class	
GO:0016127	biolink:NamedThing	sterol catabolic process	The chemical reactions and pathways resulting in the breakdown of sterols, steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule.	tmpzr1t_l9r_go_relaxed.owl	sterol catabolism|sterol breakdown|sterol degradation													biological_process											owl:Class	
GO:0016125	biolink:NamedThing	sterol metabolic process	The chemical reactions and pathways involving sterols, steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule.	tmpzr1t_l9r_go_relaxed.owl	sterol metabolism													biological_process											owl:Class	
GO:0043772	biolink:NamedThing	acyl-phosphate glycerol-3-phosphate acyltransferase activity	Catalysis of the reaction: acyl phosphate + sn-glycerol 3-phosphate = 1-acyl-sn-glycerol 3-phosphate + orthophosphate.	tmpzr1t_l9r_go_relaxed.owl	acyl-phosphate:glycerol-3-phosphate acyltransferase activity|acylphosphate:glycerol-3-phosphate acyltransferase activity|acylphosphate glycerol-3-phosphate acyltransferase activity													molecular_function											owl:Class	
GO:0002688	biolink:NamedThing	regulation of leukocyte chemotaxis	Any process that modulates the frequency, rate, or extent of leukocyte chemotaxis.	tmpzr1t_l9r_go_relaxed.owl	regulation of leucocyte chemotaxis|regulation of immune cell chemotaxis													biological_process											owl:Class	
GO:0009809	biolink:NamedThing	lignin biosynthetic process	The chemical reactions and pathways resulting in the formation of lignins, a class of polymers formed by the dehydrogenetive radical polymerization of various phenylpropanoid monomers.	tmpzr1t_l9r_go_relaxed.owl	lignin anabolism|lignin biosynthesis|lignin synthesis|lignin formation				MetaCyc:PWY-361									biological_process											owl:Class	
GO:1904987	biolink:NamedThing	regulation of endothelial cell activation	Any process that modulates the frequency, rate or extent of endothelial cell activation.	tmpzr1t_l9r_go_relaxed.owl								bc	2016-02-29T16:16:09Z					biological_process											owl:Class	
GO:0004456	biolink:NamedThing	phosphogluconate dehydratase activity	Catalysis of the reaction: 6-phospho-D-gluconate = 2-dehydro-3-deoxy-6-phospho-D-gluconate + H(2)O.	tmpzr1t_l9r_go_relaxed.owl	gluconate 6-phosphate dehydratase activity|6-phosphogluconate dehydratase activity|6-phospho-D-gluconate hydro-lyase activity|6-phospho-D-gluconate hydro-lyase (2-dehydro-3-deoxy-6-phospho-D-gluconate-forming)|gluconate-6-phosphate dehydratase activity|6-phosphogluconate dehydrase activity|6-phosphogluconic dehydrase activity				RHEA:17277|MetaCyc:PGLUCONDEHYDRAT-RXN|EC:4.2.1.12|KEGG_REACTION:R02036									molecular_function											owl:Class	
GO:0033157	biolink:NamedThing	regulation of intracellular protein transport	Any process that modulates the frequency, rate or extent of the directed movement of proteins within cells.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0008817	biolink:NamedThing	cob(I)yrinic acid a,c-diamide adenosyltransferase activity	Catalysis of the reaction: ATP + cob(I)alamin + H2O = phosphate + diphosphate + adenosylcobalamin.	tmpzr1t_l9r_go_relaxed.owl	vitamin B12s adenosyltransferase activity|ATP:cob(I)alamin cobeta-adenosyltransferase activity|aquacob(I)alamin adenosyltransferase activity|ATP:corrinoid adenosyltransferase activity|cob(I)alamin adenosyltransferase activity|aquocob(I)alamin vitamin B12s adenosyltransferase activity|ATP:cob(I)yrinic acid-a,c-diamide cobeta-adenosyltransferase activity|ATP:cob(I)alamin Co-beta-adenosyltransferase activity|CobA				MetaCyc:COBALADENOSYLTRANS-RXN|RHEA:14725|Reactome:R-HSA-3159253|EC:2.5.1.17|Reactome:R-HSA-3322125									molecular_function											owl:Class	
GO:0042307	biolink:NamedThing	positive regulation of protein import into nucleus	Any process that activates or increases the frequency, rate or extent of movement of proteins from the cytoplasm into the nucleus.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of protein import into nucleus|activation of protein import into nucleus|positive regulation of protein transport from cytoplasm to nucleus|positive regulation of protein-nucleus import|upregulation of protein import into nucleus|up regulation of protein import into nucleus|stimulation of protein import into nucleus|positive regulation of protein import into cell nucleus													biological_process											owl:Class	
GO:0070169	biolink:NamedThing	positive regulation of biomineral tissue development	Any process that activates or increases the frequency, rate or extent of biomineral tissue development, the formation of hard tissues that consist mainly of inorganic compounds.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0036023	biolink:NamedThing	embryonic skeletal limb joint morphogenesis	The process, occurring in the embryo, in which the anatomical structures of a skeletal limb joint are generated and organized. A skeletal limb joint is the connecting structure between the bones of a limb.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-10-13T04:57:39Z					biological_process											owl:Class	
GO:0036022	biolink:NamedThing	limb joint morphogenesis	The process in which the anatomical structures of a limb joint are generated and organized. A limb joint is a flexible region that separates the rigid sections of a limb to allow movement in a controlled manner.	tmpzr1t_l9r_go_relaxed.owl	leg joint morphogenesis|knee morphogenesis							bf	2011-10-13T04:52:59Z					biological_process											owl:Class	
GO:1900588	biolink:NamedThing	violaceol I metabolic process	The chemical reactions and pathways involving violaceol I.	tmpzr1t_l9r_go_relaxed.owl	violaceol I metabolism							di	2012-05-15T06:50:48Z					biological_process											owl:Class	
GO:0061687	biolink:NamedThing	detoxification of inorganic compound	Any process that reduces or removes the toxicity of inorganic compounds. These include transport of such compounds away from sensitive areas and to compartments or complexes whose purpose is sequestration of inorganic compounds.	tmpzr1t_l9r_go_relaxed.owl								dph	2015-03-09T09:16:23Z					biological_process											owl:Class	
GO:0098836	biolink:NamedThing	cytoskeleton of dendritic spine	The portion of the cytoskeleton that lies within a dendritic spine.  The actin component of this cytoskeleton is involved in spine head remodelling in response to postsynaptic signalling.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0006217	biolink:NamedThing	deoxycytidine catabolic process	The chemical reactions and pathways resulting in the breakdown of deoxycytidine, 2-deoxyribosylcytosine, one of the four major nucleosides of DNA.	tmpzr1t_l9r_go_relaxed.owl	deoxycytidine catabolism|deoxycytidine degradation|deoxycytidine breakdown													biological_process											owl:Class	
GO:0046092	biolink:NamedThing	deoxycytidine metabolic process	The chemical reactions and pathways involving deoxycytidine, 2-deoxyribosylcytosine, one of the four major nucleosides of DNA.	tmpzr1t_l9r_go_relaxed.owl	deoxycytidine metabolism													biological_process											owl:Class	
GO:0004850	biolink:NamedThing	uridine phosphorylase activity	Catalysis of the reaction: uridine + phosphate = uracil + alpha-D-ribose 1-phosphate.	tmpzr1t_l9r_go_relaxed.owl	pyrimidine phosphorylase activity|UrdPase activity|uridine:phosphate alpha-D-ribosyltransferase activity|UPase activity|UPH				Reactome:R-HSA-74376|MetaCyc:URPHOS-RXN|RHEA:24388|Reactome:R-HSA-74372|EC:2.4.2.3									molecular_function											owl:Class	
GO:0017102	biolink:NamedThing	methionyl glutamyl tRNA synthetase complex	A complex consisting of methionyl- and glutamyl-tRNA synthetases. The tRNA synthetases present in the complex bind to their cognate tRNAs more efficiently than they do as monomers.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0010391	biolink:NamedThing	glucomannan metabolic process	The chemical reactions and pathways involving glucomannan, a polysaccharide composed of D-glucose and D-mannose. The mannose units form the backbone structure (a linear main chain) with the D-glucose as single side-units.	tmpzr1t_l9r_go_relaxed.owl	glucomannan metabolism													biological_process											owl:Class	
GO:0006080	biolink:NamedThing	substituted mannan metabolic process	The chemical reactions and pathways involving a mannan backbone composed of D-mannose unites, substituted with D-glucose and/or D-galactose units.	tmpzr1t_l9r_go_relaxed.owl	substituted mannan metabolism													biological_process											owl:Class	
GO:0102259	biolink:NamedThing	1,2-diacylglycerol acylhydrolase activity	Catalysis of the reaction: H2O + a 1,2-diacyl-sn-glycerol = a monoglyceride + a fatty acid.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-12434									molecular_function											owl:Class	
GO:0070130	biolink:NamedThing	negative regulation of mitochondrial translation	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA in a mitochondrion.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of mitochondrial protein synthesis|negative regulation of mitochondrial protein biosynthesis|negative regulation of mitochondrial protein formation|negative regulation of mitochondrial protein anabolism													biological_process											owl:Class	
GO:0032528	biolink:NamedThing	microvillus organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a microvillus, a thin cylindrical membrane-covered projection on the surface of a cell.	tmpzr1t_l9r_go_relaxed.owl	microvillus organisation|microvillus organization and biogenesis													biological_process											owl:Class	
GO:0120036	biolink:NamedThing	plasma membrane bounded cell projection organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a plasma membrane bounded prolongation or process extending from a cell, e.g. a cilium or axon.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/13298						krc	2017-04-26T16:07:02Z					biological_process											owl:Class	
GO:1903016	biolink:NamedThing	negative regulation of exo-alpha-sialidase activity	Any process that stops, prevents or reduces the frequency, rate or extent of exo-alpha-sialidase activity.	tmpzr1t_l9r_go_relaxed.owl	down regulation of neuraminidase activity|down regulation of acetylneuraminyl hydrolase activity|downregulation of N-acylneuraminate glycohydrolase activity|down-regulation of acetylneuraminidase activity|inhibition of neuraminidase activity|downregulation of sialidase activity|down regulation of acetylneuraminidase activity|inhibition of acetylneuraminyl hydrolase activity|inhibition of exo-alpha-sialidase activity|down-regulation of exo-alpha-sialidase activity|inhibition of N-acylneuraminate glycohydrolase activity|negative regulation of alpha-neuraminidase activity|inhibition of sialidase activity|down-regulation of sialidase activity|downregulation of acetylneuraminidase activity|downregulation of acetylneuraminyl hydrolase activity|negative regulation of N-acylneuraminate glycohydrolase activity|down regulation of alpha-neuraminidase activity|downregulation of neuraminidase activity|down regulation of N-acylneuraminate glycohydrolase activity|negative regulation of neuraminidase activity|down regulation of sialidase activity|negative regulation of sialidase activity|down-regulation of N-acylneuraminate glycohydrolase activity|down-regulation of alpha-neuraminidase activity|negative regulation of acetylneuraminyl hydrolase activity|down regulation of exo-alpha-sialidase activity|down-regulation of acetylneuraminyl hydrolase activity|downregulation of exo-alpha-sialidase activity|inhibition of acetylneuraminidase activity|inhibition of alpha-neuraminidase activity|down-regulation of neuraminidase activity|downregulation of alpha-neuraminidase activity|negative regulation of acetylneuraminidase activity					human serum amyloid P component (SAP) P02743 inhibits viral neuraminidase, NA (exo-alpha-sialidase activity) demonstrated in Figure 4A PMID:23544079, (IDA)		rl	2014-05-14T18:15:17Z					biological_process											owl:Class	
GO:1903015	biolink:NamedThing	regulation of exo-alpha-sialidase activity	Any process that modulates the frequency, rate or extent of exo-alpha-sialidase activity.	tmpzr1t_l9r_go_relaxed.owl	regulation of acetylneuraminyl hydrolase activity|regulation of N-acylneuraminate glycohydrolase activity|regulation of sialidase activity|regulation of neuraminidase activity|regulation of alpha-neuraminidase activity|regulation of acetylneuraminidase activity					human serum amyloid P component (SAP) P02743 inhibits viral neuraminidase, NA (exo-alpha-sialidase activity) demonstrated in Figure 4A PMID:23544079, (IDA)		rl	2014-05-14T18:15:11Z					biological_process											owl:Class	
GO:0033361	biolink:NamedThing	lysine biosynthetic process via diaminopimelate, dehydrogenase pathway	The chemical reactions and pathways resulting in the formation of lysine, via the intermediate diaminopimelate; in this pathway tetrahydrodipicolinate is converted to meso-diaminopimelate in a single enzymatic step.	tmpzr1t_l9r_go_relaxed.owl	lysine formation via diaminopimelate, dehydrogenase pathway|lysine anabolism via diaminopimelate, dehydrogenase pathway|lysine synthesis via diaminopimelate, dehydrogenase pathway|lysine biosynthesis via diaminopimelic acid, dehydrogenase pathway				MetaCyc:PWY-2942									biological_process											owl:Class	
GO:1900345	biolink:NamedThing	regulation of methane biosynthetic process from methanethiol	Any process that modulates the frequency, rate or extent of methane biosynthetic process from methanethiol.	tmpzr1t_l9r_go_relaxed.owl								tt	2012-04-06T02:09:49Z					biological_process											owl:Class	
GO:0042442	biolink:NamedThing	melatonin catabolic process	The chemical reactions and pathways resulting in the breakdown of melatonin (N-acetyl-5-methoxytryptamine).	tmpzr1t_l9r_go_relaxed.owl	melatonin catabolism|melatonin breakdown|melatonin degradation											GO:0042449		biological_process											owl:Class	
GO:0042447	biolink:NamedThing	hormone catabolic process	The chemical reactions and pathways resulting in the breakdown of any hormone, naturally occurring substances secreted by specialized cells that affects the metabolism or behavior of other cells possessing functional receptors for the hormone.	tmpzr1t_l9r_go_relaxed.owl	hormone catabolism|hormone breakdown|hormone degradation													biological_process											owl:Class	
GO:0044543	biolink:NamedThing	envenomation resulting in zymogen activation in other organism	The process which begins with venom being forced into an organism by the bite or sting of another organism, and ends with the proteolytic processing of an inactive enzyme to an active form.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-03-22T11:52:56Z					biological_process											owl:Class	
GO:0002851	biolink:NamedThing	positive regulation of peripheral T cell tolerance induction	Any process that activates or increases the frequency, rate, or extent of peripheral T cell tolerance induction.	tmpzr1t_l9r_go_relaxed.owl	up regulation of peripheral T cell tolerance induction|upregulation of peripheral T cell tolerance induction|activation of peripheral T cell tolerance induction|stimulation of peripheral T cell tolerance induction|up-regulation of peripheral T cell tolerance induction													biological_process											owl:Class	
GO:0002849	biolink:NamedThing	regulation of peripheral T cell tolerance induction	Any process that modulates the frequency, rate, or extent of peripheral T cell tolerance induction.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0047037	biolink:NamedThing	salutaridine reductase (NADPH) activity	Catalysis of the reaction: (7S)-salutaridinol + NADP(+) = H(+) + NADPH + salutaridine.	tmpzr1t_l9r_go_relaxed.owl	salutaridinol:NADP+ 7-oxidoreductase activity				EC:1.1.1.248|KEGG_REACTION:R04697|RHEA:10108|MetaCyc:1.1.1.248-RXN									molecular_function											owl:Class	
GO:1901495	biolink:NamedThing	negative regulation of cysteine metabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of cysteine metabolic process.	tmpzr1t_l9r_go_relaxed.owl	inhibition of cysteine metabolism|down-regulation of cysteine metabolic process|down-regulation of cysteine metabolism|downregulation of cysteine metabolic process|down regulation of cysteine metabolism|downregulation of cysteine metabolism|negative regulation of cysteine metabolism|down regulation of cysteine metabolic process|inhibition of cysteine metabolic process							vw	2012-10-16T14:28:47Z					biological_process											owl:Class	
GO:1900170	biolink:NamedThing	negative regulation of glucocorticoid mediated signaling pathway	Any process that stops, prevents or reduces the frequency, rate or extent of glucocorticoid mediated signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	downregulation of glucocorticoid mediated signalling|inhibition of glucocorticoid mediated signaling pathway|downregulation of glucocorticoid mediated signaling pathway|down regulation of glucocorticoid mediated signalling|inhibition of glucocorticoid mediated signalling|negative regulation of glucocorticoid mediated signalling|down-regulation of glucocorticoid mediated signalling|down-regulation of glucocorticoid mediated signaling pathway|down regulation of glucocorticoid mediated signaling pathway							hjd	2012-03-08T08:33:20Z					biological_process											owl:Class	
GO:0070320	biolink:NamedThing	inward rectifier potassium channel inhibitor activity	Binds to and stops, prevents, or reduces the activity of an inwardly rectifying potassium channel.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0140678	biolink:NamedThing	molecular function inhibitor activity	A molecular function regulator that inhibits or decreases the activity of its target via non-covalent binding that does not result in covalent modification to the target.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/21782						pg	2021-07-07T07:24:32Z					molecular_function											owl:Class	
GO:0033201	biolink:NamedThing	alpha-1,4-glucan synthase activity	Catalysis of the reaction: RDP-glucose + [alpha-D-glucosyl-(1,4)]n = RDP + [alpha-D-glucosyl-(1,4)]n+1, where RDP is ADP or UDP.	tmpzr1t_l9r_go_relaxed.owl	1,4-alpha-glucan synthase activity				EC:2.4.1.21|RHEA:18189									molecular_function											owl:Class	
GO:0030124	biolink:NamedThing	AP-4 adaptor complex	An AP-type membrane coat adaptor complex that consists of beta4, epsilon, mu4 and sigma4 subunits and is found associated with membranes in the trans-Golgi network; it is not clear whether AP-4 forms clathrin coats in vivo.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0030119	biolink:NamedThing	AP-type membrane coat adaptor complex	Any of several heterotetrameric complexes that link clathrin (or another coat-forming molecule, as hypothesized for AP-3 and AP-4) to a membrane surface; they are found on coated pits and coated vesicles, and mediate sorting of cargo proteins into vesicles. Each AP complex contains two large (a beta and one of either an alpha, gamma, delta, or epsilon) subunits (110-130 kDa), a medium (mu) subunit (approximately 50 kDa), and a small (sigma) subunit (15-20 kDa).	tmpzr1t_l9r_go_relaxed.owl	clathrin adaptor													cellular_component											owl:Class	
GO:0015193	biolink:NamedThing	L-proline transmembrane transporter activity	Enables the transfer of L-proline from one side of a membrane to the other. L-proline is pyrrolidine-2-carboxylic acid.	tmpzr1t_l9r_go_relaxed.owl	glycine betaine/proline porter activity|L-proline transporter activity|L-proline permease activity|proline/glycine/betaine:hydrogen/sodium symporter activity				Reactome:R-HSA-8870354							GO:0005296		molecular_function											owl:Class	
GO:2000907	biolink:NamedThing	negative regulation of glucomannan catabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of glucomannan catabolic process.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of glucomannan catabolism							tt	2011-07-29T01:13:24Z					biological_process											owl:Class	
GO:0060307	biolink:NamedThing	regulation of ventricular cardiac muscle cell membrane repolarization	Any process that modulates the establishment or extent of a membrane potential in the polarizing direction towards the resting potential in a ventricular cardiomyocyte.	tmpzr1t_l9r_go_relaxed.owl	regulation of ventricular cardiac muscle repolarization|electrocardiogram T wave|ventricular repolarization|regulation of ventricular cardiac muscle cell repolarization|regulation of ventricular cardiomyocyte membrane repolarization													biological_process											owl:Class	
GO:0110095	biolink:NamedThing	cellular detoxification of aldehyde	Any process carried out at the cellular level that reduces or removes the toxicity of an aldehyde. These may include transport of aldehydes away from sensitive areas and to compartments or complexes whose purpose is sequestration of the toxic substance.	tmpzr1t_l9r_go_relaxed.owl								kmv	2018-02-16T21:19:20Z					biological_process											owl:Class	
GO:1902689	biolink:NamedThing	negative regulation of NAD metabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of NAD metabolic process.	tmpzr1t_l9r_go_relaxed.owl	downregulation of NAD metabolism|inhibition of NAD (oxidized) metabolism|down regulation of NAD (oxidized) metabolic process|down-regulation of NAD (oxidized) metabolism|negative regulation of NAD (oxidized) metabolism|down-regulation of nicotinamide adenine dinucleotide metabolic process|inhibition of nicotinamide adenine dinucleotide metabolism|down-regulation of oxidized NAD metabolic process|down-regulation of oxidized nicotinamide adenine dinucleotide metabolic process|negative regulation of oxidized nicotinamide adenine dinucleotide metabolism|down regulation of oxidized nicotinamide adenine dinucleotide metabolic process|down-regulation of oxidized nicotinamide adenine dinucleotide metabolism|negative regulation of oxidized NAD metabolic process|down regulation of nicotinamide adenine dinucleotide metabolic process|inhibition of oxidized NAD metabolism|down regulation of NAD metabolic process|inhibition of NAD metabolic process|down regulation of NAD metabolism|inhibition of NAD phosphorylation and dephosphorylation|downregulation of NAD (oxidized) metabolic process|inhibition of nicotinamide adenine dinucleotide metabolic process|inhibition of oxidized NAD metabolic process|down regulation of nicotinamide adenine dinucleotide metabolism|negative regulation of oxidized NAD metabolism|downregulation of oxidized NAD metabolism|negative regulation of oxidized nicotinamide adenine dinucleotide metabolic process|downregulation of NAD (oxidized) metabolism|inhibition of NAD metabolism|down-regulation of oxidized NAD metabolism|down regulation of oxidized NAD metabolic process|down-regulation of nicotinamide adenine dinucleotide metabolism|downregulation of NAD phosphorylation and dephosphorylation|inhibition of oxidized nicotinamide adenine dinucleotide metabolic process|down-regulation of NAD metabolic process|down regulation of oxidized NAD metabolism|downregulation of oxidized NAD metabolic process|downregulation of nicotinamide adenine dinucleotide metabolism|negative regulation of nicotinamide adenine dinucleotide metabolism|negative regulation of NAD (oxidized) metabolic process|down regulation of NAD (oxidized) metabolism|down-regulation of NAD phosphorylation and dephosphorylation|inhibition of oxidized nicotinamide adenine dinucleotide metabolism|down regulation of NAD phosphorylation and dephosphorylation|downregulation of oxidized nicotinamide adenine dinucleotide metabolic process|inhibition of NAD (oxidized) metabolic process|down-regulation of NAD (oxidized) metabolic process|negative regulation of NAD phosphorylation and dephosphorylation|downregulation of oxidized nicotinamide adenine dinucleotide metabolism|downregulation of NAD metabolic process|down regulation of oxidized nicotinamide adenine dinucleotide metabolism|downregulation of nicotinamide adenine dinucleotide metabolic process|negative regulation of NAD metabolism|down-regulation of NAD metabolism|negative regulation of nicotinamide adenine dinucleotide metabolic process							di	2014-02-12T18:58:59Z					biological_process											owl:Class	
GO:0086002	biolink:NamedThing	cardiac muscle cell action potential involved in contraction	An action potential that occurs in a cardiac muscle cell and is involved in its contraction.	tmpzr1t_l9r_go_relaxed.owl								tb	2011-11-10T07:45:11Z					biological_process											owl:Class	
GO:0007272	biolink:NamedThing	ensheathment of neurons	The process in which glial cells envelop neuronal cell bodies and/or axons to form an insulating layer. This can take the form of myelinating or non-myelinating ensheathment.	tmpzr1t_l9r_go_relaxed.owl	ionic insulation of neurons by glial cells													biological_process											owl:Class	
GO:0060391	biolink:NamedThing	positive regulation of SMAD protein signal transduction	Any process that increases the rate, frequency or extent of SMAD protein signal transduction. Pathway-restricted SMAD proteins and common-partner SMAD proteins are involved in the transforming growth factor beta receptor signaling pathways.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of SMAD protein import into nucleus|positive regulation of SMAD protein nuclear translocation													biological_process											owl:Class	
GO:0032878	biolink:NamedThing	regulation of establishment or maintenance of cell polarity	Any process that modulates the frequency, rate or extent of the specification, formation or maintenance of anisotropic intracellular organization or cell growth patterns.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0008356	biolink:NamedThing	asymmetric cell division	The asymmetric division of cells to produce two daughter cells with different developmental potentials. It is of fundamental significance for the generation of cell diversity.	tmpzr1t_l9r_go_relaxed.owl	asymmetrical cytokinesis|asymmetric cytokinesis|asymmetrical cell division				Wikipedia:Asymmetric_cell_division									biological_process											owl:Class	
GO:2000679	biolink:NamedThing	positive regulation of transcription regulatory region DNA binding	Any process that activates or increases the frequency, rate or extent of transcription regulatory region DNA binding.	tmpzr1t_l9r_go_relaxed.owl								yaf	2011-05-09T03:28:17Z					biological_process											owl:Class	
GO:0102662	biolink:NamedThing	malonate-semialdehyde dehydrogenase (acetylating, NAD+) activity	Catalysis of the reaction: 3-oxopropanoate + coenzyme A(4-) + NAD(1-) <=> acetyl-CoA(4-) + carbon dioxide + NADH(2-).	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-2902|RHEA:22992									molecular_function											owl:Class	
GO:0035403	biolink:NamedThing	histone kinase activity (H3-T6 specific)	Catalysis of the transfer of a phosphate group to the threonine-6 residue of the N-terminal tail of histone H3.	tmpzr1t_l9r_go_relaxed.owl	histone threonine kinase activity (H3-T6 specific)|histone-threonine kinase activity (H3-T6 specific)							bf	2010-03-24T10:05:39Z					molecular_function											owl:Class	
GO:0006537	biolink:NamedThing	glutamate biosynthetic process	The chemical reactions and pathways resulting in the formation of glutamate, the anion of 2-aminopentanedioic acid.	tmpzr1t_l9r_go_relaxed.owl	glutamate biosynthetic process, using glutamate synthase (NADPH)|glutamic acid biosynthesis|glutamate biosynthesis, using glutamate synthase (NADPH)|glutamate anabolism|glutamic acid biosynthetic process|glutamate biosynthesis|glutamate synthesis|glutamate formation|glutamate biosynthetic process, using glutamate dehydrogenase (NAD(P)+)|glutamate biosynthesis, using glutamate dehydrogenase (NAD(P)+)													biological_process											owl:Class	
GO:1901557	biolink:NamedThing	response to fenofibrate	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fenofibrate stimulus.	tmpzr1t_l9r_go_relaxed.owl								hp	2012-11-02T09:46:20Z					biological_process											owl:Class	
GO:0031652	biolink:NamedThing	positive regulation of heat generation	Any process that activates or increases the rate or extent of heat generation.	tmpzr1t_l9r_go_relaxed.owl	up regulation of heat generation|stimulation of heat generation|activation of heat generation|upregulation of heat generation|up-regulation of heat generation													biological_process											owl:Class	
GO:0097428	biolink:NamedThing	protein maturation by iron-sulfur cluster transfer	The transfer of an assembled iron-sulfur cluster from a scaffold protein to an acceptor protein that contributes to the attainment of the full functional capacity of a protein.	tmpzr1t_l9r_go_relaxed.owl								pr	2012-11-15T09:59:06Z					biological_process											owl:Class	
GO:1900849	biolink:NamedThing	regulation of pseurotin A biosynthetic process	Any process that modulates the frequency, rate or extent of pseurotin A biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of Pseurotin synthesis|regulation of pseurotin A formation|regulation of Pseurotin biosynthesis|regulation of Pseurotin formation|regulation of Pseurotin anabolism|regulation of Pseurotin biosynthetic process|regulation of pseurotin A biosynthesis|regulation of pseurotin A anabolism|regulation of pseurotin A synthesis							di	2012-06-07T09:45:27Z					biological_process											owl:Class	
GO:0042821	biolink:NamedThing	pyridoxal biosynthetic process	The chemical reactions and pathways resulting in the formation of 3-hydroxy-5-(hydroxymethyl)-2-methyl-4-pyridinecarboxaldehyde, one of the vitamin B6 compounds.	tmpzr1t_l9r_go_relaxed.owl	pyridoxal anabolism|pyridoxal formation|pyridoxal biosynthesis|pyridoxal synthesis													biological_process											owl:Class	
GO:0060960	biolink:NamedThing	cardiac neuron fate commitment	The process in which the developmental fate of a cell becomes restricted such that it will develop into a neuron of the heart.	tmpzr1t_l9r_go_relaxed.owl	heart neuron fate commitment							dph	2009-09-30T10:23:47Z					biological_process											owl:Class	
GO:0120070	biolink:NamedThing	negative regulation of stomach fundus smooth muscle contraction	Any process that decreases the frequency, rate or extent of any stomach fundus smooth muscle contraction.	tmpzr1t_l9r_go_relaxed.owl								krc	2017-06-13T23:27:40Z					biological_process											owl:Class	
GO:0030954	biolink:NamedThing	astral microtubule nucleation	The 'de novo' formation of an astral microtubule, in which tubulin heterodimers form metastable oligomeric aggregates, some of which go on to support formation of a complete microtubule.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0070241	biolink:NamedThing	positive regulation of activated T cell autonomous cell death	Any process that activates or increases the frequency, rate or extent of activated T cell autonomous cell death.	tmpzr1t_l9r_go_relaxed.owl	activation of activated T cell autonomous cell death|positive regulation of activated T lymphocyte autonomous cell death|up regulation of activated T cell autonomous cell death|upregulation of activated T cell autonomous cell death|positive regulation of activated T-cell autonomous cell death|up-regulation of activated T cell autonomous cell death|positive regulation of activated T-lymphocyte autonomous cell death|positive regulation of activated cell autonomous cell death|positive regulation of activated T cell apoptosis|positive regulation of ACAD|stimulation of activated T cell autonomous cell death													biological_process											owl:Class	
GO:0071321	biolink:NamedThing	cellular response to cGMP	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cGMP (cyclic GMP, guanosine 3',5'-cyclophosphate) stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to guanosine 3',5'-cyclophosphate|cellular response to 3',5'-cGMP|cellular response to 3',5' cGMP|cellular response to cyclic GMP							mah	2009-12-10T05:12:58Z					biological_process											owl:Class	
GO:0061451	biolink:NamedThing	retrotrapezoid nucleus development	The progression of the retrotrapezoid nucleus (RTN) over time from it's initial formation to its mature state. The retrotrapezoid nucleus is a group of neurons in the rostral medulla, which are responsible regulating respiration.	tmpzr1t_l9r_go_relaxed.owl								dph	2012-07-19T12:38:30Z					biological_process											owl:Class	
GO:0106360	biolink:NamedThing	2-hydroxy-3-methylhexadecanoyl-CoA lyase activity	Catalysis of the reaction: 2-hydroxy-3-methylhexadecanoyl-CoA = 2-methylpentadecanal + formyl-CoA.	tmpzr1t_l9r_go_relaxed.owl					RHEA:25379			hjd	2021-02-03T16:14:49Z					molecular_function											owl:Class	
GO:0106359	biolink:NamedThing	2-hydroxyacyl-CoA lyase activity	Catalysis of the reaction: A 2-hydroxyacyl-CoA = formyl-CoA + a propanol.	tmpzr1t_l9r_go_relaxed.owl								hjd	2021-02-03T16:12:00Z					molecular_function											owl:Class	
GO:0031067	biolink:NamedThing	negative regulation of histone deacetylation at centromere	Any process that stops, prevents, or reduces the frequency, rate or extent of the removal of acetyl groups to histones in centromeric DNA.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of histone deacetylation at centromere|inhibition of histone deacetylation at centromere|downregulation of histone deacetylation at centromere|down regulation of histone deacetylation at centromere													biological_process											owl:Class	
GO:0031066	biolink:NamedThing	regulation of histone deacetylation at centromere	Any process that modulates the frequency, rate or extent of the removal of acetyl groups from histones in centromeric DNA.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0097316	biolink:NamedThing	cellular response to N-acetyl-D-glucosamine	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an N-acetyl-D-glucosamine stimulus.	tmpzr1t_l9r_go_relaxed.owl								pr	2012-05-30T04:01:02Z					biological_process											owl:Class	
GO:0097315	biolink:NamedThing	response to N-acetyl-D-glucosamine	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an N-acetyl-D-glucosamine stimulus.	tmpzr1t_l9r_go_relaxed.owl								pr	2012-05-30T03:58:54Z					biological_process											owl:Class	
GO:0046294	biolink:NamedThing	formaldehyde catabolic process	The chemical reactions and pathways resulting in the breakdown of formaldehyde (methanal, H2C=O), the simplest aldehyde.	tmpzr1t_l9r_go_relaxed.owl	formaldehyde breakdown|methanal catabolism|methanal catabolic process|formaldehyde catabolism|formaldehyde degradation													biological_process											owl:Class	
GO:0046292	biolink:NamedThing	formaldehyde metabolic process	The chemical reactions and pathways involving formaldehyde (methanal, H2C=O), a colorless liquid or gas with a pungent odor, commonly used as a fixative or an antibacterial agent.	tmpzr1t_l9r_go_relaxed.owl	methanal metabolism|methanal metabolic process|formaldehyde metabolism													biological_process											owl:Class	
GO:0060623	biolink:NamedThing	regulation of chromosome condensation	Any process that modulates the rate, frequency, or extent of chromosome condensation, the progressive compaction of dispersed interphase chromatin into threadlike chromosomes prior to mitotic or meiotic nuclear division, or during apoptosis, in eukaryotic cells.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-05-18T02:12:13Z					biological_process											owl:Class	
GO:0061673	biolink:NamedThing	mitotic spindle astral microtubule	Any of the mitotic spindle microtubules that radiate in all directions from the spindle poles and are thought to contribute to the forces that separate the poles and position them in relation to the rest of the cell.	tmpzr1t_l9r_go_relaxed.owl								dph	2014-12-08T18:27:20Z					cellular_component											owl:Class	
GO:0000235	biolink:NamedThing	astral microtubule	Any of the spindle microtubules that radiate in all directions from the spindle poles and are thought to contribute to the forces that separate the poles and position them in relation to the rest of the cell.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0035943	biolink:NamedThing	estrone secretion	The regulated release of estrone into the circulatory system.	tmpzr1t_l9r_go_relaxed.owl	folliculin secretion|3-hydroxy-1,3,5(10)-estratrien-17-one secretion							bf	2011-07-25T02:18:40Z					biological_process											owl:Class	
GO:1902863	biolink:NamedThing	regulation of embryonic camera-type eye development	Any process that modulates the frequency, rate or extent of embryonic camera-type eye development.	tmpzr1t_l9r_go_relaxed.owl	regulation of embryonic eye development							mr	2014-04-03T15:24:00Z					biological_process											owl:Class	
GO:1903339	biolink:NamedThing	negative regulation of cell wall organization or biogenesis	Any process that stops, prevents or reduces the frequency, rate or extent of cell wall organization or biogenesis.	tmpzr1t_l9r_go_relaxed.owl	down regulation of cellular cell wall organization or biogenesis|down-regulation of cell wall organisation or biogenesis|down regulation of cell wall organization or biogenesis at cellular level|down regulation of cell wall organization or biogenesis|downregulation of cell wall organisation or biogenesis|negative regulation of cell wall organization or biogenesis at cellular level|downregulation of cellular cell wall organization or biogenesis|downregulation of cellular cell wall organisation or biogenesis|inhibition of cell wall organisation or biogenesis|inhibition of cellular cell wall organization or biogenesis|negative regulation of cellular cell wall organization or biogenesis|down-regulation of cell wall organization or biogenesis at cellular level|negative regulation of cell wall organisation or biogenesis|inhibition of cell wall organization or biogenesis at cellular level|downregulation of cell wall organization or biogenesis|inhibition of cellular cell wall organisation or biogenesis|down-regulation of cellular cell wall organization or biogenesis|inhibition of cell wall organization or biogenesis|down regulation of cellular cell wall organisation or biogenesis|down-regulation of cellular cell wall organisation or biogenesis|downregulation of cell wall organization or biogenesis at cellular level|down regulation of cell wall organisation or biogenesis|negative regulation of cellular cell wall organisation or biogenesis|down-regulation of cell wall organization or biogenesis							vw	2014-08-18T13:20:58Z					biological_process											owl:Class	
GO:0047775	biolink:NamedThing	citramalate CoA-transferase activity	Catalysis of the reaction: acetyl-CoA + citramalate = acetate + (3S)-citramalyl-CoA.	tmpzr1t_l9r_go_relaxed.owl	acetyl-CoA:citramalate CoA-transferase activity				MetaCyc:CITRAMALATE-COA-TRANSFERASE-RXN|EC:2.8.3.11|RHEA:17621									molecular_function											owl:Class	
GO:0019457	biolink:NamedThing	methionine catabolic process to succinyl-CoA	The chemical reactions and pathways resulting in the breakdown of methionine into other compounds, including succinyl-CoA.	tmpzr1t_l9r_go_relaxed.owl	methionine degradation to succinyl-CoA|methionine breakdown to succinyl-CoA				MetaCyc:METHIONINE-DEG1-PWY									biological_process											owl:Class	
GO:0006104	biolink:NamedThing	succinyl-CoA metabolic process	The chemical reactions and pathways involving succinyl-CoA, a compound composed of the monovalent acyl group 3-carboxypropanoyl, derived from succinic acid by loss of one OH group, linked to coenzyme A.	tmpzr1t_l9r_go_relaxed.owl	succinyl-CoA metabolism													biological_process											owl:Class	
GO:0106367	biolink:NamedThing	(deoxy)nucleoside phosphate kinase activity, dGTP as phosphate donor	Catalysis of the reaction: a 2'-deoxyribonucleoside 5'-phosphate + dGTP = a 2'-deoxyribonucleoside 5'-diphosphate + dGDP.	tmpzr1t_l9r_go_relaxed.owl					RHEA:62128			hjd	2021-03-11T20:06:53Z					molecular_function											owl:Class	
GO:0010490	biolink:NamedThing	UDP-4-keto-rhamnose-4-keto-reductase activity	Catalysis of the reaction: UDP-4-keto-rhamnose + NADPH = UDP-rhamnose + NADP+.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0060411	biolink:NamedThing	cardiac septum morphogenesis	The process in which the anatomical structure of a cardiac septum is generated and organized. A cardiac septum is a partition that separates parts of the heart.	tmpzr1t_l9r_go_relaxed.owl	heart septum morphogenesis											GO:0003280		biological_process											owl:Class	
GO:0008727	biolink:NamedThing	GDP-mannose mannosyl hydrolase activity	Catalysis of the reaction: GDP-alpha-D-mannose + H2O = GDP + D-mannose + H+.	tmpzr1t_l9r_go_relaxed.owl					RHEA:28102|MetaCyc:GDPMANMANHYDRO-RXN									molecular_function											owl:Class	
GO:0097069	biolink:NamedThing	cellular response to thyroxine stimulus	A change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a thyroxine stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to T4 stimulus							pr	2011-06-14T05:06:48Z					biological_process											owl:Class	
GO:0007604	biolink:NamedThing	phototransduction, UV	The sequence of reactions within a cell required to convert absorbed photons from UV light into a molecular signal; ultraviolet radiation is electromagnetic radiation with a wavelength in the range of 10 to 400 nanometers.	tmpzr1t_l9r_go_relaxed.owl	phototransduction, UV light|UV-sensitive opsin|phototransduction, ultraviolet radiation|phototransduction, UV radiation|phototransduction, ultraviolet light													biological_process											owl:Class	
GO:0009589	biolink:NamedThing	detection of UV	The series of events in which an ultraviolet radiation (UV light) stimulus is received and converted into a molecular signal. Ultraviolet radiation is electromagnetic radiation with a wavelength in the range of 10 to 380 nanometers.	tmpzr1t_l9r_go_relaxed.owl	detection of ultraviolet radiation stimulus|detection of ultraviolet light stimulus|detection of UV radiation stimulus|perception of UV|detection of UV light stimulus													biological_process											owl:Class	
GO:1900453	biolink:NamedThing	negative regulation of long-term synaptic depression	Any process that stops, prevents or reduces the frequency, rate or extent of long term synaptic depression.	tmpzr1t_l9r_go_relaxed.owl	downregulation of LTD|negative regulation of long term depression|down regulation of long term synaptic depression|downregulation of long term synaptic depression|down-regulation of long term depression|down-regulation of long term synaptic depression|inhibition of LTD|downregulation of long term depression|down regulation of long term depression|down-regulation of LTD|negative regulation of LTD|down regulation of LTD|inhibition of long term depression|inhibition of long term synaptic depression|negative regulation of long term synaptic depression							rl	2012-04-27T03:55:14Z					biological_process											owl:Class	
GO:0043525	biolink:NamedThing	positive regulation of neuron apoptotic process	Any process that activates or increases the frequency, rate or extent of cell death of neurons by apoptotic process.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of programmed cell death, neurons|up-regulation of neuron apoptosis|upregulation of neuron apoptosis|positive regulation of neuron apoptosis|stimulation of neuron apoptosis|up regulation of neuron apoptosis|activation of neuron apoptosis													biological_process											owl:Class	
GO:1900978	biolink:NamedThing	negative regulation of tatiopterin metabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of tatiopterin metabolic process.	tmpzr1t_l9r_go_relaxed.owl	inhibition of tatiopterin metabolic process|down regulation of tatiopterin metabolic process|negative regulation of tatiopterin metabolism|down regulation of tatiopterin metabolism|inhibition of tatiopterin metabolism|downregulation of tatiopterin metabolism|down-regulation of tatiopterin metabolic process|down-regulation of tatiopterin metabolism|downregulation of tatiopterin metabolic process							tt	2012-06-14T04:03:29Z					biological_process											owl:Class	
GO:2001191	biolink:NamedThing	regulation of gamma-delta T cell activation involved in immune response	Any process that modulates the frequency, rate or extent of gamma-delta T cell activation involved in immune response.	tmpzr1t_l9r_go_relaxed.owl	regulation of gamma-delta T lymphocyte activation during immune response|regulation of gamma-delta T cell activation during immune response|regulation of gamma-delta T-lymphocyte activation during immune response|regulation of gamma-delta T-cell activation during immune response							yaf	2011-11-03T04:28:38Z					biological_process											owl:Class	
GO:0034115	biolink:NamedThing	negative regulation of heterotypic cell-cell adhesion	Any process that stops, prevents, or reduces the frequency, rate, or extent of heterotypic cell-cell adhesion.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0090027	biolink:NamedThing	negative regulation of monocyte chemotaxis	Any process that decreases the frequency, rate, or extent of monocyte chemotaxis.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-08-03T10:19:40Z					biological_process											owl:Class	
GO:1903445	biolink:NamedThing	protein transport from ciliary membrane to plasma membrane	The directed movement of protein from ciliary membrane to plasma membrane.	tmpzr1t_l9r_go_relaxed.owl								pr	2014-09-18T07:46:10Z					biological_process											owl:Class	
GO:0061951	biolink:NamedThing	establishment of protein localization to plasma membrane	The directed movement of a protein to a specific location in a plasma membrane.	tmpzr1t_l9r_go_relaxed.owl								dph	2017-10-26T12:55:15Z					biological_process											owl:Class	
GO:0106369	biolink:NamedThing	(deoxy)nucleoside phosphate kinase activity, GTP as phosphate donor	Catalysis of the reaction: a 2'-deoxyribonucleoside 5'-phosphate + GTP = a 2'-deoxyribonucleoside 5'-diphosphate + GDP.	tmpzr1t_l9r_go_relaxed.owl					RHEA:62124			hjd	2021-03-11T20:12:21Z					molecular_function											owl:Class	
GO:0106048	biolink:NamedThing	spermidine deacetylation	The modification of acetylspermadine by the removal of acetyl groups.	tmpzr1t_l9r_go_relaxed.owl	N8-acetylspermidine deacetylation							hjd	2017-08-01T18:39:17Z					biological_process											owl:Class	
GO:0106047	biolink:NamedThing	polyamine deacetylation	The modification of acetylpolyamine by the removal of acetyl groups.	tmpzr1t_l9r_go_relaxed.owl								hjd	2017-08-01T18:36:46Z					biological_process											owl:Class	
GO:0010081	biolink:NamedThing	regulation of inflorescence meristem growth	Any process involved in maintaining the size and shape of an inflorescence meristem.	tmpzr1t_l9r_go_relaxed.owl	regulation of inflorescence meristem size													biological_process											owl:Class	
GO:0003364	biolink:NamedThing	lamellipodium assembly involved in mesendodermal cell migration	Formation of a lamellipodium, a thin sheetlike extension of the surface of a migrating cell that contributes to the directed self-propelled movement of a mesendodermal cell.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-12-08T04:46:39Z					biological_process											owl:Class	
GO:0120108	biolink:NamedThing	DNA-3'-diphospho-5'-guanosine diphosphatase	Catalysis of the reaction: (DNA)-3'-diphospho-5'-guanosine + H(2)O <=> (DNA)-3'-phosphate + GMP.	tmpzr1t_l9r_go_relaxed.owl	DNA-3'pp5'G guanylate hydrolase				RHEA:52140|EC:3.6.1.72			krc	2017-10-17T22:12:59Z					molecular_function											owl:Class	
GO:0016788	biolink:NamedThing	hydrolase activity, acting on ester bonds	Catalysis of the hydrolysis of any ester bond.	tmpzr1t_l9r_go_relaxed.owl	esterase activity				Reactome:R-HSA-9023619|Reactome:R-HSA-162729|Reactome:R-HSA-9023617|EC:3.1.-.-									molecular_function											owl:Class	
GO:0006259	biolink:NamedThing	DNA metabolic process	Any cellular metabolic process involving deoxyribonucleic acid. This is one of the two main types of nucleic acid, consisting of a long, unbranched macromolecule formed from one, or more commonly, two, strands of linked deoxyribonucleotides.	tmpzr1t_l9r_go_relaxed.owl	cellular DNA metabolism|DNA metabolism											GO:0055132		biological_process											owl:Class	
GO:0098934	biolink:NamedThing	retrograde dendritic transport	The directed movement of organelles or molecules along microtubules in a dendrite from the postsynapse towards the cell body.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0098935	biolink:NamedThing	dendritic transport	The directed movement of organelles or molecules along microtubules in dendrites.	tmpzr1t_l9r_go_relaxed.owl	dendrite cargo transport													biological_process											owl:Class	
GO:0044012	biolink:NamedThing	histone acetyltransferase activity (H2A-K9 specific)	Catalysis of the reaction: acetyl-CoA + histone H2A L-lysine (position 9) = CoA + histone H2A N6-acetyl-L-lysine (position 9).	tmpzr1t_l9r_go_relaxed.owl	histone lysine N-acetyltransferase activity (H2A-K9 specific)													molecular_function											owl:Class	
GO:2000551	biolink:NamedThing	regulation of T-helper 2 cell cytokine production	Any process that modulates the frequency, rate or extent of T-helper 2 cell cytokine production.	tmpzr1t_l9r_go_relaxed.owl	regulation of Th2 cell cytokine production							ebc	2011-04-03T07:32:47Z					biological_process											owl:Class	
GO:0019879	biolink:NamedThing	peptidyl-thyronine biosynthetic process from peptidyl-tyrosine	The formation of peptidyl-thyronine from peptidyl-tyrosine in thyroglobulin by phenyl transfer coupled with the formation of peptidyl-dehydroalanine.	tmpzr1t_l9r_go_relaxed.owl	peptidyl-thyronine anabolism from peptidyl-tyrosine|peptidyl-thyronine synthesis from peptidyl-tyrosine|peptidyl-thyronine formation from peptidyl-tyrosine					See also the biological process term 'peptidyl-dehydroalanine biosynthetic process from peptidyl-tyrosine or peptidyl-serine ; GO:0018250'.								biological_process											owl:Class	
GO:0010550	biolink:NamedThing	regulation of PSII associated light-harvesting complex II catabolic process	Any process that modulates the chemical reactions and pathways resulting in the breakdown of one or more components of the light-harvesting complex of photosystem II.	tmpzr1t_l9r_go_relaxed.owl	regulation of LHCII catabolism|regulation of LHCII degradation													biological_process											owl:Class	
GO:0010974	biolink:NamedThing	negative regulation of division septum assembly	Any process that decreases the frequency, rate or extent of division septum formation. division septum formation is he assembly and arrangement of a septum that spans the plasma membrane interface between progeny cells following cytokinesis.	tmpzr1t_l9r_go_relaxed.owl	inhibition of division septum assembly involved in cell cycle cytokinesis|negative regulation of division septum formation							tb	2009-06-01T10:32:32Z			GO:1902469|GO:1901139		biological_process											owl:Class	
GO:0009245	biolink:NamedThing	lipid A biosynthetic process	The chemical reactions and pathways resulting in the formation of lipid A, the glycolipid group of bacterial lipopolysaccharides, consisting of four to six fatty acyl chains linked to two glucosamine residues. Further modifications of the backbone are common.	tmpzr1t_l9r_go_relaxed.owl	lipid A biosynthesis|lipid A synthesis|lipid A anabolism|lipid A formation				MetaCyc:NAGLIPASYN-PWY									biological_process											owl:Class	
GO:0072659	biolink:NamedThing	protein localization to plasma membrane	A process in which a protein is transported to, or maintained in, a specific location in the plasma membrane.	tmpzr1t_l9r_go_relaxed.owl	protein localisation in plasma membrane|protein localization in plasma membrane|protein-plasma membrane targeting|protein targeting to plasma membrane							tb	2009-07-10T10:29:23Z			GO:0090002|GO:0072661		biological_process											owl:Class	
GO:1904381	biolink:NamedThing	Golgi apparatus mannose trimming	Any protein alpha-1,2-demannosylation that takes place in the Golgi apparatus.	tmpzr1t_l9r_go_relaxed.owl	mannose trimming in Golgi apparatus|protein alpha-1,2-demannosylation in Golgi apparatus|protein alpha-1,2-demannosylation in Golgi complex|glycoprotein mannose trimming in Golgi apparatus|glycoprotein mannose trimming in Golgi ribbon|glycoprotein mannose trimming in Golgi complex|mannose trimming in cis-Golgi|protein alpha-1,2-demannosylation in Golgi ribbon|mannose trimming in Golgi							bf	2015-06-23T09:42:06Z					biological_process											owl:Class	
GO:0000753	biolink:NamedThing	cell morphogenesis involved in conjugation with cellular fusion	The change in form (cell shape and size) that occurs during sexual reproduction in order to facilitate direct contact between the compatible mating types in organisms that undergo conjugation cellular fusion.	tmpzr1t_l9r_go_relaxed.owl	shmoo orientation|shmooing											GO:0007332		biological_process											owl:Class	
GO:0000767	biolink:NamedThing	cell morphogenesis involved in conjugation	The change in form (cell shape and size) that occurs during sexual reproduction in order to facilitate direct contact between the compatible mating types.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0046730	biolink:NamedThing	induction by virus of host immune response	The induction by a virus of an immune response in the host organism.	tmpzr1t_l9r_go_relaxed.owl	passive viral induction of cell-mediated immune response in host|passive induction of host immune response by virus|passive induction of host innate immune response by virus|passive viral activation of innate immune response in host|activation of host immune response by virus|active viral induction of host immune response|passive induction of host cell-mediated immune response by virus|passive induction of innate immune response in host by virus|passive activation of host immune response by virus|passive viral activation of humoral immune response in host|passive viral induction of humoral immune response in host|passive viral induction of innate immune response in host|passive viral induction of host immune response|passive induction of cell-mediated immune response in host by virus|active induction of host immune response by virus|passive induction of humoral immune response in host by virus|passive induction of host humoral immune response by virus|passive viral activation of cell-mediated immune response in host											GO:0046732|GO:0046731|GO:0046733|GO:0046735|GO:0046734		biological_process											owl:Class	
GO:0003875	biolink:NamedThing	ADP-ribosylarginine hydrolase activity	Catalysis of the reaction: N2-(ADP-D-ribosyl)-L-arginine + H2O = L-arginine + ADP-ribose.	tmpzr1t_l9r_go_relaxed.owl	nomega-(ADP-D-ribosyl)-L-arginine ADP-ribosylhydrolase activity|N(omega)-(ADP-D-ribosyl)-L-arginine ADP-ribosylhydrolase activity|ADP-ribose-L-arginine cleavage enzyme activity|omega-protein-N-(ADP-D-ribosyl)-L-arginine ADP-ribosylhydrolase activity|protein-nomega-(ADP-D-ribosyl)-L-arginine ADP-ribosylhydrolase activity|protein ADP-ribosylarginine hydrolase activity|ADP-ribose-L-arginine cleaving enzyme activity|ADPribosylarginine hydrolase activity				RHEA:20784|EC:3.2.2.19|MetaCyc:ADP-RIBOSYLARGININE-HYDROLASE-RXN									molecular_function											owl:Class	
GO:0061949	biolink:NamedThing	regulation of premature acrosome loss	Any process that modulates the rate, frequency or extent of the discharge, by sperm, of a single, anterior secretory granule before the sperm reaches to the zona pellucida of the oocyte. The process begins with the fusion of the outer acrosomal membrane with the sperm plasma membrane and ends with the exocytosis of the acrosomal contents.	tmpzr1t_l9r_go_relaxed.owl								dph	2017-10-25T17:51:32Z					biological_process											owl:Class	
GO:0097107	biolink:NamedThing	postsynaptic density assembly	The aggregation, arrangement and bonding together of a set of components to form a postsynaptic density, a region that lies adjacent to the cytoplasmic face of the postsynaptic membrane at excitatory synapse.	tmpzr1t_l9r_go_relaxed.owl	post-synaptic density assembly|post synaptic density assembly|PSD assembly							pr	2011-07-27T05:21:39Z					biological_process											owl:Class	
GO:0070609	biolink:NamedThing	regulation of fungal-type cell wall (1->3)-alpha-glucan metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds, found in the walls of ascospores.	tmpzr1t_l9r_go_relaxed.owl	regulation of ascospore wall 1,3-alpha-glucan metabolism|regulation of ascospore wall alpha-1,3 glucan metabolic process|regulation of fungal-type cell wall 1,3-alpha-glucan metabolic process|regulation of ascospore wall alpha-1,3 glucan metabolism							mah	2009-04-29T01:29:02Z					biological_process											owl:Class	
GO:0090275	biolink:NamedThing	negative regulation of somatostatin secretion	Any process that decreases the rate, frequency, extent of the regulated release of somatostatin from secretory granules in the D cells of the pancreas.	tmpzr1t_l9r_go_relaxed.owl								tb	2010-02-05T02:54:14Z					biological_process											owl:Class	
GO:0090278	biolink:NamedThing	negative regulation of peptide hormone secretion	Any process that decreases the rate, frequency, or extent of the regulated release of a peptide hormone from secretory granules.	tmpzr1t_l9r_go_relaxed.owl								tb	2010-02-05T02:56:39Z					biological_process											owl:Class	
GO:1904603	biolink:NamedThing	regulation of advanced glycation end-product receptor activity	Any process that modulates the frequency, rate or extent of advanced glycation end-product receptor activity.	tmpzr1t_l9r_go_relaxed.owl	regulation of RAGE activity|regulation of AGE receptor activity							krc	2015-08-26T16:24:49Z					biological_process											owl:Class	
GO:0051224	biolink:NamedThing	negative regulation of protein transport	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a protein into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of protein transport|inhibition of protein transport|downregulation of protein transport|down regulation of protein transport													biological_process											owl:Class	
GO:0097544	biolink:NamedThing	ciliary shaft	The mid part of a cilium between the ciliary base and ciliary tip that extends into the extracellular space.	tmpzr1t_l9r_go_relaxed.owl	cilial shaft|flagellum shaft|flagellar shaft|cilium shaft					Note that 'ciliary shaft' is sparingly used in the literature to denote the projecting part of the cilium; many authors would refer to the axoneme instead. However, the definition of GO:0005930 'axoneme' is rather stringent, and the localization of many ciliary proteins would not fit that definition. Also, note that cilia and eukaryotic flagella are deemed to be equivalent.		pr	2013-12-12T11:17:30Z					cellular_component											owl:Class	
GO:0033528	biolink:NamedThing	S-methylmethionine cycle	A cyclic series of interconversions involving S-methyl-L-methionine, S-adenosyl-L-homocysteine, S-adenosyl-L-methionine, L-homocysteine, and L-methionine. Converts the methionine group of adenosylmethionine back to free methionine, and may serve regulate the cellular adenosylmethionine level.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:PWY-5441									biological_process											owl:Class	
GO:0090507	biolink:NamedThing	phenylethylamine metabolic process involved in synaptic transmission	The chemical reactions and pathways involving phenylethylamine that contribute to synaptic transmission.	tmpzr1t_l9r_go_relaxed.owl								tb	2012-11-15T15:06:08Z					biological_process											owl:Class	
GO:0003904	biolink:NamedThing	deoxyribodipyrimidine photo-lyase activity	Catalysis of the reaction: cyclobutadipyrimidine (in DNA) = 2 pyrimidine residues (in DNA). This reaction represents the reactivation of irradiated DNA by light.	tmpzr1t_l9r_go_relaxed.owl	deoxyribodipyrimidine photolyase activity|DNA cyclobutane dipyrimidine photolyase activity|photolyase activity|PhrB photolyase activity|deoxyribocyclobutadipyrimidine pyrimidine-lyase activity|CPD photolyase activity|deoxyribonucleic cyclobutane dipyrimidine photolyase activity|photoreactivating enzyme activity|DNA-photoreactivating enzyme|deoxyribonucleate pyrimidine dimer lyase (photosensitive)|PRE|phr A photolyase activity|dipyrimidine photolyase (photosensitive)|deoxyribonucleic photolyase activity				MetaCyc:DEOXYRIBODIPYRIMIDINE-PHOTOLYASE-RXN|RHEA:10672|EC:4.1.99.3									molecular_function											owl:Class	
GO:0003913	biolink:NamedThing	DNA photolyase activity	Catalysis of the repair of a photoproduct resulting from ultraviolet irradiation of two adjacent pyrimidine residues in DNA.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:DEOXYRIBODIPYRIMIDINE-PHOTOLYASE-RXN									molecular_function											owl:Class	
GO:0140639	biolink:NamedThing	positive regulation of pyroptosis	Any process that increases the frequency, rate or extent of pyroptosis.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/21399						pg	2021-05-11T05:19:17Z					biological_process											owl:Class	
GO:1904107	biolink:NamedThing	protein localization to microvillus membrane	A process in which a protein is transported to, or maintained in, a location within a microvillus membrane.	tmpzr1t_l9r_go_relaxed.owl	protein localization in microvillus membrane|protein localisation in microvillus membrane|protein localisation to microvillus membrane							kmv	2015-04-01T18:14:48Z					biological_process											owl:Class	
GO:0097330	biolink:NamedThing	response to 5-fluoro-2'-deoxyuridine	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 5-fluoro-2'-deoxyuridine stimulus. 5-fluoro-2'-deoxyuridine is a pyrimidine 2'-deoxyribonucleoside compound having 5-fluorouracil as the nucleobase; it is used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract.	tmpzr1t_l9r_go_relaxed.owl								pr	2012-06-12T10:53:35Z					biological_process											owl:Class	
GO:0032834	biolink:NamedThing	positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response	Any process that activates or increases the frequency, rate or extent of differentiation of CD4-positive, CD25-positive, alpha-beta regulatory T cells as part of an immune response.	tmpzr1t_l9r_go_relaxed.owl	activation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation during immune response|positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation during immune response|positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell development involved in immune response|stimulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation during immune response|positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T lymphocyte differentiation during immune response|up regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation during immune response|positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T-cell differentiation during immune response|up-regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation during immune response|positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T-lymphocyte differentiation during immune response|upregulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation during immune response					Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.								biological_process											owl:Class	
GO:0019234	biolink:NamedThing	sensory perception of fast pain	The series of events required for an organism to receive a fast pain stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process. Fast pain is often subjectively described as a sharp or stabbing pain; in humans, the signals from a fast pain stimulus are perceived and relayed along myelinated A-delta fibers to the central nervous system, reaching their target in about 0.1 seconds.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0019233	biolink:NamedThing	sensory perception of pain	The series of events required for an organism to receive a painful stimulus, convert it to a molecular signal, and recognize and characterize the signal. Pain is medically defined as the physical sensation of discomfort or distress caused by injury or illness, so can hence be described as a harmful stimulus which signals current (or impending) tissue damage. Pain may come from extremes of temperature, mechanical damage, electricity or from noxious chemical substances. This is a neurological process.	tmpzr1t_l9r_go_relaxed.owl	nociception|perception of physiological pain				Wikipedia:Nociception									biological_process											owl:Class	
GO:0071802	biolink:NamedThing	negative regulation of podosome assembly	Any process that stops, prevents or reduces the rate or extent of podosome assembly.	tmpzr1t_l9r_go_relaxed.owl	inhibition of podosome assembly|downregulation of podosome assembly|down regulation of podosome assembly|down-regulation of podosome assembly							mah	2010-09-03T01:49:14Z					biological_process											owl:Class	
GO:0016819	biolink:NamedThing	hydrolase activity, acting on acid anhydrides, in sulfonyl-containing anhydrides	Catalysis of the hydrolysis of any acid anhydride which contains a sulfonyl group, -SO2-.	tmpzr1t_l9r_go_relaxed.owl	hydrolase activity, acting on acid anhydrides, in sulphonyl-containing anhydrides				EC:3.6.2.-									molecular_function											owl:Class	
GO:0060730	biolink:NamedThing	regulation of intestinal epithelial structure maintenance	Any process that modulates the rate, frequency, or extent of intestinal epithelial structure maintenance, a tissue homeostatic process required for the maintenance of the structure of the intestinal epithelium.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-06-12T01:49:34Z					biological_process											owl:Class	
GO:1902967	biolink:NamedThing	protein localization to mitotic spindle midzone	A process in which a protein is transported to, or maintained in, a location within a mitotic spindle midzone.	tmpzr1t_l9r_go_relaxed.owl	protein localization in mitotic spindle midzone|protein localisation to mitotic spindle midzone|protein localisation in mitotic spindle midzone							mah	2014-05-06T14:40:01Z					biological_process											owl:Class	
GO:0030889	biolink:NamedThing	negative regulation of B cell proliferation	Any process that stops, prevents or reduces the rate or extent of B cell proliferation.	tmpzr1t_l9r_go_relaxed.owl	down regulation of B cell proliferation|downregulation of B cell proliferation|inhibition of B cell proliferation|down-regulation of B cell proliferation|negative regulation of B-lymphocyte proliferation|negative regulation of B-cell proliferation|negative regulation of B lymphocyte proliferation													biological_process											owl:Class	
GO:0102509	biolink:NamedThing	cyanidin 3,5-diglucoside glucosidase activity	Catalysis of the reaction: cyanin betaine + H2O <=> cyanidin 3-O-beta-D-glucoside betaine + beta-D-glucose.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-14436									molecular_function											owl:Class	
GO:0016497	biolink:NamedThing	substance K receptor activity	Combining with substance K, the peptide His-Lys-Thr-Asp-Ser-Phe-Val-Gly-Leu-Met, to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	neurokinin A receptor activity|neuromedin L receptor activity													molecular_function											owl:Class	
GO:0004995	biolink:NamedThing	tachykinin receptor activity	Combining with a tachykinin neuropeptide and transmitting the signal across the membrane by activating an associated G-protein.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0072279	biolink:NamedThing	convergent extension involved in metanephric nephron morphogenesis	The morphogenetic process in which the renal epithelium narrows along one axis and lengthens in a perpendicular axis that contributes to the shaping of a nephron in the metanephros.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-04-01T03:16:11Z					biological_process											owl:Class	
GO:0001197	biolink:NamedThing	positive regulation of mating-type specific transcription from RNA polymerase II promoter	Any mating-type specific process that activates or increases the rate of transcription from an RNA polymerase II promoter.	tmpzr1t_l9r_go_relaxed.owl	up regulation of transcription from an RNA polymerase II promoter, mating-type specific|up-regulation of transcription from an RNA polymerase II promoter, mating-type specific|stimulation of transcription from an RNA polymerase II promoter, mating-type specific|upregulation of transcription from an RNA polymerase II promoter, mating-type specific|activation of transcription from an RNA polymerase II promoter, mating-type specific							krc	2011-11-23T09:31:33Z					biological_process											owl:Class	
GO:1990457	biolink:NamedThing	pexophagosome	A membrane-bounded intracellular vesicle involved in the degradation of peroxisome by macropexophagy.	tmpzr1t_l9r_go_relaxed.owl								dhl	2014-08-15T18:51:53Z					cellular_component											owl:Class	
GO:0030173	biolink:NamedThing	integral component of Golgi membrane	The component of the Golgi membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.	tmpzr1t_l9r_go_relaxed.owl	Golgi integral membrane protein|integral to Golgi membrane													cellular_component											owl:Class	
GO:0097187	biolink:NamedThing	dentinogenesis	The process whose specific outcome is the formation of dentin, the mineralized tissue that constitutes the major bulk of teeth. Dentin may be one of three types: primary dentin, secondary dentin, and tertiary dentin.	tmpzr1t_l9r_go_relaxed.owl	dentine development|dentin development							pr	2011-11-21T09:04:17Z					biological_process											owl:Class	
GO:0015364	biolink:NamedThing	dicarboxylate:inorganic phosphate antiporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: dicarboxylate(out) + inorganic phosphate(in) = dicarboxylate(in) + inorganic phosphate(out).	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0021930	biolink:NamedThing	cerebellar granule cell precursor proliferation	The multiplication or reproduction of neuroblasts that will give rise to granule cells. A granule cell is a glutamatergic interneuron found in the cerebellar cortex.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0043063	biolink:NamedThing	intercellular bridge organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the intracellular bridge. An intracellular bridge is a direct link between the cytoplasms of sister cells that allows cells to communicate with one another.	tmpzr1t_l9r_go_relaxed.owl	intercellular bridge organisation|intercellular bridge organization and biogenesis													biological_process											owl:Class	
GO:0043062	biolink:NamedThing	extracellular structure organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of structures in the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane, and also covers the host cell environment outside an intracellular parasite.	tmpzr1t_l9r_go_relaxed.owl	extracellular structure organization and biogenesis|extracellular structure organisation													biological_process											owl:Class	
GO:1904648	biolink:NamedThing	cellular response to rotenone	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a rotenone stimulus.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-08-31T20:55:39Z					biological_process											owl:Class	
GO:1904647	biolink:NamedThing	response to rotenone	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a rotenone stimulus.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-08-31T20:55:32Z					biological_process											owl:Class	
GO:1905296	biolink:NamedThing	negative regulation of neural crest cell fate specification	Any process that stops, prevents or reduces the frequency, rate or extent of neural crest cell fate specification.	tmpzr1t_l9r_go_relaxed.owl	down regulation of neural crest cell fate specification|downregulation of neural crest cell fate specification|down-regulation of neural crest cell fate specification|inhibition of neural crest cell fate specification							rl	2016-06-28T15:14:49Z					biological_process											owl:Class	
GO:0065009	biolink:NamedThing	regulation of molecular function	Any process that modulates the frequency, rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding.	tmpzr1t_l9r_go_relaxed.owl	regulation of a molecular function													biological_process											owl:Class	
GO:0102818	biolink:NamedThing	lycopene cleavage oxygenase activity	Catalysis of the reaction: lycopene + 2 O2 <=> 2 sulcatone + bixin aldehyde.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-8236									molecular_function											owl:Class	
GO:1900118	biolink:NamedThing	negative regulation of execution phase of apoptosis	Any process that stops, prevents or reduces the frequency, rate or extent of execution phase of apoptosis.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of execution phase of apoptosis|inhibition of execution phase of apoptosis|down regulation of execution phase of apoptosis|downregulation of execution phase of apoptosis							pr	2012-02-22T11:26:24Z					biological_process											owl:Class	
GO:1900117	biolink:NamedThing	regulation of execution phase of apoptosis	Any process that modulates the frequency, rate or extent of execution phase of apoptosis.	tmpzr1t_l9r_go_relaxed.owl								pr	2012-02-22T11:26:20Z					biological_process											owl:Class	
GO:0098544	biolink:NamedThing	maintenance of protein complex location	Any process in which a protein complex is maintained in a location and prevented from moving elsewhere. These include sequestration, stabilization to prevent transport elsewhere and the active retrieval of protein complexes that move away.	tmpzr1t_l9r_go_relaxed.owl								dos	2013-11-15T18:20:16Z					biological_process											owl:Class	
GO:1901851	biolink:NamedThing	7,8-didemethyl-8-hydroxy-5-deazariboflavin catabolic process	The chemical reactions and pathways resulting in the breakdown of 7,8-didemethyl-8-hydroxy-5-deazariboflavin.	tmpzr1t_l9r_go_relaxed.owl	coenzyme F0 catabolism|7,8-didemethyl-8-hydroxy-5-deazariboflavin catabolism|coenzyme F0 catabolic process|coenzyme F0 breakdown|7,8-didemethyl-8-hydroxy-5-deazariboflavin degradation|coenzyme F0 degradation|7,8-didemethyl-8-hydroxy-5-deazariboflavin breakdown							yaf	2013-01-28T11:38:36Z					biological_process											owl:Class	
GO:0047334	biolink:NamedThing	diphosphate-fructose-6-phosphate 1-phosphotransferase activity	Catalysis of the reaction: fructose-6-phosphate + diphosphate = phosphate + fructose-1,6-bisphosphate.	tmpzr1t_l9r_go_relaxed.owl	6-phosphofructokinase (diphosphate) activity|diphosphate-dependent 6-phosphofructose-1-kinase activity|pyrophosphate-fructose 6-phosphate phosphotransferase activity|6-phosphofructokinase (pyrophosphate) activity|pyrophosphate-dependent 6-phosphofructose-1-kinase activity|diphosphate:D-fructose-6-phosphate 1-phosphotransferase activity|pyrophosphate-dependent phosphofructo-1-kinase activity|pyrophosphate--fructose 6-phosphate 1-phosphotransferase activity|inorganic pyrophosphate-dependent phosphofructokinase activity|inorganic pyrophosphate-phosphofructokinase activity				MetaCyc:2.7.1.90-RXN|EC:2.7.1.90|RHEA:13613									molecular_function											owl:Class	
GO:0099084	biolink:NamedThing	postsynaptic specialization organization	A process that results in the assembly, arrangement of constituent parts, or disassembly of a postsynaptic specialization, a structure that lies adjacent to the cytoplasmic face of the postsynaptic membrane.	tmpzr1t_l9r_go_relaxed.owl	post synaptic specialization organization|postsynaptic specialization organisation|post-synaptic specialization organization							pr	2011-07-27T05:17:12Z					biological_process											owl:Class	
GO:0042126	biolink:NamedThing	nitrate metabolic process	The chemical reactions and pathways involving nitrates, inorganic or organic salts and esters of nitric acid.	tmpzr1t_l9r_go_relaxed.owl	nitrate metabolism													biological_process											owl:Class	
GO:1901119	biolink:NamedThing	tobramycin metabolic process	The chemical reactions and pathways involving tobramycin.	tmpzr1t_l9r_go_relaxed.owl	tobramycin metabolism							yaf	2012-07-11T03:15:19Z					biological_process											owl:Class	
GO:0098660	biolink:NamedThing	inorganic ion transmembrane transport	The process in which an inorganic ion is transported across a membrane.	tmpzr1t_l9r_go_relaxed.owl	inorganic ion membrane transport|transmembrane inorganic ion transport					Note that this term is not intended for use in annotating lateral movement within membranes.								biological_process											owl:Class	
GO:0010598	biolink:NamedThing	NAD(P)H dehydrogenase complex (plastoquinone)	Complex that possesses NAD(P)H dehydrogenase (plastoquinone) activity. The complex is one of the components of the electron transport chain. It is involved in electron transport from an unidentified electron donor, possibly NADH, NADPH or ferredoxin(Fd) to the plastoquinone pool.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0035825	biolink:NamedThing	homologous recombination	A DNA recombination process that results in the exchange of an equal amount of genetic material between highly homologous DNA molecules.	tmpzr1t_l9r_go_relaxed.owl	interchromosomal DNA recombination|chromosomal crossover|reciprocal DNA recombination|interstrand DNA recombination	https://github.com/geneontology/go-ontology/issues/18777			Wikipedia:Chromosomal_crossover			bf	2011-05-04T01:23:31Z					biological_process											owl:Class	
GO:0098987	biolink:NamedThing	regulation of modification of synapse structure, modulating synaptic transmission	Any process that regulates the modification of synaptic structure and as a result regulates synaptic transmission.	tmpzr1t_l9r_go_relaxed.owl						Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.								biological_process											owl:Class	
GO:0008816	biolink:NamedThing	citryl-CoA lyase activity	Catalysis of the reaction: (3S)-citryl-CoA = acetyl-CoA + oxaloacetate.	tmpzr1t_l9r_go_relaxed.owl	(3S)-citryl-CoA oxaloacetate-lyase activity|(3S)-citryl-CoA oxaloacetate-lyase (acetyl-CoA-forming)				EC:4.1.3.34|MetaCyc:CITRYLY-RXN|RHEA:20812									molecular_function											owl:Class	
GO:1903690	biolink:NamedThing	negative regulation of wound healing, spreading of epidermal cells	Any process that stops, prevents or reduces the frequency, rate or extent of wound healing, spreading of epidermal cells.	tmpzr1t_l9r_go_relaxed.owl	downregulation of wound healing, spreading of epidermal cells|down-regulation of wound healing, spreading of epidermal cells|down regulation of wound healing, spreading of epidermal cells|inhibition of wound healing, spreading of epidermal cells							als	2014-12-01T15:54:27Z					biological_process											owl:Class	
GO:1901727	biolink:NamedThing	positive regulation of histone deacetylase activity	Any process that activates or increases the frequency, rate or extent of histone deacetylase activity.	tmpzr1t_l9r_go_relaxed.owl	up regulation of histone deacetylase activity|upregulation of histone deacetylase activity|up-regulation of histone deacetylase activity|activation of histone deacetylase activity							rl	2013-01-07T09:14:21Z					biological_process											owl:Class	
GO:0090045	biolink:NamedThing	positive regulation of deacetylase activity	Any process that activates or increases the frequency, rate or extent of deacetylase activity, the catalysis of the hydrolysis of an acetyl group or groups from a substrate molecule.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-08-03T12:00:14Z					biological_process											owl:Class	
GO:0035855	biolink:NamedThing	megakaryocyte development	The process whose specific outcome is the progression of a megakaryocyte cell over time, from its formation to the mature structure. Megakaryocyte development does not include the steps involved in committing a cell to a megakaryocyte fate. A megakaryocyte is a giant cell 50 to 100 micron in diameter, with a greatly lobulated nucleus, found in the bone marrow.	tmpzr1t_l9r_go_relaxed.owl	megakaryocyte cell development							bf	2011-05-13T01:28:06Z					biological_process											owl:Class	
GO:0042539	biolink:NamedThing	hypotonic salinity response	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.	tmpzr1t_l9r_go_relaxed.owl	response to hypotonic salt stress													biological_process											owl:Class	
GO:1902092	biolink:NamedThing	positive regulation of fumagillin biosynthetic process	Any process that activates or increases the frequency, rate or extent of fumagillin biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of fumagillin biosynthetic process|activation of fumagillin formation|up-regulation of fumagillin formation|activation of fumagillin biosynthesis|activation of fumagillin synthesis|positive regulation of fumagillin synthesis|up regulation of fumagillin anabolism|up regulation of fumagillin synthesis|upregulation of fumagillin anabolism|up regulation of fumagillin formation|positive regulation of fumagillin biosynthesis|positive regulation of fumagillin formation|upregulation of fumagillin biosynthesis|activation of fumagillin anabolism|up-regulation of fumagillin anabolism|activation of fumagillin biosynthetic process|upregulation of fumagillin synthesis|positive regulation of fumagillin anabolism|upregulation of fumagillin formation|up regulation of fumagillin biosynthetic process|upregulation of fumagillin biosynthetic process|up regulation of fumagillin biosynthesis|up-regulation of fumagillin biosynthesis|up-regulation of fumagillin synthesis							di	2013-04-27T03:45:09Z					biological_process											owl:Class	
GO:0031351	biolink:NamedThing	integral component of plastid membrane	The component of the plastid membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.	tmpzr1t_l9r_go_relaxed.owl	integral to plastid membrane													cellular_component											owl:Class	
GO:0000228	biolink:NamedThing	nuclear chromosome	A chromosome that encodes the nuclear genome and is found in the nucleus of a eukaryotic cell during the cell cycle phases when the nucleus is intact.	tmpzr1t_l9r_go_relaxed.owl	nuclear interphase chromosome													cellular_component											owl:Class	
GO:0060100	biolink:NamedThing	positive regulation of phagocytosis, engulfment	Any process that activates or increases the frequency, rate or extent of the internalization of bacteria, immune complexes and other particulate matter or of an apoptotic cell by phagocytosis.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0060099	biolink:NamedThing	regulation of phagocytosis, engulfment	Any process that modulates the frequency, rate or extent of the internalization of bacteria, immune complexes and other particulate matter or of an apoptotic cell by phagocytosis.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0007295	biolink:NamedThing	growth of a germarium-derived egg chamber	Growth of the egg chamber between the time it leaves the germarium and the onset of vitellogenesis. During this time both nurse cells and the oocyte undergo developmental changes including nuclear organization and cytoplasmic growth. An example of this is found in Drosophila melanogaster.	tmpzr1t_l9r_go_relaxed.owl	egg chamber growth													biological_process											owl:Class	
GO:0042501	biolink:NamedThing	serine phosphorylation of STAT protein	The process of introducing a phosphate group to a serine residue of a STAT (Signal Transducer and Activator of Transcription) protein.	tmpzr1t_l9r_go_relaxed.owl	serine phosphorylation of STAT3 protein											GO:0033136		biological_process											owl:Class	
GO:0070767	biolink:NamedThing	BRCA1-Rad51 complex	A protein complex that contains BRCA1 and Rad 51, and is involved in the control of recombination and of genome integrity.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-06-29T05:04:21Z					cellular_component											owl:Class	
GO:0019928	biolink:NamedThing	peptide cross-linking via 3-(S-L-cysteinyl)-L-aspartic acid	The cross-linking of a cysteine residue to an aspartic acid residue to form 3-(S-L-cysteinyl)-L-aspartic acid.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0314									biological_process											owl:Class	
GO:0106395	biolink:NamedThing	positive regulation of palmitic acid catabolic process	Any process that activates or increases the frequency, rate or extent of a palmitic acid catabolic process.	tmpzr1t_l9r_go_relaxed.owl								hjd	2021-10-08T15:30:08Z					biological_process											owl:Class	
GO:2000740	biolink:NamedThing	negative regulation of mesenchymal stem cell differentiation	Any process that stops, prevents or reduces the frequency, rate or extent of mesenchymal stem cell differentiation.	tmpzr1t_l9r_go_relaxed.owl								yaf	2011-06-14T02:31:31Z					biological_process											owl:Class	
GO:2000739	biolink:NamedThing	regulation of mesenchymal stem cell differentiation	Any process that modulates the frequency, rate or extent of mesenchymal stem cell differentiation.	tmpzr1t_l9r_go_relaxed.owl								yaf	2011-06-14T02:31:27Z					biological_process											owl:Class	
GO:0030277	biolink:NamedThing	maintenance of gastrointestinal epithelium	Protection of epithelial surfaces of the gastrointestinal tract from proteolytic and caustic digestive agents.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0004556	biolink:NamedThing	alpha-amylase activity	Catalysis of the endohydrolysis of (1->4)-alpha-D-glucosidic linkages in polysaccharides containing three or more alpha-(1->4)-linked D-glucose units.	tmpzr1t_l9r_go_relaxed.owl	1,4-alpha-D-glucan glucanohydrolase activity|glycogenase activity|alpha amylase activity|taka-amylase A|endoamylase activity				Reactome:R-HSA-191114|MetaCyc:RXN-1825|MetaCyc:ALPHA-AMYL-RXN|EC:3.2.1.1|MetaCyc:RXN-1823|Reactome:R-HSA-188979									molecular_function											owl:Class	
GO:0016160	biolink:NamedThing	amylase activity	Catalysis of the hydrolysis of amylose or an amylose derivative.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0009093	biolink:NamedThing	cysteine catabolic process	The chemical reactions and pathways resulting in the breakdown of cysteine, 2-amino-3-mercaptopropanoic acid.	tmpzr1t_l9r_go_relaxed.owl	cysteine degradation|cysteine breakdown|cysteine catabolism				Wikipedia:Cysteine									biological_process											owl:Class	
GO:0071454	biolink:NamedThing	cellular response to anoxia	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating a decline in oxygen levels to trace amounts, <0.1%.	tmpzr1t_l9r_go_relaxed.owl	cellular response to anaerobic conditions|cellular response to anoxic stress					Note that this term should not be confused with 'cellular response to hypoxia ; GO:0071456'.		mah	2009-12-16T04:44:20Z					biological_process											owl:Class	
GO:0048048	biolink:NamedThing	embryonic eye morphogenesis	The process occurring in the embryo by which the anatomical structures of the post-embryonic eye are generated and organized.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0048592	biolink:NamedThing	eye morphogenesis	The process in which the anatomical structures of the eye are generated and organized.	tmpzr1t_l9r_go_relaxed.owl												GO:0048748		biological_process											owl:Class	
GO:1904779	biolink:NamedThing	regulation of protein localization to centrosome	Any process that modulates the frequency, rate or extent of protein localization to centrosome.	tmpzr1t_l9r_go_relaxed.owl	regulation of protein localisation to centrosome					An example is cdk-2 in C. elegans (UniProt ID O61847) in PMID:17115027 (inferred from mutant phenotype).		es	2015-10-30T11:54:30Z					biological_process											owl:Class	
GO:2000568	biolink:NamedThing	positive regulation of memory T cell activation	Any process that activates or increases the frequency, rate or extent of memory T cell activation.	tmpzr1t_l9r_go_relaxed.owl								ebc	2011-04-03T09:10:12Z					biological_process											owl:Class	
GO:0051962	biolink:NamedThing	positive regulation of nervous system development	Any process that activates, maintains or increases the frequency, rate or extent of nervous system development, the origin and formation of nervous tissue.	tmpzr1t_l9r_go_relaxed.owl	up regulation of nervous system development|up-regulation of nervous system development|stimulation of nervous system development|activation of nervous system development|upregulation of nervous system development													biological_process											owl:Class	
GO:0032808	biolink:NamedThing	lacrimal gland development	The process whose specific outcome is the progression of the lacrimal gland over time, from its formation to the mature structure. The lacrimal gland produces secretions that lubricate and protect the cornea of the eye.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0071824	biolink:NamedThing	protein-DNA complex subunit organization	Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a protein-DNA complex.	tmpzr1t_l9r_go_relaxed.owl	protein-DNA complex subunit organisation|DNA-protein complex subunit organization							mah	2010-09-08T10:03:26Z					biological_process											owl:Class	
GO:1903403	biolink:NamedThing	negative regulation of renal phosphate excretion	Any process that stops, prevents or reduces the frequency, rate or extent of renal phosphate excretion.	tmpzr1t_l9r_go_relaxed.owl	down regulation of renal phosphate excretion|down regulation of renal phosphate ion excretion|down-regulation of renal phosphate excretion|inhibition of renal phosphate ion excretion|downregulation of renal phosphate ion excretion|negative regulation of renal phosphate ion excretion|inhibition of renal phosphate excretion|downregulation of renal phosphate excretion|down-regulation of renal phosphate ion excretion							pm	2014-09-01T13:47:10Z					biological_process											owl:Class	
GO:0019294	biolink:NamedThing	keto-3-deoxy-D-manno-octulosonic acid biosynthetic process	The chemical reactions and pathways resulting in the formation of keto-3-deoxy-D-manno-octulosonic acid, an acidic sugar present in lipopolysaccharides of the outer membranes of some Gram-negative bacteria.	tmpzr1t_l9r_go_relaxed.owl	keto-3-deoxy-D-manno-octulosonic acid formation|keto-3-deoxy-D-manno-octulosonic acid synthesis|keto-3-deoxy-D-manno-octulosonic acid biosynthesis|KDO biosynthetic process|ketodeoxyoctanoate biosynthetic process|KDO biosynthesis|keto-3-deoxy-D-manno-octulosonic acid anabolism				MetaCyc:KDOSYN-PWY									biological_process											owl:Class	
GO:0006232	biolink:NamedThing	TDP biosynthetic process	The chemical reactions and pathways resulting in the formation of TDP, ribosylthymine diphosphate.	tmpzr1t_l9r_go_relaxed.owl	TDP anabolism|TDP synthesis|TDP biosynthesis|TDP formation													biological_process											owl:Class	
GO:0048454	biolink:NamedThing	sepal structural organization	The process that contributes to the act of creating the structural organization of the sepal. This process pertains to the physical shaping of a rudimentary structure.	tmpzr1t_l9r_go_relaxed.owl	sepal structural organisation											GO:0048424		biological_process											owl:Class	
GO:0098917	biolink:NamedThing	retrograde trans-synaptic signaling	Cell-cell signaling from post to pre-synapse, across the synaptic cleft.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0099537	biolink:NamedThing	trans-synaptic signaling	Cell-cell signaling in either direction across the synaptic cleft.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1902164	biolink:NamedThing	positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator	Any process that activates or increases the frequency, rate or extent of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator.	tmpzr1t_l9r_go_relaxed.owl	activation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator|up regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator|upregulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator|up-regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator							lb	2013-05-22T12:39:29Z					biological_process											owl:Class	
GO:0031903	biolink:NamedThing	microbody membrane	The lipid bilayer surrounding a microbody.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0060002	biolink:NamedThing	plus-end directed microfilament motor activity	A motor activity that generates movement along a microfilament towards the plus end, driven by ATP hydrolysis. The minus end of an actin filament is the end that does not preferentially add actin monomers.	tmpzr1t_l9r_go_relaxed.owl	plus-end directed actin-filament motor activity|plus-end directed actin filament motor activity|barbed-end directed actin-filament motor activity													molecular_function											owl:Class	
GO:0030949	biolink:NamedThing	positive regulation of vascular endothelial growth factor receptor signaling pathway	Any process that activates or increases the frequency, rate or extent of vascular endothelial growth factor receptor signaling pathway activity.	tmpzr1t_l9r_go_relaxed.owl	upregulation of vascular endothelial growth factor receptor signaling pathway|up-regulation of vascular endothelial growth factor receptor signaling pathway|positive regulation of VEGF receptor signalling pathway|up regulation of vascular endothelial growth factor receptor signaling pathway|positive regulation of vascular endothelial growth factor receptor signalling pathway|stimulation of vascular endothelial growth factor receptor signaling pathway|activation of vascular endothelial growth factor receptor signaling pathway|positive regulation of VEGF receptor signaling pathway													biological_process											owl:Class	
GO:0030947	biolink:NamedThing	regulation of vascular endothelial growth factor receptor signaling pathway	Any process that modulates the frequency, rate or extent of vascular endothelial growth factor receptor signaling pathway activity.	tmpzr1t_l9r_go_relaxed.owl	regulation of VEGF receptor signaling pathway|regulation of VEGF receptor signalling pathway|regulation of vascular endothelial growth factor receptor signalling pathway													biological_process											owl:Class	
GO:0050416	biolink:NamedThing	formimidoylglutamate deiminase activity	Catalysis of the reaction: N-formimidoyl-L-glutamate + H2O = N-formyl-L-glutamate + NH3.	tmpzr1t_l9r_go_relaxed.owl	N-formimidoyl-L-glutamate iminohydrolase activity|formiminoglutamate deiminase activity|formiminoglutamic iminohydrolase activity				MetaCyc:FORMIMINOGLUTAMATE-DEIMINASE-RXN|EC:3.5.3.13|RHEA:22832									molecular_function											owl:Class	
GO:0110031	biolink:NamedThing	negative regulation of G2/MI transition of meiotic cell cycle	Any signalling pathway that decreases or inhibits the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to MI phase of the meiotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl								kmv	2017-07-12T20:36:35Z					biological_process											owl:Class	
GO:0009585	biolink:NamedThing	red, far-red light phototransduction	The sequence of reactions within a cell required to convert absorbed photons from red or far-red light into a molecular signal; the red, far-red light range is defined as having a wavelength within the range 660-730 nm.	tmpzr1t_l9r_go_relaxed.owl	red-sensitive opsin|phytochrome signaling pathway													biological_process											owl:Class	
GO:0007602	biolink:NamedThing	phototransduction	The sequence of reactions within a cell required to convert absorbed photons into a molecular signal.	tmpzr1t_l9r_go_relaxed.owl	phototransduction, visible light, light adaptation|opsin|phototrophin mediated phototransduction				Wikipedia:Visual_phototransduction									biological_process											owl:Class	
GO:0042304	biolink:NamedThing	regulation of fatty acid biosynthetic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of fatty acids, any of the aliphatic monocarboxylic acids that can be liberated by hydrolysis from naturally occurring fats and oils.	tmpzr1t_l9r_go_relaxed.owl	regulation of fatty acid synthesis|regulation of fatty acid formation|regulation of fatty acid biosynthesis|regulation of fatty acid anabolism													biological_process											owl:Class	
GO:2000770	biolink:NamedThing	negative regulation of establishment or maintenance of cell polarity regulating cell shape	Any process that stops, prevents or reduces the frequency, rate or extent of establishment or maintenance of cell polarity regulating cell shape.	tmpzr1t_l9r_go_relaxed.owl								mah	2011-06-22T01:56:53Z					biological_process											owl:Class	
GO:2000769	biolink:NamedThing	regulation of establishment or maintenance of cell polarity regulating cell shape	Any process that modulates the frequency, rate or extent of establishment or maintenance of cell polarity regulating cell shape.	tmpzr1t_l9r_go_relaxed.owl								mah	2011-06-22T01:56:49Z					biological_process											owl:Class	
GO:1903003	biolink:NamedThing	positive regulation of protein deubiquitination	Any process that activates or increases the frequency, rate or extent of protein deubiquitination.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of protein deubiquitylation|up-regulation of protein deubiquitylation|up-regulation of protein deubiquitinylation|upregulation of protein deubiquitylation|up regulation of protein deubiquitylation|activation of deubiquitination|up regulation of protein deubiquitination|up-regulation of protein deubiquitination|up-regulation of deubiquitination|positive regulation of protein deubiquitinylation|activation of protein deubiquitinylation|up regulation of protein deubiquitinylation|up regulation of deubiquitination|positive regulation of deubiquitination|upregulation of protein deubiquitination|activation of protein deubiquitylation|upregulation of deubiquitination|activation of protein deubiquitination|upregulation of protein deubiquitinylation							bf	2014-05-12T15:39:10Z					biological_process											owl:Class	
GO:0005153	biolink:NamedThing	interleukin-8 receptor binding	Binding to an interleukin-8 receptor.	tmpzr1t_l9r_go_relaxed.owl	IL-8|interleukin-8 receptor ligand													molecular_function											owl:Class	
GO:0031003	biolink:NamedThing	actin tubule	A cellular structure, approximately 13 nm in diameter, consisting of three actin filaments bundled together.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0040010	biolink:NamedThing	positive regulation of growth rate	Any process that increases the rate of growth of all or part of an organism.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of growth rate|activation of growth rate|stimulation of growth rate|upregulation of growth rate|up regulation of growth rate					Note that this term and its definition depart from the usual conventions for GO 'regulation' process terms; regulation of rate is not usually distinguished from regulation of extent or frequency, but it makes sense to do so for growth regulation.								biological_process											owl:Class	
GO:1901751	biolink:NamedThing	leukotriene A4 metabolic process	The chemical reactions and pathways involving leukotriene A4.	tmpzr1t_l9r_go_relaxed.owl	leukotriene A4 metabolism							yaf	2013-01-14T11:04:56Z					biological_process											owl:Class	
GO:0050180	biolink:NamedThing	phloretin hydrolase activity	Catalysis of the reaction: H(2)O + phloretin = H(+) + phloretate + phloroglucinol.	tmpzr1t_l9r_go_relaxed.owl	lactase-phlorizin hydrolase|2',4,4',6'-tetrahydroxydehydrochalcone 1,3,5-trihydroxybenzenehydrolase activity				EC:3.7.1.4|RHEA:23396|KEGG_REACTION:R02901|MetaCyc:PHLORETIN-HYDROLASE-RXN									molecular_function											owl:Class	
GO:0008608	biolink:NamedThing	attachment of spindle microtubules to kinetochore	The process in which spindle microtubules become physically associated with the proteins making up the kinetochore complex.	tmpzr1t_l9r_go_relaxed.owl	kinetochore-microtubule interaction|amphotelic attachment|microtubule anchoring at kinetochore|bipolar attachment|microtubule capture|microtubule and kinetochore interaction|spindle-chromosome interaction|kinetochore microtubule interaction|attachment of spindle microtubules to chromosome|spindle kinetochore attachment|kinetochore-microtubule attachment|microtubule and chromosome interaction|spindle chromosome attachment					This class covers all attachments of spindle microtubules to the kinetochore, including the many incorrect attachments which initially form and are later corrected to stable attachments with the correct orientation for segregation to proceed (sister chromatid biorientation).						GO:0051313		biological_process											owl:Class	
GO:0009992	biolink:NamedThing	cellular water homeostasis	Any process involved in the maintenance of an internal steady state of water within a cell.	tmpzr1t_l9r_go_relaxed.owl	cellular osmoregulation													biological_process											owl:Class	
GO:0070229	biolink:NamedThing	negative regulation of lymphocyte apoptotic process	Any process that stops, prevents, or reduces the frequency, rate or extent of lymphocyte death by apoptotic process.	tmpzr1t_l9r_go_relaxed.owl	inhibition of lymphocyte apoptosis|down-regulation of lymphocyte apoptosis|down regulation of lymphocyte apoptosis|negative regulation of lymphocyte apoptosis|downregulation of lymphocyte apoptosis					Note that a lymphocyte is a cell of the B cell, T cell, or natural killer cell lineage (CL:0000542).								biological_process											owl:Class	
GO:1902613	biolink:NamedThing	negative regulation of anti-Mullerian hormone signaling pathway	Any process that stops, prevents or reduces the frequency, rate or extent of anti-Mullerian hormone signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	inhibition of anti-Mullerian hormone signaling pathway|down-regulation of anti-Mullerian hormone signaling pathway|down regulation of anti-Mullerian hormone signaling pathway|downregulation of anti-Mullerian hormone signaling pathway							hjd	2014-01-09T15:39:39Z					biological_process											owl:Class	
GO:0061290	biolink:NamedThing	canonical Wnt signaling pathway involved in metanephric kidney development	The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes that contribute to the progression of the metanephric kidney over time. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes.	tmpzr1t_l9r_go_relaxed.owl	canonical Wnt receptor signalling pathway involved in metanephric kidney development|canonical Wnt receptor signaling pathway involved in metanephric kidney development|canonical Wnt-activated signaling pathway involved in metanephric kidney development							dph	2010-09-03T12:06:10Z					biological_process											owl:Class	
GO:0009199	biolink:NamedThing	ribonucleoside triphosphate metabolic process	The chemical reactions and pathways involving a ribonucleoside triphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with triphosphate on the sugar.	tmpzr1t_l9r_go_relaxed.owl	ribonucleoside triphosphate metabolism													biological_process											owl:Class	
GO:0072724	biolink:NamedThing	response to 4-nitroquinoline N-oxide	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 4-nitroquinoline N-oxide stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2012-05-31T11:00:37Z					biological_process											owl:Class	
GO:0034344	biolink:NamedThing	regulation of type III interferon production	Any process that modulates the frequency, rate, or extent of type III interferon production. Interferon lambda is the only member of the type III interferon found so far.	tmpzr1t_l9r_go_relaxed.owl	regulation of type III IFN production					Note that IL-28A, IL-28B, and IL-29 are types of interferon-lambda.								biological_process											owl:Class	
GO:0032425	biolink:NamedThing	positive regulation of mismatch repair	Any process that activates or increases the frequency, rate or extent of mismatch repair.	tmpzr1t_l9r_go_relaxed.owl	activation of mismatch repair|up-regulation of mismatch repair|upregulation of mismatch repair|up regulation of mismatch repair|stimulation of mismatch repair													biological_process											owl:Class	
GO:0102865	biolink:NamedThing	delta6-acyl-lipid desaturase activity	Catalysis of the reaction: a gamma-linolenoyl-[glycerolipid] + 2 ferrocytochrome b5 + O(2) + 2 H(+) <=> a (9Z,12Z)-octadeca-9,12-dien-6-ynoyl-[glycerolipid] + 2 ferricytochrome b5 + 2 H(2)O.	tmpzr1t_l9r_go_relaxed.owl					EC:1.14.19.38|RHEA:46536|MetaCyc:RXN-8343									molecular_function											owl:Class	
GO:0071799	biolink:NamedThing	cellular response to prostaglandin D stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin D stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-09-03T10:48:35Z					biological_process											owl:Class	
GO:0071379	biolink:NamedThing	cellular response to prostaglandin stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-12-11T03:33:52Z					biological_process											owl:Class	
GO:0034975	biolink:NamedThing	protein folding in endoplasmic reticulum	A protein folding process that takes place in the endoplasmic reticulum (ER). Secreted, plasma membrane and organelle proteins are folded in the ER, assisted by chaperones and foldases (protein disulphide isomerases), and additional factors required for optimal folding (ATP, Ca2+ and an oxidizing environment to allow disulfide bond formation).	tmpzr1t_l9r_go_relaxed.owl	oxidative protein folding|protein folding in ER													biological_process											owl:Class	
GO:0062084	biolink:NamedThing	regulation of capsule polysaccharide biosynthetic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of polysaccharides that make up the capsule, a protective structure surrounding some species of bacteria and fungi.	tmpzr1t_l9r_go_relaxed.owl								dph	2018-10-31T15:58:08Z					biological_process											owl:Class	
GO:1901913	biolink:NamedThing	regulation of capsule organization	Any process that modulates the frequency, rate or extent of capsule organization.	tmpzr1t_l9r_go_relaxed.owl	regulation of capsule organization and biogenesis|regulation of capsule organisation							di	2013-02-14T06:19:03Z					biological_process											owl:Class	
GO:1904369	biolink:NamedThing	positive regulation of sclerenchyma cell differentiation	Any process that activates or increases the frequency, rate or extent of sclerenchyma cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	up regulation of sclerenchyma cell differentiation|upregulation of sclerenchyma cell differentiation|up-regulation of sclerenchyma cell differentiation							tb	2015-06-17T19:53:06Z					biological_process											owl:Class	
GO:0051956	biolink:NamedThing	negative regulation of amino acid transport	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of amino acid transport|down regulation of amino acid transport|downregulation of amino acid transport|negative regulation of amino acid transmembrane transport|inhibition of amino acid transport													biological_process											owl:Class	
GO:0035876	biolink:NamedThing	maintenance of meiotic sister chromatid cohesion, arms	The process in which the association between sister chromatids of a replicated chromosome along the length of the chromosome arms, is maintained as chromosomes condense, attach to the spindle in a bipolar orientation, and congress to the metaphase plate during a meiotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl	maintenance of sister chromatin cohesion along arms at meiosis I|maintenance of meiotic sister chromatin cohesion along arms							bf	2011-05-31T09:37:53Z					biological_process											owl:Class	
GO:0033308	biolink:NamedThing	hydroxyectoine transport	The directed movement of hydroxyectoine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0015697	biolink:NamedThing	quaternary ammonium group transport	The directed movement into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore of quaternary ammonium compounds, any compound that can be regarded as derived from ammonium hydroxide or an ammonium salt by replacement of all four hydrogen atoms of the NH4+ ion by organic groups.	tmpzr1t_l9r_go_relaxed.owl	quaternary ammonium compound transport|quaternary amine transport											GO:0015845		biological_process											owl:Class	
GO:0099154	biolink:NamedThing	serotonergic synapse	A synapse that uses serotonin as a neurotransmitter.	tmpzr1t_l9r_go_relaxed.owl								dos	2017-07-05T14:22:05Z					cellular_component											owl:Class	
GO:0010506	biolink:NamedThing	regulation of autophagy	Any process that modulates the frequency, rate or extent of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0062000	biolink:NamedThing	positive regulation of cardiac endothelial to mesenchymal transition	Any process that activates or increases the frequency, rate or extent of cardiac endothelial to mesenchymal trnasition.	tmpzr1t_l9r_go_relaxed.owl								dph	2018-02-16T16:31:06Z					biological_process											owl:Class	
GO:0061999	biolink:NamedThing	regulation of cardiac endothelial to mesenchymal transition	Any process that modulates the frequency, rate or extent of cardiac endothelial to mesenchymal transition.	tmpzr1t_l9r_go_relaxed.owl								dph	2018-02-16T16:26:51Z					biological_process											owl:Class	
GO:0018669	biolink:NamedThing	3-hydroxybenzoate 6-monooxygenase activity	Catalysis of the reaction: 3-hydroxybenzoate + H(+) + NADH + O(2) = 2,5-dihydroxybenzoate + H(2)O + NAD(+).	tmpzr1t_l9r_go_relaxed.owl	3-hydroxybenzoate,NADH:oxygen oxidoreductase (6-hydroxylating)|m-hydroxybenzoate 6-hydroxylase activity|3-hydroxybenzoate 6-hydroxylase activity|3-hydroxybenzoic acid-6-hydroxylase activity				EC:1.14.13.24|UM-BBD_reactionID:r0402|KEGG_REACTION:R02589|MetaCyc:3-HYDROXYBENZOATE-6-MONOOXYGENASE-RXN|RHEA:22692									molecular_function											owl:Class	
GO:0035261	biolink:NamedThing	external genitalia morphogenesis	The process in which the anatomical structures of the external genitalia are generated and organized. The external genitalia are the outer sex organs, such as the penis or vulva in mammals.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0035112	biolink:NamedThing	genitalia morphogenesis	The process in which the anatomical structures of genitalia are generated and organized. The genitalia are the organs of reproduction or generation, external and internal.	tmpzr1t_l9r_go_relaxed.owl	genital morphogenesis													biological_process											owl:Class	
GO:0097669	biolink:NamedThing	SCF-Skp2 ubiquitin ligase complex	An SCF ubiquitin ligase complex in which the F-box protein is Skp2 in S. cerevisiae.	tmpzr1t_l9r_go_relaxed.owl								pr	2014-10-06T10:28:52Z					cellular_component											owl:Class	
GO:0062141	biolink:NamedThing	nuclear exosome targeting complex	A protein-containing complex that functions with the RNA exosome and contributes to the degradation of abberant transcripts.	tmpzr1t_l9r_go_relaxed.owl	NEXT complex							dph	2019-08-29T14:46:59Z					cellular_component											owl:Class	
GO:0002293	biolink:NamedThing	alpha-beta T cell differentiation involved in immune response	The process in which an antigenically naive alpha-beta T cell acquires the specialized features of an effector, regulatory, or memory T cell during an immune response. Effector T cells include cells which provide T cell help or exhibit cytotoxicity towards other cells.	tmpzr1t_l9r_go_relaxed.owl	alpha-beta T-lymphocyte differentiation during immune response|alpha-beta T cell differentiation during immune response|alpha-beta T-cell differentiation during immune response|alpha-beta T cell development involved in immune response|alpha-beta T lymphocyte differentiation during immune response					Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.								biological_process											owl:Class	
GO:0046632	biolink:NamedThing	alpha-beta T cell differentiation	The process in which a precursor cell type acquires the specialized features of an alpha-beta T cell. An alpha-beta T cell is a T cell that expresses an alpha-beta T cell receptor complex.	tmpzr1t_l9r_go_relaxed.owl	alpha-beta T-cell differentiation|alpha-beta T-lymphocyte differentiation|alpha-beta T cell development|alpha-beta T lymphocyte differentiation					Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.								biological_process											owl:Class	
GO:0042644	biolink:NamedThing	chloroplast nucleoid	The region of a chloroplast to which the DNA is confined.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0019512	biolink:NamedThing	lactose catabolic process via tagatose-6-phosphate	The chemical reactions and pathways resulting in the breakdown of lactose, via the intermediate tagatose-6-phosphate.	tmpzr1t_l9r_go_relaxed.owl	lactose breakdown via tagatose-6-phosphate|lactose degradation via tagatose-6-phosphate				MetaCyc:LACTOSECAT-PWY									biological_process											owl:Class	
GO:0005990	biolink:NamedThing	lactose catabolic process	The chemical reactions and pathways resulting in the breakdown of lactose, the disaccharide galactopyranosyl-glucose.	tmpzr1t_l9r_go_relaxed.owl	lactose degradation|lactose breakdown|lactose catabolism													biological_process											owl:Class	
GO:0002483	biolink:NamedThing	antigen processing and presentation of endogenous peptide antigen	The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC protein complex. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell.	tmpzr1t_l9r_go_relaxed.owl	endogenous peptide antigen processing and presentation													biological_process											owl:Class	
GO:0019883	biolink:NamedThing	antigen processing and presentation of endogenous antigen	The process in which an antigen-presenting cell expresses antigen (peptide or lipid) of endogenous origin on its cell surface in association with an MHC protein complex.	tmpzr1t_l9r_go_relaxed.owl	antigen presentation, endogenous antigen													biological_process											owl:Class	
GO:0060587	biolink:NamedThing	regulation of lipoprotein lipid oxidation	Any process that modulates the rate, frequency or extent of lipoprotein lipid oxidation. Lipoprotein lipid oxidation is the modification of a lipoprotein by oxidation of the lipid group.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-05-08T02:27:02Z					biological_process											owl:Class	
GO:0046546	biolink:NamedThing	development of primary male sexual characteristics	The process whose specific outcome is the progression of the primary male sexual characteristics over time, from their formation to the mature structures. The primary male sexual characteristics are the testes, and they develop in response to sex hormone secretion.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0045137	biolink:NamedThing	development of primary sexual characteristics	The process whose specific outcome is the progression of the primary sexual characteristics over time, from their formation to the mature structures. The primary sexual characteristics are the testes in males and the ovaries in females and they develop in response to sex hormone secretion.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0060345	biolink:NamedThing	spleen trabecula formation	The process of creating a trabecula in the spleen. A trabecula is a tissue element in the form of a small beam, strut or rod.	tmpzr1t_l9r_go_relaxed.owl	spleen trabecula biogenesis|spleen trabeculation													biological_process											owl:Class	
GO:0060343	biolink:NamedThing	trabecula formation	The process of creating a trabecula in an organ. A trabecula is a small, often microscopic, tissue element in the form of a small beam, strut or rod, which generally has a mechanical function. Trabecula are usually but not necessarily, composed of dense collagenous tissue.	tmpzr1t_l9r_go_relaxed.owl	trabecula biogenesis|trabeculation													biological_process											owl:Class	
GO:0007585	biolink:NamedThing	respiratory gaseous exchange by respiratory system	The process of gaseous exchange between an organism and its environment. In plants, microorganisms, and many small animals, air or water makes direct contact with the organism's cells or tissue fluids, and the processes of diffusion supply the organism with dioxygen (O2) and remove carbon dioxide (CO2). In larger animals the efficiency of gaseous exchange is improved by specialized respiratory organs, such as lungs and gills, which are ventilated by breathing mechanisms.	tmpzr1t_l9r_go_relaxed.owl	respiration|breathing													biological_process											owl:Class	
GO:0019183	biolink:NamedThing	histamine-gated chloride channel complex	A protein complex that forms a transmembrane channel through which chloride ions may pass in response to histamine binding to the channel complex or one of its constituent parts.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0034707	biolink:NamedThing	chloride channel complex	An ion channel complex through which chloride ions pass.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0042547	biolink:NamedThing	cell wall modification involved in multidimensional cell growth	The series of events resulting in chemical or structural changes to existing cell walls and contribute to multidimensional cell growth.	tmpzr1t_l9r_go_relaxed.owl	cell wall modification during cell expansion|cell wall modification during multidimensional cell growth													biological_process											owl:Class	
GO:0001944	biolink:NamedThing	vasculature development	The process whose specific outcome is the progression of the vasculature over time, from its formation to the mature structure. The vasculature is an interconnected tubular multi-tissue structure that contains fluid that is actively transported around the organism.	tmpzr1t_l9r_go_relaxed.owl	vascular system development													biological_process											owl:Class	
GO:2000030	biolink:NamedThing	regulation of response to red or far red light	Any process that modulates the frequency, rate or extent of response to red or far red light.	tmpzr1t_l9r_go_relaxed.owl								tb	2010-08-05T11:30:10Z					biological_process											owl:Class	
GO:0061475	biolink:NamedThing	cytosolic valyl-tRNA aminoacylation	The process of coupling valine to valyl-tRNA in the cytosol, catalyzed by valyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.	tmpzr1t_l9r_go_relaxed.owl								dph	2012-11-06T12:29:42Z					biological_process											owl:Class	
GO:0006438	biolink:NamedThing	valyl-tRNA aminoacylation	The process of coupling valine to valyl-tRNA, catalyzed by valyl-tRNA synthetase. The valyl-tRNA synthetase is a  class-I synthetase. The activated amino acid is transferred to the 2'-OH group of a valine-accetping tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0006198	biolink:NamedThing	cAMP catabolic process	The chemical reactions and pathways resulting in the breakdown of the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate).	tmpzr1t_l9r_go_relaxed.owl	3',5'-cAMP catabolism|cyclic AMP catabolism|cyclic AMP catabolic process|3',5' cAMP catabolic process|cAMP degradation|3',5'-cAMP catabolic process|cAMP breakdown|adenosine 3',5'-cyclophosphate catabolic process|cAMP catabolism|adenosine 3',5'-cyclophosphate catabolism|3',5' cAMP catabolism													biological_process											owl:Class	
GO:0009214	biolink:NamedThing	cyclic nucleotide catabolic process	The chemical reactions and pathways resulting in the breakdown of a cyclic nucleotide, a nucleotide in which the phosphate group is in diester linkage to two positions on the sugar residue.	tmpzr1t_l9r_go_relaxed.owl	cyclic nucleotide catabolism|cyclic nucleotide breakdown|cyclic nucleotide degradation													biological_process											owl:Class	
GO:0150179	biolink:NamedThing	positive regulation of phosphatidylserine metabolic process	Any process that activates or increases the frequency, rate or extent of phosphatidylserine metabolic process.	tmpzr1t_l9r_go_relaxed.owl								bc	2020-01-21T14:05:52Z					biological_process											owl:Class	
GO:0150178	biolink:NamedThing	regulation of phosphatidylserine metabolic process	Any process that modulates the frequency, rate or extent of phosphatidylserine metabolic process.	tmpzr1t_l9r_go_relaxed.owl								bc	2020-01-21T14:05:21Z					biological_process											owl:Class	
GO:0045491	biolink:NamedThing	xylan metabolic process	The chemical reactions and pathways involving xylan, a polymer containing a beta-1,4-linked D-xylose backbone.	tmpzr1t_l9r_go_relaxed.owl	xylan metabolism													biological_process											owl:Class	
GO:0043478	biolink:NamedThing	pigment accumulation in response to UV light	The aggregation of coloring matter in a particular location in an organism, tissue or cell, occurring in response to a UV light stimulus.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0043476	biolink:NamedThing	pigment accumulation	The aggregation of coloring matter in a particular location in an organism, tissue or cell, occurring in response to some external stimulus.	tmpzr1t_l9r_go_relaxed.owl	pigment accumulation in response to external stimulus													biological_process											owl:Class	
GO:2000354	biolink:NamedThing	regulation of ovarian follicle development	Any process that modulates the frequency, rate or extent of ovarian follicle development.	tmpzr1t_l9r_go_relaxed.owl	regulation of follicular phase							yaf	2011-02-03T02:01:28Z					biological_process											owl:Class	
GO:0009107	biolink:NamedThing	lipoate biosynthetic process	The chemical reactions and pathways resulting in the formation of lipoate, 1,2-dithiolane-3-pentanoate, the anion derived from lipoic acid.	tmpzr1t_l9r_go_relaxed.owl	lipoic acid formation|lipoate synthesis|lipoic acid biosynthetic process|lipoate biosynthesis|lipoic acid biosynthesis|lipoic acid anabolism|lipoate formation|lipoate anabolism|lipoic acid synthesis											GO:0009105		biological_process											owl:Class	
GO:0002834	biolink:NamedThing	regulation of response to tumor cell	Any process that modulates the frequency, rate, or extent of a response to tumor cell.	tmpzr1t_l9r_go_relaxed.owl	regulation of response to tumour cell													biological_process											owl:Class	
GO:0051270	biolink:NamedThing	regulation of cellular component movement	Any process that modulates the frequency, rate or extent of the movement of a cellular component.	tmpzr1t_l9r_go_relaxed.owl	regulation of cell movement|regulation of cellular component motion													biological_process											owl:Class	
GO:0039526	biolink:NamedThing	modulation by virus of host apoptotic process	Any process in which a virus modulates the frequency, rate or extent of apoptosis of infected host cells.	tmpzr1t_l9r_go_relaxed.owl	modulation by virus of host apoptosis|regulation by virus of host apoptosis|modulation of host cell apoptosis by virus				VZ:1581			bf	2011-06-22T05:22:53Z					biological_process											owl:Class	
GO:1905772	biolink:NamedThing	positive regulation of mesodermal cell differentiation	Any process that activates or increases the frequency, rate or extent of mesodermal cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	upregulation of mesoderm cell differentiation|up-regulation of mesoderm cell differentiation|up regulation of mesoderm cell differentiation|activation of mesoderm cell differentiation|upregulation of mesodermal cell differentiation|up-regulation of mesodermal cell differentiation|positive regulation of mesoderm cell differentiation|activation of mesodermal cell differentiation|up regulation of mesodermal cell differentiation							rph	2016-12-21T12:44:32Z					biological_process											owl:Class	
GO:1905770	biolink:NamedThing	regulation of mesodermal cell differentiation	Any process that modulates the frequency, rate or extent of mesodermal cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	regulation of mesoderm cell differentiation							rph	2016-12-21T12:44:13Z					biological_process											owl:Class	
GO:0030374	biolink:NamedThing	nuclear receptor coactivator activity	A transcription coactivator activity that activates or increases the transcription of specific gene sets via binding to a DNA-bound nuclear receptor, either on its own or as part of a complex. Coactivators often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second class remodels the conformation of chromatin in an ATP-dependent fashion. A third class modulates interactions of DNA-bound DNA-binding transcription factors with other transcription coregulators. A fourth class of coactivator activity is the bridging of a DNA-binding transcription factor to the general (basal) transcription machinery. The Mediator complex, which bridges sequence-specific DNA binding transcription factors and RNA polymerase, is also a transcription coactivator.	tmpzr1t_l9r_go_relaxed.owl	ligand-activated RNA polymerase II transcription factor binding transcription factor activity|transcription factor activity, ligand-activated RNA polymerase II transcription factor binding|ligand-dependent nuclear receptor transcription co-activator activity|nuclear receptor transcription coactivator activity|ligand-dependent nuclear receptor transcription coactivator activity	https://github.com/geneontology/go-ontology/issues/20253|https://github.com/geneontology/go-ontology/issues/20464				For usage guidance, see comment in GO:0003712 ; transcription coregulator activity.		bf	2011-11-29T01:53:30Z			GO:0038049		molecular_function											owl:Class	
GO:0003713	biolink:NamedThing	transcription coactivator activity	A transcription coregulator activity that activates or increases the transcription of specific gene sets via binding to a DNA-bound DNA-binding transcription factor, either on its own or as part of a complex. Coactivators often act by altering chromatin structure and modifications. For example, one class of transcription coactivators modifies chromatin structure through covalent modification of histones. A second class remodels the conformation of chromatin in an ATP-dependent fashion. A third class modulates interactions of DNA-bound DNA-binding transcription factors with other transcription coregulators. A fourth class of coactivator activity is the bridging of a DNA-binding transcription factor to the general (basal) transcription machinery. The Mediator complex, which bridges sequence-specific DNA binding transcription factors and RNA polymerase, is also a transcription coactivator.	tmpzr1t_l9r_go_relaxed.owl	RNA polymerase II transcription coactivator activity|transcription co-activator activity|RNA polymerase II transcription co-activator activity|RNA polymerase II transcription mediator activity	https://github.com/geneontology/go-ontology/issues/20253|https://github.com/geneontology/go-ontology/issues/20464|https://github.com/geneontology/go-ontology/issues/15998|https://github.com/geneontology/go-ontology/issues/15665				For usage guidance, see comment in GO:0003712 ; transcription coregulator activity.		krc	2010-11-24T03:08:19Z			GO:0001105		molecular_function											owl:Class	
GO:0045981	biolink:NamedThing	positive regulation of nucleotide metabolic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving nucleotides.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of nucleotide metabolism|up regulation of nucleotide metabolic process|activation of nucleotide metabolic process|stimulation of nucleotide metabolic process|upregulation of nucleotide metabolic process|up-regulation of nucleotide metabolic process													biological_process											owl:Class	
GO:0060812	biolink:NamedThing	orthodenticle mRNA localization	Any process in which orthodenticle mRNA is transported to and maintained in the oocyte and/or syncytial embryo as part of the process that will specify the anterior/posterior axis.	tmpzr1t_l9r_go_relaxed.owl	orthodenticle mRNA localisation							dph	2009-08-07T09:39:01Z					biological_process											owl:Class	
GO:0060811	biolink:NamedThing	intracellular mRNA localization involved in anterior/posterior axis specification	Any process in which mRNA is transported to, or maintained in, a specific location within the oocyte and/or syncytial embryo that contributes to the specification of the anterior/posterior axis.	tmpzr1t_l9r_go_relaxed.owl	intracellular mRNA localisation involved in anterior/posterior axis specification							dph	2009-08-07T09:26:22Z					biological_process											owl:Class	
GO:0044667	biolink:NamedThing	(R)-carnitine:4-(trimethylammonio)butanoate antiporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: (R)-carnitine(out) + 4-(trimethylammonio)butanoate(in) = (R)-carnitine(in) + 4-(trimethylammonio)butanoate(out).	tmpzr1t_l9r_go_relaxed.owl	(R)-carnitine:gamma-butyrobetaine antiporter activity|L-carnitine:4-(trimethylammonio)butanoate antiporter activity|L-carnitine:gamma-butyrobetaine antiporter activity				RHEA:29427			jl	2012-08-08T11:17:12Z					molecular_function											owl:Class	
GO:1901236	biolink:NamedThing	4-(trimethylammonio)butanoate transmembrane transporter activity	Enables the transfer of 4-(trimethylammonio)butanoate from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl					RHEA:32835			jl	2012-08-07T14:46:52Z					molecular_function											owl:Class	
GO:0075276	biolink:NamedThing	regulation of telium development	Any process that modulates the frequency, rate or extent of telium development, a process that leads to the formation of a teliospore-bearing sorus of the rust fungi.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0018901	biolink:NamedThing	2,4-dichlorophenoxyacetic acid metabolic process	The chemical reactions and pathways involving 2,4-dichlorophenoxyacetic acid, a chlorinated phenoxy compound which functions as a systemic herbicide and is used to control many types of broadleaf weeds.	tmpzr1t_l9r_go_relaxed.owl	2,4-D metabolic process|2,4-dichlorophenoxyacetic acid metabolism|2,4-D metabolism				UM-BBD_pathwayID:2,4-d									biological_process											owl:Class	
GO:0047636	biolink:NamedThing	alanopine dehydrogenase activity	Catalysis of the reaction: 2,2'-iminodipropanoate + H(2)O + NAD(+) = L-alanine + H(+) + NADH + pyruvate.	tmpzr1t_l9r_go_relaxed.owl	ADH|alanopine: NAD oxidoreductase activity|2,2'-iminodipropanoate:NAD+ oxidoreductase (L-alanine-forming)|alanopine[meso-N-(1-carboxyethyl)-alanine]dehydrogenase activity|meso-N-(1-carboxyethyl)-alanine:NAD+ oxidoreductase activity|alanopine:NAD oxidoreductase activity|ALPDH				KEGG_REACTION:R00398|EC:1.5.1.17|MetaCyc:ALANOPINE-DEHYDROGENASE-RXN|RHEA:17589									molecular_function											owl:Class	
GO:0045200	biolink:NamedThing	establishment of neuroblast polarity	The specification and formation of the apicobasal polarity of a neuroblast cell, a progenitor of the central nervous system.	tmpzr1t_l9r_go_relaxed.owl	establishment of neuroblast cell polarity											GO:0043343|GO:0043340		biological_process											owl:Class	
GO:1905795	biolink:NamedThing	cellular response to puromycin	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a puromycin stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to 3'-deoxy-N,N-dimethyl-3'-(O-methyl-L-tyrosinamido)adenosine							sl	2017-01-10T21:13:28Z					biological_process											owl:Class	
GO:0071577	biolink:NamedThing	zinc ion transmembrane transport	A process in which a zinc II ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	zinc transmembrane transport|zinc ion membrane transport|zinc II ion transmembrane transport					Note that this term is not intended for use in annotating lateral movement within membranes.		mah	2010-01-28T02:17:12Z					biological_process											owl:Class	
GO:0006829	biolink:NamedThing	zinc ion transport	The directed movement of zinc (Zn II) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	zinc II ion transport|zinc transport													biological_process											owl:Class	
GO:0120267	biolink:NamedThing	pellicular membrane	The portion of the plasma membrane surrounding the pellicle, a structure enclosing some parasite cells such as certain apicomplexa and Euglenozoa. These membranes are associated with an infrastructure of microtubules, microfilaments, and other organelles.	tmpzr1t_l9r_go_relaxed.owl	pellicular plasma membrane|pellicle membrane	https://github.com/geneontology/go-ontology/issues/20034				This sub-domain of the plasma membrane excludes the ciliary and ciliary pocket membranes.		krc	2020-09-29T21:08:28Z					cellular_component											owl:Class	
GO:0005845	biolink:NamedThing	mRNA cap binding complex	Any protein complex that binds to an mRNA cap at any time in the lifetime of the mRNA.	tmpzr1t_l9r_go_relaxed.owl	mRNA cap complex													cellular_component											owl:Class	
GO:0034518	biolink:NamedThing	RNA cap binding complex	Any protein complex that binds to a specialized RNA cap structure at any time in the lifetime of the RNA.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0061954	biolink:NamedThing	positive regulation of actin filament polymerization involved in sperm capacitation	Any process that icreases the rate or extent of actin polymerization as part of sperm capacitation. This process prevents a spontaneous acrosome reaction.	tmpzr1t_l9r_go_relaxed.owl								dph	2017-11-10T19:40:00Z					biological_process											owl:Class	
GO:0042593	biolink:NamedThing	glucose homeostasis	Any process involved in the maintenance of an internal steady state of glucose within an organism or cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0033500	biolink:NamedThing	carbohydrate homeostasis	A homeostatic process involved in the maintenance of an internal steady state of a carbohydrate within an organism or cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0061528	biolink:NamedThing	aspartate secretion	The regulated release of aspartate by a cell.	tmpzr1t_l9r_go_relaxed.owl								dph	2013-06-21T15:45:37Z					biological_process											owl:Class	
GO:0008773	biolink:NamedThing	[protein-PII] uridylyltransferase activity	Catalysis of the reaction: UTP + (protein-PII) = diphosphate + uridylyl-(protein-PII).	tmpzr1t_l9r_go_relaxed.owl	protein-PII uridylyltransferase activity|UTP:protein-PII uridylyltransferase activity|uridyl removing enzyme|UTP:[protein-PII] uridylyltransferase activity|PII uridylyl-transferase activity|uridylyl removing enzyme activity				MetaCyc:URITRANS-RXN|RHEA:13673|EC:2.7.7.59									molecular_function											owl:Class	
GO:0009876	biolink:NamedThing	pollen adhesion	The process in which pollen deposited on the stigma adheres to cells of the stigma.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0098609	biolink:NamedThing	cell-cell adhesion	The attachment of one cell to another cell via adhesion molecules.	tmpzr1t_l9r_go_relaxed.owl	single organismal cell-cell adhesion							dos	2014-04-16T13:40:03Z			GO:0016337		biological_process											owl:Class	
GO:0072040	biolink:NamedThing	negative regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis	Any process that reduces the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of mesenchymal stem cell apoptosis involved in nephron morphogenesis|negative regulation of mesenchymal stem cell apoptotic process involved in nephron morphogenesis							mah	2010-01-25T03:09:30Z					biological_process											owl:Class	
GO:1904453	biolink:NamedThing	positive regulation of potassium:proton exchanging ATPase activity	Any process that activates or increases the frequency, rate or extent of hydrogen:potassium-exchanging ATPase activity.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of H+/K+-ATPase activity|upregulation of H+/K+-ATPase activity|positive regulation of H(+)/K(+)-exchanging ATPase activity|up-regulation of hydrogen:potassium exchanging ATPase activity|up regulation of ATP phosphohydrolase (H+/K+-exchanging)|up-regulation of H(+)/K(+)-ATPase activity|upregulation of H(+)/K(+)-exchanging ATPase activity|activation of gastric H+/K+ ATPase|upregulation of hydrogen:potassium-exchanging ATPase activity|up regulation of H,K-ATPase activity|upregulation of H,K-ATPase activity|activation of hydrogen/potassium-exchanging ATPase activity|up regulation of hydrogen:potassium-exchanging ATPase activity|positive regulation of hydrogen:potassium-exchanging ATPase activity|positive regulation of H+/K+-exchanging ATPase activity|upregulation of (K+ + H+)-ATPase activity|up regulation of H+/K+-ATPase activity|activation of ATP phosphohydrolase (H+/K+-exchanging)|up-regulation of H+-K+-ATPase activity|positive regulation of H,K-ATPase activity|activation of hydrogen:potassium-exchanging ATPase activity|up-regulation of H+/K+-exchanging ATPase activity|positive regulation of gastric H(+)/K(+) ATPase activity|up-regulation of H,K-ATPase activity|activation of H,K-ATPase activity|positive regulation of hydrogen/potassium-exchanging ATPase activity|up-regulation of gastric H(+)/K(+) ATPase activity|up regulation of H+-K+-ATPase activity|upregulation of H+-K+-ATPase activity|up regulation of (K+ + H+)-ATPase activity|activation of H(+)/K(+)-ATPase activity|up regulation of gastric H+/K+ ATPase|upregulation of hydrogen:potassium exchanging ATPase activity|activation of H(+)/K(+)-exchanging ATPase activity|positive regulation of H+/K+-ATPase activity|up-regulation of hydrogen/potassium-exchanging ATPase activity|activation of gastric H(+)/K(+) ATPase activity|up regulation of hydrogen:potassium exchanging ATPase activity|up regulation of hydrogen/potassium-exchanging ATPase activity|up regulation of H+/K+-exchanging ATPase activity|upregulation of hydrogen/potassium-exchanging ATPase activity|positive regulation of ATP phosphohydrolase (H+/K+-exchanging)|upregulation of gastric H+/K+ ATPase|up-regulation of gastric H+/K+ ATPase|upregulation of H+/K+-exchanging ATPase activity|positive regulation of H(+)/K(+)-ATPase activity|upregulation of ATP phosphohydrolase (H+/K+-exchanging)|activation of (K+ + H+)-ATPase activity|positive regulation of H+-K+-ATPase activity|up-regulation of hydrogen:potassium-exchanging ATPase activity|activation of H+-K+-ATPase activity|up regulation of H(+)/K(+)-ATPase activity|activation of H+/K+-ATPase activity|up-regulation of H(+)/K(+)-exchanging ATPase activity|up-regulation of ATP phosphohydrolase (H+/K+-exchanging)|positive regulation of gastric H+/K+ ATPase|upregulation of gastric H(+)/K(+) ATPase activity|up regulation of gastric H(+)/K(+) ATPase activity|positive regulation of (K+ + H+)-ATPase activity|activation of H+/K+-exchanging ATPase activity|positive regulation of hydrogen:potassium exchanging ATPase activity|up-regulation of (K+ + H+)-ATPase activity|upregulation of H(+)/K(+)-ATPase activity|up regulation of H(+)/K(+)-exchanging ATPase activity|activation of hydrogen:potassium exchanging ATPase activity							sl	2015-07-08T23:00:15Z					biological_process											owl:Class	
GO:0043651	biolink:NamedThing	linoleic acid metabolic process	The chemical reactions and pathways involving linoleic acid, an unsaturated omega-6 fatty acid that has the molecular formula C18H32O2.	tmpzr1t_l9r_go_relaxed.owl	linoleic acid metabolism				Wikipedia:Linoleic_acid									biological_process											owl:Class	
GO:1904694	biolink:NamedThing	negative regulation of vascular associated smooth muscle contraction	Any process that stops, prevents or reduces the frequency, rate or extent of vascular smooth muscle contraction.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of vascular smooth muscle contraction|down-regulation of vascular smooth muscle contraction|downregulation of vascular smooth muscle contraction|down regulation of vascular smooth muscle contraction|inhibition of vascular smooth muscle contraction							rph	2015-09-29T13:39:08Z					biological_process											owl:Class	
GO:0043486	biolink:NamedThing	histone exchange	The replacement, within chromatin, of resident histones or histone subunits with alternative, sometimes variant, histones or subunits.	tmpzr1t_l9r_go_relaxed.owl	histone replacement|histone chaperone					Note that this term also includes the exchange of sperm-specific histones or protamines with histones, occurring during spermatogenesis and fertilization.								biological_process											owl:Class	
GO:0036156	biolink:NamedThing	inner dynein arm	Inner arm structure present on the outer doublet microtubules of ciliary and flagellar axonemes. The structure of inner dynein arms is complex and may vary within the axoneme. Inner dynein arms are heteromeric, comprising 8 different heavy chains and various subunits. Inner and outer dynein arms have different functions in the generation of microtubule-based motility.	tmpzr1t_l9r_go_relaxed.owl	inner dynein arm complex							bf	2012-03-21T01:24:54Z					cellular_component											owl:Class	
GO:1900198	biolink:NamedThing	positive regulation of penicillin biosynthetic process	Any process that activates or increases the frequency, rate or extent of penicillin biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	upregulation of penicillin biosynthesis|positive regulation of penicillin formation|upregulation of penicillin biosynthetic process|up-regulation of penicillin anabolism|activation of penicillin anabolism|positive regulation of penicillin anabolism|positive regulation of penicillin biosynthesis|up-regulation of penicillin biosynthetic process|up regulation of penicillin anabolism|up regulation of penicillin formation|activation of penicillin biosynthesis|activation of penicillin biosynthetic process|activation of penicillin formation|up regulation of penicillin biosynthesis|upregulation of penicillin anabolism|positive regulation of penicillin synthesis|upregulation of penicillin formation|up-regulation of penicillin synthesis|up regulation of penicillin biosynthetic process|up-regulation of penicillin biosynthesis|up-regulation of penicillin formation|up regulation of penicillin synthesis|upregulation of penicillin synthesis|activation of penicillin synthesis							di	2012-03-20T03:56:52Z					biological_process											owl:Class	
GO:0075281	biolink:NamedThing	positive regulation of uredinium development	Any process that activates, maintains or increases the frequency, rate or extent of uredinium development, a process that leads to the formation of a reddish, pustule-like structure formed by a rust fungus and consisting of uredospores.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0075280	biolink:NamedThing	regulation of uredinium development	Any process that modulates the frequency, rate or extent of uredinium development, a process that leads to the formation of a reddish, pustule-like structure formed by a rust fungus and consisting of uredospores.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0018505	biolink:NamedThing	cis-1,2-dihydro-1,2-dihydroxynaphthalene dehydrogenase activity	Catalysis of the reaction: cis-1,2-dihydronaphthalene-1,2-diol + NAD+ = naphthalene-1,2-diol + NADH + H+.	tmpzr1t_l9r_go_relaxed.owl	1,2-dihydroxy-1,2-dihydroxynaphthalene dehydrogenase activity|(+)-cis-naphthalene dihydrodiol dehydrogenase activity|cis-naphthalene dihydrodiol dehydrogenase activity|naphthalene dihydrodiol dehydrogenase activity|cis-1,2-dihydronaphthalene-1,2-diol:NAD+ 1,2-oxidoreductase activity|cis-dihydrodiol naphthalene dehydrogenase activity				RHEA:11832|UM-BBD_enzymeID:e0122|EC:1.3.1.29|MetaCyc:1.3.1.29-RXN									molecular_function											owl:Class	
GO:0006627	biolink:NamedThing	protein processing involved in protein targeting to mitochondrion	The cleavage of peptide bonds in proteins, usually near the N terminus, contributing to the process of import into the mitochondrion. Several different peptidases mediate cleavage of proteins destined for different mitochondrial compartments.	tmpzr1t_l9r_go_relaxed.owl	mitochondrial protein processing during import|mitochondrial processing													biological_process											owl:Class	
GO:1901747	biolink:NamedThing	prephenate(2-) biosynthetic process	The chemical reactions and pathways resulting in the formation of prephenate(2-).	tmpzr1t_l9r_go_relaxed.owl	prephenate biosynthesis|prephenate(2-) formation|prephenate(2-) biosynthesis|prephenate formation|prephenate(2-) synthesis|prephenate anabolism|prephenate synthesis|prephenate(2-) anabolism							yaf	2013-01-14T10:13:57Z					biological_process											owl:Class	
GO:1901745	biolink:NamedThing	prephenate(2-) metabolic process	The chemical reactions and pathways involving prephenate(2-).	tmpzr1t_l9r_go_relaxed.owl	prephenate metabolism|prephenate(2-) metabolism							yaf	2013-01-14T10:13:49Z					biological_process											owl:Class	
GO:0047301	biolink:NamedThing	valine-3-methyl-2-oxovalerate transaminase activity	Catalysis of the reaction: (S)-3-methyl-2-oxopentanoate + L-valine = 3-methyl-2-oxobutanoate + L-isoleucine.	tmpzr1t_l9r_go_relaxed.owl	valine--3-methyl-2-oxovalerate aminotransferase activity|valine-2-keto-methylvalerate aminotransferase activity|valine--isoleucine aminotransferase activity|valine-3-methyl-2-oxovalerate aminotransferase activity|L-valine:(S)-3-methyl-2-oxopentanoate aminotransferase activity|valine--isoleucine transaminase activity				KEGG_REACTION:R02200|MetaCyc:2.6.1.32-RXN|EC:2.6.1.32|RHEA:11468									molecular_function											owl:Class	
GO:0032079	biolink:NamedThing	positive regulation of endodeoxyribonuclease activity	Any process that activates or increases the frequency, rate or extent of endodeoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid by creating internal breaks.	tmpzr1t_l9r_go_relaxed.owl	upregulation of endodeoxyribonuclease activity|endodeoxyribonuclease activator|up-regulation of endodeoxyribonuclease activity|up regulation of endodeoxyribonuclease activity|stimulation of endodeoxyribonuclease activity|activation of endodeoxyribonuclease activity													biological_process											owl:Class	
GO:0036292	biolink:NamedThing	DNA rewinding	The process in which interchain hydrogen bonds between two single-stranded DNA (ssDNA) are reformed to regenerate double-stranded DNA (dsDNA). ssDNA is often bound and stabilized by proteins such as replication protein A (RPA) to form ssDNA bubbles. The bubbles can be rewound by ATP-dependent motors to reform base pairs between strands and thus dsDNA.	tmpzr1t_l9r_go_relaxed.owl	single-stranded DNA bubble rewinding|DNA annealing|RPA-dependent DNA rewinding							bf	2012-07-18T10:43:41Z					biological_process											owl:Class	
GO:0044835	biolink:NamedThing	hydrogen generation via nitrogenase	The chemical reactions and pathways resulting in the formation of H2 (dihydrogen) which involve a nitrogenase activity as one of the steps. This process is observed in cyanobacteria.	tmpzr1t_l9r_go_relaxed.owl								jl	2014-02-19T14:59:15Z					biological_process											owl:Class	
GO:1902422	biolink:NamedThing	hydrogen biosynthetic process	The chemical reactions and pathways resulting in the formation of H2 (dihydrogen).	tmpzr1t_l9r_go_relaxed.owl	hydrogen formation|dihydrogen synthesis|hydrogen biosynthesis|molecular hydrogen biosynthesis|hydrogen production|H2 biosynthesis|hydrogen generation|hydrogen anabolism|hydrogen synthesis							jl	2013-09-18T14:34:32Z					biological_process											owl:Class	
GO:0045942	biolink:NamedThing	negative regulation of phosphorus utilization	Any process that stops, prevents, or reduces the frequency, rate or extent of phosphorus utilization.	tmpzr1t_l9r_go_relaxed.owl	down regulation of phosphorus utilization|inhibition of phosphorus utilization|downregulation of phosphorus utilization|down-regulation of phosphorus utilization													biological_process											owl:Class	
GO:1904141	biolink:NamedThing	positive regulation of microglial cell migration	Any process that activates or increases the frequency, rate or extent of microglial cell migration.	tmpzr1t_l9r_go_relaxed.owl	upregulation of microglial cell migration|up-regulation of microglial cell migration|activation of microglial cell migration|up regulation of microglial cell migration							nc	2015-04-13T09:07:11Z					biological_process											owl:Class	
GO:1903977	biolink:NamedThing	positive regulation of glial cell migration	Any process that activates or increases the frequency, rate or extent of glial cell migration.	tmpzr1t_l9r_go_relaxed.owl	activation of glia cell migration|up regulation of glial cell migration|upregulation of glial cell migration|upregulation of glia cell migration|positive regulation of glia cell migration|up regulation of glia cell migration|up-regulation of glial cell migration|up-regulation of glia cell migration|activation of glial cell migration							nc	2015-03-02T15:13:43Z					biological_process											owl:Class	
GO:1900700	biolink:NamedThing	positive regulation of o-orsellinic acid biosynthetic process	Any process that activates or increases the frequency, rate or extent of o-orsellinic acid biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	upregulation of o-orsellinic acid synthesis|up regulation of o-orsellinic acid formation|activation of o-orsellinic acid biosynthetic process|up-regulation of o-orsellinic acid anabolism|positive regulation of o-orsellinic acid formation|positive regulation of o-orsellinic acid anabolism|upregulation of o-orsellinic acid biosynthesis|up regulation of o-orsellinic acid synthesis|up-regulation of o-orsellinic acid biosynthetic process|up-regulation of o-orsellinic acid biosynthesis|up-regulation of o-orsellinic acid formation|positive regulation of o-orsellinic acid biosynthesis|activation of o-orsellinic acid biosynthesis|positive regulation of o-orsellinic acid synthesis|activation of o-orsellinic acid synthesis|up regulation of o-orsellinic acid biosynthesis|activation of o-orsellinic acid formation|up regulation of o-orsellinic acid biosynthetic process|up-regulation of o-orsellinic acid synthesis|upregulation of o-orsellinic acid biosynthetic process|up regulation of o-orsellinic acid anabolism|upregulation of o-orsellinic acid formation|activation of o-orsellinic acid anabolism|upregulation of o-orsellinic acid anabolism							di	2012-05-22T04:57:16Z					biological_process											owl:Class	
GO:1901847	biolink:NamedThing	nicotinate metabolic process	The chemical reactions and pathways involving nicotinate.	tmpzr1t_l9r_go_relaxed.owl	nicotinate metabolism							yaf	2013-01-28T11:23:48Z					biological_process											owl:Class	
GO:0072524	biolink:NamedThing	pyridine-containing compound metabolic process	The chemical reactions and pathways involving a pyridine-containing compound, i.e. any compound that contains pyridine or a formal derivative thereof.	tmpzr1t_l9r_go_relaxed.owl	pyridine and derivative metabolic process|pyridine-containing compound metabolism							mah	2011-01-04T03:21:47Z					biological_process											owl:Class	
GO:0036034	biolink:NamedThing	mediator complex assembly	The aggregation, arrangement and bonding together of a set of components to form a mediator complex. The mediator complex is a protein complex that interacts with the carboxy-terminal domain of the largest subunit of RNA polymerase II and plays an active role in transducing the signal from a transcription factor to the transcriptional machinery. The Saccharomyces complex contains several identifiable subcomplexes: a head domain comprising Srb2, -4, and -5, Med6, -8, and -11, and Rox3 proteins; a middle domain comprising Med1, -4, and -7, Nut1 and -2, Cse2, Rgr1, Soh1, and Srb7 proteins; a tail consisting of Gal11p, Med2p, Pgd1p, and Sin4p; and a regulatory subcomplex comprising Ssn2, -3, and -8, and Srb8 proteins. Metazoan mediator complexes have similar modular structures and include homologs of yeast Srb and Med proteins.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-10-31T05:18:11Z					biological_process											owl:Class	
GO:0044572	biolink:NamedThing	[4Fe-4S] cluster assembly	The incorporation of four iron atoms and four sulfur atoms into an iron-sulfur cluster.	tmpzr1t_l9r_go_relaxed.owl	[4Fe-4S] cluster biosynthetic process|4Fe-4S cluster assembly							jl	2012-04-18T03:19:23Z					biological_process											owl:Class	
GO:0097257	biolink:NamedThing	leukotriene B4 12-hydroxy dehydrogenase activity	Catalysis of the reaction: leukotriene B4 + NADP(+) = 12-oxo-leukotriene B4 + NADPH + H(+).	tmpzr1t_l9r_go_relaxed.owl	leukotriene B4 12-hydroxydehydrogenase activity				RHEA:50608|Reactome:R-HSA-2161567			pr	2012-03-07T02:07:41Z					molecular_function											owl:Class	
GO:0034968	biolink:NamedThing	histone lysine methylation	The modification of a histone by addition of one or more methyl groups to a lysine residue.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0016100	biolink:NamedThing	monoterpenoid catabolic process	The chemical reactions and pathways resulting in the breakdown of monoterpenoid compounds, terpenoids having a C10 skeleton.	tmpzr1t_l9r_go_relaxed.owl	monoterpenoid breakdown|monoterpenoid catabolism|monoterpenoid degradation													biological_process											owl:Class	
GO:0016098	biolink:NamedThing	monoterpenoid metabolic process	The chemical reactions and pathways involving monoterpenoid compounds, terpenoids having a C10 skeleton.	tmpzr1t_l9r_go_relaxed.owl	monoterpenoid metabolism													biological_process											owl:Class	
GO:0005875	biolink:NamedThing	microtubule associated complex	Any multimeric complex connected to a microtubule.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0045634	biolink:NamedThing	regulation of melanocyte differentiation	Any process that modulates the frequency, rate or extent of melanocyte differentiation.	tmpzr1t_l9r_go_relaxed.owl	regulation of melanophore differentiation													biological_process											owl:Class	
GO:0050932	biolink:NamedThing	regulation of pigment cell differentiation	Any process that modulates the frequency, rate or extent of pigmented cell differentiation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0071110	biolink:NamedThing	histone biotinylation	The modification of a histone by the addition of a biotinyl group.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-11-13T01:22:59Z					biological_process											owl:Class	
GO:0016570	biolink:NamedThing	histone modification	The covalent alteration of one or more amino acid residues within a histone protein.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Histone#Histone_modifications_in_chromatin_regulation									biological_process											owl:Class	
GO:1905901	biolink:NamedThing	positive regulation of smooth muscle tissue development	Any process that activates or increases the frequency, rate or extent of smooth muscle tissue development.	tmpzr1t_l9r_go_relaxed.owl	up regulation of smooth muscle tissue development|activation of smooth muscle tissue development|upregulation of smooth muscle tissue development|up-regulation of smooth muscle tissue development							bhm	2017-02-01T14:31:33Z					biological_process											owl:Class	
GO:0052933	biolink:NamedThing	alcohol dehydrogenase (cytochrome c(L)) activity	Catalysis of the reaction: 2 [Fe(III)cytochrome cL] + a primary alcohol = 2 [Fe(II)cytochrome cL] + an aldehyde + 2 H+.	tmpzr1t_l9r_go_relaxed.owl	2-chloroethanol cytochrome-c oxidoreductase activity|alcohol:cytochrome c(L) oxidoreductase activity|methanol dehydrogenase activity|ethanol cytochrome-c oxidoreductase activity|methanol ferricytochrome-c oxidoreductase activity	https://github.com/geneontology/go-ontology/issues/21412			KEGG_REACTION:R09128|KEGG_REACTION:R01146|MetaCyc:RXN-2861|MetaCyc:RXN-11332|KEGG_REACTION:R09127|RHEA:51004|EC:1.1.2.7							GO:0052931|GO:0052930|GO:0052932		molecular_function											owl:Class	
GO:0016898	biolink:NamedThing	oxidoreductase activity, acting on the CH-OH group of donors, cytochrome as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces a cytochrome molecule.	tmpzr1t_l9r_go_relaxed.owl					EC:1.1.2.-									molecular_function											owl:Class	
GO:0033895	biolink:NamedThing	ribonuclease [poly-(U)-specific] activity	Catalysis of the endonucleolytic cleavage of poly(U) to fragments terminated by 3'-hydroxy and 5'-phosphate groups.	tmpzr1t_l9r_go_relaxed.owl	ribonuclease (uracil-specific) activity|uracil-specific RNase activity|uracil-specific endoribonuclease activity				EC:3.1.26.9									molecular_function											owl:Class	
GO:0043977	biolink:NamedThing	histone H2A-K5 acetylation	The modification of histone H2A by the addition of an acetyl group to a lysine residue at position 5 of the histone.	tmpzr1t_l9r_go_relaxed.owl	histone H2A acetylation at K5													biological_process											owl:Class	
GO:0043968	biolink:NamedThing	histone H2A acetylation	The modification of histone H2A by the addition of an acetyl group.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0099629	biolink:NamedThing	postsynaptic specialization of symmetric synapse	A network of proteins within and adjacent to the postsynaptic membrane of a symmetric synapse, consisting of anchoring and scaffolding molecules, signaling enzymes and cytoskeletal components that spatially and functionally organize the neurotransmitter receptors at the synapse. This structure is not as thick or electron dense as the postsynaptic densities found in asymmetric synapses.	tmpzr1t_l9r_go_relaxed.owl	postsynaptic density of inhibitory synapse													cellular_component											owl:Class	
GO:0099572	biolink:NamedThing	postsynaptic specialization	A network of proteins within and adjacent to the postsynaptic membrane. Its major components include neurotransmitter receptors and the proteins that spatially and functionally organize them such as anchoring and scaffolding molecules, signaling enzymes and cytoskeletal components.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0050970	biolink:NamedThing	detection of electrical stimulus involved in magnetoreception	The series of events that contribute to magnetoception in which an electrical stimulus is received and converted into a molecular signal. The stimulus is in the form of an induced electric field resulting from movement in a magnetic field.	tmpzr1t_l9r_go_relaxed.owl	magnetoception, sensory transduction of electrical stimulus|magnetoreception, sensory detection of electrical stimulus|sensory transduction of electrical stimulus during magnetoreception|sensory detection of electrical stimulus during magnetoreception|magnetoreception, sensory transduction of electrical stimulus|detection of electrical stimulus during magnetoreception|magnetoreception, detection of electrical stimulus													biological_process											owl:Class	
GO:1905155	biolink:NamedThing	positive regulation of membrane invagination	Any process that activates or increases the frequency, rate or extent of membrane invagination.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of membrane invagination|up regulation of membrane invagination|upregulation of membrane invagination|activation of membrane invagination							bf	2016-04-18T15:44:12Z					biological_process											owl:Class	
GO:0071592	biolink:NamedThing	nicotinic acid riboside biosynthetic process	The chemical reactions and pathways resulting in the formation of nicotinic acid riboside, the product of the formation of a glycosidic bond between ribose and nicotinic acid.	tmpzr1t_l9r_go_relaxed.owl	nicotinic acid riboside formation|D-ribosylnicotinic acid biosynthetic process|nicotinic acid riboside biosynthesis|nicotinic acid riboside anabolism|nicotinic acid riboside synthesis							mah	2010-01-29T12:01:25Z					biological_process											owl:Class	
GO:0071591	biolink:NamedThing	nicotinic acid riboside metabolic process	The chemical reactions and pathways involving nicotinic acid riboside, the product of the formation of a glycosidic bond between ribose and nicotinic acid.	tmpzr1t_l9r_go_relaxed.owl	nicotinic acid riboside metabolism|D-ribosylnicotinic acid metabolic process							mah	2010-01-29T11:50:42Z					biological_process											owl:Class	
GO:0021535	biolink:NamedThing	cell migration in hindbrain	The orderly movement of a cell that will reside in the hindbrain.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0097737	biolink:NamedThing	acquisition of mycelium reproductive competence	A maturation process by which an organism acquires the ability to reproduce. In fungi, reproductive competence only occurs in a population of filamentous cells that form a mycelium.	tmpzr1t_l9r_go_relaxed.owl	mycelium developmental competence							pr	2016-10-14T16:36:09Z					biological_process											owl:Class	
GO:0003401	biolink:NamedThing	axis elongation	The developmental growth that results in the elongation of a line that defines polarity or symmetry in an anatomical structure.	tmpzr1t_l9r_go_relaxed.owl	elongation of an axis							dph	2009-12-21T01:12:15Z					biological_process											owl:Class	
GO:0051793	biolink:NamedThing	medium-chain fatty acid catabolic process	The chemical reactions and pathways resulting in the breakdown of any fatty acid with a chain length of between C6 and C12.	tmpzr1t_l9r_go_relaxed.owl	medium chain fatty acid catabolism|medium-chain fatty acid catabolism|medium-chain fatty acid degradation|medium-chain fatty acid breakdown|medium chain fatty acid catabolic process													biological_process											owl:Class	
GO:0051791	biolink:NamedThing	medium-chain fatty acid metabolic process	The chemical reactions and pathways involving medium-chain fatty acids, any fatty acid with a chain length of between C6 and C12.	tmpzr1t_l9r_go_relaxed.owl	medium-chain fatty acid metabolism|medium chain fatty acid metabolic process|medium chain fatty acid metabolism													biological_process											owl:Class	
GO:0120118	biolink:NamedThing	flagella connector	A mobile transmembrane junction at the tip of the flagellum of some kinetoplastid species linking the tip of a new growing flagellum to an older flagellum.	tmpzr1t_l9r_go_relaxed.owl						Note that we deem cilium and microtubule-based flagellum to be equivalent; the primary term name reflects frequency of use.		krc	2017-12-11T22:24:17Z					cellular_component											owl:Class	
GO:0030054	biolink:NamedThing	cell junction	A cellular component that forms a specialized region of connection between two or more cells, or between a cell and the extracellular matrix, or between two membrane-bound components of a cell, such as flagella.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Cell_junction									cellular_component											owl:Class	
GO:0036431	biolink:NamedThing	dCMP kinase activity	Catalysis of the reaction: ATP + dCMP = ADP + dCDP.	tmpzr1t_l9r_go_relaxed.owl	ATP:dCMP phosphotransferase activity				MetaCyc:RXN-7913|RHEA:25094|MetaCyc:RXN-11831|KEGG_REACTION:R01665			bf	2013-09-16T14:11:56Z					molecular_function											owl:Class	
GO:2001205	biolink:NamedThing	negative regulation of osteoclast development	Any process that stops, prevents or reduces the frequency, rate or extent of osteoclast development.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of osteoclast cell development							yaf	2011-11-10T10:59:06Z					biological_process											owl:Class	
GO:0102232	biolink:NamedThing	acrolein reductase activity	Catalysis of the reaction: acrolein + NADPH + H+ <=> propanal + NADP.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-12281									molecular_function											owl:Class	
GO:0070571	biolink:NamedThing	negative regulation of neuron projection regeneration	Any process that stops, prevents, or reduces the frequency, rate or extent of neuron projection regeneration, the regrowth of neuronal processes such as axons or dendrites following their loss or damage.	tmpzr1t_l9r_go_relaxed.owl	growth cone collapse							mah	2009-04-15T01:43:19Z					biological_process											owl:Class	
GO:0036219	biolink:NamedThing	GTP diphosphatase activity	Catalysis of the reaction: GTP + H2O = GMP + diphosphate.	tmpzr1t_l9r_go_relaxed.owl	GTP diphosphohydrolase activity|GTP diphosphohydrolase (diphosphate-forming); guanosine 5'-triphosphate pyrophosphohydrolase				RHEA:29391|KEGG_REACTION:R00426			bf	2012-05-08T01:47:59Z					molecular_function											owl:Class	
GO:0097019	biolink:NamedThing	neurotransmitter receptor catabolic process	The chemical reactions and pathways resulting in the breakdown of neurotransmitter receptors.	tmpzr1t_l9r_go_relaxed.owl	neurotransmitter receptor degradation|neurotransmitter receptor catabolism|neurotransmitter receptor breakdown							pr	2011-03-23T04:16:11Z					biological_process											owl:Class	
GO:0045213	biolink:NamedThing	neurotransmitter receptor metabolic process	The chemical reactions and pathways involving neurotransmitter receptors.	tmpzr1t_l9r_go_relaxed.owl	neurotransmitter receptor metabolism													biological_process											owl:Class	
GO:0009124	biolink:NamedThing	nucleoside monophosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of a nucleoside monophosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with phosphate on the sugar.	tmpzr1t_l9r_go_relaxed.owl	nucleoside monophosphate anabolism|nucleoside monophosphate formation|nucleoside monophosphate synthesis|nucleoside monophosphate biosynthesis													biological_process											owl:Class	
GO:0015410	biolink:NamedThing	ABC-type manganese transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Mn2+(out) = ADP + phosphate + Mn2+(in).	tmpzr1t_l9r_go_relaxed.owl	ABC-type Mn(2+) transporter|manganese-transporting ATPase activity|manganese ABC transporter|ATPase-coupled manganese transmembrane transporter activity|manganese transmembrane transporter activity, phosphorylative mechanism|ATP-dependent manganese transmembrane transporter activity				MetaCyc:3.6.3.35-RXN|EC:7.2.2.5|RHEA:17365|Reactome:R-HSA-5692462									molecular_function											owl:Class	
GO:0005452	biolink:NamedThing	inorganic anion exchanger activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: inorganic anion A(out) + inorganic anion B(in) = inorganic anion A(in) + inorganic anion B(out).	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-425577|Reactome:R-HSA-425482|Reactome:R-HSA-5656248|Reactome:R-HSA-1237038|Reactome:R-HSA-5627737|Reactome:R-HSA-427666|Reactome:R-HSA-1247665									molecular_function											owl:Class	
GO:0050638	biolink:NamedThing	taxadien-5-alpha-ol O-acetyltransferase activity	Catalysis of the reaction: acetyl-CoA + taxa-4(20),11-dien-5alpha-ol = CoA + taxa-4(20),11-dien-5alpha-yl acetate.	tmpzr1t_l9r_go_relaxed.owl	acetyl-CoA:taxa-4(20),11-dien-5alpha-ol O-acetyltransferase activity|taxa-4(20),11(12)-dien-5alpha-ol-O-acetyltransferase activity|taxadien-5alpha-ol O-acetyltransferase activity|taxadien-5a-ol O-acetyltransferase activity|acetyl coenzyme A: taxa-4(20),11(12)-dien-5alpha-ol O-acetyl transferase activity|acetyl coenzyme A:taxa-4(20),11(12)-dien-5-alpha-ol O-acetyl transferase activity|taxadienol acetyltransferase activity				MetaCyc:2.3.1.162-RXN|RHEA:22028|KEGG_REACTION:R06307|EC:2.3.1.162									molecular_function											owl:Class	
GO:0016413	biolink:NamedThing	O-acetyltransferase activity	Catalysis of the transfer of an acetyl group to an oxygen atom on the acceptor molecule.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0046004	biolink:NamedThing	positive regulation of syncytial blastoderm mitotic cell cycle	Any process that activates or increases the rate or extent of progression through the syncytial blastoderm mitotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl	stimulation of progression through syncytial blastoderm mitotic cell cycle|up-regulation of progression through syncytial blastoderm mitotic cell cycle|up regulation of progression through syncytial blastoderm mitotic cell cycle|positive regulation of syncytial blastoderm cell cycle progression|positive regulation of progression through syncytial blastoderm mitotic cell cycle|activation of progression through syncytial blastoderm mitotic cell cycle|upregulation of progression through syncytial blastoderm mitotic cell cycle													biological_process											owl:Class	
GO:0045977	biolink:NamedThing	positive regulation of mitotic cell cycle, embryonic	Any process that activates or increases the frequency, rate or extent of progression through the embryonic mitotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of embryonic mitotic cell cycle|activation of mitotic cell cycle, embryonic|positive regulation of progression through embryonic mitotic cell cycle|up-regulation of mitotic cell cycle, embryonic|stimulation of mitotic cell cycle, embryonic|upregulation of mitotic cell cycle, embryonic|positive regulation of embryonic mitotic cell cycle progression|up regulation of mitotic cell cycle, embryonic													biological_process											owl:Class	
GO:1903085	biolink:NamedThing	regulation of sinapate ester biosynthetic process	Any process that modulates the frequency, rate or extent of sinapate ester biosynthesis.	tmpzr1t_l9r_go_relaxed.owl	regulation of sinapate ester synthesis|regulation of sinapate ester biosynthesis|regulation of sinapate ester anabolism|regulation of sinapate ester formation							tb	2014-05-30T22:00:12Z					biological_process											owl:Class	
GO:1905818	biolink:NamedThing	regulation of chromosome separation	Any process that modulates the frequency, rate or extent of chromosome separation.	tmpzr1t_l9r_go_relaxed.owl	regulation of rDNA separation|regulation of chromatid release							bhm	2017-01-13T13:55:18Z					biological_process											owl:Class	
GO:0060046	biolink:NamedThing	regulation of acrosome reaction	Any process that modulates the frequency, rate or extent of the acrosome reaction.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0072055	biolink:NamedThing	renal cortex development	The process whose specific outcome is the progression of the renal cortex over time, from its formation to the mature structure. The renal cortex is the outer region of the kidney.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-01-25T04:01:12Z					biological_process											owl:Class	
GO:0008121	biolink:NamedThing	ubiquinol-cytochrome-c reductase activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: CoQH2 + 2 ferricytochrome c = CoQ + 2 ferrocytochrome c + 2 H+.	tmpzr1t_l9r_go_relaxed.owl	ubiquinone-cytochrome c reductase activity|electron transporter, transferring electrons within CoQH2-cytochrome c reductase complex activity|ubiquinol-cytochrome c1 oxidoreductase activity|mitochondrial electron transport complex III|cytochrome a3/copper complex|complex III (mitochondrial electron transport) activity|soluble cytochrome b562|ubiquinone-cytochrome c oxidoreductase activity|ubiquinol:ferricytochrome-c oxidoreductase activity|ubiquinone--cytochrome-c oxidoreductase activity|electron transporter, transferring electrons within cytochrome c oxidase complex activity|cytochrome a|ubiquinol-cytochrome c oxidoreductase activity|ubiquinol-cytochrome c2 reductase activity|cytochrome c1|ubiquinol-cytochrome c-2 oxidoreductase activity|cytochrome b562|cytochrome b566|cytochrome	https://github.com/geneontology/go-ontology/issues/20616|https://github.com/geneontology/go-ontology/issues/21275			RHEA:11484|EC:7.1.1.8|Reactome:R-HSA-164651|MetaCyc:1.10.2.2-RXN							GO:0045153|GO:0045154		molecular_function											owl:Class	
GO:0044752	biolink:NamedThing	response to human chorionic gonadotropin	Any process that results in a change in state or activity of a cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a human chorionic gonadotropin stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to human chorionic gonadotropin stimulus							jl	2012-11-20T16:21:08Z					biological_process											owl:Class	
GO:0034698	biolink:NamedThing	response to gonadotropin	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gonadotropin stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to gonadotropin stimulus													biological_process											owl:Class	
GO:0048083	biolink:NamedThing	negative regulation of adult chitin-containing cuticle pigmentation	Any process that stops, prevents, or reduces the frequency, rate or extent of establishment of the adult pattern of pigmentation in the cuticle of an organism.	tmpzr1t_l9r_go_relaxed.owl	down regulation of adult chitin-containing cuticle pigmentation|downregulation of adult chitin-containing cuticle pigmentation|down-regulation of adult chitin-containing cuticle pigmentation|inhibition of adult chitin-containing cuticle pigmentation													biological_process											owl:Class	
GO:0045800	biolink:NamedThing	negative regulation of chitin-based cuticle tanning	Any process that stops, prevents, or reduces the frequency, rate or extent of chitin-based cuticular tanning.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of cuticle tanning|negative regulation of cuticle tanning|inhibition of cuticle tanning|down regulation of cuticle tanning|negative regulation of cuticle hardening|downregulation of cuticle tanning													biological_process											owl:Class	
GO:0030311	biolink:NamedThing	poly-N-acetyllactosamine biosynthetic process	The chemical reactions and pathways resulting in the formation of poly-N-acetyllactosamine, a carbohydrate composed of N-acetyllactosamine repeats (Gal-beta-1,4-GlcNAc-beta-1,3)n.	tmpzr1t_l9r_go_relaxed.owl	poly-N-acetyllactosamine biosynthesis|poly-N-acetyllactosamine synthesis|poly-N-acetyllactosamine formation|poly-N-acetyllactosamine anabolism													biological_process											owl:Class	
GO:0003012	biolink:NamedThing	muscle system process	A organ system process carried out at the level of a muscle. Muscle tissue is composed of contractile cells or fibers.	tmpzr1t_l9r_go_relaxed.owl	muscle physiological process													biological_process											owl:Class	
GO:0035998	biolink:NamedThing	7,8-dihydroneopterin 3'-triphosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of 7,8-dihydroneopterin 3'-triphosphate.	tmpzr1t_l9r_go_relaxed.owl	7,8-dihydroneopterin 3'-triphosphate synthesis|7,8-dihydroneopterin 3'-triphosphate formation|7,8-dihydroneopterin 3'-triphosphate anabolism|7,8-dihydroneopterin 3'-triphosphate biosynthesis				UniPathway:UPA00848			bf	2011-09-02T01:15:35Z					biological_process											owl:Class	
GO:0060625	biolink:NamedThing	regulation of protein deneddylation	Any process that modulates the rate, frequency, or extent of protein deneddylation, the removal of a ubiquitin-like protein of the NEDD8 type from a protein.	tmpzr1t_l9r_go_relaxed.owl	regulation of cullin deneddylation							dph	2009-05-18T02:22:07Z			GO:0060626		biological_process											owl:Class	
GO:0075287	biolink:NamedThing	positive regulation of sporangiospore formation	Any process that activates, maintains or increases the frequency, rate or extent of sporangiospore formation, a process in which sporangiospores, a type of asexual spore found in fungi, are formed. Sporangiospores are formed within sac-like structure, the sporangium, following the division of the cytoplasm.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1905033	biolink:NamedThing	positive regulation of membrane repolarization during cardiac muscle cell action potential	Any process that activates or increases the frequency, rate or extent of membrane repolarization during cardiac muscle cell action potential.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of membrane repolarization during cardiac muscle cell action potential|upregulation of membrane repolarization during cardiac muscle cell action potential|up regulation of membrane repolarization during cardiac muscle cell action potential|activation of membrane repolarization during cardiac muscle cell action potential							rph	2016-03-07T10:24:53Z					biological_process											owl:Class	
GO:0033689	biolink:NamedThing	negative regulation of osteoblast proliferation	Any process that stops, prevents or reduces the rate or extent of osteoblast proliferation.	tmpzr1t_l9r_go_relaxed.owl	down regulation of osteoblast proliferation|inhibition of osteoblast proliferation|down-regulation of osteoblast proliferation|downregulation of osteoblast proliferation													biological_process											owl:Class	
GO:0018772	biolink:NamedThing	trioxoheptanoate hydrolase activity	Catalysis of the reaction: 2,4,6-trioxoheptanoate + H2O = acetylpyruvate + acetate.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:R306-RXN|UM-BBD_reactionID:r0094									molecular_function											owl:Class	
GO:0036178	biolink:NamedThing	filamentous growth of a population of unicellular organisms in response to neutral pH	The process in which a group of unicellular organisms grow in a threadlike, filamentous shape in response to a neutral pH (pH close to 7) stimulus.	tmpzr1t_l9r_go_relaxed.owl								bf	2012-03-29T01:43:47Z					biological_process											owl:Class	
GO:1905667	biolink:NamedThing	negative regulation of protein localization to endosome	Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to endosome.	tmpzr1t_l9r_go_relaxed.owl	downregulation of protein localization to endosome|down-regulation of protein localization in endosome|down regulation of protein localisation in endosome|down regulation of protein localization in endosome|downregulation of protein localization in endosome|down regulation of protein localization to endosome|inhibition of protein localisation in endosome|inhibition of protein localization to endosome|inhibition of protein localization in endosome|downregulation of protein localisation in endosome|down-regulation of protein localisation in endosome|negative regulation of protein localisation in endosome|negative regulation of protein localization in endosome|down-regulation of protein localization to endosome							bc	2016-11-11T11:19:09Z					biological_process											owl:Class	
GO:0089719	biolink:NamedThing	RHG protein domain binding	Binding to an RHG (reaper/hid/grimm) domain/motif (AKA iap binding motif).	tmpzr1t_l9r_go_relaxed.owl	RHG domain binding|iap binding domain binding|inhibitor of apoptosis binding domain binding|reaper hid grim domain binding													molecular_function											owl:Class	
GO:1905024	biolink:NamedThing	regulation of membrane repolarization during ventricular cardiac muscle cell action potential	Any process that modulates the frequency, rate or extent of membrane repolarization during ventricular cardiac muscle cell action potential.	tmpzr1t_l9r_go_relaxed.owl	regulation of ventricular repolarization|regulation of electrocardiogram T wave|regulation of regulation of ventricular cardiac muscle repolarization							rph	2016-03-04T11:19:02Z					biological_process											owl:Class	
GO:0005996	biolink:NamedThing	monosaccharide metabolic process	The chemical reactions and pathways involving monosaccharides, the simplest carbohydrates. They are polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms. They form the constitutional repeating units of oligo- and polysaccharides.	tmpzr1t_l9r_go_relaxed.owl	monosaccharide metabolism													biological_process											owl:Class	
GO:0032340	biolink:NamedThing	positive regulation of inhibin secretion	Any process that activates or increases the frequency, rate or extent of the regulated release of inhibin from a cell.	tmpzr1t_l9r_go_relaxed.owl	upregulation of inhibin secretion|up-regulation of inhibin secretion|activation of inhibin secretion|up regulation of inhibin secretion|stimulation of inhibin secretion													biological_process											owl:Class	
GO:0051108	biolink:NamedThing	carnitine-CoA ligase activity	Catalysis of the reaction: D-carnitine + CoA + ATP = AMP + diphosphate + D-carnitinyl-CoA.	tmpzr1t_l9r_go_relaxed.owl	carnitine synthetase activity|crotonobetaine/carnitine-CoA ligase activity				RHEA:30543|MetaCyc:DCARNCOALIG-RXN									molecular_function											owl:Class	
GO:0034266	biolink:NamedThing	isopentenyl adenine catabolic process	The chemical reactions and pathways resulting in the breakdown of the cytokinin 6-isopentenyladenine.	tmpzr1t_l9r_go_relaxed.owl	isopentenyl adenine degradation|isopentenyl adenine breakdown|isopentenyl adenine catabolism|isopentenyladenine catabolic process													biological_process											owl:Class	
GO:0009823	biolink:NamedThing	cytokinin catabolic process	The chemical reactions and pathways resulting in the breakdown of cytokinins, a class of adenine-derived compounds that can function in plants as plant growth regulators.	tmpzr1t_l9r_go_relaxed.owl	cytokinin catabolism|cytokinin degradation|cytokinin breakdown													biological_process											owl:Class	
GO:0097011	biolink:NamedThing	cellular response to granulocyte macrophage colony-stimulating factor stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a granulocyte macrophage colony-stimulating factor stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to GM-CSF stimulus							pr	2011-03-21T05:25:06Z					biological_process											owl:Class	
GO:0097012	biolink:NamedThing	response to granulocyte macrophage colony-stimulating factor	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a granulocyte macrophage colony-stimulating factor stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to granulocyte macrophage colony-stimulating factor stimulus|response to GM-CSF							pr	2011-03-22T01:12:15Z					biological_process											owl:Class	
GO:0098730	biolink:NamedThing	male germline stem cell symmetric division	The symmetric division of a male germline stem cell to produce two male germline stem cells.  An example of this is found in mammalian spermatogonial stem cells, some proportion of which divide symmetrically, so amplifying the population. The choice between asymmetric and symmetric division in this case appears to be internal and stochastic.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0098729	biolink:NamedThing	germline stem cell symmetric division	Division of a germline stem cell to produce two germline stem cells of the same type as the parent.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0045682	biolink:NamedThing	regulation of epidermis development	Any process that modulates the frequency, rate or extent of epidermis development.	tmpzr1t_l9r_go_relaxed.owl	regulation of epidermal development|regulation of hypodermis development													biological_process											owl:Class	
GO:0048663	biolink:NamedThing	neuron fate commitment	The process in which the developmental fate of a cell becomes restricted such that it will develop into a neuron.	tmpzr1t_l9r_go_relaxed.owl	neuron lineage restriction|neuronal lineage restriction											GO:0042055		biological_process											owl:Class	
GO:0034296	biolink:NamedThing	zygospore formation	The process in which zygospores are formed. Zygospores are characteristic of the zygomycete fungi (phylum Zygomycota) thick-walled and darkly colored, and usually heavily ornamented as well, with many spines or ridges. It is formed between two specialized organs called suspensors, which are themselves usually heavily ornamented, one from each mating partner. The zygospore forms between them and then breaks away.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0043935	biolink:NamedThing	sexual sporulation resulting in formation of a cellular spore	The formation of spores derived from the products of meiosis. A cellular spore is a cell form that can be used for dissemination, for survival of adverse conditions because of its heat and dessication resistance, and/or for reproduction.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1901491	biolink:NamedThing	negative regulation of lymphangiogenesis	Any process that stops, prevents or reduces the frequency, rate or extent of lymphangiogenesis.	tmpzr1t_l9r_go_relaxed.owl	downregulation of lymphangiogenesis|downregulation of lymph vessel formation|inhibition of lymphangiogenesis|down-regulation of lymph vessel formation|down regulation of lymphangiogenesis|down regulation of lymph vessel formation|inhibition of lymph vessel formation|down-regulation of lymphangiogenesis|negative regulation of lymph vessel formation							dph	2012-10-15T13:08:21Z					biological_process											owl:Class	
GO:0007318	biolink:NamedThing	pole plasm protein localization	Any process in which a protein is transported to, or maintained in, the oocyte pole plasm. An example of this is found in Drosophila melanogaster.	tmpzr1t_l9r_go_relaxed.owl	pole plasm protein localisation|oocyte pole plasm protein localization|establishment and maintenance of pole plasm protein localization											GO:0048115		biological_process											owl:Class	
GO:0017182	biolink:NamedThing	peptidyl-diphthamide metabolic process	The chemical reactions and pathways involving peptidyl-diphthamide, a modified histidine residue.	tmpzr1t_l9r_go_relaxed.owl	peptidyl-diphthamide metabolism													biological_process											owl:Class	
GO:0046091	biolink:NamedThing	deoxyadenosine biosynthetic process	The chemical reactions and pathways resulting in the formation of deoxyadenosine, 2-deoxyribosyladenine, one of the four major nucleosides of DNA.	tmpzr1t_l9r_go_relaxed.owl	deoxyadenosine biosynthesis|deoxyadenosine anabolism|deoxyadenosine formation|deoxyadenosine synthesis													biological_process											owl:Class	
GO:0046090	biolink:NamedThing	deoxyadenosine metabolic process	The chemical reactions and pathways involving deoxyadenosine, 2-deoxyribosyladenine, one of the four major nucleosides of DNA.	tmpzr1t_l9r_go_relaxed.owl	deoxyadenosine metabolism													biological_process											owl:Class	
GO:0019624	biolink:NamedThing	atrazine catabolic process to isopropylamine	The chemical reactions and pathways resulting in the breakdown of atrazine, a triazine ring-containing herbicide, into isopropylamine.	tmpzr1t_l9r_go_relaxed.owl	atrazine degradation to isopropylamine|atrazine breakdown to isopropylamine													biological_process											owl:Class	
GO:0046187	biolink:NamedThing	acetaldehyde catabolic process	The chemical reactions and pathways resulting in the breakdown of acetaldehyde, a colorless, flammable liquid intermediate in the metabolism of alcohol.	tmpzr1t_l9r_go_relaxed.owl	acetaldehyde catabolism|acetaldehyde degradation|acetaldehyde breakdown													biological_process											owl:Class	
GO:0100002	biolink:NamedThing	negative regulation of protein kinase activity by protein phosphorylation	Any protein phosphorylation process that negatively regulates protein kinase activity.	tmpzr1t_l9r_go_relaxed.owl								cjm	2015-04-02T04:13:19Z					biological_process											owl:Class	
GO:0006468	biolink:NamedThing	protein phosphorylation	The process of introducing a phosphate group on to a protein.	tmpzr1t_l9r_go_relaxed.owl	protein amino acid phosphorylation													biological_process											owl:Class	
GO:0030350	biolink:NamedThing	iron-responsive element binding	Binding to an iron-responsive element, a regulatory sequence found in the 5'- and 3'-untranslated regions of mRNAs encoding many iron-binding proteins.	tmpzr1t_l9r_go_relaxed.owl	IRE binding													molecular_function											owl:Class	
GO:1905211	biolink:NamedThing	negative regulation of fibroblast chemotaxis	Any process that stops, prevents or reduces the frequency, rate or extent of fibroblast chemotaxis.	tmpzr1t_l9r_go_relaxed.owl	inhibition of fibroblast chemotaxis|downregulation of fibroblast chemotaxis|down regulation of fibroblast chemotaxis|down-regulation of fibroblast chemotaxis							sl	2016-06-02T20:08:51Z					biological_process											owl:Class	
GO:0009180	biolink:NamedThing	purine ribonucleoside diphosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of purine ribonucleoside diphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with diphosphate on the sugar.	tmpzr1t_l9r_go_relaxed.owl	purine ribonucleoside diphosphate formation|purine ribonucleoside diphosphate biosynthesis|purine ribonucleoside diphosphate anabolism|purine ribonucleoside diphosphate synthesis													biological_process											owl:Class	
GO:0044523	biolink:NamedThing	envenomation resulting in damage of muscle extracellular matrix in other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, damaging the extracellular matrix of muscle cells and ultimately resulting in muscle necrosis in the bitten organism.	tmpzr1t_l9r_go_relaxed.owl	envenomation resulting in damage of muscle extracellular matrix causing muscle necrosis in other organism							jl	2012-02-27T12:40:32Z					biological_process											owl:Class	
GO:1905396	biolink:NamedThing	cellular response to flavonoid	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a flavonoid stimulus.	tmpzr1t_l9r_go_relaxed.owl								sl	2016-08-24T15:01:02Z					biological_process											owl:Class	
GO:1900769	biolink:NamedThing	fonsecin biosynthetic process	The chemical reactions and pathways resulting in the formation of fonsecin.	tmpzr1t_l9r_go_relaxed.owl	fonsecin synthesis|fonsecin formation|fonsecin anabolism|fonsecin biosynthesis							di	2012-06-04T09:21:49Z					biological_process											owl:Class	
GO:0042671	biolink:NamedThing	retinal cone cell fate determination	The process in which a cell becomes capable of differentiating autonomously into a retinal cone cell regardless of its environment; upon determination, the cell fate cannot be reversed.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0043703	biolink:NamedThing	photoreceptor cell fate determination	The process in which a cell becomes capable of differentiating autonomously into a photoreceptor cell regardless of its environment; upon determination, the cell fate cannot be reversed.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:2000322	biolink:NamedThing	regulation of glucocorticoid receptor signaling pathway	Any process that modulates the frequency, rate or extent of glucocorticoid receptor signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	regulation of glucocorticoid receptor signalling pathway							vk	2011-01-18T04:38:10Z					biological_process											owl:Class	
GO:0102687	biolink:NamedThing	UDP-glucose:dihydrozeatin 7-N-glucosyltransferase activity	Catalysis of the reaction: UDP-alpha-D-glucose + dihydrozeatin <=> H+ + dihydrozeatin-7-N-glucose + UDP.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-4724									molecular_function											owl:Class	
GO:1903177	biolink:NamedThing	negative regulation of tyrosine 3-monooxygenase activity	Any process that stops, prevents or reduces the frequency, rate or extent of tyrosine 3-monooxygenase activity.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of tyrosine 3-hydroxylase activity|down regulation of L-tyrosine hydroxylase activity|inhibition of tyrosine 3-hydroxylase activity|inhibition of tyrosine 3-monooxygenase activity|down-regulation of L-tyrosine hydroxylase activity|down-regulation of tyrosine hydroxylase activity|down-regulation of tyrosine 3-hydroxylase activity|downregulation of tyrosine 3-hydroxylase activity|downregulation of tyrosine hydroxylase activity|down regulation of tyrosine 3-monooxygenase activity|negative regulation of L-tyrosine,tetrahydrobiopterin:oxygen oxidoreductase (3-hydroxylating)|downregulation of L-tyrosine,tetrahydrobiopterin:oxygen oxidoreductase (3-hydroxylating)|inhibition of L-tyrosine,tetrahydrobiopterin:oxygen oxidoreductase (3-hydroxylating)|down-regulation of L-tyrosine,tetrahydrobiopterin:oxygen oxidoreductase (3-hydroxylating)|downregulation of tyrosine 3-monooxygenase activity|negative regulation of tyrosine hydroxylase activity|inhibition of L-tyrosine hydroxylase activity|down regulation of tyrosine hydroxylase activity|down-regulation of tyrosine 3-monooxygenase activity|inhibition of tyrosine hydroxylase activity|down regulation of L-tyrosine,tetrahydrobiopterin:oxygen oxidoreductase (3-hydroxylating)|downregulation of L-tyrosine hydroxylase activity|negative regulation of L-tyrosine hydroxylase activity|down regulation of tyrosine 3-hydroxylase activity							bf	2014-07-14T10:39:15Z					biological_process											owl:Class	
GO:1903176	biolink:NamedThing	regulation of tyrosine 3-monooxygenase activity	Any process that modulates the frequency, rate or extent of tyrosine 3-monooxygenase activity.	tmpzr1t_l9r_go_relaxed.owl	regulation of L-tyrosine,tetrahydrobiopterin:oxygen oxidoreductase (3-hydroxylating)|regulation of L-tyrosine hydroxylase activity|regulation of tyrosine hydroxylase activity|regulation of tyrosine 3-hydroxylase activity							bf	2014-07-14T10:39:09Z					biological_process											owl:Class	
GO:0086096	biolink:NamedThing	adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in heart process	An adrenergic receptor signaling pathway which contributes to a circulatory system process carried out by the heart, where the activated adrenergic receptor transmits the signal by Gi-mediated inhibition of adenylate cyclase activity.	tmpzr1t_l9r_go_relaxed.owl	Gi-coupled adrenergic receptor signaling pathway involved in heart process|cardiac adrenergic receptor signaling pathway via inhibition of adenylate cyclase activity|Gi-coupled Beta2-AR signaling pathway involved in heart process|G-inhibitory-coupled Beta2AR signaling pathway involved in heart process					Although Beta1-adrenergic receptors couple exclusively to the Gs protein, Beta2-adrenergic receptors couple to both Gs and Gi proteins. Coupling to Gi proteins may localize the Gs-mediated signaling.		bf						biological_process											owl:Class	
GO:0071881	biolink:NamedThing	adenylate cyclase-inhibiting adrenergic receptor signaling pathway	The series of molecular signals generated as a consequence of an adrenergic receptor binding to its physiological ligand, where the pathway proceeds with inhibition of adenylyl cyclase and a subsequent decrease in the concentration of cyclic AMP (cAMP).	tmpzr1t_l9r_go_relaxed.owl	adrenergic receptor, adenylate cyclase inhibiting pathway|inhibition of adenylate cyclase activity by adrenergic receptor signalling pathway|inhibition of adenylate cyclase activity by adrenergic receptor signaling pathway|adrenergic receptor, adenylyl cyclase inhibiting pathway							mah	2010-09-13T04:22:53Z					biological_process											owl:Class	
GO:0002542	biolink:NamedThing	Factor XII activation	Any process that activates Factor XII (Hageman factor). Factor XII is a protein synthesized by the liver that circulates in an inactive form until it encounters collagen or basement membrane or activated platelets (as occurs at the site of endothelial injury). Factor XII then undergoes a conformational change (becoming factor XIIa), exposing an active serine center that can subsequently cleave protein substrates and activate a variety of mediator systems. Factor XII is a participant in the clotting cascade as well as the kinin cascade.	tmpzr1t_l9r_go_relaxed.owl	Hageman factor activation													biological_process											owl:Class	
GO:0047162	biolink:NamedThing	17-O-deacetylvindoline O-acetyltransferase activity	Catalysis of the reaction: (1R,9R,10S,11R,12R,19R)-12-ethyl-10,11-dihydroxy-5-methoxy-10-(methoxycarbonyl)-8-methyl-8,16-diazapentacyclo[10.6.1.0^{1,9}.0^{2,7}.0^{16,19}]nonadeca-2(7),3,5,13-tetraen-16-ium + acetyl-CoA = (1R,9R,10S,11R,12R,19R)-11-(acetyloxy)-12-ethyl-10-hydroxy-5-methoxy-10-(methoxycarbonyl)-8-methyl-8,16-diazapentacyclo[10.6.1.0^{1,9}.0^{2,7}.0^{16,19}]nonadeca-2(7),3,5,13-tetraen-16-ium + CoA.	tmpzr1t_l9r_go_relaxed.owl	DAT activity|acetyl-CoA:deacetylvindoline 4-O-acetyltransferase activity|acetylcoenzyme A-deacetylvindoline 4-O-acetyltransferase activity|acetyl-CoA-17-O-deacetylvindoline 17-O-acetyltransferase activity|deacetylvindoline O-acetyltransferase activity|acetylcoenzyme A:deacetylvindoline 4-O-acetyltransferase activity|17-O-deacetylvindoline-17-O-acetyltransferase activity|deacetylvindoline acetyltransferase activity|acetylcoenzyme A:deacetylvindoline O-acetyltransferase activity|acetyl-CoA:17-O-deacetylvindoline 17-O-acetyltransferase activity				RHEA:24496|MetaCyc:2.3.1.107-RXN|EC:2.3.1.107|KEGG_REACTION:R03230									molecular_function											owl:Class	
GO:0070046	biolink:NamedThing	synaptobrevin 2-SNAP-25-syntaxin-3 complex	A SNARE complex that contains synaptobrevin 2 (VAMP2), SNAP-25, and syntaxin 3 (or orthologs thereof).	tmpzr1t_l9r_go_relaxed.owl	SNARE complex (Stx3, Snap25, Vamp2)|Stx3-Snap25-Vamp2 complex													cellular_component											owl:Class	
GO:2001020	biolink:NamedThing	regulation of response to DNA damage stimulus	Any process that modulates the frequency, rate or extent of response to DNA damage stimulus.	tmpzr1t_l9r_go_relaxed.owl	regulation of cellular response to DNA damage stimulus|regulation of cellular DNA damage response|regulation of DNA damage response|regulation of response to genotoxic stress							yaf	2011-08-19T10:20:25Z					biological_process											owl:Class	
GO:0000798	biolink:NamedThing	nuclear cohesin complex	A cohesin complex required for cohesion between sister chromatids that remain in the nucleus.	tmpzr1t_l9r_go_relaxed.owl						Note that this term and its children should be used to annotate gene products found in cohesin complexes in organisms that undergo closed mitosis (i.e. where the nuclear envelope does not break down, as in fungi). For organisms in which the nuclear envelope breaks down during mitosis, the parent should be used.								cellular_component											owl:Class	
GO:1902484	biolink:NamedThing	Sertoli cell apoptotic process	Any apoptotic process in a Sertoli cell.	tmpzr1t_l9r_go_relaxed.owl	Sertoli cell apoptosis							pr	2013-11-06T11:27:34Z					biological_process											owl:Class	
GO:1904019	biolink:NamedThing	epithelial cell apoptotic process	Any apoptotic process in an epithelial cell.	tmpzr1t_l9r_go_relaxed.owl	epitheliocyte apoptosis|epitheliocyte apoptotic process|epithelial cell apoptosis							sl	2015-03-06T22:27:17Z					biological_process											owl:Class	
GO:0046375	biolink:NamedThing	K antigen metabolic process	The chemical reactions and pathways involving K antigen, a capsular polysaccharide antigen carried on the surface of bacterial capsules that masks somatic (O) antigens.	tmpzr1t_l9r_go_relaxed.owl	K antigen metabolism													biological_process											owl:Class	
GO:1990074	biolink:NamedThing	polyuridylation-dependent mRNA catabolic process	The chemical reactions and pathways resulting in the breakdown of a messenger RNA (mRNA) molecule, initiated by the enzymatic addition of a sequence of uridylyl residues (polyuridylation) at the 3' end of the target mRNA.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/20568						tb	2013-04-16T22:51:46Z					biological_process											owl:Class	
GO:0034620	biolink:NamedThing	cellular response to unfolded protein	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an unfolded protein stimulus.	tmpzr1t_l9r_go_relaxed.owl	heat shock protein activity					Note that this term should not be confused with 'unfolded protein response ; GO:0030968', which refers to the signaling pathways that respond to the presence of unfolded proteins in the ER.								biological_process											owl:Class	
GO:0006986	biolink:NamedThing	response to unfolded protein	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an unfolded protein stimulus.	tmpzr1t_l9r_go_relaxed.owl	heat shock protein activity					Note that this term should not be confused with 'unfolded protein response ; GO:0030968', which refers to one specific response to the presence of unfolded proteins in the ER.								biological_process											owl:Class	
GO:0099646	biolink:NamedThing	neurotransmitter receptor transport, plasma membrane to endosome	Vesicle-mediated transport of a neurotransmitter receptor vesicle from the plasma membrane to the endosome.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0036010	biolink:NamedThing	protein localization to endosome	A process in which a protein is transported to, or maintained in, a location within an endosome.	tmpzr1t_l9r_go_relaxed.owl	protein localisation in endosome|protein localization in endosome							bf	2011-10-06T02:42:18Z					biological_process											owl:Class	
GO:0003143	biolink:NamedThing	embryonic heart tube morphogenesis	The process in which the anatomical structures of the embryonic heart tube are generated and organized. The embryonic heart tube is an epithelial tube that will give rise to the mature heart.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-09-22T04:21:17Z					biological_process											owl:Class	
GO:0004112	biolink:NamedThing	cyclic-nucleotide phosphodiesterase activity	Catalysis of the reaction: a nucleoside cyclic phosphate + H2O = a nucleoside phosphate.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0005935	biolink:NamedThing	cellular bud neck	The constriction between the mother cell and daughter cell (bud) in an organism that reproduces by budding.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0015371	biolink:NamedThing	galactose:sodium symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: galactose(out) + Na+(out) = glucose(in) + Na+(in).	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1901978	biolink:NamedThing	positive regulation of cell cycle checkpoint	Any process that activates or increases the frequency, rate or extent of cell cycle checkpoint.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of G1/S transition checkpoint|activation of cell cycle checkpoint|up regulation of cell cycle checkpoint|upregulation of cell cycle checkpoint|positive regulation of G1/S checkpoint|up-regulation of cell cycle checkpoint							jl	2013-03-06T15:10:34Z			GO:2001052		biological_process											owl:Class	
GO:0048677	biolink:NamedThing	axon extension involved in regeneration	Long distance growth of a single axon process involved in regeneration of the neuron.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0090310	biolink:NamedThing	negative regulation of DNA methylation-dependent heterochromatin assembly	Any process that decreases the rate, frequency, or extent of the repression of transcription by methylation of DNA, leading to the formation of heterochromatin.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of methylation-dependent chromatin silencing							tb	2010-04-09T02:12:53Z					biological_process											owl:Class	
GO:1900675	biolink:NamedThing	regulation of F-9775B biosynthetic process	Any process that modulates the frequency, rate or extent of F-9775B biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of F-9775B formation|regulation of F-9775B anabolism|regulation of F-9775B biosynthesis|regulation of F-9775B synthesis							di	2012-05-22T04:26:31Z					biological_process											owl:Class	
GO:1900732	biolink:NamedThing	regulation of polyketide biosynthetic process	Any process that modulates the frequency, rate or extent of polyketide biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of polyketide anabolism|regulation of polyketide formation|regulation of polyketide biosynthesis|regulation of polyketide synthesis							di	2012-05-26T01:29:40Z					biological_process											owl:Class	
GO:2000937	biolink:NamedThing	negative regulation of cellotriose catabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of cellotriose catabolic process.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of cellotriose catabolism							tt	2011-08-01T12:45:31Z					biological_process											owl:Class	
GO:0046076	biolink:NamedThing	dTTP catabolic process	The chemical reactions and pathways resulting in the breakdown of dTTP, deoxyribosylthymine triphosphate.	tmpzr1t_l9r_go_relaxed.owl	dTTP breakdown|dTTP degradation|dTTP catabolism													biological_process											owl:Class	
GO:0009213	biolink:NamedThing	pyrimidine deoxyribonucleoside triphosphate catabolic process	The chemical reactions and pathways resulting in the breakdown of pyrimidine deoxyribonucleoside triphosphate, a compound consisting of a pyrimidine base linked to a deoxyribose sugar esterified with triphosphate on the sugar.	tmpzr1t_l9r_go_relaxed.owl	pyrimidine deoxyribonucleoside triphosphate breakdown|pyrimidine deoxyribonucleoside triphosphate catabolism|pyrimidine deoxyribonucleoside triphosphate degradation													biological_process											owl:Class	
GO:1904345	biolink:NamedThing	negative regulation of gastric mucosal blood circulation	Any process that stops, prevents or reduces the frequency, rate or extent of gastric mucosal blood circulation.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of gastric mucosal blood circulation|downregulation of gastric mucosal blood circulation|down regulation of gastric mucosal blood circulation|down regulation of stomach mucosal blood circulation|downregulation of stomach mucosal blood circulation|inhibition of stomach mucosal blood circulation|down-regulation of stomach mucosal blood circulation|negative regulation of stomach mucosal blood circulation|inhibition of gastric mucosal blood circulation							sl	2015-06-11T21:20:44Z					biological_process											owl:Class	
GO:0051895	biolink:NamedThing	negative regulation of focal adhesion assembly	Any process that stops, prevents, or reduces the frequency, rate or extent of focal adhesion assembly, the establishment and maturation of focal adhesions.	tmpzr1t_l9r_go_relaxed.owl	downregulation of focal adhesion formation|inhibition of focal adhesion formation|down regulation of focal adhesion formation|down-regulation of focal adhesion formation													biological_process											owl:Class	
GO:0051893	biolink:NamedThing	regulation of focal adhesion assembly	Any process that modulates the frequency, rate or extent of focal adhesion formation, the establishment and maturation of focal adhesions.	tmpzr1t_l9r_go_relaxed.owl	regulation of adhesion plaque assembly													biological_process											owl:Class	
GO:0080148	biolink:NamedThing	negative regulation of response to water deprivation	Any process that stops, prevents, or reduces the frequency, rate or extent of a response to water deprivation. Response to water deprivation is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a water deprivation stimulus, prolonged deprivation of water.	tmpzr1t_l9r_go_relaxed.owl								dhl	2010-03-26T01:58:11Z					biological_process											owl:Class	
GO:0043161	biolink:NamedThing	proteasome-mediated ubiquitin-dependent protein catabolic process	The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome.	tmpzr1t_l9r_go_relaxed.owl	proteasomal ubiquitin-dependent protein catabolism|proteasomal pathway|proteasomal ubiquitin-dependent protein degradation|proteasomal ubiquitin-dependent protein breakdown|proteasomal processing|proteasomal ubiquitin-dependent protein catabolic process|proteasome pathway													biological_process											owl:Class	
GO:0018625	biolink:NamedThing	naphthalene 1,2-dioxygenase activity	Catalysis of the reaction: naphthalene + NADH + H+ + O2 = (1R,2S)-1,2-dihydronaphthalene-1,2-diol + NAD+.	tmpzr1t_l9r_go_relaxed.owl	naphthalene oxygenase activity|naphthalene,NADH:oxygen oxidoreductase (1,2-hydroxylating)|naphthalene dioxygenase activity				MetaCyc:NAPHTHALENE-12-DIOXYGENASE-RXN|RHEA:19173|EC:1.14.12.12|UM-BBD_enzymeID:e0002									molecular_function											owl:Class	
GO:0045119	biolink:NamedThing	azole:proton antiporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + azole(in) = H+(in) + azole(out). Azoles are heterocyclic compounds found in many biologically important substances.	tmpzr1t_l9r_go_relaxed.owl	azole:hydrogen antiporter activity|bicyclomycin/sulfathiazole:hydrogen antiporter activity													molecular_function											owl:Class	
GO:0046099	biolink:NamedThing	guanine biosynthetic process	The chemical reactions and pathways resulting in the formation of guanine, 2-amino-6-hydroxypurine, a purine that is one of the five main bases found in nucleic acids and a component of a number of phosphorylated guanosine derivatives whose metabolic or regulatory functions are important.	tmpzr1t_l9r_go_relaxed.owl	guanine biosynthesis|guanine formation|guanine anabolism|guanine synthesis													biological_process											owl:Class	
GO:0009113	biolink:NamedThing	purine nucleobase biosynthetic process	The chemical reactions and pathways resulting in the formation of purine nucleobases, one of the two classes of nitrogen-containing ring compounds found in DNA and RNA, which include adenine and guanine.	tmpzr1t_l9r_go_relaxed.owl	purine base anabolism|purine base formation|purine base biosynthesis|purine base synthesis|purine base biosynthetic process				MetaCyc:PWY-841									biological_process											owl:Class	
GO:0072336	biolink:NamedThing	negative regulation of canonical Wnt signaling pathway involved in neural crest cell differentiation	Any process that decreases the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin involved in neural crest cell differentiation. The Wnt signaling pathway is the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of Wnt receptor signaling pathway through beta-catenin involved in neural crest cell differentiation|negative regulation of canonical Wnt receptor signaling pathway involved in neural crest cell differentiation|negative regulation of canonical Wnt receptor signalling pathway involved in neural crest cell differentiation|negative regulation of canonical Wnt-activated signaling pathway involved in neural crest cell differentiation							mah	2010-11-03T03:16:10Z					biological_process											owl:Class	
GO:0090090	biolink:NamedThing	negative regulation of canonical Wnt signaling pathway	Any process that decreases the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin, the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of canonical Wnt receptor signalling pathway|negative regulation of canonical Wnt-activated signaling pathway|negative regulation of catenin protein nuclear translocation|negative regulation of catenin import into nucleus|negative regulation of canonical Wnt receptor signaling pathway|negative regulation of Wnt receptor signaling pathway through beta-catenin							tb	2009-10-30T11:27:17Z			GO:0035414		biological_process											owl:Class	
GO:0008074	biolink:NamedThing	guanylate cyclase complex, soluble	Complex that possesses guanylate cyclase activity and is not bound to a membrane.	tmpzr1t_l9r_go_relaxed.owl						See also the molecular function term 'guanylate cyclase activity ; GO:0004383'.								cellular_component											owl:Class	
GO:0018677	biolink:NamedThing	pentachlorophenol monooxygenase activity	Catalysis of the reaction: pentachlorophenol + NADPH + H+ + O2 = tetrachlorohydroquinone + NADP+ + chloride.	tmpzr1t_l9r_go_relaxed.owl	pentachlorophenol dechlorinase activity|pentachlorophenol hydroxylase activity|PcpB|PCB4MO activity|PCB 4-monooxygenase activity|PCP hydroxylase activity|pentachlorophenol 4-monooxygenase activity|pentachlorophenol dehalogenase activity|pentachlorophenol,NADPH:oxygen oxidoreductase (hydroxylating, dechlorinating)				EC:1.14.13.50|UM-BBD_enzymeID:e0148|RHEA:18685|MetaCyc:PCP4MONO-RXN									molecular_function											owl:Class	
GO:0035323	biolink:NamedThing	male germline ring canal	An intercellular bridge that connects the germline cells of a male cyst.	tmpzr1t_l9r_go_relaxed.owl	testicular ring canal|spermatocyte ring canal							bf	2010-02-25T11:05:14Z					cellular_component											owl:Class	
GO:0045172	biolink:NamedThing	germline ring canal	Germline specific intercellular bridge. During cyst formation in insects, ring canals interconnect the cells of the cyst, facilitating the passage of cytoplasmic components between cells.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0015445	biolink:NamedThing	P-type silver transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Ag+(in) -> ADP + phosphate + Ag+(out).	tmpzr1t_l9r_go_relaxed.owl	silver exporting ATPase activity|ATP phosphohydrolase (Ag+-exporting)|Ag+-exporting ATPase activity|silver-exporting ATPase activity|silver transmembrane transporter activity, phosphorylative mechanism				MetaCyc:3.6.3.53-RXN|RHEA:14733|EC:7.2.2.15									molecular_function											owl:Class	
GO:0015080	biolink:NamedThing	silver ion transmembrane transporter activity	Enables the transfer of silver (Ag) ions from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	silver transporter activity													molecular_function											owl:Class	
GO:0004822	biolink:NamedThing	isoleucine-tRNA ligase activity	Catalysis of the reaction: L-isoleucine + ATP + tRNA(Ile) = L-isoleucyl-tRNA(Ile) + AMP + diphosphate + 2 H(+).	tmpzr1t_l9r_go_relaxed.owl	isoleucine translase activity|isoleucyl-tRNA synthetase activity|isoleucyl-transfer ribonucleate synthetase activity|isoleucine-transfer RNA ligase activity|isoleucyl-transfer RNA synthetase activity|L-isoleucine:tRNAIle ligase (AMP-forming)|isoleucine-tRNA synthetase activity				Reactome:R-HSA-379893|EC:6.1.1.5|KEGG_REACTION:R03656|Reactome:R-HSA-380176|RHEA:11060|MetaCyc:ISOLEUCINE--TRNA-LIGASE-RXN									molecular_function											owl:Class	
GO:0009322	biolink:NamedThing	trimethylamine-N-oxide reductase complex	An enzyme complex that catalyzes the reduction of trimethylamine N-oxide to trimethylamine.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0072720	biolink:NamedThing	response to dithiothreitol	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dithiothreitol stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to DTT|response to 1,4-dithiothreitol							mah	2012-05-09T11:08:58Z					biological_process											owl:Class	
GO:1901548	biolink:NamedThing	positive regulation of synaptic vesicle lumen acidification	Any process that activates or increases the frequency, rate or extent of synaptic vesicle lumen acidification.	tmpzr1t_l9r_go_relaxed.owl	upregulation of synaptic vesicle lumen pH reduction|up-regulation of synaptic vesicle lumen acidification|up-regulation of synaptic vesicle lumen pH reduction|positive regulation of proton loading|activation of synaptic vesicle lumen acidification|upregulation of synaptic vesicle lumen acidification|positive regulation of synaptic vesicle lumen pH reduction|activation of synaptic vesicle lumen pH reduction|up regulation of synaptic vesicle lumen pH reduction|up regulation of synaptic vesicle lumen acidification							dsf	2012-10-26T16:09:32Z					biological_process											owl:Class	
GO:0002336	biolink:NamedThing	B-1 B cell lineage commitment	The process in which an immature B cell becomes committed to become a B-1 B cell.	tmpzr1t_l9r_go_relaxed.owl	B-1 B-lymphocyte lineage commitment|B-1 B-cell lineage commitment|B-1 B lymphocyte lineage commitment													biological_process											owl:Class	
GO:0002326	biolink:NamedThing	B cell lineage commitment	The process in which a lymphoid progenitor cell becomes committed to become any type of B cell.	tmpzr1t_l9r_go_relaxed.owl	B-lymphocyte lineage commitment|B-cell lineage commitment|B lymphocyte lineage commitment													biological_process											owl:Class	
GO:1900126	biolink:NamedThing	negative regulation of hyaluronan biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of hyaluronan biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	downregulation of hyaluronan anabolism|down regulation of hyaluronan formation|downregulation of hyaluronan biosynthesis|downregulation of hyaluronan synthesis|down-regulation of hyaluronan biosynthetic process|negative regulation of hyaluronan formation|down-regulation of hyaluronan synthesis|down regulation of hyaluronan biosynthesis|inhibition of hyaluronan formation|negative regulation of hyaluronan synthesis|inhibition of hyaluronan biosynthesis|inhibition of hyaluronan synthesis|down-regulation of hyaluronan biosynthesis|downregulation of hyaluronan biosynthetic process|down regulation of hyaluronan anabolism|down-regulation of hyaluronan formation|negative regulation of hyaluronan anabolism|down regulation of hyaluronan biosynthetic process|inhibition of hyaluronan biosynthetic process|down regulation of hyaluronan synthesis|down-regulation of hyaluronan anabolism|inhibition of hyaluronan anabolism|negative regulation of hyaluronan biosynthesis|downregulation of hyaluronan formation							yaf	2012-02-23T01:09:29Z					biological_process											owl:Class	
GO:0010558	biolink:NamedThing	negative regulation of macromolecule biosynthetic process	Any process that decreases the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1903672	biolink:NamedThing	positive regulation of sprouting angiogenesis	Any process that activates or increases the frequency, rate or extent of sprouting angiogenesis.	tmpzr1t_l9r_go_relaxed.owl	activation of sprouting angiogenesis|upregulation of sprouting angiogenesis|up regulation of sprouting angiogenesis|up-regulation of sprouting angiogenesis							pga	2014-11-27T10:11:08Z					biological_process											owl:Class	
GO:2000184	biolink:NamedThing	positive regulation of progesterone biosynthetic process	Any process that activates or increases the frequency, rate or extent of progesterone biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of progesterone synthesis|positive regulation of progesterone anabolism|positive regulation of progesterone formation|positive regulation of progesterone biosynthesis							dph	2010-10-14T07:36:14Z					biological_process											owl:Class	
GO:0034063	biolink:NamedThing	stress granule assembly	The aggregation, arrangement and bonding together of proteins and RNA molecules to form a stress granule.	tmpzr1t_l9r_go_relaxed.owl	SG assembly													biological_process											owl:Class	
GO:0035359	biolink:NamedThing	negative regulation of peroxisome proliferator activated receptor signaling pathway	Any process that stops, prevents, or reduces the frequency, rate or extent of the peroxisome proliferator activated receptor signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of peroxisome proliferator-activated receptor signaling pathway|negative regulation of PPAR signaling pathway|negative regulation of peroxisome proliferator activated receptor signalling pathway							bf	2010-03-05T10:41:35Z					biological_process											owl:Class	
GO:0060663	biolink:NamedThing	apoptotic process involved in salivary gland cavitation	Any apoptotic process in which the solid core of the gland is hollowed out to form the duct.	tmpzr1t_l9r_go_relaxed.owl	apoptosis involved in salivary gland cavitation							dph	2009-06-01T08:27:16Z					biological_process											owl:Class	
GO:0060609	biolink:NamedThing	apoptotic process involved in tube lumen cavitation	Any apoptotic process that contributes to the hollowing out of an epithelial rod or cord to form the central hole in a tube.	tmpzr1t_l9r_go_relaxed.owl	apoptosis involved in tube lumen cavitation							dph	2009-05-15T10:05:39Z					biological_process											owl:Class	
GO:1902926	biolink:NamedThing	inulin metabolic process	The chemical reactions and pathways involving inulin.	tmpzr1t_l9r_go_relaxed.owl	inulin metabolism					SUC2 in S. cerevisiae strain JZ1C in PMID:23104410.		se	2014-04-21T23:54:33Z					biological_process											owl:Class	
GO:1905144	biolink:NamedThing	response to acetylcholine	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acetylcholine stimulus.	tmpzr1t_l9r_go_relaxed.owl								dos	2016-04-14T08:54:49Z					biological_process											owl:Class	
GO:0099618	biolink:NamedThing	UDP-glucuronic acid dehydrogenase activity	Catalysis of the reaction: UDP-glucuronate + NAD+ = UDP-beta-L-threo-pentapyranos-4-ulose + CO2 + NADH + H+.	tmpzr1t_l9r_go_relaxed.owl	UDP-GlcUA decarboxylase activity				EC:1.1.1.305|RHEA:24702									molecular_function											owl:Class	
GO:0070281	biolink:NamedThing	pyridoxamine binding	Binding to pyridoxamine, 4-(aminomethyl)-5-(hydroxymethyl)-2-methylpyridin-3-ol, a form of vitamin B6.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0061704	biolink:NamedThing	glycolytic process from sucrose	The chemical reactions and pathways resulting in the breakdown of a sucrose into pyruvate, with the concomitant production of a small amount of ATP and the reduction of NAD(P) to NAD(P)H. Glycolysis begins with the metabolism of a carbohydrate to generate products that can enter the pathway and ends with the production of pyruvate. Pyruvate may be converted to acetyl-coenzyme A, ethanol, lactate, or other small molecules.	tmpzr1t_l9r_go_relaxed.owl								dph	2015-06-11T13:26:28Z					biological_process											owl:Class	
GO:0005614	biolink:NamedThing	interstitial matrix	A type of extracellular matrix found in interstitial connective tissue, characterized by the presence of fibronectins, proteoglycans, and types I, III, V, VI, VII and XII collagens.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0030979	biolink:NamedThing	alpha-glucan biosynthetic process	The chemical reactions and pathways resulting in the formation of alpha-glucans, compounds composed of glucose residues linked by alpha-D-glucosidic bonds.	tmpzr1t_l9r_go_relaxed.owl	alpha-glucan anabolism|alpha-glucan biosynthesis|alpha-glucan synthesis|alpha-glucan formation													biological_process											owl:Class	
GO:0030662	biolink:NamedThing	coated vesicle membrane	The lipid bilayer surrounding a coated vesicle.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0042388	biolink:NamedThing	gibberellic acid mediated signaling pathway, G-alpha-dependent	A series of molecular signals mediated by the detection of gibberellic acid and dependent on the coupling of the alpha subunit of G proteins to the hormone receptors.	tmpzr1t_l9r_go_relaxed.owl	gibberellic acid mediated signalling, G-alpha-dependent													biological_process											owl:Class	
GO:0050244	biolink:NamedThing	pyruvate oxidase (CoA-acetylating) activity	Catalysis of the reaction: CoA + H(+) + O(2) + pyruvate = acetyl-CoA + CO(2) + H(2)O(2).	tmpzr1t_l9r_go_relaxed.owl	pyruvate:oxygen 2-oxidoreductase (CoA-acetylating)				MetaCyc:PYRUVATE-OXIDASE-COA-ACETYLATING-RXN|EC:1.2.3.6|KEGG_REACTION:R00211|RHEA:21912									molecular_function											owl:Class	
GO:0010168	biolink:NamedThing	ER body	A novel compartment found in plant cells that is derived from the ER. The structures have a characteristic shape and size (10 mm long and 0.5 mm wide) and are surrounded with ribosomes. They have been found in Arabidopsis thaliana and related Brassicaceae species.	tmpzr1t_l9r_go_relaxed.owl	endoplasmic reticulum body													cellular_component											owl:Class	
GO:0034156	biolink:NamedThing	negative regulation of toll-like receptor 7 signaling pathway	Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 7 signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of toll-like receptor 7 signalling pathway|negative regulation of TLR7 signaling pathway													biological_process											owl:Class	
GO:0034155	biolink:NamedThing	regulation of toll-like receptor 7 signaling pathway	Any process that modulates the frequency, rate, or extent of toll-like receptor 7 signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	regulation of TLR7 signaling pathway|regulation of toll-like receptor 7 signalling pathway													biological_process											owl:Class	
GO:1903450	biolink:NamedThing	regulation of G1 to G0 transition	Any process that modulates the frequency, rate or extent of G1 to G0 transition.	tmpzr1t_l9r_go_relaxed.owl	regulation of cell cycle quiescence|regulation of stationary phase|regulation of G1/G0 transition|regulation of establishment of cell quiescence							di	2014-09-19T22:23:13Z					biological_process											owl:Class	
GO:0106111	biolink:NamedThing	regulation of mitotic cohesin ssDNA (lagging strand) loading	Any process that modulates the frequency, rate or extent of mitotic cohesin ssDNA (lagging strand) loading.	tmpzr1t_l9r_go_relaxed.owl								hjd	2018-04-18T14:36:47Z					biological_process											owl:Class	
GO:0018178	biolink:NamedThing	peptidyl-threonine adenylylation	The adenylylation of peptidyl-threonine to form peptidyl-O-(phospho-5'-adenosine)-L-threonine.	tmpzr1t_l9r_go_relaxed.owl	peptidyl-threonine adenylation				RESID:AA0267									biological_process											owl:Class	
GO:0018117	biolink:NamedThing	protein adenylylation	The addition of an adenylyl group (adenosine 5'-monophosphate; AMP) to a protein amino acid.	tmpzr1t_l9r_go_relaxed.owl	protein AMPylation|protein adenylation|protein amino acid adenylylation											GO:0018176		biological_process											owl:Class	
GO:0019468	biolink:NamedThing	nopaline catabolic process	The chemical reactions and pathways resulting in the breakdown of nopaline (N-(I-carboxy-4-guanidinobutyl)glutamic acid), a rare amino-acid derivative.	tmpzr1t_l9r_go_relaxed.owl	nopaline breakdown|nopaline degradation|nopaline catabolism				MetaCyc:NOPALINEDEG-PWY									biological_process											owl:Class	
GO:2001114	biolink:NamedThing	positive regulation of cellular response to hepatocyte growth factor stimulus	Any process that activates or increases the frequency, rate or extent of cellular response to hepatocyte growth factor stimulus.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of cellular response to HGF stimulus							dph	2011-10-05T05:43:26Z					biological_process											owl:Class	
GO:0004490	biolink:NamedThing	methylglutaconyl-CoA hydratase activity	Catalysis of the reaction: (S)-3-hydroxy-3-methylglutaryl-CoA = trans-3-methylglutaconyl-CoA + H(2)O.	tmpzr1t_l9r_go_relaxed.owl	methylglutaconase activity|(S)-3-hydroxy-3-methylglutaryl-CoA hydro-lyase activity|(S)-3-hydroxy-3-methylglutaryl-CoA hydro-lyase (trans-3-methylglutaconyl-CoA-forming)|methylglutaconyl coenzyme A hydratase activity|3-methylglutaconyl CoA hydratase activity				KEGG_REACTION:R02085|EC:4.2.1.18|MetaCyc:METHYLGLUTACONYL-COA-HYDRATASE-RXN|RHEA:21536|Reactome:R-HSA-70785									molecular_function											owl:Class	
GO:1902181	biolink:NamedThing	verruculogen biosynthetic process	The chemical reactions and pathways resulting in the formation of verruculogen.	tmpzr1t_l9r_go_relaxed.owl	verruculogen synthesis|verruculogen anabolism|verruculogen formation|verruculogen biosynthesis							di	2013-05-30T17:44:35Z					biological_process											owl:Class	
GO:0008964	biolink:NamedThing	phosphoenolpyruvate carboxylase activity	Catalysis of the reaction: phosphate + oxaloacetate = phosphoenolpyruvate + HCO3-.	tmpzr1t_l9r_go_relaxed.owl	PEPCase activity|phosphopyruvate (phosphate) carboxylase activity|phosphate:oxaloacetate carboxy-lyase (adding phosphate; phosphoenolpyruvate-forming)|PEPC|phosphoenolpyruvic carboxylase activity|phosphate:oxaloacetate carboxy-lyase (phosphorylating)|PEP carboxylase activity				KEGG_REACTION:R00345|MetaCyc:PEPCARBOX-RXN|EC:4.1.1.31|RHEA:28370									molecular_function											owl:Class	
GO:0004611	biolink:NamedThing	phosphoenolpyruvate carboxykinase activity	Catalysis of the reaction: source of phosphate + oxaloacetate = phosphoenolpyruvate + CO2 + other reaction products.	tmpzr1t_l9r_go_relaxed.owl	PEP carboxykinase activity|phosphopyruvate carboxylase activity|PEPCK activity				EC:4.1.1.32									molecular_function											owl:Class	
GO:0034268	biolink:NamedThing	discadenine biosynthetic process	The chemical reactions and pathways resulting in the formation of discadenine, (2S)-2-amino-4-{6-[(3-methylbut-2-en-1-yl)amino]-3H-purin-3-yl}butanoic acid.	tmpzr1t_l9r_go_relaxed.owl	discadenine formation|discadenine anabolism|discadenine biosynthesis|discadenine synthesis													biological_process											owl:Class	
GO:1901241	biolink:NamedThing	4-hydroxyphenylacetate transmembrane transporter activity	Enables the transfer of 4-hydroxyphenylacetate from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl					RHEA:33175			jl	2012-08-07T15:09:49Z					molecular_function											owl:Class	
GO:0002769	biolink:NamedThing	natural killer cell inhibitory signaling pathway	A series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of a natural killer cell capable of inhibiting an immune effector process contributing to an immune response.	tmpzr1t_l9r_go_relaxed.owl	natural killer cell inhibitory signalling pathway|Ly49 inhibitory receptor signaling pathway|inhibitory KIR signaling pathway|NK cell inhibitory signaling pathway|killer cell inhibitory receptor signaling pathway													biological_process											owl:Class	
GO:0015322	biolink:NamedThing	secondary active oligopeptide transmembrane transporter activity	Enables the transfer of an oligopeptide or oligopeptides from one side of a membrane to the other, up the solute's concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction.	tmpzr1t_l9r_go_relaxed.owl	oligopeptide porter activity													molecular_function											owl:Class	
GO:1900500	biolink:NamedThing	regulation of butyryl-CoA catabolic process to butyrate	Any process that modulates the frequency, rate or extent of butyryl-CoA catabolic process to butyrate.	tmpzr1t_l9r_go_relaxed.owl	regulation of butyryl-CoA catabolism to butyrate							tt	2012-05-02T03:56:19Z					biological_process											owl:Class	
GO:0030650	biolink:NamedThing	peptide antibiotic metabolic process	The chemical reactions and pathways involving peptides with antibiotic activity.	tmpzr1t_l9r_go_relaxed.owl	peptide antibiotic metabolism													biological_process											owl:Class	
GO:0006518	biolink:NamedThing	peptide metabolic process	The chemical reactions and pathways involving peptides, compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another.	tmpzr1t_l9r_go_relaxed.owl	peptide metabolism													biological_process											owl:Class	
GO:0018124	biolink:NamedThing	peptide cross-linking via 5'-(N6-L-lysine)-L-topaquinone	The cross-linking of the epsilon-amino group of a peptidyl-lysine with peptidyl-topaquinone, a modified tyrosine residue.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0233									biological_process											owl:Class	
GO:0009210	biolink:NamedThing	pyrimidine ribonucleoside triphosphate catabolic process	The chemical reactions and pathways resulting in the breakdown of pyrimidine ribonucleoside triphosphate, a compound consisting of a pyrimidine base linked to a ribose sugar esterified with triphosphate on the sugar.	tmpzr1t_l9r_go_relaxed.owl	pyrimidine ribonucleoside triphosphate catabolism|pyrimidine ribonucleoside triphosphate breakdown|pyrimidine ribonucleoside triphosphate degradation													biological_process											owl:Class	
GO:0009203	biolink:NamedThing	ribonucleoside triphosphate catabolic process	The chemical reactions and pathways resulting in the breakdown of a ribonucleoside triphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with triphosphate on the sugar.	tmpzr1t_l9r_go_relaxed.owl	ribonucleoside triphosphate breakdown|ribonucleoside triphosphate catabolism|ribonucleoside triphosphate degradation													biological_process											owl:Class	
GO:0046344	biolink:NamedThing	ecdysteroid catabolic process	The chemical reactions and pathways resulting in the breakdown of ecdysteroids, a group of polyhydroxylated ketosteroids which initiate post-embryonic development.	tmpzr1t_l9r_go_relaxed.owl	ecdysteroid breakdown|ecdysteroid degradation|ecdysteroid catabolism													biological_process											owl:Class	
GO:0032265	biolink:NamedThing	XMP salvage	Any process which produces xanthosine monophosphate from derivatives of it, without de novo synthesis.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0106380	biolink:NamedThing	purine ribonucleotide salvage	Any process which produces a purine ribonucleotide from derivatives of it, without de novo synthesis.	tmpzr1t_l9r_go_relaxed.owl								hjd	2021-06-11T14:06:34Z					biological_process											owl:Class	
GO:1900463	biolink:NamedThing	negative regulation of cellular response to alkaline pH by negative regulation of transcription from RNA polymerase II promoter	Any process that stops, prevents, or reduces the frequency, rate or extent of cellular response to alkalinity by stopping, preventing, or reducing the frequency, rate or extent of transcription from an RNA polymerase II promoter.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of cellular response to basic pH by negative regulation of transcription from RNA polymerase II promoter|negative regulation of cellular response to alkalinity by negative regulation of transcription from RNA polymerase II promoter							dgf	2012-05-01T07:22:50Z					biological_process											owl:Class	
GO:0000122	biolink:NamedThing	negative regulation of transcription by RNA polymerase II	Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of gene-specific transcription from RNA polymerase II promoter|negative regulation of transcription from Pol II promoter|down regulation of global transcription from RNA polymerase II promoter|down regulation of transcription from RNA polymerase II promoter|downregulation of global transcription from RNA polymerase II promoter|downregulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter, global|down-regulation of global transcription from RNA polymerase II promoter|inhibition of transcription from RNA polymerase II promoter|down-regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|inhibition of global transcription from RNA polymerase II promoter|negative regulation of global transcription from Pol II promoter											GO:0045816|GO:0010553		biological_process											owl:Class	
GO:1905639	biolink:NamedThing	positive regulation of mitochondrial mRNA catabolic process	Any process that activates or increases the frequency, rate or extent of mitochondrial mRNA catabolic process.	tmpzr1t_l9r_go_relaxed.owl	upregulation of mitochondrial mRNA catabolic process|activation of mitochondrial mRNA catabolic process|up regulation of mitochondrial mRNA catabolic process|up-regulation of mitochondrial mRNA catabolic process							tb	2016-11-03T20:24:13Z					biological_process											owl:Class	
GO:0070445	biolink:NamedThing	regulation of oligodendrocyte progenitor proliferation	Any process that modulates the frequency, rate or extent of oligodendrocyte progenitor proliferation.	tmpzr1t_l9r_go_relaxed.owl	regulation of oligodendrocyte precursor proliferation													biological_process											owl:Class	
GO:0042851	biolink:NamedThing	L-alanine metabolic process	The chemical reactions and pathways involving L-alanine, the L-enantiomer of 2-aminopropanoic acid, i.e. (2S)-2-aminopropanoic acid.	tmpzr1t_l9r_go_relaxed.owl	L-alanine metabolism													biological_process											owl:Class	
GO:0006522	biolink:NamedThing	alanine metabolic process	The chemical reactions and pathways involving alanine, 2-aminopropanoic acid.	tmpzr1t_l9r_go_relaxed.owl	alanine metabolism													biological_process											owl:Class	
GO:0048399	biolink:NamedThing	regulation of intermediate mesodermal cell fate specification	Any process that modulates the frequency, rate or extent of intermediate mesoderm cell fate specification.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0042661	biolink:NamedThing	regulation of mesodermal cell fate specification	Any process that modulates the frequency, rate or extent of mesoderm cell fate specification.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1903376	biolink:NamedThing	regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway	Any process that modulates the frequency, rate or extent of oxidative stress-induced neuron intrinsic apoptotic signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	regulation of neuron apoptosis in response to oxidative stress|regulation of neuron intrinsic apoptotic signaling pathway in response to oxidative stress|regulation of oxidative stress-induced neuronal apoptosis|regulation of oxidative stress-induced neuron apoptosis							bf	2014-08-26T13:03:13Z					biological_process											owl:Class	
GO:0050316	biolink:NamedThing	T2-induced deoxynucleotide kinase activity	Catalysis of the reactions: ATP + dGMP = ADP + dGDP, and ATP + dTMP = ADP + dTDP.	tmpzr1t_l9r_go_relaxed.owl	ATP:(d)NMP phosphotransferase activity				EC:2.7.4.12|MetaCyc:GMKALT-RXN|RHEA:12697									molecular_function											owl:Class	
GO:0038136	biolink:NamedThing	ERBB3-ERBB4 signaling pathway	A series of molecular signals transmitted by a heterodimeric complex of the tyrosine kinase receptors ERBB3 and ERBB4. The pathway begins with binding of a ligand to either cell surface receptor, or the dimeric receptor complex, and ends with regulation of a downstream cellular process, e.g. transcription.	tmpzr1t_l9r_go_relaxed.owl	HER3-HER4 signaling pathway|ERBB3-ERBB4 signalling pathway							bf	2012-03-30T11:21:19Z					biological_process											owl:Class	
GO:0038130	biolink:NamedThing	ERBB4 signaling pathway	A series of molecular signals initiated by binding of a ligand to the tyrosine kinase receptor ERBB4 on the surface of a cell. The pathway ends with regulation of a downstream cellular process, e.g. transcription.	tmpzr1t_l9r_go_relaxed.owl	ERBB4 signalling pathway|HER4 signaling pathway|receptor tyrosine-protein kinase erbB-4 signaling pathway							bf	2012-03-30T10:44:08Z					biological_process											owl:Class	
GO:0007552	biolink:NamedThing	metamorphosis	A biological process in which an animal physically develops after birth or hatching, involving a conspicuous and relatively abrupt change in the animal's form or structure. Examples include the change from tadpole to frog, and the change from larva to adult. An example of this is found in Drosophila melanogaster.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Metamorphosis							GO:0046699|GO:0046698		biological_process											owl:Class	
GO:1904292	biolink:NamedThing	regulation of ERAD pathway	Any process that modulates the frequency, rate or extent of ERAD pathway.	tmpzr1t_l9r_go_relaxed.owl	regulation of ER-associated degradation pathway|regulation of endoplasmic reticulum-associated protein degradation pathway|regulation of endoplasmic reticulum-associated degradation							bf	2015-06-09T14:44:27Z					biological_process											owl:Class	
GO:1902017	biolink:NamedThing	regulation of cilium assembly	Any process that modulates the frequency, rate or extent of cilium assembly.	tmpzr1t_l9r_go_relaxed.owl	regulation of cilium biogenesis|regulation of ciliogenesis							dph	2013-03-26T18:10:51Z					biological_process											owl:Class	
GO:0140435	biolink:NamedThing	negative regulation of protein localization to meiotic spindle pole body	Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to a meiotic spindle pole body.	tmpzr1t_l9r_go_relaxed.owl								pg	2020-02-24T13:27:15Z					biological_process											owl:Class	
GO:0140433	biolink:NamedThing	regulation of protein localization to meiotic spindle pole body	Any process that modulates the frequency, rate or extent of protein localization to a meiotic spindle pole body.	tmpzr1t_l9r_go_relaxed.owl								pg	2020-02-24T13:26:53Z					biological_process											owl:Class	
GO:0043354	biolink:NamedThing	enucleate erythrocyte maturation	A developmental process, independent of morphogenetic (shape) change, that is required for an enucleate erythrocyte to attain its fully functional state. An enucleate erythrocyte is an erythrocyte without a nucleus.	tmpzr1t_l9r_go_relaxed.owl	enucleate RBC maturation|enucleate red blood cell maturation													biological_process											owl:Class	
GO:0042635	biolink:NamedThing	positive regulation of hair cycle	Any process that activates or increases the frequency, rate or extent of the cyclical phases of growth (anagen), regression (catagen), quiescence (telogen), and shedding (exogen) in the life of a hair.	tmpzr1t_l9r_go_relaxed.owl	activation of hair cycle|up-regulation of hair cycle|stimulation of hair cycle|upregulation of hair cycle|up regulation of hair cycle													biological_process											owl:Class	
GO:0110159	biolink:NamedThing	regulation of mitotic spindle formation (spindle phase one)	Any process that modulates the frequency, rate or extent of the cell cycle process in which the distance is lengthened between poles of the mitotic spindle during mitotic prophase (spindle phase one).	tmpzr1t_l9r_go_relaxed.owl								kmv	2019-08-12T15:10:26Z					biological_process											owl:Class	
GO:1901193	biolink:NamedThing	regulation of formation of translation preinitiation complex	Any process that modulates the frequency, rate or extent of formation of translation preinitiation complex.	tmpzr1t_l9r_go_relaxed.owl	regulation of formation of translation pre-initiation complex|regulation of translation preinitiation complex assembly							ss	2012-07-25T02:31:20Z					biological_process											owl:Class	
GO:1904688	biolink:NamedThing	regulation of cytoplasmic translational initiation	Any process that modulates the frequency, rate or extent of cytoplasmic translational initiation.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/21560						dos	2015-09-25T14:39:38Z					biological_process											owl:Class	
GO:0034966	biolink:NamedThing	intronic box H/ACA snoRNA processing	Any process involved in the conversion of a primary box H/ACA type small nucleolar RNA (snoRNA) transcript that resides within, and is processed from, the intron of a pre-mRNA into a mature box H/ACA snoRNA.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0031070	biolink:NamedThing	intronic snoRNA processing	The biogenesis of a snoRNA molecule which resides within, and is processed from, the intron of a pre-mRNA.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0051556	biolink:NamedThing	leucoanthocyanidin metabolic process	The chemical reactions and pathways involving leucoanthocyanidins, a class of colorless intermediates in the biosynthetic pathway of the pigmented flavonoids.	tmpzr1t_l9r_go_relaxed.owl	leucoanthocyanidin metabolism				MetaCyc:PWY1F-823									biological_process											owl:Class	
GO:1901152	biolink:NamedThing	vistamycin biosynthetic process	The chemical reactions and pathways resulting in the formation of vistamycin.	tmpzr1t_l9r_go_relaxed.owl	ribostamycin biosynthesis|ribostamycin synthesis|ribostamycin biosynthetic process|ribostamycin anabolism|vistamycin synthesis|vistamycin anabolism|vistamycin biosynthesis|ribostamycin formation|vistamycin formation							yaf	2012-07-17T04:27:15Z					biological_process											owl:Class	
GO:0016170	biolink:NamedThing	interleukin-15 receptor binding	Binding to an interleukin-15 receptor.	tmpzr1t_l9r_go_relaxed.owl	interleukin-15 receptor ligand|IL-15													molecular_function											owl:Class	
GO:0047887	biolink:NamedThing	farnesyl diphosphate kinase activity	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate + ATP = 2-trans,6-trans-farnesyl triphosphate + ADP.	tmpzr1t_l9r_go_relaxed.owl	ATP:farnesyl-diphosphate phosphotransferase activity|farnesyl pyrophosphate kinase activity|farnesyl-diphosphate kinase activity				KEGG_REACTION:R02303|RHEA:21544|EC:2.7.4.18|MetaCyc:FARNESYL-DIPHOSPHATE-KINASE-RXN									molecular_function											owl:Class	
GO:1902640	biolink:NamedThing	propan-2-ol biosynthetic process	The chemical reactions and pathways resulting in the formation of propan-2-ol.	tmpzr1t_l9r_go_relaxed.owl	Isopropyl alcohol biosynthetic process|propan-2-ol formation|propan-2-ol biosynthesis|Isopropanol biosynthetic process|propan-2-ol synthesis|propan-2-ol anabolism							tt	2014-01-21T13:57:22Z					biological_process											owl:Class	
GO:0048918	biolink:NamedThing	posterior lateral line nerve development	The process whose specific outcome is the progression of the posterior lateral line nerve over time, from its formation to the mature structure. The posterior lateral line nerve innervates hair cells of the PLL and projects to an octavolateralis column in the hindbrain that consists of the medial octavolateralis nucleus (MON), the caudal octavolateralis nucleus, and the magnocellular nucleus.	tmpzr1t_l9r_go_relaxed.owl	PLLN development|caudal lateral line nerve development											GO:0021733		biological_process											owl:Class	
GO:0048892	biolink:NamedThing	lateral line nerve development	The process whose specific outcome is the progression of the lateral line nerve over time, form its formation to the mature structure. Lateral line nerves project primarily to an octavolateralis column in the hindbrain that consists of the medial octavolateralis nucleus (MON), the caudal octavolateralis nucleus, and the magnocellular nucleus.	tmpzr1t_l9r_go_relaxed.owl	nLL development													biological_process											owl:Class	
GO:0005581	biolink:NamedThing	collagen trimer	A protein complex consisting of three collagen chains assembled into a left-handed triple helix. These trimers typically assemble into higher order structures.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Collagen									cellular_component											owl:Class	
GO:0032202	biolink:NamedThing	telomere assembly	A cellular process that results in the aggregation, arrangement and bonding together of a set of components to form a telomere at a non-telomeric double-stranded DNA end. A telomere is a terminal region of a linear chromosome that includes telomeric DNA repeats and associated proteins.	tmpzr1t_l9r_go_relaxed.owl	telomere formation													biological_process											owl:Class	
GO:0060643	biolink:NamedThing	epithelial cell differentiation involved in mammary gland bud morphogenesis	The process in which a cell of the mammary placode becomes a cell of the mammary gland bud.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-05-29T07:58:13Z					biological_process											owl:Class	
GO:0045606	biolink:NamedThing	positive regulation of epidermal cell differentiation	Any process that activates or increases the frequency, rate or extent of epidermal cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	activation of epidermal cell differentiation|positive regulation of hypodermal cell differentiation|stimulation of epidermal cell differentiation|upregulation of epidermal cell differentiation|up-regulation of epidermal cell differentiation|up regulation of epidermal cell differentiation													biological_process											owl:Class	
GO:0043728	biolink:NamedThing	2-keto-4-methylthiobutyrate aminotransferase activity	Catalysis of the reaction: 2-keto-4-methylthiobutyrate + L-glutamine = 2-oxoglutaramate + L-methionine.	tmpzr1t_l9r_go_relaxed.owl					EC:4.1.1.-									molecular_function											owl:Class	
GO:0070226	biolink:NamedThing	sulfur:ferric ion oxidoreductase activity	Catalysis of the reaction: a perthiol + 4 Fe3+ + 3 H2O = sulfite + a thiol + 4 Fe2+ + 8 H+.	tmpzr1t_l9r_go_relaxed.owl	hydrogen sulfide:ferric ion oxidoreductase				MetaCyc:SULFFEOXIDO-RXN									molecular_function											owl:Class	
GO:1901324	biolink:NamedThing	response to trichodermin	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a trichodermin stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2012-08-30T10:11:07Z					biological_process											owl:Class	
GO:1904470	biolink:NamedThing	regulation of endothelin production	Any process that modulates the frequency, rate or extent of endothelin production.	tmpzr1t_l9r_go_relaxed.owl	regulation of endothelin-3 secretion|regulation of endothelin-2 secretion|regulation of EDN2 secretion|regulation of EDN3 secretion|regulation of endothelin secretion|regulation of endothelin-1 secretion|regulation of EDN1 secretion							sl	2015-07-09T19:57:57Z					biological_process											owl:Class	
GO:0045738	biolink:NamedThing	negative regulation of DNA repair	Any process that stops, prevents, or reduces the frequency, rate or extent of DNA repair.	tmpzr1t_l9r_go_relaxed.owl	down regulation of DNA repair|inhibition of DNA repair|downregulation of DNA repair|down-regulation of DNA repair													biological_process											owl:Class	
GO:0044218	biolink:NamedThing	other organism cell membrane	The cell membrane of a secondary organism with which the first organism is interacting.	tmpzr1t_l9r_go_relaxed.owl	foreign membrane|other organism membrane							jl	2009-11-12T02:37:44Z			GO:0044279		cellular_component											owl:Class	
GO:0033800	biolink:NamedThing	isoflavone 7-O-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + a 7-hydroxyisoflavone = S-adenosyl-L-homocysteine + a 7-methoxyisoflavone.	tmpzr1t_l9r_go_relaxed.owl	S-adenosyl-L-methionine:hydroxyisoflavone 7-O-methyltransferase activity				EC:2.1.1.150|MetaCyc:RXN-6241|RHEA:17933									molecular_function											owl:Class	
GO:0051077	biolink:NamedThing	secondary cell septum	Cell wall structures composed of linear polysaccharides which are deposited at both sides of the primary septum at 90 degrees to the primary septum.	tmpzr1t_l9r_go_relaxed.owl	secondary septum													cellular_component											owl:Class	
GO:0000935	biolink:NamedThing	division septum	A cell septum which forms as part of the division site and functions in the compartmentalization of a cell into two daughter cells at division. A division septum spans a cell and does not allow exchange of organelles or cytoplasm between compartments.	tmpzr1t_l9r_go_relaxed.owl	divison septum|cell septum surface|septum surface|complete septum	https://github.com/geneontology/go-ontology/issues/19434										GO:0043187		cellular_component											owl:Class	
GO:1904739	biolink:NamedThing	regulation of synapse organization by posttranscriptional regulation of gene expression	A posttranscriptional regulation of gene expression that results in regulation of synapse organization.	tmpzr1t_l9r_go_relaxed.owl	regulation of synapse development by posttranscriptional regulation of gene expression|regulation of synapse organisation by posttranscriptional regulation of gene expression|regulation of synapse morphogenesis by posttranscriptional regulation of gene expression|regulation of synapse organization and biogenesis by posttranscriptional regulation of gene expression							tb	2015-10-15T21:25:46Z					biological_process											owl:Class	
GO:0034764	biolink:NamedThing	positive regulation of transmembrane transport	Any process that activates or increases the frequency, rate or extent of the directed movement of a solute from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	activation of transmembrane transport|upregulation of transmembrane transport|positive regulation of membrane transport|stimulation of transmembrane transport|up-regulation of transmembrane transport|up regulation of transmembrane transport													biological_process											owl:Class	
GO:0001216	biolink:NamedThing	DNA-binding transcription activator activity	A DNA-binding transcription factor activity that activates or increases transcription of specific gene sets.	tmpzr1t_l9r_go_relaxed.owl	bacterial-type RNA polymerase transcriptional activator activity, metal ion regulated sequence-specific DNA binding|sequence-specific DNA binding bacterial-type RNA polymerase transcription factor activity involved in positive regulation of transcription|transcriptional activator activity, bacterial-type RNA polymerase core promoter proximal region sequence-specific binding|metal ion regulated sequence-specific DNA binding bacterial-type RNA polymerase transcription factor activity involved in positive regulation of transcription|transcriptional activator activity, bacterial-type RNA polymerase proximal promoter sequence-specific DNA binding|bacterial-type RNA polymerase core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding	https://github.com/geneontology/go-ontology/issues/16534|https://github.com/geneontology/go-ontology/issues/16736				For usage guidance, see comment in GO:0003700 ; DNA-binding transcription factor activity.		krc	2011-01-26T03:09:27Z			GO:0001140|GO:0001215		molecular_function											owl:Class	
GO:0044187	biolink:NamedThing	host cell lysosome	A small lytic vacuole that has cell cycle-independent morphology and is found in most host animal cells and that contains a variety of hydrolases, most of which have their maximal activities in the pH range 5-6. The contained enzymes display latency if properly isolated. About 40 different lysosomal hydrolases are known and host cell lysosomes have a great variety of morphologies and functions.	tmpzr1t_l9r_go_relaxed.owl								jl	2009-10-15T03:26:00Z					cellular_component											owl:Class	
GO:0033655	biolink:NamedThing	host cell cytoplasm part	Any constituent part of the host cell cytoplasm, all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	cytoplasm component					Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.								cellular_component											owl:Class	
GO:0097595	biolink:NamedThing	ventral disc crossbridge	Structure horizontally linking adjacent microribbons of the ventral disc in Giardia species (trophozoite stage). The composition of crossbridges is not fully known yet.	tmpzr1t_l9r_go_relaxed.owl	crossbridge|ventral disk crossbridge					Due to the asymmetric nature of the Giardia trophozoite, this term is defined spatially as the trophozoite is viewed from the dorsal side, with the two nuclei dorsal to the ventral disc, and the ventral disc toward the anterior.		pr	2014-04-03T11:23:33Z					cellular_component											owl:Class	
GO:1905448	biolink:NamedThing	positive regulation of mitochondrial ATP synthesis coupled electron transport	Any process that activates or increases the frequency, rate or extent of mitochondrial ATP synthesis coupled electron transport.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of mitochondrial ATP synthesis coupled electron transport|up regulation of mitochondrial ATP synthesis coupled electron transport|upregulation of mitochondrial ATP synthesis coupled electron transport|activation of mitochondrial ATP synthesis coupled electron transport							dph	2016-09-15T18:58:14Z					biological_process											owl:Class	
GO:1904707	biolink:NamedThing	positive regulation of vascular associated smooth muscle cell proliferation	Any process that activates or increases the frequency, rate or extent of vascular smooth muscle cell proliferation.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of VSMC proliferation|up regulation of vascular smooth muscle cell proliferation|up-regulation of vascular smooth muscle cell proliferation|positive regulation of VSMC proliferation|activation of vascular smooth muscle cell proliferation|positive regulation of vascular smooth muscle cell proliferation|activation of VSMC proliferation|upregulation of VSMC proliferation|upregulation of vascular smooth muscle cell proliferation|up regulation of VSMC proliferation							sl	2015-10-01T16:05:32Z					biological_process											owl:Class	
GO:1990430	biolink:NamedThing	extracellular matrix protein binding	Binding to a protein that is part of an extracellular matrix.	tmpzr1t_l9r_go_relaxed.owl								jl	2014-07-29T14:57:07Z					molecular_function											owl:Class	
GO:0043914	biolink:NamedThing	NADPH:sulfur oxidoreductase activity	Catalysis of the reaction: NADPH + H+ + sulfur = hydrogen sulfide + NADP+.	tmpzr1t_l9r_go_relaxed.owl	NADPH:sulphur oxidoreductase activity|NAD(P)H elemental sulfur oxidoreductase activity|NAD(P)H sulfur oxidoreductase activity|NAD(P)H sulphur oxidoreductase activity|NSR|coenzyme A-dependent NAD(P)H sulfur oxidoreductase activity|NAD(P)H:sulfur oxidoreductase activity|CoA-dependent NAD(P)H sulfur oxidoreductase activity				EC:1.8.1.18									molecular_function											owl:Class	
GO:0140398	biolink:NamedThing	versicolorin B desaturase activity	Catalyzes the reaction: versicolorin B + NADPH + O(2) <=> versicolorin A + NADP(+) + 2 H(2)O. Uses heme-thiolate as a co-factor. Involved in the synthesis of aflatoxins in the fungus Aspergillus parasiticus.	tmpzr1t_l9r_go_relaxed.owl					RHEA:35743|MetaCyc:RXN-9495|KEGG_REACTION:R10479			pg	2019-11-29T10:30:25Z					molecular_function											owl:Class	
GO:2000014	biolink:NamedThing	regulation of endosperm development	Any process that modulates the frequency, rate or extent of endosperm development.	tmpzr1t_l9r_go_relaxed.owl								tb	2010-08-05T11:22:21Z					biological_process											owl:Class	
GO:0140624	biolink:NamedThing	EGAD pathway	The protein catabolic pathway which selectively extracts ER-resident membrane proteins exported to the Golgi and endosomes for degradation by cytosolic proteasomes. It begins with phosphorylation of the ER-resident membrane protein, which triggers export of the protein from the ER to the Golgi and endosomes, followed by polyubiquitination by the Dsc E3 ubiquitin ligase complex and extraction of the ubiquitinated target, and ends with proteasomal degradation.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/21085						pg	2021-03-12T10:41:58Z					biological_process											owl:Class	
GO:0052903	biolink:NamedThing	N1-acetylspermine:oxygen oxidoreductase (3-acetamidopropanal-forming) activity	Catalysis of the reaction: H(2)O + N(1)-acetylspermine + O(2) = 3-acetamidopropanal + H(2)O(2) + spermidine.	tmpzr1t_l9r_go_relaxed.owl	N(1)-acetylpolyamine oxidase activity|polyamine oxidase activity|non-specific polyamine oxidase activity				KEGG_REACTION:R03899|RHEA:25800|MetaCyc:RXN-12090|MetaCyc:RXN-9940|EC:1.5.3.17|EC:1.5.3.13									molecular_function											owl:Class	
GO:0031285	biolink:NamedThing	regulation of sorocarp stalk cell differentiation	Any process that modulates the frequency, rate or extent of sorocarp stalk cell differentiation. An example of this process is found in Dictyostelium discoideum.	tmpzr1t_l9r_go_relaxed.owl	regulation of stalk cell differentiation													biological_process											owl:Class	
GO:0032098	biolink:NamedThing	regulation of appetite	Any process which modulates appetite, the desire or physical craving for food.	tmpzr1t_l9r_go_relaxed.owl	regulation of hunger													biological_process											owl:Class	
GO:1903582	biolink:NamedThing	negative regulation of basophil degranulation	Any process that stops, prevents or reduces the frequency, rate or extent of basophil degranulation.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of basophil degranulation|inhibition of basophil degranulation|down regulation of basophil degranulation|downregulation of basophil degranulation							sl	2014-10-31T17:37:33Z					biological_process											owl:Class	
GO:0001692	biolink:NamedThing	histamine metabolic process	The chemical reactions and pathways involving histamine, a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans.	tmpzr1t_l9r_go_relaxed.owl	histamine metabolism													biological_process											owl:Class	
GO:0043316	biolink:NamedThing	cytotoxic T cell degranulation	The regulated exocytosis of secretory granules containing preformed mediators such as perforin and granzymes by a cytotoxic T cell.	tmpzr1t_l9r_go_relaxed.owl	cytotoxic T cell granule exocytosis|cytotoxic T-lymphocyte granule exocytosis|cytotoxic T-cell degranulation|cytotoxic T-lymphocyte degranulation|cytotoxic T lymphocyte degranulation|cytotoxic T lymphocyte granule exocytosis|cytotoxic T-cell granule exocytosis													biological_process											owl:Class	
GO:0002286	biolink:NamedThing	T cell activation involved in immune response	The change in morphology and behavior of a mature or immature T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific, leading to the initiation or perpetuation of an immune response.	tmpzr1t_l9r_go_relaxed.owl	T-cell activation during immune response|T-lymphocyte activation during immune response|T cell activation during immune response|T lymphocyte activation during immune response													biological_process											owl:Class	
GO:0045968	biolink:NamedThing	negative regulation of juvenile hormone biosynthetic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of juvenile hormone.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of juvenile hormone formation|down regulation of juvenile hormone biosynthetic process|inhibition of juvenile hormone biosynthetic process|down-regulation of juvenile hormone biosynthetic process|negative regulation of juvenile hormone synthesis|downregulation of juvenile hormone biosynthetic process|negative regulation of juvenile hormone anabolism|negative regulation of juvenile hormone biosynthesis													biological_process											owl:Class	
GO:1902727	biolink:NamedThing	negative regulation of growth factor dependent skeletal muscle satellite cell proliferation	Any process that stops, prevents or reduces the frequency, rate or extent of satellite cell proliferation; dependent on specific growth factor activity such as fibroblast growth factors and transforming growth factor beta.	tmpzr1t_l9r_go_relaxed.owl								mr	2014-02-24T16:10:24Z					biological_process											owl:Class	
GO:0010234	biolink:NamedThing	anther wall tapetum cell fate specification	The process in which a cell becomes capable of differentiating autonomously into a tapetal cell of anthers in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.	tmpzr1t_l9r_go_relaxed.owl	tapetal cell fate specification													biological_process											owl:Class	
GO:0031397	biolink:NamedThing	negative regulation of protein ubiquitination	Any process that stops, prevents, or reduces the frequency, rate or extent of the addition of ubiquitin groups to a protein.	tmpzr1t_l9r_go_relaxed.owl	down regulation of protein ubiquitination|downregulation of protein ubiquitination|down-regulation of protein ubiquitination|inhibition of protein ubiquitination													biological_process											owl:Class	
GO:1904753	biolink:NamedThing	negative regulation of vascular associated smooth muscle cell migration	Any process that stops, prevents or reduces the frequency, rate or extent of vascular associated smooth muscle cell migration.	tmpzr1t_l9r_go_relaxed.owl	downregulation of vascular smooth muscle cell migration|down regulation of vascular associated smooth muscle cell migration|down regulation of vascular smooth muscle cell migration|downregulation of vascular associated smooth muscle cell migration|inhibition of vascular smooth muscle cell migration|inhibition of vascular associated smooth muscle cell migration|down-regulation of vascular smooth muscle cell migration|down-regulation of vascular associated smooth muscle cell migration|negative regulation of vascular smooth muscle cell migration							rph	2015-10-19T15:49:58Z					biological_process											owl:Class	
GO:0090648	biolink:NamedThing	response to environmental enrichment	Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the provision of a combination of complex inanimate and social stimulations in the organism's housing environment.	tmpzr1t_l9r_go_relaxed.owl	response to the introduction of novel objects							tb	2015-07-01T10:20:37Z					biological_process											owl:Class	
GO:1905312	biolink:NamedThing	positive regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis	Any process that activates or increases the frequency, rate or extent of cardiac neural crest cell migration involved in outflow tract morphogenesis.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis|upregulation of cardiac neural crest cell migration involved in outflow tract morphogenesis|up regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis|activation of cardiac neural crest cell migration involved in outflow tract morphogenesis							rl	2016-07-11T17:34:43Z					biological_process											owl:Class	
GO:1901736	biolink:NamedThing	(R)-mevalonic acid catabolic process	The chemical reactions and pathways resulting in the breakdown of (R)-mevalonic acid.	tmpzr1t_l9r_go_relaxed.owl	(R)-mevalonic acid degradation|(R)-mevalonic acid breakdown|(R)-mevalonate degradation|(R)-mevalonic acid catabolism|(R)-mevalonate breakdown|(R)-mevalonate catabolism							yaf	2013-01-11T11:25:55Z					biological_process											owl:Class	
GO:2000115	biolink:NamedThing	regulation of maintenance of bipolar cell polarity regulating cell shape	Any process that modulates the frequency, rate or extent of maintenance of bipolar cell polarity regulating in cell shape.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-09-21T06:33:26Z					biological_process											owl:Class	
GO:0051444	biolink:NamedThing	negative regulation of ubiquitin-protein transferase activity	Any process that stops, prevents, or reduces the frequency, rate or extent of ubiquitin transferase activity.	tmpzr1t_l9r_go_relaxed.owl	anaphase promoting complex inhibition|SCF complex inhibitor|down regulation of ubiquitin transferase activity|anaphase-promoting complex inhibition|ubiquitin transferase inhibitor|negative regulation of ubiquitin transferase activity|down-regulation of ubiquitin transferase activity|anaphase-promoting complex inhibitor|APC inhibitor|downregulation of ubiquitin transferase activity|anaphase promoting complex inhibitor|inhibition of ubiquitin transferase activity|APC inhibition													biological_process											owl:Class	
GO:1901424	biolink:NamedThing	response to toluene	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a toluene stimulus.	tmpzr1t_l9r_go_relaxed.owl								tt	2012-10-01T18:38:32Z					biological_process											owl:Class	
GO:0021684	biolink:NamedThing	cerebellar granular layer formation	The process that gives rise to the cerebellar granule layer. This process pertains to the initial formation of a structure from unspecified parts. The granular layer is the innermost layer of the cerebellar cortex. This layer contains densely packed small neurons, mostly granule cells. Some Golgi cells are found at the outer border. Granule neurons send parallel fibers to the upper molecular layer, where they synapse with Purkinje cell dendrites. Mossy fibers from the pontine nuclei in the white matter synapse with granule cell axons, Golgi cell axons and unipolar brush interneuron axons at cerebellar glomeruli in the granule cell layer.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0120002	biolink:NamedThing	fusiform vesicle	A cytoplasmic vesicle which contains two urothelial plaques and can deliver these plaques to the apical plasma membrane of urothelial superficial (umbrella) cells. It can also be formed by endocytosis of apical plasma membrane during contractions of the urinary bladder.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/12996						krc	2017-02-23T21:12:27Z					cellular_component											owl:Class	
GO:0071001	biolink:NamedThing	U4/U6 snRNP	A ribonucleoprotein complex that contains the extensively base paired small nuclear RNAs U4 and U6, a heptameric ring of Sm proteins associated with U4, the Lsm2-8 heptameric ring complex associated with U6, as well as several proteins that are unique to the U4 snRNP or U6 snRNPs, some of which remain associated with the U4/U6 snRNA both while the U4 snRNP is free or assembled into a series of spliceosomal complexes.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-07-30T12:00:35Z					cellular_component											owl:Class	
GO:0043805	biolink:NamedThing	indolepyruvate ferredoxin oxidoreductase activity	Catalysis of the reaction: (indol-3-yl)pyruvate + CoA + oxidized ferredoxin = S-2-(indol-3-yl)acetyl-CoA + CO2 + reduced ferredoxin.	tmpzr1t_l9r_go_relaxed.owl	indolepyruvate oxidoreductase activity|IOR|3-(indol-3-yl)pyruvate:ferredoxin oxidoreductase (decarboxylating, CoA-indole-acetylating)|3-(indol-3-yl)pyruvate synthase (ferredoxin) activity				RHEA:12645|MetaCyc:1.2.7.8-RXN|EC:1.2.7.8									molecular_function											owl:Class	
GO:0016625	biolink:NamedThing	oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which an aldehyde or ketone (oxo) group acts as a hydrogen or electron donor and reduces an iron-sulfur protein.	tmpzr1t_l9r_go_relaxed.owl	oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulphur protein as acceptor				EC:1.2.7.-									molecular_function											owl:Class	
GO:0016094	biolink:NamedThing	polyprenol biosynthetic process	The chemical reactions and pathways resulting in the formation of polyprenols, prenols with more than 4 isoprenoid residues, which may be all-trans, or a mixture of cis and trans.	tmpzr1t_l9r_go_relaxed.owl	polyprenol synthesis|polyprenol formation|polyprenol biosynthesis|polyprenol anabolism													biological_process											owl:Class	
GO:1900648	biolink:NamedThing	positive regulation of chanoclavine-I aldehyde biosynthetic process	Any process that activates or increases the frequency, rate or extent of chanoclavine-I aldehyde biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of chanoclavine-I aldehyde anabolism|positive regulation of chanoclavine-I aldehyde synthesis|up-regulation of chanoclavine-I aldehyde biosynthetic process|upregulation of chanoclavine-I aldehyde biosynthetic process|positive regulation of chanoclavine-I aldehyde anabolism|activation of chanoclavine-I aldehyde synthesis|positive regulation of chanoclavine-I aldehyde biosynthesis|up regulation of chanoclavine-I aldehyde synthesis|up regulation of chanoclavine-I aldehyde formation|up-regulation of chanoclavine-I aldehyde formation|activation of chanoclavine-I aldehyde formation|activation of chanoclavine-I aldehyde biosynthesis|upregulation of chanoclavine-I aldehyde formation|upregulation of chanoclavine-I aldehyde synthesis|upregulation of chanoclavine-I aldehyde biosynthesis|up-regulation of chanoclavine-I aldehyde biosynthesis|up regulation of chanoclavine-I aldehyde biosynthesis|up regulation of chanoclavine-I aldehyde anabolism|activation of chanoclavine-I aldehyde anabolism|positive regulation of chanoclavine-I aldehyde formation|up-regulation of chanoclavine-I aldehyde synthesis|activation of chanoclavine-I aldehyde biosynthetic process|up regulation of chanoclavine-I aldehyde biosynthetic process|upregulation of chanoclavine-I aldehyde anabolism							di	2012-05-22T04:05:06Z					biological_process											owl:Class	
GO:2000991	biolink:NamedThing	regulation of galactomannan catabolic process	Any process that modulates the frequency, rate or extent of galactomannan catabolic process.	tmpzr1t_l9r_go_relaxed.owl								tt	2011-08-08T03:15:53Z					biological_process											owl:Class	
GO:0070837	biolink:NamedThing	dehydroascorbic acid transport	The directed movement of dehydroascorbate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Dehydroascorbate, 5-(1,2-dihydroxyethyl)furan-2,3,4(5H)-trione, is an oxidized form of vitamin C.	tmpzr1t_l9r_go_relaxed.owl	dehydroascorbate transport							mah	2009-07-30T05:24:31Z					biological_process											owl:Class	
GO:0051180	biolink:NamedThing	vitamin transport	The directed movement of vitamins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A vitamin is one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body.	tmpzr1t_l9r_go_relaxed.owl	vitamin or cofactor transport													biological_process											owl:Class	
GO:0010628	biolink:NamedThing	positive regulation of gene expression	Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0044623	biolink:NamedThing	positive regulation of cell migration in other organism	Any process that activates or increases the frequency, rate or extent of cell migration in a second organism.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-07-04T04:44:59Z					biological_process											owl:Class	
GO:0044621	biolink:NamedThing	modulation of cell migration in other organism	The process in which an organism effects a change in the process of cell migration in a second organism.	tmpzr1t_l9r_go_relaxed.owl	regulation of cell migration in other organism							jl	2012-07-04T04:40:13Z					biological_process											owl:Class	
GO:0061096	biolink:NamedThing	negative regulation of turning behavior involved in mating	Any process that decreases the rate, frequency or extent of turning behavior involved in mating. Turning behavior is the sharp ventral turn performed by the male as he approaches either the hermaphrodite head or tail, whilst trying to locate his partner's vulva. Turning occurs via a sharp ventral coil of the male's tail.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-04-26T02:12:24Z					biological_process											owl:Class	
GO:1905788	biolink:NamedThing	negative regulation of detection of mechanical stimulus involved in sensory perception of touch	Any process that stops, prevents or reduces the frequency, rate or extent of detection of mechanical stimulus involved in sensory perception of touch.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of perception of touch, detection of mechanical stimulus|negative regulation of tactition, sensory detection of mechanical stimulus|down regulation of sensory transduction of mechanical stimulus during perception of touch|downregulation of perception of touch, detection of mechanical stimulus|down regulation of detection of mechanical stimulus involved in sensory perception of touch|down-regulation of sensory transduction of mechanical stimulus during perception of touch|down-regulation of detection of mechanical stimulus involved in sensory perception of touch|inhibition of tactition, sensory detection of mechanical stimulus|down-regulation of perception of touch, detection of mechanical stimulus|inhibition of detection of mechanical stimulus involved in sensory perception of touch|down-regulation of sensory detection of mechanical stimulus during perception of touch|down-regulation of tactition, sensory detection of mechanical stimulus|downregulation of detection of mechanical stimulus involved in sensory perception of touch|negative regulation of perception of touch, sensory transduction of mechanical stimulus|inhibition of perception of touch, sensory detection of mechanical stimulus|downregulation of sensory transduction of mechanical stimulus during perception of touch|negative regulation of sensory detection of mechanical stimulus during perception of touch|inhibition of perception of touch, sensory transduction of mechanical stimulus|down regulation of tactition, sensory detection of mechanical stimulus|downregulation of perception of touch, sensory transduction of mechanical stimulus|negative regulation of perception of touch, sensory detection of mechanical stimulus|inhibition of sensory detection of mechanical stimulus during perception of touch|down regulation of sensory detection of mechanical stimulus during perception of touch|down regulation of perception of touch, sensory transduction of mechanical stimulus|downregulation of tactition, sensory detection of mechanical stimulus|down regulation of perception of touch, sensory detection of mechanical stimulus|down-regulation of perception of touch, sensory transduction of mechanical stimulus|down-regulation of perception of touch, sensory detection of mechanical stimulus|down regulation of perception of touch, detection of mechanical stimulus|downregulation of perception of touch, sensory detection of mechanical stimulus|negative regulation of sensory transduction of mechanical stimulus during perception of touch|inhibition of sensory transduction of mechanical stimulus during perception of touch|downregulation of sensory detection of mechanical stimulus during perception of touch|inhibition of perception of touch, detection of mechanical stimulus							hbye	2017-01-09T15:11:14Z					biological_process											owl:Class	
GO:0031645	biolink:NamedThing	negative regulation of nervous system process	Any process that stops, prevents, or reduces the frequency, rate or extent of a neurophysiological process.	tmpzr1t_l9r_go_relaxed.owl	down regulation of neurological process|negative regulation of neurological process|downregulation of neurological process|negative regulation of neurophysiological process|negative regulation of neurological system process|inhibition of neurological process|down-regulation of neurological process													biological_process											owl:Class	
GO:1905828	biolink:NamedThing	regulation of prostaglandin catabolic process	Any process that modulates the frequency, rate or extent of prostaglandin catabolic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of prostaglandin breakdown|regulation of prostaglandin catabolism|regulation of prostaglandin degradation							sl	2017-01-16T21:36:39Z					biological_process											owl:Class	
GO:1903641	biolink:NamedThing	positive regulation of gastrin-induced gastric acid secretion	Any process that activates or increases the frequency, rate or extent of gastrin-induced gastric acid secretion.	tmpzr1t_l9r_go_relaxed.owl	up regulation of gastrin-induced gastric acid secretion|activation of gastrin-induced gastric acid secretion|up-regulation of gastrin-induced gastric acid secretion|upregulation of gastrin-induced gastric acid secretion							sl	2014-11-20T20:54:37Z					biological_process											owl:Class	
GO:0060454	biolink:NamedThing	positive regulation of gastric acid secretion	Any process that increases the rate frequency or extent of gastric secretion. Gastric secretion is the regulated release of gastric acid (hydrochloric acid) by parietal or oxyntic cells during digestion.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0032102	biolink:NamedThing	negative regulation of response to external stimulus	Any process that stops, prevents, or reduces the frequency, rate or extent of a response to an external stimulus.	tmpzr1t_l9r_go_relaxed.owl	inhibition of response to external stimulus|down-regulation of response to external stimulus|down regulation of response to external stimulus|downregulation of response to external stimulus					Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.								biological_process											owl:Class	
GO:0009860	biolink:NamedThing	pollen tube growth	Growth of pollen via tip extension of the intine wall.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0018051	biolink:NamedThing	C-terminal peptidyl-tryptophan amidation	The formation of a C-terminal peptidyl-tryptophan amide by hydrolysis and oxidation of an interior Trp-Gly peptide in a secreted protein.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0098									biological_process											owl:Class	
GO:0018211	biolink:NamedThing	peptidyl-tryptophan modification	The chemical alteration of a tryptophan residue in a peptide.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0060409	biolink:NamedThing	positive regulation of acetylcholine metabolic process	Any process that increases the rate, frequency or extent of the chemical reactions and pathways involving acetylcholine, the acetic acid ester of the organic base choline. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0046723	biolink:NamedThing	malic acid secretion	The controlled release of malic acid, hydroxybutanedioic (hydroxysuccinic) acid, by a cell or a tissue.	tmpzr1t_l9r_go_relaxed.owl	malate secretion|hydroxysuccinic acid secretion													biological_process											owl:Class	
GO:0046717	biolink:NamedThing	acid secretion	The controlled release of acid by a cell or a tissue.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0031552	biolink:NamedThing	negative regulation of brain-derived neurotrophic factor-activated receptor activity	Any process that stops, prevents, or reduces the frequency, rate or extent of brain-derived neurotrophic factor-activated receptor activity.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of BDNF receptor activity|downregulation of brain-derived neurotrophic factor receptor activity|down regulation of brain-derived neurotrophic factor receptor activity|negative regulation of brain-derived neurotrophic factor receptor activity|down-regulation of brain-derived neurotrophic factor receptor activity|inhibition of brain-derived neurotrophic factor receptor activity													biological_process											owl:Class	
GO:0071988	biolink:NamedThing	protein localization to spindle pole body	A process in which a protein is transported to, or maintained at, the spindle pole body.	tmpzr1t_l9r_go_relaxed.owl	protein localisation to spindle pole body							mah	2010-10-25T10:56:33Z					biological_process											owl:Class	
GO:0140444	biolink:NamedThing	cytoskeleton-nuclear membrane anchor activity	The binding activity of a molecule that brings together a cytoskeletal protein or protein complex and a nuclear membrane lipid or membrane-associated protein, in order to maintain the localization of the cytoskeleton at a specific location of the nuclear membrane.	tmpzr1t_l9r_go_relaxed.owl	nuclear membrane-cytoskeleton anchor activity|cytoskeletal protein-nuclear membrane anchor activity|cytoskeleton nuclear membrane anchor activity|cytoskeletal protein-nuclear membrane adaptor activity	https://github.com/geneontology/go-ontology/issues/18283						pg	2020-03-24T14:57:59Z					molecular_function											owl:Class	
GO:0050668	biolink:NamedThing	positive regulation of homocysteine metabolic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving homocysteine.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of homocysteine metabolism|positive regulation of Hcy metabolic process|activation of homocysteine metabolic process|upregulation of homocysteine metabolic process|stimulation of homocysteine metabolic process|up regulation of homocysteine metabolic process|up-regulation of homocysteine metabolic process|positive regulation of Hcy metabolism													biological_process											owl:Class	
GO:1903064	biolink:NamedThing	positive regulation of reverse cholesterol transport	Any process that activates or increases the frequency, rate or extent of reverse cholesterol transport.	tmpzr1t_l9r_go_relaxed.owl	up regulation of reverse cholesterol transport|up-regulation of reverse cholesterol transport|activation of reverse cholesterol transport|upregulation of reverse cholesterol transport							rl	2014-05-28T15:15:40Z					biological_process											owl:Class	
GO:0090606	biolink:NamedThing	single-species surface biofilm formation	A process in which microorganisms produce an extracellular matrix and form multicellular aggregates at an air-liquid interface.	tmpzr1t_l9r_go_relaxed.owl	multicellular pellicle formation							tb	2014-09-16T14:47:11Z			GO:0032022		biological_process											owl:Class	
GO:0090604	biolink:NamedThing	surface biofilm formation	A process in which planktonically growing microorganisms grow at the surface of a liquid-air interface and produce extracellular polymers that facilitate matrix formation, resulting in a change in the organisms' growth rate and gene transcription.	tmpzr1t_l9r_go_relaxed.owl								tb	2014-09-16T14:38:45Z					biological_process											owl:Class	
GO:0002321	biolink:NamedThing	natural killer cell progenitor differentiation	The process in which a precursor cell type acquires the specialized features of a natural killer cell progenitor.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0002320	biolink:NamedThing	lymphoid progenitor cell differentiation	The process in which a precursor cell type acquires the specialized features of a lymphoid progenitor cell. Lymphoid progenitor cells include progenitor cells for any of the lymphoid lineages.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0038161	biolink:NamedThing	prolactin signaling pathway	A series of molecular signals initiated by the binding of the peptide hormone prolactin to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.	tmpzr1t_l9r_go_relaxed.owl	prolactin-mediated signaling pathway|PRL signaling pathway							bf	2012-05-14T01:52:59Z					biological_process											owl:Class	
GO:0019394	biolink:NamedThing	glucarate catabolic process	The chemical reactions and pathways resulting in the breakdown of glucarate, the anion of glucaric acid.	tmpzr1t_l9r_go_relaxed.owl	glucarate degradation|glucarate catabolism|glucarate breakdown				MetaCyc:GLUCARDEG-PWY									biological_process											owl:Class	
GO:0032586	biolink:NamedThing	protein storage vacuole membrane	The lipid bilayer surrounding a protein storage vacuole.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0009705	biolink:NamedThing	plant-type vacuole membrane	The lipid bilayer surrounding a vacuole that retains the same shape regardless of cell cycle phase. The membrane separates its contents from the cytoplasm of the cell. An example of this component is found in Arabidopsis thaliana.	tmpzr1t_l9r_go_relaxed.owl	tonoplast|membrane of vacuole with cell cycle-independent morphology|vacuolar membrane													cellular_component											owl:Class	
GO:0042069	biolink:NamedThing	regulation of catecholamine metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving catecholamines.	tmpzr1t_l9r_go_relaxed.owl	regulation of catecholamine metabolism													biological_process											owl:Class	
GO:0030893	biolink:NamedThing	meiotic cohesin complex	A cohesin complex that mediates sister chromatid cohesion during meiosis; has a subunit composition distinct from that of the mitotic cohesin complex.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0008278	biolink:NamedThing	cohesin complex	A protein complex that is required for sister chromatid cohesion in eukaryotes. The cohesin complex forms a molecular ring complex, and is composed of structural maintenance of chromosomes (SMC) and kleisin proteins. For example, in yeast, the complex is composed of the SMC proteins Smc1p and Smc3p, and the kleisin protein Scc1p. In vertebrates, the complex is composed of the SMC1 (SMC1A or SMC1B) and SMC3 heterodimer attached via their hinge domains to a kleisin (RAD21, REC8 or RAD21L) which links them, and one STAG protein (STAG1, STAG2 or STAG3).	tmpzr1t_l9r_go_relaxed.owl	9S cohesin|cohesin core heterodimer|SMC complex|14S cohesin|Smc1-Smc3 complex|SMC/kleisin ring complex											GO:0008280|GO:0008279|GO:0043222		cellular_component											owl:Class	
GO:0052639	biolink:NamedThing	salicylic acid glucosyltransferase (ester-forming) activity	Catalysis of the reaction: salicylic acid + UDP-glucose = salicylic acid glucose ester + UDP.	tmpzr1t_l9r_go_relaxed.owl	UDP:glucose:salicylate glucosyltransferase (ester-forming) activity|UDP:glucose:2-hydroxybenzoic acid glucosyltransferase (ester-forming) activity|salicylic acid glucosyltransferase activity|UDP:glucose:SA glucosyltransferase (ester-forming) activity|UDP:glucose:salicylic acid glucosyltransferase (ester-forming) activity				RHEA:62316|MetaCyc:RXN-11659									molecular_function											owl:Class	
GO:2000443	biolink:NamedThing	regulation of toll-like receptor 21 signaling pathway	Any process that modulates the frequency, rate or extent of toll-like receptor 21 signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	regulation of toll-like receptor 21 signalling pathway|regulation of TLR21 signaling pathway							bf	2011-03-04T10:31:48Z					biological_process											owl:Class	
GO:0080111	biolink:NamedThing	DNA demethylation	The removal of a methyl group from one or more nucleotides within an DNA molecule.	tmpzr1t_l9r_go_relaxed.owl								dhl	2009-04-27T02:42:05Z					biological_process											owl:Class	
GO:0070988	biolink:NamedThing	demethylation	The process of removing one or more methyl groups from a molecule.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-10-29T03:12:51Z					biological_process											owl:Class	
GO:1904175	biolink:NamedThing	positive regulation of histone demethylase activity (H3-K4 specific)	Any process that activates or increases the frequency, rate or extent of histone demethylase activity (H3-K4 specific).	tmpzr1t_l9r_go_relaxed.owl	upregulation of histone demethylase activity (H3-K4 specific)|activation of histone demethylase activity (H3-K4 specific)|up-regulation of histone demethylase activity (H3-K4 specific)|up regulation of histone demethylase activity (H3-K4 specific)							dph	2015-04-24T19:29:45Z					biological_process											owl:Class	
GO:0031058	biolink:NamedThing	positive regulation of histone modification	Any process that activates or increases the frequency, rate or extent of the covalent alteration of a histone.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of histone modification|upregulation of histone modification|up regulation of histone modification|stimulation of histone modification|activation of histone modification													biological_process											owl:Class	
GO:0018639	biolink:NamedThing	xylene monooxygenase activity	Catalysis of the reactions: toluene + 1/2 O2 = benzyl alcohol, and xylene + 1/2 O2 = methylbenzyl alcohol.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_enzymeID:e0172|EC:1.14.13.-									molecular_function											owl:Class	
GO:0103089	biolink:NamedThing	methylthiohexylmalate isomerase activity	Catalysis of the reaction: 2-(6'-methylthio)hexylmalate <=> 3-(6'-methylthio)hexylmalate.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXNQT-4173									molecular_function											owl:Class	
GO:0050486	biolink:NamedThing	intramolecular transferase activity, transferring hydroxy groups	Catalysis of the transfer of a hydroxyl group from one position to another within a single molecule.	tmpzr1t_l9r_go_relaxed.owl					EC:5.4.4.-									molecular_function											owl:Class	
GO:0043634	biolink:NamedThing	polyadenylation-dependent ncRNA catabolic process	The chemical reactions and pathways resulting in the breakdown of a noncoding RNA (ncRNA) molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target ncRNA.	tmpzr1t_l9r_go_relaxed.owl	poly(A)-dependent ncRNA catabolic process													biological_process											owl:Class	
GO:2001031	biolink:NamedThing	positive regulation of cellular glucuronidation	Any process that activates or increases the frequency, rate or extent of cellular glucuronidation.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of cellular glucuronide biosynthesis|positive regulation of cellular glucuronoside biosynthesis|positive regulation of cellular glucuronide biosynthetic process|positive regulation of cellular glucuronoside biosynthetic process							rl	2011-08-22T01:10:59Z					biological_process											owl:Class	
GO:0072595	biolink:NamedThing	maintenance of protein localization in organelle	Any process in which a protein is maintained in a specific location a specific location on or in an organelle, and is prevented from moving elsewhere. Encompasses establishment of localization in the membrane or lumen of a membrane-bounded organelle.	tmpzr1t_l9r_go_relaxed.owl	maintenance of protein localisation to organelle|maintenance of protein localization to organelle							mah	2011-02-14T02:09:13Z					biological_process											owl:Class	
GO:2000771	biolink:NamedThing	positive regulation of establishment or maintenance of cell polarity regulating cell shape	Any process that activates or increases the frequency, rate or extent of establishment or maintenance of cell polarity regulating cell shape.	tmpzr1t_l9r_go_relaxed.owl								mah	2011-06-22T01:56:55Z					biological_process											owl:Class	
GO:2000293	biolink:NamedThing	negative regulation of defecation	Any process that stops, prevents or reduces the frequency, rate or extent of defecation.	tmpzr1t_l9r_go_relaxed.owl								bf	2010-12-21T09:23:13Z					biological_process											owl:Class	
GO:0042931	biolink:NamedThing	enterobactin transmembrane transporter activity	Enables the directed movement of the siderochrome enterochelin, a cyclic trimer of 2, 3 dihydroxybenzoylserine from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	enterochelin transporter activity|enterobactin transporter activity													molecular_function											owl:Class	
GO:0040014	biolink:NamedThing	regulation of multicellular organism growth	Any process that modulates the frequency, rate or extent of growth of the body of an organism so that it reaches its usual body size.	tmpzr1t_l9r_go_relaxed.owl	regulation of body growth|regulation of body size													biological_process											owl:Class	
GO:2001008	biolink:NamedThing	positive regulation of cellulose biosynthetic process	Any process that activates or increases the frequency, rate or extent of cellulose biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of cellulose anabolism|positive regulation of cellulose formation|positive regulation of cellulose biosynthesis|positive regulation of cellulose synthesis							tt	2011-08-08T08:42:29Z					biological_process											owl:Class	
GO:1905270	biolink:NamedThing	Meynert cell differentiation	The process in which a relatively unspecialized cell acquires the specialized features of a Meynert cell.	tmpzr1t_l9r_go_relaxed.owl								cjm	2016-06-15T23:44:17Z					biological_process											owl:Class	
GO:1900222	biolink:NamedThing	negative regulation of amyloid-beta clearance	Any process that stops, prevents or reduces the frequency, rate or extent of amyloid-beta clearance.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of beta-amyloid clearance|down regulation of beta-amyloid clearance|down-regulation of beta-amyloid clearance|inhibition of beta-amyloid clearance|downregulation of beta-amyloid clearance							vk	2012-03-22T01:29:41Z					biological_process											owl:Class	
GO:1900221	biolink:NamedThing	regulation of amyloid-beta clearance	Any process that modulates the frequency, rate or extent of amyloid-beta clearance.	tmpzr1t_l9r_go_relaxed.owl	regulation of beta-amyloid clearance							vk	2012-03-22T01:29:32Z					biological_process											owl:Class	
GO:0102792	biolink:NamedThing	sinapaldehyde:NAD(P)+ oxidoreductase activity	Catalysis of the reaction: sinapoyl aldehyde + NADP + H2O <=> 2 H+ + trans-sinapate + NADPH.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-8014									molecular_function											owl:Class	
GO:0047170	biolink:NamedThing	glucarate O-hydroxycinnamoyltransferase activity	Catalysis of the reaction: D-glucarate + sinapoyl-CoA = 2-O-sinapoyl-D-glucarate + CoA.	tmpzr1t_l9r_go_relaxed.owl	sinapoyl-CoA:glucarate O-(hydroxycinnamoyl)transferase activity				KEGG_REACTION:R02899|MetaCyc:2.3.1.131-RXN|EC:2.3.1.131|RHEA:23308									molecular_function											owl:Class	
GO:1903095	biolink:NamedThing	ribonuclease III complex	A protein complex which is capable of ribonuclease III activity.	tmpzr1t_l9r_go_relaxed.owl						An example of this is RNC in human (Q9NRR4) in PMID:22393237 (inferred from direct assay).		bhm	2014-06-03T15:06:39Z					cellular_component											owl:Class	
GO:1902555	biolink:NamedThing	endoribonuclease complex	A protein complex which is capable of endoribonuclease activity.	tmpzr1t_l9r_go_relaxed.owl	Ire1 complex homodimer|Ire1 complex homooligomer|Ire1 complex dimer					An example is IRE1 in S. cerevisiae (UniProt ID P32361) in PMID:18191223 (inferred from direct assay).		bhm	2013-12-06T16:09:31Z					cellular_component											owl:Class	
GO:0102649	biolink:NamedThing	acetoacetyl-ACP synthase activity	Catalysis of the reaction: acetyl-CoA + malonyl-CoA + H+ + a holo-[acyl-carrier protein] <=> acetoacetyl-ACP + 2 coenzyme A + carbon dioxide.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-15810									molecular_function											owl:Class	
GO:0010389	biolink:NamedThing	regulation of G2/M transition of mitotic cell cycle	Any signalling pathway that modulates the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to M phase of the mitotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl	regulation of mitotic entry													biological_process											owl:Class	
GO:0061780	biolink:NamedThing	mitotic cohesin loading	The protein localization to chromatin by which a cohesin ring complex is topologically linked to DNA as part of the mitotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl								dph	2016-08-23T13:00:34Z					biological_process											owl:Class	
GO:0104004	biolink:NamedThing	cellular response to environmental stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an environmental stimulus.	tmpzr1t_l9r_go_relaxed.owl								dos	2017-02-17T16:02:42Z					biological_process											owl:Class	
GO:1901815	biolink:NamedThing	astaxanthin biosynthetic process	The chemical reactions and pathways resulting in the formation of astaxanthin.	tmpzr1t_l9r_go_relaxed.owl	astaxanthin biosynthesis|astaxanthin formation|astaxanthin synthesis|astaxanthin anabolism							yaf	2013-01-22T10:37:11Z					biological_process											owl:Class	
GO:0016123	biolink:NamedThing	xanthophyll biosynthetic process	The chemical reactions and pathways resulting in the formation of xanthophylls, oxygen-containing carotenoids.	tmpzr1t_l9r_go_relaxed.owl	xanthophyll synthesis|xanthophyll biosynthesis|xanthophyll anabolism|xanthophyll formation													biological_process											owl:Class	
GO:0019267	biolink:NamedThing	asparagine biosynthetic process from cysteine	The chemical reactions and pathways resulting in the formation of asparagine from other compounds, including cysteine.	tmpzr1t_l9r_go_relaxed.owl	asparagine synthesis from cysteine|asparagine formation from cysteine|asparagine anabolism from cysteine				MetaCyc:ASPSYNII-PWY									biological_process											owl:Class	
GO:0035642	biolink:NamedThing	histone methyltransferase activity (H3-R17 specific)	Catalysis of the reaction: S-adenosyl-L-methionine + (histone H3)-arginine (position 17) = S-adenosyl-L-homocysteine + (histone H3)-N-methyl-arginine (position 17). This reaction is the addition of a methyl group to arginine at position 17 of histone H3.	tmpzr1t_l9r_go_relaxed.owl	histone-arginine N-methyltransferase activity (H3-R17 specific)|histone methylase activity (H3-R17 specific)							bf	2011-01-19T10:41:43Z					molecular_function											owl:Class	
GO:0008469	biolink:NamedThing	histone-arginine N-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + (histone)-arginine = S-adenosyl-L-homocysteine + (histone)-N-methyl-arginine.	tmpzr1t_l9r_go_relaxed.owl	protein methylase I activity|histone protein methylase activity|histone-arginine N-methylase activity|histone protein methylase I|S-adenosyl-L-methionine:histone-arginine nomega-methyltransferase activity|nuclear protein (histone) N-methyltransferase activity|histone methyltransferase activity|S-adenosyl-L-methionine:histone-arginine omega-N-methyltransferase activity				Reactome:R-HSA-8936584|Reactome:R-HSA-5661117|Reactome:R-HSA-8937113|Reactome:R-HSA-5205799|Reactome:R-HSA-8936608|Reactome:R-HSA-8937022|Reactome:R-HSA-5205861|Reactome:R-HSA-5216234							GO:0016276		molecular_function											owl:Class	
GO:0140494	biolink:NamedThing	migrasome	A vesicular organelle that forms on retraction fibers behind migrating cells and mediates the release of cytoplasmic contents during cell migration.	tmpzr1t_l9r_go_relaxed.owl								pg	2020-07-10T15:09:40Z					cellular_component											owl:Class	
GO:0046697	biolink:NamedThing	decidualization	The cellular and vascular changes occurring in the endometrium of the pregnant uterus just after the onset of blastocyst implantation. This process involves the proliferation and differentiation of the fibroblast-like endometrial stromal cells into large, polyploid decidual cells that eventually form the maternal component of the placenta.	tmpzr1t_l9r_go_relaxed.owl	decidual cell reaction				Wikipedia:Decidualization									biological_process											owl:Class	
GO:0034841	biolink:NamedThing	mentha-1,3-dione-CoA ligase activity	Catalysis of the reaction: mentha-1,3-dione + CoASH = 3,7-dimethyl-5-oxo-octyl-CoA.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r1186									molecular_function											owl:Class	
GO:0110005	biolink:NamedThing	positive regulation of tRNA C5-cytosine methylation	Any process that activates or increases the frequency, rate or extent of tRNA C5-cytosine methylation.	tmpzr1t_l9r_go_relaxed.owl								kmv						biological_process											owl:Class	
GO:0110004	biolink:NamedThing	positive regulation of tRNA methylation	Any process that activates or increases the frequency, rate or extent of tRNA methylation.	tmpzr1t_l9r_go_relaxed.owl								kmv						biological_process											owl:Class	
GO:0019376	biolink:NamedThing	galactolipid catabolic process	The chemical reactions and pathways resulting in the breakdown of galactolipids, any glycolipid containing one of more residues of galactose and/or N-acetylgalactosamine.	tmpzr1t_l9r_go_relaxed.owl	galactolipid degradation|galactolipid breakdown|galactolipid catabolism													biological_process											owl:Class	
GO:0019374	biolink:NamedThing	galactolipid metabolic process	The chemical reactions and pathways involving galactolipids, any glycolipid containing one of more residues of galactose and/or N-acetylgalactosamine.	tmpzr1t_l9r_go_relaxed.owl	galactolipid metabolism													biological_process											owl:Class	
GO:0051892	biolink:NamedThing	negative regulation of cardioblast differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of cardioblast differentiation, the process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of cardioblast differentiation|inhibition of cardioblast differentiation|downregulation of cardioblast differentiation|down regulation of cardioblast differentiation													biological_process											owl:Class	
GO:0016323	biolink:NamedThing	basolateral plasma membrane	The region of the plasma membrane that includes the basal end and sides of the cell. Often used in reference to animal polarized epithelial membranes, where the basal membrane is the part attached to the extracellular matrix, or in plant cells, where the basal membrane is defined with respect to the zygotic axis.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0000429	biolink:NamedThing	carbon catabolite regulation of transcription from RNA polymerase II promoter	A transcription regulation process in which the presence of one carbon source leads to the modulation of the frequency, rate, or extent of transcription, from an RNA polymerase II promoter, of specific genes involved in the metabolism of other carbon sources.	tmpzr1t_l9r_go_relaxed.owl	regulation of transcription from RNA polymerase II promoter by carbon catabolites													biological_process											owl:Class	
GO:1900502	biolink:NamedThing	positive regulation of butyryl-CoA catabolic process to butyrate	Any process that activates or increases the frequency, rate or extent of butyryl-CoA catabolic process to butyrate.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of butyryl-CoA catabolism to butyrate|up regulation of butyryl-CoA catabolism to butyrate|up regulation of butyryl-CoA catabolic process to butyrate|positive regulation of butyryl-CoA catabolism to butyrate|activation of butyryl-CoA catabolism to butyrate|activation of butyryl-CoA catabolic process to butyrate|up-regulation of butyryl-CoA catabolic process to butyrate|upregulation of butyryl-CoA catabolic process to butyrate|upregulation of butyryl-CoA catabolism to butyrate							tt	2012-05-02T03:56:40Z					biological_process											owl:Class	
GO:0052714	biolink:NamedThing	mannosyl-inositol phosphorylceramide phospholipase activity	Catalysis of the reaction: mannosyl-inositol phosphorylceramide + H2O = C26-phytoceramide + mannosylphosphorylinositol.	tmpzr1t_l9r_go_relaxed.owl								ai	2011-08-05T08:02:57Z					molecular_function											owl:Class	
GO:0052713	biolink:NamedThing	inositol phosphorylceramide phospholipase activity	Catalysis of the reaction: inositol phosphorylceramide + H2O = C26-phytoceramide + phosphorylinositol.	tmpzr1t_l9r_go_relaxed.owl								ai	2011-08-05T04:51:03Z					molecular_function											owl:Class	
GO:0030642	biolink:NamedThing	cellular sulfate ion homeostasis	Any process involved in the maintenance of an internal steady state of sulfate ions at the level of a cell.	tmpzr1t_l9r_go_relaxed.owl	sulphate ion homeostasis													biological_process											owl:Class	
GO:0055063	biolink:NamedThing	sulfate ion homeostasis	Any process involved in the maintenance of an internal steady state of sulfate ions within an organism or cell.	tmpzr1t_l9r_go_relaxed.owl	sulphate ion homeostasis|sulfate homeostasis											GO:0080174		biological_process											owl:Class	
GO:1900114	biolink:NamedThing	positive regulation of histone H3-K9 trimethylation	Any process that activates or increases the frequency, rate or extent of histone H3-K9 trimethylation.	tmpzr1t_l9r_go_relaxed.owl	upregulation of histone H3-K9 trimethylation|up-regulation of histone H3-K9 trimethylation|up regulation of histone H3-K9 trimethylation|activation of histone H3-K9 trimethylation							bf	2012-02-21T09:09:58Z					biological_process											owl:Class	
GO:1905303	biolink:NamedThing	positive regulation of macropinocytosis	Any process that activates or increases the frequency, rate or extent of macropinocytosis.	tmpzr1t_l9r_go_relaxed.owl	activation of macropinocytosis|upregulation of macropinocytosis|up-regulation of macropinocytosis|up regulation of macropinocytosis							pad	2016-07-04T14:16:49Z					biological_process											owl:Class	
GO:0008623	biolink:NamedThing	CHRAC	An ISWI complex that contains an ATPase subunit of the ISWI family (SNF2H in mammals, Isw2 in S. cerevisiae), an ACF1 homolog, and additional small histone fold subunits (generally two of these, but Xenopus has only one and some additional non-conserved subunits). CHRAC plays roles in the regulation of RNA polymerase II transcription and in DNA replication and repair.	tmpzr1t_l9r_go_relaxed.owl	ISW2 complex|chromatin accessibility complex											GO:0016588		cellular_component											owl:Class	
GO:0031010	biolink:NamedThing	ISWI-type complex	Any nuclear protein complex that contains an ATPase subunit of the imitation switch (ISWI) family. ISWI ATPases are involved in assembling chromatin and in sliding and spacing nucleosomes to regulate transcription of nuclear RNA polymerases I, II, and III and also DNA replication, recombination and repair.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0042894	biolink:NamedThing	fosmidomycin transport	The directed movement of fosmidomycin, a phosphonic acid derivative with potent activity against Gram-negative organisms, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0051153	biolink:NamedThing	regulation of striated muscle cell differentiation	Any process that modulates the frequency, rate or extent of striated muscle cell differentiation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0030272	biolink:NamedThing	5-formyltetrahydrofolate cyclo-ligase activity	Catalysis of the reaction: 5-formyltetrahydrofolate + ATP = 5,10-methenyltetrahydrofolate + ADP + H(+) + phosphate.	tmpzr1t_l9r_go_relaxed.owl	methenyl-THF synthetase activity|5-formyltetrahydrofolate cyclo-ligase (ADP-forming)|5,10-methenyltetrahydrofolate synthetase activity|5-Formyltetrahydrofolate cyclodehydrase activity|5-formyltetrahydrofolate cyclodehydrase|formyltetrahydrofolic cyclodehydrase activity				EC:6.3.3.2|MetaCyc:5-FORMYL-THF-CYCLO-LIGASE-RXN|Reactome:R-HSA-6801342|KEGG_REACTION:R02301|RHEA:10488							GO:0019006		molecular_function											owl:Class	
GO:0016882	biolink:NamedThing	cyclo-ligase activity	Catalysis of the joining of two groups within a single molecule via a carbon-nitrogen bond, forming heterocyclic ring, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.	tmpzr1t_l9r_go_relaxed.owl					EC:6.3.3.-									molecular_function											owl:Class	
GO:0005746	biolink:NamedThing	mitochondrial respirasome	The protein complexes that form the mitochondrial electron transport system (the respiratory chain), associated with the inner mitochondrial membrane. The respiratory chain complexes transfer electrons from an electron donor to an electron acceptor and are associated with a proton pump to create a transmembrane electrochemical gradient.	tmpzr1t_l9r_go_relaxed.owl	mitochondrial respiratory chain|mitochondrial respiratory chain supercomplex|mitochondrial electron transport chain|mitochondrial respiratory supercomplex	https://github.com/geneontology/go-ontology/issues/12846						pr	2012-02-23T05:13:54Z			GO:0097249		cellular_component											owl:Class	
GO:0070469	biolink:NamedThing	respirasome	The protein complexes that form the electron transport system (the respiratory chain), associated with a cell membrane, usually the plasma membrane (in prokaryotes) or the inner mitochondrial membrane (on eukaryotes). The respiratory chain complexes transfer electrons from an electron donor to an electron acceptor and are associated with a proton pump to create a transmembrane electrochemical gradient.	tmpzr1t_l9r_go_relaxed.owl	membrane electron transport chain|respiratory chain	https://github.com/geneontology/go-ontology/issues/12846												cellular_component											owl:Class	
GO:0021594	biolink:NamedThing	rhombomere formation	The process that gives rise to the rhombomere. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0070443	biolink:NamedThing	Mad-Max complex	A transcriptional repressor complex that consists of a heterodimer of the bHLH-ZIP proteins Mad and Max.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0080092	biolink:NamedThing	regulation of pollen tube growth	Any process that modulates the frequency, rate or extent of pollen tube growth.	tmpzr1t_l9r_go_relaxed.owl								dhl	2009-04-22T04:41:29Z					biological_process											owl:Class	
GO:0097478	biolink:NamedThing	leaflet of membrane bilayer	Any of the two layers of lipid molecules that constitute a membrane.	tmpzr1t_l9r_go_relaxed.owl	membrane leaflet							pr	2013-05-07T14:24:37Z					cellular_component											owl:Class	
GO:0060408	biolink:NamedThing	regulation of acetylcholine metabolic process	Any process that modulates the rate, frequency or extent of the chemical reactions and pathways involving acetylcholine, the acetic acid ester of the organic base choline. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0033238	biolink:NamedThing	regulation of cellular amine metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform amines.	tmpzr1t_l9r_go_relaxed.owl	regulation of amine metabolism													biological_process											owl:Class	
GO:1904661	biolink:NamedThing	negative regulation of sensory perception of bitter taste	Any process that stops, prevents or reduces the frequency, rate or extent of sensory perception of bitter taste.	tmpzr1t_l9r_go_relaxed.owl	downregulation of bitter taste perception|downregulation of sensory perception of bitter taste|inhibition of sensory perception of bitter taste|down-regulation of sensory perception of bitter taste|down regulation of bitter taste perception|negative regulation of bitter taste perception|down-regulation of bitter taste perception|down regulation of sensory perception of bitter taste|inhibition of bitter taste perception							mr	2015-09-04T17:54:17Z					biological_process											owl:Class	
GO:1904660	biolink:NamedThing	regulation of sensory perception of bitter taste	Any process that modulates the frequency, rate or extent of sensory perception of bitter taste.	tmpzr1t_l9r_go_relaxed.owl	regulation of bitter taste perception							mr	2015-09-04T17:54:10Z					biological_process											owl:Class	
GO:0090657	biolink:NamedThing	telomeric loop disassembly	The telomere maintenance process in which telomeric loops are disassembled to permit efficient telomere replication.	tmpzr1t_l9r_go_relaxed.owl	t-loop disassembly|T loop disassembly							tb	2015-07-07T13:53:40Z					biological_process											owl:Class	
GO:1902513	biolink:NamedThing	regulation of organelle transport along microtubule	Any process that modulates the frequency, rate or extent of organelle transport along microtubule.	tmpzr1t_l9r_go_relaxed.owl	regulation of microtubule-based organelle localization							dph	2013-11-15T20:15:17Z					biological_process											owl:Class	
GO:0017128	biolink:NamedThing	phospholipid scramblase activity	Catalysis of the movement of phospholipids from one membrane bilayer leaflet to the other, by an ATP-independent mechanism.	tmpzr1t_l9r_go_relaxed.owl						Nomenclature note. Scramblases are ATP-independent, non-selective, translocases inducing non-specific transbilayer movements across the membrane. Flippases and floppases are ATP-dependent transbilayer lipid translocators. According to an extensively used, though not universal, nomenclature, they catalyze lipid transfer towards the inward monolayer (flippases) or towards the outward monolayer (floppases).								molecular_function											owl:Class	
GO:0005548	biolink:NamedThing	phospholipid transporter activity	Enables the directed movement of phospholipids into, out of or within a cell, or between cells. Phospholipids are a class of lipids containing phosphoric acid as a mono- or diester.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-216757|Reactome:R-HSA-8857662|Reactome:R-HSA-382553|Reactome:R-HSA-8867876|Reactome:R-HSA-5678749|Reactome:R-HSA-5678706|Reactome:R-HSA-8865637							GO:0008497		molecular_function											owl:Class	
GO:1900962	biolink:NamedThing	regulation of methanophenazine biosynthetic process	Any process that modulates the frequency, rate or extent of methanophenazine biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of methanophenazine formation|regulation of methanophenazine anabolism|regulation of methanophenazine synthesis|regulation of methanophenazine biosynthesis							tt	2012-06-14T03:53:15Z					biological_process											owl:Class	
GO:0048789	biolink:NamedThing	cytoskeletal matrix organization at active zone	The assembly and arrangement of cytomatrix proteins to form complexes in the cell cortex beneath the active zone, i.e. just beneath the presynaptic plasma membrane.	tmpzr1t_l9r_go_relaxed.owl	cytoskeletal matrix organisation at active zone													biological_process											owl:Class	
GO:0030562	biolink:NamedThing	rRNA 2'-O-ribose methylation guide activity	Specifies the site of 2'-O-ribose methylation in an rRNA molecule by base pairing with a short sequence around the target residue.	tmpzr1t_l9r_go_relaxed.owl						Note that this term describes the activity of a nucleic acid, usually RNA, gene product that interacts with other RNA molecules via base pairing; it should not be used to annotate proteins.								molecular_function											owl:Class	
GO:0030556	biolink:NamedThing	rRNA modification guide activity	Specifies the site of a posttranscriptional modification in an rRNA molecule by base pairing with a short sequence around the target residue.	tmpzr1t_l9r_go_relaxed.owl						Note that this term describes the activity of a nucleic acid, usually RNA, gene product that interacts with other RNA molecules via base pairing; it should not be used to annotate proteins.								molecular_function											owl:Class	
GO:0007320	biolink:NamedThing	insemination	The introduction of semen or sperm into the genital tract of a female.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Insemination									biological_process											owl:Class	
GO:1902956	biolink:NamedThing	regulation of mitochondrial electron transport, NADH to ubiquinone	Any process that modulates the frequency, rate or extent of mitochondrial electron transport, NADH to ubiquinone.	tmpzr1t_l9r_go_relaxed.owl	regulation of complex I (NADH to ubiquinone)|regulation of oxidative phosphorylation, NADH to ubiquinone							dph	2014-05-02T15:30:12Z					biological_process											owl:Class	
GO:0075525	biolink:NamedThing	viral translational termination-reinitiation	A process which occurs as part of viral mRNA translation which allows expression of a downstream open reading frame (ORF) in a dicistronic mRNA. In this process, ribosomes translate the upstream ORF but following termination, a proportion of 40S subunits remain tethered to the mRNA and go on to re-initiate translation at the start codon of the downstream ORF.	tmpzr1t_l9r_go_relaxed.owl	viral translation involving termination-reinitiation|termination reinitiation involved in viral translation|viral translation involving translational stop-start|viral translation involving termination re-initiation				VZ:858	This term is intended to annotate gene products involved in the process of viral translational termination-reinitiation, not viral proteins produced by this translation process.		jl	2011-08-04T12:01:22Z					biological_process											owl:Class	
GO:0045346	biolink:NamedThing	regulation of MHC class II biosynthetic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of MHC class II.	tmpzr1t_l9r_go_relaxed.owl	regulation of major histocompatibility complex class II biosynthesis|regulation of MHC class II biosynthesis|regulation of MHC class II formation|regulation of MHC class II synthesis|regulation of major histocompatibility complex class II biosynthetic process|regulation of MHC class II anabolism													biological_process											owl:Class	
GO:0034218	biolink:NamedThing	ascospore wall chitin metabolic process	The chemical reactions and pathways involving ascospore wall chitin, a linear polysaccharide consisting of P-1,4-linked N-acetyl-D-glucosamine residues, found in the walls of ascospores.	tmpzr1t_l9r_go_relaxed.owl	ascospore wall chitin metabolism													biological_process											owl:Class	
GO:0070496	biolink:NamedThing	positive regulation of thrombin-activated receptor signaling pathway	Any process that activates or increases the frequency, rate or extent of thrombin-activated receptor protein signaling pathway activity. A thrombin receptor signaling pathway is the series of molecular signals generated as a consequence of a thrombin-activated receptor binding to one of its physiological ligands.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of thrombin receptor signaling pathway|positive regulation of thrombin receptor signalling pathway													biological_process											owl:Class	
GO:0061362	biolink:NamedThing	negative regulation of maintenance of bipolar cell polarity regulating cell shape	Any process that decreases the frequency, rate or extent of maintenance of bipolar cell polarity regulating cell shape.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-10-13T09:03:42Z					biological_process											owl:Class	
GO:2000750	biolink:NamedThing	negative regulation of establishment or maintenance of bipolar cell polarity regulating cell shape	Any process that stops, prevents or reduces the frequency, rate or extent of establishment or maintenance of bipolar cell polarity regulating cell shape.	tmpzr1t_l9r_go_relaxed.owl								mah	2011-06-16T11:51:49Z					biological_process											owl:Class	
GO:0022880	biolink:NamedThing	protein-N(PI)-phosphohistidine-N-acetylglucosamine phosphotransferase system transporter activity	Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + N-acetylglucosamine(out) = protein histidine + N-acetylglucosamine phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.	tmpzr1t_l9r_go_relaxed.owl	N-acetylglucosamine PTS transporter activity													molecular_function											owl:Class	
GO:0015572	biolink:NamedThing	N-acetylglucosamine transmembrane transporter activity	Enables the transfer of N-acetylglucosamine from one side of a membrane to the other. The D isomer of N-acetylglucosamine is a common structural unit of glycoproteins in plants, bacteria and animals; it is often the terminal sugar of an oligosaccharide group of a glycoprotein.	tmpzr1t_l9r_go_relaxed.owl	N-acetylchitosamine transmembrane transporter activity|D-GlcNAc transmembrane transporter activity|N-Acetyl-D-glucosamine permease|N-acetylglucosamine permease activity|N-acetyl-D-glucosamine transmembrane transporter activity											GO:0015580		molecular_function											owl:Class	
GO:0048787	biolink:NamedThing	presynaptic active zone membrane	The membrane portion of the presynaptic active zone; it is the site where docking and fusion of synaptic vesicles occurs for the release of neurotransmitters.	tmpzr1t_l9r_go_relaxed.owl	active zone presynaptic plasma membrane|active zone plasma membrane|pre-synaptic active zone membrane|active zone pre-synaptic plasma membrane				NIF_Subcellular:sao2038461087									cellular_component											owl:Class	
GO:0001161	biolink:NamedThing	intronic transcription regulatory region sequence-specific DNA binding	Binding to an intronic DNA sequence that regulates the transcription of the transcript it is contained within.	tmpzr1t_l9r_go_relaxed.owl	intronic transcription regulatory region DNA binding	https://github.com/geneontology/go-ontology/issues/19312				To minimize ambiguity in the use of the word "promoter" in GO, we have chosen the phrase "transcription regulatory region" to refer to all of the regulatory regions. Regulatory regions in the DNA which control initiation may include the "core promoter" where the basal transcription machinery binds, the "core promoter proximal region" where regulatory factors other than the basal machinery bind. There are also additional regulatory regions, in both the DNA and the RNA transcript, which regulate elongation or termination of transcription.		krc	2011-01-28T03:44:02Z			GO:0044213		molecular_function											owl:Class	
GO:0003136	biolink:NamedThing	negative regulation of heart induction by canonical Wnt signaling pathway	Any canonical Wnt signaling that decreases the rate, frequency or extent of heart induction.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of heart induction by canonical Wnt receptor signalling pathway|negative regulation of cardioblast cell fate specification by Wnt receptor signaling pathway|negative regulation of heart induction by canonical Wnt-activated signaling pathway|negative regulation of heart induction by canonical Wnt receptor signaling pathway							tb	2009-09-22T03:26:17Z					biological_process											owl:Class	
GO:0100012	biolink:NamedThing	regulation of heart induction by canonical Wnt signaling pathway	Any canonical Wnt signaling pathway process that regulates heart induction.	tmpzr1t_l9r_go_relaxed.owl								cjm	2015-04-02T04:13:19Z					biological_process											owl:Class	
GO:0061387	biolink:NamedThing	regulation of extent of cell growth	Any process that modulates the extent of cell growth.	tmpzr1t_l9r_go_relaxed.owl								dph	2011-07-14T10:15:42Z					biological_process											owl:Class	
GO:0090331	biolink:NamedThing	negative regulation of platelet aggregation	Any process that decreases the rate, frequency or extent of platelet aggregation. Platelet aggregation is the adhesion of one platelet to one or more other platelets via adhesion molecules.	tmpzr1t_l9r_go_relaxed.owl	platelet disaggregation							tb	2010-05-14T10:46:08Z					biological_process											owl:Class	
GO:0048024	biolink:NamedThing	regulation of mRNA splicing, via spliceosome	Any process that modulates the frequency, rate or extent of mRNA splicing via a spliceosomal mechanism.	tmpzr1t_l9r_go_relaxed.owl	regulation of pre-mRNA splicing|regulation of nuclear mRNA splicing via U2-type spliceosome|regulation of nuclear mRNA splicing, via spliceosome											GO:0035055		biological_process											owl:Class	
GO:0047212	biolink:NamedThing	2-coumarate O-beta-glucosyltransferase activity	Catalysis of the reaction: trans-2-coumarate + UDP-D-glucose = trans-beta-D-glucosyl-2-hydroxycinnamate + H(+) + UDP.	tmpzr1t_l9r_go_relaxed.owl	UDP-glucose:trans-2-hydroxycinnamate O-beta-D-glucosyltransferase activity|UDPG:o-coumaric acid O-glucosyltransferase activity|UDPglucose:trans-2-hydroxycinnamate O-beta-D-glucosyltransferase activity|uridine diphosphoglucose-o-coumarate glucosyltransferase activity				KEGG_REACTION:R03710|MetaCyc:2.4.1.114-RXN|RHEA:10236|EC:2.4.1.114									molecular_function											owl:Class	
GO:0002266	biolink:NamedThing	follicular dendritic cell activation	A change in the morphology or behavior of a follicular dendritic cell resulting from exposure to an activating factor such as a cellular or soluble ligand.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0032752	biolink:NamedThing	positive regulation of interleukin-3 production	Any process that activates or increases the frequency, rate, or extent of interleukin-3 production.	tmpzr1t_l9r_go_relaxed.owl	stimulation of interleukin-3 production|activation of interleukin-3 production|up regulation of interleukin-3 production|upregulation of interleukin-3 production|positive regulation of IL-3 production|up-regulation of interleukin-3 production|positive regulation of interleukin-3 biosynthetic process											GO:0045401		biological_process											owl:Class	
GO:0039016	biolink:NamedThing	cell-cell signaling involved in pronephros development	Any process that mediates the transfer of information from one cell to another and contributes to the progression of the pronephros over time, from its formation to the mature organ.	tmpzr1t_l9r_go_relaxed.owl	cell-cell signalling involved in pronephros development|cell-cell signaling involved in pronephric kidney development							bf	2010-07-02T10:03:16Z					biological_process											owl:Class	
GO:0052697	biolink:NamedThing	xenobiotic glucuronidation	The modification of a xenobiotic substance by the conjugation of glucuronic acid. The resultant glucuronosides are often much more water-soluble than the xenobiotic precursor, enabling efficient excretion.	tmpzr1t_l9r_go_relaxed.owl	phase II metabolism							ai	2011-07-27T05:37:50Z					biological_process											owl:Class	
GO:0075221	biolink:NamedThing	negative regulation of zoospore encystment on host	Any process that stops, prevents, or reduces the frequency, rate or extent of zoospore encystment on host. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0043987	biolink:NamedThing	histone H3-S10 phosphorylation	The modification of histone H3 by the addition of an phosphate group to a serine residue at position 10 of the histone.	tmpzr1t_l9r_go_relaxed.owl	histone H3 phosphorylation at S10|histone H3S10 phosphorylation											GO:0043986		biological_process											owl:Class	
GO:1990158	biolink:NamedThing	DnaB-DnaC-DnaT-PriA-PriB complex	A protein-DNA complex consisting of the helicase loading complex DnaB-DnaC, replication restart proteins DnaT, PriA and PriB, and associated DNA. Involved in the restart of DNA replication after a stalled replication fork has been repaired.	tmpzr1t_l9r_go_relaxed.owl	DnaB-DnaC-DnaT-PriA-PriB preprimosome|phi-X174-type preprimosome							bhm	2013-08-02T11:52:55Z					cellular_component											owl:Class	
GO:0003254	biolink:NamedThing	regulation of membrane depolarization	Any process that modulates the rate, frequency or extent of membrane depolarization. Membrane depolarization is the process in which membrane potential changes in the depolarizing direction from the resting potential, usually from negative to positive.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-10-14T10:54:09Z					biological_process											owl:Class	
GO:0006227	biolink:NamedThing	dUDP biosynthetic process	The chemical reactions and pathways resulting in the formation of dUDP, deoxyuridine diphosphate (2'-deoxy-5'-uridylyl phosphate).	tmpzr1t_l9r_go_relaxed.owl	dUDP biosynthesis|dUDP synthesis|dUDP anabolism|dUDP formation													biological_process											owl:Class	
GO:0010988	biolink:NamedThing	regulation of low-density lipoprotein particle clearance	Any process that modulates the rate, frequency or extent of low-density lipoprotein particle clearance. Low-density lipoprotein particle clearance is the process in which a low-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-06-01T12:13:07Z					biological_process											owl:Class	
GO:0051410	biolink:NamedThing	detoxification of nitrogen compound	Any process that reduces or removes the toxicity of nitrogenous compounds which are dangerous or toxic. This includes the aerobic conversion of toxic compounds to harmless substances.	tmpzr1t_l9r_go_relaxed.owl	nitric oxide (NO) detoxification|detoxification of nitrogenous compound													biological_process											owl:Class	
GO:0060889	biolink:NamedThing	limb basal epidermal cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a limb epidermal basal cell. A epidermal basal cell cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into more specialized cell of the limb epidermis.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-08-13T01:22:12Z					biological_process											owl:Class	
GO:1990714	biolink:NamedThing	hydroxyproline O-galactosyltransferase activity	Catalysis of the transfer of galactose from UDP-galactose to hydroxyproline residues present in the peptide backbone.	tmpzr1t_l9r_go_relaxed.owl	HPGT							tb	2015-03-26T23:22:09Z					molecular_function											owl:Class	
GO:0008378	biolink:NamedThing	galactosyltransferase activity	Catalysis of the transfer of a galactosyl group to an acceptor molecule, typically another carbohydrate or a lipid.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-1964501									molecular_function											owl:Class	
GO:0021949	biolink:NamedThing	brainstem precerebellar neuron precursor migration	The early migration of a precerebellar neuronal precursor in which a cell move from the rhombic lip, orthogonal to the direction of radial migration and ultimately reside in the brainstem.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0021934	biolink:NamedThing	hindbrain tangential cell migration	The migration of a cell in the hindbrain in which cells move orthogonal to the direction of radial migration.	tmpzr1t_l9r_go_relaxed.owl	hindbrain neurophilic migration													biological_process											owl:Class	
GO:1905725	biolink:NamedThing	protein localization to microtubule end	A process in which a protein is transported to, or maintained in, a location at a microtubule end.	tmpzr1t_l9r_go_relaxed.owl	protein localisation to microtubule end							mah	2016-11-28T15:01:43Z					biological_process											owl:Class	
GO:0035372	biolink:NamedThing	protein localization to microtubule	A process in which a protein is transported to, or maintained at, a microtubule.	tmpzr1t_l9r_go_relaxed.owl	protein localisation to microtubule							bf	2010-03-11T11:00:56Z					biological_process											owl:Class	
GO:0018907	biolink:NamedThing	dimethyl sulfoxide metabolic process	The chemical reactions and pathways involving dimethyl sulfoxide, DMSO (C2H6OS), an alkyl sulfoxide that is practically odorless in its purified form. As a highly polar organic liquid, it is a powerful solvent. Its biological activities include the ability to penetrate plant and animal tissues and to preserve living cells during freezing.	tmpzr1t_l9r_go_relaxed.owl	dimethyl sulfoxide metabolism|DMSO metabolism|DMSO metabolic process|dimethyl sulphoxide metabolic process|dimethyl sulphoxide metabolism				UM-BBD_pathwayID:sulf									biological_process											owl:Class	
GO:1904410	biolink:NamedThing	negative regulation of secretory granule organization	Any process that stops, prevents or reduces the frequency, rate or extent of secretory granule organization.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of secretory granule organisation|down regulation of secretory granule organization and biogenesis|downregulation of secretory granule organization and biogenesis|downregulation of secretory granule organization|down-regulation of secretory granule organization and biogenesis|down regulation of secretory granule organisation|down-regulation of secretory granule organization|downregulation of secretory granule organisation|inhibition of secretory granule organisation|negative regulation of secretory granule organisation|inhibition of secretory granule organization and biogenesis|inhibition of secretory granule organization|down regulation of secretory granule organization|negative regulation of secretory granule organization and biogenesis							sl	2015-06-25T19:40:49Z					biological_process											owl:Class	
GO:0018441	biolink:NamedThing	iron incorporation into iron-sulfur cluster via hexakis-L-cysteinyl L-serinyl octairon heptasulfide	The incorporation of iron into a 8Fe-7S iron-sulfur cluster via hexakis-L-cysteinyl L-serinyl octairon heptasulfide, found in nitrogenase.	tmpzr1t_l9r_go_relaxed.owl	iron incorporation into iron-sulphur cluster via hexakis-L-cysteinyl L-serinyl octairon heptasulphide				RESID:AA0300									biological_process											owl:Class	
GO:0035449	biolink:NamedThing	extrinsic component of plastid thylakoid membrane	The component of a plastid thylakoid membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.	tmpzr1t_l9r_go_relaxed.owl	peripheral to plastid thylakoid membrane|extrinsic to plastid thylakoid membrane							bf	2010-04-16T10:14:24Z					cellular_component											owl:Class	
GO:0070658	biolink:NamedThing	neuromast hair cell differentiation involved in neuromast regeneration	Differentiation of new neuromast sensory hair cells to replace those lost or destroyed by injury.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-05-28T04:16:27Z					biological_process											owl:Class	
GO:0048886	biolink:NamedThing	neuromast hair cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a neuromast hair cell. Hair cells are the sensory receptors of the neuromast and are located in a portion of the neuromast called the sensory strip. Each hair cell of the neuromast is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. There are approximately seven hair cells within each neuromast, with each hair cell innervated by afferent and efferent neurons.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0007503	biolink:NamedThing	fat body development	The process whose specific outcome is the progression of the fat body over time, from its formation to the mature structure. A fat body is an insect gland dorsal to the insect gut, with a function analogous to that of the vertebrate liver. It is a storage organ for fats, glycogen and protein and is a major site of intermediary metabolism.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0010745	biolink:NamedThing	negative regulation of macrophage derived foam cell differentiation	Any process that decreases the rate, frequency or extent of macrophage derived foam cell differentiation. Macrophage derived foam cell differentiation is the process in which a macrophage acquires the specialized features of a foam cell. A foam cell is a type of cell containing lipids in small vacuoles and typically seen in atherosclerotic lesions, as well as other conditions.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0042401	biolink:NamedThing	cellular biogenic amine biosynthetic process	The chemical reactions and pathways occurring at the level of individual cells resulting in the formation of any of a group of naturally occurring, biologically active amines, such as norepinephrine, histamine, and serotonin, many of which act as neurotransmitters.	tmpzr1t_l9r_go_relaxed.owl	biogenic amine formation|biogenic amine synthesis|biogenic amine biosynthesis|biogenic amine anabolism													biological_process											owl:Class	
GO:0070836	biolink:NamedThing	caveola assembly	The aggregation, arrangement and bonding together of a set of components to form a caveola. A caveola is a plasma membrane raft that forms a small pit, depression, or invagination that communicates with the outside of a cell and extends inward, indenting the cytoplasm and the cell membrane.	tmpzr1t_l9r_go_relaxed.owl	caveolar biogenesis|caveola formation							mah	2009-07-30T04:45:54Z					biological_process											owl:Class	
GO:0044854	biolink:NamedThing	plasma membrane raft assembly	The aggregation, arrangement and bonding together of a set of components to form a plasma membrane raft.	tmpzr1t_l9r_go_relaxed.owl								jl	2014-07-23T15:58:16Z					biological_process											owl:Class	
GO:1903452	biolink:NamedThing	positive regulation of G1 to G0 transition	Any process that activates or increases the frequency, rate or extent of G1 to G0 transition.	tmpzr1t_l9r_go_relaxed.owl	upregulation of stationary phase|upregulation of G1/G0 transition|up regulation of G1 to G0 transition|upregulation of G1 to G0 transition|activation of stationary phase|up regulation of cell cycle quiescence|up regulation of establishment of cell quiescence|positive regulation of G1/G0 transition|up-regulation of G1 to G0 transition|activation of establishment of cell quiescence|upregulation of establishment of cell quiescence|up-regulation of G1/G0 transition|up regulation of stationary phase|activation of cell cycle quiescence|positive regulation of cell cycle quiescence|positive regulation of establishment of cell quiescence|upregulation of cell cycle quiescence|up regulation of G1/G0 transition|activation of G1/G0 transition|positive regulation of stationary phase|activation of G1 to G0 transition|up-regulation of stationary phase|up-regulation of cell cycle quiescence|up-regulation of establishment of cell quiescence							di	2014-09-19T22:23:30Z					biological_process											owl:Class	
GO:2000060	biolink:NamedThing	positive regulation of ubiquitin-dependent protein catabolic process	Any process that activates or increases the frequency, rate or extent of ubiquitin-dependent protein catabolic process.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of protein ubiquitination during ubiquitin-dependent protein catabolism|positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process|positive regulation of protein degradation tagging activity|positive regulation of protein ubiquitinylation during ubiquitin-dependent protein catabolic process|positive regulation of protein ubiquitination during ubiquitin-dependent protein breakdown|positive regulation of protein ubiquitylation during ubiquitin-dependent protein catabolism|positive regulation of protein ubiquitinylation during ubiquitin-dependent protein catabolism|positive regulation of protein ubiquitylation during ubiquitin-dependent protein catabolic process|positive regulation of protein ubiquitination during ubiquitin-dependent protein degradation							jl	2010-08-20T01:24:03Z					biological_process											owl:Class	
GO:1903052	biolink:NamedThing	positive regulation of proteolysis involved in cellular protein catabolic process	Any process that activates or increases the frequency, rate or extent of proteolysis involved in cellular protein catabolic process.	tmpzr1t_l9r_go_relaxed.owl	up regulation of peptidolysis involved in cellular protein catabolic process|activation of proteolysis during cellular protein catabolic process|upregulation of proteolysis during cellular protein catabolism|upregulation of peptidolysis involved in cellular protein catabolism|positive regulation of peptidolysis involved in cellular protein catabolism|upregulation of proteolysis involved in cellular protein catabolic process|upregulation of peptidolysis during cellular protein catabolic process|up-regulation of peptidolysis involved in cellular protein catabolic process|activation of peptidolysis involved in cellular protein catabolic process|activation of peptidolysis during cellular protein catabolic process|positive regulation of proteolysis during cellular protein catabolic process|up regulation of peptidolysis during cellular protein catabolism|up regulation of proteolysis during cellular protein catabolic process|positive regulation of proteolysis during cellular protein catabolism|activation of peptidolysis during cellular protein catabolism|up-regulation of peptidolysis during cellular protein catabolic process|up-regulation of proteolysis involved in cellular protein catabolic process|up-regulation of proteolysis during cellular protein catabolic process|up regulation of proteolysis during cellular protein catabolism|positive regulation of peptidolysis involved in cellular protein catabolic process|up regulation of peptidolysis involved in cellular protein catabolism|activation of peptidolysis involved in cellular protein catabolism|upregulation of peptidolysis involved in cellular protein catabolic process|up-regulation of peptidolysis during cellular protein catabolism|up-regulation of proteolysis during cellular protein catabolism|up regulation of proteolysis involved in cellular protein catabolic process|activation of proteolysis during cellular protein catabolism|up-regulation of peptidolysis involved in cellular protein catabolism|upregulation of peptidolysis during cellular protein catabolism|positive regulation of peptidolysis during cellular protein catabolic process|positive regulation of peptidolysis during cellular protein catabolism|up regulation of peptidolysis during cellular protein catabolic process|upregulation of proteolysis during cellular protein catabolic process|activation of proteolysis involved in cellular protein catabolic process					overexpression of cathepsin C propeptide significantly increased the degradation of intestinal alkaline phosphatase (IAP)		rl	2014-05-22T18:00:57Z					biological_process											owl:Class	
GO:0008327	biolink:NamedThing	methyl-CpG binding	Binding to a methylated cytosine/guanine dinucleotide.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0032345	biolink:NamedThing	negative regulation of aldosterone metabolic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving aldosterone.	tmpzr1t_l9r_go_relaxed.owl	down regulation of aldosterone metabolic process|downregulation of aldosterone metabolic process|inhibition of aldosterone metabolic process|down-regulation of aldosterone metabolic process|negative regulation of aldosterone metabolism													biological_process											owl:Class	
GO:0050900	biolink:NamedThing	leukocyte migration	The movement of a leukocyte within or between different tissues and organs of the body.	tmpzr1t_l9r_go_relaxed.owl	leukocyte trafficking|immune cell trafficking|leucocyte migration|leucocyte trafficking|immune cell migration													biological_process											owl:Class	
GO:1904233	biolink:NamedThing	negative regulation of aconitate hydratase activity	Any process that stops, prevents or reduces the frequency, rate or extent of aconitate hydratase activity.	tmpzr1t_l9r_go_relaxed.owl	down regulation of citrate(isocitrate) hydro-lyase (cis-aconitate-forming)|down-regulation of citrate(isocitrate) hydro-lyase (cis-aconitate-forming)|down-regulation of aconitase activity|negative regulation of cis-aconitase activity|down-regulation of aconitate hydratase activity|downregulation of aconitase activity|downregulation of citrate(isocitrate) hydro-lyase activity|down-regulation of cis-aconitase activity|inhibition of cis-aconitase activity|down regulation of aconitate hydratase activity|downregulation of citrate(isocitrate) hydro-lyase (cis-aconitate-forming)|down regulation of cis-aconitase activity|inhibition of aconitase activity|down-regulation of citrate(isocitrate) hydro-lyase activity|inhibition of citrate(isocitrate) hydro-lyase (cis-aconitate-forming)|down regulation of aconitase activity|downregulation of cis-aconitase activity|downregulation of aconitate hydratase activity|down regulation of citrate(isocitrate) hydro-lyase activity|negative regulation of citrate(isocitrate) hydro-lyase (cis-aconitate-forming)|negative regulation of aconitase activity|inhibition of aconitate hydratase activity|negative regulation of citrate(isocitrate) hydro-lyase activity|inhibition of citrate(isocitrate) hydro-lyase activity							rl	2015-05-15T09:55:23Z					biological_process											owl:Class	
GO:0051350	biolink:NamedThing	negative regulation of lyase activity	Any process that stops or reduces the rate of lyase activity, the catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond.	tmpzr1t_l9r_go_relaxed.owl	down regulation of lyase activity|inhibition of lyase activity|lyase inhibitor|down-regulation of lyase activity|downregulation of lyase activity													biological_process											owl:Class	
GO:0019310	biolink:NamedThing	inositol catabolic process	The chemical reactions and pathways resulting in the breakdown of inositol, 1,2,3,4,5,6-cyclohexanehexol, a growth factor for animals and microorganisms.	tmpzr1t_l9r_go_relaxed.owl	inositol degradation|inositol catabolism|vitamin Bh catabolism|myo-inositol catabolism|vitamin Bh catabolic process|myo-inositol catabolic process|inositol breakdown				MetaCyc:P562-PWY									biological_process											owl:Class	
GO:1990763	biolink:NamedThing	arrestin family protein binding	Binding to a member of the arrestin family, proteins involved in agonist-mediated desensitization of G protein-coupled receptors.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-06-09T23:29:42Z					molecular_function											owl:Class	
GO:0050937	biolink:NamedThing	regulation of iridophore differentiation	Any process that modulates the frequency, rate or extent of iridophore differentiation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0015046	biolink:NamedThing	rubredoxin-NADP+ reductase activity	Catalysis of the reaction: reduced rubredoxin + NADP+ = oxidized rubredoxin + NADPH + H+.	tmpzr1t_l9r_go_relaxed.owl					RHEA:13949|EC:1.18.1.4									molecular_function											owl:Class	
GO:0015045	biolink:NamedThing	rubredoxin-NAD(P)+ reductase activity	Catalysis of the reaction: reduced rubredoxin + NAD(P)+ = oxidized rubredoxin + NAD(P)H + H+.	tmpzr1t_l9r_go_relaxed.owl	NAD(P)H--rubredoxin oxidoreductase activity|dinucleotide phosphate reductase activity|rubredoxin:NAD(P)+ oxidoreductase activity|rubredoxin--nicotinamide adenine activity|NAD(P)--rubredoxin oxidoreductase activity|rubredoxin--nicotinamide adenine dinucleotide (phosphate) reductase activity|NADPH:rubredoxin reductase activity				MetaCyc:RUBREDOXIN--NADP+-REDUCTASE-RXN|EC:1.18.1.4									molecular_function											owl:Class	
GO:0030915	biolink:NamedThing	Smc5-Smc6 complex	A conserved complex that contains a heterodimer of SMC proteins (Smc5p and Smc6p, or homologs thereof) and several other proteins, and is involved in DNA repair and maintaining cell cycle arrest following DNA damage. In S. cerevisiae, this is an octameric complex called Mms21-Smc5-Smc6 complex, with at least five of its subunits conserved in fission yeast and humans.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:1902405	biolink:NamedThing	mitotic actomyosin contractile ring localization	Any actomyosin contractile ring localization that is involved in mitotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl	contractile ring localization involved in cell cycle cytokinesis involved in mitotic cell cycle|contractile ring localisation involved in cell cycle cytokinesis involved in mitotic cell cycle							jl	2013-09-12T12:28:05Z					biological_process											owl:Class	
GO:0032688	biolink:NamedThing	negative regulation of interferon-beta production	Any process that stops, prevents, or reduces the frequency, rate, or extent of interferon-beta production.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of IFN-beta production|down regulation of interferon-beta production|down-regulation of interferon-beta production|negative regulation of interferon-beta secretion|negative regulation of interferon-beta biosynthetic process|inhibition of interferon-beta production|downregulation of interferon-beta production											GO:0045358|GO:0035548		biological_process											owl:Class	
GO:0009689	biolink:NamedThing	induction of phytoalexin biosynthetic process	The activation of the chemical reactions and pathways resulting in the formation of phytoalexins, low-molecular mass, lipophilic antimicrobial compounds that accumulate rapidly at sites of incompatible pathogen infection.	tmpzr1t_l9r_go_relaxed.owl	induction of phytoalexin biosynthesis|induction of phytoalexin synthesis|induction of phytoalexin formation|induction of phytoalexin anabolism													biological_process											owl:Class	
GO:0060806	biolink:NamedThing	negative regulation of cell differentiation involved in embryonic placenta development	Any process that decreases the rate, frequency or extent of cell differentiation that contributes to the progression of the placenta over time, from its initial condition to its mature state.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-08-06T02:02:18Z					biological_process											owl:Class	
GO:0004334	biolink:NamedThing	fumarylacetoacetase activity	Catalysis of the reaction: 4-fumarylacetoacetate + H(2)O = acetoacetate + fumarate + H(+).	tmpzr1t_l9r_go_relaxed.owl	4-fumarylacetoacetate fumarylhydrolase activity|fumarylacetoacetate hydrolase activity|beta-diketonase activity				KEGG_REACTION:R01364|MetaCyc:FUMARYLACETOACETASE-RXN|UM-BBD_reactionID:r0107|EC:3.7.1.2|RHEA:10244|Reactome:R-HSA-71181									molecular_function											owl:Class	
GO:0033945	biolink:NamedThing	oligoxyloglucan reducing-end-specific cellobiohydrolase activity	Catalysis of the hydrolysis of cellobiose from the reducing end of xyloglucans consisting of a beta-(1->4) linked glucan carrying alpha-D-xylosyl groups on O-6 of the glucose residues. To be a substrate, the first residue must be unsubstituted, the second residue may bear a xylosyl group, whether further glycosylated or not, and the third residue, which becomes the new terminus by the action of the enzyme, is preferably xylosylated, but this xylose residue must not be further substituted.	tmpzr1t_l9r_go_relaxed.owl	oligoxyloglucan reducing-end cellobiohydrolase activity|oligoxyloglucan reducing end-specific cellobiohydrolase activity				MetaCyc:3.2.1.150-RXN|EC:3.2.1.150									molecular_function											owl:Class	
GO:0007543	biolink:NamedThing	sex determination, somatic-gonadal interaction	The process that mediates the interactions between somatic cells and gonadal cells that ultimately results in the specification of sexual status of the organism.	tmpzr1t_l9r_go_relaxed.owl	sex determination, somatic/gonadal interaction													biological_process											owl:Class	
GO:0007154	biolink:NamedThing	cell communication	Any process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Cell_signaling									biological_process											owl:Class	
GO:1901995	biolink:NamedThing	positive regulation of meiotic cell cycle phase transition	Any process that activates or increases the frequency, rate or extent of meiotic cell cycle phase transition.	tmpzr1t_l9r_go_relaxed.owl	up regulation of cell cycle transition|upregulation of meiotic cell cycle phase transition|activation of cell cycle transition|up-regulation of meiotic cell cycle phase transition|activation of meiotic cell cycle phase transition|upregulation of cell cycle transition|positive regulation of cell cycle transition|up-regulation of cell cycle transition|up regulation of meiotic cell cycle phase transition							jl	2013-03-19T16:15:08Z					biological_process											owl:Class	
GO:0010113	biolink:NamedThing	negative regulation of systemic acquired resistance	Any process that stops, prevents, or reduces the frequency, rate or extent of systemic acquired resistance.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of systemic acquired resistance|downregulation of systemic acquired resistance|down regulation of systemic acquired resistance|inhibition of systemic acquired resistance													biological_process											owl:Class	
GO:0051083	biolink:NamedThing	'de novo' cotranslational protein folding	The process of assisting in the correct noncovalent assembly of the ribosome-bound nascent chains of a multidomain protein whilst other parts of the protein are still being translated.	tmpzr1t_l9r_go_relaxed.owl	multidomain protein assembly|nascent polypeptide association|'de novo' co-translational protein folding											GO:0006444		biological_process											owl:Class	
GO:0006458	biolink:NamedThing	'de novo' protein folding	The process of assisting in the folding of a nascent peptide chain into its correct tertiary structure.	tmpzr1t_l9r_go_relaxed.owl	nascent chain protein folding													biological_process											owl:Class	
GO:0003316	biolink:NamedThing	establishment of myocardial progenitor cell apical/basal polarity	The specification and formation of the apicobasal polarity of an myocardial progenitor cell that contributes to the formation of the heart rudiment.	tmpzr1t_l9r_go_relaxed.owl	myocardial progenitor epithelial polarization							dph	2009-10-27T09:01:26Z					biological_process											owl:Class	
GO:0071970	biolink:NamedThing	fungal-type cell wall (1->3)-beta-D-glucan biosynthetic process	The chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds, found in fungal cell walls.	tmpzr1t_l9r_go_relaxed.owl	fungal-type cell wall beta-1,3-glucan formation|fungal-type cell wall 1,3-beta-D-glucan biosynthetic process|fungal-type cell wall beta-1,3-glucan anabolism|fungal-type cell wall beta-1,3-glucan synthesis|fungal-type cell wall 1,3-beta-glucan formation|fungal-type cell wall beta-1,3-glucan biosynthesis|fungal-type cell wall 1,3-beta-glucan biosynthesis|fungal-type cell wall 1,3-beta-glucan synthesis|fungal-type cell wall 1,3-beta-glucan anabolism|fungal-type cell wall beta-1,3-glucan biosynthetic process							mah	2010-10-18T03:25:56Z					biological_process											owl:Class	
GO:0070880	biolink:NamedThing	fungal-type cell wall beta-glucan biosynthetic process	The chemical reactions and pathways resulting in the formation of beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds, found in the walls of fungal cells.	tmpzr1t_l9r_go_relaxed.owl	fungal-type cell wall beta-glucan formation|fungal-type cell wall beta-glucan anabolism|fungal-type cell wall beta-glucan biosynthesis|fungal-type cell wall beta-glucan synthesis							mah	2009-08-21T02:48:24Z					biological_process											owl:Class	
GO:0071409	biolink:NamedThing	cellular response to cycloheximide	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cycloheximide stimulus. Cycloheximide (actidione) is an antibiotic produced by some Streptomyces species which interferes with protein synthesis in eukaryotes.	tmpzr1t_l9r_go_relaxed.owl	cellular response to actidione							mah	2009-12-14T02:57:24Z					biological_process											owl:Class	
GO:0046898	biolink:NamedThing	response to cycloheximide	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cycloheximide stimulus. Cycloheximide (actidione) is an antibiotic produced by some Streptomyces species which interferes with protein synthesis in eukaryotes.	tmpzr1t_l9r_go_relaxed.owl	response to actidione													biological_process											owl:Class	
GO:1905142	biolink:NamedThing	positive regulation of apical ectodermal ridge formation	Any process that activates or increases the frequency, rate or extent of apical ectodermal ridge formation.	tmpzr1t_l9r_go_relaxed.owl	activation of AER formation|positive regulation of crista ectodermalis apicalis formation|upregulation of apical ectodermal ridge formation|up-regulation of apical ectodermal ridge formation|positive regulation of apical epidermal ridge formation|up regulation of apical epidermal ridge formation|upregulation of AER formation|up-regulation of apical epidermal ridge formation|up-regulation of AER formation|up regulation of apical ectodermal ridge formation|up regulation of crista ectodermalis apicalis formation|upregulation of crista ectodermalis apicalis formation|up regulation of AER formation|positive regulation of AER formation|upregulation of apical epidermal ridge formation|up-regulation of crista ectodermalis apicalis formation							dph	2016-04-13T12:16:57Z					biological_process											owl:Class	
GO:1903429	biolink:NamedThing	regulation of cell maturation	Any process that modulates the frequency, rate or extent of cell maturation.	tmpzr1t_l9r_go_relaxed.owl	regulation of functional differentiation							jl	2014-09-15T13:31:23Z					biological_process											owl:Class	
GO:1990737	biolink:NamedThing	response to manganese-induced endoplasmic reticulum stress	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of endoplasmic reticulum stress caused by a manganese stimulus.	tmpzr1t_l9r_go_relaxed.owl	manganese-induced ER stress response|response to Mn-induced ER stress|response to manganese-induced ER stress							bf	2015-04-30T13:48:45Z					biological_process											owl:Class	
GO:0002015	biolink:NamedThing	regulation of systemic arterial blood pressure by atrial baroreceptor feedback	A process that controls blood pressure by sensing the amount of stretch occurring in the atria.	tmpzr1t_l9r_go_relaxed.owl	atrial baroreceptor regulation of systemic arterial blood pressure|atrial reflex|atrial control of blood pressure|atrial low pressure baroreceptor regulation of blood pressure													biological_process											owl:Class	
GO:0003015	biolink:NamedThing	heart process	A circulatory system process carried out by the heart. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.	tmpzr1t_l9r_go_relaxed.owl	cardiac process													biological_process											owl:Class	
GO:1901507	biolink:NamedThing	negative regulation of acylglycerol transport	Any process that stops, prevents or reduces the frequency, rate or extent of acylglycerol transport.	tmpzr1t_l9r_go_relaxed.owl	inhibition of acylglycerol transport|down-regulation of glyceride transport|negative regulation of glyceride transport|down-regulation of acylglycerol transport|downregulation of acylglycerol transport|inhibition of glyceride transport|downregulation of glyceride transport|down regulation of acylglycerol transport|down regulation of glyceride transport							sart	2012-10-17T11:06:18Z					biological_process											owl:Class	
GO:0004823	biolink:NamedThing	leucine-tRNA ligase activity	Catalysis of the reaction: L-leucine + ATP + tRNA(Leu) = AMP + diphosphate + 2 H(+) + Leu-tRNA(Leu).	tmpzr1t_l9r_go_relaxed.owl	leucyl-transfer RNA synthetase activity|leucine translase activity|leucyl-transfer ribonucleic acid synthetase activity|leucyl-tRNA synthetase activity|leucine-tRNA synthetase activity|leucyl-transfer ribonucleate synthetase activity|L-leucine:tRNALeu ligase (AMP-forming)				KEGG_REACTION:R03657|EC:6.1.1.4|Reactome:R-HSA-379974|MetaCyc:LEUCINE--TRNA-LIGASE-RXN|Reactome:R-HSA-380200|RHEA:11688									molecular_function											owl:Class	
GO:0035489	biolink:NamedThing	guanine/guanine mispair binding	Binding to a double-stranded DNA region containing a G/G mispair.	tmpzr1t_l9r_go_relaxed.owl	G/G mispair binding							bf	2010-04-23T11:16:55Z					molecular_function											owl:Class	
GO:1990220	biolink:NamedThing	GroEL-GroES complex	Bacterial chaperonin complex consisting of a heptameric 10kDa chaperonin subunit GroES and a tetradecameric (2x7) 60kDa chaperonin subunit GroEL. The 60kDa subunit possesses ATPase activity while the holo-enzyme is responsible for the correct folding of proteins.	tmpzr1t_l9r_go_relaxed.owl	bacterial chaperonin ATPase complex|bacterial chaperonin complex							bhm	2013-10-11T09:20:01Z					cellular_component											owl:Class	
GO:0016465	biolink:NamedThing	chaperonin ATPase complex	Multisubunit protein complex with 2x7 (Type I, in most cells) or 2x8 (Type II, in Archaea) ATP-binding sites involved in maintaining an unfolded polypeptide structure before folding or to entry into mitochondria and chloroplasts.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:2000749	biolink:NamedThing	positive regulation of rDNA heterochromatin assembly	Any process that activates or increases the frequency, rate or extent of assembly of rDNA heterochromatin.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of rDNA chromatin silencing|positive regulation of ribosomal DNA heterochromatin assembly|positive regulation of heterochromatic silencing at rDNA|positive regulation of chromatin silencing at rDNA|positive regulation of chromatin silencing at ribosomal DNA	https://github.com/geneontology/go-ontology/issues/19238						pr	2011-06-16T09:43:55Z					biological_process											owl:Class	
GO:1904730	biolink:NamedThing	negative regulation of intestinal lipid absorption	Any process that stops, prevents or reduces the frequency, rate or extent of intestinal lipid absorption.	tmpzr1t_l9r_go_relaxed.owl	downregulation of intestinal lipid absorption|down-regulation of intestinal lipid absorption|down regulation of intestinal lipid absorption|inhibition of intestinal lipid absorption							sl	2015-10-14T15:25:03Z					biological_process											owl:Class	
GO:1904729	biolink:NamedThing	regulation of intestinal lipid absorption	Any process that modulates the frequency, rate or extent of intestinal lipid absorption.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-10-14T15:24:56Z					biological_process											owl:Class	
GO:0017010	biolink:NamedThing	protein-phycourobilin linkage	The linkage of the chromophore phycourobilin to phycoerythrins.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0260									biological_process											owl:Class	
GO:0034140	biolink:NamedThing	negative regulation of toll-like receptor 3 signaling pathway	Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 3 signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of TLR3 signaling pathway|negative regulation of toll-like receptor 3 signalling pathway													biological_process											owl:Class	
GO:0032262	biolink:NamedThing	pyrimidine nucleotide salvage	Any process which produces a pyrimidine nucleotide from derivatives of it, without de novo synthesis.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0006221	biolink:NamedThing	pyrimidine nucleotide biosynthetic process	The chemical reactions and pathways resulting in the formation of a pyrimidine nucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.	tmpzr1t_l9r_go_relaxed.owl	pyrimidine nucleotide synthesis|pyrimidine nucleotide biosynthesis|pyrimidine nucleotide formation|pyrimidine nucleotide anabolism													biological_process											owl:Class	
GO:0045975	biolink:NamedThing	positive regulation of translation, ncRNA-mediated	Any process, mediated by small non-coding RNAs, that activates or increases the rate that mRNAs are effectively translated into protein.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of mRNA translation, ncRNA-mediated|up regulation of mRNA translation, ncRNA-mediated|activation of mRNA translation, ncRNA-mediated|upregulation of mRNA translation, ncRNA-mediated|stimulation of mRNA translation, ncRNA-mediated													biological_process											owl:Class	
GO:0009991	biolink:NamedThing	response to extracellular stimulus	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an extracellular stimulus.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0048768	biolink:NamedThing	root hair cell tip growth	Localized growth of a plant root hair tip by extension of the cell wall.	tmpzr1t_l9r_go_relaxed.owl	root hair tip growth													biological_process											owl:Class	
GO:0009932	biolink:NamedThing	cell tip growth	Growth that occurs specifically at the tip of a cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1902815	biolink:NamedThing	N,N'-diacetylchitobiose import	The directed movement of N,N'-diacetylchitobiose into a cell or organelle.	tmpzr1t_l9r_go_relaxed.owl								tb	2014-03-27T20:58:58Z					biological_process											owl:Class	
GO:0031952	biolink:NamedThing	regulation of protein autophosphorylation	Any process that modulates the frequency, rate or extent of addition of the phosphorylation by a protein of one or more of its own residues.	tmpzr1t_l9r_go_relaxed.owl	regulation of protein amino acid autophosphorylation													biological_process											owl:Class	
GO:0045300	biolink:NamedThing	acyl-[acyl-carrier-protein] desaturase activity	Catalysis of the reaction: stearoyl-[acyl-carrier protein] + reduced acceptor + O2 = oleoyl-[acyl-carrier protein] + acceptor + H2O. The enzyme requires ferredoxin.	tmpzr1t_l9r_go_relaxed.owl	stearyl-ACP desaturase activity|stearyl acyl carrier protein desaturase activity|acyl-[acyl-carrier protein] desaturase activity|acyl-acyl-carrier-protein, hydrogen-donor:oxygen oxidoreductase activity|acyl-acyl-carrier-protein desaturase activity				MetaCyc:PWY-5147|MetaCyc:1.14.19.2-RXN|EC:1.14.19.2	Note that this function was formerly EC:1.14.99.6.								molecular_function											owl:Class	
GO:1901865	biolink:NamedThing	capsorubin catabolic process	The chemical reactions and pathways resulting in the breakdown of capsorubin.	tmpzr1t_l9r_go_relaxed.owl	capsorubin catabolism|capsorubin degradation|capsorubin breakdown							yaf	2013-02-04T10:50:17Z					biological_process											owl:Class	
GO:1901864	biolink:NamedThing	capsorubin metabolic process	The chemical reactions and pathways involving capsorubin.	tmpzr1t_l9r_go_relaxed.owl	capsorubin metabolism							yaf	2013-02-04T10:50:13Z					biological_process											owl:Class	
GO:0045950	biolink:NamedThing	negative regulation of mitotic recombination	Any process that inhibits or decreases the rate of DNA recombination during mitosis.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of mitotic recombination|inhibition of mitotic recombination|downregulation of mitotic recombination|negative regulation of recombination within rDNA repeats|down regulation of mitotic recombination													biological_process											owl:Class	
GO:0070375	biolink:NamedThing	ERK5 cascade	An intracellular protein kinase cascade containing at least ERK5 (also called BMK1; a MAPK), a MEK (a MAPKK) and a MAP3K. The cascade can also contain an additional tier: the upstream MAP4K. The kinases in each tier phosphorylate and activate the kinases in the downstream tier to transmit a signal within a cell.	tmpzr1t_l9r_go_relaxed.owl	ERK5 signaling pathway|MAPK7 cascade|BMK signalling pathway|extracellular signal-regulated kinase 5 cascade|BMK1 cascade|BMK signaling pathway|BMK cascade|big MAP kinase signaling cascade													biological_process											owl:Class	
GO:0006808	biolink:NamedThing	regulation of nitrogen utilization	Any process that modulates the frequency, rate or extent of nitrogen utilization.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0019740	biolink:NamedThing	nitrogen utilization	A series of processes that forms an integrated mechanism by which a cell or an organism detects the depletion of primary nitrogen source, usually ammonia, and then activates genes to scavenge the last traces of the primary nitrogen source and to transport and metabolize alternative nitrogen sources. The utilization process begins when the cell or organism detects nitrogen levels, includes the activation of genes whose products detect, transport or metabolize nitrogen-containing substances, and ends when nitrogen is incorporated into the cell or organism's metabolism.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0014040	biolink:NamedThing	positive regulation of Schwann cell differentiation	Any process that activates or increases the frequency, rate or extent of Schwann cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of Schwann cell differentiation|activation of Schwann cell differentiation|upregulation of Schwann cell differentiation|stimulation of Schwann cell differentiation|up regulation of Schwann cell differentiation													biological_process											owl:Class	
GO:0014037	biolink:NamedThing	Schwann cell differentiation	The process in which a relatively unspecialized cell acquires the specialized features of a Schwann cell. Schwann cells are found in the peripheral nervous system, where they insulate neurons and axons, and regulate the environment in which neurons function.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0010465	biolink:NamedThing	nerve growth factor receptor activity	Combining with nerve growth factor (NGF), to prevent apoptosis in neurons and promote nerve growth, or to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	NGF receptor activity|beta-nerve growth factor receptor activity													molecular_function											owl:Class	
GO:0010845	biolink:NamedThing	positive regulation of reciprocal meiotic recombination	Any process that increases the frequency, rate or extent of recombination during meiosis. Reciprocal meiotic recombination is the cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of meiotic recombination													biological_process											owl:Class	
GO:0021701	biolink:NamedThing	cerebellar Golgi cell differentiation	The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature cerebellar Golgi cell. Differentiation includes the processes involved in commitment of a neuroblast to a Golgi cell fate. A cerebellar Golgi cell is an inhibitory GABAergic interneuron found in the cerebellar cortex.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1901414	biolink:NamedThing	negative regulation of tetrapyrrole biosynthetic process from glycine and succinyl-CoA	Any process that stops, prevents or reduces the frequency, rate or extent of tetrapyrrole biosynthetic process from glycine and succinyl-CoA.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of tetrapyrrole anabolism from glycine and succinyl-CoA|negative regulation of tetrapyrrole biosynthesis from glycine and succinyl-CoA|downregulation of tetrapyrrole anabolism from glycine and succinyl-CoA|down regulation of tetrapyrrole formation from glycine and succinyl-CoA|down regulation of tetrapyrrole biosynthesis from glycine and succinyl-CoA|inhibition of tetrapyrrole biosynthesis from glycine and succinyl-CoA|down regulation of tetrapyrrole synthesis from glycine and succinyl-CoA|inhibition of tetrapyrrole biosynthetic process from glycine and succinyl-CoA|down-regulation of tetrapyrrole formation from glycine and succinyl-CoA|down-regulation of tetrapyrrole biosynthetic process from glycine and succinyl-CoA|inhibition of tetrapyrrole synthesis from glycine and succinyl-CoA|downregulation of tetrapyrrole biosynthetic process from glycine and succinyl-CoA|down-regulation of tetrapyrrole synthesis from glycine and succinyl-CoA|negative regulation of tetrapyrrole formation from glycine and succinyl-CoA|down regulation of tetrapyrrole biosynthetic process from glycine and succinyl-CoA|downregulation of tetrapyrrole formation from glycine and succinyl-CoA|down-regulation of tetrapyrrole biosynthesis from glycine and succinyl-CoA|negative regulation of tetrapyrrole synthesis from glycine and succinyl-CoA|inhibition of tetrapyrrole anabolism from glycine and succinyl-CoA|down regulation of tetrapyrrole anabolism from glycine and succinyl-CoA|negative regulation of tetrapyrrole anabolism from glycine and succinyl-CoA|inhibition of tetrapyrrole formation from glycine and succinyl-CoA|downregulation of tetrapyrrole synthesis from glycine and succinyl-CoA|downregulation of tetrapyrrole biosynthesis from glycine and succinyl-CoA							tt	2012-10-01T16:28:54Z					biological_process											owl:Class	
GO:0033527	biolink:NamedThing	tetrapyrrole biosynthetic process from glycine and succinyl-CoA	The chemical reactions and pathways leading to the formation of tetrapyrroles, natural pigments containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next, from other compounds, including glycine and succinyl-CoA.	tmpzr1t_l9r_go_relaxed.owl	tetrapyrrole synthesis from glycine and succinyl-CoA|tetrapyrrole anabolism from glycine and succinyl-CoA|tetrapyrrole biosynthesis from glycine and succinyl-CoA|tetrapyrrole formation from glycine and succinyl-CoA				MetaCyc:PWY-5189									biological_process											owl:Class	
GO:2000586	biolink:NamedThing	regulation of platelet-derived growth factor receptor-beta signaling pathway	Any process that modulates the frequency, rate or extent of platelet-derived growth factor receptor-beta signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	regulation of betaPDGF receptor signaling pathway|regulation of PDGF receptor-beta signaling pathway|regulation of PDGFR-beta signaling pathway|regulation of platelet-derived growth factor receptor-beta signalling pathway							bf	2011-04-07T03:27:48Z					biological_process											owl:Class	
GO:0035791	biolink:NamedThing	platelet-derived growth factor receptor-beta signaling pathway	A series of molecular signals initiated by the binding of a ligand to a beta-type platelet-derived growth factor receptor (PDGFbeta) on the surface of a signal-receiving cell, and ending with regulation of a downstream cellular process, e.g. transcription.	tmpzr1t_l9r_go_relaxed.owl	platelet-derived growth factor receptor-beta signalling pathway|PDGFR-beta signaling pathway|PDGF receptor-beta signaling pathway|betaPDGF receptor signaling pathway							bf	2011-04-06T10:57:04Z					biological_process											owl:Class	
GO:1904058	biolink:NamedThing	positive regulation of sensory perception of pain	Any process that activates or increases the frequency, rate or extent of sensory perception of pain.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of nociception|activation of sensory perception of pain|upregulation of nociception|up-regulation of sensory perception of pain|positive regulation of perception of physiological pain|activation of nociception|up-regulation of perception of physiological pain|up regulation of perception of physiological pain|activation of perception of physiological pain|upregulation of perception of physiological pain|upregulation of sensory perception of pain|up-regulation of nociception|up regulation of nociception|up regulation of sensory perception of pain							sl	2015-03-18T20:34:03Z					biological_process											owl:Class	
GO:0098719	biolink:NamedThing	sodium ion import across plasma membrane	The directed movement of sodium ions from outside of a cell, across the plasma membrane and into the cytosol.	tmpzr1t_l9r_go_relaxed.owl	sodium ion import into cell|sodium import|sodium ion import							pr	2012-08-03T16:55:52Z			GO:0097369|GO:1990118		biological_process											owl:Class	
GO:0008537	biolink:NamedThing	proteasome activator complex	A multisubunit complex that activates the hydrolysis of small nonubiquitinated peptides by binding to the proteasome core complex.	tmpzr1t_l9r_go_relaxed.owl	PA28													cellular_component											owl:Class	
GO:0022624	biolink:NamedThing	proteasome accessory complex	A protein complex, that caps one or both ends of the proteasome core complex and regulates entry into, or exit from, the proteasome core complex.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:1990730	biolink:NamedThing	VCP-NSFL1C complex	A protein complex between the ATPase VCP (p97) and its cofactor p47 (NSFL1C). In human, the protein complex consists of one homotrimer of NSFL1C/p47 per homohexamer of VCP/p97.	tmpzr1t_l9r_go_relaxed.owl	p97-p47 complex							bf	2015-04-20T12:27:35Z					cellular_component											owl:Class	
GO:0005737	biolink:NamedThing	cytoplasm	The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Cytoplasm									cellular_component											owl:Class	
GO:1901587	biolink:NamedThing	positive regulation of acid-sensing ion channel activity	Any process that activates or increases the frequency, rate or extent of acid-sensing ion channel activity.	tmpzr1t_l9r_go_relaxed.owl	activation of acid-sensing ion channel activity|activation of ASIC activity|positive regulation of ASIC activity|up regulation of ASIC activity|up-regulation of acid-sensing ion channel activity|up-regulation of ASIC activity|upregulation of ASIC activity|upregulation of acid-sensing ion channel activity|up regulation of acid-sensing ion channel activity							jl	2012-11-07T13:37:37Z					biological_process											owl:Class	
GO:0044736	biolink:NamedThing	acid-sensing ion channel activity	Enables the transmembrane transfer of a sodium ion by a neuronal, voltage-insensitive channel that opens when an extracellular proton has been bound by the channel complex.	tmpzr1t_l9r_go_relaxed.owl	ASIC activity				Wikipedia:Acid-sensing_ion_channel|Reactome:R-HSA-2671885			jl	2012-11-06T16:36:37Z					molecular_function											owl:Class	
GO:0046552	biolink:NamedThing	photoreceptor cell fate commitment	The process in which the developmental fate of a cell becomes restricted such that it will develop into a photoreceptor cell. A photoreceptor cell is a cell that responds to incident electromagnetic radiation. Different classes of photoreceptor have different spectral sensitivities and express different photosensitive pigments.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0046530	biolink:NamedThing	photoreceptor cell differentiation	The specialization of organization of a photoreceptor, a cell that responds to incident electromagnetic radiation, particularly visible light. An example of this process is found in Drosophila melanogaster.	tmpzr1t_l9r_go_relaxed.owl												GO:0007467		biological_process											owl:Class	
GO:1900841	biolink:NamedThing	negative regulation of helvolic acid biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of helvolic acid biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of helvolic acid biosynthetic process|down regulation of helvolic acid biosynthetic process|downregulation of helvolic acid biosynthetic process							di	2012-06-07T09:38:57Z					biological_process											owl:Class	
GO:1900812	biolink:NamedThing	helvolic acid biosynthetic process	The chemical reactions and pathways resulting in the formation of helvolic acid.	tmpzr1t_l9r_go_relaxed.owl	Fumigacin anabolism|helvolic acid anabolism|helvolic acid formation|Fumigacin formation|Fumigacin synthesis|helvolic acid synthesis|Fumigacin biosynthetic process|Fumigacin biosynthesis|helvolic acid biosynthesis							di	2012-06-04T10:02:58Z					biological_process											owl:Class	
GO:0048077	biolink:NamedThing	negative regulation of compound eye pigmentation	Any process that stops, prevents, or reduces the frequency, rate or extent of establishment of a pattern of pigment in the compound eye.	tmpzr1t_l9r_go_relaxed.owl	inhibition of eye pigmentation|negative regulation of eye pigmentation|downregulation of eye pigmentation|down-regulation of eye pigmentation|down regulation of eye pigmentation													biological_process											owl:Class	
GO:0048072	biolink:NamedThing	compound eye pigmentation	Establishment of a pattern of pigment in the compound eye.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0090637	biolink:NamedThing	inner dense plaque of desmosome	The desmosomal part containing the C-termini of desmoplakins which interact with the keratin intermediate filaments, serving to tether the intermediate filaments to the plasma membrane.	tmpzr1t_l9r_go_relaxed.owl								tb	2015-04-20T16:10:51Z					cellular_component											owl:Class	
GO:0030057	biolink:NamedThing	desmosome	A cell-cell junction in which: on the cytoplasmic surface of each interacting plasma membrane is a dense plaque composed of a mixture of intracellular anchor proteins; a bundle of keratin intermediate filaments is attached to the surface of each plaque; transmembrane adhesion proteins of the cadherin family bind to the plaques and interact through their extracellular domains to hold the adjacent membranes together by a Ca2+-dependent mechanism.	tmpzr1t_l9r_go_relaxed.owl	spot desmosome|macula adherens				Wikipedia:Desmosome									cellular_component											owl:Class	
GO:1904735	biolink:NamedThing	regulation of fatty acid beta-oxidation using acyl-CoA dehydrogenase	Any process that modulates the frequency, rate or extent of fatty acid beta-oxidation using acyl-CoA dehydrogenase.	tmpzr1t_l9r_go_relaxed.owl								lb	2015-10-15T08:14:51Z					biological_process											owl:Class	
GO:0033539	biolink:NamedThing	fatty acid beta-oxidation using acyl-CoA dehydrogenase	A fatty acid beta-oxidation pathway in which the initial step of each oxidation cycle, which converts an acyl-CoA to a trans-2-enoyl-CoA, is catalyzed by acyl-CoA dehydrogenase; the electrons removed by oxidation pass through the respiratory chain to oxygen and leave H2O as the product. Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and ends when only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively).	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:FAO-PWY									biological_process											owl:Class	
GO:0034260	biolink:NamedThing	negative regulation of GTPase activity	Any process that stops or reduces the rate of GTP hydrolysis by a GTPase.	tmpzr1t_l9r_go_relaxed.owl	inhibition of Ras GTPase activity|downregulation of regulation of Ran GTPase activity|down-regulation of regulation of Ran GTPase activity|inhibition of Rab GTPase activity|down regulation of regulation of Ran GTPase activity|down regulation of Ras GTPase activity|downregulation of GTPase activity|negative regulation of Rab GTPase activity|down regulation of Rho GTPase activity|inhibition of Rho GTPase activity|negative regulation of Ras GTPase activity|down-regulation of Rab GTPase activity|negative regulation of Rho GTPase activity|down-regulation of Ras GTPase activity|downregulation of Ras GTPase activity|down regulation of Rab GTPase activity|inhibition of regulation of Ran GTPase activity|down-regulation of GTPase activity|negative regulation of Ran GTPase activity|down-regulation of Rho GTPase activity|negative regulation of guanosinetriphosphatase activity|downregulation of Rho GTPase activity|downregulation of Rab GTPase activity|inhibition of GTPase activity|down regulation of GTPase activity					An example of this is P2xA in Dictyostelium (UniProt symbol Q86JM7) in PMID:24335649.						GO:1902264|GO:1902881|GO:0034261|GO:0034259		biological_process											owl:Class	
GO:0003924	biolink:NamedThing	GTPase activity	Catalysis of the reaction: GTP + H2O = GDP + phosphate.	tmpzr1t_l9r_go_relaxed.owl	dynamin GTPase activity|ARF small monomeric GTPase activity|Rho small monomeric GTPase activity|heterotrimeric G-protein GTPase, alpha-subunit|GTPase activity, coupled|protein-synthesizing GTPase activity, termination|signal-recognition-particle GTPase activity|protein-synthesizing GTPase activity|hydrolase activity, acting on acid anhydrides, acting on GTP, involved in cellular and subcellular movement|Sar small monomeric GTPase activity|Ran small monomeric GTPase activity|protein-synthesizing GTPase activity, initiation|Ras small monomeric GTPase activity|Rab small monomeric GTPase activity|small monomeric GTPase activity|heterotrimeric G-protein GTPase activity|RHEB small monomeric GTPase activity|protein-synthesizing GTPase activity, elongation|tubulin GTPase activity|heterotrimeric G-protein GTPase, beta-subunit|heterotrimeric G-protein GTPase, gamma-subunit	https://github.com/geneontology/go-ontology/issues/19078			Reactome:R-HSA-5672017|Reactome:R-HSA-8854255|Reactome:R-HSA-5389842|Reactome:R-HSA-421835|Reactome:R-HSA-380979|Reactome:R-HSA-165055|Reactome:R-HSA-170666|Reactome:R-HSA-164381|Reactome:R-HSA-9640195|Reactome:R-HSA-5658231|Reactome:R-HSA-5623513|Reactome:R-HSA-392212|Reactome:R-HSA-8854612|Reactome:R-HSA-177501|Reactome:R-HSA-9649736|Reactome:R-HSA-555065|Reactome:R-HSA-5638006|Reactome:R-HSA-8847883|Reactome:R-HSA-5665809|Reactome:R-HSA-8981353|Reactome:R-HSA-9645598|Reactome:R-HSA-418574|Reactome:R-HSA-167415|Reactome:R-HSA-392133|Reactome:R-HSA-203973|Reactome:R-HSA-8868661|Reactome:R-HSA-5419273|Reactome:R-HSA-2584246|Reactome:R-HSA-1458485|Reactome:R-HSA-170685|Reactome:R-HSA-418582|Reactome:R-HSA-8854173|Reactome:R-HSA-1445143|Reactome:R-HSA-983422|Reactome:R-HSA-432707|Reactome:R-HSA-156923|Reactome:R-HSA-2130725|Reactome:R-HSA-428941|Reactome:R-HSA-6807877|Reactome:R-HSA-5389839|Reactome:R-HSA-5333615|Reactome:R-HSA-6814833|Reactome:R-HSA-170686|Reactome:R-HSA-8982025|Reactome:R-HSA-2130641|Reactome:R-HSA-8982020|Reactome:R-HSA-5694527|Reactome:R-HSA-8854329|Reactome:R-HSA-8982021|RHEA:19669|Reactome:R-HSA-8854604|Reactome:R-HSA-8847534|Reactome:R-HSA-8849082|Reactome:R-HSA-5419279			dph	2015-11-11T12:47:56Z			GO:0061745		molecular_function											owl:Class	
GO:0090658	biolink:NamedThing	cone matrix sheath	A biochemically and structurally distinct domain of the retinal interphotoreceptor matrix that is specifically associated with cone photoreceptor cell inner and outer segments.	tmpzr1t_l9r_go_relaxed.owl								tb	2015-07-15T13:35:32Z					cellular_component											owl:Class	
GO:0033165	biolink:NamedThing	interphotoreceptor matrix	A specialized extracellularc matrix that surrounds the photoreceptors of the retina and lies between them and the apical surface of the retinal pigment epithelium. The IPM has been implicated in several important activities required for photoreceptor function and maintenance.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0042698	biolink:NamedThing	ovulation cycle	The type of sexual cycle seen in females, often with physiologic changes in the endometrium that recur at regular intervals during the reproductive years.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1901679	biolink:NamedThing	nucleotide transmembrane transport	The directed movement of nucleotide across a membrane.	tmpzr1t_l9r_go_relaxed.owl	nucleotide membrane transport					Note that this term is not intended for use in annotating lateral movement within membranes.		pr	2012-11-22T15:43:23Z					biological_process											owl:Class	
GO:2001095	biolink:NamedThing	mannotriose transport	The directed movement of a mannotrioseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl								jl	2011-09-21T02:04:52Z					biological_process											owl:Class	
GO:0008493	biolink:NamedThing	tetracycline transmembrane transporter activity	Enables the transfer of tetracycline from one side of a membrane to the other. Tetracycline is a broad spectrum antibiotic that blocks binding of aminoacyl tRNA to the ribosomes of both Gram-positive and Gram-negative organisms (and those of organelles).	tmpzr1t_l9r_go_relaxed.owl	tetracycline transporter activity|tetracyclin transporter activity													molecular_function											owl:Class	
GO:0015904	biolink:NamedThing	tetracycline transmembrane transport	The directed movement of tetracycline from one side of a membrane to the other. Tetracycline is a broad spectrum antibiotic that blocks binding of aminoacyl tRNA to the ribosomes of both Gram-positive and Gram-negative organisms (and those of organelles).	tmpzr1t_l9r_go_relaxed.owl	tetracyclin transport|tetracycline transport													biological_process											owl:Class	
GO:0060419	biolink:NamedThing	heart growth	The increase in size or mass of the heart.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0045629	biolink:NamedThing	negative regulation of T-helper 2 cell differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of T-helper 2 cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	down regulation of T-helper 2 cell differentiation|down-regulation of T-helper 2 cell differentiation|negative regulation of T-helper 2 cell development|downregulation of T-helper 2 cell differentiation|inhibition of T-helper 2 cell differentiation					Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.								biological_process											owl:Class	
GO:0045064	biolink:NamedThing	T-helper 2 cell differentiation	The process in which a relatively unspecialized T cell acquires specialized features of a T-helper 2 (Th2) cell. A Th2 cell is a CD4-positive, alpha-beta T cell that has the phenotype GATA-3-positive and produces interleukin-4.	tmpzr1t_l9r_go_relaxed.owl	T-helper 2 cell development					Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.								biological_process											owl:Class	
GO:0005622	biolink:NamedThing	intracellular anatomical structure	A component of a cell contained within (but not including) the plasma membrane. In eukaryotes it includes the nucleus and cytoplasm.	tmpzr1t_l9r_go_relaxed.owl	intracellular|protoplasm|nucleocytoplasm|protoplast|internal to cell	https://github.com/geneontology/go-ontology/issues/17776			Wikipedia:Intracellular									cellular_component											owl:Class	
GO:0099566	biolink:NamedThing	regulation of postsynaptic cytosolic calcium ion concentration	Any process that regulates the concentration of calcium in the postsynaptic cytosol.	tmpzr1t_l9r_go_relaxed.owl	regulation of postsynaptic cytosolic calcium levels													biological_process											owl:Class	
GO:0015667	biolink:NamedThing	site-specific DNA-methyltransferase (cytosine-N4-specific) activity	Catalysis of the reaction: S-adenosyl-L-methionine + DNA cytosine = S-adenosyl-L-homocysteine + DNA N4-methylcytosine.	tmpzr1t_l9r_go_relaxed.owl	DNA[cytosine-N4]methyltransferase activity|S-adenosyl-L-methionine:DNA-cytosine 4-N-methyltransferase activity|N(4)-cytosine-specific DNA methylase activity|modification methylase activity|m4C-forming MTase activity|N4-cytosine-specific DNA methylase activity|restriction-modification system activity|S-adenosyl-L-methionine:DNA-cytosine N4-methyltransferase activity				EC:2.1.1.113|RHEA:16857|MetaCyc:2.1.1.113-RXN									molecular_function											owl:Class	
GO:0090124	biolink:NamedThing	N-4 methylation of cytosine	The covalent transfer of a methyl group to N-4 of cytosine in a DNA molecule.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-12-07T02:40:38Z					biological_process											owl:Class	
GO:0032188	biolink:NamedThing	establishment of actomyosin contractile ring localization	The process in which a contractile ring is assembled in a specific location as part of a process of cell cycle cytokinesis.	tmpzr1t_l9r_go_relaxed.owl	actomyosin ring positioning|establishment of contractile ring localization involved in cell cycle cytokinesis|cytokinesis site selection by contractile ring positioning|establishment of contractile ring localisation involved in cell cycle cytokinesis|contractile ring positioning|establishment of contractile ring localization involved in cytokinesis during cell cycle													biological_process											owl:Class	
GO:0008585	biolink:NamedThing	female gonad development	The process whose specific outcome is the progression of the female gonad over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl	ovary development|ovarian development											GO:0061039		biological_process											owl:Class	
GO:0097648	biolink:NamedThing	G protein-coupled receptor complex	A protein complex that contains G protein-coupled receptors.	tmpzr1t_l9r_go_relaxed.owl	G-protein coupled receptor complex							pr	2014-09-10T09:14:30Z					cellular_component											owl:Class	
GO:0003980	biolink:NamedThing	UDP-glucose:glycoprotein glucosyltransferase activity	Catalysis of the addition of UDP-glucose on to asparagine-linked (N-linked) oligosaccharides of the form Man7-9GlcNAc2 on incorrectly folded glycoproteins.	tmpzr1t_l9r_go_relaxed.owl	UGGT activity				Reactome:R-HSA-548884									molecular_function											owl:Class	
GO:0097359	biolink:NamedThing	UDP-glucosylation	The covalent attachment of a UDP-glucose residue to a substrate molecule.	tmpzr1t_l9r_go_relaxed.owl								pr	2012-07-06T02:26:35Z					biological_process											owl:Class	
GO:0002544	biolink:NamedThing	chronic inflammatory response	Inflammation of prolonged duration (weeks or months) in which active inflammation, tissue destruction, and attempts at repair are proceeding simultaneously. Although it may follow acute inflammation, chronic inflammation frequently begins insidiously, as a low-grade, smoldering, often asymptomatic response.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0048289	biolink:NamedThing	isotype switching to IgE isotypes	The switching of activated B cells from IgM biosynthesis to IgE biosynthesis, accomplished through a recombination process involving an intrachromosomal deletion between switch regions that reside 5' of the IgM and IgE constant region gene segments in the immunoglobulin heavy chain locus.	tmpzr1t_l9r_go_relaxed.owl	class switching to IgE isotypes|isotype switch recombination to IgE isotypes|class switch recombination to IgE isotypes													biological_process											owl:Class	
GO:0001802	biolink:NamedThing	type III hypersensitivity	An inflammatory response resulting from recognition of immune complexes via complement or Fc receptors on effector cells leading to activation of neutrophils and other leukocytes and damage to bystander tissue.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Type_III_hypersensitivity	Note that the Arthus reaction is an example of type III hypersensitivity.								biological_process											owl:Class	
GO:0072087	biolink:NamedThing	renal vesicle development	The process whose specific outcome is the progression of the renal vesicle over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. The renal vesicle is the primordial structure of the nephron epithelium, and is formed by the condensation of mesenchymal cells.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-02-08T01:18:31Z					biological_process											owl:Class	
GO:0072009	biolink:NamedThing	nephron epithelium development	The process whose specific outcome is the progression of the nephron epithelium over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. The nephron epithelium is a tissue that covers the surface of a nephron.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-01-25T02:01:39Z					biological_process											owl:Class	
GO:0006401	biolink:NamedThing	RNA catabolic process	The chemical reactions and pathways resulting in the breakdown of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage.	tmpzr1t_l9r_go_relaxed.owl	RNA degradation|RNA catabolism|RNA breakdown													biological_process											owl:Class	
GO:0001814	biolink:NamedThing	negative regulation of antibody-dependent cellular cytotoxicity	Any process that stops, prevents, or reduces the rate of antibody-dependent cellular cytotoxicity.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of antibody dependent cell death|negative regulation of antibody dependent cell killing|inhibition of antibody-dependent cellular cytotoxicity|negative regulation of antibody-dependent cell killing|downregulation of antibody-dependent cellular cytotoxicity|down regulation of antibody-dependent cellular cytotoxicity|down-regulation of antibody-dependent cellular cytotoxicity|negative regulation of antibody-dependent cell death													biological_process											owl:Class	
GO:0010186	biolink:NamedThing	positive regulation of cellular defense response	Any process that activates or increases the frequency, rate or extent of cellular defense response.	tmpzr1t_l9r_go_relaxed.owl	up regulation of cellular defense response|activation of cellular defense response|stimulation of cellular defense response|upregulation of cellular defense response|positive regulation of cellular defence response|up-regulation of cellular defense response													biological_process											owl:Class	
GO:0006968	biolink:NamedThing	cellular defense response	A defense response that is mediated by cells.	tmpzr1t_l9r_go_relaxed.owl	intracellular defence response|intracellular defense response|cellular defence response	https://github.com/geneontology/go-ontology/issues/18111										GO:0016067|GO:0002818|GO:0016066		biological_process											owl:Class	
GO:0015094	biolink:NamedThing	lead ion transmembrane transporter activity	Enables the transfer of lead (Pb) ions from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	zinc, cadmium, cobalt, nickel, lead-efflux ATPase activity													molecular_function											owl:Class	
GO:0015692	biolink:NamedThing	lead ion transport	The directed movement of lead (Pb) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0001941	biolink:NamedThing	postsynaptic membrane organization	A process which results in the assembly, arrangement of constituent parts, or disassembly of a postsynaptic membrane, the specialized area of membrane facing the presynaptic membrane on the tip of the nerve ending and separated from it by a minute cleft (the synaptic cleft).	tmpzr1t_l9r_go_relaxed.owl	post-synaptic membrane organization|postsynaptic membrane organisation													biological_process											owl:Class	
GO:0098973	biolink:NamedThing	structural constituent of postsynaptic actin cytoskeleton	The action of a molecule that contributes to the structural integrity of a postsynaptic actin cytoskeleton.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0098871	biolink:NamedThing	postsynaptic actin cytoskeleton	The actin cytoskeleton that is part of a postsynapse.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0016308	biolink:NamedThing	1-phosphatidylinositol-4-phosphate 5-kinase activity	Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 4-phosphate + ATP = 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + ADP + 2 H(+).	tmpzr1t_l9r_go_relaxed.owl	PIP kinase activity|1-phosphatidylinositol-4-phosphate kinase, class IA|phosphatidylinositol-4-phosphate 5-kinase activity|1-phosphatidylinositol-4-phosphate kinase, class IB|diphosphoinositide kinase activity|phosphatidylinositol 4-phosphate kinase activity|1-phosphatidylinositol-4-phosphate kinase activity|PIP5K|PtdIns(4)P-5-kinase activity|ATP:1-phosphatidyl-1D-myo-inositol-4-phosphate 5-phosphotransferase activity|type I PIP kinase activity				KEGG_REACTION:R03469|EC:2.7.1.68|Reactome:R-HSA-3772436|RHEA:14425|Reactome:R-HSA-8868066|MetaCyc:2.7.1.68-RXN|Reactome:R-HSA-1676082							GO:0004431|GO:0045215		molecular_function											owl:Class	
GO:1900718	biolink:NamedThing	positive regulation of violaceol II biosynthetic process	Any process that activates or increases the frequency, rate or extent of violaceol II biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	activation of violaceol II anabolism|upregulation of violaceol II biosynthesis|upregulation of violaceol II synthesis|activation of violaceol II formation|upregulation of violaceol II anabolism|up regulation of violaceol II biosynthetic process|positive regulation of violaceol II formation|up-regulation of violaceol II anabolism|positive regulation of violaceol II anabolism|up-regulation of violaceol II biosynthesis|upregulation of violaceol II formation|up-regulation of violaceol II synthesis|up-regulation of violaceol II biosynthetic process|up regulation of violaceol II synthesis|up-regulation of violaceol II formation|upregulation of violaceol II biosynthetic process|up regulation of violaceol II biosynthesis|activation of violaceol II biosynthesis|positive regulation of violaceol II synthesis|positive regulation of violaceol II biosynthesis|activation of violaceol II biosynthetic process|up regulation of violaceol II formation|up regulation of violaceol II anabolism|activation of violaceol II synthesis							di	2012-05-22T05:06:06Z					biological_process											owl:Class	
GO:1900593	biolink:NamedThing	violaceol II biosynthetic process	The chemical reactions and pathways resulting in the formation of violaceol II.	tmpzr1t_l9r_go_relaxed.owl	violaceol II formation|violaceol II biosynthesis|violaceol II anabolism|violaceol II synthesis							di	2012-05-15T06:51:51Z					biological_process											owl:Class	
GO:0007229	biolink:NamedThing	integrin-mediated signaling pathway	A series of molecular signals initiated by the binding of extracellular ligand to an integrin on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.	tmpzr1t_l9r_go_relaxed.owl	integrin-mediated signalling pathway													biological_process											owl:Class	
GO:0072240	biolink:NamedThing	metanephric DCT cell differentiation	The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the distal convoluted tubule cells of the metanephros as it progresses from its formation to the mature state.	tmpzr1t_l9r_go_relaxed.owl	metanephric distal convoluted tubule cell differentiation							mah	2010-03-19T03:24:25Z					biological_process											owl:Class	
GO:0003281	biolink:NamedThing	ventricular septum development	The progression of the ventricular septum over time from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl	interventricular septum development|septum inferius development							dph	2009-10-20T10:04:51Z					biological_process											owl:Class	
GO:0003231	biolink:NamedThing	cardiac ventricle development	The process whose specific outcome is the progression of a cardiac ventricle over time, from its formation to the mature structure. A cardiac ventricle receives blood from a cardiac atrium and pumps it out of the heart.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-10-13T11:03:16Z					biological_process											owl:Class	
GO:0000751	biolink:NamedThing	mitotic cell cycle G1 arrest in response to pheromone	The cell cycle regulatory process in which the mitotic cell cycle is halted during G1 as a result of a pheromone stimulus. An example of this process is found in Saccharomyces cerevisiae.	tmpzr1t_l9r_go_relaxed.owl	cell cycle arrest in response to pheromone											GO:0030571		biological_process											owl:Class	
GO:0003152	biolink:NamedThing	morphogenesis of an epithelial fold involved in embryonic heart tube formation	The morphogenetic process in which an epithelial sheet bends along a linear axis, contributing to embryonic heart tube formation.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-09-23T10:10:24Z					biological_process											owl:Class	
GO:0003145	biolink:NamedThing	embryonic heart tube formation via epithelial folding	The process that gives rise to the embryonic heart tube by the cells of the heart field along a linear axis.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-09-22T04:26:03Z					biological_process											owl:Class	
GO:0070865	biolink:NamedThing	investment cone	A cytoskeletal part that consists of a microfilament-rich cone that forms round each nucleus in a spermatogenic cyst and translocates the length of the cyst during sperm individualization.	tmpzr1t_l9r_go_relaxed.owl	F-actin cone							mah	2009-08-19T01:29:33Z					cellular_component											owl:Class	
GO:0019915	biolink:NamedThing	lipid storage	The accumulation and maintenance in cells or tissues of lipids, compounds soluble in organic solvents but insoluble or sparingly soluble in aqueous solvents. Lipid reserves can be accumulated during early developmental stages for mobilization and utilization at later stages of development.	tmpzr1t_l9r_go_relaxed.owl	sequestering of lipids|retention of lipids|lipid retention|sequestration of lipid|storage of lipids|lipid sequestration|lipid sequestering|sequestration of lipids													biological_process											owl:Class	
GO:0004693	biolink:NamedThing	cyclin-dependent protein serine/threonine kinase activity	Cyclin-dependent catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.	tmpzr1t_l9r_go_relaxed.owl	neuronal cdc2-like kinase activity|cyclin-dependent protein kinase, intrinsic catalyst activity|cyclin-dependent kinase-4 activity|cyclin E kinase activity|cyclin D-dependent kinase activity|ATP:cyclin phosphotransferase activity|cyclin-dependent kinase activity|D-type cyclin kinase activity|cdc2 kinase activity|CDK activity|cyclin-dependent protein kinase activity|cyclin D-cdk6 kinase activity|cyclin-dependent kinase-2 activity|CDK, catalytic subunit activity|CDK|cyclin-dependent kinase 6 activity|cyclin-A associated kinase activity|Cdk-activating protein kinase activity|cdk-activating kinase activity				Reactome:R-HSA-1226095|Reactome:R-HSA-1226094|Reactome:R-HSA-69005|Reactome:R-HSA-2984220|Reactome:R-HSA-9624800|Reactome:R-HSA-69754|Reactome:R-HSA-2294600|Reactome:R-HSA-2990882|Reactome:R-HSA-187916|Reactome:R-HSA-174079|Reactome:R-HSA-2172183|Reactome:R-HSA-5244669|Reactome:R-HSA-9008412|Reactome:R-HSA-9009282|Reactome:R-HSA-187520|Reactome:R-HSA-187959|MetaCyc:2.7.11.22-RXN|Reactome:R-HSA-5195402|Reactome:R-HSA-4086410|Reactome:R-HSA-6793661|Reactome:R-HSA-174251|Reactome:R-HSA-69227|Reactome:R-HSA-2245218|Reactome:R-HSA-2220971|Reactome:R-HSA-2468287|Reactome:R-HSA-68944|Reactome:R-HSA-6797606|Reactome:R-HSA-2468293|EC:2.7.11.22|Reactome:R-HSA-174132|Reactome:R-HSA-9686521|Reactome:R-HSA-5692755|Reactome:R-HSA-3788705|Reactome:R-HSA-69756|Reactome:R-HSA-188390|Reactome:R-HSA-4088024|Reactome:R-HSA-174122|Reactome:R-HSA-180047|Reactome:R-HSA-1912391|Reactome:R-HSA-2430533|Reactome:R-HSA-2514854|Reactome:R-HSA-6805109|Reactome:R-HSA-380278|Reactome:R-HSA-187948	This reaction requires the binding of a regulatory cyclin subunit and full activity requires stimulatory phosphorylation by a CDK-activating kinase (CAK).						GO:0016537		molecular_function											owl:Class	
GO:0042555	biolink:NamedThing	MCM complex	A hexameric protein complex required for the initiation and regulation of DNA replication.	tmpzr1t_l9r_go_relaxed.owl	mini-chromosome maintenance complex													cellular_component											owl:Class	
GO:0044171	biolink:NamedThing	host cell smooth endoplasmic reticulum membrane	The lipid bilayer surrounding the host cell smooth endoplasmic reticulum.	tmpzr1t_l9r_go_relaxed.owl	host smooth endoplasmic reticulum membrane							jl	2009-09-04T11:46:00Z					cellular_component											owl:Class	
GO:0044170	biolink:NamedThing	host cell smooth endoplasmic reticulum	The irregular network of unit membranes, visible only by electron microscopy, that occurs in the host cell cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The host smooth ER has no ribosomes adhering to the outer surface.	tmpzr1t_l9r_go_relaxed.owl	host smooth endoplasmic reticulum							jl	2009-09-04T11:33:29Z					cellular_component											owl:Class	
GO:0098794	biolink:NamedThing	postsynapse	The part of a synapse that is part of the post-synaptic cell.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0090252	biolink:NamedThing	epithelium migration involved in imaginal disc-derived wing morphogenesis	The process in which the population of cells that make up a wing epithelium undergo directed movement and contribute to imaginal disc-derived morphogenesis.	tmpzr1t_l9r_go_relaxed.owl								tb	2010-01-22T11:40:46Z					biological_process											owl:Class	
GO:1904034	biolink:NamedThing	positive regulation of t-SNARE clustering	Any process that activates or increases the frequency, rate or extent of t-SNARE clustering.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of t-SNARE clustering|upregulation of t-SNARE clustering|up regulation of t-SNARE clustering|activation of t-SNARE clustering							sl	2015-03-13T21:21:50Z					biological_process											owl:Class	
GO:1990656	biolink:NamedThing	t-SNARE clustering	The clustering process in which t-SNARES are localized to distinct domains in the cell membrane. t-SNAREs are cell surface proteins which are part of secretory microdomain assemblies.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-02-25T00:18:33Z					biological_process											owl:Class	
GO:0032019	biolink:NamedThing	mitochondrial cloud	A prominent mass in the cytoplasm of previtellogenic oocytes. The cloud contains both mitochondria and electron-dense granulofibrillar material (GFM) and is the source of germinal granule material.	tmpzr1t_l9r_go_relaxed.owl	mitochondrial aggregate|Balbiani body													cellular_component											owl:Class	
GO:1904554	biolink:NamedThing	positive regulation of chemotaxis to arachidonic acid	Any process that activates or increases the frequency, rate or extent of chemotaxis to arachidonic acid.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of chemotaxis to arachidonic acid|activation of chemotaxis to arachidonic acid|up regulation of chemotaxis to arachidonic acid|upregulation of chemotaxis to arachidonic acid							sl	2015-08-13T21:08:27Z					biological_process											owl:Class	
GO:0034670	biolink:NamedThing	chemotaxis to arachidonic acid	The directed movement of a motile cell or organism in response to the presence of arachidonic acid.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0003023	biolink:NamedThing	baroreceptor detection of increased arterial stretch	The series of events by which an increase in diameter of an artery is detected and converted to a molecular signal.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0001983	biolink:NamedThing	baroreceptor response to increased systemic arterial blood pressure	The increase in nerve impulses from baroreceptors as a result of increased pressure on an artery that results in an inhibition of sympathetic nerve impulses to peripheral blood vessels.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0035808	biolink:NamedThing	meiotic recombination initiation complex	A protein complex that initiates the formation of double-strand breaks (DSBs) required for meiotic recombination. Consists of a protein that catalyses formation of the double-strand breaks (Spo11 in S. cerevisiae and Rec12 in S. pombe), and a number of accessory proteins.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-04-20T11:52:50Z					cellular_component											owl:Class	
GO:0000794	biolink:NamedThing	condensed nuclear chromosome	A highly compacted molecule of DNA and associated proteins resulting in a cytologically distinct nuclear chromosome.	tmpzr1t_l9r_go_relaxed.owl	meiotic chromosome|nuclear mitotic chromosome					Note that this term and its children can be used to annotate gene products that localize to a mitotic chromosome in an organism that undergoes a 'closed mitosis' in which the nuclear envelope does not break down during mitosis and for gene products that localize to a meiotic chromosome.								cellular_component											owl:Class	
GO:0034085	biolink:NamedThing	establishment of sister chromatid cohesion	The process in which the sister chromatids of a replicated chromosome become associated with each other during S phase.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0043294	biolink:NamedThing	mitochondrial glutamate synthase complex (NADH)	A protein complex, found in the mitochondria, that in yeast consists of a large and a small subunit. Possesses glutamate synthase (NADH) activity.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0061147	biolink:NamedThing	endocardial endothelium development	The progression of the endocardial endothelium over time, from its initial formation to the mature structure. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-06-03T09:15:31Z					biological_process											owl:Class	
GO:0003157	biolink:NamedThing	endocardium development	The process whose specific outcome is the progression of the endocardium over time, from its formation to the mature structure. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-10-01T12:42:27Z					biological_process											owl:Class	
GO:0045635	biolink:NamedThing	negative regulation of melanocyte differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of melanocyte differentiation.	tmpzr1t_l9r_go_relaxed.owl	downregulation of melanocyte differentiation|down regulation of melanocyte differentiation|down-regulation of melanocyte differentiation|negative regulation of melanophore differentiation|inhibition of melanocyte differentiation													biological_process											owl:Class	
GO:0030318	biolink:NamedThing	melanocyte differentiation	The process in which a relatively unspecialized cell acquires specialized features of a melanocyte.	tmpzr1t_l9r_go_relaxed.owl	melanocyte cell differentiation|melanophore differentiation													biological_process											owl:Class	
GO:0021685	biolink:NamedThing	cerebellar granular layer structural organization	The process that contributes to the act of creating the structural organization of the cerebellar granule layer. This process pertains to the physical shaping of a rudimentary structure. The granular layer is the innermost layer of the cerebellar cortex. This layer contains densely packed small neurons, mostly granule cells. Some Golgi cells are found at the outer border. Granule neurons send parallel fibers to the upper molecular layer, where they synapse with Purkinje cell dendrites. Mossy fibers from the pontine nuclei in the white matter synapse with granule cell axons, Golgi cell axons and unipolar brush interneuron axons at cerebellar glomeruli in the granule cell layer.	tmpzr1t_l9r_go_relaxed.owl	cerebellar granular layer structural organisation													biological_process											owl:Class	
GO:0021698	biolink:NamedThing	cerebellar cortex structural organization	The process that contributes to the act of creating the structural organization of the cerebellar cortex. This process pertains to the physical shaping of a rudimentary structure. The cerebellar cortex is a thin mantle of gray matter that covers the surface of each cerebral hemisphere. It has a characteristic morphology with convolutions (gyri) and crevices (sulci) that have specific functions. Six layers of nerve cells and the nerve pathways that connect them comprise the cerebellar cortex. Together, these regions are responsible for the processes of conscious thought, perception, emotion and memory as well as advanced motor function.	tmpzr1t_l9r_go_relaxed.owl	cerebellar cortex structural organisation													biological_process											owl:Class	
GO:0044199	biolink:NamedThing	host cell nuclear envelope	The double lipid bilayer enclosing the host nucleus and separating its contents from the rest of the host cytoplasm; includes the intermembrane space, a gap of width 20-40 nm (also called the perinuclear space).	tmpzr1t_l9r_go_relaxed.owl								jl	2009-10-21T10:56:11Z					cellular_component											owl:Class	
GO:0033645	biolink:NamedThing	host cell endomembrane system	A collection of membranous structures involved in transport within the host cell. The main components of the endomembrane system are endoplasmic reticulum, Golgi bodies, vesicles, cell membrane and nuclear envelope. Members of the endomembrane system pass materials through each other or though the use of vesicles. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0015806	biolink:NamedThing	S-methylmethionine transport	The directed movement of S-methylmethionine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0043057	biolink:NamedThing	backward locomotion	Posterior movement of an organism, e.g. following the direction of the tail of an animal.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0090271	biolink:NamedThing	positive regulation of fibroblast growth factor production	Any process that increases the rate, frequency or extent of the appearance of a fibroblast growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	tmpzr1t_l9r_go_relaxed.owl								tb	2010-02-05T02:33:33Z					biological_process											owl:Class	
GO:0090269	biolink:NamedThing	fibroblast growth factor production	The appearance of a fibroblast growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	tmpzr1t_l9r_go_relaxed.owl								tb	2010-02-05T02:33:33Z					biological_process											owl:Class	
GO:0060073	biolink:NamedThing	micturition	The regulation of body fluids process in which parasympathetic nerves stimulate the bladder wall muscle to contract and expel urine from the body.	tmpzr1t_l9r_go_relaxed.owl	urine voiding|urination				Wikipedia:Urination									biological_process											owl:Class	
GO:0075272	biolink:NamedThing	regulation of zygosporangium development	Any process that modulates the frequency, rate or extent of zygosporangium development, a process in which a fruiting body called zygosporangium is formed.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0075271	biolink:NamedThing	zygosporangium development	The process in which a fruiting body called zygosporangium is formed. A zygosporangium is a thick-walled structure in which spores are produced, and is characteristic of the Zygomycetes.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0072540	biolink:NamedThing	T-helper 17 cell lineage commitment	The process in which a CD4-positive, alpha-beta T cell becomes committed to becoming a T-helper 17 cell, a CD4-positive, alpha-beta T cell with the phenotype RORgamma-t-positive that produces IL-17.	tmpzr1t_l9r_go_relaxed.owl	Th17 fate commitment|T-helper 17 cell fate commitment|Th17 cell lineage commitment							mah	2011-01-17T11:19:48Z					biological_process											owl:Class	
GO:0043567	biolink:NamedThing	regulation of insulin-like growth factor receptor signaling pathway	Any process that modulates the frequency, rate or extent of insulin-like growth factor receptor signaling.	tmpzr1t_l9r_go_relaxed.owl	regulation of insulin-like growth factor receptor signalling pathway|regulation of IGF receptor signaling pathway|regulation of IGF receptor signalling pathway													biological_process											owl:Class	
GO:0048009	biolink:NamedThing	insulin-like growth factor receptor signaling pathway	The series of molecular signals generated as a consequence of the insulin-like growth factor receptor binding to one of its physiological ligands.	tmpzr1t_l9r_go_relaxed.owl	IGF receptor signalling pathway|IGF receptor signaling pathway													biological_process											owl:Class	
GO:0048357	biolink:NamedThing	pedicel mucilage biosynthetic process	The chemical reactions and pathways resulting in the formation of mucilage that occur in the flower stem.	tmpzr1t_l9r_go_relaxed.owl	pedicel mucilage anabolism|pedicel mucilage formation|pedicel mucilage biosynthesis|pedicel mucilage synthesis													biological_process											owl:Class	
GO:0048362	biolink:NamedThing	pedicel mucilage metabolic process	The chemical reactions and pathways involving mucilage that occur in the flower stem.	tmpzr1t_l9r_go_relaxed.owl	pedicel mucilage metabolism													biological_process											owl:Class	
GO:0097568	biolink:NamedThing	median body	A non-membrane bound, semi-organized microtubule array of unknown function found in Giardia species (trophozoite stage). It is located on the dorsal side of the trophozoite, slightly posterior to the ventral disc.	tmpzr1t_l9r_go_relaxed.owl	parabasal body					Note that, due to the asymmetric nature of the Giardia trophozoite, this term is defined spatially as the trophozoite is viewed from the dorsal side, with the two nuclei dorsal to the ventral disc, and the ventral disc toward the anterior.		pr	2014-02-11T13:34:19Z					cellular_component											owl:Class	
GO:0060135	biolink:NamedThing	maternal process involved in female pregnancy	A reproductive process occurring in the mother that allows an embryo or fetus to develop within it.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0042958	biolink:NamedThing	maltodextrin transmembrane transporter activity	Enables the transfer of maltodextrin, any polysaccharide of glucose residues in beta-(1,4) linkage, from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0042956	biolink:NamedThing	maltodextrin transport	The directed movement of maltodextrin, any polysaccharide of glucose residues in beta-(1,4) linkage, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0005789	biolink:NamedThing	endoplasmic reticulum membrane	The lipid bilayer surrounding the endoplasmic reticulum.	tmpzr1t_l9r_go_relaxed.owl	ER membrane													cellular_component											owl:Class	
GO:0000327	biolink:NamedThing	lytic vacuole within protein storage vacuole	A membrane-bounded compartment containing crystals of phytic acid and proteins characteristic of a lytic vacuole, found within a storage vacuole.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0000326	biolink:NamedThing	protein storage vacuole	A storage vacuole that contains a lytic vacuole; identified in plants.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0070946	biolink:NamedThing	neutrophil-mediated killing of gram-positive bacterium	The directed killing of a gram-positive bacterium by a neutrophil.	tmpzr1t_l9r_go_relaxed.owl	neutrophil mediated killing of gram-positive bacterium							mah	2009-10-01T02:04:15Z					biological_process											owl:Class	
GO:0050830	biolink:NamedThing	defense response to Gram-positive bacterium	Reactions triggered in response to the presence of a Gram-positive bacterium that act to protect the cell or organism.	tmpzr1t_l9r_go_relaxed.owl	defence response to Gram-positive bacterium|defence response to Gram-positive bacteria|Gram-positive antibacterial peptide activity|defense response to Gram-positive bacteria													biological_process											owl:Class	
GO:0008286	biolink:NamedThing	insulin receptor signaling pathway	The series of molecular signals generated as a consequence of the insulin receptor binding to insulin.	tmpzr1t_l9r_go_relaxed.owl	insulin receptor signalling pathway|daf-2 receptor signaling pathway													biological_process											owl:Class	
GO:0046663	biolink:NamedThing	dorsal closure, leading edge cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a leading edge cell, the dorsal-most cells of the epidermis that migrates during dorsal closure.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0007391	biolink:NamedThing	dorsal closure	The process during Drosophila embryogenesis whereby the ectodermal cells of the lateral epithelium stretch in a coordinated fashion to internalize the amnioserosa cells and close the embryo dorsally.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0098785	biolink:NamedThing	biofilm matrix assembly	A process that results in the assembly of a biofilm matrix.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0042710	biolink:NamedThing	biofilm formation	A process in which planktonically growing microorganisms grow at a liquid-air interface or on a solid substrate under the flow of a liquid and produce extracellular polymers that facilitate matrix formation, resulting in a change in the organisms' growth rate and gene transcription.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/17727												biological_process											owl:Class	
GO:0032624	biolink:NamedThing	interleukin-20 production	The appearance of interleukin-20 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	tmpzr1t_l9r_go_relaxed.owl	ZCYTO10 production|IL-20 production|interleukin-20 biosynthetic process|interleukin-20 secretion											GO:0042237|GO:0072618		biological_process											owl:Class	
GO:0006413	biolink:NamedThing	translational initiation	The process preceding formation of the peptide bond between the first two amino acids of a protein. This includes the formation of a complex of the ribosome, mRNA or circRNA, and an initiation complex that contains the first aminoacyl-tRNA.	tmpzr1t_l9r_go_relaxed.owl	biopolymerization|translation initiation|protein synthesis initiation|biopolymerisation											GO:0006440|GO:0006454		biological_process											owl:Class	
GO:1990500	biolink:NamedThing	eif4e-cup complex	A protein complex that causes translational repression in Drosophila. Prevents assembly of ribosomes at the mRNA by interfacing with a sequence-specific RNA-binding protein leading to recruitment of the CCR4 complex and consequently, reduction of the mRNA's poly(A) tail length. The complex is also required for dorso-ventral pattern formation in the embryo.	tmpzr1t_l9r_go_relaxed.owl	eukaryotic translation initiation factor 4E-cup complex					An example of this is Eif4e in drome (P48598) in PMID:14723848 (inferred from physical interaction).		bhm	2014-09-30T12:31:49Z					cellular_component											owl:Class	
GO:0000932	biolink:NamedThing	P-body	A focus in the cytoplasm where mRNAs may become inactivated by decapping or some other mechanism. Protein and RNA localized to these foci are involved in mRNA degradation, nonsense-mediated mRNA decay (NMD), translational repression, and RNA-mediated gene silencing.	tmpzr1t_l9r_go_relaxed.owl	cytoplasmic mRNA processing body|P body|cytoplasmic foci				Wikipedia:P_body									cellular_component											owl:Class	
GO:0032332	biolink:NamedThing	positive regulation of chondrocyte differentiation	Any process that activates or increases the frequency, rate or extent of chondrocyte differentiation.	tmpzr1t_l9r_go_relaxed.owl	up regulation of chondrocyte differentiation|activation of chondrocyte differentiation|stimulation of chondrocyte differentiation|up-regulation of chondrocyte differentiation|upregulation of chondrocyte differentiation													biological_process											owl:Class	
GO:0002062	biolink:NamedThing	chondrocyte differentiation	The process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte. A chondrocyte is a polymorphic cell that forms cartilage.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0003421	biolink:NamedThing	growth plate cartilage axis specification	The establishment, maintenance and elaboration of the columnar cartilage along the axis of a long bone that contributes to bone growth.	tmpzr1t_l9r_go_relaxed.owl	growth plate cartilage axis determination							dph	2009-12-22T09:16:33Z					biological_process											owl:Class	
GO:0003422	biolink:NamedThing	growth plate cartilage morphogenesis	The process in which the anatomical structures of growth plate cartilage are generated and organized.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-12-22T09:21:30Z					biological_process											owl:Class	
GO:0043678	biolink:NamedThing	intine	The innermost of the major layers of the pollen grain wall which underlies the exine and borders the cytoplasm.	tmpzr1t_l9r_go_relaxed.owl						Note that the intine is not acetolysis resistant and is therefore absent in conventionally prepared palynological material.								cellular_component											owl:Class	
GO:0043667	biolink:NamedThing	pollen wall	The wall surrounding a mature pollen grain; a multilayered structure consisting of a pectocellulosic intine surrounded by a sporopollenin-based exine, which itself contains two layers, the inner nexine and the outer sexine.	tmpzr1t_l9r_go_relaxed.owl	microspore wall													cellular_component											owl:Class	
GO:0060316	biolink:NamedThing	positive regulation of ryanodine-sensitive calcium-release channel activity	Any process that increases the activity of a ryanodine-sensitive calcium-release channel. The ryanodine-sensitive calcium-release channel catalyzes the transmembrane transfer of a calcium ion by a channel that opens when a ryanodine class ligand has been bound by the channel complex or one of its constituent parts.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0005219	biolink:NamedThing	ryanodine-sensitive calcium-release channel activity	Enables the transmembrane transfer of a calcium ion by a channel that opens when a ryanodine class ligand has been bound by the channel complex or one of its constituent parts.	tmpzr1t_l9r_go_relaxed.owl	ryanodine receptor|caffeine-sensitive calcium-release channel				Reactome:R-HSA-2855020									molecular_function											owl:Class	
GO:0030991	biolink:NamedThing	intraciliary transport particle A	The smaller subcomplex of the intraciliary transport particle; characterized complexes have molecular weights of 710-760 kDa.	tmpzr1t_l9r_go_relaxed.owl	intraflagellar transport complex A|IFT complex A|IFT A complex|intraflagellar transport particle A					Note that we deem cilia and microtubule-based flagella to be equivalent.								cellular_component											owl:Class	
GO:0030990	biolink:NamedThing	intraciliary transport particle	A nonmembrane-bound oligomeric protein complex that participates in bidirectional transport of molecules (cargo) along axonemal microtubules.	tmpzr1t_l9r_go_relaxed.owl	intraflagellar transport particle|intraflagellar transport complex|IFT complex					Note that we deem cilia and microtubule-based flagella to be equivalent.								cellular_component											owl:Class	
GO:0005634	biolink:NamedThing	nucleus	A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.	tmpzr1t_l9r_go_relaxed.owl	horsetail nucleus|cell nucleus				Wikipedia:Cell_nucleus|NIF_Subcellular:sao1702920020									cellular_component											owl:Class	
GO:0003129	biolink:NamedThing	heart induction	The close range interaction between mesoderm and endoderm or ectoderm that causes cells to change their fates and specify the development of the heart.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-09-22T02:58:41Z					biological_process											owl:Class	
GO:0071770	biolink:NamedThing	DIM/DIP cell wall layer assembly	The aggregation, arrangement and bonding together of a set of components, including (phenyl)phthiocerol, phthiodiolone, phthiotriol dimycocerosate and diphthioceranate, to form the DIM/DIP layer of the Actinobacterium-type cell wall.	tmpzr1t_l9r_go_relaxed.owl	DIM/DIP cell wall layer biogenesis|DIM cell wall layer assembly|PDIM cell wall layer assembly							mah	2010-03-29T04:47:19Z					biological_process											owl:Class	
GO:0071766	biolink:NamedThing	Actinobacterium-type cell wall biogenesis	A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cell wall of the type found in Actinobacteria. The cell wall is the rigid or semi-rigid envelope lying outside the cell membrane. Actinobacterial cell walls contain characteristic mycolic acids, of which some are covalently linked to the cell wall peptidoglycan and others accumulate at the cell surface.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-03-29T04:12:51Z					biological_process											owl:Class	
GO:0090592	biolink:NamedThing	DNA synthesis involved in DNA replication	Synthesis of DNA that is a part of the process of duplicating one or more molecules of DNA.	tmpzr1t_l9r_go_relaxed.owl								tb	2014-06-06T13:54:36Z					biological_process											owl:Class	
GO:0006260	biolink:NamedThing	DNA replication	The cellular metabolic process in which a cell duplicates one or more molecules of DNA. DNA replication begins when specific sequences, known as origins of replication, are recognized and bound by initiation proteins, and ends when the original DNA molecule has been completely duplicated and the copies topologically separated. The unit of replication usually corresponds to the genome of the cell, an organelle, or a virus. The template for replication can either be an existing DNA molecule or RNA.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:DNA_replication	DNA biosynthesis is only part of this process. See also the biological process terms 'DNA-dependent DNA replication ; GO:0006261' and 'RNA-dependent DNA replication ; GO:0006278'.						GO:0055133		biological_process											owl:Class	
GO:0099703	biolink:NamedThing	induction of synaptic vesicle exocytosis by positive regulation of presynaptic cytosolic calcium ion concentration	The induction of synaptic vesicle release by any process that leads to a rise in intracellular calcium ion concentration at the presynapse.  This is the first step in synaptic transmission.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0086060	biolink:NamedThing	voltage-gated sodium channel activity involved in AV node cell action potential	Enables the transmembrane transfer of a sodium ion by a voltage-gated channel through the plasma membrane of an AV node cardiac muscle cell contributing to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.	tmpzr1t_l9r_go_relaxed.owl	voltage-gated sodium channel activity involved in AV node cardiac muscle cell action potential|voltage-gated sodium channel activity involved in atrioventricular node cardiac muscle cell action potential							dph	2011-11-17T12:52:48Z					molecular_function											owl:Class	
GO:0086045	biolink:NamedThing	membrane depolarization during AV node cell action potential	The process in which AV node cardiac muscle cell membrane potential changes in the depolarizing direction from the negative resting potential towards the positive membrane potential that will be the peak of the action potential.	tmpzr1t_l9r_go_relaxed.owl	membrane depolarization during atrioventricular node cardiac muscle cell action potential|membrane depolarization during AV node cardiac muscle cell action potential							dph	2011-11-16T10:45:18Z					biological_process											owl:Class	
GO:0048690	biolink:NamedThing	regulation of axon extension involved in regeneration	Any process that modulates the frequency, rate or extent of axon extension involved in regeneration.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1990633	biolink:NamedThing	mutator focus	A type of punctate focus localized to the perinuclear region of germline cytoplasm in C. elegans. Mutator foci are required for RNA interference (RNAi) and serve as sites of small inhibitory RNA (siRNA) amplification. As such, proteins that localize to mutator foci include RNA-directed RNA polymerases (RdRPs) and beta-nucleotidyltransferases. Mutator foci are distinct from, but adjacent to or partially overlap, P granules.	tmpzr1t_l9r_go_relaxed.owl								kmv	2015-02-10T20:24:02Z					cellular_component											owl:Class	
GO:0048471	biolink:NamedThing	perinuclear region of cytoplasm	Cytoplasm situated near, or occurring around, the nucleus.	tmpzr1t_l9r_go_relaxed.owl						Note that this term should not be confused with the cellular component term 'nuclear membrane lumen ; GO:0005641', which has the synonym 'perinuclear space'.								cellular_component											owl:Class	
GO:0072597	biolink:NamedThing	maintenance of protein location in chloroplast	Any process in which a protein is maintained in a specific location in a chloroplast, and is prevented from moving elsewhere.	tmpzr1t_l9r_go_relaxed.owl								mah	2011-02-14T02:17:48Z					biological_process											owl:Class	
GO:0060108	biolink:NamedThing	annular furrow extracellular matrix	The extracellular matrix part that is a regularly spaced indentation in the outer cortical layer of the cuticle. The pattern of annular furrows corresponds to sites of invaginations in hypodermal cell membranes that, in turn, correspond to submembranous regions where actin microfilament bundles assemble early in lethargus, the first phase of the molting cycle in which activity and feeding decline.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0060106	biolink:NamedThing	cortical layer of collagen and cuticulin-based cuticle extracellular matrix	The cuticle layer that lies directly beneath the lipid-containing epicuticle. The cortical layer contains collagens and insoluble, non-collagenous cuticulins and is characterized by a distinct annular pattern consisting of regularly spaced annular ridges delineated by annular furrows. An example of this component is found in Caenorhabditis elegans.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0033078	biolink:NamedThing	extrathymic T cell differentiation	The process in which a precursor cell type acquires the specialized features of a T cell via a differentiation pathway independent of the thymus.	tmpzr1t_l9r_go_relaxed.owl	extrathymic T cell development					Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.								biological_process											owl:Class	
GO:0021639	biolink:NamedThing	trochlear nerve morphogenesis	The process in which the anatomical structure of the trochlear nerve is generated and organized. The trochlear nerve is a motor nerve and is the only cranial nerve to exit the brain dorsally. The trochlear nerve innervates the superior oblique muscle.	tmpzr1t_l9r_go_relaxed.owl	CH IV morphogenesis													biological_process											owl:Class	
GO:1902297	biolink:NamedThing	cell cycle DNA replication DNA unwinding	Any DNA unwinding that is involved in cell cycle DNA replication.	tmpzr1t_l9r_go_relaxed.owl	DNA unwinding factor involved in cell cycle DNA replication|DNA unwinding during replication involved in cell cycle DNA replication|DNA unwinding involved in cell cycle DNA replication							jl	2013-07-10T11:47:10Z					biological_process											owl:Class	
GO:0045636	biolink:NamedThing	positive regulation of melanocyte differentiation	Any process that activates or increases the frequency, rate or extent of melanocyte differentiation.	tmpzr1t_l9r_go_relaxed.owl	stimulation of melanocyte differentiation|upregulation of melanocyte differentiation|up regulation of melanocyte differentiation|activation of melanocyte differentiation|positive regulation of melanophore differentiation|up-regulation of melanocyte differentiation													biological_process											owl:Class	
GO:0090171	biolink:NamedThing	chondrocyte morphogenesis	The process in which the structures of a chondrocyte are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a chondrocyte.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-12-11T10:36:02Z					biological_process											owl:Class	
GO:0002063	biolink:NamedThing	chondrocyte development	The process whose specific outcome is the progression of a chondrocyte over time, from its commitment to its mature state. Chondrocyte development does not include the steps involved in committing a chondroblast to a chondrocyte fate.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0006963	biolink:NamedThing	positive regulation of antibacterial peptide biosynthetic process	Any process that activates or increases the frequency, rate, or extent of antibacterial peptide biosynthesis.	tmpzr1t_l9r_go_relaxed.owl	activation of antibacterial peptide biosynthetic process|upregulation of antibacterial peptide biosynthetic process|up regulation of antibacterial peptide biosynthetic process|antibacterial polypeptide induction|up-regulation of antibacterial peptide biosynthetic process|antibacterial peptide induction|stimulation of antibacterial peptide biosynthetic process													biological_process											owl:Class	
GO:0045123	biolink:NamedThing	cellular extravasation	The migration of a leukocyte from the blood vessels into the surrounding tissue.	tmpzr1t_l9r_go_relaxed.owl	immune cell cellular extravasation|leucocyte cellular extravasation|transendothelial leukocyte migration|leukocyte cellular extravasation				Wikipedia:Leukocyte_extravasation									biological_process											owl:Class	
GO:0060662	biolink:NamedThing	salivary gland cavitation	The process in which the solid core of salivary epithelium gives rise to the hollow tube of the gland.	tmpzr1t_l9r_go_relaxed.owl	salivary gland invagination							dph	2009-06-01T08:22:55Z					biological_process											owl:Class	
GO:0007435	biolink:NamedThing	salivary gland morphogenesis	The process in which the anatomical structures of the salivary gland are generated and organized.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0071660	biolink:NamedThing	positive regulation of IP-10 production	Any process that activates or increases the frequency, rate, or extent of production of IP-10.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of CXCL10 production|positive regulation of chemokine (C-C motif) ligand 10 production							mah	2010-02-12T10:41:14Z					biological_process											owl:Class	
GO:0071612	biolink:NamedThing	IP-10 production	The appearance of IP-10 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	tmpzr1t_l9r_go_relaxed.owl	chemokine (C-C motif) ligand 10 production|CXCL10 production							mah	2010-02-05T04:43:56Z					biological_process											owl:Class	
GO:0044090	biolink:NamedThing	positive regulation of vacuole organization	Any process that activates or increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a vacuole.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of vacuole biogenesis|positive regulation of vacuole organisation													biological_process											owl:Class	
GO:0098793	biolink:NamedThing	presynapse	The part of a synapse that is part of the presynaptic cell.	tmpzr1t_l9r_go_relaxed.owl	presynaptic terminal													cellular_component											owl:Class	
GO:2000503	biolink:NamedThing	positive regulation of natural killer cell chemotaxis	Any process that activates or increases the frequency, rate or extent of natural killer cell chemotaxis.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-03-21T10:09:38Z					biological_process											owl:Class	
GO:0035747	biolink:NamedThing	natural killer cell chemotaxis	The directed movement of a natural killer cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).	tmpzr1t_l9r_go_relaxed.owl								bf	2011-03-17T02:40:10Z					biological_process											owl:Class	
GO:0002040	biolink:NamedThing	sprouting angiogenesis	The extension of new blood vessels from existing vessels into avascular tissues, this process includes the specialization of endothelial cells into leading tip and stalk cells, proliferation and migration of the endothelial cells and cell adhesion resulting in angiogenic sprout fusion or lumen formation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0061556	biolink:NamedThing	trigeminal ganglion morphogenesis	The process in which the anatomical structure of a trigeminal ganglion is generated and organized.	tmpzr1t_l9r_go_relaxed.owl	trigeminal ganglia morphogenesis							dph	2013-07-10T08:57:12Z					biological_process											owl:Class	
GO:0061551	biolink:NamedThing	trigeminal ganglion development	The process whose specific outcome is the progression of a trigeminal ganglion over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl	trigeminal ganglia development							dph	2013-07-10T08:42:19Z					biological_process											owl:Class	
GO:2000502	biolink:NamedThing	negative regulation of natural killer cell chemotaxis	Any process that stops, prevents or reduces the frequency, rate or extent of natural killer cell chemotaxis.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-03-21T10:09:32Z					biological_process											owl:Class	
GO:0021699	biolink:NamedThing	cerebellar cortex maturation	A developmental process, independent of morphogenetic (shape) change, that is required for the cerebellar cortex to attain its fully functional state. The cerebellar cortex is a thin mantle of gray matter that covers the surface of each cerebral hemisphere. It has a characteristic morphology with convolutions (gyri) and crevices (sulci) that have specific functions. Six layers of nerve cells and the nerve pathways that connect them comprise the cerebellar cortex. Together, these regions are responsible for the processes of conscious thought, perception, emotion and memory as well as advanced motor function.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1901228	biolink:NamedThing	positive regulation of transcription from RNA polymerase II promoter involved in heart development	Any positive regulation of transcription from RNA polymerase II promoter that is involved in heart development.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of gene-specific transcription from RNA polymerase II promoter involved in cardiac development|upregulation of transcription from RNA polymerase II promoter involved in cardiac development|up-regulation of transcription from RNA polymerase II promoter involved in heart development|stimulation of global transcription from RNA polymerase II promoter involved in heart development|stimulation of transcription from RNA polymerase II promoter involved in cardiac development|activation of transcription from RNA polymerase II promoter involved in dorsal vessel development|up regulation of transcription from RNA polymerase II promoter involved in cardiac development|upregulation of transcription from RNA polymerase II promoter involved in heart development|up regulation of global transcription from RNA polymerase II promoter involved in cardiac development|activation of global transcription from RNA polymerase II promoter involved in heart development|up regulation of global transcription from RNA polymerase II promoter involved in heart development|positive regulation of global transcription from Pol II promoter involved in dorsal vessel development|positive regulation of transcription from Pol II promoter involved in cardiac development|up regulation of transcription from RNA polymerase II promoter involved in heart development|up regulation of transcription from RNA polymerase II promoter involved in dorsal vessel development|positive regulation of transcription from RNA polymerase II promoter involved in cardiac development|stimulation of transcription from RNA polymerase II promoter involved in dorsal vessel development|up-regulation of global transcription from RNA polymerase II promoter involved in heart development|stimulation of global transcription from RNA polymerase II promoter involved in dorsal vessel development|positive regulation of transcription from RNA polymerase II promoter involved in dorsal vessel development|positive regulation of transcription from Pol II promoter involved in heart development|up-regulation of transcription from RNA polymerase II promoter involved in dorsal vessel development|activation of transcription from RNA polymerase II promoter involved in cardiac development|upregulation of transcription from RNA polymerase II promoter involved in dorsal vessel development|up regulation of global transcription from RNA polymerase II promoter involved in dorsal vessel development|upregulation of global transcription from RNA polymerase II promoter involved in dorsal vessel development|upregulation of global transcription from RNA polymerase II promoter involved in cardiac development|upregulation of global transcription from RNA polymerase II promoter involved in heart development|positive regulation of gene-specific transcription from RNA polymerase II promoter involved in heart development|positive regulation of global transcription from Pol II promoter involved in cardiac development|stimulation of global transcription from RNA polymerase II promoter involved in cardiac development|positive regulation of transcription from Pol II promoter involved in dorsal vessel development|activation of global transcription from RNA polymerase II promoter involved in dorsal vessel development|positive regulation of gene-specific transcription from RNA polymerase II promoter involved in dorsal vessel development|activation of global transcription from RNA polymerase II promoter involved in cardiac development|up-regulation of transcription from RNA polymerase II promoter involved in cardiac development|up-regulation of global transcription from RNA polymerase II promoter involved in cardiac development|up-regulation of global transcription from RNA polymerase II promoter involved in dorsal vessel development|stimulation of transcription from RNA polymerase II promoter involved in heart development|activation of transcription from RNA polymerase II promoter involved in heart development|positive regulation of global transcription from Pol II promoter involved in heart development							pr	2012-08-07T12:53:01Z					biological_process											owl:Class	
GO:1905364	biolink:NamedThing	regulation of endosomal vesicle fusion	Any process that modulates the frequency, rate or extent of endosomal vesicle fusion.	tmpzr1t_l9r_go_relaxed.owl	regulation of endosome vesicle fusion							bc	2016-08-16T11:40:36Z					biological_process											owl:Class	
GO:0034058	biolink:NamedThing	endosomal vesicle fusion	The homotypic fusion of endocytic vesicles to form or add to an early endosome.	tmpzr1t_l9r_go_relaxed.owl	endosome vesicle fusion													biological_process											owl:Class	
GO:1903057	biolink:NamedThing	negative regulation of melanosome organization	Any process that stops, prevents or reduces the frequency, rate or extent of melanosome organization.	tmpzr1t_l9r_go_relaxed.owl	down regulation of melanosome organisation|down regulation of melanosome organization and biogenesis|inhibition of melanosome organization|downregulation of melanosome organisation|down regulation of melanosome organization|downregulation of melanosome organization|negative regulation of melanosome organization and biogenesis|negative regulation of melanosome organisation|down-regulation of melanosome organization and biogenesis|down-regulation of melanosome organisation|inhibition of melanosome organisation|downregulation of melanosome organization and biogenesis|inhibition of melanosome organization and biogenesis|down-regulation of melanosome organization					Lack of the transcription factor Zeb2 Q9R0G7 leads to spherical melanosomes with irregular borders, in contrast to the rod-shaped melanosomes of ZEB2MCWT hair follicles.		rl	2014-05-27T13:27:55Z					biological_process											owl:Class	
GO:0032438	biolink:NamedThing	melanosome organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a melanosome. A melanosome is a tissue-specific, membrane-bounded cytoplasmic organelle within which melanin pigments are synthesized and stored.	tmpzr1t_l9r_go_relaxed.owl	melanosome organization and biogenesis|melanosome organisation													biological_process											owl:Class	
GO:1900220	biolink:NamedThing	semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis	Any semaphorin-plexin signaling pathway that contributes to bone trabecula morphogenesis.	tmpzr1t_l9r_go_relaxed.owl	semaphorin-plexin signaling pathway of bone trabecula morphogenesis|semaphorin-plexin signalling pathway of bone trabecula morphogenesis							vk	2012-03-22T01:13:56Z					biological_process											owl:Class	
GO:0005930	biolink:NamedThing	axoneme	The bundle of microtubules and associated proteins that forms the core of cilia (also called flagella) in eukaryotic cells and is responsible for their movements.	tmpzr1t_l9r_go_relaxed.owl	cilium axoneme|flagellar axoneme|flagellum axoneme|ciliary axoneme				Wikipedia:Axoneme	Note that cilia and eukaryotic flagella are deemed to be equivalent. In diplomonad species, such as Giardia, the axoneme may extend intracellularly up to 5um away from the plane of the plasma membrane.						GO:0035086|GO:0035085		cellular_component											owl:Class	
GO:0061719	biolink:NamedThing	glucose catabolic process to pyruvate utilizing ADP	The chemical reactions and pathways resulting in the breakdown of glucose into pyruvate, with the concomitant production of a small amount of ATP and the utilization of ADP in the initial kinase reactions.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:P341-PWY			dph	2015-06-30T13:23:42Z					biological_process											owl:Class	
GO:0004332	biolink:NamedThing	fructose-bisphosphate aldolase activity	Catalysis of the reaction: D-fructose 1,6-bisphosphate = glycerone phosphate + D-glyceraldehyde-3-phosphate.	tmpzr1t_l9r_go_relaxed.owl	D-fructose-1,6-bisphosphate D-glyceraldehyde-3-phosphate-lyase (glycerone-phosphate-forming)|SMALDO|fructose 1,6-diphosphate aldolase activity|phosphofructoaldolase activity|fructose-1,6-bisphosphate triosephosphate-lyase activity|aldolase activity|zymohexase activity|fructose 1-monophosphate aldolase activity|1,6-diphosphofructose aldolase activity|D-fructose-1,6-bisphosphate D-glyceraldehyde-3-phosphate-lyase activity|fructoaldolase activity|diphosphofructose aldolase activity|fructose diphosphate aldolase activity|fructose 1-phosphate aldolase activity|ketose 1-phosphate aldolase activity				RHEA:14729|Reactome:R-HSA-71495|Reactome:R-HSA-71496|MetaCyc:F16ALDOLASE-RXN|EC:4.1.2.13									molecular_function											owl:Class	
GO:0002324	biolink:NamedThing	natural killer cell proliferation involved in immune response	The expansion of a natural killer cell population by cell division as part of an immune response.	tmpzr1t_l9r_go_relaxed.owl	NK cell proliferation during immune response|natural killer cell proliferation during immune response													biological_process											owl:Class	
GO:0042950	biolink:NamedThing	salicin transmembrane transporter activity	Enables the transfer of salicin (saligenin-beta-D-glucopyranoside), a glucoside of o-hydroxybenzylalcohol, from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0042948	biolink:NamedThing	salicin transport	The directed movement of salicin (saligenin-beta-D-glucopyranoside), a glucoside of o-hydroxybenzylalcohol, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0052885	biolink:NamedThing	all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity	Catalysis of the reaction: H(2)O + all-trans-retinyl ester = 11-cis-retinol + fatty acid.	tmpzr1t_l9r_go_relaxed.owl	retinol isomerase activity|retinoid isomerohydrolase activity|all-trans-retinol isomerase:hydrolase activity|all-trans-retinyl ester acylhydrolase, 11-cis retinol forming activity|all-trans-retinylester 11-cis isomerohydrolase activity				EC:3.1.1.64|RHEA:31771|KEGG_REACTION:R08388|MetaCyc:RXN-12550									molecular_function											owl:Class	
GO:0042572	biolink:NamedThing	retinol metabolic process	The chemical reactions and pathways involving retinol, one of the three compounds that makes up vitamin A.	tmpzr1t_l9r_go_relaxed.owl	retinol metabolism|vitamin A1 alcohol metabolism|vitamin A1 alcohol metabolic process|vitamin A1 metabolism|vitamin A1 metabolic process				Wikipedia:Retinol									biological_process											owl:Class	
GO:0061293	biolink:NamedThing	canonical Wnt signaling pathway involved in mesonephric nephron development	The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes that contribute to the progression of the mesonephric nephron over time. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes.	tmpzr1t_l9r_go_relaxed.owl	canonical Wnt receptor signalling pathway involved in mesonephric nephron development|canonical Wnt-activated signaling pathway involved in mesonephric nephron development|canonical Wnt receptor signaling pathway involved in mesonephric nephron development							dph	2010-09-03T12:49:43Z					biological_process											owl:Class	
GO:0061215	biolink:NamedThing	mesonephric nephron development	The process whose specific outcome is the progression of a nephron in the mesonephros over time, from its formation to the mature structure. A nephron is the functional unit of the kidney.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-08-17T03:31:08Z					biological_process											owl:Class	
GO:0035314	biolink:NamedThing	scab formation	Formation of hardened covering (a scab) at a wound site. The scab has multiple functions including limiting blood loss, providing structural stability to the wound and guarding against infection.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0003063	biolink:NamedThing	negative regulation of heart rate by acetylcholine	The process in which acetylcholine released from vagus nerve endings binds to muscarinic receptors on the pacemaker cells and decreases the rate of heart muscle contraction.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of heart contraction rate by acetylcholine													biological_process											owl:Class	
GO:0003068	biolink:NamedThing	regulation of systemic arterial blood pressure by acetylcholine	The regulation of blood pressure mediated by acetylcholine signaling. Acetylcholine is an acetic acid ester of the organic base choline and functions as a neurotransmitter.	tmpzr1t_l9r_go_relaxed.owl	blood pressure regulation by acetylcholine													biological_process											owl:Class	
GO:0010075	biolink:NamedThing	regulation of meristem growth	Any process involved in maintaining the size and shape of a meristem.	tmpzr1t_l9r_go_relaxed.owl	regulation of meristem size													biological_process											owl:Class	
GO:0010073	biolink:NamedThing	meristem maintenance	Any process involved in maintaining the identity, size and shape of a meristem.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0051563	biolink:NamedThing	smooth endoplasmic reticulum calcium ion homeostasis	Any process involved in the maintenance of an internal steady state of calcium ions within the smooth endoplasmic reticulum of a cell or between the smooth endoplasmic reticulum and its surroundings.	tmpzr1t_l9r_go_relaxed.owl	calcium ion homeostasis in smooth ER|regulation of smooth ER calcium ion concentration|regulation of calcium ion concentration in smooth ER|smooth endoplasmic reticulum calcium ion concentration regulation|smooth ER calcium ion concentration regulation|regulation of smooth endoplasmic reticulum calcium ion concentration|regulation of calcium ion concentration in smooth endoplasmic reticulum|smooth ER calcium ion homeostasis|calcium ion homeostasis in smooth endoplasmic reticulum													biological_process											owl:Class	
GO:0005790	biolink:NamedThing	smooth endoplasmic reticulum	The smooth endoplasmic reticulum (smooth ER or SER) has no ribosomes attached to it. The smooth ER is the recipient of the proteins synthesized in the rough ER. Those proteins to be exported are passed to the Golgi complex, the resident proteins are returned to the rough ER and the lysosomal proteins after phosphorylation of their mannose residues are passed to the lysosomes. Glycosylation of the glycoproteins also continues. The smooth ER is the site of synthesis of lipids, including the phospholipids. The membranes of the smooth ER also contain enzymes that catalyze a series of reactions to detoxify both lipid-soluble drugs and harmful products of metabolism. Large quantities of certain compounds such as phenobarbital cause an increase in the amount of the smooth ER.	tmpzr1t_l9r_go_relaxed.owl	smooth ER|SER				Wikipedia:Endoplasmic_reticulum#Smooth_endoplasmic_reticulum|NIF_Subcellular:sao710427438									cellular_component											owl:Class	
GO:0061916	biolink:NamedThing	leading edge of axonal growth cone	That part of the axonal growth cone which represents the distal part of the structure.	tmpzr1t_l9r_go_relaxed.owl	distal tip of axonal growth cone|axonal growth cone leading edge							dph	2017-07-10T19:17:21Z					cellular_component											owl:Class	
GO:0090725	biolink:NamedThing	peripheral region of growth cone	The non-central region or periphery of the migrating motile tip of a growing nerve cell axon or dendrite.	tmpzr1t_l9r_go_relaxed.owl								tb	2016-11-18T12:44:25Z					cellular_component											owl:Class	
GO:0005818	biolink:NamedThing	aster	An array of microtubules emanating from a spindle pole MTOC that do not connect to kinetochores.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0005819	biolink:NamedThing	spindle	The array of microtubules and associated molecules that forms between opposite poles of a eukaryotic cell during mitosis or meiosis and serves to move the duplicated chromosomes apart.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Spindle_apparatus									cellular_component											owl:Class	
GO:0036497	biolink:NamedThing	eIF2alpha dephosphorylation in response to endoplasmic reticulum stress	The removal of a phosphate group from the translation initiation factor eIF2alpha, as a result of endoplasmic reticulum stress.	tmpzr1t_l9r_go_relaxed.owl	regulation of translation initiation by eIF2alpha dephosphorylation in response to endoplasmic reticulum stress|eIF2alpha dephosphorylation in response to ER stress							bf	2015-02-05T10:24:18Z					biological_process											owl:Class	
GO:0021587	biolink:NamedThing	cerebellum morphogenesis	The process in which the anatomical structure of the cerebellum is generated and organized. The cerebellum is the portion of the brain in the back of the head between the cerebrum and the pons. The cerebellum controls balance for walking and standing, modulates the force and range of movement and is involved in the learning of motor skills.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0021549	biolink:NamedThing	cerebellum development	The process whose specific outcome is the progression of the cerebellum over time, from its formation to the mature structure. The cerebellum is the portion of the brain in the back of the head between the cerebrum and the pons. In mice, the cerebellum controls balance for walking and standing, modulates the force and range of movement and is involved in the learning of motor skills.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0021922	biolink:NamedThing	Wnt signaling pathway involved in regulation of cell proliferation in dorsal spinal cord	The series of molecular signals initiated by binding of Wnt protein to a receptor on the surface of a cell in the dorsal spinal cord that affects the rate of its division.	tmpzr1t_l9r_go_relaxed.owl	Wnt receptor signaling pathway involved in regulation of cell proliferation in dorsal spinal cord|Wnt-activated signaling pathway involved in regulation of cell proliferation in dorsal spinal cord|Wnt receptor signalling pathway involved in regulation of cell proliferation in dorsal spinal cord													biological_process											owl:Class	
GO:0021921	biolink:NamedThing	regulation of cell proliferation in dorsal spinal cord	The process that modulates the frequency, rate or extent of cell proliferation in the dorsal spinal cord.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0033674	biolink:NamedThing	positive regulation of kinase activity	Any process that activates or increases the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of kinase activity|up regulation of kinase activity|kinase activator|upregulation of kinase activity|stimulation of kinase activity													biological_process											owl:Class	
GO:0098779	biolink:NamedThing	positive regulation of mitophagy in response to mitochondrial depolarization	Any process that activates or increases the frequency, rate or extent of mitophagy in response to mitochondrial depolarization.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of macromitophagy in response to mitochondrial depolarization													biological_process											owl:Class	
GO:0000423	biolink:NamedThing	mitophagy	The selective autophagy process in which a mitochondrion is degraded by macroautophagy.	tmpzr1t_l9r_go_relaxed.owl	macromitophagy					Note that this terms refers to the macroautophagy process and is named by common usage. Be aware that there are a separate micromitophagy and mitophagy by induced vacuole formation processes.								biological_process											owl:Class	
GO:0001828	biolink:NamedThing	inner cell mass cellular morphogenesis	The morphogenesis of cells in the inner cell mass.	tmpzr1t_l9r_go_relaxed.owl						See also the Anatomical Dictionary for Mouse Development ontology terms 'TS4, inner cell mass ; EMAP:14' and 'TS5, inner cell mass ; EMAP:24'.								biological_process											owl:Class	
GO:0001826	biolink:NamedThing	inner cell mass cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of an inner cell mass cell.	tmpzr1t_l9r_go_relaxed.owl						See also the Anatomical Dictionary for Mouse Development ontology terms 'TS4, inner cell mass ; EMAP:14'.								biological_process											owl:Class	
GO:0009034	biolink:NamedThing	tryptophanase activity	Catalysis of the reaction: L-tryptophan + H(2)O = indole + NH(4)(+) + pyruvate.	tmpzr1t_l9r_go_relaxed.owl	L-tryptophan indole-lyase activity|tryptophan catabolism, using tryptophanase|L-tryptophan indole-lyase (deaminating) activity|L-tryptophan indole-lyase (deaminating; pyruvate forming) activity|TNase activity|tryptophan catabolic process, using tryptophanase|L-tryptophanase activity				MetaCyc:TRYPDEG-PWY|KEGG_REACTION:R00673|MetaCyc:TRYPTOPHAN-RXN|RHEA:19553|EC:4.1.99.1|UniPathway:UPA00332	Note that this term has a MetaCyc pathway reference as the pathway only has a single step.								molecular_function											owl:Class	
GO:0006569	biolink:NamedThing	tryptophan catabolic process	The chemical reactions and pathways resulting in the breakdown of tryptophan, the chiral amino acid 2-amino-3-(1H-indol-3-yl)propanoic acid.	tmpzr1t_l9r_go_relaxed.owl	tryptophan catabolic process, using tryptophanase|tryptophan degradation|tryptophan catabolism|tryptophan catabolism, using tryptophanase|tryptophan breakdown													biological_process											owl:Class	
GO:0034257	biolink:NamedThing	nicotinamide riboside transmembrane transporter activity	Enables the transfer of nicotinamide riboside, which is a pyridine-3-carboxamide covalently bonded to a ribose sugar, from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl					RHEA:33163									molecular_function											owl:Class	
GO:0034258	biolink:NamedThing	nicotinamide riboside transport	The directed movement of a nicotinamide riboside, which is a pyridine-3-carboxamide covalently bonded to a ribose sugar, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0035034	biolink:NamedThing	histone acetyltransferase regulator activity	Binds to and modulates the activity of histone acetyltransferase.	tmpzr1t_l9r_go_relaxed.owl	histone acetylase regulator activity					See also the molecular function term 'histone acetyltransferase activity ; GO:0004402'.								molecular_function											owl:Class	
GO:0035035	biolink:NamedThing	histone acetyltransferase binding	Binding to an histone acetyltransferase.	tmpzr1t_l9r_go_relaxed.owl	histone acetylase binding													molecular_function											owl:Class	
GO:0010056	biolink:NamedThing	atrichoblast fate specification	The process involved in the specification of an atrichoblast.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0010055	biolink:NamedThing	atrichoblast differentiation	The process in which a relatively unspecialized cell acquires the specialized features of an atrichoblast, a root epidermal cell that will not give rise to a root hair.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0075186	biolink:NamedThing	negative regulation of infection cushion formation	Any process that stops, prevents, or reduces the frequency, rate or extent of symbiont infection cushion formation on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of infection cushion formation on or near host													biological_process											owl:Class	
GO:0075183	biolink:NamedThing	infection cushion formation	The process in which an organized mass of hyphae is formed and numerous infective hyphae develop from the hyphae mass.	tmpzr1t_l9r_go_relaxed.owl	infection cushion formation on or near host													biological_process											owl:Class	
GO:0014801	biolink:NamedThing	longitudinal sarcoplasmic reticulum	The portion of the free sarcoplasmic reticulum consisting of longitudinal tubules that connect terminal cisternae.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0016529	biolink:NamedThing	sarcoplasmic reticulum	A fine reticular network of membrane-limited elements that pervades the sarcoplasm of a muscle cell; continuous over large portions of the cell and with the nuclear envelope; that part of the endoplasmic reticulum specialized for calcium release, uptake and storage.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Endoplasmic_reticulum#Sarcoplasmic_reticulum	See also the cellular component terms 'sarcoplasm ; GO:0016528', 'nuclear envelope ; GO:0005635' and 'endoplasmic reticulum ; GO:0005783'.						GO:0008221		cellular_component											owl:Class	
GO:0001549	biolink:NamedThing	cumulus cell differentiation	The process in which a subpopulation of granulosa cells surrounding the oocyte acquires the specialized features of an ovarian cumulus cell.	tmpzr1t_l9r_go_relaxed.owl	ovarian cumulus cell differentiation													biological_process											owl:Class	
GO:0048165	biolink:NamedThing	fused antrum stage	The stage in oogenesis when the antral spaces fuse to form a single antral space. The oocyte is suspended in the cumulus oophorous and the first polar body in the perivitelline space.	tmpzr1t_l9r_go_relaxed.owl	mammalian oogenesis stage 8													biological_process											owl:Class	
GO:0048749	biolink:NamedThing	compound eye development	The process whose specific outcome is the progression of the compound eye over time, from its formation to the mature structure. The compound eye is an organ of sight that contains multiple repeating units, often arranged hexagonally. Each unit has its own lens and photoreceptor cell(s) and can generate either a single pixelated image or multiple images, per eye.	tmpzr1t_l9r_go_relaxed.owl	insect-type retina development											GO:0007456		biological_process											owl:Class	
GO:0005801	biolink:NamedThing	cis-Golgi network	The network of interconnected tubular and cisternal structures located at the convex side of the Golgi apparatus, which abuts the endoplasmic reticulum.	tmpzr1t_l9r_go_relaxed.owl	Golgi cis-face|cis Golgi network|cis face|Golgi cis face|forming face				NIF_Subcellular:sao632188024	The CGN is not considered part of the Golgi apparatus but is a separate organelle.								cellular_component											owl:Class	
GO:0005794	biolink:NamedThing	Golgi apparatus	A membrane-bound cytoplasmic organelle of the endomembrane system that further processes the core oligosaccharides (e.g. N-glycans) added to proteins in the endoplasmic reticulum and packages them into membrane-bound vesicles. The Golgi apparatus operates at the intersection of the secretory, lysosomal, and endocytic pathways.	tmpzr1t_l9r_go_relaxed.owl	Golgi ribbon|Golgi complex|Golgi				NIF_Subcellular:sao451912436|Wikipedia:Golgi_apparatus	Note that the Golgi apparatus can be located in various places in the cytoplasm. In plants and lower animal cells, the Golgi apparatus exists as many copies of discrete stacks dispersed throughout the cytoplasm, while the Golgi apparatus of interphase mammalian cells is a juxtanuclear, often pericentriolar reticulum, where the discrete Golgi stacks are stitched together to form a compact and interconnected ribbon, sometimes called the Golgi ribbon.								cellular_component											owl:Class	
GO:0032635	biolink:NamedThing	interleukin-6 production	The appearance of interleukin-6 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	tmpzr1t_l9r_go_relaxed.owl	IL-6 production|interleukin-6 secretion|interleukin-6 biosynthetic process											GO:0042226|GO:0072604		biological_process											owl:Class	
GO:0090073	biolink:NamedThing	positive regulation of protein homodimerization activity	Any process that increases the frequency, rate or extent of protein homodimerization, interacting selectively with an identical protein to form a homodimer.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-09-11T11:15:40Z					biological_process											owl:Class	
GO:0042803	biolink:NamedThing	protein homodimerization activity	Binding to an identical protein to form a homodimer.	tmpzr1t_l9r_go_relaxed.owl	dimerization activity													molecular_function											owl:Class	
GO:0020015	biolink:NamedThing	glycosome	A membrane-bounded organelle found in organisms from the order Kinetoplastida that houses the enzymes of glycolysis.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Glycosome									cellular_component											owl:Class	
GO:0060289	biolink:NamedThing	compartment boundary maintenance	A homeostatic process involved in the maintenance of a compartment boundary. A compartment boundary is a lineage restriction boundary within a developing tissue which does not correspond to some morphological barrier.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0007386	biolink:NamedThing	compartment pattern specification	The regionalization process in which embryonic segments are divided into compartments that will result in differences in cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	compartment specification													biological_process											owl:Class	
GO:1990176	biolink:NamedThing	MalFGK2 complex	Protein complex involved in maltose transport through the plasma membrane. In E. coli, the complex is a tetramer and consists of a cytoplasmic ATPase MalK homodimer together with a heterodimeric transmembrane subunit MalF-MalG.	tmpzr1t_l9r_go_relaxed.owl	MalFGK(2) complex|MalF-MalG-MalK-MalK complex|maltose transport complex, core subunit|maltose transport MalFGK2 complex|MalF-MalG-MalK(2) complex					The MalFGK2 complex lacks the maltose-binding subunit present in GO:1990060.		bhm	2013-08-30T11:10:14Z					cellular_component											owl:Class	
GO:1990060	biolink:NamedThing	maltose transport complex	Protein complex facilitating ATP-dependent maltose transport through inner cell membrane (periplasm to cytoplasm) in Gram-negative bacteria. In E. coli the system is composed of a periplasmic maltose-binding protein (MBP), two integral membrane proteins, MalF and MalG, and two copies of the cytoplasmic ATP-binding cassette MalK.	tmpzr1t_l9r_go_relaxed.owl	maltose ABC transporter complex|maltose ATP-binding cassette transporter complex							jl	2013-03-13T13:52:48Z					cellular_component											owl:Class	
GO:0070145	biolink:NamedThing	mitochondrial asparaginyl-tRNA aminoacylation	The process of coupling asparagine to asparaginyl-tRNA in a mitochondrion, catalyzed by asparaginyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0048451	biolink:NamedThing	petal formation	The process that gives rise to the petal. This process pertains to the initial formation of a structure from unspecified parts.	tmpzr1t_l9r_go_relaxed.owl												GO:0048419		biological_process											owl:Class	
GO:0048446	biolink:NamedThing	petal morphogenesis	The process in which the anatomical structures of the petal are generated and organized.	tmpzr1t_l9r_go_relaxed.owl												GO:0048418		biological_process											owl:Class	
GO:0008359	biolink:NamedThing	regulation of bicoid mRNA localization	Any process that modulates the frequency, rate or extent of the process in which bicoid mRNA is transported to, or maintained in, a specific location.	tmpzr1t_l9r_go_relaxed.owl	regulation of bicoid mRNA localisation													biological_process											owl:Class	
GO:0045450	biolink:NamedThing	bicoid mRNA localization	Any process in which bicoid mRNA is transported to and maintained within the oocyte as part of the specification of the anterior/posterior axis.	tmpzr1t_l9r_go_relaxed.owl	establishment and maintenance of bicoid mRNA localization|bicoid mRNA localisation													biological_process											owl:Class	
GO:0031347	biolink:NamedThing	regulation of defense response	Any process that modulates the frequency, rate or extent of a defense response.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0035580	biolink:NamedThing	specific granule lumen	The volume enclosed by the membrane of a specific granule, a granule with a membranous, tubular internal structure, found primarily in mature neutrophil cells. Most are released into the extracellular fluid. Specific granules contain lactoferrin, lysozyme, vitamin B12 binding protein and elastase.	tmpzr1t_l9r_go_relaxed.owl	secondary granule lumen							bf	2010-10-05T01:33:53Z					cellular_component											owl:Class	
GO:0042581	biolink:NamedThing	specific granule	Granule with a membranous, tubular internal structure, found primarily in mature neutrophil cells. Most are released into the extracellular fluid. Specific granules contain lactoferrin, lysozyme, vitamin B12 binding protein and elastase.	tmpzr1t_l9r_go_relaxed.owl	secondary granule				Wikipedia:Specific_granule									cellular_component											owl:Class	
GO:1902847	biolink:NamedThing	regulation of neuronal signal transduction	Any process that modulates the frequency, rate or extent of neuronal signal transduction.	tmpzr1t_l9r_go_relaxed.owl								sjp	2014-04-02T10:11:12Z					biological_process											owl:Class	
GO:0023041	biolink:NamedThing	neuronal signal transduction	The process in which an activated neuronal cell receptor conveys information down a signaling pathway, resulting in a change in the function or state of a cell. This process may be intracellular or intercellular.	tmpzr1t_l9r_go_relaxed.owl									2010-02-16T09:30:50Z					biological_process											owl:Class	
GO:0035937	biolink:NamedThing	estrogen secretion	The regulated release of estrogen into the circulatory system. Estrogen is a steroid hormone that stimulates or controls the development and maintenance of female sex characteristics in mammals.	tmpzr1t_l9r_go_relaxed.owl	oestrogen secretion							bf	2011-07-20T01:14:44Z					biological_process											owl:Class	
GO:1902606	biolink:NamedThing	regulation of large conductance calcium-activated potassium channel activity	Any process that modulates the frequency, rate or extent of large conductance calcium-activated potassium channel activity.	tmpzr1t_l9r_go_relaxed.owl	regulation of BK calcium-activated potassium channel activity|regulation of BK channel activity|regulation of BK KCa channels|regulation of large conductance KCa channels							sl	2014-01-02T18:51:03Z					biological_process											owl:Class	
GO:0060072	biolink:NamedThing	large conductance calcium-activated potassium channel activity	Enables the transmembrane transfer of potassium by a channel with a unit conductance of 100 to 220 picoSiemens that opens in response to stimulus by concerted actions of internal calcium ions and membrane potential. Large conductance calcium-activated potassium channels are less sensitive to calcium than are small or intermediate conductance calcium-activated potassium channels. Transport by a channel involves catalysis of facilitated diffusion of a solute (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel, without evidence for a carrier-mediated mechanism.	tmpzr1t_l9r_go_relaxed.owl	BK calcium-activated potassium channel activity|BK KCa channel activity|BK channel activity|large conductance KCa channel activity											GO:0022895		molecular_function											owl:Class	
GO:0061714	biolink:NamedThing	folic acid receptor activity	Combining selectively with extracellular folic acid and delivering it into the cell via endocytosis.	tmpzr1t_l9r_go_relaxed.owl	folate receptor activity							dph	2015-06-23T13:36:07Z					molecular_function											owl:Class	
GO:1900513	biolink:NamedThing	negative regulation of starch utilization system complex assembly	Any process that stops, prevents or reduces the frequency, rate or extent of starch utilization system complex assembly.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of starch utilization system complex assembly|downregulation of assembly of starch utilization system complex|down regulation of assembly of starch utilization system complex|down regulation of SUS complex assembly|inhibition of assembly of starch utilization system complex|down regulation of starch utilization system complex assembly|down-regulation of assembly of starch utilization system complex|inhibition of starch utilization system complex assembly|downregulation of SUS complex assembly|inhibition of SUS complex assembly|negative regulation of assembly of starch utilization system complex|down-regulation of SUS complex assembly|downregulation of starch utilization system complex assembly|negative regulation of SUS complex assembly							tt	2012-05-02T04:06:54Z					biological_process											owl:Class	
GO:0044574	biolink:NamedThing	starch utilization system complex assembly	The aggregation, arrangement and bonding together of the starch utilization system complex, a complex of cell envelope-associated proteins that degrades glycan.	tmpzr1t_l9r_go_relaxed.owl	SUS complex assembly|assembly of starch utilization system complex							jl	2012-04-19T03:40:24Z					biological_process											owl:Class	
GO:0072088	biolink:NamedThing	nephron epithelium morphogenesis	The process in which the anatomical structures of the nephron epithelium are generated and organized. The nephron epithelium is a tissue that covers the surface of a nephron.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-02-08T01:19:06Z					biological_process											owl:Class	
GO:0021983	biolink:NamedThing	pituitary gland development	The progression of the pituitary gland over time from its initial formation until its mature state. The pituitary gland is an endocrine gland that secretes hormones that regulate many other glands.	tmpzr1t_l9r_go_relaxed.owl	hypophysis development													biological_process											owl:Class	
GO:0035270	biolink:NamedThing	endocrine system development	Progression of the endocrine system over time, from its formation to a mature structure. The endocrine system is a system of hormones and ductless glands, where the glands release hormones directly into the blood, lymph or other intercellular fluid, and the hormones circulate within the body to affect distant organs. The major glands that make up the human endocrine system are the hypothalamus, pituitary, thyroid, parathryoids, adrenals, pineal body, and the reproductive glands which include the ovaries and testes.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0006921	biolink:NamedThing	cellular component disassembly involved in execution phase of apoptosis	The breakdown of structures such as organelles, proteins, or other macromolecular structures during apoptosis.	tmpzr1t_l9r_go_relaxed.owl	cellular component disassembly involved in apoptotic process|cellular component disassembly involved in apoptosis|disassembly of cell structures													biological_process											owl:Class	
GO:0097194	biolink:NamedThing	execution phase of apoptosis	A stage of the apoptotic process that starts with the controlled breakdown of the cell through the action of effector caspases or other effector molecules (e.g. cathepsins, calpains etc.). Key steps of the execution phase are rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died.	tmpzr1t_l9r_go_relaxed.owl	apoptosis|execution phase of apoptotic process							pr	2011-11-23T09:45:24Z					biological_process											owl:Class	
GO:0072178	biolink:NamedThing	nephric duct morphogenesis	The process in which the anatomical structures of the nephric duct are generated and organized. A nephric duct is a tube that drains a primitive kidney.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-02-26T02:35:29Z					biological_process											owl:Class	
GO:0072176	biolink:NamedThing	nephric duct development	The process whose specific outcome is the progression of a nephric duct over time, from its initial formation to a mature structure. A nephric duct is a tube that drains a primitive kidney.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-02-26T02:27:31Z					biological_process											owl:Class	
GO:0007140	biolink:NamedThing	male meiotic nuclear division	A cell cycle process by which the cell nucleus divides as part of a meiotic cell cycle in the male germline.	tmpzr1t_l9r_go_relaxed.owl	male meiosis|male nuclear division													biological_process											owl:Class	
GO:0002413	biolink:NamedThing	tolerance induction to tumor cell	A process of tolerance induction which leads to immunological tolerance of a tumor.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0060426	biolink:NamedThing	lung vasculature development	The biological process whose specific outcome is the progression of a lung vasculature from an initial condition to its mature state. This process begins with the formation of the lung vasculature and ends with the mature structure. The lung vasculature is composed of the tubule structures that carry blood or lymph in the lungs.	tmpzr1t_l9r_go_relaxed.owl	pulmonary vasculature development													biological_process											owl:Class	
GO:0030324	biolink:NamedThing	lung development	The process whose specific outcome is the progression of the lung over time, from its formation to the mature structure. In all air-breathing vertebrates the lungs are developed from the ventral wall of the oesophagus as a pouch which divides into two sacs. In amphibians and many reptiles the lungs retain very nearly this primitive sac-like character, but in the higher forms the connection with the esophagus becomes elongated into the windpipe and the inner walls of the sacs become more and more divided, until, in the mammals, the air spaces become minutely divided into tubes ending in small air cells, in the walls of which the blood circulates in a fine network of capillaries. In mammals the lungs are more or less divided into lobes, and each lung occupies a separate cavity in the thorax.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:2000186	biolink:NamedThing	negative regulation of phosphate transmembrane transport	Any process that stops, prevents, or reduces the frequency, rate or extent of phosphate transmembrane transport.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of phosphate membrane transport							vw	2010-10-15T11:33:08Z					biological_process											owl:Class	
GO:0035435	biolink:NamedThing	phosphate ion transmembrane transport	The process in which a phosphate is transported across a membrane.	tmpzr1t_l9r_go_relaxed.owl	phosphate ion membrane transport					Note that this term is not intended for use in annotating lateral movement within membranes.		bf	2010-04-08T11:24:06Z					biological_process											owl:Class	
GO:1902917	biolink:NamedThing	positive regulation of mating projection assembly	Any process that activates or increases the frequency, rate or extent of mating projection assembly.	tmpzr1t_l9r_go_relaxed.owl	up regulation of mating projection biogenesis|up-regulation of mating projection assembly|up regulation of mating projection assembly|positive regulation of mating projection biogenesis|upregulation of mating projection assembly|up-regulation of mating projection biogenesis|upregulation of mating projection biogenesis|activation of mating projection biogenesis|activation of mating projection assembly							di	2014-04-20T11:18:03Z					biological_process											owl:Class	
GO:1903354	biolink:NamedThing	regulation of distal tip cell migration	Any process that modulates the frequency, rate or extent of distal tip cell migration.	tmpzr1t_l9r_go_relaxed.owl								pr	2014-08-21T10:05:08Z					biological_process											owl:Class	
GO:1990201	biolink:NamedThing	alkanesulfonate monooxygenase complex	A protein complex capable of alkanesulfonate monooxygenase activity. Involved in the utilization of alkanesulfonates as sulfur sources under conditions of sulfate or cysteine starvation, catalyzing the conversion of alkanesulfonates into aldehydes and sulfite. In E.coli the complex consists of a SsuD tetramer.	tmpzr1t_l9r_go_relaxed.owl	SsuD complex							bhm	2013-10-03T14:55:08Z					cellular_component											owl:Class	
GO:0005829	biolink:NamedThing	cytosol	The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Cytosol|NIF_Subcellular:sao101633890									cellular_component											owl:Class	
GO:0048199	biolink:NamedThing	vesicle targeting, to, from or within Golgi	The process in which vesicles are directed to specific destination membranes during transport to, from or within the Golgi apparatus; mediated by the addition of specific coat proteins, including COPI and COPII proteins and clathrin, to the membrane during vesicle formation.	tmpzr1t_l9r_go_relaxed.owl	dictyosome vesicle targeting|Golgi vesicle targeting|vesicle targeting, to, from or within dictyosome													biological_process											owl:Class	
GO:0048193	biolink:NamedThing	Golgi vesicle transport	The directed movement of substances into, out of or within the Golgi apparatus, mediated by vesicles.	tmpzr1t_l9r_go_relaxed.owl	Golgi-derived vesicle transport													biological_process											owl:Class	
GO:0001873	biolink:NamedThing	polysaccharide immune receptor activity	Combining with a polysaccharide and transmitting the signal to initiate an innate immune response. A polysaccharide is a polymer of many (typically more than 10) monosaccharide residues linked glycosidically.	tmpzr1t_l9r_go_relaxed.owl	polysaccharide receptor activity													molecular_function											owl:Class	
GO:0097693	biolink:NamedThing	ocelloid	Eye-like subcellular structure found in dinoflagellates (a large group of single-celled eukaryotes). Consists of subcellular analogues to a cornea, lens, iris, and retina. Ocelloids are built from pre-existing organelles, including a cornea-like layer made of mitochondria and a retinal body made of anastomosing plastids.	tmpzr1t_l9r_go_relaxed.owl								pr	2015-11-13T14:27:01Z					cellular_component											owl:Class	
GO:0048702	biolink:NamedThing	embryonic neurocranium morphogenesis	The process in which the anatomical structures of the neurocranium are generated and organized during the embryonic phase. The neurocranium is the portion of the vertebrate skull surrounding the brain.	tmpzr1t_l9r_go_relaxed.owl	embryonic chondrocranium morphogenesis|embryonic braincase morphogenesis													biological_process											owl:Class	
GO:0048701	biolink:NamedThing	embryonic cranial skeleton morphogenesis	The process in which the anatomical structures of the cranial skeleton are generated and organized during the embryonic phase.	tmpzr1t_l9r_go_relaxed.owl	embryonic cranium morphogenesis													biological_process											owl:Class	
GO:1905365	biolink:NamedThing	regulation of intralumenal vesicle formation	Any process that modulates the frequency, rate or extent of intralumenal vesicle formation.	tmpzr1t_l9r_go_relaxed.owl	regulation of endosome membrane budding							bc	2016-08-16T12:00:01Z					biological_process											owl:Class	
GO:1904687	biolink:NamedThing	positive regulation of mitotic spindle disassembly	Any process that activates or increases the frequency, rate or extent of mitotic spindle disassembly.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of spindle degradation during mitosis|positive regulation of spindle breakdown during mitosis|positive regulation of mitotic spindle catabolism|up-regulation of mitotic spindle catabolism|up regulation of spindle breakdown during mitosis|upregulation of spindle degradation during mitosis|up-regulation of mitotic spindle disassembly|up-regulation of spindle breakdown during mitosis|positive regulation of spindle degradation during mitosis|activation of mitotic spindle disassembly|upregulation of mitotic spindle catabolism|up-regulation of mitotic spindle degradation|activation of spindle degradation during mitosis|upregulation of mitotic spindle degradation|up regulation of mitotic spindle breakdown|upregulation of spindle breakdown during mitosis|activation of mitotic spindle catabolism|up regulation of mitotic spindle disassembly|up-regulation of spindle disassembly during mitosis|upregulation of mitotic spindle breakdown|upregulation of mitotic spindle disassembly|positive regulation of spindle disassembly during mitosis|upregulation of spindle disassembly during mitosis|positive regulation of mitotic spindle degradation|up regulation of spindle disassembly during mitosis|up regulation of spindle degradation during mitosis|activation of mitotic spindle breakdown|up-regulation of mitotic spindle breakdown|activation of spindle disassembly during mitosis|activation of mitotic spindle degradation|up regulation of mitotic spindle degradation|up regulation of mitotic spindle catabolism|positive regulation of mitotic spindle breakdown|activation of spindle breakdown during mitosis							al	2015-09-24T14:20:13Z					biological_process											owl:Class	
GO:0051228	biolink:NamedThing	mitotic spindle disassembly	The controlled breakdown of the spindle during a mitotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl	spindle disassembly during mitosis|mitotic spindle catabolism|spindle breakdown during mitosis|mitotic spindle breakdown|mitotic spindle degradation|spindle degradation during mitosis													biological_process											owl:Class	
GO:0010731	biolink:NamedThing	protein glutathionylation	The protein modification process in which a glutathione molecule is added to a protein amino acid through a disulfide linkage.	tmpzr1t_l9r_go_relaxed.owl	protein amino acid glutathionylation													biological_process											owl:Class	
GO:0002158	biolink:NamedThing	osteoclast proliferation	The multiplication or reproduction of osteoclasts, resulting in the expansion of an osteoclast cell population. An osteoclast is a specialized phagocytic cell associated with the absorption and removal of the mineralized matrix of bone tissue, which typically differentiates from monocytes.	tmpzr1t_l9r_go_relaxed.owl								hjd	2010-02-03T01:50:37Z					biological_process											owl:Class	
GO:0061079	biolink:NamedThing	left horn of sinus venosus development	The progression of the left horn of the sinus venosus from its initial formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-04-08T02:40:27Z					biological_process											owl:Class	
GO:0003235	biolink:NamedThing	sinus venosus development	The progression of the sinus venosus over time, from its formation to the mature structure. The sinus venosus is a heart chamber attached to the atrium on the venous side of the embryonic heart.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-10-13T11:12:34Z					biological_process											owl:Class	
GO:0071892	biolink:NamedThing	thrombocyte activation	A cell activation process that occurs in thrombocytes and consists of a series of progressive, overlapping events including shape change, adhesiveness, and aggregation, which, when carried through to completion, lead to the formation of a stable hemostatic plug. Thrombocytes are nucleated cells found in non-mammalian vertebrates and are involved in hemostasis. They are the functional equivalent of the non-nucleated platelets found in mammals.	tmpzr1t_l9r_go_relaxed.owl	blood coagulation, thrombocyte activation							mah	2010-09-14T03:06:33Z					biological_process											owl:Class	
GO:0007596	biolink:NamedThing	blood coagulation	The sequential process in which the multiple coagulation factors of the blood interact, ultimately resulting in the formation of an insoluble fibrin clot; it may be divided into three stages: stage 1, the formation of intrinsic and extrinsic prothrombin converting principle; stage 2, the formation of thrombin; stage 3, the formation of stable fibrin polymers.	tmpzr1t_l9r_go_relaxed.owl	blood clotting				Wikipedia:Coagulation									biological_process											owl:Class	
GO:0075290	biolink:NamedThing	regulation of aplanospore formation	Any process that modulates the frequency, rate or extent of aplanospore formation, a process in which a nonmotile, asexual spore is formed within a cell in certain algae and fungi (commonly in the Phycomycetes), the wall of aplanospore is distinct from that of the parent cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0098535	biolink:NamedThing	de novo centriole assembly involved in multi-ciliated epithelial cell differentiation	Centriole assembly in which a centriole arises de novo by a process involving an electron-dense structure known as a deuterosome, rather than by duplication of an existing centriole, and occurring as part of multi-ciliated epithelial cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	deuterosome pathway|multiciliogenesis|de novo centriole assembly via deuterosome|deuterosomal basal body biogenesis|centriole amplification|deuterosome-mediated centriole biogenesis|multiciliation|de novo centriole assembly					In most eukaryotic cells, 'centriole' (GO:0005814) and 'ciliary basal body' (GO:0036064) represent a common entity that cycles through its function in cell division, then ciliogenesis, then cell division again. However, these structures are modified extensively as they transition into each other, and may contain different proteins, specific to each component.		dos	2013-10-22T16:03:13Z					biological_process											owl:Class	
GO:1903251	biolink:NamedThing	multi-ciliated epithelial cell differentiation	The process in which a relatively unspecialized cell acquires the specialized features of a multi-ciliated epithelial cell.	tmpzr1t_l9r_go_relaxed.owl	multiciliate cell differentiation							tb	2014-08-05T19:21:21Z					biological_process											owl:Class	
GO:0031051	biolink:NamedThing	scnRNA processing	Cleavage of noncoding, double-stranded RNAs transcribed from the micronuclear genome to produce scnRNAs, small RNAs (~28 nucleotides) that direct the deletion of micronuclear-limited sequences from the developing macronuclear genome.	tmpzr1t_l9r_go_relaxed.owl	scnRNA production													biological_process											owl:Class	
GO:0031049	biolink:NamedThing	programmed DNA elimination	The DNA metabolic process in which micronuclear-limited sequences, internal eliminated sequences (IES) and breakage eliminated sequences (BES) are removed from the developing macronucleus (anlage) of a ciliate.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0099123	biolink:NamedThing	somato-dendritic dopamine secretion	The regulated release of dopamine from the somatodendritic compartment (cell body or dendrites) of a neuron.	tmpzr1t_l9r_go_relaxed.owl	STD DA release|STD dopamine release|somatodendritic dopamine release													biological_process											owl:Class	
GO:0036477	biolink:NamedThing	somatodendritic compartment	The region of a neuron that includes the cell body (cell soma) and dendrite(s), but excludes the axon.	tmpzr1t_l9r_go_relaxed.owl								bf	2014-07-24T10:06:19Z					cellular_component											owl:Class	
GO:0045697	biolink:NamedThing	regulation of synergid differentiation	Any process that modulates the frequency, rate or extent of synergid cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	regulation of synergid cell differentiation													biological_process											owl:Class	
GO:0009563	biolink:NamedThing	synergid differentiation	The process in which an uncellularized nucleus cellularizes and acquires the specialized features of a synergid cell.	tmpzr1t_l9r_go_relaxed.owl	synergid cell differentiation													biological_process											owl:Class	
GO:0070733	biolink:NamedThing	protein adenylyltransferase activity	Catalysis of the reaction: ATP + protein = diphosphate + adenylyl-protein; mediates the addition of an adenylyl (adenosine 5'-monophosphate; AMP group) to specific residues of target proteins.	tmpzr1t_l9r_go_relaxed.owl	adenosine monophosphate-protein transferase activity|AMPylator				EC:2.7.7.n1			mah	2009-06-18T01:09:15Z					molecular_function											owl:Class	
GO:0015658	biolink:NamedThing	branched-chain amino acid transmembrane transporter activity	Enables the transfer of branched-chain amino acids from one side of a membrane to the other. Branched-chain amino acids are amino acids with a branched carbon skeleton without rings.	tmpzr1t_l9r_go_relaxed.owl	branched-chain aliphatic amino acid transmembrane transporter activity|branched-chain aliphatic amino acid transporter activity|leucine/valine/isoleucine permease activity|valine/tyrosine/tryptophan permease activity				Reactome:R-HSA-9672770							GO:1901240		molecular_function											owl:Class	
GO:0015803	biolink:NamedThing	branched-chain amino acid transport	The directed movement of branched-chain amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Branched-chain amino acids are amino acids with a branched carbon skeleton without rings.	tmpzr1t_l9r_go_relaxed.owl	branched-chain amino-acid anion transport|branched-chain amino-acid anions transport|branched-chain aliphatic amino acid transport											GO:1900755		biological_process											owl:Class	
GO:0014069	biolink:NamedThing	postsynaptic density	An electron dense network of proteins within and adjacent to the postsynaptic membrane of an asymmetric, neuron-neuron synapse. Its major components include neurotransmitter receptors and the proteins that spatially and functionally organize them such as anchoring and scaffolding molecules, signaling enzymes and cytoskeletal components.	tmpzr1t_l9r_go_relaxed.owl	neuronal postsynaptic density|post-synaptic density|post synaptic density|postsynaptic density of dendrite				Wikipedia:Postsynaptic_density|NIF_Subcellular:sao1196688972			pr	2013-07-02T09:44:28Z			GO:0097481|GO:0097483		cellular_component											owl:Class	
GO:0031241	biolink:NamedThing	periplasmic side of cell outer membrane	The side (leaflet) of the outer membrane that faces the periplasm of the cell.	tmpzr1t_l9r_go_relaxed.owl	internal side of outer membrane|internal leaflet of cell outer membrane|internal side of cell outer membrane					In GO, 'internal side' still refers to part of the membrane and does not refer to components beyond (inside of) the membrane.								cellular_component											owl:Class	
GO:1903438	biolink:NamedThing	positive regulation of mitotic cytokinetic process	Any process that activates or increases the frequency, rate or extent of mitotic cytokinetic process.	tmpzr1t_l9r_go_relaxed.owl	activation of mitotic cytokinetic process|upregulation of mitotic cytokinetic process|up-regulation of mitotic cytokinetic process|up regulation of mitotic cytokinetic process							tb	2014-09-15T23:11:55Z					biological_process											owl:Class	
GO:0070971	biolink:NamedThing	endoplasmic reticulum exit site	An endoplasmic reticulum part at which COPII-coated vesicles are produced.	tmpzr1t_l9r_go_relaxed.owl	ER exit site|transitional ER				NIF_Subcellular:sao124393998			mah	2009-10-02T12:19:23Z					cellular_component											owl:Class	
GO:0039007	biolink:NamedThing	pronephric nephron morphogenesis	The process in which the anatomical structures of the pronephric nephron are generated and organized. A pronephric nephron is the functional unit of the pronephros.	tmpzr1t_l9r_go_relaxed.owl								bf	2010-07-02T09:38:53Z					biological_process											owl:Class	
GO:0039019	biolink:NamedThing	pronephric nephron development	The process whose specific outcome is the progression of the pronephric nephron over time, from its formation to the mature structure. A pronephric nephron is the functional unit of the pronephros.	tmpzr1t_l9r_go_relaxed.owl								bf	2010-07-02T10:10:20Z					biological_process											owl:Class	
GO:2000675	biolink:NamedThing	negative regulation of type B pancreatic cell apoptotic process	Any process that stops, prevents or reduces the frequency, rate or extent of type B pancreatic cell apoptotic process.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of pancreatic beta cell apoptosis|negative regulation of type B pancreatic cell apoptosis|negative regulation of pancreatic B cell apoptosis							pr	2011-05-09T11:51:12Z					biological_process											owl:Class	
GO:0097050	biolink:NamedThing	type B pancreatic cell apoptotic process	Any apoptotic process in a type B pancreatic cell, a cell located towards center of the islets of Langerhans that secretes insulin.	tmpzr1t_l9r_go_relaxed.owl	pancreatic B cell apoptosis|type B pancreatic cell apoptosis|pancreatic beta cell apoptosis							pr	2011-05-04T02:24:38Z					biological_process											owl:Class	
GO:0030217	biolink:NamedThing	T cell differentiation	The process in which a precursor cell type acquires characteristics of a more mature T-cell. A T cell is a type of lymphocyte whose definin characteristic is the expression of a T cell receptor complex.	tmpzr1t_l9r_go_relaxed.owl	T-lymphocyte differentiation|T lymphocyte differentiation|T cell development|T-cell differentiation					Note that the term 'thymocyte differentiation' was merged into this term because thymocytes are T cells, and thus the term was essentially redundant. Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.						GO:0046652|GO:0042112		biological_process											owl:Class	
GO:0048660	biolink:NamedThing	regulation of smooth muscle cell proliferation	Any process that modulates the frequency, rate or extent of smooth muscle cell proliferation.	tmpzr1t_l9r_go_relaxed.owl	regulation of SMC proliferation													biological_process											owl:Class	
GO:0048659	biolink:NamedThing	smooth muscle cell proliferation	The multiplication or reproduction of smooth muscle cells, resulting in the expansion of a cell population.	tmpzr1t_l9r_go_relaxed.owl	SMC proliferation													biological_process											owl:Class	
GO:0032915	biolink:NamedThing	positive regulation of transforming growth factor beta2 production	Any process that activates or increases the frequency, rate, or extent of production of transforming growth factor-beta2.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of transforming growth factor-beta2 production|up regulation of transforming growth factor-beta2 production|positive regulation of TGFB2 production|upregulation of transforming growth factor-beta2 production|stimulation of transforming growth factor-beta2 production|up-regulation of transforming growth factor-beta2 production|positive regulation of TGF-B2 production|activation of transforming growth factor-beta2 production													biological_process											owl:Class	
GO:0032906	biolink:NamedThing	transforming growth factor beta2 production	The appearance of transforming growth factor-beta2 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	tmpzr1t_l9r_go_relaxed.owl	TGFB2 production|TGF-B2 production|transforming growth factor-beta2 production													biological_process											owl:Class	
GO:0090242	biolink:NamedThing	retinoic acid receptor signaling pathway involved in somitogenesis	The series of molecular signals generated as a consequence of a retinoic acid receptor binding to one of its physiological ligands that contributes to somitogenesis.	tmpzr1t_l9r_go_relaxed.owl	retinoic acid receptor signalling pathway involved in somitogenesis							tb	2010-01-22T10:42:54Z					biological_process											owl:Class	
GO:0001756	biolink:NamedThing	somitogenesis	The formation of mesodermal clusters that are arranged segmentally along the anterior posterior axis of an embryo.	tmpzr1t_l9r_go_relaxed.owl	formation of mesodermal clusters				Wikipedia:Somitogenesis									biological_process											owl:Class	
GO:0072218	biolink:NamedThing	metanephric ascending thin limb development	The process whose specific outcome is the progression of a metanephric ascending thin limb over time, from its formation to the mature structure. The metanephric ascending thin limb is a segment of a nephron tubule in the metanephros lying in the inner medulla that is permeable to ions but not to water and has a simple epithelium; active transepithelial solute transport is absent.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-03-18T03:34:42Z					biological_process											owl:Class	
GO:0072236	biolink:NamedThing	metanephric loop of Henle development	The process whose specific outcome is the progression of the metanephric loop of Henle over time, from its formation to the mature structure. The metanephric loop of Henle is a metanephric nephron tubule that connects the proximal convoluted tubule to the distal convoluted tubule in the metanephros.	tmpzr1t_l9r_go_relaxed.owl	metanephric intermediate tubule development							mah	2010-03-18T03:46:18Z					biological_process											owl:Class	
GO:0036286	biolink:NamedThing	eisosome filament	A filamentous cortical structure formed, in S. pombe, by the eisosome component Pil1.	tmpzr1t_l9r_go_relaxed.owl	linear eisosome							bf	2012-07-16T10:52:24Z					cellular_component											owl:Class	
GO:0032126	biolink:NamedThing	eisosome	A cell part that is composed of the eisosome membrane or MCC domain, a furrow-like plasma membrane sub-domain and associated integral transmembrane proteins, and the proteins (eisosome filaments) that form a scaffolding lattice on the cytoplasmic face. Eisosomes broadly affect overall plasma membrane organization.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Eisosome									cellular_component											owl:Class	
GO:0106020	biolink:NamedThing	regulation of vesicle docking	Any process that modulates the frequency, rate or extent of vesicle docking.	tmpzr1t_l9r_go_relaxed.owl	regulation of vesicle to membrane docking							hjd	2017-05-16T13:58:54Z					biological_process											owl:Class	
GO:0000712	biolink:NamedThing	resolution of meiotic recombination intermediates	The cleavage and rejoining of intermediates, such as Holliday junctions, formed during meiotic recombination to produce two intact molecules in which genetic material has been exchanged.	tmpzr1t_l9r_go_relaxed.owl	resolution of meiotic joint molecules as recombinants													biological_process											owl:Class	
GO:0021900	biolink:NamedThing	ventricular zone cell fate commitment	The commitment of neuroblast to become a basal progenitor cell. Basal progenitor cells are neuronal precursor cells that are committed to becoming neurons.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0021863	biolink:NamedThing	forebrain neuroblast differentiation	The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of basal progenitor cells, neuroblasts that lose their contacts with the ventricular surface. Differentiation includes the processes involved in commitment of a cell to a specific fate.	tmpzr1t_l9r_go_relaxed.owl	abventricular progenitor cell differentiation|non-surface dividing progenitor cell differentiation|intermediate progenitor cell differentiation													biological_process											owl:Class	
GO:0097562	biolink:NamedThing	left lateral basal body pair	Set of two basal bodies found in Giardia species (trophozoite stage). It comprises the anterior and ventral basal bodies located to the right of the left nucleus of the trophozoite when viewed dorsally.	tmpzr1t_l9r_go_relaxed.owl						Due to the asymmetric nature of the Giardia trophozoite, this term is defined spatially as the trophozoite is viewed from the dorsal side, with the two nuclei dorsal to the ventral disc, and the ventral disc toward the anterior.		pr	2014-02-05T16:09:11Z					cellular_component											owl:Class	
GO:0042995	biolink:NamedThing	cell projection	A prolongation or process extending from a cell, e.g. a flagellum or axon.	tmpzr1t_l9r_go_relaxed.owl	cellular process|cellular projection|cell process													cellular_component											owl:Class	
GO:0034080	biolink:NamedThing	CENP-A containing chromatin assembly	The formation of chromatin containing the histone H3 variant CENP-A to form centromeric chromatin. This specialised chromatin occurs at centromeric region in point centromeres,  and the central core in modular centromeres.	tmpzr1t_l9r_go_relaxed.owl	DNA replication-independent nucleosome assembly at centromere|CenH3-containing nucleosome assembly at centromere|centromere specific nucleosome exchange|centromeric DNA replication-independent nucleosome assembly|CENP-A deposition|CENP-A loading|CENP-A containing nucleosome assembly at centromere|centromere-specific histone exchange|CENP-A containing nucleosome assembly	https://github.com/geneontology/go-ontology/issues/22130										GO:0034509		biological_process											owl:Class	
GO:0009573	biolink:NamedThing	chloroplast ribulose bisphosphate carboxylase complex	A complex, located in the chloroplast, containing either both large and small subunits or just small subunits which carries out the activity of producing 3-phosphoglycerate from carbon dioxide and ribulose-1,5-bisphosphate. An example of this component is found in Arabidopsis thaliana.	tmpzr1t_l9r_go_relaxed.owl	chloroplast RubisCO complex													cellular_component											owl:Class	
GO:0009507	biolink:NamedThing	chloroplast	A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Chloroplast									cellular_component											owl:Class	
GO:0021536	biolink:NamedThing	diencephalon development	The process whose specific outcome is the progression of the diencephalon over time, from its formation to the mature structure. The diencephalon is the paired caudal parts of the prosencephalon from which the thalamus, hypothalamus, epithalamus and subthalamus are derived; these regions regulate autonomic, visceral and endocrine function, and process information directed to the cerebral cortex.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0042175	biolink:NamedThing	nuclear outer membrane-endoplasmic reticulum membrane network	The continuous network of membranes encompassing the nuclear outer membrane and the endoplasmic reticulum membrane.	tmpzr1t_l9r_go_relaxed.owl	NE-ER continuum|nuclear envelope-endoplasmic reticulum network|nuclear envelope-endoplasmic reticulum continuum|nuclear membrane-endoplasmic reticulum continuum|nuclear membrane-ER network|nuclear envelope-ER network|NE-ER network													cellular_component											owl:Class	
GO:0012505	biolink:NamedThing	endomembrane system	A collection of membranous structures involved in transport within the cell. The main components of the endomembrane system are endoplasmic reticulum, Golgi bodies, vesicles, cell membrane and nuclear envelope. Members of the endomembrane system pass materials through each other or though the use of vesicles.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Endomembrane_system									cellular_component											owl:Class	
GO:0014034	biolink:NamedThing	neural crest cell fate commitment	The process in which a cell becomes committed to become a neural crest cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0014029	biolink:NamedThing	neural crest formation	The formation of the specialized region of ectoderm between the neural ectoderm (neural plate) and non-neural ectoderm. The neural crest gives rise to the neural crest cells that migrate away from this region as neural tube formation procedes.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0060466	biolink:NamedThing	activation of meiosis involved in egg activation	Any process that starts the inactive process of meiosis in an egg after the egg has been fertilized or physiologically activated. Eggs generally arrest in meiosis and complete the process after activation.	tmpzr1t_l9r_go_relaxed.owl	reactivation of meiosis after fertilization|resumption of meiosis involved in egg activation													biological_process											owl:Class	
GO:0007343	biolink:NamedThing	egg activation	The process in which the egg becomes metabolically active, initiates protein and DNA synthesis and undergoes structural changes to its cortex and/or cytoplasm.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Egg_activation									biological_process											owl:Class	
GO:0045951	biolink:NamedThing	positive regulation of mitotic recombination	Any process that activates or increases the frequency, rate or extent of DNA recombination during mitosis.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of mitotic recombination|activation of mitotic recombination|up regulation of mitotic recombination|stimulation of mitotic recombination|upregulation of mitotic recombination|positive regulation of recombination within rDNA repeats													biological_process											owl:Class	
GO:0031951	biolink:NamedThing	positive regulation of glucocorticoid catabolic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glucocorticoids.	tmpzr1t_l9r_go_relaxed.owl	upregulation of glucocorticoid catabolic process|activation of glucocorticoid catabolic process|stimulation of glucocorticoid catabolic process|up regulation of glucocorticoid catabolic process|up-regulation of glucocorticoid catabolic process													biological_process											owl:Class	
GO:0006713	biolink:NamedThing	glucocorticoid catabolic process	The chemical reactions and pathways resulting in the breakdown of glucocorticoids, hormonal C21 corticosteroids synthesized from cholesterol.	tmpzr1t_l9r_go_relaxed.owl	glucocorticoid catabolism|glucocorticoid degradation|glucocorticoid breakdown													biological_process											owl:Class	
GO:0010891	biolink:NamedThing	negative regulation of sequestering of triglyceride	Any process that decreases the rate, frequency or extent of sequestering of triglyceride. Triglyceride sequestration is the process of binding or confining any triester of glycerol such that it is separated from other components of a biological system.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of sequestering of triacylglycerol|negative regulation of triglyceride sequestration													biological_process											owl:Class	
GO:0030730	biolink:NamedThing	sequestering of triglyceride	The process of binding or confining any triester of glycerol such that it is separated from other components of a biological system.	tmpzr1t_l9r_go_relaxed.owl	triglyceride sequestration|sequestration of triacylglycerol|retention of triacylglycerol|triglyceride sequestering|storage of triglyceride|retention of triglyceride|sequestration of triglyceride|sequestering of triacylglycerol|triglyceride retention|triacylglycerol retention|triglyceride storage|triacylglycerol sequestering|triacylglycerol storage|triacylglycerol sequestration|storage of triacylglycerol													biological_process											owl:Class	
GO:0000221	biolink:NamedThing	vacuolar proton-transporting V-type ATPase, V1 domain	The V1 domain of a proton-transporting V-type ATPase found in the vacuolar membrane.	tmpzr1t_l9r_go_relaxed.owl	vacuolar hydrogen ion-transporting ATPase V1 domain					Note that this domain generally consists of eight subunits.								cellular_component											owl:Class	
GO:1902100	biolink:NamedThing	negative regulation of metaphase/anaphase transition of cell cycle	Any process that stops, prevents or reduces the frequency, rate or extent of metaphase/anaphase transition of cell cycle.	tmpzr1t_l9r_go_relaxed.owl	inhibition of metaphase/anaphase transition of cell cycle|down-regulation of metaphase/anaphase transition of cell cycle|down regulation of metaphase/anaphase transition of cell cycle|downregulation of metaphase/anaphase transition of cell cycle							jl	2013-05-02T12:45:20Z					biological_process											owl:Class	
GO:0044784	biolink:NamedThing	metaphase/anaphase transition of cell cycle	The cell cycle process in which a cell progresses from metaphase to anaphase as part of the cell cycle.	tmpzr1t_l9r_go_relaxed.owl								jl	2013-05-02T13:09:34Z					biological_process											owl:Class	
GO:0048441	biolink:NamedThing	petal development	The process whose specific outcome is the progression of the petal over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl												GO:0048417		biological_process											owl:Class	
GO:0048465	biolink:NamedThing	corolla development	The process whose specific outcome is the progression of the corolla over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0031230	biolink:NamedThing	intrinsic component of cell outer membrane	The component of the cell outer membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.	tmpzr1t_l9r_go_relaxed.owl	intrinsic to cell outer membrane													cellular_component											owl:Class	
GO:0009279	biolink:NamedThing	cell outer membrane	A lipid bilayer that forms the outermost membrane of the cell envelope; enriched in polysaccharide and protein; the outer leaflet of the membrane contains specific lipopolysaccharide structures.	tmpzr1t_l9r_go_relaxed.owl	outer membrane of cell					To annotate the plasma (cytoplasmic) membrane, see instead GO:0005886.								cellular_component											owl:Class	
GO:0090661	biolink:NamedThing	box H/ACA telomerase RNP complex	A box H/ACA ribonucleoprotein complex that contains the RNA component of vertebrate telomerase, the enzyme essential for the replication of chromosome termini in most eukaryotes. This ribonucleoprotein complex is a structural box H/ACA RNP, which does not have the catalytic pseudouridylation function shared by the majority of H/ACA RNPs present in the cell.	tmpzr1t_l9r_go_relaxed.owl								tb	2015-09-21T14:46:16Z					cellular_component											owl:Class	
GO:0005697	biolink:NamedThing	telomerase holoenzyme complex	Telomerase is a ribonucleoprotein enzyme complex, with a minimal catalytic core composed of a catalytic reverse transcriptase subunit and an RNA subunit that provides the template for telomeric DNA addition. In vivo, the holoenzyme complex often contains additional subunits.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0038030	biolink:NamedThing	non-canonical Wnt signaling pathway via MAPK cascade	The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, where the signal is passed on via the MAPKKK cascade.	tmpzr1t_l9r_go_relaxed.owl	non-canonical Wnt receptor signaling pathway via MAPKKK cascade|non-canonical Wnt receptor signalling pathway via MAPKKK cascade|non-canonical Wnt-activated signaling pathway via MAPK cascade|non-canonical Wnt receptor signaling pathway via MAPK cascade|non-canonical Wnt receptor signaling pathway via MAPK signaling							bf	2011-09-08T01:46:07Z					biological_process											owl:Class	
GO:1903573	biolink:NamedThing	negative regulation of response to endoplasmic reticulum stress	Any process that stops, prevents or reduces the frequency, rate or extent of a response to endoplasmic reticulum stress.	tmpzr1t_l9r_go_relaxed.owl	downregulation of ER stress response|down regulation of response to ER stress|negative regulation of cellular response to endoplasmic reticulum stress|negative regulation of ER stress response|negative regulation of response to ER stress|down regulation of response to endoplasmic reticulum stress|down regulation of cellular response to endoplasmic reticulum stress|inhibition of response to endoplasmic reticulum stress|downregulation of response to ER stress|inhibition of ER stress response|down-regulation of response to endoplasmic reticulum stress|inhibition of cellular response to endoplasmic reticulum stress|downregulation of response to endoplasmic reticulum stress|down regulation of ER stress response|inhibition of response to ER stress|down-regulation of ER stress response|down-regulation of response to ER stress|down-regulation of cellular response to endoplasmic reticulum stress|downregulation of cellular response to endoplasmic reticulum stress							bf	2014-10-27T16:15:30Z					biological_process											owl:Class	
GO:0034976	biolink:NamedThing	response to endoplasmic reticulum stress	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stress acting at the endoplasmic reticulum. ER stress usually results from the accumulation of unfolded or misfolded proteins in the ER lumen.	tmpzr1t_l9r_go_relaxed.owl	response to ER stress|cellular response to endoplasmic reticulum stress|ER stress response													biological_process											owl:Class	
GO:0034340	biolink:NamedThing	response to type I interferon	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a type I interferon stimulus. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families.	tmpzr1t_l9r_go_relaxed.owl	response to type I IFN													biological_process											owl:Class	
GO:0090398	biolink:NamedThing	cellular senescence	A cell aging process stimulated in response to cellular stress, whereby normal cells lose the ability to divide through irreversible cell cycle arrest.	tmpzr1t_l9r_go_relaxed.owl								tb	2011-01-05T02:27:08Z					biological_process											owl:Class	
GO:0035514	biolink:NamedThing	DNA demethylase activity	Catalysis of the removal of a methyl group from one or more nucleosides within a DNA molecule.	tmpzr1t_l9r_go_relaxed.owl								bf	2010-04-30T02:36:43Z					molecular_function											owl:Class	
GO:0060175	biolink:NamedThing	brain-derived neurotrophic factor-activated receptor activity	Combining with a brain-derived neurotrophic factor and transmitting the signal across the plasma membrane to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	brain-derived neurotrophic factor receptor activity|BDNF receptor activity|BDNF-activated receptor activity					Note that this term represents an activity and not a gene product, and should only be used when the receptor binds the ligand BDNF. For receptors that bind other growth factors, consider annotating to other terms under 'transmembrane signaling receptor activity ; GO:0004888.								molecular_function											owl:Class	
GO:0031547	biolink:NamedThing	brain-derived neurotrophic factor receptor signaling pathway	The series of molecular signals generated as a consequence of a brain-derived neurotrophic factor receptor binding to one of its physiological ligands.	tmpzr1t_l9r_go_relaxed.owl	BDNF signalling pathway|BDNF receptor signaling pathway|brain-derived neurotrophic factor receptor signalling pathway													biological_process											owl:Class	
GO:0090229	biolink:NamedThing	negative regulation of red or far-red light signaling pathway	Any process that decreases the rate, frequency or extent of the red or far-red signaling pathway, the series of molecular signals initiated upon sensing by photoreceptor molecules of red light or far red light.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of red or far-red light signalling pathway|negative regulation of phytochrome signaling pathway							tb	2010-01-19T04:03:29Z					biological_process											owl:Class	
GO:0010017	biolink:NamedThing	red or far-red light signaling pathway	The series of molecular signals initiated upon sensing by photoreceptor molecules of red light or far red light. Red light is electromagnetic radiation of wavelength of 580-700nm. Far red light is electromagnetic radiation of wavelength 700-800nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reversed by exposure to far red light. During the initial phase the phytochrome molecule is only present in the red light absorbing form, but on absorption of red light it changes to a far red light absorbing form, triggering progress through development. An immediate short period of exposure to far red light entirely returns the pigment to its initial state and prevents triggering of the developmental process. A thirty minute break between red and subsequent far red light exposure renders the red light effect irreversible, and development then occurs regardless of whether far red light exposure subsequently occurs.	tmpzr1t_l9r_go_relaxed.owl	red/far red light signaling pathway|phytochrome signaling pathway|red or far-red light signalling pathway|red or far-red light signal transduction|red or far red light signaling pathway													biological_process											owl:Class	
GO:0001556	biolink:NamedThing	oocyte maturation	A developmental process, independent of morphogenetic (shape) change, that is required for an oocyte to attain its fully functional state. Oocyte maturation commences after reinitiation of meiosis commonly starting with germinal vesicle breakdown, and continues up to the second meiotic arrest prior to fertilization.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Oocyte_maturation									biological_process											owl:Class	
GO:0042651	biolink:NamedThing	thylakoid membrane	The pigmented membrane of any thylakoid.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0033081	biolink:NamedThing	regulation of T cell differentiation in thymus	Any process that modulates the frequency, rate or extent of T cell differentiation in the thymus.	tmpzr1t_l9r_go_relaxed.owl	regulation of T cell development in thymus|regulation of thymocyte differentiation|regulation of thymocyte cell differentiation|regulation of thymic T cell differentiation					Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.								biological_process											owl:Class	
GO:1905336	biolink:NamedThing	negative regulation of aggrephagy	Any process that stops, prevents or reduces the frequency, rate or extent of aggrephagy.	tmpzr1t_l9r_go_relaxed.owl	down regulation of aggrephagy|inhibition of aggrephagy|downregulation of aggrephagy|down-regulation of aggrephagy							pad	2016-07-26T13:41:54Z					biological_process											owl:Class	
GO:0005200	biolink:NamedThing	structural constituent of cytoskeleton	The action of a molecule that contributes to the structural integrity of a cytoskeletal structure.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0048482	biolink:NamedThing	plant ovule morphogenesis	The process in which the anatomical structures of the ovule are generated and organized. The ovule is the structure in seed plants enclosing the female gametophyte, and is composed of the nucellus, one or two integuments, and the funiculus; it develops into the seed.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0048445	biolink:NamedThing	carpel morphogenesis	The process in which the anatomical structures of the carpel are generated and organized.	tmpzr1t_l9r_go_relaxed.owl												GO:0048430		biological_process											owl:Class	
GO:1901260	biolink:NamedThing	peptidyl-lysine hydroxylation involved in bacterial-type EF-P lysine modification	Any peptidyl-lysine hydroxylation that is involved in bacterial-type EF-P lysine modification.	tmpzr1t_l9r_go_relaxed.owl	EF-P lysine hydroxylation							bf	2012-08-14T13:20:12Z					biological_process											owl:Class	
GO:0072580	biolink:NamedThing	bacterial-type EF-P lysine modification	The modification of a lysine residue in a protein to produce (2S)-2-amino-6-([(3S)-3,6-diaminohexanoyl]amino)hexanoic acid, and the subsequent hydroxylation of the modified lysine residue. This modification is observed in, and is probably unique to, the prokaryotic translation elongation factor P (EF-P).	tmpzr1t_l9r_go_relaxed.owl	EF-P modification pathway					The EF-P modification pathway is now thought to be composed of three steps: conversion of alpha-lysyl-EF-P to beta-lysyl-EF-P, lysylation of Lys34, and hydroxylation of Lys34.		mah	2011-02-07T11:47:33Z					biological_process											owl:Class	
GO:0046860	biolink:NamedThing	glycosome membrane	The lipid bilayer surrounding a glycosome.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0061187	biolink:NamedThing	regulation of ribosomal DNA heterochromatin assembly	Any process that modulates the rate, frequency, or extent of the repression of assembly of rDNA heterochromatin.	tmpzr1t_l9r_go_relaxed.owl	regulation of chromatin silencing at rDNA	https://github.com/geneontology/go-ontology/issues/19238						dph	2010-07-14T09:04:16Z					biological_process											owl:Class	
GO:0000183	biolink:NamedThing	rDNA heterochromatin assembly	The assembly of chromatin characterized by the modified histone H3K9me3, into heterochromatin, resulting in the repression of transcription of rDNA.	tmpzr1t_l9r_go_relaxed.owl	rDNA chromatin silencing|heterochromatic silencing at rDNA|chromatin silencing at ribosomal DNA|chromatin silencing at rDNA	https://github.com/geneontology/go-ontology/issues/19238												biological_process											owl:Class	
GO:1904701	biolink:NamedThing	Wnt-Frizzled-LRP5/6 complex assembly	The aggregation, arrangement and bonding together of a set of components to form a Wnt-Frizzled-LRP5/6 complex.	tmpzr1t_l9r_go_relaxed.owl	WNT-FZD-LRP5 complex assembly|Wnt-induced Frizzled-LRP5/6 complex formation|Frizzled-LRP5/6 complex formation|Wnt-induced Frizzled-LRP5/6 complex assembly|Wnt-FZD-LRP5/6 trimeric complex formation|WNT-FZD-LRP5 complex formation|Wnt-FZD-LRP5/6 trimeric complex assembly|Frizzled-LRP5/6 complex assembly|WNT-FZD-LRP6 complex assembly|WNT-FZD-LRP6 complex formation|Wnt receptor complex assembly							bf	2015-10-01T09:37:57Z					biological_process											owl:Class	
GO:0060944	biolink:NamedThing	neural crest-derived cardiac fibroblast cell fate commitment	The commitment of neural crest cells to a cardiac fibroblast fate and their capacity to differentiate into cardiac fibroblast cells. A cardiac fibroblast is a connective tissue cell in the heart which secretes an extracellular matrix rich in collagen and other macromolecules.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-09-29T02:42:39Z					biological_process											owl:Class	
GO:0060942	biolink:NamedThing	neural crest-derived cardiac fibroblast cell differentiation	The process in which a neural crest cell acquires the specialized structural and/or functional features of a cardiac fibroblast. A cardiac fibroblast is a connective tissue cell in the heart which secretes an extracellular matrix rich in collagen and other macromolecules.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-09-29T01:54:19Z					biological_process											owl:Class	
GO:1990971	biolink:NamedThing	EMILIN complex	Glycoprotein complex of the C1q/TNF superfamily found in the extracellular matrix (ECM) where it is an important component of the elastic fiber system. A homotrimer that will combine to form supramolecular EMILIN structures.	tmpzr1t_l9r_go_relaxed.owl	EMILIN-2 complex|Elastic microfibrillar interface 1 complex|EMILIN-1 complex|Elastic microfibrillar interface 2 complex					An example of this is EMILIN-1 in human (Q9Y6C2) in PMID:10821830 (inferred from direct assay).		bhm	2016-06-21T14:41:18Z					cellular_component											owl:Class	
GO:0086094	biolink:NamedThing	positive regulation of ryanodine-sensitive calcium-release channel activity by adrenergic receptor signaling pathway involved in positive regulation of cardiac muscle contraction	An adrenergic receptor signaling pathway that contributes to an increase in frequency or rate of cardiac muscle contraction through phosphorylation and enhancement of the ryanodine receptor, a calcium-activated calcium-release channel found in the membrane of the sarcoplasmic reticulum. An adrenergic receptor-activated adenylate cyclase generates cAMP. cAMP then activates the cAMP-dependent protein kinase A (PKA), which phosphorylates the ryanodine receptor (RyR). PKA-phosphorylation of RyR enhances channel activity by sensitizing the channel to cytosolic calcium. Cytosolic calcium stimulates contractile proteins to promote muscle contraction.	tmpzr1t_l9r_go_relaxed.owl	adrenergic receptor signaling pathway involved in positive regulation of cardiac muscle contraction via ryanodine receptor phosphorylation							bf						biological_process											owl:Class	
GO:0060452	biolink:NamedThing	positive regulation of cardiac muscle contraction	Any process that increases the frequency, rate or extent of cardiac muscle contraction.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0048636	biolink:NamedThing	positive regulation of muscle organ development	Any process that activates, maintains or increases the rate of muscle development.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of muscle development|up regulation of muscle development|stimulation of muscle development|activation of muscle development|upregulation of muscle development													biological_process											owl:Class	
GO:0007517	biolink:NamedThing	muscle organ development	The process whose specific outcome is the progression of the muscle over time, from its formation to the mature structure. The muscle is an organ consisting of a tissue made up of various elongated cells that are specialized to contract and thus to produce movement and mechanical work.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0014048	biolink:NamedThing	regulation of glutamate secretion	Any process that modulates the frequency, rate or extent of the controlled release of glutamate.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0048492	biolink:NamedThing	ribulose bisphosphate carboxylase complex	A complex containing either both large and small subunits or just small subunits which carries out the activity of producing 3-phosphoglycerate from carbon dioxide and ribulose-1,5-bisphosphate.	tmpzr1t_l9r_go_relaxed.owl	RubisCO complex													cellular_component											owl:Class	
GO:0002428	biolink:NamedThing	antigen processing and presentation of peptide antigen via MHC class Ib	The process in which an antigen-presenting cell expresses peptide antigen in association with an MHC class Ib protein complex on its cell surface. The peptide antigen may originate from an endogenous or exogenous protein. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E family.	tmpzr1t_l9r_go_relaxed.owl	peptide antigen processing and presentation via MHC class Ib													biological_process											owl:Class	
GO:1900677	biolink:NamedThing	positive regulation of F-9775B biosynthetic process	Any process that activates or increases the frequency, rate or extent of F-9775B biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of F-9775B synthesis|positive regulation of F-9775B anabolism|up-regulation of F-9775B biosynthesis|up-regulation of F-9775B biosynthetic process|activation of F-9775B formation|up regulation of F-9775B biosynthetic process|activation of F-9775B anabolism|upregulation of F-9775B biosynthetic process|up-regulation of F-9775B formation|upregulation of F-9775B synthesis|up-regulation of F-9775B anabolism|up regulation of F-9775B synthesis|up regulation of F-9775B biosynthesis|up regulation of F-9775B anabolism|upregulation of F-9775B biosynthesis|up regulation of F-9775B formation|upregulation of F-9775B anabolism|positive regulation of F-9775B formation|activation of F-9775B synthesis|activation of F-9775B biosynthetic process|up-regulation of F-9775B synthesis|activation of F-9775B biosynthesis|upregulation of F-9775B formation|positive regulation of F-9775B biosynthesis							di	2012-05-22T04:27:01Z					biological_process											owl:Class	
GO:1900614	biolink:NamedThing	F-9775B biosynthetic process	The chemical reactions and pathways resulting in the formation of F-9775B.	tmpzr1t_l9r_go_relaxed.owl	F-9775B anabolism|F-9775B synthesis|F-9775B formation|F-9775B biosynthesis							di	2012-05-15T07:03:32Z					biological_process											owl:Class	
GO:0061691	biolink:NamedThing	detoxification of hydrogen peroxide	Any process that reduces or removes the toxicity of hydrogen peroxide. These include transport of hydrogen peroxide away from sensitive areas and to compartments or complexes whose purpose is sequestration.	tmpzr1t_l9r_go_relaxed.owl								dph	2015-05-05T12:42:18Z					biological_process											owl:Class	
GO:0042542	biolink:NamedThing	response to hydrogen peroxide	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrogen peroxide (H2O2) stimulus.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0012501	biolink:NamedThing	programmed cell death	A process which begins when a cell receives an internal or external signal and activates a series of biochemical events (signaling pathway). The process ends with the death of the cell.	tmpzr1t_l9r_go_relaxed.owl	regulated cell death|caspase-independent cell death|nonapoptotic programmed cell death|caspase-independent apoptosis|PCD|non-apoptotic programmed cell death|RCD				Wikipedia:Programmed_cell_death	Note that this term should be used to annotate gene products in the organism undergoing the programmed cell death. To annotate genes in another organism whose products modulate programmed cell death in a host organism, consider the term 'modulation by symbiont of host programmed cell death ; GO:0052040'. Also, note that 'programmed cell death ; GO:0012501' should be used to refer to instances of caspase-independent cell death mechanisms, in the absence of further indications on the process taking place. At present, caspase-independent cell death is not yet represented in GO due to the lack of consensus and in-depth research on the topic. 'programmed cell death ; GO:0012501' may also be used to annotate gene products in taxa where apoptosis as defined in GO:0006915 does not occur, such as plants. You may also consider these specific children: GO:0097468 'programmed cell death in response to reactive oxygen species' (with descendants GO:0010421 'hydrogen peroxide-mediated programmed cell death' and GO:0010343 'singlet oxygen-mediated programmed cell death'), and GO:0009626 'plant-type hypersensitive response' and its children.						GO:0016244		biological_process											owl:Class	
GO:0060879	biolink:NamedThing	semicircular canal fusion	Creation of the central hole of the semicircular canal by sealing the edges of the pouch that forms during the process of semicircular canal formation.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-08-13T10:05:51Z					biological_process											owl:Class	
GO:0003714	biolink:NamedThing	transcription corepressor activity	A transcription coregulator activity that represses or decreases the transcription of specific gene sets via binding to a DNA-bound DNA-binding transcription factor, either on its own or as part of a complex. Corepressors often act by altering chromatin structure and modifications. For example, one class of transcription corepressors modifies chromatin structure through covalent modification of histones. A second class remodels the conformation of chromatin in an ATP-dependent fashion. A third class modulates interactions of DNA-bound DNA-binding transcription factors with other transcription coregulators.	tmpzr1t_l9r_go_relaxed.owl	RNA polymerase II transcription corepressor activity|RNA polymerase II transcription co-repressor activity|transcription co-repressor activity	https://github.com/geneontology/go-ontology/issues/15665|https://github.com/geneontology/go-ontology/issues/20464|https://github.com/geneontology/go-ontology/issues/15998				For usage guidance, see comment in GO:0003712 ; transcription coregulator activity.		krc	2010-11-24T03:14:44Z			GO:0001106		molecular_function											owl:Class	
GO:0045248	biolink:NamedThing	cytosolic oxoglutarate dehydrogenase complex	A cytosolic complex of multiple copies of three enzymatic components: oxoglutarate dehydrogenase (lipoamide) ; EC:1.2.4.2 (E1), dihydrolipoamide S-succinyltransferase ; EC:2.3.1.61 (E2) and dihydrolipoamide dehydrogenase ; EC:1.8.1.4 (E3); catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and carbon dioxide (CO2).	tmpzr1t_l9r_go_relaxed.owl						See also the molecular functions term 'oxoglutarate dehydrogenase (succinyl-transferring) activity ; GO:0004591', 'dihydrolipoyllysine-residue succinyltransferase activity ; GO:0004149' and 'dihydrolipoyl dehydrogenase activity ; GO:0004148'.								cellular_component											owl:Class	
GO:0032815	biolink:NamedThing	negative regulation of natural killer cell activation	Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer cell activation.	tmpzr1t_l9r_go_relaxed.owl	downregulation of natural killer cell activation|inhibition of natural killer cell activation|negative regulation of NK cell activation|down regulation of natural killer cell activation|down-regulation of natural killer cell activation													biological_process											owl:Class	
GO:0030101	biolink:NamedThing	natural killer cell activation	The change in morphology and behavior of a natural killer cell in response to a cytokine, chemokine, cellular ligand, or soluble factor.	tmpzr1t_l9r_go_relaxed.owl	NK cell activation													biological_process											owl:Class	
GO:0072224	biolink:NamedThing	metanephric glomerulus development	The progression of the metanephric glomerulus over time from its initial formation until its mature state. The metanephric glomerulus is a capillary tuft which forms a close network with the visceral epithelium (podocytes) and the mesangium to form the filtration barrier and is surrounded by Bowman's capsule in nephrons of the mature vertebrate kidney, or metanephros.	tmpzr1t_l9r_go_relaxed.owl	metanephric glomerular development							mah	2010-03-18T03:36:20Z					biological_process											owl:Class	
GO:0044214	biolink:NamedThing	spanning component of plasma membrane	The component of the plasma membrane consisting of gene products and protein complexes that have some part that spans both leaflets of the membrane.	tmpzr1t_l9r_go_relaxed.owl	fully spanning plasma membrane|transmembrane					Proteins that span the membrane but have the bulk on one side of the membrane may be additionally annotated with a term of the form integral to X side of the plasma membrane.		jl	2009-11-04T01:50:57Z					cellular_component											owl:Class	
GO:0005886	biolink:NamedThing	plasma membrane	The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.	tmpzr1t_l9r_go_relaxed.owl	inner endospore membrane|plasmalemma|cellular membrane|bacterial inner membrane|cell membrane|plasma membrane lipid bilayer|cytoplasmic membrane|juxtamembrane				Wikipedia:Cell_membrane|NIF_Subcellular:sao1663586795							GO:0005904		cellular_component											owl:Class	
GO:0031306	biolink:NamedThing	intrinsic component of mitochondrial outer membrane	The component of the mitochondrial outer membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.	tmpzr1t_l9r_go_relaxed.owl	intrinsic to mitochondrial outer membrane													cellular_component											owl:Class	
GO:0005741	biolink:NamedThing	mitochondrial outer membrane	The outer, i.e. cytoplasm-facing, lipid bilayer of the mitochondrial envelope.	tmpzr1t_l9r_go_relaxed.owl	mitochondrion outer membrane|outer mitochondrion membrane|outer mitochondrial membrane				Wikipedia:Outer_mitochondrial_membrane|NIF_Subcellular:sao1289741256									cellular_component											owl:Class	
GO:0072049	biolink:NamedThing	comma-shaped body morphogenesis	The process in which the comma-shaped body is generated and organized. The comma-shaped body is the precursor structure to the S-shaped body that contributes to the morphogenesis of the nephron.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-01-25T03:44:48Z					biological_process											owl:Class	
GO:0072028	biolink:NamedThing	nephron morphogenesis	The process in which the anatomical structures of the nephron are generated and organized. A nephron is the functional unit of the kidney.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-01-25T02:45:52Z					biological_process											owl:Class	
GO:0044106	biolink:NamedThing	cellular amine metabolic process	The chemical reactions and pathways involving any organic compound that is weakly basic in character and contains an amino or a substituted amino group, as carried out by individual cells. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom.	tmpzr1t_l9r_go_relaxed.owl								jl	2009-07-15T11:55:44Z					biological_process											owl:Class	
GO:0002362	biolink:NamedThing	CD4-positive, CD25-positive, alpha-beta regulatory T cell lineage commitment	The process in which a CD4-positive, alpha-beta T cell becomes committed to becoming a CD4-positive, CD25-positive, alpha-beta regulatory T cell.	tmpzr1t_l9r_go_relaxed.owl	CD4-positive, CD25-positive, alpha-beta regulatory T-lymphocyte lineage commitment|CD4-positive, CD25-positive, alpha-beta regulatory T-cell lineage commitment|CD4-positive, CD25-positive, alpha-beta regulatory T lymphocyte lineage commitment													biological_process											owl:Class	
GO:1900166	biolink:NamedThing	regulation of glial cell-derived neurotrophic factor production	Any process that modulates the frequency, rate or extent of glial cell-derived neurotrophic factor production.	tmpzr1t_l9r_go_relaxed.owl	regulation of GDNF secretion|regulation of glial cell line-derived neurotrophic factor secretion|regulation of glial cell-derived neurotrophic factor secretion							yaf	2012-03-08T03:44:39Z					biological_process											owl:Class	
GO:0044467	biolink:NamedThing	glial cell-derived neurotrophic factor production	The regulated release of glial cell line-derived neurotrophic factor from a cell. Glial cell-derived neurotrophic factor (GDNF) is a small protein that potently promotes the survival of many types of neurons, notably dopaminergic and motor neurons.	tmpzr1t_l9r_go_relaxed.owl	glial cell line-derived neurotrophic factor production|GDNF production|glial cell-derived neurotrophic factor secretion							jl	2012-01-17T04:26:05Z					biological_process											owl:Class	
GO:0010660	biolink:NamedThing	regulation of muscle cell apoptotic process	Any process that modulates the rate or frequency of muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a muscle cell and result in its death.	tmpzr1t_l9r_go_relaxed.owl	regulation of muscle cell apoptosis													biological_process											owl:Class	
GO:0010657	biolink:NamedThing	muscle cell apoptotic process	A form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases, whose actions dismantle a muscle cell and result in its death. A muscle cell is a mature contractile cell, commonly known as a myocyte, that forms one of three kinds of muscle.	tmpzr1t_l9r_go_relaxed.owl	muscle cell apoptosis													biological_process											owl:Class	
GO:0003041	biolink:NamedThing	excitation of vasomotor center by carotid body chemoreceptor signaling	The process in which the molecular signal from a carotid body is relayed to the vasomotor center, causing it to signal an increase arterial pressure.	tmpzr1t_l9r_go_relaxed.owl	excitation of vasomotor center by carotid body chemoreceptor signalling													biological_process											owl:Class	
GO:0003027	biolink:NamedThing	regulation of systemic arterial blood pressure by carotid body chemoreceptor signaling	The process that modulates blood pressure by the action of chemoreceptors found in the carotid bodies and their resultant modulation of the vasomotor center. Chemoreceptors respond to oxygen, carbon dioxide and hydrogen ions.	tmpzr1t_l9r_go_relaxed.owl	regulation of systemic arterial blood pressure by carotid body chemoreceptor signalling|carotid body chemoreceptor regulation of systemic arterial blood pressure|vagal reflex|carotid body chemoreceptor response to lowering of systemic arterial blood pressure													biological_process											owl:Class	
GO:0006694	biolink:NamedThing	steroid biosynthetic process	The chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus; includes de novo formation and steroid interconversion by modification.	tmpzr1t_l9r_go_relaxed.owl	steroid synthesis|steroid anabolism|steroid biosynthesis|steroidogenesis|steroid formation				Wikipedia:Steroid_metabolisms#Steroid_biosynthesis									biological_process											owl:Class	
GO:0061050	biolink:NamedThing	regulation of cell growth involved in cardiac muscle cell development	Any process that modulates the rate, frequency, or extent of the growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-02-25T01:05:16Z					biological_process											owl:Class	
GO:0035483	biolink:NamedThing	gastric emptying	The process in which the liquid and liquid-suspended solid contents of the stomach exit through the pylorus into the duodenum.	tmpzr1t_l9r_go_relaxed.owl								bf	2010-04-23T10:51:33Z					biological_process											owl:Class	
GO:0004862	biolink:NamedThing	cAMP-dependent protein kinase inhibitor activity	Binds to and stops, prevents or reduces the activity of a cAMP-dependent protein kinase.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-180073									molecular_function											owl:Class	
GO:0071613	biolink:NamedThing	granzyme B production	The appearance of granzyme B due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	tmpzr1t_l9r_go_relaxed.owl						Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.		mah	2010-02-05T04:47:15Z					biological_process											owl:Class	
GO:0001859	biolink:NamedThing	complement component C3dg receptor activity	Combining with the C3dg product of the complement cascade and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0001853	biolink:NamedThing	complement component C3dg binding	Binding to a C3dg product of the complement cascade.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0070197	biolink:NamedThing	meiotic attachment of telomere to nuclear envelope	The meiotic cell cycle process in which physical connections are formed between telomeric heterochromatin and the nuclear envelope, facilitating bouquet formation.	tmpzr1t_l9r_go_relaxed.owl	attachment of telomeric chromatin to nuclear envelope|attachment of telomeres to nuclear envelope	https://github.com/geneontology/go-ontology/issues/22043												biological_process											owl:Class	
GO:0044821	biolink:NamedThing	meiotic telomere tethering at nuclear periphery	The process in which a telomere is maintained in a specific location at the nuclear periphery, as part of a meiotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl								jl	2013-11-19T16:18:09Z					biological_process											owl:Class	
GO:0003289	biolink:NamedThing	atrial septum primum morphogenesis	The process in which anatomical structure of an atrial septum primum is generated and organized.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-10-20T10:32:32Z					biological_process											owl:Class	
GO:0003284	biolink:NamedThing	septum primum development	The progression of the septum primum over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-10-20T10:12:26Z					biological_process											owl:Class	
GO:0055104	biolink:NamedThing	ligase inhibitor activity	Binds to and stops, prevents or reduces the activity of a ligase.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:2000533	biolink:NamedThing	negative regulation of renal albumin absorption	Any process that stops, prevents or reduces the frequency, rate or extent of renal albumin absorption.	tmpzr1t_l9r_go_relaxed.owl								pr	2011-03-24T03:28:11Z					biological_process											owl:Class	
GO:0097018	biolink:NamedThing	renal albumin absorption	A renal system process in which albumin is taken up from the collecting ducts, glomerulus and proximal and distal loops of the nephron.	tmpzr1t_l9r_go_relaxed.owl								pr	2011-03-23T03:15:04Z					biological_process											owl:Class	
GO:1902989	biolink:NamedThing	meiotic telomere maintenance via semi-conservative replication	Any telomere maintenance via semi-conservative replication that is involved in meiotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl	equal telomere replication involved in meiotic cell cycle|telomeric fork progression involved in meiotic cell cycle|telomeric replication fork progression involved in meiotic cell cycle							jl	2014-05-08T11:13:43Z					biological_process											owl:Class	
GO:0075215	biolink:NamedThing	modulation of spore encystment on host	Any process that modulates the frequency, rate or extent of spore encystment on host. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0075214	biolink:NamedThing	spore encystment	The physiological, developmental and morphological changes that occur in a symbiont spore during the process of its encystment. Encystment means to enter a state of essentially suspended animation in which the spore is protected by an outer coating and remains immobile and inactive until favorable conditions for growth occur again. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	spore encystment on host													biological_process											owl:Class	
GO:2000856	biolink:NamedThing	negative regulation of mineralocorticoid secretion	Any process that stops, prevents or reduces the frequency, rate or extent of mineralocorticoid secretion.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-07-26T08:46:42Z					biological_process											owl:Class	
GO:0035931	biolink:NamedThing	mineralocorticoid secretion	The regulated release of any mineralocorticoid into the circulatory system. Mineralocorticoids are a class of steroid hormones that regulate water and electrolyte metabolism.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-07-20T01:04:59Z					biological_process											owl:Class	
GO:0033182	biolink:NamedThing	regulation of histone ubiquitination	Any process that modulates the frequency, rate or extent of the addition of a ubiquitin group to a histone protein.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0016574	biolink:NamedThing	histone ubiquitination	The modification of histones by addition of ubiquitin groups.	tmpzr1t_l9r_go_relaxed.owl	histone ubiquitinylation|histone ubiquitylation													biological_process											owl:Class	
GO:1901224	biolink:NamedThing	positive regulation of NIK/NF-kappaB signaling	Any process that activates or increases the frequency, rate or extent of NIK/NF-kappaB signaling.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of non-canonical NF-KB signaling|up-regulation of p52-dependent NF-kappaB signaling|release of NF-kappaB sequestered in cytoplasm|activation of p52-dependent NF-kappaB signaling|upregulation of p52-dependent NF-kappaB signaling|up-regulation of noncanonical nuclear factor kappaB (NF-kappaB) pathway|up regulation of NIK/NF-kappaB cascade|upregulation of NIK/NF-kappaB cascade|release of cytoplasmic sequestered NF-kappaB|up-regulation of noncanonical NF-kappaB signaling|upregulation of non-canonical NF-KB signaling|positive regulation of noncanonical NF-kappaB signaling|upregulation of noncanonical nuclear factor kappaB (NF-kappaB) pathway|positive regulation of NIK/NF-kappaB cascade|up regulation of noncanonical NF-kappaB signaling|positive regulation of NF-kappaB import into nucleus|up regulation of non-canonical NF-KB signaling|negative regulation of cytoplasmic NF-kappaB storage|up regulation of p52-dependent NF-kappaB signaling|activation of non-canonical NF-KB signaling|positive regulation of non-canonical NF-KB signaling|up regulation of noncanonical nuclear factor kappaB (NF-kappaB) pathway|activation of noncanonical nuclear factor kappaB (NF-kappaB) pathway|up-regulation of NIK/NF-kappaB cascade|positive regulation of noncanonical nuclear factor kappaB (NF-kappaB) pathway|positive regulation of p52-dependent NF-kappaB signaling|activation of NIK/NF-kappaB cascade|activation of noncanonical NF-kappaB signaling|upregulation of noncanonical NF-kappaB signaling							hjd	2012-08-06T20:27:47Z			GO:0008588|GO:0042346		biological_process											owl:Class	
GO:0038061	biolink:NamedThing	NIK/NF-kappaB signaling	The process in which a signal is passed on to downstream components within the cell through the NIK-dependent processing and activation of NF-KappaB. Begins with activation of the NF-KappaB-inducing kinase (NIK), which in turn phosphorylates and activates IkappaB kinase alpha (IKKalpha). IKKalpha phosphorylates the NF-Kappa B2 protein (p100) leading to p100 processing and release of an active NF-KappaB (p52).	tmpzr1t_l9r_go_relaxed.owl	NIK/NF-kappaB cascade|noncanonical nuclear factor kappaB (NF-kappaB) pathway|non-canonical NF-KB signaling|noncanonical NF-kappaB signaling|p52-dependent NF-kappaB signaling|NIK/NF-kappaB signal transduction							bf	2012-01-16T05:44:46Z					biological_process											owl:Class	
GO:2000860	biolink:NamedThing	positive regulation of aldosterone secretion	Any process that activates or increases the frequency, rate or extent of aldosterone secretion.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-07-26T08:47:34Z					biological_process											owl:Class	
GO:0035932	biolink:NamedThing	aldosterone secretion	The regulated release of aldosterone into the circulatory system. Aldosterone is a pregnane-based steroid hormone produced by the outer-section (zona glomerulosa) of the adrenal cortex in the adrenal gland, and acts on the distal tubules and collecting ducts of the kidney to cause the conservation of sodium, secretion of potassium, increased water retention, and increased blood pressure. The overall effect of aldosterone is to increase reabsorption of ions and water in the kidney.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-07-20T01:06:24Z					biological_process											owl:Class	
GO:0042042	biolink:NamedThing	tungsten incorporation into tungsten-molybdopterin complex	The incorporation of tungsten into a tungsten-molybdopterin complex.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1900939	biolink:NamedThing	negative regulation of (Z)-nonadeca-1,14-diene metabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of (Z)-nonadeca-1,14-diene metabolic process.	tmpzr1t_l9r_go_relaxed.owl	down regulation of (Z)-nonadeca-1,14-diene metabolic process|down-regulation of (Z)-nonadeca-1,14-diene metabolism|down regulation of (Z)-nonadeca-1,14-diene metabolism|inhibition of (Z)-nonadeca-1,14-diene metabolism|inhibition of (Z)-nonadeca-1,14-diene metabolic process|downregulation of (Z)-nonadeca-1,14-diene metabolism|downregulation of (Z)-nonadeca-1,14-diene metabolic process|negative regulation of (Z)-nonadeca-1,14-diene metabolism|down-regulation of (Z)-nonadeca-1,14-diene metabolic process							tt	2012-06-14T03:15:58Z					biological_process											owl:Class	
GO:1900878	biolink:NamedThing	(Z)-nonadeca-1,14-diene metabolic process	The chemical reactions and pathways involving (Z)-nonadeca-1,14-diene.	tmpzr1t_l9r_go_relaxed.owl	(Z)-nonadeca-1,14-diene metabolism							tt	2012-06-13T02:09:18Z					biological_process											owl:Class	
GO:1901433	biolink:NamedThing	positive regulation of response to cycloalkane	Any process that activates or increases the frequency, rate or extent of response to cycloalkane.	tmpzr1t_l9r_go_relaxed.owl	upregulation of response to cycloalkane|activation of response to cycloalkane|up-regulation of response to cycloalkane|up regulation of response to cycloalkane							tt	2012-10-01T21:03:26Z					biological_process											owl:Class	
GO:0014071	biolink:NamedThing	response to cycloalkane	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cycloalkane stimulus. A cycloalkane is a cyclic saturated hydrocarbon having the general formula CnH2n.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:2000692	biolink:NamedThing	negative regulation of seed maturation	Any process that stops, prevents or reduces the frequency, rate or extent of seed maturation.	tmpzr1t_l9r_go_relaxed.owl								dhl	2011-05-13T06:41:43Z					biological_process											owl:Class	
GO:1902106	biolink:NamedThing	negative regulation of leukocyte differentiation	Any process that stops, prevents or reduces the frequency, rate or extent of leukocyte differentiation.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of immune cell differentiation|inhibition of immune cell differentiation|negative regulation of leucocyte differentiation|down-regulation of immune cell differentiation|down-regulation of leukocyte differentiation|down-regulation of leucocyte differentiation|downregulation of leucocyte differentiation|downregulation of leukocyte differentiation|down regulation of leukocyte differentiation|inhibition of leukocyte differentiation|down regulation of leucocyte differentiation|down regulation of immune cell differentiation|downregulation of immune cell differentiation|inhibition of leucocyte differentiation							pr	2013-05-02T17:32:47Z					biological_process											owl:Class	
GO:0002521	biolink:NamedThing	leukocyte differentiation	The process in which a relatively unspecialized hemopoietic precursor cell acquires the specialized features of a leukocyte. A leukocyte is an achromatic cell of the myeloid or lymphoid lineages capable of ameboid movement, found in blood or other tissue.	tmpzr1t_l9r_go_relaxed.owl	leucocyte differentiation|immune cell differentiation													biological_process											owl:Class	
GO:0003372	biolink:NamedThing	establishment or maintenance of cytoskeleton polarity involved in mesendodermal cell migration	Any cellular process that results in the specification, formation or maintenance of polarized cytoskeletal structures that contribute to the cell polarity of a migrating mesendodermal cell.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-12-08T05:46:23Z					biological_process											owl:Class	
GO:0003369	biolink:NamedThing	establishment of cell polarity involved in mesendodermal cell migration	The specification and formation of anisotropic intracellular organization that contributes to the self-propelled directed movement of a mesendodermal cell.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-12-08T05:31:51Z					biological_process											owl:Class	
GO:0072044	biolink:NamedThing	collecting duct development	The process whose specific outcome is the progression of a collecting duct over time, from its formation to the mature structure. The collecting duct responds to vasopressin and aldosterone to regulate water, electrolyte and acid-base balance. It is the final common path through which urine flows before entering the ureter and then emptying into the bladder.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-01-25T03:18:06Z					biological_process											owl:Class	
GO:0001822	biolink:NamedThing	kidney development	The process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and/or excretes the end products of body metabolism in the form of urine.	tmpzr1t_l9r_go_relaxed.owl	nephrogenesis				Wikipedia:Kidney_development									biological_process											owl:Class	
GO:0038199	biolink:NamedThing	ethylene receptor activity	Combining with ethylene and transmitting the signal in the cell to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	C2H4 receptor activity|ethylene response sensor							bf	2013-12-05T16:06:13Z					molecular_function											owl:Class	
GO:0016469	biolink:NamedThing	proton-transporting two-sector ATPase complex	A large protein complex that catalyzes the synthesis or hydrolysis of ATP by a rotational mechanism, coupled to the transport of protons across a membrane. The complex comprises a membrane sector (F0, V0, or A0) that carries out proton transport and a cytoplasmic compartment sector (F1, V1, or A1) that catalyzes ATP synthesis or hydrolysis. Two major types have been characterized: V-type ATPases couple ATP hydrolysis to the transport of protons across a concentration gradient, whereas F-type ATPases, also known as ATP synthases, normally run in the reverse direction to utilize energy from a proton concentration or electrochemical gradient to synthesize ATP. A third type, A-type ATPases have been found in archaea, and are closely related to eukaryotic V-type ATPases but are reversible.	tmpzr1t_l9r_go_relaxed.owl	vacuolar hydrogen-transporting ATPase|hydrogen-transporting two-sector ATPase complex													cellular_component											owl:Class	
GO:0048800	biolink:NamedThing	antennal morphogenesis	The process in which the anatomical structures of the antenna are generated and organized.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0007469	biolink:NamedThing	antennal development	The process whose specific outcome is the progression of the antenna over time, from its formation to the mature structure. The antenna are the sensory structures on the head that are capable of detecting various environmental stimuli.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0071003	biolink:NamedThing	penta-snRNP complex	A ribonucleoprotein complex that is formed by the association of the U1, U2, U4/U6 and U5 small nuclear ribonucleoproteins.	tmpzr1t_l9r_go_relaxed.owl	penta-RNP complex							mah	2009-07-30T12:00:35Z					cellular_component											owl:Class	
GO:0005686	biolink:NamedThing	U2 snRNP	A ribonucleoprotein complex that contains small nuclear RNA U2, a heptameric ring of Sm proteins, as well as several proteins that are unique to the U2 snRNP, most of which remain associated with the U2 snRNA both while the U2 snRNP is free or assembled into a series of spliceosomal complexes.	tmpzr1t_l9r_go_relaxed.owl	snRNP U2|17S U2 snRNP					U2 snRNP refers to the U2 small nuclear RNA and the proteins that associate with it. U2 snRNP is not considered to be a type of spliceosomal complex by itself.								cellular_component											owl:Class	
GO:0030717	biolink:NamedThing	oocyte karyosome formation	The chromosome organization process in which meiotic chromosomes in the oocyte nucleus cluster together to form a compact spherical structure called the karyosome.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0051299	biolink:NamedThing	centrosome separation	The process in which duplicated centrosome components move away from each other. The centriole pair within each centrosome becomes part of a separate microtubule organizing center that nucleates a radial array of microtubules called an aster. The two asters move to opposite sides of the nucleus to form the two poles of the mitotic spindle.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0072114	biolink:NamedThing	pronephros morphogenesis	The process in which the anatomical structures of the pronephros are generated and organized. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life.	tmpzr1t_l9r_go_relaxed.owl	pronephric kidney morphogenesis							mah	2010-02-22T11:12:15Z					biological_process											owl:Class	
GO:0007519	biolink:NamedThing	skeletal muscle tissue development	The developmental sequence of events leading to the formation of adult skeletal muscle tissue. The main events are: the fusion of myoblasts to form myotubes that increase in size by further fusion to them of myoblasts, the formation of myofibrils within their cytoplasm and the establishment of functional neuromuscular junctions with motor neurons. At this stage they can be regarded as mature muscle fibers.	tmpzr1t_l9r_go_relaxed.owl	myogenesis											GO:0048637		biological_process											owl:Class	
GO:0000262	biolink:NamedThing	mitochondrial chromosome	A chromosome found in the mitochondrion of a eukaryotic cell.	tmpzr1t_l9r_go_relaxed.owl	mitochondrial DNA|mtDNA|mitochondrial genome				NIF_Subcellular:sao1186327184									cellular_component											owl:Class	
GO:1903099	biolink:NamedThing	positive regulation of CENP-A containing nucleosome assembly	Any process that activates or increases the frequency, rate or extent of the formation of nucleosomes containing the histone H3 variant CENP-A to form centromeric chromatin. This specialised chromatin occurs at centromeric region in point centromeres,  and the central core in modular centromeres.	tmpzr1t_l9r_go_relaxed.owl	activation of CenH3-containing nucleosome assembly at centromere|up regulation of centromere-specific histone exchange|upregulation of centromeric DNA replication-independent nucleosome assembly|upregulation of CENP-A containing nucleosome assembly at centromere|up-regulation of CENP-A containing nucleosome assembly at centromere|upregulation of CenH3-containing nucleosome assembly at centromere|up regulation of CenH3-containing nucleosome assembly at centromere|activation of CENP-A deposition|activation of centromere-specific histone exchange|up regulation of CENP-A deposition|up regulation of DNA replication-independent nucleosome assembly at centromere|up-regulation of centromeric DNA replication-independent nucleosome assembly|upregulation of centromere-specific nucleosome assembly|activation of centromere specific nucleosome exchange|upregulation of DNA replication-independent nucleosome assembly at centromere|positive regulation of DNA replication-independent nucleosome assembly at centromere|up-regulation of centromere specific nucleosome exchange|up regulation of centromere-specific nucleosome assembly|up-regulation of CENP-A deposition|positive regulation of centromeric DNA replication-independent nucleosome assembly|positive regulation of CENP-A loading|upregulation of centromere specific nucleosome exchange|up-regulation of CenH3-containing nucleosome assembly at centromere|positive regulation of centromere-specific nucleosome assembly|up-regulation of DNA replication-independent nucleosome assembly at centromere|upregulation of CENP-A loading|up regulation of centromere specific nucleosome exchange|positive regulation of CENP-A deposition|up regulation of CENP-A containing nucleosome assembly at centromere|activation of CENP-A loading|up regulation of CENP-A loading|positive regulation of centromere specific nucleosome exchange|upregulation of CENP-A deposition|activation of centromeric DNA replication-independent nucleosome assembly|upregulation of centromere-specific histone exchange|up-regulation of centromere-specific nucleosome assembly|up-regulation of centromere-specific histone exchange|activation of DNA replication-independent nucleosome assembly at centromere|up regulation of centromeric DNA replication-independent nucleosome assembly|activation of centromere-specific nucleosome assembly|positive regulation of CenH3-containing nucleosome assembly at centromere|activation of CENP-A containing nucleosome assembly at centromere|up-regulation of CENP-A loading|positive regulation of centromere-specific histone exchange							vw	2014-06-03T16:15:42Z					biological_process											owl:Class	
GO:0032433	biolink:NamedThing	filopodium tip	The end of a filopodium distal to the body of the cell.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0030175	biolink:NamedThing	filopodium	Thin, stiff, actin-based protrusion extended by the leading edge of a motile cell such as a crawling fibroblast or amoeba, or an axonal or dendritic growth cone, or a dendritic shaft.	tmpzr1t_l9r_go_relaxed.owl					NIF_Subcellular:sao1046371754|Wikipedia:Filopodia	A filopodium may be approximately 0.1 um wide, 5-10 um long, and up to 50 um long in axon growth cones; contain a loose bundle of about 20 actin filaments oriented with their plus ends pointing outward. Note that filopodia on dendritic shafts are distinct from other types of filopodia (even those found in dendritic growth cones) and may react differently to stimuli, as shown in PMID:12904473.						GO:0030028		cellular_component											owl:Class	
GO:0045796	biolink:NamedThing	negative regulation of intestinal cholesterol absorption	Any process that stops, prevents, or reduces the frequency, rate or extent of uptake of cholesterol into the blood by absorption from the intestine.	tmpzr1t_l9r_go_relaxed.owl	inhibition of cholesterol absorption|down regulation of cholesterol absorption|down-regulation of cholesterol absorption|downregulation of cholesterol absorption													biological_process											owl:Class	
GO:0030299	biolink:NamedThing	intestinal cholesterol absorption	Uptake of cholesterol into the blood by absorption from the small intestine.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0048557	biolink:NamedThing	embryonic digestive tract morphogenesis	The process in which the anatomical structures of the digestive tract are generated and organized during embryonic development. The digestive tract is the anatomical structure through which food passes and is processed.	tmpzr1t_l9r_go_relaxed.owl	embryonic gut morphogenesis											GO:0048558		biological_process											owl:Class	
GO:0048546	biolink:NamedThing	digestive tract morphogenesis	The process in which the anatomical structures of the digestive tract are generated and organized. The digestive tract is the anatomical structure through which food passes and is processed.	tmpzr1t_l9r_go_relaxed.owl	gastrointestinal tract morphogenesis|digestive tube morphogenesis|gut morphogenesis|intestinal morphogenesis|alimentary canal morphogenesis											GO:0048547		biological_process											owl:Class	
GO:0055110	biolink:NamedThing	involution involved in gastrulation with mouth forming second	The inturning of an epithelial sheet over the basal surface of an outer layer involved in deuterostomic gastrulation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0001702	biolink:NamedThing	gastrulation with mouth forming second	A gastrulation process in which the initial invagination becomes the anus and the mouth forms second.	tmpzr1t_l9r_go_relaxed.owl	deuterostomic gastrulation											GO:0010003|GO:0048276		biological_process											owl:Class	
GO:0006906	biolink:NamedThing	vesicle fusion	Fusion of the membrane of a transport vesicle with its target membrane.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1902547	biolink:NamedThing	regulation of cellular response to vascular endothelial growth factor stimulus	Any process that modulates the frequency, rate or extent of cellular response to vascular endothelial growth factor stimulus.	tmpzr1t_l9r_go_relaxed.owl	regulation of cellular response to VEGF|regulation of cellular response to VEGFA|regulation of cellular response to vascular endothelial growth factor|regulation of cellular response to VEGFB							rl	2013-12-04T15:14:54Z					biological_process											owl:Class	
GO:0035924	biolink:NamedThing	cellular response to vascular endothelial growth factor stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vascular endothelial growth factor stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to vascular endothelial growth factor|cellular response to VEGFB|cellular response to VEGF|cellular response to VEGFA							bf	2011-07-15T04:03:29Z					biological_process											owl:Class	
GO:1990100	biolink:NamedThing	DnaB-DnaC complex	A protein complex containing homohexameric DNA helicase DnaB, and the DNA helicase loader DnaC. The helicase loader DnaC delivers DnaB to the chromosomal origin (oriC).	tmpzr1t_l9r_go_relaxed.owl	helicase-loading complex|DnaB6-DnaC6 complex|DnaB6-DnaC3 complex					DnaB and DnaC may be present in different ratios in different forms of the DnaB-DnaC complex, including a DnaB6-DnaC3 complex active at the oriC, and a DnaB6-DnaC6 complex.		bhm	2013-05-14T12:02:22Z					cellular_component											owl:Class	
GO:0036168	biolink:NamedThing	filamentous growth of a population of unicellular organisms in response to heat	The process in which a group of unicellular organisms grow in a threadlike, filamentous shape in response to an increase in temperature.	tmpzr1t_l9r_go_relaxed.owl								bf	2012-03-27T03:53:28Z					biological_process											owl:Class	
GO:0072515	biolink:NamedThing	trehalose transport in response to desiccation	The directed movement of trehalose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore, that occurs as a result of a desiccation stimulus. A desiccation stimulus signals extreme dryness resulting from the prolonged deprivation of water.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-12-21T11:30:31Z					biological_process											owl:Class	
GO:0071465	biolink:NamedThing	cellular response to desiccation	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a desiccation stimulus, extreme dryness resulting from the prolonged deprivation of water.	tmpzr1t_l9r_go_relaxed.owl	desiccation tolerance							mah	2009-12-18T11:35:19Z					biological_process											owl:Class	
GO:0021667	biolink:NamedThing	rhombomere 6 morphogenesis	The process in which the anatomical structure of rhombomere 6 is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0021572	biolink:NamedThing	rhombomere 6 development	The process whose specific outcome is the progression of rhombomere 6 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0021638	biolink:NamedThing	trigeminal nerve formation	The process that gives rise to the trigeminal nerve. This process pertains to the initial formation of a structure from unspecified parts. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains sensory branches that reach the pterygopalatine fossa via the inferior orbital fissure (face, cheek and upper teeth) and pterygopalatine canal (soft and hard palate, nasal cavity and pharynx). The motor part of the mandibular branch is distributed to the muscles of mastication, the mylohyoid muscle and the anterior belly of the digastric. The mandibular nerve also innervates the tensor veli palatini and tensor tympani muscles. The sensory part of the mandibular nerve is composed of branches that carry general sensory information from the mucous membranes of the mouth and cheek, anterior two-thirds of the tongue, lower teeth, skin of the lower jaw, side of the head and scalp and meninges of the anterior and middle cranial fossae.	tmpzr1t_l9r_go_relaxed.owl	CN V biosynthesis|CN V formation													biological_process											owl:Class	
GO:0021636	biolink:NamedThing	trigeminal nerve morphogenesis	The process in which the anatomical structure of the trigeminal nerve is generated and organized. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains sensory branches that reach the pterygopalatine fossa via the inferior orbital fissure (face, cheek and upper teeth) and pterygopalatine canal (soft and hard palate, nasal cavity and pharynx). The motor part of the mandibular branch is distributed to the muscles of mastication, the mylohyoid muscle and the anterior belly of the digastric. The mandibular nerve also innervates the tensor veli palatini and tensor tympani muscles. The sensory part of the mandibular nerve is composed of branches that carry general sensory information from the mucous membranes of the mouth and cheek, anterior two-thirds of the tongue, lower teeth, skin of the lower jaw, side of the head and scalp and meninges of the anterior and middle cranial fossae.	tmpzr1t_l9r_go_relaxed.owl	CN V morphogenesis													biological_process											owl:Class	
GO:1901191	biolink:NamedThing	negative regulation of formation of translation initiation ternary complex	Any process that stops, prevents or reduces the frequency, rate or extent of formation of translation initiation ternary complex.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of translation initiation ternary complex assembly|inhibition of translation initiation ternary complex assembly|downregulation of formation of translation initiation ternary complex|negative regulation of translation initiation ternary complex assembly|down regulation of translation initiation ternary complex assembly|downregulation of translation initiation ternary complex assembly|down regulation of formation of translation initiation ternary complex|inhibition of formation of translation initiation ternary complex|down-regulation of formation of translation initiation ternary complex							ss	2012-07-25T02:27:21Z					biological_process											owl:Class	
GO:0001677	biolink:NamedThing	formation of translation initiation ternary complex	Formation of a complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2 (either eIF2 in eukaryotes, or IF2 in prokaryotes). In prokaryotes, fMet-tRNA (initiator) is used rather than Met-tRNA (initiator).	tmpzr1t_l9r_go_relaxed.owl	translation initiation ternary complex assembly													biological_process											owl:Class	
GO:0097200	biolink:NamedThing	cysteine-type endopeptidase activity involved in execution phase of apoptosis	Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile, and contributing to the execution phase of apoptosis.	tmpzr1t_l9r_go_relaxed.owl	effector caspase activity|executioner caspase activity					Examples of gene products that may be annotated to this term include CASP3, CASP6 and CASP7, also called effector (or executioner) caspases.		pr	2011-12-12T01:46:06Z					molecular_function											owl:Class	
GO:0003097	biolink:NamedThing	renal water transport	The directed movement of water (H2O) by the renal system.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0071585	biolink:NamedThing	detoxification of cadmium ion	Any process that reduces or removes the toxicity of cadmium ion. These may include transport of cadmium away from sensitive areas and to compartments or complexes whose purpose is sequestration of cadmium ion.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-01-28T03:38:48Z					biological_process											owl:Class	
GO:0003183	biolink:NamedThing	mitral valve morphogenesis	The process in which the structure of the mitral valve is generated and organized.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-10-08T12:02:01Z					biological_process											owl:Class	
GO:0003174	biolink:NamedThing	mitral valve development	The progression of the mitral valve over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-10-08T11:17:22Z					biological_process											owl:Class	
GO:0097222	biolink:NamedThing	mitochondrial mRNA polyadenylation	The enzymatic addition of a sequence of 40-60 adenylyl residues at the 3' end of a eukaryotic mitochondrial mRNA primary transcript. Mitochondria contain both stabilizing and destabilizing poly(A) tails.	tmpzr1t_l9r_go_relaxed.owl								pr	2012-01-24T02:47:19Z					biological_process											owl:Class	
GO:0001583	biolink:NamedThing	detection of chemical stimulus involved in sensory perception of salty taste	The series of events required for a salty taste stimulus to be received and converted to a molecular signal.	tmpzr1t_l9r_go_relaxed.owl	perception of salty taste, detection of chemical stimulus|perception of salty taste, sensory transduction of chemical stimulus|sensory transduction of chemical stimulus during perception of salty taste|salty taste detection|sensory detection of salty taste|sensory detection of chemical stimulus during perception of salty taste|sensory transduction of salty taste													biological_process											owl:Class	
GO:0050914	biolink:NamedThing	sensory perception of salty taste	The series of events required to receive a salty taste stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.	tmpzr1t_l9r_go_relaxed.owl	salty taste perception													biological_process											owl:Class	
GO:0061727	biolink:NamedThing	methylglyoxal catabolic process to lactate	The chemical reactions and pathways resulting in the breakdown of methylglyoxal, CH3-CO-CHO, into lactate.	tmpzr1t_l9r_go_relaxed.owl								dph	2015-07-21T17:25:57Z					biological_process											owl:Class	
GO:0031096	biolink:NamedThing	platelet dense tubular network lumen	The volume enclosed by the membranes of the platelet dense tubular network.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0031094	biolink:NamedThing	platelet dense tubular network	A network of membrane-bounded compartments found in blood platelets, where they regulate platelet activation by sequestering or releasing calcium. The dense tubular network exists as thin elongated membranes in resting platelets, and undergoes a major ultrastructural change, to a rounded vesicular form, upon addition of thrombin.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0061866	biolink:NamedThing	negative regulation of histone H3-S10 phosphorylation	Any process that stops, prevents, or reduces the frequency, rate or extent of the addition of one or more phosphate groups to histone H3 on a serine residue at position 10.	tmpzr1t_l9r_go_relaxed.owl								dph	2017-04-07T18:45:51Z					biological_process											owl:Class	
GO:0097314	biolink:NamedThing	apoptosome assembly	The aggregation, arrangement and bonding together of the apoptosome, a multisubunit protein complex involved in the signaling phase of the apoptotic process.	tmpzr1t_l9r_go_relaxed.owl	apoptosome formation							pr	2012-05-28T03:39:49Z					biological_process											owl:Class	
GO:0002875	biolink:NamedThing	negative regulation of chronic inflammatory response to antigenic stimulus	Any process that stops, prevents, or reduces the frequency, rate, or extent of a chronic inflammatory response to an antigenic stimulus.	tmpzr1t_l9r_go_relaxed.owl	inhibition of chronic inflammatory response to antigenic stimulus|downregulation of chronic inflammatory response to antigenic stimulus|down-regulation of chronic inflammatory response to antigenic stimulus|down regulation of chronic inflammatory response to antigenic stimulus													biological_process											owl:Class	
GO:0002439	biolink:NamedThing	chronic inflammatory response to antigenic stimulus	A chronic inflammatory response to an antigenic stimulus. A chronic inflammatory response persists indefinitely during days, weeks, or months in the life of an individual.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0000447	biolink:NamedThing	endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	Endonucleolytic cleavage between the SSU-rRNA and the 5.8S rRNA of an rRNA molecule originally produced as a tricistronic rRNA transcript that contained the Small SubUnit (SSU) rRNA, the 5.8S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript.	tmpzr1t_l9r_go_relaxed.owl	endonucleolytic cleavage at A2													biological_process											owl:Class	
GO:0036519	biolink:NamedThing	chemorepulsion of serotonergic neuron axon	The process in which a serotonergic neuron growth cone is directed to a specific target site in response to a repulsive chemical cue.	tmpzr1t_l9r_go_relaxed.owl	chemorepulsion of 5-HT axon|chemorepulsion of serotonergic axon							bf	2015-12-17T11:31:16Z					biological_process											owl:Class	
GO:0036515	biolink:NamedThing	serotonergic neuron axon guidance	The chemotaxis process that directs the migration of an axon growth cone of a serotonergic neuron to a specific target site in response to a combination of attractive and repulsive cues.	tmpzr1t_l9r_go_relaxed.owl	serotonergic axon guidance|5-HT axon guidance							bf	2015-12-17T11:15:54Z					biological_process											owl:Class	
GO:0010738	biolink:NamedThing	regulation of protein kinase A signaling	Any process that modulates the rate, frequency, or extent of protein kinase A signaling. PKA signaling is the series of reactions, mediated by the intracellular serine/threonine kinase protein kinase A, which occurs as a result of a single trigger reaction or compound.	tmpzr1t_l9r_go_relaxed.owl	regulation of protein kinase A signaling cascade|regulation of protein kinase A signalling cascade|regulation of PKA signaling cascade													biological_process											owl:Class	
GO:0010737	biolink:NamedThing	protein kinase A signaling	A series of reactions, mediated by the intracellular serine/threonine kinase protein kinase A, which occurs as a result of a single trigger reaction or compound.	tmpzr1t_l9r_go_relaxed.owl	PKA signaling cascade|protein kinase A signalling cascade|protein kinase A signal transduction|protein kinase A signaling cascade													biological_process											owl:Class	
GO:0060845	biolink:NamedThing	venous endothelial cell fate commitment	The commitment of a cell to a venous endothelial cell fate and its capacity to differentiate into an venous endothelial cell.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-08-12T10:51:23Z					biological_process											owl:Class	
GO:0005685	biolink:NamedThing	U1 snRNP	A ribonucleoprotein complex that contains small nuclear RNA U1, a heptameric ring of Sm proteins, as well as several proteins that are unique to the U1 snRNP, most of which remain associated with the U1 snRNA both while the U1 snRNP is free or assembled into a series of spliceosomal complexes.	tmpzr1t_l9r_go_relaxed.owl	snRNP U1													cellular_component											owl:Class	
GO:1900756	biolink:NamedThing	protein processing in phagocytic vesicle	Protein processing that takes place in the phagosome. Most protein processing in the phagosome represents protein degradation.	tmpzr1t_l9r_go_relaxed.owl	peptidolysis during protein maturation in phagosome|protein maturation by proteolysis in phagosome|protein processing in phagosome|protein maturation by peptide bond cleavage in phagosome|peptidolysis during protein maturation in phagocytic vesicle|protein maturation by proteolysis in phagocytic vesicle|protein maturation by peptide bond hydrolysis in phagosome|protein maturation by peptide bond hydrolysis in phagocytic vesicle|protein maturation by peptide bond cleavage in phagocytic vesicle							rjd	2012-05-29T09:55:14Z					biological_process											owl:Class	
GO:0006935	biolink:NamedThing	chemotaxis	The directed movement of a motile cell or organism, or the directed growth of a cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).	tmpzr1t_l9r_go_relaxed.owl	taxis in response to chemical stimulus				Wikipedia:Chemotaxis									biological_process											owl:Class	
GO:0033011	biolink:NamedThing	perinuclear theca	A condensed cytoplasmic structure that covers the nucleus of mammalian spermatozoa except for a narrow zone around the insertion of the tail. It shows two distinct regions, a subacrosomal layer and, continuing caudally beyond the acrosomic system, the postacrosomal sheath. The perinuclear theca has been considered a cytoskeletal scaffold responsible for maintaining the overall architecture of the mature sperm head; however, recent studies indicate that the bulk of its constituent proteins are not traditional cytoskeletal proteins but rather a variety of cytosolic proteins.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0106135	biolink:NamedThing	negative regulation of cardiac muscle cell contraction	Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle cell contraction.	tmpzr1t_l9r_go_relaxed.owl								hjd	2018-07-26T16:10:17Z					biological_process											owl:Class	
GO:0086003	biolink:NamedThing	cardiac muscle cell contraction	The actin filament-based process in which cytoplasmic actin filaments slide past one another resulting in contraction of a cardiac muscle cell.	tmpzr1t_l9r_go_relaxed.owl								tb	2011-11-10T07:48:15Z					biological_process											owl:Class	
GO:0061444	biolink:NamedThing	endocardial cushion cell development	The process whose specific outcome is the progression of an endocardial cushion cell over time, from its formation to the mature state.	tmpzr1t_l9r_go_relaxed.owl								dph	2012-03-13T09:07:46Z					biological_process											owl:Class	
GO:0061443	biolink:NamedThing	endocardial cushion cell differentiation	The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of an endocardial cushion cell.	tmpzr1t_l9r_go_relaxed.owl								dph	2012-03-13T09:05:38Z					biological_process											owl:Class	
GO:1905073	biolink:NamedThing	regulation of tight junction disassembly	Any process that modulates the frequency, rate or extent of tight junction disassembly.	tmpzr1t_l9r_go_relaxed.owl	regulation of occluding cell junction disassembly|regulation of occluding junction disassembly							rl	2016-03-23T19:32:51Z					biological_process											owl:Class	
GO:1905071	biolink:NamedThing	tight junction disassembly	The disaggregation of an tight junction into its constituent components.	tmpzr1t_l9r_go_relaxed.owl	occluding junction disassembly|occluding cell junction disassembly							rl	2016-03-23T12:35:08Z					biological_process											owl:Class	
GO:0010197	biolink:NamedThing	polar nucleus fusion	The merging of the polar nuclei, the two nuclei contained within the same cell that are created from the mitotic division of the megaspore during angiosperm reproduction. Polar nuclear fusion takes place in the ovule, forming in the fusion nucleus and giving rise to the endosperm when fertilized.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0009559	biolink:NamedThing	embryo sac central cell differentiation	The process in which the two uncellularized polar nuclei cellularize, fuse and acquire the specialized features of a mononucleate diploid central cell.	tmpzr1t_l9r_go_relaxed.owl	embryo sac endosperm mother cell differentiation|female gametophyte central cell differentiation													biological_process											owl:Class	
GO:1901145	biolink:NamedThing	mesenchymal cell apoptotic process involved in nephron morphogenesis	Any mesenchymal cell apoptotic process that is involved in nephron morphogenesis.	tmpzr1t_l9r_go_relaxed.owl								pr	2012-07-13T01:43:51Z					biological_process											owl:Class	
GO:2000492	biolink:NamedThing	regulation of interleukin-18-mediated signaling pathway	Any process that modulates the frequency, rate or extent of interleukin-18-mediated signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	regulation of interleukin-18-mediated signalling pathway							pr	2011-03-16T01:59:18Z					biological_process											owl:Class	
GO:0035655	biolink:NamedThing	interleukin-18-mediated signaling pathway	A series of molecular signals initiated by the binding of interleukin-18 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.	tmpzr1t_l9r_go_relaxed.owl	interleukin-18-mediated signalling pathway							bf	2011-01-26T09:55:57Z					biological_process											owl:Class	
GO:0070422	biolink:NamedThing	G-protein beta/gamma-Raf-1 complex	A protein complex formed by the association of the serine-threonine protein kinase Raf-1 with the beta and gamma subunits of a heterotrimeric G protein.	tmpzr1t_l9r_go_relaxed.owl	G protein complex (GNG2, GNB2L1, RAF1)					See also the cellular component term 'heterotrimeric G-protein complex ; GO:0005834'.								cellular_component											owl:Class	
GO:1902675	biolink:NamedThing	left ventral basal body	Any ciliary basal body that is part of a left ventral flagellum found in Giardia species (trophozoite stage).	tmpzr1t_l9r_go_relaxed.owl	ciliary basal body of left ventral cilium|cilial basal body of left ventral cilium|cilium basal body of left ventral flagellum|microtubule basal body of left ventral flagellum|cilium basal body of left ventral cilium|left ventral flagellum ciliary basal body|microtubule basal body of left ventral cilium|cilial basal body of left ventral flagellum|ciliary basal body of left ventral flagellum					Note that we deem cilium and microtubule-based flagellum to be equivalent. Also note that, due to the asymmetric nature of the Giardia trophozoite, this term is defined spatially as the trophozoite is viewed from the dorsal side, with the two nuclei dorsal to the ventral disc, and the ventral disc toward the anterior.		pr	2014-02-05T14:54:54Z					cellular_component											owl:Class	
GO:0003187	biolink:NamedThing	ventriculo bulbo valve morphogenesis	The process in which the structure of the ventriculo bulbo valve is generated and organized.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-10-08T12:07:00Z					biological_process											owl:Class	
GO:0003173	biolink:NamedThing	ventriculo bulbo valve development	The progression of the ventriculo bulbo valve over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-10-08T11:16:25Z					biological_process											owl:Class	
GO:0070550	biolink:NamedThing	rDNA condensation	The process in which the chromatin structure of the rDNA repeats is compacted. In S. cerevisiae, condensation and resolution of the rDNA occurs during anaphase.	tmpzr1t_l9r_go_relaxed.owl	rDNA packaging													biological_process											owl:Class	
GO:1990700	biolink:NamedThing	nucleolar chromatin organization	Any process that results in the specification, formation or maintenance of the physical structure of nucleolar chromatin.	tmpzr1t_l9r_go_relaxed.owl	establishment or maintenance of nucleolar chromatin architecture|nucleolar chromatin organisation							mah	2015-03-16T12:11:01Z					biological_process											owl:Class	
GO:0016070	biolink:NamedThing	RNA metabolic process	The cellular chemical reactions and pathways involving RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage.	tmpzr1t_l9r_go_relaxed.owl	RNA metabolism													biological_process											owl:Class	
GO:0021854	biolink:NamedThing	hypothalamus development	The progression of the hypothalamus region of the forebrain, from its initial formation to its mature state.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1905475	biolink:NamedThing	regulation of protein localization to membrane	Any process that modulates the frequency, rate or extent of protein localization to membrane.	tmpzr1t_l9r_go_relaxed.owl	regulation of protein localisation in membrane|regulation of protein localization in membrane							bc	2016-09-21T16:20:03Z					biological_process											owl:Class	
GO:0032911	biolink:NamedThing	negative regulation of transforming growth factor beta1 production	Any process that stops, prevents, or reduces the frequency, rate, or extent of production of transforming growth factor-beta1.	tmpzr1t_l9r_go_relaxed.owl	downregulation of transforming growth factor-beta1 production|negative regulation of transforming growth factor-beta1 production|negative regulation of TGF-B1 production|negative regulation of TGFB1 production|inhibition of transforming growth factor-beta1 production|down regulation of transforming growth factor-beta1 production|down-regulation of transforming growth factor-beta1 production													biological_process											owl:Class	
GO:0032905	biolink:NamedThing	transforming growth factor beta1 production	The appearance of transforming growth factor-beta1 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	tmpzr1t_l9r_go_relaxed.owl	transforming growth factor-beta1 production|TGF-B1 production|TGFB1 production													biological_process											owl:Class	
GO:0060841	biolink:NamedThing	venous blood vessel development	The progression of the venous blood vessel over time from its initial formation to the mature structure. Venous blood vessels carry blood back to the heart after the capillary bed.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-08-12T10:14:07Z					biological_process											owl:Class	
GO:0031016	biolink:NamedThing	pancreas development	The process whose specific outcome is the progression of the pancreas over time, from its formation to the mature structure. The pancreas is an endoderm derived structure that produces precursors of digestive enzymes and blood glucose regulating enzymes.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Pancreas									biological_process											owl:Class	
GO:1903969	biolink:NamedThing	regulation of response to macrophage colony-stimulating factor	Any process that modulates the frequency, rate or extent of response to macrophage colony-stimulating factor.	tmpzr1t_l9r_go_relaxed.owl	regulation of response to macrophage colony-stimulating factor stimulus|regulation of response to M-CSF							nc	2015-03-02T14:41:02Z					biological_process											owl:Class	
GO:0071959	biolink:NamedThing	maintenance of mitotic sister chromatid cohesion, arms	The process in which the association between sister chromatids of a replicated chromosome along the length of the chromosome arms, is maintained as chromosomes condense, attach to the spindle in a bipolar orientation, and congress to the metaphase plate during a mitotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl	maintenance of sister chromatin cohesion along arms at mitosis|maintenance of mitotic sister chromatin cohesion along arms							mah	2011-06-01T04:08:43Z					biological_process											owl:Class	
GO:0071961	biolink:NamedThing	mitotic sister chromatid cohesion, arms	The cell cycle process in which the sister chromatids of a replicated chromosome are joined along the length of the chromosome arms during mitosis.	tmpzr1t_l9r_go_relaxed.owl	sister chromatid cohesion along arms at mitosis|mitotic sister chromatid cohesion along arms							mah	2011-06-02T11:21:13Z					biological_process											owl:Class	
GO:0032043	biolink:NamedThing	mitochondrial DNA catabolic process	The chemical reactions and pathways resulting in the breakdown of mitochondrial DNA.	tmpzr1t_l9r_go_relaxed.owl	mitochondrial DNA breakdown|mtDNA catabolism|mitochondrial DNA degradation|mtDNA breakdown|mtDNA catabolic process|mitochondrial DNA catabolism|mtDNA degradation													biological_process											owl:Class	
GO:1903910	biolink:NamedThing	negative regulation of receptor clustering	Any process that stops, prevents or reduces the frequency, rate or extent of receptor clustering.	tmpzr1t_l9r_go_relaxed.owl	downregulation of receptor clustering|down-regulation of receptor clustering|inhibition of receptor clustering|down regulation of receptor clustering							als	2015-02-09T10:56:42Z					biological_process											owl:Class	
GO:0042405	biolink:NamedThing	nuclear inclusion body	An intranuclear focus at which aggregated proteins have been sequestered.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0031573	biolink:NamedThing	mitotic intra-S DNA damage checkpoint signaling	A mitotic cell cycle checkpoint that slows DNA synthesis in response to DNA damage by the prevention of new origin firing and the stabilization of slow replication fork progression.	tmpzr1t_l9r_go_relaxed.owl	signal transduction involved in intra-S DNA damage checkpoint|S-phase checkpoint|mitotic intra-S DNA damage checkpoint|intra-S DNA damage checkpoint	https://github.com/geneontology/go-ontology/issues/20935										GO:0072428		biological_process											owl:Class	
GO:0000084	biolink:NamedThing	mitotic S phase	The cell cycle phase, following G1, during which DNA synthesis takes place as part of a mitotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl	S phase of mitotic cell cycle|S-phase of mitotic cell cycle					Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).								biological_process											owl:Class	
GO:1902676	biolink:NamedThing	right ventral basal body	Any ciliary basal body that is part of a right ventral flagellum found in Giardia species (trophozoite stage).	tmpzr1t_l9r_go_relaxed.owl	right ventral flagellum ciliary basal body|cilium basal body of right ventral flagellum|cilium basal body of right ventral cilium|cilial basal body of right ventral flagellum|ciliary basal body of right ventral flagellum|ciliary basal body of right ventral cilium|microtubule basal body of right ventral flagellum|cilial basal body of right ventral cilium|microtubule basal body of right ventral cilium					Note that we deem cilium and microtubule-based flagellum to be equivalent. Also note that, due to the asymmetric nature of the Giardia trophozoite, this term is defined spatially as the trophozoite is viewed from the dorsal side, with the two nuclei dorsal to the ventral disc, and the ventral disc toward the anterior.		pr	2014-02-05T14:58:13Z					cellular_component											owl:Class	
GO:0097559	biolink:NamedThing	right ventral flagellum	A cilium (also called flagellum) found in Giardia species (trophozoite stage). It is nucleated by the right ventral basal body and exits the cell body proximally and dorsal to the ventral disc.	tmpzr1t_l9r_go_relaxed.owl	right ventral cilium					Note that we deem cilium and microtubule-based flagellum to be equivalent; the primary term name reflects frequency of use. Also note that, due to the asymmetric nature of the Giardia trophozoite, this term is defined spatially as the trophozoite is viewed from the dorsal side, with the two nuclei dorsal to the ventral disc, and the ventral disc toward the anterior.		pr	2014-02-05T13:28:20Z					cellular_component											owl:Class	
GO:0060350	biolink:NamedThing	endochondral bone morphogenesis	The process in which bones are generated and organized as a result of the conversion of initial cartilaginous anlage into bone.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0060671	biolink:NamedThing	epithelial cell differentiation involved in embryonic placenta development	The process in which a trophoblast cell acquires specialized features of an epithelial cell of the placental labyrinthine layer.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-06-02T11:40:52Z					biological_process											owl:Class	
GO:0098831	biolink:NamedThing	presynaptic active zone cytoplasmic component	A specialized region below the presynaptic membrane, characterized by electron-dense material, a specialized cytoskeletal matrix and accumulated (associated) synaptic vesicles.	tmpzr1t_l9r_go_relaxed.owl	presynaptic zone cortex|cortex of presynaptic active zone													cellular_component											owl:Class	
GO:0048786	biolink:NamedThing	presynaptic active zone	A specialized region of the plasma membrane and cell cortex of a presynaptic neuron; encompasses a region of the plasma membrane where synaptic vesicles dock and fuse, and a specialized cortical cytoskeletal matrix.	tmpzr1t_l9r_go_relaxed.owl	pre-synaptic active zone|presynaptic specialization|pre-synaptic active zone component				NIF_Subcellular:sao792027222									cellular_component											owl:Class	
GO:0021711	biolink:NamedThing	cerebellar unipolar brush cell differentiation	The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature unipolar brush cell in the cerebellum. Differentiation includes the processes involved in commitment of a neuroblast to a unipolar brush cell fate. A unipolar brush cell is a glutamatergic interneuron found in the cerebellar cortex.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:2000821	biolink:NamedThing	regulation of grooming behavior	Any process that modulates the frequency, rate or extent of grooming behavior.	tmpzr1t_l9r_go_relaxed.owl	regulation of grooming behaviour							rl	2011-07-14T04:48:12Z					biological_process											owl:Class	
GO:0007625	biolink:NamedThing	grooming behavior	The specific behavior of an organism relating to grooming, cleaning and brushing to remove dirt and parasites.	tmpzr1t_l9r_go_relaxed.owl	grooming behaviour													biological_process											owl:Class	
GO:2000721	biolink:NamedThing	positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation	Any positive regulation of transcription from RNA polymerase II promoter that is involved in smooth muscle cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of global transcription from Pol II promoter of smooth muscle cell differentiation|positive regulation of transcription from RNA polymerase II promoter, global of nonstriated muscle cell differentiation|activation of transcription from RNA polymerase II promoter of nonstriated muscle cell differentiation|positive regulation of transcription from RNA polymerase II promoter of nonstriated muscle cell differentiation|positive regulation of global transcription from Pol II promoter of nonstriated muscle cell differentiation|positive regulation of transcription from Pol II promoter of nonstriated muscle cell differentiation|stimulation of global transcription from RNA polymerase II promoter of smooth muscle cell differentiation|up-regulation of global transcription from RNA polymerase II promoter of smooth muscle cell differentiation|up-regulation of global transcription from RNA polymerase II promoter of nonstriated muscle cell differentiation|up regulation of global transcription from RNA polymerase II promoter of smooth muscle cell differentiation|positive regulation of transcription from RNA polymerase II promoter, global of smooth muscle cell differentiation|activation of global transcription from RNA polymerase II promoter of nonstriated muscle cell differentiation|up regulation of global transcription from RNA polymerase II promoter of nonstriated muscle cell differentiation|up regulation of transcription from RNA polymerase II promoter of smooth muscle cell differentiation|stimulation of transcription from RNA polymerase II promoter of smooth muscle cell differentiation|stimulation of global transcription from RNA polymerase II promoter of nonstriated muscle cell differentiation|positive regulation of transcription from Pol II promoter of smooth muscle cell differentiation|upregulation of global transcription from RNA polymerase II promoter of smooth muscle cell differentiation|up regulation of transcription from RNA polymerase II promoter of nonstriated muscle cell differentiation|upregulation of global transcription from RNA polymerase II promoter of nonstriated muscle cell differentiation|positive regulation of gene-specific transcription from RNA polymerase II promoter of smooth muscle cell differentiation|up-regulation of transcription from RNA polymerase II promoter of smooth muscle cell differentiation|stimulation of transcription from RNA polymerase II promoter of nonstriated muscle cell differentiation|activation of transcription from RNA polymerase II promoter of smooth muscle cell differentiation|positive regulation of transcription from RNA polymerase II promoter of smooth muscle cell differentiation|activation of global transcription from RNA polymerase II promoter of smooth muscle cell differentiation|up-regulation of transcription from RNA polymerase II promoter of nonstriated muscle cell differentiation|positive regulation of gene-specific transcription from RNA polymerase II promoter of nonstriated muscle cell differentiation							vk	2011-06-08T08:34:55Z					biological_process											owl:Class	
GO:0002723	biolink:NamedThing	positive regulation of B cell cytokine production	Any process that activates or increases the frequency, rate, or extent of B cell cytokine production.	tmpzr1t_l9r_go_relaxed.owl	activation of B cell cytokine production|positive regulation of B lymphocyte cytokine production|positive regulation of B-lymphocyte cytokine production|stimulation of B cell cytokine production|up-regulation of B cell cytokine production|positive regulation of B-cell cytokine production|up regulation of B cell cytokine production|upregulation of B cell cytokine production													biological_process											owl:Class	
GO:0002368	biolink:NamedThing	B cell cytokine production	Any process that contributes to cytokine production by a B cell.	tmpzr1t_l9r_go_relaxed.owl	B lymphocyte cytokine production|B-lymphocyte cytokine production|B-cell cytokine production					Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.								biological_process											owl:Class	
GO:0072262	biolink:NamedThing	metanephric glomerular mesangial cell proliferation involved in metanephros development	The multiplication or reproduction of glomerular mesangial cells in the metanephros, resulting in the expansion of the population.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-03-30T02:27:27Z					biological_process											owl:Class	
GO:0015164	biolink:NamedThing	glucuronoside transmembrane transporter activity	Enables the transfer of a glucuronosides from one side of a membrane to the other. Glucuronosides are any compound formed by combination of glycosidic linkage of a hydroxy compound (e.g. an alcohol or a saccharide) with the anomeric carbon atom of glucuronate.	tmpzr1t_l9r_go_relaxed.owl	glucuronide transporter activity													molecular_function											owl:Class	
GO:0015779	biolink:NamedThing	glucuronoside transport	The directed movement of glucuronosides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Glucuronosides are any compound formed by combination of glycosidic linkage of a hydroxy compound (e.g. an alcohol or a saccharide) with the anomeric carbon atom of glucuronate.	tmpzr1t_l9r_go_relaxed.owl	glucuronide transport													biological_process											owl:Class	
GO:0072678	biolink:NamedThing	T cell migration	The movement of a T cell within or between different tissues and organs of the body.	tmpzr1t_l9r_go_relaxed.owl	T-lymphocyte migration|T lymphocyte migration|T-cell migration							mah	2011-02-22T03:40:40Z					biological_process											owl:Class	
GO:0005993	biolink:NamedThing	trehalose catabolic process	The chemical reactions and pathways resulting in the breakdown of trehalose, a disaccharide isomeric with sucrose and obtained from certain lichens and fungi.	tmpzr1t_l9r_go_relaxed.owl	mycose catabolic process|mycose catabolism|trehalose catabolism|trehalose degradation|mykose catabolic process|mykose catabolism|trehalose breakdown				MetaCyc:TREDEGLOW-PWY									biological_process											owl:Class	
GO:0008627	biolink:NamedThing	intrinsic apoptotic signaling pathway in response to osmotic stress	A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced in response to changes in intracellular ion homeostasis, and ends when the execution phase of apoptosis is triggered.	tmpzr1t_l9r_go_relaxed.owl	induction of apoptosis by ionic changes													biological_process											owl:Class	
GO:0048935	biolink:NamedThing	peripheral nervous system neuron development	The process whose specific outcome is the progression of a neuron whose cell body is located in the peripheral nervous system, from initial commitment of the cell to a neuronal fate, to the fully functional differentiated neuron.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0048934	biolink:NamedThing	peripheral nervous system neuron differentiation	The process in which a relatively unspecialized cell acquires specialized features of a neuron whose cell body resides in the peripheral nervous system.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0098039	biolink:NamedThing	replicative transposition, DNA-mediated	Process of transposition in which the existing element is replicated and one of the copies is excised and integrated at a new target site. Also referred to as copy-and-paste transposition.	tmpzr1t_l9r_go_relaxed.owl	copy-and-paste transposition|transpositional DNA genome replication							bm	2012-07-20T16:52:02Z					biological_process											owl:Class	
GO:0006973	biolink:NamedThing	intracellular accumulation of glycerol	The accumulation of glycerol within a cell, for example by increased glycerol biosynthesis combined with decreased permeability of the cell membrane to glycerol, in response to the detection of a hyperosmotic environment.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0071474	biolink:NamedThing	cellular hyperosmotic response	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a hyperosmotic environment, i.e. an environment with a higher concentration of solutes than the organism or cell.	tmpzr1t_l9r_go_relaxed.owl	cellular HOG response|cellular hypertonic response|cellular response to hypertonicity							mah	2009-12-18T11:51:36Z					biological_process											owl:Class	
GO:0008649	biolink:NamedThing	rRNA methyltransferase activity	Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a nucleoside residue in an rRNA molecule.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0031167	biolink:NamedThing	rRNA methylation	The posttranscriptional addition of methyl groups to specific residues in an rRNA molecule.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0000278	biolink:NamedThing	mitotic cell cycle	Progression through the phases of the mitotic cell cycle, the most common eukaryotic cell cycle, which canonically comprises four successive phases called G1, S, G2, and M and includes replication of the genome and the subsequent segregation of chromosomes into daughter cells. In some variant cell cycles nuclear replication or nuclear division may not be followed by cell division, or G1 and G2 phases may be absent.	tmpzr1t_l9r_go_relaxed.owl	mitosis				Wikipedia:Mitosis	Note that this term should not be confused with 'GO:0140014 ; mitotic nuclear division'. 'GO:0000278 ; mitotic cell cycle represents the entire mitotic cell cycle, while 'GO:0140014 ; mitotic nuclear division' specifically represents the actual nuclear division step of the mitotic cell cycle.						GO:0007067		biological_process											owl:Class	
GO:0003274	biolink:NamedThing	endocardial cushion fusion	The cell-cell adhesion process of mesenchymal cardiac cushion cells that contributes to the process of cushion shaping.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-10-20T09:26:32Z					biological_process											owl:Class	
GO:0003203	biolink:NamedThing	endocardial cushion morphogenesis	The process in which the anatomical structure of the endocardial cushion is generated and organized. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-10-08T01:43:22Z					biological_process											owl:Class	
GO:0038056	biolink:NamedThing	negative regulation of BMP signaling pathway by negative regulation of BMP secretion	Any process that stops, prevents, or reduces the frequency, rate or extent of the BMP signaling pathway by stopping, preventing or reducing the frequency, rate or extent of secretion of a member of the BMP family of proteins from the signaling cell.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of BMP signaling pathway by negative regulation of bone morphogenetic protein secretion|negative regulation of BMP signalling pathway by negative regulation of BMP secretion							bf	2011-12-19T10:55:47Z					biological_process											owl:Class	
GO:0038055	biolink:NamedThing	BMP secretion	The controlled release of a member of the BMP family of proteins from a cell.	tmpzr1t_l9r_go_relaxed.owl	BMP protein secretion|bone morphogenetic protein secretion							bf	2011-12-14T02:31:39Z					biological_process											owl:Class	
GO:0015607	biolink:NamedThing	ABC-type fatty-acyl-CoA transporter activity	Catalysis of the reaction ATP + H(2)O + fatty acyl CoA(Side 1) <=> ADP + phosphate + fatty acyl CoA(Side 2). A fatty acyl CoA group is any acyl group derived from a fatty acid with a coenzyme A group attached to it.	tmpzr1t_l9r_go_relaxed.owl	fatty acyl CoA transporter activity|ABC-type fatty-acyl-CoA transporter|ATPase-coupled fatty-acyl-CoA transmembrane transporter activity|fatty-acyl-CoA-transporting ATPase|fatty-acyl-CoA transmembrane transporter activity				EC:7.6.2.4|RHEA:15181									molecular_function											owl:Class	
GO:0031612	biolink:NamedThing	cytosolic proteasome regulatory particle, base subcomplex	The subcomplex of the proteasome regulatory particle that directly associates with the proteasome core complex located in the cytosol of the cell.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0031600	biolink:NamedThing	cytosolic proteasome regulatory particle	A multisubunit complex located in the cytosol of a cell, which caps one or both ends of the proteasome core complex. This complex recognizes, unfolds ubiquitinated proteins and translocates them to the proteasome core complex.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0050321	biolink:NamedThing	tau-protein kinase activity	Catalysis of the reaction: ATP + tau-protein = ADP + O-phospho-tau-protein.	tmpzr1t_l9r_go_relaxed.owl	TPK|TTK|[Tau protein] kinase activity|glycogen synthase kinase-3beta activity|protein tau kinase activity|ATP:tau-protein O-phosphotransferase activity|GSK|tau kinase activity|tau protein kinase activity|STK31|tau-protein kinase I activity|cdk5/p20|tau-tubulin kinase activity|TPK I|TPK II|CDK5/p23|brain protein kinase PK40erk activity|tau-protein kinase II activity				MetaCyc:TAU-PROTEIN-KINASE-RXN|EC:2.7.11.26									molecular_function											owl:Class	
GO:1903679	biolink:NamedThing	positive regulation of cap-independent translational initiation	Any process that activates or increases the frequency, rate or extent of cap-independent translational initiation.	tmpzr1t_l9r_go_relaxed.owl	up regulation of cap-independent translational initiation|up-regulation of cap-independent translational initiation|upregulation of cap-independent translational initiation|activation of cap-independent translational initiation							bf	2014-11-27T19:52:36Z					biological_process											owl:Class	
GO:0002190	biolink:NamedThing	cap-independent translational initiation	The process where translation initiation recruits the 40S ribosomal subunits in a Cap and 5' end independent fashion before an AUG codon is encountered in an appropriate sequence context to initiate mRNA or circRNA translation.	tmpzr1t_l9r_go_relaxed.owl								hjd	2011-08-11T02:16:05Z					biological_process											owl:Class	
GO:0000713	biolink:NamedThing	meiotic heteroduplex formation	During meiosis, the formation of a stable duplex DNA that contains one strand from each of the two recombining DNA molecules.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0006310	biolink:NamedThing	DNA recombination	Any process in which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents. In eukaryotes genetic recombination can occur by chromosome assortment, intrachromosomal recombination, or nonreciprocal interchromosomal recombination. Interchromosomal recombination occurs by crossing over. In bacteria it may occur by genetic transformation, conjugation, transduction, or F-duction.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0090254	biolink:NamedThing	cell elongation involved in imaginal disc-derived wing morphogenesis	The process in which a cell elongates and contributes to imaginal disc-derived wing morphogenesis.	tmpzr1t_l9r_go_relaxed.owl								tb	2010-01-22T11:40:46Z					biological_process											owl:Class	
GO:0030089	biolink:NamedThing	phycobilisome	Any of the granules, approximately 32 nm x 48 nm and consisting of highly aggregated phycobiliproteins, that are attached in arrays to the external face of a thylakoid membrane in algae of the phyla Cyanophyta and Rhodophyta, where they function as light-harvesting devices in photosynthesis. Excitation energy in the phycobilisome flows in the sequence: phycoerythrin, phycocyanin, allophycocyanin before passing to the antenna chlorophyll of photosystem II.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Phycobilisome									cellular_component											owl:Class	
GO:0002138	biolink:NamedThing	retinoic acid biosynthetic process	The chemical reactions and pathways resulting in the biosynthesis of retinoic acid, one of the three components that makes up vitamin A.	tmpzr1t_l9r_go_relaxed.owl	retinoic acid anabolic process							hjd	2009-05-01T10:53:24Z					biological_process											owl:Class	
GO:1904354	biolink:NamedThing	negative regulation of telomere capping	Any process that stops, prevents or reduces the frequency, rate or extent of telomere capping.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of telomere end protection|down-regulation of telomere capping|downregulation of telomere end protection|inhibition of telomere end protection|down regulation of telomere end protection|down regulation of telomere capping|inhibition of telomere capping|down-regulation of telomere end protection|downregulation of telomere capping							nc	2015-06-12T16:51:14Z					biological_process											owl:Class	
GO:0016233	biolink:NamedThing	telomere capping	A process in which telomeres are protected from degradation and fusion, thereby ensuring chromosome stability by protecting the ends from both degradation and from being recognized as damaged DNA. May be mediated by specific single- or double-stranded telomeric DNA binding proteins.	tmpzr1t_l9r_go_relaxed.owl	telomere end protection													biological_process											owl:Class	
GO:1900091	biolink:NamedThing	regulation of raffinose biosynthetic process	Any process that modulates the frequency, rate or extent of raffinose biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of raffinose biosynthesis|regulation of raffinose formation|regulation of raffinose synthesis|regulation of raffinose anabolism							dhl	2012-02-08T06:31:54Z					biological_process											owl:Class	
GO:0033529	biolink:NamedThing	raffinose biosynthetic process	The chemical reactions and pathways resulting in the formation of raffinose, the trisaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside.	tmpzr1t_l9r_go_relaxed.owl	raffinose formation|raffinose synthesis|raffinose anabolism|raffinose biosynthesis													biological_process											owl:Class	
GO:0061285	biolink:NamedThing	mesonephric capsule development	The progression of the mesonephric capsule over time, from its formation to the mature structure. The mesonephric capsule is the tough fibrous layer surrounding the mesonephros, covered in a thick layer of perinephric adipose tissue.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-09-02T01:50:06Z					biological_process											owl:Class	
GO:0001823	biolink:NamedThing	mesonephros development	The process whose specific outcome is the progression of the mesonephros over time, from its formation to the mature structure. In mammals, the mesonephros is the second of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the mesonephros will form the mature kidney.	tmpzr1t_l9r_go_relaxed.owl	Wolffian body development													biological_process											owl:Class	
GO:0061343	biolink:NamedThing	cell adhesion involved in heart morphogenesis	The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules that contributes to the shaping of the heart.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-09-29T11:34:06Z					biological_process											owl:Class	
GO:0003007	biolink:NamedThing	heart morphogenesis	The developmental process in which the heart is generated and organized. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.	tmpzr1t_l9r_go_relaxed.owl	cardiac morphogenesis													biological_process											owl:Class	
GO:1905909	biolink:NamedThing	regulation of dauer entry	Any process that modulates the frequency, rate or extent of dauer entry.	tmpzr1t_l9r_go_relaxed.owl	regulation of nematode entry into dormancy							hbye	2017-02-06T15:34:01Z					biological_process											owl:Class	
GO:0043053	biolink:NamedThing	dauer entry	Entry into the facultative diapause of the dauer (enduring) larval stage of nematode development.	tmpzr1t_l9r_go_relaxed.owl	nematode entry into dormancy													biological_process											owl:Class	
GO:2001033	biolink:NamedThing	negative regulation of double-strand break repair via nonhomologous end joining	Any process that stops, prevents or reduces the frequency, rate or extent of double-strand break repair via nonhomologous end joining.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of NHEJ							yaf	2011-08-24T09:25:46Z					biological_process											owl:Class	
GO:2000604	biolink:NamedThing	negative regulation of secondary growth	Any process that stops, prevents or reduces the frequency, rate or extent of secondary growth.	tmpzr1t_l9r_go_relaxed.owl								tb	2011-04-15T10:30:47Z					biological_process											owl:Class	
GO:0080117	biolink:NamedThing	secondary growth	Lateral growth of a plant axis (shoot axis or root) that is an increase in thickness resulting from formation of secondary vascular tissues by the vascular cambium.	tmpzr1t_l9r_go_relaxed.owl	cambial secondary growth					Occurs in vascular plants, including gymnosperms and most dicotyledons. Commonly supplemented by activity of the cork cambium or phellogen (PO:0005599). Monocotyledons do not have secondary growth, but may undergo primary thickening (GO:0080192) or secondary thickening (GO:0080191), which can give the appearance of secondary growth. Primary and secondary growth can occur simultaneously in the same organism.		dhl	2009-04-27T03:36:28Z					biological_process											owl:Class	
GO:1900238	biolink:NamedThing	regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway	Any process that modulates the frequency, rate or extent of regulation of metanephric mesenchymal cell migration, by platelet-derived growth factor receptor-beta signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	regulation of metanephric mesenchyme chemotaxis by platelet-derived growth factor receptor-beta signaling pathway|regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signalling pathway							yaf	2012-03-27T03:33:56Z					biological_process											owl:Class	
GO:0035789	biolink:NamedThing	metanephric mesenchymal cell migration	The orderly movement of undifferentiated metanephric mesenchymal cells (precursors to metanephric mesangial cells) from the mesenchyme into the cleft of the developing glomerulus, during development of the metanephros.	tmpzr1t_l9r_go_relaxed.owl	metanephric mesenchyme chemotaxis							bf	2011-04-06T10:45:15Z					biological_process											owl:Class	
GO:1990053	biolink:NamedThing	DNA-5-methylcytosine glycosylase activity	Catalysis of the reaction: DNA containing 5-methylcytosine + H2O = DNA with abasic site + 5-methylcytosine. This reaction is the hydrolysis of DNA by cleavage of the N-C1' glycosidic bond between the DNA 5-methylcytosine and the deoxyribose sugar to remove the 5-methylcytosine, leaving an abasic site.	tmpzr1t_l9r_go_relaxed.owl								tb	2013-02-22T01:09:06Z					molecular_function											owl:Class	
GO:0021943	biolink:NamedThing	formation of radial glial scaffolds	The formation of scaffolds from a radial glial cell. The scaffolds are used as a substrate for the radial migration of cells.	tmpzr1t_l9r_go_relaxed.owl	Bergmann fiber formation|Bergmann fiber biosynthesis													biological_process											owl:Class	
GO:0031569	biolink:NamedThing	mitotic G2 cell size control checkpoint signaling	A signal transduction process that contributes to a cell size control checkpoint prior to the G2/M transition of mitosis.	tmpzr1t_l9r_go_relaxed.owl	mitotic cell cycle G2/M transition size control checkpoint|G2 cell size control checkpoint|signal transduction involved in mitotic cell cycle G2/M transition size control checkpoint|mitotic G2 cell size control checkpoint|signal transduction involved in G2/M transition size control checkpoint|signal transduction involved in G2 cell size control checkpoint|G2/M transition size control checkpoint	https://github.com/geneontology/go-ontology/issues/20935										GO:0072453		biological_process											owl:Class	
GO:0051319	biolink:NamedThing	G2 phase	The cell cycle 'gap' phase which is the interval between the completion of DNA synthesis and the beginning of DNA segregation (usually by mitosis or meiosis).	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:G2_phase	Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).								biological_process											owl:Class	
GO:1990422	biolink:NamedThing	glyoxalase (glycolic acid-forming) activity	Catalysis of the reaction: glyoxal + H2O = glycolic acid. Catalysis occurs in the absence of a cofactor.	tmpzr1t_l9r_go_relaxed.owl								bf	2014-07-21T09:00:21Z					molecular_function											owl:Class	
GO:1903190	biolink:NamedThing	glyoxal catabolic process	The chemical reactions and pathways resulting in the breakdown of glyoxal.	tmpzr1t_l9r_go_relaxed.owl	glyoxal degradation|glyoxal breakdown|glyoxal catabolism							bf	2014-07-15T10:11:51Z					biological_process											owl:Class	
GO:0001881	biolink:NamedThing	receptor recycling	The process that results in the return of receptor molecules to an active state and an active cellular location after they have been stimulated by a ligand. An active state is when the receptor is ready to receive a signal.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0006897	biolink:NamedThing	endocytosis	A vesicle-mediated transport process in which cells take up external materials or membrane constituents by the invagination of a small region of the plasma membrane to form a new membrane-bounded vesicle.	tmpzr1t_l9r_go_relaxed.owl	nonselective vesicle endocytosis|endocytic import into cell|vesicle endocytosis|plasma membrane invagination				Wikipedia:Endocytosis							GO:0016196|GO:0016193|GO:0098701		biological_process											owl:Class	
GO:1901726	biolink:NamedThing	negative regulation of histone deacetylase activity	Any process that stops, prevents or reduces the frequency, rate or extent of histone deacetylase activity.	tmpzr1t_l9r_go_relaxed.owl	downregulation of histone deacetylase activity|down-regulation of histone deacetylase activity|inhibition of histone deacetylase activity|down regulation of histone deacetylase activity							rl	2013-01-07T09:14:17Z					biological_process											owl:Class	
GO:1901421	biolink:NamedThing	positive regulation of response to alcohol	Any process that activates or increases the frequency, rate or extent of response to alcohol.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of response to alcohol|up regulation of response to alcohol|upregulation of response to alcohol|activation of response to alcohol							tt	2012-10-01T16:53:42Z					biological_process											owl:Class	
GO:0035844	biolink:NamedThing	cloaca development	The process whose specific outcome is the progression of the cloaca over time, from it's formation to the mature structure. The cloaca is the common chamber into which intestinal, genital and urinary canals open in vertebrates.	tmpzr1t_l9r_go_relaxed.owl	cloacal development							bf	2011-05-06T01:54:35Z					biological_process											owl:Class	
GO:1903464	biolink:NamedThing	negative regulation of mitotic cell cycle DNA replication	Any process that stops, prevents or reduces the frequency, rate or extent of mitotic cell cycle DNA replication.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of DNA replication involved in S phase involved in mitotic cell cycle|downregulation of mitotic nuclear cell cycle DNA replication|downregulation of nuclear cell cycle DNA replication involved in mitotic cell cycle|inhibition of mitotic nuclear cell cycle DNA replication|down regulation of DNA replication during S phase involved in mitotic cell cycle|down regulation of nuclear cell cycle DNA replication involved in mitotic cell cycle|inhibition of DNA replication during S phase involved in mitotic cell cycle|down regulation of mitotic nuclear cell cycle DNA replication|negative regulation of nuclear cell cycle DNA replication involved in mitotic cell cycle|down-regulation of DNA replication involved in S phase involved in mitotic cell cycle|down-regulation of mitotic cell cycle DNA replication|negative regulation of DNA replication involved in S-phase involved in mitotic cell cycle|down regulation of mitotic cell cycle DNA replication|downregulation of DNA replication involved in S phase involved in mitotic cell cycle|downregulation of DNA replication involved in S-phase involved in mitotic cell cycle|negative regulation of mitotic nuclear cell cycle DNA replication|down-regulation of nuclear cell cycle DNA replication involved in mitotic cell cycle|inhibition of mitotic cell cycle DNA replication|down-regulation of mitotic nuclear cell cycle DNA replication|down regulation of DNA replication involved in S-phase involved in mitotic cell cycle|inhibition of DNA replication involved in S phase involved in mitotic cell cycle|down-regulation of DNA replication during S phase involved in mitotic cell cycle|inhibition of DNA replication involved in S-phase involved in mitotic cell cycle|downregulation of mitotic cell cycle DNA replication|downregulation of DNA replication during S phase involved in mitotic cell cycle|negative regulation of DNA replication during S phase involved in mitotic cell cycle|down regulation of DNA replication involved in S phase involved in mitotic cell cycle|down-regulation of DNA replication involved in S-phase involved in mitotic cell cycle|inhibition of nuclear cell cycle DNA replication involved in mitotic cell cycle							vw	2014-09-23T13:38:33Z					biological_process											owl:Class	
GO:1902969	biolink:NamedThing	mitotic DNA replication	Any nuclear DNA replication that is involved in a mitotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl	DNA replication involved in S-phase involved in mitotic cell cycle|mitotic cell cycle DNA replication|nuclear cell cycle DNA replication involved in mitotic cell cycle|mitotic nuclear cell cycle DNA replication|DNA replication during S phase involved in mitotic cell cycle|DNA replication involved in S phase involved in mitotic cell cycle							jl	2014-05-06T15:03:03Z					biological_process											owl:Class	
GO:0007377	biolink:NamedThing	germ-band extension	Elongation of the germ band on the ventral side of the embryo, accompanied by a halving in width. The elongation process pushes the posterior midgut invagination closed and compresses the amnioserosa further.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0010004	biolink:NamedThing	gastrulation involving germ band extension	A complex and coordinated series of cellular movements, including germ band extension, that occurs at the end of cleavage during embryonic development. An example of this process is found in Drosophila melanogaster.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0003899	biolink:NamedThing	DNA-directed 5'-3' RNA polymerase activity	Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template, i.e. the catalysis of DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'.	tmpzr1t_l9r_go_relaxed.owl	DNA-directed RNA polymerase I activity|DNA-dependent RNA polymerase activity|RNA nucleotidyltransferase (DNA-directed) activity|DNA-dependent RNA nucleotidyltransferase activity|DNA-directed RNA polymerase activity|RNA polymerase III activity|deoxyribonucleic acid-dependent ribonucleic acid polymerase activity|transcriptase|DNA-dependent ribonucleate nucleotidyltransferase activity|RNA polymerase II activity|DNA-directed RNA polymerase II activity|C RNA formation factors|RNA polymerase I activity|nucleoside-triphosphate:RNA nucleotidyltransferase (DNA-directed) activity|DNA-directed RNA polymerase III activity|C ribonucleic acid formation factors				Reactome:R-HSA-167115|Reactome:R-HSA-427366|Reactome:R-HSA-6781824|Reactome:R-HSA-75869|Reactome:R-HSA-5601926|Reactome:R-HSA-9697084|Reactome:R-HSA-167121|Reactome:R-HSA-203901|Reactome:R-HSA-75850|Reactome:R-HSA-75873|Reactome:R-HSA-167136|Reactome:R-HSA-111264|Reactome:R-HSA-76576|Reactome:R-HSA-9697085|MetaCyc:DNA-DIRECTED-RNA-POLYMERASE-RXN|EC:2.7.7.6|Reactome:R-HSA-174425|Reactome:R-HSA-68913|Reactome:R-HSA-167117|Reactome:R-HSA-167113|Reactome:R-HSA-9670149|Reactome:R-HSA-74986							GO:0000129		molecular_function											owl:Class	
GO:0014896	biolink:NamedThing	muscle hypertrophy	The muscle system process that results in enlargement or overgrowth of all or part of a muscle organ due to an increase in the size of its muscle cells. Physiological hypertrophy is a normal process during development (it stops in cardiac muscle after adolescence) and can also be brought on in response to demand. In athletes cardiac and skeletal muscles undergo hypertrophy stimulated by increasing muscle activity on exercise. Smooth muscle cells in the uterus undergo hypertrophy during pregnancy.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Muscle_hypertrophy									biological_process											owl:Class	
GO:1901089	biolink:NamedThing	acetate ester metabolic process involved in fermentation	Any acetate ester metabolic process that is involved in fermentation.	tmpzr1t_l9r_go_relaxed.owl	acetate ester metabolic process during fermentation							rb	2012-07-05T11:47:17Z					biological_process											owl:Class	
GO:0006113	biolink:NamedThing	fermentation	The anaerobic enzymatic conversion of organic compounds, especially carbohydrates, coupling the oxidation and reduction of NAD/H and the generation of adenosine triphosphate (ATP).	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:FERMENTATION-PWY|Wikipedia:Fermentation_(biochemistry)									biological_process											owl:Class	
GO:0032712	biolink:NamedThing	negative regulation of interleukin-3 production	Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-3 production.	tmpzr1t_l9r_go_relaxed.owl	down regulation of interleukin-3 production|downregulation of interleukin-3 production|inhibition of interleukin-3 production|negative regulation of interleukin-3 biosynthetic process|negative regulation of IL-3 production|down-regulation of interleukin-3 production											GO:0045400		biological_process											owl:Class	
GO:0032632	biolink:NamedThing	interleukin-3 production	The appearance of interleukin-3 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	tmpzr1t_l9r_go_relaxed.owl	interleukin-3 biosynthetic process|IL-3 production|interleukin-3 secretion											GO:0072601|GO:0042223		biological_process											owl:Class	
GO:0006360	biolink:NamedThing	transcription by RNA polymerase I	The synthesis of RNA from a DNA template by RNA polymerase I (RNAP I), originating at an RNAP I promoter.	tmpzr1t_l9r_go_relaxed.owl	RNA polymerase I transcription factor activity|transcription from RNA polymerase I promoter|transcription from Pol I promoter	https://github.com/geneontology/go-ontology/issues/14854												biological_process											owl:Class	
GO:0090070	biolink:NamedThing	positive regulation of ribosome biogenesis	Any process that increases the rate, frequency or extent of ribosome biogenesis. Ribosome biogenesis is the cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-09-11T10:32:17Z					biological_process											owl:Class	
GO:0042254	biolink:NamedThing	ribosome biogenesis	A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits; includes transport to the sites of protein synthesis.	tmpzr1t_l9r_go_relaxed.owl	ribosome biogenesis and assembly											GO:0007046		biological_process											owl:Class	
GO:0060446	biolink:NamedThing	branching involved in open tracheal system development	The process in which the anatomical structures of branches in the open tracheal system are generated and organized.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0007424	biolink:NamedThing	open tracheal system development	The process whose specific outcome is the progression of an open tracheal system over time, from its formation to the mature structure. An open tracheal system is a respiratory system, a branched network of epithelial tubes that supplies oxygen to target tissues via spiracles. An example of this is found in Drosophila melanogaster.	tmpzr1t_l9r_go_relaxed.owl						See also the fly_anatomy.ontology term 'tracheal system ; FBbt:00005024'.								biological_process											owl:Class	
GO:0033112	biolink:NamedThing	cyanelle envelope	The double lipid bilayer enclosing the cyanelle and separating its contents from the rest of the cytoplasm; includes the intermembrane space.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0009842	biolink:NamedThing	cyanelle	A plastid that contains unstacked, phycobilisome-bearing thylakoid membranes and is surrounded by a double membrane with a peptidoglycan layer in the intermembrane space between the two envelope membranes. Cyanelles are characteristic of algae in the class Glaucophyta, and may represent an ancestral form of plastid.	tmpzr1t_l9r_go_relaxed.owl	cyanoplast|muroplast													cellular_component											owl:Class	
GO:1903045	biolink:NamedThing	neural crest cell migration involved in sympathetic nervous system development	Any neural crest cell migration that is involved in sympathetic nervous system development.	tmpzr1t_l9r_go_relaxed.owl						Sema3a (O08665, mouse) is involved in neural crest cell migration involved in sympathetic nervous system development		rl	2014-05-22T07:06:02Z					biological_process											owl:Class	
GO:0048485	biolink:NamedThing	sympathetic nervous system development	The process whose specific outcome is the progression of the sympathetic nervous system over time, from its formation to the mature structure. The sympathetic nervous system is one of the two divisions of the vertebrate autonomic nervous system (the other being the parasympathetic nervous system). The sympathetic preganglionic neurons have their cell bodies in the thoracic and lumbar regions of the spinal cord and connect to the paravertebral chain of sympathetic ganglia. Innervate heart and blood vessels, sweat glands, viscera and the adrenal medulla. Most sympathetic neurons, but not all, use noradrenaline as a post-ganglionic neurotransmitter.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0045005	biolink:NamedThing	DNA-dependent DNA replication maintenance of fidelity	A DNA metabolic process that prevents or corrects errors to ensure that DNA is replicated accurately. Errors can be corrected either by intrinsic DNA polymerase proofreading activity or via mismatch repair.	tmpzr1t_l9r_go_relaxed.owl	maintenance of fidelity involved in DNA-dependent DNA replication|maintenance of fidelity during DNA-dependent DNA replication													biological_process											owl:Class	
GO:0006261	biolink:NamedThing	DNA-dependent DNA replication	A DNA replication process that uses parental DNA as a template for the DNA-dependent DNA polymerases that synthesize the new strands.	tmpzr1t_l9r_go_relaxed.owl												GO:0006262|GO:0006263		biological_process											owl:Class	
GO:1900077	biolink:NamedThing	negative regulation of cellular response to insulin stimulus	Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to insulin stimulus.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of cellular response to insulin stimulus|downregulation of cellular response to insulin stimulus|down regulation of cellular response to insulin stimulus|inhibition of cellular response to insulin stimulus							yaf	2012-01-31T11:23:15Z					biological_process											owl:Class	
GO:0098896	biolink:NamedThing	postsynaptic early endosome membrane	The lipid bilayer surrounding a postsynaptic early endosome.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0000022	biolink:NamedThing	mitotic spindle elongation	The cell cycle process in which the distance is lengthened between poles of the mitotic spindle. Mitotic spindle elongation begins during mitotic prophase and ends during mitotic anaphase B.	tmpzr1t_l9r_go_relaxed.owl	spindle elongation during mitosis|microtubule sliding involved in mitotic spindle elongation							pr	2016-04-08T15:06:14Z			GO:1905121		biological_process											owl:Class	
GO:0000070	biolink:NamedThing	mitotic sister chromatid segregation	The cell cycle process in which replicated homologous chromosomes are organized and then physically separated and apportioned to two sets during the mitotic cell cycle. Each replicated chromosome, composed of two sister chromatids, aligns at the cell equator, paired with its homologous partner. One homolog of each morphologic type goes into each of the resulting chromosome sets.	tmpzr1t_l9r_go_relaxed.owl	mitotic sister-chromatid adhesion release|mitotic chromosome segregation											GO:0016359		biological_process											owl:Class	
GO:0015085	biolink:NamedThing	calcium ion transmembrane transporter activity	Enables the transfer of calcium (Ca) ions from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-2534359									molecular_function											owl:Class	
GO:0097204	biolink:NamedThing	phagocytic cup base	The older part of the phagocytic cup where the actin cytoskeleton disassembles, allowing early incoming and outgoing vesicular trafficking.	tmpzr1t_l9r_go_relaxed.owl								pr	2011-12-21T10:29:07Z					cellular_component											owl:Class	
GO:0001891	biolink:NamedThing	phagocytic cup	An invagination of the cell membrane formed by an actin dependent process during phagocytosis. Following internalization it is converted into a phagosome.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0033096	biolink:NamedThing	amyloplast envelope	The double lipid bilayer enclosing the amyloplast and separating its contents from the rest of the cytoplasm; includes the intermembrane space.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0009501	biolink:NamedThing	amyloplast	A plastid whose main function is to synthesize and store starch.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Amyloplast									cellular_component											owl:Class	
GO:1900434	biolink:NamedThing	regulation of filamentous growth of a population of unicellular organisms in response to starvation	Any process that modulates the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to starvation.	tmpzr1t_l9r_go_relaxed.owl								di	2012-04-25T05:54:46Z					biological_process											owl:Class	
GO:0036170	biolink:NamedThing	filamentous growth of a population of unicellular organisms in response to starvation	The process in which a group of unicellular organisms grow in a threadlike, filamentous shape in response to deprivation of nourishment.	tmpzr1t_l9r_go_relaxed.owl								bf	2012-03-27T03:53:28Z					biological_process											owl:Class	
GO:0072019	biolink:NamedThing	proximal convoluted tubule development	The process whose specific outcome is the progression of the proximal convoluted tubule over time, from its formation to the mature structure. The proximal convoluted tubule is the most proximal portion of the proximal tubule and extends from the glomerular capsule to the proximal straight tubule.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-01-25T02:35:35Z					biological_process											owl:Class	
GO:0072014	biolink:NamedThing	proximal tubule development	The process whose specific outcome is the progression of the proximal tubule over time, from its formation to the mature structure. In mammals, the proximal tubule is a nephron tubule that connects Bowman's capsule to the descending thin limb of the loop of Henle. It has a brush border epithelial morphology.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-01-25T02:33:46Z					biological_process											owl:Class	
GO:0002842	biolink:NamedThing	positive regulation of T cell mediated immune response to tumor cell	Any process that activates or increases the frequency, rate, or extent of a T cell mediated immune response to tumor cell.	tmpzr1t_l9r_go_relaxed.owl	stimulation of T cell mediated immune response to tumor cell|positive regulation of T lymphocyte mediated immune response to tumor cell|positive regulation of T-lymphocyte mediated immune response to tumor cell|activation of T cell mediated immune response to tumor cell|upregulation of T cell mediated immune response to tumor cell|positive regulation of T-cell mediated immune response to tumor cell|up regulation of T cell mediated immune response to tumor cell|up-regulation of T cell mediated immune response to tumor cell|positive regulation of T cell mediated immune response to tumour cell													biological_process											owl:Class	
GO:0002424	biolink:NamedThing	T cell mediated immune response to tumor cell	An immune response mediated by a T cell triggered in response to the presence of a tumor cell.	tmpzr1t_l9r_go_relaxed.owl						Note that this term includes tolerogenic responses to tumor cells mediated by responding T cells.								biological_process											owl:Class	
GO:0001174	biolink:NamedThing	transcriptional start site selection at RNA polymerase II promoter	Any process involved in the selection of the specific location within the template strand of an RNA polymerase II promoter for hybridization of the cognate ribonucleotides and formation of first phosphodiester bond within the nascent transcript.	tmpzr1t_l9r_go_relaxed.owl								krc	2011-06-20T01:35:28Z					biological_process											owl:Class	
GO:1900313	biolink:NamedThing	negative regulation of maltohexaose transport	Any process that stops, prevents or reduces the frequency, rate or extent of maltohexaose transport.	tmpzr1t_l9r_go_relaxed.owl	down regulation of maltohexaose transport|down-regulation of maltohexaose transport|downregulation of maltohexaose transport|inhibition of maltohexaose transport							tt	2012-04-05T07:59:26Z					biological_process											owl:Class	
GO:2001103	biolink:NamedThing	maltohexaose transport	The directed movement of a maltohexaoseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl								jl	2011-09-21T02:21:40Z					biological_process											owl:Class	
GO:0006931	biolink:NamedThing	substrate-dependent cell migration, cell attachment to substrate	The formation of adhesions that stabilize protrusions at the leading edge of a migrating cell; involves integrin activation, clustering, and the recruitment of structural and signaling components to nascent adhesions.	tmpzr1t_l9r_go_relaxed.owl	substrate-bound cell migration, cell attachment to substrate													biological_process											owl:Class	
GO:0006929	biolink:NamedThing	substrate-dependent cell migration	The orderly movement of a cell from one site to another along a substrate such as the extracellular matrix; the migrating cell forms a protrusion that attaches to the substrate.	tmpzr1t_l9r_go_relaxed.owl	substrate-bound cell migration													biological_process											owl:Class	
GO:1904007	biolink:NamedThing	positive regulation of phospholipase D activity	Any process that activates or increases the frequency, rate or extent of phospholipase D activity.	tmpzr1t_l9r_go_relaxed.owl	up regulation of choline phosphatase activity|up-regulation of phosphatidylcholine phosphatidohydrolase activity|up-regulation of phospholipase D activity|up regulation of phosphatidylcholine phosphatidohydrolase activity|activation of choline phosphatase activity|up-regulation of lecithinase D activity|positive regulation of lipophosphodiesterase II activity|up regulation of lecithinase D activity|upregulation of lecithinase D activity|activation of lecithinase D activity|activation of phospholipase D activity|up regulation of phospholipase D activity|positive regulation of choline phosphatase activity|up regulation of lipophosphodiesterase II activity|activation of phosphatidylcholine phosphatidohydrolase activity|positive regulation of phosphatidylcholine phosphatidohydrolase activity|up-regulation of lipophosphodiesterase II activity|up-regulation of choline phosphatase activity|upregulation of phosphatidylcholine phosphatidohydrolase activity|positive regulation of lecithinase D activity|upregulation of choline phosphatase activity|upregulation of phospholipase D activity|upregulation of lipophosphodiesterase II activity|activation of lipophosphodiesterase II activity							sl	2015-03-06T17:20:17Z					biological_process											owl:Class	
GO:0004630	biolink:NamedThing	phospholipase D activity	Catalysis of the reaction: a phosphatidylcholine + H2O = choline + a phosphatidate.	tmpzr1t_l9r_go_relaxed.owl	lecithinase D activity|choline phosphatase activity|phosphatidylcholine phosphatidohydrolase activity|lipophosphodiesterase II activity				MetaCyc:PHOSCHOL-RXN|RHEA:14445|Reactome:R-HSA-1483142|EC:3.1.4.4|Reactome:R-HSA-1483182|Reactome:R-HSA-2029471									molecular_function											owl:Class	
GO:0071663	biolink:NamedThing	positive regulation of granzyme B production	Any process that activates or increases the frequency, rate, or extent of production of granzyme B.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-02-12T10:41:14Z					biological_process											owl:Class	
GO:0048898	biolink:NamedThing	anterior lateral line system development	The process whose specific outcome is the progression of the anterior lateral line system over time, from its formation to the mature structure. The anterior lateral line system develops from cranial ectodermal placodes, situated between the eye and the ear, that give rise to both the neuromasts and the anterior lateral line sensory nerves that innervate the neuromasts. The anterior lateral line system consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the head of all fishes and most amphibians and are innervated by several lateral line nerves, which project to the hindbrain. The anterior lateral line system is stimulated by local water displacements and vibrations, and detects propulsion of the fish through the water, as well as facilitating shoaling, prey capture, and predator and obstacle avoidance.	tmpzr1t_l9r_go_relaxed.owl	ALL system development													biological_process											owl:Class	
GO:0048881	biolink:NamedThing	mechanosensory lateral line system development	The process whose specific outcome is the progression of the mechanosensory lateral line system over time, from its formation to the mature structure. The mechanosensory lateral line system consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the head and body of all fishes and most amphibians. The neuromasts are innervated by several lateral line nerves, which project primarily to the hindbrain. The mechanosensory lateral line system is stimulated by local water displacements and vibrations, and detects propulsion of the fish through the water, as well as facilitating shoaling, prey capture, and predator and obstacle avoidance.	tmpzr1t_l9r_go_relaxed.owl	LL system development													biological_process											owl:Class	
GO:2000657	biolink:NamedThing	negative regulation of apolipoprotein binding	Any process that stops, prevents or reduces the frequency, rate or extent of apolipoprotein binding.	tmpzr1t_l9r_go_relaxed.owl								vk	2011-05-02T05:33:44Z					biological_process											owl:Class	
GO:0034185	biolink:NamedThing	apolipoprotein binding	Binding to an apolipoprotein, the protein component of a lipoprotein complex.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0000325	biolink:NamedThing	plant-type vacuole	A closed structure that is completely surrounded by a unit membrane, contains liquid, and retains the same shape regardless of cell cycle phase. An example of this structure is found in Arabidopsis thaliana.	tmpzr1t_l9r_go_relaxed.owl	vacuole, cell cycle-independent morphology													cellular_component											owl:Class	
GO:0075713	biolink:NamedThing	establishment of integrated proviral latency	A process by which the virus integrates into the host genome and establishes as a stable provirus or prophage.	tmpzr1t_l9r_go_relaxed.owl	prophage integration|provirus integration				VZ:980			jl	2009-05-07T02:28:41Z			GO:0019047		biological_process											owl:Class	
GO:0044826	biolink:NamedThing	viral genome integration into host DNA	The insertion into a host genome of viral DNA, usually by the action of an integrase enzyme. Once integrated, the provirus persists in the host cell and serves as a template for the transcription of viral genes and replication of the viral genome, leading to the production of new viruses.	tmpzr1t_l9r_go_relaxed.owl	viral genome integration							jl	2014-02-04T16:58:43Z					biological_process											owl:Class	
GO:0099403	biolink:NamedThing	maintenance of mitotic sister chromatid cohesion, telomeric	The process in which the association between sister chromatids of a replicated chromosome along the length of the telomeric region is maintained as chromosomes condense, attach to the spindle in a bipolar orientation, and congress to the metaphase plate during a mitotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl	maintenance of sister chromatin cohesion at telomere at mitosis|maintenance of telomeric mitotic sister chromatin cohesion|maintenance of mitotic sister chromatin cohesion at telomere													biological_process											owl:Class	
GO:0001837	biolink:NamedThing	epithelial to mesenchymal transition	A transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell.	tmpzr1t_l9r_go_relaxed.owl	mesenchymal cell differentiation from epithelial cell|EMT|epithelial-mesenchymal transition													biological_process											owl:Class	
GO:1901901	biolink:NamedThing	regulation of protein localization to cell division site involved in cytokinesis	Any regulation of protein localization to cell division site that is involved in cytokinesis.	tmpzr1t_l9r_go_relaxed.owl	regulation of protein localisation to cell division site involved in cytokinesis							dph	2013-02-12T18:01:34Z					biological_process											owl:Class	
GO:1902388	biolink:NamedThing	ceramide 1-phosphate transfer activity	Removes a ceramide 1-phosphate from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle.	tmpzr1t_l9r_go_relaxed.owl	ceramide 1-phosphate carrier activity|ceramide 1-phosphate transporter activity|intermembrane ceramide 1-phosphate transfer activity				Reactome:R-HSA-5339535			uh	2013-09-05T05:57:55Z					molecular_function											owl:Class	
GO:1902389	biolink:NamedThing	ceramide 1-phosphate transport	The directed movement of a ceramide 1-phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl								uh	2013-09-05T06:02:35Z					biological_process											owl:Class	
GO:0042676	biolink:NamedThing	compound eye cone cell fate commitment	The process in which the cone cells of the compound eye, the lens-secreting cells in the ommatidia, adopt pathways of differentiation that lead to the establishment of their distinct cell type.	tmpzr1t_l9r_go_relaxed.owl												GO:0007466		biological_process											owl:Class	
GO:0075264	biolink:NamedThing	regulation of oogonium development	Any process that modulates the frequency, rate or extent of oogonium development, a process that leads to the formation of a female gametangium of oomycetes, containing one or more gametes.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0075263	biolink:NamedThing	oogonium development	The process that leads to the development of an oogonium, a female gametangium of Oomycetes, containing one or more gametes.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0001839	biolink:NamedThing	neural plate morphogenesis	The process in which the anatomical structures of the neural plate are generated and organized. The neural plate is a specialized region of columnar epithelial cells in the dorsal ectoderm that will give rise to nervous system tissue.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0001840	biolink:NamedThing	neural plate development	The process whose specific outcome is the progression of the neural plate over time, from its formation to the mature structure. The neural plate is a flat, thickened layer of ectodermal cells. The underlying dorsal mesoderm signals the ectodermal cells above it to elongate into columnar neural plate cells. The neural plate subsequently develops into the neural tube, which gives rise to the central nervous system.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1904476	biolink:NamedThing	negative regulation of small GTPase binding	Any process that stops, prevents or reduces the frequency, rate or extent of small GTPase binding.	tmpzr1t_l9r_go_relaxed.owl	downregulation of small GTPase binding|down regulation of small GTPase binding|negative regulation of Ras GTPase binding|down-regulation of Ras GTPase binding|inhibition of small GTPase binding	https://github.com/geneontology/go-ontology/issues/18750						sl	2015-07-10T22:47:38Z					biological_process											owl:Class	
GO:0031267	biolink:NamedThing	small GTPase binding	Binding to a small monomeric GTPase.	tmpzr1t_l9r_go_relaxed.owl	Rho GTPase binding|Rac GTPase binding|Ran protein binding|GTP-Rho binding|Rab GTPase binding|REP|Ran-binding protein|ARF binding|GTP-Ral binding|Ran GTPase binding|Ras GTPase binding|Ras interactor activity|Ral GTPase binding|Rab interactor activity|ADP-ribosylation factor binding|Rab escort protein activity	https://github.com/geneontology/go-ontology/issues/18750										GO:0017048|GO:0017049|GO:0017016|GO:0017137|GO:0048365|GO:0008536|GO:0017160|GO:0034989|GO:0030306|GO:0005084|GO:0017031		molecular_function											owl:Class	
GO:1903654	biolink:NamedThing	phosphorylation of RNA polymerase II C-terminal domain serine 5 residues involved in positive regulation of transcription elongation from RNA polymerase II promoter	Any phosphorylation of RNA polymerase II C-terminal domain serine 5 residues that is involved in positive regulation of transcription elongation from RNA polymerase II promoter.	tmpzr1t_l9r_go_relaxed.owl								vw	2014-11-25T11:00:43Z					biological_process											owl:Class	
GO:0021508	biolink:NamedThing	floor plate formation	The formation of a ventral region of glial cells in the neural tube that provides inductive signals for the specification of neuronal cell types. The floor plate is evident at the ventral midline by the neural fold stage.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0060995	biolink:NamedThing	cell-cell signaling involved in kidney development	Any process that mediates the transfer of information from one cell to another and contributes to the progression of the kidney over time, from its formation to the mature organ.	tmpzr1t_l9r_go_relaxed.owl	cell-cell signalling involved in kidney development							dph	2010-01-19T08:33:40Z					biological_process											owl:Class	
GO:0052799	biolink:NamedThing	coenzyme F420-dependent bicyclic nitroimidazole catabolic process	The breakdown of a bicyclic nitroimidazole into simpler components in a process that requires coenzyme F420 and produces reactive nitrogen species. Hydride, from reduced coenzyme F420, is added to the bicyclic nitroimidazole, resulting in unstable substances that break down to form three stable products. The elimination of nitrous acid produces the corresponding des-nitroimidazole; hydrolysis produces a related compound; and further reduction creates an aromatic hydroxylamine metabolite that degrades further. These reactions release hyponitrous acid and nitrous acid, which is unstable and disproportionates into nitric oxide (NO) and other reactive nitrogen intermediates.	tmpzr1t_l9r_go_relaxed.owl	coenzyme F420-dependent nitroimidazole reduction|coenzyme F420-dependent nitroreductase activity|coenzyme F420-dependent nitroimidazole catabolism|coenzyme F420-dependent nitroimidazole breakdown													biological_process											owl:Class	
GO:0071829	biolink:NamedThing	plasma lipoprotein particle disassembly	The disaggregation of a plasma lipoprotein particle into its constituent components.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-09-08T11:14:21Z					biological_process											owl:Class	
GO:0097006	biolink:NamedThing	regulation of plasma lipoprotein particle levels	Any process involved in the maintenance of internal levels of plasma lipoprotein particles within an organism.	tmpzr1t_l9r_go_relaxed.owl	plasma lipoprotein particle homeostasis							pr	2011-03-15T09:52:53Z					biological_process											owl:Class	
GO:1902234	biolink:NamedThing	positive regulation of positive thymic T cell selection	Any process that activates or increases the frequency, rate or extent of positive thymic T cell selection.	tmpzr1t_l9r_go_relaxed.owl	activation of positive thymic T lymphocyte selection|up-regulation of positive thymic T-lymphocyte selection|upregulation of positive thymic T lymphocyte selection|activation of positive thymic T cell selection|up regulation of positive thymic T-lymphocyte selection|activation of positive thymic T-cell selection|upregulation of positive thymic T cell selection|activation of positive thymic T-lymphocyte selection|up-regulation of positive thymic T cell selection|positive regulation of positive thymic T-lymphocyte selection|up regulation of positive thymic T lymphocyte selection|positive regulation of positive thymic T-cell selection|up-regulation of positive thymic T lymphocyte selection|up regulation of positive thymic T-cell selection|up regulation of positive thymic T cell selection|positive regulation of positive thymic T lymphocyte selection|upregulation of positive thymic T-cell selection|upregulation of positive thymic T-lymphocyte selection|up-regulation of positive thymic T-cell selection							lb	2013-06-14T11:19:20Z					biological_process											owl:Class	
GO:0045059	biolink:NamedThing	positive thymic T cell selection	The process of sparing immature T cells in the thymus which react with self-MHC protein complexes with low affinity levels from apoptotic death.	tmpzr1t_l9r_go_relaxed.owl	positive thymic T lymphocyte selection|positive thymic T-lymphocyte selection|positive thymic T-cell selection													biological_process											owl:Class	
GO:0010103	biolink:NamedThing	stomatal complex morphogenesis	The process in which the anatomical structures of the stomatal complex are generated and organized. The stomatal complex is the stomatal guard cells and their associated epidermal cells.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1905536	biolink:NamedThing	negative regulation of eukaryotic translation initiation factor 4F complex assembly	Any process that stops, prevents or reduces the frequency, rate or extent of eukaryotic translation initiation factor 4F complex assembly.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of eIF-4F assembly|down-regulation of eIF-4F assembly|inhibition of eIF-4F assembly|downregulation of eukaryotic translation initiation factor 4F complex assembly|down regulation of eIF4F assembly|down regulation of eukaryotic translation initiation factor 4F complex assembly|downregulation of eIF4F assembly|downregulation of eIF-4F assembly|down regulation of eIF-4F assembly|inhibition of eIF4F assembly|down-regulation of eIF4F assembly|inhibition of eukaryotic translation initiation factor 4F complex assembly|down-regulation of eukaryotic translation initiation factor 4F complex assembly|negative regulation of eIF4F assembly							bc	2016-10-06T14:05:06Z					biological_process											owl:Class	
GO:0097010	biolink:NamedThing	eukaryotic translation initiation factor 4F complex assembly	The aggregation, arrangement and bonding together of a set of components to form the eukaryotic translation initiation factor 4F complex.	tmpzr1t_l9r_go_relaxed.owl	eIF-4F assembly|eIF4F assembly							pr	2011-03-21T04:19:26Z					biological_process											owl:Class	
GO:0110149	biolink:NamedThing	regulation of biomineralization	Any process that modulates the frequency, rate or extent of biomineralization, the formation and deposition of mineral crystals by living organisms.	tmpzr1t_l9r_go_relaxed.owl	regulation of biomineralisation|regulation of mineralization|regulation of biomineral formation|regulation of mineralisation							kmv	2019-06-10T18:06:59Z					biological_process											owl:Class	
GO:0048356	biolink:NamedThing	root epithelial mucilage biosynthetic process	The chemical reactions and pathways resulting in the formation of mucilage that occur in the root epithelium; mucilage is normally synthesized during root growth.	tmpzr1t_l9r_go_relaxed.owl	root epithelial mucilage anabolism|root epithelial mucilage synthesis|root epithelial mucilage formation|root epithelial mucilage biosynthesis													biological_process											owl:Class	
GO:0048361	biolink:NamedThing	root epithelial mucilage metabolic process	The chemical reactions and pathways involving mucilage that occur in the root epithelium; mucilage is normally synthesized during root growth.	tmpzr1t_l9r_go_relaxed.owl	root epithelial mucilage metabolism													biological_process											owl:Class	
GO:1905885	biolink:NamedThing	positive regulation of triglyceride transport	Any process that activates or increases the frequency, rate or extent of triglyceride transport.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of triacylglycerol transport|activation of triglyceride transport|up-regulation of triglyceride transport|up regulation of triglyceride transport|upregulation of triacylglycerol transport|up regulation of triacylglycerol transport|activation of triacylglycerol transport|upregulation of triglyceride transport|up-regulation of triacylglycerol transport							rz	2017-01-31T11:32:47Z					biological_process											owl:Class	
GO:0034197	biolink:NamedThing	triglyceride transport	The directed movement of triglyceride into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Triglycerides are important components of plant oils, animal fats and animal plasma lipoproteins.	tmpzr1t_l9r_go_relaxed.owl	triacylglycerol transport													biological_process											owl:Class	
GO:0008583	biolink:NamedThing	mystery cell differentiation	The process in which an undifferentiated cell acquires the features of a mystery cell. The mystery cells are a precluster of cells that emerge from the compound eye morphogenetic furrow, normally positioned between R3 and R4. They then disappear into the surrounding pool of undifferentiated cells and have no known fate in the mature ommatidium. An example of this process is found in Drosophila melanogaster.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0001745	biolink:NamedThing	compound eye morphogenesis	The morphogenetic process in which the anatomical structures of the compound eye are generated and organized. The adult compound eye is a precise assembly of 700-800 ommatidia. Each ommatidium is composed of 20 cells, identified by cell type and position. An example of compound eye morphogenesis is found in Drosophila melanogaster.	tmpzr1t_l9r_go_relaxed.owl	insect-type retina morphogenesis													biological_process											owl:Class	
GO:0061452	biolink:NamedThing	retrotrapezoid nucleus neuron differentiation	The process in which a relatively unspecialized cell acquires specialized features of a neuron whose cell body resides in the retrotrapezoid nucleus.	tmpzr1t_l9r_go_relaxed.owl								dph	2012-07-19T12:43:18Z					biological_process											owl:Class	
GO:0072513	biolink:NamedThing	positive regulation of secondary heart field cardioblast proliferation	Any process that activates or increases the frequency, rate or extent of cardioblast proliferation in the second heart field. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating. The secondary heart field is the region of the heart that will form the majority of the mesodermal component of the right ventricle, the arterial pole (outflow tract) and the venous pole (inflow tract).	tmpzr1t_l9r_go_relaxed.owl	negative regulation of second heart field cardioblast proliferation							mah	2010-12-17T10:16:43Z					biological_process											owl:Class	
GO:0021744	biolink:NamedThing	dorsal motor nucleus of vagus nerve development	The process whose specific outcome is the progression of the dorsal motor nucleus of the vagus nerve over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0021550	biolink:NamedThing	medulla oblongata development	The process whose specific outcome is the progression of the medulla oblongata over time, from its formation to the mature structure. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate.	tmpzr1t_l9r_go_relaxed.owl	myelencephalon development|medulla development													biological_process											owl:Class	
GO:0150075	biolink:NamedThing	negative regulation of protein-glutamine gamma-glutamyltransferase activity	Any process that stops, prevents or reduces the frequency, rate or extent of protein-glutamine gamma-glutamyltransferase activity.	tmpzr1t_l9r_go_relaxed.owl								bc	2018-07-25T10:10:24Z					biological_process											owl:Class	
GO:0003810	biolink:NamedThing	protein-glutamine gamma-glutamyltransferase activity	Catalysis of the reaction: protein glutamine + alkylamine = protein N5-alkylglutamine + NH3. This reaction is the formation of the N6-(L-isoglutamyl)-L-lysine isopeptide, resulting in cross-linking polypeptide chains; the gamma-carboxamide groups of peptidyl-glutamine residues act as acyl donors, and the 6-amino-groups of peptidyl-lysine residues act as acceptors, to give intra- and intermolecular N6-(5-glutamyl)lysine cross-links.	tmpzr1t_l9r_go_relaxed.owl	TGase activity|protein-glutamine:amine gamma-glutamyltransferase|polyamine transglutaminase activity|tissue transglutaminase|factor XIIIa|fibrin stabilizing factor|fibrinoligase activity|R-glutaminyl-peptide:amine gamma-glutamyl transferase activity|transglutaminase activity|glutaminylpeptide gamma-glutamyltransferase activity				Reactome:R-HSA-140851|RESID:AA0124|EC:2.3.2.13|MetaCyc:2.3.2.13-RXN|RHEA:54816|Reactome:R-HSA-6810894									molecular_function											owl:Class	
GO:1903596	biolink:NamedThing	regulation of gap junction assembly	Any process that modulates the frequency, rate or extent of gap junction assembly.	tmpzr1t_l9r_go_relaxed.owl								rl	2014-11-07T18:51:36Z					biological_process											owl:Class	
GO:0016264	biolink:NamedThing	gap junction assembly	Assembly of gap junctions, which are found in most animal tissues, and serve as direct connections between the cytoplasms of adjacent cells. They provide open channels through the plasma membrane, allowing ions and small molecules (less than approximately a thousand daltons) to diffuse freely between neighboring cells, but preventing the passage of proteins and nucleic acids.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1901796	biolink:NamedThing	regulation of signal transduction by p53 class mediator	Any process that modulates the frequency, rate or extent of signal transduction by p53 class mediator.	tmpzr1t_l9r_go_relaxed.owl								hjd	2013-01-18T21:51:39Z					biological_process											owl:Class	
GO:0051315	biolink:NamedThing	attachment of mitotic spindle microtubules to kinetochore	The cell cycle process in which spindle microtubules become physically associated with the proteins making up the kinetochore complex as part of mitotic metaphase plate congression.	tmpzr1t_l9r_go_relaxed.owl	attachment of spindle microtubules to mitotic chromosome|mitotic bipolar attachment|attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation|attachment of spindle microtubules to kinetochore during mitosis|attachment of spindle microtubules to kinetochore involved in mitosis					This class covers transient, lateral attachment to microtubules as well as stable, correctly oriented, end-on attachment (biorientation)						GO:0051314		biological_process											owl:Class	
GO:1905538	biolink:NamedThing	polysome binding	Binding to a polysome.	tmpzr1t_l9r_go_relaxed.owl	polyribosome binding							bc	2016-10-07T14:02:53Z					molecular_function											owl:Class	
GO:0110085	biolink:NamedThing	mitotic actomyosin contractile ring	A cytoskeletal structure composed of actin filaments, myosin, and myosin-associated proteins that forms beneath the plasma membrane of many cells, including animal cells and yeast cells, in a plane perpendicular to the axis of the mitotic spindle, i.e. the cell division plane. Ring contraction is associated with centripetal growth of the membrane that divides the cytoplasm of the two future daughter cells. In animal cells, the mitotic contractile ring is located inside the plasma membrane at the location of the cleavage furrow. In budding fungal cells, e.g. mitotic S. cerevisiae cells, the mitotic contractile ring forms beneath the plasma membrane at the mother-bud neck before mitosis.	tmpzr1t_l9r_go_relaxed.owl								kmv	2018-02-12T17:04:02Z					cellular_component											owl:Class	
GO:1902732	biolink:NamedThing	positive regulation of chondrocyte proliferation	Any process that increases the frequency, rate or extent of the multiplication or reproduction of chondrocytes by cell division, resulting in the expansion of their population. A chondrocyte is a polymorphic cell that forms cartilage.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of chondrocyte cell proliferation|up regulation of cartilage cell proliferation|activation of chondrocyte cell proliferation|activation of cartilage cell proliferation|positive regulation of cartilage cell proliferation|upregulation of chondrocyte cell proliferation|up regulation of chondrocyte proliferation|upregulation of chondrocyte proliferation|positive regulation of chondrocyte cell proliferation|upregulation of cartilage cell proliferation|up regulation of chondrocyte cell proliferation|activation of chondrocyte proliferation|up-regulation of cartilage cell proliferation|up-regulation of chondrocyte proliferation							mr	2014-02-24T16:11:18Z					biological_process											owl:Class	
GO:0035988	biolink:NamedThing	chondrocyte proliferation	The multiplication or reproduction of chondrocytes by cell division, resulting in the expansion of their population. A chondrocyte is a polymorphic cell that forms cartilage.	tmpzr1t_l9r_go_relaxed.owl	cartilage cell proliferation|chondrocyte cell proliferation							bf	2011-08-25T04:53:40Z					biological_process											owl:Class	
GO:0099027	biolink:NamedThing	anchored component of presynaptic endocytic zone membrane	The component of the presynaptic endocytic zone membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0098835	biolink:NamedThing	presynaptic endocytic zone membrane	The region of the presynaptic membrane that is part of the presynaptic endocytic zone - where synaptic vesicles are endocytosed and recycled following release.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0016847	biolink:NamedThing	1-aminocyclopropane-1-carboxylate synthase activity	Catalysis of the reaction: S-adenosyl-L-methionine(1+) = 1-aminocyclopropane-1-carboxylate + S-methyl-5'-thioadenosine + H(+).	tmpzr1t_l9r_go_relaxed.owl	aminocyclopropanecarboxylate synthase activity|S-adenosyl-L-methionine methylthioadenosine-lyase activity|1-aminocyclopropane-1-carboxylate synthetase activity|ACC synthase activity|L-VG deaminase activity|1-aminocyclopropanecarboxylate synthase activity|1-aminocyclopropane-1-carboxylic acid synthase activity|L-vinylglycine deaminase activity|aminocyclopropanecarboxylic acid synthase activity|S-adenosyl-L-methionine methylthioadenosine-lyase (1-aminocyclopropane-1-carboxylate-forming)				MetaCyc:4.4.1.14-RXN|KEGG_REACTION:R00179|RHEA:21744|EC:4.4.1.14	Note that this function was formerly EC:4.1.99.4.						GO:0034100		molecular_function											owl:Class	
GO:0042218	biolink:NamedThing	1-aminocyclopropane-1-carboxylate biosynthetic process	The chemical reactions and pathways resulting in the formation of 1-aminocyclopropane-1-carboxylate, a natural product found in plant tissues. It is a key intermediate in the biosynthesis of ethylene (ethene), a fruit-ripening hormone in plants.	tmpzr1t_l9r_go_relaxed.owl	1-aminocyclopropane-1-carboxylate synthesis|1-aminocyclopropane-1-carboxylate formation|1-aminocyclopropane-1-carboxylate biosynthesis|1-aminocyclopropane-1-carboxylate anabolism													biological_process											owl:Class	
GO:0031913	biolink:NamedThing	contractile vacuole pore	Stable structure that regulates the flow of liquid between the contractile vacuole and the surrounding medium.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0031164	biolink:NamedThing	contractile vacuolar membrane	The lipid bilayer surrounding the contractile vacuole.	tmpzr1t_l9r_go_relaxed.owl	contractile vacuole membrane													cellular_component											owl:Class	
GO:0098905	biolink:NamedThing	regulation of bundle of His cell action potential	Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a cardiac muscle cell of the bundle of His. This typically occurs via modulation of the activity or expression of voltage-gated ion channels.	tmpzr1t_l9r_go_relaxed.owl	regulation of bundle of His cardiac muscle cell action potential							dph	2011-11-15T12:01:18Z					biological_process											owl:Class	
GO:0062199	biolink:NamedThing	chromosome, centromeric inner repeat region	The portion of the centromeric region of a chromosome that contains the inner inverted repeat region of a modular centromere and part of the central core surrounding a non-conserved central region. This region is adjacent to the central core, on each chromosome arm.	tmpzr1t_l9r_go_relaxed.owl	chromosome, centric outer repeat region							dph	2019-12-11T20:38:14Z					cellular_component											owl:Class	
GO:0000775	biolink:NamedThing	chromosome, centromeric region	The region of a chromosome that includes the centromeric DNA and associated proteins. In monocentric chromosomes, this region corresponds to a single area of the chromosome, whereas in holocentric chromosomes, it is evenly distributed along the chromosome.	tmpzr1t_l9r_go_relaxed.owl	centromere|chromosome, pericentric region|chromosome, centric region|centromere complex				SO:0000577	Note that this term can be used in place of the obsolete cellular component term 'centromere ; GO:0005698'.						GO:0097521		cellular_component											owl:Class	
GO:1902902	biolink:NamedThing	negative regulation of autophagosome assembly	Any process that stops, prevents or reduces the frequency, rate or extent of autophagosome assembly.	tmpzr1t_l9r_go_relaxed.owl	inhibition of autophagosome biosynthesis|negative regulation of autophagic vacuole formation|inhibition of autophagosome formation|down-regulation of autophagic vacuole assembly|negative regulation of autophagosome formation|down-regulation of autophagosome biosynthesis|down regulation of autophagic vacuole assembly|negative regulation of PAS formation|inhibition of autophagic vacuole formation|downregulation of autophagosome formation|down regulation of autophagic vacuole formation|downregulation of PAS formation|downregulation of autophagic vacuole formation|downregulation of autophagic vacuole assembly|inhibition of autophagic vacuole assembly|negative regulation of autophagosome biosynthesis|down regulation of autophagosome formation|negative regulation of autophagic vacuole assembly|down-regulation of PAS formation|down-regulation of autophagosome formation|down regulation of autophagosome biosynthesis|downregulation of autophagosome biosynthesis|down regulation of PAS formation|down-regulation of autophagic vacuole formation|inhibition of PAS formation							als	2014-04-15T10:37:40Z					biological_process											owl:Class	
GO:0000045	biolink:NamedThing	autophagosome assembly	The formation of a double membrane-bounded structure, the autophagosome, that occurs when a specialized membrane sac, called the isolation membrane, starts to enclose a portion of the cytoplasm.	tmpzr1t_l9r_go_relaxed.owl	autophagic vacuole assembly|autophagic vacuole formation|autophagosome formation|PAS formation|autophagosome biosynthesis													biological_process											owl:Class	
GO:0010915	biolink:NamedThing	regulation of very-low-density lipoprotein particle clearance	Any process that modulates the rate, frequency or extent of very-low-density lipoprotein particle clearance. Very-low-density lipoprotein particle clearance is the process in which a very-low-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.	tmpzr1t_l9r_go_relaxed.owl	regulation of VLDL particle clearance|regulation of VLDL clearance													biological_process											owl:Class	
GO:0034447	biolink:NamedThing	very-low-density lipoprotein particle clearance	The process in which a very-low-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.	tmpzr1t_l9r_go_relaxed.owl	VLDL clearance													biological_process											owl:Class	
GO:0010898	biolink:NamedThing	positive regulation of triglyceride catabolic process	Any process that increases the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of triglyceride.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of triacylglycerol catabolic process													biological_process											owl:Class	
GO:0019433	biolink:NamedThing	triglyceride catabolic process	The chemical reactions and pathways resulting in the breakdown of a triglyceride, any triester of glycerol.	tmpzr1t_l9r_go_relaxed.owl	triacylglycerol catabolism|triglyceride breakdown|triglyceride catabolism|triglyceride degradation|triacylglycerol catabolic process				MetaCyc:LIPAS-PWY									biological_process											owl:Class	
GO:0032114	biolink:NamedThing	regulation of glucose-6-phosphatase activity	Any process that modulates the frequency, rate or extent of glucose-6-phosphatase activity, the catalysis of the reaction: D-glucose 6-phosphate + H2O = D-glucose + phosphate.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0004346	biolink:NamedThing	glucose-6-phosphatase activity	Catalysis of the reaction: D-glucopyranose 6-phosphate + H2O = D-glucose + phosphate. D-glucopyranose is also known as D-glucose 6-phosphate.	tmpzr1t_l9r_go_relaxed.owl	glucose 6-phosphate phosphatase activity|D-glucose-6-phosphate phosphohydrolase activity				Reactome:R-HSA-3262512|KEGG_REACTION:R00303|Reactome:R-HSA-3282876|EC:3.1.3.9|Reactome:R-HSA-71825|Reactome:R-HSA-3274540|MetaCyc:GLUCOSE-6-PHOSPHATASE-RXN|RHEA:16689|Reactome:R-HSA-3266566									molecular_function											owl:Class	
GO:0002847	biolink:NamedThing	negative regulation of T cell tolerance induction to tumor cell	Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell tolerance induction to tumor cell.	tmpzr1t_l9r_go_relaxed.owl	down regulation of T cell tolerance induction to tumor cell|downregulation of T cell tolerance induction to tumor cell|down-regulation of T cell tolerance induction to tumor cell|inhibition of T cell tolerance induction to tumor cell													biological_process											owl:Class	
GO:1903217	biolink:NamedThing	negative regulation of protein processing involved in protein targeting to mitochondrion	Any process that stops, prevents or reduces the frequency, rate or extent of protein processing involved in protein targeting to mitochondrion.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of protein processing involved in protein targeting to mitochondrion|down regulation of mitochondrial protein processing during import|down-regulation of mitochondrial protein processing during import|downregulation of protein processing involved in protein targeting to mitochondrion|downregulation of mitochondrial protein processing during import|inhibition of protein processing involved in protein targeting to mitochondrion|negative regulation of mitochondrial protein processing during import|down regulation of protein processing involved in protein targeting to mitochondrion|inhibition of mitochondrial protein processing during import							bf	2014-07-24T10:21:00Z					biological_process											owl:Class	
GO:0098862	biolink:NamedThing	cluster of actin-based cell projections	A cell part consisting of multiple, closely packed actin-based cell projections.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0098858	biolink:NamedThing	actin-based cell projection	A cell projection supported by an assembly of actin filaments, and which lacks microtubules.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0019835	biolink:NamedThing	cytolysis	The rupture of cell membranes and the loss of cytoplasm.	tmpzr1t_l9r_go_relaxed.owl	necrosis|autolysin activity|lysis|bacteriolytic toxin activity|holin|lysin activity|bacteriocin activity				Wikipedia:Cytolysis									biological_process											owl:Class	
GO:0007304	biolink:NamedThing	chorion-containing eggshell formation	The construction of a chorion-containing eggshell. An example of this is found in Drosophila melanogaster.	tmpzr1t_l9r_go_relaxed.owl	eggshell formation													biological_process											owl:Class	
GO:0002454	biolink:NamedThing	peripheral B cell deletion	The deletion of B cells by apoptotic process occurring as part of peripheral tolerance induction and B cell selection.	tmpzr1t_l9r_go_relaxed.owl	peripheral B-cell deletion|peripheral B-lymphocyte deletion|peripheral B lymphocyte deletion													biological_process											owl:Class	
GO:0048565	biolink:NamedThing	digestive tract development	The process whose specific outcome is the progression of the digestive tract over time, from its formation to the mature structure. The digestive tract is the anatomical structure through which food passes and is processed.	tmpzr1t_l9r_go_relaxed.owl	gut development|intestinal development|intestine development													biological_process											owl:Class	
GO:1990914	biolink:NamedThing	integral component of periplasmic side of plasma membrane	The component of the plasma membrane consisting of the gene products that penetrate only the periplasmic side of the membrane.	tmpzr1t_l9r_go_relaxed.owl						An example of this is hyaA in E. coli (P69739) in PMID:23260654 (inferred from direct assay).		bhm	2015-12-09T14:38:57Z					cellular_component											owl:Class	
GO:0098567	biolink:NamedThing	periplasmic side of plasma membrane	The side (leaflet) of a plasma membrane that faces the periplasm, and all proteins embedded in it or attached to its surface.	tmpzr1t_l9r_go_relaxed.owl								dos	2013-12-19T09:31:30Z					cellular_component											owl:Class	
GO:0004136	biolink:NamedThing	deoxyadenosine kinase activity	Catalysis of the reaction: 2'-deoxyadenosine + ATP = ADP + dAMP + 2 H(+).	tmpzr1t_l9r_go_relaxed.owl	deoxyadenosine kinase (phosphorylating)|ATP:deoxyadenosine 5'-phosphotransferase activity|purine-deoxyribonucleoside kinase activity				KEGG_REACTION:R02089|MetaCyc:DEOXYADENOSINE-KINASE-RXN|EC:2.7.1.76|RHEA:23452									molecular_function											owl:Class	
GO:0006170	biolink:NamedThing	dAMP biosynthetic process	The chemical reactions and pathways resulting in the formation of dAMP, deoxyadenosine monophosphate (2'-deoxyadenosine 5'-phosphate).	tmpzr1t_l9r_go_relaxed.owl	dAMP formation|dAMP synthesis|dAMP anabolism|dAMP biosynthesis													biological_process											owl:Class	
GO:0060551	biolink:NamedThing	regulation of fructose 1,6-bisphosphate metabolic process	Any process that modulates the rate, frequency or extent of fructose 1,6-bisphosphate metabolism. Fructose 1,6-bisphosphate metabolism is the chemical reactions and pathways involving fructose 1,6-bisphosphate, also known as FBP. The D enantiomer is a metabolic intermediate in glycolysis and gluconeogenesis.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-04-13T02:20:04Z					biological_process											owl:Class	
GO:0030388	biolink:NamedThing	fructose 1,6-bisphosphate metabolic process	The chemical reactions and pathways involving fructose 1,6-bisphosphate, also known as FBP. The D enantiomer is a metabolic intermediate in glycolysis and gluconeogenesis.	tmpzr1t_l9r_go_relaxed.owl	fructose 1,6-bisphosphate metabolism													biological_process											owl:Class	
GO:0060970	biolink:NamedThing	embryonic heart tube dorsal/ventral pattern formation	The regionalization process in which the areas along the dorsal/ventral axis of the embryonic heart tube are established. This process will determine the patterns of cell differentiation along the axis.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-10-06T10:14:53Z					biological_process											owl:Class	
GO:0035050	biolink:NamedThing	embryonic heart tube development	The process whose specific outcome is the progression of the embryonic heart tube over time, from its formation to the mature structure. The heart tube forms as the heart rudiment from the heart field.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0110092	biolink:NamedThing	nucleus leading edge	The area of a motile nucleus closest to the direction of movement.	tmpzr1t_l9r_go_relaxed.owl	horsetail nucleus leading edge							kmv	2018-02-14T22:39:58Z					cellular_component											owl:Class	
GO:0060527	biolink:NamedThing	prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis	The branching morphogenesis process in which the prostate epithelial cords branch freely to create the structure of the prostate acini.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0060526	biolink:NamedThing	prostate glandular acinus morphogenesis	The process in which the prostate glandular acini are generated and organized. The glandular acini are the saclike structures of the gland.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0098791	biolink:NamedThing	Golgi apparatus subcompartment	A compartment that consists of a lumen and an enclosing membrane, and is part of the Golgi apparatus.	tmpzr1t_l9r_go_relaxed.owl	Golgi subcompartment													cellular_component											owl:Class	
GO:0090056	biolink:NamedThing	regulation of chlorophyll metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving chlorophyll.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-08-07T11:47:27Z					biological_process											owl:Class	
GO:0034290	biolink:NamedThing	holin activity	A compound function consisting of the regulated formation of a pore via oligomerisation of an existing pool of subunits in the plasma membrane.  The resulting channel activity directly or indirectly allows murein hydrolyases to access their cell wall substrate.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0044660	biolink:NamedThing	viral release by cytolysis via pore formation in host cell membrane	The killing by a virus of a cell in its host organism by cytolysis, caused by the formation by the virus of pores in its host cell membrane.	tmpzr1t_l9r_go_relaxed.owl	cytolysis by virus via pore formation in host cell membrane|viral exit by cytolysis via pore formation in host cell membrane	https://github.com/geneontology/go-ontology/issues/18852						jl	2012-08-01T13:23:41Z					biological_process											owl:Class	
GO:0072174	biolink:NamedThing	metanephric tubule formation	The developmental process pertaining to the initial formation of a metanephric tubule.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-02-26T02:07:41Z					biological_process											owl:Class	
GO:0061054	biolink:NamedThing	dermatome development	The progression of the dermatome over time, from its initial formation to the mature structure. The dermatome is the portion of a somite that will form skin.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-03-02T12:07:37Z					biological_process											owl:Class	
GO:1902436	biolink:NamedThing	negative regulation of male mating behavior	Any process that stops, prevents or reduces the frequency, rate or extent of male mating behavior.	tmpzr1t_l9r_go_relaxed.owl	down regulation of male mating behavior|down-regulation of male mating behavior|inhibition of male mating behavior|downregulation of male mating behavior							mm2	2013-10-09T15:50:05Z					biological_process											owl:Class	
GO:0033248	biolink:NamedThing	negative regulation of penicillin catabolic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of any antibiotic that contains the condensed beta-lactamthiazolidine ring system.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of penicillin degradation|negative regulation of penicillin catabolism|negative regulation of penicillin breakdown													biological_process											owl:Class	
GO:0043407	biolink:NamedThing	negative regulation of MAP kinase activity	Any process that stops, prevents, or reduces the frequency, rate or extent of MAP kinase activity.	tmpzr1t_l9r_go_relaxed.owl	downregulation of MAPK activity|negative regulation of mitogen activated protein kinase activity|negative regulation of mitogen-activated protein kinase activity|inhibition of MAPK activity|down-regulation of MAPK activity|down regulation of MAPK activity													biological_process											owl:Class	
GO:0070359	biolink:NamedThing	actin polymerization-dependent cell motility involved in migration of symbiont in host	A process involved in the controlled movement of a bacterial cell within a host cell, powered by the continuous polymerization of host actin at one pole of the cell.	tmpzr1t_l9r_go_relaxed.owl	actin polymerization-dependent cell motility involved in migration of symbiont within host													biological_process											owl:Class	
GO:0070360	biolink:NamedThing	migration of symbiont within host by polymerization of host actin	The directional movement of an organism, usually a bacterial cell, from one place to another within its host organism, by a process involving continuous polymerization of host actin at one pole of the symbiont cell. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0002036	biolink:NamedThing	regulation of L-glutamate import across plasma membrane	Any process that modulates the frequency, rate or extent of L-glutamate import into a cell.	tmpzr1t_l9r_go_relaxed.owl	regulation of L-glutamate uptake|regulation of L-glutamate import|regulation of L-glutamate transport							al	2012-06-13T07:34:08Z			GO:1900920		biological_process											owl:Class	
GO:0098712	biolink:NamedThing	L-glutamate import across plasma membrane	The directed movement of L-glutamate from outside of a cell, across the plasma membrane and into the cytosol.	tmpzr1t_l9r_go_relaxed.owl	L-glutamate(1-) import into cell|L-glutamate(1-) import across plasma membrane|L-glutamate import into cell							mah	2013-06-12T12:32:47Z			GO:1990123|GO:1903802		biological_process											owl:Class	
GO:0110083	biolink:NamedThing	positive regulation of protein localization to cell division site involved in mitotic actomyosin contractile ring assembly	Any process that activates or increases the frequency, rate or extent of protein localization to cell division site involved in mitotic actomyosin contractile ring assembly.	tmpzr1t_l9r_go_relaxed.owl								kmv	2018-02-01T19:30:03Z					biological_process											owl:Class	
GO:1903476	biolink:NamedThing	protein localization to cell division site involved in mitotic actomyosin contractile ring assembly	Any protein localization to cell division site that is involved in mitotic actomyosin contractile ring assembly.	tmpzr1t_l9r_go_relaxed.owl	protein localization to cell division site involved in actomyosin contractile ring assembly involved in cytokinesis after mitosis|protein localization to cell division site involved in contractile ring assembly involved in mitotic cytokinesis|protein localisation to cell division site involved in mitotic actomyosin contractile ring assembly							vw	2014-09-23T14:52:37Z					biological_process											owl:Class	
GO:0098895	biolink:NamedThing	postsynaptic endosome membrane	The lipid bilayer surrounding a postsynaptic endosome.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0090186	biolink:NamedThing	regulation of pancreatic juice secretion	Any process that modulates the rate, frequency or extent of pancreatic juice secretion, the regulated release of pancreatic juice by the exocrine pancreas into the upper part of the intestine.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-12-18T11:03:24Z					biological_process											owl:Class	
GO:0030867	biolink:NamedThing	rough endoplasmic reticulum membrane	The lipid bilayer surrounding the rough endoplasmic reticulum.	tmpzr1t_l9r_go_relaxed.owl	rough ER membrane|RER membrane				NIF_Subcellular:sao3089754107									cellular_component											owl:Class	
GO:0014036	biolink:NamedThing	neural crest cell fate specification	The process in which a cell becomes capable of differentiating autonomously into a neural crest cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0060380	biolink:NamedThing	regulation of single-stranded telomeric DNA binding	Any process that modulates the frequency, rate or extent of binding to single-stranded telomeric DNA.	tmpzr1t_l9r_go_relaxed.owl	regulation of telomeric ssDNA binding													biological_process											owl:Class	
GO:0043047	biolink:NamedThing	single-stranded telomeric DNA binding	Binding to single-stranded telomere-associated DNA.	tmpzr1t_l9r_go_relaxed.owl	telomeric ssDNA binding													molecular_function											owl:Class	
GO:0036306	biolink:NamedThing	embryonic heart tube elongation	The developmental growth that results in the increase in length of the embryonic heart tube. The embryonic heart tube is an epithelial tube that will give rise to the mature heart.	tmpzr1t_l9r_go_relaxed.owl								bf	2012-08-08T13:54:37Z					biological_process											owl:Class	
GO:0030988	biolink:NamedThing	high molecular weight kininogen receptor complex	A protein complex that acts as a receptor for high molecular weight kininogens. In humans, this receptor includes the CK1 and uPAR proteins.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0007049	biolink:NamedThing	cell cycle	The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division.	tmpzr1t_l9r_go_relaxed.owl	cell-division cycle				Wikipedia:Cell_cycle									biological_process											owl:Class	
GO:0071026	biolink:NamedThing	cytoplasmic RNA surveillance	The set of processes involved in identifying and degrading defective or aberrant RNAs within the cytoplasm.	tmpzr1t_l9r_go_relaxed.owl	cytoplasmic RNA quality control|cytoplasmic aberrant RNA catabolic process							krc	2009-07-28T03:14:03Z					biological_process											owl:Class	
GO:1903441	biolink:NamedThing	protein localization to ciliary membrane	A process in which a protein is transported to, or maintained in, a location within a ciliary membrane.	tmpzr1t_l9r_go_relaxed.owl	protein localization in ciliary membrane|protein localisation to ciliary membrane|protein localisation in ciliary membrane							pr	2014-09-16T15:15:39Z					biological_process											owl:Class	
GO:0060442	biolink:NamedThing	branching involved in prostate gland morphogenesis	The process in which the branching structure of the prostate gland is generated and organized. A branch is a division or offshoot from a main stem.	tmpzr1t_l9r_go_relaxed.owl	prostate gland branching morphogenesis|prostate branching													biological_process											owl:Class	
GO:0061317	biolink:NamedThing	canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment	The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin and contributing to cardiac muscle cell fate commitment. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes.	tmpzr1t_l9r_go_relaxed.owl	canonical Wnt receptor signaling pathway involved in cardiac muscle cell fate commitment|canonical Wnt-activated signaling pathway involved in cardiac muscle cell fate commitment|canonical Wnt receptor signalling pathway involved in cardiac muscle cell fate commitment							dph	2010-09-24T09:29:21Z					biological_process											owl:Class	
GO:0060923	biolink:NamedThing	cardiac muscle cell fate commitment	The commitment of cells to specific cardiac muscle cell fates and their capacity to differentiate into cardiac muscle cells. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction.	tmpzr1t_l9r_go_relaxed.owl	cardiomyocyte cell fate commitment|heart muscle cell fate commitment							dph	2009-09-29T11:13:32Z					biological_process											owl:Class	
GO:0090152	biolink:NamedThing	establishment of protein localization to mitochondrial membrane involved in mitochondrial fission	The directed movement of a protein to a specific location in the mitochondrial membrane that contributes to mitochondrial fission.	tmpzr1t_l9r_go_relaxed.owl	establishment of protein localisation in mitochondrial membrane involved in mitochondrial fission|establishment of protein localization in mitochondrial membrane involved in mitochondrial fission							tb	2009-12-08T03:18:51Z					biological_process											owl:Class	
GO:0000266	biolink:NamedThing	mitochondrial fission	The division of a mitochondrion within a cell to form two or more separate mitochondrial compartments.	tmpzr1t_l9r_go_relaxed.owl	mitochondrial division|mitochondrial proliferation													biological_process											owl:Class	
GO:0010808	biolink:NamedThing	positive regulation of synaptic vesicle priming	Any process that increases the frequency, rate or extent of synaptic vesicle priming. Synaptic vesicle priming is the formation of SNARE-containing complexes, bringing synaptic vesicle membrane and plasma membranes into close proximity and thereby facilitating membrane fusion.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0046797	biolink:NamedThing	viral procapsid maturation	The refolding and structural rearrangements of individual capsid subunits to transition from the intermediate procapsid, to the more stable capsid structure.	tmpzr1t_l9r_go_relaxed.owl	viral capsid maturation|virion maturation|capsid maturation				UniProtKB-KW:KW-1273									biological_process											owl:Class	
GO:0019075	biolink:NamedThing	virus maturation	The refolding and structural rearrangements of virion parts to transition from the intermediate virion to the more mature virion. Maturation usually involves proteolysis events and changes in the folding of the virion proteins. Can occur inside the host cell or after release.	tmpzr1t_l9r_go_relaxed.owl	bacteriophage maturation|viral maturation													biological_process											owl:Class	
GO:1903272	biolink:NamedThing	positive regulation of cytoplasmic translational elongation through polyproline stretches	Any process that activates or increases the frequency, rate or extent of cytoplasmic translational elongation through polyproline stretches.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of cytoplasmic translational elongation through polyproline stretches|up regulation of cytoplasmic translational elongation through polyproline stretches|activation of cytoplasmic translational elongation through polyproline stretches|upregulation of cytoplasmic translational elongation through polyproline stretches							mcc	2014-08-08T14:54:16Z					biological_process											owl:Class	
GO:0097622	biolink:NamedThing	cytoplasmic translational elongation through polyproline stretches	The successive addition of amino acid residues to a nascent polypeptide chain, proceeding through regions of multiple repeated proline codons, during protein biosynthesis in the cytoplasm.	tmpzr1t_l9r_go_relaxed.owl								pr	2014-08-06T16:29:10Z					biological_process											owl:Class	
GO:0002465	biolink:NamedThing	peripheral tolerance induction	Tolerance induction in the peripheral lymphoid tissues: blood, lymph nodes, spleen, and mucosal-associated lymphoid tissues.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0009862	biolink:NamedThing	systemic acquired resistance, salicylic acid mediated signaling pathway	The series of molecular signals mediated by salicylic acid involved in systemic acquired resistance.	tmpzr1t_l9r_go_relaxed.owl	salicylic acid mediated signaling pathway (systemic acquired resistance)|systemic acquired resistance, salicylic acid mediated signalling pathway													biological_process											owl:Class	
GO:0009627	biolink:NamedThing	systemic acquired resistance	The salicylic acid mediated response to a pathogen which confers broad spectrum resistance.	tmpzr1t_l9r_go_relaxed.owl	salicylic acid-dependent systemic resistance				Wikipedia:Systemic_acquired_resistance									biological_process											owl:Class	
GO:0010863	biolink:NamedThing	positive regulation of phospholipase C activity	Any process that increases the rate of phospholipase C activity.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1900227	biolink:NamedThing	positive regulation of NLRP3 inflammasome complex assembly	Any process that activates or increases the frequency, rate or extent of NLRP3 inflammasome complex assembly.	tmpzr1t_l9r_go_relaxed.owl	up regulation of NLRP3 inflammasome activation|up regulation of NLRP3 inflammasome complex assembly|upregulation of NLRP3 inflammasome activation|activation of NLRP3 inflammasome complex assembly|up-regulation of NLRP3 inflammasome activation|up-regulation of NALP3 inflammasome complex assembly|up-regulation of NLRP3 inflammasome complex assembly|upregulation of NALP3 inflammasome complex assembly|activation of NLRP3 inflammasome activation|up regulation of NALP3 inflammasome complex assembly|upregulation of NLRP3 inflammasome complex assembly|activation of NALP3 inflammasome complex assembly|positive regulation of NALP3 inflammasome complex assembly|positive regulation of NLRP3 inflammasome activation							jl	2012-03-22T04:18:32Z					biological_process											owl:Class	
GO:0044546	biolink:NamedThing	NLRP3 inflammasome complex assembly	The aggregation, arrangement and bonding together of a set of components to form the NLRP3 inflammasome complex, occurring at the level of an individual cell.	tmpzr1t_l9r_go_relaxed.owl	NLRP3 inflammasome activation|NALP3 inflammasome complex assembly	https://github.com/geneontology/go-ontology/issues/21092						jl	2012-03-22T01:27:21Z					biological_process											owl:Class	
GO:0150021	biolink:NamedThing	apical dendrite morphogenesis	The process in which the anatomical structures of an apical dendrite are generated and organized.	tmpzr1t_l9r_go_relaxed.owl								bc	2017-12-22T11:50:00Z					biological_process											owl:Class	
GO:0150022	biolink:NamedThing	apical dendrite development	The process whose specific outcome is the progression of an apical dendrite over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl								bc	2017-12-22T11:52:40Z					biological_process											owl:Class	
GO:0046847	biolink:NamedThing	filopodium assembly	The assembly of a filopodium, a thin, stiff protrusion extended by the leading edge of a motile cell such as a crawling fibroblast or amoeba, or an axonal growth cone.	tmpzr1t_l9r_go_relaxed.owl	filopodia formation|filopodium formation|filopodia biosynthesis													biological_process											owl:Class	
GO:0043629	biolink:NamedThing	ncRNA polyadenylation	The enzymatic addition of a sequence of adenylyl residues at the 3' end of a non-coding RNA (ncRNA) molecule. In eukaryotes, substrates include nuclear non-coding RNAs such as precursors and a variety of incorrectly processed forms of snRNAs, snoRNAs, rRNAs, and tRNAs, as well as discarded RNA fragments which have been removed from ncRNA primary transcripts. Polyadenylation of precursors is often linked to termination of transcription, but polyadenylation of RNAs targeted for degradation may also occur post-transcriptionally. This polyadenylation is important both for 3'-end processing to produce mature ncRNA species and also for targeting incorrectly processed or discarded RNA molecules for degradation.	tmpzr1t_l9r_go_relaxed.owl	non-coding RNA polyadenylation													biological_process											owl:Class	
GO:0070245	biolink:NamedThing	positive regulation of thymocyte apoptotic process	Any process that activates or increases the frequency, rate or extent of thymocyte death by apoptotic process.	tmpzr1t_l9r_go_relaxed.owl	upregulation of thymocyte apoptosis|activation of thymocyte apoptosis|up-regulation of thymocyte apoptosis|stimulation of thymocyte apoptosis|positive regulation of immature T cell apoptosis|up regulation of thymocyte apoptosis|positive regulation of thymocyte apoptosis					Note that a thymocyte is an immature T cell located in the thymus (CL:0000893).								biological_process											owl:Class	
GO:2001028	biolink:NamedThing	positive regulation of endothelial cell chemotaxis	Any process that activates or increases the frequency, rate or extent of endothelial cell chemotaxis.	tmpzr1t_l9r_go_relaxed.owl								rl	2011-08-22T01:07:34Z					biological_process											owl:Class	
GO:0035767	biolink:NamedThing	endothelial cell chemotaxis	The directed movement of an endothelial cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).	tmpzr1t_l9r_go_relaxed.owl								bf	2011-03-31T04:31:37Z					biological_process											owl:Class	
GO:0008545	biolink:NamedThing	JUN kinase kinase activity	Catalysis of the phosphorylation of tyrosine and threonine residues in a c-Jun NH2-terminal kinase (JNK), a member of a subgroup of mitogen-activated protein kinases (MAPKs), which signal in response to cytokines and exposure to environmental stress. JUN kinase kinase (JNKK) is a dual-specificity protein kinase kinase and requires activation by a serine/threonine kinase JUN kinase kinase kinase.	tmpzr1t_l9r_go_relaxed.owl	JNKK				Reactome:R-HSA-168162									molecular_function											owl:Class	
GO:0007254	biolink:NamedThing	JNK cascade	An intracellular protein kinase cascade containing at least a JNK (a MAPK), a JNKK (a MAPKK) and a JUN3K (a MAP3K). The cascade can also contain an additional tier: the upstream MAP4K. The kinases in each tier phosphorylate and activate the kinases in the downstream tier to transmit a signal within a cell.	tmpzr1t_l9r_go_relaxed.owl	JNK2 cascade|MAPK8 cascade|JNK3 cascade|MAPK10 cascade|MAPK9 cascade|SAPK cascade|stress-activated protein kinase cascade|c-Jun N-terminal kinase cascade|JNK1 cascade													biological_process											owl:Class	
GO:0097537	biolink:NamedThing	Y-shaped link	A Y-shaped protein complex in the ciliary transition zone that connects the cilium axoneme to the ciliary necklace. Both protein sorting and protein gating occur at this point in the cilium allowing some, but not all proteins to enter the cilium.	tmpzr1t_l9r_go_relaxed.owl	membrane-microtubule complex|Y-link structure|Y-shaped assemblage|Y-shaped fibre|Y-link|Y-shaped linker|Y-shaped fiber							pr	2013-12-03T16:34:34Z					cellular_component											owl:Class	
GO:0035869	biolink:NamedThing	ciliary transition zone	A region of the cilium between the basal body and proximal segment that is characterized by Y-shaped assemblages that connect axonemal microtubules to the ciliary membrane. The ciliary transition zone appears to function as a gate that controls ciliary membrane composition and separates the cytosol from the ciliary plasm.	tmpzr1t_l9r_go_relaxed.owl	cilium transition zone|connecting cilium|cilial transition zone					Depending on the species, this region may have a distinct geometrically shaped electron-dense structure within the axonemal lumen visible in electron microscopy images; most animals don't display this inner structure. The axoneme extends through the ciliary transition zone, but only consists of the outer doublets. The central pair, axonemal spokes, and dynein complexes are not found in this part of the ciliary shaft. Note that the connecting cilium of the photoreceptor cells is thought to be equivalent to the transition zone.		bf	2011-05-25T03:09:58Z					cellular_component											owl:Class	
GO:0048514	biolink:NamedThing	blood vessel morphogenesis	The process in which the anatomical structures of blood vessels are generated and organized. The blood vessel is the vasculature carrying blood.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0001568	biolink:NamedThing	blood vessel development	The process whose specific outcome is the progression of a blood vessel over time, from its formation to the mature structure. The blood vessel is the vasculature carrying blood.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0045107	biolink:NamedThing	intermediate filament polymerization	Assembly of intermediate filaments by the addition of component monomers to a filament. Polymerization of intermediate filament proteins results from interactions among several distinct binding sites on the constituent proteins. Nuclear lamin head-to-tail polymers arise from one such interaction. Deletion analysis localized the binding sites to the ends of the rod domain that are highly conserved among all intermediate filament proteins. Data indicate that one type of interaction in intermediate filament protein polymerization is the longitudinal binding of dimers via the conserved end segments of the coiled-coil rod domain.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0035847	biolink:NamedThing	uterine epithelium development	The progression of an epithelium of the uterus over time from its initial formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure.	tmpzr1t_l9r_go_relaxed.owl	uterus epithelial development							bf	2011-05-10T10:57:45Z					biological_process											owl:Class	
GO:0060065	biolink:NamedThing	uterus development	The reproductive developmental process whose specific outcome is the progression of the uterus over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl	Mullerian tract development													biological_process											owl:Class	
GO:1901258	biolink:NamedThing	positive regulation of macrophage colony-stimulating factor production	Any process that activates or increases the frequency, rate or extent of macrophage colony-stimulating factor production.	tmpzr1t_l9r_go_relaxed.owl	activation of M-CSF production|positive regulation of M-CSF production|upregulation of M-CSF production|up regulation of M-CSF production|upregulation of macrophage colony-stimulating factor production|up-regulation of macrophage colony-stimulating factor production|up-regulation of M-CSF production|activation of macrophage colony-stimulating factor production|up regulation of macrophage colony-stimulating factor production							vk	2012-08-10T08:28:36Z					biological_process											owl:Class	
GO:0036301	biolink:NamedThing	macrophage colony-stimulating factor production	The appearance of macrophage colony-stimulating factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	tmpzr1t_l9r_go_relaxed.owl	M-CSF production							bf	2012-08-07T14:07:13Z					biological_process											owl:Class	
GO:0070787	biolink:NamedThing	conidiophore development	The process whose specific outcome is the progression of the conidiophore over time, from its formation to the mature structure. The conidiophore is a specialized hypha that extends aerially from the growth substrate and bears conidia, or asexual spores.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-07-08T01:30:36Z					biological_process											owl:Class	
GO:0008347	biolink:NamedThing	glial cell migration	The orderly movement of a glial cell, non-neuronal cells that provide support and nutrition, maintain homeostasis, form myelin, and participate in signal transmission in the nervous system.	tmpzr1t_l9r_go_relaxed.owl	glia cell migration											GO:0043359		biological_process											owl:Class	
GO:0042063	biolink:NamedThing	gliogenesis	The process that results in the generation of glial cells. This includes the production of glial progenitors and their differentiation into mature glia.	tmpzr1t_l9r_go_relaxed.owl	glial cell generation													biological_process											owl:Class	
GO:0098749	biolink:NamedThing	cerebellar neuron development	The process whose specific outcome is the progression of a cerebellar neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0045455	biolink:NamedThing	ecdysteroid metabolic process	The chemical reactions and pathways involving ecdysteroids, a group of polyhydroxylated ketosteroids ubiquitous in insects and other arthropods, in which they initiate post-embryonic development, including the metamorphosis of immature forms and the development of the reproductive system and the maturation of oocytes in adult females.	tmpzr1t_l9r_go_relaxed.owl	ecdysteroid metabolism													biological_process											owl:Class	
GO:0014736	biolink:NamedThing	negative regulation of muscle atrophy	Any process that stops, prevents, or reduces the frequency, rate, or extent of muscle atrophy.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0098912	biolink:NamedThing	membrane depolarization during atrial cardiac muscle cell action potential	The process in which atrial cardiac muscle cell membrane potential changes in the depolarizing direction from the negative resting potential towards the positive membrane potential that will be the peak of the action potential.	tmpzr1t_l9r_go_relaxed.owl	atrial cardiac muscle cell depolarization|electrocardiogram PR interval|atrial depolarization													biological_process											owl:Class	
GO:0086014	biolink:NamedThing	atrial cardiac muscle cell action potential	An action potential that occurs in an atrial cardiac muscle cell.	tmpzr1t_l9r_go_relaxed.owl								tb	2011-11-10T08:49:13Z					biological_process											owl:Class	
GO:2001215	biolink:NamedThing	regulation of hydroxymethylglutaryl-CoA reductase (NADPH) activity	Any process that modulates the frequency, rate or extent of hydroxymethylglutaryl-CoA reductase (NADPH) activity.	tmpzr1t_l9r_go_relaxed.owl	regulation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase activity|regulation of HMG-CoA reductase activity							bf	2011-11-16T11:34:11Z					biological_process											owl:Class	
GO:0004420	biolink:NamedThing	hydroxymethylglutaryl-CoA reductase (NADPH) activity	Catalysis of the reaction: (R)-mevalonate + CoA + 2 NADP(+) = (S)-3-hydroxy-3-methylglutaryl-CoA + 2 H(+) + 2 NADPH.	tmpzr1t_l9r_go_relaxed.owl	hydroxymethylglutaryl-CoA reductase activity|3-hydroxy-3-methylglutaryl-coenzyme A reductase activity|HMG-CoA reductase activity	https://github.com/geneontology/go-ontology/issues/21411			RHEA:15989|MetaCyc:1.1.1.34-RXN|KEGG_REACTION:R02082|EC:1.1.1.34|Reactome:R-HSA-191352							GO:0042282		molecular_function											owl:Class	
GO:0031362	biolink:NamedThing	anchored component of external side of plasma membrane	The component of the plasma membrane consisting of the gene products that are tethered to the external side of the membrane only by a covalently attached anchor, such as a lipid group embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping.	tmpzr1t_l9r_go_relaxed.owl	anchored to external side of plasma membrane|anchored to external leaflet of plasma membrane													cellular_component											owl:Class	
GO:0009897	biolink:NamedThing	external side of plasma membrane	The leaflet of the plasma membrane that faces away from the cytoplasm and any proteins embedded or anchored in it or attached to its surface.	tmpzr1t_l9r_go_relaxed.owl	outer surface of cytoplasmic membrane|external leaflet of plasma membrane|juxtamembrane													cellular_component											owl:Class	
GO:1904738	biolink:NamedThing	vascular associated smooth muscle cell migration	The orderly movement of a vascular associated smooth muscle cell from one site to another.	tmpzr1t_l9r_go_relaxed.owl	vascular smooth muscle cell migration							rph	2015-10-15T09:56:00Z					biological_process											owl:Class	
GO:1905822	biolink:NamedThing	regulation of mitotic sister chromatid arm separation	Any process that modulates the frequency, rate or extent of mitotic sister chromatid arm separation.	tmpzr1t_l9r_go_relaxed.owl								als	2017-01-16T13:36:29Z					biological_process											owl:Class	
GO:1990891	biolink:NamedThing	mitotic sister chromatid arm separation	The cell cycle process in which sister chromatid arms are physically detached from each other during mitosis.	tmpzr1t_l9r_go_relaxed.owl								mah	2015-11-03T14:01:16Z					biological_process											owl:Class	
GO:0097729	biolink:NamedThing	9+2 motile cilium	A motile cilium where the axoneme has a ring of nine outer microtubule doublets plus two central microtubules (and is therefore called a 9+2 axoneme).	tmpzr1t_l9r_go_relaxed.owl	motile 9+2 cilium|conventional motile cilium|sperm flagellum					This type of cilia may be present in solitary (so-called flagella, e.g. in sperm) or in multiple copies (so-called conventional motile cilia, e.g. in tracheal epithelium, ependyma or oviduct epithelium).		pr	2016-09-27T15:26:34Z					cellular_component											owl:Class	
GO:2000006	biolink:NamedThing	regulation of metanephric comma-shaped body morphogenesis	Any process that modulates the frequency, rate or extent of metanephric comma-shaped body morphogenesis.	tmpzr1t_l9r_go_relaxed.owl								jl	2010-07-30T02:17:12Z					biological_process											owl:Class	
GO:0072278	biolink:NamedThing	metanephric comma-shaped body morphogenesis	The process in which the metanephric comma-shaped body is generated and organized. The metanephric comma-shaped body is the precursor structure to the metanephric S-shaped body that contributes to the morphogenesis of a nephron in the metanephros.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-04-01T03:14:42Z					biological_process											owl:Class	
GO:1902276	biolink:NamedThing	regulation of pancreatic amylase secretion	Any process that modulates the frequency, rate or extent of pancreatic amylase secretion.	tmpzr1t_l9r_go_relaxed.owl								bf	2013-07-03T12:15:20Z					biological_process											owl:Class	
GO:0006508	biolink:NamedThing	proteolysis	The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds.	tmpzr1t_l9r_go_relaxed.owl	ATP-dependent proteolysis|peptidolysis				Wikipedia:Proteolysis	This term was intentionally placed under 'protein metabolic process ; GO:0019538' rather than 'protein catabolic process ; GO:0030163' to cover all processes centered on breaking peptide bonds, including those involved in protein processing.								biological_process											owl:Class	
GO:0003407	biolink:NamedThing	neural retina development	The progression of the neural retina over time from its initial formation to the mature structure. The neural retina is the part of the retina that contains neurons and photoreceptor cells.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-12-21T02:15:14Z					biological_process											owl:Class	
GO:0030708	biolink:NamedThing	germarium-derived female germ-line cyst encapsulation	Formation of a single follicular epithelium around the germ-line derived cells of a cyst formed in the germarium. An example of this process is found in Drosophila melanogaster.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0007293	biolink:NamedThing	germarium-derived egg chamber formation	Construction of a stage-1 egg chamber in the anterior part of the germarium, from the progeny of germ-line and somatic stem cells. An example of this is found in Drosophila melanogaster.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0110040	biolink:NamedThing	pharynx morphogenesis	The process in which the anatomical structures of the pharynx are generated and organized.	tmpzr1t_l9r_go_relaxed.owl								kmv	2017-07-24T20:51:28Z					biological_process											owl:Class	
GO:0099501	biolink:NamedThing	exocytic vesicle membrane	The lipid bilayer surrounding an exocytic vesicle.	tmpzr1t_l9r_go_relaxed.owl	secretory vesicle membrane													cellular_component											owl:Class	
GO:0010529	biolink:NamedThing	negative regulation of transposition	Any process that decreases the frequency, rate or extent of transposition. Transposition results in the movement of discrete segments of DNA between nonhomologous sites.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0021797	biolink:NamedThing	forebrain anterior/posterior pattern specification	The creation of specific areas of progenitor domains along the anterior-posterior axis of the developing forebrain.	tmpzr1t_l9r_go_relaxed.owl	forebrain anterior-posterior pattern specification													biological_process											owl:Class	
GO:0021871	biolink:NamedThing	forebrain regionalization	The regionalization process resulting in the creation of areas within the forebrain that will direct the behavior of cell migration in differentiation as the forebrain develops.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1902082	biolink:NamedThing	positive regulation of calcium ion import into sarcoplasmic reticulum	Any process that activates or increases the frequency, rate or extent of calcium ion import into sarcoplasmic reticulum.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of calcium ion import into sarcoplasmic reticulum|activation of calcium ion import into sarcoplasmic reticulum|upregulation of calcium ion import into sarcoplasmic reticulum|up regulation of calcium ion import into sarcoplasmic reticulum							rl	2013-04-24T16:08:03Z					biological_process											owl:Class	
GO:0070943	biolink:NamedThing	neutrophil-mediated killing of symbiont cell	The directed killing of a symbiont target cell by a neutrophil. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	neutrophil mediated killing of symbiont cell							mah	2009-10-01T01:52:03Z					biological_process											owl:Class	
GO:1904705	biolink:NamedThing	regulation of vascular associated smooth muscle cell proliferation	Any process that modulates the frequency, rate or extent of vascular smooth muscle cell proliferation.	tmpzr1t_l9r_go_relaxed.owl	regulation of vascular smooth muscle cell proliferation|regulation of VSMC proliferation							sl	2015-10-01T16:05:20Z					biological_process											owl:Class	
GO:1990874	biolink:NamedThing	vascular associated smooth muscle cell proliferation	The multiplication or reproduction of vascular smooth muscle cells, resulting in the expansion of a cell population. A vascular smooth muscle cell is a non-striated, elongated, spindle-shaped cell found lining the blood vessels.	tmpzr1t_l9r_go_relaxed.owl	vascular smooth muscle cell proliferation|VSMC proliferation							sl	2015-09-29T16:34:59Z					biological_process											owl:Class	
GO:0071573	biolink:NamedThing	shelterin complex assembly	The aggregation, arrangement and bonding together of a set of components to form a shelterin complex. A shelterin complex is a nuclear telomere cap complex that is formed by the association of telomeric ssDNA- and dsDNA-binding proteins with telomeric DNA, and is involved in telomere protection and recruitment of telomerase.	tmpzr1t_l9r_go_relaxed.owl	shelterin complex formation|Pot1-Tpz1 complex assembly|telosome assembly|Pot1 complex assembly							mah	2010-01-26T01:45:20Z					biological_process											owl:Class	
GO:0032200	biolink:NamedThing	telomere organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of telomeres, terminal regions of a linear chromosome that include the telomeric DNA repeats and associated proteins.	tmpzr1t_l9r_go_relaxed.owl	telomere organisation|telomere organization and biogenesis|organization of chromosome, telomeric region|chromosome organization, telomeric													biological_process											owl:Class	
GO:0098686	biolink:NamedThing	hippocampal mossy fiber to CA3 synapse	One of the giant synapses that form between the mossy fiber axons of dentate gyrus granule cells and the large complex spines of CA3 pyramidal cells. It consists of a giant bouton known as the mossy fiber expansion, synapsed to the complex, multiheaded spine (thorny excresence) of a CA3 pyramidal cell.	tmpzr1t_l9r_go_relaxed.owl								dos	2017-02-05T16:29:58Z					cellular_component											owl:Class	
GO:0097464	biolink:NamedThing	thorny excrescence	Large complex spine protruding from a dendrite. Each excrescence is formed by a cluster of spine heads.	tmpzr1t_l9r_go_relaxed.owl					NIF_Subcellular:nlx_467			pr	2012-12-21T08:00:13Z					cellular_component											owl:Class	
GO:0061459	biolink:NamedThing	L-arginine transmembrane transporter activity	Enables the transfer of L-arginine from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	arginine-importing ATPase activity|ATPase-coupled L-arginine transmembrane transporter activity|arginine permease activity|arginine porter activity|arginine transmembrane transporter activity|histidine/arginine/lysine/ornithine porter activity|L-arginine transporter activity|ATP-dependent L-arginine transmembrane transporter activity|L-arginine-importing ATPase activity	https://github.com/geneontology/go-ontology/issues/22228			RHEA:32143			dph	2012-09-25T08:37:29Z			GO:0015181|GO:0102022|GO:0015598|GO:0005288		molecular_function											owl:Class	
GO:0120103	biolink:NamedThing	centriolar subdistal appendage	A protein complex which assembles on the mother centriole during cilium formation, adjacent and proximal to a centriolar distal appendage. In human, it contains ODF2, CNTRL, NIN, CCDC120c and CCDC68.	tmpzr1t_l9r_go_relaxed.owl	subdistal appendage of basal body|subdistal appendage of mother centriole|subdistal appendage of centriole							krc	2017-10-10T15:31:40Z					cellular_component											owl:Class	
GO:0005929	biolink:NamedThing	cilium	A specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface and of some cytoplasmic parts. Each cilium is largely bounded by an extrusion of the cytoplasmic (plasma) membrane, and contains a regular longitudinal array of microtubules, anchored to a basal body.	tmpzr1t_l9r_go_relaxed.owl	microtubule-based flagellum|eukaryotic flagellum|flagellum|primary cilium				FMA:67181|Wikipedia:Cilium|NIF_Subcellular:sao787716553	Note that we deem cilium and microtubule-based flagellum to be equivalent. In most eukaryotic species, intracellular sub-components of the cilium, such as the ciliary base and rootlet, are located near the plasma membrane. In Diplomonads such as Giardia, instead, the same ciliary parts are located further intracellularly. Also, 'cilium' may be used when axonemal structure and/or motility are unknown, or when axonemal structure is unusual. For all other cases, please refer to children of 'cilium'. Finally, note that any role of ciliary proteins in sensory events should be captured by annotating to relevant biological process terms.						GO:0072372		cellular_component											owl:Class	
GO:1901219	biolink:NamedThing	regulation of cardiac chamber morphogenesis	Any process that modulates the frequency, rate or extent of cardiac chamber morphogenesis.	tmpzr1t_l9r_go_relaxed.owl	regulation of heart chamber morphogenesis							rl	2012-08-06T17:59:11Z					biological_process											owl:Class	
GO:0003206	biolink:NamedThing	cardiac chamber morphogenesis	The process in which a cardiac chamber is generated and organized. A cardiac chamber is an enclosed cavity within the heart.	tmpzr1t_l9r_go_relaxed.owl	heart chamber morphogenesis							dph	2009-10-13T09:14:51Z					biological_process											owl:Class	
GO:0045056	biolink:NamedThing	transcytosis	The directed movement of endocytosed material through the cell and its exocytosis from the plasma membrane at the opposite side.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Transcytosis									biological_process											owl:Class	
GO:1903186	biolink:NamedThing	regulation of vitellogenesis	Any process that modulates the frequency, rate or extent of vitellogenesis.	tmpzr1t_l9r_go_relaxed.owl	regulation of yolk production							mr	2014-07-14T19:28:00Z					biological_process											owl:Class	
GO:0007296	biolink:NamedThing	vitellogenesis	The production of yolk. Yolk is a mixture of materials used for embryonic nutrition.	tmpzr1t_l9r_go_relaxed.owl	yolk production|yolk formation				Wikipedia:Vitellogenesis									biological_process											owl:Class	
GO:1902305	biolink:NamedThing	regulation of sodium ion transmembrane transport	Any process that modulates the frequency, rate or extent of sodium ion transmembrane transport.	tmpzr1t_l9r_go_relaxed.owl	regulation of sodium ion membrane transport							rl	2013-07-18T13:33:53Z					biological_process											owl:Class	
GO:0035725	biolink:NamedThing	sodium ion transmembrane transport	A process in which a sodium ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	sodium ion membrane transport					Note that this term is not intended for use in annotating lateral movement within membranes.		bf	2011-03-10T02:52:36Z					biological_process											owl:Class	
GO:0048721	biolink:NamedThing	clypeus morphogenesis	The process in which the anatomical structures of the clypeus are generated and organized.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0048723	biolink:NamedThing	clypeus development	The process whose specific outcome is the progression of the clypeus over time, from its formation to the mature structure. The clypeus is the shield-shaped plate on an insect's head.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0014011	biolink:NamedThing	Schwann cell proliferation involved in axon regeneration	The multiplication or reproduction of Schwann cells by cell division, resulting in the expansion of their population in response to an axonal lesion. The newly generated Schwann cells support subsequent axon regeneration in the peripheral nervous system.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1903666	biolink:NamedThing	positive regulation of asexual reproduction	Any process that activates or increases the frequency, rate or extent of asexual reproduction.	tmpzr1t_l9r_go_relaxed.owl	activation of asexual reproduction|up-regulation of asexual reproduction|upregulation of asexual reproduction|up regulation of asexual reproduction							pf	2014-11-26T21:13:40Z					biological_process											owl:Class	
GO:0097579	biolink:NamedThing	extracellular sequestering of copper ion	The process of binding or confining copper ions in an extracellular area such that they are separated from other components of a biological system.	tmpzr1t_l9r_go_relaxed.owl	extracellular sequestration of copper ion|extracellular storage of copper ion|extracellular copper ion retention|extracellular copper ion sequestration|extracellular retention of copper ion|extracellular copper ion sequestering|extracellular copper ion storage							pr	2014-02-28T11:18:04Z					biological_process											owl:Class	
GO:0006878	biolink:NamedThing	cellular copper ion homeostasis	Any process involved in the maintenance of an internal steady state of copper ions at the level of a cell.	tmpzr1t_l9r_go_relaxed.owl	copper homeostasis													biological_process											owl:Class	
GO:0002377	biolink:NamedThing	immunoglobulin production	The appearance of immunoglobulin due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	tmpzr1t_l9r_go_relaxed.owl	antibody production|immunoglobulin biosynthetic process|immunoglobulin secretion					Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.						GO:0048305|GO:0002378		biological_process											owl:Class	
GO:0071048	biolink:NamedThing	nuclear retention of unspliced pre-mRNA at the site of transcription	The process involved in retention of incorrectly or incompletely spliced pre-mRNA within the nucleus at the site of transcription.	tmpzr1t_l9r_go_relaxed.owl								krc	2009-08-11T02:19:03Z					biological_process											owl:Class	
GO:0071030	biolink:NamedThing	nuclear mRNA surveillance of spliceosomal pre-mRNA splicing	The set of processes involved in identifying and degrading incorrectly spliced pre-mRNAs within the nucleus.	tmpzr1t_l9r_go_relaxed.owl	nuclear RNA catabolic process of incorrectly spliced pre-mRNA|nuclear mRNA quality control of incorrectly spliced pre-mRNA							krc	2009-07-28T04:24:04Z					biological_process											owl:Class	
GO:0003069	biolink:NamedThing	acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure	The process in which acetylcholine signaling causes vasodilation, resulting in a change in blood pressure.	tmpzr1t_l9r_go_relaxed.owl	vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure													biological_process											owl:Class	
GO:0038027	biolink:NamedThing	apolipoprotein A-I-mediated signaling pathway	A series of molecular signals initiated by the binding of apolipoprotein A-I to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.	tmpzr1t_l9r_go_relaxed.owl	apolipoprotein A-I-mediated signalling pathway							bf	2011-08-02T02:13:41Z					biological_process											owl:Class	
GO:1902183	biolink:NamedThing	regulation of shoot apical meristem development	Any process that modulates the frequency, rate or extent of shoot apical meristem development.	tmpzr1t_l9r_go_relaxed.owl	regulation of promeristem development|regulation of SAM development|regulation of primary shoot meristem development							tb	2013-05-31T16:33:55Z					biological_process											owl:Class	
GO:1990674	biolink:NamedThing	Golgi cis cisterna membrane	The lipid bilayer surrounding any of the thin, flattened compartments that form the cis portion of the Golgi complex.	tmpzr1t_l9r_go_relaxed.owl	cis-Golgi cisterna membrane							bhm	2015-03-02T11:48:00Z					cellular_component											owl:Class	
GO:0000137	biolink:NamedThing	Golgi cis cisterna	The Golgi cisterna closest to the endoplasmic reticulum; the first processing compartment through which proteins pass after export from the ER.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:1900624	biolink:NamedThing	negative regulation of monocyte aggregation	Any process that stops, prevents or reduces the frequency, rate or extent of monocyte aggregation.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of mononuclear phagocyte aggregation|downregulation of monocyte aggregation|downregulation of mononuclear phagocyte aggregation|negative regulation of mononuclear phagocyte aggregation|inhibition of mononuclear phagocyte aggregation|inhibition of monocyte aggregation|down-regulation of monocyte aggregation|down regulation of monocyte aggregation|down regulation of mononuclear phagocyte aggregation							vk	2012-05-21T01:07:37Z					biological_process											owl:Class	
GO:0070487	biolink:NamedThing	monocyte aggregation	The adhesion of one monocyte to one or more other monocytes via adhesion molecules.	tmpzr1t_l9r_go_relaxed.owl	mononuclear phagocyte aggregation													biological_process											owl:Class	
GO:0051627	biolink:NamedThing	negative regulation of epinephrine uptake	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of epinephrine into a cell.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of adrenaline uptake|down-regulation of epinephrine uptake|down regulation of epinephrine uptake|negative regulation of epinephrine import|downregulation of epinephrine uptake													biological_process											owl:Class	
GO:0051625	biolink:NamedThing	epinephrine uptake	The directed movement of epinephrine into a cell, typically presynaptic neurons or glial cells. Epinephrine is a hormone produced by the medulla of the adrenal glands that increases heart activity, improves the power and prolongs the action of muscles, and increases the rate and depth of breathing. It is synthesized by the methylation of norepinephrine.	tmpzr1t_l9r_go_relaxed.owl	adrenaline uptake|adrenaline reuptake|epinephrine import|epinephrine reuptake													biological_process											owl:Class	
GO:0071015	biolink:NamedThing	U12-type prespliceosome	A spliceosomal complex that is formed by the cooperative binding of the heterodimeric U11/U12 snRNP to the 5' splice site and the branch point sequence. The U12-type prespliceosome includes many proteins in addition to those found in the U11/U12 heterodimeric snRNPs. Commitment to a given pair of 5' and 3' splice sites occurs at the time of prespliceosome formation.	tmpzr1t_l9r_go_relaxed.owl	minor prespliceosome|mammalian U12-type spliceosomal complex A|yeast U12-type spliceosomal complex B|AT-AC prespliceosome							mah	2009-07-30T12:00:35Z					cellular_component											owl:Class	
GO:1905128	biolink:NamedThing	positive regulation of axo-dendritic protein transport	Any process that activates or increases the frequency, rate or extent of axo-dendritic protein transport.	tmpzr1t_l9r_go_relaxed.owl	up regulation of axonal protein transport|up-regulation of axo-dendritic protein transport|upregulation of axo-dendritic protein transport|up regulation of axo-dendritic protein transport|upregulation of axonal protein transport|activation of axo-dendritic protein transport|up-regulation of axonal protein transport|activation of axonal protein transport|positive regulation of axonal protein transport							sl	2016-04-11T20:38:48Z					biological_process											owl:Class	
GO:1905292	biolink:NamedThing	regulation of neural crest cell differentiation	Any process that modulates the frequency, rate or extent of neural crest cell differentiation.	tmpzr1t_l9r_go_relaxed.owl								rl	2016-06-28T15:02:01Z					biological_process											owl:Class	
GO:0034505	biolink:NamedThing	tooth mineralization	The process in which calcium salts are deposited into calcareous tooth structures such as dental enamel, dentin and cementum.	tmpzr1t_l9r_go_relaxed.owl	tooth calcification													biological_process											owl:Class	
GO:1900690	biolink:NamedThing	negative regulation of gliotoxin biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of gliotoxin biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of gliotoxin biosynthesis|down regulation of gliotoxin formation|negative regulation of gliotoxin synthesis|negative regulation of gliotoxin formation|inhibition of gliotoxin synthesis|inhibition of gliotoxin anabolism|down-regulation of gliotoxin formation|down regulation of gliotoxin biosynthetic process|inhibition of gliotoxin biosynthesis|down-regulation of gliotoxin anabolism|inhibition of gliotoxin formation|down-regulation of gliotoxin biosynthetic process|downregulation of gliotoxin synthesis|down-regulation of gliotoxin synthesis|downregulation of gliotoxin biosynthesis|down-regulation of gliotoxin biosynthesis|down regulation of gliotoxin anabolism|down regulation of gliotoxin biosynthesis|down regulation of gliotoxin synthesis|inhibition of gliotoxin biosynthetic process|negative regulation of gliotoxin anabolism|downregulation of gliotoxin biosynthetic process|downregulation of gliotoxin formation|downregulation of gliotoxin anabolism							di	2012-05-22T04:52:00Z					biological_process											owl:Class	
GO:0010452	biolink:NamedThing	histone H3-K36 methylation	The modification of histone H3 by addition of one or more methyl groups to lysine at position 36 of the histone.	tmpzr1t_l9r_go_relaxed.owl	histone lysine H3 K36 methylation|histone H3K36me|histone H3 K36 methylation													biological_process											owl:Class	
GO:0061552	biolink:NamedThing	ganglion morphogenesis	The process in which the anatomical structures of ganglion are generated and organized.	tmpzr1t_l9r_go_relaxed.owl	ganglia morphogenesis							dph	2013-07-10T08:44:57Z					biological_process											owl:Class	
GO:0061548	biolink:NamedThing	ganglion development	The process whose specific outcome is the progression of a ganglion over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl	gangliogenesis|ganglia development							dph	2013-07-10T08:36:12Z					biological_process											owl:Class	
GO:0035402	biolink:NamedThing	histone kinase activity (H3-T11 specific)	Catalysis of the transfer of a phosphate group to the threonine-11 residue of the N-terminal tail of histone H3.	tmpzr1t_l9r_go_relaxed.owl	histone threonine kinase activity (H3-T11 specific)|histone-threonine kinase activity (H3-T11 specific)							bf	2010-03-24T10:04:40Z					molecular_function											owl:Class	
GO:0035407	biolink:NamedThing	histone H3-T11 phosphorylation	The modification of histone H3 by the addition of an phosphate group to a threonine residue at position 11 of the histone.	tmpzr1t_l9r_go_relaxed.owl								bf	2010-03-24T10:12:01Z					biological_process											owl:Class	
GO:0071915	biolink:NamedThing	protein-lysine lysylation	The addition of lysine group to a lysine residue in a protein, producing N6-(lysyl)-L-lysine. This modification is observed in, and is probably unique to, translation elongation factor P (EF-P).	tmpzr1t_l9r_go_relaxed.owl	protein amino acid lysylation							mah	2010-09-24T10:01:57Z					biological_process											owl:Class	
GO:0007432	biolink:NamedThing	salivary gland boundary specification	Determination of where the salivary gland forms, the total number of salivary gland cells and how many cells are allocated to each of the specialised cell types within the salivary gland.	tmpzr1t_l9r_go_relaxed.owl	salivary gland determination													biological_process											owl:Class	
GO:0032615	biolink:NamedThing	interleukin-12 production	The appearance of interleukin-12 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	tmpzr1t_l9r_go_relaxed.owl	IL-12 production|CLMF production|interleukin-12 biosynthetic process|interleukin-12 secretion|NKSF production											GO:0072610|GO:0042090		biological_process											owl:Class	
GO:0047145	biolink:NamedThing	demethylsterigmatocystin 6-O-methyltransferase activity	Catalysis of the reaction: 6-demethylsterigmatocystin + S-adenosyl-L-methionine = sterigmatocystin + S-adenosyl-homocysteine.	tmpzr1t_l9r_go_relaxed.owl	demethylsterigmatocystin methyltransferase activity|O-methyltransferase I|S-adenosyl-L-methionine:6-demethylsterigmatocystin 6-O-methyltransferase activity				EC:2.1.1.109|RHEA:11504|MetaCyc:2.1.1.109-RXN									molecular_function											owl:Class	
GO:0098839	biolink:NamedThing	postsynaptic density membrane	The membrane component of the postsynaptic density. This is the region of the postsynaptic membrane in which the population of neurotransmitter receptors involved in synaptic transmission are concentrated.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0036466	biolink:NamedThing	synaptic vesicle recycling via endosome	Synaptic vesicle recycling where vesicles endocytosed via clathrin-coated pits re-acidify and refill with neurotransmitters after passing through an endosomal intermediate.	tmpzr1t_l9r_go_relaxed.owl	recycling endosome localization within postsynapse							bf	2014-06-26T11:07:46Z			GO:0099090		biological_process											owl:Class	
GO:0045916	biolink:NamedThing	negative regulation of complement activation	Any process that stops, prevents, or reduces the frequency, rate or extent of complement activation.	tmpzr1t_l9r_go_relaxed.owl	down regulation of complement activation|negative regulation of complement cascade|downregulation of complement activation|inhibition of complement activation|down-regulation of complement activation													biological_process											owl:Class	
GO:0071242	biolink:NamedThing	cellular response to ammonium ion	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ammonium stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to ammonia							mah	2009-12-03T02:39:40Z			GO:1903718		biological_process											owl:Class	
GO:0060601	biolink:NamedThing	lateral sprouting from an epithelium	The process in which a branch forms along the side of an epithelium.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-05-14T02:33:01Z					biological_process											owl:Class	
GO:1901843	biolink:NamedThing	positive regulation of high voltage-gated calcium channel activity	Any process that activates or increases the frequency, rate or extent of high voltage-gated calcium channel activity.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of high voltage gated calcium channel activity|upregulation of high voltage-gated calcium channel activity|up regulation of high voltage-dependent calcium channel activity|up-regulation of high voltage-dependent calcium channel activity|upregulation of high voltage gated calcium channel activity|up-regulation of high voltage gated calcium channel activity|up-regulation of high voltage-gated calcium channel activity|activation of high voltage-dependent calcium channel activity|upregulation of high voltage-dependent calcium channel activity|activation of high voltage-gated calcium channel activity|up regulation of high voltage-gated calcium channel activity|activation of high voltage gated calcium channel activity|up regulation of high voltage gated calcium channel activity|positive regulation of high voltage-dependent calcium channel activity							rl	2013-01-24T19:02:25Z					biological_process											owl:Class	
GO:0008331	biolink:NamedThing	high voltage-gated calcium channel activity	Enables the transmembrane transfer of a calcium ion by a high voltage-gated channel. A high voltage-gated channel is a channel whose open state is dependent on high voltage across the membrane in which it is embedded.	tmpzr1t_l9r_go_relaxed.owl	high voltage gated calcium channel activity|high voltage-dependent calcium channel activity|P-type calcium channel|L-type calcium channel|N-type calcium channel|Q-type calcium channel													molecular_function											owl:Class	
GO:0021649	biolink:NamedThing	vestibulocochlear nerve structural organization	The process that contributes to the act of creating the structural organization of the vestibulocochlear nerve. This process pertains to the physical shaping of a rudimentary structure. This sensory nerve innervates the membranous labyrinth of the inner ear. The vestibular branch innervates the vestibular apparatus that senses head position changes relative to gravity. The auditory branch innervates the cochlear duct, which is connected to the three bony ossicles which transduce sound waves into fluid movement in the cochlea.	tmpzr1t_l9r_go_relaxed.owl	vestibulocochlear nerve structural organisation|CN VII structural organization													biological_process											owl:Class	
GO:0021648	biolink:NamedThing	vestibulocochlear nerve morphogenesis	The process in which the anatomical structure of the vestibulocochlear nerve is generated and organized. This sensory nerve innervates the membranous labyrinth of the inner ear. The vestibular branch innervates the vestibular apparatus that senses head position changes relative to gravity. The auditory branch innervates the cochlear duct, which is connected to the three bony ossicles which transduce sound waves into fluid movement in the cochlea.	tmpzr1t_l9r_go_relaxed.owl	CN VIII morphogenesis													biological_process											owl:Class	
GO:0060396	biolink:NamedThing	growth hormone receptor signaling pathway	The series of molecular signals generated as a consequence of growth hormone receptor binding to its physiological ligand.	tmpzr1t_l9r_go_relaxed.owl	growth hormone receptor signalling pathway|GH receptor signaling pathway|cellular response to growth hormone													biological_process											owl:Class	
GO:0072256	biolink:NamedThing	metanephric glomerular mesangial cell fate commitment	The process in which the developmental fate of a cell becomes restricted such that it will develop into a metanephric glomerular mesangial cell.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-03-19T04:07:10Z					biological_process											owl:Class	
GO:0072254	biolink:NamedThing	metanephric glomerular mesangial cell differentiation	The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the glomerular mesangial cells of the metanephros as it progresses from its formation to the mature state.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-03-19T04:04:02Z					biological_process											owl:Class	
GO:0060856	biolink:NamedThing	establishment of blood-brain barrier	Establishment of the barrier between the blood and the brain. The cells in the brain are packed tightly together preventing the passage of most molecules from the blood into the brain. Only lipid soluble molecules or those that are actively transported can pass through the blood-brain barrier.	tmpzr1t_l9r_go_relaxed.owl	establishment of BBB|establishment of blood/brain barrier							dph	2009-08-12T12:12:59Z					biological_process											owl:Class	
GO:0007417	biolink:NamedThing	central nervous system development	The process whose specific outcome is the progression of the central nervous system over time, from its formation to the mature structure. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain and spinal cord. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord.	tmpzr1t_l9r_go_relaxed.owl	CNS development				Wikipedia:Neural_development									biological_process											owl:Class	
GO:0021821	biolink:NamedThing	negative regulation of cell-glial cell adhesion involved in cerebral cortex lamination	The process that results in the release of migrating cells from their interaction with radial glial cells as a component of the process of cerebral cortex glial-mediated radial cell migration.	tmpzr1t_l9r_go_relaxed.owl	downregulation of cell-glial cell adhesion involved in cerebral cortex lamination|inhibition of cell-glial cell adhesion involved in cerebral cortex lamination|down-regulation of cell-glial cell adhesion involved in cerebral cortex lamination|down regulation of cell-glial cell adhesion involved in cerebral cortex lamination													biological_process											owl:Class	
GO:0021819	biolink:NamedThing	layer formation in cerebral cortex	The detachment of cells from radial glial fibers at the appropriate time when they cease to migrate and form distinct layer in the cerebral cortex.	tmpzr1t_l9r_go_relaxed.owl	cerebral cortex lamination													biological_process											owl:Class	
GO:1904955	biolink:NamedThing	planar cell polarity pathway involved in midbrain dopaminergic neuron differentiation	Any Wnt signaling pathway, planar cell polarity pathway that is involved in midbrain dopaminergic neuron differentiation.	tmpzr1t_l9r_go_relaxed.owl	Wnt-JNK signaling pathway involved in midbrain DA neurogenesis|Wnt-PCP signaling pathway involved in midbrain dopaminergic neuron production|PCP pathway involved in midbrain dopaminergic neuron production|Wnt receptor signalling pathway, planar cell polarity pathway involved in midbrain dopaminergic neuron production|non-canonical Wnt signaling pathway involved in midbrain DA neurogenesis|PCP pathway involved in DA neurogenesis from midbrain floor plate|Wnt-JNK signaling pathway involved in mDA neuron differentiation|Wnt signaling pathway, planar cell polarity pathway involved in DA neurogenesis from midbrain floor plate|Wnt receptor signalling pathway, planar cell polarity pathway involved in DA neurogenesis from midbrain floor plate|Wnt receptor signalling pathway, planar cell polarity pathway involved in midbrain dopaminergic neuron differentiation|Wnt-PCP signaling pathway involved in midbrain dopaminergic neuron differentiation|Wnt receptor signaling pathway, planar cell polarity pathway involved in midbrain dopaminergic neuron differentiation|Wnt receptor signaling pathway, planar cell polarity pathway involved in mDA neuron differentiation|PCP pathway involved in midbrain dopaminergic neuron differentiation|non-canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation|non-canonical Wnt-mediated midbrain DA neuron differentiation|Wnt-PCP signaling pathway involved in mDA neuron differentiation|non-canonical Wnt signaling pathway involved in midbrain dopaminergic neuron production|non-canonical Wnt signaling pathway involved in mDA neuron differentiation|Wnt receptor signalling pathway, planar cell polarity pathway involved in midbrain DA neurogenesis|Wnt-PCP signaling pathway involved in midbrain DA neurogenesis|Wnt-activated signaling pathway, planar cell polarity pathway involved in midbrain dopaminergic neuron differentiation|Wnt-JNK signaling pathway involved in midbrain dopaminergic neuron production|PCP pathway involved in midbrain DA neurogenesis|Wnt signaling pathway, planar cell polarity pathway involved in mDA neuron differentiation|Wnt-activated signaling pathway, planar cell polarity pathway involved in DA neurogenesis from midbrain floor plate|PCP pathway involved in mDA neuron differentiation|planar cell polarity pathway involved in midbrain dopaminergic neuron production|planar cell polarity pathway involved in DA neurogenesis from midbrain floor plate|Wnt-JNK signaling pathway involved in DA neurogenesis from midbrain floor plate|Wnt receptor signaling pathway, planar cell polarity pathway involved in midbrain DA neurogenesis|Wnt receptor signaling pathway, planar cell polarity pathway involved in midbrain dopaminergic neuron production|Wnt-JNK signaling pathway involved in midbrain dopaminergic neuron differentiation|Wnt-activated signaling pathway, planar cell polarity pathway involved in midbrain dopaminergic neuron production|Wnt-activated signaling pathway, planar cell polarity pathway involved in mDA neuron differentiation|Wnt signaling pathway, planar cell polarity pathway involved in midbrain dopaminergic neuron production|non-canonical Wnt signaling pathway involved in DA neurogenesis from midbrain floor plate|Wnt-activated signaling pathway, planar cell polarity pathway involved in midbrain DA neurogenesis|planar cell polarity pathway involved in midbrain DA neurogenesis|Wnt signaling pathway, planar cell polarity pathway involved in midbrain dopaminergic neuron differentiation|Wnt receptor signalling pathway, planar cell polarity pathway involved in mDA neuron differentiation|planar cell polarity pathway involved in mDA neuron differentiation|Wnt-PCP signaling pathway involved in DA neurogenesis from midbrain floor plate|Wnt signaling pathway, planar cell polarity pathway involved in midbrain DA neurogenesis|Wnt receptor signaling pathway, planar cell polarity pathway involved in DA neurogenesis from midbrain floor plate							bf	2016-02-09T11:04:56Z					biological_process											owl:Class	
GO:1904948	biolink:NamedThing	midbrain dopaminergic neuron differentiation	The process in which a relatively unspecialized cell acquires the specialized features of a midbrain dopaminergic neuron.	tmpzr1t_l9r_go_relaxed.owl	DA neurogenesis from midbrain floor plate|midbrain dopaminergic neuron production|midbrain DA neurogenesis|mDA neuron differentiation							bf	2016-02-04T14:38:10Z					biological_process											owl:Class	
GO:1901966	biolink:NamedThing	regulation of cellular response to iron ion starvation	Any process that modulates the frequency, rate or extent of cellular response to iron ion starvation.	tmpzr1t_l9r_go_relaxed.owl								al	2013-02-21T11:35:57Z					biological_process											owl:Class	
GO:0034442	biolink:NamedThing	regulation of lipoprotein oxidation	Any process that modulates the frequency, rate or extent of lipoprotein oxidation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0042161	biolink:NamedThing	lipoprotein oxidation	The modification of a lipoprotein by oxidation of one or more amino acids or the lipid group.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:2000316	biolink:NamedThing	regulation of T-helper 17 type immune response	Any process that modulates the frequency, rate or extent of T-helper 17 type immune response.	tmpzr1t_l9r_go_relaxed.owl	regulation of Th17 immune response							mah	2011-01-18T01:32:26Z					biological_process											owl:Class	
GO:0072538	biolink:NamedThing	T-helper 17 type immune response	An immune response which is associated with resistance to intracellular bacteria with a key role in inflammation and tissue injury. This immune response is associated with pathological autoimmune conditions such as multiple sclerosis, arthritis and psoriasis which is typically orchestrated by the production of particular cytokines by T-helper 17 cells, most notably interleukin-17, IL-21 and IL-22.	tmpzr1t_l9r_go_relaxed.owl	Th17 immune response							mah	2011-01-17T11:13:53Z					biological_process											owl:Class	
GO:0048263	biolink:NamedThing	determination of dorsal identity	Determination of the identity of part of an organism or organ where those parts are of the type that occur in the dorsal region. Identity is considered to be the aggregate of characteristics by which a structure is recognized.	tmpzr1t_l9r_go_relaxed.owl	determination of adaxial identity													biological_process											owl:Class	
GO:0048262	biolink:NamedThing	determination of dorsal/ventral asymmetry	Determination of asymmetry from the dorsal to the ventral side; as, the dorsoventral axis.	tmpzr1t_l9r_go_relaxed.owl	determination of dorsal-ventral asymmetry|determination of dorsoventral asymmetry|determination of adaxial/abaxial asymmetry													biological_process											owl:Class	
GO:0097495	biolink:NamedThing	H-NS-Hha complex	A trimeric protein complex made up of an H-NS homodimer and an Hha monomer. In Enterobacteriaceae, this complex negatively regulates transcription of a range of genes.	tmpzr1t_l9r_go_relaxed.owl								pr	2013-08-08T14:37:33Z					cellular_component											owl:Class	
GO:0015616	biolink:NamedThing	DNA translocase activity	Generation of movement along a single- or double-stranded DNA molecule, driven by ATP hydrolysis.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/21612				Note that some gene products that possess DNA translocase activity, such as members of the FtsK/SpoIIIE family, can be fixed in place by interactions with other components of the cell; the relative movement between the protein and DNA bound to it results in movement of the DNA within the cell, often across a membrane.								molecular_function											owl:Class	
GO:2000929	biolink:NamedThing	positive regulation of cellodextrin catabolic process	Any process that activates or increases the frequency, rate or extent of cellodextrin catabolic process.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of cellodextrin catabolism							tt	2011-08-01T12:41:36Z					biological_process											owl:Class	
GO:0060114	biolink:NamedThing	vestibular receptor cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a vestibular hair cell.	tmpzr1t_l9r_go_relaxed.owl	vestibular hair cell differentiation													biological_process											owl:Class	
GO:0150019	biolink:NamedThing	basal dendrite morphogenesis	The process in which the anatomical structures of a basal dendrite are generated and organized.	tmpzr1t_l9r_go_relaxed.owl								bc	2017-12-22T11:26:07Z					biological_process											owl:Class	
GO:0150018	biolink:NamedThing	basal dendrite development	The process whose specific outcome is the progression of a basal dendrite over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl								bc	2017-12-22T11:09:53Z					biological_process											owl:Class	
GO:0036366	biolink:NamedThing	transforming growth factor beta3 activation	The release of transforming growth factor beta 3 (TGF-beta3) from its latent state.	tmpzr1t_l9r_go_relaxed.owl	TGFbeta 3 activation|TGFB3 activation|TGF-beta 3 activation							bf	2012-09-24T10:16:05Z					biological_process											owl:Class	
GO:0032907	biolink:NamedThing	transforming growth factor beta3 production	The appearance of transforming growth factor-beta3 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	tmpzr1t_l9r_go_relaxed.owl	TGF-B3 production|transforming growth factor-beta3 production|TGFB3 production													biological_process											owl:Class	
GO:0070175	biolink:NamedThing	positive regulation of enamel mineralization	Any process that activates or increases the frequency, rate or extent of enamel mineralization, the deposition of calcium salts in tooth enamel.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0070166	biolink:NamedThing	enamel mineralization	The process in which calcium salts, mainly carbonated hydroxyapatite, are deposited in tooth enamel.	tmpzr1t_l9r_go_relaxed.owl	enamel formation													biological_process											owl:Class	
GO:0001541	biolink:NamedThing	ovarian follicle development	The process whose specific outcome is the progression of the ovarian follicle over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl	follicular phase													biological_process											owl:Class	
GO:0099582	biolink:NamedThing	neurotransmitter receptor activity involved in regulation of presynaptic cytosolic calcium ion concentration	Any neurotransmitter receptor activity that is involved in regulating the concentration of calcium in the presynaptic cytosol.	tmpzr1t_l9r_go_relaxed.owl	neurotransmitter receptor activity involved in regulation of presynaptic cytosolic calcium levels													molecular_function											owl:Class	
GO:0042734	biolink:NamedThing	presynaptic membrane	A specialized area of membrane of the axon terminal that faces the plasma membrane of the neuron or muscle fiber with which the axon terminal establishes a synaptic junction; many synaptic junctions exhibit structural presynaptic characteristics, such as conical, electron-dense internal protrusions, that distinguish it from the remainder of the axon plasma membrane.	tmpzr1t_l9r_go_relaxed.owl	pre-synaptic membrane|presynaptic plasma membrane													cellular_component											owl:Class	
GO:0060413	biolink:NamedThing	atrial septum morphogenesis	The developmental process in which atrial septum is generated and organized. The atrial septum separates the upper chambers (the atria) of the heart from one another.	tmpzr1t_l9r_go_relaxed.owl	interatrial septum morphogenesis											GO:0003287		biological_process											owl:Class	
GO:0003283	biolink:NamedThing	atrial septum development	The progression of the atrial septum over time, from its initial formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-10-20T10:10:38Z					biological_process											owl:Class	
GO:0048566	biolink:NamedThing	embryonic digestive tract development	The process whose specific outcome is the progression of the gut over time, from its formation to the mature structure during embryonic development. The gut is the region of the digestive tract extending from the beginning of the intestines to the anus.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0060136	biolink:NamedThing	embryonic process involved in female pregnancy	A reproductive process occurring in the embryo or fetus that allows the embryo or fetus to develop within the mother.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0009790	biolink:NamedThing	embryo development	The process whose specific outcome is the progression of an embryo from its formation until the end of its embryonic life stage. The end of the embryonic stage is organism-specific. For example, for mammals, the process would begin with zygote formation and end with birth. For insects, the process would begin at zygote formation and end with larval hatching. For plant zygotic embryos, this would be from zygote formation to the end of seed dormancy. For plant vegetative embryos, this would be from the initial determination of the cell or group of cells to form an embryo until the point when the embryo becomes independent of the parent plant.	tmpzr1t_l9r_go_relaxed.owl	embryogenesis and morphogenesis|embryonal development|embryogenesis				Wikipedia:Embryogenesis							GO:0009795		biological_process											owl:Class	
GO:0010602	biolink:NamedThing	regulation of 1-aminocyclopropane-1-carboxylate metabolic process	Regulation of the chemical reactions and pathways involving 1-aminocyclopropane-1-carboxylate, the anion of 1-aminocyclopropane-1-carboxylic acid, a natural product found in plant tissues. It is a key intermediate in the biosynthesis of ethylene (ethene), a fruit-ripening hormone in plants.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0018871	biolink:NamedThing	1-aminocyclopropane-1-carboxylate metabolic process	The chemical reactions and pathways involving 1-aminocyclopropane-1-carboxylate, the anion of 1-aminocyclopropane-1-carboxylic acid, a natural product found in plant tissues. It is a key intermediate in the biosynthesis of ethylene (ethene), a fruit-ripening hormone in plants.	tmpzr1t_l9r_go_relaxed.owl	ACP metabolism|ACP metabolic process|1-aminocyclopropane-1-carboxylate metabolism				UM-BBD_pathwayID:acp									biological_process											owl:Class	
GO:0021835	biolink:NamedThing	chemoattraction involved in embryonic olfactory bulb interneuron precursor migration	The creation and reception of signals that result in the migration of interneuron precursors up a concentration gradient towards the olfactory bulb.	tmpzr1t_l9r_go_relaxed.owl	positive chemotaxis involved in embryonic olfactory bulb interneuron precursor migration													biological_process											owl:Class	
GO:0021831	biolink:NamedThing	embryonic olfactory bulb interneuron precursor migration	The directed movement of individual interneuron precursors during the embryonic development of the olfactory bulb.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:2001154	biolink:NamedThing	regulation of glycolytic fermentation to ethanol	Any process that modulates the frequency, rate or extent of glucose catabolic process to ethanol.	tmpzr1t_l9r_go_relaxed.owl	regulation of glucose fermentation to ethanol|regulation of ethanol fermentation							mcc	2011-10-27T02:39:00Z					biological_process											owl:Class	
GO:0019655	biolink:NamedThing	glycolytic fermentation to ethanol	The anaerobic chemical reactions and pathways resulting in the breakdown of glucose; it is converted into ethanol and carbon dioxide (CO2), producing two molecules of ATP for each molecule of glucose.	tmpzr1t_l9r_go_relaxed.owl	glucose catabolic process to ethanol|glucose fermentation to ethanol|ethanol fermentation|alcoholic fermentation				Wikipedia:Ethanol_fermentation									biological_process											owl:Class	
GO:1904728	biolink:NamedThing	positive regulation of replicative senescence	Any process that activates or increases the frequency, rate or extent of replicative senescence.	tmpzr1t_l9r_go_relaxed.owl	activation of replicative senescence|up regulation of replicative senescence|up-regulation of replicative senescence|upregulation of replicative senescence							rph	2015-10-14T13:11:37Z					biological_process											owl:Class	
GO:0090399	biolink:NamedThing	replicative senescence	A cell aging process associated with the dismantling of a cell as a response to telomere shortening and/or cellular aging.	tmpzr1t_l9r_go_relaxed.owl								tb	2011-01-05T02:32:29Z					biological_process											owl:Class	
GO:0002496	biolink:NamedThing	proteolysis associated with antigen processing and presentation	The hydrolysis of a peptide bond or bonds within a protein contributing to antigen processing and presentation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0051232	biolink:NamedThing	meiotic spindle elongation	The lengthening of the distance between poles of the spindle during a meiotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl	spindle elongation during meiosis													biological_process											owl:Class	
GO:0043971	biolink:NamedThing	histone H3-K18 acetylation	The modification of histone H3 by the addition of an acetyl group to a lysine residue at position 18 of the histone.	tmpzr1t_l9r_go_relaxed.owl	histone H3 acetylation at K18|histone H3K18 acetylation													biological_process											owl:Class	
GO:0007431	biolink:NamedThing	salivary gland development	The process whose specific outcome is the progression of the salivary gland over time, from its formation to the mature structure. Salivary glands include any of the saliva-secreting exocrine glands of the oral cavity.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:2000245	biolink:NamedThing	negative regulation of FtsZ-dependent cytokinesis	Any process that stops, prevents, or reduces the frequency, rate or extent of Ftsz-dependent cytokinesis.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of prokaryote-type cytokinesis|negative regulation of prokaryotic fission							mah	2010-11-10T02:46:39Z					biological_process											owl:Class	
GO:0043093	biolink:NamedThing	FtsZ-dependent cytokinesis	A cytokinesis process that involves a set of conserved proteins including FtsZ, and results in the formation of two similarly sized and shaped cells.	tmpzr1t_l9r_go_relaxed.owl	cytokinesis by binary fission|prokaryote-type cytokinesis|prokaryotic fission				Wikipedia:Binary_fission	Note that this term is intended for the annotation of prokaryotic gene products.								biological_process											owl:Class	
GO:1905115	biolink:NamedThing	regulation of lateral attachment of mitotic spindle microtubules to kinetochore	Any process that modulates the frequency, rate or extent of lateral attachment of mitotic spindle microtubules to kinetochore.	tmpzr1t_l9r_go_relaxed.owl								al	2016-04-07T14:25:25Z					biological_process											owl:Class	
GO:0099607	biolink:NamedThing	lateral attachment of mitotic spindle microtubules to kinetochore	The cell cycle process in which sister chromatids become laterally attached to spindle microtubules as part of mitotic metaphase plate congression. Attachment precedes migration along microtubules towards the spindle equator (metaphase plate).	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0061110	biolink:NamedThing	dense core granule biogenesis	A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a dense core granule. Includes biosynthesis of constituent macromolecules, and those macromolecular modifications that are involved in synthesis or assembly of the dense core granule.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-05-01T09:40:11Z					biological_process											owl:Class	
GO:1990156	biolink:NamedThing	DnaB-DnaG complex	A protein complex containing homohexameric DnaB helicase, and DnaG (a primase). Facilitates the unwinding of double-stranded DNA and the synthesis of RNA primer sequences during DNA replication and repair in Prokaryotes.	tmpzr1t_l9r_go_relaxed.owl	DnaB-DnaG primosome complex							bhm	2013-08-02T09:50:54Z					cellular_component											owl:Class	
GO:1990161	biolink:NamedThing	DnaB helicase complex	A homohexameric protein complex that possesses DNA helicase activity; functions during DNA replication and repair.	tmpzr1t_l9r_go_relaxed.owl	DnaB hexamer							bhm	2013-08-02T15:55:48Z					cellular_component											owl:Class	
GO:1905333	biolink:NamedThing	regulation of gastric motility	Any process that modulates the frequency, rate or extent of gastric motility.	tmpzr1t_l9r_go_relaxed.owl								als	2016-07-22T09:47:31Z					biological_process											owl:Class	
GO:0035482	biolink:NamedThing	gastric motility	The spontaneous peristaltic movements of the stomach that aid in digestion, moving food through the stomach and out through the pyloric sphincter into the duodenum.	tmpzr1t_l9r_go_relaxed.owl								bf	2010-04-23T10:44:59Z					biological_process											owl:Class	
GO:1901630	biolink:NamedThing	negative regulation of presynaptic membrane organization	Any process that stops, prevents or reduces the frequency, rate or extent of presynaptic membrane organization.	tmpzr1t_l9r_go_relaxed.owl	inhibition of presynaptic membrane organization|negative regulation of pre-synaptic membrane organization|negative regulation of presynaptic membrane organisation|down regulation of presynaptic membrane organization|down-regulation of presynaptic membrane organisation|down-regulation of presynaptic membrane organization|down regulation of presynaptic membrane organisation|inhibition of presynaptic membrane organisation|downregulation of presynaptic membrane organization|downregulation of presynaptic membrane organisation							ans	2012-11-15T11:40:36Z					biological_process											owl:Class	
GO:0097090	biolink:NamedThing	presynaptic membrane organization	A process which results in the assembly, arrangement of constituent parts, or disassembly of a presynaptic membrane, including any proteins associated with the membrane, but excluding other cellular components. A presynaptic membrane is a specialized area of membrane of the axon terminal that faces the plasma membrane of the neuron or muscle fiber with which the axon terminal establishes a synaptic junction.	tmpzr1t_l9r_go_relaxed.owl	pre-synaptic membrane organization|presynaptic membrane organisation					Note that 'presynaptic membrane' in this term should not be mistaken with 'presynaptic active zone'. The latter encompasses more than the former, as it also includes the specialized cortical cytoskeletal matrix in the cell cortex of a presynaptic neuron.		pr	2011-07-04T01:45:30Z					biological_process											owl:Class	
GO:1990689	biolink:NamedThing	endoplasmic reticulum-Golgi intermediate compartment (ERGIC) derived vesicle fusion with Golgi cis cisterna membrane	The joining of the lipid bilayer membrane around an ERGIC-derived vesicle to the lipid bilayer membrane around the Golgi cis cisterna. Such vesicles include COPII-coated transport vesicles involved in anterograde transport.	tmpzr1t_l9r_go_relaxed.owl	ERGIC-derived vesicle fusion with cis-Golgi cisterna membrane|ER-Golgi intermediate compartment derived vesicle fusion with cis-Golgi cisterna membrane|ER-Golgi intermediate compartment derived vesicle fusion with Golgi cis cisterna membrane|ERGIC-derived vesicle fusion with Golgi cis cisterna membrane|endoplasmic reticulum-Golgi intermediate compartment (ERGIC) derived vesicle fusion with cis-Golgi cisterna membrane							bhm	2015-03-12T09:41:48Z					biological_process											owl:Class	
GO:0006888	biolink:NamedThing	endoplasmic reticulum to Golgi vesicle-mediated transport	The directed movement of substances from the endoplasmic reticulum (ER) to the Golgi, mediated by COP II vesicles. Small COP II coated vesicles form from the ER and then fuse directly with the cis-Golgi. Larger structures are transported along microtubules to the cis-Golgi.	tmpzr1t_l9r_go_relaxed.owl	anterograde vesicle-mediated transport, endoplasmic reticulum to Golgi|rough endoplasmic reticulum to cis-Golgi transport|rough endoplasmic reticulum to cis-Golgi vesicle-mediated transport|endoplasmic reticulum to Golgi transport|anterograde vesicle-mediated transport, ER to Golgi|rough ER to cis-Golgi transport|rough ER to cis-Golgi vesicle-mediated transport|ER to Golgi vesicle-mediated transport|anterograde (ER to Golgi) transport|anterograde transport, ER to Golgi|anterograde transport, endoplasmic reticulum to Golgi|ER to Golgi transport											GO:0048221		biological_process											owl:Class	
GO:0005730	biolink:NamedThing	nucleolus	A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Nucleolus|NIF_Subcellular:sao1820400233									cellular_component											owl:Class	
GO:1905016	biolink:NamedThing	negative regulation of isoleucine-tRNA ligase activity	Any process that stops, prevents or reduces the frequency, rate or extent of isoleucine-tRNA ligase activity.	tmpzr1t_l9r_go_relaxed.owl	downregulation of isoleucyl-transfer RNA synthetase activity|inhibition of isoleucyl-tRNA synthetase activity|down-regulation of isoleucine-tRNA ligase activity|down regulation of isoleucine-tRNA ligase activity|down-regulation of isoleucyl-transfer RNA synthetase activity|negative regulation of L-isoleucine:tRNAIle ligase (AMP-forming)|negative regulation of isoleucine-tRNA synthetase activity|downregulation of isoleucyl-tRNA synthetase activity|down-regulation of isoleucine-transfer RNA ligase activity|inhibition of isoleucyl-transfer ribonucleate synthetase activity|down-regulation of L-isoleucine:tRNAIle ligase (AMP-forming)|negative regulation of isoleucyl-transfer ribonucleate synthetase activity|down regulation of isoleucine-transfer RNA ligase activity|negative regulation of isoleucine-transfer RNA ligase activity|negative regulation of isoleucine translase activity|down-regulation of isoleucine translase activity|inhibition of isoleucyl-transfer RNA synthetase activity|down-regulation of isoleucyl-transfer ribonucleate synthetase activity|down-regulation of isoleucyl-tRNA synthetase activity|downregulation of L-isoleucine:tRNAIle ligase (AMP-forming)|inhibition of isoleucine-transfer RNA ligase activity|inhibition of isoleucine translase activity|downregulation of isoleucyl-transfer ribonucleate synthetase activity|negative regulation of isoleucyl-tRNA synthetase activity|inhibition of L-isoleucine:tRNAIle ligase (AMP-forming)|downregulation of isoleucine translase activity|down regulation of isoleucyl-tRNA synthetase activity|down regulation of isoleucine-tRNA synthetase activity|downregulation of isoleucine-transfer RNA ligase activity|downregulation of isoleucine-tRNA ligase activity|downregulation of isoleucine-tRNA synthetase activity|down regulation of isoleucyl-transfer ribonucleate synthetase activity|down regulation of L-isoleucine:tRNAIle ligase (AMP-forming)|down-regulation of isoleucine-tRNA synthetase activity|down regulation of isoleucine translase activity|negative regulation of isoleucyl-transfer RNA synthetase activity|inhibition of isoleucine-tRNA ligase activity|inhibition of isoleucine-tRNA synthetase activity|down regulation of isoleucyl-transfer RNA synthetase activity							sl	2016-03-03T19:00:57Z					biological_process											owl:Class	
GO:0150051	biolink:NamedThing	postsynaptic Golgi apparatus	The network of the Golgi apparatus structures located within the postsynapse.	tmpzr1t_l9r_go_relaxed.owl	Golgi outpost							bc	2018-05-08T15:42:56Z					cellular_component											owl:Class	
GO:0061910	biolink:NamedThing	autophagosome-endosome fusion	The process in which an autophagosome fuses with an endosome to create an intermediate autophagic organelle called amphisome.	tmpzr1t_l9r_go_relaxed.owl								dph	2017-06-29T17:10:43Z					biological_process											owl:Class	
GO:0016236	biolink:NamedThing	macroautophagy	The major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane-bounded autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane-bounded structure.  Autophagosomes then fuse with a lysosome (or vacuole) releasing single-membrane-bounded autophagic bodies that are then degraded within the lysosome (or vacuole). Some types of macroautophagy, e.g. pexophagy, mitophagy, involve selective targeting of the targets to be degraded.	tmpzr1t_l9r_go_relaxed.owl	autophagy					Targeted macroautophagy sometimes targets regions of cytoplasm containing non-self, such as virus particles or components (e.g. see PMID:20159618).  As this is essentially the same process as macroautophagy that encloses and digests only self, the term autophagy is still used despite the enclosure of some non-self (non-auto) entities.						GO:0034262		biological_process											owl:Class	
GO:0098951	biolink:NamedThing	intrinsic component of postsynaptic recycling endosome membrane	The component of the postsynaptic recycling endosome membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.	tmpzr1t_l9r_go_relaxed.owl	intrinsic to postsynaptic recycling endosome membrane													cellular_component											owl:Class	
GO:0098944	biolink:NamedThing	postsynaptic recycling endosome membrane	The lipid bilayer surrounding a postsynaptic recycling endosome.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0014906	biolink:NamedThing	myotube cell development involved in skeletal muscle regeneration	The process aimed at the progression of a myotube cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. This occurs as part of the process of skeletal muscle regeneration. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0014908	biolink:NamedThing	myotube differentiation involved in skeletal muscle regeneration	The process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotube differentiation starts with myoblast fusion and the appearance of specific cell markers (this is the cell development step). Then individual myotubes can fuse to form bigger myotubes and start to contract. This process occurs as part of the process of skeletal muscle regeneration. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0001834	biolink:NamedThing	trophectodermal cell proliferation	The proliferation of cells in the trophectoderm.	tmpzr1t_l9r_go_relaxed.owl	trophectoderm cell proliferation					See also the Anatomical Dictionary for Mouse Development ontology terms 'TS4, trophectoderm ; EMAP:19', 'TS5, trophectoderm ; EMAP:28' and 'TS6, trophectoderm ; EMAP:39'.								biological_process											owl:Class	
GO:0020007	biolink:NamedThing	apical complex	A group of cytoskeletal structures and associated membrane-bounded organelles found at the anterior end of adult obligate intracellular protozoan parasites in the phylum Apicomplexa. The apical complex is involved in attachment to and penetration of the host cell, and in parasite proliferation.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0031910	biolink:NamedThing	cytostome	Stable, specialized structure for the ingestion of food by the cell into phagosomes.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Cytostome									cellular_component											owl:Class	
GO:0021723	biolink:NamedThing	medullary reticular formation development	The process whose specific outcome is the progression of the medullary reticular formation over time, from its formation to the mature structure. The medullary reticular formation is a series of brain nuclei located in the medulla oblongata.	tmpzr1t_l9r_go_relaxed.owl	rhombencephalic reticular formation development													biological_process											owl:Class	
GO:0019072	biolink:NamedThing	viral genome packaging	The encapsulation of the viral genome within the capsid.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0019068	biolink:NamedThing	virion assembly	A late phase of the viral life cycle during which all the components necessary for the formation of a mature virion collect at a particular site in the cell and the basic structure of the virus particle is formed.	tmpzr1t_l9r_go_relaxed.owl	viral particle assembly|bacteriophage assembly|virus assembly|phage assembly|virus particle assembly|virion assembly and maintenance|virion organization|viral assembly											GO:0042963		biological_process											owl:Class	
GO:0048259	biolink:NamedThing	regulation of receptor-mediated endocytosis	Any process that modulates the frequency, rate or extent of receptor mediated endocytosis, the uptake of external materials by cells, utilizing receptors to ensure specificity of transport.	tmpzr1t_l9r_go_relaxed.owl	regulation of receptor mediated endocytosis													biological_process											owl:Class	
GO:0035602	biolink:NamedThing	fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow cell	The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands, which stops, prevents, or reduces the frequency, rate or extent of the occurrence or rate of cell death by apoptotic process in the bone marrow.	tmpzr1t_l9r_go_relaxed.owl	fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow|fibroblast growth factor receptor signalling pathway involved in negative regulation of apoptotic process in bone marrow|FGF receptor signaling pathway involved in negative regulation of apoptosis in bone marrow|FGFR signaling pathway involved in negative regulation of apoptosis in bone marrow|fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptosis in bone marrow							bf	2010-11-15T11:09:20Z					biological_process											owl:Class	
GO:0043320	biolink:NamedThing	natural killer cell degranulation	The regulated exocytosis of secretory granules containing preformed mediators such as perforin and granzymes by a natural killer cell.	tmpzr1t_l9r_go_relaxed.owl	natural killer cell granule exocytosis|NK cell granule exocytosis|NK cell degranulation													biological_process											owl:Class	
GO:0042267	biolink:NamedThing	natural killer cell mediated cytotoxicity	The directed killing of a target cell by a natural killer cell through the release of granules containing cytotoxic mediators or through the engagement of death receptors.	tmpzr1t_l9r_go_relaxed.owl	natural killer cell mediated cytolysis|NK cell mediated cytolysis|natural killer cell mediated cell killing|killer activity|NK cell mediated cell killing|NK cell mediated cell death|natural killer-cell mediated cytolysis|NK cell mediated cytotoxicity|natural killer cell mediated cell death					Note that either or both mechanisms mentioned in the definition may be used in this process. Note that both granule release and the engagement of death receptors on target cells result in induction of apoptosis in the target cell.								biological_process											owl:Class	
GO:0071006	biolink:NamedThing	U2-type catalytic step 1 spliceosome	A spliceosomal complex that is formed by the displacement of the U1 and U4 snRNPs from the precatalytic spliceosome; the U2, U5 and U6 snRNPs remain associated with the mRNA. This complex, sometimes called the activated spliceosome, is the catalytically active form of the spliceosome, and includes many proteins in addition to those found in the U2, and U5 and U6 snRNPs.	tmpzr1t_l9r_go_relaxed.owl	mammalian U2-type spliceosomal complex B2|mammalian U2-type spliceosomal complex B*|GT-AG catalytic step 1 spliceosome|yeast U2-type spliceosomal complex A1|major catalytic step 1 spliceosome|U2-type activated spliceosome							mah	2009-07-30T12:00:35Z					cellular_component											owl:Class	
GO:0004691	biolink:NamedThing	cAMP-dependent protein kinase activity	cAMP-dependent catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein.	tmpzr1t_l9r_go_relaxed.owl	cyclic AMP-dependent protein kinase activity|adenosine 3',5'-cyclophosphate-dependent protein kinase activity|ATP:protein phosphotransferase (cAMP-dependent) activity|PKA C|3',5' cAMP-dependent protein kinase activity|3',5'-cAMP-dependent protein kinase activity|STK22|PKA|protein kinase A activity|AMPK|cAMP-dependent protein kinase, intrinsic catalyst activity				Reactome:R-HSA-913451|Reactome:R-HSA-163672|Reactome:R-HSA-5617182|Reactome:R-HSA-5687088|Reactome:R-HSA-5610720|Reactome:R-HSA-5610717|Reactome:R-HSA-432232|Reactome:R-HSA-177275|Reactome:R-HSA-177284|Reactome:R-HSA-5610741|Reactome:R-HSA-5617179|EC:2.7.11.11|Reactome:R-HSA-163773|Reactome:R-HSA-163676|MetaCyc:2.7.11.11-RXN	This reaction requires the presence of cAMP.						GO:0008602		molecular_function											owl:Class	
GO:0002404	biolink:NamedThing	antigen sampling in mucosal-associated lymphoid tissue	The process of apical-to-basolateral delivery of soluble and particulate antigens to underlying mucosal-associated lymphoid tissue.	tmpzr1t_l9r_go_relaxed.owl	antigen transport in mucosal-associated lymphoid tissue|antigen transport in MALT|antigen sampling in MALT													biological_process											owl:Class	
GO:0002385	biolink:NamedThing	mucosal immune response	An immune response taking place in mucosal tissues, including those of the intestinal tract, nasal and upper respiratory tract, and genital tract.	tmpzr1t_l9r_go_relaxed.owl	immune response in urogenital tract|immune response in MALT|immune response in mucosal-associated lymphoid tissue											GO:0002422|GO:0002386		biological_process											owl:Class	
GO:0015343	biolink:NamedThing	siderophore transmembrane transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: siderophore-iron(out) + H+(out) = siderophore-iron(in) + H+(in).	tmpzr1t_l9r_go_relaxed.owl	siderophore-iron transmembrane transporter activity|siderochrome-iron transporter activity|siderophore transporter activity|iron-siderophore transporter activity|siderophore-iron transporter activity|siderochrome transporter activity				Reactome:R-HSA-1222597							GO:0042927|GO:0015237|GO:0015236		molecular_function											owl:Class	
GO:0044718	biolink:NamedThing	siderophore transmembrane transport	The directed movement of siderophores, low molecular weight Fe(III)-chelating substances, from one side of a membrane to the other, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	siderophore membrane transport					Note that this term is not intended for use in annotating lateral movement within membranes.		jl	2012-10-18T13:43:56Z					biological_process											owl:Class	
GO:0044386	biolink:NamedThing	integral to host endoplasmic reticulum membrane	Penetrating at least one phospholipid bilayer of an endoplasmic reticulum membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer. Occurring in a host cell.	tmpzr1t_l9r_go_relaxed.owl								jl	2011-12-13T04:11:30Z					cellular_component											owl:Class	
GO:0044167	biolink:NamedThing	host cell endoplasmic reticulum membrane	The lipid bilayer surrounding the host cell endoplasmic reticulum.	tmpzr1t_l9r_go_relaxed.owl	host endoplasmic reticulum membrane							jl	2009-09-04T11:19:23Z					cellular_component											owl:Class	
GO:0005231	biolink:NamedThing	excitatory extracellular ligand-gated ion channel activity	Enables the transmembrane transfer of an ion by a channel that opens when a specific extracellular ligand has been bound by the channel complex or one of its constituent parts, where channel opening contributes to an increase in membrane potential.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-420980|Reactome:R-HSA-399712|Reactome:R-HSA-432164|Reactome:R-HSA-399711|Reactome:R-HSA-438037									molecular_function											owl:Class	
GO:0038029	biolink:NamedThing	epidermal growth factor receptor signaling pathway via MAPK cascade	The series of molecular signals generated as a consequence of an epidermal growth factor receptor binding to one of its physiological ligands, where the signal is passed on via the MAPKKK cascade.	tmpzr1t_l9r_go_relaxed.owl	EGFR/MAPK signaling|EGFR signaling pathway via MAPKKK cascade|epidermal growth factor receptor signalling pathway via MAPKKK cascade|EGFR signaling via MAPKKK cascade|epidermal growth factor receptor signaling pathway via MAPKKK cascade							bf	2011-09-08T10:53:01Z					biological_process											owl:Class	
GO:0086061	biolink:NamedThing	voltage-gated sodium channel activity involved in bundle of His cell action potential	Enables the transmembrane transfer of a sodium ion by a voltage-gated channel through the plasma membrane of a bundle of His cardiac muscle cell contributing to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.	tmpzr1t_l9r_go_relaxed.owl	voltage-gated sodium channel activity involved in bundle of His cardiac muscle cell action potential							dph	2011-11-17T12:58:13Z					molecular_function											owl:Class	
GO:0060892	biolink:NamedThing	limb basal epidermal cell fate specification	The process in which a cell becomes capable of differentiating autonomously into an limb basal epidermal cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-08-13T01:41:47Z					biological_process											owl:Class	
GO:0071828	biolink:NamedThing	apolipoprotein E recycling	The process in which chylomicron remnant-associated apolipoprotein E is internalized by endocytosis, localized to recycling endosomes and then secreted in association with a high-density lipoprotein particle.	tmpzr1t_l9r_go_relaxed.owl	APOE recycling							mah	2010-09-08T11:05:15Z					biological_process											owl:Class	
GO:0034382	biolink:NamedThing	chylomicron remnant clearance	The process in which a chylomicron remnant is removed from the blood via receptor-mediated endocytosis into liver cells and its constituent parts degraded.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0002269	biolink:NamedThing	leukocyte activation involved in inflammatory response	A change in the morphology or behavior of a leukocyte resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an inflammatory response.	tmpzr1t_l9r_go_relaxed.owl	immune cell activation during inflammatory response|leukocyte activation during inflammatory response													biological_process											owl:Class	
GO:0043002	biolink:NamedThing	negative regulation of Golgi to plasma membrane CFTR protein transport	Any process that stops, prevents, or reduces the frequency, rate or extent of transport of Cystic Fibrosis Transmembrane conductance Regulator (CFTR) protein from the Golgi to the plasma membrane.	tmpzr1t_l9r_go_relaxed.owl	downregulation of Golgi to plasma membrane CFTR protein transport|inhibition of Golgi to plasma membrane CFTR protein transport|down regulation of Golgi to plasma membrane CFTR protein transport|down-regulation of Golgi to plasma membrane CFTR protein transport													biological_process											owl:Class	
GO:0043000	biolink:NamedThing	Golgi to plasma membrane CFTR protein transport	The directed movement of Cystic Fibrosis Transmembrane conductance Regulator (CFTR) protein from the Golgi to the plasma membrane.	tmpzr1t_l9r_go_relaxed.owl	Golgi to plasma membrane cystic fibrosis transmembrane conductance regulator protein transport													biological_process											owl:Class	
GO:0001880	biolink:NamedThing	Mullerian duct regression	The process in which the Mullerian ducts, primordia of the oviducts, uterus and upper vagina, undergo regression in male embryos.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0046661	biolink:NamedThing	male sex differentiation	The establishment of the sex of a male organism by physical differentiation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0022006	biolink:NamedThing	zona limitans intrathalamica formation	The formation of the narrow stripe of cells that lies between the prospective dorsal and ventral thalami. This boundary contains signals that pattern the prethalamic and thalamic territories of the future mid-diencephalon.	tmpzr1t_l9r_go_relaxed.owl	zli biosynthesis|zli formation													biological_process											owl:Class	
GO:0021903	biolink:NamedThing	rostrocaudal neural tube patterning	The process in which the neural tube is divided into specific regions along the rostrocaudal axis.	tmpzr1t_l9r_go_relaxed.owl	anterior-posterior neural tube patterning													biological_process											owl:Class	
GO:0051490	biolink:NamedThing	negative regulation of filopodium assembly	Any process that stops, prevents, or reduces the frequency, rate or extent of the assembly of a filopodium, a thin, stiff protrusion extended by the leading edge of a motile cell such as a crawling fibroblast or amoeba, or an axonal growth cone.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of filopodia biosynthesis|inhibition of filopodium formation|down regulation of filopodium formation|down-regulation of filopodium formation|negative regulation of filopodium formation|negative regulation of filopodia formation|downregulation of filopodium formation													biological_process											owl:Class	
GO:0035474	biolink:NamedThing	selective angioblast sprouting	The segregation of angioblasts into discrete arterial and venous vessels from one common precursor vessel.	tmpzr1t_l9r_go_relaxed.owl								bf	2010-04-23T10:03:55Z					biological_process											owl:Class	
GO:1904134	biolink:NamedThing	negative regulation of convergent extension involved in rhombomere morphogenesis	Any process that stops, prevents or reduces the frequency, rate or extent of convergent extension involved in rhombomere morphogenesis.	tmpzr1t_l9r_go_relaxed.owl	inhibition of convergent extension involved in rhombomere morphogenesis|down regulation of convergent extension involved in rhombomere morphogenesis|down-regulation of convergent extension involved in rhombomere morphogenesis|downregulation of convergent extension involved in rhombomere morphogenesis							dph	2015-04-10T21:21:18Z					biological_process											owl:Class	
GO:1904125	biolink:NamedThing	convergent extension involved in rhombomere morphogenesis	Any convergent extension that is involved in rhombomere morphogenesis.	tmpzr1t_l9r_go_relaxed.owl								dph	2015-04-10T21:12:50Z					biological_process											owl:Class	
GO:2001100	biolink:NamedThing	pentasaccharide transport	The directed movement of a pentasaccharideacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl								jl	2011-09-21T02:17:07Z					biological_process											owl:Class	
GO:1900361	biolink:NamedThing	negative regulation of pentasaccharide transport	Any process that stops, prevents or reduces the frequency, rate or extent of pentasaccharide transport.	tmpzr1t_l9r_go_relaxed.owl	down regulation of pentasaccharide transport|inhibition of pentasaccharide transport|down-regulation of pentasaccharide transport|downregulation of pentasaccharide transport							tt	2012-04-06T02:19:36Z					biological_process											owl:Class	
GO:0002420	biolink:NamedThing	natural killer cell mediated cytotoxicity directed against tumor cell target	The directed killing of a tumor cell by a natural killer cell through the release of granules containing cytotoxic mediators or through the engagement of death receptors.	tmpzr1t_l9r_go_relaxed.owl	NK cell mediated cytotoxicity directed against tumor cell target					Note that either or both mechanisms mentioned in the definition may be used in this process. Note that both granule release and the engagement of death receptors on target cells result in induction of apoptosis in the target cell.								biological_process											owl:Class	
GO:0035762	biolink:NamedThing	dorsal motor nucleus of vagus nerve morphogenesis	The process in which the dorsal motor nucleus of the vagus nerve is generated and organized. Morphogenesis pertains to the creation of form.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-03-29T02:47:18Z					biological_process											owl:Class	
GO:1902379	biolink:NamedThing	chemoattractant activity involved in axon guidance	Any chemoattractant activity that is involved in axon guidance.	tmpzr1t_l9r_go_relaxed.owl	chemoattractant activity involved in axon growth cone guidance|chemoattractant activity involved in axon pathfinding|chemoattractant activity involved in axon chemotaxis							bf	2013-09-02T13:49:35Z					molecular_function											owl:Class	
GO:0021575	biolink:NamedThing	hindbrain morphogenesis	The process in which the anatomical structure of the hindbrain is generated and organized. The hindbrain is the region consisting of the medulla, pons and cerebellum. Areas of the hindbrain control motor and autonomic functions.	tmpzr1t_l9r_go_relaxed.owl	rhombencephalon morphogenesis													biological_process											owl:Class	
GO:0030917	biolink:NamedThing	midbrain-hindbrain boundary development	The process whose specific outcome is the progression of the midbrain-hindbrain boundary over time, from its formation to the mature structure. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages.	tmpzr1t_l9r_go_relaxed.owl	isthmic organizer development|isthmomesencephalic boundary development|MHB development|midbrain-hindbrain orgainizer development|isthmus development													biological_process											owl:Class	
GO:1901310	biolink:NamedThing	positive regulation of sterol regulatory element binding protein cleavage	Any process that activates or increases the frequency, rate or extent of sterol regulatory element binding protein cleavage.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of sterol regulatory element binding protein cleavage|upregulation of SREBP cleavage|upregulation of sterol regulatory element binding protein cleavage|positive regulation of SREBP cleavage|activation of sterol regulatory element binding protein cleavage|up regulation of sterol regulatory element binding protein cleavage|up-regulation of SREBP cleavage|up regulation of SREBP cleavage|activation of SREBP cleavage							bf	2012-08-21T16:43:40Z					biological_process											owl:Class	
GO:0035103	biolink:NamedThing	sterol regulatory element binding protein cleavage	The proteolytic release of a transcriptionally active sterol regulatory element binding protein (SREBP) from intracellular membranes, freeing it to move to the nucleus to upregulate transcription of target genes, in response to altered levels of one or more lipids.	tmpzr1t_l9r_go_relaxed.owl	sterol regulatory element binding protein cleavage involved in ER-nuclear sterol response pathway|sterol depletion response, SREBP cleavage|SREBP cleavage											GO:0006992		biological_process											owl:Class	
GO:1904135	biolink:NamedThing	positive regulation of convergent extension involved in rhombomere morphogenesis	Any process that activates or increases the frequency, rate or extent of convergent extension involved in rhombomere morphogenesis.	tmpzr1t_l9r_go_relaxed.owl	upregulation of convergent extension involved in rhombomere morphogenesis|up regulation of convergent extension involved in rhombomere morphogenesis|activation of convergent extension involved in rhombomere morphogenesis|up-regulation of convergent extension involved in rhombomere morphogenesis							dph	2015-04-10T21:21:24Z					biological_process											owl:Class	
GO:0000139	biolink:NamedThing	Golgi membrane	The lipid bilayer surrounding any of the compartments of the Golgi apparatus.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:1903519	biolink:NamedThing	regulation of mammary gland involution	Any process that modulates the frequency, rate or extent of mammary gland involution.	tmpzr1t_l9r_go_relaxed.owl								dph	2014-10-06T12:01:22Z					biological_process											owl:Class	
GO:0010673	biolink:NamedThing	positive regulation of transcription from RNA polymerase II promoter involved in meiotic cell cycle	Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as part of the meiotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of meiosis by positive regulation of transcription from RNA polymerase II promoter|up-regulation of meiosis by positive regulation of transcription from RNA polymerase II promoter|activation of meiosis by positive regulation of transcription from RNA polymerase II promoter|stimulation of meiosis by positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter, meiotic|upregulation of meiosis by positive regulation of transcription from RNA polymerase II promoter|up regulation of meiosis by positive regulation of transcription from RNA polymerase II promoter							dgf	2012-05-01T08:40:11Z			GO:1900476		biological_process											owl:Class	
GO:2000853	biolink:NamedThing	negative regulation of corticosterone secretion	Any process that stops, prevents or reduces the frequency, rate or extent of corticosterone secretion.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-07-26T08:45:43Z					biological_process											owl:Class	
GO:0010377	biolink:NamedThing	guard cell fate commitment	The process in which the developmental fate of a cell becomes restricted such that it will develop into a stomatal guard cell. Guard cells are located in the leaf epidermis and pairwise surround stomatal pores, which allow CO2 influx for photosynthetic carbon fixation and water loss via transpiration to the atmosphere.	tmpzr1t_l9r_go_relaxed.owl	stomatal cell fate commitment													biological_process											owl:Class	
GO:0010052	biolink:NamedThing	guard cell differentiation	The process in which a guard mother cell acquires the specialized features of a guard cell.	tmpzr1t_l9r_go_relaxed.owl	stomatal cell differentiation													biological_process											owl:Class	
GO:2000777	biolink:NamedThing	positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia	Any positive regulation of proteasomal ubiquitin-dependent protein catabolic process that is involved in a cellular response to hypoxia.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to lowered oxygen tension|positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxic stress							mah	2011-06-22T04:07:20Z					biological_process											owl:Class	
GO:0071456	biolink:NamedThing	cellular response to hypoxia	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level.	tmpzr1t_l9r_go_relaxed.owl	cellular response to hypoxic stress|cellular response to lowered oxygen tension					Note that this term should not be confused with 'cellular response to anoxia ; GO:0071454'. Note that in laboratory studies, hypoxia is typically studied at O2 concentrations ranging from 0.1 - 5%.		mah	2009-12-16T04:45:20Z					biological_process											owl:Class	
GO:0052884	biolink:NamedThing	all-trans-retinyl-palmitate hydrolase, 11-cis retinol forming activity	Catalysis of the reaction: H(2)O + all-trans-retinyl palmitate = 11-cis-retinol + H(+) + palmitate.	tmpzr1t_l9r_go_relaxed.owl	retinol isomerase activity|retinoid isomerohydrolase activity|all-trans-retinol isomerase:hydrolase activity|all-trans-retinyl-palmitate hydrolase activity				RHEA:31775|EC:3.1.1.64|Reactome:R-HSA-2453833									molecular_function											owl:Class	
GO:0003796	biolink:NamedThing	lysozyme activity	Catalysis of the hydrolysis of the beta-(1->4) linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan.	tmpzr1t_l9r_go_relaxed.owl	peptidoglycan N-acetylmuramoylhydrolase activity|globulin G1|mucopeptide N-acetylmuramoylhydrolase activity|mucopeptide glucohydrolase activity|L-7001|globulin G|PR1-lysozyme|lysozyme g|muramidase activity|1,4-N-acetylmuramidase activity|N,O-diacetylmuramidase activity				MetaCyc:3.2.1.17-RXN|Reactome:R-HSA-8862320|EC:3.2.1.17									molecular_function											owl:Class	
GO:0009048	biolink:NamedThing	dosage compensation by inactivation of X chromosome	Compensating for the two-fold variation in X-chromosome:autosome ratios between sexes by a global inactivation of all, or most of, the genes on one of the X-chromosomes in the XX sex.	tmpzr1t_l9r_go_relaxed.owl	Barr body formation|chromosome inactivation|X chromosome inactivation				Wikipedia:X-inactivation									biological_process											owl:Class	
GO:0043611	biolink:NamedThing	isoprene metabolic process	The chemical reactions and pathways involving isoprene, C5H8.	tmpzr1t_l9r_go_relaxed.owl	hemiterpene metabolism|hemiterpene metabolic process|2-methyl-1,3-butadiene metabolic process|isoprene metabolism|2-methyl-1,3-butadiene metabolism													biological_process											owl:Class	
GO:0017056	biolink:NamedThing	structural constituent of nuclear pore	The action of a molecule that contributes to the structural integrity of the nuclear pore complex, a protein-lined channel in the nuclear envelope that allows the transfer of macromolecules.	tmpzr1t_l9r_go_relaxed.owl	nucleocytoplasmic transporter activity|nuclear pore activity				Reactome:R-HSA-192925|Reactome:R-HSA-5252041|Reactome:R-HSA-1176059|Reactome:R-HSA-5661474|Reactome:R-HSA-5578744|Reactome:R-HSA-192627|Reactome:R-HSA-6783483|Reactome:R-HSA-170796	Note that this term is meant to be used for nuclear pore proteins. For importins and exportins, consider 'nuclear import signal receptor activity' or 'nuclear export signal receptor activity', respectively.		tb	2015-06-29T08:59:16Z			GO:0005487		molecular_function											owl:Class	
GO:0005643	biolink:NamedThing	nuclear pore	A protein complex providing a discrete opening in the nuclear envelope of a eukaryotic cell, where the inner and outer nuclear membranes are joined.	tmpzr1t_l9r_go_relaxed.owl	nucleopore|NPC|nuclear pore membrane protein|nuclear pore complex				Wikipedia:Nuclear_pore|NIF_Subcellular:sao220861693							GO:0005644		cellular_component											owl:Class	
GO:0060104	biolink:NamedThing	surface coat of collagen and cuticulin-based cuticle extracellular matrix	An electron dense, amorphous envelope that comprises the outermost layer of the cuticle. The surface coat is loosely apposed to the epicuticle, has distinct biochemical properties, is synthesized by cells other than the underlying hypodermis, and is labile. In addition to serving as a lubricant to protect against abrasion and dehydration, the surface coat may also play important roles in infection and immune evasion. An example of this component is found in Caenorhabditis elegans.	tmpzr1t_l9r_go_relaxed.owl	surface coat of collagen and cuticulin-based exoskeleton extracellular matrix													cellular_component											owl:Class	
GO:0000779	biolink:NamedThing	condensed chromosome, centromeric region	The region of a condensed chromosome that includes the centromere and associated proteins, including the kinetochore. In monocentric chromosomes, this region corresponds to a single area of the chromosome, whereas in holocentric chromosomes, it is evenly distributed along the chromosome.	tmpzr1t_l9r_go_relaxed.owl	condensed chromosome, centromere|condensed chromosome, centric region|condensed chromosome, pericentric region|condensed nuclear chromosome, centromeric region					Note that this term can be used in place of the obsolete cellular component term 'centromere ; GO:0005698'. Use with caution because this term refers to a specific region of the chromosome and not a protein complex.						GO:0000780		cellular_component											owl:Class	
GO:0000793	biolink:NamedThing	condensed chromosome	A highly compacted molecule of DNA and associated proteins resulting in a cytologically distinct structure.	tmpzr1t_l9r_go_relaxed.owl	cytoplasmic mitotic chromosome|metaphase chromosome|mitotic chromosome					Note that this term can be used to annotate gene products that localize to a mitotic chromosome in an organism that undergoes an 'open mitosis' in which the nuclear envelope breaks down during mitosis.								cellular_component											owl:Class	
GO:0009543	biolink:NamedThing	chloroplast thylakoid lumen	The cavity enclosed within the chloroplast thylakoid membrane. An example of this component is found in Arabidopsis thaliana.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0009534	biolink:NamedThing	chloroplast thylakoid	Sac-like membranous structures (cisternae) in a chloroplast combined into stacks (grana) and present singly in the stroma (stroma thylakoids or frets) as interconnections between grana. An example of this component is found in Arabidopsis thaliana.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0015385	biolink:NamedThing	sodium:proton antiporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Na+(out) + H+(in) = Na+(in) + H+(out).	tmpzr1t_l9r_go_relaxed.owl	pH-dependent sodium:hydrogen antiporter activity|sodium/hydrogen antiporter activity|pH-dependent sodium:proton antiporter activity|sodium:hydrogen exchange activity|sodium:hydrogen exchanger|sodium:hydrogen antiporter activity				RHEA:29251|Reactome:R-HSA-5661039|Reactome:R-HSA-426015|Reactome:R-HSA-2872444|Reactome:R-HSA-425965|Reactome:R-HSA-5661086|Reactome:R-HSA-2872463|Reactome:R-HSA-425983|Reactome:R-HSA-425994							GO:0015502		molecular_function											owl:Class	
GO:0036444	biolink:NamedThing	calcium import into the mitochondrion	A process in which a calcium ion (Ca2+) is transported from the cytosol into the mitochondrial matrix.	tmpzr1t_l9r_go_relaxed.owl	calcium ion transmembrane import into mitochondrion|mitochondrial calcium uptake|mitochondrial calcium ion import|calcium ion import into mitochondrion							bf	2013-10-28T09:32:39Z					biological_process											owl:Class	
GO:0022024	biolink:NamedThing	BMP signaling pathway involved in forebrain neuron fate commitment	A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, which contributes to the commitment of a neuroblast to a neuronal fate. The neuron will reside in the forebrain.	tmpzr1t_l9r_go_relaxed.owl	bone morphogenetic protein signaling pathway involved in forebrain neuron fate commitment|bone morphogenetic protein signalling pathway involved in forebrain neuron fate commitment|BMP signalling pathway involved in forebrain neuron fate commitment													biological_process											owl:Class	
GO:1900505	biolink:NamedThing	positive regulation of cellulosome assembly	Any process that activates or increases the frequency, rate or extent of cellulosome assembly.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of cellulosome assembly|upregulation of cellulosome assembly|up regulation of cellulosome assembly|activation of cellulosome assembly							tt	2012-05-02T03:58:35Z					biological_process											owl:Class	
GO:0044575	biolink:NamedThing	cellulosome assembly	The assembly of a cellulosome, a macromolecular multi-enzyme complex in bacteria that facilitates the breakdown of cellulase, hemicellulase and pectin in the plant cell wall.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-04-19T03:42:36Z					biological_process											owl:Class	
GO:0044770	biolink:NamedThing	cell cycle phase transition	The cell cycle process by which a cell commits to entering the next cell cycle phase.	tmpzr1t_l9r_go_relaxed.owl	cell cycle transition							jl	2013-02-28T12:54:59Z					biological_process											owl:Class	
GO:0016791	biolink:NamedThing	phosphatase activity	Catalysis of the hydrolysis of phosphoric monoesters, releasing inorganic phosphate.	tmpzr1t_l9r_go_relaxed.owl	phosphatase|phosphoric monoester hydrolase activity|K-pNPPase activity|ecto-p-nitrophenyl phosphatase activity|4-nitrophenylphosphatase activity|nitrophenyl phosphatase activity|4-nitrophenylphosphate phosphohydrolase activity|p-nitrophenylphosphatase activity|p-nitrophenylphosphate phosphohydrolase activity|PNPPase activity|NPPase activity|para-nitrophenyl phosphatase activity				EC:3.1.3.-|Reactome:R-HSA-9636457|Reactome:R-HSA-4419986|MetaCyc:4-NITROPHENYLPHOSPHATASE-RXN							GO:0016302|GO:0003869		molecular_function											owl:Class	
GO:0030042	biolink:NamedThing	actin filament depolymerization	Disassembly of actin filaments by the removal of actin monomers from a filament.	tmpzr1t_l9r_go_relaxed.owl	actin depolymerization|actin depolymerizing activity													biological_process											owl:Class	
GO:0003384	biolink:NamedThing	apical constriction involved in gastrulation	The actin-mediated process that results in the contraction of the apical end of a polarized columnar epithelial cell, contributing to the process of gastrulation.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-12-09T07:35:38Z					biological_process											owl:Class	
GO:0007369	biolink:NamedThing	gastrulation	A complex and coordinated series of cellular movements that occurs at the end of cleavage during embryonic development of most animals. The details of gastrulation vary from species to species, but usually result in the formation of the three primary germ layers, ectoderm, mesoderm and endoderm.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Gastrulation									biological_process											owl:Class	
GO:0006907	biolink:NamedThing	pinocytosis	An endocytosis process that results in the uptake of liquid material by cells from their external environment; literally 'cell drinking'. Liquid is enclosed in vesicles, called pinosomes, formed by invagination of the plasma membrane.	tmpzr1t_l9r_go_relaxed.owl	single-organism pinocytosis|fluid-phase endocytosis|clathrin-independent pinocytosis				Wikipedia:Pinocytosis			jl	2013-12-02T14:14:38Z			GO:0006908|GO:1902536		biological_process											owl:Class	
GO:0060529	biolink:NamedThing	squamous basal epithelial stem cell differentiation involved in prostate gland acinus development	The process in which a relatively unspecialized epithelial cell acquires specialized features of a squamous basal epithelial stem cell of the prostate.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0060525	biolink:NamedThing	prostate glandular acinus development	The progression of a glandular acinus of the prostate gland over time, from its initial formation to the mature structure. The glandular acini are the saclike structures of the gland.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0021584	biolink:NamedThing	pons formation	The process that gives rise to the pons. This process pertains to the initial formation of a structure from unspecified parts. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0021583	biolink:NamedThing	pons morphogenesis	The process in which the anatomical structure of the pons is generated and organized. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0021872	biolink:NamedThing	forebrain generation of neurons	The process in which nerve cells are generated in the forebrain. This includes the production of neuroblasts from and their differentiation into neurons.	tmpzr1t_l9r_go_relaxed.owl	generation of neurons in forebrain													biological_process											owl:Class	
GO:0140537	biolink:NamedThing	transcription regulator activator activity	A molecular function regulator that increases the activity of a transcription regulator via direct binding and/or post-translational modification.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/16132				Usage guidance: transcription regulator activators bind to a transcription regulator to allow it to reach the chromatin or to contact other transcriptional regulators. This activity does not occur at the promoter. For activities that do occur at the promoter, consider GO:0001216 ; DNA-binding transcription activator activity or GO:0003713; transcription coactivator activity; those activities respectively bind DNA themselves or positively regulate a transcription regulator when it is located at the chromatin.		pg	2020-11-03T14:04:59Z					molecular_function											owl:Class	
GO:0140395	biolink:NamedThing	averantin hydroxylase activity	Catalyzes the reaction: (1'S)-averantin + [reduced NADPH--hemoprotein reductase] + O(2) <=> (1'S,5'S)-5'-hydroxyaverantin + [oxidized NADPH--hemoprotein reductase] + H(2)O. Involved in aflatoxin biosynthesis.	tmpzr1t_l9r_go_relaxed.owl					RHEA:35575|MetaCyc:RXN-9482|EC:1.14.14.116			pg	2019-11-29T08:48:23Z					molecular_function											owl:Class	
GO:0072273	biolink:NamedThing	metanephric nephron morphogenesis	The process in which the anatomical structures of the metanephric nephron are generated and organized. A metanephric nephron is the functional unit of the metanephros.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-03-30T03:33:19Z					biological_process											owl:Class	
GO:0150140	biolink:NamedThing	regulation of CD86 production	Any process that modulates the frequency, rate or extent of CD86 biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of CD86 biosynthetic process							bc	2019-12-08T09:31:00Z					biological_process											owl:Class	
GO:0035781	biolink:NamedThing	CD86 biosynthetic process	The chemical reactions and pathways resulting in the formation of CD86, a CD marker that occurs on antigen presenting cells that provides co-stimulatory signals necessary for T cell activation and survival.	tmpzr1t_l9r_go_relaxed.owl	CD86 anabolism|CD86 biosynthesis|CD86 formation|CD86 synthesis							bf	2011-04-04T11:20:40Z					biological_process											owl:Class	
GO:1905856	biolink:NamedThing	negative regulation of pentose-phosphate shunt	Any process that stops, prevents or reduces the frequency, rate or extent of pentose-phosphate shunt.	tmpzr1t_l9r_go_relaxed.owl								vw	2017-01-23T14:00:18Z					biological_process											owl:Class	
GO:0006098	biolink:NamedThing	pentose-phosphate shunt	The metabolic process in which glucose-6-phosphate is oxidized to form carbon dioxide (CO2) and ribulose 5-phosphate, coupled to reduction of NADP+ to NADPH; ribulose 5-P then enters a series of reactions that can yield biosynthetic precursors (ribose-5-phosphate and erythrose-4-phosphate) and glycolytic intermediates (fructose-6-phosphate and glyceraldehyde-3-phosphate).	tmpzr1t_l9r_go_relaxed.owl	pentose phosphate shunt|pentose phosphate pathway|hexose monophosphate pathway|pentose-phosphate pathway				Wikipedia:Pentose_phosphate_pathway|Reactome:R-HSA-71336|KEGG_PATHWAY:00030|MetaCyc:PENTOSE-P-PWY									biological_process											owl:Class	
GO:0072766	biolink:NamedThing	centromere clustering at the mitotic interphase nuclear envelope	The process in which chromatin, or kinetochores are anchored to the nuclear envelope. This process involves the microtubule cytoskeleton, and nuclear tethering factors and is responsible for the Rabl-like configuration of chromosomes in the interphase nuclei.	tmpzr1t_l9r_go_relaxed.owl	centromere-SPB clustering|kinetochore clustering at the old mitotic spindle pole body|kinetochore clustering at spindle pole body|centromere clustering at the nuclear periphery|centromere clustering at the mitotic nuclear envelope|rabl configuration|kinetochore localization at spindle pole body|kinetochore clustering at SPB	https://github.com/geneontology/go-ontology/issues/19227|https://github.com/geneontology/go-ontology/issues/20122						mah	2012-11-21T13:32:22Z					biological_process											owl:Class	
GO:0070591	biolink:NamedThing	ascospore wall biogenesis	A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of an ascospore wall.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-04-28T01:12:11Z					biological_process											owl:Class	
GO:0030437	biolink:NamedThing	ascospore formation	The process in which cells that are products of meiosis acquire the specialized features of ascospores. Ascospores are generally found in clusters of four or eight spores within a single mother cell, the ascus, and are characteristic of the ascomycete fungi (phylum Ascomycota).	tmpzr1t_l9r_go_relaxed.owl	spore formation|sporulation|ascospore biosynthesis					Note that ascospores and asci are separate biological structures. The ascus is the structure that contain the ascospores, but the development of the ascus is a different process than the formation of the ascospores themselves; for instance, some mutations affect sporulation without affecting ascus development. For this reason, GO:0030437 ascospore formation and GO:0075317 ascus development are different terms and are not linked.						GO:0007151		biological_process											owl:Class	
GO:2000090	biolink:NamedThing	regulation of mesonephric glomerular mesangial cell proliferation	Any process that modulates the frequency, rate or extent of mesonephric glomerular mesangial cell proliferation.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-09-03T06:10:28Z					biological_process											owl:Class	
GO:0120272	biolink:NamedThing	positive regulation of nuclear-transcribed mRNA catabolic process, meiosis-specific transcripts	Any process that activates or increases the frequency, rate or extent of degradation of meiosis-specific nuclear transcribed transcripts during vegetative growth, by a mechanism that requires determinant of selective removal (DSR) sequences in the targeted mRNAs and involves a YTH family protein.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/18757						krc	2020-10-08T21:09:03Z					biological_process											owl:Class	
GO:0033621	biolink:NamedThing	nuclear-transcribed mRNA catabolic process, meiosis-specific transcripts	The chemical reactions and pathways resulting in the selective degradation of meiosis-specific transcripts during vegetative growth, by a mechanism that requires determinant of selective removal (DSR) sequences in the targeted mRNAs and involves a YTH family protein.	tmpzr1t_l9r_go_relaxed.owl	degradation of meiosis-specific transcripts|mRNA breakdown, meiosis-specific transcripts|nuclear mRNA catabolic process, meiosis-specific transcripts|mRNA catabolism, meiosis-specific transcripts|mRNA degradation, meiosis-specific transcripts					Note that it is speculated that higher eukaryotic YTH-family protein may be involved in similar mechanisms to supress gene regulation during gametogenesis or general silencing.								biological_process											owl:Class	
GO:0086063	biolink:NamedThing	voltage-gated sodium channel activity involved in SA node cell action potential	Enables the transmembrane transfer of a sodium ion by a voltage-gated channel through the plasma membrane of an SA node cardiac muscle cell contributing to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.	tmpzr1t_l9r_go_relaxed.owl	voltage-gated sodium channel activity involved in SAN cardiac muscle cell action potential|voltage-gated sodium channel activity involved in sinus node cardiac muscle cell action potential|voltage-gated sodium channel activity involved in sinoatrial node cardiac muscle cell action potential|voltage-gated sodium channel activity involved in SA node cardiac muscle cell action potential							dph	2011-11-17T01:53:08Z					molecular_function											owl:Class	
GO:0009960	biolink:NamedThing	endosperm development	The process whose specific outcome is the progression of the endosperm over time, from its formation to the mature structure. The endosperm is formed during fertilization and provides nutrients to the developing embryo.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1902281	biolink:NamedThing	negative regulation of RNA helicase activity	Any process that stops, prevents or reduces the frequency, rate or extent of ATP-dependent RNA helicase activity.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of ATP-dependent RNA helicase activity|down regulation of ATP-dependent RNA helicase activity|negative regulation of ATP-dependent RNA helicase activity|inhibition of ATP-dependent RNA helicase activity|downregulation of ATP-dependent RNA helicase activity							rb	2013-07-03T18:05:25Z					biological_process											owl:Class	
GO:2001161	biolink:NamedThing	negative regulation of histone H3-K79 methylation	Any process that stops, prevents or reduces the frequency, rate or extent of histone H3-K79 methylation.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of histone lysine H3 K79 methylation|negative regulation of histone H3 K79 methylation|negative regulation of histone H3K79me							se	2011-10-25T10:27:05Z					biological_process											owl:Class	
GO:0034729	biolink:NamedThing	histone H3-K79 methylation	The modification of histone H3 by addition of a methyl group to lysine at position 79 of the histone.	tmpzr1t_l9r_go_relaxed.owl	histone H3K79me|histone H3 K79 methylation|histone lysine H3 K79 methylation													biological_process											owl:Class	
GO:1903754	biolink:NamedThing	cortical microtubule plus-end	The plus-end of a cortical microtubule.	tmpzr1t_l9r_go_relaxed.owl	cortical microtubule plus end							jl	2014-12-16T15:41:38Z					cellular_component											owl:Class	
GO:0061763	biolink:NamedThing	multivesicular body-lysosome fusion	The organelle membrane fusion process in which the membrane of a multivesicular body fuses with a lysosome to create a hybrid organelle.	tmpzr1t_l9r_go_relaxed.owl	fusion of multivesicular body to lysosome|MVB-lysosome fusion|fusion of MVB to lysosome							dph	2016-04-15T07:12:40Z					biological_process											owl:Class	
GO:1903012	biolink:NamedThing	positive regulation of bone development	Any process that activates or increases the frequency, rate or extent of bone development.	tmpzr1t_l9r_go_relaxed.owl	activation of bone development|up-regulation of bone development|upregulation of bone development|up regulation of bone development							mr	2014-05-13T22:42:06Z					biological_process											owl:Class	
GO:0060348	biolink:NamedThing	bone development	The process whose specific outcome is the progression of bone over time, from its formation to the mature structure. Bone is the hard skeletal connective tissue consisting of both mineral and cellular components.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1905864	biolink:NamedThing	regulation of Atg1/ULK1 kinase complex assembly	Any process that modulates the frequency, rate or extent of Atg1/ULK1 kinase complex assembly.	tmpzr1t_l9r_go_relaxed.owl	regulation of ULK1 signaling complex assembly|regulation of ULK1-ATG13-FIP200 complex assembly|regulation of ATG1/ULK1 kinase complex formation|regulation of ULK1-ATG13-RB1CC1 complex formation|regulation of ULK1 signaling complex formation|regulation of ATG1 kinase complex formation|regulation of ATG1-ATG13 complex formation|regulation of Atg1p signalling complex formation|regulation of ULK1-ATG13-RB1CC1 complex assembly|regulation of ULK1-ATG13-FIP200 complex formation|regulation of ATG1/ULK1 signaling complex formation|regulation of ATG1-ATG13 complex assembly|regulation of Atg1p signalling complex assembly|regulation of ATG1/ULK1 signaling complex assembly|regulation of ATG1 kinase complex assembly							pr	2017-01-26T13:23:26Z					biological_process											owl:Class	
GO:1904745	biolink:NamedThing	Atg1/ULK1 kinase complex assembly	The aggregation, arrangement and bonding together of a set of components to form an Atg1/UKL1 kinase complex.	tmpzr1t_l9r_go_relaxed.owl	Atg1p signalling complex assembly|ULK1-ATG13-FIP200 complex formation|ATG1-ATG13 complex formation|ULK1-ATG13-FIP200 complex assembly|Atg1p signalling complex formation|ULK1 signaling complex assembly|ATG1-ATG13 complex assembly|ATG1/ULK1 signaling complex formation|ULK1 signaling complex formation|ATG1/ULK1 kinase complex formation|ATG1 kinase complex formation|ATG1 kinase complex assembly|ULK1-ATG13-RB1CC1 complex formation|ULK1-ATG13-RB1CC1 complex assembly|ATG1/ULK1 signaling complex assembly							dph	2015-10-19T12:33:08Z					biological_process											owl:Class	
GO:1901082	biolink:NamedThing	positive regulation of relaxation of smooth muscle	Any process that activates or increases the frequency, rate or extent of relaxation of smooth muscle.	tmpzr1t_l9r_go_relaxed.owl	upregulation of smooth muscle relaxation|positive regulation of smooth muscle relaxation|activation of smooth muscle relaxation|upregulation of relaxation of smooth muscle|up-regulation of relaxation of smooth muscle|up regulation of smooth muscle relaxation|up-regulation of smooth muscle relaxation|up regulation of relaxation of smooth muscle|activation of relaxation of smooth muscle							jl	2012-07-04T10:45:39Z					biological_process											owl:Class	
GO:0005632	biolink:NamedThing	inner layer of spore wall	Either of the two innermost layers of the spore wall, as described in Saccharomyces.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0005619	biolink:NamedThing	ascospore wall	The specialized cell wall of the ascospore (spore), which is the product of meiotic division. Examples of this component are found in Fungi.	tmpzr1t_l9r_go_relaxed.owl	fungal-type spore wall													cellular_component											owl:Class	
GO:0048344	biolink:NamedThing	paraxial mesodermal cell fate determination	The process in which a cell becomes capable of differentiating autonomously into a paraxial mesoderm cell regardless of its environment; upon determination, the cell fate cannot be reversed.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0048343	biolink:NamedThing	paraxial mesodermal cell fate commitment	The process in which a cell becomes committed to become a paraxial mesoderm cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1902648	biolink:NamedThing	positive regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process	Any process that activates or increases the frequency, rate or extent of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	up regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate synthesis|positive regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate formation|positive regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate anabolism|activation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process|upregulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate anabolism|up regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate formation|upregulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthesis|up-regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process|upregulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate formation|positive regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate synthesis|up-regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate anabolism|up regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate anabolism|up-regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthesis|upregulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process|activation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate synthesis|activation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthesis|up regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthesis|activation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate formation|up-regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate synthesis|up-regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate formation|upregulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate synthesis|up regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process|positive regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthesis|activation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate anabolism							di	2014-01-21T17:58:15Z					biological_process											owl:Class	
GO:0036369	biolink:NamedThing	transcription factor catabolic process	The chemical reactions and pathways resulting in the breakdown of a sequence-specific DNA-binding transcription factor by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome.	tmpzr1t_l9r_go_relaxed.owl	sequence-specific DNA binding transcription factor catabolic process|transcription factor breakdown|proteasome-mediated transcription factor catabolism|transcription factor catabolism|transcription factor degradation							bf	2012-10-05T10:53:55Z					biological_process											owl:Class	
GO:0005839	biolink:NamedThing	proteasome core complex	A multisubunit barrel shaped endoprotease complex, which is the core of the proteasome complex.	tmpzr1t_l9r_go_relaxed.owl	20S proteasome|macropain|20S core complex|PA28gamma-20S proteasome											GO:0000503		cellular_component											owl:Class	
GO:0061329	biolink:NamedThing	Malpighian tubule principal cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a Malpighian tubule principal cell. A Malpighian tubule principal cell is an epithelial secretory cell that transports cations into the lumen of the tubule.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-09-28T01:26:33Z					biological_process											owl:Class	
GO:0000785	biolink:NamedThing	chromatin	The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome.	tmpzr1t_l9r_go_relaxed.owl	chromosome scaffold|cytoplasmic chromatin|nuclear chromatin				NIF_Subcellular:sao1615953555	Chromosomes include parts that are not part of the chromatin. Examples include the kinetochore.						GO:0005717|GO:0000789|GO:0000790		cellular_component											owl:Class	
GO:1903769	biolink:NamedThing	negative regulation of cell proliferation in bone marrow	Any process that stops, prevents or reduces the frequency, rate or extent of cell proliferation in bone marrow.	tmpzr1t_l9r_go_relaxed.owl	inhibition of cell proliferation in bone marrow|down-regulation of cell proliferation in bone marrow|down-regulation of bone marrow cell proliferation|down regulation of bone marrow cell proliferation|downregulation of bone marrow cell proliferation|inhibition of bone marrow cell proliferation|down regulation of cell proliferation in bone marrow|negative regulation of bone marrow cell proliferation|downregulation of cell proliferation in bone marrow							sl	2014-12-29T19:46:26Z					biological_process											owl:Class	
GO:0071838	biolink:NamedThing	cell proliferation in bone marrow	The multiplication or reproduction of cells, resulting in the expansion of a cell population in the bone marrow.	tmpzr1t_l9r_go_relaxed.owl	bone marrow cell proliferation							mah	2010-09-10T12:15:41Z					biological_process											owl:Class	
GO:0007392	biolink:NamedThing	initiation of dorsal closure	Events that occur at the start of dorsal closure.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0010206	biolink:NamedThing	photosystem II repair	Proteolysis of the damaged D1 protein and re-assembly of a new D1 subunit in the photosystem II following photoinhibition.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0009765	biolink:NamedThing	photosynthesis, light harvesting	Absorption and transfer of the energy absorbed from light photons between photosystem reaction centers.	tmpzr1t_l9r_go_relaxed.owl	energy dissipation													biological_process											owl:Class	
GO:0003215	biolink:NamedThing	cardiac right ventricle morphogenesis	The process in which the right cardiac ventricle is generated and organized.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-10-13T09:50:57Z					biological_process											owl:Class	
GO:0004708	biolink:NamedThing	MAP kinase kinase activity	Catalysis of the concomitant phosphorylation of threonine (T) and tyrosine (Y) residues in a Thr-Glu-Tyr (TEY) thiolester sequence in a MAP kinase (MAPK) substrate.	tmpzr1t_l9r_go_relaxed.owl	MEK2|MAP2K|MKK7|mitogen-activated protein kinase kinase activity|MEK1|MAPK activator activity|MAP kinase kinase 7 activity|STK27|ERK activator kinase activity|MAPKK activity|MKK4|MAPKK1|MAP kinase or ERK kinase activity|MKK|ATP:protein phosphotransferase (MAPKKK-activated) activity|MAP kinase kinase 4 activity|MAPKK|MKK2|MEK activity|MKK6				Reactome:R-HSA-1247960|Reactome:R-HSA-3238999|Reactome:R-HSA-448951|EC:2.7.12.2|Reactome:R-HSA-450333|MetaCyc:2.7.12.2-RXN|Reactome:R-HSA-5218804									molecular_function											owl:Class	
GO:1990691	biolink:NamedThing	cis-Golgi-derived vesicle fusion with Golgi medial cisterna membrane	The joining of the lipid bilayer membrane around a cis-Golgi-derived vesicle to the lipid bilayer membrane around the medial-Golgi cisterna. Vesicles are involved in anterograde transport.	tmpzr1t_l9r_go_relaxed.owl	cis-Golgi-derived vesicle fusion with medial-Golgi cisterna membrane							bhm	2015-03-12T09:51:01Z					biological_process											owl:Class	
GO:0048219	biolink:NamedThing	inter-Golgi cisterna vesicle-mediated transport	The directed movement of substances from one Golgi cisterna to another, mediated by small transport vesicles.	tmpzr1t_l9r_go_relaxed.owl	inter-Golgi cisterna transport													biological_process											owl:Class	
GO:0002548	biolink:NamedThing	monocyte chemotaxis	The movement of a monocyte in response to an external stimulus.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1905759	biolink:NamedThing	post-anaphase array microtubule	Any microtubule that is part of a post-anaphase microtubule array.	tmpzr1t_l9r_go_relaxed.owl	microtubulus of PAA|microtubuli of post-anaphase microtubule array|microtubule of post-anaphase array|microtubulus of post-anaphase array|microtubule of post-anaphase microtubule array|microtubuli of PAA|neurotubule of PAA|neurotubule of post-anaphase microtubule array|microtubulus of post-anaphase microtubule array|microtubule of PAA|neurotubule of post-anaphase array|microtubuli of post-anaphase array							dos	2016-12-12T18:36:53Z					cellular_component											owl:Class	
GO:1990295	biolink:NamedThing	post-anaphase microtubule array	A cytoskeletal part that consists of an array of microtubules and associated molecules that forms at the end of anaphase, and in which microtubules are nucleated from an equatorial microtubule organizing center.	tmpzr1t_l9r_go_relaxed.owl	post-anaphase array|PAA					The best-characterized example is found in the fission yeast Schizosaccharomyces pombe. The eMTOC is cortical, but the post-anaphase array microtubules are not exclusively cortical.		mah	2014-02-20T13:54:23Z					cellular_component											owl:Class	
GO:0140463	biolink:NamedThing	chromatin-protein adaptor	The binding activity of a molecule that brings together a protein or a protein complex with a nucleosome, to establish or maintain the chromatin localization of the protein, or protein complex.	tmpzr1t_l9r_go_relaxed.owl	chromatin adaptor|chromatin recruitment|chromatin adaptor activity|protein-chromatin adaptor activity|chromatin receptor	https://github.com/geneontology/go-ontology/issues/17064						pg	2020-05-08T12:31:39Z					molecular_function											owl:Class	
GO:0003682	biolink:NamedThing	chromatin binding	Binding to chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.	tmpzr1t_l9r_go_relaxed.owl	microtubule/chromatin interaction|lamin/chromatin binding|nuclear membrane vesicle binding to chromatin													molecular_function											owl:Class	
GO:1901296	biolink:NamedThing	negative regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment	Any process that stops, prevents or reduces the frequency, rate or extent of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment.	tmpzr1t_l9r_go_relaxed.owl	downregulation of canonical Wnt receptor signalling pathway involved in cardiac muscle cell fate commitment|negative regulation of canonical Wnt receptor signaling pathway involved in cardiac muscle cell fate commitment|negative regulation of canonical Wnt-activated signaling pathway involved in cardiac muscle cell fate commitment|down regulation of canonical Wnt receptor signalling pathway involved in cardiac muscle cell fate commitment|inhibition of canonical Wnt receptor signaling pathway involved in cardiac muscle cell fate commitment|downregulation of canonical Wnt receptor signaling pathway involved in cardiac muscle cell fate commitment|down regulation of canonical Wnt receptor signaling pathway involved in cardiac muscle cell fate commitment|down-regulation of canonical Wnt receptor signaling pathway involved in cardiac muscle cell fate commitment|inhibition of canonical Wnt receptor signalling pathway involved in cardiac muscle cell fate commitment|negative regulation of canonical Wnt receptor signalling pathway involved in cardiac muscle cell fate commitment|down-regulation of canonical Wnt receptor signalling pathway involved in cardiac muscle cell fate commitment							vk	2012-08-21T09:06:52Z					biological_process											owl:Class	
GO:0090313	biolink:NamedThing	regulation of protein targeting to membrane	Any process that modulates the frequency, rate or extent of the process of directing proteins towards a membrane, usually using signals contained within the protein.	tmpzr1t_l9r_go_relaxed.owl								tb	2010-04-16T03:42:22Z					biological_process											owl:Class	
GO:0006612	biolink:NamedThing	protein targeting to membrane	The process of directing proteins towards a membrane, usually using signals contained within the protein.	tmpzr1t_l9r_go_relaxed.owl	protein membrane targeting|protein-membrane targeting													biological_process											owl:Class	
GO:0031138	biolink:NamedThing	negative regulation of conjugation with cellular fusion	Any process that decreases the rate or frequency of conjugation with cellular fusion.	tmpzr1t_l9r_go_relaxed.owl	inhibition of conjugation with cellular fusion|downregulation of conjugation with cellular fusion|down-regulation of conjugation with cellular fusion|down regulation of conjugation with cellular fusion													biological_process											owl:Class	
GO:0000747	biolink:NamedThing	conjugation with cellular fusion	A conjugation process that results in the union of cellular and genetic information from compatible mating types. An example of this process is found in Saccharomyces cerevisiae.	tmpzr1t_l9r_go_relaxed.owl	cell fusion|mating											GO:0030477|GO:0007333|GO:0007322|GO:0030461		biological_process											owl:Class	
GO:1905612	biolink:NamedThing	positive regulation of mRNA cap binding	Any process that activates or increases the frequency, rate or extent of mRNA cap binding.	tmpzr1t_l9r_go_relaxed.owl	up regulation of mRNA cap binding|activation of mRNA cap binding|upregulation of mRNA cap binding|up-regulation of mRNA cap binding							bc	2016-10-28T11:27:43Z					biological_process											owl:Class	
GO:0098578	biolink:NamedThing	condensed chromatin of inactivated sex chromosome	A condensed form of chromatin that is associated with an inactivated sex chromosome and which is responsible for its inactivation.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0098577	biolink:NamedThing	inactive sex chromosome	A sex chromosome that has been inactivated.	tmpzr1t_l9r_go_relaxed.owl	inactivated sex chromosome													cellular_component											owl:Class	
GO:0004879	biolink:NamedThing	nuclear receptor activity	A DNA-binding transcription factor activity regulated by binding to a ligand that modulates the transcription of specific gene sets transcribed by RNA polymerase II. Nuclear receptor ligands are usually lipid-based (such as a steroid hormone) and the binding of the ligand to its receptor often occurs in the cytoplasm, which leads to its tranlocation to the nucleus.	tmpzr1t_l9r_go_relaxed.owl	ligand-dependent nuclear receptor activity|RXR|vitamin A receptor activity|RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding|estrogen nuclear receptor activity|androgen receptor activity|retinoic acid receptor activity|calcitriol receptor activity|vitamin D receptor activity|thyroid hormone receptor activity|RNA polymerase II transcription factor activity, glucocorticoid-activated sequence-specific DNA binding|1,25-(OH)2D3 receptor activity|ecdysteroid hormone receptor activity|nuclear hormone receptor|RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding|juvenile hormone receptor activity|retinoid-X receptor activity|ligand-dependent transcription factor activity|9-cis retinoic acid receptor activity|vitamin D3 receptor activity|ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity|glucocorticoid receptor activity	https://github.com/geneontology/go-ontology/issues/20253|https://github.com/geneontology/go-ontology/issues/19518				Usage guidance: Nuclear receptors are a protein family defined by the presence of a C4-type zinc finger DNA-binding domain and a ligand binding domain. For nuclear receptors, the DNA binding motif is most often referred to as a response element. GO:0004879 is intended for annotation of nuclear receptors that regulate transcription by binding directly to DNA. When the nuclear receptor functions by binding to other transcription factors or transcription factor complexes, consider instead annotating to 'GO:0030374 ; nuclear receptor transcription coactivator activity' or GO:0140536 ; nuclear corepressor activity.						GO:0004886|GO:0004884|GO:0038052|GO:0038050|GO:0004882|GO:0003708|GO:0004880|GO:0038051|GO:0008434|GO:0004887		molecular_function											owl:Class	
GO:0044576	biolink:NamedThing	pentose catabolic process to ethanol	The anaerobic chemical reactions and pathways resulting in the breakdown of a pentose, any monosaccharide with a chain of five carbons, where one of the resulting products is ethanol.	tmpzr1t_l9r_go_relaxed.owl	pentose catabolism to ethanol							jl	2012-04-19T03:46:37Z					biological_process											owl:Class	
GO:0031020	biolink:NamedThing	plastid mRNA editing complex	An mRNA editing complex found in a plastid.	tmpzr1t_l9r_go_relaxed.owl	plastid editosome													cellular_component											owl:Class	
GO:0072035	biolink:NamedThing	pre-tubular aggregate formation	The cell adhesion process in which mesenchyme cells adhere to one another in the initial stages of the formation of the pre-tubular aggregate, the earliest recognizable structure of the kidney.	tmpzr1t_l9r_go_relaxed.owl	mesenchymal cell condensation involved in renal vesicle formation|nephron epithelium formation							mah	2010-01-25T03:03:10Z					biological_process											owl:Class	
GO:0072033	biolink:NamedThing	renal vesicle formation	The developmental process pertaining to the initial formation of the renal vesicle from condensed mesenchymal cells. The renal vesicle is the primordial structure of the nephron epithelium, and is formed by the condensation of mesenchymal cells.	tmpzr1t_l9r_go_relaxed.owl	nephron epithelium formation							mah	2010-01-25T02:57:03Z					biological_process											owl:Class	
GO:0044280	biolink:NamedThing	subplasmalemmal coating	Electron dense material observed coating the cytoplasmic face of the plasma membrane in certain regions of a neuron, e.g., the axon initial segment; the nodal membrane at the Node of Ranvier.	tmpzr1t_l9r_go_relaxed.owl					NIF_Subcellular:sao1938587839			jl	2010-01-14T03:58:38Z					cellular_component											owl:Class	
GO:0031234	biolink:NamedThing	extrinsic component of cytoplasmic side of plasma membrane	The component of a plasma membrane consisting of gene products and protein complexes that are loosely bound to its cytoplasmic surface, but not integrated into the hydrophobic region.	tmpzr1t_l9r_go_relaxed.owl	extrinsic to internal side of plasma membrane|extrinsic to cytoplasmic side of plasma membrane|extrinsic to internal leaflet of plasma membrane	https://github.com/geneontology/go-ontology/issues/22186				Consider also annotating to 'cell cortex ; GO:0005938'.								cellular_component											owl:Class	
GO:0015117	biolink:NamedThing	thiosulfate transmembrane transporter activity	Enables the transfer of thiosulfate ions, S2O3(2-), from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	thiosulphate transporter activity|thiosulfate permease activity				RHEA:32807									molecular_function											owl:Class	
GO:0015709	biolink:NamedThing	thiosulfate transport	The directed movement of thiosulfate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	thiosulphate transport													biological_process											owl:Class	
GO:0070227	biolink:NamedThing	lymphocyte apoptotic process	Any apoptotic process in a lymphocyte, a leukocyte commonly found in the blood and lymph that has the characteristics of a large nucleus, a neutral staining cytoplasm, and prominent heterochromatin.	tmpzr1t_l9r_go_relaxed.owl	lymphocyte apoptosis					Note that a lymphocyte is a cell of the B cell, T cell, or natural killer cell lineage (CL:0000542).								biological_process											owl:Class	
GO:0003167	biolink:NamedThing	atrioventricular bundle cell differentiation	The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cell of the atrioventricular bundle. These cells are specialized cardiomyocytes that transmit signals from the AV node to the cardiac Purkinje fibers.	tmpzr1t_l9r_go_relaxed.owl	AV bundle cell differentiation							dph	2009-10-01T02:48:23Z					biological_process											owl:Class	
GO:0003166	biolink:NamedThing	bundle of His development	The process whose specific outcome is the progression of the bundle of His over time, from its formation to the mature structure. The bundle of His is part of the His-Purkinje system that transmits signals from the AV node to the cardiac Purkinje fibers.	tmpzr1t_l9r_go_relaxed.owl	atrioventricular bundle development							dph	2009-10-01T02:08:43Z					biological_process											owl:Class	
GO:1901918	biolink:NamedThing	negative regulation of exoribonuclease activity	Any process that stops, prevents or reduces the frequency, rate or extent of exoribonuclease activity.	tmpzr1t_l9r_go_relaxed.owl	down regulation of exoribonuclease activity|down-regulation of exoribonuclease activity|inhibition of exoribonuclease activity|downregulation of exoribonuclease activity							rb	2013-02-15T00:58:03Z					biological_process											owl:Class	
GO:0004532	biolink:NamedThing	exoribonuclease activity	Catalysis of the sequential cleavage of mononucleotides from a free 5' or 3' terminus of an RNA molecule.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-429961									molecular_function											owl:Class	
GO:0018024	biolink:NamedThing	histone-lysine N-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + histone L-lysine = S-adenosyl-L-homocysteine + histone N6-methyl-L-lysine. The methylation of peptidyl-lysine in histones forms N6-methyl-L-lysine, N6,N6-dimethyl-L-lysine and N6,N6,N6-trimethyl-L-lysine derivatives.	tmpzr1t_l9r_go_relaxed.owl	histone H1-specific S-adenosylmethionine:protein-lysine N-methyltransferase activity|S-adenosyl-L-methionine:histone-L-lysine N6-methyltransferase activity|protein methyltransferase II activity|S-adenosyl-L-methionine:histone-L-lysine 6-N-methyltransferase activity|protein methylase 3 activity|protein methylase III activity|protein (lysine) methyltransferase activity|histone-lysine N-methylase activity				Reactome:R-HSA-5638333|Reactome:R-HSA-5649801|MetaCyc:HISTONE-LYSINE-N-METHYLTRANSFERASE-RXN|Reactome:R-HSA-3788748|Reactome:R-HSA-5651654|Reactome:R-HSA-5638332|Reactome:R-HSA-5423038|RESID:AA0074|RESID:AA0075|Reactome:R-HSA-5634729|Reactome:R-HSA-5649799|Reactome:R-HSA-5638141|Reactome:R-HSA-5637686|Reactome:R-HSA-5649800|Reactome:R-HSA-5638157|Reactome:R-HSA-5649802|RHEA:10024|Reactome:R-HSA-5651657|Reactome:R-HSA-4827382|RESID:AA0076|Reactome:R-HSA-5634750|Reactome:R-HSA-5159245|EC:2.1.1.354|Reactome:R-HSA-5649764|Reactome:R-HSA-5244692|Reactome:R-HSA-3788745|Reactome:R-HSA-5634802|Reactome:R-HSA-4827383									molecular_function											owl:Class	
GO:0019253	biolink:NamedThing	reductive pentose-phosphate cycle	The fixation of carbon dioxide (CO2) as glucose in the chloroplasts of C3 plants; uses ATP and NADPH formed in the light reactions of photosynthesis; carbon dioxide reacts with ribulose 1,5-bisphosphate (catalyzed by the function of ribulose-bisphosphate carboxylase) to yield two molecules of 3-phosphoglycerate; these are then phosphorylated by ATP to 1,3-bisphosphateglyceraldehyde which, in turn, is then reduced by NADPH to glyceraldehyde 3-phosphate. The glyceraldehyde 3-phosphate is converted to fructose 5-phosphate and ribulose 5-phosphate by aldolase and other enzymes; the ribulose 5-phosphate is phosphorylated by ATP to ribulose 1,5-bisphosphate.	tmpzr1t_l9r_go_relaxed.owl	C3 photosynthesis|Calvin cycle				MetaCyc:CALVIN-PWY	See also the molecular function term 'ribulose-bisphosphate carboxylase activity ; GO:0016984'.								biological_process											owl:Class	
GO:0015977	biolink:NamedThing	carbon fixation	A metabolic process in which carbon (usually derived from carbon dioxide) is incorporated into organic compounds (usually carbohydrates).	tmpzr1t_l9r_go_relaxed.owl	carbon dioxide fixation|autotrophy|autotrophic CO2 fixation pathway|autotrophic CO2 fixation				Wikipedia:Carbon_fixation									biological_process											owl:Class	
GO:0035991	biolink:NamedThing	nitric oxide sensor activity	Binding to and responding, e.g. by conformational change, to changes in the cellular level of nitric oxide (NO).	tmpzr1t_l9r_go_relaxed.owl	NO sensor activity							bf	2011-08-26T04:32:16Z					molecular_function											owl:Class	
GO:0071731	biolink:NamedThing	response to nitric oxide	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitric oxide stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-03-17T04:03:38Z					biological_process											owl:Class	
GO:1902774	biolink:NamedThing	late endosome to lysosome transport	The directed movement of substances from late endosome to lysosome.	tmpzr1t_l9r_go_relaxed.owl	prevacuolar compartment to lysosome transport					an example of this is snapin in mouse (Q9Z266) in PMID:20920792 inferred from mutant phenotype		pad	2014-03-17T16:32:36Z					biological_process											owl:Class	
GO:1905678	biolink:NamedThing	negative regulation of adaptive immune effector response	Any process that stops, prevents or reduces the frequency, rate or extent of adaptive immune effector response.	tmpzr1t_l9r_go_relaxed.owl	inhibition of adaptive immune effector response|down-regulation of adaptive immune effector response|downregulation of adaptive immune effector response|down regulation of adaptive immune effector response							tb	2016-11-11T22:25:05Z					biological_process											owl:Class	
GO:0090718	biolink:NamedThing	adaptive immune effector response	An adaptive immune response that involves one or more immune effector processes and takes place during the effector phase of the adaptive immune response.	tmpzr1t_l9r_go_relaxed.owl								tb	2016-11-11T12:37:26Z					biological_process											owl:Class	
GO:0070918	biolink:NamedThing	production of small RNA involved in gene silencing by RNA	The process in which a double-stranded RNA precursor is processed into short (20-30 nt) fragments. RNA cleavage is catalyzed by a Dicer endonuclease.	tmpzr1t_l9r_go_relaxed.owl	gene silencing by RNA, production of guide RNA|gene silencing by RNA, production of small RNA							mah	2009-09-11T03:32:19Z					biological_process											owl:Class	
GO:0031047	biolink:NamedThing	gene silencing by RNA	Any process in which RNA molecules inactivate expression of target genes.	tmpzr1t_l9r_go_relaxed.owl	RNA-mediated gene silencing	https://github.com/geneontology/go-ontology/issues/22202												biological_process											owl:Class	
GO:2000217	biolink:NamedThing	regulation of invasive growth in response to glucose limitation	Any process that modulates the frequency, rate or extent of invasive growth in response to glucose limitation.	tmpzr1t_l9r_go_relaxed.owl	regulation of colony morphology							mah	2010-11-03T04:35:56Z					biological_process											owl:Class	
GO:0001403	biolink:NamedThing	invasive growth in response to glucose limitation	A growth pattern exhibited by budding haploid cells under certain growth conditions, in which cells retain the typical axial budding pattern of haploids, but become elongated and fail to separate after division; during growth on a solid substrate, this results in penetration of cells into the agar medium. An example of this process is found in Saccharomyces cerevisiae.	tmpzr1t_l9r_go_relaxed.owl	colony morphology					Note that this term should not be used to describe the invasion of host tissues by pathogenic organisms, which is described by the biological process term 'entry into host ; GO:0044409', nor should it be used to describe growth of diseased cells of an organism into the surrounding normal tissue, which is outside of the scope of GO.								biological_process											owl:Class	
GO:0010525	biolink:NamedThing	regulation of transposition, RNA-mediated	Any process that modulates the frequency, rate or extent of RNA-mediated transposition. RNA-mediated transposition is a type of transpositional recombination which occurs via an RNA intermediate.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1990716	biolink:NamedThing	axonemal central apparatus	Part of the 9+2 axoneme, that occurs in most motile cilia, consisting of the pair of two single central microtubules and their associated structures which include the central pair projections, the central pair bridges linking the two tubules, and the central pair caps which are attached to the distal or plus ends of the microtubules.	tmpzr1t_l9r_go_relaxed.owl								krc	2015-03-27T22:33:23Z					cellular_component											owl:Class	
GO:0048382	biolink:NamedThing	mesendoderm development	The process whose specific outcome is the progression of the mesendoderm over time, from its formation to the mature structure. In animal embryos, mesendoderm development gives rise to both mesoderm and endoderm tissues.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0110030	biolink:NamedThing	regulation of G2/MI transition of meiotic cell cycle	Any signalling pathway that modulates the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to MI phase of the meiotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl								kmv	2017-07-12T19:02:19Z					biological_process											owl:Class	
GO:0035599	biolink:NamedThing	aspartic acid methylthiotransferase activity	Catalysis of the methylthiolation (-SCH3 addition) of the beta-carbon of peptidyl-aspartic acid to form peptidyl-L-beta-methylthioaspartic acid.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0232	Note that peptidyl-L-beta-methylthioaspartic acid is typical of bacterial ribosomal protein S12.		bf	2010-11-12T01:31:23Z					molecular_function											owl:Class	
GO:1905643	biolink:NamedThing	positive regulation of DNA methylation	Any process that activates or increases the frequency, rate or extent of DNA methylation.	tmpzr1t_l9r_go_relaxed.owl	activation of DNA methylation|up-regulation of DNA methylation|upregulation of DNA methylation|up regulation of DNA methylation							bc	2016-11-04T16:43:22Z					biological_process											owl:Class	
GO:0006306	biolink:NamedThing	DNA methylation	The covalent transfer of a methyl group to either N-6 of adenine or C-5 or N-4 of cytosine.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:DNA_methylation									biological_process											owl:Class	
GO:0044017	biolink:NamedThing	histone acetyltransferase activity (H3-K27 specific)	Catalysis of the reaction: acetyl-CoA + histone H3 L-lysine (position 27) = CoA + histone H3 N6-acetyl-L-lysine (position 27).	tmpzr1t_l9r_go_relaxed.owl	histone lysine N-acetyltransferase activity (H3-K27 specific)													molecular_function											owl:Class	
GO:0043974	biolink:NamedThing	histone H3-K27 acetylation	The modification of histone H3 by the addition of an acetyl group to a lysine residue at position 27 of the histone.	tmpzr1t_l9r_go_relaxed.owl	histone H3K27 acetylation|histone H3 acetylation at K27													biological_process											owl:Class	
GO:1905287	biolink:NamedThing	positive regulation of G2/M transition of mitotic cell cycle involved in cellular response to nitrogen starvation	Any positive regulation of G2/M transition of mitotic cell cycle that is involved in cellular response to nitrogen starvation.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of mitotic entry involved in cellular response to nitrogen starvation							al	2016-06-21T17:19:33Z					biological_process											owl:Class	
GO:0006995	biolink:NamedThing	cellular response to nitrogen starvation	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of nitrogen.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0008076	biolink:NamedThing	voltage-gated potassium channel complex	A protein complex that forms a transmembrane channel through which potassium ions may cross a cell membrane in response to changes in membrane potential.	tmpzr1t_l9r_go_relaxed.owl	voltage-sensitive potassium channel complex|voltage gated potassium channel complex|voltage-dependent potassium channel complex				NIF_Subcellular:sao371494298									cellular_component											owl:Class	
GO:0003142	biolink:NamedThing	cardiogenic plate morphogenesis	The process in which the anatomical structures of the cardiogenic plate are generated and organized. The cardiogenic plate is the first recognizable structure derived from the heart field.	tmpzr1t_l9r_go_relaxed.owl	cardiac crescent morphogenesis							tb	2009-09-22T04:12:18Z					biological_process											owl:Class	
GO:0032201	biolink:NamedThing	telomere maintenance via semi-conservative replication	The process in which telomeric DNA is synthesized semi-conservatively by the conventional replication machinery and telomeric accessory factors as part of cell cycle DNA replication.	tmpzr1t_l9r_go_relaxed.owl	telomeric replication fork progression|equal telomere replication|telomeric fork progression													biological_process											owl:Class	
GO:0071218	biolink:NamedThing	cellular response to misfolded protein	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a misfolded protein stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-12-03T01:17:46Z					biological_process											owl:Class	
GO:0039504	biolink:NamedThing	suppression by virus of host adaptive immune response	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of the adaptive immune response of the host organism, an immune response based on directed amplification of specific receptors for antigen produced through a somatic diversification process, and allowing for enhanced response to subsequent exposures to the same antigen (immunological memory).	tmpzr1t_l9r_go_relaxed.owl	negative regulation by virus of host adaptive immune response|negative regulation by virus of host adaptive immunity|inhibition of host adaptive immune response by virus|suppression by virus of host acquired immune response							bf	2011-05-11T04:41:54Z					biological_process											owl:Class	
GO:0002250	biolink:NamedThing	adaptive immune response	An immune response mediated by cells expressing specific receptors for antigen produced through a somatic diversification process, and allowing for an enhanced secondary response to subsequent exposures to the same antigen (immunological memory).	tmpzr1t_l9r_go_relaxed.owl	immune memory response|acquired immune response				Wikipedia:Adaptive_immune_system									biological_process											owl:Class	
GO:0075279	biolink:NamedThing	uredinium development	The process that leads to the formation of a uredinium, a reddish, pustule-like structure formed by a rust fungus and consisting of uredospores.	tmpzr1t_l9r_go_relaxed.owl	development of uredium													biological_process											owl:Class	
GO:0045444	biolink:NamedThing	fat cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of an adipocyte, an animal connective tissue cell specialized for the synthesis and storage of fat.	tmpzr1t_l9r_go_relaxed.owl	adipocyte cell differentiation|adipogenesis|adipose cell differentiation|adipocyte differentiation													biological_process											owl:Class	
GO:1902952	biolink:NamedThing	positive regulation of dendritic spine maintenance	Any process that activates or increases the frequency, rate or extent of dendritic spine maintenance.	tmpzr1t_l9r_go_relaxed.owl	up regulation of dendritic spine maintenance|up-regulation of dendritic spine maintenance|upregulation of dendritic spine maintenance|activation of dendritic spine maintenance							sjp	2014-05-02T08:48:59Z					biological_process											owl:Class	
GO:0032612	biolink:NamedThing	interleukin-1 production	The appearance of interleukin-1 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	tmpzr1t_l9r_go_relaxed.owl	interleukin-1 secretion|IL-1 production|interleukin-1 biosynthetic process											GO:0050701|GO:0042222		biological_process											owl:Class	
GO:1905259	biolink:NamedThing	negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway	Any process that stops, prevents or reduces the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to nitrosative stress.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of nitrosative stress-induced apoptosis|inhibition of nitrosative stress-induced apoptosis|downregulation of nitrosative stress-induced apoptosis|down-regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway|down-regulation of nitrosative stress-induced apoptosis|down regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway|down regulation of nitrosative stress-induced apoptosis|down-regulation of intrinsic apoptotic signaling pathway in response to nitrosative stress|downregulation of intrinsic apoptotic signaling pathway in response to nitrosative stress|inhibition of nitrosative stress-induced intrinsic apoptotic signaling pathway|down regulation of intrinsic apoptotic signaling pathway in response to nitrosative stress|inhibition of intrinsic apoptotic signaling pathway in response to nitrosative stress|downregulation of nitrosative stress-induced intrinsic apoptotic signaling pathway|negative regulation of intrinsic apoptotic signaling pathway in response to nitrosative stress							bf	2016-06-13T17:05:07Z					biological_process											owl:Class	
GO:1990442	biolink:NamedThing	intrinsic apoptotic signaling pathway in response to nitrosative stress	A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced in response to nitrosative stress; a state often resulting from exposure to high levels of nitric oxide (NO) or the highly reactive oxidant peroxynitrite, which is produced following interaction of NO with superoxide anions.	tmpzr1t_l9r_go_relaxed.owl	nitrosative stress-induced apoptosis|nitrosative stress-induced intrinsic apoptotic signaling pathway							bf	2014-07-31T14:28:16Z					biological_process											owl:Class	
GO:0051932	biolink:NamedThing	synaptic transmission, GABAergic	The vesicular release of  gamma-aminobutyric acid (GABA). from a presynapse, across a chemical synapse, the subsequent activation of GABA receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse.	tmpzr1t_l9r_go_relaxed.owl	synaptic transmission, gamma-aminobutyric acid-ergic|synaptic transmission, GABA mediated|synaptic transmission, gamma-aminobutyric acid mediated|GABAergic synaptic transmission													biological_process											owl:Class	
GO:0048392	biolink:NamedThing	intermediate mesodermal cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of an intermediate mesoderm cell.	tmpzr1t_l9r_go_relaxed.owl	intermediate mesoderm cell differentiation													biological_process											owl:Class	
GO:1904424	biolink:NamedThing	regulation of GTP binding	Any process that modulates the frequency, rate or extent of GTP binding.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-07-02T20:34:44Z					biological_process											owl:Class	
GO:0005525	biolink:NamedThing	GTP binding	Binding to GTP, guanosine triphosphate.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-167429									molecular_function											owl:Class	
GO:0061638	biolink:NamedThing	CENP-A containing chromatin	The specialized chromatin located in the centromeric core region or the entire centromeric region in organisms with point centromeres, which is enriched for CENP-A-containing nucleosomes. This chromatin forms a 3-dimensional structure which provides a platform for kinetochore assembly and microtubule attachment.	tmpzr1t_l9r_go_relaxed.owl	chromatin containing CENP-A|centromeric core region chromatin|nuclear CENP-A containing chromatin|centromeric core domain chromatin							dph	2014-08-20T14:06:35Z			GO:1904834		cellular_component											owl:Class	
GO:0034506	biolink:NamedThing	chromosome, centromeric core domain	The innermost portion of the centromeric region of a chromosome, encompassing the core region of a chromosome centromere and the proteins that bind to it.	tmpzr1t_l9r_go_relaxed.owl	chromosome, centric core region|chromosome, centromeric core region													cellular_component											owl:Class	
GO:1904606	biolink:NamedThing	fat cell apoptotic process	Any apoptotic process in a fat cell.	tmpzr1t_l9r_go_relaxed.owl	adipocyte apoptosis|fat cell apoptosis|adipose cell apoptotic process|adipose cell apoptosis|adipocyte apoptotic process							sl	2015-08-27T18:13:06Z					biological_process											owl:Class	
GO:0090656	biolink:NamedThing	t-circle formation	A telomere maintenance process that results in the formation of a telomeric circle, or t-circle. A t-circle is an extrachromosomal duplex or single-stranded circular DNA molecule composed of t-arrays. T-circles are involved in the control of telomere length via alternative-lengthening of telomeres (ALT) pathway and telomere rapid deletion (TRD).	tmpzr1t_l9r_go_relaxed.owl	telomeric circle formation							tb	2015-07-02T11:44:23Z					biological_process											owl:Class	
GO:0090737	biolink:NamedThing	telomere maintenance via telomere trimming	A process that contributes to the maintenance of proper telomeric length and structure via the activation of telomere shortening pathways that compensate telomerase-dependent excessive telomere elongation. Telomere attrition is mediated by a mechanism which involves the generation of single-stranded C-rich telomeric DNA, and the formation and removal of double-stranded telomeric circular DNA (T-circles). Telomere trimming is an independent pathway to recombination-mediated telomere elongation and the well-documented gradual telomere attrition that accompanies cellular replication.	tmpzr1t_l9r_go_relaxed.owl								tb	2017-02-07T16:51:24Z					biological_process											owl:Class	
GO:0048704	biolink:NamedThing	embryonic skeletal system morphogenesis	The process in which the anatomical structures of the skeleton are generated and organized during the embryonic phase.	tmpzr1t_l9r_go_relaxed.owl	embryonic skeletal morphogenesis													biological_process											owl:Class	
GO:0048706	biolink:NamedThing	embryonic skeletal system development	The process, occurring during the embryonic phase, whose specific outcome is the progression of the skeleton over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl	embryonic skeletal development													biological_process											owl:Class	
GO:0009736	biolink:NamedThing	cytokinin-activated signaling pathway	A series of molecular signals generated by the binding of a cytokinin to a receptor, and ending with regulation of a downstream cellular process, e.g. transcription.	tmpzr1t_l9r_go_relaxed.owl	cytokinin mediated signalling|cytokinin signaling|cytokinin mediated signaling pathway													biological_process											owl:Class	
GO:0071368	biolink:NamedThing	cellular response to cytokinin stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytokinin stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-12-11T03:13:47Z					biological_process											owl:Class	
GO:0060272	biolink:NamedThing	embryonic skeletal joint morphogenesis	The process in which the anatomical structures of skeletal joints are generated and organized during the embryonic phase. A skeletal joint is the connecting structure between the bones of the skeleton.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0072498	biolink:NamedThing	embryonic skeletal joint development	The process, occurring during the embryonic phase, whose specific outcome is the progression of the skeletal joints over time, from formation to mature structure.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-12-15T04:14:42Z					biological_process											owl:Class	
GO:1904708	biolink:NamedThing	regulation of granulosa cell apoptotic process	Any process that modulates the frequency, rate or extent of granulosa cell apoptotic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of granulosa cell apoptosis|regulation of granulosa cell of ovary apoptosis|regulation of granulosa cell of ovary apoptotic process							sl	2015-10-01T16:09:38Z					biological_process											owl:Class	
GO:1904700	biolink:NamedThing	granulosa cell apoptotic process	Any apoptotic process in a granulosa cell.	tmpzr1t_l9r_go_relaxed.owl	granulosa cell of ovary apoptotic process|granulosa cell apoptosis|granulosa cell of ovary apoptosis							sl	2015-09-30T21:29:54Z					biological_process											owl:Class	
GO:0097591	biolink:NamedThing	ventral disc lateral crest	Fibrillar repetitive structure surrounding the ventral disc edge in Giardia species (trophozoite stage). The composition of the lateral crest is not fully known yet.	tmpzr1t_l9r_go_relaxed.owl	lateral crest|ventral disk lateral crest					Due to the asymmetric nature of the Giardia trophozoite, this term is defined spatially as the trophozoite is viewed from the dorsal side, with the two nuclei dorsal to the ventral disc, and the ventral disc toward the anterior.		pr	2014-04-03T10:47:48Z					cellular_component											owl:Class	
GO:0097597	biolink:NamedThing	ventral disc	Specialized organelle found in Giardia species (trophozoite stage) and characterized by a spiral array of microtubules and microtubule-associated structures including dorsal microribbons and crossbridges. The edge of the ventral disc narrows into a lateral crest. The ventral disk mediates mechanical attachment of the trophozoite to the host's intestinal wall, and contains the contractile proteins actinin, alpha-actinin, myosin, and tropomyosin working towards contraction of the disk involved in adherence.	tmpzr1t_l9r_go_relaxed.owl	ventral disk|adhesive disc|ventral adhesive disc					Due to the asymmetric nature of the Giardia trophozoite, this term is defined spatially as the trophozoite is viewed from the dorsal side, with the two nuclei dorsal to the ventral disc, and the ventral disc toward the anterior.		pr	2014-04-03T11:29:58Z					cellular_component											owl:Class	
GO:0035751	biolink:NamedThing	regulation of lysosomal lumen pH	Any process that modulates the pH of the lysosomal lumen, measured by the concentration of the hydrogen ion.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-03-23T10:23:41Z					biological_process											owl:Class	
GO:0007040	biolink:NamedThing	lysosome organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lysosome. A lysosome is a cytoplasmic, membrane-bounded organelle that is found in most animal cells and that contains a variety of hydrolases.	tmpzr1t_l9r_go_relaxed.owl	lysosome organisation|lysosome organization and biogenesis													biological_process											owl:Class	
GO:0030899	biolink:NamedThing	calcium-dependent ATPase activity	Catalysis of the reaction: ATP + H2O = ADP + phosphate. This reaction requires the presence of calcium ion (Ca2+).	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0090319	biolink:NamedThing	positive regulation of chylomicron remodeling	Any process that increases the rate, frequency, or extent of chylomicron remodeling. Chylomicron remodeling is the acquisition, loss or modification of a protein or lipid within a chylomicron, including the hydrolysis of triglyceride by lipoprotein lipase and the subsequent loss of free fatty acid.	tmpzr1t_l9r_go_relaxed.owl								tb	2010-04-30T10:09:08Z					biological_process											owl:Class	
GO:0034371	biolink:NamedThing	chylomicron remodeling	The acquisition, loss or modification of a protein or lipid within a chylomicron, including the hydrolysis of triglyceride by lipoprotein lipase and the subsequent loss of free fatty acid.	tmpzr1t_l9r_go_relaxed.owl	chylomicron remnant formation													biological_process											owl:Class	
GO:0030082	biolink:NamedThing	B800-850 antenna complex	Protein-pigment complex that absorbs light at 800 and 850 nm; is peripherally associated to the bacterial reaction center; transfers excitation energy to the B875 antenna complex.	tmpzr1t_l9r_go_relaxed.owl	LH2 complex|light harvesting complex II													cellular_component											owl:Class	
GO:0030079	biolink:NamedThing	light-harvesting complex, peripheral complex	Bacteriochlorophyll a binding complex that is peripherally associated to the bacterial reaction center.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0035532	biolink:NamedThing	negative regulation of chemokine (C-C motif) ligand 6 production	Any process that stops, prevents, or reduces the frequency, rate, or extent of production of chemokine (C-C motif) ligand 6 (CCL6).	tmpzr1t_l9r_go_relaxed.owl	negative regulation of CCL6 production|negative regulation of chemokine (C-C motif) ligand 6 secretion							bf	2010-05-07T10:23:40Z			GO:0035536		biological_process											owl:Class	
GO:0035530	biolink:NamedThing	chemokine (C-C motif) ligand 6 production	The appearance of chemokine (C-C motif) ligand 6 (CCL6) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	tmpzr1t_l9r_go_relaxed.owl	CCL6 production							bf	2010-05-07T10:21:15Z					biological_process											owl:Class	
GO:0048567	biolink:NamedThing	ectodermal digestive tract morphogenesis	The process in which the anatomical structures of the ectodermal digestive tract are generated and organized. The ectodermal digestive tract includes those portions of the digestive tract that are derived from ectoderm.	tmpzr1t_l9r_go_relaxed.owl	ectodermal gut morphogenesis													biological_process											owl:Class	
GO:0032374	biolink:NamedThing	regulation of cholesterol transport	Any process that modulates the frequency, rate or extent of the directed movement of cholesterol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0140531	biolink:NamedThing	regulation of osmosensory signaling MAPK cascade	Any process that modulates the frequency, rate or extent of osmosensory signaling MAPK cascade.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/20162						pg	2020-10-20T15:38:10Z					biological_process											owl:Class	
GO:0000161	biolink:NamedThing	osmosensory signaling MAPK cascade	A series of molecular signals in which a stress-activated protein kinase (SAPK) cascade relays one or more of the signals, containing at least a Hog1/Sty1 family MAPK, a Pbs2/Wis1 family MAPKK and a Ssk2/Win1 family MAP3K.	tmpzr1t_l9r_go_relaxed.owl	activation of MAPKK activity involved in osmosensory signaling pathway|osmolarity sensing, activation of MAP kinase kinase kinase activity|activation of MAPK activity involved in osmosensory signaling pathway|activation of MAPKKK activity during osmolarity sensing|osmolarity sensing, activation of MAPKK activity|osmolarity sensing, activation of MAPKKK activity|osmolarity sensing, MAPKKK cascade|Hog1/Sty1 stress-activated MAPK cascade|activation of MAPKKK activity involved in osmosensory signaling pathway|High Osmolarity Glycerol (HOG) MAPK pathway|MAPKKK cascade involved in osmosensory signalling pathway|Hog1 MAPK pathway|inactivation of MAPK activity involved in osmosensory signaling pathway|osmolarity sensing, activation of MAP kinase kinase activity|termination of MAPK activity during osmolarity sensing|activation of MAPKK activity during osmolarity sensing|osmolarity sensing, activation of MAPK activity|MAPK cascade involved in osmosensory signaling pathway|activation of Pbs2 kinase|MAPKKK cascade involved in osmosensory signaling pathway|MAPKKK cascade during osmolarity sensing	https://github.com/geneontology/go-ontology/issues/20380										GO:0000169|GO:0000167|GO:0007233|GO:0000168|GO:0000173		biological_process											owl:Class	
GO:0072140	biolink:NamedThing	DCT cell development	The process whose specific outcome is the progression of a distal convoluted tubule cell over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl	distal convoluted tubule cell development							mah	2010-02-24T01:36:21Z					biological_process											owl:Class	
GO:0072069	biolink:NamedThing	DCT cell differentiation	The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the distal convoluted tubule cells of the kidney as it progresses from its formation to the mature state.	tmpzr1t_l9r_go_relaxed.owl	distal convoluted tubule cell differentiation							mah	2010-01-25T04:17:22Z					biological_process											owl:Class	
GO:0021578	biolink:NamedThing	hindbrain maturation	A developmental process, independent of morphogenetic (shape) change, that is required for the hindbrain to attain its fully functional state. The hindbrain is the region consisting of the medulla, pons and cerebellum. Areas of the hindbrain control motor and autonomic functions.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0021626	biolink:NamedThing	central nervous system maturation	A developmental process, independent of morphogenetic (shape) change, that is required for the central nervous system to attain its fully functional state. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain and spinal cord. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0031093	biolink:NamedThing	platelet alpha granule lumen	The volume enclosed by the membrane of the platelet alpha granule.	tmpzr1t_l9r_go_relaxed.owl	platelet alpha-granule lumen													cellular_component											owl:Class	
GO:0031091	biolink:NamedThing	platelet alpha granule	A secretory organelle found in blood platelets, which is unique in that it exhibits further compartmentalization and acquires its protein content via two distinct mechanisms: (1) biosynthesis predominantly at the megakaryocyte (MK) level (with some vestigial platelet synthesis) (e.g. platelet factor 4) and (2) endocytosis and pinocytosis at both the MK and circulating platelet levels (e.g. fibrinogen (Fg) and IgG).	tmpzr1t_l9r_go_relaxed.owl	platelet alpha-granule				Wikipedia:Platelet_alpha-granule									cellular_component											owl:Class	
GO:0034221	biolink:NamedThing	fungal-type cell wall chitin biosynthetic process	The chemical reactions and pathways resulting in the formation of cell wall chitin, a linear polysaccharide consisting of P-1,4-linked N-acetyl-D-glucosamine residues, found in the walls of fungal cells.	tmpzr1t_l9r_go_relaxed.owl	fungal-type cell wall chitin anabolism|fungal-type cell wall chitin synthesis|fungal-type cell wall chitin biosynthesis|fungal-type cell wall chitin formation													biological_process											owl:Class	
GO:0009272	biolink:NamedThing	fungal-type cell wall biogenesis	A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a fungal-type cell wall. The fungal-type cell wall contains beta-glucan and may contain chitin.	tmpzr1t_l9r_go_relaxed.owl	chitin- and beta-glucan-containing cell wall biogenesis|fungal-type cell wall formation|fungal-type cell wall synthesis|fungal-type cell wall biosynthetic process|fungal-type cell wall anabolism													biological_process											owl:Class	
GO:1903281	biolink:NamedThing	positive regulation of calcium:sodium antiporter activity	Any process that activates or increases the frequency, rate or extent of calcium:sodium antiporter activity.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of mitochondrial sodium/calcium ion exchange|up-regulation of calcium:sodium antiporter activity|upregulation of sodium:calcium exchange|up regulation of sodium:calcium exchange|upregulation of sodium/calcium exchanger|up-regulation of sodium/calcium exchanger|upregulation of mitochondrial sodium/calcium ion exchange|upregulation of calcium:sodium antiporter activity|activation of sodium:calcium exchange|activation of mitochondrial sodium/calcium ion exchange|up-regulation of mitochondrial sodium/calcium ion exchange|positive regulation of sodium/calcium exchanger|up regulation of sodium/calcium exchanger|up-regulation of sodium:calcium exchange|activation of sodium/calcium exchanger|up regulation of calcium:sodium antiporter activity|activation of calcium:sodium antiporter activity|positive regulation of sodium:calcium exchange|up regulation of mitochondrial sodium/calcium ion exchange							rl	2014-08-11T12:53:47Z					biological_process											owl:Class	
GO:0004901	biolink:NamedThing	granulocyte macrophage colony-stimulating factor receptor activity	Combining with granulocyte macrophage colony-stimulating factor (GM-CSF) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	CSF-2 receptor activity|CSF2R|granulocyte macrophage colony stimulating factor receptor activity|GMC-SF receptor activity|GM-CSF receptor activity											GO:0030525		molecular_function											owl:Class	
GO:0042021	biolink:NamedThing	granulocyte macrophage colony-stimulating factor complex binding	Binding to a granulocyte macrophage colony-stimulating factor complex.	tmpzr1t_l9r_go_relaxed.owl	GM-CSF complex binding|granulocyte macrophage colony stimulating factor complex binding|GMC-SF complex binding													molecular_function											owl:Class	
GO:0071712	biolink:NamedThing	ER-associated misfolded protein catabolic process	The chemical reactions and pathways resulting in the breakdown of misfolded proteins transported from the endoplasmic reticulum and targeted to cytoplasmic proteasomes for degradation.	tmpzr1t_l9r_go_relaxed.owl	endoplasmic reticulum-associated misfolded protein catabolic process|ER-associated misfolded protein breakdown|ER-associated misfolded protein degradation|endoplasmic reticulum-associated misfolded protein catabolism|proteasomal protein catabolism of misfolded ER proteins|ER-associated misfolded protein catabolism					See also the biological process terms 'unfolded protein response ; GO:0030968' and 'retrograde protein transport, ER to cytosol ; GO:0030970'.		mah	2010-03-10T12:53:27Z					biological_process											owl:Class	
GO:0035053	biolink:NamedThing	dorsal vessel heart proper cell fate commitment	The commitment of dorsal vessel cardioblast cells to a heart proper cell fate and their capacity to differentiate into heart cells. An example of this process is found in Drosophila melanogaster.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0035054	biolink:NamedThing	embryonic heart tube anterior/posterior pattern specification	The establishment, maintenance and elaboration of cell differentiation that results in the anterior/posterior subdivision of the embryonic heart tube. In Drosophila this results in subdivision of the dorsal vessel into to the posterior heart proper and the anterior aorta.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0033276	biolink:NamedThing	transcription factor TFTC complex	A protein complex that does not contain either a TATA-binding protein (TBP) or a TBP-like factor, but is composed of several TAFIIs and other proteins, including a histone acetyltransferase. This complex is able to nucleate transcription initiation by RNA polymerase II, can mediate transcriptional activation, and has histone acetyltransferase activity.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0016591	biolink:NamedThing	RNA polymerase II, holoenzyme	A nuclear DNA-directed RNA polymerase complex containing an RNA polymerase II core enzyme as well as additional proteins and transcription factor complexes, that are capable of promoter recognition and transcription initiation from an RNA polymerase II promoter in vivo. These additional components may include general transcription factor complexes TFIIA, TFIID, TFIIE, TFIIF, or TFIIH, as well as Mediator, SWI/SNF, GCN5, or SRBs and confer the ability to recognize promoters.	tmpzr1t_l9r_go_relaxed.owl	DNA-directed RNA polymerase II, holoenzyme													cellular_component											owl:Class	
GO:2001086	biolink:NamedThing	laminarabiose transport	The directed movement of a laminarabioseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl								jl	2011-09-21T12:55:01Z					biological_process											owl:Class	
GO:0001763	biolink:NamedThing	morphogenesis of a branching structure	The process in which the anatomical structures of branches are generated and organized. A branch is a division or offshoot from a main stem. Examples in animals would include blood vessels, nerves, lymphatics and other endothelial or epithelial tubes.	tmpzr1t_l9r_go_relaxed.owl	branching morphogenesis													biological_process											owl:Class	
GO:1904247	biolink:NamedThing	positive regulation of polynucleotide adenylyltransferase activity	Any process that activates or increases the frequency, rate or extent of polynucleotide adenylyltransferase activity.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of polyadenylic polymerase activity|activation of ATP-polynucleotide adenylyltransferase activity|activation of ATP:polynucleotidylexotransferase activity|activation of polyadenylic polymerase activity|activation of poly(A) hydrolase activity|activation of polynucleotide adenylyltransferase activity|positive regulation of polyadenylate nucleotidyltransferase activity|up-regulation of poly-A polymerase activity|up-regulation of polyadenylic polymerase activity|up regulation of adenosine triphosphate:ribonucleic acid adenylyltransferase activity|up-regulation of AMP polynucleotidylexotransferase activity|activation of poly-A polymerase activity|up regulation of ATP:polynucleotide adenylyltransferase activity|up regulation of polyadenylate synthetase activity|upregulation of ATP:polynucleotidylexotransferase activity|up-regulation of polyadenylate synthetase activity|upregulation of AMP polynucleotidylexotransferase activity|up-regulation of NTP polymerase activity|upregulation of polyadenylic acid polymerase activity|positive regulation of NTP polymerase activity|up-regulation of polynucleotide adenylyltransferase activity|activation of NTP polymerase activity|up regulation of NTP polymerase activity|positive regulation of poly(A) synthetase activity|up-regulation of poly(A) synthetase activity|up regulation of ATP:polynucleotidylexotransferase activity|up regulation of terminal riboadenylate transferase activity|activation of polyadenylate polymerase activity|up-regulation of poly(A) polymerase activity|up-regulation of ATP:polynucleotidylexotransferase activity|positive regulation of poly-A polymerase activity|activation of AMP polynucleotidylexotransferase activity|activation of RNA formation factors, PF1|activation of RNA adenylating enzyme activity|up regulation of RNA adenylating enzyme activity|activation of polyadenylate nucleotidyltransferase activity|upregulation of polynucleotide adenylyltransferase activity|upregulation of ATP-polynucleotide adenylyltransferase activity|upregulation of polyadenylate synthetase activity|upregulation of poly(A) hydrolase activity|up regulation of poly(A) synthetase activity|up-regulation of RNA adenylating enzyme activity|upregulation of polyadenylate nucleotidyltransferase activity|activation of poly(A) polymerase activity|activation of adenosine triphosphate:ribonucleic acid adenylyltransferase activity|activation of terminal riboadenylate transferase activity|up-regulation of terminal riboadenylate transferase activity|up-regulation of ATP-polynucleotide adenylyltransferase activity|up-regulation of polyadenylic acid polymerase activity|up-regulation of polyadenylate nucleotidyltransferase activity|upregulation of polyadenylate polymerase activity|positive regulation of poly(A) polymerase activity|upregulation of terminal riboadenylate transferase activity|up regulation of RNA formation factors, PF1|activation of poly(A) synthetase activity|activation of polyadenylic acid polymerase activity|upregulation of poly-A polymerase activity|upregulation of polyadenylic polymerase activity|positive regulation of ATP:polynucleotide adenylyltransferase activity|upregulation of adenosine triphosphate:ribonucleic acid adenylyltransferase activity|up-regulation of polyadenylate polymerase activity|up regulation of polyadenylate nucleotidyltransferase activity|up regulation of ATP-polynucleotide adenylyltransferase activity|up-regulation of adenosine triphosphate:ribonucleic acid adenylyltransferase activity|up-regulation of RNA formation factors, PF1|up regulation of poly(A) polymerase activity|positive regulation of polyadenylate synthetase activity|activation of ATP:polynucleotide adenylyltransferase activity|up regulation of AMP polynucleotidylexotransferase activity|positive regulation of terminal riboadenylate transferase activity|upregulation of NTP polymerase activity|positive regulation of adenosine triphosphate:ribonucleic acid adenylyltransferase activity|upregulation of poly(A) polymerase activity|upregulation of RNA adenylating enzyme activity|positive regulation of polyadenylate polymerase activity|upregulation of poly(A) synthetase activity|positive regulation of polyadenylic acid polymerase activity|positive regulation of RNA adenylating enzyme activity|positive regulation of ATP-polynucleotide adenylyltransferase activity|positive regulation of RNA formation factors, PF1|upregulation of RNA formation factors, PF1|up regulation of polyadenylate polymerase activity|positive regulation of AMP polynucleotidylexotransferase activity|up regulation of poly(A) hydrolase activity|positive regulation of ATP:polynucleotidylexotransferase activity|activation of polyadenylate synthetase activity|positive regulation of poly(A) hydrolase activity|up-regulation of poly(A) hydrolase activity|up regulation of polyadenylic acid polymerase activity|upregulation of ATP:polynucleotide adenylyltransferase activity|up-regulation of ATP:polynucleotide adenylyltransferase activity|up regulation of poly-A polymerase activity|up regulation of polynucleotide adenylyltransferase activity|up regulation of polyadenylic polymerase activity							kmv	2015-05-19T14:47:32Z					biological_process											owl:Class	
GO:0004652	biolink:NamedThing	polynucleotide adenylyltransferase activity	Catalysis of the template-independent extension of the 3'- end of an RNA or DNA strand by addition of one adenosine molecule at a time. Cannot initiate a chain 'de novo'. The primer, depending on the source of the enzyme, may be an RNA or DNA fragment, or oligo(A) bearing a 3'-OH terminal group.	tmpzr1t_l9r_go_relaxed.owl	ATP:polynucleotide adenylyltransferase activity|AMP polynucleotidylexotransferase activity|polyadenylic polymerase activity|poly(A) synthetase activity|terminal riboadenylate transferase activity|poly(A) polymerase activity|RNA formation factors, PF1|polyadenylic acid polymerase activity|polyadenylate synthetase activity|ATP-polynucleotide adenylyltransferase activity|ATP:polynucleotidylexotransferase activity|poly(A) hydrolase activity|adenosine triphosphate:ribonucleic acid adenylyltransferase activity|poly-A polymerase activity|RNA adenylating enzyme activity|polyadenylate polymerase activity|NTP polymerase activity|polyadenylate nucleotidyltransferase activity				EC:2.7.7.19|RHEA:11332|Reactome:R-HSA-72185|MetaCyc:POLYNUCLEOTIDE-ADENYLYLTRANSFERASE-RXN									molecular_function											owl:Class	
GO:0016198	biolink:NamedThing	axon choice point recognition	The recognition of molecules at a choice point by an axon growth cone; at a choice point the growth cone determines the direction of its future growth.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0008900	biolink:NamedThing	P-type potassium:proton transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + H+(in) + K+(out) = ADP + phosphate + H+(out) + K+(in).	tmpzr1t_l9r_go_relaxed.owl	hydrogen:potassium-exchanging ATPase activity|H+-K+-ATPase activity|H(+)/K(+)-exchanging ATPase activity|H,K-ATPase activity|proton pump activity|hydrogen:potassium exchanging ATPase activity|gastric H(+)/K(+) ATPase activity|H+/K+-ATPase activity|potassium:proton exchanging ATPase activity|gastric H+/K+ ATPase|ATP phosphohydrolase (H+/K+-exchanging)|H(+)/K(+)-ATPase activity|hydrogen/potassium-exchanging ATPase activity|H+/K+-exchanging ATPase activity|(K+ + H+)-ATPase activity	https://github.com/geneontology/go-ontology/issues/20821			Reactome:R-HSA-937311|EC:7.2.2.19|RHEA:22044							GO:0005390		molecular_function											owl:Class	
GO:0033633	biolink:NamedThing	negative regulation of cell-cell adhesion mediated by integrin	Any process that stops, prevents, or reduces the frequency, rate, or extent of cell-cell adhesion mediated by integrin.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of cell-cell adhesion mediated by integrin complex													biological_process											owl:Class	
GO:0044343	biolink:NamedThing	canonical Wnt signaling pathway involved in regulation of type B pancreatic cell proliferation	The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes that modulates the rate or frequency of pancreatic B cell proliferation. Pancreatic B cell are cells of the pancreas that secrete insulin.	tmpzr1t_l9r_go_relaxed.owl	canonical Wnt receptor signalling pathway involved in regulation of type B pancreatic cell proliferation|canonical Wnt receptor signalling pathway involved in regulation of pancreatic B cell proliferation|canonical Wnt receptor signaling pathway involved in regulation of type B pancreatic cell proliferation|canonical Wnt receptor signaling pathway involved in regulation of pancreatic B cell proliferation|canonical Wnt-activated signaling pathway involved in regulation of type B pancreatic cell proliferation|canonical Wnt receptor signaling pathway involved in pancreatic beta cell proliferation							jl	2010-08-25T01:53:22Z					biological_process											owl:Class	
GO:0061469	biolink:NamedThing	regulation of type B pancreatic cell proliferation	Any process that modulates the frequency, rate or extent of type B pancreatic cell proliferation.	tmpzr1t_l9r_go_relaxed.owl								dph	2012-11-01T13:16:23Z					biological_process											owl:Class	
GO:0004743	biolink:NamedThing	pyruvate kinase activity	Catalysis of the reaction: = ADP + H(+) + phosphoenolpyruvate => ATP + pyruvate.	tmpzr1t_l9r_go_relaxed.owl	ATP:pyruvate 2-O-phosphotransferase activity|phosphoenol transphosphorylase activity|phosphoenolpyruvate kinase activity				RHEA:18159|EC:2.7.1.40|MetaCyc:PEPDEPHOS-RXN|Reactome:R-HSA-71670									molecular_function											owl:Class	
GO:0071539	biolink:NamedThing	protein localization to centrosome	A process in which a protein is transported to, or maintained at, the centrosome.	tmpzr1t_l9r_go_relaxed.owl	protein localisation to centrosome							mah	2010-01-12T02:09:45Z					biological_process											owl:Class	
GO:0044663	biolink:NamedThing	establishment or maintenance of cell type involved in phenotypic switching	A cellular process of the specification, formation or maintenance of an alternative cell type, occurring as part of the process of phenotypic switching. Phenotypic switching begins with changes in cell morphology and altered gene expression patterns and ends when the morphology of a population of cells has reverted back to the default state, accompanied by altered expression patterns.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-08-07T14:30:07Z					biological_process											owl:Class	
GO:0036166	biolink:NamedThing	phenotypic switching	A reversible switch of a cell from one cell type or form to another, at a frequency above the expected frequency for somatic mutations. Phenotypic switching involves changes in cell morphology and altered gene expression patterns. For example, Candida albicans switches from white cells to opaque cells for sexual mating. Phenotypic switching also occurs in multicellular organisms; smooth muscle cells (SMCs) exhibit phenotypic transitions to allow rapid adaption to fluctuating environmental cues.	tmpzr1t_l9r_go_relaxed.owl	phenotypic dimorphism					Mating type switching is not considered a type of phenotypic switching: for mating type switching, consider instead annotating to 'mating type switching ; GO:0007533'.		bf	2012-03-27T01:31:28Z					biological_process											owl:Class	
GO:1905629	biolink:NamedThing	positive regulation of serotonin biosynthetic process	Any process that activates or increases the frequency, rate or extent of serotonin biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	up regulation of serotonin synthesis|upregulation of serotonin biosynthesis|upregulation of serotonin formation|upregulation of serotonin anabolism|up-regulation of serotonin biosynthetic process|positive regulation of serotonin anabolism|activation of serotonin formation|up regulation of serotonin biosynthetic process|positive regulation of serotonin biosynthesis|activation of serotonin synthesis|positive regulation of serotonin synthesis|up-regulation of serotonin biosynthesis|upregulation of serotonin synthesis|up regulation of serotonin formation|up regulation of serotonin anabolism|up-regulation of serotonin formation|up-regulation of serotonin anabolism|activation of serotonin biosynthesis|positive regulation of serotonin formation|up regulation of serotonin biosynthesis|up-regulation of serotonin synthesis|activation of serotonin anabolism|activation of serotonin biosynthetic process|upregulation of serotonin biosynthetic process							pad	2016-10-31T14:26:36Z					biological_process											owl:Class	
GO:0042427	biolink:NamedThing	serotonin biosynthetic process	The chemical reactions and pathways resulting in the formation of serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties.	tmpzr1t_l9r_go_relaxed.owl	serotonin formation|serotonin biosynthesis|serotonin synthesis|serotonin anabolism				Wikipedia:Serotonin									biological_process											owl:Class	
GO:1900563	biolink:NamedThing	dehydroaustinol biosynthetic process	The chemical reactions and pathways resulting in the formation of dehydroaustinol.	tmpzr1t_l9r_go_relaxed.owl	dehydroaustinol formation|dehydroaustinol synthesis|dehydroaustinol biosynthesis|dehydroaustinol anabolism							di	2012-05-15T06:28:03Z					biological_process											owl:Class	
GO:0039692	biolink:NamedThing	single stranded viral RNA replication via double stranded DNA intermediate	A viral genome replication where the template is single-stranded RNA (ssRNA), and which proceeds via a double stranded DNA (dsDNA) intermediate molecule. Viral genomic RNA is first reverse transcribed into dsDNA, which integrates into the host chromosomal DNA, where it is transcribed by host RNA polymerase II.	tmpzr1t_l9r_go_relaxed.owl	retroviral genome replication|viral ssRNA replication via dsDNA intermediate				VZ:1937			bf	2013-10-17T15:59:43Z			GO:0045090		biological_process											owl:Class	
GO:0048069	biolink:NamedThing	eye pigmentation	Establishment of a pattern of pigment in the eye of an organism.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Eye_color									biological_process											owl:Class	
GO:1903347	biolink:NamedThing	negative regulation of bicellular tight junction assembly	Any process that stops, prevents or reduces the frequency, rate or extent of tight junction assembly.	tmpzr1t_l9r_go_relaxed.owl	down regulation of tight junction formation|down regulation of tight junction assembly|down-regulation of tight junction formation|inhibition of tight junction formation|downregulation of tight junction formation|down-regulation of tight junction assembly|negative regulation of tight junction formation|inhibition of tight junction assembly|downregulation of tight junction assembly							pr	2014-08-19T11:02:14Z					biological_process											owl:Class	
GO:0070830	biolink:NamedThing	bicellular tight junction assembly	The aggregation, arrangement and bonding together of a set of components to form a tight junction, an occluding cell-cell junction that is composed of a branching network of sealing strands that completely encircles the apical end of each cell in an epithelial sheet.	tmpzr1t_l9r_go_relaxed.owl	tight junction formation							mah	2009-07-23T04:32:38Z					biological_process											owl:Class	
GO:0005754	biolink:NamedThing	mitochondrial proton-transporting ATP synthase, catalytic core	The hexamer, comprising three alpha and three beta subunits, that possesses the catalytic activity of the mitochondrial hydrogen-transporting ATP synthase.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:2000312	biolink:NamedThing	regulation of kainate selective glutamate receptor activity	Any process that modulates the frequency, rate or extent of kainate selective glutamate receptor activity.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-01-18T10:14:16Z					biological_process											owl:Class	
GO:2000028	biolink:NamedThing	regulation of photoperiodism, flowering	Any process that modulates the frequency, rate or extent of photoperiodism, flowering.	tmpzr1t_l9r_go_relaxed.owl	regulation of photoperiodic control of inflorescence development|regulation of response to night length, flowering|regulation of photoperiodic control of flowering time|regulation of response to day length, flowering|regulation of response to photoperiod, flowering							tb	2010-08-05T11:27:18Z					biological_process											owl:Class	
GO:0098834	biolink:NamedThing	presynaptic endocytic zone cytoplasmic component	The cytoplasmic component of the presynaptic endocytic zone.	tmpzr1t_l9r_go_relaxed.owl	cortex of presynaptic endocytic zone													cellular_component											owl:Class	
GO:0098833	biolink:NamedThing	presynaptic endocytic zone	A specialized region of the plasma membrane and underlying cytoplasm which surround the the active zone, into which synaptic vesicle membranes are recycled following exocytosis.  It is especially enriched in endocytic proteins following intense activity.	tmpzr1t_l9r_go_relaxed.owl						May be identical to periactive zone?								cellular_component											owl:Class	
GO:0030252	biolink:NamedThing	growth hormone secretion	The regulated release of growth hormone from secretory granules into the blood.	tmpzr1t_l9r_go_relaxed.owl	somatotropin secretion													biological_process											owl:Class	
GO:0000212	biolink:NamedThing	meiotic spindle organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the microtubule spindle during a meiotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl	meiotic spindle organization and biogenesis|spindle organization during meiosis|meiotic spindle organisation|meiotic spindle stabilization											GO:0043147		biological_process											owl:Class	
GO:1905588	biolink:NamedThing	plant-type cell wall modification involved in stomatal movement	Any plant-type cell wall modification that is involved in stomatal movement.	tmpzr1t_l9r_go_relaxed.owl	cellulose and pectin-containing cell wall modification involved in stomatal movement							lr	2016-10-25T00:29:26Z					biological_process											owl:Class	
GO:0010118	biolink:NamedThing	stomatal movement	The process of opening or closing of stomata, which is directly related to the stomatal conductance (measuring rate of passage of either water vapor or carbon dioxide (CO2) through stomata).	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1902004	biolink:NamedThing	positive regulation of amyloid-beta formation	Any process that activates or increases the frequency, rate or extent of amyloid-beta formation.	tmpzr1t_l9r_go_relaxed.owl	activation of beta-amyloid formation|up regulation of beta-amyloid formation|upregulation of beta-amyloid formation|up-regulation of beta-amyloid formation|positive regulation of beta-amyloid formation							dph	2013-03-21T19:59:31Z					biological_process											owl:Class	
GO:0034205	biolink:NamedThing	amyloid-beta formation	The generation of amyloid-beta by cleavage of the amyloid precursor protein (APP).	tmpzr1t_l9r_go_relaxed.owl	beta-amyloid polypeptide formation from amyloid precursor protein|beta-amyloid formation|beta-amyloid polypeptide formation from APP					Note that this term does not fall under the general GO definition for biosynthetic processes, which is 'The chemical reactions and pathways resulting in the formation of... ', because amyloid-beta can only be formed by the proteolysis of a larger molecule (see term definition). The word 'formation' is therefore used in place of biosynthesis. Also, note that this term refers to the production of the amyloid-beta polypeptide from the amyloid precursor protein (APP), and should be used to annotate e.g. secretases that cleave APP to form amyloid-beta. To annotate gene products involved in the formation of amyloid fibrils, please consider 'amyloid fibril formation' (GO:1990000).								biological_process											owl:Class	
GO:0061558	biolink:NamedThing	cranial ganglion maturation	A developmental process, independent of morphogenetic (shape) change, that is required for a cranial ganglion to attain its fully functional state.	tmpzr1t_l9r_go_relaxed.owl	cranial ganglia maturation							dph	2013-07-10T08:59:52Z					biological_process											owl:Class	
GO:0061550	biolink:NamedThing	cranial ganglion development	The process whose specific outcome is the progression of a cranial ganglion over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl	cranial ganglia development							dph	2013-07-10T08:40:14Z					biological_process											owl:Class	
GO:0072187	biolink:NamedThing	metanephric cap formation	The developmental process pertaining to the initial formation of a metanephric cap from unspecified parts. The metanephric cap is formed by the condensation of metanephric mesenchymal cells surrounding the ureteric bud tip.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-03-01T01:26:53Z					biological_process											owl:Class	
GO:0072186	biolink:NamedThing	metanephric cap morphogenesis	The process in which the anatomical structures of the metanephric cap are generated and organized. The metanephric cap is formed by the condensation of metanephric mesenchymal cells surrounding the ureteric bud tip.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-03-01T01:22:51Z					biological_process											owl:Class	
GO:0010726	biolink:NamedThing	positive regulation of hydrogen peroxide metabolic process	Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving hydrogen peroxide.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of hydrogen peroxide metabolism													biological_process											owl:Class	
GO:0042743	biolink:NamedThing	hydrogen peroxide metabolic process	The chemical reactions and pathways involving hydrogen peroxide (H2O2), a potentially harmful byproduct of aerobic cellular respiration which can cause damage to DNA.	tmpzr1t_l9r_go_relaxed.owl	H2O2 metabolic process|hydrogen peroxide metabolism													biological_process											owl:Class	
GO:1902856	biolink:NamedThing	negative regulation of non-motile cilium assembly	Any process that stops, prevents or reduces the frequency, rate or extent of non-motile cilium assembly.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of nonmotile primary cilium assembly|downregulation of nonmotile primary cilia assembly|downregulation of sensory cilium assembly|negative regulation of nonmotile primary cilia assembly|down-regulation of nonmotile primary cilia assembly|negative regulation of immotile primary cilium assembly|down-regulation of sensory cilium biogenesis|down regulation of nonmotile primary cilium assembly|downregulation of nonmotile primary cilium assembly|down-regulation of immotile primary cilium assembly|inhibition of nonmotile primary cilium assembly|inhibition of immotile primary cilium assembly|inhibition of nonmotile primary cilia assembly|inhibition of sensory cilium biogenesis|down regulation of sensory cilium biogenesis|inhibition of sensory cilium assembly|negative regulation of sensory cilium assembly|negative regulation of sensory cilium biogenesis|down regulation of immotile primary cilium assembly|downregulation of immotile primary cilium assembly|down-regulation of nonmotile primary cilium assembly|downregulation of sensory cilium biogenesis|down regulation of nonmotile primary cilia assembly|down regulation of sensory cilium assembly|down-regulation of sensory cilium assembly							kmv	2014-04-02T15:42:17Z					biological_process											owl:Class	
GO:1905515	biolink:NamedThing	non-motile cilium assembly	The aggregation, arrangement and bonding together of a set of components to form a non-motile cilium.	tmpzr1t_l9r_go_relaxed.owl	nonmotile primary cilium assembly|sensory cilium biogenesis|non-motile cilium formation|nonmotile cilium formation|nonmotile cilium assembly|nonmotile primary cilia assembly|immotile primary cilium assembly|sensory cilium assembly							pr	2016-09-30T11:55:15Z			GO:0035058		biological_process											owl:Class	
GO:0052074	biolink:NamedThing	positive regulation by symbiont of host salicylic acid-mediated defense response	Any process in which a symbiont activates, maintains or increases the frequency, rate or extent of the salicylic acid-mediated defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	activation by symbiont of host salicylic acid-mediated defense response|induction by organism of host salicylic acid-mediated defense response|positive regulation by organism of host SA-mediated defense response|up regulation by symbiont of host salicylic acid-mediated defense response|up-regulation by symbiont of host salicylic acid-mediated defense response|induction by organism of host SA-mediated defense response|upregulation by symbiont of host salicylic acid-mediated defense response|positive regulation by organism of salicylic acid-mediated defense response of other organism involved in symbiotic interaction|stimulation by symbiont of host salicylic acid-mediated defense response											GO:0052272		biological_process											owl:Class	
GO:0021662	biolink:NamedThing	rhombomere 4 structural organization	The process that contributes to creating the structural organization of rhombomere 4. This process pertains to the physical shaping of a rudimentary structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.	tmpzr1t_l9r_go_relaxed.owl	rhombomere 4 structural organisation													biological_process											owl:Class	
GO:0021661	biolink:NamedThing	rhombomere 4 morphogenesis	The process in which the anatomical structure of rhombomere 4 is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0014726	biolink:NamedThing	negative regulation of extraocular skeletal muscle development	Any process that stops, prevents, or reduces the frequency, rate or extent of extraocular skeletal muscle development. Extraocular skeletal muscle development is the process whose specific outcome is the progression of the extraocular skeletal muscle over time, from its formation to the mature structure. The extraocular muscle is derived from cranial mesoderm and controls eye movements. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0002074	biolink:NamedThing	extraocular skeletal muscle development	The process whose specific outcome is the progression of the extraocular skeletal muscle over time, from its formation to the mature structure. The extraocular muscle is derived from cranial mesoderm and controls eye movements. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle. An example of this process is found in Mus musculus.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0031630	biolink:NamedThing	regulation of synaptic vesicle fusion to presynaptic active zone membrane	Any process that modulates the frequency, rate or extent of synaptic vesicle fusion to the presynaptic membrane.	tmpzr1t_l9r_go_relaxed.owl	regulation of synaptic vesicle fusion to presynaptic membrane|regulation of synaptic vesicle fusion to pre-synaptic membrane													biological_process											owl:Class	
GO:0031629	biolink:NamedThing	synaptic vesicle fusion to presynaptic active zone membrane	Fusion of the membrane of a synaptic vesicle with the presynaptic active zone membrane, thereby releasing its cargo neurotransmitters into the synaptic cleft.	tmpzr1t_l9r_go_relaxed.owl	synaptic vesicle fusion|synaptic vesicle fusion to pre-synaptic membrane|synaptic vesicle fusion to presynaptic membrane													biological_process											owl:Class	
GO:0009883	biolink:NamedThing	red or far-red light photoreceptor activity	The function of absorbing and responding to electromagnetic radiation with a wavelength of approximately 660-730nm. The response may involve a change in conformation.	tmpzr1t_l9r_go_relaxed.owl	red/far-red light photoreceptor activity													molecular_function											owl:Class	
GO:1902974	biolink:NamedThing	meiotic DNA replication initiation	Any DNA replication initiation involved in meiotic cell cycle DNA replication.	tmpzr1t_l9r_go_relaxed.owl	DNA replication initiation involved in meiotic cell cycle DNA replication|premeiotic DNA replication initiation|DNA replication initiation involved in meiotic DNA replication|initiation of premeiotic DNA synthesis|initiation of premeiotic DNA replication|initiation of meiotic DNA synthesis							jl	2014-05-06T15:21:06Z			GO:0072691		biological_process											owl:Class	
GO:1903985	biolink:NamedThing	regulation of intestinal D-glucose absorption	Any process that modulates the frequency, rate or extent of intestinal D-glucose absorption.	tmpzr1t_l9r_go_relaxed.owl								als	2015-03-04T10:07:55Z					biological_process											owl:Class	
GO:0001951	biolink:NamedThing	intestinal D-glucose absorption	Uptake of D-glucose into the blood by absorption from the small intestine.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0002022	biolink:NamedThing	detection of dietary excess	The neurological process in which the brain senses excessive caloric intake.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0002021	biolink:NamedThing	response to dietary excess	The physiological process in which dietary excess is sensed by the central nervous system, resulting in a reduction in food intake and increased energy expenditure.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0120271	biolink:NamedThing	negative regulation of nuclear-transcribed mRNA catabolic process, meiosis-specific transcripts	Any process that stops, prevents or reduces the frequency, rate or extent of selective degradation of meiosis-specific nuclear transcribed transcripts during vegetative growth, by a mechanism that requires determinant of selective removal (DSR) sequences in the targeted mRNAs and involves a YTH family protein.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/18757						krc	2020-10-08T21:01:06Z					biological_process											owl:Class	
GO:0035990	biolink:NamedThing	tendon cell differentiation	The process in which a relatively unspecialized cell acquires the specialized features of a tendon cell. Tendon cell are elongated fibrocytes in which the cytoplasm is stretched between the collagen fibres of the tendon. Tendon cells have a central cell nucleus with a prominent nucleolus, a well-developed rough endoplasmic reticulum, and are responsible for synthesis and turnover of tendon fibres and ground substance.	tmpzr1t_l9r_go_relaxed.owl	tenocyte differentiation|muscle attachment cell differentiation							bf	2011-08-26T04:16:06Z					biological_process											owl:Class	
GO:0061218	biolink:NamedThing	negative regulation of mesonephros development	Any process that decreases the rate, frequency or extent of mesonephros development. Mesonephros development is the process whose specific outcome is the progression of the mesonephros over time, from its formation to the mature structure. The mesonephros is an organ that filters the blood and excretes the end products of body metabolism in the form of urine.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-08-17T03:43:06Z					biological_process											owl:Class	
GO:0004103	biolink:NamedThing	choline kinase activity	Catalysis of the reaction: ATP + choline = ADP + choline phosphate + 2 H(+).	tmpzr1t_l9r_go_relaxed.owl	choline kinase (phosphorylating)|choline-ethanolamine kinase activity|choline phosphokinase activity|ATP:choline phosphotransferase activity				EC:2.7.1.32|RHEA:12837|MetaCyc:CHOLINE-KINASE-RXN|KEGG_REACTION:R01021|Reactome:R-HSA-1483004									molecular_function											owl:Class	
GO:0006657	biolink:NamedThing	CDP-choline pathway	The phosphatidylcholine biosynthetic process that begins with the phosphorylation of choline and ends with the combination of CDP-choline with diacylglycerol to form phosphatidylcholine.	tmpzr1t_l9r_go_relaxed.owl	Kennedy pathway|phosphatidylcholine biosynthesis from choline				MetaCyc:PWY3O-450									biological_process											owl:Class	
GO:0042276	biolink:NamedThing	error-prone translesion synthesis	The conversion of DNA-damage induced single-stranded gaps into large molecular weight DNA after replication by using a specialized DNA polymerase or replication complex to insert a defined nucleotide across the lesion. This process does not remove the replication-blocking lesions and causes an increase in the endogenous mutation level. For example, in E. coli, a low fidelity DNA polymerase, pol V, copies lesions that block replication fork progress. This produces mutations specifically targeted to DNA template damage sites, but it can also produce mutations at undamaged sites.	tmpzr1t_l9r_go_relaxed.owl	mutagenic PRR|error-prone postreplication DNA repair|mutagenic postreplication DNA repair													biological_process											owl:Class	
GO:0030673	biolink:NamedThing	axolemma	The portion of the plasma membrane surrounding an axon; it is a specialized trilaminar random mosaic of protein molecules floating within a fluid matrix of highly mobile phospholipid molecules, 7-8 nm in thickness.	tmpzr1t_l9r_go_relaxed.owl	axonal membrane				Wikipedia:Axolemma|NIF_Subcellular:sao250772229									cellular_component											owl:Class	
GO:0044304	biolink:NamedThing	main axon	The main axonal trunk, as opposed to the collaterals; i.e., excluding collaterals, terminal, spines, or dendrites.	tmpzr1t_l9r_go_relaxed.owl	axon shaft|axon trunk|axonal shaft				NIF_Subcellular:sao1596975044			jl	2010-02-05T03:48:17Z					cellular_component											owl:Class	
GO:0032716	biolink:NamedThing	negative regulation of interleukin-7 production	Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-7 production.	tmpzr1t_l9r_go_relaxed.owl	inhibition of interleukin-7 production|negative regulation of interleukin-7 secretion|negative regulation of IL-7 production|downregulation of interleukin-7 production|down-regulation of interleukin-7 production|down regulation of interleukin-7 production|negative regulation of interleukin-7 biosynthetic process											GO:0045412|GO:0150113		biological_process											owl:Class	
GO:0032636	biolink:NamedThing	interleukin-7 production	The appearance of interleukin-7 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	tmpzr1t_l9r_go_relaxed.owl	interleukin-7 secretion|interleukin-7 biosynthetic process|IL-7 production											GO:0072605|GO:0042227		biological_process											owl:Class	
GO:0048296	biolink:NamedThing	regulation of isotype switching to IgA isotypes	Any process that modulates the frequency, rate or extent of isotype switching to IgA isotypes.	tmpzr1t_l9r_go_relaxed.owl	regulation of isotype switch recombination to IgA isotypes|regulation of class switch recombination to IgA isotypes|regulation of class switching to IgA isotypes													biological_process											owl:Class	
GO:0048290	biolink:NamedThing	isotype switching to IgA isotypes	The switching of activated B cells from IgM biosynthesis to biosynthesis of an IgA isotype, accomplished through a recombination process involving an intrachromosomal deletion between switch regions that reside 5' of the IgM and one of the IgA constant region gene segments in the immunoglobulin heavy chain locus.	tmpzr1t_l9r_go_relaxed.owl	class switching to IgA isotypes|isotype switch recombination to IgA isotypes													biological_process											owl:Class	
GO:0060611	biolink:NamedThing	mammary gland fat development	The progression of the mammary gland fat over time, from its formation to the mature structure. The mammary fat is an adipose structure in the gland that is invaded by the mammary ducts.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-05-15T12:27:57Z					biological_process											owl:Class	
GO:0030879	biolink:NamedThing	mammary gland development	The process whose specific outcome is the progression of the mammary gland over time, from its formation to the mature structure. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk. Its development starts with the formation of the mammary line and ends as the mature gland cycles between nursing and weaning stages.	tmpzr1t_l9r_go_relaxed.owl	mammogenesis													biological_process											owl:Class	
GO:0032967	biolink:NamedThing	positive regulation of collagen biosynthetic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of collagen formation|positive regulation of collagen synthesis|positive regulation of collagen biosynthesis|positive regulation of collagen anabolism													biological_process											owl:Class	
GO:0021987	biolink:NamedThing	cerebral cortex development	The progression of the cerebral cortex over time from its initial formation until its mature state. The cerebral cortex is the outer layered region of the telencephalon.	tmpzr1t_l9r_go_relaxed.owl	corticogenesis|neocortex development													biological_process											owl:Class	
GO:0021543	biolink:NamedThing	pallium development	The process whose specific outcome is the progression of the pallium over time, from its formation to the mature structure. The pallium is the roof region of the telencephalon.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0004373	biolink:NamedThing	glycogen (starch) synthase activity	Catalysis of the reaction: UDP-glucose + (1,4)-alpha-D-glucosyl(n) = UDP + (1,4)-alpha-D-glucosyl(n+1).	tmpzr1t_l9r_go_relaxed.owl	UDPglucose:glycogen 4-alpha-D-glucosyltransferase activity|uridine diphosphoglucose-glycogen glucosyltransferase activity|UDPG-glycogen transglucosylase activity|glycogen (starch) synthetase activity|UDP-glucose:glycogen 4-alpha-D-glucosyltransferase activity|UDP-glucose-glycogen glucosyltransferase activity|UDP-glycogen synthase activity|UDPG-glycogen synthetase activity				EC:2.4.1.11|RHEA:18549|MetaCyc:2.4.1.11-RXN|Reactome:R-HSA-3322009|Reactome:R-HSA-3322001|Reactome:R-HSA-3322041|Reactome:R-HSA-3828061|Reactome:R-HSA-3858506									molecular_function											owl:Class	
GO:1903094	biolink:NamedThing	negative regulation of protein K48-linked deubiquitination	Any process that stops, prevents or reduces the frequency, rate or extent of protein K48-linked deubiquitination.	tmpzr1t_l9r_go_relaxed.owl	inhibition of protein K48-linked deubiquitination|down-regulation of protein K48-linked deubiquitination|downregulation of protein K48-linked deubiquitination|down regulation of protein K48-linked deubiquitination							bf	2014-06-03T12:27:54Z					biological_process											owl:Class	
GO:0071108	biolink:NamedThing	protein K48-linked deubiquitination	A protein deubiquitination process in which a K48-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 48 of the ubiquitin monomers, is removed from a protein.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-11-12T01:34:01Z					biological_process											owl:Class	
GO:2000234	biolink:NamedThing	positive regulation of rRNA processing	Any process that activates or increases the frequency, rate or extent of rRNA processing.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of 35S primary transcript processing							mah	2010-11-10T12:11:36Z					biological_process											owl:Class	
GO:0090419	biolink:NamedThing	negative regulation of transcription involved in G2/M transition of mitotic cell cycle	Any process that inhibits or decreases the frequency, rate or extent of transcription of target genes that are transcribed as part of the G2/M transition of the mitotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of transcription from RNA polymerase II promoter during G2/M transition of the mitotic cell cycle|down-regulation of transcription from RNA polymerase II promoter during the G2/M transition of the mitotic cell cycle							tb	2011-10-26T03:59:41Z					biological_process											owl:Class	
GO:0000086	biolink:NamedThing	G2/M transition of mitotic cell cycle	The mitotic cell cycle transition by which a cell in G2 commits to M phase. The process begins when the kinase activity of M cyclin/CDK complex reaches a threshold high enough for the cell cycle to proceed. This is accomplished by activating a positive feedback loop that results in the accumulation of unphosphorylated and active M cyclin/CDK complex.	tmpzr1t_l9r_go_relaxed.owl	mitotic G2/M transition													biological_process											owl:Class	
GO:0090184	biolink:NamedThing	positive regulation of kidney development	Any process that increases the rate, frequency or extent of kidney development. Kidney development is the process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of nephrogenesis							tb	2009-12-18T10:52:01Z					biological_process											owl:Class	
GO:1904376	biolink:NamedThing	negative regulation of protein localization to cell periphery	Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cell periphery.	tmpzr1t_l9r_go_relaxed.owl	downregulation of protein localization to cell periphery|inhibition of protein localization to cell periphery|down regulation of protein localization to cell periphery|down-regulation of protein localization to cell periphery							sl	2015-06-22T22:09:32Z					biological_process											owl:Class	
GO:0030398	biolink:NamedThing	peroxisomal membrane disassembly	The controlled breakdown of the membranes of cargo-carrying vesicles formed during peroxisome degradation.	tmpzr1t_l9r_go_relaxed.owl	peroxisomal membrane breakdown|peroxisomal membrane degradation|peroxisomal membrane catabolism													biological_process											owl:Class	
GO:0030242	biolink:NamedThing	autophagy of peroxisome	The process in which peroxisomes are delivered to a type of vacuole and degraded in response to changing nutrient conditions.	tmpzr1t_l9r_go_relaxed.owl	peroxisome degradation|pexophagy													biological_process											owl:Class	
GO:0072207	biolink:NamedThing	metanephric epithelium development	The process whose specific outcome is the progression of an epithelium in the metanephros over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-03-18T11:50:37Z					biological_process											owl:Class	
GO:0048213	biolink:NamedThing	Golgi vesicle prefusion complex stabilization	The binding of specific proteins to the t-SNARE/v-SNARE/SNAP25 complex, by which the Golgi vesicle prefusion complex is stabilized.	tmpzr1t_l9r_go_relaxed.owl	dictyosome vesicle prefusion complex stabilisation|Golgi-derived vesicle prefusion complex stabilization|Golgi vesicle prefusion complex assembly													biological_process											owl:Class	
GO:0060576	biolink:NamedThing	intestinal epithelial cell development	The process whose specific outcome is the progression of a columnar/cuboidal epithelial cell of the intestine over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-05-06T08:20:24Z					biological_process											owl:Class	
GO:0007314	biolink:NamedThing	oocyte anterior/posterior axis specification	Polarization of the oocyte along its anterior-posterior axis. An example of this is found in Drosophila melanogaster.	tmpzr1t_l9r_go_relaxed.owl	oocyte anterior/posterior axis determination											GO:0048112		biological_process											owl:Class	
GO:1905921	biolink:NamedThing	regulation of acetylcholine biosynthetic process	Any process that modulates the frequency, rate or extent of acetylcholine biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of acetylcholine formation|regulation of acetylcholine anabolism|regulation of acetylcholine biosynthesis|regulation of acetylcholine synthesis							bc	2017-02-08T13:08:30Z					biological_process											owl:Class	
GO:0008292	biolink:NamedThing	acetylcholine biosynthetic process	The chemical reactions and pathways resulting in the formation of acetylcholine, the acetic acid ester of the organic base choline.	tmpzr1t_l9r_go_relaxed.owl	acetylcholine biosynthesis|acetylcholine synthesis|acetylcholine formation|acetylcholine anabolism													biological_process											owl:Class	
GO:0048912	biolink:NamedThing	glial cell migration in anterior lateral line nerve	The movement of a glial cell along the axons in the anterior lateral line nerve.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0048909	biolink:NamedThing	anterior lateral line nerve development	The process whose specific outcome is the progression of the anterior lateral line nerve over time, form its formation to the mature structure. The anterior lateral line nerve contains efferent axons that innervate hair cells of the ALL and afferent axons that project to an octavolateralis column in the hindbrain. The octavolateralis column consists of the medial octavolateralis nucleus (MON), the caudal octavolateralis nucleus, and the magnocellular nucleus.	tmpzr1t_l9r_go_relaxed.owl	nALL development|rostral lateral line nerve development|ALLN development											GO:0021734		biological_process											owl:Class	
GO:0032324	biolink:NamedThing	molybdopterin cofactor biosynthetic process	The chemical reactions and pathways resulting in the formation of the molybdopterin cofactor (Moco), essential for the catalytic activity of some enzymes, e.g. sulfite oxidase, xanthine dehydrogenase, and aldehyde oxidase. The cofactor consists of a mononuclear molybdenum (Mo-molybdopterin) or tungsten ion (W-molybdopterin) coordinated by one or two molybdopterin ligands.	tmpzr1t_l9r_go_relaxed.owl	molybdopterin cofactor anabolism|molybdopterin cofactor synthesis|molybdopterin cofactor formation|molybdopterin cofactor biosynthesis				MetaCyc:Molybdenum-Cofactor-Biosynthesis									biological_process											owl:Class	
GO:0030366	biolink:NamedThing	molybdopterin synthase activity	Catalysis of the conversion of precursor Z to molybdopterin, the final step in molybdopterin biosynthesis.	tmpzr1t_l9r_go_relaxed.owl					RHEA:26333|Reactome:R-HSA-947541|EC:2.8.1.12									molecular_function											owl:Class	
GO:0002351	biolink:NamedThing	serotonin production involved in inflammatory response	The synthesis or release of serotonin following a stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels.	tmpzr1t_l9r_go_relaxed.owl	serotonin production involved in acute inflammatory response													biological_process											owl:Class	
GO:1903930	biolink:NamedThing	regulation of pyrimidine-containing compound salvage	Any process that modulates the frequency, rate or extent of pyrimidine-containing compound salvage.	tmpzr1t_l9r_go_relaxed.owl	regulation of pyrimidine salvage							al	2015-02-12T14:09:05Z					biological_process											owl:Class	
GO:0008655	biolink:NamedThing	pyrimidine-containing compound salvage	Any process that generates a pyrimidine-containing compound, a nucleobase, nucleoside, nucleotide or nucleic acid that contains a pyrimidine base, from derivatives of them without de novo synthesis.	tmpzr1t_l9r_go_relaxed.owl	pyrimidine salvage													biological_process											owl:Class	
GO:0015138	biolink:NamedThing	fumarate transmembrane transporter activity	Enables the transfer of fumarate from one side of a membrane to the other. Fumarate is a key intermediate in metabolism and is formed in the TCA cycle from succinate and converted into malate.	tmpzr1t_l9r_go_relaxed.owl	dicarboxylate (succinate/fumarate/malate) antiporter activity													molecular_function											owl:Class	
GO:0015741	biolink:NamedThing	fumarate transport	The directed movement of fumarate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0048266	biolink:NamedThing	behavioral response to pain	Any process that results in a change in the behavior of an organism as a result of a pain stimulus. Pain stimuli cause activation of nociceptors, peripheral receptors for pain, include receptors which are sensitive to painful mechanical stimuli, extreme heat or cold, and chemical stimuli.	tmpzr1t_l9r_go_relaxed.owl	behavioural response to pain													biological_process											owl:Class	
GO:0048265	biolink:NamedThing	response to pain	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pain stimulus. Pain stimuli cause activation of nociceptors, peripheral receptors for pain, include receptors which are sensitive to painful mechanical stimuli, extreme heat or cold, and chemical stimuli.	tmpzr1t_l9r_go_relaxed.owl	physiological response to pain											GO:0048267		biological_process											owl:Class	
GO:1903138	biolink:NamedThing	negative regulation of cell wall integrity MAPK cascade	Any process that stops, prevents or reduces the frequency, rate or extent of MAPK cascade involved in cell wall organization or biogenesis.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of Pmk1 MAPK cell integrity signaling|down regulation of MAPK cascade involved in cell wall biogenesis|inhibition of MAPK cascade involved in cell wall organization or biogenesis|down regulation of Pmk1 MAPK cell integrity signaling|negative regulation of MAPKKK cascade involved in cell wall biogenesis|down regulation of cell integrity MAPK pathway|downregulation of Mpk1 cascade|down regulation of Mpk1 cascade|negative regulation of cell integrity MAPK pathway|downregulation of PMK1-MAPK signal transduction pathway|negative regulation of MAPK cascade involved in cell wall organization or biogenesis|inhibition of PMK1-MAPK signal transduction pathway|inhibition of cell wall biogenesis, MAPKKK cascade|downregulation of MAPK cascade involved in cell wall biogenesis|negative regulation of MAPK cascade involved in cell wall biogenesis|down-regulation of MAPK cascade involved in cell wall biogenesis|downregulation of Slt2 cascade|down regulation of PMK1-MAPK signal transduction pathway|downregulation of Pmk1 mitogen-activated protein kinase (MAPK) cell integrity pathway|inhibition of Pmk1 mitogen-activated protein kinase (MAPK) cell integrity pathway|downregulation of MAPKKK cascade involved in cell wall biogenesis|negative regulation of Mpk1 cascade|down regulation of Pmk1 mitogen-activated protein kinase (MAPK) cell integrity pathway|down regulation of MAPK cascade involved in cell wall organization or biogenesis|negative regulation of Slt2 cascade|inhibition of Slt2 cascade|down-regulation of Slt2 cascade|negative regulation of PMK1-MAPK signal transduction pathway|inhibition of MAPK cascade involved in cell wall biogenesis|downregulation of cell integrity MAPK pathway|down-regulation of Mpk1 cascade|down-regulation of PMK1-MAPK signal transduction pathway|down-regulation of cell wall biogenesis, MAPKKK cascade|inhibition of Pmk1 MAPK cell integrity signaling|down-regulation of Pmk1 MAPK cell integrity signaling|down-regulation of MAPKKK cascade involved in cell wall biogenesis|downregulation of MAPK cascade involved in cell wall organization or biogenesis|down regulation of cell wall biogenesis, MAPKKK cascade|down-regulation of Pmk1 mitogen-activated protein kinase (MAPK) cell integrity pathway|down regulation of Slt2 cascade|inhibition of MAPKKK cascade involved in cell wall biogenesis|negative regulation of Pmk1 mitogen-activated protein kinase (MAPK) cell integrity pathway|downregulation of cell wall biogenesis, MAPKKK cascade|down-regulation of cell integrity MAPK pathway|down regulation of MAPKKK cascade involved in cell wall biogenesis|down-regulation of MAPK cascade involved in cell wall organization or biogenesis|inhibition of Mpk1 cascade|downregulation of Pmk1 MAPK cell integrity signaling|negative regulation of cell wall biogenesis, MAPKKK cascade|inhibition of cell integrity MAPK pathway	https://github.com/geneontology/go-ontology/issues/20131						mah	2014-07-01T10:21:59Z					biological_process											owl:Class	
GO:0000196	biolink:NamedThing	cell wall integrity MAPK cascade	A MAPK cascade that contributes to cell wall organization or biogenesis.	tmpzr1t_l9r_go_relaxed.owl	PMK1-MAPK signal transduction pathway|cell wall biogenesis, MAPKKK cascade|Pmk1 mitogen-activated protein kinase (MAPK) cell integrity pathway|Pmk1 MAPK cell integrity signaling|MAPK cascade involved in cell wall organization or biogenesis|Mpk1 cascade|cell integrity MAPK pathway|MAPK cascade involved in cell wall biogenesis|Slt2 cascade|MAPKKK cascade involved in cell wall biogenesis													biological_process											owl:Class	
GO:0061224	biolink:NamedThing	mesonephric glomerulus development	The progression of the mesonephric glomerulus over time from its initial formation until its mature state. The mesonephric glomerulus is a capillary tuft which forms a close network with the visceral epithelium (podocytes) and the mesangium to form the filtration barrier and is surrounded by Bowman's capsule in nephrons of the mature vertebrate kidney, or mesonephros.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-08-19T01:26:00Z					biological_process											owl:Class	
GO:0035721	biolink:NamedThing	intraciliary retrograde transport	The directed movement of large protein complexes along microtubules from the tip of a cilium (also called flagellum) toward the cell body, mediated by motor proteins.	tmpzr1t_l9r_go_relaxed.owl	intraflagellar retrograde transport					Note that we deem cilium and microtubule-based flagellum to be equivalent.		bf	2011-03-07T11:25:32Z					biological_process											owl:Class	
GO:0045650	biolink:NamedThing	negative regulation of macrophage differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of macrophage differentiation.	tmpzr1t_l9r_go_relaxed.owl	inhibition of macrophage differentiation|downregulation of macrophage differentiation|down regulation of macrophage differentiation|down-regulation of macrophage differentiation													biological_process											owl:Class	
GO:0030080	biolink:NamedThing	B875 antenna complex	Protein complex that surrounds and transfers excitation energy directly to the bacterial reaction center; binds bacteriochlorophyll a and has a single absorption band between 870 and 890 nm.	tmpzr1t_l9r_go_relaxed.owl	LH1 complex|light harvesting complex I													cellular_component											owl:Class	
GO:0030078	biolink:NamedThing	light-harvesting complex, core complex	Light harvesting complex associated with the reaction complex of photosynthetic purple bacteria.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:1990768	biolink:NamedThing	gastric mucosal blood circulation	The flow of blood through the gastric mucosa of an animal, enabling the transport of nutrients and the removal of waste products.	tmpzr1t_l9r_go_relaxed.owl	stomach mucosal blood circulation							sl	2015-06-10T20:11:09Z					biological_process											owl:Class	
GO:0014844	biolink:NamedThing	myoblast proliferation involved in skeletal muscle regeneration	The multiplication or reproduction of myoblasts, resulting in the expansion of the cell population. This occurs as part of skeletal muscle regeneration. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0005763	biolink:NamedThing	mitochondrial small ribosomal subunit	The smaller of the two subunits of a mitochondrial ribosome.	tmpzr1t_l9r_go_relaxed.owl	28S ribosomal subunit, mitochondrial|mitochondrial ribosomal small subunit complex|mitochondrial ribosomal SSU complex													cellular_component											owl:Class	
GO:0005761	biolink:NamedThing	mitochondrial ribosome	A ribosome found in the mitochondrion of a eukaryotic cell; contains a characteristic set of proteins distinct from those of cytosolic ribosomes.	tmpzr1t_l9r_go_relaxed.owl	55S ribosome, mitochondrial													cellular_component											owl:Class	
GO:1902148	biolink:NamedThing	positive regulation of response to cytokinesis checkpoint signaling	Any process that activates or increases the frequency, rate or extent of response to cytokinesis checkpoint signaling.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of response to signal involved in cytokinesis checkpoint|up-regulation of cytokinesis checkpoint effector process|up regulation of response to cytokinesis checkpoint signaling|activation of response to cytokinesis checkpoint signaling|activation of cytokinesis checkpoint effector process|positive regulation of cytokinesis checkpoint effector process|up regulation of cytokinesis checkpoint effector process|upregulation of cytokinesis checkpoint effector process|up-regulation of response to signal involved in cytokinesis checkpoint|up-regulation of response to cytokinesis checkpoint signaling|activation of response to signal involved in cytokinesis checkpoint|up regulation of response to signal involved in cytokinesis checkpoint|upregulation of response to cytokinesis checkpoint signaling|upregulation of response to signal involved in cytokinesis checkpoint							jl	2013-05-21T15:43:58Z			GO:1902150		biological_process											owl:Class	
GO:0072399	biolink:NamedThing	response to cytokinesis checkpoint signaling	A process that occurs in response to signals generated as a result of cytokinesis checkpoint signaling.	tmpzr1t_l9r_go_relaxed.owl	response to signal involved in cytokinesis checkpoint|cytokinesis checkpoint effector process							mah	2010-12-08T03:23:32Z			GO:0072420		biological_process											owl:Class	
GO:0042316	biolink:NamedThing	penicillin metabolic process	The chemical reactions and pathways involving any antibiotic that contains the condensed beta-lactamthiazolidine ring system. Penicillins are produced naturally during the growth of various microfungi of the genera Penicillium and Aspergillus.	tmpzr1t_l9r_go_relaxed.owl	penicillin metabolism													biological_process											owl:Class	
GO:0035677	biolink:NamedThing	posterior lateral line neuromast hair cell development	The process whose specific outcome is the progression of a posterior lateral line neuromast hair cell over time, from its formation to the mature structure. A neuromast hair cell is a hair cell that acts as a sensory receptor of the neuromast; it is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. Cell development does not include the steps involved in committing a cell to a specific fate.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-02-14T11:04:57Z					biological_process											owl:Class	
GO:0048923	biolink:NamedThing	posterior lateral line neuromast hair cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a posterior lateral line neuromast hair cell. (N.B. This may be development of neuromast hair cell type or a set of cell of neuromast hair cell type. This will involve the change of a cell or set of cells from one cell identity to another). Hair cells are the sensory receptors of the neuromast and are located in a portion of the neuromast called the sensory strip. Each hair cell of the neuromast is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. There are approximately seven hair cells within each neuromast, with each hair cell innervated by afferent and efferent neurons.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0060721	biolink:NamedThing	regulation of spongiotrophoblast cell proliferation	Any process that modulates the rate, frequency or extent of spongiotrophoblast cell proliferation.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-06-11T09:57:27Z					biological_process											owl:Class	
GO:0060720	biolink:NamedThing	spongiotrophoblast cell proliferation	The multiplication or reproduction of spongiotrophoblast cells, resulting in the expansion of the population in the spongiotrophoblast layer.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-06-11T09:50:35Z					biological_process											owl:Class	
GO:1903528	biolink:NamedThing	regulation of dCDP biosynthetic process	Any process that modulates the frequency, rate or extent of dCDP biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of dCDP synthesis|regulation of dCDP biosynthesis|regulation of dCDP formation|regulation of dCDP anabolism							al	2014-10-07T15:01:18Z					biological_process											owl:Class	
GO:0006240	biolink:NamedThing	dCDP biosynthetic process	The chemical reactions and pathways resulting in the formation of dCDP, deoxycytidine 5'-diphosphate.	tmpzr1t_l9r_go_relaxed.owl	dCDP synthesis|dCDP anabolism|dCDP formation|dCDP biosynthesis													biological_process											owl:Class	
GO:0051630	biolink:NamedThing	acetylcholine uptake	The directed movement of acetylcholine into a cell, typically presynaptic neurons or glial cells. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues.	tmpzr1t_l9r_go_relaxed.owl	acetylcholine import													biological_process											owl:Class	
GO:0045603	biolink:NamedThing	positive regulation of endothelial cell differentiation	Any process that activates or increases the frequency, rate or extent of endothelial cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	up regulation of endothelial cell differentiation|stimulation of endothelial cell differentiation|activation of endothelial cell differentiation|up-regulation of endothelial cell differentiation|upregulation of endothelial cell differentiation													biological_process											owl:Class	
GO:0045446	biolink:NamedThing	endothelial cell differentiation	The process in which a mesodermal, bone marrow or neural crest cell acquires specialized features of an endothelial cell, a thin flattened cell. A layer of such cells lines the inside surfaces of body cavities, blood vessels, and lymph vessels, making up the endothelium.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0051258	biolink:NamedThing	protein polymerization	The process of creating protein polymers, compounds composed of a large number of component monomers; polymeric proteins may be made up of different or identical monomers. Polymerization occurs by the addition of extra monomers to an existing poly- or oligomeric protein.	tmpzr1t_l9r_go_relaxed.owl	protein polymer biosynthetic process|protein polymer formation|protein polymer biosynthesis													biological_process											owl:Class	
GO:0004326	biolink:NamedThing	tetrahydrofolylpolyglutamate synthase activity	Catalysis of the reaction: ATP + tetrahydrofolyl-(Glu)(n) + L-glutamate = ADP + phosphate + tetrahydrofolyl-(Glu)(n+1).	tmpzr1t_l9r_go_relaxed.owl	folylpoly-gamma-glutamate synthetase-dihydrofolate synthetase activity|folylpoly-gamma-glutamate synthase activity|folylpolyglutamyl synthetase activity|N10-formyltetrahydropteroyldiglutamate synthetase activity|tetrahydropteroyl-[gamma-polyglutamate]:L-glutamate gamma-ligase (ADP-forming)|tetrahydrofolate synthase activity|folylpolyglutamate synthetase activity|folylpolyglutamate synthase activity|formyltetrahydropteroyldiglutamate synthetase activity|tetrahydrofolate:L-glutamate gamma-ligase (ADP-forming) activity|tetrahydrofolyl-[gamma-Glu]n:L-glutamate gamma-ligase (ADP-forming)|FPGS activity|folylpoly(gamma-glutamate) synthase activity|N(10)-formyltetrahydropteroyldiglutamate synthetase activity|folate polyglutamate synthetase activity				RHEA:10580|Reactome:R-HSA-200682|Reactome:R-HSA-197958|EC:6.3.2.17|MetaCyc:FOLYLPOLYGLUTAMATESYNTH-RXN|Reactome:R-HSA-200681									molecular_function											owl:Class	
GO:0046901	biolink:NamedThing	tetrahydrofolylpolyglutamate biosynthetic process	The chemical reactions and pathways resulting in the formation of tetrahydrofolylpolyglutamate, a folate derivative comprising tetrahydrofolate attached to a chain of glutamate residues.	tmpzr1t_l9r_go_relaxed.owl	tetrahydrofolylpolyglutamate formation|THF polyglutamylation|tetrahydrofolyl-[Glu](n) biosynthesis|tetrahydrofolyl-[Glu](n) biosynthetic process|tetrahydrofolylpolyglutamate biosynthesis|tetrahydrofolylpolyglutamate synthesis|tetrahydrofolylpolyglutamate anabolism|tetrahydrofolate polyglutamylation|folic acid-containing compound polyglutamylation													biological_process											owl:Class	
GO:0048916	biolink:NamedThing	posterior lateral line development	The process whose specific outcome is the progression of the posterior lateral line over time, from its formation to the mature structure. The posterior lateral line consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the body and trunk of all fishes and most amphibians. The posterior lateral line develops from cranial ectodermal placodes situated behind the ear.	tmpzr1t_l9r_go_relaxed.owl	PLL development													biological_process											owl:Class	
GO:0048915	biolink:NamedThing	posterior lateral line system development	The process whose specific outcome is the progression of the posterior lateral line system over time, from its formation to the mature structure. The posterior lateral line system develops from cranial ectodermal placodes, situated behind the ear, that give rise to both the neuromasts and the posterior lateral line sensory nerves that innervate the neuromasts. The posterior lateral line system consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the head of all fishes and most amphibians. The neuromasts are innervated by several lateral line nerves, which project primarily to the hindbrain. The posterior mechanosensory lateral line system is stimulated by local water displacements and vibrations, and detects propulsion of the fish through the water, as well as facilitating shoaling, prey capture, and predator and obstacle avoidance.	tmpzr1t_l9r_go_relaxed.owl	PLL													biological_process											owl:Class	
GO:0048801	biolink:NamedThing	antennal joint morphogenesis	The process in which the anatomical structures of the antennal joint are generated and organized.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:2001177	biolink:NamedThing	negative regulation of mediator complex assembly	Any process that stops, prevents or reduces the frequency, rate or extent of mediator complex assembly.	tmpzr1t_l9r_go_relaxed.owl								yaf	2011-11-02T11:22:23Z					biological_process											owl:Class	
GO:1903706	biolink:NamedThing	regulation of hemopoiesis	Any process that modulates the frequency, rate or extent of hemopoiesis.	tmpzr1t_l9r_go_relaxed.owl	regulation of blood cell formation|regulation of haemopoiesis|regulation of hematopoiesis|regulation of blood cell biosynthesis					An example of this is Atg7 in mouse (UniProt symbol, Q9D906) in PMID:20080761, inferred from mutant phenotype.		pad	2014-12-04T15:34:13Z					biological_process											owl:Class	
GO:0060540	biolink:NamedThing	diaphragm morphogenesis	The process in which the anatomical structures of the diaphragm are generated and organized.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-04-10T08:47:51Z					biological_process											owl:Class	
GO:0060539	biolink:NamedThing	diaphragm development	The progression of the diaphragm over time from its initial formation to the mature structure. The diaphragm is a skeletal muscle that is responsible for contraction and expansion of the lungs.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-04-10T08:44:56Z					biological_process											owl:Class	
GO:0070576	biolink:NamedThing	vitamin D 24-hydroxylase activity	Catalysis of the hydroxylation of C-24 of any form of vitamin D.	tmpzr1t_l9r_go_relaxed.owl	ergocalciferol 24-hydroxylase activity|vitamin D2 24-hydroxylase activity|calciferol 24-hydroxylase activity|cholecalciferol 24-hydroxylase activity|vitamin D3 24-hydroxylase activity							mah	2009-04-21T02:20:52Z					molecular_function											owl:Class	
GO:1904429	biolink:NamedThing	regulation of t-circle formation	Any process that modulates the frequency, rate or extent of t-circle formation.	tmpzr1t_l9r_go_relaxed.owl	regulation of telomeric circle formation							nc	2015-07-03T15:15:45Z					biological_process											owl:Class	
GO:0015986	biolink:NamedThing	ATP synthesis coupled proton transport	The transport of protons across a membrane to generate an electrochemical gradient (proton-motive force) that powers ATP synthesis.	tmpzr1t_l9r_go_relaxed.owl	chemiosmosis													biological_process											owl:Class	
GO:0002003	biolink:NamedThing	angiotensin maturation	The process leading to the attainment of the full functional capacity of angiotensin by conversion of angiotensinogen into mature angiotensin in the blood.	tmpzr1t_l9r_go_relaxed.owl	angiotensin catabolic process in blood											GO:0002005		biological_process											owl:Class	
GO:0002002	biolink:NamedThing	regulation of angiotensin levels in blood	The process that modulates the level of any of the various angiotensinogen proteolytic products in the blood. This occurs by the proteolytic cleavage of angiotensinogen, and its proteolytic products, to create a variety of active peptide hormones, such as angiotensin I and angiotensin II, as well as through the removal of these peptides from the circulation.	tmpzr1t_l9r_go_relaxed.owl	control of blood angiotensin level|regulation of blood angiotensin level|control of angiotensin levels in blood	https://github.com/geneontology/go-ontology/issues/15424												biological_process											owl:Class	
GO:0003311	biolink:NamedThing	pancreatic D cell differentiation	The process in which relatively unspecialized cells acquire specialized structural and functional features that characterize a pancreatic delta cell. A delta cell is a cell of the pancreas that produces somatostatin.	tmpzr1t_l9r_go_relaxed.owl	pancreatic delta cell differentiation							dph	2009-10-26T09:30:27Z					biological_process											owl:Class	
GO:0031018	biolink:NamedThing	endocrine pancreas development	The process whose specific outcome is the progression of the endocrine pancreas over time, from its formation to the mature structure. The endocrine pancreas is made up of islet cells that produce insulin, glucagon and somatostatin.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0008195	biolink:NamedThing	phosphatidate phosphatase activity	Catalysis of the reaction: a 1,2-diacylglycerol 3-phosphate + H2O = a 1,2-diacyl-sn-glycerol + phosphate.	tmpzr1t_l9r_go_relaxed.owl	phosphatic acid phosphohydrolase activity|phosphatic acid phosphatase activity|phosphatidic acid phosphatase activity|phosphatidate phosphohydrolase activity|3-sn-phosphatidate phosphohydrolase activity|acid phosphatidyl phosphatase activity				Reactome:R-HSA-1483203|Reactome:R-HSA-75899|Reactome:R-HSA-163750|Reactome:R-HSA-163689|EC:3.1.3.4|Reactome:R-HSA-164056|Reactome:R-HSA-2029468|Reactome:R-HSA-390329|MetaCyc:PHOSPHATIDATE-PHOSPHATASE-RXN|RHEA:27429|Reactome:R-HSA-6797630|Reactome:R-HSA-5221130|Reactome:R-HSA-163688							GO:0004606		molecular_function											owl:Class	
GO:0043301	biolink:NamedThing	negative regulation of leukocyte degranulation	Any process that stops, prevents, or reduces the rate of leukocyte degranulation.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of leucocyte degranulation|down regulation of leukocyte degranulation|down-regulation of leukocyte degranulation|inhibition of leukocyte degranulation|downregulation of leukocyte degranulation|negative regulation of immune cell degranulation													biological_process											owl:Class	
GO:0048388	biolink:NamedThing	endosomal lumen acidification	Any process that reduces the pH of the endosomal lumen, measured by the concentration of the hydrogen ion.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0007032	biolink:NamedThing	endosome organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of endosomes.	tmpzr1t_l9r_go_relaxed.owl	endosome organization and biogenesis|endosome organisation													biological_process											owl:Class	
GO:0021796	biolink:NamedThing	cerebral cortex regionalization	The regionalization process that results in the creation of areas within the cerebral cortex that will direct the behavior of cell migration and differentiation as the cortex develops.	tmpzr1t_l9r_go_relaxed.owl	cerebral cortex arealization|cerebral cortex pattern formation|cerebral cortex pattern biosynthesis													biological_process											owl:Class	
GO:0005579	biolink:NamedThing	membrane attack complex	A protein complex produced by sequentially activated components of the complement cascade inserted into a target cell membrane and forming a pore leading to cell lysis via ion and water flow.	tmpzr1t_l9r_go_relaxed.owl	membrane attack complex protein beta2 chain|MAC|TCC|terminal complement complex|membrane attack complex protein alphaM chain				Wikipedia:Complement_membrane_attack_complex									cellular_component											owl:Class	
GO:0032534	biolink:NamedThing	regulation of microvillus assembly	A process that modulates the formation of a microvillus.	tmpzr1t_l9r_go_relaxed.owl	regulation of microvillus biogenesis													biological_process											owl:Class	
GO:0030033	biolink:NamedThing	microvillus assembly	Formation of a microvillus, a thin cylindrical membrane-covered projection on the surface of a cell.	tmpzr1t_l9r_go_relaxed.owl	microvillus biogenesis													biological_process											owl:Class	
GO:0033583	biolink:NamedThing	rhabdomere membrane	The portion of the plasma membrane surrounding the rhabdomere.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0016028	biolink:NamedThing	rhabdomere	The specialized microvilli-containing organelle on the apical surfaces of a photoreceptor cell containing the visual pigment rhodopsin and most of the proteins involved in phototransduction.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0002007	biolink:NamedThing	detection of hypoxic conditions in blood by chemoreceptor signaling	The process in which information about a lack of oxygen are received and are converted to a molecular signal by chemoreceptors in the carotid bodies and the aortic bodies.	tmpzr1t_l9r_go_relaxed.owl	detection of hypoxic conditions in blood by chemoreceptor signalling													biological_process											owl:Class	
GO:0021697	biolink:NamedThing	cerebellar cortex formation	The process that gives rise to the cerebellar cortex. This process pertains to the initial formation of a structure from unspecified parts. The cerebellar cortex is a thin mantle of gray matter that covers the surface of each cerebral hemisphere. It has a characteristic morphology with convolutions (gyri) and crevices (sulci) that have specific functions. Six layers of nerve cells and the nerve pathways that connect them comprise the cerebellar cortex. Together, these regions are responsible for the processes of conscious thought, perception, emotion and memory as well as advanced motor function.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0009526	biolink:NamedThing	plastid envelope	The double lipid bilayer enclosing a plastid and separating its contents from the rest of the cytoplasm; includes the intermembrane space.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0014052	biolink:NamedThing	regulation of gamma-aminobutyric acid secretion	Any process that modulates the frequency, rate or extent of the regulated release of gamma-aminobutyric acid.	tmpzr1t_l9r_go_relaxed.owl	regulation of GABA secretion													biological_process											owl:Class	
GO:1900146	biolink:NamedThing	negative regulation of nodal signaling pathway involved in determination of left/right asymmetry	Any process that stops, prevents or reduces the frequency, rate or extent of a nodal signaling pathway, where the nodal signaling pathway is involved in determination of left/right asymmetry.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of nodal signaling pathway involved in determination of left/right asymmetry|inhibition of nodal signaling pathway involved in determination of left/right asymmetry|negative regulation of nodal signalling pathway involved in determination of left/right asymmetry|down regulation of nodal signaling pathway involved in determination of left/right asymmetry|downregulation of nodal signaling pathway involved in determination of left/right asymmetry							bf	2012-03-06T11:00:36Z					biological_process											owl:Class	
GO:0038107	biolink:NamedThing	nodal signaling pathway involved in determination of left/right asymmetry	A series of molecular signals initiated by the binding of a nodal protein to an activin receptor on the surface of a target cell, which contributes to the establishment of an organism's body plan or part of an organism with respect to the left and right halves.	tmpzr1t_l9r_go_relaxed.owl	nodal signalling pathway involved in determination of left/right asymmetry|regulation of transcription from RNA polymerase II promoter by nodal signaling pathway, involved in determination of left/right symmetry							bf	2012-02-29T10:18:59Z					biological_process											owl:Class	
GO:2000236	biolink:NamedThing	negative regulation of tRNA processing	Any process that stops, prevents, or reduces the frequency, rate or extent of tRNA processing.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of tRNA maturation							mah	2010-11-10T12:15:13Z					biological_process											owl:Class	
GO:0120228	biolink:NamedThing	outer dynein arm docking complex	A complex which stabilizes the binding of and correctly positions the outer dynein arm complex along an A-tubule of the flagellar axoneme outer doublet microtubules.	tmpzr1t_l9r_go_relaxed.owl	ODA docking complex|ODA-DC	https://github.com/geneontology/go-ontology/issues/19588						krc	2020-06-05T23:30:44Z					cellular_component											owl:Class	
GO:1905140	biolink:NamedThing	regulation of apical ectodermal ridge formation	Any process that modulates the frequency, rate or extent of apical ectodermal ridge formation.	tmpzr1t_l9r_go_relaxed.owl	regulation of apical epidermal ridge formation|regulation of AER formation|regulation of crista ectodermalis apicalis formation							dph	2016-04-13T12:16:40Z					biological_process											owl:Class	
GO:0071007	biolink:NamedThing	U2-type catalytic step 2 spliceosome	A spliceosomal complex that contains the U2, U5 and U6 snRNPs bound to a splicing intermediate in which the first catalytic cleavage of the 5' splice site has occurred. The precise subunit composition differs significantly from that of the catalytic step 1, or activated, spliceosome, and includes many proteins in addition to those found in the U2, U5 and U6 snRNPs.	tmpzr1t_l9r_go_relaxed.owl	mammalian U2-type spliceosomal complex C|major catalytic step 2 spliceosome|GT-AG catalytic step 2 spliceosome|yeast U2-type spliceosomal complex A2-2|mammalian U2-type spliceosomal complex C1							mah	2009-07-30T12:00:35Z					cellular_component											owl:Class	
GO:0005688	biolink:NamedThing	U6 snRNP	A ribonucleoprotein complex that contains small nuclear RNA U6, the Lsm2-8 heptameric ring complex, as well as several proteins that are unique to the U6 snRNP, most of which remain associated with the U6 snRNA both while the U6 snRNP is free or assembled into the U4/U6 snRNP or into a series of spliceosomal complexes.	tmpzr1t_l9r_go_relaxed.owl	snRNP U6													cellular_component											owl:Class	
GO:0048657	biolink:NamedThing	anther wall tapetum cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of an anther cell wall tapetum cell. The tapetum is a layer of cells that provides a source of nutrition for the pollen grains as they mature.	tmpzr1t_l9r_go_relaxed.owl	tapetal cell differentiation													biological_process											owl:Class	
GO:0004465	biolink:NamedThing	lipoprotein lipase activity	Catalysis of the reaction: triacylglycerol + H2O = diacylglycerol + a carboxylate, where the triacylglycerol is part of a lipoprotein.	tmpzr1t_l9r_go_relaxed.owl	clearing factor lipase activity|postheparin esterase activity|diacylglycerol lipase activity|postheparin lipase activity|diglyceride lipase activity|triacylglycero-protein acylhydrolase activity|diacylglycerol hydrolase activity|lipemia-clearing factor				Reactome:R-HSA-1482811|Reactome:R-HSA-174757|Reactome:R-HSA-8980228|EC:3.1.1.34|Reactome:R-HSA-6789310|Reactome:R-HSA-2395768|Reactome:R-HSA-8979996|MetaCyc:LIPOPROTEIN-LIPASE-RXN									molecular_function											owl:Class	
GO:0060066	biolink:NamedThing	oviduct development	The reproductive developmental process whose specific outcome is the progression of an oviduct over time, from its formation to the mature structure. An oviduct is a tube through which an ova passes from the ovary to the uterus, or from the ovary to the outside of the organism.	tmpzr1t_l9r_go_relaxed.owl	Mullerian tract development|fallopian tube development													biological_process											owl:Class	
GO:0099174	biolink:NamedThing	regulation of presynapse organization	Any process that modulates the physical form of a presynapse.	tmpzr1t_l9r_go_relaxed.owl	regulation of presynapse organisation|regulation of presynapse organization and biogenesis|regulation of presynapse structure													biological_process											owl:Class	
GO:2000068	biolink:NamedThing	regulation of defense response to insect	Any process that modulates the frequency, rate or extent of defense response to insect.	tmpzr1t_l9r_go_relaxed.owl	regulation of physiological defense response to insect							tb	2010-08-23T09:30:00Z					biological_process											owl:Class	
GO:0002213	biolink:NamedThing	defense response to insect	A response to protect an organism from a directly detected or perceived external threat from an insect or insects to that organism.	tmpzr1t_l9r_go_relaxed.owl	physiological defense response to insect											GO:0002214		biological_process											owl:Class	
GO:0060579	biolink:NamedThing	ventral spinal cord interneuron fate commitment	The process in which the developmental fate of a cell becomes restricted such that it will develop into a ventral spinal cord interneuron. Ventral spinal cord interneurons are cells located in the ventral portion of the spinal cord that transmit signals between sensory and motor neurons and are required for reflexive responses.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-05-07T12:21:13Z					biological_process											owl:Class	
GO:0021513	biolink:NamedThing	spinal cord dorsal/ventral patterning	The process that regulates the coordinated growth and differentiation that establishes the non-random dorsal-ventral spatial arrangement of the spinal cord.	tmpzr1t_l9r_go_relaxed.owl	spinal cord dorsal-ventral patterning|spinal cord dorsoventral patterning													biological_process											owl:Class	
GO:0044600	biolink:NamedThing	protein guanylyltransferase activity	Catalysis of the reaction: GTP + protein = diphosphate + guanylyl-protein; mediates the addition of an guanylyl (guanosine 5'-monophosphate; GMP group) to specific residues of target proteins.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-05-01T04:00:34Z					molecular_function											owl:Class	
GO:0018260	biolink:NamedThing	protein guanylylation	The addition of phospho-guanosine to a protein amino acid.	tmpzr1t_l9r_go_relaxed.owl	protein amino acid guanylylation													biological_process											owl:Class	
GO:1903427	biolink:NamedThing	negative regulation of reactive oxygen species biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of reactive oxygen species biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	inhibition of reactive oxygen species synthesis|down-regulation of reactive oxygen species formation|down-regulation of reactive oxygen species generation|down-regulation of ROS generation|down-regulation of reactive oxygen species biosynthesis|inhibition of reactive oxygen species generation|down-regulation of reactive oxygen species synthesis|inhibition of reactive oxygen species anabolism|down regulation of reactive oxygen species synthesis|down regulation of reactive oxygen species generation|negative regulation of ROS formation|downregulation of ROS generation|downregulation of reactive oxygen species anabolism|down regulation of ROS formation|downregulation of reactive oxygen species biosynthetic process|prevention of ROS generation|negative regulation of reactive oxygen species formation|down regulation of reactive oxygen species formation|inhibition of ROS formation|negative regulation of reactive oxygen species synthesis|down-regulation of reactive oxygen species anabolism|inhibition of reactive oxygen species biosynthetic process|negative regulation of reactive oxygen species anabolism|down regulation of reactive oxygen species biosynthetic process|down regulation of reactive oxygen species biosynthesis|downregulation of reactive oxygen species formation|down regulation of reactive oxygen species anabolism|down regulation of ROS generation|inhibition of ROS generation|inhibition of reactive oxygen species biosynthesis|downregulation of reactive oxygen species biosynthesis|down-regulation of ROS formation|inhibition of reactive oxygen species formation|negative regulation of ROS generation|downregulation of reactive oxygen species generation|negative regulation of reactive oxygen species biosynthesis|downregulation of reactive oxygen species synthesis|negative regulation of reactive oxygen species generation|down-regulation of reactive oxygen species biosynthetic process|downregulation of ROS formation							bf	2014-09-11T10:01:56Z					biological_process											owl:Class	
GO:1903409	biolink:NamedThing	reactive oxygen species biosynthetic process	The chemical reactions and pathways resulting in the formation of reactive oxygen species, any molecules or ions formed by the incomplete one-electron reduction of oxygen.	tmpzr1t_l9r_go_relaxed.owl	reactive oxygen species biosynthesis|reactive oxygen species anabolism|ROS formation|reactive oxygen species synthesis|reactive oxygen species generation|reactive oxygen species formation|ROS generation							bf	2014-09-03T09:19:13Z					biological_process											owl:Class	
GO:0010241	biolink:NamedThing	ent-kaurene oxidation to kaurenoic acid	The three successive oxidations of the 4-methyl group of ent-kaurene to form ent-kaur-16-en-19-oate, kaurenoic acid. This process may be carried out entirely by the enzyme ent-kaurene oxidase.	tmpzr1t_l9r_go_relaxed.owl	ent-kaurene oxidation to ent-kaur-16-en-19-oate|ent-kaurene oxidation to kaurenoic acid by ent-kaurene oxidase|ent-kaurene oxidation to ent-kaurenoate					Note that this term was in molecular function but was moved to biological process as it represents three successive reactions.								biological_process											owl:Class	
GO:0052617	biolink:NamedThing	ent-kaur-16-en-19-al oxidase activity	Catalysis of the reaction: NADPH + ent-kaur-16-en-19-al + oxygen = H2O + NADP+ + ent-kaurenoate.	tmpzr1t_l9r_go_relaxed.owl					EC:1.14.14.86|MetaCyc:RXN-7580|RHEA:10928									molecular_function											owl:Class	
GO:0004445	biolink:NamedThing	inositol-polyphosphate 5-phosphatase activity	Catalysis of the reactions: D-myo-inositol 1,4,5-trisphosphate + H2O = myo-inositol 1,4-bisphosphate + phosphate, and 1D-myo-inositol 1,3,4,5-tetrakisphosphate + H2O = 1D-myo-inositol 1,3,4-trisphosphate + phosphate.	tmpzr1t_l9r_go_relaxed.owl	L-myo-inositol 1,4,5-trisphosphate-monoesterase activity|type I inositol-polyphosphate phosphatase activity|Ins(1,4,5)P(3) 5-phosphatase activity|D-myo-inositol 1,4,5-triphosphate 5-phosphatase activity|Ins(1,4,5)P3/Ins(1,3,4,5)P4 5-phosphatase activity|InsP3/Ins(1,3,4,5)P4 5-phosphatase activity|InsP(3)/Ins(1,3,4,5)P(4) 5-phosphatase activity|inositol triphosphate 5-phosphomonoesterase activity|Ins(1,4,5)P3 5-phosphatase activity|D-myo-inositol 1,4,5-trisphosphate 5-phosphatase activity|1D-myo-inositol-1,4,5-trisphosphate 5-phosphohydrolase activity|myo-inositol-1,4,5-trisphosphate 5-phosphatase activity|type II inositol-1,4,5-trisphosphate 5-phosphatase activity|inositol trisphosphate phosphomonoesterase activity|type II inositol polyphosphate 5-phosphatase activity|inositol phosphate 5-phosphomonoesterase activity|inositol polyphosphate-5-phosphatase activity|5PTase activity|inositol 1,4,5-trisphosphate phosphatase activity|D-myo-inositol(1,4,5)/(1,3,4,5)-polyphosphate 5-phosphatase activity|inositol-1,4,5-trisphosphate/1,3,4,5-tetrakisphosphate 5-phosphatase activity|inositol-1,4,5-trisphosphate 5-phosphatase activity|inosine triphosphatase activity				EC:3.1.3.56	Note that this is a compound function and should be replaced by 'GO:0052659 : inositol 1,3,4,5-tetrakisphosphate 5-phosphatase activity' and 'GO:0052658 : inositol-1,4,5-trisphosphate 5-phosphatase activity'.								molecular_function											owl:Class	
GO:1902663	biolink:NamedThing	negative regulation of peptidyl-L-cysteine S-palmitoylation	Any process that stops, prevents or reduces the frequency, rate or extent of peptidyl-L-cysteine S-palmitoylation.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of peptidyl-S-palmitoyl-L-cysteine formation from peptidyl-cysteine|negative regulation of peptidyl-S-palmitoyl-L-cysteine formation from peptidyl-cysteine|down regulation of peptidyl-S-palmitoyl-L-cysteine anabolism from peptidyl-cysteine|downregulation of peptidyl-S-palmitoyl-L-cysteine anabolism from peptidyl-cysteine|negative regulation of peptidyl-S-palmitoyl-L-cysteine biosynthetic process from peptidyl-cysteine|down-regulation of peptidyl-S-palmitoyl-L-cysteine synthesis from peptidyl-cysteine|negative regulation of peptidyl-cysteine S-palmitoylation|down-regulation of peptidyl-S-palmitoyl-L-cysteine anabolism from peptidyl-cysteine|down-regulation of peptidyl-cysteine S-palmitoylation|down regulation of peptidyl-S-palmitoyl-L-cysteine formation from peptidyl-cysteine|down regulation of peptidyl-L-cysteine S-palmitoylation|inhibition of peptidyl-S-palmitoyl-L-cysteine synthesis from peptidyl-cysteine|inhibition of peptidyl-S-palmitoyl-L-cysteine formation from peptidyl-cysteine|inhibition of peptidyl-cysteine S-palmitoylation|downregulation of peptidyl-L-cysteine S-palmitoylation|negative regulation of peptidyl-S-palmitoyl-L-cysteine anabolism from peptidyl-cysteine|inhibition of peptidyl-S-palmitoyl-L-cysteine anabolism from peptidyl-cysteine|downregulation of peptidyl-S-palmitoyl-L-cysteine synthesis from peptidyl-cysteine|downregulation of peptidyl-S-palmitoyl-L-cysteine formation from peptidyl-cysteine|down regulation of peptidyl-S-palmitoyl-L-cysteine biosynthetic process from peptidyl-cysteine|inhibition of peptidyl-L-cysteine S-palmitoylation|down regulation of peptidyl-S-palmitoyl-L-cysteine synthesis from peptidyl-cysteine|down-regulation of peptidyl-L-cysteine S-palmitoylation|inhibition of peptidyl-S-palmitoyl-L-cysteine biosynthetic process from peptidyl-cysteine|down-regulation of peptidyl-S-palmitoyl-L-cysteine biosynthetic process from peptidyl-cysteine|negative regulation of peptidyl-S-palmitoyl-L-cysteine synthesis from peptidyl-cysteine|down regulation of peptidyl-cysteine S-palmitoylation|downregulation of peptidyl-cysteine S-palmitoylation|downregulation of peptidyl-S-palmitoyl-L-cysteine biosynthetic process from peptidyl-cysteine							mm2	2014-01-29T11:33:19Z					biological_process											owl:Class	
GO:0018230	biolink:NamedThing	peptidyl-L-cysteine S-palmitoylation	The covalent attachment of a palmitoyl group to a sulfur (S) atom within a cysteine residue to form peptidyl-S-palmitoyl-L-cysteine.	tmpzr1t_l9r_go_relaxed.owl	peptidyl-S-palmitoyl-L-cysteine biosynthetic process from peptidyl-cysteine|peptidyl-S-palmitoyl-L-cysteine formation from peptidyl-cysteine|peptidyl-S-palmitoyl-L-cysteine synthesis from peptidyl-cysteine|peptidyl-cysteine S-palmitoylation|peptidyl-S-palmitoyl-L-cysteine anabolism from peptidyl-cysteine				RESID:AA0106	Palmitoylation of a non-terminal cysteine residue always occurs on a sulfur (S) atom.								biological_process											owl:Class	
GO:0014027	biolink:NamedThing	secondary neural tube rod cavitation	The process of medullary cavitation, which is the formation of a lumen in the medullary cord during secondary neurulation, producing the neural tube.	tmpzr1t_l9r_go_relaxed.owl	medullary rod cavitation													biological_process											owl:Class	
GO:0014021	biolink:NamedThing	secondary neural tube formation	The formation of the neural tube by coalescence of mesenchymal cells followed by their conversion to epithelial cells to form a solid cord that subsequently hollows out (cavitates) to create a hollow tube. Secondary neurulation is the typical mechanism of formation of the neural tube posterior to the posterior neuropore in mammals.	tmpzr1t_l9r_go_relaxed.owl	secondary neurulation|medullary cord formation|medullary cord biosynthesis|neural rod formation											GO:0014026		biological_process											owl:Class	
GO:1905020	biolink:NamedThing	positive regulation of methionine-tRNA ligase activity	Any process that activates or increases the frequency, rate or extent of methionine-tRNA ligase activity.	tmpzr1t_l9r_go_relaxed.owl	activation of methionine-tRNA ligase activity|up-regulation of methionine-tRNA ligase activity|activation of methionyl-transfer ribonucleic acid synthetase activity|positive regulation of MetRS activity|up-regulation of methionyl-transfer RNA synthetase activity|positive regulation of methionine translase activity|activation of methionine translase activity|positive regulation of methionyl-transfer RNA synthetase activity|up-regulation of methionyl-transfer ribonucleic acid synthetase activity|upregulation of methionyl-transfer RNA synthetase activity|positive regulation of L-methionine:tRNAMet ligase (AMP-forming)|positive regulation of methionyl-transfer ribonucleic acid synthetase activity|positive regulation of methionyl-transfer ribonucleate synthetase activity|up regulation of MetRS activity|up regulation of methionine translase activity|activation of methionyl-transfer RNA synthetase activity|up regulation of methionyl-transfer ribonucleate synthetase activity|upregulation of MetRS activity|upregulation of methionine-tRNA ligase activity|activation of L-methionine:tRNAMet ligase (AMP-forming)|up regulation of methionyl-transfer ribonucleic acid synthetase activity|activation of MetRS activity|up regulation of methionyl-tRNA synthetase activity|upregulation of methionyl-transfer ribonucleate synthetase activity|upregulation of methionine translase activity|upregulation of L-methionine:tRNAMet ligase (AMP-forming)|upregulation of methionyl-transfer ribonucleic acid synthetase activity|activation of methionyl-tRNA synthetase activity|up-regulation of L-methionine:tRNAMet ligase (AMP-forming)|up regulation of L-methionine:tRNAMet ligase (AMP-forming)|up-regulation of MetRS activity|upregulation of methionyl-tRNA synthetase activity|up regulation of methionyl-transfer RNA synthetase activity|up-regulation of methionyl-tRNA synthetase activity|up regulation of methionine-tRNA ligase activity|positive regulation of methionyl-tRNA synthetase activity|up-regulation of methionyl-transfer ribonucleate synthetase activity|up-regulation of methionine translase activity|activation of methionyl-transfer ribonucleate synthetase activity							sl	2016-03-03T19:02:57Z					biological_process											owl:Class	
GO:0004825	biolink:NamedThing	methionine-tRNA ligase activity	Catalysis of the reaction: ATP + L-methionine + tRNA(Met) = AMP + diphosphate + L-methionyl-tRNA(Met).	tmpzr1t_l9r_go_relaxed.owl	MetRS activity|L-methionine:tRNAMet ligase (AMP-forming)|methionine translase activity|methionyl-tRNA synthetase activity|methionyl-transfer RNA synthetase activity|methionyl-transfer ribonucleate synthetase activity|methionyl-transfer ribonucleic acid synthetase activity				MetaCyc:METHIONINE--TRNA-LIGASE-RXN|RHEA:13481|Reactome:R-HSA-380157|Reactome:R-HSA-379994|EC:6.1.1.10									molecular_function											owl:Class	
GO:0004252	biolink:NamedThing	serine-type endopeptidase activity	Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine).	tmpzr1t_l9r_go_relaxed.owl	blood coagulation factor activity|serine elastase activity				Reactome:R-HSA-381461|Reactome:R-HSA-2168923|Reactome:R-HSA-8855825|Reactome:R-HSA-2482180|Reactome:R-HSA-158747|Reactome:R-HSA-9699007|Reactome:R-HSA-8874212|Reactome:R-HSA-8874206|Reactome:R-HSA-158164|Reactome:R-HSA-2022411|Reactome:R-HSA-1604732|Reactome:R-HSA-1592316|Reactome:R-HSA-1604741|Reactome:R-HSA-9694661|Reactome:R-HSA-3785684|Reactome:R-HSA-183130|Reactome:R-HSA-140696|Reactome:R-HSA-158942|Reactome:R-HSA-183122|Reactome:R-HSA-158137|Reactome:R-HSA-1592436|Reactome:R-HSA-9033515|Reactome:R-HSA-9023196|Reactome:R-HSA-2129357|Reactome:R-HSA-6807224|Reactome:R-HSA-381798|Reactome:R-HSA-1454843|Reactome:R-HSA-9673223|Reactome:R-HSA-9670874|Reactome:R-HSA-166792|Reactome:R-HSA-5607002|Reactome:R-HSA-9033524|Reactome:R-HSA-9033529|Reactome:R-HSA-6800198|Reactome:R-HSA-6800200|Reactome:R-HSA-8874204|Reactome:R-HSA-1474197|Reactome:R-HSA-1602473|Reactome:R-HSA-2214330|Reactome:R-HSA-186785|Reactome:R-HSA-140769|Reactome:R-HSA-170844|Reactome:R-HSA-3928657|Reactome:R-HSA-9023632|Reactome:R-HSA-9653249|Reactome:R-HSA-1566981|Reactome:R-HSA-2168960|Reactome:R-HSA-8874186|Reactome:R-HSA-1592278|Reactome:R-HSA-9033490|Reactome:R-HSA-187020|Reactome:R-HSA-140823|Reactome:R-HSA-159868|Reactome:R-HSA-9033520|Reactome:R-HSA-1592314|Reactome:R-HSA-8850831|Reactome:R-HSA-8865276|Reactome:R-HSA-1912369|Reactome:R-HSA-1602466|Reactome:R-HSA-977371|Reactome:R-HSA-400459|Reactome:R-HSA-173680|Reactome:R-HSA-9033506|Reactome:R-HSA-1566979|Reactome:R-HSA-1602484|Reactome:R-HSA-1912372|Reactome:R-HSA-163798|Reactome:R-HSA-9023627|Reactome:R-HSA-3788061|Reactome:R-HSA-381500|Reactome:R-HSA-158750|Reactome:R-HSA-381135|Reactome:R-HSA-5591040|Reactome:R-HSA-8874205|Reactome:R-HSA-9668253|Reactome:R-HSA-976743|Reactome:R-HSA-381466|Reactome:R-HSA-2172405|Reactome:R-HSA-1604731|Reactome:R-HSA-140700|Reactome:R-HSA-173631|Reactome:R-HSA-158766|Reactome:R-HSA-140777|Reactome:R-HSA-159796|Reactome:R-HSA-140870|Reactome:R-HSA-114697|Reactome:R-HSA-1592297|Reactome:R-HSA-9686731|Reactome:R-HSA-1655842|Reactome:R-HSA-1181152|Reactome:R-HSA-139893|Reactome:R-HSA-166753|Reactome:R-HSA-174551|Reactome:R-HSA-8849826|Reactome:R-HSA-2534206|Reactome:R-HSA-140599|Reactome:R-HSA-173626|Reactome:R-HSA-2514823|Reactome:R-HSA-141040|Reactome:R-HSA-422051|Reactome:R-HSA-1592398|Reactome:R-HSA-5578783|Reactome:R-HSA-2471621|Reactome:R-HSA-422021|Reactome:R-HSA-2534260|Reactome:R-HSA-158333|Reactome:R-HSA-1592362|Reactome:R-HSA-2514772|Reactome:R-HSA-9023178|Reactome:R-HSA-140840|Reactome:R-HSA-6801687|Reactome:R-HSA-977615|Reactome:R-HSA-1604722|Reactome:R-HSA-9668365|Reactome:R-HSA-9023626|Reactome:R-HSA-1604690|Reactome:R-HSA-159771|Reactome:R-HSA-5210935|Reactome:R-HSA-163843|Reactome:R-HSA-5691512|Reactome:R-HSA-1604712|Reactome:R-HSA-400492|Reactome:R-HSA-159733|Reactome:R-HSA-1602488|Reactome:R-HSA-158313|Reactome:R-HSA-140664|Reactome:R-HSA-159728|Reactome:R-HSA-265301|Reactome:R-HSA-158744|Reactome:R-HSA-158419|Reactome:R-HSA-1604360|EC:3.4.21.-|Reactome:R-HSA-140736|Reactome:R-HSA-1799329|Reactome:R-HSA-158311|Reactome:R-HSA-1592371|Reactome:R-HSA-8865275|Reactome:R-HSA-3814820|Reactome:R-HSA-171288|Reactome:R-HSA-158300|Reactome:R-HSA-2471842|Reactome:R-HSA-166817|Reactome:R-HSA-158925|Reactome:R-HSA-9033530|Reactome:R-HSA-159773|Reactome:R-HSA-9686710|Reactome:R-HSA-400496|Reactome:R-HSA-158982|Reactome:R-HSA-1566962|Reactome:R-HSA-8852716|Reactome:R-HSA-173745|Reactome:R-HSA-1602458|Reactome:R-HSA-9655046|Reactome:R-HSA-1604359|Reactome:R-HSA-5210912|Reactome:R-HSA-381446|Reactome:R-HSA-1604368|Reactome:R-HSA-1604763|Reactome:R-HSA-3266557|Reactome:R-HSA-6800299|Reactome:R-HSA-8849857|Reactome:R-HSA-9666383|Reactome:R-HSA-9023633|Reactome:R-HSA-1592270|Reactome:R-HSA-141026|Reactome:R-HSA-1604752|Reactome:R-HSA-9694287|Reactome:R-HSA-2534160|Reactome:R-HSA-382061|Reactome:R-HSA-9662786									molecular_function											owl:Class	
GO:0003094	biolink:NamedThing	glomerular filtration	The process in which plasma is filtered through the glomerular membrane which consists of capillary endothelial cells, the basement membrane, and epithelial cells. The glomerular filtrate is the same as plasma except it has no significant amount of protein.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0007460	biolink:NamedThing	R8 cell fate commitment	The process in which the R8 photoreceptor commits to its cell fate. The R8 receptor contributes the central part of the rhabdomere in the basal parts of the ommatidium.	tmpzr1t_l9r_go_relaxed.owl	restriction of R8 fate											GO:0007461		biological_process											owl:Class	
GO:0045465	biolink:NamedThing	R8 cell differentiation	The process in which a relatively unspecialized cell acquires the specialized features of the R8 photoreceptor.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0048333	biolink:NamedThing	mesodermal cell differentiation	The process in which a relatively unspecialized cell acquires the specialized features of a mesoderm cell.	tmpzr1t_l9r_go_relaxed.owl	mesoderm cell differentiation													biological_process											owl:Class	
GO:0033202	biolink:NamedThing	DNA helicase complex	A protein complex that possesses DNA helicase activity.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:1900608	biolink:NamedThing	tensidol B biosynthetic process	The chemical reactions and pathways resulting in the formation of tensidol B.	tmpzr1t_l9r_go_relaxed.owl	tensidol B biosynthesis|tensidol B synthesis|tensidol B anabolism|tensidol B formation							di	2012-05-15T06:58:51Z					biological_process											owl:Class	
GO:0046595	biolink:NamedThing	establishment of pole plasm mRNA localization	Any process that results in the directed movement of mRNA to the oocyte pole plasm.	tmpzr1t_l9r_go_relaxed.owl	establishment of oocyte pole plasm mRNA localization|establishment of pole plasm mRNA localisation											GO:0048121		biological_process											owl:Class	
GO:0003040	biolink:NamedThing	excitation of vasomotor center by aortic body chemoreceptor signaling	The process in which the molecular signal from an aortic body is relayed to the vasomotor center, causing it to signal an increase arterial pressure.	tmpzr1t_l9r_go_relaxed.owl	excitation of vasomotor center by aortic body chemoreceptor signalling													biological_process											owl:Class	
GO:0000028	biolink:NamedThing	ribosomal small subunit assembly	The aggregation, arrangement and bonding together of constituent RNAs and proteins to form the small ribosomal subunit.	tmpzr1t_l9r_go_relaxed.owl	40S ribosomal subunit assembly|30S ribosomal subunit assembly													biological_process											owl:Class	
GO:0042274	biolink:NamedThing	ribosomal small subunit biogenesis	A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a small ribosomal subunit; includes transport to the sites of protein synthesis.	tmpzr1t_l9r_go_relaxed.owl	ribosomal small subunit biogenesis and assembly													biological_process											owl:Class	
GO:0048342	biolink:NamedThing	paraxial mesodermal cell differentiation	The process in which a relatively unspecialized cell acquires the specialized features of a paraxial mesoderm cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0048341	biolink:NamedThing	paraxial mesoderm formation	The process that gives rise to the paraxial mesoderm. This process pertains to the initial formation of the structure from unspecified parts.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1904726	biolink:NamedThing	regulation of replicative senescence	Any process that modulates the frequency, rate or extent of replicative senescence.	tmpzr1t_l9r_go_relaxed.owl								rph	2015-10-14T13:11:24Z					biological_process											owl:Class	
GO:0002407	biolink:NamedThing	dendritic cell chemotaxis	The movement of a dendritic cell in response to an external stimulus.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0045685	biolink:NamedThing	regulation of glial cell differentiation	Any process that modulates the frequency, rate or extent of glia cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	regulation of neuroglia differentiation|regulation of glia cell differentiation													biological_process											owl:Class	
GO:1905493	biolink:NamedThing	regulation of G-quadruplex DNA binding	Any process that modulates the frequency, rate or extent of G-quadruplex DNA binding.	tmpzr1t_l9r_go_relaxed.owl	regulation of G-quartet DNA binding|regulation of G quartet binding|regulation of G quadruplex DNA binding|regulation of G-DNA binding|regulation of quadruplex DNA binding|regulation of G quartet DNA binding|regulation of tetraplex DNA binding|regulation of G-quartet binding							ans	2016-09-26T14:53:21Z					biological_process											owl:Class	
GO:0051880	biolink:NamedThing	G-quadruplex DNA binding	Binding to G-quadruplex DNA structures, in which groups of four guanines adopt a flat, cyclic Hoogsteen hydrogen-bonding arrangement known as a guanine tetrad. The stacking of guanine tetrads results in G-quadruplex DNA structures. G-quadruplex DNA can form under physiological conditions from some G-rich sequences, such as those found in telomeres, immunoglobulin switch regions, gene promoters, fragile X repeats, and the dimerization domain in the human immunodeficiency virus (HIV) genome.	tmpzr1t_l9r_go_relaxed.owl	G-quartet DNA binding|G quartet DNA binding|G quadruplex DNA binding|quadruplex DNA binding|G quartet binding|G-DNA binding|G-quartet binding|tetraplex DNA binding													molecular_function											owl:Class	
GO:0051461	biolink:NamedThing	positive regulation of corticotropin secretion	Any process that activates or increases the frequency, rate or extent of the regulated release of corticotropin hormone from a cell.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of adrenocorticotropic hormone secretion|upregulation of adrenocorticotropin secretion|activation of adrenocorticotropin secretion|positive regulation of corticotropic hormone secretion|up-regulation of adrenocorticotropin secretion|stimulation of adrenocorticotropin secretion|positive regulation of adrenotropic hormone secretion|positive regulation of adrenocorticotropin secretion|up regulation of adrenocorticotropin secretion|positive regulation of adrenotropin secretion|positive regulation of ACTH secretion													biological_process											owl:Class	
GO:0051458	biolink:NamedThing	corticotropin secretion	The regulated release of corticotropin by a cell. Corticotropin hormone is a polypeptide hormone synthesized and secreted from corticotropes in the anterior lobe of the pituitary gland in response to corticotropin-releasing hormone (CRH) released by the hypothalamus.	tmpzr1t_l9r_go_relaxed.owl	adrenotropin secretion|adrenotropic hormone secretion|ACTH secretion|adrenocorticotropic hormone secretion|corticotropic hormone secretion|adrenocorticotropin secretion													biological_process											owl:Class	
GO:0090026	biolink:NamedThing	positive regulation of monocyte chemotaxis	Any process that increases the frequency, rate, or extent of monocyte chemotaxis.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-08-03T10:18:54Z					biological_process											owl:Class	
GO:0001997	biolink:NamedThing	positive regulation of the force of heart contraction by epinephrine-norepinephrine	Any process that increases the force with which the cardiac muscles of the heart pump blood through the circulatory system as a result of the presence of epinephrine or norepinephrine in the bloodstream or released from the nerve endings.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of heart contraction by epinephrine-norepinephrine|positive regulation of heart contraction by adrenaline-noradrenaline|increased force of heart contraction by epinephrine-norepinephrine|increased force of heart contraction by adrenaline-noradrenaline|increased inotropy by epinephrine-norepinephrine|increased strength of cardiac contraction by epinephrine-norepinephrine													biological_process											owl:Class	
GO:0003321	biolink:NamedThing	positive regulation of blood pressure by epinephrine-norepinephrine	Any process in which the force of blood traveling through the circulatory system is increased by the chemicals epinephrine and norepinephrine.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-10-29T01:52:50Z					biological_process											owl:Class	
GO:0090708	biolink:NamedThing	specification of plant organ axis polarity	The process in which the polarity of a plant organ axis is specified.	tmpzr1t_l9r_go_relaxed.owl								tb	2016-10-05T12:47:11Z					biological_process											owl:Class	
GO:0032335	biolink:NamedThing	regulation of activin secretion	Any process that modulates the frequency, rate or extent of the regulated release of activin from a cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1902033	biolink:NamedThing	regulation of hematopoietic stem cell proliferation	Any process that modulates the frequency, rate or extent of hematopoietic stem cell proliferation.	tmpzr1t_l9r_go_relaxed.owl	regulation of hemopoietic stem cell proliferation							ss	2013-04-02T05:13:19Z					biological_process											owl:Class	
GO:0071425	biolink:NamedThing	hematopoietic stem cell proliferation	The expansion of a hematopoietic stem cell population by cell division. A hematopoietic stem cell is a stem cell from which all cells of the lymphoid and myeloid lineages develop.	tmpzr1t_l9r_go_relaxed.owl	hemopoietic stem cell proliferation							mah	2009-12-16T10:22:52Z					biological_process											owl:Class	
GO:0001228	biolink:NamedThing	DNA-binding transcription activator activity, RNA polymerase II-specific	A DNA-binding transcription factor activity that activates or increases transcription of specific gene sets transcribed by RNA polymerase II.	tmpzr1t_l9r_go_relaxed.owl	RNA polymerase II transcriptional activator activity, copper ion regulated proximal promoter sequence-specific DNA binding|RNA polymerase II transcriptional activator activity, zinc ion regulated core promoter proximal region sequence-specific binding|transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding|transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding|sequence-specific distal enhancer binding RNA polymerase II transcription factor activity involved in positive regulation of transcription|proximal promoter DNA-binding transcription activator activity, RNA polymerase II-specific|distal enhancer DNA-binding transcription activator activity, RNA polymerase II-specific|zinc ion regulated core promoter proximal region sequence-specific DNA binding RNA polymerase II transcription factor activity involved in positive regulation of transcription|RNA polymerase II transcriptional activator activity, zinc ion regulated proximal promoter sequence-specific DNA binding|RNA polymerase II transcriptional activator activity, metal ion regulated proximal promoter sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|copper ion regulated core promoter proximal region sequence-specific DNA binding RNA polymerase II transcription factor activity involved in positive regulation of transcription|transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding|transcriptional activator activity, metal ion regulated sequence-specific DNA binding|RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|metal ion regulated core promoter proximal region sequence-specific DNA binding RNA polymerase II transcription factor activity involved in positive regulation of transcription|transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific DNA binding|RNA polymerase II distal enhancer sequence-specific DNA-binding transcription factor activity involved in positive regulation of transcription|metal ion regulated sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|RNA polymerase II transcriptional activator activity, metal ion regulated core promoter proximal region sequence-specific binding	https://github.com/geneontology/go-ontology/issues/16131|https://github.com/geneontology/go-ontology/issues/16534|https://github.com/geneontology/go-ontology/issues/16152|https://github.com/geneontology/go-ontology/issues/20253				For usage guidance, see comment in GO:0003700 ; DNA-binding transcription factor activity.		krc	2012-01-26T03:10:20Z			GO:0001209|GO:0001212|GO:0001077|GO:0001205|GO:0001213|GO:0001211		molecular_function											owl:Class	
GO:0086010	biolink:NamedThing	membrane depolarization during action potential	The process in which membrane potential changes in the depolarizing direction from the negative resting potential towards the positive membrane potential that will be the peak of the action potential.	tmpzr1t_l9r_go_relaxed.owl								tb	2011-11-10T08:15:05Z					biological_process											owl:Class	
GO:0072307	biolink:NamedThing	regulation of metanephric nephron tubule epithelial cell differentiation	Any process that modulates the frequency, rate or extent of metanephric nephron tubule epithelial cell differentiation.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-04-09T05:03:41Z					biological_process											owl:Class	
GO:0072257	biolink:NamedThing	metanephric nephron tubule epithelial cell differentiation	The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the metanephric nephron tubule as it progresses from its formation to the mature state.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-03-19T04:11:02Z					biological_process											owl:Class	
GO:0048314	biolink:NamedThing	embryo sac morphogenesis	The process in which the anatomical structures of the embryo sac are generated and organized. The embryo sac develops from the megaspore in heterosporous plants.	tmpzr1t_l9r_go_relaxed.owl	female gametophyte morphogenesis													biological_process											owl:Class	
GO:0009561	biolink:NamedThing	megagametogenesis	The process whose specific outcome is the progression of the embryo sac over time, from its formation as the megaspore to the mature structure. The process begins when three of the four haploid megaspores disintegrate, and the fourth undergoes mitosis giving rise to a binucleate syncytial embryo sac. The two haploid nuclei migrate to the opposite poles of the embryo sac and then undergo two rounds of mitosis generating four haploid nuclei at each pole. One nucleus from each set of four migrates to the center of the cell. Cellularization occurs, resulting in an eight-nucleate seven-celled structure. This structure contains two synergid cells and an egg cell at the micropylar end, and three antipodal cells at the other end. A binucleate endosperm mother cell is formed at the center.	tmpzr1t_l9r_go_relaxed.owl	megagametophyte nucleus division|embryo sac development from the megaspore				Wikipedia:Megagametogenesis									biological_process											owl:Class	
GO:1902005	biolink:NamedThing	regulation of proline biosynthetic process	Any process that modulates the frequency, rate or extent of proline biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of proline biosynthesis|regulation of proline formation|regulation of proline synthesis|regulation of proline anabolism							tb	2013-03-21T21:48:07Z					biological_process											owl:Class	
GO:0010984	biolink:NamedThing	regulation of lipoprotein particle clearance	Any process that modulates the rate, frequency, or extent of lipoprotein particle clearance. Lipoprotein particle clearance is the process in which a lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-06-01T12:05:12Z					biological_process											owl:Class	
GO:0007340	biolink:NamedThing	acrosome reaction	The discharge, by sperm, of a single, anterior secretory granule following the sperm's attachment to the zona pellucida of the oocyte. The process begins with the fusion of the outer acrosomal membrane with the sperm plasma membrane and ends with the exocytosis of the acrosomal contents into the zona pellucida.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Acrosome_reaction	If the release of the acrosome content occurs before the sperm reaches the zona pellucida, consider using premature acrosome loss.								biological_process											owl:Class	
GO:0033083	biolink:NamedThing	regulation of immature T cell proliferation	Any process that modulates the frequency, rate or extent of immature T cell proliferation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0033079	biolink:NamedThing	immature T cell proliferation	The expansion of an immature T cell population by cell division.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0061263	biolink:NamedThing	mesonephric glomerular mesangial cell development	The process whose specific outcome is the progression of a glomerular mesangial cell in the mesonephros over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-08-30T02:52:55Z					biological_process											owl:Class	
GO:0009832	biolink:NamedThing	plant-type cell wall biogenesis	A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cellulose and pectin-containing cell wall. An example of this is found in Arabidopsis thaliana.	tmpzr1t_l9r_go_relaxed.owl	cell wall formation|cell wall assembly|cell wall anabolism|cell wall synthesis|cell wall biosynthetic process|cellulose and pectin-containing cell wall biogenesis													biological_process											owl:Class	
GO:0014905	biolink:NamedThing	myoblast fusion involved in skeletal muscle regeneration	A process in which non-proliferating myoblasts, after migrating to the site of injury, fuse into existing damaged fibers or fuse to myotubes to form new fibers, as part of the process of skeletal muscle regeneration. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0034388	biolink:NamedThing	Pwp2p-containing subcomplex of 90S preribosome	A protein complex that forms a subcomplex of the 90S preribosome and can interact directly with the 5' External Transcribed Spacer (ETS) of the full length pre-rRNA transcript. In S. cerevisiae, it sediments at 25-30 S and is composed of Pwp2p, Dip2p, Utp21p, Utp13p, Utp18p, and Utp6p.	tmpzr1t_l9r_go_relaxed.owl	UTP-B complex|25-30 S subcomplex of 90S preribosome					Note that the term name uses Saccharomyces gene product names because no other names have yet arisen for this complex; the term nevertheless can be used for analogous complexes in other eukaryotes, and the name can be changed if better wording is found.								cellular_component											owl:Class	
GO:0044615	biolink:NamedThing	nuclear pore nuclear basket	A filamentous, cage-like assembly on the nuclear face of the nuclear pore complex (NPC). In S. cerevisiae, Mlp1p and Mlp2p are two major components of the NPC nuclear basket. In vertebrates, Tpr is a major component.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-06-20T01:31:01Z					cellular_component											owl:Class	
GO:0005884	biolink:NamedThing	actin filament	A filamentous structure formed of a two-stranded helical polymer of the protein actin and associated proteins. Actin filaments are a major component of the contractile apparatus of skeletal muscle and the microfilaments of the cytoskeleton of eukaryotic cells. The filaments, comprising polymerized globular actin molecules, appear as flexible structures with a diameter of 5-9 nm. They are organized into a variety of linear bundles, two-dimensional networks, and three dimensional gels. In the cytoskeleton they are most highly concentrated in the cortex of the cell just beneath the plasma membrane.	tmpzr1t_l9r_go_relaxed.owl	microfilament				Wikipedia:Actin|NIF_Subcellular:sao1588493326|FMA:63850									cellular_component											owl:Class	
GO:2001153	biolink:NamedThing	positive regulation of renal water transport	Any process that activates or increases the frequency, rate or extent of renal water transport.	tmpzr1t_l9r_go_relaxed.owl								yaf	2011-10-24T11:38:01Z					biological_process											owl:Class	
GO:2001167	biolink:NamedThing	negative regulation of histone H2B ubiquitination	Any process that stops, prevents or reduces the frequency, rate or extent of histone H2B ubiquitination.	tmpzr1t_l9r_go_relaxed.owl								se	2011-10-25T10:49:56Z					biological_process											owl:Class	
GO:0033523	biolink:NamedThing	histone H2B ubiquitination	The modification of histone H2B by addition of ubiquitin groups.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0046718	biolink:NamedThing	viral entry into host cell	The process that occurs after viral attachment by which a virus, or viral nucleic acid, breaches the plasma membrane or cell envelope and enters the host cell. The process ends when the viral nucleic acid is released into the host cell cytoplasm.	tmpzr1t_l9r_go_relaxed.owl	virion penetration into host cell|viral penetration|virus entry into host cell|phage translocation|entry of virus into host cell|virion penetration				VZ:936	Viral attachment to the host cell is not part of viral entry in GO because virus attachment does not always lead to viral entry: attachment can also result in the virion being carried by the host cell to another location.						GO:0019063		biological_process											owl:Class	
GO:0060028	biolink:NamedThing	convergent extension involved in axis elongation	The morphogenetic process in which an epithelium narrows along one axis and lengthens in a perpendicular axis contributing to the lengthening of the axis of an organism.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0000103	biolink:NamedThing	sulfate assimilation	The pathways by which inorganic sulfate is processed and incorporated into sulfated compounds.	tmpzr1t_l9r_go_relaxed.owl	sulphate assimilation|sulphate assimilation, phosphoadenylyl sulphate reduction by an oxidoreductase, acting on sulphur group of donors, NAD or NADP as acceptor|sulfate assimilation, phosphoadenylyl sulfate reduction by an oxidoreductase, acting on sulfur group of donors, NAD or NADP as acceptor											GO:0019378		biological_process											owl:Class	
GO:1904490	biolink:NamedThing	negative regulation of mitochondrial unfolded protein response by negative regulation of transcription from RNA polymerase II promoter	A negative regulation of transcription from RNA polymerase II promoter that results in negative regulation of mitochondrial unfolded protein response.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of mtUPR by downregulation of transcription from RNA polymerase II promoter|negative regulation of mtUPR by negative regulation of transcription from RNA polymerase II promoter, global|negative regulation of mitochondrial unfolded protein response by negative regulation of transcription from Pol II promoter|negative regulation of mtUPR by negative regulation of global transcription from Pol II promoter|negative regulation of mtUPR by negative regulation of transcription from RNA polymerase II promoter|negative regulation of mtUPR by negative regulation of transcription from Pol II promoter|negative regulation of mtUPR by downregulation of global transcription from RNA polymerase II promoter|negative regulation of mitochondrial unfolded protein response by negative regulation of transcription from RNA polymerase II promoter, global|negative regulation of mitochondrial unfolded protein response by downregulation of transcription from RNA polymerase II promoter|negative regulation of mtUPR by down-regulation of transcription from RNA polymerase II promoter|negative regulation of mitochondrial unfolded protein response by down regulation of global transcription from RNA polymerase II promoter|negative regulation of mtUPR by inhibition of transcription from RNA polymerase II promoter|negative regulation of mtUPR by down regulation of global transcription from RNA polymerase II promoter|negative regulation of mitochondrial unfolded protein response by down regulation of transcription from RNA polymerase II promoter|negative regulation of mitochondrial unfolded protein response by inhibition of global transcription from RNA polymerase II promoter|negative regulation of mtUPR by inhibition of global transcription from RNA polymerase II promoter|negative regulation of mitochondrial unfolded protein response by down-regulation of transcription from RNA polymerase II promoter|negative regulation of mitochondrial unfolded protein response by negative regulation of gene-specific transcription from RNA polymerase II promoter|negative regulation of mtUPR by down regulation of transcription from RNA polymerase II promoter|negative regulation of mtUPR by down-regulation of global transcription from RNA polymerase II promoter|negative regulation of mitochondrial unfolded protein response by negative regulation of global transcription from Pol II promoter|negative regulation of mitochondrial unfolded protein response by downregulation of global transcription from RNA polymerase II promoter|negative regulation of mtUPR by negative regulation of gene-specific transcription from RNA polymerase II promoter|negative regulation of mitochondrial unfolded protein response by inhibition of transcription from RNA polymerase II promoter|negative regulation of mitochondrial unfolded protein response by down-regulation of global transcription from RNA polymerase II promoter							kmv	2015-07-17T18:15:13Z					biological_process											owl:Class	
GO:0034514	biolink:NamedThing	mitochondrial unfolded protein response	The series of molecular signals generated as a consequence of the presence of unfolded proteins in the mitochondrial matrix; results in transcriptional upregulation of nuclear genes encoding mitochondrial stress proteins.	tmpzr1t_l9r_go_relaxed.owl	mtUPR													biological_process											owl:Class	
GO:1903647	biolink:NamedThing	negative regulation of chlorophyll catabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of chlorophyll catabolic process.	tmpzr1t_l9r_go_relaxed.owl	downregulation of chlorophyll catabolic process|inhibition of chlorophyll degradation|negative regulation of chlorophyll degradation|negative regulation of chlorophyll breakdown|down-regulation of chlorophyll catabolic process|inhibition of chlorophyll catabolism|downregulation of chlorophyll catabolism|downregulation of chlorophyll breakdown|down regulation of chlorophyll degradation|down-regulation of chlorophyll catabolism|inhibition of chlorophyll breakdown|downregulation of chlorophyll degradation|down regulation of chlorophyll catabolic process|down regulation of chlorophyll breakdown|negative regulation of chlorophyll catabolism|down-regulation of chlorophyll degradation|down-regulation of chlorophyll breakdown|inhibition of chlorophyll catabolic process|down regulation of chlorophyll catabolism							tb	2014-11-22T00:18:25Z					biological_process											owl:Class	
GO:1990200	biolink:NamedThing	SsuD-SsuE complex	A protein complex containing an alkanesulfonate monooxygenase subunit (SsuD tetramer in E.coli) and a flavin oxidoreductase subunit (SsuE dimer in E.coli). Involved in the utilization of alkanesulfonates as sulfur sources under conditions of sulfate or cysteine starvation.	tmpzr1t_l9r_go_relaxed.owl	two-component alkanesulfonate monooxygenase system							bhm	2013-10-03T12:59:26Z					cellular_component											owl:Class	
GO:0075268	biolink:NamedThing	regulation of aecium development	Any process that modulates the frequency, rate or extent of aecium development, a process in which a cuplike structure containing chains of aeciospores is formed.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0075267	biolink:NamedThing	aecium development	The process in which a cup-like structure containing chains of aeciospores is formed. This is characteristic of the rust fungus and typically, the first dikaryotic spores (aeciospores) are produced in the aecium.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1904479	biolink:NamedThing	negative regulation of intestinal absorption	Any process that stops, prevents or reduces the frequency, rate or extent of intestinal absorption.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of intestinal absorption|down regulation of intestinal absorption|downregulation of intestinal absorption|inhibition of intestinal absorption							rl	2015-07-13T15:58:54Z					biological_process											owl:Class	
GO:0050892	biolink:NamedThing	intestinal absorption	Any process in which nutrients are taken up from the contents of the intestine.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0045316	biolink:NamedThing	negative regulation of compound eye photoreceptor development	Any process that stops, prevents, or reduces the frequency, rate or extent of compound eye photoreceptor development.	tmpzr1t_l9r_go_relaxed.owl	inhibition of eye photoreceptor development|down regulation of eye photoreceptor development|downregulation of eye photoreceptor development|down-regulation of eye photoreceptor development|negative regulation of eye photoreceptor development													biological_process											owl:Class	
GO:0042051	biolink:NamedThing	compound eye photoreceptor development	The process whose specific outcome is the progression of a light-responsive receptor in the compound eye over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl	adult eye photoreceptor development													biological_process											owl:Class	
GO:0030679	biolink:NamedThing	cyanelle ribonuclease P complex	A ribonuclease P complex located in the cyanelle, where it catalyzes the 5' endonucleolytic cleavage of precursor tRNAs to yield mature tRNAs. The best characterized cyanelle ribonuclease P complex, from the alga Cyanophora paradoxa, contains a single RNA molecule that is necessary but not sufficient for catalysis, and several protein molecules.	tmpzr1t_l9r_go_relaxed.owl	cyanelle RNase P complex													cellular_component											owl:Class	
GO:0009332	biolink:NamedThing	glutamate-tRNA ligase complex	An enzyme complex that catalyzes the ligation of glutamate and tRNA(Glu) to form glutamyl-tRNA(Glu).	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0060642	biolink:NamedThing	white fat cell differentiation involved in mammary gland fat development	The process in which a preadipocyte acquires specialized features of a white adipocyte of the mammary gland. White adipocytes have cytoplasmic lipids arranged in a unique vacuole.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-05-27T05:50:56Z					biological_process											owl:Class	
GO:0042318	biolink:NamedThing	penicillin biosynthetic process	The chemical reactions and pathways resulting in the formation of any antibiotic that contains the condensed beta-lactamthiazolidine ring system.	tmpzr1t_l9r_go_relaxed.owl	penicillin biosynthesis|penicillin synthesis|penicillin anabolism|penicillin formation													biological_process											owl:Class	
GO:0097373	biolink:NamedThing	MCM core complex	A protein complex that contains Mcm4, Mcm6, and Mcm7 proteins, and possesses DNA helicase activity. In the heterohexameric MCM complex, the Mcm4/6/7 proteins form a stable core, and Mcm2, Mcm3, and Mcm5 are more peripherally associated.	tmpzr1t_l9r_go_relaxed.owl	MCM4/6/7 complex							pr	2012-09-12T10:41:42Z					cellular_component											owl:Class	
GO:1904709	biolink:NamedThing	negative regulation of granulosa cell apoptotic process	Any process that stops, prevents or reduces the frequency, rate or extent of granulosa cell apoptotic process.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of granulosa cell of ovary apoptotic process|down regulation of granulosa cell of ovary apoptosis|inhibition of granulosa cell apoptotic process|inhibition of granulosa cell of ovary apoptosis|down-regulation of granulosa cell of ovary apoptotic process|down-regulation of granulosa cell apoptosis|downregulation of granulosa cell apoptosis|down-regulation of granulosa cell apoptotic process|downregulation of granulosa cell apoptotic process|down-regulation of granulosa cell of ovary apoptosis|down regulation of granulosa cell apoptosis|inhibition of granulosa cell of ovary apoptotic process|down regulation of granulosa cell of ovary apoptotic process|inhibition of granulosa cell apoptosis|downregulation of granulosa cell of ovary apoptosis|down regulation of granulosa cell apoptotic process|negative regulation of granulosa cell apoptosis|negative regulation of granulosa cell of ovary apoptosis|downregulation of granulosa cell of ovary apoptotic process							sl	2015-10-01T16:09:45Z					biological_process											owl:Class	
GO:1905945	biolink:NamedThing	regulation of response to calcium ion	Any process that modulates the frequency, rate or extent of response to calcium ion.	tmpzr1t_l9r_go_relaxed.owl	regulation of response to Ca2+ ion							bc	2017-02-13T10:56:34Z					biological_process											owl:Class	
GO:0051592	biolink:NamedThing	response to calcium ion	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a calcium ion stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to Ca2+ ion													biological_process											owl:Class	
GO:0070645	biolink:NamedThing	Ubisch body	A small, granular structure that is found in the extracellular matrix of cell of the secretory tapetal layer that surrounds developing pollen grains. Ubisch bodies have a sporopollenin coat, are attached to the peritapetal wall, and may play a role in pollen development.	tmpzr1t_l9r_go_relaxed.owl	orbicule							mah	2009-05-11T11:35:33Z					cellular_component											owl:Class	
GO:0031012	biolink:NamedThing	extracellular matrix	A structure lying external to one or more cells, which provides structural support, biochemical or biomechanical cues for cells or tissues.	tmpzr1t_l9r_go_relaxed.owl	matrisome|proteinaceous extracellular matrix				NIF_Subcellular:nlx_subcell_20090513|Wikipedia:Extracellular_matrix							GO:0005578		cellular_component											owl:Class	
GO:0030888	biolink:NamedThing	regulation of B cell proliferation	Any process that modulates the frequency, rate or extent of B cell proliferation.	tmpzr1t_l9r_go_relaxed.owl	regulation of B-cell proliferation|regulation of B lymphocyte proliferation|regulation of B-lymphocyte proliferation													biological_process											owl:Class	
GO:0005774	biolink:NamedThing	vacuolar membrane	The lipid bilayer surrounding the vacuole and separating its contents from the cytoplasm of the cell.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:2000891	biolink:NamedThing	cellobiose metabolic process	The chemical reactions and pathways involving a cellobiose.	tmpzr1t_l9r_go_relaxed.owl	cellobiose metabolism							jl	2011-07-28T01:35:35Z					biological_process											owl:Class	
GO:0099531	biolink:NamedThing	presynaptic process involved in chemical synaptic transmission	The pathway leading to secretion of a neurotransmitter from the presynapse as part of synaptic transmission.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0001507	biolink:NamedThing	acetylcholine catabolic process in synaptic cleft	The chemical reactions and pathways resulting in the breakdown of acetylcholine that occurs in the synaptic cleft during synaptic transmission.	tmpzr1t_l9r_go_relaxed.owl	acetylcholine breakdown in synaptic cleft|acetylcholine degradation in synaptic cleft													biological_process											owl:Class	
GO:0043083	biolink:NamedThing	synaptic cleft	The narrow gap that separates the presynaptic and postsynaptic membranes, into which neurotransmitter is released.	tmpzr1t_l9r_go_relaxed.owl					NIF_Subcellular:sao243541954									cellular_component											owl:Class	
GO:1904271	biolink:NamedThing	L-proline import across plasma membrane	The directed movement of L-proline from outside of a cell, across the plasma membrane and into the cytosol.	tmpzr1t_l9r_go_relaxed.owl	L-proline import into cell							mah	2015-01-16T14:36:01Z			GO:1903809		biological_process											owl:Class	
GO:0060666	biolink:NamedThing	dichotomous subdivision of terminal units involved in salivary gland branching	The process in which a salivary epithelial cord bifurcates at its end.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-06-01T09:38:40Z					biological_process											owl:Class	
GO:0060445	biolink:NamedThing	branching involved in salivary gland morphogenesis	The process in which the branching structure of the salivary gland is generated and organized.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0021823	biolink:NamedThing	cerebral cortex tangential migration using cell-cell interactions	The process in which neurons interact with each other to promote migration along a tangential plane.	tmpzr1t_l9r_go_relaxed.owl	chain migration													biological_process											owl:Class	
GO:1990096	biolink:NamedThing	positive regulation of transcription from RNA polymerase II promoter in response to superoxide	Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a superoxide stimulus. Superoxide is the anion, oxygen-, formed by addition of one electron to dioxygen (O2) or any compound containing the superoxide anion.	tmpzr1t_l9r_go_relaxed.owl								pr	2013-05-07T12:25:34Z					biological_process											owl:Class	
GO:0071451	biolink:NamedThing	cellular response to superoxide	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a superoxide stimulus. Superoxide is the anion, oxygen-, formed by addition of one electron to dioxygen (O2) or any compound containing the superoxide anion.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-12-16T04:39:14Z					biological_process											owl:Class	
GO:0097538	biolink:NamedThing	ciliary necklace	A protein complex located on the cilium membrane in the ciliary transition zone; it is connected to the cilium axoneme via Y-shaped links.	tmpzr1t_l9r_go_relaxed.owl	cilial necklace|cilium necklace							pr	2013-12-03T16:43:41Z					cellular_component											owl:Class	
GO:1901291	biolink:NamedThing	negative regulation of double-strand break repair via single-strand annealing	Any process that stops, prevents or reduces the frequency, rate or extent of double-strand break repair via single-strand annealing.	tmpzr1t_l9r_go_relaxed.owl	inhibition of double-strand break repair via single-strand annealing|down regulation of double-strand break repair via single-strand annealing|downregulation of double-strand break repair via single-strand annealing|down-regulation of double-strand break repair via single-strand annealing							sart	2012-08-20T09:03:03Z					biological_process											owl:Class	
GO:0045002	biolink:NamedThing	double-strand break repair via single-strand annealing	Repair of a DSB made between two repeated sequences oriented in the same direction occurs primarily by the single strand annealing pathway. The ends of the break are processed by a 5' to 3' exonuclease, exposing complementary single-strand regions of the direct repeats that can anneal, resulting in a deletion of the unique DNA between the direct repeats.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1903894	biolink:NamedThing	regulation of IRE1-mediated unfolded protein response	Any process that modulates the frequency, rate or extent of the IRE1-mediated unfolded protein response.	tmpzr1t_l9r_go_relaxed.owl	regulation of UPR signaling by IRE1 stress sensor|regulation of IRE1 signaling in response to endoplasmic reticulum stress|regulation of IRE1p unfolded protein response|regulation of IRE1 signal transduction pathway|regulation of endoplasmic reticulum unfolded protein response; IRE1 signaling|regulation of IRE1alpha unfolded protein response|regulation of ERN1-mediated unfolded protein response|regulation of IRE1 branch of UPR|regulation of inositol-requiring transmembrane kinase/endonuclease signal transduction							bf	2015-02-09T10:17:46Z					biological_process											owl:Class	
GO:0009999	biolink:NamedThing	negative regulation of auditory receptor cell fate specification	Any process that restricts, stops or prevents a cell from specifying into an auditory hair cell.	tmpzr1t_l9r_go_relaxed.owl	down regulation of auditory receptor cell fate specification|down-regulation of auditory receptor cell fate specification|downregulation of auditory receptor cell fate specification|inhibition of auditory receptor cell fate specification|suppression of hair cell fate|suppression of auditory receptor cell fate|negative regulation of auditory hair cell fate specification													biological_process											owl:Class	
GO:0042667	biolink:NamedThing	auditory receptor cell fate specification	The process in which a cell becomes capable of differentiating autonomously into an auditory hair cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.	tmpzr1t_l9r_go_relaxed.owl	auditory hair cell fate specification													biological_process											owl:Class	
GO:0050788	biolink:NamedThing	sequestering of mercury	The process of binding or confining toxic mercury ions or atoms such that they are separated from sensitive components of a biological system.	tmpzr1t_l9r_go_relaxed.owl	mercury (Hg) ion sequestration|mercury (Hg2+) ion retention|sequestering of mercury (Hg) ion|mercuric ion (Hg2+) sequestering|mercury (Hg2+) ion storage|mercuric ion (Hg2+) sequestration|retention of mercury (Hg2+) ion|sequestering of mercuric ion (Hg2+)|sequestration of mercuric ion (Hg2+)|storage of mercury (Hg2+) ion|sequestration of mercury (Hg) ion|mercury (Hg) ion sequestering													biological_process											owl:Class	
GO:0050787	biolink:NamedThing	detoxification of mercury ion	Any process that reduce or remove the toxicity of mercuric ion. These include transport of mercury away from sensitive areas and to compartments or complexes whose purpose is sequestration of mercury ion and/or reduction of mercury ion (Hg[II]) to metallic mercury (Hg[0]).	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0045959	biolink:NamedThing	negative regulation of complement activation, classical pathway	Any process that stops, prevents, or reduces the frequency, rate or extent of complement activation by the classical pathway.	tmpzr1t_l9r_go_relaxed.owl	inhibition of complement activation, classical pathway|negative regulation of complement cascade, classical pathway|downregulation of complement activation, classical pathway|down-regulation of complement activation, classical pathway|down regulation of complement activation, classical pathway													biological_process											owl:Class	
GO:0006958	biolink:NamedThing	complement activation, classical pathway	Any process involved in the activation of any of the steps of the classical pathway of the complement cascade which allows for the direct killing of microbes, the disposal of immune complexes, and the regulation of other immune processes.	tmpzr1t_l9r_go_relaxed.owl	complement cascade, classical pathway													biological_process											owl:Class	
GO:1990918	biolink:NamedThing	double-strand break repair involved in meiotic recombination	The repair of double-strand breaks in DNA via homologous and nonhomologous mechanisms to reform a continuous DNA helix that contributes to reciprocal meiotic recombination.	tmpzr1t_l9r_go_relaxed.owl								al	2015-12-11T01:01:14Z					biological_process											owl:Class	
GO:1905673	biolink:NamedThing	positive regulation of lysosome organization	Any process that activates or increases the frequency, rate or extent of lysosome organization.	tmpzr1t_l9r_go_relaxed.owl	activation of lysosome organisation|up regulation of lysosome organization and biogenesis|upregulation of lysosome organization|positive regulation of lysosome organization and biogenesis|upregulation of lysosome organization and biogenesis|up-regulation of lysosome organization|activation of lysosome organization|positive regulation of lysosome organisation|up regulation of lysosome organization|up-regulation of lysosome organisation|up-regulation of lysosome organization and biogenesis|up regulation of lysosome organisation|activation of lysosome organization and biogenesis|upregulation of lysosome organisation							sl	2016-11-11T22:01:20Z					biological_process											owl:Class	
GO:0035092	biolink:NamedThing	sperm DNA condensation	The progressive compaction of the spermatid chromatin so that it reaches a level of condensation that is not compatible with nuclear activities such as transcription or DNA replication.	tmpzr1t_l9r_go_relaxed.owl	sperm chromatin condensation													biological_process											owl:Class	
GO:0007289	biolink:NamedThing	spermatid nucleus differentiation	The specialization of the spermatid nucleus during the development of a spermatid into a mature male gamete competent for fertilization.	tmpzr1t_l9r_go_relaxed.owl	spermatid nuclear differentiation					See also the Cell Ontology term 'spermatid ; CL:0000018'.								biological_process											owl:Class	
GO:0048306	biolink:NamedThing	calcium-dependent protein binding	Binding to a protein or protein complex in the presence of calcium.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0046619	biolink:NamedThing	lens placode formation involved in camera-type eye formation	Establishment and formation of the optic placode, paired ectodermal placodes that become invaginated to form the embryonic lens vesicles.	tmpzr1t_l9r_go_relaxed.owl	optic placode formation in camera-type eye|optic placode formation involved in camera-type eye formation|optic placode formation involved in camera-style eye													biological_process											owl:Class	
GO:1905435	biolink:NamedThing	regulation of histone H3-K4 trimethylation	Any process that modulates the frequency, rate or extent of histone H3-K4 trimethylation.	tmpzr1t_l9r_go_relaxed.owl								hbye	2016-09-14T13:08:55Z					biological_process											owl:Class	
GO:0080182	biolink:NamedThing	histone H3-K4 trimethylation	The modification of histone H3 by addition of three methyl groups to lysine at position 4 of the histone.	tmpzr1t_l9r_go_relaxed.owl								dhl	2011-08-10T04:18:36Z					biological_process											owl:Class	
GO:0044726	biolink:NamedThing	protection of DNA demethylation of female pronucleus	The protection of the maternal genome from DNA demethylation in the zygote following fertilization.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-10-24T14:10:36Z					biological_process											owl:Class	
GO:0044725	biolink:NamedThing	chromatin reprogramming in the zygote	The global reprogramming of epigenetic modifications in the zygote following fertilization. The paternal genome undergoes active DNA demethylation before the first cell division, while the adjacent maternal genome is protected from this process.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-10-24T13:53:28Z					biological_process											owl:Class	
GO:0032381	biolink:NamedThing	negative regulation of intracellular sterol transport	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of sterols within cells.	tmpzr1t_l9r_go_relaxed.owl	downregulation of intracellular sterol transport|down regulation of intracellular sterol transport|down-regulation of intracellular sterol transport|inhibition of intracellular sterol transport													biological_process											owl:Class	
GO:0032366	biolink:NamedThing	intracellular sterol transport	The directed movement of sterols within cells.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0010835	biolink:NamedThing	regulation of protein ADP-ribosylation	Any process that modulates the frequency, rate or extent of protein ADP-ribosylation. Protein ADP-ribosylation is the transfer, from NAD, of ADP-ribose to protein amino acids.	tmpzr1t_l9r_go_relaxed.owl	regulation of protein amino acid ADP-ribosylation													biological_process											owl:Class	
GO:0034086	biolink:NamedThing	maintenance of sister chromatid cohesion	The process in which the association between sister chromatids of a replicated chromosome is maintained as chromosomes condense, attach to the spindle in a bipolar orientation, and congress to the metaphase plate.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0014724	biolink:NamedThing	regulation of twitch skeletal muscle contraction	Any process that modulates the frequency, rate or extent of twitch skeletal muscle contraction.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0014721	biolink:NamedThing	twitch skeletal muscle contraction	A process in which force is generated within twitch skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The twitch skeletal muscle responds to neurostimulations with a contraction followed by a relaxation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0075039	biolink:NamedThing	establishment of turgor in appressorium	The process in which hydrostatic pressure is increased within the symbiont appressorium to breach the cuticle of the host. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	generation of turgor in appressorium|formation of turgor in appressorium|establishment of turgor in symbiont appressorium on or near host					Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products from the symbiont involved in this process.								biological_process											owl:Class	
GO:1902457	biolink:NamedThing	negative regulation of stomatal opening	Any process that stops, prevents or reduces the frequency, rate or extent of stomatal opening.	tmpzr1t_l9r_go_relaxed.owl	down regulation of stomatal opening|inhibition of stomatal opening|downregulation of stomatal opening|down-regulation of stomatal opening							tb	2013-10-16T22:25:22Z					biological_process											owl:Class	
GO:1990069	biolink:NamedThing	stomatal opening	The process of opening of stomata, pores in the epidermis of leaves and stems bordered by two guard cells and serving in gas exchange.	tmpzr1t_l9r_go_relaxed.owl								tb	2013-03-27T21:18:48Z					biological_process											owl:Class	
GO:0061212	biolink:NamedThing	mesonephric juxtaglomerular apparatus development	The process whose specific outcome is the progression of the juxtaglomerular apparatus in the mesonephros over time, from its formation to the mature structure. The juxtaglomerular apparatus is an anatomical structure which consists of juxtaglomerular cells, extraglomerular mesangial cells and the macula densa. The juxtaglomerular apparatus lies adjacent to the glomerulus and regulates kidney function by maintaining the blood flow to the kidney and the filtration rate.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-08-17T03:27:36Z					biological_process											owl:Class	
GO:0035340	biolink:NamedThing	inosine transport	The directed movement of the purine ribonucleoside inosine, also known as hypoxanthine riboside, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	hypoxanthine riboside transport							bf	2010-03-04T10:00:58Z					biological_process											owl:Class	
GO:0036524	biolink:NamedThing	protein deglycase activity	Catalysis of the removal of a sugar or dicarbonyl from a lysine residue of a glycated protein.	tmpzr1t_l9r_go_relaxed.owl	protein deglycating enzyme				MetaCyc:RXN-17632|MetaCyc:RXN-17634|MetaCyc:RXN-17630			bf	2016-08-04T10:23:33Z					molecular_function											owl:Class	
GO:0036525	biolink:NamedThing	protein deglycation	The removal of a sugar or dicarbonyl from a glycated protein.	tmpzr1t_l9r_go_relaxed.owl	glycated protein repair					Glycation is a non enzymatic covalent addition of a sugar or dicarbonyl (methylglyoxal, glyoxal) to a protein. Deglycation repairs the glycated amino acids.		bf	2016-08-04T10:28:54Z					biological_process											owl:Class	
GO:0045222	biolink:NamedThing	CD4 biosynthetic process	The chemical reactions and pathways resulting in the formation of CD4, a CD marker that occurs on T-helper cells and is involved in MHC class II restricted interactions.	tmpzr1t_l9r_go_relaxed.owl	CD4 formation|CD4 anabolism|CD4 synthesis|CD4 biosynthesis													biological_process											owl:Class	
GO:0048317	biolink:NamedThing	seed morphogenesis	The process in which the anatomical structures of the seed are generated and organized.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0003248	biolink:NamedThing	heart capillary growth	The increase in heart capillaries that accompanies physiological hypertrophy of cardiac muscle.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-10-13T11:53:12Z					biological_process											owl:Class	
GO:0048394	biolink:NamedThing	intermediate mesodermal cell fate determination	The process in which a cell becomes capable of differentiating autonomously into a intermediate mesoderm cell regardless of its environment; upon determination, the cell fate cannot be reversed.	tmpzr1t_l9r_go_relaxed.owl	intermediate mesoderm cell fate determination													biological_process											owl:Class	
GO:0048393	biolink:NamedThing	intermediate mesodermal cell fate commitment	The process in which the developmental fate of a cell becomes restricted such that it will develop into an intermediate mesoderm cell.	tmpzr1t_l9r_go_relaxed.owl	intermediate mesoderm cell fate commitment													biological_process											owl:Class	
GO:0044843	biolink:NamedThing	cell cycle G1/S phase transition	The cell cycle process by which a cell in G1 phase commits to S phase.	tmpzr1t_l9r_go_relaxed.owl								jl	2014-03-25T16:33:47Z					biological_process											owl:Class	
GO:0010985	biolink:NamedThing	negative regulation of lipoprotein particle clearance	Any process that decreases the rate, frequency, or extent of lipoprotein particle clearance. Lipoprotein particle clearance is the process in which a lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-06-01T12:06:59Z					biological_process											owl:Class	
GO:0045945	biolink:NamedThing	positive regulation of transcription by RNA polymerase III	Any process that activates or increases the frequency, rate or extent of transcription mediated by RNA polymerase III.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of transcription from Pol III promoter|upregulation of transcription from RNA polymerase III promoter|up-regulation of transcription from RNA polymerase III promoter|activation of transcription from RNA polymerase III promoter|stimulation of transcription from RNA polymerase III promoter|up regulation of transcription from RNA polymerase III promoter|positive regulation of transcription from RNA polymerase III promoter													biological_process											owl:Class	
GO:0006383	biolink:NamedThing	transcription by RNA polymerase III	The synthesis of RNA from a DNA template by RNA polymerase III, originating at an RNAP III promoter.	tmpzr1t_l9r_go_relaxed.owl	transcription from RNA polymerase III type 3 promoter|transcription from Pol III promoter|transcription from a RNA polymerase III hybrid type promoter|transcription from RNA polymerase III promoter|U2 snRNA transcription (S. cerevisiae)|U6 snRNA transcription (mammalian)|transcription from RNA polymerase III type 2 promoter|RNA polymerase III transcription factor activity	https://github.com/geneontology/go-ontology/issues/9617|https://github.com/geneontology/go-ontology/issues/14854						krc	2010-08-18T06:37:56Z			GO:0001009|GO:0001041|GO:0001035		biological_process											owl:Class	
GO:1990157	biolink:NamedThing	DnaA-DnaB-DnaC complex	A protein-DNA complex consisting of the helicase loading complex DnaB-DnaC bound to the DNA-bound DNA replication initiation protein DnaA. Essential for DNA replication initiation.	tmpzr1t_l9r_go_relaxed.owl								bhm	2013-08-02T11:42:27Z					cellular_component											owl:Class	
GO:1902174	biolink:NamedThing	positive regulation of keratinocyte apoptotic process	Any process that activates or increases the frequency, rate or extent of keratinocyte apoptotic process.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of keratinocyte apoptotic process|up regulation of keratinocyte apoptosis|upregulation of keratinocyte apoptotic process|positive regulation of keratinocyte apoptosis|activation of keratinocyte apoptosis|up-regulation of keratinocyte apoptosis|up regulation of keratinocyte apoptotic process|activation of keratinocyte apoptotic process|upregulation of keratinocyte apoptosis							rl	2013-05-29T14:36:21Z					biological_process											owl:Class	
GO:0097283	biolink:NamedThing	keratinocyte apoptotic process	Any apoptotic process in a keratinocyte. A keratinocyte is an epidermal cell which synthesizes keratin and undergoes a characteristic change as it moves upward from the basal layers of the epidermis to the cornified (horny) layer of the skin.	tmpzr1t_l9r_go_relaxed.owl	keratinocyte apoptosis							pr	2012-03-29T10:20:51Z					biological_process											owl:Class	
GO:0014720	biolink:NamedThing	tonic skeletal muscle contraction	A process in which force is generated within tonic skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The tonic skeletal muscle is characterized by long lasting contractile responses and high resistance to fatigue.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0060755	biolink:NamedThing	negative regulation of mast cell chemotaxis	Any process that decreases the rate, frequency or extent of mast cell chemotaxis. Mast cell chemotaxis is the movement of a mast cell in response to an external stimulus.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-06-22T02:40:58Z					biological_process											owl:Class	
GO:0032473	biolink:NamedThing	cytoplasmic side of mitochondrial outer membrane	The external (cytoplasmic) face of the mitochondrial outer membrane.	tmpzr1t_l9r_go_relaxed.owl	external side of mitochondrial outer membrane|external leaflet of mitochondrial outer membrane|external side of mitochondrial envelope|cytosolic side of mitochondrial outer membrane					In GO, 'external side' still refers to part of the membrane and does not refer to components beyond (outside of) the membrane.								cellular_component											owl:Class	
GO:1902530	biolink:NamedThing	positive regulation of protein linear polyubiquitination	Any process that activates or increases the frequency, rate or extent of protein linear polyubiquitination.	tmpzr1t_l9r_go_relaxed.owl	up regulation of M1 linkage|upregulation of protein linear polyubiquitination|up regulation of protein linear polyubiquitination|activation of protein linear polyubiquitination|positive regulation of M1 linkage|up-regulation of M1 linkage|up-regulation of protein linear polyubiquitination|activation of M1 linkage|upregulation of M1 linkage					An example is BIRC2 (UniProt ID Q13490) in PMID:21931591.		ppm	2013-12-02T10:03:18Z					biological_process											owl:Class	
GO:0097039	biolink:NamedThing	protein linear polyubiquitination	A protein ubiquitination process in which a linear polymer of ubiquitin, formed by the amino-terminal methionine (M1) of one ubiquitin molecule and by the carboxy-terminal glycine (G76) of the next, is added to a protein.	tmpzr1t_l9r_go_relaxed.owl	M1 linkage							pr	2011-04-13T01:52:51Z					biological_process											owl:Class	
GO:2000114	biolink:NamedThing	regulation of establishment of cell polarity	Any process that modulates the frequency, rate or extent of establishment of cell polarity.	tmpzr1t_l9r_go_relaxed.owl	regulation of cell polarization|regulation of bud site selection/establishment of cell polarity							dph	2010-09-16T01:22:36Z					biological_process											owl:Class	
GO:0071711	biolink:NamedThing	basement membrane organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the basement membrane.	tmpzr1t_l9r_go_relaxed.owl	basement membrane organisation					Note that this term has no relationship to 'membrane organization ; GO:0061024' because the basement membrane is not a lipid bilayer.		mah	2010-03-10T11:57:10Z					biological_process											owl:Class	
GO:1905444	biolink:NamedThing	negative regulation of clathrin coat assembly	Any process that stops, prevents or reduces the frequency, rate or extent of clathrin coat assembly.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of clathrin cage assembly|down regulation of clathrin coat assembly|down-regulation of clathrin coat assembly|downregulation of clathrin cage assembly|inhibition of clathrin coat assembly|inhibition of clathrin cage assembly|down regulation of clathrin cage assembly|down-regulation of clathrin cage assembly|downregulation of clathrin coat assembly							bf	2016-09-15T14:38:30Z					biological_process											owl:Class	
GO:0048268	biolink:NamedThing	clathrin coat assembly	The process that results in the assembly of clathrin triskelia into the ordered structure known as a clathrin cage.	tmpzr1t_l9r_go_relaxed.owl	clathrin cage assembly													biological_process											owl:Class	
GO:1905847	biolink:NamedThing	negative regulation of cellular response to oxidopamine	Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to oxidopamine.	tmpzr1t_l9r_go_relaxed.owl	down regulation of cellular response to oxidopamine|inhibition of cellular response to oxidopamine|down-regulation of cellular response to oxidopamine|downregulation of cellular response to oxidopamine							rz	2017-01-19T10:46:55Z					biological_process											owl:Class	
GO:1905842	biolink:NamedThing	cellular response to oxidopamine	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxidopamine stimulus.	tmpzr1t_l9r_go_relaxed.owl								pr	2017-01-19T09:49:12Z					biological_process											owl:Class	
GO:0001738	biolink:NamedThing	morphogenesis of a polarized epithelium	The morphogenetic process in which the anatomical structures of a polarized epithelium are generated and organized. A polarized epithelium is an epithelium where the epithelial sheet is oriented with respect to the planar axis.	tmpzr1t_l9r_go_relaxed.owl	epithelial polarization													biological_process											owl:Class	
GO:1990621	biolink:NamedThing	ESCRT IV complex	An ESCRT complex that has AAA-ATPase activity and is involved in ESCRT-mediated intralumenal vesicle formation and the final stages of cytokinesis. The complex catalyzes disassembly of the ESCRT III filament around the neck of the budding vesicle in an ATP-driven reaction, resulting in membrane scission and recycling of the ESCRT III components back to the cytosol. In yeast, it is formed by the AAA ATPase Vps4 and its cofactor Vta1.	tmpzr1t_l9r_go_relaxed.owl	VPS4A/B complex|Vps4 complex|VPS4A-VPS4B|ESCRT-IV|Vta1-Vps4 complex|Vps4-Vta1 complex|vacuolar protein sorting-associated complex							pr	2015-01-29T10:02:30Z					cellular_component											owl:Class	
GO:0044298	biolink:NamedThing	cell body membrane	The plasma membrane of a cell that bears surface projections such as axons, dendrites, cilia, or flagella, excluding the plasma membrane on cell projections.	tmpzr1t_l9r_go_relaxed.owl	cell soma membrane							jl	2010-02-05T10:39:23Z					cellular_component											owl:Class	
GO:0044297	biolink:NamedThing	cell body	The portion of a cell bearing surface projections such as axons, dendrites, cilia, or flagella that includes the nucleus, but excludes all cell projections.	tmpzr1t_l9r_go_relaxed.owl	cell soma				FBbt:00005107|Wikipedia:Cell_body|FMA:67301	Note that 'cell body' and 'cell soma' are not used in the literature for cells that lack projections, nor for some cells (e.g. yeast with mating projections) that do have projections.		jl	2010-02-05T10:37:16Z					cellular_component											owl:Class	
GO:1902864	biolink:NamedThing	negative regulation of embryonic camera-type eye development	Any process that stops, prevents or reduces the frequency, rate or extent of embryonic camera-type eye development.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of embryonic camera-type eye development|down regulation of embryonic eye development|down regulation of embryonic camera-type eye development|down-regulation of embryonic eye development|inhibition of embryonic eye development|inhibition of embryonic camera-type eye development|downregulation of embryonic camera-type eye development|downregulation of embryonic eye development|negative regulation of embryonic eye development							mr	2014-04-03T15:24:06Z					biological_process											owl:Class	
GO:0031076	biolink:NamedThing	embryonic camera-type eye development	The process occurring during the embryonic phase whose specific outcome is the progression of the eye over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl	embryonic eye development													biological_process											owl:Class	
GO:1990521	biolink:NamedThing	m7G(5')pppN diphosphatase activator activity	Binds to and increases the activity of m7G(5')pppN diphosphatase.	tmpzr1t_l9r_go_relaxed.owl								vw	2014-10-23T11:20:56Z					molecular_function											owl:Class	
GO:0061233	biolink:NamedThing	mesonephric glomerular basement membrane development	The process whose specific outcome is the progression of the mesonephric glomerular basement membrane over time, from its formation to the mature structure. The mesonephric glomerular basement membrane is the basal laminal portion of the mesonephric glomerulus which performs the actual filtration.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-08-19T02:52:18Z					biological_process											owl:Class	
GO:0106012	biolink:NamedThing	positive regulation of protein localization to medial cortex	Any process that activates or increases the frequency, rate or extent of protein localization to the medial cortex.	tmpzr1t_l9r_go_relaxed.owl								hjd	2017-04-27T17:36:17Z					biological_process											owl:Class	
GO:0071574	biolink:NamedThing	protein localization to medial cortex	A process in which a protein is transported to, or maintained in, the medial cortex.	tmpzr1t_l9r_go_relaxed.owl	protein localisation to medial cortex							mah	2010-01-26T05:17:50Z					biological_process											owl:Class	
GO:0061549	biolink:NamedThing	sympathetic ganglion development	The process whose specific outcome is the progression of a sympathetic ganglion over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl	sympathetic ganglia development							dph	2013-07-10T08:38:01Z					biological_process											owl:Class	
GO:0036411	biolink:NamedThing	H-NS-Cnu complex	A trimeric protein complex containing a H-NS homodimer and a Cnu monomer. In bacteria, this complex negatively regulates transcription of a range of genes.	tmpzr1t_l9r_go_relaxed.owl								bf	2013-08-22T10:19:24Z					cellular_component											owl:Class	
GO:1990121	biolink:NamedThing	H-NS complex	A multimer of H-NS proteins that is involved in bacterial nucleoid condensation and negative regulation of global gene expression by directly binding to promoter regions. Recognizes both structural and sequence-specific motifs in double-stranded DNA and has binding preference for bent DNA.	tmpzr1t_l9r_go_relaxed.owl	histone-like protein H-NS complex|DNA-binding protein H-NS complex							bhm	2013-06-12T10:08:31Z					cellular_component											owl:Class	
GO:0010442	biolink:NamedThing	guard cell morphogenesis	Generation and organization of the polarized cell that is capable of turgor driven movement.	tmpzr1t_l9r_go_relaxed.owl	guard cell morphogenesis during differentiation													biological_process											owl:Class	
GO:0010441	biolink:NamedThing	guard cell development	The process whose specific outcome is the progression of the guard cell over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0015663	biolink:NamedThing	nicotinamide mononucleotide transmembrane transporter activity	Enables the directed movement of nicotinamide mononucleotide into, out of or within a cell, or between cells. Nicotinamide mononucleotide is a ribonucleotide in which the nitrogenous base, nicotinamide, is in beta-n-glycosidic linkage with the c-1 position of d-ribose. It is a constituent of NAD and NADP.	tmpzr1t_l9r_go_relaxed.owl	nicotinamide mononucleotide permease activity|nicotinamide ribonucleotide transmembrane transporter activity											GO:0015664		molecular_function											owl:Class	
GO:0060535	biolink:NamedThing	trachea cartilage morphogenesis	The process in which the anatomical structures of cartilage in the trachea are generated and organized.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-04-10T09:07:48Z					biological_process											owl:Class	
GO:0060534	biolink:NamedThing	trachea cartilage development	The process whose specific outcome is the progression of the tracheal cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-04-10T09:00:18Z					biological_process											owl:Class	
GO:0071017	biolink:NamedThing	U12-type catalytic step 1 spliceosome	A spliceosomal complex that is formed by the displacement of the U11 and U4atac snRNPs from the precatalytic spliceosome; the U12, U5 and U6atac snRNPs remain associated with the mRNA. This complex, sometimes called the activated spliceosome, is the catalytically active form of the spliceosome, and includes many proteins in addition to those found in the U12, and U5 and U6atac snRNPs.	tmpzr1t_l9r_go_relaxed.owl	mammalian U12-type spliceosomal complex B*|U12-type activated spliceosome|minor catalytic step 1 spliceosome|AT-AC catalytic step 1 spliceosome|yeast U12-type spliceosomal complex A1|mammalian U12-type spliceosomal complex B2							mah	2009-07-30T12:00:35Z					cellular_component											owl:Class	
GO:0005693	biolink:NamedThing	U12 snRNP	A ribonucleoprotein complex that contains small nuclear RNA U12, a heptameric ring of Sm proteins, as well as several proteins that are unique to the U12 snRNP, most of which remain associated with the U12 snRNA both while the U12 snRNP is free or assembled into a series of spliceosomal complexes.	tmpzr1t_l9r_go_relaxed.owl	snRNP U12													cellular_component											owl:Class	
GO:0097105	biolink:NamedThing	presynaptic membrane assembly	The aggregation, arrangement and bonding together of a set of components to form a presynaptic membrane, including any proteins associated with the membrane, but excluding other cellular components. A presynaptic membrane is a  specialized area of membrane of the axon terminal that faces the plasma membrane of the neuron or muscle fiber with which the axon terminal establishes a synaptic junction.	tmpzr1t_l9r_go_relaxed.owl	pre-synaptic membrane assembly					Note that 'presynaptic membrane' in this term should not be mistaken with 'presynaptic active zone'. The latter encompasses more than the former, as it also includes the specialized cortical cytoskeletal matrix in the cell cortex of a presynaptic neuron.		pr	2011-07-27T01:30:45Z					biological_process											owl:Class	
GO:0099617	biolink:NamedThing	matrix side of mitochondrial inner membrane	The side (leaflet) of the mitochondrial inner membrane that faces the matrix.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0120265	biolink:NamedThing	negative regulation of chromosome attachment to the nuclear envelope	Any process that stops, prevents, or reduces the frequency, rate or extent of the chromosome attachment to the nuclear envelope.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of chromosome attachment to the nuclear envelope|downregulation of chromosome attachment to the nuclear envelope|inhibition of chromosome attachment to the nuclear envelope|down regulation of chromosome attachment to the nuclear envelope	https://github.com/geneontology/go-ontology/issues/20020						krc	2020-09-29T20:30:32Z					biological_process											owl:Class	
GO:0097240	biolink:NamedThing	chromosome attachment to the nuclear envelope	The process in which chromatin is anchored to the nuclear envelope.	tmpzr1t_l9r_go_relaxed.owl	attachment of chromatin to nuclear envelope							pr	2012-02-07T01:11:37Z					biological_process											owl:Class	
GO:0033622	biolink:NamedThing	integrin activation	The aggregation, arrangement and bonding together of an integrin, a heterodimeric adhesion receptor formed by the non-covalent association of particular alpha and beta subunits, that lead to the increased affinity of the integrin for its extracellular ligands.	tmpzr1t_l9r_go_relaxed.owl	integrin complex activation|integrin complex assembly													biological_process											owl:Class	
GO:0052705	biolink:NamedThing	methylhistidine N-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + N-alpha-methyl-L-histidine = S-adenosyl-L-homocysteine + N-alpha,N-alpha-dimethyl-L-histidine.	tmpzr1t_l9r_go_relaxed.owl	S-adenosyl-L-methionine:N-alpha-dimethyl-L-histidine N-alpha-methyltransferase activity|histidine-alpha-N-methyltransferase activity|methylhistidine methyltransferase activity|S-adenosyl-L-methionine:alpha-N-dimethyl-L-histidine alpha-N-methyltransferase activity							ai	2011-08-05T11:54:54Z					molecular_function											owl:Class	
GO:1903914	biolink:NamedThing	negative regulation of fusion of virus membrane with host plasma membrane	Any process that stops, prevents or reduces the frequency, rate or extent of fusion of virus membrane with host plasma membrane.	tmpzr1t_l9r_go_relaxed.owl	inhibition of viral penetration via membrane fusion|down regulation of viral entry into host cell via membrane fusion with the plasma membrane|downregulation of viral envelope fusion with host cell membrane|downregulation of viral entry into host cell via membrane fusion with the plasma membrane|down regulation of viral penetration via membrane fusion|downregulation of viral envelope fusion with host plasma membrane|down-regulation of viral-cell fusion molecule activity|downregulation of fusion of virus membrane with host plasma membrane|down regulation of viral-cell fusion molecule activity|down-regulation of viral envelope fusion with host plasma membrane|negative regulation of viral entry into host cell via membrane fusion with the plasma membrane|negative regulation of viral-cell fusion molecule activity|inhibition of fusion of virus membrane with host plasma membrane|negative regulation of viral penetration via membrane fusion|negative regulation of viral envelope fusion with host plasma membrane|inhibition of viral envelope fusion with host cell membrane|down-regulation of viral envelope fusion with host membrane|down-regulation of viral entry into host cell via membrane fusion with the plasma membrane|inhibition of viral entry into host cell via membrane fusion with the plasma membrane|downregulation of viral penetration via membrane fusion|inhibition of viral envelope fusion with host plasma membrane|down regulation of viral envelope fusion with host membrane|negative regulation of viral envelope fusion with host cell membrane|downregulation of viral envelope fusion with host membrane|down regulation of viral envelope fusion with host plasma membrane|down-regulation of fusion of virus membrane with host plasma membrane|down-regulation of viral envelope fusion with host cell membrane|negative regulation of viral envelope fusion with host membrane|down regulation of viral envelope fusion with host cell membrane|downregulation of viral-cell fusion molecule activity|down regulation of fusion of virus membrane with host plasma membrane|down-regulation of viral penetration via membrane fusion|inhibition of viral envelope fusion with host membrane|inhibition of viral-cell fusion molecule activity							als	2015-02-09T11:13:32Z					biological_process											owl:Class	
GO:0044379	biolink:NamedThing	protein localization to actin cortical patch	A process in which a protein is transported to, or maintained in, an actin cortical patch.	tmpzr1t_l9r_go_relaxed.owl	protein localisation to actin cortical patch							jl	2011-12-08T02:28:42Z					biological_process											owl:Class	
GO:0005078	biolink:NamedThing	MAP-kinase scaffold activity	The binding activity of a molecule that functions as a physical support for the assembly of a multiprotein mitogen-activated protein kinase (MAPK) complex. Binds multiple kinases of the MAPKKK cascade, and also upstream signaling proteins, permitting those molecules to function in a coordinated way. Bringing together multiple enzymes and their substrates enables the signal to be transduced quickly and efficiently.	tmpzr1t_l9r_go_relaxed.owl	MAP-kinase scaffold protein activity													molecular_function											owl:Class	
GO:0051019	biolink:NamedThing	mitogen-activated protein kinase binding	Binding to a mitogen-activated protein kinase.	tmpzr1t_l9r_go_relaxed.owl	MAPK binding|MAP kinase binding|MAP-kinase anchoring activity													molecular_function											owl:Class	
GO:0140628	biolink:NamedThing	outward rectifier potassium channel inhibitor activity	Binds to and stops, prevents, or reduces the activity of an outwardly rectifying potassium channel.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/21157						pg	2021-03-24T07:58:39Z					molecular_function											owl:Class	
GO:0015271	biolink:NamedThing	outward rectifier potassium channel activity	Enables the transmembrane transfer of a potassium ion by an outwardly-rectifying voltage-gated channel. An outwardly rectifying current-voltage relation is one where at any given driving force the outward flow of K+ ions exceeds the inward flow for the opposite driving force.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0004807	biolink:NamedThing	triose-phosphate isomerase activity	Catalysis of the reaction: D-glyceraldehyde 3-phosphate = glycerone phosphate.	tmpzr1t_l9r_go_relaxed.owl	phosphotriose isomerase activity|triosephosphate isomerase activity|triose phosphoisomerase activity|D-glyceraldehyde-3-phosphate aldose-ketose-isomerase activity|D-glyceraldehyde-3-phosphate ketol-isomerase activity|triose phosphate mutase activity|triosephosphate mutase activity				Reactome:R-HSA-70481|MetaCyc:TRIOSEPISOMERIZATION-RXN|Reactome:R-HSA-70454|RHEA:18585|KEGG_REACTION:R01015|EC:5.3.1.1									molecular_function											owl:Class	
GO:0033368	biolink:NamedThing	protease localization to mast cell secretory granule	Any process in which a protease is transported to, or maintained in, a location within a secretory granule in a mast cell.	tmpzr1t_l9r_go_relaxed.owl	protease localisation in mast cell secretory granule|protease localization in mast cell secretory granule													biological_process											owl:Class	
GO:0005290	biolink:NamedThing	L-histidine transmembrane transporter activity	Enables the transfer of L-histidine from one side of a membrane to the other. L-histidine is 2-amino-3-(1H-imidazol-4-yl)propanoic acid.	tmpzr1t_l9r_go_relaxed.owl	histidine/arginine/lysine/ornithine porter activity|L-histidine transporter activity													molecular_function											owl:Class	
GO:0014014	biolink:NamedThing	negative regulation of gliogenesis	Any process that stops, prevents, or reduces the frequency, rate or extent of gliogenesis, the formation of mature glia.	tmpzr1t_l9r_go_relaxed.owl	inhibition of gliogenesis|downregulation of gliogenesis|down-regulation of gliogenesis|down regulation of gliogenesis													biological_process											owl:Class	
GO:1902424	biolink:NamedThing	negative regulation of attachment of mitotic spindle microtubules to kinetochore	Any process that stops, prevents or reduces the frequency, rate or extent of attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of attachment of spindle microtubules to kinetochore during mitosis|inhibition of attachment of spindle microtubules to kinetochore involved in mitosis|inhibition of attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation|down-regulation of attachment of spindle microtubules to mitotic chromosome|downregulation of attachment of spindle microtubules to mitotic chromosome|down regulation of attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation|negative regulation of attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation|negative regulation of mitotic attachment of spindle microtubules to kinetochore|negative regulation of attachment of spindle microtubules to kinetochore involved in mitosis|down-regulation of attachment of spindle microtubules to kinetochore involved in mitosis|negative regulation of mitotic bipolar attachment|negative regulation of attachment of spindle microtubules to kinetochore during mitosis|down-regulation of attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation|down-regulation of mitotic bipolar attachment|inhibition of attachment of spindle microtubules to kinetochore during mitosis|downregulation of mitotic bipolar attachment|down regulation of attachment of spindle microtubules to kinetochore during mitosis|inhibition of mitotic bipolar attachment|inhibition of attachment of spindle microtubules to mitotic chromosome|down regulation of attachment of spindle microtubules to kinetochore involved in mitosis|down regulation of attachment of spindle microtubules to mitotic chromosome|downregulation of attachment of spindle microtubules to kinetochore involved in mitosis|negative regulation of attachment of spindle microtubules to mitotic chromosome|down regulation of mitotic bipolar attachment|downregulation of attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation|downregulation of attachment of spindle microtubules to kinetochore during mitosis							vw	2013-09-19T10:33:46Z					biological_process											owl:Class	
GO:0090309	biolink:NamedThing	positive regulation of DNA methylation-dependent heterochromatin assembly	Any process that increases the rate, frequency, or extent of the repression of transcription by methylation of DNA, leading to the formation of heterochromatin.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of methylation-dependent chromatin silencing							tb	2010-04-09T02:12:53Z					biological_process											owl:Class	
GO:0000809	biolink:NamedThing	cytoplasmic origin of replication recognition complex	A multisubunit complex that is located at the replication origins of a chromosome in the cytoplasm.	tmpzr1t_l9r_go_relaxed.owl	prokaryotic ORC|cytoplasmic ORC													cellular_component											owl:Class	
GO:0001680	biolink:NamedThing	tRNA 3'-terminal CCA addition	Post-transcriptional addition of the terminal 3' CCA sequence to a tRNA which does not encode this sequence within the primary transcript. CCA addition proceeds by the sequential addition of CTP, CTP, and then ATP to the 3' end of the tRNA, yielding a diphosphate with each nucleotide addition.	tmpzr1t_l9r_go_relaxed.owl	-C-C-A pyrophosphorylase activity|transfer ribonucleate adenylyltransferase activity|transfer ribonucleic adenylyl (cytidylyl) transferase activity|transfer RNA adenylyltransferase activity|ribonucleic cytidylyltransferase activity|CTP(ATP):tRNA nucleotidyltransferase activity|tRNA cytidylyltransferase activity|ATP(CTP)-tRNA nucleotidyltransferase activity|CCA-adding enzyme, tRNA adenylyltransferase, tRNA cytidylyltransferase, tRNA CCA-pyrophosphorylase activity|tRNA CCA-diphosphorylase activity|CCA-adding enzyme activity|tRNA-nucleotidyltransferase activity|tRNA adenylyl(cytidylyl)transferase activity|ribonucleic cytidylic cytidylic adenylic pyrophosphorylase activity|CCA tRNA nucleotidyltransferase activity|CTP:tRNA cytidylyltransferase activity|transfer-RNA nucleotidyltransferase activity|transfer ribonucleate adenyltransferase activity|transfer ribonucleic-terminal trinucleotide nucleotidyltransferase activity|transfer ribonucleate cytidylyltransferase activity|transfer ribonucleic acid nucleotidyl transferase activity|ATP(CTP):tRNA nucleotidyltransferase activity|transfer ribonucleate nucleotidyltransferase activity				KEGG_REACTION:R09382|MetaCyc:TRNA-CYTIDYLYLTRANSFERASE-RXN									biological_process											owl:Class	
GO:0052929	biolink:NamedThing	ATP:3'-cytidine-cytidine-tRNA adenylyltransferase activity	Catalysis of the reaction: a tRNA with a 3' CC end + ATP = a tRNA with a 3' CCA end + diphosphate.	tmpzr1t_l9r_go_relaxed.owl	ATP:3'-CC-tRNA adenylyltransferase activity|ATP:tRNA adenylyltransferase activity				RHEA:60012|KEGG_REACTION:R09386|EC:2.7.7.72									molecular_function											owl:Class	
GO:0110163	biolink:NamedThing	negative regulation of mitotic spindle elongation (spindle phase three)	Any process that stops, prevents or reduces the frequency, rate or extent of the cell cycle process in which the distance is lengthened between poles of the mitotic spindle during mitotic prophase (spindle phase three).	tmpzr1t_l9r_go_relaxed.owl								kmv	2019-08-12T15:29:43Z					biological_process											owl:Class	
GO:0048593	biolink:NamedThing	camera-type eye morphogenesis	The process in which the anatomical structures of the eye are generated and organized. The camera-type eye is an organ of sight that receives light through an aperture and focuses it through a lens, projecting it on a photoreceptor field.	tmpzr1t_l9r_go_relaxed.owl	camera-style eye morphogenesis											GO:0048595|GO:0048594		biological_process											owl:Class	
GO:0043010	biolink:NamedThing	camera-type eye development	The process whose specific outcome is the progression of the camera-type eye over time, from its formation to the mature structure. The camera-type eye is an organ of sight that receives light through an aperture and focuses it through a lens, projecting it on a photoreceptor field.	tmpzr1t_l9r_go_relaxed.owl												GO:0031075|GO:0001747		biological_process											owl:Class	
GO:0046905	biolink:NamedThing	15-cis-phytoene synthase activity	Catalysis of the reaction: 2 geranylgeranyl diphosphate -> 15-cis-phytoene + 2 diphosphate.	tmpzr1t_l9r_go_relaxed.owl	phytoene synthase activity	https://github.com/geneontology/go-ontology/issues/21165			RHEA:34479	Note that this should not be confused with 'geranylgeranyl-diphosphate geranylgeranyltransferase activity ; GO:0016767', EC:2.5.1.32. This activity is the second part of the formation of phytoene from geranylgeranyl-diphosphate, the first stage of which is catalyzed by EC:2.5.1.32.								molecular_function											owl:Class	
GO:0097400	biolink:NamedThing	interleukin-17-mediated signaling pathway	A series of molecular signals initiated by the binding of interleukin-17 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.	tmpzr1t_l9r_go_relaxed.owl	IL-17-mediated signalling pathway|interleukin-17-mediated signalling pathway|IL-17-mediated signaling pathway							pr	2012-10-23T13:30:03Z					biological_process											owl:Class	
GO:0008705	biolink:NamedThing	methionine synthase activity	Catalysis of the reaction: (6S)-5-methyl-5,6,7,8-tetrahydrofolate + L-homocysteine = (6S)-5,6,7,8-tetrahydrofolate + L-methionine.	tmpzr1t_l9r_go_relaxed.owl	tetrahydrofolate methyltransferase activity|5-methyltetrahydrofolate--homocysteine transmethylase activity|B12 N(5)-methyltetrahydrofolate homocysteine methyltransferase activity|B12 N5-methyltetrahydrofolate homocysteine methyltransferase activity|methionine synthase (cobalamin-dependent) activity|N5-methyltetrahydrofolic-homocysteine vitamin B12 transmethylase activity|vitamin B12 methyltransferase activity|N5-methyltetrahydrofolate-homocysteine cobalamin methyltransferase activity|MetH|tetrahydropteroylglutamic methyltransferase activity|N(5)-methyltetrahydrofolic--homocysteine vitamin B12 transmethylase activity|N(5)-methyltetrahydrofolate--homocysteine cobalamin methyltransferase activity|tetrahydropteroylglutamate methyltransferase activity|5-methyltetrahydrofolate-homocysteine S-methyltransferase activity|N5-methyltetrahydrofolate methyltransferase activity|N(5)-methyltetrahydrofolate methyltransferase activity|methyltetrahydrofolate--homocysteine vitamin B12 methyltransferase activity|5-methyltetrahydrofolate:L-homocysteine S-methyltransferase activity|5-methyltetrahydrofolate--homocysteine S-methyltransferase activity|cobalamin-dependent methionine synthase activity|N-methyltetrahydrofolate:L-homocysteine methyltransferase activity				Reactome:R-HSA-3149539|KEGG_REACTION:R00946|RHEA:11172|Reactome:R-HSA-174374|EC:2.1.1.13|MetaCyc:HOMOCYSMETB12-RXN									molecular_function											owl:Class	
GO:0009086	biolink:NamedThing	methionine biosynthetic process	The chemical reactions and pathways resulting in the formation of methionine (2-amino-4-(methylthio)butanoic acid), a sulfur-containing, essential amino acid found in peptide linkage in proteins.	tmpzr1t_l9r_go_relaxed.owl	methionine synthesis|methionine biosynthesis|methionine formation|methionine anabolism													biological_process											owl:Class	
GO:0032952	biolink:NamedThing	regulation of (1->3)-beta-D-glucan metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving (1->3)-beta-D-glucans.	tmpzr1t_l9r_go_relaxed.owl	regulation of (1->3)-beta-D-glucan metabolism|regulation of 1,3-beta-glucan metabolic process|regulation of 1,3-beta-D-glucan metabolic process|regulation of 1,3-beta-glucan metabolism													biological_process											owl:Class	
GO:0006074	biolink:NamedThing	(1->3)-beta-D-glucan metabolic process	The chemical reactions and pathways involving (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds.	tmpzr1t_l9r_go_relaxed.owl	1,3-beta-D-glucan metabolism|1,3-beta-glucan metabolic process|beta-1,3 glucan metabolism|1,3-beta-D-glucan metabolic process|beta-1,3 glucan metabolic process													biological_process											owl:Class	
GO:1903516	biolink:NamedThing	regulation of single strand break repair	Any process that modulates the frequency, rate or extent of single strand break repair.	tmpzr1t_l9r_go_relaxed.owl								rl	2014-10-06T10:58:52Z					biological_process											owl:Class	
GO:0000012	biolink:NamedThing	single strand break repair	The repair of single strand breaks in DNA. Repair of such breaks is mediated by the same enzyme systems as are used in base excision repair.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1905949	biolink:NamedThing	negative regulation of calcium ion import across plasma membrane	Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion import across plasma membrane.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of calcium ion import across plasma membrane|down regulation of calcium ion import across plasma membrane|downregulation of calcium ion import across plasma membrane|inhibition of calcium ion import across plasma membrane					An example of this is PPP3CA in human (Q08209) in PMID:17640527 (inferred from direct assay).		bhm	2017-02-17T09:42:30Z					biological_process											owl:Class	
GO:0098703	biolink:NamedThing	calcium ion import across plasma membrane	The directed movement of calcium ions from outside of a cell, across the plasma membrane and into the cytosol.	tmpzr1t_l9r_go_relaxed.owl	calcium ion import into cell|calcium ion uptake into cell							mah	2013-02-07T13:07:59Z			GO:1990035		biological_process											owl:Class	
GO:0034774	biolink:NamedThing	secretory granule lumen	The volume enclosed by the membrane of a secretory granule.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0051209	biolink:NamedThing	release of sequestered calcium ion into cytosol	The process in which calcium ions sequestered in the endoplasmic reticulum, Golgi apparatus or mitochondria are released into the cytosolic compartment.	tmpzr1t_l9r_go_relaxed.owl	cytosolic release of sequestered calcium ion (Ca2+)|cytoplasmic release of sequestered calcium ion (Ca2+)|release of sequestered calcium ion into cytoplasm|calcium ion (Ca2+) mobilization|cytoplasmic release of stored calcium ion (Ca2+)|release of stored calcium ion (Ca2+) into cytoplasm|cytosolic release of stored calcium ion (Ca2+)|release of stored calcium ion (Ca2+)|release of stored calcium ion (Ca2+) into cytosol|calcium mobilization|release of sequestered calcium ion (Ca2+)													biological_process											owl:Class	
GO:0032656	biolink:NamedThing	regulation of interleukin-13 production	Any process that modulates the frequency, rate, or extent of interleukin-13 production.	tmpzr1t_l9r_go_relaxed.owl	regulation of interleukin-13 secretion|regulation of IL-13 production|regulation of interleukin-13 biosynthetic process											GO:2000665|GO:0045366		biological_process											owl:Class	
GO:0040018	biolink:NamedThing	positive regulation of multicellular organism growth	Any process that activates or increases the frequency, rate or extent of growth of an organism to reach its usual body size.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of body size|positive regulation of body growth													biological_process											owl:Class	
GO:0035264	biolink:NamedThing	multicellular organism growth	The increase in size or mass of an entire multicellular organism, as opposed to cell growth.	tmpzr1t_l9r_go_relaxed.owl	body growth													biological_process											owl:Class	
GO:0044870	biolink:NamedThing	modulation by host of viral glycoprotein metabolic process	A process in which a host organism modulates the frequency, rate or extent of viral glycoprotein metabolic process.	tmpzr1t_l9r_go_relaxed.owl								jl	2014-09-18T14:26:19Z					biological_process											owl:Class	
GO:2000082	biolink:NamedThing	regulation of L-ascorbic acid biosynthetic process	Any process that modulates the frequency, rate or extent of L-ascorbic acid biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of vitamin C biosynthesis|regulation of L-ascorbic acid anabolism|regulation of vitamin C biosynthetic process|regulation of ascorbate biosynthetic process|regulation of ascorbate biosynthesis|regulation of L-ascorbic acid biosynthesis|regulation of L-ascorbic acid synthesis|regulation of L-ascorbic acid formation							tb	2010-08-27T11:26:16Z					biological_process											owl:Class	
GO:0019853	biolink:NamedThing	L-ascorbic acid biosynthetic process	The chemical reactions and pathways resulting in the formation of L-ascorbic acid; L-ascorbic acid ionizes to give L-ascorbate, (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate, which is required as a cofactor in the oxidation of prolyl residues to hydroxyprolyl, and other reactions.	tmpzr1t_l9r_go_relaxed.owl	L-ascorbic acid anabolism|L-ascorbic acid formation|ascorbate biosynthesis|L-ascorbic acid synthesis|vitamin C biosynthesis|L-ascorbic acid biosynthesis|vitamin C biosynthetic process|ascorbate biosynthetic process				MetaCyc:PWY-882									biological_process											owl:Class	
GO:0006368	biolink:NamedThing	transcription elongation from RNA polymerase II promoter	The extension of an RNA molecule after transcription initiation and promoter clearance at an RNA polymerase II promoter by the addition of ribonucleotides catalyzed by RNA polymerase II.	tmpzr1t_l9r_go_relaxed.owl	RNA elongation from Pol II promoter|RNA polymerase II transcription elongation factor activity													biological_process											owl:Class	
GO:0032750	biolink:NamedThing	positive regulation of interleukin-26 production	Any process that activates or increases the frequency, rate, or extent of interleukin-26 production.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of IL-26 production|up-regulation of interleukin-26 production|up regulation of interleukin-26 production|stimulation of interleukin-26 production|upregulation of interleukin-26 production|positive regulation of interleukin-26 biosynthetic process|activation of interleukin-26 production											GO:0045538		biological_process											owl:Class	
GO:0032630	biolink:NamedThing	interleukin-26 production	The appearance of interleukin-26 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	tmpzr1t_l9r_go_relaxed.owl	AK155 secretion|interleukin-26 biosynthesis|interleukin-26 formation|interleukin-26 anabolism|interleukin-26 biosynthetic process|interleukin-26 secretion|IL-26 production|interleukin-26 synthesis											GO:0045526|GO:0072624		biological_process											owl:Class	
GO:0034492	biolink:NamedThing	hydrogenosome lumen	The volume enclosed by the hydrogenosome membrane.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0042566	biolink:NamedThing	hydrogenosome	A spherical, membrane-bounded organelle found in some anaerobic protozoa, which participates in ATP and molecular hydrogen formation.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Hydrogenosome									cellular_component											owl:Class	
GO:0075035	biolink:NamedThing	appressorium maturation	The process in which specialized features of the symbiont appressorium are acquired post initiation, to aid in infection of the host. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	maturation of appressorium on or near host|appressorium maturation on or near host|maturation of symbiont appressorium on or near host													biological_process											owl:Class	
GO:0009099	biolink:NamedThing	valine biosynthetic process	The chemical reactions and pathways resulting in the formation of valine, 2-amino-3-methylbutanoic acid.	tmpzr1t_l9r_go_relaxed.owl	valine formation|valine anabolism|valine biosynthesis|valine synthesis				MetaCyc:VALSYN-PWY									biological_process											owl:Class	
GO:0052655	biolink:NamedThing	L-valine transaminase activity	Catalysis of the reaction: 2-oxoglutarate + L-valine = 3-methyl-2-oxobutanoic acid + L-glutamatic acid.	tmpzr1t_l9r_go_relaxed.owl	L-valine aminotransferase activity				EC:2.6.1.42|MetaCyc:BRANCHED-CHAINAMINOTRANSFERVAL-RXN|KEGG_REACTION:R01214|RHEA:24813									molecular_function											owl:Class	
GO:0048839	biolink:NamedThing	inner ear development	The process whose specific outcome is the progression of the inner ear over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0061725	biolink:NamedThing	cytosolic lipolysis	The chemical reactions and pathways resulting in the breakdown of lipid droplets and hydrolysis of stored triglycerides occurring through the orchestrated activation of cytosolic lipases.	tmpzr1t_l9r_go_relaxed.owl								dph	2015-07-08T13:42:15Z					biological_process											owl:Class	
GO:0060479	biolink:NamedThing	lung cell differentiation	The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features of a mature cell found in the lung. Differentiation includes the processes involved in commitment of a cell to a specific fate.	tmpzr1t_l9r_go_relaxed.owl	pulmonary cell differentiation													biological_process											owl:Class	
GO:1903106	biolink:NamedThing	positive regulation of insulin receptor signaling pathway involved in determination of adult lifespan	Any process that activates or increases the frequency, rate or extent of insulin receptor signaling pathway involved in determination of adult lifespan.	tmpzr1t_l9r_go_relaxed.owl	activation of insulin receptor signaling pathway involved in determination of adult lifespan|up regulation of insulin receptor signaling pathway of determination of adult lifespan|positive regulation of insulin receptor signaling pathway of determination of adult lifespan|activation of daf-2 receptor signaling pathway of determination of adult lifespan|up-regulation of insulin receptor signaling pathway of determination of adult lifespan|upregulation of daf-2 receptor signaling pathway of determination of adult lifespan|upregulation of insulin receptor signalling pathway of determination of adult lifespan|positive regulation of insulin receptor signalling pathway of determination of adult lifespan|up-regulation of daf-2 receptor signaling pathway of determination of adult lifespan|activation of insulin receptor signaling pathway of determination of adult lifespan|up regulation of insulin receptor signaling pathway involved in determination of adult lifespan|up-regulation of insulin receptor signaling pathway involved in determination of adult lifespan|activation of insulin receptor signalling pathway of determination of adult lifespan|upregulation of insulin receptor signaling pathway involved in determination of adult lifespan|positive regulation of daf-2 receptor signaling pathway of determination of adult lifespan|up regulation of daf-2 receptor signaling pathway of determination of adult lifespan|upregulation of insulin receptor signaling pathway of determination of adult lifespan|up regulation of insulin receptor signalling pathway of determination of adult lifespan|up-regulation of insulin receptor signalling pathway of determination of adult lifespan							kmv	2014-06-05T20:56:19Z					biological_process											owl:Class	
GO:1901047	biolink:NamedThing	insulin receptor signaling pathway involved in determination of adult lifespan	The series of molecular signals generated as a consequence of the insulin receptor binding to insulin that controls viability and duration in the adult phase of the life-cycle.	tmpzr1t_l9r_go_relaxed.owl	daf-2 receptor signaling pathway of determination of adult lifespan|insulin receptor signaling pathway of determination of adult lifespan|insulin receptor signalling pathway of determination of adult lifespan							kmv	2012-06-27T06:55:18Z					biological_process											owl:Class	
GO:0070616	biolink:NamedThing	regulation of thiamine diphosphate biosynthetic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of thiamine diphosphate.	tmpzr1t_l9r_go_relaxed.owl	regulation of thiamine diphosphate biosynthesis|regulation of thiamin diphosphate biosynthetic process|regulation of thiamine diphosphate formation|regulation of thiamine diphosphate synthesis|regulation of thiamine diphosphate anabolism							mah	2009-04-29T03:37:35Z					biological_process											owl:Class	
GO:0009229	biolink:NamedThing	thiamine diphosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of thiamine diphosphate, a derivative of thiamine (vitamin B1) which acts as a coenzyme in a range of processes including the Krebs cycle.	tmpzr1t_l9r_go_relaxed.owl	thiamine diphosphate formation|thiamine pyrophosphate biosynthesis|TPP biosynthetic process|thiamine pyrophosphate biosynthetic process|thiamine diphosphate synthesis|TPP biosynthesis|thiamine diphosphate anabolism|thiamin diphosphate biosynthetic process|thiamin pyrophosphate biosynthesis|thiamine diphosphate biosynthesis|thiamin pyrophosphate biosynthetic process													biological_process											owl:Class	
GO:0016346	biolink:NamedThing	male meiotic chromosome movement towards spindle pole	The directed movement of chromosomes in the center of the spindle towards the spindle poles, mediated by the shortening of microtubules attached to the chromosomes, during male meiosis.	tmpzr1t_l9r_go_relaxed.owl	male meiotic chromosome movement|chromosome movement towards spindle pole during male meiosis|male meiotic chromosome movement to spindle pole													biological_process											owl:Class	
GO:0099166	biolink:NamedThing	intrinsic component of postsynaptic specialization membrane of symmetric synapse	The component of the postsynaptic specialization membrane of a symmetric synapse consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.	tmpzr1t_l9r_go_relaxed.owl	intrinsic to postsynaptic specialization membrane of symmetric synapse							dos	2017-09-10T11:56:47Z					cellular_component											owl:Class	
GO:0099164	biolink:NamedThing	postsynaptic specialization membrane of symmetric synapse	The membrane component of the postsynaptic specialization of a symmetic synapse. This is the region of the postsynaptic membrane in which the population of neurotransmitter receptors involved in synaptic transmission are concentrated.	tmpzr1t_l9r_go_relaxed.owl								dos	2017-09-10T11:50:44Z					cellular_component											owl:Class	
GO:2000411	biolink:NamedThing	negative regulation of thymocyte migration	Any process that stops, prevents or reduces the frequency, rate or extent of thymocyte migration.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of immature T lymphocyte migration|negative regulation of thymic lymphocyte migration|negative regulation of immature T-cell migration|negative regulation of immature T cell migration|negative regulation of immature T-lymphocyte migration							mah	2011-02-23T01:34:01Z					biological_process											owl:Class	
GO:0072679	biolink:NamedThing	thymocyte migration	The movement of a thymocyte through distinct intrathymic niches (e.g. medulla, cortex), where it receives a unique set of developmental cues required for T-cell development.	tmpzr1t_l9r_go_relaxed.owl	immature T lymphocyte migration|immature T-cell migration|immature T cell migration|thymic lymphocyte migration|immature T-lymphocyte migration							mah	2011-02-22T03:47:51Z					biological_process											owl:Class	
GO:0010228	biolink:NamedThing	vegetative to reproductive phase transition of meristem	The process involved in transforming a meristem that produces vegetative structures, such as leaves, into a meristem that produces reproductive structures, such as a flower or an inflorescence.	tmpzr1t_l9r_go_relaxed.owl	flowering|floral evocation|transition from vegetative to reproductive phase													biological_process											owl:Class	
GO:0038007	biolink:NamedThing	netrin-activated signaling pathway	A series of molecular events initiated by the binding of a netrin protein to a receptor on the surface of the target cell, and ending with regulation of a downstream cellular process, e.g. transcription. Netrins can act as chemoattractant signals for some cells and chemorepellent signals for others. Netrins also have roles outside of cell and axon guidance.	tmpzr1t_l9r_go_relaxed.owl	netrin-activated signal transduction pathway|netrin-activated signalling pathway|netrin signaling pathway|netrin-mediated signaling pathway							bf	2011-06-10T02:24:59Z					biological_process											owl:Class	
GO:0002777	biolink:NamedThing	antimicrobial peptide biosynthetic process	The chemical reactions and pathways resulting in the formation of an antimicrobial peptide. Such peptides may have protective properties against bacteria, fungi, viruses, or protozoa.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0060531	biolink:NamedThing	neuroendocrine cell differentiation involved in prostate gland acinus development	The process in which relatively unspecialized cells acquires specialized structural and functions of a neuroendocrine cell of the prostate gland acinus.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0021571	biolink:NamedThing	rhombomere 5 development	The process whose specific outcome is the progression of rhombomere 5 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0000388	biolink:NamedThing	spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)	Rearrangement of the pre-catalytic spliceosome containing U4 (or U4atac) and U1 (or U11) snRNPs to unpair U4 (or U4atac) from U6 (or U6atac) and release it from the spliceosomal complex along with U1 (or U11).	tmpzr1t_l9r_go_relaxed.owl	spliceosomal B2 complex biosynthesis|spliceosomal B2 complex formation|U12-type spliceosome conformational change to release U4atac and U11|U2-type spliceosome conformational change to release U4 and U1|3'-splice site cleavage, exon ligation|spliceosomal A1 complex biosynthesis|spliceosomal A1 complex formation					Note that this step represents formation of the A1 complex (yeast) or the B2 complex (mammalian).						GO:0000397|GO:0000396		biological_process											owl:Class	
GO:0045719	biolink:NamedThing	negative regulation of glycogen biosynthetic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glycogen.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of glycogen biosynthesis|negative regulation of glycogen synthesis|negative regulation of glycogen formation|downregulation of glycogen biosynthetic process|down regulation of glycogen biosynthetic process|inhibition of glycogen biosynthetic process|negative regulation of glycogen anabolism|down-regulation of glycogen biosynthetic process													biological_process											owl:Class	
GO:0005978	biolink:NamedThing	glycogen biosynthetic process	The chemical reactions and pathways resulting in the formation of glycogen, a polydisperse, highly branched glucan composed of chains of D-glucose residues.	tmpzr1t_l9r_go_relaxed.owl	glycogen biosynthesis|glycogen anabolism|glycogen synthesis|glycogen formation				MetaCyc:GLYCOGENSYNTH-PWY									biological_process											owl:Class	
GO:0009310	biolink:NamedThing	amine catabolic process	The chemical reactions and pathways resulting in the breakdown of any organic compound that is weakly basic in character and contains an amino or a substituted amino group. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom.	tmpzr1t_l9r_go_relaxed.owl	amine catabolism|amine degradation|amine breakdown													biological_process											owl:Class	
GO:0061632	biolink:NamedThing	RNA lariat debranching enzyme activator activity	Increases the activity of an enzyme that catalyzes the hydrolysis of branched RNA structures that contain vicinal 2'-5'- and 3'-5'-phosphodiester bonds at a branch point nucleotide.	tmpzr1t_l9r_go_relaxed.owl								dph	2014-06-17T10:07:31Z					molecular_function											owl:Class	
GO:0008419	biolink:NamedThing	RNA lariat debranching enzyme activity	Catalysis of the hydrolysis of branched RNA structures that contain vicinal 2'-5'- and 3'-5'-phosphodiester bonds at a branch point nucleotide.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0045261	biolink:NamedThing	proton-transporting ATP synthase complex, catalytic core F(1)	The sector of a hydrogen-transporting ATP synthase complex in which the catalytic activity resides; it comprises the catalytic core and central stalk, and is peripherally associated with a membrane, such as the plasma membrane or the mitochondrial inner membrane, when the entire ATP synthase is assembled.	tmpzr1t_l9r_go_relaxed.owl	hydrogen-transporting ATP synthase, F1 sector													cellular_component											owl:Class	
GO:1902274	biolink:NamedThing	positive regulation of (R)-carnitine transmembrane transport	Any process that activates or increases the frequency, rate or extent of (R)-carnitine transmembrane transport.	tmpzr1t_l9r_go_relaxed.owl	activation of (R)-carnitine transmembrane transport|upregulation of (R)-carnitine transmembrane transport|up-regulation of (R)-carnitine transmembrane transport|up regulation of (R)-carnitine transmembrane transport							mcc	2013-07-01T13:13:22Z					biological_process											owl:Class	
GO:1902270	biolink:NamedThing	(R)-carnitine transmembrane transport	The process in which (R)-carnitine is transported across a membrane.	tmpzr1t_l9r_go_relaxed.owl								mcc	2013-06-28T21:57:39Z					biological_process											owl:Class	
GO:0080009	biolink:NamedThing	mRNA methylation	The posttranscriptional addition of methyl groups to specific residues in an mRNA molecule.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0075045	biolink:NamedThing	regulation of formation by symbiont of haustorium for nutrient acquisition from host	Any process that modulates the frequency, rate or extent of symbiont haustorium formation for nutrient acquisition from host. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl						Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products from the symbiont involved in this process.								biological_process											owl:Class	
GO:0052094	biolink:NamedThing	formation of haustorium for nutrient acquisition	The assembly of a haustorium, a projection from a symbiotic cell or tissue that penetrates the host's tissues for the purpose of obtaining nutrients. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	formation by organism of haustorium for nutrient acquisition from host|formation by organism of haustoria for nutrient acquisition from host|formation by symbiont of haustorium for nutrient acquisition from host	https://github.com/geneontology/go-ontology/issues/20305												biological_process											owl:Class	
GO:1905446	biolink:NamedThing	regulation of mitochondrial ATP synthesis coupled electron transport	Any process that modulates the frequency, rate or extent of mitochondrial ATP synthesis coupled electron transport.	tmpzr1t_l9r_go_relaxed.owl	regulation of mitochondrial electron transport|regulation of organelle ATP synthesis coupled electron transport							dph	2016-09-15T18:57:58Z					biological_process											owl:Class	
GO:0042775	biolink:NamedThing	mitochondrial ATP synthesis coupled electron transport	The transfer of electrons through a series of electron donors and acceptors, generating energy that is ultimately used for synthesis of ATP, as it occurs in the mitochondrial inner membrane or chloroplast thylakoid membrane.	tmpzr1t_l9r_go_relaxed.owl	organelle ATP synthesis coupled electron transport|mitochondrial electron transport													biological_process											owl:Class	
GO:1905760	biolink:NamedThing	post-anaphase array microtubule end	Any microtubule end that is part of a post-anaphase array microtubule.	tmpzr1t_l9r_go_relaxed.owl	microtubule end of microtubule of post-anaphase microtubule array|microtubule end of post-anaphase array microtubule|microtubule end of neurotubule of post-anaphase array|microtubule end of microtubuli of post-anaphase microtubule array|microtubule end of neurotubule of post-anaphase microtubule array|microtubule end of microtubuli of post-anaphase array|microtubule end of microtubulus of PAA|microtubule end of neurotubule of PAA|microtubule end of microtubulus of post-anaphase microtubule array|microtubule end of microtubuli of PAA|microtubule end of microtubule of PAA|microtubule end of microtubulus of post-anaphase array|microtubule end of microtubule of post-anaphase array							dos	2016-12-12T19:38:32Z					cellular_component											owl:Class	
GO:0048796	biolink:NamedThing	swim bladder maturation	A developmental process, independent of morphogenetic (shape) change, that is required for a swim bladder to attain its fully functional state. The swim bladder is used by some fishes to maintain buoyancy and may function in addition as a sound producing organ, a sound receptor, and a respiratory organ.	tmpzr1t_l9r_go_relaxed.owl	gas bladder maturation													biological_process											owl:Class	
GO:1903146	biolink:NamedThing	regulation of autophagy of mitochondrion	Any process that modulates the frequency, rate or extent of mitochondrion degradation by an autophagic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of mitochondrion degradation							bf	2014-07-09T08:23:51Z					biological_process											owl:Class	
GO:0000422	biolink:NamedThing	autophagy of mitochondrion	The autophagic process in which mitochondria are delivered to a type of vacuole and degraded in response to changing cellular conditions.	tmpzr1t_l9r_go_relaxed.owl	mitochondrion autophagy|mitophagy				Wikipedia:Autophagy_(cellular)#Selective_autophagy|Wikipedia:Mitophagy									biological_process											owl:Class	
GO:0090676	biolink:NamedThing	calcium ion transmembrane transport via low voltage-gated calcium channel	A process in which a calcium ion is transported from one side of a membrane to the other by means of a low voltage-gated calcium channel.	tmpzr1t_l9r_go_relaxed.owl	generation of T-type calcium current							tb	2016-03-23T10:15:23Z					biological_process											owl:Class	
GO:0008332	biolink:NamedThing	low voltage-gated calcium channel activity	Enables the transmembrane transfer of a calcium ion by a low voltage-gated channel. A low voltage-gated channel is a channel whose open state is dependent on low voltage across the membrane in which it is embedded.	tmpzr1t_l9r_go_relaxed.owl	low voltage-dependent calcium channel activity|T-type calcium channel|low voltage gated calcium channel activity													molecular_function											owl:Class	
GO:0048668	biolink:NamedThing	collateral sprouting	The process in which outgrowths develop from the shafts of existing axons.	tmpzr1t_l9r_go_relaxed.owl	axon branching													biological_process											owl:Class	
GO:0046545	biolink:NamedThing	development of primary female sexual characteristics	The process whose specific outcome is the progression of the primary female sexual characteristics over time, from their formation to the mature structure. The primary female sexual characteristics are the ovaries, and they develop in response to sex hormone secretion.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:2001216	biolink:NamedThing	negative regulation of hydroxymethylglutaryl-CoA reductase (NADPH) activity	Any process that stops, prevents or reduces the frequency, rate or extent of hydroxymethylglutaryl-CoA reductase (NADPH) activity.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of HMG-CoA reductase activity|negative regulation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase activity							bf	2011-11-16T11:34:17Z					biological_process											owl:Class	
GO:0070111	biolink:NamedThing	organellar chromatophore	A bacteroid-containing symbiosome in which the bacterial component is a genetically highly reduced cyanobacterium that is photosynthetically active and incapable of an independent existence outside its host. The chromatophore functions as a photosynthetic organelle, and has been found and characterized in the amoeba Paulinella chromatophora.	tmpzr1t_l9r_go_relaxed.owl	Paulinella-type chromatophore													cellular_component											owl:Class	
GO:0021656	biolink:NamedThing	rhombomere 2 structural organization	The process that contributes to creating the structural organization of rhombomere 2. This process pertains to the physical shaping of a rudimentary structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.	tmpzr1t_l9r_go_relaxed.owl	rhombomere 2 structural organisation													biological_process											owl:Class	
GO:0021655	biolink:NamedThing	rhombomere 2 morphogenesis	The process in which the anatomical structure of rhombomere 2 is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0055009	biolink:NamedThing	atrial cardiac muscle tissue morphogenesis	The process in which the anatomical structure of cardiac atrium muscle is generated and organized.	tmpzr1t_l9r_go_relaxed.owl	atrial myocardium morphogenesis|cardiac atrium muscle morphogenesis|atrial heart muscle morphogenesis													biological_process											owl:Class	
GO:0003209	biolink:NamedThing	cardiac atrium morphogenesis	The process in which the cardiac atrium is generated and organized. A cardiac atrium receives blood from a vein and pumps it to a cardiac ventricle.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-10-13T09:39:44Z					biological_process											owl:Class	
GO:1903067	biolink:NamedThing	negative regulation of protein localization to cell tip	Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cell tip.	tmpzr1t_l9r_go_relaxed.owl	downregulation of protein localisation to cell tip|down regulation of protein localization to cell tip|downregulation of protein localization to cell tip|inhibition of protein localisation to cell tip|down-regulation of protein localisation to cell tip|down regulation of protein localisation to cell tip|inhibition of protein localization to cell tip|negative regulation of protein localisation to cell tip|down-regulation of protein localization to cell tip							vw	2014-05-28T15:48:48Z					biological_process											owl:Class	
GO:1990151	biolink:NamedThing	protein localization to cell tip	A process in which a protein is transported to, or maintained in, a location at the cell tip.	tmpzr1t_l9r_go_relaxed.owl	protein localisation to cell tip							mah	2013-07-31T14:56:40Z					biological_process											owl:Class	
GO:0035711	biolink:NamedThing	T-helper 1 cell activation	The change in morphology and behavior of a T-helper 1 cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.	tmpzr1t_l9r_go_relaxed.owl	Th1 cell activation							bf	2011-03-02T03:05:08Z					biological_process											owl:Class	
GO:0120141	biolink:NamedThing	regulation of ecdysone receptor-mediated signaling pathway	Any process that modulates the frequency, rate or extent of the activity of any ecdysone receptor-mediated signaling pathway.	tmpzr1t_l9r_go_relaxed.owl								krc	2018-03-22T17:10:29Z					biological_process											owl:Class	
GO:0035076	biolink:NamedThing	ecdysone receptor-mediated signaling pathway	The series of molecular signals generated by ecdysone binding to the ecdysone receptor complex.	tmpzr1t_l9r_go_relaxed.owl	ecdysone receptor-mediated signalling pathway													biological_process											owl:Class	
GO:0001916	biolink:NamedThing	positive regulation of T cell mediated cytotoxicity	Any process that activates or increases the frequency, rate or extent of T cell mediated cytotoxicity.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of T cell mediated cell death|positive regulation of T cell mediated cytolysis|positive regulation of T-cell mediated cytolysis|positive regulation of T cell mediated apoptosis|upregulation of T cell mediated cytotoxicity|positive regulation of T-cell mediated cytotoxicity|positive regulation of T lymphocyte mediated cytotoxicity|positive regulation of T cell mediated cell killing|up-regulation of T cell mediated cytotoxicity|positive regulation of T-cell mediated cell killing|activation of T cell mediated cytotoxicity|up regulation of T cell mediated cytotoxicity|positive regulation of T-cell mediated apoptosis|positive regulation of T-cell mediated cell death|positive regulation of T-lymphocyte mediated cytotoxicity|stimulation of T cell mediated cytotoxicity													biological_process											owl:Class	
GO:0021696	biolink:NamedThing	cerebellar cortex morphogenesis	The process in which the anatomical structure of the cranial nerves are generated and organized. The cerebellar cortex is a thin mantle of gray matter that covers the surface of each cerebral hemisphere. It has a characteristic morphology with convolutions (gyri) and crevices (sulci) that have specific functions. Six layers of nerve cells and the nerve pathways that connect them comprise the cerebellar cortex. Together, these regions are responsible for the processes of conscious thought, perception, emotion and memory as well as advanced motor function.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1900507	biolink:NamedThing	negative regulation of iron-sulfur-molybdenum cofactor assembly	Any process that stops, prevents or reduces the frequency, rate or extent of iron-sulfur-molybdenum cofactor assembly.	tmpzr1t_l9r_go_relaxed.owl	down regulation of iron molybdenum cofactor biosynthetic process|negative regulation of iron molybdenum cofactor biosynthesis|downregulation of FeMoco biosynthetic process|downregulation of iron-sulfur-molybdenum cofactor assembly|negative regulation of FeMoco assembly|down-regulation of FeMoco assembly|downregulation of iron molybdenum cofactor biosynthesis|downregulation of FeMoco assembly|negative regulation of iron molybdenum cofactor assembly|inhibition of FeMoco biosynthetic process|inhibition of iron molybdenum cofactor assembly|down-regulation of iron molybdenum cofactor biosynthetic process|down regulation of FeMoco assembly|down-regulation of FeMoco biosynthetic process|down-regulation of iron molybdenum cofactor biosynthesis|down regulation of FeMoco biosynthetic process|down-regulation of iron molybdenum cofactor assembly|negative regulation of FeMoco biosynthetic process|down regulation of iron molybdenum cofactor assembly|down-regulation of iron-sulfur-molybdenum cofactor assembly|inhibition of FeMoco assembly|down regulation of iron molybdenum cofactor biosynthesis|downregulation of iron molybdenum cofactor biosynthetic process|inhibition of iron-sulfur-molybdenum cofactor assembly|inhibition of iron molybdenum cofactor biosynthesis|down regulation of iron-sulfur-molybdenum cofactor assembly|downregulation of iron molybdenum cofactor assembly|negative regulation of iron molybdenum cofactor biosynthetic process|inhibition of iron molybdenum cofactor biosynthetic process							tt	2012-05-02T04:02:27Z					biological_process											owl:Class	
GO:0044593	biolink:NamedThing	iron-sulfur-molybdenum cofactor assembly	The chemical reactions and pathways resulting in the formation of iron-sulfur-molybdenum cofactor, the cofactor located at the active site of the molybdenum nitrogenase.	tmpzr1t_l9r_go_relaxed.owl	iron molybdenum cofactor assembly|iron molybdenum cofactor biosynthetic process|iron molybdenum cofactor biosynthesis|FeMoco biosynthetic process|FeMoco assembly							jl	2012-04-26T04:01:53Z					biological_process											owl:Class	
GO:0071706	biolink:NamedThing	tumor necrosis factor superfamily cytokine production	The appearance of any member of the TNF superfamily due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	tmpzr1t_l9r_go_relaxed.owl	TNF superfamily production|TNFSF cytokine production					Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.		mah	2010-03-09T02:40:35Z					biological_process											owl:Class	
GO:0005740	biolink:NamedThing	mitochondrial envelope	The double lipid bilayer enclosing the mitochondrion and separating its contents from the cell cytoplasm; includes the intermembrane space.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:1905445	biolink:NamedThing	positive regulation of clathrin coat assembly	Any process that activates or increases the frequency, rate or extent of clathrin coat assembly.	tmpzr1t_l9r_go_relaxed.owl	upregulation of clathrin coat assembly|up-regulation of clathrin coat assembly|up regulation of clathrin coat assembly|activation of clathrin cage assembly|activation of clathrin coat assembly|up regulation of clathrin cage assembly|up-regulation of clathrin cage assembly|positive regulation of clathrin cage assembly|upregulation of clathrin cage assembly							bf	2016-09-15T14:38:38Z					biological_process											owl:Class	
GO:0110039	biolink:NamedThing	positive regulation of nematode male tail tip morphogenesis	Any process that activates or increases the frequency, rate or extent of nematode male tail tip morphogenesis.	tmpzr1t_l9r_go_relaxed.owl								kmv	2017-07-24T20:32:58Z					biological_process											owl:Class	
GO:0045138	biolink:NamedThing	nematode male tail tip morphogenesis	The process in which the anatomical structure of the adult male tail tip is generated and organized. In some species of rhabitid nematodes, the male tail tip undergoes a morphological change such that the most posterior hypodermal cells in the tail (hyp8-11 in C. elegans) fuse and retract anteriorly, changing the shape of the tail from a pointed, tapered cone, or spike, to a rounded, blunt dome.	tmpzr1t_l9r_go_relaxed.owl	male tail tip morphogenesis|tail tip morphogenesis|male tail morphogenesis													biological_process											owl:Class	
GO:0002072	biolink:NamedThing	optic cup morphogenesis involved in camera-type eye development	The invagination of the optic vesicle to form two-walled indentations, the optic cups, that will go on to form the retina. This process begins with the optic vesicle becoming a two-walled structure and its subsequent shape changes. It does not include the fate commitment of cells to become the pigmented retina and the neural retina. An example of this process is found in Mus musculus.	tmpzr1t_l9r_go_relaxed.owl	optic cup morphogenesis involved in camera-style eye development													biological_process											owl:Class	
GO:0060900	biolink:NamedThing	embryonic camera-type eye formation	The developmental process pertaining to the initial formation of a camera-type eye from unspecified neurectoderm. This process begins with the differentiation of cells that form the optic field and ends when the optic cup has attained its shape.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-08-13T02:26:54Z					biological_process											owl:Class	
GO:0061888	biolink:NamedThing	regulation of astrocyte activation	Any process that modulates the frequency, rate or extent of astrocyte activation.	tmpzr1t_l9r_go_relaxed.owl								dph	2017-06-01T22:26:29Z					biological_process											owl:Class	
GO:0048143	biolink:NamedThing	astrocyte activation	A change in morphology and behavior of an astrocyte resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0098576	biolink:NamedThing	lumenal side of membrane	Any side (leaflet) of a membrane that faces the lumen of an organelle.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0035745	biolink:NamedThing	T-helper 2 cell cytokine production	Any process that contributes to cytokine production by a T-helper 2 cell.	tmpzr1t_l9r_go_relaxed.owl	Th2 cell cytokine production					Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.		bf	2011-03-17T02:23:32Z					biological_process											owl:Class	
GO:1901609	biolink:NamedThing	negative regulation of vesicle transport along microtubule	Any process that stops, prevents or reduces the frequency, rate or extent of vesicle transport along microtubule.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of vesicle transport along microtubule|down regulation of vesicle transport along microtubule|downregulation of vesicle transport along microtubule|down-regulation of microtubule-based vesicle localization|inhibition of vesicle transport along microtubule|inhibition of microtubule-based vesicle localization|down regulation of microtubule-based vesicle localization|negative regulation of microtubule-based vesicle localization|downregulation of microtubule-based vesicle localization							hjd	2012-11-08T21:49:48Z					biological_process											owl:Class	
GO:0001897	biolink:NamedThing	cytolysis by symbiont of host cells	The killing by an organism of a cell in its host organism by means of the rupture of cell membranes and the loss of cytoplasm. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	cytolysis by organism of host cells|pathogenesis													biological_process											owl:Class	
GO:0052025	biolink:NamedThing	modification by symbiont of host cell membrane	The process in which an organism effects a change in the structure or function of a host cellular membrane. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0008218	biolink:NamedThing	bioluminescence	The production of light by certain enzyme-catalyzed reactions in cells.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Bioluminescence									biological_process											owl:Class	
GO:1902957	biolink:NamedThing	negative regulation of mitochondrial electron transport, NADH to ubiquinone	Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrial electron transport, NADH to ubiquinone.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of oxidative phosphorylation, NADH to ubiquinone|inhibition of complex I (NADH to ubiquinone)|negative regulation of complex I (NADH to ubiquinone)|down-regulation of complex I (NADH to ubiquinone)|downregulation of mitochondrial electron transport, NADH to ubiquinone|down regulation of oxidative phosphorylation, NADH to ubiquinone|negative regulation of oxidative phosphorylation, NADH to ubiquinone|down regulation of mitochondrial electron transport, NADH to ubiquinone|inhibition of mitochondrial electron transport, NADH to ubiquinone|downregulation of complex I (NADH to ubiquinone)|down regulation of complex I (NADH to ubiquinone)|down-regulation of mitochondrial electron transport, NADH to ubiquinone|inhibition of oxidative phosphorylation, NADH to ubiquinone|downregulation of oxidative phosphorylation, NADH to ubiquinone							dph	2014-05-02T15:30:18Z					biological_process											owl:Class	
GO:0006120	biolink:NamedThing	mitochondrial electron transport, NADH to ubiquinone	The transfer of electrons from NADH to ubiquinone that occurs during oxidative phosphorylation.	tmpzr1t_l9r_go_relaxed.owl	complex I (NADH to ubiquinone)|oxidative phosphorylation, NADH to ubiquinone													biological_process											owl:Class	
GO:0030282	biolink:NamedThing	bone mineralization	The deposition of hydroxyapatite, a form of calcium phosphate with the formula Ca10(PO4)6(OH)2, in bone tissue.	tmpzr1t_l9r_go_relaxed.owl	bone calcification													biological_process											owl:Class	
GO:0002790	biolink:NamedThing	peptide secretion	The controlled release of a peptide from a cell or a tissue.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0009321	biolink:NamedThing	alkyl hydroperoxide reductase complex	An enzyme complex, usually a homodimer, which directly reduces cellular levels of organic hydroperoxides.	tmpzr1t_l9r_go_relaxed.owl						See also the molecular function term 'alkyl hydroperoxide reductase activity ; GO:0008785'.								cellular_component											owl:Class	
GO:1900569	biolink:NamedThing	chanoclavine-I aldehyde biosynthetic process	The chemical reactions and pathways resulting in the formation of chanoclavine-I aldehyde.	tmpzr1t_l9r_go_relaxed.owl	chanoclavine-I aldehyde synthesis|chanoclavine-I aldehyde biosynthesis|chanoclavine-I aldehyde anabolism|chanoclavine-I aldehyde formation							di	2012-05-15T06:31:28Z					biological_process											owl:Class	
GO:1902354	biolink:NamedThing	blood vessel endothelial cell delamination involved in blood vessel lumen ensheathment	Any blood vessel endothelial cell delamination that is involved in blood vessel lumen ensheathment.	tmpzr1t_l9r_go_relaxed.owl								pr	2013-08-14T10:22:00Z					biological_process											owl:Class	
GO:0097496	biolink:NamedThing	blood vessel lumen ensheathment	A blood vessel lumenization process that occurs by blood vessel endothelial cells delaminating and aligning along the inner surface of an existing luminal space, extending the open ended lumen, and joining to other blood vessels to form a complete blood vessel.	tmpzr1t_l9r_go_relaxed.owl								pr	2013-08-12T13:46:45Z					biological_process											owl:Class	
GO:0090372	biolink:NamedThing	positive regulation of glycerol transport	Any process that increases the rate, frequency, or extent of the directed movement of glycerol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl								tb	2010-07-12T11:30:22Z					biological_process											owl:Class	
GO:0015793	biolink:NamedThing	glycerol transport	The directed movement of glycerol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Glycerol is 1,2,3-propanetriol, a sweet, hygroscopic, viscous liquid, widely distributed in nature as a constituent of many lipids.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0035310	biolink:NamedThing	notum cell fate specification	The process in which a cell in the larval wing imaginal disc becomes capable of differentiating autonomously into a notum cell, if left in its normal environment.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0035309	biolink:NamedThing	wing and notum subfield formation	The regionalization process that subdivides the wing imaginal disc into the wing and notum (body wall) subfields, thus determining whether cells ultimately differentiate wing or notum-specific structures.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0008029	biolink:NamedThing	pentraxin receptor activity	Combining with a pentraxin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	pentaxin receptor					Note that pentraxins include such proteins as serum amyloid P component (SAP) and C-reactive protein (CRP).								molecular_function											owl:Class	
GO:0001864	biolink:NamedThing	pentraxin binding	Binding to a pentraxin, a member of a family of inflammatory proteins with a radially symmetric arrangement of five identical, noncovalently linked chains in a pentagonal array.	tmpzr1t_l9r_go_relaxed.owl						Note that pentraxins include such proteins as serum amyloid P component (SAP) and C-reactive protein (CRP).								molecular_function											owl:Class	
GO:1903282	biolink:NamedThing	regulation of glutathione peroxidase activity	Any process that modulates the frequency, rate or extent of glutathione peroxidase activity.	tmpzr1t_l9r_go_relaxed.owl	regulation of reduced glutathione peroxidase activity|regulation of GSH peroxidase activity|regulation of non-selenium glutathione peroxidase activity|regulation of selenium-glutathione peroxidase activity|regulation of glutathione:hydrogen-peroxide oxidoreductase activity							bf	2014-08-11T13:14:13Z					biological_process											owl:Class	
GO:0045188	biolink:NamedThing	regulation of circadian sleep/wake cycle, non-REM sleep	Any process that modulates the frequency, rate or extent of non-rapid eye movement sleep.	tmpzr1t_l9r_go_relaxed.owl	regulation of non-REM sleep													biological_process											owl:Class	
GO:0042748	biolink:NamedThing	circadian sleep/wake cycle, non-REM sleep	All sleep stages in the circadian sleep/wake cycle other than REM sleep. These stages are characterized by a slowing of brain waves and other physiological functions.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0042320	biolink:NamedThing	regulation of circadian sleep/wake cycle, REM sleep	Any process that modulates the frequency, rate or extent of rapid eye movement (REM) sleep.	tmpzr1t_l9r_go_relaxed.owl	regulation of REM sleep													biological_process											owl:Class	
GO:0042747	biolink:NamedThing	circadian sleep/wake cycle, REM sleep	A stage in the circadian sleep cycle during which dreams occur and the body undergoes marked changes including rapid eye movement, loss of reflexes, and increased pulse rate and brain activity.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0032249	biolink:NamedThing	regulation of adenosine transport	Any process that modulates the frequency, rate or extent of the directed movement of adenosine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0032238	biolink:NamedThing	adenosine transport	The directed movement of adenosine, adenine riboside, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0033369	biolink:NamedThing	establishment of protein localization to mast cell secretory granule	The directed movement of a protein to a location within a secretory granule in a mast cell.	tmpzr1t_l9r_go_relaxed.owl	establishment of protein localization in mast cell secretory granule|establishment of protein localisation in mast cell secretory granule													biological_process											owl:Class	
GO:0033367	biolink:NamedThing	protein localization to mast cell secretory granule	A process in which a protein is transported to, or maintained in, a location within a secretory granule in a mast cell.	tmpzr1t_l9r_go_relaxed.owl	protein localisation in mast cell secretory granule|protein localization in mast cell secretory granule													biological_process											owl:Class	
GO:0062155	biolink:NamedThing	curli secretion complex	A protein-containing complex that serves as a channel for the secretion of curli. Curli are a fibers that serve as a major component of the extracellular matrix of pellicle biofilms.	tmpzr1t_l9r_go_relaxed.owl								dph	2019-09-20T14:05:13Z					cellular_component											owl:Class	
GO:1904625	biolink:NamedThing	negative regulation of glycine secretion, neurotransmission	Any process that stops, prevents or reduces the frequency, rate or extent of glycine secretion, neurotransmission.	tmpzr1t_l9r_go_relaxed.owl	downregulation of glycine secretion, neurotransmission|down regulation of glycine secretion, neurotransmission|down-regulation of glycine secretion, neurotransmission|inhibition of glycine secretion, neurotransmission							hjd	2015-08-27T20:03:44Z					biological_process											owl:Class	
GO:0061537	biolink:NamedThing	glycine secretion, neurotransmission	The controlled release of glycine by a cell, in which glycine acts as a neurotransmitter.	tmpzr1t_l9r_go_relaxed.owl								dph	2013-06-21T16:19:02Z					biological_process											owl:Class	
GO:0007409	biolink:NamedThing	axonogenesis	De novo generation of a long process of a neuron, including the terminal branched region. Refers to the morphogenesis or creation of shape or form of the developing axon, which carries efferent (outgoing) action potentials from the cell body towards target cells.	tmpzr1t_l9r_go_relaxed.owl	axon morphogenesis|neuron long process generation|axon growth					Note that 'axonogenesis' differs from 'axon development' in that the latter also covers other processes, such as axon regeneration (regrowth after loss or damage, not necessarily of the whole axon).						GO:0007410		biological_process											owl:Class	
GO:1904504	biolink:NamedThing	positive regulation of lipophagy	Any process that activates or increases the frequency, rate or extent of lipophagy.	tmpzr1t_l9r_go_relaxed.owl	upregulation of lipophagy|activation of lipophagy|up regulation of lipophagy|up-regulation of lipophagy							dph	2015-07-24T11:37:24Z					biological_process											owl:Class	
GO:0061724	biolink:NamedThing	lipophagy	The selective autophagy process in which lipid droplets are delivered to the vacuole and degraded in response to changing cellular conditions.	tmpzr1t_l9r_go_relaxed.owl								dph	2015-07-08T13:38:19Z					biological_process											owl:Class	
GO:0072042	biolink:NamedThing	regulation of mesenchymal stem cell proliferation involved in nephron morphogenesis	Any process that modulates the frequency, rate or extent of mesenchymal stem cell proliferation and contributes to the shaping of a nephron.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-01-25T03:11:26Z					biological_process											owl:Class	
GO:0033039	biolink:NamedThing	salty taste receptor activity	Combining with soluble salty compounds to initiate a change in cell activity. These receptors are responsible for the sense of salty taste.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1903922	biolink:NamedThing	negative regulation of protein processing in phagocytic vesicle	Any process that stops, prevents or reduces the frequency, rate or extent of protein processing in phagocytic vesicle.	tmpzr1t_l9r_go_relaxed.owl	down regulation of peptidolysis during protein maturation in phagosome|down-regulation of protein maturation by peptide bond cleavage in phagocytic vesicle|down-regulation of peptidolysis during protein maturation in phagosome|negative regulation of protein maturation by proteolysis in phagosome|negative regulation of protein maturation by peptide bond cleavage in phagocytic vesicle|down regulation of protein maturation by proteolysis in phagosome|downregulation of protein maturation by peptide bond cleavage in phagocytic vesicle|downregulation of protein maturation by peptide bond hydrolysis in phagocytic vesicle|down regulation of protein maturation by peptide bond hydrolysis in phagocytic vesicle|down regulation of peptidolysis during protein maturation in phagocytic vesicle|inhibition of protein processing in phagocytic vesicle|negative regulation of protein maturation by proteolysis in phagocytic vesicle|negative regulation of protein processing in phagosome|downregulation of protein maturation by peptide bond cleavage in phagosome|down regulation of protein processing in phagocytic vesicle|downregulation of protein maturation by proteolysis in phagocytic vesicle|down regulation of protein processing in phagosome|inhibition of protein maturation by proteolysis in phagocytic vesicle|negative regulation of peptidolysis during protein maturation in phagocytic vesicle|down regulation of protein maturation by proteolysis in phagocytic vesicle|downregulation of protein processing in phagosome|down regulation of protein maturation by peptide bond cleavage in phagosome|inhibition of protein maturation by peptide bond cleavage in phagosome|inhibition of protein processing in phagosome|inhibition of protein maturation by peptide bond hydrolysis in phagocytic vesicle|downregulation of peptidolysis during protein maturation in phagosome|down regulation of protein maturation by peptide bond cleavage in phagocytic vesicle|down regulation of protein maturation by peptide bond hydrolysis in phagosome|inhibition of peptidolysis during protein maturation in phagocytic vesicle|down-regulation of protein maturation by peptide bond hydrolysis in phagocytic vesicle|negative regulation of protein maturation by peptide bond cleavage in phagosome|down-regulation of protein processing in phagocytic vesicle|negative regulation of protein maturation by peptide bond hydrolysis in phagosome|inhibition of protein maturation by peptide bond cleavage in phagocytic vesicle|down-regulation of peptidolysis during protein maturation in phagocytic vesicle|downregulation of protein processing in phagocytic vesicle|inhibition of peptidolysis during protein maturation in phagosome|inhibition of protein maturation by peptide bond hydrolysis in phagosome|down-regulation of protein maturation by peptide bond cleavage in phagosome|downregulation of protein maturation by peptide bond hydrolysis in phagosome|inhibition of protein maturation by proteolysis in phagosome|negative regulation of peptidolysis during protein maturation in phagosome|negative regulation of protein maturation by peptide bond hydrolysis in phagocytic vesicle|downregulation of protein maturation by proteolysis in phagosome|down-regulation of protein maturation by proteolysis in phagocytic vesicle|down-regulation of protein maturation by peptide bond hydrolysis in phagosome|down-regulation of protein processing in phagosome|down-regulation of protein maturation by proteolysis in phagosome|downregulation of peptidolysis during protein maturation in phagocytic vesicle							als	2015-02-10T11:17:05Z					biological_process											owl:Class	
GO:0031947	biolink:NamedThing	negative regulation of glucocorticoid biosynthetic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glucocorticoids.	tmpzr1t_l9r_go_relaxed.owl	downregulation of glucocorticoid biosynthetic process|down regulation of glucocorticoid biosynthetic process|inhibition of glucocorticoid biosynthetic process|down-regulation of glucocorticoid biosynthetic process													biological_process											owl:Class	
GO:0006704	biolink:NamedThing	glucocorticoid biosynthetic process	The chemical reactions and pathways resulting in the formation of glucocorticoids, hormonal C21 corticosteroids synthesized from cholesterol.	tmpzr1t_l9r_go_relaxed.owl	glucocorticoid biosynthesis|glucocorticoid synthesis|glucocorticoid anabolism|glucocorticoid formation													biological_process											owl:Class	
GO:0001947	biolink:NamedThing	heart looping	The tube morphogenesis process in which the primitive heart tube loops asymmetrically. This looping brings the primitive heart chambers into alignment preceding their future integration. Heart looping begins with dextral-looping and ends when the main regional divisions of the mature heart and primordium of the great arterial trunks become established preceeding septation.	tmpzr1t_l9r_go_relaxed.owl	cardiac looping													biological_process											owl:Class	
GO:0072071	biolink:NamedThing	kidney interstitial fibroblast differentiation	The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the interstitial fibroblast of the kidney as it progresses from its formation to the mature state.	tmpzr1t_l9r_go_relaxed.owl	kidney interstitial cell differentiation							mah	2010-01-25T04:34:31Z					biological_process											owl:Class	
GO:0048703	biolink:NamedThing	embryonic viscerocranium morphogenesis	The process in which the anatomical structures of the viscerocranium are generated and organized during the embryonic phase. The viscerocranium is the part of the skull comprising the facial bones.	tmpzr1t_l9r_go_relaxed.owl	embryonic pharyngeal skeleton morphogenesis													biological_process											owl:Class	
GO:0005850	biolink:NamedThing	eukaryotic translation initiation factor 2 complex	Complex of three heterogeneous polypeptide chains, that form a ternary complex with initiator methionyl-tRNA and GTP. This ternary complex binds to free 40S subunit, which subsequently binds the 5' end of mRNA.	tmpzr1t_l9r_go_relaxed.owl	eIF2|eIF-2				Wikipedia:EIF-2									cellular_component											owl:Class	
GO:0090726	biolink:NamedThing	cortical dynamic polarity patch	A region of the cell cortex that contains a higher concentration of growth polarity factors than the surrounding cortex and that changes position over time. An example is found in fission yeast cells during early mating, in which the GTPase Cdc42 dynamically to discrete zones within the cortex prior to shmoo formation.	tmpzr1t_l9r_go_relaxed.owl	dynamic polarity patch at the cell cortex							tb	2016-11-22T16:17:02Z					cellular_component											owl:Class	
GO:0005938	biolink:NamedThing	cell cortex	The region of a cell that lies just beneath the plasma membrane and often, but not always, contains a network of actin filaments and associated proteins.	tmpzr1t_l9r_go_relaxed.owl	peripheral cytoplasm|cell periphery				Wikipedia:Cell_cortex									cellular_component											owl:Class	
GO:0022626	biolink:NamedThing	cytosolic ribosome	A ribosome located in the cytosol.	tmpzr1t_l9r_go_relaxed.owl	80S ribosome|70S ribosome											GO:0009281|GO:0030871|GO:0005830		cellular_component											owl:Class	
GO:0007065	biolink:NamedThing	male meiosis sister chromatid cohesion	The joining of the sister chromatids of a replicated chromosome along the entire length of the chromosome that occurs during meiosis in a male.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1904791	biolink:NamedThing	negative regulation of shelterin complex assembly	Any process that stops, prevents or reduces the frequency, rate or extent of shelterin complex assembly.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of shelterin complex formation|inhibition of shelterin complex formation|down regulation of telosome assembly|down-regulation of Pot1 complex assembly|down regulation of shelterin complex formation|down regulation of Pot1-Tpz1 complex assembly|downregulation of telosome assembly|down-regulation of telosome assembly|down regulation of Pot1 complex assembly|downregulation of shelterin complex formation|inhibition of telosome assembly|inhibition of Pot1 complex assembly|downregulation of Pot1-Tpz1 complex assembly|inhibition of Pot1-Tpz1 complex assembly|downregulation of Pot1 complex assembly|negative regulation of shelterin complex formation|negative regulation of Pot1 complex assembly|down-regulation of Pot1-Tpz1 complex assembly|negative regulation of Pot1-Tpz1 complex assembly|negative regulation of telosome assembly							nc	2015-11-06T16:13:11Z					biological_process											owl:Class	
GO:1902524	biolink:NamedThing	positive regulation of protein K48-linked ubiquitination	Any process that activates or increases the frequency, rate or extent of protein K48-linked ubiquitination.	tmpzr1t_l9r_go_relaxed.owl	upregulation of protein K48-linked ubiquitination|positive regulation of protein K48-linked polyubiquitination|up-regulation of protein K48-linked polyubiquitination|activation of protein K48-linked ubiquitination|up regulation of protein K48-linked polyubiquitination|activation of protein K48-linked polyubiquitination|upregulation of protein K48-linked polyubiquitination|up-regulation of protein K48-linked ubiquitination|up regulation of protein K48-linked ubiquitination					An example is BIRC2 (UniProt ID Q13490) in PMID:21931591.		ppm	2013-12-02T09:56:40Z					biological_process											owl:Class	
GO:0070936	biolink:NamedThing	protein K48-linked ubiquitination	A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 48 of the ubiquitin monomers, is added to a protein. K48-linked ubiquitination targets the substrate protein for degradation.	tmpzr1t_l9r_go_relaxed.owl	protein K48-linked polyubiquitination							mah	2009-09-21T03:25:27Z					biological_process											owl:Class	
GO:0015647	biolink:NamedThing	peptidoglycan transmembrane transporter activity	Enables the transfer of peptidoglycans, a class of glycoconjugates found in bacterial cell walls, from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	murein transporter activity													molecular_function											owl:Class	
GO:0120266	biolink:NamedThing	positive regulation of chromosome attachment to the nuclear envelope	Any process that activates or increases the frequency, rate or extent of the chromosome attachment to the nuclear envelope.	tmpzr1t_l9r_go_relaxed.owl	activation of chromosome attachment to the nuclear envelope|stimulation of chromosome attachment to the nuclear envelope|up-regulation of chromosome attachment to the nuclear envelope|upregulation of chromosome attachment to the nuclear envelope|up regulation of chromosome attachment to the nuclear envelope	https://github.com/geneontology/go-ontology/issues/20020						krc	2020-09-29T20:30:45Z					biological_process											owl:Class	
GO:0097540	biolink:NamedThing	axonemal central pair	Part of the axoneme consisting of the inner two microtubule doublets of the 9+2 axoneme occurring in most motile cilia.	tmpzr1t_l9r_go_relaxed.owl	axonemal microtubule central pair|axoneme microtubule central pair|central pair|central-pair microtubules|axoneme central pair							pr	2013-12-12T11:07:09Z					cellular_component											owl:Class	
GO:0034739	biolink:NamedThing	histone deacetylase activity (H4-K16 specific)	Catalysis of the reaction: histone H4 N6-acetyl-L-lysine (position 16) + H2O = histone H4 L-lysine (position 16) + acetate. This reaction represents the removal of an acetyl group from lysine at position 16 of the histone H4 protein.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0070933	biolink:NamedThing	histone H4 deacetylation	The modification of histone H4 by the removal of one or more acetyl groups.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-09-16T04:53:06Z					biological_process											owl:Class	
GO:1900205	biolink:NamedThing	apoptotic process involved in metanephric nephron tubule development	Any apoptotic process that is involved in metanephric nephron tubule development.	tmpzr1t_l9r_go_relaxed.owl	programmed cell death by apoptosis of metanephric nephron tubule development|type I programmed cell death of metanephric nephron tubule development|apoptosis of metanephric nephron tubule development|signaling (initiator) caspase activity of metanephric nephron tubule development|apoptotic program of metanephric nephron tubule development|apoptotic process of metanephric nephron tubule development|apoptotic cell death of metanephric nephron tubule development|apoptotic programmed cell death of metanephric nephron tubule development							yaf	2012-03-21T01:21:45Z					biological_process											owl:Class	
GO:0044625	biolink:NamedThing	envenomation resulting in negative regulation of cell migration in other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the negative regulation of cell migration in the bitten organism.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-07-04T05:07:16Z					biological_process											owl:Class	
GO:0044622	biolink:NamedThing	negative regulation of cell migration in other organism	Any process that stops, prevents, or reduces the frequency, rate or extent of cell migration in a second organism.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-07-04T04:42:14Z					biological_process											owl:Class	
GO:0030126	biolink:NamedThing	COPI vesicle coat	One of two multimeric complexes that forms a membrane vesicle coat. The mammalian COPI subunits are called alpha-, beta-, beta'-, gamma-, delta-, epsilon- and zeta-COP. Vesicles with COPI coats are found associated with Golgi membranes at steady state.	tmpzr1t_l9r_go_relaxed.owl	coatomer											GO:0017167		cellular_component											owl:Class	
GO:0017077	biolink:NamedThing	oxidative phosphorylation uncoupler activity	Enables the transfer of protons from mitochondrial intermembrane space into mitochondrial matrix, dissipating the proton gradient across the mitochondrial inner membrane established by the electron transport chain during the oxidative phosphorylation (proton leak). Proton leak uncouples the processes of electron transport/proton generation and ATP synthesis.	tmpzr1t_l9r_go_relaxed.owl	uncoupling protein activity|mitochondrial uncoupling protein activity											GO:0015302		molecular_function											owl:Class	
GO:0044166	biolink:NamedThing	host cell endoplasmic reticulum lumen	The volume enclosed by the membranes of the host cell endoplasmic reticulum.	tmpzr1t_l9r_go_relaxed.owl	host endoplasmic reticulum lumen							jl	2009-09-04T11:13:30Z					cellular_component											owl:Class	
GO:0044165	biolink:NamedThing	host cell endoplasmic reticulum	The irregular network of unit membranes, visible only by electron microscopy, that occurs in the host cell cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The host ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).	tmpzr1t_l9r_go_relaxed.owl	host endoplasmic reticulum							jl	2009-09-04T11:08:09Z					cellular_component											owl:Class	
GO:0015279	biolink:NamedThing	store-operated calcium channel activity	A ligand-gated ion channel activity which transports calcium in response to emptying of intracellular calcium stores.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-434798									molecular_function											owl:Class	
GO:0010704	biolink:NamedThing	meiotic DNA double-strand break processing involved in meiotic gene conversion	The cell cycle process in which the 5' to 3' exonucleolytic resection of the DNA at the site of the break to form a 3' single-strand DNA overhang resulting in the transfer of genetic information from one helix to another.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1905858	biolink:NamedThing	regulation of heparan sulfate proteoglycan binding	Any process that modulates the frequency, rate or extent of heparan sulfate proteoglycan binding.	tmpzr1t_l9r_go_relaxed.owl	regulation of heparin proteoglycan binding							bc	2017-01-23T14:25:10Z					biological_process											owl:Class	
GO:0044799	biolink:NamedThing	NarGHI complex	A heterotrimeric protein complex with iron-sulfur and molybdenum cofactors that functions as a terminal reductase in electron transport pathways that operate during anaerobic nitrate respiration. In E. coli electrons are passed from the FdnGHI complex to the NarGHI complex via menoquinone and menaquinol. Within NarGHI, electrons are passed from the two heme molecules in the NarI subunit down a Fe-S cluster chain in the NarH and NarG subunits to the Molybdenum cofactor, Mo-bisMGD, in the NarG subunit.	tmpzr1t_l9r_go_relaxed.owl	cytoplasmic membrane-bound quinol-nitrate oxidoreductase|nitrate reductase A							jl	2013-08-29T14:17:41Z					cellular_component											owl:Class	
GO:0070470	biolink:NamedThing	plasma membrane respirasome	A respiratory chain located in the plasma membrane of a cell; made up of the protein complexes that form the electron transport system (the respiratory chain), associated with the plasma membrane. The respiratory chain complexes transfer electrons from an electron donor to an electron acceptor and are associated with a proton pump to create a transmembrane electrochemical gradient.	tmpzr1t_l9r_go_relaxed.owl	plasma membrane respiratory chain|plasma membrane electron transport chain	https://github.com/geneontology/go-ontology/issues/12846												cellular_component											owl:Class	
GO:0021555	biolink:NamedThing	midbrain-hindbrain boundary morphogenesis	The process in which the anatomical structure of the midbrain-hindbrain boundary is generated and organized. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate.	tmpzr1t_l9r_go_relaxed.owl	isthmus morphogenesis|MHB morphogenesis													biological_process											owl:Class	
GO:0051208	biolink:NamedThing	sequestering of calcium ion	The process of binding or confining calcium ions such that they are separated from other components of a biological system.	tmpzr1t_l9r_go_relaxed.owl	calcium ion (Ca2+) sequestration|calcium ion (Ca2+) storage|sequestration of calcium ion (Ca2+)|calcium ion storage activity|retention of calcium ion (Ca2+)|calcium ion (Ca2+) sequestering|sequestering of calcium ion (Ca2+)|storage of calcium ion (Ca2+)|calcium ion (Ca2+) retention|negative regulation of calcium ion (Ca2+) transport													biological_process											owl:Class	
GO:0021602	biolink:NamedThing	cranial nerve morphogenesis	The process in which the anatomical structure of the cranial nerves are generated and organized. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0007114	biolink:NamedThing	cell budding	A form of asexual reproduction, occurring in certain bacteria and fungi (e.g. yeasts) and some primitive animals in which an individual arises from a daughter cell formed by pinching off a part of the parent cell. The budlike outgrowths so formed may sometimes remain attached to the parent cell.	tmpzr1t_l9r_go_relaxed.owl	budding													biological_process											owl:Class	
GO:0048705	biolink:NamedThing	skeletal system morphogenesis	The process in which the anatomical structures of the skeleton are generated and organized.	tmpzr1t_l9r_go_relaxed.owl	skeletal morphogenesis													biological_process											owl:Class	
GO:1904835	biolink:NamedThing	dorsal root ganglion morphogenesis	The developmental process by which a dorsal root ganglion is generated and organized.	tmpzr1t_l9r_go_relaxed.owl	ganglion spinale morphogenesis|posterior root ganglion morphogenesis|ganglion spinalis morphogenesis|spinal ganglion part of peripheral nervous system morphogenesis|dorsal root ganglia morphogenesis|spinal ganglion morphogenesis|DRG morphogenesis|ganglion of dorsal root morphogenesis|ganglion sensorium nervi spinalis morphogenesis							bf	2015-12-01T16:41:17Z					biological_process											owl:Class	
GO:1990791	biolink:NamedThing	dorsal root ganglion development	The process whose specific outcome is the progression of a dorsal root ganglion over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl	DRG development							sl	2015-07-02T22:09:54Z					biological_process											owl:Class	
GO:0032209	biolink:NamedThing	positive regulation of telomere maintenance via recombination	Any process that activates or increases the frequency, rate or extent of a recombinational process involved in the maintenance of proper telomeric length.	tmpzr1t_l9r_go_relaxed.owl	up regulation of telomere maintenance via recombination|stimulation of telomere maintenance via recombination|activation of telomere maintenance via recombination|upregulation of telomere maintenance via recombination|up-regulation of telomere maintenance via recombination													biological_process											owl:Class	
GO:0000722	biolink:NamedThing	telomere maintenance via recombination	Any recombinational process that contributes to the maintenance of proper telomeric length.	tmpzr1t_l9r_go_relaxed.owl	telomerase-independent telomere maintenance													biological_process											owl:Class	
GO:0021997	biolink:NamedThing	neural plate axis specification	The pattern specification process in which the axes of the nervous system are established.	tmpzr1t_l9r_go_relaxed.owl	neural plate axis determination													biological_process											owl:Class	
GO:1904256	biolink:NamedThing	positive regulation of iron ion transmembrane transporter activity	Any process that activates or increases the frequency, rate or extent of an iron transmembrane transporter activity.	tmpzr1t_l9r_go_relaxed.owl	activation of iron channel activity|upregulation of iron channel activity|up-regulation of iron cation channel activity|positive regulation of iron-specific channel activity|activation of iron cation channel activity|up regulation of iron cation channel activity|positive regulation of iron channel activity|upregulation of iron cation channel activity|up regulation of iron channel activity|up-regulation of iron-specific channel activity|positive regulation of iron cation channel activity|upregulation of iron-specific channel activity|positive regulation of iron transmembrane transporter activity|activation of iron-specific channel activity|up-regulation of iron channel activity|up regulation of iron-specific channel activity							kom	2015-05-20T14:05:12Z					biological_process											owl:Class	
GO:0005381	biolink:NamedThing	iron ion transmembrane transporter activity	Enables the transfer of iron (Fe) ions from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	multicopper ferroxidase iron transport mediator activity|iron transporter activity|zinc, iron permease activity|iron cation channel activity|iron channel activity|transmembrane iron permease activity|transmembrane iron ion permease activity	https://github.com/geneontology/go-ontology/issues/17162			Reactome:R-HSA-904830|Reactome:R-HSA-917936|Reactome:R-HSA-5623558|Reactome:R-HSA-435349|Reactome:R-HSA-5655733	An example of this is mouse ferroportin (UniProtKB:Q9JHI9), which transports iron out of the cell.						GO:0097689|GO:0005382|GO:0016033		molecular_function											owl:Class	
GO:0007600	biolink:NamedThing	sensory perception	The series of events required for an organism to receive a sensory stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Perception									biological_process											owl:Class	
GO:0010085	biolink:NamedThing	polarity specification of proximal/distal axis	Any process resulting in the establishment of polarity along the proximal/distal axis.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0009946	biolink:NamedThing	proximal/distal axis specification	The establishment, maintenance and elaboration of the proximal/distal axis. The proximal/distal axis is defined by a line that runs from main body (proximal end) of an organism outward (distal end).	tmpzr1t_l9r_go_relaxed.owl	proximodistal axis specification|proximal/distal axis determination													biological_process											owl:Class	
GO:0061774	biolink:NamedThing	cohesin unloading	Negative regulation of sister chromatid cohesion by the topological unlinking of a cohesin ring to DNA.	tmpzr1t_l9r_go_relaxed.owl	DNA exit from the cohesin ring							dph	2016-07-13T12:40:25Z					biological_process											owl:Class	
GO:2000932	biolink:NamedThing	positive regulation of cellobiose metabolic process	Any process that activates or increases the frequency, rate or extent of cellobiose metabolic process.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of cellobiose metabolism							tt	2011-08-01T12:43:01Z					biological_process											owl:Class	
GO:0035003	biolink:NamedThing	subapical complex	The most apical region of the lateral plasma membrane of an invertebrate epithelial cell. The subapical complex lies above the zonula adherens and the septate junction, and is comparable to the position of the tight junction of vertebrate cells.	tmpzr1t_l9r_go_relaxed.owl	SAC													cellular_component											owl:Class	
GO:0060750	biolink:NamedThing	epithelial cell proliferation involved in mammary gland duct elongation	The multiplication or reproduction of mammary gland branch epithelial cells, resulting in the elongation of the branch. The mammary gland branch differs from the bud in that it is not the initial curved portion of the outgrowth.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-06-22T10:58:12Z					biological_process											owl:Class	
GO:0060751	biolink:NamedThing	branch elongation involved in mammary gland duct branching	The developmental growth process in which a branch of a mammary gland duct elongates.	tmpzr1t_l9r_go_relaxed.owl	mammary gland duct branch elongation							dph	2009-06-22T11:02:44Z					biological_process											owl:Class	
GO:0001706	biolink:NamedThing	endoderm formation	The formation of the endoderm during gastrulation.	tmpzr1t_l9r_go_relaxed.owl	endoblast formation													biological_process											owl:Class	
GO:0007492	biolink:NamedThing	endoderm development	The process whose specific outcome is the progression of the endoderm over time, from its formation to the mature structure. The endoderm is the innermost germ layer that develops into the gastrointestinal tract, the lungs and associated tissues.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0051329	biolink:NamedThing	mitotic interphase	The cell cycle phase following cytokinesis which begins with G1 phase, proceeds through S phase and G2 phase and ends when mitotic prophase begins. During interphase the cell readies itself for mitosis and the replication of its DNA occurs.	tmpzr1t_l9r_go_relaxed.owl	interphase of mitotic cell cycle					Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).								biological_process											owl:Class	
GO:0075310	biolink:NamedThing	regulation of sporangium development	Any process that modulates the frequency, rate or extent of sporangium development, a process that leads to the formation of sporangium, a single-celled or many-celled structure in which spores are produced, as in fungi, algae, mosses, and ferns, gymnosperms, angiosperms.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0010208	biolink:NamedThing	pollen wall assembly	The formation of reticulate pollen wall pattern consisting of two layers, exine and intine.	tmpzr1t_l9r_go_relaxed.owl	pollen wall formation													biological_process											owl:Class	
GO:0009555	biolink:NamedThing	pollen development	The process whose specific outcome is the progression of the pollen grain over time, from its formation to the mature structure. The process begins with the meiosis of the microsporocyte to form four haploid microspores. The nucleus of each microspore then divides by mitosis to form a two-celled organism, the pollen grain, that contains a tube cell as well as a smaller generative cell. The pollen grain is surrounded by an elaborate cell wall. In some species, the generative cell immediately divides again to give a pair of sperm cells. In most flowering plants, however this division takes place later, in the tube that develops when a pollen grain germinates.	tmpzr1t_l9r_go_relaxed.owl	microgametophyte development|male gametophyte development|male gametophyte formation|formation of generative and vegetative cells|pollen grain formation											GO:0009564|GO:0048231		biological_process											owl:Class	
GO:0071472	biolink:NamedThing	cellular response to salt stress	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.	tmpzr1t_l9r_go_relaxed.owl	cellular response to ionic osmotic stress|cellular salinity response							mah	2009-12-18T11:48:23Z					biological_process											owl:Class	
GO:0045061	biolink:NamedThing	thymic T cell selection	The process of T cell selection that occurs in the thymus.	tmpzr1t_l9r_go_relaxed.owl	thymic T lymphocyte selection|thymic T-lymphocyte selection|thymic T-cell selection													biological_process											owl:Class	
GO:1900660	biolink:NamedThing	positive regulation of emericellamide biosynthetic process	Any process that activates or increases the frequency, rate or extent of emericellamide biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of emericellamide formation|activation of emericellamide biosynthesis|upregulation of emericellamide synthesis|up-regulation of emericellamide anabolism|up regulation of emericellamide biosynthetic process|activation of emericellamide formation|activation of emericellamide biosynthetic process|up-regulation of emericellamide biosynthesis|up regulation of emericellamide formation|upregulation of emericellamide biosynthetic process|positive regulation of emericellamide biosynthesis|up-regulation of emericellamide formation|activation of emericellamide synthesis|up-regulation of emericellamide synthesis|upregulation of emericellamide formation|upregulation of emericellamide anabolism|positive regulation of emericellamide synthesis|up regulation of emericellamide biosynthesis|up regulation of emericellamide anabolism|up-regulation of emericellamide biosynthetic process|upregulation of emericellamide biosynthesis|up regulation of emericellamide synthesis|activation of emericellamide anabolism|positive regulation of emericellamide anabolism							di	2012-05-22T04:10:51Z					biological_process											owl:Class	
GO:1904930	biolink:NamedThing	amphisome membrane	Any membrane that is part of an amphisome.	tmpzr1t_l9r_go_relaxed.owl								pr	2016-01-29T11:40:13Z					cellular_component											owl:Class	
GO:0075286	biolink:NamedThing	regulation of sporangiospore formation	Any process that modulates the frequency, rate or extent of sporangiospore formation, a process in which sporangiospores, a type of asexual spore found in fungi, are formed. Sporangiospores are formed within sac-like structure, the sporangium, following the division of the cytoplasm.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0061357	biolink:NamedThing	positive regulation of Wnt protein secretion	Any process that activates or increases the frequency, rate or extent of the controlled release of a Wnt protein from a cell.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-10-08T01:12:21Z					biological_process											owl:Class	
GO:0005460	biolink:NamedThing	UDP-glucose transmembrane transporter activity	Enables the transfer of a UDP-glucose from one side of a membrane to the other. UDP-glucose is a substance composed of glucose in glycosidic linkage with uridine diphosphate.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0015786	biolink:NamedThing	UDP-glucose transmembrane transport	The process in which UDP-glucose is transported across a membrane.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1900208	biolink:NamedThing	regulation of cardiolipin metabolic process	Any process that modulates the frequency, rate or extent of cardiolipin metabolic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of diphosphatidylglycerol metabolic process|regulation of diphosphatidylglycerol metabolism|regulation of cardiolipin metabolism							jl	2012-03-22T10:43:33Z					biological_process											owl:Class	
GO:0035183	biolink:NamedThing	female germline ring canal inner rim	A proteinaceous actin-rich layer of the insect ovarian ring canal that forms subcortically to the outer rim. The electron dense inner rim accumulates after the final mitotic division of each germline syncytia, and contains actin, a phosphotyrosine protein, and a number of cytoskeletal proteins.	tmpzr1t_l9r_go_relaxed.owl	ovarian ring canal inner rim|germline ring canal inner rim|nurse cell ring canal inner rim					See also the fly_anatomy.ontology term 'inner nurse cell ring canal rim ; FBbt:00004881'.								cellular_component											owl:Class	
GO:0035324	biolink:NamedThing	female germline ring canal	An intercellular bridge that connects the germline cells of a female cyst.	tmpzr1t_l9r_go_relaxed.owl	nurse cell ring canal|ovarian ring canal							bf	2010-02-25T11:06:41Z					cellular_component											owl:Class	
GO:0035368	biolink:NamedThing	selenocysteine insertion sequence binding	Binding to a selenocysteine insertion sequence (SECIS), a regulatory sequence within mRNA which directs incorporation of a selenocysteine at a stop codon (UGA) during translation.	tmpzr1t_l9r_go_relaxed.owl	SECIS binding							bf	2010-03-11T10:42:28Z					molecular_function											owl:Class	
GO:2000294	biolink:NamedThing	positive regulation of defecation	Any process that activates or increases the frequency, rate or extent of defecation.	tmpzr1t_l9r_go_relaxed.owl								bf	2010-12-21T09:23:16Z					biological_process											owl:Class	
GO:0030421	biolink:NamedThing	defecation	The expulsion of feces from the rectum.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Defecation									biological_process											owl:Class	
GO:0030890	biolink:NamedThing	positive regulation of B cell proliferation	Any process that activates or increases the rate or extent of B cell proliferation.	tmpzr1t_l9r_go_relaxed.owl	upregulation of B cell proliferation|stimulation of B cell proliferation|up regulation of B cell proliferation|positive regulation of B lymphocyte proliferation|positive regulation of B-cell proliferation|up-regulation of B cell proliferation|activation of B cell proliferation|positive regulation of B-lymphocyte proliferation													biological_process											owl:Class	
GO:1905881	biolink:NamedThing	positive regulation of oogenesis	Any process that activates or increases the frequency, rate or extent of oogenesis.	tmpzr1t_l9r_go_relaxed.owl	upregulation of ovum development|activation of ovum development|activation of oogenesis|up regulation of oogenesis|up-regulation of ovum development|positive regulation of ovum development|up-regulation of oogenesis|upregulation of oogenesis|up regulation of ovum development							hbye	2017-01-31T09:31:23Z					biological_process											owl:Class	
GO:1904651	biolink:NamedThing	positive regulation of fat cell apoptotic process	Any process that activates or increases the frequency, rate or extent of fat cell apoptotic process.	tmpzr1t_l9r_go_relaxed.owl	upregulation of adipocyte apoptotic process|upregulation of adipose cell apoptotic process|activation of adipose cell apoptosis|up-regulation of fat cell apoptotic process|positive regulation of fat cell apoptosis|up regulation of adipose cell apoptotic process|up-regulation of adipocyte apoptotic process|activation of adipose cell apoptotic process|up-regulation of adipocyte apoptosis|up-regulation of fat cell apoptosis|activation of fat cell apoptotic process|up-regulation of adipose cell apoptotic process|positive regulation of adipocyte apoptotic process|activation of fat cell apoptosis|upregulation of fat cell apoptotic process|up regulation of adipose cell apoptosis|up regulation of fat cell apoptosis|positive regulation of adipose cell apoptosis|positive regulation of adipose cell apoptotic process|upregulation of adipose cell apoptosis|upregulation of adipocyte apoptosis|positive regulation of adipocyte apoptosis|up-regulation of adipose cell apoptosis|up regulation of adipocyte apoptosis|activation of adipocyte apoptosis|activation of adipocyte apoptotic process|upregulation of fat cell apoptosis|up regulation of adipocyte apoptotic process|up regulation of fat cell apoptotic process							sl	2015-08-31T20:59:40Z					biological_process											owl:Class	
GO:0071971	biolink:NamedThing	extracellular exosome assembly	The aggregation, arrangement and bonding together of a set of components to form an extracellular vesicular exosome, a membrane-bounded vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Exosomes are defined by their size, which generally ranges from 30 nm to 100 nm.	tmpzr1t_l9r_go_relaxed.owl	extracellular vesicular exosome assembly							mah	2010-10-18T03:44:18Z					biological_process											owl:Class	
GO:0003303	biolink:NamedThing	BMP signaling pathway involved in heart jogging	A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, which contributes to the process of heart jogging.	tmpzr1t_l9r_go_relaxed.owl	BMP signalling pathway involved in heart jogging							dph	2009-10-22T11:00:58Z					biological_process											owl:Class	
GO:0003146	biolink:NamedThing	heart jogging	The morphogenetic process in which the heart cone is displaced to the left with respect to the vector of the anterior-posterior axis.	tmpzr1t_l9r_go_relaxed.owl	cardiac jogging							tb	2009-09-22T06:11:41Z					biological_process											owl:Class	
GO:0030999	biolink:NamedThing	linear element assembly	The cell cycle process in which linear elements are assembled in association with fission yeast chromosomes during meiotic prophase. Linear element assembly begins with LinE complex formation and ends when LinE complexes are associated with chromatin in structures visible as nuclear foci. A linear element is a proteinaceous scaffold related to the synaptonemal complex.	tmpzr1t_l9r_go_relaxed.owl	linear element formation													biological_process											owl:Class	
GO:1905084	biolink:NamedThing	positive regulation of mitochondrial translational elongation	Any process that activates or increases the frequency, rate or extent of mitochondrial translational elongation.	tmpzr1t_l9r_go_relaxed.owl	activation of mitochondrial translation elongation|up regulation of mitochondrial translation elongation|up regulation of mitochondrial translational elongation|activation of mitochondrial translational elongation|up-regulation of mitochondrial translational elongation|upregulation of mitochondrial translational elongation|upregulation of mitochondrial translation elongation|up-regulation of mitochondrial translation elongation|positive regulation of mitochondrial translation elongation							hjd	2016-03-25T17:37:22Z					biological_process											owl:Class	
GO:0070125	biolink:NamedThing	mitochondrial translational elongation	The successive addition of amino acid residues to a nascent polypeptide chain during protein biosynthesis in a mitochondrion.	tmpzr1t_l9r_go_relaxed.owl	mitochondrial translation elongation													biological_process											owl:Class	
GO:1905880	biolink:NamedThing	negative regulation of oogenesis	Any process that stops, prevents or reduces the frequency, rate or extent of oogenesis.	tmpzr1t_l9r_go_relaxed.owl	downregulation of ovum development|negative regulation of ovum development|inhibition of ovum development|downregulation of oogenesis|down-regulation of oogenesis|down-regulation of ovum development|down regulation of oogenesis|inhibition of oogenesis|down regulation of ovum development							hbye	2017-01-31T09:31:15Z					biological_process											owl:Class	
GO:0002331	biolink:NamedThing	pre-B cell allelic exclusion	Expression of a single heavy chain allele during pre-B cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	pre-B lymphocyte allelic exclusion													biological_process											owl:Class	
GO:0002329	biolink:NamedThing	pre-B cell differentiation	The process in which a precursor cell type acquires the specialized features of a pre-B cell. Pre-B cells follow the pro-B cell stage of immature B cell differentiation and undergo rearrangement of heavy chain V, D, and J gene segments.	tmpzr1t_l9r_go_relaxed.owl	pre-B lymphocyte differentiation|pre-B cell development					Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.								biological_process											owl:Class	
GO:0010776	biolink:NamedThing	meiotic mismatch repair involved in meiotic gene conversion	A system for the identification and correction of base-base mismatches, small insertion-deletion loops, and regions of heterology that are present in duplex DNA formed with strands from two recombining molecules resulting in meiotic gene conversion. Meiotic gene conversion is the cell cycle process in which genetic information is transferred from one helix to another.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0042338	biolink:NamedThing	cuticle development involved in collagen and cuticulin-based cuticle molting cycle	Synthesis and deposition of a collagen and cuticulin-based noncellular, hardened, or membranous secretion from an epithelial sheet, occurring as part of the molting cycle. An example of this process is found in Caenorhabditis elegans.	tmpzr1t_l9r_go_relaxed.owl	cuticle synthesis during molting|collagen and cuticulin-based cuticle development during molting|cuticle formation during molting|cuticle biosynthetic process during molting|cuticle anabolism during molting													biological_process											owl:Class	
GO:0018996	biolink:NamedThing	molting cycle, collagen and cuticulin-based cuticle	The periodic shedding of part or all of a collagen and cuticulin-based cuticle, which is then replaced by a new collagen and cuticulin-based cuticle. An example of this is found in the Nematode worm, Caenorhabditis elegans.	tmpzr1t_l9r_go_relaxed.owl	collagen and cuticulin-based cuticle molting cycle													biological_process											owl:Class	
GO:0033362	biolink:NamedThing	lysine biosynthetic process via diaminopimelate, diaminopimelate-aminotransferase pathway	The chemical reactions and pathways resulting in the formation of lysine, via the intermediate diaminopimelate; in this pathway tetrahydrodipicolinate is converted to meso-diaminopimelate in two enzymatic steps.	tmpzr1t_l9r_go_relaxed.owl	lysine anabolism via diaminopimelate, diaminopimelate-aminotransferase pathway|lysine synthesis via diaminopimelate, diaminopimelate-aminotransferase pathway|lysine formation via diaminopimelate, diaminopimelate-aminotransferase pathway|lysine biosynthesis via diaminopimelate, diaminopimelate-aminotransferase pathway				MetaCyc:PWY-5097									biological_process											owl:Class	
GO:0044292	biolink:NamedThing	dendrite terminus	A structure at the distal end of a dendrite adapted to carry out a specific function, e.g. dendriole.	tmpzr1t_l9r_go_relaxed.owl	dendrite terminal specialization|terminal specialization of a dendrite|dendrite terminal|terminal specialization				NIF_Subcellular:sao28175134			jl	2010-02-04T03:14:37Z					cellular_component											owl:Class	
GO:2000095	biolink:NamedThing	regulation of Wnt signaling pathway, planar cell polarity pathway	Any process that modulates the frequency, rate or extent of Wnt signaling pathway, planar cell polarity pathway.	tmpzr1t_l9r_go_relaxed.owl	regulation of PCP pathway|regulation of Wnt-JNK signaling pathway|regulation of Wnt receptor signalling pathway, planar cell polarity pathway|regulation of Wnt-activated signaling pathway, planar cell polarity pathway|regulation of non-canonical Wnt signaling pathway|regulation of Wnt-PCP signaling pathway|regulation of Wnt receptor signaling pathway, planar cell polarity pathway							jl	2010-09-08T01:07:39Z					biological_process											owl:Class	
GO:0044169	biolink:NamedThing	host cell rough endoplasmic reticulum membrane	The lipid bilayer surrounding the host cell rough endoplasmic reticulum.	tmpzr1t_l9r_go_relaxed.owl	host rough endoplasmic reticulum membrane							jl	2009-09-04T11:30:38Z					cellular_component											owl:Class	
GO:0044168	biolink:NamedThing	host cell rough endoplasmic reticulum	The irregular network of unit membranes, visible only by electron microscopy, that occurs in the host cell cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The host rough ER has ribosomes adhering to the outer surface.	tmpzr1t_l9r_go_relaxed.owl	host rough endoplasmic reticulum							jl	2009-09-04T11:23:28Z					cellular_component											owl:Class	
GO:0032809	biolink:NamedThing	neuronal cell body membrane	The plasma membrane of a neuron cell body - excludes the plasma membrane of cell projections such as axons and dendrites.	tmpzr1t_l9r_go_relaxed.owl	neuron cell body membrane|neuronal cell soma membrane													cellular_component											owl:Class	
GO:0043025	biolink:NamedThing	neuronal cell body	The portion of a neuron that includes the nucleus, but excludes cell projections such as axons and dendrites.	tmpzr1t_l9r_go_relaxed.owl	neuronal cell soma|neuron cell body				Wikipedia:Soma_(biology)|NIF_Subcellular:sao1044911821	Note that 'cell body' and 'cell soma' are not used in the literature for cells that lack projections, nor for some cells (e.g. yeast with mating projections) that do have projections.								cellular_component											owl:Class	
GO:0002470	biolink:NamedThing	plasmacytoid dendritic cell antigen processing and presentation	The process in which a plasmacytoid dendritic cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0035723	biolink:NamedThing	interleukin-15-mediated signaling pathway	A series of molecular signals initiated by the binding of interleukin-15 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.	tmpzr1t_l9r_go_relaxed.owl	interleukin-15-mediated signalling pathway|IL-15-mediated signaling pathway							bf	2011-03-07T11:28:29Z					biological_process											owl:Class	
GO:0071350	biolink:NamedThing	cellular response to interleukin-15	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-15 stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to IL-15							mah	2009-12-11T02:49:51Z					biological_process											owl:Class	
GO:0035021	biolink:NamedThing	negative regulation of Rac protein signal transduction	Any process that stops, prevents, or reduces the frequency, rate or extent of Rac protein signal transduction.	tmpzr1t_l9r_go_relaxed.owl	inhibition of Rac protein signal transduction|downregulation of Rac protein signal transduction|down regulation of Rac protein signal transduction|down-regulation of Rac protein signal transduction													biological_process											owl:Class	
GO:0016601	biolink:NamedThing	Rac protein signal transduction	A series of molecular signals within the cell that are mediated by a member of the Rac family of proteins switching to a GTP-bound active state.	tmpzr1t_l9r_go_relaxed.owl	Rac mediated signal transduction													biological_process											owl:Class	
GO:0016036	biolink:NamedThing	cellular response to phosphate starvation	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of phosphate.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1904582	biolink:NamedThing	positive regulation of intracellular mRNA localization	Any process that activates or increases the frequency, rate or extent of intracellular mRNA localization.	tmpzr1t_l9r_go_relaxed.owl	up regulation of intracellular mRNA positioning|up regulation of intracellular mRNA localization|positive regulation of intracellular mRNA localisation|upregulation of intracellular mRNA localization|activation of intracellular mRNA localization|activation of establishment and maintenance of intracellular RNA localization|activation of intracellular mRNA positioning|activation of mRNA localization, intracellular|up-regulation of mRNA localization, intracellular|upregulation of intracellular mRNA localisation|positive regulation of establishment and maintenance of intracellular RNA localization|positive regulation of mRNA localization, intracellular|up-regulation of mRNA positioning, intracellular|activation of mRNA positioning, intracellular|upregulation of mRNA positioning, intracellular|up regulation of intracellular mRNA localisation|up regulation of establishment and maintenance of intracellular RNA localization|upregulation of mRNA localization, intracellular|positive regulation of mRNA positioning, intracellular|upregulation of intracellular mRNA positioning|upregulation of establishment and maintenance of intracellular RNA localization|up regulation of mRNA localization, intracellular|up-regulation of intracellular mRNA positioning|activation of intracellular mRNA localisation|up regulation of mRNA positioning, intracellular|positive regulation of intracellular mRNA positioning|up-regulation of establishment and maintenance of intracellular RNA localization|up-regulation of intracellular mRNA localisation|up-regulation of intracellular mRNA localization							sl	2015-08-19T23:40:38Z					biological_process											owl:Class	
GO:0008298	biolink:NamedThing	intracellular mRNA localization	Any process in which mRNA is transported to, or maintained in, a specific location within the cell.	tmpzr1t_l9r_go_relaxed.owl	intracellular mRNA positioning|establishment and maintenance of intracellular RNA localization|mRNA positioning, intracellular|mRNA localization, intracellular|intracellular mRNA localisation													biological_process											owl:Class	
GO:0071998	biolink:NamedThing	ascospore release from ascus	A developmental process that results in the discharge of ascospores from the ascus. Ascospore release may be active or passive.	tmpzr1t_l9r_go_relaxed.owl	ascospore liberation							mah	2010-10-25T03:41:44Z					biological_process											owl:Class	
GO:1901969	biolink:NamedThing	positive regulation of polynucleotide 3'-phosphatase activity	Any process that activates or increases the frequency, rate or extent of polynucleotide 3'-phosphatase activity.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of deoxyribonucleate 3'-phosphatase activity|upregulation of 5'-polynucleotidekinase 3'-phosphatase activity|activation of DNA 3'-phosphatase activity|up-regulation of polynucleotide 3'-phosphatase activity|up regulation of deoxyribonucleate 3'-phosphatase activity|upregulation of 2'(3')-polynucleotidase activity|up-regulation of DNA 3'-phosphatase activity|positive regulation of 5'-polynucleotidekinase 3'-phosphatase activity|activation of deoxyribonucleate 3'-phosphatase activity|upregulation of polynucleotide 3'-phosphatase activity|up regulation of 2'(3')-polynucleotidase activity|activation of 5'-polynucleotidekinase 3'-phosphatase activity|up regulation of 5'-polynucleotidekinase 3'-phosphatase activity|up-regulation of deoxyribonucleate 3'-phosphatase activity|activation of polynucleotide 3'-phosphohydrolase activity|up-regulation of 5'-polynucleotidekinase 3'-phosphatase activity|upregulation of polynucleotide 3'-phosphohydrolase activity|activation of 2'(3')-polynucleotidase activity|up regulation of polynucleotide 3'-phosphohydrolase activity|up-regulation of polynucleotide 3'-phosphohydrolase activity|positive regulation of polynucleotide 3'-phosphohydrolase activity|positive regulation of 2'(3')-polynucleotidase activity|upregulation of deoxyribonucleate 3'-phosphatase activity|upregulation of DNA 3'-phosphatase activity|up regulation of polynucleotide 3'-phosphatase activity|up regulation of DNA 3'-phosphatase activity|activation of polynucleotide 3'-phosphatase activity|positive regulation of DNA 3'-phosphatase activity|up-regulation of 2'(3')-polynucleotidase activity							tb	2013-02-22T00:58:31Z					biological_process											owl:Class	
GO:0046403	biolink:NamedThing	polynucleotide 3'-phosphatase activity	Catalysis of the reaction: 3'-phosphopolynucleotide + H2O = a polynucleotide + phosphate. Hydrolyzes the free 3'-phosphate resulting from single strand breaks in DNA due to oxidative damage.	tmpzr1t_l9r_go_relaxed.owl	DNA 3'-phosphatase activity|polynucleotide 3'-phosphohydrolase activity|deoxyribonucleate 3'-phosphatase activity|5'-polynucleotidekinase 3'-phosphatase activity|2'(3')-polynucleotidase activity				EC:3.1.3.32|RHEA:14113|MetaCyc:POLYNUCLEOTIDE-3-PHOSPHATASE-RXN|Reactome:R-HSA-5649705									molecular_function											owl:Class	
GO:1902775	biolink:NamedThing	mitochondrial large ribosomal subunit assembly	The aggregation, arrangement and bonding together of a set of components to form a mitochondrial large ribosomal subunit.	tmpzr1t_l9r_go_relaxed.owl	39S ribosomal subunit, mitochondrial formation|mitochondrial large ribosomal subunit formation|39S ribosomal subunit, mitochondrial assembly							mcc	2014-03-18T14:32:19Z					biological_process											owl:Class	
GO:0061668	biolink:NamedThing	mitochondrial ribosome assembly	The aggregation, arrangement and bonding together of the mitochondrial ribosome and of its subunits.	tmpzr1t_l9r_go_relaxed.owl								dph	2014-11-07T15:32:20Z					biological_process											owl:Class	
GO:0048843	biolink:NamedThing	negative regulation of axon extension involved in axon guidance	Any process that stops, prevents, or reduces the frequency, rate or extent of axon extension involved in axon guidance.	tmpzr1t_l9r_go_relaxed.owl	inhibition of axon extension involved in axon guidance|downregulation of axon extension involved in axon guidance|down regulation of axon extension involved in axon guidance|down-regulation of axon extension involved in axon guidance													biological_process											owl:Class	
GO:0048846	biolink:NamedThing	axon extension involved in axon guidance	The long distance growth of a single cell process, that is involved in the migration of an axon growth cone, where the migration is directed to a specific target site by a combination of attractive and repulsive cues.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0045668	biolink:NamedThing	negative regulation of osteoblast differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of osteoblast differentiation.	tmpzr1t_l9r_go_relaxed.owl	downregulation of osteoblast differentiation|down-regulation of osteoblast differentiation|inhibition of osteoblast differentiation|down regulation of osteoblast differentiation													biological_process											owl:Class	
GO:0001649	biolink:NamedThing	osteoblast differentiation	The process whereby a relatively unspecialized cell acquires the specialized features of an osteoblast, a mesodermal or neural crest cell that gives rise to bone.	tmpzr1t_l9r_go_relaxed.owl	osteoblast cell differentiation													biological_process											owl:Class	
GO:0060484	biolink:NamedThing	lung-associated mesenchyme development	The biological process whose specific outcome is the progression of a lung-associated mesenchyme from an initial condition to its mature state. This process begins with the formation of lung-associated mesenchyme and ends with the mature structure. Lung-associated mesenchyme is the tissue made up of loosely connected mesenchymal cells in the lung.	tmpzr1t_l9r_go_relaxed.owl	lung mesenchyme development|pulmonary mesenchyme development													biological_process											owl:Class	
GO:0061228	biolink:NamedThing	mesonephric nephron morphogenesis	The process in which the anatomical structures of the mesonephric nephron are generated and organized. A mesonephric nephron is the functional unit of the mesonephros.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-08-19T02:26:24Z					biological_process											owl:Class	
GO:0070202	biolink:NamedThing	regulation of establishment of protein localization to chromosome	Any process that modulates the frequency, rate or extent of the directed movement of a protein to a specific location on a chromosome.	tmpzr1t_l9r_go_relaxed.owl	regulation of establishment of protein localisation to chromosome													biological_process											owl:Class	
GO:0070199	biolink:NamedThing	establishment of protein localization to chromosome	The directed movement of a protein to a specific location on a chromosome.	tmpzr1t_l9r_go_relaxed.owl	establishment of protein localisation to chromosome													biological_process											owl:Class	
GO:0046572	biolink:NamedThing	versicolorin B synthase activity	Catalysis of the reaction: versiconal = versicolorin B + H2O.	tmpzr1t_l9r_go_relaxed.owl					RHEA:33859|EC:4.2.1.143|MetaCyc:RXN-9494									molecular_function											owl:Class	
GO:1904888	biolink:NamedThing	cranial skeletal system development	The process whose specific outcome is the progression of a cranial skeletal system over time, from its formation to the mature structure. The cranial skeletal system is the skeletal subdivision of the head, and includes the skull (cranium plus mandible), pharyngeal and/or hyoid apparatus.	tmpzr1t_l9r_go_relaxed.owl	cranium development|craniofacial development|cranial skeleton development|osteocranium development							bf	2016-01-07T13:45:06Z					biological_process											owl:Class	
GO:2000997	biolink:NamedThing	regulation of cellulose catabolic process	Any process that modulates the frequency, rate or extent of cellulose catabolic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of cellulose breakdown|regulation of cellulose degradation|regulation of cellulose catabolism							tt	2011-08-08T03:21:20Z					biological_process											owl:Class	
GO:0030245	biolink:NamedThing	cellulose catabolic process	The chemical reactions and pathways resulting in the breakdown of cellulose, a linear beta1-4 glucan of molecular mass 50-400 kDa with the pyranose units in the -4C1 conformation.	tmpzr1t_l9r_go_relaxed.owl	cellulose degradation|cellulose catabolism|cellulose breakdown											GO:0016179		biological_process											owl:Class	
GO:1905213	biolink:NamedThing	negative regulation of mitotic chromosome condensation	Any process that stops, prevents or reduces the frequency, rate or extent of mitotic chromosome condensation.	tmpzr1t_l9r_go_relaxed.owl								vw	2016-06-03T08:41:08Z					biological_process											owl:Class	
GO:0007076	biolink:NamedThing	mitotic chromosome condensation	The cell cycle process in which chromatin structure is compacted prior to and during mitosis in eukaryotic cells.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0070468	biolink:NamedThing	dentin extracellular matrix secretion	The regulated release by odontoblasts of the extracellular matrix constituents, including collagen, that form the basis of dentin.	tmpzr1t_l9r_go_relaxed.owl	dentine secretion|predentin secretion|dentin secretion													biological_process											owl:Class	
GO:0042475	biolink:NamedThing	odontogenesis of dentin-containing tooth	The process whose specific outcome is the progression of a dentin-containing tooth over time, from its formation to the mature structure. A dentin-containing tooth is a hard, bony organ borne on the jaw or other bone of a vertebrate, and is composed mainly of dentin, a dense calcified substance, covered by a layer of enamel.	tmpzr1t_l9r_go_relaxed.owl	odontosis|odontogenesis of dentine-containing tooth|odontogenesis of dentine-containing teeth|tooth development|odontogeny					Note that placoid scales found in the cartilaginous fishes presumably develop through the same processes, but are found on the dermis, rather than in the mouth or pharynx. See Wikipedia:Placoid_scale#Placoid_scales.								biological_process											owl:Class	
GO:1900057	biolink:NamedThing	positive regulation of leaf senescence	Any process that activates or increases the frequency, rate or extent of leaf senescence.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of leaf senescence|activation of leaf senescence|up regulation of leaf senescence|upregulation of leaf senescence							tb	2012-01-24T11:51:36Z					biological_process											owl:Class	
GO:0010150	biolink:NamedThing	leaf senescence	The process that occurs in a leaf near the end of its active life that is associated with the dismantling of cell components and membranes, loss of functional chloroplasts, and an overall decline in metabolism.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1900039	biolink:NamedThing	positive regulation of cellular response to hypoxia	Any process that activates or increases the frequency, rate or extent of cellular response to hypoxia.	tmpzr1t_l9r_go_relaxed.owl	activation of cellular response to lowered oxygen tension|up-regulation of cellular response to lowered oxygen tension|upregulation of cellular response to hypoxia|activation of cellular response to hypoxic stress|up-regulation of cellular response to hypoxic stress|positive regulation of cellular response to lowered oxygen tension|up regulation of cellular response to hypoxia|upregulation of cellular response to hypoxic stress|activation of cellular response to hypoxia|up regulation of cellular response to hypoxic stress|upregulation of cellular response to lowered oxygen tension|up regulation of cellular response to lowered oxygen tension|positive regulation of cellular response to hypoxic stress|up-regulation of cellular response to hypoxia							yaf	2012-01-17T09:29:19Z					biological_process											owl:Class	
GO:0032710	biolink:NamedThing	negative regulation of interleukin-26 production	Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-26 production.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of IL-26 production|negative regulation of interleukin-26 biosynthetic process|downregulation of interleukin-26 production|down regulation of interleukin-26 production|down-regulation of interleukin-26 production|inhibition of interleukin-26 production											GO:0045534		biological_process											owl:Class	
GO:0051555	biolink:NamedThing	flavonol biosynthetic process	The chemical reactions and pathways resulting in the formation of flavonols, a member of a class of vascular pigments formed by consecutive oxidative processes from the flavonoid intermediates flavanones and dihydroflavonols. Flavonols are the most widespread of the flavonoids and have a wide array of physiological activities.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:PWY-3101									biological_process											owl:Class	
GO:1901029	biolink:NamedThing	negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway	Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of mitochondrial outer membrane permeabilization|down regulation of MOMP|down regulation of mitochondrial outer membrane permeabilization|negative regulation of mitochondrial outer membrane permeabilization|down-regulation of MOMP|inhibition of mitochondrial outer membrane permeabilization|downregulation of MOMP|downregulation of mitochondrial outer membrane permeabilization|negative regulation of MOMP|inhibition of MOMP							pr	2012-06-20T09:19:39Z					biological_process											owl:Class	
GO:0097345	biolink:NamedThing	mitochondrial outer membrane permeabilization	The process by which the mitochondrial outer membrane becomes permeable to the passing of proteins and other molecules from the intermembrane space to the cytosol as part of the apoptotic signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	MOMP|mitochondrion outer membrane permeabilization|mitochondrial outer membrane permeabilization during apoptotic cell death					BAX and BAK are involved in this process, as reviewed in PMID:21760595 (the human proteins have UniProt symbols Q07812 and Q16611 respectively).		pr	2012-06-19T04:06:54Z					biological_process											owl:Class	
GO:1904210	biolink:NamedThing	VCP-NPL4-UFD1 AAA ATPase complex assembly	The aggregation, arrangement and bonding together of a set of components to form a VCP-NPL4-UFD1 AAA ATPase complex.	tmpzr1t_l9r_go_relaxed.owl	p97-Ufd1-Npl4 complex assembly|Cdc48p-Npl4p-Ufd1p AAA ATPase complex assembly|VCP-NPL4-UFD1 AAA ATPase complex formation|Cdc48p-Npl4p-Ufd1p AAA ATPase complex formation|p97-Ufd1-Npl4 complex formation							bf	2015-05-14T10:34:36Z					biological_process											owl:Class	
GO:0090087	biolink:NamedThing	regulation of peptide transport	Any process that modulates the frequency, rate or extent of the directed movement of peptides, compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-10-23T11:21:38Z					biological_process											owl:Class	
GO:0015833	biolink:NamedThing	peptide transport	The directed movement of peptides, compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0010729	biolink:NamedThing	positive regulation of hydrogen peroxide biosynthetic process	Any process that increases the rate, frequency or extent of hydrogen peroxide biosynthesis. The chemical reactions and pathways resulting in the formation of hydrogen peroxide (H2O2), a potentially harmful byproduct of aerobic cellular respiration which can cause damage to DNA.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of hydrogen peroxide biosynthesis													biological_process											owl:Class	
GO:0050665	biolink:NamedThing	hydrogen peroxide biosynthetic process	The chemical reactions and pathways resulting in the formation of hydrogen peroxide (H2O2), a potentially harmful byproduct of aerobic cellular respiration which can cause damage to DNA.	tmpzr1t_l9r_go_relaxed.owl	hydrogen peroxide anabolism|H2O2 biosynthetic process|hydrogen peroxide synthesis|hydrogen peroxide biosynthesis|hydrogen peroxide generation|hydrogen peroxide formation													biological_process											owl:Class	
GO:0060790	biolink:NamedThing	tooth placode formation	The developmental process in which the tooth placode forms. A tooth placode is a thickening of the ectoderm that will give rise to the tooth bud.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-08-04T12:21:47Z					biological_process											owl:Class	
GO:0006836	biolink:NamedThing	neurotransmitter transport	The directed movement of a neurotransmitter into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Neurotransmitters are any chemical substance that is capable of transmitting (or inhibiting the transmission of) a nerve impulse from a neuron to another cell.	tmpzr1t_l9r_go_relaxed.owl	sodium:neurotransmitter transport													biological_process											owl:Class	
GO:0060831	biolink:NamedThing	smoothened signaling pathway involved in dorsal/ventral neural tube patterning	The series of molecular signals generated as a consequence of activation of the transmembrane protein Smoothened contributing to the dorsal/ventral pattern of the neural tube.	tmpzr1t_l9r_go_relaxed.owl	hh signaling pathway involved in dorsal/ventral neural tube patterning|smoothened signalling pathway involved in dorsal/ventral neural tube patterning|hedgehog signaling pathway involved in dorsal/ventral neural tube patterning							dph	2009-08-11T02:12:58Z					biological_process											owl:Class	
GO:0021904	biolink:NamedThing	dorsal/ventral neural tube patterning	The process in which the neural tube is regionalized in the dorsoventral axis.	tmpzr1t_l9r_go_relaxed.owl	dorsoventral neural tube patterning|dorsal-ventral neural tube patterning													biological_process											owl:Class	
GO:0006766	biolink:NamedThing	vitamin metabolic process	The chemical reactions and pathways involving vitamins. Vitamin is a general term for a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body. Vitamins may be water-soluble or fat-soluble and usually serve as components of coenzyme systems.	tmpzr1t_l9r_go_relaxed.owl	vitamin metabolism													biological_process											owl:Class	
GO:0120177	biolink:NamedThing	negative regulation of torso signaling pathway	Any process that stops, prevents, or reduces the frequency, rate or extent of the torso signaling pathway.	tmpzr1t_l9r_go_relaxed.owl								krc	2018-06-07T16:58:08Z					biological_process											owl:Class	
GO:0008293	biolink:NamedThing	torso signaling pathway	A series of molecular signals initiated by the binding of an extracellular ligand to torso (a receptor tyrosine kinase) on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.	tmpzr1t_l9r_go_relaxed.owl	torso signalling pathway													biological_process											owl:Class	
GO:0005577	biolink:NamedThing	fibrinogen complex	A highly soluble, elongated protein complex found in blood plasma and involved in clot formation. It is converted into fibrin monomer by the action of thrombin. In the mouse, fibrinogen is a hexamer, 46 nm long and 9 nm maximal diameter, containing two sets of nonidentical chains (alpha, beta, and gamma) linked together by disulfide bonds.	tmpzr1t_l9r_go_relaxed.owl	fibrinogen|fibrinogen alpha chain|fibrinogen beta chain|fibrinogen gamma chain													cellular_component											owl:Class	
GO:0005615	biolink:NamedThing	extracellular space	That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.	tmpzr1t_l9r_go_relaxed.owl	intercellular space				NIF_Subcellular:sao1425028079	Note that for multicellular organisms, the extracellular space refers to everything outside a cell, but still within the organism (excluding the extracellular matrix). Gene products from a multi-cellular organism that are secreted from a cell into the interstitial fluid or blood can therefore be annotated to this term.								cellular_component											owl:Class	
GO:0034372	biolink:NamedThing	very-low-density lipoprotein particle remodeling	The acquisition, loss or modification of a protein or lipid within a very-low-density lipoprotein particle, including the hydrolysis of triglyceride by hepatic lipase or lipoprotein lipase and the subsequent loss of free fatty acid.	tmpzr1t_l9r_go_relaxed.owl	VLDL remodeling|IDL formation|intermediate-density lipoprotein particle formation													biological_process											owl:Class	
GO:0075224	biolink:NamedThing	positive regulation of sporangium germination	Any process that activates, maintains or increases the frequency, rate or extent of sporangium germination.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of sporangium germination on or near host													biological_process											owl:Class	
GO:0007217	biolink:NamedThing	tachykinin receptor signaling pathway	The series of molecular signals generated as a consequence of a tachykinin, i.e. a short peptide with the terminal sequence (Phe-X-Gly-Leu-Met-NH2), binding to a cell surface receptor.	tmpzr1t_l9r_go_relaxed.owl	tachykinin signalling pathway													biological_process											owl:Class	
GO:0097199	biolink:NamedThing	cysteine-type endopeptidase activity involved in apoptotic signaling pathway	Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile, and contributing to the apoptotic signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	activator caspase activity|initiator caspase activity|cysteine-type endopeptidase activity involved in apoptotic signalling pathway|apical caspase activity					Examples of gene products that may be annotated to this term include CASP2, CASP8, CASP9, and CASP10, also called initiator (or apical, or activator) caspases.		pr	2011-12-12T01:43:00Z					molecular_function											owl:Class	
GO:1903761	biolink:NamedThing	negative regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization	Any process that stops, prevents or reduces the frequency, rate or extent of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of voltage gated potassium channel activity involved in ventricular cardiac muscle cell action potential|negative regulation of voltage-dependent potassium channel activity involved in ventricular cardiac muscle cell action potential|down regulation of voltage gated potassium channel activity involved in ventricular cardiac muscle cell action potential|down regulation of voltage-sensitive potassium channel involved in ventricular cardiac muscle cell action potential|down-regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization|negative regulation of voltage-gated potassium ion channel activity involved in ventricular cardiac muscle cell action potential|inhibition of voltage-sensitive potassium channel involved in ventricular cardiac muscle cell action potential|inhibition of voltage-gated potassium ion channel activity involved in ventricular cardiac muscle cell action potential|downregulation of voltage-dependent potassium channel activity involved in ventricular cardiac muscle cell action potential|down regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization|downregulation of voltage gated potassium channel activity involved in ventricular cardiac muscle cell action potential|down-regulation of voltage gated potassium channel activity involved in ventricular cardiac muscle cell action potential|negative regulation of voltage-sensitive potassium channel involved in ventricular cardiac muscle cell action potential|downregulation of voltage-gated potassium ion channel activity involved in ventricular cardiac muscle cell action potential|downregulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization|down regulation of voltage-gated potassium ion channel activity involved in ventricular cardiac muscle cell action potential|downregulation of voltage-sensitive potassium channel involved in ventricular cardiac muscle cell action potential|inhibition of voltage gated potassium channel activity involved in ventricular cardiac muscle cell action potential|down regulation of voltage-dependent potassium channel activity involved in ventricular cardiac muscle cell action potential|inhibition of voltage-dependent potassium channel activity involved in ventricular cardiac muscle cell action potential|inhibition of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization|down-regulation of voltage-dependent potassium channel activity involved in ventricular cardiac muscle cell action potential|down-regulation of voltage-gated potassium ion channel activity involved in ventricular cardiac muscle cell action potential|down-regulation of voltage-sensitive potassium channel involved in ventricular cardiac muscle cell action potential							rl	2014-12-19T12:02:09Z					biological_process											owl:Class	
GO:1902282	biolink:NamedThing	voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization	Enables the transmembrane transfer of a potassium ion by a voltage-gated channel through the plasma membrane of a ventricular cardiomyocyte contributing to the repolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.	tmpzr1t_l9r_go_relaxed.owl	voltage gated potassium channel activity involved in ventricular cardiac muscle cell action potential|voltage-sensitive potassium channel involved in ventricular cardiac muscle cell action potential|voltage-dependent potassium channel activity involved in ventricular cardiac muscle cell action potential|voltage-gated potassium ion channel activity involved in ventricular cardiac muscle cell action potential							rl	2013-07-05T20:12:22Z					molecular_function											owl:Class	
GO:0000027	biolink:NamedThing	ribosomal large subunit assembly	The aggregation, arrangement and bonding together of constituent RNAs and proteins to form the large ribosomal subunit.	tmpzr1t_l9r_go_relaxed.owl	50S ribosomal subunit assembly|60S ribosomal subunit assembly													biological_process											owl:Class	
GO:0042273	biolink:NamedThing	ribosomal large subunit biogenesis	A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a large ribosomal subunit; includes transport to the sites of protein synthesis.	tmpzr1t_l9r_go_relaxed.owl	ribosomal large subunit biogenesis and assembly													biological_process											owl:Class	
GO:1901406	biolink:NamedThing	positive regulation of tetrapyrrole catabolic process	Any process that activates or increases the frequency, rate or extent of tetrapyrrole catabolic process.	tmpzr1t_l9r_go_relaxed.owl	up regulation of tetrapyrrole catabolic process|activation of tetrapyrrole breakdown|positive regulation of tetrapyrrole breakdown|activation of tetrapyrrole catabolic process|upregulation of tetrapyrrole breakdown|activation of tetrapyrrole catabolism|up-regulation of tetrapyrrole degradation|activation of tetrapyrrole degradation|up-regulation of tetrapyrrole breakdown|upregulation of tetrapyrrole catabolism|up regulation of tetrapyrrole degradation|up-regulation of tetrapyrrole catabolism|upregulation of tetrapyrrole degradation|up regulation of tetrapyrrole breakdown|positive regulation of tetrapyrrole catabolism|upregulation of tetrapyrrole catabolic process|up regulation of tetrapyrrole catabolism|up-regulation of tetrapyrrole catabolic process|positive regulation of tetrapyrrole degradation							tt	2012-10-01T14:39:40Z					biological_process											owl:Class	
GO:0033015	biolink:NamedThing	tetrapyrrole catabolic process	The chemical reactions and pathways leading to the breakdown of tetrapyrroles, natural pigments containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next.	tmpzr1t_l9r_go_relaxed.owl	tetrapyrrole catabolism|tetrapyrrole degradation|tetrapyrrole breakdown													biological_process											owl:Class	
GO:2001017	biolink:NamedThing	regulation of retrograde axon cargo transport	Any process that modulates the frequency, rate or extent of retrograde axon cargo transport.	tmpzr1t_l9r_go_relaxed.owl	regulation of retrograde axonal transport							kmv	2011-08-11T09:44:42Z					biological_process											owl:Class	
GO:0021625	biolink:NamedThing	oculomotor nerve maturation	A developmental process, independent of morphogenetic (shape) change, that is required for the oculomotor nerve to attain its fully functional state. This motor nerve innervates all extraocular muscles except the superior oblique and the lateral rectus muscles. The superior division supplies the levator palpebrae superioris and superior rectus muscles. The inferior division supplies the medial rectus, inferior rectus and inferior oblique muscles. This nerve also innervates the striated muscles of the eyelid. Pupillary constriction and lens movement are mediated by this nerve for near vision. In the orbit the inferior division sends branches that enter the ciliary ganglion where they form functional contacts (synapses) with the ganglion cells. The ganglion cells send nerve fibers into the back of the eye where they travel to ultimately innervate the ciliary muscle and the constrictor pupillae muscle.	tmpzr1t_l9r_go_relaxed.owl	CN III maturation													biological_process											owl:Class	
GO:0021557	biolink:NamedThing	oculomotor nerve development	The process whose specific outcome is the progression of the oculomotor nerve over time, from its formation to the mature structure. This motor nerve innervates all extraocular muscles except the superior oblique and the lateral rectus muscles. The superior division supplies the levator palpebrae superioris and superior rectus muscles. The inferior division supplies the medial rectus, inferior rectus and inferior oblique muscles. This nerve also innervates the striated muscles of the eyelid. Pupillary constriction and lens movement are mediated by this nerve for near vision. In the orbit the inferior division sends branches that enter the ciliary ganglion where they form functional contacts (synapses) with the ganglion cells. The ganglion cells send nerve fibers into the back of the eye where they travel to ultimately innervate the ciliary muscle and the constrictor pupillae muscle.	tmpzr1t_l9r_go_relaxed.owl	cranial nerve III development|CN III development|cranial nerve 3 development													biological_process											owl:Class	
GO:0032724	biolink:NamedThing	positive regulation of fractalkine production	Any process that activates or increases the frequency, rate, or extent of fractalkine production.	tmpzr1t_l9r_go_relaxed.owl	upregulation of fractalkine production|up regulation of fractalkine production|up-regulation of fractalkine production|activation of fractalkine production|stimulation of fractalkine production													biological_process											owl:Class	
GO:0032603	biolink:NamedThing	fractalkine production	The appearance of fractalkine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	tmpzr1t_l9r_go_relaxed.owl	ABCD-3 production|CX3CL1 production|fractalkine metabolic process|fractalkine biosynthetic process|neurotactin production	https://github.com/geneontology/go-ontology/issues/19254										GO:0050754|GO:0050756|GO:0050751		biological_process											owl:Class	
GO:1902884	biolink:NamedThing	positive regulation of response to oxidative stress	Any process that activates or increases the frequency, rate or extent of response to oxidative stress.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of response to oxidative stress|up regulation of response to oxidative stress|activation of response to oxidative stress|upregulation of response to oxidative stress							kmv	2014-04-03T20:30:47Z					biological_process											owl:Class	
GO:0006979	biolink:NamedThing	response to oxidative stress	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1902020	biolink:NamedThing	negative regulation of cilium-dependent cell motility	Any process that stops, prevents or reduces the frequency, rate or extent of cilium-dependent cell motility.	tmpzr1t_l9r_go_relaxed.owl	downregulation of ciliary cell motility|down-regulation of ciliary cell motility|negative regulation of cilium cell motility|inhibition of ciliary cell motility|negative regulation of ciliary cell motility|down regulation of ciliary cell motility							jl	2013-03-27T14:42:42Z					biological_process											owl:Class	
GO:0070806	biolink:NamedThing	negative regulation of phialide development	Any process that stops, prevents, or reduces the frequency, rate or extent of phialide development, a process that leads to the formation of phialides. Phialides are specialized cells that bud from the ends of metulae on the conidiophore tip.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-07-08T04:47:16Z					biological_process											owl:Class	
GO:0070790	biolink:NamedThing	phialide development	The process whose specific outcome is the progression of phialides over time, from its formation to the mature structure. Phialides are specialized cells that bud from the ends of metulae on the conidiophore tip. Chains of conidia, or asexual spores, develop from the phialide tips.	tmpzr1t_l9r_go_relaxed.owl	development of secondary sterigmata							mah	2009-07-08T02:32:30Z					biological_process											owl:Class	
GO:0061117	biolink:NamedThing	negative regulation of heart growth	Any process that decreases the rate or extent of heart growth. Heart growth is the increase in size or mass of the heart.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-05-17T07:31:28Z					biological_process											owl:Class	
GO:1900887	biolink:NamedThing	regulation of pentadecane biosynthetic process	Any process that modulates the frequency, rate or extent of pentadecane biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of pentadecane synthesis|regulation of pentadecane biosynthesis|regulation of pentadecane formation|regulation of pentadecane anabolism							tt	2012-06-13T03:03:32Z					biological_process											owl:Class	
GO:1900634	biolink:NamedThing	pentadecane biosynthetic process	The chemical reactions and pathways resulting in the formation of pentadecane.	tmpzr1t_l9r_go_relaxed.owl	pentadecane anabolism|pentadecane biosynthesis|pentadecane formation|pentadecane synthesis							tt	2012-05-21T06:51:57Z					biological_process											owl:Class	
GO:1902031	biolink:NamedThing	regulation of NADP metabolic process	Any process that modulates the frequency, rate or extent of NADP metabolic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of NADP (reduced) metabolism|regulation of oxidized nicotinamide adenine dinucleotide phosphate metabolic process|regulation of NADP (oxidized) metabolism|regulation of NADPH metabolism|regulation of reduced NADP metabolic process|regulation of oxidized NADP metabolic process|regulation of NADP metabolism|regulation of reduced NADP metabolism|regulation of reduced nicotinamide adenine dinucleotide phosphate metabolism|regulation of reduced nicotinamide adenine dinucleotide phosphate metabolic process|regulation of oxidized NADP metabolism|regulation of nicotinamide adenine dinucleotide phosphate metabolic process|regulation of NADPH metabolic process|regulation of NADP (oxidized) metabolic process|regulation of NADP (reduced) metabolic process|regulation of nicotinamide adenine dinucleotide phosphate metabolism|regulation of NAD phosphorylation and dephosphorylation|regulation of oxidized nicotinamide adenine dinucleotide phosphate metabolism							jl	2013-03-28T20:21:48Z					biological_process											owl:Class	
GO:0021704	biolink:NamedThing	locus ceruleus morphogenesis	The process in which the anatomical structure of the locus ceruleus is generated and organized. In mice, the locus ceruleus is a dense cluster of neurons within the dorsorostral pons. This nucleus is the major location of neurons that release norepinephrine throughout the brain, and is responsible for physiological responses to stress and panic.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0090018	biolink:NamedThing	posterior neural plate formation	The formation of posterior end of the flat, thickened layer of ectodermal cells known as the neural plate.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-07-29T11:32:08Z					biological_process											owl:Class	
GO:0021990	biolink:NamedThing	neural plate formation	The formation of the flat, thickened layer of ectodermal cells known as the neural plate. The underlying dorsal mesoderm signals the ectodermal cells above it to elongate into columnar neural plate cells. The neural plate subsequently develops into the neural tube, which gives rise to the central nervous system.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0032901	biolink:NamedThing	positive regulation of neurotrophin production	Any process that activates or increases the frequency, rate, or extent of production of a neurotrophin.	tmpzr1t_l9r_go_relaxed.owl	up regulation of neurotrophin production|up-regulation of neurotrophin production|activation of neurotrophin production|stimulation of neurotrophin production|upregulation of neurotrophin production													biological_process											owl:Class	
GO:0097381	biolink:NamedThing	photoreceptor disc membrane	Stack of disc membranes located inside a photoreceptor outer segment, and containing densely packed molecules of photoreceptor proteins that traverse the lipid bilayer. Disc membranes arise as evaginations of the ciliary membrane during the development of the outer segment and may or may not remain contiguous with the ciliary membrane.	tmpzr1t_l9r_go_relaxed.owl								pr	2012-10-05T11:01:22Z					cellular_component											owl:Class	
GO:0001750	biolink:NamedThing	photoreceptor outer segment	The outer segment of a vertebrate photoreceptor that contains a stack of membrane discs embedded with photoreceptor proteins.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:1900688	biolink:NamedThing	positive regulation of gerfelin biosynthetic process	Any process that activates or increases the frequency, rate or extent of gerfelin biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	up regulation of gerfelin biosynthetic process|activation of gerfelin formation|up regulation of gerfelin formation|up regulation of gerfelin anabolism|upregulation of gerfelin biosynthetic process|upregulation of gerfelin biosynthesis|up-regulation of gerfelin synthesis|up-regulation of gerfelin biosynthesis|positive regulation of gerfelin biosynthesis|upregulation of gerfelin formation|activation of gerfelin synthesis|positive regulation of gerfelin formation|activation of gerfelin biosynthetic process|activation of gerfelin biosynthesis|up-regulation of gerfelin biosynthetic process|up regulation of gerfelin biosynthesis|up-regulation of gerfelin formation|up-regulation of gerfelin anabolism|positive regulation of gerfelin synthesis|upregulation of gerfelin synthesis|positive regulation of gerfelin anabolism|upregulation of gerfelin anabolism|activation of gerfelin anabolism|up regulation of gerfelin synthesis							di	2012-05-22T04:50:12Z					biological_process											owl:Class	
GO:1900578	biolink:NamedThing	gerfelin biosynthetic process	The chemical reactions and pathways resulting in the formation of gerfelin.	tmpzr1t_l9r_go_relaxed.owl	gerfelin biosynthesis|gerfelin synthesis|gerfelin formation|gerfelin anabolism							di	2012-05-15T06:42:47Z					biological_process											owl:Class	
GO:0070263	biolink:NamedThing	external side of fungal-type cell wall	The side of the fungal-type cell wall that is opposite to the side that faces the cell and its contents.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0009277	biolink:NamedThing	fungal-type cell wall	A rigid yet dynamic structure surrounding the plasma membrane that affords protection from stresses and contributes to cell morphogenesis, consisting of extensively cross-linked glycoproteins and carbohydrates. The glycoproteins may be modified with N- or O-linked carbohydrates, or glycosylphosphatidylinositol (GPI) anchors; the polysaccharides are primarily branched glucans, including beta-linked and alpha-linked glucans, and may also include chitin and other carbohydrate polymers, but not cellulose or pectin. Enzymes involved in cell wall biosynthesis are also found in the cell wall. Note that some forms of fungi develop a capsule outside of the cell wall under certain circumstances; this is considered a separate structure.	tmpzr1t_l9r_go_relaxed.owl	beta-glucan-containing cell wall|chitin- and beta-glucan-containing cell wall|chitin-containing cell wall													cellular_component											owl:Class	
GO:0009840	biolink:NamedThing	chloroplastic endopeptidase Clp complex	A Clp endopeptidase complex located in the chloroplast.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0009570	biolink:NamedThing	chloroplast stroma	The space enclosed by the double membrane of a chloroplast but excluding the thylakoid space. It contains DNA, ribosomes and some temporary products of photosynthesis.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:1900163	biolink:NamedThing	positive regulation of phospholipid scramblase activity	Any process that activates or increases the frequency, rate or extent of phospholipid scramblase activity.	tmpzr1t_l9r_go_relaxed.owl	activation of phospholipid scramblase activity|up regulation of phospholipid scramblase activity|up-regulation of phospholipid scramblase activity|upregulation of phospholipid scramblase activity							rph	2012-03-08T10:57:26Z					biological_process											owl:Class	
GO:0001936	biolink:NamedThing	regulation of endothelial cell proliferation	Any process that modulates the frequency, rate, or extent of endothelial cell proliferation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0001935	biolink:NamedThing	endothelial cell proliferation	The multiplication or reproduction of endothelial cells, resulting in the expansion of a cell population. Endothelial cells are thin flattened cells which line the inside surfaces of body cavities, blood vessels, and lymph vessels, making up the endothelium.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0005518	biolink:NamedThing	collagen binding	Binding to collagen, a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. Collagen is highly enriched in glycine (some regions are 33% glycine) and proline, occurring predominantly as 3-hydroxyproline (about 20%).	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0000466	biolink:NamedThing	maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	Any process involved in the maturation of an rRNA molecule originally produced as part of a tricistronic rRNA transcript that contained the Small SubUnit (SSU) rRNA, the 5.8S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1903803	biolink:NamedThing	L-glutamine import across plasma membrane	The directed movement of L-glutamine from outside of a cell, across the plasma membrane and into the cytosol.	tmpzr1t_l9r_go_relaxed.owl	L-glutamine import into cell|L-glutamine import|L-glutamine uptake							bf	2012-05-11T10:46:21Z			GO:0036229		biological_process											owl:Class	
GO:0090022	biolink:NamedThing	regulation of neutrophil chemotaxis	Any process that modulates the frequency, rate, or extent of neutrophil chemotaxis. Neutrophil chemotaxis is the directed movement of a neutrophil cell, the most numerous polymorphonuclear leukocyte found in the blood, in response to an external stimulus, usually an infection or wounding.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-08-03T10:09:34Z					biological_process											owl:Class	
GO:0009527	biolink:NamedThing	plastid outer membrane	The outer, i.e. cytoplasm-facing, lipid bilayer of the plastid envelope.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0060508	biolink:NamedThing	lung basal cell differentiation	The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features of a mature basal cell found in the lung. Differentiation includes the processes involved in commitment of a cell to a specific fate. A basal cell is an epithelial stem cell.	tmpzr1t_l9r_go_relaxed.owl	pulmonary basal cell differentiation													biological_process											owl:Class	
GO:0060428	biolink:NamedThing	lung epithelium development	The biological process whose specific outcome is the progression of the lung epithelium from an initial condition to its mature state. This process begins with the formation of lung epithelium and ends with the mature structure. The lung epithelium is the specialized epithelium that lines the inside of the lung.	tmpzr1t_l9r_go_relaxed.owl	pulmonary epithelium development													biological_process											owl:Class	
GO:0045893	biolink:NamedThing	positive regulation of transcription, DNA-templated	Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.	tmpzr1t_l9r_go_relaxed.owl	activation of gene-specific transcription|positive regulation of gene-specific transcription|upregulation of gene-specific transcription|stimulation of transcription, DNA-dependent|up regulation of transcription, DNA-dependent|up-regulation of transcription, DNA-dependent|up-regulation of gene-specific transcription|up regulation of gene-specific transcription|transcription activator activity|activation of transcription, DNA-dependent|upregulation of transcription, DNA-dependent|positive regulation of cellular transcription, DNA-dependent|stimulation of gene-specific transcription|positive regulation of transcription, DNA-dependent											GO:0043193|GO:0045941|GO:0061020		biological_process											owl:Class	
GO:0042025	biolink:NamedThing	host cell nucleus	A membrane-bounded organelle as it is found in the host cell in which chromosomes are housed and replicated. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl												GO:0033649		cellular_component											owl:Class	
GO:0031054	biolink:NamedThing	pre-miRNA processing	Any process involved in the conversion of a pre-microRNA transcript into a mature microRNA molecule.	tmpzr1t_l9r_go_relaxed.owl	pre-microRNA processing													biological_process											owl:Class	
GO:0099575	biolink:NamedThing	regulation of protein catabolic process at presynapse, modulating synaptic transmission	Any process that modulates synaptic transmission by regulating a catabolic process occurring at a presynapse.	tmpzr1t_l9r_go_relaxed.owl						Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.								biological_process											owl:Class	
GO:0002284	biolink:NamedThing	myeloid dendritic cell differentiation involved in immune response	The process in which an immature myeloid dendritic cell acquires the specialized features of a mature myeloid dendritic cell as part of an immune response.	tmpzr1t_l9r_go_relaxed.owl	myeloid dendritic cell differentiation during immune response													biological_process											owl:Class	
GO:0010467	biolink:NamedThing	gene expression	The process in which a gene's sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Gene_expression									biological_process											owl:Class	
GO:2000249	biolink:NamedThing	regulation of actin cytoskeleton reorganization	Any process that modulates the frequency, rate or extent of actin cytoskeleton reorganization.	tmpzr1t_l9r_go_relaxed.owl	regulation of actin cytoskeleton remodeling|regulation of actin cytoskeleton reorganisation							vk	2010-11-11T01:25:26Z					biological_process											owl:Class	
GO:0031532	biolink:NamedThing	actin cytoskeleton reorganization	A process that is carried out at the cellular level which results in dynamic structural changes to the arrangement of constituent parts of cytoskeletal structures comprising actin filaments and their associated proteins.	tmpzr1t_l9r_go_relaxed.owl	actin cytoskeleton remodeling|actin cytoskeleton reorganisation											GO:0007012		biological_process											owl:Class	
GO:0071607	biolink:NamedThing	macrophage inflammatory protein-1 gamma production	The appearance of macrophage inflammatory protein-1 gamma due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	tmpzr1t_l9r_go_relaxed.owl	CCL9 production|MIP-1g production|chemokine (C-C motif) ligand 9 production							mah	2010-02-05T04:19:52Z					biological_process											owl:Class	
GO:0032579	biolink:NamedThing	apical lamina of hyaline layer	A fibrous network that is part of the hyalin layer extracellular matrix. The apical lamina is thought to be principally composed of the glycoproteins fibropellins. This matrix has been found in echinoderms.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0033166	biolink:NamedThing	hyaline layer	A multilayered extraembryonic matrix that functions as a substrate for cell adhesion through early development. It is thought to protect and lubricate the embryo, stabilize the blastomeres during morphogenesis, and regulate nutrient intake. The major constituent of the hyaline layer is the protein hyalin. This matrix has been found in echinoderms.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0034750	biolink:NamedThing	Scrib-APC-beta-catenin complex	A protein complex that contains the Scribble protein (a cell polarity determinant), the tumor suppressor protein adenomatous polyposis coli (APC), and beta-catenin; may be involved in the control of cell proliferation.	tmpzr1t_l9r_go_relaxed.owl	hScrib-APC-beta-catenin complex					Note that the gene/protein name 'APC' should not be confused with the abbreviation for 'anaphase promoting complex'.								cellular_component											owl:Class	
GO:0048752	biolink:NamedThing	semicircular canal morphogenesis	The process in which the anatomical structures of the semicircular canals are generated and organized.	tmpzr1t_l9r_go_relaxed.owl	embryonic semicircular canal morphogenesis													biological_process											owl:Class	
GO:0015423	biolink:NamedThing	ABC-type maltose transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + maltose(out) = ADP + phosphate + maltose(in).	tmpzr1t_l9r_go_relaxed.owl	ATP-dependent maltose transmembrane transporter activity|maltose-transporting ATPase activity|maltose ABC transporter|maltooligosaccharide-importing ATPase activity|ABC-type maltose transporter|ATPase-coupled maltose transmembrane transporter activity				EC:7.5.2.1|RHEA:22132|MetaCyc:3.6.3.19-RXN									molecular_function											owl:Class	
GO:0060385	biolink:NamedThing	axonogenesis involved in innervation	The neurite development process that generates a long process of a neuron, as it invades a target tissue.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0072084	biolink:NamedThing	specification of distal tubule identity	The process in which the distal tubule of the kidney nephron acquires its identity.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-02-01T02:47:53Z					biological_process											owl:Class	
GO:0072156	biolink:NamedThing	distal tubule morphogenesis	The process in which the anatomical structures of a distal tubule are generated and organized. The distal tubule is a nephron tubule that begins at the macula densa and extends to the connecting tubule.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-02-24T02:32:03Z					biological_process											owl:Class	
GO:0031601	biolink:NamedThing	nuclear proteasome core complex	The core complex of a proteasome located in the nucleus of a cell.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0031595	biolink:NamedThing	nuclear proteasome complex	A proteasome found in the nucleus of a cell.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0072578	biolink:NamedThing	neurotransmitter-gated ion channel clustering	The receptor clustering process in which neurotransmitter-gated ion channels are localized to distinct domains in the cell membrane.	tmpzr1t_l9r_go_relaxed.owl								mah	2011-02-03T01:45:48Z					biological_process											owl:Class	
GO:0050808	biolink:NamedThing	synapse organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell).	tmpzr1t_l9r_go_relaxed.owl	synapse organisation|synapse organization and biogenesis|synapse development|synapse morphogenesis													biological_process											owl:Class	
GO:2000043	biolink:NamedThing	regulation of cardiac cell fate specification	Any process that modulates the frequency, rate or extent of cardiac cell fate specification.	tmpzr1t_l9r_go_relaxed.owl								tb	2010-08-19T09:01:04Z					biological_process											owl:Class	
GO:0060912	biolink:NamedThing	cardiac cell fate specification	The process involved in the specification of cardiac cell identity. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment.	tmpzr1t_l9r_go_relaxed.owl	cardiocyte cell fate specification							dph	2009-09-17T08:53:21Z					biological_process											owl:Class	
GO:0070779	biolink:NamedThing	D-aspartate import across plasma membrane	The directed import of D-aspartate from the extracellular region across the plasma membrane and into the cytosol.	tmpzr1t_l9r_go_relaxed.owl	D-aspartate import into cell|D-aspartate import|D-aspartate uptake							mah	2009-07-02T01:57:00Z			GO:0140016		biological_process											owl:Class	
GO:1905635	biolink:NamedThing	FACT complex assembly	The aggregation, arrangement and bonding together of a set of components to form a FACT complex.	tmpzr1t_l9r_go_relaxed.owl	Facilitates chromatin transcription complex assembly|FACT complex formation|Facilitates chromatin transcription complex formation							pga	2016-11-02T15:06:03Z					biological_process											owl:Class	
GO:0060433	biolink:NamedThing	bronchus development	The biological process whose specific outcome is the progression of a bronchus from an initial condition to its mature state. This process begins with the formation of the bronchus and ends with the mature structure. The bronchus is the portion of the airway that connects to the lungs.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0060541	biolink:NamedThing	respiratory system development	The progression of the respiratory system over time from its formation to its mature structure. The respiratory system carries out respiratory gaseous exchange.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-04-10T08:55:42Z					biological_process											owl:Class	
GO:0000308	biolink:NamedThing	cytoplasmic cyclin-dependent protein kinase holoenzyme complex	Cyclin-dependent protein kinase (CDK) complex found in the cytoplasm.	tmpzr1t_l9r_go_relaxed.owl	CDK holoenzyme													cellular_component											owl:Class	
GO:0008379	biolink:NamedThing	thioredoxin peroxidase activity	Catalysis of the reaction: thioredoxin + hydrogen peroxide = thioredoxin disulfide + H2O.	tmpzr1t_l9r_go_relaxed.owl	TrxPx activity|TPx activity|thiol peroxidase activity				MetaCyc:RXN0-267|Reactome:R-HSA-3322995|Reactome:R-HSA-2161612|RHEA:63528|Reactome:R-HSA-3697894|Reactome:R-HSA-3697882|Reactome:R-HSA-3341343							GO:0009031		molecular_function											owl:Class	
GO:0016560	biolink:NamedThing	protein import into peroxisome matrix, docking	The process in which a complex formed of a peroxisome targeting sequence (PTS) receptor bound to a PTS-bearing protein docks with translocation machinery in the peroxisomal membrane.	tmpzr1t_l9r_go_relaxed.owl	protein docking during protein import into peroxisome matrix|protein transport into peroxisome matrix, docking|peroxisome receptor docking|peroxisome matrix protein import, docking|protein docking during peroxisome matrix protein import|protein docking during protein transport into peroxisome matrix													biological_process											owl:Class	
GO:0051934	biolink:NamedThing	catecholamine uptake involved in synaptic transmission	The uptake of catecholamine neurotransmitters by neurons or glial cells. This process leads to inactivation and recycling of neurotransmitters.	tmpzr1t_l9r_go_relaxed.owl	catecholamine neurotransmitter import into glial cell|catecholamine neurotransmitter import into neuron|catecholamine uptake during transmission of nerve impulse|catecholamine neurotransmitter reuptake|catecholamine reuptake during transmission of nerve impulse|catecholamine neurotransmitter recycling													biological_process											owl:Class	
GO:0030894	biolink:NamedThing	replisome	A multi-component enzymatic machine at the replication fork which mediates DNA replication. Includes DNA primase, one or more DNA polymerases, DNA helicases, and other proteins.	tmpzr1t_l9r_go_relaxed.owl	DNA synthesome complex|RC complex|replication-competent complex				Wikipedia:Replisome									cellular_component											owl:Class	
GO:1990833	biolink:NamedThing	clathrin-uncoating ATPase activity	Catalysis of the reaction: ATP + H2O = ADP + phosphate. Catalysis of the removal of clathrin from vesicle membranes, coupled to the hydrolysis of ATP.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-08-21T18:01:42Z					molecular_function											owl:Class	
GO:0072318	biolink:NamedThing	clathrin coat disassembly	The disaggregation of a clathrin coat into its constituent components; results in stripping or removing the clathrin coat from clathrin-coated vesicles (CCV) before fusing with their targets. CVVs transport cargo from plasma membrane and trans-Golgi to the endosomal system.	tmpzr1t_l9r_go_relaxed.owl	clathrin-coat uncoating|clathrin-coat disassembly|clathrin-coated vesicle uncoating							mah	2010-10-26T12:03:37Z					biological_process											owl:Class	
GO:0010842	biolink:NamedThing	retina layer formation	The process in which the vertebrate retina is organized into three laminae: the outer nuclear layer (ONL), which contains photoreceptor nuclei; the inner nuclear layer (INL), which contains amacrine, bipolar and horizontal cells; and the retinal ganglion cell (RGC) layer. Between the inner and outer nuclear layers, the outer plexiform layer (OPL) contains connections between the photoreceptors and bipolar and horizontal cells. The inner plexiform layer (IPL) is positioned between the INL and the ganglion cell layer and contains the dendrites of RGCs and processes of bipolar and amacrine cells. Spanning all layers of the retina are the radially oriented Mueller glia.	tmpzr1t_l9r_go_relaxed.owl	retinal layer formation|retinal lamination													biological_process											owl:Class	
GO:0009908	biolink:NamedThing	flower development	The process whose specific outcome is the progression of the flower over time, from its formation to the mature structure. The flower is the reproductive structure in a plant, and its development begins with the transition of the vegetative or inflorescence meristem into a floral meristem.	tmpzr1t_l9r_go_relaxed.owl												GO:0048409		biological_process											owl:Class	
GO:0035886	biolink:NamedThing	vascular associated smooth muscle cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a vascular smooth muscle cell.	tmpzr1t_l9r_go_relaxed.owl	VSMC differentiation|vascular smooth muscle cell differentiation							bf	2011-06-08T11:23:52Z					biological_process											owl:Class	
GO:1990702	biolink:NamedThing	integral component of Golgi cis cisterna membrane	The component of the Golgi cis membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.	tmpzr1t_l9r_go_relaxed.owl	integral component of cis-Golgi cisterna membrane							bhm	2015-03-16T16:03:21Z					cellular_component											owl:Class	
GO:0086005	biolink:NamedThing	ventricular cardiac muscle cell action potential	An action potential that occurs in a ventricular cardiac muscle cell.	tmpzr1t_l9r_go_relaxed.owl								tb	2011-11-10T07:59:36Z					biological_process											owl:Class	
GO:0140256	biolink:NamedThing	negative regulation of cellular response to phosphate starvation	Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to phosphate starvation.	tmpzr1t_l9r_go_relaxed.owl								pg	2018-09-07T17:11:42Z					biological_process											owl:Class	
GO:0051885	biolink:NamedThing	positive regulation of timing of anagen	Any process that activates or increases the frequency, rate or extent of timing of anagen, the growth phase of the hair cycle.	tmpzr1t_l9r_go_relaxed.owl	upregulation of anagen|up-regulation of anagen|activation of anagen|positive regulation of anagen|stimulation of anagen|up regulation of anagen													biological_process											owl:Class	
GO:0042640	biolink:NamedThing	anagen	The growth phase of the hair cycle. Lasts, for example, about 3 to 6 years for human scalp hair.	tmpzr1t_l9r_go_relaxed.owl	hair growth					Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase. To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).								biological_process											owl:Class	
GO:0097723	biolink:NamedThing	amoeboid sperm motility	Any process involved in the controlled movement of an amoeboid sperm cell.	tmpzr1t_l9r_go_relaxed.owl	amoeboid sperm movement|ameboid sperm motility|ameboid sperm movement							pr	2016-09-01T12:02:19Z					biological_process											owl:Class	
GO:0042531	biolink:NamedThing	positive regulation of tyrosine phosphorylation of STAT protein	Any process that activates or increases the frequency, rate or extent of the introduction of a phosphate group to a tyrosine residue of a STAT (Signal Transducer and Activator of Transcription) protein.	tmpzr1t_l9r_go_relaxed.owl	upregulation of tyrosine phosphorylation of Stat4 protein|up regulation of tyrosine phosphorylation of Stat1 protein|activation of tyrosine phosphorylation of Stat5 protein|activation of tyrosine phosphorylation of Stat3 protein|positive regulation of tyrosine phosphorylation of Stat3 protein|stimulation of tyrosine phosphorylation of Stat1 protein|up regulation of tyrosine phosphorylation of STAT protein|upregulation of tyrosine phosphorylation of Stat3 protein|up-regulation of tyrosine phosphorylation of Stat1 protein|positive regulation of tyrosine phosphorylation of Stat2 protein|positive regulation of tyrosine phosphorylation of Stat6 protein|up regulation of tyrosine phosphorylation of Stat5 protein|upregulation of tyrosine phosphorylation of Stat6 protein|stimulation of tyrosine phosphorylation of Stat5 protein|up-regulation of tyrosine phosphorylation of Stat2 protein|up regulation of tyrosine phosphorylation of Stat4 protein|up-regulation of tyrosine phosphorylation of Stat3 protein|activation of tyrosine phosphorylation of Stat1 protein|activation of tyrosine phosphorylation of Stat7 protein|stimulation of tyrosine phosphorylation of Stat4 protein|stimulation of tyrosine phosphorylation of STAT protein|activation of tyrosine phosphorylation of Stat6 protein|up regulation of tyrosine phosphorylation of Stat2 protein|upregulation of tyrosine phosphorylation of Stat1 protein|up-regulation of tyrosine phosphorylation of Stat7 protein|up-regulation of tyrosine phosphorylation of Stat4 protein|upregulation of tyrosine phosphorylation of Stat2 protein|positive regulation of tyrosine phosphorylation of Stat1 protein|up-regulation of tyrosine phosphorylation of STAT protein|stimulation of tyrosine phosphorylation of Stat3 protein|stimulation of tyrosine phosphorylation of Stat7 protein|positive regulation of tyrosine phosphorylation of Stat4 protein|activation of tyrosine phosphorylation of Stat2 protein|positive regulation of tyrosine phosphorylation of Stat7 protein|positive regulation of tyrosine phosphorylation of Stat5 protein|stimulation of tyrosine phosphorylation of Stat6 protein|stimulation of tyrosine phosphorylation of Stat2 protein|upregulation of tyrosine phosphorylation of Stat5 protein|activation of tyrosine phosphorylation of STAT protein|up-regulation of tyrosine phosphorylation of Stat5 protein|upregulation of tyrosine phosphorylation of Stat7 protein|up-regulation of tyrosine phosphorylation of Stat6 protein|up regulation of tyrosine phosphorylation of Stat6 protein|up regulation of tyrosine phosphorylation of Stat3 protein|upregulation of tyrosine phosphorylation of STAT protein|activation of tyrosine phosphorylation of Stat4 protein|up regulation of tyrosine phosphorylation of Stat7 protein											GO:0042526|GO:0042517|GO:0042520|GO:0042529|GO:0042511|GO:0042515|GO:0042523		biological_process											owl:Class	
GO:0007260	biolink:NamedThing	tyrosine phosphorylation of STAT protein	The process of introducing a phosphate group to a tyrosine residue of a STAT (Signal Transducer and Activator of Transcription) protein.	tmpzr1t_l9r_go_relaxed.owl	tyrosine phosphorylation of Stat1 protein|tyrosine phosphorylation of Stat6 protein|tyrosine phosphorylation of Stat5 protein|tyrosine phosphorylation of Stat7 protein|tyrosine phosphorylation of Stat3 protein|tyrosine phosphorylation of Stat4 protein|tyrosine phosphorylation of Stat2 protein											GO:0042505|GO:0042502|GO:0042508|GO:0042506|GO:0042507|GO:0042504|GO:0042503		biological_process											owl:Class	
GO:0006407	biolink:NamedThing	rRNA export from nucleus	The directed movement of rRNA from the nucleus to the cytoplasm; the rRNA is usually in the form of ribonucleoproteins.	tmpzr1t_l9r_go_relaxed.owl	rRNA-nucleus export|rRNA transport from nucleus to cytoplasm|rRNA export out of nucleus|rRNA export from cell nucleus													biological_process											owl:Class	
GO:1902043	biolink:NamedThing	positive regulation of extrinsic apoptotic signaling pathway via death domain receptors	Any process that activates or increases the frequency, rate or extent of extrinsic apoptotic signaling pathway via death domain receptors.	tmpzr1t_l9r_go_relaxed.owl	up regulation of extrinsic apoptotic signaling pathway via death domain receptors|upregulation of death receptor-mediated apoptosis|up-regulation of extrinsic apoptotic signaling pathway via death domain receptors|positive regulation of death receptor-mediated apoptosis|activation of death receptor-mediated apoptosis|activation of extrinsic apoptotic signaling pathway via death domain receptors|up-regulation of death receptor-mediated apoptosis|upregulation of extrinsic apoptotic signaling pathway via death domain receptors|up regulation of death receptor-mediated apoptosis							lb	2013-04-03T07:17:11Z					biological_process											owl:Class	
GO:0008625	biolink:NamedThing	extrinsic apoptotic signaling pathway via death domain receptors	A series of molecular signals in which a signal is conveyed from the cell surface to trigger the apoptotic death of a cell. The pathway starts with a ligand binding to a death domain receptor on the cell surface, and ends when the execution phase of apoptosis is triggered.	tmpzr1t_l9r_go_relaxed.owl	induction of apoptosis via death receptors|death receptor-mediated apoptosis|induction of apoptosis via death domain receptors					Gene products that may be annotated to this term include: 1) ligands such as FASL; 2) receptors such as FAS/CD95 (though care should be taken because FAS can also act as a non-apoptotic signal transducer); 3) signaling molecules such as FADD (FAS-associated protein with a death domain), cIAPs (cellular inhibitor of apoptosis proteins), c-FLIPs and caspases 8 and 10. Examples are TWEAK (TNF12) and FN14 (TNFRSF12A) (UniProt symbols O43508 and Q9NP84) in PMID:21525013.								biological_process											owl:Class	
GO:2000625	biolink:NamedThing	regulation of miRNA catabolic process	Any process that modulates the frequency, rate or extent of miRNA catabolic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of microRNA catabolic process							dph	2011-04-18T03:46:35Z					biological_process											owl:Class	
GO:0010587	biolink:NamedThing	miRNA catabolic process	The chemical reactions and pathways resulting in the breakdown of miRNA, microRNA, a class of single-stranded RNA molecules of about 21-23 nucleotides in length, which regulates gene expression.	tmpzr1t_l9r_go_relaxed.owl	microRNA catabolic process													biological_process											owl:Class	
GO:0031236	biolink:NamedThing	extrinsic component of periplasmic side of plasma membrane	The component of a plasma membrane consisting of gene products and protein complexes that are loosely bound to its periplasmic surface, but not integrated into the hydrophobic region.	tmpzr1t_l9r_go_relaxed.owl	extrinsic to external side of plasma membrane, in periplasmic space|extrinsic to external leaflet of plasma membrane, in periplasmic space											GO:0031238		cellular_component											owl:Class	
GO:0007598	biolink:NamedThing	blood coagulation, extrinsic pathway	A protein activation cascade that contributes to blood coagulation and consists of the self-limited process linking exposure and activation of tissue factor to the activation of clotting factor X.	tmpzr1t_l9r_go_relaxed.owl						See also the biological process term 'blood coagulation, intrinsic pathway ; GO:0007597'.								biological_process											owl:Class	
GO:0005654	biolink:NamedThing	nucleoplasm	That part of the nuclear content other than the chromosomes or the nucleolus.	tmpzr1t_l9r_go_relaxed.owl					NIF_Subcellular:sao661522542|Wikipedia:Nucleoplasm									cellular_component											owl:Class	
GO:0003341	biolink:NamedThing	cilium movement	The directed, self-propelled movement of a cilium.	tmpzr1t_l9r_go_relaxed.owl	ciliary motility|flagellar motility|microtubule-based flagellum movement|cilium beating|flagellar movement|flagellum movement					Note that we deem cilium and microtubule-based flagellum to be equivalent.		dph	2009-11-24T09:56:26Z			GO:0036142		biological_process											owl:Class	
GO:0036470	biolink:NamedThing	tyrosine 3-monooxygenase activator activity	Interacts with and increases tyrosine 3-monooxygenase (tyrosine hydroxylase) activity.	tmpzr1t_l9r_go_relaxed.owl	TH activator activity|tyrosine hydroxylase activator activity							bf	2014-07-21T11:06:49Z					molecular_function											owl:Class	
GO:0007399	biolink:NamedThing	nervous system development	The process whose specific outcome is the progression of nervous tissue over time, from its formation to its mature state.	tmpzr1t_l9r_go_relaxed.owl	pan-neural process													biological_process											owl:Class	
GO:0072119	biolink:NamedThing	head kidney structural organization	The process that contributes to the act of creating the structural organization of the head kidney. This process pertains to the physical shaping of a rudimentary structure. The head kidney is a pronephros that consists of fused bilateral lobes located in the anterior part of the kidney.	tmpzr1t_l9r_go_relaxed.owl	head kidney structural organisation							mah	2010-02-22T11:22:12Z					biological_process											owl:Class	
GO:0072115	biolink:NamedThing	head kidney morphogenesis	The process in which the anatomical structures of the head kidney are generated and organized. The head kidney is a pronephros that consists of fused bilateral lobes located in the anterior part of the kidney.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-02-22T11:13:37Z					biological_process											owl:Class	
GO:0090729	biolink:NamedThing	toxin activity	Interacting selectively with one or more biological molecules in another (target) organism, initiating pathogenesis (leading to an abnormal, generally detrimental state) in the target organism. The activity should refer to an evolved function of the active gene product, i.e. one that was selected for. Examples include the activity of botulinum toxin, and snake venom.	tmpzr1t_l9r_go_relaxed.owl	toxin receptor binding				Wikipedia:Toxin			tb	2016-12-19T15:23:27Z			GO:0050827		molecular_function											owl:Class	
GO:2000511	biolink:NamedThing	regulation of granzyme A production	Any process that modulates the frequency, rate or extent of granzyme A production.	tmpzr1t_l9r_go_relaxed.owl								ebc	2011-03-22T10:31:27Z					biological_process											owl:Class	
GO:0035746	biolink:NamedThing	granzyme A production	The appearance of granzyme A due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	tmpzr1t_l9r_go_relaxed.owl						Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.		bf	2011-03-17T02:39:11Z					biological_process											owl:Class	
GO:0016056	biolink:NamedThing	rhodopsin mediated signaling pathway	The series of molecular signals generated as a consequence of excitation of rhodopsin by a photon and the events that convert the absorbed photons into a cellular response.	tmpzr1t_l9r_go_relaxed.owl	rhodopsin signaling|rhodopsin mediated phototransduction|rhodopsin mediated signalling pathway											GO:0009586		biological_process											owl:Class	
GO:0007603	biolink:NamedThing	phototransduction, visible light	The sequence of reactions within a cell required to convert absorbed photons from visible light into a molecular signal. A visible light stimulus is electromagnetic radiation that can be perceived visually by an organism; for organisms lacking a visual system, this can be defined as light with a wavelength within the range 380 to 780 nm.	tmpzr1t_l9r_go_relaxed.owl	visual cascade|visual transduction													biological_process											owl:Class	
GO:0030323	biolink:NamedThing	respiratory tube development	The process whose specific outcome is the progression of the respiratory tube over time, from its formation to the mature structure. The respiratory tube is assumed to mean any tube in the respiratory tract.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:2000015	biolink:NamedThing	regulation of determination of dorsal identity	Any process that modulates the frequency, rate or extent of determination of dorsal identity.	tmpzr1t_l9r_go_relaxed.owl	regulation of determination of adaxial identity							jl	2010-07-15T03:27:49Z					biological_process											owl:Class	
GO:0033024	biolink:NamedThing	mast cell apoptotic process	Any apoptotic process in a mast cell, a cell that is found in almost all tissues containing numerous basophilic granules and capable of releasing large amounts of histamine and heparin upon activation.	tmpzr1t_l9r_go_relaxed.owl	apoptosis of mast cells|mast cell apoptosis													biological_process											owl:Class	
GO:1902113	biolink:NamedThing	nucleotide phosphorylation involved in DNA repair	Any nucleotide phosphorylation that is involved in DNA repair.	tmpzr1t_l9r_go_relaxed.owl								al	2013-05-13T08:56:02Z					biological_process											owl:Class	
GO:0072195	biolink:NamedThing	kidney smooth muscle cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell in the kidney.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-03-01T02:07:52Z					biological_process											owl:Class	
GO:0110151	biolink:NamedThing	positive regulation of biomineralization	Any process that activates or increases the frequency, rate or extent of biomineralization, the formation and deposition of mineral crystals by living organisms.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of mineralization|positive regulation of mineralisation|positive regulation of biomineral formation|positive regulation of biomineralisation							kmv	2019-06-10T18:18:01Z					biological_process											owl:Class	
GO:0031848	biolink:NamedThing	protection from non-homologous end joining at telomere	A process that prevents non-homologous end joining at telomere, thereby ensuring that telomeres do not fuse.	tmpzr1t_l9r_go_relaxed.owl	protection from NHEJ-mediated telomere fusion													biological_process											owl:Class	
GO:1903888	biolink:NamedThing	regulation of plant epidermal cell differentiation	Any process that modulates the frequency, rate or extent of plant epidermal cell differentiation.	tmpzr1t_l9r_go_relaxed.owl								tb	2015-02-06T22:29:38Z					biological_process											owl:Class	
GO:0016517	biolink:NamedThing	interleukin-12 receptor activity	Combining with interleukin-12 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	IL-12 receptor activity|IL-12R													molecular_function											owl:Class	
GO:0035722	biolink:NamedThing	interleukin-12-mediated signaling pathway	A series of molecular signals initiated by the binding of interleukin-12 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.	tmpzr1t_l9r_go_relaxed.owl	interleukin-12-mediated signalling pathway|IL-12-mediated signaling pathway							bf	2011-03-07T11:27:58Z					biological_process											owl:Class	
GO:1904446	biolink:NamedThing	positive regulation of establishment of Sertoli cell barrier	Any process that activates or increases the frequency, rate or extent of establishment of Sertoli cell barrier.	tmpzr1t_l9r_go_relaxed.owl	upregulation of establishment of BTB|activation of establishment of SCB|up regulation of establishment of blood-testis barrier|up-regulation of establishment of Sertoli cell barrier|positive regulation of establishment of BTB|up-regulation of establishment of blood-testis barrier|positive regulation of establishment of blood-testis barrier|activation of establishment of BTB|up-regulation of establishment of SCB|upregulation of establishment of blood-testis barrier|upregulation of establishment of Sertoli cell barrier|up regulation of establishment of Sertoli cell barrier|upregulation of establishment of SCB|up regulation of establishment of BTB|activation of establishment of Sertoli cell barrier|up regulation of establishment of SCB|activation of establishment of blood-testis barrier|positive regulation of establishment of SCB|up-regulation of establishment of BTB							sl	2015-07-06T16:00:54Z					biological_process											owl:Class	
GO:0097368	biolink:NamedThing	establishment of Sertoli cell barrier	Establishment of a structure near the basement membrane in adjacent Sertoli cells of the seminiferous epithelium for maintaining spermatogenesis. The structure consists of tight junctions, basal ectoplasmic specializations, and desmosome-like junctions.	tmpzr1t_l9r_go_relaxed.owl	establishment of blood-testis barrier|establishment of SCB|establishment of BTB							pr	2012-08-02T17:05:55Z					biological_process											owl:Class	
GO:0062169	biolink:NamedThing	regulation of plus-end directed microtubule sliding	Any process that mediates the frequency, rate, or extent of plus-end directed microtubule sliding.	tmpzr1t_l9r_go_relaxed.owl								dph	2019-11-12T18:01:32Z					biological_process											owl:Class	
GO:0031535	biolink:NamedThing	plus-end directed microtubule sliding	The movement of one microtubule along another microtubule, where the motion is directed towards the plus ends of the microtubules.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0061169	biolink:NamedThing	positive regulation of hair placode formation	Any process that increases the rate, frequency, or extent of hair follicle placode formation, the developmental process in which a hair placode forms. An hair follicle placode is a thickening of the ectoderm that will give rise to the hair follicle bud.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-06-25T01:08:50Z					biological_process											owl:Class	
GO:0005635	biolink:NamedThing	nuclear envelope	The double lipid bilayer enclosing the nucleus and separating its contents from the rest of the cytoplasm; includes the intermembrane space, a gap of width 20-40 nm (also called the perinuclear space).	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Nuclear_envelope							GO:0005636		cellular_component											owl:Class	
GO:1903913	biolink:NamedThing	regulation of fusion of virus membrane with host plasma membrane	Any process that modulates the frequency, rate or extent of fusion of virus membrane with host plasma membrane.	tmpzr1t_l9r_go_relaxed.owl	regulation of viral entry into host cell via membrane fusion with the plasma membrane|regulation of viral envelope fusion with host plasma membrane|regulation of viral envelope fusion|regulation of viral-cell fusion molecule activity|regulation of viral envelope fusion with host membrane|regulation of viral envelope fusion with host cell membrane|regulation of viral penetration via membrane fusion							als	2015-02-09T11:13:19Z					biological_process											owl:Class	
GO:0005889	biolink:NamedThing	potassium:proton exchanging ATPase complex	A protein complex that possesses hydrogen:potassium-exchanging ATPase activity; characterized in animal cells, where it maintains ionic gradients of K+ at the expense of ATP hydrolysis; The complex contains two obligatory subunits, the catalytic alpha subunit and a glycosylated beta subunit; two additional subunits, gamma and channel-inducing factor (CHIF), may also be present.	tmpzr1t_l9r_go_relaxed.owl	proton pump|hydrogen/potassium-exchanging ATPase complex|hydrogen:potassium-exchanging ATPase complex													cellular_component											owl:Class	
GO:0003381	biolink:NamedThing	epithelial cell morphogenesis involved in gastrulation	The change in form that occurs when an epithelial cell progresses from it initial formation to its mature state, contributing to the process of gastrulation.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-12-09T07:18:53Z					biological_process											owl:Class	
GO:0035700	biolink:NamedThing	astrocyte chemotaxis	The directed movement of an astrocyte guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).	tmpzr1t_l9r_go_relaxed.owl								bf	2011-02-28T03:17:52Z					biological_process											owl:Class	
GO:0072264	biolink:NamedThing	metanephric glomerular endothelium development	The process whose specific outcome is the progression of the metanephric glomerular endothelium over time, from its formation to the mature structure. The metanephric glomerular endothelium is an epithelial tissue that covers the internal surfaces of the glomerulus of the metanephros.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-03-30T02:42:26Z					biological_process											owl:Class	
GO:0072239	biolink:NamedThing	metanephric glomerulus vasculature development	The biological process whose specific outcome is the progression of a metanephric glomerulus vasculature from an initial condition to its mature state. This process begins with the formation of the metanephric glomerulus vasculature and ends with the mature structure. The metanephric glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the metanephric glomerulus.	tmpzr1t_l9r_go_relaxed.owl	glomerulus capillary development							mah	2010-03-18T03:50:29Z					biological_process											owl:Class	
GO:0001844	biolink:NamedThing	protein insertion into mitochondrial membrane involved in apoptotic signaling pathway	The process in which a protein is incorporated into a mitochondrial membrane as the initial phase of the mitochondrial membrane permeabilization that takes place in the apoptotic signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	protein insertion into mitochondrial membrane involved in induction of apoptosis|protein insertion into mitochondrial membrane during induction of apoptosis|protein insertion into mitochondrion membrane during induction of apoptosis|insertion of proteins into mitochondrial membranes during the induction of apoptosis					Note that this term is intended to cover the insertion of pro-apoptotic proteins such as Bax or its homologs into mitochondrial membranes which occurs as an early step in the apoptotic program.								biological_process											owl:Class	
GO:0071921	biolink:NamedThing	cohesin loading	The protein localization to chromatin by which a cohesin ring complex is topologically linked to DNA.	tmpzr1t_l9r_go_relaxed.owl	cohesin localisation to chromatin|cohesin association with chromatin|cohesin localization to chromatin							mah	2010-09-28T11:07:26Z					biological_process											owl:Class	
GO:0045039	biolink:NamedThing	protein insertion into mitochondrial inner membrane	The processes mediating the insertion of proteins into the mitochondrial inner membrane. Mitochondrial inner membrane proteins can get inserted from the cytosol, by crossing the outer membrane and being guided by an inner membrane translocase complex into their final destination in the inner membrane. Some proteins present in the intermembrane space can get inserted into the inner mitochondrial membrane. Finally, some proteins are inserted into the inner membrane from the matrix side of the membrane.	tmpzr1t_l9r_go_relaxed.owl	protein import into mitochondrial inner membrane|mitochondrial inner membrane protein import|protein transport into mitochondrial inner membrane	https://github.com/geneontology/go-ontology/issues/15800												biological_process											owl:Class	
GO:0006626	biolink:NamedThing	protein targeting to mitochondrion	The process of directing proteins towards and into the mitochondrion, usually mediated by mitochondrial proteins that recognize signals contained within the imported protein.	tmpzr1t_l9r_go_relaxed.owl	protein-mitochondrial targeting|protein targeting to mitochondria|protein import into mitochondrion|mitochondrial translocation|mitochondrial protein import											GO:0043681		biological_process											owl:Class	
GO:0035688	biolink:NamedThing	T-helper 1 cell diapedesis	The passage of a T-helper 1 cell between the tight junctions of endothelial cells lining blood vessels, typically the fourth and final step of cellular extravasation. A T-helper 1 cell is a CD4-positive, alpha-beta T cell that has the phenotype T-bet-positive and produces interferon-gamma.	tmpzr1t_l9r_go_relaxed.owl	Th1 cell diapedesis							bf	2011-02-24T10:12:11Z					biological_process											owl:Class	
GO:0035687	biolink:NamedThing	T-helper 1 cell extravasation	The migration of a T-helper 1 cell from the blood vessels into the surrounding tissue. A T-helper 1 cell is a CD4-positive, alpha-beta T cell that has the phenotype T-bet-positive and produces interferon-gamma.	tmpzr1t_l9r_go_relaxed.owl	Th1 cell extravasation							bf	2011-02-24T10:10:00Z					biological_process											owl:Class	
GO:1905900	biolink:NamedThing	negative regulation of smooth muscle tissue development	Any process that stops, prevents or reduces the frequency, rate or extent of smooth muscle tissue development.	tmpzr1t_l9r_go_relaxed.owl	inhibition of smooth muscle tissue development|down regulation of smooth muscle tissue development|down-regulation of smooth muscle tissue development|downregulation of smooth muscle tissue development							bhm	2017-02-01T14:31:24Z					biological_process											owl:Class	
GO:0048745	biolink:NamedThing	smooth muscle tissue development	The process whose specific outcome is the progression of smooth muscle over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0016239	biolink:NamedThing	positive regulation of macroautophagy	Any process, such as recognition of nutrient depletion, that activates or increases the rate of macroautophagy to bring cytosolic macromolecules to the vacuole/lysosome for degradation.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of macroautophagy|activation of macroautophagy|positive regulation of starvation-induced autophagy|stimulation of macroautophagy|up regulation of macroautophagy|upregulation of macroautophagy													biological_process											owl:Class	
GO:0016255	biolink:NamedThing	attachment of GPI anchor to protein	A transamidation reaction that results in the cleavage of the polypeptide chain and the concomitant transfer of the GPI anchor to the newly formed carboxy-terminal amino acid of the anchored protein. The cleaved C-terminal contains the C-terminal GPI signal sequence of the newly synthesized polypeptide chain.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0045762	biolink:NamedThing	positive regulation of adenylate cyclase activity	Any process that activates or increases the frequency, rate or extent of adenylate cyclase activity.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of adenylyl cyclase activity|adenylate cyclase activator|up-regulation of adenylate cyclase activity|upregulation of adenylate cyclase activity|up regulation of adenylate cyclase activity|stimulation of adenylate cyclase activity													biological_process											owl:Class	
GO:0021877	biolink:NamedThing	forebrain neuron fate commitment	The process in which the developmental fate of a cell becomes restricted such that it will develop into a neuron that resides in the forebrain.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1904574	biolink:NamedThing	negative regulation of selenocysteine insertion sequence binding	Any process that stops, prevents or reduces the frequency, rate or extent of selenocysteine insertion sequence binding.	tmpzr1t_l9r_go_relaxed.owl	inhibition of SECIS binding|down-regulation of SECIS binding|down regulation of SECIS binding|downregulation of SECIS binding|negative regulation of SECIS binding|inhibition of selenocysteine insertion sequence binding|down regulation of selenocysteine insertion sequence binding|downregulation of selenocysteine insertion sequence binding|down-regulation of selenocysteine insertion sequence binding							sl	2015-08-19T17:51:15Z					biological_process											owl:Class	
GO:0090108	biolink:NamedThing	positive regulation of high-density lipoprotein particle assembly	Any process that increases the frequency, rate, or extent of high-density lipoprotein particle assembly. High-density lipoprotein particle assembly is the aggregation and arrangement of proteins and lipids to form a high-density lipoprotein particle.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-11-25T10:50:18Z					biological_process											owl:Class	
GO:0034380	biolink:NamedThing	high-density lipoprotein particle assembly	The non-covalent aggregation and arrangement of proteins and lipids to form a high-density lipoprotein particle.	tmpzr1t_l9r_go_relaxed.owl	HDL assembly													biological_process											owl:Class	
GO:0035017	biolink:NamedThing	cuticle pattern formation	The regionalization process that gives rise to the patterns of cell differentiation in the cuticle.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0042335	biolink:NamedThing	cuticle development	The chemical reactions and pathways resulting in the formation of a cuticle, the outer layer of some animals and plants, which acts to prevent water loss.	tmpzr1t_l9r_go_relaxed.owl	cuticle formation|cuticle synthesis|cuticle anabolism|cuticle biosynthesis|cuticle biosynthetic process													biological_process											owl:Class	
GO:1905260	biolink:NamedThing	positive regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway	Any process that activates or increases the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to nitrosative stress.	tmpzr1t_l9r_go_relaxed.owl	up regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway|up-regulation of nitrosative stress-induced apoptosis|activation of intrinsic apoptotic signaling pathway in response to nitrosative stress|upregulation of intrinsic apoptotic signaling pathway in response to nitrosative stress|up regulation of intrinsic apoptotic signaling pathway in response to nitrosative stress|up-regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway|positive regulation of nitrosative stress-induced apoptosis|up-regulation of intrinsic apoptotic signaling pathway in response to nitrosative stress|up regulation of nitrosative stress-induced apoptosis|upregulation of nitrosative stress-induced intrinsic apoptotic signaling pathway|activation of nitrosative stress-induced apoptosis|upregulation of nitrosative stress-induced apoptosis|activation of nitrosative stress-induced intrinsic apoptotic signaling pathway|positive regulation of intrinsic apoptotic signaling pathway in response to nitrosative stress							bf	2016-06-13T17:05:15Z					biological_process											owl:Class	
GO:2000334	biolink:NamedThing	positive regulation of blood microparticle formation	Any process that activates or increases the frequency, rate or extent of blood microparticle formation.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of microparticle generation|positive regulation of microparticle release							mah	2011-01-31T11:18:23Z					biological_process											owl:Class	
GO:0070816	biolink:NamedThing	phosphorylation of RNA polymerase II C-terminal domain	The process of introducing a phosphate group on to an amino acid residue in the C-terminal domain of RNA polymerase II. Typically, this occurs during the transcription cycle and results in production of an RNA polymerase II enzyme where the carboxy-terminal domain (CTD) of the largest subunit is extensively phosphorylated, often referred to as hyperphosphorylated or the II(0) form. Specific types of phosphorylation within the CTD are usually associated with specific regions of genes, though there are exceptions. The phosphorylation state regulates the association of specific complexes such as the capping enzyme or 3'-RNA processing machinery to the elongating RNA polymerase complex.	tmpzr1t_l9r_go_relaxed.owl	generation of II(0) form of RNA polymerase II|CTD domain phosphorylation of RNA polymerase II|hyperphosphorylation of RNA polymerase II C-terminal domain|generation of hyperphosphorylated CTD of RNA polymerase II							mah	2009-07-13T04:01:19Z			GO:0016245		biological_process											owl:Class	
GO:0048488	biolink:NamedThing	synaptic vesicle endocytosis	A vesicle-mediated transport process, in which the synaptic vesicle membrane constituents are retrieved from the presynaptic membrane on the axon terminal after neurotransmitter secretion by exocytosis. Synaptic vesicle endocytosis can occur via clathrin-dependent and clathrin-independent mechanisms.	tmpzr1t_l9r_go_relaxed.owl	synaptic vesicle retrieval	https://github.com/geneontology/synapse/issues/230										GO:0008099		biological_process											owl:Class	
GO:1902202	biolink:NamedThing	regulation of hepatocyte growth factor receptor signaling pathway	Any process that modulates the frequency, rate or extent of hepatocyte growth factor receptor signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	regulation of HGF receptor signalling pathway|regulation of Met signaling pathway|regulation of HGF receptor signaling pathway							lb	2013-06-10T13:20:45Z					biological_process											owl:Class	
GO:0048012	biolink:NamedThing	hepatocyte growth factor receptor signaling pathway	The series of molecular signals generated as a consequence of the hepatocyte growth factor receptor binding to one of its physiological ligands.	tmpzr1t_l9r_go_relaxed.owl	Met signaling pathway|HGF receptor signalling pathway|HGF receptor signaling pathway													biological_process											owl:Class	
GO:0002791	biolink:NamedThing	regulation of peptide secretion	Any process that modulates the frequency, rate, or extent of peptide secretion.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0009530	biolink:NamedThing	primary cell wall	A plant cell wall that is still able to expand, permitting cell growth. Primary cell walls contain more pectin than secondary walls and no lignin is present.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:1904742	biolink:NamedThing	regulation of telomeric DNA binding	Any process that modulates the frequency, rate or extent of telomeric DNA binding.	tmpzr1t_l9r_go_relaxed.owl	regulation of telomere binding|regulation of telomeric repeat binding							nc	2015-10-19T12:18:48Z					biological_process											owl:Class	
GO:0060810	biolink:NamedThing	intracellular mRNA localization involved in pattern specification process	Any process in which mRNA is transported to, or maintained in, a specific location within an oocyte that results in a pattern being established in the embryo.	tmpzr1t_l9r_go_relaxed.owl	intracellular mRNA localisation involved in pattern specification process							dph	2009-08-07T09:19:58Z					biological_process											owl:Class	
GO:1900914	biolink:NamedThing	regulation of octadecene biosynthetic process	Any process that modulates the frequency, rate or extent of octadecene biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of octadecene biosynthesis|regulation of octadecene formation|regulation of 1-octadecene biosynthetic process|regulation of octadecene synthesis|regulation of octadecene anabolism							tt	2012-06-13T04:24:24Z					biological_process											owl:Class	
GO:1900682	biolink:NamedThing	octadecene biosynthetic process	The chemical reactions and pathways resulting in the formation of octadecene.	tmpzr1t_l9r_go_relaxed.owl	octadecene synthesis|octadecene anabolism|octadecene biosynthesis|octadecene formation|1-octadecene biosynthetic process							tt	2012-05-22T04:28:49Z					biological_process											owl:Class	
GO:0061471	biolink:NamedThing	karyomere assembly	The process where the nuclear membrane engulfs condensed chromosomes to form karyomeres during M phase of the mitotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl								dph	2012-11-02T09:13:59Z					biological_process											owl:Class	
GO:0007084	biolink:NamedThing	mitotic nuclear membrane reassembly	The mitotic cell cycle process involving ESCRTIII that results in reformation of the nuclear envelope after mitotic nuclear division. In organisms undergoing closed mitosis this involves resealing or 'repair' of the nuclear envelope in the nuclear bridge.	tmpzr1t_l9r_go_relaxed.owl	nuclear envelope resealing|nuclear envelope repair|mitotic nuclear envelope reassembly	https://github.com/geneontology/go-ontology/issues/20636|https://github.com/geneontology/go-ontology/issues/19950												biological_process											owl:Class	
GO:0097252	biolink:NamedThing	oligodendrocyte apoptotic process	Any apoptotic process in an oligodendrocyte. Oligodendrocytes belong to a class of large neuroglial (macroglial) cells in the central nervous system, where they form the insulating myelin sheath of axons.	tmpzr1t_l9r_go_relaxed.owl	oligodendrocyte apoptosis							pr	2012-03-05T10:51:15Z					biological_process											owl:Class	
GO:0055117	biolink:NamedThing	regulation of cardiac muscle contraction	Any process that modulates the frequency, rate or extent of cardiac muscle contraction.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0060048	biolink:NamedThing	cardiac muscle contraction	Muscle contraction of cardiac muscle tissue.	tmpzr1t_l9r_go_relaxed.owl	heart muscle contraction													biological_process											owl:Class	
GO:0062194	biolink:NamedThing	cytoplasmic microtubule minus-end	A microtubule minus end that is part of a cytoplasmic microtubule.	tmpzr1t_l9r_go_relaxed.owl								dph	2019-12-09T19:06:36Z					cellular_component											owl:Class	
GO:0005881	biolink:NamedThing	cytoplasmic microtubule	Any microtubule in the cytoplasm of a cell.	tmpzr1t_l9r_go_relaxed.owl	non-spindle-associated astral microtubule													cellular_component											owl:Class	
GO:0021564	biolink:NamedThing	vagus nerve development	The process whose specific outcome is the progression of the vagus nerve over time, from its formation to the mature structure. This nerve is primarily sensory but also has visceromotor components. It originates in the brain stem and controls many autonomic functions of the heart, lungs, stomach, pharynx, larynx, trachea, esophagus and other gastrointestinal tract components. It controls some motor functions such as speech. The sensory branches mediate sensation from the pharynx, larynx, thorax and abdomen; it also innervates taste buds in the epiglottis.	tmpzr1t_l9r_go_relaxed.owl	cranial nerve 10 development|CN X development|cranial nerve X development													biological_process											owl:Class	
GO:0021783	biolink:NamedThing	preganglionic parasympathetic fiber development	The process whose specific outcome is the progression of a preganglionic parasympathetic fiber over time, from its formation to the mature structure. A preganglionic parasympathetic fiber is a cholinergic axonal fiber projecting from the CNS to a parasympathetic ganglion.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0060660	biolink:NamedThing	epidermis morphogenesis involved in nipple formation	The process in which the epidermis of the nipple sheath is uplifted to form an umbrella-like projection.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-05-29T11:04:04Z					biological_process											owl:Class	
GO:0060658	biolink:NamedThing	nipple morphogenesis	The process in which the nipple is generated and organized.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-05-29T10:45:44Z					biological_process											owl:Class	
GO:2000305	biolink:NamedThing	semaphorin-plexin signaling pathway involved in regulation of photoreceptor cell axon guidance	Any semaphorin-plexin signaling pathway that is involved in regulation of photoreceptor cell axon guidance.	tmpzr1t_l9r_go_relaxed.owl	semaphorin-plexin signalling pathway of regulation of photoreceptor cell axon pathfinding|semaphorin-plexin signaling pathway of regulation of photoreceptor cell axon guidance|semaphorin-plexin signaling pathway of regulation of photoreceptor cell axon pathfinding|semaphorin-plexin signalling pathway of regulation of photoreceptor cell axon guidance							sart	2011-01-07T01:42:34Z					biological_process											owl:Class	
GO:0090527	biolink:NamedThing	actin filament reorganization	A process that is carried out at the cellular level which results in dynamic structural changes to the arrangement of actin filaments.	tmpzr1t_l9r_go_relaxed.owl								tb	2013-01-23T10:27:44Z					biological_process											owl:Class	
GO:0036465	biolink:NamedThing	synaptic vesicle recycling	The trafficking of synaptic vesicles from the pre-synaptic membrane so the vesicle can dock and prime for another round of exocytosis and neurotransmitter release. Recycling occurs after synaptic vesicle exocytosis, and is necessary to replenish presynaptic vesicle pools, sustain transmitter release and preserve the structural integrity of the presynaptic membrane. Recycling can occur following transient fusion with the presynaptic membrane (kiss and run), or via endocytosis of presynaptic membrane.	tmpzr1t_l9r_go_relaxed.owl	kiss-and-run synaptic vesicle recycling|kiss-and-stay synaptic vesicle recycling							bf	2014-06-26T11:03:08Z					biological_process											owl:Class	
GO:0035813	biolink:NamedThing	regulation of renal sodium excretion	Any process that modulates the amount of sodium excreted in urine over a unit of time.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-04-20T01:26:30Z					biological_process											owl:Class	
GO:0035812	biolink:NamedThing	renal sodium excretion	The elimination by an organism of sodium in the urine.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-04-20T01:24:16Z					biological_process											owl:Class	
GO:0005095	biolink:NamedThing	GTPase inhibitor activity	Stops, prevents or reduces the activity of any enzyme that catalyzes the hydrolysis of GTP to GDP and orthophosphate.	tmpzr1t_l9r_go_relaxed.owl	GIP													molecular_function											owl:Class	
GO:1902029	biolink:NamedThing	positive regulation of histone H3-K18 acetylation	Any process that activates or increases the frequency, rate or extent of histone H3-K18 acetylation.	tmpzr1t_l9r_go_relaxed.owl	up regulation of histone H3 acetylation at K18|up-regulation of histone H3 acetylation at K18|activation of histone H3K18 acetylation|up-regulation of histone H3K18 acetylation|upregulation of histone H3 acetylation at K18|upregulation of histone H3K18 acetylation|up regulation of histone H3K18 acetylation|positive regulation of histone H3 acetylation at K18|up-regulation of histone H3-K18 acetylation|activation of histone H3 acetylation at K18|activation of histone H3-K18 acetylation|positive regulation of histone H3K18 acetylation|up regulation of histone H3-K18 acetylation|upregulation of histone H3-K18 acetylation							jl	2013-03-28T20:17:44Z					biological_process											owl:Class	
GO:0014718	biolink:NamedThing	positive regulation of satellite cell activation involved in skeletal muscle regeneration	Any process that activates, maintains or increases the frequency, rate or extent of activation of satellite cell involved in skeletal muscle regeneration. The activation of satellite cell is the process that initiates satellite cell division by causing it to move from quiescence to the G1 stage of the cell cycle. The cell swells and there are a number of other small changes. The cells then start to divide. Following cell division the cells will differentiate.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0014901	biolink:NamedThing	satellite cell activation involved in skeletal muscle regeneration	The process that initiates skeletal muscle satellite cell division by causing it to move from quiescence to the G1 stage of the cell cycle. The cell swells and there are a number of other small changes. The cells then start to divide. Following cell division the cells will differentiate. In adult muscle, satellite cells become activated to divide and differentiate in response to muscle damage.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0000289	biolink:NamedThing	nuclear-transcribed mRNA poly(A) tail shortening	Shortening of the poly(A) tail of a nuclear-transcribed mRNA from full length to an oligo(A) length.	tmpzr1t_l9r_go_relaxed.owl	nuclear mRNA poly(A) tail shortening|3' to 5' mRNA deadenylation|mRNA deadenylation													biological_process											owl:Class	
GO:0010856	biolink:NamedThing	adenylate cyclase activator activity	Increases the activity of the enzyme that catalyzes the reaction: ATP = 3',5'-cyclic AMP + diphosphate.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0004536	biolink:NamedThing	deoxyribonuclease activity	Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acid.	tmpzr1t_l9r_go_relaxed.owl	caspase-activated deoxyribonuclease activity				Reactome:R-HSA-6785986|Reactome:R-HSA-211247|Reactome:R-HSA-5685994							GO:0004537		molecular_function											owl:Class	
GO:0002031	biolink:NamedThing	G protein-coupled receptor internalization	The process that results in the uptake of a G protein-coupled receptor into an endocytic vesicle.	tmpzr1t_l9r_go_relaxed.owl	G-protein coupled receptor internalization													biological_process											owl:Class	
GO:0002029	biolink:NamedThing	desensitization of G protein-coupled receptor signaling pathway	The process that stops, prevents, or reduces the frequency, rate or extent of G protein-coupled receptor signaling pathway after prolonged stimulation with an agonist of the pathway.	tmpzr1t_l9r_go_relaxed.owl	desensitisation of G-protein coupled receptor protein signalling pathway|desensitization of G-protein coupled receptor protein signaling pathway													biological_process											owl:Class	
GO:0019058	biolink:NamedThing	viral life cycle	A set of processes which all viruses follow to ensure survival; includes attachment and entry of the virus particle, decoding of genome information, translation of viral mRNA by host ribosomes, genome replication, and assembly and release of viral particles containing the genome.	tmpzr1t_l9r_go_relaxed.owl	viral assembly, maturation, egress, and release|viral replication|viral infectious cycle|lytic viral life cycle											GO:0019067		biological_process											owl:Class	
GO:0036408	biolink:NamedThing	histone acetyltransferase activity (H3-K14 specific)	Catalysis of the reaction: acetyl-CoA + histone H3 L-lysine (position 14) = CoA + histone H3 N6-acetyl-L-lysine (position 14).	tmpzr1t_l9r_go_relaxed.owl	histone lysine N-acetyltransferase activity (H3-K14 specific)							bf	2013-08-21T10:03:10Z					molecular_function											owl:Class	
GO:0044154	biolink:NamedThing	histone H3-K14 acetylation	The modification of histone H3 by the addition of an acetyl group to a lysine residue at position 14 of the histone.	tmpzr1t_l9r_go_relaxed.owl	histone H3K14 acetylation|histone H3 acetylation at K14							jl	2009-08-11T03:40:43Z					biological_process											owl:Class	
GO:1901298	biolink:NamedThing	regulation of hydrogen peroxide-mediated programmed cell death	Any process that modulates the frequency, rate or extent of hydrogen peroxide-mediated programmed cell death.	tmpzr1t_l9r_go_relaxed.owl								vk	2012-08-21T09:44:59Z					biological_process											owl:Class	
GO:0010421	biolink:NamedThing	hydrogen peroxide-mediated programmed cell death	Programmed cell death induced by hydrogen peroxide. Programmed cell death is the cell death resulting from activation of endogenous cellular processes.	tmpzr1t_l9r_go_relaxed.owl	programmed cell death in response to hydrogen peroxide													biological_process											owl:Class	
GO:0015878	biolink:NamedThing	biotin transport	The directed movement of biotin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Biotin is cis-tetrahydro-2-oxothieno(3,4-d)imidazoline-4-valeric acid; the (+) enantiomer is very widely distributed in cells and serves as a carrier in a number of enzymatic beta-carboxylation reactions.	tmpzr1t_l9r_go_relaxed.owl	vitamin B7 transport|vitamin H transport													biological_process											owl:Class	
GO:0048840	biolink:NamedThing	otolith development	The process whose specific outcome is the progression of the otolith over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1903746	biolink:NamedThing	positive regulation of pharyngeal pumping	Any process that activates or increases the frequency, rate or extent of pharyngeal pumping.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of pumping behavior|up regulation of pumping behavior|up-regulation of pumping behavior|upregulation of pumping behavior|upregulation of pharyngeal pumping|activation of pumping behavior|up-regulation of pharyngeal pumping|activation of pharyngeal pumping|up regulation of pharyngeal pumping							kmv	2014-12-12T17:11:09Z					biological_process											owl:Class	
GO:0043050	biolink:NamedThing	pharyngeal pumping	The contraction and relaxation movements of the pharyngeal muscle that mediate feeding in nematodes.	tmpzr1t_l9r_go_relaxed.owl	pumping behavior													biological_process											owl:Class	
GO:0048890	biolink:NamedThing	lateral line ganglion development	The process whose specific outcome is the progression of the lateral line ganglion over time, from its formation to the mature structure. The lateral line ganglion develops from cranial ectodermal placodes situated between the eye and ear and behind the ear.	tmpzr1t_l9r_go_relaxed.owl	gLL ganglion development													biological_process											owl:Class	
GO:0000104	biolink:NamedThing	succinate dehydrogenase activity	Catalysis of the reaction: succinate + acceptor = fumarate + reduced acceptor.	tmpzr1t_l9r_go_relaxed.owl	succinate:acceptor oxidoreductase activity|fumarate reductase activity|succinic dehydrogenase activity|succinyl dehydrogenase activity|succinate:(acceptor) oxidoreductase activity|succinic acid dehydrogenase activity|fumaric hydrogenase activity|succinate oxidoreductase activity|succinodehydrogenase activity|fumarate dehydrogenase activity				MetaCyc:SUCC-FUM-OXRED-RXN|RHEA:16357							GO:0019739		molecular_function											owl:Class	
GO:1905569	biolink:NamedThing	negative regulation of ferrichrome biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of ferrichrome biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	downregulation of ferrichrome synthesis|negative regulation of ferrichrome synthesis|downregulation of ferrichrome biosynthetic process, peptide modification|down-regulation of ferrichrome formation|down regulation of ferrichrome biosynthetic process, peptide modification|downregulation of ferrichrome biosynthetic process|downregulation of ferrichrome anabolism|down regulation of ferrichrome formation|down-regulation of ferrichrome biosynthetic process, peptide modification|downregulation of ferrichrome biosynthesis|negative regulation of ferrichrome formation|down regulation of ferrichrome biosynthesis|down regulation of ferrichrome biosynthetic process, peptide formation|down regulation of ferrichrome anabolism|negative regulation of ferrichrome biosynthetic process, peptide formation|down regulation of ferrichrome synthesis|down-regulation of ferrichrome biosynthetic process, peptide formation|negative regulation of ferrichrome biosynthesis|down regulation of ferrichrome biosynthetic process|down-regulation of ferrichrome synthesis|inhibition of ferrichrome biosynthetic process, peptide modification|negative regulation of ferrichrome biosynthetic process, peptide modification|inhibition of ferrichrome formation|inhibition of ferrichrome anabolism|negative regulation of ferrichrome anabolism|down-regulation of ferrichrome biosynthesis|downregulation of ferrichrome formation|inhibition of ferrichrome biosynthetic process, peptide formation|inhibition of ferrichrome synthesis|inhibition of ferrichrome biosynthesis|down-regulation of ferrichrome biosynthetic process|downregulation of ferrichrome biosynthetic process, peptide formation|down-regulation of ferrichrome anabolism|inhibition of ferrichrome biosynthetic process							pr	2016-10-18T14:49:08Z					biological_process											owl:Class	
GO:1902203	biolink:NamedThing	negative regulation of hepatocyte growth factor receptor signaling pathway	Any process that stops, prevents or reduces the frequency, rate or extent of hepatocyte growth factor receptor signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of HGF receptor signaling pathway|inhibition of Met signaling pathway|down regulation of hepatocyte growth factor receptor signaling pathway|negative regulation of HGF receptor signaling pathway|down regulation of HGF receptor signaling pathway|inhibition of HGF receptor signalling pathway|negative regulation of Met signaling pathway|down regulation of Met signaling pathway|inhibition of HGF receptor signaling pathway|downregulation of Met signaling pathway|down-regulation of hepatocyte growth factor receptor signaling pathway|downregulation of HGF receptor signaling pathway|downregulation of hepatocyte growth factor receptor signaling pathway|down regulation of HGF receptor signalling pathway|down-regulation of Met signaling pathway|downregulation of HGF receptor signalling pathway|inhibition of hepatocyte growth factor receptor signaling pathway|down-regulation of HGF receptor signalling pathway|negative regulation of HGF receptor signalling pathway							lb	2013-06-10T13:20:51Z					biological_process											owl:Class	
GO:0070117	biolink:NamedThing	organellar chromatophore thylakoid lumen	The volume enclosed by an organellar chromatophore thylakoid membrane.	tmpzr1t_l9r_go_relaxed.owl	Paulinella-type chromatophore thylakoid lumen													cellular_component											owl:Class	
GO:0003199	biolink:NamedThing	endocardial cushion to mesenchymal transition involved in heart valve formation	A transition where an endocardial cushion cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell that will contribute to the formation of a cardiac valve.	tmpzr1t_l9r_go_relaxed.owl	endocardial cushion to mesenchymal transition involved in valve formation							dph	2009-10-08T01:31:21Z					biological_process											owl:Class	
GO:0043297	biolink:NamedThing	apical junction assembly	The formation of an apical junction, a functional unit located near the cell apex at the points of contact between epithelial cells composed of the tight junction, the zonula adherens junction and the desmosomes, by the aggregation, arrangement and bonding together of its constituents.	tmpzr1t_l9r_go_relaxed.owl	apical junction complex assembly													biological_process											owl:Class	
GO:0022034	biolink:NamedThing	rhombomere cell proliferation	The multiplication or reproduction of rhombomere cells, resulting in the expansion of the cell population.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0021546	biolink:NamedThing	rhombomere development	The process whose specific outcome is the progression of the rhombomere over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0043266	biolink:NamedThing	regulation of potassium ion transport	Any process that modulates the frequency, rate or extent of the directed movement of potassium ions (K+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	regulation of K+ transport|regulation of potassium ion conductance|regulation of potassium conductance|regulation of K+ conductance|regulation of potassium transport													biological_process											owl:Class	
GO:0006813	biolink:NamedThing	potassium ion transport	The directed movement of potassium ions (K+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	low voltage-dependent potassium channel auxiliary protein activity|potassium ion conductance|potassium conductance|K+ conductance|cellular potassium ion transport|sodium/potassium transport|potassium transport|low voltage-gated potassium channel auxiliary protein activity							mah	2010-09-03T02:39:22Z			GO:0015458|GO:0071804		biological_process											owl:Class	
GO:0032953	biolink:NamedThing	regulation of (1->3)-beta-D-glucan biosynthetic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans.	tmpzr1t_l9r_go_relaxed.owl	regulation of 1,3-beta-glucan biosynthesis|regulation of 1,3-beta-glucan biosynthetic process|regulation of 1,3-beta-glucan anabolism|regulation of 1,3-beta-glucan synthesis|regulation of 1,3-beta-glucan formation													biological_process											owl:Class	
GO:0006075	biolink:NamedThing	(1->3)-beta-D-glucan biosynthetic process	The chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds.	tmpzr1t_l9r_go_relaxed.owl	1,3-beta-glucan synthesis|beta-1,3 glucan anabolism|beta-1,3 glucan biosynthetic process|1,3-beta-glucan formation|beta-1,3 glucan synthesis|1,3-beta-glucan biosynthesis|1,3-beta-glucan anabolism|beta-1,3 glucan formation|1,3-beta-D-glucan biosynthetic process|beta-1,3 glucan biosynthesis													biological_process											owl:Class	
GO:0032622	biolink:NamedThing	interleukin-19 production	The appearance of interleukin-19 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	tmpzr1t_l9r_go_relaxed.owl	IL-19 production|interleukin-19 secretion|IL-19 secretion|ZMDA1 secretion|interleukin-19 biosynthetic process											GO:0042236|GO:0072617		biological_process											owl:Class	
GO:0033520	biolink:NamedThing	phytol biosynthetic process	The chemical reactions and pathways resulting in the formation of phytol, (2E,7R,11R)-3,7,11,15-tetramethylhexadec-2-en-1-ol.	tmpzr1t_l9r_go_relaxed.owl	phytol formation|phytol biosynthesis|phytol synthesis|phytol anabolism													biological_process											owl:Class	
GO:1901453	biolink:NamedThing	positive regulation of response to benzene	Any process that activates or increases the frequency, rate or extent of response to benzene.	tmpzr1t_l9r_go_relaxed.owl	activation of response to benzene|up regulation of response to benzene|up-regulation of response to benzene|upregulation of response to benzene							tt	2012-10-02T14:20:41Z					biological_process											owl:Class	
GO:1901423	biolink:NamedThing	response to benzene	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a benzene stimulus.	tmpzr1t_l9r_go_relaxed.owl								tt	2012-10-01T18:35:11Z					biological_process											owl:Class	
GO:0098856	biolink:NamedThing	intestinal lipid absorption	Any process in which lipids are taken up from the contents of the intestine.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0120003	biolink:NamedThing	hinge region between urothelial plaques of apical plasma membrane	A narrow rim of non-thickened membrane in between urothelial plaques in apical plasma membrane.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/12996						krc	2017-02-23T22:13:27Z					cellular_component											owl:Class	
GO:0016324	biolink:NamedThing	apical plasma membrane	The region of the plasma membrane located at the apical end of the cell.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0051200	biolink:NamedThing	positive regulation of prosthetic group metabolic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a prosthetic group.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of prosthetic group metabolism|positive regulation of coenzyme and prosthetic group metabolism|stimulation of prosthetic group metabolic process|activation of prosthetic group metabolic process|positive regulation of coenzyme and prosthetic group metabolic process|up-regulation of prosthetic group metabolic process|up regulation of prosthetic group metabolic process|upregulation of prosthetic group metabolic process													biological_process											owl:Class	
GO:0010026	biolink:NamedThing	trichome differentiation	The process in which a relatively unspecialized epidermal cell acquires the specialized features of a trichome cell. An example of this process is found in Arabidopsis thaliana.	tmpzr1t_l9r_go_relaxed.owl	trichome cell differentiation											GO:0048271		biological_process											owl:Class	
GO:0090558	biolink:NamedThing	plant epidermis development	The process whose specific outcome is the progression of the plant epidermis over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl								tb	2014-02-27T15:17:37Z					biological_process											owl:Class	
GO:1903975	biolink:NamedThing	regulation of glial cell migration	Any process that modulates the frequency, rate or extent of glial cell migration.	tmpzr1t_l9r_go_relaxed.owl	regulation of glia cell migration							nc	2015-03-02T15:13:31Z					biological_process											owl:Class	
GO:0031088	biolink:NamedThing	platelet dense granule membrane	The lipid bilayer surrounding the platelet dense granule.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0005765	biolink:NamedThing	lysosomal membrane	The lipid bilayer surrounding the lysosome and separating its contents from the cell cytoplasm.	tmpzr1t_l9r_go_relaxed.owl	lysosome membrane													cellular_component											owl:Class	
GO:0060276	biolink:NamedThing	maintenance of stationary phase in response to toxin	The homeostatic process in which a population of cells changes its metabolic activity resulting in the rate of death in the population equaling the rate of reproduction in response to a build-up of toxins in the environment.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1902428	biolink:NamedThing	negative regulation of water channel activity	Any process that stops, prevents or reduces the frequency, rate or extent of water channel activity.	tmpzr1t_l9r_go_relaxed.owl	down regulation of aquaporin|down regulation of water channel activity|inhibition of aquaporin|negative regulation of aquaporin|downregulation of water channel activity|down-regulation of aquaporin|down-regulation of water channel activity|inhibition of water channel activity|downregulation of aquaporin							bf	2013-09-23T12:56:40Z					biological_process											owl:Class	
GO:0015250	biolink:NamedThing	water channel activity	Transport systems of this type enable facilitated diffusion of water (by an energy-independent process) by passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.	tmpzr1t_l9r_go_relaxed.owl	aquaporin				Reactome:R-HSA-445714|Reactome:R-HSA-507870|Reactome:R-HSA-432065|Reactome:R-HSA-432010|RHEA:29667|Reactome:R-HSA-432067|Reactome:R-HSA-507868|Reactome:R-HSA-432054									molecular_function											owl:Class	
GO:0032588	biolink:NamedThing	trans-Golgi network membrane	The lipid bilayer surrounding any of the compartments that make up the trans-Golgi network.	tmpzr1t_l9r_go_relaxed.owl	trans Golgi network membrane|Golgi trans face membrane													cellular_component											owl:Class	
GO:0005802	biolink:NamedThing	trans-Golgi network	The network of interconnected tubular and cisternal structures located within the Golgi apparatus on the side distal to the endoplasmic reticulum, from which secretory vesicles emerge. The trans-Golgi network is important in the later stages of protein secretion where it is thought to play a key role in the sorting and targeting of secreted proteins to the correct destination.	tmpzr1t_l9r_go_relaxed.owl	Golgi trans face|maturing face|trans face|TGN|trans Golgi network|Golgi trans-face|late Golgi				NIF_Subcellular:sao9456487	There are different opinions about whether the TGN should be considered part of the Golgi apparatus or not.  We follow Alberts et al, 1994 (ISBN:0815316194), who consider it to be a part.								cellular_component											owl:Class	
GO:0042790	biolink:NamedThing	nucleolar large rRNA transcription by RNA polymerase I	The synthesis of the large ribosomal RNA (rRNA) transcript which encodes several rRNAs, e.g. in mammals 28S, 18S and 5.8S, from a nuclear DNA template transcribed by RNA polymerase I.	tmpzr1t_l9r_go_relaxed.owl	transcription of nuclear large rRNA transcript from RNA polymerase I promoter|transcription of nucleolar large rRNA by RNA polymerase I|transcription of nuclear rRNA large Pol I transcript	https://github.com/geneontology/go-ontology/issues/14854												biological_process											owl:Class	
GO:2000886	biolink:NamedThing	glucuronoxylan catabolic process	The chemical reactions and pathways resulting in the breakdown of a glucuronoxylan.	tmpzr1t_l9r_go_relaxed.owl	glucuronoxylan catabolism							jl	2011-07-28T09:37:06Z					biological_process											owl:Class	
GO:0019914	biolink:NamedThing	cyclin-dependent protein kinase activating kinase regulator activity	Modulation of the activity of the enzyme cyclin-dependent protein kinase activating kinase.	tmpzr1t_l9r_go_relaxed.owl	cyclin-dependent protein kinase activating kinase, intrinsic regulator activity				EC:2.7.1.-									molecular_function											owl:Class	
GO:1904541	biolink:NamedThing	fungal-type cell wall disassembly involved in conjugation with cellular fusion	Any fungal-type cell wall disassembly that is involved in conjugation with cellular fusion.	tmpzr1t_l9r_go_relaxed.owl	fungal-type cell wall disassembly involved in mating|fungal-type cell wall disassembly involved in cell fusion							al	2015-08-10T17:12:51Z					biological_process											owl:Class	
GO:0071341	biolink:NamedThing	medial cortical node	A component of the cell division site that contains the mid1, cdr2, wee1, klp8, and blt1 proteins, and is involved in contractile ring localization. Medial cortical node complexes appear as cortical dots in the middle of the cell during interphase, and function to recruit other ring components in early mitosis.	tmpzr1t_l9r_go_relaxed.owl	mid1p medial cortical dot|midsome							mah	2009-12-11T11:40:36Z					cellular_component											owl:Class	
GO:0031097	biolink:NamedThing	medial cortex	A medial cortical band overlaying the nucleus which acts as a landmark for contractile ring positioning and plays a role in cell cycle regulation.	tmpzr1t_l9r_go_relaxed.owl	medial ring													cellular_component											owl:Class	
GO:2000178	biolink:NamedThing	negative regulation of neural precursor cell proliferation	Any process that stops, prevents, or reduces the frequency, rate or extent of neural precursor cell proliferation.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-10-13T12:40:43Z					biological_process											owl:Class	
GO:0075323	biolink:NamedThing	positive regulation of oomycete sporangium development	Any process that activates, maintains or increases the frequency, rate or extent of oomycete sporangium development, a process that leads to the formation of oomycete sporangium, a single-celled or many-celled structure that germinates directly to form an infection hypha or differentiate, through specialized cleavage vesicles, into between 10 and 30 zoospores, which is laterally flagellated.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0031098	biolink:NamedThing	stress-activated protein kinase signaling cascade	A series of molecular signals in which a stress-activated protein kinase (SAPK) cascade relays one or more of the signals.	tmpzr1t_l9r_go_relaxed.owl	JNK signalling pathway|JNK signaling pathway|SAPK signalling pathway|SAPK signaling pathway|stress-activated protein kinase signaling pathway|stress-activated protein kinase signalling pathway													biological_process											owl:Class	
GO:0032280	biolink:NamedThing	symmetric synapse	A synapse that lacks an electron dense postsynaptic specialization. In vertebtrates, these occur primarily on dendrite shafts and neuronal cell bodies and involve persynapses containing clusters of predominantly flattened or elongated vesicles and are typcially inhibitory.	tmpzr1t_l9r_go_relaxed.owl	Gray's type II synapse					The term 'symmetric' in this name refers only to gross morphology.  There is no implication of functional symmetry.								cellular_component											owl:Class	
GO:1904718	biolink:NamedThing	negative regulation of AMPA glutamate receptor clustering	Any process that stops, prevents or reduces the frequency, rate or extent of AMPA glutamate receptor clustering.	tmpzr1t_l9r_go_relaxed.owl	inhibition of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor clustering|down regulation of AMPA receptor clustering|downregulation of AMPA receptor clustering|down-regulation of AMPA glutamate receptor clustering|inhibition of AMPA receptor clustering|down regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor clustering|down-regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor clustering|downregulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor clustering|negative regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor clustering|down regulation of AMPA glutamate receptor clustering|down-regulation of AMPA receptor clustering|downregulation of AMPA glutamate receptor clustering|inhibition of AMPA glutamate receptor clustering|negative regulation of AMPA receptor clustering							hjd	2015-10-07T19:32:28Z					biological_process											owl:Class	
GO:0097113	biolink:NamedThing	AMPA glutamate receptor clustering	The glutamate receptor clustering process in which alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptors are localized to distinct domains in the cell membrane.	tmpzr1t_l9r_go_relaxed.owl	AMPA receptor clustering|alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor clustering							pr	2011-07-31T05:25:53Z					biological_process											owl:Class	
GO:0060888	biolink:NamedThing	limb epidermis stratification	The pattern specification process that results in the subdivision of the epidermis of the limb in space to define a volume in which specific patterns of basal cell, spinous cell and granular cells will differentiate giving rise to the layers of the limb epidermis.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-08-13T12:45:48Z					biological_process											owl:Class	
GO:0006489	biolink:NamedThing	dolichyl diphosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of dolichyl diphosphate, a diphosphorylated dolichol derivative.	tmpzr1t_l9r_go_relaxed.owl	dolichyl diphosphate biosynthesis|dolichyl diphosphate formation|dolichyl diphosphate anabolism|dolichyl diphosphate synthesis													biological_process											owl:Class	
GO:0006488	biolink:NamedThing	dolichol-linked oligosaccharide biosynthetic process	The chemical reactions and pathways resulting in the formation of dolichol-linked oligosaccharide, usually by a stepwise addition of glycosyl chains to endoplasmic reticulum membrane-bound dolichol-P.	tmpzr1t_l9r_go_relaxed.owl	dolichol-linked oligosaccharide anabolism|dolichol-linked oligosaccharide biosynthesis|dolichol-linked oligosaccharide formation|oligosaccharide-PP-dolichol assembly|N-linked glycan precursor biosynthetic process|N-linked glycan precursor biosynthesis|dolichol-linked oligosaccharide synthesis													biological_process											owl:Class	
GO:1900653	biolink:NamedThing	negative regulation of demethylkotanin biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of demethylkotanin biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	down regulation of demethylkotanin synthesis|downregulation of demethylkotanin anabolism|down-regulation of demethylkotanin synthesis|down-regulation of demethylkotanin biosynthetic process|down regulation of demethylkotanin biosynthetic process|inhibition of demethylkotanin biosynthetic process|negative regulation of demethylkotanin synthesis|down-regulation of demethylkotanin anabolism|inhibition of demethylkotanin anabolism|down-regulation of demethylkotanin formation|inhibition of demethylkotanin synthesis|down regulation of demethylkotanin anabolism|inhibition of demethylkotanin formation|downregulation of demethylkotanin biosynthesis|down-regulation of demethylkotanin biosynthesis|negative regulation of demethylkotanin formation|downregulation of demethylkotanin synthesis|downregulation of demethylkotanin formation|inhibition of demethylkotanin biosynthesis|down regulation of demethylkotanin biosynthesis|negative regulation of demethylkotanin biosynthesis|downregulation of demethylkotanin biosynthetic process|down regulation of demethylkotanin formation|negative regulation of demethylkotanin anabolism							di	2012-05-22T04:07:41Z					biological_process											owl:Class	
GO:1900599	biolink:NamedThing	demethylkotanin biosynthetic process	The chemical reactions and pathways resulting in the formation of demethylkotanin.	tmpzr1t_l9r_go_relaxed.owl	demethylkotanin biosynthesis|demethylkotanin synthesis|demethylkotanin formation|demethylkotanin anabolism							di	2012-05-15T06:55:21Z					biological_process											owl:Class	
GO:0007299	biolink:NamedThing	ovarian follicle cell-cell adhesion	The attachment of a somatic follicle cell to another somatic follicle cell or to its substratum, the germline cells. An example of this is found in Drosophila melanogaster.	tmpzr1t_l9r_go_relaxed.owl	follicle cell adhesion|ovarian follicle cell adhesion													biological_process											owl:Class	
GO:0034095	biolink:NamedThing	negative regulation of maintenance of meiotic sister chromatid cohesion	Any process that decreases the extent to which the association between sister chromatids of a replicated chromosome is maintained during a meiotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0098837	biolink:NamedThing	postsynaptic recycling endosome	A recycling endosome of the postsynapse. In postsynaptic terminals with dendritic spines, it is typically located at the base of a dendritic spine. It is involved in recycling of neurotransmitter receptors to the postsynaptic membrane.  In some cases at least, this recycling is activated by postsynaptic signalling and so can play a role in long term potentiation.	tmpzr1t_l9r_go_relaxed.owl	postsynaptic endosomal recycling compartment|postsynaptic recycling outpost													cellular_component											owl:Class	
GO:0031649	biolink:NamedThing	heat generation	Any homeostatic process in which an organism produces heat, thereby raising its internal temperature.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:2000772	biolink:NamedThing	regulation of cellular senescence	Any process that modulates the frequency, rate or extent of cellular senescence.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-06-22T01:57:04Z					biological_process											owl:Class	
GO:0110025	biolink:NamedThing	DNA strand resection involved in replication fork processing	The 5' to 3' exonucleolytic resection of DNA at the site of a stalled replication fork that contributes to replication fork processing.	tmpzr1t_l9r_go_relaxed.owl								kmv	2017-07-05T14:43:36Z					biological_process											owl:Class	
GO:0032007	biolink:NamedThing	negative regulation of TOR signaling	Any process that stops, prevents, or reduces the frequency, rate or extent of TOR signaling.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of TOR signaling cascade|negative regulation of TOR signaling pathway|down-regulation of TOR signaling pathway|down regulation of TOR signaling pathway|negative regulation of target of rapamycin signaling pathway|negative regulation of TOR signalling pathway|downregulation of TOR signaling pathway|negative regulation of target of rapamycin signalling pathway|inhibition of TOR signaling pathway													biological_process											owl:Class	
GO:0031929	biolink:NamedThing	TOR signaling	A series of molecular signals mediated by TOR (Target of rapamycin) proteins, members of the phosphoinositide (PI) 3-kinase related kinase (PIKK) family that act as serine/threonine kinases in response to nutrient availability or growth factors.	tmpzr1t_l9r_go_relaxed.owl	TOR signaling pathway|TOR signal transduction|target of rapamycin signalling pathway|TOR signaling cascade|target of rapamycin signaling pathway|TOR signalling pathway					Note that this term should not be confused with 'torso signaling pathway ; GO:0008293', although torso is abbreviated 'tor'.								biological_process											owl:Class	
GO:0033146	biolink:NamedThing	regulation of intracellular estrogen receptor signaling pathway	Any process that modulates the frequency, rate or extent of the activity of an intracellular estrogen receptor signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	regulation of estrogen receptor signalling pathway|regulation of estrogen receptor signaling pathway													biological_process											owl:Class	
GO:0030520	biolink:NamedThing	intracellular estrogen receptor signaling pathway	Any series of molecular signals generated as a consequence of an intracellular estrogen receptor binding to one of its physiological ligands. The pathway begins with receptor-ligand binding, and ends with regulation of a downstream cellular process (e.g. transcription).	tmpzr1t_l9r_go_relaxed.owl	estrogen receptor signaling pathway|estrogen receptor signalling pathway													biological_process											owl:Class	
GO:0061308	biolink:NamedThing	cardiac neural crest cell development involved in heart development	The process aimed at the progression of a cardiac neural crest cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell that contributes to the development of the heart.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-09-23T09:01:49Z					biological_process											owl:Class	
GO:0021597	biolink:NamedThing	central nervous system structural organization	The process that contributes to the act of creating the structural organization of the central nervous system structure. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain, spinal cord and spinal nerves. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord.	tmpzr1t_l9r_go_relaxed.owl	central nervous system structural organisation													biological_process											owl:Class	
GO:2000547	biolink:NamedThing	regulation of dendritic cell dendrite assembly	Any process that modulates the frequency, rate or extent of dendritic cell dendrite assembly.	tmpzr1t_l9r_go_relaxed.owl	regulation of dendritic extension							ebc	2011-04-03T07:21:55Z					biological_process											owl:Class	
GO:0097026	biolink:NamedThing	dendritic cell dendrite assembly	Formation of dendrites, branched cellular projections (or cytoplasmic extension) that are extended from the surface of a dendritic immune cell, and which enable the cell to sample luminal pathogens and increase the surface area for antigen presentation to T cells.	tmpzr1t_l9r_go_relaxed.owl	dendritic extension					Note that dendrites of dendritic cells should not be confused with neuronal cell dendrites, which process electrical signals.		pr	2011-03-31T04:52:53Z					biological_process											owl:Class	
GO:0075311	biolink:NamedThing	positive regulation of sporangium development	Any process that activates, maintains or increases the frequency, rate or extent of sporangium development, a process that leads to the formation of sporangium, a single-celled or many-celled structure in which spores are produced, as in fungi, algae, mosses, and ferns, gymnosperms, angiosperms.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0043708	biolink:NamedThing	cell adhesion involved in biofilm formation	The attachment of a cell to a solid substrate, via cell adhesion molecules, contributing to the formation of a biofilm.	tmpzr1t_l9r_go_relaxed.owl	cell adhesion during biofilm formation													biological_process											owl:Class	
GO:0060653	biolink:NamedThing	epithelial cell differentiation involved in mammary gland cord morphogenesis	The process in which a relatively unspecialized epithelial cell becomes a more specialized epithelial cell of the mammary gland cord. Epithelial cells of the mammary cord give it its funnel-like shape and some are cornified.	tmpzr1t_l9r_go_relaxed.owl	epithelial cell differentiation involved in mammary gland sprout morphogenesis							dph	2009-05-29T09:17:16Z					biological_process											owl:Class	
GO:0060652	biolink:NamedThing	mammary gland cord morphogenesis	The process in which anatomical structures of the mammary gland cord are generated and organized. Mammary gland cords form when the mammary gland bud invades the mammary fat.	tmpzr1t_l9r_go_relaxed.owl	mammary gland sprout morphogenesis							dph	2009-05-29T09:06:56Z					biological_process											owl:Class	
GO:0097361	biolink:NamedThing	CIA complex	The cytosolic iron-sulfur protein assembly (CIA) complex mediates the incorporation of iron-sulfur clusters into apoproteins involved in DNA metabolism and genomic integrity.	tmpzr1t_l9r_go_relaxed.owl	cytosolic iron-sulfur protein assembly complex							pr	2012-07-20T02:07:22Z					cellular_component											owl:Class	
GO:0070747	biolink:NamedThing	interleukin-35 receptor activity	Combining with interleukin-35 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	IL-35 receptor activity|IL-35R							mah	2009-06-23T01:18:09Z					molecular_function											owl:Class	
GO:0070746	biolink:NamedThing	interleukin-35 binding	Binding to interleukin-35.	tmpzr1t_l9r_go_relaxed.owl	IL-35 binding							mah	2009-06-23T01:15:36Z					molecular_function											owl:Class	
GO:0048449	biolink:NamedThing	floral organ formation	The process that gives rise to floral organs. This process pertains to the initial formation of a structure from unspecified parts.	tmpzr1t_l9r_go_relaxed.owl												GO:0048436		biological_process											owl:Class	
GO:0120263	biolink:NamedThing	positive regulation of heterochromatin organization	Any process that activates or increases the frequency, rate or extent of heterochromatin organization.	tmpzr1t_l9r_go_relaxed.owl	upregulation of heterochromatin organization|activation of heterochromatin organization|stimulation of heterochromatin organization|up regulation of heterochromatin organization|up-regulation of heterochromatin organization	https://github.com/geneontology/go-ontology/issues/20020						krc	2020-09-29T20:19:19Z					biological_process											owl:Class	
GO:0070828	biolink:NamedThing	heterochromatin organization	Any process that results in the specification, formation or maintenance of the physical structure of eukaryotic heterochromatin, a compact and highly condensed form of chromatin.	tmpzr1t_l9r_go_relaxed.owl	heterochromatin organisation							mah	2009-07-23T04:12:48Z					biological_process											owl:Class	
GO:0015213	biolink:NamedThing	uridine transmembrane transporter activity	Enables the transfer of uridine, uracil riboside, from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	uracil/uridine permease activity													molecular_function											owl:Class	
GO:0015862	biolink:NamedThing	uridine transport	The directed movement of uridine, uracil riboside, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0072001	biolink:NamedThing	renal system development	The process whose specific outcome is the progression of the renal system over time, from its formation to the mature structure. The renal system maintains fluid balance and contributes to electrolyte balance, acid/base balance, and disposal of nitrogenous waste products. In humans, the renal system comprises a pair of kidneys, a pair of ureters, urinary bladder, urethra, sphincter muscle and associated blood vessels.	tmpzr1t_l9r_go_relaxed.owl	urinary system development|urinary tract development							mah	2010-01-25T10:31:00Z					biological_process											owl:Class	
GO:0044611	biolink:NamedThing	nuclear pore inner ring	A subcomplex of the nuclear pore complex (NPC) that forms the inner rings of the core scaffold, a lattice-like structure that gives the NPC its shape and strength. In S. cerevisiae, the two inner rings are each composed of Nup192p, Nup188p, Nup170p and Nup157p. In vertebrates, the two inner rings are each composed of Nup205, Nup188 and Nup155. Components are arranged in 8-fold symmetrical 'spokes' around the central transport channel. A single 'spoke', can be isolated and is sometimes referred to as the Nup170 complex.	tmpzr1t_l9r_go_relaxed.owl	Nup170 complex							jl	2012-06-20T01:14:17Z					cellular_component											owl:Class	
GO:0106175	biolink:NamedThing	phagolysosome vesicle membrane	The lipid bylayer surrounding a phagolysosome.	tmpzr1t_l9r_go_relaxed.owl								hjd	2019-02-11T19:12:53Z					cellular_component											owl:Class	
GO:0032010	biolink:NamedThing	phagolysosome	A membrane-bounded intracellular vesicle formed by maturation of an early phagosome following the ingestion of particulate material by phagocytosis; during maturation, phagosomes acquire markers of late endosomes and lysosomes.	tmpzr1t_l9r_go_relaxed.owl	late phagosome|late phagocytic vesicle				Wikipedia:Phagolysosome									cellular_component											owl:Class	
GO:0035989	biolink:NamedThing	tendon development	The process whose specific outcome is the progression of a tendon over time, from its formation to the mature structure. A tendon is a fibrous, strong, connective tissue that connects muscle to bone or integument and is capable of withstanding tension. Tendons and muscles work together to exert a pulling force.	tmpzr1t_l9r_go_relaxed.owl	sinew development							bf	2011-08-26T04:14:30Z					biological_process											owl:Class	
GO:1900195	biolink:NamedThing	positive regulation of oocyte maturation	Any process that activates or increases the frequency, rate or extent of oocyte maturation.	tmpzr1t_l9r_go_relaxed.owl	up regulation of oocyte maturation|up-regulation of oocyte maturation|upregulation of oocyte maturation|activation of oocyte maturation							kmv	2012-03-19T09:41:35Z					biological_process											owl:Class	
GO:0007638	biolink:NamedThing	mechanosensory behavior	Behavior that is dependent upon the sensation of a mechanical stimulus.	tmpzr1t_l9r_go_relaxed.owl	behavioral response to mechanical stimulus|mechanosensory behaviour|behavioural response to mechanical stimulus													biological_process											owl:Class	
GO:0009612	biolink:NamedThing	response to mechanical stimulus	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mechanical stimulus.	tmpzr1t_l9r_go_relaxed.owl	chemi-mechanical coupling|mechanical stimulus response													biological_process											owl:Class	
GO:0060042	biolink:NamedThing	retina morphogenesis in camera-type eye	The process in which the anatomical structure of the retina is generated and organized.	tmpzr1t_l9r_go_relaxed.owl	retinogenesis|retina morphogenesis in camera-style eye													biological_process											owl:Class	
GO:0016593	biolink:NamedThing	Cdc73/Paf1 complex	A multiprotein complex that associates with RNA polymerase II and general RNA polymerase II transcription factor complexes and may be involved in both transcriptional initiation and elongation. In Saccharomyces the complex contains Paf1p, Cdc73p, Ctr9p, Rtf1p, and Leo1p.	tmpzr1t_l9r_go_relaxed.owl	Paf1 complex|Paf1p complex													cellular_component											owl:Class	
GO:1900497	biolink:NamedThing	regulation of butyryl-CoA catabolic process to butanol	Any process that modulates the frequency, rate or extent of butyryl-CoA catabolic process to butanol.	tmpzr1t_l9r_go_relaxed.owl	regulation of butyryl-CoA catabolism to butanol							tt	2012-05-02T03:53:20Z					biological_process											owl:Class	
GO:0044582	biolink:NamedThing	butyryl-CoA catabolic process to butanol	The chemical reactions a resulting in the resulting in the breakdown of butyryl-CoA to form butanol.	tmpzr1t_l9r_go_relaxed.owl	butyryl-CoA catabolism to butanol							jl	2012-04-19T04:40:06Z					biological_process											owl:Class	
GO:0006933	biolink:NamedThing	negative regulation of cell adhesion involved in substrate-bound cell migration	The disassembly of adhesions at the front and rear of a migrating cell. At the leading edge, adhesion disassembly accompanies the formation of new protrusions; at the cell rear, it promotes tail retraction.	tmpzr1t_l9r_go_relaxed.owl	substrate-bound cell migration, cell release from substrate													biological_process											owl:Class	
GO:0003211	biolink:NamedThing	cardiac ventricle formation	The developmental process pertaining to the initial formation of a cardiac ventricle from unspecified parts. A cardiac ventricle receives blood from a cardiac atrium and pumps it out of the heart.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-10-13T09:46:27Z					biological_process											owl:Class	
GO:0007502	biolink:NamedThing	digestive tract mesoderm development	The process whose specific outcome is the progression of the digestive tract mesoderm over time, from its formation to the mature structure. The digestive tract mesoderm is portion of the middle layer of the three primary germ layers of the embryo which will go on to form part of the digestive tract of the organism.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0072136	biolink:NamedThing	metanephric mesenchymal cell proliferation involved in metanephros development	The multiplication or reproduction of cells, resulting in the expansion of a metanephric mesenchymal cell population.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-02-22T02:34:56Z					biological_process											owl:Class	
GO:0072075	biolink:NamedThing	metanephric mesenchyme development	The biological process whose specific outcome is the progression of a metanephric mesenchyme from an initial condition to its mature state. This process begins with the formation of metanephric mesenchyme and ends with the mature structure. Metanephric mesenchyme is the tissue made up of loosely connected mesenchymal cells in the metanephros.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-01-25T04:40:11Z					biological_process											owl:Class	
GO:2001036	biolink:NamedThing	negative regulation of tongue muscle cell differentiation	Any process that stops, prevents or reduces the frequency, rate or extent of tongue muscle cell differentiation.	tmpzr1t_l9r_go_relaxed.owl								yaf	2011-08-24T11:10:20Z					biological_process											owl:Class	
GO:0035981	biolink:NamedThing	tongue muscle cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a tongue muscle cell.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-08-22T01:35:16Z					biological_process											owl:Class	
GO:0019218	biolink:NamedThing	regulation of steroid metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving steroids.	tmpzr1t_l9r_go_relaxed.owl	regulation of steroid metabolism													biological_process											owl:Class	
GO:0021793	biolink:NamedThing	chemorepulsion of branchiomotor axon	The process in which a branchiomotor neuron growth cone is directed to a specific target site in response to a repulsive chemical cue. Branchiomotor neurons are located in the hindbrain and innervate branchial arch-derived muscles that control jaw movements, facial expression, the larynx, and the pharynx.	tmpzr1t_l9r_go_relaxed.owl	negative chemotaxis of branchiomotor axon													biological_process											owl:Class	
GO:0021785	biolink:NamedThing	branchiomotor neuron axon guidance	The process in which a branchiomotor neuron growth cone is directed to a specific target site. Branchiomotor neurons are located in the hindbrain and innervate branchial arch-derived muscles that control jaw movements, facial expression, the larynx, and the pharynx.	tmpzr1t_l9r_go_relaxed.owl	BMN axon guidance|branchial motor axon guidance|special visceral motor neuron axon guidance													biological_process											owl:Class	
GO:0033018	biolink:NamedThing	sarcoplasmic reticulum lumen	The volume enclosed by the membranes of the sarcoplasmic reticulum.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0072189	biolink:NamedThing	ureter development	The process whose specific outcome is the progression of the ureter over time, from its formation to the mature structure. The ureter is a muscular tube that transports urine from the kidney to the urinary bladder or from the Malpighian tubule to the hindgut.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-03-01T01:44:14Z					biological_process											owl:Class	
GO:0002899	biolink:NamedThing	negative regulation of central B cell deletion	Any process that stops, prevents, or reduces the frequency, rate, or extent of central B cell deletion.	tmpzr1t_l9r_go_relaxed.owl	down regulation of central B cell deletion|down-regulation of central B cell deletion|downregulation of central B cell deletion|inhibition of central B cell deletion													biological_process											owl:Class	
GO:0002342	biolink:NamedThing	central B cell deletion	The deletion of B cells by apoptotic process occurring as part of central tolerance induction and B cell selection.	tmpzr1t_l9r_go_relaxed.owl	central B lymphocyte deletion|central B-lymphocyte deletion|central B-cell deletion													biological_process											owl:Class	
GO:0001658	biolink:NamedThing	branching involved in ureteric bud morphogenesis	The process in which the branching structure of the ureteric bud is generated and organized. The ureteric bud is an epithelial tube that grows out from the metanephric duct. The bud elongates and branches to give rise to the ureter and kidney collecting tubules.	tmpzr1t_l9r_go_relaxed.owl	ureteric bud branching													biological_process											owl:Class	
GO:0005621	biolink:NamedThing	cellular bud scar	Crater-like ring of chitinous scar tissue located on the surface of the mother cell. It is formed after the newly emerged daughter cell separates thereby marking the site of cytokinesis and septation. The number of bud scars that accumulate on the surface of a cell is a useful determinant of replicative age.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:1902407	biolink:NamedThing	assembly of actomyosin apparatus involved in mitotic cytokinesis	Any assembly of mitotic cytokinetic actomyosin apparatus.	tmpzr1t_l9r_go_relaxed.owl	cytokinesis, formation of actomyosin apparatus involved in mitotic cell cycle|formation of actomyosin apparatus involved in cytokinesis involved in mitotic cell cycle|actomyosin apparatus assembly involved in cytokinesis involved in mitotic cell cycle							jl	2013-09-12T12:28:22Z					biological_process											owl:Class	
GO:0043676	biolink:NamedThing	tectum	The layer of sexine which forms a roof over the columella, granules or other infratectal elements.	tmpzr1t_l9r_go_relaxed.owl	sexine 2													cellular_component											owl:Class	
GO:0043673	biolink:NamedThing	sexine	The outer, sculptured layer of the exine, which lies above the nexine.	tmpzr1t_l9r_go_relaxed.owl						Note that the sexine sometimes consists of 5 layers, but of those, 3 layers are the most common (sexine 1 = columellae; sexine 2 = tectum; sexine 3 = sculpture elements). Sexine is distinguished on purely morphological criteria; compare with 'ectexine ; GO:0043669'. See also 'nexine ; GO:0043672'.								cellular_component											owl:Class	
GO:2000864	biolink:NamedThing	regulation of estradiol secretion	Any process that modulates the frequency, rate or extent of estradiol secretion.	tmpzr1t_l9r_go_relaxed.owl	regulation of oestradiol secretion							bf	2011-07-26T08:49:13Z					biological_process											owl:Class	
GO:0035938	biolink:NamedThing	estradiol secretion	The regulated release of estradiol into the circulatory system.	tmpzr1t_l9r_go_relaxed.owl	oestradiol secretion							bf	2011-07-20T01:16:45Z					biological_process											owl:Class	
GO:0098894	biolink:NamedThing	extrinsic component of presynaptic endocytic zone membrane	The component of the presynaptic endocytic zone membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0071554	biolink:NamedThing	cell wall organization or biogenesis	A process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a cell wall.	tmpzr1t_l9r_go_relaxed.owl	cell wall organization or biogenesis at cellular level|cell wall organisation or biogenesis|cellular cell wall organization or biogenesis|cellular cell wall organisation or biogenesis							mah	2010-01-13T03:19:38Z			GO:0070882		biological_process											owl:Class	
GO:1903461	biolink:NamedThing	Okazaki fragment processing involved in mitotic DNA replication	Any DNA replication, Okazaki fragment processing that is involved in mitotic cell cycle DNA replication.	tmpzr1t_l9r_go_relaxed.owl	DNA replication, Okazaki fragment processing involved in DNA replication involved in S phase involved in mitotic cell cycle|DNA replication, Okazaki fragment processing involved in mitotic nuclear cell cycle DNA replication|DNA replication, Okazaki fragment processing involved in DNA replication during S phase involved in mitotic cell cycle|DNA replication, Okazaki fragment processing involved in nuclear cell cycle DNA replication involved in mitotic cell cycle|DNA replication, Okazaki fragment processing involved in DNA replication involved in S-phase involved in mitotic cell cycle							vw	2014-09-23T13:33:11Z					biological_process											owl:Class	
GO:0072185	biolink:NamedThing	metanephric cap development	The biological process whose specific outcome is the progression of the metanephric cap from an initial condition to its mature state. The metanephric cap is formed by the condensation of metanephric mesenchymal cells surrounding the ureteric bud tip.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-03-01T01:20:22Z					biological_process											owl:Class	
GO:1905082	biolink:NamedThing	regulation of mitochondrial translational elongation	Any process that modulates the frequency, rate or extent of mitochondrial translational elongation.	tmpzr1t_l9r_go_relaxed.owl	regulation of mitochondrial translation elongation							hjd	2016-03-25T17:37:03Z					biological_process											owl:Class	
GO:0070527	biolink:NamedThing	platelet aggregation	The adhesion of one platelet to one or more other platelets via adhesion molecules.	tmpzr1t_l9r_go_relaxed.owl	blood platelet aggregation|thrombocyte aggregation													biological_process											owl:Class	
GO:0001654	biolink:NamedThing	eye development	The process whose specific outcome is the progression of the eye over time, from its formation to the mature structure. The eye is the organ of sight.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Eye_development							GO:0042460		biological_process											owl:Class	
GO:1903355	biolink:NamedThing	negative regulation of distal tip cell migration	Any process that stops, prevents or reduces the frequency, rate or extent of distal tip cell migration.	tmpzr1t_l9r_go_relaxed.owl	downregulation of distal tip cell migration|inhibition of distal tip cell migration|down regulation of distal tip cell migration|down-regulation of distal tip cell migration							pr	2014-08-21T10:05:17Z					biological_process											owl:Class	
GO:0060236	biolink:NamedThing	regulation of mitotic spindle organization	Any process that modulates the rate, frequency or extent of the assembly, arrangement of constituent parts, or disassembly of the microtubule spindle during a mitotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl	regulation of mitotic spindle organization and biogenesis|regulation of mitotic spindle organisation													biological_process											owl:Class	
GO:1904091	biolink:NamedThing	peptidyl carrier protein activity	Binding an amino-acid derived peptidyl group and presenting it for processing or offloading to a cognate enzyme. Covalently binds the peptidyl group via a phosphopantetheine prosthetic group and mediates protein-protein interactions with the enzyme conferring specificity. Peptidyl carrier protein (PCP) is involved in nonribosomal peptide biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	Oligopeptid binding involved in nonribosomal peptide biosynthetic process|oligopeptides binding involved in nonribosomal peptide biosynthetic process|oligopeptides binding involved in non-ribosomal peptide formation|oligopeptide binding involved in non-ribosomal peptide biosynthetic process|Oligopeptid binding involved in nonribosomal peptide synthetase|oligopeptido binding involved in nonribosomal peptide biosynthetic process|oligopeptides binding involved in nonribosomal peptide anabolism|oligopeptido binding involved in nonribosomal peptide synthetase|peptidyl binding involved in nonribosomal peptide biosynthetic process|Oligopeptid binding involved in non-ribosomal peptide biosynthesis|peptidyl binding involved in nonribosomal peptide biosynthesis|oligopeptide binding involved in nonribosomal peptide biosynthesis|oligopeptido binding involved in non-ribosomal peptide biosynthetic process|oligopeptides binding involved in nonribosomal peptide synthetase|oligopeptides binding involved in nonribosomal peptide synthesis|oligopeptide binding involved in nonribosomal peptide formation|oligopeptide binding involved in nonribosomal peptide biosynthetic process|oligopeptides binding involved in nonribosomal peptide biosynthesis|Oligopeptid binding involved in nonribosomal peptide anabolism|oligopeptido binding involved in non-ribosomal peptide formation|oligopeptido binding involved in nonribosomal peptide anabolism|oligopeptides binding involved in non-ribosomal peptide biosynthetic process|Oligopeptid binding involved in non-ribosomal peptide biosynthetic process|peptidyl carrier protein|Oligopeptid binding involved in nonribosomal peptide biosynthesis|oligopeptido binding involved in nonribosomal peptide formation|oligopeptides binding involved in non-ribosomal peptide synthesis|Oligopeptid binding involved in non-ribosomal peptide synthesis|peptidyl carrier protein activity involved in nonribosomal peptide biosynthesis|oligopeptide binding involved in non-ribosomal peptide synthesis|oligopeptide binding involved in nonribosomal peptide anabolism|peptidyl carrier protein activity involved in nonribosomal peptide biosynthetic process|oligopeptido binding involved in non-ribosomal peptide biosynthesis|Oligopeptid binding involved in nonribosomal peptide synthesis|oligopeptide binding involved in nonribosomal peptide synthetase|oligopeptides binding involved in non-ribosomal peptide biosynthesis|Oligopeptid binding involved in nonribosomal peptide formation|oligopeptide binding involved in non-ribosomal peptide formation|oligopeptides binding involved in nonribosomal peptide formation|Oligopeptid binding involved in non-ribosomal peptide formation|oligopeptido binding involved in nonribosomal peptide biosynthesis|oligopeptide binding involved in non-ribosomal peptide biosynthesis|oligopeptido binding involved in nonribosomal peptide synthesis|oligopeptide binding involved in nonribosomal peptide synthesis|PCP|oligopeptido binding involved in non-ribosomal peptide synthesis					Examples are the ferrichrome synthetase Sib1 in S. pombe and the peptidyl carrier protein (PCP) module in bacterial nonribosomal peptide synthases (NRPSs), which holds the peptidyl group and acts as a swinging arm, limiting diffusion until the peptide comes into contact with the next enzymatic module in the NRPS process.		pr	2015-03-26T10:41:52Z					molecular_function											owl:Class	
GO:0019184	biolink:NamedThing	nonribosomal peptide biosynthetic process	The biosynthetic process in which peptide bond formation occurs in the absence of the translational machinery. Examples include the synthesis of antibiotic peptides, and glutathione.	tmpzr1t_l9r_go_relaxed.owl	nonribosomal peptide formation|nonribosomal peptide synthesis|nonribosomal peptide synthetase|non-ribosomal peptide biosynthetic process|non-ribosomal peptide formation|nonribosomal peptide anabolism|non-ribosomal peptide biosynthesis|non-ribosomal peptide synthesis|nonribosomal peptide biosynthesis													biological_process											owl:Class	
GO:0021610	biolink:NamedThing	facial nerve morphogenesis	The process in which the anatomical structure of the facial nerve is generated and organized. This sensory and motor nerve supplies the muscles of facial expression and the expression and taste at the anterior two-thirds of the tongue. The principal branches are the superficial opthalmic, buccal, palatine and hyomandibular. The main trunk synapses within pterygopalatine ganglion in the parotid gland and this ganglion then gives of nerve branches which supply the lacrimal gland and the mucous secreting glands of the nasal and oral cavities.	tmpzr1t_l9r_go_relaxed.owl	CN VII morphogenesis													biological_process											owl:Class	
GO:0021561	biolink:NamedThing	facial nerve development	The process whose specific outcome is the progression of the facial nerve over time, from its formation to the mature structure. This sensory and motor nerve supplies the muscles of facial expression and the expression and taste at the anterior two-thirds of the tongue. The principal branches are the superficial opthalmic, buccal, palatine and hyomandibular. The main trunk synapses within pterygopalatine ganglion in the parotid gland and this ganglion then gives off nerve branches which supply the lacrimal gland and the mucous secreting glands of the nasal and oral cavities.	tmpzr1t_l9r_go_relaxed.owl	CN VII development|cranial nerve 7 development|cranial nerve VII development													biological_process											owl:Class	
GO:0044777	biolink:NamedThing	single-stranded DNA-binding protein complex	A homotetrameric protein complex that is essential for DNA replication. It supercoils the single-stranded DNA preventing DNA duplexing before the polymerase holoenzyme passes and synthesizes the complementary strand. It is also involved in DNA recombination and repair.	tmpzr1t_l9r_go_relaxed.owl	SSB complex							jl	2013-03-14T13:14:00Z					cellular_component											owl:Class	
GO:0002023	biolink:NamedThing	reduction of food intake in response to dietary excess	An eating behavior process whereby detection of a dietary excess results in a decrease in intake of nutrients.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0035772	biolink:NamedThing	interleukin-13-mediated signaling pathway	A series of molecular signals initiated by the binding of interleukin-13 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.	tmpzr1t_l9r_go_relaxed.owl	IL-13-mediated signaling pathway|interleukin-13-mediated signalling pathway							bf	2011-04-01T11:00:11Z					biological_process											owl:Class	
GO:0035963	biolink:NamedThing	cellular response to interleukin-13	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-13 stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to IL-13							bf	2011-08-01T11:29:42Z					biological_process											owl:Class	
GO:0045471	biolink:NamedThing	response to ethanol	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ethanol stimulus.	tmpzr1t_l9r_go_relaxed.owl												GO:0017036		biological_process											owl:Class	
GO:0099109	biolink:NamedThing	potassium channel activating, G protein-coupled receptor signaling pathway	The series of molecular signals generated as a consequence of a G protein-coupled receptor binding to its physiological ligand, where the pathway proceeds activation of a potassium ion channel.	tmpzr1t_l9r_go_relaxed.owl	potassium channel activating, G-protein coupled receptor signaling pathway													biological_process											owl:Class	
GO:0001164	biolink:NamedThing	RNA polymerase I core promoter sequence-specific DNA binding	Binding to a regulatory region composed of the transcription start site and binding sites for transcription factors of the RNA polymerase I transcription machinery. This site is often referred to as the CORE element. In mammalian cells, the CORE element functions in conjunction with the Upstream Control Element (UCE), while in fungi, protozoa, and plants, the CORE element functions without a UCE.	tmpzr1t_l9r_go_relaxed.owl	RNA polymerase I CORE element sequence-specific DNA binding|RNA polymerase I CORE element sequence-specific DNA binding transcription factor recruiting transcription factor activity|transcription factor activity, RNA polymerase I CORE element binding transcription factor recruiting							krc	2011-01-31T04:47:48Z			GO:0001187		molecular_function											owl:Class	
GO:0001188	biolink:NamedThing	RNA polymerase I preinitiation complex assembly	The aggregation, arrangement and bonding together of proteins on promoter DNA to form the transcriptional preinitiation complex (PIC), the formation of which is a prerequisite for transcription from an RNA polymerase I promoter.	tmpzr1t_l9r_go_relaxed.owl	RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nucleolar primary rRNA transcript|RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript|RNA polymerase I transcriptional preinitiation complex assembly							krc	2011-08-24T04:16:28Z			GO:0001189		biological_process											owl:Class	
GO:0070424	biolink:NamedThing	regulation of nucleotide-binding oligomerization domain containing signaling pathway	Any process that modulates the frequency, rate, or extent of a nucleotide-binding oligomerization domain containing (NOD) pathway.	tmpzr1t_l9r_go_relaxed.owl	regulation of NOD signaling pathway|regulation of nucleotide-binding oligomerization domain containing signalling pathway													biological_process											owl:Class	
GO:0070423	biolink:NamedThing	nucleotide-binding oligomerization domain containing signaling pathway	Any series of molecular signals generated as a consequence of binding to a nucleotide-binding oligomerization domain containing (NOD) protein.	tmpzr1t_l9r_go_relaxed.owl	NOD signaling pathway|nucleotide-binding oligomerization domain containing signalling pathway													biological_process											owl:Class	
GO:0060448	biolink:NamedThing	dichotomous subdivision of terminal units involved in lung branching	The process in which a lung bud bifurcates.	tmpzr1t_l9r_go_relaxed.owl	bud bifurcation involved in lung branching													biological_process											owl:Class	
GO:0060441	biolink:NamedThing	epithelial tube branching involved in lung morphogenesis	The process in which a highly ordered sequence of patterning events generates the branched epithelial tubes of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units.	tmpzr1t_l9r_go_relaxed.owl	lung branching morphogenesis													biological_process											owl:Class	
GO:0060765	biolink:NamedThing	regulation of androgen receptor signaling pathway	Any process that modulates the rate, frequency, or extent of the androgen receptor signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	regulation of androgen receptor signalling pathway							dph	2009-07-06T11:07:38Z					biological_process											owl:Class	
GO:0030521	biolink:NamedThing	androgen receptor signaling pathway	Any series of molecular signals generated as a consequence of an androgen binding to its receptor.	tmpzr1t_l9r_go_relaxed.owl	androgen receptor signalling pathway													biological_process											owl:Class	
GO:0007342	biolink:NamedThing	fusion of sperm to egg plasma membrane involved in single fertilization	The binding and fusion of a sperm, with the plasma membrane of the oocyte as part of the process of single fertilization. In sperm with flagella, binding occurs at the posterior (post-acrosomal) region of the sperm head.	tmpzr1t_l9r_go_relaxed.owl	sperm-oocyte fusion													biological_process											owl:Class	
GO:0072560	biolink:NamedThing	type B pancreatic cell maturation	A developmental process, independent of morphogenetic (shape) change, that is required for a type B pancreatic cell to attain its fully functional state. A type B pancreatic cell is a cell located towards center of the islets of Langerhans that secretes insulin.	tmpzr1t_l9r_go_relaxed.owl	pancreatic B cell maturation|pancreatic beta cell maturation					These processes continue to 60 DPA in Gossypium spp.		mah	2011-01-27T01:57:14Z					biological_process											owl:Class	
GO:0009654	biolink:NamedThing	photosystem II oxygen evolving complex	A complex, composed of a cluster of manganese, calcium and chloride ions bound to extrinsic proteins, that catalyzes the splitting of water to O2 and 4 H+. In cyanobacteria there are five extrinsic proteins in OEC (PsbO, PsbP-like, PsbQ-like, PsbU and PsbV), while in plants there are only three (PsbO, PsbP and PsbQ).	tmpzr1t_l9r_go_relaxed.owl	oxygen evolving complex|OEC (PSII) complex				Wikipedia:Oxygen_evolving_complex									cellular_component											owl:Class	
GO:0009523	biolink:NamedThing	photosystem II	A photosystem that contains a pheophytin-quinone reaction center with associated accessory pigments and electron carriers. In cyanobacteria and chloroplasts, in the presence of light, PSII functions as a water-plastoquinone oxidoreductase, transferring electrons from water to plastoquinone, whereas other photosynthetic bacteria carry out anoxygenic photosynthesis and oxidize other compounds to re-reduce the photoreaction center.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Photosystem_II									cellular_component											owl:Class	
GO:0061458	biolink:NamedThing	reproductive system development	The progression of the reproductive system over time from its formation to the mature structure. The reproductive system consists of the organs that function in reproduction.	tmpzr1t_l9r_go_relaxed.owl								dph	2012-08-22T17:47:53Z					biological_process											owl:Class	
GO:1900159	biolink:NamedThing	positive regulation of bone mineralization involved in bone maturation	Any process that activates or increases the frequency, rate or extent of bone mineralization involved in bone maturation.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of bone mineralization involved in bone maturation|up regulation of bone mineralization involved in bone maturation|activation of bone mineralization involved in bone maturation|upregulation of bone mineralization involved in bone maturation							vk	2012-03-07T08:55:16Z					biological_process											owl:Class	
GO:0035630	biolink:NamedThing	bone mineralization involved in bone maturation	The deposition of hydroxyapatite, involved in the progression of the skeleton from its formation to its mature state.	tmpzr1t_l9r_go_relaxed.owl						Bone mineralization can also occur after a fracture and as a response to stress; in these cases, consider using the term 'bone mineralization ; GO:0030282'.		bf	2010-12-20T01:57:31Z					biological_process											owl:Class	
GO:0010324	biolink:NamedThing	membrane invagination	The infolding of a membrane.	tmpzr1t_l9r_go_relaxed.owl	single-organism membrane invagination							jl	2013-12-02T13:58:34Z			GO:1902534		biological_process											owl:Class	
GO:0043996	biolink:NamedThing	histone acetyltransferase activity (H4-K8 specific)	Catalysis of the reaction: acetyl-CoA + histone H4 L-lysine (position 8) = CoA + histone H4 N6-acetyl-L-lysine (position 8).	tmpzr1t_l9r_go_relaxed.owl	histone lysine N-acetyltransferase activity (H4-K8 specific)													molecular_function											owl:Class	
GO:0043982	biolink:NamedThing	histone H4-K8 acetylation	The modification of histone H4 by the addition of an acetyl group to a lysine residue at position 8 of the histone.	tmpzr1t_l9r_go_relaxed.owl	histone H4 acetylation at K8													biological_process											owl:Class	
GO:0070810	biolink:NamedThing	positive regulation of Hulle cell development	Any process that activates or increases the frequency, rate or extent of Hulle cell development, a process that leads to the formation of Hulle cells. Hulle cells are specialized multinucleate cells that originate from a nest-like aggregation of hyphae during sexual development and serve as nurse cells to the developing cleistothecium, or fruiting body.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-07-08T04:54:12Z					biological_process											owl:Class	
GO:0070792	biolink:NamedThing	Hulle cell development	The process whose specific outcome is the progression of Hulle cells over time, from their formation to the mature structures. Hulle cells are specialized multinucleate cells that originate from a nest-like aggregation of hyphae during sexual development and serve as nurse cells to the developing cleistothecium, or fruiting body.	tmpzr1t_l9r_go_relaxed.owl	Huelle cell development|Hulle cell formation							mah	2009-07-08T02:54:30Z					biological_process											owl:Class	
GO:0051306	biolink:NamedThing	mitotic sister chromatid separation	The process in which sister chromatids are physically detached from each other during mitosis.	tmpzr1t_l9r_go_relaxed.owl	mitotic sister chromatid resolution|sister chromatid separation during mitosis|mitotic chromosome separation|chromosome separation during mitosis													biological_process											owl:Class	
GO:0003968	biolink:NamedThing	RNA-directed 5'-3' RNA polymerase activity	Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1); uses an RNA template, i.e. the catalysis of RNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.	tmpzr1t_l9r_go_relaxed.owl	ribonucleic acid-dependent ribonucleate nucleotidyltransferase activity|RNA-dependent RNA polymerase activity|RNA-dependent RNA replicase activity|ribonucleic acid-dependent ribonucleic acid polymerase activity|polymerase L|RNA-directed RNA polymerase activity|RNA replicase activity|ribonucleic acid replicase activity|PB1 proteins|transcriptase|RNA synthetase activity|phage f2 replicase|RNA-dependent ribonucleate nucleotidyltransferase activity|nucleoside-triphosphate:RNA nucleotidyltransferase (RNA-directed)|Q-beta replicase activity|RDRP|ribonucleic replicase activity|PB2 proteins|RNA nucleotidyltransferase (RNA-directed) activity|3D polymerase activity|ribonucleic synthetase activity				Reactome:R-HSA-9694605|Reactome:R-HSA-192916|Reactome:R-HSA-9685639|Reactome:R-HSA-9685681|Reactome:R-HSA-9694549|Reactome:R-HSA-9682563|EC:2.7.7.48|Reactome:R-HSA-168301|Reactome:R-HSA-192851|Reactome:R-HSA-9694506|Reactome:R-HSA-192624|Reactome:R-HSA-9694277|Reactome:R-HSA-9681674|Reactome:R-HSA-168280|Reactome:R-HSA-9694581|Reactome:R-HSA-9682465|Reactome:R-HSA-9694792|MetaCyc:RNA-DIRECTED-RNA-POLYMERASE-RXN|Reactome:R-HSA-9681840|Reactome:R-HSA-9694344|Reactome:R-HSA-9681651|Reactome:R-HSA-192832									molecular_function											owl:Class	
GO:0060287	biolink:NamedThing	epithelial cilium movement involved in determination of left/right asymmetry	The movement of cilia of epithelial cells of the Left Right Organizer (LRO), also referred to as the node in mouse or the Kupffer's vesicle in zebrafish, resulting in the leftward fluid flow across the LRO and generation or transport of a signal which determines asymmetry in an organism's body plan with respect to the left and right halves.	tmpzr1t_l9r_go_relaxed.owl	nodal cilium movement involved in determination of left/right asymmetry|cilium movement involved in determinationof L/R asymmetry|Kuppfer's vesicle cilium movement involved in determination of left/right asymmetry													biological_process											owl:Class	
GO:0007368	biolink:NamedThing	determination of left/right symmetry	The establishment of an organism's body plan or part of an organism with respect to the left and right halves. The pattern can either be symmetric, such that the halves are mirror images, or asymmetric where the pattern deviates from this symmetry.	tmpzr1t_l9r_go_relaxed.owl	determination of left/right asymmetry													biological_process											owl:Class	
GO:0086041	biolink:NamedThing	voltage-gated potassium channel activity involved in SA node cell action potential depolarization	Enables the transmembrane transfer of a potassium ion by a voltage-gated channel through the plasma membrane of an SA node cardiac muscle cell contributing to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.	tmpzr1t_l9r_go_relaxed.owl	voltage-gated potassium channel activity involved in sinus node cell action potential depolarization|voltage-gated potassium channel activity involved in SAN cell action potential depolarization|voltage-gated potassium channel activity involved in sinoatrial node cell action potential depolarization							tb	2011-11-11T03:37:42Z					molecular_function											owl:Class	
GO:1903583	biolink:NamedThing	positive regulation of basophil degranulation	Any process that activates or increases the frequency, rate or extent of basophil degranulation.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of basophil degranulation|activation of basophil degranulation|upregulation of basophil degranulation|up regulation of basophil degranulation							sl	2014-10-31T17:37:42Z					biological_process											owl:Class	
GO:0060575	biolink:NamedThing	intestinal epithelial cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a columnar/cuboidal epithelial cell of the intestine.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-05-06T08:17:56Z					biological_process											owl:Class	
GO:0031561	biolink:NamedThing	cellular bud tip polarisome	Protein complex that has a role in determining cell polarity, found at the tip of a growing fungal bud.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0005934	biolink:NamedThing	cellular bud tip	The end of a cellular bud distal to the site of attachment to the mother cell.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:2000345	biolink:NamedThing	regulation of hepatocyte proliferation	Any process that modulates the frequency, rate or extent of hepatocyte proliferation.	tmpzr1t_l9r_go_relaxed.owl								mah	2011-02-03T10:27:15Z					biological_process											owl:Class	
GO:0072574	biolink:NamedThing	hepatocyte proliferation	The multiplication or reproduction of hepatocytes, resulting in the expansion of a cell population. Hepatocytes form the main structural component of the liver. They are specialized epithelial cells that are organized into interconnected plates called lobules.	tmpzr1t_l9r_go_relaxed.owl								mah	2011-02-02T03:34:49Z					biological_process											owl:Class	
GO:0001058	biolink:NamedThing	RNA polymerase V activity	Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template that contains an RNA polymerase V specific promoter to direct initiation and catalyses DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'.	tmpzr1t_l9r_go_relaxed.owl	DNA-directed RNA polymerase activity involved in transcription from RNA polymerase V promoter							krc	2010-09-23T03:45:01Z					molecular_function											owl:Class	
GO:0061008	biolink:NamedThing	hepaticobiliary system development	The progression of the hepaticobiliary system over time, from its formation to the mature structure. The hepaticobiliary system is responsible for metabolic and catabolic processing of small molecules absorbed from the blood or gut, hormones and serum proteins, detoxification, storage of glycogen, triglycerides, metals and lipid soluble vitamins and excretion of bile. Included are the synthesis of albumin, blood coagulation factors, complement, and specific binding proteins.	tmpzr1t_l9r_go_relaxed.owl	hepatobiliary system development							dph	2010-01-22T09:11:59Z					biological_process											owl:Class	
GO:0048599	biolink:NamedThing	oocyte development	The process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1903104	biolink:NamedThing	regulation of insulin receptor signaling pathway involved in determination of adult lifespan	Any process that modulates the frequency, rate or extent of insulin receptor signaling pathway involved in determination of adult lifespan.	tmpzr1t_l9r_go_relaxed.owl	regulation of insulin receptor signalling pathway of determination of adult lifespan|regulation of insulin receptor signaling pathway of determination of adult lifespan|regulation of daf-2 receptor signaling pathway of determination of adult lifespan							kmv	2014-06-05T20:56:06Z					biological_process											owl:Class	
GO:0140025	biolink:NamedThing	contractile vacuole tethering involved in discharge	The initial, indirect interaction between a contractile vacuole membrane and a site of discharge in the plasma membrane. This interaction is mediated by tethering factors (or complexes), which interact with both membranes. Interaction can occur via direct binding to membrane phospholipids or membrane proteins, or via binding to vesicle coat proteins. This process is distinct from and prior to docking and fusion.	tmpzr1t_l9r_go_relaxed.owl	contractile vacuole tethering to plasma membrane	https://github.com/geneontology/go-ontology/issues/13407						pg	2017-05-02T09:50:10Z					biological_process											owl:Class	
GO:0070177	biolink:NamedThing	contractile vacuole discharge	The regulated release of water from a contractile vacuole to the outside of a cell by fusion of the contractile vacuole membrane with the plasma membrane.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0060943	biolink:NamedThing	neural crest-derived cardiac fibroblast cell development	The process whose specific outcome is the progression of a cardiac fibroblast over time, from its formation from a neural crest cell to the mature state. A cardiac fibroblast is a connective tissue cell of the heart which secretes an extracellular matrix rich in collagen and other macromolecules.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-09-29T02:31:24Z					biological_process											owl:Class	
GO:0015979	biolink:NamedThing	photosynthesis	The synthesis by organisms of organic chemical compounds, especially carbohydrates, from carbon dioxide (CO2) using energy obtained from light rather than from the oxidation of chemical compounds.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Photosynthesis									biological_process											owl:Class	
GO:0008385	biolink:NamedThing	IkappaB kinase complex	A trimeric protein complex that phosphorylates inhibitory-kappaB (I-kappaB) proteins. The complex is composed of two kinase subunits (alpha and beta) and a regulatory gamma subunit (also called NEMO). In a resting state, NF-kappaB dimers are bound to inhibitory IKB proteins, sequestering NF-kappaB in the cytoplasm. Phosphorylation of I-kappaB targets I-kappaB for ubiquitination and proteasomal degradation, thus releasing the NF-kappaB dimers, which can translocate to the nucleus to bind DNA and regulate transcription.	tmpzr1t_l9r_go_relaxed.owl	trimeric IKK complex|IKK complex|heterotrimeric IKK complex													cellular_component											owl:Class	
GO:0007292	biolink:NamedThing	female gamete generation	Generation of the female gamete; specialised haploid cells produced by meiosis and along with a male gamete takes part in sexual reproduction.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0036462	biolink:NamedThing	TRAIL-activated apoptotic signaling pathway	An extrinsic apoptotic signaling pathway initiated by the binding of the ligand TRAIL (tumor necrosis factor-related apoptosis-inducing ligand) to a death receptor on the cell surface.	tmpzr1t_l9r_go_relaxed.owl	TRAIL-induced apoptotic signaling pathway|TRAIL-activated extrinsic apoptotic signaling pathway|tumor necrosis factor-related apoptosis-inducing ligand apoptotic signaling pathway							bf	2014-06-11T09:18:41Z					biological_process											owl:Class	
GO:0075036	biolink:NamedThing	regulation of appressorium maturation	Any process that modulates the frequency, rate or extent of symbiont appressorium maturation.	tmpzr1t_l9r_go_relaxed.owl	regulation of appressorium maturation on or near host|regulation of maturation of appressorium on or near host													biological_process											owl:Class	
GO:0090263	biolink:NamedThing	positive regulation of canonical Wnt signaling pathway	Any process that increases the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin, the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of catenin import into nucleus|positive regulation of canonical Wnt receptor signalling pathway|positive regulation of canonical Wnt receptor signaling pathway|positive regulation of catenin protein nuclear translocation|positive regulation of Wnt receptor signaling pathway through beta-catenin|positive regulation of canonical Wnt-activated signaling pathway							tb	2010-02-03T04:32:16Z			GO:0035413		biological_process											owl:Class	
GO:0035379	biolink:NamedThing	carbon dioxide transmembrane transporter activity	Enables the transfer of carbon dioxide (CO2) from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-1237069|Reactome:R-HSA-1247649|Reactome:R-HSA-1247645|Reactome:R-HSA-1237042			bf	2010-03-18T11:19:38Z					molecular_function											owl:Class	
GO:0035378	biolink:NamedThing	carbon dioxide transmembrane transport	The process in which carbon dioxide (CO2) is transported across a membrane.	tmpzr1t_l9r_go_relaxed.owl	carbon dioxide membrane transport					Note that this term is not intended for use in annotating lateral movement within membranes.		bf	2010-03-18T11:17:54Z					biological_process											owl:Class	
GO:0010102	biolink:NamedThing	lateral root morphogenesis	The process in which the anatomical structures of a lateral root are generated and organized. A lateral root is one formed from pericycle cells located on the xylem radius of the root, as opposed to the initiation of the main root from the embryo proper.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0048527	biolink:NamedThing	lateral root development	The process whose specific outcome is the progression of the lateral root over time, from its formation to the mature structure. A lateral root is one formed from pericycle cells located on the xylem radius of the root, as opposed to the initiation of the main root from the embryo proper.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0098557	biolink:NamedThing	cytoplasmic side of smooth endoplasmic reticulum membrane	The side (leaflet) of the smooth endoplasmic reticulum membrane that faces the cytoplasm.	tmpzr1t_l9r_go_relaxed.owl								dos	2013-12-03T12:17:58Z					cellular_component											owl:Class	
GO:0030868	biolink:NamedThing	smooth endoplasmic reticulum membrane	The lipid bilayer surrounding the smooth endoplasmic reticulum.	tmpzr1t_l9r_go_relaxed.owl	SER membrane|smooth ER membrane				NIF_Subcellular:sao1596955044									cellular_component											owl:Class	
GO:1905798	biolink:NamedThing	positive regulation of intraciliary anterograde transport	Any process that activates or increases the frequency, rate or extent of intraciliary anterograde transport.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of intraflagellar anterograde transport|upregulation of intraciliary anterograde transport|upregulation of intraflagellar anterograde transport|activation of intraciliary anterograde transport|up-regulation of intraciliary anterograde transport|positive regulation of intraflagellar anterograde transport|activation of intraflagellar anterograde transport|up regulation of intraciliary anterograde transport|up regulation of intraflagellar anterograde transport							hbye	2017-01-11T12:56:01Z					biological_process											owl:Class	
GO:0035720	biolink:NamedThing	intraciliary anterograde transport	The directed movement of large protein complexes along microtubules from the cell body toward the tip of a cilium (also called flagellum), mediated by motor proteins.	tmpzr1t_l9r_go_relaxed.owl	intraflagellar anterograde transport					Note that we deem cilium and microtubule-based flagellum to be equivalent.		bf	2011-03-07T11:24:53Z					biological_process											owl:Class	
GO:0021585	biolink:NamedThing	pons structural organization	The process that contributes to the act of creating the structural organization of the pons. This process pertains to the physical shaping of a rudimentary structure. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum.	tmpzr1t_l9r_go_relaxed.owl	pons structural organisation													biological_process											owl:Class	
GO:1901254	biolink:NamedThing	positive regulation of intracellular transport of viral material	Any process that activates or increases the frequency, rate or extent of intracellular transport of viral material.	tmpzr1t_l9r_go_relaxed.owl	up regulation of egress of virus within host cell|up regulation of viral egress|positive regulation of egress of virus within host cell|upregulation of movement of virus within host cell|up-regulation of egress of virus within host cell|positive regulation of movement of virus within host cell|upregulation of egress of virus within host cell|up-regulation of movement of virus within host cell|activation of egress of virus within host cell|activation of movement of virus within host cell|activation of viral egress|up-regulation of viral egress|positive regulation of viral egress|upregulation of viral egress|up regulation of movement of virus within host cell							ss	2012-08-09T05:45:54Z					biological_process											owl:Class	
GO:0075733	biolink:NamedThing	intracellular transport of virus	The directed movement of a virus, or part of a virus, within the host cell.	tmpzr1t_l9r_go_relaxed.owl	intracellular transport of viral material|viral egress|viral genome transport in host cell|egress of virus within host cell|intracellular virion transport|movement of virus within host cell							jl	2009-05-01T04:01:33Z			GO:0046796|GO:0046788|GO:0046795		biological_process											owl:Class	
GO:0042092	biolink:NamedThing	type 2 immune response	An immune response which is associated with resistance to extracellular organisms such as helminths and pathological conditions such as allergy, which is orchestrated by the production of particular cytokines, most notably IL-4, IL-5, IL-10, and IL-13, by any of a variety of cell types including T-helper 2 cells, eosinophils, basophils, mast cells, and nuocytes, resulting in enhanced production of certain antibody isotypes and other effects.	tmpzr1t_l9r_go_relaxed.owl	T-helper 2 type immune response|Th2 immune response													biological_process											owl:Class	
GO:0097091	biolink:NamedThing	synaptic vesicle clustering	The process that results in grouping synaptic vesicles in presynaptic structures.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/synapse/issues/163						pr	2011-07-04T01:48:24Z					biological_process											owl:Class	
GO:0099504	biolink:NamedThing	synaptic vesicle cycle	A biological process in which synaptic vesicles are loaded with neurotransmitters, move to the active zone, exocytose and are then recycled via endocytosis, ultimately leading to reloading with neurotransmitters.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1901712	biolink:NamedThing	positive regulation of homoserine biosynthetic process	Any process that activates or increases the frequency, rate or extent of homoserine biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	up regulation of homoserine anabolism|activation of homoserine synthesis|up-regulation of homoserine synthesis|activation of homoserine formation|positive regulation of homoserine anabolism|upregulation of homoserine biosynthesis|up regulation of homoserine synthesis|upregulation of homoserine biosynthetic process|up regulation of homoserine biosynthetic process|upregulation of homoserine anabolism|up regulation of homoserine formation|up-regulation of homoserine biosynthesis|positive regulation of homoserine formation|up-regulation of homoserine formation|up-regulation of homoserine biosynthetic process|upregulation of homoserine formation|positive regulation of homoserine synthesis|upregulation of homoserine synthesis|up-regulation of homoserine anabolism|up regulation of homoserine biosynthesis|activation of homoserine biosynthesis|activation of homoserine anabolism|positive regulation of homoserine biosynthesis|activation of homoserine biosynthetic process							mcc	2012-12-19T16:02:05Z					biological_process											owl:Class	
GO:0009090	biolink:NamedThing	homoserine biosynthetic process	The chemical reactions and pathways resulting in the formation of homoserine, alpha-amino-gamma-hydroxybutyric acid.	tmpzr1t_l9r_go_relaxed.owl	homoserine biosynthesis|homoserine anabolism|homoserine synthesis|homoserine formation				MetaCyc:HOMOSERSYN-PWY									biological_process											owl:Class	
GO:0061213	biolink:NamedThing	positive regulation of mesonephros development	Any process that increases the rate, frequency or extent of mesonephros development. Mesonephros development is the process whose specific outcome is the progression of the mesonephros over time, from its formation to the mature structure. The mesonephros is an organ that filters the blood and excretes the end products of body metabolism in the form of urine.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-08-17T03:39:35Z					biological_process											owl:Class	
GO:2001267	biolink:NamedThing	regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway	Any process that modulates the frequency, rate or extent of cysteine-type endopeptidase activity involved in apoptotic signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	regulation of initiator caspase activity|regulation of cysteine-type endopeptidase activity involved in apoptotic signalling pathway							pr	2011-12-13T07:56:13Z					biological_process											owl:Class	
GO:0035047	biolink:NamedThing	centrosomal and pronuclear rotation	The rotation of centrosomes and associated pronuclei in one-cell embryos such as those of Caenorhabditis elegans, occurring as a transition between pronuclear migration and pronuclear fusion.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0007338	biolink:NamedThing	single fertilization	The union of male and female gametes to form a zygote.	tmpzr1t_l9r_go_relaxed.owl	zygote biosynthesis|zygote formation													biological_process											owl:Class	
GO:1905437	biolink:NamedThing	positive regulation of histone H3-K4 trimethylation	Any process that activates or increases the frequency, rate or extent of histone H3-K4 trimethylation.	tmpzr1t_l9r_go_relaxed.owl	up regulation of histone H3-K4 trimethylation|up-regulation of histone H3-K4 trimethylation|activation of histone H3-K4 trimethylation|upregulation of histone H3-K4 trimethylation							hbye	2016-09-14T13:09:11Z					biological_process											owl:Class	
GO:0046817	biolink:NamedThing	chemokine receptor antagonist activity	Interacts with chemokine receptors to reduce the action of a chemokine.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0051452	biolink:NamedThing	intracellular pH reduction	Any process that reduces the internal pH of a cell, measured by the concentration of the hydrogen ion.	tmpzr1t_l9r_go_relaxed.owl	cell pH reduction|reduction of pH in cell|reduction of cellular pH|cellular acidification|intracellular acidification													biological_process											owl:Class	
GO:0003423	biolink:NamedThing	growth plate cartilage chondrocyte division	The process resulting in the oriented physical partitioning and separation of a chondrocytes in the growth plate.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-12-22T09:55:51Z					biological_process											owl:Class	
GO:0003419	biolink:NamedThing	growth plate cartilage chondrocyte proliferation	The multiplication or reproduction of chondrocytes in a growing endochondral bone, resulting in the expansion of a cell population.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-12-22T09:02:51Z					biological_process											owl:Class	
GO:0007436	biolink:NamedThing	larval salivary gland morphogenesis	The process, occurring in the larva, by which the anatomical structures of the salivary gland are generated and organized.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0002168	biolink:NamedThing	instar larval development	The process whose specific outcome is the progression of the larva over time, from its formation to the mature structure. This begins with the newly hatched first-instar larva, through its maturation to the end of the last larval stage. An example of this process is found in Drosophila melanogaster.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0075304	biolink:NamedThing	negative regulation of basidiospore formation	Any process that stops, prevents, or reduces the frequency, rate or extent of basidiospore formation, a process in which a sexually produced fungal spore is formed on a basidium in the fungi basidiomycetes.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0034295	biolink:NamedThing	basidiospore formation	The process in which spores form outside a specialized end cell known as a basidium. Basidia are characteristic of the basidiomycete fungi (phylum Basidiomycota), and give rise to spores that each contain a haploid nucleus that is the product of meiosis. The spores are usually attached to the basidium by short spikes called sterigmata (singular: sterigma). In most basidiomycetes there are four sterigmata (and four spores) to a basidium.	tmpzr1t_l9r_go_relaxed.owl						Note that basidiospores and basidia are separate biological structures. The basidium is the structure that bear the basidiospores, but the development of the basidium is a different process than the formation of the basidiospores themselves. For this reason, GO:0034295 basidiospore formation and GO:0075313 basidium development are different terms and are not linked.								biological_process											owl:Class	
GO:0060050	biolink:NamedThing	positive regulation of protein glycosylation	Any process that activates or increases the frequency, rate or extent of the glycosylation of one or more amino acid residues within a protein. Protein glycosylation is the addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid, e.g. the addition of glycan chains to proteins.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of protein amino acid glycosylation													biological_process											owl:Class	
GO:1904235	biolink:NamedThing	regulation of substrate-dependent cell migration, cell attachment to substrate	Any process that modulates the frequency, rate or extent of substrate-dependent cell migration, cell attachment to substrate.	tmpzr1t_l9r_go_relaxed.owl	regulation of substrate-bound cell migration, cell attachment to substrate							pga	2015-05-15T13:29:59Z					biological_process											owl:Class	
GO:0098965	biolink:NamedThing	extracellular matrix of synaptic cleft	The portion of the extracellular matrix that lies within the synaptic cleft.	tmpzr1t_l9r_go_relaxed.owl	synaptic cleft ECM|ECM of synaptic cleft													cellular_component											owl:Class	
GO:0099535	biolink:NamedThing	synapse-associated extracellular matrix	The extracellular matrix of the perisynaptic space (the extracellular space adjacent to the synapse) and the synaptic cleft.	tmpzr1t_l9r_go_relaxed.owl	extra-synaptic extracellular matrix													cellular_component											owl:Class	
GO:0007394	biolink:NamedThing	dorsal closure, elongation of leading edge cells	The change in shape of cells at the dorsal-most (leading) edge of the epidermis from being polygonal to being elongated in the dorsal/ventral axis.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1904994	biolink:NamedThing	regulation of leukocyte adhesion to vascular endothelial cell	Any process that modulates the frequency, rate or extent of leukocyte adhesion to vascular endothelial cell.	tmpzr1t_l9r_go_relaxed.owl								bc	2016-03-01T10:59:00Z					biological_process											owl:Class	
GO:0003437	biolink:NamedThing	regulation of cell communication involved in growth plate cartilage morphogenesis	Any process that modulates the frequency, rate or extent of cell communication that contributes to the shaping of the growth plate cartilage.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-12-22T01:34:24Z					biological_process											owl:Class	
GO:0045963	biolink:NamedThing	negative regulation of dopamine metabolic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving dopamine.	tmpzr1t_l9r_go_relaxed.owl	inhibition of dopamine metabolic process|down-regulation of dopamine metabolic process|down regulation of dopamine metabolic process|negative regulation of dopamine metabolism|downregulation of dopamine metabolic process													biological_process											owl:Class	
GO:0042417	biolink:NamedThing	dopamine metabolic process	The chemical reactions and pathways involving dopamine, a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline.	tmpzr1t_l9r_go_relaxed.owl	dopamine metabolism													biological_process											owl:Class	
GO:0086023	biolink:NamedThing	adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process	A series of molecular signals beginning with a G protein-coupled adrenergic cell surface receptor combining with epinephrine or norepinephrine, to activate adenylate cyclase, which contributes to a circulatory system process carried out by the heart.	tmpzr1t_l9r_go_relaxed.owl	adrenergic receptor signalling pathway involved in heart process|adrenergic receptor signaling pathway involved in heart process|beta-adrenergic receptor signalling pathway involved in heart process							tb	2011-11-11T02:51:03Z					biological_process											owl:Class	
GO:2000307	biolink:NamedThing	regulation of tumor necrosis factor (ligand) superfamily member 11 production	Any process that modulates the frequency, rate or extent of tumor necrosis factor (ligand) superfamily member 11 production.	tmpzr1t_l9r_go_relaxed.owl	regulation of RANKL production|regulation of TNFSF11 production							mah	2011-01-17T10:44:00Z					biological_process											owl:Class	
GO:0072535	biolink:NamedThing	tumor necrosis factor (ligand) superfamily member 11 production	The appearance of tumor necrosis factor superfamily member 11 (TNFSF11; RANKL) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	tmpzr1t_l9r_go_relaxed.owl	TNFSF11 production|tumor necrosis factor ligand superfamily member 11 production|RANKL production					Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.		mah	2011-01-14T01:42:23Z					biological_process											owl:Class	
GO:0030313	biolink:NamedThing	cell envelope	An envelope that surrounds a bacterial cell and includes the cytoplasmic membrane and everything external, encompassing the periplasmic space, cell wall, and outer membrane if present.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Cell_envelope									cellular_component											owl:Class	
GO:0004713	biolink:NamedThing	protein tyrosine kinase activity	Catalysis of the reaction: ATP + a protein tyrosine = ADP + protein tyrosine phosphate.	tmpzr1t_l9r_go_relaxed.owl	protein-tyrosine kinase activity				Reactome:R-HSA-451942|Reactome:R-HSA-445091|Reactome:R-HSA-8848077|Reactome:R-HSA-982807|Reactome:R-HSA-8874080|Reactome:R-HSA-388833|Reactome:R-HSA-873924|Reactome:R-HSA-9673756|Reactome:R-HSA-8857555|Reactome:R-HSA-8848124|Reactome:R-HSA-1839112|Reactome:R-HSA-873922|Reactome:R-HSA-2023460|Reactome:R-HSA-2454239|RHEA:10596|Reactome:R-HSA-2730843|Reactome:R-HSA-202216|Reactome:R-HSA-2730884|Reactome:R-HSA-9706344|Reactome:R-HSA-389086|Reactome:R-HSA-2730862|Reactome:R-HSA-2671829|Reactome:R-HSA-191636|Reactome:R-HSA-909718|Reactome:R-HSA-2730851|Reactome:R-HSA-983709|Reactome:R-HSA-3928604|Reactome:R-HSA-171011|Reactome:R-HSA-9699578|Reactome:R-HSA-2395439|Reactome:R-HSA-2029984|Reactome:R-HSA-9012650|Reactome:R-HSA-452100|Reactome:R-HSA-8848776|Reactome:R-HSA-1251922|Reactome:R-HSA-5637795|Reactome:R-HSA-5655284|Reactome:R-HSA-5654634|Reactome:R-HSA-452122|Reactome:R-HSA-5654628|Reactome:R-HSA-9028728|Reactome:R-HSA-3928580|Reactome:R-HSA-879909|Reactome:R-HSA-182969|Reactome:R-HSA-8848818|Reactome:R-HSA-443817|Reactome:R-HSA-9613023|Reactome:R-HSA-9634390|Reactome:R-HSA-452097|Reactome:R-HSA-9672173|Reactome:R-HSA-9664261|Reactome:R-HSA-9604767|Reactome:R-HSA-202233|Reactome:R-HSA-2730882|Reactome:R-HSA-5683930|Reactome:R-HSA-5654655|Reactome:R-HSA-9026464|Reactome:R-HSA-5655341|Reactome:R-HSA-428888|Reactome:R-HSA-177937|Reactome:R-HSA-1839110|Reactome:R-HSA-5690702|Reactome:R-HSA-1250195|Reactome:R-HSA-2424486|Reactome:R-HSA-2424484|Reactome:R-HSA-429441|Reactome:R-HSA-1169421|Reactome:R-HSA-1250348|Reactome:R-HSA-202307|Reactome:R-HSA-8857577|Reactome:R-HSA-8848436|Reactome:R-HSA-9029151|Reactome:R-HSA-6790087|Reactome:R-HSA-388831|Reactome:R-HSA-210872|Reactome:R-HSA-5655301|Reactome:R-HSA-445084|Reactome:R-HSA-8857583|Reactome:R-HSA-9695834|Reactome:R-HSA-9026510|Reactome:R-HSA-9706350|Reactome:R-HSA-4093332|Reactome:R-HSA-1888198|Reactome:R-HSA-9625487|Reactome:R-HSA-1472121|Reactome:R-HSA-5621363|Reactome:R-HSA-9670412|Reactome:R-HSA-9665704|Reactome:R-HSA-2012087|Reactome:R-HSA-1839067|Reactome:R-HSA-9665705|Reactome:R-HSA-9664275|Reactome:R-HSA-3928610|Reactome:R-HSA-5655278|Reactome:R-HSA-3928594|Reactome:R-HSA-9018572|Reactome:R-HSA-389083|Reactome:R-HSA-9665389|Reactome:R-HSA-9672175|Reactome:R-HSA-2586555|Reactome:R-HSA-190429|Reactome:R-HSA-2201322|Reactome:R-HSA-8876948|Reactome:R-HSA-399947|Reactome:R-HSA-8937807|Reactome:R-HSA-9665709|Reactome:R-HSA-210291|Reactome:R-HSA-1307963|Reactome:R-HSA-2730860|Reactome:R-HSA-2029989|Reactome:R-HSA-374701|Reactome:R-HSA-5654147|Reactome:R-HSA-8948143|Reactome:R-HSA-183058|Reactome:R-HSA-8849042|Reactome:R-HSA-9034875|Reactome:R-HSA-389762|Reactome:R-HSA-1433542|Reactome:R-HSA-9027272|Reactome:R-HSA-1839098|Reactome:R-HSA-9666425|Reactome:R-HSA-2730858|Reactome:R-HSA-8874082|Reactome:R-HSA-909726|Reactome:R-HSA-4420206|Reactome:R-HSA-8964252|Reactome:R-HSA-2038387|Reactome:R-HSA-190385|Reactome:R-HSA-1524186|Reactome:R-HSA-9603420|Reactome:R-HSA-391866|Reactome:R-HSA-873919|Reactome:R-HSA-4420121|Reactome:R-HSA-2396594|Reactome:R-HSA-5654151|Reactome:R-HSA-9612085|Reactome:R-HSA-9026890|Reactome:R-HSA-5654578|Reactome:R-HSA-8851890|Reactome:R-HSA-5654653|Reactome:R-HSA-5655270|Reactome:R-HSA-2404199|Reactome:R-HSA-1225952|Reactome:R-HSA-190388|Reactome:R-HSA-1470009|Reactome:R-HSA-508282|Reactome:R-HSA-2029449|Reactome:R-HSA-2029453|Reactome:R-HSA-5654428|Reactome:R-HSA-6784319|Reactome:R-HSA-1295609|Reactome:R-HSA-9011241|Reactome:R-HSA-873918|Reactome:R-HSA-429449|Reactome:R-HSA-190408|Reactome:R-HSA-8875451|Reactome:R-HSA-69195|Reactome:R-HSA-5654631|Reactome:R-HSA-445085|Reactome:R-HSA-174164|Reactome:R-HSA-202291|Reactome:R-HSA-5654407|Reactome:R-HSA-9006332|Reactome:R-HSA-354073|Reactome:R-HSA-8848726|Reactome:R-HSA-6784006|Reactome:R-HSA-377640|Reactome:R-HSA-9027425|Reactome:R-HSA-5654397|Reactome:R-HSA-212710|Reactome:R-HSA-202168|Reactome:R-HSA-2033490|Reactome:R-HSA-202245|Reactome:R-HSA-3928627|Reactome:R-HSA-2033485|Reactome:R-HSA-373750|Reactome:R-HSA-2012073|Reactome:R-HSA-9024726|Reactome:R-HSA-419646|Reactome:R-HSA-2424487|Reactome:R-HSA-1433454|Reactome:R-HSA-8875817|Reactome:R-HSA-202174|Reactome:R-HSA-1433488|Reactome:R-HSA-373747|Reactome:R-HSA-8942607|Reactome:R-HSA-434836|Reactome:R-HSA-202165|Reactome:R-HSA-9027273|Reactome:R-HSA-8956659|Reactome:R-HSA-9034814|Reactome:R-HSA-2395801|Reactome:R-HSA-8848758|Reactome:R-HSA-432129|Reactome:R-HSA-3928583|Reactome:R-HSA-418859|Reactome:R-HSA-2012082|Reactome:R-HSA-8857925|Reactome:R-HSA-4420117|Reactome:R-HSA-5357429|Reactome:R-HSA-9606159|Reactome:R-HSA-205289|Reactome:R-HSA-9669890|Reactome:R-HSA-177930|Reactome:R-HSA-2197698|Reactome:R-HSA-2586553|Reactome:R-HSA-170070|Reactome:R-HSA-8983872|Reactome:R-HSA-5637796|Reactome:R-HSA-1963586|Reactome:R-HSA-9032532|Reactome:R-HSA-5654545|Reactome:R-HSA-9606162|Reactome:R-HSA-5654418|Reactome:R-HSA-8849032|Reactome:R-HSA-9034714|Reactome:R-HSA-5218830|Reactome:R-HSA-8853315|Reactome:R-HSA-177934|Reactome:R-HSA-445076|Reactome:R-HSA-909730|Reactome:R-HSA-2033486|Reactome:R-HSA-909729|Reactome:R-HSA-2730886|Reactome:R-HSA-68954|Reactome:R-HSA-5655268|Reactome:R-HSA-8876230|Reactome:R-HSA-9032854|Reactome:R-HSA-1248655|Reactome:R-HSA-9698005|Reactome:R-HSA-354124|Reactome:R-HSA-8848606|Reactome:R-HSA-5218851|Reactome:R-HSA-2029268|Reactome:R-HSA-190413|Reactome:R-HSA-9664278|Reactome:R-HSA-2033488|Reactome:R-HSA-2730833|Reactome:R-HSA-8853313|Reactome:R-HSA-1839065|Reactome:R-HSA-8849463|Reactome:R-HSA-5218806|Reactome:R-HSA-9665032|Reactome:R-HSA-389354|Reactome:R-HSA-9606163|Reactome:R-HSA-9032601|Reactome:R-HSA-912629|Reactome:R-HSA-391871|Reactome:R-HSA-9021609|Reactome:R-HSA-5218642|Reactome:R-HSA-5654607|Reactome:R-HSA-2038944|Reactome:R-HSA-1982066|Reactome:R-HSA-391156|Reactome:R-HSA-5654149|Reactome:R-HSA-5621370|Reactome:R-HSA-112333|Reactome:R-HSA-6806974|Reactome:R-HSA-2023455|Reactome:R-HSA-202248|Reactome:R-HSA-1168394|Reactome:R-HSA-4420128|Reactome:R-HSA-9032426|Reactome:R-HSA-2730888|Reactome:R-HSA-186786|Reactome:R-HSA-9664976|Reactome:R-HSA-190427|Reactome:R-HSA-8874078|Reactome:R-HSA-1433418|Reactome:R-HSA-5655243|Reactome:R-HSA-8855237|Reactome:R-HSA-9664588|Reactome:R-HSA-1963581|Reactome:R-HSA-9703437|Reactome:R-HSA-399934|Reactome:R-HSA-2130194|Reactome:R-HSA-8849068|Reactome:R-HSA-909732|Reactome:R-HSA-2671742|Reactome:R-HSA-3928578|Reactome:R-HSA-5621355|Reactome:R-HSA-8876246|Reactome:R-HSA-418872|Reactome:R-HSA-1433506|Reactome:R-HSA-5686587|Reactome:R-HSA-5654587|Reactome:R-HSA-8867041|Reactome:R-HSA-2454208|Reactome:R-HSA-5654222|Reactome:R-HSA-1671691|Reactome:R-HSA-8851933|Reactome:R-HSA-8964242|Reactome:R-HSA-9006323|Reactome:R-HSA-372693|Reactome:R-HSA-391865|Reactome:R-HSA-1248694|Reactome:R-HSA-8849102|Reactome:R-HSA-1963582|Reactome:R-HSA-9026579|Reactome:R-HSA-170991|Reactome:R-HSA-9665411|Reactome:R-HSA-983707|Reactome:R-HSA-5218812|Reactome:R-HSA-399946|Reactome:R-HSA-9673761|Reactome:R-HSA-9029155|Reactome:R-HSA-5218828|Reactome:R-HSA-1247844|Reactome:R-HSA-3215391|Reactome:R-HSA-9680248|Reactome:R-HSA-5607745|Reactome:R-HSA-2428926|Reactome:R-HSA-8848005|Reactome:R-HSA-8853325|Reactome:R-HSA-5654582|Reactome:R-HSA-3928648|Reactome:R-HSA-5624486|Reactome:R-HSA-2395412|Reactome:R-HSA-418163|Reactome:R-HSA-5218809|Reactome:R-HSA-879925|Reactome:R-HSA-2404193|Reactome:R-HSA-9670418|Reactome:R-HSA-8937844|Reactome:R-HSA-114600|Reactome:R-HSA-380780|Reactome:R-HSA-170156|Reactome:R-HSA-5654408|Reactome:R-HSA-5654575|Reactome:R-HSA-983703|Reactome:R-HSA-9026502|Reactome:R-HSA-2029459|Reactome:R-HSA-5218820|Reactome:R-HSA-8937728|Reactome:R-HSA-1250315|Reactome:R-HSA-9033284|Reactome:R-HSA-9037040|Reactome:R-HSA-191062|Reactome:R-HSA-9612996|Reactome:R-HSA-9698003|Reactome:R-HSA-190326|Reactome:R-HSA-8853309|Reactome:R-HSA-8847977|Reactome:R-HSA-5607750|Reactome:R-HSA-879907|Reactome:R-HSA-9703438|Reactome:R-HSA-1295540|Reactome:R-HSA-8848873|Reactome:R-HSA-9669911|Reactome:R-HSA-1225960|Reactome:R-HSA-8848975|Reactome:R-HSA-5218640|Reactome:R-HSA-5654605|Reactome:R-HSA-2671850							GO:0004718		molecular_function											owl:Class	
GO:0044853	biolink:NamedThing	plasma membrane raft	A membrane raft that is part of the plasma membrane.	tmpzr1t_l9r_go_relaxed.owl								jl	2014-07-23T15:55:23Z					cellular_component											owl:Class	
GO:0051714	biolink:NamedThing	positive regulation of cytolysis in other organism	Any process that activates or increases the frequency, rate or extent of the cytolysis by an organism of cells in another organism.	tmpzr1t_l9r_go_relaxed.owl	stimulation of cytolysis of cells of another organism|activation of cytolysis of cells of another organism|up regulation of cytolysis of cells of another organism|up-regulation of cytolysis of cells of another organism|upregulation of cytolysis of cells of another organism|positive regulation of cytolysis of cells of another organism|positive regulation of cytolysis of cells of another, non-host, organism											GO:0001904		biological_process											owl:Class	
GO:0051715	biolink:NamedThing	cytolysis in other organism	The killing by an organism of a cell in another organism by means of the rupture of cell membranes and the loss of cytoplasm.	tmpzr1t_l9r_go_relaxed.owl	cytolysis of cells of another organism|cytolysis of cells of another, non-host, organism|cytolysis of cells of competing organism											GO:0001901		biological_process											owl:Class	
GO:0071619	biolink:NamedThing	phosphorylation of RNA polymerase II C-terminal domain serine 2 residues	The process of introducing a phosphate group onto a serine residue at position 2 within the heptapeptide repeat (YSPTSPS) of the C-terminal domain of RNA polymerase II. Typically, phosphorylation of serine 2 (Ser2) occurs subsequent to phosphorylation of serine 5 and is thus seen in the middle and 3' ends of genes. In vivo, Ser2 phosphorylation is primarily performed by CTDK-I in S. cerevisiae or CDK9 in metazoans.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-02-09T02:37:02Z					biological_process											owl:Class	
GO:0002184	biolink:NamedThing	cytoplasmic translational termination	The process resulting in the release of a polypeptide chain from the ribosome in the cytoplasm, usually in response to a termination codon.	tmpzr1t_l9r_go_relaxed.owl								hjd	2011-06-09T03:17:13Z					biological_process											owl:Class	
GO:0072246	biolink:NamedThing	metanephric glomerular parietal epithelial cell development	The process whose specific outcome is the progression of a metanephric glomerular parietal epithelial cell over time, from its formation to the mature structure. Metanephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport.	tmpzr1t_l9r_go_relaxed.owl	metanephric Bowman's capsule development							mah	2010-03-19T03:42:13Z					biological_process											owl:Class	
GO:0072245	biolink:NamedThing	metanephric glomerular parietal epithelial cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a metanephric glomerular parietal epithelial cell. Metanephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-03-19T03:41:26Z					biological_process											owl:Class	
GO:0006859	biolink:NamedThing	extracellular carbohydrate transport	The directed extracellular movement of carbohydrates.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0005576	biolink:NamedThing	extracellular region	The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.	tmpzr1t_l9r_go_relaxed.owl	extracellular				Wikipedia:Extracellular	Note that this term is intended to annotate gene products that are not attached to the cell surface. For gene products from multicellular organisms which are secreted from a cell but retained within the organism (i.e. released into the interstitial fluid or blood), consider the cellular component term 'extracellular space ; GO:0005615'.								cellular_component											owl:Class	
GO:0032157	biolink:NamedThing	prospore contractile ring	A contractile ring, i.e. a cytoskeletal structure composed of actin filaments and myosin, that forms beneath the plasma membrane of the prospore envelope in meiotic cells in preparation for completing cytokinesis.	tmpzr1t_l9r_go_relaxed.owl	meiotic contractile ring|cytokinetic ring|actomyosin ring													cellular_component											owl:Class	
GO:0042764	biolink:NamedThing	ascospore-type prospore	An immature spore undergoing development. The spore usually consists of nucleic acid, prospore membrane(s) that encase the nucleic acid, and ultimately a cell wall that covers the membrane(s). This type of spore is observed in ascospore-forming fungi.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0044493	biolink:NamedThing	envenomation resulting in negative regulation of voltage-gated sodium channel activity in other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant stopping, prevention or reduction of the activity of a voltage-gated sodium channel in the bitten organism.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-02-01T01:26:59Z					biological_process											owl:Class	
GO:2000866	biolink:NamedThing	positive regulation of estradiol secretion	Any process that activates or increases the frequency, rate or extent of estradiol secretion.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of oestradiol secretion							bf	2011-07-26T08:49:20Z					biological_process											owl:Class	
GO:0010227	biolink:NamedThing	floral organ abscission	The controlled shedding of floral organs.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1905902	biolink:NamedThing	regulation of mesoderm formation	Any process that modulates the frequency, rate or extent of mesoderm formation.	tmpzr1t_l9r_go_relaxed.owl								rph	2017-02-03T12:28:20Z					biological_process											owl:Class	
GO:1903525	biolink:NamedThing	regulation of membrane tubulation	Any process that modulates the frequency, rate or extent of membrane tubulation.	tmpzr1t_l9r_go_relaxed.owl	regulation of vesicle scission|regulation of plasma membrane tubulation							pm	2014-10-07T12:52:36Z					biological_process											owl:Class	
GO:0097320	biolink:NamedThing	plasma membrane tubulation	A membrane tubulation process occurring in a plasma membrane.	tmpzr1t_l9r_go_relaxed.owl	membrane tubulation|vesicle scission							pr	2012-05-31T10:01:22Z					biological_process											owl:Class	
GO:1904212	biolink:NamedThing	regulation of iodide transmembrane transport	Any process that modulates the frequency, rate or extent of iodide transmembrane transport.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-05-14T19:00:02Z					biological_process											owl:Class	
GO:1904200	biolink:NamedThing	iodide transmembrane transport	The process in which iodide is transported across a membrane.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-05-08T15:17:19Z					biological_process											owl:Class	
GO:0006288	biolink:NamedThing	base-excision repair, DNA ligation	The ligation by DNA ligase of DNA strands. Ligation occurs after polymerase action to fill the gap left by the action of endonucleases during base-excision repair.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0006284	biolink:NamedThing	base-excision repair	In base excision repair, an altered base is removed by a DNA glycosylase enzyme, followed by excision of the resulting sugar phosphate. The small gap left in the DNA helix is filled in by the sequential action of DNA polymerase and DNA ligase.	tmpzr1t_l9r_go_relaxed.owl	BER				Wikipedia:Base_excision_repair									biological_process											owl:Class	
GO:1905356	biolink:NamedThing	regulation of snRNA pseudouridine synthesis	Any process that modulates the frequency, rate or extent of snRNA pseudouridine synthesis.	tmpzr1t_l9r_go_relaxed.owl								se	2016-08-09T19:12:27Z					biological_process											owl:Class	
GO:0031120	biolink:NamedThing	snRNA pseudouridine synthesis	The intramolecular conversion of uridine to pseudouridine in an snRNA molecule.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1990476	biolink:NamedThing	synaptic vesicle, resting pool	A synaptic vesicle belonging to the pool that remain unreleased even after prolonged stimulation  causes a saturating degree of vesicular turnover.  50-80% of the total number of synaptic vesicles at a resting terminal bouton are in this pool.	tmpzr1t_l9r_go_relaxed.owl	resting pool of synaptic vesicles|reserve pool of synaptic vesicles							pr	2014-09-02T09:12:37Z					cellular_component											owl:Class	
GO:0043195	biolink:NamedThing	terminal bouton	Terminal inflated portion of the axon, containing the specialized apparatus necessary to release neurotransmitters. The axon terminus is considered to be the whole region of thickening and the terminal bouton is a specialized region of it.	tmpzr1t_l9r_go_relaxed.owl	presynaptic bouton|bouton|synaptic bouton|terminal button				NIF_Subcellular:sao187426937									cellular_component											owl:Class	
GO:2000012	biolink:NamedThing	regulation of auxin polar transport	Any process that modulates the frequency, rate or extent of auxin polar transport.	tmpzr1t_l9r_go_relaxed.owl								tb	2010-08-05T11:21:09Z					biological_process											owl:Class	
GO:0009926	biolink:NamedThing	auxin polar transport	The unidirectional movement of auxin in the stem from tip to base along the vector of gravity or basipetally.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1900071	biolink:NamedThing	regulation of sulfite transport	Any process that modulates the frequency, rate or extent of sulfite transport.	tmpzr1t_l9r_go_relaxed.owl	regulation of sulphite transport							dph	2012-01-26T08:41:10Z					biological_process											owl:Class	
GO:0000316	biolink:NamedThing	sulfite transport	The directed movement of sulfite into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	sulphite transport													biological_process											owl:Class	
GO:1901249	biolink:NamedThing	regulation of lung goblet cell differentiation	Any process that modulates the frequency, rate or extent of lung goblet cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	regulation of pulmonary goblet cell differentiation							vk	2012-08-08T08:59:12Z					biological_process											owl:Class	
GO:0060480	biolink:NamedThing	lung goblet cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a lung goblet cell. A goblet cell is a cell of the epithelial lining that produces and secretes mucins.	tmpzr1t_l9r_go_relaxed.owl	pulmonary goblet cell differentiation													biological_process											owl:Class	
GO:0048655	biolink:NamedThing	anther wall tapetum morphogenesis	The process in which the anatomical structures of the anther wall tapetum are generated and organized. The anther wall tapetum is a layer of cells that provides a source of nutrition for the pollen grains as they mature.	tmpzr1t_l9r_go_relaxed.owl	tapetal layer morphogenesis|tapetum morphogenesis|differentiation of tapetal layer													biological_process											owl:Class	
GO:0060809	biolink:NamedThing	mesodermal to mesenchymal transition involved in gastrulation	The epithelial to mesenchymal transition process in which a mesodermal cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell as part of the process of gastrulation.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-08-06T02:42:09Z					biological_process											owl:Class	
GO:0007453	biolink:NamedThing	clypeo-labral disc morphogenesis	The process in which the anatomical structures derived from the clypeo-labral disc are generated and organized. This includes the transformation of a clypeo-labal imaginal disc from a monolayered epithelium in the larvae of holometabolous insects into recognizable adult structures including the labrum, anterior and posterior cibarial plates, fish trap bristles, epistomal sclerite and clypeus.	tmpzr1t_l9r_go_relaxed.owl	morphogenesis of structures derived from the clypeo-labral disc|clypeo-labral disc metamorphosis													biological_process											owl:Class	
GO:0035213	biolink:NamedThing	clypeo-labral disc development	The process whose specific outcome is the progression of the clypeo-labral disc over time, from its formation to the metamorphosis to form adult structures. The clypeo-labral disc develops into the labrum, anterior cibarial plate, fish trap bristles, epistomal sclerite.	tmpzr1t_l9r_go_relaxed.owl	development of structures derived from the clypeo-labral disc													biological_process											owl:Class	
GO:0090376	biolink:NamedThing	seed trichome differentiation	The process in which a relatively unspecialized epidermal cell acquires the specialized features of a seed trichome. A seed trichome is a trichome that develops from seed coat epidermis and is often long with putative dispersal function.	tmpzr1t_l9r_go_relaxed.owl	cotton fiber development|seed hair differentiation|seed trichome development							tb	2010-09-15T02:07:10Z					biological_process											owl:Class	
GO:1903051	biolink:NamedThing	negative regulation of proteolysis involved in cellular protein catabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of proteolysis involved in cellular protein catabolic process.	tmpzr1t_l9r_go_relaxed.owl	downregulation of proteolysis during cellular protein catabolism|down-regulation of peptidolysis involved in cellular protein catabolism|down regulation of proteolysis involved in cellular protein catabolic process|downregulation of peptidolysis involved in cellular protein catabolic process|inhibition of proteolysis during cellular protein catabolic process|negative regulation of peptidolysis during cellular protein catabolism|inhibition of peptidolysis during cellular protein catabolic process|down-regulation of proteolysis during cellular protein catabolic process|inhibition of peptidolysis during cellular protein catabolism|down-regulation of peptidolysis during cellular protein catabolic process|down regulation of peptidolysis during cellular protein catabolism|downregulation of peptidolysis during cellular protein catabolism|down regulation of proteolysis during cellular protein catabolic process|negative regulation of peptidolysis involved in cellular protein catabolic process|negative regulation of peptidolysis during cellular protein catabolic process|negative regulation of peptidolysis involved in cellular protein catabolism|downregulation of proteolysis involved in cellular protein catabolic process|down-regulation of proteolysis during cellular protein catabolism|down-regulation of peptidolysis during cellular protein catabolism|inhibition of peptidolysis involved in cellular protein catabolic process|downregulation of proteolysis during cellular protein catabolic process|inhibition of peptidolysis involved in cellular protein catabolism|inhibition of proteolysis during cellular protein catabolism|down regulation of peptidolysis during cellular protein catabolic process|downregulation of peptidolysis involved in cellular protein catabolism|down-regulation of proteolysis involved in cellular protein catabolic process|negative regulation of proteolysis during cellular protein catabolic process|down-regulation of peptidolysis involved in cellular protein catabolic process|down regulation of proteolysis during cellular protein catabolism|down regulation of peptidolysis involved in cellular protein catabolic process|negative regulation of proteolysis during cellular protein catabolism|downregulation of peptidolysis during cellular protein catabolic process|inhibition of proteolysis involved in cellular protein catabolic process|down regulation of peptidolysis involved in cellular protein catabolism					Overexpression of cathepsin C propeptide significantly increased the degradation of intestinal alkaline phosphatase (IAP).		rl	2014-05-22T18:00:51Z					biological_process											owl:Class	
GO:0098890	biolink:NamedThing	extrinsic component of postsynaptic membrane	The component of the postsynaptic membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0045211	biolink:NamedThing	postsynaptic membrane	A specialized area of membrane facing the presynaptic membrane on the tip of the nerve ending and separated from it by a minute cleft (the synaptic cleft). Neurotransmitters cross the synaptic cleft and transmit the signal to the postsynaptic membrane.	tmpzr1t_l9r_go_relaxed.owl	post-synaptic membrane													cellular_component											owl:Class	
GO:1901330	biolink:NamedThing	negative regulation of odontoblast differentiation	Any process that stops, prevents or reduces the frequency, rate or extent of odontoblast differentiation.	tmpzr1t_l9r_go_relaxed.owl	downregulation of odontoblast differentiation|down-regulation of odontoblast differentiation|down regulation of odontoblast differentiation|inhibition of odontoblast differentiation							hjd	2012-08-31T16:50:27Z					biological_process											owl:Class	
GO:0071895	biolink:NamedThing	odontoblast differentiation	The process in which a relatively unspecialized cell of neural crest origin acquires the specialized features of an odontoblast, a cell on the outer surface of the dental pulp whose biological function is the creation of dentin.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-09-14T04:00:40Z					biological_process											owl:Class	
GO:0061152	biolink:NamedThing	trachea submucosa development	The progression of the trachea submucosa over time from its formation to the mature structure. The trachea submucosa is made up of the glands and elastic tissue that lie under the mucosa in the trachea.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-06-07T09:58:40Z					biological_process											owl:Class	
GO:0060438	biolink:NamedThing	trachea development	The process whose specific outcome is the progression of a trachea over time, from its formation to the mature structure. The trachea is the portion of the airway that attaches to the bronchi as it branches.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0061620	biolink:NamedThing	glycolytic process through glucose-6-phosphate	The chemical reactions and pathways resulting in the breakdown of a carbohydrate into pyruvate, occurring through a glucose-6-phosphate intermediate, with the concomitant production of a small amount of ATP.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:GLYCOLYSIS			dph	2014-04-14T09:17:48Z					biological_process											owl:Class	
GO:0004347	biolink:NamedThing	glucose-6-phosphate isomerase activity	Catalysis of the reaction: D-glucose 6-phosphate = D-fructose 6-phosphate.	tmpzr1t_l9r_go_relaxed.owl	phosphoglucoisomerase activity|D-glucose-6-phosphate ketol-isomerase activity|phosphosaccharomutase activity|phosphohexomutase activity|hexose monophosphate isomerase activity|D-glucose-6-phosphate aldose-ketose-isomerase activity|phosphohexoisomerase activity|hexosephosphate isomerase activity|oxoisomerase activity|phosphohexose isomerase activity|glucose phosphate isomerase activity|hexose phosphate isomerase activity|phosphoglucose isomerase activity				MetaCyc:PGLUCISOM-RXN|Reactome:R-HSA-70471|EC:5.3.1.9|RHEA:11816|Reactome:R-HSA-70475									molecular_function											owl:Class	
GO:0070935	biolink:NamedThing	3'-UTR-mediated mRNA stabilization	An mRNA stabilization process in which one or more RNA-binding proteins associate with the 3'-untranslated region (UTR) of an mRNA.	tmpzr1t_l9r_go_relaxed.owl	3'-untranslated region-mediated mRNA stabilization							mah	2009-09-21T03:08:20Z					biological_process											owl:Class	
GO:1990600	biolink:NamedThing	single-stranded DNA endodeoxyribonuclease activator activity	Increases the activity of a single-stranded DNA endodeoxyribonuclease activator activity.	tmpzr1t_l9r_go_relaxed.owl								al	2015-01-06T15:35:36Z					molecular_function											owl:Class	
GO:0032436	biolink:NamedThing	positive regulation of proteasomal ubiquitin-dependent protein catabolic process	Any process that activates or increases the frequency, rate or extent of the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome.	tmpzr1t_l9r_go_relaxed.owl	upregulation of proteasomal ubiquitin-dependent protein catabolic process|stimulation of proteasomal ubiquitin-dependent protein catabolic process|up regulation of proteasomal ubiquitin-dependent protein catabolic process|activation of proteasomal ubiquitin-dependent protein catabolic process|up-regulation of proteasomal ubiquitin-dependent protein catabolic process													biological_process											owl:Class	
GO:0060822	biolink:NamedThing	transforming growth factor beta receptor signaling pathway involved in axial mesodermal cell fate specification	The series of molecular signals generated as a consequence of a transforming growth factor beta receptor binding to one of its physiological ligands and ultimately resulting in the specification of an axial mesodermal fate.	tmpzr1t_l9r_go_relaxed.owl	transforming growth factor beta receptor signalling pathway involved in axial mesodermal cell fate specification							dph	2009-08-11T12:55:33Z					biological_process											owl:Class	
GO:0048327	biolink:NamedThing	axial mesodermal cell fate specification	The process in which a cell becomes capable of differentiating autonomously into an axial mesoderm cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.	tmpzr1t_l9r_go_relaxed.owl	axial mesoderm cell fate specification													biological_process											owl:Class	
GO:0048448	biolink:NamedThing	stamen morphogenesis	The process in which the anatomical structures of the stamen are generated and organized.	tmpzr1t_l9r_go_relaxed.owl												GO:0048426		biological_process											owl:Class	
GO:0110059	biolink:NamedThing	negative regulation of blood vessel endothelial cell differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of blood vessel endothelial cell differentiation.	tmpzr1t_l9r_go_relaxed.owl								kmv	2017-10-23T14:47:29Z					biological_process											owl:Class	
GO:0060837	biolink:NamedThing	blood vessel endothelial cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a blood vessel endothelial cell, a thin flattened cell that lines the inside surfaces of blood vessels.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-08-11T03:47:36Z					biological_process											owl:Class	
GO:0075025	biolink:NamedThing	initiation of appressorium formation	The process in which a relatively unspecialized cell starts to acquire specialized features of the symbiont appressorium to aid in infection of the host. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	appressorium initiation on or near host|initiation of appressorium on or near host|initiation of symbiont appressorium on or near host|initiation of appressorium by symbiont on or near host					Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products from the symbiont involved in this process.								biological_process											owl:Class	
GO:0004535	biolink:NamedThing	poly(A)-specific ribonuclease activity	Catalysis of the exonucleolytic cleavage of poly(A) to 5'-AMP.	tmpzr1t_l9r_go_relaxed.owl	3'-exoribonuclease activity|2',3'-exoribonuclease activity|poly(A)-specific RNase activity				Reactome:R-HSA-429992|EC:3.1.13.4|Reactome:R-HSA-429955|Reactome:R-HSA-430021|MetaCyc:3.1.13.4-RXN									molecular_function											owl:Class	
GO:0048090	biolink:NamedThing	negative regulation of female pigmentation	Any process that stops, prevents, or reduces the frequency, rate or extent of establishment of a pattern of pigment in females.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of female pigmentation|down regulation of female pigmentation|inhibition of female pigmentation|downregulation of female pigmentation													biological_process											owl:Class	
GO:0048095	biolink:NamedThing	female pigmentation	Establishment of a pattern of pigment in females.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1904088	biolink:NamedThing	positive regulation of epiboly involved in gastrulation with mouth forming second	Any process that activates or increases the frequency, rate or extent of epiboly involved in gastrulation with mouth forming second.	tmpzr1t_l9r_go_relaxed.owl	activation of epiboly involved in gastrulation with mouth forming second|upregulation of epiboly involved in gastrulation with mouth forming second|up regulation of epiboly involved in gastrulation with mouth forming second|up-regulation of epiboly involved in gastrulation with mouth forming second							dos	2015-03-25T11:17:47Z					biological_process											owl:Class	
GO:0055113	biolink:NamedThing	epiboly involved in gastrulation with mouth forming second	The expansion of one cell sheet over other cells involved in deuterostomic gastrulation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0048493	biolink:NamedThing	plasma membrane-derived thylakoid ribulose bisphosphate carboxylase complex	A complex, located in the plasma membrane-derived thylakoid, containing either both large and small subunits or just small subunits. It carries out the activity of producing 3-phosphoglycerate from carbon dioxide and ribulose-1,5-bisphosphate.	tmpzr1t_l9r_go_relaxed.owl	ribulose bisphosphate carboxylase complex|RubisCO complex|plasma membrane ribulose bisphosphate carboxylase complex													cellular_component											owl:Class	
GO:0030075	biolink:NamedThing	bacterial thylakoid	A thylakoid that is derived from and attached to, but not necessarily continuous with, the plasma membrane, and is not enclosed in a plastid. It bears the photosynthetic pigments in photosynthetic cyanobacteria.	tmpzr1t_l9r_go_relaxed.owl	plasma membrane-derived thylakoid													cellular_component											owl:Class	
GO:1990780	biolink:NamedThing	cytoplasmic side of dendritic spine plasma membrane	The leaflet of the plasma membrane that faces the cytoplasm and any proteins embedded or anchored in it or attached to its surface surrounding a dendritic spine.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-06-23T18:35:39Z					cellular_component											owl:Class	
GO:0032591	biolink:NamedThing	dendritic spine membrane	The portion of the plasma membrane surrounding a dendritic spine.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0042701	biolink:NamedThing	progesterone secretion	The regulated release of progesterone, a steroid hormone, by the corpus luteum of the ovary and by the placenta.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1902412	biolink:NamedThing	regulation of mitotic cytokinesis	Any process that modulates the frequency, rate or extent of mitotic cytokinesis.	tmpzr1t_l9r_go_relaxed.owl	regulation of cytokinesis after mitosis							jl	2013-09-12T14:11:49Z					biological_process											owl:Class	
GO:0021732	biolink:NamedThing	midbrain-hindbrain boundary maturation	A developmental process, independent of morphogenetic (shape) change, that is required for the midbrain-hindbrain boundary to attain its fully functional state. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate.	tmpzr1t_l9r_go_relaxed.owl	isthmus maturation|MHB maturation													biological_process											owl:Class	
GO:0034446	biolink:NamedThing	substrate adhesion-dependent cell spreading	The morphogenetic process that results in flattening of a cell as a consequence of its adhesion to a substrate.	tmpzr1t_l9r_go_relaxed.owl	cell spreading during cell substrate adhesion|substrate adhesion dependent cell spreading													biological_process											owl:Class	
GO:1903774	biolink:NamedThing	positive regulation of viral budding via host ESCRT complex	Any process that activates or increases the frequency, rate or extent of viral budding via host ESCRT complex.	tmpzr1t_l9r_go_relaxed.owl	up regulation of viral budding via host ESCRT complex|up regulation of viral budding through the ESCRT machinery|up-regulation of viral budding through the ESCRT machinery|up-regulation of viral budding via host ESCRT complex|upregulation of viral budding via host ESCRT complex|positive regulation of viral budding through the ESCRT machinery|activation of viral budding through the ESCRT machinery|upregulation of viral budding through the ESCRT machinery|activation of viral budding via host ESCRT complex							als	2015-01-06T16:21:02Z					biological_process											owl:Class	
GO:0039702	biolink:NamedThing	viral budding via host ESCRT complex	Viral budding which uses a host ESCRT protein complex, or complexes, to mediate the budding process.	tmpzr1t_l9r_go_relaxed.owl	host-assisted viral budding|viral budding through the ESCRT machinery				VZ:1536			bf	2013-11-06T16:51:53Z					biological_process											owl:Class	
GO:0021694	biolink:NamedThing	cerebellar Purkinje cell layer formation	The process that gives rise to the cerebellar Purkinje cell layer. This process pertains to the initial formation of a structure from unspecified parts. The Purkinje cell layer lies just underneath the molecular layer of the cerebellar cortex. It contains the neuronal cell bodies of the Purkinje cells that are arranged side by side in a single layer. Candelabrum interneurons are vertically oriented between the Purkinje cells. Purkinje neurons are inhibitory and provide the output of the cerebellar cortex through axons that project into the white matter. Extensive dendritic trees from the Purkinje cells extend upward in a single plane into the molecular layer where they synapse with parallel fibers of granule cells.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0031603	biolink:NamedThing	cytosolic proteasome core complex	The core complex of a proteasome located in the cytosol of a cell.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0061146	biolink:NamedThing	Peyer's patch morphogenesis	The process in which a Peyer's patch is generated and organized. Peyer's patches are typically found as nodules associated with gut epithelium with distinct internal structures including B- and T-zones for the activation of lymphocytes.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-05-26T06:46:23Z					biological_process											owl:Class	
GO:0048541	biolink:NamedThing	Peyer's patch development	The process whose specific outcome is the progression of Peyer's patches over time, from their formation to the mature structure. Peyer's patches are typically found as nodules associated with gut epithelium with distinct internal structures including B- and T-zones for the activation of lymphocytes.	tmpzr1t_l9r_go_relaxed.owl	gut-associated lymphoid tissue development|GALT development													biological_process											owl:Class	
GO:0035167	biolink:NamedThing	larval lymph gland hemopoiesis	The production of blood cells from the larval lymph gland. The lymph gland consists of three to six bilaterally paired lobes that are attached to the cardioblasts during larval stages, and it degenerates during pupal stages.	tmpzr1t_l9r_go_relaxed.owl	larval lymph gland haematopoiesis|larval lymph gland hematopoiesis|larval lymph gland haemopoiesis													biological_process											owl:Class	
GO:0048542	biolink:NamedThing	lymph gland development	The process whose specific outcome is the progression of the lymph gland over time, from its formation to the mature structure. The lymph gland is one of the sites of hemocyte differentiation. It consists of three to six bilaterally paired lobes that are attached to the cardioblasts during larval stages, and it degenerates during pupal stages.	tmpzr1t_l9r_go_relaxed.owl	hematopoietic organ development|hemopoietic organ development|haematopoietic organ development|haemopoietic organ development													biological_process											owl:Class	
GO:2000555	biolink:NamedThing	negative regulation of T-helper 1 cell cytokine production	Any process that stops, prevents or reduces the frequency, rate or extent of T-helper 1 cell cytokine production.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of Th1 cell cytokine production							ebc	2011-04-03T07:35:51Z					biological_process											owl:Class	
GO:0035744	biolink:NamedThing	T-helper 1 cell cytokine production	Any process that contributes to cytokine production by a T-helper 1 cell.	tmpzr1t_l9r_go_relaxed.owl	Th1 cell cytokine production					Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.		bf	2011-03-17T02:22:54Z					biological_process											owl:Class	
GO:1904281	biolink:NamedThing	positive regulation of transcription by RNA polymerase V	Any process that activates or increases the frequency, rate or extent of transcription mediated by RNA polymerase V.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of transcription from RNA polymerase V promoter|positive regulation of transcription from RNA pol V promoter|activation of transcription from RNA pol V promoter|upregulation of transcription from RNA pol V promoter|activation of transcription from RNA polymerase V promoter|positive regulation of transcription from RNA polymerase V promoter|upregulation of transcription from RNA polymerase V promoter|up-regulation of transcription from RNA pol V promoter|up regulation of transcription from RNA polymerase V promoter|up regulation of transcription from RNA pol V promoter							tb	2015-06-03T22:02:00Z					biological_process											owl:Class	
GO:0001060	biolink:NamedThing	transcription by RNA polymerase V	The synthesis of RNA from a DNA template by RNA polymerase V, originating at a Pol V-specific promoter.	tmpzr1t_l9r_go_relaxed.owl	transcription from RNA pol V promoter|transcription from RNA polymerase V promoter	https://github.com/geneontology/go-ontology/issues/14854						krc	2010-09-23T03:54:04Z					biological_process											owl:Class	
GO:0019767	biolink:NamedThing	IgE receptor activity	Combining with an immunoglobulin of the IgE isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0019863	biolink:NamedThing	IgE binding	Binding to an immunoglobulin of the IgE isotype.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0035432	biolink:NamedThing	positive regulation of gluconate transmembrane transport	Any process that activates or increases the frequency, rate or extent of the directed movement of gluconate across a membrane by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	stimulation of gluconate transport|up regulation of gluconate transport|induction of gluconate transport|activation of gluconate transport|positive regulation of gluconate transport|positive regulation of gluconate membrane transport|upregulation of gluconate transport|up-regulation of gluconate transport							bf	2010-04-08T10:39:58Z			GO:0032895		biological_process											owl:Class	
GO:0035429	biolink:NamedThing	gluconate transmembrane transport	The process in which gluconate is transported across a membrane. Gluconate is the aldonic acid derived from glucose.	tmpzr1t_l9r_go_relaxed.owl	gluconate membrane transport|gluconate transport					Note that this term is not intended for use in annotating lateral movement within membranes.		bf	2010-04-08T10:33:46Z			GO:0015725		biological_process											owl:Class	
GO:0032929	biolink:NamedThing	negative regulation of superoxide anion generation	Any process that stops, prevents, or reduces the frequency, rate or extent of enzymatic generation of superoxide by a cell.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of superoxide release|down-regulation of superoxide release|downregulation of superoxide release|inhibition of superoxide release|down regulation of superoxide release													biological_process											owl:Class	
GO:0042554	biolink:NamedThing	superoxide anion generation	The enzymatic generation of superoxide, the superoxide anion O2- (superoxide free radical), or any compound containing this species, by a cell in response to environmental stress, thereby mediating the activation of various stress-inducible signaling pathways.	tmpzr1t_l9r_go_relaxed.owl	superoxide release													biological_process											owl:Class	
GO:0002524	biolink:NamedThing	hypersensitivity	An inflammatory response to an exogenous environmental antigen or an endogenous antigen initiated by the adaptive immune system.	tmpzr1t_l9r_go_relaxed.owl	hypersensitivity response				Wikipedia:Hypersensitivity									biological_process											owl:Class	
GO:0008987	biolink:NamedThing	quinolinate synthetase A activity	Catalysis of the reaction: iminoaspartate + dihydroxy-acetone-phosphate = quinolinate + 2 H2O + phosphate.	tmpzr1t_l9r_go_relaxed.owl					RHEA:25888|MetaCyc:QUINOLINATE-SYNTHA-RXN									molecular_function											owl:Class	
GO:0019805	biolink:NamedThing	quinolinate biosynthetic process	The chemical reactions and pathways resulting in the formation of quinolinate, the anion of quinolinic acid, also known as 2,3-pyridinedicarboxylic acid.	tmpzr1t_l9r_go_relaxed.owl	quinolinate formation|quinolinate anabolism|quinolinate biosynthesis|quinolinate synthesis													biological_process											owl:Class	
GO:0072151	biolink:NamedThing	mesangial cell fate commitment	The process in which the developmental fate of a cell becomes restricted such that it will develop into a mesangial cell.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-02-24T02:11:13Z					biological_process											owl:Class	
GO:1904733	biolink:NamedThing	negative regulation of electron transfer activity	Any process that stops, prevents or reduces the frequency, rate or extent of electron transfer activity.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of thioredoxin-like 2Fe-2S ferredoxin|down regulation of electron transfer flavoprotein, group I|negative regulation of polyferredoxin|down-regulation of electron donor activity|negative regulation of electron transfer flavoprotein, group I|down regulation of 3Fe-4S/4Fe-4S electron transfer carrier|down regulation of chloroplast-type ferredoxin|inhibition of amicyanin|down-regulation of amicyanin|inhibition of electron transfer flavoprotein, group I|downregulation of copper electron carrier|negative regulation of azurin|down regulation of rubredoxin|negative regulation of redox-active disulfide bond electron carrier|negative regulation of iron-sulfur electron transfer carrier|down regulation of adrenodoxin-type ferredoxin|down regulation of redox-active disulfide bond electron carrier|downregulation of electron carrier activity|downregulation of electron transfer flavoprotein|negative regulation of electron acceptor activity|down regulation of electron transfer flavoprotein, group II|inhibition of electron transfer flavoprotein, group II|inhibition of copper electron carrier|down regulation of monocluster bacterial-type ferredoxin|down regulation of polyferredoxin|downregulation of high-potential iron-sulfur carrier|downregulation of amicyanin|down regulation of electron donor activity|down-regulation of iron-sulfur electron transfer carrier|inhibition of high-potential iron-sulfur carrier|downregulation of chloroplast-type ferredoxin|downregulation of bacterial-type ferredoxin|inhibition of monocluster bacterial-type ferredoxin|inhibition of 2Fe-2S electron transfer carrier|down-regulation of electron transfer flavoprotein, group II|down-regulation of electron carrier, chlorophyll electron transport system|downregulation of iron-sulfur electron transfer carrier|down-regulation of chloroplast-type ferredoxin|downregulation of small blue copper electron carrier|negative regulation of 2Fe-2S electron transfer carrier|down-regulation of copper electron carrier|negative regulation of adrenodoxin-type ferredoxin|down-regulation of redox-active disulfide bond electron carrier|down regulation of iron-sulfur electron transfer carrier|inhibition of mononuclear iron electron carrier|inhibition of redox-active disulfide bond electron carrier|down-regulation of electron transfer flavoprotein|inhibition of thioredoxin-like 2Fe-2S ferredoxin|down regulation of small blue copper electron carrier|down regulation of electron acceptor activity|negative regulation of dicluster bacterial-type ferredoxin|downregulation of rubredoxin|downregulation of 2Fe-2S electron transfer carrier|negative regulation of electron transfer flavoprotein, group II|down-regulation of electron carrier activity|downregulation of azurin|downregulation of electron transfer flavoprotein, group I|downregulation of thioredoxin-like 2Fe-2S ferredoxin|negative regulation of chloroplast-type ferredoxin|negative regulation of electron transfer flavoprotein|negative regulation of copper electron carrier|down-regulation of electron acceptor activity|down regulation of thioredoxin-like 2Fe-2S ferredoxin|negative regulation of electron donor activity|down regulation of amicyanin|downregulation of electron carrier, chlorophyll electron transport system|inhibition of electron donor activity|down regulation of electron carrier activity|inhibition of rubredoxin|negative regulation of thioredoxin-like 2Fe-2S ferredoxin|down regulation of dicluster bacterial-type ferredoxin|downregulation of electron donor activity|negative regulation of high-potential iron-sulfur carrier|inhibition of electron carrier, chlorophyll electron transport system|down-regulation of dicluster bacterial-type ferredoxin|down-regulation of monocluster bacterial-type ferredoxin|inhibition of electron transfer flavoprotein|down-regulation of small blue copper electron carrier|down regulation of electron transfer flavoprotein|negative regulation of mononuclear iron electron carrier|down regulation of 2Fe-2S electron transfer carrier|downregulation of electron transfer flavoprotein, group II|negative regulation of bacterial-type ferredoxin|down-regulation of 2Fe-2S electron transfer carrier|downregulation of 3Fe-4S/4Fe-4S electron transfer carrier|inhibition of electron transporter activity|negative regulation of monocluster bacterial-type ferredoxin|inhibition of azurin|down regulation of azurin|down regulation of electron transporter activity|negative regulation of rubredoxin|inhibition of polyferredoxin|downregulation of dicluster bacterial-type ferredoxin|downregulation of polyferredoxin|inhibition of iron-sulfur electron transfer carrier|down-regulation of adrenodoxin-type ferredoxin|down-regulation of azurin|downregulation of electron acceptor activity|negative regulation of amicyanin|down regulation of bacterial-type ferredoxin|down-regulation of high-potential iron-sulfur carrier|down-regulation of polyferredoxin|down-regulation of electron transfer flavoprotein, group I|down regulation of copper electron carrier|negative regulation of electron transporter activity|negative regulation of electron carrier, chlorophyll electron transport system|inhibition of 3Fe-4S/4Fe-4S electron transfer carrier|down-regulation of 3Fe-4S/4Fe-4S electron transfer carrier|downregulation of redox-active disulfide bond electron carrier|down regulation of high-potential iron-sulfur carrier|down-regulation of rubredoxin|inhibition of electron carrier activity|inhibition of electron acceptor activity|inhibition of small blue copper electron carrier|downregulation of adrenodoxin-type ferredoxin|down-regulation of mononuclear iron electron carrier|down regulation of mononuclear iron electron carrier|negative regulation of small blue copper electron carrier|inhibition of adrenodoxin-type ferredoxin|down regulation of electron carrier, chlorophyll electron transport system|inhibition of bacterial-type ferredoxin|downregulation of electron transporter activity|down-regulation of electron transporter activity|downregulation of mononuclear iron electron carrier|inhibition of dicluster bacterial-type ferredoxin|down-regulation of bacterial-type ferredoxin|downregulation of monocluster bacterial-type ferredoxin|negative regulation of 3Fe-4S/4Fe-4S electron transfer carrier|inhibition of chloroplast-type ferredoxin							lb	2015-10-15T07:51:26Z					biological_process											owl:Class	
GO:0003878	biolink:NamedThing	ATP citrate synthase activity	Catalysis of the reaction: acetyl-CoA + ADP + H(+) + oxaloacetate + phosphate = ATP + citrate + CoA.	tmpzr1t_l9r_go_relaxed.owl	ATP-citric lyase activity|ATP:citrate oxaloacetate-lyase [(pro-S)-CH2COO-rightacetyl-CoA] (ATP-dephosphorylating)|ATP-citrate (pro-S-)-lyase activity|citrate-ATP lyase activity|citric cleavage enzyme activity|acetyl-CoA:oxaloacetate C-acetyltransferase [(pro-S)-carboxymethyl-forming, ADP-phosphorylating]|acetyl-CoA:oxaloacetate acetyltransferase (isomerizing; ADP-phosphorylating)|ATP-citrate (pro-S)-lyase activity|ATP:citrate oxaloacetate-lyase ((pro-S)-CH(2)COO(-)->acetyl-CoA) (ATP- dephosphorylating) activity|acetyl-CoA:oxaloacetate acetyltransferase (isomerizing; ADP- phosphorylating) activity|citrate cleavage enzyme activity|ATP citrate (pro-S)-lyase activity|adenosine triphosphate citrate lyase activity				MetaCyc:ATP-CITRATE-PRO-S--LYASE-RXN|Reactome:R-HSA-75848|KEGG_REACTION:R00352|RHEA:21160|EC:2.3.3.8|MetaCyc:PWY-5172	Note that this function was formerly EC:4.1.3.8.						GO:0046913		molecular_function											owl:Class	
GO:0031284	biolink:NamedThing	positive regulation of guanylate cyclase activity	Any process that activates or increases the frequency, rate or extent of guanylate cyclase activity.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of guanylate cyclase activity|activation of guanylate cyclase activity|upregulation of guanylate cyclase activity|up regulation of guanylate cyclase activity|stimulation of guanylate cyclase activity													biological_process											owl:Class	
GO:0019230	biolink:NamedThing	proprioception	The series of events by which an organism senses the position, location, orientation, and movement of the body and its parts. Proprioception is mediated by proprioceptors, sensory nerve terminals found in muscles, tendons, and joint capsules, which give information concerning movements and position of the body. The receptors in the labyrinth are sometimes also considered proprioceptors.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Proprioception									biological_process											owl:Class	
GO:0050884	biolink:NamedThing	neuromuscular process controlling posture	Any process in which an organism voluntarily modulates its posture, the alignment of its anatomical parts.	tmpzr1t_l9r_go_relaxed.owl	regulation of posture													biological_process											owl:Class	
GO:0032252	biolink:NamedThing	secretory granule localization	Any process in which a secretory granule is transported to, and/or maintained in, a specific location within the cell.	tmpzr1t_l9r_go_relaxed.owl	secretory granule localisation|secretory granule clustering													biological_process											owl:Class	
GO:0045616	biolink:NamedThing	regulation of keratinocyte differentiation	Any process that modulates the frequency, rate or extent of keratinocyte differentiation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0035014	biolink:NamedThing	phosphatidylinositol 3-kinase regulator activity	Modulates the activity of any of the phosphatidylinositol 3-kinases (PI3Ks). Regulatory subunits can link a PI3K catalytic subunit to upstream signaling events and help position the catalytic subunits close to their lipid substrates.	tmpzr1t_l9r_go_relaxed.owl	PI3K regulator activity|phosphoinositide 3-kinase regulator activity					See also the molecular function term 'phosphoinositide 3-kinase activity ; GO:0035004'.								molecular_function											owl:Class	
GO:0036313	biolink:NamedThing	phosphatidylinositol 3-kinase catalytic subunit binding	Binding to the catalytic subunit of a phosphatidylinositol 3-kinase. The catalytic subunit catalyzes the addition of a phosphate group to an inositol lipid at the 3' position of the inositol ring.	tmpzr1t_l9r_go_relaxed.owl	PI3K catalytic subunit binding|p110 binding							bf	2012-08-16T10:58:45Z					molecular_function											owl:Class	
GO:0000957	biolink:NamedThing	mitochondrial RNA catabolic process	The chemical reactions and pathways resulting in the breakdown of RNA transcribed from the mitochondrial genome and occurring in the mitochondrion.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1904182	biolink:NamedThing	regulation of pyruvate dehydrogenase activity	Any process that modulates the frequency, rate or extent of pyruvate dehydrogenase activity.	tmpzr1t_l9r_go_relaxed.owl	regulation of pyruvic acid dehydrogenase activity|regulation of pyruvic dehydrogenase activity							dph	2015-05-05T14:17:27Z					biological_process											owl:Class	
GO:2000170	biolink:NamedThing	positive regulation of peptidyl-cysteine S-nitrosylation	Any process that activates or increases the frequency, rate or extent of peptidyl-cysteine S-nitrosylation.	tmpzr1t_l9r_go_relaxed.owl								rl	2010-10-07T10:49:35Z					biological_process											owl:Class	
GO:0090733	biolink:NamedThing	tenascin complex	A extracellular matrix complex involved in cell adhesion and cell migration. Typically homotrimeric or homohexameric. In mammals, four complexes exist: Tenascin-C, Tenascin-N (also known as Tenascin-W), Tenascin-X and Tenascin-R.	tmpzr1t_l9r_go_relaxed.owl	Tenascin-W|Tenascin-X|Tenascin-R|Tenascin-N|Tenascin-C					An example is Tenascin-N (Q9UQP3) in PMID:17909022 (IDA).		tb	2017-02-01T16:29:55Z					cellular_component											owl:Class	
GO:0008020	biolink:NamedThing	G protein-coupled photoreceptor activity	Combining with incidental electromagnetic radiation, particularly visible light, and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.	tmpzr1t_l9r_go_relaxed.owl	G protein coupled photoreceptor activity|photoreceptor activity, G-protein coupled|G-protein coupled photoreceptor activity											GO:0004975		molecular_function											owl:Class	
GO:0009584	biolink:NamedThing	detection of visible light	The series of events in which a visible light stimulus is received by a cell and converted into a molecular signal. A visible light stimulus is electromagnetic radiation that can be perceived visually by an organism; for organisms lacking a visual system, this can be defined as light with a wavelength within the range 380 to 780 nm.	tmpzr1t_l9r_go_relaxed.owl	perception of visible light													biological_process											owl:Class	
GO:0045494	biolink:NamedThing	photoreceptor cell maintenance	Any process preventing the degeneration of the photoreceptor, a specialized cell type that is sensitive to light.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0001895	biolink:NamedThing	retina homeostasis	A tissue homeostatic process involved in the maintenance of an internal equilibrium within the retina of the eye, including control of cellular proliferation and death and control of metabolic function.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0043306	biolink:NamedThing	positive regulation of mast cell degranulation	Any process that activates or increases the frequency, rate or extent of mast cell degranulation.	tmpzr1t_l9r_go_relaxed.owl	upregulation of mast cell degranulation|up regulation of mast cell degranulation|positive regulation of mast cell granule exocytosis|activation of mast cell degranulation|stimulation of mast cell degranulation|up-regulation of mast cell degranulation													biological_process											owl:Class	
GO:0043303	biolink:NamedThing	mast cell degranulation	The regulated exocytosis of secretory granules containing preformed mediators such as histamine, serotonin, and neutral proteases by a mast cell.	tmpzr1t_l9r_go_relaxed.owl	mast cell granule exocytosis	https://github.com/geneontology/go-ontology/issues/15943												biological_process											owl:Class	
GO:0120293	biolink:NamedThing	dynein axonemal particle	An aggregation of axonemal dyneins, their specific assembly factors, and broadly-acting chaperones that is located in the cytoplasm.	tmpzr1t_l9r_go_relaxed.owl	DynAP	https://github.com/geneontology/go-ontology/issues/20687						krc	2021-01-19T01:47:17Z					cellular_component											owl:Class	
GO:0072117	biolink:NamedThing	head kidney formation	The developmental process pertaining to the initial formation of the head kidney. The head kidney is a pronephros that consists of fused bilateral lobes located in the anterior part of the kidney.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-02-22T11:17:20Z					biological_process											owl:Class	
GO:0048144	biolink:NamedThing	fibroblast proliferation	The multiplication or reproduction of fibroblast cells, resulting in the expansion of the fibroblast population.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0070517	biolink:NamedThing	DNA replication factor C core complex	A protein complex containing three of the five subunits of eukaryotic replication factor C, those corresponding to human p40, p38, and p37.	tmpzr1t_l9r_go_relaxed.owl	RFC core complex													cellular_component											owl:Class	
GO:0106061	biolink:NamedThing	negative regulation of exit from meiosis	Any process that stops, prevents or reduces the frequency, rate or extent of exit from meiosis.	tmpzr1t_l9r_go_relaxed.owl								hjd	2017-10-18T16:51:15Z					biological_process											owl:Class	
GO:1990947	biolink:NamedThing	exit from meiosis	Any process involved in the progression from anaphase/telophase of meiosis II to the creation of end products of meiosis, in which ploidy is reduced by half.	tmpzr1t_l9r_go_relaxed.owl	meiotic exit							vw	2016-04-21T14:14:15Z					biological_process											owl:Class	
GO:0099606	biolink:NamedThing	microtubule plus-end directed mitotic chromosome migration	The cell cycle process in which chromosomes that are laterally attached to one or more mitotic spindle microtubules migrate towards the spindle equator via plus-end-directed movement along the microtubules. This process is part of mitotic metaphase plate congression.	tmpzr1t_l9r_go_relaxed.owl	plus-end directed chromosome gliding													biological_process											owl:Class	
GO:0007080	biolink:NamedThing	mitotic metaphase plate congression	The cell cycle process in which chromosomes are aligned at the metaphase plate, a plane halfway between the poles of the mitotic spindle, during mitosis.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:2000878	biolink:NamedThing	positive regulation of oligopeptide transport	Any process that activates or increases the frequency, rate or extent of oligopeptide transport.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-07-27T01:54:11Z					biological_process											owl:Class	
GO:0006857	biolink:NamedThing	oligopeptide transport	The directed movement of oligopeptides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Oligopeptides are molecules that contain a small number (2 to 20) of amino-acid residues connected by peptide linkages.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0021780	biolink:NamedThing	glial cell fate specification	The process in which a cell becomes capable of differentiating autonomously into a glial cell in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0021781	biolink:NamedThing	glial cell fate commitment	The process in which the developmental fate of a cell becomes restricted such that it will develop into a glial cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0061850	biolink:NamedThing	growth cone leading edge	That part of the growth cone which represents the distal part of the structure.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0035471	biolink:NamedThing	luteinizing hormone signaling pathway involved in ovarian follicle development	The series of molecular signals initiated by luteinizing hormone binding to a receptor, where the activated receptor signals via downstream effectors that contribute to progression of the ovarian follicle over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl	luteinizing hormone signalling pathway involved in ovarian follicle development							bf	2010-04-22T04:43:20Z					biological_process											owl:Class	
GO:0031985	biolink:NamedThing	Golgi cisterna	Any of the thin, flattened membrane-bounded compartments that form the central portion of the Golgi complex.	tmpzr1t_l9r_go_relaxed.owl	Golgi lamellae				NIF_Subcellular:sao561419532									cellular_component											owl:Class	
GO:0005795	biolink:NamedThing	Golgi stack	The set of thin, flattened membrane-bounded compartments, called cisternae, that form the central portion of the Golgi complex. The stack usually comprises cis, medial, and trans cisternae; the cis- and trans-Golgi networks are not considered part of the stack.	tmpzr1t_l9r_go_relaxed.owl	dictyosome|Golgi cisternae											GO:0016940		cellular_component											owl:Class	
GO:0061882	biolink:NamedThing	negative regulation of anterograde axonal transport of mitochondrion	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of mitochondria along microtubules in axons away from the cell body and towards the presynapse.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of anterograde axon transport of mitochondria							dph	2017-05-30T14:25:16Z					biological_process											owl:Class	
GO:0098957	biolink:NamedThing	anterograde axonal transport of mitochondrion	The directed movement of mitochondria along microtubules in axons away from the cell body and towards the presynapse.	tmpzr1t_l9r_go_relaxed.owl	anterograde axon transport of mitochondria													biological_process											owl:Class	
GO:0043797	biolink:NamedThing	glyceraldehyde-3-phosphate dehydrogenase (ferredoxin) activity	Catalysis of the reaction: D-glyceraldehyde-3-phosphate + H2O + 2 oxidized ferredoxin = 3-phospho-D-glycerate + 2 H+ + 2 reduced ferredoxin.	tmpzr1t_l9r_go_relaxed.owl	glyceraldehyde-3-phosphate Fd oxidoreductase activity|GAPOR|glyceraldehyde-3-phosphate ferredoxin reductase activity|D-glyceraldehyde-3-phosphate:ferredoxin oxidoreductase activity				MetaCyc:1.2.7.6-RXN|RHEA:24148|EC:1.2.7.6									molecular_function											owl:Class	
GO:0046802	biolink:NamedThing	exit of virus from host cell nucleus by nuclear egress	The directed movement of an assembled viral particle out of the host cell nucleus by budding and fusion through the nuclear membranes. In this process, enveloped viral particles are formed by budding through the inner nuclear membrane. These perinuclear enveloped particles then fuse with the outer nuclear membrane to deliver a naked capsid into the host cytoplasm.	tmpzr1t_l9r_go_relaxed.owl	egress of viral procapsid from host cell nucleus|nuclear egress|nuclear egress of viral procapsid|capsid egress				VZ:1952							GO:0039676		biological_process											owl:Class	
GO:0045999	biolink:NamedThing	negative regulation of ecdysteroid secretion	Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of ecdysteroid.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of ecdysteroid secretion|downregulation of ecdysteroid secretion|inhibition of ecdysteroid secretion|down regulation of ecdysteroid secretion													biological_process											owl:Class	
GO:0045457	biolink:NamedThing	ecdysteroid secretion	The regulated release of ecdysteroids, a group of polyhydroxylated ketosteroids which initiate post-embryonic development.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0015897	biolink:NamedThing	organomercurial transport	The process in which an organomercurial compound is transported across a membrane. Organomercurial substances are any organic compound containing a mercury atom.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0061683	biolink:NamedThing	branching involved in seminal vesicle morphogenesis	The process in which the branching structure of the seminal vesicle is generated and organized. A branch is a division or offshoot from a main stem.	tmpzr1t_l9r_go_relaxed.owl	seminal vesicle branching|seminal vesicle branching morphogenesis|gonecyst branching morphogenesis|seminal gland branching morphogenesis							dph	2015-03-04T13:39:47Z					biological_process											owl:Class	
GO:0043927	biolink:NamedThing	exonucleolytic nuclear-transcribed mRNA catabolic process involved in endonucleolytic cleavage-dependent decay	The chemical reactions and pathways resulting in the breakdown of the transcript body of a nuclear-transcribed mRNA that occurs when the ends are not protected by the 5'-cap.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0000294	biolink:NamedThing	nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay	A minor degradation pathway nuclear-transcribed mRNAs that begins with an endonucleolytic cleavage to generate unprotected ends.	tmpzr1t_l9r_go_relaxed.owl	mRNA degradation, endonucleolytic cleavage-dependent decay|endonucleolytic mRNA decay|nuclear mRNA catabolic process, endonucleolytic cleavage-dependent decay|mRNA breakdown, endonucleolytic cleavage-dependent decay|mRNA catabolism, endonucleolytic|mRNA catabolic process, endonucleolytic													biological_process											owl:Class	
GO:1902677	biolink:NamedThing	left caudal basal body	Any ciliary basal body that is part of a left caudal flagellum found in Giardia species (trophozoite stage).	tmpzr1t_l9r_go_relaxed.owl	cilium basal body of left caudal flagellum|microtubule basal body of left caudal flagellum|cilial basal body of left caudal flagellum|ciliary basal body of left caudal cilium|ciliary basal body of left caudal flagellum|cilial basal body of left caudal cilium|left caudal flagellum ciliary basal body|cilium basal body of left caudal cilium|microtubule basal body of left caudal cilium					Note that we deem cilium and microtubule-based flagellum to be equivalent. Also note that, due to the asymmetric nature of the Giardia trophozoite, this term is defined spatially as the trophozoite is viewed from the dorsal side, with the two nuclei dorsal to the ventral disc, and the ventral disc toward the anterior.		pr	2014-02-05T15:00:36Z					cellular_component											owl:Class	
GO:0097560	biolink:NamedThing	left caudal flagellum	A cilium (also called flagellum) found in Giardia species (trophozoite stage). It is nucleated by the left caudal basal body, extending cytoplasmically and exiting at the posterior end of the cell body.	tmpzr1t_l9r_go_relaxed.owl	left caudal cilium					Note that we deem cilium and microtubule-based flagellum to be equivalent; the primary term name reflects frequency of use. Also note that, due to the asymmetric nature of the Giardia trophozoite, this term is defined spatially as the trophozoite is viewed from the dorsal side, with the two nuclei dorsal to the ventral disc, and the ventral disc toward the anterior.		pr	2014-02-05T13:29:44Z					cellular_component											owl:Class	
GO:0035922	biolink:NamedThing	foramen ovale closure	The morphogenetic process in which the foramen ovale closes after birth, to prevent blood flow between the right and left atria. In the fetal heart, the foramen ovale allows blood to enter the left atrium from the right atrium. Closure of the foramen ovale after birth stops this blood flow.	tmpzr1t_l9r_go_relaxed.owl	foramen ovale of heart closure							bf	2011-07-05T01:39:54Z					biological_process											owl:Class	
GO:0060728	biolink:NamedThing	negative regulation of coreceptor activity involved in epidermal growth factor receptor signaling pathway	Any process that decreases the rate or frequency of coreceptor activity involved in epidermal growth factor receptor signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of Neu/ErbB-2 receptor activity|negative regulation of coreceptor activity involved in epidermal growth factor receptor signalling pathway							dph	2009-06-12T01:32:38Z					biological_process											owl:Class	
GO:0060724	biolink:NamedThing	coreceptor activity involved in epidermal growth factor receptor signaling pathway	Combining with an extracellular messenger, and in cooperation with a primary EGF receptor, initiating a change in cell activity through the EGF receptor signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	coreceptor activity involved in epidermal growth factor receptor signalling pathway							dph	2009-06-12T01:06:08Z					molecular_function											owl:Class	
GO:1902416	biolink:NamedThing	positive regulation of mRNA binding	Any process that activates or increases the frequency, rate or extent of mRNA binding.	tmpzr1t_l9r_go_relaxed.owl	upregulation of mRNA binding|up regulation of mRNA binding|up-regulation of mRNA binding|activation of mRNA binding							rb	2013-09-13T18:57:24Z					biological_process											owl:Class	
GO:1903049	biolink:NamedThing	negative regulation of acetylcholine-gated cation channel activity	Any process that stops, prevents or reduces the frequency, rate or extent of acetylcholine-gated cation channel activity.	tmpzr1t_l9r_go_relaxed.owl	inhibition of acetylcholine-gated cation channel activity|down-regulation of acetylcholine-gated cation channel activity|downregulation of acetylcholine-gated cation channel activity|down regulation of acetylcholine-gated cation channel activity							bf	2014-05-22T14:47:00Z					biological_process											owl:Class	
GO:0022848	biolink:NamedThing	acetylcholine-gated cation-selective channel activity	Selectively enables the transmembrane transfer of a cation by a channel that opens upon binding acetylcholine.	tmpzr1t_l9r_go_relaxed.owl	acetylcholine-activated cation-selective channel activity|nicotinic acetylcholine-activated cation-selective channel activity|nAChR|nicotinergic acetylcholine receptor activity|ionotropic acetylcholine receptor activity|acetylcholine-gated cation channel activity											GO:0016904|GO:0004889		molecular_function											owl:Class	
GO:0070923	biolink:NamedThing	siRNA loading onto RISC involved in gene silencing by small RNA	The process in which a single-stranded small RNA associates with the RNA-initiated silencing complex (RISC); occurs as part of a process of chromatin gene by small RNA.	tmpzr1t_l9r_go_relaxed.owl	chromatin silencing by small RNA, siRNA loading onto RISC|siRNA loading onto RISC involved in chromatin silencing by small RNA	https://github.com/geneontology/go-ontology/issues/22058						mah	2009-09-11T04:01:44Z					biological_process											owl:Class	
GO:0031048	biolink:NamedThing	heterochromatin assembly by small RNA	Assembly of heterochromatin, directed by small RNAs sharing sequence identity to the repressed region.	tmpzr1t_l9r_go_relaxed.owl	RNA-mediated transcriptional silencing|small RNA-mediated heterochromatin formation|heterochromatin formation involved in chromatin silencing by small RNA|RNA-mediated chromatin silencing|small RNA-mediated heterochromatic silencing|chromatin silencing by small RNA|RNA interference-like chromatin silencing|RNA-mediated TGS|RNAi-like chromatin silencing|RNAi-directed chromatin silencing|heterochromatin assembly involved in chromatin silencing by small RNA							mah	2009-09-11T04:10:51Z			GO:0070924		biological_process											owl:Class	
GO:0072377	biolink:NamedThing	blood coagulation, common pathway	A protein activation cascade that contributes to blood coagulation and consists of events leading from the formation of activated factor X to the formation of active thrombin, the cleavage of fibrinogen by thrombin, and the formation of cleaved fibrin into a stable multimeric, cross-linked complex.	tmpzr1t_l9r_go_relaxed.owl						See also the biological process term 'blood coagulation, intrinsic pathway ; GO:0007597'.		mah	2010-11-22T03:01:12Z					biological_process											owl:Class	
GO:0060993	biolink:NamedThing	kidney morphogenesis	Morphogenesis of a kidney. A kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-01-19T08:16:55Z					biological_process											owl:Class	
GO:0072034	biolink:NamedThing	renal vesicle induction	Signaling at short range between cells of the ureteric bud terminus and the kidney mesenchyme that positively regulates the formation of the renal vesicle.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of nephron formation|nephron induction							mah	2010-01-25T02:58:18Z					biological_process											owl:Class	
GO:1905648	biolink:NamedThing	regulation of shell calcification	Any process that modulates the frequency, rate or extent of shell calcification.	tmpzr1t_l9r_go_relaxed.owl								pga	2016-11-08T16:24:36Z					biological_process											owl:Class	
GO:0031215	biolink:NamedThing	shell calcification	The precipitation of calcium carbonate onto the organic matrix of a shell, such as a mollusc shell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1990399	biolink:NamedThing	epithelium regeneration	The regrowth of lost or destroyed epithelium.	tmpzr1t_l9r_go_relaxed.owl	regeneration of epithelium							sl	2014-06-12T17:14:42Z					biological_process											owl:Class	
GO:1901706	biolink:NamedThing	mesenchymal cell differentiation involved in bone development	The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesenchymal cells of bone as it progresses from its formation to the mature state.	tmpzr1t_l9r_go_relaxed.owl								hjd	2012-12-14T16:04:16Z					biological_process											owl:Class	
GO:0010937	biolink:NamedThing	regulation of cytoplasmic microtubule depolymerization	Any process that modulates the frequency, rate or extent of cytoplasmic microtubule depolymerization.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:2000349	biolink:NamedThing	negative regulation of CD40 signaling pathway	Any process that stops, prevents or reduces the frequency, rate or extent of signaling via the CD40 signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of CD40 signalling pathway							mah	2011-02-03T10:29:44Z					biological_process											owl:Class	
GO:0023035	biolink:NamedThing	CD40 signaling pathway	A series of molecular signals initiated by the binding of the cell surface receptor CD40 to one of its physiological ligands, and ending with regulation of a downstream cellular process, e.g. transcription.	tmpzr1t_l9r_go_relaxed.owl	CD40 signalling pathway								2010-02-16T09:30:50Z					biological_process											owl:Class	
GO:0033503	biolink:NamedThing	HULC complex	A ubiquitin-conjugating enzyme complex that contains two RING finger proteins, which have ubiquitin ligase activity, in addition to a protein with ubiquitin-conjugating enzyme activity; catalyzes the ubiquitination of histone H2B at lysine 119 (or the equivalent residue). In Schizosaccharomyces the subunits are Rhp1, Brl2/Rfp1 and Brl1/Rfp2.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/22142												cellular_component											owl:Class	
GO:1904765	biolink:NamedThing	positive regulation of transcription from RNA polymerase II promoter in response to maltose	Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a maltose stimulus.	tmpzr1t_l9r_go_relaxed.owl	up regulation of transcription from RNA polymerase II promoter involved in cellular response to maltose stimulus|stimulation of global transcription from RNA polymerase II promoter involved in cellular response to maltose stimulus|positive regulation of gene-specific transcription from RNA polymerase II promoter involved in cellular response to maltose stimulus|upregulation of transcription from RNA polymerase II promoter involved in cellular response to maltose stimulus|upregulation of global transcription from RNA polymerase II promoter involved in cellular response to maltose stimulus|positive regulation of transcription from RNA polymerase II promoter, global involved in cellular response to maltose stimulus|positive regulation of transcription from RNA polymerase II promoter involved in cellular response to maltose stimulus|positive regulation of global transcription from Pol II promoter involved in cellular response to maltose stimulus|up-regulation of global transcription from RNA polymerase II promoter involved in cellular response to maltose stimulus|positive regulation of transcription from Pol II promoter involved in cellular response to maltose stimulus|up-regulation of transcription from RNA polymerase II promoter involved in cellular response to maltose stimulus|activation of global transcription from RNA polymerase II promoter involved in cellular response to maltose stimulus|stimulation of transcription from RNA polymerase II promoter involved in cellular response to maltose stimulus|up regulation of global transcription from RNA polymerase II promoter involved in cellular response to maltose stimulus|activation of transcription from RNA polymerase II promoter involved in cellular response to maltose stimulus							mah	2015-10-26T16:42:15Z					biological_process											owl:Class	
GO:0071328	biolink:NamedThing	cellular response to maltose stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a maltose stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-12-10T05:30:45Z					biological_process											owl:Class	
GO:0072289	biolink:NamedThing	metanephric nephron tubule formation	The developmental process pertaining to the initial formation of a metanephric nephron tubule from unspecified parts. A metanephric nephron tubule is an epithelial tube that is part of a nephron in the metanephros.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-04-09T03:47:44Z					biological_process											owl:Class	
GO:0072282	biolink:NamedThing	metanephric nephron tubule morphogenesis	The process in which the anatomical structures of a metanephric nephron tubule are generated and organized. A metanephric nephron tubule is an epithelial tube that is part of the metanephric nephron, the functional part of the metanephros.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-04-01T03:25:11Z					biological_process											owl:Class	
GO:0015139	biolink:NamedThing	alpha-ketoglutarate transmembrane transporter activity	Enables the transfer of alpha-ketoglutarate from one side of a membrane to the other. Alpha-ketoglutarate (or oxoglutarate) is a compound with important roles in carbohydrate and amino acid metabolism, especially in transamination reactions and as a component of the TCA cycle.	tmpzr1t_l9r_go_relaxed.owl	2-oxoglutarate transporter activity				Reactome:R-HSA-372480									molecular_function											owl:Class	
GO:0060395	biolink:NamedThing	SMAD protein signal transduction	The cascade of processes by which a signal interacts with a receptor, causing a change in the activity of a SMAD protein, and ultimately effecting a change in the functioning of the cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0009920	biolink:NamedThing	cell plate formation involved in plant-type cell wall biogenesis	The cell cycle process in which the cell plate is formed at the equator of the spindle in the dividing cells during early telophase. An example of this is found in Arabidopsis thaliana.	tmpzr1t_l9r_go_relaxed.owl	cell plate formation involved in cellulose and pectin-containing cell wall biogenesis													biological_process											owl:Class	
GO:0061640	biolink:NamedThing	cytoskeleton-dependent cytokinesis	A cytokinesis that involves the function of a set of proteins that are part of the microfilament or microtubule cytoskeleton.	tmpzr1t_l9r_go_relaxed.owl								dph	2014-08-22T14:21:35Z					biological_process											owl:Class	
GO:0019430	biolink:NamedThing	removal of superoxide radicals	Any process, acting at the cellular level, involved in removing superoxide radicals (O2-) from a cell or organism, e.g. by conversion to dioxygen (O2) and hydrogen peroxide (H2O2).	tmpzr1t_l9r_go_relaxed.owl	cellular detoxification of superoxide radicals|removal of oxygen free radicals|removal of O2-				MetaCyc:DETOX1-PWY									biological_process											owl:Class	
GO:0005821	biolink:NamedThing	intermediate layer of spindle pole body	Structure between the central and outer plaques of the spindle pole body.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0005816	biolink:NamedThing	spindle pole body	The microtubule organizing center in fungi; functionally homologous to the animal cell centrosome.	tmpzr1t_l9r_go_relaxed.owl	SPB				Wikipedia:Spindle_pole_body									cellular_component											owl:Class	
GO:0050928	biolink:NamedThing	negative regulation of positive chemotaxis	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a motile cell or organism towards a higher concentration in a concentration gradient of a specific chemical.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of positive chemotaxis|down regulation of positive chemotaxis|downregulation of positive chemotaxis|inhibition of positive chemotaxis													biological_process											owl:Class	
GO:0002363	biolink:NamedThing	alpha-beta T cell lineage commitment	The process in which a pro-T cell becomes committed to becoming an alpha-beta T cell.	tmpzr1t_l9r_go_relaxed.owl	alpha-beta T-cell lineage commitment|alpha-beta T lymphocyte lineage commitment|alpha-beta T-lymphocyte lineage commitment													biological_process											owl:Class	
GO:0036502	biolink:NamedThing	Derlin-1-VIMP complex	A protein complex containing, in mammals, Derlin-1 and VCP-interacting membrane protein (VIMP). The complex links the p97/VCP-containing ATPase complex with Derlin-1 during translocation of protein substrates from the endoplasmic reticulum to the cytosol for degradation by the cytosolic proteasome.	tmpzr1t_l9r_go_relaxed.owl	Derlin-1/VIMP complex							bf	2015-05-14T11:40:45Z					cellular_component											owl:Class	
GO:0014853	biolink:NamedThing	regulation of excitatory postsynaptic membrane potential involved in skeletal muscle contraction	Any process, involved in skeletal muscle contraction, that modulates the establishment or extent of the excitatory postsynaptic potential (EPSP). Excitatory postsynaptic potential (EPSP) is a temporay increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC) and makes it easier for the neuron to fire an action potential.	tmpzr1t_l9r_go_relaxed.owl	regulation of excitatory post-synaptic membrane potential involved in skeletal muscle contraction													biological_process											owl:Class	
GO:0014852	biolink:NamedThing	regulation of skeletal muscle contraction by neural stimulation via neuromuscular junction	Any process that modulates the frequency, rate or extent of skeletal muscle contraction by variation of the pattern of stimulation by nervous system.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0043229	biolink:NamedThing	intracellular organelle	Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:2000488	biolink:NamedThing	positive regulation of brassinosteroid biosynthetic process	Any process that activates or increases the frequency, rate or extent of brassinosteroid biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of brassinosteroid biosynthesis|positive regulation of brassinosteroid formation|positive regulation of brassinosteroid synthesis|positive regulation of brassinosteroid anabolism							dhl	2011-03-11T06:48:45Z					biological_process											owl:Class	
GO:0016132	biolink:NamedThing	brassinosteroid biosynthetic process	The chemical reactions and pathways resulting in the formation of brassinosteroids, any of a group of steroid derivatives that occur at very low concentrations in plant tissues and may have hormone-like effects.	tmpzr1t_l9r_go_relaxed.owl	brassinosteroid synthesis|brassinosteroid formation|brassinosteroid anabolism|brassinosteroid biosynthesis				MetaCyc:PWY-699|MetaCyc:PWY-2582									biological_process											owl:Class	
GO:0086073	biolink:NamedThing	bundle of His cell-Purkinje myocyte adhesion involved in cell communication	The attachment of a bundle of His cell to a Purkinje myocyte via adhesion molecules that results in the cells being juxtaposed so that they can communicate.	tmpzr1t_l9r_go_relaxed.owl								dph	2011-11-22T10:00:30Z					biological_process											owl:Class	
GO:0042010	biolink:NamedThing	interleukin-15 receptor activity	Combining with interleukin-15 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	IL-15 receptor activity|IL-15R													molecular_function											owl:Class	
GO:0039648	biolink:NamedThing	modulation by virus of host protein ubiquitination	Any process in which a virus modulates the frequency, rate or extent of protein ubiquitination in the host organism. Ubiquitination is the process in which one or more ubiquitin groups are added to a protein.	tmpzr1t_l9r_go_relaxed.owl	modulation of host ubiquitin pathway by virus							bf	2012-10-09T15:20:47Z					biological_process											owl:Class	
GO:0030424	biolink:NamedThing	axon	The long process of a neuron that conducts nerve impulses, usually away from the cell body to the terminals and varicosities, which are sites of storage and release of neurotransmitter.	tmpzr1t_l9r_go_relaxed.owl					NIF_Subcellular:sao1770195789|Wikipedia:Axon									cellular_component											owl:Class	
GO:0015145	biolink:NamedThing	monosaccharide transmembrane transporter activity	Enables the transfer of a monosaccharide from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0015749	biolink:NamedThing	monosaccharide transmembrane transport	The process in which a monosaccharide is transported across a lipid bilayer, from one side of a membrane to the other. Monosaccharides are the simplest carbohydrates; they are polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms. They form the constitutional repeating units of oligo- and polysaccharides.	tmpzr1t_l9r_go_relaxed.owl	monosaccharide transport							vw	2017-02-19T10:41:27Z			GO:1905950		biological_process											owl:Class	
GO:0009758	biolink:NamedThing	carbohydrate utilization	A series of processes that forms an integrated mechanism by which a cell or an organism detects the depletion of primary carbohydrate sources,usually glucose, and then activates genes to scavenge the last traces of the primary carbohydrate source and to transport and metabolize alternate carbohydrate sources. The utilization process begins when the cell or organism detects carbohydrate levels, includes the activation of genes whose products detect, transport or metabolize carbohydrates, and ends when the carbohydrate is incorporated into the cell or organism's metabolism.	tmpzr1t_l9r_go_relaxed.owl	sugar utilization											GO:0007587		biological_process											owl:Class	
GO:0009730	biolink:NamedThing	detection of carbohydrate stimulus	The series of events in which a carbohydrate stimulus is received by a cell and converted into a molecular signal.	tmpzr1t_l9r_go_relaxed.owl	perception of carbohydrate stimulus													biological_process											owl:Class	
GO:0035852	biolink:NamedThing	horizontal cell localization	Any process in which a horizontal cell is transported to, and/or maintained in, a specific location within the inner nuclear layer (INL) of the retina. A horizontal cell is a neuron that laterally connects other neurons in the inner nuclear layer (INL) of the retina. Targeting of retinal neurons to the appropriate lamina is vital to establish the architecture of the retina.	tmpzr1t_l9r_go_relaxed.owl	horizontal cell positioning|retinal horizontal cell positioning|laminar positioning of retinal horizontal cell|horizontal cell localisation							bf	2011-05-11T01:56:40Z					biological_process											owl:Class	
GO:0046868	biolink:NamedThing	mesosome	An intracellular, often complex, membranous structure, sometimes with additional membranous lamellae inside, found in bacteria. They are associated with synthesis of DNA and secretion of proteins.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Mesosome									cellular_component											owl:Class	
GO:0070588	biolink:NamedThing	calcium ion transmembrane transport	A process in which a calcium ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	transmembrane calcium transport|calcium ion membrane transport					Note that this term is not intended for use in annotating lateral movement within membranes.		mah	2009-04-28T10:44:09Z					biological_process											owl:Class	
GO:1904830	biolink:NamedThing	negative regulation of aortic smooth muscle cell differentiation	Any process that stops, prevents or reduces the frequency, rate or extent of aortic smooth muscle cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	down regulation of aortic smooth muscle cell differentiation|downregulation of aortic smooth muscle cell differentiation|inhibition of aortic smooth muscle cell differentiation|down-regulation of aortic smooth muscle cell differentiation							rph	2015-11-24T10:20:47Z					biological_process											owl:Class	
GO:0035887	biolink:NamedThing	aortic smooth muscle cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell surrounding the aorta.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-06-08T11:34:26Z					biological_process											owl:Class	
GO:2001282	biolink:NamedThing	negative regulation of muscle cell chemotaxis toward tendon cell	Any process that stops, prevents or reduces the frequency, rate or extent of the directed movement of a muscle cell towards a tendon cell in response to an external stimulus. For example, when the muscle cell arrives at the target tendon cell, migration is arrested so that attachments can be made between the cells.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of muscle cell attraction|negative regulation of muscle cell chemotaxis towards tendon cell|arrest of muscle cell chemotaxis							bf	2011-12-15T10:39:42Z					biological_process											owl:Class	
GO:0036061	biolink:NamedThing	muscle cell chemotaxis toward tendon cell	The directed movement of a muscle cell towards a tendon cell in response to an external stimulus. Tendon cells, for example, produce positive guidance cues that attract muscle cells.	tmpzr1t_l9r_go_relaxed.owl	muscle cell attraction|muscle cell chemotaxis towards tendon cell							bf	2011-12-14T11:13:40Z					biological_process											owl:Class	
GO:0044330	biolink:NamedThing	canonical Wnt signaling pathway involved in positive regulation of wound healing	The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes involved in positive regulation of wound healing.	tmpzr1t_l9r_go_relaxed.owl	canonical Wnt receptor signaling pathway involved in positive regulation of wound healing|canonical Wnt-activated signaling pathway involved in positive regulation of wound healing|canonical Wnt receptor signalling pathway involved in positive regulation of wound healing							jl	2010-08-18T04:21:21Z					biological_process											owl:Class	
GO:0090303	biolink:NamedThing	positive regulation of wound healing	Any process that increases the rate, frequency, or extent of the series of events that restore integrity to a damaged tissue, following an injury.	tmpzr1t_l9r_go_relaxed.owl								tb	2010-03-22T02:12:03Z					biological_process											owl:Class	
GO:0046974	biolink:NamedThing	histone methyltransferase activity (H3-K9 specific)	Catalysis of the reaction: S-adenosyl-L-methionine + histone H3 L-lysine (position 9) = S-adenosyl-L-homocysteine + histone H3 N6-methyl-L-lysine (position 9). This reaction is the addition of a methyl group onto lysine at position 9 of the histone H3 protein.	tmpzr1t_l9r_go_relaxed.owl	histone lysine N-methyltransferase activity (H3-K9 specific)|histone methylase activity (H3-K9 specific)				Reactome:R-HSA-427527|Reactome:R-HSA-427336									molecular_function											owl:Class	
GO:0062026	biolink:NamedThing	negative regulation of SCF-dependent proteasomal ubiquitin-dependent catabolic process	Any process that stops or decreases the rate, frequency or extent of SCF-dependent proteasomal ubiquitin-dependent protein catabolic process, the chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, with ubiquitin-protein ligation catalyzed by an SCF (Skp1/Cul1/F-box protein) complex, and mediated by the proteasome.	tmpzr1t_l9r_go_relaxed.owl								dph	2018-04-16T14:02:20Z					biological_process											owl:Class	
GO:0031146	biolink:NamedThing	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, with ubiquitin-protein ligation catalyzed by an SCF (Skp1/Cul1/F-box protein) complex, and mediated by the proteasome.	tmpzr1t_l9r_go_relaxed.owl	SCF-dependent proteasomal ubiquitin-dependent protein catabolism|SCF-dependent proteasomal ubiquitin-dependent protein degradation|SCF-dependent proteasomal ubiquitin-dependent protein breakdown													biological_process											owl:Class	
GO:0120194	biolink:NamedThing	regulation of anther dehiscence	Any process involved in the dehiscence of an anther to release the pollen grains contained within it.	tmpzr1t_l9r_go_relaxed.owl								krc	2019-04-09T21:40:39Z					biological_process											owl:Class	
GO:0009901	biolink:NamedThing	anther dehiscence	The dehiscence of an anther to release the pollen grains contained within it.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1901895	biolink:NamedThing	negative regulation of ATPase-coupled calcium transmembrane transporter activity	Any process that stops, prevents or reduces the frequency, rate or extent of an  ATPase-coupled calcium transmembrane transporter activity.	tmpzr1t_l9r_go_relaxed.owl	downregulation of calcium efflux ATPase|down-regulation of calcium transporting ATPase activity|negative regulation of calcium ABC transporter|inhibition of calcium efflux ATPase|inhibition of sarcoplasmic reticulum ATPase|down regulation of Ca2+-transporting ATPase activity|down regulation of sarcoplasmic reticulum ATPase|downregulation of sarcoplasmic reticulum ATPase|negative regulation of sarcoplasmic reticulum ATPase|inhibition of calcium pump|down-regulation of Ca2+-pumping ATPase activity|negative regulation of calcium-translocating P-type ATPase activity|negative regulation of Ca(2+)-transporting ATPase activity|inhibition of Ca2+-transporting ATPase activity|negative regulation of calcium efflux ATPase|inhibition of ATP phosphohydrolase (Ca2+-transporting)|down-regulation of Ca(2+)-transporting ATPase activity|downregulation of plasma membrane Ca-ATPase|negative regulation of sarco(endo)plasmic reticulum Ca2+-ATPase|inhibition of calcium-transporting ATPase activity|downregulation of calcium-transporting ATPase activity|down-regulation of calcium-translocating P-type ATPase activity|downregulation of calcium ABC transporter|down regulation of calcium ABC transporter|inhibition of plasma membrane Ca-ATPase|down-regulation of calcium-transporting ATPase activity|negative regulation of ATP phosphohydrolase (Ca2+-transporting)|downregulation of Ca(2+)-transporting ATPase activity|inhibition of Ca2+-pumping ATPase activity|down regulation of calcium transporting ATPase activity|negative regulation of plasma membrane Ca-ATPase|negative regulation of calcium pump|downregulation of Ca2+-pumping ATPase activity|down regulation of Ca(2+)-transporting ATPase activity|down-regulation of Ca2+-transporting ATPase activity|down regulation of calcium-translocating P-type ATPase activity|inhibition of calcium-translocating P-type ATPase activity|down regulation of ATP phosphohydrolase (Ca2+-transporting)|inhibition of calcium ABC transporter|down regulation of calcium-transporting ATPase activity|downregulation of ATP phosphohydrolase (Ca2+-transporting)|down-regulation of calcium efflux ATPase|negative regulation of Ca2+-transporting ATPase activity|down regulation of calcium efflux ATPase|negative regulation of Ca2+-pumping ATPase activity|downregulation of calcium-translocating P-type ATPase activity|negative regulation of calcium transporting ATPase activity|down regulation of plasma membrane Ca-ATPase|inhibition of Ca(2+)-transporting ATPase activity|down-regulation of sarco(endo)plasmic reticulum Ca2+-ATPase|down-regulation of calcium ABC transporter|down regulation of calcium pump|down regulation of sarco(endo)plasmic reticulum Ca2+-ATPase|down-regulation of plasma membrane Ca-ATPase|down-regulation of calcium pump|negative regulation of calcium-transporting ATPase activity|downregulation of Ca2+-transporting ATPase activity|down-regulation of sarcoplasmic reticulum ATPase|downregulation of sarco(endo)plasmic reticulum Ca2+-ATPase|down-regulation of ATP phosphohydrolase (Ca2+-transporting)|inhibition of sarco(endo)plasmic reticulum Ca2+-ATPase|down regulation of Ca2+-pumping ATPase activity|downregulation of calcium pump|inhibition of calcium transporting ATPase activity|downregulation of calcium transporting ATPase activity							rl	2013-02-06T21:18:25Z					biological_process											owl:Class	
GO:0045507	biolink:NamedThing	interleukin-25 receptor activity	Combining with interleukin-25 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	IL-25R|IL-25 receptor activity													molecular_function											owl:Class	
GO:0045511	biolink:NamedThing	interleukin-25 binding	Binding to interleukin-25.	tmpzr1t_l9r_go_relaxed.owl	IL-25 binding													molecular_function											owl:Class	
GO:0061288	biolink:NamedThing	mesonephric capsule specification	The regionalization process in which the identity of the mesonephric capsule is specified. Identity is considered to be the aggregate of characteristics by which a structure is recognized.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-09-02T01:56:20Z					biological_process											owl:Class	
GO:0030712	biolink:NamedThing	negative regulation of border follicle cell delamination	Any process that decreases the frequency, rate or extent of border cell delamination.	tmpzr1t_l9r_go_relaxed.owl	inhibition of border follicle cell delamination|downregulation of border follicle cell delamination|down regulation of border follicle cell delamination|down-regulation of border follicle cell delamination|negative regulation of border cell delamination													biological_process											owl:Class	
GO:0030709	biolink:NamedThing	border follicle cell delamination	The delamination process that results in the splitting off of border cells from the anterior epithelium, prior to border cell migration.	tmpzr1t_l9r_go_relaxed.owl	border cell delamination													biological_process											owl:Class	
GO:0098908	biolink:NamedThing	regulation of neuronal action potential	Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a neuron. This typically occurs via modulation of the activity or expression of voltage-gated ion channels.	tmpzr1t_l9r_go_relaxed.owl	generation of action potential													biological_process											owl:Class	
GO:0019228	biolink:NamedThing	neuronal action potential	An action potential that occurs in a neuron.	tmpzr1t_l9r_go_relaxed.owl	generation of action potential													biological_process											owl:Class	
GO:0048714	biolink:NamedThing	positive regulation of oligodendrocyte differentiation	Any process that activates or increases the frequency, rate or extent of oligodendrocyte differentiation.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of oligodendrocyte differentiation|upregulation of oligodendrocyte differentiation|activation of oligodendrocyte differentiation|up regulation of oligodendrocyte differentiation|stimulation of oligodendrocyte differentiation													biological_process											owl:Class	
GO:0061226	biolink:NamedThing	proximal/distal pattern formation involved in mesonephric nephron development	The regionalization process in which specific areas of cell differentiation are determined along a proximal/distal axis of a nephron in the mesonephros. The proximal/distal axis is defined by a line that runs from the glomerulus (proximal end) outward toward the mesonephric duct (distal end).	tmpzr1t_l9r_go_relaxed.owl								dph	2010-08-19T02:10:25Z					biological_process											owl:Class	
GO:0005665	biolink:NamedThing	RNA polymerase II, core complex	RNA polymerase II, one of three nuclear DNA-directed RNA polymerases found in all eukaryotes, is a multisubunit complex; typically it produces mRNAs, snoRNAs, and some of the snRNAs. Two large subunits comprise the most conserved portion including the catalytic site and share similarity with other eukaryotic and bacterial multisubunit RNA polymerases. The largest subunit of RNA polymerase II contains an essential carboxyl-terminal domain (CTD) composed of a variable number of heptapeptide repeats (YSPTSPS). The remainder of the complex is composed of smaller subunits (generally ten or more), some of which are also found in RNA polymerases I and III. Although the core is competent to mediate ribonucleic acid synthesis, it requires additional factors to select the appropriate template.	tmpzr1t_l9r_go_relaxed.owl	RNAP II complex|DNA-directed RNA polymerase II, core complex|RNA polymerase II complex													cellular_component											owl:Class	
GO:1990783	biolink:NamedThing	periphagosomal region of cytoplasm	Cytoplasm situated near, or occurring around, a phagosome.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-06-23T21:46:10Z					cellular_component											owl:Class	
GO:0002066	biolink:NamedThing	columnar/cuboidal epithelial cell development	The process whose specific outcome is the progression of a columnar/cuboidal epithelial cell over time, from its formation to the mature structure. A columnar/cuboidal epithelial cell is a cell usually found in a two dimensional sheet with a free surface. Columnar/cuboidal epithelial cells take on the shape of a column or cube.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0002065	biolink:NamedThing	columnar/cuboidal epithelial cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a columnar/cuboidal epithelial cell. A columnar/cuboidal epithelial cell is a cell usually found in a two dimensional sheet with a free surface. Columnar/cuboidal epithelial cells take on the shape of a column or cube.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0010987	biolink:NamedThing	negative regulation of high-density lipoprotein particle clearance	Any process that decreases the rate, frequency or extent of high-density lipoprotein particle clearance. High-density lipoprotein particle clearance is the process in which a high-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-06-01T12:09:36Z					biological_process											owl:Class	
GO:0034384	biolink:NamedThing	high-density lipoprotein particle clearance	The process in which a high-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.	tmpzr1t_l9r_go_relaxed.owl	HDL clearance													biological_process											owl:Class	
GO:2000691	biolink:NamedThing	negative regulation of cardiac muscle cell myoblast differentiation	Any process that stops, prevents or reduces the frequency, rate or extent of cardiac muscle cell myoblast differentiation.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of cardiac myoblast differentiation|negative regulation of myocardial precursor cell differentiation							yaf	2011-05-25T09:08:06Z					biological_process											owl:Class	
GO:0097695	biolink:NamedThing	establishment of protein-containing complex localization to telomere	The directed movement of a protein-containing macromolecular complex to a specific location in the telomeric region of a chromosome.	tmpzr1t_l9r_go_relaxed.owl	establishment of macromolecular complex localization to telomere|establishment of macromolecular complex localisation to telomere							pr	2015-12-22T09:38:13Z					biological_process											owl:Class	
GO:1904357	biolink:NamedThing	negative regulation of telomere maintenance via telomere lengthening	Any process that stops, prevents or reduces the frequency, rate or extent of telomere maintenance via telomere lengthening.	tmpzr1t_l9r_go_relaxed.owl	downregulation of telomere maintenance via telomere lengthening|inhibition of telomere maintenance via telomere lengthening|down-regulation of telomere maintenance via telomere lengthening|down regulation of telomere maintenance via telomere lengthening							nc	2015-06-12T16:53:22Z					biological_process											owl:Class	
GO:0010833	biolink:NamedThing	telomere maintenance via telomere lengthening	Any process that contributes to the maintenance of proper telomeric length and structure by affecting and monitoring the activity of telomeric proteins and lengthening the telomeric DNA.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0032189	biolink:NamedThing	maintenance of actomyosin contractile ring localization	Any process in which an actomyosin contractile ring is maintained in a location and prevented from moving elsewhere.	tmpzr1t_l9r_go_relaxed.owl	maintenance of contractile ring localization involved in cell cycle cytokinesis|maintenance of contractile ring localisation involved in cell cycle cytokinesis|maintenance of contractile ring localization involved in cytokinesis during cell cycle|cytokinetic ring anchoring													biological_process											owl:Class	
GO:0031566	biolink:NamedThing	actomyosin contractile ring maintenance	The cell cycle process in which the contractile ring is maintained in response to the cytokinesis checkpoint; that is when cytokinesis is delayed awaiting completion of nuclear division or the correct formation of cytokinetic structures. This process occurs in the context of cytokinesis that takes place as part of a cell cycle.	tmpzr1t_l9r_go_relaxed.owl	cytokinesis, contractile ring maintenance, involved in cytokinesis during cell cycle|contractile ring maintenance involved in cell cycle cytokinesis													biological_process											owl:Class	
GO:2001268	biolink:NamedThing	negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway	Any process that stops, prevents or reduces the frequency, rate or extent of cysteine-type endopeptidase activity involved in apoptotic signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of initiator caspase activity|negative regulation of cysteine-type endopeptidase activity involved in apoptotic signalling pathway							pr	2011-12-13T07:56:21Z					biological_process											owl:Class	
GO:0042876	biolink:NamedThing	aldarate transmembrane transporter activity	Enables the transfer of aldarate from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0042869	biolink:NamedThing	aldarate transmembrane transport	The process in which aldarate is transported across a lipid bilayer, from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	aldarate transport													biological_process											owl:Class	
GO:0022400	biolink:NamedThing	regulation of rhodopsin mediated signaling pathway	Any process that modulates the frequency, rate or extent of rhodopsin-mediated signaling.	tmpzr1t_l9r_go_relaxed.owl	regulation of rhodopsin mediated signalling													biological_process											owl:Class	
GO:0033145	biolink:NamedThing	positive regulation of intracellular steroid hormone receptor signaling pathway	Any process that activates or increases the frequency, rate or extent of the activity of any intracellular steroid hormone receptor signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of steroid hormone receptor signaling pathway|positive regulation of steroid hormone receptor signalling pathway													biological_process											owl:Class	
GO:0030518	biolink:NamedThing	intracellular steroid hormone receptor signaling pathway	A series of molecular signals generated as a consequence of a intracellular steroid hormone receptor binding to one of its physiological ligands.	tmpzr1t_l9r_go_relaxed.owl	steroid hormone receptor signaling pathway|steroid hormone receptor signalling pathway													biological_process											owl:Class	
GO:0050955	biolink:NamedThing	thermoception	The series of events required for an organism to receive a temperature stimulus, convert it to a molecular signal, and recognize and characterize the signal. Thermoception in larger animals is mainly done in the skin; mammals have at least two types of sensor, for detecting heat (temperatures above body temperature) and cold (temperatures below body temperature).	tmpzr1t_l9r_go_relaxed.owl	thermoreception				Wikipedia:Thermoception									biological_process											owl:Class	
GO:0007463	biolink:NamedThing	R2/R5 cell fate commitment	The process in which the R2/R5 photoreceptors commit to their cell fate. R2 and R5 are paired photoreceptors which contribute the outer rhabdomeres.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0048054	biolink:NamedThing	R2/R5 cell differentiation	The process in which relatively unspecialized cells acquire the specialized features of R2 and R5 photoreceptors. An example of this process is found in Drosophila melanogaster.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0005462	biolink:NamedThing	UDP-N-acetylglucosamine transmembrane transporter activity	Enables the transfer of a UDP-N-acetylglucosamine from one side of a membrane to the other. N-acetylglucosamine is a substance composed of N-acetylglucosamine, a common structural unit of oligosaccharides, in glycosidic linkage with uridine diphosphate.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-741450|Reactome:R-HSA-742354|Reactome:R-HSA-5653622									molecular_function											owl:Class	
GO:0061622	biolink:NamedThing	glycolytic process through glucose-1-phosphate	The chemical reactions and pathways through a glucose-1-phosphate intermediate that result in the catabolism of a carbohydrate into pyruvate, with the concomitant production of a small amount of ATP.	tmpzr1t_l9r_go_relaxed.owl								dph	2014-04-28T08:08:01Z					biological_process											owl:Class	
GO:0004614	biolink:NamedThing	phosphoglucomutase activity	Catalysis of the reaction: alpha-D-glucose 1-phosphate = alpha-D-glucose 6-phosphate.	tmpzr1t_l9r_go_relaxed.owl	alpha-D-glucose 1,6-phosphomutase activity|glucose phosphomutase activity|phosphoglucose mutase activity				RHEA:23536|Reactome:R-HSA-9638127|Reactome:R-HSA-70427|Reactome:R-HSA-9638125|MetaCyc:PHOSPHOGLUCMUT-RXN|Reactome:R-HSA-5609939|EC:5.4.2.2|Reactome:R-HSA-70272									molecular_function											owl:Class	
GO:0010642	biolink:NamedThing	negative regulation of platelet-derived growth factor receptor signaling pathway	Any process that stops, prevents, or reduces the frequency, rate or extent of the platelet-derived growth factor receptor signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of platelet-derived growth factor receptor signalling pathway													biological_process											owl:Class	
GO:0048008	biolink:NamedThing	platelet-derived growth factor receptor signaling pathway	The series of molecular signals generated as a consequence of a platelet-derived growth factor receptor binding to one of its physiological ligands.	tmpzr1t_l9r_go_relaxed.owl	PDGFR signaling pathway|PDGF receptor signalling pathway|PDGF receptor signaling pathway													biological_process											owl:Class	
GO:1903324	biolink:NamedThing	negative regulation of snoRNA metabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of snoRNA metabolic process.	tmpzr1t_l9r_go_relaxed.owl	down regulation of snoRNA metabolism|downregulation of snoRNA metabolism|negative regulation of snoRNA metabolism|down-regulation of snoRNA metabolic process|downregulation of snoRNA metabolic process|inhibition of snoRNA metabolic process|down regulation of snoRNA metabolic process|down-regulation of snoRNA metabolism|inhibition of snoRNA metabolism							vw	2014-08-18T13:05:25Z					biological_process											owl:Class	
GO:0016074	biolink:NamedThing	sno(s)RNA metabolic process	The chemical reactions and pathways involving snoRNA, small nucleolar RNA, any of a class of small RNAs that are associated with the eukaryotic nucleus as components of small nucleolar ribonucleoproteins. They participate in the processing or modifications of many RNAs, mostly ribosomal RNAs (rRNAs) though snoRNAs are also known to target other classes of RNA, including spliceosomal RNAs, tRNAs, and mRNAs via a stretch of sequence that is complementary to a sequence in the targeted RNA.	tmpzr1t_l9r_go_relaxed.owl	box C/D sRNA metabolic process|snoRNA metabolism													biological_process											owl:Class	
GO:0021768	biolink:NamedThing	nucleus accumbens development	The progression of the nucleus accumbens over time from its initial formation until its mature state. The nucleus accumbens is a collection of pleomorphic cells in the caudal part of the anterior horn of the lateral ventricle, in the region of the olfactory tubercle, lying between the head of the caudate nucleus and the anterior perforated substance. It is part of the ventral striatum, a composite structure considered part of the basal ganglia.	tmpzr1t_l9r_go_relaxed.owl	ventral striatum development|accumbens nucleus development													biological_process											owl:Class	
GO:0045708	biolink:NamedThing	regulation of larval salivary gland boundary specification	Any process that modulates the frequency, rate or extent of salivary gland determination in a larval organism.	tmpzr1t_l9r_go_relaxed.owl	regulation of larval salivary gland determination													biological_process											owl:Class	
GO:0007433	biolink:NamedThing	larval salivary gland boundary specification	Determination in a larval organism of where the salivary gland forms, the total number of salivary gland cells and how many cells are allocated to each of the specialised cell types within the salivary gland.	tmpzr1t_l9r_go_relaxed.owl	larval salivary gland determination													biological_process											owl:Class	
GO:0007194	biolink:NamedThing	negative regulation of adenylate cyclase activity	Any process that stops, prevents, or reduces the frequency, rate or extent of adenylate cyclase activity.	tmpzr1t_l9r_go_relaxed.owl	inhibition of adenylate cyclase activity|adenylate cyclase inhibitor|downregulation of adenylate cyclase activity|down regulation of adenylate cyclase activity|down-regulation of adenylate cyclase activity|negative regulation of adenylyl cyclase activity													biological_process											owl:Class	
GO:0001946	biolink:NamedThing	lymphangiogenesis	Lymph vessel formation when new vessels emerge from the proliferation of pre-existing vessels.	tmpzr1t_l9r_go_relaxed.owl	lymph vessel formation				Wikipedia:Lymphangiogenesis									biological_process											owl:Class	
GO:0036303	biolink:NamedThing	lymph vessel morphogenesis	The process in which the anatomical structures of lymph vessels are generated and organized. The lymph vessel is the vasculature carrying lymph.	tmpzr1t_l9r_go_relaxed.owl								bf	2012-08-08T10:08:47Z					biological_process											owl:Class	
GO:0045448	biolink:NamedThing	mitotic cell cycle, embryonic	The eukaryotic cell cycle in which a cell is duplicated without changing ploidy, occurring in the embryo.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0031520	biolink:NamedThing	plasma membrane of cell tip	The portion of the plasma membrane surrounding the cell tip.	tmpzr1t_l9r_go_relaxed.owl	'plasma membrane, cell tip'													cellular_component											owl:Class	
GO:0061283	biolink:NamedThing	specification of mesonephric distal tubule identity	The process in which the distal tubule of the mesonephric nephron acquires its identity.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-09-02T01:42:10Z					biological_process											owl:Class	
GO:0032222	biolink:NamedThing	regulation of synaptic transmission, cholinergic	Any process that modulates the frequency, rate or extent of cholinergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter acetylcholine.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0007271	biolink:NamedThing	synaptic transmission, cholinergic	The vesicular release of acetylcholine from a presynapse, across a chemical synapse, the subsequent activation of dopamine receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse.	tmpzr1t_l9r_go_relaxed.owl	cholinergic synaptic transmission													biological_process											owl:Class	
GO:1900298	biolink:NamedThing	negative regulation of hexasaccharide transport	Any process that stops, prevents or reduces the frequency, rate or extent of hexasaccharide transport.	tmpzr1t_l9r_go_relaxed.owl	downregulation of hexasaccharide transport|down-regulation of hexasaccharide transport|inhibition of hexasaccharide transport|down regulation of hexasaccharide transport							tt	2012-04-05T07:44:40Z					biological_process											owl:Class	
GO:0001056	biolink:NamedThing	RNA polymerase III activity	Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template that contains an RNA polymerase III specific promoter to direct initiation and catalyses DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'.	tmpzr1t_l9r_go_relaxed.owl	DNA-directed RNA polymerase activity involved in transcription from RNA polymerase III promoter				Reactome:R-HSA-1964482			krc	2010-09-23T03:44:47Z					molecular_function											owl:Class	
GO:0060558	biolink:NamedThing	regulation of calcidiol 1-monooxygenase activity	Any process that modulates the rate, frequency or extent of calcidiol 1-monooxygenase activity. Calcidiol 1-monooxygenase activity is catalysis of the reaction: calcidiol + NADPH + H+ + O2 = calcitriol + NADP+ + H2O.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-04-13T02:52:18Z					biological_process											owl:Class	
GO:0004498	biolink:NamedThing	calcidiol 1-monooxygenase activity	Catalysis of the reaction: calcidiol + H(+) + NADPH + O(2) = calcitriol + H(2)O + NADP(+).	tmpzr1t_l9r_go_relaxed.owl	25-hydroxycholecalciferol-1-hydroxylase activity|1-hydroxylase-25-hydroxyvitamin D3 activity|25-OHD-1 alpha-hydroxylase activity|25-hydroxyvitamin D-1 alpha hydroxylase activity|25-hydroxy D3-1alpha-hydroxylase activity|25-hydroxycholecalciferol 1-hydroxylase activity|calcidiol,NADPH:oxygen oxidoreductase (1-hydroxylating)|25-hydroxycholecalciferol 1alpha-hydroxylase activity|25-hydroxyvitamin D3 1alpha-hydroxylase activity|25-hydroxycholecalciferol 1-monooxygenase activity|cytochrome P450 CYP27B|25-hydroxy vitamin D3 1-alpha-hydroxylase activity				EC:1.14.15.18|Reactome:R-HSA-5602186|KEGG_REACTION:R03610|MetaCyc:CALCIDIOL-1-MONOOXYGENASE-RXN|Reactome:R-HSA-209868|RHEA:20573									molecular_function											owl:Class	
GO:0060123	biolink:NamedThing	regulation of growth hormone secretion	Any process that modulates the frequency, rate or extent of the regulated release of growth hormone from a cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0000465	biolink:NamedThing	exonucleolytic trimming to generate mature 5'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	Exonucleolytic digestion of a pre-rRNA molecule to generate the mature 5'-end of a 5.8S rRNA molecule derived from an originally tricistronic pre-rRNA transcript that contained the Small Subunit (SSU) rRNA, the 5.8S rRNA, and the Large Subunit (LSU) rRNA in that order from 5' to 3' along the primary transcript.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0006536	biolink:NamedThing	glutamate metabolic process	The chemical reactions and pathways involving glutamate, the anion of 2-aminopentanedioic acid.	tmpzr1t_l9r_go_relaxed.owl	glutamate metabolism|glutamic acid metabolism|glutamic acid metabolic process				Wikipedia:Glutamic_acid									biological_process											owl:Class	
GO:0048647	biolink:NamedThing	polyphenic determination	The process in which individuals that have the potential to develop any of several possible distinct developmental paths have their individual developmental fates determined in response to environmental and/or genetic cues.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0038117	biolink:NamedThing	C-C motif chemokine 19 receptor activity	Combining with the C-C motif chemokine 19 (CCL19) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	CCL19 receptor activity							bf	2012-03-22T11:59:10Z					molecular_function											owl:Class	
GO:0035757	biolink:NamedThing	chemokine (C-C motif) ligand 19 binding	Binding to chemokine (C-C motif) ligand 19.	tmpzr1t_l9r_go_relaxed.owl	CCL19 binding							bf	2011-03-25T02:02:36Z					molecular_function											owl:Class	
GO:0061908	biolink:NamedThing	phagophore	A disk-like structure that expands, rounds up into a cup-shaped structure, and eventually closes around its cargo (for example cytoplasmic components) to become an autophagosome or Cvt vesicle.	tmpzr1t_l9r_go_relaxed.owl	isolation membrane							dph	2017-06-29T16:59:19Z					cellular_component											owl:Class	
GO:0001177	biolink:NamedThing	regulation of transcription open complex formation at RNA polymerase II promoter	Any process that modulates the rate, frequency or extent of a process involved the melting of the DNA hybrid of the core promoter region within the transcriptional closed complex of an RNA polymerase II preinitiation complex (PIC) to produce an open complex where the DNA duplex around the transcription initiation site is unwound to form the transcription bubble.	tmpzr1t_l9r_go_relaxed.owl	regulation of transcriptional open complex formation at RNA polymerase II promoter							krc	2011-06-20T02:01:18Z					biological_process											owl:Class	
GO:0001113	biolink:NamedThing	transcription open complex formation at RNA polymerase II promoter	Any process involved in the melting of the DNA hybrid of the core promoter region within the transcriptional closed complex of an RNA polymerase II preinitiation complex (PIC) to produce an open complex where the DNA duplex around the transcription initiation site is unwound to form the transcription bubble.	tmpzr1t_l9r_go_relaxed.owl	transcriptional open complex formation at RNA polymerase II promoter|RNA polymerase II promoter melting							krc	2010-12-02T02:27:19Z					biological_process											owl:Class	
GO:0060127	biolink:NamedThing	prolactin secreting cell differentiation	The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a prolactin secreting cell. A prolactin secreting cell is an acidophilic cell of the anterior pituitary that produces prolactin.	tmpzr1t_l9r_go_relaxed.owl	lactotropic cell differentiation|mammotrope differentiation|mammotropic cell differentiation|lactotroph differentiation|mammotroph differentiation|mammotrophic cell differentiation|lactotrope differentiation|epsilon-acidophil differentiation													biological_process											owl:Class	
GO:0021984	biolink:NamedThing	adenohypophysis development	The progression of the adenohypophysis over time from its initial formation until its mature state. The adenohypophysis is the anterior part of the pituitary. It secretes a variety of hormones and its function is regulated by the hypothalamus.	tmpzr1t_l9r_go_relaxed.owl	anterior pituitary gland development|anterior pituitary development|adenophysis development													biological_process											owl:Class	
GO:0010935	biolink:NamedThing	regulation of macrophage cytokine production	Any process that modulates the rate, frequency or extent of macrophage cytokine production. Macrophage cytokine production is the appearance of a chemokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0010934	biolink:NamedThing	macrophage cytokine production	The appearance of a macrophage cytokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	tmpzr1t_l9r_go_relaxed.owl						Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.								biological_process											owl:Class	
GO:1902763	biolink:NamedThing	negative regulation of embryonic skeletal joint development	Any process that stops, prevents or reduces the frequency, rate or extent of embryonic skeletal joint development.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of embryonic skeletal joint development|downregulation of embryonic skeletal joint development|down regulation of embryonic skeletal joint development|inhibition of embryonic skeletal joint development							mr	2014-03-07T17:46:07Z					biological_process											owl:Class	
GO:0035043	biolink:NamedThing	male pronuclear envelope synthesis	Assembly of a nuclear envelope containing nuclear pores and a lamina around the male pronucleus, the final step in sperm pronuclear formation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0035039	biolink:NamedThing	male pronucleus assembly	The conversion at fertilization of the inactive sperm nucleus into a male pronucleus with its chromosomes processed for the first zygotic division.	tmpzr1t_l9r_go_relaxed.owl	male pronucleus formation													biological_process											owl:Class	
GO:0106134	biolink:NamedThing	positive regulation of cardiac muscle cell contraction	Any process that activates or increases the frequency, rate or extent of cardiac muscle cell contraction.	tmpzr1t_l9r_go_relaxed.owl								hjd	2018-07-26T16:05:16Z					biological_process											owl:Class	
GO:1904778	biolink:NamedThing	positive regulation of protein localization to cell cortex	Any process that activates or increases the frequency, rate or extent of protein localization to cell cortex.	tmpzr1t_l9r_go_relaxed.owl	activation of protein localisation to cell cortex|upregulation of protein localization to cell cortex|upregulation of protein localisation to cell cortex|up regulation of protein localization to cell cortex|positive regulation of protein localisation to cell cortex|up regulation of protein localisation to cell cortex|up-regulation of protein localisation to cell cortex|up-regulation of protein localization to cell cortex|activation of protein localization to cell cortex					An example is cye-1 in C. elegans, UniProt ID O01501 in PMID:17115027.		es	2015-10-29T16:55:15Z					biological_process											owl:Class	
GO:0070350	biolink:NamedThing	regulation of white fat cell proliferation	Any process that modulates the frequency, rate or extent of white fat cell proliferation.	tmpzr1t_l9r_go_relaxed.owl	regulation of white adipocyte proliferation|regulation of white adipose cell proliferation													biological_process											owl:Class	
GO:0070343	biolink:NamedThing	white fat cell proliferation	The multiplication or reproduction of white fat cells by cell division, resulting in the expansion of their population.	tmpzr1t_l9r_go_relaxed.owl	white adipose cell proliferation|white adipocyte proliferation													biological_process											owl:Class	
GO:0061037	biolink:NamedThing	negative regulation of cartilage development	Any process that decreases the rate, frequency, or extent of cartilage development, the process whose specific outcome is the progression of the cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-02-09T03:41:35Z					biological_process											owl:Class	
GO:0098023	biolink:NamedThing	virus tail, tip	The basal end of the virus tail, which is used by the virus to attach to the host cell.	tmpzr1t_l9r_go_relaxed.owl	bacteriophage tail tip							bm	2012-07-19T14:13:02Z					cellular_component											owl:Class	
GO:0098015	biolink:NamedThing	virus tail	Part of the virion that may be used to recognize, attach and inject the viral genome and accessory proteins into the host cell.	tmpzr1t_l9r_go_relaxed.owl	bacteriophage tail|viral tail					Many bacteriophages with dsDNA genomes, or Caudovirales, have a tail. The viral tail can be short (Podoviridae), long and non-contractile (Siphoviridae) or long and contractile (Myoviridae). The tail is the channel through which the phage genome is injected into the host bacterial cell.		bm	2012-07-18T17:04:46Z					cellular_component											owl:Class	
GO:0072194	biolink:NamedThing	kidney smooth muscle tissue development	The process whose specific outcome is the progression of smooth muscle in the kidney over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-03-01T02:05:30Z					biological_process											owl:Class	
GO:0021881	biolink:NamedThing	Wnt-activated signaling pathway involved in forebrain neuron fate commitment	The series of molecular signals initiated by binding of Wnt protein to a receptor on the surface of the target cell that contributes to the commitment of a neuroblast to aneuronal fate. The neuron will reside in the forebrain.	tmpzr1t_l9r_go_relaxed.owl	Wnt receptor signaling pathway involved in forebrain neuron fate commitment|Wnt receptor signalling pathway involved in forebrain neuron fate commitment													biological_process											owl:Class	
GO:0022029	biolink:NamedThing	telencephalon cell migration	The orderly movement of a cell from one site to another at least one of which is located in the telencephalon.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0021537	biolink:NamedThing	telencephalon development	The process whose specific outcome is the progression of the telencephalon over time, from its formation to the mature structure. The telencephalon is the paired anteriolateral division of the prosencephalon plus the lamina terminalis from which the olfactory lobes, cerebral cortex, and subcortical nuclei are derived.	tmpzr1t_l9r_go_relaxed.owl	cerebrum development													biological_process											owl:Class	
GO:0018344	biolink:NamedThing	protein geranylgeranylation	The covalent attachment of a geranylgeranyl group to a protein.	tmpzr1t_l9r_go_relaxed.owl	C-terminal protein geranylgeranylation|protein amino acid geranylgeranylation											GO:0018348		biological_process											owl:Class	
GO:0032161	biolink:NamedThing	cleavage apparatus septin structure	Any of a series of structures composed of septins and septin-associated proteins localized to the cleavage plane which are involved in cytokinesis.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0032156	biolink:NamedThing	septin cytoskeleton	The part of the cytoskeleton (the internal framework of a cell) composed of septins and associated proteins. Includes septin cytoskeleton-associated complexes.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0030900	biolink:NamedThing	forebrain development	The process whose specific outcome is the progression of the forebrain over time, from its formation to the mature structure. The forebrain is the anterior of the three primary divisions of the developing chordate brain or the corresponding part of the adult brain (in vertebrates, includes especially the cerebral hemispheres, the thalamus, and the hypothalamus and especially in higher vertebrates is the main control center for sensory and associative information processing, visceral functions, and voluntary motor functions).	tmpzr1t_l9r_go_relaxed.owl	prosencephalon development													biological_process											owl:Class	
GO:0033599	biolink:NamedThing	regulation of mammary gland epithelial cell proliferation	Any process that modulates the frequency, rate or extent of mammary gland epithelial cell proliferation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0033598	biolink:NamedThing	mammary gland epithelial cell proliferation	The multiplication or reproduction of mammary gland epithelial cells, resulting in the expansion of a cell population. Mammary gland epithelial cells make up the covering of surfaces of the mammary gland. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0035222	biolink:NamedThing	wing disc pattern formation	The process giving rise to the pattern of cell differentiation in the wing imaginal disc.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0035220	biolink:NamedThing	wing disc development	Progression of the wing disc over time, from its initial formation through to its metamorphosis to form adult structures including the wing hinge, wing blade and pleura.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0097592	biolink:NamedThing	ventral disc overlap zone	A region of the ventral disc of Giardia species (trophozoite stage) where two portions of the same array of microtubules overlap (the microtubule array makes a complete circle and overlaps on itself).	tmpzr1t_l9r_go_relaxed.owl	ventral disk overlap zone|overlap zone					Due to the asymmetric nature of the Giardia trophozoite, this term is defined spatially as the trophozoite is viewed from the dorsal side, with the two nuclei dorsal to the ventral disc, and the ventral disc toward the anterior.		pr	2014-04-03T11:12:50Z					cellular_component											owl:Class	
GO:1905568	biolink:NamedThing	regulation of ferrichrome biosynthetic process	Any process that modulates the frequency, rate or extent of ferrichrome biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of ferrichrome synthesis|regulation of ferrichrome biosynthesis|regulation of ferrichrome biosynthetic process, peptide formation|regulation of ferrichrome formation|regulation of ferrichrome anabolism|regulation of ferrichrome biosynthetic process, peptide modification							pr	2016-10-18T14:49:00Z					biological_process											owl:Class	
GO:0002025	biolink:NamedThing	norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure	A process that results in an increase in the diameter of an artery during the norepinephrine-epinephrine response to blood pressure change.	tmpzr1t_l9r_go_relaxed.owl	noradrenaline-adrenaline vasodilation involved in regulation of blood pressure|vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure|norepinephrine-epinephrine vasodilation during blood pressure regulation													biological_process											owl:Class	
GO:0001993	biolink:NamedThing	regulation of systemic arterial blood pressure by norepinephrine-epinephrine	The process in which the secretion of norepinephrine or epinephrine into the bloodstream modulates the force with which blood passes through the circulatory system.	tmpzr1t_l9r_go_relaxed.owl	noradrenaline-adrenaline regulation of blood pressure|norepinephrine-epinephrine blood pressure control|norepinephrine-epinephrine blood pressure regulation													biological_process											owl:Class	
GO:0098575	biolink:NamedThing	lumenal side of lysosomal membrane	The side (leaflet) of the lysosomal membrane that faces the lumen.	tmpzr1t_l9r_go_relaxed.owl	internal leaflet of lysosomal membrane|internal side of lysosomal membrane													cellular_component											owl:Class	
GO:0002182	biolink:NamedThing	cytoplasmic translational elongation	The successive addition of amino acid residues to a nascent polypeptide chain during protein biosynthesis in the cytoplasm.	tmpzr1t_l9r_go_relaxed.owl								hjd	2011-06-09T03:14:42Z					biological_process											owl:Class	
GO:0002181	biolink:NamedThing	cytoplasmic translation	The chemical reactions and pathways resulting in the formation of a protein in the cytoplasm. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein.	tmpzr1t_l9r_go_relaxed.owl						Note that this term applies to translation performed by cytoplasmic ribosomes, which is distinct from translation performed by organellar ribosomes. For mitochondrial translation, consider GO:0032543 'mitochondrial translation' or its child terms.		hjd	2011-06-09T03:11:53Z					biological_process											owl:Class	
GO:1902576	biolink:NamedThing	negative regulation of nuclear cell cycle DNA replication	Any process that stops, prevents or reduces the frequency, rate or extent of nuclear cell cycle DNA replication.	tmpzr1t_l9r_go_relaxed.owl	downregulation of DNA replication involved in S-phase|downregulation of DNA replication involved in S phase|downregulation of DNA replication during S phase|inhibition of DNA replication involved in S phase|inhibition of DNA replication involved in S-phase|down regulation of DNA replication involved in S phase|downregulation of nuclear cell cycle DNA replication|negative regulation of DNA replication involved in S-phase|down regulation of DNA replication involved in S-phase|down-regulation of DNA replication involved in S phase|negative regulation of DNA replication during S phase|inhibition of DNA replication during S phase|down-regulation of DNA replication involved in S-phase|negative regulation of DNA replication involved in S phase|inhibition of nuclear cell cycle DNA replication|down regulation of DNA replication during S phase|down regulation of nuclear cell cycle DNA replication|down-regulation of DNA replication during S phase|down-regulation of nuclear cell cycle DNA replication							mah	2013-12-17T14:03:02Z					biological_process											owl:Class	
GO:0009933	biolink:NamedThing	meristem structural organization	Organization of a region of tissue in a plant that is composed of one or more undifferentiated cells capable of undergoing mitosis and differentiation, thereby effecting growth and development of a plant by giving rise to more meristem or specialized tissue.	tmpzr1t_l9r_go_relaxed.owl	meristem organisation|meristem organization													biological_process											owl:Class	
GO:0097230	biolink:NamedThing	cell motility in response to potassium ion	Any process involved in the controlled self-propelled movement of a cell that results in translocation of the cell from one place to another as a result of a potassium ion stimulus.	tmpzr1t_l9r_go_relaxed.owl	K+ facilitation of cell motility|potassium ion facilitation of cell motility							pr	2012-01-25T04:39:45Z					biological_process											owl:Class	
GO:0035865	biolink:NamedThing	cellular response to potassium ion	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a potassium ion stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to K+ ion|cellular response to potassium							bf	2011-05-25T02:59:11Z					biological_process											owl:Class	
GO:0010884	biolink:NamedThing	positive regulation of lipid storage	Any process that increases the rate, frequency or extent of lipid storage. Lipid storage is the accumulation and maintenance in cells or tissues of lipids, compounds soluble in organic solvents but insoluble or sparingly soluble in aqueous solvents. Lipid reserves can be accumulated during early developmental stages for mobilization and utilization at later stages of development.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of lipid sequestration													biological_process											owl:Class	
GO:0090355	biolink:NamedThing	positive regulation of auxin metabolic process	Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving auxins, plant hormones that regulate aspects of plant growth.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of auxin metabolism							tb	2010-06-29T01:51:18Z					biological_process											owl:Class	
GO:1904236	biolink:NamedThing	negative regulation of substrate-dependent cell migration, cell attachment to substrate	Any process that stops, prevents or reduces the frequency, rate or extent of substrate-dependent cell migration, cell attachment to substrate.	tmpzr1t_l9r_go_relaxed.owl	down regulation of substrate-dependent cell migration, cell attachment to substrate|down-regulation of substrate-bound cell migration, cell attachment to substrate|negative regulation of substrate-bound cell migration, cell attachment to substrate|downregulation of substrate-dependent cell migration, cell attachment to substrate|inhibition of substrate-dependent cell migration, cell attachment to substrate|downregulation of substrate-bound cell migration, cell attachment to substrate|down regulation of substrate-bound cell migration, cell attachment to substrate|down-regulation of substrate-dependent cell migration, cell attachment to substrate|inhibition of substrate-bound cell migration, cell attachment to substrate							pga	2015-05-15T13:30:05Z					biological_process											owl:Class	
GO:2000182	biolink:NamedThing	regulation of progesterone biosynthetic process	Any process that modulates the frequency, rate or extent of progesterone biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of progesterone anabolism|regulation of progesterone biosynthesis|regulation of progesterone formation|regulation of progesterone synthesis							dph	2010-10-14T07:36:06Z					biological_process											owl:Class	
GO:0006701	biolink:NamedThing	progesterone biosynthetic process	The chemical reactions and pathways resulting in the formation of progesterone, a steroid hormone produced in the ovary which prepares and maintains the uterus for pregnancy. Also found in plants.	tmpzr1t_l9r_go_relaxed.owl	progesterone anabolism|progesterone formation|progesterone biosynthesis|progesterone synthesis													biological_process											owl:Class	
GO:0090259	biolink:NamedThing	regulation of retinal ganglion cell axon guidance	Any process that modulates the frequency, rate, or extent of retinal ganglion cell axon guidance, the process in which the migration of an axon growth cone of a retinal ganglion cell (RGC) is directed to its target in the brain in response to a combination of attractive and repulsive cues.	tmpzr1t_l9r_go_relaxed.owl								tb	2010-02-03T04:13:59Z					biological_process											owl:Class	
GO:0031290	biolink:NamedThing	retinal ganglion cell axon guidance	The process in which the migration of an axon growth cone of a retinal ganglion cell (RGC) is directed to its target in the brain in response to a combination of attractive and repulsive cues.	tmpzr1t_l9r_go_relaxed.owl	retinal ganglion cell axon pathfinding													biological_process											owl:Class	
GO:0098570	biolink:NamedThing	stromal side of plastid inner membrane	The side (leaflet) of the plastid inner membrane that faces the stroma, and any proteins embedded in it or loosely bound to its surface.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0031518	biolink:NamedThing	CBF3 complex	A multisubunit protein complex that binds to centromeric DNA and initiates kinetochore assembly. In yeast, this complex consists of four subunits, namely Ctf13p, Skp1p, Cep3p and Cbf2p.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0014744	biolink:NamedThing	positive regulation of muscle adaptation	Any process that activates or increases the frequency, rate or extent of muscle adaptation.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of muscle plasticity													biological_process											owl:Class	
GO:0001547	biolink:NamedThing	antral ovarian follicle growth	Increase in size of antral follicles due to cell proliferation and/or growth of the antral cavity.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0045445	biolink:NamedThing	myoblast differentiation	The process in which a relatively unspecialized cell acquires specialized features of a myoblast. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into striated muscle fibers.	tmpzr1t_l9r_go_relaxed.owl	myoblast cell differentiation													biological_process											owl:Class	
GO:0071353	biolink:NamedThing	cellular response to interleukin-4	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-4 stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to IL-4							mah	2009-12-11T02:51:00Z					biological_process											owl:Class	
GO:1990703	biolink:NamedThing	integral component of Golgi medial cisterna membrane	The component of the Golgi medial membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.	tmpzr1t_l9r_go_relaxed.owl	integral component of medial-Golgi cisterna membrane							bhm	2015-03-16T16:05:25Z					cellular_component											owl:Class	
GO:1990675	biolink:NamedThing	Golgi medial cisterna membrane	The lipid bilayer surrounding any of the thin, flattened compartments that form the medial portion of the Golgi complex.	tmpzr1t_l9r_go_relaxed.owl	medial-Golgi cisterna membrane							bhm	2015-03-02T11:50:29Z					cellular_component											owl:Class	
GO:0048904	biolink:NamedThing	anterior lateral line neuromast cupula development	The process whose specific outcome is the progression of the anterior lateral line neuromast cupula over time, from its formation to the mature structure. The cupula is secreted by mantle cells and the ciliary bundles of all of the hair cells of the neuromast are embedded in it. The cupula provides a mechanical linkage between the hair cells and the external hydrodynamic environment. The cupula of superficial neuromasts grows continuously, while the height of the cupula of canal neuromasts is limited by canal diameter.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0048901	biolink:NamedThing	anterior lateral line neuromast development	The process whose specific outcome is the progression of the anterior lateral line neuromast over time, from its formation to the mature structure. The neuromast is the sensory receptor of the anterior lateral line system and is composed of a population of sensory hair cells, and nonsensory supporting cells and mantle cells. Neuromast are located superficially on the epithelium or in lateral line canals.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0106074	biolink:NamedThing	aminoacyl-tRNA metabolism involved in translational fidelity	Any process which detects an amino-acid acetylated tRNA is charged with the correct amino acid, or removes incorrect amino acids from a charged tRNA. This process can be performed by tRNA synthases, or by subsequent reactions after tRNA aminoacylation.	tmpzr1t_l9r_go_relaxed.owl	aminoacyl-tRNA proofreading|aminoacyl-tRNA correction|aminoacyl-tRNA editin							hjd	2017-11-29T17:48:39Z					biological_process											owl:Class	
GO:0098778	biolink:NamedThing	curli subunit secretion coupled to curli assembly	The secretion of soluble curli subunits through the outer membrane, coupled to nucleation of curli fiber formation at the membrane surface.	tmpzr1t_l9r_go_relaxed.owl	extracellular nucleation-precipitation pathway													biological_process											owl:Class	
GO:0098775	biolink:NamedThing	curli assembly	The process of assembly of curli, extracellular fibers produced by enteric bacteria.  This process occurs outside the cell, where it is coupled to secretion across the cell outer membrane via nucleation by elements of the transporter complex.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0005673	biolink:NamedThing	transcription factor TFIIE complex	A transcription factor which in humans consists of a complex of two alpha and two beta chains. Recruits TFIIH to the initiation complex and helps activate both RNA polymerase II and TFIIH.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0072565	biolink:NamedThing	endothelial microparticle formation	The cellular component organization process in which microparticles bud off from an endothelial cell.	tmpzr1t_l9r_go_relaxed.owl	endothelial microparticle release|endothelial microparticle generation							mah	2011-01-28T02:21:58Z					biological_process											owl:Class	
GO:0045063	biolink:NamedThing	T-helper 1 cell differentiation	The process in which a relatively unspecialized T cell acquires the specialized features of a T-helper 1 (Th1) cell. A Th1 cell is a CD4-positive, alpha-beta T cell that has the phenotype T-bet-positive and produces interferon-gamma.	tmpzr1t_l9r_go_relaxed.owl	T-helper 1 cell development					Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.								biological_process											owl:Class	
GO:0042088	biolink:NamedThing	T-helper 1 type immune response	An immune response which is associated with resistance to intracellular bacteria, fungi, and protozoa, and pathological conditions such as arthritis, and which is typically orchestrated by the production of particular cytokines by T-helper 1 cells, most notably interferon-gamma, IL-2, and lymphotoxin.	tmpzr1t_l9r_go_relaxed.owl	Th1 immune response													biological_process											owl:Class	
GO:1990757	biolink:NamedThing	ubiquitin ligase activator activity	Binds to and increases the activity of a ubiquitin ligase.	tmpzr1t_l9r_go_relaxed.owl	mitotic anaphase-promoting complex activator activity							vw	2015-06-01T08:53:04Z			GO:0061636		molecular_function											owl:Class	
GO:1904668	biolink:NamedThing	positive regulation of ubiquitin protein ligase activity	Any process that activates or increases the frequency, rate or extent of ubiquitin protein ligase activity.	tmpzr1t_l9r_go_relaxed.owl	activation of E3|activation of anaphase-promoting complex activity|up-regulation of ubiquitin protein ligase activity|positive regulation of ubiquitin ligase activity|up-regulation of protein ubiquitination activity|activation of APC-fizzy related complex activity|up regulation of ubiquitin ligase activity|up-regulation of E3|positive regulation of E3|upregulation of ubiquitin protein ligase activity|activation of ubiquitin ligase activity|up regulation of APC-fizzy related complex activity|upregulation of ubiquitin ligase activity|upregulation of APC-fizzy related complex activity|up regulation of E3|upregulation of E3|positive regulation of APC-fizzy related complex activity|positive regulation of protein ubiquitination activity|up-regulation of APC-fizzy related complex activity|activation of APC-Cdc20 complex activity|activation of protein ubiquitination activity|up-regulation of ubiquitin ligase activity|up regulation of protein ubiquitination activity|up regulation of ubiquitin protein ligase activity|upregulation of protein ubiquitination activity|activation of ubiquitin protein ligase activity							dph	2015-09-08T15:27:11Z			GO:0090623|GO:0051488|GO:0007092|GO:1903835		biological_process											owl:Class	
GO:0010057	biolink:NamedThing	trichoblast fate specification	The process involved in the specification of a trichoblast.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:2000616	biolink:NamedThing	negative regulation of histone H3-K9 acetylation	Any process that stops, prevents or reduces the frequency, rate or extent of histone H3-K9 acetylation.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of histone H3 acetylation at K9|negative regulation of histone H3K9 acetylation							vk	2011-04-18T03:16:04Z					biological_process											owl:Class	
GO:0043970	biolink:NamedThing	histone H3-K9 acetylation	The modification of histone H3 by the addition of an acetyl group to a lysine residue at position 9 of the histone.	tmpzr1t_l9r_go_relaxed.owl	histone H3K9 acetylation|histone H3 acetylation at K9													biological_process											owl:Class	
GO:0036093	biolink:NamedThing	germ cell proliferation	The multiplication or reproduction of germ cells, reproductive cells in multicellular organisms, resulting in the expansion of a cell population.	tmpzr1t_l9r_go_relaxed.owl								bf	2012-01-17T04:06:27Z					biological_process											owl:Class	
GO:0097533	biolink:NamedThing	cellular stress response to acid chemical	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in cellular homeostasis caused by the chemical structure of the anion portion of a dissociated acid (rather than the acid acting as a proton donor). The acid chemical may be in gaseous, liquid or solid form.	tmpzr1t_l9r_go_relaxed.owl	cellular stress response to acid|cellular response to acid stress							pr	2013-11-12T13:07:12Z					biological_process											owl:Class	
GO:0071229	biolink:NamedThing	cellular response to acid chemical	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by the chemical structure of the anion portion of the dissociated acid (rather than the acid acting as a proton donor). The acid chemical may be in gaseous, liquid or solid form.	tmpzr1t_l9r_go_relaxed.owl	cellular response to acid|cellular response to oxoanion|cellular response to acid anion					This term should be used to describe a response to a specific acid as a chemical. E.g., if a cell were responding to glutamate, then the response would be glutamate-specific; the cell is actually responding to the chemical structure of the anion portion of the dissociated acid. Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. If annotating experiments where an acid is playing a role as a proton donor, please annotate to GO:0071468 'cellular response to acidic pH' instead.		mah	2009-12-03T02:07:23Z					biological_process											owl:Class	
GO:0001570	biolink:NamedThing	vasculogenesis	The differentiation of endothelial cells from progenitor cells during blood vessel development, and the de novo formation of blood vessels and tubes.	tmpzr1t_l9r_go_relaxed.owl	vascular morphogenesis				Wikipedia:Vasculogenesis									biological_process											owl:Class	
GO:0061625	biolink:NamedThing	glycolytic process through fructose-1-phosphate	The chemical reactions and pathways resulting in the breakdown of fructose into pyruvate through a fructose-1-phosphate intermediate, with the concomitant production of ATP and NADH.	tmpzr1t_l9r_go_relaxed.owl								dph	2014-04-29T13:04:10Z					biological_process											owl:Class	
GO:0060738	biolink:NamedThing	epithelial-mesenchymal signaling involved in prostate gland development	Any process that results in the transfer of information from an epithelial cell to a mesenchymal cell where it is interpreted and contributes to the progression of the prostate gland over time.	tmpzr1t_l9r_go_relaxed.owl	epithelial-mesenchymal signalling involved in prostate gland development							dph	2009-06-15T09:31:31Z					biological_process											owl:Class	
GO:0030850	biolink:NamedThing	prostate gland development	The process whose specific outcome is the progression of the prostate gland over time, from its formation to the mature structure. The prostate gland is a partly muscular, partly glandular body that is situated near the base of the mammalian male urethra and secretes an alkaline viscid fluid which is a major constituent of the ejaculatory fluid.	tmpzr1t_l9r_go_relaxed.owl	prostate development													biological_process											owl:Class	
GO:1902034	biolink:NamedThing	negative regulation of hematopoietic stem cell proliferation	Any process that stops, prevents or reduces the frequency, rate or extent of hematopoietic stem cell proliferation.	tmpzr1t_l9r_go_relaxed.owl	down regulation of hemopoietic stem cell proliferation|down regulation of hematopoietic stem cell proliferation|down-regulation of hemopoietic stem cell proliferation|down-regulation of hematopoietic stem cell proliferation|negative regulation of hemopoietic stem cell proliferation|downregulation of hematopoietic stem cell proliferation|inhibition of hemopoietic stem cell proliferation|inhibition of hematopoietic stem cell proliferation|downregulation of hemopoietic stem cell proliferation							ss	2013-04-02T05:13:24Z					biological_process											owl:Class	
GO:0046844	biolink:NamedThing	chorion micropyle formation	Establishment of the micropyle, a single cone-shaped specialization of the chorion that allows sperm entry into the egg prior to fertilization.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0002913	biolink:NamedThing	positive regulation of lymphocyte anergy	Any process that activates or increases the frequency, rate, or extent of lymphocyte anergy.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of lymphocyte anergy|activation of lymphocyte anergy|stimulation of lymphocyte anergy|up regulation of lymphocyte anergy|upregulation of lymphocyte anergy													biological_process											owl:Class	
GO:0002249	biolink:NamedThing	lymphocyte anergy	Any process contributing to lymphocyte anergy, a state of functional inactivation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0043116	biolink:NamedThing	negative regulation of vascular permeability	Any process that reduces the extent to which blood vessels can be pervaded by fluid.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of vascular permeability|down regulation of vascular permeability|downregulation of vascular permeability|inhibition of vascular permeability													biological_process											owl:Class	
GO:0021669	biolink:NamedThing	rhombomere 6 formation	The process that gives rise to rhombomere 6. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0000080	biolink:NamedThing	mitotic G1 phase	The cell cycle 'gap' phase which is the interval between the completion of DNA segregation by mitosis and the beginning of DNA synthesis.	tmpzr1t_l9r_go_relaxed.owl	G1 phase of mitotic cell cycle					Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).								biological_process											owl:Class	
GO:1903830	biolink:NamedThing	magnesium ion transmembrane transport	The directed movement of magnesium ion across a membrane.	tmpzr1t_l9r_go_relaxed.owl								mcc	2015-01-21T17:38:30Z					biological_process											owl:Class	
GO:0033168	biolink:NamedThing	conversion of ds siRNA to ss siRNA involved in RNA interference	The process in which double-stranded siRNA molecules are converted to single-stranded siRNAs; required for the formation of a mature RITS complex during RNA interference.	tmpzr1t_l9r_go_relaxed.owl	RNA interference, conversion of ds siRNA to ss siRNA													biological_process											owl:Class	
GO:0016246	biolink:NamedThing	RNA interference	The process in which double-stranded RNAs silence cognate genes. Involves posttranscriptional gene inactivation ('silencing') both of transgenes or dsRNA introduced into a germline, and of the host gene(s) homologous to the transgenes or dsRNA. This silencing is triggered by the introduction of transgenes or double-stranded RNA (dsRNA), and can occur through a specific decrease in the level of mRNA, or by negative regulation of translation, of both host genes and transgenes.	tmpzr1t_l9r_go_relaxed.owl	posttranscriptional gene silencing by siRNA|RNAi				Wikipedia:RNA_interference	Note that this term refers specifically to posttranscriptional mechanisms by which small interfering RNAs down-regulate gene expression. Also consider annotating to other descendants of 'gene silencing by RNA ; GO:0031047'.								biological_process											owl:Class	
GO:0070494	biolink:NamedThing	regulation of thrombin-activated receptor signaling pathway	Any process that modulates the frequency, rate or extent of a thrombin-activated receptor signaling pathway activity. A thrombin receptor signaling pathway is the series of molecular signals generated as a consequence of a thrombin-activated receptor binding to one of its physiological ligands.	tmpzr1t_l9r_go_relaxed.owl	regulation of thrombin receptor signaling pathway|regulation of thrombin receptor signalling pathway													biological_process											owl:Class	
GO:0070493	biolink:NamedThing	thrombin-activated receptor signaling pathway	The series of molecular signals generated as a consequence of a thrombin-activated receptor binding to one of its physiological ligands.	tmpzr1t_l9r_go_relaxed.owl	thrombin receptor signaling pathway|thrombin receptor signalling pathway													biological_process											owl:Class	
GO:0045112	biolink:NamedThing	integrin biosynthetic process	The chemical reactions and pathways resulting in the formation of integrins, a large family of transmembrane proteins that act as receptors for cell-adhesion molecules.	tmpzr1t_l9r_go_relaxed.owl	integrin biosynthesis|integrin formation|integrin anabolism|integrin synthesis													biological_process											owl:Class	
GO:0033040	biolink:NamedThing	sour taste receptor activity	Combining with soluble sour compounds to initiate a change in cell activity. These receptors are responsible for the sense of sour taste.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0045929	biolink:NamedThing	positive regulation of juvenile hormone metabolic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving juvenile hormone.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of juvenile hormone metabolism|upregulation of juvenile hormone metabolic process|activation of juvenile hormone metabolic process|stimulation of juvenile hormone metabolic process|up regulation of juvenile hormone metabolic process|up-regulation of juvenile hormone metabolic process													biological_process											owl:Class	
GO:0090080	biolink:NamedThing	positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway	The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands resulting in an increase in the rate or frequency of a MAPKKK cascade.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of MAPKKK cascade by fibroblast growth factor receptor signalling pathway							tb	2009-10-19T11:30:22Z					biological_process											owl:Class	
GO:1904183	biolink:NamedThing	negative regulation of pyruvate dehydrogenase activity	Any process that stops, prevents or reduces the frequency, rate or extent of pyruvate dehydrogenase activity.	tmpzr1t_l9r_go_relaxed.owl	downregulation of pyruvate dehydrogenase activity|down-regulation of pyruvic acid dehydrogenase activity|down-regulation of pyruvate dehydrogenase activity|inhibition of pyruvic dehydrogenase activity|negative regulation of pyruvic dehydrogenase activity|inhibition of pyruvate dehydrogenase activity|down regulation of pyruvic acid dehydrogenase activity|negative regulation of pyruvic acid dehydrogenase activity|downregulation of pyruvic acid dehydrogenase activity|down regulation of pyruvic dehydrogenase activity|inhibition of pyruvic acid dehydrogenase activity|down regulation of pyruvate dehydrogenase activity|downregulation of pyruvic dehydrogenase activity|down-regulation of pyruvic dehydrogenase activity							dph	2015-05-05T14:17:33Z					biological_process											owl:Class	
GO:0000290	biolink:NamedThing	deadenylation-dependent decapping of nuclear-transcribed mRNA	Cleavage of the 5'-cap of a nuclear mRNA triggered by shortening of the poly(A) tail to below a minimum functional length.	tmpzr1t_l9r_go_relaxed.owl	deadenylylation-dependent decapping|deadenylation-dependent decapping of nuclear mRNA													biological_process											owl:Class	
GO:1902255	biolink:NamedThing	positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator	Any process that activates or increases the frequency, rate or extent of intrinsic apoptotic signaling pathway by p53 class mediator.	tmpzr1t_l9r_go_relaxed.owl	upregulation of intrinsic apoptotic signaling pathway by signal transduction by p53 class mediator|activation of intrinsic apoptotic signaling pathway by p53 class mediator|up regulation of intrinsic apoptotic signaling pathway by signal transduction by p53 class mediator|up regulation of intrinsic apoptotic signaling pathway by p53 class mediator|upregulation of intrinsic apoptotic signaling pathway by p53 class mediator|positive regulation of intrinsic apoptotic signaling pathway by signal transduction by p53 class mediator|up regulation of signal transduction by p53 class mediator resulting in induction of apoptosis|activation of signal transduction by p53 class mediator resulting in induction of apoptosis|up-regulation of intrinsic apoptotic signaling pathway by signal transduction by p53 class mediator|positive regulation of signal transduction by p53 class mediator resulting in induction of apoptosis|upregulation of signal transduction by p53 class mediator resulting in induction of apoptosis|activation of intrinsic apoptotic signaling pathway by signal transduction by p53 class mediator|up-regulation of intrinsic apoptotic signaling pathway by p53 class mediator|up-regulation of signal transduction by p53 class mediator resulting in induction of apoptosis							rl	2013-06-20T19:41:54Z					biological_process											owl:Class	
GO:1905870	biolink:NamedThing	positive regulation of 3'-UTR-mediated mRNA stabilization	Any process that activates or increases the frequency, rate or extent of 3'-UTR-mediated mRNA stabilization.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of 3'-untranslated region-mediated mRNA stabilization|activation of 3'-untranslated region-mediated mRNA stabilization|upregulation of 3'-UTR-mediated mRNA stabilization|up regulation of 3'-untranslated region-mediated mRNA stabilization|upregulation of 3'-untranslated region-mediated mRNA stabilization|activation of 3'-UTR-mediated mRNA stabilization|up-regulation of 3'-untranslated region-mediated mRNA stabilization|up-regulation of 3'-UTR-mediated mRNA stabilization|up regulation of 3'-UTR-mediated mRNA stabilization							rz	2017-01-27T11:51:55Z					biological_process											owl:Class	
GO:1904940	biolink:NamedThing	negative regulation of DNA nucleotidylexotransferase activity	Any process that stops, prevents or reduces the frequency, rate or extent of DNA nucleotidylexotransferase activity.	tmpzr1t_l9r_go_relaxed.owl	inhibition of TdT|negative regulation of deoxyribonucleic nucleotidyltransferase activity|inhibition of deoxyribonucleic nucleotidyltransferase activity|down regulation of terminal addition enzyme activity|negative regulation of terminal deoxyribonucleotidyltransferase activity|down regulation of deoxyribonucleic nucleotidyltransferase activity|down regulation of addase activity|negative regulation of terminal deoxynucleotide transferase activity|downregulation of DNA nucleotidylexotransferase activity|down-regulation of deoxyribonucleic nucleotidyltransferase activity|down-regulation of terminal addition enzyme activity|down regulation of terminal deoxynucleotidyltransferase activity|negative regulation of terminal deoxynucleotidyltransferase activity|down regulation of deoxynucleotidyl terminal transferase activity|inhibition of terminal deoxynucleotide transferase activity|downregulation of terminal deoxyribonucleotidyltransferase activity|down regulation of nucleoside-triphosphate:DNA deoxynucleotidylexotransferase activity|down-regulation of DNA nucleotidylexotransferase activity|inhibition of DNA nucleotidylexotransferase activity|inhibition of terminal transferase activity|down regulation of terminal transferase activity|down-regulation of terminal transferase activity|downregulation of terminal addition enzyme activity|down-regulation of deoxynucleotidyl terminal transferase activity|negative regulation of terminal transferase activity|downregulation of nucleoside-triphosphate:DNA deoxynucleotidylexotransferase activity|negative regulation of addase activity|negative regulation of TdT|downregulation of addase activity|downregulation of deoxyribonucleic nucleotidyltransferase activity|down-regulation of terminal deoxynucleotide transferase activity|inhibition of addase activity|downregulation of terminal deoxynucleotidyltransferase activity|down-regulation of terminal deoxynucleotidyltransferase activity|downregulation of deoxynucleotidyl terminal transferase activity|down regulation of terminal deoxynucleotide transferase activity|down-regulation of TdT|down-regulation of addase activity|inhibition of terminal addition enzyme activity|negative regulation of deoxyribonucleic acid nucleotidyltransferase activity|down regulation of deoxyribonucleic acid nucleotidyltransferase activity|downregulation of terminal deoxynucleotide transferase activity|inhibition of nucleoside-triphosphate:DNA deoxynucleotidylexotransferase activity|down regulation of terminal deoxyribonucleotidyltransferase activity|inhibition of terminal deoxyribonucleotidyltransferase activity|downregulation of terminal transferase activity|down-regulation of terminal deoxyribonucleotidyltransferase activity|down regulation of TdT|negative regulation of deoxynucleotidyl terminal transferase activity|inhibition of terminal deoxynucleotidyltransferase activity|inhibition of deoxyribonucleic acid nucleotidyltransferase activity|downregulation of deoxyribonucleic acid nucleotidyltransferase activity|down regulation of DNA nucleotidylexotransferase activity|negative regulation of nucleoside-triphosphate:DNA deoxynucleotidylexotransferase activity|downregulation of TdT|down-regulation of deoxyribonucleic acid nucleotidyltransferase activity|down-regulation of nucleoside-triphosphate:DNA deoxynucleotidylexotransferase activity|negative regulation of terminal addition enzyme activity|inhibition of deoxynucleotidyl terminal transferase activity							bc	2016-02-02T15:16:05Z					biological_process											owl:Class	
GO:0003912	biolink:NamedThing	DNA nucleotidylexotransferase activity	Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).	tmpzr1t_l9r_go_relaxed.owl	addase activity|terminal deoxynucleotide transferase activity|terminal deoxyribonucleotidyltransferase activity|deoxynucleotidyl terminal transferase activity|terminal deoxynucleotidyltransferase activity|deoxyribonucleic acid nucleotidyltransferase activity|TdT|deoxyribonucleic nucleotidyltransferase activity|nucleoside-triphosphate:DNA deoxynucleotidylexotransferase activity|terminal transferase activity|terminal addition enzyme activity				EC:2.7.7.31|MetaCyc:DNA-NUCLEOTIDYLEXOTRANSFERASE-RXN									molecular_function											owl:Class	
GO:1990504	biolink:NamedThing	dense core granule exocytosis	The secretion of molecules (e.g. neuropeptides, insulin-related peptides or neuromodulators such as serotonin and dopamine) contained within a membrane-bounced dense core granule by fusion of the granule with the plasma membrane of a cell in response to increased cytosolic calcium levels.	tmpzr1t_l9r_go_relaxed.owl	dense core vesicle exocytosis							kmv	2014-09-30T21:05:50Z					biological_process											owl:Class	
GO:0004057	biolink:NamedThing	arginyltransferase activity	Catalysis of the reaction: L-arginyl-tRNA + protein = tRNA + L-arginyl-protein.	tmpzr1t_l9r_go_relaxed.owl	arginyl-tRNA-protein transferase activity|arginyl-tRNA protein transferase activity|L-arginyl-tRNA:protein arginyltransferase activity|arginyl-tRNA--protein transferase activity|arginine transferase activity|arginyl-transfer ribonucleate-protein transferase activity|arginyl-transfer ribonucleate-protein aminoacyltransferase activity				EC:2.3.2.8|MetaCyc:ARGINYLTRANSFERASE-RXN|RHEA:10208							GO:0042172		molecular_function											owl:Class	
GO:0016598	biolink:NamedThing	protein arginylation	The conjugation of arginine to the N-terminal aspartate or glutamate of a protein; required for the degradation of the protein via the ubiquitin pathway.	tmpzr1t_l9r_go_relaxed.owl	protein amino acid arginylation											GO:0019130		biological_process											owl:Class	
GO:0015156	biolink:NamedThing	melibiose transmembrane transporter activity	Enables the transfer of melibiose from one side of a membrane to the other. Melibiose is the disaccharide 6-O-alpha-D-galactopyranosyl-D-glucose and occurs as a constituent of the trisaccharide raffinose or in the exudates and nectaries of a number of plants.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0015769	biolink:NamedThing	melibiose transport	The directed movement of melibiose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Melibiose is the disaccharide 6-O-alpha-D-galactopyranosyl-D-glucose.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1903893	biolink:NamedThing	positive regulation of ATF6-mediated unfolded protein response	Any process that activates or increases the frequency, rate or extent of the ATF6-mediated unfolded protein response.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of ATF6 signaling in response to endoplasmic reticulum stress|activation of endoplasmic reticulum unfolded protein response; ATF6 signaling|up-regulation of UPR signaling by ATF6 stress sensor|upregulation of ATF6-beta UPR branch|activation of activating transcription factor 6 signaling in unfolded protein response|upregulation of ATF6-mediated unfolded protein response|activation of UPR signaling by ATF6 stress sensor|up regulation of UPR signaling by ATF6 stress sensor|positive regulation of ATF6-alpha UPR branch|up regulation of activating transcription factor 6 signaling in unfolded protein response|up regulation of ATF6 branch of UPR|up-regulation of ATF6-beta UPR branch|up-regulation of ATF6-mediated unfolded protein response|up regulation of ATF6-beta UPR branch|upregulation of ATF6 branch of UPR|upregulation of ATF6-alpha UPR branch|activation of ATF6 signaling in response to endoplasmic reticulum stress|up-regulation of endoplasmic reticulum unfolded protein response; ATF6 signaling|activation of ATF6-mediated unfolded protein response|positive regulation of UPR signaling by ATF6 stress sensor|activation of ATF6-alpha UPR branch|up regulation of ATF6-alpha UPR branch|upregulation of UPR signaling by ATF6 stress sensor|up-regulation of ATF6 branch of UPR|positive regulation of endoplasmic reticulum unfolded protein response; ATF6 signaling|up regulation of ATF6-mediated unfolded protein response|activation of ATF6-beta UPR branch|upregulation of ATF6 signaling in response to endoplasmic reticulum stress|up-regulation of ATF6-alpha UPR branch|positive regulation of ATF6-beta UPR branch|upregulation of endoplasmic reticulum unfolded protein response; ATF6 signaling|positive regulation of activating transcription factor 6 signaling in unfolded protein response|upregulation of activating transcription factor 6 signaling in unfolded protein response|positive regulation of ATF6 branch of UPR|up-regulation of activating transcription factor 6 signaling in unfolded protein response|activation of ATF6 branch of UPR|up regulation of ATF6 signaling in response to endoplasmic reticulum stress|up regulation of endoplasmic reticulum unfolded protein response; ATF6 signaling|positive regulation of ATF6 signaling in response to endoplasmic reticulum stress							bf	2015-02-09T10:17:36Z					biological_process											owl:Class	
GO:0031151	biolink:NamedThing	histone methyltransferase activity (H3-K79 specific)	Catalysis of the reaction: S-adenosyl-L-methionine + histone H3 L-lysine (position 79) = S-adenosyl-L-homocysteine + histone H3 N6-methyl-L-lysine (position 79). This reaction is the addition of a methyl group onto lysine at position 79 of the histone H3 protein.	tmpzr1t_l9r_go_relaxed.owl	histone methylase activity (H3-K79 specific)|histone lysine N-methyltransferase activity (H3-K79 specific)													molecular_function											owl:Class	
GO:2000151	biolink:NamedThing	negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis	Any process that stops, prevents, or reduces the frequency, rate or extent of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-10-01T07:11:15Z					biological_process											owl:Class	
GO:1905654	biolink:NamedThing	regulation of artery smooth muscle contraction	Any process that modulates the frequency, rate or extent of artery smooth muscle contraction.	tmpzr1t_l9r_go_relaxed.owl								rph	2016-11-09T12:34:46Z					biological_process											owl:Class	
GO:0014824	biolink:NamedThing	artery smooth muscle contraction	A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the artery. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The artery is a vessel carrying blood away from the heart.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0050935	biolink:NamedThing	iridophore differentiation	The process in which a relatively unspecialized cell acquires the specialized features of an iridophore. Iridophores are pigment cells derived from the neural crest. They contain guanidine or other purine crystals deposited in stacks called reflecting platets or iridisomes. This gives them a silver, gold, or iridescent appearance.	tmpzr1t_l9r_go_relaxed.owl	iridophore cell differentiation													biological_process											owl:Class	
GO:0062231	biolink:NamedThing	positive regulation of larval somatic muscle development	Any process that increases the rate, frequency or extent of larval somatic muscle development.	tmpzr1t_l9r_go_relaxed.owl								dph	2020-03-16T13:49:16Z					biological_process											owl:Class	
GO:0046458	biolink:NamedThing	hexadecanal metabolic process	The chemical reactions and pathways involving hexadecanal, the C16 straight chain aldehyde.	tmpzr1t_l9r_go_relaxed.owl	hexadecanal metabolism													biological_process											owl:Class	
GO:1901095	biolink:NamedThing	positive regulation of protein homotetramerization	Any process that activates or increases the frequency, rate or extent of protein homotetramerization.	tmpzr1t_l9r_go_relaxed.owl	up regulation of protein homotetramer biosynthetic process|activation of protein homotetramerization|up-regulation of protein homotetramerization|upregulation of protein homotetramer biosynthesis|up-regulation of protein homotetramer formation|up regulation of protein homotetramer formation|up regulation of protein homotetramer biosynthesis|up regulation of protein homotetramer assembly|positive regulation of protein homotetramer biosynthetic process|upregulation of protein homotetramer formation|activation of protein homotetramer biosynthetic process|up regulation of protein homotetramerization|upregulation of protein homotetramerization|positive regulation of protein homotetramer assembly|up-regulation of protein homotetramer biosynthetic process|activation of protein homotetramer formation|upregulation of protein homotetramer assembly|activation of protein homotetramer biosynthesis|positive regulation of protein homotetramer biosynthesis|upregulation of protein homotetramer biosynthetic process|positive regulation of protein homotetramer formation|activation of protein homotetramer assembly|up-regulation of protein homotetramer biosynthesis|up-regulation of protein homotetramer assembly							pm	2012-07-06T12:58:06Z					biological_process											owl:Class	
GO:0051289	biolink:NamedThing	protein homotetramerization	The formation of a protein homotetramer, a macromolecular structure consisting of four noncovalently associated identical subunits.	tmpzr1t_l9r_go_relaxed.owl	protein homotetramer formation|protein homotetramer biosynthetic process|protein homotetramer biosynthesis|protein homotetramer assembly													biological_process											owl:Class	
GO:1902088	biolink:NamedThing	plant-type cell wall loosening involved in abscission	Any plant-type cell wall loosening that is involved in abscission.	tmpzr1t_l9r_go_relaxed.owl	cellulose and pectin-containing cell wall loosening involved in abscission							tb	2013-04-26T18:34:45Z					biological_process											owl:Class	
GO:0009838	biolink:NamedThing	abscission	The controlled shedding of a body part.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Abscission									biological_process											owl:Class	
GO:0031257	biolink:NamedThing	cell trailing edge membrane	The portion of the plasma membrane surrounding the trailing edge of a motile cell.	tmpzr1t_l9r_go_relaxed.owl	trailing edge membrane													cellular_component											owl:Class	
GO:0031254	biolink:NamedThing	cell trailing edge	The area of a motile cell opposite to the direction of movement.	tmpzr1t_l9r_go_relaxed.owl	back of cell|trailing edge													cellular_component											owl:Class	
GO:0002782	biolink:NamedThing	antifungal peptide secretion	The regulated release of an antifungal peptide from a cell or a tissue.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0150076	biolink:NamedThing	neuroinflammatory response	The immediate defensive reaction by neural vertebrate tissue to infection or injury caused by chemical or physical agents.	tmpzr1t_l9r_go_relaxed.owl	nervous tissue inflammatory response|neural tissue inflammatory response|nerve tissue inflammatory response							bc	2018-07-26T12:25:34Z					biological_process											owl:Class	
GO:0001845	biolink:NamedThing	phagolysosome assembly	The process that results in the fusion of a phagosome, a vesicle formed by phagocytosis, with a lysosome.	tmpzr1t_l9r_go_relaxed.owl	phagolysosome formation|late phagosome biosynthesis|late phagosome formation													biological_process											owl:Class	
GO:1902831	biolink:NamedThing	positive regulation of spinal cord association neuron differentiation	Any process that activates or increases the frequency, rate or extent of spinal cord association neuron differentiation.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of spinal cord dorsal interneuron differentiation|up regulation of spinal cord dorsal interneuron differentiation|positive regulation of spinal cord dorsal interneuron differentiation|activation of spinal cord association neuron differentiation|activation of spinal cord dorsal interneuron differentiation|up-regulation of spinal cord association neuron differentiation|upregulation of spinal cord dorsal interneuron differentiation|upregulation of spinal cord association neuron differentiation|up regulation of spinal cord association neuron differentiation							mr	2014-03-31T17:12:38Z					biological_process											owl:Class	
GO:0021527	biolink:NamedThing	spinal cord association neuron differentiation	The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of association neurons. Association neurons are cells located in the dorsal portion of the spinal cord that integrate sensory input. Differentiation includes the processes involved in commitment of a cell to a specific fate.	tmpzr1t_l9r_go_relaxed.owl	spinal cord dorsal interneuron differentiation													biological_process											owl:Class	
GO:0061870	biolink:NamedThing	positive regulation of hepatic stellate cell migration	Any process that increases the frequency, rate or extent of hepatic stellate cell migration.	tmpzr1t_l9r_go_relaxed.owl								dph	2017-05-01T13:17:23Z					biological_process											owl:Class	
GO:0009546	biolink:NamedThing	plasmodesmatal cytoplasmic sleeve	The space between the plasma membrane and the desmotubule of a plasmodesma.	tmpzr1t_l9r_go_relaxed.owl	plasmodesmatal cytoplasmic annulus													cellular_component											owl:Class	
GO:0010793	biolink:NamedThing	regulation of mRNA export from nucleus	Any process that modulates the frequency, rate or extent of the directed movement of mRNA from the nucleus to the cytoplasm.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0006406	biolink:NamedThing	mRNA export from nucleus	The directed movement of mRNA from the nucleus to the cytoplasm.	tmpzr1t_l9r_go_relaxed.owl	mRNA-nucleus export|mRNA transport from nucleus to cytoplasm|mRNA export from cell nucleus|mRNA export out of nucleus													biological_process											owl:Class	
GO:0030813	biolink:NamedThing	positive regulation of nucleotide catabolic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of nucleotides.	tmpzr1t_l9r_go_relaxed.owl	up regulation of nucleotide catabolic process|up-regulation of nucleotide catabolic process|stimulation of nucleotide catabolic process|positive regulation of nucleotide breakdown|positive regulation of nucleotide catabolism|upregulation of nucleotide catabolic process|positive regulation of nucleotide degradation|activation of nucleotide catabolic process													biological_process											owl:Class	
GO:0055007	biolink:NamedThing	cardiac muscle cell differentiation	The process in which a cardiac muscle precursor cell acquires specialized features of a cardiac muscle cell. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction.	tmpzr1t_l9r_go_relaxed.owl	cardiomyocyte differentiation|heart muscle cell differentiation													biological_process											owl:Class	
GO:0048738	biolink:NamedThing	cardiac muscle tissue development	The process whose specific outcome is the progression of cardiac muscle over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl	heart muscle development													biological_process											owl:Class	
GO:1904732	biolink:NamedThing	regulation of electron transfer activity	Any process that modulates the frequency, rate or extent of electron transfer activity.	tmpzr1t_l9r_go_relaxed.owl	regulation of bacterial-type ferredoxin|regulation of chloroplast-type ferredoxin|regulation of dicluster bacterial-type ferredoxin|regulation of electron acceptor activity|regulation of small blue copper electron carrier|regulation of electron transfer flavoprotein|regulation of rubredoxin|regulation of high-potential iron-sulfur carrier|regulation of electron transporter activity|regulation of amicyanin|regulation of electron transfer flavoprotein, group I|regulation of adrenodoxin-type ferredoxin|regulation of redox-active disulfide bond electron carrier|regulation of polyferredoxin|regulation of thioredoxin-like 2Fe-2S ferredoxin|regulation of mononuclear iron electron carrier|regulation of copper electron carrier|regulation of monocluster bacterial-type ferredoxin|regulation of 2Fe-2S electron transfer carrier|regulation of iron-sulfur electron transfer carrier|regulation of electron donor activity|regulation of electron transfer flavoprotein, group II|regulation of 3Fe-4S/4Fe-4S electron transfer carrier|regulation of azurin|regulation of electron carrier, chlorophyll electron transport system							lb	2015-10-15T07:51:19Z					biological_process											owl:Class	
GO:0003402	biolink:NamedThing	planar cell polarity pathway involved in axis elongation	The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal to modulate cytoskeletal elements and control cell polarity that contributes to axis elongation.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-12-21T01:22:11Z					biological_process											owl:Class	
GO:0060681	biolink:NamedThing	branch elongation involved in ureteric bud branching	The growth of a branch of the ureteric bud along its axis.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-06-02T02:52:55Z					biological_process											owl:Class	
GO:0036419	biolink:NamedThing	integral component of mycolate outer membrane	The component of the mycolate outer membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.	tmpzr1t_l9r_go_relaxed.owl	integral to MOM|integral to mycolate outer membrane|integral to mycomembrane							bf	2013-09-05T20:20:04Z					cellular_component											owl:Class	
GO:0036407	biolink:NamedThing	mycolate outer membrane	A mycolic acid-rich cell outer membrane containing a lipid bilayer and long-chain mycolic acids (hydroxylated branched-chain fatty acids) that are covalently linked to the cell wall peptidoglycan via an arabinogalactan network. Found in mycobacteria and related genera (e.g. corynebacteria).	tmpzr1t_l9r_go_relaxed.owl	mycobacterial outer membrane|MOM|mycomembrane							bf	2013-08-15T13:33:46Z					cellular_component											owl:Class	
GO:2000267	biolink:NamedThing	negative regulation of blood coagulation, intrinsic pathway	Any process that stops, prevents or reduces the frequency, rate or extent of blood coagulation, intrinsic pathway.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-11-23T11:45:46Z					biological_process											owl:Class	
GO:0007597	biolink:NamedThing	blood coagulation, intrinsic pathway	A protein activation cascade that contributes to blood coagulation and consists of the interactions among high molecular weight kininogen, prekallikrein, and factor XII that lead to the activation of clotting factor X.	tmpzr1t_l9r_go_relaxed.owl						See also the biological process term 'blood coagulation, extrinsic pathway ; GO:0007598'.								biological_process											owl:Class	
GO:1901449	biolink:NamedThing	negative regulation of response to butan-1-ol	Any process that stops, prevents or reduces the frequency, rate or extent of response to butan-1-ol.	tmpzr1t_l9r_go_relaxed.owl	inhibition of response to butan-1-ol|down-regulation of response to butan-1-ol|downregulation of response to butan-1-ol|down regulation of response to butan-1-ol							tt	2012-10-02T14:16:59Z					biological_process											owl:Class	
GO:1901422	biolink:NamedThing	response to butan-1-ol	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a butan-1-ol stimulus.	tmpzr1t_l9r_go_relaxed.owl	process resulting in tolerance to butan-1-ol											GO:1990336		biological_process											owl:Class	
GO:0010798	biolink:NamedThing	regulation of multivesicular body size involved in ubiquitin-dependent protein catabolism	Any process that modulates the volume of a multivesicular body as part of the chemical reactions and pathways resulting in the breakdown of a protein or peptide covalently tagged with ubiquitin.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0006511	biolink:NamedThing	ubiquitin-dependent protein catabolic process	The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of a ubiquitin group, or multiple ubiquitin groups, to the protein.	tmpzr1t_l9r_go_relaxed.owl	myofibrillar protein ubiquitination during ubiquitin-dependent protein catabolism|ubiquitin-dependent protein catabolism|myofibrillar protein ubiquitination during ubiquitin-dependent protein catabolic process|protein ubiquitylation during ubiquitin-dependent protein catabolic process|myofibrillar protein ubiquitination during ubiquitin-dependent protein degradation|protein ubiquitination during ubiquitin-dependent protein catabolic process|protein ubiquitination during ubiquitin-dependent protein degradation|protein ubiquitylation during ubiquitin-dependent protein catabolism|ubiquitin-dependent protein breakdown|protein ubiquitinylation during ubiquitin-dependent protein catabolic process|myofibrillar protein ubiquitination during ubiquitin-dependent protein breakdown|protein ubiquitination during ubiquitin-dependent protein breakdown|protein ubiquitinylation during ubiquitin-dependent protein catabolism|protein degradation tagging activity|protein ubiquitination involved in ubiquitin-dependent protein catabolic process|ubiquitin-dependent protein degradation|ubiquitin-dependent proteolysis|protein ubiquitination during ubiquitin-dependent protein catabolism											GO:0042787|GO:0043432		biological_process											owl:Class	
GO:0070745	biolink:NamedThing	interleukin-35 complex	A protein complex that is composed of an interleukin-12 alpha subunit (p35, product of the IL12A gene) and an EBI3 subunit and is secreted into the extracellular space.	tmpzr1t_l9r_go_relaxed.owl	p35|IL12A|IL-35 complex|EBI3					Note that this heterodimeric cytokine utilizes the same IL-12p35 subunit as its alpha chain as IL-12 uses and the same EBI3 subunit (product of EBI3, Epstein-Barr virus induced gene 3) as its beta chain as IL-27 uses. IL-35 requires both subunits -- there is no separate IL35 gene.		mah	2009-06-23T01:13:14Z					cellular_component											owl:Class	
GO:0001070	biolink:NamedThing	RNA-binding transcription regulator activity	A transcription regulator activity that modulates the transcription of specific gene sets via selective and non-covalent binding to a specific RNA sequence. This function is known to occur in phages and viruses, for example the lambda N and the HIV tat proteins are necessary to allow RNA polymerase to read through terminator sequences.	tmpzr1t_l9r_go_relaxed.owl	RNA binding transcription regulator activity|RNA binding transcription factor activity	https://github.com/geneontology/go-ontology/issues/14872						krc	2010-10-21T04:19:17Z					molecular_function											owl:Class	
GO:0010710	biolink:NamedThing	regulation of collagen catabolic process	Any process that modulates the rate, frequency or extent of collagen catabolism. Collagen catabolism is the proteolytic chemical reactions and pathways resulting in the breakdown of collagen in the extracellular matrix.	tmpzr1t_l9r_go_relaxed.owl	regulation of collagen breakdown|regulation of collagen degradation|regulation of collagen catabolism													biological_process											owl:Class	
GO:0030574	biolink:NamedThing	collagen catabolic process	The proteolytic chemical reactions and pathways resulting in the breakdown of collagen in the extracellular matrix, usually carried out by proteases secreted by nearby cells.	tmpzr1t_l9r_go_relaxed.owl	collagen catabolism|collagen degradation|collagen breakdown													biological_process											owl:Class	
GO:0106060	biolink:NamedThing	regulation of exit from meiosis	Any process that modulates the frequency, rate or extent of exit from mitosis.	tmpzr1t_l9r_go_relaxed.owl								hjd	2017-10-18T16:48:01Z					biological_process											owl:Class	
GO:0045066	biolink:NamedThing	regulatory T cell differentiation	The process in which a relatively unspecialized T cell acquires specialized features of a regulatory T cell. Regulatory T cells control or suppress immune responses through a variety of mechanisms and subsets include the CD4+CD25+ cell type as well as certain CD8+ cell types.	tmpzr1t_l9r_go_relaxed.owl	suppressor T lymphocyte differentiation|suppressor T-lymphocyte differentiation|regulatory T cell development|suppressor T-cell differentiation|regulatory T-cell differentiation|suppressor T cell differentiation|regulatory T-lymphocyte differentiation|regulatory T lymphocyte differentiation					Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.								biological_process											owl:Class	
GO:0035004	biolink:NamedThing	phosphatidylinositol 3-kinase activity	Catalysis of the reaction: ATP + a phosphatidylinositol = ADP + a phosphatidylinositol 3-phosphate. This reaction is the addition of a phosphate group to phosphatidylinositol or one of its phosphorylated derivatives at the 3' position of the inositol ring.	tmpzr1t_l9r_go_relaxed.owl	phosphoinositide 3-kinase activity				Reactome:R-HSA-9028519|Reactome:R-HSA-9670433|Reactome:R-HSA-2045911|Reactome:R-HSA-1433514|Wikipedia:Phosphoinositide_3-kinase									molecular_function											owl:Class	
GO:1900731	biolink:NamedThing	positive regulation of adenylate cyclase-inhibiting opioid receptor signaling pathway	Any process that activates or increases the frequency, rate or extent of adenylate cyclase-inhibiting opioid receptor signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	activation of opioid receptor-mediated adenylate cyclase inhibition|upregulation of adenylate cyclase-inhibiting opioid receptor signaling pathway|activation of adenylate cyclase-inhibiting opioid receptor signaling pathway|up regulation of adenylate cyclase-inhibiting opioid receptor signaling pathway							bf	2012-05-25T03:21:19Z					biological_process											owl:Class	
GO:0031635	biolink:NamedThing	adenylate cyclase-inhibiting opioid receptor signaling pathway	The series of molecular signals generated as a consequence of an opioid receptor binding to its physiological ligand, where the pathway proceeds with inhibition of adenylyl cyclase and a subsequent decrease in the concentration of cyclic AMP (cAMP).	tmpzr1t_l9r_go_relaxed.owl	inhibition of adenylate cyclase activity by opioid receptor signaling pathway|opioid receptor, adenylate cyclase inhibiting pathway|inhibition of adenylate cyclase activity by opioid receptor signalling pathway													biological_process											owl:Class	
GO:1902047	biolink:NamedThing	polyamine transmembrane transport	The process in which a polyamine macromolecule is transported across a membrane.	tmpzr1t_l9r_go_relaxed.owl	polyamine import|polyamine uptake							tb	2013-04-03T15:34:57Z			GO:1905122		biological_process											owl:Class	
GO:0005759	biolink:NamedThing	mitochondrial matrix	The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation.	tmpzr1t_l9r_go_relaxed.owl	mitochondrial lumen|mitochondrial stroma				NIF_Subcellular:sao1804523077|Wikipedia:Mitochondrial_matrix							GO:0031980		cellular_component											owl:Class	
GO:0032461	biolink:NamedThing	positive regulation of protein oligomerization	Any process that activates or increases the frequency, rate or extent of protein oligomerization.	tmpzr1t_l9r_go_relaxed.owl	activation of protein oligomerization|up regulation of protein oligomerization|upregulation of protein oligomerization|induction of protein oligomerization|stimulation of protein oligomerization|up-regulation of protein oligomerization													biological_process											owl:Class	
GO:0007301	biolink:NamedThing	female germline ring canal formation	Assembly of the intercellular bridges that connect the germ-line cells of a female cyst.	tmpzr1t_l9r_go_relaxed.owl	nurse cell ring canal formation|ovarian ring canal formation													biological_process											owl:Class	
GO:0021666	biolink:NamedThing	rhombomere 5 formation	The process that gives rise to rhombomere 5. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0001938	biolink:NamedThing	positive regulation of endothelial cell proliferation	Any process that activates or increases the rate or extent of endothelial cell proliferation.	tmpzr1t_l9r_go_relaxed.owl	upregulation of endothelial cell proliferation|up-regulation of endothelial cell proliferation|stimulation of endothelial cell proliferation|up regulation of endothelial cell proliferation|activation of endothelial cell proliferation													biological_process											owl:Class	
GO:0050934	biolink:NamedThing	late stripe melanocyte differentiation	The process in which a relatively unspecialized cell acquires the specialized features of a late stripe melanocyte (LSM). In zebrafish, LSMs develop during the second phase (3-4 weeks of development) of the larva-to-adult transition (2-4 weeks of development).	tmpzr1t_l9r_go_relaxed.owl	late stripe melanocyte cell differentiation|late stripe melanophore differentiation													biological_process											owl:Class	
GO:0022416	biolink:NamedThing	chaeta development	The process whose specific outcome is the progression of a chaeta over time, from its formation to the mature structure. A chaeta is a sensory multicellular cuticular outgrowth of a specifically differentiated cell.	tmpzr1t_l9r_go_relaxed.owl	bristle development													biological_process											owl:Class	
GO:0004340	biolink:NamedThing	glucokinase activity	Catalysis of the reaction: ATP + D-glucose = ADP + D-glucose-6-phosphate.	tmpzr1t_l9r_go_relaxed.owl	glucokinase (phosphorylating)|glucose kinase activity|ATP:D-glucose 6-phosphotransferase activity				MetaCyc:GLUCOKIN-RXN|EC:2.7.1.2|Reactome:R-HSA-5621918|Reactome:R-HSA-70420|Reactome:R-HSA-5621888|RHEA:17825									molecular_function											owl:Class	
GO:0140104	biolink:NamedThing	molecular carrier activity	Directly binding to a specific ion or molecule and delivering it either to an acceptor molecule or to a specific location.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/20848|https://github.com/geneontology/go-ontology/issues/14221				Note that a carrier moves with its substrate/cargo, while a transporter does not move with the cargo, but facilitates the change in localization.		pg	2017-09-19T13:10:18Z					molecular_function											owl:Class	
GO:0080155	biolink:NamedThing	regulation of double fertilization forming a zygote and endosperm	Any process that modulates the rate, frequency or extent of double fertilization forming a zygote and endosperm. Double fertilization forming a zygote and endosperm is a type of fertilization where one of the two sperm nuclei from the pollen tube fuses with the egg nucleus to form a 2n zygote, and the other fuses with the two polar nuclei to form the 3n primary endosperm nucleus and then develops into the endosperm. The ploidy level of the 2n zygote and 3n primary endosperm nucleus is determined by the ploidy level of the parents involved. An example of this component is found in Arabidopsis thaliana.	tmpzr1t_l9r_go_relaxed.owl								dhl	2010-09-01T03:46:39Z					biological_process											owl:Class	
GO:0009567	biolink:NamedThing	double fertilization forming a zygote and endosperm	Fertilization where one of the two sperm nuclei from the pollen tube fuses with the egg nucleus to form a 2n zygote, and the other fuses with the two polar nuclei to form the 3n primary endosperm nucleus and then develops into the endosperm. The ploidy level of the 2n zygote and 3n primary endosperm nucleus is determined by the ploidy level of the parents involved. An example of this component is found in Arabidopsis thaliana.	tmpzr1t_l9r_go_relaxed.owl	double fertilization													biological_process											owl:Class	
GO:0022405	biolink:NamedThing	hair cycle process	A multicellular organismal process involved in the cyclical phases of growth (anagen), regression (catagen), quiescence (telogen), and shedding (exogen) in the life of a hair; one of the collection or mass of filaments growing from the skin of an animal, and forming a covering for a part of the head or for any part or the whole of the body.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0042633	biolink:NamedThing	hair cycle	The cyclical phases of growth (anagen), regression (catagen), quiescence (telogen), and shedding (exogen) in the life of a hair; one of the collection or mass of filaments growing from the skin of an animal, and forming a covering for a part of the head or for any part or the whole of the body.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0034743	biolink:NamedThing	APC-IQGAP complex	A protein complex that contains the tumor suppressor protein adenomatous polyposis coli (APC) and the Rac1 and Cdc42 effector IQGAP1; may play a role in cytoskeleton organization and cell migration.	tmpzr1t_l9r_go_relaxed.owl						Note that the gene/protein name 'APC' should not be confused with the abbreviation for 'anaphase promoting complex'.								cellular_component											owl:Class	
GO:0031252	biolink:NamedThing	cell leading edge	The area of a motile cell closest to the direction of movement.	tmpzr1t_l9r_go_relaxed.owl	leading edge of cell|front of cell													cellular_component											owl:Class	
GO:0019071	biolink:NamedThing	viral DNA cleavage involved in viral genome maturation	The cleavage of viral DNA into singular functional units.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0019070	biolink:NamedThing	viral genome maturation	The processes involved in creating a mature, stable viral genome. Begins after genome replication with a newly synthesized nucleic acid and ends when the genome is ready to be packaged. Includes the addition of proteins to the newly synthesized genome, and DNA repair processes.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0021637	biolink:NamedThing	trigeminal nerve structural organization	The process that contributes to the act of creating the structural organization of the oculomotor nerve. This process pertains to the physical shaping of a rudimentary structure. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains sensory branches that reach the pterygopalatine fossa via the inferior orbital fissure (face, cheek and upper teeth) and pterygopalatine canal (soft and hard palate, nasal cavity and pharynx). The motor part of the mandibular branch is distributed to the muscles of mastication, the mylohyoid muscle and the anterior belly of the digastric. The mandibular nerve also innervates the tensor veli palatini and tensor tympani muscles. The sensory part of the mandibular nerve is composed of branches that carry general sensory information from the mucous membranes of the mouth and cheek, anterior two-thirds of the tongue, lower teeth, skin of the lower jaw, side of the head and scalp and meninges of the anterior and middle cranial fossae.	tmpzr1t_l9r_go_relaxed.owl	CN V structural organization|trigeminal nerve structural organisation													biological_process											owl:Class	
GO:2000063	biolink:NamedThing	positive regulation of ureter smooth muscle cell differentiation	Any process that activates or increases the frequency, rate or extent of ureter smooth muscle cell differentiation.	tmpzr1t_l9r_go_relaxed.owl								jl	2010-08-20T01:44:28Z					biological_process											owl:Class	
GO:0072193	biolink:NamedThing	ureter smooth muscle cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell in the ureter.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-03-01T01:55:01Z					biological_process											owl:Class	
GO:0062201	biolink:NamedThing	actin wave	A cellular anatomical entity that is part of the actin cytoskeleton and results in a wave-like propagation of actin networks. It consists of dynamic structures traveling on the ventral (substrate-attached) side of the cell during cell migration, cytokinesis, adhesion and neurogenesis.	tmpzr1t_l9r_go_relaxed.owl								dph	2020-01-02T13:45:03Z					cellular_component											owl:Class	
GO:0072212	biolink:NamedThing	regulation of transcription from RNA polymerase II promoter involved in metanephros development	Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the branching morphogenesis by which the metanephros progresses from its initial formation to the mature state.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-03-18T01:14:09Z					biological_process											owl:Class	
GO:1903839	biolink:NamedThing	positive regulation of mRNA 3'-UTR binding	Any process that activates or increases the frequency, rate or extent of mRNA 3'-UTR binding.	tmpzr1t_l9r_go_relaxed.owl	up regulation of mRNA 3' UTR binding|positive regulation of mRNA 3' UTR binding|upregulation of mRNA 3'-UTR binding|up-regulation of mRNA 3'-UTR binding|activation of mRNA 3'-UTR binding|upregulation of mRNA 3' UTR binding|up regulation of mRNA 3'-UTR binding|activation of mRNA 3' UTR binding|up-regulation of mRNA 3' UTR binding							als	2015-01-22T11:54:17Z					biological_process											owl:Class	
GO:1900641	biolink:NamedThing	negative regulation of austinol biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of austinol biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of austinol anabolism|inhibition of austinol biosynthetic process|down regulation of austinol biosynthesis|downregulation of austinol biosynthetic process|down regulation of austinol formation|negative regulation of austinol biosynthesis|downregulation of austinol formation|down regulation of austinol synthesis|negative regulation of austinol anabolism|inhibition of austinol anabolism|downregulation of austinol anabolism|down-regulation of austinol synthesis|downregulation of austinol biosynthesis|down regulation of austinol anabolism|inhibition of austinol formation|negative regulation of austinol formation|down regulation of austinol biosynthetic process|down-regulation of austinol formation|down-regulation of austinol biosynthetic process|negative regulation of austinol synthesis|inhibition of austinol synthesis|downregulation of austinol synthesis|inhibition of austinol biosynthesis|down-regulation of austinol biosynthesis							di	2012-05-22T03:57:59Z					biological_process											owl:Class	
GO:1900560	biolink:NamedThing	austinol biosynthetic process	The chemical reactions and pathways resulting in the formation of austinol.	tmpzr1t_l9r_go_relaxed.owl	austinol anabolism|austinol synthesis|austinol formation|austinol biosynthesis							di	2012-05-15T06:27:30Z					biological_process											owl:Class	
GO:2000813	biolink:NamedThing	negative regulation of barbed-end actin filament capping	Any process that stops, prevents or reduces the frequency, rate or extent of barbed-end actin filament capping.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of plus-end F-actin capping activity|negative regulation of plus-end actin filament capping activity|negative regulation of barbed-end actin capping activity|negative regulation of barbed-end F-actin capping activity							rl	2011-07-07T04:08:18Z					biological_process											owl:Class	
GO:0051016	biolink:NamedThing	barbed-end actin filament capping	The binding of a protein or protein complex to the barbed (or plus) end of an actin filament, thus preventing the addition, exchange or removal of further actin subunits.	tmpzr1t_l9r_go_relaxed.owl	plus-end actin filament capping activity|barbed-end actin capping activity|barbed-end F-actin capping activity|plus-end F-actin capping activity													biological_process											owl:Class	
GO:0043282	biolink:NamedThing	pharyngeal muscle development	The process whose specific outcome is the progression of the pharyngeal muscle over time, from its formation to the mature structure. A pharyngeal muscle is any muscle that forms part of the pharynx.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0060465	biolink:NamedThing	pharynx development	The biological process whose specific outcome is the progression of a pharynx from an initial condition to its mature state. The pharynx is the part of the digestive system immediately posterior to the mouth.	tmpzr1t_l9r_go_relaxed.owl	pharyngeal development													biological_process											owl:Class	
GO:0035761	biolink:NamedThing	dorsal motor nucleus of vagus nerve maturation	A developmental process, independent of morphogenetic (shape) change, that is required for the dorsal motor nucleus of the vagus nerve to attain its fully functional state.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-03-29T02:45:50Z					biological_process											owl:Class	
GO:2000859	biolink:NamedThing	negative regulation of aldosterone secretion	Any process that stops, prevents or reduces the frequency, rate or extent of aldosterone secretion.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-07-26T08:47:31Z					biological_process											owl:Class	
GO:1905804	biolink:NamedThing	positive regulation of cellular response to manganese ion	Any process that activates or increases the frequency, rate or extent of cellular response to manganese ion.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of cellular response to manganese ion|up-regulation of cellular response to manganese|activation of cellular response to manganese ion|activation of cellular response to manganese|positive regulation of cellular response to manganese|upregulation of cellular response to manganese|upregulation of cellular response to manganese ion|up regulation of cellular response to manganese ion|up regulation of cellular response to manganese							pga	2017-01-11T14:59:57Z					biological_process											owl:Class	
GO:0071287	biolink:NamedThing	cellular response to manganese ion	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a manganese ion stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to manganese							mah	2009-12-10T04:06:18Z					biological_process											owl:Class	
GO:0046976	biolink:NamedThing	histone methyltransferase activity (H3-K27 specific)	Catalysis of the reaction: S-adenosyl-L-methionine + histone H3 L-lysine (position 27) = S-adenosyl-L-homocysteine + histone H3 N6-methyl-L-lysine (position 27). This reaction is the addition of a methyl group onto lysine at position 27 of the histone H3 protein.	tmpzr1t_l9r_go_relaxed.owl	histone methylase activity (H3-K27 specific)|histone lysine N-methyltransferase activity (H3-K27 specific)				Reactome:R-HSA-3240295									molecular_function											owl:Class	
GO:0070734	biolink:NamedThing	histone H3-K27 methylation	The modification of histone H3 by addition of one or more methyl groups to lysine at position 27 of the histone.	tmpzr1t_l9r_go_relaxed.owl	histone lysine H3 K27 methylation|histone H3 K27 methylation|histone H3K27me							mah	2009-06-19T11:44:37Z					biological_process											owl:Class	
GO:1905052	biolink:NamedThing	negative regulation of base-excision repair	Any process that stops, prevents or reduces the frequency, rate or extent of base-excision repair.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of base-excision repair|inhibition of BER|downregulation of BER|negative regulation of BER|down regulation of BER|inhibition of base-excision repair|downregulation of base-excision repair|down-regulation of BER|down regulation of base-excision repair							ah	2016-03-16T10:52:09Z					biological_process											owl:Class	
GO:0140014	biolink:NamedThing	mitotic nuclear division	A mitotic cell cycle process comprising the steps by which the nucleus of a eukaryotic cell divides; the process involves condensation of chromosomal DNA into a highly compacted form. Canonically, mitosis produces two daughter nuclei whose chromosome complement is identical to that of the mother cell.	tmpzr1t_l9r_go_relaxed.owl	mitosis	https://github.com/geneontology/go-ontology/issues/19910						pg	2017-03-23T14:44:23Z					biological_process											owl:Class	
GO:0015436	biolink:NamedThing	ABC-type capsular-polysaccharide transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + capsular polysaccharide(in) = ADP + phosphate + capsular polysaccharide(out).	tmpzr1t_l9r_go_relaxed.owl	ATPase-coupled capsular-polysaccharide transporter activity|capsular-polysaccharide-transporting ATPase activity|ATP-dependent capsular-polysaccharide transporter activity|capsular-polysaccharide ABC transporter|ATP phosphohydrolase (capsular-polysaccharide-exporting)				EC:7.6.2.12|MetaCyc:3.6.3.38-RXN									molecular_function											owl:Class	
GO:0015776	biolink:NamedThing	capsular polysaccharide transport	The directed movement of capsular polysaccharides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Capsular polysaccharides make up the capsule, a protective structure surrounding some species of bacteria and fungi.	tmpzr1t_l9r_go_relaxed.owl	capsular-polysaccharide transport|capsule polysaccharide transport													biological_process											owl:Class	
GO:0045655	biolink:NamedThing	regulation of monocyte differentiation	Any process that modulates the frequency, rate or extent of monocyte differentiation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0030224	biolink:NamedThing	monocyte differentiation	The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of a monocyte.	tmpzr1t_l9r_go_relaxed.owl	monocyte cell differentiation													biological_process											owl:Class	
GO:1904362	biolink:NamedThing	regulation of calcitonin secretion	Any process that modulates the frequency, rate or extent of calcitonin secretion.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-06-15T17:54:52Z					biological_process											owl:Class	
GO:0036161	biolink:NamedThing	calcitonin secretion	The regulated release of calcitonin, a peptide hormone that participates in calcium and phosphorus metabolism, from a cell.	tmpzr1t_l9r_go_relaxed.owl								bf	2012-03-26T01:30:32Z					biological_process											owl:Class	
GO:0072316	biolink:NamedThing	alpha-glucan catabolic process involved in ascospore release from ascus	The chemical reactions and pathways resulting in the breakdown of alpha-glucans in the ascus wall that contributes to the release of ascospores from the ascus.	tmpzr1t_l9r_go_relaxed.owl	alpha-glucan breakdown involved in ascospore release from ascus|alpha-glucan catabolism involved in ascospore release from ascus|alpha-glucan degradation involved in ascospore release from ascus							mah	2010-10-25T05:43:52Z					biological_process											owl:Class	
GO:0048735	biolink:NamedThing	haltere morphogenesis	The process in which the anatomical structures of a haltere are generated and organized.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0007482	biolink:NamedThing	haltere development	The process whose specific outcome is the progression of the haltere over time, from its formation to the mature structure. The haltere is the club-shaped 'balancers' found on each side of the metathorax among the true flies (Diptera). They are the much-modified hind wings.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0002783	biolink:NamedThing	antifungal peptide biosynthetic process	The chemical reactions and pathways resulting in the formation of an antifungal peptide.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1903775	biolink:NamedThing	regulation of DNA double-strand break processing	Any process that modulates the frequency, rate or extent of DNA double-strand break processing.	tmpzr1t_l9r_go_relaxed.owl								al	2015-01-06T17:08:15Z					biological_process											owl:Class	
GO:0000729	biolink:NamedThing	DNA double-strand break processing	The 5' to 3' exonucleolytic resection of the DNA at the site of the break to form a 3' single-strand DNA overhang.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0061002	biolink:NamedThing	negative regulation of dendritic spine morphogenesis	Any process that decreases the rate, frequency, or extent of dendritic spine morphogenesis, the process in which the anatomical structures of a dendritic spine are generated and organized. A dendritic spine is a protrusion from a dendrite and a specialized subcellular compartment involved in synaptic transmission.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-01-20T09:34:49Z					biological_process											owl:Class	
GO:0060997	biolink:NamedThing	dendritic spine morphogenesis	The process in which the anatomical structures of a dendritic spine are generated and organized. A dendritic spine is a protrusion from a dendrite and a specialized subcellular compartment involved in synaptic transmission.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-01-20T09:09:57Z					biological_process											owl:Class	
GO:0051878	biolink:NamedThing	lateral element assembly	The cell cycle process in which lateral elements are formed. Axial elements form a proteinaceous core between the two sister chromatids of each chromosome; the two axial elements then connect along their entire lengths by fine fibers known as transverse filaments, forming the lateral elements.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0007130	biolink:NamedThing	synaptonemal complex assembly	The cell cycle process in which the synaptonemal complex is formed. This is a structure that holds paired chromosomes together during prophase I of meiosis and that promotes genetic recombination.	tmpzr1t_l9r_go_relaxed.owl	synaptonemal complex formation													biological_process											owl:Class	
GO:0140648	biolink:NamedThing	positive regulation of cell cycle switching, mitotic to meiotic cell cycle	Any process that activates or increases the frequency, rate or extent of mitotic to meiotic cell cycle switching, the process in which a cell switches cell cycle mode from mitotic to meiotic division.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/21506						pg	2021-05-25T06:18:49Z					biological_process											owl:Class	
GO:0051728	biolink:NamedThing	cell cycle switching, mitotic to meiotic cell cycle	The process in which a cell switches cell cycle mode from mitotic to meiotic division.	tmpzr1t_l9r_go_relaxed.owl	initiation of meiotic cell cycle|cell cycle switching, mitosis to meiosis|conversion to meiotic cell cycle|initiation of meiosis|conversion to meiosis|entry into meiosis|meiotic entry|entry into meiotic cell cycle											GO:0042061		biological_process											owl:Class	
GO:1901305	biolink:NamedThing	negative regulation of spermidine biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of spermidine biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of spermidine biosynthesis|down-regulation of spermidine anabolism|down regulation of spermidine biosynthesis|downregulation of spermidine formation|downregulation of spermidine biosynthetic process|inhibition of spermidine biosynthetic process|inhibition of spermidine formation|downregulation of spermidine biosynthesis|down-regulation of spermidine biosynthetic process|inhibition of spermidine synthesis|downregulation of spermidine synthesis|down regulation of spermidine biosynthetic process|negative regulation of spermidine biosynthesis|negative regulation of spermidine anabolism|down-regulation of spermidine synthesis|inhibition of spermidine anabolism|down regulation of spermidine synthesis|negative regulation of spermidine synthesis|downregulation of spermidine anabolism|down regulation of spermidine anabolism|negative regulation of spermidine formation|inhibition of spermidine biosynthesis|down-regulation of spermidine formation|down regulation of spermidine formation							pm	2012-08-21T13:58:45Z					biological_process											owl:Class	
GO:0008295	biolink:NamedThing	spermidine biosynthetic process	The chemical reactions and pathways resulting in the formation of spermidine, N-(3-aminopropyl)-1,4-diaminobutane.	tmpzr1t_l9r_go_relaxed.owl	spermidine formation|spermidine synthesis|spermidine biosynthesis|spermidine anabolism				MetaCyc:BSUBPOLYAMSYN-PWY|MetaCyc:POLYAMINSYN3-PWY									biological_process											owl:Class	
GO:1904617	biolink:NamedThing	negative regulation of actin binding	Any process that stops, prevents or reduces the frequency, rate or extent of actin binding.	tmpzr1t_l9r_go_relaxed.owl	down regulation of membrane associated actin binding|down-regulation of actin binding|downregulation of membrane associated actin binding|inhibition of actin binding|negative regulation of membrane associated actin binding|down-regulation of membrane associated actin binding|downregulation of actin binding|inhibition of membrane associated actin binding|down regulation of actin binding							mr	2015-08-27T19:09:02Z					biological_process											owl:Class	
GO:0003779	biolink:NamedThing	actin binding	Binding to monomeric or multimeric forms of actin, including actin filaments.	tmpzr1t_l9r_go_relaxed.owl	membrane associated actin binding													molecular_function											owl:Class	
GO:0051102	biolink:NamedThing	DNA ligation involved in DNA recombination	The re-formation of a broken phosphodiester bond in the DNA backbone, carried out by DNA ligase, that contributes to DNA recombination.	tmpzr1t_l9r_go_relaxed.owl	DNA ligation during DNA recombination													biological_process											owl:Class	
GO:0061090	biolink:NamedThing	positive regulation of sequestering of zinc ion	Any process that increases the rate, frequency, or extent of sequestering of zinc ion. Sequestering of zinc ion is the process of binding or confining zinc ions such that they are separated from other components of a biological system.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-04-26T01:38:53Z					biological_process											owl:Class	
GO:0032119	biolink:NamedThing	sequestering of zinc ion	The process of binding or confining zinc ions such that they are separated from other components of a biological system.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1903111	biolink:NamedThing	negative regulation of single-strand break repair via homologous recombination	Any process that stops, prevents or reduces the frequency, rate or extent of single-strand break repair via homologous recombination.	tmpzr1t_l9r_go_relaxed.owl	down regulation of single-strand break repair via homologous recombination|inhibition of single-strand break repair via homologous recombination|downregulation of single-strand break repair via homologous recombination|down-regulation of single-strand break repair via homologous recombination							pr	2014-06-09T12:11:32Z					biological_process											owl:Class	
GO:1990396	biolink:NamedThing	single-strand break repair via homologous recombination	The error-free repair of a single-strand break in DNA in which the broken DNA molecule is repaired using homologous sequences. A strand in the broken DNA searches for a homologous region in an intact chromosome to serve as the template for DNA synthesis. The restoration of two intact DNA molecules results in the exchange, reciprocal or nonreciprocal, of genetic material between the intact DNA molecule and the broken DNA molecule.	tmpzr1t_l9r_go_relaxed.owl								bhm	2014-06-09T10:47:04Z					biological_process											owl:Class	
GO:0097042	biolink:NamedThing	extrinsic component of fungal-type vacuolar membrane	The component of a fungal-type vacuolar membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.	tmpzr1t_l9r_go_relaxed.owl	extrinsic to fungal-type vacuolar membrane							pr	2011-04-19T03:42:39Z					cellular_component											owl:Class	
GO:0002904	biolink:NamedThing	positive regulation of B cell apoptotic process	Any process that activates or increases the frequency, rate, or extent of B cell apoptotic process.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of B cell apoptosis|upregulation of B cell apoptosis|up regulation of B cell apoptosis|stimulation of B cell apoptosis|up-regulation of B cell apoptosis|activation of B cell apoptosis													biological_process											owl:Class	
GO:0001783	biolink:NamedThing	B cell apoptotic process	Any apoptotic process in a B cell, a lymphocyte of B lineage with the phenotype CD19-positive and capable of B cell mediated immunity.	tmpzr1t_l9r_go_relaxed.owl	programmed cell death of B-cells by apoptosis|programmed cell death, B cells|programmed cell death, B-cells|programmed cell death, B-lymphocytes|B lymphocyte apoptosis|B-cell programmed cell death by apoptosis|programmed cell death of B-lymphocytes by apoptosis|B lymphocyte programmed cell death by apoptosis|apoptosis of B-lymphocytes|apoptosis of B-cells|apoptosis of B lymphocytes|apoptosis of B cells|programmed cell death, B lymphocytes|B-cell apoptosis|programmed cell death of B cells by apoptosis|B cell programmed cell death by apoptosis|B cell apoptosis|programmed cell death of B lymphocytes by apoptosis|B-lymphocyte programmed cell death by apoptosis|B-lymphocyte apoptosis													biological_process											owl:Class	
GO:0061800	biolink:NamedThing	fibronectin fibril	A supramolecular fiber formed from fibronectin molecules. The fibrils are 5 to 25nm in diameter and can form branched meshworks.	tmpzr1t_l9r_go_relaxed.owl								dph	2016-10-24T14:04:21Z					cellular_component											owl:Class	
GO:0031904	biolink:NamedThing	endosome lumen	The volume enclosed by the membrane of an endosome.	tmpzr1t_l9r_go_relaxed.owl					NIF_Subcellular:sao1547508851									cellular_component											owl:Class	
GO:0008917	biolink:NamedThing	lipopolysaccharide N-acetylglucosaminyltransferase activity	Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + lipopolysaccharide = UDP + N-acetyl-D-glucosaminyl-lipopolysaccharide.	tmpzr1t_l9r_go_relaxed.owl	uridine diphosphoacetylglucosamine-lipopolysaccharide acetylglucosaminyltransferase activity|LPS N-acetylglucosaminyltransferase activity|UDP-N-acetylglucosamine-lipopolysaccharide N-acetylglucosaminyltransferase activity|UDP-N-acetyl-D-glucosamine:lipopolysaccharide N-acetyl-D-glucosaminyltransferase activity				MetaCyc:2.4.1.56-RXN|EC:2.4.1.56									molecular_function											owl:Class	
GO:0086099	biolink:NamedThing	phospholipase C-activating angiotensin-activated signaling pathway involved in heart process	An angiotensin-mediated signaling pathway that contributes to a circulatory system process carried out by the heart, where the activated receptor transmits the signal via Gq-mediated activation of phospholipase C (PLC). PLC hydrolyses phosphatidylinositol 4,5-bisphosphate (PIP2) into the second messengers inositol-1,4,5,-triphosphate (IP3) and diacylglycerol (DAG). DAG activates protein kinase C (PKC), whilst IP3 binds intracellular receptors to induce the release of Ca2+ from intracellular stores.	tmpzr1t_l9r_go_relaxed.owl	PLC-activating angiotensin receptor signaling pathway involved in heart process|Gq-coupled angiotensin receptor signaling pathway involved in heart process|angiotensin receptor signaling pathway via activation of phospholipase C involved in heart process|phospholipase C-activating angiotensin-mediated signaling pathway involved in heart process|cardiac angiotensin receptor signaling pathway via activation of PLC							bf						biological_process											owl:Class	
GO:1990751	biolink:NamedThing	Schwann cell chemotaxis	The directed movement of a Schwann cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).	tmpzr1t_l9r_go_relaxed.owl								sl	2015-05-21T19:19:09Z					biological_process											owl:Class	
GO:0060126	biolink:NamedThing	somatotropin secreting cell differentiation	The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a somatotropin secreting cell. A somatotropin secreting cell is an acidophilic cell of the anterior pituitary that produces growth hormone, somatotropin.	tmpzr1t_l9r_go_relaxed.owl	somatotrophin secreting cell differentiation|somatotroph differentiation|somatrophic cell differentiation|somatotrope differentiation|growth hormone secreting cell differentiation|somatotropic cell differentiation													biological_process											owl:Class	
GO:0048525	biolink:NamedThing	negative regulation of viral process	Any process that stops, prevents, or reduces the frequency, rate or extent of a multi-organism process in which a virus is a participant.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of viral reproduction|negative regulation of viral life cycle|down-regulation of viral life cycle|down regulation of viral life cycle|downregulation of viral life cycle|inhibition of viral life cycle													biological_process											owl:Class	
GO:0061061	biolink:NamedThing	muscle structure development	The progression of a muscle structure over time, from its formation to its mature state. Muscle structures are contractile cells, tissues or organs that are found in multicellular organisms.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-03-09T08:55:14Z					biological_process											owl:Class	
GO:2000871	biolink:NamedThing	negative regulation of progesterone secretion	Any process that stops, prevents or reduces the frequency, rate or extent of progesterone secretion.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-07-26T08:51:19Z					biological_process											owl:Class	
GO:0050832	biolink:NamedThing	defense response to fungus	Reactions triggered in response to the presence of a fungus that act to protect the cell or organism.	tmpzr1t_l9r_go_relaxed.owl	resistance response to pathogenic fungus|response to parasitic fungus|defence response to fungus|defense response to fungus, incompatible interaction|defense response to fungi|resistance response to pathogenic fungi|defence response to fungi|response to parasitic fungi											GO:0009817|GO:0009623|GO:0042831		biological_process											owl:Class	
GO:0010133	biolink:NamedThing	proline catabolic process to glutamate	The chemical reactions and pathways resulting in the breakdown of proline into other compounds, including glutamate.	tmpzr1t_l9r_go_relaxed.owl	proline degradation to glutamate|proline oxidation|proline breakdown to glutamate				MetaCyc:PWY-4561|MetaCyc:PROUT-PWY							GO:0019494		biological_process											owl:Class	
GO:0070716	biolink:NamedThing	mismatch repair involved in maintenance of fidelity involved in DNA-dependent DNA replication	A mismatch repair process that corrects errors introduced that ensures the accuracy of DNA replication.	tmpzr1t_l9r_go_relaxed.owl	mismatch repair involved in maintenance of fidelity during DNA-dependent DNA replication							mah	2009-06-09T04:00:29Z					biological_process											owl:Class	
GO:0045956	biolink:NamedThing	positive regulation of calcium ion-dependent exocytosis	Any process that activates or increases the frequency, rate or extent of calcium ion-dependent exocytosis.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of calcium ion-dependent exocytosis|stimulation of calcium ion-dependent exocytosis|up regulation of calcium ion-dependent exocytosis|activation of calcium ion-dependent exocytosis|upregulation of calcium ion-dependent exocytosis													biological_process											owl:Class	
GO:0062094	biolink:NamedThing	stomach development	The process whose specific outcome is the progression of the stomach over time, from its formation to the mature structure. The stomach is an expanded region of the vertebrate alimentary tract that serves as a food storage compartment and digestive organ.	tmpzr1t_l9r_go_relaxed.owl								dph	2018-11-20T18:15:45Z					biological_process											owl:Class	
GO:0000457	biolink:NamedThing	endonucleolytic cleavage between SSU-rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 5S)	Endonucleolytic cleavage to separate a pre-SSU-rRNA from a pre-LSU-rRNA originally produced as a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, the Large Subunit (LSU) rRNA, and the 5S rRNA, in that order, from 5' to 3' along the primary transcript. Note that the use of the word tricistronic refers only to the number of mature rRNA molecules which will be produced from the primary transcript and ignores tRNAs that may also be present within the primary transcript.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:2000481	biolink:NamedThing	positive regulation of cAMP-dependent protein kinase activity	Any process that activates or increases the frequency, rate or extent of cAMP-dependent protein kinase activity.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of cAMP-dependent protein kinase, intrinsic catalyst activity|positive regulation of cyclic AMP-dependent protein kinase activity|positive regulation of 3',5'-cAMP-dependent protein kinase activity|positive regulation of PKA|positive regulation of adenosine 3',5'-cyclophosphate-dependent protein kinase activity|positive regulation of PKA C|positive regulation of AMPK|positive regulation of 3',5' cAMP-dependent protein kinase activity|positive regulation of STK22|positive regulation of ATP:protein phosphotransferase (cAMP-dependent) activity|positive regulation of protein kinase A activity							yaf	2011-03-10T11:14:17Z					biological_process											owl:Class	
GO:0019962	biolink:NamedThing	type I interferon binding	Binding to a type I interferon. Type I interferons include the interferon-alpha, beta, delta, epsilon, zeta, kappa, tau, and omega gene families.	tmpzr1t_l9r_go_relaxed.owl	interferon-zeta binding|interferon-alpha binding|interferon-beta binding|interferon-alpha/beta binding|interferon-omega binding|interferon-tau binding|type I IFN binding|interferon-kappa binding|interferon-epsilon binding|interferon-delta binding													molecular_function											owl:Class	
GO:0006509	biolink:NamedThing	membrane protein ectodomain proteolysis	The proteolytic cleavage of transmembrane proteins and release of their ectodomain (extracellular domain).	tmpzr1t_l9r_go_relaxed.owl	ectoderm shedding|receptor shedding|ectodomain cleavage|membrane protein solubilization													biological_process											owl:Class	
GO:1902796	biolink:NamedThing	regulation of snoRNA processing	Any process that modulates the frequency, rate or extent of snoRNA processing.	tmpzr1t_l9r_go_relaxed.owl								mah	2014-03-24T12:47:02Z					biological_process											owl:Class	
GO:0043144	biolink:NamedThing	sno(s)RNA processing	Any process involved in the conversion of a primary snoRNA family RNA transcript into a mature snoRNA (eukaryota) or sRNA (archaea).	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/20416												biological_process											owl:Class	
GO:1901343	biolink:NamedThing	negative regulation of vasculature development	Any process that stops, prevents or reduces the frequency, rate or extent of vasculature development.	tmpzr1t_l9r_go_relaxed.owl	inhibition of vasculature development|downregulation of vasculature development|inhibition of vascular system development|down regulation of vasculature development|downregulation of vascular system development|down-regulation of vasculature development|down-regulation of vascular system development|negative regulation of vascular system development|down regulation of vascular system development							bf	2012-09-06T09:17:24Z					biological_process											owl:Class	
GO:0043248	biolink:NamedThing	proteasome assembly	The aggregation, arrangement and bonding together of a mature, active proteasome complex.	tmpzr1t_l9r_go_relaxed.owl	proteasome complex assembly|proteasome maturation|26S proteasome assembly													biological_process											owl:Class	
GO:0043253	biolink:NamedThing	chloroplast ribosome	A ribosome contained within a chloroplast.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0038180	biolink:NamedThing	nerve growth factor signaling pathway	A series of molecular signals initiated by the binding of nerve growth factor (NGF) to a receptor on the surface of the target cell, and ending with regulation of a downstream cellular process, e.g. transcription.	tmpzr1t_l9r_go_relaxed.owl	NGF signaling pathway|nerve growth factor signalling pathway				Wikipedia:Nerve_growth_factor	Nerve growth factor (NGF) binds at least two classes of receptors: the p75 LNGFR (low-affinity nerve growth factor receptor) and TrkA, a transmembrane tyrosine kinase.		bf	2013-05-15T11:04:05Z					biological_process											owl:Class	
GO:1990090	biolink:NamedThing	cellular response to nerve growth factor stimulus	A process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nerve growth factor stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to NGF							sl	2013-05-06T17:13:36Z					biological_process											owl:Class	
GO:0150047	biolink:NamedThing	G protein-coupled neurotransmitter receptor activity involved in regulation of presynaptic membrane potential	G protein-coupled neurotransmitter receptor activity, occurring in the presynaptic membrane, involved in regulation of presynaptic membrane potential.	tmpzr1t_l9r_go_relaxed.owl	G-protein coupled neurotransmitter receptor activity involved in regulation of presynaptic membrane potential							bc	2018-04-23T10:51:20Z					molecular_function											owl:Class	
GO:0099505	biolink:NamedThing	regulation of presynaptic membrane potential	Any process that modulates the potential difference across a presynaptic membrane.	tmpzr1t_l9r_go_relaxed.owl	regulation of pre-synaptic membrane potential													biological_process											owl:Class	
GO:0005894	biolink:NamedThing	interleukin-3 receptor complex	A protein complex that binds interleukin-3; comprises an alpha and a beta subunit. The alpha chain is specific to the interleukin-3 receptor, whereas the beta chain is shared with the receptors for granulocyte-macrophage colony-stimulating factor and interleukin-5.	tmpzr1t_l9r_go_relaxed.owl	IL-3 receptor complex													cellular_component											owl:Class	
GO:1903132	biolink:NamedThing	regulation of tube lumen cavitation	Any process that modulates the frequency, rate or extent of tube lumen cavitation.	tmpzr1t_l9r_go_relaxed.owl								dph	2014-06-25T20:18:58Z					biological_process											owl:Class	
GO:0060605	biolink:NamedThing	tube lumen cavitation	The formation of a lumen by hollowing out a solid rod or cord.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-05-15T09:39:49Z					biological_process											owl:Class	
GO:0021803	biolink:NamedThing	extension of leading cell process to pial surface	The extension of a long process to the pial surface as a cell leaves the ventricular zone.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0021802	biolink:NamedThing	somal translocation	The radial migration of cells from the ventricular zone that is independent of radial glial cells. Cells extend processes that terminate at the pial surface and follow the processes as they migrate.	tmpzr1t_l9r_go_relaxed.owl	perikaryal translocation of Morest													biological_process											owl:Class	
GO:0007569	biolink:NamedThing	cell aging	An aging process that has as participant a cell after a cell has stopped dividing. Cell aging may occur when a cell has temporarily stopped dividing through cell cycle arrest (GO:0007050) or when a cell has permanently stopped dividing, in which case it is undergoing cellular senescence (GO:0090398). May precede cell death (GO:0008219) and succeed cell maturation (GO:0048469).	tmpzr1t_l9r_go_relaxed.owl	cell ageing													biological_process											owl:Class	
GO:0034117	biolink:NamedThing	erythrocyte aggregation	The adhesion of one erythrocyte to one or more other erythrocytes via adhesion molecules.	tmpzr1t_l9r_go_relaxed.owl	RBC aggregation|red blood cell aggregation													biological_process											owl:Class	
GO:0101002	biolink:NamedThing	ficolin-1-rich granule	Highly exocytosable gelatinase-poor granules found in neutrophils and rich in ficolin-1.  Ficolin-1 is released from neutrophil granules by stimulation with fMLP or PMA, and the majority becomes associated with the surface membrane of the cells and can be detected by flow cytometry.	tmpzr1t_l9r_go_relaxed.owl	ficolin-1 rich granule|ficolin granule													cellular_component											owl:Class	
GO:0002469	biolink:NamedThing	myeloid dendritic cell antigen processing and presentation	The process in which a myeloid dendritic cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0015932	biolink:NamedThing	nucleobase-containing compound transmembrane transporter activity	Enables the transfer of nucleobases, nucleosides, nucleotides and nucleic acids from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	nucleobase, nucleoside, nucleotide and nucleic acid transmembrane transporter activity													molecular_function											owl:Class	
GO:0072309	biolink:NamedThing	mesenchymal stem cell maintenance involved in metanephric nephron morphogenesis	The process in which an organism retains a population of mesenchymal stem cells that contributes to the shaping of a nephron in the metanephros. A mesenchymal stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-04-09T05:03:41Z					biological_process											owl:Class	
GO:0031135	biolink:NamedThing	negative regulation of conjugation	Any process that decreases the rate of conjugation.	tmpzr1t_l9r_go_relaxed.owl	inhibition of conjugation|downregulation of conjugation|down-regulation of conjugation|down regulation of conjugation													biological_process											owl:Class	
GO:0061936	biolink:NamedThing	fusion of sperm to egg plasma membrane involved in double fertilization forming a zygote and endosperm	The binding and fusion of a sperm, with the plasma membrane of the oocyte as part of the process of double fertilization forming a zygote and endosperm.	tmpzr1t_l9r_go_relaxed.owl								dph	2017-09-05T18:43:24Z					biological_process											owl:Class	
GO:0002278	biolink:NamedThing	eosinophil activation involved in immune response	The change in morphology and behavior of a eosinophil resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response.	tmpzr1t_l9r_go_relaxed.owl	eosinophil activation during immune response													biological_process											owl:Class	
GO:1904092	biolink:NamedThing	regulation of autophagic cell death	Any process that modulates the frequency, rate or extent of autophagic cell death.	tmpzr1t_l9r_go_relaxed.owl	regulation of programmed cell death by autophagy|regulation of programmed cell death by macroautophagy|regulation of autophagic death|regulation of type II programmed cell death							bhm	2015-03-26T16:41:32Z					biological_process											owl:Class	
GO:0048102	biolink:NamedThing	autophagic cell death	A form of programmed cell death that is accompanied by the formation of autophagosomes. Autophagic cell death is characterized by lack of chromatin condensation and massive vacuolization of the cytoplasm, with little or no uptake by phagocytic cells.	tmpzr1t_l9r_go_relaxed.owl	autosis|autophagic death|type II programmed cell death|programmed cell death by autophagy|programmed cell death by macroautophagy					The precise nature of autophagic cell death is still being debated, and the link between autophagy and cell death unclear. As autophagy is often induced under conditions of stress that could also lead to cell death, there has been a propagation of the idea that autophagy can act as a cell death mechanism; but others suggest that autophagy may simply be an attempt of dying cells to adapt to lethal stress rather than a mechanism to execute a cell death program. Further studies are required to resolve this controversy (see e.g. PMID:22082964, PMID:22052193, PMID:25236395). In the meantime, curators should carefully examine the experimental evidence presented in papers concerning autophagic cell death, and annotate accordingly. Recently, an instance of autophagic cell death, termed autosis, was discovered that relies on the plasma membrane Na+/K+-ATPase. Autosis was observed in vivo in the brain of rats subjected to an ischemic insult. It's still unclear if all cases of autophagic cell death require the Na+/K+-ATPase or not.								biological_process											owl:Class	
GO:0071700	biolink:NamedThing	olfactory placode maturation	A developmental process, independent of morphogenetic (shape) change, that is required for the olfactory placode to attain its fully functional state. The olfactory placode is a thickening of the neural ectoderm in the head region of the vertebrate embryo which develops into the olfactory region of the nasal cavity.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-03-02T01:10:54Z					biological_process											owl:Class	
GO:0071698	biolink:NamedThing	olfactory placode development	The progression of the olfactory placode over time from its initial formation until its mature state. The olfactory placode is a thickening of the neural ectoderm in the head region of the vertebrate embryo which develops into the olfactory region of the nasal cavity.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-03-02T12:45:14Z					biological_process											owl:Class	
GO:0032112	biolink:NamedThing	negative regulation of protein histidine kinase activity	Any process that stops, prevents, or reduces the frequency, rate or extent of protein histidine kinase activity.	tmpzr1t_l9r_go_relaxed.owl	downregulation of protein histidine kinase activity|protein histidine kinase inhibitor|down-regulation of protein histidine kinase activity|inhibition of protein histidine kinase activity|down regulation of protein histidine kinase activity													biological_process											owl:Class	
GO:0002737	biolink:NamedThing	negative regulation of plasmacytoid dendritic cell cytokine production	Any process that stops, prevents, or reduces the frequency, rate, or extent of plasmacytoid dendritic cell cytokine production.	tmpzr1t_l9r_go_relaxed.owl	downregulation of plasmacytoid dendritic cell cytokine production|down-regulation of plasmacytoid dendritic cell cytokine production|inhibition of plasmacytoid dendritic cell cytokine production|down regulation of plasmacytoid dendritic cell cytokine production													biological_process											owl:Class	
GO:0002373	biolink:NamedThing	plasmacytoid dendritic cell cytokine production	Any process that contributes to cytokine production by a plasmacytoid dendritic cell.	tmpzr1t_l9r_go_relaxed.owl						Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.								biological_process											owl:Class	
GO:0055026	biolink:NamedThing	negative regulation of cardiac muscle tissue development	Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle tissue development.	tmpzr1t_l9r_go_relaxed.owl	downregulation of cardiac muscle development|negative regulation of heart muscle development|inhibition of cardiac muscle development|down regulation of cardiac muscle development|down-regulation of cardiac muscle development													biological_process											owl:Class	
GO:2000947	biolink:NamedThing	positive regulation of amylopectin catabolic process	Any process that activates or increases the frequency, rate or extent of amylopectin catabolic process.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of Amylopectin catabolism							tt	2011-08-01T02:15:32Z					biological_process											owl:Class	
GO:2000897	biolink:NamedThing	amylopectin catabolic process	The chemical reactions and pathways resulting in the breakdown of an amylopectin.	tmpzr1t_l9r_go_relaxed.owl	Amylopectin catabolism							jl	2011-07-28T02:47:28Z					biological_process											owl:Class	
GO:0010615	biolink:NamedThing	positive regulation of cardiac muscle adaptation	Any process that increases the rate, extent or frequency of the process in which cardiac muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0045010	biolink:NamedThing	actin nucleation	The initial step in the formation of an actin filament, in which actin monomers combine to form a new filament. Nucleation is slow relative to the subsequent addition of more monomers to extend the filament.	tmpzr1t_l9r_go_relaxed.owl	actin filament nucleation	https://github.com/geneontology/go-ontology/issues/20313												biological_process											owl:Class	
GO:0030184	biolink:NamedThing	nitric oxide transmembrane transporter activity	Enables the transfer of nitric oxide, nitrogen monoxide, from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0030185	biolink:NamedThing	nitric oxide transport	The directed movement of nitric oxide, nitrogen monoxide, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0010606	biolink:NamedThing	positive regulation of cytoplasmic mRNA processing body assembly	Any process that increases the rate, frequency, or extent of the aggregation, arrangement and bonding together of proteins and RNA molecules to form a cytoplasmic mRNA processing body.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0033962	biolink:NamedThing	P-body assembly	The aggregation, arrangement and bonding together of proteins and RNA molecules to form a cytoplasmic mRNA processing body.	tmpzr1t_l9r_go_relaxed.owl	cytoplasmic mRNA processing body assembly|P body assembly|P body biogenesis	https://github.com/geneontology/go-ontology/issues/19857												biological_process											owl:Class	
GO:0035463	biolink:NamedThing	transforming growth factor beta receptor signaling pathway involved in determination of left/right asymmetry	A series of molecular signals initiated by the binding of an extracellular ligand to a transforming growth factor beta receptor on the surface of a target cell, which contributes to determination of organismal asymmetry with respect to the left and right halves.	tmpzr1t_l9r_go_relaxed.owl	TGFbeta receptor signaling pathway involved in determination of left/right asymmetry|TGF-beta receptor signaling pathway involved in determination of left/right asymmetry|transforming growth factor beta receptor signalling pathway involved in determination of left/right asymmetry|TGFbeta receptor signalling pathway involved in determination of left/right asymmetry|TGF-beta receptor signalling pathway involved in determination of left/right asymmetry							bf	2010-04-19T01:19:20Z					biological_process											owl:Class	
GO:1900572	biolink:NamedThing	diorcinol biosynthetic process	The chemical reactions and pathways resulting in the formation of diorcinol.	tmpzr1t_l9r_go_relaxed.owl	diorcinol formation|diorcinol biosynthesis|diorcinol synthesis|diorcinol anabolism							di	2012-05-15T06:35:29Z					biological_process											owl:Class	
GO:2000120	biolink:NamedThing	positive regulation of sodium-dependent phosphate transport	Any process that activates or increases the frequency, rate or extent of sodium-dependent phosphate transport.	tmpzr1t_l9r_go_relaxed.owl								jl	2010-09-23T01:35:06Z					biological_process											owl:Class	
GO:0044341	biolink:NamedThing	sodium-dependent phosphate transport	The directed movement of phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore, by a mechanism dependent upon sodium ions.	tmpzr1t_l9r_go_relaxed.owl								jl	2010-08-20T04:16:15Z					biological_process											owl:Class	
GO:0097399	biolink:NamedThing	interleukin-32-mediated signaling pathway	A series of molecular signals initiated by the binding of interleukin-32 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.	tmpzr1t_l9r_go_relaxed.owl	interleukin-32-mediated signalling pathway|IL-32-mediated signalling pathway|IL-32-mediated signaling pathway							pr	2012-10-23T13:27:22Z					biological_process											owl:Class	
GO:0097397	biolink:NamedThing	cellular response to interleukin-32	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-32 stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to IL-32							pr	2012-10-23T13:23:22Z					biological_process											owl:Class	
GO:0033700	biolink:NamedThing	phospholipid efflux	The directed movement of a phospholipid out of a cell or organelle.	tmpzr1t_l9r_go_relaxed.owl	phospholipid export													biological_process											owl:Class	
GO:0036398	biolink:NamedThing	TCR signalosome	A multi-protein complex containing at least the T-cell receptor complex and the LAT (linker for activation of T cells) scaffold protein. Also contains a variety of signaling proteins including co-receptors, kinases, phosphatases and adaptors such as CD8. Connects events on the plasma membrane to distal signaling cascades to ultimately modulate T cell biology.	tmpzr1t_l9r_go_relaxed.owl	LAT signalosome|linker for activation of T cells signalosome							bf	2013-07-18T13:52:24Z					cellular_component											owl:Class	
GO:1900534	biolink:NamedThing	palmitic acid catabolic process	The chemical reactions and pathways resulting in the breakdown of palmitic acid.	tmpzr1t_l9r_go_relaxed.owl								tb	2012-05-09T07:04:56Z					biological_process											owl:Class	
GO:0150143	biolink:NamedThing	regulation of CD80 production	Any process that modulates the frequency, rate or extent of CD80 biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of CD80 biosynthetic process							bc	2019-12-08T10:23:43Z					biological_process											owl:Class	
GO:0035780	biolink:NamedThing	CD80 biosynthetic process	The chemical reactions and pathways resulting in the formation of CD80, a CD marker that occurs on antigen presenting cells such as activated B cells and monocytes that provides a co-stimulatory signal necessary for T cell activation and survival.	tmpzr1t_l9r_go_relaxed.owl	CD80 anabolism|CD80 formation|CD80 synthesis|CD80 biosynthesis							bf	2011-04-04T11:18:41Z					biological_process											owl:Class	
GO:1990900	biolink:NamedThing	ciliary pocket collar	A constriction site at the junction of the plasma, flagellar and flagellar pocket membranes where the flagellum emerges from the cell body. Observed in some unicellular eukaryotic species such as Chlamydomonas, Giardia and Trypanosoma.	tmpzr1t_l9r_go_relaxed.owl	flagellum pocket collar|cilium pocket collar|flagellar pocket collar|flagellar pore|FPC|flagellar collar					Note that a 'flagellar collar' is described in Choanoflagellates, but this is different from the ciliary pocket collar found e.g. in Giardia; in Choanoflagellates, a single apical flagellum is surrounded by a collar of 30-40 microvilli.		pr	2015-11-17T14:43:55Z					cellular_component											owl:Class	
GO:0020016	biolink:NamedThing	ciliary pocket	Invagination of the plasma membrane from which a cilium (also called flagellum) protrudes.	tmpzr1t_l9r_go_relaxed.owl	cilial pocket|cilium pocket|flagellar pocket					Note that cilia and eukaryotic flagella are deemed to be equivalent. In this case community usage is mostly 'flagellar', but the primary term name reflects the cilium parentage.								cellular_component											owl:Class	
GO:1903007	biolink:NamedThing	positive regulation of Lys63-specific deubiquitinase activity	Any process that activates or increases the frequency, rate or extent of Lys63-specific deubiquitinase activity.	tmpzr1t_l9r_go_relaxed.owl	up regulation of Lys63-specific deubiquitinase activity|activation of Lys63-specific deubiquitinase activity|up-regulation of Lys63-specific deubiquitinase activity|upregulation of Lys63-specific deubiquitinase activity							bf	2014-05-12T15:47:35Z					biological_process											owl:Class	
GO:0061578	biolink:NamedThing	Lys63-specific deubiquitinase activity	Hydrolysis of Lys63-Linked ubiquitin unit(s) from a ubiquitinated protein.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-5696547|Reactome:R-HSA-5691431|Reactome:R-HSA-5357845|Reactome:R-HSA-936381|Reactome:R-HSA-5690856|Reactome:R-HSA-5691411|Reactome:R-HSA-936390|Reactome:R-HSA-8869506|Reactome:R-HSA-688136|Reactome:R-HSA-741411|Reactome:R-HSA-5691439			dph	2013-11-15T19:13:12Z					molecular_function											owl:Class	
GO:0015568	biolink:NamedThing	L-idonate transmembrane transporter activity	Enables the transfer of L-idonate from one side of a membrane to the other. L-idonate is an aldonic acid derived from L-idose, an aldohexose which is epimeric with D-glucose.	tmpzr1t_l9r_go_relaxed.owl	L-idonate/D-gluconate:hydrogen symporter activity													molecular_function											owl:Class	
GO:0015726	biolink:NamedThing	L-idonate transmembrane transport	The process in which L-idonate is transported across a lipid bilayer, from one side of a membrane to the other. L-idonate is an aldonic acid derived from L-idose, an aldohexose which is epimeric with D-glucose.	tmpzr1t_l9r_go_relaxed.owl	L-idonate transport													biological_process											owl:Class	
GO:0051651	biolink:NamedThing	maintenance of location in cell	Any process in which a substance or cellular entity, such as a protein complex or organelle, is maintained in a specific location within, or in the membrane of, a cell, and is prevented from moving elsewhere.	tmpzr1t_l9r_go_relaxed.owl	cellular storage|cellular retention|intracellular sequestering|intracellular retention|maintenance of localization within cell|intracellular storage|maintenance of localization in cell|sequestering within cell|maintenance of cellular localization|cellular sequestering|maintenance of intracellular localization|storage within cell|retention within cell													biological_process											owl:Class	
GO:0048889	biolink:NamedThing	neuromast support cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a neuromast support cell. Support cells are non-sensory cells of the neuromast that extend between the sensory hair cells from the basement membrane to the apical surface; they are surrounded by mantle cells.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0035393	biolink:NamedThing	chemokine (C-X-C motif) ligand 9 production	The appearance of chemokine (C-X-C motif) ligand 9 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	tmpzr1t_l9r_go_relaxed.owl	CXCL9 production|Monokine induced by gamma interferon production|MIG production							bf	2010-03-23T10:03:20Z					biological_process											owl:Class	
GO:0071639	biolink:NamedThing	positive regulation of monocyte chemotactic protein-1 production	Any process that activates or increases the frequency, rate, or extent of production of monocyte chemotactic protein-1.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of MCP-1 production|positive regulation of CCL2 production							mah	2010-02-12T10:39:51Z					biological_process											owl:Class	
GO:0071605	biolink:NamedThing	monocyte chemotactic protein-1 production	The appearance of monocyte chemotactic protein-1 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	tmpzr1t_l9r_go_relaxed.owl	MCP-1 production|CCL2 production							mah	2010-02-05T04:09:53Z					biological_process											owl:Class	
GO:0048232	biolink:NamedThing	male gamete generation	Generation of the male gamete; specialised haploid cells produced by meiosis and along with a female gamete takes part in sexual reproduction.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0001655	biolink:NamedThing	urogenital system development	The process whose specific outcome is the progression of the urogenital system over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0002514	biolink:NamedThing	B cell tolerance induction	A process involving any mechanism for tolerance induction in B cells.	tmpzr1t_l9r_go_relaxed.owl	B-lymphocyte tolerance induction|B lymphocyte tolerance induction|B-cell tolerance induction													biological_process											owl:Class	
GO:0043045	biolink:NamedThing	DNA methylation involved in embryo development	The covalent transfer of a methyl group to C-5 of cytosine that contributes to the epigenetic regulation of embryonic gene expression.	tmpzr1t_l9r_go_relaxed.owl	de novo DNA methylation													biological_process											owl:Class	
GO:2001254	biolink:NamedThing	negative regulation of histone H3-K36 trimethylation	Any process that stops, prevents or reduces the frequency, rate or extent of histone H3-K36 trimethylation.	tmpzr1t_l9r_go_relaxed.owl								pr	2011-12-06T07:38:17Z					biological_process											owl:Class	
GO:0097198	biolink:NamedThing	histone H3-K36 trimethylation	The modification of histone H3 by addition of three methyl groups to lysine at position 36 of the histone.	tmpzr1t_l9r_go_relaxed.owl								pr	2011-12-05T01:19:45Z					biological_process											owl:Class	
GO:0043931	biolink:NamedThing	ossification involved in bone maturation	The formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone, involved in the progression of the skeleton from its formation to its mature state.	tmpzr1t_l9r_go_relaxed.owl	ossification involved in skeletal development|ossification involved in bone modeling													biological_process											owl:Class	
GO:0002760	biolink:NamedThing	positive regulation of antimicrobial humoral response	Any process that activates or increases the frequency, rate, or extent of an antimicrobial humoral response.	tmpzr1t_l9r_go_relaxed.owl	activation of antimicrobial humoral response|up-regulation of antimicrobial humoral response|stimulation of antimicrobial humoral response|up regulation of antimicrobial humoral response|upregulation of antimicrobial humoral response													biological_process											owl:Class	
GO:0045041	biolink:NamedThing	protein import into mitochondrial intermembrane space	The import of proteins into the space between the inner and outer mitochondrial membranes.	tmpzr1t_l9r_go_relaxed.owl	protein import into mitochondrial IMS|protein import into mitochondrial intermembrane space, nonconservative|protein transport into mitochondrial IMS|protein import into mitochondrial intermembrane space, direct|protein transport into mitochondrial intermembrane space|mitochondrial intermembrane space protein import											GO:0045043|GO:0045044		biological_process											owl:Class	
GO:0072076	biolink:NamedThing	nephrogenic mesenchyme development	The biological process whose specific outcome is the progression of a nephrogenic mesenchyme from an initial condition to its mature state. This process begins with the formation of nephrogenic mesenchyme and ends with the mature structure. Nephrogenic mesenchyme is the tissue made up of loosely connected mesenchymal cells in the nephron.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-01-25T04:40:44Z					biological_process											owl:Class	
GO:0032747	biolink:NamedThing	positive regulation of interleukin-23 production	Any process that activates or increases the frequency, rate, or extent of interleukin-23 production.	tmpzr1t_l9r_go_relaxed.owl	stimulation of interleukin-23 production|upregulation of interleukin-23 production|positive regulation of interleukin-23 biosynthetic process|positive regulation of IL-23 production|up regulation of interleukin-23 production|up-regulation of interleukin-23 production|activation of interleukin-23 production											GO:0045398		biological_process											owl:Class	
GO:0032627	biolink:NamedThing	interleukin-23 production	The appearance of interleukin-23 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	tmpzr1t_l9r_go_relaxed.owl	interleukin-23 secretion|IL-23 production|interleukin-23 biosynthetic process											GO:0072621|GO:0042240		biological_process											owl:Class	
GO:1903238	biolink:NamedThing	positive regulation of leukocyte tethering or rolling	Any process that activates or increases the frequency, rate or extent of leukocyte tethering or rolling.	tmpzr1t_l9r_go_relaxed.owl	activation of leukocyte tethering or rolling|up regulation of leukocyte tethering or rolling|up-regulation of leukocyte tethering or rolling|upregulation of leukocyte tethering or rolling							als	2014-07-31T13:08:01Z					biological_process											owl:Class	
GO:0050901	biolink:NamedThing	leukocyte tethering or rolling	Transient adhesive interactions between leukocytes and endothelial cells lining blood vessels. Carbohydrates on circulating leukocytes bind selectins on the vessel wall causing the leukocytes to slow down and roll along the inner surface of the vessel wall. During this rolling motion, transitory bonds are formed and broken between selectins and their ligands. Typically the first step in cellular extravasation (the movement of leukocytes out of the circulatory system, towards the site of tissue damage or infection).	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/12276#issuecomment-185260139|https://github.com/geneontology/go-ontology/issues/20174												biological_process											owl:Class	
GO:0045804	biolink:NamedThing	negative regulation of eclosion	Any process that stops, prevents, or reduces the frequency, rate or extent of eclosion.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of eclosion|down regulation of eclosion|downregulation of eclosion|inhibition of eclosion													biological_process											owl:Class	
GO:0007562	biolink:NamedThing	eclosion	The emergence of an adult insect from a pupa case.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Pupa#Emergence									biological_process											owl:Class	
GO:0071805	biolink:NamedThing	potassium ion transmembrane transport	A process in which a potassium ion is transported from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	potassium ion membrane transport|high affinity potassium ion uptake|high-affinity potassium ion uptake|high-affinity potassium ion import|high affinity potassium ion import					Note that this term is not intended for use in annotating lateral movement within membranes.		mah	2010-09-03T02:43:49Z			GO:0010163		biological_process											owl:Class	
GO:1900484	biolink:NamedThing	negative regulation of protein targeting to vacuolar membrane	Any process that stops, prevents or reduces the frequency, rate or extent of protein targeting to vacuolar membrane.	tmpzr1t_l9r_go_relaxed.owl	downregulation of protein targeting to vacuolar membrane|down-regulation of protein targeting to vacuolar membrane|down regulation of protein targeting to vacuolar membrane|inhibition of protein targeting to vacuolar membrane							al	2012-05-02T10:13:33Z					biological_process											owl:Class	
GO:0044395	biolink:NamedThing	protein targeting to vacuolar membrane	The process of directing proteins towards the vacuolar membrane; usually uses signals contained within the protein.	tmpzr1t_l9r_go_relaxed.owl								jl	2011-12-21T02:54:44Z					biological_process											owl:Class	
GO:1905744	biolink:NamedThing	regulation of mRNA cis splicing, via spliceosome	Any process that modulates the frequency, rate or extent of mRNA cis splicing, via spliceosome.	tmpzr1t_l9r_go_relaxed.owl	regulation of nuclear mRNA cis splicing, via U2-type spliceosome|regulation of nuclear mRNA cis splicing, via spliceosome|regulation of splicing							vw	2016-12-07T14:01:33Z					biological_process											owl:Class	
GO:0045292	biolink:NamedThing	mRNA cis splicing, via spliceosome	The joining together, after removal of an intervening sequence composed of one or more introns, of two segments of the same RNA molecule via spliceosomal catalysis to produce an mRNA composed only of exon sequences that all came from the same primary transcript.	tmpzr1t_l9r_go_relaxed.owl	splicing|nuclear mRNA cis splicing, via spliceosome|nuclear mRNA cis splicing, via U2-type spliceosome													biological_process											owl:Class	
GO:1905221	biolink:NamedThing	positive regulation of platelet formation	Any process that activates or increases the frequency, rate or extent of platelet formation.	tmpzr1t_l9r_go_relaxed.owl	activation of platelet formation|up-regulation of platelet extrusion|up-regulation of platelet formation|positive regulation of platelet extrusion|up regulation of platelet extrusion|activation of platelet extrusion|up regulation of platelet formation|upregulation of platelet extrusion|upregulation of platelet formation							sl	2016-06-06T22:16:02Z					biological_process											owl:Class	
GO:0030220	biolink:NamedThing	platelet formation	The process in which platelets bud from long processes extended by megakaryocytes.	tmpzr1t_l9r_go_relaxed.owl	platelet extrusion													biological_process											owl:Class	
GO:0010784	biolink:NamedThing	proboscis morphogenesis, clypeo-labral disc-derived	The process in which the anatomical structures of the proboscis that are derived from the clypeo-labral disc are generated and organized.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1905434	biolink:NamedThing	positive regulation of retrograde trans-synaptic signaling by neuropeptide	Any process that activates or increases the frequency, rate or extent of retrograde trans-synaptic signaling by neuropeptide.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of retrograde trans-synaptic signaling by neuropeptide|up regulation of retrograde trans-synaptic signaling by neuropeptide|positive regulation of neuropeptide-mediated retrograde trans-synaptic signaling|upregulation of retrograde trans-synaptic signaling by neuropeptide|activation of retrograde trans-synaptic signaling by neuropeptide							bf	2016-09-14T10:57:02Z					biological_process											owl:Class	
GO:0099082	biolink:NamedThing	retrograde trans-synaptic signaling by neuropeptide	Cell-cell signaling from postsynapse to presynapse, across the synaptic cleft, mediated by a neuropeptide.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0007004	biolink:NamedThing	telomere maintenance via telomerase	The maintenance of proper telomeric length by the addition of telomeric repeats by telomerase.	tmpzr1t_l9r_go_relaxed.owl	telomerase-dependent telomere maintenance													biological_process											owl:Class	
GO:0042110	biolink:NamedThing	T cell activation	The change in morphology and behavior of a mature or immature T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.	tmpzr1t_l9r_go_relaxed.owl	T-cell activation|T-lymphocyte activation|T lymphocyte activation													biological_process											owl:Class	
GO:0008009	biolink:NamedThing	chemokine activity	The function of a family of small chemotactic cytokines; their name is derived from their ability to induce directed chemotaxis in nearby responsive cells. All chemokines possess a number of conserved cysteine residues involved in intramolecular disulfide bond formation. Some chemokines are considered pro-inflammatory and can be induced during an immune response to recruit cells of the immune system to a site of infection, while others are considered homeostatic and are involved in controlling the migration of cells during normal processes of tissue maintenance or development. Chemokines are found in all vertebrates, some viruses and some bacteria.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0060326	biolink:NamedThing	cell chemotaxis	The directed movement of a motile cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0031967	biolink:NamedThing	organelle envelope	A double membrane structure enclosing an organelle, including two lipid bilayers and the region between them. In some cases, an organelle envelope may have more than two membranes.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:1904521	biolink:NamedThing	negative regulation of myofibroblast cell apoptotic process	Any process that stops, prevents or reduces the frequency, rate or extent of myofibroblast cell apoptotic process.	tmpzr1t_l9r_go_relaxed.owl	inhibition of MFB apoptosis|down regulation of myofibroblast cell apoptotic process|down regulation of MFB apoptosis|negative regulation of myofibroblast cell apoptosis|negative regulation of MFB apoptotic process|down-regulation of myofibroblast cell apoptotic process|downregulation of myofibroblast cell apoptotic process|inhibition of myofibroblast cell apoptotic process|down-regulation of MFB apoptotic process|downregulation of myofibroblast cell apoptosis|down regulation of myofibroblast cell apoptosis|downregulation of MFB apoptotic process|down-regulation of myofibroblast cell apoptosis|inhibition of MFB apoptotic process|inhibition of myofibroblast cell apoptosis|down-regulation of MFB apoptosis|negative regulation of MFB apoptosis|downregulation of MFB apoptosis|down regulation of MFB apoptotic process							sl	2015-07-29T15:52:20Z					biological_process											owl:Class	
GO:0075041	biolink:NamedThing	positive regulation of establishment of turgor in appressorium	Any process that activates or increases the frequency, rate or extent of turgor formation in the symbiont appressorium.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0150155	biolink:NamedThing	interleukin-34 production	The appearance of interleukin-34 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	tmpzr1t_l9r_go_relaxed.owl								bc	2020-01-06T16:25:25Z					biological_process											owl:Class	
GO:0030094	biolink:NamedThing	plasma membrane-derived photosystem I	A protein complex located in the plasma membrane-derived thylakoid. The photosystem functions as a light-dependent plastocyanin-ferredoxin oxidoreductase, transferring electrons from plastocyanin to ferredoxin. Examples of this complex are found in bacterial species.	tmpzr1t_l9r_go_relaxed.owl	plasma membrane photosystem I													cellular_component											owl:Class	
GO:0061236	biolink:NamedThing	mesonephric comma-shaped body morphogenesis	The process in which the mesonephric comma-shaped body is generated and organized. The mesonephric comma-shaped body is the precursor structure to the mesonephric S-shaped body that contributes to the morphogenesis of a nephron in the mesonephros.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-08-19T03:00:21Z					biological_process											owl:Class	
GO:0003016	biolink:NamedThing	respiratory system process	A process carried out by the organs or tissues of the respiratory system. The respiratory system is an organ system responsible for respiratory gaseous exchange.	tmpzr1t_l9r_go_relaxed.owl	respiratory gaseous exchange											GO:0010802		biological_process											owl:Class	
GO:0043598	biolink:NamedThing	cytoplasmic DNA replication factor C complex	A cytoplasmic complex of two polypeptides that loads the DNA polymerase processivity factor proliferating cell nuclear antigen (PCNA) onto DNA, thereby permitting processive DNA synthesis catalyzed by DNA polymerase. Examples of this component are found in prokaryotic species.	tmpzr1t_l9r_go_relaxed.owl	cytoplasmic RFC|cytoplasmic clamp loader													cellular_component											owl:Class	
GO:0030981	biolink:NamedThing	cortical microtubule cytoskeleton	The portion of the microtubule cytoskeleton that lies just beneath the plasma membrane.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0060263	biolink:NamedThing	regulation of respiratory burst	Any process that modulates the rate frequency or extent of a phase of elevated metabolic activity, during which oxygen consumption increases; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1902845	biolink:NamedThing	negative regulation of mitotic spindle elongation	Any process that stops, prevents or reduces the frequency, rate or extent of mitotic spindle elongation.	tmpzr1t_l9r_go_relaxed.owl	down regulation of mitotic spindle elongation|downregulation of mitotic spindle elongation|negative regulation of spindle elongation during mitosis|downregulation of spindle elongation during mitosis|down regulation of spindle elongation during mitosis|down-regulation of mitotic spindle elongation|down-regulation of spindle elongation during mitosis|inhibition of mitotic spindle elongation|inhibition of spindle elongation during mitosis							vw	2014-04-02T08:43:28Z					biological_process											owl:Class	
GO:0002296	biolink:NamedThing	T-helper 1 cell lineage commitment	The process in which a CD4-positive, alpha-beta T cell becomes committed to becoming a T-helper 1 cell, a CD4-positive, alpha-beta T cell specialized to promote immunological processes often associated with resistance to intracellular bacteria, fungi, and protozoa, and pathological conditions such as arthritis.	tmpzr1t_l9r_go_relaxed.owl	T-helper 1 cell fate commitment|Th1 cell lineage commitment|Th1 fate commitment													biological_process											owl:Class	
GO:0043404	biolink:NamedThing	corticotropin-releasing hormone receptor activity	Combining with corticotropin-releasing hormone and transmitting the signal to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	CRF receptor activity|corticotropin-releasing factor receptor activity|adrenocorticotropin-releasing hormone receptor activity|CRH receptor activity											GO:0031636		molecular_function											owl:Class	
GO:1903912	biolink:NamedThing	negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation	Any process that stops, prevents or reduces the frequency, rate or extent of endoplasmic reticulum stress-induced eiF2alpha phosphorylation.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of eiF2alpha phosphorylation in response to endoplasmic reticulum stress|down-regulation of regulation of translation initiation by eiF2alpha phosphorylation in response to endoplasmic reticulum stress|negative regulation of regulation of translation initiation by eiF2alpha phosphorylation in response to endoplasmic reticulum stress|down regulation of eiF2alpha phosphorylation in response to ER stress|inhibition of eiF2alpha phosphorylation in response to ER stress|downregulation of eiF2alpha phosphorylation in response to endoplasmic reticulum stress|inhibition of eiF2alpha phosphorylation in response to endoplasmic reticulum stress|down-regulation of eiF2alpha phosphorylation in response to ER stress|down-regulation of eiF2alpha phosphorylation in response to endoplasmic reticulum stress|negative regulation of ER stress-induced eIF2 alpha phosphorylation|down regulation of regulation of translation initiation by eiF2alpha phosphorylation in response to endoplasmic reticulum stress|inhibition of regulation of translation initiation by eiF2alpha phosphorylation in response to endoplasmic reticulum stress|negative regulation of eiF2alpha phosphorylation in response to ER stress|down regulation of eiF2alpha phosphorylation in response to endoplasmic reticulum stress|downregulation of eiF2alpha phosphorylation in response to ER stress|downregulation of regulation of translation initiation by eiF2alpha phosphorylation in response to endoplasmic reticulum stress							bf	2015-02-09T10:58:55Z					biological_process											owl:Class	
GO:0036492	biolink:NamedThing	eiF2alpha phosphorylation in response to endoplasmic reticulum stress	The addition of a phosphate group on to the translation initiation factor eIF2alpha, as a result of endoplasmic reticulum stress.	tmpzr1t_l9r_go_relaxed.owl	eiF2alpha phosphorylation in response to ER stress|regulation of translation initiation by eiF2alpha phosphorylation in response to endoplasmic reticulum stress							bf	2015-02-05T09:53:21Z					biological_process											owl:Class	
GO:0005859	biolink:NamedThing	muscle myosin complex	A filament of myosin found in a muscle cell of any type.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0101025	biolink:NamedThing	nuclear membrane biogenesis	The process in which a nuclear membrane is synthesized, aggregates, and bonds together.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0071763	biolink:NamedThing	nuclear membrane organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear inner or outer membrane.	tmpzr1t_l9r_go_relaxed.owl	nuclear membrane organisation|nuclear membrane organization and biogenesis							mah	2010-03-29T03:59:35Z					biological_process											owl:Class	
GO:0007398	biolink:NamedThing	ectoderm development	The process whose specific outcome is the progression of the ectoderm over time, from its formation to the mature structure. In animal embryos, the ectoderm is the outer germ layer of the embryo, formed during gastrulation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0038058	biolink:NamedThing	TNFSF11 receptor activity	Combining with a tumor necrosis factor ligand superfamily member 11 (TNFSF11) and transmitting the signal across the cell membrane to initiate a change in cell activity or function.	tmpzr1t_l9r_go_relaxed.owl	tumor necrosis factor ligand superfamily member 11 receptor activity|RANKL receptor activity							bf	2012-01-04T03:31:54Z					molecular_function											owl:Class	
GO:0071847	biolink:NamedThing	TNFSF11-mediated signaling pathway	A series of molecular signals initiated by the binding of tumor necrosis factor ligand superfamily member 11 (TNFSF11) to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.	tmpzr1t_l9r_go_relaxed.owl	RANKL-mediated signaling pathway|tumor necrosis factor superfamily member 11-mediated signaling pathway|TNF-related activation-induced cytokine-mediated signaling pathway|TNFSF11-mediated signalling pathway|receptor activator of nuclear factor kappa-B ligand signaling pathway							mah	2010-09-10T02:22:42Z					biological_process											owl:Class	
GO:0060798	biolink:NamedThing	transforming growth factor beta receptor signaling pathway involved in mesodermal cell fate specification	The series of molecular signals generated as a consequence of a transforming growth factor beta receptor binding to one of its physiological ligands and ultimately resulting in the specification of a mesodermal fate.	tmpzr1t_l9r_go_relaxed.owl	transforming growth factor beta receptor signalling pathway involved in mesodermal cell fate specification							dph	2009-08-06T11:16:11Z					biological_process											owl:Class	
GO:2000786	biolink:NamedThing	positive regulation of autophagosome assembly	Any process that activates or increases the frequency, rate or extent of autophagic vacuole assembly.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of autophagic vacuole formation|positive regulation of autophagic vacuole assembly|positive regulation of autophagosome formation|positive regulation of PAS formation|positive regulation of autophagosome biosynthesis							rl	2011-06-24T11:19:12Z					biological_process											owl:Class	
GO:0071212	biolink:NamedThing	subsynaptic reticulum	An elaborate tubulolamellar membrane system that underlies the postsynaptic cell membrane.	tmpzr1t_l9r_go_relaxed.owl	SSR							mah	2009-12-01T05:05:21Z					cellular_component											owl:Class	
GO:0044544	biolink:NamedThing	envenomation resulting in plasminogen activation in other organism	The process which begins with venom being forced into an organism by the bite or sting of another organism, and ends with the activation of plasminogen into plasmin in the bitten organism. This process includes cleavage at an internal Arg-Val site to form an N-terminal A-chain and C-terminal B-chain held together by a disulfide bond, and can include further proteolytic cleavage events to remove the preactivation peptide.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-03-22T11:54:49Z					biological_process											owl:Class	
GO:2000712	biolink:NamedThing	regulation of maintenance of meiotic sister chromatid cohesion, arms	Any process that modulates the frequency, rate or extent of maintenance of meiotic sister chromatid cohesion along the chromosome arms.	tmpzr1t_l9r_go_relaxed.owl	regulation of maintenance of sister chromatin cohesion along arms at meiosis I|regulation of maintenance of meiotic sister chromatin cohesion along arms							mah	2011-06-01T12:45:35Z					biological_process											owl:Class	
GO:0002071	biolink:NamedThing	glandular epithelial cell maturation	The developmental process, independent of morphogenetic (shape) change, that is required for a glandular epithelial cell to attain its fully functional state. A glandular epithelial cell is a columnar/cuboidal epithelial cell is a cell found in a two dimensional sheet with a free surface exposed to the lumen of a gland.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0036011	biolink:NamedThing	imaginal disc-derived leg segmentation	Division of an imaginal disc-derived leg into a series of semi-repetitive parts or segments. The Drosophila leg, for example, has nine segments, each separated from the next by a flexible joint.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-10-07T04:37:17Z					biological_process											owl:Class	
GO:0007480	biolink:NamedThing	imaginal disc-derived leg morphogenesis	The process in which the anatomical structures of a leg derived from an imaginal disc are generated and organized. A leg is a limb on which an animal walks and stands. An example of this is found in Drosophila melanogaster.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0046696	biolink:NamedThing	lipopolysaccharide receptor complex	A multiprotein complex that consists of at least three proteins, CD14, TLR4, and MD-2, each of which is glycosylated and which functions as a lipopolysaccharide (LPS) receptor that primes the innate immune response against bacterial pathogens.	tmpzr1t_l9r_go_relaxed.owl	LPS receptor complex					Note that this term should not be used to refer to CD14 alone, but the multiprotein receptor complex that it is part of.								cellular_component											owl:Class	
GO:0062228	biolink:NamedThing	negative regulation of adult somatic muscle development	Any process that decreases the rate, frequency or extent of adult somatic muscle development.	tmpzr1t_l9r_go_relaxed.owl								dph	2020-03-16T13:34:38Z					biological_process											owl:Class	
GO:0007527	biolink:NamedThing	adult somatic muscle development	The process whose specific outcome is the progression of the adult somatic muscle over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0033163	biolink:NamedThing	microneme membrane	The lipid bilayer surrounding a microneme.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0006402	biolink:NamedThing	mRNA catabolic process	The chemical reactions and pathways resulting in the breakdown of mRNA, messenger RNA, which is responsible for carrying the coded genetic 'message', transcribed from DNA, to sites of protein assembly at the ribosomes.	tmpzr1t_l9r_go_relaxed.owl	mRNA breakdown|mRNA catabolism|mRNA degradation|mRNA decay													biological_process											owl:Class	
GO:2000084	biolink:NamedThing	regulation of mesenchymal to epithelial transition involved in mesonephros morphogenesis	Any process that modulates the frequency, rate or extent of mesenchymal to epithelial transition involved in mesonephros morphogenesis.	tmpzr1t_l9r_go_relaxed.owl	regulation of mesonephric mesenchyme to epithelial transition							dph	2010-09-03T06:06:41Z					biological_process											owl:Class	
GO:0061261	biolink:NamedThing	mesenchymal to epithelial transition involved in mesonephros morphogenesis	A transition where a mesenchymal cell establishes apical/basolateral polarity, forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the mesonephros.	tmpzr1t_l9r_go_relaxed.owl	mesonephric mesenchyme to epithelial transition							dph	2010-08-30T02:35:15Z					biological_process											owl:Class	
GO:1990625	biolink:NamedThing	negative regulation of cytoplasmic translational initiation in response to stress	Any process that stops, prevents or reduces the rate of cytoplasmic translation initiation as a result of a stimulus indicating the organism is under stress.	tmpzr1t_l9r_go_relaxed.owl								vw	2015-01-31T21:25:56Z					biological_process											owl:Class	
GO:0060934	biolink:NamedThing	His-Purkinje system cell fate commitment	The commitment of cells to His-Purkinje cell fates and their capacity to differentiate into His-Purkinje cells. These cells form the fibers that regulate cardiac muscle contraction in the ventricles.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-09-29T01:17:00Z					biological_process											owl:Class	
GO:0060932	biolink:NamedThing	His-Purkinje system cell differentiation	The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cell of the His-Purkinje system. These cells form the fibers regulate cardiac muscle contraction in the ventricles.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-09-29T01:10:32Z					biological_process											owl:Class	
GO:0035898	biolink:NamedThing	parathyroid hormone secretion	The regulated release of parathyroid hormone into the circulatory system.	tmpzr1t_l9r_go_relaxed.owl	PTH secretion|parathormone secretion|parathyrin secretion							bf	2011-06-22T09:28:54Z					biological_process											owl:Class	
GO:0005836	biolink:NamedThing	fatty-acyl-CoA synthase complex	A protein complex that possesses fatty-acyl-CoA synthase activity.	tmpzr1t_l9r_go_relaxed.owl	fatty acyl CoA synthase complex					Note that fatty acid synthetases of vertebrates and yeast are stable enzyme complexes of multifunctional polypeptide chains, whereas the fatty acid synthetases of plants and E. coli consist of non-associated individual enzymes.								cellular_component											owl:Class	
GO:0045254	biolink:NamedThing	pyruvate dehydrogenase complex	Complex that carries out the oxidative decarboxylation of pyruvate to form acetyl-CoA; comprises subunits possessing three catalytic activities: pyruvate dehydrogenase (E1), dihydrolipoamide S-acetyltransferase (E2), and dihydrolipoamide dehydrogenase (E3).	tmpzr1t_l9r_go_relaxed.owl	dihydrolipoyl dehydrogenase complex|pyruvate dehydrogenase complex (lipoamide)				Wikipedia:Pyruvate_dehydrogenase_complex	Note that this term represents a location and not a function; the activity possessed by this complex is mentioned in the definition for the purpose of describing and distinguishing the complex. The functions of this complex are represented by the molecular function terms 'pyruvate dehydrogenase (lipoamide) activity ; GO:0004739', 'dihydrolipoamide S-acetyltransferase activity ; GO:0004742', and 'dihydrolipoamide dehydrogenase activity ; GO:0004148'.						GO:0009364		cellular_component											owl:Class	
GO:0032083	biolink:NamedThing	negative regulation of type IV site-specific deoxyribonuclease activity	Any process that stops or reduces the rate of type IV restriction endodeoxyribonuclease activity.	tmpzr1t_l9r_go_relaxed.owl	type IV restriction enzyme inhibitor|type IV restriction endodeoxyribonuclease inhibitor|negative regulation of type IV restriction endodeoxyribonuclease activity|downregulation of type IV restriction endodeoxyribonuclease activity|inhibition of type IV restriction endodeoxyribonuclease activity|down-regulation of type IV restriction endodeoxyribonuclease activity|down regulation of type IV restriction endodeoxyribonuclease activity													biological_process											owl:Class	
GO:0032067	biolink:NamedThing	type IV site-specific deoxyribonuclease activity	Catalysis of the endonucleolytic cleavage of DNA in a site specific manner. Cleavage is dependent on the presence of a specific recognition site in the DNA which must be modified (e.g. methylated, hydroxymethylated, glucosyl-hydroxymethylated).	tmpzr1t_l9r_go_relaxed.owl	type IV restriction enzyme activity													molecular_function											owl:Class	
GO:0140239	biolink:NamedThing	postsynaptic endocytosis	A vesicle-mediated transport process in which the postsynapse take up external materials or membrane constituents by the invagination of a small region of the plasma membrane to form a new membrane-bounded vesicle.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/synapse/issues/230				Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.		pg	2018-07-15T07:38:27Z					biological_process											owl:Class	
GO:1901472	biolink:NamedThing	regulation of Golgi calcium ion export	Any process that modulates the frequency, rate or extent of Golgi calcium ion export.	tmpzr1t_l9r_go_relaxed.owl								al	2012-10-03T07:26:03Z					biological_process											owl:Class	
GO:0061454	biolink:NamedThing	release of sequestered calcium ion into cytosol by Golgi	The directed movement of calcium ions (Ca2+) out of the Golgi apparatus into the cytosol.	tmpzr1t_l9r_go_relaxed.owl	Golgi calcium ion export							dph	2012-07-27T02:29:43Z					biological_process											owl:Class	
GO:0042704	biolink:NamedThing	uterine wall breakdown	The sloughing of the endometrium and blood vessels during menstruation that results from a drop in progesterone levels.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0042703	biolink:NamedThing	menstruation	The cyclic, physiologic discharge through the vagina of blood and endometrial tissues from the nonpregnant uterus.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Menstruation	Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase. To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).								biological_process											owl:Class	
GO:1900215	biolink:NamedThing	negative regulation of apoptotic process involved in metanephric collecting duct development	Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic process involved in metanephric collecting duct development.	tmpzr1t_l9r_go_relaxed.owl	downregulation of apoptotic process of metanephric collecting duct development|negative regulation of apoptotic program of metanephric collecting duct development|downregulation of apoptotic process involved in metanephric collecting duct development|down-regulation of type I programmed cell death of metanephric collecting duct development|down regulation of programmed cell death by apoptosis of metanephric collecting duct development|downregulation of signaling (initiator) caspase activity of metanephric collecting duct development|inhibition of apoptotic programmed cell death of metanephric collecting duct development|down regulation of apoptotic process involved in metanephric collecting duct development|inhibition of apoptotic cell death of metanephric collecting duct development|inhibition of apoptotic process involved in metanephric collecting duct development|downregulation of type I programmed cell death of metanephric collecting duct development|inhibition of apoptosis of metanephric collecting duct development|negative regulation of apoptotic cell death of metanephric collecting duct development|down regulation of apoptotic process of metanephric collecting duct development|inhibition of signaling (initiator) caspase activity of metanephric collecting duct development|negative regulation of apoptotic process of metanephric collecting duct development|down regulation of apoptotic program of metanephric collecting duct development|negative regulation of signaling (initiator) caspase activity of metanephric collecting duct development|downregulation of apoptotic programmed cell death of metanephric collecting duct development|down-regulation of apoptotic program of metanephric collecting duct development|inhibition of programmed cell death by apoptosis of metanephric collecting duct development|negative regulation of programmed cell death by apoptosis of metanephric collecting duct development|downregulation of programmed cell death by apoptosis of metanephric collecting duct development|down regulation of apoptotic programmed cell death of metanephric collecting duct development|down-regulation of apoptosis of metanephric collecting duct development|down regulation of apoptosis of metanephric collecting duct development|negative regulation of apoptosis of metanephric collecting duct development|down-regulation of signaling (initiator) caspase activity of metanephric collecting duct development|down regulation of type I programmed cell death of metanephric collecting duct development|inhibition of apoptotic program of metanephric collecting duct development|down regulation of apoptotic cell death of metanephric collecting duct development|down-regulation of apoptotic cell death of metanephric collecting duct development|downregulation of apoptotic program of metanephric collecting duct development|down-regulation of apoptotic process of metanephric collecting duct development|downregulation of apoptotic cell death of metanephric collecting duct development|down-regulation of apoptotic process involved in metanephric collecting duct development|negative regulation of type I programmed cell death of metanephric collecting duct development|inhibition of type I programmed cell death of metanephric collecting duct development|down-regulation of programmed cell death by apoptosis of metanephric collecting duct development|negative regulation of apoptotic programmed cell death of metanephric collecting duct development|down regulation of signaling (initiator) caspase activity of metanephric collecting duct development|downregulation of apoptosis of metanephric collecting duct development|inhibition of apoptotic process of metanephric collecting duct development|down-regulation of apoptotic programmed cell death of metanephric collecting duct development							yaf	2012-03-22T10:53:31Z					biological_process											owl:Class	
GO:1900204	biolink:NamedThing	apoptotic process involved in metanephric collecting duct development	Any apoptotic process that is involved in metanephric collecting duct development.	tmpzr1t_l9r_go_relaxed.owl	apoptotic program of metanephric collecting duct development|signaling (initiator) caspase activity of metanephric collecting duct development|type I programmed cell death of metanephric collecting duct development|apoptotic process of metanephric collecting duct development|apoptotic cell death of metanephric collecting duct development|apoptotic programmed cell death of metanephric collecting duct development|programmed cell death by apoptosis of metanephric collecting duct development|apoptosis of metanephric collecting duct development							yaf	2012-03-21T01:21:32Z					biological_process											owl:Class	
GO:0002339	biolink:NamedThing	B cell selection	The process dependent upon B cell antigen receptor signaling in response to self or foreign antigen through which B cells are selected for survival.	tmpzr1t_l9r_go_relaxed.owl	B lymphocyte selection|B-lymphocyte selection|B-cell selection													biological_process											owl:Class	
GO:0030183	biolink:NamedThing	B cell differentiation	The process in which a precursor cell type acquires the specialized features of a B cell. A B cell is a lymphocyte of B lineage with the phenotype CD19-positive and capable of B cell mediated immunity.	tmpzr1t_l9r_go_relaxed.owl	B lymphocyte differentiation|B-lymphocyte differentiation|B-cell differentiation|B cell development					Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.						GO:0042115		biological_process											owl:Class	
GO:1902404	biolink:NamedThing	mitotic actomyosin contractile ring contraction	Any actomyosin contractile ring contraction that is involved in mitotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl	contractile ring contraction involved in cell cycle cytokinesis involved in mitotic cell cycle|mitotic actomyosin contractile ring constriction|cytokinesis, actomyosin ring contraction involved in mitotic cell cycle	https://github.com/geneontology/go-ontology/issues/21855						jl	2013-09-12T12:27:57Z					biological_process											owl:Class	
GO:1903369	biolink:NamedThing	negative regulation of foraging behavior	Any process that stops, prevents or reduces the frequency, rate or extent of foraging behavior.	tmpzr1t_l9r_go_relaxed.owl	down regulation of foraging behavior|inhibition of foraging behavior|downregulation of foraging behavior|down-regulation of foraging behavior							mr	2014-08-22T03:03:12Z					biological_process											owl:Class	
GO:0005890	biolink:NamedThing	sodium:potassium-exchanging ATPase complex	Sodium:potassium-exchanging ATPases are tetrameric proteins, consisting of two large alpha subunits and two smaller beta subunits. The alpha subunits bear the active site and penetrate the membrane, while the beta subunits carry oligosaccharide groups and face the cell exterior.	tmpzr1t_l9r_go_relaxed.owl	sodium/potassium-exchanging ATPase complex|sodium pump													cellular_component											owl:Class	
GO:0040008	biolink:NamedThing	regulation of growth	Any process that modulates the frequency, rate or extent of the growth of all or part of an organism so that it occurs at its proper speed, either globally or in a specific part of the organism's development.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0006390	biolink:NamedThing	mitochondrial transcription	The synthesis of RNA from a mitochondrial DNA template, usually by a specific mitochondrial RNA polymerase.	tmpzr1t_l9r_go_relaxed.owl	transcription from mitochondrial promoter	https://github.com/geneontology/go-ontology/issues/14854												biological_process											owl:Class	
GO:0036484	biolink:NamedThing	trunk neural crest cell migration	The characteristic movement of trunk neural crest cells from the neural tube to other locations in the vertebrate embryo.	tmpzr1t_l9r_go_relaxed.owl	trunk NCC migration							bf	2014-08-26T15:27:44Z					biological_process											owl:Class	
GO:0035290	biolink:NamedThing	trunk segmentation	Partitioning of the blastoderm embryo into trunk segmental units. In Drosophila, the trunk segments include thoracic segments and abdominal segments A1 to A8.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0004946	biolink:NamedThing	bombesin receptor activity	Combining with bombesin to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0031989	biolink:NamedThing	bombesin receptor signaling pathway	The series of molecular signals generated as a consequence of a bombesin receptor binding to one of its physiological ligands.	tmpzr1t_l9r_go_relaxed.owl	bombesin receptor signalling pathway													biological_process											owl:Class	
GO:0005980	biolink:NamedThing	glycogen catabolic process	The chemical reactions and pathways resulting in the breakdown of glycogen, a polydisperse, highly branched glucan composed of chains of D-glucose residues.	tmpzr1t_l9r_go_relaxed.owl	glycogen catabolism|glycogenolysis|glycogen degradation|glycogen breakdown				MetaCyc:GLYCOCAT-PWY									biological_process											owl:Class	
GO:1902669	biolink:NamedThing	positive regulation of axon guidance	Any process that activates or increases the frequency, rate or extent of axon guidance.	tmpzr1t_l9r_go_relaxed.owl	upregulation of axon chemotaxis|activation of axon growth cone guidance|up-regulation of axon guidance|positive regulation of axon growth cone guidance|activation of axon guidance|activation of axon pathfinding|up-regulation of axon chemotaxis|up regulation of axon guidance|positive regulation of axon chemotaxis|up regulation of axon chemotaxis|up-regulation of axon pathfinding|upregulation of axon guidance|upregulation of axon growth cone guidance|positive regulation of axon pathfinding|up-regulation of axon growth cone guidance|up regulation of axon growth cone guidance|activation of axon chemotaxis|upregulation of axon pathfinding|up regulation of axon pathfinding							hjd	2014-01-31T18:50:29Z					biological_process											owl:Class	
GO:0120101	biolink:NamedThing	bacterial-type flagellum stator complex	A hetero-hexameric complex of 2 membrane proteins, A and B, with stoichiometry A4B2. The A and B proteins form a channel through which flow the ions that power the bacterial-type flagellum. They form the stator, or nonrotating portion, of the flagellum motor with the B protein apparently attached to the peptidoglycan cell wall. Examples include the H+ driven MotA-MotB stator complex of Escherichia coli and Salmonella enterica, and the Na+ driven PomA-PomB stator complex of Vibrio and Shewanella species.	tmpzr1t_l9r_go_relaxed.owl	bacterial-type flagellum torque generator complex|bacterial-type flagellum motor force generator complex							krc	2017-10-03T16:06:16Z					cellular_component											owl:Class	
GO:0120100	biolink:NamedThing	bacterial-type flagellum motor	A transmembrane complex embedded in the cytoplasmic membrane which is the motor force, or torque, generator of the bacterial-type flagellum. The motor consists of a membrane-anchored rotor complex surrounded by one or more stator complexes in the cytoplasmic membrane. The stator consists of a hetero-hexameric complex of 2 membrane proteins, A and B, with stoichiometry A4B2. Examples are the H+ driven MotA-MotB stator complex of Escherichia coli and Salmonella enterica, and the Na+ driven PomA-PomB stator complex of Vibrio and Shewanella species. The rotor complex consists of a membrane-anchored ring and the motor switch complex, which controls the direction of flagellar rotation.	tmpzr1t_l9r_go_relaxed.owl								krc	2017-10-03T15:44:35Z					cellular_component											owl:Class	
GO:0072378	biolink:NamedThing	blood coagulation, fibrin clot formation	A protein activation cascade that contributes to blood coagulation and consists of the cascade of enzymatic reactions initiated by physical damage to the wall of a blood vessel, leading to the formation of a formation of a fibrin clot at the site of the injury. The process also includes numerous positive and negative regulatory events.	tmpzr1t_l9r_go_relaxed.owl						See also the biological process term 'blood coagulation, intrinsic pathway ; GO:0007597'.		mah	2010-11-22T03:09:32Z					biological_process											owl:Class	
GO:1902041	biolink:NamedThing	regulation of extrinsic apoptotic signaling pathway via death domain receptors	Any process that modulates the frequency, rate or extent of extrinsic apoptotic signaling pathway via death domain receptors.	tmpzr1t_l9r_go_relaxed.owl	regulation of death receptor-mediated apoptosis							lb	2013-04-03T07:16:59Z					biological_process											owl:Class	
GO:0006142	biolink:NamedThing	regulation of pyrimidine nucleobase metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving pyrimidine nucleobases.	tmpzr1t_l9r_go_relaxed.owl	regulation of pyrimidine base metabolic process|regulation of pyrimidine base metabolism													biological_process											owl:Class	
GO:0098909	biolink:NamedThing	regulation of cardiac muscle cell action potential involved in regulation of contraction	Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a cardiac muscle cell contributing to the regulation of its contraction.	tmpzr1t_l9r_go_relaxed.owl								tb	2011-11-10T07:45:11Z					biological_process											owl:Class	
GO:0038021	biolink:NamedThing	leptin receptor activity	Combining with the fat-cell specific hormone leptin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-06-27T01:36:45Z					molecular_function											owl:Class	
GO:0033210	biolink:NamedThing	leptin-mediated signaling pathway	A series of molecular signals initiated by the binding of leptin to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. Leptin is a hormone manufactured primarily in the adipocytes of white adipose tissue, and the level of circulating leptin is directly proportional to the total amount of fat in the body.	tmpzr1t_l9r_go_relaxed.owl	leptin-mediated signalling pathway|adipocytokine signaling pathway													biological_process											owl:Class	
GO:0033630	biolink:NamedThing	positive regulation of cell adhesion mediated by integrin	Any process that activates or increases the frequency, rate, or extent of cell adhesion mediated by integrin.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of cell adhesion mediated by integrin complex													biological_process											owl:Class	
GO:0070947	biolink:NamedThing	neutrophil-mediated killing of fungus	The directed killing of a fungal cell by a neutrophil.	tmpzr1t_l9r_go_relaxed.owl	neutrophil mediated killing of fungus							mah	2009-10-01T02:07:44Z					biological_process											owl:Class	
GO:0036363	biolink:NamedThing	transforming growth factor beta activation	The release of transforming growth factor beta (TGF-beta) from its latent state. TGF-beta is secreted as part of a large latent complex (LLC) that is targeted to the extracellular matrix. Release of TGFbeta from its latent state is required for TGFbeta to bind to its receptors, and can occur by a variety of mechanisms.	tmpzr1t_l9r_go_relaxed.owl	L-TGF-beta activation|TGF-beta activation|TGFbeta activation|latent TGF-beta activation|TGF-B activation|TGFB activation							bf	2012-09-24T10:06:56Z					biological_process											owl:Class	
GO:0051132	biolink:NamedThing	NK T cell activation	The change in morphology and behavior of a mature or immature natural killer T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.	tmpzr1t_l9r_go_relaxed.owl	NT cell activation|natural T cell activation|NKT cell activation|natural killer T cell activation|NK T lymphocyte activation|NK T-lymphocyte activation|NK T-cell activation					Note that NK T cells are a distinct lineage of T cells expressing natural killer cell markers and having T cell receptors characterized by the usage of a restricted repetoire of variable region gene segments.								biological_process											owl:Class	
GO:1903455	biolink:NamedThing	negative regulation of androst-4-ene-3,17-dione biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of androst-4-ene-3,17-dione biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of androst-4-ene-3,17-dione formation|down regulation of androst-4-ene-3,17-dione synthesis|downregulation of androst-4-ene-3,17-dione biosynthesis|inhibition of androst-4-ene-3,17-dione biosynthetic process|downregulation of androst-4-ene-3,17-dione synthesis|inhibition of androst-4-ene-3,17-dione formation|negative regulation of androst-4-ene-3,17-dione anabolism|inhibition of androst-4-ene-3,17-dione anabolism|down-regulation of androst-4-ene-3,17-dione synthesis|negative regulation of androst-4-ene-3,17-dione biosynthesis|down-regulation of androst-4-ene-3,17-dione biosynthetic process|inhibition of androst-4-ene-3,17-dione biosynthesis|downregulation of androstenedione biosynthetic process|negative regulation of androst-4-ene-3,17-dione synthesis|downregulation of androst-4-ene-3,17-dione formation|down-regulation of androstenedione biosynthetic process|down regulation of androst-4-ene-3,17-dione biosynthetic process|inhibition of androst-4-ene-3,17-dione synthesis|inhibition of androstenedione|downregulation of androst-4-ene-3,17-dione biosynthetic process|down-regulation of androst-4-ene-3,17-dione biosynthesis|down regulation of androst-4-ene-3,17-dione anabolism|down regulation of androstenedione biosynthetic process|down regulation of androst-4-ene-3,17-dione biosynthesis|down-regulation of androst-4-ene-3,17-dione anabolism|down-regulation of androst-4-ene-3,17-dione formation|negative regulation of androstenedione biosynthetic process|downregulation of androst-4-ene-3,17-dione anabolism|down regulation of androst-4-ene-3,17-dione formation							mr	2014-09-22T14:36:59Z					biological_process											owl:Class	
GO:1903449	biolink:NamedThing	androst-4-ene-3,17-dione biosynthetic process	The chemical reactions and pathways resulting in the formation of androst-4-ene-3,17-dione.	tmpzr1t_l9r_go_relaxed.owl	androstenedione biosynthetic process|androst-4-ene-3,17-dione anabolism|androst-4-ene-3,17-dione synthesis|androst-4-ene-3,17-dione biosynthesis|androst-4-ene-3,17-dione formation							mr	2014-09-19T20:18:19Z					biological_process											owl:Class	
GO:0061575	biolink:NamedThing	cyclin-dependent protein serine/threonine kinase activator activity	Binds to and increases the activity of a cyclin-dependent protein serine/threonine kinase.	tmpzr1t_l9r_go_relaxed.owl	cyclin-dependent protein kinase 5 activator activity							dph	2013-10-08T13:50:35Z			GO:0016534|GO:0016535		molecular_function											owl:Class	
GO:0072145	biolink:NamedThing	proximal convoluted tubule segment 1 cell development	The process whose specific outcome is the progression of an S1 cell in the kidney over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl	S1 cell development							mah	2010-02-24T01:54:56Z					biological_process											owl:Class	
GO:0072062	biolink:NamedThing	proximal convoluted tubule segment 1 cell differentiation	The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the S1 cells of the kidney as it progresses from its formation to the mature state.	tmpzr1t_l9r_go_relaxed.owl	S1 cell differentiation							mah	2010-01-25T04:11:17Z					biological_process											owl:Class	
GO:0043308	biolink:NamedThing	eosinophil degranulation	The regulated exocytosis of secretory granules containing preformed mediators such as major basic protein, eosinophil peroxidase, and eosinophil cationic protein by an eosinophil.	tmpzr1t_l9r_go_relaxed.owl	eosinophil granule exocytosis													biological_process											owl:Class	
GO:0002447	biolink:NamedThing	eosinophil mediated immunity	Any process involved in the carrying out of an immune response by an eosinophil.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0002303	biolink:NamedThing	gamma-delta T cell differentiation involved in immune response	The process in which an antigenically naive gamma-delta T cell acquires the specialized features of an effector, regulatory, or memory T cell and contributes to an immune response. Effector T cells include cells which provide T cell help or exhibit cytotoxicity towards other cells.	tmpzr1t_l9r_go_relaxed.owl	gamma-delta T lymphocyte differentiation during immune response|gamma-delta T-lymphocyte differentiation during immune response|gamma-delta T cell development involved in immune response|gamma-delta T cell differentiation during immune response|gamma-delta T-cell differentiation during immune response					Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.								biological_process											owl:Class	
GO:0017080	biolink:NamedThing	sodium channel regulator activity	Binds to and modulates the activity of a sodium channel.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0052928	biolink:NamedThing	CTP:3'-cytidine-tRNA cytidylyltransferase activity	Catalysis of the reaction: a tRNA with a 3' cytidine + CTP = a tRNA with a 3' CC end + diphosphate.	tmpzr1t_l9r_go_relaxed.owl					EC:2.7.7.72|KEGG_REACTION:R09384									molecular_function											owl:Class	
GO:0042896	biolink:NamedThing	chloramphenicol transmembrane transporter activity	Enables the transfer of chloramphenicol, a broad-spectrum antibiotic that inhibits bacterial protein synthesis, from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	chloramphenicol transporter activity													molecular_function											owl:Class	
GO:0042892	biolink:NamedThing	chloramphenicol transmembrane transport	The directed movement of chloramphenicol, a broad-spectrum antibiotic that inhibits bacterial protein synthesis, across a lipid bilayer, from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	chloramphenicol transport													biological_process											owl:Class	
GO:1900450	biolink:NamedThing	negative regulation of glutamate receptor signaling pathway	Any process that stops, prevents or reduces the frequency, rate or extent of glutamate receptor signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	downregulation of glutamate signalling pathway|down regulation of glutamate signalling pathway|down-regulation of glutamate receptor signaling pathway|down regulation of glutamate receptor signaling pathway|downregulation of glutamate receptor signaling pathway|down regulation of glutamate signaling pathway|downregulation of glutamate signaling pathway|inhibition of glutamate signaling pathway|inhibition of glutamate receptor signaling pathway|down-regulation of glutamate signalling pathway|negative regulation of glutamate signaling pathway|down-regulation of glutamate signaling pathway|negative regulation of glutamate signalling pathway|inhibition of glutamate signalling pathway							rl	2012-04-27T03:45:53Z					biological_process											owl:Class	
GO:0007215	biolink:NamedThing	glutamate receptor signaling pathway	A series of molecular signals initiated by the binding of glutamate to a glutamate receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.	tmpzr1t_l9r_go_relaxed.owl	glutamate signalling pathway|glutamate signaling pathway													biological_process											owl:Class	
GO:1902462	biolink:NamedThing	positive regulation of mesenchymal stem cell proliferation	Any process that activates or increases the frequency, rate or extent of mesenchymal stem cell proliferation.	tmpzr1t_l9r_go_relaxed.owl	activation of mesenchymal stem cell proliferation|up-regulation of MSC proliferation|positive regulation of MSC proliferation|activation of MSC proliferation|upregulation of MSC proliferation|up regulation of MSC proliferation|upregulation of mesenchymal stem cell proliferation|up-regulation of mesenchymal stem cell proliferation|up regulation of mesenchymal stem cell proliferation							pm	2013-10-22T10:01:17Z					biological_process											owl:Class	
GO:0035023	biolink:NamedThing	regulation of Rho protein signal transduction	Any process that modulates the frequency, rate or extent of Rho protein signal transduction.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0036473	biolink:NamedThing	cell death in response to oxidative stress	Any biological process that results in permanent cessation of all vital functions of a cell upon exposure to an oxidative stress stimulus.	tmpzr1t_l9r_go_relaxed.owl						This term should not be used for direct annotation. The only exception should be when experimental data (e.g., staining with trypan blue or propidium iodide) show that cell death has occurred in response to an oxidative stress stimulus, but fail to provide details on death modality (accidental versus programmed). When information is provided on the cell death mechanism, annotations should be made to the appropriate descendant of 'cell death' (such as, but not limited to, GO:0097300 'programmed necrotic cell death', GO:0006915 'apoptotic process' or GO:0097468 'programmed cell death in response to reactive oxygen species'). Also, if experimental data suggest that a gene product influences cell death indirectly, rather than being involved in the death process directly, consider annotating to a 'regulation' term.		bf	2014-07-21T11:37:03Z					biological_process											owl:Class	
GO:0051248	biolink:NamedThing	negative regulation of protein metabolic process	Any process that stops, prevents, or reduces the frequency, rate or extent of chemical reactions and pathways involving a protein.	tmpzr1t_l9r_go_relaxed.owl	downregulation of protein metabolic process|negative regulation of protein metabolism|down regulation of protein metabolic process|down-regulation of protein metabolic process|inhibition of protein metabolic process													biological_process											owl:Class	
GO:0060140	biolink:NamedThing	modulation by virus of syncytium formation via plasma membrane fusion	The formation in a cell that has been targeted by a virus of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0006948	biolink:NamedThing	induction by virus of host cell-cell fusion	The process of syncytia-forming cell-cell fusion, caused by a virus.	tmpzr1t_l9r_go_relaxed.owl	viral-induced host cell-cell fusion|induction by virus of cell-cell fusion in host|viral-induced membrane fusion|viral-induced cell-cell fusion					Where syncytium formation results in the spread of virus in the host, also consider annotating to the term 'spread of virus in multicellular host ; GO:0046739'.								biological_process											owl:Class	
GO:0072495	biolink:NamedThing	host cell Cajal body	A class of nuclear body in the eukaryotic host cell, first seen after silver staining by Ramon y Cajal in 1903, enriched in small nuclear ribonucleoproteins, and certain general RNA polymerase II transcription factors; ultrastructurally, they appear as a tangle of coiled, electron-dense threads roughly 0.5 micrometers in diameter; involved in aspects of snRNP biogenesis; the protein coilin serves as a marker for Cajal bodies. Some argue that Cajal bodies are the sites for preassembly of transcriptosomes, unitary particles involved in transcription and processing of RNA. The host is the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	host cell coiled body|coiled body of host							mah	2010-12-15T11:51:12Z					cellular_component											owl:Class	
GO:0044095	biolink:NamedThing	host cell nucleoplasm	That part of a host cell's nuclear content other than the chromosomes or the nucleolus. The host is the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl								jl	2009-04-22T02:02:51Z					cellular_component											owl:Class	
GO:0007620	biolink:NamedThing	copulation	The act of sexual union between male and female, involving the transfer of sperm.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0009757	biolink:NamedThing	hexose mediated signaling	A series of molecular signals mediated by the detection of hexose.	tmpzr1t_l9r_go_relaxed.owl	hexose mediated signalling													biological_process											owl:Class	
GO:0071331	biolink:NamedThing	cellular response to hexose stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hexose stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-12-10T05:37:00Z					biological_process											owl:Class	
GO:0016907	biolink:NamedThing	G protein-coupled acetylcholine receptor activity	Combining with acetylcholine and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.	tmpzr1t_l9r_go_relaxed.owl	G-protein coupled acetylcholine receptor activity|muscarinic acetylcholine receptor activity|acetylcholine receptor activity, G-protein coupled|metabotropic acetylcholine receptor activity|G protein coupled acetylcholine receptor activity											GO:0004981		molecular_function											owl:Class	
GO:0007213	biolink:NamedThing	G protein-coupled acetylcholine receptor signaling pathway	Any series of molecular signals initiated by an acetylcholine receptor on the surface of the target cell binding to one of its physiological ligands, and proceeding with the activated receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction and ends with regulation of a downstream cellular process, e.g. transcription.	tmpzr1t_l9r_go_relaxed.owl	acetylcholine receptor signalling, muscarinic pathway|G-protein coupled acetylcholine receptor signaling pathway|muscarinic acetylcholine receptor signaling pathway													biological_process											owl:Class	
GO:0010090	biolink:NamedThing	trichome morphogenesis	The process in which the structures of a hair cell (trichome) cell are generated and organized. This process occurs while the initially relatively unspecialized epidermal cell is acquiring the specialized features of a hair cell. An example of this process is found in Arabidopsis thaliana.	tmpzr1t_l9r_go_relaxed.owl	trichome cell morphogenesis during differentiation											GO:0048272		biological_process											owl:Class	
GO:1901683	biolink:NamedThing	arsenate ion transmembrane transporter activity	Enables the transfer of an arsenate ion from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl								tb	2012-12-04T23:26:27Z					molecular_function											owl:Class	
GO:1901684	biolink:NamedThing	arsenate ion transmembrane transport	The process in which arsenate is transported across a membrane.	tmpzr1t_l9r_go_relaxed.owl						Note that this term is not intended for use in annotating lateral movement within membranes.		tb	2012-12-04T23:26:36Z					biological_process											owl:Class	
GO:0002634	biolink:NamedThing	regulation of germinal center formation	Any process that modulates the frequency, rate, or extent of germinal center formation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0002467	biolink:NamedThing	germinal center formation	The process in which germinal centers form. A germinal center is a specialized microenvironment formed when activated B cells enter lymphoid follicles. Germinal centers are the foci for B cell proliferation and somatic hypermutation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0001942	biolink:NamedThing	hair follicle development	The process whose specific outcome is the progression of the hair follicle over time, from its formation to the mature structure. A hair follicle is a tube-like opening in the epidermis where the hair shaft develops and into which the sebaceous glands open.	tmpzr1t_l9r_go_relaxed.owl												GO:0001943		biological_process											owl:Class	
GO:0060029	biolink:NamedThing	convergent extension involved in organogenesis	The morphogenetic process in which an epithelium narrows along one axis and lengthens in a perpendicular axis contribution to the shaping of an organ.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0000275	biolink:NamedThing	mitochondrial proton-transporting ATP synthase complex, catalytic sector F(1)	The catalytic sector of the mitochondrial hydrogen-transporting ATP synthase; it comprises the catalytic core and central stalk, and is peripherally associated with the mitochondrial inner membrane when the entire ATP synthase is assembled.	tmpzr1t_l9r_go_relaxed.owl	proton-transporting ATP synthase complex, catalytic core F(1)|hydrogen-transporting ATP synthase, F1 sector					See also the cellular component term 'mitochondrial inner membrane ; GO:0005743'.								cellular_component											owl:Class	
GO:2001185	biolink:NamedThing	regulation of CD8-positive, alpha-beta T cell activation	Any process that modulates the frequency, rate or extent of CD8-positive, alpha-beta T cell activation.	tmpzr1t_l9r_go_relaxed.owl								yaf	2011-11-03T01:16:51Z					biological_process											owl:Class	
GO:0036037	biolink:NamedThing	CD8-positive, alpha-beta T cell activation	The change in morphology and behavior of a CD8-positive, alpha-beta T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-11-03T10:34:12Z					biological_process											owl:Class	
GO:2000640	biolink:NamedThing	positive regulation of SREBP signaling pathway	Any process that activates or increases the frequency, rate or extent of the SREBP signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of SREBP-mediated signalling pathway|positive regulation of SREBP-mediated signaling pathway							vk	2011-04-20T02:46:05Z					biological_process											owl:Class	
GO:0032933	biolink:NamedThing	SREBP signaling pathway	A series of molecular signals from the endoplasmic reticulum to the nucleus generated as a consequence of decreased levels of one or more sterols (and in some yeast, changes in oxygen levels) and which proceeds through activation of a sterol response element binding transcription factor (SREBP) to result in up-regulation of target gene transcription.	tmpzr1t_l9r_go_relaxed.owl	endoplasmic reticulum-nuclear sterol response pathway|sterol depletion response, SREBP target gene transcriptional activation|stimulation of sterol regulatory element binding protein target gene transcription|SREBP-mediated signaling pathway|sterol regulatory element binding protein target gene transcriptional activation|endoplasmic reticulum to nucleus sterol response pathway|up regulation of sterol regulatory element binding protein target gene transcription|SREBP signalling|sterol response element binding protein signaling pathway|positive regulation of sterol regulatory element binding protein target gene transcription involved in sterol depletion response|SREBP target gene transcriptional activation|upregulation of sterol regulatory element binding protein target gene transcription|SREBP-mediated signalling pathway|positive regulation of transcription via sterol regulatory element binding involved in ER-nuclear sterol response pathway|activation of sterol regulatory element binding protein target gene transcription|ER-nuclear sterol response pathway|up-regulation of sterol regulatory element binding protein target gene transcription|positive regulation of transcription via sterol regulatory element binding|ER to nucleus sterol response pathway|positive regulation of sterol regulatory element binding protein target gene transcription											GO:0006994|GO:0035104|GO:0030967		biological_process											owl:Class	
GO:1903891	biolink:NamedThing	regulation of ATF6-mediated unfolded protein response	Any process that modulates the frequency, rate or extent of the ATF6-mediated unfolded protein response.	tmpzr1t_l9r_go_relaxed.owl	regulation of UPR signaling by ATF6 stress sensor|regulation of activating transcription factor 6 signaling in unfolded protein response|regulation of ATF6 signal transduction pathway|regulation of ATF6 signaling in response to endoplasmic reticulum stress|regulation of ATF6-alpha UPR branch|regulation of ATF6 branch of UPR|regulation of endoplasmic reticulum unfolded protein response; ATF6 signaling|regulation of ATF6-beta UPR branch							bf	2015-02-09T10:17:15Z					biological_process											owl:Class	
GO:1905410	biolink:NamedThing	regulation of mitotic cohesin unloading	Any process that modulates the frequency, rate or extent of mitotic cohesin unloading.	tmpzr1t_l9r_go_relaxed.owl								vw	2016-08-25T15:45:22Z					biological_process											owl:Class	
GO:0061781	biolink:NamedThing	mitotic cohesin unloading	Negative regulation of sister chromatid cohesion by the topological unlinking of a cohesin ring to DNA as part of the mitotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl								dph	2016-08-24T09:43:07Z					biological_process											owl:Class	
GO:1902608	biolink:NamedThing	positive regulation of large conductance calcium-activated potassium channel activity	Any process that activates or increases the frequency, rate or extent of large conductance calcium-activated potassium channel activity.	tmpzr1t_l9r_go_relaxed.owl	activation of large conductance KCa channels|up regulation of BK calcium-activated potassium channel activity|upregulation of BK channel activity|upregulation of large conductance calcium-activated potassium channel activity|upregulation of large conductance KCa channels|positive regulation of BK calcium-activated potassium channel activity|positive regulation of large conductance KCa channels|up regulation of large conductance KCa channels|activation of large conductance calcium-activated potassium channel activity|upregulation of BK KCa channels|positive regulation of BK KCa channels|up-regulation of large conductance KCa channels|activation of BK calcium-activated potassium channel activity|up regulation of large conductance calcium-activated potassium channel activity|up-regulation of BK KCa channels|positive regulation of BK channel activity|up-regulation of large conductance calcium-activated potassium channel activity|up-regulation of BK calcium-activated potassium channel activity|up regulation of BK KCa channels|up regulation of BK channel activity|activation of BK channel activity|up-regulation of BK channel activity|upregulation of BK calcium-activated potassium channel activity|activation of BK KCa channels							sl	2014-01-02T18:51:21Z					biological_process											owl:Class	
GO:1905393	biolink:NamedThing	plant organ formation	The process that gives rise to the plant organ. This process pertains to the initial formation of a structure from unspecified parts.	tmpzr1t_l9r_go_relaxed.owl								tb	2016-08-24T00:21:27Z					biological_process											owl:Class	
GO:0014804	biolink:NamedThing	terminal cisterna lumen	The region between the inner and outer lipid bilayers of the terminal cisterna envelope. This space is enriched in calsequestrin.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0030794	biolink:NamedThing	(S)-coclaurine-N-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + (S)-coclaurine = S-adenosyl-L-homocysteine + (S)-N-methylcoclaurine.	tmpzr1t_l9r_go_relaxed.owl	S-adenosyl-L-methionine:(S)-coclaurine-N-methyltransferase activity				MetaCyc:2.1.1.140-RXN|EC:2.1.1.140|RHEA:17409									molecular_function											owl:Class	
GO:0007055	biolink:NamedThing	spindle assembly involved in male meiosis II	The formation of the spindle during meiosis II of a meiotic cell cycle in males. An example of this is found in Drosophila melanogaster.	tmpzr1t_l9r_go_relaxed.owl	male meiosis II spindle assembly													biological_process											owl:Class	
GO:0046824	biolink:NamedThing	positive regulation of nucleocytoplasmic transport	Any process that activates or increases the frequency, rate or extent of the directed movement of substances between the nucleus and the cytoplasm.	tmpzr1t_l9r_go_relaxed.owl	activation of nucleocytoplasmic transport|stimulation of nucleocytoplasmic transport|upregulation of nucleocytoplasmic transport|up regulation of nucleocytoplasmic transport|up-regulation of nucleocytoplasmic transport													biological_process											owl:Class	
GO:0034878	biolink:NamedThing	2-hydroxyisonicotinate dehydrogenase activity	Catalysis of the reaction: 2-hydroxyisonicotinate + acceptor + H2O = citrazinate + reduced acceptor.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r1338									molecular_function											owl:Class	
GO:0003249	biolink:NamedThing	cell proliferation involved in heart valve morphogenesis	The multiplication or reproduction of cells that contributes to the shaping of a heart valve.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-10-13T01:59:19Z					biological_process											owl:Class	
GO:2000793	biolink:NamedThing	cell proliferation involved in heart valve development	Any cell proliferation that is involved in heart valve development.	tmpzr1t_l9r_go_relaxed.owl	cell proliferation of heart valve development|cell proliferation of cardiac valve development							bf	2011-06-24T03:12:15Z					biological_process											owl:Class	
GO:0070458	biolink:NamedThing	cellular detoxification of nitrogen compound	Any cellular process that reduces or removes the toxicity of nitrogenous compounds which are dangerous or toxic. This includes the aerobic conversion of toxic compounds to harmless substances.	tmpzr1t_l9r_go_relaxed.owl	cellular detoxification of nitrogenous compound													biological_process											owl:Class	
GO:0014005	biolink:NamedThing	microglia development	The process aimed at the progression of a microglial cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.	tmpzr1t_l9r_go_relaxed.owl	microglial cell development													biological_process											owl:Class	
GO:0106222	biolink:NamedThing	long noncoding RNA binding	Binding to a long noncoding  RNA (lncRNA).	tmpzr1t_l9r_go_relaxed.owl	lncRNA binding							hjd	2019-08-27T14:52:58Z					molecular_function											owl:Class	
GO:1990929	biolink:NamedThing	sulfoquinovosidase activity	Catalyzes the hydrolysis of terminal non-reducing alpha-sulfoquinovoside residues in alpha-sulfoquinovosyl diacylglycerides and alpha-sulfoquinovosyl glycerol, generating alpha-sulfoquinovose.	tmpzr1t_l9r_go_relaxed.owl								tb	2016-02-19T01:18:37Z					molecular_function											owl:Class	
GO:2000061	biolink:NamedThing	regulation of ureter smooth muscle cell differentiation	Any process that modulates the frequency, rate or extent of ureter smooth muscle cell differentiation.	tmpzr1t_l9r_go_relaxed.owl								jl	2010-08-20T01:44:16Z					biological_process											owl:Class	
GO:0008631	biolink:NamedThing	intrinsic apoptotic signaling pathway in response to oxidative stress	A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced in response to oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, and ends when the execution phase of apoptosis is triggered.	tmpzr1t_l9r_go_relaxed.owl	oxidative stress-induced intrinsic apoptotic signaling pathway|induction of apoptosis by oxidative stress													biological_process											owl:Class	
GO:0016345	biolink:NamedThing	female meiotic chromosome movement towards spindle pole	The directed movement of chromosomes in the center of the spindle towards the spindle poles, mediated by the shortening of microtubules attached to the chromosomes, during female meiosis.	tmpzr1t_l9r_go_relaxed.owl	female meiotic chromosome movement to spindle pole|female meiotic chromosome movement|chromosome movement towards spindle pole during female meiosis													biological_process											owl:Class	
GO:0032087	biolink:NamedThing	regulation of type IV site-specific deoxyribonuclease activity	Any process that modulates the frequency, rate or extent of a type IV restriction endodeoxyribonuclease activity.	tmpzr1t_l9r_go_relaxed.owl	regulation of type IV restriction endodeoxyribonuclease activity|type IV restriction endodeoxyribonuclease regulator|type IV restriction enzyme regulator													biological_process											owl:Class	
GO:0036002	biolink:NamedThing	pre-mRNA binding	Binding to a pre-messenger RNA (pre-mRNA), an intermediate molecule between DNA and protein that may contain introns and, at least in part, encodes one or more proteins. Introns are removed from pre-mRNA to form a mRNA molecule.	tmpzr1t_l9r_go_relaxed.owl	protein-coding primary transcript binding							bf	2011-09-16T10:23:37Z					molecular_function											owl:Class	
GO:0106349	biolink:NamedThing	snRNA methylation	The posttranscriptional addition of methyl groups to specific residues in an snRNA molecule.	tmpzr1t_l9r_go_relaxed.owl								hjd	2020-12-18T15:55:19Z					biological_process											owl:Class	
GO:0051039	biolink:NamedThing	positive regulation of transcription involved in meiotic cell cycle	Any process that activates or increases the frequency, rate or extent of transcription as part of a meiotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of meiotic transcription|up-regulation of transcription during meiosis|stimulation of transcription during meiosis|up regulation of transcription during meiosis|positive regulation of transcription, meiotic|activation of transcription during meiosis|upregulation of transcription during meiosis													biological_process											owl:Class	
GO:1901109	biolink:NamedThing	granaticin biosynthetic process	The chemical reactions and pathways resulting in the formation of granaticin.	tmpzr1t_l9r_go_relaxed.owl	granaticin synthesis|granaticin formation|granaticin anabolism|granaticin biosynthesis							yaf	2012-07-11T02:51:40Z					biological_process											owl:Class	
GO:1901107	biolink:NamedThing	granaticin metabolic process	The chemical reactions and pathways involving granaticin.	tmpzr1t_l9r_go_relaxed.owl	granaticin metabolism							yaf	2012-07-11T02:51:08Z					biological_process											owl:Class	
GO:0097237	biolink:NamedThing	cellular response to toxic substance	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a toxic stimulus.	tmpzr1t_l9r_go_relaxed.owl								pr	2012-02-02T12:23:31Z					biological_process											owl:Class	
GO:0018122	biolink:NamedThing	peptidyl-asparagine ADP-ribosylation	The transfer, from NAD, of ADP-ribose to peptidyl-asparagine to form peptidyl-N4-(ADP-ribosyl)-L-asparagine.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0231									biological_process											owl:Class	
GO:0102563	biolink:NamedThing	aurachin C monooxygenase activity	Catalysis of the reaction: aurachin C + O2 + H+ + NAD(P)H <=> aurachin C epoxide + H2O + NAD(P).	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-15029									molecular_function											owl:Class	
GO:0006589	biolink:NamedThing	octopamine biosynthetic process	The chemical reactions and pathways resulting in the formation of octopamine, 1-(p-hydroxyphenyl)-2-aminoethanol. The D enantiomer is about one-tenth as active as norepinephrine and is found in the salivary glands of Octopus and Eledone species.	tmpzr1t_l9r_go_relaxed.owl	octopamine synthesis|octopamine anabolism|octopamine formation|octopamine biosynthesis													biological_process											owl:Class	
GO:0046333	biolink:NamedThing	octopamine metabolic process	The chemical reactions and pathways involving octopamine, 1-(p-hydroxyphenyl)-2-aminoethanol. The D enantiomer is about one-tenth as active as norepinephrine and is found in the salivary glands of Octopus and Eledone species.	tmpzr1t_l9r_go_relaxed.owl	octopamine metabolism													biological_process											owl:Class	
GO:0032505	biolink:NamedThing	reproduction of a single-celled organism	The biological process in which new individuals are produced by one or two single-celled organisms. The new individuals inherit some proportion of their genetic material from the parent or parents.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0000003	biolink:NamedThing	reproduction	The production of new individuals that contain some portion of genetic material inherited from one or more parent organisms.	tmpzr1t_l9r_go_relaxed.owl	reproductive physiological process				Wikipedia:Reproduction							GO:0019952|GO:0050876		biological_process											owl:Class	
GO:0051163	biolink:NamedThing	D-arabitol metabolic process	The chemical reactions and pathways involving D-arabitol, the pentitol derived from arabinose or lyxose by reduction of the aldehyde group. The D enantiomer is present in lichens and mushrooms.	tmpzr1t_l9r_go_relaxed.owl	D-arabitol metabolism													biological_process											owl:Class	
GO:0009067	biolink:NamedThing	aspartate family amino acid biosynthetic process	The chemical reactions and pathways resulting in the formation of amino acids of the aspartate family, comprising asparagine, aspartate, lysine, methionine and threonine.	tmpzr1t_l9r_go_relaxed.owl	aspartate family amino acid biosynthesis|aspartate family amino acid anabolism|aspartate family amino acid formation|aspartate family amino acid synthesis													biological_process											owl:Class	
GO:0050682	biolink:NamedThing	AF-2 domain binding	Binding to an AF-2 protein domain, a highly conserved ligand-dependent transactivation domain which is essential for receptor-mediated transcriptional activation.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0047888	biolink:NamedThing	fatty acid peroxidase activity	Catalysis of the reaction: 2 H(2)O(2) + H(+) + palmitate = CO(2) + 3 H(2)O + pentadecanal.	tmpzr1t_l9r_go_relaxed.owl	long chain fatty acid peroxidase activity|fatty-acid peroxidase activity|hexadecanoate:hydrogen-peroxide oxidoreductase activity				MetaCyc:FATTY-ACID-PEROXIDASE-RXN|KEGG_REACTION:R01703|RHEA:23960|EC:1.11.1.3									molecular_function											owl:Class	
GO:0005134	biolink:NamedThing	interleukin-2 receptor binding	Binding to an interleukin-2 receptor.	tmpzr1t_l9r_go_relaxed.owl	IL-2|interleukin-2 receptor ligand													molecular_function											owl:Class	
GO:0035243	biolink:NamedThing	protein-arginine omega-N symmetric methyltransferase activity	Catalysis of the addition of a second methyl group to methylated peptidyl-arginine. Methylation is on the terminal nitrogen (omega nitrogen) residue that is not already methylated, resulting in symmetrical peptidyl-N(omega),N'(omega)-dimethyled arginine residues.	tmpzr1t_l9r_go_relaxed.owl	type II PRMT activity|S-adenosyl-L-methionine:[protein]-L-arginine N-methyltransferase ([protein]-Nomega,Nomega'-dimethyl-L-arginine-forming)|type II protein arginine methyltransferase activity				RESID:AA0069|Reactome:R-HSA-6804383|EC:2.1.1.320|RESID:AA0067|RHEA:48108	Note that type II protein arginine N-methyltransferase enzymes possess 'protein-arginine omega-N monomethyltransferase activity ; GO:0035241' and 'protein-arginine omega-N symmetric methyltransferase activity ; GO:0035243'.								molecular_function											owl:Class	
GO:0016274	biolink:NamedThing	protein-arginine N-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + (protein)-arginine = S-adenosyl-L-homocysteine + (protein)-N-methyl-arginine.	tmpzr1t_l9r_go_relaxed.owl	PRMT activity				Reactome:R-HSA-5205798|Reactome:R-HSA-8934735|Reactome:R-HSA-5218952|Reactome:R-HSA-5205822|Reactome:R-HSA-8879123|Reactome:R-HSA-5229203|Reactome:R-HSA-5205824|Reactome:R-HSA-5205820|Reactome:R-HSA-191790|Reactome:R-HSA-5229010|Reactome:R-HSA-5661126|Reactome:R-HSA-5205867									molecular_function											owl:Class	
GO:0047380	biolink:NamedThing	ADP-dependent medium-chain-acyl-CoA hydrolase activity	Catalysis of the reaction: H2O + a medium-chain acyl-CoA = a medium-chain carboxylate + CoA. Requires ADP.	tmpzr1t_l9r_go_relaxed.owl	ADP-dependent medium-chain acyl-thioester hydrolase activity|ADP-dependent medium-chain acyl-CoA hydrolase activity|ADP-dependent myristoyl-CoA thioesterase activity|ADP-dependent-medium-chain-acyl-CoA hydrolase activity|ADP-dependent medium-chain acyl coenzyme A hydrolase activity|ADP-dependent medium-chain hydrolase activity				MetaCyc:3.1.2.19-RXN|EC:3.1.2.19									molecular_function											owl:Class	
GO:0052815	biolink:NamedThing	medium-chain acyl-CoA hydrolase activity	Catalysis of the reaction: H2O + a medium-chain acyl-CoA = a medium-chain carboxylate + CoA. A medium chain is a chain of between eight and twelve carbons in length.	tmpzr1t_l9r_go_relaxed.owl	medium-chain acyl-thioester hydrolase activity|medium-chain hydrolase activity|medium-chain-acyl-CoA hydrolase activity|medium-chain acyl coenzyme A hydrolase activity							ai	2011-10-25T05:26:29Z					molecular_function											owl:Class	
GO:0009856	biolink:NamedThing	pollination	The cascade of biological processes occurring in plants beginning when the pollen lands on the female reproductive organs of a plant and continuing up to, but not including, fertilization, as defined by sperm-egg cell fusion.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Pollination									biological_process											owl:Class	
GO:1905067	biolink:NamedThing	negative regulation of canonical Wnt signaling pathway involved in heart development	Any process that stops, prevents or reduces the frequency, rate or extent of canonical Wnt signaling pathway involved in heart development.	tmpzr1t_l9r_go_relaxed.owl	down regulation of canonical Wnt-activated signaling pathway involved in heart development|down regulation of canonical Wnt signaling pathway involved in heart development|down-regulation of canonical Wnt receptor signalling pathway involved in heart development|negative regulation of canonical Wnt-activated signaling pathway involved in heart development|down-regulation of canonical Wnt receptor signaling pathway involved in heart development|downregulation of canonical Wnt-activated signaling pathway involved in heart development|inhibition of canonical Wnt signaling pathway involved in heart development|negative regulation of canonical Wnt receptor signaling pathway involved in heart development|inhibition of canonical Wnt receptor signaling pathway involved in heart development|downregulation of canonical Wnt receptor signaling pathway involved in heart development|inhibition of canonical Wnt-activated signaling pathway involved in heart development|down regulation of canonical Wnt receptor signalling pathway involved in heart development|down-regulation of canonical Wnt-activated signaling pathway involved in heart development|down-regulation of canonical Wnt signaling pathway involved in heart development|downregulation of canonical Wnt signaling pathway involved in heart development|inhibition of canonical Wnt receptor signalling pathway involved in heart development|negative regulation of canonical Wnt receptor signalling pathway involved in heart development|downregulation of canonical Wnt receptor signalling pathway involved in heart development|down regulation of canonical Wnt receptor signaling pathway involved in heart development							bc	2016-03-21T12:47:06Z					biological_process											owl:Class	
GO:1905066	biolink:NamedThing	regulation of canonical Wnt signaling pathway involved in heart development	Any process that modulates the frequency, rate or extent of canonical Wnt signaling pathway involved in heart development.	tmpzr1t_l9r_go_relaxed.owl	regulation of canonical Wnt-activated signaling pathway involved in heart development|regulation of canonical Wnt receptor signaling pathway involved in heart development|regulation of canonical Wnt receptor signalling pathway involved in heart development							bc	2016-03-21T12:46:56Z					biological_process											owl:Class	
GO:0018234	biolink:NamedThing	peptide cross-linking via 3'-(S-L-cysteinyl)-L-tyrosine	The thioether cross-linking of a cysteine residue to a tyrosine residue to form 3'-(S-L-cysteinyl)-L-tyrosine, found in galactose oxidase.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0113									biological_process											owl:Class	
GO:0031073	biolink:NamedThing	cholesterol 26-hydroxylase activity	Catalysis of the hydroxylation of cholesterol at position 26 of the side chain, to produce 26-hydroxycholesterol.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0099547	biolink:NamedThing	regulation of translation at synapse, modulating synaptic transmission	Any process that modulates synaptic transmission by regulating translation occurring at the synapse.	tmpzr1t_l9r_go_relaxed.owl						Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.								biological_process											owl:Class	
GO:0120229	biolink:NamedThing	protein localization to motile cilium	A process in which a protein is transported to, or maintained in, a location within a motile cilium.	tmpzr1t_l9r_go_relaxed.owl	protein localization to nonmotile primary cilium	https://github.com/geneontology/go-ontology/issues/19588						krc	2020-06-05T23:43:04Z					biological_process											owl:Class	
GO:0014015	biolink:NamedThing	positive regulation of gliogenesis	Any process that activates or increases the frequency, rate or extent of gliogenesis, the formation of mature glia.	tmpzr1t_l9r_go_relaxed.owl	activation of gliogenesis|upregulation of gliogenesis|up-regulation of gliogenesis|stimulation of gliogenesis|up regulation of gliogenesis													biological_process											owl:Class	
GO:0014013	biolink:NamedThing	regulation of gliogenesis	Any process that modulates the frequency, rate or extent of gliogenesis, the formation of mature glia.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0000970	biolink:NamedThing	tRNA exon ligation utilizing GTP as source of linkage phosphate	A tRNA exon ligation process in which the splice junction phosphate is derived from exogenous GTP. This type of ligation to rejoin the 5' and 3' exons of a tRNA is observed in the yeast Saccharomyces cerevisiae where the ligation reaction also produces a 2'-phosphate at the splice junction which is subsequently removed as part of the ligation process.	tmpzr1t_l9r_go_relaxed.owl								krc	2009-04-28T10:33:25Z					biological_process											owl:Class	
GO:0000968	biolink:NamedThing	tRNA exon ligation	An RNA exon ligation process that rejoins two exons of a pre-tRNA which has had the intron removed.	tmpzr1t_l9r_go_relaxed.owl								krc	2009-04-28T10:22:40Z					biological_process											owl:Class	
GO:0034882	biolink:NamedThing	cis-aconitamide amidase activity	Catalysis of the reaction: cis-aconitamide + H2O = cis-aconitate + HN3.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r1344									molecular_function											owl:Class	
GO:1901280	biolink:NamedThing	D-ribose 5-phosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of D-ribose 5-phosphate.	tmpzr1t_l9r_go_relaxed.owl	D-ribose 5-phosphate synthesis|D-ribose 5-phosphate anabolism|D-ribose 5-phosphate biosynthesis|D-ribose 5-phosphate formation							yaf	2012-08-17T15:00:27Z					biological_process											owl:Class	
GO:1900294	biolink:NamedThing	regulation of heptasaccharide transport	Any process that modulates the frequency, rate or extent of heptasaccharide transport.	tmpzr1t_l9r_go_relaxed.owl								tt	2012-04-05T07:40:40Z					biological_process											owl:Class	
GO:0002152	biolink:NamedThing	bile acid conjugation	The process in which bile acids are covalently linked to taurine or glycine.	tmpzr1t_l9r_go_relaxed.owl						The bile acid is first activated using CoA by cholate-CoA ligase activity(GO:0047747), then conjugated to taurine or glycine by glycine N-choloyltransferase activity (GO:0047963; appears to use either glycine or taurine).		hjd	2009-10-29T01:41:51Z					biological_process											owl:Class	
GO:0008206	biolink:NamedThing	bile acid metabolic process	The chemical reactions and pathways involving bile acids, a group of steroid carboxylic acids occurring in bile, where they are present as the sodium salts of their amides with glycine or taurine.	tmpzr1t_l9r_go_relaxed.owl	bile acid metabolism													biological_process											owl:Class	
GO:0009152	biolink:NamedThing	purine ribonucleotide biosynthetic process	The chemical reactions and pathways resulting in the formation of a purine ribonucleotide, a compound consisting of ribonucleoside (a purine base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.	tmpzr1t_l9r_go_relaxed.owl	purine ribonucleotide biosynthesis|purine ribonucleotide formation|purine ribonucleotide synthesis|purine ribonucleotide anabolism													biological_process											owl:Class	
GO:1903626	biolink:NamedThing	positive regulation of DNA catabolic process	Any process that activates or increases the frequency, rate or extent of DNA catabolic process.	tmpzr1t_l9r_go_relaxed.owl	up regulation of DNA catabolic process|activation of DNA breakdown|up regulation of DNA breakdown|positive regulation of DNA breakdown|up-regulation of DNA degradation|up regulation of DNA catabolism|up-regulation of DNA catabolism|activation of DNA catabolic process|positive regulation of DNA catabolism|upregulation of DNA breakdown|positive regulation of DNA degradation|up-regulation of DNA catabolic process|upregulation of DNA catabolic process|up regulation of DNA degradation|upregulation of DNA degradation|activation of DNA catabolism|activation of DNA degradation|upregulation of DNA catabolism|up-regulation of DNA breakdown							sl	2014-11-19T22:36:51Z					biological_process											owl:Class	
GO:0002012	biolink:NamedThing	vasoconstriction of artery involved in chemoreceptor response to lowering of systemic arterial blood pressure	A process that is triggered by vasomotor excitation and results in a decrease in the diameter of an artery during the chemoreceptor response to decreased blood pressure.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1905266	biolink:NamedThing	blasticidin S biosynthetic process	The chemical reactions and pathways resulting in the formation of blasticidin S.	tmpzr1t_l9r_go_relaxed.owl	blasticidin S anabolism|blasticidin S formation|blasticidin S biosynthesis|blasticidin S synthesis							pr	2016-06-14T12:47:22Z					biological_process											owl:Class	
GO:1905264	biolink:NamedThing	blasticidin S metabolic process	The chemical reactions and pathways involving blasticidin S.	tmpzr1t_l9r_go_relaxed.owl	blasticidin S metabolism							pr	2016-06-14T12:47:05Z					biological_process											owl:Class	
GO:0044500	biolink:NamedThing	envenomation resulting in negative regulation of blood pressure in other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant decrease of the force with which blood travels through the circulatory system of the bitten/stung organism.	tmpzr1t_l9r_go_relaxed.owl	hypotensive activity in other organism							jl	2012-02-01T02:40:50Z					biological_process											owl:Class	
GO:0044498	biolink:NamedThing	envenomation resulting in modulation of blood pressure in other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant modulation of the force with which blood travels through the circulatory system of the bitten/stung organism.	tmpzr1t_l9r_go_relaxed.owl	envenomation resulting in regulation of blood pressure in other organism							jl	2012-02-01T02:21:27Z					biological_process											owl:Class	
GO:1902972	biolink:NamedThing	premeiotic DNA replication DNA ligation	Any DNA ligation involved in meiotic cell cycle DNA replication.	tmpzr1t_l9r_go_relaxed.owl	DNA ligation involved in meiotic DNA replication|DNA ligation involved in meiotic cell cycle DNA replication							jl	2014-05-06T15:20:53Z					biological_process											owl:Class	
GO:1903593	biolink:NamedThing	regulation of histamine secretion by mast cell	Any process that modulates the frequency, rate or extent of histamine secretion by mast cell.	tmpzr1t_l9r_go_relaxed.owl								als	2014-11-06T13:19:09Z					biological_process											owl:Class	
GO:0062168	biolink:NamedThing	negative regulation of plus-end directed microtubule sliding	Any process that stops, prevents, or reduces the frequency, rate, or extent of plus-end directed microtubule sliding.	tmpzr1t_l9r_go_relaxed.owl								dph	2019-11-12T17:56:47Z					biological_process											owl:Class	
GO:0030548	biolink:NamedThing	acetylcholine receptor regulator activity	Interacting (directly or indirectly) with acetylcholine receptors such that the proportion of receptors in the active form is changed.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:2000610	biolink:NamedThing	negative regulation of thyroid hormone generation	Any process that stops, prevents or reduces the frequency, rate or extent of thyroid hormone generation.	tmpzr1t_l9r_go_relaxed.owl								yaf	2011-04-18T10:12:19Z					biological_process											owl:Class	
GO:0000314	biolink:NamedThing	organellar small ribosomal subunit	The smaller of the two subunits of an organellar ribosome.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0000291	biolink:NamedThing	nuclear-transcribed mRNA catabolic process, exonucleolytic	The chemical reactions and pathways resulting in the breakdown of the transcript body of a nuclear-transcribed mRNA that occurs when the ends are not protected by the 5'-cap or the 3'-poly(A) tail.	tmpzr1t_l9r_go_relaxed.owl	mRNA breakdown, exonucleolytic|nuclear mRNA catabolic process, exonucleolytic|mRNA degradation, exonucleolytic|exonucleolytic degradation of mRNA													biological_process											owl:Class	
GO:0035033	biolink:NamedThing	histone deacetylase regulator activity	Binds to and modulates the activity of histone deacetylase.	tmpzr1t_l9r_go_relaxed.owl						See also the molecular function term 'histone deacetylase activity ; GO:0004407'.								molecular_function											owl:Class	
GO:1990524	biolink:NamedThing	INA complex	A protein complex located in the inner membrane of mitochondria that is involved in the assembly of the peripheral (or stator) stalk of the mitochondrial proton-transporting ATP synthase (also known as the F1F0 ATP synthase). In budding yeast, this complex includes Ina22p and Ina17p.	tmpzr1t_l9r_go_relaxed.owl	INAC							jl	2014-11-03T16:03:39Z					cellular_component											owl:Class	
GO:0046157	biolink:NamedThing	siroheme catabolic process	The chemical reactions and pathways resulting in the breakdown of siroheme, a tetrahydroporphyrin with adjacent, reduced pyrrole rings.	tmpzr1t_l9r_go_relaxed.owl	siroheme degradation|sirohaem catabolic process|siroheme catabolism|siroheme breakdown|sirohaem catabolism													biological_process											owl:Class	
GO:0046156	biolink:NamedThing	siroheme metabolic process	The chemical reactions and pathways involving siroheme, a tetrahydroporphyrin with adjacent, reduced pyrrole rings.	tmpzr1t_l9r_go_relaxed.owl	sirohaem metabolism|siroheme metabolism|sirohaem metabolic process													biological_process											owl:Class	
GO:2001190	biolink:NamedThing	positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell	Any process that activates or increases the frequency, rate or extent of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of T lymphocyte activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell|positive regulation of T-lymphocyte activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell|positive regulation of T-cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell							yaf	2011-11-03T01:31:40Z					biological_process											owl:Class	
GO:0061168	biolink:NamedThing	regulation of hair follicle placode formation	Any process that modulates the rate, frequency, or extent of hair follicle placode formation, the developmental process in which a hair placode forms. An hair follicle placode is a thickening of the ectoderm that will give rise to the hair follicle bud.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-06-25T01:03:29Z					biological_process											owl:Class	
GO:0075315	biolink:NamedThing	positive regulation of basidium development	Any process that activates, maintains or increases the frequency, rate or extent of basidium development, a process that leads to the formation of basidium, a small, specialized club-shaped structure typically bearing four basidiospores at the tips of minute projections. The basidium is unique to basidiomycetes and distinguishes them from other kinds of fungi.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0075314	biolink:NamedThing	regulation of basidium development	Any process that modulates the frequency, rate or extent of basidium development, a process that leads to the formation of a basidium, a small, specialized club-shaped structure typically bearing four basidiospores at the tips of minute projections. The basidium is unique to Basidiomycetes and distinguishes them from other kinds of fungi.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0019576	biolink:NamedThing	aerobic fructose catabolic process	The chemical reactions and pathways resulting in the breakdown of fructose that occurs in the presence of oxygen.	tmpzr1t_l9r_go_relaxed.owl	aerobic fructose degradation|aerobic fructose catabolism|aerobic fructose breakdown													biological_process											owl:Class	
GO:0045689	biolink:NamedThing	negative regulation of antipodal cell differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of antipodal cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of antipodal cell differentiation|inhibition of antipodal cell differentiation|down regulation of antipodal cell differentiation|downregulation of antipodal cell differentiation													biological_process											owl:Class	
GO:1905724	biolink:NamedThing	positive regulation of trypanothione biosynthetic process	Any process that activates or increases the frequency, rate or extent of trypanothione biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of trypanothione anabolism|up regulation of trypanothione anabolism|positive regulation of trypanothione formation|upregulation of trypanothione biosynthetic process|up-regulation of trypanothione biosynthetic process|upregulation of trypanothione formation|activation of trypanothione anabolism|activation of trypanothione biosynthesis|positive regulation of trypanothione biosynthesis|activation of trypanothione synthesis|up-regulation of trypanothione formation|upregulation of trypanothione biosynthesis|positive regulation of trypanothione anabolism|up-regulation of trypanothione biosynthesis|up regulation of trypanothione synthesis|upregulation of trypanothione anabolism|up regulation of trypanothione biosynthesis|activation of trypanothione formation|up regulation of trypanothione biosynthetic process|upregulation of trypanothione synthesis|up-regulation of trypanothione synthesis|up regulation of trypanothione formation|positive regulation of trypanothione synthesis|activation of trypanothione biosynthetic process							rz	2016-11-25T14:44:50Z					biological_process											owl:Class	
GO:1905722	biolink:NamedThing	regulation of trypanothione biosynthetic process	Any process that modulates the frequency, rate or extent of trypanothione biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of trypanothione anabolism|regulation of trypanothione formation|regulation of trypanothione biosynthesis|regulation of trypanothione synthesis							rz	2016-11-25T14:44:34Z					biological_process											owl:Class	
GO:0002624	biolink:NamedThing	positive regulation of B cell antigen processing and presentation	Any process that activates or increases the frequency, rate, or extent of B cell antigen processing and presentation.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of B-lymphocyte antigen processing and presentation|upregulation of B cell antigen processing and presentation|positive regulation of B-cell antigen processing and presentation|up regulation of B cell antigen processing and presentation|positive regulation of B lymphocyte antigen processing and presentation|activation of B cell antigen processing and presentation|up-regulation of B cell antigen processing and presentation|stimulation of B cell antigen processing and presentation													biological_process											owl:Class	
GO:0097387	biolink:NamedThing	capitate projection	Simple or compound process of epithelial glial cells with a spherical head that inserts into photoreceptor axons. Capitate projections have only been observed in Brachycera (flies).	tmpzr1t_l9r_go_relaxed.owl								pr	2012-10-22T13:57:10Z					cellular_component											owl:Class	
GO:0097386	biolink:NamedThing	glial cell projection	A prolongation or process extending from a glial cell.	tmpzr1t_l9r_go_relaxed.owl	glial projection|glial process							pr	2012-10-22T13:55:54Z					cellular_component											owl:Class	
GO:0042487	biolink:NamedThing	regulation of odontogenesis of dentin-containing tooth	Any process that modulates the frequency, rate or extent of the formation and development of teeth, the hard, bony appendages which are borne on the jaws, or on other bones in the walls of the mouth or pharynx of most vertebrates.	tmpzr1t_l9r_go_relaxed.owl	regulation of odontogenesis of dentine-containing tooth|regulation of odontogenesis of dentine-containing teeth													biological_process											owl:Class	
GO:0021715	biolink:NamedThing	inferior olivary nucleus formation	The process that gives rise to the inferior olivary nucleus. This process pertains to the initial formation of a structure from unspecified parts. The inferior olivary nucleus is a capsule-shaped structure in the ventral medulla located just lateral and dorsal to the medullary pyramids. Neurons in the inferior olivary nucleus are the source of climbing fiber input to the cerebellar cortex; these neurons have been implicated in various functions, such as learning and timing of movements.	tmpzr1t_l9r_go_relaxed.owl	inferior olive biosynthesis|inferior olive formation													biological_process											owl:Class	
GO:0033909	biolink:NamedThing	fucoidanase activity	Catalysis of the endohydrolysis of 1,2-alpha-L-fucoside linkages in fucoidan without release of sulfate.	tmpzr1t_l9r_go_relaxed.owl	poly(1,2-alpha-L-fucoside-4-sulfate) glycanohydrolase activity				MetaCyc:RXN-20949|EC:3.2.1.211									molecular_function											owl:Class	
GO:0070809	biolink:NamedThing	negative regulation of Hulle cell development	Any process that stops, prevents, or reduces the frequency, rate or extent of Hulle cell development, a process that leads to the formation of Hulle cells. Hulle cells are specialized multinucleate cells that originate from a nest-like aggregation of hyphae during sexual development and serve as nurse cells to the developing cleistothecium, or fruiting body.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-07-08T04:53:11Z					biological_process											owl:Class	
GO:1905736	biolink:NamedThing	negative regulation of L-proline import across plasma membrane	Any process that stops, prevents or reduces the frequency, rate or extent of L-proline import across plasma membrane.	tmpzr1t_l9r_go_relaxed.owl								vw	2016-12-04T20:42:24Z					biological_process											owl:Class	
GO:0000160	biolink:NamedThing	phosphorelay signal transduction system	A conserved series of molecular signals found in prokaryotes and eukaryotes; involves autophosphorylation of a histidine kinase and the transfer of the phosphate group to an aspartate that then acts as a phospho-donor to response regulator proteins.	tmpzr1t_l9r_go_relaxed.owl	histidyl-aspartyl phosphorelay													biological_process											owl:Class	
GO:0001408	biolink:NamedThing	guanine nucleotide transport	The directed movement of guanine nucleotides, GTP, GDP, and/or GMP, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0015865	biolink:NamedThing	purine nucleotide transport	The directed movement of a purine nucleotide, any compound consisting of a purine nucleoside esterified with (ortho)phosphate, into, out of or within a cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0031231	biolink:NamedThing	intrinsic component of peroxisomal membrane	The component of the peroxisomal membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.	tmpzr1t_l9r_go_relaxed.owl	intrinsic to peroxisomal membrane													cellular_component											owl:Class	
GO:0032208	biolink:NamedThing	negative regulation of telomere maintenance via recombination	Any process that stops, prevents, or reduces the frequency, rate or extent of a recombinational process involved in the maintenance of proper telomeric length.	tmpzr1t_l9r_go_relaxed.owl	down regulation of telomere maintenance via recombination|downregulation of telomere maintenance via recombination|inhibition of telomere maintenance via recombination|down-regulation of telomere maintenance via recombination													biological_process											owl:Class	
GO:0032207	biolink:NamedThing	regulation of telomere maintenance via recombination	Any process that modulates the frequency, rate or extent of a recombinational process involved in the maintenance of proper telomeric length.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1901942	biolink:NamedThing	(+)-epi-alpha-bisabolol catabolic process	The chemical reactions and pathways resulting in the breakdown of (+)-epi-alpha-bisabolol.	tmpzr1t_l9r_go_relaxed.owl	(+)-epi-alpha-bisabolol catabolism|(+)-epi-alpha-bisabolol degradation|(+)-epi-alpha-bisabolol breakdown							ms	2013-02-18T14:55:41Z					biological_process											owl:Class	
GO:0016107	biolink:NamedThing	sesquiterpenoid catabolic process	The chemical reactions and pathways resulting in the breakdown of sesquiterpenoid compounds, terpenoids with three isoprene units.	tmpzr1t_l9r_go_relaxed.owl	sesquiterpenoid degradation|sesquiterpenoid breakdown|sesquiterpenoid catabolism													biological_process											owl:Class	
GO:0046501	biolink:NamedThing	protoporphyrinogen IX metabolic process	The chemical reactions and pathways involving protoporphyrinogen IX, the specific substrate for the enzyme ferrochelatase, which catalyzes the insertion of iron to form protoheme. It is probably also the substrate for chlorophyll formation.	tmpzr1t_l9r_go_relaxed.owl	protoporphyrinogen IX metabolism					See also the molecular function term 'ferrochelatase activity ; GO:0004325'.								biological_process											owl:Class	
GO:0006778	biolink:NamedThing	porphyrin-containing compound metabolic process	The chemical reactions and pathways involving any member of a large group of derivatives or analogs of porphyrin. Porphyrins consists of a ring of four pyrrole nuclei linked each to the next at their alpha positions through a methine group.	tmpzr1t_l9r_go_relaxed.owl	porphyrin metabolic process|porphyrin metabolism													biological_process											owl:Class	
GO:0043671	biolink:NamedThing	endexine	The inner part of the exine, which stains.	tmpzr1t_l9r_go_relaxed.owl						Note that endexine is distinguished on staining properties; compare with 'sexine ; GO:0043673'. See also 'ectexine ; GO:0043669'.								cellular_component											owl:Class	
GO:0080163	biolink:NamedThing	regulation of protein serine/threonine phosphatase activity	Any process that modulates the frequency, rate or extent of protein serine/threonine phosphatase activity: catalysis of the reaction: protein serine/threonine phosphate + H2O = protein serine/threonine + phosphate.	tmpzr1t_l9r_go_relaxed.owl	regulation of protein phosphatase type 2c activity							dhl	2010-09-23T03:51:37Z					biological_process											owl:Class	
GO:0043666	biolink:NamedThing	regulation of phosphoprotein phosphatase activity	Any process that modulates the frequency, rate or extent of phosphoprotein phosphatase activity, the catalysis of the hydrolysis of phosphate from a phosphoprotein.	tmpzr1t_l9r_go_relaxed.owl	regulation of protein phosphatase type 2A activity|regulation of protein phosphatase type 2B activity|regulation of calcineurin activity|regulation of protein phosphatase type 2 activity|regulation of protein phosphatase 3 activity											GO:0034047|GO:0032512		biological_process											owl:Class	
GO:0102440	biolink:NamedThing	3',4',5'-trimethylmyricetin 3-O-methyltransferase activity	Catalysis of the reaction: 3',4',5'-trimethylmyricetin + S-adenosyl-L-methionine  <=> 3,3',4',5'-tetramethylmyricetin + S-adenosyl-L-homocysteine  + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-13918									molecular_function											owl:Class	
GO:0106045	biolink:NamedThing	guanine deglycation, methylglyoxal removal	The removal of methylglyoxal from a glycated guanine, to form lactate and a deglycated guanine.	tmpzr1t_l9r_go_relaxed.owl								hjd	2017-08-01T18:17:28Z					biological_process											owl:Class	
GO:0140041	biolink:NamedThing	cellular detoxification of methylglyoxal	Any process carried out at the cellular level that reduces or removes the toxicity of methylglyoxal.	tmpzr1t_l9r_go_relaxed.owl								pg	2017-06-16T09:43:30Z					biological_process											owl:Class	
GO:1903743	biolink:NamedThing	negative regulation of anterograde synaptic vesicle transport	Any process that stops, prevents or reduces the frequency, rate or extent of anterograde synaptic vesicle transport.	tmpzr1t_l9r_go_relaxed.owl	down regulation of anterograde synaptic vesicle transport|down-regulation of anterograde synaptic vesicle transport|downregulation of anterograde synaptic vesicle transport|inhibition of anterograde synaptic vesicle transport							kmv	2014-12-12T16:28:37Z					biological_process											owl:Class	
GO:0048390	biolink:NamedThing	intermediate mesoderm morphogenesis	The process in which the anatomical structures of the intermediate mesoderm are generated and organized.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1901597	biolink:NamedThing	response to carbendazim	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbendazim stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2012-11-07T17:17:06Z					biological_process											owl:Class	
GO:0002716	biolink:NamedThing	negative regulation of natural killer cell mediated immunity	Any process that stops, prevents, or reduces the frequency, rate, or extent of natural killer cell mediated immunity.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of natural killer cell activity|down-regulation of natural killer cell mediated immunity|inhibition of natural killer cell mediated immunity|down regulation of natural killer cell mediated immunity|negative regulation of NK cell activity|negative regulation of NK cell mediated immunity|downregulation of natural killer cell mediated immunity											GO:0030102		biological_process											owl:Class	
GO:0016035	biolink:NamedThing	zeta DNA polymerase complex	A heterodimeric DNA polymerase complex that catalyzes error-prone DNA synthesis in contexts such as translesion synthesis and double-stranded break repair. First characterized in Saccharomyces, in which the subunits are Rev3p and Rev7p; a third protein, Rev1p, is often associated with the polymerase dimer.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0032441	biolink:NamedThing	pheophorbide a oxygenase activity	Catalysis of the reaction: pheophorbide a + reduced ferredoxin + 2 O2 = red chlorophyll catabolite + oxidized ferredoxin + H2O.	tmpzr1t_l9r_go_relaxed.owl					RHEA:48140|EC:1.14.15.17|MetaCyc:RXN-7740									molecular_function											owl:Class	
GO:0016730	biolink:NamedThing	oxidoreductase activity, acting on iron-sulfur proteins as donors	Catalysis of an oxidation-reduction (redox) reaction in which an iron-sulfur protein acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.	tmpzr1t_l9r_go_relaxed.owl	oxidoreductase activity, acting on iron-sulphur proteins as donors				EC:1.18.-.-									molecular_function											owl:Class	
GO:0042716	biolink:NamedThing	plasma membrane-derived chromatophore	A pigment-bearing structure that is derived from the cytoplasmic membrane, sometimes consisting of simple invaginations and sometimes a complete vesicle. This component is found in certain photosynthetic bacteria and cyanobacteria.	tmpzr1t_l9r_go_relaxed.owl	chromatophore vesicle					Note that this structure is distinct from the chromoplast of plants, which is also sometimes called a chromatophore; it also should not be confused with the specialized pigment-producing cells known as chromatophores, found in fish and amphibian skin.								cellular_component											owl:Class	
GO:0072731	biolink:NamedThing	cellular response to papulacandin B	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a papulacandin B stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2012-05-31T11:30:39Z					biological_process											owl:Class	
GO:0047240	biolink:NamedThing	lactosylceramide beta-1,3-galactosyltransferase activity	Catalysis of the reaction: D-galactosyl-(1->4)-beta-D-glucosyl-R + UDP-D-galactose = D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-R + H(+) + UDP.	tmpzr1t_l9r_go_relaxed.owl	UDP-galactose:D-galactosyl-1,4-beta-D-glucosyl-R beta-1,3-galactosyltransferase activity|UDPgalactose:D-galactosyl-1,4-beta-D-glucosyl-R beta-1,3-galactosyltransferase activity|uridine diphosphogalactose-lactosylceramide beta1->3-galactosyltransferase activity				MetaCyc:2.4.1.179-RXN|RHEA:18413|KEGG_REACTION:R04431|EC:2.4.1.179									molecular_function											owl:Class	
GO:0140592	biolink:NamedThing	histone methyltransferase activity (H3-R8 specific)	Catalysis of the reaction: S-adenosyl-L-methionine + (histone H3)-arginine (position 8) = S-adenosyl-L-homocysteine + (histone H3-N-methyl-arginine (position 8). This reaction is the addition of a methyl group to arginine at position 8 of histone H3.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/20037						pg	2021-02-09T14:13:17Z					molecular_function											owl:Class	
GO:0015775	biolink:NamedThing	beta-glucan transport	The directed movement of beta-glucans into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Beta-glucans are compounds composed of glucose residues linked by beta-glucosidic bonds.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0015774	biolink:NamedThing	polysaccharide transport	The directed movement of polysaccharides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A polysaccharide is a polymer of many (typically more than 10) monosaccharide residues linked glycosidically.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0015550	biolink:NamedThing	galacturonate transmembrane transporter activity	Enables the transfer of galacturonate from one side of a membrane to the other. Galacturonate is the uronic acid formally derived from galactose by oxidation of the hydroxymethylene group at C-6 to a carboxyl group.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0102082	biolink:NamedThing	demethylrebeccamycin--D-glucose O-methyltransferase activity	Catalysis of the reaction: 4'-demethylrebeccamycin + S-adenosyl-L-methionine  <=> H+ + rebeccamycin + S-adenosyl-L-homocysteine.	tmpzr1t_l9r_go_relaxed.owl					RHEA:27353|EC:2.1.1.164|MetaCyc:RXN-10847									molecular_function											owl:Class	
GO:1900459	biolink:NamedThing	positive regulation of brassinosteroid mediated signaling pathway	Any process that activates or increases the frequency, rate or extent of brassinosteroid mediated signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of brassinosteroid mediated signalling|activation of brassinosteroid mediated signaling pathway|up-regulation of brassinosteroid mediated signaling pathway|up-regulation of brassinosteroid mediated signalling|up regulation of brassinosteroid mediated signaling pathway|activation of brassinosteroid mediated signalling|upregulation of brassinosteroid mediated signaling pathway|upregulation of brassinosteroid mediated signalling|up regulation of brassinosteroid mediated signalling							dhl	2012-05-01T06:12:23Z					biological_process											owl:Class	
GO:1900457	biolink:NamedThing	regulation of brassinosteroid mediated signaling pathway	Any process that modulates the frequency, rate or extent of brassinosteroid mediated signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	regulation of brassinosteroid mediated signalling							dhl	2012-05-01T06:12:04Z					biological_process											owl:Class	
GO:0140352	biolink:NamedThing	export from cell	The directed movement of some substance from a cell, into the extracellular region. This may occur via transport across the plasma membrane or via exocytosis.	tmpzr1t_l9r_go_relaxed.owl	efflux							pg	2019-05-22T11:20:45Z					biological_process											owl:Class	
GO:0003354	biolink:NamedThing	negative regulation of cilium movement	Any process that decreases the rate, frequency, or extent of cilium movement, the directed, self-propelled movement of a cilium.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of microtubule-based flagellum movement|negative regulation of flagellum movement					Note that we deem cilium and microtubule-based flagellum to be equivalent.		dph	2009-12-03T10:17:47Z			GO:1900173		biological_process											owl:Class	
GO:1903763	biolink:NamedThing	gap junction channel activity involved in cell communication by electrical coupling	Any gap junction channel activity that is involved in cell communication by electrical coupling.	tmpzr1t_l9r_go_relaxed.owl	connexin involved in cell communication by electrical coupling|innexin involved in cell communication by electrical coupling|innexin channel activity involved in cell communication by electrical coupling							rl	2014-12-19T15:43:16Z					molecular_function											owl:Class	
GO:0008454	biolink:NamedThing	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity	Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + (N-acetyl-beta-D-glucosaminyl-1,2)-alpha-D-mannosyl-1,3-(beta-N-acetyl-D-glucosaminyl-1,2-alpha-D-mannosyl-1,6)-beta-D-mannosyl-R = UDP + N-acetyl-beta-D-glucosaminyl-1,4-(N-acetyl-D-glucosaminyl-1,2)-alpha-D-mannosyl-1,3-(beta-N-acetyl-D-glucosaminyl-1,2-alpha-D-mannosyl-1,6)-beta-D-mannosyl-R.	tmpzr1t_l9r_go_relaxed.owl	uridine diphosphoacetylglucosamine-glycopeptide beta-4-acetylglucosaminyltransferase IV activity|alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase activity|uridine diphosphoacetylglucosamine-glycopeptide beta4-acetylglucosaminyltransferase IV|UDP-N-acetyl-D-glucosamine:3-[2-(N-acetyl-beta-D-glucosaminyl)-alpha-D-mannosyl]-glycoprotein 4-beta-N-acetyl-D-glucosaminyltransferase activity|N-acetylglucosaminyltransferase IV activity|N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase IV activity|GnTIV activity|beta-acetylglucosaminyltransferase IV activity|alpha-1,3-mannosylglycoprotein beta-1,4-N-acetylglucosaminyltransferase activity				Reactome:R-HSA-975903|EC:2.4.1.145|RHEA:16057|Reactome:R-HSA-9696980|MetaCyc:2.4.1.145-RXN									molecular_function											owl:Class	
GO:0034286	biolink:NamedThing	response to maltose	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a maltose stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to maltose stimulus													biological_process											owl:Class	
GO:0043076	biolink:NamedThing	megasporocyte nucleus	The nucleus of a megasporocyte, a diploid cell that undergoes meiosis to produce four megaspores, and its descendents.	tmpzr1t_l9r_go_relaxed.owl	megaspore mother cell nucleus													cellular_component											owl:Class	
GO:1901454	biolink:NamedThing	regulation of response to toluene	Any process that modulates the frequency, rate or extent of response to toluene.	tmpzr1t_l9r_go_relaxed.owl								tt	2012-10-02T14:22:17Z					biological_process											owl:Class	
GO:0008888	biolink:NamedThing	glycerol dehydrogenase [NAD+] activity	Catalysis of the reaction: glycerol + NAD(+) = glycerone + H(+) + NADH.	tmpzr1t_l9r_go_relaxed.owl	NAD-linked glycerol dehydrogenase activity|glycerol dehydrogenase activity				KEGG_REACTION:R01034|RHEA:13769|MetaCyc:GLYCDEH-RXN|EC:1.1.1.6									molecular_function											owl:Class	
GO:0015056	biolink:NamedThing	corticotrophin-releasing factor receptor activity	Combining with the corticotrophin-releasing factor family of ligands, including the urocortins, to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1900573	biolink:NamedThing	emodin metabolic process	The chemical reactions and pathways involving emodin.	tmpzr1t_l9r_go_relaxed.owl	emodin metabolism							di	2012-05-15T06:41:44Z					biological_process											owl:Class	
GO:1903848	biolink:NamedThing	negative regulation of aorta morphogenesis	Any process that stops, prevents or reduces the frequency, rate or extent of aorta morphogenesis.	tmpzr1t_l9r_go_relaxed.owl	inhibition of aorta morphogenesis|down regulation of aorta morphogenesis|down-regulation of aorta morphogenesis|downregulation of aorta morphogenesis							rph	2015-01-23T14:01:01Z					biological_process											owl:Class	
GO:1903847	biolink:NamedThing	regulation of aorta morphogenesis	Any process that modulates the frequency, rate or extent of aorta morphogenesis.	tmpzr1t_l9r_go_relaxed.owl								rph	2015-01-23T14:00:51Z					biological_process											owl:Class	
GO:0017187	biolink:NamedThing	peptidyl-glutamic acid carboxylation	The gamma-carboxylation of peptidyl-glutamic acid; catalyzed by the vitamin K dependent gamma-glutamyl carboxylase.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0032	See also the molecular function term 'gamma-glutamyl carboxylase activity ; GO:0008488'.								biological_process											owl:Class	
GO:1900065	biolink:NamedThing	regulation of ethanol catabolic process	Any process that modulates the frequency, rate or extent of ethanol catabolic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of ethanol degradation|regulation of ethanol breakdown|regulation of ethanol catabolism							dph	2012-01-26T01:51:40Z					biological_process											owl:Class	
GO:1902387	biolink:NamedThing	ceramide 1-phosphate binding	Binding to ceramide 1-phosphate.	tmpzr1t_l9r_go_relaxed.owl								uh	2013-09-05T05:51:08Z					molecular_function											owl:Class	
GO:0072269	biolink:NamedThing	metanephric long descending thin limb development	The process whose specific outcome is the progression of the metanephric long descending thin limb over time, from its formation to the mature structure. The metanephric long descending thin limb is the descending thin limb of a long nephron in the metanephros that has a squamous epithelial morphology. The long descending limb starts in the inner stripe of the outer medulla and extends into the inner medulla.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-03-30T03:12:05Z					biological_process											owl:Class	
GO:0072064	biolink:NamedThing	long descending thin limb development	The process whose specific outcome is the progression of the long descending thin limb over time, from its formation to the mature structure. The long descending thin limb is the descending thin limb of a long nephron that has a squamous epithelial morphology. The long descending limb starts in the inner stripe of the outer medulla and extends into the inner medulla.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-01-25T04:13:17Z					biological_process											owl:Class	
GO:0030150	biolink:NamedThing	protein import into mitochondrial matrix	The import of proteins across the outer and inner mitochondrial membranes into the matrix. Unfolded proteins enter the mitochondrial matrix with a chaperone protein; the information required to target the precursor protein from the cytosol to the mitochondrial matrix is contained within its N-terminal matrix-targeting sequence. Translocation of precursors to the matrix occurs at the rare sites where the outer and inner membranes are close together.	tmpzr1t_l9r_go_relaxed.owl	mitochondrial translocation|protein transport into mitochondrial matrix|mitochondrial matrix protein import													biological_process											owl:Class	
GO:0006839	biolink:NamedThing	mitochondrial transport	Transport of substances into, out of or within a mitochondrion.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/22316												biological_process											owl:Class	
GO:0090093	biolink:NamedThing	regulation of fungal-type cell wall beta-glucan biosynthetic process	Any process that modulates the frequency, rate or extent of fungal-type cell wall beta-glucan biosynthesis, the chemical reactions and pathways resulting in the formation of beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds, found in the walls of fungal cells.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-11-13T10:10:38Z					biological_process											owl:Class	
GO:0075282	biolink:NamedThing	negative regulation of uredinium development	Any process that stops, prevents, or reduces the frequency, rate or extent of uredinium development, a process that leads to the formation of a reddish, pustule-like structure formed by a rust fungus and consisting of uredospores.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0046636	biolink:NamedThing	negative regulation of alpha-beta T cell activation	Any process that stops, prevents, or reduces the frequency, rate or extent of alpha-beta T cell activation.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of alpha-beta T cell activation|down regulation of alpha-beta T cell activation|negative regulation of alpha-beta T-cell activation|negative regulation of alpha-beta T-lymphocyte activation|inhibition of alpha-beta T cell activation|negative regulation of alpha-beta T lymphocyte activation|downregulation of alpha-beta T cell activation													biological_process											owl:Class	
GO:0033731	biolink:NamedThing	arogenate dehydrogenase [NAD(P)+] activity	Catalysis of the reaction: L-arogenate + NAD(P)+ = L-tyrosine + NAD(P)H + CO2.	tmpzr1t_l9r_go_relaxed.owl	arogenic dehydrogenase activity|pretyrosine dehydrogenase activity|L-arogenate:NAD(P)+ oxidoreductase (decarboxylating) activity				MetaCyc:1.3.1.79-RXN|EC:1.3.1.79									molecular_function											owl:Class	
GO:0060994	biolink:NamedThing	regulation of transcription from RNA polymerase II promoter involved in kidney development	Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the branching morphogenesis by which the kidney progresses from its initial formation to the mature state.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-01-19T08:24:46Z					biological_process											owl:Class	
GO:1900451	biolink:NamedThing	positive regulation of glutamate receptor signaling pathway	Any process that activates or increases the frequency, rate or extent of glutamate receptor signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of glutamate signaling pathway|upregulation of glutamate receptor signaling pathway|positive regulation of glutamate signalling pathway|up regulation of glutamate receptor signaling pathway|activation of glutamate signalling pathway|activation of glutamate receptor signaling pathway|activation of glutamate signaling pathway|up regulation of glutamate signaling pathway|up regulation of glutamate signalling pathway|up-regulation of glutamate receptor signaling pathway|upregulation of glutamate signaling pathway|up-regulation of glutamate signalling pathway|up-regulation of glutamate signaling pathway|upregulation of glutamate signalling pathway							rl	2012-04-27T03:46:03Z					biological_process											owl:Class	
GO:0009196	biolink:NamedThing	pyrimidine deoxyribonucleoside diphosphate metabolic process	The chemical reactions and pathways involving pyrimidine deoxynucleoside diphosphate, a compound consisting of a pyrimidine base linked to a deoxyribose sugar esterified with diphosphate on the sugar.	tmpzr1t_l9r_go_relaxed.owl	pyrimidine deoxyribonucleoside diphosphate metabolism													biological_process											owl:Class	
GO:0010373	biolink:NamedThing	negative regulation of gibberellin biosynthetic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of gibberellins.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of gibberellic acid biosynthetic process													biological_process											owl:Class	
GO:0045827	biolink:NamedThing	negative regulation of isoprenoid metabolic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving isoprenoid.	tmpzr1t_l9r_go_relaxed.owl	inhibition of isoprenoid metabolic process|down regulation of isoprenoid metabolic process|downregulation of isoprenoid metabolic process|negative regulation of isoprenoid metabolism|down-regulation of isoprenoid metabolic process													biological_process											owl:Class	
GO:0018085	biolink:NamedThing	peptidyl-L-amino acid racemization	The process of conversion of a L-amino acid into its enantiomer, the corresponding D-amino acid.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1905539	biolink:NamedThing	regulation of postsynapse to nucleus signaling pathway	Any process that modulates the frequency, rate or extent of postsynapse to nucleus signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	regulation of postsynaptic signaling to nucleus							dos	2016-10-07T17:03:38Z					biological_process											owl:Class	
GO:0061950	biolink:NamedThing	negative regulation of premature acrosome loss	Any process that stops, prevents or reduces the discharge, by sperm, of a single, anterior secretory granule before the sperm reaches to the zona pellucida of the oocyte. The process begins with the fusion of the outer acrosomal membrane with the sperm plasma membrane and ends with the exocytosis of the acrosomal contents.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of spontaneous acrosome loss							dph	2017-10-25T17:56:47Z					biological_process											owl:Class	
GO:0007073	biolink:NamedThing	positive regulation of transcription involved in exit from mitosis, from RNA polymerase I promoter	Any process that increases the frequency, rate or extent of transcription from an RNA polymerase I promoter as the cell leaves M phase. M phase is the part of the mitotic cell cycle during which mitosis and cytokinesis take place.	tmpzr1t_l9r_go_relaxed.owl	activation of transcription on exit from mitosis, from RNA polymerase I promoter|activation of transcription on exit from mitosis, from Pol I promoter													biological_process											owl:Class	
GO:0007072	biolink:NamedThing	positive regulation of transcription involved in exit from mitosis	Any process that increases the frequency, rate or extent of transcription as the cell leaves M phase. M phase is the part of the mitotic cell cycle during which mitosis and cytokinesis take place.	tmpzr1t_l9r_go_relaxed.owl	activation of transcription on exit from mitosis													biological_process											owl:Class	
GO:0010450	biolink:NamedThing	inflorescence meristem growth	The increase in size or mass of an inflorescence meristem, a population of undifferentiated cells in a plant shoot which produces small leaves and then floral meristems, which will give rise to flowers.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0043315	biolink:NamedThing	positive regulation of neutrophil degranulation	Any process that activates or increases the frequency, rate or extent of neutrophil degranulation.	tmpzr1t_l9r_go_relaxed.owl	up regulation of neutrophil degranulation|up-regulation of neutrophil degranulation|activation of neutrophil degranulation|positive regulation of neutrophil granule exocytosis|stimulation of neutrophil degranulation|upregulation of neutrophil degranulation													biological_process											owl:Class	
GO:0030678	biolink:NamedThing	mitochondrial ribonuclease P complex	A ribonuclease P complex located in the mitochondrion of a eukaryotic cell, where it catalyzes the 5' endonucleolytic cleavage of precursor tRNAs to yield mature tRNAs. The subunit composition of mitochondrial ribonuclease P complexes varies between species. The complex contains a single RNA molecule and a single protein molecule in yeast (PMID:12045094), but comprises three proteins and lacks an RNA component in humans.	tmpzr1t_l9r_go_relaxed.owl	mitochondrial RNase P complex	https://github.com/geneontology/go-ontology/issues/20778												cellular_component											owl:Class	
GO:0098798	biolink:NamedThing	mitochondrial protein-containing complex	A protein complex that is part of a mitochondrion.	tmpzr1t_l9r_go_relaxed.owl	mitochondrial protein complex					Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.								cellular_component											owl:Class	
GO:1903068	biolink:NamedThing	positive regulation of protein localization to cell tip	Any process that activates or increases the frequency, rate or extent of protein localization to cell tip.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of protein localisation to cell tip|activation of protein localization to cell tip|up-regulation of protein localization to cell tip|positive regulation of protein localisation to cell tip|upregulation of protein localisation to cell tip|up regulation of protein localization to cell tip|upregulation of protein localization to cell tip|up regulation of protein localisation to cell tip|activation of protein localisation to cell tip							vw	2014-05-28T15:48:54Z					biological_process											owl:Class	
GO:1903066	biolink:NamedThing	regulation of protein localization to cell tip	Any process that modulates the frequency, rate or extent of protein localization to cell tip.	tmpzr1t_l9r_go_relaxed.owl	regulation of protein localisation to cell tip							vw	2014-05-28T15:48:42Z					biological_process											owl:Class	
GO:0018057	biolink:NamedThing	peptidyl-lysine oxidation	The oxidation of the terminal amino-methylene groups of peptidyl-L-lysine or peptidyl-5-hydroxy-L-lysine to aldehyde groups to form allysine or hydroxyallysine residues, respectively; these are intermediates in the formation of covalent cross-links between adjacent polypeptide chains in proteins such as collagens.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0121									biological_process											owl:Class	
GO:0070107	biolink:NamedThing	regulation of interleukin-27-mediated signaling pathway	Any process that modulates the rate, frequency or extent of the series of molecular events generated as a consequence of interleukin-27-mediated binding to a cell surface receptor.	tmpzr1t_l9r_go_relaxed.owl	regulation of IL27RA/IL6ST signaling pathway|regulation of IL-27-mediated signaling pathway|regulation of interleukin-27-mediated signalling pathway													biological_process											owl:Class	
GO:0044223	biolink:NamedThing	pirellulosome	A cytoplasmic structure found in bacterial phyla Planctomycetes and Verrucomicrobia containing a condensed nucleoid and ribosomes and surrounded by an intracytoplasmic membrane. It is surrounded by ribosome-free cytoplasm, in a compartment called the paryphoplasm.	tmpzr1t_l9r_go_relaxed.owl								jl	2009-11-12T04:08:07Z					cellular_component											owl:Class	
GO:0042702	biolink:NamedThing	uterine wall growth	The regrowth of the endometrium and blood vessels in the uterus following menstruation, resulting from a rise in progesterone levels.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1900683	biolink:NamedThing	regulation of fumonisin biosynthetic process	Any process that modulates the frequency, rate or extent of fumonisin biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of fumonisin synthesis|regulation of fumonisin formation|regulation of fumonisin anabolism|regulation of fumonisin biosynthesis							di	2012-05-22T04:29:38Z					biological_process											owl:Class	
GO:0042886	biolink:NamedThing	amide transport	The directed movement of an amide, any compound containing one, two, or three acyl groups attached to a nitrogen atom, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0070960	biolink:NamedThing	positive regulation of neutrophil mediated cytotoxicity	Any process that increases the frequency, rate or extent of the directed killing of a target cell by a neutrophil.	tmpzr1t_l9r_go_relaxed.owl	activation of neutrophil mediated cytotoxicity|up-regulation of neutrophil mediated cytotoxicity|stimulation of neutrophil mediated cytotoxicity|upregulation of neutrophil mediated cytotoxicity|positive regulation of neutrophil mediated cell killing|up regulation of neutrophil mediated cytotoxicity							mah	2009-10-01T02:28:49Z					biological_process											owl:Class	
GO:1902808	biolink:NamedThing	positive regulation of cell cycle G1/S phase transition	Any signalling pathway that activates or increases the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G1 phase to S phase of the cell cycle.	tmpzr1t_l9r_go_relaxed.owl	activation of cell cycle G1/S phase transition|up regulation of cell cycle G1/S phase transition|up-regulation of cell cycle G1/S phase transition|upregulation of cell cycle G1/S phase transition							jl	2014-03-26T16:36:32Z					biological_process											owl:Class	
GO:1900232	biolink:NamedThing	negative regulation of single-species biofilm formation on inanimate substrate	Any process that stops, prevents or reduces the frequency, rate or extent of single-species biofilm formation on inanimate substrate.	tmpzr1t_l9r_go_relaxed.owl	down regulation of single-species biofilm formation on inanimate substrate|downregulation of single-species biofilm formation on inanimate substrate|down-regulation of single-species biofilm formation on inanimate substrate|inhibition of single-species biofilm formation on inanimate substrate							di	2012-03-23T04:40:45Z					biological_process											owl:Class	
GO:1900859	biolink:NamedThing	negative regulation of brevianamide F biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of brevianamide F biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	down regulation of brevianamide F biosynthetic process|down-regulation of brevianamide F biosynthetic process|downregulation of brevianamide F biosynthetic process							di	2012-06-07T09:53:17Z					biological_process											owl:Class	
GO:0006096	biolink:NamedThing	glycolytic process	The chemical reactions and pathways resulting in the breakdown of a carbohydrate into pyruvate, with the concomitant production of a small amount of ATP and the reduction of NAD(P) to NAD(P)H. Glycolysis begins with the metabolism of a carbohydrate to generate products that can enter the pathway and ends with the production of pyruvate. Pyruvate may be converted to acetyl-coenzyme A, ethanol, lactate, or other small molecules.	tmpzr1t_l9r_go_relaxed.owl	modifed Embden-Meyerhof pathway|Embden-Meyerhof-Parnas pathway|Embden-Meyerhof pathway|anaerobic glycolysis|glycolysis				MetaCyc:GLYCOLYSIS-VARIANTS							GO:0019642|GO:0019641		biological_process											owl:Class	
GO:0102864	biolink:NamedThing	1-18:3-2-18:2-phosphatidylcholine desaturase activity	Catalysis of the reaction: 1-18:3-2-18:2-phosphatidylcholine + O2 + a reduced electron acceptor <=> 1-18:3-2-18:3-phosphatidylcholine + 2 H2O + an oxidized electron acceptor.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-8331									molecular_function											owl:Class	
GO:1904775	biolink:NamedThing	positive regulation of ubiquinone biosynthetic process	Any process that activates or increases the frequency, rate or extent of ubiquinone biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of ubiquinone anabolism|positive regulation of ubiquinone anabolism|up regulation of coenzyme Q10 biosynthetic process|positive regulation of ubiquinone biosynthesis|upregulation of coenzyme Q biosynthesis|up-regulation of ubiquinone synthesis|positive regulation of coenzyme Q6 biosynthesis|positive regulation of coenzyme Q biosynthesis|upregulation of coenzyme Q10 biosynthesis|positive regulation of coenzyme Q9 biosynthesis|upregulation of coenzyme Q6 biosynthetic process|up regulation of ubiquinone biosynthesis|activation of ubiquinone formation|upregulation of coenzyme Q8 biosynthetic process|activation of coenzyme Q8 biosynthesis|up-regulation of ubiquinone formation|up-regulation of coenzyme Q6 biosynthesis|positive regulation of coenzyme Q biosynthetic process|up regulation of coenzyme Q8 biosynthesis|up-regulation of coenzyme Q10 biosynthetic process|upregulation of ubiquinone formation|up-regulation of coenzyme Q10 biosynthesis|activation of coenzyme Q9 biosynthesis|activation of coenzyme Q10 biosynthetic process|activation of coenzyme Q6 biosynthesis|activation of coenzyme Q9 biosynthetic process|activation of ubiquinone biosynthetic process|up-regulation of coenzyme Q8 biosynthesis|activation of coenzyme Q biosynthetic process|up-regulation of coenzyme Q6 biosynthetic process|up-regulation of ubiquinone biosynthetic process|positive regulation of ubiquinone formation|up regulation of coenzyme Q biosynthetic process|positive regulation of coenzyme Q6 biosynthetic process|activation of coenzyme Q biosynthesis|activation of ubiquinone biosynthesis|up regulation of coenzyme Q8 biosynthetic process|positive regulation of coenzyme Q10 biosynthetic process|up-regulation of coenzyme Q9 biosynthesis|upregulation of ubiquinone synthesis|upregulation of coenzyme Q9 biosynthetic process|up-regulation of coenzyme Q biosynthetic process|up regulation of coenzyme Q6 biosynthesis|upregulation of coenzyme Q10 biosynthetic process|up regulation of coenzyme Q10 biosynthesis|up regulation of coenzyme Q9 biosynthesis|up regulation of ubiquinone synthesis|up regulation of ubiquinone formation|positive regulation of coenzyme Q9 biosynthetic process|upregulation of ubiquinone anabolism|activation of coenzyme Q8 biosynthetic process|activation of coenzyme Q6 biosynthetic process|up-regulation of coenzyme Q biosynthesis|up-regulation of coenzyme Q8 biosynthetic process|up regulation of coenzyme Q biosynthesis|upregulation of ubiquinone biosynthetic process|up-regulation of coenzyme Q9 biosynthetic process|activation of ubiquinone synthesis|upregulation of ubiquinone biosynthesis|positive regulation of coenzyme Q8 biosynthesis|positive regulation of ubiquinone synthesis|up-regulation of ubiquinone biosynthesis|positive regulation of coenzyme Q10 biosynthesis|upregulation of coenzyme Q9 biosynthesis|upregulation of coenzyme Q6 biosynthesis|up regulation of coenzyme Q6 biosynthetic process|positive regulation of coenzyme Q8 biosynthetic process|activation of coenzyme Q10 biosynthesis|up regulation of ubiquinone anabolism|upregulation of coenzyme Q8 biosynthesis|activation of ubiquinone anabolism|up regulation of coenzyme Q9 biosynthetic process|upregulation of coenzyme Q biosynthetic process|up regulation of ubiquinone biosynthetic process							sl	2015-10-28T21:21:26Z					biological_process											owl:Class	
GO:0010788	biolink:NamedThing	COPI coating of Golgi vesicle, cis-Golgi to rough ER	The addition of COPI proteins and adaptor proteins to Golgi membranes during the formation of cis-Golgi to rough ER transport vesicles, forming a vesicle coat.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0048205	biolink:NamedThing	COPI coating of Golgi vesicle	The addition of COPI proteins and adaptor proteins to Golgi membranes during the formation of transport vesicles, forming a vesicle coat.	tmpzr1t_l9r_go_relaxed.owl	COPI coating of Golgi-derived vesicle|COPI vesicle coating													biological_process											owl:Class	
GO:0035604	biolink:NamedThing	fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow	The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands, which activates or increases the frequency, rate or extent of cell proliferation in the bone marrow.	tmpzr1t_l9r_go_relaxed.owl	fibroblast growth factor receptor signalling pathway involved in positive regulation of cell proliferation in bone marrow|FGFR signaling pathway involved in positive regulation of cell proliferation in bone marrow|FGF receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow							bf	2010-11-15T11:10:14Z					biological_process											owl:Class	
GO:1905492	biolink:NamedThing	positive regulation of branching morphogenesis of a nerve	Any process that activates or increases the frequency, rate or extent of branching morphogenesis of a nerve.	tmpzr1t_l9r_go_relaxed.owl	upregulation of branching morphogenesis of a nerve|up-regulation of branching morphogenesis of a nerve|up regulation of branching morphogenesis of a nerve|activation of branching morphogenesis of a nerve							hbye	2016-09-23T14:11:52Z					biological_process											owl:Class	
GO:0042054	biolink:NamedThing	histone methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + histone = S-adenosyl-L-homocysteine + methyl-histone. Histone methylation generally occurs on either an arginine or lysine residue.	tmpzr1t_l9r_go_relaxed.owl	histone methylase activity				EC:2.1.1.354									molecular_function											owl:Class	
GO:0032927	biolink:NamedThing	positive regulation of activin receptor signaling pathway	Any process that activates or increases the frequency, rate or extent of the activity of any activin receptor signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of activin receptor signaling pathway|up regulation of activin receptor signaling pathway|stimulation of activin receptor signaling pathway|positive regulation of activin receptor signalling pathway|positive regulation of activin signaling pathway|upregulation of activin receptor signaling pathway|activation of activin receptor signaling pathway|positive regulation of activin signalling pathway													biological_process											owl:Class	
GO:0016701	biolink:NamedThing	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen	Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from one donor, and molecular oxygen is incorporated into a donor.	tmpzr1t_l9r_go_relaxed.owl	oxygenase|oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, miscellaneous				EC:1.13.-.-									molecular_function											owl:Class	
GO:1903366	biolink:NamedThing	negative regulation of fear response	Any process that stops, prevents or reduces the frequency, rate or extent of fear response.	tmpzr1t_l9r_go_relaxed.owl	down regulation of physiological fear response|down-regulation of physiological fear response|down-regulation of fear response|down regulation of fear response|downregulation of physiological fear response|inhibition of physiological fear response|downregulation of fear response|inhibition of fear response|negative regulation of physiological fear response							mr	2014-08-21T23:21:45Z					biological_process											owl:Class	
GO:0097623	biolink:NamedThing	potassium ion export across plasma membrane	The directed movement of potassium ions from inside of a cell, across the plasma membrane and into the extracellular region.	tmpzr1t_l9r_go_relaxed.owl	potassium export|potassium export across plasma membrane|potassium ion export|potassium ion export from cell	https://github.com/geneontology/go-ontology/issues/14265						pr	2009-12-16T11:10:45Z			GO:0098668|GO:0071435		biological_process											owl:Class	
GO:0050054	biolink:NamedThing	lignostilbene alpha beta-dioxygenase activity	Catalysis of the reaction: 1,2-bis(4-hydroxy-3-methoxyphenyl)ethylene + O(2) = 2 vanillin.	tmpzr1t_l9r_go_relaxed.owl	1,2-bis(4-hydroxy-3-methoxyphenyl)ethylene:oxygen oxidoreductase (alphabeta-bond-cleaving)|lignostilbene ab-dioxygenase activity|lignostilbene alphabeta-dioxygenase activity				MetaCyc:LIGNOSTILBENE-ALPHA-BETA-DIOXYGENASE-RXN|KEGG_REACTION:R00043|EC:1.13.11.43|RHEA:21340									molecular_function											owl:Class	
GO:0060754	biolink:NamedThing	positive regulation of mast cell chemotaxis	Any process that increases the rate, frequency or extent of mast cell chemotaxis. Mast cell chemotaxis is the movement of a mast cell in response to an external stimulus.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-06-22T02:38:19Z					biological_process											owl:Class	
GO:0097477	biolink:NamedThing	lateral motor column neuron migration	The orderly movement of a lateral motor column neuron from one site to another. A lateral motor column neuron is a motor neuron that is generated only on limb levels and send axons into the limb mesenchyme.	tmpzr1t_l9r_go_relaxed.owl								pr	2013-04-23T13:05:32Z					biological_process											owl:Class	
GO:0097476	biolink:NamedThing	spinal cord motor neuron migration	The orderly movement of a spinal cord motor neuron from one site to another. A spinal cord motor neuron is a motor neuron that passes from the spinal cord toward or to a muscle and conducts an impulse that causes movement.	tmpzr1t_l9r_go_relaxed.owl								pr	2013-04-23T13:03:46Z					biological_process											owl:Class	
GO:0008453	biolink:NamedThing	alanine-glyoxylate transaminase activity	Catalysis of the reaction: L-alanine + glyoxylate = pyruvate + glycine.	tmpzr1t_l9r_go_relaxed.owl	alanine--glyoxylate aminotransferase activity|alanine-glyoxylic aminotransferase activity|L-alanine:glyoxylate aminotransferase activity|L-alanine-glycine transaminase activity|AGT activity|alanine-glyoxylate aminotransferase activity				MetaCyc:ALANINE--GLYOXYLATE-AMINOTRANSFERASE-RXN|Reactome:R-HSA-904864|RHEA:24248|EC:2.6.1.44|Reactome:R-HSA-389684									molecular_function											owl:Class	
GO:0070146	biolink:NamedThing	mitochondrial aspartyl-tRNA aminoacylation	The process of coupling aspartate to aspartyl-tRNA in a mitochondrion, catalyzed by aspartyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0006422	biolink:NamedThing	aspartyl-tRNA aminoacylation	The process of coupling aspartate to aspartyl-tRNA, catalyzed by aspartyl-tRNA synthetase. The aspartyl-tRNA synthetase is a  class-II synthetase. The activated amino acid is transferred to the 3'-OH group of an aspartic acid  accetping tRNA.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0106255	biolink:NamedThing	hydroperoxy icosatetraenoate isomerase activity	A hydroperoxy icosatetraenoate <=> a hydroxy epoxy icosatrienoate.	tmpzr1t_l9r_go_relaxed.owl					EC:5.4.4.7|RHEA:55560			hjd	2020-03-20T14:00:30Z					molecular_function											owl:Class	
GO:0019657	biolink:NamedThing	glycolytic fermentation to propionate	Glycolytic fermentation resulting in the catabolism of glucose to propionate, yielding energy in the form of ATP; an alternative to the acrylate pathway to produce propionate.	tmpzr1t_l9r_go_relaxed.owl	succinate-propionate fermentation				MetaCyc:P108-PWY									biological_process											owl:Class	
GO:0006105	biolink:NamedThing	succinate metabolic process	The chemical reactions and pathways involving succinate, also known as butanedioate or ethane dicarboxylate, the dianion of succinic acid. Succinate is an important intermediate in metabolism and a component of the TCA cycle.	tmpzr1t_l9r_go_relaxed.owl	succinate metabolism													biological_process											owl:Class	
GO:0000394	biolink:NamedThing	RNA splicing, via endonucleolytic cleavage and ligation	Splicing of RNA via recognition of the folded RNA structure that brings the 5' and 3' splice sites into proximity and cleavage of the RNA at both the 3' and 5' splice sites by an endonucleolytic mechanism, followed by ligation of the exons.	tmpzr1t_l9r_go_relaxed.owl	mRNA splicing					Note that while typically associated with tRNA splicing, this mechanism of splicing is known to be used for some non-tRNA substrates, e.g. HAC1 (YFL031W) in S. cerevisiae and an intron in the 23S rRNA of the Archaeal species Desulfurococcus mobilis.								biological_process											owl:Class	
GO:0008380	biolink:NamedThing	RNA splicing	The process of removing sections of the primary RNA transcript to remove sequences not present in the mature form of the RNA and joining the remaining sections to form the mature form of the RNA.	tmpzr1t_l9r_go_relaxed.owl	pre-mRNA splicing factor activity				Wikipedia:RNA_splicing							GO:0006395		biological_process											owl:Class	
GO:0035790	biolink:NamedThing	platelet-derived growth factor receptor-alpha signaling pathway	A series of molecular signals initiated by the binding of a ligand to an alpha-type platelet-derived growth factor receptor (PDGFalpha) on the surface of a signal-receiving cell, and ending with regulation of a downstream cellular process, e.g. transcription.	tmpzr1t_l9r_go_relaxed.owl	platelet-derived growth factor receptor-alpha signalling pathway|PDGFR-alpha signaling pathway|alphaPDGF receptor signaling pathway|PDGF receptor-alpha signaling pathway							bf	2011-04-06T10:55:16Z					biological_process											owl:Class	
GO:1900075	biolink:NamedThing	positive regulation of neuromuscular synaptic transmission	Any process that activates or increases the frequency, rate or extent of neuromuscular synaptic transmission.	tmpzr1t_l9r_go_relaxed.owl	activation of neuromuscular synaptic transmission|upregulation of neuromuscular synaptic transmission|up regulation of neuromuscular synaptic transmission|up-regulation of neuromuscular synaptic transmission							kmv	2012-01-26T10:14:22Z					biological_process											owl:Class	
GO:0071280	biolink:NamedThing	cellular response to copper ion	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a copper ion stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to copper							mah	2009-12-10T03:57:03Z					biological_process											owl:Class	
GO:0046688	biolink:NamedThing	response to copper ion	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a copper ion stimulus.	tmpzr1t_l9r_go_relaxed.owl	copper sensitivity/resistance|response to copper													biological_process											owl:Class	
GO:0070568	biolink:NamedThing	guanylyltransferase activity	Catalysis of the transfer of a guanylyl group to an acceptor.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-04-15T11:05:47Z					molecular_function											owl:Class	
GO:1900858	biolink:NamedThing	regulation of brevianamide F biosynthetic process	Any process that modulates the frequency, rate or extent of brevianamide F biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of brevianamide F formation|regulation of brevianamide F biosynthesis|regulation of brevianamide F anabolism|regulation of brevianamide F synthesis							di	2012-06-07T09:52:56Z					biological_process											owl:Class	
GO:1901376	biolink:NamedThing	organic heteropentacyclic compound metabolic process	The chemical reactions and pathways involving organic heteropentacyclic compound.	tmpzr1t_l9r_go_relaxed.owl	organic heteropentacyclic compound metabolism							bf	2012-09-28T12:50:41Z					biological_process											owl:Class	
GO:1904014	biolink:NamedThing	response to serotonin	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a serotonin stimulus.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-03-06T19:33:54Z					biological_process											owl:Class	
GO:0071867	biolink:NamedThing	response to monoamine	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monoamine stimulus. A monoamine is any of a group of molecular messengers that contain one amino group that is connected to an aromatic ring by ethylene group (-CH2-CH2-). Monoamines are derived from the aromatic amino acids phenylalanine, tyrosine, histidine and tryptophan.	tmpzr1t_l9r_go_relaxed.owl	response to monoamine stimulus							mah	2010-09-13T02:36:37Z					biological_process											owl:Class	
GO:0004508	biolink:NamedThing	steroid 17-alpha-monooxygenase activity	Catalysis of the reaction: a steroid + AH2 + O2 = a 17a-hydroxysteroid + A + H2O.	tmpzr1t_l9r_go_relaxed.owl	cytochrome P45017alpha|steroid 17alpha-monooxygenase activity|steroid 17alphahydroxylase/17,20 lyase activity|steroid 17-alpha-hydroxylase activity|steroid 17alpha-hydroxylase activity|steroid 17-alpha-hydroxylase-C17-20 lyase activity|cytochrome p450 XVIIA1 activity|steroid 17-alpha-hydroxylase/17,20 lyase activity|steroid,hydrogen-donor:oxygen oxidoreductase (17alpha-hydroxylating)|cytochrome P450 CYP17|cytochrome P-450 (P-45017alpha,lyase)|17alpha-hydroxylase-C17,20 lyase activity				Reactome:R-HSA-193099|Reactome:R-HSA-193072|Reactome:R-HSA-5601843|EC:1.14.14.19|Reactome:R-HSA-9035954|Reactome:R-HSA-9035956|MetaCyc:STEROID-17-ALPHA-MONOOXYGENASE-RXN|Reactome:R-HSA-193068|Reactome:R-HSA-193070									molecular_function											owl:Class	
GO:0061963	biolink:NamedThing	regulation of entry into reproductive diapause	Any process that modulates the rate or extent of the dormancy process that results in entry into reproductive diapause. Reproductive diapause is a form of diapause where the organism itself will remain fully active, including feeding and other routine activities, but the reproductive organs experience a tissue-specific reduction in metabolism, with characteristic triggering and releasing stimuli.	tmpzr1t_l9r_go_relaxed.owl								dph	2018-02-05T15:02:16Z					biological_process											owl:Class	
GO:0010786	biolink:NamedThing	clathrin coating of Golgi vesicle, trans-Golgi to endosome targeting	The addition of clathrin and adaptor proteins to Golgi membranes during the formation of transport vesicles that will move from the trans-Golgi to the endosome, forming a vesicle coat.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0004135	biolink:NamedThing	amylo-alpha-1,6-glucosidase activity	Catalysis of the hydrolysis of (1->6)-alpha-D-glucosidic branch linkages in glycogen phosphorylase limit dextrin. Limit dextrin is the highly branched core that remains after exhaustive treatment of glycogen with glycogen phosphorylase. It is formed because these enzymes cannot hydrolyze the (1->6) glycosidic linkages present.	tmpzr1t_l9r_go_relaxed.owl	amylopectin 1,6-glucosidase activity|dextrin 6-alpha-D-glucosidase activity|dextrin-1,6-glucosidase activity|glycogen phosphorylase-limit dextrin alpha-1,6-glucohydrolase activity|amylo-1,6-glucosidase activity				Reactome:R-HSA-71593|EC:3.2.1.33|MetaCyc:3.2.1.33-RXN									molecular_function											owl:Class	
GO:2000719	biolink:NamedThing	negative regulation of maintenance of mitotic sister chromatid cohesion, centromeric	Any process that stops, prevents or reduces the frequency, rate or extent of maintenance of mitotic sister chromatid cohesion in the centromeric region.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of maintenance of centromeric mitotic sister chromatin cohesion|negative regulation of maintenance of mitotic sister chromatin cohesion at centromere|negative regulation of maintenance of sister chromatin cohesion at centromere at mitosis							mah	2011-06-03T10:41:14Z					biological_process											owl:Class	
GO:0034183	biolink:NamedThing	negative regulation of maintenance of mitotic sister chromatid cohesion	Any process that decreases the extent to which the association between sister chromatids of a replicated chromosome is maintained during a mitotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1903598	biolink:NamedThing	positive regulation of gap junction assembly	Any process that activates or increases the frequency, rate or extent of gap junction assembly.	tmpzr1t_l9r_go_relaxed.owl	up regulation of gap junction assembly|up-regulation of gap junction assembly|activation of gap junction assembly|upregulation of gap junction assembly							rl	2014-11-07T18:51:53Z					biological_process											owl:Class	
GO:0016999	biolink:NamedThing	antibiotic metabolic process	The chemical reactions and pathways involving an antibiotic, a substance produced by or derived from certain fungi, bacteria, and other organisms, that can destroy or inhibit the growth of other microorganisms.	tmpzr1t_l9r_go_relaxed.owl	antibiotic metabolism													biological_process											owl:Class	
GO:1905581	biolink:NamedThing	positive regulation of low-density lipoprotein particle clearance	Any process that activates or increases the frequency, rate or extent of low-density lipoprotein particle clearance.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of low-density lipoprotein particle clearance|upregulation of low-density lipoprotein particle clearance|up-regulation of LDL clearance|up regulation of low-density lipoprotein particle clearance|up regulation of LDL clearance|positive regulation of LDL clearance|upregulation of LDL clearance|activation of LDL clearance|activation of low-density lipoprotein particle clearance							nc	2016-10-19T14:39:15Z					biological_process											owl:Class	
GO:0010986	biolink:NamedThing	positive regulation of lipoprotein particle clearance	Any process that increases the rate, frequency, or extent of lipoprotein particle clearance. Lipoprotein particle clearance is the process in which a lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-06-01T12:08:19Z					biological_process											owl:Class	
GO:0019105	biolink:NamedThing	N-palmitoyltransferase activity	Catalysis of the transfer of a palmitoyl group to a nitrogen atom on the acceptor molecule.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0033106	biolink:NamedThing	cis-Golgi network membrane	The lipid bilayer surrounding any of the compartments that make up the cis-Golgi network.	tmpzr1t_l9r_go_relaxed.owl	cis Golgi network membrane|Golgi cis face membrane													cellular_component											owl:Class	
GO:2000155	biolink:NamedThing	positive regulation of cilium-dependent cell motility	Any process that activates or increases the frequency, rate or extent of cilium-dependent cell motility.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of ciliary cell motility							mah	2010-10-04T12:41:05Z					biological_process											owl:Class	
GO:2000147	biolink:NamedThing	positive regulation of cell motility	Any process that activates or increases the frequency, rate or extent of cell motility.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of cell movement|positive regulation of cell locomotion|positive regulation of movement of a cell							mah	2010-10-01T09:41:30Z					biological_process											owl:Class	
GO:0047930	biolink:NamedThing	glucosaminate ammonia-lyase activity	Catalysis of the reaction: D-glucosaminate = 2-dehydro-3-deoxy-D-gluconate + NH3.	tmpzr1t_l9r_go_relaxed.owl	acetylenemonocarboxylic acid hydrase activity|D-glucosaminate ammonia-lyase (isomerizing; 2-dehydro-3-deoxy-D-gluconate-forming)|D-glucosaminate ammonia-lyase activity|2-amino-2-deoxy-D-gluconate hydro-lyase (deaminating) activity|2-amino-2-deoxy-D-gluconate ammonia-lyase activity|glucosaminic dehydrase activity|D-glucosaminate dehydratase activity|aminodeoxygluconate ammonia-lyase activity|D-glucosaminic acid dehydrase activity|aminodeoxygluconate dehydratase activity				MetaCyc:4.3.1.21-RXN|EC:4.3.1.9|RHEA:12488	Note that this function was EC:4.3.1.21.						GO:0050443		molecular_function											owl:Class	
GO:0046014	biolink:NamedThing	negative regulation of T cell homeostatic proliferation	Any process that stops, prevents or reduces the rate or extent of resting T cell proliferation.	tmpzr1t_l9r_go_relaxed.owl	down regulation of T cell homeostatic proliferation|downregulation of T cell homeostatic proliferation|negative regulation of resting T cell proliferation|negative regulation of T lymphocyte homeostatic proliferation|negative regulation of T-lymphocyte homeostatic proliferation|down-regulation of T cell homeostatic proliferation|inhibition of T cell homeostatic proliferation|negative regulation of T-cell homeostatic proliferation													biological_process											owl:Class	
GO:0017053	biolink:NamedThing	transcription repressor complex	A protein complex that possesses activity that prevents or downregulates transcription.	tmpzr1t_l9r_go_relaxed.owl	transcription factor inhibitor complex|nuclear transcriptional repressor complex|cytoplasmic transcriptional repressor complex|transcriptional repressor complex							tb	2014-05-09T13:23:51Z			GO:0090569|GO:0090568		cellular_component											owl:Class	
GO:0005353	biolink:NamedThing	fructose transmembrane transporter activity	Enables the transfer of fructose from one side of a membrane to the other. Fructose exists in a open chain form or as a ring compound. D-fructose is the sweetest of the sugars and is found free in a large number of fruits and honey.	tmpzr1t_l9r_go_relaxed.owl	fructose permease activity|fructose porter activity				Reactome:R-HSA-189222							GO:0015585|GO:0019192		molecular_function											owl:Class	
GO:0044111	biolink:NamedThing	formation of structure involved in a symbiotic process	The progression of an organism from an initial condition to a later condition, occurring when the organism is in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	development involved in symbiotic interaction|development on or near surface of other organism involved in symbiotic interaction|development of symbiont involved in interaction with host|development during symbiotic interaction|development on or near surface of other organism during symbiotic interaction|development of symbiont during interaction with host	https://github.com/geneontology/go-ontology/issues/20305						jl	2009-07-30T02:26:46Z			GO:0044152|GO:0044115		biological_process											owl:Class	
GO:0046872	biolink:NamedThing	metal ion binding	Binding to a metal ion.	tmpzr1t_l9r_go_relaxed.owl	heavy metal binding|metal binding													molecular_function											owl:Class	
GO:1904610	biolink:NamedThing	response to 3,3',4,4',5-pentachlorobiphenyl	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 3,3',4,4',5-pentachlorobiphenyl stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to PCB 126							sl	2015-08-27T18:52:49Z					biological_process											owl:Class	
GO:0006550	biolink:NamedThing	isoleucine catabolic process	The chemical reactions and pathways resulting in the breakdown of isoleucine, (2R*,3R*)-2-amino-3-methylpentanoic acid.	tmpzr1t_l9r_go_relaxed.owl	isoleucine breakdown|isoleucine degradation|isoleucine catabolism				MetaCyc:ILEUDEG-PWY									biological_process											owl:Class	
GO:0006549	biolink:NamedThing	isoleucine metabolic process	The chemical reactions and pathways involving isoleucine, (2R*,3R*)-2-amino-3-methylpentanoic acid.	tmpzr1t_l9r_go_relaxed.owl	isoleucine metabolism													biological_process											owl:Class	
GO:0046476	biolink:NamedThing	glycosylceramide biosynthetic process	The chemical reactions and pathways resulting in the formation of glycosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of a monosaccharide (or derivative) by a ceramide group.	tmpzr1t_l9r_go_relaxed.owl	glycosylceramide synthesis|glycosylceramide formation|glycosylceramide biosynthesis|glycosylceramide anabolism													biological_process											owl:Class	
GO:1902553	biolink:NamedThing	positive regulation of catalase activity	Any process that activates or increases the frequency, rate or extent of catalase activity.	tmpzr1t_l9r_go_relaxed.owl	up regulation of catalase-peroxidase activity|activation of optidase activity|activation of haem catalase activity|up regulation of catalase reaction|up regulation of caperase activity|activation of catalase reaction|up-regulation of heme catalase activity|upregulation of optidase activity|positive regulation of hydrogen-peroxide:hydrogen-peroxide oxidoreductase activity|upregulation of catalase reaction|positive regulation of caperase activity|up-regulation of optidase activity|up-regulation of hydrogen-peroxide:hydrogen-peroxide oxidoreductase activity|activation of manganese catalase activity|upregulation of haem catalase activity|positive regulation of heme catalase activity|up regulation of optidase activity|activation of heme catalase activity|activation of CAT|activation of caperase activity|up-regulation of equilase activity|up-regulation of manganese catalase activity|positive regulation of catalase-peroxidase activity|up regulation of haem catalase activity|up regulation of heme catalase activity|activation of equilase activity|up regulation of manganese catalase activity|activation of catalase activity|upregulation of heme catalase activity|upregulation of catalase activity|up-regulation of CAT|upregulation of CAT|up regulation of equilase activity|up regulation of CAT|positive regulation of catalase reaction|positive regulation of optidase activity|upregulation of catalase-peroxidase activity|activation of hydrogen-peroxide:hydrogen-peroxide oxidoreductase activity|up-regulation of catalase activity|positive regulation of equilase activity|upregulation of manganese catalase activity|up-regulation of catalase-peroxidase activity|upregulation of equilase activity|up-regulation of catalase reaction|activation of catalase-peroxidase activity|up-regulation of bacterial catalase-peroxidase activity|up-regulation of haem catalase activity|activation of bacterial catalase-peroxidase activity|positive regulation of manganese catalase activity|up regulation of catalase activity|upregulation of bacterial catalase-peroxidase activity|up regulation of bacterial catalase-peroxidase activity|positive regulation of CAT|positive regulation of haem catalase activity|up regulation of hydrogen-peroxide:hydrogen-peroxide oxidoreductase activity|up-regulation of caperase activity|positive regulation of bacterial catalase-peroxidase activity|upregulation of caperase activity|upregulation of hydrogen-peroxide:hydrogen-peroxide oxidoreductase activity							tb	2013-12-04T21:56:03Z					biological_process											owl:Class	
GO:1902551	biolink:NamedThing	regulation of catalase activity	Any process that modulates the frequency, rate or extent of catalase activity.	tmpzr1t_l9r_go_relaxed.owl	regulation of CAT|regulation of equilase activity|regulation of heme catalase activity|regulation of haem catalase activity|regulation of optidase activity|regulation of caperase activity|regulation of catalase-peroxidase activity|regulation of manganese catalase activity|regulation of hydrogen-peroxide:hydrogen-peroxide oxidoreductase activity|regulation of catalase reaction|regulation of bacterial catalase-peroxidase activity							tb	2013-12-04T21:55:46Z					biological_process											owl:Class	
GO:0061633	biolink:NamedThing	transport-coupled glycolytic process through glucose-6-phosphate	The chemical reactions and pathways resulting in the breakdown of glucose into pyruvate, in which the glucose is converted to glucose-6-phosphate intermediate coupled to transmembrane transport.	tmpzr1t_l9r_go_relaxed.owl								dph	2014-06-19T09:12:37Z					biological_process											owl:Class	
GO:1901756	biolink:NamedThing	butirosin metabolic process	The chemical reactions and pathways involving butirosin.	tmpzr1t_l9r_go_relaxed.owl	butirosin metabolism							yaf	2013-01-14T11:36:18Z					biological_process											owl:Class	
GO:0034298	biolink:NamedThing	arthrospore formation	The formation of conidia by the conversion of a pre-existing hypha. An arthrospore is produced by the last cell on a hypha breaking off and dispersing. Usually the walls thicken and the cell(s) separates before swelling of each spore. Sometimes further septa form in each cell prior to disarticulation.	tmpzr1t_l9r_go_relaxed.owl	arthroconidium formation													biological_process											owl:Class	
GO:0046961	biolink:NamedThing	proton-transporting ATPase activity, rotational mechanism	Enables the transfer of protons from one side of a membrane to the other according to the reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out), by a rotational mechanism.	tmpzr1t_l9r_go_relaxed.owl	hydrogen ion translocating F-type ATPase activity|ATP synthase activity|F(1)-ATPase activity|hydrogen ion translocating V-type ATPase activity|ATP phosphohydrolase (H+-transporting) activity|hydrogen ion transporting two-sector ATPase activity|F0F1-ATPase|FoF1-ATPase|hydrogen ion translocating A-type ATPase activity|F(o)F(1)-ATPase activity|F1-ATPase|F(0)F(1)-ATPase activity|hydrogen ion transporting ATPase activity, rotational mechanism|H+-transporting ATPase activity|chloroplast ATPase activity|H(+)-transporting ATP synthase activity|mitochondrial ATPase activity				RHEA:57721									molecular_function											owl:Class	
GO:0044769	biolink:NamedThing	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism	Enables the transfer of ions from one side of a membrane to the other according to the reaction: ATP + H2O + ion(in) = ADP + phosphate + ion(out), by a rotational mechanism.	tmpzr1t_l9r_go_relaxed.owl								jl	2013-02-20T13:41:38Z					molecular_function											owl:Class	
GO:0060401	biolink:NamedThing	cytosolic calcium ion transport	The directed movement of calcium ions (Ca2+) into, out of or within the cytosol.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0006480	biolink:NamedThing	N-terminal protein amino acid methylation	The methylation of the N-terminal amino acid of a protein.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0005228	biolink:NamedThing	intracellular sodium activated potassium channel activity	Enables the transmembrane transfer of potassium by a channel that opens in response to stimulus by a sodium ion or ions. Transport by a channel involves facilitated diffusion of a solute (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel, without evidence for a carrier-mediated mechanism. Sodium activated potassium channels have distinctive properties, including a large single channel conductance, subconductance states, and a block of single channel currents at positive potentials, similar to inward rectification.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0035925	biolink:NamedThing	mRNA 3'-UTR AU-rich region binding	Binding to a region containing frequent adenine and uridine bases within the 3' untranslated region of a mRNA molecule or in pre-mRNA intron. The ARE-binding element consensus is UUAUUUAUU. ARE-binding proteins control the stability and/or translation of mRNAs.	tmpzr1t_l9r_go_relaxed.owl	ARE binding|mRNA 3'-UTR adenylate/uridylate-rich element binding|AU-rich element binding|adenylate/uridylate-rich element binding	https://github.com/geneontology/go-ontology/issues/16842						bf	2011-07-19T09:30:18Z			GO:0017091		molecular_function											owl:Class	
GO:1901022	biolink:NamedThing	4-hydroxyphenylacetate metabolic process	The chemical reactions and pathways involving 4-hydroxyphenylacetate.	tmpzr1t_l9r_go_relaxed.owl	4-hydroxyphenylacetate metabolism							yaf	2012-06-18T02:31:37Z					biological_process											owl:Class	
GO:0090515	biolink:NamedThing	L-glutamate transmembrane import into vacuole	The directed movement of L-glutamate into the vacuole across the vacuolar membrane.	tmpzr1t_l9r_go_relaxed.owl								tb	2012-12-14T11:25:52Z					biological_process											owl:Class	
GO:0015813	biolink:NamedThing	L-glutamate transmembrane transport	The directed movement of L-glutamate across a membrane.	tmpzr1t_l9r_go_relaxed.owl	mitochondrial aspartate/glutamate transport|L-glutamate transport											GO:0089711		biological_process											owl:Class	
GO:0044721	biolink:NamedThing	protein import into peroxisome matrix, substrate release	The process by which the cargo protein is released into the peroxisomal matrix, following translocation across the membrane.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-10-18T14:07:40Z					biological_process											owl:Class	
GO:0106057	biolink:NamedThing	negative regulation of calcineurin-mediated signaling	Any process that stops, prevents or reduces the frequency, rate or extent of calcineurin-mediated signalling.	tmpzr1t_l9r_go_relaxed.owl								hjd	2017-09-18T16:50:11Z					biological_process											owl:Class	
GO:0030960	biolink:NamedThing	peptide cross-linking via 3'-(O4'-L-tyrosinyl)-L-tyrosine	The modification of two peptidyl-tyrosines to form a 3'-(O4'-L-tyrosinyl)-L-tyrosine protein cross-link.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0368									biological_process											owl:Class	
GO:0044871	biolink:NamedThing	negative regulation by host of viral glycoprotein metabolic process	A process in which a host organism stops, prevents or reduces the frequency, rate or extent of viral glycoprotein metabolic process.	tmpzr1t_l9r_go_relaxed.owl								jl	2014-09-18T14:28:48Z					biological_process											owl:Class	
GO:0035155	biolink:NamedThing	negative regulation of terminal cell fate specification, open tracheal system	Any process that restricts, stops or prevents a cell from adopting a terminal cell fate in an open tracheal system. Once the terminal and fusion fates have been correctly induced, inhibitory feedback loops prevent the remaining branch cells from assuming similar fates.	tmpzr1t_l9r_go_relaxed.owl	down regulation of terminal cell fate specification|down-regulation of terminal cell fate specification|inhibition of terminal cell fate specification|downregulation of terminal cell fate specification|negative regulation of terminal cell fate specification													biological_process											owl:Class	
GO:0060016	biolink:NamedThing	granulosa cell development	The process whose specific outcome is the progression of a granulosa cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a granulosa cell fate.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0047475	biolink:NamedThing	phenylacetate-CoA ligase activity	Catalysis of the reaction: ATP + CoA + phenylacetate = AMP + diphosphate + H(+) + phenylacetyl-CoA.	tmpzr1t_l9r_go_relaxed.owl	PA-CoA ligase activity|phenacyl coenzyme A synthetase activity|phenylacetyl-CoA ligase activity|phenylacetyl-CoA ligase (AMP-forming)|phenylacetate:CoA ligase (AMP-forming)				EC:6.2.1.30|KEGG_REACTION:R02539|MetaCyc:PHENYLACETATE--COA-LIGASE-RXN|RHEA:20956									molecular_function											owl:Class	
GO:1900817	biolink:NamedThing	ochratoxin A catabolic process	The chemical reactions and pathways resulting in the breakdown of ochratoxin A.	tmpzr1t_l9r_go_relaxed.owl	ochratoxin A degradation|ochratoxin A breakdown|ochratoxin A catabolism							di	2012-06-04T10:13:26Z					biological_process											owl:Class	
GO:1901569	biolink:NamedThing	fatty acid derivative catabolic process	The chemical reactions and pathways resulting in the breakdown of fatty acid derivative.	tmpzr1t_l9r_go_relaxed.owl	fatty acid derivative breakdown|fatty acid derivative degradation|fatty acid derivative catabolism							pr	2012-11-04T17:13:40Z					biological_process											owl:Class	
GO:0021600	biolink:NamedThing	abducens nerve structural organization	The process that contributes to the act of creating the structural organization of the abducens nerve. This process pertains to the physical shaping of a rudimentary structure. The motor function of the abducens nerve is to contract the lateral rectus which results in abduction of the eye.	tmpzr1t_l9r_go_relaxed.owl	abducens nerve structural organisation|CN VI structural organization													biological_process											owl:Class	
GO:0002210	biolink:NamedThing	behavioral response to wounding	A behavioral response resulting from wounding.	tmpzr1t_l9r_go_relaxed.owl	behavioural response to wounding													biological_process											owl:Class	
GO:0018007	biolink:NamedThing	N-terminal peptidyl-glycine N-glucuronylation	The glucuronylation of the N-terminal glycine of proteins to form the derivative D-glucuronyl-N-glycine.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0058									biological_process											owl:Class	
GO:0018006	biolink:NamedThing	N-terminal protein amino acid glucuronylation	The glucuronylation of the N-terminal amino acid of proteins.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0050214	biolink:NamedThing	progesterone monooxygenase activity	Catalysis of the reaction: AH(2) + O(2) + progesterone = A + H(2)O + testosterone acetate.	tmpzr1t_l9r_go_relaxed.owl	progesterone,hydrogen-donor:oxygen oxidoreductase (hydroxylating)|progesterone hydroxylase activity				KEGG_REACTION:R02212|RHEA:11984|MetaCyc:PROGESTERONE-MONOOXYGENASE-RXN|EC:1.14.99.4									molecular_function											owl:Class	
GO:0046658	biolink:NamedThing	anchored component of plasma membrane	The component of the plasma membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group, that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping.	tmpzr1t_l9r_go_relaxed.owl	anchored to plasma membrane|plasma membrane, GPI-anchored													cellular_component											owl:Class	
GO:0031226	biolink:NamedThing	intrinsic component of plasma membrane	The component of the plasma membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.	tmpzr1t_l9r_go_relaxed.owl	intrinsic to plasma membrane													cellular_component											owl:Class	
GO:0042186	biolink:NamedThing	o-xylene catabolic process	The chemical reactions and pathways resulting in the breakdown of o-xylene, (1,2-dimethylbenzene) a colorless, liquid aromatic hydrocarbon.	tmpzr1t_l9r_go_relaxed.owl	ortho-xylene catabolism|o-xylene degradation|o-xylene catabolism|o-xylene breakdown|ortho-xylene catabolic process													biological_process											owl:Class	
GO:0018950	biolink:NamedThing	o-xylene metabolic process	The chemical reactions and pathways involving o-xylene, (1,2-dimethylbenzene) a colorless, liquid aromatic hydrocarbon.	tmpzr1t_l9r_go_relaxed.owl	ortho-xylene metabolism|ortho-xylene metabolic process|o-xylene metabolism				UM-BBD_pathwayID:oxy									biological_process											owl:Class	
GO:0019401	biolink:NamedThing	alditol biosynthetic process	The chemical reactions and pathways resulting in the formation of alditols, any polyhydric alcohol derived from the acyclic form of a monosaccharide by reduction of its aldehyde or keto group to an alcoholic group.	tmpzr1t_l9r_go_relaxed.owl	alditol formation|alditol anabolism|alditol biosynthesis|alditol synthesis													biological_process											owl:Class	
GO:0006000	biolink:NamedThing	fructose metabolic process	The chemical reactions and pathways involving fructose, the ketohexose arabino-2-hexulose. Fructose exists in a open chain form or as a ring compound. D-fructose is the sweetest of the sugars and is found free in a large number of fruits and honey.	tmpzr1t_l9r_go_relaxed.owl	fructose metabolism				Wikipedia:Fructose									biological_process											owl:Class	
GO:0047276	biolink:NamedThing	N-acetyllactosaminide 3-alpha-galactosyltransferase activity	Catalysis of the reaction: beta-D-galactosyl-(1,4)-beta-N-acetyl-D-glucosaminyl-R + UDP-galactose = alpha-D-galactosyl-(1,3)-beta-D-galactosyl-(1,4)-beta-N-acetyl-D-glucosaminyl-R + UDP.	tmpzr1t_l9r_go_relaxed.owl	UDP-Gal:N-acetyllactosaminide alpha-1,3-D-galactosyltransferase activity|UDP-galactose-acetyllactosamine alpha-D-galactosyltransferase activity|alpha-galactosyltransferase activity|UDP-Gal:Gal-beta-1->4GlcNAc-R alpha-1->3-galactosyltransferase activity|uridine diphosphogalactose-acetyllactosamine alpha-1->3-galactosyltransferase activity|N-acetyllactosaminide alpha-1,3-galactosyltransferase activity|UDP-Gal:N-acetyllactosaminide alpha(1,3)-galactosyltransferase activity|UDP-Gal:Galbeta1->4GlcNAc-R alpha1->3-galactosyltransferase activity|beta-galactosyl-N-acetylglucosaminylglycopeptide alpha-1,3-galactosyltransferase activity|uridine diphosphogalactose-galactosylacetylglucosaminylgalactosyl-glucosylceramide galactosyltransferase activity|UDP-Gal:N-acetyllactosaminide alpha-(1,3)-galactosyltransferase activity|glucosaminylglycopeptide alpha-1,3-galactosyltransferase activity|uridine diphosphogalactose-acetyllactosamine alpha1->3-galactosyltransferase activity|UDPgalactose:beta-D-galactosyl-beta-1,4-N-acetyl-D-glucosaminyl-glycopeptide alpha-1,3-D-galactosyltransferase activity|uridine diphosphogalactose-acetyllactosamine galactosyltransferase activity|UDP-Gal:beta-D-Gal(1,4)-D-GlcNAc alpha-(1,3)-galactosyltransferase activity|uridine diphosphogalactose-galactosylacetylglucosaminylgalactosylglucosylceramide galactosyltransferase activity|UDP-galactose:N-acetyllactosaminide 3-alpha-D-galactosyltransferase activity|beta-D-galactosyl-N-acetylglucosaminylglycopeptide alpha-1,3-galactosyltransferase activity|UDP-Gal:beta-D-Gal(1,4)-D-GlcNAc alpha(1,3)-galactosyltransferase activity				MetaCyc:2.4.1.151-RXN|RHEA:13013|EC:2.4.1.87							GO:0003946		molecular_function											owl:Class	
GO:1900428	biolink:NamedThing	regulation of filamentous growth of a population of unicellular organisms	Any process that modulates the frequency, rate or extent of filamentous growth of a population of unicellular organisms.	tmpzr1t_l9r_go_relaxed.owl								di	2012-04-25T05:53:33Z					biological_process											owl:Class	
GO:0038150	biolink:NamedThing	C-C chemokine receptor CCR2 signaling pathway	A series of molecular signals initiated by a the C-C chemokine type 2 receptor (CCR2) on the surface of a cell binding to one of it's physiological ligands, and ending with regulation of a downstream cellular process, e.g. transcription.	tmpzr1t_l9r_go_relaxed.owl	C-C chemokine receptor type 2 signaling pathway							bf	2012-05-11T11:41:02Z					biological_process											owl:Class	
GO:0019877	biolink:NamedThing	diaminopimelate biosynthetic process	The chemical reactions and pathways resulting in the formation of diaminopimelate, both as an intermediate in lysine biosynthesis and as a component (as meso-diaminopimelate) of the peptidoglycan of Gram-negative bacterial cell walls.	tmpzr1t_l9r_go_relaxed.owl	diaminopimelate synthesis|diaminopimelate biosynthesis|diaminopimelate anabolism|diaminopimelate formation													biological_process											owl:Class	
GO:0043650	biolink:NamedThing	dicarboxylic acid biosynthetic process	The chemical reactions and pathways resulting in the formation of dicarboxylic acids, any organic acid containing two carboxyl (-COOH) groups.	tmpzr1t_l9r_go_relaxed.owl	dicarboxylic acid anabolism|dicarboxylic acid formation|dicarboxylate biosynthesis|dicarboxylate biosynthetic process|dicarboxylic acid synthesis|dicarboxylic acid biosynthesis													biological_process											owl:Class	
GO:1905348	biolink:NamedThing	endonuclease complex	A protein complex which is capable of endonuclease activity.	tmpzr1t_l9r_go_relaxed.owl						An example of this is MUS81 in human (Q96NY9) in PMID:18413719 (inferred from direct assay).		bhm	2016-08-03T12:27:00Z					cellular_component											owl:Class	
GO:0043612	biolink:NamedThing	isoprene biosynthetic process	The chemical reactions and pathways resulting in the formation of isoprene, C5H8.	tmpzr1t_l9r_go_relaxed.owl	2-methyl-1,3-butadiene biosynthesis|hemiterpene biosynthetic process|2-methyl-1,3-butadiene biosynthetic process|hemiterpene biosynthesis													biological_process											owl:Class	
GO:0042653	biolink:NamedThing	mitochondrial respiratory chain complex I, membrane segment	The mitochondrial membrane segment of respiratory chain complex I. Respiratory chain complex I is an enzyme of the respiratory chain, consisting of at least 34 polypeptide chains. The electrons of NADH enter the chain at this complex. The complete complex is L-shaped, with a horizontal arm lying in the membrane and a vertical arm that projects into the matrix.	tmpzr1t_l9r_go_relaxed.owl	NADH-Q oxidoreductase complex, membrane segment													cellular_component											owl:Class	
GO:0033387	biolink:NamedThing	putrescine biosynthetic process from ornithine	The chemical reactions and pathways resulting in the formation of putrescine, 1,4-diaminobutane by decarboxylation of ornithine.	tmpzr1t_l9r_go_relaxed.owl	putrescine synthesis from ornithine|putrescine anabolism from ornithine|putrescine formation from ornithine|putrescine biosynthesis from ornithine													biological_process											owl:Class	
GO:1902122	biolink:NamedThing	chenodeoxycholic acid binding	Binding to chenodeoxycholic acid.	tmpzr1t_l9r_go_relaxed.owl	CDCA binding							bf	2013-05-16T09:17:19Z					molecular_function											owl:Class	
GO:0014064	biolink:NamedThing	positive regulation of serotonin secretion	Any process that activates or increases the frequency, rate or extent of the regulated release of serotonin.	tmpzr1t_l9r_go_relaxed.owl	stimulation of serotonin secretion|up-regulation of serotonin secretion|positive regulation of serotonin release|activation of serotonin secretion|up regulation of serotonin secretion|upregulation of serotonin secretion													biological_process											owl:Class	
GO:0099641	biolink:NamedThing	anterograde axonal protein transport	The directed movement of proteins along microtubules from the cell body toward the cell periphery in nerve cell axons.	tmpzr1t_l9r_go_relaxed.owl	anterograde axon cargo transport													biological_process											owl:Class	
GO:0103055	biolink:NamedThing	gibberelli A15, 2-oxoglutarate:oxygen oxidoreductase activity	Catalysis of the reaction: gibberellin A15 + 2-oxoglutarate + O2 <=> gibberellin A24 + succinate + carbon dioxide + H2O.	tmpzr1t_l9r_go_relaxed.owl					RHEA:60780|MetaCyc:RXN1F-163									molecular_function											owl:Class	
GO:0010804	biolink:NamedThing	negative regulation of tumor necrosis factor-mediated signaling pathway	Any process that decreases the rate or extent of the tumor necrosis factor-mediated signaling pathway. The tumor necrosis factor-mediated signaling pathway is the series of molecular signals generated as a consequence of tumor necrosis factor binding to a cell surface receptor.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of TNF signaling|negative regulation of tumor necrosis factor-mediated signalling pathway|negative regulation of TNF-mediated signaling pathway													biological_process											owl:Class	
GO:2000333	biolink:NamedThing	negative regulation of blood microparticle formation	Any process that stops, prevents or reduces the frequency, rate or extent of blood microparticle formation.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of microparticle release|negative regulation of microparticle generation							mah	2011-01-31T11:18:18Z					biological_process											owl:Class	
GO:0071629	biolink:NamedThing	cytoplasm protein quality control by the ubiquitin-proteasome system	The chemical reactions and pathways resulting in the breakdown of misfolded proteins in the cytoplasm, which are targeted to cytoplasmic proteasomes for degradation.	tmpzr1t_l9r_go_relaxed.owl	cytoplasm-associated proteasomal ubiquitin-dependent protein catabolism|ubiquitin-dependent catabolism of misfolded proteins by cytoplasm-associated proteasome|cytoplasm-associated proteasomal ubiquitin-dependent protein degradation|cytoplasm-associated proteasomal ubiquitin-dependent protein breakdown					See also the biological process terms 'unfolded protein response ; GO:0030968' and 'retrograde protein transport, ER to cytosol ; GO:0030970'.		mah	2010-02-11T03:06:57Z					biological_process											owl:Class	
GO:0001504	biolink:NamedThing	neurotransmitter uptake	The directed movement of neurotransmitters into neurons or glial cells. This process leads to inactivation and recycling of neurotransmitters.	tmpzr1t_l9r_go_relaxed.owl	neurotransmitter import into glial cell|neurotransmitter import|neurotransmitter recycling|neurotransmitter import into neuron													biological_process											owl:Class	
GO:0106109	biolink:NamedThing	positive regulation of (R)-mevalonic acid biosynthetic process	Any process that activates or increases the frequency, rate or extent of (R)-mevalonic acid biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl								hjd	2018-03-27T14:20:47Z					biological_process											owl:Class	
GO:0051035	biolink:NamedThing	DNA transmembrane transporter activity	Enables the transfer of DNA, deoxyribonucleic acid, from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0099559	biolink:NamedThing	maintenance of alignment of postsynaptic density and presynaptic active zone	The process by which alignment between postsynaptic density and presynaptic active zone is maintained.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0047970	biolink:NamedThing	guanidinoacetase activity	Catalysis of the reaction: guanidinoacetate + H(2)O = glycine + urea.	tmpzr1t_l9r_go_relaxed.owl	glycocyaminase activity|guanidinoacetate amidinohydrolase activity				KEGG_REACTION:R00775|RHEA:23268|EC:3.5.3.2|MetaCyc:GUANIDINOACETASE-RXN									molecular_function											owl:Class	
GO:0048719	biolink:NamedThing	epistomal sclerite morphogenesis	The process in which the anatomical structures of the epistomal sclerite are generated and organized.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0018783	biolink:NamedThing	deisopropyldeethylatrazine hydrolase activity	Catalysis of the reaction: deisopropyldeethylatrazine + H2O = 2-chloro-4-hydroxy-6-amino-1,3,5-triazine + NH3.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0016518	biolink:NamedThing	interleukin-14 receptor activity	Combining with interleukin-14 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	IL-14 receptor activity|IL-14R													molecular_function											owl:Class	
GO:0046028	biolink:NamedThing	electron transporter, transferring electrons from cytochrome b6/f complex of photosystem II activity	Enables the directed movement of electrons from the cytochrome b6/f complex of photosystem II.	tmpzr1t_l9r_go_relaxed.owl	plastocyanin													molecular_function											owl:Class	
GO:0051596	biolink:NamedThing	methylglyoxal catabolic process	The chemical reactions and pathways resulting in the breakdown of methylglyoxal, CH3-CO-CHO, the aldehyde of pyruvic acid.	tmpzr1t_l9r_go_relaxed.owl	methylglyoxal breakdown|methylglyoxal catabolism|methylglyoxal degradation				MetaCyc:METHGLYUT-PWY|MetaCyc:Methylglyoxal-Detoxification									biological_process											owl:Class	
GO:0009438	biolink:NamedThing	methylglyoxal metabolic process	The chemical reactions and pathways involving methylglyoxal, CH3-CO-CHO, the aldehyde of pyruvic acid.	tmpzr1t_l9r_go_relaxed.owl	methylglyoxal pathway|methylglyoxal metabolism|methylglyoxal bypass				MetaCyc:METHGLYUT-PWY									biological_process											owl:Class	
GO:0002129	biolink:NamedThing	wobble position guanine ribose methylation	The process in which the ribose of guanosine at position 34 in the anticodon of a tRNA is post-transcriptionally methylated at the 2'-O position.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0002938	biolink:NamedThing	tRNA guanine ribose methylation	The process whereby a guanosine residue in a tRNA is methylated on the 2'-hydroxyl group of the ribose moiety.	tmpzr1t_l9r_go_relaxed.owl								hjd	2012-11-02T15:55:55Z					biological_process											owl:Class	
GO:0060700	biolink:NamedThing	regulation of ribonuclease activity	Any process that modulates the rate, frequency, or extent of ribonuclease activity, catalysis of the hydrolysis of phosphodiester bonds in chains of RNA.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-06-08T02:45:46Z					biological_process											owl:Class	
GO:0071088	biolink:NamedThing	alpha5-beta1 integrin-tissue transglutaminase complex	A protein complex that consists of an alpha5-beta1 integrin complex bound to tissue transglutaminase.	tmpzr1t_l9r_go_relaxed.owl	ITGA5-ITGB1-TGM2 complex							mah	2009-11-06T04:45:47Z					cellular_component											owl:Class	
GO:0090034	biolink:NamedThing	regulation of chaperone-mediated protein complex assembly	Any process that modulates the frequency, rate, or extent of chaperone-mediated protein complex assembly. Chaperone-mediated protein complex assembly is the aggregation, arrangement and bonding together of a set of components to form a protein complex, mediated by chaperone molecules that do not form part of the finished complex.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-08-03T11:12:37Z					biological_process											owl:Class	
GO:0015190	biolink:NamedThing	L-leucine transmembrane transporter activity	Enables the transfer of L-leucine from one side of a membrane to the other. L-leucine is 2-amino-4-methylpentanoic acid.	tmpzr1t_l9r_go_relaxed.owl	L-leucine transporter activity|leucine/isoleucine/valine porter activity|leucine/valine/isoleucine permease activity													molecular_function											owl:Class	
GO:1904309	biolink:NamedThing	response to cordycepin	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cordycepin stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to 3'-deoxyadenosine							sl	2015-06-10T17:10:29Z					biological_process											owl:Class	
GO:0010262	biolink:NamedThing	somatic embryogenesis	Initiation of a somatic embryo-an embryo arising from previously differentiated somatic cells, rather than from fused haploid gametes.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0031099	biolink:NamedThing	regeneration	The regrowth of a lost or destroyed body part, such as an organ or tissue. This process may occur via renewal, repair, and/or growth alone (i.e. increase in size or mass).	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Regeneration_(biology)									biological_process											owl:Class	
GO:0015243	biolink:NamedThing	cycloheximide transmembrane transporter activity	Enables the transfer of cycloheximide from one side of a membrane to the other.  Cycloheximide is an antibiotic produced by Streptomyces which interferes with protein synthesis in eukaryotes.	tmpzr1t_l9r_go_relaxed.owl	cycloheximide transporter activity													molecular_function											owl:Class	
GO:1905239	biolink:NamedThing	regulation of canonical Wnt signaling pathway involved in osteoblast differentiation	Any process that modulates the frequency, rate or extent of canonical Wnt signaling pathway involved in osteoblast differentiation.	tmpzr1t_l9r_go_relaxed.owl	regulation of canonical Wnt-activated signaling pathway involved in osteoblast differentiation|regulation of canonical Wnt receptor signalling pathway involved in osteoblast differentiation|regulation of canonical Wnt receptor signaling pathway involved in osteoblast differentiation							rph	2016-06-08T10:26:33Z					biological_process											owl:Class	
GO:0019698	biolink:NamedThing	D-galacturonate catabolic process	The chemical reactions and pathways resulting in the breakdown of D-galacturonate, the D-enantiomer of galacturonate, the anion of galacturonic acid.	tmpzr1t_l9r_go_relaxed.owl	D-galacturonate breakdown|D-galacturonate degradation|D-galacturonate catabolism				MetaCyc:GALACTUROCAT-PWY									biological_process											owl:Class	
GO:0035015	biolink:NamedThing	elongation of arista core	The increase in length of the aristal core. The arista is the terminal segment of the antenna and consists of a central core and a series of lateral extensions.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0044282	biolink:NamedThing	small molecule catabolic process	The chemical reactions and pathways resulting in the breakdown of small molecules, any low molecular weight, monomeric, non-encoded molecule.	tmpzr1t_l9r_go_relaxed.owl	small molecule catabolism					Small molecules in GO include monosaccharides but exclude disaccharides and polysaccharides.		jl	2010-01-26T12:06:10Z					biological_process											owl:Class	
GO:0044281	biolink:NamedThing	small molecule metabolic process	The chemical reactions and pathways involving small molecules, any low molecular weight, monomeric, non-encoded molecule.	tmpzr1t_l9r_go_relaxed.owl	small molecule metabolism					Small molecules in GO include monosaccharides but exclude disaccharides and polysaccharides.		jl	2010-01-26T12:05:20Z					biological_process											owl:Class	
GO:0051688	biolink:NamedThing	maintenance of plastid location	Any process in which a plastid is maintained in a specific location within a cell and prevented from moving elsewhere.	tmpzr1t_l9r_go_relaxed.owl	maintenance of plastid localization													biological_process											owl:Class	
GO:0051657	biolink:NamedThing	maintenance of organelle location	Any process in which an organelle is maintained in a specific location within a cell and prevented from moving elsewhere.	tmpzr1t_l9r_go_relaxed.owl	maintenance of organelle localization													biological_process											owl:Class	
GO:1900916	biolink:NamedThing	positive regulation of octadecene biosynthetic process	Any process that activates or increases the frequency, rate or extent of octadecene biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	upregulation of octadecene anabolism|up-regulation of 1-octadecene biosynthetic process|upregulation of octadecene biosynthesis|positive regulation of octadecene anabolism|upregulation of octadecene formation|up-regulation of octadecene biosynthesis|up regulation of octadecene synthesis|up regulation of octadecene biosynthesis|activation of octadecene synthesis|activation of octadecene biosynthetic process|up-regulation of octadecene formation|up regulation of 1-octadecene biosynthetic process|positive regulation of 1-octadecene biosynthetic process|positive regulation of octadecene biosynthesis|positive regulation of octadecene formation|up regulation of octadecene anabolism|up-regulation of octadecene synthesis|up-regulation of octadecene anabolism|up regulation of octadecene biosynthetic process|upregulation of 1-octadecene biosynthetic process|up regulation of octadecene formation|activation of octadecene formation|activation of 1-octadecene biosynthetic process|positive regulation of octadecene synthesis|upregulation of octadecene synthesis|upregulation of octadecene biosynthetic process|up-regulation of octadecene biosynthetic process|activation of octadecene biosynthesis|activation of octadecene anabolism							tt	2012-06-13T04:24:55Z					biological_process											owl:Class	
GO:1900919	biolink:NamedThing	positive regulation of octadecene metabolic process	Any process that activates or increases the frequency, rate or extent of octadecene metabolic process.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of octadecene metabolic process|activation of octadecene metabolism|up regulation of octadecene metabolic process|up-regulation of octadecene metabolism|activation of octadecene metabolic process|positive regulation of octadecene metabolism|upregulation of octadecene metabolism|up regulation of octadecene metabolism|upregulation of octadecene metabolic process							tt	2012-06-13T04:26:42Z					biological_process											owl:Class	
GO:0047150	biolink:NamedThing	betaine-homocysteine S-methyltransferase activity	Catalysis of the reaction: L-homocysteine + betaine = N,N-dimethylglycine + L-methionine.	tmpzr1t_l9r_go_relaxed.owl	betaine-homocysteine methyltransferase activity|trimethylammonioacetate:L-homocysteine S-methyltransferase activity|betaine-homocysteine transmethylase activity				EC:2.1.1.5|MetaCyc:2.1.1.5-RXN|Reactome:R-HSA-1614654|KEGG_REACTION:R02821|RHEA:22336									molecular_function											owl:Class	
GO:0090187	biolink:NamedThing	positive regulation of pancreatic juice secretion	Any process that increases the rate, frequency or extent of pancreatic juice secretion, the regulated release of pancreatic juice by the exocrine pancreas into the upper part of the intestine.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-12-18T11:03:24Z					biological_process											owl:Class	
GO:0043143	biolink:NamedThing	regulation of translation by machinery localization	Any process in which proteins and protein complexes involved in translation are transported to, or maintained in, a specific location.	tmpzr1t_l9r_go_relaxed.owl	establishment and maintenance of translational protein localization|regulation of translation by machinery localisation|establishment and maintenance of translational machinery localization|translational protein localization|translational machinery localization													biological_process											owl:Class	
GO:1901540	biolink:NamedThing	ent-pimara-8(14),15-diene catabolic process	The chemical reactions and pathways resulting in the breakdown of ent-pimara-8(14),15-diene.	tmpzr1t_l9r_go_relaxed.owl	ent-pimara-8(14),15-diene catabolism|ent-pimara-8(14),15-diene degradation|ent-pimara-8(14),15-diene breakdown							di	2012-10-25T15:38:17Z					biological_process											owl:Class	
GO:1901539	biolink:NamedThing	ent-pimara-8(14),15-diene metabolic process	The chemical reactions and pathways involving ent-pimara-8(14),15-diene.	tmpzr1t_l9r_go_relaxed.owl	ent-pimara-8(14),15-diene metabolism							di	2012-10-25T15:38:13Z					biological_process											owl:Class	
GO:0090021	biolink:NamedThing	positive regulation of posterior neural plate formation by Wnt signaling pathway	The series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of the target cell and increasing the rate or extent of posterior neural plate formation.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of posterior neural plate formation by Wnt-activated signaling pathway|positive regulation of posterior neural plate formation by Wnt receptor signaling pathway|positive regulation of posterior neural plate formation by Wnt receptor signalling pathway							tb	2009-07-29T11:44:13Z					biological_process											owl:Class	
GO:0006756	biolink:NamedThing	AMP phosphorylation	The process of introducing a phosphate group into AMP, adenosine monophosphate, to produce ADP. Addition of two phosphate groups produces ATP.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0046033	biolink:NamedThing	AMP metabolic process	The chemical reactions and pathways involving AMP, adenosine monophosphate.	tmpzr1t_l9r_go_relaxed.owl	adenylate forming enzyme activity|AMP metabolism													biological_process											owl:Class	
GO:1990899	biolink:NamedThing	meiotic DNA double-strand break resectioning	The process following clipping in double-strand break processing of SPO11 induced breaks, where long-tract single-stranded 3'-end DNA is generated from naked (SPO11 has been removed) 5' ends.	tmpzr1t_l9r_go_relaxed.owl								al	2015-11-10T17:23:07Z					biological_process											owl:Class	
GO:0075202	biolink:NamedThing	regulation of penetration hypha formation	Any process that modulates the frequency, rate or extent of symbiont penetration hypha formation for entry into host. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	modulation of symbiont penetration hypha formation for entry into host	https://github.com/geneontology/go-ontology/issues/21121				Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products from the symbiont involved in this process.								biological_process											owl:Class	
GO:0052372	biolink:NamedThing	modulation by symbiont of entry into host	Any process in which an organism modulates the frequency, rate or extent to which it enters into the host organism, where the two organisms are in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	modulation by organism of entry into other organism during symbiotic interaction|regulation by organism of entry into other organism during symbiotic interaction|regulation by organism of entry into other organism involved in symbiotic interaction	https://github.com/geneontology/go-ontology/issues/19027										GO:0052371		biological_process											owl:Class	
GO:1905855	biolink:NamedThing	positive regulation of heparan sulfate binding	Any process that activates or increases the frequency, rate or extent of heparan sulfate binding.	tmpzr1t_l9r_go_relaxed.owl	up regulation of heparan sulfate binding|activation of heparan sulfate binding|upregulation of heparan sulfate binding|up-regulation of heparan sulfate binding							bc	2017-01-23T13:25:47Z					biological_process											owl:Class	
GO:1905853	biolink:NamedThing	regulation of heparan sulfate binding	Any process that modulates the frequency, rate or extent of heparan sulfate binding.	tmpzr1t_l9r_go_relaxed.owl								bc	2017-01-23T13:25:30Z					biological_process											owl:Class	
GO:0007134	biolink:NamedThing	meiotic telophase I	The cell cycle phase which follows anaphase I of meiosis and during which the chromosomes arrive at the poles of the cell and the division of the cytoplasm starts.	tmpzr1t_l9r_go_relaxed.owl						Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).								biological_process											owl:Class	
GO:0098764	biolink:NamedThing	meiosis I cell cycle phase	A meiotic cell cycle phase prior to a during which some part of meiosis I nuclear division or the proceeding cytokinesis occurs.	tmpzr1t_l9r_go_relaxed.owl						Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).								biological_process											owl:Class	
GO:0044579	biolink:NamedThing	butyryl-CoA biosynthetic process from acetyl-CoA	The chemical reactions and pathway resulting in the formation of butyryl-CoA, starting from acetyl-CoA.	tmpzr1t_l9r_go_relaxed.owl	butyryl-CoA biosynthesis from acetyl-CoA							jl	2012-04-19T04:25:07Z					biological_process											owl:Class	
GO:0048303	biolink:NamedThing	negative regulation of isotype switching to IgG isotypes	Any process that stops, prevents, or reduces the frequency, rate or extent of isotype switching to IgG isotypes.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of class switch recombination to IgG isotypes|negative regulation of class switching to IgG isotypes|downregulation of isotype switching to IgG isotypes|down-regulation of isotype switching to IgG isotypes|inhibition of isotype switching to IgG isotypes|negative regulation of isotype switch recombination to IgG isotypes|down regulation of isotype switching to IgG isotypes													biological_process											owl:Class	
GO:1902151	biolink:NamedThing	regulation of response to DNA integrity checkpoint signaling	Any process that modulates the frequency, rate or extent of response to DNA integrity checkpoint signaling.	tmpzr1t_l9r_go_relaxed.owl	regulation of DNA integrity checkpoint effector process|regulation of response to signal involved in DNA integrity checkpoint							jl	2013-05-21T15:44:26Z					biological_process											owl:Class	
GO:0062189	biolink:NamedThing	anandamide 14,15 epoxidase activity	Catalysis of the reaction: N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine + O2 + reduced [NADPH--hemoprotein reductase] = H(+) + H2O + N-(14,15-epoxy-5Z,8Z,11Z-eicosatrienoyl)-ethanolamine + oxidized [NADPH--hemoprotein reductase].	tmpzr1t_l9r_go_relaxed.owl					RHEA:53148			dph	2019-11-26T18:57:55Z					molecular_function											owl:Class	
GO:2000268	biolink:NamedThing	positive regulation of blood coagulation, intrinsic pathway	Any process that activates or increases the frequency, rate or extent of blood coagulation, intrinsic pathway.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-11-23T11:45:51Z					biological_process											owl:Class	
GO:0070987	biolink:NamedThing	error-free translesion synthesis	The conversion of DNA-damage induced single-stranded gaps into large molecular weight DNA after replication by using a specialized DNA polymerase or replication complex to insert a defined nucleotide across the lesion. This process does not remove the replication-blocking lesions but does not causes an increase in the endogenous mutation level. For S. cerevisiae, RAD30 encodes DNA polymerase eta, which incorporates two adenines. When incorporated across a thymine-thymine dimer, it does not increase the endogenous mutation level.	tmpzr1t_l9r_go_relaxed.owl						Note that 'error-free' does not mean that literally zero errors occur during DNA synthesis, but that the error rate is low, comparable to that of DNA synthesis during replication.		mah	2009-10-29T02:45:42Z					biological_process											owl:Class	
GO:0019985	biolink:NamedThing	translesion synthesis	The replication of damaged DNA by synthesis across a lesion in the template strand; a specialized DNA polymerase or replication complex inserts a defined nucleotide across from the lesion which allows DNA synthesis to continue beyond the lesion. This process can be mutagenic depending on the damaged nucleotide and the inserted nucleotide.	tmpzr1t_l9r_go_relaxed.owl	bypass DNA synthesis													biological_process											owl:Class	
GO:0034519	biolink:NamedThing	cytoplasmic RNA cap binding complex	A protein complex found in the cytoplasm that binds the 5' cap structure of an mRNA, and typically consists of the cap-binding protein eIF4E, the adaptor protein eIF4G, and a multi-factor complex comprising eIF1, eIF2, eIF3 and eIF5. This complex mediates recruitment of the 40S subunit to mRNA.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0070916	biolink:NamedThing	inositol phosphoceramide synthase complex	A protein complex that possesses inositol phosphoceramide synthase activity and contains a catalytic subunit and a regulatory subunit (Aur1p and Kei1p, respectively, in Saccharomyces).	tmpzr1t_l9r_go_relaxed.owl	IPC synthase complex							mah	2009-09-10T05:23:21Z					cellular_component											owl:Class	
GO:0051335	biolink:NamedThing	meiosis II nuclear membrane reassembly	The reformation of the nuclear membrane during meiosis II.	tmpzr1t_l9r_go_relaxed.owl	meiosis II nuclear envelope reassembly	https://github.com/geneontology/go-ontology/issues/20636												biological_process											owl:Class	
GO:0097574	biolink:NamedThing	lateral part of cell	The region of a polarized cell other than its tips or ends (in some cell types, one end may be called the apex and the other the base). For example, in a polarized epithelial cell, the lateral part includes the cell sides which interface adjacent cells.	tmpzr1t_l9r_go_relaxed.owl								pr	2014-02-26T13:27:27Z					cellular_component											owl:Class	
GO:0032625	biolink:NamedThing	interleukin-21 production	The appearance of interleukin-21 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	tmpzr1t_l9r_go_relaxed.owl	IL-21 production|interleukin-21 biosynthetic process|interleukin-21 secretion											GO:0072619|GO:0042238		biological_process											owl:Class	
GO:0005140	biolink:NamedThing	interleukin-9 receptor binding	Binding to an interleukin-9 receptor.	tmpzr1t_l9r_go_relaxed.owl	IL-9|interleukin-9 receptor ligand													molecular_function											owl:Class	
GO:0006546	biolink:NamedThing	glycine catabolic process	The chemical reactions and pathways resulting in the breakdown of glycine, aminoethanoic acid.	tmpzr1t_l9r_go_relaxed.owl	glycine catabolism|glycine breakdown|glycine degradation													biological_process											owl:Class	
GO:1901695	biolink:NamedThing	tyramine biosynthetic process	The chemical reactions and pathways resulting in the formation of tyramine.	tmpzr1t_l9r_go_relaxed.owl	tyramine formation|tyramine synthesis|tyramine biosynthesis|tyramine anabolism							tb	2012-12-12T19:31:35Z					biological_process											owl:Class	
GO:0007406	biolink:NamedThing	negative regulation of neuroblast proliferation	Any process that stops, prevents, or reduces the frequency, rate or extent of the proliferation of neuroblasts.	tmpzr1t_l9r_go_relaxed.owl	suppression of neuroblast proliferation|down-regulation of neuroblast proliferation|downregulation of neuroblast proliferation|down regulation of neuroblast proliferation|inhibition of neuroblast proliferation													biological_process											owl:Class	
GO:0033582	biolink:NamedThing	protein galactosylation in cytosol	The addition of a galactose unit to a protein amino acid in the cytosol.	tmpzr1t_l9r_go_relaxed.owl	protein amino acid galactosylation in cytosol													biological_process											owl:Class	
GO:0042125	biolink:NamedThing	protein galactosylation	The addition of a galactose molecule to a protein amino acid.	tmpzr1t_l9r_go_relaxed.owl	protein amino acid galactosylation													biological_process											owl:Class	
GO:0102847	biolink:NamedThing	1-18:3-2-16:2-monogalactosyldiacylglycerol desaturase activity	Catalysis of the reaction: 1-18:3-2-16:2-monogalactosyldiacylglycerol + O2 + a reduced electron acceptor <=> 1-18:3-2-16:3-monogalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-8309									molecular_function											owl:Class	
GO:0035797	biolink:NamedThing	tellurite methyltransferase activity	Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to tellurite [TeO3(2-)]. Methylated derivatives of tellurite include Te(CH3)2 (dimethyltelluride) and Te2(CH3)2 (dimethylditelluride).	tmpzr1t_l9r_go_relaxed.owl	S-adenosyl-L-methionine-dependent tellurite methyltransferase activity|tellurite methylase activity|SAM-dependent tellurite methyltransferase activity							bf	2011-04-14T01:06:19Z					molecular_function											owl:Class	
GO:1902776	biolink:NamedThing	6-sulfoquinovose(1-) metabolic process	The chemical reactions and pathways involving 6-sulfoquinovose(1-).	tmpzr1t_l9r_go_relaxed.owl	6-sulfoquinovose(1-) metabolism							dph	2014-03-18T17:45:56Z					biological_process											owl:Class	
GO:0042179	biolink:NamedThing	nicotine biosynthetic process	The chemical reactions and pathways resulting in the formation of nicotine, (S)(-)-3-(1-methyl-2-pyrrolidinyl)pyridine.	tmpzr1t_l9r_go_relaxed.owl	nicotine biosynthesis|nicotine formation|nicotine anabolism|nicotine synthesis													biological_process											owl:Class	
GO:1905647	biolink:NamedThing	proline import across plasma membrane	The directed movement of proline from outside of a cell into the cytoplasmic compartment.	tmpzr1t_l9r_go_relaxed.owl	proline import into cell							mah	2014-03-31T13:14:04Z			GO:1902825		biological_process											owl:Class	
GO:0015766	biolink:NamedThing	disaccharide transport	The directed movement of disaccharides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Disaccharides are sugars composed of two monosaccharide units.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0032396	biolink:NamedThing	inhibitory MHC class I receptor activity	Combining with a MHC class I protein complex to mediate signaling that inhibits activation of a lymphocyte.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0032393	biolink:NamedThing	MHC class I receptor activity	Combining with an MHC class I protein complex to initiate a change in cellular activity. Class I here refers to classical class I molecules.	tmpzr1t_l9r_go_relaxed.owl	T cell receptor activity|alpha-beta T cell receptor activity|gamma-delta T cell receptor activity					Note that this term is intended for annotation of gene products that act as receptors for MHC class I protein complexes, not for components of the MHC class I protein complexes themselves.								molecular_function											owl:Class	
GO:0032140	biolink:NamedThing	single adenine insertion binding	Binding to a double-stranded DNA region containing a single adenine insertion or a deletion that results in an unpaired adenine.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1902937	biolink:NamedThing	inward rectifier potassium channel complex	A protein complex which is capable of inward rectifier potassium channel activity.	tmpzr1t_l9r_go_relaxed.owl						An example of this is Kcnj2 in mouse (P35561) in PMID:16834334 (inferred from direct assay).		bhm	2014-04-25T15:18:41Z					cellular_component											owl:Class	
GO:0035874	biolink:NamedThing	cellular response to copper ion starvation	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of copper ions.	tmpzr1t_l9r_go_relaxed.owl	cellular response to copper starvation							bf	2011-05-31T09:28:47Z					biological_process											owl:Class	
GO:0031148	biolink:NamedThing	DIF-1 biosynthetic process	The chemical reactions and pathways resulting in the formation of 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one, also known as DIF-1, differentiation-inducing factor-1. DIF-1 is a secreted chlorinated molecule that controls cell fate during development of Dictyostelium cells.	tmpzr1t_l9r_go_relaxed.owl	1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one biosynthetic process|1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one formation|1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one anabolism|1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one biosynthesis|DIF-1 biosynthesis|1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one synthesis													biological_process											owl:Class	
GO:0019980	biolink:NamedThing	interleukin-5 binding	Binding to interleukin-5.	tmpzr1t_l9r_go_relaxed.owl	IL-5 binding													molecular_function											owl:Class	
GO:1900774	biolink:NamedThing	fumiquinazoline catabolic process	The chemical reactions and pathways resulting in the breakdown of fumiquinazoline.	tmpzr1t_l9r_go_relaxed.owl	fumiquinazolines degradation|fumiquinazoline degradation|fumiquinazolines catabolic process|fumiquinazolines catabolism|fumiquinazoline catabolism|fumiquinazolines breakdown|fumiquinazoline breakdown							di	2012-06-04T09:29:46Z					biological_process											owl:Class	
GO:0070151	biolink:NamedThing	mitochondrial histidyl-tRNA aminoacylation	The process of coupling histidine to histidyl-tRNA in a mitochondrion, catalyzed by histidyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0006427	biolink:NamedThing	histidyl-tRNA aminoacylation	The process of coupling histidine to histidyl-tRNA, catalyzed by histidyl-tRNA synthetase. The histidyl-tRNA synthetase is a  class-II synthetase. The activated amino acid is transferred to the 3''-OH group of a histidine-accetping tRNA.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0043139	biolink:NamedThing	5'-3' DNA helicase activity	Unwinding a DNA helix in the 5' to 3' direction, driven by ATP hydrolysis.	tmpzr1t_l9r_go_relaxed.owl	ATP-dependent 5'-3' DNA helicase activity|ATP-dependent 5' to 3' DNA helicase activity|5' to 3' DNA helicase activity|DNA helicase IV activity				Reactome:R-HSA-6782131							GO:0008722|GO:0043141		molecular_function											owl:Class	
GO:0060476	biolink:NamedThing	protein localization involved in acrosome reaction	The actin-based process in which a protein is transported to, or maintained in, a specific location in the sperm as part of the acrosome reaction.	tmpzr1t_l9r_go_relaxed.owl	protein localisation involved in acrosome reaction													biological_process											owl:Class	
GO:0047882	biolink:NamedThing	estradiol 6-beta-monooxygenase activity	Catalysis of the reaction: AH(2) + estradiol-17beta + O(2) = 6beta-hydroxyestradiol-17beta + A + H(2)O.	tmpzr1t_l9r_go_relaxed.owl	estradiol 6b-hydroxylase activity|estradiol 6beta-monooxygenase activity|estradiol-17beta,hydrogen-donor:oxygen oxidoreductase (6beta-hydroxylating)|estradiol 6b-monooxygenase activity|estradiol 6beta-hydroxylase activity|estradiol 6-beta-hydroxylase activity				MetaCyc:ESTRADIOL-6-BETA-MONOOXYGENASE-RXN|KEGG_REACTION:R03086|EC:1.14.99.11|RHEA:19137									molecular_function											owl:Class	
GO:0033518	biolink:NamedThing	myo-inositol hexakisphosphate dephosphorylation	The process of removing one or more phosphate group from myo-inositol hexakisphosphate.	tmpzr1t_l9r_go_relaxed.owl	phytate dephosphorylation				MetaCyc:PWY-4702|MetaCyc:PWY-4781									biological_process											owl:Class	
GO:0002839	biolink:NamedThing	positive regulation of immune response to tumor cell	Any process that activates or increases the frequency, rate, or extent of an immune response to tumor cell.	tmpzr1t_l9r_go_relaxed.owl	up regulation of immune response to tumor cell|activation of immune response to tumor cell|positive regulation of immune response to tumour cell|stimulation of immune response to tumor cell|upregulation of immune response to tumor cell|up-regulation of immune response to tumor cell													biological_process											owl:Class	
GO:0071788	biolink:NamedThing	endoplasmic reticulum tubular network maintenance	The organization process that preserves the endoplasmic reticulum (ER) tubular network in a stable functional or structural state. The ER tubular network is the ER part that comprises the membranes with high curvature in cross-section.	tmpzr1t_l9r_go_relaxed.owl	ER tubular network maintenance							mah	2010-09-01T01:55:06Z					biological_process											owl:Class	
GO:0071786	biolink:NamedThing	endoplasmic reticulum tubular network organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endoplasmic reticulum (ER) tubular network. The ER tubular network is the ER part that that has membranes with high curvature in cross-section.	tmpzr1t_l9r_go_relaxed.owl	endoplasmic reticulum tubular network organisation|ER tubular network organization|ER tubular network organisation							mah	2010-09-01T01:53:51Z					biological_process											owl:Class	
GO:2000867	biolink:NamedThing	regulation of estrone secretion	Any process that modulates the frequency, rate or extent of estrone secretion.	tmpzr1t_l9r_go_relaxed.owl	regulation of folliculin secretion|regulation of 3-hydroxy-1,3,5(10)-estratrien-17-one secretion							bf	2011-07-26T08:50:11Z					biological_process											owl:Class	
GO:0009851	biolink:NamedThing	auxin biosynthetic process	The chemical reactions and pathways resulting in the formation of auxins, plant hormones that regulate aspects of plant growth.	tmpzr1t_l9r_go_relaxed.owl	auxin synthesis|auxin anabolism|auxin formation|auxin biosynthesis													biological_process											owl:Class	
GO:0042446	biolink:NamedThing	hormone biosynthetic process	The chemical reactions and pathways resulting in the formation of any hormone, naturally occurring substances secreted by specialized cells that affects the metabolism or behavior of other cells possessing functional receptors for the hormone.	tmpzr1t_l9r_go_relaxed.owl	hormone synthesis|hormone anabolism|hormone formation|hormone biosynthesis													biological_process											owl:Class	
GO:0032669	biolink:NamedThing	regulation of interleukin-25 production	Any process that modulates the frequency, rate, or extent of interleukin-25 production.	tmpzr1t_l9r_go_relaxed.owl	regulation of IL-25 production|regulation of interleukin-25 biosynthetic process|regulation of interleukin-25 secretion							bc	2019-12-09T16:51:07Z			GO:0150148|GO:0045529		biological_process											owl:Class	
GO:0032782	biolink:NamedThing	bile acid secretion	The regulated release of bile acid, composed of any of a group of steroid carboxylic acids occurring in bile, by a cell or a tissue.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0050036	biolink:NamedThing	L-threonate 3-dehydrogenase activity	Catalysis of the reaction: L-threonate + NAD(+) = 3-dehydro-L-threonate + H(+) + NADH.	tmpzr1t_l9r_go_relaxed.owl	L-threonic acid dehydrogenase activity|threonate dehydrogenase activity|L-threonate:NAD+ 3-oxidoreductase activity				KEGG_REACTION:R03733|EC:1.1.1.129|MetaCyc:L-THREONATE-3-DEHYDROGENASE-RXN|RHEA:23376									molecular_function											owl:Class	
GO:0050313	biolink:NamedThing	sulfur dioxygenase activity	Catalysis of the reaction: sulfur + O2 + H2O = sulfite.	tmpzr1t_l9r_go_relaxed.owl	sulfur oxygenase activity|S-sulfanylglutathione:oxygen oxidoreductase activity|sulfur:oxygen oxidoreductase activity|sulphur dioxygenase activity				Reactome:R-HSA-1614605|RHEA:12981|MetaCyc:FESGSHTHIO-RXN|EC:1.13.11.18									molecular_function											owl:Class	
GO:0033515	biolink:NamedThing	L-lysine catabolic process using lysine 6-aminotransferase	The chemical reactions and pathways resulting in the breakdown of L-lysine into other compounds, including alpha-aminoadipate; in this pathway, L-lysine is converted to 2-aminoadipate-6-semialdehyde by lysine 6-aminotransferase.	tmpzr1t_l9r_go_relaxed.owl	L-lysine degradation using lysine 6-aminotransferase|L-lysine breakdown using lysine 6-aminotransferase				MetaCyc:PWY-5298									biological_process											owl:Class	
GO:0019474	biolink:NamedThing	L-lysine catabolic process to acetyl-CoA	The chemical reactions and pathways resulting in the breakdown of L-lysine into other compounds, including acetyl-CoA.	tmpzr1t_l9r_go_relaxed.owl	L-lysine degradation to acetyl-CoA|L-lysine breakdown to acetyl-CoA													biological_process											owl:Class	
GO:0002017	biolink:NamedThing	regulation of blood volume by renal aldosterone	The process in which the hormone aldosterone decreases the rate of diuresis and natriuresis resulting in increased blood volume.	tmpzr1t_l9r_go_relaxed.owl	renal regulation of blood volume by aldosterone|aldosterone mediated control of body fluids|aldosterone mediated regulation of blood volume													biological_process											owl:Class	
GO:0001977	biolink:NamedThing	renal system process involved in regulation of blood volume	A slow mechanism of blood pressure regulation that responds to changes in pressure resulting from fluid and salt intake by modulating the quantity of blood in the circulatory system.	tmpzr1t_l9r_go_relaxed.owl	renal regulation of blood volume|renal blood volume control of blood pressure													biological_process											owl:Class	
GO:0021545	biolink:NamedThing	cranial nerve development	The process whose specific outcome is the progression of the cranial nerves over time, from its formation to the mature structure. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1905449	biolink:NamedThing	regulation of Fc-gamma receptor signaling pathway involved in phagocytosis	Any process that modulates the frequency, rate or extent of Fc-gamma receptor signaling pathway involved in phagocytosis.	tmpzr1t_l9r_go_relaxed.owl	regulation of Fc gamma receptor-dependent phagocytosis|regulation of Fc-gamma receptor signalling pathway involved in phagocytosis|regulation of Fcgamma receptor-mediated phagocytosis|regulation of IgG-mediated phagocytosis							sl	2016-09-15T19:41:50Z					biological_process											owl:Class	
GO:0060368	biolink:NamedThing	regulation of Fc receptor mediated stimulatory signaling pathway	Any process that modulates the rate, frequency or extent of the Fc receptor mediated stimulatory signaling pathway. The Fc receptor mediated stimulatory signaling pathway is a series of molecular signals generated as a consequence of a the binding of the Fc portion of an immunoglobulin by an Fc receptor capable of activating or perpetuating an immune response. The Fc portion of an immunoglobulin is its C-terminal constant region.	tmpzr1t_l9r_go_relaxed.owl	regulation of Fc receptor mediated stimulatory signalling pathway													biological_process											owl:Class	
GO:0033436	biolink:NamedThing	AUG codon-amino acid adaptor activity	A triplet codon-amino acid adaptor activity that recognizes an AUG codon.	tmpzr1t_l9r_go_relaxed.owl	ATG codon-amino acid adaptor activity|initiator methionine tRNA|methionine tRNA					Note that in the standard genetic code, ATG codes for methionine, and is the initiator codon.								molecular_function											owl:Class	
GO:0047154	biolink:NamedThing	methylmalonyl-CoA carboxytransferase activity	Catalysis of the reaction: pyruvate + D-methylmalonyl-CoA = oxaloacetic acid + propionyl-CoA.	tmpzr1t_l9r_go_relaxed.owl	methylmalonyl coenzyme A carboxyltransferase activity|transcarboxylase activity|oxalacetic transcarboxylase activity|(S)-2-methyl-3-oxopropanoyl-CoA:pyruvate carboxyltransferase activity|methylmalonyl-CoA transcarboxylase activity|(S)-methylmalonyl-CoA:pyruvate carboxytransferase activity|(S)-methylmalonyl-CoA:pyruvate carboxyltransferase activity|methylmalonyl-CoA carboxyltransferase activity|(S)-2-methyl-3-oxopropanoyl-CoA:pyruvate				UM-BBD_reactionID:r0923|RHEA:20764|EC:2.1.3.1|MetaCyc:2.1.3.1-RXN									molecular_function											owl:Class	
GO:1903526	biolink:NamedThing	negative regulation of membrane tubulation	Any process that stops, prevents or reduces the frequency, rate or extent of membrane tubulation.	tmpzr1t_l9r_go_relaxed.owl	inhibition of membrane tubulation|downregulation of plasma membrane tubulation|downregulation of membrane tubulation|down regulation of membrane tubulation|down regulation of plasma membrane tubulation|inhibition of plasma membrane tubulation|negative regulation of plasma membrane tubulation|down-regulation of plasma membrane tubulation|down-regulation of membrane tubulation							pm	2014-10-07T12:52:45Z					biological_process											owl:Class	
GO:1903043	biolink:NamedThing	positive regulation of chondrocyte hypertrophy	Any process that activates or increases the frequency, rate or extent of chondrocyte hypertrophy.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of chondrocyte hypertrophy|upregulation of chondrocyte hypertrophy|up regulation of chondrocyte hypertrophy|activation of chondrocyte hypertrophy							mr	2014-05-20T21:23:25Z					biological_process											owl:Class	
GO:0061523	biolink:NamedThing	cilium disassembly	A cellular process that results in the breakdown of a cilium.	tmpzr1t_l9r_go_relaxed.owl	cilium resorption					Note that we deem cilium and microtubule-based flagellum to be equivalent.		dph	2013-04-18T14:59:59Z					biological_process											owl:Class	
GO:0044782	biolink:NamedThing	cilium organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cilium, a specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole.	tmpzr1t_l9r_go_relaxed.owl	microtubule-based flagellum organization					Note that we deem cilium and microtubule-based flagellum to be equivalent.		jl	2013-03-27T15:09:58Z					biological_process											owl:Class	
GO:1903904	biolink:NamedThing	negative regulation of establishment of T cell polarity	Any process that stops, prevents or reduces the frequency, rate or extent of establishment of T cell polarity.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of T-cell polarization|down-regulation of establishment of T lymphocyte polarity|inhibition of establishment of T lymphocyte polarity|downregulation of T lymphocyte polarization|inhibition of establishment of T cell polarity|inhibition of T-cell polarization|down regulation of T cell polarization|negative regulation of T lymphocyte polarization|inhibition of T lymphocyte polarization|down-regulation of establishment of T-lymphocyte polarity|down regulation of T-cell polarization|inhibition of establishment of T-cell polarity|negative regulation of T cell polarization|negative regulation of establishment of T lymphocyte polarity|down regulation of establishment of T-cell polarity|negative regulation of establishment of T-lymphocyte polarity|negative regulation of T-cell polarization|down-regulation of establishment of T cell polarity|down-regulation of establishment of T-cell polarity|down-regulation of T lymphocyte polarization|downregulation of establishment of T cell polarity|down-regulation of T cell polarization|down regulation of establishment of T lymphocyte polarity|downregulation of T-cell polarization|down regulation of establishment of T-lymphocyte polarity|inhibition of T cell polarization|inhibition of establishment of T-lymphocyte polarity|down regulation of T lymphocyte polarization|downregulation of establishment of T-cell polarity|downregulation of T cell polarization|down regulation of establishment of T cell polarity|negative regulation of establishment of T-cell polarity|downregulation of establishment of T lymphocyte polarity|downregulation of establishment of T-lymphocyte polarity							als	2015-02-09T10:50:30Z					biological_process											owl:Class	
GO:0050868	biolink:NamedThing	negative regulation of T cell activation	Any process that stops, prevents, or reduces the frequency, rate or extent of T cell activation.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of T cell activation|negative regulation of T lymphocyte activation|inhibition of T cell activation|negative regulation of T-cell activation|down regulation of T cell activation|negative regulation of T-lymphocyte activation|downregulation of T cell activation													biological_process											owl:Class	
GO:1905700	biolink:NamedThing	negative regulation of xenobiotic detoxification by transmembrane export across the plasma membrane	Any process that stops, prevents or reduces the frequency, rate or extent of xenobiotic transmembrane export. A xenobiotic is a compound foreign to the organim exposed to it. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of drug transmembrane export|negative regulation of drug transmembrane export|inhibition of drug transmembrane export|negative regulation of xenobiotic transmembrane export|down regulation of drug transmembrane export|downregulation of drug transmembrane export	https://github.com/geneontology/go-ontology/issues/19460|https://github.com/geneontology/go-ontology/issues/17083						sl	2016-11-15T16:46:36Z					biological_process											owl:Class	
GO:0050878	biolink:NamedThing	regulation of body fluid levels	Any process that modulates the levels of body fluids.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0035899	biolink:NamedThing	negative regulation of blood coagulation in other organism	Any process in which an organism stops, prevents or reduces the frequency, rate or extent of blood coagulation in another organism. Blood coagulation is the sequential process in which the multiple coagulation factors of the blood interact, ultimately resulting in the formation of an insoluble fibrin clot.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of blood coagulation in other organism|suppression of blood coagulation in other organism|negative regulation of blood clotting in other organism|downregulation of blood coagulation in other organism|inhibition of blood coagulation in other organism							bf	2011-06-22T09:17:54Z					biological_process											owl:Class	
GO:0072726	biolink:NamedThing	response to CCCP	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a CCCP stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to carbonyl cyanide m-chlorophenyl hydrazone							mah	2012-05-31T11:16:38Z					biological_process											owl:Class	
GO:0031995	biolink:NamedThing	insulin-like growth factor II binding	Binding to insulin-like growth factor II.	tmpzr1t_l9r_go_relaxed.owl	IGF-II binding													molecular_function											owl:Class	
GO:0005520	biolink:NamedThing	insulin-like growth factor binding	Binding to an insulin-like growth factor, any member of a group of polypeptides that are structurally homologous to insulin and share many of its biological activities, but are immunologically distinct from it.	tmpzr1t_l9r_go_relaxed.owl	IGF binding													molecular_function											owl:Class	
GO:0070803	biolink:NamedThing	negative regulation of metula development	Any process that stops, prevents, or reduces the frequency, rate or extent of metula development, a process that leads to the formation of metulae. Metulae are elongated mononucleate cells that bud from the surface of the conidiophore tip.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-07-08T04:38:04Z					biological_process											owl:Class	
GO:0070802	biolink:NamedThing	regulation of metula development	Any process that modulates the frequency, rate or extent of metula development, a process that leads to the formation of metulae. Metulae are elongated mononucleate cells that bud from the surface of the conidiophore tip.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-07-08T04:14:34Z					biological_process											owl:Class	
GO:0005586	biolink:NamedThing	collagen type III trimer	A collagen homotrimer of alpha1(III) chains; type III collagen triple helices associate to form fibrils.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0031525	biolink:NamedThing	menthol biosynthetic process	The chemical reactions and pathways resulting in the formation of menthol, the monoterpene 2-isopropyl-5-methylcyclohexanol.	tmpzr1t_l9r_go_relaxed.owl	menthol anabolism|menthol synthesis|menthol biosynthesis|menthol formation													biological_process											owl:Class	
GO:0042444	biolink:NamedThing	phenylethylamine biosynthetic process	The chemical reactions and pathways resulting in the formation of phenylethylamine, an amine with pharmacological properties similar to those of amphetamine, occurs naturally as a neurotransmitter in the brain, and is present in chocolate and oil of bitter almonds.	tmpzr1t_l9r_go_relaxed.owl	phenylethylamine synthesis|phenylethylamine anabolism|phenylethylamine formation|phenylethylamine biosynthesis													biological_process											owl:Class	
GO:0019427	biolink:NamedThing	acetyl-CoA biosynthetic process from acetate	The chemical reactions and pathways resulting in the formation of acetyl-CoA from acetate, either directly or via acetylphosphate.	tmpzr1t_l9r_go_relaxed.owl	acetyl-CoA anabolism from acetate|acetyl-CoA synthesis from acetate|acetyl-CoA formation from acetate|acetate utilization				MetaCyc:ACETATEUTIL-PWY									biological_process											owl:Class	
GO:0004378	biolink:NamedThing	GDP-Man:Man1GlcNAc2-PP-Dol alpha-1,3-mannosyltransferase activity	Catalysis of the reaction: beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-diphosphodolichol + GDP-alpha-D-mannose = alpha-D-Man-(1->3)-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-diphosphodolichol + GDP + H+. This reaction is the transfer of an alpha-D-mannosyl residue from GDP-mannose into lipid-linked oligosaccharide, forming an alpha-(1->3)-D-mannosyl-D-mannose linkage.	tmpzr1t_l9r_go_relaxed.owl	GDP-mannose:glycolipid 1,3-alpha-D-mannosyltransferase activity|GDP-D-mannose:D-Man-beta-(1->4)-D-GlcNAc-beta-(1->4)-D-GlcNAc-diphosphodolichol 3-alpha-mannosyltransferase activity|glycolipid 3-alpha-mannosyltransferase activity|guanosine diphosphomannose-oligosaccharide-lipid II mannosyltransferase activity|mannosyltransferase II activity|GDP-mannose-oligosaccharide-lipid mannosyltransferase II				EC:2.4.1.132|RHEA:29515|MetaCyc:2.4.1.132-RXN									molecular_function											owl:Class	
GO:0004376	biolink:NamedThing	glycolipid mannosyltransferase activity	Catalysis of the transfer of an alpha-D-mannosyl residue from GDP-mannose into lipid-linked oligosaccharide, forming an alpha-D-mannosyl-D-mannose linkage.	tmpzr1t_l9r_go_relaxed.owl	glycolipid mannosyl transferase activity				Reactome:R-HSA-162873|Reactome:R-HSA-162821							GO:0004580		molecular_function											owl:Class	
GO:1902435	biolink:NamedThing	regulation of male mating behavior	Any process that modulates the frequency, rate or extent of male mating behavior.	tmpzr1t_l9r_go_relaxed.owl								mm2	2013-10-09T15:49:56Z					biological_process											owl:Class	
GO:0008706	biolink:NamedThing	6-phospho-beta-glucosidase activity	Catalysis of the reaction: 6-phospho-beta-D-glucoside-(1,4)-D-glucose + H2O = D-glucose 6-phosphate + glucose.	tmpzr1t_l9r_go_relaxed.owl	phospho-beta-glucosidase A|phospho-beta-glucosidase activity|6-phospho-beta-D-glucosyl-(1,4)-D-glucose glucohydrolase activity|phosphocellobiase activity				RHEA:10772|EC:3.2.1.86|MetaCyc:6-PHOSPHO-BETA-GLUCOSIDASE-RXN									molecular_function											owl:Class	
GO:1905090	biolink:NamedThing	negative regulation of parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization	Any process that stops, prevents or reduces the frequency, rate or extent of parkin-mediated mitophagy in response to mitochondrial depolarization.	tmpzr1t_l9r_go_relaxed.owl	down regulation of parkin-mediated mitophagy in response to mitochondrial depolarization|down-regulation of parkin-mediated mitophagy in response to mitochondrial depolarization|negative regulation of Park2-mediated stimulation of mitophagy in response to mitochondrial depolarization|downregulation of parkin-mediated mitophagy in response to mitochondrial depolarization|inhibition of parkin-mediated mitophagy in response to mitochondrial depolarization|negative regulation of PRKN-mediated stimulation of mitophagy in response to mitochondrial depolarization							pad	2016-03-30T15:34:38Z					biological_process											owl:Class	
GO:1905089	biolink:NamedThing	regulation of parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization	Any process that modulates the frequency, rate or extent of a parkin-mediated process that positively regulates mitophagy in response to mitochondrial depolarization.	tmpzr1t_l9r_go_relaxed.owl	regulation of PRKN-mediated stimulation of mitophagy in response to mitochondrial depolarization|regulation of Park2-mediated stimulation of mitophagy in response to mitochondrial depolarization							pad	2016-03-30T15:34:29Z					biological_process											owl:Class	
GO:0071984	biolink:NamedThing	maintenance of reproductive diapause	The dormancy process that results an organism remaining in reproductive diapause. Reproductive diapause is a form of diapause where the organism itself will remain fully active, including feeding and other routine activities, but the reproductive organs experience a tissue-specific reduction in metabolism, with characteristic triggering and releasing stimuli.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-10-21T04:49:28Z					biological_process											owl:Class	
GO:1990649	biolink:NamedThing	inositol-1,2,4,5-tetrakisphosphate 5-phosphatase activity	Catalysis of the reaction: 1D-myo-inositol 1,2,4,5-tetrakisphosphate + H2O = 1D-myo-inositol 1,2,4-trisphosphate + phosphate.	tmpzr1t_l9r_go_relaxed.owl								al	2015-02-23T11:12:10Z					molecular_function											owl:Class	
GO:0052743	biolink:NamedThing	inositol tetrakisphosphate phosphatase activity	Catalysis of the reaction: myo-inositol tetrakisphosphate + H2O = myo-inositol trisphosphate + phosphate.	tmpzr1t_l9r_go_relaxed.owl								ai	2011-09-14T01:31:39Z					molecular_function											owl:Class	
GO:0031370	biolink:NamedThing	eukaryotic initiation factor 4G binding	Binding to eukaryotic initiation factor 4G, a polypeptide factor involved in the initiation of ribosome-mediated translation.	tmpzr1t_l9r_go_relaxed.owl	eIF4G binding													molecular_function											owl:Class	
GO:0031369	biolink:NamedThing	translation initiation factor binding	Binding to a translation initiation factor, any polypeptide factor involved in the initiation of ribosome-mediated translation.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0120240	biolink:NamedThing	platelet glycocalyx	The carbohydrate rich layer at the outermost periphery of a platelet.	tmpzr1t_l9r_go_relaxed.owl								krc	2020-07-27T22:44:42Z					cellular_component											owl:Class	
GO:0140244	biolink:NamedThing	regulation of translation at presynapse	Any process that regulates translation occurring at the presynapse.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/synapse/issues/210				Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.		pg	2018-07-15T09:38:33Z					biological_process											owl:Class	
GO:0000459	biolink:NamedThing	exonucleolytic trimming involved in rRNA processing	Exonucleolytic digestion of a pre-rRNA molecule in the process to generate a mature rRNA molecule.	tmpzr1t_l9r_go_relaxed.owl	exonucleolytic trimming during rRNA processing													biological_process											owl:Class	
GO:1900676	biolink:NamedThing	negative regulation of F-9775B biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of F-9775B biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	downregulation of F-9775B biosynthetic process|down-regulation of F-9775B synthesis|inhibition of F-9775B anabolism|down-regulation of F-9775B biosynthetic process|down regulation of F-9775B formation|down regulation of F-9775B biosynthesis|negative regulation of F-9775B anabolism|negative regulation of F-9775B formation|down-regulation of F-9775B biosynthesis|downregulation of F-9775B synthesis|downregulation of F-9775B formation|inhibition of F-9775B synthesis|downregulation of F-9775B anabolism|negative regulation of F-9775B synthesis|negative regulation of F-9775B biosynthesis|down regulation of F-9775B anabolism|downregulation of F-9775B biosynthesis|inhibition of F-9775B biosynthetic process|inhibition of F-9775B formation|down-regulation of F-9775B formation|inhibition of F-9775B biosynthesis|down-regulation of F-9775B anabolism|down regulation of F-9775B biosynthetic process|down regulation of F-9775B synthesis							di	2012-05-22T04:26:53Z					biological_process											owl:Class	
GO:0043853	biolink:NamedThing	methanol-CoM methyltransferase complex	A heterotrimeric protein complex composed of a methanol methyltransferase subunit, a corrinoid protein and a methanol-specific corrinoid:coenzyme M methyltransferase subunit. Catalyzes the transfer of a methyl group from methanol to coenzyme M as part of the pathway of methanogenesis from methanol.	tmpzr1t_l9r_go_relaxed.owl	methanol: coenzyme M methyltransferase complex|methanol:CoM methyltransferase complex|methanol: CoM methyltransferase complex|methanol-coenzyme M methyltransferase complex|methanol:coenzyme M methyltransferase complex				MetaCyc:CPLX-421									cellular_component											owl:Class	
GO:0035168	biolink:NamedThing	larval lymph gland hemocyte differentiation	The process in which a relatively unspecialized cell derived from the larval lymph gland acquires the specialized features of a mature hemocyte. The lymph gland consists of three to six bilaterally paired lobes that are attached to the cardioblasts during larval stages, and it degenerates during pupal stages. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. An example of this process is found in Drosophila melanogaster.	tmpzr1t_l9r_go_relaxed.owl	larval lymph gland arthropod blood cell differentiation													biological_process											owl:Class	
GO:1905321	biolink:NamedThing	negative regulation of mesenchymal stem cell migration	Any process that stops, prevents or reduces the frequency, rate or extent of mesenchymal stem cell migration.	tmpzr1t_l9r_go_relaxed.owl	downregulation of mesenchymal stem cell migration|down-regulation of mesenchymal stem cell migration|down regulation of mesenchymal stem cell migration|inhibition of mesenchymal stem cell migration							sl	2016-07-15T22:19:22Z					biological_process											owl:Class	
GO:0015367	biolink:NamedThing	oxoglutarate:malate antiporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: oxoglutarate(out) + malate(in) = oxoglutarate(in) + malate(out).	tmpzr1t_l9r_go_relaxed.owl	2-oxoglutarate/malate carrier protein				Reactome:R-HSA-376851|Reactome:R-HSA-198440									molecular_function											owl:Class	
GO:0015140	biolink:NamedThing	malate transmembrane transporter activity	Enables the transfer of malate from one side of a membrane to the other. Malate is a chiral hydroxydicarboxylic acid, hydroxybutanedioic acid. The (+) enantiomer is an important intermediate in metabolism as a component of both the TCA cycle and the glyoxylate cycle.	tmpzr1t_l9r_go_relaxed.owl	dicarboxylate (succinate/fumarate/malate) antiporter activity													molecular_function											owl:Class	
GO:0035185	biolink:NamedThing	preblastoderm mitotic cell cycle	The first nine mitotic division cycles of the insect embryo, during which the dividing nuclei lie deep in the interior of the egg and divide nearly synchronously. This is the first phase of the syncytial period where nuclei divide in a common cytoplasm without cytokinesis.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0010089	biolink:NamedThing	xylem development	The formation of the principal water-conducting tissue of a vascular plant.	tmpzr1t_l9r_go_relaxed.owl	xylem histogenesis													biological_process											owl:Class	
GO:0010087	biolink:NamedThing	phloem or xylem histogenesis	The process whose specific outcome is the progression of phloem and/or xylem over time, from formation to the mature structure. An example of this process is found in Arabidopsis thaliana.	tmpzr1t_l9r_go_relaxed.owl	vascular tissue development|vascular tissue histogenesis													biological_process											owl:Class	
GO:0002001	biolink:NamedThing	renin secretion into blood stream	The regulated release of renin into the blood stream by juxtoglomerular cells.	tmpzr1t_l9r_go_relaxed.owl	renin release into blood stream													biological_process											owl:Class	
GO:0046188	biolink:NamedThing	methane catabolic process	The chemical reactions and pathways resulting in the breakdown of methane, a colorless, odorless, flammable gas with the formula CH4. It is the simplest of the alkanes.	tmpzr1t_l9r_go_relaxed.owl	methane catabolism|methane degradation|methane breakdown													biological_process											owl:Class	
GO:1900715	biolink:NamedThing	positive regulation of violaceol I biosynthetic process	Any process that activates or increases the frequency, rate or extent of violaceol I biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of violaceol I biosynthesis|positive regulation of violaceol I synthesis|up regulation of violaceol I biosynthesis|positive regulation of violaceol I formation|up regulation of violaceol I formation|upregulation of violaceol I synthesis|activation of violaceol I biosynthetic process|upregulation of violaceol I anabolism|activation of violaceol I synthesis|up regulation of violaceol I synthesis|upregulation of violaceol I biosynthesis|positive regulation of violaceol I anabolism|activation of violaceol I biosynthesis|upregulation of violaceol I formation|up-regulation of violaceol I anabolism|up-regulation of violaceol I biosynthetic process|activation of violaceol I formation|activation of violaceol I anabolism|up regulation of violaceol I anabolism|up regulation of violaceol I biosynthetic process|up-regulation of violaceol I biosynthesis|up-regulation of violaceol I synthesis|upregulation of violaceol I biosynthetic process|up-regulation of violaceol I formation							di	2012-05-22T05:04:41Z					biological_process											owl:Class	
GO:0051068	biolink:NamedThing	dihydrolipoamide metabolic process	The chemical reactions and pathways involving dihydrolipoamide, the reduced form of lipoamide, produced as an intermediate in the reactions in which lipoamide acts as a cofactor.	tmpzr1t_l9r_go_relaxed.owl	dihydrolipoamide metabolism|dihydrothioctamide metabolism|dihydrothioctamide metabolic process|dihydrolipoamide reduction													biological_process											owl:Class	
GO:0006481	biolink:NamedThing	C-terminal protein methylation	The methylation of the C-terminal amino acid of a protein.	tmpzr1t_l9r_go_relaxed.owl	C-terminal protein amino acid methylation													biological_process											owl:Class	
GO:0006479	biolink:NamedThing	protein methylation	The addition of a methyl group to a protein amino acid. A methyl group is derived from methane by the removal of a hydrogen atom.	tmpzr1t_l9r_go_relaxed.owl	protein amino acid methylation													biological_process											owl:Class	
GO:0044762	biolink:NamedThing	negative regulation by symbiont of host neurotransmitter secretion	Any process in which a symbiont organism negatively regulates the regulated release of a neurotransmitter from a cell in its host organism.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-12-06T15:52:20Z					biological_process											owl:Class	
GO:0044233	biolink:NamedThing	mitochondria-associated endoplasmic reticulum membrane	A zone of apposition between endoplasmic-reticulum and mitochondrial membranes, structured by bridging complexes. These contact sites are thought to facilitate inter-organelle calcium and phospholipid exchange.	tmpzr1t_l9r_go_relaxed.owl	mitochondria-associated membrane|endoplasmic reticulum-mitochondrion membrane contact site|mitochondria-associated ER membrane|mitochondria-endoplasmic reticulum (ER) contact|MAM|ER-mitochondrion membrane contact site							jl	2010-01-07T04:07:24Z					cellular_component											owl:Class	
GO:0062067	biolink:NamedThing	chloroplast photosystem I binding	Binding to a chloroplast photosystem I.	tmpzr1t_l9r_go_relaxed.owl								dph	2018-08-31T14:07:46Z					molecular_function											owl:Class	
GO:1900805	biolink:NamedThing	brevianamide F biosynthetic process	The chemical reactions and pathways resulting in the formation of brevianamide F.	tmpzr1t_l9r_go_relaxed.owl	C16H17N3O2 synthesis|cyclo-L-Trp-L-Pro anabolism|L-prolyl-L-tryptophan anhydride biosynthetic process|L-tryptophyl-L-proline cyclic anhydride biosynthetic process|cyclo-(Trp-Pro) synthesis|cyclo-L-Trp-L-Pro formation|C16H17N3O2 biosynthetic process|tryptophan-proline diketopiperazine formation|C16H17N3O2 anabolism|L-tryptophyl-L-proline cyclic anhydride synthesis|cyclo-(Trp-Pro) biosynthesis|cyclo-(Trp-Pro) biosynthetic process|brevianamide F synthesis|cyclo-L-tryptophanyl-L-proline anabolism|cyclo-L-tryptophanyl-L-proline biosynthetic process|L-prolyl-L-tryptophan anhydride formation|cyclo-L-Trp-L-Pro biosynthetic process|tryptophan-proline diketopiperazine biosynthesis|L-tryptophyl-L-proline cyclic anhydride biosynthesis|cyclo-L-Trp-L-Pro synthesis|L-tryptophyl-L-proline cyclic anhydride anabolism|L-tryptophyl-L-proline cyclic anhydride formation|cyclo-L-tryptophanyl-L-proline formation|cyclo-(Trp-Pro) anabolism|brevianamide F anabolism|tryptophan-proline diketopiperazine synthesis|C16H17N3O2 formation|tryptophan-proline diketopiperazine anabolism|cyclo-L-tryptophanyl-L-proline synthesis|brevianamide F biosynthesis|brevianamide F formation|cyclo-L-Trp-L-Pro biosynthesis|C16H17N3O2 biosynthesis|L-prolyl-L-tryptophan anhydride anabolism|cyclo-(Trp-Pro) formation|L-prolyl-L-tryptophan anhydride biosynthesis|tryptophan-proline diketopiperazine biosynthetic process|cyclo-L-tryptophanyl-L-proline biosynthesis|L-prolyl-L-tryptophan anhydride synthesis							di	2012-06-04T09:52:48Z					biological_process											owl:Class	
GO:0048011	biolink:NamedThing	neurotrophin TRK receptor signaling pathway	A series of molecular signals initiated by the binding of a neurotrophin to a receptor on the surface of the target cell where the receptor possesses tyrosine kinase activity, and ending with regulation of a downstream cellular process, e.g. transcription.	tmpzr1t_l9r_go_relaxed.owl	TrkB signaling pathway|TrkA signaling pathway|TrkC signaling pathway|tropomyosin-receptor-kinase signaling													biological_process											owl:Class	
GO:0038179	biolink:NamedThing	neurotrophin signaling pathway	A series of molecular signals initiated by the binding of a neurotrophin to a receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription. Neurotrophins are a family of secreted growth factors that induce the survival, development, and function of neurons.	tmpzr1t_l9r_go_relaxed.owl	neurotrophin receptor signaling pathway					There are two classes of receptors for neurotrophins: p75 and the Trk family of tyrosine kinase receptors.		bf	2013-03-27T17:22:44Z					biological_process											owl:Class	
GO:0006572	biolink:NamedThing	tyrosine catabolic process	The chemical reactions and pathways resulting in the breakdown of tyrosine, an aromatic amino acid, 2-amino-3-(4-hydroxyphenyl)propanoic acid.	tmpzr1t_l9r_go_relaxed.owl	tyrosine catabolism|tyrosine breakdown|tyrosine degradation													biological_process											owl:Class	
GO:0071729	biolink:NamedThing	beak morphogenesis	The process in which the anatomical structures of the beak are generated and organized. The avian beak is an external anatomical structure, in the head region, that is adapted for feeding self and young, catching prey, probing, etc. It encompasses, but is not restricted to, the maxilla, mandible, maxillary rhamphotheca, mandibular rhamphotheca, nostril, nasal fossa, nasal bones, egg tooth and rictus.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-03-17T03:54:34Z					biological_process											owl:Class	
GO:0046174	biolink:NamedThing	polyol catabolic process	The chemical reactions and pathways resulting in the breakdown of a polyol, any alcohol containing three or more hydroxyl groups attached to saturated carbon atoms.	tmpzr1t_l9r_go_relaxed.owl	polyol breakdown|polyhydric alcohol catabolic process|polyol degradation|polyol catabolism													biological_process											owl:Class	
GO:0070212	biolink:NamedThing	protein poly-ADP-ribosylation	The transfer of multiple ADP-ribose residues from NAD to a protein amino acid, forming a poly(ADP-ribose) chain.	tmpzr1t_l9r_go_relaxed.owl	protein poly(ADP-ribose) metabolism|protein amino acid poly-ADP-ribosylation|poly(ADP-ribose) addition to protein|addition of poly-ADP-ribose to protein|protein poly(ADP-ribose) synthesis													biological_process											owl:Class	
GO:0050836	biolink:NamedThing	iron incorporation into iron-sulfur cluster via tris-L-cysteinyl L-arginyl diiron disulfide	The incorporation of iron into a 4Fe-4S iron-sulfur cluster via tris-L-cysteinyl L-arginyl diiron disulfide.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0357									biological_process											owl:Class	
GO:2001304	biolink:NamedThing	lipoxin B4 metabolic process	The chemical reactions and pathways involving lipoxin B4. Lipoxin B4 is a C20 hydroxy fatty acid having (5S)-, (14R)- and (15S)-hydroxy groups as well as (6E)- (8Z)-, (10E)- and (12E)-double bonds.	tmpzr1t_l9r_go_relaxed.owl	LXB4 metabolism|lipoxin B4 metabolism|LXB4 metabolic process							bf	2012-03-07T11:14:58Z					biological_process											owl:Class	
GO:2001300	biolink:NamedThing	lipoxin metabolic process	The chemical reactions and pathways involving a lipoxin. A lipoxin is a non-classic eicosanoid and signalling molecule that has four conjugated double bonds and is derived from arachidonic acid.	tmpzr1t_l9r_go_relaxed.owl	lipoxin metabolism							bf	2012-03-07T11:11:08Z					biological_process											owl:Class	
GO:0045937	biolink:NamedThing	positive regulation of phosphate metabolic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving phosphates.	tmpzr1t_l9r_go_relaxed.owl	upregulation of phosphate metabolic process|positive regulation of phosphate metabolism|activation of phosphate metabolic process|up regulation of phosphate metabolic process|stimulation of phosphate metabolic process|up-regulation of phosphate metabolic process													biological_process											owl:Class	
GO:0050817	biolink:NamedThing	coagulation	The process in which a fluid solution, or part of it, changes into a solid or semisolid mass.	tmpzr1t_l9r_go_relaxed.owl	clotting													biological_process											owl:Class	
GO:0070511	biolink:NamedThing	negative regulation of histone H4-K20 methylation	Any process that stops, prevents, or reduces the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 20 of histone H4.	tmpzr1t_l9r_go_relaxed.owl	down regulation of histone H4-K20 methylation|down-regulation of histone H4-K20 methylation|inhibition of histone H4-K20 methylation|downregulation of histone H4-K20 methylation													biological_process											owl:Class	
GO:0046554	biolink:NamedThing	malate dehydrogenase (NADP+) activity	Catalysis of the reaction: (S)-malate + NADP+ = oxaloacetate + NADPH + H+.	tmpzr1t_l9r_go_relaxed.owl	malate NADP dehydrogenase activity|malic dehydrogenase (nicotinamide adenine dinucleotide phosphate)|NADP-malate dehydrogenase activity|(S)-malate:NADP+ oxidoreductase activity|NADP-linked malate dehydrogenase activity|NADP malate dehydrogenase activity				RHEA:10824|KEGG_REACTION:R00343|MetaCyc:MALATE-DEHYDROGENASE-NADP+-RXN|EC:1.1.1.82									molecular_function											owl:Class	
GO:0033439	biolink:NamedThing	ACA codon-amino acid adaptor activity	A triplet codon-amino acid adaptor activity that recognizes an ACA codon.	tmpzr1t_l9r_go_relaxed.owl	threonine tRNA					Note that in the standard genetic code, ACA codes for threonine.								molecular_function											owl:Class	
GO:0015157	biolink:NamedThing	oligosaccharide transmembrane transporter activity	Enables the transfer of oligosaccharide from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	endosomal oligosaccharide transporter													molecular_function											owl:Class	
GO:0002636	biolink:NamedThing	positive regulation of germinal center formation	Any process that activates or increases the frequency, rate, or extent of germinal center formation.	tmpzr1t_l9r_go_relaxed.owl	up regulation of germinal center formation|activation of germinal center formation|stimulation of germinal center formation|upregulation of germinal center formation|up-regulation of germinal center formation													biological_process											owl:Class	
GO:0140662	biolink:NamedThing	ATP-dependent protein folding chaperone	Binding to a protein or a protein-containing complex to assist the protein folding process, driven by ATP hydrolysis.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/21660						pg	2021-06-19T16:28:34Z					molecular_function											owl:Class	
GO:0032298	biolink:NamedThing	positive regulation of DNA-dependent DNA replication initiation	Any process that activates or increases the frequency, rate or extent of initiation of DNA-dependent DNA replication.	tmpzr1t_l9r_go_relaxed.owl	up regulation of DNA replication initiation|upregulation of DNA replication initiation|negative regulation of DNA replication initiation|activation of DNA replication initiation|up-regulation of DNA replication initiation|stimulation of DNA replication initiation													biological_process											owl:Class	
GO:0051292	biolink:NamedThing	nuclear pore complex assembly	The aggregation, arrangement and bonding together of a set of components to form a nuclear pore complex.	tmpzr1t_l9r_go_relaxed.owl	nuclear pore formation|nuclear pore biogenesis|nuclear pore complex biogenesis|NPC assembly|nuclear pore complex biosynthesis|nuclear pore biosynthesis|nuclear pore assembly|nuclear pore complex formation													biological_process											owl:Class	
GO:0006999	biolink:NamedThing	nuclear pore organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear pore.	tmpzr1t_l9r_go_relaxed.owl	nuclear pore organization and biogenesis|nuclear pore organisation|nuclear pore complex organization and biogenesis													biological_process											owl:Class	
GO:1903651	biolink:NamedThing	positive regulation of cytoplasmic transport	Any process that activates or increases the frequency, rate or extent of cytoplasmic transport.	tmpzr1t_l9r_go_relaxed.owl	activation of cytoplasmic transport|positive regulation of cytoplasmic streaming|upregulation of cytoplasmic transport|up regulation of cytoplasmic streaming|up-regulation of cytoplasmic streaming|up-regulation of cytoplasmic transport|activation of cytoplasmic streaming|upregulation of cytoplasmic streaming|up regulation of cytoplasmic transport							jl	2014-11-24T13:38:34Z					biological_process											owl:Class	
GO:0070974	biolink:NamedThing	POU domain binding	Binding to a POU domain of a protein. The POU domain is a bipartite DNA binding domain composed of two subunits separated by a non-conserved region of 15-55 amino acids; it is found in several eukaryotic transcription factors.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-10-02T12:53:02Z					molecular_function											owl:Class	
GO:1901832	biolink:NamedThing	all-trans-neoxanthin catabolic process	The chemical reactions and pathways resulting in the breakdown of all-trans-neoxanthin.	tmpzr1t_l9r_go_relaxed.owl	all-trans-neoxanthin breakdown|neoxanthin catabolic process|neoxanthin breakdown|neoxanthin catabolism|all-trans-neoxanthin degradation|all-trans-neoxanthin catabolism|neoxanthin degradation							yaf	2013-01-22T12:43:51Z					biological_process											owl:Class	
GO:0006273	biolink:NamedThing	lagging strand elongation	The process in which an existing DNA strand is extended in a net 3' to 5' direction by activities including the addition of nucleotides to the 3' end of the strand, complementary to an existing template, as part of DNA replication. Lagging strand DNA elongation proceeds by discontinuous synthesis of short stretches of DNA, known as Okazaki fragments, from RNA primers; these fragments are then joined by DNA ligase. Although each segment of nascent DNA is synthesized in the 5' to 3' direction, the overall direction of lagging strand synthesis is 3' to 5', mirroring the progress of the replication fork.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/12633												biological_process											owl:Class	
GO:0140327	biolink:NamedThing	flippase activity	Catalysis of the movement of lipids from the exoplasmic to the cytosolic leaftlet of a membrane, using energy from the hydrolysis of ATP.	tmpzr1t_l9r_go_relaxed.owl	flippase activity (exoplasmic to cytosolic leaftlet)					Nomenclature note. Flippases and floppases are ATP-dependent transbilayer lipid translocators. According to an extensively used, though not universal, nomenclature, they catalyze lipid transfer towards the inward monolayer (flippases) or towards the outward monolayer (floppases). Scramblases are ATP-independent, non-selective, inducing non-specific transbilayer movements across the membrane. The direction of the translocation should be taken into account for annotation (from the exoplasmic to the cytosolic leaftlet of a membrane).		pg	2019-04-29T12:51:21Z					molecular_function											owl:Class	
GO:2001303	biolink:NamedThing	lipoxin A4 biosynthetic process	The chemical reactions and pathways resulting in the formation of lipoxin A4. Lipoxin A4 is a C20 hydroxy fatty acid having (5S)-, (6R)- and (15S)-hydroxy groups as well as (7E)- (9E)-, (11Z)- and (13E)-double bonds.	tmpzr1t_l9r_go_relaxed.owl	LXA4 biosynthetic process|lipoxin A4 biosynthesis|LXA4 biosynthesis|lipoxin A4 anabolism|LXA4 synthesis|LXA4 anabolism|LXA4 formation|lipoxin A4 synthesis|lipoxin A4 formation							bf	2012-03-07T11:13:18Z					biological_process											owl:Class	
GO:0014819	biolink:NamedThing	regulation of skeletal muscle contraction	Any process that modulates the frequency, rate or extent of skeletal muscle contraction.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0035840	biolink:NamedThing	old growing cell tip	A cell tip which has existed for at least one complete cell cycle, and at which polarized growth occurs. For example, in fission yeast the cell end that existed prior to cell division grows immediately after division, and contains a distinctive complement of proteins including actin cytoskeletal structures.	tmpzr1t_l9r_go_relaxed.owl	old growing cell end							bf	2011-05-06T01:33:54Z					cellular_component											owl:Class	
GO:0035838	biolink:NamedThing	growing cell tip	The region at either end of the longest axis of a cylindrical or elongated cell, where polarized growth occurs.	tmpzr1t_l9r_go_relaxed.owl	growing cell end							bf	2011-05-06T01:28:44Z					cellular_component											owl:Class	
GO:0046962	biolink:NamedThing	sodium-transporting ATPase activity, rotational mechanism	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Na+(in) -> ADP + phosphate + Na+(out), by a rotational mechanism.	tmpzr1t_l9r_go_relaxed.owl	Na+-transporting two-sector ATPase|ATP phosphohydrolase (Na+-transporting) activity|Na(+)-translocating ATPase activity|ATP synthase, sodium ion specific activity|sodium-transporting two-sector ATPase activity|Na+-translocating F1Fo-ATPase|sodium-translocating F-type ATPase activity|Na+-translocating ATPase activity|sodium-translocating V-type ATPase activity|vacuolar-type Na+-ATPase|vacuolar-type Na+-translocating ATPase|Na(+)-transporting two-sector ATPase activity|sodium transporting ATPase activity, rotational mechanism	https://github.com/geneontology/go-ontology/issues/21796			MetaCyc:3.6.3.15-RXN|EC:7.2.2.1|RHEA:58156|RHEA:58157	Found in some halophilic or alkalophilic bacteria that functions in maintaining sodium homeostasis; similar to EC:7.1.2.2 but pumps Na(+) rather than H(+). (Source: EC:7.2.2.1)								molecular_function											owl:Class	
GO:0004396	biolink:NamedThing	hexokinase activity	Catalysis of the reaction: ATP + D-hexose = ADP + D-hexose 6-phosphate.	tmpzr1t_l9r_go_relaxed.owl	ATP-dependent hexokinase activity|hexokinase (phosphorylating)|hexokinase type I activity|ATP:D-hexose 6-phosphotransferase activity|hexokinase type II activity|hexokinase type IV|hexokinase type III activity|hexokinase type IV (glucokinase) activity|glucose ATP phosphotransferase activity|hexokinase type IV glucokinase activity|hexokinase D				MetaCyc:HEXOKINASE-RXN|RHEA:22740|EC:2.7.1.1									molecular_function											owl:Class	
GO:0014875	biolink:NamedThing	detection of muscle activity involved in regulation of muscle adaptation	The series of events by which a muscle activity stimulus is received and converted into a molecular signal. This occurs as part of the regulation of muscle adaptation.	tmpzr1t_l9r_go_relaxed.owl	detection of fatigue													biological_process											owl:Class	
GO:0014864	biolink:NamedThing	detection of muscle activity	The series of events in which a muscle activity stimulus is received by a cell and converted into a molecular signal.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0060638	biolink:NamedThing	mesenchymal-epithelial cell signaling	Any process that mediates the transfer of information from a mesenchymal cell to an epithelial cell where it is received and interpreted.	tmpzr1t_l9r_go_relaxed.owl	mesenchymal-epithelial cell signalling							dph	2009-05-19T03:59:05Z					biological_process											owl:Class	
GO:1990402	biolink:NamedThing	embryonic liver development	The process occurring during the embryonic phase whose specific outcome is the progression of the liver over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl								sl	2014-06-23T20:52:03Z					biological_process											owl:Class	
GO:0048568	biolink:NamedThing	embryonic organ development	Development, taking place during the embryonic phase, of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.	tmpzr1t_l9r_go_relaxed.owl	embryonic organogenesis													biological_process											owl:Class	
GO:0043633	biolink:NamedThing	polyadenylation-dependent RNA catabolic process	The chemical reactions and pathways resulting in the breakdown of an RNA molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3'-end of the target RNA.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0098904	biolink:NamedThing	regulation of AV node cell action potential	Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in an atrioventricular node myocyte. This typically occurs via modulation of the activity or expression of voltage-gated ion channels.	tmpzr1t_l9r_go_relaxed.owl	regulation of atrioventricular node cardiac muscle cell action potential|regulation of AV node cardiac muscle cell action potential							tb	2011-11-10T08:58:56Z					biological_process											owl:Class	
GO:1904201	biolink:NamedThing	regulation of iodide transport	Any process that modulates the frequency, rate or extent of iodide transport.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-05-08T15:19:57Z					biological_process											owl:Class	
GO:1903082	biolink:NamedThing	positive regulation of C-C chemokine receptor CCR7 signaling pathway	Any process that activates or increases the frequency, rate or extent of C-C chemokine receptor CCR7 signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	upregulation of C-C chemokine receptor CCR7 signalling pathway|up-regulation of CCR7 signaling pathway|upregulation of C-C chemokine receptor CCR7 signaling pathway|activation of C-C chemokine receptor CCR7 signalling pathway|up regulation of C-C chemokine receptor CCR7 signalling pathway|activation of C-C chemokine receptor CCR7 signaling pathway|positive regulation of C-C chemokine receptor CCR7 signalling pathway|up-regulation of C-C chemokine receptor CCR7 signaling pathway|up regulation of CCR7 signaling pathway|upregulation of CCR7 signaling pathway|up regulation of C-C chemokine receptor CCR7 signaling pathway|positive regulation of CCR7 signaling pathway|up-regulation of C-C chemokine receptor CCR7 signalling pathway|activation of CCR7 signaling pathway							rl	2014-05-29T18:33:01Z					biological_process											owl:Class	
GO:0098801	biolink:NamedThing	regulation of renal system process	Any process that modulates the frequency, rate or extent of a system process, a multicellular organismal process carried out by the renal system.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0035022	biolink:NamedThing	positive regulation of Rac protein signal transduction	Any process that activates or increases the frequency, rate or extent of Rac protein signal transduction.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of Rac protein signal transduction|up regulation of Rac protein signal transduction|stimulation of Rac protein signal transduction|upregulation of Rac protein signal transduction|activation of Rac protein signal transduction													biological_process											owl:Class	
GO:0046579	biolink:NamedThing	positive regulation of Ras protein signal transduction	Any process that activates or increases the frequency, rate or extent of Ras protein signal transduction.	tmpzr1t_l9r_go_relaxed.owl	activation of Ras protein signal transduction|up-regulation of Ras protein signal transduction|up regulation of Ras protein signal transduction|upregulation of Ras protein signal transduction|stimulation of Ras protein signal transduction													biological_process											owl:Class	
GO:0006601	biolink:NamedThing	creatine biosynthetic process	The chemical reactions and pathways resulting in the formation of creatine, N-[amino(imino)methyl]-N-methylglycine. Creatine is formed by a process beginning with amidino group transfer from L-arginine to glycine to form guanidinoacetate, followed by methyl group transfer from S-adenosyl-L-methionine to guanidinoacetate; it is then is phosphorylated to form a pool that stores high energy phosphate for the replenishment of ATP during periods of high, or fluctuating energy demand. In animals, most creatine is transported to and used in muscle.	tmpzr1t_l9r_go_relaxed.owl	creatine synthesis|creatine anabolism|creatine formation|creatine biosynthesis													biological_process											owl:Class	
GO:0003351	biolink:NamedThing	epithelial cilium movement involved in extracellular fluid movement	The directed, self-propelled movement of cilia of epithelial cells. Depending on the type of cell, there may be one or many cilia per cell. This movement is usually coordinated between many epithelial cells, and serves to move extracellular fluid.	tmpzr1t_l9r_go_relaxed.owl	cilium movement involved in fluid flow|epithelial cilium beating							dph	2009-12-03T10:08:25Z					biological_process											owl:Class	
GO:1905398	biolink:NamedThing	activated CD4-positive, alpha-beta T cell apoptotic process	Any apoptotic process in an activated CD4-positive, alpha-beta T cell.	tmpzr1t_l9r_go_relaxed.owl	activated CD4-positive, alpha-beta T-lymphocyte apoptotic process|activated CD4-positive, alpha-beta T-cell apoptosis|activated CD4-positive, alpha-beta T-lymphocyte apoptosis|activated CD4-positive, alpha-beta T cell apoptosis|activated CD4-positive, alpha-beta T lymphocyte apoptotic process|activated CD4-positive, alpha-beta T lymphocyte apoptosis|activated CD4-positive, alpha-beta T-cell apoptotic process							pga	2016-08-25T08:13:40Z					biological_process											owl:Class	
GO:0071575	biolink:NamedThing	integral component of external side of plasma membrane	The component of the plasma membrane consisting of the gene products that penetrate only the external side of the membrane.	tmpzr1t_l9r_go_relaxed.owl	integral to external side of plasma membrane|integral to external leaflet of plasma membrane							mah	2010-01-26T05:20:28Z					cellular_component											owl:Class	
GO:0031233	biolink:NamedThing	intrinsic component of external side of plasma membrane	The component of a plasma membrane consisting of gene products and protein complexes that penetrate the external side of the plasma membrane only, either directly or via some covalently attached hydrophobic anchor.	tmpzr1t_l9r_go_relaxed.owl	intrinsic to external side of plasma membrane|intrinsic to external leaflet of plasma membrane													cellular_component											owl:Class	
GO:0031458	biolink:NamedThing	ABC-type betaine transporter activity	Catalysis of the reaction: ATP + H2O + a betaine(out) = ADP + phosphate + a betaine(in).	tmpzr1t_l9r_go_relaxed.owl	ATPase-coupled betaine transporter activity|betaine-transporting ATPase activity|ABC-type betaine transmembrane transporter activity|ATP-dependent betaine transporter activity|betaine ABC transporter													molecular_function											owl:Class	
GO:0099043	biolink:NamedThing	cargo loading involved in clathrin-dependent endocytosis	Formation of a macromolecular complex during clathrin-dependent endocytosis that connects the assembling clathrin coat to the proteins and/or lipoproteins to be transported in an endocytic vesicle. This complex includes a receptor and an adaptor protein that links the receptor to the clathrin coat.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0035652	biolink:NamedThing	clathrin-coated vesicle cargo loading	Formation of a macromolecular complex between the cytoplasmic coat proteins on clathrin-coated vesicles and proteins and/or lipoproteins that are going to be transported by a vesicle.	tmpzr1t_l9r_go_relaxed.owl	cargo loading into clathrin-coated vesicle							bf	2011-01-25T11:00:43Z					biological_process											owl:Class	
GO:0000270	biolink:NamedThing	peptidoglycan metabolic process	The chemical reactions and pathways involving peptidoglycans, any of a class of glycoconjugates found only in bacterial cell walls and consisting of strands of glycosaminoglycan cross-linked by oligopeptides to form a huge and rigid network.	tmpzr1t_l9r_go_relaxed.owl	murein metabolic process|peptidoglycan metabolism|murein metabolism											GO:0009284		biological_process											owl:Class	
GO:0086030	biolink:NamedThing	adenylate cyclase-activating adrenergic receptor signaling pathway involved in cardiac muscle relaxation	An adrenergic receptor signaling pathway that contributes to a reduction in cardiac muscle contraction. Beta-adrenergic receptor-induced cardiac relaxation is achieved by a GPCR-activated adenylate cyclase generating cAMP; cAMP then activates the cAMP-dependent protein kinase A (PKA), which phosphorylates the sarcoplasmic reticulum (SR) membrane protein PLB. In its non-phosphorylated state, PLB acts as an inhibitor of the ATPase Ca(2+) pump of the cardiac SR (SERCA2a); inhibition of the pump is relieved upon phosphorylation. The pump removes Ca(2+) from the cytoplasm, thereby preventing cytosolic Ca(2+)-dependent activation of contractile proteins, leading to enhanced muscle relaxation.	tmpzr1t_l9r_go_relaxed.owl	Gs-coupled adrenergic receptor signaling pathway involved in cardiac muscle relaxation|adrenergic receptor signaling pathway involved in cardiac muscle relaxation|adrenergic receptor-induced cardiac relaxation|adrenergic receptor signaling pathway involved in cardiac muscle relaxation via activation of AC							tb	2011-11-11T02:53:24Z					biological_process											owl:Class	
GO:0045886	biolink:NamedThing	negative regulation of synaptic assembly at neuromuscular junction	Any process that stops, prevents, or reduces the frequency, rate or extent of synaptic assembly at neuromuscular junction.	tmpzr1t_l9r_go_relaxed.owl	inhibition of synaptic growth at neuromuscular junction|negative regulation of synaptic growth at neuromuscular junction|down regulation of synaptic growth at neuromuscular junction|downregulation of synaptic growth at neuromuscular junction|down-regulation of synaptic growth at neuromuscular junction													biological_process											owl:Class	
GO:0051964	biolink:NamedThing	negative regulation of synapse assembly	Any process that stops, prevents, or reduces the frequency, rate or extent of synapse assembly, the aggregation, arrangement and bonding together of a set of components to form a synapse.	tmpzr1t_l9r_go_relaxed.owl	down regulation of synapse assembly|negative regulation of synaptogenesis|downregulation of synapse assembly|negative regulation of synapse biogenesis|down-regulation of synapse assembly|inhibition of synapse assembly													biological_process											owl:Class	
GO:0090212	biolink:NamedThing	negative regulation of establishment of blood-brain barrier	Any process that decreases the rate, frequency or extent of the establishment of the blood-brain barrier, a selectively permeable structural and functional barrier that exists between the capillaries and the brain.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of establishment of BBB							tb	2009-12-23T12:15:53Z					biological_process											owl:Class	
GO:0090210	biolink:NamedThing	regulation of establishment of blood-brain barrier	Any process that modulates the rate, frequency or extent of the establishment of the blood-brain barrier, a selectively permeable structural and functional barrier that exists between the capillaries and the brain.	tmpzr1t_l9r_go_relaxed.owl	regulation of establishment of BBB							tb	2009-12-23T12:15:53Z					biological_process											owl:Class	
GO:1905039	biolink:NamedThing	carboxylic acid transmembrane transport	The process in which carboxylic acid is transported across a membrane.	tmpzr1t_l9r_go_relaxed.owl								vw	2016-03-09T15:33:53Z					biological_process											owl:Class	
GO:0102827	biolink:NamedThing	galactosylononitol-raffinose galactosyltransferase activity	Catalysis of the reaction: raffinose + D-galactosylononitol = stachyose + 1D-4-O-methyl-myo-inositol.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-8282									molecular_function											owl:Class	
GO:0051255	biolink:NamedThing	spindle midzone assembly	The cell cycle process in which aggregation, arrangement and bonding together of a set of components to form the spindle midzone. The spindle midzone is the area in the center of the spindle where the spindle microtubules from opposite poles overlap.	tmpzr1t_l9r_go_relaxed.owl	spindle midzone formation|spindle midzone biosynthesis|spindle midzone biogenesis													biological_process											owl:Class	
GO:0015136	biolink:NamedThing	sialic acid transmembrane transporter activity	Enables the transfer of sialic acid from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0061302	biolink:NamedThing	smooth muscle cell-matrix adhesion	The binding of a smooth muscle cell to the extracellular matrix via adhesion molecules.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-09-14T11:08:00Z					biological_process											owl:Class	
GO:1905011	biolink:NamedThing	transmembrane phosphate ion transport from cytosol to vacuole	The directed movement of phosphate ions from the cytosol across the vacuolar membrane and into the vacuolar lumen.	tmpzr1t_l9r_go_relaxed.owl	vacuolar phosphate transport							tb	2016-03-03T00:34:12Z			GO:0007037		biological_process											owl:Class	
GO:2000286	biolink:NamedThing	receptor internalization involved in canonical Wnt signaling pathway	A receptor internalization process that contributes to canonical Wnt signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	receptor internalization involved in canonical Wnt receptor signalling pathway|receptor internalization involved in Wnt receptor signalling pathway through beta-catenin|receptor internalization involved in canonical Wnt-activated signaling pathway|receptor internalization involved in Wnt receptor signaling pathway through beta-catenin|receptor internalization involved in canonical Wnt receptor signaling pathway|receptor internalization involved in Wnt receptor signaling pathway via beta-catenin|receptor internalization involved in frizzled-1 receptor signaling pathway							mah	2010-12-15T12:25:40Z					biological_process											owl:Class	
GO:1904892	biolink:NamedThing	regulation of receptor signaling pathway via STAT	Any process that modulates the frequency, rate or extent of receptor signaling via STAT.	tmpzr1t_l9r_go_relaxed.owl	regulation of kinase-STAT cascade|regulation of kinase activated-STAT cascade|regulation of STAT signalling pathway							pr	2016-01-08T08:14:33Z					biological_process											owl:Class	
GO:0010500	biolink:NamedThing	transmitting tissue development	The process whose specific outcome is the progression of the transmitting tract over time, from its formation to the mature structure. The transmitting tissue is the tissue in the style of a carpel through which the pollen tube grows; it connects the stigma and the inside of ovary.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0048467	biolink:NamedThing	gynoecium development	The process whose specific outcome is the progression of the gynoecium over time, from its formation to the mature structure. The gynoecium is the collective name for the carpels of a flower.	tmpzr1t_l9r_go_relaxed.owl	pistil development													biological_process											owl:Class	
GO:2000837	biolink:NamedThing	regulation of androstenedione secretion	Any process that modulates the frequency, rate or extent of androstenedione secretion.	tmpzr1t_l9r_go_relaxed.owl	regulation of androst-4-ene-3,17-dione secretion							bf	2011-07-26T08:40:36Z					biological_process											owl:Class	
GO:1900099	biolink:NamedThing	negative regulation of plasma cell differentiation	Any process that stops, prevents or reduces the frequency, rate or extent of plasma cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	inhibition of plasma cell development|down regulation of plasma cell differentiation|down-regulation of plasma cell development|downregulation of plasma cell differentiation|negative regulation of plasma cell development|down regulation of plasma cell development|downregulation of plasma cell development|inhibition of plasma cell differentiation|down-regulation of plasma cell differentiation							bf	2012-02-15T10:46:05Z					biological_process											owl:Class	
GO:0008618	biolink:NamedThing	7-methylguanosine metabolic process	The chemical reactions and pathways involving 7-methylguanosine, a modified nucleoside that forms a cap at the 5'-terminus of eukaryotic mRNA.	tmpzr1t_l9r_go_relaxed.owl	7-methylguanosine metabolism													biological_process											owl:Class	
GO:1901068	biolink:NamedThing	guanosine-containing compound metabolic process	The chemical reactions and pathways involving guanosine-containing compounds (guanosines).	tmpzr1t_l9r_go_relaxed.owl	guanosines metabolism|guanosines metabolic process|guanosine-containing compound metabolism							bf	2012-07-02T01:51:37Z					biological_process											owl:Class	
GO:0031795	biolink:NamedThing	G protein-coupled GABA receptor binding	Binding to a G protein-coupled (metabotropic) GABA receptor.	tmpzr1t_l9r_go_relaxed.owl	GABAB receptor binding|metabotropic GABA receptor binding|metabotropic GABA receptor ligand|G-protein coupled GABA receptor binding													molecular_function											owl:Class	
GO:0050811	biolink:NamedThing	GABA receptor binding	Binding to a gamma-aminobutyric acid (GABA, 4-aminobutyrate) receptor.	tmpzr1t_l9r_go_relaxed.owl	diazepam binding inhibitor activity|4-aminobutanoate receptor binding|gamma-aminobutyric acid receptor binding|4-aminobutyrate receptor binding													molecular_function											owl:Class	
GO:0048684	biolink:NamedThing	positive regulation of collateral sprouting of intact axon in response to injury	Any process that activates, maintains or increases the rate of collateral sprouting of an intact axon as a result of injury to an axon.	tmpzr1t_l9r_go_relaxed.owl	stimulation of collateral sprouting of intact axon in response to injury|up-regulation of collateral sprouting of intact axon in response to injury|upregulation of collateral sprouting of intact axon in response to injury|activation of collateral sprouting of intact axon in response to injury|up regulation of collateral sprouting of intact axon in response to injury													biological_process											owl:Class	
GO:0062003	biolink:NamedThing	negative regulation of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity	Any process that decreases the frequency or rate of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity.	tmpzr1t_l9r_go_relaxed.owl								dph	2018-02-26T13:23:20Z					biological_process											owl:Class	
GO:0045540	biolink:NamedThing	regulation of cholesterol biosynthetic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cholesterol.	tmpzr1t_l9r_go_relaxed.owl	regulation of cholesterol biosynthesis|regulation of cholesterol formation|regulation of cholesterol anabolism|regulation of cholesterol synthesis													biological_process											owl:Class	
GO:0039645	biolink:NamedThing	modulation by virus of host G1/S transition checkpoint	Any viral process that modulates the frequency, rate or extent of the host cell G1/S transition checkpoint.	tmpzr1t_l9r_go_relaxed.owl	G1/S host cell cycle checkpoint dysregulation by virus				VZ:880			bf	2012-10-09T15:08:57Z					biological_process											owl:Class	
GO:0060153	biolink:NamedThing	modulation by virus of host cell cycle	Any viral process that modulates the rate or extent of progression through the cell cycle.	tmpzr1t_l9r_go_relaxed.owl	modulation of host cell cycle by virus|viral process regulating host cell cycle|regulation of host cell cycle by virus|regulation by virus of host cell cycle				VZ:1636									biological_process											owl:Class	
GO:0047189	biolink:NamedThing	2,3-diaminopropionate N-oxalyltransferase activity	Catalysis of the reaction: 3-amino-L-alanine + oxalyl-CoA = N(3)-oxalyl-L-2,3-diaminopropanoate + CoA.	tmpzr1t_l9r_go_relaxed.owl	oxalyldiaminopropionate synthase activity|oxalyldiaminopropionic synthase activity|ODAP synthase activity|oxalyl-CoA:L-2,3-diaminopropanoate N3-oxalyltransferase activity|oxalyl-CoA:L-2,3-diaminopropanoate 3-N-oxalyltransferase activity|oxalyl-CoA:L-alpha,beta-diaminopropionic acid oxalyltransferase activity				MetaCyc:2.3.1.58-RXN|KEGG_REACTION:R04211|EC:2.3.1.58|RHEA:13465									molecular_function											owl:Class	
GO:1904262	biolink:NamedThing	negative regulation of TORC1 signaling	Any process that stops, prevents or reduces the frequency, rate or extent of TORC1 signaling.	tmpzr1t_l9r_go_relaxed.owl	inhibition of TORC1 signaling|downregulation of TORC1 signaling|down regulation of TORC1 signal transduction|downregulation of TORC1 signal transduction|down-regulation of TORC1 signaling|down regulation of TORC1 signaling|inhibition of TORC1 signal transduction|negative regulation of TORC1 signal transduction|down-regulation of TORC1 signal transduction							lb	2015-05-27T13:13:04Z					biological_process											owl:Class	
GO:0019326	biolink:NamedThing	nitrotoluene metabolic process	The chemical reactions and pathways involving nitrotoluene, any methylbenzene molecule with NO2 group(s) attached.	tmpzr1t_l9r_go_relaxed.owl	nitrotoluene metabolism													biological_process											owl:Class	
GO:0120196	biolink:NamedThing	negative regulation of anther dehiscence	Any process that stops, prevents, or reduces the frequency, rate or extent of anther dehiscence.	tmpzr1t_l9r_go_relaxed.owl								krc	2019-04-09T22:03:16Z					biological_process											owl:Class	
GO:0019677	biolink:NamedThing	NAD catabolic process	The chemical reactions and pathways resulting in the breakdown of nicotinamide adenine dinucleotide, a coenzyme present in most living cells and derived from the B vitamin nicotinic acid; catabolism may be of either the oxidized form, NAD, or the reduced form, NADH.	tmpzr1t_l9r_go_relaxed.owl	reduced NAD catabolism|oxidized NAD catabolism|NAD catabolism|reduced nicotinamide adenine dinucleotide catabolic process|NAD degradation|NAD (reduced) catabolism|NADH catabolic process|nicotinamide adenine dinucleotide catabolism|oxidized NAD catabolic process|reduced nicotinamide adenine dinucleotide catabolism|NAD (reduced) catabolic process|oxidized nicotinamide adenine dinucleotide catabolism|NAD (oxidized) catabolic process|NAD breakdown|oxidized nicotinamide adenine dinucleotide catabolic process|reduced NAD catabolic process|nicotinamide adenine dinucleotide catabolic process|NAD (oxidized) catabolism|NADH catabolism											GO:0006737		biological_process											owl:Class	
GO:0046496	biolink:NamedThing	nicotinamide nucleotide metabolic process	The chemical reactions and pathways involving nicotinamide nucleotides, any nucleotide that contains combined nicotinamide.	tmpzr1t_l9r_go_relaxed.owl	nicotinamide nucleotide metabolism													biological_process											owl:Class	
GO:0045882	biolink:NamedThing	negative regulation of sulfur utilization	Any process that stops, prevents, or reduces the frequency, rate or extent of sulfur utilization.	tmpzr1t_l9r_go_relaxed.owl	downregulation of sulfur utilization|inhibition of sulfur utilization|negative regulation of sulphur utilization|down-regulation of sulfur utilization|down regulation of sulfur utilization													biological_process											owl:Class	
GO:0006792	biolink:NamedThing	regulation of sulfur utilization	Any process that modulates the frequency, rate or extent of sulfur utilization.	tmpzr1t_l9r_go_relaxed.owl	regulation of sulphur utilization													biological_process											owl:Class	
GO:0098621	biolink:NamedThing	phosphoseryl-selenocysteinyl-tRNA selenium transferase activity	Catalysis of the reaction: O-phosphoseryl-tRNA(Sec) + selenophosphoric acid + H2O => L-selenocysteinyl-tRNA(Sec) + 2 phosphoric acid.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-2408555|RHEA:25041|EC:2.9.1.2									molecular_function											owl:Class	
GO:0016785	biolink:NamedThing	selenotransferase activity	Catalysis of the transfer of a selenium-containing group from one compound (donor) to another (acceptor).	tmpzr1t_l9r_go_relaxed.owl	transferase activity, transferring selenium-containing groups	https://github.com/geneontology/go-ontology/issues/20486			EC:2.9.1.-							GO:0016786		molecular_function											owl:Class	
GO:0106372	biolink:NamedThing	primary fluorescent dioxobilin-type chlorophyll catabolite methylesterase activity	Catalysis of the reaction: H2O + primary fluorescent dioxobilin-type chlorophyll catabolite = H+ + methanol + O13(4)-desmethyl pFCC.	tmpzr1t_l9r_go_relaxed.owl								hjd	2021-04-01T16:53:38Z					molecular_function											owl:Class	
GO:0031270	biolink:NamedThing	pseudopodium retraction	The myosin-based contraction and retraction of a pseudopodium.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0031268	biolink:NamedThing	pseudopodium organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a pseudopodium, a temporary protrusion or retractile process of a cell, associated with cellular movement.	tmpzr1t_l9r_go_relaxed.owl	pseudopodium organization and biogenesis|pseudopodium organisation													biological_process											owl:Class	
GO:0016612	biolink:NamedThing	molybdenum-iron nitrogenase complex	An enzyme complex containing a molybdenum-iron cluster found in many species. It is composed of two proteins, dinitrogenase and nitrogenase reductase; dinitrogenase, the molybdenum-iron protein, is tetrameric with an alpha2-beta2 structure, and nitrogenase reductase is a homodimer.	tmpzr1t_l9r_go_relaxed.owl	molybdenum-iron nitrogenase activity													cellular_component											owl:Class	
GO:1905037	biolink:NamedThing	autophagosome organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an autophagosome.	tmpzr1t_l9r_go_relaxed.owl	autophagic vacuole organization|initial autophagic vacuole organization							bf	2016-03-08T14:18:10Z					biological_process											owl:Class	
GO:0006693	biolink:NamedThing	prostaglandin metabolic process	The chemical reactions and pathways involving prostaglandins, any of a group of biologically active metabolites which contain a cyclopentane ring due to the formation of a bond between two carbons of a fatty acid. They have a wide range of biological activities.	tmpzr1t_l9r_go_relaxed.owl	prostaglandin metabolism													biological_process											owl:Class	
GO:0006692	biolink:NamedThing	prostanoid metabolic process	The chemical reactions and pathways involving prostanoids, any compound based on or derived from the prostanoate structure.	tmpzr1t_l9r_go_relaxed.owl	prostanoid metabolism													biological_process											owl:Class	
GO:0015851	biolink:NamedThing	nucleobase transport	The directed movement of a nucleobase, any nitrogenous base that is a constituent of a nucleoside, nucleotide, or nucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	nucleobase transmembrane transport													biological_process											owl:Class	
GO:0031510	biolink:NamedThing	SUMO activating enzyme complex	A conserved heterodimeric complex with SUMO activating enzyme activity.	tmpzr1t_l9r_go_relaxed.owl	SAE|SUMO E1 activator enzyme complex													cellular_component											owl:Class	
GO:0018054	biolink:NamedThing	peptidyl-lysine biotinylation	The covalent modification of peptidyl-lysine by biotin to form peptidyl-N6-biotinyl-L-lysine.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0117									biological_process											owl:Class	
GO:0010669	biolink:NamedThing	epithelial structure maintenance	A tissue homeostatic process required for the maintenance of epithelial structure.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1904086	biolink:NamedThing	regulation of epiboly involved in gastrulation with mouth forming second	Any process that modulates the frequency, rate or extent of epiboly involved in gastrulation with mouth forming second.	tmpzr1t_l9r_go_relaxed.owl								dos	2015-03-25T11:17:34Z					biological_process											owl:Class	
GO:2000420	biolink:NamedThing	negative regulation of eosinophil extravasation	Any process that stops, prevents or reduces the frequency, rate or extent of eosinophil extravasation.	tmpzr1t_l9r_go_relaxed.owl								mah	2011-02-23T01:47:18Z					biological_process											owl:Class	
GO:0034038	biolink:NamedThing	deoxyhypusine synthase activity	Catalysis of the reaction: [eIF5A-precursor]-lysine + spermidine = [eIF5A-precursor]-deoxyhypusine + propane-1,3-diamine. Four sub-reactions have been identified,in which the intermediates remain tightly associated with the enzyme: spermidine + NAD+ = dehydrospermidine + NADH; dehydrospermidine + [enzyme]-lysine = N-(4-aminobutylidene)-[enzyme]-lysine + propane-1,3-diamine; N-(4-aminobutylidene)-[enzyme]-lysine + [eIF5A-precursor]-lysine = N-(4-aminobutylidene)-[eIF5A-precursor]-lysine + [enzyme]-lysine; N-(4-aminobutylidene)-[eIF5A-precursor]-lysine + NADH + H+ = [eIF5A-precursor]-deoxyhypusine + NAD+.	tmpzr1t_l9r_go_relaxed.owl	spermidine:eIF5A-lysine 4-aminobutyltransferase (propane-1,3-diamine-forming) activity|eIF-5A-deoxyhypusine synthase activity|eIF5A-precursor-lysine:spermidine 4-aminobutyltransferase (propane-1,3-diamine-forming) activity				Reactome:R-HSA-204617|EC:2.5.1.46|RHEA:33299|MetaCyc:2.5.1.46-RXN|Reactome:R-HSA-204647	Note that this term is equivalent to the obsolete molecular function term 'deoxyhypusine synthase activity ; GO:0004171' and corresponds closely to the biological process term 'deoxyhypusine biosynthetic process from spermidine, using deoxyhypusine synthase ; GO:0050983'.								molecular_function											owl:Class	
GO:0106026	biolink:NamedThing	Gly-tRNA(Ala) hydrolase activity	Catalysis of the hydrolysis of misacylated Gly-tRNA(Ala).	tmpzr1t_l9r_go_relaxed.owl								hjd	2017-06-16T17:13:33Z					molecular_function											owl:Class	
GO:1900207	biolink:NamedThing	negative regulation of pronephric nephron tubule development	Any process that stops, prevents or reduces the frequency, rate or extent of pronephric nephron tubule development.	tmpzr1t_l9r_go_relaxed.owl	down regulation of pronephric nephron tubule development|down-regulation of pronephric nephron tubule development|inhibition of pronephric nephron tubule development|downregulation of pronephric nephron tubule development							bf	2012-03-22T09:23:23Z					biological_process											owl:Class	
GO:1905097	biolink:NamedThing	regulation of guanyl-nucleotide exchange factor activity	Any process that modulates the frequency, rate or extent of guanyl-nucleotide exchange factor activity.	tmpzr1t_l9r_go_relaxed.owl	regulation of GDS|regulation of guanyl-nucleotide release factor activity|regulation of GNRP|regulation of GEF|regulation of guanyl-nucleotide releasing factor|regulation of GDP-dissociation stimulator activity	https://github.com/geneontology/go-ontology/issues/18750						sl	2016-03-31T16:09:35Z					biological_process											owl:Class	
GO:0043087	biolink:NamedThing	regulation of GTPase activity	Any process that modulates the rate of GTP hydrolysis by a GTPase.	tmpzr1t_l9r_go_relaxed.owl	regulation of Rap GTPase activity|regulation of Rac GTPase activity|regulation of Ras GTPase activity|regulation of Ral GTPase activity|regulation of Rab GTPase activity|regulation of Rho GTPase activity|regulation of ARF GTPase activity|regulation of Ran GTPase activity|regulation of Cdc42 GTPase activity											GO:0032313|GO:0032314|GO:0032317|GO:0032319|GO:0043088|GO:0032318|GO:0032315|GO:0032312|GO:0032316		biological_process											owl:Class	
GO:0072094	biolink:NamedThing	metanephric renal vesicle induction	Signaling at short range between cells of the ureteric bud terminus and the kidney mesenchyme that positively regulates the formation of the metanephric renal vesicle.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of metanephros formation							mah	2010-02-10T01:23:20Z					biological_process											owl:Class	
GO:0072216	biolink:NamedThing	positive regulation of metanephros development	Any process that increases the rate, frequency or extent of metanephros development. Metanephros development is the process whose specific outcome is the progression of the metanephros over time, from its formation to the mature structure. The metanephros is an organ that filters the blood and excretes the end products of body metabolism in the form of urine.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-03-18T01:40:12Z					biological_process											owl:Class	
GO:0005250	biolink:NamedThing	A-type (transient outward) potassium channel activity	Enables the transmembrane transfer of a potassium ion by an outwardly-rectifying voltage-gated channel that produces a transient outward current upon a step change in membrane potential.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-5577234									molecular_function											owl:Class	
GO:0032753	biolink:NamedThing	positive regulation of interleukin-4 production	Any process that activates or increases the frequency, rate, or extent of interleukin-4 production.	tmpzr1t_l9r_go_relaxed.owl	upregulation of interleukin-4 production|activation of interleukin-4 production|positive regulation of interleukin-4 secretion|up-regulation of interleukin-4 production|positive regulation of IL-4 production|stimulation of interleukin-4 production|positive regulation of interleukin-4 biosynthetic process|up regulation of interleukin-4 production											GO:0045404|GO:0150135		biological_process											owl:Class	
GO:1990906	biolink:NamedThing	accessory outer segment	A cilium-like cell projection emanating from the inner segment and running alongside the outer segment of photoreceptors.	tmpzr1t_l9r_go_relaxed.owl								dph	2015-11-24T13:56:06Z					cellular_component											owl:Class	
GO:0031468	biolink:NamedThing	nuclear membrane reassembly	The reformation of the nuclear membranes following their breakdown in the context of a normal process.	tmpzr1t_l9r_go_relaxed.owl	nuclear envelope reassembly	https://github.com/geneontology/go-ontology/issues/20636												biological_process											owl:Class	
GO:0061864	biolink:NamedThing	basement membrane constituent secretion	The controlled release of molecules that form the basement membrane, including carbohydrates and glycoproteins by a cell.	tmpzr1t_l9r_go_relaxed.owl								dph	2017-04-07T18:23:39Z					biological_process											owl:Class	
GO:0070278	biolink:NamedThing	extracellular matrix constituent secretion	The controlled release of molecules that form the extracellular matrix, including carbohydrates and glycoproteins by a cell.	tmpzr1t_l9r_go_relaxed.owl	ECM secretion|ECM constituent secretion													biological_process											owl:Class	
GO:0043903	biolink:NamedThing	regulation of biological process involved in symbiotic interaction	Any process that modulates the frequency, rate or extent of symbiosis, an interaction between two organisms living together in more or less intimate association.	tmpzr1t_l9r_go_relaxed.owl	regulation of symbiosis, encompassing mutualism through parasitism|regulation of symbiotic process|regulation of interspecies interactions between organisms	https://github.com/geneontology/go-ontology/issues/19028|https://github.com/geneontology/go-ontology/issues/20191				regulation of interspecies interactions between organisms								biological_process											owl:Class	
GO:1905746	biolink:NamedThing	positive regulation of mRNA cis splicing, via spliceosome	Any process that activates or increases the frequency, rate or extent of mRNA cis splicing, via spliceosome.	tmpzr1t_l9r_go_relaxed.owl								vw	2016-12-07T14:01:52Z					biological_process											owl:Class	
GO:0042395	biolink:NamedThing	ecdysis, collagen and cuticulin-based cuticle	The shedding of the old collagen and cuticulin-based cuticle fragments during the molting cycle. Examples of this process are found in invertebrates.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0022404	biolink:NamedThing	molting cycle process	A multicellular organismal process involved in the periodic casting off and regeneration of an outer covering of cuticle, feathers, hair, horns, skin.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0061101	biolink:NamedThing	neuroendocrine cell differentiation	The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a neuroendocrine cell. A neuroendocrine cell is a cell that receives input form a neuron which controls the secretion of an endocrine substance.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-04-28T09:42:20Z					biological_process											owl:Class	
GO:0060563	biolink:NamedThing	neuroepithelial cell differentiation	The process in which epiblast cells acquire specialized features of neuroepithelial cells.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-04-29T01:50:05Z					biological_process											owl:Class	
GO:0070159	biolink:NamedThing	mitochondrial threonyl-tRNA aminoacylation	The process of coupling threonine to threonyl-tRNA in a mitochondrion, catalyzed by threonyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0006435	biolink:NamedThing	threonyl-tRNA aminoacylation	The process of coupling threonine to threonyl-tRNA, catalyzed by threonyl-tRNA synthetase. The threonyl-tRNA synthetase is a  class-II synthetase. The activated amino acid is transferred to the 3'-OH group of a threonine-accetping tRNA.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0061366	biolink:NamedThing	behavioral response to chemical pain	Any process that results in a change in the behaviour of an organism as a result of a chemical pain stimulus.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-10-21T03:25:01Z					biological_process											owl:Class	
GO:0035517	biolink:NamedThing	PR-DUB complex	A multimeric protein complex that removes monoubiquitin from histone H2A. In Drosophila and mammals, the core of the complex is composed of Calypso/BAP1 and Asx/ASXL1, respectively.	tmpzr1t_l9r_go_relaxed.owl	Polycomb repressive deubiquitinase complex							bf	2010-05-04T04:19:02Z					cellular_component											owl:Class	
GO:1900179	biolink:NamedThing	positive regulation of aflatoxin biosynthetic process	Any process that activates or increases the frequency, rate or extent of aflatoxin biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	upregulation of aflatoxin synthesis|upregulation of aflatoxin biosynthetic process|upregulation of aflatoxin biosynthesis|up-regulation of aflatoxin synthesis|up-regulation of aflatoxin biosynthetic process|upregulation of aflatoxin formation|positive regulation of aflatoxin biosynthesis|positive regulation of aflatoxin synthesis|positive regulation of aflatoxin anabolism|up regulation of aflatoxin formation|activation of aflatoxin biosynthesis|up-regulation of aflatoxin biosynthesis|up-regulation of aflatoxin anabolism|up regulation of aflatoxin synthesis|up regulation of aflatoxin biosynthesis|up regulation of aflatoxin anabolism|upregulation of aflatoxin anabolism|up-regulation of aflatoxin formation|activation of aflatoxin biosynthetic process|activation of aflatoxin formation|up regulation of aflatoxin biosynthetic process|activation of aflatoxin synthesis|activation of aflatoxin anabolism|positive regulation of aflatoxin formation							di	2012-03-09T11:23:46Z					biological_process											owl:Class	
GO:1901955	biolink:NamedThing	negative regulation of retrograde dense core granule transport	Any process that stops, prevents or reduces the frequency, rate or extent of retrograde dense core granule transport.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of retrograde dense core granule transport|inhibition of retrograde dense core granule transport|downregulation of retrograde dense core granule transport|down regulation of retrograde dense core granule transport							pr	2013-02-19T13:36:47Z					biological_process											owl:Class	
GO:0060804	biolink:NamedThing	positive regulation of Wnt signaling pathway by BMP signaling pathway	A series of molecular signals generated as a consequence of any member of the BMP (bone morphogenetic protein) family binding to a cell surface receptor that results in an increase in the rate, frequency or extent of a Wnt signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of WNT receptor signalling pathway by BMP signalling pathway|positive regulation of WNT receptor signaling pathway by BMP signaling pathway|positive regulation of Wnt-activated signaling pathway by BMP signaling pathway							dph	2009-08-06T01:52:48Z					biological_process											owl:Class	
GO:0030177	biolink:NamedThing	positive regulation of Wnt signaling pathway	Any process that activates or increases the frequency, rate or extent of Wnt signal transduction.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of frizzled signaling pathway|positive regulation of Wnt-activated signaling pathway|up regulation of frizzled signaling pathway|stimulation of Wnt receptor signaling pathway|activation of frizzled signaling pathway|positive regulation of frizzled signalling pathway|positive regulation of frizzled signaling pathway|up regulation of Wnt receptor signaling pathway|positive regulation of Wnt receptor signalling pathway|positive regulation of Wnt receptor signaling pathway|upregulation of frizzled signaling pathway|stimulation of frizzled signaling pathway|up-regulation of Wnt receptor signaling pathway|activation of Wnt receptor signaling pathway|upregulation of Wnt receptor signaling pathway											GO:0045811		biological_process											owl:Class	
GO:2000470	biolink:NamedThing	positive regulation of peroxidase activity	Any process that activates or increases the frequency, rate or extent of peroxidase activity.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of peroxidase reaction|positive regulation of donor:hydrogen-peroxide oxidoreductase activity|positive regulation of oxyperoxidase activity							bf	2011-03-08T02:19:25Z					biological_process											owl:Class	
GO:0051266	biolink:NamedThing	sirohydrochlorin ferrochelatase activity	Catalysis of the reaction: siroheme + 2 H+ = Fe(2+) + sirohydrochlorin.	tmpzr1t_l9r_go_relaxed.owl	Met8P|siroheme ferro-lyase (sirohydrochlorin-forming)|SirB|CysG|sirohydrochlorin ferro-lyase activity|siroheme synthase activity				MetaCyc:SIROHEME-FERROCHELAT-RXN|RHEA:24360|EC:4.99.1.4|KEGG_REACTION:R02864									molecular_function											owl:Class	
GO:0036031	biolink:NamedThing	recruitment of mRNA capping enzyme to RNA polymerase II holoenzyme complex	The process in which the guanylyltransferase enzyme responsible for adding a 7-methylguanosine cap on pre-mRNA becomes associated with the RNA polymerase II holoenzyme complex and the 5' end of a transcript.	tmpzr1t_l9r_go_relaxed.owl	recruitment of guanylyltransferase to RNA polymerase II holoenzyme complex|capping enzyme targeting to RNA polymerase II							bf	2011-10-24T10:56:46Z					biological_process											owl:Class	
GO:0003707	biolink:NamedThing	steroid hormone receptor activity	Combining with a steroid hormone and transmitting the signal within the cell to initiate a change in cell activity or function.	tmpzr1t_l9r_go_relaxed.owl						Some steroid hormone receptors reside in the plasma membrane and signal through second messengers or other intracellular signal transduction pathways. For steroid hormone receptors that act in the nucleus to regulate transcription, consider also annotating to the terms: nuclear receptor activity ; GO:0004879' or nuclear receptor transcription coactivator activity ; GO:0030374'.								molecular_function											owl:Class	
GO:0035254	biolink:NamedThing	glutamate receptor binding	Binding to a glutamate receptor.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0006203	biolink:NamedThing	dGTP catabolic process	The chemical reactions and pathways resulting in the breakdown of dGTP, guanosine triphosphate.	tmpzr1t_l9r_go_relaxed.owl	dGTP breakdown|dGTP catabolism|dGTP degradation													biological_process											owl:Class	
GO:0075012	biolink:NamedThing	negative regulation of germ tube formation	Any process that stops, prevents, or reduces the frequency, rate or extent of germ tube formation on or near host. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of germ tube formation on or near host													biological_process											owl:Class	
GO:2000280	biolink:NamedThing	regulation of root development	Any process that modulates the frequency, rate or extent of root development.	tmpzr1t_l9r_go_relaxed.owl								dhl	2010-12-08T09:30:21Z					biological_process											owl:Class	
GO:0033493	biolink:NamedThing	esculetin biosynthetic process	The chemical reactions and pathways resulting in the formation of esculetin, 6,7-dihydroxycoumarin.	tmpzr1t_l9r_go_relaxed.owl	esculetin anabolism|esculetin synthesis|esculetin formation|esculetin biosynthesis				MetaCyc:PWY-5349									biological_process											owl:Class	
GO:0009805	biolink:NamedThing	coumarin biosynthetic process	The chemical reactions and pathways resulting in the formation of coumarins, a class of compounds derived from the phenylacrylic skeleton of cinnamic acids.	tmpzr1t_l9r_go_relaxed.owl	coumarin formation|coumarin synthesis|coumarin biosynthesis|coumarin anabolism				MetaCyc:PWY-5176									biological_process											owl:Class	
GO:0047563	biolink:NamedThing	3-hydroxybenzoate 2-monooxygenase activity	Catalysis of the reaction: 3-hydroxybenzoate + AH(2) + O(2) = 2,3-dihydroxybenzoate + A + H(2)O.	tmpzr1t_l9r_go_relaxed.owl	3-HBA-2-hydroxylase activity|3-hydroxybenzoate 2-hydroxylase activity|3-hydroxybenzoate,hydrogen-donor:oxygen oxidoreductase (2-hydroxylating)				KEGG_REACTION:R01508|RHEA:14193|EC:1.14.99.23|MetaCyc:3-HYDROXYBENZOATE-2-MONOOXYGENASE-RXN									molecular_function											owl:Class	
GO:0031632	biolink:NamedThing	positive regulation of synaptic vesicle fusion to presynaptic active zone membrane	Any process that activates or increases the frequency, rate or extent of synaptic vesicle fusion to the presynaptic membrane.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of synaptic vesicle fusion to presynaptic active zone membrane|activation of synaptic vesicle fusion to presynaptic membrane|negative regulation of synaptic vesicle fusion to presynaptic membrane|up regulation of synaptic vesicle fusion to presynaptic active zone membrane|up regulation of synaptic vesicle fusion to presynaptic membrane|positive regulation of synaptic vesicle fusion to pre-synaptic membrane|up-regulation of synaptic vesicle fusion to presynaptic membrane|upregulation of synaptic vesicle fusion to presynaptic membrane|stimulation of synaptic vesicle fusion to presynaptic membrane													biological_process											owl:Class	
GO:1902086	biolink:NamedThing	fumagillin biosynthetic process	The chemical reactions and pathways resulting in the formation of fumagillin.	tmpzr1t_l9r_go_relaxed.owl	fumagillin biosynthesis|fumagillin formation|fumagillin anabolism|fumagillin synthesis							di	2013-04-25T14:00:50Z					biological_process											owl:Class	
GO:0033881	biolink:NamedThing	bile-acid-CoA hydrolase activity	Catalysis of the reaction: deoxycholoyl-CoA + H(2)O = CoA + deoxycholate + H(+).	tmpzr1t_l9r_go_relaxed.owl	deoxycholoyl-CoA hydrolase activity|bile acid-coenzyme A hydrolase activity				RHEA:17693|EC:3.1.2.26|MetaCyc:BACOAHYDRO-RXN|KEGG_REACTION:R07295									molecular_function											owl:Class	
GO:0016289	biolink:NamedThing	CoA hydrolase activity	Catalysis of the reaction: X-CoA + H2O = X + CoA; X may be any group.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-193385									molecular_function											owl:Class	
GO:0038101	biolink:NamedThing	sequestering of nodal from receptor via nodal binding	Binding to a nodal protein in the extracellular region, and inhibiting nodal signaling by preventing nodal from binding to its cell surface receptor.	tmpzr1t_l9r_go_relaxed.owl	extracellular regulation of nodal|binding to and sequestering nodal|nodal antagonist activity							bf	2012-02-17T11:21:22Z					biological_process											owl:Class	
GO:0039600	biolink:NamedThing	induction by virus of host endonucleolytic cleavage-dependent mRNA catabolic process	The process in which a virus increases the frequency, rate or extent of the breakdown of host nuclear-transcribed mRNAs that begins with endonucleolytic cleavage (by either a host or a viral RNAse) to generate unprotected ends.	tmpzr1t_l9r_go_relaxed.owl	induction by virus of host nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay|induction by virus of host endonucleolytic cleavage-dependent mRNA decay					Some viruses utilize a host RNase to induce endonucleolytic cleavage of template mRNAs (e.g. the NSP1 protein of SARS coronavirus); for these consider instead annotating to the child term 'induction by virus of host endoribonuclease activity ; GO:0039597'. Other viral proteins act as endonucleases themselves to cleave mRNA and then rely on the host degradation machinery to clear the resulting fragments (e.g. gamma herpesvirus SOX protein); for these cases consider instead annotating to the child term 'endoribonuclease activity involved in viral induction of host mRNA catabolic process ; GO:0039594'.		bf	2012-07-04T05:23:43Z					biological_process											owl:Class	
GO:0097676	biolink:NamedThing	histone H3-K36 dimethylation	The modification of histone H3 by addition of two methyl groups to lysine at position 36 of the histone.	tmpzr1t_l9r_go_relaxed.owl								pr	2014-11-04T10:38:05Z					biological_process											owl:Class	
GO:0009861	biolink:NamedThing	jasmonic acid and ethylene-dependent systemic resistance	The jasmonic acid and ethylene (ethene) dependent process that confers broad spectrum systemic resistance to disease in response to wounding or a pathogen.	tmpzr1t_l9r_go_relaxed.owl	jasmonic acid/ethylene-dependent systemic resistance|jasmonic acid and ethene-dependent systemic resistance													biological_process											owl:Class	
GO:0007162	biolink:NamedThing	negative regulation of cell adhesion	Any process that stops, prevents, or reduces the frequency, rate or extent of cell adhesion.	tmpzr1t_l9r_go_relaxed.owl	cell adhesion receptor inhibitor activity|down-regulation of cell adhesion|inhibition of cell adhesion|down regulation of cell adhesion|downregulation of cell adhesion													biological_process											owl:Class	
GO:0015530	biolink:NamedThing	shikimate transmembrane transporter activity	Enables the transfer of shikimate from one side of a membrane to the other. Shikimate is an important intermediate in the biosynthesis of aromatic amino acids.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0071286	biolink:NamedThing	cellular response to magnesium ion	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a magnesium ion stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-12-10T04:05:50Z					biological_process											owl:Class	
GO:0032026	biolink:NamedThing	response to magnesium ion	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a magnesium ion stimulus.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0090641	biolink:NamedThing	microsporidian-type endospore	The middle layer in a microsporidian spore wall that lies under the exospore and outside the plasma membrane, containing chitin and proteins.	tmpzr1t_l9r_go_relaxed.owl						Microsporidian biology uses the term endospore differently than GO:0043593 endospore coat which is for a spore formed inside of another cell. Microsporidian endospore refers to the inner layer of the spore wall itself.		tb	2015-05-04T14:17:06Z					cellular_component											owl:Class	
GO:1901848	biolink:NamedThing	nicotinate catabolic process	The chemical reactions and pathways resulting in the breakdown of nicotinate.	tmpzr1t_l9r_go_relaxed.owl	nicotinate catabolism|nicotinate breakdown|nicotinate degradation							yaf	2013-01-28T11:23:52Z					biological_process											owl:Class	
GO:0046893	biolink:NamedThing	iron incorporation into hydrogenase diiron subcluster via L-cysteine ligation	The incorporation of iron into an L-cysteinyl diiron subcluster, found in Fe-hydrogenase.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0334									biological_process											owl:Class	
GO:0006667	biolink:NamedThing	sphinganine metabolic process	The chemical reactions and pathways involving sphinganine, D-erythro-2-amino-1,3-octadecanediol.	tmpzr1t_l9r_go_relaxed.owl	dihydrosphingosine metabolic process|sphinganine metabolism|dihydrosphingosine metabolism													biological_process											owl:Class	
GO:0034311	biolink:NamedThing	diol metabolic process	The chemical reactions and pathways involving a diol, a compound that contains two hydroxy groups, generally assumed to be, but not necessarily, alcoholic.	tmpzr1t_l9r_go_relaxed.owl	dihydric alcohol metabolic process|diol metabolism													biological_process											owl:Class	
GO:0018004	biolink:NamedThing	N-terminal protein formylation	The formylation of the N-terminal amino acid of proteins.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0007249	biolink:NamedThing	I-kappaB kinase/NF-kappaB signaling	The process in which a signal is passed on to downstream components within the cell through the I-kappaB-kinase (IKK)-dependent activation of NF-kappaB. The cascade begins with activation of a trimeric IKK complex (consisting of catalytic kinase subunits IKKalpha and/or IKKbeta, and the regulatory scaffold protein NEMO) and ends with the regulation of transcription of target genes by NF-kappaB. In a resting state, NF-kappaB dimers are bound to I-kappaB proteins, sequestering NF-kappaB in the cytoplasm. Phosphorylation of I-kappaB targets I-kappaB for ubiquitination and proteasomal degradation, thus releasing the NF-kappaB dimers, which can translocate to the nucleus to bind DNA and regulate transcription.	tmpzr1t_l9r_go_relaxed.owl	NF-kappaB cascade|activation of the inhibitor of kappa kinase|I-kappaB kinase/NF-kappaB cascade|I-kappaB kinase/NF-kappaB signal transduction|p50-dependent NF-kappaB signaling|canonical NF-kappaB signaling cascade													biological_process											owl:Class	
GO:0016973	biolink:NamedThing	poly(A)+ mRNA export from nucleus	The directed movement of poly(A)+ mRNA out of the nucleus into the cytoplasm.	tmpzr1t_l9r_go_relaxed.owl	poly(A)+ mRNA transport from nucleus to cytoplasm|poly(A) mRNA export from nucleus|poly(A)+ mRNA export out of nucleus|poly(A)+ mRNA export from cell nucleus|poly(A)+ mRNA-nucleus export|polyadenylated mRNA export from nucleus													biological_process											owl:Class	
GO:0010417	biolink:NamedThing	glucuronoxylan biosynthetic process	The chemical reactions and pathways resulting in the formation of glucuronoxylan, a polymer containing a beta-1,4-linked D-xylose backbone substituted with glucuronic acid residues.	tmpzr1t_l9r_go_relaxed.owl	glucuronoxylan biosynthesis|glucuronoxylan formation|glucuronoxylan synthesis|glucuronoxylan anabolism													biological_process											owl:Class	
GO:0010413	biolink:NamedThing	glucuronoxylan metabolic process	The chemical reactions and pathways involving xylan, a polymer containing a beta-(1->4)-linked D-xylose backbone decorated with glucuronic acid side units.	tmpzr1t_l9r_go_relaxed.owl	glucuronoxylan metabolism													biological_process											owl:Class	
GO:0097725	biolink:NamedThing	histone H3-K79 dimethylation	The modification of histone H3 by addition of two methyl groups to lysine at position 79 of the histone.	tmpzr1t_l9r_go_relaxed.owl	histone H3 K79 dimethylation|histone lysine H3 K79 dimethylation							pr	2016-09-15T12:41:13Z					biological_process											owl:Class	
GO:0072291	biolink:NamedThing	epithelial cell migration involved in metanephric distal tubule morphogenesis	The orderly movement of epithelial cells within a renal tubule that contributes to metanephric distal tubule morphogenesis.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-04-09T03:53:37Z					biological_process											owl:Class	
GO:0060656	biolink:NamedThing	regulation of branching involved in mammary cord morphogenesis by fat precursor cell-epithelial cell signaling	Any process that modulates the rate, frequency, or extent of branching of the mammary gland cord as a result of a signal being created by a mammary fat precursor cell and its subsequent reception and interpretation by a mammary cord epithelial cell.	tmpzr1t_l9r_go_relaxed.owl	regulation of branching involved in mammary cord morphogenesis by fat precursor cell-epithelial cell signalling							dph	2009-05-29T09:34:31Z					biological_process											owl:Class	
GO:0031131	biolink:NamedThing	reception of an inductive signal	The process in which one cell or group of cells receives, transduces, and responds to a signal generated by another cell or group of cells of different ancestry and developmental potential, such that the recipient cell(s) undergo a developmental change.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0055013	biolink:NamedThing	cardiac muscle cell development	The process whose specific outcome is the progression of a cardiac muscle cell over time, from its formation to the mature state.	tmpzr1t_l9r_go_relaxed.owl	cardiomyocyte cell development|cardiac muscle fibre development|cardiac muscle fiber development|heart muscle fiber development|heart muscle cell development											GO:0048739		biological_process											owl:Class	
GO:0150057	biolink:NamedThing	amylin receptor complex 2	A G protein-coupled receptor complex that serves as a receptor for amylin polypeptide (AMY) and consists of a calcitonin receptor (CTR/CALCR) and a receptor activity-modifying protein (RAMP) 2. Amylin receptor complex 2 (AMY2) also serves as a receptor for adrenomedullin (AM/ADM).	tmpzr1t_l9r_go_relaxed.owl	AMY2 complex							bc	2018-06-21T10:51:35Z					cellular_component											owl:Class	
GO:1903440	biolink:NamedThing	amylin receptor complex	A protein complex which is capable of amylin receptor activity.	tmpzr1t_l9r_go_relaxed.owl								pr	2014-09-16T13:25:20Z					cellular_component											owl:Class	
GO:0060110	biolink:NamedThing	basal layer of collagen and cuticulin-based cuticle extracellular matrix	The layer of cuticle most closely apposed to the hypodermal cells. The morphology of the basal layer varies with life stage. In adult C. elegans animals, the basal layers is comprised of three sublayers: two fibrous layers whose fibers run in clockwise and counter-clockwise directions meeting one another at a 60 degree angle, and an amorphous basal layer that lies underneath the fibrous layers and directly contacts the hypodermis. In C. elegans dauer and L1 larval stage animals, the basal layer is characterized by a striated pattern that appears to derive from interwoven laminae. An example of this component is found in Caenorhabditis elegans.	tmpzr1t_l9r_go_relaxed.owl	basal layer of collagen and cuticulin-based exoskeleton extracellular matrix													cellular_component											owl:Class	
GO:0036194	biolink:NamedThing	muscle cell projection	A prolongation or process extending from a muscle cell. A muscle cell is a mature contractile cell, commonly known as a myocyte. This cell has as part of its cytoplasm myofibrils organized in various patterns.	tmpzr1t_l9r_go_relaxed.owl	muscle arm|myocyte projection|myopodia							bf	2012-04-20T10:20:47Z					cellular_component											owl:Class	
GO:0106116	biolink:NamedThing	positive regulation of mitotic cohesin dsDNA (leading strand) loading	Any process that activates or increases the frequency, rate or extent of mitotic cohesin dsDNA (leading strand) loading.	tmpzr1t_l9r_go_relaxed.owl								hjd	2018-04-18T14:52:21Z					biological_process											owl:Class	
GO:1904932	biolink:NamedThing	negative regulation of cartilage condensation	Any process that stops, prevents or reduces the frequency, rate or extent of cartilage condensation.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of cartilage condensation|down regulation of cartilage condensation|downregulation of cartilage condensation|inhibition of cartilage condensation							mr	2016-01-29T18:13:39Z					biological_process											owl:Class	
GO:0070367	biolink:NamedThing	negative regulation of hepatocyte differentiation	Any process that stops or decreases the rate or extent of hepatocyte differentiation.	tmpzr1t_l9r_go_relaxed.owl	inhibition of hepatocyte differentiation|down regulation of hepatocyte differentiation|negative regulation of liver cell differentiation|down-regulation of hepatocyte differentiation|downregulation of hepatocyte differentiation													biological_process											owl:Class	
GO:0042160	biolink:NamedThing	lipoprotein modification	The chemical reactions and pathways resulting in the covalent alteration of one or more amino acid or lipid residues occurring in a lipoprotein, any conjugated, water-soluble protein in which the nonprotein group consists of a lipid or lipids.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0032402	biolink:NamedThing	melanosome transport	The directed movement of melanosomes into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0032401	biolink:NamedThing	establishment of melanosome localization	The directed movement of a melanosome to a specific location.	tmpzr1t_l9r_go_relaxed.owl	establishment of melanosome localisation													biological_process											owl:Class	
GO:0034001	biolink:NamedThing	chondroitin-sulfate-ABC exolyase activity	Catalysis of the exolytic cleavage of disaccharide residues from the non-reducing ends of both polymeric chondroitin sulfates and their oligosaccharide fragments.	tmpzr1t_l9r_go_relaxed.owl	chondroitin sulfate ABC exoeliminase activity|chondroitin sulfate ABC exolyase activity|chondroitinase activity|chondroitinase ABC activity|chondroitin sulfate ABC lyase activity|ChS ABC lyase II activity|chondroitin ABC eliminase activity|ChS ABC lyase activity				MetaCyc:4.2.2.21-RXN|EC:4.2.2.21									molecular_function											owl:Class	
GO:0047486	biolink:NamedThing	chondroitin ABC lyase activity	Catalysis of the eliminative degradation of polysaccharides containing 1,4-beta-D-hexosaminyl and 1,3-beta-D-glucuronosyl or 1,3-alpha-L-iduronosyl linkages to disaccharides containing 4-deoxy-beta-D-gluc-4-enuronosyl groups.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0043372	biolink:NamedThing	positive regulation of CD4-positive, alpha-beta T cell differentiation	Any process that activates or increases the frequency, rate or extent of CD4-positive, alpha-beta T cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	up regulation of CD4-positive, alpha beta T cell differentiation|up-regulation of CD4-positive, alpha beta T cell differentiation|positive regulation of CD4-positive, alpha beta T cell differentiation|stimulation of CD4-positive, alpha beta T cell differentiation|positive regulation of CD4-positive, alpha beta T-lymphocyte differentiation|upregulation of CD4-positive, alpha beta T cell differentiation|positive regulation of CD4-positive, alpha beta T cell development|positive regulation of CD4-positive T-lymphocyte differentiation|positive regulation of CD4-positive T lymphocyte differentiation|positive regulation of CD4-positive, alpha beta T lymphocyte differentiation|positive regulation of CD4-positive, alpha beta T-cell differentiation|activation of CD4-positive, alpha beta T cell differentiation|positive regulation of CD4-positive T-cell differentiation					Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.								biological_process											owl:Class	
GO:0050374	biolink:NamedThing	UDP-galacturonate decarboxylase activity	Catalysis of the reaction: H(+) + UDP-alpha-D-galacturonate = CO(2) + UDP-L-arabinose.	tmpzr1t_l9r_go_relaxed.owl	UDP-galacturonic acid decarboxylase activity|UDPGalUA carboxy lyase activity|UDPgalacturonate decarboxylase activity|UDP-D-galacturonate carboxy-lyase activity|UDP-D-galacturonate carboxy-lyase (UDP-L-arabinose-forming)				EC:4.1.1.67|KEGG_REACTION:R02636|MetaCyc:UDP-GALACTURONATE-DECARBOXYLASE-RXN|RHEA:19725									molecular_function											owl:Class	
GO:0002651	biolink:NamedThing	positive regulation of tolerance induction to self antigen	Any process that activates or increases the frequency, rate, or extent of tolerance induction to self antigen.	tmpzr1t_l9r_go_relaxed.owl	activation of tolerance induction to self antigen|up regulation of tolerance induction to self antigen|stimulation of tolerance induction to self antigen|upregulation of tolerance induction to self antigen|up-regulation of tolerance induction to self antigen													biological_process											owl:Class	
GO:0002649	biolink:NamedThing	regulation of tolerance induction to self antigen	Any process that modulates the frequency, rate, or extent of tolerance induction to self antigen.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1902374	biolink:NamedThing	regulation of rRNA catabolic process	Any process that modulates the frequency, rate or extent of rRNA catabolic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of rRNA catabolism|regulation of rRNA degradation|regulation of rRNA breakdown							bf	2013-08-22T15:20:59Z					biological_process											owl:Class	
GO:0018595	biolink:NamedThing	alpha-pinene monooxygenase activity	Catalysis of the reaction: alpha-pinene + O2 + 2 H+ + 2 e- = H2O + pinocarveol.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0716|RHEA:32891|EC:1.14.13.155									molecular_function											owl:Class	
GO:1990604	biolink:NamedThing	IRE1-TRAF2-ASK1 complex	A protein complex of the endoplasmic reticulum membrane that consists of IRE1 (Inositol-requiring enzyme-1), TRAF2 (TNF receptor-associated factor 2) and ASK1 (Apoptosis signal-regulating kinase 1, a MAP3K).	tmpzr1t_l9r_go_relaxed.owl	ERN1-TRAF2-ASK1 complex							bf	2015-01-13T15:03:04Z					cellular_component											owl:Class	
GO:0102386	biolink:NamedThing	phenylacetaldehyde reductase activity	Catalysis of the reaction: 2-phenylethanol + NADP = phenylacetaldehyde + NADPH + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-13536									molecular_function											owl:Class	
GO:0018270	biolink:NamedThing	GPI anchor biosynthetic process via N-alanyl-glycosylphosphatidylinositolethanolamine	The chemical reactions and pathways resulting in the formation of a C-terminal peptidyl-alanine ethanolamide-linked glycosylphosphatidylinositol (GPI) anchor following hydrolysis of an alanyl-peptide bond in the carboxy-terminal region of a membrane-associated protein.	tmpzr1t_l9r_go_relaxed.owl	GPI anchor formation via N-alanyl-glycosylphosphatidylinositolethanolamine|GPI anchor anabolism via N-alanyl-glycosylphosphatidylinositolethanolamine|GPI anchor synthesis via N-alanyl-glycosylphosphatidylinositolethanolamine				RESID:AA0163									biological_process											owl:Class	
GO:0044038	biolink:NamedThing	cell wall macromolecule biosynthetic process	The chemical reactions and pathways resulting in the formation of a macromolecule destined to form part of a cell wall.	tmpzr1t_l9r_go_relaxed.owl	cell wall macromolecule biosynthesis|cell wall macromolecule synthesis|cellular cell wall macromolecule biosynthetic process|cell wall macromolecule biosynthetic process at cellular level|cell wall macromolecule anabolism													biological_process											owl:Class	
GO:0044036	biolink:NamedThing	cell wall macromolecule metabolic process	The chemical reactions and pathways involving macromolecules forming, or destined to form, part of the cell wall. A cell wall is a rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells, maintaining their shape and protecting them from osmotic lysis.	tmpzr1t_l9r_go_relaxed.owl	cellular cell wall macromolecule metabolism|cellular cell wall macromolecule metabolic process											GO:0010382		biological_process											owl:Class	
GO:1905382	biolink:NamedThing	positive regulation of snRNA transcription by RNA polymerase II	Any process that activates or increases the frequency, rate or extent of snRNA transcription mediated by RNA polymerase II.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of snRNA transcription from RNA polymerase II promoter|positive regulation of snRNA transcription from RNA polymerase II promoter|activation of snRNA transcription from Pol II promoter|up regulation of snRNA transcription from RNA polymerase II promoter|up regulation of snRNA transcription from Pol II promoter|upregulation of snRNA transcription from RNA polymerase II promoter|positive regulation of snRNA transcription from Pol II promoter|activation of snRNA transcription from RNA polymerase II promoter|up-regulation of snRNA transcription from Pol II promoter|upregulation of snRNA transcription from Pol II promoter					An example of this is GTF2A1 in human (UniProt symbol P52655) in PMID:10022900 (inferred from direct assay).		bhm	2016-08-18T13:39:34Z					biological_process											owl:Class	
GO:0048536	biolink:NamedThing	spleen development	The process whose specific outcome is the progression of the spleen over time, from its formation to the mature structure. The spleen is a large vascular lymphatic organ composed of white and red pulp, involved both in hemopoietic and immune system functions.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1902301	biolink:NamedThing	galactarate transmembrane transporter activity	Enables the transfer of galactaric acid anion (galactarate) from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	D-galactarate transmembrane transporter activity|galactaric acid anion transmembrane transporter activity							pr	2013-07-16T07:26:36Z			GO:0042877		molecular_function											owl:Class	
GO:1902743	biolink:NamedThing	regulation of lamellipodium organization	Any process that modulates the frequency, rate or extent of lamellipodium organization.	tmpzr1t_l9r_go_relaxed.owl								als	2014-02-28T16:27:30Z					biological_process											owl:Class	
GO:0009852	biolink:NamedThing	auxin catabolic process	The chemical reactions and pathways resulting in the breakdown of auxins, a group of plant hormones that regulate aspects of plant growth.	tmpzr1t_l9r_go_relaxed.owl	auxin catabolism|auxin degradation|auxin breakdown													biological_process											owl:Class	
GO:0047424	biolink:NamedThing	methylenediurea deaminase activity	Catalysis of the reaction: 2 H2O + methylenediurea = CO2 + 2 NH3 + N-hydroxymethylurea.	tmpzr1t_l9r_go_relaxed.owl	methylenediurea aminohydrolase activity|methylenediurease activity				RHEA:15929|MetaCyc:3.5.3.21-RXN|EC:3.5.3.21									molecular_function											owl:Class	
GO:0033014	biolink:NamedThing	tetrapyrrole biosynthetic process	The chemical reactions and pathways leading to the formation of tetrapyrroles, natural pigments containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next.	tmpzr1t_l9r_go_relaxed.owl	tetrapyrrole anabolism|tetrapyrrole synthesis|tetrapyrrole biosynthesis|tetrapyrrole formation													biological_process											owl:Class	
GO:0071452	biolink:NamedThing	cellular response to singlet oxygen	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a singlet oxygen stimulus. Singlet oxygen is a dioxygen (O2) molecule in which two 2p electrons have similar spin. Singlet oxygen is more highly reactive than the form in which these electrons are of opposite spin, and it is produced in mutant chloroplasts lacking carotenoids and by leukocytes during metabolic burst.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-12-16T04:39:46Z					biological_process											owl:Class	
GO:0000304	biolink:NamedThing	response to singlet oxygen	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a singlet oxygen stimulus. Singlet oxygen is a dioxygen (O2) molecule in which two 2p electrons have similar spin. Singlet oxygen is more highly reactive than the form in which these electrons are of opposite spin, and it is produced in mutant chloroplasts lacking carotenoids and by leukocytes during metabolic burst.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0032547	biolink:NamedThing	purine deoxyribonucleoside binding	Binding to a purine deoxyribonucleoside, a compound consisting of a purine base linked to deoxyribose.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0001883	biolink:NamedThing	purine nucleoside binding	Binding to a purine nucleoside, a compound consisting of a purine base linked either to ribose or deoxyribose.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:2000258	biolink:NamedThing	negative regulation of protein activation cascade	Any process that stops, prevents or reduces the frequency, rate or extent of protein activation cascade.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of protein activitory cascade|negative regulation of protein activation pathway							mah	2010-11-23T11:33:51Z					biological_process											owl:Class	
GO:2000257	biolink:NamedThing	regulation of protein activation cascade	Any process that modulates the frequency, rate or extent of protein activation cascade.	tmpzr1t_l9r_go_relaxed.owl	regulation of protein activitory cascade|regulation of protein activation pathway							mah	2010-11-23T11:33:46Z					biological_process											owl:Class	
GO:0015801	biolink:NamedThing	aromatic amino acid transport	The directed movement of aromatic amino acids, amino acids with aromatic ring, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0019508	biolink:NamedThing	2,5-dihydroxypyridine catabolic process to fumarate	The chemical reactions and pathways resulting in the breakdown of 2,5-dihydroxypyridine to form fumarate. 2,5-dihydroxypyridine is dioxygenated to give maleamate and formate; the maleamate from this reaction is then converted to maleate, which is then isomerized to fumurate.	tmpzr1t_l9r_go_relaxed.owl	2,5-dihydroxypyridine degradation to fumarate|2,5-dihydroxypyridine utilization|2,5-dihydroxypyridine breakdown to fumarate|pyridine-2,5-diol catabolic process to fumarate|maleamate pathway				MetaCyc:PWY-722									biological_process											owl:Class	
GO:0051166	biolink:NamedThing	2,5-dihydroxypyridine catabolic process	The chemical reactions and pathways resulting in the breakdown of 2,5-dihydroxypyridine.	tmpzr1t_l9r_go_relaxed.owl	2,5-dihydroxypyridine degradation|2,5-dihydroxypyridine breakdown|2,5-dihydroxypyridine catabolism|pyridine-2,5-diol catabolic process													biological_process											owl:Class	
GO:0071691	biolink:NamedThing	cardiac muscle thin filament assembly	The aggregation, arrangement and bonding together of proteins to form the actin-based thin filaments of myofibrils in cardiac muscle.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-02-25T03:57:01Z					biological_process											owl:Class	
GO:0034002	biolink:NamedThing	(R)-limonene synthase activity	Catalysis of the reaction: geranyl diphosphate = (4R)-limonene + diphosphate.	tmpzr1t_l9r_go_relaxed.owl	geranyl-diphosphate diphosphate-lyase [cyclizing, (+)-(4R)-limonene-forming] activity|(+)-limonene synthase activity|geranyldiphosphate diphosphate lyase [(+)-(R)-limonene-forming] activity				KEGG_REACTION:R06120|RHEA:10940|EC:4.2.3.20|MetaCyc:4.2.3.20-RXN									molecular_function											owl:Class	
GO:1903188	biolink:NamedThing	positive regulation of vitellogenesis	Any process that activates or increases the frequency, rate or extent of vitellogenesis.	tmpzr1t_l9r_go_relaxed.owl	activation of yolk production|upregulation of yolk production|activation of vitellogenesis|positive regulation of yolk production|upregulation of vitellogenesis|up regulation of vitellogenesis|up regulation of yolk production|up-regulation of yolk production|up-regulation of vitellogenesis							mr	2014-07-14T19:28:12Z					biological_process											owl:Class	
GO:0052646	biolink:NamedThing	alditol phosphate metabolic process	The chemical reactions and pathways involving alditol phosphates, any phosphorylated polyhydric alcohol derived from the acyclic form of a monosaccharide by reduction of its aldehyde or keto group to an alcoholic group.	tmpzr1t_l9r_go_relaxed.owl	alditol phosphate metabolism							ai	2010-09-22T04:24:21Z					biological_process											owl:Class	
GO:0006264	biolink:NamedThing	mitochondrial DNA replication	The process in which new strands of DNA are synthesized in the mitochondrion.	tmpzr1t_l9r_go_relaxed.owl	mtDNA replication|replication of mitochondrial DNA|mitochondrial DNA synthesis|mtDNA synthesis													biological_process											owl:Class	
GO:0032758	biolink:NamedThing	positive regulation of interleukin-9 production	Any process that activates or increases the frequency, rate, or extent of interleukin-9 production.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of interleukin-9 production|positive regulation of IL-9 production|activation of interleukin-9 production|upregulation of interleukin-9 production|stimulation of interleukin-9 production|positive regulation of interleukin-9 biosynthetic process|up regulation of interleukin-9 production											GO:0045419		biological_process											owl:Class	
GO:0044345	biolink:NamedThing	stromal-epithelial cell signaling involved in prostate gland development	The process of transferring information from a stromal cell to an epithelial cell where it is received and interpreted, as part of prostate gland development.	tmpzr1t_l9r_go_relaxed.owl	stromal-epithelial cell signalling involved in prostate gland development							jl	2010-08-25T02:06:34Z					biological_process											owl:Class	
GO:0002593	biolink:NamedThing	negative regulation of antigen processing and presentation via MHC class Ib	Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of antigen via MHC class Ib.	tmpzr1t_l9r_go_relaxed.owl	downregulation of antigen processing and presentation via MHC class Ib|down-regulation of antigen processing and presentation via MHC class Ib|down regulation of antigen processing and presentation via MHC class Ib|inhibition of antigen processing and presentation via MHC class Ib													biological_process											owl:Class	
GO:0043921	biolink:NamedThing	modulation by host of viral transcription	Any process in which a host organism modulates the frequency, rate or extent of viral transcription.	tmpzr1t_l9r_go_relaxed.owl	regulation of viral transcription by host|regulation by host of viral transcription													biological_process											owl:Class	
GO:0044788	biolink:NamedThing	modulation by host of viral process	A process in which a host organism modulates the frequency, rate or extent of any of a process being mediated by a virus with which it is infected.	tmpzr1t_l9r_go_relaxed.owl								jl	2013-06-06T10:50:49Z					biological_process											owl:Class	
GO:0071268	biolink:NamedThing	homocysteine biosynthetic process	The chemical reactions and pathways resulting in the formation of homocysteine, 2-amino-4-sulfanylbutanoic acid.	tmpzr1t_l9r_go_relaxed.owl	homocysteine biosynthesis|homocysteine formation|homocysteine synthesis|homocysteine anabolism							mah	2009-12-09T05:32:48Z					biological_process											owl:Class	
GO:0071595	biolink:NamedThing	Nem1-Spo7 phosphatase complex	A protein serine/threonine phosphatase complex that is involved in nuclear envelope organization, and contains proteins known in budding yeast as Nem1p and Spo7p.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-01-29T02:17:29Z					cellular_component											owl:Class	
GO:0047372	biolink:NamedThing	acylglycerol lipase activity	Catalysis of the reaction: H2O + acylglycerol = a fatty acid + glycerol.	tmpzr1t_l9r_go_relaxed.owl	monoglyceridyllipase activity|monoacylglycerol hydrolase activity|monoglyceride lipase activity|monoglyceridase activity|monoglyceride hydrolase activity|fatty acyl monoester lipase activity|monoacylglycerol lipase activity|monoacylglycerolipase activity|glycerol-ester acylhydrolase activity				Reactome:R-HSA-426032|Reactome:R-HSA-192422|Reactome:R-HSA-163595|MetaCyc:3.1.1.23-RXN|Reactome:R-HSA-192430|Reactome:R-HSA-192434|Reactome:R-HSA-426043|Reactome:R-HSA-192475|EC:3.1.1.23|RHEA:34019|Reactome:R-HSA-1482543|Reactome:R-HSA-5694462|Reactome:R-HSA-192425									molecular_function											owl:Class	
GO:0008966	biolink:NamedThing	phosphoglucosamine mutase activity	Catalysis of the reaction: alpha-D-glucosamine 1-phosphate = D-glucosamine 6-phosphate.	tmpzr1t_l9r_go_relaxed.owl	D-glucosamine 1,6-phosphomutase activity|alpha-D-glucosamine 1,6-phosphomutase activity				RHEA:23424|MetaCyc:5.4.2.10-RXN|KEGG_REACTION:R02060|EC:5.4.2.10									molecular_function											owl:Class	
GO:0016868	biolink:NamedThing	intramolecular transferase activity, phosphotransferases	Catalysis of the transfer of a phosphate group from one position to another within a single molecule.	tmpzr1t_l9r_go_relaxed.owl	phosphotransferase activity, with regeneration of donors, apparently catalyzing intramolecular transfers|phosphomutase activity				EC:5.4.2.-							GO:0016777		molecular_function											owl:Class	
GO:0034392	biolink:NamedThing	negative regulation of smooth muscle cell apoptotic process	Any process that stops, prevents, or reduces the frequency, rate, or extent of smooth muscle cell apoptotic process.	tmpzr1t_l9r_go_relaxed.owl	down regulation of smooth muscle cell apoptosis|inhibition of smooth muscle cell apoptosis|negative regulation of smooth muscle cell apoptosis|down-regulation of smooth muscle cell apoptosis|negative regulation of SMC apoptosis|downregulation of smooth muscle cell apoptosis													biological_process											owl:Class	
GO:0010656	biolink:NamedThing	negative regulation of muscle cell apoptotic process	Any process that decreases the rate or frequency of muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a muscle cell and result in its death.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of muscle cell apoptosis													biological_process											owl:Class	
GO:0018287	biolink:NamedThing	iron incorporation into iron-sulfur cluster via tris-L-cysteinyl triiron tetrasulfide	The incorporation of iron into a 3Fe-4S iron-sulfur cluster via tris-L-cysteinyl triiron tetrasulfide.	tmpzr1t_l9r_go_relaxed.owl	iron incorporation into iron-sulphur cluster via tris-L-cysteinyl triiron tetrasulphide				RESID:AA0139									biological_process											owl:Class	
GO:0060335	biolink:NamedThing	positive regulation of interferon-gamma-mediated signaling pathway	Any process that increases the rate, frequency or extent of the series of molecular events generated as a consequence of interferon-gamma binding to a cell surface receptor.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of gamma-interferon-mediated signaling pathway|positive regulation of type II IFN-mediated pathway|positive regulation of interferon-gamma-mediated signalling pathway|positive regulation of type II interferon-mediated signaling pathway|positive regulation of immune interferon-mediated signaling pathway													biological_process											owl:Class	
GO:0015015	biolink:NamedThing	heparan sulfate proteoglycan biosynthetic process, enzymatic modification	The modification, often by sulfation, of sugars incorporated into heparan sulfate after polymerization.	tmpzr1t_l9r_go_relaxed.owl	heparan sulfate proteoglycan anabolism, enzymatic modification|heparan sulfate proteoglycan synthesis, enzymatic modification|heparin proteoglycan biosynthetic process, enzymatic modification|heparan sulphate proteoglycan biosynthesis, enzymatic modification|heparan sulphate proteoglycan biosynthetic process, enzymatic modification|heparan sulfate proteoglycan formation, enzymatic modification													biological_process											owl:Class	
GO:0030201	biolink:NamedThing	heparan sulfate proteoglycan metabolic process	The chemical reactions and pathways involving any proteoglycan containing heparan sulfate, any member of a group of glycosaminoglycans that have repeat units consisting of alternating alpha-(1->4)-linked hexuronic acid and glucosamine residues, the former being a mixture of sulfated and nonsulfated D-glucuronic and L-iduronic acids, and the latter being either sulfated or acetylated on its amino group as well as sulfated on one of its hydroxyl groups.	tmpzr1t_l9r_go_relaxed.owl	heparan sulfate proteoglycan metabolism|heparin proteoglycan metabolic process|heparan sulphate proteoglycan metabolism|heparan sulphate proteoglycan metabolic process													biological_process											owl:Class	
GO:0015369	biolink:NamedThing	calcium:proton antiporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Ca2+(in) + H+(out) = Ca2+(out) + H+(in).	tmpzr1t_l9r_go_relaxed.owl	calcium:hydrogen antiporter activity				RHEA:29671|Reactome:R-HSA-8949687									molecular_function											owl:Class	
GO:0005451	biolink:NamedThing	monovalent cation:proton antiporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: monovalent cation(out) + H+(in) = monovalent cation(in) + H+(out).	tmpzr1t_l9r_go_relaxed.owl	monovalent cation:hydrogen antiporter activity				Reactome:R-HSA-2889070									molecular_function											owl:Class	
GO:0030523	biolink:NamedThing	dihydrolipoamide S-acyltransferase activity	Catalysis of the reaction: acyl-CoA + dihydrolipoamide = CoA + S-acyldihydrolipoamide.	tmpzr1t_l9r_go_relaxed.owl					EC:2.3.1.12									molecular_function											owl:Class	
GO:0010542	biolink:NamedThing	nitrate efflux transmembrane transporter activity	Enables the transfer of nitrate from the inside of the cell to the outside of the cell across a membrane.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0015562	biolink:NamedThing	efflux transmembrane transporter activity	Enables the transfer of a specific substance or related group of substances from the inside of the cell to the outside of the cell across a membrane.	tmpzr1t_l9r_go_relaxed.owl	efflux transporter activity|efflux permease activity|monocarboxylate (lactate, pyruvate, mevalonate) uptake/efflux porter activity													molecular_function											owl:Class	
GO:0033377	biolink:NamedThing	maintenance of protein location in T cell secretory granule	A process in which a protein is maintained in a secretory granule in a T cell and prevented from moving elsewhere.	tmpzr1t_l9r_go_relaxed.owl	maintenance of protein localization in T cell secretory granule|maintenance of protein localization in T-cell secretory granule|maintenance of protein localization in T lymphocyte secretory granule|maintenance of protein localization in T-lymphocyte secretory granule													biological_process											owl:Class	
GO:0106112	biolink:NamedThing	negative regulation of mitotic cohesin ssDNA (lagging strand) loading	Any process that stops, prevents or reduces the frequency, rate or extent of mitotic cohesin ssDNA (lagging strand) loading.	tmpzr1t_l9r_go_relaxed.owl								hjd	2018-04-18T14:41:50Z					biological_process											owl:Class	
GO:0002112	biolink:NamedThing	interleukin-33 receptor binding	Binding to an interleukin-33 receptor.	tmpzr1t_l9r_go_relaxed.owl	IL-33|interleukin-33 receptor ligand													molecular_function											owl:Class	
GO:0071578	biolink:NamedThing	zinc ion import across plasma membrane	The directed movement of zinc(2+) ions from outside of a cell, across the plasma membrane and into the cytosol.	tmpzr1t_l9r_go_relaxed.owl	zinc ion transmembrane import|high-affinity zinc II ion transport|zinc uptake|zinc import|high-affinity zinc II ion transmembrane import|zinc II ion plasma membrane import|zinc II ion transmembrane import|low-affinity zinc II ion transport							jl	2010-01-28T02:22:02Z			GO:0006831|GO:0044749|GO:0006830|GO:0140160		biological_process											owl:Class	
GO:1901455	biolink:NamedThing	negative regulation of response to toluene	Any process that stops, prevents or reduces the frequency, rate or extent of response to toluene.	tmpzr1t_l9r_go_relaxed.owl	down regulation of response to toluene|inhibition of response to toluene|down-regulation of response to toluene|downregulation of response to toluene							tt	2012-10-02T14:23:28Z					biological_process											owl:Class	
GO:0047630	biolink:NamedThing	ADP-phosphoglycerate phosphatase activity	Catalysis of the reaction: 3-ADP-2-phosphoglycerate + H(2)O = 3-ADP-glycerate + phosphate.	tmpzr1t_l9r_go_relaxed.owl	3-(ADP)-2-phosphoglycerate phosphohydrolase activity|ADPphosphoglycerate phosphatase activity|adenosine diphosphate phosphoglycerate phosphatase activity				KEGG_REACTION:R03969|RHEA:15861|MetaCyc:ADP-PHOSPHOGLYCERATE-PHOSPHATASE-RXN|EC:3.1.3.28									molecular_function											owl:Class	
GO:0102576	biolink:NamedThing	3-oxo-palmitoyl-ACP hydrolase activity	Catalysis of the reaction: H2O + a 3-oxo-palmitoyl-[acp] = 3-oxopalmitic acid + H+ + a holo-[acyl-carrier protein].	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-15282									molecular_function											owl:Class	
GO:1902250	biolink:NamedThing	regulation of erythrocyte apoptotic process	Any process that modulates the frequency, rate or extent of erythrocyte apoptotic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of erythrocyte apoptosis|regulation of red blood cell apoptotic process|regulation of red blood cell apoptosis|regulation of RBC apoptotic process|regulation of RBC apoptosis							rl	2013-06-20T19:30:53Z					biological_process											owl:Class	
GO:0030108	biolink:NamedThing	HLA-A specific activating MHC class I receptor activity	Combining with a MHC class I molecule of the HLA-A subclass to mediate signaling that activates a lymphocyte.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0032397	biolink:NamedThing	activating MHC class I receptor activity	Combining with a MHC class I protein complex to mediate signaling that activates a lymphocyte.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0018263	biolink:NamedThing	isopeptide cross-linking via N-(L-isoaspartyl)-L-cysteine	The formation of an isopeptide cross-link between peptidyl-asparagine and peptidyl-cysteine to produce N-(L-isoaspartyl)-L-cysteine.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0216									biological_process											owl:Class	
GO:0032511	biolink:NamedThing	late endosome to vacuole transport via multivesicular body sorting pathway	The directed movement of substances from endosomes to vacuoles by a pathway in which molecules are sorted into multivesicular bodies, which then fuse with the vacuole.	tmpzr1t_l9r_go_relaxed.owl	endosome to vacuole transport via MVB sorting pathway													biological_process											owl:Class	
GO:0032509	biolink:NamedThing	endosome transport via multivesicular body sorting pathway	The directed movement of substances from endosomes to lysosomes or vacuoles by a pathway in which molecules are sorted into multivesicular bodies, which then fuse with the target compartment.	tmpzr1t_l9r_go_relaxed.owl	endosome transport via MVB sorting pathway													biological_process											owl:Class	
GO:0090366	biolink:NamedThing	positive regulation of mRNA modification	Any process that increases the rate, frequency, or extent of the covalent alteration of one or more nucleotides within an mRNA molecule to produce an mRNA molecule with a sequence that differs from that coded genetically.	tmpzr1t_l9r_go_relaxed.owl								tb	2010-07-12T11:04:45Z					biological_process											owl:Class	
GO:0090365	biolink:NamedThing	regulation of mRNA modification	Any process that modulates the rate, frequency, or extent of the covalent alteration of one or more nucleotides within an mRNA molecule to produce an mRNA molecule with a sequence that differs from that coded genetically.	tmpzr1t_l9r_go_relaxed.owl	regulation of mRNA editing							tb	2010-07-12T11:04:45Z					biological_process											owl:Class	
GO:0010859	biolink:NamedThing	calcium-dependent cysteine-type endopeptidase inhibitor activity	Binds to and stops, prevents or reduces the activity of a calcium-dependent cysteine-type endopeptidase, any enzyme that hydrolyzes peptide bonds in polypeptides by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile in a calcium-dependent manner.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0004869	biolink:NamedThing	cysteine-type endopeptidase inhibitor activity	Binds to and stops, prevents or reduces the activity of a cysteine-type endopeptidase, any enzyme that hydrolyzes peptide bonds in polypeptides by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile.	tmpzr1t_l9r_go_relaxed.owl	cysteine protease inhibitor activity|cystatin|thiol protease inhibitor											GO:0004870		molecular_function											owl:Class	
GO:1905623	biolink:NamedThing	positive regulation of leaf development	Any process that activates or increases the frequency, rate or extent of leaf development.	tmpzr1t_l9r_go_relaxed.owl	upregulation of leaf development|up regulation of leaf development|activation of leaf development|up-regulation of leaf development							pga	2016-10-28T15:30:04Z					biological_process											owl:Class	
GO:0045283	biolink:NamedThing	fumarate reductase complex	A membrane-bound flavoenzyme complex consisting of four subunits, A, B, C, and D. A and B comprise the membrane-extrinsic catalytic domain and C (InterPro:IPR003510; InterPro:IPR004224) and D (InterPro:IPR003418) link the catalytic centers to the electron-transport chain. This family consists of the 13 kDa hydrophobic subunit D. This component may be required to anchor the catalytic components of the fumarate reductase complex to the cytoplasmic membrane. Fumarate reductase couples the reduction of fumarate to succinate to the oxidation of quinol to quinone, in a reaction opposite to that catalyzed by the related complex II of the respiratory chain (succinate dehydrogenase-(ubiquinone)).	tmpzr1t_l9r_go_relaxed.owl						See also the molecular function term 'succinate dehydrogenase (ubiquinone) activity ; GO:0008177'.								cellular_component											owl:Class	
GO:0001741	biolink:NamedThing	XY body	A structure found in a male mammalian spermatocyte containing an unpaired X chromosome that has become densely heterochromatic, silenced and localized at the nuclear periphery.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0000803	biolink:NamedThing	sex chromosome	A chromosome involved in sex determination.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0043685	biolink:NamedThing	conversion of glutamyl-tRNA to glutaminyl-tRNA	The modification process that results in the conversion of glutamate charged on a tRNA(Gln) to glutaminyl-tRNA.	tmpzr1t_l9r_go_relaxed.owl						Note that this process has been observed in some archaeal and bacterial species.								biological_process											owl:Class	
GO:0019988	biolink:NamedThing	charged-tRNA amino acid modification	The covalent alteration of an amino acid charged on a tRNA before it is incorporated into a protein, as in N-formylmethionine, selenocysteine or pyrrolysine.	tmpzr1t_l9r_go_relaxed.owl	pretranslation protein modification|pretranslational amino acid modification|charged-tRNA modification|charged tRNA modification|charged tRNA amino acid modification|pre-translational protein modification|pre-translational amino acid modification											GO:0030630		biological_process											owl:Class	
GO:0048815	biolink:NamedThing	hermaphrodite genitalia morphogenesis	The process in which the anatomical structures of hermaphrodite genitalia are generated and organized.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0097215	biolink:NamedThing	negative regulation of lysosomal membrane permeability	Any process that decreases the frequency, rate or extent of the passage or uptake of molecules by the lysosomal membrane.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of lysosome membrane permeability							pr	2012-01-12T10:23:42Z					biological_process											owl:Class	
GO:1905709	biolink:NamedThing	negative regulation of membrane permeability	Any process that stops, prevents or reduces the frequency, rate or extent of the passage or uptake of molecules by a membrane.	tmpzr1t_l9r_go_relaxed.owl								hbye	2016-11-18T13:10:42Z					biological_process											owl:Class	
GO:0046516	biolink:NamedThing	hypusine metabolic process	The chemical reactions and pathways involving hypusine, N6-(4-amino-2-hydroxybutyl)-L-lysine.	tmpzr1t_l9r_go_relaxed.owl	hypusine metabolism													biological_process											owl:Class	
GO:0046967	biolink:NamedThing	cytosol to endoplasmic reticulum transport	The directed movement of substances from the cytosol to the endoplasmic reticulum of a cell.	tmpzr1t_l9r_go_relaxed.owl	cytosol to ER transport													biological_process											owl:Class	
GO:0001575	biolink:NamedThing	globoside metabolic process	The chemical reactions and pathways involving globosides, globotetraosylceramides, ceramides containing a core structure of GalNAc-beta-(1->3)-Gal-alpha-(1->4)-Glc(I). Globosides are the major neutral glycosphingolipid in normal kidneys and erythrocytes.	tmpzr1t_l9r_go_relaxed.owl	globoside metabolism													biological_process											owl:Class	
GO:0006687	biolink:NamedThing	glycosphingolipid metabolic process	The chemical reactions and pathways involving glycosphingolipids, any compound with residues of sphingoid and at least one monosaccharide.	tmpzr1t_l9r_go_relaxed.owl	glycosphingolipid metabolism													biological_process											owl:Class	
GO:0046404	biolink:NamedThing	polydeoxyribonucleotide 5'-hydroxyl-kinase activity	Catalysis of the reaction: ATP + 5'-dephospho-DNA = ADP + 5'-phospho-DNA.	tmpzr1t_l9r_go_relaxed.owl	ATP-dependent DNA kinase activity|ATP-dependent polynucleotide 5'-hydroxyl-kinase activity|ATP:5'-dephosphopolydeoxyribonucleotide 5'-phosphotransferase activity|ATP-dependent DNA 5'-hydroxyl-kinase activity|ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity	https://github.com/geneontology/go-ontology/issues/21619			MetaCyc:POLYNUCLEOTIDE-5-HYDROXYL-KINASE-RXN|KEGG_REACTION:R03840|RHEA:15669|EC:2.7.1.78									molecular_function											owl:Class	
GO:0051733	biolink:NamedThing	polydeoxyribonucleotide kinase activity	Catalysis of the reaction: NTP + 5'-dephospho-DNA = NDP + 5'-phospho-DNA.	tmpzr1t_l9r_go_relaxed.owl	DNA kinase activity|DNA 5'-hydroxyl kinase activity													molecular_function											owl:Class	
GO:0097017	biolink:NamedThing	renal protein absorption	A renal system process in which proteins are taken up from the collecting ducts, glomerulus and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures (e.g. protein absorption is observed in nephrocytes in Drosophila, see PMID:23264686).	tmpzr1t_l9r_go_relaxed.owl								pr	2011-03-23T03:13:04Z					biological_process											owl:Class	
GO:0140300	biolink:NamedThing	serine import into mitochondrion	The process in which serine is transported from the cytosol into the mitochondrial matrix.	tmpzr1t_l9r_go_relaxed.owl								pg	2018-12-13T15:17:50Z					biological_process											owl:Class	
GO:0034267	biolink:NamedThing	discadenine metabolic process	The chemical reactions and pathways involving discadenine, (2S)-2-amino-4-{6-[(3-methylbut-2-en-1-yl)amino]-3H-purin-3-yl}butanoic acid.	tmpzr1t_l9r_go_relaxed.owl	discadenine metabolism													biological_process											owl:Class	
GO:0004468	biolink:NamedThing	lysine N-acetyltransferase activity, acting on acetyl phosphate as donor	Catalysis of the reaction: acetyl phosphate + L-lysine = phosphate + N6-acetyl-L-lysine.	tmpzr1t_l9r_go_relaxed.owl	lysine N6-acetyltransferase activity|lysine N(6)-acetyltransferase activity|lysine acetyltransferase activity|acetyl-phosphate:L-lysine 6-N-acetyltransferase activity|LAT activity|acetyl-phosphate:L-lysine N6-acetyltransferase activity				Reactome:R-HSA-5618328|Reactome:R-HSA-5693001|RHEA:14417|MetaCyc:LYSINE-N-ACETYLTRANSFERASE-RXN|EC:2.3.1.32									molecular_function											owl:Class	
GO:0030771	biolink:NamedThing	N-benzoyl-4-hydroxyanthranilate 4-O-methyltransferase activity	Catalysis of the reaction: N-benzoyl-4-hydroxyanthranilate + S-adenosyl-L-methionine(1+) = N-benzoyl-4-methoxyanthranilate + S-adenosyl-L-homocysteine + H(+).	tmpzr1t_l9r_go_relaxed.owl	benzoyl-CoA:anthranilate N-benzoyltransferase|N-benzoyl-4-hydroxyanthranilate 4-methyltransferase activity|S-adenosyl-L-methionine:N-benzoyl-4-O-hydroxyanthranilate 4-O-methyltransferase activity				RHEA:17405|KEGG_REACTION:R04421|MetaCyc:2.1.1.105-RXN|EC:2.1.1.105									molecular_function											owl:Class	
GO:0032154	biolink:NamedThing	cleavage furrow	The cleavage furrow is a plasma membrane invagination at the cell division site. The cleavage furrow begins as a shallow groove and eventually deepens to divide the cytoplasm.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Cleavage_furrow	While the term 'cleavage furrow' was initially associated with animal cells, such a structure occurs in many other types of cells, including unicellular protists.								cellular_component											owl:Class	
GO:0045174	biolink:NamedThing	glutathione dehydrogenase (ascorbate) activity	Catalysis of the reaction: dehydroascorbate + 2 glutathione = L-ascorbate + glutathione disulfide.	tmpzr1t_l9r_go_relaxed.owl	glutathione:dehydroascorbate oxidoreductase activity|glutathione:dehydroascorbic acid oxidoreductase activity|dehydroascorbic reductase activity|GDOR|glutathione dehydroascorbate reductase activity|DHA reductase activity|dehydroascorbate reductase activity|dehydroascorbic acid reductase activity				Reactome:R-HSA-198813|EC:1.8.5.1|MetaCyc:1.8.5.1-RXN|RHEA:24424|KEGG_REACTION:R01108									molecular_function											owl:Class	
GO:0015038	biolink:NamedThing	glutathione disulfide oxidoreductase activity	Catalysis of the reaction: 2 glutathione + electron acceptor = glutathione disulfide + electron donor.	tmpzr1t_l9r_go_relaxed.owl	glutathione disulphide oxidoreductase activity|glutaredoxin				Reactome:R-HSA-111746									molecular_function											owl:Class	
GO:0120083	biolink:NamedThing	rough endoplasmic reticulum cisterna	A subcompartment of the rough endoplasmic reticulum consisting of lumenal expansion into a flattened, disc-shaped cavity.	tmpzr1t_l9r_go_relaxed.owl								krc	2017-07-05T23:38:49Z					cellular_component											owl:Class	
GO:0072144	biolink:NamedThing	glomerular mesangial cell development	The process whose specific outcome is the progression of a glomerular mesangial cell in the kidney over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-02-24T01:53:13Z					biological_process											owl:Class	
GO:0120211	biolink:NamedThing	proacrosomal vesicle fusion	Fusion of the membrane of proacrosomal vesicle with the membrane of another proacrosomal vesicle to form the acrosome.	tmpzr1t_l9r_go_relaxed.owl								krc	2019-05-22T17:12:55Z					biological_process											owl:Class	
GO:0075244	biolink:NamedThing	regulation of oospore formation	Any process that modulates the frequency, rate or extent of oospore formation, a process in which male and female gametangia develop and fuse to form a thick-walled resting spore of oomycetes.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0047947	biolink:NamedThing	glutamine N-phenylacetyltransferase activity	Catalysis of the reaction: phenylacetyl-CoA + L-glutamine = CoA + alpha-N-phenylacetyl-L-glutamine.	tmpzr1t_l9r_go_relaxed.owl	glutamine phenylacetyltransferase activity|phenylacetyl-CoA:L-glutamine N-acetyltransferase activity|phenylacetyl-CoA:L-glutamine alpha-N-phenylacetyltransferase activity				RHEA:21844|EC:2.3.1.14|MetaCyc:GLUTAMINE-N-PHENYLACETYLTRANSFERASE-RXN									molecular_function											owl:Class	
GO:2000799	biolink:NamedThing	positive regulation of amniotic stem cell differentiation	Any process that activates or increases the frequency, rate or extent of amniotic stem cell differentiation.	tmpzr1t_l9r_go_relaxed.owl								yaf	2011-06-29T02:19:06Z					biological_process											owl:Class	
GO:1900798	biolink:NamedThing	cordyol C catabolic process	The chemical reactions and pathways resulting in the breakdown of cordyol C.	tmpzr1t_l9r_go_relaxed.owl	cordyol C catabolism|cordyol C degradation|cordyol C breakdown							di	2012-06-04T09:48:10Z					biological_process											owl:Class	
GO:0043539	biolink:NamedThing	protein serine/threonine kinase activator activity	Binds to and increases the activity of a protein serine/threonine kinase.	tmpzr1t_l9r_go_relaxed.owl	protein ser/thr kinase activator activity													molecular_function											owl:Class	
GO:0010918	biolink:NamedThing	positive regulation of mitochondrial membrane potential	Any process that activates or increases the frequency, rate or extent of establishment or extent of a mitochondrial membrane potential, the electric potential existing across any mitochondrial membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane.	tmpzr1t_l9r_go_relaxed.owl	elevation of mitochondrial membrane potential													biological_process											owl:Class	
GO:0051881	biolink:NamedThing	regulation of mitochondrial membrane potential	Any process that modulates the establishment or extent of the mitochondrial membrane potential, the electric potential existing across the mitochondrial membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0098947	biolink:NamedThing	intrinsic component of postsynaptic endocytic zone membrane	The component of the postsynaptic endocytic zone membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.	tmpzr1t_l9r_go_relaxed.owl	intrinsic to postsynaptic acive zone membrane													cellular_component											owl:Class	
GO:1903659	biolink:NamedThing	regulation of complement-dependent cytotoxicity	Any process that modulates the frequency, rate or extent of complement-dependent cytotoxicity.	tmpzr1t_l9r_go_relaxed.owl								jl	2014-11-25T15:03:54Z					biological_process											owl:Class	
GO:0044355	biolink:NamedThing	clearance of foreign intracellular DNA	A defense process that protects an organism from invading foreign DNA.	tmpzr1t_l9r_go_relaxed.owl	clearance of foreign intracellular DNA by conversion of DNA cytidine to uridine	https://github.com/geneontology/go-ontology/issues/18727						jl	2011-08-11T11:25:43Z			GO:0044356		biological_process											owl:Class	
GO:0099046	biolink:NamedThing	clearance of foreign intracellular nucleic acids	A defense process that protects an organism from DNA or RNA from an invading organism.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1900026	biolink:NamedThing	positive regulation of substrate adhesion-dependent cell spreading	Any process that activates or increases the frequency, rate or extent of substrate adhesion-dependent cell spreading.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of substrate adhesion dependent cell spreading|up regulation of substrate adhesion-dependent cell spreading|up regulation of cell spreading during cell substrate adhesion|up regulation of substrate adhesion dependent cell spreading|positive regulation of cell spreading during cell substrate adhesion							yaf	2012-01-12T05:00:46Z					biological_process											owl:Class	
GO:0010770	biolink:NamedThing	positive regulation of cell morphogenesis involved in differentiation	Any process that increases the frequency, rate or extent of cell morphogenesis contributing to cell differentiation. Cell morphogenesis involved in differentiation is the change in form (cell shape and size) that occurs when relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0042840	biolink:NamedThing	D-glucuronate catabolic process	The chemical reactions and pathways resulting in the breakdown of D-glucuronate, the D-enantiomer of glucuronate.	tmpzr1t_l9r_go_relaxed.owl	D-glucuronate degradation|D-glucuronate breakdown|D-glucuronate catabolism													biological_process											owl:Class	
GO:0042839	biolink:NamedThing	D-glucuronate metabolic process	The chemical reactions and pathways involving D-glucuronate, the D-enantiomer of glucuronate.	tmpzr1t_l9r_go_relaxed.owl	D-glucuronate metabolism													biological_process											owl:Class	
GO:0070095	biolink:NamedThing	fructose-6-phosphate binding	Binding to fructose 6-phosphate.	tmpzr1t_l9r_go_relaxed.owl	D-fructose 6-phosphate binding|fructose 6-phosphate binding													molecular_function											owl:Class	
GO:1903301	biolink:NamedThing	positive regulation of hexokinase activity	Any process that activates or increases the frequency, rate or extent of hexokinase activity.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of hexokinase type III activity|activation of hexokinase type IV|up-regulation of hexokinase type IV glucokinase activity|up-regulation of hexokinase (phosphorylating)|up-regulation of hexokinase type I activity|activation of hexokinase (phosphorylating)|up regulation of hexokinase activity|up-regulation of glucose ATP phosphotransferase activity|positive regulation of glucose ATP phosphotransferase activity|up-regulation of hexokinase type IV (glucokinase) activity|upregulation of hexokinase type IV (glucokinase) activity|activation of hexokinase type I activity|positive regulation of ATP-dependent hexokinase activity|positive regulation of hexokinase type II activity|positive regulation of hexokinase type IV|up regulation of hexokinase type III activity|activation of glucose ATP phosphotransferase activity|activation of hexokinase type IV glucokinase activity|activation of hexokinase activity|up-regulation of hexokinase activity|upregulation of hexokinase type II activity|activation of hexokinase type IV (glucokinase) activity|activation of hexokinase type II activity|upregulation of hexokinase type I activity|up regulation of hexokinase type II activity|up-regulation of hexokinase D|up-regulation of ATP:D-hexose 6-phosphotransferase activity|upregulation of hexokinase type III activity|up regulation of glucose ATP phosphotransferase activity|positive regulation of hexokinase type IV glucokinase activity|activation of hexokinase D|up regulation of ATP-dependent hexokinase activity|upregulation of hexokinase D|up-regulation of ATP-dependent hexokinase activity|up regulation of hexokinase D|activation of ATP:D-hexose 6-phosphotransferase activity|positive regulation of ATP:D-hexose 6-phosphotransferase activity|up regulation of hexokinase type IV (glucokinase) activity|positive regulation of hexokinase D|upregulation of hexokinase type IV|up-regulation of hexokinase type II activity|positive regulation of hexokinase (phosphorylating)|positive regulation of hexokinase type IV (glucokinase) activity|activation of hexokinase type III activity|up-regulation of hexokinase type IV|upregulation of hexokinase type IV glucokinase activity|upregulation of glucose ATP phosphotransferase activity|up regulation of ATP:D-hexose 6-phosphotransferase activity|upregulation of hexokinase activity|positive regulation of hexokinase type I activity|up regulation of hexokinase (phosphorylating)|up-regulation of hexokinase type III activity|up regulation of hexokinase type I activity|activation of ATP-dependent hexokinase activity|up regulation of hexokinase type IV|upregulation of hexokinase (phosphorylating)|upregulation of ATP-dependent hexokinase activity|up regulation of hexokinase type IV glucokinase activity|upregulation of ATP:D-hexose 6-phosphotransferase activity							mr	2014-08-15T23:18:09Z					biological_process											owl:Class	
GO:0022001	biolink:NamedThing	negative regulation of anterior neural cell fate commitment of the neural plate	Any process that stops, prevents or reduces the frequency or rate at which a cell adopts an anterior neural cell fate.	tmpzr1t_l9r_go_relaxed.owl	posteriorization|downregulation of anterior neural cell fate of the neural plate|inhibition of anterior neural cell fate of the neural plate|negative regulation of anterior neural cell fate of the neural plate|caudalization of neural plate|down-regulation of anterior neural cell fate of the neural plate|down regulation of anterior neural cell fate of the neural plate													biological_process											owl:Class	
GO:0086020	biolink:NamedThing	gap junction channel activity involved in SA node cell-atrial cardiac muscle cell electrical coupling	A wide pore channel activity that enables a direct cytoplasmic connection from an SA node cell to an atrial cardiomyocyte. The gap junction passes electrical signals between the cells contributing to cardiac conduction.	tmpzr1t_l9r_go_relaxed.owl	gap junction channel activity involved in SA node cell-atrial cardiomyocyte electrical coupling|gap junction channel activity involved in sinoatrial node cell-atrial cardiomyocyte electrical coupling|gap junction channel activity involved in sinus node cell-atrial cardiomyocyte electrical coupling|gap junction channel activity involved in SAN cell-atrial cardiomyocyte electrical coupling							tb	2011-11-11T02:08:19Z					molecular_function											owl:Class	
GO:0000153	biolink:NamedThing	cytoplasmic ubiquitin ligase complex	A ubiquitin ligase complex found in the cytoplasm.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0051360	biolink:NamedThing	peptide cross-linking via L-asparagine 5-imidazolinone glycine	The formation of the fluorescent protein FP506 chromophore cross-link from the alpha-carboxyl carbon of residue n, an asparagine, to the alpha-amino nitrogen of residue n+2, a glycine, and a dehydration to form a double bond to the alpha-amino nitrogen of residue n+1. This cross-linking is coupled with a dehydrogenation of residue n+1 to form a double bond between the alpha and beta carbons.	tmpzr1t_l9r_go_relaxed.owl	biosynthetic process of protein-protein cross-link via L-asparagine 5-imidazolinone glycine|biosynthesis of protein-protein cross-link via L-asparagine 5-imidazolinone glycine				RESID:AA0380	See also the biological process term 'peptidyl-tyrosine dehydrogenation ; GO:0018251'.								biological_process											owl:Class	
GO:0018359	biolink:NamedThing	protein-heme P460 linkage via heme P460-bis-L-cysteine-L-tyrosine	The linkage of protein to heme P460 via heme P460-bis-L-cysteine-L-tyrosine.	tmpzr1t_l9r_go_relaxed.owl	protein-haem P460 linkage via haem P460-bis-L-cysteine-L-tyrosine				RESID:AA0266							GO:0018385		biological_process											owl:Class	
GO:0097224	biolink:NamedThing	sperm connecting piece	The segment of the sperm flagellum that attaches to the implantation fossa of the nucleus in the sperm head; from the remnant of the centriole at this point, the axoneme extends throughout the length of the flagellum.	tmpzr1t_l9r_go_relaxed.owl								pr	2012-01-25T01:21:02Z					cellular_component											owl:Class	
GO:0045869	biolink:NamedThing	negative regulation of single stranded viral RNA replication via double stranded DNA intermediate	Any process that stops, prevents, or reduces the frequency, rate or extent of single stranded viral RNA replication via double stranded DNA intermediate.	tmpzr1t_l9r_go_relaxed.owl	down regulation of retroviral genome replication|inhibition of retroviral genome replication|negative regulation of retroviral genome replication|downregulation of retroviral genome replication|down-regulation of retroviral genome replication|regulation of retroviral genome replication													biological_process											owl:Class	
GO:0045091	biolink:NamedThing	regulation of single stranded viral RNA replication via double stranded DNA intermediate	Any process that modulates the frequency, rate or extent of single stranded viral RNA replication via double stranded DNA intermediate.	tmpzr1t_l9r_go_relaxed.owl	regulation of retroviral genome replication													biological_process											owl:Class	
GO:0140332	biolink:NamedThing	lipopolysaccharide transfer activity	Removes a lipopolysaccharide (LPS) from the outer leaflet of a donor membrane, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to the outer leaflet of an acceptor membrane.	tmpzr1t_l9r_go_relaxed.owl	intermembrane lipopolysaccharide transfer activity|intermembrane LPS transporter activity|intermembrane lipopolysaccharide transporter activity|lipopolysaccharide carrier activity							pg	2019-05-13T08:17:35Z					molecular_function											owl:Class	
GO:0070455	biolink:NamedThing	positive regulation of heme biosynthetic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of heme.	tmpzr1t_l9r_go_relaxed.owl	activation of heme biosynthetic process|positive regulation of heme formation|upregulation of heme biosynthetic process|positive regulation of haem biosynthetic process|up regulation of heme biosynthetic process|positive regulation of heme anabolism|stimulation of heme biosynthetic process|positive regulation of heme biosynthesis|up-regulation of heme biosynthetic process|positive regulation of heme synthesis													biological_process											owl:Class	
GO:0034304	biolink:NamedThing	actinomycete-type spore formation	The process in which differentiated, resting cells are formed from a substrate mycelium; characteristic of many members of the order Actinomycetales.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0034285	biolink:NamedThing	response to disaccharide	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disaccharide stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to disaccharide stimulus													biological_process											owl:Class	
GO:0010472	biolink:NamedThing	GDP-galactose:glucose-1-phosphate guanylyltransferase activity	Catalysis of the reaction: GDP-L-galactose + alpha-D-glucose 1-phosphate = alpha-L-galactose-1-phosphate + GDP-alpha-D-glucose.	tmpzr1t_l9r_go_relaxed.owl	GDP-L-galactose phosphorylase activity|GDP-L-galactose:glucose-1-phosphate guanylyltransferase activity				MetaCyc:RXN4FS-13									molecular_function											owl:Class	
GO:0043430	biolink:NamedThing	2-decaprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity	Catalysis of the reaction: 2-decaprenyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-methionine = 2-decaprenyl-3-methyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-homocysteine.	tmpzr1t_l9r_go_relaxed.owl	2-decaprenyl-6-methoxy-1,4-benzoquinone methylase activity				RHEA:44764|Reactome:R-HSA-2162188	Note that the polyprenyl sidechain substrate for these methyltransferases varies in length between species, for example, 6 units in S. cerevisae, 8 units in E. coli and 10 units in G. suboxidans. Where the length of the substrate polyprenyl chain is unknown, the term '2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity ; GO:0008425' should be used.								molecular_function											owl:Class	
GO:0018172	biolink:NamedThing	peptidyl-L-3',4',5'-trihydroxyphenylalanine biosynthetic process from peptidyl-tyrosine	The modification of protein tyrosine to peptidyl-L-3',4',5'-dihydroxyphenylalanine.	tmpzr1t_l9r_go_relaxed.owl	peptidyl-L-3',4',5'-trihydroxyphenylalanine anabolism from peptidyl-tyrosine|peptidyl-L-3',4',5'-trihydroxyphenylalanine synthesis from peptidyl-tyrosine|peptidyl-L-3',4',5'-trihydroxyphenylalanine formation from peptidyl-tyrosine				RESID:AA0263									biological_process											owl:Class	
GO:1905198	biolink:NamedThing	manchette assembly	The aggregation, arrangement and bonding together of a set of components to form a manchette.	tmpzr1t_l9r_go_relaxed.owl	manchette formation							krc	2016-05-12T15:19:08Z					biological_process											owl:Class	
GO:0046538	biolink:NamedThing	2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity	Catalysis of the reaction: 2-phospho-D-glycerate = 3-phospho-D-glycerate; this reaction requires the cofactor 2,3-bisphosphoglycerate.	tmpzr1t_l9r_go_relaxed.owl	glycerate phosphomutase (diphosphoglycerate cofactor) activity|PGAM-d													molecular_function											owl:Class	
GO:0004619	biolink:NamedThing	phosphoglycerate mutase activity	Catalysis of the reaction: 2-phospho-D-glycerate = 3-phospho-D-glycerate.	tmpzr1t_l9r_go_relaxed.owl	monophosphoglycerate mutase activity|diphosphoglycomutase|PGAM activity|MPGM|phosphoglycerate phosphomutase activity|phosphoglyceromutase activity|PGM|PGA mutase activity|GriP mutase|monophosphoglyceromutase activity|bisphosphoglyceromutase|D-phosphoglycerate 2,3-phosphomutase activity				EC:5.4.2.1|Reactome:R-HSA-71654|RHEA:15901|MetaCyc:3PGAREARR-RXN|Reactome:R-HSA-71445									molecular_function											owl:Class	
GO:1901592	biolink:NamedThing	negative regulation of double-strand break repair via break-induced replication	Any process that stops, prevents or reduces the frequency, rate or extent of double-strand break repair via break-induced replication.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of double-strand break repair via break-induced replication|downregulation of double-strand break repair via break-induced replication|inhibition of double-strand break repair via break-induced replication|down regulation of double-strand break repair via break-induced replication							al	2012-11-07T16:37:39Z					biological_process											owl:Class	
GO:0097471	biolink:NamedThing	mossy fiber rosette	A synapse of a mossy fiber onto the dendrite of a granule cell; each mossy fiber can have up to 50 rosettes.	tmpzr1t_l9r_go_relaxed.owl	cerebellar mossy fiber to granule cell synapse				NIF_Subcellular:nlx_subcell_091021			pr	2013-02-21T07:42:52Z					cellular_component											owl:Class	
GO:2000972	biolink:NamedThing	positive regulation of detection of glucose	Any process that activates or increases the frequency, rate or extent of detection of glucose.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of glucose perception|positive regulation of glucose detection|positive regulation of glucose sensing							vk	2011-08-02T10:18:56Z					biological_process											owl:Class	
GO:1901230	biolink:NamedThing	negative regulation of non-canonical Wnt signaling pathway via JNK cascade	Any process that stops, prevents or reduces the frequency, rate or extent of non-canonical Wnt signaling pathway via JNK cascade.	tmpzr1t_l9r_go_relaxed.owl	inhibition of non-canonical Wnt receptor signaling pathway via JNK cascade|negative regulation of non-canonical Wnt-activated signaling pathway via JNK cascade|down-regulation of non-canonical Wnt receptor signalling pathway via JNK cascade|downregulation of non-canonical Wnt receptor signalling pathway via JNK cascade|down-regulation of non-canonical Wnt receptor signaling pathway via JNK cascade|negative regulation of non-canonical Wnt receptor signaling pathway via JNK cascade|inhibition of non-canonical Wnt receptor signalling pathway via JNK cascade|downregulation of non-canonical Wnt receptor signaling pathway via JNK cascade|down regulation of non-canonical Wnt receptor signaling pathway via JNK cascade|negative regulation of non-canonical Wnt receptor signalling pathway via JNK cascade|down regulation of non-canonical Wnt receptor signalling pathway via JNK cascade							vk	2012-08-07T14:14:39Z					biological_process											owl:Class	
GO:0060552	biolink:NamedThing	positive regulation of fructose 1,6-bisphosphate metabolic process	Any process that increases the rate, frequency or extent of fructose 1,6-bisphosphate metabolism. Fructose 1,6-bisphosphate metabolism is the chemical reactions and pathways involving fructose 1,6-bisphosphate, also known as FBP. The D enantiomer is a metabolic intermediate in glycolysis and gluconeogenesis.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-04-13T02:23:40Z					biological_process											owl:Class	
GO:0043048	biolink:NamedThing	dolichyl monophosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of dolichyl diphosphate, a phosphorylated dolichol derivative.	tmpzr1t_l9r_go_relaxed.owl	dolichyl monophosphate formation|dolichyl monophosphate synthesis|dolichyl monophosphate anabolism|dolichyl monophosphate biosynthesis													biological_process											owl:Class	
GO:0102601	biolink:NamedThing	cytochrome P450 dependent beta-amyrin 16beta-hydroxylase activity	Catalysis of the reaction: beta-amyrin + O2 + H+ + NADPH = 16beta-hydroxy-beta-amyrin + H2O + NADP.	tmpzr1t_l9r_go_relaxed.owl					RHEA:55440|EC:1.14.14.63|MetaCyc:RXN-15385									molecular_function											owl:Class	
GO:1902383	biolink:NamedThing	11-oxo-beta-amyrin biosynthetic process	The chemical reactions and pathways resulting in the formation of 11-oxo-beta-amyrin.	tmpzr1t_l9r_go_relaxed.owl	11-oxo-beta-amyrin biosynthesis|11-oxo-beta-amyrin synthesis|11-oxo-beta-amyrin formation|11-oxo-beta-amyrin anabolism							ms	2013-09-03T12:55:46Z					biological_process											owl:Class	
GO:1902381	biolink:NamedThing	11-oxo-beta-amyrin metabolic process	The chemical reactions and pathways involving 11-oxo-beta-amyrin.	tmpzr1t_l9r_go_relaxed.owl	11-oxo-beta-amyrin metabolism							ms	2013-09-03T12:55:29Z					biological_process											owl:Class	
GO:0046158	biolink:NamedThing	ocellus pigment metabolic process	The chemical reactions and pathways involving ocellus pigments, any general or particular coloring matter in living organisms, found or utilized in the ocellus, a minute simple eye found in many invertebrates.	tmpzr1t_l9r_go_relaxed.owl	ocellus pigment metabolism													biological_process											owl:Class	
GO:0002865	biolink:NamedThing	negative regulation of acute inflammatory response to antigenic stimulus	Any process that stops, prevents, or reduces the frequency, rate, or extent of an acute inflammatory response to an antigenic stimulus.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of acute inflammatory response to antigenic stimulus|inhibition of acute inflammatory response to antigenic stimulus|downregulation of acute inflammatory response to antigenic stimulus|down regulation of acute inflammatory response to antigenic stimulus													biological_process											owl:Class	
GO:0002864	biolink:NamedThing	regulation of acute inflammatory response to antigenic stimulus	Any process that modulates the frequency, rate, or extent of an acute inflammatory response to an antigenic stimulus.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0018962	biolink:NamedThing	3-phenylpropionate metabolic process	The chemical reactions and pathways involving 3-phenylpropionate, the anion of phenylpropanoic acid. It is produced from putrefaction of proteins in soil or breakdown of several constituents of plants, such as lignin, various oils and resins.	tmpzr1t_l9r_go_relaxed.owl	hydrocinnamic acid metabolic process|hydrocinnamic acid metabolism|phenylpropanoate metabolic process|phenylpropanoate metabolism|3-phenylpropionate metabolism				UM-BBD_pathwayID:ppa									biological_process											owl:Class	
GO:0005687	biolink:NamedThing	U4 snRNP	A ribonucleoprotein complex that contains small nuclear RNA U4, a heptameric ring of Sm proteins, as well as several proteins that are unique to the U4 snRNP, most of which remain associated with the U4 snRNA both while the U4 snRNP is free or assembled into the U4/U6 snRNP or into a series of spliceosomal complexes.	tmpzr1t_l9r_go_relaxed.owl	snRNP U4													cellular_component											owl:Class	
GO:0033863	biolink:NamedThing	ribose 1,5-bisphosphate phosphokinase activity	Catalysis of the reaction: D-ribose 1,5-diphosphate + ATP = 5-phospho-alpha-D-ribose 1-diphosphate + ADP + H(+).	tmpzr1t_l9r_go_relaxed.owl	PhnN|ribose 1,5-bisphosphokinase activity|ATP:ribose-1,5-bisphosphate phosphotransferase activity				MetaCyc:2.7.4.23-RXN|KEGG_REACTION:R06836|EC:2.7.4.23|RHEA:20109									molecular_function											owl:Class	
GO:1903908	biolink:NamedThing	positive regulation of plasma membrane raft polarization	Any process that activates or increases the frequency, rate or extent of plasma membrane raft polarization.	tmpzr1t_l9r_go_relaxed.owl	activation of plasma membrane raft polarization|up-regulation of plasma membrane raft polarization|up regulation of plasma membrane raft polarization|upregulation of plasma membrane raft polarization							als	2015-02-09T10:54:15Z					biological_process											owl:Class	
GO:1902124	biolink:NamedThing	(+)-pinoresinol metabolic process	The chemical reactions and pathways involving (+)-pinoresinol.	tmpzr1t_l9r_go_relaxed.owl	(+)-pinoresinol metabolism							ms	2013-05-21T08:49:10Z					biological_process											owl:Class	
GO:0008509	biolink:NamedThing	anion transmembrane transporter activity	Enables the transfer of a negatively charged ion from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	anion transporter activity				Reactome:R-HSA-166214									molecular_function											owl:Class	
GO:0102628	biolink:NamedThing	costunolide 3beta-hydroxylase activity	Catalysis of the reaction: costunolide + NADPH + O2 + H+ <=> 3beta-hydroxycostunolide + NADP + H2O.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-15533									molecular_function											owl:Class	
GO:1900605	biolink:NamedThing	tensidol A biosynthetic process	The chemical reactions and pathways resulting in the formation of tensidol A.	tmpzr1t_l9r_go_relaxed.owl	tensidol A biosynthesis|tensidol A synthesis|tensidol A anabolism|tensidol A formation							di	2012-05-15T06:58:16Z					biological_process											owl:Class	
GO:1905952	biolink:NamedThing	regulation of lipid localization	Any process that modulates the frequency, rate or extent of lipid localization.	tmpzr1t_l9r_go_relaxed.owl	regulation of lipid localisation							rz	2017-02-21T12:12:22Z					biological_process											owl:Class	
GO:0034482	biolink:NamedThing	chondroitin 2-O-sulfotransferase activity	Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + chondroitin = adenosine 3',5'-bisphosphate + chondroitin 2'-O-sulfate. Results in sulfation of glucuronic acid and iduronic acid residues.	tmpzr1t_l9r_go_relaxed.owl	chondroitin 2-O-sulphotransferase activity|chondroitin 2-sulfotransferase activity													molecular_function											owl:Class	
GO:0034481	biolink:NamedThing	chondroitin sulfotransferase activity	Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + chondroitin = adenosine 3',5'-bisphosphate + chondroitin sulfate.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1904658	biolink:NamedThing	positive regulation of sensory perception of sweet taste	Any process that activates or increases the frequency, rate or extent of sensory perception of sweet taste.	tmpzr1t_l9r_go_relaxed.owl	up regulation of sensory perception of sweet taste|positive regulation of sweet taste perception|upregulation of sweet taste perception|up-regulation of sensory perception of sweet taste|activation of sensory perception of sweet taste|up regulation of sweet taste perception|activation of sweet taste perception|up-regulation of sweet taste perception|upregulation of sensory perception of sweet taste							mr	2015-09-04T16:43:24Z					biological_process											owl:Class	
GO:1904656	biolink:NamedThing	regulation of sensory perception of sweet taste	Any process that modulates the frequency, rate or extent of sensory perception of sweet taste.	tmpzr1t_l9r_go_relaxed.owl	regulation of sweet taste perception							mr	2015-09-04T16:43:12Z					biological_process											owl:Class	
GO:0006308	biolink:NamedThing	DNA catabolic process	The cellular DNA metabolic process resulting in the breakdown of DNA, deoxyribonucleic acid, one of the two main types of nucleic acid, consisting of a long unbranched macromolecule formed from one or two strands of linked deoxyribonucleotides, the 3'-phosphate group of each constituent deoxyribonucleotide being joined in 3',5'-phosphodiester linkage to the 5'-hydroxyl group of the deoxyribose moiety of the next one.	tmpzr1t_l9r_go_relaxed.owl	DNA breakdown|DNA degradation|DNA catabolism													biological_process											owl:Class	
GO:1904943	biolink:NamedThing	negative regulation of cardiac ventricle formation	Any process that stops, prevents or reduces the frequency, rate or extent of cardiac ventricle formation.	tmpzr1t_l9r_go_relaxed.owl	inhibition of cardiac ventricle formation|down regulation of cardiac ventricle formation|down-regulation of cardiac ventricle formation|downregulation of cardiac ventricle formation							bc	2016-02-02T16:37:24Z					biological_process											owl:Class	
GO:1901211	biolink:NamedThing	negative regulation of cardiac chamber formation	Any process that stops, prevents or reduces the frequency, rate or extent of cardiac chamber formation.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of cardiac chamber formation|down regulation of heart chamber formation|inhibition of heart chamber formation|downregulation of heart chamber formation|inhibition of cardiac chamber formation|negative regulation of heart chamber formation|downregulation of cardiac chamber formation|down-regulation of heart chamber formation|down regulation of cardiac chamber formation							rl	2012-07-31T07:18:57Z					biological_process											owl:Class	
GO:0071636	biolink:NamedThing	positive regulation of transforming growth factor beta production	Any process that activates or increases the frequency, rate, or extent of production of transforming growth factor-beta.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of TGF-B production|positive regulation of transforming growth factor-beta production|positive regulation of TGFbeta production|positive regulation of TGFB production|positive regulation of transforming growth factor-beta secretion|positive regulation of TGF-beta production							mah	2010-02-12T10:39:51Z			GO:2001203		biological_process											owl:Class	
GO:0140703	biolink:NamedThing	3',3'-cyclic GMP-AMP binding	Binding to 3',3' cyclic GMP-AMP (cGAMP) nucleotide, a cyclic purine dinucleotide that consists of AMP and GMP units cyclized via 3',5' and 3',5' linkages.	tmpzr1t_l9r_go_relaxed.owl	3',3'-cGMP-AMP binding|3',3' cyclic-GMP-AMP binding|3',3'-cyclic GAMP binding|3',3'-cGAMP binding	https://github.com/geneontology/go-ontology/issues/21980						pg	2021-08-27T05:44:15Z					molecular_function											owl:Class	
GO:0090134	biolink:NamedThing	cell migration involved in mesendoderm migration	The orderly movement of epithelial cells from one site to another that contributes to the migration of mesendodermal tissue.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-12-07T03:28:11Z					biological_process											owl:Class	
GO:0002067	biolink:NamedThing	glandular epithelial cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a glandular epithelial cell. A glandular epithelial cell is a columnar/cuboidal epithelial cell found in a two dimensional sheet with a free surface exposed to the lumen of a gland.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0043551	biolink:NamedThing	regulation of phosphatidylinositol 3-kinase activity	Any process that modulates the frequency, rate or extent of phosphatidylinositol 3-kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to an inositol lipid at the 3' position of the inositol ring.	tmpzr1t_l9r_go_relaxed.owl	regulation of phosphoinositide 3-kinase activity													biological_process											owl:Class	
GO:0015990	biolink:NamedThing	electron transport coupled proton transport	The transport of protons against an electrochemical gradient, using energy from electron transport.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0015988	biolink:NamedThing	energy coupled proton transmembrane transport, against electrochemical gradient	The transport of protons across a membrane and against an electrochemical gradient, using energy from a source such as ATP hydrolysis, light, or electron transport.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0009101	biolink:NamedThing	glycoprotein biosynthetic process	The chemical reactions and pathways resulting in the formation of glycoproteins, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide.	tmpzr1t_l9r_go_relaxed.owl	glycoprotein anabolism|glycoprotein formation|glycoprotein synthesis|glycoprotein biosynthesis													biological_process											owl:Class	
GO:0090167	biolink:NamedThing	Golgi distribution to daughter cells	Any process in which disassembled Golgi vesicles are localized into daughter cells upon cell division.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-12-08T09:15:11Z					biological_process											owl:Class	
GO:0060255	biolink:NamedThing	regulation of macromolecule metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0044313	biolink:NamedThing	protein K6-linked deubiquitination	A protein deubiquitination process in which a K6-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 6 of the ubiquitin monomers, is removed from a protein.	tmpzr1t_l9r_go_relaxed.owl								jl	2010-06-01T03:10:11Z					biological_process											owl:Class	
GO:0002632	biolink:NamedThing	negative regulation of granuloma formation	Any process that stops, prevents, or reduces the frequency, rate, or extent of granuloma formation.	tmpzr1t_l9r_go_relaxed.owl	downregulation of granuloma formation|down-regulation of granuloma formation|inhibition of granuloma formation|down regulation of granuloma formation													biological_process											owl:Class	
GO:0002677	biolink:NamedThing	negative regulation of chronic inflammatory response	Any process that stops, prevents, or reduces the frequency, rate, or extent of a chronic inflammatory response.	tmpzr1t_l9r_go_relaxed.owl	downregulation of chronic inflammatory response|down-regulation of chronic inflammatory response|inhibition of chronic inflammatory response|down regulation of chronic inflammatory response													biological_process											owl:Class	
GO:0016979	biolink:NamedThing	lipoate-protein ligase activity	Catalysis of the lipoylation of a protein in two steps: ATP + (R)-lipoate + a [lipoyl-carrier protein]-L-lysine = a [lipoyl-carrier protein]-N6-(lipoyl)lysine + AMP + diphosphate (overall reaction): (1) ATP + (R)-lipoate = lipoyl-AMP + diphosphate; (2) lipoyl-AMP + a [lipoyl-carrier protein]-L-lysine = a [lipoyl-carrier protein]-N6-(lipoyl)lysine + AMP.	tmpzr1t_l9r_go_relaxed.owl	lipoate-protein ligase A activity|lipoate-protein ligase B activity|lipoate-protein ligase activity (lipoylation of glycine cleavage complex)				MetaCyc:RXN-13039|MetaCyc:RXN-8654|MetaCyc:RXN0-1141|EC:6.3.1.20|RHEA:49288|MetaCyc:RXN-8655							GO:0102315|GO:0016978|GO:0008916		molecular_function											owl:Class	
GO:0050646	biolink:NamedThing	5-oxo-6E,8Z,11Z,14Z-icosatetraenoic acid binding	Binding to 5-oxo-6E,8Z,11Z,14Z-icosatetraenoic acid, a straight-chain fatty acid with twenty carbon atoms and four double bonds.	tmpzr1t_l9r_go_relaxed.owl	5-oxo-6E,8Z,11Z,14Z-eicosatetraenoic acid binding													molecular_function											owl:Class	
GO:0062099	biolink:NamedThing	negative regulation of programmed necrotic cell death	Any process that decreases the frequency, rate or extent of programmed necrotic cell death.	tmpzr1t_l9r_go_relaxed.owl								dph	2018-11-29T15:05:56Z					biological_process											owl:Class	
GO:0062098	biolink:NamedThing	regulation of programmed necrotic cell death	Any process that modulates the frequency, rate or extent of programmed necrotic cell death.	tmpzr1t_l9r_go_relaxed.owl								dph	2018-11-29T14:58:26Z					biological_process											owl:Class	
GO:0003343	biolink:NamedThing	septum transversum development	The progression of the septum transversum from its initial formation to the mature structure. The septum transversum is a portion of the trunk mesenchyme.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-12-01T10:40:17Z					biological_process											owl:Class	
GO:2000320	biolink:NamedThing	negative regulation of T-helper 17 cell differentiation	Any process that stops, prevents or reduces the frequency, rate or extent of T-helper 17 cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of T-helper 17 cell development							mah	2011-01-18T01:44:31Z					biological_process											owl:Class	
GO:0044092	biolink:NamedThing	negative regulation of molecular function	Any process that stops or reduces the rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding.	tmpzr1t_l9r_go_relaxed.owl								jl	2009-04-21T04:07:27Z					biological_process											owl:Class	
GO:0047915	biolink:NamedThing	ganglioside galactosyltransferase activity	Catalysis of the reaction: UDP-galactose + N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-1,4-beta-D-glucosyl-N-acylsphingosine = UDP + D-galactosyl-1,3-beta-N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosyl-N-acylsphingosine.	tmpzr1t_l9r_go_relaxed.owl	UDP-galactose-GM2 galactosyltransferase activity|GM1-synthase activity|UDP-galactose:N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosyl-N-acylsphingosine beta-1,3-D-galactosyltransferase activity|uridine diphosphate D-galactose:glycolipid galactosyltransferase activity|UDP-galactose-GM2 ganglioside galactosyltransferase activity|UDP galactose-LAC Tet-ceramide alpha-galactosyltransferase activity|UDPgalactose-ceramide galactosyltransferase activity|uridine diphosphogalactose-GM2 galactosyltransferase activity|uridine diphosphogalactose-ceramide galactosyltransferase activity|UDPgalactose:N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosyl-N-acylsphingosine beta-1,3-D-galactosyltransferase activity|UDP-galactose:N-acetylgalactosaminyl-(N-acetylneuraminyl) galactosyl-glucosyl-ceramide galactosyltransferase activity				MetaCyc:GANGLIOSIDE-GALACTOSYLTRANSFERASE-RXN|EC:2.4.1.62|RHEA:16773									molecular_function											owl:Class	
GO:0004972	biolink:NamedThing	NMDA glutamate receptor activity	An cation channel that opens in response to binding by extracellular glutmate, but only if glycine is also bound and the membrane is depolarized.  Voltage gating is indirect, due to ejection of bound magnesium from the pore at permissive voltages.	tmpzr1t_l9r_go_relaxed.owl	NMDA receptor|N-methyl-D-aspartate selective glutamate receptor activity				Wikipedia:NMDA_receptor	The name of this receptor comes from its selective activation by N-methyl-D-aspartate (NMDA). Note that this term represents an activity and not a gene product.								molecular_function											owl:Class	
GO:2001000	biolink:NamedThing	regulation of xylan catabolic process	Any process that modulates the frequency, rate or extent of xylan catabolic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of xylan breakdown|regulation of xylan catabolism|regulation of xylan degradation							tt	2011-08-08T03:23:13Z					biological_process											owl:Class	
GO:1904417	biolink:NamedThing	positive regulation of xenophagy	Any process that activates or increases the frequency, rate or extent of xenophagy.	tmpzr1t_l9r_go_relaxed.owl	up regulation of xenophagy|up-regulation of xenophagy|upregulation of xenophagy|activation of xenophagy					An example of this is mouse Tbk1 (UniProt symbol, Q9WUN2) in PMID:21617041 (inferred from mutant phenotype).		pad	2015-06-29T12:30:59Z					biological_process											owl:Class	
GO:0001744	biolink:NamedThing	insect visual primordium formation	Establishment of the optic lobe placode. In Drosophila, for example, the placode appears in the dorsolateral region of the head in late stage 11 embryos and is the precursor to the larval visual system.	tmpzr1t_l9r_go_relaxed.owl	optic lobe and Bolwig's organ precursor formation|optic lobe placode formation											GO:0007457		biological_process											owl:Class	
GO:1990010	biolink:NamedThing	compound eye retinal cell apoptotic process	Any apoptotic process in a compound eye retinal cell.	tmpzr1t_l9r_go_relaxed.owl								pr	2012-12-12T10:21:07Z					biological_process											owl:Class	
GO:1990009	biolink:NamedThing	retinal cell apoptotic process	Any apoptotic process in a retinal cell.	tmpzr1t_l9r_go_relaxed.owl	induction of retinal programmed cell death							pr	2012-12-12T10:15:08Z			GO:0046674		biological_process											owl:Class	
GO:0031737	biolink:NamedThing	CX3C chemokine receptor binding	Binding to a CX3C chemokine receptor.	tmpzr1t_l9r_go_relaxed.owl	fractalkine receptor binding|CX3C chemokine receptor ligand													molecular_function											owl:Class	
GO:0042379	biolink:NamedThing	chemokine receptor binding	Binding to a chemokine receptor.	tmpzr1t_l9r_go_relaxed.owl	chemokine receptor ligand													molecular_function											owl:Class	
GO:0032562	biolink:NamedThing	dAMP binding	Binding to dAMP, deoxyadenosine monophosphate.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0032558	biolink:NamedThing	adenyl deoxyribonucleotide binding	Binding to an adenyl deoxyribonucleotide, any compound consisting of adenosine esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the deoxyribose moiety.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0048830	biolink:NamedThing	adventitious root development	The process whose specific outcome is the progression of adventitious root over time, from its formation to the mature structure. Adventitious roots are post-embryonic roots that develop from the plant shoot.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0048364	biolink:NamedThing	root development	The process whose specific outcome is the progression of the root over time, from its formation to the mature structure. The root is the water- and mineral-absorbing part of a plant which is usually underground, does not bear leaves, tends to grow downwards and is typically derived from the radicle of the embryo.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0062127	biolink:NamedThing	fatty acid primary amide catabolic process	The chemical reactions and pathways resulting in the breakdown of primary fatty amides.	tmpzr1t_l9r_go_relaxed.owl	primary fatty amide catabolic process							dph	2019-05-30T18:26:49Z					biological_process											owl:Class	
GO:0035768	biolink:NamedThing	endothelial cell chemotaxis to fibroblast growth factor	The directed movement of an endothelial cell in response to the presence of fibroblast growth factor (FGF).	tmpzr1t_l9r_go_relaxed.owl								bf	2011-03-31T04:32:17Z					biological_process											owl:Class	
GO:0035766	biolink:NamedThing	cell chemotaxis to fibroblast growth factor	The directed movement of a motile cell in response to the presence of fibroblast growth factor (FGF).	tmpzr1t_l9r_go_relaxed.owl								bf	2011-03-31T04:30:16Z					biological_process											owl:Class	
GO:0039580	biolink:NamedThing	suppression by virus of host PKR signaling	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host PKR (Protein Kinase regulated by RNA) signaling. Host PKR signaling includes targets such as the translation initiation factor eIF2alpha,  inhibiting protein synthesis as an antiviral response.	tmpzr1t_l9r_go_relaxed.owl	suppression by virus of host EIF2AK2 activity|suppression by virus of host PKR activity	https://github.com/geneontology/go-ontology/issues/21971						bf						biological_process											owl:Class	
GO:0019606	biolink:NamedThing	2-oxobutyrate catabolic process	The chemical reactions and pathways resulting in the breakdown of 2-oxobutyrate, the anion of the organic acid 2-oxobutyric acid, which contains a ketone group on carbon 2.	tmpzr1t_l9r_go_relaxed.owl	2-oxobutyrate degradation|2-oxobutyrate catabolism|alpha-ketobutyrate catabolic process|2-oxobutyrate breakdown|alpha-ketobutyrate catabolism				MetaCyc:2OXOBUTYRATECAT-PWY									biological_process											owl:Class	
GO:0019626	biolink:NamedThing	short-chain fatty acid catabolic process	The chemical reactions and pathways resulting in the breakdown of fatty acids with a chain length of less than C6.	tmpzr1t_l9r_go_relaxed.owl	short-chain fatty acid degradation|short-chain fatty acid catabolism|short-chain fatty acid breakdown				MetaCyc:ACETOACETATE-DEG-PWY									biological_process											owl:Class	
GO:0071333	biolink:NamedThing	cellular response to glucose stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucose stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-12-10T05:38:03Z					biological_process											owl:Class	
GO:1900506	biolink:NamedThing	regulation of iron-sulfur-molybdenum cofactor assembly	Any process that modulates the frequency, rate or extent of iron-sulfur-molybdenum cofactor assembly.	tmpzr1t_l9r_go_relaxed.owl	regulation of FeMoco assembly|regulation of iron molybdenum cofactor biosynthetic process|regulation of iron molybdenum cofactor assembly|regulation of FeMoco biosynthetic process|regulation of iron molybdenum cofactor biosynthesis							tt	2012-05-02T04:02:16Z					biological_process											owl:Class	
GO:0033156	biolink:NamedThing	oligogalacturonide transport	The directed movement of oligogalacturonides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0034343	biolink:NamedThing	type III interferon production	The appearance of type III interferon due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Interferon lambda is the only member of the type III interferon found so far.	tmpzr1t_l9r_go_relaxed.owl	type III interferon secretion|type III IFN production					Note that IL-28A, IL-28B, and IL-29 are types of interferon-lambda. This term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.						GO:0072644		biological_process											owl:Class	
GO:0044865	biolink:NamedThing	negative regulation by virus of host cell division	Any process where an infecting virus stops, prevents, or reduces the frequency, rate or extent of its host's cell division.	tmpzr1t_l9r_go_relaxed.owl	inhibition by virus of host cell division							jl	2014-08-05T16:31:44Z					biological_process											owl:Class	
GO:0004516	biolink:NamedThing	nicotinate phosphoribosyltransferase activity	Catalysis of the reaction: diphosphate + nicotinate D-ribonucleotide = 5-phospho-alpha-D-ribose 1-diphosphate + H(+) + nicotinate.	tmpzr1t_l9r_go_relaxed.owl	niacin ribonucleotidase activity|nicotinate-nucleotide:diphosphate phospho-alpha-D-ribosyltransferase activity|nicotinic acid mononucleotide pyrophosphorylase activity|nicotinic acid mononucleotide glycohydrolase activity|nicotinic acid phosphoribosyltransferase activity				EC:6.3.4.21|KEGG_REACTION:R01724|MetaCyc:NICOTINATEPRIBOSYLTRANS-RXN|Reactome:R-HSA-197186|RHEA:36163									molecular_function											owl:Class	
GO:0080088	biolink:NamedThing	spermidine hydroxycinnamate conjugate biosynthetic process	The chemical reactions and pathways resulting in the formation of spermidine hydroxycinnamate conjugates.	tmpzr1t_l9r_go_relaxed.owl								dhl	2009-04-22T03:24:03Z					biological_process											owl:Class	
GO:1901334	biolink:NamedThing	lactone metabolic process	The chemical reactions and pathways involving lactone.	tmpzr1t_l9r_go_relaxed.owl	lactone metabolism							bf	2012-09-03T10:26:00Z					biological_process											owl:Class	
GO:0052825	biolink:NamedThing	inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity	Catalysis of the reaction: inositol-1,3,4,5,6-pentakisphosphate + H2O = inositol-3,4,5,6-tetrakisphosphate + phosphate.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-1855219				2011-11-29T09:49:22Z					molecular_function											owl:Class	
GO:1902474	biolink:NamedThing	positive regulation of protein localization to synapse	Any process that activates or increases the frequency, rate or extent of protein localization to synapse.	tmpzr1t_l9r_go_relaxed.owl	activation of protein localisation to synapse|up-regulation of protein localisation to synapse|up regulation of protein localization to synapse|positive regulation of protein localisation to synapse|upregulation of protein localisation to synapse|upregulation of protein localization to synapse|activation of protein localization to synapse|up-regulation of protein localization to synapse|up regulation of protein localisation to synapse							kmv	2013-10-25T15:09:18Z					biological_process											owl:Class	
GO:1902473	biolink:NamedThing	regulation of protein localization to synapse	Any process that modulates the frequency, rate or extent of protein localization to synapse.	tmpzr1t_l9r_go_relaxed.owl	regulation of protein localisation to synapse							kmv	2013-10-25T15:09:09Z					biological_process											owl:Class	
GO:1904253	biolink:NamedThing	positive regulation of bile acid metabolic process	Any process that activates or increases the frequency, rate or extent of bile acid metabolic process.	tmpzr1t_l9r_go_relaxed.owl	activation of bile acid metabolism|up regulation of bile acid metabolic process|up-regulation of bile acid metabolism|activation of bile acid metabolic process|up-regulation of bile acid metabolic process|upregulation of bile acid metabolic process|up regulation of bile acid metabolism|positive regulation of bile acid metabolism|upregulation of bile acid metabolism							bf	2015-05-20T11:04:40Z					biological_process											owl:Class	
GO:0032063	biolink:NamedThing	negative regulation of translational initiation in response to osmotic stress	Any process that stops, prevents or reduces the rate of translation initiation, as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell.	tmpzr1t_l9r_go_relaxed.owl	downregulation of translation initiation in response to osmotic stress|inhibition of translation initiation in response to osmotic stress|down-regulation of translation initiation in response to osmotic stress|down regulation of translation initiation in response to osmotic stress													biological_process											owl:Class	
GO:0070761	biolink:NamedThing	pre-snoRNP complex	A ribonucleoprotein complex that contains a precursor small nucleolar RNA (pre-snoRNA) and associated proteins, and forms during small nucleolar ribonucleoprotein complex (snoRNP) assembly. Pre-snoRNP complexes may contain proteins not found in the corresponding mature snoRNP complexes.	tmpzr1t_l9r_go_relaxed.owl	pre-small nucleolar ribonucleoprotein complex							mah	2009-06-23T02:32:10Z					cellular_component											owl:Class	
GO:0097347	biolink:NamedThing	TAM protein secretion complex	A heterooligomeric protein complex that spans the bacterial periplasm and enables the secretion of adhesin proteins in Gram-negative bacteria. In Citrobacter rodentium, Salmonella enterica and Escherichia coli, the TAM complex consists of an Omp85-family protein, TamA, in the outer membrane and TamB in the inner membrane.	tmpzr1t_l9r_go_relaxed.owl	translocation and assembly module protein complex							pr	2012-06-21T10:44:15Z					cellular_component											owl:Class	
GO:0010983	biolink:NamedThing	positive regulation of high-density lipoprotein particle clearance	Any process that increases the rate, frequency or extent of high-density lipoprotein particle clearance. High-density lipoprotein particle clearance is the process in which a high-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-06-01T12:03:32Z					biological_process											owl:Class	
GO:0010982	biolink:NamedThing	regulation of high-density lipoprotein particle clearance	Any process that modulates the rate, frequency or extent of high-density lipoprotein particle clearance. High-density lipoprotein particle clearance is the process in which a high-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-06-01T12:01:30Z					biological_process											owl:Class	
GO:0048022	biolink:NamedThing	negative regulation of melanin biosynthetic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of melanin.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of melanin formation|inhibition of melanin biosynthetic process|negative regulation of melanin anabolism|downregulation of melanin biosynthetic process|negative regulation of melanin synthesis|down-regulation of melanin biosynthetic process|down regulation of melanin biosynthetic process|negative regulation of melanin biosynthesis													biological_process											owl:Class	
GO:0051546	biolink:NamedThing	keratinocyte migration	The directed movement of a keratinocyte, epidermal cells which synthesize keratin, from one site to another.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0003838	biolink:NamedThing	sterol 24-C-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + 5-alpha-cholest-8,24-dien-3-beta-ol = S-adenosyl-L-homocysteine + 24-methylene-5-alpha-cholest-8-en-3-beta-ol.	tmpzr1t_l9r_go_relaxed.owl	S-adenosyl-L-methionine:Delta24(23)-sterol methyltransferase activity|delta(24)-sterol C-methyltransferase activity|delta24-sterol methyltransferase activity|S-adenosyl-4-methionine:sterol Delta(24)-methyltransferase activity|sterol 24C methyltransferase activity|delta(24)-methyltransferase activity|zymosterol-24-methyltransferase activity|delta24-methyltransferase activity|SMT1 activity|S-adenosyl-L-methionine:zymosterol 24-C-methyltransferase activity|24-sterol C-methyltransferase activity|delta(24)-sterol methyltransferase activity|phytosterol methyltransferase activity|S-adenosyl-L-methionine:Delta(24(23))-sterol methyltransferase activity|S-adenosyl-4-methionine:sterol delta24-methyltransferase activity	https://github.com/geneontology/go-ontology/issues/20399			MetaCyc:RXN3O-178|RHEA:21128|MetaCyc:RXN-11201|EC:2.1.1.41							GO:0102101		molecular_function											owl:Class	
GO:0010821	biolink:NamedThing	regulation of mitochondrion organization	Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a mitochondrion.	tmpzr1t_l9r_go_relaxed.owl	regulation of mitochondrion organisation													biological_process											owl:Class	
GO:1904873	biolink:NamedThing	negative regulation of telomerase RNA localization to Cajal body	Any process that stops, prevents or reduces the frequency, rate or extent of telomerase RNA localization to Cajal body.	tmpzr1t_l9r_go_relaxed.owl	inhibition of telomerase RNA localization to Cajal body|down-regulation of telomerase RNA localization to Cajal body|down regulation of telomerase RNA localization to Cajal body|downregulation of telomerase RNA localization to Cajal body							nc	2015-12-18T11:28:27Z					biological_process											owl:Class	
GO:0044242	biolink:NamedThing	cellular lipid catabolic process	The chemical reactions and pathways resulting in the breakdown of lipids, as carried out by individual cells.	tmpzr1t_l9r_go_relaxed.owl	cellular lipid degradation|cellular lipid catabolism|cellular lipid breakdown													biological_process											owl:Class	
GO:0031771	biolink:NamedThing	type 1 hypocretin receptor binding	Binding to a type 1 hypocretin receptor.	tmpzr1t_l9r_go_relaxed.owl	type 1 hypocretin receptor ligand|type 1 orexin receptor binding													molecular_function											owl:Class	
GO:0042324	biolink:NamedThing	hypocretin receptor binding	Binding to a hypocretin receptor.	tmpzr1t_l9r_go_relaxed.owl	hypocretin receptor ligand|orexin receptor ligand|orexin receptor binding													molecular_function											owl:Class	
GO:1900158	biolink:NamedThing	negative regulation of bone mineralization involved in bone maturation	Any process that stops, prevents or reduces the frequency, rate or extent of bone mineralization involved in bone maturation.	tmpzr1t_l9r_go_relaxed.owl	inhibition of bone mineralization involved in bone maturation|down regulation of bone mineralization involved in bone maturation|downregulation of bone mineralization involved in bone maturation|down-regulation of bone mineralization involved in bone maturation							vk	2012-03-07T08:55:12Z					biological_process											owl:Class	
GO:1902726	biolink:NamedThing	positive regulation of skeletal muscle satellite cell differentiation	Any process that activates or increases the frequency, rate or extent of satellite cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	upregulation of satellite cell differentiation|up-regulation of satellite cell differentiation|up regulation of satellite cell differentiation|activation of satellite cell differentiation							mr	2014-02-24T16:10:14Z					biological_process											owl:Class	
GO:2001016	biolink:NamedThing	positive regulation of skeletal muscle cell differentiation	Any process that activates or increases the frequency, rate or extent of skeletal muscle cell differentiation.	tmpzr1t_l9r_go_relaxed.owl								yaf	2011-08-11T08:54:44Z					biological_process											owl:Class	
GO:0009696	biolink:NamedThing	salicylic acid metabolic process	The chemical reactions and pathways involving of salicylic acid (2-hydroxybenzoic acid), a derivative of benzoic acid.	tmpzr1t_l9r_go_relaxed.owl	salicylic acid metabolism													biological_process											owl:Class	
GO:0102614	biolink:NamedThing	germacrene A acid 8beta-hydroxylase activity	Catalysis of the reaction: germacra-1(10),4,11(13)-trien-12-oate + NADPH + O2 + H+ <=> 8beta-hydroxy-germacra-1(10),4,11(13)-trien-12-oate + NADP + H2O.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-15460									molecular_function											owl:Class	
GO:1905923	biolink:NamedThing	positive regulation of acetylcholine biosynthetic process	Any process that activates or increases the frequency, rate or extent of acetylcholine biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of acetylcholine synthesis|up-regulation of acetylcholine anabolism|up-regulation of acetylcholine biosynthetic process|positive regulation of acetylcholine anabolism|upregulation of acetylcholine synthesis|activation of acetylcholine biosynthetic process|positive regulation of acetylcholine formation|up regulation of acetylcholine biosynthesis|up regulation of acetylcholine biosynthetic process|up regulation of acetylcholine synthesis|positive regulation of acetylcholine biosynthesis|upregulation of acetylcholine biosynthesis|up-regulation of acetylcholine synthesis|up-regulation of acetylcholine formation|activation of acetylcholine formation|activation of acetylcholine anabolism|upregulation of acetylcholine anabolism|upregulation of acetylcholine biosynthetic process|up-regulation of acetylcholine biosynthesis|up regulation of acetylcholine formation|up regulation of acetylcholine anabolism|activation of acetylcholine synthesis|upregulation of acetylcholine formation|activation of acetylcholine biosynthesis							bc	2017-02-08T13:08:48Z					biological_process											owl:Class	
GO:2000133	biolink:NamedThing	positive regulation of tyramine signaling pathway	Any process that activates or increases the frequency, rate or extent of tyramine signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of tyramine signalling pathway							mah	2010-09-29T09:32:03Z					biological_process											owl:Class	
GO:0061312	biolink:NamedThing	BMP signaling pathway involved in heart development	A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, which contributes to the progression of the heart over time.	tmpzr1t_l9r_go_relaxed.owl	BMP signalling pathway involved in heart development							dph	2010-09-23T11:02:14Z					biological_process											owl:Class	
GO:0120178	biolink:NamedThing	steroid hormone biosynthetic process	The chemical reactions and pathways resulting in the formation of any steroid hormone, naturally occurring substances secreted by specialized cells that affects the metabolism or behavior of other cells possessing functional receptors for the hormone.	tmpzr1t_l9r_go_relaxed.owl								krc	2019-05-20T22:34:00Z					biological_process											owl:Class	
GO:0062230	biolink:NamedThing	negative regulation of larval somatic muscle development	Any process that decreases the rate, frequency or extent of larval somatic muscle development.	tmpzr1t_l9r_go_relaxed.owl								dph	2020-03-16T13:46:48Z					biological_process											owl:Class	
GO:0016561	biolink:NamedThing	protein import into peroxisome matrix, translocation	The process in which proteins are moved across the peroxisomal membrane into the matrix. It is likely that the peroxisome targeting sequence receptor remains associated with cargo proteins during translocation.	tmpzr1t_l9r_go_relaxed.owl	protein translocation during peroxisome matrix protein import|protein transport into peroxisome matrix, translocation|protein translocation during protein transport into peroxisome matrix|peroxisome matrix protein import, translocation|peroxisome receptor translocation|protein translocation during protein import into peroxisome matrix													biological_process											owl:Class	
GO:0000936	biolink:NamedThing	primary cell septum	A cell septum that forms following nuclear division.	tmpzr1t_l9r_go_relaxed.owl	primary septum													cellular_component											owl:Class	
GO:0019207	biolink:NamedThing	kinase regulator activity	Modulates the activity of a kinase, an enzyme which catalyzes of the transfer of a phosphate group, usually from ATP, to a substrate molecule.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0070351	biolink:NamedThing	negative regulation of white fat cell proliferation	Any process that stops or decreases the rate or extent of white fat cell proliferation.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of white fat cell proliferation|negative regulation of white adipose cell proliferation|inhibition of white fat cell proliferation|downregulation of white fat cell proliferation|down regulation of white fat cell proliferation|negative regulation of white adipocyte proliferation													biological_process											owl:Class	
GO:0070345	biolink:NamedThing	negative regulation of fat cell proliferation	Any process that stops or decreases the rate or extent of fat cell proliferation.	tmpzr1t_l9r_go_relaxed.owl	down regulation of fat cell proliferation|inhibition of fat cell proliferation|down-regulation of fat cell proliferation|negative regulation of adipocyte proliferation|negative regulation of adipose cell proliferation|downregulation of fat cell proliferation													biological_process											owl:Class	
GO:0032996	biolink:NamedThing	Bcl3-Bcl10 complex	A protein complex containing Bcl3 and Bcl10, which forms when Akt1 is activated by TNF-alpha to phosphorylate Bcl10; the Bcl3-Bcl10 complex is translocated to the nucleus.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0009506	biolink:NamedThing	plasmodesma	A fine cytoplasmic channel, found in all higher plants, that connects the cytoplasm of one cell to that of an adjacent cell.	tmpzr1t_l9r_go_relaxed.owl	plasmodesmata				Wikipedia:Plasmodesma									cellular_component											owl:Class	
GO:0070860	biolink:NamedThing	RNA polymerase I core factor complex	A RNA polymerase I-specific transcription factor complex that is required for the transcription of rDNA by RNA polymerase I. In yeast the complex consists of Rrn6p, Rrn7p, and Rrn11p.	tmpzr1t_l9r_go_relaxed.owl						Note that, although this complex can be considered analogous to the mammalian transcription factor SL complex, the core factor complex does not include TBP, whereas SL1 does.		mah	2009-08-14T05:00:44Z					cellular_component											owl:Class	
GO:1902232	biolink:NamedThing	regulation of positive thymic T cell selection	Any process that modulates the frequency, rate or extent of positive thymic T cell selection.	tmpzr1t_l9r_go_relaxed.owl	regulation of positive thymic T-cell selection|regulation of positive thymic T-lymphocyte selection|regulation of positive thymic T lymphocyte selection							lb	2013-06-14T11:19:09Z					biological_process											owl:Class	
GO:2000240	biolink:NamedThing	positive regulation of tRNA export from nucleus	Any process that activates or increases the frequency, rate or extent of tRNA export from nucleus.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of tRNA export from cell nucleus|positive regulation of tRNA export out of nucleus|positive regulation of tRNA transport from nucleus to cytoplasm|positive regulation of tRNA-nucleus export							mah	2010-11-10T12:39:38Z					biological_process											owl:Class	
GO:0033784	biolink:NamedThing	senecionine N-oxygenase activity	Catalysis of the reaction: H(+) + NADPH + O(2) + senecionine = H(2)O + NADP(+) + senecionine N-oxide.	tmpzr1t_l9r_go_relaxed.owl	SNO|senecionine,NADPH:oxygen oxidoreductase (N-oxide-forming) activity|senecionine monooxygenase (N-oxide-forming) activity				KEGG_REACTION:R07373|MetaCyc:1.14.13.101-RXN|EC:1.14.13.101|RHEA:11420									molecular_function											owl:Class	
GO:0043712	biolink:NamedThing	2-hydroxyisocaproate CoA-transferase activity	Catalysis of the reaction: (R)-2-hydroxyisocaproate + isocaproyl-CoA = (R)-2-hydroxyisocaproyl-CoA + isocaproate.	tmpzr1t_l9r_go_relaxed.owl	(R)-2-hydroxyisocaproate CoA transferase activity|(R)-2-hydroxyisocaproate CoA-transferase activity													molecular_function											owl:Class	
GO:0019592	biolink:NamedThing	mannitol catabolic process	The chemical reactions and pathways resulting in the breakdown of mannitol, the alditol derived from D-mannose by reduction of the aldehyde group.	tmpzr1t_l9r_go_relaxed.owl	mannitol degradation|mannitol breakdown|mannitol catabolism				MetaCyc:MANNIDEG-PWY|MetaCyc:PWY-3861									biological_process											owl:Class	
GO:0019594	biolink:NamedThing	mannitol metabolic process	The chemical reactions and pathways involving mannitol, the alditol derived from D-mannose by reduction of the aldehyde group.	tmpzr1t_l9r_go_relaxed.owl	mannitol metabolism													biological_process											owl:Class	
GO:0046427	biolink:NamedThing	positive regulation of receptor signaling pathway via JAK-STAT	Any process that activates or increases the frequency, rate or extent of the JAK-STAT signaling pathway activity.	tmpzr1t_l9r_go_relaxed.owl	up regulation of JAK-STAT cascade|positive regulation of STAT protein import into nucleus|positive regulation of STAT protein nuclear translocation|activation of JAK-STAT cascade|upregulation of JAK-STAT cascade|stimulation of JAK-STAT cascade|up-regulation of JAK-STAT cascade											GO:2000366		biological_process											owl:Class	
GO:0046425	biolink:NamedThing	regulation of receptor signaling pathway via JAK-STAT	Any process that modulates the frequency, rate or extent of receptor signaling via JAK-STAT.	tmpzr1t_l9r_go_relaxed.owl	STAT protein import into nucleus|regulation of STAT protein nuclear translocation|regulation of STAT protein import into nucleus	https://github.com/geneontology/go-ontology/issues/13686										GO:2000364|GO:0007262		biological_process											owl:Class	
GO:0043452	biolink:NamedThing	cellular alkyne metabolic process	The chemical reactions and pathways involving an alkyne, any acyclic branched or unbranched hydrocarbon (compound composed only of carbon and hydrogen) having a carbon-carbon triple bond and the general formula CnH2n-2, as carried out by individual cells.	tmpzr1t_l9r_go_relaxed.owl	alkyne metabolism													biological_process											owl:Class	
GO:0090095	biolink:NamedThing	regulation of metanephric cap mesenchymal cell proliferation	Any process that modulates the frequency, rate, or extent of metanephric cap mesenchymal cell proliferation. Metanephric cap mesenchymal cell proliferation is the multiplication or reproduction of metanephric cap mesenchymal cells, resulting in the expansion of the cell population. A metanephric cap mesenchymal cell is a mesenchymal cell that has condensed with other mesenchymal cells surrounding the ureteric bud tip.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-11-13T10:40:32Z					biological_process											owl:Class	
GO:1901722	biolink:NamedThing	regulation of cell proliferation involved in kidney development	Any process that modulates the frequency, rate or extent of cell proliferation involved in kidney development.	tmpzr1t_l9r_go_relaxed.owl								krc	2012-12-27T19:30:31Z					biological_process											owl:Class	
GO:0006868	biolink:NamedThing	glutamine transport	The directed movement of glutamine, 2-amino-4-carbamoylbutanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	L-glutamine transport											GO:0015815		biological_process											owl:Class	
GO:0032536	biolink:NamedThing	regulation of cell projection size	A process that modulates the size of a cell projection.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0015417	biolink:NamedThing	ABC-type polyamine transporter activity	Catalysis of the reaction: ATP + H2O + polyamine(out) = ADP + phosphate + polyamine(in).	tmpzr1t_l9r_go_relaxed.owl	polyamine porter activity|polyamine-transporting ATPase activity|polyamine-importing ATPase activity|ATP-dependent polyamine transmembrane transporter activity|ATPase-coupled polyamine transmembrane transporter activity|spermidine porter activity|polyamine ABC transporter|spermidine-importing ATPase activity|ATPase-coupled spermidine transmembrane transporter activity				MetaCyc:ABC-24-RXN|RHEA:29999|MetaCyc:3.6.3.31-RXN|EC:7.6.2.11							GO:0015595		molecular_function											owl:Class	
GO:0042400	biolink:NamedThing	ectoine catabolic process	The chemical reactions and pathways resulting in the breakdown of ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidinecarboxylic acid), a tetrahydropyrimidine commonly synthesized by halophilic bacteria.	tmpzr1t_l9r_go_relaxed.owl	ectoine breakdown|ectoine catabolism|ectoine degradation													biological_process											owl:Class	
GO:0097710	biolink:NamedThing	viral terminase, small subunit	The part of the viral terminase complex that acts as a phage DNA-recognition component and regulates the activity of the large subunit. The small subunit usually assembles as a heterooligomer with the large subunit.	tmpzr1t_l9r_go_relaxed.owl	virus terminase, small subunit					This term should only be used when the small subunit consists of more than one polypeptide.		pr	2016-06-07T12:45:00Z					cellular_component											owl:Class	
GO:0031299	biolink:NamedThing	taurine-pyruvate aminotransferase activity	Catalysis of the reaction: pyruvate + taurine = L-alanine + sulfoacetaldehyde.	tmpzr1t_l9r_go_relaxed.owl	taurine:pyruvate aminotransferase activity|Tpa				KEGG_REACTION:R05652|EC:2.6.1.77|MetaCyc:TAURINE-AMINOTRANSFERASE-RXN|RHEA:10420									molecular_function											owl:Class	
GO:0000965	biolink:NamedThing	mitochondrial RNA 3'-end processing	Any process involved in forming the mature 3' end of an RNA molecule transcribed from a mitochondrial genome; occurs in the mitochondrion.	tmpzr1t_l9r_go_relaxed.owl	mitochondrial RNA 3' end processing													biological_process											owl:Class	
GO:0035269	biolink:NamedThing	protein O-linked mannosylation	The transfer of mannose from dolichyl activated mannose to the hydroxyl group of a seryl or threonyl residue of a protein acceptor molecule, to form an O-linked protein-sugar linkage.	tmpzr1t_l9r_go_relaxed.owl	protein amino acid O-linked mannosylation													biological_process											owl:Class	
GO:0033872	biolink:NamedThing	[heparan sulfate]-glucosamine 3-sulfotransferase 3 activity	Catalysis of the reaction: 3'-phosphoadenylyl sulfate + [heparan sulfate]-glucosamine = adenosine 3',5'-bisphosphate + [heparan sulfate]-glucosamine 3-sulfate.	tmpzr1t_l9r_go_relaxed.owl	glucosaminyl 3-O-sulfotransferase 3a, 3b activity|isoform/isozyme 3a and 3b (3-OST-3A, 3-OST-3B, HS3ST3A, HS3ST3B)|heparin-glucosamine 3-sulfotransferase 3 activity|3'-phosphoadenylyl-sulfate:[heparan sulfate]-glucosamine 3-sulfotransferase activity|glucosaminyl 3-O-sulfotransferase 3 activity|heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3A activity|heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3 activity|3-OST-3				MetaCyc:2.8.2.30-RXN|EC:2.8.2.30									molecular_function											owl:Class	
GO:0034483	biolink:NamedThing	heparan sulfate sulfotransferase activity	Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + heparan sulfate = adenosine 3',5'-bisphosphate + sulfated heparan sulfate.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0046110	biolink:NamedThing	xanthine metabolic process	The chemical reactions and pathways involving xanthine, 2,6-dihydroxypurine, a purine formed in the metabolic breakdown of guanine but not present in nucleic acids.	tmpzr1t_l9r_go_relaxed.owl	xanthine metabolism													biological_process											owl:Class	
GO:0060833	biolink:NamedThing	Wnt signaling pathway involved in animal/vegetal axis specification	The series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of the target cell contributing to the specification of the animal/vegetal axis of an oocyte.	tmpzr1t_l9r_go_relaxed.owl	Wnt receptor signalling pathway involved in animal/vegetal axis specification|Wnt- activated signaling pathway involved in animal/vegetal axis specification|Wnt receptor signaling pathway involved in animal/vegetal axis specification							dph	2009-08-11T03:20:39Z					biological_process											owl:Class	
GO:0070409	biolink:NamedThing	carbamoyl phosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of carbamoyl phosphate, an intermediate in the urea cycle and other nitrogen compound metabolic pathways.	tmpzr1t_l9r_go_relaxed.owl	carbamoyl phosphate anabolism|carbamyl phosphate biosynthetic process|carbamoyl phosphate formation|carbamoyl phosphate biosynthesis|carbamoyl phosphate synthesis													biological_process											owl:Class	
GO:0097508	biolink:NamedThing	xanthine DNA N-glycosylase activity	DNA N-glycosylase activity acting on deaminated guanine (xanthine).	tmpzr1t_l9r_go_relaxed.owl	xanthine-DNA glycosylase activity							pr	2013-09-26T16:03:10Z					molecular_function											owl:Class	
GO:0097506	biolink:NamedThing	deaminated base DNA N-glycosylase activity	DNA N-glycosylase activity acting on deaminated bases.	tmpzr1t_l9r_go_relaxed.owl	DNA glycosylase activity acting on deaminated bases|deaminated base DNA glycosylase activity							pr	2013-09-26T16:00:40Z					molecular_function											owl:Class	
GO:1903618	biolink:NamedThing	regulation of transdifferentiation	Any process that modulates the frequency, rate or extent of transdifferentiation.	tmpzr1t_l9r_go_relaxed.owl								jl	2014-11-19T11:24:57Z					biological_process											owl:Class	
GO:0110013	biolink:NamedThing	positive regulation of aggregation involved in sorocarp development	Any process that increases the frequency, rate or extent of aggregation involved in sorocarp development. Aggregation involved in sorocarp development is the process whose specific outcome is the progression of the aggregate over time, from its formation to the point when a slug is formed. Aggregate development begins in response to starvation and continues by the chemoattractant-mediated movement of cells toward each other. The aggregate is a multicellular structure that gives rise to the slug.	tmpzr1t_l9r_go_relaxed.owl								kmv	2017-05-10T12:52:46Z					biological_process											owl:Class	
GO:0001811	biolink:NamedThing	negative regulation of type I hypersensitivity	Any process that stops, prevents, or reduces the rate of type I hypersensitivity, a type of inflammatory response.	tmpzr1t_l9r_go_relaxed.owl	inhibition of type I hypersensitivity|downregulation of type I hypersensitivity|down regulation of type I hypersensitivity|down-regulation of type I hypersensitivity													biological_process											owl:Class	
GO:0003953	biolink:NamedThing	NAD+ nucleosidase activity	Catalysis of the reaction: NAD+ + H2O = nicotinamide + ADP-ribose.	tmpzr1t_l9r_go_relaxed.owl	NAD nucleosidase activity				RHEA:16301|Reactome:R-HSA-8938076|Reactome:R-HSA-8870346									molecular_function											owl:Class	
GO:0016922	biolink:NamedThing	nuclear receptor binding	Binding to a nuclear receptor protein. Nuclear receptor proteins are DNA-binding transcription factors which are regulated by binding to a ligand.	tmpzr1t_l9r_go_relaxed.owl	ligand-dependent nuclear receptor interactor activity|nuclear hormone receptor binding|steroid hormone receptor binding|ligand-dependent nuclear receptor binding											GO:0035258|GO:0035257		molecular_function											owl:Class	
GO:0061629	biolink:NamedThing	RNA polymerase II-specific DNA-binding transcription factor binding	Binding to a sequence-specific DNA binding RNA polymerase II transcription factor, any of the factors that interact selectively and non-covalently with a specific DNA sequence in order to modulate transcription.	tmpzr1t_l9r_go_relaxed.owl	RNA polymerase II transcription factor binding|RNA polymerase II sequence-specific DNA-binding transcription factor binding|RNA polymerase II repressing transcription factor binding|RNA polymerase II sequence-specific DNA binding transcription factor binding|RNA polymerase II activating transcription factor binding	https://github.com/geneontology/go-ontology/issues/19354						dph	2014-05-15T09:12:24Z			GO:0001103|GO:0001102|GO:0001085		molecular_function											owl:Class	
GO:0014053	biolink:NamedThing	negative regulation of gamma-aminobutyric acid secretion	Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of gamma-aminobutyric acid.	tmpzr1t_l9r_go_relaxed.owl	down regulation of gamma-aminobutyric acid secretion|downregulation of gamma-aminobutyric acid secretion|down-regulation of gamma-aminobutyric acid secretion|inhibition of gamma-aminobutyric acid secretion|negative regulation of GABA secretion													biological_process											owl:Class	
GO:0034239	biolink:NamedThing	regulation of macrophage fusion	Any process that modulates the frequency, rate or extent of macrophage fusion.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1900925	biolink:NamedThing	positive regulation of glycine import across plasma membrane	Any process that activates or increases the frequency, rate or extent of glycine import.	tmpzr1t_l9r_go_relaxed.owl	up regulation of glycine import|upregulation of glycine import|up-regulation of glycine import|activation of glycine import|positive regulation of glycine import							al	2012-06-13T07:40:40Z					biological_process											owl:Class	
GO:0051957	biolink:NamedThing	positive regulation of amino acid transport	Any process that activates, maintains or increases the frequency, rate or extent of the directed movement of amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of amino acid transmembrane transport|up regulation of amino acid transport|stimulation of amino acid transport|activation of amino acid transport|up-regulation of amino acid transport|upregulation of amino acid transport													biological_process											owl:Class	
GO:0070234	biolink:NamedThing	positive regulation of T cell apoptotic process	Any process that activates or increases the frequency, rate or extent of T cell death by apoptotic process.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of T cell apoptosis|positive regulation of T-lymphocyte apoptosis|upregulation of T cell apoptosis|positive regulation of T lymphocyte apoptosis|positive regulation of programmed cell death of T cells by apoptosis|up-regulation of T cell apoptosis|positive regulation of T-cell apoptosis|stimulation of T cell apoptosis|up regulation of T cell apoptosis|activation of T cell apoptosis													biological_process											owl:Class	
GO:0051900	biolink:NamedThing	regulation of mitochondrial depolarization	Any process that modulates the frequency, rate or extent of the change in the membrane potential of the mitochondria from negative to positive.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0090337	biolink:NamedThing	regulation of formin-nucleated actin cable assembly	Any process that modulates the rate, frequency, or extent of formin-nucleated actin cable assembly. Formin-nucleated actin cable assembly is the aggregation, arrangement and bonding together of a set of components to form a formin-nucleated actin cable. A formin-nucleated actin cable is an actin filament bundle that consists of short filaments organized into bundles of uniform polarity, and is nucleated by formins.	tmpzr1t_l9r_go_relaxed.owl								tb	2010-06-01T03:26:31Z					biological_process											owl:Class	
GO:0070866	biolink:NamedThing	sterol-dependent protein binding	Binding to a protein or protein complex in the presence of sterols.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-08-19T01:43:35Z					molecular_function											owl:Class	
GO:0002631	biolink:NamedThing	regulation of granuloma formation	Any process that modulates the frequency, rate, or extent of granuloma formation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1901598	biolink:NamedThing	(-)-pinoresinol metabolic process	The chemical reactions and pathways involving (-)-pinoresinol.	tmpzr1t_l9r_go_relaxed.owl	(-)-pinoresinol metabolism							tb	2012-11-08T01:15:57Z					biological_process											owl:Class	
GO:0032032	biolink:NamedThing	myosin I tail binding	Binding to the tail region of a myosin I heavy chain.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0032029	biolink:NamedThing	myosin tail binding	Binding to the tail region of a myosin heavy chain.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0030172	biolink:NamedThing	troponin C binding	Binding to troponin C, the calcium-binding subunit of the troponin complex.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0006325	biolink:NamedThing	chromatin organization	Any process that results in the specification, formation or maintenance of the physical structure of eukaryotic chromatin.	tmpzr1t_l9r_go_relaxed.owl	chromatin modification|chromatin organisation|establishment or maintenance of chromatin architecture											GO:0016568		biological_process											owl:Class	
GO:0035997	biolink:NamedThing	rhabdomere microvillus membrane	The portion of the plasma membrane surrounding a microvillus of a rhabdomere.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-09-01T02:24:20Z					cellular_component											owl:Class	
GO:0031528	biolink:NamedThing	microvillus membrane	The portion of the plasma membrane surrounding a microvillus.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0035485	biolink:NamedThing	adenine/guanine mispair binding	Binding to a double-stranded DNA region containing an A/G mispair.	tmpzr1t_l9r_go_relaxed.owl	guanine-adenine mispair binding|G/A mispair binding|A/G mispair binding							bf	2010-04-23T10:55:43Z					molecular_function											owl:Class	
GO:1905463	biolink:NamedThing	negative regulation of DNA duplex unwinding	Any process that stops, prevents or reduces the frequency, rate or extent of DNA duplex unwinding.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of DNA unwinding|down-regulation of DNA unwinding|down regulation of duplex DNA melting|downregulation of DNA unwinding|inhibition of duplex DNA melting|downregulation of duplex DNA melting|down-regulation of duplex DNA melting|inhibition of DNA duplex unwinding|down regulation of DNA unwinding|down-regulation of DNA duplex unwinding|negative regulation of duplex DNA melting|down regulation of DNA duplex unwinding|downregulation of DNA duplex unwinding|inhibition of DNA unwinding							ans	2016-09-19T11:58:48Z					biological_process											owl:Class	
GO:2001251	biolink:NamedThing	negative regulation of chromosome organization	Any process that stops, prevents or reduces the frequency, rate or extent of chromosome organization.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of chromosome organisation|negative regulation of maintenance of genome integrity|negative regulation of chromosome organization and biogenesis|negative regulation of nuclear genome maintenance							yaf	2011-12-02T02:01:20Z					biological_process											owl:Class	
GO:0006570	biolink:NamedThing	tyrosine metabolic process	The chemical reactions and pathways involving tyrosine, an aromatic amino acid, 2-amino-3-(4-hydroxyphenyl)propanoic acid.	tmpzr1t_l9r_go_relaxed.owl	tyrosine metabolism				Wikipedia:Tyrosine|UM-BBD_pathwayID:tyr									biological_process											owl:Class	
GO:1990274	biolink:NamedThing	mitotic actomyosin contractile ring disassembly	Any disaggregation of an actomyosin contractile ring into its constituent components that is involved in a mitotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl	mitotic CAR disassembly|mitotic actomyosin ring disassembly|mitotic contractile actomyosin ring disassembly|mitotic constriction ring disassembly|mitotic cytokinetic ring disassembly							mah	2014-01-16T10:25:42Z					biological_process											owl:Class	
GO:1903507	biolink:NamedThing	negative regulation of nucleic acid-templated transcription	Any process that stops, prevents or reduces the frequency, rate or extent of nucleic acid-templated transcription.	tmpzr1t_l9r_go_relaxed.owl	downregulation of nucleic acid-templated transcription|down regulation of nucleic acid-templated transcription|inhibition of nucleic acid-templated transcription|down-regulation of nucleic acid-templated transcription							pr	2014-10-01T14:44:56Z					biological_process											owl:Class	
GO:1902679	biolink:NamedThing	negative regulation of RNA biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of RNA biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	downregulation of RNA biosynthesis|down regulation of RNA biosynthetic process|down-regulation of RNA anabolism|downregulation of RNA biosynthetic process|down-regulation of RNA biosynthetic process|down regulation of RNA formation|inhibition of RNA biosynthesis|downregulation of RNA formation|down-regulation of RNA synthesis|negative regulation of RNA formation|negative regulation of RNA synthesis|inhibition of RNA biosynthetic process|down regulation of RNA biosynthesis|negative regulation of RNA biosynthesis|downregulation of RNA synthesis|inhibition of RNA synthesis|down regulation of RNA anabolism|negative regulation of RNA anabolism|down-regulation of RNA formation|inhibition of RNA anabolism|downregulation of RNA anabolism|down regulation of RNA synthesis|inhibition of RNA formation|down-regulation of RNA biosynthesis							jl	2014-02-05T16:32:01Z					biological_process											owl:Class	
GO:0086070	biolink:NamedThing	SA node cell to atrial cardiac muscle cell communication	The process that mediates interactions between an SA node cardiomyocyte and its surroundings that contributes to the process of the SA node cardiomyocyte communicating with an atrial cardiomyocyte in cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.	tmpzr1t_l9r_go_relaxed.owl	sinus node cardiomyocyte to atrial cardiomyocyte communication|SA node cardiomyocyte to atrial cardiomyocyte communication|SAN cardiomyocyte to atrial cardiomyocyte communication|sinoatrial node cardiomyocyte to atrial cardiomyocyte communication|SA node cardiac muscle cell to atrial cardiac muscle cell communication							dph	2011-11-22T09:32:45Z					biological_process											owl:Class	
GO:1990169	biolink:NamedThing	stress response to copper ion	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis caused by a copper ion stimulus.	tmpzr1t_l9r_go_relaxed.owl	stress response to copper|response to copper toxicity|response to copper ion stress							pr	2013-08-14T12:52:05Z					biological_process											owl:Class	
GO:0030788	biolink:NamedThing	precorrin-2 C20-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + precorrin-2 = S-adenosyl-L-homocysteine + H(+) + precorrin-3A.	tmpzr1t_l9r_go_relaxed.owl	S-adenosyl-L-methionine--precorrin-2 methyltransferase activity|S-adenosyl-L-methionine:precorrin-4 C20-methyltransferase activity				KEGG_REACTION:R03948|EC:2.1.1.130|MetaCyc:2.1.1.130-RXN|RHEA:16841									molecular_function											owl:Class	
GO:0019972	biolink:NamedThing	interleukin-12 binding	Binding to interleukin-12.	tmpzr1t_l9r_go_relaxed.owl	IL-12 binding													molecular_function											owl:Class	
GO:1904581	biolink:NamedThing	negative regulation of intracellular mRNA localization	Any process that stops, prevents or reduces the frequency, rate or extent of intracellular mRNA localization.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of establishment and maintenance of intracellular RNA localization|inhibition of intracellular mRNA localization|negative regulation of intracellular mRNA localisation|negative regulation of establishment and maintenance of intracellular RNA localization|down-regulation of intracellular mRNA localisation|inhibition of establishment and maintenance of intracellular RNA localization|down-regulation of mRNA positioning, intracellular|negative regulation of intracellular mRNA positioning|inhibition of mRNA localization, intracellular|down regulation of establishment and maintenance of intracellular RNA localization|inhibition of mRNA positioning, intracellular|negative regulation of mRNA localization, intracellular|downregulation of intracellular mRNA localisation|down-regulation of intracellular mRNA positioning|downregulation of intracellular mRNA positioning|down regulation of mRNA positioning, intracellular|down regulation of intracellular mRNA localisation|negative regulation of mRNA positioning, intracellular|downregulation of intracellular mRNA localization|down-regulation of intracellular mRNA localization|down-regulation of mRNA localization, intracellular|downregulation of mRNA localization, intracellular|down regulation of mRNA localization, intracellular|downregulation of establishment and maintenance of intracellular RNA localization|downregulation of mRNA positioning, intracellular|down regulation of intracellular mRNA positioning|inhibition of intracellular mRNA positioning|down regulation of intracellular mRNA localization|inhibition of intracellular mRNA localisation							sl	2015-08-19T23:40:32Z					biological_process											owl:Class	
GO:1904580	biolink:NamedThing	regulation of intracellular mRNA localization	Any process that modulates the frequency, rate or extent of intracellular mRNA localization.	tmpzr1t_l9r_go_relaxed.owl	regulation of intracellular mRNA positioning|regulation of mRNA positioning, intracellular|regulation of intracellular mRNA localisation|regulation of mRNA localization, intracellular|regulation of establishment and maintenance of intracellular RNA localization							sl	2015-08-19T23:40:25Z					biological_process											owl:Class	
GO:0046152	biolink:NamedThing	ommochrome metabolic process	The chemical reactions and pathways involving ommochromes, any of a large group of natural polycyclic pigments commonly found in the Arthropoda, particularly in the ommatidia of the compound eye.	tmpzr1t_l9r_go_relaxed.owl	ommochrome metabolism													biological_process											owl:Class	
GO:0071469	biolink:NamedThing	cellular response to alkaline pH	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus with pH > 7. pH is a measure of the acidity or basicity of an aqueous solution.	tmpzr1t_l9r_go_relaxed.owl	cellular response to basic pH|cellular response to alkalinity							mah	2009-12-18T11:42:47Z					biological_process											owl:Class	
GO:0010446	biolink:NamedThing	response to alkaline pH	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus with pH > 7. pH is a measure of the acidity or basicity of an aqueous solution.	tmpzr1t_l9r_go_relaxed.owl	response to basic pH|response to alkalinity													biological_process											owl:Class	
GO:1904495	biolink:NamedThing	negative regulation of substance P secretion, neurotransmission	Any process that stops, prevents or reduces the frequency, rate or extent of substance P secretion, neurotransmission.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of substance P secretion, neurotransmission|inhibition of substance P secretion, neurotransmission|down regulation of substance P secretion, neurotransmission|downregulation of substance P secretion, neurotransmission							sl	2015-07-21T19:09:10Z					biological_process											owl:Class	
GO:0021632	biolink:NamedThing	optic nerve maturation	A developmental process, independent of morphogenetic (shape) change, that is required for the optic nerve to attain its fully functional state. The sensory optic nerve originates from the bipolar cells of the retina and conducts visual information to the brainstem. The optic nerve exits the back of the eye in the orbit, enters the optic canal, and enters the central nervous system at the optic chiasm (crossing) where the nerve fibers become the optic tract just prior to entering the hindbrain.	tmpzr1t_l9r_go_relaxed.owl	CN II maturation													biological_process											owl:Class	
GO:1900848	biolink:NamedThing	positive regulation of naphtho-gamma-pyrone biosynthetic process	Any process that activates or increases the frequency, rate or extent of naphtho-gamma-pyrone biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	upregulation of naphtho-gamma-pyrone biosynthetic process|up regulation of naphtho-gamma-pyrone biosynthetic process|activation of naphtho-gamma-pyrone biosynthetic process|up-regulation of naphtho-gamma-pyrone biosynthetic process							di	2012-06-07T09:43:11Z					biological_process											owl:Class	
GO:1900846	biolink:NamedThing	regulation of naphtho-gamma-pyrone biosynthetic process	Any process that modulates the frequency, rate or extent of naphtho-gamma-pyrone biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of naphtho-gamma-pyrones synthesis|regulation of naphtho-gamma-pyrone biosynthesis|regulation of naphtho-gamma-pyrone formation|regulation of naphtho-gamma-pyrone anabolism|regulation of naphtho-gamma-pyrones formation|regulation of naphtho-gamma-pyrones biosynthesis|regulation of naphtho-gamma-pyrones anabolism|regulation of naphtho-gamma-pyrones biosynthetic process|regulation of naphtho-gamma-pyrone synthesis							di	2012-06-07T09:42:41Z					biological_process											owl:Class	
GO:0044785	biolink:NamedThing	metaphase/anaphase transition of meiotic cell cycle	The cell cycle process in which a cell progresses from metaphase to anaphase as part of meiosis.	tmpzr1t_l9r_go_relaxed.owl	meiotic metaphase/anaphase transition							jl	2013-05-02T13:11:28Z					biological_process											owl:Class	
GO:0044771	biolink:NamedThing	meiotic cell cycle phase transition	The cell cycle process by which a cell commits to entering the next meiotic cell cycle phase.	tmpzr1t_l9r_go_relaxed.owl	cell cycle transition							jl	2013-02-28T13:08:17Z					biological_process											owl:Class	
GO:1901092	biolink:NamedThing	positive regulation of protein tetramerization	Any process that activates or increases the frequency, rate or extent of protein tetramerization.	tmpzr1t_l9r_go_relaxed.owl	up regulation of protein tetramer assembly|positive regulation of protein tetramer assembly|up-regulation of protein tetramer biosynthetic process|positive regulation of protein tetramer biosynthetic process|upregulation of protein tetramer biosynthetic process|up regulation of protein tetramerization|positive regulation of protein tetramer formation|activation of protein tetramer biosynthetic process|upregulation of protein tetramer assembly|up regulation of protein tetramer formation|upregulation of protein tetramerization|up-regulation of protein tetramer biosynthesis|up-regulation of protein tetramerization|activation of protein tetramer formation|up regulation of protein tetramer biosynthesis|up-regulation of protein tetramer formation|up regulation of protein tetramer biosynthetic process|activation of protein tetramer biosynthesis|up-regulation of protein tetramer assembly|upregulation of protein tetramer formation|activation of protein tetramer assembly|upregulation of protein tetramer biosynthesis|activation of protein tetramerization|positive regulation of protein tetramer biosynthesis							pm	2012-07-06T12:51:32Z					biological_process											owl:Class	
GO:0002734	biolink:NamedThing	negative regulation of myeloid dendritic cell cytokine production	Any process that stops, prevents, or reduces the frequency, rate, or extent of myeloid dendritic cell cytokine production.	tmpzr1t_l9r_go_relaxed.owl	downregulation of myeloid dendritic cell cytokine production|down-regulation of myeloid dendritic cell cytokine production|inhibition of myeloid dendritic cell cytokine production|down regulation of myeloid dendritic cell cytokine production													biological_process											owl:Class	
GO:0090127	biolink:NamedThing	positive regulation of synapse maturation by synaptic transmission	Any process that increases the extent of synaptic maturation as a result of the communication from a pre-synaptic cell to a post-synaptic cell across a synapse.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-12-07T02:57:21Z					biological_process											owl:Class	
GO:0034215	biolink:NamedThing	thiamine:proton symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: thiamine(out) + H+(out) = thiamine(in) + H+(in).	tmpzr1t_l9r_go_relaxed.owl	thiamin:proton symporter activity|thiamin:hydrogen symporter activity|thiamine:hydrogen symporter activity													molecular_function											owl:Class	
GO:0050758	biolink:NamedThing	regulation of thymidylate synthase biosynthetic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of the enzyme thymidylate synthase.	tmpzr1t_l9r_go_relaxed.owl	regulation of thymidylate synthase biosynthesis|regulation of thymidylate synthase synthesis|regulation of thymidylate synthase formation|regulation of thymidylate synthase anabolism													biological_process											owl:Class	
GO:0018352	biolink:NamedThing	protein-pyridoxal-5-phosphate linkage	The formation of a linkage between a protein amino acid and pyridoxal-5-phosphate.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1901041	biolink:NamedThing	positive regulation of peptide antigen transport	Any process that activates or increases the frequency, rate or extent of peptide antigen transport.	tmpzr1t_l9r_go_relaxed.owl	up regulation of peptide antigen transport|upregulation of peptide antigen transport|up-regulation of peptide antigen transport|activation of peptide antigen transport							bf	2012-06-22T04:08:26Z					biological_process											owl:Class	
GO:0021766	biolink:NamedThing	hippocampus development	The progression of the hippocampus over time from its initial formation until its mature state.	tmpzr1t_l9r_go_relaxed.owl	hippocampal formation development													biological_process											owl:Class	
GO:0047198	biolink:NamedThing	cysteine-S-conjugate N-acetyltransferase activity	Catalysis of the reaction: S-substituted L-cysteine + acetyl-CoA = S-substituted N-acetyl-L-cysteine + CoA + H(+).	tmpzr1t_l9r_go_relaxed.owl	acetyl-CoA:S-substituted L-cysteine N-acetyltransferase activity				RHEA:19213|EC:2.3.1.80|MetaCyc:2.3.1.80-RXN|Reactome:R-HSA-5433066|KEGG_REACTION:R04950									molecular_function											owl:Class	
GO:0070184	biolink:NamedThing	mitochondrial tyrosyl-tRNA aminoacylation	The process of coupling tyrosine to tyrosyl-tRNA in a mitochondrion, catalyzed by tyrosyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0075526	biolink:NamedThing	cap snatching	A transcription initiation process during which a nucleotide sequence between 10 and 20 nucleotides in size is cleaved from the 5' end of host mRNAs by a viral RNA-dependent polymerase. The capped leader sequence obtained is subsequently used to prime transcription on the viral genome, which ultimately leads to the synthesis of capped, translatable viral mRNAs.	tmpzr1t_l9r_go_relaxed.owl	cap snatching involved in viral mRNA transcription				VZ:839			jl	2011-08-04T01:19:00Z					biological_process											owl:Class	
GO:0051029	biolink:NamedThing	rRNA transport	The directed movement of rRNA, ribosomal ribonucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0018015	biolink:NamedThing	N-terminal peptidyl-phenylalanine methylation	The methylation of the N-terminal phenylalanine of proteins to form the derivative N-methyl-L-phenylalanine.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0065									biological_process											owl:Class	
GO:0031319	biolink:NamedThing	detection of cAMP	The series of events in which a cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate) stimulus is received by a cell and converted into a molecular signal; cAMP is the nucleotide cyclic AMP.	tmpzr1t_l9r_go_relaxed.owl	cAMP detection|detection of 3',5' cAMP|cAMP sensing|detection of 3',5'-cAMP|cyclic AMP detection|detection of adenosine 3',5'-cyclophosphate|detection of cyclic AMP|3',5'-cAMP sensing|3',5'-cAMP detection													biological_process											owl:Class	
GO:1902909	biolink:NamedThing	negative regulation of melanosome transport	Any process that stops, prevents or reduces the frequency, rate or extent of melanosome transport.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of melanosome transport|downregulation of melanosome transport|inhibition of melanosome transport|down regulation of melanosome transport							als	2014-04-17T11:40:28Z					biological_process											owl:Class	
GO:1902908	biolink:NamedThing	regulation of melanosome transport	Any process that modulates the frequency, rate or extent of melanosome transport.	tmpzr1t_l9r_go_relaxed.owl								als	2014-04-17T11:40:16Z					biological_process											owl:Class	
GO:1901537	biolink:NamedThing	positive regulation of DNA demethylation	Any process that activates or increases the frequency, rate or extent of DNA demethylation.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of DNA demethylation|up regulation of DNA demethylation|upregulation of DNA demethylation|activation of DNA demethylation							jl	2012-10-24T13:52:59Z					biological_process											owl:Class	
GO:1904591	biolink:NamedThing	positive regulation of protein import	Any process that activates or increases the frequency, rate or extent of protein import.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of protein import|activation of protein import|up regulation of protein import|activation of protein uptake|upregulation of protein import|upregulation of protein uptake|up regulation of protein uptake|positive regulation of protein uptake|up-regulation of protein uptake							sl	2015-08-20T21:26:42Z					biological_process											owl:Class	
GO:1904589	biolink:NamedThing	regulation of protein import	Any process that modulates the frequency, rate or extent of protein import.	tmpzr1t_l9r_go_relaxed.owl	regulation of protein uptake							sl	2015-08-20T21:26:30Z					biological_process											owl:Class	
GO:0140682	biolink:NamedThing	histone H3-di/monomethyl-lysine-4 FAD-dependent demethylase activity	Catalysis of the removal of a methyl group from a di- or a monomethyl-lysine residue at position 4 of the histone H3 protein. This is a flavin adenine dinucleotide (FAD)-dependent amine oxidation reaction.	tmpzr1t_l9r_go_relaxed.owl	histone H3K4me demethylase activity|histone H3K4me2 demethylase activity	https://github.com/geneontology/go-ontology/issues/21089			EC:1.14.99.66|RHEA:60244			pg	2021-07-08T15:45:22Z					molecular_function											owl:Class	
GO:0072266	biolink:NamedThing	metanephric capsule formation	The developmental process pertaining to the initial formation of a metanephric capsule from unspecified parts. The metanephric capsule is the tough fibrous layer surrounding the metanephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-03-30T02:56:35Z					biological_process											owl:Class	
GO:0036316	biolink:NamedThing	SREBP-SCAP complex retention in endoplasmic reticulum	Any process in which the SREBP-SCAP complex is maintained in the endoplasmic reticulum and prevented from moving elsewhere. The SREBP-SCAP complex is formed by the association of sterol regulatory element binding protein (SREBP) and SREBP-cleavage-activating protein (SCAP). In the absence of sterols, the SREBP-SCAP complex is packaged into COPII vesicles and travels to the Golgi apparatus to be processed. In the presence of sterols, the complex binds ER-resident proteins such as INSIG, which retain the complex in the ER.	tmpzr1t_l9r_go_relaxed.owl						Consider also annotating to the cellular component term: SREBP-SCAP-Insig complex ; GO:0032937.		bf	2012-08-21T14:53:08Z					biological_process											owl:Class	
GO:0004337	biolink:NamedThing	geranyltranstransferase activity	Catalysis of the reaction: geranyl diphosphate + isopentenyl diphosphate = 2-trans,6-trans-farnesyl diphosphate + diphosphate.	tmpzr1t_l9r_go_relaxed.owl	geranyl transferase I|geranyl-diphosphate:isopentenyl-diphosphate geranyltranstransferase activity|farnesylpyrophosphate synthetase activity|farnesyl-diphosphate synthase activity|FPP synthetase activity|farnesyl diphosphate synthetase activity|geranyltransferase activity|farnesyl pyrophosphate synthetase activity				MetaCyc:FPPSYN-RXN|EC:2.5.1.10|Reactome:R-HSA-8870469|RHEA:19361|KEGG_REACTION:R02003|Reactome:R-HSA-191303	Note that this is the second step in the formation of farnesyl diphosphate. The first step is 'dimethylallyltransferase activity ; GO:0004161'. Consider also annotating to the biological process term 'farnesyl diphosphate biosynthetic process ; GO:0045337'.								molecular_function											owl:Class	
GO:1990781	biolink:NamedThing	response to immobilization stress combined with electrical stimulus	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electrical stimulus given while being held immobile.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-06-23T20:30:42Z					biological_process											owl:Class	
GO:0051602	biolink:NamedThing	response to electrical stimulus	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electrical stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to electricity													biological_process											owl:Class	
GO:1990012	biolink:NamedThing	complex laminated body	A cytoplasmic inclusion body found in some lateral geniculate neurons and composed of sheets of tubules (25 nm in diameter) separated by dense material (about 75 nm wide), which together with the tubules whorl give a structure resembling a fingerprint.	tmpzr1t_l9r_go_relaxed.owl	CLB				NIF_Subcellular:nlx_151681			pr	2012-12-12T14:18:15Z					cellular_component											owl:Class	
GO:1990011	biolink:NamedThing	laminated body	Inclusion body characterized by regularly spaced sheets of tubules arranged in a whorl pattern resembling a fingerprint. Laminated bodies have been observed in neurons of the lateral geniculate nucleus.	tmpzr1t_l9r_go_relaxed.owl	laminated inclusion body				NIF_Subcellular:sao506721981			pr	2012-12-12T14:12:21Z					cellular_component											owl:Class	
GO:0016580	biolink:NamedThing	Sin3 complex	A multiprotein complex that functions broadly in eukaryotic organisms as a transcriptional repressor of protein-coding genes, through the gene-specific deacetylation of histones. Amongst its subunits, the Sin3 complex contains Sin3-like proteins, and a number of core proteins that are shared with the NuRD complex (including histone deacetylases and histone binding proteins). The Sin3 complex does not directly bind DNA itself, but is targeted to specific genes through protein-protein interactions with DNA-binding proteins.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0070822	biolink:NamedThing	Sin3-type complex	Any of a number of evolutionarily conserved histone deacetylase complexes (HDACs) containing a core consisting of a paired amphipathic helix motif protein (e.g. Sin3p in S. cerevisiae, Pst1 in S. pombe or Sin3A in mammals) at least one class I histone deacetylase (e.g. Rpd3p in S. cerevisiae, Clr6 in S. pombe, or HDAC1 and HDAC2 in mammals), and at least one WD40 repeat protein (e.g. Ume1p in S. cerevisiae, Prw1 in S. pombe, or RbAp46 and RbAp48 in mammals). These complexes also contain a variable number of other proteins that direct histone binding, DNA binding, or add other functionality to the complex.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-07-20T04:32:33Z					cellular_component											owl:Class	
GO:0032467	biolink:NamedThing	positive regulation of cytokinesis	Any process that activates or increases the frequency, rate or extent of the division of the cytoplasm of a cell, and its separation into two daughter cells.	tmpzr1t_l9r_go_relaxed.owl	up regulation of cytokinesis|up-regulation of cytokinesis|positive regulation of cell cycle cytokinesis|activation of cytokinesis|upregulation of cytokinesis|stimulation of cytokinesis											GO:0071777		biological_process											owl:Class	
GO:0018562	biolink:NamedThing	3,4-dihydroxyfluorene 4,4-alpha-dioxygenase activity	Catalysis of the reaction: 3,4-dihydroxyfluorene + O2 = 2-hydroxy-4-(1-oxo-1,3-dihydro-2H-inden-2-ylidene) but-2-enoic acid.	tmpzr1t_l9r_go_relaxed.owl					EC:1.13.11.-|UM-BBD_reactionID:r0415									molecular_function											owl:Class	
GO:0019117	biolink:NamedThing	dihydroxyfluorene dioxygenase activity	Catalysis of the reaction: a dihydroxyfluorene + O2 = the corresponding 2-hydroxy-4-(oxo-1,3-dihydro-2H-inden-ylidene) but-2-enoic acid.	tmpzr1t_l9r_go_relaxed.owl					EC:1.13.11.-									molecular_function											owl:Class	
GO:0072340	biolink:NamedThing	cellular lactam catabolic process	The chemical reactions and pathways resulting in the breakdown of lactams, any cyclic amides of amino carboxylic acids, having a 1-azacycloalkan-2-one structure, or analogues having unsaturation or heteroatoms replacing one or more carbon atoms of the ring.	tmpzr1t_l9r_go_relaxed.owl	cellular lactam degradation|cellular lactam catabolism|cellular lactam breakdown							mah	2010-11-04T04:33:22Z					biological_process											owl:Class	
GO:0016041	biolink:NamedThing	glutamate synthase (ferredoxin) activity	Catalysis of the reaction: 2 L-glutamate + 2 oxidized ferredoxin = L-glutamine + 2-oxoglutarate + 2 reduced ferredoxin + 2 H+. This is a two-step reaction: (a) L-glutamate + NH3 = L-glutamine + H2O, (b) L-glutamate + 2 oxidized ferredoxin + H2O = NH3 + 2-oxoglutarate + 2 reduced ferredoxin + 2 H+.	tmpzr1t_l9r_go_relaxed.owl	L-glutamate:ferredoxin oxidoreductase (transaminating)|ferredoxin-dependent glutamate synthase activity|ferredoxin-glutamate synthase activity|glutamate synthase (ferredoxin-dependent)				MetaCyc:GLUTAMATE-SYNTHASE-FERREDOXIN-RXN|MetaCyc:PWY-4341|EC:1.4.7.1|RHEA:12128									molecular_function											owl:Class	
GO:0015930	biolink:NamedThing	glutamate synthase activity	Catalysis of the formation of L-glutamine and 2-oxoglutarate from L-glutamate, using NADH, NADPH or ferredoxin as hydrogen acceptors.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0004064	biolink:NamedThing	arylesterase activity	Catalysis of the reaction: a phenyl acetate + H2O = a phenol + acetate.	tmpzr1t_l9r_go_relaxed.owl	paraoxonase activity|aryl-ester hydrolase|A-esterase activity|aromatic esterase				UM-BBD_reactionID:r0757|MetaCyc:ARYLESTERASE-RXN|EC:3.1.1.2|RHEA:17309									molecular_function											owl:Class	
GO:0010246	biolink:NamedThing	rhamnogalacturonan I biosynthetic process	The chemical reactions and pathways resulting in the formation of rhamnogalacturonan I component of pectin, a rhamnose-rich pectic polysaccharide.	tmpzr1t_l9r_go_relaxed.owl	rhamnogalacturonan I anabolism|rhamnogalacturonan I biosynthesis|rhamnogalacturonan I formation|rhamnogalacturonan I synthesis													biological_process											owl:Class	
GO:0034494	biolink:NamedThing	microneme lumen	The volume enclosed by the microneme membrane.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0015822	biolink:NamedThing	ornithine transport	The directed movement of ornithine, 2,5-diaminopentanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	L-ornithine transport													biological_process											owl:Class	
GO:1901887	biolink:NamedThing	2-hydroxybenzoyl-CoA biosynthetic process	The chemical reactions and pathways resulting in the formation of 2-hydroxybenzoyl-CoA.	tmpzr1t_l9r_go_relaxed.owl	2-hydroxybenzoyl-CoA anabolism|2-hydroxybenzoyl-CoA biosynthesis|2-hydroxybenzoyl-CoA synthesis|2-hydroxybenzoyl-CoA formation							ms	2013-02-06T14:06:12Z					biological_process											owl:Class	
GO:1901885	biolink:NamedThing	2-hydroxybenzoyl-CoA metabolic process	The chemical reactions and pathways involving 2-hydroxybenzoyl-CoA.	tmpzr1t_l9r_go_relaxed.owl	2-hydroxybenzoyl-CoA metabolism							ms	2013-02-06T14:06:03Z					biological_process											owl:Class	
GO:0048462	biolink:NamedThing	carpel formation	The process that gives rise to the carpel. This process pertains to the initial formation of a structure from unspecified parts.	tmpzr1t_l9r_go_relaxed.owl												GO:0048431		biological_process											owl:Class	
GO:0008656	biolink:NamedThing	cysteine-type endopeptidase activator activity involved in apoptotic process	Binds to and increases the rate of proteolysis catalyzed by a cysteine-type endopeptidase involved in the apoptotic process.	tmpzr1t_l9r_go_relaxed.owl	caspase activator activity				Reactome:R-HSA-205117|Reactome:R-HSA-449073	Examples of this are 1) granzymes that may bind to initiator caspases and cleave them, and 2) already active caspases, e.g. caspase 9, that cleave effector caspases.								molecular_function											owl:Class	
GO:0016505	biolink:NamedThing	peptidase activator activity involved in apoptotic process	Binds to and increases the activity of a peptidase that is involved in the apoptotic process.	tmpzr1t_l9r_go_relaxed.owl	apoptotic protease activator activity													molecular_function											owl:Class	
GO:0140588	biolink:NamedThing	chromatin looping	A chromatin organization process that starts with the loading of an extrusion motor (by an SMC family complex) onto the chromatin, followed by chromatin extrusion that stops at loop anchoring sites on the chromosome.	tmpzr1t_l9r_go_relaxed.owl	chromatin folding|chromatin loop assembly|DNA looping|DNA loop extrusion	https://github.com/geneontology/go-ontology/issues/22109|https://github.com/geneontology/go-ontology/issues/20204				To describe the molecular function associated with chromatin looping, consider 'chromatin extrusion motor activity'; GO:0140584.		pg	2021-02-04T14:55:20Z					biological_process											owl:Class	
GO:0043409	biolink:NamedThing	negative regulation of MAPK cascade	Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the MAPKKK cascade.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of mitogen activated protein kinase kinase kinase cascade|down-regulation of MAPKKK cascade|negative regulation of MAP kinase cascade|down-regulation of MAPK cascade|negative regulation of mitogen-activated protein kinase cascade|negative regulation of MAPKKK cascade|inhibition of MAPK cascade|down regulation of MAPKKK cascade|downregulation of MAPK cascade|negative regulation of mitogen activated protein kinase cascade|downregulation of MAPKKK cascade|inhibition of MAPKKK cascade|down regulation of MAPK cascade|negative regulation of MAP kinase kinase kinase cascade|negative regulation of mitogen-activated protein kinase kinase kinase cascade													biological_process											owl:Class	
GO:0034370	biolink:NamedThing	triglyceride-rich lipoprotein particle remodeling	The acquisition, loss or modification of a protein or lipid within a triglyceride-rich lipoprotein particle, including the hydrolysis of triglyceride by lipoprotein lipase, with the subsequent loss of free fatty acid, and the transfer of cholesterol esters to a triglyceride-rich lipoprotein particle by cholesteryl ester transfer protein (CETP), with the simultaneous transfer of triglyceride from a triglyceride-rich lipoprotein particle.	tmpzr1t_l9r_go_relaxed.owl	triacylglycerol-rich lipoprotein particle remodeling													biological_process											owl:Class	
GO:0033321	biolink:NamedThing	homomethionine metabolic process	The chemical reactions and pathways involving homomethionine, a non-protein amino acid synthesized from methionine via chain elongation.	tmpzr1t_l9r_go_relaxed.owl	homomethionine metabolism													biological_process											owl:Class	
GO:0009037	biolink:NamedThing	tyrosine-based site-specific recombinase activity	Catalysis of the formation of new phosphodiester bonds between a pair of short, unique DNA target sequences; occurs through a phosphotyrosyl intermediate in which the target sequence is first cleaved by the nucleophilic attack by a tyrosine in the active site.	tmpzr1t_l9r_go_relaxed.owl	tyrosine recombinase|site-specific tyrosine recombinase activity													molecular_function											owl:Class	
GO:0009009	biolink:NamedThing	site-specific recombinase activity	Catalysis of the formation of new phosphodiester bonds between a pair of short, unique target DNA sequences.	tmpzr1t_l9r_go_relaxed.owl	RecA-family recombinase activity	https://github.com/geneontology/go-ontology/issues/3917				Note that this term is not a child of 'recombinase activity ; GO:0000150' because the latter represents activities that do not break or form phosphodiester bonds.								molecular_function											owl:Class	
GO:0019166	biolink:NamedThing	trans-2-enoyl-CoA reductase (NADPH) activity	Catalysis of the reaction: acyl-CoA + NADP+ = trans-2,3-dehydroacyl-CoA + NADPH + H+.	tmpzr1t_l9r_go_relaxed.owl	reductase, trans-enoyl coenzyme A|acyl-CoA:NADP+ trans-2-oxidoreductase activity|NADPH-dependent trans-2-enoyl-CoA reductase activity				Reactome:R-HSA-8952873|Reactome:R-HSA-6786720|MetaCyc:TRANSENOYLCOARED-RXN|Reactome:R-HSA-6809810|RHEA:33763|EC:1.3.1.38									molecular_function											owl:Class	
GO:0046709	biolink:NamedThing	IDP catabolic process	The chemical reactions and pathways resulting in the breakdown of IDP, inosine 5'-diphosphate.	tmpzr1t_l9r_go_relaxed.owl	IDP catabolism|IDP breakdown|IDP degradation													biological_process											owl:Class	
GO:0046707	biolink:NamedThing	IDP metabolic process	The chemical reactions and pathways involving IDP, inosine 5'-diphosphate.	tmpzr1t_l9r_go_relaxed.owl	IDP metabolism													biological_process											owl:Class	
GO:0005375	biolink:NamedThing	copper ion transmembrane transporter activity	Enables the transfer of copper (Cu) ions from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	intracellular copper ion transporter|copper uptake transmembrane transporter activity|plasma membrane copper transporter				RHEA:28703|Reactome:R-HSA-437300							GO:0015088|GO:0005379|GO:0005378|GO:0005380		molecular_function											owl:Class	
GO:0051359	biolink:NamedThing	peptide cross-linking via 2-imino-methionine 5-imidazolinone glycine	The formation of the fluorescent protein FP611 chromophore cross-link from the alpha-carboxyl carbon of residue n, a methionine, to the alpha-amino nitrogen of residue n+2, a glycine, and a dehydration to form a double bond to the alpha-amino nitrogen of residue n+1. This cross-linking is coupled with a dehydrogenation of residue n+1 to form a double bond between the alpha and beta carbons. This modification is found in the GFP-like fluorescent chromoprotein from the sea anemone Entacmaea quadricolor.	tmpzr1t_l9r_go_relaxed.owl	biosynthetic process of protein-protein cross-link via 2-imino-methionine 5-imidazolinone glycine|biosynthesis of protein-protein cross-link via 2-imino-methionine 5-imidazolinone glycine				RESID:AA0379	See also the biological process term 'peptidyl-tyrosine dehydrogenation ; GO:0018251'.								biological_process											owl:Class	
GO:0018201	biolink:NamedThing	peptidyl-glycine modification	The modification of peptidyl-glycine.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0018275	biolink:NamedThing	N-terminal peptidyl-cysteine acetylation	The acetylation of the N-terminal cysteine of proteins to form the derivative N-acetyl-L-cysteine.	tmpzr1t_l9r_go_relaxed.owl	peptidyl-cysteine N-acetylation				RESID:AA0043							GO:0017191		biological_process											owl:Class	
GO:0018533	biolink:NamedThing	peptidyl-cysteine acetylation	The acetylation of peptidyl-cysteine.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1903316	biolink:NamedThing	positive regulation of nitrogen cycle metabolic process	Any process that activates or increases the frequency, rate or extent of nitrogen cycle metabolic process.	tmpzr1t_l9r_go_relaxed.owl	activation of nitrogen cycle metabolic process|up-regulation of nitrogen cycle metabolic process|upregulation of nitrogen cycle metabolic process|up regulation of nitrogen cycle metabolic process							vw	2014-08-18T12:57:50Z					biological_process											owl:Class	
GO:1904464	biolink:NamedThing	regulation of matrix metallopeptidase secretion	Any process that modulates the frequency, rate or extent of matrix metallopeptidase secretion.	tmpzr1t_l9r_go_relaxed.owl	regulation of MMP secretion|regulation of matrix metalloproteinase secretion							sl	2015-07-09T19:46:17Z					biological_process											owl:Class	
GO:0043179	biolink:NamedThing	rhythmic excitation	Any process involved in the generation of rhythmic, synchronous excitatory synaptic inputs in a neural circuit.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0060024	biolink:NamedThing	rhythmic synaptic transmission	Any process involved in the generation of rhythmic, synchronous synaptic inputs in a neural circuit.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0098876	biolink:NamedThing	vesicle-mediated transport to the plasma membrane	The directed movement of substances to the plasma membrane in transport vesicles that fuse with the plasma membrane by exocytosis.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0010366	biolink:NamedThing	negative regulation of ethylene biosynthetic process	Any process that stops, prevents, or reduces the frequency, rate or extent of an ethylene biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1900912	biolink:NamedThing	negative regulation of olefin biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of olefin biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of olefin biosynthesis|down-regulation of olefin biosynthetic process|down regulation of olefin anabolism|down regulation of olefin biosynthetic process|downregulation of olefin biosynthesis|inhibition of olefin synthesis|inhibition of olefin biosynthesis|downregulation of olefin biosynthetic process|negative regulation of olefin synthesis|inhibition of olefin biosynthetic process|down-regulation of olefin formation|downregulation of olefin synthesis|downregulation of olefin anabolism|negative regulation of olefin anabolism|down-regulation of olefin anabolism|down regulation of olefin synthesis|down-regulation of olefin biosynthesis|down-regulation of olefin synthesis|negative regulation of olefin formation|downregulation of olefin formation|inhibition of olefin formation|down regulation of olefin formation|down regulation of olefin biosynthesis|inhibition of olefin anabolism							tt	2012-06-13T04:20:30Z					biological_process											owl:Class	
GO:0046932	biolink:NamedThing	sodium-transporting ATP synthase activity, rotational mechanism	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ADP + phosphate + Na+(out) => ATP + H2O + Na+(in), by a rotational mechanism.	tmpzr1t_l9r_go_relaxed.owl	sodium-transporting two-sector ATPase activity|sodium-translocating F-type ATPase activity	https://github.com/geneontology/go-ontology/issues/19380|https://github.com/geneontology/go-ontology/issues/21796			TC:3.A.2.1.2|EC:7.2.2.1|RHEA:58156|RHEA:58158|MetaCyc:3.6.3.15-RXN									molecular_function											owl:Class	
GO:0046829	biolink:NamedThing	negative regulation of RNA import into nucleus	Any process that stops, prevents, or reduces the frequency, rate or extent of the movement of RNA from the cytoplasm into the nucleus.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of RNA import into nucleus|negative regulation of RNA import into cell nucleus|downregulation of RNA import into nucleus|inhibition of RNA import into nucleus|down regulation of RNA import into nucleus|negative regulation of RNA transport from cytoplasm to nucleus|negative regulation of RNA-nucleus import													biological_process											owl:Class	
GO:0046828	biolink:NamedThing	regulation of RNA import into nucleus	Any process that modulates the frequency, rate or extent of movement of RNA from the cytoplasm to the nucleus.	tmpzr1t_l9r_go_relaxed.owl	regulation of RNA-nucleus import|regulation of RNA import into cell nucleus|regulation of RNA transport from cytoplasm to nucleus													biological_process											owl:Class	
GO:0050237	biolink:NamedThing	pyridoxine 4-oxidase activity	Catalysis of the reaction: pyridoxine + O2 = pyridoxal + H2O2.	tmpzr1t_l9r_go_relaxed.owl	pyridoxin 4-oxidase activity|pyridoxol 4-oxidase activity|pyridoxine:oxygen 4-oxidoreductase activity				RHEA:15033|EC:1.1.3.12|MetaCyc:PYRIDOXINE-4-OXIDASE-RXN									molecular_function											owl:Class	
GO:0090727	biolink:NamedThing	positive regulation of brood size	Any process that increases brood size. Brood size is the number of progeny that survive embryogenesis and are cared for at one time.	tmpzr1t_l9r_go_relaxed.owl								tb	2016-12-19T15:07:32Z					biological_process											owl:Class	
GO:0060378	biolink:NamedThing	regulation of brood size	Any process that modulates brood size. Brood size is the number of progeny that survive embryogenesis and are cared for at one time.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1902609	biolink:NamedThing	(R)-2-hydroxy-alpha-linolenic acid biosynthetic process	The chemical reactions and pathways resulting in the formation of (R)-2-hydroxy-alpha-linolenic acid.	tmpzr1t_l9r_go_relaxed.owl	(R)-2-hydroxy-alpha-linolenic acid formation|(R)-2-hydroxy-alpha-linolenic acid synthesis|2-hydroxy-octadecatrienoic acid biosynthesis|(R)-2-hydroxy-alpha-linolenic acid biosynthesis|(R)-2-hydroxy-alpha-linolenic acid anabolism							tb	2014-01-08T01:14:03Z					biological_process											owl:Class	
GO:0042759	biolink:NamedThing	long-chain fatty acid biosynthetic process	The chemical reactions and pathways resulting in the formation of long-chain fatty acids, any fatty acid with a chain length between C13 and C22.	tmpzr1t_l9r_go_relaxed.owl	long-chain fatty acid biosynthesis|long-chain fatty acid synthesis|long-chain fatty acid anabolism|long-chain fatty acid formation													biological_process											owl:Class	
GO:0036025	biolink:NamedThing	protein C inhibitor-TMPRSS11E complex	A heterodimeric protein complex that contains protein C inhibitor (SERPINA5) and transmembrane protease serine 11E (TMPRSS11E); formation of the complex inhibits the serine protease activity of transmembrane protease serine 11E.	tmpzr1t_l9r_go_relaxed.owl	serpin A5-TMPRSS11E complex|PCI-TMPRSS11E complex|SERPINA5-TMPRSS11E complex|protein C inhibitor-transmembrane protease serine 11E complex|plasma serine protease inhibitor-TMPRSS11E complex							bf	2011-10-19T01:29:08Z					cellular_component											owl:Class	
GO:1900775	biolink:NamedThing	fumiquinazoline biosynthetic process	The chemical reactions and pathways resulting in the formation of fumiquinazoline.	tmpzr1t_l9r_go_relaxed.owl	fumiquinazoline synthesis|fumiquinazolines anabolism|fumiquinazolines formation|fumiquinazolines synthesis|fumiquinazolines biosynthesis|fumiquinazoline anabolism|fumiquinazoline biosynthesis|fumiquinazolines biosynthetic process|fumiquinazoline formation							di	2012-06-04T09:29:54Z					biological_process											owl:Class	
GO:0033735	biolink:NamedThing	aspartate dehydrogenase activity	Catalysis of the reaction: L-aspartate + H2O + NAD(P)+ = oxaloacetate + NH3 + NAD(P)H + H+.	tmpzr1t_l9r_go_relaxed.owl	NADH2-dependent aspartate dehydrogenase activity|NADP+-dependent aspartate dehydrogenase activity|NAD-dependent aspartate dehydrogenase activity|L-aspartate:NAD(P)+ oxidoreductase (deaminating) activity				EC:1.4.1.21|KEGG_REACTION:R07164|KEGG_REACTION:R07165|MetaCyc:1.4.1.21-RXN									molecular_function											owl:Class	
GO:0033393	biolink:NamedThing	homogalacturonan catabolic process	The chemical reactions and pathways resulting in the breakdown of homogalacturonan, a pectidic polymer, characterized by a backbone of 1,4-linked alpha-D-GalpA residues that can be methyl-esterified at C-6 and carry acetyl groups on O-2 and O-3.	tmpzr1t_l9r_go_relaxed.owl	homogalacturonan catabolism|homogalacturonan degradation|homogalacturonan breakdown				MetaCyc:PWY-1081									biological_process											owl:Class	
GO:0010674	biolink:NamedThing	negative regulation of transcription from RNA polymerase II promoter involved in meiotic cell cycle	Any process that decreases the frequency, rate or extent of transcription from an RNA polymerase II promoter as part of the meiotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl	stimulation of meiosis by negative regulation of transcription from RNA polymerase II promoter|upregulation of meiosis by negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter, meiotic|positive regulation of meiosis by negative regulation of transcription from RNA polymerase II promoter|up regulation of meiosis by negative regulation of transcription from RNA polymerase II promoter|activation of meiosis by negative regulation of transcription from RNA polymerase II promoter|up-regulation of meiosis by negative regulation of transcription from RNA polymerase II promoter							dgf	2012-05-01T08:39:58Z			GO:1900475		biological_process											owl:Class	
GO:0051038	biolink:NamedThing	negative regulation of transcription involved in meiotic cell cycle	Any process that stops, prevents, or reduces the frequency, rate or extent of transcription involved in the meiotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of meiotic transcription|down-regulation of transcription during meiosis|down regulation of transcription during meiosis|downregulation of transcription during meiosis|inhibition of transcription during meiosis|negative regulation of transcription, meiotic|meiotic repression of transcription													biological_process											owl:Class	
GO:0017117	biolink:NamedThing	single-stranded DNA-dependent ATP-dependent DNA helicase complex	A protein complex that possesses single-stranded DNA-dependent DNA helicase activity.	tmpzr1t_l9r_go_relaxed.owl	ssDNA-dependent ATP-dependent DNA helicase complex													cellular_component											owl:Class	
GO:0010905	biolink:NamedThing	negative regulation of UDP-glucose catabolic process	Any process that decreases the rate, frequency or extent of UDP-glucose catabolism. UDP-glucose catabolic processes are the chemical reactions and pathways resulting in the breakdown of UDP-glucose, uridinediphosphoglucose, a substance composed of glucose in glycosidic linkage with uridine diphosphate.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of UDP-glucose catabolism													biological_process											owl:Class	
GO:0047016	biolink:NamedThing	cholest-5-ene-3-beta,7-alpha-diol 3-beta-dehydrogenase activity	Catalysis of the reaction: NAD+ + 7-alpha-hydroxycholesterol = NADH + H+ + 7-alpha-hydroxycholest-4-en-3-one.	tmpzr1t_l9r_go_relaxed.owl	cholest-5-ene-3beta,7alpha-diol:NAD+ 3-oxidoreductase activity|3beta-hydroxy-delta5-C27-steroid oxidoreductase|cholest-5-ene-3beta,7alpha-diol 3beta-dehydrogenase activity|3-beta-hydroxy-Delta(5)-C(27)-steroid oxidoreductase activity				MetaCyc:1.1.1.181-RXN|RHEA:11896|EC:1.1.1.181									molecular_function											owl:Class	
GO:0010652	biolink:NamedThing	positive regulation of cell communication by chemical coupling	Any process that increases the frequency, rate or extent of cell communication via chemical coupling. Cell communication by chemical coupling is the process that mediates signaling interactions between one cell and another cell by the transfer of small, water-soluble molecules or metabolites between their adjacent cytoplasms via intercellular protein channels.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0036098	biolink:NamedThing	male germ-line stem cell population maintenance	The process by which an organism or tissue maintains a population of male germ-line stem cells.	tmpzr1t_l9r_go_relaxed.owl								bf	2012-01-26T01:58:10Z					biological_process											owl:Class	
GO:0030718	biolink:NamedThing	germ-line stem cell population maintenance	Any process by which an organism or tissue maintains a population of germ-line stem cells.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0045501	biolink:NamedThing	regulation of sevenless signaling pathway	Any process that modulates the frequency, rate or extent of the sevenless signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	regulation of sevenless signalling pathway|regulation of sev signaling pathway													biological_process											owl:Class	
GO:1901418	biolink:NamedThing	positive regulation of response to ethanol	Any process that activates or increases the frequency, rate or extent of response to ethanol.	tmpzr1t_l9r_go_relaxed.owl	activation of response to ethanol|up regulation of response to ethanol|up-regulation of response to ethanol|upregulation of response to ethanol							tt	2012-10-01T16:49:51Z					biological_process											owl:Class	
GO:0071502	biolink:NamedThing	cellular response to temperature stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a temperature stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to thermal stimulus							mah	2009-12-18T02:56:45Z					biological_process											owl:Class	
GO:0016325	biolink:NamedThing	oocyte microtubule cytoskeleton organization	Formation and maintenance of a polarized microtubule array originating from a microtubule-organizing center (MTOC) in the oocyte. An example of this is found in Drosophila melanogaster.	tmpzr1t_l9r_go_relaxed.owl	oocyte microtubule cytoskeleton organisation											GO:0048130		biological_process											owl:Class	
GO:0030951	biolink:NamedThing	establishment or maintenance of microtubule cytoskeleton polarity	Any cellular process that results in the specification, formation or maintenance of polarized microtubule-based cytoskeletal structures.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0072021	biolink:NamedThing	ascending thin limb development	The process whose specific outcome is the progression of an ascending thin limb over time, from its formation to the mature structure. The ascending thin limb is a segment of a nephron tubule lying in the inner medulla that is permeable to ions but not to water and has a simple epithelium; active transepithelial solute transport is absent.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-01-25T02:37:13Z					biological_process											owl:Class	
GO:0099070	biolink:NamedThing	static microtubule bundle	A microtubule bundle that has a constant length, and in which microtubule sliding does not take place.	tmpzr1t_l9r_go_relaxed.owl	Q-MT bundle|quiescent cell MT bundle|quiescent cell microtubule bundle					In fission yeast, quiescent cells contain only static microtubule bundles.								cellular_component											owl:Class	
GO:0097427	biolink:NamedThing	microtubule bundle	An arrangement of closely apposed microtubules running parallel to each other.	tmpzr1t_l9r_go_relaxed.owl	microtubule fascicle				NIF_Subcellular:sao1872343973			pr	2012-11-07T15:01:27Z					cellular_component											owl:Class	
GO:1905641	biolink:NamedThing	cellular response to acetaldehyde	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acetaldehyde stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2016-11-04T15:07:26Z					biological_process											owl:Class	
GO:0061255	biolink:NamedThing	mesonephric glomerular parietal epithelial cell fate commitment	The process in which the developmental fate of a cell becomes restricted such that it will develop into a mesonephric glomerular parietal epithelial cell. Mesonephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. These cells may also give rise to podocytes.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-08-30T01:33:52Z					biological_process											owl:Class	
GO:0102653	biolink:NamedThing	gibberellin A51,2-oxoglutarate:oxygen oxidoreductase activity	Catalysis of the reaction: gibberellin A51 + 2-oxoglutarate + O2 <=> H+ + gibberellin A51-catabolite + succinate + carbon dioxide + H2O.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-172									molecular_function											owl:Class	
GO:1900493	biolink:NamedThing	positive regulation of [4Fe-4S] cluster assembly	Any process that activates or increases the frequency, rate or extent of [4Fe-4S] cluster assembly.	tmpzr1t_l9r_go_relaxed.owl	up regulation of 4Fe-4S cluster assembly|activation of [4Fe-4S] cluster biosynthetic process|up-regulation of [4Fe-4S] cluster assembly|up regulation of [4Fe-4S] cluster assembly|upregulation of [4Fe-4S] cluster assembly|positive regulation of 4Fe-4S cluster assembly|up regulation of [4Fe-4S] cluster biosynthetic process|up-regulation of 4Fe-4S cluster assembly|positive regulation of [4Fe-4S] cluster biosynthetic process|activation of [4Fe-4S] cluster assembly|upregulation of 4Fe-4S cluster assembly|activation of 4Fe-4S cluster assembly|up-regulation of [4Fe-4S] cluster biosynthetic process|upregulation of [4Fe-4S] cluster biosynthetic process							tt	2012-05-02T03:49:10Z					biological_process											owl:Class	
GO:0051661	biolink:NamedThing	maintenance of centrosome location	Any process in which a centrosome is maintained in a specific location within a cell and prevented from moving elsewhere.	tmpzr1t_l9r_go_relaxed.owl	maintenance of centrosome localization													biological_process											owl:Class	
GO:0051642	biolink:NamedThing	centrosome localization	Any process in which a centrosome is transported to, and/or maintained in, a specific location within the cell.	tmpzr1t_l9r_go_relaxed.owl	centrosome localisation|establishment and maintenance of centrosome localization													biological_process											owl:Class	
GO:0048137	biolink:NamedThing	spermatocyte division	The meiotic divisions undergone by the primary and secondary spermatocytes to produce haploid spermatids.	tmpzr1t_l9r_go_relaxed.owl	spermatocyte cell division													biological_process											owl:Class	
GO:0031927	biolink:NamedThing	pyridoxamine transmembrane transporter activity	Enables the transfer of pyridoxamine from one side of a membrane to the other. Pyridoxamine, 4-(aminomethyl)-5-(hydroxymethyl)-2-methylpyridin-3-ol, is one of the vitamin B6 compounds. Pyridoxal, pyridoxamine and pyridoxine are collectively known as vitamin B6, and are efficiently converted to the biologically active form of vitamin B6, pyridoxal phosphate.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1901646	biolink:NamedThing	negative regulation of synoviocyte proliferation	Any process that stops, prevents or reduces the frequency, rate or extent of synoviocyte proliferation.	tmpzr1t_l9r_go_relaxed.owl	down regulation of synoviocyte proliferation|downregulation of synoviocyte proliferation|down-regulation of synoviocyte proliferation|inhibition of synoviocyte proliferation							hjd	2012-11-16T20:16:27Z					biological_process											owl:Class	
GO:1901645	biolink:NamedThing	regulation of synoviocyte proliferation	Any process that modulates the frequency, rate or extent of synoviocyte proliferation.	tmpzr1t_l9r_go_relaxed.owl								hjd	2012-11-16T20:16:23Z					biological_process											owl:Class	
GO:1900911	biolink:NamedThing	regulation of olefin biosynthetic process	Any process that modulates the frequency, rate or extent of olefin biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of olefin anabolism|regulation of olefin formation|regulation of olefin biosynthesis|regulation of olefin synthesis							tt	2012-06-13T04:20:08Z					biological_process											owl:Class	
GO:0062133	biolink:NamedThing	negative regulation of L-glutamine biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of L-glutamine biosynthesis.	tmpzr1t_l9r_go_relaxed.owl								dph	2019-06-27T13:47:21Z					biological_process											owl:Class	
GO:0045985	biolink:NamedThing	positive regulation of pyrimidine nucleobase metabolic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving pyrimidine nucleobases.	tmpzr1t_l9r_go_relaxed.owl	activation of pyrimidine base metabolic process|upregulation of pyrimidine base metabolic process|positive regulation of pyrimidine base metabolic process|positive regulation of pyrimidine base metabolism|stimulation of pyrimidine base metabolic process|up regulation of pyrimidine base metabolic process|up-regulation of pyrimidine base metabolic process													biological_process											owl:Class	
GO:0045906	biolink:NamedThing	negative regulation of vasoconstriction	Any process that stops, prevents, or reduces the frequency, rate or extent of vasoconstriction.	tmpzr1t_l9r_go_relaxed.owl	downregulation of vasoconstriction|inhibition of vasoconstriction|down-regulation of vasoconstriction|down regulation of vasoconstriction													biological_process											owl:Class	
GO:0036155	biolink:NamedThing	acylglycerol acyl-chain remodeling	Remodeling the acyl chains of an acylglycerol, through sequential deacylation and re-acylation reactions, to generate an acylglycerol containing different types of fatty acid acyl chains.	tmpzr1t_l9r_go_relaxed.owl	glyceride acyl-chain remodeling							bf	2012-03-14T02:55:00Z					biological_process											owl:Class	
GO:0006639	biolink:NamedThing	acylglycerol metabolic process	The chemical reactions and pathways involving acylglycerol, any mono-, di- or triester of glycerol with (one or more) fatty acids.	tmpzr1t_l9r_go_relaxed.owl	glyceride metabolic process|acylglycerol metabolism|glyceride metabolism													biological_process											owl:Class	
GO:0043267	biolink:NamedThing	negative regulation of potassium ion transport	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of potassium ions (K+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	inhibition of potassium ion transport|negative regulation of potassium transport|transmembrane conductance regulator activity|negative regulation of K+ transport|down-regulation of potassium ion transport|negative regulation of potassium ion conductance|down regulation of potassium ion transport|regulation of potassium conductance|regulation of K+ conductance|downregulation of potassium ion transport													biological_process											owl:Class	
GO:0102060	biolink:NamedThing	endo-alpha-bergamotene synthase activity	Catalysis of the reaction: 2-cis,6-cis-farnesyl diphosphate <=> (-)-endo-alpha-bergamotene + diphosphoric acid.	tmpzr1t_l9r_go_relaxed.owl	endo-alpha-bergamontene synthase activity				RHEA:30471|MetaCyc:RXN-10482|EC:4.2.3.54									molecular_function											owl:Class	
GO:0061017	biolink:NamedThing	hepatoblast differentiation	The process in which a relatively unspecialized cell acquires specialized features of a hepatoblast. A hepatoblast is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into hepatocytes and cholangiocytes.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-02-02T09:08:03Z					biological_process											owl:Class	
GO:1903136	biolink:NamedThing	cuprous ion binding	Binding to a cuprous ion, copper(1+).	tmpzr1t_l9r_go_relaxed.owl	Cu(+) binding|Cu(I) binding|copper(1+) binding							bf	2014-06-26T14:38:23Z					molecular_function											owl:Class	
GO:0018221	biolink:NamedThing	peptidyl-serine palmitoylation	The covalent attachment of a palmitoyl group to an oxygen (O) atom in a serine residue to form peptidyl-O-palmitoyl-L-serine.	tmpzr1t_l9r_go_relaxed.owl	peptidyl-serine O-palmitoylation				RESID:AA0080	Palmitoylation of a non-terminal serine residue always occurs on an oxygen (O) atom.								biological_process											owl:Class	
GO:0018345	biolink:NamedThing	protein palmitoylation	The covalent attachment of a palmitoyl group to a protein.	tmpzr1t_l9r_go_relaxed.owl	protein amino acid palmitoylation											GO:0018318|GO:0018349		biological_process											owl:Class	
GO:0005010	biolink:NamedThing	insulin-like growth factor-activated receptor activity	Combining with insulin-like growth factor and transmitting the signal across the plasma membrane to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	insulin-like growth factor receptor activity|IGF receptor activity|IGF-activated receptor activity					Note that this term represents an activity and not a gene product, and should only be used when the receptor binds the ligand IGF. For receptors that bind other growth factors, consider annotating to other terms under 'transmembrane signaling receptor activity ; GO:0004888.								molecular_function											owl:Class	
GO:2000412	biolink:NamedThing	positive regulation of thymocyte migration	Any process that activates or increases the frequency, rate or extent of thymocyte migration.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of immature T-cell migration|positive regulation of thymic lymphocyte migration|positive regulation of immature T cell migration|positive regulation of immature T lymphocyte migration|positive regulation of immature T-lymphocyte migration							mah	2011-02-23T01:34:23Z					biological_process											owl:Class	
GO:0072339	biolink:NamedThing	cellular lactam biosynthetic process	The chemical reactions and pathways resulting in the formation of lactams, any cyclic amides of amino carboxylic acids, having a 1-azacycloalkan-2-one structure, or analogues having unsaturation or heteroatoms replacing one or more carbon atoms of the ring.	tmpzr1t_l9r_go_relaxed.owl	cellular lactam formation|cellular lactam biosynthesis|cellular lactam synthesis|cellular lactam anabolism							mah	2010-11-04T04:33:01Z					biological_process											owl:Class	
GO:1901840	biolink:NamedThing	negative regulation of RNA polymerase I regulatory region sequence-specific DNA binding	Any process that stops, prevents or reduces the frequency, rate or extent of RNA polymerase I regulatory region sequence-specific DNA binding.	tmpzr1t_l9r_go_relaxed.owl	inhibition of RNA polymerase I regulatory region sequence-specific DNA binding|downregulation of RNA polymerase I regulatory region sequence-specific DNA binding|down regulation of RNA polymerase I regulatory region sequence-specific DNA binding|down-regulation of RNA polymerase I regulatory region sequence-specific DNA binding							sart	2013-01-23T10:24:37Z					biological_process											owl:Class	
GO:0048872	biolink:NamedThing	homeostasis of number of cells	Any biological process involved in the maintenance of the steady-state number of cells within a population of cells.	tmpzr1t_l9r_go_relaxed.owl	cell population homeostasis|homeostasis of cell number													biological_process											owl:Class	
GO:0006246	biolink:NamedThing	dTDP catabolic process	The chemical reactions and pathways resulting in the breakdown of dTDP, deoxyribosylthymine diphosphate.	tmpzr1t_l9r_go_relaxed.owl	dTDP catabolism|dTDP degradation|dTDP breakdown													biological_process											owl:Class	
GO:0010268	biolink:NamedThing	brassinosteroid homeostasis	Any process involved in the maintenance of an internal steady state of brassinosteroids within an organism or cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0055088	biolink:NamedThing	lipid homeostasis	Any process involved in the maintenance of an internal steady state of lipid within an organism or cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0060857	biolink:NamedThing	establishment of glial blood-brain barrier	Establishment of the glial barrier between the blood and the brain. The glial cells in the brain are packed tightly together preventing the passage of most molecules from the blood into the brain. Only lipid soluble molecules or those that are actively transported can pass through the blood-brain barrier.	tmpzr1t_l9r_go_relaxed.owl	establishment of glial BBB|establishment of glial blood/brain barrier							dph	2009-08-12T12:17:51Z					biological_process											owl:Class	
GO:0090012	biolink:NamedThing	negative regulation of transforming growth factor beta receptor signaling pathway involved in primitive streak formation	Any process that stops, prevents, or reduces the frequency, rate or extent of any TGF-beta receptor signaling pathway that contributes to the formation of the primitive streak.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of transforming growth factor beta receptor signalling pathway involved in primitive streak formation							tb	2009-07-29T10:51:57Z					biological_process											owl:Class	
GO:0062095	biolink:NamedThing	endoplasmic reticulum-peroxisome tethering	The attachment of an endoplasmic reticulum membrane to a peroxisome via molecular tethers that physically bridge the two membranes and attach them to each other.	tmpzr1t_l9r_go_relaxed.owl								dph	2018-11-21T13:28:50Z					biological_process											owl:Class	
GO:0060151	biolink:NamedThing	peroxisome localization	Any process in which a peroxisome is transported to, and/or maintained in, a specific location. A peroxisome is a small membrane-bounded organelle that uses dioxygen (O2) to oxidize organic molecules.	tmpzr1t_l9r_go_relaxed.owl	peroxisome localisation													biological_process											owl:Class	
GO:0008616	biolink:NamedThing	queuosine biosynthetic process	The chemical reactions and pathways resulting in the formation of queuosines, a series of nucleosides found in tRNA and having an additional pentenyl ring added via an NH group to the methyl group of 7-methylguanosine. The pentenyl ring may carry other substituents.	tmpzr1t_l9r_go_relaxed.owl	queuosine formation|queuosine synthesis|queuosine anabolism|queuosine biosynthesis													biological_process											owl:Class	
GO:0050779	biolink:NamedThing	RNA destabilization	Any process that decreases the stability of an RNA molecule, making it more vulnerable to degradative processes.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0021979	biolink:NamedThing	hypothalamus cell differentiation	The differentiation of cells that will contribute to the structure and function of the hypothalamus.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0032276	biolink:NamedThing	regulation of gonadotropin secretion	Any process that modulates the frequency, rate or extent of the regulated release of a gonadotropin.	tmpzr1t_l9r_go_relaxed.owl	regulation of gonadotrophin secretion													biological_process											owl:Class	
GO:0070474	biolink:NamedThing	positive regulation of uterine smooth muscle contraction	Any process that increases the frequency, rate or extent of uterine smooth muscle contraction.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of myometrial contraction|positive regulation of myometrial smooth muscle contraction|positive regulation of myometrium contraction|activation of uterine smooth muscle contraction|upregulation of uterine smooth muscle contraction|up-regulation of uterine smooth muscle contraction|stimulation of uterine smooth muscle contraction|up regulation of uterine smooth muscle contraction													biological_process											owl:Class	
GO:0070472	biolink:NamedThing	regulation of uterine smooth muscle contraction	Any process that modulates the frequency, rate or extent of uterine smooth muscle contraction.	tmpzr1t_l9r_go_relaxed.owl	regulation of myometrial contraction|regulation of myometrium contraction|regulation of myometrial smooth muscle contraction													biological_process											owl:Class	
GO:2000162	biolink:NamedThing	negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis	Any process that stops, prevents, or reduces the frequency, rate or extent of planar cell polarity pathway involved in cardiac right atrium morphogenesis.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-10-05T01:05:24Z					biological_process											owl:Class	
GO:0060162	biolink:NamedThing	negative regulation of phospholipase C-activating dopamine receptor signaling pathway	Any process that stops, prevents, or reduces the frequency, rate or extent of the dopamine receptor, phospholipase C activating pathway.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of phospholipase C-activating dopamine receptor signalling pathway|negative regulation of dopamine receptor, phospholipase C activating pathway													biological_process											owl:Class	
GO:1900737	biolink:NamedThing	negative regulation of phospholipase C-activating G protein-coupled receptor signaling pathway	Any process that stops, prevents or reduces the frequency, rate or extent of phospholipase C-activating G protein-coupled receptor signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	downregulation of G protein signaling, coupled to IP3 second messenger (phospholipase C activating)|negative regulation of G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)|downregulation of activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger|inhibition of G-protein coupled receptor signaling pathway coupled to IP3 second messenger|down-regulation of G-protein signalling, coupled to IP3 second messenger (phospholipase C activating)|inhibition of PLC-activating GPCR signaling pathway|negative regulation of phospholipase C-activating dopamine receptor signaling pathway|negative regulation of G-protein coupled receptor signaling pathway coupled to IP3 second messenger|negative regulation of G protein signaling, coupled to IP3 second messenger (phospholipase C activating)|down regulation of phospholipase C-activating dopamine receptor signaling pathway|inhibition of phospholipase C-activating G-protein coupled receptor signaling pathway|down regulation of activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger|downregulation of phospholipase C-activating G-protein coupled receptor signaling pathway|down regulation of phospholipase C-activating G-protein coupled receptor signaling pathway|inhibition of G protein signalling, coupled to IP3 second messenger (phospholipase C activating)|down regulation of G-protein signalling, coupled to IP3 second messenger (phospholipase C activating)|negative regulation of activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger|downregulation of G-protein coupled receptor signaling pathway coupled to IP3 second messenger|down-regulation of PLC-activating GPCR signaling pathway|down regulation of G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)|down regulation of G-protein coupled receptor signaling pathway coupled to IP3 second messenger|negative regulation of PLC-activating GPCR signaling pathway|inhibition of G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)|inhibition of G-protein signalling, coupled to IP3 second messenger (phospholipase C activating)|down-regulation of phospholipase C-activating G-protein coupled receptor signaling pathway|down-regulation of G protein signalling, coupled to IP3 second messenger (phospholipase C activating)|down-regulation of G-protein coupled receptor signaling pathway coupled to IP3 second messenger|downregulation of phospholipase C-activating dopamine receptor signaling pathway|downregulation of PLC-activating GPCR signaling pathway|down regulation of PLC-activating GPCR signaling pathway|down regulation of G protein signaling, coupled to IP3 second messenger (phospholipase C activating)|down regulation of G protein signalling, coupled to IP3 second messenger (phospholipase C activating)|negative regulation of phospholipase C-activating G-protein coupled receptor signaling pathway|downregulation of G protein signalling, coupled to IP3 second messenger (phospholipase C activating)|inhibition of activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger|down-regulation of phospholipase C-activating dopamine receptor signaling pathway|inhibition of G protein signaling, coupled to IP3 second messenger (phospholipase C activating)|down-regulation of activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger|down-regulation of G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)|down-regulation of G protein signaling, coupled to IP3 second messenger (phospholipase C activating)|downregulation of G-protein signalling, coupled to IP3 second messenger (phospholipase C activating)|downregulation of G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)|negative regulation of G-protein signalling, coupled to IP3 second messenger (phospholipase C activating)|inhibition of phospholipase C-activating dopamine receptor signaling pathway|negative regulation of G protein signalling, coupled to IP3 second messenger (phospholipase C activating)							rl	2012-05-28T10:07:48Z					biological_process											owl:Class	
GO:0015685	biolink:NamedThing	ferric-enterobactin import into cell	A process in which ferric-enterobactin, the iron-bound form of the siderophore enterobactin, is transported into the cell by specific cell surface receptors.	tmpzr1t_l9r_go_relaxed.owl	ferric-enterobactin transport													biological_process											owl:Class	
GO:1901678	biolink:NamedThing	iron coordination entity transport	The directed movement of an iron coordination entity into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl								pr	2012-11-22T15:43:15Z					biological_process											owl:Class	
GO:0072573	biolink:NamedThing	tolerance induction to lipopolysaccharide	Tolerance induction directed at lipopolysaccharide antigens.	tmpzr1t_l9r_go_relaxed.owl	tolerance induction to endotoxin|tolerance induction to LPS							mah	2011-02-02T03:05:19Z					biological_process											owl:Class	
GO:0090226	biolink:NamedThing	regulation of microtubule nucleation by Ran protein signal transduction	Any series of molecular signals in which a Ran GTPase relays one or more of the signals resulting in the modulation of the rate, frequency or extent of microtubule nucleation.	tmpzr1t_l9r_go_relaxed.owl								tb	2010-01-13T11:35:31Z					biological_process											owl:Class	
GO:0034959	biolink:NamedThing	endothelin maturation	The process leading to the attainment of the full functional capacity of endothelin by conversion of Big-endothelin substrate into mature endothelin.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/15384												biological_process											owl:Class	
GO:0070087	biolink:NamedThing	chromo shadow domain binding	Binding to a chromo shadow domain, a protein domain that is distantly related, and found in association with, the chromo domain.	tmpzr1t_l9r_go_relaxed.owl	chromoshadow domain binding													molecular_function											owl:Class	
GO:1900440	biolink:NamedThing	regulation of filamentous growth of a population of unicellular organisms in response to neutral pH	Any process that modulates the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to neutral pH.	tmpzr1t_l9r_go_relaxed.owl								di	2012-04-25T05:55:48Z					biological_process											owl:Class	
GO:0060548	biolink:NamedThing	negative regulation of cell death	Any process that decreases the rate or frequency of cell death. Cell death is the specific activation or halting of processes within a cell so that its vital functions markedly cease, rather than simply deteriorating gradually over time, which culminates in cell death.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-04-13T01:56:10Z					biological_process											owl:Class	
GO:0006499	biolink:NamedThing	N-terminal protein myristoylation	The covalent attachment of a myristoyl group to the N-terminal amino acid residue of a protein.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0006498	biolink:NamedThing	N-terminal protein lipidation	The covalent attachment of a lipid group to the amino terminus of a protein.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0008362	biolink:NamedThing	chitin-based embryonic cuticle biosynthetic process	Synthesis, including the chemical reactions and pathways resulting in the formation of chitin and other components, and deposition of a chitin-based embryonic cuticle by the underlying epidermal epithelium. This tough, waterproof cuticle layer is essential to provide structural integrity of the larval body. An example of this is found in Drosophila melanogaster.	tmpzr1t_l9r_go_relaxed.owl	embryonic cuticle biosynthetic process|embryonic cuticle formation|embryonic cuticle synthesis|embryonic cuticle anabolism													biological_process											owl:Class	
GO:0040003	biolink:NamedThing	chitin-based cuticle development	Synthesis and deposition of a chitin-based noncellular, hardened, or membranous secretion from an epithelial sheet. An example of this process is found in Drosophila melanogaster.	tmpzr1t_l9r_go_relaxed.owl	chitin-based cuticle anabolism|chitin-based cuticle synthesis|chitin-based cuticle formation|chitin-based cuticle biosynthetic process													biological_process											owl:Class	
GO:0004835	biolink:NamedThing	tubulin-tyrosine ligase activity	Catalysis of the reaction: ATP + detyrosinated alpha-tubulin + L-tyrosine = alpha-tubulin + ADP + phosphate.	tmpzr1t_l9r_go_relaxed.owl	TTL activity|alpha-tubulin:L-tyrosine ligase (ADP-forming)|tubulinyl-tyrosine ligase activity				RHEA:17605|MetaCyc:6.3.2.25-RXN|EC:6.3.2.25|Reactome:R-HSA-8955706									molecular_function											owl:Class	
GO:0042855	biolink:NamedThing	eugenol biosynthetic process	The chemical reactions and pathways resulting in the formation of eugenol, a colorless, aromatic, liquid hydrocarbon (C10H12O2) found in clove oil.	tmpzr1t_l9r_go_relaxed.owl	4-allyl-2-methoxyphenol biosynthesis|eugenol anabolism|4-allyl-2-methoxyphenol biosynthetic process|eugenol biosynthesis|eugenol formation|eugenol synthesis|eugenic acid biosynthetic process|eugenic acid biosynthesis													biological_process											owl:Class	
GO:0006624	biolink:NamedThing	vacuolar protein processing	Protein processing that takes place in the vacuole. Most protein processing in the vacuole represents proteolytic cleavage of precursors to form active enzymes.	tmpzr1t_l9r_go_relaxed.owl	vacuolar proteolysis|vacuolar protein maturation													biological_process											owl:Class	
GO:0034653	biolink:NamedThing	retinoic acid catabolic process	The chemical reactions and pathways resulting in the breakdown of retinoic acid, one of the three components that makes up vitamin A.	tmpzr1t_l9r_go_relaxed.owl	retinoic acid catabolism|retinoic acid degradation|vitamin A1 acid catabolic process|retinoic acid breakdown													biological_process											owl:Class	
GO:0106161	biolink:NamedThing	positive regulation of small RNA loading onto RISC	Any process that activates or increases the frequency, rate or extent of small RNA loading onto RISC.	tmpzr1t_l9r_go_relaxed.owl								hjd	2018-11-30T15:45:53Z					biological_process											owl:Class	
GO:0106159	biolink:NamedThing	regulation of small RNA loading onto RISC	Any process that modulates the frequency, rate or extent small RNA loading onto RISC.	tmpzr1t_l9r_go_relaxed.owl								hjd	2018-11-30T15:38:50Z					biological_process											owl:Class	
GO:0017009	biolink:NamedThing	protein-phycocyanobilin linkage	The linkage of the chromophore phycocyanobilin to phycocyanin or allophycocyanin.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0131									biological_process											owl:Class	
GO:2000571	biolink:NamedThing	regulation of interleukin-4-dependent isotype switching to IgE isotypes	Any process that modulates the frequency, rate or extent of interleukin-4-dependent isotype switching to IgE isotypes.	tmpzr1t_l9r_go_relaxed.owl	regulation of IL-4-dependent isotype switching to IgE isotypes							ebc	2011-04-03T09:20:11Z					biological_process											owl:Class	
GO:0034130	biolink:NamedThing	toll-like receptor 1 signaling pathway	Any series of molecular signals generated as a consequence of binding to toll-like receptor 1.	tmpzr1t_l9r_go_relaxed.owl	TLR1 signaling pathway|toll-like receptor 1 signalling pathway													biological_process											owl:Class	
GO:0097104	biolink:NamedThing	postsynaptic membrane assembly	The aggregation, arrangement and bonding together of a set of components to form a postsynaptic membrane, a specialized area of membrane facing the presynaptic membrane on the tip of the nerve ending and separated from it by a minute cleft (the synaptic cleft).	tmpzr1t_l9r_go_relaxed.owl	post-synaptic membrane assembly							pr	2011-07-27T01:26:49Z					biological_process											owl:Class	
GO:0071737	biolink:NamedThing	IgG B cell receptor complex	An IgG immunoglobulin complex that is present in the plasma membrane of B cells and is composed of two identical immunoglobulin heavy chains of an IgG isotype and two identical immunoglobulin light chains and a signaling subunit, a heterodimer of the Ig-alpha and Ig-beta proteins.	tmpzr1t_l9r_go_relaxed.owl	surface IgG2b|membrane-bound IgG2c|membrane-bound IgG1|membrane-bound IgG4|surface IgG2c|surface IgG2a|surface IgG|surface IgG1|membrane-bound IgG2|membrane-bound IgG2b|surface IgG2|membrane-bound IgG|membrane-bound IgG2a|surface IgG3|membrane-bound IgG3|surface IgG4					Note that an IgG immunoglobulin complex has the function of antigen binding if a suitable antigen is available. Also, IgG isotypes vary by species.		mah	2010-03-24T01:44:53Z					cellular_component											owl:Class	
GO:0019815	biolink:NamedThing	B cell receptor complex	An immunoglobulin complex that is present in the plasma membrane of B cells and that in its canonical form is composed of two identical immunoglobulin heavy chains and two identical immunoglobulin light chains and a signaling subunit, a heterodimer of the Ig-alpha and Ig-beta proteins.	tmpzr1t_l9r_go_relaxed.owl	B lymphocyte receptor complex|immunoglobulin complex, membrane bound|B-cell receptor complex|antibody|B cell receptor accessory molecule complex|B-lymphocyte receptor complex|BCR complex					Note that an immunoglobulin complex has the function of antigen binding if a suitable antigen is available.						GO:0042570		cellular_component											owl:Class	
GO:1901261	biolink:NamedThing	regulation of sorocarp spore cell differentiation	Any process that modulates the frequency, rate or extent of sorocarp spore cell differentiation.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-08-15T09:44:30Z					biological_process											owl:Class	
GO:0030948	biolink:NamedThing	negative regulation of vascular endothelial growth factor receptor signaling pathway	Any process that stops, prevents, or reduces the frequency, rate or extent of vascular endothelial growth factor receptor signaling pathway activity.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of vascular endothelial growth factor receptor signalling pathway|negative regulation of VEGF receptor signaling pathway|down-regulation of vascular endothelial growth factor receptor signaling pathway|downregulation of vascular endothelial growth factor receptor signaling pathway|down regulation of vascular endothelial growth factor receptor signaling pathway|negative regulation of VEGF receptor signalling pathway|inhibition of vascular endothelial growth factor receptor signaling pathway													biological_process											owl:Class	
GO:0018894	biolink:NamedThing	dibenzo-p-dioxin metabolic process	The chemical reactions and pathways involving dibenzo-p-dioxin, a substance composed of two benzene rings linked by two ether bonds. Dibenzo-p-dioxins are generated as by-products in the manufacturing of herbicides, insecticides, fungicides, paper pulp bleaching, and in incineration, and can accumulate in milk and throughout the food chain, creating significant health concern.	tmpzr1t_l9r_go_relaxed.owl	phenodioxin metabolism|oxanthrene metabolic process|dibenzo-p-dioxin metabolism|oxanthrene metabolism|phenodioxin metabolic process				UM-BBD_pathwayID:dpd									biological_process											owl:Class	
GO:0045760	biolink:NamedThing	positive regulation of action potential	Any process that activates or increases the frequency, rate or extent of action potential creation, propagation or termination. This typically occurs via modulation of the activity or expression of voltage-gated ion channels.	tmpzr1t_l9r_go_relaxed.owl	activation of action potential|up regulation of action potential|stimulation of action potential|upregulation of action potential|up-regulation of action potential													biological_process											owl:Class	
GO:0047557	biolink:NamedThing	3-aci-nitropropanoate oxidase activity	Catalysis of the reaction: 3-aci-nitropropanoate + H(2)O + O(2) = 3-oxopropanoate + H(2)O(2) + nitrite.	tmpzr1t_l9r_go_relaxed.owl	3-aci-nitropropanoate:oxygen oxidoreductase activity|propionate-3-nitronate oxidase activity				EC:1.7.3.5|KEGG_REACTION:R01609|RHEA:22372|MetaCyc:3-ACI-NITROPROPANOATE-OXIDASE-RXN									molecular_function											owl:Class	
GO:0016663	biolink:NamedThing	oxidoreductase activity, acting on other nitrogenous compounds as donors, oxygen as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which a nitrogenous group, excluding NH and NH2 groups, acts as a hydrogen or electron donor and reduces oxygen.	tmpzr1t_l9r_go_relaxed.owl					EC:1.7.3.-									molecular_function											owl:Class	
GO:0062192	biolink:NamedThing	L-rhamnose mutarotase activity	Catalysis of the reaction: alpha-L-rhamnose = beta-L-rhamnose.	tmpzr1t_l9r_go_relaxed.owl					RHEA:25584|EC:5.1.3.32			dph	2019-12-09T16:45:45Z					molecular_function											owl:Class	
GO:0004319	biolink:NamedThing	enoyl-[acyl-carrier-protein] reductase (NADPH, B-specific) activity	Catalysis of the reaction: acyl-[acyl-carrier protein] + NADP+ = trans-2,3-dehydroacyl-[acyl-carrier protein] + NADPH + H+.	tmpzr1t_l9r_go_relaxed.owl	acyl-acyl-carrier-protein:NADP+ oxidoreductase (B-specific)|enoyl acyl-carrier-protein reductase activity|enoyl-[acyl-carrier protein] reductase (NADPH, B-specific) activity|enoyl-ACP reductase (NADPH, B-specific) activity|enoyl-acyl-carrier-protein reductase (NADPH2, B-specific)|enoyl-acyl-carrier-protein reductase (NADPH, B-specific)|NADPH 2-enoyl Co A reductase activity|reductase, enoyl-acyl carrier protein (reduced nicotinamide adenine dinucleotide phosphate)				MetaCyc:ENOYL-ACP-REDUCT-NADPH-RXN|EC:1.3.1.10									molecular_function											owl:Class	
GO:0045605	biolink:NamedThing	negative regulation of epidermal cell differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of epidermal cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of hypodermal cell differentiation|inhibition of epidermal cell differentiation|downregulation of epidermal cell differentiation|down-regulation of epidermal cell differentiation|down regulation of epidermal cell differentiation													biological_process											owl:Class	
GO:0060636	biolink:NamedThing	negative regulation of (1->3)-beta-D-glucan biosynthetic process	Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of 1,3-beta-D-glucan biosynthetic process							dph	2009-05-18T03:24:02Z					biological_process											owl:Class	
GO:0043771	biolink:NamedThing	cytidine kinase activity	Catalysis of the reaction: ATP + cytidine = ADP + CMP.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0071386	biolink:NamedThing	cellular response to corticosterone stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a corticosterone stimulus. Corticosterone is a 21 carbon steroid hormone of the corticosteroid type, produced in the cortex of the adrenal glands. In many species, corticosterone is the principal glucocorticoid, involved in regulation of fuel metabolism, immune reactions, and stress responses.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-12-11T03:57:44Z					biological_process											owl:Class	
GO:1901716	biolink:NamedThing	negative regulation of gamma-aminobutyric acid catabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of gamma-aminobutyric acid catabolic process.	tmpzr1t_l9r_go_relaxed.owl	downregulation of GABA catabolism|down-regulation of gamma-aminobutyric acid breakdown|negative regulation of 4-aminobutanoate catabolism|negative regulation of GABA catabolic process|downregulation of gamma-aminobutyric acid catabolism|down-regulation of 4-aminobutanoate catabolism|inhibition of GABA catabolism|down regulation of 4-aminobutanoate catabolism|down-regulation of 4-aminobutanoate catabolic process|inhibition of gamma-aminobutyric acid catabolism|negative regulation of GABA catabolism|inhibition of gamma-aminobutyric acid degradation|negative regulation of gamma-aminobutyric acid degradation|down regulation of GABA catabolism|down-regulation of gamma-aminobutyric acid catabolism|down regulation of gamma-aminobutyric acid breakdown|negative regulation of gamma-aminobutyric acid catabolism|inhibition of 4-aminobutanoate catabolism|inhibition of gamma-aminobutyric acid breakdown|inhibition of 4-aminobutanoate catabolic process|downregulation of GABA catabolic process|down regulation of GABA catabolic process|inhibition of GABA catabolic process|inhibition of 4-aminobutyrate catabolism|down-regulation of GABA catabolism|downregulation of gamma-aminobutyric acid breakdown|down regulation of gamma-aminobutyric acid catabolism|downregulation of gamma-aminobutyric acid degradation|downregulation of gamma-aminobutyric acid catabolic process|down-regulation of GABA catabolic process|inhibition of gamma-aminobutyric acid catabolic process|down regulation of gamma-aminobutyric acid catabolic process|inhibition of 4-aminobutyrate catabolic process|downregulation of 4-aminobutyrate catabolic process|down regulation of 4-aminobutyrate catabolic process|down-regulation of 4-aminobutyrate catabolic process|down regulation of 4-aminobutyrate catabolism|down-regulation of gamma-aminobutyric acid catabolic process|negative regulation of gamma-aminobutyric acid breakdown|down-regulation of gamma-aminobutyric acid degradation|downregulation of 4-aminobutanoate catabolism|down regulation of gamma-aminobutyric acid degradation|downregulation of 4-aminobutanoate catabolic process|negative regulation of 4-aminobutanoate catabolic process|down regulation of 4-aminobutanoate catabolic process|negative regulation of 4-aminobutyrate catabolic process|down-regulation of 4-aminobutyrate catabolism|downregulation of 4-aminobutyrate catabolism|negative regulation of 4-aminobutyrate catabolism							mcc	2012-12-19T16:13:31Z					biological_process											owl:Class	
GO:0051387	biolink:NamedThing	negative regulation of neurotrophin TRK receptor signaling pathway	Any process that stops, prevents, or reduces the frequency, rate or extent of the neurotrophin TRK receptor signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	inhibition of nerve growth factor receptor signaling pathway|downregulation of nerve growth factor receptor signaling pathway|negative regulation of NGF receptor signalling pathway|negative regulation of nerve growth factor receptor signaling pathway|down regulation of nerve growth factor receptor signaling pathway|down-regulation of nerve growth factor receptor signaling pathway|negative regulation of NGF receptor signaling pathway|negative regulation of nerve growth factor receptor signalling pathway													biological_process											owl:Class	
GO:0051386	biolink:NamedThing	regulation of neurotrophin TRK receptor signaling pathway	Any process that modulates the frequency, rate or extent of the neurotrophin TRK receptor signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	regulation of nerve growth factor receptor signalling pathway|regulation of NGF receptor signalling pathway|regulation of nerve growth factor receptor signaling pathway|regulation of NGF receptor signaling pathway													biological_process											owl:Class	
GO:1902510	biolink:NamedThing	regulation of apoptotic DNA fragmentation	Any process that modulates the frequency, rate or extent of apoptotic DNA fragmentation.	tmpzr1t_l9r_go_relaxed.owl	regulation of DNA fragmentation involved in apoptotic nuclear change|regulation of chromatinolysis|regulation of DNA catabolism during apoptosis|regulation of DNA fragmentation|regulation of DNA catabolic process during apoptosis|regulation of endonucleolytic DNA catabolic process involved in apoptosis					DNA fragmentation in response to apoptotic signals is achieved through the activity of apoptotic nucleases (see GO:0006309 'apoptotic DNA fragmentation'). Gene products involved in compartmentalization of such nucleases and in activation or repression of their enzymatic activity should be annotated to the regulation term GO:1902510 'regulation of apoptotic DNA fragmentation' or to one of its children (see PMID:15723341).		hjd	2013-11-15T18:28:32Z					biological_process											owl:Class	
GO:1903624	biolink:NamedThing	regulation of DNA catabolic process	Any process that modulates the frequency, rate or extent of DNA catabolic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of DNA catabolism|regulation of DNA degradation|regulation of DNA breakdown							sl	2014-11-19T22:36:35Z					biological_process											owl:Class	
GO:0010104	biolink:NamedThing	regulation of ethylene-activated signaling pathway	Any process that modulates the frequency, rate or extent of ethylene (ethene) signal transduction.	tmpzr1t_l9r_go_relaxed.owl	regulation of ethylene mediated signaling pathway|regulation of ethene mediated signalling pathway|regulation of ethene mediated signaling pathway|regulation of ethylene mediated signalling pathway													biological_process											owl:Class	
GO:0070297	biolink:NamedThing	regulation of phosphorelay signal transduction system	Any process that modulates the frequency, rate or extent of signal transduction via a phosphorelay signal transduction system.	tmpzr1t_l9r_go_relaxed.owl	regulation of two-component signal transduction system|regulation of histidyl-aspartyl phosphorelay|regulation of two-component signal transduction system (phosphorelay)													biological_process											owl:Class	
GO:0060949	biolink:NamedThing	cardiac vascular smooth muscle cell fate commitment	The commitment of cells to a cardiac vascular smooth muscle cell fate and its capacity to differentiate into a cardiac vascular smooth muscle cell.	tmpzr1t_l9r_go_relaxed.owl	heart vascular smooth muscle cell fate commitment							dph	2009-09-29T03:02:45Z					biological_process											owl:Class	
GO:0097081	biolink:NamedThing	vascular associated smooth muscle cell fate commitment	The commitment of cells to a vascular smooth muscle cell fate and their capacity to differentiate into vascular smooth muscle cells. A vascular smooth muscle cell is a non-striated, elongated, spindle-shaped cell found lining the blood vessels.	tmpzr1t_l9r_go_relaxed.owl	vascular smooth muscle cell fate commitment							pr	2011-06-20T03:51:52Z					biological_process											owl:Class	
GO:0070339	biolink:NamedThing	response to bacterial lipopeptide	Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bacterial lipopeptide stimulus.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0042723	biolink:NamedThing	thiamine-containing compound metabolic process	The chemical reactions and pathways involving thiamine (vitamin B1), and compounds derived from it.	tmpzr1t_l9r_go_relaxed.owl	thiamine and derivative metabolic process|thiamine-containing compound metabolism|thiamin and derivative metabolic process|thiamin and derivative metabolism|vitamin B1 and derivative metabolism|thiamin-containing compound metabolic process|vitamin B1 and derivative metabolic process|thiamine and derivative metabolism													biological_process											owl:Class	
GO:0046284	biolink:NamedThing	anthocyanin-containing compound catabolic process	The chemical reactions and pathways resulting in the breakdown of anthocyanins, any member of a group of intensely colored soluble glycosides of anthocyanidins.	tmpzr1t_l9r_go_relaxed.owl	anthocyanin catabolic process|anthocyanin breakdown|anthocyanin degradation|anthocyanin catabolism													biological_process											owl:Class	
GO:0046283	biolink:NamedThing	anthocyanin-containing compound metabolic process	The chemical reactions and pathways involving anthocyanins, any member of a group of intensely colored soluble glycosides of anthocyanidins that occur in plants. They are responsible from most of the scarlet, purple, mauve and blue coloring in higher plants, especially of flowers.	tmpzr1t_l9r_go_relaxed.owl	anthocyanin metabolism|anthocyanin metabolic process													biological_process											owl:Class	
GO:0071214	biolink:NamedThing	cellular response to abiotic stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abiotic (non-living) stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to abiotic stress					Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.		mah	2009-12-03T01:02:11Z					biological_process											owl:Class	
GO:0042121	biolink:NamedThing	alginic acid biosynthetic process	The chemical reactions and pathways resulting in the formation of alginic acid, a hydrophilic polysaccharide occurring in, for example, the cell walls of brown algae (brown seaweeds).	tmpzr1t_l9r_go_relaxed.owl	alginate biosynthetic process|alginic acid anabolism|alginate biosynthesis|alginic acid biosynthesis|alginic acid formation|alginic acid synthesis													biological_process											owl:Class	
GO:0044759	biolink:NamedThing	negative regulation by symbiont of host synaptic transmission	Any process in which a symbiont organism decreases the frequency, rate or extent of synaptic transmission, communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse, in its host organism.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-12-06T15:37:25Z					biological_process											owl:Class	
GO:1905309	biolink:NamedThing	positive regulation of cohesin loading	Any process that activates or increases the frequency, rate or extent of cohesin loading.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of cohesin localization to chromatin|positive regulation of cohesin association with chromatin							vw	2016-07-08T16:12:18Z					biological_process											owl:Class	
GO:0051983	biolink:NamedThing	regulation of chromosome segregation	Any process that modulates the frequency, rate or extent of chromosome segregation, the process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0043600	biolink:NamedThing	cytoplasmic replisome	A multi-component enzymatic machine at the cytoplasmic replication fork, which mediates DNA replication. Includes DNA primase, DNA polymerase, DNA helicase, and other proteins.	tmpzr1t_l9r_go_relaxed.owl	prokaryotic replisome													cellular_component											owl:Class	
GO:0002850	biolink:NamedThing	negative regulation of peripheral T cell tolerance induction	Any process that stops, prevents, or reduces the frequency, rate, or extent of peripheral T cell tolerance induction.	tmpzr1t_l9r_go_relaxed.owl	inhibition of peripheral T cell tolerance induction|down-regulation of peripheral T cell tolerance induction|downregulation of peripheral T cell tolerance induction|down regulation of peripheral T cell tolerance induction													biological_process											owl:Class	
GO:0002665	biolink:NamedThing	negative regulation of T cell tolerance induction	Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell tolerance induction.	tmpzr1t_l9r_go_relaxed.owl	down regulation of T cell tolerance induction|negative regulation of T-lymphocyte tolerance induction|inhibition of T cell tolerance induction|negative regulation of T-cell tolerance induction|negative regulation of T lymphocyte tolerance induction|downregulation of T cell tolerance induction|down-regulation of T cell tolerance induction													biological_process											owl:Class	
GO:1902781	biolink:NamedThing	cellular response to nonane	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nonane stimulus.	tmpzr1t_l9r_go_relaxed.owl								tt	2014-03-21T03:25:32Z					biological_process											owl:Class	
GO:1902779	biolink:NamedThing	cellular response to alkane	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alkane stimulus.	tmpzr1t_l9r_go_relaxed.owl								tt	2014-03-21T03:18:04Z					biological_process											owl:Class	
GO:0010029	biolink:NamedThing	regulation of seed germination	Any process that modulates the frequency, rate or extent of seed germination.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0050448	biolink:NamedThing	beta-cyclopiazonate dehydrogenase activity	Catalysis of the reaction: beta-cyclopiazonate + A = alpha-cyclopiazonate + AH(2).	tmpzr1t_l9r_go_relaxed.owl	b-cyclopiazonate dehydrogenase activity|beta-cyclopiazonate oxidocyclase activity|beta-cyclopiazonate:(acceptor) oxidoreductase (cyclizing)|beta-cyclopiazonate:acceptor oxidoreductase (cyclizing)|beta-cyclopiazonic oxidocyclase activity				MetaCyc:BETA-CYCLOPIAZONATE-DEHYDROGENASE-RXN|KEGG_REACTION:R04080|RHEA:14525|EC:1.21.99.1									molecular_function											owl:Class	
GO:1904555	biolink:NamedThing	L-proline transmembrane transport	The directed movement of L-proline across a membrane.	tmpzr1t_l9r_go_relaxed.owl								pr	2015-08-14T14:21:06Z					biological_process											owl:Class	
GO:0042546	biolink:NamedThing	cell wall biogenesis	A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cell wall. Includes biosynthesis of constituent macromolecules, such as proteins and polysaccharides, and those macromolecular modifications that are involved in synthesis or assembly of the cellular component. A cell wall is the rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells, maintaining their shape and protecting them from osmotic lysis.	tmpzr1t_l9r_go_relaxed.owl	cell wall assembly													biological_process											owl:Class	
GO:0047746	biolink:NamedThing	chlorophyllase activity	Catalysis of the reaction: chlorophyll + H2O = phytol + chlorophyllide.	tmpzr1t_l9r_go_relaxed.owl	chlorophyll chlorophyllidohydrolase activity				EC:3.1.1.14|MetaCyc:CHLOROPHYLLASE-RXN									molecular_function											owl:Class	
GO:0033573	biolink:NamedThing	high-affinity iron permease complex	A protein complex composed of a multicopper ferroxidase that oxidizes Fe(II) to Fe(III), and a ferric iron permease that transports the produced Fe(III) into the cell. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.	tmpzr1t_l9r_go_relaxed.owl	high affinity iron permease complex													cellular_component											owl:Class	
GO:0018844	biolink:NamedThing	2-hydroxytetrahydrofuran isomerase activity	Catalysis of the reaction: 2-hydroxytetrahydrofuran = 4-hydroxybutyraldehyde.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0019|EC:5.3.99.-									molecular_function											owl:Class	
GO:0051734	biolink:NamedThing	polynucleotide kinase activity	Catalysis of the reaction: ATP + 5'-dephosphopolynucleotide = ADP + 5'-phosphopolynucleotide. The polynucleotide may be DNA or RNA.	tmpzr1t_l9r_go_relaxed.owl	ATP-dependent polynucleotide kinase activity|ATP-dependent polynucleotide 5'-hydroxyl-kinase activity|ATP:5'-dephosphopolynucleotide 5'-phosphotransferase activity|ATP:5'-dephosphopolynucleotide 5'-phosphatase activity	https://github.com/geneontology/go-ontology/issues/21619			EC:2.7.1.78|RHEA:54580									molecular_function											owl:Class	
GO:1900607	biolink:NamedThing	tensidol B catabolic process	The chemical reactions and pathways resulting in the breakdown of tensidol B.	tmpzr1t_l9r_go_relaxed.owl	tensidol B breakdown|tensidol B degradation|tensidol B catabolism							di	2012-05-15T06:58:43Z					biological_process											owl:Class	
GO:0042722	biolink:NamedThing	alpha-beta T cell activation by superantigen	The change in morphology and behavior of alpha-beta T cells resulting from exposure to a superantigen, a microbial antigen with an extremely potent activating effect on T cells that bear a specific variable region.	tmpzr1t_l9r_go_relaxed.owl	alpha-beta T lymphocyte activation by superantigen|alpha-beta T-lymphocyte activation by superantigen|alpha-beta T-cell activation by superantigen													biological_process											owl:Class	
GO:0046631	biolink:NamedThing	alpha-beta T cell activation	The change in morphology and behavior of an alpha-beta T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.	tmpzr1t_l9r_go_relaxed.owl	alpha-beta T-cell activation|alpha-beta T-lymphocyte activation|alpha-beta T lymphocyte activation													biological_process											owl:Class	
GO:0005713	biolink:NamedThing	recombination nodule	An electron dense structure that is associated with meiotic chromosomes.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0016339	biolink:NamedThing	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules	The attachment of one cell to another cell via adhesion molecules that require the presence of calcium for the interaction.	tmpzr1t_l9r_go_relaxed.owl	calcium-dependent cell adhesion molecule activity													biological_process											owl:Class	
GO:0097641	biolink:NamedThing	alpha-ketoglutarate-dependent xanthine dioxygenase activity	Catalysis of the reaction: 2-oxoglutarate (alpha-ketoglutarate) + O2 + xanthine = CO2 + succinate + urate.	tmpzr1t_l9r_go_relaxed.owl	alpha-ketoglutarate- and Fe(II)-dependent xanthine hydroxylase activity|2-oxoglutarate-dependent xanthine dioxygenase activity|alpha-ketoglutarate- and Fe(II)-dependent xanthine dioxygenase activity				RHEA:43120			pr	2014-09-03T14:55:42Z					molecular_function											owl:Class	
GO:0071309	biolink:NamedThing	cellular response to phylloquinone	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a phylloquinone (vitamin K1) stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to vitamin K1							mah	2009-12-10T04:37:18Z					biological_process											owl:Class	
GO:0032573	biolink:NamedThing	response to phylloquinone	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a phylloquinone (vitamin K1) stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to vitamin K1													biological_process											owl:Class	
GO:0106089	biolink:NamedThing	negative regulation of cell adhesion involved in sprouting angiogenesis	Any process that stops, prevents or reduces the frequency, rate or extent of cell adhesion involved in sprouting angiogenesis.	tmpzr1t_l9r_go_relaxed.owl								hjd	2018-01-22T18:28:08Z					biological_process											owl:Class	
GO:0008776	biolink:NamedThing	acetate kinase activity	Catalysis of the reaction: ATP + acetate = ADP + acetyl phosphate.	tmpzr1t_l9r_go_relaxed.owl	acetokinase activity|AK activity|acetate kinase (phosphorylating) activity|ATP:acetate phosphotransferase activity|acetic kinase activity|AckA				EC:2.7.2.1|MetaCyc:ACETATEKIN-RXN|RHEA:11352									molecular_function											owl:Class	
GO:0046267	biolink:NamedThing	triethanolamine catabolic process	The chemical reactions and pathways resulting in the breakdown of triethanolamine, a combustible, hygroscopic, colorless liquid commonly used in dry-cleaning solutions, cosmetics, detergents, textile processing, wool scouring, and as a corrosion inhibitor and pharmaceutical alkalizing agent.	tmpzr1t_l9r_go_relaxed.owl	triethanolamine catabolism|triethanolamine breakdown|triethanolamine degradation													biological_process											owl:Class	
GO:0035293	biolink:NamedThing	chitin-based larval cuticle pattern formation	The process that gives rise to the patterns of cell differentiation in the chitin-based larval cuticle. An example of this is found in Drosophila melanogaster.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0099506	biolink:NamedThing	synaptic vesicle transport along actin filament	The directed movement of synaptic vesicles along actin filaments within a cell, powered by molecular motors.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0030050	biolink:NamedThing	vesicle transport along actin filament	Movement of a vesicle along an actin filament, mediated by motor proteins.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0008622	biolink:NamedThing	epsilon DNA polymerase complex	A heterotetrameric DNA polymerase complex that catalyzes processive DNA synthesis in the absence of PCNA, but is further stimulated in the presence of PCNA. The complex contains a large catalytic subunit and three small subunits, and is best characterized in Saccharomyces, in which the subunits are named Pol2p, Dpb2p, Dpb3p, and Dpb4p. Some evidence suggests that DNA polymerase epsilon is the leading strand polymerase; it is also involved in nucleotide-excision repair and mismatch repair.	tmpzr1t_l9r_go_relaxed.owl	DNA polymerase epsilon complex													cellular_component											owl:Class	
GO:0031429	biolink:NamedThing	box H/ACA snoRNP complex	A box H/ACA RNP complex that is located in the nucleolus.	tmpzr1t_l9r_go_relaxed.owl	box H/ACA small nucleolar ribonucleoprotein complex|box H/ACA snoRNP pseudouridylase complex													cellular_component											owl:Class	
GO:1904597	biolink:NamedThing	negative regulation of connective tissue replacement involved in inflammatory response wound healing	Any process that stops, prevents or reduces the frequency, rate or extent of connective tissue replacement involved in inflammatory response wound healing.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of connective tissue replacement involved in inflammatory response wound healing|inhibition of fibrosis during inflammatory response|downregulation of connective tissue replacement during inflammatory response|negative regulation of connective tissue replacement during inflammatory response|down regulation of connective tissue replacement during inflammatory response|negative regulation of fibrosis during inflammatory response|down-regulation of connective tissue replacement during inflammatory response|down regulation of fibrosis during inflammatory response|down regulation of connective tissue replacement involved in inflammatory response wound healing|downregulation of fibrosis during inflammatory response|downregulation of connective tissue replacement involved in inflammatory response wound healing|down-regulation of fibrosis during inflammatory response|inhibition of connective tissue replacement involved in inflammatory response wound healing|inhibition of connective tissue replacement during inflammatory response							krc	2015-08-25T20:52:30Z					biological_process											owl:Class	
GO:1904596	biolink:NamedThing	regulation of connective tissue replacement involved in inflammatory response wound healing	Any process that modulates the frequency, rate or extent of connective tissue replacement involved in inflammatory response wound healing.	tmpzr1t_l9r_go_relaxed.owl	regulation of fibrosis during inflammatory response|regulation of connective tissue replacement during inflammatory response							krc	2015-08-25T20:52:24Z					biological_process											owl:Class	
GO:0032272	biolink:NamedThing	negative regulation of protein polymerization	Any process that stops, prevents, or reduces the frequency, rate or extent of the process of creating protein polymers.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of protein polymerization|inhibition of protein polymerization|down regulation of protein polymerization|downregulation of protein polymerization													biological_process											owl:Class	
GO:0060259	biolink:NamedThing	regulation of feeding behavior	Any process that modulates the rate, frequency or extent of the behavior associated with the intake of food.	tmpzr1t_l9r_go_relaxed.owl	regulation of feeding behaviour													biological_process											owl:Class	
GO:0010257	biolink:NamedThing	NADH dehydrogenase complex assembly	The aggregation, arrangement and bonding together of a set of components to form an NADH dehydrogenase complex.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0090188	biolink:NamedThing	negative regulation of pancreatic juice secretion	Any process that decreases the rate, frequency or extent of pancreatic juice secretion, the regulated release of pancreatic juice by the exocrine pancreas into the upper part of the intestine.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-12-18T11:03:24Z					biological_process											owl:Class	
GO:0001831	biolink:NamedThing	trophectodermal cellular morphogenesis	The morphogenesis of trophectoderm cells.	tmpzr1t_l9r_go_relaxed.owl	trophectoderm cellular morphogenesis					See also the Anatomical Dictionary for Mouse Development ontology terms 'TS4, trophectoderm ; EMAP:19', 'TS5, trophectoderm ; EMAP:28' and 'TS6, trophectoderm ; EMAP:39'.								biological_process											owl:Class	
GO:0046247	biolink:NamedThing	terpene catabolic process	The chemical reactions and pathways resulting in the breakdown of terpenes, any of a large group of hydrocarbons made up of isoprene units.	tmpzr1t_l9r_go_relaxed.owl	terpene breakdown|terpene catabolism|terpene degradation													biological_process											owl:Class	
GO:0089701	biolink:NamedThing	U2AF complex	A heterodimeric protein complex consisting of conserved large and small U2AF subunits that contributes to spliceosomal RNA splicing by binding to consensus sequences at the 3' splice site. U2AF is required to stabilize the association of the U2 snRNP with the branch point.	tmpzr1t_l9r_go_relaxed.owl	U2 accessory factor|U2AF													cellular_component											owl:Class	
GO:0002279	biolink:NamedThing	mast cell activation involved in immune response	The change in morphology and behavior of a mast cell resulting from exposure to a cytokine, chemokine, soluble factor, or to (at least in mammals) an antigen which the mast cell has specifically bound via IgE bound to Fc-epsilonRI receptors, leading to the initiation or perpetuation of an immune response.	tmpzr1t_l9r_go_relaxed.owl	mast cell activation during immune response													biological_process											owl:Class	
GO:0045576	biolink:NamedThing	mast cell activation	The change in morphology and behavior of a mast cell resulting from exposure to a cytokine, chemokine, soluble factor, or to (at least in mammals) an antigen which the mast cell has specifically bound via IgE bound to Fc-epsilonRI receptors.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0033066	biolink:NamedThing	Rad51B-Rad51C complex	A DNA recombinase mediator complex that contains the Rad51 paralogs RAD51B and RAD51C, or orthologs thereof.	tmpzr1t_l9r_go_relaxed.owl	BC complex													cellular_component											owl:Class	
GO:0090100	biolink:NamedThing	positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway	Any process that increases the rate, frequency, or extent of the series of molecular signals generated as a consequence of a transmembrane receptor serine/threonine kinase binding to its physiological ligand.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of transmembrane receptor protein serine/threonine kinase signalling pathway							tb	2009-11-13T10:55:53Z					biological_process											owl:Class	
GO:0075245	biolink:NamedThing	positive regulation of oospore formation	Any process that activates, maintains or increases the frequency, rate or extent of oospore formation, a process in which male and female gametangia develop and fuse to form a thick-walled resting spore of oomycetes.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0043941	biolink:NamedThing	positive regulation of sexual sporulation resulting in formation of a cellular spore	Any process that activates, maintains or increases the frequency, rate or extent of the formation of cellular spores derived from the products of meiosis.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0006795	biolink:NamedThing	regulation of phosphorus utilization	Any process that modulates the frequency, rate or extent of phosphorus utilization.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0080139	biolink:NamedThing	borate efflux transmembrane transporter activity	Enables the transfer of borate from the inside of the cell to the outside of the cell across a membrane.	tmpzr1t_l9r_go_relaxed.owl	boron efflux transmembrane transporter activity							dhl	2009-05-19T04:11:45Z					molecular_function											owl:Class	
GO:1902367	biolink:NamedThing	negative regulation of Notch signaling pathway involved in somitogenesis	Any process that stops, prevents or reduces the frequency, rate or extent of Notch signaling pathway involved in somitogenesis.	tmpzr1t_l9r_go_relaxed.owl	down regulation of N signalling pathway involved in somitogenesis|negative regulation of N signalling pathway involved in somitogenesis|downregulation of N signaling pathway involved in somitogenesis|downregulation of Notch receptor signaling pathway involved in formation of mesodermal clusters|downregulation of Notch-receptor signaling pathway involved in somitogenesis|negative regulation of Notch receptor signalling pathway involved in somitogenesis|downregulation of Notch-receptor signalling pathway involved in formation of mesodermal clusters|inhibition of Notch-receptor signalling pathway involved in somitogenesis|negative regulation of Notch signalling pathway involved in somitogenesis|down regulation of Notch-receptor signalling pathway involved in somitogenesis|down regulation of N signaling pathway involved in formation of mesodermal clusters|inhibition of Notch signalling pathway involved in somitogenesis|inhibition of Notch signaling pathway involved in formation of mesodermal clusters|down-regulation of Notch-receptor signalling pathway involved in somitogenesis|negative regulation of N signalling pathway involved in formation of mesodermal clusters|downregulation of Notch signalling pathway involved in formation of mesodermal clusters|down regulation of Notch receptor signaling pathway involved in formation of mesodermal clusters|down regulation of Notch receptor signaling pathway involved in somitogenesis|down-regulation of Notch receptor signaling pathway involved in formation of mesodermal clusters|down-regulation of Notch receptor signaling pathway involved in somitogenesis|inhibition of Notch signaling pathway involved in somitogenesis|downregulation of Notch signaling pathway involved in formation of mesodermal clusters|down-regulation of Notch-receptor signalling pathway involved in formation of mesodermal clusters|down regulation of Notch signalling pathway involved in somitogenesis|negative regulation of Notch-receptor signaling pathway involved in formation of mesodermal clusters|down regulation of Notch receptor signalling pathway involved in somitogenesis|negative regulation of Notch receptor signaling pathway involved in formation of mesodermal clusters|negative regulation of Notch signalling pathway involved in formation of mesodermal clusters|down regulation of Notch signaling pathway involved in formation of mesodermal clusters|down-regulation of Notch receptor signalling pathway involved in formation of mesodermal clusters|down-regulation of Notch signaling pathway involved in formation of mesodermal clusters|down-regulation of Notch receptor signalling pathway involved in somitogenesis|downregulation of Notch signalling pathway involved in somitogenesis|negative regulation of Notch-receptor signalling pathway involved in formation of mesodermal clusters|negative regulation of Notch receptor signaling pathway involved in somitogenesis|downregulation of Notch receptor signaling pathway involved in somitogenesis|down regulation of Notch receptor signalling pathway involved in formation of mesodermal clusters|down-regulation of Notch signalling pathway involved in somitogenesis|negative regulation of Notch-receptor signaling pathway involved in somitogenesis|inhibition of Notch receptor signalling pathway involved in formation of mesodermal clusters|down-regulation of N signaling pathway involved in somitogenesis|down regulation of N signaling pathway involved in somitogenesis|down-regulation of Notch signaling pathway involved in somitogenesis|inhibition of Notch-receptor signalling pathway involved in formation of mesodermal clusters|downregulation of N signalling pathway involved in somitogenesis|inhibition of Notch receptor signaling pathway involved in somitogenesis|inhibition of N signalling pathway involved in formation of mesodermal clusters|down-regulation of Notch-receptor signaling pathway involved in somitogenesis|inhibition of Notch receptor signaling pathway involved in formation of mesodermal clusters|negative regulation of N signaling pathway involved in somitogenesis|inhibition of Notch signalling pathway involved in formation of mesodermal clusters|downregulation of Notch receptor signalling pathway involved in somitogenesis|inhibition of Notch-receptor signaling pathway involved in formation of mesodermal clusters|negative regulation of Notch receptor signalling pathway involved in formation of mesodermal clusters|downregulation of Notch signaling pathway involved in somitogenesis|inhibition of N signalling pathway involved in somitogenesis|down regulation of Notch signaling pathway involved in somitogenesis|negative regulation of Notch signaling pathway involved in formation of mesodermal clusters|negative regulation of N signaling pathway involved in formation of mesodermal clusters|down regulation of Notch-receptor signaling pathway involved in formation of mesodermal clusters|inhibition of Notch receptor signalling pathway involved in somitogenesis|downregulation of Notch receptor signalling pathway involved in formation of mesodermal clusters|down-regulation of N signalling pathway involved in formation of mesodermal clusters|down regulation of Notch-receptor signaling pathway involved in somitogenesis|down-regulation of Notch signalling pathway involved in formation of mesodermal clusters|down regulation of N signalling pathway involved in formation of mesodermal clusters|downregulation of Notch-receptor signaling pathway involved in formation of mesodermal clusters|down-regulation of Notch-receptor signaling pathway involved in formation of mesodermal clusters|inhibition of Notch-receptor signaling pathway involved in somitogenesis|downregulation of N signalling pathway involved in formation of mesodermal clusters|inhibition of N signaling pathway involved in formation of mesodermal clusters|down regulation of Notch signalling pathway involved in formation of mesodermal clusters|down-regulation of N signalling pathway involved in somitogenesis|down regulation of Notch-receptor signalling pathway involved in formation of mesodermal clusters|inhibition of N signaling pathway involved in somitogenesis|downregulation of N signaling pathway involved in formation of mesodermal clusters|down-regulation of N signaling pathway involved in formation of mesodermal clusters|negative regulation of Notch-receptor signalling pathway involved in somitogenesis|downregulation of Notch-receptor signalling pathway involved in somitogenesis							dph	2013-08-20T18:27:20Z					biological_process											owl:Class	
GO:1902366	biolink:NamedThing	regulation of Notch signaling pathway involved in somitogenesis	Any process that modulates the frequency, rate or extent of Notch signaling pathway involved in somitogenesis.	tmpzr1t_l9r_go_relaxed.owl	regulation of N signalling pathway involved in somitogenesis|regulation of Notch receptor signaling pathway involved in somitogenesis|regulation of N signaling pathway involved in formation of mesodermal clusters|regulation of Notch-receptor signaling pathway involved in somitogenesis|regulation of Notch-receptor signalling pathway involved in formation of mesodermal clusters|regulation of Notch receptor signalling pathway involved in formation of mesodermal clusters|regulation of N signalling pathway involved in formation of mesodermal clusters|regulation of Notch-receptor signaling pathway involved in formation of mesodermal clusters|regulation of Notch receptor signalling pathway involved in somitogenesis|regulation of N signaling pathway involved in somitogenesis|regulation of Notch-receptor signalling pathway involved in somitogenesis|regulation of Notch receptor signaling pathway involved in formation of mesodermal clusters|regulation of Notch signalling pathway involved in somitogenesis|regulation of Notch signaling pathway involved in formation of mesodermal clusters|regulation of Notch signalling pathway involved in formation of mesodermal clusters							dph	2013-08-20T18:24:23Z					biological_process											owl:Class	
GO:0140568	biolink:NamedThing	extraction of mislocalized protein from membrane	The removal of a mislocalized protein from a cellular membrane.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/20237						pg	2020-12-15T07:35:10Z					biological_process											owl:Class	
GO:0033070	biolink:NamedThing	ansamycin biosynthetic process	The chemical reactions and pathways leading to the formation of ansamycins, any of a group of complex macrolactam compounds characterized by a cyclic structure in which an aliphatic ansa chain forms a bridge between two non-adjacent positions of a cyclic p-system; many exhibit antibacterial, antifungal or antitumor activity.	tmpzr1t_l9r_go_relaxed.owl	ansamycin biosynthesis|ansamycin formation|ansamycin synthesis|ansamycin anabolism													biological_process											owl:Class	
GO:0046226	biolink:NamedThing	coumarin catabolic process	The chemical reactions and pathways resulting in the breakdown of coumarins, compounds derived from the phenylacrylic skeleton of cinnamic acids.	tmpzr1t_l9r_go_relaxed.owl	coumarin degradation|coumarin catabolism|coumarin breakdown													biological_process											owl:Class	
GO:0046271	biolink:NamedThing	phenylpropanoid catabolic process	The chemical reactions and pathways resulting in the breakdown of aromatic derivatives of trans-cinnamic acid.	tmpzr1t_l9r_go_relaxed.owl	phenylpropanoid catabolism|phenylpropanoid degradation|phenylpropanoid breakdown													biological_process											owl:Class	
GO:0070185	biolink:NamedThing	mitochondrial valyl-tRNA aminoacylation	The process of coupling valine to valyl-tRNA in a mitochondrion, catalyzed by valyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0102949	biolink:NamedThing	1,2-rhamnosyltransferase activity	Catalysis of the reaction: isoorientin + an L-rhamonsylated rhamnosyl acceptor = isoorientin 2'-O-rhamnoside + a non rhamnosylated rhamnosyl acceptor.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-9082									molecular_function											owl:Class	
GO:0061944	biolink:NamedThing	negative regulation of protein K48-linked ubiquitination	Any process that stops, prevents or reduces the frequency, rate or extent of K48-linked ubiquitination, a protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 48 of the ubiquitin monomers, is added to a protein. K48-linked ubiquitination targets the substrate protein for degradation.	tmpzr1t_l9r_go_relaxed.owl								dph	2017-09-22T11:37:18Z					biological_process											owl:Class	
GO:1902915	biolink:NamedThing	negative regulation of protein polyubiquitination	Any process that stops, prevents or reduces the frequency, rate or extent of protein polyubiquitination.	tmpzr1t_l9r_go_relaxed.owl	down regulation of protein polyubiquitylation|down regulation of protein polyubiquitinylation|negative regulation of protein polyubiquitylation|downregulation of protein polyubiquitination|downregulation of protein polyubiquitylation|inhibition of protein polyubiquitylation|down-regulation of protein polyubiquitylation|down regulation of protein polyubiquitination|downregulation of polyubiquitin|down-regulation of protein polyubiquitination|inhibition of polyubiquitin|negative regulation of protein polyubiquitinylation|negative regulation of polyubiquitin|down regulation of polyubiquitin|down-regulation of polyubiquitin|down-regulation of protein polyubiquitinylation|inhibition of protein polyubiquitinylation|inhibition of protein polyubiquitination|downregulation of protein polyubiquitinylation							di	2014-04-18T22:09:58Z					biological_process											owl:Class	
GO:0043474	biolink:NamedThing	pigment metabolic process involved in pigmentation	The chemical reactions and pathways involving a pigment, any general or particular coloring matter in living organisms, resulting in the deposition or aggregation of pigment in an organism, tissue or cell.	tmpzr1t_l9r_go_relaxed.owl	pigment metabolism during pigmentation|pigment metabolic process during pigmentation													biological_process											owl:Class	
GO:0098750	biolink:NamedThing	FYXD domain binding	Binding to a FXYD domain.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0015267	biolink:NamedThing	channel activity	Enables the energy-independent facilitated diffusion, mediated by passage of a solute through a transmembrane aqueous pore or channel. Stereospecificity is not exhibited but this transport may be specific for a particular molecular species or class of molecules.	tmpzr1t_l9r_go_relaxed.owl	pore class transporter activity|substrate-specific channel activity|nonselective channel activity|channel-forming toxin activity|pore activity|alpha-type channel activity|channel/pore class transporter activity				Reactome:R-HSA-3779381|Reactome:R-HSA-8953430|TC:1							GO:0022838|GO:0015249|GO:0015268		molecular_function											owl:Class	
GO:0018564	biolink:NamedThing	carbazole 1,9a-dioxygenase activity	Catalysis of the reaction: carbazole + NADH + O2 + H+ = NAD+ + 2'-aminobiphenyl-2,3-diol.	tmpzr1t_l9r_go_relaxed.owl	carbazole 1,9alpha-dioxygenase activity				UM-BBD_reactionID:r0456|EC:1.13.11.-									molecular_function											owl:Class	
GO:0008377	biolink:NamedThing	light-induced release of internally sequestered calcium ion	The process in which the detection of light triggers the release of internally sequestered calcium ions.	tmpzr1t_l9r_go_relaxed.owl	light-induced release of calcium from internal store|light-induced release of internally stored calcium ion (Ca2+)|light-induced release of internally sequestered calcium ion (Ca2+)													biological_process											owl:Class	
GO:0043103	biolink:NamedThing	hypoxanthine salvage	Any process that generates hypoxanthine, 6-hydroxy purine, from derivatives of it without de novo synthesis.	tmpzr1t_l9r_go_relaxed.owl	adenine, hypoxanthine and their nucleoside salvage|guanine, xanthine and their nucleoside salvage													biological_process											owl:Class	
GO:0002900	biolink:NamedThing	positive regulation of central B cell deletion	Any process that activates or increases the frequency, rate, or extent of central B cell deletion.	tmpzr1t_l9r_go_relaxed.owl	up regulation of central B cell deletion|up-regulation of central B cell deletion|stimulation of central B cell deletion|upregulation of central B cell deletion|activation of central B cell deletion													biological_process											owl:Class	
GO:0021526	biolink:NamedThing	medial motor column neuron differentiation	The process in which differentiating motor neurons in the neural tube acquire the specialized structural and/or functional features of medial motor column neurons. Medial motor column neurons are generated at all rostrocaudal levels and send axons to the axial muscles (medial group) and to the body wall muscles (lateral group). Differentiation includes the processes involved in commitment of a cell to a specific fate.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0021515	biolink:NamedThing	cell differentiation in spinal cord	The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the spinal cord. Differentiation includes the processes involved in commitment of a cell to a specific fate.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0048140	biolink:NamedThing	male germ-line cyst encapsulation	Formation of a single follicular epithelium around the germ-line derived cells of a cyst formed in the male gonad.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0034556	biolink:NamedThing	nitrobenzoate nitroreductase activity	Catalysis of the reaction: o-nitrobenzoate + NADPH + H+ = o-hydroxylaminobenzoate + NADP+.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0849|EC:1.7.1.-									molecular_function											owl:Class	
GO:0106316	biolink:NamedThing	nitrite reductase NADH activity	Catalysis of the reaction: ammonium hydroxide + 3 NAD+ + H2O = nitrite + 3 NADH + 3 H+.	tmpzr1t_l9r_go_relaxed.owl					RHEA:24628			hjd	2020-09-23T14:34:02Z					molecular_function											owl:Class	
GO:0008942	biolink:NamedThing	nitrite reductase [NAD(P)H] activity	Catalysis of the reaction: ammonium hydroxide + 3 NAD(P)+ + H2O = nitrite + 3 NAD(P)H + 3 H+.	tmpzr1t_l9r_go_relaxed.owl	NAD(P)H2:nitrite oxidoreductase activity|ammonium-hydroxide:NAD(P)+ oxidoreductase activity|nitrite reductase (reduced nicotinamide adenine dinucleotide (phosphate)) activity|NADH-nitrite oxidoreductase activity|assimilatory nitrite reductase activity|nitrite reductase [NAD(P)H2]|NADPH-nitrite reductase activity|NAD(P)H:nitrite oxidoreductase activity				KEGG_REACTION:R00789|MetaCyc:NITRITREDUCT-RXN|KEGG_REACTION:R00787|EC:1.7.1.4	Note that this function was formerly EC:1.6.6.4.								molecular_function											owl:Class	
GO:2000152	biolink:NamedThing	regulation of ubiquitin-specific protease activity	Any process that modulates the frequency, rate or extent of regulation of ubiquitin-specific protease activity (deubiquitinase) activity.	tmpzr1t_l9r_go_relaxed.owl	regulation of UCH2|regulation of deubiquitinase activity|regulation of UBP							tb	2010-10-01T10:09:28Z					biological_process											owl:Class	
GO:0060369	biolink:NamedThing	positive regulation of Fc receptor mediated stimulatory signaling pathway	Any process that increases the rate, frequency or extent of the Fc receptor mediated stimulatory signaling pathway. The Fc receptor mediated stimulatory signaling pathway is a series of molecular signals generated as a consequence of a the binding of the Fc portion of an immunoglobulin by an Fc receptor capable of activating or perpetuating an immune response. The Fc portion of an immunoglobulin is its C-terminal constant region.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of Fc receptor mediated stimulatory signalling pathway													biological_process											owl:Class	
GO:0060163	biolink:NamedThing	subpallium neuron fate commitment	The process in which in the subpallium, the developmental fate of a cell becomes restricted such that it will develop into a neuron. The subpallium is the base region of the telencephalon.	tmpzr1t_l9r_go_relaxed.owl	subpallium neuronal precursor fate commitment													biological_process											owl:Class	
GO:0000353	biolink:NamedThing	formation of quadruple SL/U4/U5/U6 snRNP	Formation of a quadruple snRNP complex composed of the spliced leader (SL) RNA along with the U4/U6-U5 tri-snRNP complex. Interactions that may facilitate this include a duplex between the SL and U6 RNAs and interactions between the U5 RNA and the exon sequence at the 5' splice site within the SL RNA.	tmpzr1t_l9r_go_relaxed.owl						Note that this step is analogous to 5' splice site selection in cis-splicing.								biological_process											owl:Class	
GO:0033306	biolink:NamedThing	phytol metabolic process	The chemical reactions and pathways involving phytol, (2E,7R,11R)-3,7,11,15-tetramethylhexadec-2-en-1-ol.	tmpzr1t_l9r_go_relaxed.owl	phytol metabolism													biological_process											owl:Class	
GO:1903173	biolink:NamedThing	fatty alcohol metabolic process	The chemical reactions and pathways involving fatty alcohol.	tmpzr1t_l9r_go_relaxed.owl	fatty alcohol metabolism							tt	2014-07-14T01:51:41Z					biological_process											owl:Class	
GO:1902427	biolink:NamedThing	regulation of water channel activity	Any process that modulates the frequency, rate or extent of water channel activity.	tmpzr1t_l9r_go_relaxed.owl	regulation of aquaporin|regulation of aquaporin permeability							bf	2013-09-23T12:56:31Z					biological_process											owl:Class	
GO:0034587	biolink:NamedThing	piRNA metabolic process	The chemical reactions and pathways involving piRNAs, Piwi-associated RNAs, a class of 24- to 30-nucleotide RNA derived from repeat or complex DNA sequence elements and processed by a Dicer-independent mechanism.	tmpzr1t_l9r_go_relaxed.owl	piRNA metabolism|Piwi-associated RNA metabolic process													biological_process											owl:Class	
GO:1901229	biolink:NamedThing	regulation of non-canonical Wnt signaling pathway via JNK cascade	Any process that modulates the frequency, rate or extent of non-canonical Wnt signaling pathway via JNK cascade.	tmpzr1t_l9r_go_relaxed.owl	regulation of non-canonical Wnt receptor signaling pathway via JNK cascade|regulation of non-canonical Wnt-activated signaling pathway via JNK cascade|regulation of non-canonical Wnt receptor signalling pathway via JNK cascade							vk	2012-08-07T14:14:16Z					biological_process											owl:Class	
GO:0046040	biolink:NamedThing	IMP metabolic process	The chemical reactions and pathways involving IMP, inosine monophosphate.	tmpzr1t_l9r_go_relaxed.owl	IMP metabolism													biological_process											owl:Class	
GO:0006545	biolink:NamedThing	glycine biosynthetic process	The chemical reactions and pathways resulting in the formation of glycine, aminoethanoic acid.	tmpzr1t_l9r_go_relaxed.owl	glycine biosynthesis|glycine formation|glycine anabolism|glycine synthesis				MetaCyc:GLYCINE-SYN2-PWY									biological_process											owl:Class	
GO:0006544	biolink:NamedThing	glycine metabolic process	The chemical reactions and pathways involving glycine, aminoethanoic acid.	tmpzr1t_l9r_go_relaxed.owl	glycine metabolism													biological_process											owl:Class	
GO:1903724	biolink:NamedThing	positive regulation of centriole elongation	Any process that activates or increases the frequency, rate or extent of centriole elongation.	tmpzr1t_l9r_go_relaxed.owl	activation of centriole elongation|up regulation of centriole elongation|up-regulation of centriole elongation|upregulation of centriole elongation							als	2014-12-09T16:36:20Z					biological_process											owl:Class	
GO:1903722	biolink:NamedThing	regulation of centriole elongation	Any process that modulates the frequency, rate or extent of centriole elongation.	tmpzr1t_l9r_go_relaxed.owl								als	2014-12-09T16:36:02Z					biological_process											owl:Class	
GO:0031999	biolink:NamedThing	negative regulation of fatty acid beta-oxidation	Any process that stops, prevents, or reduces the frequency, rate or extent of fatty acid beta-oxidation.	tmpzr1t_l9r_go_relaxed.owl	down regulation of fatty acid beta-oxidation|inhibition of fatty acid beta-oxidation|downregulation of fatty acid beta-oxidation|down-regulation of fatty acid beta-oxidation													biological_process											owl:Class	
GO:1904477	biolink:NamedThing	positive regulation of small GTPase binding	Any process that activates or increases the frequency, rate or extent of small GTPase binding.	tmpzr1t_l9r_go_relaxed.owl	up regulation of small GTPase binding|up-regulation of small GTPase binding|upregulation of small GTPase binding|positive regulation of Ras GTPase binding|activation of Ras GTPase binding	https://github.com/geneontology/go-ontology/issues/18750						sl	2015-07-10T22:47:43Z					biological_process											owl:Class	
GO:0042194	biolink:NamedThing	quinate biosynthetic process	The chemical reactions and pathways resulting in the formation of quinate, the anion of quinic acid.	tmpzr1t_l9r_go_relaxed.owl	quinic acid biosynthetic process|quinic acid biosynthesis|quinate biosynthesis|quinate synthesis|quinate formation|quinate anabolism													biological_process											owl:Class	
GO:0001861	biolink:NamedThing	complement component C4b receptor activity	Combining with the C4b product of the classical complement cascade and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0016019	biolink:NamedThing	peptidoglycan immune receptor activity	Combining with a peptidoglycan and transmitting the signal to initiate an innate immune response.	tmpzr1t_l9r_go_relaxed.owl	peptidoglycan recognition activity|peptidoglycan receptor activity					Note that only peptidoglycan recognition proteins with receptor activity should be annotated to this term; otherwise use 'peptidoglycan binding ; GO:0042834' instead.								molecular_function											owl:Class	
GO:0120158	biolink:NamedThing	positive regulation of collagen catabolic process	Any process that activates or increases the frequency, rate or extent of collagen catabolism. Collagen catabolism is the proteolytic chemical reactions and pathways resulting in the breakdown of collagen in the extracellular matrix.	tmpzr1t_l9r_go_relaxed.owl	up regulation of collagen catabolic process|positive regulation of collagen degradation|upregulation of collagen catabolic process|positive regulation of collagen catabolism|positive regulation of collagen breakdown|activation of collagen catabolic process|up-regulation of collagen catabolic process							krc	2018-05-11T16:31:42Z					biological_process											owl:Class	
GO:1902618	biolink:NamedThing	cellular response to fluoride	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fluoride stimulus.	tmpzr1t_l9r_go_relaxed.owl								kmv	2014-01-10T19:41:58Z					biological_process											owl:Class	
GO:0005031	biolink:NamedThing	tumor necrosis factor-activated receptor activity	Combining with tumor necrosis factor, a proinflammatory cytokine produced by monocytes and macrophages, to initiate a change in cell function.	tmpzr1t_l9r_go_relaxed.owl	tumor necrosis factor receptor activity|TNF receptor activity, type II|tumor necrosis factor receptor activity, type II|TNF receptor activity|NGF/TNF (6 C-domain) receptor activity|tumor necrosis factor receptor activity, type I|TNF receptor activity, type I											GO:0005033|GO:0005032		molecular_function											owl:Class	
GO:1902115	biolink:NamedThing	regulation of organelle assembly	Any process that modulates the frequency, rate or extent of organelle assembly.	tmpzr1t_l9r_go_relaxed.owl								pr	2013-05-14T09:43:21Z					biological_process											owl:Class	
GO:0002728	biolink:NamedThing	negative regulation of natural killer cell cytokine production	Any process that stops, prevents, or reduces the frequency, rate, or extent of natural killer cell cytokine production.	tmpzr1t_l9r_go_relaxed.owl	down regulation of natural killer cell cytokine production|negative regulation of NK cell cytokine production|inhibition of natural killer cell cytokine production|downregulation of natural killer cell cytokine production|down-regulation of natural killer cell cytokine production													biological_process											owl:Class	
GO:0002727	biolink:NamedThing	regulation of natural killer cell cytokine production	Any process that modulates the frequency, rate, or extent of natural killer cell cytokine production.	tmpzr1t_l9r_go_relaxed.owl	regulation of NK cell cytokine production													biological_process											owl:Class	
GO:0061502	biolink:NamedThing	early endosome to recycling endosome transport	The directed movement of substances, in membrane-bounded vesicles, from the early sorting endosomes to the recycling endosomes.	tmpzr1t_l9r_go_relaxed.owl								dph	2013-01-04T07:24:56Z					biological_process											owl:Class	
GO:0098927	biolink:NamedThing	vesicle-mediated transport between endosomal compartments	A cellular transport process in which transported substances are moved in membrane-bounded vesicles between endosomal compartments, e.g, between early endosome and sorting endosome.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0016428	biolink:NamedThing	tRNA (cytosine-5-)-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing 5-methylcytosine.	tmpzr1t_l9r_go_relaxed.owl	S-adenosyl-L-methionine:tRNA (cytosine-5-)-methyltransferase activity|transfer RNA cytosine 5-methyltransferase activity|transfer ribonucleate cytosine 5-methyltransferase activity				Reactome:R-HSA-6782419|Reactome:R-HSA-6782388|Reactome:R-HSA-8932765|Reactome:R-HSA-6785409|Reactome:R-HSA-6785438									molecular_function											owl:Class	
GO:0034547	biolink:NamedThing	N-cyclopropylmelamine deaminase activity	Catalysis of the reaction: cyromazine + H2O = N-cyclopropylammeline + NH3.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-8018|UM-BBD_reactionID:r0825									molecular_function											owl:Class	
GO:0042066	biolink:NamedThing	perineurial glial growth	Glial cell growth that occurs in the perineurium, a cell layer that ensheaths projections of peripheral nerves, such as motor axons.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0042065	biolink:NamedThing	glial cell growth	Growth of glial cells, non-neuronal cells that provide support and nutrition, maintain homeostasis, form myelin, and participate in signal transmission in the nervous system.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0004555	biolink:NamedThing	alpha,alpha-trehalase activity	Catalysis of the reaction: alpha,alpha-trehalose + H2O = 2 D-glucose.	tmpzr1t_l9r_go_relaxed.owl	alpha,alpha-trehalose glucohydrolase activity				RHEA:32675|MetaCyc:TREHALA-RXN|EC:3.2.1.28|Reactome:R-HSA-188985									molecular_function											owl:Class	
GO:0015927	biolink:NamedThing	trehalase activity	Catalysis of the hydrolysis of trehalose or a trehalose derivative.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:TREHALA-RXN									molecular_function											owl:Class	
GO:0060392	biolink:NamedThing	negative regulation of SMAD protein signal transduction	Any process that decreases the rate, frequency or extent of the SMAD protein signaling pathway. Pathway-restricted SMAD proteins and common-partner SMAD proteins are involved in the transforming growth factor beta receptor signaling pathways.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of SMAD protein import into nucleus|negative regulation of SMAD protein nuclear translocation													biological_process											owl:Class	
GO:0034491	biolink:NamedThing	neutral amino acid transmembrane import into vacuole	The directed movement of neutral amino acids into the vacuole across the vacuolar membrane.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0050114	biolink:NamedThing	myo-inosose-2 dehydratase activity	Catalysis of the reaction: 2,4,6/3,5-pentahydroxycyclohexanone = 3D-3,5/4-trihydroxycyclohexane-1,2-dione + H(2)O.	tmpzr1t_l9r_go_relaxed.owl	2,4,6/3,5-pentahydroxycyclohexanone hydro-lyase activity|ketoinositol dehydratase activity|2,4,6/3,5-pentahydroxycyclohexanone hydro-lyase (3,5/4-trihydroxycyclohexa-1,2-dione-forming)|inosose 2,3-dehydratase activity				MetaCyc:MYO-INOSOSE-2-DEHYDRATASE-RXN|RHEA:14065|KEGG_REACTION:R02782|EC:4.2.1.44									molecular_function											owl:Class	
GO:0102378	biolink:NamedThing	steviolmonoside glucosyltransferase activity	Catalysis of the reaction: steviolmonoside + UDP-alpha-D-glucose = rubusoside + UDP + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-13512									molecular_function											owl:Class	
GO:0140082	biolink:NamedThing	SUMO-ubiquitin ligase activity	Isoenergetic transfer of SUMO from one protein to an existing ubiquitin chain via the reaction X-ubiquitin + Y-ubiquitin -> Y-ubiquitin-ubiquitin + X, where both the X-ubiquitin and Y-ubiquitin-ubiquitin linkages are thioester bonds between the C-terminal glycine of ubiquitin and a sulfhydryl side group of a cysteine residue.	tmpzr1t_l9r_go_relaxed.owl								pg	2017-08-08T14:46:50Z					molecular_function											owl:Class	
GO:0061665	biolink:NamedThing	SUMO ligase activity	Catalysis of the transfer of SUMO to a substrate protein via the reaction X-SUMO + S --> X + S-SUMO, where X is either an E2 or E3 enzyme, the X-SUMO linkage is a thioester bond, and the S-SUMO linkage is an isopeptide bond between the C-terminal amino acid of SUMO and the epsilon-amino group of lysine residues in the substrate.	tmpzr1t_l9r_go_relaxed.owl	E3							dph	2014-11-06T14:00:44Z					molecular_function											owl:Class	
GO:0002450	biolink:NamedThing	B cell antigen processing and presentation	The process in which a B cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex.	tmpzr1t_l9r_go_relaxed.owl	B-lymphocyte antigen processing and presentation|B lymphocyte antigen processing and presentation|B-cell antigen processing and presentation													biological_process											owl:Class	
GO:0009722	biolink:NamedThing	detection of cytokinin stimulus	The series of events in which a cytokinin stimulus is received by a cell and converted into a molecular signal.	tmpzr1t_l9r_go_relaxed.owl	perception of cytokinin stimulus													biological_process											owl:Class	
GO:0009720	biolink:NamedThing	detection of hormone stimulus	The series of events in which a hormone stimulus is received by a cell and converted into a molecular signal.	tmpzr1t_l9r_go_relaxed.owl	perception of hormone stimulus													biological_process											owl:Class	
GO:1902123	biolink:NamedThing	(-)-pinoresinol catabolic process	The chemical reactions and pathways resulting in the breakdown of (-)-pinoresinol.	tmpzr1t_l9r_go_relaxed.owl	(-)-pinoresinol degradation|(-)-pinoresinol catabolism|(-)-pinoresinol breakdown							ms	2013-05-21T08:49:05Z					biological_process											owl:Class	
GO:1904851	biolink:NamedThing	positive regulation of establishment of protein localization to telomere	Any process that activates or increases the frequency, rate or extent of establishment of protein localization to telomere.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of establishment of protein localization to chromosome, telomeric region|positive regulation of establishment of protein localisation to telomere|positive regulation of establishment of protein localization to chromosome, telomeric region|activation of establishment of protein localisation to telomere|activation of establishment of protein localization to chromosome, telomeric region|activation of establishment of protein localization to telomere|upregulation of establishment of protein localization to telomere|up-regulation of establishment of protein localization to telomere|upregulation of establishment of protein localisation to telomere|upregulation of establishment of protein localization to chromosome, telomeric region|up regulation of establishment of protein localization to chromosome, telomeric region|up regulation of establishment of protein localization to telomere|up-regulation of establishment of protein localisation to telomere|up regulation of establishment of protein localisation to telomere							nc	2015-12-10T15:37:58Z					biological_process											owl:Class	
GO:0070203	biolink:NamedThing	regulation of establishment of protein localization to telomere	Any process that modulates the frequency, rate or extent of the directed movement of a protein to a specific location in the telomeric region of a chromosome.	tmpzr1t_l9r_go_relaxed.owl	regulation of establishment of protein localisation to telomere													biological_process											owl:Class	
GO:0070308	biolink:NamedThing	lens fiber cell fate commitment	The process in which the developmental fate of a cell becomes restricted such that it will develop into a lens fiber cell. A lens fiber cell is any of the elongated, tightly packed cells that make up the bulk of the mature lens in a camera-type eye.	tmpzr1t_l9r_go_relaxed.owl	lens fibre cell fate commitment													biological_process											owl:Class	
GO:2000965	biolink:NamedThing	positive regulation of cellooligosaccharide catabolic process	Any process that activates or increases the frequency, rate or extent of cellooligosaccharide catabolic process.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of cellooligosaccharide catabolism							tt	2011-08-01T02:28:47Z					biological_process											owl:Class	
GO:2000963	biolink:NamedThing	regulation of cellooligosaccharide catabolic process	Any process that modulates the frequency, rate or extent of cellooligosaccharide catabolic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of cellooligosaccharide catabolism							tt	2011-08-01T02:28:36Z					biological_process											owl:Class	
GO:0043197	biolink:NamedThing	dendritic spine	A small, membranous protrusion from a dendrite that forms a postsynaptic compartment, typically receiving input from a single presynapse.  They function as partially isolated biochemical and an electrical compartments. Spine morphology is variable:they can be thin, stubby, mushroom, or  branched, with a continuum of intermediate morphologies. They typically terminate in a bulb shape, linked to the dendritic shaft by a restriction. Spine remodeling is though to be involved in synaptic plasticity.	tmpzr1t_l9r_go_relaxed.owl	stubby dendritic spine|sessile dendritic spine|dendrite spine|branched dendritic spine|thin dendritic spine|mushroom dendritic spine				NIF_Subcellular:sao1799103720|Wikipedia:Dendritic_spine									cellular_component											owl:Class	
GO:0046280	biolink:NamedThing	chalcone catabolic process	The chemical reactions and pathways resulting in the breakdown of chalcone, phenyl steryl ketone or its hydroxylated derivatives.	tmpzr1t_l9r_go_relaxed.owl	chalcone breakdown|chalcone catabolism|chalcone degradation													biological_process											owl:Class	
GO:0043767	biolink:NamedThing	pyrrolysyl-tRNA synthetase activity	Catalysis of the reaction: ATP + L-pyrrolysine + tRNA(Pyl) = AMP + diphosphate + L-pyrrolysyl-tRNA(Pyl).	tmpzr1t_l9r_go_relaxed.owl	PylRS|pyrrolysine-tRNA ligase activity				RHEA:19277|MetaCyc:6.1.1.26-RXN|EC:6.1.1.26									molecular_function											owl:Class	
GO:0046455	biolink:NamedThing	organosilicon catabolic process	The chemical reactions and pathways resulting in the breakdown of organosilicons, any organic compound that contains silicon.	tmpzr1t_l9r_go_relaxed.owl	organosilicon catabolism|organosilicon breakdown|organosilicone catabolic process|organosilicone catabolism|organosilicon degradation													biological_process											owl:Class	
GO:1900444	biolink:NamedThing	negative regulation of filamentous growth of a population of unicellular organisms in response to biotic stimulus	Any process that stops, prevents or reduces the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to biotic stimulus.	tmpzr1t_l9r_go_relaxed.owl	down regulation of filamentous growth of a population of unicellular organisms in response to biotic stimulus|downregulation of filamentous growth of a population of unicellular organisms in response to biotic stimulus|down-regulation of filamentous growth of a population of unicellular organisms in response to biotic stimulus|inhibition of filamentous growth of a population of unicellular organisms in response to biotic stimulus							di	2012-04-25T05:56:27Z					biological_process											owl:Class	
GO:1900429	biolink:NamedThing	negative regulation of filamentous growth of a population of unicellular organisms	Any process that stops, prevents or reduces the frequency, rate or extent of filamentous growth of a population of unicellular organisms.	tmpzr1t_l9r_go_relaxed.owl	down regulation of filamentous growth of a population of unicellular organisms|downregulation of filamentous growth of a population of unicellular organisms|inhibition of filamentous growth of a population of unicellular organisms|down-regulation of filamentous growth of a population of unicellular organisms							di	2012-04-25T05:53:43Z					biological_process											owl:Class	
GO:0045943	biolink:NamedThing	positive regulation of transcription by RNA polymerase I	Any process that activates or increases the frequency, rate or extent of transcription mediated by RNA polymerase I.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of transcription from RNA polymerase I promoter|positive regulation of transcription from Pol I promoter|up regulation of transcription from RNA polymerase I promoter|up-regulation of transcription from RNA polymerase I promoter|stimulation of transcription from RNA polymerase I promoter|activation of transcription from RNA polymerase I promoter|upregulation of transcription from RNA polymerase I promoter													biological_process											owl:Class	
GO:0008890	biolink:NamedThing	glycine C-acetyltransferase activity	Catalysis of the reaction: acetyl-CoA + glycine = L-2-amino-3-oxobutanoate + CoA + H(+).	tmpzr1t_l9r_go_relaxed.owl	2-amino-3-ketobutyrate coenzyme A ligase activity|aminoacetone synthase activity|2-amino-3-ketobutyrate CoA ligase activity|glycine acetyltransferase activity|acetyl-CoA:glycine C-acetyltransferase activity|2-amino-3-ketobutyrate-CoA ligase activity				KEGG_REACTION:R00371|RHEA:20736|EC:2.3.1.29|MetaCyc:AKBLIG-RXN									molecular_function											owl:Class	
GO:0003220	biolink:NamedThing	left ventricular cardiac muscle tissue morphogenesis	The process in which the anatomical structures of left cardiac ventricle muscle are generated and organized.	tmpzr1t_l9r_go_relaxed.owl	left ventricular myocardium morphogenesis							dph	2009-10-13T10:18:05Z					biological_process											owl:Class	
GO:0055010	biolink:NamedThing	ventricular cardiac muscle tissue morphogenesis	The process in which the anatomical structures of cardiac ventricle muscle is generated and organized.	tmpzr1t_l9r_go_relaxed.owl	ventricular heart muscle morphogenesis|cardiac ventricle muscle morphogenesis													biological_process											owl:Class	
GO:0016633	biolink:NamedThing	galactonolactone dehydrogenase activity	Catalysis of the reaction: L-galactono-1,4-lactone + 2 ferricytochrome c = L-ascorbate + 2 ferrocytochrome c.	tmpzr1t_l9r_go_relaxed.owl	GLDHase activity|L-galactonolactone dehydrogenase activity|GLDase activity|L-galactono-gamma-lactone:ferricytochrome-c oxidoreductase activity|L-galactono-1,4-lactone:ferricytochrome-c oxidoreductase activity|L-galactono-gamma-lactone dehydrogenase activity|L-galactono-1,4-lactone dehydrogenase activity				RHEA:32367|EC:1.3.2.3|MetaCyc:GALACTONOLACTONE-DEHYDROGENASE-RXN									molecular_function											owl:Class	
GO:0016632	biolink:NamedThing	oxidoreductase activity, acting on the CH-CH group of donors, cytochrome as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces a cytochrome.	tmpzr1t_l9r_go_relaxed.owl					EC:1.3.2.-									molecular_function											owl:Class	
GO:0044780	biolink:NamedThing	bacterial-type flagellum assembly	The assembly of a bacterial-type flagellum, a motor complex composed of an extracellular helical protein filament coupled to a rotary motor embedded in the cell envelope which functions in cell motility.	tmpzr1t_l9r_go_relaxed.owl	bacterial flagellum assembly							jl	2013-03-27T15:00:43Z					biological_process											owl:Class	
GO:0030031	biolink:NamedThing	cell projection assembly	Formation of a prolongation or process extending from a cell, e.g. a flagellum or axon.	tmpzr1t_l9r_go_relaxed.owl	formation of a cell surface projection|cell projection biogenesis													biological_process											owl:Class	
GO:2000094	biolink:NamedThing	negative regulation of mesonephric nephron tubule epithelial cell differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of mesonephric nephron tubule epithelial cell differentiation.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-09-03T06:12:28Z					biological_process											owl:Class	
GO:0009177	biolink:NamedThing	pyrimidine deoxyribonucleoside monophosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of pyrimidine deoxynucleoside monophosphate, a compound consisting of a pyrimidine base linked to a deoxyribose sugar esterified with phosphate on the sugar.	tmpzr1t_l9r_go_relaxed.owl	pyrimidine deoxyribonucleoside monophosphate anabolism|pyrimidine deoxyribonucleoside monophosphate biosynthesis|pyrimidine deoxyribonucleoside monophosphate synthesis|pyrimidine deoxyribonucleoside monophosphate formation													biological_process											owl:Class	
GO:0045671	biolink:NamedThing	negative regulation of osteoclast differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of osteoclast differentiation.	tmpzr1t_l9r_go_relaxed.owl	inhibition of osteoclast differentiation|down-regulation of osteoclast differentiation|down regulation of osteoclast differentiation|downregulation of osteoclast differentiation													biological_process											owl:Class	
GO:0045670	biolink:NamedThing	regulation of osteoclast differentiation	Any process that modulates the frequency, rate or extent of osteoclast differentiation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0016247	biolink:NamedThing	channel regulator activity	Bonds to and modulates the activity of a channel. A channel catalyzes energy-independent facilitated diffusion, mediated by passage of a solute through a transmembrane aqueous pore or channel.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1904772	biolink:NamedThing	response to tetrachloromethane	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tetrachloromethane stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to CCL4|response to carbon tetrachloride							sl	2015-10-28T20:59:15Z					biological_process											owl:Class	
GO:0055121	biolink:NamedThing	response to high fluence blue light stimulus by blue high-fluence system	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the detection of a high fluence blue light stimulus by the blue high-fluence system. Blue light is electromagnetic radiation with a wavelength of between 440 and 500nm. The blue high-fluence system responds to blue light at levels between 100 and 1000 micromols/m2.	tmpzr1t_l9r_go_relaxed.owl	response to high fluence blue light|response to high fluence blue light by bhf system													biological_process											owl:Class	
GO:0098941	biolink:NamedThing	anterograde trans-synaptic signaling by trans-synaptic protein complex	Cell-cell signaling from presynapse to postynapse, across the synaptic cleft, mediated by a trans-synaptic protein complex.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0099545	biolink:NamedThing	trans-synaptic signaling by trans-synaptic complex	Cell-cell signaling between presynapse and postsynapse mediated by a trans-synaptic protein complex.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0032242	biolink:NamedThing	regulation of nucleoside transport	Any process that modulates the frequency, rate or extent of the directed movement of a nucleoside into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0032246	biolink:NamedThing	regulation of pyrimidine nucleoside transport	Any process that modulates the frequency, rate or extent of the directed movement of a pyrimidine nucleoside into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0051201	biolink:NamedThing	negative regulation of prosthetic group metabolic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving a prosthetic group.	tmpzr1t_l9r_go_relaxed.owl	inhibition of prosthetic group metabolic process|negative regulation of coenzyme and prosthetic group metabolic process|down regulation of prosthetic group metabolic process|down-regulation of prosthetic group metabolic process|negative regulation of coenzyme and prosthetic group metabolism|negative regulation of prosthetic group metabolism|downregulation of prosthetic group metabolic process													biological_process											owl:Class	
GO:0009143	biolink:NamedThing	nucleoside triphosphate catabolic process	The chemical reactions and pathways resulting in the breakdown of a nucleoside triphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with triphosphate on the sugar.	tmpzr1t_l9r_go_relaxed.owl	nucleoside triphosphate degradation|nucleoside triphosphate catabolism|nucleoside triphosphate breakdown													biological_process											owl:Class	
GO:0102786	biolink:NamedThing	stearoyl-[acp] desaturase activity	Catalysis of the reaction: O2 + a stearoyl-[acp] + a reduced ferredoxin = 2 H2O + an oleoyl-[acp] + an oxidized ferredoxin.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-7903|RHEA:11776|EC:1.14.19.2									molecular_function											owl:Class	
GO:2000140	biolink:NamedThing	negative regulation of octopamine signaling pathway involved in response to food	Any process that stops, prevents, or reduces the frequency, rate or extent of octopamine signaling pathway involved in response to food.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of octopamine signalling pathway involved in response to food							mah	2010-09-30T02:48:10Z					biological_process											owl:Class	
GO:2000139	biolink:NamedThing	regulation of octopamine signaling pathway involved in response to food	Any process that modulates the frequency, rate or extent of octopamine signaling pathway involved in response to food.	tmpzr1t_l9r_go_relaxed.owl	regulation of octopamine signalling pathway involved in response to food							mah	2010-09-30T02:48:07Z					biological_process											owl:Class	
GO:0036212	biolink:NamedThing	contractile ring maintenance	The process in which the contractile ring is maintained, typically in response to an internal or external cue.	tmpzr1t_l9r_go_relaxed.owl						This term can be used to annotate maintenance of either bacterial or fungal contractile rings.		bf	2012-04-26T02:57:39Z					biological_process											owl:Class	
GO:0043954	biolink:NamedThing	cellular component maintenance	The organization process that preserves a cellular component in a stable functional or structural state.	tmpzr1t_l9r_go_relaxed.owl	cellular component maintenance at cellular level											GO:0071956		biological_process											owl:Class	
GO:0030416	biolink:NamedThing	methylamine metabolic process	The chemical reactions and pathways involving methylamine (CH3NH2).	tmpzr1t_l9r_go_relaxed.owl	methylammonium metabolism|methylamine metabolism|methylammonium metabolic process													biological_process											owl:Class	
GO:0007110	biolink:NamedThing	meiosis I cytokinesis	A cell cycle process that results in the division of the cytoplasm of a cell after meiosis I, resulting in the separation of the original cell into two daughter cells.	tmpzr1t_l9r_go_relaxed.owl	cytokinesis after meiosis I													biological_process											owl:Class	
GO:0010700	biolink:NamedThing	negative regulation of norepinephrine secretion	Any process that decreases the frequency, rate or extent of the regulated release of norepinephrine.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0030837	biolink:NamedThing	negative regulation of actin filament polymerization	Any process that stops, prevents, or reduces the frequency, rate or extent of actin polymerization.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of actin polymerization and/or depolymerization|downregulation of actin filament polymerization|negative regulation of actin polymerization|inhibition of actin filament polymerization|down regulation of actin filament polymerization|down-regulation of actin filament polymerization					Note that this term was split from 'negative regulation of actin polymerization and/or depolymerization ; GO:0045757' (sibling term 'negative regulation of actin depolymerization ; GO:0030835').								biological_process											owl:Class	
GO:0140361	biolink:NamedThing	cyclic-GMP-AMP transmembrane import across plasma membrane	The directed movement of cyclic-GMP-AMP from outside of a cell, across the plasma membrane and into the cytosol.	tmpzr1t_l9r_go_relaxed.owl								pg	2019-07-02T15:49:24Z					biological_process											owl:Class	
GO:0070729	biolink:NamedThing	cyclic nucleotide transport	The directed movement of a cyclic nucleotide, any nucleotide in which phosphate group is in diester linkage to two positions on the sugar residue, into, out of or within a cell.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-06-17T03:49:56Z					biological_process											owl:Class	
GO:0061641	biolink:NamedThing	CENP-A containing chromatin organization	Any process that results in the specification, formation or maintenance of the physical structure of CENP-A containing chromatin.	tmpzr1t_l9r_go_relaxed.owl	centromeric chromatin organization							dph	2014-08-27T12:26:14Z					biological_process											owl:Class	
GO:0097468	biolink:NamedThing	programmed cell death in response to reactive oxygen species	Cell death resulting from activation of endogenous cellular processes and occurring as a result of a reactive oxygen species stimulus. Reactive oxygen species include singlet oxygen, superoxide, and oxygen free radicals.	tmpzr1t_l9r_go_relaxed.owl	PCD in response to reactive oxygen species|reactive oxygen species-mediated programmed cell death|reactive oxygen species-mediated PCD|PCD in response to oxidative stress|programmed cell death in response to oxidative stress							pr	2013-02-19T10:03:36Z					biological_process											owl:Class	
GO:0009118	biolink:NamedThing	regulation of nucleoside metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nucleosides.	tmpzr1t_l9r_go_relaxed.owl	regulation of nucleoside metabolism													biological_process											owl:Class	
GO:0051498	biolink:NamedThing	syn-copalyl diphosphate synthase activity	Catalysis of the reaction: geranylgeranyl diphosphate = 9alpha-copalyl diphosphate.	tmpzr1t_l9r_go_relaxed.owl	diterpene cyclase activity				EC:5.5.1.14|MetaCyc:RXN-8528|RHEA:25524									molecular_function											owl:Class	
GO:0102936	biolink:NamedThing	gypsogenate-UDP-glucosyltransferase activity	Catalysis of the reaction: UDP-alpha-D-glucose + gypsogenate = gypsogenate-28-beta-D-glucoside + UDP.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-9013									molecular_function											owl:Class	
GO:0002645	biolink:NamedThing	positive regulation of tolerance induction	Any process that activates or increases the frequency, rate, or extent of tolerance induction.	tmpzr1t_l9r_go_relaxed.owl	up regulation of tolerance induction|upregulation of tolerance induction|stimulation of tolerance induction|activation of tolerance induction|up-regulation of tolerance induction													biological_process											owl:Class	
GO:0045785	biolink:NamedThing	positive regulation of cell adhesion	Any process that activates or increases the frequency, rate or extent of cell adhesion.	tmpzr1t_l9r_go_relaxed.owl	activation of cell adhesion|up-regulation of cell adhesion|stimulation of cell adhesion|up regulation of cell adhesion|upregulation of cell adhesion													biological_process											owl:Class	
GO:0008914	biolink:NamedThing	leucyltransferase activity	Catalysis of the reaction: L-leucyl-tRNA + protein = tRNA + L-leucyl-protein.	tmpzr1t_l9r_go_relaxed.owl	L-leucyl-tRNA:protein leucyltransferase activity|leucyl-tRNA--protein transferase activity|leucyl, phenylalanine-tRNA-protein transferase activity|L/F transferase activity|leucyl-phenylalanine-transfer ribonucleate-protein aminoacyltransferase activity|leucyl/phenylalanyl-tRNA--protein transferase activity|leucyl-phenylalanine-transfer ribonucleate-protein transferase activity				EC:2.3.2.6|MetaCyc:LEUCYLTRANSFERASE-RXN|RHEA:12340									molecular_function											owl:Class	
GO:0016755	biolink:NamedThing	aminoacyltransferase activity	Catalysis of the transfer of an amino-acyl group from one compound (donor) to another (acceptor).	tmpzr1t_l9r_go_relaxed.owl	transferase activity, transferring amino-acyl groups				EC:2.3.2.-									molecular_function											owl:Class	
GO:2001120	biolink:NamedThing	methanofuran biosynthetic process	The chemical reactions and pathways resulting in the formation of a methanofuran.	tmpzr1t_l9r_go_relaxed.owl	methanofuran biosynthesis							jl	2011-10-11T12:34:12Z					biological_process											owl:Class	
GO:0046835	biolink:NamedThing	carbohydrate phosphorylation	The process of introducing a phosphate group into a carbohydrate, any organic compound based on the general formula Cx(H2O)y.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0061372	biolink:NamedThing	activin receptor signaling pathway involved in heart jogging	A series of molecular signals initiated by the binding of a member of the activin family to a receptor on the surface of a target cell, and contributing to the process of heart jogging.	tmpzr1t_l9r_go_relaxed.owl	activin receptor signalling pathway involved in heart jogging							dph	2010-11-03T02:24:46Z					biological_process											owl:Class	
GO:0032924	biolink:NamedThing	activin receptor signaling pathway	A series of molecular signals initiated by the binding of an extracellular ligand to an activin receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.	tmpzr1t_l9r_go_relaxed.owl	activin receptor signalling pathway													biological_process											owl:Class	
GO:0005780	biolink:NamedThing	extrinsic component of intraperoxisomal membrane	The component of the intraperoxisomal membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.	tmpzr1t_l9r_go_relaxed.owl	extrinsic to intraperoxisomal membrane|intra-peroxisomal peripheral membrane													cellular_component											owl:Class	
GO:0051771	biolink:NamedThing	negative regulation of nitric-oxide synthase biosynthetic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of a nitric-oxide synthase enzyme.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of NO synthase biosynthesis|negative regulation of nitric-oxide synthase (type II) biosynthetic process|negative regulation of NOS biosynthetic process|inhibition of nitric-oxide synthase 2 biosynthetic process|down-regulation of nitric-oxide synthase biosynthetic process|downregulation of nitric-oxide synthase 2 biosynthetic process|inhibition of nitric-oxide synthase biosynthetic process|negative regulation of nitric-oxide synthase (type 2) biosynthesis|down regulation of nitric-oxide synthase biosynthetic process|negative regulation of nitric-oxide synthase (type II) biosynthesis|downregulation of nitric-oxide synthase biosynthetic process|down regulation of nitric-oxide synthase 2 biosynthetic process|negative regulation of NOS2 synthase biosynthetic process|negative regulation of NOS biosynthesis|negative regulation of NO synthase biosynthetic process|negative regulation of nitric-oxide synthase 2 biosynthetic process|negative regulation of NOS2 synthase biosynthesis|down-regulation of nitric-oxide synthase 2 biosynthetic process|negative regulation of nitric-oxide synthase (type 2) biosynthetic process											GO:0051774		biological_process											owl:Class	
GO:0030783	biolink:NamedThing	[cytochrome c]-methionine S-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + [cytochrome c]-methionine = S-adenosyl-L-homocysteine + [cytochrome c]-S-methyl-methionine.	tmpzr1t_l9r_go_relaxed.owl	S-adenosyl-L-methionine:cytochrome c-methionine S-methyltransferase activity|cytochrome c-methionine S-methyltransferase activity				EC:2.1.1.123|MetaCyc:2.1.1.123-RXN									molecular_function											owl:Class	
GO:0009815	biolink:NamedThing	1-aminocyclopropane-1-carboxylate oxidase activity	Catalysis of the reaction: 1-aminocyclopropane-1-carboxylate + L-ascorbate + O(2) = CO(2) + dehydroascorbate + ethylene + 2 H(2)O + hydrogen cyanide. Ethene is also known as ethylene.	tmpzr1t_l9r_go_relaxed.owl	1-aminocyclopropane-1-carboxylate oxygenase (ethylene-forming)|ACC oxidase activity|aminocyclopropanecarboxylate oxidase activity|ethene-forming enzyme|ethylene-forming enzyme				MetaCyc:ETHYL-RXN|RHEA:23640|KEGG_REACTION:R07214|EC:1.14.17.4									molecular_function											owl:Class	
GO:0140278	biolink:NamedThing	mitotic division septum assembly	The assembly and arrangement of a septum that spans the plasma membrane interface between progeny cells following mitotic cytokinesis. The progeny cells that form a division septum are not able to exchange intracellular material.	tmpzr1t_l9r_go_relaxed.owl								pg	2018-10-08T09:46:11Z					biological_process											owl:Class	
GO:0000917	biolink:NamedThing	division septum assembly	The assembly and arrangement of a septum that spans the plasma membrane interface between progeny cells following cytokinesis. The progeny cells that form a division septum are not able to exchange intracellular material.	tmpzr1t_l9r_go_relaxed.owl	septin assembly and septum formation involved in mitotic cell cycle|formation of division septum involved in mitotic cell cycle|division septum formation involved in cell cycle cytokinesis|septin assembly and septum biosynthesis involved in mitotic cell cycle|division septum formation involved in cell cycle cytokinesis involved in mitotic cell cycle|division septum assembly involved in cell cycle cytokinesis|division septum formation|division septum formation involved in mitotic cell cycle|division septum assembly involved in cell cycle cytokinesis involved in mitotic cell cycle|mitotic division septum assembly|septin assembly and septum formation|septin assembly and septum biosynthesis|formation of division septum|septation											GO:1902411|GO:0071937		biological_process											owl:Class	
GO:1902235	biolink:NamedThing	regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway	Any process that modulates the frequency, rate or extent of an endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	regulation of apoptosis triggered by ER stress|regulation of intrinsic apoptotic signaling pathway induced by endoplasmic reticulum stress|regulation of apoptosis in response to ER stress|regulation of apoptosis in response to endoplasmic reticulum stress|regulation of intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress|regulation of endoplasmic reticulum stress-induced apoptosis|regulation of ER stress-induced apoptosis							rl	2013-06-18T15:19:37Z					biological_process											owl:Class	
GO:0019504	biolink:NamedThing	stachydrine catabolic process	The chemical reactions and pathways resulting in the breakdown of stachydrine, N-methylproline methylbetaine, the betaine derivative of L-proline.	tmpzr1t_l9r_go_relaxed.owl	stachydrine catabolism|stachydrine degradation|stachydrine breakdown				MetaCyc:P561-PWY									biological_process											owl:Class	
GO:0006579	biolink:NamedThing	amino-acid betaine catabolic process	The chemical reactions and pathways resulting in the breakdown of any betaine, the N-trimethyl derivative of an amino acid.	tmpzr1t_l9r_go_relaxed.owl	betaine catabolic process|betaine catabolism|betaine breakdown|betaine degradation													biological_process											owl:Class	
GO:1905149	biolink:NamedThing	positive regulation of smooth muscle hypertrophy	Any process that activates or increases the frequency, rate or extent of smooth muscle hypertrophy.	tmpzr1t_l9r_go_relaxed.owl	up regulation of smooth muscle hypertrophy|upregulation of smooth muscle hypertrophy|up-regulation of smooth muscle hypertrophy|activation of smooth muscle hypertrophy							bc	2016-04-15T12:47:24Z					biological_process											owl:Class	
GO:0003270	biolink:NamedThing	Notch signaling pathway involved in regulation of secondary heart field cardioblast proliferation	The series of molecular signals initiated by binding of an extracellular ligand to a Notch receptor on the surface of the target cell contributing to the modulation of the frequency, rate or extent of cardioblast proliferation in the secondary heart field. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.	tmpzr1t_l9r_go_relaxed.owl	Notch signaling pathway involved in regulation of second heart field cardioblast proliferation|Notch signalling pathway involved in regulation of secondary heart field cardioblast proliferation							dph	2009-10-15T02:47:00Z					biological_process											owl:Class	
GO:0030843	biolink:NamedThing	negative regulation of intermediate filament depolymerization	Any process that stops, prevents, or reduces the frequency, rate or extent of intermediate filament depolymerization.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of intermediate filament depolymerization|negative regulation of intermediate filament polymerization and/or depolymerization|downregulation of intermediate filament depolymerization|down regulation of intermediate filament depolymerization|inhibition of intermediate filament depolymerization					Note that this term was split from 'negative regulation of intermediate filament polymerization and/or depolymerization ; GO:0045825' (sibling term 'negative regulation of intermediate filament polymerization ; GO:0030840').								biological_process											owl:Class	
GO:1901880	biolink:NamedThing	negative regulation of protein depolymerization	Any process that stops, prevents or reduces the frequency, rate or extent of protein depolymerization.	tmpzr1t_l9r_go_relaxed.owl	inhibition of protein polymer catabolism|down-regulation of protein polymer degradation|downregulation of protein polymer catabolic process|down-regulation of protein polymer catabolic process|downregulation of protein polymer degradation|inhibition of protein polymer catabolic process|negative regulation of protein polymer catabolism|down regulation of protein polymer breakdown|inhibition of protein polymer breakdown|inhibition of protein depolymerization|down-regulation of protein depolymerization|down regulation of protein depolymerization|down regulation of protein polymer catabolic process|negative regulation of protein polymer degradation|downregulation of protein depolymerization|down regulation of protein polymer degradation|negative regulation of protein polymer catabolic process|negative regulation of protein polymer breakdown|inhibition of protein polymer degradation|down-regulation of protein polymer breakdown|down regulation of protein polymer catabolism|downregulation of protein polymer catabolism|down-regulation of protein polymer catabolism|downregulation of protein polymer breakdown							rl	2013-02-06T13:57:28Z					biological_process											owl:Class	
GO:0070813	biolink:NamedThing	hydrogen sulfide metabolic process	The chemical reactions and pathways involving hydrogen sulfide, H2S.	tmpzr1t_l9r_go_relaxed.owl	hydrogen sulphide metabolic process|hydrogen sulphide metabolism|hydrogen sulfide metabolism							mah	2009-07-09T10:37:32Z					biological_process											owl:Class	
GO:0001994	biolink:NamedThing	norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure	A process that results in a decrease in the diameter of an artery during the norepinephrine-epinephrine response to decreased blood pressure.	tmpzr1t_l9r_go_relaxed.owl	norepinephrine-epinephrine vasoconstriction during blood pressure control|noradrenaline-adrenaline vasoconstriction involved in regulation of blood pressure|norepinephrine-epinephrine vasoconstriction during control of blood pressure|norepinephrine-epinephrine vasoconstriction during blood pressure regulation													biological_process											owl:Class	
GO:0047137	biolink:NamedThing	N-hydroxy-2-acetamidofluorene reductase activity	Catalysis of the reaction: 2-acetamidofluorene + NAD(P)+ + H2O = N-hydroxy-2-acetamidofluorene + NAD(P)H + H+.	tmpzr1t_l9r_go_relaxed.owl	NAD(P)H:N-hydroxy-2-acetamidofluorene N-oxidoreductase activity|N-hydroxy-2-acetylaminofluorene reductase activity|NAD(P)H2:N-hydroxy-2-acetamidofluorene N-oxidoreductase activity|2-acetamidofluorene:NAD(P)+ oxidoreductase activity				EC:1.7.1.12|MetaCyc:1.7.1.12-RXN									molecular_function											owl:Class	
GO:0038196	biolink:NamedThing	type III interferon signaling pathway	A series of molecular signals initiated by the binding of a type III interferon to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. Interferon lambda is the only member of the type III interferon found so far.	tmpzr1t_l9r_go_relaxed.owl	type III interferon-activated signaling pathway|interferon lambda signaling pathway							bf	2013-11-27T14:25:49Z					biological_process											owl:Class	
GO:0002247	biolink:NamedThing	clearance of damaged tissue involved in inflammatory response wound healing	The series of events leading to removal of necrotic debris that contribute to an inflammatory response.	tmpzr1t_l9r_go_relaxed.owl	clearance of damaged tissue during inflammatory response													biological_process											owl:Class	
GO:0004122	biolink:NamedThing	cystathionine beta-synthase activity	Catalysis of the reaction: L-serine + L-homocysteine = cystathionine + H2O.	tmpzr1t_l9r_go_relaxed.owl	serine sulfhydrylase activity|L-serine hydro-lyase (adding homocysteine; L-cystathionine-forming)|methylcysteine synthase activity|beta-thionase activity|L-serine hydro-lyase (adding homocysteine)|serine sulfhydrase activity				Reactome:R-HSA-1614524|MetaCyc:CYSTATHIONINE-BETA-SYNTHASE-RXN|RHEA:10112|EC:4.2.1.22									molecular_function											owl:Class	
GO:0010069	biolink:NamedThing	zygote asymmetric cytokinesis in embryo sac	The division of the zygote in a plane perpendicular to the long axis of the embryo sac to produce a larger basal cell near the micropyle and a small terminal cell close to what was the central cell and is now the developing endosperm. An example of this process is found in Arabidopsis thaliana.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0010070	biolink:NamedThing	zygote asymmetric cell division	The division of the zygote into two daughter cells that will adopt developmentally distinct potentials.	tmpzr1t_l9r_go_relaxed.owl	zygote asymmetric cytokinesis													biological_process											owl:Class	
GO:0034757	biolink:NamedThing	negative regulation of iron ion transport	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of iron ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of iron ion transport|inhibition of iron ion transport|downregulation of iron ion transport|down regulation of iron ion transport|negative regulation of iron transport													biological_process											owl:Class	
GO:1904056	biolink:NamedThing	positive regulation of cholangiocyte proliferation	Any process that activates or increases the frequency, rate or extent of cholangiocyte proliferation.	tmpzr1t_l9r_go_relaxed.owl	up regulation of cholangiocyte proliferation|upregulation of hepatoblast proliferation|up-regulation of hepatoblast proliferation|up-regulation of cholangiocyte proliferation|activation of cholangiocyte proliferation|activation of hepatoblast proliferation|up regulation of hepatoblast proliferation|upregulation of cholangiocyte proliferation|positive regulation of hepatoblast proliferation							sl	2015-03-18T17:56:26Z					biological_process											owl:Class	
GO:0070777	biolink:NamedThing	D-aspartate transport	The directed movement of D-aspartate, the D-enantiomer of the anion of (2R)-2-aminobutanedioic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-07-02T01:42:57Z					biological_process											owl:Class	
GO:0015740	biolink:NamedThing	C4-dicarboxylate transport	The directed movement of a C4-dicarboxylate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A C4-dicarboxylate is the anion of a dicarboxylic acid that contains four carbon atoms.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1902546	biolink:NamedThing	positive regulation of DNA N-glycosylase activity	Any process that activates or increases the frequency, rate or extent of DNA N-glycosylase activity.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of DNA glycosylase activity|up regulation of DNA glycosylase activity|upregulation of DNA glycosylase activity|upregulation of endonuclease VIII activity|activation of DNA glycosylase activity|up regulation of DNA N-glycosylase activity|positive regulation of DNA glycosylase activity|positive regulation of endonuclease VIII activity|activation of endonuclease VIII activity|up-regulation of DNA N-glycosylase activity|upregulation of DNA N-glycosylase activity|up-regulation of endonuclease VIII activity|up regulation of endonuclease VIII activity|activation of DNA N-glycosylase activity							rph	2013-12-04T14:18:12Z					biological_process											owl:Class	
GO:1902544	biolink:NamedThing	regulation of DNA N-glycosylase activity	Any process that modulates the frequency, rate or extent of DNA N-glycosylase activity.	tmpzr1t_l9r_go_relaxed.owl	regulation of endonuclease VIII activity|regulation of DNA glycosylase activity							rph	2013-12-04T14:17:54Z					biological_process											owl:Class	
GO:0051915	biolink:NamedThing	induction of synaptic plasticity by chemical substance	The process in which a chemical substance activates synaptic plasticity, the ability of synapses to change as circumstances require.	tmpzr1t_l9r_go_relaxed.owl	activation of synaptic plasticity by chemical substance|induction of synaptic plasticity by drug|activation of synaptic plasticity by drug													biological_process											owl:Class	
GO:0051914	biolink:NamedThing	positive regulation of synaptic plasticity by chemical substance	The process in which a chemical substance increases synaptic plasticity, the ability of synapses to change as circumstances require.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of synaptic plasticity by chemical substance|upregulation of synaptic plasticity by chemical substance|positive regulation of synaptic plasticity by drug|stimulation of synaptic plasticity by chemical substance|activation of synaptic plasticity by chemical substance|up regulation of synaptic plasticity by chemical substance													biological_process											owl:Class	
GO:0097535	biolink:NamedThing	lymphoid lineage cell migration into thymus	The movement of a lymphoid lineage cell (also called a lymphoid lineage restricted progenitor cell) into the thymus. Lymphoid lineage cells enter and exit the thymus several times as part of this process.	tmpzr1t_l9r_go_relaxed.owl	lymphoid lineage restricted progenitor cell migration into thymus							pr	2013-11-28T10:48:58Z					biological_process											owl:Class	
GO:0097534	biolink:NamedThing	lymphoid lineage cell migration	The orderly movement of a lymphoid lineage cell from one site to another. A lymphoid lineage cell, also called a lymphoid lineage restricted progenitor cell, is a progenitor cell restricted to the lymphoid lineage.	tmpzr1t_l9r_go_relaxed.owl	lymphoid lineage restricted progenitor cell migration							pr	2013-11-28T10:47:15Z					biological_process											owl:Class	
GO:0001966	biolink:NamedThing	thigmotaxis	The directed movement of a motile cell or organism in response to touch.	tmpzr1t_l9r_go_relaxed.owl	taxis in response to touch stimulus|taxis in response to mechanical stimulus|stereotaxis													biological_process											owl:Class	
GO:0042330	biolink:NamedThing	taxis	The directed movement of a motile cell or organism in response to an external stimulus.	tmpzr1t_l9r_go_relaxed.owl	directed movement in response to stimulus				Wikipedia:Taxis									biological_process											owl:Class	
GO:1900744	biolink:NamedThing	regulation of p38MAPK cascade	Any process that modulates the frequency, rate or extent of p38MAPK cascade.	tmpzr1t_l9r_go_relaxed.owl	regulation of p38 MAPK cascade|regulation of p38 cascade							pm	2012-05-28T02:40:14Z					biological_process											owl:Class	
GO:1900200	biolink:NamedThing	mesenchymal cell apoptotic process involved in metanephros development	Any mesenchymal cell apoptotic process that is involved in metanephros development.	tmpzr1t_l9r_go_relaxed.owl	mesenchymal cell apoptosis involved in metanephros development							yaf	2012-03-21T11:58:05Z					biological_process											owl:Class	
GO:0010966	biolink:NamedThing	regulation of phosphate transport	Any process that modulates the frequency, rate or extent of phosphate transport. Phosphate transport is the directed movement of phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-05-20T11:42:50Z					biological_process											owl:Class	
GO:0004451	biolink:NamedThing	isocitrate lyase activity	Catalysis of the reaction: isocitrate = glyoxylate + succinate.	tmpzr1t_l9r_go_relaxed.owl	ICL activity|isocitrase activity|isocitrate glyoxylate-lyase (succinate-forming)|isocitritase activity|isocitratase activity|threo-DS-isocitrate glyoxylate-lyase activity|isocitrate glyoxylate-lyase activity				MetaCyc:ISOCIT-CLEAV-RXN|KEGG_REACTION:R00479|EC:4.1.3.1|RHEA:13245									molecular_function											owl:Class	
GO:0047770	biolink:NamedThing	carboxylate reductase activity	Catalysis of the reaction: an aldehyde + acceptor + H2O = a carboxylate + reduced acceptor.	tmpzr1t_l9r_go_relaxed.owl	aldehyde:(acceptor) oxidoreductase activity|carboxylic acid reductase activity|aldehyde:acceptor oxidoreductase activity				EC:1.2.99.6|MetaCyc:CARBOXYLATE-REDUCTASE-RXN									molecular_function											owl:Class	
GO:0071728	biolink:NamedThing	beak development	The progression of the beak over time from its initial formation until its mature state. The avian beak is an external anatomical structure, in the head region, that is adapted for feeding self and young, catching prey, probing, etc. It encompasses, but is not restricted to, the maxilla, mandible, maxillary rhamphotheca, mandibular rhamphotheca, nostril, nasal fossa, nasal bones, egg tooth and rictus.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-03-17T03:52:48Z					biological_process											owl:Class	
GO:0042928	biolink:NamedThing	ferrichrome import into cell	A process in which ferrichrome is transported into the cell by specific cell surface receptors. Ferrichromes are any of a group of growth-promoting Fe(III) chelates formed by various genera of microfungi. They are homodetic cyclic hexapeptides made up of a tripeptide of glycine (or other small neutral amino acids) and a tripeptide of an N'acyl-N4-hydroxy-L-ornithine.	tmpzr1t_l9r_go_relaxed.owl	ferrichrome transport													biological_process											owl:Class	
GO:0015687	biolink:NamedThing	ferric-hydroxamate import into cell	A process in which ferric-hydroxamate, the iron-bound form of the iron chelator hydroxamate, is transported into the cell by specific cell surface receptors.	tmpzr1t_l9r_go_relaxed.owl	ferric-hydroxamate transport													biological_process											owl:Class	
GO:1903357	biolink:NamedThing	regulation of transcription initiation from RNA polymerase I promoter	Any process that modulates the frequency, rate or extent of transcription initiation from RNA polymerase I promoter.	tmpzr1t_l9r_go_relaxed.owl	regulation of transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript							mah	2014-08-21T10:19:32Z					biological_process											owl:Class	
GO:1902373	biolink:NamedThing	negative regulation of mRNA catabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of mRNA catabolic process.	tmpzr1t_l9r_go_relaxed.owl	down regulation of mRNA degradation|negative regulation of mRNA breakdown|downregulation of mRNA decay|down-regulation of mRNA catabolic process|down-regulation of mRNA decay|inhibition of mRNA breakdown|negative regulation of mRNA catabolism|inhibition of mRNA catabolic process|down-regulation of mRNA catabolism|down regulation of mRNA catabolic process|downregulation of mRNA catabolic process|downregulation of mRNA breakdown|down regulation of mRNA decay|down-regulation of mRNA degradation|negative regulation of mRNA degradation|inhibition of mRNA catabolism|inhibition of mRNA degradation|down-regulation of mRNA breakdown|negative regulation of mRNA decay|downregulation of mRNA catabolism|downregulation of mRNA degradation|down regulation of mRNA breakdown|down regulation of mRNA catabolism|inhibition of mRNA decay							bf	2013-08-22T15:16:19Z					biological_process											owl:Class	
GO:0047370	biolink:NamedThing	succinate-citramalate CoA-transferase activity	Catalysis of the reaction: S-citramalate + succinyl-CoA = citramalyl-CoA + succinate.	tmpzr1t_l9r_go_relaxed.owl	succinyl-CoA:citramalate CoA-transferase activity|citramalate coenzyme A-transferase activity|succinyl coenzyme A-citramalyl coenzyme A transferase activity|itaconate CoA-transferase activity				RHEA:38287|MetaCyc:2.8.3.7-RXN									molecular_function											owl:Class	
GO:0033730	biolink:NamedThing	arogenate dehydrogenase (NADP+) activity	Catalysis of the reaction: L-arogenate + NADP+ = L-tyrosine + NADPH + CO2.	tmpzr1t_l9r_go_relaxed.owl	TyrAAT2|L-arogenate:NADP+ oxidoreductase (decarboxylating) activity|arogenic dehydrogenase activity|TyrAAT1|TyrAa|pretyrosine dehydrogenase activity				RHEA:15417|EC:1.3.1.78|MetaCyc:1.3.1.78-RXN									molecular_function											owl:Class	
GO:1904005	biolink:NamedThing	regulation of phospholipase D activity	Any process that modulates the frequency, rate or extent of phospholipase D activity.	tmpzr1t_l9r_go_relaxed.owl	regulation of lecithinase D activity|regulation of lipophosphodiesterase II activity|regulation of phosphatidylcholine phosphatidohydrolase activity|regulation of choline phosphatase activity							sl	2015-03-06T17:20:05Z					biological_process											owl:Class	
GO:0010517	biolink:NamedThing	regulation of phospholipase activity	Any process that modulates the frequency, rate or extent of phospholipase activity, the hydrolysis of a phospholipid.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0000091	biolink:NamedThing	mitotic anaphase A	The cell cycle phase during which the kinetochore microtubules shorten as chromosomes move toward the spindle poles as part of mitosis.	tmpzr1t_l9r_go_relaxed.owl						Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).								biological_process											owl:Class	
GO:0000090	biolink:NamedThing	mitotic anaphase	The cell cycle phase during which chromosomes separate and migrate towards the poles of the spindle the as part of a mitotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl						Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).								biological_process											owl:Class	
GO:0033920	biolink:NamedThing	6-phospho-beta-galactosidase activity	Catalysis of the reaction: a 6-phospho-beta-D-galactoside + H2O = 6-phospho-D-galactose + an alcohol.	tmpzr1t_l9r_go_relaxed.owl	6-phospho-beta-D-galactosidase activity|beta-D-phosphogalactoside galactohydrolase activity|phospho-beta-D-galactosidase activity|6-phospho-beta-D-galactoside 6-phosphogalactohydrolase activity|phospho-beta-galactosidase activity				RHEA:24568|EC:3.2.1.85|MetaCyc:6-PHOSPHO-BETA-GALACTOSIDASE-RXN									molecular_function											owl:Class	
GO:1900720	biolink:NamedThing	negative regulation of uterine smooth muscle relaxation	Any process that stops, prevents or reduces the frequency, rate or extent of uterine smooth muscle relaxation.	tmpzr1t_l9r_go_relaxed.owl	downregulation of smooth muscle relaxation of the uterus|downregulation of uterine smooth muscle relaxation|down-regulation of uterine smooth muscle relaxation|down regulation of uterine smooth muscle relaxation|inhibition of uterine smooth muscle relaxation|down-regulation of smooth muscle relaxation of the uterus|negative regulation of smooth muscle relaxation of the uterus|inhibition of smooth muscle relaxation of the uterus|down regulation of smooth muscle relaxation of the uterus							jl	2012-05-24T03:12:49Z					biological_process											owl:Class	
GO:1901081	biolink:NamedThing	negative regulation of relaxation of smooth muscle	Any process that stops, prevents or reduces the frequency, rate or extent of relaxation of smooth muscle.	tmpzr1t_l9r_go_relaxed.owl	downregulation of relaxation of smooth muscle|inhibition of smooth muscle relaxation|inhibition of relaxation of smooth muscle|down regulation of smooth muscle relaxation|negative regulation of smooth muscle relaxation|down-regulation of relaxation of smooth muscle|down regulation of relaxation of smooth muscle|downregulation of smooth muscle relaxation|down-regulation of smooth muscle relaxation							jl	2012-07-04T10:45:31Z					biological_process											owl:Class	
GO:0070237	biolink:NamedThing	positive regulation of activation-induced cell death of T cells	Any process that activates or increases the frequency, rate or extent of activation-induced cell death of T cells.	tmpzr1t_l9r_go_relaxed.owl	upregulation of activation-induced cell death of T cells|up regulation of activation-induced cell death of T cells|positive regulation of activated T cell apoptosis|positive regulation of antigen-driven apoptosis|positive regulation of activation-induced cell death of T lymphocytes|up-regulation of activation-induced cell death of T cells|stimulation of activation-induced cell death of T cells|positive regulation of activation-induced cell death of T-lymphocytes|activation of activation-induced cell death of T cells|positive regulation of activation-induced cell death of T-cells|positive regulation of AICD													biological_process											owl:Class	
GO:1904898	biolink:NamedThing	negative regulation of hepatic stellate cell proliferation	Any process that stops, prevents or reduces the frequency, rate or extent of hepatic stellate cell proliferation.	tmpzr1t_l9r_go_relaxed.owl	down regulation of Ito cell proliferation|negative regulation of perisinusoidal cell proliferation|negative regulation of Ito cell proliferation|inhibition of hepatic perisinusoidal cell proliferation|down-regulation of hepatic stellate cell proliferation|downregulation of perisinusoidal cell proliferation|inhibition of perisinusoidal cell proliferation|downregulation of Ito cell proliferation|negative regulation of hepatic perisinusoidal cell proliferation|down regulation of hepatic stellate cell proliferation|downregulation of hepatic stellate cell proliferation|down-regulation of hepatic perisinusoidal cell proliferation|down regulation of perisinusoidal cell proliferation|inhibition of Ito cell proliferation|down-regulation of Ito cell proliferation|down-regulation of perisinusoidal cell proliferation|downregulation of hepatic perisinusoidal cell proliferation|inhibition of hepatic stellate cell proliferation|down regulation of hepatic perisinusoidal cell proliferation							sl	2016-01-14T15:57:06Z					biological_process											owl:Class	
GO:0036318	biolink:NamedThing	peptide pheromone receptor activity	Combining with a peptide pheromone, and transmitting the signal across the membrane to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl								bf	2012-08-30T16:45:14Z					molecular_function											owl:Class	
GO:0016503	biolink:NamedThing	pheromone receptor activity	Combining with a pheromone to initiate a change in cell activity. A pheromone is a substance used in olfactory communication between organisms of the same species eliciting a change in sexual or social behavior.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0005729	biolink:NamedThing	2-micrometer circle DNA	A plasmid commonly found in Saccharomyces, inherited in a non-Mendelian manner and often present in 100-400 copies.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0005727	biolink:NamedThing	extrachromosomal circular DNA	Circular DNA structures that are not part of a chromosome.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0010176	biolink:NamedThing	homogentisate phytyltransferase activity	Catalysis of the reaction: homogentisate + phytyl diphosphate + H+ = 2-methyl-6-phytyl-1,4-benzoquinone + CO2 + diphosphate. 2-methyl-6-phytyl-1,4-benzoquinone is also known as 2-methyl-6-phytylplastoquinol.	tmpzr1t_l9r_go_relaxed.owl					KEGG_REACTION:R07500|RHEA:37975|MetaCyc:RXN-2541									molecular_function											owl:Class	
GO:0010354	biolink:NamedThing	homogentisate prenyltransferase activity	Catalysis of the transfer of a prenyl group from one compound (donor) to homogentisic acid.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0071334	biolink:NamedThing	cellular response to rhamnose stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a rhamnose stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to L-rhamnose stimulus							mah	2009-12-10T05:38:38Z					biological_process											owl:Class	
GO:1903050	biolink:NamedThing	regulation of proteolysis involved in cellular protein catabolic process	Any process that modulates the frequency, rate or extent of proteolysis involved in cellular protein catabolic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of proteolysis during cellular protein catabolism|regulation of peptidolysis involved in cellular protein catabolism|regulation of peptidolysis involved in cellular protein catabolic process|regulation of peptidolysis during cellular protein catabolism|regulation of proteolysis during cellular protein catabolic process|regulation of peptidolysis during cellular protein catabolic process					overexpression of cathepsin C propeptide significantly increased the degradation of intestinal alkaline phosphatase (IAP)		rl	2014-05-22T18:00:45Z					biological_process											owl:Class	
GO:0010954	biolink:NamedThing	positive regulation of protein processing	Any process that increases the rate, frequency or extent of protein maturation by peptide bond cleavage.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of protein maturation by peptide bond cleavage							tb	2009-04-27T12:09:13Z					biological_process											owl:Class	
GO:0043839	biolink:NamedThing	lipid A phosphate methyltransferase activity	Catalysis of the transfer of a methyl group from S-adenosylmethionine (SAM) to the 1-phosphate group of lipid A.	tmpzr1t_l9r_go_relaxed.owl	lipid A methyltransferase|lipid A 1-phosphomethyltransferase activity|LmtA|lipid A phosphomethyltransferase activity													molecular_function											owl:Class	
GO:0031296	biolink:NamedThing	B cell costimulation	The process of providing, via surface-bound receptor-ligand pairs, a second, antigen-independent, signal in addition to that provided by the B cell receptor to augment B cell activation.	tmpzr1t_l9r_go_relaxed.owl	B lymphocyte co-stimulation|B lymphocyte costimulation|B-lymphocyte costimulation|B-lymphocyte co-stimulation|B-cell costimulation|B cell co-stimulation|B-cell co-stimulation													biological_process											owl:Class	
GO:0031294	biolink:NamedThing	lymphocyte costimulation	The process of providing, via surface-bound receptor-ligand pairs, a second, antigen-independent, signal in addition to that provided by the B- or T cell receptor to augment B- or T cell activation.	tmpzr1t_l9r_go_relaxed.owl	lymphocyte co-stimulation													biological_process											owl:Class	
GO:0060938	biolink:NamedThing	epicardium-derived cardiac fibroblast cell differentiation	The process in which an epicardial cell acquires the specialized structural and/or functional features of a cardiac fibroblast. A cardiac fibroblast is a connective tissue cell in the heart which secretes an extracellular matrix rich in collagen and other macromolecules.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-09-29T01:28:03Z					biological_process											owl:Class	
GO:0060935	biolink:NamedThing	cardiac fibroblast cell differentiation	The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cardiac fibroblast. A cardiac fibroblast is a connective tissue cell in the heart which secretes an extracellular matrix rich in collagen and other macromolecules.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-09-29T01:20:04Z					biological_process											owl:Class	
GO:0110074	biolink:NamedThing	positive regulation of apical constriction involved in ventral furrow formation	Any process that activates or increases the frequency, rate or extent of apical constriction involved in ventral furrow formation.	tmpzr1t_l9r_go_relaxed.owl								kmv	2017-12-06T17:39:00Z					biological_process											owl:Class	
GO:1900571	biolink:NamedThing	diorcinol catabolic process	The chemical reactions and pathways resulting in the breakdown of diorcinol.	tmpzr1t_l9r_go_relaxed.owl	diorcinol breakdown|diorcinol catabolism|diorcinol degradation							di	2012-05-15T06:35:22Z					biological_process											owl:Class	
GO:2000742	biolink:NamedThing	regulation of anterior head development	Any process that modulates the frequency, rate or extent of anterior head development.	tmpzr1t_l9r_go_relaxed.owl								yaf	2011-06-14T09:44:09Z					biological_process											owl:Class	
GO:0038174	biolink:NamedThing	interleukin-17A receptor activity	Combining with the cytokine interleukin-17A and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl								bf	2012-06-12T11:01:25Z					molecular_function											owl:Class	
GO:0030368	biolink:NamedThing	interleukin-17 receptor activity	Combining with any member of the interleukin-17 family of cytokines and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	IL-17 receptor activity|IL-17R				Wikipedia:Interleukin-17_receptor									molecular_function											owl:Class	
GO:0031758	biolink:NamedThing	Edg-5 sphingosine 1-phosphate receptor binding	Binding to an Edg-5 sphingosine 1-phosphate receptor.	tmpzr1t_l9r_go_relaxed.owl	Edg-5 sphingosine 1-phosphate receptor ligand													molecular_function											owl:Class	
GO:1904879	biolink:NamedThing	positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel	Any process that activates or increases the frequency, rate or extent of calcium ion transmembrane transport via high voltage-gated calcium channel.	tmpzr1t_l9r_go_relaxed.owl	upregulation of generation of L-type calcium current|positive regulation of generation of L-type calcium current|up-regulation of generation of L-type calcium current|up regulation of generation of L-type calcium current|activation of generation of L-type calcium current							sl	2015-12-18T22:30:44Z					biological_process											owl:Class	
GO:1902514	biolink:NamedThing	regulation of calcium ion transmembrane transport via high voltage-gated calcium channel	Any process that modulates the frequency, rate or extent of generation of calcium ion transmembrane transport via high voltage-gated calcium channel.	tmpzr1t_l9r_go_relaxed.owl	regulation of generation of L-type calcium current							dph	2013-11-16T00:04:42Z					biological_process											owl:Class	
GO:2000868	biolink:NamedThing	negative regulation of estrone secretion	Any process that stops, prevents or reduces the frequency, rate or extent of estrone secretion.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of 3-hydroxy-1,3,5(10)-estratrien-17-one secretion|negative regulation of folliculin secretion							bf	2011-07-26T08:50:16Z					biological_process											owl:Class	
GO:0032544	biolink:NamedThing	plastid translation	The chemical reactions and pathways resulting in the formation of a protein in a plastid. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein; the plastid has its own ribosomes and transfer RNAs, and uses a genetic code that differs from the nuclear code.	tmpzr1t_l9r_go_relaxed.owl	plastid protein translation|plastid protein biosynthesis|plastid protein formation|plastid protein anabolism|plastid protein synthesis													biological_process											owl:Class	
GO:1900396	biolink:NamedThing	positive regulation of kojic acid biosynthetic process	Any process that activates or increases the frequency, rate or extent of kojic acid biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	activation of kojic acid synthesis|upregulation of kojic acid formation|activation of kojic acid formation|up regulation of kojic acid biosynthetic process|up-regulation of kojic acid formation|upregulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one formation|upregulation of C6H6O4 biosynthesis|up regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one biosynthesis|up-regulation of kojic acid synthesis|upregulation of kojic acid biosynthesis|up-regulation of C6H6O4 synthesis|upregulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one biosynthetic process|positive regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one biosynthetic process|activation of kojic acid biosynthesis|up-regulation of C6H6O4 biosynthesis|activation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one formation|up regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one synthesis|up regulation of C6H6O4 biosynthesis|activation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one anabolism|up-regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one formation|activation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one synthesis|positive regulation of kojic acid anabolism|up-regulation of C6H6O4 anabolism|up-regulation of kojic acid biosynthesis|activation of C6H6O4 biosynthesis|positive regulation of C6H6O4 biosynthesis|up regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one anabolism|positive regulation of C6H6O4 biosynthetic process|activation of C6H6O4 formation|positive regulation of C6H6O4 formation|up regulation of C6H6O4 synthesis|upregulation of kojic acid anabolism|up-regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one anabolism|up regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one biosynthetic process|activation of C6H6O4 anabolism|upregulation of C6H6O4 anabolism|up regulation of kojic acid formation|activation of kojic acid anabolism|activation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one biosynthesis|activation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one biosynthetic process|up regulation of C6H6O4 anabolism|up-regulation of C6H6O4 formation|activation of C6H6O4 synthesis|positive regulation of C6H6O4 synthesis|upregulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one synthesis|up regulation of kojic acid anabolism|up-regulation of kojic acid anabolism|upregulation of C6H6O4 biosynthetic process|positive regulation of kojic acid synthesis|positive regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one biosynthesis|positive regulation of kojic acid biosynthesis|upregulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one anabolism|positive regulation of kojic acid formation|up regulation of C6H6O4 biosynthetic process|upregulation of kojic acid synthesis|up regulation of kojic acid synthesis|activation of C6H6O4 biosynthetic process|up regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one formation|up regulation of kojic acid biosynthesis|upregulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one biosynthesis|positive regulation of C6H6O4 anabolism|positive regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one anabolism|positive regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one formation|up-regulation of kojic acid biosynthetic process|positive regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one synthesis|activation of kojic acid biosynthetic process|up-regulation of C6H6O4 biosynthetic process|up-regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one synthesis|up regulation of C6H6O4 formation|upregulation of C6H6O4 formation|up-regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one biosynthetic process|up-regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one biosynthesis|upregulation of C6H6O4 synthesis|upregulation of kojic acid biosynthetic process							di	2012-04-18T04:20:11Z					biological_process											owl:Class	
GO:1902932	biolink:NamedThing	positive regulation of alcohol biosynthetic process	Any process that activates or increases the frequency, rate or extent of alcohol biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	upregulation of alcohol anabolism|positive regulation of alcohol biosynthesis|up regulation of alcohol synthesis|up-regulation of alcohol formation|activation of alcohol formation|positive regulation of alcohol synthesis|positive regulation of alcohol formation|activation of alcohol synthesis|up-regulation of alcohol anabolism|up regulation of alcohol biosynthetic process|upregulation of alcohol formation|up-regulation of alcohol biosynthetic process|upregulation of alcohol synthesis|positive regulation of alcohol anabolism|up-regulation of alcohol biosynthesis|activation of alcohol biosynthesis|up regulation of alcohol biosynthesis|up-regulation of alcohol synthesis|up regulation of alcohol formation|up regulation of alcohol anabolism|upregulation of alcohol biosynthesis|positive regulation of solventogenesis|upregulation of alcohol biosynthetic process|activation of alcohol biosynthetic process|activation of alcohol anabolism							tt	2014-04-22T21:55:19Z					biological_process											owl:Class	
GO:1990438	biolink:NamedThing	U6 2'-O-snRNA methylation	The posttranscriptional addition a methyl group to the 2'-oxygen atom of a nucleotide residue in an U6 snRNA molecule.	tmpzr1t_l9r_go_relaxed.owl								mah	2014-07-31T12:04:21Z					biological_process											owl:Class	
GO:1990437	biolink:NamedThing	snRNA 2'-O-methylation	The posttranscriptional addition of a methyl group to the 2' oxygen atom of a nucleotide residue in an snRNA molecule.	tmpzr1t_l9r_go_relaxed.owl								mah	2014-07-31T11:58:18Z					biological_process											owl:Class	
GO:0098696	biolink:NamedThing	regulation of neurotransmitter receptor localization to postsynaptic specialization membrane	Any process that modulates the frequency, rate or extent of neurotransmitter receptor localization to postsynaptic specialization membrane.	tmpzr1t_l9r_go_relaxed.owl								dos	2017-04-04T16:33:38Z					biological_process											owl:Class	
GO:0002034	biolink:NamedThing	maintenance of blood vessel diameter homeostasis by renin-angiotensin	The process in which the diameter of a blood vessel is changed due to activity of the renin-angiotensin system.	tmpzr1t_l9r_go_relaxed.owl	renin-angiotensin regulation of blood vessel size|regulation of blood vessel size by renin-angiotensin|regulation of blood vessel diameter by renin-angiotensin	https://github.com/geneontology/go-ontology/issues/12253												biological_process											owl:Class	
GO:0003072	biolink:NamedThing	renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure	The renal process that modulates the force with which blood travels through the circulatory system, by impeding blood flow through the peripheral vasculature.	tmpzr1t_l9r_go_relaxed.owl	renal regulation of systemic arterial blood pressure by control of peripheral vascular resistence|regulation of systemic arterial blood pressure by renal control of peripheral vascular resistence													biological_process											owl:Class	
GO:0097499	biolink:NamedThing	protein localization to non-motile cilium	A process in which a protein is transported to, or maintained in, a location within a non-motile cilium.	tmpzr1t_l9r_go_relaxed.owl	protein localization to nonmotile primary cilium							pr	2013-08-13T12:16:26Z					biological_process											owl:Class	
GO:0051340	biolink:NamedThing	regulation of ligase activity	Any process that modulates the frequency, rate or extent of ligase activity, the catalysis of the ligation of two substances with concomitant breaking of a diphosphate linkage, usually in a nucleoside triphosphate. Ligase is the systematic name for any enzyme of EC class 6.	tmpzr1t_l9r_go_relaxed.owl	ligase regulator													biological_process											owl:Class	
GO:2001314	biolink:NamedThing	UDP-4-deoxy-4-formamido-beta-L-arabinopyranose catabolic process	The chemical reactions and pathways resulting in the breakdown of a UDP-4-deoxy-4-formamido-beta-L-arabinopyranose.	tmpzr1t_l9r_go_relaxed.owl	UDP-4-deoxy-4-formamido-beta-L-arabinopyranose breakdown|UDP-4-deoxy-4-formamido-beta-L-arabinopyranose catabolism|UDP-4-deoxy-4-formamido-beta-L-arabinopyranose degradation							pr	2012-03-22T01:20:01Z					biological_process											owl:Class	
GO:2001108	biolink:NamedThing	positive regulation of Rho guanyl-nucleotide exchange factor activity	Any process that activates or increases the frequency, rate or extent of Rho guanyl-nucleotide exchange factor activity.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of RhoGEF|positive regulation of Rho guanine nucleotide exchange factor							yaf	2011-09-23T10:13:16Z					biological_process											owl:Class	
GO:1905099	biolink:NamedThing	positive regulation of guanyl-nucleotide exchange factor activity	Any process that activates or increases the frequency, rate or extent of guanyl-nucleotide exchange factor activity.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of guanyl-nucleotide releasing factor|positive regulation of GDP-dissociation stimulator activity|positive regulation of GEF|upregulation of GNRP|activation of GEF|up regulation of guanyl-nucleotide release factor activity|up regulation of guanyl-nucleotide exchange factor activity|up regulation of GEF|upregulation of GDP-dissociation stimulator activity|up-regulation of GNRP|positive regulation of GDS|up-regulation of guanyl-nucleotide releasing factor|up-regulation of GDP-dissociation stimulator activity|upregulation of guanyl-nucleotide releasing factor|activation of guanyl-nucleotide release factor activity|up-regulation of guanyl-nucleotide release factor activity|up regulation of GDS|positive regulation of GNRP|up regulation of GNRP|upregulation of GDS|activation of guanyl-nucleotide exchange factor activity|upregulation of guanyl-nucleotide release factor activity|upregulation of GEF|up-regulation of GDS|up regulation of GDP-dissociation stimulator activity|up-regulation of GEF|activation of guanyl-nucleotide releasing factor|up-regulation of guanyl-nucleotide exchange factor activity|activation of GDP-dissociation stimulator activity|activation of GDS|activation of GNRP|up regulation of guanyl-nucleotide releasing factor|upregulation of guanyl-nucleotide exchange factor activity|positive regulation of guanyl-nucleotide release factor activity	https://github.com/geneontology/go-ontology/issues/18750						sl	2016-03-31T16:09:54Z					biological_process											owl:Class	
GO:0009341	biolink:NamedThing	beta-galactosidase complex	A protein complex that possesses beta-galactosidase activity, i.e. catalyzes the hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides. In E. coli, the complex is a homotetramer; dimeric and hexameric beta-galactosidase complexes have been observed in other species.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0015844	biolink:NamedThing	monoamine transport	The directed movement of monoamines, organic compounds that contain one amino group that is connected to an aromatic ring by an ethylene group (-CH2-CH2-), into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl												GO:0015873		biological_process											owl:Class	
GO:0042489	biolink:NamedThing	negative regulation of odontogenesis of dentin-containing tooth	Any process that stops, prevents, or reduces the frequency, rate or extent of the formation and development of teeth, the hard, bony appendages which are borne on the jaws, or on other bones in the walls of the mouth or pharynx.	tmpzr1t_l9r_go_relaxed.owl	downregulation of odontogenesis|down regulation of odontogenesis|negative regulation of odontogenesis|inhibition of odontogenesis|negative regulation of odontogenesis of dentine-containing tooth|negative regulation of odontogenesis of dentine-containing teeth|down-regulation of odontogenesis													biological_process											owl:Class	
GO:0042483	biolink:NamedThing	negative regulation of odontogenesis	Any process that stops, prevents, or reduces the frequency, rate or extent of the formation and development of a tooth or teeth.	tmpzr1t_l9r_go_relaxed.owl	inhibition of odontogenesis|negative regulation of odontogenesis of calcareous or chitinous tooth|down-regulation of odontogenesis|downregulation of odontogenesis|down regulation of odontogenesis|negative regulation of tooth development											GO:0042486		biological_process											owl:Class	
GO:1900381	biolink:NamedThing	positive regulation of asperthecin biosynthetic process	Any process that activates or increases the frequency, rate or extent of asperthecin biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of asperthecin biosynthesis|activation of asperthecin biosynthesis|activation of asperthecin formation|up-regulation of asperthecin biosynthetic process|upregulation of asperthecin formation|up regulation of asperthecin formation|activation of asperthecin biosynthetic process|positive regulation of asperthecin synthesis|up regulation of asperthecin biosynthesis|up regulation of asperthecin biosynthetic process|up-regulation of asperthecin biosynthesis|upregulation of asperthecin biosynthetic process|upregulation of asperthecin synthesis|up-regulation of asperthecin synthesis|activation of asperthecin synthesis|up regulation of asperthecin synthesis|upregulation of asperthecin biosynthesis|up-regulation of asperthecin formation|positive regulation of asperthecin formation							di	2012-04-17T01:58:45Z					biological_process											owl:Class	
GO:0047216	biolink:NamedThing	inositol 3-alpha-galactosyltransferase activity	Catalysis of the reaction: myo-inositol + UDP-galactose = O-alpha-D-galactosyl-(1,3)-1D-myo-inositol + UDP.	tmpzr1t_l9r_go_relaxed.owl	UDP-galactose:myo-inositol 1-alpha-D-galactosyltransferase activity|UDP-D-galactose:inositol galactosyltransferase activity|uridine diphosphogalactose-inositol galactosyltransferase activity|UDP-galactose:myo-inositol 3-alpha-D-galactosyltransferase activity|UDPgalactose:myo-inositol 1-alpha-D-galactosyltransferase activity|galactinol synthase activity|inositol 1-alpha-galactosyltransferase activity				EC:2.4.1.123|RHEA:12464|MetaCyc:2.4.1.123-RXN									molecular_function											owl:Class	
GO:0004931	biolink:NamedThing	extracellularly ATP-gated cation channel activity	Enables the transmembrane transfer of a cation by a channel that opens when ATP is bound by the channel complex or one of its constituent parts on the extracellular side of the plasma membrane.	tmpzr1t_l9r_go_relaxed.owl	purinoceptor|purinoreceptor|P2X receptor				Reactome:R-HSA-877187	Note that this term refers to an activity and not a gene product. Consider also annotating to the molecular function term 'purinergic nucleotide receptor activity ; GO:0001614'.								molecular_function											owl:Class	
GO:0032406	biolink:NamedThing	MutLbeta complex binding	Binding to a MutLbeta mismatch repair complex.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0032404	biolink:NamedThing	mismatch repair complex binding	Binding to a mismatch repair complex.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0016131	biolink:NamedThing	brassinosteroid metabolic process	The chemical reactions and pathways involving brassinosteroids, any of a group of steroid derivatives that occur at very low concentrations in plant tissues and may have hormone-like effects.	tmpzr1t_l9r_go_relaxed.owl	brassinosteroid metabolism													biological_process											owl:Class	
GO:0042445	biolink:NamedThing	hormone metabolic process	The chemical reactions and pathways involving any hormone, naturally occurring substances secreted by specialized cells that affects the metabolism or behavior of other cells possessing functional receptors for the hormone.	tmpzr1t_l9r_go_relaxed.owl	hormone metabolism													biological_process											owl:Class	
GO:0071231	biolink:NamedThing	cellular response to folic acid	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a folic acid stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to vitamin B9|response to folate							mah	2009-12-03T02:08:32Z					biological_process											owl:Class	
GO:1904710	biolink:NamedThing	positive regulation of granulosa cell apoptotic process	Any process that activates or increases the frequency, rate or extent of granulosa cell apoptotic process.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of granulosa cell of ovary apoptotic process|up regulation of granulosa cell of ovary apoptosis|up regulation of granulosa cell of ovary apoptotic process|up regulation of granulosa cell apoptotic process|up-regulation of granulosa cell of ovary apoptosis|up-regulation of granulosa cell apoptotic process|upregulation of granulosa cell of ovary apoptotic process|positive regulation of granulosa cell apoptosis|up-regulation of granulosa cell of ovary apoptotic process|positive regulation of granulosa cell of ovary apoptosis|activation of granulosa cell of ovary apoptotic process|upregulation of granulosa cell of ovary apoptosis|activation of granulosa cell apoptotic process|upregulation of granulosa cell apoptotic process|activation of granulosa cell apoptosis|upregulation of granulosa cell apoptosis|up-regulation of granulosa cell apoptosis|up regulation of granulosa cell apoptosis|activation of granulosa cell of ovary apoptosis							sl	2015-10-01T16:09:51Z					biological_process											owl:Class	
GO:0060347	biolink:NamedThing	heart trabecula formation	The process of creating a trabecula in the heart. A trabecula is a tissue element in the form of a small beam, strut or rod.	tmpzr1t_l9r_go_relaxed.owl	heart trabecula biogenesis|cardiac trabeculation|cardiac trabecula formation|heart trabeculation													biological_process											owl:Class	
GO:0102754	biolink:NamedThing	chlorophyllide-b:phytyl-diphosphate phytyltransferase activity	Catalysis of the reaction: H+ + chlorophyllide b + (E)-3,7,11,15-tetramethylhexadec-2-en-1-yl diphosphate <=> chlorophyll b + diphosphoric acid.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-7674									molecular_function											owl:Class	
GO:0021742	biolink:NamedThing	abducens nucleus development	The process whose specific outcome is the progression of the abducens nucleus over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0032239	biolink:NamedThing	regulation of nucleobase-containing compound transport	Any process that modulates the frequency, rate or extent of the directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport													biological_process											owl:Class	
GO:1900763	biolink:NamedThing	averantin biosynthetic process	The chemical reactions and pathways resulting in the formation of averantin.	tmpzr1t_l9r_go_relaxed.owl	averantin synthesis|averantin formation|averantin biosynthesis|averantin anabolism							di	2012-06-04T09:14:52Z					biological_process											owl:Class	
GO:0043305	biolink:NamedThing	negative regulation of mast cell degranulation	Any process that stops, prevents, or reduces the rate of mast cell degranulation.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of mast cell granule exocytosis|downregulation of mast cell degranulation|down-regulation of mast cell degranulation|down regulation of mast cell degranulation|inhibition of mast cell degranulation													biological_process											owl:Class	
GO:2000797	biolink:NamedThing	regulation of amniotic stem cell differentiation	Any process that modulates the frequency, rate or extent of amniotic stem cell differentiation.	tmpzr1t_l9r_go_relaxed.owl								yaf	2011-06-29T02:18:59Z					biological_process											owl:Class	
GO:0034030	biolink:NamedThing	ribonucleoside bisphosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of a ribonucleoside bisphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar.	tmpzr1t_l9r_go_relaxed.owl	ribonucleoside bisphosphate anabolism|ribonucleoside bisphosphate synthesis|ribonucleoside bisphosphate formation|ribonucleoside bisphosphate biosynthesis													biological_process											owl:Class	
GO:2000336	biolink:NamedThing	negative regulation of endothelial microparticle formation	Any process that stops, prevents or reduces the frequency, rate or extent of endothelial microparticle formation.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of endothelial microparticle generation|negative regulation of endothelial microparticle release							mah	2011-01-31T11:20:33Z					biological_process											owl:Class	
GO:0120193	biolink:NamedThing	tight junction organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a tight junction. A tight junction seals cells together in an epithelium in a way that prevents even small molecules from leaking from one side of the sheet to the other.	tmpzr1t_l9r_go_relaxed.owl	occluding junction organization|occluding cell junction organization							krc	2018-08-14T23:05:40Z					biological_process											owl:Class	
GO:1904238	biolink:NamedThing	pericyte cell differentiation	The process in which a relatively unspecialized cell acquires the specialized features of a pericyte cell.	tmpzr1t_l9r_go_relaxed.owl								dph	2015-05-15T14:50:13Z					biological_process											owl:Class	
GO:0019784	biolink:NamedThing	NEDD8-specific protease activity	Catalysis of the hydrolysis of NEDD8, a small ubiquitin-related modifier, from previously neddylated substrates.	tmpzr1t_l9r_go_relaxed.owl	deneddylase activity				Reactome:R-HSA-8956040|Reactome:R-HSA-8863723|Reactome:R-HSA-5690808|Reactome:R-HSA-8956045									molecular_function											owl:Class	
GO:0019783	biolink:NamedThing	ubiquitin-like protein-specific protease activity	Catalysis of the hydrolysis of peptide or isopeptide bonds within small proteins such as ubiquitin or ubiquitin-like proteins (e.g. APG8, ISG15, NEDD8, SUMO), or between the small protein and a larger protein to which it has been conjugated.	tmpzr1t_l9r_go_relaxed.owl	ubiquitin-like specific protease activity|ubiquitin-like-protein-specific protease activity|small conjugating protein-specific protease activity|ubiquitin-specific protease activity involved in positive regulation of ERAD pathway|ubiquitin-specific protease activity involved in negative regulation of ERAD pathway											GO:1904454|GO:1904455		molecular_function											owl:Class	
GO:0002110	biolink:NamedThing	cotranscriptional mitochondrial rRNA nucleotide insertion	The insertion of one or two non-coded nucleotides during the transcription of a mitochondrial rRNA. Such additions are known to occur in myxomycetes such as Physarum, Didymium, and Stemonitis.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0070705	biolink:NamedThing	RNA nucleotide insertion	The modification of an RNA molecule by insertion of one or more nucleotides.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-06-08T04:48:35Z					biological_process											owl:Class	
GO:0035835	biolink:NamedThing	indole alkaloid biosynthetic process	The chemical reactions and pathways resulting in the formation of an indole alkaloid, an alkaloid containing an indole skeleton.	tmpzr1t_l9r_go_relaxed.owl	indole alkaloid formation|indole alkaloid synthesis|indole alkaloid biosynthesis|indole alkaloid anabolism							bf	2011-05-04T03:18:31Z					biological_process											owl:Class	
GO:1904447	biolink:NamedThing	folate import across plasma membrane	The directed movement of folic acid from outside of a cell, across the plasma membrane and into the cytosol.	tmpzr1t_l9r_go_relaxed.owl	folic acid import across plasma membrane|folate import into cell							hal	2015-07-07T15:32:33Z					biological_process											owl:Class	
GO:0014893	biolink:NamedThing	response to rest involved in regulation of muscle adaptation	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a rest stimulus. This process occurs as part of the regulation of muscle adaptation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0014877	biolink:NamedThing	response to muscle inactivity involved in regulation of muscle adaptation	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a muscle inactivity stimulus. This process occurs as part of the regulation of muscle adaptation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0103039	biolink:NamedThing	protein methylthiotransferase activity	Catalysis of the reaction: 2 S-adenosyl-L-methionine  + a [ribosomal protein S12] L-aspartate89 + a sulfurated [sulfur carrier] + a reduced electron acceptor = S-adenosyl-L-homocysteine  + L-methionine  + 5'-deoxyadenosine + 2 H+ + a [ribosomal protein S12] 3-methylthio-L-aspartate89 + an unsulfurated [sulfur carrier] + an oxidized electron acceptor.	tmpzr1t_l9r_go_relaxed.owl					RHEA:37087|MetaCyc:RXN0-6366|EC:2.8.4.4									molecular_function											owl:Class	
GO:0039664	biolink:NamedThing	lysis of host organelle involved in viral entry into host cell	The viral-induced lysis of an organelle (endosome, lysosome, or caveosome) that is involved in the uptake of a virus into a host cell. Occurs once the virus is within the organelle, and results in transfer of the viral contents from the organelle compartment into the cytoplasm.	tmpzr1t_l9r_go_relaxed.owl	viral entry into host cell via endosome membrane lysis|viral entry into host cell via lysis of host organelle membrane|viral penetration via lysis of host organellar membrane|viral membrane-lytic protein				VZ:984			bf	2013-08-29T11:30:18Z					biological_process											owl:Class	
GO:0097621	biolink:NamedThing	monoamine oxidase activity	Catalysis of the reaction: RCH2NHR' + H2O + O2 = RCHO + R'NH2 + H2O2.	tmpzr1t_l9r_go_relaxed.owl	amine:oxygen oxidoreductase (deaminating) activity				RHEA:26414|EC:1.4.3.4	Acts on primary amines, and also on some secondary and tertiary amines. It differs from EC:1.4.3.21, primary-amine oxidase as it can oxidize secondary and tertiary amines but not methylamine.		pr	2014-07-30T10:23:57Z					molecular_function											owl:Class	
GO:0003132	biolink:NamedThing	mesodermal-endodermal cell signaling involved in heart induction	Any process that mediates the transfer of information from mesodermal cells to endodermal cells that contributes to heart induction.	tmpzr1t_l9r_go_relaxed.owl	mesodermal-endodermal cell signalling involved in heart induction							tb	2009-09-22T03:08:52Z					biological_process											owl:Class	
GO:0003131	biolink:NamedThing	mesodermal-endodermal cell signaling	Any process that mediates the transfer of information from mesodermal cells to endodermal cells.	tmpzr1t_l9r_go_relaxed.owl	mesodermal-endodermal cell signalling							tb	2009-09-22T03:07:34Z					biological_process											owl:Class	
GO:0042548	biolink:NamedThing	regulation of photosynthesis, light reaction	Any process that modulates the frequency, rate or extent of the light-dependent reaction of photosynthesis.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0010109	biolink:NamedThing	regulation of photosynthesis	Any process that modulates the frequency, rate or extent of photosynthesis.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0043085	biolink:NamedThing	positive regulation of catalytic activity	Any process that activates or increases the activity of an enzyme.	tmpzr1t_l9r_go_relaxed.owl	activation of enzyme activity|upregulation of enzyme activity|up-regulation of enzyme activity|upregulation of metalloenzyme activity|up regulation of enzyme activity|activation of metalloenzyme activity|up-regulation of metalloenzyme activity|stimulation of enzyme activity|up regulation of metalloenzyme activity|positive regulation of enzyme activity|stimulation of metalloenzyme activity|positive regulation of metalloenzyme activity											GO:0048554		biological_process											owl:Class	
GO:1903795	biolink:NamedThing	regulation of inorganic anion transmembrane transport	Any process that modulates the frequency, rate or extent of inorganic anion transmembrane transport.	tmpzr1t_l9r_go_relaxed.owl	regulation of inorganic anion membrane transport|regulation of transmembrane inorganic anion transport							sl	2015-01-14T21:44:49Z					biological_process											owl:Class	
GO:0006432	biolink:NamedThing	phenylalanyl-tRNA aminoacylation	The process of coupling phenylalanine to phenylalanyl-tRNA, catalyzed by phenylalanyl-tRNA synthetase. The phenylalanyl-tRNA synthetase is a  class-II synthetase. However, unlike other class II enzymes, The activated amino acid is transferred to the 2'-OH group of a phenylalanine-accepting tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0036432	biolink:NamedThing	all-trans undecaprenol kinase activity	Catalysis of the reaction: ATP + undecaprenol + all-trans-undecaprenyl phosphate + ADP + H+.	tmpzr1t_l9r_go_relaxed.owl					RHEA:23752			bf	2013-09-16T14:21:04Z					molecular_function											owl:Class	
GO:0009038	biolink:NamedThing	undecaprenol kinase activity	Catalysis of the reaction: ATP + undecaprenol = ADP + undecaprenyl phosphate.	tmpzr1t_l9r_go_relaxed.owl	isoprenoid-alcohol kinase activity|isoprenoid alcohol kinase activity|C55-isoprenoid alcohol kinase activity|ATP:undecaprenol phosphotransferase activity|isoprenoid alcohol phosphokinase activity|isoprenoid alcohol kinase (phosphorylating)|C55-isoprenoid alcohol phosphokinase activity|polyisoprenol kinase activity|C55-isoprenyl alcohol phosphokinase activity				EC:2.7.1.66									molecular_function											owl:Class	
GO:0033274	biolink:NamedThing	response to vitamin B2	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin B2 stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to riboflavin													biological_process											owl:Class	
GO:0043793	biolink:NamedThing	beta-ribofuranosylaminobenzene 5'-phosphate synthase activity	Catalysis of the reaction: 4-aminobenzoate + 5-phospho-alpha-D-ribose 1-diphosphate = 4-(beta-D-ribofuranosyl)aminobenzene 5'-phosphate + CO2 + diphosphate.	tmpzr1t_l9r_go_relaxed.owl	beta-RFAP synthase activity				MetaCyc:RXN-8124									molecular_function											owl:Class	
GO:0072296	biolink:NamedThing	specification of metanephric loop of Henle identity	The process in which the loop of Henle of the metanephric nephron acquires its identity.	tmpzr1t_l9r_go_relaxed.owl	specification of metanephric intermediate tubule identity							mah	2010-04-09T04:08:05Z					biological_process											owl:Class	
GO:0072293	biolink:NamedThing	specification of metanephric nephron tubule identity	The process in which the tubules arranged along the proximal/distal axis of the metanephric nephron acquire their identity.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-04-09T03:58:10Z					biological_process											owl:Class	
GO:0010928	biolink:NamedThing	regulation of auxin mediated signaling pathway	Any process that modulates the rate, frequency or extent of auxin mediated signaling pathway. Auxin mediated signaling pathway is the series of molecular signals generated in response to detection of auxin.	tmpzr1t_l9r_go_relaxed.owl	regulation of auxin mediated signalling pathway													biological_process											owl:Class	
GO:0043219	biolink:NamedThing	lateral loop	Non-compact myelin located adjacent to the nodes of Ranvier in a myelin segment. These non-compact regions include cytoplasm from the cell responsible for synthesizing the myelin. Lateral loops are found in the paranodal region adjacent to the nodes of Ranvier, while Schmidt-Lantermann clefts are analogous structures found within the compact myelin internode.	tmpzr1t_l9r_go_relaxed.owl	Schwann cell paranodal termination|oligodendrocyte paranodal termination|paranodal loop				NIF_Subcellular:sao1067215520|NIF_Subcellular:sao1354781919									cellular_component											owl:Class	
GO:0046034	biolink:NamedThing	ATP metabolic process	The chemical reactions and pathways involving ATP, adenosine triphosphate, a universally important coenzyme and enzyme regulator.	tmpzr1t_l9r_go_relaxed.owl	ATP metabolism													biological_process											owl:Class	
GO:0098939	biolink:NamedThing	dendritic transport of mitochondrion	The directed movement of mitochondria along microtubules in nerve cell dendrites.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0034000	biolink:NamedThing	chondroitin-sulfate-ABC endolyase activity	Catalysis of the endolytic cleavage of beta-1,4-galactosaminic bonds between N-acetylgalactosamine and either D-glucuronic acid or L-iduronic acid to produce a mixture of Delta4-unsaturated oligosaccharides of different sizes that are ultimately degraded to Delta4-unsaturated tetra- and disaccharides.	tmpzr1t_l9r_go_relaxed.owl	ChS ABC lyase I activity|chondroitin sulfate ABC endoeliminase activity|chondroitin ABC eliminase activity|chondroitin sulfate ABC endolyase activity|ChS ABC lyase activity|chondroitinase activity|chondroitinase ABC activity|chondroitin sulfate ABC lyase activity				MetaCyc:4.2.2.20-RXN|EC:4.2.2.20									molecular_function											owl:Class	
GO:0052035	biolink:NamedThing	positive regulation by symbiont of host inflammatory response	Any process in which a symbiont activates, maintains or increases the frequency, rate or extent of the inflammatory response of the host organism; the inflammatory response is the immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	upregulation by symbiont of host inflammatory response|stimulation by symbiont of host inflammatory response|up-regulation by symbiont of host inflammatory response|positive regulation by organism of inflammatory response of other organism involved in symbiotic interaction|up regulation by symbiont of host inflammatory response|activation by symbiont of host inflammatory response											GO:0052259		biological_process											owl:Class	
GO:0044416	biolink:NamedThing	induction by symbiont of host defense response	The activation by an organism of the defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	upregulation by symbiont of host defense response|positive regulation by symbiont of host defense response|positive regulation by organism of defense response of other organism involved in symbiotic interaction|up regulation by symbiont of host defense response|up-regulation by symbiont of host defense response|induction by organism of defense response of other organism involved in symbiotic interaction|activation by symbiont of host defense response|stimulation by symbiont of host defense response|activation of host defense response											GO:0052251|GO:0052509|GO:0052510		biological_process											owl:Class	
GO:0051291	biolink:NamedThing	protein heterooligomerization	The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of component monomers that are not all identical. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer.	tmpzr1t_l9r_go_relaxed.owl	protein heterooligomer biosynthetic process|protein heterooligomer formation|protein heterooligomer biosynthesis|protein heterooligomer assembly													biological_process											owl:Class	
GO:0103014	biolink:NamedThing	beta-keto ester reductase activity	Catalysis of the reaction: ethyl-(2R)-methyl-(3S)-hydroxybutanoate + NADP = ethyl-2-methylacetoacetate + NADPH + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN0-1941									molecular_function											owl:Class	
GO:0008344	biolink:NamedThing	adult locomotory behavior	Locomotory behavior in a fully developed and mature organism.	tmpzr1t_l9r_go_relaxed.owl	adult locomotory behaviour					See also the biological process term 'locomotory behavior ; GO:0007626'.								biological_process											owl:Class	
GO:0045548	biolink:NamedThing	phenylalanine ammonia-lyase activity	Catalysis of the reaction: L-phenylalanine = NH(4)(+) + trans-cinnamate.	tmpzr1t_l9r_go_relaxed.owl	phe ammonia-lyase activity|phenylalanine ammonium-lyase activity|L-phenylalanine ammonia-lyase activity|PAL activity|phenylalanine deaminase activity				RHEA:21384|EC:4.3.1.25|EC:4.3.1.24									molecular_function											owl:Class	
GO:0050099	biolink:NamedThing	methylglutamate dehydrogenase activity	Catalysis of the reaction: N-methyl-L-glutamate + A + H(2)O = L-glutamate + AH(2) + formaldehyde.	tmpzr1t_l9r_go_relaxed.owl	N-methyl-L-glutamate:(acceptor) oxidoreductase (demethylating)|N-methyl-L-glutamate:acceptor oxidoreductase (demethylating)|N-methylglutamate dehydrogenase activity				EC:1.5.99.5|RHEA:22572|KEGG_REACTION:R00609|MetaCyc:METHYLGUTAMATE-DEHYDROGENASE-RXN									molecular_function											owl:Class	
GO:0006293	biolink:NamedThing	nucleotide-excision repair, preincision complex stabilization	The stabilization of the multiprotein complex involved in damage recognition, DNA helix unwinding, and endonucleolytic cleavage at the site of DNA damage as well as the unwound DNA. The stabilization of the protein-DNA complex ensures proper positioning of the preincision complex before the phosphodiester backbone of the damaged strand is cleaved 3' and 5' of the site of DNA damage.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0030964	biolink:NamedThing	NADH dehydrogenase complex	An integral membrane complex that possesses NADH oxidoreductase activity. The complex is one of the components of the electron transport chain. It catalyzes the transfer of a pair of electrons from NADH to a quinone.	tmpzr1t_l9r_go_relaxed.owl	NADH dehydrogenase complex (plastoquinone)|Complex I|NADH:plastoquinone reductase complex|NADH dehydrogenase complex (quinone)|plastid NADH dehydrogenase complex (plastoquinone)|NADH dehydrogenase complex (ubiquinone)				Wikipedia:NADH_dehydrogenase	Note that this term represents a location and not a function; the activity possessed by this complex is mentioned in the definition for the purpose of describing and distinguishing the complex. The function possessed by this complex is represented by the molecular function term 'NADH dehydrogenase (quinone) activity ; GO:0050136'.						GO:0031677|GO:0045280|GO:0031678|GO:0031675|GO:0030025|GO:0030966		cellular_component											owl:Class	
GO:0007494	biolink:NamedThing	midgut development	The process whose specific outcome is the progression of the midgut over time, from its formation to the mature structure. The midgut is the middle part of the alimentary canal from the stomach, or entrance of the bile duct, to, or including, the large intestine.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0018531	biolink:NamedThing	(S)-6-hydroxynicotine oxidase activity	Catalysis of the reaction: (S)-6-hydroxynicotine + H(2)O + O(2) = 6-hydroxypseudooxynicotine + H(2)O(2).	tmpzr1t_l9r_go_relaxed.owl	6-hydroxy-L-nicotine oxidase activity|L-6-hydroxynicotine oxidase activity|6-hydroxy-L-nicotine:oxygen oxidoreductase activity|(S)-6-hydroxynicotine:oxygen oxidoreductase activity				RHEA:11880|UM-BBD_reactionID:r0478|MetaCyc:S-6-HYDROXYNICOTINE-OXIDASE-RXN|EC:1.5.3.5|KEGG_REACTION:R03202									molecular_function											owl:Class	
GO:0019116	biolink:NamedThing	hydroxy-nicotine oxidase activity	Catalysis of the reaction: 6-hydroxynicotine + H2O + O2 = 1-(6-hydroxypyrid-3-yl)-4-(methylamino)butan-1-one + hydrogen peroxide.	tmpzr1t_l9r_go_relaxed.owl					EC:1.5.3.6									molecular_function											owl:Class	
GO:1900686	biolink:NamedThing	regulation of gerfelin biosynthetic process	Any process that modulates the frequency, rate or extent of gerfelin biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of gerfelin synthesis|regulation of gerfelin biosynthesis|regulation of gerfelin anabolism|regulation of gerfelin formation							di	2012-05-22T04:49:44Z					biological_process											owl:Class	
GO:1902545	biolink:NamedThing	negative regulation of DNA N-glycosylase activity	Any process that stops, prevents or reduces the frequency, rate or extent of DNA N-glycosylase activity.	tmpzr1t_l9r_go_relaxed.owl	down regulation of DNA N-glycosylase activity|down-regulation of DNA glycosylase activity|inhibition of DNA N-glycosylase activity|inhibition of endonuclease VIII activity|inhibition of DNA glycosylase activity|down regulation of endonuclease VIII activity|negative regulation of DNA glycosylase activity|down-regulation of endonuclease VIII activity|downregulation of endonuclease VIII activity|downregulation of DNA N-glycosylase activity|down regulation of DNA glycosylase activity|downregulation of DNA glycosylase activity|negative regulation of endonuclease VIII activity|down-regulation of DNA N-glycosylase activity							rph	2013-12-04T14:18:03Z					biological_process											owl:Class	
GO:0002860	biolink:NamedThing	positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target	Any process that activates or increases the frequency, rate, or extent of natural killer cell mediated cytotoxicity directed against tumor cell target.	tmpzr1t_l9r_go_relaxed.owl	stimulation of natural killer cell mediated cytotoxicity directed against tumor cell target|up-regulation of natural killer cell mediated cytotoxicity directed against tumor cell target|up regulation of natural killer cell mediated cytotoxicity directed against tumor cell target|activation of natural killer cell mediated cytotoxicity directed against tumor cell target|upregulation of natural killer cell mediated cytotoxicity directed against tumor cell target													biological_process											owl:Class	
GO:0033089	biolink:NamedThing	positive regulation of T cell differentiation in thymus	Any process that activates or increases the frequency, rate or extent of T cell differentiation in the thymus.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of thymocyte cell differentiation|positive regulation of thymic T cell differentiation|positive regulation of T cell development in thymus|positive regulation of thymocyte differentiation					Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.								biological_process											owl:Class	
GO:0046950	biolink:NamedThing	cellular ketone body metabolic process	The chemical reactions and pathways involving ketone bodies, any one of the three substances: acetoacetate, D-3-hydroxybutyrate (beta-hydroxybutyrate) or acetone, as carried out by individual cells. Although 3-hydroxybutyrate is not a ketone, it is classed as a ketone body because it exists in an equilibrium with acetoacetate. Ketone bodies may accumulate in excessive amounts in the body in starvation, diabetes mellitus or in other defects of carbohydrate metabolism.	tmpzr1t_l9r_go_relaxed.owl	cellular ketone body metabolism													biological_process											owl:Class	
GO:0008834	biolink:NamedThing	di-trans,poly-cis-decaprenylcistransferase activity	Catalysis of the reaction: di-trans-poly-cis-decaprenyl diphosphate + isopentenyl diphosphate = diphosphate + di-trans-poly-cis-undecaprenyl diphosphate.	tmpzr1t_l9r_go_relaxed.owl	di-trans,poly-cis-decaprenyl-diphosphate:isopentenyl-diphosphate undecaprenylcistransferase activity|undecaprenyl diphosphate synthase activity|di-trans,poly-cis-undecaprenyl-diphosphate synthase activity|UPP synthetase activity|undecaprenyl pyrophosphate synthetase activity|undecaprenyl diphosphate synthetase activity|undecaprenyl pyrophosphate synthase activity|undecaprenyl-diphosphate synthase activity|bactoprenyl-diphosphate synthase activity				RHEA:27551|EC:2.5.1.31|MetaCyc:RXN-8999									molecular_function											owl:Class	
GO:1900754	biolink:NamedThing	4-hydroxyphenylacetate transport	The directed movement of a 4-hydroxyphenylacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	2-(4-hydroxyphenyl)ethanoate transport|4-hydroxybenzeneacetate transport|(p-hydroxyphenyl)acetate transport|(4-hydroxyphenyl)acetate transport							jl	2012-05-29T02:59:02Z					biological_process											owl:Class	
GO:0031350	biolink:NamedThing	intrinsic component of plastid membrane	The component of the plastid membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.	tmpzr1t_l9r_go_relaxed.owl	intrinsic to plastid membrane													cellular_component											owl:Class	
GO:0034152	biolink:NamedThing	negative regulation of toll-like receptor 6 signaling pathway	Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 6 signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of toll-like receptor 6 signalling pathway|negative regulation of TLR6 signaling pathway													biological_process											owl:Class	
GO:0034151	biolink:NamedThing	regulation of toll-like receptor 6 signaling pathway	Any process that modulates the frequency, rate, or extent of toll-like receptor 6 signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	regulation of toll-like receptor 6 signalling pathway|regulation of TLR6 signaling pathway													biological_process											owl:Class	
GO:0090356	biolink:NamedThing	negative regulation of auxin metabolic process	Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving auxins, plant hormones that regulate aspects of plant growth.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of auxin metabolism							tb	2010-06-29T01:51:18Z					biological_process											owl:Class	
GO:2000690	biolink:NamedThing	regulation of cardiac muscle cell myoblast differentiation	Any process that modulates the frequency, rate or extent of cardiac muscle cell myoblast differentiation.	tmpzr1t_l9r_go_relaxed.owl	regulation of myocardial precursor cell differentiation|regulation of cardiac myoblast differentiation							yaf	2011-05-25T09:08:01Z					biological_process											owl:Class	
GO:0034229	biolink:NamedThing	ethanolamine transport	The directed movement of ethanolamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Ethanolamine (2-aminoethanol, monoethanolamine) is an amino alcohol that occurs widely in living organisms as a constituent of certain types of phospholipids, such as phosphatidylethanolamine.	tmpzr1t_l9r_go_relaxed.owl	monoethanolamine transport|2-aminoethanol transport													biological_process											owl:Class	
GO:0003308	biolink:NamedThing	negative regulation of Wnt signaling pathway involved in heart development	Any process that decreases the rate, frequency, or extent of the series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of the target cell, resulting a change in cell state that contributes to the progression of the heart over time.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of Wnt-activated signaling pathway involved in heart development|negative regulation of Wnt receptor signalling pathway involved in heart development|negative regulation of Wnt receptor signaling pathway involved in heart development							dph	2009-10-22T12:36:11Z					biological_process											owl:Class	
GO:0047900	biolink:NamedThing	formate kinase activity	Catalysis of the reaction: ATP + formate = ADP + formyl phosphate + H(+).	tmpzr1t_l9r_go_relaxed.owl	ATP:formate phosphotransferase activity				MetaCyc:FORMATE-KINASE-RXN|KEGG_REACTION:R00518|EC:2.7.2.6|RHEA:16009									molecular_function											owl:Class	
GO:0140434	biolink:NamedThing	positive regulation of protein localization to meiotic spindle pole body	Any process that increases the frequency, rate or extent of protein localization to a meiotic spindle pole body.	tmpzr1t_l9r_go_relaxed.owl								pg	2020-02-24T13:27:01Z					biological_process											owl:Class	
GO:0050061	biolink:NamedThing	long-chain-aldehyde dehydrogenase activity	Catalysis of the reaction: a long-chain aldehyde + NAD+ = a long-chain carboxylate + NADH + H+. A long-chain aldehyde is one with more than 12 carbons.	tmpzr1t_l9r_go_relaxed.owl	fatty aldehyde:NAD+ oxidoreductase activity|long-chain aliphatic aldehyde dehydrogenase activity|long-chain fatty aldehyde dehydrogenase activity|long-chain-aldehyde:NAD+ oxidoreductase activity				RHEA:10652|EC:1.2.1.48|UM-BBD_reactionID:r1404|MetaCyc:LONG-CHAIN-ALDEHYDE-DEHYDROGENASE-RXN									molecular_function											owl:Class	
GO:0008098	biolink:NamedThing	5S rRNA primary transcript binding	Binding to an unprocessed 5S ribosomal RNA transcript.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0008097	biolink:NamedThing	5S rRNA binding	Binding to a 5S ribosomal RNA, the smallest RNA constituent of a ribosome.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0140026	biolink:NamedThing	contractile vacuole dissociation from plasma membrane	The dissociation of the contractile vacuole after discharge, from the plasma membrane. This interaction is mediated by detethering factors that initiate the process of tubulation and fragmentation of the empty contractile vacuole bladder, which is then reincorporated into the CV network.	tmpzr1t_l9r_go_relaxed.owl	contractile vacuole detethering from plasma membrane	https://github.com/geneontology/go-ontology/issues/13407						pg	2017-05-02T10:16:12Z					biological_process											owl:Class	
GO:0021906	biolink:NamedThing	hindbrain-spinal cord boundary formation	The process whose specific outcome is the formation of the hindbrain-spinal cord boundary.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1990871	biolink:NamedThing	Vma12-Vma22 assembly complex	A protein complex that is involved in the assembly of the V-ATPase complex. In the budding yeast Saccharomyces cerevisiae, this complex consists of Vma12p and Vma22p.	tmpzr1t_l9r_go_relaxed.owl								rb	2015-09-28T19:03:28Z					cellular_component											owl:Class	
GO:0021737	biolink:NamedThing	emboliform nucleus development	The process whose specific outcome is the progression of the emboliform nucleus over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0048438	biolink:NamedThing	floral whorl development	The process whose specific outcome is the progression of a floral whorl over time, from its formation to the mature structure. A floral whorl is a circular arrangement of parts of a flower arising from a stem of a plant.	tmpzr1t_l9r_go_relaxed.owl	collective phyllome structure development					Consider instead annotating to one of the more specific child terms, or to 'floral organ development ; GO:0048438' or one of its child terms.						GO:0048413		biological_process											owl:Class	
GO:0045008	biolink:NamedThing	depyrimidination	The disruption of the bond between the sugar in the backbone and the C or T base, causing the base to be removed and leaving a depyrimidinated sugar.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0002616	biolink:NamedThing	regulation of macrophage antigen processing and presentation	Any process that modulates the frequency, rate, or extent of macrophage antigen processing and presentation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0070279	biolink:NamedThing	vitamin B6 binding	Binding to a vitamin B6 compound: pyridoxal, pyridoxamine, pyridoxine, or the active form, pyridoxal phosphate.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0019842	biolink:NamedThing	vitamin binding	Binding to a vitamin, one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0010124	biolink:NamedThing	phenylacetate catabolic process	The chemical reactions and pathways resulting in the breakdown of phenylacetate.	tmpzr1t_l9r_go_relaxed.owl	phenylacetate breakdown|phenylacetate catabolism|phenylacetate degradation				MetaCyc:PWY0-321									biological_process											owl:Class	
GO:0034589	biolink:NamedThing	hydroxyproline transport	The directed movement of hydroxyproline into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	4-hydroxyproline transport|L-hydroxyproline transport													biological_process											owl:Class	
GO:1902486	biolink:NamedThing	protein localization to growing cell tip	A process in which a protein is transported to, or maintained in, a location within a growing cell tip.	tmpzr1t_l9r_go_relaxed.owl	protein localization in growing cell tip|protein localisation in growing cell tip|protein localisation to growing cell tip							mah	2013-11-12T16:38:13Z					biological_process											owl:Class	
GO:1904492	biolink:NamedThing	Ac-Asp-Glu binding	Binding to Ac-Asp-Glu.	tmpzr1t_l9r_go_relaxed.owl								hal	2015-07-20T10:32:49Z					molecular_function											owl:Class	
GO:0018833	biolink:NamedThing	DDT-dehydrochlorinase activity	Catalysis of the reaction: 1,1,1-trichloro-2,2-bis(4-chlorophenyl)ethane = 1,1-dichloro-2,2-bis(4-chlorophenyl)ethylene + chloride + H(+).	tmpzr1t_l9r_go_relaxed.owl	DDT-as|DDTase activity|DDT-ase activity|DDT dehydrochlorinase activity|1,1,1-trichloro-2,2-bis(4-chlorophenyl)ethane chloride-lyase activity|1,1,1-trichloro-2,2-bis(4-chlorophenyl)ethane chloride-lyase [1,1-dichloro-2,2-bis(4-chlorophenyl)ethylene-forming]				MetaCyc:DDT-DEHYDROCHLORINASE-RXN|KEGG_REACTION:R04522|UM-BBD_reactionID:r0439|RHEA:19217|EC:4.5.1.1									molecular_function											owl:Class	
GO:0016848	biolink:NamedThing	carbon-halide lyase activity	Catalysis of the breakage of a bond between carbon and any halogen atom.	tmpzr1t_l9r_go_relaxed.owl					EC:4.5.-.-									molecular_function											owl:Class	
GO:1900837	biolink:NamedThing	regulation of fumigaclavine C biosynthetic process	Any process that modulates the frequency, rate or extent of fumigaclavine C biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of fumigaclavine C anabolism|regulation of fumigaclavine C synthesis|regulation of fumigaclavine C formation|regulation of fumigaclavine C biosynthesis							di	2012-06-07T09:36:22Z					biological_process											owl:Class	
GO:0098502	biolink:NamedThing	DNA dephosphorylation	The process of removing one or more phosphate groups from a DNA molecule.	tmpzr1t_l9r_go_relaxed.owl								dos	2013-09-18T14:50:16Z					biological_process											owl:Class	
GO:0039628	biolink:NamedThing	T=169 icosahedral viral capsid	The protein coat that surrounds the infective nucleic acid in some virus particles where the subunits (capsomeres) are arranged to form an icosahedron with T=169 symmetry. T=169 icosahedral capsid is composed of 12 pentameric and 1680 hexameric capsomeres for a total of 10140 capsid proteins.	tmpzr1t_l9r_go_relaxed.owl	T=169 icosahedral capsid							bf	2012-08-03T16:27:55Z					cellular_component											owl:Class	
GO:0014706	biolink:NamedThing	striated muscle tissue development	The process whose specific outcome is the progression of a striated muscle over time, from its formation to the mature structure. Striated muscle contain fibers that are divided by transverse bands into striations, and cardiac and skeletal muscle are types of striated muscle. Skeletal muscle myoblasts fuse to form myotubes and eventually multinucleated muscle fibers. The fusion of cardiac cells is very rare and can only form binucleate cells.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0120190	biolink:NamedThing	negative regulation of bile acid secretion	Any process that stops, prevents or reduces the frequency, rate or extent of the controlled release of bile acid from a cell or a tissue.	tmpzr1t_l9r_go_relaxed.owl								krc	2018-07-16T22:38:34Z					biological_process											owl:Class	
GO:0021540	biolink:NamedThing	corpus callosum morphogenesis	The process in which the anatomical structures of the corpus callosum are generated and organized. The corpus callosum is a thick bundle of nerve fibers comprising a commissural plate connecting the two cerebral hemispheres. It consists of contralateral axon projections that provides communications between the right and left cerebral hemispheres.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1901525	biolink:NamedThing	negative regulation of mitophagy	Any process that stops, prevents or reduces the frequency, rate or extent of mitophagy.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of macromitophagy|down regulation of macromitophagy|down-regulation of macromitophagy|downregulation of macromitophagy|inhibition of macromitophagy							krc	2012-10-22T16:56:49Z					biological_process											owl:Class	
GO:1901524	biolink:NamedThing	regulation of mitophagy	Any process that modulates the frequency, rate or extent of macromitophagy.	tmpzr1t_l9r_go_relaxed.owl	regulation of macromitophagy							krc	2012-10-22T16:56:45Z					biological_process											owl:Class	
GO:1902370	biolink:NamedThing	regulation of tRNA catabolic process	Any process that modulates the frequency, rate or extent of tRNA catabolic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of tRNA degradation|regulation of tRNA catabolism|regulation of tRNA breakdown							bf	2013-08-22T15:08:12Z					biological_process											owl:Class	
GO:1903326	biolink:NamedThing	regulation of tRNA metabolic process	Any process that modulates the frequency, rate or extent of tRNA metabolic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of tRNA metabolism							vw	2014-08-18T13:08:50Z					biological_process											owl:Class	
GO:0048683	biolink:NamedThing	regulation of collateral sprouting of intact axon in response to injury	Any process that modulates the frequency, rate or extent of collateral sprouting of an intact axon as a result of injury to an axon.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0015532	biolink:NamedThing	alpha-ketoglutarate:proton symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: alpha-ketoglutarate(out) + H+(out) = alpha-ketoglutarate(in) + H+(in).	tmpzr1t_l9r_go_relaxed.owl	2-oxoglutarate:hydrogen symporter activity|alpha-ketoglutarate:hydrogen symporter activity|2-oxoglutarate:proton symporter activity													molecular_function											owl:Class	
GO:0009638	biolink:NamedThing	phototropism	The movement of an organism, or part of an organism, in response to a light stimulus, usually toward or away from it.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Phototropism									biological_process											owl:Class	
GO:0009606	biolink:NamedThing	tropism	The movement of an organism, or part of an organism, in response to an external source of stimulus, usually toward or away from it.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Tropism									biological_process											owl:Class	
GO:0061440	biolink:NamedThing	kidney vasculature development	The process whose specific outcome is the progression of the vasculature of the kidney over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl								dph	2012-03-08T12:39:09Z					biological_process											owl:Class	
GO:0061437	biolink:NamedThing	renal system vasculature development	The process whose specific outcome is the progression of vasculature of the renal system over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl								dph	2012-03-08T12:16:24Z					biological_process											owl:Class	
GO:0070088	biolink:NamedThing	PHA granule	An inclusion body located in the cytoplasm that consists of polyhydroxyalkanoate (PHA) molecules and associated proteins, surrounded by a phospholipid monolayer; the proteins include PHA synthase, PHA depolymerase and 3HB-oligomer hydroxylase, phasins (PhaPs), which are thought to be the major structural proteins of the membrane surrounding the inclusion, and the regulator of phasin expression PhaR.	tmpzr1t_l9r_go_relaxed.owl	PHB granule|polyhydroxyalkanoate granule													cellular_component											owl:Class	
GO:0098810	biolink:NamedThing	neurotransmitter reuptake	The directed movement of neurotransmitter molecules from the extrasynaptic space into the presynaptic cytosol.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0017108	biolink:NamedThing	5'-flap endonuclease activity	Catalysis of the cleavage of a 5' flap structure in DNA, but not other DNA structures; processes the 5' ends of Okazaki fragments in lagging strand DNA synthesis.	tmpzr1t_l9r_go_relaxed.owl	5' flap endonuclease activity				Reactome:R-HSA-174446|Reactome:R-HSA-5687664|Reactome:R-HSA-69152|Reactome:R-HSA-110363|Reactome:R-HSA-5651782|Reactome:R-HSA-174441									molecular_function											owl:Class	
GO:0048256	biolink:NamedThing	flap endonuclease activity	Catalysis of the cleavage of a flap structure in DNA, but not other DNA structures; processes the ends of Okazaki fragments in lagging strand DNA synthesis.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1905620	biolink:NamedThing	negative regulation of alpha-(1->3)-fucosyltransferase activity	Any process that stops, prevents or reduces the frequency, rate or extent of alpha-(1->3)-fucosyltransferase activity.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of alpha-1,3-fucosyltransferase activity|negative regulation of alpha-(1,3)-fucosyltransferase activity|downregulation of alpha-1,3-fucosyltransferase activity|downregulation of alpha(1,3)-fucosyltransferase activity|down regulation of alpha-(1->3)-fucosyltransferase activity|down regulation of alpha(1,3)-fucosyltransferase activity|inhibition of alpha-(1,3)-fucosyltransferase activity|down-regulation of alpha-(1->3)-fucosyltransferase activity|down-regulation of alpha(1,3)-fucosyltransferase activity|down-regulation of alpha-1,3-fucosyltransferase activity|down regulation of alpha-(1,3)-fucosyltransferase activity|inhibition of alpha-(1->3)-fucosyltransferase activity|inhibition of alpha-1,3-fucosyltransferase activity|down regulation of alpha-1,3-fucosyltransferase activity|downregulation of alpha-(1->3)-fucosyltransferase activity|inhibition of alpha(1,3)-fucosyltransferase activity|down-regulation of alpha-(1,3)-fucosyltransferase activity|downregulation of alpha-(1,3)-fucosyltransferase activity|negative regulation of alpha(1,3)-fucosyltransferase activity							rz	2016-10-28T14:39:45Z					biological_process											owl:Class	
GO:2000958	biolink:NamedThing	negative regulation of cyclodextrin catabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of cyclodextrin catabolic process.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of cyclodextrin catabolism							tt	2011-08-01T02:24:02Z					biological_process											owl:Class	
GO:0036109	biolink:NamedThing	alpha-linolenic acid metabolic process	The chemical reactions and pathways involving alpha-linolenic acid, an unsaturated omega-6 fatty acid that has the molecular formula C18H32O2.	tmpzr1t_l9r_go_relaxed.owl	alpha-linolenic acid metabolism|ALA metabolism				Wikipedia:Linoleic_acid			bf	2012-02-15T10:16:42Z					biological_process											owl:Class	
GO:0001676	biolink:NamedThing	long-chain fatty acid metabolic process	The chemical reactions and pathways involving long-chain fatty acids, A long-chain fatty acid is a fatty acid with a chain length between C13 and C22.	tmpzr1t_l9r_go_relaxed.owl	long-chain fatty acid metabolism													biological_process											owl:Class	
GO:0032619	biolink:NamedThing	interleukin-16 production	The appearance of interleukin-16 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	tmpzr1t_l9r_go_relaxed.owl	interleukin-16 biosynthetic process|interleukin-16 secretion|LCF production|pro-interleukin-16 production|IL-16 production											GO:0042234|GO:0072614		biological_process											owl:Class	
GO:0009449	biolink:NamedThing	gamma-aminobutyric acid biosynthetic process	The chemical reactions and pathways resulting in the formation of gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms.	tmpzr1t_l9r_go_relaxed.owl	4-aminobutanoate biosynthesis|GABA biosynthesis|gamma-aminobutyric acid biosynthesis|4-aminobutyrate biosynthesis|gamma-aminobutyric acid synthesis|4-aminobutyrate biosynthetic process|gamma-aminobutyric acid formation|GABA biosynthetic process|4-aminobutanoate biosynthetic process|gamma-aminobutyric acid anabolism					See also the biological process term 'neurotransmitter biosynthetic process ; GO:0042136'.								biological_process											owl:Class	
GO:0009448	biolink:NamedThing	gamma-aminobutyric acid metabolic process	The chemical reactions and pathways involving gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms.	tmpzr1t_l9r_go_relaxed.owl	GABA metabolic process|gamma-aminobutyric acid metabolism|4-aminobutyrate metabolism|4-aminobutanoate metabolism|GABA metabolism|4-aminobutyrate metabolic process|4-aminobutanoate metabolic process					See also the biological process term 'neurotransmitter metabolic process ; GO:0042133'.								biological_process											owl:Class	
GO:0000144	biolink:NamedThing	cellular bud neck septin ring	A ring-shaped structure that forms at the site of cytokinesis in the bud neck of a budding cell; composed of members of the conserved family of filament forming proteins called septins as well as septin-associated proteins. In S. cerevisiae, this structure forms at the time of bud emergence and the septins show a high rate of exchange.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0090464	biolink:NamedThing	histidine homeostasis	Any process involved in the maintenance of an internal steady state of histidine within an organism or cell.	tmpzr1t_l9r_go_relaxed.owl								tb	2012-09-24T14:22:02Z					biological_process											owl:Class	
GO:0060604	biolink:NamedThing	mammary gland duct cavitation	Creation of the central hole of the mammary gland duct by the hollowing out of a solid rod.	tmpzr1t_l9r_go_relaxed.owl	milk duct cavitation							dph	2009-05-15T09:34:07Z					biological_process											owl:Class	
GO:0006623	biolink:NamedThing	protein targeting to vacuole	The process of directing proteins towards the vacuole, usually using signals contained within the protein.	tmpzr1t_l9r_go_relaxed.owl	protein vacuolar targeting|protein-vacuolar targeting|vacuolar protein sorting|protein-vacuole targeting													biological_process											owl:Class	
GO:0042437	biolink:NamedThing	indoleacetic acid catabolic process	The chemical reactions and pathways resulting in the breakdown of indole-3-acetic acid, a compound which functions as a growth regulator in plants.	tmpzr1t_l9r_go_relaxed.owl	IAA catabolic process|indole acetic acid catabolism|indole acetic acid catabolic process|indoleacetic acid degradation|indoleacetic acid catabolism|indoleacetic acid breakdown													biological_process											owl:Class	
GO:1902754	biolink:NamedThing	positive regulation of renal amino acid absorption	Any process that activates or increases the frequency, rate or extent of renal amino acid absorption.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of renal amino acid absorption|up regulation of renal amino acid absorption|upregulation of renal amino acid absorption|activation of renal amino acid absorption							hjd	2014-03-05T15:44:07Z					biological_process											owl:Class	
GO:1903018	biolink:NamedThing	regulation of glycoprotein metabolic process	Any process that modulates the frequency, rate or extent of glycoprotein metabolic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of glycoprotein metabolism					human serum amyloid P component (SAP) P02743 inhibits viral neuraminidase, NA (exo-alpha-sialidase activity) and thus the metabolism of glycoproteins, demonstrated in Figure 4A PMID:23544079, (IDA), the negative regulation term would be applied to this protein		rl	2014-05-14T18:44:19Z					biological_process											owl:Class	
GO:0140632	biolink:NamedThing	inflammasome complex assembly	The aggregation, arrangement and bonding together of a set of components to form an inflammasome complex.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/21092						pg	2021-04-09T11:11:41Z					biological_process											owl:Class	
GO:0000126	biolink:NamedThing	transcription factor TFIIIB complex	A transcription factor complex that is involved in regulating transcription from RNA polymerase III (Pol III) promoters. TFIIIB contains the TATA-binding protein (TBP) and two Pol III-specific proteins, B'' and BRF.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0033574	biolink:NamedThing	response to testosterone	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a testosterone stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to testosterone stimulus													biological_process											owl:Class	
GO:1905552	biolink:NamedThing	positive regulation of protein localization to endoplasmic reticulum	Any process that activates or increases the frequency, rate or extent of protein localization to endoplasmic reticulum.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of protein localization to endoplasmic reticulum|up-regulation of protein localization in ER|positive regulation of protein localisation in endoplasmic reticulum|up-regulation of protein localisation in endoplasmic reticulum|activation of protein localization in ER|activation of protein localization to endoplasmic reticulum|upregulation of protein localization to endoplasmic reticulum|up regulation of protein localization in ER|up-regulation of protein localization in endoplasmic reticulum|positive regulation of protein localization in ER|up regulation of protein localization in endoplasmic reticulum|upregulation of protein localization in ER|upregulation of protein localization in endoplasmic reticulum|positive regulation of protein localization in endoplasmic reticulum|up regulation of protein localization to endoplasmic reticulum|up regulation of protein localisation in endoplasmic reticulum|activation of protein localisation in endoplasmic reticulum|upregulation of protein localisation in endoplasmic reticulum|activation of protein localization in endoplasmic reticulum							rz	2016-10-12T11:37:16Z					biological_process											owl:Class	
GO:0102850	biolink:NamedThing	1-18:1-2-16:0-phosphatidylglycerol omega-6 desaturase activity	Catalysis of the reaction: 1-[(9Z)-octadec-9-enoyl]-2-hexadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol)(1-) + O2 + a reduced electron acceptor <=> 1-18:2-2-16:0-phosphatidylglycerol + 2 H2O + an oxidized electron acceptor.	tmpzr1t_l9r_go_relaxed.owl					RHEA:46376|EC:1.14.19.23|MetaCyc:RXN-8316									molecular_function											owl:Class	
GO:0046877	biolink:NamedThing	regulation of saliva secretion	Any process that modulates the frequency, rate or extent of the regulated release of saliva from a cell or a tissue.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0061503	biolink:NamedThing	tRNA threonylcarbamoyladenosine dehydratase	Catalysis of the ATP-dependent dehydration of t6A to form cyclic t6A.	tmpzr1t_l9r_go_relaxed.owl								dph	2013-01-22T14:22:14Z					molecular_function											owl:Class	
GO:0014806	biolink:NamedThing	smooth muscle hyperplasia	A process, occurring in smooth muscle, in which there is an increase in cell number by cell division, often leading to an increase in the size of an organ.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0106105	biolink:NamedThing	Ala-tRNA(Thr) hydrolase activity	Catalysis of the hydrolysis of misacylated ala-tRNA(thr).	tmpzr1t_l9r_go_relaxed.owl	L-alanyl-tRNA(Thr) deacylase							hjd	2018-03-14T22:03:29Z					molecular_function											owl:Class	
GO:0070352	biolink:NamedThing	positive regulation of white fat cell proliferation	Any process that activates or increases the rate or extent of white fat cell proliferation.	tmpzr1t_l9r_go_relaxed.owl	up regulation of white fat cell proliferation|positive regulation of white adipocyte proliferation|positive regulation of white adipose cell proliferation|activation of white fat cell proliferation|upregulation of white fat cell proliferation|up-regulation of white fat cell proliferation|stimulation of white fat cell proliferation													biological_process											owl:Class	
GO:0097163	biolink:NamedThing	sulfur carrier activity	Covalently binding to sulfur and delivering it to an acceptor molecule.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/14455						pr	2011-09-27T10:15:41Z					molecular_function											owl:Class	
GO:0009787	biolink:NamedThing	regulation of abscisic acid-activated signaling pathway	Any process that modulates the frequency, rate or extent of abscisic acid (ABA) signaling.	tmpzr1t_l9r_go_relaxed.owl	regulation of abscisic acid mediated signalling|regulation of abscisic acid mediated signaling pathway													biological_process											owl:Class	
GO:0046984	biolink:NamedThing	regulation of hemoglobin biosynthetic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hemoglobin, an oxygen carrying, conjugated protein containing four heme groups and globin.	tmpzr1t_l9r_go_relaxed.owl	regulation of haemoglobin biosynthesis|regulation of hemoglobin biosynthesis|regulation of hemoglobin synthesis|regulation of hemoglobin formation|regulation of hemoglobin anabolism|regulation of haemoglobin biosynthetic process													biological_process											owl:Class	
GO:2000112	biolink:NamedThing	regulation of cellular macromolecule biosynthetic process	Any process that modulates the frequency, rate or extent of cellular macromolecule biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of cellular macromolecule biosynthesis|regulation of cellular biopolymer biosynthetic process|regulation of cellular macromolecule anabolism|regulation of cellular macromolecule synthesis|regulation of cellular macromolecule formation							tb	2010-09-15T08:55:45Z					biological_process											owl:Class	
GO:0051424	biolink:NamedThing	corticotropin-releasing hormone binding	Binding to corticotropin-releasing hormone, a polypeptide hormone involved in the stress response. It is released by the hypothalamus and stimulates the release of corticotropin by the anterior pituitary gland.	tmpzr1t_l9r_go_relaxed.owl	corticotropin-releasing factor binding|CRH binding|CRF binding|corticoliberin binding											GO:0017047		molecular_function											owl:Class	
GO:0016278	biolink:NamedThing	lysine N-methyltransferase activity	Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to the epsilon-amino group of a lysine residue.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-6805740|Reactome:R-HSA-6805730|Reactome:R-HSA-6805755|Reactome:R-HSA-3222237									molecular_function											owl:Class	
GO:0035570	biolink:NamedThing	N-terminal peptidyl-serine methylation	The methylation of the N-terminal serine of proteins.	tmpzr1t_l9r_go_relaxed.owl								bf	2010-08-06T01:58:11Z					biological_process											owl:Class	
GO:1901440	biolink:NamedThing	poly(hydroxyalkanoate) metabolic process	The chemical reactions and pathways involving poly(hydroxyalkanoate).	tmpzr1t_l9r_go_relaxed.owl	poly(hydroxyalkanoate) metabolism							tt	2012-10-02T01:47:26Z					biological_process											owl:Class	
GO:1901493	biolink:NamedThing	response to decalin	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a decalin stimulus.	tmpzr1t_l9r_go_relaxed.owl								tt	2012-10-16T13:41:09Z					biological_process											owl:Class	
GO:0042657	biolink:NamedThing	MHC class II protein binding, via lateral surface	Binding to the lateral surface of major histocompatibility complex class II molecules.	tmpzr1t_l9r_go_relaxed.owl	major histocompatibility complex class II protein binding, via lateral surface													molecular_function											owl:Class	
GO:0042289	biolink:NamedThing	MHC class II protein binding	Binding to a major histocompatibility complex class II molecule; a set of molecules displayed on cell surfaces that are responsible for lymphocyte recognition and antigen presentation.	tmpzr1t_l9r_go_relaxed.owl	major histocompatibility complex class II binding|major histocompatibility complex class II ligand					Note that this term does not include binding to the antigen peptide bound to the MHC protein. Consider also annotating to the molecular function term 'peptide antigen binding ; GO:0042605' or one of its children.								molecular_function											owl:Class	
GO:1990451	biolink:NamedThing	cellular stress response to acidic pH	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in the homeostasis of organismal or cellular pH (with pH < 7). pH is a measure of the acidity or basicity of an aqueous solution.	tmpzr1t_l9r_go_relaxed.owl	cellular stress response to acidity					An example of this is NOX1 in human (Q9Y5S8) in PMID:10615049.		jl	2014-08-06T14:06:58Z					biological_process											owl:Class	
GO:1990135	biolink:NamedThing	flavonoid sulfotransferase activity	Catalysis of the reaction: a flavonoid + 3'-phosphoadenosine-5'-phosphosulfate = sulfated flavonoid + adenosine-3',5'-diphosphate. This reaction is the transfer of a sulfate group to the hydroxyl group of a flavonoid acceptor, producing the sulfated flavonoid derivative.	tmpzr1t_l9r_go_relaxed.owl								tb	2013-06-28T22:07:27Z					molecular_function											owl:Class	
GO:0050271	biolink:NamedThing	S-alkylcysteine lyase activity	Catalysis of the reaction: an S-alkyl-L-cysteine + H2O = an alkyl thiol + NH3 + pyruvate.	tmpzr1t_l9r_go_relaxed.owl	alkyl cysteine lyase activity|S-alkyl-L-cysteinase activity|alkylcysteine lyase activity|S-alkyl-L-cysteine lyase activity|S-alkyl-L-cysteine sulfoxide lyase activity|S-alkyl-L-cysteine alkylthiol-lyase (deaminating) activity|S-alkyl-L-cysteine alkylthiol-lyase (deaminating; pyruvate-forming)|S-alkylcysteinase activity				RHEA:22424|MetaCyc:S-ALKYLCYSTEINE-LYASE-RXN|EC:4.4.1.6									molecular_function											owl:Class	
GO:0034407	biolink:NamedThing	cell wall (1->3)-beta-D-glucan metabolic process	The chemical reactions and pathways involving (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds, found in the walls of cells.	tmpzr1t_l9r_go_relaxed.owl	cell wall 1,3-beta-D-glucan metabolic process|cell wall 1,3-beta-glucan metabolism|cell wall beta-1,3 glucan metabolic process|cell wall 1,3-beta-glucan metabolic process|cell wall beta-1,3 glucan metabolism													biological_process											owl:Class	
GO:0035134	biolink:NamedThing	post-embryonic dorsal fin morphogenesis	The process, occurring after embryonic development, by which the anatomical structures of the dorsal fin are generated and organized. A dorsal fin is an unpaired medial fin on the dorsal aspect of a fish that provides lateral stability while swimming. Generally fish have one or two dorsal fins.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0035142	biolink:NamedThing	dorsal fin morphogenesis	The process in which the anatomical structures of the dorsal fin are generated and organized. A dorsal fin is an unpaired medial fin on the dorsal aspect of fish that provides lateral stability while swimming. Generally fish have one or two dorsal fins.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0035160	biolink:NamedThing	maintenance of epithelial integrity, open tracheal system	Ensuring that tracheal tubes in an open tracheal system maintain their epithelial structure during the cell shape changes and movements that occur during the branching process.	tmpzr1t_l9r_go_relaxed.owl	maintenance of tracheal epithelial integrity													biological_process											owl:Class	
GO:0035152	biolink:NamedThing	regulation of tube architecture, open tracheal system	Ensuring that tracheal cells form and maintain tubular structures with the correct size and shape for their position in the network. This is essential for efficient flow of gases through the tracheal network.	tmpzr1t_l9r_go_relaxed.owl	regulation of tracheal tube architecture													biological_process											owl:Class	
GO:0006635	biolink:NamedThing	fatty acid beta-oxidation	A fatty acid oxidation process that results in the complete oxidation of a long-chain fatty acid. Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and occurs by successive cycles of reactions during each of which the fatty acid is shortened by a two-carbon fragment removed as acetyl coenzyme A; the cycle continues until only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively).	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0030753	biolink:NamedThing	8-hydroxyfuranocoumarin 8-O-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + xanthotoxol = S-adenosyl-L-homocysteine + xanthotoxin. Xanthotoxol is also known as 8-hydroxyfuranocoumarin and xanthotoxin as 8-methoxyfuranocoumarin.	tmpzr1t_l9r_go_relaxed.owl	S-adenosyl-L-methionine:8-hydroxyfuranocoumarin 8-O-methyltransferase activity|S-adenosyl-L-methionine:8-hydroxyfurocoumarin 8-O-methyltransferase activity|xanthotoxol 8-O-methyltransferase activity|furanocoumarin 8-O-methyl-transferase activity|furanocoumarin 8-methyltransferase activity|xanthotoxol methyltransferase activity|xanthotoxol O-methyltransferase activity|XMT activity|S-adenosyl-L-methionine:xanthotoxol O-methyltransferase activity				EC:2.1.1.70|KEGG_REACTION:R02982							GO:0030765		molecular_function											owl:Class	
GO:0097542	biolink:NamedThing	ciliary tip	Part of the cilium where the axoneme ends. The ciliary tip has been implicated in ciliary assembly and disassembly, as well as signal transduction.	tmpzr1t_l9r_go_relaxed.owl	cilium tip|cilial tip|flagellum tip|flagellar tip					Note that cilia and eukaryotic flagella are deemed to be equivalent.		pr	2013-12-12T11:12:22Z					cellular_component											owl:Class	
GO:1901602	biolink:NamedThing	dethiobiotin binding	Binding to dethiobiotin.	tmpzr1t_l9r_go_relaxed.owl								al	2012-11-08T14:09:14Z					molecular_function											owl:Class	
GO:1904792	biolink:NamedThing	positive regulation of shelterin complex assembly	Any process that activates or increases the frequency, rate or extent of shelterin complex assembly.	tmpzr1t_l9r_go_relaxed.owl	activation of Pot1-Tpz1 complex assembly|up regulation of Pot1 complex assembly|upregulation of telosome assembly|up regulation of Pot1-Tpz1 complex assembly|upregulation of shelterin complex formation|positive regulation of shelterin complex formation|up regulation of shelterin complex formation|up regulation of telosome assembly|up-regulation of telosome assembly|up-regulation of Pot1-Tpz1 complex assembly|activation of shelterin complex formation|activation of telosome assembly|positive regulation of Pot1-Tpz1 complex assembly|up-regulation of Pot1 complex assembly|activation of Pot1 complex assembly|positive regulation of Pot1 complex assembly|up-regulation of shelterin complex formation|upregulation of Pot1-Tpz1 complex assembly|positive regulation of telosome assembly|upregulation of Pot1 complex assembly							nc	2015-11-06T16:13:18Z					biological_process											owl:Class	
GO:0050356	biolink:NamedThing	tropine dehydrogenase activity	Catalysis of the reaction: NADP(+) + tropine = H(+) + NADPH + tropinone.	tmpzr1t_l9r_go_relaxed.owl	tropine:NADP+ 3alpha-oxidoreductase activity				MetaCyc:TROPINE-DEHYDROGENASE-RXN|RHEA:18357|EC:1.1.1.206|KEGG_REACTION:R02832									molecular_function											owl:Class	
GO:0008269	biolink:NamedThing	JAK pathway signal transduction adaptor activity	The binding activity of a molecule that brings together two molecules of the JAK signal transduction pathway, permitting them to function in a coordinated way.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0035591	biolink:NamedThing	signaling adaptor activity	The binding activity of a molecule that brings together two or more molecules in a signaling pathway, permitting those molecules to function in a coordinated way. Adaptor molecules themselves do not have catalytic activity.	tmpzr1t_l9r_go_relaxed.owl	signaling scaffold activity|signalling adaptor activity	https://github.com/geneontology/go-ontology/issues/19050				A signaling adaptor can bring together both protein and non-protein molecules within a signaling pathway. Scaffold proteins act in at least four ways: tethering signaling components, localizing these components to specific areas of the cell, regulating signal transduction by coordinating positive and negative feedback signals, and insulating correct signaling proteins from competing proteins (PMID:19104498).		bf	2010-11-05T11:22:01Z					molecular_function											owl:Class	
GO:0071387	biolink:NamedThing	cellular response to cortisol stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cortisol stimulus. Cortisol is the major natural glucocorticoid synthesized in the zona fasciculata of the adrenal cortex; it affects the metabolism of glucose, protein, and fats and has appreciable mineralocorticoid activity. It also regulates the immune system and affects many other functions.	tmpzr1t_l9r_go_relaxed.owl	cellular response to hydrocortisone stimulus							mah	2009-12-11T03:57:55Z					biological_process											owl:Class	
GO:0061515	biolink:NamedThing	myeloid cell development	The process whose specific outcome is the progression of a myeloid cell over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl								dph	2013-04-18T13:03:16Z					biological_process											owl:Class	
GO:0032383	biolink:NamedThing	regulation of intracellular cholesterol transport	Any process that modulates the frequency, rate or extent of the directed movement of cholesterol within cells.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0106350	biolink:NamedThing	octaprenyl pyrophosphate synthase activity	Catalysis of the reaction: (2E,6E)-farnesyl diphosphate + 5 isopentenyl diphosphate = 5 diphosphate + all-trans-octaprenyl diphosphate.	tmpzr1t_l9r_go_relaxed.owl					RHEA:27798|EC:2.5.1.90			hjd	2021-01-12T15:30:15Z					molecular_function											owl:Class	
GO:0008064	biolink:NamedThing	regulation of actin polymerization or depolymerization	Any process that modulates the frequency, rate or extent of the assembly or disassembly of actin filaments by the addition or removal of actin monomers from a filament.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0099115	biolink:NamedThing	chromosome, subtelomeric region	A region of the chromosome, adjacent to the telomere (on the centromeric side) that contains repetitive DNA and sometimes genes. This region is usually heterochromatin.	tmpzr1t_l9r_go_relaxed.owl	subtelomeric heterochromatin|subtelomere|nuclear subtelomeric heterochromatin|sub-telomeric heterochromatin	https://github.com/geneontology/go-ontology/issues/19086|https://github.com/geneontology/go-ontology/issues/22353			SO:0001997			vw	2014-07-18T13:32:59Z			GO:1990421|GO:1990707		cellular_component											owl:Class	
GO:0000781	biolink:NamedThing	chromosome, telomeric region	The end of a linear chromosome, required for the integrity and maintenance of the end. A chromosome telomere usually includes a region of telomerase-encoded repeats the length of which rarely exceeds 20 bp each and that permits the formation of a telomeric loop (T-loop). The telomeric repeat region is usually preceded by a sub-telomeric region that is gene-poor but rich in repetitive elements. Some telomeres only consist of the latter part (for eg. D. melanogaster telomeres).	tmpzr1t_l9r_go_relaxed.owl	telomere|nuclear chromosome, telomere|nuclear chromosome, telomeric region				SO:0000624	Note that this term can be used in place of the obsolete cellular component term 'telomere ; GO:0005696'. Use with caution because this term refers to a specific region of the chromosome and not a protein complex.						GO:0000784		cellular_component											owl:Class	
GO:0008267	biolink:NamedThing	poly-glutamine tract binding	Binding to a polyglutamine tract, i.e. a series of consecutive glutamine residues, in a protein.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0006398	biolink:NamedThing	mRNA 3'-end processing by stem-loop binding and cleavage	Any mRNA 3'-end processing that involves the binding to and cleavage of a stem-loop structure. For example, histone mRNAs contain a highly conserved stem-loop sequence at the 3' end of the mRNA with a 6 base pairs (bp) stem and a 4-nt loop. The mRNA is cleaved between these two elements, after the fourth or fifth nucleotide, which is typically an adenosine.	tmpzr1t_l9r_go_relaxed.owl	histone mRNA 3' end processing													biological_process											owl:Class	
GO:0031124	biolink:NamedThing	mRNA 3'-end processing	Any process involved in forming the mature 3' end of an mRNA molecule.	tmpzr1t_l9r_go_relaxed.owl	mRNA 3' end processing													biological_process											owl:Class	
GO:0010481	biolink:NamedThing	epidermal cell division	Any process resulting in the physical partitioning and separation of an epidermal cell, any of the cells making up the epidermis, into daughter cells.	tmpzr1t_l9r_go_relaxed.owl	hypodermal cell division													biological_process											owl:Class	
GO:0030397	biolink:NamedThing	membrane disassembly	The controlled breakdown of any cell membrane in the context of a normal process such as autophagy.	tmpzr1t_l9r_go_relaxed.owl	membrane degradation|membrane catabolism|membrane breakdown													biological_process											owl:Class	
GO:1900673	biolink:NamedThing	olefin metabolic process	The chemical reactions and pathways involving olefin.	tmpzr1t_l9r_go_relaxed.owl	olefin metabolism							tt	2012-05-22T04:24:42Z					biological_process											owl:Class	
GO:0005048	biolink:NamedThing	signal sequence binding	Binding to a signal sequence, a specific peptide sequence found on protein precursors or mature proteins that dictates where the mature protein is localized.	tmpzr1t_l9r_go_relaxed.owl	leader sequence binding|protein signal sequence binding|signal sequence receptor											GO:0008249		molecular_function											owl:Class	
GO:0015110	biolink:NamedThing	cyanate transmembrane transporter activity	Enables the transfer of cyanate, NCO-, the anion of cyanic acid, from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0102659	biolink:NamedThing	UDP-glucose: 4-methylthiobutylhydroximate S-glucosyltransferase activity	Catalysis of the reaction: UDP-alpha-D-glucose + 4-methylthiobutylhydroximate <=> H+ + 3-methylthiopropyl-desulfoglucosinolate + UDP.	tmpzr1t_l9r_go_relaxed.owl					EC:2.4.1.195|MetaCyc:RXN-2208									molecular_function											owl:Class	
GO:0110114	biolink:NamedThing	negative regulation of lipid transporter activity	Any process that decreases the frequency, rate, or extent of lipid transporter activity.	tmpzr1t_l9r_go_relaxed.owl								kmv	2018-07-06T19:21:44Z					biological_process											owl:Class	
GO:0052519	biolink:NamedThing	positive regulation of nutrient release by symbiont	Any process in which an organism activates, maintains or increases the frequency, rate or extent of the release of nutrients from a symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	positive regulation by host of nutrient release from symbiont|up regulation by host of nutrient release from symbiont|activation by host of nutrient release from symbiont|promotion of nutrient release from symbiont|upregulation by host of nutrient release from symbiont|up-regulation by host of nutrient release from symbiont|stimulation by host of nutrient release from symbiont													biological_process											owl:Class	
GO:0052460	biolink:NamedThing	modulation of nutrient release by symbiont	Any process in which an organism modulates the frequency, rate or extent of the release of nutrients from a symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	modulation by host of nutrient release from symbiont													biological_process											owl:Class	
GO:1900820	biolink:NamedThing	orlandin catabolic process	The chemical reactions and pathways resulting in the breakdown of orlandin.	tmpzr1t_l9r_go_relaxed.owl	orlandin degradation|orlandin breakdown|orlandin catabolism							di	2012-06-04T10:15:17Z					biological_process											owl:Class	
GO:1903773	biolink:NamedThing	negative regulation of viral budding via host ESCRT complex	Any process that stops, prevents or reduces the frequency, rate or extent of viral budding via host ESCRT complex.	tmpzr1t_l9r_go_relaxed.owl	downregulation of viral budding through the ESCRT machinery|inhibition of viral budding via host ESCRT complex|down regulation of viral budding through the ESCRT machinery|down regulation of viral budding via host ESCRT complex|down-regulation of viral budding through the ESCRT machinery|down-regulation of viral budding via host ESCRT complex|inhibition of viral budding through the ESCRT machinery|negative regulation of viral budding through the ESCRT machinery|downregulation of viral budding via host ESCRT complex							als	2015-01-06T16:20:53Z					biological_process											owl:Class	
GO:1903772	biolink:NamedThing	regulation of viral budding via host ESCRT complex	Any process that modulates the frequency, rate or extent of viral budding via host ESCRT complex.	tmpzr1t_l9r_go_relaxed.owl	regulation of host-assisted viral budding|regulation of viral budding through the ESCRT machinery							als	2015-01-06T16:20:43Z					biological_process											owl:Class	
GO:0071071	biolink:NamedThing	regulation of phospholipid biosynthetic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of phospholipids.	tmpzr1t_l9r_go_relaxed.owl	regulation of phospholipid anabolism|regulation of phospholipid formation|regulation of phospholipid synthesis|regulation of phospholipid biosynthesis							mah	2009-11-04T03:05:11Z					biological_process											owl:Class	
GO:0006204	biolink:NamedThing	IMP catabolic process	The chemical reactions and pathways resulting in the breakdown of IMP, inosine monophosphate.	tmpzr1t_l9r_go_relaxed.owl	IMP degradation|IMP catabolism|IMP breakdown													biological_process											owl:Class	
GO:0009304	biolink:NamedThing	tRNA transcription	The synthesis of transfer RNA (tRNA) from a DNA template.	tmpzr1t_l9r_go_relaxed.owl	tRNA biosynthesis|tRNA synthesis|tRNA biosynthetic process													biological_process											owl:Class	
GO:0098781	biolink:NamedThing	ncRNA transcription	The transcription of non (protein) coding RNA from a DNA template.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1900643	biolink:NamedThing	regulation of chanoclavine-I biosynthetic process	Any process that modulates the frequency, rate or extent of chanoclavine-I biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of chanoclavine-I anabolism|regulation of chanoclavine-I biosynthesis|regulation of chanoclavine-I formation|regulation of chanoclavine-I synthesis							di	2012-05-22T04:03:08Z					biological_process											owl:Class	
GO:0072708	biolink:NamedThing	response to sorbitol	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sorbitol stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to glucitol							mah	2012-04-11T03:40:57Z					biological_process											owl:Class	
GO:1990528	biolink:NamedThing	Rvs161p-Rvs167p complex	A protein complex that is involved in endocytosis in the yeast S. cerevisiae.	tmpzr1t_l9r_go_relaxed.owl								rb	2014-11-05T23:11:32Z					cellular_component											owl:Class	
GO:1903395	biolink:NamedThing	regulation of secondary cell septum biogenesis	Any process that modulates the frequency, rate or extent of secondary cell septum biogenesis.	tmpzr1t_l9r_go_relaxed.owl								di	2014-08-29T21:42:17Z					biological_process											owl:Class	
GO:0032563	biolink:NamedThing	dADP binding	Binding to dADP, deoxyadenosine diphosphate.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0006068	biolink:NamedThing	ethanol catabolic process	The chemical reactions and pathways resulting in the breakdown of ethanol, CH3-CH2-OH, a colorless, water-miscible, flammable liquid produced by alcoholic fermentation.	tmpzr1t_l9r_go_relaxed.owl	ethanol degradation|ethanol breakdown|ethanol catabolism													biological_process											owl:Class	
GO:0006067	biolink:NamedThing	ethanol metabolic process	The chemical reactions and pathways involving ethanol, CH3-CH2-OH, a colorless, water-miscible, flammable liquid produced by alcoholic fermentation.	tmpzr1t_l9r_go_relaxed.owl	ethanol metabolism													biological_process											owl:Class	
GO:1901103	biolink:NamedThing	gramicidin S biosynthetic process	The chemical reactions and pathways resulting in the formation of gramicidin S.	tmpzr1t_l9r_go_relaxed.owl	gramicidin S formation|gramicidin S anabolism|gramicidin S synthesis|gramicidin S biosynthesis							yaf	2012-07-11T02:31:00Z					biological_process											owl:Class	
GO:1901101	biolink:NamedThing	gramicidin S metabolic process	The chemical reactions and pathways involving gramicidin S.	tmpzr1t_l9r_go_relaxed.owl	gramicidin S metabolism							yaf	2012-07-11T02:30:26Z					biological_process											owl:Class	
GO:0010613	biolink:NamedThing	positive regulation of cardiac muscle hypertrophy	Any process that increases the rate, frequency or extent of the enlargement or overgrowth of all or part of the heart due to an increase in size (not length) of individual cardiac muscle fibers, without cell division.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1902866	biolink:NamedThing	regulation of retina development in camera-type eye	Any process that modulates the frequency, rate or extent of retina development in camera-type eye.	tmpzr1t_l9r_go_relaxed.owl	regulation of retinal development|regulation of retina development in camera-style eye							mr	2014-04-03T15:24:17Z					biological_process											owl:Class	
GO:0070605	biolink:NamedThing	regulation of (1->3)-alpha-glucan metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds.	tmpzr1t_l9r_go_relaxed.owl	regulation of 1,3-alpha-glucan metabolism|regulation of 1,3-alpha-glucan metabolic process|regulation of alpha-1,3 glucan metabolism|regulation of alpha-1,3 glucan metabolic process							mah	2009-04-29T01:20:12Z					biological_process											owl:Class	
GO:0046969	biolink:NamedThing	NAD-dependent histone deacetylase activity (H3-K9 specific)	Catalysis of the reaction: histone H3 N6-acetyl-L-lysine (position 9) + H2O = histone H3 L-lysine (position 9) + acetate. This reaction requires the presence of NAD, and represents the removal of an acetyl group from lysine at position 9 of the histone H3 protein.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-9604829									molecular_function											owl:Class	
GO:0017136	biolink:NamedThing	NAD-dependent histone deacetylase activity	Catalysis of the reaction: histone N6-acetyl-L-lysine + H2O = histone L-lysine + acetate. This reaction requires the presence of NAD, and represents the removal of an acetyl group from a histone.	tmpzr1t_l9r_go_relaxed.owl	SIR2													molecular_function											owl:Class	
GO:0008905	biolink:NamedThing	mannose-phosphate guanylyltransferase activity	Catalysis of the transfer of a phosphate group from GTP or GDP to a mannose molecule.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1902253	biolink:NamedThing	regulation of intrinsic apoptotic signaling pathway by p53 class mediator	Any process that modulates the frequency, rate or extent of intrinsic apoptotic signaling pathway by p53 class mediator.	tmpzr1t_l9r_go_relaxed.owl	regulation of signal transduction by p53 class mediator resulting in induction of apoptosis|regulation of intrinsic apoptotic signaling pathway by signal transduction by p53 class mediator							rl	2013-06-20T19:41:38Z					biological_process											owl:Class	
GO:0034588	biolink:NamedThing	piRNA catabolic process	The chemical reactions and pathways resulting in the breakdown of piRNAs, Piwi-associated RNAs, a class of 24- to 30-nucleotide RNA derived from repeat or complex DNA sequence elements and processed by a Dicer-independent mechanism.	tmpzr1t_l9r_go_relaxed.owl	piRNA breakdown|Piwi-associated RNA catabolic process|piRNA catabolism|piRNA degradation													biological_process											owl:Class	
GO:1905898	biolink:NamedThing	positive regulation of response to endoplasmic reticulum stress	Any process that activates or increases the frequency, rate or extent of response to endoplasmic reticulum stress.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of cellular response to endoplasmic reticulum stress|activation of cellular response to endoplasmic reticulum stress|upregulation of response to endoplasmic reticulum stress|positive regulation of cellular response to endoplasmic reticulum stress|up-regulation of ER stress response|positive regulation of ER stress response|upregulation of response to ER stress|up-regulation of response to ER stress|up regulation of cellular response to endoplasmic reticulum stress|up regulation of response to endoplasmic reticulum stress|up regulation of response to ER stress|activation of response to ER stress|up regulation of ER stress response|positive regulation of response to ER stress|upregulation of cellular response to endoplasmic reticulum stress|up-regulation of response to endoplasmic reticulum stress|upregulation of ER stress response|activation of response to endoplasmic reticulum stress|activation of ER stress response							bc	2017-02-01T11:43:03Z					biological_process											owl:Class	
GO:0047269	biolink:NamedThing	poly(ribitol-phosphate) N-acetylglucosaminyltransferase activity	Catalysis of the reaction: poly(ribitol phosphate) + UDP-N-acetyl-D-glucosamine = N-acetyl-D-glucosaminyl-poly(ribitol phosphate) + UDP.	tmpzr1t_l9r_go_relaxed.owl	UDP-N-acetyl-D-glucosamine:poly(ribitol-phosphate) N-acetyl-D-glucosaminyltransferase activity|uridine diphosphoacetylglucosamine-poly(ribitol phosphate) acetylglucosaminyltransferase activity|UDP acetylglucosamine-poly(ribitol phosphate) acetylglucosaminyltransferase activity				EC:2.4.1.70|MetaCyc:2.4.1.70-RXN|RHEA:21012									molecular_function											owl:Class	
GO:0008052	biolink:NamedThing	sensory organ boundary specification	The process in which boundaries between a sensory organ and the surrounding tissue are established and maintained.	tmpzr1t_l9r_go_relaxed.owl	sense organ boundary specification													biological_process											owl:Class	
GO:0010160	biolink:NamedThing	formation of animal organ boundary	The regionalization process that specifies animal organ primordium boundaries resulting in a restriction of organogenesis to a limited spatial domain and keeping the organ separate from surrounding tissues.	tmpzr1t_l9r_go_relaxed.owl	organ boundary specification											GO:0048862		biological_process											owl:Class	
GO:0060252	biolink:NamedThing	positive regulation of glial cell proliferation	Any process that activates or increases the rate or extent of glial cell proliferation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1990777	biolink:NamedThing	lipoprotein particle	A spherical particle containing non-covalently associated proteins and lipids. Examples are plasma lipoprotein particles which transport lipids in the blood or lymph.	tmpzr1t_l9r_go_relaxed.owl								pr	2015-06-18T08:42:53Z					cellular_component											owl:Class	
GO:0032994	biolink:NamedThing	protein-lipid complex	A macromolecular complex containing separate protein and lipid molecules.  Separate in this context means not covalently bound to each other.	tmpzr1t_l9r_go_relaxed.owl						Macromolecular complexes in which the lipid component is all covalently bound to protein are not considered protein-lipid complexes.								cellular_component											owl:Class	
GO:2000250	biolink:NamedThing	negative regulation of actin cytoskeleton reorganization	Any process that stops, prevents, or reduces the frequency, rate or extent of actin cytoskeleton reorganization.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of actin cytoskeleton reorganisation|negative regulation of actin cytoskeleton remodeling							vk	2010-11-11T01:25:29Z					biological_process											owl:Class	
GO:0031115	biolink:NamedThing	negative regulation of microtubule polymerization	Any process that stops, prevents, or reduces the frequency, rate or extent of microtubule polymerization.	tmpzr1t_l9r_go_relaxed.owl	downregulation of microtubule polymerization|down-regulation of microtubule polymerization|inhibition of microtubule polymerization|down regulation of microtubule polymerization													biological_process											owl:Class	
GO:0055038	biolink:NamedThing	recycling endosome membrane	The lipid bilayer surrounding a recycling endosome.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0098925	biolink:NamedThing	retrograde trans-synaptic signaling by nitric oxide, modulating synaptic transmission	Modulation of synaptic transmission by cell-cell signaling from postsynapse to presynapse, across the synaptic cleft, mediated by nitric oxide.	tmpzr1t_l9r_go_relaxed.owl						Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.								biological_process											owl:Class	
GO:1901353	biolink:NamedThing	positive regulation of phosphatidylglycerol biosynthetic process	Any process that activates or increases the frequency, rate or extent of phosphatidylglycerol biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	upregulation of phosphatidylglycerol biosynthesis|up-regulation of phosphatidylglycerol formation|positive regulation of phosphatidylglycerol synthesis|upregulation of phosphatidylglycerol anabolism|upregulation of phosphatidylglycerol synthesis|up regulation of phosphatidylglycerol synthesis|activation of phosphatidylglycerol biosynthesis|up regulation of phosphatidylglycerol biosynthetic process|upregulation of phosphatidylglycerol formation|positive regulation of phosphatidylglycerol anabolism|upregulation of phosphatidylglycerol biosynthetic process|up-regulation of phosphatidylglycerol anabolism|activation of phosphatidylglycerol biosynthetic process|activation of phosphatidylglycerol synthesis|up regulation of phosphatidylglycerol biosynthesis|up-regulation of phosphatidylglycerol biosynthesis|positive regulation of phosphatidylglycerol formation|up regulation of phosphatidylglycerol formation|activation of phosphatidylglycerol formation|positive regulation of phosphatidylglycerol biosynthesis|activation of phosphatidylglycerol anabolism|up regulation of phosphatidylglycerol anabolism|up-regulation of phosphatidylglycerol synthesis|up-regulation of phosphatidylglycerol biosynthetic process							dgf	2012-09-12T20:48:11Z					biological_process											owl:Class	
GO:1901351	biolink:NamedThing	regulation of phosphatidylglycerol biosynthetic process	Any process that modulates the frequency, rate or extent of phosphatidylglycerol biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of phosphatidylglycerol anabolism|regulation of phosphatidylglycerol biosynthesis|regulation of phosphatidylglycerol synthesis|regulation of phosphatidylglycerol formation							dgf	2012-09-12T20:46:37Z					biological_process											owl:Class	
GO:1901474	biolink:NamedThing	azole transmembrane transporter activity	Enables the directed movement of azoles, heterocyclic compound found in many biologically important substances, from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	azole transporter activity							tb	2012-10-04T20:00:27Z			GO:0045118		molecular_function											owl:Class	
GO:0061035	biolink:NamedThing	regulation of cartilage development	Any process that modulates the rate, frequency, or extent of cartilage development, the process whose specific outcome is the progression of the cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-02-09T03:41:35Z					biological_process											owl:Class	
GO:1900501	biolink:NamedThing	negative regulation of butyryl-CoA catabolic process to butyrate	Any process that stops, prevents or reduces the frequency, rate or extent of butyryl-CoA catabolic process to butyrate.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of butyryl-CoA catabolism to butyrate|down-regulation of butyryl-CoA catabolic process to butyrate|down-regulation of butyryl-CoA catabolism to butyrate|inhibition of butyryl-CoA catabolic process to butyrate|down regulation of butyryl-CoA catabolism to butyrate|inhibition of butyryl-CoA catabolism to butyrate|downregulation of butyryl-CoA catabolic process to butyrate|downregulation of butyryl-CoA catabolism to butyrate|down regulation of butyryl-CoA catabolic process to butyrate							tt	2012-05-02T03:56:30Z					biological_process											owl:Class	
GO:1900694	biolink:NamedThing	positive regulation of (+)-kotanin biosynthetic process	Any process that activates or increases the frequency, rate or extent of (+)-kotanin biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of (+)-kotanin biosynthetic process|up regulation of (+)-kotanin anabolism|up-regulation of (+)-kotanin anabolism|up regulation of (+)-kotanin formation|positive regulation of (+)-kotanin anabolism|activation of (+)-kotanin anabolism|positive regulation of (+)-kotanin biosynthesis|upregulation of (+)-kotanin anabolism|upregulation of (+)-kotanin biosynthesis|up-regulation of (+)-kotanin biosynthesis|positive regulation of (+)-kotanin synthesis|upregulation of (+)-kotanin biosynthetic process|activation of (+)-kotanin biosynthetic process|upregulation of (+)-kotanin synthesis|positive regulation of (+)-kotanin formation|up regulation of (+)-kotanin synthesis|up regulation of (+)-kotanin biosynthetic process|up-regulation of (+)-kotanin synthesis|up-regulation of (+)-kotanin formation|upregulation of (+)-kotanin formation|up regulation of (+)-kotanin biosynthesis|activation of (+)-kotanin biosynthesis|activation of (+)-kotanin synthesis|activation of (+)-kotanin formation							di	2012-05-22T04:53:33Z					biological_process											owl:Class	
GO:1900692	biolink:NamedThing	regulation of (+)-kotanin biosynthetic process	Any process that modulates the frequency, rate or extent of (+)-kotanin biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of (+)-kotanin formation|regulation of (+)-kotanin anabolism|regulation of (+)-kotanin synthesis|regulation of (+)-kotanin biosynthesis							di	2012-05-22T04:53:04Z					biological_process											owl:Class	
GO:0003429	biolink:NamedThing	growth plate cartilage chondrocyte morphogenesis	The process in which the structures of a chondrocyte in the growth plate cartilage are generated and organized.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-12-22T12:22:24Z					biological_process											owl:Class	
GO:0030654	biolink:NamedThing	beta-lactam antibiotic biosynthetic process	The chemical reactions and pathways resulting in the formation of a beta-lactam antibiotic, any member of a class of natural or semisynthetic antibiotics whose characteristic feature is a strained, four-membered beta-lactam ring. They include the penicillins and many of the cephalosporins.	tmpzr1t_l9r_go_relaxed.owl	beta-lactam antibiotic synthesis|beta-lactam antibiotic biosynthesis|beta-lactam antibiotic formation|beta-lactam antibiotic anabolism													biological_process											owl:Class	
GO:0033355	biolink:NamedThing	ascorbate glutathione cycle	A cyclic series of interconversions involving L-ascorbate and glutathione that scavenges hydrogen peroxide and reduces it to water, with concomitant oxidation of NADPH.	tmpzr1t_l9r_go_relaxed.owl	hydrogen peroxide detoxification				MetaCyc:PWY-2261									biological_process											owl:Class	
GO:0070109	biolink:NamedThing	positive regulation of interleukin-27-mediated signaling pathway	Any process that increases the rate, frequency or extent of the series of molecular events generated as a consequence of interleukin-27 binding to a cell surface receptor.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of IL-27-mediated signaling pathway|positive regulation of IL27RA/IL6ST signaling pathway|positive regulation of interleukin-27-mediated signalling pathway													biological_process											owl:Class	
GO:0015274	biolink:NamedThing	organellar voltage-gated chloride channel activity	Enables the transmembrane transfer of a chloride ion by a voltage-gated channel. The membrane is an organellar membrane.	tmpzr1t_l9r_go_relaxed.owl	organellar voltage-dependent chloride channel activity|organellar voltage gated chloride channel activity													molecular_function											owl:Class	
GO:0090326	biolink:NamedThing	positive regulation of locomotion involved in locomotory behavior	Any process that increases the frequency, rate, or extent of the self-propelled movement of a cell or organism from one location to another in a behavioral context; the aspect of locomotory behavior having to do with movement.	tmpzr1t_l9r_go_relaxed.owl								tb	2010-05-14T10:26:58Z					biological_process											owl:Class	
GO:0046822	biolink:NamedThing	regulation of nucleocytoplasmic transport	Any process that modulates the frequency, rate or extent of the directed movement of substances between the nucleus and the cytoplasm.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0010513	biolink:NamedThing	positive regulation of phosphatidylinositol biosynthetic process	Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of phosphatidylinositol.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0009188	biolink:NamedThing	ribonucleoside diphosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of a ribonucleoside diphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with diphosphate on the sugar.	tmpzr1t_l9r_go_relaxed.owl	ribonucleoside diphosphate anabolism|ribonucleoside diphosphate formation|ribonucleoside diphosphate biosynthesis|ribonucleoside diphosphate synthesis													biological_process											owl:Class	
GO:0032217	biolink:NamedThing	riboflavin transmembrane transporter activity	Enables the transfer of riboflavin from one side of a membrane to the other. Riboflavin (vitamin B2) is a water-soluble B-complex vitamin, converted in the cell to FMN and FAD, cofactors required for the function of flavoproteins.	tmpzr1t_l9r_go_relaxed.owl	riboflavin transporter activity				RHEA:35015|Reactome:R-HSA-3165230									molecular_function											owl:Class	
GO:0015318	biolink:NamedThing	inorganic molecular entity transmembrane transporter activity	Enables the transfer of an inorganic molecular entity from the outside of a cell to the inside of the cell across a membrane. An inorganic molecular entity is a molecular entity that contains no carbon.	tmpzr1t_l9r_go_relaxed.owl	inorganic uptake permease activity|inorganic solute uptake transmembrane transporter activity	https://github.com/geneontology/go-ontology/issues/14372												molecular_function											owl:Class	
GO:0030389	biolink:NamedThing	fructosamine metabolic process	The chemical reactions and pathways involving fructosamine, a fructose molecule containing an amino group in place of a hydroxyl group.	tmpzr1t_l9r_go_relaxed.owl	fructosamine metabolism													biological_process											owl:Class	
GO:0050349	biolink:NamedThing	triacetate-lactonase activity	Catalysis of the reaction: H(2)O + triacetate lactone = triacetate.	tmpzr1t_l9r_go_relaxed.owl	triacetic acid lactone hydrolase activity|TAL hydrolase activity|triacetate lactone hydrolase activity|triacetic lactone hydrolase activity|triacetolactone lactonohydrolase activity				RHEA:22260|EC:3.1.1.38|MetaCyc:TRIACETATE-LACTONASE-RXN|KEGG_REACTION:R03702									molecular_function											owl:Class	
GO:1903084	biolink:NamedThing	protein localization to condensed nuclear chromosome	A process in which a protein is transported to, or maintained in, a location within a condensed nuclear chromosome.	tmpzr1t_l9r_go_relaxed.owl	protein localisation to condensed nuclear chromosome|protein localisation in condensed nuclear chromosome|protein localization in condensed nuclear chromosome							kmv	2014-05-29T20:33:17Z					biological_process											owl:Class	
GO:2001010	biolink:NamedThing	negative regulation of plant-type cell wall cellulose biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of plant-type cell wall cellulose biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of cell wall cellulose biosynthesis|negative regulation of cellulose biosynthesis during cell wall biosynthesis							tt	2011-08-08T08:47:22Z					biological_process											owl:Class	
GO:0071922	biolink:NamedThing	regulation of cohesin loading	Any process that modulates the frequency, rate or extent of a process in which a cohesin complex is transported to, or maintained at, a part of a chromosome that is organized into chromatin.	tmpzr1t_l9r_go_relaxed.owl	regulation of cohesin association with chromatin|regulation of cohesin localisation to chromatin|regulation of cohesin localization to chromatin							mah	2010-09-28T11:13:35Z					biological_process											owl:Class	
GO:0009549	biolink:NamedThing	cellulose microfibril	A microfibril composed of cellulose arranged in orthogonal layers. Cellulose is a straight chain polysaccharide composed of B(14) linked glucose subunits. It is a major component of plant cell walls. Higher plant microfibrils are about 10nm in diameter and extremely long in relation to their width. The cellulose molecules are oriented parallel to the long axis of the microfibril in a paracrystalline array, which provides great tensile strength. The microfibrils are held in place by the wall matrix and their orientation is closely controlled by the cell.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0016102	biolink:NamedThing	diterpenoid biosynthetic process	The chemical reactions and pathways resulting in the formation of diterpenoid compounds, terpenoids with four isoprene units.	tmpzr1t_l9r_go_relaxed.owl	diterpene biosynthetic process|diterpenoid anabolism|diterpenoid synthesis|diterpene biosynthesis|diterpenoid formation|diterpenoid biosynthesis													biological_process											owl:Class	
GO:0090227	biolink:NamedThing	regulation of red or far-red light signaling pathway	Any process that modulates the rate, frequency or extent of the red or far-red signaling pathway, the series of molecular signals initiated upon sensing by photoreceptor molecules of red light or far red light.	tmpzr1t_l9r_go_relaxed.owl	regulation of red or far-red light signalling pathway|regulation of phytochrome signaling pathway							tb	2010-01-19T04:03:29Z					biological_process											owl:Class	
GO:1903613	biolink:NamedThing	regulation of protein tyrosine phosphatase activity	Any process that modulates the frequency, rate or extent of protein tyrosine phosphatase activity.	tmpzr1t_l9r_go_relaxed.owl	regulation of phosphotyrosine histone phosphatase activity|regulation of phosphoprotein phosphatase (phosphotyrosine) activity|regulation of PTPase activity|regulation of protein phosphotyrosine phosphatase activity|regulation of protein-tyrosine-phosphatase activity|regulation of phosphotyrosylprotein phosphatase activity|regulation of tyrosine O-phosphate phosphatase activity|regulation of phosphotyrosine phosphatase activity|regulation of PTP-phosphatase activity|regulation of tyrosylprotein phosphatase activity|regulation of PPT-phosphatase activity|regulation of phosphotyrosine protein phosphatase activity|regulation of protein-tyrosine-phosphate phosphohydrolase activity|regulation of [phosphotyrosine]protein phosphatase activity							sl	2014-11-18T01:11:38Z					biological_process											owl:Class	
GO:0001866	biolink:NamedThing	NK T cell proliferation	The expansion of a NK T cell population by cell division.	tmpzr1t_l9r_go_relaxed.owl	NT cell proliferation|natural T cell proliferation|NK T-cell proliferation|NK T-lymphocyte proliferation|NKT cell proliferation|natural killer T cell proliferation|NK T lymphocyte proliferation					Note that NK T cells are a distinct lineage of T cells expressing natural killer cell markers and having T cell receptors characterized by the usage of a restricted repertoire of variable region gene segments.								biological_process											owl:Class	
GO:0043646	biolink:NamedThing	cephalosporin biosynthetic process	The chemical reactions and pathways resulting in the formation of a cephalosporin, any of large class of tetracyclic triterpene broad-spectrum antibiotics similar both chemically and in their mode of action to penicillin, first isolated from the culture filtrates of mediterranean fungus acremonium (cephalosporium acremonium), and effective against gram-positive bacteria.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1903566	biolink:NamedThing	positive regulation of protein localization to cilium	Any process that activates or increases the frequency, rate or extent of protein localization to cilium.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of protein localization to cilium|up regulation of protein localization to cilium|activation of protein localization to cilium|upregulation of protein localization to cilium							krc	2014-10-24T20:58:28Z					biological_process											owl:Class	
GO:0009078	biolink:NamedThing	pyruvate family amino acid metabolic process	The chemical reactions and pathways involving any amino acid that requires pyruvate for its synthesis, e.g. alanine.	tmpzr1t_l9r_go_relaxed.owl	pyruvate family amino acid metabolism													biological_process											owl:Class	
GO:0051751	biolink:NamedThing	alpha-1,4-mannosyltransferase activity	Catalysis of the transfer of a mannose residue to an oligosaccharide, forming an alpha-(1->4) linkage.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1900793	biolink:NamedThing	shamixanthone biosynthetic process	The chemical reactions and pathways resulting in the formation of shamixanthone.	tmpzr1t_l9r_go_relaxed.owl	shamixanthone biosynthesis|shamixanthone synthesis|shamixanthone anabolism|shamixanthone formation							di	2012-06-04T09:40:49Z					biological_process											owl:Class	
GO:0006585	biolink:NamedThing	dopamine biosynthetic process from tyrosine	The chemical reactions and pathways resulting in the formation of dopamine (3,4-dihydroxyphenylethylamine) from L-tyrosine, via the metabolic precursor 3,4-dihydroxy-L-phenylalanine (L-dopa). Dopamine is a catecholamine neurotransmitter and a metabolic precursor of norepinephrine and epinephrine.	tmpzr1t_l9r_go_relaxed.owl	dopamine anabolism from tyrosine|dopamine synthesis from tyrosine|dopamine formation from tyrosine													biological_process											owl:Class	
GO:0042416	biolink:NamedThing	dopamine biosynthetic process	The chemical reactions and pathways resulting in the formation of dopamine, a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline.	tmpzr1t_l9r_go_relaxed.owl	dopamine synthesis|dopamine formation|dopamine biosynthesis|dopamine anabolism													biological_process											owl:Class	
GO:0033217	biolink:NamedThing	regulation of transcription from RNA polymerase II promoter in response to iron ion starvation	Modulation of the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of deprivation of iron ions.	tmpzr1t_l9r_go_relaxed.owl	regulation of transcription from RNA polymerase II promoter in response to iron deficiency													biological_process											owl:Class	
GO:1990139	biolink:NamedThing	protein localization to nuclear periphery	A process in which a protein is transported to, or maintained in, a location within the nuclear periphery.	tmpzr1t_l9r_go_relaxed.owl								mah	2013-07-09T13:35:49Z					biological_process											owl:Class	
GO:0000439	biolink:NamedThing	transcription factor TFIIH core complex	The 7 subunit core of TFIIH that is a part of either the general transcription factor holo-TFIIH or the nucleotide-excision repair factor 3 complex. In S. cerevisiae/humans the complex is composed of: Ssl2/XPB, Tfb1/p62, Tfb2/p52, Ssl1/p44, Tfb4/p34, Tfb5/p8 and Rad3/XPD.	tmpzr1t_l9r_go_relaxed.owl	SSL2-core TFIIH complex|core TFIIH complex											GO:0000441		cellular_component											owl:Class	
GO:0007142	biolink:NamedThing	male meiosis II	A cell cycle process comprising the steps by which a cell progresses through male meiosis II, the second meiotic division in the male germline.	tmpzr1t_l9r_go_relaxed.owl	male meiosis II nuclear division													biological_process											owl:Class	
GO:0007135	biolink:NamedThing	meiosis II	The second nuclear division of meiosis, in which the two chromatids in each chromosome are separated, resulting in four daughter nuclei from the two nuclei produced in meiosis II.	tmpzr1t_l9r_go_relaxed.owl	meiosis II nuclear division				Wikipedia:Meiosis#Meiosis_II									biological_process											owl:Class	
GO:0048301	biolink:NamedThing	positive regulation of isotype switching to IgD isotypes	Any process that activates or increases the frequency, rate or extent of isotype switching to IgD isotypes.	tmpzr1t_l9r_go_relaxed.owl	activation of isotype switching to IgD isotypes|positive regulation of class switching to IgD isotypes|positive regulation of isotype switch recombination to IgD isotypes|positive regulation of class switch recombination to IgD isotypes|stimulation of isotype switching to IgD isotypes|upregulation of isotype switching to IgD isotypes|up regulation of isotype switching to IgD isotypes|up-regulation of isotype switching to IgD isotypes													biological_process											owl:Class	
GO:0045830	biolink:NamedThing	positive regulation of isotype switching	Any process that activates or increases the frequency, rate or extent of isotype switching.	tmpzr1t_l9r_go_relaxed.owl	upregulation of isotype switching|positive regulation of class switching|activation of isotype switching|up regulation of isotype switching|up-regulation of isotype switching|positive regulation of class switch recombination|stimulation of isotype switching|positive regulation of isotype switch recombination													biological_process											owl:Class	
GO:0050146	biolink:NamedThing	nucleoside phosphotransferase activity	Catalysis of the reaction: a nucleotide + a 2'-deoxynucleoside = a nucleoside + a 2'-deoxynucleoside 5'-monophosphate.	tmpzr1t_l9r_go_relaxed.owl	nucleotide:nucleoside 5'-phosphotransferase activity|nucleotide:3'-deoxynucleoside 5'-phosphotransferase activity|nucleotide:2'-nucleoside 5'-phosphotransferase activity|nonspecific nucleoside phosphotransferase activity				Reactome:R-HSA-2162066|EC:2.7.1.77|RHEA:19961|MetaCyc:NUCLEOSIDE-PHOSPHOTRANSFERASE-RXN									molecular_function											owl:Class	
GO:0102278	biolink:NamedThing	N,N'-diacetylchitobiose synthase activity	Catalysis of the reaction: n H2O + chitin <=> N,N'-diacetylchitobiose.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-12554									molecular_function											owl:Class	
GO:0036123	biolink:NamedThing	histone H3-K9 dimethylation	The modification of histone H3 by addition of two methyl groups to lysine at position 9 of the histone.	tmpzr1t_l9r_go_relaxed.owl	histone H3 K9 dimethylation|histone lysine H3 K9 dimethylation							bf	2012-02-20T03:06:15Z					biological_process											owl:Class	
GO:0018014	biolink:NamedThing	N-terminal peptidyl-methionine methylation	The methylation of the N-terminal methionine of proteins to form the derivative N-methyl-L-methionine.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0064									biological_process											owl:Class	
GO:0018206	biolink:NamedThing	peptidyl-methionine modification	The modification of peptidyl-methionine.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0048549	biolink:NamedThing	positive regulation of pinocytosis	Any process that activates, maintains or increases the rate of pinocytosis. Pinocytosis is the process in which cells take in liquid material from their external environment; literally 'cell drinking'. Liquid is enclosed in vesicles, formed by invagination of the plasma membrane. These vesicles then move into the cell and pass their contents to endosomes.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of pinocytosis|up regulation of pinocytosis|upregulation of pinocytosis|stimulation of pinocytosis|activation of pinocytosis													biological_process											owl:Class	
GO:1903214	biolink:NamedThing	regulation of protein targeting to mitochondrion	Any process that modulates the frequency, rate or extent of protein targeting to mitochondrion.	tmpzr1t_l9r_go_relaxed.owl	regulation of mitochondrial translocation|regulation of protein-mitochondrial targeting|regulation of protein import into mitochondrion|regulation of protein targeting to mitochondria|regulation of mitochondrial protein import							bf	2014-07-24T10:17:13Z					biological_process											owl:Class	
GO:0034324	biolink:NamedThing	O-hexanoyltransferase activity	Catalysis of the transfer of a hexyl group to an oxygen atom on the acceptor molecule.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0034327	biolink:NamedThing	hexanoyltransferase activity	Catalysis of the transfer of a hexanoyl (CH3-[CH2]4-CO-) group to an acceptor molecule.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0006073	biolink:NamedThing	cellular glucan metabolic process	The chemical reactions and pathways involving glucans, polysaccharides consisting only of glucose residues, occurring at the level of an individual cell.	tmpzr1t_l9r_go_relaxed.owl	cellular glucan metabolism													biological_process											owl:Class	
GO:0071318	biolink:NamedThing	cellular response to ATP	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ATP (adenosine 5'-triphosphate) stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to adenosine 5'-triphosphate|cellular response to adenosine triphosphate							mah	2009-12-10T05:09:47Z					biological_process											owl:Class	
GO:0047902	biolink:NamedThing	formylaspartate deformylase activity	Catalysis of the reaction: N-formyl-L-aspartate + H2O = formate + L-aspartate.	tmpzr1t_l9r_go_relaxed.owl	formylaspartic formylase (formylase I, formylase II)|N-formyl-L-aspartate amidohydrolase activity				MetaCyc:FORMYLASPARTATE-DEFORMYLASE-RXN|EC:3.5.1.8|RHEA:22040									molecular_function											owl:Class	
GO:0044837	biolink:NamedThing	actomyosin contractile ring organization	A process which results in the assembly, arrangement of constituent parts, or disassembly of an actomyosin contractile ring.	tmpzr1t_l9r_go_relaxed.owl	cytokinesis, actomyosin contractile ring organization							jl	2014-02-26T15:31:31Z					biological_process											owl:Class	
GO:0035303	biolink:NamedThing	regulation of dephosphorylation	Any process that modulates the frequency, rate or extent of removal of phosphate groups from a molecule.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0019455	biolink:NamedThing	L-cysteine catabolic process via cystine, using cystine reductase	The chemical reactions and pathways resulting in the breakdown, via the compound cystine, of L-cysteine, catalyzed by the enzyme cystine reductase (EC:1.8.1.6).	tmpzr1t_l9r_go_relaxed.owl	L-cysteine breakdown via cystine, using cystine reductase|L-cysteine degradation via cystine, using cystine reductase													biological_process											owl:Class	
GO:0019453	biolink:NamedThing	L-cysteine catabolic process via cystine	The chemical reactions and pathways resulting in the breakdown of L-cysteine, via the intermediate cystine.	tmpzr1t_l9r_go_relaxed.owl	L-cysteine degradation via cystine|L-cysteine breakdown via cystine													biological_process											owl:Class	
GO:0048521	biolink:NamedThing	negative regulation of behavior	Any process that stops, prevents, or reduces the frequency, rate or extent of behavior, the internally coordinated responses (actions or inactions) of whole living organisms (individuals or groups) to internal or external stimuli.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of behavior|inhibition of behavior|down regulation of behavior|downregulation of behavior													biological_process											owl:Class	
GO:0060325	biolink:NamedThing	face morphogenesis	The process in which the anatomical structures of the face are generated and organized. The face is the ventral division of the head.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1903203	biolink:NamedThing	regulation of oxidative stress-induced neuron death	Any process that modulates the frequency, rate or extent of oxidative stress-induced neuron death.	tmpzr1t_l9r_go_relaxed.owl	regulation of neuron death in response to oxidative stress|regulation of neuronal cell death in response to oxidative stress							bf	2014-07-21T16:17:30Z					biological_process											owl:Class	
GO:2000340	biolink:NamedThing	positive regulation of chemokine (C-X-C motif) ligand 1 production	Any process that activates or increases the frequency, rate or extent of chemokine (C-X-C motif) ligand 1 production.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of CXCL1 production|positive regulation of keratinocyte derived chemokine production|positive regulation of SCYB1 production|positive regulation of KC production							mah	2011-02-01T10:46:33Z					biological_process											owl:Class	
GO:0016162	biolink:NamedThing	cellulose 1,4-beta-cellobiosidase activity	Catalysis of the hydrolysis of (1->4)-beta-D-glucosidic linkages in cellulose and cellotetraose, releasing cellobiose from the non-reducing ends of the chains.	tmpzr1t_l9r_go_relaxed.owl	1,4-beta-D-glucan cellobiohydrolase activity|exoglucanase activity|exo-cellobiohydrolase activity|cellobiohydrolase activity|1,4-beta-cellobiohydrolase activity|exo-1,4-beta-D-glucanase activity|C1 cellulase activity|cellobiosidase activity|avicelase activity|beta-1,4-glucan cellobiosylhydrolase activity|CBH 1|exocellobiohydrolase activity|cellobiohydrolase I|beta-1,4-glucan cellobiohydrolase activity|exo-beta-1,4-glucan cellobiohydrolase activity|1,4-beta-glucan cellobiosidase activity				MetaCyc:3.2.1.91-RXN|EC:3.2.1.91									molecular_function											owl:Class	
GO:0014712	biolink:NamedThing	positive regulation of branchiomeric skeletal muscle development	Any process that activates, maintains or increases the frequency, rate or extent of branchiomeric skeletal muscle development. Branchiomeric skeletal muscle development is the process whose specific outcome is the progression of the branchiomeric skeletal muscle over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0019702	biolink:NamedThing	protein-arginine N5-methyltransferase activity	Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to the delta-nitrogen atom of peptidyl-arginine residues. The reaction is S-adenosyl-L-methionine + [protein]-L-arginine = S-adenosyl-L-homocysteine + [protein]-N5-methyl-L-arginine.	tmpzr1t_l9r_go_relaxed.owl	protein-arginine delta-N-methyltransferase activity|type IV protein arginine methyltransferase activity|type IV PRMT activity|S-adenosyl-L-methionine:[protein]-L-arginine N-methyltransferase ([protein]-N5-methyl-L-arginine-forming)				RHEA:48116|EC:2.1.1.322	This enzyme, characterized from the yeast Saccharomyces cerevisiae, methylates the delta-nitrogen atom of arginine residues within proteins. Among its substrates are Arg67 of the ribosomal protein L12.								molecular_function											owl:Class	
GO:0070042	biolink:NamedThing	rRNA (uridine-N3-)-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing N3-methyluridine.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1905409	biolink:NamedThing	positive regulation of creatine transmembrane transporter activity	Any process that activates or increases the frequency, rate or extent of creatine transmembrane transporter activity.	tmpzr1t_l9r_go_relaxed.owl	activation of creatine transmembrane transporter activity|upregulation of creatine transmembrane transporter activity|up regulation of creatine transmembrane transporter activity|up-regulation of creatine transmembrane transporter activity							bc	2016-08-25T15:09:04Z					biological_process											owl:Class	
GO:0032281	biolink:NamedThing	AMPA glutamate receptor complex	An assembly of four or five subunits which form a structure with an extracellular N-terminus and a large loop that together form the ligand binding domain. The C-terminus is intracellular. The ionotropic glutamate receptor complex itself acts as a ligand gated ion channel; on binding glutamate, charged ions pass through a channel in the center of the receptor complex. The AMPA receptors mediate fast synaptic transmission in the CNS and are composed of subunits GluR1-4, products from separate genes. These subunits have an extracellular N-terminus and an intracellular C-terminus.	tmpzr1t_l9r_go_relaxed.owl	AMPA receptor|AMPA-selective glutamate receptor complex|alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex													cellular_component											owl:Class	
GO:0044059	biolink:NamedThing	modulation by symbiont of host endocrine process	The alteration by a symbiont organism of the functioning of a endocrine process, any of the hormonal, neural, and secretory processes that release products into the blood or lymph, in the host organism.	tmpzr1t_l9r_go_relaxed.owl	regulation by symbiont of host endocrine process													biological_process											owl:Class	
GO:0002164	biolink:NamedThing	larval development	The process whose specific outcome is the progression of the larva over time, from its formation to the mature structure. The larva is the early, immature form of an that at birth or hatching is fundamentally unlike its parent and must metamorphose before assuming the adult characters.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1990961	biolink:NamedThing	xenobiotic detoxification by transmembrane export across the plasma membrane	A process that reduces or removes the toxicity of a xenobiotic by exporting it outside the cell.	tmpzr1t_l9r_go_relaxed.owl	drug transmembrane export	https://github.com/geneontology/go-ontology/issues/17141						sl	2016-06-06T23:47:22Z					biological_process											owl:Class	
GO:0007283	biolink:NamedThing	spermatogenesis	The developmental process by which male germ line stem cells self renew or give rise to successive cell types resulting in the development of a spermatozoa.	tmpzr1t_l9r_go_relaxed.owl	generation of spermatozoa				Wikipedia:Spermatogenesis									biological_process											owl:Class	
GO:0043865	biolink:NamedThing	methionine transmembrane transporter activity	Enables the transfer of methionine from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	methionine importing activity|methionine-importing activity|methionine importer|methionine importer activity							pr	2013-11-15T10:35:04Z			GO:1990240		molecular_function											owl:Class	
GO:0070668	biolink:NamedThing	positive regulation of mast cell proliferation	Any process that activates or increases the rate or extent of mast cell proliferation.	tmpzr1t_l9r_go_relaxed.owl	up regulation of mast cell proliferation|upregulation of mast cell proliferation|activation of mast cell proliferation|stimulation of mast cell proliferation|up-regulation of mast cell proliferation							mah	2009-05-28T05:48:30Z					biological_process											owl:Class	
GO:0070666	biolink:NamedThing	regulation of mast cell proliferation	Any process that modulates the frequency, rate or extent of mast cell proliferation.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-05-28T05:40:43Z					biological_process											owl:Class	
GO:0033492	biolink:NamedThing	esculetin metabolic process	The chemical reactions and pathways involving esculetin, 6,7-dihydroxycoumarin.	tmpzr1t_l9r_go_relaxed.owl	esculetin metabolism													biological_process											owl:Class	
GO:0072741	biolink:NamedThing	protein localization to cell division site	A cellular protein localization process in which a protein is transported to, or maintained at, the site of cell division.	tmpzr1t_l9r_go_relaxed.owl	protein localisation to cell division site							mah	2012-08-16T11:51:48Z					biological_process											owl:Class	
GO:1900319	biolink:NamedThing	negative regulation of methane biosynthetic process from dimethylamine	Any process that stops, prevents or reduces the frequency, rate or extent of methane biosynthetic process from dimethylamine.	tmpzr1t_l9r_go_relaxed.owl	downregulation of methane biosynthetic process from dimethylamine|inhibition of methane biosynthetic process from dimethylamine|down regulation of methane biosynthetic process from dimethylamine|down-regulation of methane biosynthetic process from dimethylamine							tt	2012-04-06T01:43:31Z					biological_process											owl:Class	
GO:0005124	biolink:NamedThing	scavenger receptor binding	Binding to scavenger receptors, a family of proteins that are expressed on myeloid cells and are involved in the uptake of effete cellular components and foreign particles.	tmpzr1t_l9r_go_relaxed.owl	scavenger receptor ligand													molecular_function											owl:Class	
GO:1990613	biolink:NamedThing	mitochondrial membrane fusion	The joining of two lipid bilayers that surround the mitochondria.	tmpzr1t_l9r_go_relaxed.owl								vw	2015-01-21T06:58:18Z					biological_process											owl:Class	
GO:0062145	biolink:NamedThing	L-propargylglycine--L-glutamate ligase activity	Catalysis of the reaction: ATP + L-glutamate + L-propargylglycine = ADP + H(+) + L-gamma-glutamyl-L-propargylglycine + phosphate.	tmpzr1t_l9r_go_relaxed.owl					RHEA:59896			dph	2019-09-02T16:56:59Z					molecular_function											owl:Class	
GO:0090386	biolink:NamedThing	phagosome maturation involved in apoptotic cell clearance	A process that is carried out at the cellular level which results in the arrangement of constituent parts of a phagosome within a cell and contributes to apoptotic cell clearance. Phagosome maturation begins with endocytosis and formation of the early phagosome and ends with the formation of the hybrid organelle, the phagolysosome.	tmpzr1t_l9r_go_relaxed.owl								tb	2010-10-27T10:57:39Z					biological_process											owl:Class	
GO:0090382	biolink:NamedThing	phagosome maturation	A process that is carried out at the cellular level which results in the arrangement of constituent parts of a phagosome within a cell. Phagosome maturation begins with endocytosis and formation of the early phagosome and ends with the formation of the hybrid organelle, the phagolysosome.	tmpzr1t_l9r_go_relaxed.owl								tb	2010-10-19T11:10:34Z					biological_process											owl:Class	
GO:0080116	biolink:NamedThing	glucuronoxylan glucuronosyltransferase activity	Catalysis of the transfer of glucuronate to the xylan backbone of glucuronoxylan molecule.	tmpzr1t_l9r_go_relaxed.owl								dhl	2009-04-27T03:33:49Z					molecular_function											owl:Class	
GO:0015020	biolink:NamedThing	glucuronosyltransferase activity	Catalysis of the reaction: UDP-glucuronate + acceptor = UDP + acceptor beta-D-glucuronoside.	tmpzr1t_l9r_go_relaxed.owl	3-alpha-hydroxysteroid UDP-glucuronosyltransferase activity|p-nitrophenol UDP-glucuronosyltransferase activity|UDPGA-glucuronyltransferase activity|p-nitrophenylglucuronosyltransferase activity|estrone UDPglucuronosyltransferase activity|1-naphthol-UDP-glucuronosyltransferase activity|UDP-glucuronate beta-D-glucuronosyltransferase (acceptor-unspecific)|4-methylumbelliferone UDP-glucuronosyltransferase activity|3-OH androgenic UDPGT activity|pnp-UDPGT activity|UDPglucuronate beta-D-glucuronosyltransferase (acceptor-unspecific) activity|ciramadol UDP-glucuronyltransferase activity|UDPGT activity|phenyl-UDP-glucuronosyltransferase activity|UDPGA transferase activity|uridine 5'-diphosphoglucuronyltransferase activity|4-nitrophenol UDPGT activity|4-hydroxybiphenyl UDP-glucuronosyltransferase activity|p-hydroxybiphenyl UDP glucuronyltransferase activity|uridine diphosphate glucuronyltransferase activity|uridine diphosphoglucuronate-bilirubin glucuronoside glucuronosyltransferase activity|uridine diphosphoglucuronate-estriol 16alpha-glucuronosyltransferase activity|uridine diphosphoglucuronate-bilirubin glucuronosyltransferase activity|UDP glucuronic acid transferase activity|uridine diphosphoglucuronate-4-hydroxybiphenyl glucuronosyltransferase activity|bilirubin uridine diphosphoglucuronyltransferase activity|uridine diphosphoglucuronate-estriol 16-alpha-glucuronosyltransferase activity|bilirubin UDPGT activity|UDP glucuronate-estradiol-glucuronosyltransferase activity|17-OH steroid UDPGT activity|UDP-glucuronate-4-hydroxybiphenyl glucuronosyltransferase activity|uridine diphosphoglucuronate-estriol glucuronosyltransferase activity|bilirubin monoglucuronide glucuronyltransferase activity|PNP-UDPGT|uridine diphosphoglucuronate-estradiol glucuronosyltransferase activity|17-beta-hydroxysteroid UDP-glucuronosyltransferase activity|p-phenylphenol glucuronyltransferase activity|estriol UDPglucuronosyltransferase activity|uridine diphosphoglucuronyltransferase activity|bilirubin glucuronyltransferase activity|bilirubin UDP-glucuronosyltransferase activity|uridine diphosphoglucuronate-1,2-diacylglycerol glucuronosyltransferase activity|4-nitrophenol UDP-glucuronyltransferase activity|p-nitrophenol UDP-glucuronyltransferase activity|UDP glucuronyltransferase activity|GT activity|17beta-hydroxysteroid UDP-glucuronosyltransferase activity|UDP glucuronosyltransferase activity|uridine diphosphoglucuronosyltransferase activity|UDP-glucuronate-bilirubin glucuronyltransferase activity|UDP glucuronate-estriol glucuronosyltransferase activity|3alpha-hydroxysteroid UDP-glucuronosyltransferase activity|morphine glucuronyltransferase activity|1-naphthol glucuronyltransferase activity|UDP-glucuronosyltransferase activity|UDP-glucuronyltransferase activity				Reactome:R-HSA-174916|MetaCyc:UDP-GLUCURONOSYLTRANSFERASE-RXN|Reactome:R-HSA-9036104|Reactome:R-HSA-9638097|Reactome:R-HSA-159194|Reactome:R-HSA-5604975|Reactome:R-HSA-9632038|Reactome:R-HSA-159179|Reactome:R-HSA-5604954|Reactome:R-HSA-5617143|EC:2.4.1.17|RHEA:21032|Reactome:R-HSA-8941701|Reactome:R-HSA-174931|Reactome:R-HSA-9632039|Reactome:R-HSA-2162099|Reactome:R-HSA-9036102							GO:0003981		molecular_function											owl:Class	
GO:1903806	biolink:NamedThing	L-isoleucine import across plasma membrane	The directed movement of L-isoleucine from outside of a cell, across the plasma membrane and into the cytosol.	tmpzr1t_l9r_go_relaxed.owl	L-isoleucine import into cell|L-isoleucine import|isoleucine import							tb	2012-10-01T11:10:51Z			GO:0090476|GO:0090477		biological_process											owl:Class	
GO:0006396	biolink:NamedThing	RNA processing	Any process involved in the conversion of one or more primary RNA transcripts into one or more mature RNA molecules.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Post-transcriptional_modification							GO:0006394		biological_process											owl:Class	
GO:0033242	biolink:NamedThing	negative regulation of cellular amine catabolic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of amines.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of amine catabolism|negative regulation of amine breakdown|negative regulation of amine degradation													biological_process											owl:Class	
GO:0019355	biolink:NamedThing	nicotinamide nucleotide biosynthetic process from aspartate	The chemical reactions and pathways resulting in the formation of nicotinamide nucleotide from other compounds, including aspartate.	tmpzr1t_l9r_go_relaxed.owl	nicotinamide nucleotide anabolism from aspartate|nicotinamide nucleotide synthesis from aspartate|nicotinamide nucleotide formation from aspartate													biological_process											owl:Class	
GO:0044614	biolink:NamedThing	nuclear pore cytoplasmic filaments	Filamentous extensions on cytoplasmic face of the nuclear pore complex (NPC). In S. cerevisiae, Nup159p, Nup82p, and Nup42p contribute to the cytoplasmic filaments. In vertebrates, Nup358 is a major component.	tmpzr1t_l9r_go_relaxed.owl	cytoplasmic fibers of the nuclear pore complex|cytoplasmic fibers of the NPC							jl	2012-06-20T01:28:18Z					cellular_component											owl:Class	
GO:0060910	biolink:NamedThing	negative regulation of DNA replication initiation involved in plasmid copy number maintenance	Any process that decreases the frequency, rate or extent of initiation of plasmid DNA replication that contributes to copy number maintenance.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-09-04T02:56:29Z					biological_process											owl:Class	
GO:0009176	biolink:NamedThing	pyrimidine deoxyribonucleoside monophosphate metabolic process	The chemical reactions and pathways involving pyrimidine deoxynucleoside monophosphate, a compound consisting of a pyrimidine base linked to a deoxyribose sugar esterified with phosphate on the sugar.	tmpzr1t_l9r_go_relaxed.owl	pyrimidine deoxyribonucleoside monophosphate metabolism													biological_process											owl:Class	
GO:0010191	biolink:NamedThing	mucilage metabolic process	The chemical reactions and pathways involving mucilage, a gelatinous substance secreted by plants.	tmpzr1t_l9r_go_relaxed.owl	mucilage metabolism													biological_process											owl:Class	
GO:0035151	biolink:NamedThing	regulation of tube size, open tracheal system	Ensuring that an epithelial tube in an open tracheal system is of the correct length and diameter. Tracheal tubes undergo highly regulated tube-size increases during development, expanding up to 40 times their initial size by the end of larval life. Tube size appears to be controlled by regulation of apical membrane expansion and secretion, rather than by changes in cell number, size or shape.	tmpzr1t_l9r_go_relaxed.owl	regulation of tracheal tube size													biological_process											owl:Class	
GO:0060593	biolink:NamedThing	Wnt signaling pathway involved in mammary gland specification	The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of a cell in the epidermis resulting in the formation of the mammary line. The mammary line is a ridge of epidermal cells that will form the mammary placodes.	tmpzr1t_l9r_go_relaxed.owl	Wnt receptor signalling pathway involved in mammary gland specification|Wnt receptor signaling pathway involved in mammary gland specification|Wnt-activated signaling pathway involved in mammary gland specification							dph	2009-05-13T09:41:37Z					biological_process											owl:Class	
GO:0033196	biolink:NamedThing	tryparedoxin peroxidase activity	Catalysis of the reaction: tryparedoxin + hydrogen peroxide = tryparedoxin disulfide + H2O.	tmpzr1t_l9r_go_relaxed.owl	TXNPx activity				MetaCyc:1.11.1.15-RXN									molecular_function											owl:Class	
GO:0102780	biolink:NamedThing	sitosterol hydroxylase activity	Catalysis of the reaction: H+ + sitosterol + O2 + NADPH <=> (22alpha)-hydroxy-sitosterol + H2O + NADP.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-7876									molecular_function											owl:Class	
GO:0140319	biolink:NamedThing	receptor decoy activity	Recognizing, binding and sequestering a specific receptor ligand to prevent it from binding to its regular receptor.	tmpzr1t_l9r_go_relaxed.owl	decoy receptor|decoy death receptor activity							pg	2019-04-02T10:57:46Z			GO:0005040		molecular_function											owl:Class	
GO:0061365	biolink:NamedThing	positive regulation of triglyceride lipase activity	Any process that increases the activity of triglyceride lipase.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of TAG activity							dph	2010-10-15T08:27:22Z					biological_process											owl:Class	
GO:0090013	biolink:NamedThing	regulation of transforming growth factor beta receptor signaling pathway involved in primitive streak formation	Any process that modulates the frequency, rate or extent of any TGF-beta receptor signaling pathway that contributes to the formation of the primitive streak.	tmpzr1t_l9r_go_relaxed.owl	regulation of transforming growth factor beta receptor signalling pathway involved in primitive streak formation							tb	2009-07-29T10:54:44Z					biological_process											owl:Class	
GO:1902655	biolink:NamedThing	aromatic primary alcohol biosynthetic process	The chemical reactions and pathways resulting in the formation of aromatic primary alcohol.	tmpzr1t_l9r_go_relaxed.owl	aromatic primary alcohol formation|aromatic primary alcohol synthesis|aromatic primary alcohol biosynthesis|aromatic primary alcohol anabolism							tt	2014-01-22T10:47:30Z					biological_process											owl:Class	
GO:1902654	biolink:NamedThing	aromatic primary alcohol metabolic process	The chemical reactions and pathways involving aromatic primary alcohol.	tmpzr1t_l9r_go_relaxed.owl	aromatic primary alcohol metabolism							tt	2014-01-22T10:47:21Z					biological_process											owl:Class	
GO:0032769	biolink:NamedThing	negative regulation of monooxygenase activity	Any process that stops or reduces the activity of a monooxygenase.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of monooxygenase activity|inhibition of monooxygenase activity|down regulation of monooxygenase activity|downregulation of monooxygenase activity													biological_process											owl:Class	
GO:0033072	biolink:NamedThing	vancomycin biosynthetic process	The chemical reactions and pathways leading to the formation of vancomycin, (3S,6R,7R,11R,23S,26S,30aS,36R,38aR)-44-[2-O-(3-amino-2,3,6-trideoxy-3-C-methyl-alpha-L-lyxo-hexopyranosyl)-beta-D-glucopyranosyloxy]-3-(carbamoylmethyl)-10,19-dichloro-2,3,4,5,6,7,23,25,26,36,37,38,38a-tetradecahydro-7,22,28,30,32-pentahydroxy-6-(N-methyl-D-leucyl)-2,5,24,38,39-pentaoxo-1H,22H-23,36-(epiminomethano)-8,11:18,21-dietheno-13,16:31,35-di(metheno)[1,6,9]oxadiazacyclohexadecino[4,5-m][10,2,16]benzoxadiazacyclotetracosine-26-carboxylic acid, a complex glycopeptide from Streptomyces orientalis that inhibits a specific step in the synthesis of the peptidoglycan layer in Gram-positive bacteria.	tmpzr1t_l9r_go_relaxed.owl	vancomycin formation|vancomycin anabolism|vancomycin synthesis|vancomycin biosynthesis													biological_process											owl:Class	
GO:0034571	biolink:NamedThing	4'-(2-hydroxyisopropyl)phenylurea amidohydrolase activity	Catalysis of the reaction: 4'-(2-hydroxyisopropyl)phenylurea + H2O = 4'-(2-hydroxyisopropyl)phenylaniline + carbamic acid.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0895									molecular_function											owl:Class	
GO:0031683	biolink:NamedThing	G-protein beta/gamma-subunit complex binding	Binding to a complex of G-protein beta/gamma subunits.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0030906	biolink:NamedThing	retromer, cargo-selective complex	The trimeric subcomplex of the retromer, believed to be closely associated with the membrane. This trimeric complex is responsible for recognizing and binding to cargo molecules. The complex comprises three Vps proteins in both yeast and mammalian cells: Vps35p, Vps29p, and Vps26p in yeast, and VPS35, VPS29 and VPS26A or VPS26B in mammals.	tmpzr1t_l9r_go_relaxed.owl	retromer CSC|retromer complex, inner shell|retromer, cargo recognition complex|cargo-selective retromer subcomplex|retromer, CRC													cellular_component											owl:Class	
GO:0046126	biolink:NamedThing	pyrimidine deoxyribonucleoside biosynthetic process	The chemical reactions and pathways resulting in the formation of any one of a family of organic molecules consisting of a pyrimidine base covalently bonded to a sugar deoxyribose (a deoxyribonucleoside).	tmpzr1t_l9r_go_relaxed.owl	pyrimidine deoxyribonucleoside formation|pyrimidine deoxyribonucleoside biosynthesis|pyrimidine deoxyribonucleoside anabolism|pyrimidine deoxyribonucleoside synthesis													biological_process											owl:Class	
GO:0046134	biolink:NamedThing	pyrimidine nucleoside biosynthetic process	The chemical reactions and pathways resulting in the formation of one of a family of organic molecules consisting of a pyrimidine base covalently bonded to a sugar ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside).	tmpzr1t_l9r_go_relaxed.owl	pyrimidine nucleoside synthesis|pyrimidine nucleoside anabolism|pyrimidine nucleoside formation|pyrimidine nucleoside biosynthesis													biological_process											owl:Class	
GO:0051236	biolink:NamedThing	establishment of RNA localization	The directed movement of RNA to a specific location.	tmpzr1t_l9r_go_relaxed.owl	RNA positioning|RNA recruitment|establishment of RNA localisation													biological_process											owl:Class	
GO:0042997	biolink:NamedThing	negative regulation of Golgi to plasma membrane protein transport	Any process that stops, prevents, or reduces the frequency, rate or extent of the transport of proteins from the Golgi to the plasma membrane.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of Golgi to plasma membrane protein transport|downregulation of Golgi to plasma membrane protein transport|inhibition of Golgi to plasma membrane protein transport|down regulation of Golgi to plasma membrane protein transport													biological_process											owl:Class	
GO:1903197	biolink:NamedThing	positive regulation of L-dopa biosynthetic process	Any process that activates or increases the frequency, rate or extent of L-dopa biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	upregulation of L-dopa synthesis|up-regulation of L-dopa formation|activation of L-dopa anabolism|up regulation of L-dopa biosynthesis|upregulation of L-dopa formation|upregulation of L-dopa biosynthetic process|up-regulation of L-dopa biosynthetic process|upregulation of L-dopa anabolism|up regulation of L-dopa synthesis|positive regulation of L-dopa formation|up regulation of L-dopa anabolism|up-regulation of L-dopa biosynthesis|upregulation of L-dopa biosynthesis|activation of L-dopa biosynthesis|up regulation of L-dopa formation|activation of L-dopa synthesis|positive regulation of L-dopa biosynthesis|positive regulation of L-dopa synthesis|up regulation of L-dopa biosynthetic process|activation of L-dopa biosynthetic process|positive regulation of L-dopa anabolism|activation of L-dopa formation|up-regulation of L-dopa synthesis|up-regulation of L-dopa anabolism							bf	2014-07-21T09:12:49Z					biological_process											owl:Class	
GO:0035307	biolink:NamedThing	positive regulation of protein dephosphorylation	Any process that activates or increases the frequency, rate or extent of removal of phosphate groups from a protein.	tmpzr1t_l9r_go_relaxed.owl	upregulation of protein amino acid dephosphorylation|up-regulation of protein amino acid dephosphorylation|up regulation of protein amino acid dephosphorylation|stimulation of protein amino acid dephosphorylation|positive regulation of protein amino acid dephosphorylation|activation of protein amino acid dephosphorylation													biological_process											owl:Class	
GO:0106408	biolink:NamedThing	diadenylate cyclase activity	Catalysis of the reaction: 2 ATP = 3',3'-c-di-AMP + 2 diphosphate.	tmpzr1t_l9r_go_relaxed.owl	cyclic-di-AMP synthase				EC:2.7.7.85|RHEA:35655|MetaCyc:RXN-14338			hjd	2021-10-29 14:53:01+00:00					molecular_function											owl:Class	
GO:0090266	biolink:NamedThing	regulation of mitotic cell cycle spindle assembly checkpoint	Any process that modulates the rate, frequency, or extent of the mitotic cell cycle spindle assembly checkpoint, a cell cycle checkpoint that delays the metaphase/anaphase transition of a mitotic nuclear division until the spindle is correctly assembled and chromosomes are attached to the spindle.	tmpzr1t_l9r_go_relaxed.owl								tb	2010-02-05T02:06:37Z					biological_process											owl:Class	
GO:0005324	biolink:NamedThing	long-chain fatty acid transporter activity	Enables the transfer of long-chain fatty acids from one side of a membrane to the other. A long-chain fatty acid is a fatty acid with a chain length between C13 and C22.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-434381|Reactome:R-HSA-2046087|Reactome:R-HSA-390393|Reactome:R-HSA-5684043|Reactome:R-HSA-2046093|Reactome:R-HSA-382575							GO:0008562|GO:0005325		molecular_function											owl:Class	
GO:0033648	biolink:NamedThing	host intracellular membrane-bounded organelle	Organized structure of distinctive morphology and function, as found in host cells, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	host intracellular membrane-enclosed organelle													cellular_component											owl:Class	
GO:0033647	biolink:NamedThing	host intracellular organelle	Organized structure of distinctive morphology and function, occurring within the host cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0034760	biolink:NamedThing	negative regulation of iron ion transmembrane transport	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of iron ions from one side of a membrane to the other by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	inhibition of transmembrane iron ion transport|negative regulation of transmembrane iron ion transport|downregulation of transmembrane iron ion transport|negative regulation of transmembrane iron transport|down regulation of transmembrane iron ion transport|negative regulation of iron ion membrane transport|down-regulation of transmembrane iron ion transport													biological_process											owl:Class	
GO:0050877	biolink:NamedThing	nervous system process	A organ system process carried out by any of the organs or tissues of neurological system.	tmpzr1t_l9r_go_relaxed.owl	pan-neural process|neurological system process|neurophysiological process	https://github.com/geneontology/go-ontology/issues/13824												biological_process											owl:Class	
GO:2000044	biolink:NamedThing	negative regulation of cardiac cell fate specification	Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac cell fate specification.	tmpzr1t_l9r_go_relaxed.owl								tb	2010-08-19T09:01:10Z					biological_process											owl:Class	
GO:0003307	biolink:NamedThing	regulation of Wnt signaling pathway involved in heart development	Any process that modulates the rate, frequency, or extent of the series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of the target cell, resulting a change in cell state that contributes to the progression of the heart over time.	tmpzr1t_l9r_go_relaxed.owl	regulation of Wnt-activated signaling pathway involved in heart development|regulation of Wnt receptor signalling pathway involved in heart development|regulation of Wnt receptor signaling pathway involved in heart development							dph	2009-10-22T12:32:10Z					biological_process											owl:Class	
GO:0032938	biolink:NamedThing	negative regulation of translation in response to oxidative stress	Any process that stops, prevents, or reduces the frequency, rate or extent of translation as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0061757	biolink:NamedThing	leukocyte adhesion to arterial endothelial cell	The attachment of a leukocyte to an arterial endothelial cell via adhesion molecules.	tmpzr1t_l9r_go_relaxed.owl								dph	2016-02-29T16:49:38Z					biological_process											owl:Class	
GO:1905322	biolink:NamedThing	positive regulation of mesenchymal stem cell migration	Any process that activates or increases the frequency, rate or extent of mesenchymal stem cell migration.	tmpzr1t_l9r_go_relaxed.owl	upregulation of mesenchymal stem cell migration|up regulation of mesenchymal stem cell migration|activation of mesenchymal stem cell migration|up-regulation of mesenchymal stem cell migration							sl	2016-07-15T22:19:29Z					biological_process											owl:Class	
GO:1901846	biolink:NamedThing	positive regulation of cell communication by electrical coupling involved in cardiac conduction	Any process that activates or increases the frequency, rate or extent of cell communication by electrical coupling involved in cardiac conduction.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of cell communication by electrical coupling involved in cardiac conduction|up regulation of cell communication by electrical coupling involved in cardiac conduction|upregulation of cell communication by electrical coupling involved in cardiac conduction|activation of cell communication by electrical coupling involved in cardiac conduction							rl	2013-01-24T19:15:49Z					biological_process											owl:Class	
GO:0071106	biolink:NamedThing	adenosine 3',5'-bisphosphate transmembrane transport	The process in which adenosine 3',5'-bisphosphate is transported across a membrane.	tmpzr1t_l9r_go_relaxed.owl	adenosine 3',5'-diphosphate transport|adenosine 3',5'-bisphosphate membrane transport|adenosine 3'-phosphate-5'-phosphate transmembrane transport					Note that this term is not intended for use in annotating lateral movement within membranes.		mah	2009-11-12T10:40:49Z					biological_process											owl:Class	
GO:0072530	biolink:NamedThing	purine-containing compound transmembrane transport	The process in which a purine-containing compound is transported across a membrane. A purine-containing compound is any compound that contains purine or a formal derivative thereof.	tmpzr1t_l9r_go_relaxed.owl	purine-containing compound membrane transport					Note that this term is not intended for use in annotating lateral movement within membranes.		mah	2011-01-05T01:45:14Z					biological_process											owl:Class	
GO:0070490	biolink:NamedThing	protein pupylation	The process in which a Pup protein is conjugated to a target protein via an isopeptide bond between the carboxy-terminus of Pup and the epsilon-amino group of a lysine residue of the target protein.	tmpzr1t_l9r_go_relaxed.owl	Pup-protein conjugation|pupylation													biological_process											owl:Class	
GO:1901217	biolink:NamedThing	regulation of holin activity	Any process that modulates the frequency, rate or extent of holin activity.	tmpzr1t_l9r_go_relaxed.owl								bf	2012-08-06T10:47:38Z					biological_process											owl:Class	
GO:0098614	biolink:NamedThing	hydrogen selenide methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + hydrogen selenide => S-adenosyl-L-homocysteine + methaneselenol.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-2408536									molecular_function											owl:Class	
GO:0000162	biolink:NamedThing	tryptophan biosynthetic process	The chemical reactions and pathways resulting in the formation of tryptophan, the chiral amino acid 2-amino-3-(1H-indol-3-yl)propanoic acid; tryptophan is synthesized from chorismate via anthranilate.	tmpzr1t_l9r_go_relaxed.owl	tryptophan formation|tryptophan anabolism|aromatic amino acid family biosynthetic process, anthranilate pathway|tryptophan biosynthesis|tryptophan synthesis				MetaCyc:TRPSYN-PWY							GO:0009096		biological_process											owl:Class	
GO:0018817	biolink:NamedThing	2-oxo-hept-3-ene-1,7-dioate hydratase activity	Catalysis of the reaction: cis-2-oxohept-3-ene-1,7-dioate + H2O = 2,4-dihydroxy-hept-trans-2-ene-1,7-dioate.	tmpzr1t_l9r_go_relaxed.owl	2-oxo-hepta-3-ene-1,7-dioate hydratase activity|2-oxo-hepta-3-ene-1,7-dioic acid hydratase activity|HpaH				MetaCyc:HYDROXYHEPTA-DIENEDIOATE-HYDROXY-RXN|RHEA:42072|UM-BBD_reactionID:r0369									molecular_function											owl:Class	
GO:0003151	biolink:NamedThing	outflow tract morphogenesis	The process in which the anatomical structures of the outflow tract are generated and organized. The outflow tract is the portion of the heart through which blood flows into the arteries.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-09-22T07:59:24Z					biological_process											owl:Class	
GO:1903671	biolink:NamedThing	negative regulation of sprouting angiogenesis	Any process that stops, prevents or reduces the frequency, rate or extent of sprouting angiogenesis.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of sprouting angiogenesis|inhibition of sprouting angiogenesis|downregulation of sprouting angiogenesis|down regulation of sprouting angiogenesis							pga	2014-11-27T10:10:59Z					biological_process											owl:Class	
GO:0019101	biolink:NamedThing	female somatic sex determination	The determination of sex and sexual phenotypes in a female organism's soma.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0042733	biolink:NamedThing	embryonic digit morphogenesis	The process, occurring in the embryo, by which the anatomical structures of the digit are generated and organized. A digit is one of the terminal divisions of an appendage, such as a finger or toe.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1903422	biolink:NamedThing	negative regulation of synaptic vesicle recycling	Any process that stops, prevents or reduces the frequency, rate or extent of synaptic vesicle recycling.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of synaptic vesicle recycling|inhibition of synaptic vesicle recycling|down regulation of synaptic vesicle recycling|negative regulation of kiss-and-run synaptic vesicle recycling|inhibition of kiss-and-run synaptic vesicle recycling|down-regulation of kiss-and-run synaptic vesicle recycling|down regulation of kiss-and-stay synaptic vesicle recycling|downregulation of synaptic vesicle recycling|downregulation of kiss-and-run synaptic vesicle recycling|down-regulation of kiss-and-stay synaptic vesicle recycling|down regulation of kiss-and-run synaptic vesicle recycling|inhibition of kiss-and-stay synaptic vesicle recycling|negative regulation of kiss-and-stay synaptic vesicle recycling|downregulation of kiss-and-stay synaptic vesicle recycling					An example of this is mouse LRRK2 (Q5S006) in PMID:21307259 inferred from mutant phenotype		pad	2014-09-09T15:27:59Z					biological_process											owl:Class	
GO:0071405	biolink:NamedThing	cellular response to methanol	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methanol stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-12-14T02:54:44Z					biological_process											owl:Class	
GO:0045820	biolink:NamedThing	negative regulation of glycolytic process	Any process that stops, prevents, or reduces the frequency, rate or extent of glycolysis.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of glycolysis|down regulation of glycolysis|downregulation of glycolysis|inhibition of glycolysis													biological_process											owl:Class	
GO:0003162	biolink:NamedThing	atrioventricular node development	The process whose specific outcome is the progression of the atrioventricular (AV) node over time, from its formation to the mature structure. The AV node is part of the cardiac conduction system that controls the timing of ventricle contraction by receiving electrical signals from the sinoatrial (SA) node and relaying them to the His-Purkinje system.	tmpzr1t_l9r_go_relaxed.owl	AV node development							dph	2009-10-01T02:05:13Z					biological_process											owl:Class	
GO:0007538	biolink:NamedThing	primary sex determination	The sex determination process that results in the initial specification of sexual status of an individual organism.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0061645	biolink:NamedThing	endocytic patch	The part of the cell cortex consisting of  an aggregation of proteins that will give rise to an endocytic vesicle.	tmpzr1t_l9r_go_relaxed.owl								dph	2014-09-02T09:23:38Z					cellular_component											owl:Class	
GO:1904821	biolink:NamedThing	chloroplast disassembly	The disaggregation of a chloroplast into its constituent components.	tmpzr1t_l9r_go_relaxed.owl	chloroplast degradation					The disaggregation of a chloroplast into its constituent components.		lr	2015-11-19T00:41:18Z					biological_process											owl:Class	
GO:0051344	biolink:NamedThing	negative regulation of cyclic-nucleotide phosphodiesterase activity	Any process that stops or reduces the rate of cyclic nucleotide phosphodiesterase activity, the catalysis of the reaction: nucleotide 3',5'-cyclic phosphate + H2O = nucleotide 5'-phosphate.	tmpzr1t_l9r_go_relaxed.owl	phosphodiesterase inhibitor|3',5'-cyclic-AMP phosphodiesterase inhibitor|cAMP phosphodiesterase inhibitor|negative regulation of 3',5' cyclic nucleotide phosphodiesterase activity|3',5' cyclic nucleotide phosphodiesterase inhibitor|negative regulation of cGMP phosphodiesterase activity|negative regulation of 3',5'-cyclic-AMP phosphodiesterase activity|downregulation of cyclic nucleotide phosphodiesterase activity|down-regulation of cyclic nucleotide phosphodiesterase activity|negative regulation of cyclic nucleotide phosphodiesterase activity|down regulation of cyclic nucleotide phosphodiesterase activity|inhibition of cyclic nucleotide phosphodiesterase activity|negative regulation of cAMP phosphodiesterase activity													biological_process											owl:Class	
GO:0051342	biolink:NamedThing	regulation of cyclic-nucleotide phosphodiesterase activity	Any process that modulates the frequency, rate or extent of cyclic nucleotide phosphodiesterase activity, the catalysis of the reaction: nucleotide 3',5'-cyclic phosphate + H2O = nucleotide 5'-phosphate.	tmpzr1t_l9r_go_relaxed.owl	phosphodiesterase regulator|regulation of 3',5'-cyclic-AMP phosphodiesterase activity|regulation of cyclic nucleotide phosphodiesterase activity|3',5' cyclic nucleotide phosphodiesterase regulator|cAMP phosphodiesterase regulator|3',5'-cyclic-AMP phosphodiesterase regulator|regulation of cAMP phosphodiesterase activity|regulation of 3',5' cyclic nucleotide phosphodiesterase activity|regulation of cGMP phosphodiesterase activity													biological_process											owl:Class	
GO:0031777	biolink:NamedThing	type 1 melanin-concentrating hormone receptor binding	Binding to a type 1 melanin-concentrating hormone receptor.	tmpzr1t_l9r_go_relaxed.owl	type 1 melanin-concentrating hormone receptor ligand													molecular_function											owl:Class	
GO:0031776	biolink:NamedThing	melanin-concentrating hormone receptor binding	Binding to a melanin-concentrating hormone receptor.	tmpzr1t_l9r_go_relaxed.owl	melanin-concentrating hormone receptor ligand													molecular_function											owl:Class	
GO:0032618	biolink:NamedThing	interleukin-15 production	The appearance of interleukin-15 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	tmpzr1t_l9r_go_relaxed.owl	interleukin-15 secretion|interleukin-15 biosynthetic process|IL-15 production											GO:0072613|GO:0042233		biological_process											owl:Class	
GO:0046578	biolink:NamedThing	regulation of Ras protein signal transduction	Any process that modulates the frequency, rate or extent of Ras protein signal transduction.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1904143	biolink:NamedThing	positive regulation of carotenoid biosynthetic process	Any process that activates or increases the frequency, rate or extent of carotenoid biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of carotenoid biosynthetic process|positive regulation of carotenoid synthesis|positive regulation of carotenoid formation|up-regulation of carotenoid biosynthesis|up regulation of carotenoid anabolism|positive regulation of carotenoid biosynthesis|upregulation of carotenoid anabolism|up regulation of carotenoid biosynthesis|activation of carotenoid biosynthetic process|upregulation of carotenoid formation|activation of carotenoid synthesis|up-regulation of carotenoid anabolism|upregulation of carotenoid synthesis|up-regulation of carotenoid synthesis|positive regulation of carotenoid anabolism|up regulation of carotenoid formation|up regulation of carotenoid synthesis|upregulation of carotenoid biosynthetic process|activation of carotenoid anabolism|upregulation of carotenoid biosynthesis|up-regulation of carotenoid formation|activation of carotenoid biosynthesis|activation of carotenoid formation|up regulation of carotenoid biosynthetic process							tb	2015-04-13T19:39:19Z					biological_process											owl:Class	
GO:0060177	biolink:NamedThing	regulation of angiotensin metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving angiotensin.	tmpzr1t_l9r_go_relaxed.owl	regulation of angiotensin metabolism													biological_process											owl:Class	
GO:0014002	biolink:NamedThing	astrocyte development	The process aimed at the progression of an astrocyte over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. An astrocyte is the most abundant type of glial cell. Astrocytes provide support for neurons and regulate the environment in which they function.	tmpzr1t_l9r_go_relaxed.owl	astrocyte cell development													biological_process											owl:Class	
GO:0062100	biolink:NamedThing	positive regulation of programmed necrotic cell death	Any process that increases the frequency, rate or extent of programmed necrotic cell death.	tmpzr1t_l9r_go_relaxed.owl								dph	2018-11-29T15:08:35Z					biological_process											owl:Class	
GO:0031418	biolink:NamedThing	L-ascorbic acid binding	Binding to L-ascorbic acid, (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate; L-ascorbic acid is vitamin C and has co-factor and anti-oxidant activities in many species.	tmpzr1t_l9r_go_relaxed.owl	vitamin C binding|L-ascorbate binding													molecular_function											owl:Class	
GO:0007309	biolink:NamedThing	oocyte axis specification	The establishment, maintenance and elaboration of an axis in the oocyte. An example of this is found in Drosophila melanogaster.	tmpzr1t_l9r_go_relaxed.owl	oocyte axis determination											GO:0048111		biological_process											owl:Class	
GO:0032342	biolink:NamedThing	aldosterone biosynthetic process	The chemical reactions and pathways resulting in the formation of aldosterone, a corticosteroid hormone that is produced by the zona glomerulosa of the adrenal cortex and regulates salt (sodium and potassium) and water balance.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0002259	biolink:NamedThing	endothelial cell activation within high endothelial venule involved in immune response	A change in the morphology or behavior of an endothelial cell within a high endothelial venule resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response.	tmpzr1t_l9r_go_relaxed.owl	endothelial cell activation within high endothelial venule during immune response													biological_process											owl:Class	
GO:0002264	biolink:NamedThing	endothelial cell activation involved in immune response	A change in the morphology or behavior of an endothelial cell resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response.	tmpzr1t_l9r_go_relaxed.owl	endothelial cell activation during immune response													biological_process											owl:Class	
GO:0030194	biolink:NamedThing	positive regulation of blood coagulation	Any process that activates or increases the frequency, rate or extent of blood coagulation.	tmpzr1t_l9r_go_relaxed.owl	up regulation of blood coagulation|stimulation of blood coagulation|activation of blood coagulation|upregulation of blood coagulation|up-regulation of blood coagulation													biological_process											owl:Class	
GO:0071966	biolink:NamedThing	fungal-type cell wall polysaccharide metabolic process	The chemical reactions and pathways involving the polysaccharides which make up the fungal-type cell wall.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-10-14T11:56:47Z					biological_process											owl:Class	
GO:0075260	biolink:NamedThing	regulation of spore-bearing organ development	Any process that modulates the frequency, rate or extent of spore-bearing organ development, a process in which hyphae grow into special aggregates called fruiting bodies that produce new spores.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1904078	biolink:NamedThing	positive regulation of estrogen biosynthetic process	Any process that activates or increases the frequency, rate or extent of estrogen biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of oestrogen biosynthesis|up-regulation of estrogen formation|up regulation of estrogen biosynthesis|up regulation of estrogen biosynthetic process|upregulation of estrogen biosynthesis|positive regulation of estrogen biosynthesis|upregulation of oestrogen biosynthetic process|up-regulation of estrogen synthesis|up regulation of estrogen synthesis|positive regulation of oestrogen biosynthesis|up-regulation of estrogen anabolism|upregulation of estrogen biosynthetic process|activation of oestrogen biosynthetic process|positive regulation of estrogen anabolism|upregulation of estrogen anabolism|activation of estrogen biosynthesis|upregulation of oestrogen biosynthesis|activation of estrogen biosynthetic process|activation of oestrogen biosynthesis|upregulation of estrogen synthesis|positive regulation of estrogen synthesis|activation of estrogen anabolism|positive regulation of estrogen formation|up-regulation of oestrogen biosynthetic process|activation of estrogen formation|up-regulation of estrogen biosynthetic process|upregulation of estrogen formation|activation of estrogen synthesis|up regulation of estrogen formation|positive regulation of oestrogen biosynthetic process|up-regulation of estrogen biosynthesis|up regulation of oestrogen biosynthesis|up regulation of oestrogen biosynthetic process|up regulation of estrogen anabolism							tb	2015-03-20T16:56:26Z					biological_process											owl:Class	
GO:0046856	biolink:NamedThing	phosphatidylinositol dephosphorylation	The process of removing one or more phosphate groups from a phosphatidylinositol.	tmpzr1t_l9r_go_relaxed.owl	PtdInsP dephosphorylation|phosphatidylinositol phosphate dephosphorylation|PIP catabolism|phosphatidylinositol phosphate catabolic process|PtdInsP catabolism|phosphoinositide dephosphorylation											GO:0046840		biological_process											owl:Class	
GO:1903669	biolink:NamedThing	positive regulation of chemorepellent activity	Any process that activates or increases the frequency, rate or extent of chemorepellent activity.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of chemorepellant activity|up-regulation of chemorepellent activity|activation of chemorepellent activity|activation of chemorepellant activity|upregulation of chemorepellent activity|up regulation of chemorepellent activity|up regulation of chemorepellant activity|upregulation of chemorepellant activity|up-regulation of chemorepellant activity							pf	2014-11-26T23:58:50Z					biological_process											owl:Class	
GO:0033055	biolink:NamedThing	D-arginine metabolic process	The chemical reactions and pathways involving D-arginine, the D-enantiomer of the amino acid arginine, i.e. (2R)-2-amino-5-(carbamimidamido)pentanoic acid.	tmpzr1t_l9r_go_relaxed.owl	D-arginine metabolism													biological_process											owl:Class	
GO:0006525	biolink:NamedThing	arginine metabolic process	The chemical reactions and pathways involving arginine, 2-amino-5-(carbamimidamido)pentanoic acid.	tmpzr1t_l9r_go_relaxed.owl	arginine metabolism				Wikipedia:Arginine									biological_process											owl:Class	
GO:1904211	biolink:NamedThing	membrane protein proteolysis involved in retrograde protein transport, ER to cytosol	Any membrane protein proteolysis that is involved in retrograde protein transport, ER to cytosol.	tmpzr1t_l9r_go_relaxed.owl	intramembrane proteolysis involved in ERAD|membrane protein proteolysis involved in retrograde protein transport, endoplasmic reticulum to cytosol|intramembrane cleavage of ERAD substrate|membrane protein proteolysis involved in protein dislocation from ER|membrane protein proteolysis involved in protein retrotranslocation, ER to cytosol							bf	2015-05-14T15:26:44Z					biological_process											owl:Class	
GO:0097035	biolink:NamedThing	regulation of membrane lipid distribution	Any process that modulates the proportions or spatial arrangement of lipids in a cellular membrane.	tmpzr1t_l9r_go_relaxed.owl								pr	2011-04-08T02:01:19Z					biological_process											owl:Class	
GO:1905413	biolink:NamedThing	regulation of dense core granule exocytosis	Any process that modulates the frequency, rate or extent of dense core granule exocytosis.	tmpzr1t_l9r_go_relaxed.owl	regulation of dense core vesicle exocytosis							bf	2016-08-31T08:02:21Z					biological_process											owl:Class	
GO:0090659	biolink:NamedThing	walking behavior	The behavior of an organism relating to the progression of that organism along the ground by the process of lifting and setting down each leg.	tmpzr1t_l9r_go_relaxed.owl	locomotor gait pattern							tb	2015-08-27T16:34:28Z					biological_process											owl:Class	
GO:0000478	biolink:NamedThing	endonucleolytic cleavage involved in rRNA processing	Any endonucleolytic cleavage involved in the conversion of a primary ribosomal RNA (rRNA) transcript into a mature rRNA molecule. Some endonucleolytic cleavages produce the mature end, while others are a step in the process of generating the mature end from the pre-rRNA.	tmpzr1t_l9r_go_relaxed.owl	endonucleolytic cleavage during rRNA processing													biological_process											owl:Class	
GO:2000697	biolink:NamedThing	negative regulation of epithelial cell differentiation involved in kidney development	Any process that stops, prevents or reduces the frequency, rate or extent of epithelial cell differentiation involved in kidney development.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-05-16T04:23:55Z					biological_process											owl:Class	
GO:0033255	biolink:NamedThing	SAS acetyltransferase complex	A protein complex that possesses histone acetyltransferase activity and links histone acetylation to the assembly of transcriptionally silent chromatin. In vitro, the complex acetylates lysine 16 of histone H4 and lysine 14 of histone H3, although the latter may not be relevant in vivo. The complex contains a catalytic subunit and at least two other subunits; in Saccharomyces, the catalytic subunit is Sas2p and additional subunits are Sas4p and Sas5p.	tmpzr1t_l9r_go_relaxed.owl	SAS-I complex													cellular_component											owl:Class	
GO:0032777	biolink:NamedThing	Piccolo NuA4 histone acetyltransferase complex	A heterotrimeric H4/H2A histone acetyltransferase complex with a substrate preference of chromatin over free histones. It contains a subset of the proteins found in the larger NuA4 histone acetyltransferase complex; for example, the S. cerevisiae complex contains Esa1p, Yng2p, and Epl1p.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:1903529	biolink:NamedThing	negative regulation of dCDP biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of dCDP biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	downregulation of dCDP biosynthesis|down-regulation of dCDP biosynthetic process|inhibition of dCDP synthesis|downregulation of dCDP anabolism|inhibition of dCDP biosynthetic process|down-regulation of dCDP anabolism|negative regulation of dCDP synthesis|down regulation of dCDP synthesis|down regulation of dCDP formation|down regulation of dCDP biosynthesis|inhibition of dCDP formation|down regulation of dCDP anabolism|downregulation of dCDP formation|negative regulation of dCDP biosynthesis|inhibition of dCDP biosynthesis|down-regulation of dCDP biosynthesis|down regulation of dCDP biosynthetic process|downregulation of dCDP biosynthetic process|inhibition of dCDP anabolism|negative regulation of dCDP anabolism|down-regulation of dCDP synthesis|negative regulation of dCDP formation|down-regulation of dCDP formation|downregulation of dCDP synthesis							al	2014-10-07T15:01:27Z					biological_process											owl:Class	
GO:1900398	biolink:NamedThing	negative regulation of pyrimidine nucleotide biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of pyrimidine nucleotide biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	down regulation of pyrimidine nucleotide biosynthetic process|negative regulation of pyrimidine nucleotide biosynthesis|downregulation of pyrimidine nucleotide formation|down regulation of pyrimidine nucleotide formation|downregulation of pyrimidine nucleotide anabolism|negative regulation of pyrimidine nucleotide anabolism|downregulation of pyrimidine nucleotide synthesis|down-regulation of pyrimidine nucleotide formation|down-regulation of pyrimidine nucleotide synthesis|down regulation of pyrimidine nucleotide synthesis|down-regulation of pyrimidine nucleotide biosynthesis|downregulation of pyrimidine nucleotide biosynthesis|down-regulation of pyrimidine nucleotide anabolism|inhibition of pyrimidine nucleotide formation|inhibition of pyrimidine nucleotide anabolism|down regulation of pyrimidine nucleotide biosynthesis|downregulation of pyrimidine nucleotide biosynthetic process|inhibition of pyrimidine nucleotide biosynthetic process|inhibition of pyrimidine nucleotide biosynthesis|down-regulation of pyrimidine nucleotide biosynthetic process|inhibition of pyrimidine nucleotide synthesis|down regulation of pyrimidine nucleotide anabolism|negative regulation of pyrimidine nucleotide formation|negative regulation of pyrimidine nucleotide synthesis							jh	2012-04-19T01:05:41Z					biological_process											owl:Class	
GO:0046895	biolink:NamedThing	N-terminal peptidyl-isoleucine methylation	The methylation of the N-terminal isoleucine of proteins to form the derivative N-methyl-L-isoleucine.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0336									biological_process											owl:Class	
GO:1903396	biolink:NamedThing	negative regulation of secondary cell septum biogenesis	Any process that stops, prevents or reduces the frequency, rate or extent of secondary cell septum biogenesis.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of secondary cell septum biogenesis|inhibition of secondary cell septum biogenesis|down regulation of secondary cell septum biogenesis|downregulation of secondary cell septum biogenesis							di	2014-08-29T21:42:26Z					biological_process											owl:Class	
GO:0047606	biolink:NamedThing	hydroxynitrilase activity	Catalysis of the reaction: a hydroxynitrile = cyanide + an aldehyde or ketone.	tmpzr1t_l9r_go_relaxed.owl	(S)-acetone-cyanohydrin lyase activity|acetone-cyanohydrin lyase activity|hydroxynitrile lyase activity|acetone-cyanohydrin acetone-lyase (cyanide-forming)|acetone-cyanohydrin acetone-lyase activity|oxynitrilase activity|alpha-hydroxynitrile lyase activity|2-hydroxyisobutyronitrile acetone-lyase (cyanide-forming)|acetone-cyanhydrin lyase activity|2-hydroxyisobutyronitrile acetone-lyase activity				EC:4.1.2.47|MetaCyc:ACETONE-CYANHYDRIN-LYASE-RXN							GO:0046991		molecular_function											owl:Class	
GO:0034144	biolink:NamedThing	negative regulation of toll-like receptor 4 signaling pathway	Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 4 signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of TLR4 signaling pathway|negative regulation of toll-like receptor 4 signalling pathway													biological_process											owl:Class	
GO:0032748	biolink:NamedThing	positive regulation of interleukin-24 production	Any process that activates or increases the frequency, rate, or extent of interleukin-24 production.	tmpzr1t_l9r_go_relaxed.owl	stimulation of interleukin-24 production|positive regulation of IL-24 production|positive regulation of interleukin-24 biosynthetic process|activation of interleukin-24 production|upregulation of interleukin-24 production|up regulation of interleukin-24 production|up-regulation of interleukin-24 production											GO:0045536		biological_process											owl:Class	
GO:0030335	biolink:NamedThing	positive regulation of cell migration	Any process that activates or increases the frequency, rate or extent of cell migration.	tmpzr1t_l9r_go_relaxed.owl	activation of cell migration|stimulation of cell migration|up-regulation of cell migration|up regulation of cell migration|upregulation of cell migration													biological_process											owl:Class	
GO:1901332	biolink:NamedThing	negative regulation of lateral root development	Any process that stops, prevents or reduces the frequency, rate or extent of lateral root development.	tmpzr1t_l9r_go_relaxed.owl	downregulation of lateral root development|down-regulation of lateral root development|down regulation of lateral root development|inhibition of lateral root development							tb	2012-09-01T00:58:37Z					biological_process											owl:Class	
GO:0005359	biolink:NamedThing	low-affinity glucose:proton symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucose(out) + H(out)+ = glucose(in) + H(in)+. In low-affinity transport the transporter is able to bind the solute only if it is present at very high concentrations. Symporter activity enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported together in the same direction in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy.	tmpzr1t_l9r_go_relaxed.owl	low-affinity hydrogen:glucose symporter activity|low-affinity hydrogen:glucose transporter activity|low-affinity hydrogen/glucose transporter activity													molecular_function											owl:Class	
GO:0070390	biolink:NamedThing	transcription export complex 2	A protein complex that couples SAGA-dependent gene expression to mRNA export at the inner side of the nuclear pore complex (NPC). The TREX-2 complex is tethered to the inner side of the NPC via the nucleoporins Nup1 and Nup60; in S. cerevisiae it contains Sac3p, Thp1p, Sem1, Sus1p and Cdc31p.	tmpzr1t_l9r_go_relaxed.owl	TREX-2 complex|Sac3-Thp1-Sus1-Sem1-Cdc31 complex													cellular_component											owl:Class	
GO:0036259	biolink:NamedThing	aerobic raffinose catabolic process	The chemical reactions and pathways resulting in the breakdown of raffinose that occur in the presence of oxygen.	tmpzr1t_l9r_go_relaxed.owl	aerobic raffinose breakdown|aerobic raffinose catabolism|aerobic raffinose degradation							bf	2012-06-15T01:14:51Z					biological_process											owl:Class	
GO:0034484	biolink:NamedThing	raffinose catabolic process	The chemical reactions and pathways resulting in the breakdown of raffinose, the trisaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside.	tmpzr1t_l9r_go_relaxed.owl	raffinose degradation|raffinose catabolism|raffinose breakdown													biological_process											owl:Class	
GO:1902822	biolink:NamedThing	regulation of late endosome to lysosome transport	Any process that modulates the frequency, rate or extent of late endosome to lysosome transport.	tmpzr1t_l9r_go_relaxed.owl	regulation of prevacuolar compartment to lysosome transport							pad	2014-03-31T10:08:38Z					biological_process											owl:Class	
GO:0009243	biolink:NamedThing	O antigen biosynthetic process	The chemical reactions and pathways resulting in the formation of the O side chain of a lipopolysaccharide, which determines the antigenic specificity of the organism. It is made up of about 50 repeating units of a branched tetrasaccharide.	tmpzr1t_l9r_go_relaxed.owl	O antigen synthesis|O antigen biosynthesis|O antigen anabolism|O antigen formation													biological_process											owl:Class	
GO:0046402	biolink:NamedThing	O antigen metabolic process	The chemical reactions and pathways involving the O side chain of a lipopolysaccharide, which determines the antigenic specificity of the organism. It is made up of about 50 repeating units of a branched tetrasaccharide.	tmpzr1t_l9r_go_relaxed.owl	O antigen metabolism													biological_process											owl:Class	
GO:0023029	biolink:NamedThing	MHC class Ib protein binding	Binding to a major histocompatibility complex class Ib molecules.	tmpzr1t_l9r_go_relaxed.owl									2010-02-16T09:30:50Z					molecular_function											owl:Class	
GO:0052897	biolink:NamedThing	N8-acetylspermidine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity	Catalysis of the reaction: H(2)O + N(8)-acetylspermidine + O(2) = 1,3-diaminopropane + 4-acetamidobutanal + H(2)O(2).	tmpzr1t_l9r_go_relaxed.owl	N(8)-acetylspermidine oxidase (propane-1,3-diamine-forming) activity				KEGG_REACTION:R09075|MetaCyc:RXN-10463|RHEA:25972|EC:1.5.3.15									molecular_function											owl:Class	
GO:0032499	biolink:NamedThing	detection of peptidoglycan	The series of events in which a peptidoglycan stimulus is received by a cell and converted into a molecular signal. Peptidoglycan is a bacterial cell wall macromolecule.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1905081	biolink:NamedThing	positive regulation of cerebellar neuron development	Any process that activates or increases the frequency, rate or extent of cerebellar neuron development.	tmpzr1t_l9r_go_relaxed.owl	upregulation of cerebellar neuron development|activation of cerebellar neuron development|up-regulation of cerebellar neuron development|up regulation of cerebellar neuron development							hjd	2016-03-24T19:45:35Z					biological_process											owl:Class	
GO:0050432	biolink:NamedThing	catecholamine secretion	The regulated release of catecholamines by a cell. The catecholamines are a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0046127	biolink:NamedThing	pyrimidine deoxyribonucleoside catabolic process	The chemical reactions and pathways resulting in the breakdown of any one of a family of organic molecules consisting of a pyrimidine base covalently bonded to a sugar deoxyribose (a deoxyribonucleoside).	tmpzr1t_l9r_go_relaxed.owl	pyrimidine deoxyribonucleoside catabolism|pyrimidine deoxyribonucleoside degradation|pyrimidine deoxyribonucleoside breakdown													biological_process											owl:Class	
GO:0051318	biolink:NamedThing	G1 phase	The cell cycle 'gap' phase which is the interval between the completion of DNA segregation (usually by mitosis or meiosis) and the beginning of DNA synthesis.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:G1_phase	Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).								biological_process											owl:Class	
GO:1905472	biolink:NamedThing	negative regulation of histone H3-K79 dimethylation	Any process that stops, prevents or reduces the frequency, rate or extent of histone H3-K79 dimethylation.	tmpzr1t_l9r_go_relaxed.owl	down regulation of histone H3-K79 dimethylation|down regulation of histone H3 K79 dimethylation|down-regulation of histone H3 K79 dimethylation|down regulation of histone lysine H3 K79 dimethylation|negative regulation of histone H3 K79 dimethylation|downregulation of histone H3-K79 dimethylation|down-regulation of histone H3-K79 dimethylation|downregulation of histone H3 K79 dimethylation|down-regulation of histone lysine H3 K79 dimethylation|negative regulation of histone lysine H3 K79 dimethylation|inhibition of histone lysine H3 K79 dimethylation|inhibition of histone H3 K79 dimethylation|downregulation of histone lysine H3 K79 dimethylation|inhibition of histone H3-K79 dimethylation							hbye	2016-09-21T15:27:10Z					biological_process											owl:Class	
GO:0046103	biolink:NamedThing	inosine biosynthetic process	The chemical reactions and pathways resulting in the formation of inosine, hypoxanthine riboside, a nucleoside found free but not in combination in nucleic acids except in the anticodons of some tRNAs.	tmpzr1t_l9r_go_relaxed.owl	inosine synthesis|inosine anabolism|inosine formation|inosine biosynthesis													biological_process											owl:Class	
GO:0046128	biolink:NamedThing	purine ribonucleoside metabolic process	The chemical reactions and pathways involving any ribonucleoside, a nucleoside in which purine base is linked to a ribose (beta-D-ribofuranose) molecule.	tmpzr1t_l9r_go_relaxed.owl	purine ribonucleoside metabolism													biological_process											owl:Class	
GO:0006867	biolink:NamedThing	asparagine transport	The directed movement of asparagine, alpha-aminosuccinamic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	L-asparagine transport													biological_process											owl:Class	
GO:0015968	biolink:NamedThing	stringent response	A specific global change in the metabolism of a bacterial cell (the downregulation of nucleic acid and protein synthesis, and the simultaneous upregulation of protein degradation and amino acid synthesis) as a result of starvation.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Stringent_response									biological_process											owl:Class	
GO:2000387	biolink:NamedThing	regulation of antral ovarian follicle growth	Any process that modulates the frequency, rate or extent of antral ovarian follicle growth.	tmpzr1t_l9r_go_relaxed.owl								yaf	2011-02-16T04:53:43Z					biological_process											owl:Class	
GO:0005956	biolink:NamedThing	protein kinase CK2 complex	A protein complex that possesses protein serine/threonine kinase activity, and contains two catalytic alpha subunits and two regulatory beta subunits. Protein kinase CK2 complexes are found in nearly every subcellular compartment, and can phosphorylate many protein substrates in addition to casein.	tmpzr1t_l9r_go_relaxed.owl	casein kinase II complex					Note that this term represents a location and not a function; the activity possessed by this complex is mentioned in the definition for the purpose of describing and distinguishing the complex.								cellular_component											owl:Class	
GO:1903688	biolink:NamedThing	positive regulation of border follicle cell migration	Any process that activates or increases the frequency, rate or extent of border follicle cell migration.	tmpzr1t_l9r_go_relaxed.owl	activation of border follicle cell migration							als	2014-12-01T13:41:19Z					biological_process											owl:Class	
GO:1900810	biolink:NamedThing	helvolic acid metabolic process	The chemical reactions and pathways involving helvolic acid.	tmpzr1t_l9r_go_relaxed.owl	Fumigacin metabolism|Fumigacin metabolic process|helvolic acid metabolism							di	2012-06-04T10:02:28Z					biological_process											owl:Class	
GO:0010390	biolink:NamedThing	histone monoubiquitination	The modification of histones by addition of a single ubiquitin group.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0006513	biolink:NamedThing	protein monoubiquitination	Addition of a single ubiquitin group to a protein.	tmpzr1t_l9r_go_relaxed.owl	protein monoubiquitinylation|protein monoubiquitylation													biological_process											owl:Class	
GO:0003285	biolink:NamedThing	septum secundum development	The progression of the septum secundum over time, from its initial formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-10-20T10:21:13Z					biological_process											owl:Class	
GO:0042171	biolink:NamedThing	lysophosphatidic acid acyltransferase activity	Catalysis of the transfer of acyl groups from an acyl-CoA to lysophosphatidic acid to form phosphatidic acid.	tmpzr1t_l9r_go_relaxed.owl	LPAAT activity													molecular_function											owl:Class	
GO:0071617	biolink:NamedThing	lysophospholipid acyltransferase activity	Catalysis of the transfer of acyl groups from an acyl-CoA to a lysophospholipid.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-02-08T04:53:37Z					molecular_function											owl:Class	
GO:0060117	biolink:NamedThing	auditory receptor cell development	The process whose specific outcome is the progression of an auditory receptor cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate.	tmpzr1t_l9r_go_relaxed.owl	auditory hair cell development													biological_process											owl:Class	
GO:0060119	biolink:NamedThing	inner ear receptor cell development	The process whose specific outcome is the progression of an inner ear receptor cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate.	tmpzr1t_l9r_go_relaxed.owl	inner ear hair cell development													biological_process											owl:Class	
GO:0035094	biolink:NamedThing	response to nicotine	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nicotine stimulus.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1901340	biolink:NamedThing	negative regulation of store-operated calcium channel activity	Any process that stops, prevents or reduces the frequency, rate or extent of store-operated calcium channel activity.	tmpzr1t_l9r_go_relaxed.owl	down regulation of store-operated calcium channel activity|down-regulation of store-operated calcium channel activity|inhibition of store-operated calcium channel activity|downregulation of store-operated calcium channel activity							pr	2012-09-03T14:24:21Z					biological_process											owl:Class	
GO:1901020	biolink:NamedThing	negative regulation of calcium ion transmembrane transporter activity	Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion transmembrane transporter activity.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of calcium ion transmembrane transporter activity|inhibition of calcium ion transmembrane transporter activity|downregulation of calcium ion transmembrane transporter activity|down regulation of calcium ion transmembrane transporter activity							rl	2012-06-15T07:54:32Z					biological_process											owl:Class	
GO:2000791	biolink:NamedThing	negative regulation of mesenchymal cell proliferation involved in lung development	Any process that stops, prevents or reduces the frequency, rate or extent of mesenchymal cell proliferation involved in lung development.	tmpzr1t_l9r_go_relaxed.owl								pr	2011-06-24T01:53:53Z					biological_process											owl:Class	
GO:0008809	biolink:NamedThing	carnitine racemase activity	Catalysis of the reaction: D-carnitine = L-carnitine.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:CARNRACE-RXN									molecular_function											owl:Class	
GO:0003177	biolink:NamedThing	pulmonary valve development	The progression of the pulmonary valve over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-10-08T11:19:44Z					biological_process											owl:Class	
GO:1905314	biolink:NamedThing	semi-lunar valve development	The process whose specific outcome is the progression of a semi-lunar valve over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl	semilunar valves development|semilunar valve development							rl	2016-07-11T17:50:44Z					biological_process											owl:Class	
GO:0097526	biolink:NamedThing	spliceosomal tri-snRNP complex	A spliceosomal snRNP complex that is formed by the association of the U4/U6 (or U4atac/U6atac) snRNP with the U5 snRNP.	tmpzr1t_l9r_go_relaxed.owl								pr	2013-10-18T15:58:47Z					cellular_component											owl:Class	
GO:1902093	biolink:NamedThing	positive regulation of flagellated sperm motility	Any process that activates or increases the frequency, rate or extent of flagellated sperm motility.	tmpzr1t_l9r_go_relaxed.owl	upregulation of sperm movement|up regulation of sperm movement|upregulation of sperm motility|activation of sperm motility|activation of sperm movement|up-regulation of sperm motility|up regulation of sperm motility|positive regulation of sperm movement|up-regulation of sperm movement|positive regulation of sperm motility							bf	2013-04-29T09:15:25Z					biological_process											owl:Class	
GO:0051582	biolink:NamedThing	positive regulation of neurotransmitter uptake	Any process that activates or increases the frequency, rate or extent of the directed movement of a neurotransmitter into a neuron or glial cell.	tmpzr1t_l9r_go_relaxed.owl	up regulation of neurotransmitter uptake|activation of neurotransmitter uptake|stimulation of neurotransmitter uptake|up-regulation of neurotransmitter uptake|positive regulation of neurotransmitter import|upregulation of neurotransmitter uptake													biological_process											owl:Class	
GO:1904962	biolink:NamedThing	plastid to vacuole vesicle-mediated transport	The vesicle-mediated and directed movement of substances from plastid to vacuole.	tmpzr1t_l9r_go_relaxed.owl	plastid to vacuolar carboxypeptidase Y vesicle-mediated transport							tb	2016-02-10T00:14:48Z					biological_process											owl:Class	
GO:1900738	biolink:NamedThing	positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway	Any process that activates or increases the frequency, rate or extent of phospholipase C-activating G protein-coupled receptor signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	up regulation of G protein signaling, coupled to IP3 second messenger (phospholipase C activating)|up-regulation of G protein signaling, coupled to IP3 second messenger (phospholipase C activating)|up-regulation of phospholipase C-activating G-protein coupled receptor signaling pathway|up regulation of G-protein coupled receptor signaling pathway coupled to IP3 second messenger|positive regulation of PLC-activating GPCR signaling pathway|positive regulation of G protein signaling, coupled to IP3 second messenger (phospholipase C activating)|up-regulation of G-protein signalling, coupled to IP3 second messenger (phospholipase C activating)|up regulation of G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)|positive regulation of G-protein coupled receptor signaling pathway coupled to IP3 second messenger|up-regulation of PLC-activating GPCR signaling pathway|activation of activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger|positive regulation of G-protein signalling, coupled to IP3 second messenger (phospholipase C activating)|activation of PLC-activating GPCR signaling pathway|up-regulation of G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)|activation of phospholipase C-activating dopamine receptor signaling pathway|activation of G protein signalling, coupled to IP3 second messenger (phospholipase C activating)|positive regulation of G protein signalling, coupled to IP3 second messenger (phospholipase C activating)|up-regulation of phospholipase C-activating dopamine receptor signaling pathway|upregulation of PLC-activating GPCR signaling pathway|activation of G-protein coupled receptor signaling pathway coupled to IP3 second messenger|activation of G protein signaling, coupled to IP3 second messenger (phospholipase C activating)|up-regulation of activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger|positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway|upregulation of G protein signalling, coupled to IP3 second messenger (phospholipase C activating)|upregulation of activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger|upregulation of G-protein coupled receptor signaling pathway coupled to IP3 second messenger|up regulation of phospholipase C-activating G-protein coupled receptor signaling pathway|activation of G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)|up regulation of phospholipase C-activating dopamine receptor signaling pathway|upregulation of G-protein signalling, coupled to IP3 second messenger (phospholipase C activating)|up regulation of PLC-activating GPCR signaling pathway|upregulation of phospholipase C-activating G-protein coupled receptor signaling pathway|upregulation of G protein signaling, coupled to IP3 second messenger (phospholipase C activating)|activation of phospholipase C-activating G-protein coupled receptor signaling pathway|positive regulation of G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)|activation of G-protein signalling, coupled to IP3 second messenger (phospholipase C activating)|up-regulation of G-protein coupled receptor signaling pathway coupled to IP3 second messenger|up regulation of G-protein signalling, coupled to IP3 second messenger (phospholipase C activating)|up regulation of activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger|up regulation of G protein signalling, coupled to IP3 second messenger (phospholipase C activating)|upregulation of G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)|upregulation of phospholipase C-activating dopamine receptor signaling pathway|positive regulation of phospholipase C-activating dopamine receptor signaling pathway|positive regulation of activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger|up-regulation of G protein signalling, coupled to IP3 second messenger (phospholipase C activating)							rl	2012-05-28T10:07:56Z					biological_process											owl:Class	
GO:0045752	biolink:NamedThing	positive regulation of Toll signaling pathway	Any process that activates or increases the frequency, rate or extent of the Tl signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	activation of Toll signaling pathway|stimulation of Toll signaling pathway|positive regulation of Tl signaling pathway|up-regulation of Toll signaling pathway|up regulation of Toll signaling pathway|upregulation of Toll signaling pathway|positive regulation of Tl signalling pathway													biological_process											owl:Class	
GO:0008592	biolink:NamedThing	regulation of Toll signaling pathway	Any process that modulates the frequency, rate or extent of the Tl signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	regulation of Tl signalling pathway|regulation of Toll signalling pathway|regulation of Tl signaling pathway													biological_process											owl:Class	
GO:0060125	biolink:NamedThing	negative regulation of growth hormone secretion	Any process that decreases or stops the frequency, rate or extent of the regulated release of growth hormone from a cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1905421	biolink:NamedThing	regulation of plant organ morphogenesis	Any process that modulates the frequency, rate or extent of plant organ morphogenesis.	tmpzr1t_l9r_go_relaxed.owl								tb	2016-09-06T23:00:14Z					biological_process											owl:Class	
GO:0045488	biolink:NamedThing	pectin metabolic process	The chemical reactions and pathways involving pectin, a group of galacturonic acid-containing, water-soluble colloidal carbohydrates of high molecular weight and of net negative charge.	tmpzr1t_l9r_go_relaxed.owl	pectin metabolism													biological_process											owl:Class	
GO:0036254	biolink:NamedThing	cellular response to amiloride	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amiloride stimulus.	tmpzr1t_l9r_go_relaxed.owl								bf	2012-06-15T01:06:16Z					biological_process											owl:Class	
GO:1905579	biolink:NamedThing	negative regulation of ERBB3 signaling pathway	Any process that stops, prevents or reduces the frequency, rate or extent of ERBB3 signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	down regulation of ERBB3 signaling pathway|down-regulation of ERBB3 signaling pathway|down regulation of receptor tyrosine-protein kinase erbB-3 signaling pathway|negative regulation of ERBB3 signalling pathway|inhibition of ERBB3 signalling pathway|downregulation of ERBB3 signaling pathway|downregulation of receptor tyrosine-protein kinase erbB-3 signaling pathway|inhibition of receptor tyrosine-protein kinase erbB-3 signaling pathway|negative regulation of HER3 signaling pathway|downregulation of HER3 signaling pathway|downregulation of ERBB3 signalling pathway|inhibition of HER3 signaling pathway|negative regulation of receptor tyrosine-protein kinase erbB-3 signaling pathway|down regulation of ERBB3 signalling pathway|down-regulation of receptor tyrosine-protein kinase erbB-3 signaling pathway|inhibition of ERBB3 signaling pathway|down regulation of HER3 signaling pathway|down-regulation of HER3 signaling pathway|down-regulation of ERBB3 signalling pathway							als	2016-10-19T11:47:03Z					biological_process											owl:Class	
GO:0030809	biolink:NamedThing	negative regulation of nucleotide biosynthetic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nucleotides.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of nucleotide synthesis|inhibition of nucleotide biosynthetic process|negative regulation of nucleotide anabolism|negative regulation of nucleotide biosynthesis|down-regulation of nucleotide biosynthetic process|downregulation of nucleotide biosynthetic process|negative regulation of nucleotide formation|down regulation of nucleotide biosynthetic process													biological_process											owl:Class	
GO:0045980	biolink:NamedThing	negative regulation of nucleotide metabolic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving nucleotides.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of nucleotide metabolism|down regulation of nucleotide metabolic process|down-regulation of nucleotide metabolic process|inhibition of nucleotide metabolic process|downregulation of nucleotide metabolic process													biological_process											owl:Class	
GO:0060142	biolink:NamedThing	regulation of syncytium formation by plasma membrane fusion	Any process that modulates the frequency, rate or extent of the formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0035287	biolink:NamedThing	head segmentation	Partitioning the insect head anlage into a fixed number of segmental units. The number of segments composing the insect head has long been a subject of debate, but it is generally agreed that there are 6 or 7 segments. From anterior to posterior the head segments are the procephalic segments (labral, (ocular), antennal and intercalary) and the gnathal segments (mandibular, maxillary and labial).	tmpzr1t_l9r_go_relaxed.owl						See also the fly_anatomy.ontology term 'head segment ; FBbt:00000006' and its children.								biological_process											owl:Class	
GO:0097229	biolink:NamedThing	sperm end piece	The short tip of the sperm flagellum, adjacent to the sperm principal piece and furthest from the sperm head, which contains only the axoneme surrounded by the plasma membrane.	tmpzr1t_l9r_go_relaxed.owl								pr	2012-01-25T01:29:04Z					cellular_component											owl:Class	
GO:0015100	biolink:NamedThing	vanadium ion transmembrane transporter activity	Enables the transfer of vanadium (V) ions from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0047292	biolink:NamedThing	trihydroxypterocarpan dimethylallyltransferase activity	Catalysis of the reaction: (6AS,11AS)-3,6A,9-trihydroxypterocarpan + dimethylallyl-pyrophosphate = glyceollin + diphosphate.	tmpzr1t_l9r_go_relaxed.owl	dimethylallyl-diphosphate:(6aS,11aS)-3,6a,9-trihydroxypterocarpan dimethyltransferase activity|dimethylallyl-diphosphate:(6aS,11aS)-3,6a,9-trihydroxypterocarpan dimethylallyltransferase activity|dimethylallylpyrophosphate:trihydroxypterocarpan dimethylallyl transferase activity|dimethylallylpyrophosphate:3,6a,9-trihydroxypterocarpan dimethylallyltransferase activity				MetaCyc:2.5.1.36-RXN|EC:2.5.1.36									molecular_function											owl:Class	
GO:0010310	biolink:NamedThing	regulation of hydrogen peroxide metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving hydrogen peroxide.	tmpzr1t_l9r_go_relaxed.owl	regulation of hydrogen peroxide metabolism													biological_process											owl:Class	
GO:0071794	biolink:NamedThing	CAP-Gly domain binding	Binding to a CAP-Gly domain of a protein. The CAP_Gly domain is a conserved, glycine-rich domain of about 42 residues found in some cytoskeleton-associated proteins, and features a novel protein fold containing three beta-sheets.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-09-02T02:02:53Z					molecular_function											owl:Class	
GO:0002435	biolink:NamedThing	immune complex clearance by erythrocytes	The process of immune complex clearance by erythrocytes. The process often starts with binding of complement receptor 1 (CR1) on the surface of erythrocytes to a complement coated immune complex. The complex bound to erythrocyte CR1 is then transported to the liver or spleen where it is presented to phagocytes. The process ends when the complex is removed from CR1, allowing the erythrocyte to return to general circulation.	tmpzr1t_l9r_go_relaxed.owl	immune complex clearance by RBCs|immune complex clearance by red blood cells	https://github.com/geneontology/go-ontology/issues/19884			Wikipedia:Immune_complex									biological_process											owl:Class	
GO:0002434	biolink:NamedThing	immune complex clearance	A process directed at removing immune complexes from the body. Immune complexes are clusters of antibodies bound to antigen, to which complement may also be fixed, and which may precipitate or remain in solution.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0050434	biolink:NamedThing	positive regulation of viral transcription	Any process that activates or increases the frequency, rate or extent of viral transcription.	tmpzr1t_l9r_go_relaxed.owl	up regulation of viral transcription|activation of viral transcription|stimulation of viral transcription|up-regulation of viral transcription|upregulation of viral transcription													biological_process											owl:Class	
GO:1901308	biolink:NamedThing	regulation of sterol regulatory element binding protein cleavage	Any process that modulates the frequency, rate or extent of sterol regulatory element binding protein cleavage.	tmpzr1t_l9r_go_relaxed.owl	regulation of SREBP cleavage							bf	2012-08-21T16:43:12Z					biological_process											owl:Class	
GO:1903447	biolink:NamedThing	geraniol catabolic process	The chemical reactions and pathways resulting in the breakdown of geraniol.	tmpzr1t_l9r_go_relaxed.owl	geraniol degradation|geraniol breakdown|geraniol catabolism							di	2014-09-19T08:18:44Z					biological_process											owl:Class	
GO:1903708	biolink:NamedThing	positive regulation of hemopoiesis	Any process that activates or increases the frequency, rate or extent of hemopoiesis.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of hemopoiesis|up regulation of blood cell formation|positive regulation of blood cell formation|up-regulation of haemopoiesis|positive regulation of haemopoiesis|up regulation of haemopoiesis|upregulation of blood cell biosynthesis|up regulation of blood cell biosynthesis|activation of hemopoiesis|up-regulation of blood cell formation|up regulation of hemopoiesis|activation of hematopoiesis|activation of blood cell biosynthesis|activation of haemopoiesis|up-regulation of blood cell biosynthesis|activation of blood cell formation|upregulation of hemopoiesis|positive regulation of blood cell biosynthesis|up-regulation of hematopoiesis|upregulation of haemopoiesis|positive regulation of hematopoiesis|up regulation of hematopoiesis|upregulation of hematopoiesis|upregulation of blood cell formation					An example of this is Atg7 in mouse (UniProt symbol, Q9D906) in PMID:20080761, inferred from mutant phenotype.		pad	2014-12-04T15:34:30Z					biological_process											owl:Class	
GO:0003184	biolink:NamedThing	pulmonary valve morphogenesis	The process in which the structure of the pulmonary valve is generated and organized.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-10-08T12:03:35Z					biological_process											owl:Class	
GO:0003179	biolink:NamedThing	heart valve morphogenesis	The process in which the structure of a heart valve is generated and organized.	tmpzr1t_l9r_go_relaxed.owl	heart valve remodelling|heart valve remodeling							dph	2009-10-08T11:23:48Z					biological_process											owl:Class	
GO:0043702	biolink:NamedThing	carotenoid vesicle	A tissue-specific cytoplasmic vesicle surrounded by a membrane half-leaflet within which carotenoid pigments are stored. Carotenoid vesicles are synthesized in xanthophores and erythrophore cells and are yellow, orange or red in appearance.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0007382	biolink:NamedThing	specification of segmental identity, maxillary segment	The specification of the characteristic structures of the maxillary segment following establishment of segment boundaries. Identity is considered to be the aggregate of characteristics by which a structure is recognized.	tmpzr1t_l9r_go_relaxed.owl						See also the fly_anatomy.ontology term 'maxillary segment ; FBbt:00000013'.								biological_process											owl:Class	
GO:1900052	biolink:NamedThing	regulation of retinoic acid biosynthetic process	Any process that modulates the frequency, rate or extent of retinoic acid biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of retinoic acid anabolic process							yaf	2012-01-20T09:55:45Z					biological_process											owl:Class	
GO:0036317	biolink:NamedThing	tyrosyl-RNA phosphodiesterase activity	Catalysis of the hydrolysis of a 5' tyrosyl-RNA phosphodiester bond between a protein and RNA. In picornaviruses, this covalent bond connects VPg, a viral-encoded protein essential for RNA replication, to the 5' end of all nascent picornavirus genomes; it is cleaved from viral RNA prior to its engaging in protein synthesis.	tmpzr1t_l9r_go_relaxed.owl	Y-pUpN PDE activity|uridylylpolynucleotide-(5' P->O)- tyrosine phosphodiesterase activity|unlinkase activity|VPg unlinkase activity							bf	2012-08-30T11:08:04Z					molecular_function											owl:Class	
GO:2000529	biolink:NamedThing	positive regulation of myeloid dendritic cell chemotaxis	Any process that activates or increases the frequency, rate or extent of myeloid dendritic cell chemotaxis.	tmpzr1t_l9r_go_relaxed.owl								ebc	2011-03-23T12:18:45Z					biological_process											owl:Class	
GO:0060983	biolink:NamedThing	epicardium-derived cardiac vascular smooth muscle cell differentiation	The process in which a relatively unspecialized cell derived from the epicardium acquires specialized features of a cardiac vascular smooth muscle cell. A cardiac vascular smooth muscle cell covers the heart vasculature and lacks transverse striations in its constituent fibers.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-10-06T03:05:33Z					biological_process											owl:Class	
GO:0060947	biolink:NamedThing	cardiac vascular smooth muscle cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a cardiac vascular smooth muscle cell. A cardiac vascular smooth muscle cell covers the heart vasculature and lacks transverse striations in its constituent fibers.	tmpzr1t_l9r_go_relaxed.owl	heart vascular smooth muscle cell differentiation							dph	2009-09-29T02:56:08Z					biological_process											owl:Class	
GO:1904193	biolink:NamedThing	negative regulation of cholangiocyte apoptotic process	Any process that stops, prevents or reduces the frequency, rate or extent of cholangiocyte apoptotic process.	tmpzr1t_l9r_go_relaxed.owl	inhibition of cholangiocyte apoptotic process|downregulation of cholangiocyte apoptosis|negative regulation of cholangiocyte apoptosis|inhibition of epithelial cell of bile duct apoptotic process|down-regulation of cholangiocyte apoptotic process|inhibition of epithelial cell of bile duct apoptosis|down regulation of epithelial cell of bile duct apoptotic process|negative regulation of epithelial cell of bile duct apoptosis|down-regulation of epithelial cell of bile duct apoptotic process|down-regulation of epithelial cell of bile duct apoptosis|inhibition of cholangiocyte apoptosis|downregulation of cholangiocyte apoptotic process|down regulation of cholangiocyte apoptosis|down-regulation of cholangiocyte apoptosis|down regulation of epithelial cell of bile duct apoptosis|negative regulation of epithelial cell of bile duct apoptotic process|downregulation of epithelial cell of bile duct apoptotic process|downregulation of epithelial cell of bile duct apoptosis|down regulation of cholangiocyte apoptotic process							sl	2015-05-06T15:25:55Z					biological_process											owl:Class	
GO:0050357	biolink:NamedThing	tropinesterase activity	Catalysis of the reaction: atropine + H(2)O = H(+) + tropate + tropine.	tmpzr1t_l9r_go_relaxed.owl	atropine acylhydrolase activity|atropinesterase activity|atropinase activity|tropine esterase activity|atropine esterase activity				KEGG_REACTION:R03563|MetaCyc:TROPINESTERASE-RXN|EC:3.1.1.10|RHEA:23304									molecular_function											owl:Class	
GO:1902833	biolink:NamedThing	positive regulation of cell proliferation in dorsal spinal cord	Any process that activates or increases the frequency, rate or extent of cell proliferation in dorsal spinal cord.	tmpzr1t_l9r_go_relaxed.owl	activation of cell proliferation in dorsal spinal cord|up regulation of cell proliferation in dorsal spinal cord|up-regulation of cell proliferation in dorsal spinal cord|upregulation of cell proliferation in dorsal spinal cord							mr	2014-03-31T17:43:33Z					biological_process											owl:Class	
GO:0032762	biolink:NamedThing	mast cell cytokine production	Any process that contributes to cytokine production by a mast cell.	tmpzr1t_l9r_go_relaxed.owl						Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.								biological_process											owl:Class	
GO:0061082	biolink:NamedThing	myeloid leukocyte cytokine production	Any process that contributes to cytokine production by a myeloid cell.	tmpzr1t_l9r_go_relaxed.owl						Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.		dph	2010-04-13T11:29:42Z					biological_process											owl:Class	
GO:0046805	biolink:NamedThing	protein-heme linkage via 1'-L-histidine	The covalent linkage of heme and a protein via 1'-L-histidine (otherwise known as tau-heme-histidine, tele-heme-histidine).	tmpzr1t_l9r_go_relaxed.owl	protein-haem linkage via 1'-L-histidine				RESID:AA0329									biological_process											owl:Class	
GO:0102976	biolink:NamedThing	versiconal reductase activity	Catalysis of the reaction: versiconol + NADP <=> versiconal hemiacetal + NADPH + H+.	tmpzr1t_l9r_go_relaxed.owl					RHEA:35699|MetaCyc:RXN-9491|EC:1.1.1.353									molecular_function											owl:Class	
GO:1900877	biolink:NamedThing	nonadec-1-ene biosynthetic process	The chemical reactions and pathways resulting in the formation of nonadec-1-ene.	tmpzr1t_l9r_go_relaxed.owl	nonadec-1-ene formation|nonadec-1-ene anabolism|nonadec-1-ene biosynthesis|nonadec-1-ene synthesis							tt	2012-06-13T01:52:37Z					biological_process											owl:Class	
GO:1900876	biolink:NamedThing	nonadec-1-ene metabolic process	The chemical reactions and pathways involving nonadec-1-ene.	tmpzr1t_l9r_go_relaxed.owl	nonadec-1-ene metabolism							tt	2012-06-13T01:52:09Z					biological_process											owl:Class	
GO:0001711	biolink:NamedThing	endodermal cell fate commitment	The cell differentiation process that results in commitment of a cell to become part of the endoderm.	tmpzr1t_l9r_go_relaxed.owl	endoderm cell fate commitment													biological_process											owl:Class	
GO:0060795	biolink:NamedThing	cell fate commitment involved in formation of primary germ layer	The commitment of cells to specific cell fates of the endoderm, ectoderm, or mesoderm as a part of gastrulation.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-08-04T03:11:22Z					biological_process											owl:Class	
GO:0006557	biolink:NamedThing	S-adenosylmethioninamine biosynthetic process	The chemical reactions and pathways resulting in the formation of S-adenosylmethioninamine, (5-deoxy-5-adenosyl)(3-aminopropyl) methylsulfonium salt.	tmpzr1t_l9r_go_relaxed.owl	S-adenosylmethioninamine synthesis|S-adenosylmethioninamine formation|S-adenosylmethioninamine biosynthesis|S-adenosylmethioninamine anabolism											GO:0006745		biological_process											owl:Class	
GO:0031031	biolink:NamedThing	positive regulation of septation initiation signaling	Any process that activates or increases the frequency, rate or extent of septation initiation signaling.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of septation initiation signaling|positive regulation of septation initiation signalling|upregulation of septation initiation signaling|positive regulation of septation initiation signaling cascade|stimulation of septation initiation signaling|positive regulation of septation initiation network|up regulation of septation initiation signaling|activation of septation initiation signaling													biological_process											owl:Class	
GO:0051552	biolink:NamedThing	flavone metabolic process	The chemical reactions and pathways involving flavones, a class of pigmented plant compounds based on 2-phenyl-4H-1-benzopyran-4-one (2-phenylchromone).	tmpzr1t_l9r_go_relaxed.owl	2-phenyl-4H-1-benzopyran-4-one metabolism|2-phenylchromone metabolism|2-phenylchromone metabolic process|flavone metabolism|2-phenyl-4H-1-benzopyran-4-one metabolic process													biological_process											owl:Class	
GO:0030699	biolink:NamedThing	glycine reductase activity	Catalysis of the reaction: acetyl phosphate + H(2)O + NH(4)(+) + thioredoxin disulfide = glycine + H(+) + phosphate + thioredoxin.	tmpzr1t_l9r_go_relaxed.owl	acetyl-phosphate ammonia:thioredoxin disulfide oxidoreductase (glycine-forming)				EC:1.21.4.2|RHEA:12232|MetaCyc:RXN-7566|KEGG_REACTION:R07226									molecular_function											owl:Class	
GO:0050485	biolink:NamedThing	oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond, with a disulfide as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which X-H and Y-H form X-Y and the acceptor is disulfide.	tmpzr1t_l9r_go_relaxed.owl	oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond, with a disulphide as acceptor				EC:1.21.4.-									molecular_function											owl:Class	
GO:0140546	biolink:NamedThing	defense response to symbiont	Reactions triggered in response to the presence of a symbiont that act to protect the cell or organism from damage caused by that symbiont.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/20261						pg	2020-11-11T17:19:06Z					biological_process											owl:Class	
GO:0002081	biolink:NamedThing	outer acrosomal membrane	The acrosomal membrane region that underlies the plasma membrane of the sperm. This membrane fuses with the sperm plasma membrane as part of the acrosome reaction.	tmpzr1t_l9r_go_relaxed.owl						Note that this term is not a descendant of 'organelle outer membrane ; GO:0031968' because the outer acrosomal membrane is a portion of the acrosomal membrane; the latter is a single lipid bilayer.								cellular_component											owl:Class	
GO:0030659	biolink:NamedThing	cytoplasmic vesicle membrane	The lipid bilayer surrounding a cytoplasmic vesicle.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0140547	biolink:NamedThing	acquisition of seed longevity	The acquisition of seed longevity is the ordered series of events during seed development, that prevent embryo deterioration and ROS damage and thus contribute to seed viability over time or in response to adverse environmental conditions. These events include protective (e.g. production of glassy cytoplasm ) and repair (e.g. oxidative stress responses) processes.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/19829						pg	2020-11-11T21:28:55Z					biological_process											owl:Class	
GO:0001700	biolink:NamedThing	embryonic development via the syncytial blastoderm	The process whose specific outcome is the progression of the embryo over time, from zygote formation through syncytial blastoderm to the hatching of the first instar larva. An example of this process is found in Drosophila melanogaster.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0009792	biolink:NamedThing	embryo development ending in birth or egg hatching	The process whose specific outcome is the progression of an embryo over time, from zygote formation until the end of the embryonic life stage. The end of the embryonic life stage is organism-specific and may be somewhat arbitrary; for mammals it is usually considered to be birth, for insects the hatching of the first instar larva from the eggshell.	tmpzr1t_l9r_go_relaxed.owl	embryogenesis													biological_process											owl:Class	
GO:0060654	biolink:NamedThing	mammary gland cord elongation	The process in which the mammary gland sprout grows along its axis.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-05-29T09:26:15Z					biological_process											owl:Class	
GO:1904747	biolink:NamedThing	positive regulation of apoptotic process involved in development	Any process that activates or increases the frequency, rate or extent of apoptotic process involved in development.	tmpzr1t_l9r_go_relaxed.owl	activation of induction of apoptosis by p53 involved in development of an anatomical structure|up regulation of programmed cell death by apoptosis involved in anatomical structure development|up regulation of apoptosis signaling involved in development of an anatomical structure|upregulation of apoptotic programmed cell death involved in anatomical structure development|up regulation of apoptotic cell death involved in development of an anatomical structure|activation of induction of apoptosis involved in anatomical structure development|up regulation of apoptosis activator activity involved in development of an anatomical structure|positive regulation of programmed cell death by apoptosis involved in anatomical structure development|positive regulation of programmed cell death by apoptosis involved in development of an anatomical structure|up-regulation of programmed cell death by apoptosis involved in anatomical structure development|activation of apoptotic process involved in development of an anatomical structure|upregulation of induction of apoptosis by p53 involved in anatomical structure development|up-regulation of apoptotic process involved in anatomical structure development|activation of apoptosis activator activity involved in anatomical structure development|up-regulation of apoptotic process involved in development of an anatomical structure|up-regulation of apoptotic cell death involved in development of an anatomical structure|up regulation of commitment to apoptosis involved in anatomical structure development|positive regulation of signaling (initiator) caspase activity involved in development of an anatomical structure|upregulation of induction of apoptosis involved in anatomical structure development|up regulation of induction of apoptosis by p53 involved in anatomical structure development|up-regulation of apoptosis involved in development of an anatomical structure|up regulation of apoptotic process involved in development of an anatomical structure|upregulation of apoptosis activator activity involved in development of an anatomical structure|up-regulation of commitment to apoptosis involved in anatomical structure development|upregulation of signaling (initiator) caspase activity involved in anatomical structure development|up-regulation of programmed cell death by apoptosis involved in development of an anatomical structure|up regulation of apoptotic programmed cell death involved in development of an anatomical structure|upregulation of apoptosis signaling involved in development of an anatomical structure|upregulation of apoptotic cell death involved in development of an anatomical structure|up-regulation of apoptotic cell death involved in anatomical structure development|up regulation of apoptosis involved in development of an anatomical structure|activation of apoptotic cell death involved in development of an anatomical structure|up regulation of programmed cell death by apoptosis involved in development of an anatomical structure|up-regulation of signaling (initiator) caspase activity involved in development of an anatomical structure|upregulation of apoptosis involved in development of an anatomical structure|upregulation of apoptotic program involved in development of an anatomical structure|up-regulation of apoptotic program involved in development of an anatomical structure|activation of activation of apoptosis involved in development of an anatomical structure|upregulation of programmed cell death by apoptosis involved in anatomical structure development|up-regulation of type I programmed cell death involved in anatomical structure development|up-regulation of activation of apoptosis involved in anatomical structure development|activation of type I programmed cell death involved in development of an anatomical structure|up regulation of apoptosis activator activity involved in anatomical structure development|positive regulation of apoptotic program involved in anatomical structure development|activation of apoptotic process involved in anatomical structure development|up regulation of signaling (initiator) caspase activity involved in development of an anatomical structure|activation of commitment to apoptosis involved in anatomical structure development|up-regulation of apoptosis activator activity involved in development of an anatomical structure|up-regulation of induction of apoptosis by p53 involved in development of an anatomical structure|positive regulation of apoptotic programmed cell death involved in development of an anatomical structure|positive regulation of apoptotic process involved in development of an anatomical structure|up-regulation of induction of apoptosis involved in anatomical structure development|upregulation of apoptotic program involved in anatomical structure development|activation of apoptotic process involved in development|upregulation of apoptotic process involved in development|upregulation of induction of apoptosis by p53 involved in development of an anatomical structure|up-regulation of apoptosis signaling involved in development of an anatomical structure|activation of apoptosis signaling involved in development of an anatomical structure|activation of apoptotic program involved in anatomical structure development|up-regulation of type I programmed cell death involved in development of an anatomical structure|up regulation of apoptotic program involved in development of an anatomical structure|positive regulation of apoptotic cell death involved in development of an anatomical structure|upregulation of apoptotic process involved in development of an anatomical structure|positive regulation of signaling (initiator) caspase activity involved in anatomical structure development|up regulation of apoptotic programmed cell death involved in anatomical structure development|positive regulation of apoptotic cell death involved in anatomical structure development|positive regulation of apoptosis activator activity involved in development of an anatomical structure|positive regulation of apoptotic process involved in anatomical structure development|positive regulation of induction of apoptosis by p53 involved in development of an anatomical structure|activation of apoptotic program involved in development of an anatomical structure|up regulation of apoptotic process involved in development|positive regulation of induction of apoptosis involved in development of an anatomical structure|up-regulation of signaling (initiator) caspase activity involved in anatomical structure development|positive regulation of induction of apoptosis by p53 involved in anatomical structure development|activation of apoptotic programmed cell death involved in development of an anatomical structure|up regulation of apoptosis involved in anatomical structure development|up regulation of induction of apoptosis involved in anatomical structure development|positive regulation of apoptosis signaling involved in anatomical structure development|activation of apoptosis signaling involved in anatomical structure development|positive regulation of type I programmed cell death involved in development of an anatomical structure|activation of apoptosis involved in development of an anatomical structure|up regulation of activation of apoptosis involved in anatomical structure development|upregulation of programmed cell death by apoptosis involved in development of an anatomical structure|up regulation of apoptosis signaling involved in anatomical structure development|up-regulation of apoptosis signaling involved in anatomical structure development|positive regulation of apoptosis involved in anatomical structure development|activation of programmed cell death by apoptosis involved in anatomical structure development|upregulation of signaling (initiator) caspase activity involved in development of an anatomical structure|positive regulation of activation of apoptosis involved in anatomical structure development|up-regulation of activation of apoptosis involved in development of an anatomical structure|up regulation of induction of apoptosis by p53 involved in development of an anatomical structure|up regulation of apoptotic cell death involved in anatomical structure development|positive regulation of apoptotic program involved in development of an anatomical structure|positive regulation of type I programmed cell death involved in anatomical structure development|activation of apoptotic cell death involved in anatomical structure development|upregulation of apoptosis involved in anatomical structure development|upregulation of apoptosis signaling involved in anatomical structure development|up regulation of activation of apoptosis involved in development of an anatomical structure|up-regulation of apoptotic programmed cell death involved in development of an anatomical structure|up-regulation of apoptosis activator activity involved in anatomical structure development|activation of signaling (initiator) caspase activity involved in anatomical structure development|up regulation of apoptotic program involved in anatomical structure development|activation of apoptosis activator activity involved in development of an anatomical structure|upregulation of apoptotic process involved in anatomical structure development|positive regulation of commitment to apoptosis involved in development of an anatomical structure|up regulation of type I programmed cell death involved in development of an anatomical structure|positive regulation of apoptosis signaling involved in development of an anatomical structure|up-regulation of induction of apoptosis by p53 involved in anatomical structure development|activation of commitment to apoptosis involved in development of an anatomical structure|activation of activation of apoptosis involved in anatomical structure development|activation of induction of apoptosis by p53 involved in anatomical structure development|upregulation of activation of apoptosis involved in development of an anatomical structure|upregulation of commitment to apoptosis involved in anatomical structure development|activation of apoptosis involved in anatomical structure development|up-regulation of induction of apoptosis involved in development of an anatomical structure|up-regulation of commitment to apoptosis involved in development of an anatomical structure|positive regulation of commitment to apoptosis involved in anatomical structure development|upregulation of commitment to apoptosis involved in development of an anatomical structure|up regulation of induction of apoptosis involved in development of an anatomical structure|up-regulation of apoptosis involved in anatomical structure development|positive regulation of apoptotic programmed cell death involved in anatomical structure development|activation of induction of apoptosis involved in development of an anatomical structure|upregulation of apoptotic programmed cell death involved in development of an anatomical structure|up-regulation of apoptotic program involved in anatomical structure development|positive regulation of apoptosis activator activity involved in anatomical structure development|up-regulation of apoptotic process involved in development|activation of type I programmed cell death involved in anatomical structure development|up-regulation of apoptotic programmed cell death involved in anatomical structure development|upregulation of induction of apoptosis involved in development of an anatomical structure|up regulation of signaling (initiator) caspase activity involved in anatomical structure development|upregulation of apoptotic cell death involved in anatomical structure development|activation of apoptotic programmed cell death involved in anatomical structure development|upregulation of activation of apoptosis involved in anatomical structure development|activation of programmed cell death by apoptosis involved in development of an anatomical structure|positive regulation of induction of apoptosis involved in anatomical structure development|up regulation of type I programmed cell death involved in anatomical structure development|positive regulation of activation of apoptosis involved in development of an anatomical structure|upregulation of apoptosis activator activity involved in anatomical structure development|up regulation of commitment to apoptosis involved in development of an anatomical structure|upregulation of type I programmed cell death involved in anatomical structure development|activation of signaling (initiator) caspase activity involved in development of an anatomical structure|up regulation of apoptotic process involved in anatomical structure development|positive regulation of apoptosis involved in development of an anatomical structure|upregulation of type I programmed cell death involved in development of an anatomical structure					U4PR86 in PMID:22801495 inferred from mutant phenotype		es	2015-10-19T14:12:34Z					biological_process											owl:Class	
GO:1904748	biolink:NamedThing	regulation of apoptotic process involved in development	Any process that modulates the frequency, rate or extent of apoptotic process involved in development.	tmpzr1t_l9r_go_relaxed.owl	regulation of commitment to apoptosis involved in development of an anatomical structure|regulation of apoptosis activator activity involved in anatomical structure development|regulation of apoptotic programmed cell death involved in development of an anatomical structure|regulation of apoptosis signaling involved in development of an anatomical structure|regulation of activation of apoptosis involved in development of an anatomical structure|regulation of apoptosis involved in anatomical structure development|regulation of apoptosis activator activity involved in development of an anatomical structure|regulation of induction of apoptosis by p53 involved in anatomical structure development|regulation of apoptosis involved in development of an anatomical structure|regulation of type I programmed cell death involved in anatomical structure development|regulation of programmed cell death by apoptosis involved in development of an anatomical structure|regulation of activation of apoptosis involved in anatomical structure development|regulation of type I programmed cell death involved in development of an anatomical structure|regulation of induction of apoptosis by p53 involved in development of an anatomical structure|regulation of signaling (initiator) caspase activity involved in anatomical structure development|regulation of apoptotic cell death involved in development of an anatomical structure|regulation of programmed cell death by apoptosis involved in anatomical structure development|regulation of apoptotic process involved in anatomical structure development|regulation of apoptotic programmed cell death involved in anatomical structure development|regulation of commitment to apoptosis involved in anatomical structure development|regulation of apoptotic program involved in anatomical structure development|regulation of apoptosis signaling involved in anatomical structure development|regulation of induction of apoptosis involved in anatomical structure development|regulation of apoptotic cell death involved in anatomical structure development|regulation of signaling (initiator) caspase activity involved in development of an anatomical structure|regulation of apoptotic process involved in development of an anatomical structure|regulation of induction of apoptosis involved in development of an anatomical structure|regulation of apoptotic program involved in development of an anatomical structure					Q10943 in PMID:22801495, inferred from mutant phenotype		es	2015-10-19T15:02:28Z					biological_process											owl:Class	
GO:0051973	biolink:NamedThing	positive regulation of telomerase activity	Any process that activates or increases the frequency, rate or extent of telomerase activity, the catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).	tmpzr1t_l9r_go_relaxed.owl	stimulation of telomerase activity|up regulation of telomerase activity|upregulation of telomerase activity|activation of telomerase activity|up-regulation of telomerase activity|telomerase activator													biological_process											owl:Class	
GO:1904923	biolink:NamedThing	regulation of autophagy of mitochondrion in response to mitochondrial depolarization	Any process that modulates the frequency, rate or extent of autophagy of mitochondrion in response to mitochondrial depolarization.	tmpzr1t_l9r_go_relaxed.owl								pad	2016-01-26T11:23:50Z					biological_process											owl:Class	
GO:0098780	biolink:NamedThing	response to mitochondrial depolarisation	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) in response to the depolarization of one or more mitochondria.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0045147	biolink:NamedThing	regulation of initiation of acetate catabolic process by acetate	Any process that modulates the activation, by acetate, of the chemical reactions and pathways resulting in the breakdown of acetate.	tmpzr1t_l9r_go_relaxed.owl	regulation of initiation of acetate breakdown by acetate|regulation of initiation of acetate degradation by acetate													biological_process											owl:Class	
GO:1901457	biolink:NamedThing	regulation of response to acetate	Any process that modulates the frequency, rate or extent of response to acetate.	tmpzr1t_l9r_go_relaxed.owl								tt	2012-10-02T14:25:06Z					biological_process											owl:Class	
GO:0009568	biolink:NamedThing	amyloplast starch grain	Plant storage body for amylose and amylopectin, 1-100um in diameter, and located in amyloplasts. Also contains small amounts of enzymes, amino acids, lipids and nucleic acids. The shape of the grain varies widely amongst species, but is often spherical or disk-shaped.	tmpzr1t_l9r_go_relaxed.owl	amyloplast starch granule													cellular_component											owl:Class	
GO:0043036	biolink:NamedThing	starch grain	Plant storage body for amylose and amylopectin, 1-100um in diameter. Also contains small amounts of enzymes, amino acids, lipids and nucleic acids. The shape of the grain varies widely amongst species, but is often spherical or disk-shaped.	tmpzr1t_l9r_go_relaxed.owl	starch granule													cellular_component											owl:Class	
GO:0052588	biolink:NamedThing	diacetyl reductase ((S)-acetoin forming) activity	Catalysis of the reaction: (S)-acetoin + NAD(+) = diacetyl + H(+) + NADH.	tmpzr1t_l9r_go_relaxed.owl	(S)-acetoin dehydrogenase activity				MetaCyc:RXN-11032|KEGG_REACTION:R09078|EC:1.1.1.304|RHEA:27286									molecular_function											owl:Class	
GO:0034894	biolink:NamedThing	4-hydroxypyridine-3-hydroxylase activity	Catalysis of the reaction: 4-hydroxypyridine + O2 + H+ + NADPH = pyridine-3,4-diol + H2O + NADP+.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r1397|EC:1.14.13.-									molecular_function											owl:Class	
GO:1905957	biolink:NamedThing	regulation of cellular response to alcohol	Any process that modulates the frequency, rate or extent of cellular response to alcohol.	tmpzr1t_l9r_go_relaxed.owl								hbye	2017-02-22T12:03:00Z					biological_process											owl:Class	
GO:0031666	biolink:NamedThing	positive regulation of lipopolysaccharide-mediated signaling pathway	Any process that activates or increases the frequency, rate or extent of signaling in response to detection of lipopolysaccharide.	tmpzr1t_l9r_go_relaxed.owl	up regulation of lipopolysaccharide-mediated signaling pathway|positive regulation of LPS-mediated signaling pathway|stimulation of lipopolysaccharide-mediated signaling pathway|up-regulation of lipopolysaccharide-mediated signaling pathway|upregulation of lipopolysaccharide-mediated signaling pathway|activation of lipopolysaccharide-mediated signaling pathway|positive regulation of lipopolysaccharide-mediated signalling pathway													biological_process											owl:Class	
GO:0031664	biolink:NamedThing	regulation of lipopolysaccharide-mediated signaling pathway	Any process that modulates the frequency, rate or extent of signaling in response to detection of lipopolysaccharide.	tmpzr1t_l9r_go_relaxed.owl	regulation of LPS-mediated signaling pathway|regulation of lipopolysaccharide-mediated signalling pathway													biological_process											owl:Class	
GO:0043204	biolink:NamedThing	perikaryon	The portion of the cell soma (neuronal cell body) that excludes the nucleus.	tmpzr1t_l9r_go_relaxed.owl	cell soma cytoplasm													cellular_component											owl:Class	
GO:0060880	biolink:NamedThing	cell morphogenesis involved in semicircular canal fusion	The change in form (cell shape and size) that occurs when a semicircular canal epithelial cell acquires the structural features that allow it to contribute to the process of semicircular canal fusion.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-08-13T10:13:25Z					biological_process											owl:Class	
GO:1904685	biolink:NamedThing	positive regulation of metalloendopeptidase activity	Any process that activates or increases the frequency, rate or extent of metalloendopeptidase activity.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of metalloendoproteinase activity|positive regulation of metalloendoprotease activity|upregulation of metalloendoprotease activity|up-regulation of metalloendopeptidase activity|up regulation of metalloendoprotease activity|up-regulation of metalloendoprotease activity|activation of metalloendoprotease activity|upregulation of metalloendopeptidase activity|up regulation of metalloendoproteinase activity|activation of metalloendopeptidase activity|activation of metalloendoproteinase activity|positive regulation of metalloendoproteinase activity|upregulation of metalloendoproteinase activity|up regulation of metalloendopeptidase activity							rph	2015-09-24T11:18:28Z					biological_process											owl:Class	
GO:0098907	biolink:NamedThing	regulation of SA node cell action potential	Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in an SA node cardiac myocyte. This typically occurs via modulation of the activity or expression of voltage-gated ion channels.	tmpzr1t_l9r_go_relaxed.owl	regulation of SAN cardiac muscle cell action potential|regulation of sinoatrial node cardiac muscle cell action potential|regulation of sinus node cardiac muscle cell action potential|regulation of SA node cardiac muscle cell action potential							tb	2011-11-10T08:50:15Z					biological_process											owl:Class	
GO:0046832	biolink:NamedThing	negative regulation of RNA export from nucleus	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of RNA from the nucleus into the cytoplasm.	tmpzr1t_l9r_go_relaxed.owl	downregulation of RNA export from nucleus|negative regulation of RNA-nucleus export|down regulation of RNA export from nucleus|negative regulation of RNA export from cell nucleus|inhibition of RNA export from nucleus|negative regulation of RNA transport from nucleus to cytoplasm|negative regulation of RNA export out of nucleus|down-regulation of RNA export from nucleus													biological_process											owl:Class	
GO:1901366	biolink:NamedThing	funalenone biosynthetic process	The chemical reactions and pathways resulting in the formation of funalenone.	tmpzr1t_l9r_go_relaxed.owl	funalenone biosynthesis|funalenone formation|funalenone synthesis|funalenone anabolism							di	2012-09-17T18:25:47Z					biological_process											owl:Class	
GO:0004318	biolink:NamedThing	enoyl-[acyl-carrier-protein] reductase (NADH) activity	Catalysis of the reaction: acyl-[acyl-carrier protein] + NAD+ = trans-2,3-dehydroacyl-[acyl-carrier protein] + NADH + H+.	tmpzr1t_l9r_go_relaxed.owl	enoyl-[acyl-carrier protein] reductase (NADH) activity|enoyl-acyl-carrier-protein reductase (NADH)|enoyl-ACP reductase (NADH) activity|NADH-specific enoyl-ACP reductase activity|NADH-enoyl acyl carrier protein reductase activity|acyl-acyl-carrier-protein:NAD+ oxidoreductase				EC:1.3.1.9|MetaCyc:ENOYL-ACP-REDUCT-NADH-RXN									molecular_function											owl:Class	
GO:0050350	biolink:NamedThing	trihydroxystilbene synthase activity	Catalysis of the reaction: 3 malonyl-CoA + 4-coumaroyl-CoA = 4 CoA + 3,4',5-trihydroxy-stilbene + 4 CO2.	tmpzr1t_l9r_go_relaxed.owl	malonyl-CoA:4-coumaroyl-CoA malonyltransferase (cyclizing)|stilbene synthase activity|resveratrol synthase activity				EC:2.3.1.95|RHEA:11936|MetaCyc:TRIHYDROXYSTILBENE-SYNTHASE-RXN									molecular_function											owl:Class	
GO:0035315	biolink:NamedThing	hair cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a hair cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0072531	biolink:NamedThing	pyrimidine-containing compound transmembrane transport	The process in which a pyrimidine-containing compound is transported across a membrane. A pyrimidine-containing compound is any compound that contains pyrimidine or a formal derivative thereof.	tmpzr1t_l9r_go_relaxed.owl	pyrimidine-containing compound membrane transport					Note that this term is not intended for use in annotating lateral movement within membranes.		mah	2011-01-05T01:47:22Z					biological_process											owl:Class	
GO:0045648	biolink:NamedThing	positive regulation of erythrocyte differentiation	Any process that activates or increases the frequency, rate or extent of erythrocyte differentiation.	tmpzr1t_l9r_go_relaxed.owl	activation of erythrocyte differentiation|up-regulation of erythrocyte differentiation|up regulation of erythrocyte differentiation|stimulation of erythrocyte differentiation|positive regulation of RBC differentiation|positive regulation of red blood cell differentiation|upregulation of erythrocyte differentiation													biological_process											owl:Class	
GO:0045646	biolink:NamedThing	regulation of erythrocyte differentiation	Any process that modulates the frequency, rate or extent of erythrocyte differentiation.	tmpzr1t_l9r_go_relaxed.owl	regulation of red blood cell differentiation|regulation of RBC differentiation													biological_process											owl:Class	
GO:0047195	biolink:NamedThing	diacylglycerol-sterol O-acyltransferase activity	Catalysis of the reaction: sterol + 1,2-diacylglycerol = sterol ester + acylglycerol.	tmpzr1t_l9r_go_relaxed.owl	1,2-diacyl-sn-glycerol:sterol acyl transferase activity|1,2-diacyl-sn-glycerol:sterol O-acyltransferase activity				EC:2.3.1.73|RHEA:13301|MetaCyc:2.3.1.73-RXN									molecular_function											owl:Class	
GO:0055041	biolink:NamedThing	cyclopentanol dehydrogenase activity	Catalysis of the reaction: cyclopentanol + NAD(+) = cyclopentanone + H(+) + NADH.	tmpzr1t_l9r_go_relaxed.owl	cyclopentanol:NADP+ oxidoreductase activity|cyclopentanol:NAD+ oxidoreductase activity				KEGG_REACTION:R02553|MetaCyc:CYCLOPENTANOL-DEHYDROGENASE-RXN|EC:1.1.1.163|RHEA:11728									molecular_function											owl:Class	
GO:0009830	biolink:NamedThing	cell wall modification involved in abscission	A cellular process that results in the breakdown of the cell wall that contributes to the process of abscission.	tmpzr1t_l9r_go_relaxed.owl	cell wall modification during abscission													biological_process											owl:Class	
GO:0042545	biolink:NamedThing	cell wall modification	The series of events leading to chemical and structural alterations of an existing cell wall that can result in loosening, increased extensibility or disassembly.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0014803	biolink:NamedThing	longitudinal sarcoplasmic reticulum lumen	The region between the inner and outer lipid bilayers of the longitudinal sarcoplasmic reticulum envelope. The longitudinal sarcoplasmic reticulum lumen is continuous with the lumen contained within the terminal cisternae.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:1905851	biolink:NamedThing	negative regulation of backward locomotion	Any process that stops, prevents or reduces the frequency, rate or extent of backward locomotion.	tmpzr1t_l9r_go_relaxed.owl	inhibition of backward locomotion|down-regulation of backward locomotion|downregulation of backward locomotion|down regulation of backward locomotion							rz	2017-01-23T11:04:16Z					biological_process											owl:Class	
GO:0001678	biolink:NamedThing	cellular glucose homeostasis	A cellular homeostatic process involved in the maintenance of an internal steady state of glucose within a cell or between a cell and its external environment.	tmpzr1t_l9r_go_relaxed.owl	cell glucose homeostasis													biological_process											owl:Class	
GO:0004775	biolink:NamedThing	succinate-CoA ligase (ADP-forming) activity	Catalysis of the reaction: ATP + succinate + CoA = ADP + succinyl-CoA + phosphate.	tmpzr1t_l9r_go_relaxed.owl	succinyl coenzyme A synthetase (adenosine diphosphate-forming) activity|succinate thiokinase activity|succinate:CoA ligase (ADP-forming) activity|succinyl-CoA synthetase (ADP-forming) activity|succinic thiokinase|succinyl coenzyme A synthetase|A-STK (adenin nucleotide-linked succinate thiokinase)|A-SCS|succinyl-CoA synthetase activity				RHEA:17661|Reactome:R-HSA-70997|KEGG_REACTION:R00405|MetaCyc:SUCCCOASYN-RXN|EC:6.2.1.5									molecular_function											owl:Class	
GO:0004774	biolink:NamedThing	succinate-CoA ligase activity	Catalysis of the reaction: succinate + CoA + nucleotide triphosphate = nucleotide diphosphate + phosphate + succinyl-CoA.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0006168	biolink:NamedThing	adenine salvage	Any process that generates adenine, 6-aminopurine, from derivatives of it without de novo synthesis.	tmpzr1t_l9r_go_relaxed.owl	adenine salvage pathway|adenine, hypoxanthine and their nucleoside salvage													biological_process											owl:Class	
GO:0046084	biolink:NamedThing	adenine biosynthetic process	The chemical reactions and pathways resulting in the formation of adenine, 6-aminopurine, one of the five main bases found in nucleic acids and a component of numerous important derivatives of its corresponding ribonucleoside, adenosine.	tmpzr1t_l9r_go_relaxed.owl	adenine biosynthesis|adenine synthesis|adenine formation|adenine anabolism													biological_process											owl:Class	
GO:0043321	biolink:NamedThing	regulation of natural killer cell degranulation	Any process that modulates the frequency, rate, or extent of natural killer cell degranulation.	tmpzr1t_l9r_go_relaxed.owl	regulation of NK cell granule exocytosis|regulation of natural killer cell granule exocytosis|regulation of NK cell degranulation													biological_process											owl:Class	
GO:0061253	biolink:NamedThing	mesonephric glomerular parietal epithelial cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a mesonephric glomerular parietal epithelial cell. Mesonephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-08-30T01:26:47Z					biological_process											owl:Class	
GO:0072139	biolink:NamedThing	glomerular parietal epithelial cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a glomerular parietal epithelial cell. Glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-02-24T01:33:05Z					biological_process											owl:Class	
GO:1903469	biolink:NamedThing	removal of RNA primer involved in mitotic DNA replication	Any DNA replication, removal of RNA primer that is involved in mitotic cell cycle DNA replication.	tmpzr1t_l9r_go_relaxed.owl	DNA replication, removal of RNA primer involved in DNA replication involved in S-phase involved in mitotic cell cycle|DNA replication, removal of RNA primer involved in mitotic nuclear cell cycle DNA replication|Okazaki initiator RNA removal involved in mitotic cell cycle DNA replication|Okazaki initiator RNA removal involved in nuclear cell cycle DNA replication involved in mitotic cell cycle|DNA replication, removal of RNA primer involved in nuclear cell cycle DNA replication involved in mitotic cell cycle|Okazaki initiator RNA removal involved in DNA replication involved in S phase involved in mitotic cell cycle|Okazaki initiator RNA removal involved in DNA replication involved in S-phase involved in mitotic cell cycle|DNA replication, removal of RNA primer involved in DNA replication involved in S phase involved in mitotic cell cycle|Okazaki initiator RNA removal involved in mitotic nuclear cell cycle DNA replication|Okazaki initiator RNA removal involved in DNA replication during S phase involved in mitotic cell cycle|DNA replication, removal of RNA primer involved in DNA replication during S phase involved in mitotic cell cycle							vw	2014-09-23T13:42:24Z					biological_process											owl:Class	
GO:1904215	biolink:NamedThing	regulation of protein import into chloroplast stroma	Any process that modulates the frequency, rate or extent of protein import into chloroplast stroma.	tmpzr1t_l9r_go_relaxed.owl	regulation of protein transport into chloroplast stroma|regulation of chloroplast stroma protein import							tb	2015-05-15T00:47:48Z					biological_process											owl:Class	
GO:0031640	biolink:NamedThing	killing of cells of other organism	Any process in an organism that results in the killing of cells of another organism, including in some cases the death of the other organism. Killing here refers to the induction of death in one cell by another cell, not cell-autonomous death due to internal or other environmental conditions.	tmpzr1t_l9r_go_relaxed.owl	killing of cells of another organism|killing of cells of another, non-host, organism											GO:0001908		biological_process											owl:Class	
GO:0044419	biolink:NamedThing	biological process involved in interspecies interaction between organisms	Any process evolved to enable an interaction with an organism of a different species.	tmpzr1t_l9r_go_relaxed.owl	interspecies interaction between organisms|interaction with another species|interspecies interaction|interspecies interaction with other organisms	https://github.com/geneontology/go-ontology/issues/20191												biological_process											owl:Class	
GO:0071358	biolink:NamedThing	cellular response to type III interferon	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a type III interferon stimulus. Interferon lambda is the only member of the type III interferon found so far.	tmpzr1t_l9r_go_relaxed.owl	cellular response to interferon-lambda|cellular response to type III IFN							mah	2009-12-11T02:52:00Z					biological_process											owl:Class	
GO:0102758	biolink:NamedThing	very-long-chain enoyl-CoA reductase activity	Catalysis of the reaction: NADP(3-) + a very-long-chain 2,3,4-saturated fatty acyl CoA <=> NADPH(4-) + H+ + a very-long-chain trans-2,3-dehydroacyl-CoA.	tmpzr1t_l9r_go_relaxed.owl					EC:1.3.1.93|MetaCyc:RXN-7711|RHEA:14473									molecular_function											owl:Class	
GO:0045088	biolink:NamedThing	regulation of innate immune response	Any process that modulates the frequency, rate or extent of the innate immune response, the organism's first line of defense against infection.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0032660	biolink:NamedThing	regulation of interleukin-17 production	Any process that modulates the frequency, rate, or extent of production of any member of the interleukin-17 family of cytokines.	tmpzr1t_l9r_go_relaxed.owl	regulation of interleukin-17 secretion|regulation of CTLA-8 production|regulation of IL-17 production|regulation of interleukin-17 biosynthetic process|regulation of Cytotoxic T-lymphocyte-associated antigen 8 secretion											GO:1905076|GO:0045378		biological_process											owl:Class	
GO:2000879	biolink:NamedThing	negative regulation of dipeptide transport	Any process that stops, prevents or reduces the frequency, rate or extent of dipeptide transport.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-07-27T02:55:21Z					biological_process											owl:Class	
GO:0052542	biolink:NamedThing	defense response by callose deposition	Any process in which callose is transported to, and/or maintained in, a specific location during the defense response. Callose is a linear 1,3-beta-d-glucan formed from UDP-glucose and is found in certain plant cell walls.	tmpzr1t_l9r_go_relaxed.owl	callose deposition during defense response|callose localization during defense response													biological_process											owl:Class	
GO:0035939	biolink:NamedThing	microsatellite binding	Binding to a microsatellite, a repeat_region in DNA containing repeat units (2 to 4 base pairs) that is repeated multiple times in tandem.	tmpzr1t_l9r_go_relaxed.owl	variable number tandem repeat binding|VNTR binding|microsatellite DNA binding							bf	2011-07-20T01:26:26Z					molecular_function											owl:Class	
GO:0003696	biolink:NamedThing	satellite DNA binding	Binding to satellite DNA, the many tandem repeats (identical or related) of a short basic repeating unit; many have a base composition or other property different from the genome average that allows them to be separated from the bulk (main band) genomic DNA.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0009535	biolink:NamedThing	chloroplast thylakoid membrane	The pigmented membrane of a chloroplast thylakoid. An example of this component is found in Arabidopsis thaliana.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0008712	biolink:NamedThing	ADP-glyceromanno-heptose 6-epimerase activity	Catalysis of the reaction: ADP-D-glycero-D-manno-heptose = ADP-L-glycero-D-manno-heptose.	tmpzr1t_l9r_go_relaxed.owl	ADPglyceromanno-heptose 6-epimerase activity|ADP-L-glycero-D-manno-heptose 6-epimerase activity				EC:5.1.3.20|RHEA:17577|KEGG_REACTION:R05176|MetaCyc:5.1.3.20-RXN									molecular_function											owl:Class	
GO:1905518	biolink:NamedThing	regulation of presynaptic active zone assembly	Any process that modulates the frequency, rate or extent of presynaptic active zone assembly.	tmpzr1t_l9r_go_relaxed.owl	regulation of pre-synaptic active zone formation|regulation of presynaptic active zone formation|regulation of pre-synaptic active zone component formation|regulation of pre-synaptic active zone assembly|regulation of pre-synaptic active zone component assembly							rl	2016-10-01T09:37:51Z					biological_process											owl:Class	
GO:2001084	biolink:NamedThing	L-arabinofuranose binding	Binding to L-arabinofuranose.	tmpzr1t_l9r_go_relaxed.owl								jl	2011-09-15T01:33:53Z					molecular_function											owl:Class	
GO:0016409	biolink:NamedThing	palmitoyltransferase activity	Catalysis of the transfer of a palmitoyl (CH3-[CH2]14-CO-) group to an acceptor molecule.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-203567|Reactome:R-HSA-5686304									molecular_function											owl:Class	
GO:0000446	biolink:NamedThing	nucleoplasmic THO complex	The THO complex when it is acting as a nuclear complex that is required for transcription elongation through genes containing tandemly repeated DNA sequences. In S. cerevisiae, it is composed of four subunits: Hpr1, Tho2, Thp2, and Mft1, while the human complex is composed of 7 subunits.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:1900078	biolink:NamedThing	positive regulation of cellular response to insulin stimulus	Any process that activates or increases the frequency, rate or extent of cellular response to insulin stimulus.	tmpzr1t_l9r_go_relaxed.owl	activation of cellular response to insulin stimulus|upregulation of cellular response to insulin stimulus|up-regulation of cellular response to insulin stimulus|up regulation of cellular response to insulin stimulus							yaf	2012-01-31T11:24:30Z					biological_process											owl:Class	
GO:0090270	biolink:NamedThing	regulation of fibroblast growth factor production	Any process that modulates the rate, frequency or extent of the appearance of a fibroblast growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	tmpzr1t_l9r_go_relaxed.owl								tb	2010-02-05T02:33:33Z					biological_process											owl:Class	
GO:1904801	biolink:NamedThing	positive regulation of neuron remodeling	Any process that activates or increases the frequency, rate or extent of neuron remodeling.	tmpzr1t_l9r_go_relaxed.owl	up regulation of neuron remodeling|up-regulation of neuronal remodeling|upregulation of neuronal remodeling|upregulation of axon pruning|up regulation of axon pruning|activation of neuronal remodeling|activation of neuron remodeling|positive regulation of neuronal remodeling|activation of axon pruning|up regulation of neuronal remodeling|up-regulation of neuron remodeling|upregulation of neuron remodeling|positive regulation of axon pruning|up-regulation of axon pruning					cyy-1 in C. Elegans (P34624) in PMID:21609829 (inferred from mutant phenotype)		es	2015-11-09T13:47:07Z					biological_process											owl:Class	
GO:0001694	biolink:NamedThing	histamine biosynthetic process	The chemical reactions and pathways resulting in the formation of histamine, a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans.	tmpzr1t_l9r_go_relaxed.owl	histamine synthesis|histamine formation|histamine biosynthesis|histamine anabolism											GO:0001693		biological_process											owl:Class	
GO:0070103	biolink:NamedThing	regulation of interleukin-6-mediated signaling pathway	Any process that modulates the rate, frequency or extent of the series of molecular events generated as a consequence of interleukin-6-mediated binding to a cell surface receptor.	tmpzr1t_l9r_go_relaxed.owl	regulation of IL-6-mediated signaling pathway|regulation of interleukin-6-mediated signalling pathway													biological_process											owl:Class	
GO:0099544	biolink:NamedThing	perisynaptic space	The extracellular region immediately adjacent to to a synapse.	tmpzr1t_l9r_go_relaxed.owl	extrasynaptic space													cellular_component											owl:Class	
GO:0004565	biolink:NamedThing	beta-galactosidase activity	Catalysis of the hydrolysis of terminal, non-reducing beta-D-galactose residues in beta-D-galactosides.	tmpzr1t_l9r_go_relaxed.owl	trilactase activity|exo-(1->4)-beta-D-galactanase activity|lactose hydrolysis|beta-D-lactosidase activity|S 2107|hydrolact|sumiklat|beta-D-galactanase activity|lactozym|beta-D-galactoside galactohydrolase activity|beta-lactosidase activity|oryzatym|maxilact				Reactome:R-HSA-1606312|Reactome:R-HSA-9036061|Reactome:R-HSA-1630306|MetaCyc:BGALACT-PWY|Reactome:R-HSA-2090079|EC:3.2.1.23|Reactome:R-HSA-1793217|Reactome:R-HSA-1605624|MetaCyc:3.2.1.23-RXN|Reactome:R-HSA-2265534	Note that the inclusion of 'MetaCyc:BGALACT-PWY' is exceptional: normally MetaCyc pathway entries are database references for biological process terms, not molecular function terms. An exception was made in this case because the MetaCyc entry 'BGALACT-PWY' describes only one reaction, that catalyzed by beta-galactosidase.								molecular_function											owl:Class	
GO:0019506	biolink:NamedThing	phenylmercury acetate catabolic process	The chemical reactions and pathways resulting in the breakdown of phenylmercury acetate, an organomercurial compound composed of a mercury atom attached to a benzene ring and an acetate group.	tmpzr1t_l9r_go_relaxed.owl	phenylmercury acetate breakdown|phenylmercury acetate catabolism|phenylmercury acetate degradation				MetaCyc:P641-PWY									biological_process											owl:Class	
GO:0046412	biolink:NamedThing	phenylmercury acetate metabolic process	The chemical reactions and pathways involving phenylmercury acetate, an organomercurial compound composed of a mercury atom attached to a benzene ring and an acetate group.	tmpzr1t_l9r_go_relaxed.owl	phenylmercury acetate metabolism													biological_process											owl:Class	
GO:0042882	biolink:NamedThing	L-arabinose transmembrane transport	The process in which L-arabinose, the L-enantiomer of arabinose, is transported across a lipid bilayer, from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	L-arabinose transport													biological_process											owl:Class	
GO:0015751	biolink:NamedThing	arabinose transmembrane transport	The process in which arabinose, a pentose monosaccharide that occurs in both D and L configurations, is transported across a lipid bilayer, from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	arabinose transport													biological_process											owl:Class	
GO:0006124	biolink:NamedThing	ferredoxin metabolic process	The chemical reactions and pathways involving ferredoxin, any simple, nonenzymatic iron-sulfur protein that is characterized by having equal numbers of atoms of iron and labile sulfur. Iron and sulfur atoms are present in one or two clusters of two or four atoms of each.	tmpzr1t_l9r_go_relaxed.owl	ferredoxin metabolism													biological_process											owl:Class	
GO:0019659	biolink:NamedThing	glucose catabolic process to lactate	The anaerobic enzymatic chemical reactions and pathways resulting in the breakdown of glucose to lactate, and possibly ethanol, yielding energy in the form of adenosine triphosphate (ATP).	tmpzr1t_l9r_go_relaxed.owl	lactate fermentation|glucose fermentation to lactate				Wikipedia:Lactic_acid_fermentation									biological_process											owl:Class	
GO:0018776	biolink:NamedThing	trans-chloroacrylic acid dehalogenase activity	Catalysis of the reaction: trans-3-chloroacrylic acid + H2O = H+ + malonate semialdehyde.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0689									molecular_function											owl:Class	
GO:0047705	biolink:NamedThing	bilirubin oxidase activity	Catalysis of the reaction: 2 bilirubin + O(2) = 2 biliverdin + 2 H(2)O.	tmpzr1t_l9r_go_relaxed.owl	bilirubin:oxygen oxidoreductase activity|bilirubin oxidase M-1				MetaCyc:BILIRUBIN-OXIDASE-RXN|RHEA:20980|KEGG_REACTION:R02394|EC:1.3.3.5									molecular_function											owl:Class	
GO:0016634	biolink:NamedThing	oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces oxygen.	tmpzr1t_l9r_go_relaxed.owl					EC:1.3.3.-									molecular_function											owl:Class	
GO:0009189	biolink:NamedThing	deoxyribonucleoside diphosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of a deoxyribonucleoside diphosphate, a compound consisting of a nucleobase linked to a deoxyribose sugar esterified with diphosphate on the sugar.	tmpzr1t_l9r_go_relaxed.owl	deoxyribonucleoside diphosphate formation|deoxyribonucleoside diphosphate anabolism|deoxyribonucleoside diphosphate biosynthesis|deoxyribonucleoside diphosphate synthesis													biological_process											owl:Class	
GO:1904520	biolink:NamedThing	regulation of myofibroblast cell apoptotic process	Any process that modulates the frequency, rate or extent of myofibroblast cell apoptotic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of MFB apoptosis|regulation of MFB apoptotic process|regulation of myofibroblast cell apoptosis							sl	2015-07-29T15:52:14Z					biological_process											owl:Class	
GO:0019491	biolink:NamedThing	ectoine biosynthetic process	The chemical reactions and pathways resulting in the formation of ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidinecarboxylic acid), a tetrahydropyrimidine commonly synthesized by halophilic bacteria.	tmpzr1t_l9r_go_relaxed.owl	ectoine anabolism|ectoine synthesis|ectoine biosynthesis|ectoine formation				MetaCyc:P101-PWY									biological_process											owl:Class	
GO:0034331	biolink:NamedThing	cell junction maintenance	The organization process that preserves a cell junction in a stable functional or structural state. A cell junction is a specialized region of connection between two cells or between a cell and the extracellular matrix.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1905004	biolink:NamedThing	picolinic acid biosynthetic process	The chemical reactions and pathways resulting in the formation of picolinic acid.	tmpzr1t_l9r_go_relaxed.owl	picolinic acid formation|picolinate biosynthetic process|picolinic acid synthesis|picolinic acid anabolism|picolinic acid biosynthesis|picolinate biosynthesis							bf	2016-03-01T14:06:35Z					biological_process											owl:Class	
GO:1902472	biolink:NamedThing	regulation of mitotic cytokinesis, site selection	Any process that modulates the frequency, rate or extent of mitotic cytokinesis, site selection.	tmpzr1t_l9r_go_relaxed.owl								mah	2013-10-24T14:20:12Z					biological_process											owl:Class	
GO:0048807	biolink:NamedThing	female genitalia morphogenesis	The process in which the anatomical structures of female genitalia are generated and organized.	tmpzr1t_l9r_go_relaxed.owl	female genital morphogenesis													biological_process											owl:Class	
GO:0019319	biolink:NamedThing	hexose biosynthetic process	The chemical reactions and pathways resulting in the formation of hexose, any monosaccharide with a chain of six carbon atoms in the molecule.	tmpzr1t_l9r_go_relaxed.owl	hexose synthesis|hexose biosynthesis|hexose formation|hexose anabolism													biological_process											owl:Class	
GO:0023061	biolink:NamedThing	signal release	The process in which a signal is secreted or discharged into the extracellular medium from a cellular source.	tmpzr1t_l9r_go_relaxed.owl	signal secretion								2010-02-16T09:30:50Z					biological_process											owl:Class	
GO:1905243	biolink:NamedThing	cellular response to 3,3',5-triiodo-L-thyronine	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 3,3',5-triiodo-L-thyronine stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to Liothyronine|cellular response to Liothyroninum|cellular response to Liothyronin							sl	2016-06-08T17:42:12Z					biological_process											owl:Class	
GO:0106095	biolink:NamedThing	m7G(5')pppN diphosphatase complex	A homodimeric protein complex that catalyzes the reaction: 7-methylguanosine-5'-triphospho-5'-pholynucleotide + H20 = 7-methylguanosine-5'-phosphate + polynucleotide.	tmpzr1t_l9r_go_relaxed.owl	m7G(5')pppN pyrophosphatase enzyme|M(7)G(5')pppN pyrophosphatase enzyme|7-methylguanosine-5'-triphospho-5'-polynucleotide 7-methylguanosine-5'-phosphohydrolase enzyme|DCS1 decapping scavenger complex|m7G(5')pppN diphosphatase enzyme							hjd	2018-02-07T17:52:03Z					cellular_component											owl:Class	
GO:0004665	biolink:NamedThing	prephenate dehydrogenase (NADP+) activity	Catalysis of the reaction: NADP(+) + prephenate = (4-hydroxyphenyl)pyruvate + CO(2) + NADPH.	tmpzr1t_l9r_go_relaxed.owl	prephenate (nicotinamide adenine dinucleotide phosphate) dehydrogenase activity|prephenate:NADP+ oxidoreductase (decarboxylating)				EC:1.3.1.13|MetaCyc:PREPHENATE-DEHYDROGENASE-NADP+-RXN|KEGG_REACTION:R01730|RHEA:21640									molecular_function											owl:Class	
GO:0019411	biolink:NamedThing	aerobic respiration, using ferrous ions as electron donor	The metabolic process in which ferrous ions (Fe2+) are oxidized to ferric ions (Fe3+) to generate energy, coupled to the reduction of carbon dioxide.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1900987	biolink:NamedThing	ajmaline catabolic process	The chemical reactions and pathways resulting in the breakdown of ajmaline.	tmpzr1t_l9r_go_relaxed.owl	ajmaline catabolism|ajmaline breakdown|ajmaline degradation							yaf	2012-06-14T09:47:26Z					biological_process											owl:Class	
GO:0032109	biolink:NamedThing	positive regulation of response to nutrient levels	Any process that activates or increases the frequency, rate or extent of a response to nutrient levels.	tmpzr1t_l9r_go_relaxed.owl	stimulation of response to nutrient levels|up-regulation of response to nutrient levels|up regulation of response to nutrient levels|upregulation of response to nutrient levels|activation of response to nutrient levels													biological_process											owl:Class	
GO:0032107	biolink:NamedThing	regulation of response to nutrient levels	Any process that modulates the frequency, rate or extent of a response to nutrient levels.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0071348	biolink:NamedThing	cellular response to interleukin-11	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-11 stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to IL-11							mah	2009-12-11T02:49:29Z					biological_process											owl:Class	
GO:0071105	biolink:NamedThing	response to interleukin-11	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-11 stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to IL-11							mah	2009-11-09T12:52:51Z					biological_process											owl:Class	
GO:0022871	biolink:NamedThing	protein-N(PI)-phosphohistidine-sorbose phosphotransferase system transporter activity	Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + sorbose(out) = protein histidine + sorbose phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.	tmpzr1t_l9r_go_relaxed.owl	sorbose PTS transporter activity	https://github.com/geneontology/go-ontology/issues/17289			RHEA:49296|EC:2.7.1.206									molecular_function											owl:Class	
GO:0060498	biolink:NamedThing	retinoic acid receptor signaling pathway involved in lung bud formation	The series of molecular signals generated as a consequence of a retinoic acid receptor binding to one of its physiological ligands contributing to the formation of the primary lung bud.	tmpzr1t_l9r_go_relaxed.owl	retinoic acid receptor signalling pathway involved in lung bud formation													biological_process											owl:Class	
GO:1900225	biolink:NamedThing	regulation of NLRP3 inflammasome complex assembly	Any process that modulates the frequency, rate or extent of NLRP3 inflammasome complex assembly.	tmpzr1t_l9r_go_relaxed.owl	regulation of NALP3 inflammasome complex assembly|regulation of NLRP3 inflammasome activation							jl	2012-03-22T04:18:14Z					biological_process											owl:Class	
GO:0006555	biolink:NamedThing	methionine metabolic process	The chemical reactions and pathways involving methionine (2-amino-4-(methylthio)butanoic acid), a sulfur-containing, essential amino acid found in peptide linkage in proteins.	tmpzr1t_l9r_go_relaxed.owl	methionine and threonine metabolism|methionine metabolism|methionine and threonine metabolic process				UM-BBD_pathwayID:met									biological_process											owl:Class	
GO:0034696	biolink:NamedThing	response to prostaglandin F	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin F stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to prostaglandin F stimulus													biological_process											owl:Class	
GO:0034694	biolink:NamedThing	response to prostaglandin	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to prostaglandin stimulus													biological_process											owl:Class	
GO:1904924	biolink:NamedThing	negative regulation of mitophagy in response to mitochondrial depolarization	Any process that stops, prevents or reduces the frequency, rate or extent of mitophagy in response to mitochondrial depolarization.	tmpzr1t_l9r_go_relaxed.owl	downregulation of mitophagy in response to mitochondrial depolarization|down-regulation of mitophagy in response to mitochondrial depolarization|down regulation of mitophagy in response to mitochondrial depolarization|inhibition of mitophagy in response to mitochondrial depolarization							pad	2016-01-26T11:23:58Z					biological_process											owl:Class	
GO:1990447	biolink:NamedThing	U2 snRNP binding	Binding to a U2 small nuclear ribonucleoprotein particle.	tmpzr1t_l9r_go_relaxed.owl								mah	2014-08-06T09:33:38Z					molecular_function											owl:Class	
GO:0070990	biolink:NamedThing	snRNP binding	Binding to a small nuclear ribonucleoprotein particle.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-10-29T03:54:25Z					molecular_function											owl:Class	
GO:0034263	biolink:NamedThing	positive regulation of autophagy in response to ER overload	The process in which the accumulation of misfolded proteins in the endoplasmic reticulum triggers a response that positively regulates autophagy.	tmpzr1t_l9r_go_relaxed.owl	autophagy in response to endoplasmic reticulum overload|autophagy in response to ER stress													biological_process											owl:Class	
GO:0010508	biolink:NamedThing	positive regulation of autophagy	Any process that activates, maintains or increases the rate of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0050541	biolink:NamedThing	beta,beta-carotene-9',10'-dioxygenase activity	Catalysis of the reaction: beta-carotene + O2 = beta-apo-10'-carotenal + beta-ionone.	tmpzr1t_l9r_go_relaxed.owl	b,b-carotene-9',10'-dioxygenase activity													molecular_function											owl:Class	
GO:1905840	biolink:NamedThing	positive regulation of telomeric D-loop disassembly	Any process that activates or increases the frequency, rate or extent of telomeric D-loop disassembly.	tmpzr1t_l9r_go_relaxed.owl	up regulation of telomeric D-loop disassembly|upregulation of telomeric D-loop disassembly|up-regulation of telomeric D-loop disassembly|activation of telomeric D-loop disassembly							nc	2017-01-18T11:01:55Z					biological_process											owl:Class	
GO:0035207	biolink:NamedThing	negative regulation of hemocyte proliferation	Any process that stops, prevents or reduces the rate or extent of hemocyte proliferation. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. An example of this is found in Drosophila melanogaster.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of arthropod blood cell proliferation|down-regulation of hemocyte proliferation|down regulation of hemocyte proliferation|inhibition of hemocyte proliferation|downregulation of hemocyte proliferation													biological_process											owl:Class	
GO:0006686	biolink:NamedThing	sphingomyelin biosynthetic process	The chemical reactions and pathways resulting in the formation of sphingomyelin, N-acyl-4-sphingenyl-1-O-phosphorylcholine.	tmpzr1t_l9r_go_relaxed.owl	sphingomyelin synthesis|sphingomyelin anabolism|sphingomyelin biosynthesis|sphingomyelin formation													biological_process											owl:Class	
GO:0051142	biolink:NamedThing	positive regulation of NK T cell proliferation	Any process that activates or increases the frequency, rate or extent of natural killer T cell proliferation.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of NT cell proliferation|stimulation of NK T cell proliferation|activation of NK T cell proliferation|up-regulation of NK T cell proliferation|positive regulation of NKT cell proliferation|upregulation of NK T cell proliferation|positive regulation of NK T lymphocyte proliferation|positive regulation of natural killer T cell proliferation|positive regulation of natural T cell proliferation|up regulation of NK T cell proliferation|positive regulation of NK T-lymphocyte proliferation|positive regulation of NK T-cell proliferation													biological_process											owl:Class	
GO:0008030	biolink:NamedThing	neuronal pentraxin receptor activity	Combining with a neuronal pentraxin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	neuronal pentaxin receptor													molecular_function											owl:Class	
GO:0000958	biolink:NamedThing	mitochondrial mRNA catabolic process	The chemical reactions and pathways resulting in the breakdown of mRNA transcribed from the mitochondrial genome and occurring in the mitochondrion.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0006274	biolink:NamedThing	DNA replication termination	The process in which DNA replication at a replication fork ceases; occurs when the replication fork reaches a specific termination site or when two replication forks meet.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0033463	biolink:NamedThing	GGA codon-amino acid adaptor activity	A triplet codon-amino acid adaptor activity that recognizes a GGA codon.	tmpzr1t_l9r_go_relaxed.owl	glycine tRNA					Note that in the standard genetic code, GGA codes for glycine.								molecular_function											owl:Class	
GO:0052575	biolink:NamedThing	carbohydrate localization	Any process in which a carbohydrate is transported to, or maintained in, a specific location. Carbohydrates are any of a group of organic compounds based of the general formula Cx(H2O)y.	tmpzr1t_l9r_go_relaxed.owl	carbohydrate localisation								2010-07-23T04:08:13Z					biological_process											owl:Class	
GO:0043873	biolink:NamedThing	pyruvate-flavodoxin oxidoreductase activity	Catalysis of the reaction: pyruvate + CoA + oxidized flavodoxin = acetyl-CoA + CO2 + reduced flavodoxin.	tmpzr1t_l9r_go_relaxed.owl	NifJ|pyruvate:flavodoxin oxidoreductase activity				RHEA:44140|MetaCyc:PYFLAVOXRE-RXN									molecular_function											owl:Class	
GO:1900520	biolink:NamedThing	positive regulation of response to pullulan	Any process that activates or increases the frequency, rate or extent of response to pullulan.	tmpzr1t_l9r_go_relaxed.owl	up regulation of response to pullulan|up-regulation of response to pullulan|upregulation of response to pullulan|activation of response to pullulan							tt	2012-05-02T04:12:19Z					biological_process											owl:Class	
GO:1904954	biolink:NamedThing	canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation	Any canonical Wnt signaling pathway that is involved in midbrain dopaminergic neuron differentiation.	tmpzr1t_l9r_go_relaxed.owl	Wnt receptor signalling pathway through beta-catenin involved in DA neurogenesis from midbrain floor plate|Wnt receptor signalling pathway through beta-catenin involved in midbrain dopaminergic neuron differentiation|Wnt receptor signalling pathway through beta-catenin involved in midbrain DA neurogenesis|Wnt receptor signaling pathway via beta-catenin involved in midbrain DA neurogenesis|canonical Wnt receptor signaling pathway involved in DA neurogenesis from midbrain floor plate|frizzled-1 receptor signaling pathway involved in midbrain dopaminergic neuron production|canonical Wnt-activated signaling pathway involved in midbrain DA neurogenesis|canonical Wnt receptor signaling pathway involved in mDA neuron differentiation|Wnt receptor signaling pathway via beta-catenin involved in midbrain dopaminergic neuron differentiation|canonical Wnt signaling pathway involved in midbrain dopaminergic neuron production|frizzled-1 receptor signaling pathway involved in DA neurogenesis from midbrain floor plate|Wnt receptor signaling pathway through beta-catenin involved in mDA neuron differentiation|canonical Wnt-activated signaling pathway involved in midbrain dopaminergic neuron differentiation|canonical Wnt signaling pathway involved in DA neurogenesis from midbrain floor plate|Wnt receptor signaling pathway through beta-catenin involved in midbrain dopaminergic neuron production|canonical Wnt-activated signaling pathway involved in midbrain dopaminergic neuron production|canonical Wnt signaling pathway involved in mDA neuron differentiation|Wnt receptor signaling pathway via beta-catenin involved in mDA neuron differentiation|Wnt receptor signaling pathway via beta-catenin involved in midbrain dopaminergic neuron production|frizzled-1 receptor signaling pathway involved in mDA neuron differentiation|canonical Wnt receptor signaling pathway involved in midbrain dopaminergic neuron differentiation|canonical Wnt-activated signaling pathway involved in DA neurogenesis from midbrain floor plate|Wnt receptor signaling pathway through beta-catenin involved in DA neurogenesis from midbrain floor plate|frizzled-1 receptor signaling pathway involved in midbrain dopaminergic neuron differentiation|canonical Wnt receptor signaling pathway involved in midbrain DA neurogenesis|canonical Wnt receptor signaling pathway involved in midbrain dopaminergic neuron production|frizzled-1 receptor signaling pathway involved in midbrain DA neurogenesis|Wnt receptor signalling pathway through beta-catenin involved in midbrain dopaminergic neuron production|Wnt receptor signaling pathway through beta-catenin involved in midbrain DA neurogenesis|Wnt receptor signalling pathway through beta-catenin involved in mDA neuron differentiation|canonical Wnt-mediated midbrain DA neuron differentiation|canonical Wnt signaling pathway involved in midbrain DA neurogenesis|Wnt receptor signaling pathway via beta-catenin involved in DA neurogenesis from midbrain floor plate|Wnt receptor signaling pathway through beta-catenin involved in midbrain dopaminergic neuron differentiation|canonical Wnt-activated signaling pathway involved in mDA neuron differentiation							bf	2016-02-09T11:04:46Z					biological_process											owl:Class	
GO:1904953	biolink:NamedThing	Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation	Any Wnt signaling pathway that is involved in midbrain dopaminergic neuron differentiation.	tmpzr1t_l9r_go_relaxed.owl	Wnt receptor signalling pathway involved in midbrain DA neurogenesis|Wnt-activated signaling pathway involved in mDA neuron differentiation|Wg signalling pathway involved in DA neurogenesis from midbrain floor plate|Wg signalling pathway involved in midbrain dopaminergic neuron differentiation|Wnt receptor signalling pathway involved in midbrain dopaminergic neuron production|Wnt-activated signaling pathway involved in DA neurogenesis from midbrain floor plate|Wnt receptor signaling pathway involved in mDA neuron differentiation|Wingless signaling pathway involved in DA neurogenesis from midbrain floor plate|Wg signalling pathway involved in midbrain dopaminergic neuron production|frizzled signaling pathway involved in DA neurogenesis from midbrain floor plate|Wnt receptor signalling pathway involved in DA neurogenesis from midbrain floor plate|Wg signaling pathway involved in midbrain DA neurogenesis|Wnt-activated signaling pathway involved in midbrain dopaminergic neuron differentiation|Wg signaling pathway involved in DA neurogenesis from midbrain floor plate|Wingless signalling pathway involved in mDA neuron differentiation|Wnt receptor signalling pathway involved in mDA neuron differentiation|frizzled signalling pathway involved in midbrain DA neurogenesis|Wnt receptor signalling pathway involved in midbrain dopaminergic neuron differentiation|Wg signaling pathway involved in midbrain dopaminergic neuron production|Wg signalling pathway involved in mDA neuron differentiation|Wnt receptor signaling pathway involved in DA neurogenesis from midbrain floor plate|Wingless signalling pathway involved in midbrain dopaminergic neuron production|frizzled signaling pathway involved in midbrain dopaminergic neuron production|Wingless signaling pathway involved in mDA neuron differentiation|Wingless signalling pathway involved in DA neurogenesis from midbrain floor plate|frizzled signaling pathway involved in midbrain dopaminergic neuron differentiation|frizzled signalling pathway involved in midbrain dopaminergic neuron differentiation|Wg signalling pathway involved in midbrain DA neurogenesis|frizzled signalling pathway involved in midbrain dopaminergic neuron production|Wnt signaling pathway involved in midbrain DA neurogenesis|Wnt receptor signaling pathway involved in midbrain DA neurogenesis|Wingless signaling pathway involved in midbrain DA neurogenesis|Wnt-activated signaling pathway involved in midbrain dopaminergic neuron production|Wingless signaling pathway involved in midbrain dopaminergic neuron production|Wg signaling pathway involved in midbrain dopaminergic neuron differentiation|Wnt-mediated midbrain DA neuron differentiation|Wnt signaling pathway involved in DA neurogenesis from midbrain floor plate|Wnt receptor signaling pathway involved in midbrain dopaminergic neuron production|Wingless signalling pathway involved in midbrain DA neurogenesis|frizzled signaling pathway involved in mDA neuron differentiation|Wnt signaling pathway involved in midbrain dopaminergic neuron production|Wingless signalling pathway involved in midbrain dopaminergic neuron differentiation|Wingless signaling pathway involved in midbrain dopaminergic neuron differentiation|frizzled signalling pathway involved in DA neurogenesis from midbrain floor plate|Wg signaling pathway involved in mDA neuron differentiation|Wnt-activated signaling pathway involved in midbrain DA neurogenesis|frizzled signaling pathway involved in midbrain DA neurogenesis|Wnt signaling pathway involved in mDA neuron differentiation|Wnt receptor signaling pathway involved in midbrain dopaminergic neuron differentiation|frizzled signalling pathway involved in mDA neuron differentiation							bf	2016-02-08T12:02:07Z					biological_process											owl:Class	
GO:0016631	biolink:NamedThing	enoyl-[acyl-carrier-protein] reductase activity	Catalysis of the reaction: acyl-[acyl-carrier protein] + NAD(P)+ = trans-2,3-dehydroacyl-[acyl-carrier protein] + NAD(P)H + H+.	tmpzr1t_l9r_go_relaxed.owl	enoyl-ACP reductase activity|enoyl-[acyl-carrier protein] reductase activity|enoyl-acyl carrier protein reductase|acyl-ACP dehydrogenase activity				MetaCyc:RXN1G-3993|MetaCyc:RXN1G-45|MetaCyc:RXN1G-4140|MetaCyc:RXN1G-2527|Wikipedia:Enoyl-acyl_carrier_protein_reductase|MetaCyc:RXN1G-2544|MetaCyc:RXN1G-3256|MetaCyc:1.3.1.39-RXN|MetaCyc:RXN1G-3232|MetaCyc:RXN1G-3641|MetaCyc:1.3.1.10-RXN|MetaCyc:RXN1G-3667|MetaCyc:RXN1G-3613|EC:1.3.1.9									molecular_function											owl:Class	
GO:0048860	biolink:NamedThing	glioblast division	The process resulting in the physical partitioning and separation of a glioblast into daughter cells.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0038127	biolink:NamedThing	ERBB signaling pathway	A series of molecular signals initiated by binding of a ligand to a member of the ERBB family of receptor tyrosine kinases on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.	tmpzr1t_l9r_go_relaxed.owl	ErbB signaling|EGF receptor family signaling pathway|EGFR family signaling pathway|ERBB signalling pathway							bf	2012-03-30T09:23:01Z					biological_process											owl:Class	
GO:0060697	biolink:NamedThing	positive regulation of phospholipid catabolic process	Any process that increases the rate, frequency, or extent of phospholipid catabolism, the chemical reactions and pathways resulting in the breakdown of phospholipids, any lipid containing phosphoric acid as a mono- or diester.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-06-08T02:28:38Z					biological_process											owl:Class	
GO:0007297	biolink:NamedThing	ovarian follicle cell migration	The directed movement of an ovarian follicle cell that takes place during oogenesis. During egg chamber formation, follicle cells migrate to envelop the germ-line cysts and move in between cysts. At stage 10B, follicle cells migrate centripetally between the nurse cells and the oocyte, enclosing the anterior of the egg. An example of this is found in Drosophila melanogaster.	tmpzr1t_l9r_go_relaxed.owl	follicle cell migration													biological_process											owl:Class	
GO:1902162	biolink:NamedThing	regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator	Any process that modulates the frequency, rate or extent of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator.	tmpzr1t_l9r_go_relaxed.owl								lb	2013-05-22T12:39:18Z					biological_process											owl:Class	
GO:0150045	biolink:NamedThing	regulation of synaptic signaling by nitric oxide	Any process that modulates the frequency, rate or extent of synaptic signaling by nitric oxide.	tmpzr1t_l9r_go_relaxed.owl								bc	2018-04-23T09:42:25Z					biological_process											owl:Class	
GO:0030565	biolink:NamedThing	snRNA pseudouridylation guide activity	Activity that provides specificity to a pseudouridine synthetase by using base complementarity to guide site-specific pseudouridylations to a small nuclear RNA molecule.	tmpzr1t_l9r_go_relaxed.owl						Note that this term describes the activity of a nucleic acid, usually RNA, gene product that interacts with other RNA molecules via base pairing; it should not be used to annotate proteins. Note that this term may be useful for annotating snoRNAs.								molecular_function											owl:Class	
GO:0050972	biolink:NamedThing	detection of mechanical stimulus involved in echolocation	The series of events involved in echolocation in which a mechanical stimulus is received and converted into a molecular signal. The stimulus is in the form of a reflected sound wave (an echo), which the organism uses to determine the distance to the object that reflected the sound wave.	tmpzr1t_l9r_go_relaxed.owl	echolocation, sensory transduction of mechanical stimulus|echolocation, detection of mechanical stimulus|echolocation, sensory detection of mechanical stimulus|sensory detection of mechanical stimulus during echolocation|sensory transduction of mechanical stimulus during echolocation													biological_process											owl:Class	
GO:0050974	biolink:NamedThing	detection of mechanical stimulus involved in sensory perception	The series of events in which a mechanical stimulus is received and converted into a molecular signal as part of sensory perception.	tmpzr1t_l9r_go_relaxed.owl	sensory transduction of mechanical stimulus|sensory detection of mechanical stimulus|sensory transduction of mechanical stimulus during sensory perception|sensory perception, sensory detection of mechanical stimulus|sensory perception, sensory transduction of mechanical stimulus|sensory detection of mechanical stimulus during sensory perception													biological_process											owl:Class	
GO:0052692	biolink:NamedThing	raffinose alpha-galactosidase activity	Catalysis of the reaction: raffinose + H2O = alpha-D-galactose + sucrose.	tmpzr1t_l9r_go_relaxed.owl	raffinose galactohydrolase activity|alkaline alpha-galactosidase activity|raffinose-specific alkaline alpha-galactosidase activity				MetaCyc:RXN-11502|EC:3.2.1.22|KEGG_REACTION:R01103									molecular_function											owl:Class	
GO:0004557	biolink:NamedThing	alpha-galactosidase activity	Catalysis of the hydrolysis of terminal, non-reducing alpha-D-galactose residues in alpha-D-galactosides, including galactose oligosaccharides, galactomannans and galactohydrolase.	tmpzr1t_l9r_go_relaxed.owl	alpha-D-galactosidase activity|alpha-galactoside galactohydrolase activity|alpha-D-galactoside galactohydrolase activity|alpha-galactosidase A|melibiase activity				RHEA:28663|EC:3.2.1.22|MetaCyc:ALPHAGALACTOSID-RXN|Reactome:R-HSA-1605736									molecular_function											owl:Class	
GO:0010387	biolink:NamedThing	COP9 signalosome assembly	The aggregation, arrangement and bonding together of a set of components to form a COP9 signalosome.	tmpzr1t_l9r_go_relaxed.owl	signalosome assembly													biological_process											owl:Class	
GO:1990643	biolink:NamedThing	cellular response to granulocyte colony-stimulating factor	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a granulocyte colony-stimulating factor stimulus.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-02-11T19:22:44Z					biological_process											owl:Class	
GO:0061696	biolink:NamedThing	pituitary gonadotropin complex	A protein complex that is a protein hormone secreted by gonadotrope cells of the anterior pituitary of vertebrates. capable of regulating normal growth, sexual development, and reproductive function.	tmpzr1t_l9r_go_relaxed.owl								dph	2015-05-06T13:11:18Z					cellular_component											owl:Class	
GO:1900559	biolink:NamedThing	austinol catabolic process	The chemical reactions and pathways resulting in the breakdown of austinol.	tmpzr1t_l9r_go_relaxed.owl	austinol breakdown|austinol catabolism|austinol degradation							di	2012-05-15T06:27:22Z					biological_process											owl:Class	
GO:1900558	biolink:NamedThing	austinol metabolic process	The chemical reactions and pathways involving austinol.	tmpzr1t_l9r_go_relaxed.owl	austinol metabolism							di	2012-05-15T06:26:58Z					biological_process											owl:Class	
GO:0046389	biolink:NamedThing	deoxyribose 5-phosphate metabolic process	The chemical reactions and pathways involving deoxyribose 5-phosphate, the phosphorylated sugar 5-phospho-2-deoxyribose.	tmpzr1t_l9r_go_relaxed.owl	deoxyribose 5-phosphate metabolism													biological_process											owl:Class	
GO:0043654	biolink:NamedThing	recognition of apoptotic cell	The process in which a cell interprets signals (in the form of specific proteins and lipids) on the surface of a dying cell which it will engulf and remove by phagocytosis.	tmpzr1t_l9r_go_relaxed.owl	detection of apoptotic cell corpse|recognition of cell corpse|recognition of apoptotic cell corpse|detection of cell corpse|detection of apoptotic cell													biological_process											owl:Class	
GO:0006910	biolink:NamedThing	phagocytosis, recognition	The initial step in phagocytosis involving adhesion to bacteria, immune complexes and other particulate matter, or an apoptotic cell and based on recognition of factors such as bacterial cell wall components, opsonins like complement and antibody or protein receptors and lipids like phosphatidyl serine, and leading to intracellular signaling in the phagocytosing cell.	tmpzr1t_l9r_go_relaxed.owl	recognition of phagocytosed substance by phagocytic cell					Note that cell surface molecules involved in the direct binding of bacteria may be also annotated to the molecular function term 'bacterial cell surface binding ; GO:0051635'. Note that cell surface molecules involved in the direct binding to opsonins such as complement components or antibodies may be also annotated to the term 'opsonin binding ; GO:0001846'.								biological_process											owl:Class	
GO:0009183	biolink:NamedThing	purine deoxyribonucleoside diphosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of purine deoxyribonucleoside diphosphate, a compound consisting of a purine base linked to a deoxyribose sugar esterified with diphosphate on the sugar.	tmpzr1t_l9r_go_relaxed.owl	purine deoxyribonucleoside diphosphate biosynthesis|purine deoxyribonucleoside diphosphate synthesis|purine deoxyribonucleoside diphosphate anabolism|purine deoxyribonucleoside diphosphate formation													biological_process											owl:Class	
GO:0042859	biolink:NamedThing	chrysobactin catabolic process	The chemical reactions and pathways resulting in the breakdown of the siderophore chrysobactin (alpha-N-(2,3-dihydroxybenzoyl)-D-lysyl-L-serine).	tmpzr1t_l9r_go_relaxed.owl	chrysobactin breakdown|chrysobactin degradation|chrysobactin catabolism													biological_process											owl:Class	
GO:0031699	biolink:NamedThing	beta-3 adrenergic receptor binding	Binding to a beta-3 adrenergic receptor.	tmpzr1t_l9r_go_relaxed.owl	beta-3 adrenergic receptor ligand													molecular_function											owl:Class	
GO:1905283	biolink:NamedThing	negative regulation of epidermal growth factor receptor signaling pathway involved in heart process	Any process that stops, prevents or reduces the frequency, rate or extent of epidermal growth factor receptor signaling pathway involved in heart process.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of EGF receptor signaling pathway involved in heart process|inhibition of EGF receptor signalling pathway involved in heart process|downregulation of EGFR signaling pathway involved in cardiac process|down regulation of epidermal growth factor receptor signaling pathway involved in heart process|inhibition of epidermal growth factor receptor signaling pathway involved in cardiac process|negative regulation of epidermal growth factor receptor signalling pathway involved in cardiac process|downregulation of ERBB1 signaling pathway involved in heart process|downregulation of epidermal growth factor receptor signalling pathway involved in heart process|down-regulation of receptor tyrosine-protein kinase erbB-1 signaling pathway involved in cardiac process|down-regulation of ERBB1 signaling pathway involved in heart process|down regulation of EGF receptor signalling pathway involved in cardiac process|inhibition of EGF receptor signalling pathway involved in cardiac process|inhibition of epidermal growth factor receptor signalling pathway involved in cardiac process|downregulation of EGFR signaling pathway involved in heart process|down regulation of ERBB1 signaling pathway involved in heart process|inhibition of receptor tyrosine-protein kinase erbB-1 signaling pathway involved in heart process|down regulation of epidermal growth factor receptor signaling pathway involved in cardiac process|inhibition of ERBB1 signaling pathway involved in cardiac process|down-regulation of epidermal growth factor receptor signaling pathway involved in cardiac process|downregulation of receptor tyrosine-protein kinase erbB-1 signaling pathway involved in heart process|down-regulation of receptor tyrosine-protein kinase erbB-1 signaling pathway involved in heart process|negative regulation of EGF receptor signalling pathway involved in cardiac process|down-regulation of EGFR signaling pathway involved in heart process|downregulation of EGF receptor signaling pathway involved in cardiac process|negative regulation of EGF receptor signalling pathway involved in heart process|downregulation of ERBB1 signaling pathway involved in cardiac process|inhibition of EGFR signaling pathway involved in cardiac process|down regulation of EGF receptor signaling pathway involved in heart process|down regulation of ERBB1 signaling pathway involved in cardiac process|negative regulation of EGF receptor signaling pathway involved in cardiac process|negative regulation of receptor tyrosine-protein kinase erbB-1 signaling pathway involved in heart process|downregulation of epidermal growth factor receptor signaling pathway involved in cardiac process|down-regulation of epidermal growth factor receptor signaling pathway involved in heart process|inhibition of EGFR signaling pathway involved in heart process|negative regulation of EGFR signaling pathway involved in cardiac process|down regulation of epidermal growth factor receptor signalling pathway involved in heart process|negative regulation of receptor tyrosine-protein kinase erbB-1 signaling pathway involved in cardiac process|down-regulation of epidermal growth factor receptor signalling pathway involved in cardiac process|down-regulation of EGF receptor signaling pathway involved in cardiac process|negative regulation of ERBB1 signaling pathway involved in heart process|downregulation of EGF receptor signalling pathway involved in heart process|negative regulation of ERBB1 signaling pathway involved in cardiac process|down regulation of receptor tyrosine-protein kinase erbB-1 signaling pathway involved in heart process|downregulation of epidermal growth factor receptor signalling pathway involved in cardiac process|inhibition of ERBB1 signaling pathway involved in heart process|inhibition of EGF receptor signaling pathway involved in cardiac process|downregulation of epidermal growth factor receptor signaling pathway involved in heart process|inhibition of epidermal growth factor receptor signaling pathway involved in heart process|inhibition of EGF receptor signaling pathway involved in heart process|down-regulation of EGF receptor signalling pathway involved in cardiac process|down-regulation of ERBB1 signaling pathway involved in cardiac process|downregulation of EGF receptor signalling pathway involved in cardiac process|down regulation of epidermal growth factor receptor signalling pathway involved in cardiac process|down regulation of EGFR signaling pathway involved in heart process|downregulation of receptor tyrosine-protein kinase erbB-1 signaling pathway involved in cardiac process|negative regulation of epidermal growth factor receptor signaling pathway involved in cardiac process|inhibition of receptor tyrosine-protein kinase erbB-1 signaling pathway involved in cardiac process|down regulation of receptor tyrosine-protein kinase erbB-1 signaling pathway involved in cardiac process|down-regulation of EGF receptor signalling pathway involved in heart process|negative regulation of EGF receptor signaling pathway involved in heart process|inhibition of epidermal growth factor receptor signalling pathway involved in heart process|downregulation of EGF receptor signaling pathway involved in heart process|down regulation of EGFR signaling pathway involved in cardiac process|negative regulation of epidermal growth factor receptor signalling pathway involved in heart process|down-regulation of EGFR signaling pathway involved in cardiac process|down regulation of EGF receptor signaling pathway involved in cardiac process|down regulation of EGF receptor signalling pathway involved in heart process|down-regulation of epidermal growth factor receptor signalling pathway involved in heart process|negative regulation of EGFR signaling pathway involved in heart process							bc	2016-06-20T14:40:49Z					biological_process											owl:Class	
GO:0000322	biolink:NamedThing	storage vacuole	A vacuole that functions primarily in the storage of materials, including nutrients, pigments, waste products, and small molecules.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0070204	biolink:NamedThing	2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase activity	Catalysis of the reaction: 2-oxoglutarate + H(+) + isochorismate = 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1-carboxylate + CO(2).	tmpzr1t_l9r_go_relaxed.owl	SEPHCHC synthase activity|MenD				MetaCyc:2.5.1.64-RXN|EC:2.2.1.9|RHEA:25593|KEGG_REACTION:R08165	Note that this function was formerly EC:4.1.3.18.								molecular_function											owl:Class	
GO:1901945	biolink:NamedThing	miltiradiene catabolic process	The chemical reactions and pathways resulting in the breakdown of miltiradiene.	tmpzr1t_l9r_go_relaxed.owl	miltiradiene degradation|miltiradiene breakdown|miltiradiene catabolism							ms	2013-02-18T15:50:27Z					biological_process											owl:Class	
GO:1901944	biolink:NamedThing	miltiradiene metabolic process	The chemical reactions and pathways involving miltiradiene.	tmpzr1t_l9r_go_relaxed.owl	miltiradiene metabolism							ms	2013-02-18T15:50:23Z					biological_process											owl:Class	
GO:0140195	biolink:NamedThing	positive regulation of adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in heart process	Any process that activates or increases the frequency, rate or extent of an adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in some heart process.	tmpzr1t_l9r_go_relaxed.owl								pg	2018-02-15T19:13:11Z					biological_process											owl:Class	
GO:0071879	biolink:NamedThing	positive regulation of adenylate cyclase-activating adrenergic receptor signaling pathway	Any process that activates or increases the frequency, rate or extent of the adenylate cyclase-activating adrenergic receptor protein signaling pathway. An adrenergic receptor signaling pathway is the series of molecular signals generated as a consequence of an adrenergic receptor binding to one of its physiological ligands.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of adrenergic receptor signalling pathway|positive regulation of adrenergic receptor signaling pathway							mah	2010-09-13T04:15:57Z					biological_process											owl:Class	
GO:1900632	biolink:NamedThing	tridecane biosynthetic process	The chemical reactions and pathways resulting in the formation of tridecane.	tmpzr1t_l9r_go_relaxed.owl	tridecane synthesis|tridecane anabolism|tridecane biosynthesis|tridecane formation							tt	2012-05-21T06:41:37Z					biological_process											owl:Class	
GO:0102065	biolink:NamedThing	patchoulene synthase activity	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate <=> diphosphoric acid + gamma-patchoulene.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-10602									molecular_function											owl:Class	
GO:0050130	biolink:NamedThing	N-methyl-2-oxoglutaramate hydrolase activity	Catalysis of the reaction: N-methyl-2-oxoglutaramate + H(2)O = 2-oxoglutarate + methylammonium.	tmpzr1t_l9r_go_relaxed.owl	N-methyl-2-oxoglutaramate methylamidohydrolase activity|5-hydroxy-N-methylpyroglutamate synthase activity				EC:3.5.1.36|MetaCyc:N-METHYL-2-OXOGLUTARAMATE-HYDROLASE-RXN|RHEA:24108|KEGG_REACTION:R01587									molecular_function											owl:Class	
GO:0003427	biolink:NamedThing	regulation of cytoskeleton polarization involved in growth plate cartilage chondrocyte division	The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell that modulates the rate, frequency, or extent of the polarization of cytoskeletal structures in a growth plate cartilage chondrocyte. This process results in the oriented division of the cell.	tmpzr1t_l9r_go_relaxed.owl	regulation of cytoskeleton polarization involved in growth plate cartilage chondrocyte division by planar cell polarity pathway							dph	2009-12-22T11:43:29Z					biological_process											owl:Class	
GO:0010121	biolink:NamedThing	arginine catabolic process to proline via ornithine	The chemical reactions and pathways resulting in the breakdown of arginine into other compounds, including proline, via ornithine.	tmpzr1t_l9r_go_relaxed.owl	arginine degradation to proline via ornithine|arginine breakdown to proline via ornithine				MetaCyc:ARGORNPROST-PWY									biological_process											owl:Class	
GO:0019493	biolink:NamedThing	arginine catabolic process to proline	The chemical reactions and pathways resulting in the breakdown of arginine into other compounds, including proline.	tmpzr1t_l9r_go_relaxed.owl	arginine degradation to proline|arginine breakdown to proline				MetaCyc:ARG-PRO-PWY									biological_process											owl:Class	
GO:0102470	biolink:NamedThing	6C-naringenin dibenzoylmethane tautomer glucosyltransferase activity	Catalysis of the reaction: 2,4,4',6-tetrahydroxydibenzoylmethane + UDP-alpha-D-glucose <=> 6C-glucosyl-2-hydroxynaringenin + UDP + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-14075									molecular_function											owl:Class	
GO:1905046	biolink:NamedThing	positive regulation of Schwann cell proliferation involved in axon regeneration	Any process that activates or increases the frequency, rate or extent of Schwann cell proliferation involved in axon regeneration.	tmpzr1t_l9r_go_relaxed.owl	upregulation of Schwann cell proliferation involved in axon regeneration|up-regulation of Schwann cell proliferation involved in axon regeneration|activation of Schwann cell proliferation involved in axon regeneration|up regulation of Schwann cell proliferation involved in axon regeneration							rph	2016-03-11T14:47:54Z					biological_process											owl:Class	
GO:0002808	biolink:NamedThing	regulation of antibacterial peptide biosynthetic process	Any process that modulates the frequency, rate, or extent of antibacterial peptide biosynthesis.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0002786	biolink:NamedThing	regulation of antibacterial peptide production	Any process that modulates the frequency, rate, or extent of antibacterial peptide production.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0007179	biolink:NamedThing	transforming growth factor beta receptor signaling pathway	A series of molecular signals initiated by the binding of an extracellular ligand to a transforming growth factor beta receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.	tmpzr1t_l9r_go_relaxed.owl	TGF-beta receptor signalling pathway|TGF-beta receptor signaling pathway|transforming growth factor beta receptor signalling pathway|TGFbeta receptor signaling pathway|TGFbeta receptor signalling pathway													biological_process											owl:Class	
GO:0072118	biolink:NamedThing	pronephros structural organization	The process that contributes to the act of creating the structural organization of the pronephros. This process pertains to the physical shaping of a rudimentary structure. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life.	tmpzr1t_l9r_go_relaxed.owl	pronephros structural organisation|pronephric kidney structural organization							mah	2010-02-22T11:21:38Z					biological_process											owl:Class	
GO:1905407	biolink:NamedThing	regulation of creatine transmembrane transporter activity	Any process that modulates the frequency, rate or extent of creatine transmembrane transporter activity.	tmpzr1t_l9r_go_relaxed.owl								bc	2016-08-25T15:08:48Z					biological_process											owl:Class	
GO:0033403	biolink:NamedThing	UUA codon-amino acid adaptor activity	A triplet codon-amino acid adaptor activity that recognizes a UUA codon.	tmpzr1t_l9r_go_relaxed.owl	TTA codon-amino acid adaptor activity|leucine tRNA					Note that in the standard genetic code, TTA codes for leucine.								molecular_function											owl:Class	
GO:1904727	biolink:NamedThing	negative regulation of replicative senescence	Any process that stops, prevents or reduces the frequency, rate or extent of replicative senescence.	tmpzr1t_l9r_go_relaxed.owl	down regulation of replicative senescence|inhibition of replicative senescence|downregulation of replicative senescence|down-regulation of replicative senescence							rph	2015-10-14T13:11:31Z					biological_process											owl:Class	
GO:1905103	biolink:NamedThing	integral component of lysosomal membrane	The component of the lysosome membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.	tmpzr1t_l9r_go_relaxed.owl	integral component of lysosome membrane|integral to lysosomal membrane							bf	2016-04-04T10:29:16Z					cellular_component											owl:Class	
GO:0046978	biolink:NamedThing	TAP1 binding	Binding to the TAP1 subunit of TAP (transporter associated with antigen processing) protein.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0046977	biolink:NamedThing	TAP binding	Binding to TAP protein, transporter associated with antigen processing protein. TAP protein is a heterodimeric peptide transporter consisting of the subunits TAP1 and TAP2.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0048538	biolink:NamedThing	thymus development	The process whose specific outcome is the progression of the thymus over time, from its formation to the mature structure. The thymus is a symmetric bi-lobed organ involved primarily in the differentiation of immature to mature T cells, with unique vascular, nervous, epithelial, and lymphoid cell components.	tmpzr1t_l9r_go_relaxed.owl						Note that this term is reserved for annotation of gene products involved in the formation of the thymus itself, not for gene products involved in T cell differentiation in the thymus or elsewhere.								biological_process											owl:Class	
GO:0031766	biolink:NamedThing	type 3 galanin receptor binding	Binding to a type 3 galanin receptor.	tmpzr1t_l9r_go_relaxed.owl	type 3 galanin receptor ligand													molecular_function											owl:Class	
GO:0031763	biolink:NamedThing	galanin receptor binding	Binding to a galanin receptor.	tmpzr1t_l9r_go_relaxed.owl	galanin receptor ligand													molecular_function											owl:Class	
GO:0110105	biolink:NamedThing	mRNA cleavage and polyadenylation specificity factor complex assembly	The aggregation, arrangement and bonding together of a set of components to form the mRNA cleavage and polyadenylation specificity factor complex.	tmpzr1t_l9r_go_relaxed.owl								kmv	2018-04-13T19:05:17Z					biological_process											owl:Class	
GO:0043601	biolink:NamedThing	nuclear replisome	A multi-component enzymatic machine at the nuclear replication fork, which mediates DNA replication. Includes DNA primase, one or more DNA polymerases, DNA helicases, and other proteins.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:1901083	biolink:NamedThing	pyrrolizidine alkaloid metabolic process	The chemical reactions and pathways involving pyrrolizidine alkaloid.	tmpzr1t_l9r_go_relaxed.owl	pyrrolizidine alkaloid metabolism							yaf	2012-07-05T10:27:56Z					biological_process											owl:Class	
GO:1905019	biolink:NamedThing	negative regulation of methionine-tRNA ligase activity	Any process that stops, prevents or reduces the frequency, rate or extent of methionine-tRNA ligase activity.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of methionine translase activity|inhibition of methionyl-transfer ribonucleic acid synthetase activity|downregulation of MetRS activity|down-regulation of methionine-tRNA ligase activity|down regulation of L-methionine:tRNAMet ligase (AMP-forming)|down-regulation of MetRS activity|negative regulation of methionyl-tRNA synthetase activity|negative regulation of methionyl-transfer RNA synthetase activity|down regulation of methionine-tRNA ligase activity|down regulation of methionyl-transfer ribonucleic acid synthetase activity|inhibition of MetRS activity|negative regulation of methionyl-transfer ribonucleate synthetase activity|downregulation of methionine-tRNA ligase activity|downregulation of methionyl-transfer ribonucleic acid synthetase activity|down-regulation of methionyl-transfer ribonucleic acid synthetase activity|negative regulation of methionyl-transfer ribonucleic acid synthetase activity|inhibition of methionyl-transfer ribonucleate synthetase activity|downregulation of methionyl-transfer ribonucleate synthetase activity|down regulation of methionine translase activity|inhibition of methionyl-transfer RNA synthetase activity|downregulation of L-methionine:tRNAMet ligase (AMP-forming)|inhibition of methionyl-tRNA synthetase activity|inhibition of methionine-tRNA ligase activity|down regulation of methionyl-tRNA synthetase activity|down-regulation of methionyl-transfer RNA synthetase activity|down-regulation of L-methionine:tRNAMet ligase (AMP-forming)|down regulation of methionyl-transfer RNA synthetase activity|downregulation of methionine translase activity|downregulation of methionyl-tRNA synthetase activity|negative regulation of methionine translase activity|down-regulation of methionyl-tRNA synthetase activity|negative regulation of L-methionine:tRNAMet ligase (AMP-forming)|inhibition of methionine translase activity|downregulation of methionyl-transfer RNA synthetase activity|inhibition of L-methionine:tRNAMet ligase (AMP-forming)|down-regulation of methionyl-transfer ribonucleate synthetase activity|negative regulation of MetRS activity|down regulation of MetRS activity|down regulation of methionyl-transfer ribonucleate synthetase activity							sl	2016-03-03T19:02:48Z					biological_process											owl:Class	
GO:1905018	biolink:NamedThing	regulation of methionine-tRNA ligase activity	Any process that modulates the frequency, rate or extent of methionine-tRNA ligase activity.	tmpzr1t_l9r_go_relaxed.owl	regulation of methionyl-transfer ribonucleate synthetase activity|regulation of L-methionine:tRNAMet ligase (AMP-forming)|regulation of methionyl-tRNA synthetase activity|regulation of methionyl-transfer RNA synthetase activity|regulation of methionyl-transfer ribonucleic acid synthetase activity|regulation of MetRS activity|regulation of methionine translase activity							sl	2016-03-03T19:02:39Z					biological_process											owl:Class	
GO:0047991	biolink:NamedThing	hydroxylamine oxidase activity	Catalysis of the reaction: hydroxylamine + O(2) = H(2)O + H(+) + nitrite.	tmpzr1t_l9r_go_relaxed.owl	hydroxylamine oxidoreductase|hydroxylamine:oxygen oxidoreductase activity|HAO				MetaCyc:HAONITRO-RXN|KEGG_REACTION:R00793|RHEA:19969|EC:1.7.3.6									molecular_function											owl:Class	
GO:0030517	biolink:NamedThing	negative regulation of axon extension	Any process that stops, prevents, or reduces the frequency, rate or extent of axon outgrowth.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of axon extension|down regulation of axon extension|downregulation of axon extension|inhibition of axon extension													biological_process											owl:Class	
GO:0043468	biolink:NamedThing	regulation of fucose catabolic process	Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of fucose.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0021522	biolink:NamedThing	spinal cord motor neuron differentiation	The process in which neuroepithelial cells in the ventral neural tube acquire specialized structural and/or functional features of motor neurons. Motor neurons innervate an effector (muscle or glandular) tissue and are responsible for transmission of motor impulses from the brain to the periphery. Differentiation includes the processes involved in commitment of a cell to a specific fate.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0021953	biolink:NamedThing	central nervous system neuron differentiation	The process in which a relatively unspecialized cell acquires specialized features of a neuron whose cell body resides in the central nervous system.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0097070	biolink:NamedThing	ductus arteriosus closure	The morphogenesis process in which the ductus arteriosus changes to no longer permit blood flow after birth. The ductus arteriosus is the shunt between the aorta and the pulmonary artery which allows blood to bypass the fetus' lungs.	tmpzr1t_l9r_go_relaxed.owl								pr	2011-06-15T04:00:46Z					biological_process											owl:Class	
GO:0071239	biolink:NamedThing	cellular response to streptomycin	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a streptomycin stimulus. Streptomycin is a commonly used antibiotic in cell culture media which acts only on prokaryotes and blocks transition from initiation complex to chain elongating ribosome.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-12-03T02:25:59Z					biological_process											owl:Class	
GO:0071236	biolink:NamedThing	cellular response to antibiotic	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antibiotic stimulus. An antibiotic is a chemical substance produced by a microorganism which has the capacity to inhibit the growth of or to kill other microorganisms.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-12-03T02:23:49Z					biological_process											owl:Class	
GO:0048080	biolink:NamedThing	negative regulation of cuticle pigmentation	Any process that stops, prevents, or reduces the frequency, rate or extent of establishment of a pattern of pigment in the cuticle of an organism.	tmpzr1t_l9r_go_relaxed.owl	downregulation of cuticle pigmentation|down-regulation of cuticle pigmentation|down regulation of cuticle pigmentation|inhibition of cuticle pigmentation													biological_process											owl:Class	
GO:0008153	biolink:NamedThing	para-aminobenzoic acid biosynthetic process	The chemical reactions and pathways resulting in the formation of para-aminobenzoic acid, an intermediate in the synthesis of folic acid, a compound which some organisms, e.g. prokaryotes, eukaryotic microbes, and plants, can synthesize de novo. Others, notably mammals, cannot. In yeast, it is present as a factor in the B complex of vitamins.	tmpzr1t_l9r_go_relaxed.owl	vitamin Bx biosynthesis|4-aminobenzoic acid biosynthesis|PABA biosynthetic process|p-aminobenzoic acid biosynthesis|PABA biosynthesis|para-aminobenzoic acid biosynthesis|para-aminobenzoic acid synthesis|vitamin Bx biosynthetic process|para-aminobenzoic acid formation|para-aminobenzoic acid anabolism|p-aminobenzoic acid biosynthetic process|4-aminobenzoic acid biosynthetic process													biological_process											owl:Class	
GO:2000056	biolink:NamedThing	regulation of Wnt signaling pathway involved in digestive tract morphogenesis	Any process that modulates the frequency, rate or extent of Wnt signaling pathway involved in digestive tract morphogenesis.	tmpzr1t_l9r_go_relaxed.owl	regulation of Wnt receptor signalling pathway involved in digestive tract morphogenesis|regulation of Wnt receptor signaling pathway involved in digestive tract morphogenesis|regulation of Wnt-activated signaling pathway involved in digestive tract morphogenesis							jl	2010-08-20T01:17:27Z					biological_process											owl:Class	
GO:0034598	biolink:NamedThing	phosphothreonine lyase activity	Catalysis of the removal of the phosphate group from phosphothreonine by cleavage of the C-OP bond with the concomitant abstraction of the alpha proton, generating a double bond-containing product.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0044501	biolink:NamedThing	modulation of signal transduction in other organism	The process in which an organism effects a change in a signal transduction process - a cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell - in a second organism.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-02-23T03:48:19Z					biological_process											owl:Class	
GO:1905676	biolink:NamedThing	positive regulation of adaptive immune memory response	Any process that activates or increases the frequency, rate or extent of adaptive immune memory response.	tmpzr1t_l9r_go_relaxed.owl	activation of adaptive immune memory response|upregulation of adaptive immune memory response|up-regulation of adaptive immune memory response|up regulation of adaptive immune memory response							tb	2016-11-11T22:24:49Z					biological_process											owl:Class	
GO:1905674	biolink:NamedThing	regulation of adaptive immune memory response	Any process that modulates the frequency, rate or extent of adaptive immune memory response.	tmpzr1t_l9r_go_relaxed.owl								tb	2016-11-11T22:24:33Z					biological_process											owl:Class	
GO:0019896	biolink:NamedThing	axonal transport of mitochondrion	The directed movement of mitochondria along microtubules in nerve cell axons.	tmpzr1t_l9r_go_relaxed.owl	axon transport of mitochondria													biological_process											owl:Class	
GO:0061007	biolink:NamedThing	hepaticobiliary system process	An system process carried out by any of the organs or tissues of the hepaticobiliary system. The hepaticobiliary system is responsible for metabolic and catabolic processing of small molecules absorbed from the blood or gut, hormones and serum proteins, detoxification, storage of glycogen, triglycerides, metals and lipid soluble vitamins and excretion of bile. Included are the synthesis of albumin, blood coagulation factors, complement, and specific binding proteins.	tmpzr1t_l9r_go_relaxed.owl	hepatobiliary system process							dph	2010-01-22T09:09:10Z					biological_process											owl:Class	
GO:0060381	biolink:NamedThing	positive regulation of single-stranded telomeric DNA binding	Any process that increases the frequency, rate or extent of single-stranded telomeric DNA binding.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of telomeric ssDNA binding													biological_process											owl:Class	
GO:1904744	biolink:NamedThing	positive regulation of telomeric DNA binding	Any process that activates or increases the frequency, rate or extent of telomeric DNA binding.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of telomeric repeat binding|activation of telomere binding|positive regulation of telomere binding|positive regulation of telomeric repeat binding|activation of telomeric repeat binding|upregulation of telomere binding|up-regulation of telomere binding|up regulation of telomeric repeat binding|upregulation of telomeric DNA binding|up regulation of telomere binding|up regulation of telomeric DNA binding|upregulation of telomeric repeat binding|activation of telomeric DNA binding|up-regulation of telomeric DNA binding							nc	2015-10-19T12:19:01Z					biological_process											owl:Class	
GO:0106013	biolink:NamedThing	negative regulation of protein localization to cell cortex of cell tip	Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to the cell cortex of the cell tip.	tmpzr1t_l9r_go_relaxed.owl								hjd	2017-04-28T13:45:38Z					biological_process											owl:Class	
GO:1990895	biolink:NamedThing	regulation of protein localization to cell cortex of cell tip	Any process that modulates the frequency, rate or extent of protein localization to cell cortex of cell tip.	tmpzr1t_l9r_go_relaxed.owl								vw	2015-11-04T21:53:15Z					biological_process											owl:Class	
GO:2000029	biolink:NamedThing	regulation of proanthocyanidin biosynthetic process	Any process that modulates the frequency, rate or extent of proanthocyanidin biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of proanthocyanidin anabolism|regulation of proanthocyanidin synthesis|regulation of proanthocyanidin biosynthesis|regulation of proanthocyanidin formation							tb	2010-08-05T11:28:08Z					biological_process											owl:Class	
GO:0055023	biolink:NamedThing	positive regulation of cardiac muscle tissue growth	Any process that activates, maintains or increases the frequency, rate or extent of cardiac muscle growth.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of heart muscle growth|activation of cardiac muscle growth|up-regulation of cardiac muscle growth|up regulation of cardiac muscle growth|upregulation of cardiac muscle growth|stimulation of cardiac muscle growth													biological_process											owl:Class	
GO:0000949	biolink:NamedThing	aromatic amino acid family catabolic process to alcohol via Ehrlich pathway	The chemical reactions and pathways involving the catabolism of aromatic amino acids to produce aromatic alcohols with one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. When an aromatic family amino acid, phenylalanine, tyrosine, or tryptophan, is used as the substrate, 2-phenylethanol, 4-hydroxyphenylethanol, or tryptophol, respectively, is produced. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of alcohols, often collectively referred to as fusel alcohols. Depending on the redox state of the cells, carboxylic acid derivatives may be produced instead of alcohols.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0032305	biolink:NamedThing	positive regulation of icosanoid secretion	Any process that activates or increases the frequency, rate or extent of the controlled release of an icosanoid from a cell.	tmpzr1t_l9r_go_relaxed.owl	stimulation of icosanoid secretion|up regulation of icosanoid secretion|activation of icosanoid secretion|up-regulation of icosanoid secretion|positive regulation of eicosanoid secretion|upregulation of icosanoid secretion													biological_process											owl:Class	
GO:0102322	biolink:NamedThing	2-propylphenol monooxygenase activity	Catalysis of the reaction: 2-propylphenol + O2 + NADH + H+ = 3-propylcatechol + H2O + NAD.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-13151									molecular_function											owl:Class	
GO:0034102	biolink:NamedThing	erythrocyte clearance	The selective elimination of erythrocytes from the body by autoregulatory mechanisms.	tmpzr1t_l9r_go_relaxed.owl	red blood cell clearance|RBC clearance|neocytolysis					Note that this term is intended for annotation of self-gene products that lead to elimination of erythrocytes without the involvement of a symbiont.								biological_process											owl:Class	
GO:0016361	biolink:NamedThing	activin receptor activity, type I	Combining with activin-bound type II activin receptor to initiate a change in cell activity; upon binding, acts as a downstream transducer of activin signals.	tmpzr1t_l9r_go_relaxed.owl	type I activin receptor activity													molecular_function											owl:Class	
GO:0017002	biolink:NamedThing	activin-activated receptor activity	Combining with activin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. Activin is one of two gonadal glycoproteins related to transforming growth factor beta.	tmpzr1t_l9r_go_relaxed.owl	activin receptor activity					Note that this term represents an activity and not a gene product, and should only be used when the receptor binds the ligand activin. For binding to other extracellular ligands, consider annotating to terms under 'transmembrane signaling receptor activity ; GO:0004888.								molecular_function											owl:Class	
GO:0009986	biolink:NamedThing	cell surface	The external part of the cell wall and/or plasma membrane.	tmpzr1t_l9r_go_relaxed.owl	cell associated|cell bound					Note that this term is intended to annotate gene products that are attached (integrated or loosely bound) to the plasma membrane or cell wall.						GO:0009928|GO:0009929		cellular_component											owl:Class	
GO:0031633	biolink:NamedThing	xanthophore	A chromatophore containing yellow pigment.	tmpzr1t_l9r_go_relaxed.owl						Note that this term refers to a subcellular structure, and should not be confused with the specialized cells known as xanthophores, which produce yellow pigment and are found in fish and amphibian skin. Note that several terms in the biological process ontology ('xanthophore differentiation ; GO:0050936' and its children) refer to xanthophores in the sense of pigment-producing cells.								cellular_component											owl:Class	
GO:0051756	biolink:NamedThing	meiotic sister chromatid centromere separation	The cell cycle process in which the centromeres of sister chromatids are physically detached from each other during meiosis.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0046171	biolink:NamedThing	octanol biosynthetic process	The chemical reactions and pathways resulting in the formation of octanol, the 8-carbon alcohol with the formula C8H17OH.	tmpzr1t_l9r_go_relaxed.owl	octanol anabolism|octanol formation|octanol biosynthesis|octanol synthesis													biological_process											owl:Class	
GO:0002724	biolink:NamedThing	regulation of T cell cytokine production	Any process that modulates the frequency, rate, or extent of T cell cytokine production.	tmpzr1t_l9r_go_relaxed.owl	regulation of T lymphocyte cytokine production|regulation of T-cell cytokine production|regulation of T-lymphocyte cytokine production													biological_process											owl:Class	
GO:0047720	biolink:NamedThing	indoleacetaldoxime dehydratase activity	Catalysis of the reaction: (indol-3-yl)acetaldehyde oxime = (indol-3-yl)acetonitrile + H(2)O.	tmpzr1t_l9r_go_relaxed.owl	3-indoleacetaldoxime hydro-lyase activity|(indol-3-yl)acetaldehyde-oxime hydro-lyase [(indol-3-yl)acetonitrile-forming]|indoleacetaldoxime hydro-lyase activity|indole-3-acetaldehyde-oxime hydro-lyase activity|indole-3-acetaldoxime hydro-lyase activity|(indol-3-yl)acetaldehyde-oxime hydro-lyase activity				KEGG_REACTION:R04093|RHEA:23156|EC:4.99.1.6|MetaCyc:RXN-1403									molecular_function											owl:Class	
GO:0071958	biolink:NamedThing	new mitotic spindle pole body	The spindle pole body that is formed by spindle pole body duplication, and to which proteins involved in mitotic exit signaling (for example, the septation initiation network in fission yeast) localize.	tmpzr1t_l9r_go_relaxed.owl	new SPB							mah	2011-06-01T02:34:34Z					cellular_component											owl:Class	
GO:0044732	biolink:NamedThing	mitotic spindle pole body	The microtubule organizing center that forms as part of the mitotic cell cycle; functionally homologous to the animal cell centrosome.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-11-06T15:44:02Z					cellular_component											owl:Class	
GO:0002751	biolink:NamedThing	antigen processing and presentation following receptor mediated endocytosis	Antigen processing and presentation which is initiated by uptake of antigen receptor-mediated endocytosis.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0002745	biolink:NamedThing	antigen processing and presentation initiated by receptor mediated uptake of antigen	Antigen processing and presentation which is initiated by uptake of antigen bound to a cell surface receptor.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0046037	biolink:NamedThing	GMP metabolic process	The chemical reactions and pathways involving GMP, guanosine monophosphate.	tmpzr1t_l9r_go_relaxed.owl	GMP metabolism													biological_process											owl:Class	
GO:0031205	biolink:NamedThing	endoplasmic reticulum Sec complex	An endoplasmic reticulum membrane-associated complex involved in the translocation of proteins that are targeted to the ER. In yeast, this complex consists of two subcomplexes, namely, the Sec61 complex and the Sec62/Sec63 complex.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:2000004	biolink:NamedThing	regulation of metanephric S-shaped body morphogenesis	Any process that modulates the frequency, rate or extent of metanephric S-shaped body morphogenesis.	tmpzr1t_l9r_go_relaxed.owl								jl	2010-07-30T02:14:33Z					biological_process											owl:Class	
GO:1900746	biolink:NamedThing	regulation of vascular endothelial growth factor signaling pathway	Any process that modulates the frequency, rate or extent of vascular endothelial growth factor signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	regulation of VEGF signaling|regulation of vascular endothelial growth factor signalling pathway|regulation of VEGF-activated signaling pathway							pm	2012-05-29T08:28:06Z					biological_process											owl:Class	
GO:1905884	biolink:NamedThing	negative regulation of triglyceride transport	Any process that stops, prevents or reduces the frequency, rate or extent of triglyceride transport.	tmpzr1t_l9r_go_relaxed.owl	downregulation of triglyceride transport|down regulation of triacylglycerol transport|down-regulation of triglyceride transport|inhibition of triacylglycerol transport|down regulation of triglyceride transport|negative regulation of triacylglycerol transport|inhibition of triglyceride transport|downregulation of triacylglycerol transport|down-regulation of triacylglycerol transport							rz	2017-01-31T11:32:39Z					biological_process											owl:Class	
GO:1905883	biolink:NamedThing	regulation of triglyceride transport	Any process that modulates the frequency, rate or extent of triglyceride transport.	tmpzr1t_l9r_go_relaxed.owl	regulation of triacylglycerol transport							rz	2017-01-31T11:32:29Z					biological_process											owl:Class	
GO:0030590	biolink:NamedThing	first cell cycle pseudocleavage	A process that occurs during the first cell cycle in an embryo, in which anterior cortical contractions culminate in a single partial constriction of the embryo called the pseudocleavage furrow. An example of this process is found in nematode worms.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0030588	biolink:NamedThing	pseudocleavage	Partial constriction of the cytoplasm of a cell to form a furrow that resembles a cleavage furrow but does not complete cytokinesis.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0060094	biolink:NamedThing	positive regulation of synaptic transmission, glycinergic	Any process that activates or increases the frequency, rate or extent of glycinergic synaptic transmission. Glycinergic synaptic transmission is the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glycine.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of glycinergic synaptic transmission													biological_process											owl:Class	
GO:0060092	biolink:NamedThing	regulation of synaptic transmission, glycinergic	Any process that modulates the frequency, rate or extent of glycinergic synaptic transmission. Glycinergic synaptic transmission is the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glycine.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0016362	biolink:NamedThing	activin receptor activity, type II	Combining with activin to initiate a change in cell activity; upon ligand binding, binds to and catalyses the phosphorylation of a type I activin receptor.	tmpzr1t_l9r_go_relaxed.owl	type II activin receptor activity				Reactome:R-HSA-201443									molecular_function											owl:Class	
GO:0008311	biolink:NamedThing	double-stranded DNA 3'-5' exodeoxyribonuclease activity	Catalysis of the sequential cleavage of mononucleotides from a free 3' terminus of a double-stranded DNA molecule.	tmpzr1t_l9r_go_relaxed.owl	double-stranded DNA specific 3'-5' exodeoxyribonuclease activity													molecular_function											owl:Class	
GO:1901973	biolink:NamedThing	proline binding	Binding to proline.	tmpzr1t_l9r_go_relaxed.owl								pm	2013-02-26T14:58:01Z					molecular_function											owl:Class	
GO:0110147	biolink:NamedThing	protein maturation by nickel ion transfer	A process that contributes to the delivery of nickel ions to a target protein to facilitate its maturation.	tmpzr1t_l9r_go_relaxed.owl								kmv	2019-05-31T14:41:20Z					biological_process											owl:Class	
GO:0035635	biolink:NamedThing	entry of bacterium into host cell	The process in which a bacterium enters a host cell. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	bacterial entry into host cell|invasion of bacteria into host cell							bf	2011-01-13T02:26:54Z					biological_process											owl:Class	
GO:0072056	biolink:NamedThing	pyramid development	The process whose specific outcome is the progression of the kidney pyramids over time, from its formation to the mature structure. Kidney pyramids are the conical masses that constitute the renal medulla in a multi-lobed mammalian kidney; they contain the loops of Henle and the medullary collecting ducts.	tmpzr1t_l9r_go_relaxed.owl	renal pyramid development|pyramids development|kidney pyramid development|renal medulla development							mah	2010-01-25T04:01:36Z					biological_process											owl:Class	
GO:0002272	biolink:NamedThing	plasmacytoid dendritic cell differentiation involved in immune response	The process in which an immature plasmacytoid dendritic cell acquires the specialized features of a mature plasmacytoid dendritic cell contributing to an immune response.	tmpzr1t_l9r_go_relaxed.owl	plasmacytoid dendritic cell differentiation during immune response													biological_process											owl:Class	
GO:0055039	biolink:NamedThing	trichocyst	A crystalline exocytotic organelle composed of small, acidic proteins existing primarily as disulphide-linked dimers. The trichocyst is an organelle that releases long filamentous proteins that capture predators in net-like structures, to slow them down when the cell is disturbed. The protein is nontoxic and shaped like a long, striated, fibrous shaft.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Trichocyst									cellular_component											owl:Class	
GO:0043264	biolink:NamedThing	extracellular non-membrane-bounded organelle	Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane and occurring outside the cell.	tmpzr1t_l9r_go_relaxed.owl	extracellular non-membrane-enclosed organelle													cellular_component											owl:Class	
GO:0001616	biolink:NamedThing	growth hormone secretagogue receptor activity	Combining with ghrelin to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	ghrelin receptor activity													molecular_function											owl:Class	
GO:0071482	biolink:NamedThing	cellular response to light stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light stimulus, electromagnetic radiation of wavelengths classified as infrared, visible or ultraviolet light.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-12-18T02:03:49Z					biological_process											owl:Class	
GO:0048264	biolink:NamedThing	determination of ventral identity	The regionalization process that results in the determination of the identity of part of an organism or organ where those parts are of the type that occur in the ventral region. Identity is considered to be the aggregate of characteristics by which a structure is recognized.	tmpzr1t_l9r_go_relaxed.owl	determination of abaxial identity													biological_process											owl:Class	
GO:0009953	biolink:NamedThing	dorsal/ventral pattern formation	The regionalization process in which the areas along the dorsal/ventral axis are established that will lead to differences in cell differentiation. The dorsal/ventral axis is defined by a line that runs orthogonal to both the anterior/posterior and left/right axes. The dorsal end is defined by the upper or back side of an organism. The ventral end is defined by the lower or front side of an organism.	tmpzr1t_l9r_go_relaxed.owl	dorsal/ventral pattern specification|dorsoventral pattern formation|dorsal-ventral pattern formation													biological_process											owl:Class	
GO:0047371	biolink:NamedThing	butyrate-acetoacetate CoA-transferase activity	Catalysis of the reaction: acetoacetate + butanoyl-CoA = acetoacetyl-CoA + butanoate.	tmpzr1t_l9r_go_relaxed.owl	butyryl-CoA-acetoacetate CoA-transferase activity|butyryl coenzyme A-acetoacetate coenzyme A-transferase activity|butanoyl-CoA:acetoacetate CoA-transferase activity				KEGG_REACTION:R01365|EC:2.8.3.9|MetaCyc:2.8.3.9-RXN|RHEA:12961									molecular_function											owl:Class	
GO:1904252	biolink:NamedThing	negative regulation of bile acid metabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of bile acid metabolic process.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of bile acid metabolism|inhibition of bile acid metabolism|down regulation of bile acid metabolism|downregulation of bile acid metabolic process|down-regulation of bile acid metabolic process|downregulation of bile acid metabolism|down regulation of bile acid metabolic process|down-regulation of bile acid metabolism|inhibition of bile acid metabolic process							bf	2015-05-20T11:04:35Z					biological_process											owl:Class	
GO:0009677	biolink:NamedThing	double fertilization forming two zygotes	Rudimentary double fertilization where one of the two sperm nuclei from the pollen tube fuses with the egg nucleus to form a 2n zygote, and the other fuses with the ventral canal cell nucleus to form a second zygote, which soon degenerates. An example of this process is found in the Gnetophytes, such as Welwitschia mirabilis.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0009566	biolink:NamedThing	fertilization	The union of gametes of opposite sexes during the process of sexual reproduction to form a zygote. It involves the fusion of the gametic nuclei (karyogamy) and cytoplasm (plasmogamy).	tmpzr1t_l9r_go_relaxed.owl	syngamy	https://github.com/geneontology/go-ontology/issues/20176			Wikipedia:Fertilisation									biological_process											owl:Class	
GO:0035623	biolink:NamedThing	renal glucose absorption	A renal system process in which glucose is taken up from the collecting ducts and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures.	tmpzr1t_l9r_go_relaxed.owl	nephron glucose absorption|glucose reabsorption							bf	2010-12-08T04:14:23Z					biological_process											owl:Class	
GO:1902069	biolink:NamedThing	negative regulation of sphingolipid mediated signaling pathway	Any process that stops, prevents or reduces the frequency, rate or extent of sphingolipid signaling.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of sphingolipid signaling pathway|down-regulation of sphingolipid signaling pathway|down regulation of sphingolipid mediated signaling pathway|down regulation of sphingolipid signaling pathway|downregulation of sphingolipid signaling pathway|down-regulation of sphingolipid mediated signaling pathway|downregulation of sphingolipid mediated signaling pathway|inhibition of sphingolipid mediated signaling pathway|inhibition of sphingolipid signaling pathway							bf	2013-04-18T13:24:51Z					biological_process											owl:Class	
GO:1903006	biolink:NamedThing	positive regulation of protein K63-linked deubiquitination	Any process that activates or increases the frequency, rate or extent of protein K63-linked deubiquitination.	tmpzr1t_l9r_go_relaxed.owl	activation of protein K63-linked deubiquitination|up-regulation of protein K63-linked deubiquitination|upregulation of protein K63-linked deubiquitination|up regulation of protein K63-linked deubiquitination							bf	2014-05-12T15:40:55Z					biological_process											owl:Class	
GO:1903004	biolink:NamedThing	regulation of protein K63-linked deubiquitination	Any process that modulates the frequency, rate or extent of protein K63-linked deubiquitination.	tmpzr1t_l9r_go_relaxed.owl								bf	2014-05-12T15:40:43Z					biological_process											owl:Class	
GO:0102292	biolink:NamedThing	30-hydroxy-beta-amyrin 11-hydroxylase activity	Catalysis of the reaction: 30-hydroxy-beta-amyrin + O2 + NADPH + H+ <=> 11alpha,30-dihydroxy-beta-amyrin + H2O + NADP.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-12683									molecular_function											owl:Class	
GO:0009909	biolink:NamedThing	regulation of flower development	Any process that modulates the frequency, rate or extent of flower development.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0033441	biolink:NamedThing	AAU codon-amino acid adaptor activity	A triplet codon-amino acid adaptor activity that recognizes an AAU codon.	tmpzr1t_l9r_go_relaxed.owl	AAT codon-amino acid adaptor activity|asparagine tRNA					Note that in the standard genetic code, AAT codes for asparagine.								molecular_function											owl:Class	
GO:0038148	biolink:NamedThing	chemokine (C-C motif) ligand 2 signaling pathway	A series of molecular signals initiated by the binding of the C-C chemokine CCL2 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.	tmpzr1t_l9r_go_relaxed.owl	CCL2 signaling pathway							bf	2012-05-11T11:36:08Z					biological_process											owl:Class	
GO:0106356	biolink:NamedThing	4-hydroxybenzoate 3-monooxygenase [NADPH] activity	Catalysis of the reaction: 4-hydroxybenzoate + H+ + NADPH + O2 = 3,4-dihydroxybenzoate + H2O + NADP+.	tmpzr1t_l9r_go_relaxed.owl					RHEA:19477			hjd	2021-02-02T05:51:57Z					molecular_function											owl:Class	
GO:0018671	biolink:NamedThing	4-hydroxybenzoate 3-monooxygenase [NAD(P)H] activity	Catalysis of the reaction: 4-hydroxybenzoate + NAD(P)H + H+ + O2 = 3,4-dihydroxybenzoate + NAD(P)+ + H2O.	tmpzr1t_l9r_go_relaxed.owl	4-hydroxybenzoate 3-hydroxylase activity|4-hydroxybenzoate 3-monooxygenase (reduced nicotinamide adenine dinucleotide (phosphate))|4-hydroxybenzoate-3-hydroxylase activity|4-hydroxybenzoate,NAD(P)H:oxygen oxidoreductase (3-hydroxylating)				MetaCyc:1.14.13.33-RXN|EC:1.14.13.33									molecular_function											owl:Class	
GO:1904006	biolink:NamedThing	negative regulation of phospholipase D activity	Any process that stops, prevents or reduces the frequency, rate or extent of phospholipase D activity.	tmpzr1t_l9r_go_relaxed.owl	inhibition of choline phosphatase activity|down regulation of lipophosphodiesterase II activity|down-regulation of phosphatidylcholine phosphatidohydrolase activity|inhibition of lecithinase D activity|negative regulation of choline phosphatase activity|down regulation of phosphatidylcholine phosphatidohydrolase activity|downregulation of lipophosphodiesterase II activity|downregulation of phospholipase D activity|down regulation of lecithinase D activity|down-regulation of lecithinase D activity|inhibition of phosphatidylcholine phosphatidohydrolase activity|down-regulation of phospholipase D activity|inhibition of phospholipase D activity|down regulation of choline phosphatase activity|inhibition of lipophosphodiesterase II activity|down regulation of phospholipase D activity|down-regulation of choline phosphatase activity|negative regulation of lecithinase D activity|downregulation of lecithinase D activity|downregulation of choline phosphatase activity|down-regulation of lipophosphodiesterase II activity|negative regulation of phosphatidylcholine phosphatidohydrolase activity|negative regulation of lipophosphodiesterase II activity|downregulation of phosphatidylcholine phosphatidohydrolase activity							sl	2015-03-06T17:20:11Z					biological_process											owl:Class	
GO:0002180	biolink:NamedThing	5-lipoxygenase complex	An nuclear membrane protein complex having arachidonate 5-lipoxygenase activity.	tmpzr1t_l9r_go_relaxed.owl								hjd	2011-06-09T01:05:53Z					cellular_component											owl:Class	
GO:0055130	biolink:NamedThing	D-alanine catabolic process	The chemical reactions and pathways resulting in the breakdown of D-alanine, the D-enantiomer of the amino acid alanine.	tmpzr1t_l9r_go_relaxed.owl	(2R)-2-aminopropanoic acid catabolic process							jid	2009-10-22T02:02:42Z					biological_process											owl:Class	
GO:0034041	biolink:NamedThing	ABC-type sterol transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + sterol(in) = ADP + phosphate + sterol(out).	tmpzr1t_l9r_go_relaxed.owl	sterol-transporting ATPase activity|ATPase-coupled sterol transmembrane transporter activity|ATP-coupled sterol transmembrane transporter activity|ATP-dependent sterol transmembrane transporter activity													molecular_function											owl:Class	
GO:0033579	biolink:NamedThing	protein galactosylation in endoplasmic reticulum	The addition of a galactose unit to a protein amino acid in the endoplasmic reticulum.	tmpzr1t_l9r_go_relaxed.owl	protein amino acid galactosylation in endoplasmic reticulum|protein amino acid galactosylation in ER													biological_process											owl:Class	
GO:0102834	biolink:NamedThing	1-18:1-2-16:0-monogalactosyldiacylglycerol acyl-lipid omega-6 desaturase activity	Catalysis of the reaction: 1-18:1-2-16:0-monogalactosyldiacylglycerol + O2 + a reduced electron acceptor <=> 1-18:2-2-16:0-monogalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-8294|EC:1.14.19.23									molecular_function											owl:Class	
GO:0071266	biolink:NamedThing	'de novo' L-methionine biosynthetic process	The chemical reactions and pathways resulting in the formation of L-methionine, the L-enantiomer of (2S)-2-amino-4-(methylsulfanyl)butanoic acid, from simpler components.	tmpzr1t_l9r_go_relaxed.owl	'de novo' L-methionine anabolism|'de novo' L-methionine formation|'de novo' L-methionine biosynthesis|'de novo' L-methionine synthesis							mah	2009-12-09T04:34:41Z					biological_process											owl:Class	
GO:1903720	biolink:NamedThing	negative regulation of I-kappaB phosphorylation	Any process that stops, prevents or reduces the frequency, rate or extent of I-kappaB phosphorylation.	tmpzr1t_l9r_go_relaxed.owl	inhibition of inhibitor of kappaB phosphorylation|down-regulation of I-kappaB phosphorylation|downregulation of inhibitor of kappaB phosphorylation|down regulation of IKB phosphorylation|negative regulation of inhibitor of kappaB phosphorylation|negative regulation of inhibitor of NF-kappaB phosphorylation|down-regulation of IkappaB phosphorylation|downregulation of inhibitor of NF-kappaB phosphorylation|negative regulation of IkappaB phosphorylation|inhibition of I-kappaB phosphorylation|down regulation of inhibitor of NF-kappaB phosphorylation|down regulation of inhibitor of kappaB phosphorylation|downregulation of IkappaB phosphorylation|down regulation of I-kappaB phosphorylation|inhibition of IkappaB phosphorylation|down-regulation of inhibitor of NF-kappaB phosphorylation|down-regulation of IKB phosphorylation|down regulation of IkappaB phosphorylation|down-regulation of inhibitor of kappaB phosphorylation|inhibition of inhibitor of NF-kappaB phosphorylation|downregulation of IKB phosphorylation|downregulation of I-kappaB phosphorylation|negative regulation of IKB phosphorylation|inhibition of IKB phosphorylation							lb	2014-12-08T15:45:16Z					biological_process											owl:Class	
GO:0150056	biolink:NamedThing	amylin receptor complex 1	A G protein-coupled receptor complex that serves as a receptor for amylin polypeptide (AMY) and consists of a calcitonin receptor (CTR/CALCR) and a receptor activity-modifying protein (RAMP) 1. Amylin receptor complex 1 (AMY1) also serves as a receptor for the calcitonin related peptide (CGRP) and adrenomedullin (AM/ADM).	tmpzr1t_l9r_go_relaxed.owl	AMY1 complex							bc	2018-06-21T10:47:10Z					cellular_component											owl:Class	
GO:0030296	biolink:NamedThing	protein tyrosine kinase activator activity	Increases the activity of a protein tyrosine kinase, an enzyme which phosphorylates a tyrosyl phenolic group on a protein.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0035544	biolink:NamedThing	negative regulation of SNARE complex assembly	Any process that decreases the frequency, rate or extent of assembly of the SNARE complex. The SNARE complex is a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers.	tmpzr1t_l9r_go_relaxed.owl								bf	2010-05-10T01:51:10Z					biological_process											owl:Class	
GO:0035542	biolink:NamedThing	regulation of SNARE complex assembly	Any process that modulates the frequency, rate or extent of assembly of the SNARE complex. The SNARE complex is a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers.	tmpzr1t_l9r_go_relaxed.owl								bf	2010-05-10T01:49:35Z					biological_process											owl:Class	
GO:0042034	biolink:NamedThing	peptidyl-L-lysine methyl ester biosynthetic process from peptidyl-lysine	The modification of a C-terminal peptidyl-lysine to form peptidyl-L-lysine methyl ester.	tmpzr1t_l9r_go_relaxed.owl	peptidyl-lysine esterification				RESID:AA0318									biological_process											owl:Class	
GO:0097716	biolink:NamedThing	copper ion transport across blood-brain barrier	The directed movement of copper (Cu) ions passing through the blood-brain barrier.	tmpzr1t_l9r_go_relaxed.owl	copper ion transport across BBB							pr	2016-08-23T14:35:54Z					biological_process											owl:Class	
GO:0150104	biolink:NamedThing	transport across blood-brain barrier	The directed movement of substances (e.g. macromolecules, small molecules, ions) through the blood-brain barrier.	tmpzr1t_l9r_go_relaxed.owl	transport across blood brain barrier|transport across BBB							bc	2019-05-27T09:12:03Z					biological_process											owl:Class	
GO:0031335	biolink:NamedThing	regulation of sulfur amino acid metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving sulfur amino acids.	tmpzr1t_l9r_go_relaxed.owl	regulation of sulfur amino acid metabolism													biological_process											owl:Class	
GO:1900581	biolink:NamedThing	(17Z)-protosta-17(20),24-dien-3beta-ol biosynthetic process	The chemical reactions and pathways resulting in the formation of (17Z)-protosta-17(20),24-dien-3beta-ol.	tmpzr1t_l9r_go_relaxed.owl	(17Z)-protosta-17(20),24-dien-3beta-ol formation|(17Z)-protosta-17(20),24-dien-3beta-ol biosynthesis|(17Z)-protosta-17(20),24-dien-3beta-ol anabolism|(17Z)-protosta-17(20),24-dien-3beta-ol synthesis							di	2012-05-15T06:47:38Z					biological_process											owl:Class	
GO:0010686	biolink:NamedThing	tetracyclic triterpenoid biosynthetic process	The chemical reactions and pathways resulting in the formation of tetracyclic triterpenoid compounds, terpenoids with six isoprene units and 4 carbon rings.	tmpzr1t_l9r_go_relaxed.owl	tetracyclic triterpenoid biosynthesis													biological_process											owl:Class	
GO:0003095	biolink:NamedThing	pressure natriuresis	The process in which the volume of blood increases renal pressure and thereby results in both an increase in urine volume (diuresis) and an increase in the amount of sodium excreted in the urine (natriuresis).	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0043137	biolink:NamedThing	DNA replication, removal of RNA primer	Removal of the Okazaki RNA primer from the lagging strand of replicating DNA, by a combination of the actions of DNA polymerase, DNA helicase and an endonuclease.	tmpzr1t_l9r_go_relaxed.owl	Okazaki initiator RNA removal													biological_process											owl:Class	
GO:0070596	biolink:NamedThing	(1->3)-alpha-glucan biosynthetic process	The chemical reactions and pathways resulting in the formation of (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds.	tmpzr1t_l9r_go_relaxed.owl	alpha-1,3 glucan anabolism|alpha-1,3 glucan biosynthesis|1,3-alpha-glucan synthesis|alpha-1,3 glucan synthesis|alpha-1,3 glucan biosynthetic process|1,3-alpha-glucan biosynthesis|1,3-alpha-glucan anabolism|alpha-1,3 glucan formation|1,3-alpha-glucan biosynthetic process|1,3-alpha-glucan formation							mah	2009-04-28T03:39:24Z					biological_process											owl:Class	
GO:0042926	biolink:NamedThing	3-hydroxyphenylpropionic acid transmembrane transporter activity	Enables the directed movement of 3-hydroxyphenylpropionic acid from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	3-hydroxyphenylpropionic acid transporter activity|m-hydroxyphenylpropionic acid transporter activity|3-(3-hydroxyphenyl)propionic acid transporter activity													molecular_function											owl:Class	
GO:1901766	biolink:NamedThing	phosphinothricin biosynthetic process	The chemical reactions and pathways resulting in the formation of phosphinothricin.	tmpzr1t_l9r_go_relaxed.owl	phosphinothricin formation|phosphinothricin synthesis|phosphinothricin anabolism|phosphinothricin biosynthesis							yaf	2013-01-15T10:02:46Z					biological_process											owl:Class	
GO:0006053	biolink:NamedThing	N-acetylmannosamine catabolic process	The chemical reactions and pathways resulting in the breakdown of N-acetylmannosamine, the acetylated derivative of mannosamine, 2-amino-2-deoxymannose.	tmpzr1t_l9r_go_relaxed.owl	N-acetylmannosamine catabolism|N-acetylmannosamine degradation|N-acetylmannosamine breakdown													biological_process											owl:Class	
GO:0006051	biolink:NamedThing	N-acetylmannosamine metabolic process	The chemical reactions and pathways involving N-acetylmannosamine, the acetylated derivative of mannosamine, 2-amino-2-deoxymannose.	tmpzr1t_l9r_go_relaxed.owl	N-acetylmannosamine metabolism													biological_process											owl:Class	
GO:0086058	biolink:NamedThing	voltage-gated calcium channel activity involved in Purkinje myocyte cell action potential	Enables the transmembrane transfer of a calcium ion by a voltage-gated channel across the plasma membrane of an Purkinje myocyte cell that contributes to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.	tmpzr1t_l9r_go_relaxed.owl								dph	2011-11-17T12:35:02Z					molecular_function											owl:Class	
GO:0035614	biolink:NamedThing	snRNA stem-loop binding	Binding to a stem-loop in a small nuclear RNA (snRNA). An RNA stem-loop is a secondary RNA structure consisting of a double-stranded RNA (dsRNA) stem and a terminal loop.	tmpzr1t_l9r_go_relaxed.owl	snRNA hairpin loop binding|small nuclear RNA stem-loop binding|snRNA hairpin binding							bf	2010-11-26T10:43:17Z					molecular_function											owl:Class	
GO:1990046	biolink:NamedThing	stress-induced mitochondrial fusion	Merging of two or more mitochondria within a cell to form a single compartment, as a result of a disturbance in cellular homeostasis.	tmpzr1t_l9r_go_relaxed.owl	SIMH|stress-induced mitochondrial hyperfusion|mitochondrial fusion in response to stress							pr	2013-02-15T16:01:55Z					biological_process											owl:Class	
GO:0048911	biolink:NamedThing	efferent axon development in anterior lateral line nerve	The process whose specific outcome is the progression of an efferent axon in the anterior lateral line nerve over time from its formation to the mature structure. This process includes axonogenesis and pathfinding of the efferent axons in the anterior lateral line nerve.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0048894	biolink:NamedThing	efferent axon development in a lateral line nerve	The process whose specific outcome is the progression of an efferent axon in a lateral line nerve over time from its formation to the mature structure. This process includes axonogenesis and pathfinding of the efferent axons in any lateral line nerve.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0070625	biolink:NamedThing	zymogen granule exocytosis	The release of intracellular molecules contained within the zymogen granule by fusion of the granule with the plasma membrane of the oocyte, requiring calcium ions.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-05-01T03:56:02Z					biological_process											owl:Class	
GO:0018170	biolink:NamedThing	C-terminal peptidyl-polyglutamic acid amidation	The formation of a C-terminal peptidyl-polyglutamic acid to form a peptidyl-N-L-glutamyl-poly-L-glutamic acid C-terminus.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0261									biological_process											owl:Class	
GO:0018040	biolink:NamedThing	C-terminal peptidyl-glutamic acid amidation	The formation of a C-terminal peptidyl-glutamic acid amide by hydrolysis and oxidation of an interior Glu-Gly peptide in a secreted protein.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0087									biological_process											owl:Class	
GO:0035046	biolink:NamedThing	pronuclear migration	The directed movement of the male and female pronuclei towards each other prior to their fusion.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0047654	biolink:NamedThing	alliin lyase activity	Catalysis of the reaction: an S-alkyl-L-cysteine S-oxide = an alkyl sulfenate + 2-aminoacrylate.	tmpzr1t_l9r_go_relaxed.owl	L-cysteine sulfoxide lyase activity|cysteine sulfoxide lyase activity|alliin alkyl-sulfenate-lyase activity|cysteine sulphoxide lyase activity|alliinase activity|alkylcysteine sulfoxide lyase activity|S-alkyl-L-cysteine S-oxide alkyl-sulfenate-lyase (2-aminoacrylate-forming)|S-alkylcysteine sulfoxide lyase activity				MetaCyc:ALLIIN-LYASE-RXN|RHEA:20141|EC:4.4.1.4									molecular_function											owl:Class	
GO:0004379	biolink:NamedThing	glycylpeptide N-tetradecanoyltransferase activity	Catalysis of the reaction: tetradecanoyl-CoA + glycyl-peptide = CoA + N-tetradecanoylglycyl-peptide.	tmpzr1t_l9r_go_relaxed.owl	protein N-myristoyltransferase activity|myristoyl-coenzyme A:protein N-myristoyl transferase activity|peptide N-myristoyltransferase activity|peptide N-tetradecanoyltransferase activity|N-myristoyltransferase activity|tetradecanoyl-CoA:glycylpeptide N-tetradecanoyltransferase activity|myristoylating enzymes|myristoyl-CoA-protein N-myristoyltransferase activity				MetaCyc:2.3.1.97-RXN|RHEA:15521|Reactome:R-HSA-184392|Reactome:R-HSA-2534087|EC:2.3.1.97							GO:0019106		molecular_function											owl:Class	
GO:0036139	biolink:NamedThing	peptidyl-histidine dioxygenase activity	Catalysis of the reaction: peptidyl L-histidine + 2-oxoglutarate + O2 = peptidyl hydroxy-L-histidine + succinate + CO2.	tmpzr1t_l9r_go_relaxed.owl								bf	2012-03-07T09:26:54Z					molecular_function											owl:Class	
GO:1900495	biolink:NamedThing	negative regulation of butyryl-CoA biosynthetic process from acetyl-CoA	Any process that stops, prevents or reduces the frequency, rate or extent of butyryl-CoA biosynthetic process from acetyl-CoA.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of butyryl-CoA biosynthetic process from acetyl-CoA|downregulation of butyryl-CoA biosynthesis from acetyl-CoA|inhibition of butyryl-CoA biosynthesis from acetyl-CoA|down-regulation of butyryl-CoA biosynthesis from acetyl-CoA|downregulation of butyryl-CoA biosynthetic process from acetyl-CoA|down regulation of butyryl-CoA biosynthesis from acetyl-CoA|negative regulation of butyryl-CoA biosynthesis from acetyl-CoA|down regulation of butyryl-CoA biosynthetic process from acetyl-CoA|inhibition of butyryl-CoA biosynthetic process from acetyl-CoA							tt	2012-05-02T03:51:49Z					biological_process											owl:Class	
GO:0102872	biolink:NamedThing	1-16:0-2-18:2-phosphatidylcholine desaturase activity	Catalysis of the reaction: 1-palmitoyl-2-linoleoyl-phosphatidylcholine + O2 + a reduced electron acceptor <=> 1-16:0-2-18:3-phosphatidylcholine + 2 H2O + an oxidized electron acceptor.	tmpzr1t_l9r_go_relaxed.owl					EC:1.14.19.25|MetaCyc:RXN-8361									molecular_function											owl:Class	
GO:1990771	biolink:NamedThing	clathrin-dependent extracellular exosome endocytosis	The clathrin-mediated endocytosis of an extracellular exosome.	tmpzr1t_l9r_go_relaxed.owl	clathrin-mediated extracellular exosome endocytosis|exosome related							sl	2015-06-15T17:03:57Z					biological_process											owl:Class	
GO:1903087	biolink:NamedThing	mitotic spindle pole body duplication	Any spindle pole body duplication that is involved in the mitotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl	spindle pole body biogenesis involved in mitotic cell cycle|spindle pole body assembly involved in mitotic cell cycle|spindle pole body replication involved in mitotic cell cycle|spindle pole body duplication involved in mitotic cell cycle|spindle pole body biosynthesis involved in mitotic cell cycle|spindle pole body duplication in cytoplasm involved in mitotic cell cycle|spindle pole body duplication associated with nuclear envelope involved in mitotic cell cycle|spindle pole body formation involved in mitotic cell cycle							jl	2014-06-02T16:45:56Z					biological_process											owl:Class	
GO:0019097	biolink:NamedThing	pole plasm mitochondrial srRNA localization	Any process in which mitochondrial small ribosomal RNA is transported to, or maintained in, the oocyte pole plasm. An example of this is found in Drosophila melanogaster.	tmpzr1t_l9r_go_relaxed.owl	pole plasm mitochondrial srRNA localisation|establishment and maintenance of mitochondrial localization in pole plasm|oocyte pole plasm mitochondrial srRNA localization											GO:0048119		biological_process											owl:Class	
GO:0033571	biolink:NamedThing	lactoferrin transport	The directed movement of lactoferrin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0090671	biolink:NamedThing	telomerase RNA localization to Cajal body	A process in which telomerase RNA (TERC) is transported to, or maintained in, a Cajal body.	tmpzr1t_l9r_go_relaxed.owl								tb	2015-12-17T14:06:21Z					biological_process											owl:Class	
GO:0090670	biolink:NamedThing	RNA localization to Cajal body	A process in which an RNA is transported to, or maintained in, a Cajal body.	tmpzr1t_l9r_go_relaxed.owl								tb	2015-12-17T14:04:40Z					biological_process											owl:Class	
GO:0034969	biolink:NamedThing	histone arginine methylation	The modification of a histone by addition of a methyl group to an arginine residue.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0016571	biolink:NamedThing	histone methylation	The modification of histones by addition of methyl groups.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Histone_methylation									biological_process											owl:Class	
GO:0048543	biolink:NamedThing	phytochrome chromophore biosynthetic process	The chemical reactions and pathways resulting in the formation of the phytochrome chromophore. The phytochrome chromophore is a linear tetrapyrrolic prosthetic group covalently attached to the large soluble protein phytochrome. Light absorption by the phytochrome chromophore triggers photoconversion between two spectrally distinct forms of the photoreceptor: Pr, the red light absorbing form, and Pfr, the far red light absorbing form.	tmpzr1t_l9r_go_relaxed.owl	phytochrome chromophore anabolism|phytochrome chromophore formation|phytochrome chromophore synthesis|phytochrome chromophore biosynthesis													biological_process											owl:Class	
GO:1901005	biolink:NamedThing	ubiquinone-6 catabolic process	The chemical reactions and pathways resulting in the breakdown of ubiquinone-6.	tmpzr1t_l9r_go_relaxed.owl	ubiquinone-6 breakdown|ubiquinone-6 catabolism|ubiquinone-6 degradation							bf	2012-06-15T09:59:51Z					biological_process											owl:Class	
GO:0032322	biolink:NamedThing	ubiquinone catabolic process	The chemical reactions and pathways resulting in the breakdown of ubiquinone, a lipid-soluble electron-transporting coenzyme.	tmpzr1t_l9r_go_relaxed.owl	ubiquinone breakdown|ubiquinone catabolism|ubiquinone degradation													biological_process											owl:Class	
GO:0042815	biolink:NamedThing	bipolar cell growth	The process in which a cell irreversibly increases in size along one axis through simultaneous polarized growth from opposite ends of a cell, resulting in morphogenesis of the cell.	tmpzr1t_l9r_go_relaxed.owl	polar cell elongation|bipolar cell elongation|bipolar growth					Bipolar cell growth refers to a change in both cell size and cell shape. For shape changes where cell size is not affected, consider instead the term 'establishment or maintenance of bipolar cell polarity resulting in cell shape ; GO:0061246' and its children.								biological_process											owl:Class	
GO:0072432	biolink:NamedThing	response to G1 DNA damage checkpoint signaling	A process that occurs in response to signals generated as a result of G1/S transition DNA damage checkpoint signaling.	tmpzr1t_l9r_go_relaxed.owl	mitotic cell cycle G1/S transition DNA damage checkpoint effector process|response to signal involved in mitotic cell cycle G1/S transition DNA damage checkpoint|response to mitotic cell cycle G1/S transition DNA damage checkpoint signaling							mah	2010-12-08T04:38:04Z					biological_process											owl:Class	
GO:0009297	biolink:NamedThing	pilus assembly	The assembly from its constituent parts of a pilus, a short filamentous structure of bacterial cell, flagella-like in structure and generally present in many copies. Pili are variously involved in transfer of nucleic acids, adherence to surfaces, and formation of pellicles. Is required for bacterial conjugation, or can play a role in adherence to surfaces (when it is called a fimbrium), and in the formation of pellicles.	tmpzr1t_l9r_go_relaxed.owl	fimbriae assembly|fimbrium assembly|pilus biogenesis|fimbrium biogenesis|fimbrial assembly|pilus formation|fimbria assembly|fimbria biogenesis|fimbriae biogenesis	https://github.com/geneontology/go-ontology/issues/14579												biological_process											owl:Class	
GO:0043711	biolink:NamedThing	pilus organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a pilus, a short filamentous structure on a bacterial cell, flagella-like in structure and generally present in many copies.	tmpzr1t_l9r_go_relaxed.owl	pilus organisation|pilus organization and biogenesis					Note that this term should not be used for direct annotation. Please use one of the children, GO:0009297 ; pilus assembly or GO:0043108 ; pilus retraction.								biological_process											owl:Class	
GO:0050782	biolink:NamedThing	galactose uniporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: galactose (out) = galactose(in).	tmpzr1t_l9r_go_relaxed.owl	galactose, glucose uniporter activity													molecular_function											owl:Class	
GO:0099601	biolink:NamedThing	regulation of neurotransmitter receptor activity	Any process that modulates the frequency, rate or extent of neurotransmitter receptor activity. Modulation may be via an effect on ligand affinity, or effector funtion such as ion selectivity or pore opening/closing in ionotropic receptors.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:2000497	biolink:NamedThing	positive regulation of cell proliferation involved in compound eye morphogenesis	Any process that activates or increases the frequency, rate or extent of cell proliferation involved in compound eye morphogenesis.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-03-18T02:19:54Z					biological_process											owl:Class	
GO:0071423	biolink:NamedThing	malate transmembrane transport	A process in which a malate ion is transported across a membrane.	tmpzr1t_l9r_go_relaxed.owl	transmembrane malate transport|malate membrane transport					Note that this term is not intended for use in annotating lateral movement within membranes.		mah	2009-12-15T03:31:37Z					biological_process											owl:Class	
GO:0008235	biolink:NamedThing	metalloexopeptidase activity	Catalysis of the hydrolysis of a peptide bond not more than three residues from the N- or C-terminus of a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1901355	biolink:NamedThing	response to rapamycin	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a rapamycin stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2012-09-13T13:12:26Z					biological_process											owl:Class	
GO:2001278	biolink:NamedThing	positive regulation of leucine biosynthetic process	Any process that activates or increases the frequency, rate or extent of leucine biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of leucine formation|positive regulation of leucine synthesis|positive regulation of leucine anabolism|positive regulation of leucine biosynthesis							mcc	2011-12-13T03:13:42Z					biological_process											owl:Class	
GO:1900685	biolink:NamedThing	positive regulation of fumonisin biosynthetic process	Any process that activates or increases the frequency, rate or extent of fumonisin biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	upregulation of fumonisin synthesis|positive regulation of fumonisin formation|positive regulation of fumonisin biosynthesis|up regulation of fumonisin anabolism|activation of fumonisin anabolism|up-regulation of fumonisin synthesis|up-regulation of fumonisin formation|up regulation of fumonisin biosynthetic process|upregulation of fumonisin formation|up-regulation of fumonisin biosynthetic process|up regulation of fumonisin synthesis|up regulation of fumonisin formation|positive regulation of fumonisin synthesis|up regulation of fumonisin biosynthesis|upregulation of fumonisin biosynthetic process|up-regulation of fumonisin biosynthesis|positive regulation of fumonisin anabolism|activation of fumonisin biosynthesis|upregulation of fumonisin anabolism|activation of fumonisin biosynthetic process|activation of fumonisin formation|up-regulation of fumonisin anabolism|activation of fumonisin synthesis|upregulation of fumonisin biosynthesis							di	2012-05-22T04:30:06Z					biological_process											owl:Class	
GO:0050857	biolink:NamedThing	positive regulation of antigen receptor-mediated signaling pathway	Any process that activates or increases the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a B- or T cell.	tmpzr1t_l9r_go_relaxed.owl	activation of antigen receptor-mediated signaling pathway|up regulation of antigen receptor-mediated signaling pathway|positive regulation of antigen receptor mediated signalling pathway|stimulation of antigen receptor-mediated signaling pathway|upregulation of antigen receptor-mediated signaling pathway|up-regulation of antigen receptor-mediated signaling pathway													biological_process											owl:Class	
GO:0008117	biolink:NamedThing	sphinganine-1-phosphate aldolase activity	Catalysis of the reaction: sphinganine 1-phosphate = phosphoethanolamine + palmitaldehyde.	tmpzr1t_l9r_go_relaxed.owl	sphinganine-1-phosphate palmitaldehyde-lyase (phosphoethanolamine-forming)|sphingosine-1-phosphate lyase activity|sphingosine-1-phosphate aldolase activity|sphinganine-1-phosphate lyase activity|dihydrosphingosine 1-phosphate aldolase activity|sphinganine-1-phosphate alkanal-lyase activity|sphinganine-1-phosphate palmitaldehyde-lyase activity				Reactome:R-HSA-428676|EC:4.1.2.27|RHEA:18593|Reactome:R-HSA-428681|MetaCyc:SPHINGANINE-1-PHOSPHATE-ALDOLASE-RXN							GO:0016001		molecular_function											owl:Class	
GO:1905512	biolink:NamedThing	regulation of short-term synaptic potentiation	Any process that modulates the frequency, rate or extent of short-term synaptic potentiation.	tmpzr1t_l9r_go_relaxed.owl	regulation of synaptic facilitation							hjd	2016-09-28T17:40:15Z					biological_process											owl:Class	
GO:0031077	biolink:NamedThing	post-embryonic camera-type eye development	The process occurring during the post-embryonic phase whose specific outcome is the progression of the camera-type eye over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl	post-embryonic camera-style eye development													biological_process											owl:Class	
GO:0002090	biolink:NamedThing	regulation of receptor internalization	Any process that modulates the frequency, rate or extent of receptor internalization.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0075257	biolink:NamedThing	positive regulation of teliospore formation	Any process that activates, maintains or increases the frequency, rate or extent of teliospore formation, which is the formation of a thick-walled resting or overwintering spore produced by the rust fungi (Uredinales) and smut fungi (Ustilaginales) in which karyogamy occurs.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0150165	biolink:NamedThing	miRNA-mediated inhibition of transcription by RNA polymerase II	Any process mediated by a microRNA (miRNA) that stops, prevents or reduces the frequency, rate or extent of transcription from an RNA polymerase II promoter.	tmpzr1t_l9r_go_relaxed.owl								bc	2020-01-14T12:21:12Z					biological_process											owl:Class	
GO:0090529	biolink:NamedThing	cell septum assembly	The assembly and arrangement of a cellular component that is composed of peptidoglycan and often chitin in addition to other materials and usually forms perpendicular to the long axis of a cell or hypha. It grows centripetally from the cell wall to the center of the cell and often functions in the compartmentalization of a cell into two daughter cells.	tmpzr1t_l9r_go_relaxed.owl	cell septum assembly involved in cell cycle cytokinesis							tb	2013-02-06T10:26:38Z			GO:0090530		biological_process											owl:Class	
GO:0033115	biolink:NamedThing	cyanelle thylakoid membrane	The lipid bilayer membrane of any thylakoid within a cyanelle.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0015723	biolink:NamedThing	bilirubin transport	The directed movement of bilirubin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0048799	biolink:NamedThing	animal organ maturation	A developmental process, independent of morphogenetic (shape) change, that is required for an animal organ to attain its fully functional state. An organ is a tissue or set of tissues that work together to perform a specific function or functions.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0009583	biolink:NamedThing	detection of light stimulus	The series of events in which a light stimulus (in the form of photons) is received and converted into a molecular signal.	tmpzr1t_l9r_go_relaxed.owl	perception of light|detection of light													biological_process											owl:Class	
GO:0051935	biolink:NamedThing	glutamate reuptake	The uptake of L-glutamate by neurons or glial cells. This process leads to inactivation and recycling of neurotransmitters.	tmpzr1t_l9r_go_relaxed.owl	glutamate import into glial cell|L-glutamate uptake involved in synaptic transmission|L-glutamate uptake during transmission of nerve impulse|glutamate uptake during transmission of nerve impulse|L-glutamate reuptake|glutamate recycling|glutamate import into neuron													biological_process											owl:Class	
GO:1905262	biolink:NamedThing	negative regulation of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination	Any process that stops, prevents or reduces the frequency, rate or extent of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination.	tmpzr1t_l9r_go_relaxed.owl	down regulation of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination|down-regulation of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination|inhibition of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination|downregulation of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination							se	2016-06-13T20:45:10Z					biological_process											owl:Class	
GO:0120012	biolink:NamedThing	intermembrane sphingolipid transfer	The transport of sphingolipids between membranes in which a sphingolipid molecule is transported through an aqueous phase from the outer leaflet of a donor membrane to the outer leaflet of an acceptor membrane. This process does not require metabolic energy and can be either spontaneous or mediated by lipid transfer proteins (LTPs).	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/12329						krc	2017-03-16T22:20:45Z					biological_process											owl:Class	
GO:1990466	biolink:NamedThing	protein autosumoylation	The sumoylation by a protein of one or more of its own amino acid residues, or residues on an identical protein.	tmpzr1t_l9r_go_relaxed.owl	protein self-sumoylation|protein auto-sumoylation							se	2014-08-25T22:37:21Z					biological_process											owl:Class	
GO:0016925	biolink:NamedThing	protein sumoylation	The process in which a SUMO protein (small ubiquitin-related modifier) is conjugated to a target protein via an isopeptide bond between the carboxy-terminus of SUMO with an epsilon-amino group of a lysine residue of the target protein.	tmpzr1t_l9r_go_relaxed.owl	SUMO-protein conjugation|protein sumolation|sumoylation|Smt3-protein conjugation|small ubiquitin-related protein 1 conjugation|Smt3p-protein conjugation				Wikipedia:SUMO_protein							GO:0019951|GO:0016927|GO:0006485|GO:0019947		biological_process											owl:Class	
GO:0090493	biolink:NamedThing	catecholamine uptake	The directed movement of catecholamine into a cell.	tmpzr1t_l9r_go_relaxed.owl								tb	2012-10-17T11:06:17Z					biological_process											owl:Class	
GO:0051544	biolink:NamedThing	positive regulation of elastin biosynthetic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of elastin.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of elastin biosynthetic process|upregulation of elastin biosynthetic process|up regulation of elastin biosynthetic process|activation of elastin biosynthetic process|stimulation of elastin biosynthetic process													biological_process											owl:Class	
GO:0051647	biolink:NamedThing	nucleus localization	Any process in which the nucleus is transported to, and/or maintained in, a specific location within the cell.	tmpzr1t_l9r_go_relaxed.owl	localization of nucleus|establishment and maintenance of nucleus localization|nucleus localisation|cell nucleus localization													biological_process											owl:Class	
GO:0090274	biolink:NamedThing	positive regulation of somatostatin secretion	Any process that increases the rate, frequency, extent of the regulated release of somatostatin from secretory granules in the D cells of the pancreas.	tmpzr1t_l9r_go_relaxed.owl								tb	2010-02-05T02:54:14Z					biological_process											owl:Class	
GO:1902523	biolink:NamedThing	positive regulation of protein K63-linked ubiquitination	Any process that activates or increases the frequency, rate or extent of protein K63-linked ubiquitination.	tmpzr1t_l9r_go_relaxed.owl	up regulation of protein K63-linked polyubiquitination|activation of protein K63-linked ubiquitination|activation of protein K63-linked polyubiquitination|upregulation of protein K63-linked polyubiquitination|up regulation of protein K63-linked ubiquitination|positive regulation of protein K63-linked polyubiquitination|up-regulation of protein K63-linked polyubiquitination|up-regulation of protein K63-linked ubiquitination|upregulation of protein K63-linked ubiquitination					An example is BIRC2 (UniProt ID Q13490) in PMID:21931591.		ppm	2013-12-02T09:52:05Z					biological_process											owl:Class	
GO:1990021	biolink:NamedThing	Schaffer axon collateral	Part of axon of a CA3 pyramidal neuron that projects to hippocampal area CA1.	tmpzr1t_l9r_go_relaxed.owl	Schaffer collateral				NIF_Subcellular:nlx_subcell_20090511			pr	2013-01-10T16:06:17Z					cellular_component											owl:Class	
GO:0001155	biolink:NamedThing	TFIIIA-class transcription factor binding	Binding to an RNA polymerase III transcription factor of the TFIIIA class, one of the factors involved in formation of the preinitiation complex (PIC) at RNA polymerase III promoters.	tmpzr1t_l9r_go_relaxed.owl								krc	2011-01-27T04:57:49Z					molecular_function											owl:Class	
GO:0001025	biolink:NamedThing	RNA polymerase III general transcription initiation factor binding	Binding to an RNA polymerase III transcription factor, a protein required to initiate or regulate transcription by RNA polymerase III.	tmpzr1t_l9r_go_relaxed.owl	RNA polymerase III transcription factor binding							krc	2010-08-20T03:26:50Z					molecular_function											owl:Class	
GO:0014807	biolink:NamedThing	regulation of somitogenesis	Any process that modulates the frequency, rate or extent of somitogenesis.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0045579	biolink:NamedThing	positive regulation of B cell differentiation	Any process that activates or increases the frequency, rate or extent of B cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	up regulation of B cell differentiation|positive regulation of B lymphocyte differentiation|positive regulation of B-cell differentiation|activation of B cell differentiation|positive regulation of B cell development|positive regulation of B-lymphocyte differentiation|up-regulation of B cell differentiation|stimulation of B cell differentiation|upregulation of B cell differentiation					Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.								biological_process											owl:Class	
GO:1905830	biolink:NamedThing	positive regulation of prostaglandin catabolic process	Any process that activates or increases the frequency, rate or extent of prostaglandin catabolic process.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of prostaglandin breakdown|activation of prostaglandin catabolic process|up-regulation of prostaglandin catabolism|upregulation of prostaglandin degradation|up-regulation of prostaglandin degradation|activation of prostaglandin breakdown|upregulation of prostaglandin catabolic process|upregulation of prostaglandin catabolism|positive regulation of prostaglandin catabolism|up regulation of prostaglandin breakdown|up regulation of prostaglandin catabolic process|upregulation of prostaglandin breakdown|up-regulation of prostaglandin catabolic process|activation of prostaglandin catabolism|activation of prostaglandin degradation|positive regulation of prostaglandin breakdown|up regulation of prostaglandin catabolism|up regulation of prostaglandin degradation|positive regulation of prostaglandin degradation							sl	2017-01-16T21:36:56Z					biological_process											owl:Class	
GO:0031448	biolink:NamedThing	positive regulation of fast-twitch skeletal muscle fiber contraction	Any process that activates or increases the frequency, rate or extent of fast-twitch skeletal muscle contraction.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of fast-twitch skeletal muscle contraction|stimulation of fast-twitch skeletal muscle contraction|up regulation of fast-twitch skeletal muscle contraction|positive regulation of fast-twitch skeletal muscle contraction|activation of fast-twitch skeletal muscle contraction|upregulation of fast-twitch skeletal muscle contraction													biological_process											owl:Class	
GO:2001238	biolink:NamedThing	positive regulation of extrinsic apoptotic signaling pathway	Any process that activates or increases the frequency, rate or extent of extrinsic apoptotic signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of extrinsic apoptotic signalling pathway|positive regulation of extrinsic apoptosis							pr	2011-11-24T01:30:16Z					biological_process											owl:Class	
GO:0120056	biolink:NamedThing	large intestinal transit	Migration of ingested material along the length of the large intestine.	tmpzr1t_l9r_go_relaxed.owl	large intestine transit|colon transit|large bowel transit|colonic transit							krc	2017-06-13T20:52:01Z					biological_process											owl:Class	
GO:0120054	biolink:NamedThing	intestinal motility	Contractions of the intestinal tract that include peristalsis (moving contents onward) and non-peristaltic movement (moving contents back and forth).	tmpzr1t_l9r_go_relaxed.owl								krc	2017-06-13T20:42:24Z					biological_process											owl:Class	
GO:0040016	biolink:NamedThing	embryonic cleavage	The first few specialized divisions of an activated animal egg.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0047047	biolink:NamedThing	oxaloglycolate reductase (decarboxylating) activity	Catalysis of the reaction: glycerate + CO2 + NAD(P)+ = NAD(P)H + H+ + 2-hydroxy-3-oxosuccinate.	tmpzr1t_l9r_go_relaxed.owl	D-glycerate:NAD(P)+ oxidoreductase (carboxylating)				MetaCyc:1.1.1.92-RXN|EC:1.1.1.92									molecular_function											owl:Class	
GO:0034610	biolink:NamedThing	oligodeoxyribonucleotidase activity	Catalysis of the exonucleolytic cleavage of oligodeoxyribonucleotides to yield deoxyribonucleoside 5'-phosphates.	tmpzr1t_l9r_go_relaxed.owl	DNA oligonucleotidase activity													molecular_function											owl:Class	
GO:0140502	biolink:NamedThing	effector-mediated suppression of host salicylic acid-mediated innate immune signalling	A process mediated by a molecule secreted by a symbiont that results in the suppression of host salicylic acid-mediated innate immune signalling.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/19848						pg	2020-08-11T06:16:36Z					biological_process											owl:Class	
GO:0052003	biolink:NamedThing	suppression by symbiont of defense-related host salicylic acid-mediated signal transduction pathway	Any process in which a symbiont stops, prevents, or reduces the frequency, rate or extent of host salicylic acid-mediated signal transduction pathways during the host defense response. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	down regulation by symbiont of host salicylic acid-mediated defense response|inhibition by symbiont of host salicylic acid-mediated defense response|negative modulation by organism of defense-related host salicylic acid-mediated signal transduction pathway|suppression of host SA mediated defense response|downregulation by symbiont of defense-related host salicylic acid-mediated signal transduction pathway|down-regulation by symbiont of defense-related host salicylic acid-mediated signal transduction pathway|down regulation by symbiont of defense-related host salicylic acid-mediated signal transduction pathway|downregulation by symbiont of host salicylic acid-mediated defense response|down-regulation by symbiont of host salicylic acid-mediated defense response|negative regulation by symbiont of defense-related host salicylic acid-mediated signal transduction pathway|negative modulation by organism of defense-related host SA-mediated signal transduction pathway|inhibition by symbiont of defense-related host salicylic acid-mediated signal transduction pathway|negative regulation by organism of defense-related salicylic acid-mediated signal transduction pathway of other organism involved in symbiotic interaction|negative regulation by organism of defense-related host SA-mediated signal transduction pathway|negative regulation of host SA-mediated defense response|negative regulation by symbiont of host salicylic acid-mediated defense response|negative regulation by organism of salicylic acid-mediated defense response of other organism involved in symbiotic interaction|suppression by organism of host salicylic acid-mediated defense response											GO:0052004|GO:0052252|GO:0052253		biological_process											owl:Class	
GO:1901443	biolink:NamedThing	negative regulation of response to furfural	Any process that stops, prevents or reduces the frequency, rate or extent of response to furfural.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of response to furfural|inhibition of response to furfural|down regulation of response to furfural|downregulation of response to furfural							tt	2012-10-02T14:10:34Z					biological_process											owl:Class	
GO:1904049	biolink:NamedThing	negative regulation of spontaneous neurotransmitter secretion	Any process that stops, prevents or reduces the frequency, rate or extent of spontaneous neurotransmitter secretion.	tmpzr1t_l9r_go_relaxed.owl	inhibition of stimulus-independent neurotransmitter secretion|down-regulation of spontaneous neurotransmitter secretion|down regulation of stimulus-independent neurotransmitter secretion|downregulation of spontaneous neurotransmitter secretion|down regulation of spontaneous neurotransmitter secretion|inhibition of spontaneous neurotransmitter secretion|down-regulation of stimulus-independent neurotransmitter secretion|negative regulation of stimulus-independent neurotransmitter secretion|downregulation of stimulus-independent neurotransmitter secretion					An example of this is PARK2 / parkin in human (O60260) in PMID:22314364 (inferred from mutant phenotype).		pad	2015-03-17T10:37:17Z					biological_process											owl:Class	
GO:0140572	biolink:NamedThing	vacuole fission	The division of a vacuole within a cell to form two or more separate vacuoles.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/20639						pg	2021-01-04T10:17:58Z					biological_process											owl:Class	
GO:0048285	biolink:NamedThing	organelle fission	The creation of two or more organelles by division of one organelle.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0071525	biolink:NamedThing	pyrrolysine metabolic process	The chemical reactions and pathways involving pyrrolysine, N6-{[(2R,3R)-3-methyl-3,4-dihydro-2H-pyrrol-2-yl]carbonyl}-L-lysine.	tmpzr1t_l9r_go_relaxed.owl	pyrrolysine metabolism|monomethylamine methyltransferase cofactor lysine adduct metabolic process							mah	2010-01-07T02:44:49Z					biological_process											owl:Class	
GO:0097141	biolink:NamedThing	BIM-BCL-2 complex	A heterodimeric protein complex consisting of BIM and BCL-2, members of the Bcl-2 family of anti- and proapoptotic regulators.	tmpzr1t_l9r_go_relaxed.owl								pr	2011-08-02T01:42:31Z					cellular_component											owl:Class	
GO:0006114	biolink:NamedThing	glycerol biosynthetic process	The chemical reactions and pathways resulting in the formation of glycerol, 1,2,3-propanetriol, a sweet, hygroscopic, viscous liquid, widely distributed in nature as a constituent of many lipids.	tmpzr1t_l9r_go_relaxed.owl	glycerol formation|glycerol biosynthesis|glycerol synthesis|glycerol anabolism													biological_process											owl:Class	
GO:0042403	biolink:NamedThing	thyroid hormone metabolic process	The chemical reactions and pathways involving any of the compounds secreted by the thyroid gland, largely thyroxine and triiodothyronine.	tmpzr1t_l9r_go_relaxed.owl	thyroid hormone metabolism													biological_process											owl:Class	
GO:1901911	biolink:NamedThing	adenosine 5'-(hexahydrogen pentaphosphate) catabolic process	The chemical reactions and pathways resulting in the breakdown of adenosine 5'-(hexahydrogen pentaphosphate).	tmpzr1t_l9r_go_relaxed.owl	adenosine 5'-(hexahydrogen pentaphosphate) breakdown|adenosine 5'-(hexahydrogen pentaphosphate) catabolism|adenosine 5'-(hexahydrogen pentaphosphate) degradation							al	2013-02-13T14:18:03Z					biological_process											owl:Class	
GO:0008979	biolink:NamedThing	prophage integrase activity	Catalysis of the integration of prophage DNA into a target DNA molecule, usually a bacterial chromosome, via a sequence-specific recombination event which involves the formation of an intasome, a DNA-protein-complex designed for site-specific recombination of the phage and host DNA.	tmpzr1t_l9r_go_relaxed.owl	integrase activity involved in establishment of integrated proviral latency													molecular_function											owl:Class	
GO:0001841	biolink:NamedThing	neural tube formation	The formation of a tube from the flat layer of ectodermal cells known as the neural plate. This will give rise to the central nervous system.	tmpzr1t_l9r_go_relaxed.owl	neurulation|neural tube morphogenesis				Wikipedia:Neurulation							GO:0001679		biological_process											owl:Class	
GO:0001838	biolink:NamedThing	embryonic epithelial tube formation	The morphogenesis of an embryonic epithelium into a tube-shaped structure.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0035785	biolink:NamedThing	cellular nickel ion homeostasis	Any process involved in the maintenance of an internal steady state of nickel ions at the level of a cell.	tmpzr1t_l9r_go_relaxed.owl	cellular nickel homeostasis							bf	2011-04-05T09:55:56Z					biological_process											owl:Class	
GO:0072503	biolink:NamedThing	cellular divalent inorganic cation homeostasis	Any process involved in the maintenance of an internal steady state of divalent cations at the level of a cell.	tmpzr1t_l9r_go_relaxed.owl						Note that this term was split from 'cellular di-, tri-valent inorganic cation homeostasis ; GO:0030005' (sibling term 'cellular trivalent inorganic cation homeostasis' ; GO:0072504').		mah	2010-12-16T01:25:40Z					biological_process											owl:Class	
GO:0036527	biolink:NamedThing	peptidyl-arginine deglycation	The removal of a sugar or dicarbonyl from an arginine residue of a glycated protein.	tmpzr1t_l9r_go_relaxed.owl	deglycation of N-acetylarginine							bf	2016-08-04T10:36:30Z					biological_process											owl:Class	
GO:0035627	biolink:NamedThing	ceramide transport	The directed movement of ceramides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Ceramides are a class of lipid composed of sphingosine linked to a fatty acid.	tmpzr1t_l9r_go_relaxed.owl								bf	2010-12-10T10:02:16Z					biological_process											owl:Class	
GO:0046449	biolink:NamedThing	creatinine metabolic process	The chemical reactions and pathways involving creatinine, 2-amino-1,5-dihydro-1-methyl-4H-imidazol-4-one, an end product of creatine metabolism and a normal constituent of urine.	tmpzr1t_l9r_go_relaxed.owl	creatinine metabolism													biological_process											owl:Class	
GO:0047660	biolink:NamedThing	amidinoaspartase activity	Catalysis of the reaction: N-amidino-L-aspartate + H(2)O = L-aspartate + urea.	tmpzr1t_l9r_go_relaxed.owl	N-amidino-L-aspartate amidinohydrolase activity|amidinoaspartic amidinohydrolase activity				EC:3.5.3.14|MetaCyc:AMIDINOASPARTASE-RXN|KEGG_REACTION:R00777|RHEA:14849									molecular_function											owl:Class	
GO:1900350	biolink:NamedThing	positive regulation of methane biosynthetic process from methylamine	Any process that activates or increases the frequency, rate or extent of methane biosynthetic process from methylamine.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of methane biosynthetic process from methylamine|upregulation of methane biosynthetic process from methylamine|activation of methane biosynthetic process from methylamine|up regulation of methane biosynthetic process from methylamine							tt	2012-04-06T02:12:12Z					biological_process											owl:Class	
GO:0032400	biolink:NamedThing	melanosome localization	Any process in which a melanosome is transported to, and/or maintained in, a specific location within the cell.	tmpzr1t_l9r_go_relaxed.owl	melanosome localisation													biological_process											owl:Class	
GO:0099002	biolink:NamedThing	viral genome ejection through host cell envelope, short tail mechanism	Ejection by a non-enveloped prokaryotic virus of its genome into the host cytoplasm via a short tail ejection system consisting a central tube, the connector which attaches the tail to the phage capsid and releases inner core proteins.  Upon binding to the host cell surface, the phage displays a tube-like extension of its short tail that penetrates both host membranes. This tail extension comes from the release of viral core proteins with channel forming properties.	tmpzr1t_l9r_go_relaxed.owl	viral short tail ejection system				VZ:3954									biological_process											owl:Class	
GO:0039678	biolink:NamedThing	viral genome ejection through host cell envelope	Ejection by a non-enveloped prokaryotic virus of its genome into the host cytoplasm. Caudovirales carry an ejection apparatus that can be long and contractile, long and noncontractile, or short, and is able to penetrate the host cell envelope to deliver the viral genome into the host cell cytoplasm.	tmpzr1t_l9r_go_relaxed.owl	phage genome ejection|viral genome injection through bacterial membranes					When a pore-forming protein is involved, see also 'pore-mediated entry of viral genome into host cell ; GO:0044694'.		bf	2013-09-26T11:56:48Z					biological_process											owl:Class	
GO:0033850	biolink:NamedThing	Z-farnesyl diphosphate synthase activity	Catalysis of the reaction: geranyl diphosphate + isopentenyl diphosphate = 2-cis,6-trans-farnesyl diphosphate + diphosphate.	tmpzr1t_l9r_go_relaxed.owl	(Z)-farnesyl diphosphate synthase activity|geranyl-diphosphate:isopentenyl-diphosphate geranylcistransferase activity				MetaCyc:2.5.1.68-RXN|RHEA:23300|EC:2.5.1.68|KEGG_REACTION:R08528									molecular_function											owl:Class	
GO:1901884	biolink:NamedThing	4-hydroxycoumarin biosynthetic process	The chemical reactions and pathways resulting in the formation of 4-hydroxycoumarin.	tmpzr1t_l9r_go_relaxed.owl	4-hydroxycoumarin anabolism|4-hydroxycoumarin formation|4-hydroxycoumarin synthesis|4-hydroxycoumarin biosynthesis							ms	2013-02-06T14:05:59Z					biological_process											owl:Class	
GO:1901882	biolink:NamedThing	4-hydroxycoumarin metabolic process	The chemical reactions and pathways involving 4-hydroxycoumarin.	tmpzr1t_l9r_go_relaxed.owl	4-hydroxycoumarin metabolism							ms	2013-02-06T14:05:50Z					biological_process											owl:Class	
GO:0050581	biolink:NamedThing	D-mannitol oxidase activity	Catalysis of the reaction: mannitol + O2 = mannose + H2O2.	tmpzr1t_l9r_go_relaxed.owl	mannitol oxidase activity|D-arabitol oxidase activity|mannitol:oxygen oxidoreductase (cyclizing)|D-arabinitol oxidase activity				EC:1.1.3.40|RHEA:18513|MetaCyc:1.1.3.40-RXN									molecular_function											owl:Class	
GO:0021911	biolink:NamedThing	retinoic acid metabolic process in spinal cord anterior-posterior patterning	The chemical reactions and pathways involving the synthesis and degradation of retionic acid that results in the spatial identity of regions along the anterior-posterior axis of the spinal cord.	tmpzr1t_l9r_go_relaxed.owl	retinoic acid metabolism in spinal cord anterior-posterior patterning													biological_process											owl:Class	
GO:0098705	biolink:NamedThing	copper ion import across plasma membrane	The directed movement of copper ions from outside of a cell, across the plasma membrane and into the cytosol.	tmpzr1t_l9r_go_relaxed.owl	copper cation import into cell|high affinity copper transport|high affinity copper ion transport|copper ion import into cell|high-affinity copper ion transport							mah	2014-04-03T13:26:04Z			GO:0015678|GO:1902861		biological_process											owl:Class	
GO:0015679	biolink:NamedThing	plasma membrane copper ion transport	The directed movement of copper ions across the plasma membrane.	tmpzr1t_l9r_go_relaxed.owl	plasma membrane copper transport													biological_process											owl:Class	
GO:1904045	biolink:NamedThing	cellular response to aldosterone	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an aldosterone stimulus.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-03-16T23:07:59Z					biological_process											owl:Class	
GO:0009938	biolink:NamedThing	negative regulation of gibberellic acid mediated signaling pathway	Any process that stops, prevents, or reduces the frequency, rate or extent of gibberellic acid mediated signaling activity.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of gibberellic acid mediated signalling|down-regulation of gibberellic acid mediated signaling|inhibition of gibberellic acid mediated signaling|downregulation of gibberellic acid mediated signaling|down regulation of gibberellic acid mediated signaling													biological_process											owl:Class	
GO:0005019	biolink:NamedThing	platelet-derived growth factor beta-receptor activity	Combining with platelet-derived growth factor isoform PDGF-BB or PDGF-AB to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	betaPDGF receptor activity|PDGF beta-receptor activity													molecular_function											owl:Class	
GO:0005017	biolink:NamedThing	platelet-derived growth factor-activated receptor activity	Combining with platelet-derived growth factor and transmitting the signal across the plasma membrane to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	PDGF-activated receptor activity|PDGF receptor activity|PDGFR activity|platelet-derived growth factor receptor activity					Note that this term represents an activity and not a gene product, and should only be used when the receptor binds the ligand PDGF. For receptors that bind other growth factors, consider annotating to other terms under 'transmembrane signaling receptor activity ; GO:0004888.								molecular_function											owl:Class	
GO:2001004	biolink:NamedThing	negative regulation of pectin catabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of pectin catabolic process.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of pectin catabolism|negative regulation of pectin degradation|negative regulation of pectin breakdown							tt	2011-08-08T03:24:06Z					biological_process											owl:Class	
GO:0008657	biolink:NamedThing	DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) inhibitor activity	Binds to and stops, prevents or reduces the activity of ATP-hydrolyzing DNA topoisomerase. ATP-hydrolyzing DNA topoisomerase catalyzes the DNA topological transformation by transiently cleaving a pair of complementary DNA strands to form a gate through which a second double-stranded DNA segment is passed, after which the severed strands in the first DNA segment are rejoined; product release is coupled to ATP binding and hydrolysis; changes the linking number in multiples of 2.	tmpzr1t_l9r_go_relaxed.owl	DNA gyrase inhibitor activity													molecular_function											owl:Class	
GO:0072586	biolink:NamedThing	DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) regulator activity	Binds to and modulates the activity of ATP-hydrolyzing DNA topoisomerase. DNA topoisomerase (ATP-hydrolyzing) regulator activity catalyzes a DNA topological transformation by transiently cleaving a pair of complementary DNA strands to form a gate through which a second double-stranded DNA segment is passed, after which the severed strands in the first DNA segment are rejoined; product release is coupled to ATP binding and hydrolysis; changes the linking number in multiples of 2.	tmpzr1t_l9r_go_relaxed.owl								mah	2011-02-09T05:31:50Z					molecular_function											owl:Class	
GO:0050757	biolink:NamedThing	thymidylate synthase biosynthetic process	The chemical reactions and pathways resulting in the formation of the enzyme thymidylate synthase, which catalyzes the reaction: 5,10-methylenetetrahydrofolate + dUMP = dihydrofolate + dTMP.	tmpzr1t_l9r_go_relaxed.owl	thymidylate synthase anabolism|thymidylate synthase formation|thymidylate synthase synthesis|thymidylate synthase biosynthesis													biological_process											owl:Class	
GO:0006218	biolink:NamedThing	uridine catabolic process	The chemical reactions and pathways resulting in the breakdown of uridine, uracil riboside, a ribonucleoside very widely distributed but occurring almost entirely as phosphoric esters in ribonucleotides and ribonucleic acids.	tmpzr1t_l9r_go_relaxed.owl	uridine catabolism|uridine degradation|uridine breakdown													biological_process											owl:Class	
GO:0050963	biolink:NamedThing	detection of electrical stimulus involved in sensory perception	The series of events in which an electrical stimulus is received by a cell and converted into a molecular signal as part of sensory perception.	tmpzr1t_l9r_go_relaxed.owl	sensory detection of electrical stimulus during sensory perception|sensory perception, sensory transduction of electrical stimulus|sensory detection of electrical stimulus|sensory transduction of electrical stimulus during sensory perception|sensory perception, sensory detection of electrical stimulus|sensory transduction of electrical stimulus													biological_process											owl:Class	
GO:0006279	biolink:NamedThing	premeiotic DNA replication	The replication of DNA that precedes meiotic cell division.	tmpzr1t_l9r_go_relaxed.owl	DNA replication involved in S-phase involved in meiotic cell cycle|meiotic nuclear cell cycle DNA replication|premeiotic DNA synthesis|DNA replication involved in S phase involved in meiotic cell cycle|meiotic DNA replication|DNA replication during S phase involved in meiotic cell cycle|meiotic cell cycle DNA replication|meiotic DNA synthesis|nuclear cell cycle DNA replication involved in meiotic cell cycle											GO:1902968		biological_process											owl:Class	
GO:0042925	biolink:NamedThing	benzoate transmembrane transporter activity	Enables the directed movement of benzoate, the anion of benzoic acid (benzenecarboxylic acid) from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	benzoate transporter activity				RHEA:32811									molecular_function											owl:Class	
GO:0060612	biolink:NamedThing	adipose tissue development	The process whose specific outcome is the progression of adipose tissue over time, from its formation to the mature structure. Adipose tissue is specialized tissue that is used to store fat.	tmpzr1t_l9r_go_relaxed.owl	adipogenesis							dph	2009-05-15T12:36:28Z					biological_process											owl:Class	
GO:0045672	biolink:NamedThing	positive regulation of osteoclast differentiation	Any process that activates or increases the frequency, rate or extent of osteoclast differentiation.	tmpzr1t_l9r_go_relaxed.owl	upregulation of osteoclast differentiation|stimulation of osteoclast differentiation|activation of osteoclast differentiation|up regulation of osteoclast differentiation|up-regulation of osteoclast differentiation													biological_process											owl:Class	
GO:0009604	biolink:NamedThing	detection of symbiotic bacterium	The series of events in which a stimulus from a symbiotic bacterium, a bacterium living in close physical association with another organism, is received and converted into a molecular signal.	tmpzr1t_l9r_go_relaxed.owl	perception of symbiotic bacterium|detection of symbiotic bacteria|perception of symbiotic bacteria													biological_process											owl:Class	
GO:0015653	biolink:NamedThing	glycine betaine:proton symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glycine betaine(out) + H+(out) = glycine betaine(in) + H+(in).	tmpzr1t_l9r_go_relaxed.owl	glycine betaine:hydrogen symporter activity													molecular_function											owl:Class	
GO:0015199	biolink:NamedThing	amino-acid betaine transmembrane transporter activity	Enables the transfer of betaine from one side of a membrane to the other. Betaine is the N-trimethyl derivative of an amino acid.	tmpzr1t_l9r_go_relaxed.owl	glycine betaine/proline porter activity|proline/glycine/betaine:hydrogen/sodium symporter activity|betaine/GABA:sodium symporter activity|betaine transmembrane transporter activity													molecular_function											owl:Class	
GO:1903481	biolink:NamedThing	negative regulation of actin filament organization involved in mitotic actomyosin contractile ring assembly	Any process that stops, prevents or reduces the frequency, rate or extent of actin filament organization involved in mitotic actomyosin contractile ring assembly.	tmpzr1t_l9r_go_relaxed.owl	downregulation of actin filament organisation involved in contractile ring assembly involved in mitotic cytokinesis|down-regulation of actin filament organization involved in mitotic actomyosin contractile ring assembly|down regulation of actin filament organisation involved in mitotic actomyosin contractile ring assembly|inhibition of actin filament organisation involved in mitotic actomyosin contractile ring assembly|downregulation of actin filament organization involved in mitotic actomyosin contractile ring assembly|down regulation of actin filament organisation involved in contractile ring assembly involved in mitotic cytokinesis|down-regulation of actin filament organisation involved in contractile ring assembly involved in mitotic cytokinesis|negative regulation of actin filament organisation involved in contractile ring assembly involved in mitotic cytokinesis|inhibition of actin filament organization involved in mitotic actomyosin contractile ring assembly|downregulation of actin filament organisation involved in mitotic actomyosin contractile ring assembly|negative regulation of actin filament organisation involved in mitotic actomyosin contractile ring assembly|inhibition of actin filament organisation involved in contractile ring assembly involved in mitotic cytokinesis|down-regulation of actin filament organisation involved in mitotic actomyosin contractile ring assembly|down regulation of actin filament organization involved in mitotic actomyosin contractile ring assembly							vw	2014-09-23T16:03:50Z					biological_process											owl:Class	
GO:1902543	biolink:NamedThing	negative regulation of protein localization to mitotic spindle pole body	Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to mitotic spindle pole body.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of protein localisation in mitotic spindle pole body|downregulation of protein localisation to mitotic spindle pole body|downregulation of protein localization to mitotic spindle pole body|down-regulation of protein localisation to mitotic spindle pole body|inhibition of protein localisation to mitotic spindle pole body|down-regulation of protein localization to mitotic spindle pole body|down regulation of protein localisation to mitotic spindle pole body|inhibition of protein localization to mitotic spindle pole body|negative regulation of protein localisation to mitotic spindle pole body|down regulation of protein localization to mitotic spindle pole body							al	2013-12-04T13:47:18Z					biological_process											owl:Class	
GO:1902542	biolink:NamedThing	regulation of protein localization to mitotic spindle pole body	Any process that modulates the frequency, rate or extent of protein localization to mitotic spindle pole body.	tmpzr1t_l9r_go_relaxed.owl	regulation of protein localisation to mitotic spindle pole body							al	2013-12-04T13:47:09Z					biological_process											owl:Class	
GO:0080050	biolink:NamedThing	regulation of seed development	Any process that modulates the frequency, rate or extent of seed development.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0098995	biolink:NamedThing	disruption by virus of host envelope lipopolysaccharide during virus entry	The breakdown of lipopolysaccharides in a host cell envelope during virus entry into a host cell.  For example a phage entering a gram-negative bacterium may actively break down outer membrane lipopolysaccharides.	tmpzr1t_l9r_go_relaxed.owl	degradation of host cell envelope lipopolysaccharide during viral entry|disassembly by virus of outer membrane lipopolysaccharide during viral entry|degradation of host lipopolysaccharide during virus entry				VZ:3939									biological_process											owl:Class	
GO:0052009	biolink:NamedThing	disruption by symbiont of host cell wall	A process carried out by a symbiont that breaks down the cell wall of its host. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	disassembly by symbiont of host cell wall													biological_process											owl:Class	
GO:0031128	biolink:NamedThing	developmental induction	A developmental process involving two tissues in which one tissue (the inducer) produces a signal that directs cell fate commitment of cells in the second tissue (the responder).	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0043337	biolink:NamedThing	CDP-diacylglycerol-phosphatidylglycerol phosphatidyltransferase activity	Catalysis of the reaction: CDP-diacylglycerol + phosphatidylglycerol = CMP + diphosphatidylglycerol.	tmpzr1t_l9r_go_relaxed.owl	cardiolipin synthetase|cardiolipin synthase				MetaCyc:RXN-8141|Reactome:R-HSA-1483063|RHEA:32931									molecular_function											owl:Class	
GO:0036424	biolink:NamedThing	L-phosphoserine phosphatase activity	Catalysis of the reaction: O-phospho-L-serine + H2O = L-serine + phosphate, on a free amino acid.	tmpzr1t_l9r_go_relaxed.owl	O-phosphoserine phosphohydrolase activity|phosphoserine phosphatase activity	https://github.com/geneontology/go-ontology/issues/21638|https://github.com/geneontology/go-ontology/issues/20587			Reactome:R-HSA-977324|RHEA:21208|MetaCyc:RXN0-5114|KEGG_REACTION:R00582|EC:3.1.3.3|MetaCyc:PSERPHOSPHA-RXN	Do not confuse with protein phosphatases. For protein phosphatases, consider GO:0004722 ; protein serine/threonine phosphatase activity or GO:0008138 ; protein tyrosine/serine/threonine phosphatase activity.		bf	2013-09-16T13:01:03Z			GO:0004647		molecular_function											owl:Class	
GO:0102134	biolink:NamedThing	(22S)-22-hydroxy-campesterol C-23 hydroxylase activity	Catalysis of the reaction: H+ + (22S)-22-hydroxycampesterol + NADPH + O2 <=> (22R,23R)-22,23-dihydroxycampesterol + NADP + H2O.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-11529									molecular_function											owl:Class	
GO:0043949	biolink:NamedThing	regulation of cAMP-mediated signaling	Any process which modulates the frequency, rate or extent of cAMP-mediated signaling, a series of molecular signals in which a cell uses cyclic AMP to convert an extracellular signal into a response.	tmpzr1t_l9r_go_relaxed.owl	regulation of cAMP-mediated signalling													biological_process											owl:Class	
GO:0051894	biolink:NamedThing	positive regulation of focal adhesion assembly	Any process that activates or increases the frequency, rate or extent of focal adhesion assembly, the establishment and maturation of focal adhesions.	tmpzr1t_l9r_go_relaxed.owl	activation of focal adhesion formation|stimulation of focal adhesion formation|up-regulation of focal adhesion formation|upregulation of focal adhesion formation|up regulation of focal adhesion formation													biological_process											owl:Class	
GO:0032955	biolink:NamedThing	regulation of division septum assembly	Any process that modulates the frequency, rate or extent of division septum formation. Division septum formation is the assembly and arrangement of a septum that spans the plasma membrane interface between progeny cells following cytokinesis.	tmpzr1t_l9r_go_relaxed.owl	regulation of division septum formation											GO:1902468|GO:1901138		biological_process											owl:Class	
GO:0001925	biolink:NamedThing	negative regulation of B-1 B cell differentiation	Any process that stops, prevents, or reduces the rate of B-1 B cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of B-1 B cell differentiation|down regulation of B-1 B cell differentiation|inhibition of B-1 B cell differentiation|downregulation of B-1 B cell differentiation|negative regulation of B-1 B-lymphocyte differentiation|negative regulation of B-1 B-cell differentiation|negative regulation of B-1 B cell development|negative regulation of B-1 B lymphocyte differentiation					Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.								biological_process											owl:Class	
GO:0010544	biolink:NamedThing	negative regulation of platelet activation	Any process that decreases the rate or frequency of platelet activation. Platelet activation is a series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1900454	biolink:NamedThing	positive regulation of long-term synaptic depression	Any process that activates or increases the frequency, rate or extent of long term synaptic depression.	tmpzr1t_l9r_go_relaxed.owl	activation of LTD|upregulation of LTD|up-regulation of long term depression|activation of long term synaptic depression|up-regulation of long term synaptic depression|upregulation of long term depression|up regulation of long term synaptic depression|upregulation of long term synaptic depression|up regulation of long term depression|positive regulation of long term depression|up-regulation of LTD|up regulation of LTD|positive regulation of long term synaptic depression|positive regulation of LTD|activation of long term depression							rl	2012-04-27T03:55:23Z					biological_process											owl:Class	
GO:0046998	biolink:NamedThing	(S)-usnate reductase activity	Catalysis of the reaction: (6R)-2-acetyl-6-(3-acetyl-2,4,6-trihydroxy-5-methylphenyl)-3-hydroxy-6-methylcyclohexa-2,4-dien-1-one + NAD(+) = (S)-usnate + 2 H(+) + NADH.	tmpzr1t_l9r_go_relaxed.owl	reduced-(S)-usnate:NAD+ oxidoreductase (ether-bond-forming)|L-usnic acid dehydrogenase activity				KEGG_REACTION:R07345|RHEA:21876|EC:1.1.1.199|MetaCyc:1.1.1.199-RXN									molecular_function											owl:Class	
GO:0055008	biolink:NamedThing	cardiac muscle tissue morphogenesis	The process in which the anatomical structures of cardiac muscle tissue are generated and organized.	tmpzr1t_l9r_go_relaxed.owl	heart muscle morphogenesis|myocardium morphogenesis													biological_process											owl:Class	
GO:0099637	biolink:NamedThing	neurotransmitter receptor transport	The directed movement of neurotransmitter receptors.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0009628	biolink:NamedThing	response to abiotic stimulus	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abiotic (not derived from living organisms) stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to abiotic stress	https://github.com/geneontology/go-ontology/issues/16572				Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.								biological_process											owl:Class	
GO:0050849	biolink:NamedThing	negative regulation of calcium-mediated signaling	Any process that stops, prevents, or reduces the frequency, rate or extent of calcium-mediated signaling.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of calcium-mediated signaling|inhibition of calcium-mediated signaling|downregulation of calcium-mediated signaling|negative regulation of calcium-mediated signalling|down regulation of calcium-mediated signaling													biological_process											owl:Class	
GO:1901014	biolink:NamedThing	3alpha(S)-strictosidine catabolic process	The chemical reactions and pathways resulting in the breakdown of 3alpha(S)-strictosidine.	tmpzr1t_l9r_go_relaxed.owl	3alpha(S)-strictosidine catabolism|3alpha(S)-strictosidine breakdown|3alpha(S)-strictosidine degradation							yaf	2012-06-15T10:47:19Z					biological_process											owl:Class	
GO:1901013	biolink:NamedThing	3alpha(S)-strictosidine metabolic process	The chemical reactions and pathways involving 3alpha(S)-strictosidine.	tmpzr1t_l9r_go_relaxed.owl	3alpha(S)-strictosidine metabolism							yaf	2012-06-15T10:46:57Z					biological_process											owl:Class	
GO:1902668	biolink:NamedThing	negative regulation of axon guidance	Any process that stops, prevents or reduces the frequency, rate or extent of axon guidance.	tmpzr1t_l9r_go_relaxed.owl	down regulation of axon growth cone guidance|inhibition of axon growth cone guidance|down-regulation of axon growth cone guidance|downregulation of axon chemotaxis|down regulation of axon chemotaxis|negative regulation of axon pathfinding|downregulation of axon guidance|negative regulation of axon growth cone guidance|downregulation of axon pathfinding|downregulation of axon growth cone guidance|down-regulation of axon guidance|down-regulation of axon pathfinding|inhibition of axon guidance|negative regulation of axon chemotaxis|down-regulation of axon chemotaxis|inhibition of axon pathfinding|down regulation of axon pathfinding|inhibition of axon chemotaxis|down regulation of axon guidance							hjd	2014-01-31T18:50:19Z					biological_process											owl:Class	
GO:2001014	biolink:NamedThing	regulation of skeletal muscle cell differentiation	Any process that modulates the frequency, rate or extent of skeletal muscle cell differentiation.	tmpzr1t_l9r_go_relaxed.owl								yaf	2011-08-11T08:54:37Z					biological_process											owl:Class	
GO:0018810	biolink:NamedThing	trans-4-[2-(3-hydroxy)-thionaphthenyl]-2-oxo-3-butenoate hydratase activity	Catalysis of the reaction: trans-4-(2-(3-hydroxy)-thionaphthenyl)-2-oxo-3-butenoate + H2O = pyruvate + 3-hydroxy-2-formylbenzothiophene.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0164									molecular_function											owl:Class	
GO:1905116	biolink:NamedThing	positive regulation of lateral attachment of mitotic spindle microtubules to kinetochore	Any process that activates or increases the frequency, rate or extent of lateral attachment of mitotic spindle microtubules to kinetochore.	tmpzr1t_l9r_go_relaxed.owl	activation of lateral attachment of mitotic spindle microtubules to kinetochore|up-regulation of lateral attachment of mitotic spindle microtubules to kinetochore|up regulation of lateral attachment of mitotic spindle microtubules to kinetochore|upregulation of lateral attachment of mitotic spindle microtubules to kinetochore							al	2016-04-07T14:25:34Z					biological_process											owl:Class	
GO:0062164	biolink:NamedThing	regulation of pseudohyphal septin ring assembly	Any process that modulates the rate, frequency or extent of pseudohyphal septin ring assembly.	tmpzr1t_l9r_go_relaxed.owl								dph	2019-11-07T15:52:20Z					biological_process											owl:Class	
GO:0010959	biolink:NamedThing	regulation of metal ion transport	Any process that modulates the frequency, rate, or extent of metal ion transport. Metal ion transport is the directed movement of metal ions, any metal ion with an electric charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-05-06T11:40:55Z					biological_process											owl:Class	
GO:0051882	biolink:NamedThing	mitochondrial depolarization	The process in which the potential difference across the mitochondrial membrane is reduced from its steady state level.	tmpzr1t_l9r_go_relaxed.owl	mitochondrion depolarization|mitochondrial depolarisation|mitochondrial membrane depolarization|mitochondria depolarization													biological_process											owl:Class	
GO:0036482	biolink:NamedThing	neuron intrinsic apoptotic signaling pathway in response to hydrogen peroxide	A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a neuron in response to hydrogen peroxide.	tmpzr1t_l9r_go_relaxed.owl	H2O2-induced neuron intrinsic apoptotic signaling pathway|neuron intrinsic apoptotic signaling pathway in response to H2O2|neuron apoptosis in response to hydrogen peroxide|hydrogen peroxide-induced neuronal apoptosis|hydrogen peroxide-induced neuron apoptosis							bf	2014-08-14T13:23:32Z					biological_process											owl:Class	
GO:0036480	biolink:NamedThing	neuron intrinsic apoptotic signaling pathway in response to oxidative stress	A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a neuron. The pathway is induced in response to oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, and ends when the execution phase of apoptosis is triggered.	tmpzr1t_l9r_go_relaxed.owl	oxidative stress-induced neuronal apoptosis|neuron apoptosis in response to oxidative stress|oxidative stress-induced neuron apoptosis							bf	2014-08-14T13:13:44Z					biological_process											owl:Class	
GO:0031545	biolink:NamedThing	peptidyl-proline 4-dioxygenase activity	Catalysis of the reaction: peptidyl L-proline + 2-oxoglutarate + O2 = peptidyl trans-4-hydroxy-L-proline + succinate + CO2.	tmpzr1t_l9r_go_relaxed.owl	HIF-type prolyl 4-hydroxylase|prolyl 4-hydroxylase				Reactome:R-HSA-1234179|Reactome:R-HSA-1234177|Reactome:R-HSA-1234166|Reactome:R-HSA-1234181|Reactome:R-HSA-1234165|Reactome:R-HSA-1234173									molecular_function											owl:Class	
GO:0031543	biolink:NamedThing	peptidyl-proline dioxygenase activity	Catalysis of the reaction: peptidyl L-proline + 2-oxoglutarate + O2 = peptidyl hydroxy-L-proline + succinate + CO2.	tmpzr1t_l9r_go_relaxed.owl	prolyl hydroxylase activity|proline hydroxylase activity|proline,2-oxoglutarate 4-dioxygenase activity|prolyl 4-hydroxylase activity													molecular_function											owl:Class	
GO:0075118	biolink:NamedThing	modulation by symbiont of host G protein-coupled receptor signal transduction	Any process in which the symbiont modulates the frequency, rate or extent of the host G protein-coupled receptor signal transduction. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	modulation by symbiont of host signal transduction mediated by G-protein gamma subunit|modulation by symbiont of host signal transduction mediated by G-protein beta subunit|modulation by symbiont of host G-protein coupled receptor protein signal transduction|modulation by symbiont of host signal transduction mediated by G-protein alpha subunit					Note that this term is used to annotate gene products of the symbiont. To annotate host gene products, consider the biological process term "modulation by host of symbiont G protein-coupled receptor  signal transduction ; GO:0075087".						GO:0075124|GO:0075121|GO:0075127		biological_process											owl:Class	
GO:0075112	biolink:NamedThing	modulation by symbiont of host transmembrane receptor-mediated signal transduction	Any process in which the symbiont modulates the frequency, rate or extent of transmembrane receptor-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl						Note that this term is used to annotate gene products of the symbiont. To annotate host gene products, consider the biological process term "modulation by host of symbiont transmembrane receptor-mediated signal transduction ; GO:0075081".								biological_process											owl:Class	
GO:0006209	biolink:NamedThing	cytosine catabolic process	The chemical reactions and pathways resulting in the breakdown of cytosine, 4-amino-2-hydroxypyrimidine, a pyrimidine derivative that is one of the five main bases found in nucleic acids; it occurs widely in cytidine derivatives.	tmpzr1t_l9r_go_relaxed.owl	cytosine breakdown|cytosine catabolism|cytosine degradation													biological_process											owl:Class	
GO:0051583	biolink:NamedThing	dopamine uptake involved in synaptic transmission	The directed movement of dopamine into a presynaptic neuron or glial cell. In this context, dopamine is a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline.	tmpzr1t_l9r_go_relaxed.owl	dopamine import involved in synaptic transmission|dopamine reuptake involved in synaptic transmission													biological_process											owl:Class	
GO:0090494	biolink:NamedThing	dopamine uptake	The directed movement of dopamine into a cell.	tmpzr1t_l9r_go_relaxed.owl								tb	2012-10-17T11:12:09Z					biological_process											owl:Class	
GO:0019745	biolink:NamedThing	pentacyclic triterpenoid biosynthetic process	The chemical reactions and pathways resulting in the formation of pentacyclic triterpenoid compounds, terpenoids with six isoprene units and 5 carbon rings.	tmpzr1t_l9r_go_relaxed.owl	pentacyclic triterpenoid biosynthesis|pentacyclic triterpenoid anabolism|pentacyclic triterpenoid formation|pentacyclic triterpenoid synthesis													biological_process											owl:Class	
GO:0010828	biolink:NamedThing	positive regulation of glucose transmembrane transport	Any process that increases the frequency, rate or extent of glucose transport across a membrane. Glucose transport is the directed movement of the hexose monosaccharide glucose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of glucose transport													biological_process											owl:Class	
GO:0010827	biolink:NamedThing	regulation of glucose transmembrane transport	Any process that modulates the frequency, rate or extent of glucose transport across a membrane. Glucose transport is the directed movement of the hexose monosaccharide glucose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	regulation of glucose transport													biological_process											owl:Class	
GO:1902529	biolink:NamedThing	negative regulation of protein linear polyubiquitination	Any process that stops, prevents or reduces the frequency, rate or extent of protein linear polyubiquitination.	tmpzr1t_l9r_go_relaxed.owl	downregulation of M1 linkage|negative regulation of M1 linkage|down regulation of M1 linkage|down-regulation of M1 linkage|inhibition of protein linear polyubiquitination|inhibition of M1 linkage|down regulation of protein linear polyubiquitination|down-regulation of protein linear polyubiquitination|downregulation of protein linear polyubiquitination							ppm	2013-12-02T10:03:09Z					biological_process											owl:Class	
GO:1902528	biolink:NamedThing	regulation of protein linear polyubiquitination	Any process that modulates the frequency, rate or extent of protein linear polyubiquitination.	tmpzr1t_l9r_go_relaxed.owl	regulation of M1 linkage							ppm	2013-12-02T10:03:00Z					biological_process											owl:Class	
GO:0015420	biolink:NamedThing	ABC-type vitamin B12 transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: vitamin B12(out) + ATP + H2O = ADP + an vitamin B12(in) + H+ + phosphate. Vitamin B12 is alkylcob(III)alamin.	tmpzr1t_l9r_go_relaxed.owl	vitamin B12 porter activity|vitamin B12-transporting ATPase activity|ATPase-coupled vitamin B12 transmembrane transporter activity|ATP-dependent cobalamin transmembrane transporter activity|cobalamin-transporting ATPase activity|ATP-dependent vitamin B12 transmembrane transporter activity|ATPase-coupled cobalamin transmembrane transporter activity|cobalamin porter activity|vitamin B12 ABC transporter activity|cobalamin ABC transporter|cobalamin transporter activity|vitamin B12 transporter activity	https://github.com/geneontology/go-ontology/issues/21353			Reactome:R-HSA-3095901|Reactome:R-HSA-3000238|MetaCyc:ABC-5-RXN|RHEA:17873|Reactome:R-HSA-3315437|EC:7.6.2.8|MetaCyc:3.6.3.33-RXN							GO:0102023|GO:0015235		molecular_function											owl:Class	
GO:0070911	biolink:NamedThing	global genome nucleotide-excision repair	The nucleotide-excision repair process in which DNA lesions are removed from nontranscribed strands and from transcriptionally silent regions over the entire genome.	tmpzr1t_l9r_go_relaxed.owl	global genome NER|GG-NER|global genomic repair|global genomic nucleotide-excision repair|GGR							mah	2009-09-09T03:13:11Z					biological_process											owl:Class	
GO:1900934	biolink:NamedThing	positive regulation of nonadec-1-ene metabolic process	Any process that activates or increases the frequency, rate or extent of nonadec-1-ene metabolic process.	tmpzr1t_l9r_go_relaxed.owl	activation of nonadec-1-ene metabolic process|upregulation of nonadec-1-ene metabolic process|activation of nonadec-1-ene metabolism|positive regulation of nonadec-1-ene metabolism|up regulation of nonadec-1-ene metabolism|up-regulation of nonadec-1-ene metabolism|upregulation of nonadec-1-ene metabolism|up-regulation of nonadec-1-ene metabolic process|up regulation of nonadec-1-ene metabolic process							tt	2012-06-14T03:11:58Z					biological_process											owl:Class	
GO:0097691	biolink:NamedThing	bacterial extracellular vesicle	Small membrane vesicle (< 1 um) that buds off a prokaryotic cell plasma membrane, able to carry proteins, phospholipids, lipopolysaccharides, nucleic acids, viruses, and more. Important in intercellular communication and pathogenesis; can exist within host cells.	tmpzr1t_l9r_go_relaxed.owl								pr	2015-09-24T11:31:44Z					cellular_component											owl:Class	
GO:0030140	biolink:NamedThing	trans-Golgi network transport vesicle	A vesicle that mediates transport between the trans-Golgi network and other parts of the cell.	tmpzr1t_l9r_go_relaxed.owl	trans-Golgi network constitutive secretory pathway transport vesicle|TGN transport vesicle													cellular_component											owl:Class	
GO:0021720	biolink:NamedThing	superior olivary nucleus formation	The process that gives rise to the superior olivary nucleus. This process pertains to the initial formation of a structure from unspecified parts. In mice, the superior olivary nucleus is a small cylindrical mass on the dorsal surface of the lateral part of the trapezoid body of the pons, and it is situated immediately above the inferior olivary nucleus. It receives projections from the cochlear nucleus and thus is involved in the perception of sound.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0051593	biolink:NamedThing	response to folic acid	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a folic acid stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to folate|cellular response to vitamin B9													biological_process											owl:Class	
GO:0035970	biolink:NamedThing	peptidyl-threonine dephosphorylation	The removal of phosphoric residues from peptidyl-O-phospho-L-threonine to form peptidyl-threonine.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-08-08T02:57:11Z					biological_process											owl:Class	
GO:0099631	biolink:NamedThing	postsynaptic endocytic zone cytoplasmic component	The cytoplasmic component of the postsynaptic endocytic zone.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0099738	biolink:NamedThing	cell cortex region	The complete extent of cell cortex that underlies some some region of the plasma membrane.	tmpzr1t_l9r_go_relaxed.owl	perimembrane region													cellular_component											owl:Class	
GO:0120166	biolink:NamedThing	protoperithecium formation	The process of producing fruiting body precursors, called protoperithecia. Protoperitheicium is a spherical structure that is formed in the sexual phase of ascomycetous fungi such as Neurospora crassa and Sordaria macrospora. Protoperithecium is formed by the enveloping of ascogonia cells by sterile hyphae and it develops into perithecium.	tmpzr1t_l9r_go_relaxed.owl						Note that this term represents protoperithecium formation across homothallic and heterothallic species that do not have the same mechanism.		krc	2018-05-17T17:27:16Z					biological_process											owl:Class	
GO:0030582	biolink:NamedThing	reproductive fruiting body development	The process whose specific outcome is the progression of a reproductive fruiting body over time, from its formation to the mature structure. A reproductive fruiting body is a multicellular reproductive structure that contains spores.	tmpzr1t_l9r_go_relaxed.owl	fruiting body formation					This term describes the development of a fruiting body that is a spore-bearing organ.  It is not intended to describe the development of myxococcal fruiting bodies.								biological_process											owl:Class	
GO:1901925	biolink:NamedThing	negative regulation of protein import into nucleus during spindle assembly checkpoint	Any process that stops, prevents, or reduces the frequency, rate or extent of the movement of proteins from the cytoplasm into the nucleus, and that occurs as a response to the mitotic cell cycle spindle assembly checkpoint. In S. cerevisiae, this process involves inhibition of the karyopherin/importin Kap121p (also known as Pse1p), which acts as the specific nuclear import receptor for several proteins, including Glc7p. Glc7p functions in opposition to key spindle assembly checkpoint protein Aurora kinase (Ipl1p).	tmpzr1t_l9r_go_relaxed.owl	KTIP|negative regulation of protein import into nucleus during mitotic cell cycle spindle assembly checkpoint|Kap121p transport inhibitory pathway							pr	2013-02-17T20:55:16Z					biological_process											owl:Class	
GO:0072479	biolink:NamedThing	response to mitotic cell cycle spindle assembly checkpoint signaling	A process that occurs in response to signals generated as a result of mitotic cell cycle spindle assembly checkpoint signaling.	tmpzr1t_l9r_go_relaxed.owl	response to Dma1-dependent checkpoint signaling|mitotic cell cycle spindle assembly checkpoint effector process|response to signal involved in mitotic cell cycle spindle assembly checkpoint|response to Dma1-dependent checkpoint signalling							mah	2010-12-09T12:11:31Z			GO:0044811		biological_process											owl:Class	
GO:0051238	biolink:NamedThing	sequestering of metal ion	The process of binding or confining metal ions such that they are separated from other components of a biological system.	tmpzr1t_l9r_go_relaxed.owl	metal ion sequestering|metal ion retention|retention of metal ion|metal ion sequestration|metal ion storage|storage of metal ion|sequestration of metal ion													biological_process											owl:Class	
GO:0051235	biolink:NamedThing	maintenance of location	Any process in which a cell, substance or cellular entity, such as a protein complex or organelle, is maintained in a location and prevented from moving elsewhere.	tmpzr1t_l9r_go_relaxed.owl	maintenance of localization|retention|sequestering|storage													biological_process											owl:Class	
GO:0006026	biolink:NamedThing	aminoglycan catabolic process	The chemical reactions and pathways resulting in the breakdown of aminoglycans, any polymer containing amino groups that consists of more than about 10 monosaccharide residues joined to each other by glycosidic linkages.	tmpzr1t_l9r_go_relaxed.owl	aminoglycan degradation|aminoglycan catabolism|aminoglycan breakdown													biological_process											owl:Class	
GO:0009682	biolink:NamedThing	induced systemic resistance	A response to non-pathogenic bacteria that confers broad spectrum systemic resistance to disease that does not depend upon salicylic acid signaling.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0075184	biolink:NamedThing	regulation of infection cushion formation	Any process that modulates the frequency, rate or extent of symbiont infection cushion formation.	tmpzr1t_l9r_go_relaxed.owl	regulation of infection cushion formation on or near host													biological_process											owl:Class	
GO:0019661	biolink:NamedThing	glucose catabolic process to lactate via pyruvate	The anaerobic enzymatic chemical reactions and pathways resulting in the breakdown of glucose to lactate, via canonical glycolysis, yielding energy in the form of adenosine triphosphate (ATP).	tmpzr1t_l9r_go_relaxed.owl	homolactic fermentation|homofermentation|glucose fermentation to lactate via pyruvate|homofermentative lactate fermentation|homofermentative pathway|homolactate fermentation				MetaCyc:ANAEROFRUCAT-PWY									biological_process											owl:Class	
GO:0019660	biolink:NamedThing	glycolytic fermentation	Fermentation that includes the anaerobic conversion of glucose to pyruvate via the glycolytic pathway.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:Pyruvate-Degredation									biological_process											owl:Class	
GO:0034445	biolink:NamedThing	negative regulation of plasma lipoprotein oxidation	Any process that stops, prevents, or reduces the frequency, rate or extent of lipoprotein particle oxidation, occurring in the blood plasma.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of plasma lipoprotein particle oxidation|inhibition of plasma lipoprotein oxidation													biological_process											owl:Class	
GO:1990890	biolink:NamedThing	netrin receptor binding	Binding to a netrin receptor.	tmpzr1t_l9r_go_relaxed.owl								kmv	2015-11-02T22:56:07Z					molecular_function											owl:Class	
GO:0001809	biolink:NamedThing	positive regulation of type IV hypersensitivity	Any process that activates or increases the frequency, rate or extent of type IV hypersensitivity, a type of inflammatory response.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of type IV hypersensitivity|upregulation of type IV hypersensitivity|stimulation of type IV hypersensitivity|activation of type IV hypersensitivity|up regulation of type IV hypersensitivity													biological_process											owl:Class	
GO:0001807	biolink:NamedThing	regulation of type IV hypersensitivity	Any process that modulates the frequency, rate, or extent of type IV hypersensitivity, a type of inflammatory response.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0002356	biolink:NamedThing	peripheral B cell negative selection	Any process leading to negative selection of B cells in the periphery.	tmpzr1t_l9r_go_relaxed.owl	peripheral B-cell negative selection|peripheral B lymphocyte negative selection|peripheral B-lymphocyte negative selection													biological_process											owl:Class	
GO:0002343	biolink:NamedThing	peripheral B cell selection	Any B cell selection process that occurs in the periphery.	tmpzr1t_l9r_go_relaxed.owl	peripheral B lymphocyte selection|peripheral B-lymphocyte selection|peripheral B-cell selection													biological_process											owl:Class	
GO:0034718	biolink:NamedThing	SMN-Gemin2 complex	A protein complex that contains the survival motor neuron (SMN) protein and Gemin2; may form the stable core of the larger SMN complex.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0046149	biolink:NamedThing	pigment catabolic process	The chemical reactions and pathways resulting in the breakdown of a pigment, any general or particular coloring matter in living organisms, e.g. melanin.	tmpzr1t_l9r_go_relaxed.owl	pigment breakdown|pigment degradation|pigment catabolism													biological_process											owl:Class	
GO:0102909	biolink:NamedThing	alpha-ketoglutarate reductase activity (NADH-dependent)	Catalysis of the reaction: NAD + 2-hydroxyglutarate = H+ + 2-oxoglutarate + NADH.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-8645									molecular_function											owl:Class	
GO:0050420	biolink:NamedThing	maltose synthase activity	Catalysis of the reaction: 2 alpha-D-glucose 1-phosphate = maltose + 2 phosphate.	tmpzr1t_l9r_go_relaxed.owl	alpha-D-glucose-1-phosphate:alpha-D-glucose-1-phosphate 4-alpha-D-glucosyltransferase (dephosphorylating)				RHEA:22320|MetaCyc:MALTOSE-SYNTHASE-RXN|EC:2.4.1.139									molecular_function											owl:Class	
GO:0046566	biolink:NamedThing	DOPA dioxygenase activity	Catalysis of the 4,5-ring opening reaction: 3,4-dihydroxyphenylalanine + O2 = 4,5-seco-DOPA. 4,5-seco-DOPA spontaneously recyclizes to form betalamic acid.	tmpzr1t_l9r_go_relaxed.owl	dihydroxyphenylalanine dioxygenase activity				MetaCyc:RXN-8460									molecular_function											owl:Class	
GO:0046431	biolink:NamedThing	(R)-4-hydroxymandelate metabolic process	The chemical reactions and pathways involving (R)-4-hydroxymandelate, the anion of a hydroxylated derivative of mandelate (alpha-hydroxybenzeneacetate).	tmpzr1t_l9r_go_relaxed.owl	(R)-4-hydroxymandelate metabolism													biological_process											owl:Class	
GO:1900108	biolink:NamedThing	negative regulation of nodal signaling pathway	Any process that stops, prevents or reduces the frequency, rate or extent of nodal signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	downregulation of nodal signaling|negative regulation of nodal signalling pathway|down regulation of nodal signaling pathway|down-regulation of nodal signaling pathway|inhibition of nodal signaling pathway|inhibition of nodal signaling|down regulation of nodal signaling|down-regulation of nodal signaling|downregulation of nodal signaling pathway|negative regulation of nodal signaling							bf	2012-02-16T03:34:23Z					biological_process											owl:Class	
GO:0032926	biolink:NamedThing	negative regulation of activin receptor signaling pathway	Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of any activin receptor signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of activin receptor signaling pathway|negative regulation of activin signalling pathway|inhibition of activin receptor signaling pathway|downregulation of activin receptor signaling pathway|negative regulation of activin receptor signalling pathway|down regulation of activin receptor signaling pathway|negative regulation of activin signaling pathway													biological_process											owl:Class	
GO:0018652	biolink:NamedThing	toluene-sulfonate methyl-monooxygenase activity	Catalysis of the reaction: toluene-4-sulfonate + NADH + O2 = NAD+ + OH- + 4-sulfobenzyl alcohol.	tmpzr1t_l9r_go_relaxed.owl	toluene-sulphonate methyl-monooxygenase activity				RHEA:51024|UM-BBD_reactionID:r0290|MetaCyc:TSMOS-RXN									molecular_function											owl:Class	
GO:0031403	biolink:NamedThing	lithium ion binding	Binding to a lithium ion (Li+).	tmpzr1t_l9r_go_relaxed.owl	Li+ ion binding													molecular_function											owl:Class	
GO:0046983	biolink:NamedThing	protein dimerization activity	The formation of a protein dimer, a macromolecular structure consists of two noncovalently associated identical or nonidentical subunits.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0006045	biolink:NamedThing	N-acetylglucosamine biosynthetic process	The chemical reactions and pathways resulting in the formation of N-acetylglucosamine. The D isomer is a common structural unit of glycoproteins in plants, bacteria and animals; it is often the terminal sugar of an oligosaccharide group of a glycoprotein.	tmpzr1t_l9r_go_relaxed.owl	N-acetylglucosamine anabolism|N-acetylglucosamine synthesis|N-acetylglucosamine biosynthesis|N-acetylglucosamine formation													biological_process											owl:Class	
GO:1901073	biolink:NamedThing	glucosamine-containing compound biosynthetic process	The chemical reactions and pathways resulting in the formation of glucosamine-containing compounds (glucosamines).	tmpzr1t_l9r_go_relaxed.owl	glucosamines anabolism|glucosamines synthesis|glucosamine-containing compound synthesis|glucosamine-containing compound biosynthesis|glucosamines biosynthesis|glucosamine-containing compound formation|glucosamine-containing compound anabolism|glucosamines formation|glucosamines biosynthetic process							bf	2012-07-02T03:18:33Z					biological_process											owl:Class	
GO:0032721	biolink:NamedThing	negative regulation of lymphotoxin A production	Any process that stops, prevents, or reduces the frequency, rate, or extent of lymphotoxin A production.	tmpzr1t_l9r_go_relaxed.owl	downregulation of lymphotoxin A production|negative regulation of tumor necrosis factor-beta production|down regulation of lymphotoxin A production|negative regulation of lymphotoxin A biosynthetic process|negative regulation of lymphotoxin-alpha production|inhibition of lymphotoxin A production|negative regulation of TNF-beta production|down-regulation of lymphotoxin A production|negative regulation of LTA production											GO:0043018		biological_process											owl:Class	
GO:0031855	biolink:NamedThing	oxytocin receptor binding	Binding to an oxytocin receptor.	tmpzr1t_l9r_go_relaxed.owl	oxytocin receptor ligand													molecular_function											owl:Class	
GO:1900234	biolink:NamedThing	regulation of Kit signaling pathway	Any process that modulates the frequency, rate or extent of Kit signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	regulation of stem cell factor receptor signaling pathway|regulation of stem cell factor signaling pathway|regulation of Kit signalling pathway							bf	2012-03-23T02:54:13Z					biological_process											owl:Class	
GO:0009517	biolink:NamedThing	PSII associated light-harvesting complex II	Protein-pigment complex associated with photosystem II.	tmpzr1t_l9r_go_relaxed.owl	LHCII													cellular_component											owl:Class	
GO:0009503	biolink:NamedThing	thylakoid light-harvesting complex	A thylakoid membrane complex of chlorophylls a and b together with chlorophyll a-b binding proteins. In addition, LHCs contain a number of other proteins, the function of which is speculative, together with accessory pigments. The LHCs capture and transfer energy to photosystems I and II. An example of this is found in Arabidopsis thaliana.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0050604	biolink:NamedThing	taxadiene 5-alpha-hydroxylase activity	Catalysis of the reaction: AH(2) + O(2) + taxa-4,11-diene = A + H(2)O + taxa-4(20),11-dien-5alpha-ol.	tmpzr1t_l9r_go_relaxed.owl	taxadiene 5alpha-hydroxylase activity|taxadiene 5a-hydroxylase activity|taxa-4,11-diene,hydrogen-donor:oxygen oxidoreductase (5alpha-hydroxylating)				RHEA:14049|KEGG_REACTION:R06306|EC:1.14.14.176|MetaCyc:1.14.99.37-RXN									molecular_function											owl:Class	
GO:0033123	biolink:NamedThing	positive regulation of purine nucleotide catabolic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of purine nucleotides.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of purine nucleotide breakdown|positive regulation of purine nucleotide degradation|positive regulation of purine nucleotide catabolism													biological_process											owl:Class	
GO:1900544	biolink:NamedThing	positive regulation of purine nucleotide metabolic process	Any process that activates or increases the frequency, rate or extent of purine nucleotide metabolic process.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of purine metabolism|upregulation of purine metabolic process|activation of purine nucleotide metabolic process|upregulation of purine metabolism|up-regulation of purine metabolism|up regulation of purine metabolic process|positive regulation of purine metabolic process|up-regulation of purine nucleotide metabolic process|upregulation of purine nucleotide metabolism|positive regulation of purine nucleotide metabolism|activation of purine metabolism|up-regulation of purine nucleotide metabolism|upregulation of purine nucleotide metabolic process|up regulation of purine nucleotide metabolic process|up regulation of purine metabolism|activation of purine nucleotide metabolism|up regulation of purine nucleotide metabolism|activation of purine metabolic process|up-regulation of purine metabolic process							krc	2012-05-11T05:44:43Z					biological_process											owl:Class	
GO:0072267	biolink:NamedThing	metanephric capsule specification	The regionalization process in which the identity of the metanephric capsule is specified. Identity is considered to be the aggregate of characteristics by which a structure is recognized.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-03-30T02:57:36Z					biological_process											owl:Class	
GO:0072268	biolink:NamedThing	pattern specification involved in metanephros development	Any developmental process that results in the creation of defined areas or spaces within the metanephros to which cells respond and eventually are instructed to differentiate.	tmpzr1t_l9r_go_relaxed.owl	metanephros pattern formation|pattern formation involved in metanephros development|metanephros pattern specification							mah	2010-03-30T03:06:30Z					biological_process											owl:Class	
GO:1904153	biolink:NamedThing	negative regulation of retrograde protein transport, ER to cytosol	Any process that stops, prevents or reduces the frequency, rate or extent of retrograde protein transport, ER to cytosol.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of retrograde protein transport, endoplasmic reticulum to cytosol|down-regulation of protein dislocation from ER|downregulation of retrograde protein transport, endoplasmic reticulum to cytosol|negative regulation of protein dislocation from ER|downregulation of protein dislocation from ER|negative regulation of protein retrotranslocation from ER|negative regulation of retrograde protein transport, endoplasmic reticulum to cytosol|down regulation of retrograde protein transport, endoplasmic reticulum to cytosol|down regulation of protein dislocation from ER|inhibition of retrograde protein transport, ER to cytosol|downregulation of retrograde protein transport, ER to cytosol|down-regulation of retrograde protein transport, ER to cytosol|inhibition of protein dislocation from ER|inhibition of retrograde protein transport, endoplasmic reticulum to cytosol|down regulation of retrograde protein transport, ER to cytosol							bf	2015-04-15T09:23:13Z					biological_process											owl:Class	
GO:0050551	biolink:NamedThing	myrcene synthase activity	Catalysis of the reaction: geranyl diphosphate = diphosphate + myrcene.	tmpzr1t_l9r_go_relaxed.owl	geranyl-diphosphate diphosphate-lyase (myrcene-forming) activity				EC:4.2.3.15|RHEA:16965|MetaCyc:RXN-5110|KEGG_REACTION:R02009									molecular_function											owl:Class	
GO:0051543	biolink:NamedThing	regulation of elastin biosynthetic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of elastin.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0031488	biolink:NamedThing	myosin XVIII complex	A myosin complex containing a class XVIII myosin heavy chain and associated light chains; myosin XVIII heavy chains contain an N-terminal PDZ domain.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:1905433	biolink:NamedThing	negative regulation of retrograde trans-synaptic signaling by neuropeptide	Any process that stops, prevents or reduces the frequency, rate or extent of retrograde trans-synaptic signaling by neuropeptide.	tmpzr1t_l9r_go_relaxed.owl	inhibition of neuropeptide-mediated retrograde trans-synaptic signaling|inhibition of retrograde trans-synaptic signaling by neuropeptide|negative regulation of neuropeptide-mediated retrograde trans-synaptic signaling|downregulation of retrograde trans-synaptic signaling by neuropeptide|down-regulation of retrograde trans-synaptic signaling by neuropeptide|down regulation of retrograde trans-synaptic signaling by neuropeptide							bf	2016-09-14T10:56:55Z					biological_process											owl:Class	
GO:0046380	biolink:NamedThing	N-acetylneuraminate biosynthetic process	The chemical reactions and pathways resulting in the formation of N-acetylneuraminate, the anion of 5-(acetylamino)-3,5-dideoxy-D-glycero-D-galacto-non-3-ulosonic acid.	tmpzr1t_l9r_go_relaxed.owl	N-acetylneuraminate biosynthesis|N-acetylneuraminate anabolism|N-acetylneuraminate formation|N-acetylneuraminate synthesis													biological_process											owl:Class	
GO:1904825	biolink:NamedThing	protein localization to microtubule plus-end	A process in which a protein is transported to, or maintained in, a location at a microtubule plus-end.	tmpzr1t_l9r_go_relaxed.owl	protein localisation to microtubule plus-end							mah	2015-11-23T12:34:09Z					biological_process											owl:Class	
GO:0090317	biolink:NamedThing	negative regulation of intracellular protein transport	Any process that decreases the frequency, rate or extent of the directed movement of proteins within cells.	tmpzr1t_l9r_go_relaxed.owl								tb	2010-04-16T03:45:07Z					biological_process											owl:Class	
GO:0002018	biolink:NamedThing	renin-angiotensin regulation of aldosterone production	The process in which an increase in active angiotensin stimulates the adrenal cortices to secrete aldosterone.	tmpzr1t_l9r_go_relaxed.owl	renin-angiotensin control of aldosterone production													biological_process											owl:Class	
GO:2000445	biolink:NamedThing	positive regulation of toll-like receptor 21 signaling pathway	Any process that activates or increases the frequency, rate or extent of toll-like receptor 21 signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of TLR21 signaling pathway|positive regulation of toll-like receptor 21 signalling pathway							bf	2011-03-04T10:33:00Z					biological_process											owl:Class	
GO:1990404	biolink:NamedThing	protein ADP-ribosylase activity	The transfer, from NAD, of ADP-ribose to a protein amino acid residue.	tmpzr1t_l9r_go_relaxed.owl	ribosylase activity							pg	2014-06-24T07:04:44Z					molecular_function											owl:Class	
GO:1904514	biolink:NamedThing	positive regulation of initiation of premeiotic DNA replication	Any process that activates or increases the frequency, rate or extent of initiation of premeiotic DNA replication.	tmpzr1t_l9r_go_relaxed.owl	upregulation of meiotic DNA replication initiation|upregulation of initiation of meiotic DNA synthesis|up-regulation of meiotic DNA replication initiation|positive regulation of meiotic DNA replication initiation|positive regulation of initiation of meiotic DNA synthesis|upregulation of premeiotic DNA replication initiation|up regulation of premeiotic DNA replication initiation|up regulation of initiation of premeiotic DNA synthesis|up-regulation of premeiotic DNA replication initiation|activation of initiation of premeiotic DNA replication|up regulation of initiation of premeiotic DNA replication|activation of premeiotic DNA replication initiation|up regulation of initiation of meiotic DNA synthesis|activation of initiation of meiotic DNA synthesis|activation of meiotic DNA replication initiation|positive regulation of initiation of premeiotic DNA synthesis|upregulation of initiation of premeiotic DNA replication|up-regulation of initiation of meiotic DNA synthesis|up-regulation of initiation of premeiotic DNA synthesis|up regulation of meiotic DNA replication initiation|upregulation of initiation of premeiotic DNA synthesis|positive regulation of premeiotic DNA replication initiation|up-regulation of initiation of premeiotic DNA replication|activation of initiation of premeiotic DNA synthesis							mah	2015-07-28T12:59:29Z					biological_process											owl:Class	
GO:0098902	biolink:NamedThing	regulation of membrane depolarization during action potential	Any process that modulates the rate, frequency or extent of membrane depolarization during an action potential. Membrane depolarization is the process in which membrane potential changes in the depolarizing direction from the resting potential.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0071662	biolink:NamedThing	negative regulation of granzyme B production	Any process that stops, prevents, or reduces the frequency, rate, or extent of production of granzyme B.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-02-12T10:41:14Z					biological_process											owl:Class	
GO:0052832	biolink:NamedThing	inositol monophosphate 3-phosphatase activity	Catalysis of the reaction: myo-inositol 3-phosphate + H2O = myo-inositol + phosphate.	tmpzr1t_l9r_go_relaxed.owl					EC:3.1.3.25|Reactome:R-HSA-1855210|MetaCyc:MYO-INOSITOL-1OR-4-MONOPHOSPHATASE-RXN|RHEA:30739			ai	2011-11-29T11:00:09Z					molecular_function											owl:Class	
GO:0052834	biolink:NamedThing	inositol monophosphate phosphatase activity	Catalysis of the reaction: myo-inositol phosphate + H2O = myo-inositol + phosphate.	tmpzr1t_l9r_go_relaxed.owl	L-myo-inositol-phosphate phosphatase activity|inositol phosphatase activity|myo-inositol monophosphatase activity|myo-inositol-phosphate phosphohydrolase activity|inositol-phosphate phosphatase activity|myo-inositol-1(or 4)-phosphate phosphohydrolase activity|myo-inositol-phosphatase activity|myo-inositol phosphatase activity|inositol-1(or 4)-monophosphatase activity				RHEA:24056|MetaCyc:RXN-10949|EC:3.1.3.25			ai	2011-11-29T11:15:58Z					molecular_function											owl:Class	
GO:0102052	biolink:NamedThing	indole-3-acetyl-proline synthetase activity	Catalysis of the reaction: indole-3-acetate + L-proline + ATP(4-) <=> H+ + indole-3-acetyl-proline + AMP(2-) + diphosphoric acid.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-10434									molecular_function											owl:Class	
GO:0150145	biolink:NamedThing	positive regulation of CD80 production	Any process that activates or increases the frequency, rate or extent of CD80 biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of CD80 biosynthetic process							bc	2019-12-08T10:29:00Z					biological_process											owl:Class	
GO:0032733	biolink:NamedThing	positive regulation of interleukin-10 production	Any process that activates or increases the frequency, rate, or extent of interleukin-10 production.	tmpzr1t_l9r_go_relaxed.owl	up regulation of interleukin-10 production|activation of interleukin-10 production|upregulation of interleukin-10 production|positive regulation of interleukin-10 biosynthetic process|positive regulation of IL-10 production|up-regulation of interleukin-10 production|positive regulation of interleukin-10 secretion|stimulation of interleukin-10 production											GO:0045082|GO:2001181		biological_process											owl:Class	
GO:0015115	biolink:NamedThing	silicate transmembrane transporter activity	Enables the transfer of silicates from one side of a membrane to the other. Silicates are the salts of silicic acids, and are usually composed of silicon and oxygen (Si[x]O[y]), one or more metals, and possibly hydrogen. Types of silicate include unisilicates, metasilicates and hydrous silicates.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0004463	biolink:NamedThing	leukotriene-A4 hydrolase activity	Catalysis of the reaction: H(2)O + leukotriene A(4) = leukotriene B(4).	tmpzr1t_l9r_go_relaxed.owl	leukotriene A4 hydrolase activity|leukotriene A(4) hydrolase activity|LTA4 hydrolase activity|LTA-4 hydrolase activity|(7E,9E,11Z,14Z)-(5S,6S)-5,6-epoxyicosa-7,9,11,14-tetraenoate hydrolase activity|LTA4H				MetaCyc:LEUKOTRIENE-A4-HYDROLASE-RXN|KEGG_REACTION:R03057|RHEA:22324|Reactome:R-HSA-266072|EC:3.3.2.6									molecular_function											owl:Class	
GO:0150106	biolink:NamedThing	regulation of protein localization to cell-cell junction	Any process that modulates the frequency, rate or extent of protein localization to cell-cell junction.	tmpzr1t_l9r_go_relaxed.owl								bc	2019-06-11T11:17:15Z					biological_process											owl:Class	
GO:0099124	biolink:NamedThing	axonal dopamine secretion	The regulated release of dopamine from an axon.	tmpzr1t_l9r_go_relaxed.owl	axonal dopamine release|axonal DA release													biological_process											owl:Class	
GO:0014046	biolink:NamedThing	dopamine secretion	The regulated release of dopamine by a cell. Dopamine is a catecholamine and a precursor of adrenaline and noradrenaline. It acts as a neurotransmitter in the central nervous system but it is also produced peripherally and acts as a hormone.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1902656	biolink:NamedThing	calcium ion import into cytosol	The directed movement of calcium ion into a cytosol.	tmpzr1t_l9r_go_relaxed.owl	calcium import into cytosol							pr	2014-01-22T13:41:11Z					biological_process											owl:Class	
GO:0070509	biolink:NamedThing	calcium ion import	The directed movement of calcium ions into a cell or organelle.	tmpzr1t_l9r_go_relaxed.owl	transmembrane calcium influx|calcium ion uptake													biological_process											owl:Class	
GO:0120282	biolink:NamedThing	autolysosome lumen	The volume that is enclosed within the autolysosome single-membrane.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/20239						krc	2020-11-17T02:53:51Z					cellular_component											owl:Class	
GO:1903253	biolink:NamedThing	hercynylcysteine sulfoxide biosynthetic process	The chemical reactions and pathways resulting in the formation of hercynylcysteine sulfoxide.	tmpzr1t_l9r_go_relaxed.owl	hercynylcysteine sulfoxide anabolism|hercynylcysteine sulfoxide formation|hercynylcysteine sulfoxide synthesis|hercynylcysteine sulfoxide biosynthesis							mah	2014-08-06T09:14:00Z					biological_process											owl:Class	
GO:1903252	biolink:NamedThing	hercynylcysteine sulfoxide metabolic process	The chemical reactions and pathways involving hercynylcysteine sulfoxide.	tmpzr1t_l9r_go_relaxed.owl	hercynylcysteine sulfoxide metabolism							mah	2014-08-06T09:13:50Z					biological_process											owl:Class	
GO:0014865	biolink:NamedThing	detection of activity	The series of events in which an activity stimulus is received by a cell and converted into a molecular signal.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1904884	biolink:NamedThing	positive regulation of telomerase catalytic core complex assembly	Any process that activates or increases the frequency, rate or extent of telomerase catalytic core complex assembly.	tmpzr1t_l9r_go_relaxed.owl	activation of telomerase catalytic core complex assembly|positive regulation of TERT-TERC complex assembly|up-regulation of TERT-TERC complex assembly|positive regulation of TERT-TERC complex formation|activation of TERT-TERC complex assembly|upregulation of TERT-TERC complex formation|up regulation of telomerase catalytic core complex assembly|up regulation of telomerase catalytic core complex formation|up regulation of TERT-TERC complex assembly|upregulation of TERT-TERC complex assembly|positive regulation of telomerase catalytic core complex formation|activation of telomerase catalytic core complex formation|upregulation of telomerase catalytic core complex formation|upregulation of telomerase catalytic core complex assembly|up-regulation of telomerase catalytic core complex formation|up regulation of TERT-TERC complex formation|activation of TERT-TERC complex formation|up-regulation of TERT-TERC complex formation|up-regulation of telomerase catalytic core complex assembly							rph	2016-01-05T10:36:16Z					biological_process											owl:Class	
GO:0034845	biolink:NamedThing	naphthyl-2-methyl-succinyl-CoA dehydrogenase activity	Catalysis of the reaction: naphthyl-2-methyl-succinyl-CoA = naphthyl-2-methylene-succinyl-CoA + 2 H+ + 2 e-.	tmpzr1t_l9r_go_relaxed.owl					EC:1.3.99.-|UM-BBD_reactionID:r1258									molecular_function											owl:Class	
GO:0061112	biolink:NamedThing	negative regulation of bud outgrowth involved in lung branching	Any process that decreases the rate, frequency, or extent of bud outgrowth involved in lung branching.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-05-05T11:20:42Z					biological_process											owl:Class	
GO:0002370	biolink:NamedThing	natural killer cell cytokine production	Any process that contributes to cytokine production by a natural killer cell.	tmpzr1t_l9r_go_relaxed.owl	NK cell cytokine production					Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.								biological_process											owl:Class	
GO:2000874	biolink:NamedThing	regulation of glyoxylate cycle	Any process that modulates the frequency, rate or extent of glyoxylate cycle.	tmpzr1t_l9r_go_relaxed.owl	regulation of glyoxylate bypass							bf	2011-07-27T01:27:10Z					biological_process											owl:Class	
GO:1905834	biolink:NamedThing	response to pyrimidine ribonucleotide	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pyrimidine ribonucleotide stimulus.	tmpzr1t_l9r_go_relaxed.owl								sl	2017-01-17T19:23:59Z					biological_process											owl:Class	
GO:1905426	biolink:NamedThing	positive regulation of Wnt-mediated midbrain dopaminergic neuron differentiation	Any process that activates or increases the frequency, rate or extent of Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of frizzled signalling pathway involved in midbrain dopaminergic neuron differentiation|positive regulation of Wnt receptor signalling pathway involved in midbrain dopaminergic neuron differentiation|up-regulation of Wnt-activated signaling pathway involved in mDA neuron differentiation|positive regulation of frizzled signaling pathway involved in DA neurogenesis from midbrain floor plate|upregulation of Wingless signaling pathway involved in DA neurogenesis from midbrain floor plate|activation of Wingless signaling pathway involved in midbrain dopaminergic neuron differentiation|activation of Wingless signalling pathway involved in mDA neuron differentiation|activation of Wnt receptor signalling pathway involved in midbrain dopaminergic neuron differentiation|up-regulation of Wingless signaling pathway involved in mDA neuron differentiation|upregulation of Wnt-activated signaling pathway involved in DA neurogenesis from midbrain floor plate|upregulation of Wnt signaling pathway involved in midbrain DA neurogenesis|up-regulation of Wnt-activated signaling pathway involved in DA neurogenesis from midbrain floor plate|upregulation of frizzled signaling pathway involved in DA neurogenesis from midbrain floor plate|up-regulation of Wnt receptor signalling pathway involved in midbrain DA neurogenesis|positive regulation of Wingless signalling pathway involved in DA neurogenesis from midbrain floor plate|activation of Wg signalling pathway involved in midbrain DA neurogenesis|upregulation of Wnt receptor signaling pathway involved in midbrain dopaminergic neuron differentiation|up regulation of frizzled signaling pathway involved in midbrain DA neurogenesis|up regulation of Wnt receptor signaling pathway involved in DA neurogenesis from midbrain floor plate|up regulation of Wg signalling pathway involved in midbrain dopaminergic neuron differentiation|up-regulation of Wingless signalling pathway involved in midbrain dopaminergic neuron differentiation|positive regulation of Wnt receptor signaling pathway involved in midbrain dopaminergic neuron differentiation|up-regulation of Wingless signalling pathway involved in DA neurogenesis from midbrain floor plate|positive regulation of Wg signaling pathway involved in midbrain dopaminergic neuron production|up-regulation of Wingless signaling pathway involved in midbrain dopaminergic neuron differentiation|up regulation of Wnt-activated signaling pathway involved in midbrain dopaminergic neuron production|up-regulation of frizzled signaling pathway involved in midbrain dopaminergic neuron production|upregulation of frizzled signalling pathway involved in midbrain dopaminergic neuron differentiation|up-regulation of Wnt receptor signaling pathway involved in midbrain dopaminergic neuron production|activation of Wnt receptor signalling pathway involved in midbrain dopaminergic neuron production|up regulation of Wnt signaling pathway involved in midbrain dopaminergic neuron production|up regulation of Wnt receptor signalling pathway involved in midbrain DA neurogenesis|upregulation of Wnt signaling pathway involved in mDA neuron differentiation|upregulation of Wg signalling pathway involved in DA neurogenesis from midbrain floor plate|upregulation of Wg signalling pathway involved in midbrain dopaminergic neuron production|positive regulation of Wnt receptor signaling pathway involved in midbrain DA neurogenesis|positive regulation of frizzled signalling pathway involved in DA neurogenesis from midbrain floor plate|upregulation of Wnt-mediated midbrain DA neuron differentiation|up regulation of Wingless signalling pathway involved in midbrain dopaminergic neuron differentiation|positive regulation of Wg signaling pathway involved in mDA neuron differentiation|positive regulation of Wnt signaling pathway involved in mDA neuron differentiation|activation of Wnt receptor signaling pathway involved in midbrain dopaminergic neuron differentiation|up regulation of frizzled signalling pathway involved in DA neurogenesis from midbrain floor plate|up regulation of Wnt-activated signaling pathway involved in mDA neuron differentiation|up regulation of Wingless signalling pathway involved in midbrain DA neurogenesis|up regulation of Wnt receptor signalling pathway involved in midbrain dopaminergic neuron production|up-regulation of Wingless signalling pathway involved in mDA neuron differentiation|activation of Wg signalling pathway involved in midbrain dopaminergic neuron production|upregulation of frizzled signalling pathway involved in midbrain dopaminergic neuron production|up-regulation of Wg signalling pathway involved in DA neurogenesis from midbrain floor plate|upregulation of Wnt receptor signalling pathway involved in midbrain dopaminergic neuron differentiation|up regulation of Wg signalling pathway involved in midbrain DA neurogenesis|positive regulation of Wnt-activated signaling pathway involved in midbrain DA neurogenesis|activation of frizzled signalling pathway involved in midbrain DA neurogenesis|activation of Wnt receptor signaling pathway involved in midbrain dopaminergic neuron production|upregulation of Wnt-activated signaling pathway involved in midbrain dopaminergic neuron production|activation of Wingless signalling pathway involved in midbrain dopaminergic neuron differentiation|positive regulation of Wg signaling pathway involved in DA neurogenesis from midbrain floor plate|upregulation of frizzled signaling pathway involved in mDA neuron differentiation|up-regulation of Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation|upregulation of frizzled signaling pathway involved in midbrain dopaminergic neuron differentiation|upregulation of Wnt signaling pathway involved in midbrain dopaminergic neuron production|up-regulation of Wg signalling pathway involved in midbrain dopaminergic neuron differentiation|positive regulation of Wnt-activated signaling pathway involved in DA neurogenesis from midbrain floor plate|up regulation of Wingless signalling pathway involved in mDA neuron differentiation|up-regulation of Wg signalling pathway involved in midbrain DA neurogenesis|activation of Wnt-activated signaling pathway involved in mDA neuron differentiation|activation of Wingless signalling pathway involved in midbrain dopaminergic neuron production|up regulation of Wingless signaling pathway involved in midbrain dopaminergic neuron differentiation|activation of Wnt signaling pathway involved in midbrain dopaminergic neuron production|positive regulation of Wnt receptor signaling pathway involved in midbrain dopaminergic neuron production|up-regulation of Wingless signaling pathway involved in midbrain DA neurogenesis|upregulation of Wnt receptor signaling pathway involved in midbrain dopaminergic neuron production|activation of Wg signaling pathway involved in midbrain DA neurogenesis|up-regulation of Wnt-activated signaling pathway involved in midbrain dopaminergic neuron differentiation|up regulation of Wingless signaling pathway involved in midbrain DA neurogenesis|positive regulation of Wnt receptor signaling pathway involved in DA neurogenesis from midbrain floor plate|positive regulation of Wg signaling pathway involved in midbrain DA neurogenesis|up-regulation of Wg signaling pathway involved in midbrain dopaminergic neuron production|positive regulation of Wingless signalling pathway involved in mDA neuron differentiation|positive regulation of Wnt-activated signaling pathway involved in midbrain dopaminergic neuron differentiation|upregulation of Wg signaling pathway involved in midbrain dopaminergic neuron differentiation|activation of Wg signalling pathway involved in midbrain dopaminergic neuron differentiation|activation of Wnt receptor signaling pathway involved in DA neurogenesis from midbrain floor plate|activation of frizzled signaling pathway involved in mDA neuron differentiation|up-regulation of Wg signaling pathway involved in DA neurogenesis from midbrain floor plate|activation of Wg signaling pathway involved in DA neurogenesis from midbrain floor plate|upregulation of Wnt receptor signaling pathway involved in mDA neuron differentiation|upregulation of Wnt-activated signaling pathway involved in midbrain dopaminergic neuron differentiation|positive regulation of frizzled signalling pathway involved in midbrain dopaminergic neuron production|up regulation of Wg signaling pathway involved in midbrain DA neurogenesis|up regulation of Wingless signaling pathway involved in mDA neuron differentiation|upregulation of Wingless signalling pathway involved in midbrain dopaminergic neuron production|up regulation of Wingless signalling pathway involved in DA neurogenesis from midbrain floor plate|upregulation of Wnt receptor signaling pathway involved in DA neurogenesis from midbrain floor plate|upregulation of Wnt-activated signaling pathway involved in midbrain DA neurogenesis|up-regulation of Wnt receptor signaling pathway involved in mDA neuron differentiation|up-regulation of frizzled signaling pathway involved in DA neurogenesis from midbrain floor plate|up regulation of Wg signalling pathway involved in DA neurogenesis from midbrain floor plate|activation of Wnt-activated signaling pathway involved in midbrain dopaminergic neuron differentiation|positive regulation of midbrain dopaminergic neuron differentiation by positive regulation of Wnt signaling|activation of frizzled signalling pathway involved in mDA neuron differentiation|activation of Wnt-activated signaling pathway involved in midbrain dopaminergic neuron production|up regulation of Wg signaling pathway involved in midbrain dopaminergic neuron production|up regulation of frizzled signalling pathway involved in midbrain DA neurogenesis|up regulation of frizzled signaling pathway involved in mDA neuron differentiation|upregulation of Wnt receptor signalling pathway involved in mDA neuron differentiation|up regulation of Wingless signalling pathway involved in midbrain dopaminergic neuron production|up-regulation of frizzled signaling pathway involved in midbrain dopaminergic neuron differentiation|upregulation of Wnt-activated signaling pathway involved in mDA neuron differentiation|upregulation of Wg signalling pathway involved in midbrain dopaminergic neuron differentiation|positive regulation of Wg signalling pathway involved in midbrain dopaminergic neuron differentiation|upregulation of Wingless signaling pathway involved in midbrain DA neurogenesis|up-regulation of frizzled signalling pathway involved in mDA neuron differentiation|up regulation of frizzled signaling pathway involved in midbrain dopaminergic neuron production|activation of Wg signaling pathway involved in midbrain dopaminergic neuron production|up regulation of Wnt-activated signaling pathway involved in midbrain dopaminergic neuron differentiation|up-regulation of Wnt signaling pathway involved in midbrain dopaminergic neuron production|up regulation of Wnt-activated signaling pathway involved in midbrain DA neurogenesis|activation of Wnt receptor signaling pathway involved in midbrain DA neurogenesis|activation of Wg signalling pathway involved in mDA neuron differentiation|upregulation of Wg signaling pathway involved in mDA neuron differentiation|up-regulation of Wnt receptor signaling pathway involved in midbrain dopaminergic neuron differentiation|upregulation of frizzled signaling pathway involved in midbrain DA neurogenesis|up-regulation of Wnt receptor signalling pathway involved in mDA neuron differentiation|up-regulation of Wnt-mediated midbrain DA neuron differentiation|up regulation of Wnt receptor signaling pathway involved in midbrain dopaminergic neuron differentiation|up-regulation of Wg signaling pathway involved in mDA neuron differentiation|positive regulation of frizzled signaling pathway involved in mDA neuron differentiation|up-regulation of frizzled signalling pathway involved in midbrain dopaminergic neuron production|up-regulation of Wingless signalling pathway involved in midbrain DA neurogenesis|activation of Wingless signaling pathway involved in midbrain dopaminergic neuron production|activation of Wingless signaling pathway involved in midbrain DA neurogenesis|upregulation of Wnt signaling pathway involved in DA neurogenesis from midbrain floor plate|up regulation of Wingless signaling pathway involved in DA neurogenesis from midbrain floor plate|up regulation of Wnt-mediated midbrain DA neuron differentiation|up regulation of Wnt receptor signalling pathway involved in mDA neuron differentiation|activation of Wnt receptor signaling pathway involved in mDA neuron differentiation|upregulation of Wnt receptor signaling pathway involved in midbrain DA neurogenesis|up-regulation of Wg signalling pathway involved in mDA neuron differentiation|up regulation of Wingless signaling pathway involved in midbrain dopaminergic neuron production|positive regulation of Wnt signaling pathway involved in midbrain dopaminergic neuron production|positive regulation of Wnt receptor signalling pathway involved in midbrain DA neurogenesis|upregulation of Wingless signalling pathway involved in midbrain dopaminergic neuron differentiation|up-regulation of frizzled signaling pathway involved in mDA neuron differentiation|positive regulation of frizzled signalling pathway involved in mDA neuron differentiation|activation of Wg signalling pathway involved in DA neurogenesis from midbrain floor plate|activation of frizzled signalling pathway involved in midbrain dopaminergic neuron production|up regulation of Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation|up regulation of Wnt receptor signaling pathway involved in mDA neuron differentiation|upregulation of Wg signalling pathway involved in mDA neuron differentiation|up-regulation of Wnt receptor signaling pathway involved in midbrain DA neurogenesis|up regulation of frizzled signalling pathway involved in midbrain dopaminergic neuron differentiation|positive regulation of Wnt receptor signalling pathway involved in mDA neuron differentiation|positive regulation of Wg signalling pathway involved in DA neurogenesis from midbrain floor plate|activation of Wnt signaling pathway involved in DA neurogenesis from midbrain floor plate|up-regulation of Wnt receptor signalling pathway involved in DA neurogenesis from midbrain floor plate|positive regulation of Wingless signalling pathway involved in midbrain dopaminergic neuron differentiation|activation of Wnt signaling pathway involved in midbrain DA neurogenesis|up-regulation of Wnt signaling pathway involved in mDA neuron differentiation|upregulation of Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation|up-regulation of Wg signaling pathway involved in midbrain dopaminergic neuron differentiation|positive regulation of frizzled signaling pathway involved in midbrain dopaminergic neuron differentiation|upregulation of Wg signaling pathway involved in midbrain dopaminergic neuron production|positive regulation of Wnt receptor signaling pathway involved in mDA neuron differentiation|activation of frizzled signaling pathway involved in DA neurogenesis from midbrain floor plate|up regulation of Wnt-activated signaling pathway involved in DA neurogenesis from midbrain floor plate|up regulation of Wnt receptor signaling pathway involved in midbrain DA neurogenesis|upregulation of Wnt receptor signalling pathway involved in midbrain DA neurogenesis|activation of frizzled signalling pathway involved in DA neurogenesis from midbrain floor plate|up-regulation of Wg signaling pathway involved in midbrain DA neurogenesis|activation of Wg signaling pathway involved in midbrain dopaminergic neuron differentiation|upregulation of Wnt receptor signalling pathway involved in DA neurogenesis from midbrain floor plate|up-regulation of Wingless signalling pathway involved in midbrain dopaminergic neuron production|up regulation of Wnt signaling pathway involved in midbrain DA neurogenesis|positive regulation of Wg signalling pathway involved in mDA neuron differentiation|positive regulation of Wnt receptor signalling pathway involved in midbrain dopaminergic neuron production|upregulation of Wingless signalling pathway involved in DA neurogenesis from midbrain floor plate|activation of frizzled signaling pathway involved in midbrain DA neurogenesis|positive regulation of Wnt-mediated midbrain DA neuron differentiation|up regulation of Wg signaling pathway involved in mDA neuron differentiation|up regulation of Wg signalling pathway involved in mDA neuron differentiation|upregulation of frizzled signalling pathway involved in DA neurogenesis from midbrain floor plate|up regulation of frizzled signalling pathway involved in mDA neuron differentiation|activation of frizzled signaling pathway involved in midbrain dopaminergic neuron production|positive regulation of Wg signaling pathway involved in midbrain dopaminergic neuron differentiation|up regulation of Wnt receptor signalling pathway involved in DA neurogenesis from midbrain floor plate|up-regulation of Wnt receptor signaling pathway involved in DA neurogenesis from midbrain floor plate|activation of Wnt-mediated midbrain DA neuron differentiation|upregulation of Wingless signaling pathway involved in mDA neuron differentiation|up-regulation of Wnt receptor signalling pathway involved in midbrain dopaminergic neuron production|positive regulation of Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation|positive regulation of Wingless signaling pathway involved in midbrain dopaminergic neuron differentiation|positive regulation of Wnt-activated signaling pathway involved in mDA neuron differentiation|upregulation of frizzled signalling pathway involved in mDA neuron differentiation|activation of frizzled signalling pathway involved in midbrain dopaminergic neuron differentiation|up regulation of frizzled signaling pathway involved in midbrain dopaminergic neuron differentiation|activation of Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation|positive regulation of frizzled signalling pathway involved in midbrain DA neurogenesis|positive regulation of Wnt signaling pathway involved in DA neurogenesis from midbrain floor plate|up-regulation of Wnt receptor signalling pathway involved in midbrain dopaminergic neuron differentiation|positive regulation of Wg signalling pathway involved in midbrain DA neurogenesis|positive regulation of Wnt-activated signaling pathway involved in midbrain dopaminergic neuron production|activation of Wingless signaling pathway involved in mDA neuron differentiation|up-regulation of Wingless signaling pathway involved in midbrain dopaminergic neuron production|up-regulation of frizzled signalling pathway involved in midbrain DA neurogenesis|positive regulation of frizzled signaling pathway involved in midbrain dopaminergic neuron production|activation of Wnt-activated signaling pathway involved in DA neurogenesis from midbrain floor plate|up-regulation of Wnt signaling pathway involved in DA neurogenesis from midbrain floor plate|up regulation of Wnt receptor signalling pathway involved in midbrain dopaminergic neuron differentiation|upregulation of Wg signaling pathway involved in DA neurogenesis from midbrain floor plate|activation of Wingless signalling pathway involved in DA neurogenesis from midbrain floor plate|activation of Wnt receptor signalling pathway involved in midbrain DA neurogenesis|positive regulation of Wingless signaling pathway involved in midbrain dopaminergic neuron production|up-regulation of Wnt-activated signaling pathway involved in midbrain dopaminergic neuron production|positive regulation of Wingless signalling pathway involved in midbrain DA neurogenesis|upregulation of Wg signalling pathway involved in midbrain DA neurogenesis|up-regulation of Wg signalling pathway involved in midbrain dopaminergic neuron production|activation of Wnt-activated signaling pathway involved in midbrain DA neurogenesis|up-regulation of frizzled signaling pathway involved in midbrain DA neurogenesis|up-regulation of Wnt signaling pathway involved in midbrain DA neurogenesis|positive regulation of Wingless signalling pathway involved in midbrain dopaminergic neuron production|up-regulation of Wnt-activated signaling pathway involved in midbrain DA neurogenesis|upregulation of frizzled signaling pathway involved in midbrain dopaminergic neuron production|upregulation of Wg signaling pathway involved in midbrain DA neurogenesis|activation of Wingless signalling pathway involved in midbrain DA neurogenesis|activation of Wnt signaling pathway involved in mDA neuron differentiation|up regulation of Wg signalling pathway involved in midbrain dopaminergic neuron production|up-regulation of frizzled signalling pathway involved in DA neurogenesis from midbrain floor plate|up regulation of Wnt signaling pathway involved in DA neurogenesis from midbrain floor plate|upregulation of Wingless signaling pathway involved in midbrain dopaminergic neuron production|up regulation of Wnt signaling pathway involved in mDA neuron differentiation|positive regulation of frizzled signaling pathway involved in midbrain DA neurogenesis|activation of Wnt receptor signalling pathway involved in mDA neuron differentiation|up regulation of frizzled signalling pathway involved in midbrain dopaminergic neuron production|up regulation of frizzled signaling pathway involved in DA neurogenesis from midbrain floor plate|up-regulation of Wingless signaling pathway involved in DA neurogenesis from midbrain floor plate|positive regulation of Wingless signaling pathway involved in mDA neuron differentiation|activation of Wingless signaling pathway involved in DA neurogenesis from midbrain floor plate|activation of frizzled signaling pathway involved in midbrain dopaminergic neuron differentiation|up regulation of Wg signaling pathway involved in DA neurogenesis from midbrain floor plate|up regulation of Wg signaling pathway involved in midbrain dopaminergic neuron differentiation|activation of Wnt receptor signalling pathway involved in DA neurogenesis from midbrain floor plate|positive regulation of Wnt receptor signalling pathway involved in DA neurogenesis from midbrain floor plate|upregulation of frizzled signalling pathway involved in midbrain DA neurogenesis|upregulation of Wingless signalling pathway involved in midbrain DA neurogenesis|positive regulation of Wnt signaling pathway involved in midbrain DA neurogenesis|activation of Wg signaling pathway involved in mDA neuron differentiation|upregulation of Wingless signalling pathway involved in mDA neuron differentiation|upregulation of Wingless signaling pathway involved in midbrain dopaminergic neuron differentiation|positive regulation of Wingless signaling pathway involved in midbrain DA neurogenesis|upregulation of Wnt receptor signalling pathway involved in midbrain dopaminergic neuron production|positive regulation of Wingless signaling pathway involved in DA neurogenesis from midbrain floor plate|up regulation of Wnt receptor signaling pathway involved in midbrain dopaminergic neuron production|positive regulation of Wg signalling pathway involved in midbrain dopaminergic neuron production|positive regulation of frizzled signalling pathway involved in midbrain dopaminergic neuron differentiation							bf	2016-09-07T10:03:51Z					biological_process											owl:Class	
GO:0022832	biolink:NamedThing	voltage-gated channel activity	Enables the transmembrane transfer of a solute by a channel whose open state is dependent on the voltage across the membrane in which it is embedded.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1905907	biolink:NamedThing	negative regulation of amyloid fibril formation	Any process that stops, prevents or reduces the frequency, rate or extent of amyloid fibril formation.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of amyloid structure formation|down-regulation of amyloid structure assembly|downregulation of amyloid structure formation|downregulation of amyloid structure assembly|down-regulation of amyloid fibril assembly|inhibition of amyloid structure formation|negative regulation of amyloid fibril assembly|down-regulation of amyloid fibril formation|inhibition of amyloid structure assembly|down regulation of amyloid structure assembly|down regulation of amyloid fibril assembly|down-regulation of amyloid structure formation|downregulation of amyloid fibril formation|inhibition of amyloid fibril assembly|down regulation of amyloid structure formation|inhibition of amyloid fibril formation|negative regulation of amyloid structure assembly|downregulation of amyloid fibril assembly|down regulation of amyloid fibril formation					Although deposition of amyloid fibrils is associated with diseases, e.g. Alzheimer's disease, amyloid formation is a normal process. Disease occurs when the balance between amyloid formation and clearance is disrupted (reviewed e.g. in PMID:29654159 and PMID:28937655). An example of a normal amyloid complex is composed of human RIP1 and RIP3 kinases  (PMID:22817896).		bc	2017-02-03T15:43:56Z					biological_process											owl:Class	
GO:0032649	biolink:NamedThing	regulation of interferon-gamma production	Any process that modulates the frequency, rate, or extent of interferon-gamma production. Interferon-gamma is also known as type II interferon.	tmpzr1t_l9r_go_relaxed.owl	regulation of type II interferon production|regulation of interferon-gamma biosynthetic process|regulation of interferon-gamma secretion											GO:0045072|GO:1902713		biological_process											owl:Class	
GO:0039652	biolink:NamedThing	induction by virus of host NF-kappaB cascade	Any process in which a virus starts, promotes, or enhances a host NF-kappaB cascade.	tmpzr1t_l9r_go_relaxed.owl	activation by virus of host NF-kappaB transcription factor activity|activation of host NF-kappa-B by virus				VZ:841			bf	2012-10-11T16:04:31Z					biological_process											owl:Class	
GO:0001971	biolink:NamedThing	negative regulation of activation of membrane attack complex	Any process that stops, prevents, or reduces the frequency, rate or extent of the activation of the membrane attack complex components of the complement cascade.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of MAC formation|downregulation of activation of membrane attack complex|negative regulation of activation of terminal complement complex|negative regulation of membrane attack complex assembly|negative regulation of activation of MAC|negative regulation of activation of the terminal complement cascade|negative regulation of membrane attack complex formation|negative regulation of MAC assembly|negative regulation of activation of TCC|inhibition of activation of membrane attack complex|down regulation of activation of membrane attack complex|down-regulation of activation of membrane attack complex													biological_process											owl:Class	
GO:0044301	biolink:NamedThing	climbing fiber	The axon of inferior olive neuron that projects to the cerebellar cortex, largely via the inferior cerebellar peduncle. They range in diameter from 1-3 um and are myelinated until they enter the granule cell layer. They give off collaterals to the deep cerebellar nuclei. They synapse extensively with the dendrites of Purkinje cells in the molecular layer, where each fiber branches repeatedly to climb along the Purkinje cell dendritic tree. Each Purkinje cell is innervated by only a single climbing fiber.	tmpzr1t_l9r_go_relaxed.owl	climbing fibre				NIF_Subcellular:nlx_subcell_20090203			jl	2010-02-05T11:20:56Z					cellular_component											owl:Class	
GO:1905047	biolink:NamedThing	mitotic spindle pole body organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a mitotic spindle pole body.	tmpzr1t_l9r_go_relaxed.owl								vw	2016-03-14T09:48:42Z					biological_process											owl:Class	
GO:0051300	biolink:NamedThing	spindle pole body organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the spindle pole body (SPB). The SPB is the microtubule organizing center in fungi, and is functionally homologous to the animal cell centrosome.	tmpzr1t_l9r_go_relaxed.owl	spindle pole body organisation|spindle pole body maturation|spindle pole body organization and biogenesis|SPB organization|SPB maturation											GO:0051426		biological_process											owl:Class	
GO:0071496	biolink:NamedThing	cellular response to external stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external stimulus.	tmpzr1t_l9r_go_relaxed.owl						Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.		mah	2009-12-18T02:36:52Z					biological_process											owl:Class	
GO:0120215	biolink:NamedThing	positive regulation of histidine biosynthetic process	Any process that activates or increases the frequency, rate or extent of histidine biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	upregulation of histidine anabolism|up regulation of histidine biosynthetic process|up-regulation of histidine anabolism|positive regulation of histidine formation|up regulation of histidine anabolism|up regulation of histidine formation|up-regulation of histidine synthesis|activation of histidine synthesis|activation of histidine anabolism|activation of histidine biosynthetic process|activation of histidine formation|up regulation of histidine synthesis|upregulation of histidine biosynthetic process|upregulation of histidine biosynthesis|up-regulation of histidine biosynthetic process|up-regulation of histidine biosynthesis|positive regulation of histidine anabolism|positive regulation of histidine biosynthesis|upregulation of histidine formation|positive regulation of histidine synthesis|activation of histidine biosynthesis|up regulation of histidine biosynthesis|upregulation of histidine synthesis|up-regulation of histidine formation							krc	2019-06-27T20:57:28Z					biological_process											owl:Class	
GO:0042998	biolink:NamedThing	positive regulation of Golgi to plasma membrane protein transport	Any process that activates or increases the frequency, rate or extent of the transport of proteins from the Golgi to the plasma membrane.	tmpzr1t_l9r_go_relaxed.owl	upregulation of Golgi to plasma membrane protein transport|stimulation of Golgi to plasma membrane protein transport|up regulation of Golgi to plasma membrane protein transport|activation of Golgi to plasma membrane protein transport|up-regulation of Golgi to plasma membrane protein transport													biological_process											owl:Class	
GO:0006680	biolink:NamedThing	glucosylceramide catabolic process	The chemical reactions and pathways resulting in the breakdown of glucosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of glucose by a ceramide group.	tmpzr1t_l9r_go_relaxed.owl	glucosylceramide degradation|glucosylceramide breakdown|glucosylceramide catabolism													biological_process											owl:Class	
GO:0051331	biolink:NamedThing	meiotic G2 phase	The cell cycle 'gap' phase which is the interval between the completion of DNA synthesis and the beginning of DNA segregation by meiosis.	tmpzr1t_l9r_go_relaxed.owl	G2 phase of meiotic cell cycle					Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).								biological_process											owl:Class	
GO:1902481	biolink:NamedThing	gamma-tubulin complex assembly	The aggregation, arrangement and bonding together of a set of components to form a gamma-tubulin complex.	tmpzr1t_l9r_go_relaxed.owl	gamma-tubulin complex formation							mah	2013-11-04T13:21:12Z					biological_process											owl:Class	
GO:1901931	biolink:NamedThing	alpha-copaene biosynthetic process	The chemical reactions and pathways resulting in the formation of alpha-copaene.	tmpzr1t_l9r_go_relaxed.owl	alpha-copaene formation|alpha-copaene synthesis|alpha-copaene anabolism|alpha-copaene biosynthesis							ms	2013-02-18T14:54:48Z					biological_process											owl:Class	
GO:1901929	biolink:NamedThing	alpha-copaene metabolic process	The chemical reactions and pathways involving alpha-copaene.	tmpzr1t_l9r_go_relaxed.owl	alpha-copaene metabolism							ms	2013-02-18T14:54:39Z					biological_process											owl:Class	
GO:1904883	biolink:NamedThing	negative regulation of telomerase catalytic core complex assembly	Any process that stops, prevents or reduces the frequency, rate or extent of telomerase catalytic core complex assembly.	tmpzr1t_l9r_go_relaxed.owl	down regulation of TERT-TERC complex formation|negative regulation of telomerase catalytic core complex formation|inhibition of telomerase catalytic core complex assembly|downregulation of telomerase catalytic core complex formation|down-regulation of TERT-TERC complex assembly|inhibition of telomerase catalytic core complex formation|down-regulation of telomerase catalytic core complex formation|down regulation of telomerase catalytic core complex formation|down-regulation of TERT-TERC complex formation|negative regulation of TERT-TERC complex formation|downregulation of TERT-TERC complex assembly|inhibition of TERT-TERC complex assembly|negative regulation of TERT-TERC complex assembly|down-regulation of telomerase catalytic core complex assembly|down regulation of telomerase catalytic core complex assembly|downregulation of TERT-TERC complex formation|inhibition of TERT-TERC complex formation|down regulation of TERT-TERC complex assembly|downregulation of telomerase catalytic core complex assembly							rph	2016-01-05T10:36:09Z					biological_process											owl:Class	
GO:1904882	biolink:NamedThing	regulation of telomerase catalytic core complex assembly	Any process that modulates the frequency, rate or extent of telomerase catalytic core complex assembly.	tmpzr1t_l9r_go_relaxed.owl	regulation of TERT-TERC complex assembly|regulation of TERT-TERC complex formation|regulation of telomerase catalytic core complex formation							rph	2016-01-05T10:36:01Z					biological_process											owl:Class	
GO:0016726	biolink:NamedThing	oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which a CH2 group acts as a hydrogen or electron donor and reduces NAD+ or NADP.	tmpzr1t_l9r_go_relaxed.owl					EC:1.17.1.-									molecular_function											owl:Class	
GO:0099158	biolink:NamedThing	regulation of recycling endosome localization within postsynapse	Any process that modulates the frequency, rate or extent of transport or maintenance of location of a postsynaptic recycling endosome within the postsynapse.	tmpzr1t_l9r_go_relaxed.owl								dos	2017-08-25T15:37:50Z					biological_process											owl:Class	
GO:0061938	biolink:NamedThing	protein localization to somatodendritic compartment	A process in which a protein is transported to or maintained in a location within the somatodendritic compartment.	tmpzr1t_l9r_go_relaxed.owl	somatodendritic protein localization							dph	2017-09-08T13:22:26Z					biological_process											owl:Class	
GO:0000919	biolink:NamedThing	cell plate assembly	The process of assembly, maturation, and growth of the cell plate to the cell periphery in cells that divide by cell plate formation; often involves deposition of cell wall material in and around the phragmoplast.	tmpzr1t_l9r_go_relaxed.owl	cell plate formation													biological_process											owl:Class	
GO:1903277	biolink:NamedThing	negative regulation of sodium ion export across plasma membrane	Any process that stops, prevents or reduces the frequency, rate or extent of sodium ion export across the plasma membrane.	tmpzr1t_l9r_go_relaxed.owl	down regulation of sodium export|down-regulation of sodium export|negative regulation of sodium ion export from cell|downregulation of sodium export|downregulation of sodium ion export|down-regulation of sodium ion export from cell|negative regulation of sodium ion export|down-regulation of sodium ion export|inhibition of sodium ion export from cell|down regulation of sodium ion export|negative regulation of sodium export|inhibition of sodium ion export|inhibition of sodium export|down regulation of sodium ion export from cell|downregulation of sodium ion export from cell							rl	2014-08-08T17:10:22Z			GO:1903274		biological_process											owl:Class	
GO:1902306	biolink:NamedThing	negative regulation of sodium ion transmembrane transport	Any process that stops, prevents or reduces the frequency, rate or extent of sodium ion transmembrane transport.	tmpzr1t_l9r_go_relaxed.owl	down regulation of sodium ion membrane transport|downregulation of sodium ion membrane transport|down regulation of sodium ion transmembrane transport|downregulation of sodium ion transmembrane transport|inhibition of sodium ion membrane transport|negative regulation of sodium ion membrane transport|down-regulation of sodium ion transmembrane transport|down-regulation of sodium ion membrane transport|inhibition of sodium ion transmembrane transport							rl	2013-07-18T13:34:01Z					biological_process											owl:Class	
GO:1902242	biolink:NamedThing	copal-8-ol diphosphate(3-) catabolic process	The chemical reactions and pathways resulting in the breakdown of copal-8-ol diphosphate(3-).	tmpzr1t_l9r_go_relaxed.owl	copal-8-ol diphosphate(3-) degradation|copal-8-ol diphosphate(3-) catabolism|copal-8-ol diphosphate(3-) breakdown							ms	2013-06-20T09:09:33Z					biological_process											owl:Class	
GO:1902241	biolink:NamedThing	copal-8-ol diphosphate(3-) metabolic process	The chemical reactions and pathways involving copal-8-ol diphosphate(3-).	tmpzr1t_l9r_go_relaxed.owl	copal-8-ol diphosphate(3-) metabolism							ms	2013-06-20T09:09:27Z					biological_process											owl:Class	
GO:0032253	biolink:NamedThing	dense core granule localization	Any process in which a dense core granule is transported to, and/or maintained in, a specific location within the cell.	tmpzr1t_l9r_go_relaxed.owl	dense core vesicle localization|dense core granule localisation|dense core granule clustering													biological_process											owl:Class	
GO:0051941	biolink:NamedThing	regulation of amino acid uptake involved in synaptic transmission	Any process that modulates the frequency, rate or extent of the directed movement of amino acid neurotransmitters into a neuron or glial cell.	tmpzr1t_l9r_go_relaxed.owl	regulation of amino acid neurotransmitter reuptake|regulation of amino acid neurotransmitter uptake|regulation of amino acid uptake during transmission of nerve impulse													biological_process											owl:Class	
GO:0060346	biolink:NamedThing	bone trabecula formation	The process of creating a trabecula in the bone. A trabecula is a tissue element in the form of a small beam, strut or rod.	tmpzr1t_l9r_go_relaxed.owl	bone trabeculation|skeletal trabecula biogenesis|bone trabecula biogenesis|skeletal trabecula formation|skeletal trabeculation													biological_process											owl:Class	
GO:0071250	biolink:NamedThing	cellular response to nitrite	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrite stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-12-03T03:03:49Z					biological_process											owl:Class	
GO:1905008	biolink:NamedThing	regulation of L-lysine import across plasma membrane	Any process that modulates the frequency, rate or extent of L-lysine import into cell.	tmpzr1t_l9r_go_relaxed.owl	regulation of lysine import|regulation of lysine uptake|regulation of L-lysine import into cell							sl	2016-03-02T00:15:49Z			GO:0010805		biological_process											owl:Class	
GO:0051887	biolink:NamedThing	regulation of timing of exogen	Any process that modulates the frequency, rate or extent of timing of exogen, the shedding phase of the hair cycle.	tmpzr1t_l9r_go_relaxed.owl	regulation of exogen													biological_process											owl:Class	
GO:0035351	biolink:NamedThing	heme transmembrane transport	The process in which heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring, is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	heme membrane transport					Note that this term is not intended for use in annotating lateral movement within membranes.		bf	2010-03-04T03:45:46Z					biological_process											owl:Class	
GO:0018708	biolink:NamedThing	thiol S-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + a thiol = S-adenosyl-L-homocysteine + a thioether.	tmpzr1t_l9r_go_relaxed.owl	thiol methyltransferase activity|TMT|S-adenosyl-L-methionine:thiol S-methyltransferase activity				UM-BBD_enzymeID:e0146|Reactome:R-HSA-175976|RHEA:18277|EC:2.1.1.9|MetaCyc:THIOL-S-METHYLTRANSFERASE-RXN									molecular_function											owl:Class	
GO:0016480	biolink:NamedThing	negative regulation of transcription by RNA polymerase III	Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase III.	tmpzr1t_l9r_go_relaxed.owl	inhibition of transcription from RNA polymerase III promoter|down-regulation of transcription from RNA polymerase III promoter|down regulation of transcription from RNA polymerase III promoter|negative regulation of transcription from RNA polymerase III promoter|negative regulation of transcription from Pol III promoter|downregulation of transcription from RNA polymerase III promoter													biological_process											owl:Class	
GO:0034367	biolink:NamedThing	protein-containing complex remodeling	The acquisition, loss, or modification of macromolecules within a complex, resulting in the alteration of an existing complex.	tmpzr1t_l9r_go_relaxed.owl	macromolecular complex remodeling													biological_process											owl:Class	
GO:0061931	biolink:NamedThing	positive regulation of erythrocyte enucleation	Any process that increases the frequency, rate or extent of erythrocyte enucleation.	tmpzr1t_l9r_go_relaxed.owl								dph	2017-09-05T12:57:33Z					biological_process											owl:Class	
GO:0072022	biolink:NamedThing	descending thin limb development	The process whose specific outcome is the progression of the descending thin limb over time, from its formation to the mature structure. The descending thin limb is a part of the loop of Henle situated just after the proximal straight tubule (S3). It extends to the tip of the loop of Henle.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-01-25T02:37:47Z					biological_process											owl:Class	
GO:0006226	biolink:NamedThing	dUMP biosynthetic process	The chemical reactions and pathways resulting in the formation of dUMP, deoxyuridine monophosphate (2'-deoxyuridine 5'-phosphate).	tmpzr1t_l9r_go_relaxed.owl	dUMP anabolism|dUMP formation|dUMP biosynthesis|dUMP synthesis													biological_process											owl:Class	
GO:0008364	biolink:NamedThing	pupal chitin-based cuticle development	Synthesis and deposition of a chitin-based pupal cuticle. At the end of the prepupal period the insect is covered by the pupal cuticle which continues to be elaborated into the pupal period. An example of this is found in Drosophila melanogaster.	tmpzr1t_l9r_go_relaxed.owl	pupal cuticle synthesis|pupal cuticle formation|pupal cuticle anabolism													biological_process											owl:Class	
GO:0042337	biolink:NamedThing	cuticle development involved in chitin-based cuticle molting cycle	The synthesis and deposition of a chitin-based non-cellular, hardened, or membranous secretion from an epithelial sheet, occurring as part of the molting cycle. An example of this is found in Drosophila melanogaster.	tmpzr1t_l9r_go_relaxed.owl	cuticle anabolism during molting|cuticle biosynthetic process during molting|cuticle synthesis during molting|cuticle formation during molting|chitin-based cuticle development during molting													biological_process											owl:Class	
GO:0018867	biolink:NamedThing	alpha-pinene metabolic process	The chemical reactions and pathways involving alpha-pinene, a monoterpene that may be a significant factor affecting bacterial activities in nature. It is a major component in tea-tree oils, and gives off a piney smelling odor.	tmpzr1t_l9r_go_relaxed.owl	alpha-pinene metabolism				UM-BBD_pathwayID:apn									biological_process											owl:Class	
GO:0033073	biolink:NamedThing	pinene metabolic process	The chemical reactions and pathways involving the monoterpenoid pinene; alpha-pinene is (1S,5S)-2,6,6-trimethylbicyclo[3.1.1]hept-2-ene, and beta-pinene is (1S,5S)-6,6-dimethyl-2-methylenebicyclo[3.1.1]heptane.	tmpzr1t_l9r_go_relaxed.owl	pinene metabolism													biological_process											owl:Class	
GO:0006664	biolink:NamedThing	glycolipid metabolic process	The chemical reactions and pathways involving glycolipids, a class of 1,2-di-O-acylglycerols joined at oxygen 3 by a glycosidic linkage to a carbohydrate part (usually a mono-, di- or tri-saccharide). Some substances classified as bacterial glycolipids have the sugar group acylated by one or more fatty acids and the glycerol group may be absent.	tmpzr1t_l9r_go_relaxed.owl	glycolipid metabolism													biological_process											owl:Class	
GO:0033876	biolink:NamedThing	glycochenodeoxycholate sulfotransferase activity	Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + glycochenodeoxycholate = adenosine 3',5'-diphosphate + glycochenodeoxycholate 7-sulfate + H(+).	tmpzr1t_l9r_go_relaxed.owl	BAST|3'-phosphoadenylyl-sulfate:glycochenodeoxycholate 7-sulfotransferase activity|bile acid:PAPS:sulfotransferase activity|bile acid:3'-phosphoadenosine-5'-phosphosulfate sulfotransferase activity				MetaCyc:2.8.2.34-RXN|EC:2.8.2.34|KEGG_REACTION:R07289|RHEA:17689									molecular_function											owl:Class	
GO:0045071	biolink:NamedThing	negative regulation of viral genome replication	Any process that stops, prevents, or reduces the frequency, rate or extent of viral genome replication.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of viral genome replication|downregulation of viral genome replication|down regulation of viral genome replication|inhibition of viral genome replication													biological_process											owl:Class	
GO:0034655	biolink:NamedThing	nucleobase-containing compound catabolic process	The chemical reactions and pathways resulting in the breakdown of nucleobases, nucleosides, nucleotides and nucleic acids.	tmpzr1t_l9r_go_relaxed.owl	nucleobase, nucleoside, nucleotide and nucleic acid catabolism|nucleobase, nucleoside, nucleotide and nucleic acid catabolic process|nucleobase, nucleoside, nucleotide and nucleic acid breakdown|nucleobase, nucleoside, nucleotide and nucleic acid degradation													biological_process											owl:Class	
GO:1903505	biolink:NamedThing	regulation of establishment of actomyosin contractile ring localization involved in mitotic cell cycle	Any process that modulates the frequency, rate or extent of establishment of actomyosin contractile ring localization involved in mitotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl								al	2014-10-01T13:59:19Z					biological_process											owl:Class	
GO:1902471	biolink:NamedThing	regulation of mitotic actomyosin contractile ring localization	Any process that modulates the frequency, rate or extent of mitotic actomyosin contractile ring localization.	tmpzr1t_l9r_go_relaxed.owl								mah	2013-10-24T14:20:03Z					biological_process											owl:Class	
GO:0080004	biolink:NamedThing	thalian-diol desaturase activity	Catalysis of the reaction: a thalian-diol = a desaturated thalian-diol. This reaction is the introduction of a double bond to a thalian-diol molecule at carbon 15.	tmpzr1t_l9r_go_relaxed.owl					EC:1.14.21.-|MetaCyc:RXN-9637									molecular_function											owl:Class	
GO:1901915	biolink:NamedThing	positive regulation of capsule organization	Any process that activates or increases the frequency, rate or extent of capsule organization.	tmpzr1t_l9r_go_relaxed.owl	up regulation of capsule organization|positive regulation of capsule organization and biogenesis|activation of capsule organization|up regulation of capsule organization and biogenesis|up regulation of capsule organisation|positive regulation of capsule organisation|activation of capsule organisation|up-regulation of capsule organization and biogenesis|up-regulation of capsule organization|upregulation of capsule organisation|up-regulation of capsule organisation|upregulation of capsule organization|activation of capsule organization and biogenesis|upregulation of capsule organization and biogenesis							di	2013-02-14T06:19:16Z					biological_process											owl:Class	
GO:0044174	biolink:NamedThing	host cell endosome	A membrane-bounded organelle that carries materials newly ingested by endocytosis. It passes many of the materials to host cell lysosomes for degradation.	tmpzr1t_l9r_go_relaxed.owl	host endosome							jl	2009-09-04T03:02:01Z					cellular_component											owl:Class	
GO:0051561	biolink:NamedThing	positive regulation of mitochondrial calcium ion concentration	Any process that increases the concentration of calcium ions in mitochondria.	tmpzr1t_l9r_go_relaxed.owl	elevation of mitochondrial calcium ion concentration|mitochondrial calcium ion concentration elevation|elevation of calcium ion concentration in mitochondria|elevation of calcium ion concentration in mitochondrion													biological_process											owl:Class	
GO:0051560	biolink:NamedThing	mitochondrial calcium ion homeostasis	Any process involved in the maintenance of an internal steady state of calcium ions within the cytoplasm of a cell or between mitochondria and their surroundings.	tmpzr1t_l9r_go_relaxed.owl	calcium ion homeostasis in mitochondrion|calcium ion homeostasis in mitochondria|regulation of calcium ion concentration in mitochondrion|regulation of mitochondrial calcium ion concentration|regulation of calcium ion concentration in mitochondria|mitochondrial calcium ion concentration regulation													biological_process											owl:Class	
GO:0072327	biolink:NamedThing	vulval cell fate specification	The process in which a cell becomes capable of differentiating autonomously into a nematode vulval cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed. In nematodes, the vulva is formed from ventral epidermal cells during larval stages to give rise to a fully formed adult vulva, which is the egg-laying organ of female and hermaphrodite nematodes.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-11-01T02:14:06Z					biological_process											owl:Class	
GO:1903857	biolink:NamedThing	negative regulation of cytokinin dehydrogenase activity	Any process that stops, prevents or reduces the frequency, rate or extent of cytokinin dehydrogenase activity.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of N6-dimethylallyladenine:acceptor oxidoreductase activity|downregulation of 6-N-dimethylallyladenine:acceptor oxidoreductase activity|down regulation of cytokinin dehydrogenase activity|negative regulation of N6-dimethylallyladenine:(acceptor) oxidoreductase activity|down-regulation of N6-dimethylallyladenine:(acceptor) oxidoreductase activity|down-regulation of N6-dimethylallyladenine:acceptor oxidoreductase activity|inhibition of cytokinin oxidase activity|downregulation of cytokinin oxidase activity|down-regulation of cytokinin dehydrogenase activity|down regulation of cytokinin oxidase activity|negative regulation of cytokinin oxidase activity|down regulation of N6-dimethylallyladenine:acceptor oxidoreductase activity|downregulation of N6-dimethylallyladenine:(acceptor) oxidoreductase activity|downregulation of N6-dimethylallyladenine:acceptor oxidoreductase activity|down-regulation of cytokinin oxidase activity|down-regulation of 6-N-dimethylallyladenine:acceptor oxidoreductase activity|negative regulation of 6-N-dimethylallyladenine:acceptor oxidoreductase activity|inhibition of N6-dimethylallyladenine:(acceptor) oxidoreductase activity|inhibition of cytokinin dehydrogenase activity|inhibition of 6-N-dimethylallyladenine:acceptor oxidoreductase activity|inhibition of N6-dimethylallyladenine:acceptor oxidoreductase activity|downregulation of cytokinin dehydrogenase activity|down regulation of N6-dimethylallyladenine:(acceptor) oxidoreductase activity|down regulation of 6-N-dimethylallyladenine:acceptor oxidoreductase activity							tb	2015-01-30T00:34:01Z					biological_process											owl:Class	
GO:0090523	biolink:NamedThing	cytochrome-b5 reductase activity, acting on NADPH	Catalysis of the reaction: NADPH + H+ + 2 ferricytochrome b(5) = NADP+ + 2 ferrocytochrome b(5).	tmpzr1t_l9r_go_relaxed.owl	cytochrome-b5 reductase activity				RHEA:64576			tb	2013-01-11T12:21:41Z					molecular_function											owl:Class	
GO:0051732	biolink:NamedThing	polyribonucleotide kinase activity	Catalysis of the reaction: NTP + 5'-dephospho-RNA = NDP + 5'-phospho-RNA.	tmpzr1t_l9r_go_relaxed.owl	RNA kinase activity|5'-hydroxyl RNA kinase activity|RNA 5'-hydroxyl kinase activity|5'-hydroxyl polyribonucleotide kinase activity													molecular_function											owl:Class	
GO:0009324	biolink:NamedThing	D-amino-acid dehydrogenase complex	A protein complex that possesses D-amino-acid dehydrogenase activity.	tmpzr1t_l9r_go_relaxed.owl						See also the molecular function term 'D-amino-acid oxidase activity ; GO:0003884'.								cellular_component											owl:Class	
GO:0072209	biolink:NamedThing	metanephric mesangial cell differentiation	The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesangial cells of the metanephros as it progresses from its formation to the mature state.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-03-18T11:56:44Z					biological_process											owl:Class	
GO:0033172	biolink:NamedThing	gas vesicle shell	The proteinaceous structure surrounding a gas vesicle.	tmpzr1t_l9r_go_relaxed.owl	gas vesicle membrane|gas vesicle wall													cellular_component											owl:Class	
GO:0062139	biolink:NamedThing	camera-type eye photoreceptor cell development	The process whose specific outcome is the progression of a light-responsive receptor in a camera-type eye over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl								dph	2019-08-06T12:40:36Z					biological_process											owl:Class	
GO:0031321	biolink:NamedThing	ascospore-type prospore assembly	During ascospore formation, the process in which each haploid nucleus becomes encapsulated by a double membrane.	tmpzr1t_l9r_go_relaxed.owl	forespore formation|ascospore-type prospore formation													biological_process											owl:Class	
GO:0033917	biolink:NamedThing	exo-poly-alpha-galacturonosidase activity	Catalysis of the hydrolysis of pectic acid from the non-reducing end, releasing digalacturonate.	tmpzr1t_l9r_go_relaxed.owl	exopolygalacturonosidase activity|exopolygalacturanosidase activity				RHEA:56232|MetaCyc:3.2.1.82-RXN|EC:3.2.1.82									molecular_function											owl:Class	
GO:0052782	biolink:NamedThing	amino disaccharide catabolic process	The chemical reactions and pathways resulting in the breakdown of any amino disaccharide, a disaccharide having one or more substituted or unsubstituted amino groups in place of hydroxy groups at unspecified positions.	tmpzr1t_l9r_go_relaxed.owl								ai	2011-10-03T08:56:04Z					biological_process											owl:Class	
GO:0052779	biolink:NamedThing	amino disaccharide metabolic process	The chemical reactions and pathways involving any amino disaccharide, a disaccharide having one or more substituted or unsubstituted amino groups in place of hydroxy groups at unspecified positions.	tmpzr1t_l9r_go_relaxed.owl									2011-10-03T08:47:05Z					biological_process											owl:Class	
GO:0080006	biolink:NamedThing	internode patterning	Determines the spacing between two shoot nodes. A shoot node is the region of the shoot where the spikelet, flower, floret, branch, bud and/or leaves are attached.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0019867	biolink:NamedThing	outer membrane	The external membrane of Gram-negative bacteria or certain organelles such as mitochondria and chloroplasts; freely permeable to most ions and metabolites.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0001054	biolink:NamedThing	RNA polymerase I activity	Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template that contains an RNA polymerase I specific promoter to direct initiation and catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'.	tmpzr1t_l9r_go_relaxed.owl	DNA-directed RNA polymerase activity involved in transcription from RNA polymerase I promoter							krc	2010-09-23T03:36:11Z					molecular_function											owl:Class	
GO:0032672	biolink:NamedThing	regulation of interleukin-3 production	Any process that modulates the frequency, rate, or extent of interleukin-3 production.	tmpzr1t_l9r_go_relaxed.owl	regulation of interleukin-3 biosynthetic process|regulation of IL-3 production											GO:0045399		biological_process											owl:Class	
GO:0009329	biolink:NamedThing	acetate CoA-transferase complex	A heterotetrameric enzyme complex made up of two alpha subunits and two beta subunits. Part of the acetyl-CoA carboxylase complex. Catalyzes the transfer of a carboxyl group to form malonyl-CoA.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0032706	biolink:NamedThing	negative regulation of interleukin-22 production	Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-22 production.	tmpzr1t_l9r_go_relaxed.owl	down regulation of interleukin-22 production|negative regulation of IL-22 production|inhibition of interleukin-22 production|down-regulation of interleukin-22 production|downregulation of interleukin-22 production|negative regulation of interleukin-22 biosynthetic process											GO:0045394		biological_process											owl:Class	
GO:0042549	biolink:NamedThing	photosystem II stabilization	The stabilization of the photosystem II protein complex, resulting from the phosphorylation of its structural protein subunits, in a cell actively involved in photosynthesis.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0051886	biolink:NamedThing	negative regulation of timing of anagen	Any process that stops, prevents, or reduces the frequency, rate or extent of timing of anagen, the growth phase of the hair cycle.	tmpzr1t_l9r_go_relaxed.owl	down regulation of anagen|inhibition of anagen|downregulation of anagen|negative regulation of anagen|down-regulation of anagen													biological_process											owl:Class	
GO:0042376	biolink:NamedThing	phylloquinone catabolic process	The chemical reactions and pathways resulting in the breakdown of phylloquinone, vitamin K1, a quinone-derived compound synthesized by green plants.	tmpzr1t_l9r_go_relaxed.owl	phytylmenaquinone catabolism|phytomenadione catabolic process|phytonadione catabolic process|phylloquinone catabolism|phylloquinone breakdown|vitamin K1 catabolic process|phytylmenaquinone catabolic process|phytonadione catabolism|phylloquinone degradation|phytomenadione catabolism|vitamin K1 catabolism													biological_process											owl:Class	
GO:0042374	biolink:NamedThing	phylloquinone metabolic process	The chemical reactions and pathways involving phylloquinone, a quinone-derived compound synthesized by green plants. Phylloquinone has vitamin K activity and is known as vitamin K1.	tmpzr1t_l9r_go_relaxed.owl	phytonadione metabolism|phylloquinone metabolism|vitamin K1 metabolic process|phytylmenaquinone metabolism|phytonadione metabolic process|phytomenadione metabolism|phytomenadione metabolic process|vitamin K1 metabolism|phytylmenaquinone metabolic process													biological_process											owl:Class	
GO:2001093	biolink:NamedThing	galactotriose transport	The directed movement of a galactotrioseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl								jl	2011-09-21T02:01:29Z					biological_process											owl:Class	
GO:1901446	biolink:NamedThing	negative regulation of response to propan-1-ol	Any process that stops, prevents or reduces the frequency, rate or extent of response to propan-1-ol.	tmpzr1t_l9r_go_relaxed.owl	inhibition of response to propan-1-ol|downregulation of response to propan-1-ol|down regulation of response to propan-1-ol|down-regulation of response to propan-1-ol							tt	2012-10-02T14:13:52Z					biological_process											owl:Class	
GO:0015794	biolink:NamedThing	glycerol-3-phosphate transmembrane transport	The process in which glycerol-3-phosphate is transported across a membrane. Glycerol-3-phosphate is a phosphoric monoester of glycerol.	tmpzr1t_l9r_go_relaxed.owl	glycerol-3-phosphate transport													biological_process											owl:Class	
GO:1901900	biolink:NamedThing	regulation of protein localization to cell division site	Any process that modulates the frequency, rate or extent of protein localization to cell division site.	tmpzr1t_l9r_go_relaxed.owl	regulation of protein localisation to cell division site							dph	2013-02-11T12:27:55Z					biological_process											owl:Class	
GO:0000379	biolink:NamedThing	tRNA-type intron splice site recognition and cleavage	RNA processing that begins when the tertiary structure of a tRNA type intron is recognized, and ends when the endonucleolytic cleavage of the RNA at both the 5' and 3' splice sites occurs.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0071078	biolink:NamedThing	fibronectin-tissue transglutaminase complex	A protein complex that consists of fibronectin bound to tissue transglutaminase, and is involved in cell adhesion.	tmpzr1t_l9r_go_relaxed.owl	FN-TGM2 complex							mah	2009-11-06T04:42:22Z					cellular_component											owl:Class	
GO:0072686	biolink:NamedThing	mitotic spindle	A spindle that forms as part of mitosis. Mitotic and meiotic spindles contain distinctive complements of proteins associated with microtubules.	tmpzr1t_l9r_go_relaxed.owl								mah	2011-07-08T05:08:16Z					cellular_component											owl:Class	
GO:0045547	biolink:NamedThing	dehydrodolichyl diphosphate synthase activity	Catalysis of the condensation of isopentenyl diphosphate and farnesyl diphosphate in the cis-configuration to form dehydrodolichyl diphosphate.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0097094	biolink:NamedThing	craniofacial suture morphogenesis	The process in which any suture between cranial and/or facial bones is generated and organized.	tmpzr1t_l9r_go_relaxed.owl								pr	2011-07-05T02:51:54Z					biological_process											owl:Class	
GO:0019124	biolink:NamedThing	peptidyl-isoleucine racemization	The racemization of peptidyl-isoleucine.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0192							GO:0018370|GO:0018088		biological_process											owl:Class	
GO:0035249	biolink:NamedThing	synaptic transmission, glutamatergic	The vesicular release of glutamate from a presynapse, across a chemical synapse, the subsequent activation of glutamate receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse.	tmpzr1t_l9r_go_relaxed.owl	glutamatergic synaptic transmission													biological_process											owl:Class	
GO:0014863	biolink:NamedThing	detection of inactivity	The series of events in which a inactivity stimulus is received by a cell or organism and converted into a molecular signal.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0014854	biolink:NamedThing	response to inactivity	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an inactivity stimulus.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0098633	biolink:NamedThing	collagen fibril binding	Binding to a collagen fibril.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0033395	biolink:NamedThing	beta-alanine biosynthetic process via 3-hydroxypropionate	The chemical reactions and pathways resulting in the formation of beta-alanine via the intermediate 3-hydroxypropionate.	tmpzr1t_l9r_go_relaxed.owl	beta-alanine synthesis via 3-hydroxypropionate|beta-alanine anabolism via 3-hydroxypropionate|beta-alanine biosynthesis via 3-hydroxypropionate|beta-alanine formation via 3-hydroxypropionate				MetaCyc:PWY-3941									biological_process											owl:Class	
GO:1902260	biolink:NamedThing	negative regulation of delayed rectifier potassium channel activity	Any process that stops, prevents or reduces the frequency, rate or extent of delayed rectifier potassium channel activity.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of delayed rectifier potassium channel activity|downregulation of delayed rectifier potassium channel activity|down regulation of delayed rectifier potassium channel activity|inhibition of delayed rectifier potassium channel activity							rl	2013-06-25T12:16:24Z					biological_process											owl:Class	
GO:1905496	biolink:NamedThing	regulation of triplex DNA binding	Any process that modulates the frequency, rate or extent of triplex DNA binding.	tmpzr1t_l9r_go_relaxed.owl								ans	2016-09-26T14:57:09Z					biological_process											owl:Class	
GO:0009343	biolink:NamedThing	biotin carboxylase complex	An enzyme complex that catalyzes the formation of carboxybiotin-carboxyl-carrier protein from biotin-carboxyl-carrier protein and carbon dioxide (CO2).	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0033181	biolink:NamedThing	plasma membrane proton-transporting V-type ATPase complex	A proton-transporting two-sector ATPase complex found in the plasma membrane.	tmpzr1t_l9r_go_relaxed.owl	plasma membrane hydrogen ion-transporting ATPase													cellular_component											owl:Class	
GO:0033176	biolink:NamedThing	proton-transporting V-type ATPase complex	A proton-transporting two-sector ATPase complex that couples ATP hydrolysis to the transport of protons across a concentration gradient. The resulting transmembrane electrochemical potential of H+ is used to drive a variety of (i) secondary active transport systems via H+-dependent symporters and antiporters and (ii) channel-mediated transport systems. The complex comprises a membrane sector (V0) that carries out proton transport and a cytoplasmic compartment sector (V1) that catalyzes ATP hydrolysis. V-type ATPases are found in the membranes of organelles such as vacuoles, endosomes, and lysosomes, and in the plasma membrane.	tmpzr1t_l9r_go_relaxed.owl	hydrogen-translocating V-type ATPase complex													cellular_component											owl:Class	
GO:0080016	biolink:NamedThing	(-)-E-beta-caryophyllene synthase activity	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = (-)-E-beta-caryophyllene + diphosphate.	tmpzr1t_l9r_go_relaxed.owl					EC:4.2.3.57|MetaCyc:RXN-8414|RHEA:28294									molecular_function											owl:Class	
GO:0009350	biolink:NamedThing	ethanolamine ammonia-lyase complex	An enzyme complex that catalyzes the breakdown of ethanolamine to form acetaldehyde and ammonia.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0033708	biolink:NamedThing	isocitrate-homoisocitrate dehydrogenase activity	Catalysis of the reactions: isocitrate + NAD+ = 2-oxoglutarate + CO2 + NADH, and (1R,2S)-1-hydroxybutane-1,2,4-tricarboxylate + NAD+ = 2-oxoadipate + CO2 + NADH + H+.	tmpzr1t_l9r_go_relaxed.owl	PH1722|homoisocitrate-isocitrate dehydrogenase activity|isocitrate(homoisocitrate):NAD+ oxidoreductase (decarboxylating) activity				MetaCyc:RXN-7969|EC:1.1.1.286									molecular_function											owl:Class	
GO:2001230	biolink:NamedThing	positive regulation of response to gamma radiation	Any process that activates or increases the frequency, rate or extent of response to gamma radiation.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of response to gamma-ray photon|positive regulation of response to gamma ray							yaf	2011-11-20T04:51:17Z					biological_process											owl:Class	
GO:0030971	biolink:NamedThing	receptor tyrosine kinase binding	Binding to a receptor that possesses protein tyrosine kinase activity.	tmpzr1t_l9r_go_relaxed.owl	transmembrane receptor protein tyrosine kinase ligand binding													molecular_function											owl:Class	
GO:1990782	biolink:NamedThing	protein tyrosine kinase binding	Binding to protein tyrosine kinase.	tmpzr1t_l9r_go_relaxed.owl	tyrosine kinase binding							sl	2015-06-23T20:50:58Z					molecular_function											owl:Class	
GO:0140641	biolink:NamedThing	mitotic spindle formation (spindle phase two)	The spindle organization process in which the spindle is maintained at a constant length during mitotic metaphase.	tmpzr1t_l9r_go_relaxed.owl	metaphase spindle stabilization|metaphase spindle stability	https://github.com/geneontology/go-ontology/issues/21349						pg	2021-05-11T08:15:15Z					biological_process											owl:Class	
GO:0090307	biolink:NamedThing	mitotic spindle assembly	Mitotic bipolar spindle assembly begins with spindle microtubule nucleation from the separated spindle pole body, includes spindle elongation during prometaphase, and is complete when all kinetochores are stably attached the spindle, and the spindle assembly checkpoint is satisfied.	tmpzr1t_l9r_go_relaxed.owl	spindle assembly involved in mitosis							tb	2010-04-09T11:31:28Z					biological_process											owl:Class	
GO:0031415	biolink:NamedThing	NatA complex	A conserved complex that catalyzes the transfer of an acetyl group to an N-terminal Ser, Ala, Gly, or Thr residue of a protein acceptor molecule. In Saccharomyces the complex includes Nat1p and Ard1p, and may contain additional proteins.	tmpzr1t_l9r_go_relaxed.owl	N-terminal acetyltransferase A complex													cellular_component											owl:Class	
GO:1904360	biolink:NamedThing	negative regulation of spore germination	Any process that stops, prevents or reduces the frequency, rate or extent of spore germination.	tmpzr1t_l9r_go_relaxed.owl	inhibition of spore germination|downregulation of spore germination|down regulation of spore germination|down-regulation of spore germination|negative regulation of spore germination on or near host							pf	2015-06-12T19:46:12Z			GO:0075008		biological_process											owl:Class	
GO:1904359	biolink:NamedThing	regulation of spore germination	Any process that modulates the frequency, rate or extent of spore germination.	tmpzr1t_l9r_go_relaxed.owl	modulation of spore germination on or near host							pf	2015-06-12T19:46:06Z			GO:0075006		biological_process											owl:Class	
GO:0006064	biolink:NamedThing	glucuronate catabolic process	The chemical reactions and pathways resulting in the breakdown of glucuronate, any salt or ester of glucuronic acid.	tmpzr1t_l9r_go_relaxed.owl	glucuronate catabolism|glucuronate degradation|glucuronate breakdown													biological_process											owl:Class	
GO:0048227	biolink:NamedThing	plasma membrane to endosome transport	Transport of a vesicle from the plasma membrane to the endosome.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0018131	biolink:NamedThing	oxazole or thiazole biosynthetic process	The chemical reactions and pathways resulting in the formation of oxazole or thiazole, five-membered heterocyclic ring structures containing an oxygen and a sulfur, respectively, in the 1-position and a nitrogen in the 3-position.	tmpzr1t_l9r_go_relaxed.owl	oxazole or thiazole anabolism|oxazole or thiazole formation|oxazole or thiazole synthesis|oxazole or thiazole biosynthesis													biological_process											owl:Class	
GO:0009325	biolink:NamedThing	nitrate reductase complex	An enzyme complex that catalyzes the formation of nitrate from nitrite with the concomitant reduction of an acceptor.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0006668	biolink:NamedThing	sphinganine-1-phosphate metabolic process	The chemical reactions and pathways involving sphinganine-1-phosphate, the phosphorylated derivative of D-erythro-2-amino-1,3-octadecanediol.	tmpzr1t_l9r_go_relaxed.owl	dihydrosphingosine-1-phosphate metabolism|sphinganine-1-phosphate metabolism|dihydrosphingosine-1-phosphate metabolic process													biological_process											owl:Class	
GO:0060887	biolink:NamedThing	limb epidermis development	The process whose specific outcome is the progression of the epidermis of the limb over time, from its formation to the mature structure. The limb epidermis is the outer epithelial layer of the limb, it is a complex stratified squamous epithelium.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-08-13T12:39:39Z					biological_process											owl:Class	
GO:0047757	biolink:NamedThing	chondroitin-glucuronate 5-epimerase activity	Catalysis of the reaction: chondroitin D-glucuronate = dermatan L-iduronate.	tmpzr1t_l9r_go_relaxed.owl	chondroitin D-glucuronosyl 5-epimerase activity|dermatan-sulfate 5-epimerase activity|polyglucuronate 5-epimerase activity|chondroitin-D-glucuronate 5-epimerase activity|urunosyl C-5 epimerase activity				Reactome:R-HSA-2022052|MetaCyc:CHONDROITIN-GLUCURONATE-5-EPIMERASE-RXN|EC:5.1.3.19|RHEA:21084									molecular_function											owl:Class	
GO:0080185	biolink:NamedThing	effector-mediated induction of plant hypersensitive response by symbiont	A symbiont process in which a molecule secreted by the symbiont activates a resistance gene-dependent defense response signaling pathway in the plant host, in order to activate a hypersensitive response to induce necrosis. In the plant, this process involves the direct or indirect recognition of the symbiont effector protein for example through plant resistance receptor or R proteins (or R genes).	tmpzr1t_l9r_go_relaxed.owl	effector-triggered induction of host innate immune response|positive regulation by symbiont of plant HR|activation by symbiont of host resistance gene-dependent defense response|effector-triggered necrosis|ETI-triggered of host innate immune response|effector-triggered induction of plant hypersensitive response by symbiont|induction of effector-triggered immunity (ETI)|positive regulation by organism of host gene-for-gene resistance|induction by symbiont of host resistance gene-dependent defense response|avirulence protein|ETI triggered of host innate immune response|activation of HR|necrotrophic effector|induction by organism of defense response in host by specific elicitors|positive regulation by symbiont of host resistance gene-dependent defense response|induction by organism of resistance gene-dependent defense response of other organism involved in symbiotic interaction|positive regulation by organism of defense response in host by specific elicitors|induction by organism of host gene-for-gene resistance|activation by organism of host gene-for-gene resistance|induction by organism of pathogen-race/host plant cultivar-specific resistance in host|activation by organism of defense response in host by specific elicitors|positive regulation by symbiont of plant hypersensitive response|effector-triggered immunity|activation by organism of host resistance gene-dependent defense response|activation of hypersensitive response	https://github.com/geneontology/go-ontology/issues/18694			Wikipedia:Effector-triggered_immunity			dhl	2011-08-10T04:33:53Z			GO:0052527|GO:0052101|GO:0052423|GO:0052286		biological_process											owl:Class	
GO:0034053	biolink:NamedThing	modulation by symbiont of host defense-related programmed cell death	Any process in which a symbiont modulates the frequency, rate or extent of defense-related programmed cell death in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	modulation by symbiont of plant HR|modulation by symbiont of host HR|modulation by symbiont of plant hypersensitive response|modulation by symbiont of host hypersensitive response|modulation by symbiont of host defense-related PCD					Note that this term is used to annotate gene products of the symbiont. To annotate host gene products, consider the biological process term 'plant-type hypersensitive response ; GO:0009626'.								biological_process											owl:Class	
GO:0048397	biolink:NamedThing	positive regulation of intermediate mesodermal cell fate determination	Any process that activates or increases the frequency, rate or extent of intermediate mesoderm cell fate determination.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of intermediate mesodermal cell fate determination|upregulation of intermediate mesodermal cell fate determination|stimulation of intermediate mesodermal cell fate determination|up regulation of intermediate mesodermal cell fate determination|activation of intermediate mesodermal cell fate determination													biological_process											owl:Class	
GO:0048336	biolink:NamedThing	positive regulation of mesodermal cell fate determination	Any process that activates or increases the frequency, rate or extent of mesoderm cell fate determination.	tmpzr1t_l9r_go_relaxed.owl	up regulation of mesodermal cell fate determination|upregulation of mesodermal cell fate determination|activation of mesodermal cell fate determination|stimulation of mesodermal cell fate determination|up-regulation of mesodermal cell fate determination													biological_process											owl:Class	
GO:0070876	biolink:NamedThing	SOSS complex	A protein complex that functions downstream of the MRN complex to promote DNA repair and the G2/M checkpoint. The SOSS complex associates with single-stranded DNA at DNA lesions and is composed of SOSS-B (SOSS-B1/OBFC2B or SOSS-B2/OBFC2A), SOSS-A/INTS3 and SOSS-C/C9orf80.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-08-20T03:30:48Z					cellular_component											owl:Class	
GO:1902650	biolink:NamedThing	negative regulation of histone H2A-H2B dimer displacement	Any process that stops, prevents or reduces the frequency, rate or extent of histone H2A-H2B dimer displacement.	tmpzr1t_l9r_go_relaxed.owl	downregulation of histone H2A-H2B dimer displacement|inhibition of histone H2A-H2B dimer displacement|down-regulation of histone H2A-H2B dimer displacement|down regulation of histone H2A-H2B dimer displacement							di	2014-01-21T18:19:14Z					biological_process											owl:Class	
GO:1902649	biolink:NamedThing	regulation of histone H2A-H2B dimer displacement	Any process that modulates the frequency, rate or extent of histone H2A-H2B dimer displacement.	tmpzr1t_l9r_go_relaxed.owl								di	2014-01-21T18:19:04Z					biological_process											owl:Class	
GO:0072302	biolink:NamedThing	negative regulation of metanephric glomerular mesangial cell proliferation	Any process that decreases the frequency, rate or extent of metanephric glomerular mesangial cell proliferation.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-04-09T05:03:41Z					biological_process											owl:Class	
GO:0102125	biolink:NamedThing	gibberellin A9 16alpha,17 epoxidase activity	Catalysis of the reaction: gibberellin A9 + O2 + H+ + NAD(P)H <=> 16alpha, 17-epoxy gibberellin A9 + H2O + NAD(P).	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-11388									molecular_function											owl:Class	
GO:0060271	biolink:NamedThing	cilium assembly	The assembly of a cilium, a specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole.	tmpzr1t_l9r_go_relaxed.owl	microtubule-based flagellum assembly|ciliogenesis|cilium morphogenesis|cilium organization|cilium biogenesis|cilium formation				Reactome:R-HSA-5617833.2	Note that we deem cilium and microtubule-based flagellum to be equivalent.						GO:0042384		biological_process											owl:Class	
GO:0019311	biolink:NamedThing	sorbose metabolic process	The chemical reactions and pathways involving sorbose, the ketohexose xylo-2-hexulose. Sorbose is produced commercially by fermentation and is used as an intermediate in the manufacture of ascorbic acid.	tmpzr1t_l9r_go_relaxed.owl	sorbose metabolism													biological_process											owl:Class	
GO:0072020	biolink:NamedThing	proximal straight tubule development	The process whose specific outcome is the progression of the proximal straight tubule over time, from its formation to the mature structure. The proximal straight tubule is the part of the descending limb that extends from the proximal convoluted tubule to the descending thin tubule.	tmpzr1t_l9r_go_relaxed.owl	S3 development							mah	2010-01-25T02:36:14Z					biological_process											owl:Class	
GO:0102978	biolink:NamedThing	furaneol oxidoreductase activity	Catalysis of the reaction: 4-hydroxy-2,5-dimethylfuran-3-one + NADP <=> 4-hydroxy-5-methyl-2-methylenefuran-3-one + NADPH + H+.	tmpzr1t_l9r_go_relaxed.owl					RHEA:39111|MetaCyc:RXN-9563|EC:1.3.1.105									molecular_function											owl:Class	
GO:0010837	biolink:NamedThing	regulation of keratinocyte proliferation	Any process that modulates the rate, frequency or extent of keratinocyte proliferation. Keratinocyte proliferation is the multiplication or reproduction of keratinocytes, resulting in the expansion of a cell population.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0002384	biolink:NamedThing	hepatic immune response	An immune response taking place in the liver.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0002251	biolink:NamedThing	organ or tissue specific immune response	An immune response taking place in an organ or tissues such as the liver, brain, mucosa, or nervous system tissues.	tmpzr1t_l9r_go_relaxed.owl	immune response in organ or tissue													biological_process											owl:Class	
GO:0034826	biolink:NamedThing	1,2-dihydroxy-1,2,5,6,7,8-hexyhadronaphthalene dehydrogenase activity	Catalysis of the reaction: cis-1,2-dihydroxy-1,2,5,6,7,8-hexahydronaphthalene + NAD+ = 1,2-dihydroxy-5,6,7,8-tetrahydronaphthalene + NADH + H+.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r1170									molecular_function											owl:Class	
GO:0051884	biolink:NamedThing	regulation of timing of anagen	Any process that modulates the frequency, rate or extent of timing of anagen, the growth phase of the hair cycle.	tmpzr1t_l9r_go_relaxed.owl	regulation of anagen													biological_process											owl:Class	
GO:1903790	biolink:NamedThing	guanine nucleotide transmembrane transport	The process in which a guanyl nucleotide is transported across a membrane.	tmpzr1t_l9r_go_relaxed.owl	guanyl nucleotide transmembrane transport							dph	2015-01-10T13:51:54Z					biological_process											owl:Class	
GO:0009051	biolink:NamedThing	pentose-phosphate shunt, oxidative branch	The branch of the pentose-phosphate shunt which involves the oxidation of glucose 6-P and produces ribulose 5-P, reduced NADP+ and carbon dioxide (CO2).	tmpzr1t_l9r_go_relaxed.owl	pentose phosphate shunt, oxidative branch|oxidative pentose phosphate pathway|pentose phosphate pathway, oxidative branch|pentose-phosphate pathway, oxidative branch|oxidative branch, pentose pathway				MetaCyc:OXIDATIVEPENT-PWY									biological_process											owl:Class	
GO:2000858	biolink:NamedThing	regulation of aldosterone secretion	Any process that modulates the frequency, rate or extent of aldosterone secretion.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-07-26T08:47:27Z					biological_process											owl:Class	
GO:0016843	biolink:NamedThing	amine-lyase activity	Catalysis of the release of amines by the cleavage of a carbon-nitrogen bond or the reverse reaction with an amine as a substrate.	tmpzr1t_l9r_go_relaxed.owl					EC:4.3.3.-									molecular_function											owl:Class	
GO:0016840	biolink:NamedThing	carbon-nitrogen lyase activity	Catalysis of the release of ammonia or one of its derivatives, with the formation of a double bond or ring. Enzymes with this activity may catalyze the actual elimination of the ammonia, amine or amide, e.g. CH-CH(-NH-R) = C=CH- + NH2-R. Others, however, catalyze elimination of another component, e.g. water, which is followed by spontaneous reactions that lead to breakage of the C-N bond, e.g. L-serine ammonia-lyase (EC:4.3.1.17), so that the overall reaction is C(-OH)-CH(-NH2) = CH2-CO- + NH3, i.e. an elimination with rearrangement. The sub-subclasses of EC:4.3 are the ammonia-lyases (EC:4.3.1), lyases acting on amides, amidines, etc. (EC:4.3.2), the amine-lyases (EC:4.3.3), and other carbon-nitrogen lyases (EC:4.3.99).	tmpzr1t_l9r_go_relaxed.owl	other carbon-nitrogen lyase activity				EC:4.3.-.-									molecular_function											owl:Class	
GO:1904878	biolink:NamedThing	negative regulation of calcium ion transmembrane transport via high voltage-gated calcium channel	Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion transmembrane transport via high voltage-gated calcium channel.	tmpzr1t_l9r_go_relaxed.owl	downregulation of generation of L-type calcium current|down-regulation of generation of L-type calcium current|negative regulation of generation of L-type calcium current|down regulation of generation of L-type calcium current|inhibition of generation of L-type calcium current							sl	2015-12-18T22:30:37Z					biological_process											owl:Class	
GO:1903010	biolink:NamedThing	regulation of bone development	Any process that modulates the frequency, rate or extent of bone development.	tmpzr1t_l9r_go_relaxed.owl								mr	2014-05-13T22:41:53Z					biological_process											owl:Class	
GO:0016213	biolink:NamedThing	linoleoyl-CoA desaturase activity	Catalysis of the reaction: linoleoyl-CoA + reduced acceptor + O2 = gamma-linolenoyl-CoA + acceptor + 2 H2O.	tmpzr1t_l9r_go_relaxed.owl	delta6-acyl CoA desaturase activity|linoleate desaturase activity|delta(6)-fatty acyl-CoA desaturase activity|delta(6)-acyl CoA desaturase activity|linoleic acid desaturase activity|delta6-fatty acyl-CoA desaturase activity|long-chain fatty acid delta(6)-desaturase activity|linoleoyl-coenzyme A desaturase activity|fatty acid delta(6)-desaturase activity|delta(6)-desaturase activity|fatty acid 6-desaturase activity|long-chain fatty acid delta6-desaturase activity|delta6-desaturase activity|linoleic desaturase activity|fatty acid delta6-desaturase activity|linoleoyl CoA desaturase activity				Reactome:R-HSA-2046099|RHEA:47140|MetaCyc:1.14.19.3-RXN|Reactome:R-HSA-2046084|Reactome:R-HSA-2046096|EC:1.14.19.3|Reactome:R-HSA-2046097	Note that this function was formerly EC:1.14.99.25.								molecular_function											owl:Class	
GO:0030399	biolink:NamedThing	autophagosome membrane disassembly	The controlled breakdown of the membranes of autophagosomes.	tmpzr1t_l9r_go_relaxed.owl	autophagic membrane catabolism|autophagic membrane degradation|autophagic vacuole membrane disassembly|autophagic membrane breakdown													biological_process											owl:Class	
GO:0030775	biolink:NamedThing	glucuronoxylan 4-O-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + glucuronoxylan D-glucuronate = S-adenosyl-L-homocysteine + glucuronoxylan 4-O-methyl-D-glucuronate.	tmpzr1t_l9r_go_relaxed.owl	S-adenosyl-L-methionine:glucuronoxylan-D-glucuronate 4-O-methyltransferase activity				EC:2.1.1.112|RHEA:20413|MetaCyc:GLUCURONOXYLAN-4-O-METHYLTRANSFERASE-RXN									molecular_function											owl:Class	
GO:0075319	biolink:NamedThing	positive regulation of ascus development	Any process that activates, maintains or increases the frequency, rate or extent of ascus development, a saclike structure produced by fungi of the phylum Ascomycota (sac fungi) in which sexually produced spores (ascospores), usually four or eight in number, are formed.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0075318	biolink:NamedThing	regulation of ascus development	Any process that modulates the frequency, rate or extent of ascus development, a process that leads to the formation of basidium, a sac-like structure produced by fungi of the phylum Ascomycota (sac fungi) in which sexually produced spores (ascospores), usually four or eight in number, are formed.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0033098	biolink:NamedThing	amyloplast inner membrane	The inner, i.e. lumen-facing, lipid bilayer of the amyloplast envelope; also faces the amyloplast stroma.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:1902121	biolink:NamedThing	lithocholic acid binding	Binding to lithocholic acid.	tmpzr1t_l9r_go_relaxed.owl	LCA binding							bf	2013-05-15T16:05:12Z					molecular_function											owl:Class	
GO:0002520	biolink:NamedThing	immune system development	The process whose specific outcome is the progression of an organismal system whose objective is to provide calibrated responses by an organism to a potential internal or invasive threat, over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0006397	biolink:NamedThing	mRNA processing	Any process involved in the conversion of a primary mRNA transcript into one or more mature mRNA(s) prior to translation into polypeptide.	tmpzr1t_l9r_go_relaxed.owl	mRNA maturation													biological_process											owl:Class	
GO:0120172	biolink:NamedThing	positive regulation of actin filament bundle convergence involved in mitotic contractile ring assembly	Any process that activates or increases the frequency, rate or extent of actin filament bundle convergence involved in mitotic contractile ring assembly.	tmpzr1t_l9r_go_relaxed.owl								krc	2018-05-31T17:54:35Z					biological_process											owl:Class	
GO:0032551	biolink:NamedThing	pyrimidine ribonucleoside binding	Binding to a pyrimidine ribonucleoside, a compound consisting of a pyrimidine base linked to ribose.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0032549	biolink:NamedThing	ribonucleoside binding	Binding to a ribonucleoside, a compound consisting of a purine or pyrimidine nitrogenous base linked to ribose.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0051274	biolink:NamedThing	beta-glucan biosynthetic process	The chemical reactions and pathways resulting in the formation of beta-glucans.	tmpzr1t_l9r_go_relaxed.owl	beta-glucan anabolism|beta-glucan formation|beta-glucan synthesis|beta-glucan biosynthesis													biological_process											owl:Class	
GO:0004159	biolink:NamedThing	dihydropyrimidine dehydrogenase (NAD+) activity	Catalysis of the reaction: a 5,6-dihydropyrimidine (5,6-dihydrouracil or 5,6-dihydrothymine) + NAD+ = a pyrimidine (uracil or thymine) + NADH + H+.	tmpzr1t_l9r_go_relaxed.owl	dihydrothymine dehydrogenase (NAD+) activity|uracil reductase activity|5,6-dihydrouracil:NAD+ oxidoreductase activity|dihydrouracil dehydrogenase (NAD+) activity|thymine reductase activity|pyrimidine reductase activity	https://github.com/geneontology/go-ontology/issues/21891			EC:1.3.1.1|MetaCyc:DIHYDROURACIL-DEHYDROGENASE-NAD+-RXN									molecular_function											owl:Class	
GO:1902068	biolink:NamedThing	regulation of sphingolipid mediated signaling pathway	Any process that modulates the frequency, rate or extent of sphingolipid signaling.	tmpzr1t_l9r_go_relaxed.owl	regulation of sphingolipid signaling pathway							bf	2013-04-18T13:24:47Z					biological_process											owl:Class	
GO:0046211	biolink:NamedThing	(+)-camphor biosynthetic process	The chemical reactions and pathways resulting in the formation of (+)-camphor, a bicyclic monoterpene ketone.	tmpzr1t_l9r_go_relaxed.owl	(+)-camphor biosynthesis|(+)-camphor formation|(+)-camphor anabolism|(+)-camphor synthesis													biological_process											owl:Class	
GO:0015561	biolink:NamedThing	rhamnose:proton symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: rhamnose(out) + H+(out) = rhamnose(in) + H+(in).	tmpzr1t_l9r_go_relaxed.owl	rhamnose:hydrogen symporter activity				TC:2.A.7.6									molecular_function											owl:Class	
GO:0009679	biolink:NamedThing	hexose:proton symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: hexose(out) + H+(out) = hexose(in) + H+(in).	tmpzr1t_l9r_go_relaxed.owl	hexose:hydrogen symporter activity													molecular_function											owl:Class	
GO:0097294	biolink:NamedThing	'de novo' XMP biosynthetic process	The chemical reactions and pathways resulting in the formation of XMP, xanthosine monophosphate, from simpler precursors.	tmpzr1t_l9r_go_relaxed.owl	'de novo' XMP anabolism|'de novo' XMP biosynthesis|'de novo' XMP synthesis|'de novo' XMP formation							pr	2012-04-26T09:57:49Z					biological_process											owl:Class	
GO:0046355	biolink:NamedThing	mannan catabolic process	The chemical reactions and pathways resulting in the breakdown of mannan, the main hemicellulose of soft (coniferous) wood, made up of D-mannose, D-glucose and D-galactose.	tmpzr1t_l9r_go_relaxed.owl	mannan catabolism|mannan degradation|mannan breakdown													biological_process											owl:Class	
GO:1901890	biolink:NamedThing	positive regulation of cell junction assembly	Any process that activates or increases the frequency, rate or extent of cell junction assembly.	tmpzr1t_l9r_go_relaxed.owl	activation of cell junction assembly|up regulation of cell junction assembly|upregulation of cell junction assembly|up-regulation of cell junction assembly							tb	2013-02-06T19:40:46Z					biological_process											owl:Class	
GO:0018046	biolink:NamedThing	C-terminal peptidyl-methionine amidation	The formation of a C-terminal peptidyl-methionine amide by hydrolysis and oxidation of an interior Met-Gly peptide in a secreted protein.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0093									biological_process											owl:Class	
GO:0018033	biolink:NamedThing	protein C-terminal amidation	The formation of a C-terminal amide by hydrolysis and oxidation of an interior peptide in a secreted protein.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0075225	biolink:NamedThing	negative regulation of sporangium germination	Any process that stops, prevents, or reduces the frequency, rate or extent of sporangium germination.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of sporangium germination on or near host													biological_process											owl:Class	
GO:0075223	biolink:NamedThing	regulation of sporangium germination	Any process that modulates the frequency, rate or extent of sporangium germination.	tmpzr1t_l9r_go_relaxed.owl	modulation of sporangium germination on or near host|modulation of sporangium germination													biological_process											owl:Class	
GO:0004549	biolink:NamedThing	tRNA-specific ribonuclease activity	Catalysis of the hydrolysis of phosphodiester bonds in tRNA molecules.	tmpzr1t_l9r_go_relaxed.owl	tRNA-specific RNase activity				Reactome:R-HSA-6785722|Reactome:R-HSA-5696813|Reactome:R-HSA-5696815|Reactome:R-HSA-6786854									molecular_function											owl:Class	
GO:0031170	biolink:NamedThing	ferricrocin metabolic process	The chemical reactions and pathways involving ferricrocin, a cyclic hexapeptide siderophore with the structure Gly-Ser-Gly-(N5-acetyl-N5-hydroxyornithine)3.	tmpzr1t_l9r_go_relaxed.owl	ferricrocin metabolism													biological_process											owl:Class	
GO:0031168	biolink:NamedThing	ferrichrome metabolic process	The chemical reactions and pathways involving a ferrichrome. Ferrichromes are any of a group of growth-promoting Fe(III) chelates formed by various genera of microfungi. They are homodetic cyclic hexapeptides made up of a tripeptide of glycine (or other small neutral amino acids) and a tripeptide of an N'acyl-N4-hydroxy-L-ornithine.	tmpzr1t_l9r_go_relaxed.owl	ferrichrome metabolism													biological_process											owl:Class	
GO:0070108	biolink:NamedThing	negative regulation of interleukin-27-mediated signaling pathway	Any process that decreases the rate, frequency or extent of the series of molecular events generated as a consequence of interleukin-27 binding to a cell surface receptor.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of IL-27-mediated signaling pathway|negative regulation of IL27RA/IL6ST signaling pathway|negative regulation of interleukin-27-mediated signalling pathway													biological_process											owl:Class	
GO:0042373	biolink:NamedThing	vitamin K metabolic process	The chemical reactions and pathways involving any of the forms of vitamin K, quinone-derived vitamins which are involved in the synthesis of blood-clotting factors in mammals. Vitamin K substances share a methylated naphthoquinone ring structure and vary in the aliphatic side chains attached to the molecule.	tmpzr1t_l9r_go_relaxed.owl	naphthoquinone metabolism|naphthoquinone metabolic process|vitamin K metabolism													biological_process											owl:Class	
GO:0031915	biolink:NamedThing	positive regulation of synaptic plasticity	A process that increases synaptic plasticity, the ability of synapses to change as circumstances require. They may alter function, such as increasing or decreasing their sensitivity, or they may increase or decrease in actual numbers.	tmpzr1t_l9r_go_relaxed.owl	up regulation of synaptic plasticity|up-regulation of synaptic plasticity|stimulation of synaptic plasticity|activation of synaptic plasticity|upregulation of synaptic plasticity													biological_process											owl:Class	
GO:0120016	biolink:NamedThing	sphingolipid transfer activity	Removes a sphingolipid from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle.	tmpzr1t_l9r_go_relaxed.owl	sphingolipid carrier activity|intermembrane sphingolipid transfer activity	https://github.com/geneontology/go-ontology/issues/12329						krc	2017-03-17T03:52:30Z					molecular_function											owl:Class	
GO:0003344	biolink:NamedThing	pericardium morphogenesis	The process in which the anatomical structure of the pericardium is generated and organized.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-12-01T10:46:34Z					biological_process											owl:Class	
GO:0052321	biolink:NamedThing	negative regulation of phytoalexin metabolic process	Any process that stops, prevents, or reduces the frequency, rate or extent of phytoalexin metabolism, the chemical reactions and pathways involving phytoalexins.	tmpzr1t_l9r_go_relaxed.owl	down regulation of phytoalexin metabolism|inhibition of phytoalexin metabolism|down-regulation of phytoalexin metabolism|negative regulation of phytoalexin metabolism|downregulation of phytoalexin metabolism													biological_process											owl:Class	
GO:0046376	biolink:NamedThing	GDP-alpha-D-mannosylchitobiosyldiphosphodolichol metabolic process	The chemical reactions and pathways involving GDP-alpha-D-mannosylchitobiosyldiphosphodolichol, a substance composed of mannosylchitobiosyldiphosphodolichol in glycosidic linkage with guanosine diphosphate.	tmpzr1t_l9r_go_relaxed.owl	GDP-alpha-D-mannosylchitobiosyldiphosphodolichol metabolism													biological_process											owl:Class	
GO:0008093	biolink:NamedThing	cytoskeletal anchor activity	The binding activity of a protein that brings together a cytoskeletal protein (either a microtubule or actin filament, spindle pole body, or protein directly bound to them) and one or more other molecules, permitting them to function in a coordinated way.	tmpzr1t_l9r_go_relaxed.owl	cytoskeletal adaptor activity	https://github.com/geneontology/go-ontology/issues/19119|https://github.com/geneontology/go-ontology/issues/17668												molecular_function											owl:Class	
GO:0005334	biolink:NamedThing	norepinephrine:sodium symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: norepinephrine(out) + Na+(out) + Cl-(out) = norepinephrine(in) + Na+(in) + Cl-(in).	tmpzr1t_l9r_go_relaxed.owl	levarterenol transporter activity|norepinephrine transmembrane transporter activity|noradrenaline transporter activity|sodium/norepinephrine symporter activity|norepinephrine:sodium:chloride symporter activity				Reactome:R-HSA-5659764|Reactome:R-HSA-443997|Wikipedia:Norepinephrine_transporter							GO:0005333		molecular_function											owl:Class	
GO:0061160	biolink:NamedThing	regulation of establishment of bipolar cell polarity regulating cell shape	Any process that modulates the rate, frequency or extent of the establishment of bipolar cell polarity that contributes to the shape of a cell.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-06-23T09:21:36Z					biological_process											owl:Class	
GO:0031591	biolink:NamedThing	wybutosine biosynthetic process	The chemical reactions and pathways resulting in the formation of wybutosine, 3H-imidazo[1,2-alpha]purine-7-butanoic acid, 4,9-dihydro- alpha-[(methoxycarbonyl)amino]- 4,6-dimethyl-9-oxo- 3-beta-D-ribofuranosyl methyl ester, a modified nucleoside found in some tRNA molecules.	tmpzr1t_l9r_go_relaxed.owl	yW biosynthesis|yW biosynthetic process					Note that wybutosine is a hypermodified G-residue, formerly called the Y-base, and its derivatives are exclusively found at position 37 (anticodon loop) of tRNAPhe.								biological_process											owl:Class	
GO:1901659	biolink:NamedThing	glycosyl compound biosynthetic process	The chemical reactions and pathways resulting in the formation of glycosyl compound.	tmpzr1t_l9r_go_relaxed.owl	glycosyl compound anabolism|glycosyl compound synthesis|glycosyl compound biosynthesis|glycosyl compound formation							pr	2012-11-20T14:24:19Z					biological_process											owl:Class	
GO:0042068	biolink:NamedThing	regulation of pteridine metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving pteridine.	tmpzr1t_l9r_go_relaxed.owl	regulation of pteridine metabolism													biological_process											owl:Class	
GO:0045777	biolink:NamedThing	positive regulation of blood pressure	Any process in which the force of blood traveling through the circulatory system is increased.	tmpzr1t_l9r_go_relaxed.owl	stimulation of blood pressure|up regulation of blood pressure|upregulation of blood pressure|activation of blood pressure|up-regulation of blood pressure													biological_process											owl:Class	
GO:0032554	biolink:NamedThing	purine deoxyribonucleotide binding	Binding to a purine deoxyribonucleotide, any compound consisting of a purine deoxyribonucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the deoxyribose moiety.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0046426	biolink:NamedThing	negative regulation of receptor signaling pathway via JAK-STAT	Any process that stops, prevents, or reduces the frequency, rate or extent of a receptor signaling pathway via JAK-STAT.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of STAT protein nuclear translocation|downregulation of JAK-STAT cascade|negative regulation of STAT protein import into nucleus|down-regulation of JAK-STAT cascade|down regulation of JAK-STAT cascade|inhibition of JAK-STAT cascade											GO:2000365		biological_process											owl:Class	
GO:1904893	biolink:NamedThing	negative regulation of receptor signaling pathway via STAT	Any process that stops, prevents or reduces the frequency, rate or extent of receptor signaling via STAT.	tmpzr1t_l9r_go_relaxed.owl	inhibition of kinase-STAT cascade|down regulation of kinase activated-STAT cascade|inhibition of STAT signalling pathway|downregulation of STAT signalling pathway|downregulation of kinase-STAT cascade|down-regulation of kinase-STAT cascade|down regulation of STAT cascade|down regulation of kinase-STAT cascade|inhibition of STAT cascade|down regulation of STAT signalling pathway|negative regulation of STAT signalling pathway|down-regulation of STAT cascade|down-regulation of STAT signalling pathway|down-regulation of kinase activated-STAT cascade|downregulation of kinase activated-STAT cascade|negative regulation of kinase activated-STAT cascade|inhibition of kinase activated-STAT cascade|negative regulation of kinase-STAT cascade|downregulation of STAT cascade							pr	2016-01-08T08:14:41Z					biological_process											owl:Class	
GO:0106019	biolink:NamedThing	phosphatidylinositol-4,5-bisphosphate phosphatase activity	Catalysis of the reaction: 1-phosphatidyl-myo-inositol 4,5-bisphosphate + H2O = 1-phosphatidyl-1D-myo-inositol phosphate + phosphate.	tmpzr1t_l9r_go_relaxed.owl								hjd	2017-05-10T14:22:12Z					molecular_function											owl:Class	
GO:0034593	biolink:NamedThing	phosphatidylinositol bisphosphate phosphatase activity	Catalysis of the reaction: phosphatidylinositol bisphosphate + H2O = phosphatidylinositol phosphate + phosphate.	tmpzr1t_l9r_go_relaxed.owl	triphosphoinositide phosphomonoesterase activity|diphosphoinositide phosphatase activity|phosphatidylinositol-bisphosphatase activity|phosphatidyl-inositol-bisphosphate phosphatase activity|triphosphoinositide phosphatase activity													molecular_function											owl:Class	
GO:0043108	biolink:NamedThing	pilus retraction	The process of withdrawing a pilus back into a cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0048562	biolink:NamedThing	embryonic organ morphogenesis	Morphogenesis, during the embryonic phase, of a tissue or tissues that work together to perform a specific function or functions. Morphogenesis is the process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0046724	biolink:NamedThing	oxalic acid secretion	The controlled release of oxalic acid, ethanedioic acid, by a cell or a tissue.	tmpzr1t_l9r_go_relaxed.owl	oxalate secretion													biological_process											owl:Class	
GO:0060619	biolink:NamedThing	cell migration involved in mammary placode formation	The orderly movement of epithelial cells within the mammary line that contributes to the formation of the mammary placode.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-05-18T09:41:49Z					biological_process											owl:Class	
GO:1903751	biolink:NamedThing	negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide	Any process that stops, prevents or reduces the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to hydrogen peroxide.	tmpzr1t_l9r_go_relaxed.owl	down regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide|down-regulation of hydrogen peroxide-induced intrinsic apoptotic signaling pathway|negative regulation of hydrogen peroxide-induced intrinsic apoptotic signaling pathway|down-regulation of H2O2-induced intrinsic apoptotic signaling pathway|down regulation of intrinsic apoptotic signaling pathway in response to H2O2|inhibition of intrinsic apoptotic signaling pathway in response to hydrogen peroxide|down regulation of hydrogen peroxide-induced intrinsic apoptotic signaling pathway|downregulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide|downregulation of intrinsic apoptotic signaling pathway in response to H2O2|negative regulation of intrinsic apoptotic signaling pathway in response to H2O2|down regulation of H2O2-induced intrinsic apoptotic signaling pathway|downregulation of hydrogen peroxide-induced intrinsic apoptotic signaling pathway|down-regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide|down-regulation of intrinsic apoptotic signaling pathway in response to H2O2|downregulation of H2O2-induced intrinsic apoptotic signaling pathway|inhibition of H2O2-induced intrinsic apoptotic signaling pathway|inhibition of hydrogen peroxide-induced intrinsic apoptotic signaling pathway|inhibition of intrinsic apoptotic signaling pathway in response to H2O2|negative regulation of H2O2-induced intrinsic apoptotic signaling pathway							krc	2014-12-12T23:04:37Z					biological_process											owl:Class	
GO:2000368	biolink:NamedThing	positive regulation of acrosomal vesicle exocytosis	Any process that activates or increases the frequency, rate or extent of acrosomal vesicle exocytosis.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of acrosome exocytosis|positive regulation of acrosomal granule exocytosis							yaf	2011-02-07T11:52:42Z					biological_process											owl:Class	
GO:0042357	biolink:NamedThing	thiamine diphosphate metabolic process	The chemical reactions and pathways involving thiamine diphosphate, a derivative of thiamine (vitamin B1) which acts as a coenzyme in a range of processes including the Krebs cycle.	tmpzr1t_l9r_go_relaxed.owl	thiamine diphosphate metabolism|thiamin pyrophosphate metabolic process|thiamine pyrophosphate metabolic process|thiamin pyrophosphate metabolism|TPP metabolism|thiamine pyrophosphate metabolism|thiamin diphosphate metabolism|TPP metabolic process|thiamin diphosphate metabolic process													biological_process											owl:Class	
GO:0045947	biolink:NamedThing	negative regulation of translational initiation	Any process that stops, prevents, or reduces the frequency, rate or extent of translational initiation.	tmpzr1t_l9r_go_relaxed.owl	down regulation of translational initiation|inhibition of translational initiation|downregulation of translational initiation|down-regulation of translational initiation													biological_process											owl:Class	
GO:0019035	biolink:NamedThing	viral integration complex	A nucleoprotein complex containing viral genetic material and the viral integrase, required for genome integration into the host's genome. May contain other proteins.	tmpzr1t_l9r_go_relaxed.owl	PIC|pre-integration complex	https://github.com/geneontology/go-ontology/issues/19806			Wikipedia:Pre-integration_complex									cellular_component											owl:Class	
GO:0015389	biolink:NamedThing	pyrimidine- and adenine-specific:sodium symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: (pyrimidine nucleoside or adenine)(out) + Na+(out) = (pyrimidine nucleoside or adenine)(in) + Na+(in).	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0005415	biolink:NamedThing	nucleoside:sodium symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: nucleoside(out) + Na+(out) = nucleoside(in) + Na+(in).	tmpzr1t_l9r_go_relaxed.owl	sodium-dependent nucleoside transporter activity|nucleoside-sodium cotransporter activity				Reactome:R-HSA-109539|Reactome:R-HSA-109530|Reactome:R-HSA-109538							GO:0008522		molecular_function											owl:Class	
GO:0010961	biolink:NamedThing	cellular magnesium ion homeostasis	Any process involved in the maintenance of an internal steady state of magnesium ions at the level of a cell.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-05-06T11:48:45Z					biological_process											owl:Class	
GO:0047528	biolink:NamedThing	2,3-dihydroxyindole 2,3-dioxygenase activity	Catalysis of the reaction: 2,3-dihydroxyindole + O(2) = anthranilate + CO(2) + H(+).	tmpzr1t_l9r_go_relaxed.owl	2,3-dihydroxyindole:oxygen 2,3-oxidoreductase (decyclizing) activity				RHEA:19445|MetaCyc:23-DIHYDROXYINDOLE-23-DIOXYGENASE-RXN|EC:1.13.11.23|KEGG_REACTION:R00983									molecular_function											owl:Class	
GO:1990401	biolink:NamedThing	embryonic lung development	The process occurring during the embryonic phase whose specific outcome is the progression of the lung over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl								sl	2014-06-23T19:56:13Z					biological_process											owl:Class	
GO:0044599	biolink:NamedThing	AP-5 adaptor complex	An AP-type membrane coat adaptor complex that in humans consists of beta5, zeta, mu5 and sigma5 subunits and is found associated with membranes in the endosomes; it is not clear whether AP-5 forms clathrin coats in vivo.	tmpzr1t_l9r_go_relaxed.owl	adaptor protein-5 adaptor complex							jl	2012-05-01T03:48:11Z					cellular_component											owl:Class	
GO:0097351	biolink:NamedThing	toxin sequestering activity	Binding to a toxic protein, disabling its function. There may be more than one antitoxin to a toxic protein. Instances of this activity are known only in prokaryotes, where the toxic protein may be a ribonuclease, a DNA gyrase, or other.	tmpzr1t_l9r_go_relaxed.owl	toxin-antitoxin pair type II binding|toxin-antitoxin pair type I binding							pr	2012-06-28T11:41:38Z					molecular_function											owl:Class	
GO:1900189	biolink:NamedThing	positive regulation of cell adhesion involved in single-species biofilm formation	Any process that activates or increases the frequency, rate or extent of cell adhesion involved in single-species biofilm formation.	tmpzr1t_l9r_go_relaxed.owl	up regulation of cell adhesion during single-species biofilm formation|positive regulation of cell adhesion during single-species biofilm formation|up-regulation of cell adhesion during single-species biofilm formation|up regulation of cell adhesion involved in single-species biofilm formation|upregulation of cell adhesion involved in single-species biofilm formation|activation of cell adhesion involved in single-species biofilm formation|activation of cell adhesion during single-species biofilm formation|up-regulation of cell adhesion involved in single-species biofilm formation|upregulation of cell adhesion during single-species biofilm formation							di	2012-03-19T12:39:03Z					biological_process											owl:Class	
GO:0140501	biolink:NamedThing	positive regulation of reticulophagy	Any process that increases the frequency, rate or extent of reticulophagy.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of ER-phagy|positive regulation of endoplasmic reticulum degradation|positive regulation of ER autophagy|positive regulation of autophagy of the endoplasmic reticulum|positive regulation of endoplasmic reticulum autophagy|positive regulation of ER degradation|positive regulation of autophagy of the ER	https://github.com/geneontology/go-ontology/issues/19860						pg	2020-08-10T12:01:35Z					biological_process											owl:Class	
GO:0140357	biolink:NamedThing	heme export from vacuole to cytoplasm	The directed movement of heme from inside the vacuole across the vacuolar membrane and into the cytosol.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/17407						pg	2019-05-28T07:40:48Z					biological_process											owl:Class	
GO:0033429	biolink:NamedThing	CGU codon-amino acid adaptor activity	A triplet codon-amino acid adaptor activity that recognizes a CGU codon.	tmpzr1t_l9r_go_relaxed.owl	arginine tRNA|CGT codon-amino acid adaptor activity					Note that in the standard genetic code, CGT codes for arginine.								molecular_function											owl:Class	
GO:0062057	biolink:NamedThing	L-aspartate:fumarate antiporter activity	Enables the transport of L-aspartate and fumarate across a membrane according to the reaction L-aspartate (out) + fumarate (in) = L-aspartate (in) + fumarate (out).	tmpzr1t_l9r_go_relaxed.owl								dph	2018-08-09T14:25:45Z					molecular_function											owl:Class	
GO:1903381	biolink:NamedThing	regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway	Any process that modulates the frequency, rate or extent of an endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	regulation of neuron intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress|regulation of ER stress-induced neuron apoptosis|regulation of endoplasmic reticulum stress-induced neuron apoptosis|regulation of ER stress-induced neuron intrinsic apoptotic signaling pathway							bf	2014-08-27T08:45:29Z					biological_process											owl:Class	
GO:0050746	biolink:NamedThing	regulation of lipoprotein metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving lipoproteins, any conjugated, water-soluble protein in which the nonprotein group consists of a lipid or lipids.	tmpzr1t_l9r_go_relaxed.owl	regulation of lipoprotein metabolism													biological_process											owl:Class	
GO:0090438	biolink:NamedThing	camelliol C synthase activity	Catalyzes the reaction: (3S)-2,3-epoxy-2,3-dihydrosqualene = camelliol C.	tmpzr1t_l9r_go_relaxed.owl	(3S)-2,3-epoxy-2,3-dihydrosqualene mutase (cyclizing, camelliol-C-forming)							tb	2012-08-08T15:41:45Z					molecular_function											owl:Class	
GO:0052886	biolink:NamedThing	9,9'-dicis-carotene:quinone oxidoreductase activity	Catalysis of the reaction: 9,9'-di-cis-zeta-carotene + a quinone = 7,9,9'-tri-cis-neurosporene + a quinol.	tmpzr1t_l9r_go_relaxed.owl	zeta-carotene desaturase activity|9,9'-di-cis-zeta-carotene desaturase activity|ZDS activity				EC:1.3.5.6|RHEA:30959|MetaCyc:RXN-11356|KEGG_REACTION:R09656									molecular_function											owl:Class	
GO:0016635	biolink:NamedThing	oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces a quinone or related compound.	tmpzr1t_l9r_go_relaxed.owl					EC:1.3.5.-									molecular_function											owl:Class	
GO:0018422	biolink:NamedThing	GDP-mannose:serine-protein mannose-1-phosphotransferase activity	Catalysis of the transfer of mannose-1-phosphate to a serine residue in a protein.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0070896	biolink:NamedThing	positive regulation of transposon integration	Any process that activates or increases the frequency, rate or extent of transposon integration, a process in which a transposable element is incorporated into another DNA molecule.	tmpzr1t_l9r_go_relaxed.owl	upregulation of transposon integration|stimulation of transposon integration|activation of transposon integration|up-regulation of transposon integration|up regulation of transposon integration							mah	2009-09-01T04:25:06Z					biological_process											owl:Class	
GO:0033310	biolink:NamedThing	chlorophyll a catabolic process	The chemical reactions and pathways leading to the breakdown of chlorophyll a.	tmpzr1t_l9r_go_relaxed.owl	chlorophyll a catabolism|chlorophyll a breakdown|chlorophyll a degradation				MetaCyc:PWY-5098|MetaCyc:PWY-5086									biological_process											owl:Class	
GO:0046131	biolink:NamedThing	pyrimidine ribonucleoside metabolic process	The chemical reactions and pathways involving any ribonucleoside, a nucleoside in which pyrimidine base is linked to a ribose (beta-D-ribofuranose) molecule.	tmpzr1t_l9r_go_relaxed.owl	pyrimidine ribonucleoside metabolism													biological_process											owl:Class	
GO:0008012	biolink:NamedThing	structural constituent of adult chitin-based cuticle	The action of a molecule that contributes to the structural integrity of the chitin-based cuticle of an adult organism. An example of this is found in Drosophila melanogaster.	tmpzr1t_l9r_go_relaxed.owl	structural constituent of adult cuticle													molecular_function											owl:Class	
GO:0015704	biolink:NamedThing	cyanate transport	The directed movement of cyanate, NCO-, the anion of cyanic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0032697	biolink:NamedThing	negative regulation of interleukin-14 production	Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-14 production.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of interleukin-14 production|negative regulation of IL-14 production|negative regulation of interleukin-14 biosynthetic process|inhibition of interleukin-14 production|downregulation of interleukin-14 production|down regulation of interleukin-14 production											GO:0045370		biological_process											owl:Class	
GO:0009170	biolink:NamedThing	purine deoxyribonucleoside monophosphate metabolic process	The chemical reactions and pathways involving purine deoxyribonucleoside monophosphate, a compound consisting of a purine base linked to a deoxyribose sugar esterified with phosphate on the sugar.	tmpzr1t_l9r_go_relaxed.owl	purine deoxyribonucleoside monophosphate metabolism													biological_process											owl:Class	
GO:0032930	biolink:NamedThing	positive regulation of superoxide anion generation	Any process that activates or increases the frequency, rate or extent of enzymatic generation of superoxide by a cell.	tmpzr1t_l9r_go_relaxed.owl	stimulation of superoxide release|up-regulation of superoxide release|positive regulation of superoxide release|upregulation of superoxide release|activation of superoxide release|up regulation of superoxide release													biological_process											owl:Class	
GO:0000035	biolink:NamedThing	acyl binding	Binding to an acyl group, any group formally derived by removal of the hydroxyl group from the acid function of a carboxylic acid.	tmpzr1t_l9r_go_relaxed.owl	acyl-CoA or acyl binding													molecular_function											owl:Class	
GO:1905613	biolink:NamedThing	regulation of developmental vegetative growth	Any process that modulates the frequency, rate or extent of developmental vegetative growth.	tmpzr1t_l9r_go_relaxed.owl								pga	2016-10-28T11:45:13Z					biological_process											owl:Class	
GO:0015869	biolink:NamedThing	protein-DNA complex transport	The directed movement of protein-DNA complexes into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	DNA-protein complex transport													biological_process											owl:Class	
GO:0032489	biolink:NamedThing	regulation of Cdc42 protein signal transduction	Any process that modulates the frequency, rate or extent of Cdc42 protein signal transduction.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:2000633	biolink:NamedThing	positive regulation of pre-miRNA processing	Any process that activates or increases the frequency, rate or extent of pre-microRNA processing.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of pre-microRNA processing							dph	2011-04-18T03:50:22Z					biological_process											owl:Class	
GO:0005672	biolink:NamedThing	transcription factor TFIIA complex	A component of the transcription machinery of RNA Polymerase II. In humans, TFIIA is a heterotrimer composed of an alpha (P35), beta (P19) and gamma subunits (P12).	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0098980	biolink:NamedThing	presynaptic density	An electron dense specialization of the presynaptic active zone cytoskeleton.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0048788	biolink:NamedThing	cytoskeleton of presynaptic active zone	The specialized cytoskeletal matrix of the presynaptic active zone. It has specialized functions in organizing synaptic events such as immobilisation or translocation of synaptic vesicles, and assembling active zone components. It is believed to form a molecular scaffold that organizes neurotransmitter release sites.	tmpzr1t_l9r_go_relaxed.owl	T-bar ribbon|presynaptic cytoskeletal matrix|pre-synaptic ribbon|presynaptic dense body|active zone cytomatrix|ribbon|T-bar|pre-synaptic dense body|CAZ|presynaptic ribbon|presynaptic cytoskeletal matrix assembled at active zones|presynaptic cytomatrix assembled at active zones|synaptic ribbon|pre-synaptic cytoskeletal matrix assembled at active zones				NIF_Subcellular:sao1470121605									cellular_component											owl:Class	
GO:0090024	biolink:NamedThing	negative regulation of neutrophil chemotaxis	Any process that decreases the frequency, rate, or extent of neutrophil chemotaxis. Neutrophil chemotaxis is the directed movement of a neutrophil cell, the most numerous polymorphonuclear leukocyte found in the blood, in response to an external stimulus, usually an infection or wounding.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-08-03T10:13:09Z					biological_process											owl:Class	
GO:0044348	biolink:NamedThing	plant-type cell wall cellulose catabolic process	The chemical reactions and pathways resulting in the breakdown of cellulose, a linear beta1-4 glucan of molecular mass 50-400 kDa with the pyranose units in the -4C1 conformation, which forms part of the cell wall.	tmpzr1t_l9r_go_relaxed.owl	plant-type cell wall polysaccharide breakdown							jl	2011-07-28T01:48:23Z					biological_process											owl:Class	
GO:0052541	biolink:NamedThing	plant-type cell wall cellulose metabolic process	The chemical reactions and pathways involving cellulose, a linear beta1-4 glucan of molecular mass 50-400 kDa with the pyranose units in the -4C1 conformation, as part of the organization and biogenesis of the cell wall.	tmpzr1t_l9r_go_relaxed.owl	cell wall cellulose metabolism|cellulose and pectin-containing cell wall cellulose metabolic process													biological_process											owl:Class	
GO:0044603	biolink:NamedThing	protein adenylylhydrolase activity	Catalysis of the reaction: adenylyl-protein+ H2O = adenylate + protein; mediates the removal of an adenylyl (adenosine 5'-monophosphate; AMP group) from specific residues of target proteins.	tmpzr1t_l9r_go_relaxed.owl	protein deAMPylation activity|protein deAMPylase activity							jl	2012-05-01T04:18:07Z					molecular_function											owl:Class	
GO:0140421	biolink:NamedThing	endocytic heme import into cell	The directed movement into cell of externally available heme by receptor-mediated endocytosis.	tmpzr1t_l9r_go_relaxed.owl	heme assimilation	https://github.com/geneontology/go-ontology/issues/18671						pg	2020-01-30T13:14:02Z					biological_process											owl:Class	
GO:0050075	biolink:NamedThing	maleate hydratase activity	Catalysis of the reaction: (R)-malate = H(2)O + maleate.	tmpzr1t_l9r_go_relaxed.owl	malease activity|(R)-malate hydro-lyase activity|D-malate hydro-lyase activity|(R)-malate hydro-lyase (maleate-forming)				KEGG_REACTION:R02419|EC:4.2.1.31|RHEA:23692|MetaCyc:MALEATE-HYDRATASE-RXN									molecular_function											owl:Class	
GO:0006540	biolink:NamedThing	glutamate decarboxylation to succinate	The chemical reactions and pathways resulting in the formation of succinate from glutamate. Also known as GABA (gamma-aminobutyrate) shunt since it channels glutamate into the TCA cycle bypassing two steps of that cycle. There are three enzymes involved in the GABA shunt: glutamate decarboxylase (GAD), GABA aminotransferase (GABA-TA), and succinate semialdehyde dehydrogenase (SSADH). These three enzymes acting in concert to convert glutamate into succinate. The GABA shunt is predominantly associated with neurotransmission in the mammalian brain. It is also present in nonneuronal cells, in plants, in unicellular eukaryotes, and in prokaryotes.	tmpzr1t_l9r_go_relaxed.owl	4-aminobutyrate shunt|glutamate degradation via 4-aminobutyrate|degradation of glutamate to succinate through GABA|glutamate degradation via GABA|GABA shunt|gamma-aminobutyrate shunt				MetaCyc:PWY-4321|MetaCyc:GLUDEG-I-PWY|MetaCyc:PWY3O-210	Note that the third step in this pathway (conversion of succinate semialdehyde to succinate) can be catalyzed by NAD-dependent or NADP-dependent succinate semialdehyde dehydrogenase (EC:1.2.1.24 and EC:1.2.1.79, respectively).								biological_process											owl:Class	
GO:0006538	biolink:NamedThing	glutamate catabolic process	The chemical reactions and pathways resulting in the breakdown of glutamate, the anion of 2-aminopentanedioic acid.	tmpzr1t_l9r_go_relaxed.owl	glutamic acid catabolic process|glutamate degradation|glutamate deamidation|glutamate catabolism|glutamic acid catabolism|glutamate breakdown											GO:0019459		biological_process											owl:Class	
GO:0009290	biolink:NamedThing	DNA import into cell involved in transformation	The directed movement of DNA into a cell that contributes to the process of transformation, the uptake of foreign genetic material into a cell.	tmpzr1t_l9r_go_relaxed.owl	cellular DNA uptake|DNA transport into cell during transformation|cellular DNA import during transformation|DNA import into cell													biological_process											owl:Class	
GO:0051027	biolink:NamedThing	DNA transport	The directed movement of RNA, deoxyribonucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0001876	biolink:NamedThing	lipoarabinomannan binding	Binding to lipoarabinomannan.	tmpzr1t_l9r_go_relaxed.owl	LAM binding													molecular_function											owl:Class	
GO:1901469	biolink:NamedThing	regulation of syringal lignin catabolic process	Any process that modulates the frequency, rate or extent of syringal lignin catabolic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of syringal lignin breakdown|regulation of syringal lignin catabolism|regulation of S-lignin catabolic process|regulation of syringal lignin degradation							tt	2012-10-02T14:41:12Z					biological_process											owl:Class	
GO:0071440	biolink:NamedThing	regulation of histone H3-K14 acetylation	Any process that modulates the frequency, rate or extent of the addition of an acetyl group to histone H3 at position 14 of the histone.	tmpzr1t_l9r_go_relaxed.owl	regulation of histone H3 acetylation at K14|regulation of histone H3K14 acetylation							mah	2009-12-16T03:24:53Z					biological_process											owl:Class	
GO:1903389	biolink:NamedThing	negative regulation of synaptic vesicle uncoating	Any process that stops, prevents or reduces the frequency, rate or extent of synaptic vesicle uncoating.	tmpzr1t_l9r_go_relaxed.owl	downregulation of synaptic vesicle coat depolymerization|inhibition of synaptic vesicle coat protein depolymerization|down regulation of synaptic vesicle coat depolymerization|negative regulation of synaptic vesicle coat protein depolymerization|down-regulation of synaptic vesicle coat protein depolymerization|inhibition of synaptic vesicle uncoating|down regulation of synaptic vesicle uncoating|inhibition of synaptic vesicle coat depolymerization|down regulation of synaptic vesicle coat protein depolymerization|negative regulation of synaptic vesicle coat depolymerization|down-regulation of synaptic vesicle coat depolymerization|downregulation of synaptic vesicle coat protein depolymerization|downregulation of synaptic vesicle uncoating|down-regulation of synaptic vesicle uncoating							pad	2014-08-27T10:03:02Z					biological_process											owl:Class	
GO:0090597	biolink:NamedThing	nematode male tail mating organ morphogenesis	The process in which the anatomical structures of the nematode male tail mating organ are generated and organized. The male tail is a sensory organ required for mating and, in C. elegans, consists of ray sensilla, an acellular cuticular fan, a sensory hook, and protracting, copulatory spicules.	tmpzr1t_l9r_go_relaxed.owl								tb	2014-08-22T13:25:22Z					biological_process											owl:Class	
GO:0048808	biolink:NamedThing	male genitalia morphogenesis	The process in which the anatomical structures of male genitalia are generated and organized.	tmpzr1t_l9r_go_relaxed.owl	male genital morphogenesis													biological_process											owl:Class	
GO:0009081	biolink:NamedThing	branched-chain amino acid metabolic process	The chemical reactions and pathways involving amino acids containing a branched carbon skeleton, comprising isoleucine, leucine and valine.	tmpzr1t_l9r_go_relaxed.owl	branched chain family amino acid metabolism													biological_process											owl:Class	
GO:0033336	biolink:NamedThing	caudal fin development	The process whose specific outcome is the progression of the caudal fin over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0033338	biolink:NamedThing	medial fin development	The process whose specific outcome is the progression of a medial fin over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl	median fin development													biological_process											owl:Class	
GO:0033858	biolink:NamedThing	N-acetylgalactosamine kinase activity	Catalysis of the reaction: ATP + N-acetyl-D-galactosamine = ADP + N-acetyl-alpha-D-galactosamine 1-phosphate.	tmpzr1t_l9r_go_relaxed.owl	N-acetylgalactosamine (GalNAc)-1-phosphate kinase activity|ATP:N-acetyl-D-galactosamine 1-phosphotransferase activity|GalNAc kinase activity|GK2|GALK2				MetaCyc:2.7.1.157-RXN|RHEA:12617|EC:2.7.1.157									molecular_function											owl:Class	
GO:0010826	biolink:NamedThing	negative regulation of centrosome duplication	Any process that decreases the frequency, rate or extent of centrosome duplication. Centrosome duplication is the replication of a centrosome, a structure comprised of a pair of centrioles and peri-centriolar material from which a microtubule spindle apparatus is organized.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0010824	biolink:NamedThing	regulation of centrosome duplication	Any process that modulates the frequency, rate or extent of centrosome duplication. Centrosome duplication is the replication of a centrosome, a structure comprised of a pair of centrioles and peri-centriolar material from which a microtubule spindle apparatus is organized.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0007584	biolink:NamedThing	response to nutrient	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nutrient stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to nutrients|nutritional response pathway													biological_process											owl:Class	
GO:0031667	biolink:NamedThing	response to nutrient levels	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of nutrients.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0019276	biolink:NamedThing	UDP-N-acetylgalactosamine metabolic process	The chemical reactions and pathways involving UDP-N-acetylgalactosamine, a substance composed of N-acetylgalactosamine, a common structural unit of oligosaccharides, in glycosidic linkage with uridine diphosphate.	tmpzr1t_l9r_go_relaxed.owl	UDP-N-acetylgalactosamine metabolism													biological_process											owl:Class	
GO:0008203	biolink:NamedThing	cholesterol metabolic process	The chemical reactions and pathways involving cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones. It is a component of the plasma membrane lipid bilayer and of plasma lipoproteins and can be found in all animal tissues.	tmpzr1t_l9r_go_relaxed.owl	cholesterol metabolism													biological_process											owl:Class	
GO:0051425	biolink:NamedThing	PTB domain binding	Binding to a phosphotyrosine-binding (PTB) Binding to a phosphotyrosine-bindin domain.	tmpzr1t_l9r_go_relaxed.owl	PID binding|phosphotyrosine-interacting domain binding													molecular_function											owl:Class	
GO:0071787	biolink:NamedThing	endoplasmic reticulum tubular network formation	The aggregation, arrangement and bonding together of a set of components to form the endoplasmic reticulum (ER) tubular network. The ER tubular network is the ER part that comprises the membranes with high curvature in cross-section.	tmpzr1t_l9r_go_relaxed.owl	ER tubular network assembly|ER tubular network formation|endoplasmic reticulum tubular network assembly							mah	2010-09-01T01:54:29Z					biological_process											owl:Class	
GO:0032980	biolink:NamedThing	keratinocyte activation	A change in the morphology or behavior of a keratinocyte resulting from exposure to an activating factor such as a cellular or soluble ligand. Upon activation, keratinocytes become migratory and hyperproliferative, and produce growth factors and cytokines.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0060302	biolink:NamedThing	negative regulation of cytokine activity	Any process that decreases the rate, frequency or extent of the activity of a molecule that controls the survival, growth, differentiation and effector function of tissues and cells.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0072099	biolink:NamedThing	anterior/posterior pattern specification involved in ureteric bud development	The developmental process that results in the creation of defined areas or spaces within the ureteric bud along the anterior/posterior axis to which cells respond and eventually are instructed to differentiate.	tmpzr1t_l9r_go_relaxed.owl	ureteric bud anterior/posterior pattern formation							mah	2010-02-10T02:12:09Z					biological_process											owl:Class	
GO:0072098	biolink:NamedThing	anterior/posterior pattern specification involved in kidney development	The developmental process that results in the creation of defined areas or spaces within the kidney along the anterior/posterior axis to which cells respond and eventually are instructed to differentiate.	tmpzr1t_l9r_go_relaxed.owl	kidney anterior/posterior pattern specification|anterior/posterior pattern formation involved in kidney development|kidney anterior/posterior pattern formation							mah	2010-02-10T02:06:24Z					biological_process											owl:Class	
GO:0046293	biolink:NamedThing	formaldehyde biosynthetic process	The chemical reactions and pathways resulting in the formation of formaldehyde (methanal, H2C=O), the simplest aldehyde.	tmpzr1t_l9r_go_relaxed.owl	methanal biosynthetic process|methanal biosynthesis|formaldehyde anabolism|formaldehyde formation|formaldehyde synthesis|formaldehyde biosynthesis													biological_process											owl:Class	
GO:0031442	biolink:NamedThing	positive regulation of mRNA 3'-end processing	Any process that activates or increases the frequency, rate or extent of mRNA 3'-end processing.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of mRNA 3'-end processing|activation of mRNA 3'-end processing|stimulation of mRNA 3'-end processing|upregulation of mRNA 3'-end processing|up regulation of mRNA 3'-end processing													biological_process											owl:Class	
GO:0050685	biolink:NamedThing	positive regulation of mRNA processing	Any process that activates or increases the frequency, rate or extent of mRNA processing.	tmpzr1t_l9r_go_relaxed.owl	stimulation of mRNA processing|up-regulation of mRNA processing|activation of mRNA processing|upregulation of mRNA processing|up regulation of mRNA processing													biological_process											owl:Class	
GO:0009998	biolink:NamedThing	negative regulation of retinal cone cell fate specification	Any process that restricts, stops or prevents a cell from specifying into a retinal cone cell.	tmpzr1t_l9r_go_relaxed.owl	suppression of retinal cone cell fate|down regulation of retinal cone cell fate specification|down-regulation of retinal cone cell fate specification|suppression of retina cone cell fate|negative regulation of retina cone cell fate specification|downregulation of retinal cone cell fate specification|inhibition of retinal cone cell fate specification													biological_process											owl:Class	
GO:0018693	biolink:NamedThing	ethylbenzene hydroxylase activity	Catalysis of the reaction: A + ethylbenzene + H(2)O = (S)-1-phenylethanol + AH(2).	tmpzr1t_l9r_go_relaxed.owl	ethylbenzene:(acceptor) oxidoreductase activity|ethylbenzene dehydrogenase activity				RHEA:17897|UM-BBD_reactionID:r0234|MetaCyc:RXN-1301|KEGG_REACTION:R05745|EC:1.17.99.2									molecular_function											owl:Class	
GO:0010555	biolink:NamedThing	response to mannitol	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mannitol stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to mannitol stimulus													biological_process											owl:Class	
GO:2001019	biolink:NamedThing	positive regulation of retrograde axon cargo transport	Any process that activates or increases the frequency, rate or extent of retrograde axon cargo transport.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of retrograde axonal transport							kmv	2011-08-11T09:44:49Z					biological_process											owl:Class	
GO:0106280	biolink:NamedThing	positive regulation of UDP-N-acetylglucosamine biosynthetic process	Any process that activates or increases the frequency, rate or extent of the UDP-N-acetylglucosamine biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of UDP-GlcNAc biosynthetic process|positive regulation of UDP-N-acetylglucosamine biosynthesis|positive regulation of UDP-N-acetylglucosamine anabolism|positive regulation of UDP-N-acetylglucosamine synthesis|positive egulation of UDP-N-acetylglucosamine formation							hjd	2020-07-09T18:12:08Z					biological_process											owl:Class	
GO:0085019	biolink:NamedThing	formation of tubovesicular network for nutrient acquisition	The assembly of a symbiont-induced complex organelle that comprises of multiple protein and lipid domains for the purpose of obtaining nutrients from its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	formation of a symbiont- induced tubovesicular network for nutrient acquisition from host|formation by symbiont of a tubovesicular network for nutrient acquisition from host	https://github.com/geneontology/go-ontology/issues/20305						jl	2010-05-20T04:29:24Z					biological_process											owl:Class	
GO:0052093	biolink:NamedThing	formation of specialized structure for nutrient acquisition	The assembly of a symbiotic cellular or anatomical structure for the purpose of obtaining nutrients from its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	formation by symbiont of specialized structure for nutrient acquisition from host|formation by organism of specialized structure for nutrient acquisition from host|formation of specialized structure for nutrient acquisition from host	https://github.com/geneontology/go-ontology/issues/20305												biological_process											owl:Class	
GO:0039624	biolink:NamedThing	viral outer capsid	The outer layer of a double or triple concentric icosahedral capsid. Outer capsids are part of reoviridae and cystoviridae virions.	tmpzr1t_l9r_go_relaxed.owl	outer capsid							bf	2012-07-18T04:03:16Z					cellular_component											owl:Class	
GO:0044056	biolink:NamedThing	modulation by symbiont of host digestive system process	The alteration by a symbiont organism of the functioning of a digestive system process, a physical, chemical, or biochemical process carried out by the host organism to break down ingested nutrients into components that may be easily absorbed and directed into metabolism.	tmpzr1t_l9r_go_relaxed.owl	regulation by symbiont of host digestive system process													biological_process											owl:Class	
GO:0035118	biolink:NamedThing	embryonic pectoral fin morphogenesis	The process, occurring in the embryo, by which the anatomical structures of the pectoral fin are generated and organized. Pectoral fins are bilaterally paired fins mounted laterally and located behind the gill covers of fish. These fins are used for lateral mobility and propulsion.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0035113	biolink:NamedThing	embryonic appendage morphogenesis	The process, occurring in the embryo, by which the anatomical structures of the appendage are generated and organized. An appendage is an organ or part that is attached to the trunk of an organism, such as a limb or a branch.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0019732	biolink:NamedThing	antifungal humoral response	An immune response against a fungus mediated through a body fluid. An example of this process is the antifungal humoral response in Drosophila melanogaster.	tmpzr1t_l9r_go_relaxed.owl												GO:0006966|GO:0019734		biological_process											owl:Class	
GO:0016002	biolink:NamedThing	sulfite reductase activity	Catalysis of the reaction: hydrogen sulfide + acceptor + 3 H2O = sulfite + reduced acceptor.	tmpzr1t_l9r_go_relaxed.owl	assimilatory-type sulfite reductase activity|siroheme sulfite reductase activity|sulphite reductase activity|hydrogen-sulfide:acceptor oxidoreductase activity|hydrogen-sulfide:(acceptor) oxidoreductase activity|assimilatory sulfite reductase activity				MetaCyc:SULFITE-REDUCTASE-RXN									molecular_function											owl:Class	
GO:0022885	biolink:NamedThing	bacteriocin transmembrane transporter activity	Enables the transfer of a bacteriocin from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0102678	biolink:NamedThing	22-alpha-hydroxy-campest-4-en-3-one,NADPH:steroid 5alpha-reductase activity	Catalysis of the reaction: (5alpha,22S,24R)-22-hydroxyergostan-3-one + NADP <=> H+ + (22S)-22-hydroxycampest-4-en-3-one + NADPH.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-4229									molecular_function											owl:Class	
GO:2000844	biolink:NamedThing	negative regulation of testosterone secretion	Any process that stops, prevents or reduces the frequency, rate or extent of testosterone secretion.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-07-26T08:42:33Z					biological_process											owl:Class	
GO:0052764	biolink:NamedThing	exo-oligoalginate lyase activity	Catalysis of the cleavage of glycosidic bonds through a beta-elimination reaction on alginate, a linear polysaccharide consisting of guluronate (G) and mannuronate (M) as the monomer constituents. An oligoalginate is a linear polymer of two, three or four units of (1->4)-alpha-L-guluronic acid and beta-D-mannuronic acid, releasing monosaccharides with 4-deoxy-alpha-L-erythro-hex-4-enopyranuronosyl groups at their ends.	tmpzr1t_l9r_go_relaxed.owl					EC:4.2.2.26			ai	2011-09-29T04:05:44Z					molecular_function											owl:Class	
GO:0075330	biolink:NamedThing	positive regulation of arbuscule formation for nutrient acquisition from host	Any process that activates or increases the frequency, rate or extent of symbiont arbuscule formation for nutrient acquisition from host. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl						Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products from the symbiont involved in this process.								biological_process											owl:Class	
GO:0060299	biolink:NamedThing	negative regulation of sarcomere organization	Any process that decreases the rate, frequency or extent of myofibril assembly by organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of sarcomere organisation													biological_process											owl:Class	
GO:1905792	biolink:NamedThing	positive regulation of mechanosensory behavior	Any process that activates or increases the frequency, rate or extent of mechanosensory behavior.	tmpzr1t_l9r_go_relaxed.owl	upregulation of mechanosensory behaviour|up-regulation of mechanosensory behaviour|activation of mechanosensory behaviour|up regulation of mechanosensory behavior|upregulation of behavioral response to mechanical stimulus|positive regulation of behavioral response to mechanical stimulus|up regulation of behavioral response to mechanical stimulus|upregulation of behavioural response to mechanical stimulus|activation of behavioural response to mechanical stimulus|upregulation of mechanosensory behavior|positive regulation of mechanosensory behaviour|activation of behavioral response to mechanical stimulus|activation of mechanosensory behavior|positive regulation of behavioural response to mechanical stimulus|up regulation of mechanosensory behaviour|up-regulation of behavioural response to mechanical stimulus|up-regulation of behavioral response to mechanical stimulus|up-regulation of mechanosensory behavior|up regulation of behavioural response to mechanical stimulus							hbye	2017-01-09T15:17:24Z					biological_process											owl:Class	
GO:0043981	biolink:NamedThing	histone H4-K5 acetylation	The modification of histone H4 by the addition of an acetyl group to a lysine residue at position 5 of the histone.	tmpzr1t_l9r_go_relaxed.owl	histone H4 acetylation at K5													biological_process											owl:Class	
GO:0043967	biolink:NamedThing	histone H4 acetylation	The modification of histone H4 by the addition of an acetyl group.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0005436	biolink:NamedThing	sodium:phosphate symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Na+(out) + phosphate(out) = Na+(in) + phosphate(in).	tmpzr1t_l9r_go_relaxed.owl	sodium/phosphate symporter activity|sodium-dependent phosphate transmembrane transporter activity	https://github.com/geneontology/go-ontology/issues/18577			Reactome:R-HSA-5625123|Reactome:R-HSA-5651697|Reactome:R-HSA-427605|Reactome:R-HSA-2872498|Reactome:R-HSA-427656|Reactome:R-HSA-5687585|Reactome:R-HSA-427645|Reactome:R-HSA-428609|Reactome:R-HSA-5651971|Reactome:R-HSA-5651685							GO:0015321		molecular_function											owl:Class	
GO:0034254	biolink:NamedThing	regulation of urea catabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of urea.	tmpzr1t_l9r_go_relaxed.owl	regulation of urea breakdown|regulation of urea degradation|regulation of urea catabolism													biological_process											owl:Class	
GO:0071492	biolink:NamedThing	cellular response to UV-A	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-A radiation stimulus. UV-A radiation (UV-A light) spans the wavelengths 315 to 400 nm.	tmpzr1t_l9r_go_relaxed.owl	cellular response to UVA radiation stimulus|cellular response to UVA light stimulus|cellular response to UV-A radiation stimulus|cellular response to UV-A light stimulus							mah	2009-12-18T02:21:51Z					biological_process											owl:Class	
GO:0034644	biolink:NamedThing	cellular response to UV	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ultraviolet radiation (UV light) stimulus. Ultraviolet radiation is electromagnetic radiation with a wavelength in the range of 10 to 380 nanometers.	tmpzr1t_l9r_go_relaxed.owl	cellular response to UV radiation stimulus|cellular response to ultraviolet light stimulus|cellular response to UV light stimulus|cellular response to ultraviolet radiation stimulus													biological_process											owl:Class	
GO:0019758	biolink:NamedThing	glycosinolate biosynthetic process	The chemical reactions and pathways resulting in the formation of glycosinolates, substituted thioglycosides found in rapeseed products and related cruciferae.	tmpzr1t_l9r_go_relaxed.owl	glycosinolate formation|glycosinolate biosynthesis|glycosinolate synthesis|glycosinolate anabolism													biological_process											owl:Class	
GO:0019757	biolink:NamedThing	glycosinolate metabolic process	The chemical reactions and pathways involving glycosinolates, substituted thioglycosides found in rapeseed products and related cruciferae.	tmpzr1t_l9r_go_relaxed.owl	glycosinolate metabolism													biological_process											owl:Class	
GO:2001232	biolink:NamedThing	positive regulation of protein localization to prospore membrane	Any process that activates or increases the frequency, rate or extent of protein localization to prospore membrane.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of protein-prospore membrane targeting|positive regulation of protein targeting to forespore membrane|positive regulation of protein targeting to prospore membrane|positive regulation of protein localisation to prospore membrane|positive regulation of protein targeting to ascospore-type prospore membrane|positive regulation of protein targeting to FSM							mah	2011-11-21T04:13:36Z					biological_process											owl:Class	
GO:0097308	biolink:NamedThing	cellular response to farnesol	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a farnesol stimulus.	tmpzr1t_l9r_go_relaxed.owl								pr	2012-05-15T03:54:01Z					biological_process											owl:Class	
GO:0019219	biolink:NamedThing	regulation of nucleobase-containing compound metabolic process	Any cellular process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids.	tmpzr1t_l9r_go_relaxed.owl	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism|regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process													biological_process											owl:Class	
GO:1901994	biolink:NamedThing	negative regulation of meiotic cell cycle phase transition	Any process that stops, prevents or reduces the frequency, rate or extent of meiotic cell cycle phase transition.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of cell cycle transition|downregulation of cell cycle transition|downregulation of meiotic cell cycle phase transition|inhibition of meiotic cell cycle phase transition|down-regulation of cell cycle transition|down regulation of cell cycle transition|inhibition of cell cycle transition|down regulation of meiotic cell cycle phase transition|down-regulation of meiotic cell cycle phase transition							jl	2013-03-19T16:15:03Z					biological_process											owl:Class	
GO:1901993	biolink:NamedThing	regulation of meiotic cell cycle phase transition	Any process that modulates the frequency, rate or extent of meiotic cell cycle phase transition.	tmpzr1t_l9r_go_relaxed.owl	regulation of cell cycle transition|meiotic cell cycle control							jl	2013-03-19T16:14:58Z					biological_process											owl:Class	
GO:0034770	biolink:NamedThing	histone H4-K20 methylation	The modification of histone H4 by addition of one or more methyl groups to lysine at position 20 of the histone.	tmpzr1t_l9r_go_relaxed.owl	histone H4 K20 methylation|histone lysine H4 K20 methylation|histone H4K20me													biological_process											owl:Class	
GO:0060732	biolink:NamedThing	positive regulation of inositol phosphate biosynthetic process	Any process that increases the rate, frequency or extent of inositol phosphate biosynthesis. Inositol phosphate biosynthetic processes are the chemical reactions and pathways resulting in the formation of an inositol phosphate, 1,2,3,4,5,6-cyclohexanehexol, with one or more phosphate groups attached.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-06-12T01:58:23Z					biological_process											owl:Class	
GO:0009418	biolink:NamedThing	pilus shaft	The long, slender, mid section of a pilus.	tmpzr1t_l9r_go_relaxed.owl	fimbrial shaft													cellular_component											owl:Class	
GO:0036108	biolink:NamedThing	4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of 4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate, a precursor of 4-amino-4-deoxy-L-arabinose (L-Ara4N).	tmpzr1t_l9r_go_relaxed.owl	4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate formation|4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate anabolism|4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate synthesis|undecaprenyl phosphate alpha-L-Ara4N biosynthesis|4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate biosynthesis							bf	2012-02-06T02:58:03Z					biological_process											owl:Class	
GO:0035000	biolink:NamedThing	oligosaccharyltransferase III complex	An oligosaccharyltransferase (OST) complex that contains the seven polypeptides found in OST complex I, plus heterotrimeric Sec61alpha-beta-gamma and the tetrameric TRAP complex. Of the three forms of mammalian OST complexes identified, the OSTIII complex has the strongest affinity for ribosomes.	tmpzr1t_l9r_go_relaxed.owl	OSTCIII													cellular_component											owl:Class	
GO:0071081	biolink:NamedThing	alpha3-beta1 integrin-CD63 complex	A protein complex that consists of an alpha3-beta1 integrin complex bound to the tetraspanin CD63.	tmpzr1t_l9r_go_relaxed.owl	ITGA3-ITGB1-CD63 complex							mah	2009-11-06T04:43:43Z					cellular_component											owl:Class	
GO:0098678	biolink:NamedThing	viral tropism switching	A process by which the range of hosts which a virus can bind and infect is changed.  Examples include phages that switch between types of fibers via the action of a virally encoded invertase.	tmpzr1t_l9r_go_relaxed.owl					VZ:4498			dos	2017-01-19T13:05:51Z					biological_process											owl:Class	
GO:0047385	biolink:NamedThing	[3-methyl-2-oxobutanoate dehydrogenase (lipoamide)]-phosphatase activity	Catalysis of the reaction: H2O + [3-methyl-2-oxobutanoate dehydrogenase (lipoamide)] phosphate = phosphate + [3-methyl-2-oxobutanoate dehydrogenase (lipoamide)].	tmpzr1t_l9r_go_relaxed.owl	branched-chain oxo-acid dehydrogenase phosphatase activity|branched-chain 2-keto acid dehydrogenase phosphatase activity|3-methyl-2-oxobutanoate dehydrogenase (lipoamide)-phosphatase activity|3-methyl-2-oxobutanoate dehydrogenase (lipoamide)-phosphate phosphohydrolase activity|branched-chain alpha-keto acid dehydrogenase phosphatase				MetaCyc:3.1.3.52-RXN|EC:3.1.3.52									molecular_function											owl:Class	
GO:0030391	biolink:NamedThing	fructosamine biosynthetic process	The chemical reactions and pathways resulting in the formation of fructosamine, a fructose molecule containing an amino group in place of a hydroxyl group.	tmpzr1t_l9r_go_relaxed.owl	fructosamine synthesis|fructosamine anabolism|fructosamine biosynthesis|fructosamine formation													biological_process											owl:Class	
GO:0070703	biolink:NamedThing	outer mucus layer	The outer of two mucus layers secreted by epithelial cells in the colon; the outer mucus layer is loosely packed and can be colonized by bacteria.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-06-08T02:44:51Z					cellular_component											owl:Class	
GO:0070701	biolink:NamedThing	mucus layer	An extracellular region part that consists of a protective layer of mucus secreted by epithelial cells lining tubular organs of the body such as the colon or secreted into fluids such as saliva. Mucus is a viscous slimy secretion consisting of mucins (i.e. highly glycosylated mucin proteins) and various inorganic salts dissolved in water, with suspended epithelial cells and leukocytes.	tmpzr1t_l9r_go_relaxed.owl	mucous layer|mucous|extracellular proteinaceous gel|mucus							mah	2009-06-08T02:31:34Z					cellular_component											owl:Class	
GO:0044617	biolink:NamedThing	modulation of relaxation of smooth muscle in other organism	The process in which an organism effects a change in the relaxation of smooth muscle in a second organism.	tmpzr1t_l9r_go_relaxed.owl	regulation of relaxation of smooth muscle in other organism							jl	2012-07-04T01:55:37Z					biological_process											owl:Class	
GO:1901080	biolink:NamedThing	regulation of relaxation of smooth muscle	Any process that modulates the frequency, rate or extent of relaxation of smooth muscle.	tmpzr1t_l9r_go_relaxed.owl	regulation of smooth muscle relaxation							jl	2012-07-04T10:45:09Z					biological_process											owl:Class	
GO:0031592	biolink:NamedThing	centrosomal corona	An amorphous structure surrounding the core of the centrosome, from which microtubules are nucleated; contains gamma-tubulin.	tmpzr1t_l9r_go_relaxed.owl						Note that the centrosomal corona has been observed in Dictyostelium, and is the functional equivalent of pericentriolar material.								cellular_component											owl:Class	
GO:2000208	biolink:NamedThing	positive regulation of ribosomal small subunit export from nucleus	Any process that activates or increases the frequency, rate or extent of ribosomal small subunit export from nucleus.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of 40S ribosomal subunit export from nucleus|positive regulation of ribosomal small subunit transport from nucleus to cytoplasm|positive regulation of 30S ribosomal subunit export from nucleus|positive regulation of ribosomal small subunit export out of nucleus|positive regulation of ribosomal small subunit export from cell nucleus|positive regulation of ribosomal small subunit-nucleus export							mah	2010-10-26T10:54:16Z					biological_process											owl:Class	
GO:1903879	biolink:NamedThing	11beta-hydroxyprogesterone binding	Binding to 11beta-hydroxyprogesterone.	tmpzr1t_l9r_go_relaxed.owl								mr	2015-02-06T16:03:12Z					molecular_function											owl:Class	
GO:0034402	biolink:NamedThing	recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex	The process in which proteins required for 3'-end transcript processing become associated with the RNA polymerase II holoenzyme complex and the 3' end of a transcript.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1903729	biolink:NamedThing	regulation of plasma membrane organization	Any process that modulates the frequency, rate or extent of plasma membrane organization.	tmpzr1t_l9r_go_relaxed.owl	regulation of plasma membrane organisation|regulation of plasma membrane organization and biogenesis							al	2014-12-10T18:59:44Z					biological_process											owl:Class	
GO:0006338	biolink:NamedThing	chromatin remodeling	Dynamic structural changes to eukaryotic chromatin occurring throughout the cell division cycle. These changes range from the local changes necessary for transcriptional regulation to global changes necessary for chromosome segregation.	tmpzr1t_l9r_go_relaxed.owl	ATP-dependent chromatin remodelling|chromatin remodelling|ATP-dependent chromatin remodeling|chromatin modeling|chromatin modelling	https://github.com/geneontology/go-ontology/issues/21732										GO:0043044		biological_process											owl:Class	
GO:0035962	biolink:NamedThing	response to interleukin-13	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-13 stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to IL-13							bf	2011-08-01T11:29:02Z					biological_process											owl:Class	
GO:0090208	biolink:NamedThing	positive regulation of triglyceride metabolic process	Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving triglyceride, any triester of glycerol.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-12-23T10:35:06Z					biological_process											owl:Class	
GO:0002011	biolink:NamedThing	morphogenesis of an epithelial sheet	The process in which the anatomical structures of an epithelial sheet are generated and organized. An epithelial sheet is a flat surface consisting of closely packed epithelial cells.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0061968	biolink:NamedThing	maintenance of left/right asymmetry	The organization process that preserves the asymmetry in an organism's body plan or part of an organism with respect to the left and right halves.	tmpzr1t_l9r_go_relaxed.owl								dph	2018-02-12T16:38:47Z					biological_process											owl:Class	
GO:0006719	biolink:NamedThing	juvenile hormone catabolic process	The chemical reactions and pathways resulting in the breakdown of juvenile hormones, the three sesquiterpenoid derivatives that function to maintain the larval state of insects at molting and that may be required for other processes, e.g. oogenesis.	tmpzr1t_l9r_go_relaxed.owl	juvenile hormone breakdown|juvenile hormone catabolism|juvenile hormone degradation													biological_process											owl:Class	
GO:0046225	biolink:NamedThing	bacteriocin catabolic process	The chemical reactions and pathways resulting in the breakdown of a bacteriocin, any of a heterogeneous group of polypeptide antibiotics that are secreted by certain bacterial strains and are able to kill cells of other susceptible (frequently related) strains after adsorption at specific receptors on the cell surface. They include the colicins, and their mechanisms of action vary.	tmpzr1t_l9r_go_relaxed.owl	bacteriocin catabolism|bacteriocin breakdown|bacteriocin degradation													biological_process											owl:Class	
GO:0030652	biolink:NamedThing	peptide antibiotic catabolic process	The chemical reactions and pathways resulting in the breakdown of peptides with antibiotic activity.	tmpzr1t_l9r_go_relaxed.owl	peptide antibiotic breakdown|peptide antibiotic catabolism|peptide antibiotic degradation													biological_process											owl:Class	
GO:1901239	biolink:NamedThing	malonate(1-) transmembrane transporter activity	Enables the transfer of malonate(1-) from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	malonic acid uptake transmembrane transporter activity				RHEA:33115			al	2012-08-07T15:09:02Z			GO:1901549		molecular_function											owl:Class	
GO:0052717	biolink:NamedThing	tRNA-specific adenosine-34 deaminase activity	Catalysis of the reaction: adenosine-34 + H2O = inosine-34 + NH3, in a tRNA-Ala molecule.	tmpzr1t_l9r_go_relaxed.owl	tRNA(Ala)-A34 deaminase activity							ai	2011-08-12T11:48:54Z					molecular_function											owl:Class	
GO:0008251	biolink:NamedThing	tRNA-specific adenosine deaminase activity	Catalysis of the reaction: adenosine + H2O = inosine + NH3, in a tRNA molecule.	tmpzr1t_l9r_go_relaxed.owl	tRNA-adenosine deaminase activity				Reactome:R-HSA-6782311|Reactome:R-HSA-6782336									molecular_function											owl:Class	
GO:0031679	biolink:NamedThing	NADH dehydrogenase (plastoquinone) activity	Catalysis of the reaction: NADH + H+ + plastoquinone = NAD+ + plastoquinol.	tmpzr1t_l9r_go_relaxed.owl	NADH:plastoquinone reductase activity											GO:0030024		molecular_function											owl:Class	
GO:0003071	biolink:NamedThing	renal system process involved in regulation of systemic arterial blood pressure	Renal process that modulates the force with which blood travels through the circulatory system. The process is controlled by a balance of processes that increase pressure and decrease pressure.	tmpzr1t_l9r_go_relaxed.owl	renal control of blood pressure|renal regulation of systemic arterial blood pressure													biological_process											owl:Class	
GO:0099143	biolink:NamedThing	presynaptic actin cytoskeleton	The actin cytoskeleton that is part of a presynapse.	tmpzr1t_l9r_go_relaxed.owl								dos	2017-06-09T18:36:19Z					cellular_component											owl:Class	
GO:0015629	biolink:NamedThing	actin cytoskeleton	The part of the cytoskeleton (the internal framework of a cell) composed of actin and associated proteins. Includes actin cytoskeleton-associated complexes.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0018657	biolink:NamedThing	toluene 3-monooxygenase activity	Catalysis of the reaction: toluene + 1/2 O2 = 3-hydroxytoluene.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:TOLUENE-3-MONOOXYGENASE-RXN|UM-BBD_enzymeID:e0224|EC:1.14.13.-									molecular_function											owl:Class	
GO:1904854	biolink:NamedThing	proteasome core complex binding	Binding to a proteasome core complex.	tmpzr1t_l9r_go_relaxed.owl	20S core complex binding|macropain binding|20S proteasome binding|PA28gamma-20S proteasome binding							mah	2015-12-15T11:54:19Z					molecular_function											owl:Class	
GO:1902910	biolink:NamedThing	positive regulation of melanosome transport	Any process that activates or increases the frequency, rate or extent of melanosome transport.	tmpzr1t_l9r_go_relaxed.owl	upregulation of melanosome transport|activation of melanosome transport|up-regulation of melanosome transport|up regulation of melanosome transport							als	2014-04-17T11:40:34Z					biological_process											owl:Class	
GO:0014707	biolink:NamedThing	branchiomeric skeletal muscle development	The process whose specific outcome is the progression of the branchiomeric skeletal muscle over time, from its formation to the mature structure. The branchiomeric muscle is derived from cranial mesoderm and controls facial expression, pharyngeal and laryngeal function, operating the jaw. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle. Branchiomeric muscles of mammals correspond to the gill musculature of fish.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0097238	biolink:NamedThing	cellular response to methylglyoxal	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methylglyoxal stimulus. Methylglyoxal is a 2-oxoaldehyde derived from propanal.	tmpzr1t_l9r_go_relaxed.owl								pr	2012-02-02T12:26:35Z					biological_process											owl:Class	
GO:0034888	biolink:NamedThing	endosulfan monooxygenase I activity	Catalysis of the reaction: endosulfan + O2 + 2 H+ + 2 e- = endosulfan sulfate + H2O.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r1382									molecular_function											owl:Class	
GO:0060394	biolink:NamedThing	negative regulation of pathway-restricted SMAD protein phosphorylation	Any process that decreases the rate, frequency or extent of pathway-restricted SMAD protein phosphorylation. Pathway-restricted SMAD proteins and common-partner SMAD proteins are involved in the transforming growth factor beta receptor signaling pathways.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0030486	biolink:NamedThing	smooth muscle dense body	Electron-dense region associated with a smooth muscle contractile fiber.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0047759	biolink:NamedThing	butanal dehydrogenase activity	Catalysis of the reaction: butanal + CoA + NAD(P)+ = butanoyl-CoA + NAD(P)H + H+.	tmpzr1t_l9r_go_relaxed.owl	butanal:NAD(P)+ oxidoreductase (CoA-acylating)				MetaCyc:BUTANAL-DEHYDROGENASE-RXN|EC:1.2.1.57									molecular_function											owl:Class	
GO:1900561	biolink:NamedThing	dehydroaustinol metabolic process	The chemical reactions and pathways involving dehydroaustinol.	tmpzr1t_l9r_go_relaxed.owl	dehydroaustinol metabolism							di	2012-05-15T06:27:35Z					biological_process											owl:Class	
GO:1903513	biolink:NamedThing	endoplasmic reticulum to cytosol transport	The directed movement of substances from endoplasmic reticulum to cytosol.	tmpzr1t_l9r_go_relaxed.owl	ER to cytosol transport							rl	2014-10-02T11:24:34Z					biological_process											owl:Class	
GO:0060149	biolink:NamedThing	negative regulation of posttranscriptional gene silencing	Any process that decreases the frequency, rate or extent of the inactivation of gene expression by a posttranscriptional mechanism.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0060147	biolink:NamedThing	regulation of posttranscriptional gene silencing	Any process that modulates the frequency, rate or extent of the inactivation of gene expression by a posttranscriptional mechanism.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1905055	biolink:NamedThing	calcium:cation antiporter activity involved in regulation of presynaptic cytosolic calcium ion concentration	Any calcium:cation antiporter activity that is involved in regulation of presynaptic cytosolic calcium ion concentration.	tmpzr1t_l9r_go_relaxed.owl	calcium ion antiporter activity involved in regulation of presynaptic cytosolic calcium levels							dos	2016-03-17T14:35:35Z					molecular_function											owl:Class	
GO:0015368	biolink:NamedThing	calcium:cation antiporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Ca2+(in) + cation(out) = Ca2+(out) + cation(in).	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-425822									molecular_function											owl:Class	
GO:0018756	biolink:NamedThing	ammeline aminohydrolase activity	Catalysis of the reaction: ammeline + H2O = ammelide + NH3.	tmpzr1t_l9r_go_relaxed.owl					RHEA:26201|MetaCyc:RXN-8016									molecular_function											owl:Class	
GO:0008881	biolink:NamedThing	glutamate racemase activity	Catalysis of the reaction: L-glutamate = D-glutamate.	tmpzr1t_l9r_go_relaxed.owl					RHEA:12813|KEGG_REACTION:R00260|MetaCyc:GLUTRACE-RXN|EC:5.1.1.3									molecular_function											owl:Class	
GO:0047661	biolink:NamedThing	amino-acid racemase activity	Catalysis of the reaction: an L-amino acid = a D-amino acid.	tmpzr1t_l9r_go_relaxed.owl	L-amino acid racemase activity				RHEA:18317|EC:5.1.1.10|MetaCyc:AMINO-ACID-RACEMASE-RXN									molecular_function											owl:Class	
GO:0009718	biolink:NamedThing	anthocyanin-containing compound biosynthetic process	The chemical reactions and pathways resulting in the formation of anthocyanins, any member of a group of intensely colored soluble glycosides of anthocyanidins.	tmpzr1t_l9r_go_relaxed.owl	anthocyanin synthesis|anthocyanin biosynthetic process|anthocyanin formation|anthocyanin anabolism|anthocyanin biosynthesis													biological_process											owl:Class	
GO:0002757	biolink:NamedThing	immune response-activating signal transduction	The cascade of processes by which a signal interacts with a receptor, causing a change in the level or activity of a second messenger or other downstream target, and ultimately leading to activation or perpetuation of an immune response.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0000036	biolink:NamedThing	acyl carrier activity	Binding an acyl group and presenting it for processing or offloading to a cognate enzyme. Covalently binds the acyl group via a phosphopantetheine prosthetic group and mediates protein-protein interactions with the enzyme conferring specificity. The acyl carrier protein (ACP) presents substrates to enzymes involved in fatty acid biosynthesis or in polyketide secondary metabolite biosynthesis.	tmpzr1t_l9r_go_relaxed.owl	ACP phosphopantetheine attachment site binding involved in fatty acid biosynthetic process													molecular_function											owl:Class	
GO:0140414	biolink:NamedThing	phosphopantetheine-dependent carrier activity	Binding a substrate via a thioester at the terminal thiol of a covalentely linked phosphopantetheine prosthetic group and mediating protein-protein interactions with cognate enzymes for processing or offloading of the thiol-bound substrate.	tmpzr1t_l9r_go_relaxed.owl	carrier protein activity							pg	2020-01-14T16:15:04Z					molecular_function											owl:Class	
GO:0042929	biolink:NamedThing	ferrichrome transmembrane transporter activity	Enables the directed movement of a ferrichrome from one side of a membrane to the other. Ferrichromes are any of a group of growth-promoting Fe(III) chelates formed by various genera of microfungi. They are homodetic cyclic hexapeptides made up of a tripeptide of glycine (or other small neutral amino acids) and a tripeptide of an N'acyl-N4-hydroxy-L-ornithine.	tmpzr1t_l9r_go_relaxed.owl	ferrichrome transporter activity													molecular_function											owl:Class	
GO:0015603	biolink:NamedThing	iron chelate transmembrane transporter activity	Enables the transfer of an iron chelate from one side of a membrane to the other. An iron chelate is a heterocyclic compound having a metal ion attached by coordinate bonds to at least two nonmetal ions.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:2000501	biolink:NamedThing	regulation of natural killer cell chemotaxis	Any process that modulates the frequency, rate or extent of natural killer cell chemotaxis.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-03-21T10:09:23Z					biological_process											owl:Class	
GO:0042850	biolink:NamedThing	L-sorbose catabolic process	The chemical reactions and pathways resulting in the breakdown of L-sorbose, the L-enantiomer of the ketohexose xylo-2-hexulose.	tmpzr1t_l9r_go_relaxed.owl	L-sorbose breakdown|L-sorbose degradation|L-sorbose catabolism													biological_process											owl:Class	
GO:0019312	biolink:NamedThing	L-sorbose metabolic process	The chemical reactions and pathways involving sorbose, the L-enantiomer of the ketohexose xylo-2-hexulose. L-sorbose is formed by bacterial oxidation of sorbitol.	tmpzr1t_l9r_go_relaxed.owl	L-sorbose metabolism				MetaCyc:P302-PWY									biological_process											owl:Class	
GO:0051667	biolink:NamedThing	establishment of plastid localization	The directed movement of a plastid to a specific location in the cell.	tmpzr1t_l9r_go_relaxed.owl	establishment of plastid localisation													biological_process											owl:Class	
GO:0004454	biolink:NamedThing	ketohexokinase activity	Catalysis of the reaction: ATP + D-fructose = ADP + D-fructose 1-phosphate.	tmpzr1t_l9r_go_relaxed.owl	ATP:D-fructose 1-phosphotransferase activity|ketohexokinase (phosphorylating)|hepatic fructokinase activity				Reactome:R-HSA-5656459|RHEA:18145|EC:2.7.1.3|Reactome:R-HSA-70333|MetaCyc:KETOHEXOKINASE-RXN									molecular_function											owl:Class	
GO:0005314	biolink:NamedThing	high-affinity glutamate transmembrane transporter activity	Enables the transfer of glutamate from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.	tmpzr1t_l9r_go_relaxed.owl	high-affinity glutamate transporter activity				Reactome:R-HSA-5625015|Reactome:R-HSA-5625029|Reactome:R-HSA-428015|Reactome:R-HSA-210404									molecular_function											owl:Class	
GO:0015501	biolink:NamedThing	glutamate:sodium symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glutamate(out) + Na+(out) = glutamate(in) + Na+(in).	tmpzr1t_l9r_go_relaxed.owl	sodium/excitatory glutamate cotransporter activity|sodium/excitatory glutamate symporter activity				RHEA:29031							GO:0008027		molecular_function											owl:Class	
GO:0014833	biolink:NamedThing	skeletal muscle satellite stem cell asymmetric division	The asymmetric division of a skeletal muscle satellite stem cell to produce two daughter cells, one of which is destined to differentiate and the other to be a quiescent cell that restocks the satellite cell pool.	tmpzr1t_l9r_go_relaxed.owl	satellite cell asymmetric division													biological_process											owl:Class	
GO:0048103	biolink:NamedThing	somatic stem cell division	The self-renewing division of a somatic stem cell, a stem cell that can give rise to cell types of the body other than those of the germ-line.	tmpzr1t_l9r_go_relaxed.owl	somatic stem cell renewal													biological_process											owl:Class	
GO:1904665	biolink:NamedThing	positive regulation of N-terminal peptidyl-methionine acetylation	Any process that activates or increases the frequency, rate or extent of N-terminal peptidyl-methionine acetylation.	tmpzr1t_l9r_go_relaxed.owl								vw	2015-09-07T19:19:02Z					biological_process											owl:Class	
GO:0102882	biolink:NamedThing	beta-acoradiene synthase activity	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate <=> beta-acoradiene + diphosphoric acid.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-8423									molecular_function											owl:Class	
GO:1900704	biolink:NamedThing	regulation of siderophore biosynthetic process	Any process that modulates the frequency, rate or extent of siderophore biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of siderophore synthesis|regulation of siderophore biosynthetic process, peptide formation|regulation of siderophore biosynthetic process, peptide modification|regulation of siderophore formation|regulation of siderochrome biosynthesis|regulation of siderophore biosynthesis|regulation of siderochrome biosynthetic process|regulation of siderophore anabolism							di	2012-05-22T04:59:28Z					biological_process											owl:Class	
GO:0035430	biolink:NamedThing	regulation of gluconate transmembrane transport	Any process that modulates the frequency, rate or extent of the directed movement of a gluconate across a membrane by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	regulation of gluconate transport|regulation of gluconate membrane transport							bf	2010-04-08T10:37:18Z			GO:0032893		biological_process											owl:Class	
GO:0046312	biolink:NamedThing	phosphoarginine biosynthetic process	The chemical reactions and pathways resulting in the formation of phosphoarginine, a phosphorylated derivative of the amino acid arginine.	tmpzr1t_l9r_go_relaxed.owl	phosphoarginine formation|phosphoarginine biosynthesis|phosphoarginine synthesis|phosphoarginine anabolism													biological_process											owl:Class	
GO:0006604	biolink:NamedThing	phosphoarginine metabolic process	The chemical reactions and pathways involving phosphoarginine, a phosphagen of L-arginine with phosphoric acid containing the phosphoamide bond. It is a source of energy in the contraction of muscle in invertebrates, corresponding to phosphocreatine in the muscles of vertebrates.	tmpzr1t_l9r_go_relaxed.owl	phosphoarginine metabolism													biological_process											owl:Class	
GO:0070504	biolink:NamedThing	selenium-containing prosthetic group biosynthetic process	The chemical reactions and pathways resulting in the formation of a prosthetic group that contains selenium, as in the selenium-dependent molybdenum hydroxylases. The selenium atom in the prosthetic group is required for enzymatic function but is labile to a variety of treatments.	tmpzr1t_l9r_go_relaxed.owl	selenium-containing prosthetic group synthesis|selenium-containing prosthetic group formation|selenium-containing prosthetic group biosynthesis|selenium-containing prosthetic group anabolism													biological_process											owl:Class	
GO:0051191	biolink:NamedThing	prosthetic group biosynthetic process	The chemical reactions and pathways resulting in the formation of a prosthetic group, the non-amino acid portion of certain protein molecules. Prosthetic groups may be inorganic or organic and are usually required for the biological activity of the protein.	tmpzr1t_l9r_go_relaxed.owl	prosthetic group formation|prosthetic group biosynthesis|coenzyme and prosthetic group biosynthesis|prosthetic group synthesis|prosthetic group anabolism|coenzyme and prosthetic group biosynthetic process													biological_process											owl:Class	
GO:0045344	biolink:NamedThing	negative regulation of MHC class I biosynthetic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of MHC class I.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of MHC class I synthesis|down-regulation of MHC class I biosynthetic process|negative regulation of MHC class I anabolism|downregulation of MHC class I biosynthetic process|negative regulation of MHC class I formation|negative regulation of major histocompatibility complex class I biosynthetic process|negative regulation of MHC class I biosynthesis|down regulation of MHC class I biosynthetic process|inhibition of MHC class I biosynthetic process|negative regulation of major histocompatibility complex class I biosynthesis													biological_process											owl:Class	
GO:0035089	biolink:NamedThing	establishment of apical/basal cell polarity	The specification and formation of the polarity of a cell along its apical/basal axis.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0061162	biolink:NamedThing	establishment of monopolar cell polarity	The specification and formation of monopolar intracellular organization or cell growth patterns. Monopolar cell organization is directional organization along an axis.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-06-23T09:30:59Z					biological_process											owl:Class	
GO:0019266	biolink:NamedThing	asparagine biosynthetic process from oxaloacetate	The chemical reactions and pathways resulting in the formation of asparagine from other compounds, including oxaloacetate.	tmpzr1t_l9r_go_relaxed.owl	asparagine synthesis from oxaloacetate|asparagine anabolism from oxaloacetate|asparagine formation from oxaloacetate				MetaCyc:ASPARAGINE-BIOSYNTHESIS									biological_process											owl:Class	
GO:0033385	biolink:NamedThing	geranylgeranyl diphosphate metabolic process	The chemical reactions and pathways involving geranylgeranyl diphosphate, a polyprenol compound involved in the biosynthesis of a variety of terpenoids including chlorophylls, carotenoids, tocopherols, plastoquinones, and the plant hormones gibberellins.	tmpzr1t_l9r_go_relaxed.owl	geranylgeranyldiphosphate metabolic process|geranylgeranyl diphosphate metabolism													biological_process											owl:Class	
GO:0098968	biolink:NamedThing	neurotransmitter receptor transport postsynaptic membrane to endosome	Vesicle-mediated transport of a neurotransmitter receptor complex from the postsynaptic membrane to the postsynaptic early endosome.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0052846	biolink:NamedThing	inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity	Catalysis of the reaction: 1,5-bisdiphosphoinositol-1D-myo-inositol 2,3,4,6-tetrakisphosphate + H2O = 1-diphospho-1D-myo-inositol 1,2,3,4,6-pentakisphosphate + phosphate + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-10965			ai	2011-12-05T11:02:23Z					molecular_function											owl:Class	
GO:0120222	biolink:NamedThing	regulation of blastocyst development	Any process that modulates the frequency, rate or extent of blastocyst development.	tmpzr1t_l9r_go_relaxed.owl								krc	2020-02-17T19:59:20Z					biological_process											owl:Class	
GO:1900862	biolink:NamedThing	negative regulation of cordyol C biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of cordyol C biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of cordyol C biosynthetic process|downregulation of cordyol C biosynthetic process|down regulation of cordyol C biosynthetic process							di	2012-06-07T01:56:38Z					biological_process											owl:Class	
GO:0140164	biolink:NamedThing	Golgi transport complex binding	Binding to a Golgi transport complex, a multisubunit tethering complex of the CATCHR family.	tmpzr1t_l9r_go_relaxed.owl	COG complex binding							pg	2018-02-08T11:49:38Z					molecular_function											owl:Class	
GO:0019292	biolink:NamedThing	tyrosine biosynthetic process from chorismate via 4-hydroxyphenylpyruvate	The chemical reactions and pathways resulting in the formation of tyrosine from other compounds, including chorismate, via the intermediate 4-hydroxyphenylpyruvate.	tmpzr1t_l9r_go_relaxed.owl	tyrosine synthesis from chorismate via 4-hydroxyphenylpyruvate|tyrosine anabolism from chorismate via 4-hydroxyphenylpyruvate|tyrosine biosynthetic process from chorismate via p-hydroxyphenylpyruvate|tyrosine formation from chorismate via 4-hydroxyphenylpyruvate				MetaCyc:TYRSYN									biological_process											owl:Class	
GO:0046417	biolink:NamedThing	chorismate metabolic process	The chemical reactions and pathways involving chorismate, the anion of (3R-trans)-3-((1-carboxyethenyl)oxy)-4-hydroxy-1,5-cyclohexadiene-1-carboxylic acid.	tmpzr1t_l9r_go_relaxed.owl	chorismate metabolism													biological_process											owl:Class	
GO:1903682	biolink:NamedThing	negative regulation of epithelial cell-cell adhesion involved in epithelium migration	Any process that stops, prevents or reduces the frequency, rate or extent of epithelial cell-cell adhesion involved in epithelium migration.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of epithelial cell-cell adhesion involved in epithelium migration|down regulation of epithelial cell-cell adhesion involved in epithelium migration|inhibition of epithelial cell-cell adhesion involved in epithelium migration|downregulation of epithelial cell-cell adhesion involved in epithelium migration							als	2014-12-01T13:25:14Z					biological_process											owl:Class	
GO:1900753	biolink:NamedThing	doxorubicin transport	The directed movement of a doxorubicin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	doxorubicine transport|(1S,3S)-3-glycoloyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranoside transport|Adriamycin transport|(1S,3S)-3,5,12-trihydroxy-3-(hydroxyacetyl)-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranoside transport|(8S-cis)-10-((3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-5,12-naphthacenedione transport|doxorubicinum transport|14-hydroxydaunorubicine transport|14-hydroxydaunomycin transport							jl	2012-05-29T02:50:43Z					biological_process											owl:Class	
GO:0042853	biolink:NamedThing	L-alanine catabolic process	The chemical reactions and pathways resulting in the breakdown of L-alanine, the L-enantiomer of 2-aminopropanoic acid, i.e. (2S)-2-aminopropanoic acid.	tmpzr1t_l9r_go_relaxed.owl	L-alanine degradation|L-alanine catabolism|L-alanine breakdown													biological_process											owl:Class	
GO:0005291	biolink:NamedThing	high-affinity L-histidine transmembrane transporter activity	Enables the transfer of L-histidine from one side of a membrane to the other. L-histidine is 2-amino-3-(1H-imidazol-4-yl)propanoic acid. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.	tmpzr1t_l9r_go_relaxed.owl	high affinity L-histidine transmembrane transporter activity|high affinity histidine permease activity													molecular_function											owl:Class	
GO:0005287	biolink:NamedThing	high-affinity basic amino acid transmembrane transporter activity	Enables the transfer of basic amino acids from one side of a membrane to the other. Acidic amino acids have a pH above 7. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.	tmpzr1t_l9r_go_relaxed.owl	high affinity basic amino acid transmembrane transporter activity|high-affinity basic amino acid transporter activity													molecular_function											owl:Class	
GO:0002154	biolink:NamedThing	thyroid hormone mediated signaling pathway	A series of molecular signals mediated by the detection of a thyroid hormone.	tmpzr1t_l9r_go_relaxed.owl	thyroid hormone mediated signalling pathway							hjd	2009-11-19T12:36:29Z					biological_process											owl:Class	
GO:1902062	biolink:NamedThing	betaine aldehyde catabolic process	The chemical reactions and pathways resulting in the breakdown of betaine aldehyde.	tmpzr1t_l9r_go_relaxed.owl	betaine aldehyde degradation|betaine aldehyde catabolism|betaine aldehyde breakdown							di	2013-04-16T12:07:12Z					biological_process											owl:Class	
GO:0002692	biolink:NamedThing	negative regulation of cellular extravasation	Any process that stops, prevents, or reduces the frequency, rate, or extent of cellular extravasation.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of cellular extravasation|down regulation of cellular extravasation|inhibition of cellular extravasation|downregulation of cellular extravasation													biological_process											owl:Class	
GO:0002686	biolink:NamedThing	negative regulation of leukocyte migration	Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte migration.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of leukocyte migration|negative regulation of leucocyte migration|inhibition of leukocyte migration|downregulation of leukocyte migration|down regulation of leukocyte migration|negative regulation of immune cell migration													biological_process											owl:Class	
GO:1905686	biolink:NamedThing	positive regulation of plasma membrane repair	Any process that activates or increases the frequency, rate or extent of plasma membrane repair.	tmpzr1t_l9r_go_relaxed.owl	activation of plasma membrane repair|upregulation of plasma membrane repair|up regulation of plasma membrane repair|up-regulation of plasma membrane repair							bhm	2016-11-14T10:30:46Z					biological_process											owl:Class	
GO:0097516	biolink:NamedThing	microvillar actin bundle	A parallel bundle of actin filaments at the core of a microvillus.	tmpzr1t_l9r_go_relaxed.owl								pr	2013-10-16T15:12:13Z					cellular_component											owl:Class	
GO:0047851	biolink:NamedThing	dicarboxylate-CoA ligase activity	Catalysis of the reaction: ATP + an omega-dicarboxylic acid + CoASH= AMP + diphosphate + an omega-carboxyacyl-CoA.	tmpzr1t_l9r_go_relaxed.owl	carboxylyl-CoA synthetase activity|omega-dicarboxylate:CoA ligase (AMP-forming)				RHEA:14289|EC:6.2.1.23|MetaCyc:DICARBOXYLATE--COA-LIGASE-RXN									molecular_function											owl:Class	
GO:1904947	biolink:NamedThing	folate import into mitochondrion	The process in which folic acid is transported from the cytosol into the mitochondrial matrix.	tmpzr1t_l9r_go_relaxed.owl	folic acid import into mitochondrion							rph	2016-02-03T12:10:14Z					biological_process											owl:Class	
GO:0033750	biolink:NamedThing	ribosome localization	A process in which a ribosome is transported to, and/or maintained in, a specific location.	tmpzr1t_l9r_go_relaxed.owl	ribosome localisation|establishment of ribosome localisation|establishment of ribosome localization											GO:0033753		biological_process											owl:Class	
GO:0150138	biolink:NamedThing	negative regulation of interleukin-37 production	Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-37 production.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of interleukin-37 biosynthetic process							bc	2019-12-08T08:45:29Z					biological_process											owl:Class	
GO:0002024	biolink:NamedThing	diet induced thermogenesis	The process that results in increased metabolic rate in tissues of an organism. It is triggered by the detection of dietary excess. This process is achieved via signalling in the sympathetic nervous system.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1990845	biolink:NamedThing	adaptive thermogenesis	The regulated production of heat in response to short term environmental changes, such as stress, diet or reduced temperature.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-08-31T18:19:49Z					biological_process											owl:Class	
GO:0008214	biolink:NamedThing	protein dealkylation	The removal of an alkyl group from a protein amino acid. Alkyl groups are derived from alkanes by removal of one hydrogen atom.	tmpzr1t_l9r_go_relaxed.owl	protein amino acid dealkylation													biological_process											owl:Class	
GO:1901250	biolink:NamedThing	negative regulation of lung goblet cell differentiation	Any process that stops, prevents or reduces the frequency, rate or extent of lung goblet cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of pulmonary goblet cell differentiation|down regulation of pulmonary goblet cell differentiation|inhibition of lung goblet cell differentiation|down regulation of lung goblet cell differentiation|downregulation of pulmonary goblet cell differentiation|inhibition of pulmonary goblet cell differentiation|negative regulation of pulmonary goblet cell differentiation|down-regulation of lung goblet cell differentiation|downregulation of lung goblet cell differentiation							vk	2012-08-08T08:59:36Z					biological_process											owl:Class	
GO:0043122	biolink:NamedThing	regulation of I-kappaB kinase/NF-kappaB signaling	Any process that modulates I-kappaB kinase/NF-kappaB signaling.	tmpzr1t_l9r_go_relaxed.owl	regulation of I-kappaB kinase/NF-kappaB cascade													biological_process											owl:Class	
GO:0106314	biolink:NamedThing	nitrite reductase NADPH activity	Catalysis of the reaction: ammonium hydroxide + 3 NADP+ + H2O = nitrite + 3 NADPH + 3 H+.	tmpzr1t_l9r_go_relaxed.owl					RHEA:24632			hjd	2020-09-23T14:28:27Z					molecular_function											owl:Class	
GO:0070201	biolink:NamedThing	regulation of establishment of protein localization	Any process that modulates the frequency, rate or extent of the directed movement of a protein to a specific location.	tmpzr1t_l9r_go_relaxed.owl	regulation of establishment of protein localisation													biological_process											owl:Class	
GO:0051644	biolink:NamedThing	plastid localization	Any process in which a plastid is transported to, and/or maintained in, a specific location within the cell.	tmpzr1t_l9r_go_relaxed.owl	establishment and maintenance of plastid localization|plastid localisation													biological_process											owl:Class	
GO:1990312	biolink:NamedThing	type-II cohesin domain binding	Binding to a type-II cohesin domain of a protein. Type-II cohesin domain is the binding partner of type-II dockerin domain.	tmpzr1t_l9r_go_relaxed.owl								tt	2014-03-07T04:51:07Z					molecular_function											owl:Class	
GO:0035775	biolink:NamedThing	pronephric glomerulus morphogenesis	The process in which the anatomical structures of the pronephric glomerulus are generated and organized. The pronephric glomerulus is part of the pronephric nephron and is restricted to one body segment.	tmpzr1t_l9r_go_relaxed.owl						This term is intended for annotation of fish and other organisms which contain a glomerulus as part of the pronephric nephron. It should not be used for annotation of Xenopus, which contains a pronephric glomus rather than a glomerulus.		bf	2011-04-04T10:59:28Z					biological_process											owl:Class	
GO:0072102	biolink:NamedThing	glomerulus morphogenesis	The process in which the anatomical structures of the glomerulus are generated and organized. The glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-02-10T02:32:09Z					biological_process											owl:Class	
GO:0047024	biolink:NamedThing	5alpha-androstane-3beta,17beta-diol dehydrogenase activity	Catalysis of the reaction: 5alpha-androstane-3beta,17beta-diol + NADP(+) = 17beta-hydroxy-5alpha-androstan-3-one + H(+) + NADPH.	tmpzr1t_l9r_go_relaxed.owl	3beta(or 20alpha)-hydroxysteroid:NADP+ oxidoreductase activity|dehydrogenase, 3beta,20alpha-hydroxy steroid|progesterone reductase activity|3-beta(or 20-alpha)-hydroxysteroid dehydrogenase activity|3beta,20alpha-hydroxysteroid oxidoreductase activity|3-beta-HSD activity|3beta(or 20alpha)-hydroxysteroid dehydrogenase activity				RHEA:16297|MetaCyc:1.1.1.210-RXN|KEGG_REACTION:R04344|EC:1.1.1.210									molecular_function											owl:Class	
GO:0048742	biolink:NamedThing	regulation of skeletal muscle fiber development	Any process that modulates the frequency, rate or extent of skeletal muscle fiber development. Muscle fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast.	tmpzr1t_l9r_go_relaxed.owl	regulation of skeletal myofibre development|regulation of skeletal myofiber development|regulation of skeletal muscle fibre development													biological_process											owl:Class	
GO:0050312	biolink:NamedThing	sulfoacetaldehyde lyase activity	Catalysis of the reaction: 2-sulfoacetaldehyde + H2O = acetate + sulfite.	tmpzr1t_l9r_go_relaxed.owl	sulphoacetaldehyde lyase activity				EC:4.4.1.-	Note that EC:4.4.1.12 was deleted from EC as the reaction is performed by sulfoacetaldehyde acetyltransferase (EC:2.3.3.15).								molecular_function											owl:Class	
GO:0072508	biolink:NamedThing	trivalent inorganic cation homeostasis	Any process involved in the maintenance of an internal steady state of trivalent cations within an organism or cell.	tmpzr1t_l9r_go_relaxed.owl						Note that this term was split from 'di-, tri-valent inorganic cation homeostasis ; GO:0055066' (sibling term 'divalent inorganic cation homeostasis' ; GO:0072507').		mah	2010-12-16T03:26:40Z					biological_process											owl:Class	
GO:0033990	biolink:NamedThing	ectoine synthase activity	Catalysis of the reaction: N(4)-acetyl-L-2,4-diaminobutyrate = ectoine + H(2)O.	tmpzr1t_l9r_go_relaxed.owl	N-acetyldiaminobutanoate dehydratase activity|EctC|N-acetyldiaminobutyrate dehydratase activity|4-N-acetyl-L-2,4-diaminobutanoate hydro-lyase (L-ectoine-forming) activity|N4-acetyl-L-2,4-diaminobutanoate hydro-lyase (L-ectoine-forming) activity|L-ectoine synthase activity				EC:4.2.1.108|RHEA:17281|KEGG_REACTION:R06979|MetaCyc:R103-RXN									molecular_function											owl:Class	
GO:0070958	biolink:NamedThing	negative regulation of neutrophil mediated killing of gram-positive bacterium	Any process that decreases the frequency, rate or extent of the directed killing of a gram-positive bacterium by a neutrophil.	tmpzr1t_l9r_go_relaxed.owl	inhibition of neutrophil mediated killing of gram-positive bacterium|downregulation of neutrophil mediated killing of gram-positive bacterium|down-regulation of neutrophil mediated killing of gram-positive bacterium|down regulation of neutrophil mediated killing of gram-positive bacterium							mah	2009-10-01T02:20:17Z					biological_process											owl:Class	
GO:0070956	biolink:NamedThing	negative regulation of neutrophil mediated killing of bacterium	Any process that decreases the frequency, rate or extent of the directed killing of a bacterium by a neutrophil.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of neutrophil mediated killing of bacterium|down regulation of neutrophil mediated killing of bacterium|inhibition of neutrophil mediated killing of bacterium|downregulation of neutrophil mediated killing of bacterium							mah	2009-10-01T02:20:17Z					biological_process											owl:Class	
GO:0090483	biolink:NamedThing	phosphatidylglycerol-phosphatidylethanolamine phosphatidyltransferase activity	Catalysis of the reaction: phosphatidylglycerol + phosphatidylethanolamine = cardiolipin + ethanolamine.	tmpzr1t_l9r_go_relaxed.owl	cardiolipin synthase							tb	2012-10-03T14:20:05Z					molecular_function											owl:Class	
GO:0099521	biolink:NamedThing	ATPase coupled ion transmembrane transporter activity involved in regulation of presynaptic membrane potential	Any ATPase coupled ion transmembrane transporter activity, occurring in the presynaptic membrane, that is involved in regulation of presynaptic membrane potential.	tmpzr1t_l9r_go_relaxed.owl	ATPase coupled ion transmembrane transporter activity involved in regulation of pre-synaptic membrane potential|ATPase-coupled ion transmembrane transporter activity involved in regulation of presynaptic membrane potential													molecular_function											owl:Class	
GO:0042625	biolink:NamedThing	ATPase-coupled ion transmembrane transporter activity	Enables the transfer of an ion from one side of a membrane to the other, driven by the reaction: ATP + H2O = ADP + phosphate.	tmpzr1t_l9r_go_relaxed.owl	ATPase coupled ion transmembrane transporter activity|ATP-dependent ion transmembrane transporter activity|ATPase activity, coupled to transmembrane movement of ions													molecular_function											owl:Class	
GO:0044554	biolink:NamedThing	modulation of heart rate in other organism	Any process that modulates the frequency or rate of heart contraction of another organism.	tmpzr1t_l9r_go_relaxed.owl	regulation of heart rate in other organism							jl	2012-03-29T02:59:43Z					biological_process											owl:Class	
GO:0019526	biolink:NamedThing	pentitol biosynthetic process	The chemical reactions and pathways resulting in the formation of pentitols, any alditol with a chain of five carbon atoms in the molecule.	tmpzr1t_l9r_go_relaxed.owl	pentitol synthesis|pentitol anabolism|pentitol biosynthesis|pentitol formation													biological_process											owl:Class	
GO:0019519	biolink:NamedThing	pentitol metabolic process	The chemical reactions and pathways involving pentitols, any alditol with a chain of five carbon atoms in the molecule.	tmpzr1t_l9r_go_relaxed.owl	pentitol metabolism													biological_process											owl:Class	
GO:0002916	biolink:NamedThing	positive regulation of central B cell anergy	Any process that activates or increases the frequency, rate, or extent of central B cell anergy.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of central B cell anergy|upregulation of central B cell anergy|up regulation of central B cell anergy|activation of central B cell anergy|stimulation of central B cell anergy													biological_process											owl:Class	
GO:2000646	biolink:NamedThing	positive regulation of receptor catabolic process	Any process that activates or increases the frequency, rate or extent of receptor catabolic process.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of receptor catabolism|positive regulation of receptor degradation|positive regulation of receptor breakdown							vk	2011-04-21T11:20:25Z					biological_process											owl:Class	
GO:0015900	biolink:NamedThing	benomyl transport	The directed movement of benomyl into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Benomyl, methyl 1-(butylcarbamoyl)-2-benzimidazolecarbamate, is a systemic agricultural fungicide used for control of certain fungal diseases of stone fruit.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0030992	biolink:NamedThing	intraciliary transport particle B	The larger subcomplex of the intraciliary transport particle; characterized complexes have molecular weights around 550 kDa.	tmpzr1t_l9r_go_relaxed.owl	intraflagellar transport particle B|IFT complex B|IFT B complex|intraflagellar transport complex B					Note that we deem cilia and microtubule-based flagella to be equivalent.								cellular_component											owl:Class	
GO:0050958	biolink:NamedThing	magnetoreception	The series of events required for an organism to receive a stimulus relating to a magnetic field, convert it to a molecular signal, and recognize and characterize the signal. Stimuli may be chemical, mechanical or electrical and interpreting these stimuli allows an organism to determine the orientation of a magnetic field. Magnetoreception also involves the perception of light; birds cannot orient without the presence of short wavelength (blue/green) light.	tmpzr1t_l9r_go_relaxed.owl	magnetoception|sensory perception of magnetic field				Wikipedia:Magnetoception									biological_process											owl:Class	
GO:0048629	biolink:NamedThing	trichome patterning	The regionalization process of establishing the non-random spatial arrangement of trichomes on the surface and margin of a leaf. Process involves signaling between adjacent epidermal cells that results in differentiation of some epidermal cells into trichomes.	tmpzr1t_l9r_go_relaxed.owl	trichome pattern biosynthesis|trichome pattern specification|trichome spacing|trichome pattern formation|trichome distribution													biological_process											owl:Class	
GO:0045168	biolink:NamedThing	cell-cell signaling involved in cell fate commitment	Signaling at long or short range between cells that results in the commitment of a cell to a certain fate.	tmpzr1t_l9r_go_relaxed.owl	cell-cell signalling during cell fate commitment|cell fate commitment, cell-cell signalling|cell fate commitment, cell-cell signaling|cell-cell signaling during in cell fate commitment|cell-cell signaling resulting in cell fate commitment|cell-cell signalling involved in cell fate specification|cell-cell signalling resulting in cell fate commitment													biological_process											owl:Class	
GO:0030262	biolink:NamedThing	apoptotic nuclear changes	Alterations undergone by nuclei at the molecular and morphological level as part of the execution phase of apoptosis.	tmpzr1t_l9r_go_relaxed.owl	apoptotic nuclear change													biological_process											owl:Class	
GO:0045197	biolink:NamedThing	establishment or maintenance of epithelial cell apical/basal polarity	Any cellular process that results in the specification, formation or maintenance of the apicobasal polarity of an epithelial cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1905511	biolink:NamedThing	positive regulation of myosin II filament assembly	Any process that activates or increases the frequency, rate or extent of myosin II filament assembly.	tmpzr1t_l9r_go_relaxed.owl	activation of myosin II polymerization|up regulation of myosin II filament assembly|up-regulation of myosin II filament assembly|activation of myosin II filament assembly|up-regulation of myosin II polymerization|upregulation of myosin II filament assembly|upregulation of myosin II polymerization|up regulation of myosin II polymerization|positive regulation of myosin II polymerization					positive regulation / down regulation of the formation of a bipolar filament composed of myosin II molecules		pf	2016-09-28T13:48:03Z					biological_process											owl:Class	
GO:0034422	biolink:NamedThing	aleurone grain lumen	The volume enclosed by the membrane of an aleurone grain.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0019638	biolink:NamedThing	6-hydroxycineole metabolic process	The chemical reactions and pathways involving 6-hydroxycineole (6-hydroxy-1,8-epoxy-p-menthane), a hydrocarbon with the formula C10H18O2.	tmpzr1t_l9r_go_relaxed.owl	6-endo-hydroxycineole metabolic process|hydroxycineol metabolism|6-hydroxycineole metabolism|6-endo-hydroxycineole metabolism|hydroxycineol metabolic process													biological_process											owl:Class	
GO:0052763	biolink:NamedThing	ulvan lyase activity	Catalysis of the cleavage of a carbon-oxygen bond in ulvan, a carbohydrate composed of a repeating structure of [->4)-beta-D-GlcA-(1,4)-alpha-L-Rha 3S-(1->4)-alpha-L-IdoA-(1->4)-alpha-L-Rha 3S-(1-]n. Continued digest of ulvan with an enzyme that can catalyze this reaction results in ulvanobiouronic acid A 3-sulfate [->4)-beta-D-GlcpA-(1->4)-alpha-L-Rhap 3-sulfate-(1-]n with 4-deoxy-L-threo-hex-4-enopyranosiduronic acid at the non-reducing end.	tmpzr1t_l9r_go_relaxed.owl								ai	2011-09-29T03:39:23Z					molecular_function											owl:Class	
GO:1905203	biolink:NamedThing	regulation of connective tissue replacement	Any process that modulates the frequency, rate or extent of connective tissue replacement.	tmpzr1t_l9r_go_relaxed.owl								bc	2016-05-17T09:54:18Z					biological_process											owl:Class	
GO:0052918	biolink:NamedThing	dol-P-Man:Man(8)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity	Catalysis of the reaction: alpha-D-man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-(alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-(alpha-D-Man-(1->6))-alpha-D-Man-(1->6))-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-diphosphodolichol + dolichyl D-mannosyl phosphate = H(+) + alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-(alpha-D-Man-(1->2)-alpha-D-Man-(1->6))-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-diphosphodolichol + dolichyl phosphate.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-5469|EC:2.4.1.261|KEGG_REACTION:R06261|RHEA:29539									molecular_function											owl:Class	
GO:0000026	biolink:NamedThing	alpha-1,2-mannosyltransferase activity	Catalysis of the transfer of a mannose residue to an oligosaccharide, forming an alpha-(1->2) linkage.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-4720478|Reactome:R-HSA-9035514|Reactome:R-HSA-4551297|Reactome:R-HSA-446216|Reactome:R-HSA-446187|Reactome:R-HSA-446215									molecular_function											owl:Class	
GO:0019191	biolink:NamedThing	cellobiose transmembrane transporter activity	Enables the transfer of cellobiose from one side of a membrane to the other. Cellobiose, or 4-O-beta-D-glucopyranosyl-D-glucose, is a disaccharide that represents the basic repeating unit of cellulose.	tmpzr1t_l9r_go_relaxed.owl	cellobiose permease activity											GO:0019190		molecular_function											owl:Class	
GO:0015154	biolink:NamedThing	disaccharide transmembrane transporter activity	Enables the transfer of disaccharide from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0002412	biolink:NamedThing	antigen transcytosis by M cells in mucosal-associated lymphoid tissue	The process of antigen transcytosis carried out by M cells in the mucosal-associated lymphoid tissue (MALT). Transcytosis is the process of the directed movement of endocytosed material through the cell and its exocytosis from the plasma membrane at the opposite side. M cells are specialized epithelia cells with a microfold structure that are adept at moving antigens from the gut lumen to antigen presenting cells in the MALT.	tmpzr1t_l9r_go_relaxed.owl	antigen transport by M cells in mucosal-associated lymphoid tissue|antigen transport by M cells in MALT|antigen transcytosis by M cells in MALT													biological_process											owl:Class	
GO:1903872	biolink:NamedThing	regulation of DNA recombinase mediator complex assembly	Any process that modulates the frequency, rate or extent of DNA recombinase mediator complex assembly.	tmpzr1t_l9r_go_relaxed.owl	regulation of DNA recombinase mediator complex formation							rb	2015-02-05T23:36:45Z					biological_process											owl:Class	
GO:0034824	biolink:NamedThing	citronellyl-CoA dehydrogenase activity	Catalysis of the reaction: citronellyl-CoA + NAD+ = cis-geranyl-CoA + NADH + H+.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r1159									molecular_function											owl:Class	
GO:0019051	biolink:NamedThing	induction by virus of host apoptotic process	The set of viral processes that induce an apoptotic process in infected host cells, facilitating release and spread of progeny virions.	tmpzr1t_l9r_go_relaxed.owl	induction of apoptosis in host by virus|induction by virus of host apoptotic programmed cell death|activation by virus of host apoptotic programmed cell death|activation by virus of host apoptosis|induction by virus of host apoptosis|activation of apoptosis in host by virus													biological_process											owl:Class	
GO:0060139	biolink:NamedThing	positive regulation of apoptotic process by virus	Any viral process that activates or increases the frequency, rate or extent of cell death by apoptotic process.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of apoptosis by virus													biological_process											owl:Class	
GO:2000898	biolink:NamedThing	regulation of glucomannan catabolic process	Any process that modulates the frequency, rate or extent of glucomannan catabolic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of glucomannan catabolism							tt	2011-07-29T01:13:16Z					biological_process											owl:Class	
GO:2000454	biolink:NamedThing	positive regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation	Any process that activates or increases the frequency, rate or extent of CD8-positive, alpha-beta cytotoxic T cell extravasation.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-03-04T10:45:52Z					biological_process											owl:Class	
GO:0071894	biolink:NamedThing	histone H2B conserved C-terminal lysine ubiquitination	A histone ubiquitination process in which a ubiquitin monomer is added to a conserved lysine residue in the C-terminus of histone H2B. The conserved lysine residue is K119 in fission yeast, K123 in budding yeast, or K120 in mammals.	tmpzr1t_l9r_go_relaxed.owl	budding yeast H2B K123 ubiquitination|mammalian H2B K120 ubiquitination|fission yeast H2B K119 ubiquitination							mah	2010-09-14T03:43:46Z					biological_process											owl:Class	
GO:1904572	biolink:NamedThing	negative regulation of mRNA binding	Any process that stops, prevents or reduces the frequency, rate or extent of mRNA binding.	tmpzr1t_l9r_go_relaxed.owl	downregulation of mRNA binding|down regulation of mRNA binding|inhibition of mRNA binding|down-regulation of mRNA binding							sl	2015-08-19T17:51:03Z					biological_process											owl:Class	
GO:0010791	biolink:NamedThing	DNA double-strand break processing involved in repair via synthesis-dependent strand annealing	The 5' to 3' exonucleolytic resection of the DNA at the site of the break to form a 3' single-strand DNA overhang that results in the repair of a double strand break via synthesis-dependent strand annealing.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0048326	biolink:NamedThing	positive regulation of axial mesodermal cell fate determination	Any process that activates or increases the frequency, rate or extent of axial mesoderm cell fate determination.	tmpzr1t_l9r_go_relaxed.owl	up regulation of axial mesodermal cell fate determination|upregulation of axial mesodermal cell fate determination|activation of axial mesodermal cell fate determination|stimulation of axial mesodermal cell fate determination|up-regulation of axial mesodermal cell fate determination													biological_process											owl:Class	
GO:0047187	biolink:NamedThing	deacetyl-[citrate-(pro-3S)-lyase] S-acetyltransferase activity	Catalysis of the reaction: deacetyl-[citrate-oxaloacetate-lyase ((pro-3S)-CH(2)COO(-)-acetate)] + S-acetylphosphopantetheine = [citrate oxaloacetate-lyase ((pro-3S)-CH(2)COO(-)-acetate)] + pantetheine 4'-phosphate.	tmpzr1t_l9r_go_relaxed.owl	deacetyl-citrate-(pro-3S)-lyase S-acetyltransferase activity|S-acetyl phosphopantetheine:deacetyl citrate lyase S-acetyltransferase activity|S-acetylphosphopantetheine:deacetyl-citrate-oxaloacetate-lyase((pro-3S)-CH2COO-rightacetate)S-acetyltransferase activity|deacetyl-citrate-(pro-3S)-lyase acetyltransferase activity				MetaCyc:2.3.1.49-RXN|EC:2.3.1.49|RHEA:20393									molecular_function											owl:Class	
GO:1990333	biolink:NamedThing	mitotic checkpoint complex, CDC20-MAD2 subcomplex	A protein complex involved in the spindle checkpoint, preventing the activation of the anaphase-promoting complex until all chromosomes are correctly attached in a bipolar fashion to the mitotic spindle. In budding yeast this complex consists of Mad2p and Cdc20p, and in mammalian cells it consists of MAD2 and CDC20.	tmpzr1t_l9r_go_relaxed.owl	CDC20-MAD2 complex					An example of this is cdc20 in Saccharomyces cerevisiae (P26309) in PMID:15879521 (inferred from direct assay).		bhm	2014-03-17T14:11:35Z					cellular_component											owl:Class	
GO:0032548	biolink:NamedThing	pyrimidine deoxyribonucleoside binding	Binding to a pyrimidine deoxyribonucleoside, a compound consisting of a pyrimidine base linked to deoxyribose.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0032546	biolink:NamedThing	deoxyribonucleoside binding	Binding to a deoxyribonucleoside, a compound consisting of a purine or pyrimidine nitrogenous base linked to deoxyribose.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0080047	biolink:NamedThing	GDP-L-galactose phosphorylase activity	Catalysis of the reaction: GDP-L-galactose + phosphate = L-galactose-1-P + GDP.	tmpzr1t_l9r_go_relaxed.owl					RHEA:27698|EC:2.7.7.69|MetaCyc:RXNQT-4141									molecular_function											owl:Class	
GO:0140027	biolink:NamedThing	contractile vacuole localization	The directed movement of the contractile vacuole to a specific location.	tmpzr1t_l9r_go_relaxed.owl	establishment of contractile vacuole localization	https://github.com/geneontology/go-ontology/issues/22182|https://github.com/geneontology/go-ontology/issues/13407						pg	2017-05-02T10:23:26Z					biological_process											owl:Class	
GO:1904474	biolink:NamedThing	cellular response to L-dopa	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-dopa stimulus.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-07-09T20:15:59Z					biological_process											owl:Class	
GO:1905645	biolink:NamedThing	negative regulation of FACT complex assembly	Any process that stops, prevents or reduces the frequency, rate or extent of FACT complex assembly.	tmpzr1t_l9r_go_relaxed.owl	inhibition of Facilitates chromatin transcription complex formation|downregulation of FACT complex assembly|down-regulation of Facilitates chromatin transcription complex assembly|down-regulation of Facilitates chromatin transcription complex formation|down-regulation of FACT complex assembly|down regulation of FACT complex formation|inhibition of FACT complex assembly|inhibition of Facilitates chromatin transcription complex assembly|down regulation of FACT complex assembly|down-regulation of FACT complex formation|negative regulation of Facilitates chromatin transcription complex assembly|negative regulation of Facilitates chromatin transcription complex formation|downregulation of Facilitates chromatin transcription complex formation|downregulation of Facilitates chromatin transcription complex assembly|downregulation of FACT complex formation|negative regulation of FACT complex formation|inhibition of FACT complex formation|down regulation of Facilitates chromatin transcription complex formation|down regulation of Facilitates chromatin transcription complex assembly							pga	2016-11-07T09:14:13Z					biological_process											owl:Class	
GO:1905644	biolink:NamedThing	regulation of FACT complex assembly	Any process that modulates the frequency, rate or extent of FACT complex assembly.	tmpzr1t_l9r_go_relaxed.owl	regulation of Facilitates chromatin transcription complex assembly|regulation of FACT complex formation|regulation of Facilitates chromatin transcription complex formation							pga	2016-11-07T09:14:06Z					biological_process											owl:Class	
GO:0050896	biolink:NamedThing	response to stimulus	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism.	tmpzr1t_l9r_go_relaxed.owl	physiological response to stimulus					Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.						GO:0051869		biological_process											owl:Class	
GO:1900757	biolink:NamedThing	regulation of D-amino-acid oxidase activity	Any process that modulates the frequency, rate or extent of D-amino-acid oxidase activity.	tmpzr1t_l9r_go_relaxed.owl	regulation of L-amino acid:O2 oxidoreductase activity|regulation of new yellow enzyme|regulation of D-amino-acid:oxygen oxidoreductase (deaminating)							pm	2012-05-31T11:23:45Z					biological_process											owl:Class	
GO:0001407	biolink:NamedThing	glycerophosphodiester transmembrane transport	The process in which a glycerophosphodiester is transported across a membrane. Glycerophosphodiesters are small molecules composed of glycerol-3-phosphate and an alcohol, for example, glycerophosphoinositol.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0043365	biolink:NamedThing	[formate-C-acetyltransferase]-activating enzyme activity	Catalysis of the reaction: S-adenosyl-L-methionine + dihydroflavodoxin + [formate C-acetyltransferase]-glycine = 5'-deoxyadenosine + L-methionine + flavodoxin semiquinone + [formate C-acetyltransferase]-glycin-2-yl radical.	tmpzr1t_l9r_go_relaxed.owl	formate acetyltransferase-glycine dihydroflavodoxin:S-adenosyl-L-methionine oxidoreductase (S-adenosyl-L-methionine cleaving) activity|formate-C-acetyltransferase-activating enzyme|PFL activase activity|pyruvate formate-lyase-activating enzyme|formate acetyltransferase activating enzyme activity|formate C-acetyltransferase-glycine dihydroflavodoxin:S-adenosyl-L-methionine oxidoreductase (S-adenosyl-L-methionine cleaving)|[pyruvate formate-lyase]-activating enzyme activity|PFL-glycine:S-adenosyl-L-methionine H transferase (flavodoxin-oxidizing, S-adenosyl-L-methionine-cleaving) activity	https://github.com/geneontology/go-ontology/issues/14190			MetaCyc:TDCEACT-RXN|RHEA:19225|EC:1.97.1.4							GO:0008862		molecular_function											owl:Class	
GO:0043364	biolink:NamedThing	glycyl-radical enzyme activating activity	Catalyzes the activation of an enzyme by generating an organic free radical on a glycine residue via a homolytic cleavage of S-adenosyl-L-methionine (SAM).	tmpzr1t_l9r_go_relaxed.owl	catalysis of free radical formation	https://github.com/geneontology/go-ontology/issues/14190			EC:1.97.1.-									molecular_function											owl:Class	
GO:1990309	biolink:NamedThing	type-II dockerin domain binding	Binding to a type-II dockerin domain of a protein. Type-II dockerin domain is the binding partner of type-II cohesin domain.	tmpzr1t_l9r_go_relaxed.owl								tt	2014-03-07T03:16:49Z					molecular_function											owl:Class	
GO:0048563	biolink:NamedThing	post-embryonic animal organ morphogenesis	Morphogenesis, during the post-embryonic phase, of an animal tissue or tissues that work together to perform a specific function or functions. Morphogenesis pertains to process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0015780	biolink:NamedThing	nucleotide-sugar transmembrane transport	The directed movement of nucleotide-sugars into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Nucleotide-sugars are any nucleotide in which the distal phosphoric residue of a nucleoside 5'-diphosphate is in glycosidic linkage with a monosaccharide or monosaccharide derivative.	tmpzr1t_l9r_go_relaxed.owl	nucleotide-sugar transport													biological_process											owl:Class	
GO:0006982	biolink:NamedThing	response to lipid hydroperoxide	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipid hydroperoxide stimulus. Lipid hydroperoxide is the highly reactive primary oxygenated products of polyunsaturated fatty acids.	tmpzr1t_l9r_go_relaxed.owl	response to LHPO													biological_process											owl:Class	
GO:0033194	biolink:NamedThing	response to hydroperoxide	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydroperoxide stimulus. Hydroperoxides are monosubstitution products of hydrogen peroxide, HOOH.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0032676	biolink:NamedThing	regulation of interleukin-7 production	Any process that modulates the frequency, rate, or extent of interleukin-7 production.	tmpzr1t_l9r_go_relaxed.owl	regulation of interleukin-7 biosynthetic process|regulation of IL-7 production|regulation of interleukin-7 secretion											GO:0045411|GO:0150112		biological_process											owl:Class	
GO:0045435	biolink:NamedThing	lycopene epsilon cyclase activity	Catalysis of the cyclization of an epsilon ring at one end of the lycopene molecule (psi, psi-carotene) to form delta-carotene (epsilon, psi-carotene).	tmpzr1t_l9r_go_relaxed.owl	lycopene cyclase													molecular_function											owl:Class	
GO:0018548	biolink:NamedThing	pentaerythritol trinitrate reductase activity	Catalysis of the reaction: pentaerythritol trinitrate + NADPH = NADP+ + nitrate + pentaerythritol dinitrate.	tmpzr1t_l9r_go_relaxed.owl	xenobiotic reductase activity				UM-BBD_reactionID:r0025|EC:1.6.99.1									molecular_function											owl:Class	
GO:0034986	biolink:NamedThing	iron chaperone activity	Directly binding to and delivering iron ions to a target protein.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0016530	biolink:NamedThing	metallochaperone activity	Binding to and delivering metal ions to a target protein.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1901371	biolink:NamedThing	regulation of leaf morphogenesis	Any process that modulates the frequency, rate or extent of leaf morphogenesis.	tmpzr1t_l9r_go_relaxed.owl								tb	2012-09-24T23:07:17Z					biological_process											owl:Class	
GO:0033167	biolink:NamedThing	ARC complex	A ribonucleoprotein complex that contains members of the Argonaute family of proteins, additional protein subunits, and duplex siRNA; required for heterochromatin assembly and siRNA generation. Possibly involved in the conversion of ds siRNA to ss siRNA.	tmpzr1t_l9r_go_relaxed.owl	argonaute siRNA chaperone complex													cellular_component											owl:Class	
GO:1904889	biolink:NamedThing	regulation of excitatory synapse assembly	Any process that modulates the frequency, rate or extent of excitatory synapse assembly.	tmpzr1t_l9r_go_relaxed.owl	regulation of excitatory synapse formation							bf	2016-01-07T14:35:53Z					biological_process											owl:Class	
GO:0006722	biolink:NamedThing	triterpenoid metabolic process	The chemical reactions and pathways involving triterpenoid compounds, terpenoids with six isoprene units.	tmpzr1t_l9r_go_relaxed.owl	triterpenoid metabolism|triterpene metabolism|triterpene metabolic process													biological_process											owl:Class	
GO:0060157	biolink:NamedThing	urinary bladder development	The process whose specific outcome is the progression of the urinary bladder over time, from its formation to the mature structure. The urinary bladder is an elastic, muscular sac situated in the anterior part of the pelvic cavity in which urine collects before excretion.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0008973	biolink:NamedThing	phosphopentomutase activity	Catalysis of the reaction: D-ribose 1-phosphate = D-ribose 5-phosphate.	tmpzr1t_l9r_go_relaxed.owl	deoxyribose phosphomutase activity|alpha-D-ribose 1,5-phosphomutase activity|alpha-D-glucose-1,6-bisphosphate:deoxy-D-ribose-1-phosphate phosphotransferase activity|phosphoribomutase activity|phosphodeoxyribomutase activity|D-ribose 1,5-phosphomutase activity|deoxyribomutase activity				EC:5.4.2.7|RHEA:18793|MetaCyc:PPENTOMUT-RXN|Reactome:R-HSA-8982667|Reactome:R-HSA-6787329									molecular_function											owl:Class	
GO:0120191	biolink:NamedThing	negative regulation of termination of RNA polymerase II transcription	Any process that stops, prevents or reduces the frequency, rate or extent of termination of RNA polymerase II transcription.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of transcription termination from Pol II promoter|downregulation of RNA 3'-end formation by RNA polymerase II|down regulation of transcription termination from Pol II promoter|down regulation of transcription termination from RNA polymerase II promoter|down regulation of termination of RNA polymerase II transcription|negative regulation of RNA polymerase II transcription termination|down regulation of RNA polymerase II transcription termination factor activity|negative regulation of RNA polymerase II transcription termination factor activity|down-regulation of RNA polymerase II transcription termination factor activity|repression of RNA polymerase II transcription termination|down-regulation of termination of RNA polymerase II transcription|downregulation of transcription termination from Pol II promoter|down-regulation of transcription termination from RNA polymerase II promoter|repression of transcription termination from Pol II promoter|down regulation of RNA polymerase II transcription termination|downregulation of RNA polymerase II transcription termination|repression of termination of RNA polymerase II transcription|negative regulation of RNA 3'-end formation by RNA polymerase II|repression of transcription termination from RNA polymerase II promoter|downregulation of RNA polymerase II transcription termination factor activity|down-regulation of RNA 3'-end formation by RNA polymerase II|downregulation of termination of RNA polymerase II transcription|negative regulation of transcription termination from RNA polymerase II promoter|down-regulation of RNA polymerase II transcription termination|repression of RNA polymerase II transcription termination factor activity|repression of RNA 3'-end formation by RNA polymerase II|down-regulation of transcription termination from Pol II promoter|down regulation of RNA 3'-end formation by RNA polymerase II|downregulation of transcription termination from RNA polymerase II promoter							krc	2018-07-18T15:43:40Z					biological_process											owl:Class	
GO:0140205	biolink:NamedThing	oligopeptide import across plasma membrane	The directed movement of an oligopeptide from outside of a cell, across the plasma membrane and into the cytosol.	tmpzr1t_l9r_go_relaxed.owl								pg	2018-02-22T15:48:21Z					biological_process											owl:Class	
GO:0070881	biolink:NamedThing	regulation of proline transport	Any process that modulates the frequency, rate or extent of proline transport.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-08-21T04:48:34Z					biological_process											owl:Class	
GO:0010522	biolink:NamedThing	regulation of calcium ion transport into cytosol	Any process that modulates the rate of the directed movement of calcium ions into the cytosol of a cell. The cytosol is that part of the cytoplasm that does not contain membranous or particulate subcellular components.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0009704	biolink:NamedThing	de-etiolation	The greening response of plants grown in the dark (etiolated) as a result of chloroplast biogenesis and the accumulation of chlorophyll.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0036257	biolink:NamedThing	multivesicular body organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a multivesicular body. A multivesicular body is a type of late endosome in which regions of the limiting endosomal membrane invaginate to form internal vesicles; membrane proteins that enter the internal vesicles are sequestered from the cytoplasm.	tmpzr1t_l9r_go_relaxed.owl	MVB organization							bf	2012-06-15T01:09:53Z					biological_process											owl:Class	
GO:0071655	biolink:NamedThing	regulation of granulocyte colony-stimulating factor production	Any process that modulates the frequency, rate, or extent of production of granulocyte colony-stimulating factor.	tmpzr1t_l9r_go_relaxed.owl	regulation of G-CSF production|regulation of filgrastim production|regulation of colony stimulating factor 3 (granulocyte) production|regulation of CSF3 production|regulation of granulocyte colony stimulating factor production|regulation of lenograstim production|regulation of pluripoietin production							mah	2010-02-12T10:41:14Z					biological_process											owl:Class	
GO:0072760	biolink:NamedThing	cellular response to GW 7647	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a GW 7647 stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2012-11-09T11:46:28Z					biological_process											owl:Class	
GO:0009126	biolink:NamedThing	purine nucleoside monophosphate metabolic process	The chemical reactions and pathways involving purine nucleoside monophosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with phosphate on the sugar.	tmpzr1t_l9r_go_relaxed.owl	purine nucleoside monophosphate metabolism													biological_process											owl:Class	
GO:1900103	biolink:NamedThing	positive regulation of endoplasmic reticulum unfolded protein response	Any process that activates or increases the frequency, rate or extent of endoplasmic reticulum unfolded protein response.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of erUPR|up regulation of endoplasmic reticulum unfolded protein response|positive regulation of erUPR|up-regulation of ER unfolded protein response|positive regulation of SREBP-mediated signalling pathway|upregulation of ER unfolded protein response|up regulation of ER unfolded protein response|upregulation of erUPR|upregulation of endoplasmic reticulum unfolded protein response|up-regulation of endoplasmic reticulum unfolded protein response|up regulation of erUPR|activation of ER unfolded protein response|activation of erUPR|up regulation of SREBP-mediated signalling pathway|up-regulation of SREBP-mediated signalling pathway|activation of SREBP-mediated signalling pathway|positive regulation of ER unfolded protein response|upregulation of SREBP-mediated signalling pathway|activation of endoplasmic reticulum unfolded protein response							ppm	2012-02-15T11:15:35Z					biological_process											owl:Class	
GO:0038109	biolink:NamedThing	Kit signaling pathway	A series of molecular signals that starts with the binding of stem cell factor to the tyrosine kinase receptor KIT on the surface of a cell, and ends with regulation of a downstream cellular process, e.g. transcription. Stem cell factor (KIT ligand) binding to the receptor Kit mediates receptor dimerization, activation of its intrinsic tyrosine kinase activity and autophosphorylation. The activated receptor then phosphorylates various substrates, thereby activating distinct signaling cascades within the cell that trigger a change in state or activity of the cell.	tmpzr1t_l9r_go_relaxed.owl	SCF signaling pathway|stem cell factor signaling pathway|Kit signalling pathway|stem cell factor receptor signaling pathway							bf	2012-03-22T10:09:48Z					biological_process											owl:Class	
GO:0035749	biolink:NamedThing	myelin sheath adaxonal region	The region of the myelin sheath nearest to the axon.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-03-23T10:17:42Z					cellular_component											owl:Class	
GO:0036221	biolink:NamedThing	UTP diphosphatase activity	Catalysis of the reaction: UTP + H2O = UMP + diphosphate.	tmpzr1t_l9r_go_relaxed.owl	uridine triphosphate pyrophosphohydrolase activity				KEGG_REACTION:R00662|RHEA:29395			bf	2012-05-08T01:47:59Z					molecular_function											owl:Class	
GO:0072547	biolink:NamedThing	tricoumaroylspermidine meta-hydroxylase activity	Catalysis of the reaction: tricoumaroyl spermidine + NADPH + O2 = dicoumaroyl monocaffeoyl spermidine + NADP+ + H2O.	tmpzr1t_l9r_go_relaxed.owl	tricoumaroyl spermidine meta-hydroxylase activity				MetaCyc:RXN-11260			mah	2011-01-25T02:49:37Z					molecular_function											owl:Class	
GO:0072533	biolink:NamedThing	tri-(coumaroyl or caffeoyl) spermidine meta-hydroxylase activity	Catalysis of the meta-hydroxylation of any of the three phenolic rings on tricoumaroyl spermidine or any of its mono- or dicaffeoyl spermidine derivatives.	tmpzr1t_l9r_go_relaxed.owl						Note that the overall reaction representing three successive executions of this activity is N1,N5,N10-tricoumaroyl spermidine + 3 NADPH + 3 O2 = N1,N5,N10-tricaffeoyl spermidine + 3 NADP+ + 3 H2O; this corresponds to the MetaCyc reaction RXN-11260 (http://biocyc.org/META/NEW-IMAGE?type=REACTION&object=RXN-11260).		mah	2011-01-12T02:03:07Z					molecular_function											owl:Class	
GO:0008720	biolink:NamedThing	D-lactate dehydrogenase activity	Catalysis of the reaction: (R)-lactate + NAD(+) = H(+) + NADH + pyruvate.	tmpzr1t_l9r_go_relaxed.owl	D-lactic acid dehydrogenase activity|D-lactic dehydrogenase activity				EC:1.1.1.28|KEGG_REACTION:R00704|MetaCyc:DLACTDEHYDROGNAD-RXN|RHEA:16369									molecular_function											owl:Class	
GO:0043323	biolink:NamedThing	positive regulation of natural killer cell degranulation	Any process that activates or increases the frequency, rate or extent of natural killer cell degranulation.	tmpzr1t_l9r_go_relaxed.owl	up regulation of natural killer cell degranulation|positive regulation of natural killer cell granule exocytosis|up-regulation of natural killer cell degranulation|stimulation of natural killer cell degranulation|activation of natural killer cell degranulation|upregulation of natural killer cell degranulation|positive regulation of NK cell degranulation|positive regulation of NK cell granule exocytosis													biological_process											owl:Class	
GO:0045954	biolink:NamedThing	positive regulation of natural killer cell mediated cytotoxicity	Any process that activates or increases the frequency, rate or extent of natural killer cell mediated cytotoxicity.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of natural killer cell mediated cell killing|positive regulation of NK cell mediated cytolysis|up-regulation of natural killer cell mediated cytotoxicity|positive regulation of NK cell mediated cytotoxicity|up regulation of natural killer cell mediated cytotoxicity|activation of natural killer cell mediated cytotoxicity|positive regulation of natural killer cell mediated cell death|upregulation of natural killer cell mediated cytotoxicity|stimulation of natural killer cell mediated cytotoxicity|positive regulation of natural killer cell mediated cytolysis|positive regulation of NK cell mediated cell killing|positive regulation of NK cell mediated cell death													biological_process											owl:Class	
GO:0010817	biolink:NamedThing	regulation of hormone levels	Any process that modulates the levels of hormone within an organism or a tissue. A hormone is any substance formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells in the same organism, upon which it has a specific regulatory action.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:2000211	biolink:NamedThing	regulation of glutamate metabolic process	Any process that modulates the frequency, rate or extent of glutamate metabolic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of glutamic acid metabolic process|regulation of glutamate metabolism|regulation of glutamic acid metabolism							mah	2010-11-03T02:43:51Z					biological_process											owl:Class	
GO:0018466	biolink:NamedThing	limonene-1,2-diol dehydrogenase activity	Catalysis of the reaction: (1S,2S,4R)-limonene-1,2-diol + DCPIP+ = DCPIPH + H+ + (1S,4R)-1-hydroxy-2-oxolimonene.	tmpzr1t_l9r_go_relaxed.owl					EC:1.1.99.-|UM-BBD_reactionID:r0735									molecular_function											owl:Class	
GO:1903439	biolink:NamedThing	calcitonin family receptor complex	A protein complex which is capable of calcitonin family receptor activity. Calcitonin family receptors may form dimers, trimers or tetramers; adrenomedullin and amylin receptors have only been observed as dimers so far.	tmpzr1t_l9r_go_relaxed.owl								pr	2014-09-16T13:25:11Z					cellular_component											owl:Class	
GO:0097683	biolink:NamedThing	dinoflagellate apex	The anterior most point of a dinoflagellate epicone.	tmpzr1t_l9r_go_relaxed.owl	apex					The term name refers to a taxonomic group to make the label unique with respect to similarly-named anatomical structures.		pr	2014-12-18T09:29:51Z					cellular_component											owl:Class	
GO:0099113	biolink:NamedThing	negative regulation of presynaptic cytosolic calcium concentration	Any process that decreases the concentration of calcium ions in the presynaptic cytosol.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0010571	biolink:NamedThing	positive regulation of nuclear cell cycle DNA replication	Any process that activates or increases the frequency, rate or extent of the DNA-dependent DNA replication that occurs in the nucleus of eukaryotic organisms as part of the cell cycle.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of DNA replication during S phase|positive regulation of DNA replication involved in S phase|positive regulation of DNA replication involved in S-phase													biological_process											owl:Class	
GO:1903187	biolink:NamedThing	negative regulation of vitellogenesis	Any process that stops, prevents or reduces the frequency, rate or extent of vitellogenesis.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of yolk production|inhibition of vitellogenesis|downregulation of vitellogenesis|down regulation of yolk production|down-regulation of vitellogenesis|downregulation of yolk production|inhibition of yolk production|down regulation of vitellogenesis|negative regulation of yolk production							mr	2014-07-14T19:28:06Z					biological_process											owl:Class	
GO:1903523	biolink:NamedThing	negative regulation of blood circulation	Any process that stops, prevents or reduces the frequency, rate or extent of blood circulation.	tmpzr1t_l9r_go_relaxed.owl	inhibition of blood circulation|down regulation of hemolymph circulation|negative regulation of hemolymph circulation|down-regulation of hemolymph circulation|downregulation of hemolymph circulation|down-regulation of blood circulation|inhibition of hemolymph circulation|downregulation of blood circulation|down regulation of blood circulation							mr	2014-10-06T18:39:05Z					biological_process											owl:Class	
GO:1900188	biolink:NamedThing	negative regulation of cell adhesion involved in single-species biofilm formation	Any process that stops, prevents or reduces the frequency, rate or extent of cell adhesion involved in single-species biofilm formation.	tmpzr1t_l9r_go_relaxed.owl	downregulation of cell adhesion involved in single-species biofilm formation|down-regulation of cell adhesion involved in single-species biofilm formation|down regulation of cell adhesion involved in single-species biofilm formation|downregulation of cell adhesion during single-species biofilm formation|down regulation of cell adhesion during single-species biofilm formation|inhibition of cell adhesion involved in single-species biofilm formation|inhibition of cell adhesion during single-species biofilm formation|negative regulation of cell adhesion during single-species biofilm formation|down-regulation of cell adhesion during single-species biofilm formation							di	2012-03-19T12:38:54Z					biological_process											owl:Class	
GO:1900274	biolink:NamedThing	regulation of phospholipase C activity	Any process that modulates the frequency, rate or extent of phospholipase C activity.	tmpzr1t_l9r_go_relaxed.owl	regulation of phosphatidase C|regulation of lecithinase C activity|regulation of lipophosphodiesterase C							rl	2012-04-04T01:19:00Z					biological_process											owl:Class	
GO:0035170	biolink:NamedThing	lymph gland crystal cell differentiation	The process in which a relatively unspecialized larval lymph gland-derived hemocyte precursor cell acquires the specialized features of a crystal cell. Crystal cells are a class of cells that contain crystalline inclusions and are involved in the melanization of pathogenic material in the hemolymph.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0042688	biolink:NamedThing	crystal cell differentiation	The process in which a hemocyte precursor cell acquires the characteristics of a crystal cell, a class of cells that contain crystalline inclusions and are involved in the melanization of pathogenic material in the hemolymph.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1904488	biolink:NamedThing	regulation of reactive oxygen species metabolic process by positive regulation of transcription from RNA polymerase II promoter	A positive regulation of transcription from RNA polymerase II promoter that results in regulation of reactive oxygen species metabolic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of reactive oxygen species metabolic process by upregulation of global transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolic process by activation of global transcription from RNA polymerase II promoter|regulation of ROS metabolic process by positive regulation of transcription from Pol II promoter|regulation of ROS metabolic process by activation of global transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolic process by up-regulation of global transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolism by activation of global transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolism by positive regulation of global transcription from Pol II promoter|regulation of reactive oxygen species metabolism by positive regulation of transcription from Pol II promoter|regulation of reactive oxygen species metabolism by upregulation of transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolic process by stimulation of transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolism by up-regulation of transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolic process by activation of transcription from RNA polymerase II promoter|regulation of ROS metabolic process by upregulation of global transcription from RNA polymerase II promoter|regulation of ROS metabolic process by stimulation of transcription from RNA polymerase II promoter|regulation of ROS metabolic process by up regulation of transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolism by activation of transcription from RNA polymerase II promoter|regulation of ROS metabolic process by upregulation of transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolism by positive regulation of transcription from RNA polymerase II promoter, global|regulation of ROS metabolic process by positive regulation of transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolic process by positive regulation of gene-specific transcription from RNA polymerase II promoter|regulation of ROS metabolic process by positive regulation of transcription from RNA polymerase II promoter, global|regulation of ROS metabolic process by up-regulation of global transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolism by positive regulation of gene-specific transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolism by positive regulation of transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolism by stimulation of transcription from RNA polymerase II promoter|regulation of ROS metabolic process by up regulation of global transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolic process by positive regulation of global transcription from Pol II promoter|regulation of reactive oxygen species metabolic process by up-regulation of transcription from RNA polymerase II promoter|regulation of ROS metabolic process by up-regulation of transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolic process by up regulation of transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolism by upregulation of global transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolism by stimulation of global transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolic process by upregulation of transcription from RNA polymerase II promoter|regulation of ROS metabolic process by activation of transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolism by up-regulation of global transcription from RNA polymerase II promoter|regulation of ROS metabolic process by positive regulation of global transcription from Pol II promoter|regulation of reactive oxygen species metabolic process by stimulation of global transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolic process by positive regulation of transcription from Pol II promoter|regulation of reactive oxygen species metabolic process by positive regulation of transcription from RNA polymerase II promoter, global|regulation of ROS metabolic process by positive regulation of gene-specific transcription from RNA polymerase II promoter|regulation of ROS metabolic process by stimulation of global transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolism by up regulation of transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolism by up regulation of global transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolic process by up regulation of global transcription from RNA polymerase II promoter							kmv	2015-07-17T18:11:59Z					biological_process											owl:Class	
GO:0021929	biolink:NamedThing	stellate cell precursor proliferation	The multiplication or reproduction of neuroblasts that will give rise to stellate cells. A cerebellar stellate cell is an inhibitory GABAergic interneuron found in the cerebellar cortex.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0021923	biolink:NamedThing	cell proliferation in hindbrain ventricular zone	The multiplication or reproduction of cells, resulting in the expansion of a cell population in the hindbrain region that is adjacent to the ventricular cavity.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0071041	biolink:NamedThing	antisense RNA transcript catabolic process	The chemical reactions and pathways resulting in the breakdown of antisense transcripts, i.e. transcripts that were produced from the antisense strand of a gene that produces a gene product and which often have a regulatory effect on the transcription of that gene product.	tmpzr1t_l9r_go_relaxed.owl								krc	2009-07-29T01:39:36Z					biological_process											owl:Class	
GO:0042868	biolink:NamedThing	antisense RNA metabolic process	The chemical reactions and pathways involving antisense RNA, an RNA molecule complementary in sequence to another RNA or DNA molecule, which, by binding the latter, acts to inhibit its function and/or completion of synthesis.	tmpzr1t_l9r_go_relaxed.owl	antisense RNA metabolism													biological_process											owl:Class	
GO:0010593	biolink:NamedThing	negative regulation of lamellipodium assembly	Any process that decreases the rate, frequency or extent of the formation of a lamellipodium, a thin sheetlike extension of the surface of a migrating cell.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of lamellipodium biogenesis													biological_process											owl:Class	
GO:1902744	biolink:NamedThing	negative regulation of lamellipodium organization	Any process that stops, prevents or reduces the frequency, rate or extent of lamellipodium organization.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of lamellipodium organization|downregulation of lamellipodium organization|inhibition of lamellipodium organization|down regulation of lamellipodium organization							als	2014-02-28T16:27:39Z					biological_process											owl:Class	
GO:0051819	biolink:NamedThing	induction by symbiont of tumor or growth in host	The process in which a symbiont causes the formation of a mass of cells in a host organism. While these growths are often called nodules, they are not formed as nitrogen-fixing structures, but rather to provide an environment for the symbiont to grow. In this sense they are parasitic structures rather than mutualistic.	tmpzr1t_l9r_go_relaxed.owl	induction by symbiont in host of tumor, nodule, or growth containing transformed cells|induction of tumor, nodule, or growth containing transformed cells in other organism during symbiotic interaction|induction of tumor, nodule, or growth in other organism during symbiotic interaction|induction by symbiont in host of tumor, nodule, or growth|induction by symbiont of nodulation, tumor or growth in host|induction of tumor, nodule, or growth containing transformed cells in other organism involved in symbiotic interaction|induction of tumor, nodule, or growth in other organism involved in symbiotic interaction											GO:0051820|GO:0044005|GO:0044006		biological_process											owl:Class	
GO:0018031	biolink:NamedThing	peptidyl-lysine N6-palmitoyltransferase activity	Catalysis of the transfer of a palmitoyl group to the N6 nitrogen atom on a lysine residue of a peptide or protein molecule.	tmpzr1t_l9r_go_relaxed.owl					EC:2.3.1.-									molecular_function											owl:Class	
GO:0043576	biolink:NamedThing	regulation of respiratory gaseous exchange	Any process that modulates the frequency, rate or extent of the process of gaseous exchange between an organism and its environment.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0020028	biolink:NamedThing	endocytic hemoglobin import into cell	The directed movement of hemoglobin into a cell by receptor-mediated endocytosis.	tmpzr1t_l9r_go_relaxed.owl	endocytic hemoglobin import|haemoglobin uptake|hemoglobin uptake													biological_process											owl:Class	
GO:0140394	biolink:NamedThing	ABC-type azole transporter activity	Enables the transfer of azoles, heterocyclic compound found in many biologically important substances, from one side of a membrane to the other according to the reaction: ATP + H2O + azole(in) = ADP + phosphate + azole(out).	tmpzr1t_l9r_go_relaxed.owl	azole ABC transporter activity|ATPase-coupled azole transmembrane transporter activity				RHEA:33503			pg	2019-11-28T18:29:48Z					molecular_function											owl:Class	
GO:0099092	biolink:NamedThing	postsynaptic density, intracellular component	A network of proteins adjacent to the postsynaptic membrane forming an electron dense disc. Its major components include neurotransmitter receptors and the proteins that spatially and functionally organize neurotransmitter receptors in the adjacent membrane, such as anchoring and scaffolding molecules, signaling enzymes and cytoskeletal components.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:1901710	biolink:NamedThing	regulation of homoserine biosynthetic process	Any process that modulates the frequency, rate or extent of homoserine biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of homoserine formation|regulation of homoserine biosynthesis|regulation of homoserine anabolism|regulation of homoserine synthesis							mcc	2012-12-19T16:01:56Z					biological_process											owl:Class	
GO:0098838	biolink:NamedThing	folate transmembrane transport	The process in which a folic acid, or one of its derivatives (dihydrofolate, tetrahydrofolate, methylene-tetrahydrofolate or methyl-tetrahydrofolate) is transported across a membrane.	tmpzr1t_l9r_go_relaxed.owl	reduced folate transmembrane transport|folic acid transmembrane transport	https://github.com/geneontology/go-ontology/issues/15461												biological_process											owl:Class	
GO:0016603	biolink:NamedThing	glutaminyl-peptide cyclotransferase activity	Catalysis of the reaction: L-glutaminyl-peptide = 5-oxoprolyl-peptide + NH3.	tmpzr1t_l9r_go_relaxed.owl	glutaminyl-transfer ribonucleate cyclotransferase activity|L-glutaminyl-peptide gamma-glutamyltransferase (cyclizing)|glutaminyl-tRNA cyclotransferase activity|glutaminyl cyclase activity				MetaCyc:GLUTAMINYL-PEPTIDE-CYCLOTRANSFERASE-RXN|EC:2.3.2.5|RHEA:23652									molecular_function											owl:Class	
GO:0031551	biolink:NamedThing	regulation of brain-derived neurotrophic factor-activated receptor activity	Any process that modulates the frequency, rate or extent of brain-derived neurotrophic factor-activated receptor activity.	tmpzr1t_l9r_go_relaxed.owl	regulation of BDNF receptor activity|regulation of brain-derived neurotrophic factor receptor activity													biological_process											owl:Class	
GO:0071160	biolink:NamedThing	cyanophycin synthetase activity (L-aspartate-adding)	Catalysis of the reaction: ATP + [L-Asp(4-L-Arg)]n + L-Asp = ADP + phosphate + [L-Asp(4-L-Arg)]n-L-Asp.	tmpzr1t_l9r_go_relaxed.owl					EC:6.3.2.29|RHEA:13277			mah	2009-11-17T05:18:17Z					molecular_function											owl:Class	
GO:0043860	biolink:NamedThing	cyanophycin synthetase activity	Catalysis of the ATP-dependent polymerization of arginine and aspartate to multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer).	tmpzr1t_l9r_go_relaxed.owl	cphA				EC:6.3.1.-									molecular_function											owl:Class	
GO:0046062	biolink:NamedThing	dCDP metabolic process	The chemical reactions and pathways involving dCDP, deoxycytidine 5'-diphosphate.	tmpzr1t_l9r_go_relaxed.owl	dCDP metabolism													biological_process											owl:Class	
GO:0015310	biolink:NamedThing	benomyl:proton antiporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + benomyl(in) = H+(in) + benomyl(out).	tmpzr1t_l9r_go_relaxed.owl	benomyl:hydrogen antiporter activity													molecular_function											owl:Class	
GO:0036344	biolink:NamedThing	platelet morphogenesis	Generation and organization of a platelet, a non-nucleated disk-shaped cell formed by extrusion from megakaryocytes, found in the blood of all mammals, and mainly involved in blood coagulation.	tmpzr1t_l9r_go_relaxed.owl								bf	2012-09-11T15:15:35Z					biological_process											owl:Class	
GO:0039638	biolink:NamedThing	lipopolysaccharide-mediated virion attachment to host cell	The process by which a virion attaches to a host cell by binding to a lipopolysaccharide (LPS) on the host cell surface.	tmpzr1t_l9r_go_relaxed.owl	LPS binding involved in viral attachment to host cell|lipopolysaccharide binding involved in viral attachment to host cell|virion attachment, binding to host lipopolysaccharide							bf	2012-08-17T10:13:06Z					biological_process											owl:Class	
GO:0015146	biolink:NamedThing	pentose transmembrane transporter activity	Enables the transfer of a pentose sugar from one side of a membrane to the other. Pentose is a monosaccharide with 5 carbon atoms.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1903487	biolink:NamedThing	regulation of lactation	Any process that modulates the frequency, rate or extent of lactation.	tmpzr1t_l9r_go_relaxed.owl								mr	2014-09-24T14:44:13Z					biological_process											owl:Class	
GO:0034748	biolink:NamedThing	Par3-APC-KIF3A complex	A protein complex that contains Par3, the tumor suppressor protein adenomatous polyposis coli (APC), and the kinesin-related protein KIF3A; involved in establishing neuronal cell polarity.	tmpzr1t_l9r_go_relaxed.owl						Note that the gene/protein name 'APC' should not be confused with the abbreviation for 'anaphase promoting complex'.								cellular_component											owl:Class	
GO:0036493	biolink:NamedThing	positive regulation of translation in response to endoplasmic reticulum stress	Any process that activates, or increases the frequency, rate or extent of translation as a result of endoplasmic reticulum stress.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of translation in response to ER stress							bf	2015-02-05T10:09:51Z					biological_process											owl:Class	
GO:0061540	biolink:NamedThing	octopamine secretion, neurotransmission	The controlled release of octopamine by a cell, in which the octopamine acts as a neurotransmitter.	tmpzr1t_l9r_go_relaxed.owl								dph	2013-06-21T16:24:47Z					biological_process											owl:Class	
GO:0061539	biolink:NamedThing	octopamine secretion	The controlled release of octopamine by a cell.	tmpzr1t_l9r_go_relaxed.owl								dph	2013-06-21T16:24:02Z					biological_process											owl:Class	
GO:0048661	biolink:NamedThing	positive regulation of smooth muscle cell proliferation	Any process that activates or increases the rate or extent of smooth muscle cell proliferation.	tmpzr1t_l9r_go_relaxed.owl	activation of smooth muscle cell proliferation|stimulation of smooth muscle cell proliferation|positive regulation of SMC proliferation|up-regulation of smooth muscle cell proliferation|up regulation of smooth muscle cell proliferation|upregulation of smooth muscle cell proliferation													biological_process											owl:Class	
GO:0046522	biolink:NamedThing	S-methyl-5-thioribose kinase activity	Catalysis of the reaction: S-methyl-5-thio-D-ribose + ATP = S-methyl-5-thio-alpha-D-ribose 1-phosphate + ADP + 2 H(+).	tmpzr1t_l9r_go_relaxed.owl	5-methylthioribose kinase (phosphorylating)|ATP:S5-methyl-5-thio-D-ribose 1-phosphotransferase activity|ATP:S-methyl-5-thio-D-ribose 1-phosphotransferase activity|5-methylthioribose kinase activity|MTR kinase activity|methylthioribose kinase activity				EC:2.7.1.100|KEGG_REACTION:R04143|MetaCyc:5-METHYLTHIORIBOSE-KINASE-RXN|RHEA:22312									molecular_function											owl:Class	
GO:0035192	biolink:NamedThing	nuclear cortical migration	The symmetric outward movement of the syncytial nuclei from their positions in the ellipsoid toward the periphery of the embryo, during mitotic cycles 8 and 9. This movement results in the placement of nuclei in a uniform monolayer at the cortex of the developing embryo.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0061613	biolink:NamedThing	glycolytic process from glycerol	The glycolytic process in which glycerol is catabolized to pyruvate generating ATP and NADH.	tmpzr1t_l9r_go_relaxed.owl								dph	2014-04-04T08:26:57Z					biological_process											owl:Class	
GO:0046713	biolink:NamedThing	borate transport	The directed movement of borate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Borate is the anion (BO3)3-; boron is a group 13 element, with properties which are borderline between metals and non-metals.	tmpzr1t_l9r_go_relaxed.owl	boron transport													biological_process											owl:Class	
GO:0061903	biolink:NamedThing	positive regulation of 1-phosphatidylinositol-3-kinase activity	Any process that starts or increases the frequency or rate of 1-phosphatidylinositol-3-kinase activity.	tmpzr1t_l9r_go_relaxed.owl								dph	2017-06-22T19:54:53Z					biological_process											owl:Class	
GO:0061901	biolink:NamedThing	regulation of 1-phosphatidylinositol-3-kinase activity	Any process that modulates the frequency, rate or extent of 1-phosphatidylinositol-3-kinase activity.	tmpzr1t_l9r_go_relaxed.owl								dph	2017-06-22T19:34:56Z					biological_process											owl:Class	
GO:0006112	biolink:NamedThing	energy reserve metabolic process	The chemical reactions and pathways by which a cell derives energy from stored compounds such as fats or glycogen.	tmpzr1t_l9r_go_relaxed.owl	energy reserve metabolism													biological_process											owl:Class	
GO:0015980	biolink:NamedThing	energy derivation by oxidation of organic compounds	The chemical reactions and pathways by which a cell derives energy from organic compounds; results in the oxidation of the compounds from which energy is released.	tmpzr1t_l9r_go_relaxed.owl	chemoorganotrophy													biological_process											owl:Class	
GO:0030869	biolink:NamedThing	RENT complex	A protein complex that mediates transcriptional silencing at the rDNA locus (the name derives from regulator of nucleolar silencing and telophase). In Saccharomyces the complex contains Net1p, Sir2p, Cdc14p, and at least one more subunit.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0005677	biolink:NamedThing	chromatin silencing complex	Any protein complex that mediates changes in chromatin structure that result in transcriptional silencing.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0005217	biolink:NamedThing	intracellular ligand-gated ion channel activity	Enables the transmembrane transfer of an ion by a channel that opens when a specific intracellular ligand has been bound by the channel complex or one of its constituent parts.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0060570	biolink:NamedThing	negative regulation of peptide hormone processing	Any process that decreases the rate, frequency or extent of peptide hormone processing. Peptide hormone processing is the generation of a mature peptide hormone by posttranslational processing of a prohormone.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-04-29T03:24:55Z					biological_process											owl:Class	
GO:0060568	biolink:NamedThing	regulation of peptide hormone processing	Any process that modulates the rate, frequency or extent of peptide hormone processing. Peptide hormone processing is the generation of a mature peptide hormone by posttranslational processing of a prohormone.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-04-29T03:16:05Z					biological_process											owl:Class	
GO:0006038	biolink:NamedThing	cell wall chitin biosynthetic process	The chemical reactions and pathways resulting in the formation of cell wall chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues, found in the walls of cells.	tmpzr1t_l9r_go_relaxed.owl	cell wall chitin synthesis|cell wall chitin formation|cell wall chitin anabolism|cell wall chitin biosynthesis													biological_process											owl:Class	
GO:0061773	biolink:NamedThing	eNoSc complex	A chromatin silencing complex that recruits histone-modifying enzymes and upregulates silencing of rDNA in response to glucose starvation.	tmpzr1t_l9r_go_relaxed.owl	energy dependent nucleolar silencing complex							dph	2016-07-09T10:12:30Z					cellular_component											owl:Class	
GO:0007622	biolink:NamedThing	rhythmic behavior	The specific behavior of an organism that recur with measured regularity.	tmpzr1t_l9r_go_relaxed.owl	rhythmic behavioral response to stimulus|rhythmic behaviour|rhythmic behavioural response to stimulus													biological_process											owl:Class	
GO:1905490	biolink:NamedThing	negative regulation of sensory neuron axon guidance	Any process that stops, prevents or reduces the frequency, rate or extent of sensory neuron axon guidance.	tmpzr1t_l9r_go_relaxed.owl	inhibition of sensory neuron axon guidance|downregulation of sensory neuron axon guidance|down regulation of sensory neuron axon guidance|down-regulation of sensory neuron axon guidance							hbye	2016-09-23T13:19:04Z					biological_process											owl:Class	
GO:0060628	biolink:NamedThing	regulation of ER to Golgi vesicle-mediated transport	Any process that modulates the rate, frequency, or extent of ER to Golgi vesicle-mediated transport, the directed movement of substances from the endoplasmic reticulum (ER) to the Golgi, mediated by COP II vesicles. Small COP II coated vesicles form from the ER and then fuse directly with the cis-Golgi. Larger structures are transported along microtubules to the cis-Golgi.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-05-18T02:37:00Z					biological_process											owl:Class	
GO:0018506	biolink:NamedThing	maleylacetate reductase activity	Catalysis of the reaction: 3-oxoadipate + NAD(P)+ = 2-maleylacetate + NAD(P)H + H+.	tmpzr1t_l9r_go_relaxed.owl	3-oxoadipate:NAD(P)+ oxidoreductase activity|maleolylacetate reductase activity				EC:1.3.1.32|UM-BBD_enzymeID:e0063|MetaCyc:MALEYLACETATE-REDUCTASE-RXN									molecular_function											owl:Class	
GO:0005295	biolink:NamedThing	neutral amino acid:sodium symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: neutral amino acid(out) + Na+(out) = neutral amino acid(in) + Na+(in).	tmpzr1t_l9r_go_relaxed.owl	neutral amino acid-sodium cotransporter|sodium/neutral amino acid transporter											GO:0005282		molecular_function											owl:Class	
GO:0005283	biolink:NamedThing	amino acid:sodium symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: amino acid(out) + Na+(out) = amino acid(in) + Na+(in).	tmpzr1t_l9r_go_relaxed.owl	sodium:amino acid symporter activity|sodium/amino acid transporter activity|glutamate/aspartate:sodium symporter activity|insulin-activated sodium:amino acid symporter activity|insulin-activated sodium:amino acid transporter activity|isoleucine/valine:sodium symporter activity|sodium/excitatory amino acid cotransporter activity|threonine/serine:sodium symporter activity|sodium/excitatory amino acid symporter activity|sodium:amino acid transporter activity|insulin-activated sodium/amino acid transporter activity											GO:0005285|GO:0005284		molecular_function											owl:Class	
GO:0036475	biolink:NamedThing	neuron death in response to oxidative stress	Any biological process that results in permanent cessation of all vital functions of a neuron upon exposure to an oxidative stress stimulus.	tmpzr1t_l9r_go_relaxed.owl	oxidative stress-induced neuron death|neuronal cell death in response to oxidative stress					This term should not be used for direct annotation. The only exception should be when experimental data (e.g., staining with trypan blue or propidium iodide or use of neuron-specific markers) show that neuron death has occurred, but fail to provide details on death modality (accidental versus programmed). When information is provided on the neuron death mechanism, annotations should be made to the appropriate descendant of 'cell death' (such as, but not limited to, GO:0097300 'programmed necrotic cell death', GO:0006915 'apoptotic process' or GO:0010421 'hydrogen peroxide-mediated programmed cell death'), and the cell type captured as an annotation extension; or the term GO:0051402 'neuron apoptotic process' may be considered, if appropriate.		bf	2014-07-21T11:44:40Z					biological_process											owl:Class	
GO:0070997	biolink:NamedThing	neuron death	The process of cell death in a neuron.	tmpzr1t_l9r_go_relaxed.owl	neuronal cell death|neuron cell death					This term should not be used for direct annotation. The only exception should be when experimental data (e.g., staining with trypan blue or propidium iodide or use of neuron-specific markers) show that neuron death has occurred, but fail to provide details on death modality (accidental versus programmed). When information is provided on the neuron death mechanism, annotations should be made to the appropriate descendant of 'cell death' (such as, but not limited to, GO:0097300 'programmed necrotic cell death' or GO:0006915 'apoptotic process'), and the cell type captured as an annotation extension; or the term GO:0051402 'neuron apoptotic process' may be considered, if appropriate.		mah	2009-11-03T02:37:17Z					biological_process											owl:Class	
GO:0072438	biolink:NamedThing	response to DNA replication checkpoint signaling	A process that occurs in response to signals generated as a result of DNA replication checkpoint signaling.	tmpzr1t_l9r_go_relaxed.owl	DNA replication checkpoint effector process|response to signal involved in DNA replication checkpoint							mah	2010-12-08T04:53:12Z					biological_process											owl:Class	
GO:0047421	biolink:NamedThing	N-acyl-D-glutamate deacylase activity	Catalysis of the reaction: N-acyl-D-glutamate + H(2)O = D-glutamate + a carboxylate.	tmpzr1t_l9r_go_relaxed.owl	N-acyl-D-glutamate amidohydrolase activity				MetaCyc:3.5.1.82-RXN|RHEA:12833|EC:3.5.1.82|KEGG_REACTION:R01581									molecular_function											owl:Class	
GO:1901270	biolink:NamedThing	lipooligosaccharide catabolic process	The chemical reactions and pathways resulting in the breakdown of lipooligosaccharide.	tmpzr1t_l9r_go_relaxed.owl	lipooligosaccharide breakdown|lipooligosaccharide degradation|lipooligosaccharide catabolism							yaf	2012-08-17T14:31:48Z					biological_process											owl:Class	
GO:0018037	biolink:NamedThing	C-terminal peptidyl-aspartic acid amidation	The formation of a C-terminal peptidyl-aspartic acid 1-amide by hydrolysis and oxidation of an interior Asp-Gly peptide in a secreted protein.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0084									biological_process											owl:Class	
GO:0043465	biolink:NamedThing	regulation of fermentation	Any process that modulates the frequency, rate or extent of fermentation, the anaerobic enzymatic conversion of organic compounds, especially carbohydrates, to other compounds, especially to ethyl alcohol, resulting in energy in the form of adenosine triphosphate (ATP).	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0106071	biolink:NamedThing	positive regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway	Any process that activates or increases the frequency, rate or extent of an adenylate cyclase-activating G protein-coupled receptor signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of adenylate cyclase-activating G-protein coupled receptor signaling pathway							hjd	2017-11-28T18:38:52Z					biological_process											owl:Class	
GO:1900432	biolink:NamedThing	negative regulation of filamentous growth of a population of unicellular organisms in response to heat	Any process that stops, prevents or reduces the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to heat.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of filamentous growth of a population of unicellular organisms in response to heat|down regulation of filamentous growth of a population of unicellular organisms in response to heat|downregulation of filamentous growth of a population of unicellular organisms in response to heat|inhibition of filamentous growth of a population of unicellular organisms in response to heat							di	2012-04-25T05:54:15Z					biological_process											owl:Class	
GO:0046053	biolink:NamedThing	dAMP metabolic process	The chemical reactions and pathways involving dAMP, deoxyadenosine monophosphate (2'-deoxyadenosine 5'-phosphate).	tmpzr1t_l9r_go_relaxed.owl	dAMP metabolism													biological_process											owl:Class	
GO:0015394	biolink:NamedThing	uridine:proton symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: uridine(out) + H+(out) = uridine(in) + H+(in).	tmpzr1t_l9r_go_relaxed.owl	uridine:hydrogen ion symporter activity|nucleoside (uridine) permease activity													molecular_function											owl:Class	
GO:0044751	biolink:NamedThing	cellular response to human chorionic gonadotropin stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a human chorionic gonadotropin stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to human chorionic gonadotrophin stimulus							jl	2012-11-20T16:19:45Z					biological_process											owl:Class	
GO:0071371	biolink:NamedThing	cellular response to gonadotropin stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gonadotropin stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to gonadotrophin stimulus							mah	2009-12-11T03:14:35Z					biological_process											owl:Class	
GO:0052612	biolink:NamedThing	adonirubin 3-hydroxylase activity	Catalysis of the reaction: adonirubin + a reduced electron acceptor + oxygen = 3S,3'S-astaxanthin + an oxidized electron acceptor + H2O.	tmpzr1t_l9r_go_relaxed.owl	carotene beta-ring hydroxylase activity|beta-ring carotenoid 3-hydroxylase activity|beta-carotene hydroxylase activity				MetaCyc:RXN-8187									molecular_function											owl:Class	
GO:0009603	biolink:NamedThing	detection of symbiotic fungus	The series of events in which a stimulus from a symbiotic fungus, a fungus living in close physical association with another organism, is received and converted into a molecular signal.	tmpzr1t_l9r_go_relaxed.owl	perception of symbiotic fungi|perception of symbiotic fungus|detection of symbiotic fungi													biological_process											owl:Class	
GO:0016046	biolink:NamedThing	detection of fungus	The series of events in which a stimulus from a fungus is received and converted into a molecular signal.	tmpzr1t_l9r_go_relaxed.owl	detection of fungi|detection of parasitic fungus|perception of parasitic fungi|perception of parasitic fungus|perception of fungus|detection of parasitic fungi|perception of fungi											GO:0016047|GO:0009599		biological_process											owl:Class	
GO:0060741	biolink:NamedThing	prostate gland stromal morphogenesis	The process in which the prostate gland stroma is generated and organized. The prostate gland stroma is made up of the mesenchymal or fibroblast cells of the prostate gland.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-06-16T09:27:01Z					biological_process											owl:Class	
GO:0061027	biolink:NamedThing	umbilical cord development	The process whose specific outcome is the development of the umbilical cord, from its formation to the mature structure. The umbilical cord is an organ or embryonic origin consisting of the 2 umbilical arteries and the one umbilical vein. The umbilical cord connects the cardiovascular system of the fetus to the mother via the placenta.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-02-09T09:09:22Z					biological_process											owl:Class	
GO:0075132	biolink:NamedThing	suppression by symbiont of host protein kinase-mediated signal transduction	Any process in which the symbiont organism stops, prevents, or reduces the frequency, rate or extent of protein kinase-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	negative regulation by symbiont of host protein kinase-mediated signal transduction					Note that this term is used to annotate gene products of the symbiont. To annotate host gene products, consider the biological process term "negative regulation by host of symbiont protein kinase-mediated signal transduction ; GO:0075101".								biological_process											owl:Class	
GO:0075130	biolink:NamedThing	modulation by symbiont of host protein kinase-mediated signal transduction	Any process in which the symbiont modulates the frequency, rate or extent of protein kinase-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl						Note that this term is used to annotate gene products of the symbiont. To annotate host gene products, consider the biological process term "modulation by host of symbiont protein kinase-mediated signal transduction ; GO:0075099".								biological_process											owl:Class	
GO:0070595	biolink:NamedThing	(1->3)-alpha-glucan metabolic process	The chemical reactions and pathways involving (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds.	tmpzr1t_l9r_go_relaxed.owl	1,3-alpha-glucan metabolic process|alpha-1,3 glucan metabolism|alpha-1,3 glucan metabolic process|1,3-alpha-glucan metabolism							mah	2009-04-28T03:35:03Z					biological_process											owl:Class	
GO:1905368	biolink:NamedThing	peptidase complex	A protein complex which is capable of peptidase activity.	tmpzr1t_l9r_go_relaxed.owl	tryptase complex|protease complex					An example of this is PLAU in human (UniProt symbol P00749) in PMID:1689240 (inferred from direct assay).		bhm	2016-08-16T12:49:36Z					cellular_component											owl:Class	
GO:0002553	biolink:NamedThing	histamine secretion by mast cell	The regulated release of histamine by a mast cell or group of mast cells.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1904295	biolink:NamedThing	regulation of osmolarity-sensing cation channel activity	Any process that modulates the frequency, rate or extent of osmolarity-sensing cation channel activity.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-06-09T17:35:40Z					biological_process											owl:Class	
GO:0071210	biolink:NamedThing	protein insertion into membrane raft	The process in which a protein is incorporated into a membrane raft. Membrane rafts are small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes.	tmpzr1t_l9r_go_relaxed.owl	establishment of protein localization to membrane raft							mah	2009-11-25T02:11:46Z					biological_process											owl:Class	
GO:1903044	biolink:NamedThing	protein localization to membrane raft	A process in which a protein is transported to, or maintained in, a location within a membrane raft.	tmpzr1t_l9r_go_relaxed.owl	protein localisation to membrane raft|protein localization in membrane raft|protein localisation in membrane raft							dl	2014-05-21T10:49:03Z					biological_process											owl:Class	
GO:1900797	biolink:NamedThing	cordyol C metabolic process	The chemical reactions and pathways involving cordyol C.	tmpzr1t_l9r_go_relaxed.owl	cordyol C metabolism							di	2012-06-04T09:47:48Z					biological_process											owl:Class	
GO:0047796	biolink:NamedThing	cyclohexane-1,3-dione hydrolase activity	Catalysis of the reaction: cyclohexane-1,3-dione + H(2)O = 5-oxohexanoate + H(+).	tmpzr1t_l9r_go_relaxed.owl	cyclohexane-1,3-dione acylhydrolase (decyclizing)|1,3-cyclohexanedione hydrolase activity				RHEA:16473|EC:3.7.1.10|KEGG_REACTION:R03211|MetaCyc:CYCLOHEXANE-13-DIONE-HYDROLASE-RXN									molecular_function											owl:Class	
GO:0047589	biolink:NamedThing	5-aminovalerate transaminase activity	Catalysis of the reaction: 2-oxoglutarate + 5-aminopentanoate = 5-oxopentanoate + L-glutamate.	tmpzr1t_l9r_go_relaxed.owl	5-aminopentanoate:2-oxoglutarate aminotransferase activity|delta-aminovalerate aminotransferase activity|5-aminovalerate aminotransferase activity|delta-aminovalerate transaminase activity				MetaCyc:VAGL-RXN|KEGG_REACTION:R02274|EC:2.6.1.48|RHEA:10212									molecular_function											owl:Class	
GO:0019502	biolink:NamedThing	stachydrine metabolic process	The chemical reactions and pathways involving stachydrine, N-methylproline methylbetaine, the betaine derivative of L-proline found in alfalfa, chrysanthemum, and citrus plants.	tmpzr1t_l9r_go_relaxed.owl	stachydrine metabolism													biological_process											owl:Class	
GO:0005683	biolink:NamedThing	U7 snRNP	A ribonucleoprotein complex that contains the U7 snRNA and is required for the 3'-end processing of replication-dependent histone pre-mRNAs.	tmpzr1t_l9r_go_relaxed.owl	snRNP U7													cellular_component											owl:Class	
GO:0030532	biolink:NamedThing	small nuclear ribonucleoprotein complex	A ribonucleoprotein complex that contains at least one RNA of the small nuclear RNA (snRNA) class and as well as its associated proteins. These are typically named after the snRNA(s) they contain, e.g. U1 snRNP, U4/U6 snRNP, or 7SK snRNP. Many, of these complexes become part of the spliceosome involved in splicing of nuclear mRNAs. Others are involved in regulation of transcription elongation or 3'-end processing of replication-dependent histone pre-mRNAs.	tmpzr1t_l9r_go_relaxed.owl	small nuclear ribonucleoprotein|snRNP				Wikipedia:SnRNP									cellular_component											owl:Class	
GO:0045006	biolink:NamedThing	DNA deamination	The removal of an amino group from a nucleotide base in DNA. An example is the deamination of cytosine to produce uracil.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0018534	biolink:NamedThing	nitrilotriacetate dehydrogenase activity	Catalysis of the reaction: nitrilotriacetate + OH- = H+ + 2 e- + glyoxylate + iminodiacetate.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0588|EC:1.5.99.-									molecular_function											owl:Class	
GO:0140581	biolink:NamedThing	P-type monovalent copper transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Cu+(in) -> ADP + phosphate + Cu+(out).	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/20699			EC:7.2.2.8|RHEA:25792	Note that this enzyme transports Cu(+) or Ag(+), and cannot transport the divalent ions, contrary to EC:7.2.2.9, which mainly transports the divalent copper ion (source: EC:7.2.2.8).		pg	2021-01-18T11:15:13Z					molecular_function											owl:Class	
GO:1902632	biolink:NamedThing	positive regulation of membrane hyperpolarization	Any process that activates or increases the frequency, rate or extent of membrane hyperpolarization.	tmpzr1t_l9r_go_relaxed.owl	upregulation of membrane hyperpolarization|up-regulation of membrane hyperpolarization|activation of membrane hyperpolarization|up regulation of membrane hyperpolarization							krc	2014-01-17T18:28:14Z					biological_process											owl:Class	
GO:0015425	biolink:NamedThing	ATPase-coupled nonpolar-amino acid transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + nonpolar amino acid(out) = ADP + phosphate + nonpolar amino acid(in).	tmpzr1t_l9r_go_relaxed.owl	nonpolar-amino acid-transporting ATPase activity|leucine/isoleucine/valine porter activity|nonpolar-amino acid ABC transporter|nonpolar amino acid-transporting ATPase activity|ATP-dependent nonpolar-amino acid transporter activity|nonpolar-amino-acid-transporting ATPase activity				MetaCyc:3.6.3.22-RXN|EC:7.4.2.2|TC:3.A.1.4.1									molecular_function											owl:Class	
GO:0015424	biolink:NamedThing	ABC-type amino acid transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + amino acid(out/in) = ADP + phosphate + amino acid(in/out).	tmpzr1t_l9r_go_relaxed.owl	amino acid-exporting ATPase activity|amino acid-importing ATPase activity|amino acid-transporting ATPase activity|amino acid ABC transporter|ATPase-coupled amino acid transmembrane transporter activity|ATP-dependent amino acid transmembrane transporter activity											GO:0032520|GO:0032518		molecular_function											owl:Class	
GO:0042941	biolink:NamedThing	D-alanine transport	The directed movement of D-alanine, the D-enantiomer of 2-aminopropanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0032328	biolink:NamedThing	alanine transport	The directed movement of alanine, 2-aminopropanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1990405	biolink:NamedThing	protein antigen binding	Binding to a protein antigen.	tmpzr1t_l9r_go_relaxed.owl								pm	2014-06-30T13:19:55Z					molecular_function											owl:Class	
GO:0003823	biolink:NamedThing	antigen binding	Binding to an antigen, any substance which is capable of inducing a specific immune response and of reacting with the products of that response, the specific antibody or specifically sensitized T-lymphocytes, or both. Binding may counteract the biological activity of the antigen.	tmpzr1t_l9r_go_relaxed.owl	antibody|opsonin activity|B cell receptor activity|immunoglobulin													molecular_function											owl:Class	
GO:1904444	biolink:NamedThing	regulation of establishment of Sertoli cell barrier	Any process that modulates the frequency, rate or extent of establishment of Sertoli cell barrier.	tmpzr1t_l9r_go_relaxed.owl	regulation of establishment of blood-testis barrier|regulation of establishment of BTB|regulation of establishment of SCB							sl	2015-07-06T16:00:41Z					biological_process											owl:Class	
GO:1990344	biolink:NamedThing	secondary cell septum biogenesis	A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a secondary cell septum following nuclear division.	tmpzr1t_l9r_go_relaxed.owl								mah	2014-03-24T13:24:48Z					biological_process											owl:Class	
GO:1903501	biolink:NamedThing	positive regulation of mitotic actomyosin contractile ring assembly	Any process that activates or increases the frequency, rate or extent of mitotic actomyosin contractile ring assembly.	tmpzr1t_l9r_go_relaxed.owl	activation of mitotic actomyosin contractile ring assembly|positive regulation of cytokinesis, actomyosin contractile ring assembly involved in mitotic cytokinesis|upregulation of cytokinesis, actomyosin contractile ring assembly involved in mitotic cytokinesis|up-regulation of cytokinesis, actomyosin contractile ring assembly involved in mitotic cytokinesis|up-regulation of contractile ring assembly involved in mitotic cytokinesis|up regulation of mitotic actomyosin contractile ring assembly|activation of actomyosin contractile ring assembly involved in cytokinesis after mitosis|upregulation of contractile ring assembly involved in mitotic cytokinesis|up regulation of cytokinesis, actomyosin contractile ring assembly involved in mitotic cytokinesis|upregulation of mitotic actomyosin contractile ring assembly|up-regulation of actomyosin contractile ring assembly involved in cytokinesis after mitosis|activation of cytokinesis, actomyosin contractile ring assembly involved in mitotic cytokinesis|positive regulation of contractile ring assembly involved in mitotic cytokinesis|activation of contractile ring assembly involved in mitotic cytokinesis|up-regulation of mitotic actomyosin contractile ring assembly|upregulation of actomyosin contractile ring assembly involved in cytokinesis after mitosis|up regulation of contractile ring assembly involved in mitotic cytokinesis|up regulation of actomyosin contractile ring assembly involved in cytokinesis after mitosis|positive regulation of actomyosin contractile ring assembly involved in cytokinesis after mitosis|positive regulation of mitotic cytokinesis, actomyosin contractile ring assembly							pr	2014-09-30T10:14:07Z					biological_process											owl:Class	
GO:0051718	biolink:NamedThing	DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates	Catalysis of the reaction: S-adenosyl-L-methionine + CpG (in DNA) = S-adenosyl-L-homocysteine + 5-MeCpG (in DNA).	tmpzr1t_l9r_go_relaxed.owl	M.BsuRIb|HpaII methylase|M.BsuRIa|HpaII' methylase				Reactome:R-HSA-5334151									molecular_function											owl:Class	
GO:0071854	biolink:NamedThing	cell wall macromolecule catabolic process involved in fungal-type cell wall disassembly	The chemical reactions and pathways that result in the breakdown of macromolecules that form part of a cell wall, and contributes to the breakdown of the fungal-type cell wall.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-09-10T03:12:08Z					biological_process											owl:Class	
GO:0070910	biolink:NamedThing	cell wall macromolecule catabolic process involved in cell wall disassembly	The chemical reactions and pathways that result in the breakdown of macromolecules that form part of a cell wall, and contributes to the breakdown of the cell wall.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-09-09T02:40:57Z					biological_process											owl:Class	
GO:0060547	biolink:NamedThing	negative regulation of necrotic cell death	Any process that decreases the rate, frequency or extent of necrotic cell death. Necrotic cell death is a cell death process that is morphologically characterized by a gain in cell volume (oncosis), swelling of organelles, plasma membrane rupture and subsequent loss of intracellular contents.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-04-13T01:51:25Z					biological_process											owl:Class	
GO:0090359	biolink:NamedThing	negative regulation of abscisic acid biosynthetic process	Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of abscisic acid.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of abscisic acid biosynthesis							tb	2010-06-29T02:47:12Z					biological_process											owl:Class	
GO:0034526	biolink:NamedThing	2-methylnaphthalene hydroxylase activity	Catalysis of the reaction: 2-methylnaphthalene + NADH + O2 + H+ = 2-hydroxymethylnaphthalene + NAD+ + H2O.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0788|EC:1.14.13.-									molecular_function											owl:Class	
GO:0021738	biolink:NamedThing	fastigial nucleus development	The process whose specific outcome is the progression of the fastigial nucleus over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0034132	biolink:NamedThing	negative regulation of toll-like receptor 1 signaling pathway	Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 1 signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of TLR1 signaling pathway|negative regulation of toll-like receptor 1 signalling pathway													biological_process											owl:Class	
GO:0015513	biolink:NamedThing	high-affinity secondary active nitrite transmembrane transporter activity	Catalysis of the transfer of nitrite from one side of the membrane to the other, up the solute's concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. In high affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.	tmpzr1t_l9r_go_relaxed.owl	nitrite uptake permease activity													molecular_function											owl:Class	
GO:0006172	biolink:NamedThing	ADP biosynthetic process	The chemical reactions and pathways resulting in the formation of ADP, adenosine 5'-diphosphate.	tmpzr1t_l9r_go_relaxed.owl	ADP formation|ADP synthesis|ADP biosynthesis|ADP anabolism													biological_process											owl:Class	
GO:0033285	biolink:NamedThing	ATPase-coupled monocarboxylic acid transmembrane transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + monocarboxylic acid(out/in) = ADP + phosphate + monocarboxylic acid(in/out).	tmpzr1t_l9r_go_relaxed.owl	monocarboxylic acid-transporting ATPase activity|ATP-dependent monocarboxylic acid transmembrane transporter activity													molecular_function											owl:Class	
GO:0061364	biolink:NamedThing	apoptotic process involved in luteolysis	The apoptotic process that contributes to luteolysis.	tmpzr1t_l9r_go_relaxed.owl	structural luteolysis|apoptosis involved in luteolysis							dph	2010-10-14T03:18:49Z					biological_process											owl:Class	
GO:0022031	biolink:NamedThing	telencephalon astrocyte cell migration	The orderly movement of an astrocyte cell through the telencephalon.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0043615	biolink:NamedThing	astrocyte cell migration	The orderly movement of an astrocyte, a class of large neuroglial (macroglial) cells in the central nervous system, the largest and most numerous neuroglial cells in the brain and spinal cord.	tmpzr1t_l9r_go_relaxed.owl	astrocytic glial cell migration|astrocyte migration													biological_process											owl:Class	
GO:0070286	biolink:NamedThing	axonemal dynein complex assembly	The aggregation, arrangement and bonding together of a set of components to form an axonemal dynein complex, a dynein complex found in eukaryotic cilia and flagella, in which the motor domain heads interact with adjacent microtubules to generate a sliding force which is converted to a bending motion.	tmpzr1t_l9r_go_relaxed.owl	dynein arm assembly													biological_process											owl:Class	
GO:0019854	biolink:NamedThing	L-ascorbic acid catabolic process	The chemical reactions and pathways resulting in the breakdown of L-ascorbic acid; L-ascorbic acid ionizes to give L-ascorbate, (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate, which is required as a cofactor in the oxidation of prolyl residues to hydroxyprolyl, and other reactions.	tmpzr1t_l9r_go_relaxed.owl	ascorbate catabolism|L-ascorbic acid catabolism|L-ascorbic acid breakdown|vitamin C catabolic process|vitamin C catabolism|ascorbate catabolic process|L-ascorbic acid degradation				MetaCyc:PWY0-301									biological_process											owl:Class	
GO:0140315	biolink:NamedThing	iron ion sequestering activity	The selective interaction of a protein with an iron ion to prevent it from interacting with other partners or inhibiting its localization to other areas of the cell.	tmpzr1t_l9r_go_relaxed.owl								pg	2019-03-28T10:10:33Z					molecular_function											owl:Class	
GO:1990097	biolink:NamedThing	SeqA-DNA complex	A protein-DNA complex that contains an oligomer of SeqA bound to GATC sites in methylated or newly-synthesized, hemi-methylated double-stranded DNA, with preference for the latter. Binding of SeqA to hemimethylated DNA sequesters oriC, prevents re-methylation of DNA by Dam and in turn stops premature re-initiation of replication during one replication cycle.	tmpzr1t_l9r_go_relaxed.owl	SeqA-dsDNA complex|SeqA-hemimethylation dsDNA complex|SeqA-hemimethylated DNA complex							bhm	2013-05-13T11:18:11Z					cellular_component											owl:Class	
GO:1904800	biolink:NamedThing	negative regulation of neuron remodeling	Any process that stops, prevents or reduces the frequency, rate or extent of neuron remodeling.	tmpzr1t_l9r_go_relaxed.owl	inhibition of axon pruning|down-regulation of axon pruning|down-regulation of neuron remodeling|downregulation of neuron remodeling|negative regulation of axon pruning|negative regulation of neuronal remodeling|down regulation of axon pruning|downregulation of axon pruning|inhibition of neuron remodeling|down regulation of neuronal remodeling|down regulation of neuron remodeling|inhibition of neuronal remodeling|downregulation of neuronal remodeling|down-regulation of neuronal remodeling					cyy-1 in C. Elegans (P34624) in PMID:21609829 (inferred from mutant phenotype)		es	2015-11-09T13:47:00Z					biological_process											owl:Class	
GO:1904799	biolink:NamedThing	regulation of neuron remodeling	Any process that modulates the frequency, rate or extent of neuron remodeling.	tmpzr1t_l9r_go_relaxed.owl	regulation of axon pruning|regulation of neuronal remodeling					cyy-1 in C. Elegans (P34624) in PMID:21609829 (inferred from mutant phenotype)		es	2015-11-09T13:46:52Z					biological_process											owl:Class	
GO:0033311	biolink:NamedThing	chlorophyll a biosynthetic process via phytyl diphosphate	The chemical reactions and pathways leading to the formation of chlorophyll a, via the intermediate phytyl diphosphate.	tmpzr1t_l9r_go_relaxed.owl	chlorophyll a biosynthetic process via phytyl-PP|chlorophyll a biosynthesis via phytyl diphosphate|chlorophyll a synthesis via phytyl diphosphate|chlorophyll a anabolism via phytyl diphosphate|chlorophyll a formation via phytyl chlorophyll a formation via phytyl-PP				MetaCyc:PWY-5086									biological_process											owl:Class	
GO:0050506	biolink:NamedThing	vomilenine glucosyltransferase activity	Catalysis of the reaction: UDP-D-glucose + vomilenine = H(+) + raucaffricine + UDP.	tmpzr1t_l9r_go_relaxed.owl	UDP-glucose:vomilenine 21-O-beta-D-glucosyltransferase activity|vomilenine-glucosyltransferase activity|UDPG:vomilenine 21-beta-D-glucosyltransferase activity|UDPG:vomilenine 21beta-D-glucosyltransferase activity				EC:2.4.1.219|RHEA:19385|KEGG_REACTION:R05882|MetaCyc:2.4.1.219-RXN									molecular_function											owl:Class	
GO:0035278	biolink:NamedThing	miRNA-mediated gene silencing by inhibition of translation	The process in which microRNAs (miRNAs) block the translation of target mRNAs into proteins. Once incorporated into a RNA-induced silencing complex (RISC), a miRNA will typically mediate repression of translation if the miRNA imperfectly base-pairs with the 3' untranslated regions of target mRNAs.	tmpzr1t_l9r_go_relaxed.owl	gene silencing by miRNA, negative regulation of translation|down-regulation of translation involved in gene silencing by miRNA|miRNA mediated inhibition of translation|downregulation of translation involved in gene silencing by miRNA|down regulation of translation involved in gene silencing by miRNA|inhibition of translation involved in gene silencing by miRNA|miRNA-mediated gene silencing, negative regulation of translation|negative regulation of translation involved in gene silencing by microRNA													biological_process											owl:Class	
GO:0035195	biolink:NamedThing	gene silencing by miRNA	Downregulation of gene expression through the action of microRNAs (miRNAs), endogenous 21-24 nucleotide small RNAs processed from stem-loop RNA precursors (pre-miRNAs). Once incorporated into a RNA-induced silencing complex (RISC), miRNAs can downregulate gene expression by either of two posttranscriptional mechanisms: endolytic cleavage of the RNA (often mRNA) or mRNA translational repression, usually accompanied by poly-A tail shortening and subsequent degradation of the mRNA.	tmpzr1t_l9r_go_relaxed.owl	gene silencing by microRNA|microRNA-mediated gene silencing|miRNA-mediated gene silencing													biological_process											owl:Class	
GO:0044340	biolink:NamedThing	canonical Wnt signaling pathway involved in regulation of cell proliferation	The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes that contributes to modulating the rate or frequency of cell proliferation.	tmpzr1t_l9r_go_relaxed.owl	canonical Wnt receptor signalling pathway involved in regulation of cell proliferation|canonical Wnt receptor signaling pathway involved in regulation of cell proliferation|canonical Wnt-activated signaling pathway involved in regulation of cell proliferation							jl	2010-08-20T03:57:25Z					biological_process											owl:Class	
GO:1902018	biolink:NamedThing	negative regulation of cilium assembly	Any process that stops, prevents or reduces the frequency, rate or extent of cilium assembly.	tmpzr1t_l9r_go_relaxed.owl	downregulation of ciliogenesis|downregulation of cilium biogenesis|down-regulation of cilium assembly|downregulation of cilium assembly|down regulation of cilium biogenesis|inhibition of cilium biogenesis|down regulation of cilium assembly|negative regulation of ciliogenesis|down-regulation of cilium biogenesis|negative regulation of cilium biogenesis|down-regulation of ciliogenesis|down regulation of ciliogenesis|inhibition of cilium assembly|inhibition of ciliogenesis							dph	2013-03-26T18:10:56Z					biological_process											owl:Class	
GO:2001228	biolink:NamedThing	regulation of response to gamma radiation	Any process that modulates the frequency, rate or extent of response to gamma radiation.	tmpzr1t_l9r_go_relaxed.owl	regulation of response to gamma ray|regulation of response to gamma-ray photon							yaf	2011-11-20T04:51:07Z					biological_process											owl:Class	
GO:0030852	biolink:NamedThing	regulation of granulocyte differentiation	Any process that modulates the frequency, rate or extent of granulocyte differentiation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0046664	biolink:NamedThing	dorsal closure, amnioserosa morphology change	The changes that occur during dorsal closure of the shape and structure of the amnioserosa, an epithelium that occupies the dorsal side of the embryo.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1904950	biolink:NamedThing	negative regulation of establishment of protein localization	Any process that stops, prevents or reduces the frequency, rate or extent of establishment of protein localization.	tmpzr1t_l9r_go_relaxed.owl	down regulation of protein recruitment|inhibition of protein recruitment|negative regulation of protein positioning|down regulation of establishment of protein localization|down regulation of establishment of protein localisation|down-regulation of protein positioning|down-regulation of protein recruitment|inhibition of establishment of protein localization|inhibition of establishment of protein localisation|down-regulation of establishment of protein localisation|negative regulation of protein recruitment|downregulation of establishment of protein localization|inhibition of protein positioning|down regulation of protein positioning|downregulation of protein positioning|downregulation of establishment of protein localisation|downregulation of protein recruitment|down-regulation of establishment of protein localization|negative regulation of establishment of protein localisation							mec	2016-02-05T09:59:24Z					biological_process											owl:Class	
GO:0010616	biolink:NamedThing	negative regulation of cardiac muscle adaptation	Any process that decreases the rate, extent or frequency of the process in which cardiac muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0019975	biolink:NamedThing	interleukin-17 binding	Binding to a member of the interleukin-17 family of cytokines.	tmpzr1t_l9r_go_relaxed.owl	IL-17 binding													molecular_function											owl:Class	
GO:0060650	biolink:NamedThing	epithelial cell proliferation involved in mammary gland bud elongation	The multiplication or reproduction of mammary gland bud epithelial cells, resulting in the elongation of the bud.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-05-29T08:54:54Z					biological_process											owl:Class	
GO:1904678	biolink:NamedThing	alpha-aminoacyl-tRNA binding	Binding to an alpha-aminoacyl-tRNA.	tmpzr1t_l9r_go_relaxed.owl	aminoacyl-tRNA binding							hjd	2015-09-18T16:44:17Z					molecular_function											owl:Class	
GO:0000923	biolink:NamedThing	equatorial microtubule organizing center	A microtubule organizing center formed by a band of gamma-tubulin that is recruited to a circumferential band of F-actin at the midpoint of a cell and which nucleates microtubules from the cell division site at the end of mitosis.	tmpzr1t_l9r_go_relaxed.owl	EMTOC|equatorial microtubule organising centre													cellular_component											owl:Class	
GO:0035313	biolink:NamedThing	wound healing, spreading of epidermal cells	The migration of an epidermal cell along or through a wound gap that contributes to the reestablishment of a continuous epidermis.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0044319	biolink:NamedThing	wound healing, spreading of cells	The migration of a cell along or through a wound gap that contributes to the reestablishment of a continuous surface.	tmpzr1t_l9r_go_relaxed.owl	cell migration involved in wound healing epiboly							jl	2010-07-14T02:10:01Z					biological_process											owl:Class	
GO:0015194	biolink:NamedThing	L-serine transmembrane transporter activity	Enables the transfer of L-serine from one side of a membrane to the other. L-serine is the L-enantiomer of 2-amino-3-hydroxypropanoic acid.	tmpzr1t_l9r_go_relaxed.owl	L-serine permease activity|threonine/serine:sodium symporter activity|L-serine transporter activity|serine transporter activity				Reactome:R-HSA-8932980							GO:1905361|GO:0015511		molecular_function											owl:Class	
GO:1901039	biolink:NamedThing	regulation of peptide antigen transport	Any process that modulates the frequency, rate or extent of peptide antigen transport.	tmpzr1t_l9r_go_relaxed.owl								bf	2012-06-22T04:07:56Z					biological_process											owl:Class	
GO:0002583	biolink:NamedThing	regulation of antigen processing and presentation of peptide antigen	Any process that modulates the frequency, rate, or extent of antigen processing and presentation of peptide antigen.	tmpzr1t_l9r_go_relaxed.owl	regulation of peptide antigen processing and presentation													biological_process											owl:Class	
GO:0007473	biolink:NamedThing	wing disc proximal/distal pattern formation	The establishment, maintenance and elaboration of the proximal/distal axis of the wing disc, a precursor to the adult wing.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0007449	biolink:NamedThing	proximal/distal pattern formation, imaginal disc	The establishment, maintenance and elaboration of the proximal/distal axis of the imaginal disc. Imaginal disks are masses of hypodermic cells, carried by the larvae of some insects after leaving the egg, from which masses the wings and legs of the adult are subsequently formed.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0106394	biolink:NamedThing	negative regulation of palmitic acid catabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of a palmitic acid catabolic process.	tmpzr1t_l9r_go_relaxed.owl								hjd	2021-10-08T15:25:47Z					biological_process											owl:Class	
GO:0106393	biolink:NamedThing	regulation of palmitic acid catabolic process	Any process that modulates the frequency, rate or extent of a palmitic acid catabolic process.	tmpzr1t_l9r_go_relaxed.owl								hjd	2021-10-08T15:17:05Z					biological_process											owl:Class	
GO:0003010	biolink:NamedThing	voluntary skeletal muscle contraction	A process in which force is generated within voluntary skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. In the voluntary skeletal muscle, the muscle contraction takes advantage of an ordered sarcomeric structure and it is under voluntary control. Voluntary skeletal muscle is skeletal muscle that is under conscious control.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0003009	biolink:NamedThing	skeletal muscle contraction	A process in which force is generated within skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. In the skeletal muscle, the muscle contraction takes advantage of an ordered sarcomeric structure and in most cases it is under voluntary control.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0090354	biolink:NamedThing	regulation of auxin metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving auxins, plant hormones that regulate aspects of plant growth.	tmpzr1t_l9r_go_relaxed.owl	regulation of auxin metabolism							tb	2010-06-29T01:51:18Z					biological_process											owl:Class	
GO:0042441	biolink:NamedThing	eye pigment metabolic process	The chemical reactions and pathways involving eye pigments, any general or particular coloring matter in living organisms, found or utilized in the eye.	tmpzr1t_l9r_go_relaxed.owl	eye pigment metabolism													biological_process											owl:Class	
GO:2000367	biolink:NamedThing	regulation of acrosomal vesicle exocytosis	Any process that modulates the frequency, rate or extent of acrosomal vesicle exocytosis.	tmpzr1t_l9r_go_relaxed.owl	regulation of acrosome exocytosis|regulation of acrosomal granule exocytosis							yaf	2011-02-07T11:52:34Z					biological_process											owl:Class	
GO:0017158	biolink:NamedThing	regulation of calcium ion-dependent exocytosis	Any process that modulates the frequency, rate or extent of calcium ion-dependent exocytosis.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0030987	biolink:NamedThing	high molecular weight kininogen receptor binding	Binding to a high molecular weight kininogen receptor.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0140702	biolink:NamedThing	cyclic GMP-AMP binding	Binding to cyclic GMP-AMP (cGAMP) nucleotide.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/21980						pg	2021-08-27T05:39:31Z					molecular_function											owl:Class	
GO:0032559	biolink:NamedThing	adenyl ribonucleotide binding	Binding to an adenyl ribonucleotide, any compound consisting of adenosine esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose moiety.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1901017	biolink:NamedThing	negative regulation of potassium ion transmembrane transporter activity	Any process that stops, prevents or reduces the frequency, rate or extent of potassium ion transmembrane transporter activity.	tmpzr1t_l9r_go_relaxed.owl	down regulation of potassium ion transmembrane transporter activity|downregulation of potassium transporter activity|downregulation of potassium ion transmembrane transporter activity|down-regulation of potassium transporter activity|inhibition of potassium ion transmembrane transporter activity|negative regulation of potassium transporter activity|inhibition of potassium transporter activity|down-regulation of potassium ion transmembrane transporter activity|down regulation of potassium transporter activity							rl	2012-06-15T01:14:10Z					biological_process											owl:Class	
GO:2001173	biolink:NamedThing	regulation of histone H2B conserved C-terminal lysine ubiquitination	Any process that modulates the frequency, rate or extent of histone H2B conserved C-terminal lysine ubiquitination.	tmpzr1t_l9r_go_relaxed.owl	regulation of fission yeast H2B K119 ubiquitination|regulation of mammalian H2B K120 ubiquitination|regulation of budding yeast H2B K123 ubiquitination							se	2011-10-29T06:28:47Z					biological_process											owl:Class	
GO:0010110	biolink:NamedThing	regulation of photosynthesis, dark reaction	Any process that modulates the frequency, rate or extent of photosynthesis dark reaction.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1902682	biolink:NamedThing	protein localization to pericentric heterochromatin	A process in which a protein is transported to, or maintained in the pericentric heterochromatin.	tmpzr1t_l9r_go_relaxed.owl	protein localisation in centromeric heterochromatin							mah	2014-02-05T16:59:30Z					biological_process											owl:Class	
GO:0097355	biolink:NamedThing	protein localization to heterochromatin	Any process in which a protein is transported to, or maintained at, a part of a chromosome that is organized into heterochromatin.	tmpzr1t_l9r_go_relaxed.owl	protein localisation to heterochromatin							pr	2012-07-03T03:19:07Z					biological_process											owl:Class	
GO:0001930	biolink:NamedThing	positive regulation of exocyst assembly	Any process that increases the rate or extent of exocyst assembly.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of exocyst assembly|upregulation of exocyst assembly|stimulation of exocyst assembly|up regulation of exocyst assembly|activation of exocyst assembly													biological_process											owl:Class	
GO:0015047	biolink:NamedThing	NADPH-cytochrome-c2 reductase activity	Catalysis of the reaction: NADPH + H+ + 2 ferricytochrome c2 = NADP+ + 2 ferrocytochrome c2.	tmpzr1t_l9r_go_relaxed.owl	cytochrome c2 reductase (reduced nicotinamide adinine dinucleotide phosphate, NADPH)|reductase, cytochrome c2 (reduced nicotinamide adenine dinucleotide phosphate)|NADPH:ferricytochrome-c2 oxidoreductase activity				RHEA:15237|EC:1.6.2.5|MetaCyc:NADPH--CYTOCHROME-C2-REDUCTASE-RXN									molecular_function											owl:Class	
GO:0016653	biolink:NamedThing	oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces a heme protein.	tmpzr1t_l9r_go_relaxed.owl	oxidoreductase activity, acting on NADH or NADPH, haem protein as acceptor|oxidoreductase activity, acting on NADH or NADPH, heme protein as acceptor				EC:1.6.2.-									molecular_function											owl:Class	
GO:0070195	biolink:NamedThing	growth hormone receptor complex	A receptor complex that consists of two identical subunits and binds growth hormone.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0043235	biolink:NamedThing	receptor complex	Any protein complex that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0005984	biolink:NamedThing	disaccharide metabolic process	The chemical reactions and pathways involving any disaccharide, sugars composed of two monosaccharide units.	tmpzr1t_l9r_go_relaxed.owl	disaccharide metabolism													biological_process											owl:Class	
GO:0046583	biolink:NamedThing	cation efflux transmembrane transporter activity	Enables the transfer of a cation or cations from the inside of the cell to the outside of the cell across a membrane.	tmpzr1t_l9r_go_relaxed.owl	cation efflux permease activity													molecular_function											owl:Class	
GO:0044513	biolink:NamedThing	envenomation resulting in modulation of G protein-coupled receptor activity in other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant modulation of G protein-coupled receptor activity in of the bitten organism.	tmpzr1t_l9r_go_relaxed.owl	envenomation resulting in modulation of G-protein coupled receptor activity in other organism							jl	2012-02-26T11:02:17Z					biological_process											owl:Class	
GO:1900750	biolink:NamedThing	oligopeptide binding	Binding to an oligopeptide.	tmpzr1t_l9r_go_relaxed.owl	Oligopeptid binding|oligopeptides binding|oligopeptido binding							jl	2012-05-29T02:13:31Z					molecular_function											owl:Class	
GO:0006997	biolink:NamedThing	nucleus organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nucleus.	tmpzr1t_l9r_go_relaxed.owl	nuclear organisation|nuclear organization and biogenesis|nuclear morphology|nucleus organization and biogenesis|nuclear organization											GO:0048287		biological_process											owl:Class	
GO:0004298	biolink:NamedThing	threonine-type endopeptidase activity	Catalysis of the hydrolysis of internal peptide bonds in a polypeptide chain by a mechanism in which the hydroxyl group of a threonine residue at the active center acts as a nucleophile.	tmpzr1t_l9r_go_relaxed.owl	large multicatalytic protease|tricorn protease|tricorn proteinase|proteasome endopeptidase complex|MCP|prosome|threonine endopeptidase activity|26S protease|multicatalytic proteinase (complex)|multicatalytic proteinase|ingensin|alkaline protease|multicatalytic endopeptidase complex|lens neutral proteinase				EC:3.4.25.-									molecular_function											owl:Class	
GO:0004175	biolink:NamedThing	endopeptidase activity	Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain.	tmpzr1t_l9r_go_relaxed.owl	endoprotease activity|elastase activity|proteinase|proteasome endopeptidase activity				Reactome:R-HSA-9008475|Reactome:R-HSA-8939801|Reactome:R-HSA-9010096|Reactome:R-HSA-1234159|Reactome:R-HSA-5668481|Reactome:R-HSA-6784676|Reactome:R-HSA-8866553|Reactome:R-HSA-174202|Reactome:R-HSA-5635854|Reactome:R-HSA-2213200|Reactome:R-HSA-9009362|Reactome:R-HSA-5635868|Reactome:R-HSA-5658430|Reactome:R-HSA-450466|Reactome:R-HSA-74730|Reactome:R-HSA-8934819|Reactome:R-HSA-187574|Reactome:R-HSA-180573|Reactome:R-HSA-5358460|Reactome:R-HSA-8854071|Reactome:R-HSA-8850992|Reactome:R-HSA-193682|Reactome:R-HSA-5668520|Reactome:R-HSA-4641256|Reactome:R-HSA-180603|Reactome:R-HSA-68825|Reactome:R-HSA-2130282|Reactome:R-HSA-8952408|Reactome:R-HSA-8957265|Reactome:R-HSA-1433374|MetaCyc:RXN0-5195|Reactome:R-HSA-9604642|Reactome:R-HSA-1236970|Reactome:R-HSA-5687112|Reactome:R-HSA-264458|Reactome:R-HSA-1236935|Reactome:R-HSA-5607731|Reactome:R-HSA-5358340|Reactome:R-HSA-8866858|Reactome:R-HSA-8852354|Reactome:R-HSA-5607724|Reactome:R-HSA-69016|Reactome:R-HSA-174255|Reactome:R-HSA-1168640|Reactome:R-HSA-1504193|Reactome:R-HSA-983158|Reactome:R-HSA-69600|Reactome:R-HSA-1251997|Reactome:R-HSA-174105|Reactome:R-HSA-3640874|Reactome:R-HSA-9008110|Reactome:R-HSA-4608855|Reactome:R-HSA-5387392|Reactome:R-HSA-75825|Reactome:R-HSA-209061|Reactome:R-HSA-188191|Reactome:R-HSA-5610760|Reactome:R-HSA-68948|Reactome:R-HSA-211715|Reactome:R-HSA-174203|Reactome:R-HSA-9614271|Reactome:R-HSA-5362448|Reactome:R-HSA-5610757|Reactome:R-HSA-353125|Reactome:R-HSA-5693081|Reactome:R-HSA-983150|Reactome:R-HSA-3928656|Reactome:R-HSA-5610758|Reactome:R-HSA-8854044|Reactome:R-HSA-8849797|Reactome:R-HSA-6784628|Reactome:R-HSA-174058|Reactome:R-HSA-9011313|Reactome:R-HSA-4641260|Reactome:R-HSA-5610754							GO:0016809		molecular_function											owl:Class	
GO:0072544	biolink:NamedThing	L-DOPA binding	Binding to L-DOPA, the modified amino acid (2S)-2-amino-3-(3,4-dihydroxyphenyl)propanoic acid.	tmpzr1t_l9r_go_relaxed.owl								mah	2011-01-19T05:40:04Z					molecular_function											owl:Class	
GO:0051513	biolink:NamedThing	regulation of monopolar cell growth	Any process that modulates the frequency, rate or extent of monopolar cell growth, polarized growth from one end of a cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0051510	biolink:NamedThing	regulation of unidimensional cell growth	Any process that modulates the frequency, rate or extent of unidimensional cell growth, the process in which a cell irreversibly increases in size in one [spatial] dimension or along one axis.	tmpzr1t_l9r_go_relaxed.owl	regulation of cell elongation													biological_process											owl:Class	
GO:0031856	biolink:NamedThing	parathyroid hormone receptor binding	Binding to a parathyroid hormone receptor.	tmpzr1t_l9r_go_relaxed.owl	parathyroid hormone receptor ligand													molecular_function											owl:Class	
GO:0047446	biolink:NamedThing	(1-hydroxycyclohexan-1-yl)acetyl-CoA lyase activity	Catalysis of the reaction: (1-hydroxycyclohexan-1-yl)acetyl-CoA = acetyl-CoA + cyclohexanone.	tmpzr1t_l9r_go_relaxed.owl	(1-hydroxycyclohexan-1-yl)acetyl-CoA cyclohexanone-lyase (acetyl-CoA-forming)|(1-hydroxycyclohexan-1-yl)acetyl-CoA cyclohexanone-lyase activity				RHEA:23868|MetaCyc:4.1.3.35-RXN|EC:4.1.3.35|KEGG_REACTION:R02232									molecular_function											owl:Class	
GO:1904933	biolink:NamedThing	regulation of cell proliferation in midbrain	Any process that modulates the frequency, rate or extent of cell proliferation in midbrain.	tmpzr1t_l9r_go_relaxed.owl	regulation of mesencepahalic cell proliferation|regulation of cell proliferation in mesencephalon							bf	2016-02-01T13:16:11Z					biological_process											owl:Class	
GO:0014703	biolink:NamedThing	oscillatory muscle contraction	A process in which force is generated within oscillatory skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. Oscillatory muscle contraction occurs in insect wing muscles and is characterized by asynchrony between action potential and contraction and by stretch activation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0060719	biolink:NamedThing	chorionic trophoblast cell development	The process whose specific outcome is the progression of the chorionic trophoblast over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-06-11T02:58:45Z					biological_process											owl:Class	
GO:0035984	biolink:NamedThing	cellular response to trichostatin A	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a trichostatin A stimulus.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-08-23T01:48:43Z					biological_process											owl:Class	
GO:0080166	biolink:NamedThing	stomium development	The process whose specific outcome is the progression of the stomium over time, from its formation to the mature structure. A stomium is a fissure or pore in the anther lobe through which the pollen is released.	tmpzr1t_l9r_go_relaxed.owl								dhl	2010-09-23T05:03:40Z					biological_process											owl:Class	
GO:0072761	biolink:NamedThing	cellular response to capsazepine	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a capsazepine stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2012-11-09T11:47:53Z					biological_process											owl:Class	
GO:0010362	biolink:NamedThing	negative regulation of anion channel activity by blue light	Any process in which blue light stops, prevents, or reduces the frequency, rate, or extent of the anion channel activity.	tmpzr1t_l9r_go_relaxed.owl	negative regulation by blue light of anion channel activity|inhibition by blue light of anion channel activity													biological_process											owl:Class	
GO:0010360	biolink:NamedThing	negative regulation of anion channel activity	Any process that stops, prevents, or reduces the frequency, rate, or extent of the anion channel activity.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0033053	biolink:NamedThing	D-glutamine metabolic process	The chemical reactions and pathways involving D-glutamine, the D-enantiomer of the amino acid glutamine, i.e. (2R)-2,5-diamino-5-oxopentanoic acid.	tmpzr1t_l9r_go_relaxed.owl	D-glutamine metabolism													biological_process											owl:Class	
GO:0046416	biolink:NamedThing	D-amino acid metabolic process	The chemical reactions and pathways involving D-amino acids, the D-enantiomers of amino acids.	tmpzr1t_l9r_go_relaxed.owl	D-amino acid metabolism													biological_process											owl:Class	
GO:0060080	biolink:NamedThing	inhibitory postsynaptic potential	A process that causes a temporary decrease in postsynaptic membrane potential due to the flow of negatively charged ions into the postsynaptic cell. The flow of ions that causes an IPSP is an inhibitory postsynaptic current (IPSC) and makes it more difficult for the neuron to fire an action potential.	tmpzr1t_l9r_go_relaxed.owl	IPSP|regulation of inhibitory post-synaptic membrane potential													biological_process											owl:Class	
GO:0086055	biolink:NamedThing	Purkinje myocyte to ventricular cardiac muscle cell communication by electrical coupling	The process that mediates signaling interactions between a Purkinje myocyte and a ventricular cardiac muscle cell by transfer of current between their adjacent cytoplasms via intercellular protein channels.	tmpzr1t_l9r_go_relaxed.owl								dph	2011-11-17T10:51:59Z					biological_process											owl:Class	
GO:0086068	biolink:NamedThing	Purkinje myocyte to ventricular cardiac muscle cell communication	The process that mediates interactions between a Purkinje myocyte and its surroundings that contributes to the process of the Purkinje myocyte communicating with a ventricular cardiac muscle cell in cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.	tmpzr1t_l9r_go_relaxed.owl								dph	2011-11-22T09:14:49Z					biological_process											owl:Class	
GO:0005662	biolink:NamedThing	DNA replication factor A complex	A conserved heterotrimeric complex that binds nonspecifically to single-stranded DNA and is required for multiple processes in eukaryotic DNA metabolism, including DNA replication, DNA repair, and recombination. In all eukaryotic organisms examined the complex is composed of subunits of approximately 70, 30, and 14 kDa.	tmpzr1t_l9r_go_relaxed.owl	RPA|replication protein A				Wikipedia:Replication_protein_A									cellular_component											owl:Class	
GO:0019991	biolink:NamedThing	septate junction assembly	The assembly of a septate junction, an intercellular junction found in invertebrate epithelia that is characterized by a ladder like appearance in electron micrographs and thought to provide structural strength and to provide a barrier to diffusion of solutes through the intercellular space.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0120192	biolink:NamedThing	tight junction assembly	A cellular process that results in the aggregation, arrangement and bonding together of a set of components to form a tight junction. A tight junction seals cells together in an epithelium in a way that prevents even small molecules from leaking from one side of the sheet to the other.	tmpzr1t_l9r_go_relaxed.owl	occluding junction assembly|occluding cell junction assembly							krc	2018-08-14T22:48:05Z					biological_process											owl:Class	
GO:1903521	biolink:NamedThing	positive regulation of mammary gland involution	Any process that activates or increases the frequency, rate or extent of mammary gland involution.	tmpzr1t_l9r_go_relaxed.owl	upregulation of mammary gland involution|activation of mammary gland involution|up-regulation of mammary gland involution|up regulation of mammary gland involution							dph	2014-10-06T12:01:39Z					biological_process											owl:Class	
GO:0010403	biolink:NamedThing	pectic arabinogalactan I metabolic process	The chemical reactions and pathways involving pectic arabinogalactan I, an alpha-(1,4)-linked D-galactopyranose backbone that is substituted with alpha-l-Araf residues via the O-3 of the D-galactose residues. Arabinogalactan I can be found as a side chain of rhamnogalacturonan I.	tmpzr1t_l9r_go_relaxed.owl	pectic arabinogalactan I metabolism													biological_process											owl:Class	
GO:0010400	biolink:NamedThing	rhamnogalacturonan I side chain metabolic process	The chemical reactions and pathways involving the side chains of the pectin, rhamnogalacturonan I.	tmpzr1t_l9r_go_relaxed.owl	rhamnogalacturonan I side chain metabolism													biological_process											owl:Class	
GO:0070739	biolink:NamedThing	protein-glutamic acid ligase activity	Catalysis of the posttranslational transfer of one or more glutamate residues to a specific residue on a target protein.	tmpzr1t_l9r_go_relaxed.owl	protein glutamylase activity|protein-glutamate ligase activity							mah	2009-06-19T02:23:22Z					molecular_function											owl:Class	
GO:1902722	biolink:NamedThing	positive regulation of prolactin secretion	Any process that activates or increases the frequency, rate or extent of prolactin secretion.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of prolactin secretion|upregulation of prolactin secretion|activation of prolactin secretion|up regulation of prolactin secretion							mr	2014-02-24T16:09:37Z					biological_process											owl:Class	
GO:2000300	biolink:NamedThing	regulation of synaptic vesicle exocytosis	Any process that modulates the frequency, rate or extent of synaptic vesicle exocytosis.	tmpzr1t_l9r_go_relaxed.owl								dph	2011-01-03T08:20:40Z					biological_process											owl:Class	
GO:0120097	biolink:NamedThing	glycosylphosphatidylinositol-mannosyltransferase II complex	A protein complex that is involved in the transfer of the second mannose to the glycosylphosphatidylinositol (GPI) during GPI precursor assembly. In yeast S. cerevisiae this complex consists of GPI18p and PGA1p.	tmpzr1t_l9r_go_relaxed.owl	GPI-MT-I complex							krc	2017-09-18T20:51:56Z					cellular_component											owl:Class	
GO:2001079	biolink:NamedThing	beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-D-Glc binding	Binding to beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-D-Glc.	tmpzr1t_l9r_go_relaxed.owl								jl	2011-09-15T01:15:19Z					molecular_function											owl:Class	
GO:0033596	biolink:NamedThing	TSC1-TSC2 complex	A protein complex consisting of at least tumerin and hamartin; its formation may regulate hamartin homomultimer formation. The complex acts as a GTPase activating protein (GAP) for the small GTPase (Rheb), and inhibits the TOR signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	tuberous sclerosis complex|tuberin-hamartin complex													cellular_component											owl:Class	
GO:0006054	biolink:NamedThing	N-acetylneuraminate metabolic process	The chemical reactions and pathways involving N-acetylneuraminate, the anion of 5-(acetylamino)-3,5-dideoxy-D-glycero-D-galacto-non-3-ulosonic acid.	tmpzr1t_l9r_go_relaxed.owl	sialic acid metabolic process|sialic acid metabolism|N-acetylneuraminate metabolism													biological_process											owl:Class	
GO:0051396	biolink:NamedThing	positive regulation of nerve growth factor receptor activity	Any process that activates or increases the frequency, rate or extent of the activity of the nerve growth factor (NGF) receptor.	tmpzr1t_l9r_go_relaxed.owl	stimulation of nerve growth factor receptor activity|upregulation of nerve growth factor receptor activity|positive regulation of NGF receptor activity|activation of nerve growth factor receptor activity|up-regulation of nerve growth factor receptor activity|up regulation of nerve growth factor receptor activity													biological_process											owl:Class	
GO:1905585	biolink:NamedThing	regulation of outer hair cell apoptotic process	Any process that modulates the frequency, rate or extent of outer hair cell apoptotic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of outer hair cell apoptosis|regulation of cochlear outer hair cell apoptosis|regulation of cochlear outer hair cell apoptotic process							sl	2016-10-24T22:35:34Z					biological_process											owl:Class	
GO:0000389	biolink:NamedThing	mRNA 3'-splice site recognition	Recognition of the intron 3'-splice site by components of the assembling U2- or U12-type spliceosome.	tmpzr1t_l9r_go_relaxed.owl	U2-type nuclear mRNA 3'-splice site recognition|nuclear mRNA 3'-splice site recognition|U12-type nuclear mRNA 3'-splice site recognition											GO:0000382|GO:0000383		biological_process											owl:Class	
GO:0102717	biolink:NamedThing	DIBOA-glucoside oxygenase activity	Catalysis of the reaction: DIBOA-beta-D-glucoside + O2 + 2-oxoglutarate <=> TRIBOA-beta-D-glucoside + succinate + carbon dioxide.	tmpzr1t_l9r_go_relaxed.owl					RHEA:32115|EC:1.14.11.59|MetaCyc:RXN-6685									molecular_function											owl:Class	
GO:0050498	biolink:NamedThing	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, with 2-oxoglutarate as one donor, and the other dehydrogenated	Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from 2-oxoglutarate and one other donor, and the latter donor is dehydrogenated.	tmpzr1t_l9r_go_relaxed.owl					EC:1.14.20.-									molecular_function											owl:Class	
GO:1904927	biolink:NamedThing	cellular response to palmitoleic acid	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a palmitoleic acid stimulus.	tmpzr1t_l9r_go_relaxed.owl								mr	2016-01-27T23:07:31Z					biological_process											owl:Class	
GO:1900123	biolink:NamedThing	regulation of nodal receptor complex assembly	Any process that modulates the frequency, rate or extent of nodal receptor complex assembly.	tmpzr1t_l9r_go_relaxed.owl	regulation of nodal receptor complex formation|regulation of ActRIIB.ALK4.EGF-CFC complex formation							bf	2012-02-22T04:21:49Z					biological_process											owl:Class	
GO:1902287	biolink:NamedThing	semaphorin-plexin signaling pathway involved in axon guidance	Any semaphorin-plexin signaling pathway that is involved in axon guidance.	tmpzr1t_l9r_go_relaxed.owl	semaphorin-plexin signalling pathway involved in axon growth cone guidance|semaphorin-plexin signalling pathway involved in axon pathfinding|semaphorin-plexin signalling pathway involved in axon chemotaxis|semaphorin-plexin signalling pathway involved in axon guidance|semaphorin-plexin signaling pathway involved in axon pathfinding|semaphorin-plexin signaling pathway involved in axon growth cone guidance|semaphorin-plexin signaling pathway involved in axon chemotaxis							pr	2013-07-08T16:07:03Z					biological_process											owl:Class	
GO:0071526	biolink:NamedThing	semaphorin-plexin signaling pathway	A series of molecular signals generated as a consequence of a semaphorin receptor (composed of a plexin and a neurophilin) binding to a semaphorin ligand.	tmpzr1t_l9r_go_relaxed.owl	semaphorin-plexin signalling pathway							mah	2010-01-07T03:48:07Z					biological_process											owl:Class	
GO:0009446	biolink:NamedThing	putrescine biosynthetic process	The chemical reactions and pathways resulting in the formation of putrescine, 1,4-diaminobutane; putrescine can be synthesized from arginine or ornithine and is the metabolic precursor of spermidine and spermine.	tmpzr1t_l9r_go_relaxed.owl	putrescine biosynthesis|putrescine synthesis|putrescine anabolism|putrescine formation													biological_process											owl:Class	
GO:2000851	biolink:NamedThing	positive regulation of glucocorticoid secretion	Any process that activates or increases the frequency, rate or extent of glucocorticoid secretion.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-07-26T08:44:51Z					biological_process											owl:Class	
GO:0042727	biolink:NamedThing	flavin-containing compound biosynthetic process	The chemical reactions and pathways resulting in the formation of a flavin, any derivative of the dimethylisoalloxazine (7,8-dimethylbenzo[g]pteridine-2,4(3H,10H)-dione) skeleton, with a substituent on the 10 position.	tmpzr1t_l9r_go_relaxed.owl	flavin-containing compound formation|riboflavin and derivative biosynthesis|vitamin B2 and derivative biosynthesis|vitamin B2 and derivative biosynthetic process|flavin-containing compound anabolism|riboflavin and derivative biosynthetic process|flavin-containing compound biosynthesis|flavin-containing compound synthesis													biological_process											owl:Class	
GO:0046497	biolink:NamedThing	nicotinate nucleotide metabolic process	The chemical reactions and pathways involving nicotinamide nucleotides, any nucleotide that contains combined nicotinate (pyridine 3-carboxylic acid, or niacin).	tmpzr1t_l9r_go_relaxed.owl	nicotinate nucleotide metabolism													biological_process											owl:Class	
GO:0019362	biolink:NamedThing	pyridine nucleotide metabolic process	The chemical reactions and pathways involving a pyridine nucleotide, a nucleotide characterized by a pyridine derivative as a nitrogen base.	tmpzr1t_l9r_go_relaxed.owl	pyridine nucleotide metabolism													biological_process											owl:Class	
GO:0051511	biolink:NamedThing	negative regulation of unidimensional cell growth	Any process that stops, prevents, or reduces the frequency, rate or extent of unidimensional cell growth, the process in which a cell irreversibly increases in size in one [spatial] dimension or along one axis.	tmpzr1t_l9r_go_relaxed.owl	downregulation of unidimensional cell growth|down regulation of unidimensional cell growth|down-regulation of unidimensional cell growth|negative regulation of cell elongation|inhibition of unidimensional cell growth													biological_process											owl:Class	
GO:0009943	biolink:NamedThing	adaxial/abaxial axis specification	The establishment, maintenance and elaboration of the adaxial / abaxial axis. Adaxial refers to being situated toward an axis of an anatomical structure. Abaxial refers to being situated away from an axis of an anatomical structure.	tmpzr1t_l9r_go_relaxed.owl	adaxial/abaxial determination													biological_process											owl:Class	
GO:1905351	biolink:NamedThing	pericyte cell migration	The orderly movement of a pericyte cell from one site to another.	tmpzr1t_l9r_go_relaxed.owl								rph	2016-08-05T12:01:48Z					biological_process											owl:Class	
GO:1901529	biolink:NamedThing	positive regulation of anion channel activity	Any process that activates or increases the frequency, rate or extent of anion channel activity.	tmpzr1t_l9r_go_relaxed.owl	upregulation of anion channel activity|up-regulation of anion channel activity|up regulation of anion channel activity|activation of anion channel activity							tb	2012-10-23T23:38:50Z					biological_process											owl:Class	
GO:0008139	biolink:NamedThing	nuclear localization sequence binding	Binding to a nuclear localization sequence, a specific peptide sequence that acts as a signal to localize the protein within the nucleus.	tmpzr1t_l9r_go_relaxed.owl	nuclear localisation sequence binding|nuclear localization signal binding|NLS binding													molecular_function											owl:Class	
GO:0150078	biolink:NamedThing	positive regulation of neuroinflammatory response	Any process that activates or increases the frequency, rate or extent of neuroinflammatory response.	tmpzr1t_l9r_go_relaxed.owl								bc	2018-07-26T12:35:50Z					biological_process											owl:Class	
GO:1900562	biolink:NamedThing	dehydroaustinol catabolic process	The chemical reactions and pathways resulting in the breakdown of dehydroaustinol.	tmpzr1t_l9r_go_relaxed.owl	dehydroaustinol degradation|dehydroaustinol breakdown|dehydroaustinol catabolism							di	2012-05-15T06:27:55Z					biological_process											owl:Class	
GO:0050185	biolink:NamedThing	phosphatidylinositol deacylase activity	Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol + H(2)O = 1-acyl-sn-glycero-3-phospho-D-myo-inositol + a carboxylate + H(+).	tmpzr1t_l9r_go_relaxed.owl	1-phosphatidyl-D-myo-inositol 2-acylhydrolase activity|phosphatidylinositol phospholipase A2 activity				KEGG_REACTION:R03360|MetaCyc:PHOSPHATIDYLINOSITOL-DEACYLASE-RXN|EC:3.1.1.52|RHEA:18001									molecular_function											owl:Class	
GO:0014868	biolink:NamedThing	cross bridge cycling involved in regulation of the velocity of shortening in skeletal muscle contraction	A process in which cross bridges are broken and reformed during filament sliding as part of the regulation of the velocity of shortening in skeletal muscle contraction.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0014880	biolink:NamedThing	regulation of muscle filament sliding involved in regulation of the velocity of shortening in skeletal muscle contraction	Any process that modulates the frequency, rate or extent of muscle filament sliding, and consequently contributes to the regulation of the velocity of shortening of skeletal muscle contraction.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0043547	biolink:NamedThing	positive regulation of GTPase activity	Any process that activates or increases the activity of a GTPase.	tmpzr1t_l9r_go_relaxed.owl	stimulation of Ran GTPase activity|up-regulation of Cdc42 GTPase activity|up-regulation of Rho GTPase activity|upregulation of Ran GTPase activity|up-regulation of Rab GTPase activity|stimulation of ARF GTPase activity|stimulation of Rho GTPase activity|up-regulation of Ran GTPase activity|up-regulation of Ras GTPase activity|up regulation of Rab GTPase activity|up regulation of Rap GTPase activity|upregulation of GTPase activity|upregulation of Cdc42 GTPase activity|stimulation of Cdc42 GTPase activity|positive regulation of Ral GTPase activity|stimulation of GTPase activity|up regulation of GTPase activity|stimulation of Rab GTPase activity|upregulation of Rab GTPase activity|positive regulation of ARF GTPase activity|positive regulation of Rab GTPase activity|up-regulation of Ral GTPase activity|up regulation of Ras GTPase activity|positive regulation of Rho GTPase activity|up-regulation of GTPase activity|stimulation of Rap GTPase activity|upregulation of Rho GTPase activity|positive regulation of Ras GTPase activity|upregulation of ARF GTPase activity|up-regulation of Rac GTPase activity|up-regulation of Rap GTPase activity|up-regulation of ARF GTPase activity|up regulation of Rho GTPase activity|upregulation of Ras GTPase activity|positive regulation of Ran GTPase activity|up regulation of Ral GTPase activity|stimulation of Ral GTPase activity|activation of GTPase activity|positive regulation of Cdc42 GTPase activity|stimulation of Rac GTPase activity|up regulation of ARF GTPase activity|positive regulation of Rac GTPase activity|positive regulation of Rap GTPase activity|up regulation of Ran GTPase activity|upregulation of Rap GTPase activity|upregulation of Rac GTPase activity|up regulation of Cdc42 GTPase activity|upregulation of Ral GTPase activity|stimulation of Ras GTPase activity|up regulation of Rac GTPase activity											GO:0032321|GO:0032851|GO:0032855|GO:0032320|GO:0032850|GO:0043089|GO:0032852|GO:0032854|GO:0032853		biological_process											owl:Class	
GO:0140443	biolink:NamedThing	mitochondrion-plasma membrane adaptor activity	The binding activity of a molecule that brings together a mitochondrion and a plasma membrane either via membrane lipid binding or by interacting with a mitochondrial outer membrane protein, to establish or maintain the localization of the mitochondrion.	tmpzr1t_l9r_go_relaxed.owl	mitochondrion plasma membrane tether activity|mitochondrion plasma membrane adaptor activity|plasma membrane-mitochondrion tether activity|plasma membrane-mitochondrion adaptor activity	https://github.com/geneontology/go-ontology/pull/19140						pg	2020-03-24T13:11:20Z					molecular_function											owl:Class	
GO:0030055	biolink:NamedThing	cell-substrate junction	A cell junction that forms a connection between a cell and the extracellular matrix.	tmpzr1t_l9r_go_relaxed.owl	cell-matrix junction													cellular_component											owl:Class	
GO:0070161	biolink:NamedThing	anchoring junction	A cell junction that mechanically attaches a cell (and its cytoskeleton) to neighboring cells or to the extracellular matrix.	tmpzr1t_l9r_go_relaxed.owl	anchoring cell junction													cellular_component											owl:Class	
GO:0072211	biolink:NamedThing	metanephric pyramids development	The process whose specific outcome is the progression of the metanephric pyramids over time, from their formation to the mature structures. Metanephric pyramids are the conical masses that constitute the renal medulla in a metanephros; they contain the loops of Henle and the medullary collecting ducts.	tmpzr1t_l9r_go_relaxed.owl	metanephric kidney pyramid development|metanephric pyramid development|metanephric renal medulla development|metanephric renal pyramid development							mah	2010-03-18T01:04:51Z					biological_process											owl:Class	
GO:0050998	biolink:NamedThing	nitric-oxide synthase binding	Binding to nitric-oxide synthase.	tmpzr1t_l9r_go_relaxed.owl	NOS binding													molecular_function											owl:Class	
GO:1901697	biolink:NamedThing	olivetolic acid biosynthetic process	The chemical reactions and pathways resulting in the formation of olivetolic acid.	tmpzr1t_l9r_go_relaxed.owl	olivetolic acid formation|olivetolic acid biosynthesis|olivetolic acid synthesis|olivetolic acid anabolism							ms	2012-12-13T08:07:51Z					biological_process											owl:Class	
GO:2000933	biolink:NamedThing	regulation of cellotriose metabolic process	Any process that modulates the frequency, rate or extent of cellotriose metabolic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of cellotriose metabolism							tt	2011-08-01T12:44:15Z					biological_process											owl:Class	
GO:0060253	biolink:NamedThing	negative regulation of glial cell proliferation	Any process that stops or decreases the rate or extent of glial cell proliferation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0019258	biolink:NamedThing	4-nitrotoluene catabolic process	The chemical reactions and pathways resulting in the breakdown of 4-nitrotoluene, 1-methyl-4-nitrobenzene.	tmpzr1t_l9r_go_relaxed.owl	4NT catabolic process|4-nitrotoluene breakdown|4-nitrotoluene catabolism|4-nitrotoluene degradation|4NT catabolism				MetaCyc:P421-PWY									biological_process											owl:Class	
GO:0019257	biolink:NamedThing	4-nitrotoluene metabolic process	The chemical reactions and pathways involving 4-nitrotoluene, 1-methyl-4-nitrobenzene. It is a light yellow liquid with a weak aromatic odor.	tmpzr1t_l9r_go_relaxed.owl	4-nitrotoluene metabolism|4NT metabolic process|4NT metabolism													biological_process											owl:Class	
GO:0002652	biolink:NamedThing	regulation of tolerance induction dependent upon immune response	Any process that modulates the frequency, rate, or extent of tolerance induction dependent upon immune response.	tmpzr1t_l9r_go_relaxed.owl	regulation of immune response-dependent tolerance induction													biological_process											owl:Class	
GO:0021980	biolink:NamedThing	subpallium cell migration	The orderly movement of cells from one site to another in the subpallium.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0003986	biolink:NamedThing	acetyl-CoA hydrolase activity	Catalysis of the reaction: acetyl-CoA + H(2)O = acetate + CoA + H(+).	tmpzr1t_l9r_go_relaxed.owl	acetyl-CoA deacylase activity|acetyl coenzyme A acylase activity|acetyl coenzyme A deacylase activity|acetyl-CoA thiol esterase activity|acetyl coenzyme A hydrolase activity|acetyl-CoA acylase activity				Reactome:R-HSA-390304|KEGG_REACTION:R00227|MetaCyc:ACETYL-COA-HYDROLASE-RXN|Reactome:R-HSA-2066779|RHEA:20289|EC:3.1.2.1									molecular_function											owl:Class	
GO:0051961	biolink:NamedThing	negative regulation of nervous system development	Any process that stops, prevents, or reduces the frequency, rate or extent of nervous system development, the origin and formation of nervous tissue.	tmpzr1t_l9r_go_relaxed.owl	inhibition of nervous system development|down-regulation of nervous system development|down regulation of nervous system development|downregulation of nervous system development													biological_process											owl:Class	
GO:1903721	biolink:NamedThing	positive regulation of I-kappaB phosphorylation	Any process that activates or increases the frequency, rate or extent of I-kappaB phosphorylation.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of IKB phosphorylation|activation of IkappaB phosphorylation|activation of I-kappaB phosphorylation|positive regulation of IkappaB phosphorylation|upregulation of IkappaB phosphorylation|activation of inhibitor of kappaB phosphorylation|up regulation of inhibitor of kappaB phosphorylation|activation of IKB phosphorylation|up-regulation of inhibitor of kappaB phosphorylation|up regulation of IKB phosphorylation|positive regulation of inhibitor of kappaB phosphorylation|up regulation of I-kappaB phosphorylation|upregulation of inhibitor of NF-kappaB phosphorylation|upregulation of inhibitor of kappaB phosphorylation|upregulation of IKB phosphorylation|up-regulation of inhibitor of NF-kappaB phosphorylation|up-regulation of IkappaB phosphorylation|up-regulation of I-kappaB phosphorylation|activation of inhibitor of NF-kappaB phosphorylation|positive regulation of IKB phosphorylation|upregulation of I-kappaB phosphorylation|up regulation of IkappaB phosphorylation|up regulation of inhibitor of NF-kappaB phosphorylation|positive regulation of inhibitor of NF-kappaB phosphorylation							lb	2014-12-08T15:45:25Z					biological_process											owl:Class	
GO:1903719	biolink:NamedThing	regulation of I-kappaB phosphorylation	Any process that modulates the frequency, rate or extent of I-kappaB phosphorylation.	tmpzr1t_l9r_go_relaxed.owl	regulation of inhibitor of NF-kappaB phosphorylation|regulation of inhibitor of kappaB phosphorylation|regulation of IKB phosphorylation|regulation of IkappaB phosphorylation							lb	2014-12-08T15:45:07Z					biological_process											owl:Class	
GO:1902230	biolink:NamedThing	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage	Any process that stops, prevents or reduces the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to DNA damage.	tmpzr1t_l9r_go_relaxed.owl	inhibition of DNA damage response, signal transduction resulting in induction of apoptosis|down regulation of intrinsic apoptotic signaling pathway in response to DNA damage|inhibition of intrinsic apoptotic signaling pathway in response to DNA damage|down-regulation of DNA damage response, signal transduction resulting in induction of apoptosis|downregulation of intrinsic apoptotic signaling pathway in response to DNA damage|downregulation of DNA damage response, signal transduction resulting in induction of apoptosis|negative regulation of DNA damage response, signal transduction resulting in induction of apoptosis|down regulation of DNA damage response, signal transduction resulting in induction of apoptosis|down-regulation of intrinsic apoptotic signaling pathway in response to DNA damage							rl	2013-06-14T09:39:58Z					biological_process											owl:Class	
GO:0044507	biolink:NamedThing	positive regulation of receptor activity in other organism	A process that activates or increases the frequency, rate or extent of the activity of a receptor in a second organism.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-02-23T04:31:52Z					biological_process											owl:Class	
GO:0002335	biolink:NamedThing	mature B cell differentiation	The process in which transitional stage B cells acquire the specialized features of mature B cells in the spleen.	tmpzr1t_l9r_go_relaxed.owl	mature B-cell differentiation|mature cell development|mature B lymphocyte differentiation|mature B-lymphocyte differentiation					Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.								biological_process											owl:Class	
GO:0120303	biolink:NamedThing	visually-mediated background adaptation	Any process in which an organism changes its pigmentation (lightening in response to a brighter environment or darkening in response to a dimmer environment) in response to a change in light intensity detected by melanopsin-expressing eye cells.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/20524						krc	2021-02-09T18:35:11Z					biological_process											owl:Class	
GO:1901184	biolink:NamedThing	regulation of ERBB signaling pathway	Any process that modulates the frequency, rate or extent of ERBB signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	regulation of EGF receptor family signaling pathway|regulation of ErbB signaling|regulation of ERBB signalling pathway|regulation of EGFR family signaling pathway							rl	2012-07-24T07:37:11Z					biological_process											owl:Class	
GO:0048784	biolink:NamedThing	pigment biosynthetic process involved in pigment granule maturation	The chemical reactions and pathways resulting in the formation of a pigment, contributing to the process in which a membrane-bounded organelle develops into a pigment granule. Maturation is a developmental process, independent of morphogenetic (shape) change, that is required for a cell or structure to attain its fully functional state.	tmpzr1t_l9r_go_relaxed.owl	pigment biosynthetic process during pigment granule maturation													biological_process											owl:Class	
GO:0102797	biolink:NamedThing	geranial:oxygen oxidoreductase activity	Catalysis of the reaction: geranial + O2 + H2O = H+ + geranate + hydrogen peroxide.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-8093|EC:1.2.3.1									molecular_function											owl:Class	
GO:1904299	biolink:NamedThing	negative regulation of transcytosis	Any process that stops, prevents or reduces the frequency, rate or extent of transcytosis.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of transcytosis|down regulation of transcytosis|downregulation of transcytosis|inhibition of transcytosis							sl	2015-06-09T22:53:32Z					biological_process											owl:Class	
GO:0010340	biolink:NamedThing	carboxyl-O-methyltransferase activity	Catalysis of the transfer of a methyl group to the carboxyl group of an acceptor molecule to form a methyl ester.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1900353	biolink:NamedThing	positive regulation of methanofuran biosynthetic process	Any process that activates or increases the frequency, rate or extent of methanofuran biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	up regulation of methanofuran biosynthesis|activation of methanofuran biosynthetic process|positive regulation of methanofuran biosynthesis|upregulation of methanofuran biosynthetic process|upregulation of methanofuran biosynthesis|up regulation of methanofuran biosynthetic process|activation of methanofuran biosynthesis|up-regulation of methanofuran biosynthesis|up-regulation of methanofuran biosynthetic process							tt	2012-04-06T02:14:09Z					biological_process											owl:Class	
GO:1900351	biolink:NamedThing	regulation of methanofuran biosynthetic process	Any process that modulates the frequency, rate or extent of methanofuran biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of methanofuran biosynthesis							tt	2012-04-06T02:13:51Z					biological_process											owl:Class	
GO:0043246	biolink:NamedThing	megasome	Large, cysteine proteinase rich lysosomes, often found in the amastigote (an intracytoplasmic, nonflagellated form of the parasite) stage of Leishmania species belonging to the mexicana complex.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0047624	biolink:NamedThing	adenosine-tetraphosphatase activity	Catalysis of the reaction: adenosine 5'-tetraphosphate + H2O = ATP + phosphate.	tmpzr1t_l9r_go_relaxed.owl	adenosine-tetraphosphate phosphohydrolase activity				MetaCyc:ADENOSINE-TETRAPHOSPHATASE-RXN|RHEA:24500|EC:3.6.1.14									molecular_function											owl:Class	
GO:0003217	biolink:NamedThing	cardiac right atrium formation	The developmental process pertaining to the initial formation of a cardiac right atrium from unspecified parts.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-10-13T09:53:12Z					biological_process											owl:Class	
GO:0003210	biolink:NamedThing	cardiac atrium formation	The developmental process pertaining to the initial formation of a cardiac atrium from unspecified parts. A cardiac atrium receives blood from a vein and pumps it to a cardiac ventricle.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-10-13T09:44:25Z					biological_process											owl:Class	
GO:0080136	biolink:NamedThing	priming of cellular response to stress	The process that enables cells to respond in a more rapid and robust manner than nonprimed cells to much lower levels of a stimulus indicating the organism is under stress.	tmpzr1t_l9r_go_relaxed.owl	priming of response to stress|priming of stress response							dhl	2009-05-06T05:05:15Z					biological_process											owl:Class	
GO:1990377	biolink:NamedThing	organomineral extracellular matrix	An extracellular matrix consisting of a densely packed organomineral assembly in which the mineral phase represents the majority of the material by weight.	tmpzr1t_l9r_go_relaxed.owl						An example is found in shell calcitic prisms of the Mediterranean fan mussel Pinna nobilis (PMID:15994301), but the term may also be useful to annotate bone and eggshell proteins.		pr	2014-05-07T10:02:28Z					cellular_component											owl:Class	
GO:0002323	biolink:NamedThing	natural killer cell activation involved in immune response	The change in morphology and behavior of a natural killer cell resulting from exposure a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response.	tmpzr1t_l9r_go_relaxed.owl	natural killer cell activation during immune response|NK cell activation during immune response													biological_process											owl:Class	
GO:0052018	biolink:NamedThing	modulation by symbiont of RNA levels in host	The alteration by an organism of the levels of RNA in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	modulation by symbiont of host RNA levels													biological_process											owl:Class	
GO:0102056	biolink:NamedThing	11-hydroxyjasmonate sulfotransferase activity	Catalysis of the reaction: 3'-phosphonato-5'-adenylyl sulfate + an 11-hydroxyjasmonate <=> adenosine 3',5'-bismonophosphate + H+ + an 11-hydroxyjasmonate sulfate.	tmpzr1t_l9r_go_relaxed.owl					RHEA:52732|MetaCyc:RXN-10453|EC:2.8.2.39									molecular_function											owl:Class	
GO:1900782	biolink:NamedThing	fumiquinazoline F metabolic process	The chemical reactions and pathways involving fumiquinazoline F.	tmpzr1t_l9r_go_relaxed.owl	fumiquinazoline F metabolism							di	2012-06-04T09:31:06Z					biological_process											owl:Class	
GO:0033249	biolink:NamedThing	positive regulation of penicillin catabolic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of any antibiotic that contains the condensed beta-lactamthiazolidine ring system.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of penicillin breakdown|positive regulation of penicillin catabolism|positive regulation of penicillin degradation													biological_process											owl:Class	
GO:1900307	biolink:NamedThing	negative regulation of maltoheptaose transport	Any process that stops, prevents or reduces the frequency, rate or extent of maltoheptaose transport.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of maltoheptaose transport|down regulation of maltoheptaose transport|inhibition of maltoheptaose transport|downregulation of maltoheptaose transport							tt	2012-04-05T07:58:27Z					biological_process											owl:Class	
GO:0005469	biolink:NamedThing	succinate:fumarate antiporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: succinate(out) + fumarate(in) = succinate(in) + fumarate(out).	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0015141	biolink:NamedThing	succinate transmembrane transporter activity	Enables the transfer of succinate, the dianion of ethane dicarboxylic acid, from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	dicarboxylate (succinate/fumarate/malate) antiporter activity													molecular_function											owl:Class	
GO:0045957	biolink:NamedThing	negative regulation of complement activation, alternative pathway	Any process that stops, prevents, or reduces the frequency, rate or extent of complement activation by the alternative pathway.	tmpzr1t_l9r_go_relaxed.owl	downregulation of complement activation, alternative pathway|down-regulation of complement activation, alternative pathway|down regulation of complement activation, alternative pathway|negative regulation of complement cascade, alternative pathway|inhibition of complement activation, alternative pathway													biological_process											owl:Class	
GO:0044097	biolink:NamedThing	secretion by the type IV secretion system	The controlled release of proteins or DNA by a cell, via the type IV secretion system.	tmpzr1t_l9r_go_relaxed.owl	secretion via the type IV secretion system							jl	2009-06-09T02:20:34Z					biological_process											owl:Class	
GO:0045698	biolink:NamedThing	negative regulation of synergid differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of synergid cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of synergid differentiation|downregulation of synergid differentiation|down regulation of synergid differentiation|negative regulation of synergid cell differentiation|inhibition of synergid differentiation													biological_process											owl:Class	
GO:0031419	biolink:NamedThing	cobalamin binding	Binding to cobalamin (vitamin B12), a water-soluble vitamin characterized by possession of a corrin nucleus containing a cobalt atom.	tmpzr1t_l9r_go_relaxed.owl	vitamin B12 binding													molecular_function											owl:Class	
GO:0043899	biolink:NamedThing	phosphoserine:homoserine phosphotransferase activity	Catalysis of the transfer of a phosphoryl group from phosphoserine to homoserine to form phosphohomoserine.	tmpzr1t_l9r_go_relaxed.owl	thrH													molecular_function											owl:Class	
GO:1902848	biolink:NamedThing	negative regulation of neuronal signal transduction	Any process that stops, prevents or reduces the frequency, rate or extent of neuronal signal transduction.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of neuronal signal transduction|inhibition of neuronal signal transduction|downregulation of neuronal signal transduction|down regulation of neuronal signal transduction							sjp	2014-04-02T10:11:18Z					biological_process											owl:Class	
GO:0102305	biolink:NamedThing	(13E)-labda-7,13-dien-15-ol synthase activity	Catalysis of the reaction: 2-cis,6-trans,10-trans-geranylgeranyl diphosphate + H2O <=> (13E)-labda-7,13-dien-15-ol + diphosphoric acid.	tmpzr1t_l9r_go_relaxed.owl					EC:3.1.7.10|RHEA:32075|MetaCyc:RXN-12892									molecular_function											owl:Class	
GO:0016794	biolink:NamedThing	diphosphoric monoester hydrolase activity	Catalysis of the hydrolysis of a diphosphoester to give a diphosphate group and a free hydroxyl group.	tmpzr1t_l9r_go_relaxed.owl					EC:3.1.7.-									molecular_function											owl:Class	
GO:0044859	biolink:NamedThing	protein insertion into plasma membrane raft	The process in which a protein is incorporated into a plasma membrane raft.	tmpzr1t_l9r_go_relaxed.owl								jl	2014-07-23T16:23:20Z					biological_process											owl:Class	
GO:0046485	biolink:NamedThing	ether lipid metabolic process	The chemical reactions and pathways involving ether lipids, lipids that contain (normally) one lipid alcohol in ether linkage to one of the carbon atoms (normally C-1) of glycerol.	tmpzr1t_l9r_go_relaxed.owl	ether lipid metabolism|plasmalogen metabolic process				Wikipedia:Ether_lipid									biological_process											owl:Class	
GO:1901979	biolink:NamedThing	regulation of inward rectifier potassium channel activity	Any process that modulates the frequency, rate or extent of inward rectifier potassium channel activity.	tmpzr1t_l9r_go_relaxed.owl	regulation of Kir channel activity							tb	2013-03-12T18:21:12Z					biological_process											owl:Class	
GO:0050400	biolink:NamedThing	xylitol kinase activity	Catalysis of the reaction: ATP + xylitol = ADP + 2 H(+) + xylitol 5-phosphate.	tmpzr1t_l9r_go_relaxed.owl	xylitol phosphotransferase activity|ATP:xylitol 5-phosphotransferase activity				KEGG_REACTION:R02136|MetaCyc:XYLITOL-KINASE-RXN|EC:2.7.1.122|RHEA:20209									molecular_function											owl:Class	
GO:0048694	biolink:NamedThing	positive regulation of collateral sprouting of injured axon	Any process that activates, maintains or increases the rate of collateral sprouting of an injured axon.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of collateral sprouting of injured axon|up regulation of collateral sprouting of injured axon|upregulation of collateral sprouting of injured axon|stimulation of collateral sprouting of injured axon|activation of collateral sprouting of injured axon													biological_process											owl:Class	
GO:0030091	biolink:NamedThing	protein repair	The process of restoring a protein to its original state after damage by such things as oxidation or spontaneous decomposition of residues.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0097212	biolink:NamedThing	lysosomal membrane organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lysosomal membrane. A lysosomal membrane is the lipid bilayer surrounding the lysosome and separating its contents from the cell cytoplasm.	tmpzr1t_l9r_go_relaxed.owl	lysosomal membrane organisation|lysosome membrane organization							pr	2012-01-12T10:16:15Z					biological_process											owl:Class	
GO:0032125	biolink:NamedThing	micronucleus organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the micronucleus.	tmpzr1t_l9r_go_relaxed.owl	micronuclear organization|micronuclear organization and biogenesis|micronucleus organisation													biological_process											owl:Class	
GO:0046438	biolink:NamedThing	D-cysteine metabolic process	The chemical reactions and pathways involving D-cysteine, (S)-2-amino-3-mercaptopropanoic acid, which occurs naturally in firefly luciferin.	tmpzr1t_l9r_go_relaxed.owl	D-cysteine metabolism													biological_process											owl:Class	
GO:0005657	biolink:NamedThing	replication fork	The Y-shaped region of a replicating DNA molecule, resulting from the separation of the DNA strands and in which the synthesis of new strands takes place. Also includes associated protein complexes.	tmpzr1t_l9r_go_relaxed.owl	replication focus				Wikipedia:Replication_fork									cellular_component											owl:Class	
GO:0036200	biolink:NamedThing	3-ketosteroid 9-alpha-monooxygenase activity	Catalysis of the reaction: androsta-1,4-diene-3,17-dione + NADH + H+ + O2 = 9alpha-hydroxyandrosta-1,4-diene-3,17-dione + NAD+ + H2O.	tmpzr1t_l9r_go_relaxed.owl	3-ketosteroid 9alpha-hydroxylase activity|KshAB activity				EC:1.14.15.30|KEGG_REACTION:R09860|RHEA:32199			bf	2012-04-20T02:09:47Z					molecular_function											owl:Class	
GO:0042164	biolink:NamedThing	interleukin-12 alpha subunit binding	Binding to the alpha subunit of interleukin-12.	tmpzr1t_l9r_go_relaxed.owl	CLMFp35 binding|IL-12A binding|IL-12p35 binding|NKSFp35 binding													molecular_function											owl:Class	
GO:0031122	biolink:NamedThing	cytoplasmic microtubule organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of structures formed of microtubules and associated proteins in the cytoplasm of a cell.	tmpzr1t_l9r_go_relaxed.owl	cytoplasmic microtubule organisation|cytoplasmic microtubule organization and biogenesis													biological_process											owl:Class	
GO:0097435	biolink:NamedThing	supramolecular fiber organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a supramolecular fiber, a polymer consisting of an indefinite number of protein or protein complex subunits that have polymerised to form a fiber-shaped structure.	tmpzr1t_l9r_go_relaxed.owl	extracellular fibril organisation|fibril organization|extracellular fibril organization|extracellular fibril organization and biogenesis|fibril organisation							pr	2012-11-27T15:46:25Z			GO:0043206		biological_process											owl:Class	
GO:0097346	biolink:NamedThing	INO80-type complex	A chromatin remodeling protein complex initially purified from S. cerevisiae and containing more than 10 subunits, including the SWR1-related complexes. INO80 (inositol requiring 80)-type complexes have diverse functions, including promoting transcriptional activation and DNA repair.	tmpzr1t_l9r_go_relaxed.owl								pr	2012-06-20T11:26:55Z					cellular_component											owl:Class	
GO:1903565	biolink:NamedThing	negative regulation of protein localization to cilium	Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cilium.	tmpzr1t_l9r_go_relaxed.owl	down regulation of protein localization to cilium|downregulation of protein localization to cilium|down-regulation of protein localization to cilium|inhibition of protein localization to cilium							krc	2014-10-24T20:58:20Z					biological_process											owl:Class	
GO:1903828	biolink:NamedThing	negative regulation of protein localization	Any process that stops, prevents or reduces the frequency, rate or extent of a protein localization.	tmpzr1t_l9r_go_relaxed.owl	downregulation of cellular protein localization|inhibition of cellular protein localisation|down regulation of cellular protein localisation|down-regulation of cellular protein localization|inhibition of cellular protein localization|negative regulation of cellular protein localisation|downregulation of cellular protein localisation|negative regulation of cellular protein localization|down regulation of cellular protein localization|down-regulation of cellular protein localisation	https://github.com/geneontology/go-ontology/issues/22021						jl	2015-01-20T14:32:24Z					biological_process											owl:Class	
GO:0006863	biolink:NamedThing	purine nucleobase transport	The directed movement of purine bases, one of the two classes of nitrogen-containing ring compounds found in DNA and RNA, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	purine base transport|purine transmembrane transport|purine base transmembrane transport|purine transport											GO:0015852		biological_process											owl:Class	
GO:2000944	biolink:NamedThing	positive regulation of amylopectin metabolic process	Any process that activates or increases the frequency, rate or extent of amylopectin metabolic process.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of Amylopectin metabolism							tt	2011-08-01T02:10:36Z					biological_process											owl:Class	
GO:0071083	biolink:NamedThing	alphaV-beta3 integrin-CD47-FCER2 complex	A protein complex that consists of an alphaV-beta3 integrin complex bound to the cell surface protein CD47 and the low-affinity immunoglobulin epsilon Fc receptor (FCER2).	tmpzr1t_l9r_go_relaxed.owl	ITGAV-ITGB3-CD447-FCER2 complex							mah	2009-11-06T04:44:20Z					cellular_component											owl:Class	
GO:0106103	biolink:NamedThing	COPII vesicles tethering complex	A protein complex that resides in the cis-golgi membrane and plays a role in the tethering of COPII vesicles, through an interaction with vesicle tethering proteins (p115 in H. Sapiens and Uso1 S. cerevisiae), granting the cis-Golgi and endoplasmic reticulum to Golgi vesicle-mediated transport. It is composed by GRASP65 and GM130 protein in H. sapiens and by Bug1 and Grh1 proteins in S. cerevisiae.	tmpzr1t_l9r_go_relaxed.owl	GRASP65-GM130 complex|Bug1-Grh1 complex							hjd	2018-02-15T23:36:12Z					cellular_component											owl:Class	
GO:0060169	biolink:NamedThing	negative regulation of adenosine receptor signaling pathway	Any process that stops, prevents, or reduces the frequency, rate or extent of the adenosine receptor signaling pathway. The adenosine receptor pathway is the series of molecular signals generated as a consequence of an adenosine receptor binding to one of its physiological ligands.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of adenosine receptor signalling pathway													biological_process											owl:Class	
GO:0018985	biolink:NamedThing	pronuclear envelope synthesis	Synthesis and ordering of the envelope of pronuclei.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1990487	biolink:NamedThing	anaerobic lignin catabolic process	The chemical reactions and pathways resulting in the breakdown of lignin in the absence of oxygen. Lignin is a class of polymers of phenylpropanoid units.	tmpzr1t_l9r_go_relaxed.owl	anaerobic lignin degradation							tt	2014-09-20T17:35:09Z					biological_process											owl:Class	
GO:0046274	biolink:NamedThing	lignin catabolic process	The chemical reactions and pathways resulting in the breakdown of lignins, a class of polymers of phenylpropanoid units.	tmpzr1t_l9r_go_relaxed.owl	lignin degradation|lignin catabolism|lignin breakdown													biological_process											owl:Class	
GO:0001786	biolink:NamedThing	phosphatidylserine binding	Binding to phosphatidylserine, a class of glycophospholipids in which a phosphatidyl group is esterified to the hydroxyl group of L-serine.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0008989	biolink:NamedThing	rRNA (guanine-N1-)-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing N1-methylguanine.	tmpzr1t_l9r_go_relaxed.owl	ribosomal ribonucleate guanine 1-methyltransferase activity|S-adenosyl-L-methionine:rRNA (guanine-1-N-)-methyltransferase activity|S-adenosyl-L-methionine:rRNA (guanine-N1-)-methyltransferase activity				MetaCyc:RRNA-GUANINE-N1--METHYLTRANSFERASE-RXN									molecular_function											owl:Class	
GO:1990441	biolink:NamedThing	negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress	Any process that stops, prevents, or reduces the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of an endoplasmic reticulum stress.	tmpzr1t_l9r_go_relaxed.owl	inhibition of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress|down regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress|down-regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress|suppression of transcription from RNA polymerase II promoter under ER stress|repression of transcription from RNA polymerase II promoter under ER stress|reduction of transcription from RNA polymerase II promoter under ER stress|ER stress-induced negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter in response to ER stress							bf	2014-07-31T13:08:54Z					biological_process											owl:Class	
GO:0050455	biolink:NamedThing	columbamine oxidase activity	Catalysis of the reaction: 2 columbamine + O(2) = 2 berberine + 2 H(2)O.	tmpzr1t_l9r_go_relaxed.owl	columbamine:oxygen oxidoreductase (cyclizing)|berberine synthase activity				RHEA:23564|MetaCyc:COLUMBAMINE-OXIDASE-RXN|EC:1.21.3.2|KEGG_REACTION:R00044									molecular_function											owl:Class	
GO:0043792	biolink:NamedThing	enamidase activity	Catalysis of the reaction: 1,4,5,6-tetrahydro-6-oxonicotinate + 2 H(2)O = 2-formylglutarate + NH(4)(+).	tmpzr1t_l9r_go_relaxed.owl	6-oxo-1,4,5,6-tetrahydronicotinate amidohydrolase activity				EC:3.5.2.18|RHEA:17209|MetaCyc:3.5.2.18-RXN|KEGG_REACTION:R07984									molecular_function											owl:Class	
GO:1900343	biolink:NamedThing	negative regulation of methane biosynthetic process from dimethyl sulfide	Any process that stops, prevents or reduces the frequency, rate or extent of methane biosynthetic process from dimethyl sulfide.	tmpzr1t_l9r_go_relaxed.owl	downregulation of methane biosynthetic process from dimethyl sulfide|down regulation of methane biosynthetic process from dimethyl sulfide|down-regulation of methane biosynthetic process from dimethyl sulfide|inhibition of methane biosynthetic process from dimethyl sulfide							tt	2012-04-06T02:06:47Z					biological_process											owl:Class	
GO:1900342	biolink:NamedThing	regulation of methane biosynthetic process from dimethyl sulfide	Any process that modulates the frequency, rate or extent of methane biosynthetic process from dimethyl sulfide.	tmpzr1t_l9r_go_relaxed.owl								tt	2012-04-06T02:06:38Z					biological_process											owl:Class	
GO:0051621	biolink:NamedThing	regulation of norepinephrine uptake	Any process that modulates the frequency, rate or extent of the directed movement of the neurotransmitter norepinephrine into a cell.	tmpzr1t_l9r_go_relaxed.owl	regulation of norepinephrine import|regulation of noradrenaline uptake|regulation of levarterenol uptake													biological_process											owl:Class	
GO:1904760	biolink:NamedThing	regulation of myofibroblast differentiation	Any process that modulates the frequency, rate or extent of myofibroblast differentiation.	tmpzr1t_l9r_go_relaxed.owl	regulation of myofibroblast cell differentiation							rph	2015-10-23T12:15:05Z					biological_process											owl:Class	
GO:0008506	biolink:NamedThing	sucrose:proton symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sucrose(out) + H+(out) = sucrose(in) + H+(in).	tmpzr1t_l9r_go_relaxed.owl	sucrose:hydrogen symporter activity|hydrogen/sucrose transporter activity													molecular_function											owl:Class	
GO:1905064	biolink:NamedThing	negative regulation of vascular associated smooth muscle cell differentiation	Any process that stops, prevents or reduces the frequency, rate or extent of vascular smooth muscle cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of vascular smooth muscle cell differentiation|inhibition of VSMC differentiation|down-regulation of vascular associated smooth muscle cell differentiation|down regulation of VSMC differentiation|negative regulation of VSMC differentiation|inhibition of vascular associated smooth muscle cell differentiation|down regulation of vascular smooth muscle cell differentiation|down-regulation of VSMC differentiation|negative regulation of vascular smooth muscle cell differentiation|inhibition of vascular smooth muscle cell differentiation|down regulation of vascular associated smooth muscle cell differentiation|downregulation of vascular associated smooth muscle cell differentiation|downregulation of VSMC differentiation|downregulation of vascular smooth muscle cell differentiation							rph	2016-03-21T11:15:03Z					biological_process											owl:Class	
GO:1902738	biolink:NamedThing	regulation of chondrocyte differentiation involved in endochondral bone morphogenesis	Any process that modulates the rate, frequency, or extent of the process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte that will contribute to the development of a bone. A chondrocyte is a polymorphic cell that forms cartilage.	tmpzr1t_l9r_go_relaxed.owl								mr	2014-02-26T15:36:15Z					biological_process											owl:Class	
GO:0062225	biolink:NamedThing	negative regulation of somatic muscle development	Any process that decreases the rate, frequency or extent of somatic muscle development.	tmpzr1t_l9r_go_relaxed.owl								dph	2020-03-13T19:06:27Z					biological_process											owl:Class	
GO:0018966	biolink:NamedThing	styrene metabolic process	The chemical reactions and pathways involving styrene, an aromatic hydrocarbon liquid soluble in ether and alcohol. When heated, exposed to light or added to a peroxide catalyst, it undergoes polymerization to form polystyrene, a versatile material used in the manufacture of plastics, synthetic rubber, thermal insulation, and packaging. Styrene is a classified mutagen and a suspected carcinogen.	tmpzr1t_l9r_go_relaxed.owl	styrene metabolism				UM-BBD_pathwayID:sty									biological_process											owl:Class	
GO:0021840	biolink:NamedThing	directional guidance of interneurons involved in migration from the subpallium to the cortex	The creation and reception of signals that control the direction of migration of interneurons as a component of the process of migration from the subpallium to the cortex.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0060436	biolink:NamedThing	bronchiole morphogenesis	The process in which a bronchiole is generated and organized. A bronchiole is the first airway branch that no longer contains cartilage; it is a branch of the bronchi.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0046941	biolink:NamedThing	azetidine-2-carboxylic acid acetyltransferase activity	Catalysis of the reaction: L-azetidine-2-carboxylic acid + acetyl-CoA = CoA-SH + N-acetyl azetidine-2-carboxylic acid.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0010343	biolink:NamedThing	singlet oxygen-mediated programmed cell death	Programmed cell death induced by singlet oxygen. Programmed cell death is the cell death resulting from activation of endogenous cellular processes.	tmpzr1t_l9r_go_relaxed.owl	light-dependent programmed cell death|programmed cell death in response to singlet oxygen													biological_process											owl:Class	
GO:0072012	biolink:NamedThing	glomerulus vasculature development	The biological process whose specific outcome is the progression of a glomerulus vasculature from an initial condition to its mature state. This process begins with the formation of the glomerulus vasculature and ends with the mature structure. The glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the glomerulus.	tmpzr1t_l9r_go_relaxed.owl	glomerulus capillary development							mah	2010-01-25T02:05:04Z					biological_process											owl:Class	
GO:0070503	biolink:NamedThing	selenium-containing prosthetic group metabolic process	The chemical reactions and pathways involving a prosthetic group that contains selenium, as in the selenium-dependent molybdenum hydroxylases. The selenium atom in the prosthetic group is required for enzymatic function but is labile to a variety of treatments.	tmpzr1t_l9r_go_relaxed.owl	selenium-containing prosthetic group metabolism													biological_process											owl:Class	
GO:0010088	biolink:NamedThing	phloem development	The formation of the principal food-conducting tissue of a vascular plant.	tmpzr1t_l9r_go_relaxed.owl	phloem histogenesis													biological_process											owl:Class	
GO:0044525	biolink:NamedThing	peptidyl-cystine sulfhydration	The modification of a peptidyl-cystine residue in a protein by the addition of sulfur, to form peptidyl-cysteine persulfide.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-03-15T09:44:07Z					biological_process											owl:Class	
GO:1903940	biolink:NamedThing	negative regulation of TORC2 signaling	Any process that stops, prevents or reduces the frequency, rate or extent of TORC2 signaling.	tmpzr1t_l9r_go_relaxed.owl	downregulation of TORC2 signal transduction|down regulation of TORC2 signaling|negative regulation of TORC2 signal transduction|inhibition of TORC2 signaling|downregulation of TORC2 signaling|down-regulation of TORC2 signaling|down regulation of TORC2 signal transduction|inhibition of TORC2 signal transduction|down-regulation of TORC2 signal transduction							al	2015-02-16T18:28:50Z					biological_process											owl:Class	
GO:1990553	biolink:NamedThing	mitochondrial 5'-adenylyl sulfate transmembrane transport	The process in which 5'-adenylyl sulfate is transported across a mitochondrial membrane, into or out of the mitochondrion.	tmpzr1t_l9r_go_relaxed.owl								vw	2014-11-19T12:32:01Z					biological_process											owl:Class	
GO:0061881	biolink:NamedThing	positive regulation of anterograde axonal transport of mitochondrion	Any process that activates or increasesthe frequency, rate or extent of the directed movement of mitochondria along microtubules in axons away from the cell body and towards the presynapse.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of anterograde axon transport of mitochondria							dph	2017-05-30T14:21:08Z					biological_process											owl:Class	
GO:0031361	biolink:NamedThing	integral component of thylakoid membrane	The component of the thylakoid membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.	tmpzr1t_l9r_go_relaxed.owl	integral to thylakoid membrane													cellular_component											owl:Class	
GO:0046608	biolink:NamedThing	carotenoid isomerase activity	Catalysis of the isomerization of poly-cis-carotenoids to all-trans-carotenoids.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0032024	biolink:NamedThing	positive regulation of insulin secretion	Any process that activates or increases the frequency, rate or extent of the regulated release of insulin.	tmpzr1t_l9r_go_relaxed.owl	activation of insulin secretion|upregulation of insulin secretion|stimulation of insulin secretion|up regulation of insulin secretion|up-regulation of insulin secretion													biological_process											owl:Class	
GO:0075229	biolink:NamedThing	negative regulation of encysted zoospore germination	Any process that stops, prevents, or reduces the frequency, rate or extent of encysted zoospore germination.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of encysted zoospore germination on or near host													biological_process											owl:Class	
GO:1904057	biolink:NamedThing	negative regulation of sensory perception of pain	Any process that stops, prevents or reduces the frequency, rate or extent of sensory perception of pain.	tmpzr1t_l9r_go_relaxed.owl	down regulation of perception of physiological pain|negative regulation of nociception|inhibition of sensory perception of pain|downregulation of nociception|down regulation of nociception|down-regulation of sensory perception of pain|negative regulation of perception of physiological pain|downregulation of sensory perception of pain|inhibition of nociception|down regulation of sensory perception of pain|down-regulation of nociception|down-regulation of perception of physiological pain|inhibition of perception of physiological pain|downregulation of perception of physiological pain							sl	2015-03-18T20:33:57Z					biological_process											owl:Class	
GO:1905231	biolink:NamedThing	cellular response to borneol	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a borneol stimulus.	tmpzr1t_l9r_go_relaxed.owl								sl	2016-06-07T17:18:44Z					biological_process											owl:Class	
GO:1905230	biolink:NamedThing	response to borneol	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a borneol stimulus.	tmpzr1t_l9r_go_relaxed.owl								sl	2016-06-07T17:18:36Z					biological_process											owl:Class	
GO:0015760	biolink:NamedThing	glucose-6-phosphate transport	The directed movement of glucose-6-phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Glucose-6-phosphate is a monophosphorylated derivative of glucose with the phosphate group attached to C-6.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0044805	biolink:NamedThing	late nucleophagy	A type of nucleophagy, distinct from piecemeal microautophagy of the nucleus (PNM) where the nuclear material is delivered to the vacuole/lysosome for breakdown and recycling later than observed for PNM.	tmpzr1t_l9r_go_relaxed.owl	LN							jl	2013-09-10T15:58:23Z					biological_process											owl:Class	
GO:0044804	biolink:NamedThing	autophagy of nucleus	A form of autophagy, by which damaged or non-essential parts of the nucleus, or even an entire nucleus is degraded.	tmpzr1t_l9r_go_relaxed.owl	nucleus degradation|nucleophagy							jl	2013-09-10T15:50:25Z					biological_process											owl:Class	
GO:1903502	biolink:NamedThing	translation repressor complex	A protein complex which is capable of translation repressor activity.	tmpzr1t_l9r_go_relaxed.owl						An example of this is Eif4e in drome (P48598) in PMID:14723848 (inferred from physical interaction).		bhm	2014-09-30T12:44:27Z					cellular_component											owl:Class	
GO:0031086	biolink:NamedThing	nuclear-transcribed mRNA catabolic process, deadenylation-independent decay	A pathway of degradation of nuclear-transcribed mRNAs that proceeds through a series of steps that is independent of deadenylation, but requires decapping followed by transcript decay, and that can regulate mRNA stability.	tmpzr1t_l9r_go_relaxed.owl	mRNA catabolism, deadenylation-independent decay|deadenylylation-independent mRNA decay|mRNA catabolism, deadenylation-independent|mRNA catabolism, deadenylylation-independent|mRNA degradation, deadenylation-independent decay|mRNA breakdown, deadenylation-independent decay|mRNA catabolic process, deadenylylation-independent|mRNA catabolic process, deadenylation-independent|deadenylation-independent mRNA decay|nuclear mRNA catabolic process, deadenylation-independent decay													biological_process											owl:Class	
GO:0000956	biolink:NamedThing	nuclear-transcribed mRNA catabolic process	The chemical reactions and pathways resulting in the breakdown of nuclear-transcribed mRNAs in eukaryotic cells.	tmpzr1t_l9r_go_relaxed.owl	nuclear mRNA degradation|nuclear mRNA catabolism|nuclear mRNA breakdown													biological_process											owl:Class	
GO:1903675	biolink:NamedThing	negative regulation of cap-dependent translational initiation	Any process that stops, prevents or reduces the frequency, rate or extent of cap-dependent translational initiation.	tmpzr1t_l9r_go_relaxed.owl	down regulation of cap-dependent translational initiation|down-regulation of cap-dependent translational initiation|downregulation of cap-dependent translational initiation|inhibition of cap-dependent translational initiation							bf	2014-11-27T19:50:31Z					biological_process											owl:Class	
GO:0009144	biolink:NamedThing	purine nucleoside triphosphate metabolic process	The chemical reactions and pathways involving purine nucleoside triphosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with triphosphate on the sugar.	tmpzr1t_l9r_go_relaxed.owl	purine nucleoside triphosphate metabolism													biological_process											owl:Class	
GO:0106028	biolink:NamedThing	neuron projection retraction	The organization process which results in the disassembly (either partial or complete) of constituent parts of a neuron projection. A neuron projection is a prolongation or process extending from a nerve cell, e.g. an axon or dendrite.	tmpzr1t_l9r_go_relaxed.owl	neuron projection disassembly							hjd	2017-06-23T18:32:42Z					biological_process											owl:Class	
GO:0106027	biolink:NamedThing	neuron projection organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a prolongation or process extending from a neuron, e.g. an axon, or a dendrite.	tmpzr1t_l9r_go_relaxed.owl								hjd	2017-06-23T18:30:18Z					biological_process											owl:Class	
GO:0032450	biolink:NamedThing	maltose alpha-glucosidase activity	Catalysis of the reaction: alpha-maltose + H2O = 2 alpha-D-glucose.	tmpzr1t_l9r_go_relaxed.owl	maltase activity				MetaCyc:RXN-2141|EC:3.2.1.20									molecular_function											owl:Class	
GO:0004558	biolink:NamedThing	alpha-1,4-glucosidase activity	Catalysis of the hydrolysis of terminal, non-reducing alpha-(1->4)-linked alpha-D-glucose residues with release of alpha-D-glucose.	tmpzr1t_l9r_go_relaxed.owl	lysosomal alpha-glucosidase activity|glucosidosucrase activity|alpha-glucopyranosidase activity|alpha-D-glucosidase activity|glucoinvertase activity|alpha-glucosidase II|glucosidoinvertase activity|maltase-glucoamylase activity|alpha-glucoside hydrolase activity|acid maltase activity|alpha-D-glucoside glucohydrolase activity				Reactome:R-HSA-189053|Reactome:R-HSA-5659899|Reactome:R-HSA-5659879|Reactome:R-HSA-191101|EC:3.2.1.20|MetaCyc:MALTODEXGLUCOSID-RXN|Reactome:R-HSA-5659861|Reactome:R-HSA-191116|Reactome:R-HSA-189102|Reactome:R-HSA-5659922|Reactome:R-HSA-191108							GO:0016982|GO:0004562		molecular_function											owl:Class	
GO:0047707	biolink:NamedThing	biotin-CoA ligase activity	Catalysis of the reaction: ATP + biotin + CoA = AMP + diphosphate + biotinyl-CoA.	tmpzr1t_l9r_go_relaxed.owl	biotinyl-CoA synthetase activity|biotin:CoA ligase (AMP-forming)|biotin CoA synthetase activity|biotinyl coenzyme A synthetase activity				MetaCyc:BIOTIN--COA-LIGASE-RXN|EC:6.2.1.11|RHEA:19681									molecular_function											owl:Class	
GO:0043878	biolink:NamedThing	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity	Catalysis of the reaction: D-glyceraldehyde 3-phosphate + NAD+ + H2O = 3-phospho-D-glycerate + NADH + H+.	tmpzr1t_l9r_go_relaxed.owl	NAD+-dependent glyceraldehyde-3-phosphate dehydrogenase activity|glyceraldehyde-3-phosphate dehydrogenase (NAD) activity|non-phosphorylating glyceraldehyde-3-phosphate dehydrogenase (NAD)|glyceraldehyde-3-phosphate dehydrogenase (NAD) (non-phosphorylating) activity				RHEA:25294|EC:1.2.1.3|MetaCyc:RXN-3443									molecular_function											owl:Class	
GO:0070164	biolink:NamedThing	negative regulation of adiponectin secretion	Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of adiponectin from a cell.	tmpzr1t_l9r_go_relaxed.owl	inhibition of adiponectin secretion|down-regulation of adiponectin secretion|down regulation of adiponectin secretion|downregulation of adiponectin secretion													biological_process											owl:Class	
GO:0051046	biolink:NamedThing	regulation of secretion	Any process that modulates the frequency, rate or extent of the controlled release of a substance from a cell or a tissue.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1900842	biolink:NamedThing	positive regulation of helvolic acid biosynthetic process	Any process that activates or increases the frequency, rate or extent of helvolic acid biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	upregulation of helvolic acid biosynthetic process|up-regulation of helvolic acid biosynthetic process|up regulation of helvolic acid biosynthetic process							di	2012-06-07T09:39:05Z					biological_process											owl:Class	
GO:0033289	biolink:NamedThing	intraconoid microtubule	A microtubule located such that it threads through the conoid and projects through the polar ring.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0048046	biolink:NamedThing	apoplast	The cell membranes and intracellular regions in a plant are connected through plasmodesmata, and plants may be described as having two major compartments: the living symplast and the non-living apoplast. The apoplast is external to the plasma membrane and includes cell walls, intercellular spaces and the lumen of dead structures such as xylem vessels. Water and solutes pass freely through it.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Apoplast									cellular_component											owl:Class	
GO:1904703	biolink:NamedThing	negative regulation of protein localization to adherens junction	Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to adherens junction. An adherens junction is a cell-cell junction composed of the epithelial cadherin-catenin complex at which the cytoplasmic face of the plasma membrane is attached to actin filaments.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of protein localisation in cell-cell adherens junction|down-regulation of protein localisation in cell-cell adherens junction|down regulation of protein localization to cell-cell adherens junction|downregulation of protein localisation in cell-cell adherens junction|inhibition of protein localisation to cell-cell adherens junction|downregulation of protein localization in cell-cell adherens junction|downregulation of protein localisation to cell-cell adherens junction|down regulation of protein localisation in cell-cell adherens junction|inhibition of protein localization to cell-cell adherens junction|negative regulation of protein localisation to cell-cell adherens junction|inhibition of protein localisation in cell-cell adherens junction|negative regulation of protein localization in cell-cell adherens junction|downregulation of protein localization to cell-cell adherens junction|down-regulation of protein localization in cell-cell adherens junction|down-regulation of protein localization to cell-cell adherens junction|down-regulation of protein localisation to cell-cell adherens junction|inhibition of protein localization in cell-cell adherens junction|down regulation of protein localization in cell-cell adherens junction|down regulation of protein localisation to cell-cell adherens junction							kmv	2015-10-01T15:11:56Z					biological_process											owl:Class	
GO:0150119	biolink:NamedThing	negative regulation of protein localization to cell-cell junction	Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cell-cell junction.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of protein localisation to cell-cell junction							bc	2019-11-21T13:53:34Z					biological_process											owl:Class	
GO:1901828	biolink:NamedThing	zeaxanthin bis(beta-D-glucoside) metabolic process	The chemical reactions and pathways involving zeaxanthin bis(beta-D-glucoside).	tmpzr1t_l9r_go_relaxed.owl	zeaxanthin diglucoside metabolism|zeaxanthin bis(beta-D-glucoside) metabolism							yaf	2013-01-22T12:31:56Z					biological_process											owl:Class	
GO:0050052	biolink:NamedThing	leukotriene-E4 20-monooxygenase activity	Catalysis of the reaction: H(+) + leukotriene E(4) + NADPH + O(2) = 20-hydroxy-leukotriene E(4) + H(2)O + NADP(+).	tmpzr1t_l9r_go_relaxed.owl	leukotriene-E4 w-hydroxylase activity|leukotriene-E(4) omega-hydroxylase activity|leukotriene-E4 omega-hydroxylase activity|(7E,9E,11Z,14Z)-(5S,6R)-6-(cystein-S-yl)-5-hydroxyicosa-7,9,11,14-tetraenoate,NADPH:oxygen oxidoreductase (20-hydroxylating)				RHEA:24120|KEGG_REACTION:R04256|MetaCyc:LEUKOTRIENE-E4-20-MONOOXYGENASE-RXN|EC:1.14.13.34									molecular_function											owl:Class	
GO:0033330	biolink:NamedThing	kaempferol O-glucoside biosynthetic process	The chemical reactions and pathways leading to the formation of O-glucosylated derivatives of kaempferol.	tmpzr1t_l9r_go_relaxed.owl	kaempferol O-glucoside biosynthesis|kaempferol O-glucoside synthesit|kaempferol O-glucoside anabolism|kaempferol O-glucoside formation				MetaCyc:PWY-5320									biological_process											owl:Class	
GO:0070346	biolink:NamedThing	positive regulation of fat cell proliferation	Any process that activates or increases the rate or extent of fat cell proliferation.	tmpzr1t_l9r_go_relaxed.owl	up regulation of fat cell proliferation|stimulation of fat cell proliferation|positive regulation of adipocyte proliferation|activation of fat cell proliferation|upregulation of fat cell proliferation|up-regulation of fat cell proliferation|positive regulation of adipose cell proliferation													biological_process											owl:Class	
GO:1905960	biolink:NamedThing	response to differentiation-inducing factor 2	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)pentan-1-one stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)pentan-1-one|response to DIF2|response to DIF-2							tb	2017-02-22T18:45:40Z					biological_process											owl:Class	
GO:0002295	biolink:NamedThing	T-helper cell lineage commitment	The process in which a CD4-positive, alpha-beta T cell becomes committed to becoming a T-helper cell, a CD4-positive, alpha-beta T cell specialized to promote various immunological processes.	tmpzr1t_l9r_go_relaxed.owl	Thp lineage commitment|Th0 lineage commitment|T-helper cell fate commitment													biological_process											owl:Class	
GO:0002456	biolink:NamedThing	T cell mediated immunity	Any process involved in the carrying out of an immune response by a T cell.	tmpzr1t_l9r_go_relaxed.owl	T lymphocyte mediated immunity|cellular immune response|T-lymphocyte mediated immunity|T-cell mediated immunity|cell-mediated immunity													biological_process											owl:Class	
GO:0042214	biolink:NamedThing	terpene metabolic process	The chemical reactions and pathways involving terpenes, any of a large group of hydrocarbons that are made up of isoprene (C5H8) units which may be cyclic, acyclic or multicyclic, saturated or unsaturated, and may contain various functional groups.	tmpzr1t_l9r_go_relaxed.owl	terpene metabolism													biological_process											owl:Class	
GO:1990001	biolink:NamedThing	inhibition of cysteine-type endopeptidase activity involved in apoptotic process	Any process that prevents the activation of an inactive cysteine-type endopeptidase involved in an apoptotic process.	tmpzr1t_l9r_go_relaxed.owl								pr	2012-12-05T15:42:50Z					biological_process											owl:Class	
GO:0043154	biolink:NamedThing	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process	Any process that stops, prevents, or reduces the frequency, rate or extent of a cysteine-type endopeptidase activity involved in the apoptotic process.	tmpzr1t_l9r_go_relaxed.owl	down regulation of caspase activity|negative regulation of caspase activation|inhibition of caspase activation|inhibition of caspase activity|down-regulation of caspase activity|downregulation of caspase activity|negative regulation of caspase activity											GO:0001719		biological_process											owl:Class	
GO:0008405	biolink:NamedThing	arachidonic acid 11,12-epoxygenase activity	Catalysis of an NADPH- and oxygen-dependent reaction that converts arachidonic acid to cis-11,12-epoxyeicosatrienoic acid.	tmpzr1t_l9r_go_relaxed.owl	cytochrome P450 CYP2C38				RHEA:51480									molecular_function											owl:Class	
GO:0003405	biolink:NamedThing	optic vesicle elongation	The developmental growth that results in the lengthening of the optic vesicle in the posterior direction.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-12-21T01:59:50Z					biological_process											owl:Class	
GO:0030207	biolink:NamedThing	chondroitin sulfate catabolic process	The chemical reactions and pathways resulting in the breakdown of chondroitin sulfate, any member of a group of 10-60 kDa glycosaminoglycans, widely distributed in cartilage and other mammalian connective tissues, the repeat units of which consist of beta-(1,4)-linked D-glucuronyl beta-(1,3)-N-acetyl-D-galactosamine sulfate.	tmpzr1t_l9r_go_relaxed.owl	chondroitin sulphate catabolic process|chondroitin sulfate catabolism|chondroitin sulfate degradation|chondroitin sulfate breakdown|chondroitin sulphate catabolism													biological_process											owl:Class	
GO:0015090	biolink:NamedThing	low-affinity ferric iron ion transmembrane transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Fe2+(out) = Fe2+(in). In low-affinity transport the transporter is able to bind the solute only if it is present at very high concentrations.	tmpzr1t_l9r_go_relaxed.owl	low affinity iron ion transmembrane transporter activity|low affinity iron transporter activity													molecular_function											owl:Class	
GO:0015091	biolink:NamedThing	ferric iron transmembrane transporter activity	Enables the transfer of ferric iron (Fe(III) or Fe3+) ions from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl						Ferric iron is rarely transported in the free form. Some bacteria have a system in which an outer membrane protein takes iron away from host ferritin or lactoferrin and transport it to a Fe3+ binding protein in the periplasm. The periplasmic protein then delivers the Fe3+ to a transport system located in the cytoplasmic membrane. Consider also GO:0015343 siderophore transmembrane transporter activity.								molecular_function											owl:Class	
GO:0018418	biolink:NamedThing	nickel incorporation into iron-sulfur cluster via tris-L-cysteinyl L-cysteine persulfido L-glutamato L-histidino L-serinyl nickel triiron disulfide trioxide	The incorporation of nickel into a 3Fe-2S complex by tris-L-cysteinyl L-cysteine persulfido L-glutamato L-histidino L-serinyl nickel triiron disulfide trioxide.	tmpzr1t_l9r_go_relaxed.owl	nickel incorporation into iron-sulphur cluster via tris-L-cysteinyl L-cysteine persulphido L-glutamato L-histidino L-serinyl nickel triiron disulphide trioxide				RESID:AA0									biological_process											owl:Class	
GO:0019359	biolink:NamedThing	nicotinamide nucleotide biosynthetic process	The chemical reactions and pathways resulting in the formation of nicotinamide nucleotides, any nucleotide that contains combined nicotinamide.	tmpzr1t_l9r_go_relaxed.owl	nicotinamide nucleotide formation|nicotinamide nucleotide synthesis|nicotinamide nucleotide biosynthesis|nicotinamide nucleotide anabolism													biological_process											owl:Class	
GO:0019363	biolink:NamedThing	pyridine nucleotide biosynthetic process	The chemical reactions and pathways resulting in the formation of a pyridine nucleotide, a nucleotide characterized by a pyridine derivative as a nitrogen base.	tmpzr1t_l9r_go_relaxed.owl	pyridine nucleotide synthesis|pyridine nucleotide formation|pyridine nucleotide biosynthesis|pyridine nucleotide anabolism				MetaCyc:PYRIDNUCSYN-PWY									biological_process											owl:Class	
GO:0031907	biolink:NamedThing	microbody lumen	The volume enclosed by the membranes of a microbody.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0055109	biolink:NamedThing	invagination involved in gastrulation with mouth forming second	The infolding of the epithelial sheet into the embryo involved in deuterostomic gastrulation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0030061	biolink:NamedThing	mitochondrial crista	Any of the inward folds of the mitochondrial inner membrane. Their number, extent, and shape differ in mitochondria from different tissues and organisms. They appear to be devices for increasing the surface area of the mitochondrial inner membrane, where the enzymes of electron transport and oxidative phosphorylation are found. Their shape can vary with the respiratory state of the mitochondria.	tmpzr1t_l9r_go_relaxed.owl	cristae|mitochondrial cristae				NIF_Subcellular:sao333328131	See also the cellular component term 'mitochondrial inner membrane ; GO:0005743'.								cellular_component											owl:Class	
GO:0070920	biolink:NamedThing	regulation of production of small RNA involved in gene silencing by RNA	Any process that modulates the frequency, rate or extent of the production of small RNA involved in gene silencing by RNA.	tmpzr1t_l9r_go_relaxed.owl	regulation of gene silencing by RNA, production of guide RNA|regulation of gene silencing by RNA, production of small RNA							mah	2009-09-11T03:41:59Z					biological_process											owl:Class	
GO:0071296	biolink:NamedThing	cellular response to biotin	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biotin stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to vitamin B7|cellular response to Bios IIB|cellular response to vitamin H|cellular response to coenzyme R							mah	2009-12-10T04:28:22Z					biological_process											owl:Class	
GO:1904957	biolink:NamedThing	negative regulation of midbrain dopaminergic neuron differentiation	Any process that stops, prevents or reduces the frequency, rate or extent of midbrain dopaminergic neuron differentiation.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of mDA neuron differentiation|inhibition of midbrain dopaminergic neuron production|down-regulation of midbrain dopaminergic neuron production|down regulation of midbrain dopaminergic neuron differentiation|down-regulation of midbrain DA neurogenesis|down-regulation of midbrain dopaminergic neuron differentiation|downregulation of midbrain dopaminergic neuron differentiation|negative regulation of midbrain dopaminergic neuron production|downregulation of DA neurogenesis from midbrain floor plate|down regulation of DA neurogenesis from midbrain floor plate|down regulation of mDA neuron differentiation|downregulation of midbrain dopaminergic neuron production|inhibition of mDA neuron differentiation|inhibition of midbrain dopaminergic neuron differentiation|negative regulation of midbrain DA neurogenesis|down-regulation of DA neurogenesis from midbrain floor plate|downregulation of mDA neuron differentiation|negative regulation of mDA neuron differentiation|down regulation of midbrain dopaminergic neuron production|downregulation of midbrain DA neurogenesis|inhibition of midbrain DA neurogenesis|inhibition of DA neurogenesis from midbrain floor plate|negative regulation of DA neurogenesis from midbrain floor plate|down regulation of midbrain DA neurogenesis							bf	2016-02-09T12:00:29Z					biological_process											owl:Class	
GO:1904339	biolink:NamedThing	negative regulation of dopaminergic neuron differentiation	Any process that stops, prevents or reduces the frequency, rate or extent of dopaminergic neuron differentiation.	tmpzr1t_l9r_go_relaxed.owl	downregulation of dopaminergic neuron differentiation|down regulation of dopaminergic neuron differentiation|inhibition of dopaminergic neuron differentiation|down-regulation of dopaminergic neuron differentiation							sl	2015-06-11T18:06:25Z					biological_process											owl:Class	
GO:0033067	biolink:NamedThing	macrolide metabolic process	The chemical reactions and pathways involving macrolides, any of a large group of polyketide compounds that contain a large lactone ring with few or no double bonds and no nitrogen atoms, linked glycosidically to one or more sugar groups. The macrolides include the carbomycins, the erythromycins, oleandomycin, oligomycins, and the spiramycins, and act as antibiotics, mainly against Gram-positive bacteria.	tmpzr1t_l9r_go_relaxed.owl	macrolide metabolism													biological_process											owl:Class	
GO:0035510	biolink:NamedThing	DNA dealkylation	The removal of an alkyl group from one or more nucleotides within an DNA molecule.	tmpzr1t_l9r_go_relaxed.owl								bf	2010-04-30T02:20:08Z					biological_process											owl:Class	
GO:0061391	biolink:NamedThing	negative regulation of direction of cell growth	Any process that decreases the direction of cell growth.	tmpzr1t_l9r_go_relaxed.owl								dph	2011-07-14T10:25:55Z					biological_process											owl:Class	
GO:0043861	biolink:NamedThing	agmatine:putrescine antiporter activity	Catalysis of the reaction: agmatine(out) + putrescine(in) = agmatine(in) + putrescine(out).	tmpzr1t_l9r_go_relaxed.owl	agmatine-putrescine antiporter activity|agmatine/putrescine antiporter activity													molecular_function											owl:Class	
GO:0047510	biolink:NamedThing	(S)-2-methylmalate dehydratase activity	Catalysis of the reaction: S-citramalate = H(2)O + mesaconate.	tmpzr1t_l9r_go_relaxed.owl	(+)-citramalic hydro-lyase activity|mesaconase activity|(+)-citramalate hydro-lyase activity|(S)-2-methylmalate hydro-lyase activity|L-citramalate hydrolase activity|citramalate dehydratase activity|mesaconate hydratase activity|(S)-2-methylmalate hydro-lyase (2-methylfumarate-forming)|mesaconate mesaconase activity				EC:4.2.1.34|KEGG_REACTION:R03693|MetaCyc:S-2-METHYLMALATE-DEHYDRATASE-RXN|RHEA:13529									molecular_function											owl:Class	
GO:0048504	biolink:NamedThing	regulation of timing of animal organ formation	Any process that modulates the rate, frequency or extent of animal organ formation at a consistent predetermined time point during development.	tmpzr1t_l9r_go_relaxed.owl	timing of organ biosynthesis|timing of organ formation													biological_process											owl:Class	
GO:2001057	biolink:NamedThing	reactive nitrogen species metabolic process	The chemical reactions and pathways involving a reactive nitrogen species.	tmpzr1t_l9r_go_relaxed.owl	RNS metabolism|RNS metabolic process|reactive nitrogen species metabolism							jl	2011-09-09T01:29:13Z					biological_process											owl:Class	
GO:0061344	biolink:NamedThing	regulation of cell adhesion involved in heart morphogenesis	Any process that modulates the extent of cell adhesion contributing to the shaping of the heart.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-09-29T11:35:27Z					biological_process											owl:Class	
GO:1901866	biolink:NamedThing	capsorubin biosynthetic process	The chemical reactions and pathways resulting in the formation of capsorubin.	tmpzr1t_l9r_go_relaxed.owl	capsorubin formation|capsorubin synthesis|capsorubin biosynthesis|capsorubin anabolism							yaf	2013-02-04T10:50:26Z					biological_process											owl:Class	
GO:0010221	biolink:NamedThing	negative regulation of vernalization response	Any process that stops, prevents or reduces the vernalization response, by which induction of flowering is normally caused by extended exposure to cold temperatures.	tmpzr1t_l9r_go_relaxed.owl	downregulation of vernalization response|down-regulation of vernalization response|inhibition of vernalization response|down regulation of vernalization response													biological_process											owl:Class	
GO:1990025	biolink:NamedThing	F bouton	Synaptic bouton found in the ventral horn of the spinal cord. F boutons range in diameter from 0.5 to 7 um and contain flattened or pleomorphic synaptic vesicles.	tmpzr1t_l9r_go_relaxed.owl					NIF_Subcellular:nlx_subcell_100206			pr	2013-02-06T10:29:42Z					cellular_component											owl:Class	
GO:0002609	biolink:NamedThing	positive regulation of myeloid dendritic cell antigen processing and presentation	Any process that activates or increases the frequency, rate, or extent of myeloid dendritic cell antigen processing and presentation.	tmpzr1t_l9r_go_relaxed.owl	activation of myeloid dendritic cell antigen processing and presentation|upregulation of myeloid dendritic cell antigen processing and presentation|up-regulation of myeloid dendritic cell antigen processing and presentation|stimulation of myeloid dendritic cell antigen processing and presentation|up regulation of myeloid dendritic cell antigen processing and presentation													biological_process											owl:Class	
GO:0099099	biolink:NamedThing	G-protein gated ion channel activity	An ion channel activity that is gated by binding of a G-protein beta-gamma dimer.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0102911	biolink:NamedThing	(-)-secoisolariciresinol dehydrogenase activity	Catalysis of the reaction: (-)-secoisolariciresinol + NAD <=> H+ + (-)-lactol + NADH.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-8680									molecular_function											owl:Class	
GO:0044812	biolink:NamedThing	fermentative hydrogen production	The fermentation of organic substances with a net release of hydrogen.	tmpzr1t_l9r_go_relaxed.owl	carbohydrate fermentation				Wikipedia:Fermentative_hydrogen_production			jl	2013-09-18T14:09:47Z					biological_process											owl:Class	
GO:2000648	biolink:NamedThing	positive regulation of stem cell proliferation	Any process that activates or increases the frequency, rate or extent of stem cell proliferation.	tmpzr1t_l9r_go_relaxed.owl								dph	2011-04-27T01:04:25Z					biological_process											owl:Class	
GO:0072091	biolink:NamedThing	regulation of stem cell proliferation	Any process that modulates the frequency, rate or extent of stem cell proliferation. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-02-08T02:09:03Z					biological_process											owl:Class	
GO:0008426	biolink:NamedThing	protein kinase C inhibitor activity	Binds to and stops, prevents or reduces the activity of protein kinase C, an enzyme which phosphorylates a protein.	tmpzr1t_l9r_go_relaxed.owl	PKC inhibitor activity|diacylglycerol-activated phospholipid-dependent protein kinase C inhibitor activity|diacylglycerol-activated phospholipid-dependent PKC inhibitor activity											GO:0004863		molecular_function											owl:Class	
GO:0071772	biolink:NamedThing	response to BMP	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bone morphogenetic protein (BMP) stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to BMP stimulus|response to bone morphogenetic protein stimulus							mah	2010-08-31T11:02:11Z					biological_process											owl:Class	
GO:0014731	biolink:NamedThing	spectrin-associated cytoskeleton	The part of the cytoskeleton composed of spectrin, protein 4.1 and ankyrin. Spectrin-associated cytoskeleton is associated with the plasma membrane.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0061784	biolink:NamedThing	peptidoglycan N-acetylglucosaminidase activity	Catalysis of the hydrolysis of (1->4)-beta linkages of N-acetyl-D-glucosamine (GlcNAc) from peptidoglycan.	tmpzr1t_l9r_go_relaxed.owl								dph	2016-09-07T16:17:03Z					molecular_function											owl:Class	
GO:0015929	biolink:NamedThing	hexosaminidase activity	Catalysis of the cleavage of hexosamine or N-acetylhexosamine residues (e.g. N-acetylglucosamine) residues from gangliosides or other glycoside oligosaccharides.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:3.2.1.52-RXN									molecular_function											owl:Class	
GO:0032690	biolink:NamedThing	negative regulation of interleukin-1 alpha production	Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-1 alpha production.	tmpzr1t_l9r_go_relaxed.owl	downregulation of interleukin-1 alpha production|negative regulation of IL-1 alpha production|down-regulation of interleukin-1 alpha production|inhibition of interleukin-1 alpha production|down regulation of interleukin-1 alpha production|negative regulation of interleukin-1 alpha secretion|negative regulation of interleukin-1 alpha biosynthetic process											GO:0050723|GO:0050712		biological_process											owl:Class	
GO:0032650	biolink:NamedThing	regulation of interleukin-1 alpha production	Any process that modulates the frequency, rate, or extent of interleukin-1 alpha production.	tmpzr1t_l9r_go_relaxed.owl	regulation of interleukin-1 alpha biosynthetic process|regulation of IL-1 alpha production|regulation of interleukin-1 alpha secretion											GO:0050721|GO:0050705		biological_process											owl:Class	
GO:1905655	biolink:NamedThing	negative regulation of artery smooth muscle contraction	Any process that stops, prevents or reduces the frequency, rate or extent of artery smooth muscle contraction.	tmpzr1t_l9r_go_relaxed.owl	inhibition of artery smooth muscle contraction|downregulation of artery smooth muscle contraction|down-regulation of artery smooth muscle contraction|down regulation of artery smooth muscle contraction							rph	2016-11-09T12:34:53Z					biological_process											owl:Class	
GO:0042612	biolink:NamedThing	MHC class I protein complex	A transmembrane protein complex composed of a MHC class I alpha chain and an invariant beta2-microglobin chain, and with or without a bound peptide antigen. Class I here refers to classical class I molecules.	tmpzr1t_l9r_go_relaxed.owl						See also the cellular component term 'MHC class I peptide loading complex ; GO:0042824'.								cellular_component											owl:Class	
GO:0042611	biolink:NamedThing	MHC protein complex	A transmembrane protein complex composed of an MHC alpha chain and, in most cases, either an MHC class II beta chain or an invariant beta2-microglobin chain, and with or without a bound peptide, lipid, or polysaccharide antigen.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0047674	biolink:NamedThing	apiose 1-reductase activity	Catalysis of the reaction: D-apiitol + NAD(+) = D-apiose + H(+) + NADH.	tmpzr1t_l9r_go_relaxed.owl	D-apiose reductase activity|D-apiitol reductase activity|D-apiitol:NAD+ 1-oxidoreductase activity				RHEA:15301|EC:1.1.1.114|KEGG_REACTION:R03577|MetaCyc:APIOSE-1-REDUCTASE-RXN									molecular_function											owl:Class	
GO:0070914	biolink:NamedThing	UV-damage excision repair	A DNA repair process that is initiated by an endonuclease that introduces a single-strand incision immediately 5' of a UV-induced damage site. UV-damage excision repair acts on both cyclobutane pyrimidine dimers (CPDs) and pyrimidine-pyrimidone 6-4 photoproducts (6-4PPs).	tmpzr1t_l9r_go_relaxed.owl	AER|alternative excision repair|UVER|UVDE-dependent excision repair|UV-damaged DNA endonuclease-dependent excision repair							mah	2009-09-10T03:14:06Z					biological_process											owl:Class	
GO:0032080	biolink:NamedThing	negative regulation of type I site-specific deoxyribonuclease activity	Any process that stops or reduces the rate of type I restriction endodeoxyribonuclease activity.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of type I restriction endodeoxyribonuclease activity|type I restriction enzyme inhibitor|type I restriction endodeoxyribonuclease inhibitor|down regulation of type I restriction endodeoxyribonuclease activity|inhibition of type I restriction endodeoxyribonuclease activity|downregulation of type I restriction endodeoxyribonuclease activity|down-regulation of type I restriction endodeoxyribonuclease activity													biological_process											owl:Class	
GO:0062210	biolink:NamedThing	shoot regeneration	The regeneration process by which a damaged or lost shoot regrows or re-differentiates. This process may occur via de-differentiation and subsequent reprogramming of somatic cells or activation of existing undifferentiated (meristematic) cells to produce a new shoot meristem and subsequently a new shoot.	tmpzr1t_l9r_go_relaxed.owl	shoot system regeneration							dph	2020-02-21T12:38:43Z					biological_process											owl:Class	
GO:0046068	biolink:NamedThing	cGMP metabolic process	The chemical reactions and pathways involving cyclic GMP, guanosine 3',5'-phosphate.	tmpzr1t_l9r_go_relaxed.owl	cGMP metabolism													biological_process											owl:Class	
GO:0050286	biolink:NamedThing	sorbitol-6-phosphatase activity	Catalysis of the reaction: D-glucitol 6-phosphate + H(2)O = D-glucitol + phosphate.	tmpzr1t_l9r_go_relaxed.owl	sorbitol-6-phosphate phosphohydrolase activity|sorbitol-6-phosphate phosphatase activity				EC:3.1.3.50|RHEA:24580|KEGG_REACTION:R02866|MetaCyc:SORBITOL-6-PHOSPHATASE-RXN									molecular_function											owl:Class	
GO:1905095	biolink:NamedThing	negative regulation of apolipoprotein A-I-mediated signaling pathway	Any process that stops, prevents or reduces the frequency, rate or extent of apolipoprotein A-I-mediated signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	inhibition of apolipoprotein A-I-mediated signaling pathway|negative regulation of apolipoprotein A-I-mediated signalling pathway|down regulation of apolipoprotein A-I-mediated signaling pathway|inhibition of apolipoprotein A-I-mediated signalling pathway|down-regulation of apolipoprotein A-I-mediated signalling pathway|downregulation of apolipoprotein A-I-mediated signaling pathway|downregulation of apolipoprotein A-I-mediated signalling pathway|down regulation of apolipoprotein A-I-mediated signalling pathway|down-regulation of apolipoprotein A-I-mediated signaling pathway							bc	2016-03-31T11:33:58Z					biological_process											owl:Class	
GO:0042430	biolink:NamedThing	indole-containing compound metabolic process	The chemical reactions and pathways involving compounds that contain an indole (2,3-benzopyrrole) skeleton.	tmpzr1t_l9r_go_relaxed.owl	ketole metabolism|indole and derivative metabolism|ketole metabolic process|indole-containing compound metabolism|indole derivative metabolic process|indole derivative metabolism|indole and derivative metabolic process											GO:0042434		biological_process											owl:Class	
GO:1901790	biolink:NamedThing	3-(2,3-dihydroxyphenyl)propanoate metabolic process	The chemical reactions and pathways involving 3-(2,3-dihydroxyphenyl)propanoate.	tmpzr1t_l9r_go_relaxed.owl	3-(2,3-dihydroxyphenyl)propanoate metabolism							yaf	2013-01-16T11:40:57Z					biological_process											owl:Class	
GO:0060651	biolink:NamedThing	regulation of epithelial cell proliferation involved in mammary gland bud elongation	Any process that modulates the frequency, rate or extent of mammary gland bud epithelial cell proliferation that results in the elongation of the bud.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-05-29T08:57:18Z					biological_process											owl:Class	
GO:2000560	biolink:NamedThing	positive regulation of CD24 production	Any process that activates or increases the frequency, rate or extent of CD24 biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of CD24 synthesis|positive regulation of CD24 anabolism|positive regulation of CD24 formation|positive regulation of CD24 biosynthetic process|positive regulation of CD24 biosynthesis							ebc	2011-04-03T08:57:02Z					biological_process											owl:Class	
GO:0008696	biolink:NamedThing	4-amino-4-deoxychorismate lyase activity	Catalysis of the reaction: 4-amino-4-deoxychorismate = 4-aminobenzoate + H(+) + pyruvate.	tmpzr1t_l9r_go_relaxed.owl	4-amino-4-deoxychorismate pyruvate-lyase (4-aminobenzoate-forming)|enzyme X activity|ADC lyase activity|aminodeoxychorismate lyase activity|para-aminobenzoic acid synthase|para-aminobenzoic acid (PABA) synthase|p-aminobenzoate synthetase|4-amino-4-deoxychorismate pyruvate-lyase activity				MetaCyc:ADCLY-RXN|KEGG_REACTION:R05553|RHEA:16201|EC:4.1.3.38	Note that the name 'para-amino benzoic acid synthase' was initially given to the 'aminodeoxychorismate synthase' activity before the additional 4-amino-4-deoxychorismate lyase activity was discovered. It is the lyase activity that actually produces para-aminobenzoic acid from 4-amino-4-deoxychorismate.								molecular_function											owl:Class	
GO:0140231	biolink:NamedThing	anterograde axonal transport of neurotransmitter receptor complex	The directed movement of a neurotransmitter receptor complex along microtubules from the cell body toward the cell periphery in nerve cell axons.	tmpzr1t_l9r_go_relaxed.owl								pg	2018-07-09T09:41:37Z					biological_process											owl:Class	
GO:0009385	biolink:NamedThing	N-acylmannosamine-6-phosphate 2-epimerase activity	Catalysis of the reaction: N-acetyl-D-mannosamine-6-phosphate = N-acetyl-D-glucosamine-6-phosphate.	tmpzr1t_l9r_go_relaxed.owl	N-acylmannosamine-6-P epimerase activity				MetaCyc:NANE-RXN|RHEA:25257|EC:5.1.3.9									molecular_function											owl:Class	
GO:1901111	biolink:NamedThing	actinorhodin catabolic process	The chemical reactions and pathways resulting in the breakdown of actinorhodin.	tmpzr1t_l9r_go_relaxed.owl	actinorhodin breakdown|actinorhodin catabolism|actinorhodin degradation							yaf	2012-07-11T03:06:00Z					biological_process											owl:Class	
GO:0045274	biolink:NamedThing	plasma membrane respiratory chain complex II	A part of the respiratory chain located in the plasma membrane, containing the four polypeptide subunits of succinate dehydrogenase, flavin-adenine dinucleotide and iron-sulfur. Catalyzes the oxidation of succinate by ubiquinone. Connects the TCA cycle with the respiratory chain. Examples of this component are found in bacterial species.	tmpzr1t_l9r_go_relaxed.owl	respiratory chain complex II													cellular_component											owl:Class	
GO:0010621	biolink:NamedThing	negative regulation of transcription by transcription factor localization	Any process that stops, prevents, or reduces the frequency, rate or extent of DNA-dependent transcription using a mechanism that involves the localization of a transcription factor.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of transcription by transcription factor localisation													biological_process											owl:Class	
GO:0106399	biolink:NamedThing	acyl-coenzyme A diphosphatase activity	Catalysis of the reaction: an acyl-CoA + H2O = adenosine 3',5'-bisphosphate + an acyl-4'-phosphopantetheine + 2 H(+).	tmpzr1t_l9r_go_relaxed.owl					RHEA:50044			hjd	2021-10-11T14:13:26Z					molecular_function											owl:Class	
GO:0042875	biolink:NamedThing	D-galactonate transmembrane transport	The process in which D-galactonate, the D-enantiomer of galactonate, is transported across a lipid bilayer, from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	D-galactonate transport													biological_process											owl:Class	
GO:0042873	biolink:NamedThing	aldonate transmembrane transport	The process in which aldonate is transported across a lipid bilayer, from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	aldonate transport													biological_process											owl:Class	
GO:2000564	biolink:NamedThing	regulation of CD8-positive, alpha-beta T cell proliferation	Any process that modulates the frequency, rate or extent of CD8-positive, alpha-beta T cell proliferation.	tmpzr1t_l9r_go_relaxed.owl								ebc	2011-04-03T09:03:13Z					biological_process											owl:Class	
GO:2000592	biolink:NamedThing	regulation of metanephric DCT cell differentiation	Any process that modulates the frequency, rate or extent of metanephric DCT cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	regulation of metanephric distal convoluted tubule cell differentiation							yaf	2011-04-11T01:40:33Z					biological_process											owl:Class	
GO:0140242	biolink:NamedThing	translation at postsynapse	Translation that occurs at the postsynapse.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/synapse/issues/210				Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.		pg	2018-07-15T09:26:27Z					biological_process											owl:Class	
GO:0060129	biolink:NamedThing	thyroid-stimulating hormone-secreting cell differentiation	The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a thyroid-stimulating hormone-secreting cell. A thyroid-stimulating hormone-secreting cell is a basophil cell of the anterior pituitary that produces thyroid-stimulating hormone, thyrotrophin.	tmpzr1t_l9r_go_relaxed.owl	TSH-secreting cell differentiation|thyrotroph differentiation|thyroid stimulating hormone secreting cell differentiation|beta-basophil differentiation|thyrotrope differentiation													biological_process											owl:Class	
GO:1902962	biolink:NamedThing	regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process	Any process that modulates the frequency, rate or extent of metalloendopeptidase activity involved in amyloid precursor protein catabolic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of metalloendoprotease activity involved in amyloid precursor protein catabolism|regulation of metalloendopeptidase activity involved in amyloid precursor protein degradation|regulation of metalloendoproteinase activity involved in amyloid precursor protein degradation|regulation of metalloendoprotease activity involved in amyloid precursor protein breakdown|regulation of metalloendoprotease activity involved in APP catabolic process|regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolism|regulation of metalloendoproteinase activity involved in APP catabolism|regulation of metalloendoproteinase activity involved in APP catabolic process|regulation of metalloendopeptidase activity involved in APP catabolic process|regulation of metalloendoproteinase activity involved in amyloid precursor protein catabolic process|regulation of metalloendoprotease activity involved in APP catabolism|regulation of metalloendoprotease activity involved in amyloid precursor protein degradation|regulation of metalloendoprotease activity involved in amyloid precursor protein catabolic process|regulation of metalloendopeptidase activity involved in APP catabolism|regulation of metalloendoproteinase activity involved in amyloid precursor protein breakdown|regulation of metalloendopeptidase activity involved in amyloid precursor protein breakdown|regulation of metalloendoproteinase activity involved in amyloid precursor protein catabolism							sjp	2014-05-06T09:11:55Z					biological_process											owl:Class	
GO:1901553	biolink:NamedThing	malonic acid transmembrane transport	The directed movement of malonic acid across a membrane.	tmpzr1t_l9r_go_relaxed.owl	malonic acid membrane transport					Note that this term is not intended for use in annotating lateral movement within membranes.		pr	2012-10-30T15:23:54Z					biological_process											owl:Class	
GO:2000826	biolink:NamedThing	regulation of heart morphogenesis	Any process that modulates the frequency, rate or extent of heart morphogenesis.	tmpzr1t_l9r_go_relaxed.owl	regulation of cardiac morphogenesis							vk	2011-07-19T10:08:58Z					biological_process											owl:Class	
GO:1904351	biolink:NamedThing	negative regulation of protein catabolic process in the vacuole	Any process that stops, prevents or reduces the frequency, rate or extent of protein catabolic process in the vacuole.	tmpzr1t_l9r_go_relaxed.owl	downregulation of protein catabolic process in the vacuole|down regulation of vacuolar protein degradation|inhibition of protein catabolic process in the vacuole|negative regulation of vacuolar protein catabolic process|inhibition of vacuolar protein breakdown|negative regulation of vacuolar protein breakdown|down-regulation of vacuolar protein breakdown|down regulation of protein catabolic process in the vacuole|down-regulation of protein catabolic process in the vacuole|down-regulation of vacuolar protein degradation|downregulation of vacuolar protein degradation|down regulation of vacuolar protein catabolism|inhibition of vacuolar protein catabolic process|down-regulation of vacuolar protein catabolic process|down regulation of vacuolar protein catabolic process|negative regulation of vacuolar protein degradation|inhibition of vacuolar protein degradation|down-regulation of vacuolar protein catabolism|down regulation of vacuolar protein breakdown|negative regulation of vacuolar protein catabolism|downregulation of vacuolar protein catabolic process|downregulation of vacuolar protein breakdown|inhibition of vacuolar protein catabolism|downregulation of vacuolar protein catabolism							rl	2015-06-12T09:10:42Z					biological_process											owl:Class	
GO:0061053	biolink:NamedThing	somite development	The progression of a somite from its initial formation to the mature structure. Somites are mesodermal clusters that are arranged segmentally along the anterior posterior axis of an embryo.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-03-02T12:05:13Z					biological_process											owl:Class	
GO:0072389	biolink:NamedThing	flavin adenine dinucleotide catabolic process	The chemical reactions and pathways resulting in the breakdown of flavin adenine dinucleotide, which acts as a coenzyme or prosthetic group of various flavoprotein oxidoreductase enzymes.	tmpzr1t_l9r_go_relaxed.owl	flavin adenine dinucleotide breakdown|flavin adenine dinucleotide catabolism|FAD or FADH2 catabolic process|flavin adenine dinucleotide degradation							mah	2010-12-02T04:28:02Z					biological_process											owl:Class	
GO:0042728	biolink:NamedThing	flavin-containing compound catabolic process	The chemical reactions and pathways resulting in the breakdown of a flavin, any derivative of the dimethylisoalloxazine (7,8-dimethylbenzo[g]pteridine-2,4(3H,10H)-dione) skeleton, with a substituent on the 10 position.	tmpzr1t_l9r_go_relaxed.owl	vitamin B2 and derivative catabolism|vitamin B2 and derivative catabolic process|flavin-containing compound catabolism|riboflavin and derivative catabolism|flavin-containing compound catabolic process breakdown|riboflavin and derivative catabolic process|flavin-containing compound catabolic process degradation													biological_process											owl:Class	
GO:0061324	biolink:NamedThing	canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation	The canonical Wnt signaling pathway that contributes to the modulation of the expansion of a population of cardiac outflow tract cells.	tmpzr1t_l9r_go_relaxed.owl	canonical Wnt-activated signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation|canonical Wnt receptor signalling pathway involved in positive regulation of cardiac outflow tract cell proliferation|canonical Wnt receptor signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation							dph	2010-09-28T09:19:37Z					biological_process											owl:Class	
GO:0010973	biolink:NamedThing	positive regulation of division septum assembly	Any process that increases the frequency, rate or extent of division septum formation. division septum formation is the assembly and arrangement of a septum that spans the plasma membrane interface between progeny cells following cytokinesis.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of division septum formation|positive regulation of division septum formation involved in cell cycle cytokinesis|upregulation of mitotic division septum assembly							tb	2009-06-01T10:27:15Z			GO:1902470|GO:1901912		biological_process											owl:Class	
GO:0075218	biolink:NamedThing	zoospore encystment on host	The physiological, developmental and morphological changes that occur in a symbiont zoospore during the process of its encystment. Encystment means to enter a state of essentially suspended animation in which the spore is protected by an outer coating and remains immobile and inactive until favorable conditions for growth occur again. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0010311	biolink:NamedThing	lateral root formation	The process that gives rise to a lateral root. This process pertains to the initial formation of a structure from unspecified parts. A lateral root primordium represents an organized group of cells derived from the root pericycle that will differentiate into a new root, as opposed to the initiation of the main root from the embryo proper.	tmpzr1t_l9r_go_relaxed.owl	lateral root primordium development											GO:0010386		biological_process											owl:Class	
GO:0043834	biolink:NamedThing	trimethylamine methyltransferase activity	Catalysis of the reaction: trimethylamine + a trimethylamine corrinoid protein = a methylated trimethylamine corrinoid protein + dimethylamine.	tmpzr1t_l9r_go_relaxed.owl	MT1|trimethylamine-specific methylcobalamin:coenzyme M methyltransferase activity|TMA methyltransferase 1|trimethylamine:corrinoid methyltransferase activity|mttB1				MetaCyc:RXN-8102|RHEA:39287|EC:2.1.1.250	This function is the first step in the pathway of methanogenesis from trimethylamine.								molecular_function											owl:Class	
GO:0050739	biolink:NamedThing	peptide cross-linking via S-[5'-(L-tryptoph-6'-yl)-L-tyrosin-3'-yl]-L-methionin-S-ium	The cross-linking of a tyrosine residue to a tryptophan residue and a methionine residue to form S-[5'-(L-tryptoph-6'-yl)-L-tyrosin-3'-yl]-L-methionin-S-ium.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0348									biological_process											owl:Class	
GO:0071901	biolink:NamedThing	negative regulation of protein serine/threonine kinase activity	Any process that decreases the rate, frequency, or extent of protein serine/threonine kinase activity.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-09-15T03:09:43Z					biological_process											owl:Class	
GO:0004161	biolink:NamedThing	dimethylallyltranstransferase activity	Catalysis of the reaction: dimethylallyl diphosphate + isopentenyl diphosphate = diphosphate + geranyl diphosphate.	tmpzr1t_l9r_go_relaxed.owl	geranyl diphosphate synthase|(2E,6E)-farnesyl diphosphate synthetase activity|dimethylallyltransferase activity|trans-farnesyl pyrophosphate synthetase activity|DMAPP:IPP-dimethylallyltransferase activity|diprenyltransferase activity|dimethylallyl-diphosphate:isopentenyl-diphosphate dimethylallyltranstransferase activity|geranyl pyrophosphate synthetase activity|geranyl-diphosphate synthase activity|geranyl pyrophosphate synthase activity				EC:2.5.1.1|MetaCyc:GPPSYN-RXN|RHEA:22408|Reactome:R-HSA-191322	Note that this is the first step in the formation of farnesyl diphosphate. The second step is 'geranyltranstransferase activity ; GO:0004337'. Consider also annotating to the biological process term 'farnesyl diphosphate biosynthetic process ; GO:0045337'.								molecular_function											owl:Class	
GO:0007181	biolink:NamedThing	transforming growth factor beta receptor complex assembly	The aggregation, arrangement and bonding together of a ligand-bound type II transforming growth factor beta (TGF-beta) receptor dimer with a type I TGF-beta receptor dimer, following ligand binding, to form a heterotetrameric TGF-beta receptor complex.	tmpzr1t_l9r_go_relaxed.owl	TGFbeta receptor complex assembly|TGF-beta:type II receptor:type I receptor complex assembly|TGF-beta receptor complex assembly													biological_process											owl:Class	
GO:0016335	biolink:NamedThing	morphogenesis of larval imaginal disc epithelium	The process in which the anatomical structures of a larval imaginal disc epithelium are generated and organized.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1902688	biolink:NamedThing	regulation of NAD metabolic process	Any process that modulates the frequency, rate or extent of NAD metabolic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of NAD metabolism|regulation of oxidized NAD metabolism|regulation of NAD (oxidized) metabolic process|regulation of oxidized nicotinamide adenine dinucleotide metabolism|regulation of oxidized NAD metabolic process|regulation of NAD (oxidized) metabolism|regulation of nicotinamide adenine dinucleotide metabolic process|regulation of NAD phosphorylation and dephosphorylation|regulation of nicotinamide adenine dinucleotide metabolism|regulation of oxidized nicotinamide adenine dinucleotide metabolic process							di	2014-02-12T18:58:50Z					biological_process											owl:Class	
GO:0036384	biolink:NamedThing	cytidine-diphosphatase activity	Catalysis of the reaction: CDP + H2O = CMP + phosphate.	tmpzr1t_l9r_go_relaxed.owl	CDPase activity				RHEA:64880			bf	2013-05-23T13:33:01Z					molecular_function											owl:Class	
GO:0035375	biolink:NamedThing	zymogen binding	Binding to a zymogen, an enzymatically inactive precursor of an enzyme that is often convertible to an active enzyme by proteolysis.	tmpzr1t_l9r_go_relaxed.owl	proenzyme binding							bf	2010-03-18T10:50:35Z					molecular_function											owl:Class	
GO:0050013	biolink:NamedThing	2-dehydropantoate aldolase activity	Catalysis of the reaction: 2-dehydropantoate = 3-methyl-2-oxobutanoate + formaldehyde.	tmpzr1t_l9r_go_relaxed.owl	ketopantoaldolase activity|2-dehydropantoate formaldehyde-lyase activity|2-dehydropantoate formaldehyde-lyase (3-methyl-2-oxobutanoate-forming)				RHEA:23276|EC:4.1.2.12|MetaCyc:KETOPANTOALDOLASE-RXN									molecular_function											owl:Class	
GO:0002761	biolink:NamedThing	regulation of myeloid leukocyte differentiation	Any process that modulates the frequency, rate, or extent of myeloid leukocyte differentiation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0010293	biolink:NamedThing	abscisic aldehyde oxidase activity	Catalysis of the reaction: (+)-abscisic aldehyde + H(2)O + O(2) = abscisate + H(2)O(2) + H(+).	tmpzr1t_l9r_go_relaxed.owl	abscisic-aldehyde:oxygen oxidoreductase activity|AAO3|abscisic-aldehyde oxidase activity|AOdelta				RHEA:20529|MetaCyc:1.2.3.14-RXN|EC:1.2.3.14|KEGG_REACTION:R06957							GO:0033725		molecular_function											owl:Class	
GO:0018488	biolink:NamedThing	aryl-aldehyde oxidase activity	Catalysis of the reaction: an aromatic aldehyde + O2 + H2O = an aromatic acid + hydrogen peroxide.	tmpzr1t_l9r_go_relaxed.owl	aryl-aldehyde:oxygen oxidoreductase activity				UM-BBD_reactionID:r0145|RHEA:18569|EC:1.2.3.9|MetaCyc:ARYL-ALDEHYDE-OXIDASE-RXN									molecular_function											owl:Class	
GO:1990729	biolink:NamedThing	primary miRNA modification	The covalent alteration of one or more nucleotides within a primary miRNA molecule to produce a primary miRNA molecule with a sequence that differs from that coded genetically.	tmpzr1t_l9r_go_relaxed.owl								sp	2015-04-16T06:19:22Z					biological_process											owl:Class	
GO:0014828	biolink:NamedThing	distal stomach smooth muscle contraction	A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the distal stomach. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The distal stomach is composed of the lower body and antrum and develops strong peristaltic phasic contractions that increase in amplitude as they propagate toward the pylorus.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0014821	biolink:NamedThing	phasic smooth muscle contraction	A process in which force is generated within phasic smooth muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. In the phasic smooth muscle, the muscle contraction occurs without an ordered sarcomeric structure. Phasic smooth muscle contraction occurs in a series of discrete contractions and relaxations.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0033141	biolink:NamedThing	positive regulation of peptidyl-serine phosphorylation of STAT protein	Any process that activates or increases the frequency, rate or extent of the phosphorylation of a serine residue of a STAT (Signal Transducer and Activator of Transcription) protein.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of serine phosphorylation of STAT3 protein|upregulation of serine phosphorylation of STAT3 protein|activation of serine phosphorylation of STAT3 protein|up regulation of serine phosphorylation of STAT3 protein|positive regulation of serine phosphorylation of STAT3 protein											GO:1903263		biological_process											owl:Class	
GO:0033139	biolink:NamedThing	regulation of peptidyl-serine phosphorylation of STAT protein	Any process that modulates the frequency, rate or extent of the phosphorylation of a serine residue of a STAT (Signal Transducer and Activator of Transcription) protein.	tmpzr1t_l9r_go_relaxed.owl	regulation of serine phosphorylation of STAT3 protein							mr	2014-08-06T21:22:57Z			GO:1903261		biological_process											owl:Class	
GO:0071050	biolink:NamedThing	sno(s)RNA polyadenylation	The enzymatic addition of a sequence of adenylyl residues at the 3' end of snoRNA class molecule (referred to as an sRNA in Archaea). In eukaryotes, this occurs in conjunction with termination of transcription of precursor snoRNA molecules and may occur post-transcriptionally on incorrectly processed molecules targeted for degradation.	tmpzr1t_l9r_go_relaxed.owl	sRNA polyadenylation|snoRNA polyadenylation	https://github.com/geneontology/go-ontology/issues/20416						krc	2009-08-25T03:33:44Z					biological_process											owl:Class	
GO:0031126	biolink:NamedThing	sno(s)RNA 3'-end processing	Any process involved in forming the mature 3' end of a snoRNA family molecule, also referred to as an sRNA in Archaea.	tmpzr1t_l9r_go_relaxed.owl	sno(s)RNA 3' end processing|snoRNA 3'-end processing|sRNA 3'-end processing	https://github.com/geneontology/go-ontology/issues/20416												biological_process											owl:Class	
GO:0006005	biolink:NamedThing	L-fucose biosynthetic process	The chemical reactions and pathways resulting in the formation of L-fucose (6-deoxy-L-galactose).	tmpzr1t_l9r_go_relaxed.owl	L-fucose synthesis|L-fucose biosynthesis|L-fucose anabolism|L-fucose formation													biological_process											owl:Class	
GO:0051086	biolink:NamedThing	chaperone mediated protein folding independent of cofactor	The process of assisting in the correct noncovalent assembly of posttranslational proteins and does not depend on additional protein cofactors. This function occurs over one or more cycles of nucleotide-dependent binding and release.	tmpzr1t_l9r_go_relaxed.owl	chaperone cofactor-independent protein folding													biological_process											owl:Class	
GO:0051084	biolink:NamedThing	'de novo' posttranslational protein folding	The process of assisting in the correct noncovalent folding of newly formed polypeptides or folding intermediates of polypeptides that have exited the ribosome and/or have been stabilized and transferred by other chaperone proteins. This process could involve several cycles of ATP hydrolysis.	tmpzr1t_l9r_go_relaxed.owl	'de novo' post-translational protein folding													biological_process											owl:Class	
GO:1900517	biolink:NamedThing	positive regulation of xylose catabolic process to ethanol	Any process that activates or increases the frequency, rate or extent of xylose catabolic process to ethanol.	tmpzr1t_l9r_go_relaxed.owl	upregulation of xylose catabolic process to ethanol|upregulation of xylose catabolism to ethanol|positive regulation of xylose catabolism to ethanol|activation of xylose catabolism to ethanol|up-regulation of xylose catabolic process to ethanol|up regulation of xylose catabolic process to ethanol|up regulation of xylose catabolism to ethanol|activation of xylose catabolic process to ethanol|up-regulation of xylose catabolism to ethanol							tt	2012-05-02T04:09:26Z					biological_process											owl:Class	
GO:0071133	biolink:NamedThing	alpha9-beta1 integrin-ADAM8 complex	A protein complex that consists of an alpha9-beta1 integrin complex bound to the transmembrane metallopeptidase ADAM8.	tmpzr1t_l9r_go_relaxed.owl	ITGA9-ITGB1-ADAM8 complex							mah	2009-11-13T02:28:49Z					cellular_component											owl:Class	
GO:0004782	biolink:NamedThing	sulfinoalanine decarboxylase activity	Catalysis of the reaction: 3-sulfino-L-alanine = hypotaurine + CO2.	tmpzr1t_l9r_go_relaxed.owl	cysteic decarboxylase activity|cysteinesulfinate decarboxylase activity|cysteine-sulfinate decarboxylase activity|sulphinoalanine decarboxylase activity|CSADCase activity|CADCase/CSADCase activity|L-cysteinesulfinic acid decarboxylase activity|3-sulfino-L-alanine carboxy-lyase (hypotaurine-forming)|3-sulfino-L-alanine carboxy-lyase activity|CSAD|sulfoalanine decarboxylase activity|cysteinesulfinic acid decarboxylase activity				MetaCyc:SULFINOALANINE-DECARBOXYLASE-RXN|Reactome:R-HSA-1655443|EC:4.1.1.29|RHEA:16877									molecular_function											owl:Class	
GO:1903766	biolink:NamedThing	positive regulation of potassium ion export across plasma membrane	Any process that activates or increases the frequency, rate or extent of potassium ion export across the plasma membrane.	tmpzr1t_l9r_go_relaxed.owl	upregulation of potassium ion export|up-regulation of potassium ion export across plasma membrane|up-regulation of potassium ion export|upregulation of potassium ion export across plasma membrane|positive regulation of potassium ion export|activation of potassium ion export|up regulation of potassium export|up regulation of potassium ion export across plasma membrane|positive regulation of potassium export|activation of potassium export|up-regulation of potassium export|activation of potassium ion export across plasma membrane|up regulation of potassium ion export|upregulation of potassium export							rl	2013-07-17T16:40:10Z			GO:1902304		biological_process											owl:Class	
GO:0018823	biolink:NamedThing	cyclohexa-1,5-dienecarbonyl-CoA hydratase activity	Catalysis of the reaction: cyclohexa-1,5-diene-1-carbonyl-CoA + H(2)O = 6-hydroxycyclohex-1-enecarbonyl-CoA.	tmpzr1t_l9r_go_relaxed.owl	6-hydroxycyclohex-1-enecarbonyl-CoA (cyclohexa-1,5-dienecarbonyl-CoA-forming)|cyclohexa-1,5-dienecarbonyl-CoA hydro-lyase activity|dienoyl-CoA hydratase activity|cyclohex-1,5-diene-1-carbonyl-CoA hydratase activity|cyclohexa-1,5-diene-1-carbonyl-CoA hydratase activity|cyclohexa-1,5-diene-1-carboxyl-CoA hydratase activity				UM-BBD_reactionID:r0203|KEGG_REACTION:R05597|RHEA:21856|MetaCyc:4.2.1.100-RXN|EC:4.2.1.100									molecular_function											owl:Class	
GO:0097510	biolink:NamedThing	base-excision repair, AP site formation via deaminated base removal	A base-excision repair, AP site formation process occurring via excision of a deaminated base.	tmpzr1t_l9r_go_relaxed.owl								pr	2013-10-08T14:44:01Z					biological_process											owl:Class	
GO:0006285	biolink:NamedThing	base-excision repair, AP site formation	The formation of an AP site, a deoxyribose sugar with a missing base, by DNA glycosylase which recognizes an altered base in DNA and catalyzes its hydrolytic removal. This sugar phosphate is the substrate recognized by the AP endonuclease, which cuts the DNA phosphodiester backbone at the 5' side of the altered site to leave a gap which is subsequently repaired.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0090320	biolink:NamedThing	regulation of chylomicron remnant clearance	Any process that modulates the rate, frequency or extent of chylomicron remnant clearance. Chylomicron clearance is the process in which a chylomicron remnant is removed from the blood via receptor-mediated endocytosis into liver cells and its constituent parts degraded.	tmpzr1t_l9r_go_relaxed.owl								tb	2010-04-30T10:20:26Z					biological_process											owl:Class	
GO:0080021	biolink:NamedThing	response to benzoic acid	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a benzoic acid stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to benzoic acid stimulus													biological_process											owl:Class	
GO:0032553	biolink:NamedThing	ribonucleotide binding	Binding to a ribonucleotide, any compound consisting of a ribonucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose moiety.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0007137	biolink:NamedThing	meiotic metaphase II	The cell cycle phase, following prophase II, during which chromosomes become aligned on the equatorial plate of the cell as part of meiosis II.	tmpzr1t_l9r_go_relaxed.owl						Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).								biological_process											owl:Class	
GO:0093002	biolink:NamedThing	response to nematicide	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nematicide stimulus. Nematicides are chemicals used to kill nematodes.	tmpzr1t_l9r_go_relaxed.owl	response to nematocide|response to antihelmintic													biological_process											owl:Class	
GO:1901320	biolink:NamedThing	negative regulation of heart induction	Any process that stops, prevents or reduces the frequency, rate or extent of heart induction.	tmpzr1t_l9r_go_relaxed.owl	downregulation of heart induction|down-regulation of heart induction|down regulation of heart induction|inhibition of heart induction							bf	2012-08-28T15:48:38Z					biological_process											owl:Class	
GO:0043099	biolink:NamedThing	pyrimidine deoxyribonucleoside salvage	Any process that generates a pyrimidine deoxyribonucleoside from derivatives of it, without de novo synthesis.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1903228	biolink:NamedThing	xanthosine catabolic process	The chemical reactions and pathways resulting in the breakdown of xanthosine.	tmpzr1t_l9r_go_relaxed.owl	xanthosine catabolism|xanthosine degradation|xanthosine breakdown							jl	2014-07-31T09:21:52Z					biological_process											owl:Class	
GO:1903227	biolink:NamedThing	xanthosine metabolic process	The chemical reactions and pathways involving xanthosine.	tmpzr1t_l9r_go_relaxed.owl	xanthosine metabolism							jl	2014-07-31T09:21:46Z					biological_process											owl:Class	
GO:0015401	biolink:NamedThing	urea:sodium symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: urea(out) + Na+(out) = urea(in) + Na+(in).	tmpzr1t_l9r_go_relaxed.owl	urea active transmembrane transporter activity													molecular_function											owl:Class	
GO:1905320	biolink:NamedThing	regulation of mesenchymal stem cell migration	Any process that modulates the frequency, rate or extent of mesenchymal stem cell migration.	tmpzr1t_l9r_go_relaxed.owl								sl	2016-07-15T22:19:14Z					biological_process											owl:Class	
GO:0016964	biolink:NamedThing	alpha-2 macroglobulin receptor activity	Combining with alpha-2 macroglobulin and delivering alpha-2 macroglobulin into the cell via receptor-mediated endocytosis.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0044060	biolink:NamedThing	regulation of endocrine process	Any process that modulates the frequency, rate or extent of an endocrine process, a process involving the secretion of or response to endocrine hormones. An endocrine hormone is a hormone released into the circulatory system.	tmpzr1t_l9r_go_relaxed.owl	regulation of endocrine system process													biological_process											owl:Class	
GO:0003345	biolink:NamedThing	proepicardium cell migration involved in pericardium morphogenesis	The coordinated movement of a mesenchymal proepicardial cell to the surface of the developing heart.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-12-01T10:49:32Z					biological_process											owl:Class	
GO:0021675	biolink:NamedThing	nerve development	The process whose specific outcome is the progression of a nerve over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0017101	biolink:NamedThing	aminoacyl-tRNA synthetase multienzyme complex	A multienzyme complex found in all multicellular eukaryotes composed of eight proteins with aminoacyl-tRNA synthetase activities (abbreviated as: ArgRS, AspRS, GluProRS, GlnRS, IleRS, LeuRS, LysRS, MetRS where RS is the enzyme, preceded by the amino acid it uses as a substrate) as well as three non-synthetase proteins (p43, p38, and p18) with diverse functions. Several of these subunits are known dimers, so the total polypeptide count in the multisynthetase complex is at least fifteen. All of the enzymes in this assembly catalyze the same reaction, the covalent attachment of an amino acid to either the 2'- or 3'-hydroxyl of the 3'-terminal adenosine of tRNA, but using different substrates.	tmpzr1t_l9r_go_relaxed.owl	aminoacyl-tRNA synthetase complex|multisynthetase complex													cellular_component											owl:Class	
GO:0048447	biolink:NamedThing	sepal morphogenesis	The process in which the anatomical structures of the sepal are generated and organized.	tmpzr1t_l9r_go_relaxed.owl												GO:0048422		biological_process											owl:Class	
GO:0048444	biolink:NamedThing	floral organ morphogenesis	The process in which the anatomical structures of the floral organ are generated and organized.	tmpzr1t_l9r_go_relaxed.owl												GO:0048434		biological_process											owl:Class	
GO:0140062	biolink:NamedThing	5-formylcytosine dioxygenase activity	Catalysis of the reaction: 5-formylcytosine+ 2-oxoglutarate + O2 = 5-carboxylcytosine + succinate + CO2.	tmpzr1t_l9r_go_relaxed.owl	5fC dioxygenase							pg	2017-07-20T09:57:16Z					molecular_function											owl:Class	
GO:0015488	biolink:NamedThing	glucuronide:cation symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucuronide(out) + monovalent cation(out) = glucuronide(in) + monovalent cation(in).	tmpzr1t_l9r_go_relaxed.owl	glucuronide:monovalent cation symporter activity|glucuronoside permease activity													molecular_function											owl:Class	
GO:0015486	biolink:NamedThing	glycoside-pentoside-hexuronide:cation symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: (glycoside, pentoside or hexuronide)(out) + monovalent cation(out) = (glycoside, pentoside or hexuronide)(in) + monovalent cation(in). The cation is Na+, Li+ or H+.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0060907	biolink:NamedThing	positive regulation of macrophage cytokine production	Any process that increases the rate, frequency or extent of macrophage cytokine production. Macrophage cytokine production is the appearance of a chemokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-09-04T02:32:18Z					biological_process											owl:Class	
GO:0061081	biolink:NamedThing	positive regulation of myeloid leukocyte cytokine production involved in immune response	Any process that modulates the rate, frequency, or extent of the production of a cytokine that contributes to the immune response.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of myeloid cell cytokine production involved in immune response							dph	2010-04-13T11:26:41Z					biological_process											owl:Class	
GO:0086029	biolink:NamedThing	Purkinje myocyte to ventricular cardiac muscle cell signaling	Any process that mediates the transfer of information from a Purkinje myocyte to a ventricular cardiac muscle cell.	tmpzr1t_l9r_go_relaxed.owl	Purkinje myocyte to ventricular cardiac muscle cell signalling							tb	2011-11-11T02:02:14Z					biological_process											owl:Class	
GO:0001514	biolink:NamedThing	selenocysteine incorporation	The incorporation of selenocysteine into a peptide; uses a special tRNA that recognizes the UGA codon as selenocysteine, rather than as a termination codon. Selenocysteine is synthesized from serine before its incorporation; it is not a posttranslational modification of peptidyl-cysteine.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0022									biological_process											owl:Class	
GO:0006451	biolink:NamedThing	translational readthrough	The continuation of translation beyond a stop codon by the use of a special tRNA that recognizes the UAG and UGA codons as modified amino acids, rather than as termination codons.	tmpzr1t_l9r_go_relaxed.owl	natural nonsense suppression													biological_process											owl:Class	
GO:0034256	biolink:NamedThing	chlorophyll(ide) b reductase activity	Catalysis of the reaction: 71-hydroxychlorophyll(ide) a + NAD(P)+ = chlorophyll(ide) b + NAD(P)H + H+.	tmpzr1t_l9r_go_relaxed.owl	Chl b reductase activity|chlorophyllide b reductase activity|chlorophyll b reductase activity				MetaCyc:RXN-7678|EC:1.1.1.294									molecular_function											owl:Class	
GO:0006581	biolink:NamedThing	acetylcholine catabolic process	The chemical reactions and pathways resulting in the breakdown of acetylcholine, the acetic acid ester of the organic base choline.	tmpzr1t_l9r_go_relaxed.owl	acetylcholine catabolism|acetylcholine degradation|acetylcholine breakdown													biological_process											owl:Class	
GO:0071610	biolink:NamedThing	chemokine (C-C motif) ligand 1 production	The appearance of chemokine (C-C motif) ligand 1 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	tmpzr1t_l9r_go_relaxed.owl	T cell activation 3 production|CCL1 production|TCA-3 production							mah	2010-02-05T04:35:00Z					biological_process											owl:Class	
GO:1905749	biolink:NamedThing	regulation of endosome to plasma membrane protein transport	Any process that modulates the frequency, rate or extent of endosome to plasma membrane protein transport.	tmpzr1t_l9r_go_relaxed.owl								pga	2016-12-09T13:46:13Z					biological_process											owl:Class	
GO:0060137	biolink:NamedThing	maternal process involved in parturition	A reproductive process occurring in the mother that results in birth.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0102427	biolink:NamedThing	allocryptopine 6-hydroxylase activity	Catalysis of the reaction: allocryptopine + NADPH + O2 + H+ <=> 6-hydroxy-allocryptopine + NADP + H2O.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-13828									molecular_function											owl:Class	
GO:0061838	biolink:NamedThing	CENP-T-W-S-X complex	A histone-variant containing protein complex which forms a centromere specific nucleosomal structure, involved in centromeric chromatin organization.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0102321	biolink:NamedThing	2,2'-hydroxybiphenyl monooxygenase activity	Catalysis of the reaction: biphenyl-2,2'-diol + O2 + NADH + H+ <=> biphenyl-2,2',3-triol + H2O + NAD.	tmpzr1t_l9r_go_relaxed.owl					RHEA:63512|EC:1.14.13.44|MetaCyc:MONOMER-17239									molecular_function											owl:Class	
GO:0006078	biolink:NamedThing	(1->6)-beta-D-glucan biosynthetic process	The chemical reactions and pathways resulting in the formation of (1->6)-beta-D-glucans.	tmpzr1t_l9r_go_relaxed.owl	1,6-beta-glucan formation|beta-1,6 glucan biosynthesis|1,6-beta-glucan anabolism|beta-1,6 glucan formation|1,6-beta-glucan synthesis|beta-1,6 glucan biosynthetic process|beta-1,6 glucan anabolism|beta-1,6 glucan synthesis|1,6-beta-glucan biosynthetic process|1,6-beta-glucan biosynthesis													biological_process											owl:Class	
GO:0006077	biolink:NamedThing	(1->6)-beta-D-glucan metabolic process	The chemical reactions and pathways involving (1->6)-beta-D-glucans, compounds composed of glucose residues linked by (1->6)-beta-D-glucosidic bonds.	tmpzr1t_l9r_go_relaxed.owl	1,6-beta-glucan metabolism|beta-1,6 glucan metabolism|beta-1,6 glucan metabolic process|1,6-beta-glucan metabolic process													biological_process											owl:Class	
GO:1900897	biolink:NamedThing	negative regulation of heptadecane biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of heptadecane biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of heptadecane biosynthesis|downregulation of heptadecane synthesis|inhibition of heptadecane biosynthetic process|negative regulation of heptadecane synthesis|inhibition of heptadecane formation|down regulation of heptadecane formation|inhibition of heptadecane biosynthesis|negative regulation of heptadecane formation|inhibition of heptadecane anabolism|downregulation of heptadecane biosynthesis|inhibition of heptadecane synthesis|down regulation of heptadecane synthesis|down-regulation of heptadecane formation|downregulation of heptadecane formation|downregulation of heptadecane biosynthetic process|down regulation of heptadecane biosynthesis|down regulation of heptadecane anabolism|down-regulation of heptadecane biosynthesis|down regulation of heptadecane biosynthetic process|down-regulation of heptadecane biosynthetic process|negative regulation of heptadecane anabolism|down-regulation of heptadecane synthesis|down-regulation of heptadecane anabolism|downregulation of heptadecane anabolism							tt	2012-06-13T03:28:02Z					biological_process											owl:Class	
GO:0018925	biolink:NamedThing	m-cresol metabolic process	The chemical reactions and pathways involving m-cresol (3-hydroxytoluene), the meta-isoform of cresol. Used to produce agricultural chemicals, and in specialty resins, pharmaceuticals and pressure-sensitive dyes.	tmpzr1t_l9r_go_relaxed.owl	meta-cresol metabolism|3-hydroxytoluene metabolic process|meta-cresol metabolic process|m-cresol metabolism|3-hydroxytoluene metabolism				UM-BBD_pathwayID:mcr|MetaCyc:M-CRESOL-DEGRADATION-PWY									biological_process											owl:Class	
GO:0042212	biolink:NamedThing	cresol metabolic process	The chemical reactions and pathways involving cresol, a mixture of the aromatic alcohol isoforms o-, p-, and m-cresol, which is obtained from coal tar or petroleum. The isomers are used as disinfectants, textile scouring agents, surfactants and as intermediates in the manufacture of salicylaldehyde, coumarin, and herbicides as well as being a major component of creosote.	tmpzr1t_l9r_go_relaxed.owl	hydroxytoluene metabolism|cresol metabolism|hydroxytoluene metabolic process													biological_process											owl:Class	
GO:0018724	biolink:NamedThing	4-phenanthrol sulfotransferase activity	Catalysis of the reaction: 4-phenanthrol + X-SO3(-) = HX + 4-phenanthrylsulfate.	tmpzr1t_l9r_go_relaxed.owl	4-phenanthrol sulphotransferase activity				UM-BBD_reactionID:r0562									molecular_function											owl:Class	
GO:0019111	biolink:NamedThing	phenanthrol sulfotransferase activity	Catalysis of the reaction: phenanthrol + X-SO3(-) = HX + phenanthrylsulfate.	tmpzr1t_l9r_go_relaxed.owl	phenanthrol sulphotransferase activity													molecular_function											owl:Class	
GO:0021870	biolink:NamedThing	Cajal-Retzius cell differentiation	The process in which a neuroblast acquires specialized structural and/or functional features of a Cajal-Retzius cell, one of a transient population of pioneering neurons in the cerebral cortex. These cells are slender bipolar cells of the developing marginal zone. One feature of these cells in mammals is that they express the Reelin gene.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0051542	biolink:NamedThing	elastin biosynthetic process	The chemical reactions and pathways resulting in the formation of elastin, a fibrous glycoprotein found in elastic tissues such as the walls of arteries.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0051541	biolink:NamedThing	elastin metabolic process	The chemical reactions and pathways involving elastin, a glycoprotein which is randomly coiled and crosslinked to form elastic fibers that are found in connective tissue.	tmpzr1t_l9r_go_relaxed.owl	elastin metabolism													biological_process											owl:Class	
GO:0150151	biolink:NamedThing	regulation of interleukin-17A production	Any process that modulates the frequency, rate or extent of interleukin-17A production.	tmpzr1t_l9r_go_relaxed.owl	regulation of interleukin-17A biosynthetic process							bc	2019-12-11T07:44:52Z					biological_process											owl:Class	
GO:0070484	biolink:NamedThing	dehydro-D-arabinono-1,4-lactone metabolic process	The chemical reactions and pathways involving dehydro-D-arabinono-1,4-lactone, the gamma-lactone (5R)-3,4-dihydroxy-5-(hydroxymethyl)furan-2(5H)-one.	tmpzr1t_l9r_go_relaxed.owl	dehydro-D-arabinono-1,4-lactone metabolism													biological_process											owl:Class	
GO:0009793	biolink:NamedThing	embryo development ending in seed dormancy	The process whose specific outcome is the progression of the embryo over time, from zygote formation to the end of seed dormancy. An example of this process is found in Arabidopsis thaliana.	tmpzr1t_l9r_go_relaxed.owl	embryogenesis													biological_process											owl:Class	
GO:0106022	biolink:NamedThing	positive regulation of vesicle docking	Any process that activates or increases the frequency, rate or extent of vesicle docking.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of vesicle to membrane docking							hjd	2017-05-16T14:12:32Z					biological_process											owl:Class	
GO:1902943	biolink:NamedThing	positive regulation of voltage-gated chloride channel activity	Any process that activates or increases the frequency, rate or extent of voltage-gated chloride channel activity.	tmpzr1t_l9r_go_relaxed.owl	upregulation of voltage-dependent chloride channel activity|up regulation of voltage-gated chloride channel activity|activation of voltage-dependent chloride channel activity|up-regulation of voltage-dependent chloride channel activity|positive regulation of voltage gated chloride channel activity|upregulation of voltage-gated chloride channel activity|upregulation of voltage gated chloride channel activity|positive regulation of voltage-dependent chloride channel activity|up regulation of voltage gated chloride channel activity|up regulation of voltage-dependent chloride channel activity|activation of voltage gated chloride channel activity|activation of voltage-gated chloride channel activity|up-regulation of voltage-gated chloride channel activity|up-regulation of voltage gated chloride channel activity							als	2014-04-28T08:55:43Z					biological_process											owl:Class	
GO:2001146	biolink:NamedThing	positive regulation of phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity	Any process that activates or increases the frequency, rate or extent of phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity.	tmpzr1t_l9r_go_relaxed.owl								yaf	2011-10-19T10:41:30Z					biological_process											owl:Class	
GO:0042174	biolink:NamedThing	negative regulation of sporulation resulting in formation of a cellular spore	Any process that stops, prevents, or reduces the frequency, rate or extent of sporulation.	tmpzr1t_l9r_go_relaxed.owl	inhibition of sporulation|downregulation of sporulation|down regulation of sporulation|down-regulation of sporulation													biological_process											owl:Class	
GO:0042173	biolink:NamedThing	regulation of sporulation resulting in formation of a cellular spore	Any process that modulates the frequency, rate or extent of spore formation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0061103	biolink:NamedThing	carotid body glomus cell differentiation	The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a glomus cell of the carotid body. The carotid body is a specialized chemosensory organ that helps respond to hypoxia.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-04-28T10:59:24Z					biological_process											owl:Class	
GO:0010460	biolink:NamedThing	positive regulation of heart rate	Any process that activates or increases the frequency or rate of heart contraction.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0120270	biolink:NamedThing	regulation of nuclear-transcribed mRNA catabolic process, meiosis-specific transcripts	Any process that modulates the rate, frequency, or extent of selective degradation of meiosis-specific nuclear transcribed transcripts during vegetative growth, by a mechanism that requires determinant of selective removal (DSR) sequences in the targeted mRNAs and involves a YTH family protein.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/18757						krc	2020-10-08T20:52:55Z					biological_process											owl:Class	
GO:0004121	biolink:NamedThing	cystathionine beta-lyase activity	Catalysis of the reaction: cystathionine + H2O = L-homocysteine + NH3 + pyruvate.	tmpzr1t_l9r_go_relaxed.owl	beta-cystathionase activity|cystine lyase activity|L-cystathionine L-homocysteine-lyase (deaminating; pyruvate-forming)|beta C-S lyase activity|L-cystathionine L-homocysteine-lyase (deaminating)|cystathionine L-homocysteine-lyase (deaminating)				EC:4.4.1.8|RHEA:13965|MetaCyc:CYSTATHIONINE-BETA-LYASE-RXN							GO:0008799		molecular_function											owl:Class	
GO:0042139	biolink:NamedThing	early meiotic recombination nodule assembly	During meiosis, the aggregation, arrangement and bonding together of strand exchange proteins (recombinases) to form small, electron dense structures in association with meiotic chromosomes during leptotene and zygotene.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0007146	biolink:NamedThing	meiotic recombination nodule assembly	During meiosis, the aggregation, arrangement and bonding together of strand exchange proteins (recombinases) to form small, electron dense structures in association with meiotic chromosomes.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0045842	biolink:NamedThing	positive regulation of mitotic metaphase/anaphase transition	Any process that activates or increases the frequency, rate or extent of the cell cycle process in which a cell progresses from metaphase to anaphase during mitosis, triggered by the activation of the anaphase promoting complex by Cdc20/Sleepy homolog which results in the degradation of Securin.	tmpzr1t_l9r_go_relaxed.owl	activation of mitotic metaphase/anaphase transition|stimulation of mitotic metaphase/anaphase transition|up regulation of mitotic metaphase/anaphase transition|up-regulation of mitotic metaphase/anaphase transition|upregulation of mitotic metaphase/anaphase transition													biological_process											owl:Class	
GO:0010132	biolink:NamedThing	dhurrin biosynthetic process	The chemical reactions and pathways resulting in the formation of dhurrin, a cyanogenic glucoside which functions as a plant defense compound.	tmpzr1t_l9r_go_relaxed.owl	dhurrin anabolism|dhurrin formation|dhurrin biosynthesis|dhurrin synthesis				MetaCyc:PWY-861									biological_process											owl:Class	
GO:1900311	biolink:NamedThing	positive regulation of maltoheptaose metabolic process	Any process that activates or increases the frequency, rate or extent of maltoheptaose metabolic process.	tmpzr1t_l9r_go_relaxed.owl	upregulation of maltoheptaose metabolism|activation of maltoheptaose metabolic process|up regulation of maltoheptaose metabolism|up regulation of maltoheptaose metabolic process|positive regulation of maltoheptaose metabolism|up-regulation of maltoheptaose metabolism|up-regulation of maltoheptaose metabolic process|upregulation of maltoheptaose metabolic process|activation of maltoheptaose metabolism							tt	2012-04-05T07:59:06Z					biological_process											owl:Class	
GO:0090084	biolink:NamedThing	negative regulation of inclusion body assembly	Any process that decreases the rate, frequency, or extent of inclusion body assembly. Inclusion body assembly is the aggregation, arrangement and bonding together of a set of components to form an inclusion body.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-10-23T11:08:56Z					biological_process											owl:Class	
GO:0030793	biolink:NamedThing	3'-demethylstaurosporine O-methyltransferase activity	Catalysis of the reaction: 3'-demethylstaurosporine + S-adenosyl-L-methionine = S-adenosyl-L-homocysteine + H(+) + staurosporine.	tmpzr1t_l9r_go_relaxed.owl	3'-demethoxy-3'-hydroxystaurosporine O-methyltransferase activity|staurosporine synthase activity|S-adenosyl-L-methionine:3'-demethylstaurosporine O-methyltransferase activity				KEGG_REACTION:R05757|MetaCyc:2.1.1.139-RXN|EC:2.1.1.139|RHEA:11696									molecular_function											owl:Class	
GO:2001068	biolink:NamedThing	arabinoxylan binding	Binding to arabinoxylan.	tmpzr1t_l9r_go_relaxed.owl								jl	2011-09-14T11:58:38Z					molecular_function											owl:Class	
GO:0150176	biolink:NamedThing	positive regulation of phosphatidylethanolamine metabolic process	Any process that activates or increases the frequency, rate or extent of phosphatidylethanolamine metabolic process.	tmpzr1t_l9r_go_relaxed.owl								bc	2020-01-21T14:04:32Z					biological_process											owl:Class	
GO:1903727	biolink:NamedThing	positive regulation of phospholipid metabolic process	Any process that activates or increases the frequency, rate or extent of phospholipid metabolic process.	tmpzr1t_l9r_go_relaxed.owl	activation of phospholipid metabolism|up-regulation of phospholipid metabolic process|up regulation of phospholipid metabolic process|up regulation of phospholipid metabolism|activation of phospholipid metabolic process|upregulation of phospholipid metabolism|positive regulation of phospholipid metabolism|up-regulation of phospholipid metabolism|upregulation of phospholipid metabolic process							sl	2014-12-09T20:49:44Z					biological_process											owl:Class	
GO:0046594	biolink:NamedThing	maintenance of pole plasm mRNA location	The process of maintaining mRNA in a specific location in the oocyte pole plasm. An example of this process is found in Drosophila melanogaster.	tmpzr1t_l9r_go_relaxed.owl	maintenance of pole plasm mRNA localization|maintenance of oocyte pole plasm mRNA localization											GO:0048122		biological_process											owl:Class	
GO:0051237	biolink:NamedThing	maintenance of RNA location	Any process in which RNA is maintained in a location and prevented from moving elsewhere.	tmpzr1t_l9r_go_relaxed.owl	maintenance of RNA localization|RNA retention													biological_process											owl:Class	
GO:0098887	biolink:NamedThing	neurotransmitter receptor transport, endosome to postsynaptic membrane	The directed movement of neurotransmitter receptor from the postsynaptic endosome to the postsynaptic membrane in transport vesicles.	tmpzr1t_l9r_go_relaxed.owl	postsynaptic neurotransmitter receptor endosomal trafficking													biological_process											owl:Class	
GO:0098969	biolink:NamedThing	neurotransmitter receptor transport to postsynaptic membrane	The directed movement of neurotransmitter receptor to the postsynaptic membrane in transport vesicles.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0071800	biolink:NamedThing	podosome assembly	The aggregation, arrangement and bonding together of a set of components to form a podosome, an actin-rich adhesion structure characterized by formation upon cell substrate contact and localization at the substrate-attached part of the cell.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-09-03T11:00:45Z					biological_process											owl:Class	
GO:0010749	biolink:NamedThing	regulation of nitric oxide mediated signal transduction	Any process that modulates the rate, frequency or extent of nitric oxide mediated signal transduction. Nitric oxide mediated signal transduction is a series of molecular signals mediated by the detection of nitric oxide (NO).	tmpzr1t_l9r_go_relaxed.owl	regulation of nitric oxide-mediated signal transduction													biological_process											owl:Class	
GO:0046504	biolink:NamedThing	glycerol ether biosynthetic process	The chemical reactions and pathways resulting in the formation of glycerol ethers, any anhydride formed between two organic hydroxy compounds, one of which is glycerol.	tmpzr1t_l9r_go_relaxed.owl	glycerol ether anabolism|glycerol ether formation|glycerol ether biosynthesis|glycerol ether synthesis													biological_process											owl:Class	
GO:0034971	biolink:NamedThing	histone H3-R17 methylation	The modification of histone H3 by addition of a methyl group to arginine at position 17 of the histone.	tmpzr1t_l9r_go_relaxed.owl	histone lysine H3 R17 methylation|histone H3R17me|histone H3 R17 methylation													biological_process											owl:Class	
GO:1900092	biolink:NamedThing	negative regulation of raffinose biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of raffinose biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of raffinose anabolism|down-regulation of raffinose formation|downregulation of raffinose formation|down regulation of raffinose formation|inhibition of raffinose biosynthetic process|inhibition of raffinose anabolism|inhibition of raffinose biosynthesis|negative regulation of raffinose synthesis|downregulation of raffinose biosynthetic process|down-regulation of raffinose biosynthetic process|down regulation of raffinose anabolism|inhibition of raffinose synthesis|downregulation of raffinose synthesis|down-regulation of raffinose anabolism|down-regulation of raffinose biosynthesis|inhibition of raffinose formation|down regulation of raffinose synthesis|down regulation of raffinose biosynthesis|downregulation of raffinose biosynthesis|downregulation of raffinose anabolism|down regulation of raffinose biosynthetic process|negative regulation of raffinose biosynthesis|negative regulation of raffinose formation|down-regulation of raffinose synthesis							dhl	2012-02-08T06:31:58Z					biological_process											owl:Class	
GO:0071500	biolink:NamedThing	cellular response to nitrosative stress	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrosative stress stimulus. Nitrosative stress is a state often resulting from exposure to high levels of nitric oxide (NO) or the highly reactive oxidant peroxynitrite, which is produced following interaction of NO with superoxide anions.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-12-18T02:49:46Z					biological_process											owl:Class	
GO:0005550	biolink:NamedThing	pheromone binding	Binding to a pheromone, a substance, or characteristic mixture of substances, that is secreted and released by an organism and detected by a second organism of the same or a closely related species, in which it causes a specific reaction, such as a definite behavioral reaction or a developmental process.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0005549	biolink:NamedThing	odorant binding	Binding to an odorant, any substance capable of stimulating the sense of smell.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0071201	biolink:NamedThing	Kv4.3-DPP6 channel complex	A voltage-gated potassium channel complex that contains the peptidase-related protein DPP6 associated with the channel via interaction with the Kv alpha subunit 4.3.	tmpzr1t_l9r_go_relaxed.owl	Kv4.3-DPPX channel complex				CORUM:599			mah	2009-11-23T05:20:54Z					cellular_component											owl:Class	
GO:0033471	biolink:NamedThing	GDP-L-galactose metabolic process	The chemical reactions and pathways involving GDP-L-galactose, a substance composed of L-galactose in glycosidic linkage with guanosine diphosphate.	tmpzr1t_l9r_go_relaxed.owl	GDP-L-galactose metabolism													biological_process											owl:Class	
GO:0002829	biolink:NamedThing	negative regulation of type 2 immune response	Any process that stops, prevents, or reduces the frequency, rate, or extent of a type 2 immune response.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of T-helper 2 type immune response|down-regulation of type 2 immune response|negative regulation of Th2 immune response|inhibition of type 2 immune response|down regulation of type 2 immune response|downregulation of type 2 immune response													biological_process											owl:Class	
GO:0031358	biolink:NamedThing	intrinsic component of chloroplast outer membrane	The component of the chloroplast outer membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.	tmpzr1t_l9r_go_relaxed.owl	intrinsic to chloroplast outer membrane													cellular_component											owl:Class	
GO:0031354	biolink:NamedThing	intrinsic component of plastid outer membrane	The component of the plastid outer membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.	tmpzr1t_l9r_go_relaxed.owl	intrinsic to plastid outer membrane													cellular_component											owl:Class	
GO:0048779	biolink:NamedThing	negative regulation of erythrophore differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of erythrophore differentiation.	tmpzr1t_l9r_go_relaxed.owl	down regulation of erythrophore differentiation|down-regulation of erythrophore differentiation|inhibition of erythrophore differentiation|downregulation of erythrophore differentiation													biological_process											owl:Class	
GO:0050941	biolink:NamedThing	negative regulation of pigment cell differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of pigment cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	downregulation of pigment cell differentiation|down-regulation of pigment cell differentiation|down regulation of pigment cell differentiation|inhibition of pigment cell differentiation													biological_process											owl:Class	
GO:0004965	biolink:NamedThing	G protein-coupled GABA receptor activity	Combining with the amino acid gamma-aminobutyric acid (GABA, 4-aminobutyrate) and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.	tmpzr1t_l9r_go_relaxed.owl	GABA-B receptor activity|G-protein coupled GABA receptor activity|metabotropic GABA receptor				Reactome:R-HSA-1013012|Reactome:R-HSA-1013013									molecular_function											owl:Class	
GO:0006139	biolink:NamedThing	nucleobase-containing compound metabolic process	Any cellular metabolic process involving nucleobases, nucleosides, nucleotides and nucleic acids.	tmpzr1t_l9r_go_relaxed.owl	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process|cellular nucleobase, nucleoside, nucleotide and nucleic acid metabolic process|cellular nucleobase, nucleoside, nucleotide and nucleic acid metabolism|nucleobase, nucleoside, nucleotide and nucleic acid metabolism|nucleobase, nucleoside and nucleotide metabolic process											GO:0055134		biological_process											owl:Class	
GO:0150014	biolink:NamedThing	apical distal dendrite	Any dendrite in a dendritic tree that emerges near the apical pole of a neuron, and which is farthest away from the neuronal cell body (the soma).	tmpzr1t_l9r_go_relaxed.owl								bc	2017-12-21T12:03:28Z					cellular_component											owl:Class	
GO:0097440	biolink:NamedThing	apical dendrite	A dendrite that emerges near the apical pole of a neuron. In bipolar neurons, apical dendrites are located on the opposite side of the soma from the axon.	tmpzr1t_l9r_go_relaxed.owl					NIF_Subcellular:sao273773228			pr	2012-12-06T13:45:18Z					cellular_component											owl:Class	
GO:0008540	biolink:NamedThing	proteasome regulatory particle, base subcomplex	The subcomplex of the proteasome regulatory particle that directly associates with the proteasome core complex.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0018659	biolink:NamedThing	4-hydroxybenzoate 3-monooxygenase activity	Catalysis of the reaction: 4-hydroxybenzoate + NADPH + H+ + O2 = protocatechuate + NADP+ + H2O.	tmpzr1t_l9r_go_relaxed.owl	p-hydroxybenzoic acid hydroxylase activity|p-hydroxybenzoate hydroxylase activity|4-hydroxybenzoate,NADPH:oxygen oxidoreductase (3-hydroxylating)|4-hydroxybenzoate monooxygenase activity|p-hydroxybenzoic acid hydrolase activity|p-hydroxybenzoic hydroxylase activity|para-hydroxybenzoate hydroxylase activity|p-hydroxybenzoate-3-hydroxylase activity|4-hydroxybenzoate 3-hydroxylase activity|p-hydroxybenzoate hydrolyase activity				EC:1.14.13.2|MetaCyc:4-HYDROXYBENZOATE-3-MONOOXYGENASE-RXN|UM-BBD_reactionID:r0109									molecular_function											owl:Class	
GO:0097385	biolink:NamedThing	programmed necrotic cell death in response to starvation	A programmed necrotic cell death occurring as a result of a starvation stimulus (deprivation of nourishment).	tmpzr1t_l9r_go_relaxed.owl	necrotic cell death in response to starvation							pr	2012-10-22T09:02:18Z					biological_process											owl:Class	
GO:2000945	biolink:NamedThing	regulation of amylopectin catabolic process	Any process that modulates the frequency, rate or extent of amylopectin catabolic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of Amylopectin catabolism							tt	2011-08-01T02:15:22Z					biological_process											owl:Class	
GO:0000435	biolink:NamedThing	positive regulation of transcription from RNA polymerase II promoter by galactose	Any process involving galactose that activates or increases the rate of transcription from an RNA polymerase II promoter.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of transcription from RNA polymerase II promoter by galactose|up regulation of transcription from RNA polymerase II promoter by galactose|activation of transcription from RNA polymerase II promoter by galactose|stimulation of transcription from RNA polymerase II promoter by galactose|upregulation of transcription from RNA polymerase II promoter by galactose													biological_process											owl:Class	
GO:0000431	biolink:NamedThing	regulation of transcription from RNA polymerase II promoter by galactose	Any process involving galactose that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0070687	biolink:NamedThing	macropinocytic cup cytoskeleton	The part of the cortical actin cytoskeleton that forms part of a macropinocytic cup.	tmpzr1t_l9r_go_relaxed.owl	crown cytoskeleton							mah	2009-06-03T10:59:50Z					cellular_component											owl:Class	
GO:0071886	biolink:NamedThing	1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine binding	Binding to the amine 1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine, a serotonin receptor agonist that can act as a psychedelic drug.	tmpzr1t_l9r_go_relaxed.owl	1-(4-iodo-2,5-dimethoxyphenyl)-2-aminopropane binding|(+/-)2-(4-iodo-2,5-dimethoxy-phenyl)-1-methyl-ethylamine binding|4-iodo-2,5-dimethoxyphenylisopropylamine binding							mah	2010-09-14T12:29:36Z					molecular_function											owl:Class	
GO:0043176	biolink:NamedThing	amine binding	Binding to an amine, a weakly basic organic compound that contains an amino or a substituted amino group.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0060863	biolink:NamedThing	regulation of floral organ abscission by signal transduction	The cascade of processes by which a signal interacts with a receptor, causing a change in the level or activity of a second messenger or other downstream target, and ultimately modulating the rate, or extent of floral organ abscission.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-08-12T04:07:41Z					biological_process											owl:Class	
GO:0033059	biolink:NamedThing	cellular pigmentation	The deposition or aggregation of coloring matter in a cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0098528	biolink:NamedThing	skeletal muscle fiber differentiation	The process in which a relatively unspecialized cell acquires specialized features of a skeletal muscle fiber cell. Skeletal muscle fiber differentiation starts with myoblast fusion and the appearance of specific cell markers (this is the cell development step). Then individual skeletal muscle fibers fuse to form bigger myotubes and start to contract.	tmpzr1t_l9r_go_relaxed.owl								dos	2013-10-15T14:00:34Z					biological_process											owl:Class	
GO:0035914	biolink:NamedThing	skeletal muscle cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a skeletal muscle cell, a somatic cell located in skeletal muscle.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-06-24T02:36:19Z					biological_process											owl:Class	
GO:0051658	biolink:NamedThing	maintenance of nucleus location	Any process in which the nucleus is maintained in a specific location within a cell and prevented from moving elsewhere.	tmpzr1t_l9r_go_relaxed.owl	maintenance of nucleus localization|maintenance of cell nucleus location													biological_process											owl:Class	
GO:0006287	biolink:NamedThing	base-excision repair, gap-filling	Repair of the damaged strand by the combined action of an apurinic endouclease that degrades a few bases on the damaged strand and a polymerase that synthesizes a 'patch' in the 5' to 3' direction, using the undamaged strand as a template.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1904937	biolink:NamedThing	sensory neuron migration	The orderly movement of a sensory neuron from one site to another.	tmpzr1t_l9r_go_relaxed.owl								ah	2016-02-01T14:15:50Z					biological_process											owl:Class	
GO:1904539	biolink:NamedThing	negative regulation of glycolytic process through fructose-6-phosphate	Any process that stops, prevents or reduces the frequency, rate or extent of glycolytic process through fructose-6-phosphate.	tmpzr1t_l9r_go_relaxed.owl	downregulation of glycolytic process through fructose-6-phosphate|downregulation of glycolysis through fructose-6-phosphate|negative regulation of glycolysis through fructose-6-phosphate|down regulation of glycolysis through fructose-6-phosphate|down-regulation of glycolysis through fructose-6-phosphate|inhibition of glycolysis through fructose-6-phosphate|down regulation of glycolytic process through fructose-6-phosphate|down-regulation of glycolytic process through fructose-6-phosphate|inhibition of glycolytic process through fructose-6-phosphate							dph	2015-08-07T11:35:16Z					biological_process											owl:Class	
GO:2000629	biolink:NamedThing	negative regulation of miRNA metabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of miRNA metabolic process.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of microRNA metabolic process							dph	2011-04-18T03:47:58Z					biological_process											owl:Class	
GO:0042587	biolink:NamedThing	glycogen granule	Cytoplasmic bead-like structures of animal cells, visible by electron microscope. Each granule is a functional unit with the biosynthesis and catabolism of glycogen being catalyzed by enzymes bound to the granule surface.	tmpzr1t_l9r_go_relaxed.owl	glycogen particle				NIF_Subcellular:sao1081228141									cellular_component											owl:Class	
GO:0019749	biolink:NamedThing	cytoskeleton-dependent cytoplasmic transport, nurse cell to oocyte	The directed movement of substances along cytoskeletal elements, such as microfilaments or microtubules, from a nurse cell to an oocyte.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0032741	biolink:NamedThing	positive regulation of interleukin-18 production	Any process that activates or increases the frequency, rate, or extent of interleukin-18 production.	tmpzr1t_l9r_go_relaxed.owl	upregulation of interleukin-18 production|positive regulation of interleukin-18 biosynthetic process|stimulation of interleukin-18 production|positive regulation of interleukin-18 secretion|up regulation of interleukin-18 production|positive regulation of IL-18 production|up-regulation of interleukin-18 production|activation of interleukin-18 production											GO:0150122|GO:0045383		biological_process											owl:Class	
GO:0045328	biolink:NamedThing	cytochrome P450 4A1-heme linkage	The covalent linkage of heme to cytochrome P450 4A1 via hydroxyheme-L-glutamyl ester.	tmpzr1t_l9r_go_relaxed.owl	cytochrome P450 4A1-haem linkage				RESID:AA0324									biological_process											owl:Class	
GO:0046069	biolink:NamedThing	cGMP catabolic process	The chemical reactions and pathways resulting in the breakdown of cyclic GMP, guanosine 3',5'-phosphate.	tmpzr1t_l9r_go_relaxed.owl	cGMP breakdown|cGMP degradation|cGMP catabolism													biological_process											owl:Class	
GO:0046338	biolink:NamedThing	phosphatidylethanolamine catabolic process	The chemical reactions and pathways resulting in the breakdown of phosphatidylethanolamine, any of a class of glycerophospholipids in which a phosphatidyl group is esterified to the hydroxyl group of ethanolamine.	tmpzr1t_l9r_go_relaxed.owl	phosphatidylethanolamine catabolism|phosphatidylethanolamine degradation|phosphatidylethanolamine breakdown													biological_process											owl:Class	
GO:0016586	biolink:NamedThing	RSC-type complex	A SWI/SNF-type complex that contains a bromodomain containing-protein, such as yeast Rsc1 or Rsc4 or mammalian PB1/BAF180. The RSC complex is generally recruited to RNA polymerase III promoters and is specifically recruited to RNA polymerase II promoters by transcriptional activators and repressors; it is also involved in non-homologous end joining.	tmpzr1t_l9r_go_relaxed.owl	Polybromo- and BAF containing complex|PBAF complex|SWI/SNF complex B	https://github.com/geneontology/go-ontology/issues/14106						mah	2009-04-29T01:07:26Z			GO:0070604		cellular_component											owl:Class	
GO:1905861	biolink:NamedThing	intranuclear rod assembly	The aggregation, arrangement and bonding together of a set of components to form an intranuclear rod.	tmpzr1t_l9r_go_relaxed.owl	intranuclear actin rod formation|intranuclear actin rod assembly|intranuclear rod formation							dph	2017-01-23T17:59:27Z					biological_process											owl:Class	
GO:0042150	biolink:NamedThing	plasmid recombination	A process of DNA recombination occurring within a plasmid or between plasmids and other plasmids or DNA molecules.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0060518	biolink:NamedThing	cell migration involved in prostatic bud elongation	The orderly movement of epithelial cells from one site to another contributing to the elongation of the primary prostatic bud.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1990733	biolink:NamedThing	titin-telethonin complex	A protein complex formed between the N-terminus of the giant sarcomeric filament protein titin and the Z-disk ligand, telethonin. The complex is part of the Z-disk of the skeletal and cardiac sarcomere. Telethonin binding to titin might be essential for the initial assembly, stabilization and functional integrity of the titin filament, and hence important for muscle contraction relaxation in mature myofibrils.	tmpzr1t_l9r_go_relaxed.owl	Titin-Tcap complex					An example of this are TTN and TCAP in human (UniProt symbols Q8WZ42 and O15273 respectively) in PMID:16407954 (inferred from direct assay).		ame	2015-04-24T14:57:08Z					cellular_component											owl:Class	
GO:0020023	biolink:NamedThing	kinetoplast	A sub-structure within the large single mitochondrion of kinetoplastid parasites and which is closely associated with the flagellar pocket and basal body of the flagellum.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Kinetoplast									cellular_component											owl:Class	
GO:0043494	biolink:NamedThing	CLRC complex	An cullin-dependent E3 ubiquitin ligase/histone H3-K9 methyltransferase complex essential for heterochromatin assembly by RNAi.	tmpzr1t_l9r_go_relaxed.owl	Rik1-E3 ubiquitin ligase complex|CLRC ubiquitin ligase complex|Rik1 E3 ubiquitin ligase complex|Clr4-Rik1-Cul4 complex													cellular_component											owl:Class	
GO:0070104	biolink:NamedThing	negative regulation of interleukin-6-mediated signaling pathway	Any process that decreases the rate, frequency or extent of the series of molecular events generated as a consequence of interleukin-6 binding to a cell surface receptor.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of IL-6-mediated signaling pathway|negative regulation of interleukin-6-mediated signalling pathway													biological_process											owl:Class	
GO:0045876	biolink:NamedThing	positive regulation of sister chromatid cohesion	Any process that activates or increases the frequency, rate or extent of sister chromatid cohesion.	tmpzr1t_l9r_go_relaxed.owl	up regulation of sister chromatid cohesion|upregulation of sister chromatid cohesion|up-regulation of sister chromatid cohesion|stimulation of sister chromatid cohesion|activation of sister chromatid cohesion													biological_process											owl:Class	
GO:0019811	biolink:NamedThing	cocaine binding	Binding to cocaine (2-beta-carbomethoxy-3-beta-benzoxytropane), an alkaloid obtained from dried leaves of the South American shrub Erythroxylon coca or by chemical synthesis.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0046335	biolink:NamedThing	ethanolamine biosynthetic process	The chemical reactions and pathways resulting in the formation of ethanolamine (2-aminoethanol), an important water-soluble base of phospholipid (phosphatidylethanolamine).	tmpzr1t_l9r_go_relaxed.owl	ethanolamine anabolism|ethanolamine formation|ethanolamine biosynthesis|ethanolamine synthesis													biological_process											owl:Class	
GO:0106108	biolink:NamedThing	negative regulation of (R)-mevalonic acid biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of (R)-mevalonic acid biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl								hjd	2018-03-27T14:15:55Z					biological_process											owl:Class	
GO:0042040	biolink:NamedThing	metal incorporation into metallo-molybdopterin complex	The incorporation of a metal into a metallo-molybdopterin complex.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0010913	biolink:NamedThing	regulation of sterigmatocystin biosynthetic process	Any process that modulates the rate, frequency, or extent of sterigmatocystin biosynthesis. Sterigmatocystin biosynthetic processes are the chemical reactions and pathways resulting in the formation of sterigmatocystin, a carcinogenic mycotoxin produced in high yields by strains of the common molds.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0002523	biolink:NamedThing	leukocyte migration involved in inflammatory response	The movement of a leukocyte within or between different tissues and organs of the body contributing to an inflammatory response.	tmpzr1t_l9r_go_relaxed.owl	leukocyte migration during inflammatory response|leucocyte trafficking during inflammatory response|leukocyte trafficking during inflammatory response|immune cell trafficking during inflammatory response|immune cell migration during inflammatory response|leucocyte migration during inflammatory response													biological_process											owl:Class	
GO:1902125	biolink:NamedThing	(+)-pinoresinol catabolic process	The chemical reactions and pathways resulting in the breakdown of (+)-pinoresinol.	tmpzr1t_l9r_go_relaxed.owl	(+)-pinoresinol breakdown|(+)-pinoresinol catabolism|(+)-pinoresinol degradation							ms	2013-05-21T08:49:23Z					biological_process											owl:Class	
GO:0060618	biolink:NamedThing	nipple development	The progression of the nipple over time, from its formation to the mature structure. The nipple is a part of the mammary gland that protrudes from the surface ectoderm.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-05-18T09:29:38Z					biological_process											owl:Class	
GO:0060909	biolink:NamedThing	regulation of DNA replication initiation involved in plasmid copy number maintenance	Any process that modulates the frequency, rate or extent of initiation of plasmid DNA replication that contributes to copy number maintenance.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-09-04T02:51:48Z					biological_process											owl:Class	
GO:1904654	biolink:NamedThing	negative regulation of lung alveolus development	Any process that stops, prevents or reduces the frequency, rate or extent of lung alveolus development.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of alveolarization|down regulation of alveolarization|inhibition of alveologenesis|down-regulation of alveologenesis|down regulation of alveologenesis|downregulation of alveologenesis|down regulation of lung alveolus development|downregulation of alveolarization|negative regulation of alveolarization|down-regulation of lung alveolus development|inhibition of lung alveolus development|negative regulation of alveologenesis|inhibition of alveolarization|downregulation of lung alveolus development							sl	2015-09-03T22:44:50Z					biological_process											owl:Class	
GO:1904653	biolink:NamedThing	regulation of lung alveolus development	Any process that modulates the frequency, rate or extent of lung alveolus development.	tmpzr1t_l9r_go_relaxed.owl	regulation of alveologenesis|regulation of alveolarization							sl	2015-09-03T22:44:44Z					biological_process											owl:Class	
GO:0071464	biolink:NamedThing	cellular response to hydrostatic pressure	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrostatic pressure stimulus. Hydrostatic pressure is the force acting on an object in a system where the fluid is at rest (as opposed to moving). The weight of the fluid above the object creates pressure on it.	tmpzr1t_l9r_go_relaxed.owl	cellular response to static fluid pressure|cellular response to biomechanical stress							mah	2009-12-18T11:34:07Z					biological_process											owl:Class	
GO:0001898	biolink:NamedThing	regulation of cytolysis by symbiont of host cells	Any process in which an organism modulates the frequency, rate or extent of the cytolysis by that organism of cells in its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	regulation by symbiont of cytolysis of host cells													biological_process											owl:Class	
GO:0015306	biolink:NamedThing	sialate:cation symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sialate(out) + cation(out) = sialate(in) + cation(in).	tmpzr1t_l9r_go_relaxed.owl	cation:sialate symporter activity|cation/sialate symporter activity|sialate/cation symporter activity|sialate transporter activity													molecular_function											owl:Class	
GO:1903805	biolink:NamedThing	L-valine import across plasma membrane	The directed movement of L-valine from outside of a cell, across the plasma membrane and into the cytosol.	tmpzr1t_l9r_go_relaxed.owl	valine import|L-valine import into cell							tb	2012-09-24T14:28:58Z			GO:0090468		biological_process											owl:Class	
GO:0045822	biolink:NamedThing	negative regulation of heart contraction	Any process that stops, prevents, or reduces the frequency, rate or extent of heart contraction.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of cardiac contraction|downregulation of heart contraction|down-regulation of heart contraction|inhibition of heart contraction|down regulation of heart contraction													biological_process											owl:Class	
GO:0061296	biolink:NamedThing	negative regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis	Any process that reduces the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the mesonephros.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of mesenchymal stem cell apoptotic process involved in mesonephric nephron morphogenesis|negative regulation of mesenchymal stem cell apoptosis involved in mesonephric nephron morphogenesis							dph	2010-09-06T09:54:49Z					biological_process											owl:Class	
GO:0060803	biolink:NamedThing	BMP signaling pathway involved in mesodermal cell fate specification	A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, which contributes to a cell becoming specified to adopt a mesodermal fate.	tmpzr1t_l9r_go_relaxed.owl	BMP signalling pathway involved in mesodermal cell fate specification							dph	2009-08-06T01:47:39Z					biological_process											owl:Class	
GO:0018553	biolink:NamedThing	3-(2,3-dihydroxyphenyl)propionate 1,2-dioxygenase activity	Catalysis of the reaction: 3-(2,3-dihydroxyphenyl)propionate + O2 = 2-hydroxy-6-keto-nona-2,4-dienedioate.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_enzymeID:e0309									molecular_function											owl:Class	
GO:0038192	biolink:NamedThing	gastric inhibitory peptide signaling pathway	The series of molecular signals generated as a consequence of a gastric inhibitory peptide (GIP) binding to a cell surface receptor. The pathway proceeds with the receptor transmitting the signal to a heterotrimeric G-protein complex and ends with regulation of a downstream cellular process, e.g. transcription.	tmpzr1t_l9r_go_relaxed.owl	glucose-dependent insulinotropic polypeptide signaling|gastric inhibitory polypeptide receptor signaling pathway|GIP signaling							bf	2013-09-02T15:57:49Z					biological_process											owl:Class	
GO:0032648	biolink:NamedThing	regulation of interferon-beta production	Any process that modulates the frequency, rate, or extent of interferon-beta production.	tmpzr1t_l9r_go_relaxed.owl	regulation of IFN-beta production|regulation of interferon-beta biosynthetic process|regulation of interferon-beta secretion											GO:0035547|GO:0045357		biological_process											owl:Class	
GO:1901981	biolink:NamedThing	phosphatidylinositol phosphate binding	Binding to phosphatidylinositol phosphate.	tmpzr1t_l9r_go_relaxed.owl								tb	2013-03-12T18:21:22Z					molecular_function											owl:Class	
GO:0035091	biolink:NamedThing	phosphatidylinositol binding	Binding to an inositol-containing glycerophospholipid, i.e. phosphatidylinositol (PtdIns) and its phosphorylated derivatives.	tmpzr1t_l9r_go_relaxed.owl	phosphoinositide binding													molecular_function											owl:Class	
GO:0010872	biolink:NamedThing	regulation of cholesterol esterification	Any process that modulates the frequency, rate or extent of cholesterol esterification. Cholesterol esterification is the lipid modification process in which a sterol ester is formed by the combination of a carboxylic acid (often a fatty acid) and cholesterol. In the blood this process is associated with the conversion of free cholesterol into cholesteryl ester, which is then sequestered into the core of a lipoprotein particle.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0019500	biolink:NamedThing	cyanide catabolic process	The chemical reactions and pathways resulting in the breakdown of cyanide, NC-, the anion of hydrocyanic acid. Cyanide is a potent inhibitor of respiration.	tmpzr1t_l9r_go_relaxed.owl	cyanide degradation|cyanide breakdown|cyanide catabolism				MetaCyc:P401-PWY									biological_process											owl:Class	
GO:0019499	biolink:NamedThing	cyanide metabolic process	The chemical reactions and pathways involving cyanide, NC-, the anion of hydrocyanic acid. Cyanide is a potent inhibitor of respiration, reacting with the ferric form of cytochrome aa3 and thus blocking the electron transport chain.	tmpzr1t_l9r_go_relaxed.owl	cyanide metabolism													biological_process											owl:Class	
GO:0071561	biolink:NamedThing	nucleus-vacuole junction	An organelle membrane contact site formed between the vacuole membrane and the outer nuclear membrane. In S. cerevisiae these contacts are mediated through direct physical interaction between Vac8p and Nvj1p.	tmpzr1t_l9r_go_relaxed.owl	NV junction|nucleus-vacuole membrane contact site|NVJ							mah	2010-01-20T02:09:42Z					cellular_component											owl:Class	
GO:0009300	biolink:NamedThing	antisense RNA transcription	The synthesis of antisense RNA, an RNA molecule complementary in sequence to another RNA or DNA molecule, which, by binding the latter, acts to inhibit its function and/or completion of synthesis, on a template of DNA.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0018154	biolink:NamedThing	peptide cross-linking via (2R,6R)-lanthionine	The formation of a protein-protein cross-link between peptidyl-serine and peptidyl-cysteine by the synthesis of (2R,6R)-lanthionine (L-lanthionine).	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0110									biological_process											owl:Class	
GO:0098538	biolink:NamedThing	lumenal side of transport vesicle membrane	The side (leaflet) of the transport vesicle membrane that faces the lumen.	tmpzr1t_l9r_go_relaxed.owl	internal side of transport vesicle membrane							dos	2013-10-24T11:43:55Z					cellular_component											owl:Class	
GO:0008875	biolink:NamedThing	gluconate dehydrogenase activity	Catalysis of the reaction: D-gluconate + NADP+ = dehydro-D-gluconate + NADPH + H+.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0004459	biolink:NamedThing	L-lactate dehydrogenase activity	Catalysis of the reaction: (S)-lactate + NAD+ = pyruvate + NADH + H+.	tmpzr1t_l9r_go_relaxed.owl	L-lactic dehydrogenase activity|L-lactic acid dehydrogenase activity				EC:1.1.1.27|Reactome:R-HSA-6807826|Reactome:R-HSA-70510|RHEA:23444|Reactome:R-HSA-71849|MetaCyc:L-LACTATE-DEHYDROGENASE-RXN									molecular_function											owl:Class	
GO:0010947	biolink:NamedThing	negative regulation of meiotic joint molecule formation	Any process that decreases the frequency, rate or extent of meiotic joint molecule formation. Meiotic joint molecule formation is the conversion of the paired broken DNA and homologous duplex DNA into a four-stranded branched intermediate, known as a joint molecule, formed during meiotic recombination.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-04-27T09:48:53Z					biological_process											owl:Class	
GO:0047498	biolink:NamedThing	calcium-dependent phospholipase A2 activity	Catalysis of the reaction: phosphatidylcholine + H2O = 1-acylglycerophosphocholine + a carboxylate. This reaction requires Ca2+.	tmpzr1t_l9r_go_relaxed.owl	calcium-dependent cytosolic phospholipase A2 activity|calcium-dependent secreted phospholipase A2 activity				Reactome:R-HSA-111883									molecular_function											owl:Class	
GO:0016597	biolink:NamedThing	amino acid binding	Binding to an amino acid, organic acids containing one or more amino substituents.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0060457	biolink:NamedThing	negative regulation of digestive system process	Any process that decreases the frequency, rate or extent of a digestive system process, a physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0043722	biolink:NamedThing	4-hydroxyphenylacetate decarboxylase activity	Catalysis of the reaction: (4-hydroxyphenyl)acetate + H(+) = 4-cresol + CO(2).	tmpzr1t_l9r_go_relaxed.owl	4-(hydroxyphenyl)acetate carboxy-lyase (4-methylphenol-forming)|p-Hpd activity|p-hydroxyphenylacetate decarboxylase activity|4-Hpd activity|4-hydroxyphenylacetate carboxy-lyase activity				EC:4.1.1.83|RHEA:22732|MetaCyc:4.1.1.83-RXN|KEGG_REACTION:R07312									molecular_function											owl:Class	
GO:0004616	biolink:NamedThing	phosphogluconate dehydrogenase (decarboxylating) activity	Catalysis of the reaction: 6-phospho-D-gluconate + NADP+ = D-ribulose 5-phosphate + CO2 + NADPH + H+.	tmpzr1t_l9r_go_relaxed.owl	6-phospho-D-gluconate dehydrogenase activity|6-phosphogluconic dehydrogenase activity|6-phospho-D-gluconate:NADP+ 2-oxidoreductase (decarboxylating)|phosphogluconic acid dehydrogenase activity|6-phosphogluconate dehydrogenase (decarboxylating)|6PGD activity|6-phosphogluconic carboxylase activity				EC:1.1.1.44|MetaCyc:6PGLUCONDEHYDROG-RXN|Reactome:R-HSA-71299|RHEA:10116									molecular_function											owl:Class	
GO:0019826	biolink:NamedThing	oxygen sensor activity	Binding to and responding, e.g. by conformational change, to changes in the cellular level of oxygen (O2).	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0019825	biolink:NamedThing	oxygen binding	Binding to oxygen (O2).	tmpzr1t_l9r_go_relaxed.owl	cytochrome P450 activity|cytochrome P450													molecular_function											owl:Class	
GO:0102710	biolink:NamedThing	D-inositol-3-phosphate glycosyltransferase activity	Catalysis of the reaction: UDP-N-acetyl-alpha-D-glucosamine + 1D-myo-inositol 3-phosphate = 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside 3-phosphate + UDP + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-6501|RHEA:26188|EC:2.4.1.250									molecular_function											owl:Class	
GO:0043794	biolink:NamedThing	formate dehydrogenase (coenzyme F420) activity	Catalysis of the reaction: formate + coenzyme F420 = CO2 + reduced coenzyme F420.	tmpzr1t_l9r_go_relaxed.owl	formate dehydrogenase (F420) activity				EC:1.2.99.-									molecular_function											owl:Class	
GO:0001561	biolink:NamedThing	fatty acid alpha-oxidation	A metabolic pathway by which 3-methyl branched fatty acids are degraded. These compounds are not degraded by the normal peroxisomal beta-oxidation pathway, because the 3-methyl blocks the dehydrogenation of the hydroxyl group by hydroxyacyl-CoA dehydrogenase. The 3-methyl branched fatty acid is converted in several steps to pristenic acid, which can then feed into the beta-oxidative pathway.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:PWY-2501									biological_process											owl:Class	
GO:0019395	biolink:NamedThing	fatty acid oxidation	The removal of one or more electrons from a fatty acid, with or without the concomitant removal of a proton or protons, by reaction with an electron-accepting substance, by addition of oxygen or by removal of hydrogen.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:FAO-PWY									biological_process											owl:Class	
GO:0036039	biolink:NamedThing	curcumin metabolic process	The chemical reactions and pathways involving the polyphenol, curcumin.	tmpzr1t_l9r_go_relaxed.owl	turmeric yellow metabolic process|(1E,6E)-1,7-bis(4-hydroxy-3-methoxyphenyl)hepta-1,6-diene-3,5-dione metabolic process|turmeric yellow metabolism|diferuloylmethane metabolism|(1E,6E)-1,7-bis(4-hydroxy-3-methoxyphenyl)hepta-1,6-diene-3,5-dione metabolism|curcumin metabolism|diferuloylmethane metabolic process							bf	2011-11-22T01:58:57Z					biological_process											owl:Class	
GO:0047425	biolink:NamedThing	1-pyrroline-4-hydroxy-2-carboxylate deaminase activity	Catalysis of the reaction: 4-hydroxy-1-pyrroline-2-carboxylate + H(2)O + H(+) = 2,5-dioxopentanoate + NH(4)(+).	tmpzr1t_l9r_go_relaxed.owl	1-pyrroline-4-hydroxy-2-carboxylate aminohydrolase (decyclizing)|HPC deaminase activity				KEGG_REACTION:R02280|MetaCyc:3.5.4.22-RXN|EC:3.5.4.22|RHEA:10560									molecular_function											owl:Class	
GO:1900281	biolink:NamedThing	positive regulation of CD4-positive, alpha-beta T cell costimulation	Any process that activates or increases the frequency, rate or extent of CD4-positive, alpha-beta T cell costimulation.	tmpzr1t_l9r_go_relaxed.owl	upregulation of CD4-positive, alpha beta T cell costimulation|up-regulation of CD4-positive, alpha beta T cell costimulation|activation of CD4-positive, alpha beta T cell costimulation|positive regulation of CD4-positive, alpha beta T cell costimulation|up regulation of CD4-positive, alpha beta T cell costimulation							rl	2012-04-04T08:56:45Z					biological_process											owl:Class	
GO:0008869	biolink:NamedThing	galactonate dehydratase activity	Catalysis of the reaction: D-galactonate = 2-dehydro-3-deoxy-D-galactonate + H(2)O.	tmpzr1t_l9r_go_relaxed.owl	D-galactonate hydro-lyase (2-dehydro-3-deoxy-D-galactonate-forming)|D-galactonate hydro-lyase activity|D-galactonate dehydrase activity|D-galactonate dehydratase activity				KEGG_REACTION:R03033|RHEA:18649|EC:4.2.1.6|MetaCyc:GALACTONDEHYDRAT-RXN									molecular_function											owl:Class	
GO:0008190	biolink:NamedThing	eukaryotic initiation factor 4E binding	Binding to eukaryotic initiation factor 4E, a polypeptide factor involved in the initiation of ribosome-mediated translation.	tmpzr1t_l9r_go_relaxed.owl	eIF4E binding													molecular_function											owl:Class	
GO:0035425	biolink:NamedThing	autocrine signaling	Signaling between cells of the same type. The signal produced by the signaling cell binds to a receptor on, and affects a cell of the same type.	tmpzr1t_l9r_go_relaxed.owl	autocrine signalling							bf	2010-03-29T02:15:52Z					biological_process											owl:Class	
GO:0050482	biolink:NamedThing	arachidonic acid secretion	The controlled release of arachidonic acid from a cell or a tissue.	tmpzr1t_l9r_go_relaxed.owl						This term should be used to annotate release of arachidonic acid from the cell. For the hydrolytic release of arachidonic acid from a phospholipid, consider instead annotating to 'phospholipase A2 activity ; GO:0004623'.								biological_process											owl:Class	
GO:1903963	biolink:NamedThing	arachidonate transport	The directed movement of an arachidonate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	arachidonic acid transport							bhm	2015-02-25T16:06:14Z					biological_process											owl:Class	
GO:0043281	biolink:NamedThing	regulation of cysteine-type endopeptidase activity involved in apoptotic process	Any process that modulates the activity of a cysteine-type endopeptidase involved in apoptosis.	tmpzr1t_l9r_go_relaxed.owl	regulation of caspase activity|regulation of caspase activation											GO:0043026		biological_process											owl:Class	
GO:0002772	biolink:NamedThing	inhibitory C-type lectin receptor signaling pathway	A series of molecular signals initiated by the binding of an extracellular ligand to an inhibitory C-type lectin receptor capable of inhibiting an immune effector process contributing to an immune response.	tmpzr1t_l9r_go_relaxed.owl	inhibitory C-type lectin receptor signalling pathway|Ly49 inhibitory receptor signaling pathway													biological_process											owl:Class	
GO:0030666	biolink:NamedThing	endocytic vesicle membrane	The lipid bilayer surrounding an endocytic vesicle.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0030128	biolink:NamedThing	clathrin coat of endocytic vesicle	A clathrin coat found on an endocytic vesicle.	tmpzr1t_l9r_go_relaxed.owl	clathrin coat of endocytotic vesicle													cellular_component											owl:Class	
GO:0006784	biolink:NamedThing	heme A biosynthetic process	The chemical reactions and pathways resulting in the formation of heme A, a derivative of heme found in cytochrome aa3.	tmpzr1t_l9r_go_relaxed.owl	heme A anabolism|heme A formation|heme A biosynthesis|haem A biosynthesis|heme A synthesis|haem A biosynthetic process													biological_process											owl:Class	
GO:2000295	biolink:NamedThing	regulation of hydrogen peroxide catabolic process	Any process that modulates the frequency, rate or extent of hydrogen peroxide catabolic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of hydrogen peroxide degradation|regulation of H2O2 catabolic process|regulation of H2O2 scavenging|regulation of hydrogen peroxide scavenging|regulation of hydrogen peroxide catabolism|regulation of detoxification of H2O2|regulation of hydrogen peroxide breakdown|regulation of hydrogen peroxide removal|regulation of detoxification of hydrogen peroxide							rl	2010-12-21T03:30:51Z					biological_process											owl:Class	
GO:0009560	biolink:NamedThing	embryo sac egg cell differentiation	The process in which an uncellularized embryo sac nucleus cellularizes and acquires the specialized features of an egg cell. An example of this process is found in Arabidopsis thaliana.	tmpzr1t_l9r_go_relaxed.owl	female gametophyte egg cell differentiation|female gamete generation											GO:0048233		biological_process											owl:Class	
GO:0070417	biolink:NamedThing	cellular response to cold	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that organism.	tmpzr1t_l9r_go_relaxed.owl	cellular response to cold stress													biological_process											owl:Class	
GO:0009409	biolink:NamedThing	response to cold	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that organism.	tmpzr1t_l9r_go_relaxed.owl	freezing tolerance													biological_process											owl:Class	
GO:1902916	biolink:NamedThing	positive regulation of protein polyubiquitination	Any process that activates or increases the frequency, rate or extent of protein polyubiquitination.	tmpzr1t_l9r_go_relaxed.owl	upregulation of protein polyubiquitylation|activation of protein polyubiquitylation|activation of protein polyubiquitinylation|up regulation of protein polyubiquitinylation|upregulation of protein polyubiquitinylation|positive regulation of polyubiquitin|upregulation of polyubiquitin|activation of protein polyubiquitination|up-regulation of protein polyubiquitylation|up regulation of protein polyubiquitylation|positive regulation of protein polyubiquitinylation|up-regulation of protein polyubiquitination|positive regulation of protein polyubiquitylation|up regulation of protein polyubiquitination|activation of polyubiquitin|up-regulation of protein polyubiquitinylation|upregulation of protein polyubiquitination|up regulation of polyubiquitin|up-regulation of polyubiquitin							di	2014-04-18T22:10:04Z					biological_process											owl:Class	
GO:0004940	biolink:NamedThing	beta1-adrenergic receptor activity	Combining with epinephrine or norepinephrine to initiate a change in cell activity via activation of a G protein, with pharmacological characteristics of beta1-adrenergic receptors.	tmpzr1t_l9r_go_relaxed.owl	beta1 adrenoceptor													molecular_function											owl:Class	
GO:0042622	biolink:NamedThing	photoreceptor outer segment membrane	The membrane surrounding the outer segment of a vertebrate photoreceptor.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0033640	biolink:NamedThing	modulation by symbiont of host response to osmotic stress	Any process in which an organism modulates a change in state or activity of a host cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0070208	biolink:NamedThing	protein heterotrimerization	The formation of a protein heterotrimer, a macromolecular structure consisting of three noncovalently associated subunits, of which not all are identical.	tmpzr1t_l9r_go_relaxed.owl	protein heterotrimer formation|protein heterotrimer biosynthetic process|protein heterotrimer assembly|protein heterotrimer biosynthesis													biological_process											owl:Class	
GO:1901413	biolink:NamedThing	regulation of tetrapyrrole biosynthetic process from glycine and succinyl-CoA	Any process that modulates the frequency, rate or extent of tetrapyrrole biosynthetic process from glycine and succinyl-CoA.	tmpzr1t_l9r_go_relaxed.owl	regulation of tetrapyrrole anabolism from glycine and succinyl-CoA|regulation of tetrapyrrole biosynthesis from glycine and succinyl-CoA|regulation of tetrapyrrole formation from glycine and succinyl-CoA|regulation of tetrapyrrole synthesis from glycine and succinyl-CoA							tt	2012-10-01T16:27:43Z					biological_process											owl:Class	
GO:1900542	biolink:NamedThing	regulation of purine nucleotide metabolic process	Any process that modulates the frequency, rate or extent of purine nucleotide metabolic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of purine metabolism|regulation of purine metabolic process|regulation of purine nucleotide metabolism							krc	2012-05-11T05:43:15Z					biological_process											owl:Class	
GO:0097052	biolink:NamedThing	L-kynurenine metabolic process	The chemical reactions and pathways involving L-kynurenine, the L-enantiomer of the amino acid kynurenine (3-(2-aminobenzoyl)-alanine).	tmpzr1t_l9r_go_relaxed.owl	L-kynurenine metabolism							pr	2011-05-24T03:28:44Z					biological_process											owl:Class	
GO:0009384	biolink:NamedThing	N-acylmannosamine kinase activity	Catalysis of the reaction: ATP + N-acyl-D-mannosamine = ADP + N-acyl-D-mannosamine 6-phosphate.	tmpzr1t_l9r_go_relaxed.owl	N-acetylmannosamine kinase activity|N-acyl-D-mannosamine kinase activity|acetylmannosamine kinase activity|ATP:N-acyl-D-mannosamine 6-phosphotransferase activity|acylaminodeoxymannokinase activity|acylmannosamine kinase activity|ATP:N-acetylmannosamine 6-phosphotransferase activity|acetylamidodeoxymannokinase activity|acylmannosamine kinase (phosphorylating)				RHEA:23832|MetaCyc:N-ACYLMANNOSAMINE-KINASE-RXN|Reactome:R-HSA-4088322|Reactome:R-HSA-4085028|EC:2.7.1.60									molecular_function											owl:Class	
GO:0044577	biolink:NamedThing	xylose catabolic process to ethanol	The anaerobic chemical reactions and pathways resulting in the breakdown of xylose, an aldopentose, where one of the resulting products is ethanol.	tmpzr1t_l9r_go_relaxed.owl	xylose catabolism to ethanol							jl	2012-04-19T03:50:46Z					biological_process											owl:Class	
GO:0042843	biolink:NamedThing	D-xylose catabolic process	The chemical reactions and pathways resulting in the breakdown of D-xylose, a naturally occurring plant polysaccharide.	tmpzr1t_l9r_go_relaxed.owl	D-xylose catabolism|D-xylose degradation|D-xylose breakdown													biological_process											owl:Class	
GO:1902829	biolink:NamedThing	regulation of spinal cord association neuron differentiation	Any process that modulates the frequency, rate or extent of spinal cord association neuron differentiation.	tmpzr1t_l9r_go_relaxed.owl	regulation of spinal cord dorsal interneuron differentiation							mr	2014-03-31T17:10:55Z					biological_process											owl:Class	
GO:0051272	biolink:NamedThing	positive regulation of cellular component movement	Any process that activates or increases the frequency, rate or extent of the movement of a cellular component.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of cellular component motion													biological_process											owl:Class	
GO:1901903	biolink:NamedThing	tyrocidine catabolic process	The chemical reactions and pathways resulting in the breakdown of tyrocidine.	tmpzr1t_l9r_go_relaxed.owl	tyrocidine catabolism|tyrocidine breakdown|tyrocidine degradation							yaf	2013-02-12T23:40:34Z					biological_process											owl:Class	
GO:0045036	biolink:NamedThing	protein targeting to chloroplast	The process of directing proteins towards the chloroplast, usually using signals contained within the protein. Imported proteins are synthesized as cytosolic precursors containing N-terminal uptake-targeting sequences that direct each protein to its correct subcompartment and are subsequently cleaved.	tmpzr1t_l9r_go_relaxed.owl	protein-chloroplast targeting													biological_process											owl:Class	
GO:1902252	biolink:NamedThing	positive regulation of erythrocyte apoptotic process	Any process that activates or increases the frequency, rate or extent of erythrocyte apoptotic process.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of red blood cell apoptosis|upregulation of red blood cell apoptosis|up regulation of erythrocyte apoptosis|up-regulation of RBC apoptosis|up regulation of RBC apoptotic process|activation of erythrocyte apoptotic process|upregulation of erythrocyte apoptosis|positive regulation of RBC apoptotic process|positive regulation of erythrocyte apoptosis|up regulation of red blood cell apoptosis|up-regulation of red blood cell apoptosis|activation of RBC apoptosis|up regulation of RBC apoptosis|up regulation of red blood cell apoptotic process|up-regulation of erythrocyte apoptotic process|activation of RBC apoptotic process|positive regulation of red blood cell apoptotic process|positive regulation of RBC apoptosis|upregulation of RBC apoptotic process|upregulation of erythrocyte apoptotic process|activation of red blood cell apoptotic process|up-regulation of erythrocyte apoptosis|activation of erythrocyte apoptosis|up regulation of erythrocyte apoptotic process|upregulation of red blood cell apoptotic process|up-regulation of red blood cell apoptotic process|upregulation of RBC apoptosis|activation of red blood cell apoptosis|up-regulation of RBC apoptotic process							rl	2013-06-20T19:31:04Z					biological_process											owl:Class	
GO:0070921	biolink:NamedThing	regulation of production of siRNA involved in gene silencing by small RNA	Any process that modulates the frequency, rate or extent of the production of siRNA, the cleavage of double-stranded RNA to form small interfering RNA molecules (siRNAs) of 21-23 nucleotides, in the context of gene silencing by small RNA.	tmpzr1t_l9r_go_relaxed.owl	regulation of production of siRNA involved in chromatin silencing by small RNA|regulation of chromatin silencing by small RNA, production of siRNA	https://github.com/geneontology/go-ontology/issues/22058						mah	2009-09-11T03:42:51Z					biological_process											owl:Class	
GO:0047995	biolink:NamedThing	hydroxyphenylpyruvate reductase activity	Catalysis of the reaction: 3-(4-hydroxyphenyl)lactate + NAD+ = 3-(4-hydroxyphenyl)pyruvate + NADH.	tmpzr1t_l9r_go_relaxed.owl	4-hydroxyphenyllactate:NAD+ oxidoreductase activity|HPRP				MetaCyc:HYDROXYPHENYLPYRUVATE-REDUCTASE-RXN|RHEA:10780|EC:1.1.1.237									molecular_function											owl:Class	
GO:0010368	biolink:NamedThing	chloroplast isoamylase complex	A protein complex whose composition varies amongst species; in rice it probably exists in a homo-tetramer to homo-hexamer form and in Gram negative bacteria as a dimer. Functions in the hydrolysis of alpha-(1,6)-D-glucosidic branch linkages. Isoamylases in plants are intracellular and probably chloroplast localized.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0043033	biolink:NamedThing	isoamylase complex	A protein complex whose composition varies amongst species; in rice it probably exists in a homo-tetramer to homo-hexamer form and in Gram-negative bacteria as a dimer. Functions in the hydrolysis of alpha-(1,6)-D-glucosidic branch linkages.	tmpzr1t_l9r_go_relaxed.owl	debranching enzyme complex													cellular_component											owl:Class	
GO:0090630	biolink:NamedThing	activation of GTPase activity	Any process that initiates the activity of an inactive GTPase through the replacement of GDP by GTP.	tmpzr1t_l9r_go_relaxed.owl	activation of Ran GTPase activity|Rap GTPase activation|Ran GTPase activation|activation of ARF GTPase activity|Cdc42 GTPase activation|Ras GTPase activation|activation of Ras GTPase activity|activation of Rap GTPase activity|Rho GTPase activation|Ral GTPase activation|activation of Ral GTPase activity|activation of Rac GTPase activity|activation of Rab GTPase activity|activation of Rho GTPase activity|Rac GTPase activation|activation of Cdc42 GTPase activity|ARF GTPase activation|Rab GTPase activation							tb	2015-02-11T16:09:19Z			GO:0032857|GO:0032858|GO:0032864|GO:0032863|GO:0032860|GO:0032859|GO:0032861|GO:0032856|GO:0032862		biological_process											owl:Class	
GO:0031943	biolink:NamedThing	regulation of glucocorticoid metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving glucocorticoids.	tmpzr1t_l9r_go_relaxed.owl	regulation of glucocorticoid metabolism													biological_process											owl:Class	
GO:0047066	biolink:NamedThing	phospholipid-hydroperoxide glutathione peroxidase activity	Catalysis of the reaction: a lipid hydroperoxide + 2 reduced glutathione = 2 H2O + lipid + 2 oxidized glutathione.	tmpzr1t_l9r_go_relaxed.owl	glutathione:lipid-hydroperoxide oxidoreductase activity|peroxidation-inhibiting protein activity|peroxidation-inhibiting protein: peroxidase, glutathione (phospholipid hydroperoxide-reducing)|hydroperoxide glutathione peroxidase activity|PHGPX|phospholipid hydroperoxide glutathione peroxidase activity				Reactome:R-HSA-9020273|Reactome:R-HSA-9018895|Reactome:R-HSA-9018868|MetaCyc:1.11.1.12-RXN|EC:1.11.1.12|RHEA:19057|Reactome:R-HSA-9020271									molecular_function											owl:Class	
GO:0048079	biolink:NamedThing	regulation of cuticle pigmentation	Any process that modulates the frequency, rate or extent of establishment of a pattern of pigment in the cuticle of an organism.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1990968	biolink:NamedThing	modulation by host of RNA binding by virus	A process in which a host organism modulates the frequency, rate or extent of a viral gene product binding to RNA.	tmpzr1t_l9r_go_relaxed.owl	modulation by host of viral protein:RNA interaction					Note that the bound RNA may originate from the virus or another organism, including the host.		bf	2016-06-21T11:56:10Z					biological_process											owl:Class	
GO:0034928	biolink:NamedThing	1-hydroxypyrene 6,7-monooxygenase activity	Catalysis of the reaction: 1-hydroxypyrene + O2 + 2 H+ + 2 e- = 1-hydroxypyrene-6,7-oxide + H2O.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0946									molecular_function											owl:Class	
GO:0070370	biolink:NamedThing	cellular heat acclimation	Any process that increases heat tolerance of a cell in response to high temperatures.	tmpzr1t_l9r_go_relaxed.owl	cellular thermotolerance													biological_process											owl:Class	
GO:0010286	biolink:NamedThing	heat acclimation	Any process that increases heat tolerance of an organism in response to high temperatures.	tmpzr1t_l9r_go_relaxed.owl	thermotolerance													biological_process											owl:Class	
GO:0102738	biolink:NamedThing	(gibberellin-14), 2-oxoglutarate:oxygen oxidoreductase activity	Catalysis of the reaction: gibberellin A14 + O2 + 2-oxoglutarate <=> gibberellin A37 + carbon dioxide + succinate.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-7589									molecular_function											owl:Class	
GO:0050066	biolink:NamedThing	lysine 2,3-aminomutase activity	Catalysis of the reaction: L-lysine = (3S)-3,6-diaminohexanoate.	tmpzr1t_l9r_go_relaxed.owl	L-lysine 2,3-aminomutase activity				RHEA:19177|MetaCyc:LYSINE-23-AMINOMUTASE-RXN|EC:5.4.3.2|KEGG_REACTION:R00461									molecular_function											owl:Class	
GO:0099162	biolink:NamedThing	regulation of neurotransmitter loading into synaptic vesicle	Any process that modulates the frequency, rate or extent of neurotransmitter loading into synaptic vesicles.	tmpzr1t_l9r_go_relaxed.owl	regulation of neurotransmitter uptake into synaptic vesicle|regulation of synaptic vesicle neurotransmitter loading							dos	2017-09-10T11:07:57Z					biological_process											owl:Class	
GO:1902883	biolink:NamedThing	negative regulation of response to oxidative stress	Any process that stops, prevents or reduces the frequency, rate or extent of response to oxidative stress.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of response to oxidative stress|inhibition of response to oxidative stress|downregulation of response to oxidative stress|down regulation of response to oxidative stress							kmv	2014-04-03T20:30:20Z					biological_process											owl:Class	
GO:0015565	biolink:NamedThing	threonine efflux transmembrane transporter activity	Enables the transfer of threonine from the inside of the cell to the outside of the cell across a membrane.	tmpzr1t_l9r_go_relaxed.owl	threonine export transporter activity|threonine efflux permease activity|threonine export protein													molecular_function											owl:Class	
GO:0034639	biolink:NamedThing	L-amino acid efflux transmembrane transporter activity	Enables the transfer of an L-amino acid from the inside of the cell to the outside of the cell across a membrane.	tmpzr1t_l9r_go_relaxed.owl	L-amino acid export transporter activity|L-amino acid efflux permease activity													molecular_function											owl:Class	
GO:0051423	biolink:NamedThing	positive regulation of endo-1,4-beta-xylanase activity	Any process that activates or increases the frequency, rate or extent of endo-(1->4)-beta-xylanase activity, the catalysis of the endohydrolysis of (1->4)-beta-D-xylosidic linkages in xylans.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of endo-1,4-beta-xylanase activity|activation of endo-1,4-beta-xylanase activity|endo-1,4-beta-xylanase activator|up regulation of endo-1,4-beta-xylanase activity|upregulation of endo-1,4-beta-xylanase activity|stimulation of endo-1,4-beta-xylanase activity|xylanase activator													biological_process											owl:Class	
GO:0075296	biolink:NamedThing	positive regulation of ascospore formation	Any process that activates, maintains or increases the frequency, rate or extent of ascospore formation, a process in which a sexual spore, named ascospore, from Ascomycete fungi was produced inside an ascus.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0046587	biolink:NamedThing	positive regulation of calcium-dependent cell-cell adhesion	Any process that activates or increases the frequency, rate or extent of calcium-dependent cell-cell adhesion.	tmpzr1t_l9r_go_relaxed.owl	stimulation of calcium-dependent cell-cell adhesion|upregulation of calcium-dependent cell-cell adhesion|activation of calcium-dependent cell-cell adhesion|up regulation of calcium-dependent cell-cell adhesion|up-regulation of calcium-dependent cell-cell adhesion													biological_process											owl:Class	
GO:0044566	biolink:NamedThing	chondrocyte activation	A change in the morphology or behavior of a chondrocyte resulting from exposure to an activating factor such as a cellular or soluble ligand. A chondrocyte is a polymorphic cell that forms cartilage.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-04-05T04:45:38Z					biological_process											owl:Class	
GO:0071444	biolink:NamedThing	cellular response to pheromone	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pheromone stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular pheromone response							mah	2009-12-16T04:05:33Z					biological_process											owl:Class	
GO:0060453	biolink:NamedThing	regulation of gastric acid secretion	Any process that modulates the rate frequency or extent of gastric secretion. Gastric secretion is the regulated release of gastric acid (hydrochloric acid) by parietal or oxyntic cells during digestion.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0046573	biolink:NamedThing	lactonohydrolase activity	Catalysis of the hydrolysis of lactone rings (intramolecular cyclic esters) to produce a hydroxyl group and a carboxyl group.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1905848	biolink:NamedThing	positive regulation of cellular response to oxidopamine	Any process that activates or increases the frequency, rate or extent of cellular response to oxidopamine.	tmpzr1t_l9r_go_relaxed.owl	upregulation of cellular response to oxidopamine|activation of cellular response to oxidopamine|up regulation of cellular response to oxidopamine|up-regulation of cellular response to oxidopamine							rz	2017-01-19T10:47:04Z					biological_process											owl:Class	
GO:0046059	biolink:NamedThing	dAMP catabolic process	The chemical reactions and pathways resulting in the breakdown of dAMP, deoxyadenosine monophosphate (2'-deoxyadenosine 5'-phosphate).	tmpzr1t_l9r_go_relaxed.owl	dAMP breakdown|dAMP catabolism|dAMP degradation													biological_process											owl:Class	
GO:0075521	biolink:NamedThing	microtubule-dependent intracellular transport of viral material towards nucleus	The directed movement of a virus, or part of a virus, towards the host cell nucleus using host microtubules.	tmpzr1t_l9r_go_relaxed.owl	microtubule-dependent intracellular transport of viral material to nucleus				VZ:983			jl	2011-08-03T02:09:21Z					biological_process											owl:Class	
GO:0075606	biolink:NamedThing	transport of viral material towards nucleus	The directed movement of a virus, or part of a virus, towards the host cell nucleus. The process begins after viral entry, and ends when the viral material is at the nuclear membrane.	tmpzr1t_l9r_go_relaxed.owl	cytoplasmic inwards viral transport|viral genome transport to host cell nucleus|transport of viral material to nucleus				VZ:990	This process does not include the viral material crossing the nuclear membrane. For transport of viral material into the nucleus, consider instead: 'viral penetration into host nucleus ; GO:0075732'.		jl	2009-11-05T03:33:36Z					biological_process											owl:Class	
GO:0033807	biolink:NamedThing	icosanoyl-CoA synthase activity	Catalysis of the reaction: stearoyl-CoA + malonyl-CoA + 2 NAD(P)H + 2 H+ = icosanoyl-CoA + CO2 + 2 NAD(P)+.	tmpzr1t_l9r_go_relaxed.owl	C18-CoA elongase activity|stearoyl-CoA:malonyl-CoA C-acyltransferase (decarboxylating, oxoacyl- and enoyl-reducing) activity|stearoyl-CoA elongase activity|acyl-CoA elongase activity				MetaCyc:ICOSANOYL-COA-SYNTHASE-RXN|EC:2.3.1.119									molecular_function											owl:Class	
GO:0015649	biolink:NamedThing	2-keto-3-deoxygluconate:proton symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: 2-keto-3-deoxygluconate(out) + H+(out) = 2-keto-3-deoxygluconate(in) + H+(in).	tmpzr1t_l9r_go_relaxed.owl	2-keto-3-deoxygluconate:hydrogen symporter activity													molecular_function											owl:Class	
GO:0015355	biolink:NamedThing	secondary active monocarboxylate transmembrane transporter activity	Catalysis of the movement of a monocarboxylate, any compound containing a single carboxyl group (COOH or COO-), by uniport, symport or antiport across a membrane by a carrier-mediated mechanism.	tmpzr1t_l9r_go_relaxed.owl	monocarboxylate porter activity													molecular_function											owl:Class	
GO:0072581	biolink:NamedThing	protein-N6-(L-lysyl)-L-lysine modification to protein-N6-(beta-lysyl)-L-lysine	The modification of an N6-(lysyl)-L-lysine residue in a protein, producing protein-N6-(beta-lysyl)-L-lysine ((2S)-2-amino-6-([(2S)-2,6-diaminohexanoyl]amino)hexanoic acid). This modification is observed in, and is probably unique to, translation elongation factor P (EF-P).	tmpzr1t_l9r_go_relaxed.owl								mah	2011-02-07T11:51:02Z					biological_process											owl:Class	
GO:0065004	biolink:NamedThing	protein-DNA complex assembly	The aggregation, arrangement and bonding together of proteins and DNA molecules to form a protein-DNA complex.	tmpzr1t_l9r_go_relaxed.owl	DNA-protein complex assembly													biological_process											owl:Class	
GO:0046140	biolink:NamedThing	corrin biosynthetic process	The chemical reactions and pathways resulting in the formation of corrin, C19H22N4, the fundamental heterocyclic skeleton of the corrinoids. It consists of four reduced pyrrole rings joined into a macrocyclic ring. Corrin is the core of the vitamin B12 molecule.	tmpzr1t_l9r_go_relaxed.owl	corrin biosynthesis|corrin anabolism|corrin synthesis|corrin formation													biological_process											owl:Class	
GO:0061087	biolink:NamedThing	positive regulation of histone H3-K27 methylation	Any process that increases the rate, frequency, or extent of histone H3-K27 methylation. Histone H3-K27 methylation is the modification of histone H3 by addition of a methyl group to lysine at position 27 of the histone.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-04-26T01:23:52Z					biological_process											owl:Class	
GO:0071192	biolink:NamedThing	Kv4.2-KChIP1 channel complex	A voltage-gated potassium channel complex that contains the Kv channel interacting protein KChIP1 associated with the channel via interaction with the Kv alpha subunit 4.2.	tmpzr1t_l9r_go_relaxed.owl					CORUM:606			mah	2009-11-23T04:51:42Z					cellular_component											owl:Class	
GO:0044727	biolink:NamedThing	DNA demethylation of male pronucleus	The active DNA demethylation of the paternal genome that takes place before the first cell division.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-10-24T14:25:35Z					biological_process											owl:Class	
GO:0052677	biolink:NamedThing	D-arabinitol dehydrogenase, D-xylulose forming (NADP+) activity	Catalysis of the reaction: D-arabinitol + NADP+ = D-xylulose + NADPH + H+.	tmpzr1t_l9r_go_relaxed.owl	NADP+-dependent D-arabinitol dehydrogenase activity|D-arabinitol:NADP+ dehydrogenase activity|D-arabinitol dehydrogenase 1 activity|ARD1p				KEGG_REACTION:R07143|MetaCyc:RXN-7971|RHEA:21276			ai	2011-04-12T02:33:43Z					molecular_function											owl:Class	
GO:1903235	biolink:NamedThing	positive regulation of calcium ion-dependent exocytosis of neurotransmitter	Any process that activates or increases the frequency, rate or extent of calcium ion-dependent exocytosis of neurotransmitter.	tmpzr1t_l9r_go_relaxed.owl	activation of calcium ion-dependent exocytosis of neurotransmitter|up-regulation of calcium ion-dependent exocytosis of neurotransmitter|upregulation of calcium ion-dependent exocytosis of neurotransmitter|up regulation of calcium ion-dependent exocytosis of neurotransmitter					An example of this is Rab3gap1 in mouse (Q80UJ7) in PMID:16782817 (IMP)		pad	2014-07-31T11:54:46Z					biological_process											owl:Class	
GO:0106017	biolink:NamedThing	phosphatidylinositol-3,4-bisphosphate phosphatase activity	Catalysis of the reaction: 1-phosphatidyl-myo-inositol 3,4-bisphosphate + H2O = 1-phosphatidyl-1D-myo-inositol phosphate + phosphate.	tmpzr1t_l9r_go_relaxed.owl								hjd	2017-05-10T14:08:06Z					molecular_function											owl:Class	
GO:1990267	biolink:NamedThing	response to transition metal nanoparticle	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a transition metal nanoparticle.	tmpzr1t_l9r_go_relaxed.owl	response to neutral metal atoms|response to colloidal metal							sl	2014-01-10T17:16:41Z					biological_process											owl:Class	
GO:0015175	biolink:NamedThing	neutral amino acid transmembrane transporter activity	Enables the transfer of neutral amino acids from one side of a membrane to the other. Neutral amino acids have side chains with no charge at pH 7.3.	tmpzr1t_l9r_go_relaxed.owl	neutral amino acid transporter activity													molecular_function											owl:Class	
GO:0015314	biolink:NamedThing	aminotriazole:proton antiporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + aminotriazole(in) = H+(in) + aminotriazole(out).	tmpzr1t_l9r_go_relaxed.owl	aminotriazole:hydrogen antiporter activity													molecular_function											owl:Class	
GO:1901478	biolink:NamedThing	aminotriazole transmembrane transporter activity	Enables the transfer of amitrole from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	aminotriazole transporter activity							tb	2012-10-04T23:21:06Z			GO:0015241		molecular_function											owl:Class	
GO:0046316	biolink:NamedThing	gluconokinase activity	Catalysis of the reaction: D-gluconate + ATP = 6-phospho-D-gluconate + ADP + 2 H(+).	tmpzr1t_l9r_go_relaxed.owl	ATP:D-gluconate 6-phosphotransferase activity|gluconokinase (phosphorylating)|gluconate kinase activity				EC:2.7.1.12|KEGG_REACTION:R01737|RHEA:19433|MetaCyc:GLUCONOKIN-RXN									molecular_function											owl:Class	
GO:1904562	biolink:NamedThing	phosphatidylinositol 5-phosphate metabolic process	The chemical reactions and pathways involving phosphatidylinositol 5-phosphate.	tmpzr1t_l9r_go_relaxed.owl	phosphatidylinositol 5-phosphate metabolism							dph	2015-08-18T16:21:44Z					biological_process											owl:Class	
GO:0046141	biolink:NamedThing	corrin catabolic process	The chemical reactions and pathways resulting in the breakdown of corrin, C19H22N4, the fundamental heterocyclic skeleton of the corrinoids. It consists of four reduced pyrrole rings joined into a macrocyclic ring. Corrin is the core of the vitamin B12 molecule.	tmpzr1t_l9r_go_relaxed.owl	corrin degradation|corrin breakdown|corrin catabolism													biological_process											owl:Class	
GO:0031435	biolink:NamedThing	mitogen-activated protein kinase kinase kinase binding	Binding to a mitogen-activated protein kinase kinase kinase, a protein that can phosphorylate a MAP kinase kinase.	tmpzr1t_l9r_go_relaxed.owl	MAPKKK binding													molecular_function											owl:Class	
GO:1901038	biolink:NamedThing	cyanidin 3-O-glucoside metabolic process	The chemical reactions and pathways involving cyanidin 3-O-beta-D-glucoside.	tmpzr1t_l9r_go_relaxed.owl	cyanidin 3-O-beta-D-glucoside metabolic process|cyanidin 3-O-beta-D-glucoside metabolism							tb	2012-06-22T12:16:26Z					biological_process											owl:Class	
GO:0010489	biolink:NamedThing	UDP-4-keto-6-deoxy-glucose-3,5-epimerase activity	Catalysis of the reaction: UDP-4-keto-6-deoxyglucose = UDP-4-keto-rhamnose.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0047077	biolink:NamedThing	Photinus-luciferin 4-monooxygenase (ATP-hydrolyzing) activity	Catalysis of the reaction: O2 + ATP + Photinus luciferin = light + diphosphate + AMP + CO2 + oxidized Photinus luciferin.	tmpzr1t_l9r_go_relaxed.owl	Photinus-luciferin 4-monooxygenase (ATP-hydrolysing)|firefly luciferin luciferase activity|Photinus pyralis luciferase activity|Photinus-luciferin:oxygen 4-oxidoreductase (decarboxylating, ATP-hydrolysing)|luciferase (firefly luciferin)|luciferase activity|Photinus luciferin 4-monooxygenase (adenosine triphosphate-hydrolyzing)|firefly luciferase activity				EC:1.13.12.7|MetaCyc:1.13.12.7-RXN|RHEA:10732									molecular_function											owl:Class	
GO:0046760	biolink:NamedThing	viral budding from Golgi membrane	A viral budding that starts with formation of a membrane curvature in the host Golgi membrane.	tmpzr1t_l9r_go_relaxed.owl	viral budding from Golgi membrane by viral capsid envelopment|Golgi membrane viral budding during viral capsid envelopment|virus budding from Golgi membrane|viral budding from Golgi membrane during viral capsid envelopment|virus budding from Golgi membrane during viral capsid envelopment|Golgi membrane viral budding|virus budding from Golgi membrane by viral capsid envelopment											GO:0046750|GO:0046763		biological_process											owl:Class	
GO:0046605	biolink:NamedThing	regulation of centrosome cycle	Any process that modulates the frequency, rate or extent of the centrosome cycle, the processes of centrosome duplication and separation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0035814	biolink:NamedThing	negative regulation of renal sodium excretion	Any process that decreases the amount of sodium excreted in urine over a unit of time.	tmpzr1t_l9r_go_relaxed.owl						The amount of sodium excreted in urine over a unit of time can be decreased by decreasing the volume of urine produced (antidiuresis) and/or by decreasing the concentration of sodium in the urine.		bf	2011-04-20T01:27:39Z					biological_process											owl:Class	
GO:1904666	biolink:NamedThing	regulation of ubiquitin protein ligase activity	Any process that modulates the frequency, rate or extent of ubiquitin protein ligase activity.	tmpzr1t_l9r_go_relaxed.owl	regulation of protein ubiquitination activity|regulation of E3|regulation of APC-fizzy related complex activity|regulation of ubiquitin ligase activity							dph	2015-09-08T15:26:59Z			GO:1903834		biological_process											owl:Class	
GO:0051438	biolink:NamedThing	regulation of ubiquitin-protein transferase activity	Any process that modulates the frequency, rate or extent of ubiquitin transferase activity.	tmpzr1t_l9r_go_relaxed.owl	anaphase-promoting complex regulator|SCF complex regulator|ubiquitin-protein transferase regulator|regulation of ubiquitin transferase activity|APC regulator|ubiquitin transferase regulator													biological_process											owl:Class	
GO:0018191	biolink:NamedThing	peptidyl-serine octanoylation	The octanoylation of peptidyl-serine to form peptidyl-O3-octanoyl-L-serine, typical of the protein ghrelin.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0290									biological_process											owl:Class	
GO:0050544	biolink:NamedThing	arachidonic acid binding	Binding to arachidonic acid, a straight chain fatty acid with 20 carbon atoms and four double bonds per molecule. Arachidonic acid is the all-Z-(5,8,11,14)-isomer.	tmpzr1t_l9r_go_relaxed.owl	arachidonate binding													molecular_function											owl:Class	
GO:0050543	biolink:NamedThing	icosatetraenoic acid binding	Binding to icosatetraenoic acid, any straight-chain fatty acid with twenty carbon atoms and four double bonds per molecule.	tmpzr1t_l9r_go_relaxed.owl	eicosatetraenoic acid binding													molecular_function											owl:Class	
GO:0005601	biolink:NamedThing	classical-complement-pathway C3/C5 convertase complex	A heterodimeric protein complex that catalyzes the cleavage of complement components C3 and C5, and acts in the classical pathway of complement activation; consists of one monomer of C2a and one monomer of C4b; C2a is the catalytic subunit, but cannot catalyze cleavage alone.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:1902386	biolink:NamedThing	glycyrrhetinate biosynthetic process	The chemical reactions and pathways resulting in the formation of glycyrrhetinate.	tmpzr1t_l9r_go_relaxed.owl	glycyrrhetinate anabolism|glycyrrhetinate synthesis|glycyrrhetinate biosynthesis|glycyrrhetinate formation							ms	2013-09-03T12:56:19Z					biological_process											owl:Class	
GO:0018195	biolink:NamedThing	peptidyl-arginine modification	The modification of peptidyl-arginine.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0034310	biolink:NamedThing	primary alcohol catabolic process	The chemical reactions and pathways resulting in the breakdown of primary alcohols. A primary alcohol is any alcohol in which a hydroxy group, -OH, is attached to a saturated carbon atom which has either three hydrogen atoms attached to it or only one other carbon atom and two hydrogen atoms attached to it.	tmpzr1t_l9r_go_relaxed.owl	primary alcohol breakdown|monohydric alcohol catabolic process|primary alcohol catabolism|primary alcohol degradation													biological_process											owl:Class	
GO:0070198	biolink:NamedThing	protein localization to chromosome, telomeric region	Any process in which a protein is transported to, or maintained at, the telomeric region of a chromosome.	tmpzr1t_l9r_go_relaxed.owl	protein localization to telomere|protein localisation to chromosome, telomeric region													biological_process											owl:Class	
GO:0034502	biolink:NamedThing	protein localization to chromosome	Any process in which a protein is transported to, or maintained at, a specific location on a chromosome.	tmpzr1t_l9r_go_relaxed.owl	condensin localization to chromosome|protein localisation to chromosome													biological_process											owl:Class	
GO:0099160	biolink:NamedThing	postsynaptic intermediate filament cytoskeleton	The intermediate filament cytoskeleton that is part of a postsynapse.	tmpzr1t_l9r_go_relaxed.owl								dos	2017-08-28T15:26:08Z					cellular_component											owl:Class	
GO:0009678	biolink:NamedThing	pyrophosphate hydrolysis-driven proton transmembrane transporter activity	Enables the transmembrane transport of one proton (H+), driven by the hydrolysis of pyrophosphate, and generating a proton motive force.	tmpzr1t_l9r_go_relaxed.owl	proton-pumping pyrophosphatase|diphosphate hydrolysis-driven proton transmembrane transporter activity|proton-pumping diphosphatase|PP(i) hydrolysis-driven proton transmembrane transporter activity|hydrogen-translocating pyrophosphatase activity|proton-translocating pyrophosphatase activity|H(+)-exporting diphosphatase				RHEA:13973|EC:7.1.3.1|TC:3.A.10|MetaCyc:TRANS-RXN-370									molecular_function											owl:Class	
GO:0047342	biolink:NamedThing	galactose-1-phosphate thymidylyltransferase activity	Catalysis of the reaction: alpha-D-galactose 1-phosphate + dTTP = diphosphate + dTDP-D-galactose.	tmpzr1t_l9r_go_relaxed.owl	dTDP galactose pyrophosphorylase activity|dTDP-galactose diphosphorylase activity|thymidine diphosphogalactose pyrophosphorylase activity|dTDP-galactose pyrophosphorylase activity|dTTP:alpha-D-galactose-1-phosphate thymidylyltransferase activity|thymidine triphosphate:alpha-D-galactose 1-phosphate thymidylyltransferase activity|galactose 1-phosphate thymidylyl transferase activity				MetaCyc:2.7.7.32-RXN|EC:2.7.7.32|RHEA:17165|KEGG_REACTION:R02329									molecular_function											owl:Class	
GO:0140320	biolink:NamedThing	PAMP receptor decoy activity	A gene product which recognizes, binds and sequesters PAMP ligands in order to prevent them from binding and activating to the host PAMP receptor. Usually this activity is encoded by a symbiont or a pathogen to prevent activation of the host innate immune response.	tmpzr1t_l9r_go_relaxed.owl	pathogen-associated molecular pattern receptor decoy activity|pattern recognition receptor decoy activity							pg	2019-04-02T11:07:13Z					molecular_function											owl:Class	
GO:0050339	biolink:NamedThing	thymidine-triphosphatase activity	Catalysis of the reaction: dTTP + H2O = dTDP + phosphate.	tmpzr1t_l9r_go_relaxed.owl	thymidine triphosphate nucleotidohydrolase activity|deoxythymidine-5'-triphosphatase activity|dTTP nucleotidohydrolase activity|dTTPase activity				RHEA:19013|EC:3.6.1.39|MetaCyc:THYMIDINE-TRIPHOSPHATASE-RXN									molecular_function											owl:Class	
GO:0017111	biolink:NamedThing	nucleoside-triphosphatase activity	Catalysis of the reaction: a nucleoside triphosphate + H2O = nucleoside diphosphate + phosphate.	tmpzr1t_l9r_go_relaxed.owl	nucleoside triphosphate hydrolase activity|NTPase activity|unspecific diphosphate phosphohydrolase activity|nucleoside 5-triphosphatase activity|nucleoside triphosphate phosphohydrolase activity|apyrase activity|nucleoside triphosphatase activity|nucleoside-5-triphosphate phosphohydrolase activity				Reactome:R-HSA-8851110|MetaCyc:NUCLEOSIDE-TRIPHOSPHATASE-RXN|Reactome:R-HSA-8851089|RHEA:23680|Reactome:R-HSA-8851494|Reactome:R-HSA-8850846|Reactome:R-HSA-8851234|Reactome:R-HSA-8851538									molecular_function											owl:Class	
GO:0060740	biolink:NamedThing	prostate gland epithelium morphogenesis	The process in which the anatomical structures of epithelia of the prostate gland are generated and organized. An epithelium consists of closely packed cells arranged in one or more layers, that covers the outer surfaces of the body or lines any internal cavity or tube.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-06-16T09:23:22Z					biological_process											owl:Class	
GO:0034950	biolink:NamedThing	phenylboronic acid monooxygenase activity	Catalysis of the reaction: phenylboronic acid + O2 + 2 H+ + 2 e- = phenol + B(OH)3.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r1020									molecular_function											owl:Class	
GO:0097311	biolink:NamedThing	bacterial biofilm matrix	A structure lying external to bacterial cells. A biofilm is an aggregate of surface-associated bacteria, and the biofilm matrix is the envelope of polymeric substances that surrounds the bacteria.	tmpzr1t_l9r_go_relaxed.owl								pr	2012-05-24T11:20:50Z					cellular_component											owl:Class	
GO:0062039	biolink:NamedThing	biofilm matrix	A structure lying external to microbial cells. A biofilm is an aggregate of surface-associated cells, and the biofilm matrix is the envelope of polymeric substances that surrounds the cells.	tmpzr1t_l9r_go_relaxed.owl								dph	2018-05-04T12:49:17Z					cellular_component											owl:Class	
GO:1903846	biolink:NamedThing	positive regulation of cellular response to transforming growth factor beta stimulus	Any process that activates or increases the frequency, rate or extent of cellular response to transforming growth factor beta stimulus.	tmpzr1t_l9r_go_relaxed.owl	upregulation of cellular response to transforming growth factor beta stimulus|activation of cellular response to TGF-beta stimulus|up-regulation of cellular response to transforming growth factor beta stimulus|activation of cellular response to TGFbeta stimulus|up regulation of cellular response to transforming growth factor beta stimulus|activation of cellular response to transforming growth factor beta stimulus|up regulation of cellular response to TGF-beta stimulus|upregulation of cellular response to TGF-beta stimulus|up regulation of cellular response to TGFbeta stimulus|positive regulation of cellular response to TGF-beta stimulus|positive regulation of cellular response to TGFbeta stimulus|up-regulation of cellular response to TGF-beta stimulus|upregulation of cellular response to TGFbeta stimulus|up-regulation of cellular response to TGFbeta stimulus							rph	2015-01-23T11:25:30Z					biological_process											owl:Class	
GO:0002550	biolink:NamedThing	positive regulation of plasma kallikrein-kinin cascade	Any process that activates or increases the frequency, rate, or extent of the plasma kallikrein-kinin cascade.	tmpzr1t_l9r_go_relaxed.owl	up regulation of plasma kallikrein-kinin cascade|stimulation of plasma kallikrein-kinin cascade|up-regulation of plasma kallikrein-kinin cascade|activation of plasma kallikrein-kinin cascade|upregulation of plasma kallikrein-kinin cascade													biological_process											owl:Class	
GO:1905708	biolink:NamedThing	regulation of cell morphogenesis involved in conjugation with cellular fusion	Any process that modulates the location, frequency, rate or extent of cell morphogenesis involved in conjugation with cellular fusion.	tmpzr1t_l9r_go_relaxed.owl	regulation of shmoo orientation|regulation of shmooing							mah	2016-11-18T11:33:54Z					biological_process											owl:Class	
GO:0042652	biolink:NamedThing	mitochondrial respiratory chain complex I, peripheral segment	The peripheral segment of respiratory chain complex I located in the mitochondrion. Respiratory chain complex I is an enzyme of the respiratory chain, consisting of at least 34 polypeptide chains. The electrons of NADH enter the chain at this complex. The complete complex is L-shaped, with a horizontal arm lying in the membrane and a vertical arm that projects into the matrix.	tmpzr1t_l9r_go_relaxed.owl	NADH dehydrogenase (ubiquinone) complex, peripheral segment|NADH-Q oxidoreductase complex, peripheral segment													cellular_component											owl:Class	
GO:0061851	biolink:NamedThing	leading edge of lamellipodium	That part of the lamellipodium which represents the distal part of the structure.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:1903024	biolink:NamedThing	positive regulation of ascospore-type prospore membrane formation	Any process that activates or increases the frequency, rate or extent of formation of an ascospore-type prospore membrane.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of ascospore-type prospore membrane assembly|up regulation of FSM biosynthesis|up-regulation of FSM formation|positive regulation of forespore membrane biosynthesis|activation of ascospore-type prospore membrane assembly|positive regulation of FSM assembly|activation of FSM formation|up regulation of ascospore-type prospore membrane assembly|activation of forespore membrane biosynthesis|upregulation of FSM biosynthesis|positive regulation of FSM biosynthesis|up-regulation of FSM assembly|upregulation of ascospore-type prospore membrane assembly|activation of forespore membrane formation|upregulation of forespore membrane formation|up-regulation of FSM biosynthesis|up-regulation of forespore membrane biosynthesis|upregulation of forespore membrane biosynthesis|up regulation of FSM assembly|positive regulation of forespore membrane formation|activation of FSM assembly|activation of FSM biosynthesis|up regulation of forespore membrane formation|up regulation of forespore membrane biosynthesis|upregulation of FSM formation|positive regulation of ascospore-type prospore membrane assembly|up-regulation of forespore membrane formation|positive regulation of FSM formation|upregulation of FSM assembly|up regulation of FSM formation							al	2014-05-15T08:51:58Z					biological_process											owl:Class	
GO:0019370	biolink:NamedThing	leukotriene biosynthetic process	The chemical reactions and pathways resulting in the formation of leukotriene, a pharmacologically active substance derived from a polyunsaturated fatty acid, such as arachidonic acid.	tmpzr1t_l9r_go_relaxed.owl	leukotriene synthesis|leukotriene biosynthesis|leukotriene anabolism|leukotriene formation				Wikipedia:Leukotriene#Leukotriene_synthesis									biological_process											owl:Class	
GO:0046518	biolink:NamedThing	octamethylcyclotetrasiloxane metabolic process	The chemical reactions and pathways involving octamethylcyclotetrasiloxane, a cyclic silicone-oxygen ring compound with two methyl groups attached to each silicone atom.	tmpzr1t_l9r_go_relaxed.owl	octamethylcyclotetrasiloxane metabolism													biological_process											owl:Class	
GO:0034061	biolink:NamedThing	DNA polymerase activity	Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1); the synthesis of DNA from deoxyribonucleotide triphosphates in the presence of a nucleic acid template and a 3'hydroxyl group.	tmpzr1t_l9r_go_relaxed.owl	deoxyribonucleate nucleotidyltransferase activity|deoxyribonucleic acid polymerase activity|DNA nucleotidyltransferase activity|deoxyribonucleic polymerase activity|deoxynucleate polymerase activity													molecular_function											owl:Class	
GO:0072762	biolink:NamedThing	cellular response to carbendazim	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbendazim stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2012-11-09T11:48:11Z					biological_process											owl:Class	
GO:1900733	biolink:NamedThing	negative regulation of polyketide biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of polyketide biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of polyketide biosynthetic process|down-regulation of polyketide anabolism|down-regulation of polyketide formation|inhibition of polyketide biosynthesis|negative regulation of polyketide formation|down-regulation of polyketide biosynthesis|negative regulation of polyketide biosynthesis|down-regulation of polyketide synthesis|downregulation of polyketide anabolism|inhibition of polyketide anabolism|down regulation of polyketide biosynthesis|negative regulation of polyketide anabolism|downregulation of polyketide formation|downregulation of polyketide biosynthetic process|inhibition of polyketide formation|downregulation of polyketide biosynthesis|negative regulation of polyketide synthesis|down regulation of polyketide anabolism|down regulation of polyketide formation|downregulation of polyketide synthesis|down regulation of polyketide biosynthetic process|down regulation of polyketide synthesis|inhibition of polyketide synthesis|inhibition of polyketide biosynthetic process							di	2012-05-26T01:30:02Z					biological_process											owl:Class	
GO:1903606	biolink:NamedThing	cytochrome c metabolic process	The chemical reactions and pathways involving cytochrome c.	tmpzr1t_l9r_go_relaxed.owl	cytochrome c metabolism							dph	2014-11-13T20:01:27Z					biological_process											owl:Class	
GO:1904557	biolink:NamedThing	L-alanine transmembrane transport	The directed movement of L-alanine across a membrane.	tmpzr1t_l9r_go_relaxed.owl								pr	2015-08-14T14:21:29Z					biological_process											owl:Class	
GO:0051736	biolink:NamedThing	polyribonucleotide 5'-hydroxyl-kinase activity	Catalysis of the reaction: ATP + 5'-dephospho-RNA = ADP + 5'-phospho-RNA.	tmpzr1t_l9r_go_relaxed.owl	ATP-dependent RNA 5'-hydroxyl-kinase activity|ATP-dependent polyribonucleotide 5'-hydroxyl-kinase activity|ATP-dependent RNA kinase activity|ATP:5'-dephosphopolyribonucleotide 5'-phosphotransferase activity|ATP-dependent polynucleotide 5'-hydroxyl-kinase activity|ATP-dependent polyribonucleotide kinase activity													molecular_function											owl:Class	
GO:1900583	biolink:NamedThing	o-orsellinic acid catabolic process	The chemical reactions and pathways resulting in the breakdown of o-orsellinic acid.	tmpzr1t_l9r_go_relaxed.owl	o-orsellinic acid catabolism|o-orsellinic acid breakdown|o-orsellinic acid degradation							di	2012-05-15T06:48:04Z					biological_process											owl:Class	
GO:0070669	biolink:NamedThing	response to interleukin-2	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-2 stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to IL-2							mah	2009-05-29T09:59:43Z					biological_process											owl:Class	
GO:1904961	biolink:NamedThing	quiescent center organization	The process that contributes to the act of creating the structural organization of the quiescent center. This process pertains to the physical shaping of a rudimentary structure.	tmpzr1t_l9r_go_relaxed.owl	quiescent center structural organization							tb	2016-02-10T00:11:00Z					biological_process											owl:Class	
GO:0021609	biolink:NamedThing	accessory nerve structural organization	The process that contributes to the act of creating the structural organization of the accessory nerve This process pertains to the physical shaping of a rudimentary structure. The spinal branch of this motor nerve innervates the trapezius and the sternocleidomastoid muscles. The cranial branch joins the vagus nerve and innervates the same targets as the vagus nerve.	tmpzr1t_l9r_go_relaxed.owl	CN XI structural organization|accessory nerve structural organisation													biological_process											owl:Class	
GO:1900986	biolink:NamedThing	ajmaline metabolic process	The chemical reactions and pathways involving ajmaline.	tmpzr1t_l9r_go_relaxed.owl	ajmaline metabolism							yaf	2012-06-14T09:47:02Z					biological_process											owl:Class	
GO:1901207	biolink:NamedThing	regulation of heart looping	Any process that modulates the frequency, rate or extent of heart looping.	tmpzr1t_l9r_go_relaxed.owl	regulation of cardiac looping							rl	2012-07-31T07:15:47Z					biological_process											owl:Class	
GO:0090176	biolink:NamedThing	microtubule cytoskeleton organization involved in establishment of planar polarity	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins and contributes to the establishment of planar polarity.	tmpzr1t_l9r_go_relaxed.owl	microtubule cytoskeleton organisation involved in establishment of planar polarity							tb	2009-12-14T10:34:25Z					biological_process											owl:Class	
GO:0051623	biolink:NamedThing	positive regulation of norepinephrine uptake	Any process that activates or increases the frequency, rate or extent of the directed movement of norepinephrine into a cell.	tmpzr1t_l9r_go_relaxed.owl	activation of norepinephrine uptake|stimulation of norepinephrine uptake|up-regulation of norepinephrine uptake|upregulation of norepinephrine uptake|positive regulation of noradrenaline uptake|positive regulation of levarterenol uptake|up regulation of norepinephrine uptake|positive regulation of norepinephrine import													biological_process											owl:Class	
GO:0120304	biolink:NamedThing	integument-mediated background adaptation	Any process in which an organism changes its pigmentation (lightening in response to a brighter environment or darkening in response to a dimmer environment) in response to a change in light intensity detected by light sensitive cells in the integument.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/20524						krc	2021-02-09T18:41:07Z					biological_process											owl:Class	
GO:0010429	biolink:NamedThing	methyl-CpNpN binding	Binding to a methylated cytosine/unspecified/unspecified trinucleotide.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0019243	biolink:NamedThing	methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione	The chemical reactions and pathways resulting in the breakdown of methylglyoxal, CH3-CO-CHO, into D-lactate via the intermediate S-lactoyl-glutathione. Glutathione is used in the first step of the pathway and then regenerated in the second step.	tmpzr1t_l9r_go_relaxed.owl	D-lactate biosynthesis from methylglyoxal|methylglyoxal detoxification|methylglyoxal breakdown to D-lactate|glyoxalase system|methylglyoxal degradation to D-lactate|methylglyoxal catabolism to D-lactate via S-lactoyl-glutathione|D-lactate biosynthetic process from methylglyoxal				MetaCyc:PWY-5386									biological_process											owl:Class	
GO:0007329	biolink:NamedThing	positive regulation of transcription from RNA polymerase II promoter by pheromones	Any process involving pheromones that activates or increases the rate of transcription from an RNA polymerase II promoter.	tmpzr1t_l9r_go_relaxed.owl	stimulation of transcription from RNA polymerase II promoter by pheromones|up regulation of transcription from RNA polymerase II promoter by pheromones|up-regulation of transcription from RNA polymerase II promoter by pheromones|positive regulation of transcription from Pol II promoter by pheromones|upregulation of transcription from RNA polymerase II promoter by pheromones|activation of transcription from RNA polymerase II promoter by pheromones													biological_process											owl:Class	
GO:0009371	biolink:NamedThing	positive regulation of transcription by pheromones	Any process involving pheromones that activates or increases the rate of transcription.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of transcription by pheromones|up regulation of transcription by pheromones|stimulation of transcription by pheromones|upregulation of transcription by pheromones|activation of transcription by pheromones													biological_process											owl:Class	
GO:0034216	biolink:NamedThing	high-affinity thiamine:proton symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: thiamine(out) + H+(out) = thiamine(in) + H+(in). In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.	tmpzr1t_l9r_go_relaxed.owl	high-affinity thiamin:proton symporter activity|high affinity thiamin:hydrogen symporter activity|high-affinity thiamine:hydrogen symporter activity|high-affinity thiamin:hydrogen symporter activity													molecular_function											owl:Class	
GO:0031339	biolink:NamedThing	negative regulation of vesicle fusion	Any process that stops, prevents, or reduces the frequency, rate or extent of vesicle fusion.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of vesicle fusion|inhibition of vesicle fusion|downregulation of vesicle fusion|down regulation of vesicle fusion													biological_process											owl:Class	
GO:0120202	biolink:NamedThing	rod photoreceptor disc membrane	Stack of disc membranes located inside a rod photoreceptor outer segment, and containing densely packed molecules of rhodopsin photoreceptor proteins that traverse the lipid bilayer. It is thought that rod disc membranes arise as evaginations of the ciliary membrane near the base of the outer segment, which then become completely separated from the ciliary membrane, during the development of the rod outer segment.	tmpzr1t_l9r_go_relaxed.owl								krc	2019-05-07T23:27:06Z					cellular_component											owl:Class	
GO:0046525	biolink:NamedThing	xylosylprotein 4-beta-galactosyltransferase activity	Catalysis of the reaction: UDP-galactose + O-beta-D-xylosylprotein = UDP + 4-beta-D-galactosyl-O-beta-D-xylosylprotein.	tmpzr1t_l9r_go_relaxed.owl	UDP-galactose:xylose galactosyltransferase activity|UDPgalactose:O-beta-D-xylosylprotein 4-beta-D-galactosyltransferase activity|UDP-D-galactose:xylose galactosyltransferase activity|UDP-D-galactose:D-xylose galactosyltransferase activity|UDP-galactose:O-beta-D-xylosylprotein 4-beta-D-galactosyltransferase activity|galactosyltransferase I activity|uridine diphosphogalactose-xylose galactosyltransferase activity				EC:2.4.1.133|Reactome:R-HSA-3560804|MetaCyc:2.4.1.133-RXN|Reactome:R-HSA-1889981|RHEA:15297									molecular_function											owl:Class	
GO:0070439	biolink:NamedThing	Mad-Max-mSin3A complex	A transcriptional repressor complex that contains a heterodimer of the bHLH-ZIP proteins Mad and Max, plus mSin3A, a homolog of the yeast Sin3p.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0030432	biolink:NamedThing	peristalsis	A wavelike sequence of involuntary muscular contraction and relaxation that passes along a tubelike structure, such as the intestine, impelling the contents onwards.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Peristalsis									biological_process											owl:Class	
GO:0031050	biolink:NamedThing	dsRNA processing	Cleavage of double-stranded RNA molecules by an RNaseIII-family enzyme to produce small RNAs (generally 20-30 nucleotides, depending on species) with biological function.	tmpzr1t_l9r_go_relaxed.owl	dsRNA fragmentation|double-stranded RNA fragmentation													biological_process											owl:Class	
GO:0002150	biolink:NamedThing	hypochlorous acid catabolic process	The chemical reactions and pathways resulting in the breakdown of hypochlorous acid.	tmpzr1t_l9r_go_relaxed.owl	hypochlorous acid catabolism|HClO catabolic process|hypochlorite catabolic process|HOCl catabolic process							hjd	2009-10-13T10:36:09Z					biological_process											owl:Class	
GO:0044019	biolink:NamedThing	histone acetyltransferase activity (H3-K72 specific)	Catalysis of the reaction: acetyl-CoA + histone H3 L-lysine (position 72) = CoA + histone H3 N6-acetyl-L-lysine (position 72).	tmpzr1t_l9r_go_relaxed.owl	histone lysine N-acetyltransferase activity (H3-K72 specific)													molecular_function											owl:Class	
GO:0031812	biolink:NamedThing	P2Y1 nucleotide receptor binding	Binding to a P2Y1 nucleotide receptor.	tmpzr1t_l9r_go_relaxed.owl	P2Y1 nucleotide receptor ligand													molecular_function											owl:Class	
GO:0035067	biolink:NamedThing	negative regulation of histone acetylation	Any process that stops, prevents, or reduces the frequency, rate or extent of the addition of an acetyl group to a histone protein.	tmpzr1t_l9r_go_relaxed.owl	inhibition of histone acetylation|down-regulation of histone acetylation|down regulation of histone acetylation|downregulation of histone acetylation													biological_process											owl:Class	
GO:2000757	biolink:NamedThing	negative regulation of peptidyl-lysine acetylation	Any process that stops, prevents or reduces the frequency, rate or extent of peptidyl-lysine acetylation.	tmpzr1t_l9r_go_relaxed.owl								yaf	2011-06-16T09:51:31Z					biological_process											owl:Class	
GO:0021614	biolink:NamedThing	glossopharyngeal nerve maturation	A developmental process, independent of morphogenetic (shape) change, that is required for the glossopharyngeal nerve to attain its fully functional state. Various sensory and motor branches of the glossopharyngeal nerve supply nerve connections to the pharynx and back of the tongue. The branchial motor component contains motor fibers that innervate muscles that elevate the pharynx and larynx, and the tympanic branch supplies parasympathetic fibers to the otic ganglion.	tmpzr1t_l9r_go_relaxed.owl	CN IX maturation													biological_process											owl:Class	
GO:1900618	biolink:NamedThing	regulation of shoot system morphogenesis	Any process that modulates the frequency, rate or extent of shoot morphogenesis.	tmpzr1t_l9r_go_relaxed.owl	regulation of shoot morphogenesis							tb	2012-05-15T09:24:37Z					biological_process											owl:Class	
GO:0071485	biolink:NamedThing	cellular response to absence of light	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an absence of light stimuli.	tmpzr1t_l9r_go_relaxed.owl	cellular response to darkness							mah	2009-12-18T02:13:12Z					biological_process											owl:Class	
GO:0009646	biolink:NamedThing	response to absence of light	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an absence of light stimuli.	tmpzr1t_l9r_go_relaxed.owl	response to darkness													biological_process											owl:Class	
GO:0030563	biolink:NamedThing	snRNA 2'-O-ribose methylation guide activity	Activity that provides specificity to a methylase by using base complementarity to guide site-specific 2'-O-ribose methylations to a small nuclear RNA molecule.	tmpzr1t_l9r_go_relaxed.owl						Note that this term describes the activity of a nucleic acid, usually RNA, gene product that interacts with other RNA molecules via base pairing; it should not be used to annotate proteins. Note that this term may be useful for annotating snoRNAs.								molecular_function											owl:Class	
GO:1900286	biolink:NamedThing	negative regulation of cellotriose transport	Any process that stops, prevents or reduces the frequency, rate or extent of cellotriose transport.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of cellotriose transport|down regulation of cellotriose transport|inhibition of cellotriose transport|downregulation of cellotriose transport							tt	2012-04-05T05:56:56Z					biological_process											owl:Class	
GO:0090741	biolink:NamedThing	pigment granule membrane	Any membrane that is part of a pigment granule.	tmpzr1t_l9r_go_relaxed.owl								tb	2017-05-16T22:33:39Z					cellular_component											owl:Class	
GO:0006018	biolink:NamedThing	2-deoxyribose 1-phosphate catabolic process	The chemical reactions and pathways resulting in the breakdown of deoxyribose 1-phosphate, the phosphorylated sugar 1-phospho-2-deoxyribose.	tmpzr1t_l9r_go_relaxed.owl	deoxyribose 1-phosphate catabolic process|2-deoxyribose 1-phosphate breakdown|2-deoxyribose 1-phosphate degradation|2-deoxyribose 1-phosphate catabolism													biological_process											owl:Class	
GO:0045128	biolink:NamedThing	negative regulation of reciprocal meiotic recombination	Any process that decreases the frequency, rate or extent of recombination during meiosis. Reciprocal meiotic recombination is the cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate.	tmpzr1t_l9r_go_relaxed.owl	inhibition of meiotic recombination|down regulation of meiotic recombination|down-regulation of meiotic recombination|downregulation of meiotic recombination|suppression of meiotic recombination													biological_process											owl:Class	
GO:0048917	biolink:NamedThing	posterior lateral line ganglion development	The process whose specific outcome is the progression of the posterior lateral line ganglion over time, from its formation to the mature structure. The posterior lateral line ganglion develops from cranial ectodermal placodes situated behind the ear.	tmpzr1t_l9r_go_relaxed.owl	gPLL development													biological_process											owl:Class	
GO:0010944	biolink:NamedThing	negative regulation of transcription by competitive promoter binding	Any process that stops, prevents, or reduces the frequency, rate or extent of DNA-dependent transcription using a mechanism that involves direct competition for interaction with a promoter binding site.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1900825	biolink:NamedThing	regulation of membrane depolarization during cardiac muscle cell action potential	Any process that modulates the frequency, rate or extent of membrane depolarization during a cardiac muscle cell action potential.	tmpzr1t_l9r_go_relaxed.owl								rl	2012-06-06T04:15:20Z					biological_process											owl:Class	
GO:0030651	biolink:NamedThing	peptide antibiotic biosynthetic process	The chemical reactions and pathways resulting in the formation of peptides with antibiotic activity.	tmpzr1t_l9r_go_relaxed.owl	peptide antibiotic synthesis|peptide antibiotic biosynthesis|peptide antibiotic formation|peptide antibiotic anabolism													biological_process											owl:Class	
GO:0017000	biolink:NamedThing	antibiotic biosynthetic process	The chemical reactions and pathways resulting in the formation of an antibiotic, a substance produced by or derived from certain fungi, bacteria, and other organisms, that can destroy or inhibit the growth of other microorganisms.	tmpzr1t_l9r_go_relaxed.owl	antibiotic synthesis|antibiotic formation|antibiotic biosynthesis|antibiotic anabolism													biological_process											owl:Class	
GO:1990281	biolink:NamedThing	efflux pump complex	A protein complex that is capable of efflux transmembrane transporter activity.	tmpzr1t_l9r_go_relaxed.owl	efflux transmembrane transporter complex|efflux pump							tt	2014-01-31T08:19:53Z					cellular_component											owl:Class	
GO:1900129	biolink:NamedThing	positive regulation of G-protein activated inward rectifier potassium channel activity	Any process that activates or increases the frequency, rate or extent of G-protein activated inward rectifier potassium channel activity.	tmpzr1t_l9r_go_relaxed.owl	upregulation of G-protein activated inward rectifier potassium channel activity|activation of G-protein-activated inward rectifier potassium channel activity|positive regulation of G protein activated inward rectifier potassium channel activity|activation of G protein enhanced inward rectifier potassium channel activity|positive regulation of G-protein-enhanced inward rectifier potassium channel activity|upregulation of G-protein enhanced inward rectifier potassium channel activity|upregulation of G protein activated inward rectifier potassium channel activity|upregulation of G-protein-enhanced inward rectifier potassium channel activity|upregulation of G-protein-activated inward rectifier potassium channel activity|up regulation of G protein enhanced inward rectifier potassium channel activity|up-regulation of G-protein-activated inward rectifier potassium channel activity|up regulation of G protein activated inward rectifier potassium channel activity|up regulation of G-protein-activated inward rectifier potassium channel activity|positive regulation of G-protein-activated inward rectifier potassium channel activity|activation of G-protein activated inward rectifier potassium channel activity|up-regulation of G protein enhanced inward rectifier potassium channel activity|up regulation of G-protein activated inward rectifier potassium channel activity|positive regulation of G-protein enhanced inward rectifier potassium channel activity|up-regulation of G-protein-enhanced inward rectifier potassium channel activity|activation of G protein activated inward rectifier potassium channel activity|up-regulation of G-protein activated inward rectifier potassium channel activity|up-regulation of G protein activated inward rectifier potassium channel activity|up regulation of G-protein enhanced inward rectifier potassium channel activity|activation of G-protein enhanced inward rectifier potassium channel activity|activation of G-protein-enhanced inward rectifier potassium channel activity|up regulation of G-protein-enhanced inward rectifier potassium channel activity|up-regulation of G-protein enhanced inward rectifier potassium channel activity|upregulation of G protein enhanced inward rectifier potassium channel activity|positive regulation of G protein enhanced inward rectifier potassium channel activity							bf	2012-02-23T03:12:58Z					biological_process											owl:Class	
GO:1900128	biolink:NamedThing	regulation of G-protein activated inward rectifier potassium channel activity	Any process that modulates the frequency, rate or extent of G-protein activated inward rectifier potassium channel activity.	tmpzr1t_l9r_go_relaxed.owl	regulation of G protein activated inward rectifier potassium channel activity|regulation of G protein enhanced inward rectifier potassium channel activity|regulation of G-protein-activated inward rectifier potassium channel activity|regulation of G-protein-enhanced inward rectifier potassium channel activity|regulation of G-protein enhanced inward rectifier potassium channel activity							bf	2012-02-23T03:12:53Z					biological_process											owl:Class	
GO:0017196	biolink:NamedThing	N-terminal peptidyl-methionine acetylation	The acetylation of the N-terminal methionine of proteins to form the derivative N-acetyl-L-methionine.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0049									biological_process											owl:Class	
GO:0046432	biolink:NamedThing	2'-(5''-triphosphoribosyl)-3'-dephospho-CoA metabolic process	The chemical reactions and pathways involving 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA, a derivative of coenzyme A.	tmpzr1t_l9r_go_relaxed.owl	2'-(5''-triphosphoribosyl)-3'-dephospho-CoA metabolism													biological_process											owl:Class	
GO:1904426	biolink:NamedThing	positive regulation of GTP binding	Any process that activates or increases the frequency, rate or extent of GTP binding.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of GTP binding|activation of GTP binding|up regulation of GTP binding|upregulation of GTP binding							sl	2015-07-02T20:35:07Z					biological_process											owl:Class	
GO:1905571	biolink:NamedThing	interleukin-10 receptor complex	A protein complex that binds interleukin-10 (IL-10) and that consists of, at a minimum, a dimeric interleukin, an alpha and a beta chain as well as optional additional kinase subunits. The alpha chain binds IL-10 with high affinity and subsequently binds the common beta receptor chain that forms part of multiple interleukin receptors.	tmpzr1t_l9r_go_relaxed.owl	interleukin-10-receptor complex|IL-10 receptor complex|IL-10-receptor complex|IL10 receptor complex					An example of this is IL10RA in human (UniProt symbol Q13651) in PMID:16982608 (inferred from physical interaction).		bhm	2016-10-19T09:45:22Z					cellular_component											owl:Class	
GO:1903705	biolink:NamedThing	positive regulation of production of siRNA involved in RNA interference	Any process that activates or increases the frequency, rate or extent of production of siRNA involved in RNA interference.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of production of guide RNAs involved in RNA interference|positive regulation of RNA interference, production of guide RNAs|positive regulation of RNA interference, production of siRNA|upregulation of production of guide RNAs involved in RNA interference|upregulation of production of siRNA involved in RNA interference|activation of RNA interference, production of guide RNAs|upregulation of RNA interference, production of guide RNAs|up-regulation of RNA interference, production of siRNA|up regulation of production of guide RNAs involved in RNA interference|up regulation of RNA interference, production of siRNA|up-regulation of RNA interference, production of guide RNAs|up-regulation of production of siRNA involved in RNA interference|upregulation of RNA interference, production of siRNA|activation of production of guide RNAs involved in RNA interference|activation of RNA interference, production of siRNA|up regulation of RNA interference, production of guide RNAs|activation of production of siRNA involved in RNA interference|up-regulation of production of guide RNAs involved in RNA interference|up regulation of production of siRNA involved in RNA interference							nc	2014-12-03T15:13:30Z					biological_process											owl:Class	
GO:0120143	biolink:NamedThing	negative regulation of ecdysone receptor-mediated signaling pathway	Any process that stops, prevents, or reduces the frequency, rate or extent of any ecdysone receptor-mediated signaling pathway.	tmpzr1t_l9r_go_relaxed.owl								krc	2018-03-22T17:28:29Z					biological_process											owl:Class	
GO:0034521	biolink:NamedThing	1-naphthoic acid dioxygenase activity	Catalysis of the reaction: 1-naphthoic acid + NADH + O2 + H+ = cis-1,2-dihydroxy-1,2-dihydro-8-carboxynaphthalene + NAD+.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0773|EC:1.14.12.-									molecular_function											owl:Class	
GO:0005736	biolink:NamedThing	RNA polymerase I complex	RNA polymerase I, one of three nuclear DNA-directed RNA polymerases found in all eukaryotes, is a multisubunit complex; typically it produces rRNAs. Two large subunits comprise the most conserved portion including the catalytic site and share similarity with other eukaryotic and bacterial multisubunit RNA polymerases. The remainder of the complex is composed of smaller subunits (generally ten or more), some of which are also found in RNA polymerase III and others of which are also found in RNA polymerases II and III. Although the core is competent to mediate ribonucleic acid synthesis, it requires additional factors to select the appropriate template.	tmpzr1t_l9r_go_relaxed.owl	DNA-directed RNA polymerase I activity|DNA-directed RNA polymerase I complex													cellular_component											owl:Class	
GO:0018025	biolink:NamedThing	calmodulin-lysine N-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + calmodulin L-lysine = S-adenosyl-L-homocysteine + calmodulin N6-methyl-L-lysine.	tmpzr1t_l9r_go_relaxed.owl	S-adenosyl-L-methionine:calmodulin-L-lysine N6-methyltransferase activity|S-adenosylmethionine:calmodulin (lysine) N-methyltransferase activity|S-adenosyl-L-methionine:calmodulin-L-lysine 6-N-methyltransferase activity				RHEA:21556|EC:2.1.1.60|MetaCyc:2.1.1.60-RXN|Reactome:R-HSA-6786205									molecular_function											owl:Class	
GO:1900963	biolink:NamedThing	negative regulation of methanophenazine biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of methanophenazine biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	inhibition of methanophenazine synthesis|inhibition of methanophenazine formation|negative regulation of methanophenazine formation|inhibition of methanophenazine biosynthetic process|downregulation of methanophenazine biosynthetic process|negative regulation of methanophenazine synthesis|negative regulation of methanophenazine biosynthesis|downregulation of methanophenazine anabolism|down regulation of methanophenazine biosynthesis|down regulation of methanophenazine biosynthetic process|inhibition of methanophenazine anabolism|down-regulation of methanophenazine biosynthetic process|down-regulation of methanophenazine synthesis|downregulation of methanophenazine biosynthesis|downregulation of methanophenazine formation|down regulation of methanophenazine anabolism|negative regulation of methanophenazine anabolism|down regulation of methanophenazine formation|inhibition of methanophenazine biosynthesis|down regulation of methanophenazine synthesis|down-regulation of methanophenazine biosynthesis|down-regulation of methanophenazine anabolism|down-regulation of methanophenazine formation|downregulation of methanophenazine synthesis							tt	2012-06-14T03:53:38Z					biological_process											owl:Class	
GO:0000425	biolink:NamedThing	pexophagy	The selective autophagy process in which a peroxisome is degraded by macroautophagy.	tmpzr1t_l9r_go_relaxed.owl	macropexophagy													biological_process											owl:Class	
GO:0035262	biolink:NamedThing	gonad morphogenesis	The process in which the anatomical structures of the gonads are generated and organized. A gonad is an animal organ producing gametes, e.g. the testes or the ovary in mammals.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0042532	biolink:NamedThing	negative regulation of tyrosine phosphorylation of STAT protein	Any process that stops, prevents, or reduces the frequency, rate or extent of the introduction of a phosphate group to a tyrosine residue of a STAT (Signal Transducer and Activator of Transcription) protein.	tmpzr1t_l9r_go_relaxed.owl	downregulation of tyrosine phosphorylation of Stat4 protein|inhibition of tyrosine phosphorylation of Stat5 protein|down-regulation of tyrosine phosphorylation of Stat6 protein|negative regulation of tyrosine phosphorylation of Stat1 protein|downregulation of tyrosine phosphorylation of STAT protein|down regulation of tyrosine phosphorylation of Stat6 protein|down regulation of tyrosine phosphorylation of Stat1 protein|downregulation of tyrosine phosphorylation of Stat2 protein|inhibition of tyrosine phosphorylation of Stat1 protein|down-regulation of tyrosine phosphorylation of Stat1 protein|downregulation of tyrosine phosphorylation of Stat3 protein|down regulation of tyrosine phosphorylation of STAT protein|negative regulation of tyrosine phosphorylation of Stat7 protein|downregulation of tyrosine phosphorylation of Stat1 protein|down regulation of tyrosine phosphorylation of Stat3 protein|down-regulation of tyrosine phosphorylation of Stat7 protein|down-regulation of tyrosine phosphorylation of Stat2 protein|negative regulation of tyrosine phosphorylation of Stat5 protein|down-regulation of tyrosine phosphorylation of STAT protein|down regulation of tyrosine phosphorylation of Stat5 protein|inhibition of tyrosine phosphorylation of Stat3 protein|downregulation of tyrosine phosphorylation of Stat5 protein|downregulation of tyrosine phosphorylation of Stat7 protein|inhibition of tyrosine phosphorylation of STAT protein|down regulation of tyrosine phosphorylation of Stat7 protein|down-regulation of tyrosine phosphorylation of Stat3 protein|negative regulation of tyrosine phosphorylation of Stat2 protein|negative regulation of tyrosine phosphorylation of Stat4 protein|down regulation of tyrosine phosphorylation of Stat4 protein|inhibition of tyrosine phosphorylation of Stat2 protein|down regulation of tyrosine phosphorylation of Stat2 protein|negative regulation of tyrosine phosphorylation of Stat6 protein|negative regulation of tyrosine phosphorylation of Stat3 protein|down-regulation of tyrosine phosphorylation of Stat4 protein|inhibition of tyrosine phosphorylation of Stat6 protein|downregulation of tyrosine phosphorylation of Stat6 protein|inhibition of tyrosine phosphorylation of Stat7 protein|down-regulation of tyrosine phosphorylation of Stat5 protein|inhibition of tyrosine phosphorylation of Stat4 protein											GO:0042512|GO:0042530|GO:0042514|GO:0042521|GO:0042524|GO:0042527|GO:0042518		biological_process											owl:Class	
GO:1905775	biolink:NamedThing	negative regulation of DNA helicase activity	Any process that stops, prevents or reduces the frequency, rate or extent of ATP-dependent DNA helicase activity.	tmpzr1t_l9r_go_relaxed.owl	inhibition of DNA helicase activity|negative regulation of ATP-dependent DNA helicase activity|down regulation of ATP-dependent DNA helicase activity|inhibition of ATP-dependent DNA helicase activity|down regulation of DNA helicase activity|downregulation of DNA helicase activity|down-regulation of ATP-dependent DNA helicase activity|downregulation of ATP-dependent DNA helicase activity|down-regulation of DNA helicase activity							rb	2013-10-15T21:20:01Z			GO:1902450		biological_process											owl:Class	
GO:0018110	biolink:NamedThing	histone arginine kinase activity	Catalysis of the reaction: histone L-arginine + ATP = histone N(omega)-phospho-L-arginine + ADP + 2 H(+).	tmpzr1t_l9r_go_relaxed.owl	histone-arginine kinase activity				EC:2.7.3.-									molecular_function											owl:Class	
GO:0004054	biolink:NamedThing	arginine kinase activity	Catalysis of the reaction: L-arginine + ATP = N(omega)-phospho-L-arginine + ADP + 2 H(+).	tmpzr1t_l9r_go_relaxed.owl	ATP:L-arginine N-phosphotransferase activity|adenosine 5'-triphosphate-arginine phosphotransferase activity|adenosine 5'-triphosphate:L-arginine|arginine phosphokinase activity				RHEA:22940|KEGG_REACTION:R00554|EC:2.7.3.3|MetaCyc:ARGININE-KINASE-RXN									molecular_function											owl:Class	
GO:0034023	biolink:NamedThing	5-(carboxyamino)imidazole ribonucleotide mutase activity	Catalysis of the reaction: 5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole = 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate.	tmpzr1t_l9r_go_relaxed.owl	PurE|class I PurE|N5-CAIR mutase activity|N5-carboxyaminoimidazole ribonucleotide mutase activity|5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole carboxymutase activity				MetaCyc:5.4.99.18-RXN|RHEA:13193|EC:5.4.99.18									molecular_function											owl:Class	
GO:0030677	biolink:NamedThing	ribonuclease P complex	A ribonucleoprotein complex that catalyzes cleavage of the leader sequence of precursor tRNAs (pre-tRNAs), generating the mature 5' end of tRNAs.	tmpzr1t_l9r_go_relaxed.owl	RNase P complex					Note that chloroplasts possess a complex that is called 'RNase P' because it catalyzes pre-tRNA cleavage, but the chloroplast complex appears not to contain RNA.								cellular_component											owl:Class	
GO:0039684	biolink:NamedThing	rolling circle single-stranded viral DNA replication	A rolling circle viral DNA replication that begins with a single-stranded viral DNA genome.	tmpzr1t_l9r_go_relaxed.owl	ssDNA rolling circle replication				VZ:1941			bf	2013-10-17T14:15:48Z					biological_process											owl:Class	
GO:0039682	biolink:NamedThing	rolling circle viral DNA replication	A process of unidirectional viral DNA replication that takes place on a circular DNA to rapidly produce numerous copies of the viral genome. Involves creating a nick in one strand of the circular DNA molecule at the origin of replication. DNA is then synthesized by DNA polymerase. Using the non-nicked strand as a template, replication proceeds around the circular DNA molecule, displacing the nicked strand as single-stranded DNA.	tmpzr1t_l9r_go_relaxed.owl								bf	2013-10-17T14:13:51Z					biological_process											owl:Class	
GO:0009683	biolink:NamedThing	indoleacetic acid metabolic process	The chemical reactions and pathways involving indole-3-acetic acid, a compound which functions as a growth regulator in plants.	tmpzr1t_l9r_go_relaxed.owl	IAA metabolic process|indole acetic acid metabolism|indoleacetic acid metabolism|indole acetic acid metabolic process													biological_process											owl:Class	
GO:0048821	biolink:NamedThing	erythrocyte development	The process whose specific outcome is the progression of an erythrocyte over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl	RBC development|red blood cell development													biological_process											owl:Class	
GO:0006696	biolink:NamedThing	ergosterol biosynthetic process	The chemical reactions and pathways resulting in the formation of ergosterol, (22E)-ergosta-5,7,22-trien-3-beta-ol, a sterol found in ergot, yeast and moulds.	tmpzr1t_l9r_go_relaxed.owl	ergosterol formation|ergosterol biosynthesis|ergosterol synthesis|ergosterol anabolism													biological_process											owl:Class	
GO:1901588	biolink:NamedThing	dendritic microtubule	Any microtubule in a dendrite, a neuron projection.	tmpzr1t_l9r_go_relaxed.owl	microtubule of dendrite|microtubulus of dendrite				NIF_Subcellular:sao110773650			pr	2012-11-07T14:37:30Z					cellular_component											owl:Class	
GO:0008247	biolink:NamedThing	1-alkyl-2-acetylglycerophosphocholine esterase complex	An enzyme complex composed of two catalytic alpha subunits, which form a catalytic dimer, and a non-catalytic, regulatory beta subunit; the catalytic dimer may be an alpha1/alpha1 or alpha2/alpha2 homodimer, or an alpha1/alpha2 heterodimer. Modulates the action of platelet-activating factor (PAF).	tmpzr1t_l9r_go_relaxed.owl	2-acetyl-1-alkylglycerophosphocholine esterase complex|platelet-activating factor acetylhydrolase complex					See also the molecular function term '1-alkyl-2-acetylglycerophosphocholine esterase activity ; GO:0003847'.								cellular_component											owl:Class	
GO:0140467	biolink:NamedThing	integrated stress response signaling	The series of molecular signals generated in response to diverse stress stimuli required to restore cellular homeostasis. The core event in this pathway is the phosphorylation of eIF2 alpha by one of four members of the eIF2a kinase family (EIF2AK1/HRI, EIF2AK2/PKR, EIF2AK3/PERK and EIF2AK4/GCN2), which leads to a decrease in global protein synthesis and the induction of selected genes, including the transcription factor ATF4, that together promote cellular recovery.	tmpzr1t_l9r_go_relaxed.owl	ISR	https://github.com/geneontology/go-ontology/issues/19153			Wikipedia:Integrated_stress_response			pg	2020-05-26T08:04:10Z					biological_process											owl:Class	
GO:0051507	biolink:NamedThing	beta-sitosterol UDP-glucosyltransferase activity	Catalysis of the reaction: UDP-glucose + a beta-sitosterol = UDP + O-glucosyl-beta-sitosterol.	tmpzr1t_l9r_go_relaxed.owl					RHEA:61832|MetaCyc:RXN-12128									molecular_function											owl:Class	
GO:0016906	biolink:NamedThing	sterol 3-beta-glucosyltransferase activity	Catalysis of the reaction: UDP-glucose + a sterol = UDP + an O-glucosylsterol.	tmpzr1t_l9r_go_relaxed.owl	sterol 3beta-glucosyltransferase activity|sterol glucosyltransferase activity|UDPG-SGTase activity|sterol:UDPG glucosyltransferase activity|UDP-glucose:sterol 3-O-beta-D-glucosyltransferase activity|uridine diphosphoglucose-sterol glucosyltransferase activity|UDP-glucose-sterol glucosyltransferase activity|uridine diphosphoglucose-poriferasterol glucosyltransferase activity|UDPG:sterol glucosyltransferase activity|UDP-glucose-sterol beta-glucosyltransferase activity|sterol-beta-D-glucosyltransferase activity|UDPglucose:sterol 3-O-beta-D-glucosyltransferase activity|UDP-glucose:sterol glucosyltransferase activity				EC:2.4.1.173|MetaCyc:STEROL-GLUCOSYLTRANSFERASE-RXN|RHEA:22724									molecular_function											owl:Class	
GO:2001206	biolink:NamedThing	positive regulation of osteoclast development	Any process that activates or increases the frequency, rate or extent of osteoclast development.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of osteoclast cell development							yaf	2011-11-10T10:59:12Z					biological_process											owl:Class	
GO:0015451	biolink:NamedThing	decarboxylation-driven active transmembrane transporter activity	Primary active transport of a solute across a membrane driven by decarboxylation of a cytoplasmic substrate. Primary active transport is catalysis of the transport of a solute across a membrane, up the solute's concentration gradient, by binding the solute and undergoing a series of conformational changes. Transport works equally well in either direction and is driven by a primary energy source.	tmpzr1t_l9r_go_relaxed.owl	decarboxylation-driven transporter				EC:7.2.4.4|EC:7.2.4.3|EC:7.2.4.2|TC:3.B|EC:7.2.4.5|EC:7.2.4.1									molecular_function											owl:Class	
GO:0015399	biolink:NamedThing	primary active transmembrane transporter activity	Enables the transfer of a solute from one side of a membrane to the other, up the solute's concentration gradient, by binding the solute and undergoing a series of conformational changes. Transport works equally well in either direction and is powered by a primary energy source, directly using ATP. Primary energy sources known to be coupled to transport are chemical, electrical and solar sources.	tmpzr1t_l9r_go_relaxed.owl	primary active transporter				TC:3									molecular_function											owl:Class	
GO:0043660	biolink:NamedThing	bacteroid-containing symbiosome	A symbiosome containing any of various structurally modified bacteria, such as those occurring on the root nodules of leguminous plants.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0043659	biolink:NamedThing	symbiosome	A double-enveloped cell compartment, composed of an endosymbiont with its plasmalemma (as inner envelope) and a non-endosymbiotic outer envelope (the perisymbiontic membrane).	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0010331	biolink:NamedThing	gibberellin binding	Binding to a gibberellin, a plant hormone that regulates aspects of plant growth.	tmpzr1t_l9r_go_relaxed.owl	gibberellin receptor|gibberellic acid receptor													molecular_function											owl:Class	
GO:1904511	biolink:NamedThing	cytoplasmic microtubule plus-end	Any microtubule plus-end that is part of a cytoplasmic microtubule.	tmpzr1t_l9r_go_relaxed.owl	growing microtubule plus end of cytoplasmic microtubule|microtubule plus end of non-spindle-associated astral microtubule|microtubule plus-end of non-spindle-associated astral microtubule|microtubule plus end of cytoplasmic microtubule|microtubule plus-end of cytoplasmic microtubule|growing microtubule plus end of non-spindle-associated astral microtubule							mah	2015-07-27T13:05:11Z					cellular_component											owl:Class	
GO:2001054	biolink:NamedThing	negative regulation of mesenchymal cell apoptotic process	Any process that stops, prevents or reduces the frequency, rate or extent of mesenchymal cell apoptotic process.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of mesenchymal cell apoptosis							yaf	2011-09-08T02:50:05Z					biological_process											owl:Class	
GO:2001053	biolink:NamedThing	regulation of mesenchymal cell apoptotic process	Any process that modulates the frequency, rate or extent of mesenchymal cell apoptotic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of mesenchymal cell apoptosis							yaf	2011-09-08T02:49:59Z					biological_process											owl:Class	
GO:1900938	biolink:NamedThing	regulation of (Z)-nonadeca-1,14-diene metabolic process	Any process that modulates the frequency, rate or extent of (Z)-nonadeca-1,14-diene metabolic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of (Z)-nonadeca-1,14-diene metabolism							tt	2012-06-14T03:15:37Z					biological_process											owl:Class	
GO:1904980	biolink:NamedThing	positive regulation of endosome organization	Any process that activates or increases the frequency, rate or extent of endosome organization.	tmpzr1t_l9r_go_relaxed.owl	activation of endosome organisation|activation of endosome organization and biogenesis|up-regulation of endosome organization|upregulation of endosome organisation|up-regulation of endosome organisation|upregulation of endosome organization and biogenesis|positive regulation of endosome organization and biogenesis|up regulation of endosome organisation|up regulation of endosome organization|upregulation of endosome organization|up-regulation of endosome organization and biogenesis|up regulation of endosome organization and biogenesis|activation of endosome organization|positive regulation of endosome organisation							pad	2016-02-22T19:21:16Z					biological_process											owl:Class	
GO:1904978	biolink:NamedThing	regulation of endosome organization	Any process that modulates the frequency, rate or extent of endosome organization.	tmpzr1t_l9r_go_relaxed.owl	regulation of endosome organization and biogenesis|regulation of endosome organisation							pad	2016-02-22T19:21:01Z					biological_process											owl:Class	
GO:1903433	biolink:NamedThing	regulation of constitutive secretory pathway	Any process that modulates the frequency, rate or extent of constitutive secretory pathway.	tmpzr1t_l9r_go_relaxed.owl								als	2014-09-15T15:07:31Z					biological_process											owl:Class	
GO:1905164	biolink:NamedThing	positive regulation of phagosome maturation	Any process that activates or increases the frequency, rate or extent of phagosome maturation.	tmpzr1t_l9r_go_relaxed.owl	activation of phagosome maturation|up-regulation of phagosome maturation|up regulation of phagosome maturation|upregulation of phagosome maturation							bf	2016-04-25T16:28:19Z					biological_process											owl:Class	
GO:0050284	biolink:NamedThing	sinapate 1-glucosyltransferase activity	Catalysis of the reaction: UDP-glucose + sinapate = UDP + 1-sinapoyl-D-glucose.	tmpzr1t_l9r_go_relaxed.owl	UDPglucose:sinapic acid glucosyltransferase activity|UDP-glucose:sinapate D-glucosyltransferase activity|UDPglucose:sinapate D-glucosyltransferase activity|uridine diphosphoglucose-sinapate glucosyltransferase activity|uridine 5'-diphosphoglucose-hydroxycinnamic acid acylglucosyltransferase activity				RHEA:13305|MetaCyc:SINAPATE-1-GLUCOSYLTRANSFERASE-RXN|EC:2.4.1.120									molecular_function											owl:Class	
GO:0031390	biolink:NamedThing	Ctf18 RFC-like complex	A heptameric complex related to replication factor C, which loads the DNA polymerase processivity factor proliferating cell nuclear antigen (PCNA) onto DNA and plays a vital role in chromosome cohesion. In Saccharomyces the subunits are known as Ctf18p, Rfc2p, Rfc3p, Rfc4p, Rfc5p, Dcc1p, and Ctf8p.	tmpzr1t_l9r_go_relaxed.owl	Ctf18-RLC|RFC (Ctf18)|Ctf18-RFC													cellular_component											owl:Class	
GO:0006334	biolink:NamedThing	nucleosome assembly	The aggregation, arrangement and bonding together of a nucleosome, the beadlike structural units of eukaryotic chromatin composed of histones and DNA.	tmpzr1t_l9r_go_relaxed.owl	nucleosome modeling|histone chaperone													biological_process											owl:Class	
GO:0032718	biolink:NamedThing	negative regulation of interleukin-9 production	Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-9 production.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of interleukin-9 biosynthetic process|inhibition of interleukin-9 production|down regulation of interleukin-9 production|down-regulation of interleukin-9 production|negative regulation of IL-9 production|downregulation of interleukin-9 production											GO:0045418		biological_process											owl:Class	
GO:0030839	biolink:NamedThing	regulation of intermediate filament polymerization	Any process that modulates the frequency, rate or extent of the assembly of intermediate filaments by the addition of monomers to a filament.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0072011	biolink:NamedThing	glomerular endothelium development	The process whose specific outcome is the progression of the glomerular endothelium over time, from its formation to the mature structure. The glomerular endothelium is an epithelial tissue that covers the internal surfaces of the glomerulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-01-25T02:02:57Z					biological_process											owl:Class	
GO:1905385	biolink:NamedThing	negative regulation of protein localization to presynapse	Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to presynapse.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of protein localisation to presynapse|downregulation of protein localisation to presynapse|down regulation of protein localization to presynapse|negative regulation of recruitment of presynaptic proteins|downregulation of recruitment of presynaptic proteins|down regulation of protein localisation in presynapse|negative regulation of protein localization in presynapse|down-regulation of recruitment of presynaptic proteins|downregulation of protein localisation in presynapse|downregulation of protein localization to presynapse|down regulation of protein localisation to presynapse|inhibition of protein localisation in presynapse|down regulation of recruitment of presynaptic proteins|inhibition of recruitment of presynaptic proteins|inhibition of protein localization in presynapse|inhibition of protein localization to presynapse|down-regulation of protein localisation to presynapse|down regulation of protein localization in presynapse|downregulation of protein localization in presynapse|down-regulation of protein localisation in presynapse|negative regulation of protein localisation in presynapse|down-regulation of protein localization to presynapse|down-regulation of protein localization in presynapse|inhibition of protein localisation to presynapse							dos	2016-08-18T14:56:08Z					biological_process											owl:Class	
GO:1905384	biolink:NamedThing	regulation of protein localization to presynapse	Any process that modulates the frequency, rate or extent of protein localization to presynapse.	tmpzr1t_l9r_go_relaxed.owl	regulation of protein localisation to presynapse|regulation of recruitment of presynaptic proteins|regulation of protein localisation in presynapse|regulation of protein localization in presynapse							dos	2016-08-18T14:56:00Z					biological_process											owl:Class	
GO:0043419	biolink:NamedThing	urea catabolic process	The chemical reactions and pathways resulting in the breakdown of urea, the water soluble compound O=C-(NH2)2.	tmpzr1t_l9r_go_relaxed.owl	urea decomposition|urea degradation|urea breakdown|urea catabolism													biological_process											owl:Class	
GO:0043605	biolink:NamedThing	cellular amide catabolic process	The chemical reactions and pathways resulting in the breakdown of an amide, any derivative of an oxoacid in which an acidic hydroxy group has been replaced by an amino or substituted amino group.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0097379	biolink:NamedThing	dorsal spinal cord interneuron posterior axon guidance	The process in which the migration of an axon growth cone of a dorsal spinal cord interneuron is directed to a specific target site in the posterior direction along the anterior-posterior body axis in response to a combination of attractive and repulsive cues. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism.	tmpzr1t_l9r_go_relaxed.owl	dorsal interneuron caudal axon projection							pr	2012-10-01T10:22:38Z					biological_process											owl:Class	
GO:0097378	biolink:NamedThing	dorsal spinal cord interneuron axon guidance	The process in which the migration of an axon growth cone of a dorsal spinal cord interneuron is directed to a specific target site in response to a combination of attractive and repulsive cues. A dorsal spinal cord interneuron is an interneuron located in the dorsal part of the spinal cord.	tmpzr1t_l9r_go_relaxed.owl	dorsal interneuron axon guidance							pr	2012-10-01T10:20:48Z					biological_process											owl:Class	
GO:0036013	biolink:NamedThing	cyanelle outer membrane	The outer, i.e. cytoplasm-facing, lipid bilayer of the cyanelle envelope.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-10-10T01:50:56Z					cellular_component											owl:Class	
GO:0017143	biolink:NamedThing	insecticide metabolic process	The chemical reactions and pathways involving insecticides, chemicals used to kill insects.	tmpzr1t_l9r_go_relaxed.owl	insecticide metabolism											GO:0017138		biological_process											owl:Class	
GO:0039509	biolink:NamedThing	suppression by virus of host pattern recognition receptor activity	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of the functional activity of a host pattern recognition receptor. A pattern recognition receptor combines with a molecular pattern based on a repeating or polymeric structure, such as a polysaccharide or peptidoglycan, to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	down regulation by virus of host pattern recognition receptor activity|suppression by virus of host pattern recognition receptor function|inhibition by virus of host pattern recognition receptor activity|viral inhibition of host pattern recognition receptor activity|down-regulation by virus of host pattern recognition receptor activity|negative regulation by virus of host pattern recognition receptor activity							bf	2011-06-02T03:11:23Z					biological_process											owl:Class	
GO:0039508	biolink:NamedThing	suppression by virus of host receptor activity	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of the functional activity of a host receptor.	tmpzr1t_l9r_go_relaxed.owl	downregulation by virus of host receptor activity|negative regulation by virus of host receptor activity|viral inhibition of host receptor|suppression by virus of host receptor function|inhibition by virus of host receptor activity|down-regulation by virus of host receptor activity							bf	2011-06-02T03:09:37Z					biological_process											owl:Class	
GO:0120277	biolink:NamedThing	positive regulation of cerebral blood circulation	Any process that activates or increases the frequency, rate or extent of cerebral blood circulation.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of telencephalon blood circulation|up-regulation of cerebral blood circulation|activation of cerebral blood circulation|positive regulation of cerebrum blood circulation|up regulation of cerebral blood circulation|upregulation of cerebral blood circulation	https://github.com/geneontology/go-ontology/issues/20107						krc	2020-10-21T06:55:42Z					biological_process											owl:Class	
GO:0005750	biolink:NamedThing	mitochondrial respiratory chain complex III	A protein complex located in the mitochondrial inner membrane that forms part of the mitochondrial respiratory chain. Contains about 10 polypeptide subunits including four redox centers: cytochrome b/b6, cytochrome c1 and an 2Fe-2S cluster. Catalyzes the oxidation of ubiquinol by oxidized cytochrome c1.	tmpzr1t_l9r_go_relaxed.owl	mitochondrial complex III|mitochondrial cytochrome bc(1) complex|mitochondrial electron transport complex III|mitochondrial coenzyme Q-cytochrome c reductase complex|mitochondrial ubiquinol-cytochrome-c reductase complex|mitochondrial cytochrome bc1 complex|mitochondrial ubiquinol-cytochrome c oxidoreductase complex|mitochondrial coenzyme Q-cytochrome c oxidoreductase complex											GO:0015008		cellular_component											owl:Class	
GO:0045275	biolink:NamedThing	respiratory chain complex III	A protein complex that transfers electrons from ubiquinol to cytochrome c and translocates two protons across a membrane. The complex contains a core structure of three catalytic subunits: cytochrome b, the Rieske iron sulfur protein (ISP), and cytochrome c1, which are arranged in an integral membrane-bound dimeric complex; additional subunits are present, and vary among different species.	tmpzr1t_l9r_go_relaxed.owl	coenzyme Q-cytochrome c reductase complex|complex III|ubiquinol-cytochrome-c reductase complex|coenzyme Q-cytochrome c oxidoreductase complex|ubiquinol-cytochrome c oxidoreductase complex|cytochrome bc1 complex|cytochrome bc(1) complex|CoQH2-cytochrome c reductase complex|electron transport complex III				Wikipedia:Coenzyme_Q_-_cytochrome_c_reductase							GO:0045285|GO:0032842		cellular_component											owl:Class	
GO:0043833	biolink:NamedThing	methylamine-specific methylcobalamin:coenzyme M methyltransferase activity	Catalysis of the reaction: a methylated methylamine corrinoid protein + coenzyme M = a methylamine corrinoid protein + methyl-CoM. This reaction is the transfer of the methyl group from the methylated corrinoid cofactor of a methylamine corrinoid protein to coenzyme M.	tmpzr1t_l9r_go_relaxed.owl	methylamine-specific methylcobalamin:CoM methyltransferase activity|methylcobamide:CoM methyltransferase activity|monomethylamine-specific methylcobalamin:coenzyme M methyltransferase activity|methylcobamide:CoM methyltransferase II isozyme A|methylcobamide:coenzyme M methyltransferase activity				EC:2.1.1.247|MetaCyc:RXN-8099|MetaCyc:RXN-8103|MetaCyc:RXN-8101	This function is the second step in the pathway of methanogenesis from monomethylamine, dimethylamine and trimethylamine.								molecular_function											owl:Class	
GO:0075261	biolink:NamedThing	positive regulation of spore-bearing organ development	Any process that activates, maintains or increases the frequency, rate or extent of spore-bearing organ development, a process in which hyphae grow into special aggregates called fruiting bodies that produce new spores.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0010728	biolink:NamedThing	regulation of hydrogen peroxide biosynthetic process	Any process that modulates the rate, frequency or extent of hydrogen peroxide biosynthesis. The chemical reactions and pathways resulting in the formation of hydrogen peroxide (H2O2), a potentially harmful byproduct of aerobic cellular respiration which can cause damage to DNA.	tmpzr1t_l9r_go_relaxed.owl	regulation of hydrogen peroxide biosynthesis													biological_process											owl:Class	
GO:0039631	biolink:NamedThing	DNA translocase activity involved in viral DNA genome packaging	Catalysis of the reaction: ATP + H2O = ADP + phosphate, to drive movement along a single- or double-stranded DNA molecule, that contributes to the packing of viral DNA into a capsid.	tmpzr1t_l9r_go_relaxed.owl	viral DNA packaging activity|viral DNA packaging motor activity							bf	2012-08-07T11:17:07Z					molecular_function											owl:Class	
GO:0048139	biolink:NamedThing	female germ-line cyst encapsulation	Formation of a single follicular epithelium around the germ-line derived cells of a cyst formed in the female gonad.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0008441	biolink:NamedThing	3'(2'),5'-bisphosphate nucleotidase activity	Catalysis of the reaction: adenosine 3',5'-bisphosphate + H2O = adenosine 5'-phosphate + phosphate.	tmpzr1t_l9r_go_relaxed.owl	3'-phosphoadenylylsulfate 3'-phosphatase activity|adenosine-3'(2'),5'-bisphosphate 3'(2')-phosphohydrolase activity|DPNPase activity|3'(2'),5' bisphosphate nucleotidase activity|phosphoadenylate 3'-nucleotidase activity|3'(2'),5'-bisphosphonucleoside 3'(2')-phosphohydrolase activity				Reactome:R-HSA-8953499|Reactome:R-HSA-176606|RHEA:10040|MetaCyc:325-BISPHOSPHATE-NUCLEOTIDASE-RXN|EC:3.1.3.7									molecular_function											owl:Class	
GO:0008252	biolink:NamedThing	nucleotidase activity	Catalysis of the reaction: a nucleotide + H2O = a nucleoside + phosphate.	tmpzr1t_l9r_go_relaxed.owl	nucleotide-specific phosphatase activity|acid nucleotidase activity|NSP II|deoxyribonucleoside-activated nucleotidase (DAN)|nucleotide phosphohydrolase activity|NSP I|deoxyinosine-activated nucleotidase (DIAN)				MetaCyc:NUCLEOTIDASE-RXN|RHEA:22140									molecular_function											owl:Class	
GO:1902949	biolink:NamedThing	positive regulation of tau-protein kinase activity	Any process that activates or increases the frequency, rate or extent of tau-protein kinase activity.	tmpzr1t_l9r_go_relaxed.owl	activation of STK31|positive regulation of glycogen synthase kinase-3beta activity|positive regulation of tau kinase activity|upregulation of protein tau kinase activity|up-regulation of STK31|up-regulation of tau-protein kinase I activity|upregulation of tau-protein kinase activity|activation of tau protein kinase activity|upregulation of TPK I|positive regulation of TPK II|upregulation of cdk5/p20|positive regulation of GSK|upregulation of tau-tubulin kinase activity|upregulation of tau-protein kinase II activity|up-regulation of TTK|positive regulation of cdk5/p20|up-regulation of TPK|up-regulation of GSK|positive regulation of CDK5/p23|up regulation of GSK|activation of GSK|activation of protein tau kinase activity|upregulation of glycogen synthase kinase-3beta activity|activation of [Tau protein] kinase activity|up regulation of TTK|up regulation of protein tau kinase activity|positive regulation of TTK|positive regulation of tau protein kinase activity|positive regulation of brain protein kinase PK40erk activity|positive regulation of protein tau kinase activity|upregulation of TPK|positive regulation of STK31|activation of CDK5/p23|up regulation of tau-tubulin kinase activity|up regulation of glycogen synthase kinase-3beta activity|upregulation of GSK|activation of tau-protein kinase I activity|activation of tau kinase activity|up regulation of brain protein kinase PK40erk activity|up regulation of CDK5/p23|upregulation of CDK5/p23|activation of tau-tubulin kinase activity|up-regulation of tau-tubulin kinase activity|positive regulation of TPK I|up-regulation of tau-protein kinase activity|activation of brain protein kinase PK40erk activity|upregulation of [Tau protein] kinase activity|up-regulation of tau-protein kinase II activity|up regulation of tau-protein kinase II activity|up-regulation of protein tau kinase activity|activation of TPK I|upregulation of TTK|positive regulation of tau-protein kinase I activity|activation of tau-protein kinase activity|up regulation of tau kinase activity|activation of TPK II|up-regulation of TPK II|activation of glycogen synthase kinase-3beta activity|upregulation of brain protein kinase PK40erk activity|activation of TPK|positive regulation of TPK|up-regulation of tau kinase activity|up-regulation of [Tau protein] kinase activity|up regulation of [Tau protein] kinase activity|upregulation of tau kinase activity|up regulation of TPK|up-regulation of TPK I|up-regulation of glycogen synthase kinase-3beta activity|positive regulation of tau-tubulin kinase activity|upregulation of tau protein kinase activity|up regulation of TPK II|up regulation of tau protein kinase activity|up regulation of STK31|activation of cdk5/p20|upregulation of TPK II|up-regulation of tau protein kinase activity|up-regulation of CDK5/p23|up regulation of tau-protein kinase activity|activation of TTK|up regulation of cdk5/p20|positive regulation of tau-protein kinase II activity|up regulation of TPK I|up-regulation of cdk5/p20|up regulation of tau-protein kinase I activity|up-regulation of brain protein kinase PK40erk activity|upregulation of tau-protein kinase I activity|positive regulation of [Tau protein] kinase activity|activation of tau-protein kinase II activity|upregulation of STK31							sjp	2014-05-02T08:43:38Z					biological_process											owl:Class	
GO:0016101	biolink:NamedThing	diterpenoid metabolic process	The chemical reactions and pathways involving diterpenoid compounds, terpenoids with four isoprene units.	tmpzr1t_l9r_go_relaxed.owl	diterpene metabolic process|diterpenoid metabolism|diterpene metabolism													biological_process											owl:Class	
GO:0031712	biolink:NamedThing	B1 bradykinin receptor binding	Binding to a B1 bradykinin receptor.	tmpzr1t_l9r_go_relaxed.owl	B1 bradykinin receptor ligand													molecular_function											owl:Class	
GO:0031711	biolink:NamedThing	bradykinin receptor binding	Binding to a bradykinin receptor.	tmpzr1t_l9r_go_relaxed.owl	bradykinin receptor ligand													molecular_function											owl:Class	
GO:0043322	biolink:NamedThing	negative regulation of natural killer cell degranulation	Any process that stops, prevents, or reduces the rate of natural killer cell degranulation.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of natural killer cell degranulation|negative regulation of NK cell granule exocytosis|negative regulation of NK cell degranulation|inhibition of natural killer cell degranulation|downregulation of natural killer cell degranulation|negative regulation of natural killer cell granule exocytosis|down regulation of natural killer cell degranulation													biological_process											owl:Class	
GO:1902509	biolink:NamedThing	methionine-importing complex	A protein complex which is capable of methionine-importing activity.	tmpzr1t_l9r_go_relaxed.owl	methionine importing complex|methionine importer complex							pr	2013-11-15T10:42:41Z					cellular_component											owl:Class	
GO:2000855	biolink:NamedThing	regulation of mineralocorticoid secretion	Any process that modulates the frequency, rate or extent of mineralocorticoid secretion.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-07-26T08:46:38Z					biological_process											owl:Class	
GO:0106339	biolink:NamedThing	tRNA (cytidine 32-2'-O)-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + cytosine32 in tRNA= S-adenosyl-L-homocysteine + 2'-O-methylcytidine32 in tRNA.	tmpzr1t_l9r_go_relaxed.owl								hjd	2020-11-05T22:48:53Z					molecular_function											owl:Class	
GO:0052666	biolink:NamedThing	tRNA (cytosine-2'-O-)-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing 2'-O-methylcytosine.	tmpzr1t_l9r_go_relaxed.owl	transfer ribonucleate cytosine 2'-methyltransferase activity|tRNA cytosine 2'-methyltransferase activity|tRNA (cytosine 2')-methyltransferase activity|S-adenosyl-L-methionine:tRNA (cytosine-2'-O-)-methyltransferase activity|tRNA cytosine-2'-O-methyltransferase activity|S-adenosyl-L-methionine:tRNA cytosine-2'-O-methyltransferase activity				Reactome:R-HSA-9024159|Reactome:R-HSA-6788668|Reactome:R-HSA-6788684|MetaCyc:RXN0-5143			ai	2010-10-11T01:05:47Z					molecular_function											owl:Class	
GO:1905013	biolink:NamedThing	negative regulation of 'de novo' NAD biosynthetic process from tryptophan	Any process that stops, prevents or reduces the frequency, rate or extent of 'de novo' NAD biosynthetic process from tryptophan.	tmpzr1t_l9r_go_relaxed.owl	down regulation of 'de novo' NAD biosynthetic process from tryptophan|downregulation of de novo NAD biosynthetic process from tryptophan|down regulation of de novo NAD biosynthetic process from tryptophan|down-regulation of de novo NAD biosynthetic process from tryptophan|down-regulation of 'de novo' NAD biosynthetic process from tryptophan|negative regulation of de novo NAD biosynthetic process from tryptophan|inhibition of 'de novo' NAD biosynthetic process from tryptophan|inhibition of de novo NAD biosynthetic process from tryptophan|downregulation of 'de novo' NAD biosynthetic process from tryptophan							bf	2016-03-03T10:01:00Z					biological_process											owl:Class	
GO:0050989	biolink:NamedThing	N-terminal protein amino acid carboxylation	The carboxylation of the N-terminal amino acid of proteins.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0039657	biolink:NamedThing	suppression by virus of host gene expression	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of gene expression in the host organism. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Some protein processing events may be included when they are required to form an active form of a product from an inactive precursor form.	tmpzr1t_l9r_go_relaxed.owl	host gene expression shutoff by virus				VZ:1582			bf	2013-06-20T15:29:55Z					biological_process											owl:Class	
GO:0051503	biolink:NamedThing	adenine nucleotide transport	The directed movement of adenine nucleotides, ATP, ADP, and/or AMP, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0033922	biolink:NamedThing	peptidoglycan beta-N-acetylmuramidase activity	Catalysis of the hydrolysis of terminal, non-reducing N-acetylmuramic residues.	tmpzr1t_l9r_go_relaxed.owl	beta-2-acetamido-3-O-(D-1-carboxyethyl)-2-deoxy-D-glucoside acetamidodeoxyglucohydrolase activity|exo-beta-N-acetylmuramidase activity|peptidoglycan beta-N-acetylmuramoylexohydrolase activity|exo-beta-acetylmuramidase activity				EC:3.2.1.92|MetaCyc:3.2.1.92-RXN									molecular_function											owl:Class	
GO:1905247	biolink:NamedThing	positive regulation of aspartic-type peptidase activity	Any process that activates or increases the frequency, rate or extent of aspartic-type peptidase activity.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of aspartic-type peptidase activity|activation of aspartic-type peptidase activity|up regulation of aspartic-type peptidase activity|upregulation of aspartic-type peptidase activity							jl	2016-06-09T11:55:55Z					biological_process											owl:Class	
GO:0071370	biolink:NamedThing	cellular response to gibberellin stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gibberellin stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to gibberellic acid stimulus							mah	2009-12-11T03:14:21Z					biological_process											owl:Class	
GO:0033480	biolink:NamedThing	UDP-D-galacturonate biosynthetic process	The chemical reactions and pathways resulting in the formation of UDP-D-galacturonate, a substance composed of galacturonic acid in glycosidic linkage with uridine diphosphate.	tmpzr1t_l9r_go_relaxed.owl	UDP-D-galacturonate anabolism|UDP-D-galacturonate synthesis|UDP-D-galacturonate formation|UDP-D-galacturonate biosynthesis				MetaCyc:PWY-4									biological_process											owl:Class	
GO:0033479	biolink:NamedThing	UDP-D-galacturonate metabolic process	The chemical reactions and pathways involving UDP-D-galacturonate, a substance composed of galacturonic acid in glycosidic linkage with uridine diphosphate.	tmpzr1t_l9r_go_relaxed.owl	UDP-D-galacturonate metabolism													biological_process											owl:Class	
GO:2000459	biolink:NamedThing	negative regulation of astrocyte chemotaxis	Any process that stops, prevents or reduces the frequency, rate or extent of astrocyte chemotaxis.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-03-04T10:54:28Z					biological_process											owl:Class	
GO:0090518	biolink:NamedThing	L-arginine transmembrane import into vacuole	The directed movement of L-arginine into the vacuole across the vacuolar membrane.	tmpzr1t_l9r_go_relaxed.owl	arginine transmembrane import into vacuole|vacuolar arginine import							tb	2012-09-24T14:12:46Z			GO:0090458		biological_process											owl:Class	
GO:0034490	biolink:NamedThing	basic amino acid transmembrane import into vacuole	The directed movement of basic amino acids into the vacuole across the vacuolar membrane.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0034276	biolink:NamedThing	kynurenic acid biosynthetic process	The chemical reactions and pathways resulting in the formation of kynurenic acid, 4-hydroxyquinoline-2-carboxylic acid.	tmpzr1t_l9r_go_relaxed.owl	4-hydroxyquinoline-2-carboxylic acid biosynthetic process|kynurenic acid formation|kynurenic acid biosynthesis|kynurenic acid synthesis|kynurenic acid anabolism													biological_process											owl:Class	
GO:0051465	biolink:NamedThing	negative regulation of corticotropin-releasing hormone secretion	Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of corticotropin-releasing hormone from a cell.	tmpzr1t_l9r_go_relaxed.owl	inhibition of corticotropin-releasing hormone secretion|negative regulation of corticotropin-releasing factor secretion|downregulation of corticotropin-releasing hormone secretion|down regulation of corticotropin-releasing hormone secretion|negative regulation of CRH secretion|down-regulation of corticotropin-releasing hormone secretion|negative regulation of CRF secretion													biological_process											owl:Class	
GO:0060875	biolink:NamedThing	lateral semicircular canal development	The progession of the lateral semicircular canal from its initial formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-08-13T09:43:25Z					biological_process											owl:Class	
GO:0034899	biolink:NamedThing	trimethylamine monooxygenase activity	Catalysis of the reaction: N,N,N-trimethylamine + NADPH + H+ + O2 = N,N,N-trimethylamine N-oxide + NADP+ + H2O.	tmpzr1t_l9r_go_relaxed.owl					KEGG_REACTION:R05623|UM-BBD_reactionID:r1407|RHEA:31979|EC:1.14.13.148									molecular_function											owl:Class	
GO:1905207	biolink:NamedThing	regulation of cardiocyte differentiation	Any process that modulates the frequency, rate or extent of cardiocyte differentiation.	tmpzr1t_l9r_go_relaxed.owl	regulation of heart cell differentiation|regulation of cardiac cell differentiation							bc	2016-06-02T07:20:01Z					biological_process											owl:Class	
GO:0005456	biolink:NamedThing	CMP-N-acetylneuraminate transmembrane transporter activity	Enables the transfer of a CMP-N-acetylneuraminate from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	CMP-sialic acid transmembrane transporter activity				Reactome:R-HSA-5651942|Reactome:R-HSA-727807									molecular_function											owl:Class	
GO:0003263	biolink:NamedThing	cardioblast proliferation	The multiplication or reproduction of cardioblasts, resulting in the expansion of the population in the heart field. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-10-15T02:13:05Z					biological_process											owl:Class	
GO:0032566	biolink:NamedThing	dGDP binding	Binding to dGDP, deoxyguanosine diphosphate.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0009557	biolink:NamedThing	antipodal cell differentiation	The process in which an uncellularized nucleus cellularizes and acquires the specialized features of an antipodal cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0048402	biolink:NamedThing	intermediate mesoderm structural organization	The process that contributes to the act of creating the structural organization of the intermediate mesoderm. This process pertains to the physical shaping of a rudimentary structure.	tmpzr1t_l9r_go_relaxed.owl	intermediate mesoderm structural organisation													biological_process											owl:Class	
GO:0048338	biolink:NamedThing	mesoderm structural organization	The process that contributes to the act of creating the structural organization of the mesoderm. This process pertains to the physical shaping of a rudimentary structure.	tmpzr1t_l9r_go_relaxed.owl	mesoderm structural organisation													biological_process											owl:Class	
GO:0046279	biolink:NamedThing	3,4-dihydroxybenzoate biosynthetic process	The chemical reactions and pathways resulting in the formation of 3,4-dihydroxybenzoate.	tmpzr1t_l9r_go_relaxed.owl	protocatechuate synthesis|protocatechuate formation|protocatechuate biosynthesis|protocatechuate biosynthetic process|protocatechuate anabolism													biological_process											owl:Class	
GO:0051758	biolink:NamedThing	homologous chromosome movement towards spindle pole in meiosis I anaphase	The directed movement of homologous chromosomes from the center of the spindle towards the spindle poles, mediated by the shortening of microtubules attached to the chromosomes, during meiosis I anaphase.	tmpzr1t_l9r_go_relaxed.owl	homologous chromosome movement towards spindle pole during meiosis I|meiosis I, homologous chromosome movement towards spindle pole													biological_process											owl:Class	
GO:0033861	biolink:NamedThing	negative regulation of NAD(P)H oxidase activity	Any process that stops or reduces the activity of the enzyme NAD(P)H oxidase.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of NAD(P)H oxidase activity|down regulation of NAD(P)H oxidase activity|downregulation of NAD(P)H oxidase activity|inhibition of NAD(P)H oxidase activity													biological_process											owl:Class	
GO:1990654	biolink:NamedThing	sebum secreting cell proliferation	The multiplication or reproduction of sebocytes by cell division, resulting in the expansion of their population. A sebocyte is an epithelial cell that makes up the sebaceous glands, and secrete sebum.	tmpzr1t_l9r_go_relaxed.owl	sebocyte proliferation							hjd	2015-02-23T19:43:49Z					biological_process											owl:Class	
GO:1900326	biolink:NamedThing	positive regulation of maltotriulose transport	Any process that activates or increases the frequency, rate or extent of maltotriulose transport.	tmpzr1t_l9r_go_relaxed.owl	activation of maltotriulose transport|up-regulation of maltotriulose transport|up regulation of maltotriulose transport|upregulation of maltotriulose transport							tt	2012-04-06T01:48:25Z					biological_process											owl:Class	
GO:0042970	biolink:NamedThing	homoserine transmembrane transporter activity	Enables the transfer of homoserine from one side of a membrane to the other. Homoserine is alpha-amino-gamma-hydroxybutyric acid, an intermediate in the biosynthesis of cystathionine, threonine and methionine.	tmpzr1t_l9r_go_relaxed.owl	homoserine transporter activity													molecular_function											owl:Class	
GO:0050132	biolink:NamedThing	N-methylalanine dehydrogenase activity	Catalysis of the reaction: N-methyl-L-alanine + H(2)O + NADP(+) = H(+) + methylammonium + NADPH + pyruvate.	tmpzr1t_l9r_go_relaxed.owl	N-methyl-L-alanine:NADP+ oxidoreductase (demethylating, deaminating)				MetaCyc:N-METHYLALANINE-DEHYDROGENASE-RXN|RHEA:21768|KEGG_REACTION:R01584|EC:1.4.1.17									molecular_function											owl:Class	
GO:0045855	biolink:NamedThing	negative regulation of pole plasm oskar mRNA localization	Any process that stops, prevents, or reduces the frequency, rate or extent of a process in which oskar mRNA is transported to, or maintained in, the oocyte pole plasm.	tmpzr1t_l9r_go_relaxed.owl	inhibition of pole plasm oskar mRNA localization|down-regulation of pole plasm oskar mRNA localization|downregulation of pole plasm oskar mRNA localization|down regulation of pole plasm oskar mRNA localization|negative regulation of pole plasm oskar mRNA localisation|negative regulation of oocyte pole plasm oskar mRNA localization													biological_process											owl:Class	
GO:0072763	biolink:NamedThing	cellular response to hesperadin	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hesperadin stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2012-11-09T11:50:58Z					biological_process											owl:Class	
GO:1990786	biolink:NamedThing	cellular response to dsDNA	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a double-stranded DNA stimulus.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-06-24T22:48:25Z					biological_process											owl:Class	
GO:0051949	biolink:NamedThing	negative regulation of gamma-aminobutyric acid uptake involved in transmission of nerve impulse	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of gamma-aminobutyric acid (GABA, 4-aminobutyrate) into a neuron or glial cell.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of GABA reuptake|inhibition of gamma-aminobutyric acid uptake during transmission of nerve impulse|negative regulation of 4-aminobutyrate reuptake|negative regulation of GABA uptake during transmission of nerve impulse|negative regulation of gamma-aminobutyric acid uptake involved in conduction of nerve impulse|negative regulation of gamma-aminobutyric acid uptake during transmission of nerve impulse|downregulation of gamma-aminobutyric acid uptake during transmission of nerve impulse|down-regulation of gamma-aminobutyric acid uptake during transmission of nerve impulse|down regulation of gamma-aminobutyric acid uptake during transmission of nerve impulse|negative regulation of gamma-aminobutyric acid reuptake|negative regulation of 4-aminobutyrate uptake during transmission of nerve impulse													biological_process											owl:Class	
GO:0102502	biolink:NamedThing	ADP-glucose-starch glucosyltransferase activity	Catalysis of the reaction: ADP alpha-D-glucoside + n a 1,4-alpha-D-glucan = ADP + n alpha-amylose.	tmpzr1t_l9r_go_relaxed.owl					EC:2.4.1.242|MetaCyc:RXN-14378									molecular_function											owl:Class	
GO:0033840	biolink:NamedThing	NDP-glucose-starch glucosyltransferase activity	Catalysis of the reaction: NDP-glucose + (1,4-alpha-D-glucosyl)n = NDP + (1,4-alpha-D-glucosyl)n+1.	tmpzr1t_l9r_go_relaxed.owl	starch synthase II activity|granule-bound starch synthase I activity|granule-bound starch synthase II activity|GBSSI|GBSSII|waxy protein|GBSS|NDP-glucose:1,4-alpha-D-glucan 4-alpha-D-glucosyltransferase activity|NDPglucose-starch glucosyltransferase activity|starch granule-bound nucleoside diphosphate glucose-starch glucosyltransferase activity|granule-bound starch synthase activity				RHEA:15873|MetaCyc:2.4.1.242-RXN|EC:2.4.1.242									molecular_function											owl:Class	
GO:0010357	biolink:NamedThing	homogentisate solanesyltransferase activity	Catalysis of the reaction: homogentisic acid + all-trans-nonaprenyl diphosphate + 3 H+ = 2-methyl-6-solanyl-1,4-benzoquinonone + CO2 + diphosphate. 2-methyl-6-solanyl-1,4-benzoquinonone is also known as 2-methyl-6-solanesylplastoquinol and all-trans-nonaprenyl diphosphate as solanesyl diphosphate.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1904832	biolink:NamedThing	negative regulation of removal of superoxide radicals	Any process that stops, prevents or reduces the frequency, rate or extent of removal of superoxide radicals.	tmpzr1t_l9r_go_relaxed.owl	inhibition of removal of superoxide radicals|inhibition of removal of oxygen free radicals|downregulation of removal of O2-|downregulation of removal of superoxide radicals|negative regulation of removal of oxygen free radicals|inhibition of cellular detoxification of superoxide radicals|down regulation of cellular detoxification of superoxide radicals|down-regulation of removal of superoxide radicals|down regulation of removal of superoxide radicals|downregulation of removal of oxygen free radicals|downregulation of cellular detoxification of superoxide radicals|down-regulation of removal of oxygen free radicals|negative regulation of removal of O2-|down-regulation of cellular detoxification of superoxide radicals|inhibition of removal of O2-|down regulation of removal of oxygen free radicals|negative regulation of cellular detoxification of superoxide radicals|down regulation of removal of O2-|down-regulation of removal of O2-							rph	2015-11-24T15:30:18Z					biological_process											owl:Class	
GO:1901410	biolink:NamedThing	regulation of tetrapyrrole biosynthetic process from glutamate	Any process that modulates the frequency, rate or extent of tetrapyrrole biosynthetic process from glutamate.	tmpzr1t_l9r_go_relaxed.owl	regulation of tetrapyrrole formation from glutamate|regulation of tetrapyrrole biosynthesis from glutamate|regulation of tetrapyrrole anabolism from glutamate|regulation of tetrapyrrole synthesis from glutamate							tt	2012-10-01T16:20:56Z					biological_process											owl:Class	
GO:2001022	biolink:NamedThing	positive regulation of response to DNA damage stimulus	Any process that activates or increases the frequency, rate or extent of response to DNA damage stimulus.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of response to genotoxic stress|positive regulation of cellular response to DNA damage stimulus|positive regulation of cellular DNA damage response|positive regulation of DNA damage response							yaf	2011-08-19T10:20:33Z					biological_process											owl:Class	
GO:1903118	biolink:NamedThing	urate homeostasis	Any process involved in the maintenance of an internal steady state of urate within an organism or cell.	tmpzr1t_l9r_go_relaxed.owl								dph	2014-06-13T14:54:51Z					biological_process											owl:Class	
GO:0140221	biolink:NamedThing	pathogen-containing vacuole membrane	Host-derived membrane of a pathogen-containing vacuole.	tmpzr1t_l9r_go_relaxed.owl	pathogen inclusion membrane|pathogen-containing compartment membrane	https://github.com/geneontology/go-ontology/issues/15580						pg	2018-04-20T06:18:25Z					cellular_component											owl:Class	
GO:0034981	biolink:NamedThing	FHL3-CREB complex	A protein complex that contains CREB and FHL3, and is involved in transcriptional regulation.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0047673	biolink:NamedThing	anthranilate N-malonyltransferase activity	Catalysis of the reaction: anthranilate + malonyl-CoA = N-malonylanthranilate + CoA.	tmpzr1t_l9r_go_relaxed.owl	malonyl-CoA:anthranilate N-malonyltransferase activity				KEGG_REACTION:R00989|EC:2.3.1.113|MetaCyc:ANTHRANILATE-N-MALONYLTRANSFERASE-RXN|RHEA:17557									molecular_function											owl:Class	
GO:0050735	biolink:NamedThing	N-malonyltransferase activity	Catalysis of the transfer of a malonyl group to a nitrogen atom on the acceptor molecule.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0007616	biolink:NamedThing	long-term memory	The memory process that deals with the storage, retrieval and modification of information a long time (typically weeks, months or years) after receiving that information. This type of memory is typically dependent on gene transcription regulated by second messenger activation.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Long-term_memory									biological_process											owl:Class	
GO:0007613	biolink:NamedThing	memory	The activities involved in the mental information processing system that receives (registers), modifies, stores, and retrieves informational stimuli. The main stages involved in the formation and retrieval of memory are encoding (processing of received information by acquisition), storage (building a permanent record of received information as a result of consolidation) and retrieval (calling back the stored information and use it in a suitable way to execute a given task).	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Memory									biological_process											owl:Class	
GO:0051668	biolink:NamedThing	localization within membrane	Any process in which a substance or cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in, a specific location within a membrane.	tmpzr1t_l9r_go_relaxed.owl	localisation within membrane|establishment and maintenance of localization in membrane|positioning within membrane|localization to membrane|establishment and maintenance of position in membrane													biological_process											owl:Class	
GO:0061871	biolink:NamedThing	negative regulation of hepatic stellate cell migration	Any process that stops, prevents or reduces the frequency, rate or extent of hepatic stellate cell migration.	tmpzr1t_l9r_go_relaxed.owl								dph	2017-05-01T13:20:51Z					biological_process											owl:Class	
GO:0060762	biolink:NamedThing	regulation of branching involved in mammary gland duct morphogenesis	Any process that modulates the rate, frequency, or extent of branching involved in mammary gland duct morphogenesis.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-06-22T05:20:33Z					biological_process											owl:Class	
GO:0090377	biolink:NamedThing	seed trichome initiation	The process in which the developmental fate of an epidermal cell becomes restricted such that it will develop into a seed trichome, causing a change in the orientation of cell division in the ovule epidermis at or just before anthesis.	tmpzr1t_l9r_go_relaxed.owl	seed trichome fate commitment					These processes continue up to 3 days post-anthesis (DPA) in Gossypium spp.		tb	2010-09-15T02:13:59Z					biological_process											owl:Class	
GO:1901397	biolink:NamedThing	positive regulation of transforming growth factor beta2 activation	Any process that activates or increases the frequency, rate or extent of transforming growth factor beta2 activation.	tmpzr1t_l9r_go_relaxed.owl	upregulation of TGF-beta 2 activation|up-regulation of TGF-beta 2 activation|up regulation of TGF-beta 2 activation|activation of transforming growth factor beta2 activation|upregulation of transforming growth factor beta2 activation|activation of TGFbeta 2 activation|positive regulation of TGFB2 activation|up-regulation of TGFB2 activation|upregulation of TGFbeta 2 activation|activation of TGFB2 activation|up-regulation of transforming growth factor beta2 activation|up-regulation of TGFbeta 2 activation|positive regulation of TGFbeta 2 activation|up regulation of transforming growth factor beta2 activation|up regulation of TGFbeta 2 activation|upregulation of TGFB2 activation|activation of TGF-beta 2 activation|positive regulation of TGF-beta 2 activation|up regulation of TGFB2 activation							bf	2012-10-01T10:48:15Z					biological_process											owl:Class	
GO:1903557	biolink:NamedThing	positive regulation of tumor necrosis factor superfamily cytokine production	Any process that activates or increases the frequency, rate or extent of tumor necrosis factor superfamily cytokine production.	tmpzr1t_l9r_go_relaxed.owl	up regulation of tumor necrosis factor superfamily cytokine production|up-regulation of tumor necrosis factor superfamily cytokine production|activation of TNFSF cytokine production|up-regulation of TNFSF cytokine production|activation of TNF superfamily production|upregulation of tumor necrosis factor superfamily cytokine production|positive regulation of TNF superfamily production|upregulation of TNF superfamily production|up-regulation of TNF superfamily production|upregulation of TNFSF cytokine production|up regulation of TNFSF cytokine production|positive regulation of TNFSF cytokine production|activation of tumor necrosis factor superfamily cytokine production|up regulation of TNF superfamily production							pga	2014-10-21T10:26:23Z					biological_process											owl:Class	
GO:0061179	biolink:NamedThing	negative regulation of insulin secretion involved in cellular response to glucose stimulus	Any process that decreases the frequency, rate or extent of the regulated release of insulin that contributes to the response of a cell to glucose.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of insulin secretion involved in cellular response to glucose|negative regulation of insulin secretion in response to glucose							dph	2010-07-13T09:41:46Z					biological_process											owl:Class	
GO:0032877	biolink:NamedThing	positive regulation of DNA endoreduplication	Any process that activates or increases the frequency, rate or extent of DNA endoreduplication.	tmpzr1t_l9r_go_relaxed.owl	up regulation of DNA endoreduplication|upregulation of DNA endoreduplication|activation of DNA endoreduplication|up-regulation of DNA endoreduplication|positive regulation of DNA re-duplication|positive regulation of DNA endoreplication|stimulation of DNA endoreduplication													biological_process											owl:Class	
GO:0001931	biolink:NamedThing	uropod	A membrane projection with related cytoskeletal components at the trailing edge of a cell in the process of migrating or being activated, found on the opposite side of the cell from the leading edge or immunological synapse, respectively.	tmpzr1t_l9r_go_relaxed.owl	retractile pole|distal pole complex|uropodium													cellular_component											owl:Class	
GO:1905220	biolink:NamedThing	negative regulation of platelet formation	Any process that stops, prevents or reduces the frequency, rate or extent of platelet formation.	tmpzr1t_l9r_go_relaxed.owl	downregulation of platelet formation|down regulation of platelet extrusion|inhibition of platelet extrusion|downregulation of platelet extrusion|inhibition of platelet formation|down-regulation of platelet extrusion|down regulation of platelet formation|down-regulation of platelet formation|negative regulation of platelet extrusion							sl	2016-06-06T22:15:54Z					biological_process											owl:Class	
GO:0047831	biolink:NamedThing	D-ornithine 4,5-aminomutase activity	Catalysis of the reaction: D-ornithine = (2R,4S)-2,4-diaminopentanoate.	tmpzr1t_l9r_go_relaxed.owl	D-alpha-ornithine 5,4-aminomutase activity|D-ornithine aminomutase activity				EC:5.4.3.5|KEGG_REACTION:R02461|RHEA:14893|MetaCyc:ORNMUTST-RXN									molecular_function											owl:Class	
GO:0062237	biolink:NamedThing	protein localization to postsynapse	Any process in which a protein is transported to, and/or maintained at the postsynapse, the part of a synapse that is part of the post-synaptic cell.	tmpzr1t_l9r_go_relaxed.owl								dph	2020-04-20T13:58:43Z					biological_process											owl:Class	
GO:0035418	biolink:NamedThing	protein localization to synapse	Any process in which a protein is transported to, and/or maintained at the synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell.	tmpzr1t_l9r_go_relaxed.owl	protein localisation to synapse							bf	2010-03-29T10:58:53Z					biological_process											owl:Class	
GO:0098687	biolink:NamedThing	chromosomal region	Any subdivision of a chromosome along its length.	tmpzr1t_l9r_go_relaxed.owl	chromosome region					Chromosomal regions include parts that are not part of the chromatin.  Examples include the kinetochore.								cellular_component											owl:Class	
GO:0047963	biolink:NamedThing	glycine N-choloyltransferase activity	Catalysis of the reaction: choloyl-CoA + glycine = CoA + glycocholate.	tmpzr1t_l9r_go_relaxed.owl	cholyl-CoA glycine-taurine N-acyltransferase activity|cholyl-CoA:taurine N-acyltransferase activity|choloyl-CoA:glycine N-choloyltransferase activity|bile acid-CoA:amino acid N-acyltransferase activity|amino acid N-choloyltransferase activity|BAT activity|glycine--taurine N-acyltransferase activity|BACAT activity				RHEA:14001|MetaCyc:GLYCINE-N-CHOLOYLTRANSFERASE-RXN|EC:2.3.1.65									molecular_function											owl:Class	
GO:0052615	biolink:NamedThing	ent-kaurene oxidase activity	Catalysis of the reaction: H+ + NADPH + ent-kaur-16-ene + oxygen = H2O + NADP+ + ent-kaur-16-en-19-ol.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:1.14.13.78-RXN|RHEA:32323|EC:1.14.14.86									molecular_function											owl:Class	
GO:0102840	biolink:NamedThing	1-18:2-2-16:3-monogalactosyldiacylglycerol desaturase activity	Catalysis of the reaction: 1-18:2-2-16:3-monogalactosyldiacylglycerol + O2 + a reduced electron acceptor <=> 1-18:3-2-16:3-monogalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-8301|EC:1.14.19.35									molecular_function											owl:Class	
GO:0007158	biolink:NamedThing	neuron cell-cell adhesion	The attachment of a neuron to another cell via adhesion molecules.	tmpzr1t_l9r_go_relaxed.owl	neuron adhesion|neuronal cell adhesion													biological_process											owl:Class	
GO:0006186	biolink:NamedThing	dGDP phosphorylation	The process of introducing a phosphate group into dGDP, deoxyguanosine diphosphate, to produce dGTP.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0009216	biolink:NamedThing	purine deoxyribonucleoside triphosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of purine deoxyribonucleoside triphosphate, a compound consisting of a purine base linked to a deoxyribose sugar esterified with triphosphate on the sugar.	tmpzr1t_l9r_go_relaxed.owl	purine deoxyribonucleoside triphosphate biosynthesis|purine deoxyribonucleoside triphosphate synthesis|purine deoxyribonucleoside triphosphate formation|purine deoxyribonucleoside triphosphate anabolism													biological_process											owl:Class	
GO:0006864	biolink:NamedThing	pyrimidine nucleotide transport	The directed movement of a pyrimidine nucleotide, any compound consisting of a pyrimidine nucleoside esterified with (ortho)phosphate, into, out of or within a cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0032104	biolink:NamedThing	regulation of response to extracellular stimulus	Any process that modulates the frequency, rate or extent of a response to an extracellular stimulus.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0120325	biolink:NamedThing	NuRD complex binding	Binding to a NuRD complex.	tmpzr1t_l9r_go_relaxed.owl								krc	2021-08-03T21:15:31Z					molecular_function											owl:Class	
GO:0032389	biolink:NamedThing	MutLalpha complex	A heterodimer involved in the recognition of base-base and small insertion/deletion mismatches. In human the complex consists of two subunits, MLH1 and PMS2.	tmpzr1t_l9r_go_relaxed.owl	MLH1/PMS2 complex|MutL-alpha complex|MMR complex													cellular_component											owl:Class	
GO:0036490	biolink:NamedThing	regulation of translation in response to endoplasmic reticulum stress	Modulation of the frequency, rate or extent of translation as a result of endoplasmic reticulum stress.	tmpzr1t_l9r_go_relaxed.owl	regulation of translation in response to ER stress							bf	2015-02-05T09:50:11Z					biological_process											owl:Class	
GO:0052164	biolink:NamedThing	symbiont defense to host-produced reactive oxygen species	Any process in which a symbiont modulates the frequency, rate or extent of the production of reactive oxygen species as part of the defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	modulation by organism of defense-related host oxidative burst|modulation by organism of defense-related host reactive oxidative species production|evasion or tolerance of host-produced ROIs|evasion or tolerance by symbiont of reactive oxygen species produced by other organism involved in symbiotic interaction|evasion or tolerance of host-produced AOS|evasion or tolerance by organism of reactive oxygen species produced by other organism involved in symbiotic interaction|evasion or tolerance of host-produced reactive oxygen intermediates|response to defense-related host reactive oxygen species production|modulation by organism of defense-related reactive oxygen species production in other organism involved in symbiotic interaction|modulation by organism of defense-related host active oxygen species production|evasion or tolerance of defense-related host respiratory burst|evasion by symbiont of cellular damage caused by host oxidative burst|response to defense-related reactive oxygen species production by other organism involved in symbiotic interaction|modulation by symbiont of defense-related host reactive oxygen species production|evasion or tolerance by organism of host-produced reactive oxygen species|evasion or tolerance of host-produced active oxygen species|modulation by organism of defense-related host ROI production|modulation by organism of defense-related host AOS production|modulation by organism of defense-related host ROS production|evasion or tolerance of host-produced ROS|modulation by organism of defense-related host metabolic burst|modulation by organism of defense-related host respiratory burst|evasion or tolerance of defense-related host oxidative burst|evasion or tolerance of reactive oxygen species produced by host|modulation by organism of defense-related host reactive oxygen intermediate production|evasion or tolerance of defense-related host metabolic burst|evasion or tolerance by organism of reactive oxygen species produced during host defense response|evasion or tolerance by symbiont of host-produced reactive oxygen species	https://github.com/geneontology/go-ontology/issues/18697										GO:0052567|GO:0052550|GO:0052303|GO:0052385|GO:0052059		biological_process											owl:Class	
GO:0042783	biolink:NamedThing	evasion of host immune response	A process by which an organism avoids the effects of the host organism's immune response. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	evasion or tolerance of host immune response|active evasion of host immune response|mitigation of host immune response|active immune evasion|passive evasion of host immune response|immune evasion|passive immune evasion|passive evasion of immune response of other organism involved in symbiotic interaction|active evasion of immune response of other organism involved in symbiotic interaction	https://github.com/geneontology/go-ontology/issues/17894|https://github.com/geneontology/go-ontology/issues/18357										GO:0051805|GO:0051810|GO:0051809|GO:0020012|GO:0042782		biological_process											owl:Class	
GO:0075209	biolink:NamedThing	induction by symbiont of host cAMP-mediated signal transduction	Any process in which the symbiont activates, maintains or increases the frequency, rate or extent of cAMP-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	positive regulation by symbiont of host cAMP-mediated signal transduction|positive regulation by symbiont of host cAMP-mediated signaling					Note that this term is used to annotate gene products of the symbiont. To annotate host gene products, consider the biological process term "positive regulation by host of symbiont cAMP-mediated signal transduction ; GO:0075206".								biological_process											owl:Class	
GO:0075208	biolink:NamedThing	modulation by symbiont of host cAMP-mediated signal transduction	Any process in which the symbiont modulates the frequency, rate or extent of cAMP-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	modulation by symbiont of host cAMP-mediated signaling					Note that this term is used to annotate gene products of the symbiont. To annotate host gene products, consider the biological process term "modulation by host of symbiont cAMP-mediated signal transduction ; GO:0075205".								biological_process											owl:Class	
GO:0003998	biolink:NamedThing	acylphosphatase activity	Catalysis of the reaction: an acyl phosphate + H2O = a carboxylate + phosphate.	tmpzr1t_l9r_go_relaxed.owl	acetylphosphatase activity|acylphosphate phosphohydrolase activity|Ho 1-3|acetic phosphatase activity|GP 1-3|1,3-diphosphoglycerate phosphatase activity				EC:3.6.1.7|RHEA:14965|MetaCyc:ACYLPHOSPHATASE-RXN									molecular_function											owl:Class	
GO:0002846	biolink:NamedThing	regulation of T cell tolerance induction to tumor cell	Any process that modulates the frequency, rate, or extent of T cell tolerance induction to tumor cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0046456	biolink:NamedThing	icosanoid biosynthetic process	The chemical reactions and pathways resulting in the formation of icosanoids, any of a group of C20 polyunsaturated fatty acids.	tmpzr1t_l9r_go_relaxed.owl	icosanoid synthesis|eoxin biosynthesis|eicosanoid biosynthetic process|eicosanoid biosynthesis|icosanoid formation|eoxin synthesis|icosanoid biosynthesis|icosanoid anabolism	https://github.com/geneontology/go-ontology/issues/18848			Wikipedia:Eicosanoid									biological_process											owl:Class	
GO:0006690	biolink:NamedThing	icosanoid metabolic process	The chemical reactions and pathways involving icosanoids, any of a group of C20 polyunsaturated fatty acids.	tmpzr1t_l9r_go_relaxed.owl	icosanoid metabolism|eicosanoid metabolism|eicosanoid metabolic process													biological_process											owl:Class	
GO:1903117	biolink:NamedThing	regulation of actin filament organization involved in cytokinetic actomyosin contractile ring assembly	Any process that modulates the frequency, rate or extent of actin filament organization involved in cytokinetic actomyosin contractile ring assembly.	tmpzr1t_l9r_go_relaxed.owl	regulation of actin filament organization of contractile ring assembly|regulation of actin filament organisation of cytokinesis, actomyosin contractile ring formation|regulation of actin filament organisation of constriction ring assembly|regulation of actin filament organisation of cytokinesis, actomyosin ring formation|regulation of regulation of actin filament localization of contractile ring assembly|regulation of regulation of actin filament localization of constriction ring assembly|regulation of actin filament organization of cytokinesis, actomyosin ring formation|regulation of actin filament organization of constriction ring assembly|regulation of regulation of actin filament localization of cytokinesis, contractile ring assembly|regulation of regulation of actin filament localization of cytokinesis, actomyosin contractile ring assembly|regulation of actin filament organisation of cytokinesis, contractile ring assembly|regulation of actin filament organization of cytokinesis, actomyosin ring biosynthesis|regulation of actin filament organisation of contractile ring assembly|regulation of actin filament organization of cytokinesis, contractile ring assembly|regulation of actin filament organisation of cytokinesis, actomyosin ring biosynthesis|regulation of regulation of actin filament localization of cytokinesis, actomyosin contractile ring formation|regulation of actin filament organisation of cytokinesis, actomyosin contractile ring assembly|regulation of regulation of actin filament localization of cytokinesis, actomyosin ring formation|regulation of regulation of actin filament localization of cytokinesis, actomyosin ring biosynthesis|regulation of actin filament organization of cytokinesis, actomyosin contractile ring formation|regulation of actin filament organization of cytokinesis, actomyosin contractile ring assembly							al	2014-06-12T16:57:17Z					biological_process											owl:Class	
GO:0044781	biolink:NamedThing	bacterial-type flagellum organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a bacterial-type flagellum, a motor complex composed of an extracellular helical protein filament coupled to a rotary motor embedded in the cell envelope which functions in cell motility.	tmpzr1t_l9r_go_relaxed.owl								jl	2013-03-27T15:07:00Z					biological_process											owl:Class	
GO:0015882	biolink:NamedThing	L-ascorbic acid transmembrane transport	The process in which L-ascorbic acid is transported across a lipid bilayer, from one side of a membrane to the other. L-ascorbate, (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate, is vitamin C and has co-factor and anti-oxidant activities in many species.	tmpzr1t_l9r_go_relaxed.owl	L-ascorbate transport|L-ascorbic acid transport|vitamin C transport													biological_process											owl:Class	
GO:0035860	biolink:NamedThing	glial cell-derived neurotrophic factor receptor signaling pathway	The series of molecular signals generated as a consequence of a glial cell-derived neurotrophic factor receptor binding to one of its physiological ligands.	tmpzr1t_l9r_go_relaxed.owl	glial cell derived neurotrophic factor receptor signaling pathway|GDNF receptor signaling pathway|glial cell-derived neurotrophic factor receptor signalling pathway|glial cell line-derived neurotrophic factor receptor signalling pathway							bf	2011-05-17T11:01:33Z					biological_process											owl:Class	
GO:0032129	biolink:NamedThing	histone deacetylase activity (H3-K9 specific)	Catalysis of the reaction: histone H3 N6-acetyl-L-lysine (position 9) + H2O = histone H3 L-lysine (position 9) + acetate. This reaction represents the removal of an acetyl group from lysine at position 9 of the histone H3 protein.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0046716	biolink:NamedThing	muscle cell cellular homeostasis	The cellular homeostatic process that preserves a muscle cell in a stable functional or structural state.	tmpzr1t_l9r_go_relaxed.owl	muscle homeostasis|muscle fiber maintenance													biological_process											owl:Class	
GO:0019001	biolink:NamedThing	guanyl nucleotide binding	Binding to a guanyl nucleotide, consisting of guanosine esterified with (ortho)phosphate.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-156909									molecular_function											owl:Class	
GO:0048601	biolink:NamedThing	oocyte morphogenesis	The process in which the structures of an oocyte are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of an oocyte.	tmpzr1t_l9r_go_relaxed.owl	oocyte morphogenesis during differentiation													biological_process											owl:Class	
GO:0001046	biolink:NamedThing	core promoter sequence-specific DNA binding	Binding to a sequence of DNA that is part of a core promoter region. The core promoter is composed of the transcription start site and binding sites for the RNA polymerase and the basal transcription machinery. The transcribed region might be described as a gene, cistron, or operon.	tmpzr1t_l9r_go_relaxed.owl	eubacterial-type RNA polymerase core promoter sequence-specific DNA binding|core promoter binding|bacterial-type RNA polymerase core promoter sequence-specific DNA binding	https://github.com/geneontology/go-ontology/issues/19312						krc	2010-08-25T04:17:44Z			GO:0001047|GO:0000985		molecular_function											owl:Class	
GO:0035769	biolink:NamedThing	B cell chemotaxis across high endothelial venule	The movement of a B cell to cross a high endothelial venule in response to an external stimulus.	tmpzr1t_l9r_go_relaxed.owl	B-cell chemotaxis across high endothelial venule							bf	2011-04-01T10:48:59Z					biological_process											owl:Class	
GO:0002518	biolink:NamedThing	lymphocyte chemotaxis across high endothelial venule	The movement of a lymphocyte to cross a high endothelial venule in response to an external stimulus.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0070730	biolink:NamedThing	cAMP transport	The directed movement of cyclic AMP (cAMP), into, out of or within a cell.	tmpzr1t_l9r_go_relaxed.owl	cyclic AMP transport							mah	2009-06-17T03:53:45Z					biological_process											owl:Class	
GO:0021925	biolink:NamedThing	cerebellar Purkinje cell precursor proliferation	The multiplication or reproduction of neuroblasts that will give rise to Purkinje cells. A Purkinje cell is an inhibitory GABAergic neuron found in the cerebellar cortex that projects to the deep cerebellar nuclei and brain stem.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0062203	biolink:NamedThing	Viteagnusin D synthase activity	Catalysis of the reaction: H2O + peregrinol diphosphate = diphosphate + viteagnusin D.	tmpzr1t_l9r_go_relaxed.owl					RHEA:62180			dph	2020-01-02T18:25:47Z					molecular_function											owl:Class	
GO:0120258	biolink:NamedThing	peptidyl-threonine O-acetylation	The acetylation of peptidyl-threonine to form peptidyl-O-acetyl-L-threonine.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/19957			RESID:AA0364			krc	2020-09-08T18:07:44Z					biological_process											owl:Class	
GO:0043978	biolink:NamedThing	histone H2A-K9 acetylation	The modification of histone H2A by the addition of an acetyl group to a lysine residue at position 9 of the histone.	tmpzr1t_l9r_go_relaxed.owl	histone H2A acetylation at K9													biological_process											owl:Class	
GO:0035912	biolink:NamedThing	dorsal aorta morphogenesis	The process in which the anatomical structures of the dorsal aorta are generated and organized. The dorsal aorta is a blood vessel in a single-pass circulatory system that carries oxygenated blood from the gills to the rest of the body. In a single-pass circulatory system blood passes once through the heart to supply the body once.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-06-24T11:22:14Z					biological_process											owl:Class	
GO:0035909	biolink:NamedThing	aorta morphogenesis	The process in which the anatomical structures of an aorta are generated and organized. An aorta is an artery that carries blood from the heart to other parts of the body.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-06-24T11:11:11Z					biological_process											owl:Class	
GO:0010885	biolink:NamedThing	regulation of cholesterol storage	Any process that modulates the rate or extent of cholesterol storage. Cholesterol storage is the accumulation and maintenance in cells or tissues of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0032719	biolink:NamedThing	negative regulation of TRAIL production	Any process that stops, prevents, or reduces the frequency, rate, or extent of TRAIL production.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of TRAIL biosynthetic process|down-regulation of TRAIL production|inhibition of TRAIL production|down regulation of TRAIL production|downregulation of TRAIL production											GO:0045555		biological_process											owl:Class	
GO:0045696	biolink:NamedThing	positive regulation of embryo sac egg cell differentiation	Any process that activates or increases the frequency, rate or extent of embryo sac egg cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	upregulation of female gametophyte egg cell differentiation|activation of female gametophyte egg cell differentiation|stimulation of female gametophyte egg cell differentiation|up regulation of female gametophyte egg cell differentiation|up-regulation of female gametophyte egg cell differentiation|positive regulation of female gametophyte egg cell differentiation													biological_process											owl:Class	
GO:0033135	biolink:NamedThing	regulation of peptidyl-serine phosphorylation	Any process that modulates the frequency, rate or extent of the phosphorylation of peptidyl-serine.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0043491	biolink:NamedThing	protein kinase B signaling	A series of reactions, mediated by the intracellular serine/threonine kinase protein kinase B (also called AKT), which occurs as a result of a single trigger reaction or compound.	tmpzr1t_l9r_go_relaxed.owl	PKB signaling cascade|PKB signalling cascade|AKT signaling|AKT signalling cascade|PKB signal transduction|protein kinase B signaling cascade|AKT signal transduction|protein kinase B signalling cascade|PKB signaling|AKT signaling cascade|protein kinase B signal transduction													biological_process											owl:Class	
GO:0050942	biolink:NamedThing	positive regulation of pigment cell differentiation	Any process that activates or increases the frequency, rate or extent of pigment cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	activation of pigment cell differentiation|stimulation of pigment cell differentiation|upregulation of pigment cell differentiation|up regulation of pigment cell differentiation|up-regulation of pigment cell differentiation													biological_process											owl:Class	
GO:0035358	biolink:NamedThing	regulation of peroxisome proliferator activated receptor signaling pathway	Any process that modulates the frequency, rate or extent of the peroxisome proliferator activated receptor signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	regulation of PPAR signaling pathway|regulation of peroxisome proliferator-activated receptor signaling pathway|regulation of peroxisome proliferator activated receptor signalling pathway							bf	2010-03-05T10:39:37Z					biological_process											owl:Class	
GO:1903625	biolink:NamedThing	negative regulation of DNA catabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of DNA catabolic process.	tmpzr1t_l9r_go_relaxed.owl	inhibition of DNA breakdown|down regulation of DNA catabolism|down-regulation of DNA breakdown|down regulation of DNA catabolic process|negative regulation of DNA breakdown|downregulation of DNA catabolic process|down regulation of DNA degradation|downregulation of DNA degradation|inhibition of DNA catabolic process|down-regulation of DNA degradation|inhibition of DNA catabolism|negative regulation of DNA catabolism|down regulation of DNA breakdown|negative regulation of DNA degradation|inhibition of DNA degradation|down-regulation of DNA catabolic process|downregulation of DNA breakdown|down-regulation of DNA catabolism|downregulation of DNA catabolism							sl	2014-11-19T22:36:43Z					biological_process											owl:Class	
GO:0052160	biolink:NamedThing	modulation by symbiont of host systemic acquired resistance	Any process in which a symbiont modulates the frequency, rate or extent of systemic acquired resistance in the host organism; systemic acquired resistance is a salicylic acid-mediated response that confers broad spectrum systemic resistance. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	modulation by organism of systemic acquired resistance in other organism involved in symbiotic interaction|modulation by symbiont of systemic acquired resistance in host											GO:0052299		biological_process											owl:Class	
GO:0052553	biolink:NamedThing	modulation by symbiont of host immune response	Any process in which a symbiont modulates the frequency, rate or extent of the immune response of the host organism; the immune response is any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	modulation by organism of immune response of other organism involved in symbiotic interaction											GO:0052552		biological_process											owl:Class	
GO:0160006	biolink:NamedThing	Fc receptor-mediated immune complex endocytosis	An endocytosis process mediated by the Fc receptor for the purpose of delivery of antigen-bound immunoglobulin to an intracellular compartment where the antigen can be processed and loaded onto MHC molecules. This process selectively targets antigens for presentation by MHC class I or MHC class II.	tmpzr1t_l9r_go_relaxed.owl	Ig-complexed antigen endocytosis via Fc receptor|Fc receptor-mediated immune complex internalization|antigen-antibody immune complex uptake via Fc receptor							rynl	2021-11-05T23:38:29Z					biological_process											owl:Class	
GO:0150117	biolink:NamedThing	positive regulation of cell-substrate junction organization	Any process that activates or increases the frequency, rate or extent of cell-substrate junction organization.	tmpzr1t_l9r_go_relaxed.owl								bc	2019-11-14T12:15:07Z					biological_process											owl:Class	
GO:0150116	biolink:NamedThing	regulation of cell-substrate junction organization	Any process that modulates the frequency, rate or extent of cell-substrate junction organization.	tmpzr1t_l9r_go_relaxed.owl								bc	2019-11-14T12:12:27Z					biological_process											owl:Class	
GO:0042690	biolink:NamedThing	negative regulation of crystal cell differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of crystal cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	inhibition of crystal cell differentiation|down regulation of crystal cell differentiation|down-regulation of crystal cell differentiation|downregulation of crystal cell differentiation													biological_process											owl:Class	
GO:1990683	biolink:NamedThing	DNA double-strand break attachment to nuclear envelope	A process in which the DNA double-strand breaks are attached to the inner surface of the nuclear envelope proximal to the spindle pole body, or iMTOCs.	tmpzr1t_l9r_go_relaxed.owl								vw	2015-03-10T16:36:21Z					biological_process											owl:Class	
GO:1902048	biolink:NamedThing	neosartoricin metabolic process	The chemical reactions and pathways involving neosartoricin.	tmpzr1t_l9r_go_relaxed.owl	neosartoricin metabolism							di	2013-04-08T20:31:02Z					biological_process											owl:Class	
GO:1903175	biolink:NamedThing	fatty alcohol biosynthetic process	The chemical reactions and pathways resulting in the formation of fatty alcohol.	tmpzr1t_l9r_go_relaxed.owl	fatty alcohol anabolism|fatty alcohol synthesis|fatty alcohol formation|fatty alcohol biosynthesis							tt	2014-07-14T01:51:54Z					biological_process											owl:Class	
GO:2000429	biolink:NamedThing	negative regulation of neutrophil aggregation	Any process that stops, prevents or reduces the frequency, rate or extent of neutrophil aggregation.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of neutrophil leucocyte aggregation|negative regulation of neutrophilic leukocyte aggregation|negative regulation of neutrocyte aggregation							ebc	2011-02-28T05:19:28Z					biological_process											owl:Class	
GO:0046648	biolink:NamedThing	positive regulation of gamma-delta T cell proliferation	Any process that activates or increases the frequency, rate or extent of gamma-delta T cell proliferation.	tmpzr1t_l9r_go_relaxed.owl	upregulation of gamma-delta T cell proliferation|up regulation of gamma-delta T cell proliferation|activation of gamma-delta T cell proliferation|positive regulation of gamma-delta T-cell proliferation|stimulation of gamma-delta T cell proliferation|up-regulation of gamma-delta T cell proliferation|positive regulation of gamma-delta T lymphocyte proliferation|positive regulation of gamma-delta T-lymphocyte proliferation													biological_process											owl:Class	
GO:0033212	biolink:NamedThing	iron import into cell	The directed movement of iron ions from outside of a cell into the cytoplasmic compartment. This may occur via transport across the plasma membrane or via endocytosis.	tmpzr1t_l9r_go_relaxed.owl	ferrous ion import|iron assimilation|ferrous iron import|ferrous iron uptake							mah	2009-05-01T04:19:14Z			GO:0070627		biological_process											owl:Class	
GO:0044321	biolink:NamedThing	response to leptin	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leptin stimulus. Leptin is a hormone manufactured primarily in the adipocytes of white adipose tissue, and the level of circulating leptin is directly proportional to the total amount of fat in the body. It plays a key role in regulating energy intake and energy expenditure, including appetite and metabolism].	tmpzr1t_l9r_go_relaxed.owl	response to leptin stimulus							jl	2010-07-14T02:31:20Z					biological_process											owl:Class	
GO:0102700	biolink:NamedThing	alpha-thujene synthase activity	Catalysis of the reaction: geranyl diphosphate(3-) <=> alpha-thujene + diphosphoric acid.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-5105									molecular_function											owl:Class	
GO:1900781	biolink:NamedThing	fumiquinazoline C biosynthetic process	The chemical reactions and pathways resulting in the formation of fumiquinazoline C.	tmpzr1t_l9r_go_relaxed.owl	fumiquinazoline C anabolism|fumiquinazoline C formation|fumiquinazoline C synthesis|fumiquinazoline C biosynthesis							di	2012-06-04T09:30:58Z					biological_process											owl:Class	
GO:0032658	biolink:NamedThing	regulation of interleukin-15 production	Any process that modulates the frequency, rate, or extent of interleukin-15 production.	tmpzr1t_l9r_go_relaxed.owl	regulation of interleukin-15 biosynthetic process|regulation of IL-15 production											GO:0045372		biological_process											owl:Class	
GO:0022021	biolink:NamedThing	caudal ganglionic eminence cell proliferation	The multiplication or reproduction of caudal ganglionic eminence cells, resulting in the expansion of a cell population.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0022012	biolink:NamedThing	subpallium cell proliferation in forebrain	The multiplication or reproduction of subpallium cells in the forebrain, resulting in the expansion of a cell population.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0016697	biolink:NamedThing	oxidoreductase activity, acting on hydrogen as donor, cytochrome as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which hydrogen acts as an electron donor and reduces a cytochrome.	tmpzr1t_l9r_go_relaxed.owl					EC:1.12.2.-							GO:0016698		molecular_function											owl:Class	
GO:1901015	biolink:NamedThing	3alpha(S)-strictosidine biosynthetic process	The chemical reactions and pathways resulting in the formation of 3alpha(S)-strictosidine.	tmpzr1t_l9r_go_relaxed.owl	3alpha(S)-strictosidine synthesis|3alpha(S)-strictosidine formation|3alpha(S)-strictosidine biosynthesis|3alpha(S)-strictosidine anabolism							yaf	2012-06-15T10:47:26Z					biological_process											owl:Class	
GO:0031210	biolink:NamedThing	phosphatidylcholine binding	Binding to a phosphatidylcholine, a glycophospholipid in which a phosphatidyl group is esterified to the hydroxyl group of choline.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0033230	biolink:NamedThing	ABC-type cysteine transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + cysteine(out/in) = ADP + phosphate + cysteine(in/out).	tmpzr1t_l9r_go_relaxed.owl	cysteine-exporting ATPase activity|ATP-dependent cysteine transporter activity|cysteine-transporting ATPase activity|ATPase-coupled cysteine transporter activity|ATPase-coupled cysteine transmembrane transporter activity|cysteine exporter	https://github.com/geneontology/go-ontology/issues/17289										GO:0032519		molecular_function											owl:Class	
GO:0080033	biolink:NamedThing	response to nitrite	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrite stimulus.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0051460	biolink:NamedThing	negative regulation of corticotropin secretion	Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of corticotropic hormone from a cell.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of adrenocorticotropin secretion|negative regulation of ACTH secretion|down regulation of adrenocorticotropin secretion|negative regulation of corticotropic hormone secretion|negative regulation of adrenotropin secretion|downregulation of adrenocorticotropin secretion|inhibition of adrenocorticotropin secretion|negative regulation of adrenocorticotropic hormone secretion|negative regulation of adrenotropic hormone secretion|negative regulation of adrenocorticotropin secretion													biological_process											owl:Class	
GO:1905367	biolink:NamedThing	positive regulation of intralumenal vesicle formation	Any process that activates or increases the frequency, rate or extent of intralumenal vesicle formation.	tmpzr1t_l9r_go_relaxed.owl	activation of endosome membrane budding|upregulation of endosome membrane budding|up-regulation of intralumenal vesicle formation|upregulation of intralumenal vesicle formation|up regulation of endosome membrane budding|positive regulation of endosome membrane budding|up-regulation of endosome membrane budding|up regulation of intralumenal vesicle formation|activation of intralumenal vesicle formation							bc	2016-08-16T12:00:16Z					biological_process											owl:Class	
GO:0000773	biolink:NamedThing	phosphatidyl-N-methylethanolamine N-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + phosphatidyl-N-methylethanolamine = S-adenosyl-L-homocysteine + phosphatidyl-N-dimethylethanolamine.	tmpzr1t_l9r_go_relaxed.owl	phosphatidylethanolamine methyltransferase I|S-adenosyl-L-methionine:phosphatidyl-N-methylethanolamine N-methyltransferase activity|phosphatidyl-N-monomethylethanolamine methyltransferase activity|phosphatidylmonomethylethanolamine methyltransferase activity|phospholipid methyltransferase activity|phosphatidyl-N-methylethanolamine methyltransferase activity|PLMT|methyltransferase II				RHEA:32735|MetaCyc:2.1.1.71-RXN|EC:2.1.1.71									molecular_function											owl:Class	
GO:0001661	biolink:NamedThing	conditioned taste aversion	A conditioned aversion to a specific chemical compound as a result of that compound being coupled with a noxious stimulus.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Conditioned_taste_aversion|Wikipedia:Taste_aversion									biological_process											owl:Class	
GO:0008306	biolink:NamedThing	associative learning	Learning by associating a stimulus (the cause) with a particular outcome (the effect).	tmpzr1t_l9r_go_relaxed.owl	conditional learning|classical conditioning|conditional response|Pavlovian conditioning				Wikipedia:Learning#Associative_learning									biological_process											owl:Class	
GO:0009408	biolink:NamedThing	response to heat	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.	tmpzr1t_l9r_go_relaxed.owl	response to heat shock											GO:0006951		biological_process											owl:Class	
GO:0046307	biolink:NamedThing	Z-phenylacetaldoxime biosynthetic process	The chemical reactions and pathways resulting in the formation of Z-phenylacetaldoxime, a member of the glucosinolate group of compounds.	tmpzr1t_l9r_go_relaxed.owl	Z-phenylacetaldoxime formation|Z-phenylacetaldoxime anabolism|Z-phenylacetaldoxime biosynthesis|Z-phenylacetaldoxime synthesis													biological_process											owl:Class	
GO:0001907	biolink:NamedThing	killing by symbiont of host cells	Any process mediated by an organism that results in the death of cells in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	pathogenesis													biological_process											owl:Class	
GO:0003032	biolink:NamedThing	detection of oxygen	The series of events in which an oxygen stimulus is received by a cell and converted into a molecular signal.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0045633	biolink:NamedThing	positive regulation of mechanoreceptor differentiation	Any process that activates or increases the frequency, rate or extent of mechanoreceptor differentiation.	tmpzr1t_l9r_go_relaxed.owl	upregulation of mechanoreceptor differentiation|activation of mechanoreceptor differentiation|stimulation of mechanoreceptor differentiation|up-regulation of mechanoreceptor differentiation|up regulation of mechanoreceptor differentiation													biological_process											owl:Class	
GO:0032814	biolink:NamedThing	regulation of natural killer cell activation	Any process that modulates the frequency, rate or extent of natural killer cell activation.	tmpzr1t_l9r_go_relaxed.owl	regulation of NK cell activation													biological_process											owl:Class	
GO:0019671	biolink:NamedThing	glutamate catabolic process via mesaconate and citramalate	The anaerobic chemical reactions and pathways resulting in the breakdown of glutamate via the intermediates mesaconate and S-citramalate, yielding energy in the form of ATP.	tmpzr1t_l9r_go_relaxed.owl	glutamate fermentation via mesaconate and citramalate				MetaCyc:GLUDEG-II-PWY|MetaCyc:PWY-5087|MetaCyc:PWY-5088									biological_process											owl:Class	
GO:0010951	biolink:NamedThing	negative regulation of endopeptidase activity	Any process that decreases the frequency, rate or extent of endopeptidase activity, the endohydrolysis of peptide bonds within proteins.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-04-27T11:47:01Z					biological_process											owl:Class	
GO:0051779	biolink:NamedThing	gibberellin 12-aldehyde oxidase activity	Catalysis of the reaction: gibberellin 12-aldehyde + NADPH + H+ + O2 = gibberellin 12 + NADP+ + H2O. This is the third of three successive reactions resulting in the oxidation of ent-kaurenoate (ent-kaurenoic acid) to gibberellin 12 (GA12).	tmpzr1t_l9r_go_relaxed.owl	GA12-aldehyde oxidase activity				RHEA:22700|MetaCyc:RXN1F-161	Note that the enzyme ent-kaurenoate oxidase also catalyzes the reactions represented by the molecular function terms 'ent-kaurenoate oxidase activity ; GO:0051777' and 'ent-7-alpha-hydroxykaurenoate oxidase activity ; GO:0051778'.								molecular_function											owl:Class	
GO:0097221	biolink:NamedThing	M/G1 phase-specific MADS box-forkhead transcription factor complex	A protein complex that contains a MADS-box protein and two forkhead domain proteins, and binds to and regulates transcription from promoters of genes transcribed during the M/G1 transition of the cell cycle. In Schizosaccharomyces pombe, the complex contains the MADS-box protein Mbx1 and two forkhead proteins, Sep1 and Fkh2.	tmpzr1t_l9r_go_relaxed.owl	pombe cell cycle box binding factor complex|PCB binding factor complex|PBF complex|PBF transcription complex							pr	2012-01-18T08:18:27Z					cellular_component											owl:Class	
GO:0044879	biolink:NamedThing	mitotic morphogenesis checkpoint signaling	A signaling process that contributes to a mitotic cell cycle checkpoint which delays mitotic onset in response to perturbations that affect cell shape via the actin cytoskeleton, septin organization, small cell size, and/or the extent of membrane growth.	tmpzr1t_l9r_go_relaxed.owl	signaling pathway involved in septin checkpoint|septin checkpoint|signalling pathway involved in septin checkpoint|signaling pathway involved in morphogenesis checkpoint|signalling pathway involved in morphogenesis checkpoint|signal transduction involved in septin checkpoint|signalling cascade involved in septin checkpoint|signaling cascade involved in septin checkpoint|signaling cascade involved in morphogenesis checkpoint|morphogenesis checkpoint|signal transduction involved in morphogenesis checkpoint|signalling cascade involved in morphogenesis checkpoint	https://github.com/geneontology/go-ontology/issues/20935						jl	2015-01-13T16:03:07Z			GO:1903822		biological_process											owl:Class	
GO:0071217	biolink:NamedThing	cellular response to external biotic stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external biotic stimulus, an external stimulus caused by, or produced by living things.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-12-03T01:14:27Z					biological_process											owl:Class	
GO:0070879	biolink:NamedThing	fungal-type cell wall beta-glucan metabolic process	The chemical reactions and pathways involving beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds, found in the walls of fungal cells.	tmpzr1t_l9r_go_relaxed.owl	fungal-type cell wall beta-glucan metabolism							mah	2009-08-21T02:46:09Z					biological_process											owl:Class	
GO:0044640	biolink:NamedThing	envenomation resulting in negative regulation of complement activation, lectin pathway in other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant negative regulation of complement activation via the lectin pathway in the bitten/stung organism.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-07-05T04:56:30Z					biological_process											owl:Class	
GO:0044639	biolink:NamedThing	envenomation resulting in modulation of complement activation, lectin pathway in other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant modulation of complement activation via the lectin pathway in the bitten/stung organism.	tmpzr1t_l9r_go_relaxed.owl	envenomation resulting in regulation of complement activation, lectin pathway in other organism							jl	2012-07-05T04:53:36Z					biological_process											owl:Class	
GO:0010661	biolink:NamedThing	positive regulation of muscle cell apoptotic process	Any process that increases the rate or frequency of muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a muscle cell and result in its death.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of muscle cell apoptosis													biological_process											owl:Class	
GO:0019545	biolink:NamedThing	arginine catabolic process to succinate	The chemical reactions and pathways resulting in the breakdown of arginine into other compounds, including succinate.	tmpzr1t_l9r_go_relaxed.owl	arginine breakdown to succinate|arginine degradation to succinate				MetaCyc:ARGDEG-V-PWY|MetaCyc:ARGDEG-III-PWY|MetaCyc:ARGDEG-IV-PWY|MetaCyc:AST-PWY									biological_process											owl:Class	
GO:0006527	biolink:NamedThing	arginine catabolic process	The chemical reactions and pathways resulting in the breakdown of arginine, 2-amino-5-(carbamimidamido)pentanoic acid.	tmpzr1t_l9r_go_relaxed.owl	arginine breakdown|arginine degradation|arginine catabolism													biological_process											owl:Class	
GO:0061089	biolink:NamedThing	negative regulation of sequestering of zinc ion	Any process that decreases the rate, frequency, or extent of sequestering of zinc ion. Sequestering of zinc ion is the process of binding or confining zinc ions such that they are separated from other components of a biological system.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-04-26T01:38:53Z					biological_process											owl:Class	
GO:0006056	biolink:NamedThing	mannoprotein metabolic process	The chemical reactions and pathways involving a mannoprotein, a protein that contains covalently bound mannose residues.	tmpzr1t_l9r_go_relaxed.owl	mannoprotein metabolism													biological_process											owl:Class	
GO:0034408	biolink:NamedThing	ascospore wall beta-glucan metabolic process	The chemical reactions and pathways involving beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds, found in the walls of ascospores.	tmpzr1t_l9r_go_relaxed.owl	ascospore wall beta-glucan metabolism													biological_process											owl:Class	
GO:0010914	biolink:NamedThing	positive regulation of sterigmatocystin biosynthetic process	Any process that increases the rate, frequency, or extent of sterigmatocystin biosynthesis. Sterigmatocystin biosynthetic processes are the chemical reactions and pathways resulting in the formation of sterigmatocystin, a carcinogenic mycotoxin produced in high yields by strains of the common molds.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1905134	biolink:NamedThing	positive regulation of meiotic chromosome separation	Any process that activates or increases the frequency, rate or extent of meiotic chromosome separation.	tmpzr1t_l9r_go_relaxed.owl	upregulation of meiotic chromosome resolution|upregulation of chromosome separation during meiosis|up-regulation of chromosome separation during meiosis|activation of meiotic chromosome separation|up regulation of chromosome separation during meiosis|up-regulation of meiotic chromosome resolution|activation of meiotic chromosome resolution|activation of chromosome separation during meiosis|up-regulation of meiotic chromosome separation|upregulation of meiotic chromosome separation|up regulation of meiotic chromosome resolution|positive regulation of meiotic chromosome resolution|up regulation of meiotic chromosome separation|positive regulation of chromosome separation during meiosis							dph	2016-04-12T17:46:45Z					biological_process											owl:Class	
GO:1905132	biolink:NamedThing	regulation of meiotic chromosome separation	Any process that modulates the frequency, rate or extent of meiotic chromosome separation.	tmpzr1t_l9r_go_relaxed.owl	regulation of chromosome separation during meiosis|regulation of meiotic chromosome resolution							dph	2016-04-12T17:46:29Z					biological_process											owl:Class	
GO:0071599	biolink:NamedThing	otic vesicle development	The process whose specific outcome is the progression of the otic vesicle over time, from its formation to the mature structure. The otic vesicle is a transient embryonic structure formed during development of the vertebrate inner ear.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-02-04T04:07:17Z					biological_process											owl:Class	
GO:0099191	biolink:NamedThing	trans-synaptic signaling by BDNF	Cell-cell signaling between presynapse and postsynapse mediated by brain-derived neurotrophic factor (BDNF) crossing the synaptic cleft.	tmpzr1t_l9r_go_relaxed.owl	trans-synaptic signaling by brain-derived neurotrophic factor							dos	2017-12-20T15:48:33Z					biological_process											owl:Class	
GO:0097565	biolink:NamedThing	right middle basal body pair	Set of two basal bodies found in Giardia species (trophozoite stage). It comprises the caudal and posteriolateral basal bodies located to the left of the right nucleus of the trophozoite when viewed dorsally.	tmpzr1t_l9r_go_relaxed.owl						Due to the asymmetric nature of the Giardia trophozoite, this term is defined spatially as the trophozoite is viewed from the dorsal side, with the two nuclei dorsal to the ventral disc, and the ventral disc toward the anterior.		pr	2014-02-05T16:14:05Z					cellular_component											owl:Class	
GO:0090328	biolink:NamedThing	regulation of olfactory learning	Any process that modulates the rate, frequency, or extent of olfactory learning. Olfactory learning is any process in an organism in which a relatively long-lasting adaptive behavioral change occurs in response to (repeated) exposure to an olfactory cue.	tmpzr1t_l9r_go_relaxed.owl								tb	2010-05-14T10:37:22Z					biological_process											owl:Class	
GO:0018180	biolink:NamedThing	protein desulfurization	The removal of a sulfur group from a protein amino acid.	tmpzr1t_l9r_go_relaxed.owl	protein amino acid desulfurization|protein amino acid desulphurization|protein amino acid desulfurisation|protein amino acid desulphurisation													biological_process											owl:Class	
GO:0034178	biolink:NamedThing	toll-like receptor 13 signaling pathway	Any series of molecular signals generated as a consequence of binding to toll-like receptor 13.	tmpzr1t_l9r_go_relaxed.owl	toll-like receptor 13 signalling pathway|TLR13 signaling pathway													biological_process											owl:Class	
GO:0008399	biolink:NamedThing	naphthalene hydroxylase activity	Catalysis of the conversion of naphthalene to naphthalene 1,2-oxide.	tmpzr1t_l9r_go_relaxed.owl	cytochrome P450 CYP2F2													molecular_function											owl:Class	
GO:0006050	biolink:NamedThing	mannosamine metabolic process	The chemical reactions and pathways involving mannosomine, 2-amino-2-deoxymannose; the D-isomer is a constituent of neuraminic acids as well as mucolipids and mucoproteins.	tmpzr1t_l9r_go_relaxed.owl	mannosamine metabolism													biological_process											owl:Class	
GO:0099604	biolink:NamedThing	ligand-gated calcium channel activity	Enables the transmembrane transfer of a calcium ions by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1903586	biolink:NamedThing	positive regulation of histone deubiquitination	Any process that activates or increases the frequency, rate or extent of histone deubiquitination.	tmpzr1t_l9r_go_relaxed.owl	upregulation of histone deubiquitination|activation of histone deubiquitinylation|upregulation of histone deubiquitinylation|positive regulation of histone deubiquitylation|upregulation of histone deubiquitylation|activation of histone deubiquitination|up-regulation of histone deubiquitylation|activation of histone deubiquitylation|up-regulation of histone deubiquitinylation|up regulation of histone deubiquitinylation|up regulation of histone deubiquitylation|up regulation of histone deubiquitination|positive regulation of histone deubiquitinylation|up-regulation of histone deubiquitination							lb	2014-11-03T13:47:44Z					biological_process											owl:Class	
GO:0004801	biolink:NamedThing	transaldolase activity	Catalysis of the reaction: sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = D-erythrose 4-phosphate + D-fructose 6-phosphate.	tmpzr1t_l9r_go_relaxed.owl	glycerone transferase activity|dihydroxyacetone transferase activity|dihydroxyacetonetransferase activity|sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity	https://github.com/geneontology/go-ontology/issues/20486			Reactome:R-HSA-5659998|RHEA:17053|EC:2.2.1.2|Reactome:R-HSA-163764|MetaCyc:TRANSALDOL-RXN|Reactome:R-HSA-5659989|Reactome:R-HSA-71334									molecular_function											owl:Class	
GO:0042756	biolink:NamedThing	drinking behavior	The specific behavior of an organism relating to the intake of liquids, especially water.	tmpzr1t_l9r_go_relaxed.owl	drinking behaviour													biological_process											owl:Class	
GO:0016327	biolink:NamedThing	apicolateral plasma membrane	The apical end of the lateral plasma membrane of epithelial cells.	tmpzr1t_l9r_go_relaxed.owl	apical lateral plasma membrane													cellular_component											owl:Class	
GO:0070672	biolink:NamedThing	response to interleukin-15	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-15 stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to IL-15							mah	2009-05-29T10:03:09Z					biological_process											owl:Class	
GO:0099524	biolink:NamedThing	postsynaptic cytosol	The region of the cytosol consisting of all cytosol that is part of the postsynapse.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0099522	biolink:NamedThing	cytosolic region	Any (proper) part of the cytosol of a single cell of sufficient size to still be considered cytosol.	tmpzr1t_l9r_go_relaxed.owl	region of cytosol													cellular_component											owl:Class	
GO:1904891	biolink:NamedThing	positive regulation of excitatory synapse assembly	Any process that activates or increases the frequency, rate or extent of excitatory synapse assembly.	tmpzr1t_l9r_go_relaxed.owl	upregulation of excitatory synapse formation|up regulation of excitatory synapse assembly|activation of excitatory synapse formation|up-regulation of excitatory synapse formation|positive regulation of excitatory synapse formation|up regulation of excitatory synapse formation|up-regulation of excitatory synapse assembly|activation of excitatory synapse assembly|upregulation of excitatory synapse assembly							bf	2016-01-07T14:36:07Z					biological_process											owl:Class	
GO:0075342	biolink:NamedThing	disruption by symbiont of host cell PML body	The breakdown, by the symbiont, of a PML body within a host cell. A PML body is a nuclear body that reacts against SP100 auto-antibodies (PML = promyelocytic leukemia). The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	disassembly by symbiont of host cell PML body|catabolism by symbiont of host cell PML body|disassembly by symbiont of host cell PML nuclear body|disassembly by symbiont of host cell PML NB|degradation by symbiont of host cell PML body|disassembly by symbiont of host cell PML body during symbiotic interaction													biological_process											owl:Class	
GO:0052008	biolink:NamedThing	disruption by symbiont of host cellular component	The chemical reactions and pathways performed by an organism resulting in the breakdown of cellular components of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	catabolism of host cellular component by organism|catabolism of host structural constituent by organism|disassembly by symbiont of host cellular component|degradation of host cellular component by organism|disassembly by organism of host cellular component													biological_process											owl:Class	
GO:0009810	biolink:NamedThing	stilbene metabolic process	The chemical reactions and pathways involving stilbenes, a class of polyketides formed from a molecule of cinnamic acid and three molecules of malonyl-CoA.	tmpzr1t_l9r_go_relaxed.owl	stilbene metabolism													biological_process											owl:Class	
GO:0061004	biolink:NamedThing	pattern specification involved in kidney development	Any developmental process that results in the creation of defined areas or spaces within the kidney to which cells respond and eventually are instructed to differentiate.	tmpzr1t_l9r_go_relaxed.owl	kidney pattern formation|pattern formation involved in kidney development|kidney pattern specification							dph	2010-01-21T09:05:54Z					biological_process											owl:Class	
GO:0034137	biolink:NamedThing	positive regulation of toll-like receptor 2 signaling pathway	Any process that activates or increases the frequency, rate, or extent of toll-like receptor 2 signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of toll-like receptor 2 signalling pathway|positive regulation of TLR2 signaling pathway													biological_process											owl:Class	
GO:0033388	biolink:NamedThing	putrescine biosynthetic process from arginine	The chemical reactions and pathways resulting in the formation of putrescine, 1,4-diaminobutane, from other compounds, including arginine.	tmpzr1t_l9r_go_relaxed.owl	putrescine synthesis from arginine|putrescine biosynthesis from arginine|putrescine anabolism from arginine|putrescine formation from arginine													biological_process											owl:Class	
GO:0004851	biolink:NamedThing	uroporphyrin-III C-methyltransferase activity	Catalysis of the reaction: 2 S-adenosyl-L-methionine + uroporphyrin III = 2 S-adenosyl-L-homocysteine + precorrin-2.	tmpzr1t_l9r_go_relaxed.owl	CysG|S-adenosyl-L-methionine:uroporphyrinogen-III C-methyltransferase activity|S-adenosyl-L-methionine-dependent uroporphyrinogen III methylase activity|SUMT activity|SirA|uroporphyrinogen-III methyltransferase activity|S-adenosyl-L-methionine:uroporphyrin-III C-methyltransferase activity|uroporphyrinogen III methylase activity|uroporphyrinogen-III methylase activity|uroporphyrinogen-III C-methyltransferase activity|adenosylmethionine-uroporphyrinogen III methyltransferase activity|uroporphyrinogen methyltransferase activity|CobA|urogen III methylase activity				MetaCyc:UROPORIIIMETHYLTRANSA-RXN|EC:2.1.1.107|RHEA:32459									molecular_function											owl:Class	
GO:0010850	biolink:NamedThing	regulation of blood pressure by chemoreceptor signaling pathway	A series of reactions within the cell that occur as a result of a single trigger reaction or compound interacting with a chemoreceptor resulting in a modulation of the force with which blood travels through the circulatory system. Chemoreceptors respond to oxygen, carbon dioxide and hydrogen ions.	tmpzr1t_l9r_go_relaxed.owl	regulation of blood pressure by chemoreceptor signalling pathway													biological_process											owl:Class	
GO:0034104	biolink:NamedThing	negative regulation of tissue remodeling	Any process that stops, prevents, or reduces the frequency, rate, or extent of tissue remodeling.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0060602	biolink:NamedThing	branch elongation of an epithelium	The growth process in which a branch increases in length from its base to its tip.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-05-14T02:45:44Z					biological_process											owl:Class	
GO:0090686	biolink:NamedThing	glycine betaine-activated nonselective monovalent cation channel activity	Enables the transmembrane transfer of a monovalent cation by a channel that opens when glycine betaine has been bound by the channel complex or one of its constituent parts.	tmpzr1t_l9r_go_relaxed.owl								tb	2016-07-20T16:29:01Z					molecular_function											owl:Class	
GO:0050154	biolink:NamedThing	opheline kinase activity	Catalysis of the reaction: ATP + guanidinoethyl methyl phosphate = N'-phosphoguanidinoethyl methylphosphate + ADP + 2 H(+).	tmpzr1t_l9r_go_relaxed.owl	ATP:guanidinoethyl-methyl-phosphate phosphotransferase activity				MetaCyc:OPHELINE-KINASE-RXN|KEGG_REACTION:R04388|RHEA:17553|EC:2.7.3.7									molecular_function											owl:Class	
GO:1904530	biolink:NamedThing	negative regulation of actin filament binding	Any process that stops, prevents or reduces the frequency, rate or extent of actin filament binding.	tmpzr1t_l9r_go_relaxed.owl	inhibition of F-actin binding|inhibition of actin filament binding|negative regulation of actin cross-linking activity|down regulation of actin filament binding|down-regulation of actin cross-linking activity|inhibition of actin cross-linking activity|downregulation of F-actin binding|down-regulation of actin filament binding|down regulation of F-actin binding|negative regulation of F-actin binding|downregulation of actin cross-linking activity|down-regulation of F-actin binding|down regulation of actin cross-linking activity|downregulation of actin filament binding							als	2015-07-30T10:41:55Z					biological_process											owl:Class	
GO:1990682	biolink:NamedThing	CSF1-CSF1R complex	A protein complex consisting of a macrophage colony-stimulating factor (CSF1, also called M-CSF) dimer bound to a dimerized receptor (CSF1R, also called FMS). Receptor dimerization requires the presence of the ligand.	tmpzr1t_l9r_go_relaxed.owl	CSF1:C-FMS complex|M-CSF:FMS complex|M-CSF:C-FMS complex|macrophage colony-stimulating factor:receptor complex|M-CSF:CSF1R complex							bf	2015-03-10T12:23:03Z					cellular_component											owl:Class	
GO:0140605	biolink:NamedThing	proton motive force-driven motor activity	A motor activity driven by an electrochemical proton gradient (proton-motive force). PMF-driven motors are used by bacterial flagella.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/19590						pg	2021-02-17T08:04:50Z					molecular_function											owl:Class	
GO:0003774	biolink:NamedThing	cytoskeletal motor activity	Generation of force resulting in movement, for example along a microfilament or microtubule, or in torque resulting in membrane scission or rotation of a flagellum. The energy required is obtained either from the hydrolysis of a nucleoside triphosphate or by an electrochemical proton gradient (proton-motive force).	tmpzr1t_l9r_go_relaxed.owl	motor activity	https://github.com/geneontology/go-ontology/issues/21756|https://github.com/geneontology/go-ontology/issues/19590			Reactome:R-HSA-1861595									molecular_function											owl:Class	
GO:1902964	biolink:NamedThing	positive regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process	Any process that activates or increases the frequency, rate or extent of metalloendopeptidase activity involved in amyloid precursor protein catabolic process.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of metalloendoproteinase activity involved in amyloid precursor protein catabolic process|activation of metalloendoprotease activity involved in amyloid precursor protein catabolic process|activation of metalloendoproteinase activity involved in amyloid precursor protein breakdown|activation of metalloendoproteinase activity involved in amyloid precursor protein catabolism|up regulation of metalloendopeptidase activity involved in APP catabolism|up regulation of metalloendoprotease activity involved in APP catabolism|up-regulation of metalloendoproteinase activity involved in amyloid precursor protein catabolism|up regulation of metalloendoprotease activity involved in amyloid precursor protein breakdown|positive regulation of metalloendopeptidase activity involved in amyloid precursor protein degradation|up-regulation of metalloendoprotease activity involved in amyloid precursor protein catabolism|positive regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolism|activation of metalloendoprotease activity involved in amyloid precursor protein catabolism|up regulation of metalloendoproteinase activity involved in APP catabolism|upregulation of metalloendoproteinase activity involved in amyloid precursor protein degradation|up-regulation of metalloendoprotease activity involved in amyloid precursor protein breakdown|upregulation of metalloendoprotease activity involved in APP catabolism|up-regulation of metalloendoprotease activity involved in amyloid precursor protein catabolic process|up regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process|positive regulation of metalloendoprotease activity involved in amyloid precursor protein breakdown|positive regulation of metalloendoproteinase activity involved in amyloid precursor protein degradation|positive regulation of metalloendoproteinase activity involved in APP catabolic process|activation of metalloendopeptidase activity involved in APP catabolic process|upregulation of metalloendoproteinase activity involved in APP catabolism|up regulation of metalloendoprotease activity involved in amyloid precursor protein catabolism|activation of metalloendoprotease activity involved in amyloid precursor protein breakdown|upregulation of metalloendopeptidase activity involved in amyloid precursor protein breakdown|activation of metalloendopeptidase activity involved in amyloid precursor protein degradation|up regulation of metalloendoprotease activity involved in amyloid precursor protein degradation|activation of metalloendopeptidase activity involved in amyloid precursor protein breakdown|up regulation of metalloendoprotease activity involved in amyloid precursor protein catabolic process|up-regulation of metalloendoproteinase activity involved in amyloid precursor protein breakdown|activation of metalloendoprotease activity involved in APP catabolism|positive regulation of metalloendopeptidase activity involved in APP catabolic process|upregulation of metalloendoprotease activity involved in amyloid precursor protein catabolic process|positive regulation of metalloendoprotease activity involved in amyloid precursor protein degradation|up-regulation of metalloendopeptidase activity involved in APP catabolism|positive regulation of metalloendoprotease activity involved in amyloid precursor protein catabolism|upregulation of metalloendoprotease activity involved in APP catabolic process|positive regulation of metalloendoprotease activity involved in APP catabolic process|up-regulation of metalloendoprotease activity involved in APP catabolism|up regulation of metalloendoproteinase activity involved in amyloid precursor protein degradation|activation of metalloendopeptidase activity involved in APP catabolism|positive regulation of metalloendopeptidase activity involved in amyloid precursor protein breakdown|activation of metalloendopeptidase activity involved in amyloid precursor protein catabolism|up regulation of metalloendopeptidase activity involved in APP catabolic process|upregulation of metalloendoproteinase activity involved in APP catabolic process|up-regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process|up regulation of metalloendoproteinase activity involved in amyloid precursor protein catabolic process|up-regulation of metalloendoprotease activity involved in APP catabolic process|up regulation of metalloendoproteinase activity involved in APP catabolic process|up regulation of metalloendopeptidase activity involved in amyloid precursor protein breakdown|up-regulation of metalloendoprotease activity involved in amyloid precursor protein degradation|up-regulation of metalloendoproteinase activity involved in APP catabolism|upregulation of metalloendopeptidase activity involved in amyloid precursor protein degradation|positive regulation of metalloendopeptidase activity involved in APP catabolism|up-regulation of metalloendoproteinase activity involved in APP catabolic process|positive regulation of metalloendoproteinase activity involved in amyloid precursor protein breakdown|up regulation of metalloendoproteinase activity involved in amyloid precursor protein catabolism|up regulation of metalloendoproteinase activity involved in amyloid precursor protein breakdown|up-regulation of metalloendoproteinase activity involved in amyloid precursor protein catabolic process|upregulation of metalloendoprotease activity involved in amyloid precursor protein breakdown|up-regulation of metalloendopeptidase activity involved in APP catabolic process|upregulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process|up-regulation of metalloendopeptidase activity involved in amyloid precursor protein degradation|activation of metalloendoproteinase activity involved in amyloid precursor protein degradation|activation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process|positive regulation of metalloendoproteinase activity involved in APP catabolism|upregulation of metalloendopeptidase activity involved in APP catabolic process|upregulation of metalloendopeptidase activity involved in APP catabolism|up-regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolism|upregulation of metalloendoprotease activity involved in amyloid precursor protein degradation|upregulation of metalloendopeptidase activity involved in amyloid precursor protein catabolism|upregulation of metalloendoproteinase activity involved in amyloid precursor protein breakdown|up regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolism|activation of metalloendoprotease activity involved in amyloid precursor protein degradation|activation of metalloendoproteinase activity involved in APP catabolic process|activation of metalloendoproteinase activity involved in amyloid precursor protein catabolic process|activation of metalloendoproteinase activity involved in APP catabolism|up regulation of metalloendoprotease activity involved in APP catabolic process|upregulation of metalloendoproteinase activity involved in amyloid precursor protein catabolic process|positive regulation of metalloendoproteinase activity involved in amyloid precursor protein catabolism|up-regulation of metalloendopeptidase activity involved in amyloid precursor protein breakdown|upregulation of metalloendoproteinase activity involved in amyloid precursor protein catabolism|activation of metalloendoprotease activity involved in APP catabolic process|up-regulation of metalloendoproteinase activity involved in amyloid precursor protein degradation|up regulation of metalloendopeptidase activity involved in amyloid precursor protein degradation|upregulation of metalloendoprotease activity involved in amyloid precursor protein catabolism|positive regulation of metalloendoprotease activity involved in amyloid precursor protein catabolic process|positive regulation of metalloendoprotease activity involved in APP catabolism							sjp	2014-05-06T09:12:11Z					biological_process											owl:Class	
GO:0043145	biolink:NamedThing	sno(s)RNA 3'-end cleavage	The endonucleolytic cleavage of snoRNA 3' ends, which is required for mature snoRNAs to be functional.	tmpzr1t_l9r_go_relaxed.owl	snoRNA 3'-end cleavage|sRNA 3'-end cleavage|sno(s)RNA 3' end cleavage	https://github.com/geneontology/go-ontology/issues/20416												biological_process											owl:Class	
GO:0047744	biolink:NamedThing	chloridazon-catechol dioxygenase activity	Catalysis of the reaction: 5-amino-4-chloro-2-(2,3-dihydroxyphenyl)pyridazin-3(2H)-one + O(2) = 5-amino-4-chloro-2-(2-hydroxymuconoyl)pyridazin-3(2H)-one + 2 H(+).	tmpzr1t_l9r_go_relaxed.owl	5-amino-4-chloro-2-(2,3-dihydroxyphenyl)-3(2H)-pyridazinone 1,2-oxidoreductase (decyclizing)				MetaCyc:CHLORIDAZON-CATECHOL-DIOXYGENASE-RXN|KEGG_REACTION:R04602|EC:1.13.11.36|RHEA:20449									molecular_function											owl:Class	
GO:0042420	biolink:NamedThing	dopamine catabolic process	The chemical reactions and pathways resulting in the breakdown of dopamine, a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline.	tmpzr1t_l9r_go_relaxed.owl	dopamine breakdown|dopamine catabolism|dopamine degradation													biological_process											owl:Class	
GO:0034242	biolink:NamedThing	negative regulation of syncytium formation by plasma membrane fusion	Any process that decreases the frequency, rate or extent of the formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0034964	biolink:NamedThing	box H/ACA RNA processing	Any process involved in the conversion of a primary box H/ACA type small  RNA transcript into a mature box H/ACA RNA.	tmpzr1t_l9r_go_relaxed.owl	box H/ACA sRNA processing|box H/ACA snoRNA processing	https://github.com/geneontology/go-ontology/issues/20416												biological_process											owl:Class	
GO:0034319	biolink:NamedThing	alcohol O-butanoyltransferase activity	Catalysis of the reaction: butanoyl-CoA + an alcohol = CoA + a butyl ester.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1901405	biolink:NamedThing	negative regulation of tetrapyrrole catabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of tetrapyrrole catabolic process.	tmpzr1t_l9r_go_relaxed.owl	down regulation of tetrapyrrole catabolic process|downregulation of tetrapyrrole catabolic process|down regulation of tetrapyrrole degradation|negative regulation of tetrapyrrole catabolism|inhibition of tetrapyrrole catabolism|down-regulation of tetrapyrrole degradation|down-regulation of tetrapyrrole catabolism|down regulation of tetrapyrrole breakdown|downregulation of tetrapyrrole breakdown|down-regulation of tetrapyrrole catabolic process|downregulation of tetrapyrrole catabolism|inhibition of tetrapyrrole degradation|down regulation of tetrapyrrole catabolism|negative regulation of tetrapyrrole degradation|inhibition of tetrapyrrole breakdown|down-regulation of tetrapyrrole breakdown|negative regulation of tetrapyrrole breakdown|downregulation of tetrapyrrole degradation|inhibition of tetrapyrrole catabolic process							tt	2012-10-01T14:39:22Z					biological_process											owl:Class	
GO:1904695	biolink:NamedThing	positive regulation of vascular associated smooth muscle contraction	Any process that activates or increases the frequency, rate or extent of vascular smooth muscle contraction.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of vascular smooth muscle contraction|activation of vascular smooth muscle contraction|up-regulation of vascular smooth muscle contraction|upregulation of vascular smooth muscle contraction|up regulation of vascular smooth muscle contraction							rph	2015-09-29T13:39:14Z					biological_process											owl:Class	
GO:0015796	biolink:NamedThing	galactitol transport	The directed movement of galactitol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Galactitol is the hexitol derived by the reduction of the aldehyde group of either D- or L-galactose.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0001937	biolink:NamedThing	negative regulation of endothelial cell proliferation	Any process that stops, prevents, or reduces the rate or extent of endothelial cell proliferation.	tmpzr1t_l9r_go_relaxed.owl	downregulation of endothelial cell proliferation|down-regulation of endothelial cell proliferation|down regulation of endothelial cell proliferation|inhibition of endothelial cell proliferation													biological_process											owl:Class	
GO:0031286	biolink:NamedThing	negative regulation of sorocarp stalk cell differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of sorocarp stalk cell differentiation. An example of this process is found in Dictyostelium discoideum.	tmpzr1t_l9r_go_relaxed.owl	downregulation of stalk cell differentiation|down-regulation of stalk cell differentiation|negative regulation of stalk cell differentiation|inhibition of stalk cell differentiation|down regulation of stalk cell differentiation													biological_process											owl:Class	
GO:0046203	biolink:NamedThing	spermidine catabolic process	The chemical reactions and pathways resulting in the breakdown of spermidine, N-(3-aminopropyl)-1,4-diaminobutane.	tmpzr1t_l9r_go_relaxed.owl	spermidine breakdown|spermidine catabolism|spermidine degradation													biological_process											owl:Class	
GO:0019488	biolink:NamedThing	ribitol catabolic process to xylulose 5-phosphate	The chemical reactions and pathways resulting in the breakdown of ribitol to form xylulose 5-phosphate. Ribitol is initially converted to D-ribulose, which is phosphorylated to form ribulose 5-phosphate, which is then converted into xylulose 5-phosphate.	tmpzr1t_l9r_go_relaxed.owl	ribitol degradation to xylulose 5-phosphate|ribitol breakdown to xylulose 5-phosphate|ribitol utilization				MetaCyc:RIBITOLUTIL-PWY									biological_process											owl:Class	
GO:0046363	biolink:NamedThing	ribitol catabolic process	The chemical reactions and pathways resulting in the breakdown of ribitol, a pentitol derived formally by reduction of the -CHO group of either D- or L-ribose.	tmpzr1t_l9r_go_relaxed.owl	ribitol degradation|ribitol breakdown|ribitol catabolism													biological_process											owl:Class	
GO:0001729	biolink:NamedThing	ceramide kinase activity	Catalysis of the reaction: ATP + ceramide = ADP + ceramide-1-phosphate.	tmpzr1t_l9r_go_relaxed.owl	acylsphingosine kinase activity|ATP:ceramide 1-phosphotransferase activity				MetaCyc:CERAMIDE-KINASE-RXN|EC:2.7.1.138|RHEA:17929|Reactome:R-HSA-1638845									molecular_function											owl:Class	
GO:0001727	biolink:NamedThing	lipid kinase activity	Catalysis of the phosphorylation of a simple or complex lipid.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0004071	biolink:NamedThing	aspartate-ammonia ligase activity	Catalysis of the reaction: ATP + L-aspartate + NH3 = AMP + diphosphate + L-asparagine.	tmpzr1t_l9r_go_relaxed.owl	L-aspartate:ammonia ligase (AMP-forming)|asparagine synthetase activity|L-asparagine synthetase activity				EC:6.3.1.1|RHEA:11372|MetaCyc:ASNSYNA-RXN									molecular_function											owl:Class	
GO:0016211	biolink:NamedThing	ammonia ligase activity	Catalysis of the ligation of ammonia (NH3) to another substance via a carbon-nitrogen bond with concomitant breakage of a diphosphate linkage, usually in a nucleoside triphosphate.	tmpzr1t_l9r_go_relaxed.owl					EC:6.3.1.-									molecular_function											owl:Class	
GO:0035276	biolink:NamedThing	ethanol binding	Binding to ethanol, CH(3)-CH(2)-OH.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0010410	biolink:NamedThing	hemicellulose metabolic process	The chemical reactions and pathways involving hemicelluloses, plant cell wall polysaccharides that have a backbone of 1,4-linked beta-D-pyranosyl residues in which O4 is in the equatorial orientation. Many different hemicelluloses usually occur intermixed with each molecular type representing different degrees of polymerization and contain many different sugar monomers, which can include glucose, xylose, mannose, galactose, and arabinose. Hemicelluloses also contain most of the D-pentose sugars and occasionally small amounts of L-sugars as well. Xylose is always the sugar monomer present in the largest amount, but mannuronic acid and galacturonic acid also tend to be present.	tmpzr1t_l9r_go_relaxed.owl	hemicellulose metabolism													biological_process											owl:Class	
GO:0018984	biolink:NamedThing	naphthalenesulfonate metabolic process	The chemical reactions and pathways involving naphthalenesulfonate, sulfonated derivatives of naphthalene.	tmpzr1t_l9r_go_relaxed.owl	naphthalenesulphonate metabolism|naphthalenesulfonate metabolism|naphthalenesulphonate metabolic process				UM-BBD_pathwayID:nphs							GO:0018932		biological_process											owl:Class	
GO:0070637	biolink:NamedThing	pyridine nucleoside metabolic process	The chemical reactions and pathways involving any pyridine nucleoside, a nucleoside in which a pyridine base covalently bonded to a sugar, usually ribose.	tmpzr1t_l9r_go_relaxed.owl	pyridine nucleoside metabolism							mah	2009-05-07T02:24:21Z					biological_process											owl:Class	
GO:1900368	biolink:NamedThing	regulation of RNA interference	Any process that modulates the frequency, rate or extent of RNA interference.	tmpzr1t_l9r_go_relaxed.owl	regulation of posttranscriptional gene silencing by siRNA|regulation of RNAi							kmv	2012-04-13T08:28:39Z					biological_process											owl:Class	
GO:0032231	biolink:NamedThing	regulation of actin filament bundle assembly	Any process that modulates the frequency, rate or extent of the assembly of actin filament bundles.	tmpzr1t_l9r_go_relaxed.owl	regulation of actin filament bundle formation|regulation of actin cable assembly													biological_process											owl:Class	
GO:1904227	biolink:NamedThing	negative regulation of glycogen synthase activity, transferring glucose-1-phosphate	Any process that stops, prevents or reduces the frequency, rate or extent of glycogen synthase activity, transferring glucose-1-phosphate.	tmpzr1t_l9r_go_relaxed.owl	down regulation of glycogen synthase activity, transferring glucose-1-phosphate|inhibition of glycogen synthase activity, transferring glucose-1-phosphate|downregulation of glycogen synthase activity, transferring glucose-1-phosphate|down-regulation of glycogen synthase activity, transferring glucose-1-phosphate							rl	2015-05-15T09:23:14Z					biological_process											owl:Class	
GO:0019697	biolink:NamedThing	L-xylitol catabolic process to xylulose 5-phosphate	The chemical reactions and pathways resulting in the breakdown of L-xylitol to form xylulose 5-phosphate. L-xylitol is converted into L-xylulose, which is then phosphorylated to L-xylulose-5-phosphate. This is converted to D-xylulose-5-phosphate via the intermediate L-ribulose-5-phosphate.	tmpzr1t_l9r_go_relaxed.owl	L-arabitol and xylitol degradation|L-xylitol breakdown to xylulose 5-phosphate|L-xylitol degradation to xylulose 5-phosphate|L-xylitol utilization				MetaCyc:LARABITOLUTIL-PWY									biological_process											owl:Class	
GO:0031287	biolink:NamedThing	positive regulation of sorocarp stalk cell differentiation	Any process that activates or increases the frequency, rate or extent of sorocarp stalk cell differentiation. An example of this process is found in Dictyostelium discoideum.	tmpzr1t_l9r_go_relaxed.owl	up regulation of stalk cell differentiation|up-regulation of stalk cell differentiation|stimulation of stalk cell differentiation|positive regulation of stalk cell differentiation|activation of stalk cell differentiation|upregulation of stalk cell differentiation													biological_process											owl:Class	
GO:0102147	biolink:NamedThing	3'-O-methyltricetin O methyl transferase activity	Catalysis of the reaction: S-adenosyl-L-methionine  + 3'-O-methyltricetin = H+ + S-adenosyl-L-homocysteine  + 3',5'-di-O-methyltricetin.	tmpzr1t_l9r_go_relaxed.owl					RHEA:27497|MetaCyc:RXN-11583									molecular_function											owl:Class	
GO:1900111	biolink:NamedThing	positive regulation of histone H3-K9 dimethylation	Any process that activates or increases the frequency, rate or extent of histone H3-K9 dimethylation.	tmpzr1t_l9r_go_relaxed.owl	activation of histone H3-K9 dimethylation|up-regulation of histone lysine H3 K9 dimethylation|upregulation of histone H3-K9 dimethylation|activation of histone lysine H3 K9 dimethylation|positive regulation of histone lysine H3 K9 dimethylation|up-regulation of histone H3-K9 dimethylation|upregulation of histone lysine H3 K9 dimethylation|positive regulation of histone H3 K9 dimethylation|up regulation of histone H3 K9 dimethylation|activation of histone H3 K9 dimethylation|upregulation of histone H3 K9 dimethylation|up regulation of histone H3-K9 dimethylation|up regulation of histone lysine H3 K9 dimethylation|up-regulation of histone H3 K9 dimethylation							bf	2012-02-21T09:06:26Z					biological_process											owl:Class	
GO:1905707	biolink:NamedThing	negative regulation of mitochondrial ATP synthesis coupled proton transport	Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrial ATP synthesis coupled proton transport.	tmpzr1t_l9r_go_relaxed.owl								vw	2016-11-17T14:07:40Z					biological_process											owl:Class	
GO:0090628	biolink:NamedThing	plant epidermal cell fate specification	The process in which a cell becomes capable of differentiating autonomously into a plant epidermal cell in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed.	tmpzr1t_l9r_go_relaxed.owl								tb	2015-02-06T17:32:21Z					biological_process											owl:Class	
GO:1900845	biolink:NamedThing	positive regulation of monodictyphenone biosynthetic process	Any process that activates or increases the frequency, rate or extent of monodictyphenone biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	upregulation of monodictyphenone biosynthetic process							di	2012-06-07T09:41:08Z					biological_process											owl:Class	
GO:1905183	biolink:NamedThing	negative regulation of protein serine/threonine phosphatase activity	Any process that stops, prevents or reduces the frequency, rate or extent of protein serine/threonine phosphatase activity.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of serine/threonine specific protein phosphatase activity|inhibition of protein serine/threonine phosphatase activity|downregulation of protein serine/threonine phosphatase activity|down regulation of serine/threonine specific protein phosphatase activity|down regulation of protein serine/threonine phosphatase activity|downregulation of serine/threonine specific protein phosphatase activity|down-regulation of protein serine/threonine phosphatase activity|negative regulation of serine/threonine specific protein phosphatase activity|inhibition of serine/threonine specific protein phosphatase activity							mah	2016-05-10T15:28:04Z					biological_process											owl:Class	
GO:0051746	biolink:NamedThing	thalianol synthase activity	Catalysis of the cyclization of 3(S)-oxidosqualene to (3S,13S,14R)-malabarica-8,17,21-trien-3-ol (thalianol).	tmpzr1t_l9r_go_relaxed.owl					EC:5.4.99.31|RHEA:26160									molecular_function											owl:Class	
GO:0042578	biolink:NamedThing	phosphoric ester hydrolase activity	Catalysis of the reaction: RPO-R' + H2O = RPOOH + R'H. This reaction is the hydrolysis of any phosphoric ester bond, any ester formed from orthophosphoric acid, O=P(OH)3.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0002309	biolink:NamedThing	T cell proliferation involved in immune response	The expansion of a T cell population by cell division as part of an immune response.	tmpzr1t_l9r_go_relaxed.owl	T-lymphocyte proliferation during immune response|T lymphocyte proliferation during immune response|T-cell proliferation during immune response|T cell proliferation during immune response													biological_process											owl:Class	
GO:2000132	biolink:NamedThing	negative regulation of tyramine signaling pathway	Any process that stops, prevents, or reduces the frequency, rate or extent of tyramine signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of tyramine signalling pathway							mah	2010-09-29T09:32:00Z					biological_process											owl:Class	
GO:2000126	biolink:NamedThing	negative regulation of octopamine or tyramine signaling pathway	Any process that stops, prevents, or reduces the frequency, rate or extent of octopamine or tyramine signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of octopamine or tyramine signalling pathway|negative regulation of octopamine/tyramine signaling pathway							mah	2010-09-29T09:27:16Z					biological_process											owl:Class	
GO:0106092	biolink:NamedThing	glial cell projection elongation involved in axon ensheathment	The extension of a glial cell process or projection to wrap around an axon.	tmpzr1t_l9r_go_relaxed.owl								hjd	2018-01-26T19:43:00Z					biological_process											owl:Class	
GO:0044637	biolink:NamedThing	envenomation resulting in negative regulation of complement activation, classical pathway in other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the negative regulation of complement activation via the classical pathway of the bitten/stung organism.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-07-05T04:46:56Z					biological_process											owl:Class	
GO:0044636	biolink:NamedThing	envenomation resulting in modulation of complement activation, classical pathway in other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the regulation of complement activation via the classical pathway of the bitten/stung organism.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-07-05T04:40:57Z					biological_process											owl:Class	
GO:1990549	biolink:NamedThing	mitochondrial NAD transmembrane transport	The process in which NAD is transported across a mitochondrial membrane, into or out of the mitochondrion.	tmpzr1t_l9r_go_relaxed.owl								vw	2014-11-19T12:09:51Z					biological_process											owl:Class	
GO:0033426	biolink:NamedThing	CAC codon-amino acid adaptor activity	A triplet codon-amino acid adaptor activity that recognizes a CAC codon.	tmpzr1t_l9r_go_relaxed.owl	histidine tRNA					Note that in the standard genetic code, CAC codes for histidine.								molecular_function											owl:Class	
GO:0008838	biolink:NamedThing	diaminopropionate ammonia-lyase activity	Catalysis of the reaction: 2,3-diaminopropionate + H2O = pyruvate + 2 NH3.	tmpzr1t_l9r_go_relaxed.owl	alpha,beta-diaminopropionate ammonia-lyase activity|diaminopropionatase activity|2,3-diaminopropionate ammonia-lyase (adding H2O; pyruvate-forming)|2,3-diaminopropionate ammonia-lyase activity				MetaCyc:4.3.1.15-RXN|RHEA:22084|EC:4.3.1.15									molecular_function											owl:Class	
GO:0021945	biolink:NamedThing	positive regulation of cerebellar granule cell migration by calcium	The process that increases the extent of granule cell motility using intracellular calcium signaling mechanisms during radial migration.	tmpzr1t_l9r_go_relaxed.owl	calcium-mediated up regulation of granule cell migration|calcium-mediated up-regulation of granule cell migration|calcium-mediated stimulation of granule cell migration|calcium-mediated activation of granule cell migration|calcium-mediated upregulation of granule cell migration|calcium-mediated positive regulation of granule cell migration													biological_process											owl:Class	
GO:0102477	biolink:NamedThing	2,5,7-trihydroxyflavanone 6C-glucoside dehydratase activity	Catalysis of the reaction: 6C-glucosyl-2,5,7-trihydroxyflavanone <=> H+ + 6C-hexosyl chrysin + H2O.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-14088									molecular_function											owl:Class	
GO:0098723	biolink:NamedThing	skeletal muscle myofibril	A myofibril of a skeletal muscle fiber.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0030016	biolink:NamedThing	myofibril	The contractile element of skeletal and cardiac muscle; a long, highly organized bundle of actin, myosin, and other proteins that contracts by a sliding filament mechanism.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Myofibril									cellular_component											owl:Class	
GO:0004154	biolink:NamedThing	dihydropterin oxidase activity	Catalysis of the reaction: a 7,8-dihydropteridine + O2 = a pterin + hydrogen peroxide.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0004890	biolink:NamedThing	GABA-A receptor activity	Combining with the amino acid gamma-aminobutyric acid (GABA, 4-aminobutyrate) to initiate a change in cell activity. GABA-A receptors function as chloride channels.	tmpzr1t_l9r_go_relaxed.owl	ionotropic GABA receptor activity					Note that this term represents an activity and not a gene product. Consider also annotating to the molecular function term 'chloride channel activity ; GO:0005254' and 'inhibitory extracellular ligand-gated ion channel activity ; GO:0005237'.								molecular_function											owl:Class	
GO:0016917	biolink:NamedThing	GABA receptor activity	Combining with gamma-aminobutyric acid (GABA), and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. (GABA, 4-aminobutyrate) is an amino acid which acts as a neurotransmitter in some organisms.	tmpzr1t_l9r_go_relaxed.owl	GABA binding|4-aminobutyrate receptor activity|gamma-aminobutyric acid binding|gamma-aminobutyric acid receptor activity|4-aminobutanoate receptor activity|gamma-aminobutyrate binding					See also the molecular function term 'neurotransmitter receptor activity ; GO:0030594'.								molecular_function											owl:Class	
GO:0033525	biolink:NamedThing	sinapate ester biosynthetic process	The chemical reactions and pathways resulting in the formation of ester derivates of sinapate, (2E)-3-(4-hydroxy-3,5-dimethoxyphenyl)prop-2-enoate.	tmpzr1t_l9r_go_relaxed.owl	sinapate ester synthesis|sinapate ester formation|sinapate ester anabolism|sinapate ester biosynthesis				MetaCyc:PWY-3301									biological_process											owl:Class	
GO:0090074	biolink:NamedThing	negative regulation of protein homodimerization activity	Any process that decreases the frequency, rate or extent of protein homodimerization, interacting selectively with an identical protein to form a homodimer.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-09-11T11:15:40Z					biological_process											owl:Class	
GO:0006429	biolink:NamedThing	leucyl-tRNA aminoacylation	The process of coupling leucine to leucyl-tRNA, catalyzed by leucyl-tRNA synthetase. The leucyl-tRNA synthetase is a  class-I synthetase. The activated amino acid is transferred to the 2'-OH group of a leucine-accetping tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1905400	biolink:NamedThing	negative regulation of activated CD4-positive, alpha-beta T cell apoptotic process	Any process that stops, prevents or reduces the frequency, rate or extent of activated CD4-positive, alpha-beta T cell apoptotic process.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of activated CD4-positive, alpha-beta T lymphocyte apoptosis|downregulation of activated CD4-positive, alpha-beta T-cell apoptosis|negative regulation of activated CD4-positive, alpha-beta T-cell apoptosis|downregulation of activated CD4-positive, alpha-beta T-lymphocyte apoptosis|down regulation of activated CD4-positive, alpha-beta T cell apoptotic process|down regulation of activated CD4-positive, alpha-beta T-lymphocyte apoptosis|down regulation of activated CD4-positive, alpha-beta T lymphocyte apoptosis|inhibition of activated CD4-positive, alpha-beta T-cell apoptotic process|down-regulation of activated CD4-positive, alpha-beta T cell apoptotic process|down regulation of activated CD4-positive, alpha-beta T lymphocyte apoptotic process|down regulation of activated CD4-positive, alpha-beta T-cell apoptotic process|down-regulation of activated CD4-positive, alpha-beta T-lymphocyte apoptosis|downregulation of activated CD4-positive, alpha-beta T-cell apoptotic process|downregulation of activated CD4-positive, alpha-beta T lymphocyte apoptosis|negative regulation of activated CD4-positive, alpha-beta T lymphocyte apoptosis|down regulation of activated CD4-positive, alpha-beta T-lymphocyte apoptotic process|inhibition of activated CD4-positive, alpha-beta T-cell apoptosis|down-regulation of activated CD4-positive, alpha-beta T cell apoptosis|downregulation of activated CD4-positive, alpha-beta T lymphocyte apoptotic process|down-regulation of activated CD4-positive, alpha-beta T-cell apoptotic process|downregulation of activated CD4-positive, alpha-beta T cell apoptotic process|down regulation of activated CD4-positive, alpha-beta T-cell apoptosis|negative regulation of activated CD4-positive, alpha-beta T-lymphocyte apoptosis|inhibition of activated CD4-positive, alpha-beta T-lymphocyte apoptotic process|negative regulation of activated CD4-positive, alpha-beta T-lymphocyte apoptotic process|downregulation of activated CD4-positive, alpha-beta T cell apoptosis|inhibition of activated CD4-positive, alpha-beta T cell apoptosis|downregulation of activated CD4-positive, alpha-beta T-lymphocyte apoptotic process|negative regulation of activated CD4-positive, alpha-beta T lymphocyte apoptotic process|inhibition of activated CD4-positive, alpha-beta T cell apoptotic process|negative regulation of activated CD4-positive, alpha-beta T cell apoptosis|inhibition of activated CD4-positive, alpha-beta T lymphocyte apoptosis|down regulation of activated CD4-positive, alpha-beta T cell apoptosis|inhibition of activated CD4-positive, alpha-beta T-lymphocyte apoptosis|down-regulation of activated CD4-positive, alpha-beta T lymphocyte apoptotic process|inhibition of activated CD4-positive, alpha-beta T lymphocyte apoptotic process|negative regulation of activated CD4-positive, alpha-beta T-cell apoptotic process|down-regulation of activated CD4-positive, alpha-beta T-cell apoptosis|down-regulation of activated CD4-positive, alpha-beta T-lymphocyte apoptotic process							pga	2016-08-25T09:09:53Z					biological_process											owl:Class	
GO:1905399	biolink:NamedThing	regulation of activated CD4-positive, alpha-beta T cell apoptotic process	Any process that modulates the frequency, rate or extent of activated CD4-positive, alpha-beta T cell apoptotic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of activated CD4-positive, alpha-beta T-cell apoptosis|regulation of activated CD4-positive, alpha-beta T-lymphocyte apoptotic process|regulation of activated CD4-positive, alpha-beta T-cell apoptotic process|regulation of activated CD4-positive, alpha-beta T-lymphocyte apoptosis|regulation of activated CD4-positive, alpha-beta T cell apoptosis|regulation of activated CD4-positive, alpha-beta T lymphocyte apoptosis|regulation of activated CD4-positive, alpha-beta T lymphocyte apoptotic process							pga	2016-08-25T09:09:46Z					biological_process											owl:Class	
GO:0034054	biolink:NamedThing	suppression by symbiont of host defense-related programmed cell death	Any process in which a symbiont stops, prevents, or reduces the frequency, rate or extent of defense-related programmed cell death in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	down regulation by symbiont of host defense-related programmed cell death|negative regulation by symbiont of plant HR|inhibition of HR|negative regulation by symbiont of host defense-related PCD|negative regulation by symbiont of plant hypersensitive response|inhibition by symbiont of host defense-related PCD|down-regulation by symbiont of host defense-related programmed cell death|inhibition of hypersensitive response|negative regulation by symbiont of host defense-related programmed cell death|downregulation by symbiont of host defense-related programmed cell death|suppression of HR|inhibition by symbiont of host defense-related programmed cell death|inhibition of host defense-related PCD					Note that this term is used to annotate gene products of the symbiont. To annotate host gene products, consider the biological process term 'negative regulation of plant-type hypersensitive response ; GO:0034051'.								biological_process											owl:Class	
GO:0005152	biolink:NamedThing	interleukin-1 receptor antagonist activity	Blocks the binding of interleukin-1 to the interleukin-1 receptor complex.	tmpzr1t_l9r_go_relaxed.owl	IL-1ra													molecular_function											owl:Class	
GO:0009140	biolink:NamedThing	pyrimidine nucleoside diphosphate catabolic process	The chemical reactions and pathways resulting in the breakdown of pyrimidine nucleoside diphosphate, a compound consisting of a pyrimidine base linked to a ribose or deoxyribose sugar esterified with diphosphate on the sugar.	tmpzr1t_l9r_go_relaxed.owl	pyrimidine nucleoside diphosphate catabolism|pyrimidine nucleoside diphosphate degradation|pyrimidine nucleoside diphosphate breakdown													biological_process											owl:Class	
GO:0034111	biolink:NamedThing	negative regulation of homotypic cell-cell adhesion	Any process that stops, prevents, or reduces the frequency, rate, or extent of homotypic cell-cell adhesion.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0031498	biolink:NamedThing	chromatin disassembly	The controlled breakdown of chromatin from a higher order structure into its simpler subcomponents, DNA, histones, other proteins, and sometimes RNA.	tmpzr1t_l9r_go_relaxed.owl	chromatin maintenance													biological_process											owl:Class	
GO:0006333	biolink:NamedThing	chromatin assembly or disassembly	The formation or destruction of chromatin structures.	tmpzr1t_l9r_go_relaxed.owl	chromatin assembly/disassembly													biological_process											owl:Class	
GO:0019633	biolink:NamedThing	shikimate catabolic process	The chemical reactions and pathways resulting in the breakdown of shikimate, (3R,4S,5R)--3,4,5-trihydroxycyclohex-1-ene-1-carboxylate, the anion of shikimic acid.	tmpzr1t_l9r_go_relaxed.owl	shikimate degradation|shikimate breakdown|shikimate catabolism				MetaCyc:SHIKIMATEDEG-PWY									biological_process											owl:Class	
GO:0051889	biolink:NamedThing	negative regulation of timing of exogen	Any process that stops, prevents, or reduces the frequency, rate or extent of timing of exogen, the shedding phase of the hair cycle.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of exogen|down regulation of exogen|inhibition of exogen|down-regulation of exogen|downregulation of exogen													biological_process											owl:Class	
GO:0009129	biolink:NamedThing	pyrimidine nucleoside monophosphate metabolic process	The chemical reactions and pathways involving pyrimidine nucleoside monophosphate, a compound consisting of a pyrimidine base linked to a ribose or deoxyribose sugar esterified with phosphate on the sugar.	tmpzr1t_l9r_go_relaxed.owl	pyrimidine nucleoside monophosphate metabolism													biological_process											owl:Class	
GO:0075297	biolink:NamedThing	negative regulation of ascospore formation	Any process that stops, prevents, or reduces the frequency, rate or extent of ascospore formation, a process in which a sexual spore, named ascospore, from Ascomycete fungi was produced inside an ascus.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1904849	biolink:NamedThing	positive regulation of cell chemotaxis to fibroblast growth factor	Any process that activates or increases the frequency, rate or extent of cell chemotaxis to fibroblast growth factor.	tmpzr1t_l9r_go_relaxed.owl	up regulation of cell chemotaxis to fibroblast growth factor|activation of cell chemotaxis to fibroblast growth factor|up-regulation of cell chemotaxis to fibroblast growth factor|upregulation of cell chemotaxis to fibroblast growth factor							rph	2015-12-10T12:04:16Z					biological_process											owl:Class	
GO:0102395	biolink:NamedThing	9-cis-beta-carotene 9',10'-cleavage oxygenase activity	Catalysis of the reaction: 9-cis-beta-carotene + O2 <=> 9-cis-10'-apo-beta-carotenal + beta-ionone.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-13642|EC:1.13.11.68|RHEA:34399									molecular_function											owl:Class	
GO:0034033	biolink:NamedThing	purine nucleoside bisphosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of a purine nucleoside bisphosphate, a compound consisting of a purine base linked to a deoxyribose or ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar.	tmpzr1t_l9r_go_relaxed.owl	purine nucleoside bisphosphate formation|purine nucleoside bisphosphate biosynthesis|purine nucleoside bisphosphate synthesis|purine nucleoside bisphosphate anabolism													biological_process											owl:Class	
GO:0033788	biolink:NamedThing	leucoanthocyanidin reductase activity	Catalysis of the reaction: (2R,3S)-catechin + NADP+ + H2O = 2,3-trans-3,4-cis-leucocyanidin + NADPH + H+.	tmpzr1t_l9r_go_relaxed.owl	(2R,3S)-catechin:NADP+ 4-oxidoreductase activity|leucocyanidin reductase activity				MetaCyc:RXN-1484|EC:1.17.1.3|RHEA:10616									molecular_function											owl:Class	
GO:0140111	biolink:NamedThing	[choline trimethylamine-lyase]-activating enzyme activity	Catalyzes the activation of choline trimethylamine-lyase by generation of an organic free radical on a glycine residue via a homolytic cleavage of S-adenosyl-L-methionine (SAM).	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/14190			MetaCyc:RXN-16470			pg	2017-10-20T13:57:38Z					molecular_function											owl:Class	
GO:0110101	biolink:NamedThing	L-valine transmembrane import into vacuole	The directed movement of L-valine into the vacuole across the vacuolar membrane.	tmpzr1t_l9r_go_relaxed.owl								kmv	2018-03-14T19:56:06Z					biological_process											owl:Class	
GO:1903542	biolink:NamedThing	negative regulation of exosomal secretion	Any process that stops, prevents or reduces the frequency, rate or extent of exosomal secretion.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of extracellular vesicular exosome secretion|down regulation of extracellular vesicular exosome secretion|downregulation of exosomal protein secretion|negative regulation of secretion of exosome|down regulation of exosomal protein secretion|inhibition of exosomal protein secretion|down-regulation of secretion of exosome|down regulation of secretion of exosome|downregulation of extracellular vesicular exosome secretion|inhibition of exosomal secretion|down regulation of exosomal secretion|inhibition of secretion of exosome|negative regulation of exosomal protein secretion|negative regulation of extracellular vesicular exosome secretion|inhibition of exosomal secretory pathway|negative regulation of exosomal secretory pathway|down-regulation of exosomal secretory pathway|inhibition of extracellular vesicular exosome secretion|downregulation of secretion of exosome|down-regulation of exosomal secretion|downregulation of exosomal secretion|down-regulation of exosomal protein secretion|downregulation of exosomal secretory pathway|down regulation of exosomal secretory pathway							pga	2014-10-14T11:39:02Z					biological_process											owl:Class	
GO:0050859	biolink:NamedThing	negative regulation of B cell receptor signaling pathway	Any process that stops, prevents, or reduces the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a B cell.	tmpzr1t_l9r_go_relaxed.owl	inhibition of B cell receptor signaling pathway|down regulation of B cell receptor signaling pathway|downregulation of B cell receptor signaling pathway|negative regulation of B-cell receptor signalling pathway|negative regulation of B-cell receptor signaling pathway|negative regulation of B lymphocyte receptor signaling pathway|negative regulation of B-lymphocyte receptor signaling pathway|negative regulation of B lymphocyte receptor signalling pathway|down-regulation of B cell receptor signaling pathway|negative regulation of B-lymphocyte receptor signalling pathway|negative regulation of B cell receptor signalling pathway													biological_process											owl:Class	
GO:0033628	biolink:NamedThing	regulation of cell adhesion mediated by integrin	Any process that modulates the frequency, rate, or extent of cell adhesion mediated by integrin.	tmpzr1t_l9r_go_relaxed.owl	regulation of cell adhesion mediated by integrin complex													biological_process											owl:Class	
GO:0034278	biolink:NamedThing	stemar-13-ene synthase activity	Catalysis of the reaction: 9-alpha-copalyl diphosphate = stemar-13-ene + diphosphate.	tmpzr1t_l9r_go_relaxed.owl	9alpha-copalyl-diphosphate diphosphate-lyase (stemar-13-ene-forming) activity				EC:4.2.3.33|KEGG_REACTION:R09115|MetaCyc:RXN-4882|RHEA:25552									molecular_function											owl:Class	
GO:0140529	biolink:NamedThing	CMG complex assembly	The aggregation, arrangement and bonding together of a set of components to form the CMG complex, a protein complex that contains the GINS complex, Cdc45p, and the heterohexameric MCM complex, and that is involved in unwinding DNA during replication. The process begins when additional proteins (e.g. Cdc45 and Sld3) join the loaded, inactive double MCM hexamer at replication origins, and ends when Mcm10 triggers the separation of the Mcm2-7 double hexamers, forming two active CMG complexes.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/16570						pg	2020-10-12T16:42:17Z					biological_process											owl:Class	
GO:0015546	biolink:NamedThing	sulfathiazole transmembrane transporter activity	Enables the transfer of sulfathiazole from one side of a membrane to the other. Sulfathiazole is an antibacterial agent of the sulfonamide group.	tmpzr1t_l9r_go_relaxed.owl	bicyclomycin/sulfathiazole:hydrogen antiporter activity|sulphathiazole transporter activity													molecular_function											owl:Class	
GO:0036427	biolink:NamedThing	all-trans-undecaprenyl-phosphate mannosyltransferase activity	Catalysis of the reaction: all-trans-undecaprenyl phosphate + GDP-alpha-D-mannose = D-mannosyl undecaprenyl phosphate + GDP.	tmpzr1t_l9r_go_relaxed.owl					RHEA:28118			bf	2013-09-16T13:23:06Z					molecular_function											owl:Class	
GO:0047267	biolink:NamedThing	undecaprenyl-phosphate mannosyltransferase activity	Catalysis of the reaction: GDP-mannose + undecaprenyl phosphate = GDP + D-mannosyl-1-phosphoundecaprenol.	tmpzr1t_l9r_go_relaxed.owl	guanosine diphosphomannose-undecaprenyl phosphate mannosyltransferase activity|GDP mannose-undecaprenyl phosphate mannosyltransferase activity|GDP-D-mannose:lipid phosphate transmannosylase activity|GDP-mannose:undecaprenyl-phosphate D-mannosyltransferase activity				EC:2.4.1.54									molecular_function											owl:Class	
GO:0001868	biolink:NamedThing	regulation of complement activation, lectin pathway	Any process that modulates the frequency, rate or extent of the lectin pathway of complement activation.	tmpzr1t_l9r_go_relaxed.owl	regulation of complement cascade, lectin pathway													biological_process											owl:Class	
GO:1904939	biolink:NamedThing	regulation of DNA nucleotidylexotransferase activity	Any process that modulates the frequency, rate or extent of DNA nucleotidylexotransferase activity.	tmpzr1t_l9r_go_relaxed.owl	regulation of deoxyribonucleic acid nucleotidyltransferase activity|regulation of terminal deoxynucleotidyltransferase activity|regulation of terminal addition enzyme activity|regulation of nucleoside-triphosphate:DNA deoxynucleotidylexotransferase activity|regulation of terminal deoxyribonucleotidyltransferase activity|regulation of terminal deoxynucleotide transferase activity|regulation of deoxyribonucleic nucleotidyltransferase activity|regulation of terminal transferase activity|regulation of addase activity|regulation of deoxynucleotidyl terminal transferase activity|regulation of TdT							bc	2016-02-02T15:15:57Z					biological_process											owl:Class	
GO:1903812	biolink:NamedThing	L-serine import across plasma membrane	The directed movement of L-serine into a cell.	tmpzr1t_l9r_go_relaxed.owl	L-serine import into cell							mah	2015-01-16T14:36:29Z					biological_process											owl:Class	
GO:0015825	biolink:NamedThing	L-serine transport	The directed movement of L-serine, the L-enantiomer of 2-amino-3-hydroxypropanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	L-serine import							tb	2012-10-01T11:10:51Z			GO:0090479		biological_process											owl:Class	
GO:1903971	biolink:NamedThing	positive regulation of response to macrophage colony-stimulating factor	Any process that activates or increases the frequency, rate or extent of response to macrophage colony-stimulating factor.	tmpzr1t_l9r_go_relaxed.owl	activation of response to macrophage colony-stimulating factor stimulus|up-regulation of response to M-CSF|activation of response to M-CSF|positive regulation of response to macrophage colony-stimulating factor stimulus|up-regulation of response to macrophage colony-stimulating factor stimulus|up regulation of response to M-CSF|upregulation of response to macrophage colony-stimulating factor stimulus|positive regulation of response to M-CSF|activation of response to macrophage colony-stimulating factor|up regulation of response to macrophage colony-stimulating factor|up regulation of response to macrophage colony-stimulating factor stimulus|upregulation of response to M-CSF|up-regulation of response to macrophage colony-stimulating factor|upregulation of response to macrophage colony-stimulating factor							nc	2015-03-02T14:41:14Z					biological_process											owl:Class	
GO:0034585	biolink:NamedThing	21U-RNA metabolic process	The chemical reactions and pathways involving 21U-RNAs, a class of single-stranded RNA molecules of about 21 nucleotides in length characterized by a uridine 5'-monophosphate and a modified 3' end resistant to periodate degradation. 21U-RNAs are derived from distinct, autonomously expressed loci within the genome.	tmpzr1t_l9r_go_relaxed.owl	21U-RNA metabolism													biological_process											owl:Class	
GO:0042679	biolink:NamedThing	compound eye cone cell fate specification	The process in which a cell becomes capable of differentiating autonomously into a compound eye cone cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.	tmpzr1t_l9r_go_relaxed.owl												GO:0042678		biological_process											owl:Class	
GO:0072146	biolink:NamedThing	DCT cell fate commitment	The process in which the developmental fate of a cell becomes restricted such that it will develop into a distal convoluted tubule cell.	tmpzr1t_l9r_go_relaxed.owl	distal convoluted tubule cell fate commitment							mah	2010-02-24T01:59:04Z					biological_process											owl:Class	
GO:0070650	biolink:NamedThing	actin filament bundle distribution	Any cellular process that establishes the spatial arrangement of actin filament bundles within the cell.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-05-12T02:20:58Z					biological_process											owl:Class	
GO:0097363	biolink:NamedThing	protein O-GlcNAc transferase activity	Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + [protein]-L-serine = UDP + [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine, or UDP-N-acetyl-D-glucosamine + [protein]-L-threonine = UDP + [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine.	tmpzr1t_l9r_go_relaxed.owl	UDP-N-acetyl-D-glucosamine:protein-O-beta-N-acetyl-D-glucosaminyl transferase|OGTase|O-linked N-acetylglucosaminyltransferase|O-GlcNAc transferase				Reactome:R-HSA-9687828|EC:2.4.1.255			pr	2012-07-24T01:46:51Z					molecular_function											owl:Class	
GO:0019481	biolink:NamedThing	L-alanine catabolic process, by transamination	The chemical reactions and pathways resulting in the breakdown of L-alanine by transamination.	tmpzr1t_l9r_go_relaxed.owl	L-alanine degradation, by transamination|L-alanine breakdown, by transamination				MetaCyc:ALANINE-DEG3-PWY									biological_process											owl:Class	
GO:0009029	biolink:NamedThing	tetraacyldisaccharide 4'-kinase activity	Catalysis of the reaction: 2,3-bis(3-hydroxytetradecanoyl)-D-glucosaminyl-(1->6)-beta-D-2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate + ATP = ADP + 2 H(+) + lipid IV(a).	tmpzr1t_l9r_go_relaxed.owl	ATP:2,3,2',3'-tetrakis(3-hydroxytetradecanoyl)-D-glucosaminyl-beta-D-1,6-glucosaminyl-beta-phosphate 4'-O-phosphotransferase activity|lipid-A 4'-kinase activity				KEGG_REACTION:R04657|MetaCyc:TETRAACYLDISACC4KIN-RXN|RHEA:20700|EC:2.7.1.130									molecular_function											owl:Class	
GO:0010203	biolink:NamedThing	response to very low fluence red light stimulus	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a very low fluence red light stimulus. Red light is electromagnetic radiation of wavelength of 580-700nm. Very low fluence red light is defined in this case as short pulses of red light followed by darkness, providing light levels of less than 0.001 mmol/m2/sec.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0055122	biolink:NamedThing	response to very low light intensity stimulus	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a very low light intensity stimulus. A very low light intensity stimulus is defined as a level of electromagnetic radiation below 0.001 mmol/m2/sec.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0002294	biolink:NamedThing	CD4-positive, alpha-beta T cell differentiation involved in immune response	The process in which an antigenically naive CD4-positive, alpha-beta T cell acquires the specialized features of an effector, regulatory, or memory T cell as part of an immune response. Effector T cells include cells which provide T cell help or exhibit cytotoxicity towards other cells.	tmpzr1t_l9r_go_relaxed.owl	CD4-positive, alpha-beta T lymphocyte differentiation during immune response|CD4-positive, alpha-beta T-cell differentiation during immune response|CD4-positive, alpha-beta T cell development involved in immune response|CD4-positive, alpha-beta T-lymphocyte differentiation during immune response|CD4-positive, alpha-beta T cell differentiation during immune response					Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.								biological_process											owl:Class	
GO:0033084	biolink:NamedThing	regulation of immature T cell proliferation in thymus	Any process that modulates the frequency, rate or extent of immature T cell proliferation in the thymus.	tmpzr1t_l9r_go_relaxed.owl	regulation of thymocyte cell proliferation|regulation of thymic T cell proliferation|regulation of thymocyte proliferation					Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.								biological_process											owl:Class	
GO:2000452	biolink:NamedThing	regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation	Any process that modulates the frequency, rate or extent of CD8-positive, alpha-beta cytotoxic T cell extravasation.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-03-04T10:44:39Z					biological_process											owl:Class	
GO:0047872	biolink:NamedThing	dolichol O-acyltransferase activity	Catalysis of the reaction: palmitoyl-CoA + dolichol = CoA + dolichyl palmitate.	tmpzr1t_l9r_go_relaxed.owl	palmitoyl-CoA:dolichol O-palmitoyltransferase activity|acyl-CoA:dolichol acyltransferase activity				MetaCyc:DOLICHOL-O-ACYLTRANSFERASE-RXN|RHEA:16685|EC:2.3.1.123									molecular_function											owl:Class	
GO:1902225	biolink:NamedThing	negative regulation of acrosome reaction	Any process that stops, prevents or reduces the frequency, rate or extent of acrosome reaction.	tmpzr1t_l9r_go_relaxed.owl	downregulation of acrosome reaction|inhibition of acrosome reaction|down-regulation of acrosome reaction|down regulation of acrosome reaction							ae	2013-06-13T14:17:11Z					biological_process											owl:Class	
GO:0051415	biolink:NamedThing	microtubule nucleation by interphase microtubule organizing center	The 'de novo' formation of a microtubule by the interphase microtubule organizing center during interphase, the stage of cell cycle between successive rounds of chromosome segregation.	tmpzr1t_l9r_go_relaxed.owl	microtubule nucleation during interphase by interphase microtubule organizing center|microtubule nucleation during interphase by IMTOC|interphase microtubule organizing center-mediated microtubule nucleation during interphase|interphase microtubule nucleation by interphase microtubule organising centre|interphase microtubule nucleation by interphase microtubule organizing center|IMTOC-mediated microtubule nucleation during interphase													biological_process											owl:Class	
GO:0098539	biolink:NamedThing	cytoplasmic side of transport vesicle membrane	The side (leaflet) of the transport vesicle membrane that faces the cytoplasm.	tmpzr1t_l9r_go_relaxed.owl	external side of transport vesicle membrane							dos	2013-10-24T11:48:07Z					cellular_component											owl:Class	
GO:2001262	biolink:NamedThing	positive regulation of semaphorin-plexin signaling pathway	Any process that activates or increases the frequency, rate or extent of semaphorin-plexin signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of semaphorin-plexin signalling pathway							vk	2011-12-08T02:05:53Z					biological_process											owl:Class	
GO:2001260	biolink:NamedThing	regulation of semaphorin-plexin signaling pathway	Any process that modulates the frequency, rate or extent of semaphorin-plexin signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	regulation of semaphorin-plexin signalling pathway							vk	2011-12-08T02:05:41Z					biological_process											owl:Class	
GO:0006941	biolink:NamedThing	striated muscle contraction	A process in which force is generated within striated muscle tissue, resulting in the shortening of the muscle. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. Striated muscle is a type of muscle in which the repeating units (sarcomeres) of the contractile myofibrils are arranged in registry throughout the cell, resulting in transverse or oblique striations observable at the level of the light microscope.	tmpzr1t_l9r_go_relaxed.owl	sarcomeric muscle contraction													biological_process											owl:Class	
GO:0046952	biolink:NamedThing	ketone body catabolic process	The chemical reactions and pathways resulting in the breakdown of ketone bodies, any one of the three substances: acetoacetate, D-3-hydroxybutyrate (beta-hydroxybutyrate) or acetone. Ketone bodies can be used as an energy source as an alternative to glucose. Utilization of ketone bodies in peripheral tissues involves conversion of acetoacetate to acetoacetyl-CoA, which is then converted to two molecules of acetyl-CoA.	tmpzr1t_l9r_go_relaxed.owl	utilization of ketone bodies|ketone body degradation|ketolysis|ketone body catabolism|ketone body breakdown				Reactome:R-HSA-77108|MetaCyc:PWY66-368									biological_process											owl:Class	
GO:0140224	biolink:NamedThing	SLAC complex	A protein complex that regulates Arp2/3 complex-mediated actin nucleation.	tmpzr1t_l9r_go_relaxed.owl								pg	2018-05-29T09:54:08Z					cellular_component											owl:Class	
GO:0102490	biolink:NamedThing	8-oxo-dGTP phosphohydrolase activity	Catalysis of the reaction: 8-oxo-dGTP + 2 H2O <=> 8-oxo-dGMP + 2 hydrogenphosphate + 2 H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-14205|EC:3.6.1.5									molecular_function											owl:Class	
GO:0050768	biolink:NamedThing	negative regulation of neurogenesis	Any process that stops, prevents, or reduces the frequency, rate or extent of neurogenesis, the generation of cells within the nervous system.	tmpzr1t_l9r_go_relaxed.owl	down regulation of neurogenesis|downregulation of neurogenesis|inhibition of neurogenesis|down-regulation of neurogenesis													biological_process											owl:Class	
GO:0009091	biolink:NamedThing	homoserine catabolic process	The chemical reactions and pathways resulting in the breakdown of homoserine, alpha-amino-gamma-hydroxybutyric acid.	tmpzr1t_l9r_go_relaxed.owl	homoserine degradation|homoserine catabolism|homoserine breakdown				MetaCyc:HOMOCYSDEGR-PWY									biological_process											owl:Class	
GO:1900819	biolink:NamedThing	orlandin metabolic process	The chemical reactions and pathways involving orlandin.	tmpzr1t_l9r_go_relaxed.owl	orlandin metabolism							di	2012-06-04T10:14:55Z					biological_process											owl:Class	
GO:2000946	biolink:NamedThing	negative regulation of amylopectin catabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of amylopectin catabolic process.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of Amylopectin catabolism							tt	2011-08-01T02:15:27Z					biological_process											owl:Class	
GO:2000943	biolink:NamedThing	negative regulation of amylopectin metabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of amylopectin metabolic process.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of Amylopectin metabolism							tt	2011-08-01T02:10:32Z					biological_process											owl:Class	
GO:0007227	biolink:NamedThing	signal transduction downstream of smoothened	The series of molecular signals that are initiated by the transmembrane protein Smoothened. In the presence of a Hedgehog signaling molecule, the Patched protein no longer inhibits the activity of Smoothened, and Smoothened signals via the Hedgehog signaling complex to activate downstream components of the Hedgehog signaling pathway.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0009753	biolink:NamedThing	response to jasmonic acid	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a jasmonic acid stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to jasmonic acid stimulus													biological_process											owl:Class	
GO:0033322	biolink:NamedThing	homomethionine biosynthetic process	The chemical reactions and pathways resulting in the formation of homomethionine, a non-protein amino acid synthesized from methionine via chain elongation.	tmpzr1t_l9r_go_relaxed.owl	homomethionine biosynthesis|homomethionine synthesis|homomethionine formation|homomethionine anabolism				MetaCyc:PWY-1186									biological_process											owl:Class	
GO:0006776	biolink:NamedThing	vitamin A metabolic process	The chemical reactions and pathways involving any of the vitamin A compounds, retinol, retinal (retinaldehyde) and retinoic acid, all of which are derivatives of beta-carotene.	tmpzr1t_l9r_go_relaxed.owl	vitamin A metabolism													biological_process											owl:Class	
GO:0006775	biolink:NamedThing	fat-soluble vitamin metabolic process	The chemical reactions and pathways involving of any of a diverse group of vitamins that are soluble in organic solvents and relatively insoluble in water.	tmpzr1t_l9r_go_relaxed.owl	fat-soluble vitamin metabolism													biological_process											owl:Class	
GO:2000433	biolink:NamedThing	positive regulation of cytokinesis, actomyosin contractile ring assembly	Any process that activates or increases the frequency, rate or extent of cytokinesis, actomyosin contractile ring assembly.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of contractile ring assembly							vw	2011-03-03T12:18:43Z					biological_process											owl:Class	
GO:2000431	biolink:NamedThing	regulation of cytokinesis, actomyosin contractile ring assembly	Any process that modulates the frequency, rate or extent of cytokinesis, actomyosin contractile ring assembly.	tmpzr1t_l9r_go_relaxed.owl	regulation of contractile ring assembly							vw	2011-03-03T12:17:41Z					biological_process											owl:Class	
GO:0009794	biolink:NamedThing	regulation of mitotic cell cycle, embryonic	Any process that modulates the frequency, rate or extent of replication and segregation of genetic material in the embryo.	tmpzr1t_l9r_go_relaxed.owl	embryonic mitotic cell cycle modulation|embryonic mitotic cell cycle regulator|embryonic mitotic cell cycle regulation|regulation of embryonic mitotic cell cycle progression|modulation of embryonic mitotic cell cycle progression|regulation of embryonic mitotic cell cycle|regulation of progression through embryonic mitotic cell cycle													biological_process											owl:Class	
GO:0045656	biolink:NamedThing	negative regulation of monocyte differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of monocyte differentiation.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of monocyte differentiation|down regulation of monocyte differentiation|downregulation of monocyte differentiation|inhibition of monocyte differentiation													biological_process											owl:Class	
GO:0018106	biolink:NamedThing	peptidyl-histidine phosphorylation	The phosphorylation of peptidyl-histidine to form peptidyl-1'-phospho-L-histidine (otherwise known as tau-phosphohistidine, tele-phosphohistidine) or peptidyl-3'-phospho-L-histidine (otherwise known as pi-phosphohistidine, pros-phosphohistidine).	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0036|RESID:AA0035									biological_process											owl:Class	
GO:0102216	biolink:NamedThing	maltodextrin water dikinase	Catalysis of the reaction: ATP + H2O + a maltodextrin = AMP + hydrogenphosphate + a 6-phosphogluco-maltodextrin.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-12201|EC:2.7.9.4									molecular_function											owl:Class	
GO:0016781	biolink:NamedThing	phosphotransferase activity, paired acceptors	Catalysis of the transfer of two phosphate groups from a donor, such as ATP, to two different acceptors.	tmpzr1t_l9r_go_relaxed.owl					EC:2.7.9.-									molecular_function											owl:Class	
GO:0002879	biolink:NamedThing	positive regulation of acute inflammatory response to non-antigenic stimulus	Any process that activates or increases the frequency, rate, or extent of an acute inflammatory response to a non-antigenic stimulus.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of acute inflammatory response to non-antigenic stimulus|activation of acute inflammatory response to non-antigenic stimulus|upregulation of acute inflammatory response to non-antigenic stimulus|stimulation of acute inflammatory response to non-antigenic stimulus|up regulation of acute inflammatory response to non-antigenic stimulus													biological_process											owl:Class	
GO:0007485	biolink:NamedThing	imaginal disc-derived male genitalia development	The process whose specific outcome is the progression of the male genitalia over time, from formation as part of the genital disc to the mature structure. An example of this is found in Drosophila melanogaster.	tmpzr1t_l9r_go_relaxed.owl	male genital development													biological_process											owl:Class	
GO:0007484	biolink:NamedThing	imaginal disc-derived genitalia development	The process whose specific outcome is the progression of the genitalia over time, from formation as part of the genital disc to the mature structure. An example of this is found in Drosophila melanogaster.	tmpzr1t_l9r_go_relaxed.owl	genital development													biological_process											owl:Class	
GO:0019042	biolink:NamedThing	viral latency	The process by which, after initial infection, a virus lies dormant within a cell and viral production ceases. The process ends when the virus switches from latency and starts to replicate.	tmpzr1t_l9r_go_relaxed.owl	viral dormancy|latent virus infection|phage lysogeny											GO:0075710|GO:0030069		biological_process											owl:Class	
GO:0018265	biolink:NamedThing	GPI anchor biosynthetic process via N-asparaginyl-glycosylphosphatidylinositolethanolamine	The chemical reactions and pathways resulting in the formation of a C-terminal peptidyl-asparagine ethanolamide-linked glycosylphosphatidylinositol (GPI) anchor following hydrolysis of a asparaginyl-peptide bond in the carboxy-terminal region of a membrane-associated protein.	tmpzr1t_l9r_go_relaxed.owl	GPI anchor synthesis via N-asparaginyl-glycosylphosphatidylinositolethanolamine|GPI anchor anabolism via N-asparaginyl-glycosylphosphatidylinositolethanolamine|GPI anchor formation via N-asparaginyl-glycosylphosphatidylinositolethanolamine				RESID:AA0158									biological_process											owl:Class	
GO:0034349	biolink:NamedThing	glial cell apoptotic process	Any apoptotic process in a glial cell, a non-neuronal cell of the nervous system.	tmpzr1t_l9r_go_relaxed.owl	apoptosis of glia|programmed cell death of glial cells by apoptosis|glia programmed cell death by apoptosis|glia apoptosis|programmed cell death, glia|programmed cell death, glial cells|glial cell apoptosis|programmed cell death of glia by apoptosis|apoptosis of glial cells|glial cell programmed cell death by apoptosis													biological_process											owl:Class	
GO:1904234	biolink:NamedThing	positive regulation of aconitate hydratase activity	Any process that activates or increases the frequency, rate or extent of aconitate hydratase activity.	tmpzr1t_l9r_go_relaxed.owl	activation of citrate(isocitrate) hydro-lyase (cis-aconitate-forming)|activation of aconitate hydratase activity|up regulation of aconitase activity|upregulation of aconitase activity|activation of citrate(isocitrate) hydro-lyase activity|up regulation of aconitate hydratase activity|upregulation of aconitate hydratase activity|up regulation of citrate(isocitrate) hydro-lyase activity|positive regulation of citrate(isocitrate) hydro-lyase activity|up-regulation of citrate(isocitrate) hydro-lyase activity|upregulation of cis-aconitase activity|up regulation of citrate(isocitrate) hydro-lyase (cis-aconitate-forming)|up-regulation of aconitase activity|up-regulation of aconitate hydratase activity|activation of aconitase activity|up regulation of cis-aconitase activity|up-regulation of citrate(isocitrate) hydro-lyase (cis-aconitate-forming)|positive regulation of citrate(isocitrate) hydro-lyase (cis-aconitate-forming)|positive regulation of aconitase activity|upregulation of citrate(isocitrate) hydro-lyase (cis-aconitate-forming)|activation of cis-aconitase activity|upregulation of citrate(isocitrate) hydro-lyase activity|up-regulation of cis-aconitase activity|positive regulation of cis-aconitase activity							rl	2015-05-15T09:55:29Z					biological_process											owl:Class	
GO:1904232	biolink:NamedThing	regulation of aconitate hydratase activity	Any process that modulates the frequency, rate or extent of aconitate hydratase activity.	tmpzr1t_l9r_go_relaxed.owl	regulation of aconitase activity|regulation of citrate(isocitrate) hydro-lyase (cis-aconitate-forming)|regulation of citrate(isocitrate) hydro-lyase activity|regulation of citrate hydro-lyase activity|regulation of cis-aconitase activity							rl	2015-05-15T09:55:17Z					biological_process											owl:Class	
GO:0048579	biolink:NamedThing	negative regulation of long-day photoperiodism, flowering	Any process that stops, prevents or reduces long-day photoperiodism, where the response associated with the photoperiodism is flowering. Flowering is defined by the switch from the vegetative to the reproductive phase.	tmpzr1t_l9r_go_relaxed.owl	downregulation of long-day photoperiodism, flowering|down regulation of long-day photoperiodism, flowering|down-regulation of long-day photoperiodism, flowering|inhibition of long-day photoperiodism, flowering													biological_process											owl:Class	
GO:0015628	biolink:NamedThing	protein secretion by the type II secretion system	The process in which proteins are secreted across the outer membrane of Gram-negative bacteria by the type II secretion system. Proteins using this pathway are first translocated across the cytoplasmic membrane via the Sec or Tat pathways.	tmpzr1t_l9r_go_relaxed.owl	protein secretion by the general secretion pathway|protein secretion by the general secretory pathway|type II protein secretion system|protein secretion by the type II protein secretion system|protein secretion by the T2SS|protein secretion by the T2S					Note that this term represents an activity and not a cellular structure. Consider also annotating to the cellular component term 'type II protein secretion system complex ; GO:0015627'. This process refers specifically to secretion across the outer membrane. For components of the Sec and Tat pathways, consider annotating to 'protein transport by the Sec complex ; GO:0043952' and 'protein transport by the Tat complex ; GO:0043953'. Note that this term is used for annotation of proteins that compose the secretion complex but not the proteins being secreted.								biological_process											owl:Class	
GO:0030680	biolink:NamedThing	dimeric ribonuclease P complex	A ribonuclease P complex that contains a single RNA molecule that is necessary and usually sufficient for catalysis, and a single protein molecule. Examples of this complex are found in Bacterial species.	tmpzr1t_l9r_go_relaxed.owl	dimeric RNase P complex													cellular_component											owl:Class	
GO:2000962	biolink:NamedThing	positive regulation of cellooligosaccharide metabolic process	Any process that activates or increases the frequency, rate or extent of cellooligosaccharide metabolic process.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of cellooligosaccharide metabolism							tt	2011-08-01T02:26:02Z					biological_process											owl:Class	
GO:0019884	biolink:NamedThing	antigen processing and presentation of exogenous antigen	The process in which an antigen-presenting cell expresses antigen (peptide or lipid) of exogenous origin on its cell surface in association with an MHC protein complex.	tmpzr1t_l9r_go_relaxed.owl	antigen presentation, exogenous antigen													biological_process											owl:Class	
GO:0033301	biolink:NamedThing	cell cycle comprising mitosis without cytokinesis	A mitotic cell cycle in which mitosis is completed but cytokinesis does not occur, resulting in a cell containing multiple nuclei each with a chromosomal complement of the original ploidy (usually 2N).	tmpzr1t_l9r_go_relaxed.owl						Note that this term should be used for naturally occurring instances of mitosis without cytokinesis, e.g. in the tapetum of flowers and in a number of lower eukaryotes; it should not be used for abnormal events such as may occur in cancers.								biological_process											owl:Class	
GO:0001543	biolink:NamedThing	ovarian follicle rupture	Disruption of theca cell layer releasing follicular fluid and/or the oocyte.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:2000206	biolink:NamedThing	regulation of ribosomal small subunit export from nucleus	Any process that modulates the frequency, rate or extent of ribosomal small subunit export from nucleus.	tmpzr1t_l9r_go_relaxed.owl	regulation of ribosomal small subunit export from cell nucleus|regulation of ribosomal small subunit transport from nucleus to cytoplasm|regulation of 40S ribosomal subunit export from nucleus|regulation of ribosomal small subunit-nucleus export|regulation of 30S ribosomal subunit export from nucleus|regulation of ribosomal small subunit export out of nucleus							mah	2010-10-26T10:54:09Z					biological_process											owl:Class	
GO:0071107	biolink:NamedThing	response to parathyroid hormone	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a parathyroid hormone stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to parathyroid hormone stimulus							mah	2009-11-12T10:58:45Z					biological_process											owl:Class	
GO:0009725	biolink:NamedThing	response to hormone	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hormone stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to hormone stimulus|growth regulator													biological_process											owl:Class	
GO:0009355	biolink:NamedThing	DNA polymerase V complex	A DNA polymerase complex that contains two UmuD' and one UmuC subunits, and acts in translesion DNA synthesis.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0050525	biolink:NamedThing	cutinase activity	Catalysis of the reaction: cutin + H2O = cutin monomers.	tmpzr1t_l9r_go_relaxed.owl	cutin hydrolase activity				EC:3.1.1.74|MetaCyc:3.1.1.74-RXN									molecular_function											owl:Class	
GO:0052562	biolink:NamedThing	suppression by symbiont of host immune response	Any process in which a symbiont stops, prevents, or reduces the frequency, rate or extent of the immune response of the host organism; the immune response is any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	downregulation by symbiont of host immune response|negative regulation by symbiont of host immune response|down-regulation by symbiont of host immune response|inhibition by symbiont of host immune response|down regulation by symbiont of host immune response|negative regulation by organism of immune response of other organism involved in symbiotic interaction											GO:0052561		biological_process											owl:Class	
GO:0120125	biolink:NamedThing	PNGase complex	A protein complex responsible for the catalysis of the reaction: 4-N-(N-acetyl-D-glucosaminyl)-protein + H2O = N-acetyl-beta-D-glucosaminylamine + peptide L-aspartate. This reaction is the hydrolysis of an N4-(acetyl-beta-D-glucosaminyl)asparagine residue in which the N-acetyl-D-glucosamine residue may be further glycosylated, to yield a (substituted) N-acetyl-beta-D-glucosaminylamine and the peptide containing an aspartic residue.	tmpzr1t_l9r_go_relaxed.owl								krc	2018-02-12T16:31:57Z					cellular_component											owl:Class	
GO:0061210	biolink:NamedThing	cell-cell signaling involved in mesonephros development	Any process that mediates the transfer of information from one cell to another and contributes to the progression of the mesonephros over time, from its formation to the mature organ.	tmpzr1t_l9r_go_relaxed.owl	cell-cell signalling involved in mesonephros development							dph	2010-08-17T03:24:08Z					biological_process											owl:Class	
GO:0035661	biolink:NamedThing	MyD88-dependent toll-like receptor 2 signaling pathway	Any series of molecular signals generated as a consequence of binding to a toll-like 2 receptor where the MyD88 adaptor molecule mediates transduction of the signal. Toll-like 2 receptors are pattern recognition receptors that bind microbial pattern motifs to initiate an innate immune response.	tmpzr1t_l9r_go_relaxed.owl	MyD88-dependent TLR2 signaling pathway|MyD88-dependent toll-like receptor 2 signalling pathway							bf	2011-02-01T10:11:01Z					biological_process											owl:Class	
GO:1902008	biolink:NamedThing	negative regulation of toxin transport	Any process that stops, prevents or reduces the frequency, rate or extent of toxin transport.	tmpzr1t_l9r_go_relaxed.owl	downregulation of toxin transport|down regulation of toxin transport|down-regulation of toxin transport|inhibition of toxin transport							dph	2013-03-22T12:54:00Z					biological_process											owl:Class	
GO:0046815	biolink:NamedThing	genome retention in viral capsid	Any process in which the viral genome is retained within the capsid during genome cleavage and packaging.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1901808	biolink:NamedThing	capsanthin catabolic process	The chemical reactions and pathways resulting in the breakdown of capsanthin.	tmpzr1t_l9r_go_relaxed.owl	capsanthin breakdown|capsanthin catabolism|capsanthin degradation							yaf	2013-01-22T10:21:46Z					biological_process											owl:Class	
GO:1901807	biolink:NamedThing	capsanthin metabolic process	The chemical reactions and pathways involving capsanthin.	tmpzr1t_l9r_go_relaxed.owl	capsanthin metabolism							yaf	2013-01-22T10:21:39Z					biological_process											owl:Class	
GO:1902644	biolink:NamedThing	tertiary alcohol metabolic process	The chemical reactions and pathways involving tertiary alcohol.	tmpzr1t_l9r_go_relaxed.owl	tertiary alcohol metabolism							tt	2014-01-21T17:53:53Z					biological_process											owl:Class	
GO:0018175	biolink:NamedThing	protein nucleotidylation	The addition of a nucleotide to a protein amino acid.	tmpzr1t_l9r_go_relaxed.owl	protein amino acid nucleotidylation													biological_process											owl:Class	
GO:0046818	biolink:NamedThing	dense nuclear body	A location in the host cell nucleus where viral proteins colocalize late in infection prior to the onset of viral DNA synthesis. More than one site can be present simultaneously.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0036279	biolink:NamedThing	positive regulation of protein export from nucleus in response to glucose starvation	Any process that activates or increases the frequency, rate or extent of directed movement of proteins from the nucleus into the cytoplasm in response to deprivation of glucose.	tmpzr1t_l9r_go_relaxed.owl								bf	2012-07-11T11:05:20Z					biological_process											owl:Class	
GO:0046827	biolink:NamedThing	positive regulation of protein export from nucleus	Any process that activates or increases the frequency, rate or extent of directed movement of proteins from the nucleus into the cytoplasm.	tmpzr1t_l9r_go_relaxed.owl	upregulation of protein export from nucleus|up regulation of protein export from nucleus|activation of protein export from nucleus|positive regulation of protein-nucleus export|up-regulation of protein export from nucleus|stimulation of protein export from nucleus|positive regulation of protein transport from nucleus to cytoplasm|positive regulation of protein export out of nucleus|positive regulation of protein export from cell nucleus													biological_process											owl:Class	
GO:0051664	biolink:NamedThing	nuclear pore localization	Any process in which nuclear pores are transported to, or maintained in, a specific location.	tmpzr1t_l9r_go_relaxed.owl	establishment and maintenance of nuclear pore localization|nuclear pore localisation|nuclear pore distribution|positioning of nuclear pores											GO:0031081		biological_process											owl:Class	
GO:0001884	biolink:NamedThing	pyrimidine nucleoside binding	Binding to a pyrimidine nucleoside, a compound consisting of a pyrimidine base linked either to ribose or deoxyribose.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0071064	biolink:NamedThing	alphaE-beta7 integrin-E-cadherin complex	A protein complex that consists of an alphaE-beta7 integrin complex bound to E-cadherin.	tmpzr1t_l9r_go_relaxed.owl	ITGAE-ITGB7-CDH1 complex							mah	2009-11-03T04:03:37Z					cellular_component											owl:Class	
GO:0060502	biolink:NamedThing	epithelial cell proliferation involved in lung morphogenesis	The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population that contributes to the shaping of the lung.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0016875	biolink:NamedThing	ligase activity, forming carbon-oxygen bonds	Catalysis of the joining of two molecules via a carbon-oxygen bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.	tmpzr1t_l9r_go_relaxed.owl					EC:6.1.-.-									molecular_function											owl:Class	
GO:0007462	biolink:NamedThing	R1/R6 cell fate commitment	The process in which the R1/R6 photoreceptors commit to their cell fate. R1 and R6 are paired photoreceptors which contribute the outer rhabdomeres.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0001752	biolink:NamedThing	compound eye photoreceptor fate commitment	The process in which the developmental fate of a cell becomes restricted such that it will develop into a compound eye photoreceptor cell. A photoreceptor cell is a cell that responds to incident electromagnetic radiation. Different classes of photoreceptor have different spectral sensitivities and express different photosensitive pigments.	tmpzr1t_l9r_go_relaxed.owl												GO:0007459		biological_process											owl:Class	
GO:0035709	biolink:NamedThing	memory T cell activation	The change in morphology and behavior of a memory T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-03-02T03:03:02Z					biological_process											owl:Class	
GO:0050615	biolink:NamedThing	1,2-dihydrovomilenine reductase activity	Catalysis of the reaction: 17-O-acetylnorajmaline + NADP(+) = 1,2-dihydrovomilenine + H(+) + NADPH.	tmpzr1t_l9r_go_relaxed.owl	17-O-acetylnorajmaline:NADP+ oxidoreductase activity				EC:1.3.1.73|MetaCyc:1.3.1.73-RXN|RHEA:12320|KEGG_REACTION:R05879									molecular_function											owl:Class	
GO:0050529	biolink:NamedThing	polyneuridine-aldehyde esterase activity	Catalysis of the reaction: H(2)O + polyneuridine aldehyde = 16-epivellosimine + CO(2) + methanol.	tmpzr1t_l9r_go_relaxed.owl	PNAE activity|polyneuridine aldehyde hydrolase (decarboxylating)|polyneuridine aldehyde esterase activity				KEGG_REACTION:R05825|RHEA:17501|EC:3.1.1.78|MetaCyc:3.1.1.78-RXN									molecular_function											owl:Class	
GO:0045969	biolink:NamedThing	positive regulation of juvenile hormone biosynthetic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of juvenile hormone.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of juvenile hormone formation|up-regulation of juvenile hormone biosynthetic process|positive regulation of juvenile hormone anabolism|up regulation of juvenile hormone biosynthetic process|positive regulation of juvenile hormone synthesis|positive regulation of juvenile hormone biosynthesis|upregulation of juvenile hormone biosynthetic process|stimulation of juvenile hormone biosynthetic process|activation of juvenile hormone biosynthetic process													biological_process											owl:Class	
GO:0044539	biolink:NamedThing	long-chain fatty acid import into cell	The directed movement of a long-chain fatty acid from outside of a cell into a cell. This may occur via transport across the plasma membrane or via endocytosis. A long-chain fatty acid is a fatty acid with a chain length between C13 and C22.	tmpzr1t_l9r_go_relaxed.owl	long-chain fatty acid import|long-chain fatty acid uptake							jl	2012-03-21T03:34:04Z					biological_process											owl:Class	
GO:0001929	biolink:NamedThing	negative regulation of exocyst assembly	Any process that stops, prevents, or reduces the rate or extent of exocyst assembly.	tmpzr1t_l9r_go_relaxed.owl	inhibition of exocyst assembly|downregulation of exocyst assembly|down regulation of exocyst assembly|down-regulation of exocyst assembly													biological_process											owl:Class	
GO:0046302	biolink:NamedThing	2-chloro-N-isopropylacetanilide catabolic process	The chemical reactions and pathways resulting in the breakdown of 2-chloro-N-isopropylacetanilide, an acylanide herbicide widely used to protect corn, onion, cabbage, rose bushes, and ornamental plants.	tmpzr1t_l9r_go_relaxed.owl	2-chloro-N-isopropylacetanilide degradation|2-chloro-N-isopropylacetanilide breakdown|2-chloro-N-isopropylacetanilide catabolism													biological_process											owl:Class	
GO:1900139	biolink:NamedThing	negative regulation of arachidonic acid secretion	Any process that stops, prevents or reduces the frequency, rate or extent of arachidonic acid secretion.	tmpzr1t_l9r_go_relaxed.owl	inhibition of arachidonic acid secretion|down-regulation of arachidonic acid secretion|down regulation of arachidonic acid secretion|downregulation of arachidonic acid secretion							rph	2012-03-01T09:21:19Z					biological_process											owl:Class	
GO:1901724	biolink:NamedThing	positive regulation of cell proliferation involved in kidney development	Any process that activates or increases the frequency, rate or extent of cell proliferation involved in kidney development.	tmpzr1t_l9r_go_relaxed.owl	up regulation of cell proliferation involved in kidney development|up-regulation of cell proliferation involved in kidney development|upregulation of cell proliferation involved in kidney development|activation of cell proliferation involved in kidney development							krc	2012-12-27T19:30:40Z					biological_process											owl:Class	
GO:0004473	biolink:NamedThing	malate dehydrogenase (decarboxylating) (NADP+) activity	Catalysis of the reaction: (S)-malate + NADP+ = pyruvate + CO2 + NADPH + H+.	tmpzr1t_l9r_go_relaxed.owl	NADP-linked decarboxylating malic enzyme|NADP-malic enzyme activity|NADP-specific malic enzyme|'malic' enzyme|(S)-malate:NADP+ oxidoreductase (oxaloacetate-decarboxylating)|malate dehydrogenase (decarboxylating, NADP)|NADP-specific malate dehydrogenase activity|malate dehydrogenase (NADP, decarboxylating)|L-malate:NADP oxidoreductase activity				Reactome:R-HSA-9012036|RHEA:18253|Reactome:R-HSA-9012349|KEGG_REACTION:R00216|MetaCyc:MALIC-NADP-RXN|EC:1.1.1.40	For decarboxylation of oxaloacetate (the second substrate listed in EC:1.1.1.40), see 'oxaloacetate decarboxylase activity ; GO:0008948'.								molecular_function											owl:Class	
GO:0004470	biolink:NamedThing	malic enzyme activity	Catalysis of the oxidative decarboxylation of malate with the concomitant production of pyruvate.	tmpzr1t_l9r_go_relaxed.owl	pyruvic-malic carboxylase activity													molecular_function											owl:Class	
GO:1902784	biolink:NamedThing	response to undecane	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an undecane stimulus.	tmpzr1t_l9r_go_relaxed.owl								tt	2014-03-21T13:39:06Z					biological_process											owl:Class	
GO:0000440	biolink:NamedThing	core TFIIH complex portion of NEF3 complex	The core TFIIH complex when it is part of the nucleotide-excision repair factor 3 (NEF3).	tmpzr1t_l9r_go_relaxed.owl	SSL2-core TFIIH complex portion of NEF3 complex											GO:0000442		cellular_component											owl:Class	
GO:0044571	biolink:NamedThing	[2Fe-2S] cluster assembly	The incorporation of two iron atoms and two sulfur atoms into an iron-sulfur cluster.	tmpzr1t_l9r_go_relaxed.owl	2Fe-2S cluster assembly|[2Fe-2S] cluster biosynthetic process							jl	2012-04-18T03:06:30Z					biological_process											owl:Class	
GO:0097161	biolink:NamedThing	DH domain binding	Binding to a DH (Dbl homology) domain of a protein. The DH domain contains three structurally conserved regions separated by more variable regions. It is composed of 11 alpha helices that are folded into a flattened, elongated alpha-helix bundle in which two of the three conserved regions, conserved region 1 (CR1) and conserved region 3 (CR3), are exposed near the centre of one surface. CR1 and CR3, together with a part of alpha-6 and the DH/PH (pleckstrin homology) junction site, constitute the Rho GTPase interacting pocket.	tmpzr1t_l9r_go_relaxed.owl								pr	2011-09-27T10:06:09Z					molecular_function											owl:Class	
GO:1904290	biolink:NamedThing	negative regulation of mitotic DNA damage checkpoint	Any process that stops, prevents or reduces the frequency, rate or extent of mitotic DNA damage checkpoint.	tmpzr1t_l9r_go_relaxed.owl	downregulation of mitotic DNA damage checkpoint|down regulation of mitotic DNA damage checkpoint|down-regulation of mitotic DNA damage checkpoint|inhibition of mitotic DNA damage checkpoint							kmv	2015-06-09T13:03:17Z					biological_process											owl:Class	
GO:1905182	biolink:NamedThing	positive regulation of urease activity	Any process that activates or increases the frequency, rate or extent of urease activity.	tmpzr1t_l9r_go_relaxed.owl	activation of urea amidohydrolase activity|upregulation of urea amidohydrolase activity|up-regulation of urease activity|up-regulation of urea amidohydrolase activity|up regulation of urease activity|upregulation of urease activity|up regulation of urea amidohydrolase activity|positive regulation of urea amidohydrolase activity|activation of urease activity							tb	2016-05-09T23:16:03Z					biological_process											owl:Class	
GO:0097584	biolink:NamedThing	dolichyl-phosphate-mannose-protein mannosyltransferase Pmt5p-Pmt2p dimer complex	A protein dimer complex that possesses dolichyl-phosphate-mannose-protein mannosyltransferase activity and, in S. cerevisiae, is composed of Pmt5p-Pmt2p.	tmpzr1t_l9r_go_relaxed.owl	Pmt5p-Pmt2p complex							pr	2014-03-02T18:17:22Z					cellular_component											owl:Class	
GO:0102067	biolink:NamedThing	geranylgeranyl diphosphate reductase activity	Catalysis of the reaction: (E)-3,7,11,15-tetramethylhexadec-2-en-1-yl diphosphate + 3 NADP <=> 2-trans,6-trans,10-trans-geranylgeranyl diphosphate + 3 NADPH + 3 H+.	tmpzr1t_l9r_go_relaxed.owl					EC:1.3.1.83|RHEA:26229|MetaCyc:RXN-10625									molecular_function											owl:Class	
GO:0005094	biolink:NamedThing	Rho GDP-dissociation inhibitor activity	Prevents the dissociation of GDP from the small GTPase Rho, thereby preventing GTP from binding.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0014825	biolink:NamedThing	stomach fundus smooth muscle contraction	A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the fundus of stomach. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The fundus is the portion of the stomach that lies above the cardiac notch.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0014847	biolink:NamedThing	proximal stomach smooth muscle contraction	A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the proximal stomach. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The proximal stomach, composed of the fundus and upper body, shows low frequency, sustained tonic contractions that are responsible for generating a basal pressure within the stomach.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0003196	biolink:NamedThing	ventriculo bulbo valve formation	The developmental process pertaining to the initial formation of the ventriculo bulbo valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-10-08T01:16:02Z					biological_process											owl:Class	
GO:0035667	biolink:NamedThing	TRIF-dependent toll-like receptor 4 signaling pathway	Any series of molecular signals generated as a consequence of binding to a toll-like 4 receptor where the TRIF adaptor mediates transduction of the signal. Toll-like 4 receptors are pattern recognition receptors that bind bacterial lipopolysaccharide (LPS) to initiate an innate immune response.	tmpzr1t_l9r_go_relaxed.owl	TRIF-dependent toll-like receptor 4 signalling pathway|Toll/IL-1 receptor (TIR) domain-containing adaptor-dependent TLR4 signaling pathway|TRIF-dependent TLR4 signaling pathway							bf	2011-02-01T02:37:25Z					biological_process											owl:Class	
GO:0046046	biolink:NamedThing	TTP metabolic process	The chemical reactions and pathways involving TTP, ribosylthymine triphosphate.	tmpzr1t_l9r_go_relaxed.owl	TTP metabolism													biological_process											owl:Class	
GO:1904999	biolink:NamedThing	positive regulation of leukocyte adhesion to arterial endothelial cell	Any process that activates or increases the frequency, rate or extent of leukocyte adhesion to arterial endothelial cell.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of leukocyte adhesion to arterial endothelial cell|up regulation of leukocyte adhesion to arterial endothelial cell|upregulation of leukocyte adhesion to arterial endothelial cell|activation of leukocyte adhesion to arterial endothelial cell							bc	2016-03-01T11:05:05Z					biological_process											owl:Class	
GO:1904997	biolink:NamedThing	regulation of leukocyte adhesion to arterial endothelial cell	Any process that modulates the frequency, rate or extent of leukocyte adhesion to arterial endothelial cell.	tmpzr1t_l9r_go_relaxed.owl								bc	2016-03-01T11:04:49Z					biological_process											owl:Class	
GO:0051826	biolink:NamedThing	negative regulation of synapse structural plasticity	Any process that stops, prevents, or reduces the frequency, rate or extent of synapse structural plasticity.	tmpzr1t_l9r_go_relaxed.owl	downregulation of synapse structural plasticity|inhibition of synapse structural plasticity|down regulation of synapse structural plasticity|down-regulation of synapse structural plasticity													biological_process											owl:Class	
GO:0051823	biolink:NamedThing	regulation of synapse structural plasticity	Any process that modulates the frequency, rate or extent of synapse structural plasticity. Synapse structural plasticity is a type of cytoskeletal remodeling; this remodeling is induced by stimuli that can lead to long term potentiation and it can be activity-dependent or -independent. Examples of cytoskeletal changes include the formation of new spines and increase in spine size; this can be accompanied by the insertion of greater numbers of glutamate (or other neurotransmitter) receptors into the post-synaptic membrane.	tmpzr1t_l9r_go_relaxed.owl	regulation of synaptic structural plasticity													biological_process											owl:Class	
GO:0021736	biolink:NamedThing	globose nucleus development	The process whose specific outcome is the progression of the globose nucleus over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0005046	biolink:NamedThing	KDEL sequence binding	Binding to a KDEL sequence, the C terminus tetrapeptide sequence Lys-Asp-Glu-Leu found in proteins that are to be retained in the endoplasmic reticulum.	tmpzr1t_l9r_go_relaxed.owl	KDEL receptor activity													molecular_function											owl:Class	
GO:0046923	biolink:NamedThing	ER retention sequence binding	Binding to an endoplasmic reticulum (ER) retention sequence, a specific peptide sequence that ensures a protein is retained within the ER.	tmpzr1t_l9r_go_relaxed.owl	endoplasmic reticulum retention sequence binding													molecular_function											owl:Class	
GO:1900199	biolink:NamedThing	positive regulation of protein export from nucleus during meiotic anaphase II	Any process that activates or increases the frequency, rate or extent of directed movement of proteins from the nucleus into the cytoplasm, during anaphase occurring as part of meiosis II.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of protein export from nucleus involved in meiotic anaphase II							pr	2012-03-20T06:35:19Z					biological_process											owl:Class	
GO:0060258	biolink:NamedThing	negative regulation of filamentous growth	Any process that decreases the frequency, rate or extent of the process in which a multicellular organism or a group of unicellular organisms grow in a threadlike, filamentous shape.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0009264	biolink:NamedThing	deoxyribonucleotide catabolic process	The chemical reactions and pathways resulting in the breakdown of a deoxyribonucleotide, a compound consisting of deoxyribonucleoside (a base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.	tmpzr1t_l9r_go_relaxed.owl	deoxyribonucleotide degradation|deoxyribonucleotide catabolism|deoxyribonucleotide breakdown													biological_process											owl:Class	
GO:1990595	biolink:NamedThing	mast cell secretagogue receptor activity	Combining with basic secretagogues to initiate pseudo-allergic reactions in mast cells.	tmpzr1t_l9r_go_relaxed.owl								sp	2014-12-22T10:04:43Z					molecular_function											owl:Class	
GO:2001313	biolink:NamedThing	UDP-4-deoxy-4-formamido-beta-L-arabinopyranose metabolic process	The chemical reactions and pathways involving a UDP-4-deoxy-4-formamido-beta-L-arabinopyranose.	tmpzr1t_l9r_go_relaxed.owl	UDP-4-deoxy-4-formamido-beta-L-arabinopyranose metabolism							pr	2012-03-22T01:19:54Z					biological_process											owl:Class	
GO:0098761	biolink:NamedThing	cellular response to interleukin-7	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-7 stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to IL-7													biological_process											owl:Class	
GO:0098760	biolink:NamedThing	response to interleukin-7	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-7 stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to IL-7													biological_process											owl:Class	
GO:0043840	biolink:NamedThing	branched-chain amino acid:2-keto-4-methylthiobutyrate aminotransferase activity	Catalysis of the reaction: 2-keto-4-methylthiobutyrate + L-phenylalanine = phenylpyruvate + L-methionine.	tmpzr1t_l9r_go_relaxed.owl	branched chain amino acid:2-keto-4-methylthiobutyrate aminotransferase activity|branched-chain-amino-acid:2-keto-4-methylthiobutyrate aminotransferase activity|branched-chain amino acid aminotransferase|BCAT				MetaCyc:RXN-7708									molecular_function											owl:Class	
GO:2000058	biolink:NamedThing	regulation of ubiquitin-dependent protein catabolic process	Any process that modulates the frequency, rate or extent of ubiquitin-dependent protein catabolic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of protein ubiquitinylation during ubiquitin-dependent protein catabolic process|regulation of protein ubiquitination during ubiquitin-dependent protein catabolism|regulation of protein degradation tagging activity|regulation of protein ubiquitylation during ubiquitin-dependent protein catabolic process|regulation of myofibrillar protein ubiquitination during ubiquitin-dependent protein breakdown|regulation of protein ubiquitinylation during ubiquitin-dependent protein catabolism|regulation of myofibrillar protein ubiquitination during ubiquitin-dependent protein catabolism|regulation of protein ubiquitylation during ubiquitin-dependent protein catabolism|regulation of protein ubiquitination during ubiquitin-dependent protein breakdown|regulation of protein ubiquitination during ubiquitin-dependent protein degradation|regulation of protein ubiquitination during ubiquitin-dependent protein catabolic process|regulation of myofibrillar protein ubiquitination during ubiquitin-dependent protein catabolic process|regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process|regulation of myofibrillar protein ubiquitination during ubiquitin-dependent protein degradation							jl	2010-08-20T01:23:46Z					biological_process											owl:Class	
GO:0002466	biolink:NamedThing	peripheral tolerance induction to self antigen	Tolerance induction to self antigens in the peripheral lymphoid tissues: blood, lymph nodes, spleen, and mucosal-associated lymphoid tissues.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:2000172	biolink:NamedThing	regulation of branching morphogenesis of a nerve	Any process that modulates the frequency, rate or extent of branching morphogenesis of a nerve.	tmpzr1t_l9r_go_relaxed.owl								rl	2010-10-07T12:07:54Z					biological_process											owl:Class	
GO:0001704	biolink:NamedThing	formation of primary germ layer	The formation of the ectoderm, mesoderm and endoderm during gastrulation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0048587	biolink:NamedThing	regulation of short-day photoperiodism, flowering	Any process that modulates the frequency, rate or extent of short-day photoperiodism, where the response associated with the photoperiodism is flowering. Flowering is defined by the switch from the vegetative to the reproductive phase.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0039522	biolink:NamedThing	suppression by virus of host mRNA export from nucleus	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of movement of mRNA from the nucleus to the cytoplasm in the host organism.	tmpzr1t_l9r_go_relaxed.owl	suppression of host mRNA nuclear export by virus|inhibition by virus of host mRNA nuclear export|inhibition of host mRNA nuclear export by virus|negative regulation by virus of host mRNA nuclear export				VZ:902			bf	2011-06-22T04:34:14Z					biological_process											owl:Class	
GO:0002350	biolink:NamedThing	peripheral B cell positive selection	Any process leading to positive selection of B cells in the periphery. Positive selection is the process in which B or T cells are selected to survive based on signaling through their antigen receptors.	tmpzr1t_l9r_go_relaxed.owl	peripheral B lymphocyte positive selection|peripheral B-cell positive selection|peripheral B-lymphocyte positive selection													biological_process											owl:Class	
GO:0002231	biolink:NamedThing	detection of oomycetes	The series of events in which a stimulus from an oomycetes is received and converted into a molecular signal.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0045467	biolink:NamedThing	R7 cell development	The process whose specific outcome is the progression of the R7 photoreceptor over time, from its formation to the mature structure. The R7 photoreceptor is the last photoreceptor to develop in the ommatidium.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0003021	biolink:NamedThing	detection of increased carbon dioxide by chemoreceptor signaling	The process in which information about the levels of carbon dioxide are received and are converted to a molecular signal by chemoreceptors in the carotid bodies and the aortic bodies.	tmpzr1t_l9r_go_relaxed.owl	detection of increased carbon dioxide by chemoreceptor signalling													biological_process											owl:Class	
GO:0018185	biolink:NamedThing	poly-N-methyl-propylamination	The modification of peptidyl-lysine by the addition of an N6-propylamino and of propylmethylamino units, forming N6-(propylamino-poly(propylmethylamino)-propyldimethylamine)-L-lysine, typical of the silicate binding protein silaffin.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0278									biological_process											owl:Class	
GO:0071470	biolink:NamedThing	cellular response to osmotic stress	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell.	tmpzr1t_l9r_go_relaxed.owl	cellular osmotic response|cellular osmotic stress response							mah	2009-12-18T11:45:33Z					biological_process											owl:Class	
GO:0106088	biolink:NamedThing	regulation of cell adhesion involved in sprouting angiogenesis	Any process that modulates the frequency, rate or extent of cell adhesion involved in sprouting angiogenesis.	tmpzr1t_l9r_go_relaxed.owl								hjd	2018-01-22T18:24:12Z					biological_process											owl:Class	
GO:0039667	biolink:NamedThing	viral entry into host cell via pilus retraction	The uptake of a virus or viral genetic material into a host cell which occurs through retraction of a virion-bound pilus.	tmpzr1t_l9r_go_relaxed.owl						This method of entry into the cell differs between viruses; filamentous bacteriophages have rod-shaped virions which attach to the tip of the pilus; after retraction of the pilus with the virion attached, the genome can enter the host cell through the pilus basal pore. For icosahedral viruses, retraction of the pilus brings the virus in contact with the cell membrane and the genome can enter the cell via membrane fusion or genome injection. In GO, viral entry begins after viral attachment; for pilus-attachment proteins see instead: viral attachment to host cell pilus ; GO:0039666.		bf	2013-09-04T14:32:19Z					biological_process											owl:Class	
GO:0007159	biolink:NamedThing	leukocyte cell-cell adhesion	The attachment of a leukocyte to another cell via adhesion molecules.	tmpzr1t_l9r_go_relaxed.owl	leukocyte cell adhesion|leukocyte adhesion													biological_process											owl:Class	
GO:0052595	biolink:NamedThing	aliphatic-amine oxidase activity	Catalysis of the reaction: an aliphatic amine + H2O + O2 = an aldehyde + NH3 + hydrogen peroxide + H+.	tmpzr1t_l9r_go_relaxed.owl	aliphatic-amine:oxygen oxidoreductase(deaminating) activity				RHEA:16153|MetaCyc:AMINEOXID-RXN|EC:1.4.3.21									molecular_function											owl:Class	
GO:0050973	biolink:NamedThing	detection of mechanical stimulus involved in equilibrioception	The series of events involved in equilibrioception in which a mechanical stimulus is received and converted into a molecular signal. During equilibrioception, mechanical stimuli may be in the form of input from pressure receptors or from the labyrinth system of the inner ears.	tmpzr1t_l9r_go_relaxed.owl	sensory detection of mechanical stimulus during equilibrioception|sensory transduction of mechanical stimulus during equilibrioception|equilibrioception, detection of mechanical stimulus|equilibrioception, sensory detection of mechanical stimulus|equilibrioception, sensory transduction of mechanical stimulus													biological_process											owl:Class	
GO:0043952	biolink:NamedThing	protein transport by the Sec complex	The process in which unfolded proteins are transported across the cytoplasmic membrane in Gram-positive and Gram-negative bacteria by the Sec complex, in a process involving proteolytic cleavage of an N-terminal signal peptide.	tmpzr1t_l9r_go_relaxed.owl	protein translocation by the Sec complex|protein secretion by the Sec complex					Note that this term represents an activity and not a cellular structure. Consider also annotating to the cellular structure term 'cell envelope Sec protein transport complex ; GO:0031522'. For proteins involved in bacterial type II secretion across the outer membrane, consider annotating to 'protein secretion by the type II secretion system ; GO:0015628'. For proteins involved in Sec-complex dependent translocation into the eukaryotic endoplasmic reticulum, consider annotating to 'SRP-dependent cotranslational protein targeting to membrane, translocation ; GO:0006616'. Note that this term is used for annotation of proteins that compose the transport complex but not the proteins being transported.								biological_process											owl:Class	
GO:0018035	biolink:NamedThing	C-terminal peptidyl-arginine amidation	The formation of a C-terminal peptidyl-arginine amide by hydrolysis and oxidation of an interior Arg-Gly peptide in a secreted protein.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0082									biological_process											owl:Class	
GO:0018229	biolink:NamedThing	peptidyl-L-cysteine methyl ester biosynthetic process from peptidyl-cysteine	The modification of a C-terminal peptidyl-cysteine to form peptidyl-L-cysteine methyl ester.	tmpzr1t_l9r_go_relaxed.owl	peptidyl-L-cysteine methyl ester anabolism from peptidyl-cysteine|peptidyl-L-cysteine methyl ester synthesis from peptidyl-cysteine|peptidyl-L-cysteine methyl ester formation from peptidyl-cysteine				RESID:AA0105									biological_process											owl:Class	
GO:1902721	biolink:NamedThing	negative regulation of prolactin secretion	Any process that stops, prevents or reduces the frequency, rate or extent of prolactin secretion.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of prolactin secretion|downregulation of prolactin secretion|inhibition of prolactin secretion|down regulation of prolactin secretion							mr	2014-02-24T16:09:28Z					biological_process											owl:Class	
GO:0019321	biolink:NamedThing	pentose metabolic process	The chemical reactions and pathways involving a pentose, any monosaccharide with a chain of five carbon atoms in the molecule.	tmpzr1t_l9r_go_relaxed.owl	pentose metabolism													biological_process											owl:Class	
GO:0106322	biolink:NamedThing	S-(hydroxymethyl)glutathione dehydrogenase NAD activity	Catalysis of the reaction: S-(hydroxymethyl)glutathione + NAD+ = S-formylglutathione + NADH + H+.	tmpzr1t_l9r_go_relaxed.owl					EC:1.1.1.284|RHEA:19985			hjd	2020-09-23T15:26:40Z					molecular_function											owl:Class	
GO:1902840	biolink:NamedThing	positive regulation of nuclear migration along microtubule	Any process that activates or increases the frequency, rate or extent of nuclear migration along microtubule.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of microtubule-dependent nucleus positioning|positive regulation of transport of nucleus by microtubules|activation of microtubule-dependent nuclear positioning|positive regulation of microtubule cytoskeleton-dependent nucleus positioning|positive regulation of nuclear migration, microtubule-mediated|activation of microtubule-dependent nucleus positioning|positive regulation of microtubule cytoskeleton-dependent nuclear positioning|up-regulation of microtubule-dependent nuclear positioning|activation of microtubule cytoskeleton-dependent nuclear positioning|up regulation of transport of nucleus by microtubules|activation of transport of nucleus, microtubule-mediated|activation of nuclear migration along microtubule|up-regulation of microtubule-dependent nucleus positioning|up regulation of microtubule cytoskeleton-dependent nucleus positioning|up regulation of nuclear migration along microtubule|activation of transport of nucleus by microtubules|upregulation of microtubule-dependent nuclear positioning|up-regulation of transport of nucleus by microtubules|up-regulation of microtubule-mediated nuclear migration|up-regulation of microtubule cytoskeleton-dependent nucleus positioning|upregulation of microtubule-dependent nucleus positioning|activation of microtubule cytoskeleton-dependent nucleus positioning|up-regulation of nuclear migration along microtubule|up regulation of nuclear migration, microtubule-mediated|up-regulation of nuclear migration, microtubule-mediated|upregulation of microtubule cytoskeleton-dependent nuclear positioning|up regulation of microtubule-mediated nuclear migration|positive regulation of transport of nucleus, microtubule-mediated|upregulation of microtubule-mediated nuclear migration|up regulation of transport of nucleus, microtubule-mediated|upregulation of transport of nucleus, microtubule-mediated|up regulation of microtubule-dependent nuclear positioning|upregulation of microtubule cytoskeleton-dependent nucleus positioning|activation of microtubule-mediated nuclear migration|positive regulation of microtubule-dependent nuclear positioning|up-regulation of microtubule cytoskeleton-dependent nuclear positioning|upregulation of nuclear migration, microtubule-mediated|positive regulation of microtubule-mediated nuclear migration|activation of nuclear migration, microtubule-mediated|up regulation of microtubule cytoskeleton-dependent nuclear positioning|up regulation of microtubule-dependent nucleus positioning|up-regulation of transport of nucleus, microtubule-mediated|upregulation of transport of nucleus by microtubules|upregulation of nuclear migration along microtubule							vw	2014-04-01T13:50:35Z					biological_process											owl:Class	
GO:0090504	biolink:NamedThing	epiboly	The expansion of one cell sheet over other cells or yolk.	tmpzr1t_l9r_go_relaxed.owl								tb	2012-10-22T12:29:52Z					biological_process											owl:Class	
GO:0043748	biolink:NamedThing	O-succinylbenzoate synthase activity	Catalysis of the reaction: 2-succinylbenzoate + H2O = 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate.	tmpzr1t_l9r_go_relaxed.owl					EC:4.2.1.113									molecular_function											owl:Class	
GO:0034699	biolink:NamedThing	response to luteinizing hormone	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a luteinizing hormone stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to luteinizing hormone stimulus													biological_process											owl:Class	
GO:0015745	biolink:NamedThing	tartrate transmembrane transport	The process in which tartrate is transported across a lipid bilayer, from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	tartrate transport													biological_process											owl:Class	
GO:1905943	biolink:NamedThing	negative regulation of formation of growth cone in injured axon	Any process that stops, prevents or reduces the frequency, rate or extent of formation of growth cone in injured axon.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of formation of growth cone in injured axon|inhibition of formation of growth cone in injured axon|downregulation of formation of growth cone in injured axon|down regulation of formation of growth cone in injured axon							rz	2017-02-13T09:09:13Z					biological_process											owl:Class	
GO:0010952	biolink:NamedThing	positive regulation of peptidase activity	Any process that increases the frequency, rate or extent of peptidase activity, the hydrolysis of peptide bonds within proteins.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-04-27T11:54:32Z					biological_process											owl:Class	
GO:1903086	biolink:NamedThing	negative regulation of sinapate ester biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of sinapate ester biosynthesis.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of sinapate ester biosynthetic process|inhibition of sinapate ester formation|inhibition of sinapate ester biosynthesis|inhibition of sinapate ester synthesis|downregulation of sinapate ester formation|negative regulation of sinapate ester formation|inhibition of sinapate ester biosynthetic process|down-regulation of sinapate ester biosynthesis|down regulation of sinapate ester anabolism|negative regulation of sinapate ester anabolism|negative regulation of sinapate ester synthesis|downregulation of sinapate ester synthesis|downregulation of sinapate ester biosynthetic process|downregulation of sinapate ester anabolism|down-regulation of sinapate ester anabolism|down regulation of sinapate ester biosynthesis|down-regulation of sinapate ester synthesis|inhibition of sinapate ester anabolism|negative regulation of sinapate ester biosynthesis|down regulation of sinapate ester formation|down regulation of sinapate ester synthesis|down-regulation of sinapate ester formation|down regulation of sinapate ester biosynthetic process|downregulation of sinapate ester biosynthesis							tb	2014-05-30T22:00:18Z					biological_process											owl:Class	
GO:0140580	biolink:NamedThing	mitochondrion autophagosome adaptor activity	The binding activity of a molecule that brings together a mitochondrial membrane and an autophagosome during mitophagy.	tmpzr1t_l9r_go_relaxed.owl	mitophagy receptor	https://github.com/geneontology/go-ontology/issues/20668						pg	2021-01-18T11:03:49Z					molecular_function											owl:Class	
GO:0042059	biolink:NamedThing	negative regulation of epidermal growth factor receptor signaling pathway	Any process that stops, prevents, or reduces the frequency, rate or extent of epidermal growth factor receptor signaling pathway activity.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of EGF receptor signaling pathway|negative regulation of EGF receptor signalling pathway|inhibition of epidermal growth factor receptor signaling pathway|down-regulation of epidermal growth factor receptor signaling pathway|down regulation of epidermal growth factor receptor signaling pathway|downregulation of epidermal growth factor receptor signaling pathway|negative regulation of EGFR signaling pathway													biological_process											owl:Class	
GO:0042058	biolink:NamedThing	regulation of epidermal growth factor receptor signaling pathway	Any process that modulates the frequency, rate or extent of epidermal growth factor receptor signaling pathway activity.	tmpzr1t_l9r_go_relaxed.owl	regulation of EGF receptor signaling pathway|regulation of EGF receptor signalling pathway|regulation of EGFR signaling pathway													biological_process											owl:Class	
GO:0140479	biolink:NamedThing	ergothioneine biosynthesis from histidine via hercynylcysteine sulfoxide synthase	A biosynthetic process that results in the formation of ergothioneine from histidine via a set of steps including the hercynylcysteine sulfoxide synthase reaction, which converts N-alpha,N-alpha,N-alpha-trimethyl-L-histidine directly to hercynylcysteine sulfoxide.	tmpzr1t_l9r_go_relaxed.owl								pg	2020-06-25T09:58:21Z					biological_process											owl:Class	
GO:0047227	biolink:NamedThing	indolylacetyl-myo-inositol galactosyltransferase activity	Catalysis of the reaction: 1L-1-O-(indol-3-yl)acetyl-myo-inositol + UDP-D-galactose = 5-O-(indol-3-ylacetyl)-myo-inositol D-galactoside + H(+) + UDP.	tmpzr1t_l9r_go_relaxed.owl	UDP-galactose:(indol-3-yl)acetyl-myo-inositol 5-O-D-galactosyltransferase activity|uridine diphosphogalactose-indolylacetylinositol galactosyltransferase activity|indol-3-ylacetyl-myo-inositol galactoside synthase activity|UDP-galactose:indol-3-ylacetyl-myo-inositol 5-O-D-galactosyltransferase activity				MetaCyc:2.4.1.156-RXN|KEGG_REACTION:R04334|RHEA:21148|EC:2.4.1.156									molecular_function											owl:Class	
GO:2000238	biolink:NamedThing	regulation of tRNA export from nucleus	Any process that modulates the frequency, rate or extent of tRNA export from nucleus.	tmpzr1t_l9r_go_relaxed.owl	regulation of tRNA transport from nucleus to cytoplasm|regulation of tRNA-nucleus export|regulation of tRNA export from cell nucleus|regulation of tRNA export out of nucleus							mah	2010-11-10T12:39:33Z					biological_process											owl:Class	
GO:0031408	biolink:NamedThing	oxylipin biosynthetic process	The chemical reactions and pathways resulting in the formation of any oxylipin, any of a group of biologically active compounds formed by oxidative metabolism of polyunsaturated fatty acids.	tmpzr1t_l9r_go_relaxed.owl	oxylipin synthesis|oxylipin biosynthesis|oxylipin formation|oxylipin anabolism													biological_process											owl:Class	
GO:0047366	biolink:NamedThing	quercetin-3-sulfate 4'-sulfotransferase activity	Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + quercetin 3-sulfate = adenosine 3',5'-diphosphate + H(+) + quercetin 3,4'-disulfate.	tmpzr1t_l9r_go_relaxed.owl	quercetin-3-sulphate 4'-sulphotransferase activity|flavonol 4'-sulfotransferase activity|3'-phosphoadenylyl-sulfate:quercetin-3-sulfate 4'-sulfotransferase activity|PAPS:flavonol 3-sulfate 4'-sulfotransferase activity				MetaCyc:2.8.2.27-RXN|KEGG_REACTION:R02633|RHEA:17205|EC:2.8.2.27									molecular_function											owl:Class	
GO:1900297	biolink:NamedThing	regulation of hexasaccharide transport	Any process that modulates the frequency, rate or extent of hexasaccharide transport.	tmpzr1t_l9r_go_relaxed.owl								tt	2012-04-05T07:44:31Z					biological_process											owl:Class	
GO:0090260	biolink:NamedThing	negative regulation of retinal ganglion cell axon guidance	Any process that decreases the frequency, rate, or extent of retinal ganglion cell axon guidance, the process in which the migration of an axon growth cone of a retinal ganglion cell (RGC) is directed to its target in the brain in response to a combination of attractive and repulsive cues.	tmpzr1t_l9r_go_relaxed.owl	axon growth cone collapse					Note that growth cone collapse has been observed only in assays performed in vitro.		tb	2010-02-03T04:13:59Z					biological_process											owl:Class	
GO:1903968	biolink:NamedThing	cellular response to micafungin	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a micafungin stimulus.	tmpzr1t_l9r_go_relaxed.owl								al	2015-02-27T09:57:44Z					biological_process											owl:Class	
GO:1904573	biolink:NamedThing	regulation of selenocysteine insertion sequence binding	Any process that modulates the frequency, rate or extent of selenocysteine insertion sequence binding.	tmpzr1t_l9r_go_relaxed.owl	regulation of SECIS binding							sl	2015-08-19T17:51:09Z					biological_process											owl:Class	
GO:0003357	biolink:NamedThing	noradrenergic neuron differentiation	The process in which a relatively unspecialized cell acquires specialized features of an noradrenergic neuron, a neuron that secretes noradrenaline.	tmpzr1t_l9r_go_relaxed.owl	norepinephrine secreting neuron differentiation							dph	2009-12-03T10:34:30Z					biological_process											owl:Class	
GO:0019303	biolink:NamedThing	D-ribose catabolic process	The chemical reactions and pathways resulting in the breakdown of D-ribose (ribo-pentose).	tmpzr1t_l9r_go_relaxed.owl	D-ribose degradation|D-ribose catabolism|D-ribose breakdown				MetaCyc:RIBOKIN-PWY									biological_process											owl:Class	
GO:0006014	biolink:NamedThing	D-ribose metabolic process	The chemical reactions and pathways involving D-ribose (ribo-pentose). As beta-D-ribofuranose, D-ribose forms the glycose group of all ribonucleosides, ribonucleotides and ribonucleic acids, and also of ribose phosphates, various glycosides, some coenzymes and some forms of vitamin B12.	tmpzr1t_l9r_go_relaxed.owl	D-ribose metabolism													biological_process											owl:Class	
GO:0140636	biolink:NamedThing	copper import into the mitochondrion	The process in which copper is transported from the cytosol into the mitochondrial matrix.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/21294						pg	2021-04-14T09:59:21Z					biological_process											owl:Class	
GO:1905355	biolink:NamedThing	spine apparatus assembly	The aggregation, arrangement and bonding together of a set of components to form a spine apparatus.	tmpzr1t_l9r_go_relaxed.owl	dense material formation|spine apparatus formation|dense material assembly							bf	2016-08-09T10:12:29Z					biological_process											owl:Class	
GO:1902850	biolink:NamedThing	microtubule cytoskeleton organization involved in mitosis	Any microtubule cytoskeleton organization that is involved in mitosis.	tmpzr1t_l9r_go_relaxed.owl	microtubule cytoskeleton organisation involved in mitosis|microtubule cytoskeleton organization and biogenesis involved in mitosis|microtubule dynamics involved in mitosis							vw	2014-04-02T14:19:38Z					biological_process											owl:Class	
GO:0140710	biolink:NamedThing	regulation of Frizzled Nuclear Import pathway	Any process that modulates the frequency, rate or extent of a Frizzled Nuclear Import pathway.	tmpzr1t_l9r_go_relaxed.owl	regulation of Frizzled Nuclear Import Wnt Pathway|regulation of FNI	https://github.com/geneontology/go-ontology/issues/21483						pg	2021-09-08T09:14:01Z					biological_process											owl:Class	
GO:2001083	biolink:NamedThing	alpha-D-glucan binding	Binding to alpha-D-glucan.	tmpzr1t_l9r_go_relaxed.owl								jl	2011-09-15T01:26:14Z					molecular_function											owl:Class	
GO:1901259	biolink:NamedThing	chloroplast rRNA processing	Any rRNA processing that takes place in chloroplast.	tmpzr1t_l9r_go_relaxed.owl								tb	2012-08-10T17:43:19Z					biological_process											owl:Class	
GO:0000806	biolink:NamedThing	Y chromosome	The sex chromosome present in males of species in which the male is the heterogametic sex; generally, the sex chromosome that pairs with the X chromosome in the heterogametic sex. The Y chromosome is absent from the cells of females and present in one copy in the somatic cells of males.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Y_chromosome									cellular_component											owl:Class	
GO:0021635	biolink:NamedThing	trigeminal nerve maturation	A developmental process, independent of morphogenetic (shape) change, that is required for the trigeminal nerve to attain its fully functional state. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains sensory branches that reach the pterygopalatine fossa via the inferior orbital fissure (face, cheek and upper teeth) and pterygopalatine canal (soft and hard palate, nasal cavity and pharynx). The motor part of the mandibular branch is distributed to the muscles of mastication, the mylohyoid muscle and the anterior belly of the digastric. The mandibular nerve also innervates the tensor veli palatini and tensor tympani muscles. The sensory part of the mandibular nerve is composed of branches that carry general sensory information from the mucous membranes of the mouth and cheek, anterior two-thirds of the tongue, lower teeth, skin of the lower jaw, side of the head and scalp and meninges of the anterior and middle cranial fossae.	tmpzr1t_l9r_go_relaxed.owl	CN V maturation													biological_process											owl:Class	
GO:0033001	biolink:NamedThing	Fc-gamma receptor III complex	A protein complex composed of an Fc-gamma RIII alpha chain and an Fc-epsilon RI gamma chain dimer with or without an Fc-epsilon RI beta chain and additional signaling components. The complex functions primarily as an activating receptor for IgG.	tmpzr1t_l9r_go_relaxed.owl	FcgRIII complex|IgG receptor complex|immunoglobulin G receptor complex													cellular_component											owl:Class	
GO:0032997	biolink:NamedThing	Fc receptor complex	A protein complex composed of a subunit or subunits capable of binding the Fc portion of an immunoglobulin with additional signaling components. The complex functions as a receptor for immunoglobulin.	tmpzr1t_l9r_go_relaxed.owl	FcR complex|immunoglobulin receptor complex|Fc-receptor complex													cellular_component											owl:Class	
GO:0060495	biolink:NamedThing	cell-cell signaling involved in lung development	Any process that mediates the transfer of information from one cell to another and contributes to the progression of the lung, from its initial state to the mature structure.	tmpzr1t_l9r_go_relaxed.owl	cell-cell signalling involved in lung development													biological_process											owl:Class	
GO:1904910	biolink:NamedThing	regulation of establishment of RNA localization to telomere	Any process that modulates the frequency, rate or extent of establishment of RNA localization to telomere.	tmpzr1t_l9r_go_relaxed.owl	regulation of establishment of RNA localisation to telomere							rph	2016-01-19T10:34:21Z					biological_process											owl:Class	
GO:2000192	biolink:NamedThing	negative regulation of fatty acid transport	Any process that stops, prevents, or reduces the frequency, rate or extent of fatty acid transport.	tmpzr1t_l9r_go_relaxed.owl								rl	2010-10-18T10:37:15Z					biological_process											owl:Class	
GO:0071390	biolink:NamedThing	cellular response to ecdysone	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ecdysone stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-12-11T04:03:57Z					biological_process											owl:Class	
GO:0003366	biolink:NamedThing	cell-matrix adhesion involved in ameboidal cell migration	The binding of a cell to the extracellular matrix that contributes to the directed movement of an ameboid cell.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-12-08T04:54:33Z					biological_process											owl:Class	
GO:0035255	biolink:NamedThing	ionotropic glutamate receptor binding	Binding to an ionotropic glutamate receptor. Ionotropic glutamate receptors bind glutamate and exert an effect through the regulation of ion channels.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0044193	biolink:NamedThing	host cell mitochondrial outer membrane	The outer, i.e. cytoplasm-facing, lipid bilayer of the host cell mitochondrial envelope.	tmpzr1t_l9r_go_relaxed.owl								jl	2009-10-15T04:18:44Z					cellular_component											owl:Class	
GO:0021955	biolink:NamedThing	central nervous system neuron axonogenesis	Generation of a long process from a neuron whose cell body resides in the central nervous system. The process carries efferent (outgoing) action potentials from the cell body towards target cells.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0050163	biolink:NamedThing	oxaloacetate tautomerase activity	Catalysis of the reaction: oxaloacetate = <stereo>enol</stereo>-oxaloacetate.	tmpzr1t_l9r_go_relaxed.owl	oxaloacetate keto-enol tautomerase activity|oxaloacetate keto-enol-isomerase activity|oxalacetic keto-enol isomerase activity				KEGG_REACTION:R00363|EC:5.3.2.2|RHEA:16021|MetaCyc:OXALOACETATE-TAUTOMERASE-RXN									molecular_function											owl:Class	
GO:0016862	biolink:NamedThing	intramolecular oxidoreductase activity, interconverting keto- and enol-groups	Catalysis of an oxidation-reduction (redox) reaction in which the hydrogen donor and acceptor, which is a keto- or an enol-group, are the same molecule, and no oxidized product appears.	tmpzr1t_l9r_go_relaxed.owl	intramolecular isomerase activity, interconverting keto- and enol-groups				EC:5.3.2.-									molecular_function											owl:Class	
GO:0003257	biolink:NamedThing	positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation	Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the differentiation of a myocardial precursor cell.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-10-15T01:07:25Z					biological_process											owl:Class	
GO:1902042	biolink:NamedThing	negative regulation of extrinsic apoptotic signaling pathway via death domain receptors	Any process that stops, prevents or reduces the frequency, rate or extent of extrinsic apoptotic signaling pathway via death domain receptors.	tmpzr1t_l9r_go_relaxed.owl	downregulation of death receptor-mediated apoptosis|down regulation of extrinsic apoptotic signaling pathway via death domain receptors|inhibition of extrinsic apoptotic signaling pathway via death domain receptors|down regulation of death receptor-mediated apoptosis|inhibition of death receptor-mediated apoptosis|down-regulation of death receptor-mediated apoptosis|downregulation of extrinsic apoptotic signaling pathway via death domain receptors|negative regulation of death receptor-mediated apoptosis|down-regulation of extrinsic apoptotic signaling pathway via death domain receptors							lb	2013-04-03T07:17:04Z					biological_process											owl:Class	
GO:2000914	biolink:NamedThing	positive regulation of galactoglucomannan catabolic process	Any process that activates or increases the frequency, rate or extent of galactoglucomannan catabolic process.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of galactoglucomannan catabolism							tt	2011-07-29T07:51:50Z					biological_process											owl:Class	
GO:0103011	biolink:NamedThing	mannosylfructose-phosphate synthase activity	Catalysis of the reaction: GDP-alpha-D-mannose + beta-D-fructofuranose 6-phosphate <=> mannosylfructose-phosphate + GDP.	tmpzr1t_l9r_go_relaxed.owl					EC:2.4.1.246|MetaCyc:RXN-9935|RHEA:26039									molecular_function											owl:Class	
GO:0098971	biolink:NamedThing	anterograde dendritic transport of neurotransmitter receptor complex	The directed movement of a neurotransmitter receptor complex along microtubules in nerve cell dendrites towards the postsynapse.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0018134	biolink:NamedThing	peptide cross-linking via glycine oxazolecarboxylic acid	The chemical reactions and pathways resulting in the formation of a peptidyl serine-peptidyl glycine cross-link by the condensation of a serine hydroxyl with the carbonyl of the preceding residue and alpha-beta dehydrogenation.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0240									biological_process											owl:Class	
GO:0050731	biolink:NamedThing	positive regulation of peptidyl-tyrosine phosphorylation	Any process that activates or increases the frequency, rate or extent of the phosphorylation of peptidyl-tyrosine.	tmpzr1t_l9r_go_relaxed.owl	upregulation of peptidyl-tyrosine phosphorylation|activation of peptidyl-tyrosine phosphorylation|stimulation of peptidyl-tyrosine phosphorylation|up regulation of peptidyl-tyrosine phosphorylation|up-regulation of peptidyl-tyrosine phosphorylation													biological_process											owl:Class	
GO:0090015	biolink:NamedThing	positive regulation of leaflet formation by auxin mediated signaling pathway	Any process that increases the frequency, rate or extent of leaflet formation as a result of the series of molecular signals generated in response to detection of auxin.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of leaflet formation by auxin mediated signalling pathway							tb	2009-07-29T11:18:45Z					biological_process											owl:Class	
GO:0009734	biolink:NamedThing	auxin-activated signaling pathway	A series of molecular signals generated by the binding of the plant hormone auxin to a receptor, and ending with modulation of a downstream cellular process, e.g. transcription.	tmpzr1t_l9r_go_relaxed.owl	auxin signal transduction|auxin signaling|auxin mediated signaling pathway|auxin-regulated transcription|auxin mediated signalling													biological_process											owl:Class	
GO:0032117	biolink:NamedThing	horsetail-astral microtubule array	An array of astral microtubules that emanates from the spindle pole body during meiosis and facilitates horsetail nuclear movement.	tmpzr1t_l9r_go_relaxed.owl	HAA													cellular_component											owl:Class	
GO:1902085	biolink:NamedThing	fumagillin catabolic process	The chemical reactions and pathways resulting in the breakdown of fumagillin.	tmpzr1t_l9r_go_relaxed.owl	fumagillin breakdown|fumagillin degradation|fumagillin catabolism							di	2013-04-25T14:00:45Z					biological_process											owl:Class	
GO:0010957	biolink:NamedThing	negative regulation of vitamin D biosynthetic process	Any process that decreases the rate, frequency or extent of a vitamin D biosynthetic process. Vitamin D biosynthesis is the chemical reactions and pathways resulting in the formation of vitamin D, any of a group of related, fat-soluble compounds that are derived from delta-5,7 steroids and play a central role in calcium metabolism. Specific forms of vitamin D include calciferol (ergocalciferol; vitamin D2) and cholecalciferol (calciol; vitamin D3).	tmpzr1t_l9r_go_relaxed.owl								tb	2009-05-06T11:25:12Z					biological_process											owl:Class	
GO:0044583	biolink:NamedThing	cellotriose binding	Binding to cellotriose.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-04-24T04:48:01Z					molecular_function											owl:Class	
GO:0048031	biolink:NamedThing	trisaccharide binding	Binding to a trisaccharide. Trisaccharides are sugars composed of three monosaccharide units.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1903765	biolink:NamedThing	negative regulation of potassium ion export across plasma membrane	Any process that stops, prevents or reduces the frequency, rate or extent of potassium ion export across the plasma membrane.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of potassium ion export across plasma membrane|downregulation of potassium ion export across plasma membrane|inhibition of potassium ion export across plasma membrane|down regulation of potassium ion export across plasma membrane|inhibition of potassium ion export|negative regulation of potassium ion export|down-regulation of potassium ion export|inhibition of potassium export|downregulation of potassium export|down-regulation of potassium export|downregulation of potassium ion export|negative regulation of potassium export|down regulation of potassium export|down regulation of potassium ion export							rl	2013-07-17T16:40:02Z			GO:1902303		biological_process											owl:Class	
GO:1901380	biolink:NamedThing	negative regulation of potassium ion transmembrane transport	Any process that stops, prevents or reduces the frequency, rate or extent of potassium ion transmembrane transport.	tmpzr1t_l9r_go_relaxed.owl	down regulation of potassium ion transmembrane transport|negative regulation of potassium ion membrane transport|inhibition of potassium ion transmembrane transport|down-regulation of potassium ion transmembrane transport|downregulation of potassium ion transmembrane transport							rl	2012-09-28T15:59:08Z					biological_process											owl:Class	
GO:0046218	biolink:NamedThing	indolalkylamine catabolic process	The chemical reactions and pathways resulting in the breakdown of indolalkylamines, indole or indole derivatives containing a primary, secondary, or tertiary amine group.	tmpzr1t_l9r_go_relaxed.owl	indolalkylamine breakdown|indolalkylamine catabolism|indolalkylamine degradation													biological_process											owl:Class	
GO:0006586	biolink:NamedThing	indolalkylamine metabolic process	The chemical reactions and pathways involving indolalkylamines, indole or indole derivatives containing a primary, secondary, or tertiary amine group.	tmpzr1t_l9r_go_relaxed.owl	indolamine metabolic process|indolamine metabolism|indolalkylamine metabolism													biological_process											owl:Class	
GO:0102185	biolink:NamedThing	4alpha-hydroxymethyl,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-cholest-24-en-3beta-ol-4alpha-methyl oxidase activity	Catalysis of the reaction: 4alpha-hydroxymethyl,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-cholest-24-en-3beta-ol + NADH(2-) + O2 + H+ <=> 4alpha-formyl,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-cholest-24-en-3beta-ol + NAD(1-) + 2 H2O.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-11947									molecular_function											owl:Class	
GO:0140403	biolink:NamedThing	effector-mediated suppression of host innate immune response	A process mediated by a molecule secreted by a symbiont that results in the suppression of a host innate immune response. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	effector-triggered suppression of host immune innate response by symbiont|effector triggered suppression of host immune innate response by symbiont|effector-mediated suppression of host immune innate response by symbiont|effector-mediated suppression of host innate immunity|effector dependent suppression of host immune innate response by symbiont|effector-mediated suppression of host innate immune response by symbiont|effector-dependent suppression of host immune innate response by symbiont							pg	2019-12-05T11:34:55Z					biological_process											owl:Class	
GO:0043632	biolink:NamedThing	modification-dependent macromolecule catabolic process	The chemical reactions and pathways resulting in the breakdown of a macromolecule, initiated by covalent modification of the target molecule.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0060176	biolink:NamedThing	regulation of aggregation involved in sorocarp development	Any process that modulates the frequency, rate or extent of aggregation during sorocarp development. Aggregation involved in sorocarp development is the process whose specific outcome is the progression of the aggregate over time, from its formation to the point when a slug is formed. Aggregate development begins in response to starvation and continues by the chemoattractant-mediated movement of cells toward each other. The aggregate is a multicellular structure that gives rise to the slug.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0005384	biolink:NamedThing	manganese ion transmembrane transporter activity	Enables the transfer of manganese (Mn) ions from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl					RHEA:28699|Reactome:R-HSA-8959798									molecular_function											owl:Class	
GO:0043201	biolink:NamedThing	response to leucine	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leucine stimulus.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1903112	biolink:NamedThing	positive regulation of single-strand break repair via homologous recombination	Any process that activates or increases the frequency, rate or extent of single-strand break repair via homologous recombination.	tmpzr1t_l9r_go_relaxed.owl	upregulation of single-strand break repair via homologous recombination|up regulation of single-strand break repair via homologous recombination|activation of single-strand break repair via homologous recombination|up-regulation of single-strand break repair via homologous recombination							pr	2014-06-09T12:11:38Z					biological_process											owl:Class	
GO:1903518	biolink:NamedThing	positive regulation of single strand break repair	Any process that activates or increases the frequency, rate or extent of single strand break repair.	tmpzr1t_l9r_go_relaxed.owl	up regulation of single strand break repair|up-regulation of single strand break repair|upregulation of single strand break repair|activation of single strand break repair							rl	2014-10-06T10:59:10Z					biological_process											owl:Class	
GO:0140670	biolink:NamedThing	ATP-dependent cohesin unloading activity	Facilitating a conformational change to unload a cohesin complex from sister chromatids, driven by ATP hydrolysis.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/21700						pg	2021-06-24T13:36:05Z					molecular_function											owl:Class	
GO:0140083	biolink:NamedThing	ATP-dependent protein-DNA unloading activity	Facilitating the removal of a protein or protein complex from a DNA molecule driven by ATP hydrolysis. This can be achieved for example by introducing non-canonical DNA structures or generating torque to directly inhibit a protein-DNA binding interaction.	tmpzr1t_l9r_go_relaxed.owl	protein-DNA unloading ATPase activity	https://github.com/geneontology/go-ontology/issues/13992|https://github.com/geneontology/go-ontology/issues/21612						pg	2017-08-08T14:50:27Z					molecular_function											owl:Class	
GO:0102599	biolink:NamedThing	cytochrome P450 dependent beta-amyrin 12,13beta-epoxidase activity	Catalysis of the reaction: beta-amyrin + O2 + H+ + NAD(P)H <=> 12,13beta-epoxy-beta-amyrin + H2O + NAD(P).	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-15383									molecular_function											owl:Class	
GO:0042792	biolink:NamedThing	mitochondrial rRNA transcription	The synthesis of ribosomal RNA (rRNA) from a mitochondrial DNA template.	tmpzr1t_l9r_go_relaxed.owl	rRNA transcription from mitochondrial promoter													biological_process											owl:Class	
GO:0046708	biolink:NamedThing	IDP biosynthetic process	The chemical reactions and pathways resulting in the formation of IDP, inosine 5'-diphosphate.	tmpzr1t_l9r_go_relaxed.owl	IDP anabolism|IDP biosynthesis|IDP synthesis|IDP formation													biological_process											owl:Class	
GO:0002920	biolink:NamedThing	regulation of humoral immune response	Any process that modulates the frequency, rate, or extent of a humoral immune response.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:2000331	biolink:NamedThing	regulation of terminal button organization	Any process that modulates the frequency, rate or extent of terminal button organization.	tmpzr1t_l9r_go_relaxed.owl	regulation of terminal bouton organization|regulation of terminal button organisation|regulation of presynaptic bouton organization|regulation of synaptic bouton organization|regulation of bouton organization							mah	2011-01-28T11:29:08Z					biological_process											owl:Class	
GO:0044200	biolink:NamedThing	host cell nuclear membrane	Either of the lipid bilayers that surround the host nucleus and form the nuclear envelope; excludes the intermembrane space.	tmpzr1t_l9r_go_relaxed.owl								jl	2009-10-21T10:59:08Z					cellular_component											owl:Class	
GO:0047553	biolink:NamedThing	2-oxoglutarate synthase activity	Catalysis of the reaction: 2-oxoglutarate + CoA + oxidized ferredoxin = succinyl-CoA + CO2 + reduced ferredoxin.	tmpzr1t_l9r_go_relaxed.owl	2-oxoglutarate:ferredoxin oxidoreductase activity|alpha-ketoglutarate synthase activity|2-oxoglutarate:ferredoxin 2-oxidoreductase (decarboxylating)|2-oxoglutarate ferredoxin oxidoreductase activity|KGOR activity|2-oxoglutarate:ferredoxin 2-oxidoreductase (CoA-succinylating)|2-ketoglutarate ferredoxin oxidoreductase activity|alpha-ketoglutarate-ferredoxin oxidoreductase activity				RHEA:17297|MetaCyc:2-OXOGLUTARATE-SYNTHASE-RXN|EC:1.2.7.3									molecular_function											owl:Class	
GO:0072534	biolink:NamedThing	perineuronal net	A dense extracellular matrix (ECM) that forms around many neuronal cell bodies and dendrites late in development and is responsible for synaptic stabilization in the adult brain.	tmpzr1t_l9r_go_relaxed.owl	PNN							mah	2011-01-14T01:37:40Z					cellular_component											owl:Class	
GO:0098966	biolink:NamedThing	perisynaptic extracellular matrix	The portion of the extracellular matrix that lies within the perisynaptic space.	tmpzr1t_l9r_go_relaxed.owl	perisynaptic ECM|extrasynaptic extracellular matrix													cellular_component											owl:Class	
GO:0035268	biolink:NamedThing	protein mannosylation	The addition of a mannose residue to a protein acceptor molecule.	tmpzr1t_l9r_go_relaxed.owl	protein amino acid mannosylation													biological_process											owl:Class	
GO:0017018	biolink:NamedThing	myosin phosphatase activity	Catalysis of the reaction: phosphomyosin + H2O = myosin + phosphate.	tmpzr1t_l9r_go_relaxed.owl	myosin phosphatase myosin binding|myosin phosphatase, intrinsic catalyst activity				Reactome:R-HSA-445699|Reactome:R-HSA-390593							GO:0017019		molecular_function											owl:Class	
GO:0038183	biolink:NamedThing	bile acid signaling pathway	A series of molecular signals initiated by the binding of a bile acid to a receptor, and ending with regulation of a downstream cellular process, e.g. transcription.	tmpzr1t_l9r_go_relaxed.owl								bf	2013-05-16T10:35:10Z					biological_process											owl:Class	
GO:0044318	biolink:NamedThing	L-aspartate:fumarate oxidoreductase activity	Catalysis of the reaction: L-aspartate + fumarate = alpha-iminosuccinate + succinate.	tmpzr1t_l9r_go_relaxed.owl					EC:1.4.3.16	This is based on the finding that L-aspartate oxidase (NadB) of E. coli preferentially uses fumarate as the electron acceptor and does so under anaerobic conditions. The same enzyme uses oxygen as the electron acceptor under aerobic conditions. The EC conflates the two reactions in EC:1.4.3.16 (as they are catalyzed by the same enzyme).		jl	2010-07-14T01:50:01Z					molecular_function											owl:Class	
GO:0060620	biolink:NamedThing	regulation of cholesterol import	Any process that modulates the rate, frequency or extent of cholesterol import. Cholesterol import is the directed movement of cholesterol into a cell or organelle.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-05-18T01:41:08Z					biological_process											owl:Class	
GO:0016479	biolink:NamedThing	negative regulation of transcription by RNA polymerase I	Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase I.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of transcription from RNA polymerase I promoter|negative regulation of transcription from Pol I promoter|downregulation of transcription from RNA polymerase I promoter|down-regulation of transcription from RNA polymerase I promoter|down regulation of transcription from RNA polymerase I promoter|inhibition of transcription from RNA polymerase I promoter													biological_process											owl:Class	
GO:0034977	biolink:NamedThing	ABIN2-NFKB1-MAP3K8 complex	A protein complex that contains the precursor form of NF-kappaB (p105), the NF-kappaB inhibitor ABIN-2, and the kinase TPL-2 (MAP3K8); the complex stabilizes TPL-2 and is involved in signaling in lipopolysaccharide (LPS)-stimulated macrophages.	tmpzr1t_l9r_go_relaxed.owl	ABIN2-NFKB1-TPL-1 complex													cellular_component											owl:Class	
GO:1900186	biolink:NamedThing	negative regulation of clathrin-dependent endocytosis	Any process that stops, prevents or reduces the frequency, rate or extent of clathrin-mediated endocytosis.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of clathrin coated pit-dependent endocytosis|inhibition of clathrin coated pit-dependent endocytosis|down-regulation of clathrin-mediated endocytosis|downregulation of clathrin-mediated endocytosis|down regulation of clathrin-mediated endocytosis|downregulation of clathrin coated pit-dependent endocytosis|inhibition of clathrin-mediated endocytosis|inhibition of clathrin-dependent endocytosis|down-regulation of clathrin coated pit-dependent endocytosis|down regulation of clathrin-dependent endocytosis|downregulation of clathrin-dependent endocytosis|down regulation of clathrin coated pit-dependent endocytosis|down-regulation of clathrin-dependent endocytosis|negative regulation of clathrin-mediated endocytosis							hjd	2012-03-16T05:25:02Z					biological_process											owl:Class	
GO:0048261	biolink:NamedThing	negative regulation of receptor-mediated endocytosis	Any process that stops, prevents, or reduces the frequency, rate or extent of receptor mediated endocytosis, the uptake of external materials by cells, utilizing receptors to ensure specificity of transport.	tmpzr1t_l9r_go_relaxed.owl	downregulation of receptor mediated endocytosis|inhibition of receptor mediated endocytosis|down-regulation of receptor mediated endocytosis|negative regulation of receptor mediated endocytosis|down regulation of receptor mediated endocytosis													biological_process											owl:Class	
GO:1901215	biolink:NamedThing	negative regulation of neuron death	Any process that stops, prevents or reduces the frequency, rate or extent of neuron death.	tmpzr1t_l9r_go_relaxed.owl	inhibition of neuron cell death|inhibition of neuronal cell death|inhibition of neuron death|negative regulation of neuron cell death|negative regulation of neuronal cell death|down regulation of neuron death|down-regulation of neuron cell death|downregulation of neuron cell death|downregulation of neuron death|down regulation of neuron cell death|down regulation of neuronal cell death|down-regulation of neuron death|down-regulation of neuronal cell death|downregulation of neuronal cell death							rph	2012-08-02T09:58:07Z					biological_process											owl:Class	
GO:0018351	biolink:NamedThing	peptidyl-cysteine esterification	The addition of an ester group to a cysteine residue in a protein.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0002140	biolink:NamedThing	stereocilia tip link	A stereocilia link that is formed by a fine filament running more or less vertically upward from the tip of each shorter stereocilium to attach at a higher point on its adjacent taller neighbor. Tilting the bundle puts tension on the filaments, which pull on mechanically gated ion channels in the membrane of the stereocilia.	tmpzr1t_l9r_go_relaxed.owl								hjd	2009-05-06T10:28:10Z					cellular_component											owl:Class	
GO:0002139	biolink:NamedThing	stereocilia coupling link	A structure involved in coupling stereocilia to one another in sensory hair cells There are four morphologically distinct types: tip links, horizontal top connectors, shaft connectors and ankle links. Tip links and horizontal top connectors are the only inter-stereocilia links associated with mature cochlea, whereas ankle links appear during development of the auditory hair bundle.	tmpzr1t_l9r_go_relaxed.owl								hjd	2009-05-06T10:25:38Z					cellular_component											owl:Class	
GO:0010205	biolink:NamedThing	photoinhibition	The mechanism by which high light intensity inhibits photosynthesis through inactivation of the D1 protein of photosystem II.	tmpzr1t_l9r_go_relaxed.owl	photosystem II inhibition				Wikipedia:Photoinhibition									biological_process											owl:Class	
GO:0009644	biolink:NamedThing	response to high light intensity	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a high light intensity stimulus.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1990360	biolink:NamedThing	PKM2 protein kinase complex	A protein complex capable of phosphorylating a large number of protein targets. Contributes to cell proliferation under glycose starvation conditions. In human, the complex is present as a dimer.	tmpzr1t_l9r_go_relaxed.owl	PKM2-SAICAR complex|PKM2-SAICAR protein kinase complex							bhm	2014-04-17T14:03:36Z					cellular_component											owl:Class	
GO:1900124	biolink:NamedThing	negative regulation of nodal receptor complex assembly	Any process that stops, prevents or reduces the frequency, rate or extent of nodal receptor complex assembly.	tmpzr1t_l9r_go_relaxed.owl	down regulation of nodal receptor complex formation|negative regulation of ActRIIB.ALK4.EGF-CFC complex formation|downregulation of nodal receptor complex assembly|down-regulation of ActRIIB.ALK4.EGF-CFC complex formation|down-regulation of nodal receptor complex formation|down regulation of nodal receptor complex assembly|inhibition of ActRIIB.ALK4.EGF-CFC complex formation|down regulation of ActRIIB.ALK4.EGF-CFC complex formation|downregulation of nodal receptor complex formation|downregulation of ActRIIB.ALK4.EGF-CFC complex formation|inhibition of nodal receptor complex assembly|negative regulation of nodal receptor complex formation|inhibition of nodal receptor complex formation|down-regulation of nodal receptor complex assembly							bf	2012-02-22T04:21:53Z					biological_process											owl:Class	
GO:0034234	biolink:NamedThing	regulation of ascospore wall chitin catabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of ascospore wall chitin.	tmpzr1t_l9r_go_relaxed.owl	regulation of ascospore wall chitin breakdown|regulation of ascospore wall chitin degradation|regulation of ascospore wall chitin catabolism													biological_process											owl:Class	
GO:0060200	biolink:NamedThing	clathrin-sculpted acetylcholine transport vesicle	A clathrin-sculpted lipid bilayer membrane-enclosed vesicle after clathrin release and containing acetylcholine.	tmpzr1t_l9r_go_relaxed.owl	clathrin sculpted acetylcholine constitutive secretory pathway transport vesicle|clathrin sculpted acetylcholine transport vesicle													cellular_component											owl:Class	
GO:0060908	biolink:NamedThing	plasmid copy number maintenance	The maintenance of the number of copies of extrachromosomal plasmid DNA.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-09-04T02:49:08Z					biological_process											owl:Class	
GO:0006276	biolink:NamedThing	plasmid maintenance	The maintenance of the integrity of extrachromosomal plasmid DNA; includes processes that ensure plasmids are retained in the daughter cells after cell division.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1902621	biolink:NamedThing	actomyosin contractile ring disassembly	The disaggregation of an actomyosin contractile ring into its constituent components.	tmpzr1t_l9r_go_relaxed.owl	cytokinetic ring disassembly|CAR disassembly|contractile actomyosin ring disassembly|constriction ring disassembly|actomyosin ring disassembly							mah	2014-01-15T09:27:26Z					biological_process											owl:Class	
GO:1900693	biolink:NamedThing	negative regulation of (+)-kotanin biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of (+)-kotanin biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	downregulation of (+)-kotanin anabolism|downregulation of (+)-kotanin synthesis|down regulation of (+)-kotanin formation|downregulation of (+)-kotanin biosynthetic process|down-regulation of (+)-kotanin biosynthesis|downregulation of (+)-kotanin biosynthesis|negative regulation of (+)-kotanin synthesis|negative regulation of (+)-kotanin formation|down-regulation of (+)-kotanin formation|down regulation of (+)-kotanin anabolism|inhibition of (+)-kotanin biosynthesis|down regulation of (+)-kotanin biosynthesis|negative regulation of (+)-kotanin biosynthesis|inhibition of (+)-kotanin formation|negative regulation of (+)-kotanin anabolism|down-regulation of (+)-kotanin biosynthetic process|down regulation of (+)-kotanin biosynthetic process|inhibition of (+)-kotanin anabolism|inhibition of (+)-kotanin synthesis|inhibition of (+)-kotanin biosynthetic process|down regulation of (+)-kotanin synthesis|down-regulation of (+)-kotanin synthesis|downregulation of (+)-kotanin formation|down-regulation of (+)-kotanin anabolism							di	2012-05-22T04:53:26Z					biological_process											owl:Class	
GO:0051971	biolink:NamedThing	positive regulation of transmission of nerve impulse	Any process that activates, maintains or increases the frequency, rate or extent of transmission of a nerve impulse, the sequential electrochemical polarization and depolarization that travels across the membrane of a neuron in response to stimulation.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of conduction of nerve impulse|upregulation of transmission of nerve impulse|stimulation of transmission of nerve impulse|up-regulation of transmission of nerve impulse|up regulation of transmission of nerve impulse|activation of transmission of nerve impulse													biological_process											owl:Class	
GO:0031646	biolink:NamedThing	positive regulation of nervous system process	Any process that activates or increases the frequency, rate or extent of a neurophysiological process.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of neurological process|up-regulation of neurological process|positive regulation of neurological system process|stimulation of neurological process|upregulation of neurological process|positive regulation of neurophysiological process|up regulation of neurological process|activation of neurological process													biological_process											owl:Class	
GO:0000285	biolink:NamedThing	1-phosphatidylinositol-3-phosphate 5-kinase activity	Catalysis of the reaction: a 1-phosphatidyl-1D-myo-inositol 3-phosphate + ATP = a 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate + ADP + 2 H(+).	tmpzr1t_l9r_go_relaxed.owl	type III PIP kinase activity|ATP:1-phosphatidyl-1D-myo-inositol-3-phosphate 5-phosphotransferase activity|phosphatidylinositol-3-phosphate 5-kinase activity|phosphatidylinositol 3-phosphate 5-kinase activity				MetaCyc:2.7.1.150-RXN|RHEA:13609|Reactome:R-HSA-1675921|EC:2.7.1.150|Reactome:R-HSA-1675910|Reactome:R-HSA-1676168|KEGG_REACTION:R05802|Reactome:R-HSA-1676134									molecular_function											owl:Class	
GO:0016307	biolink:NamedThing	phosphatidylinositol phosphate kinase activity	Catalysis of the reaction: ATP + a phosphatidylinositol phosphate = ADP + a phosphatidylinositol bisphosphate.	tmpzr1t_l9r_go_relaxed.owl	phosphatidylinositol monophosphate kinase activity													molecular_function											owl:Class	
GO:0090264	biolink:NamedThing	regulation of immune complex clearance by monocytes and macrophages	Any process that modulates the rate, frequency, or extent of the process of immune complex clearance by monocytes or macrophages.	tmpzr1t_l9r_go_relaxed.owl								tb	2010-02-04T04:31:29Z					biological_process											owl:Class	
GO:0035299	biolink:NamedThing	inositol pentakisphosphate 2-kinase activity	Catalysis of the reaction: 1D-myo-inositol 1,3,4,5,6-pentakisphosphate + ATP = 1D-myo-inositol hexakisphosphate + ADP + 2 H(+).	tmpzr1t_l9r_go_relaxed.owl	Ipk1p|inositol-pentakisphosphate 2-kinase activity|ATP:1D-myo-inositol 1,3,4,5,6-pentakisphosphate 2-phosphotransferase activity|inositol polyphosphate kinase activity|IP5 2-kinase activity|Ins(1,3,4,5,6)P5 2-kinase activity|Gsl1p|inositol 1,3,4,5,6-pentakisphosphate 2-kinase activity|inositol hexakisphosphate synthase				RHEA:20313|KEGG_REACTION:R05202|EC:2.7.1.158|MetaCyc:RXN-7163|Reactome:R-HSA-1855176|Reactome:R-HSA-1855179									molecular_function											owl:Class	
GO:0072308	biolink:NamedThing	negative regulation of metanephric nephron tubule epithelial cell differentiation	Any process that decreases the frequency, rate or extent of metanephric nephron tubule epithelial cell differentiation.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-04-09T05:03:41Z					biological_process											owl:Class	
GO:0072183	biolink:NamedThing	negative regulation of nephron tubule epithelial cell differentiation	Any process that decreases the frequency, rate or extent of nephron tubule epithelial cell differentiation.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-02-26T02:47:25Z					biological_process											owl:Class	
GO:2001035	biolink:NamedThing	regulation of tongue muscle cell differentiation	Any process that modulates the frequency, rate or extent of tongue muscle cell differentiation.	tmpzr1t_l9r_go_relaxed.owl								yaf	2011-08-24T11:10:16Z					biological_process											owl:Class	
GO:0009356	biolink:NamedThing	aminodeoxychorismate synthase complex	A heterodimeric protein complex that possesses 4-amino-4-deoxychorismate synthase activity.	tmpzr1t_l9r_go_relaxed.owl	ADC synthase complex|4-amino-4-deoxychorismate synthase complex|p-aminobenzoate synthetase complex													cellular_component											owl:Class	
GO:0060976	biolink:NamedThing	coronary vasculature development	The process whose specific outcome is the progression of the blood vessels of the heart over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl	cardiac blood vessel development|heart vasculature development|coronary blood vessel development|cardiac vasculature development|heart blood vessel development							dph	2009-10-06T12:15:23Z					biological_process											owl:Class	
GO:0102848	biolink:NamedThing	1-18:2-2-18:2-digalactosyldiacylglycerol desaturase activity	Catalysis of the reaction: 1-18:2-2-18:2-digalactosyldiacylglycerol + O2 + a reduced electron acceptor <=> 1-18:3-2-18:2-digalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-8310|EC:1.14.19.35									molecular_function											owl:Class	
GO:0071144	biolink:NamedThing	heteromeric SMAD protein complex	A protein complex composed of SMAD family proteins, a transcription factor complex which binds to the promoters of target genes and recruits co-activators and histone acetyltransferases, facilitating transcription. Phosphorylation of the non-SMAD4 subunit(s) enables binding of SMAD4 to form heteromeric complexes that enter the nucleus to initiate gene transcription. DNA-binding specificity is conferred by other transcription factors binding to SMAD complexes. Interactions with coactivators or corepressors modulate their transcriptional activity. Can be heterotrimeric or heterodimeric.	tmpzr1t_l9r_go_relaxed.owl	SMAD2-SMAD3-SMAD4 protein complex|SMAD3-SMAD4 protein complex|SMAD2-SMAD4 protein complex|SMAD1-SMAD4 protein complex								2009-11-16T02:44:37Z			GO:0071146|GO:0071145		cellular_component											owl:Class	
GO:0061639	biolink:NamedThing	Cdv-dependent cytokinesis	A cytokinesis that involves a set of conserved proteins including the Cdv proteins, and results in the formation of two similarly sized and shaped cells.	tmpzr1t_l9r_go_relaxed.owl								dph	2014-08-21T14:55:04Z					biological_process											owl:Class	
GO:0071646	biolink:NamedThing	regulation of macrophage inflammatory protein-1 gamma production	Any process that modulates the frequency, rate, or extent of production of macrophage inflammatory protein-1 gamma.	tmpzr1t_l9r_go_relaxed.owl	regulation of MIP-1g production|regulation of CCL9 production|regulation of chemokine (C-C motif) ligand 9 production							mah	2010-02-12T10:40:19Z					biological_process											owl:Class	
GO:0046310	biolink:NamedThing	1,3-dichloro-2-propanol catabolic process	The chemical reactions and pathways resulting in the breakdown of 1,3-dichloro-2-propanol (DCP), a halohydrin suspected of being carcinogenic, mutagenic and genotoxic.	tmpzr1t_l9r_go_relaxed.owl	1,3-dichloro-2-propanol breakdown|1,3-dichloro-2-propanol catabolism|1,3-dichloro-2-propanol degradation													biological_process											owl:Class	
GO:0044109	biolink:NamedThing	cellular alcohol catabolic process	The chemical reactions and pathways resulting in the breakdown of alcohols, any of a class of compounds containing one or more hydroxyl groups attached to a saturated carbon atom, occurring at the level of the individual cell.	tmpzr1t_l9r_go_relaxed.owl								jl	2009-07-15T01:44:27Z					biological_process											owl:Class	
GO:0019551	biolink:NamedThing	glutamate catabolic process to 2-oxoglutarate	The chemical reactions and pathways resulting in the breakdown of glutamate into other compounds, including 2-oxoglutarate.	tmpzr1t_l9r_go_relaxed.owl	glutamate catabolism to alpha-ketoglutarate|glutamate breakdown to 2-oxoglutarate|glutamate catabolic process to alpha-oxoglutarate|glutamate catabolism to 2-ketoglutarate|glutamate catabolism to alpha-oxoglutarate|glutamate catabolic process to 2-ketoglutarate|glutamate catabolic process to alpha-ketoglutarate|glutamate degradation to 2-oxoglutarate				MetaCyc:PWY-5766|MetaCyc:GLUTAMATE-DEG1-PWY									biological_process											owl:Class	
GO:0006103	biolink:NamedThing	2-oxoglutarate metabolic process	The chemical reactions and pathways involving oxoglutarate, the dianion of 2-oxoglutaric acid. It is a key constituent of the TCA cycle and a key intermediate in amino-acid metabolism.	tmpzr1t_l9r_go_relaxed.owl	2-ketoglutarate metabolic process|2-oxoglutarate metabolism|alpha-oxoglutarate metabolism|alpha-ketoglutarate metabolism|alpha-oxoglutarate metabolic process|2-ketoglutarate metabolism|alpha-ketoglutarate metabolic process													biological_process											owl:Class	
GO:0102698	biolink:NamedThing	5-epi-aristolochene synthase activity	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate <=> (+)-5-epi-aristolochene + diphosphoric acid.	tmpzr1t_l9r_go_relaxed.owl					EC:4.2.3.61|RHEA:28635|MetaCyc:RXN-4781									molecular_function											owl:Class	
GO:0045134	biolink:NamedThing	uridine-diphosphatase activity	Catalysis of the reaction: UDP + H2O = UMP + phosphate.	tmpzr1t_l9r_go_relaxed.owl	UDP phosphohydrolase activity|uridine diphosphatase activity|uridine 5'-diphosphatase activity|UDPase activity				KEGG_REACTION:R00155|MetaCyc:RXN-12197|RHEA:64876|EC:3.6.1.6									molecular_function											owl:Class	
GO:0004878	biolink:NamedThing	complement component C5a receptor activity	Combining with the C5a product of the complement cascade and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	C5a anaphylatoxin receptor activity											GO:0004944		molecular_function											owl:Class	
GO:0046772	biolink:NamedThing	viral budding from outer nuclear membrane	The envelopment of a virus, in which the naked capsid evaginates from the host outer nuclear membrane system, thus acquiring a membrane envelope.	tmpzr1t_l9r_go_relaxed.owl	virus budding from outer nuclear membrane during viral capsid envelopment|outer nuclear membrane viral budding during viral capsid envelopment|virus budding from outer nuclear membrane by viral capsid envelopment|viral budding from outer nuclear membrane during viral capsid envelopment	https://github.com/geneontology/go-ontology/issues/20782												biological_process											owl:Class	
GO:0060292	biolink:NamedThing	long-term synaptic depression	A process that modulates synaptic plasticity such that synapses are changed resulting in the decrease in the rate, or frequency of synaptic transmission at the synapse.	tmpzr1t_l9r_go_relaxed.owl	long term depression|LTD|long term synaptic depression													biological_process											owl:Class	
GO:0061301	biolink:NamedThing	cerebellum vasculature morphogenesis	The process in which the vasculature of the cerebellum is generated and organized.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-09-06T03:38:05Z					biological_process											owl:Class	
GO:1900758	biolink:NamedThing	negative regulation of D-amino-acid oxidase activity	Any process that stops, prevents or reduces the frequency, rate or extent of D-amino-acid oxidase activity.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of L-amino acid:O2 oxidoreductase activity|negative regulation of D-amino-acid:oxygen oxidoreductase (deaminating)|downregulation of new yellow enzyme|down regulation of D-amino-acid oxidase activity|downregulation of D-amino-acid oxidase activity|down-regulation of new yellow enzyme|down-regulation of L-amino acid:O2 oxidoreductase activity|down-regulation of D-amino-acid oxidase activity|downregulation of D-amino-acid:oxygen oxidoreductase (deaminating)|inhibition of L-amino acid:O2 oxidoreductase activity|downregulation of L-amino acid:O2 oxidoreductase activity|down regulation of L-amino acid:O2 oxidoreductase activity|negative regulation of new yellow enzyme|inhibition of new yellow enzyme|down-regulation of D-amino-acid:oxygen oxidoreductase (deaminating)|inhibition of D-amino-acid oxidase activity|down regulation of new yellow enzyme|inhibition of D-amino-acid:oxygen oxidoreductase (deaminating)|down regulation of D-amino-acid:oxygen oxidoreductase (deaminating)							pm	2012-05-31T11:24:06Z					biological_process											owl:Class	
GO:0019316	biolink:NamedThing	D-allose catabolic process	The chemical reactions and pathways resulting in the breakdown of D-allose, the D-enantiomer of allo-hexose, an aldohexose similar to glucose.	tmpzr1t_l9r_go_relaxed.owl	D-allose degradation|D-allose catabolism|D-allose breakdown				MetaCyc:PWY0-44									biological_process											owl:Class	
GO:0019314	biolink:NamedThing	D-allose metabolic process	The chemical reactions and pathways involving D-allose, the D-enantiomer of allo-hexose, an aldohexose similar to glucose.	tmpzr1t_l9r_go_relaxed.owl	D-allose metabolism													biological_process											owl:Class	
GO:0004439	biolink:NamedThing	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity	Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H(2)O = 1-phosphatidyl-1D-myo-inositol 4-phosphate + phosphate.	tmpzr1t_l9r_go_relaxed.owl	phosphatidyl-myo-inositol-4,5-bisphosphate phosphatase activity|phosphatidylinositol-bisphosphatase activity|PI(4,5)P2 5-phosphatase activity|PtdIns(4,5)P(2) 5-phosphatase activity|triphosphoinositide phosphatase activity|phosphatidylinositol 4,5-bisphosphate phosphatase activity|PtdIns(4,5)P2 5-phosphatase activity|triphosphoinositide phosphomonoesterase activity				RHEA:22764|Reactome:R-HSA-8868648|KEGG_REACTION:R04404|Reactome:R-HSA-1675824|EC:3.1.3.36|MetaCyc:PHOSPHATIDYLINOSITOL-BISPHOSPHATASE-RXN|Reactome:R-HSA-1676177							GO:0001668		molecular_function											owl:Class	
GO:0034595	biolink:NamedThing	phosphatidylinositol phosphate 5-phosphatase activity	Catalysis of the removal of the 5-phosphate group of a phosphatidylinositol phosphate.	tmpzr1t_l9r_go_relaxed.owl	phosphoinositide 5-phosphatase activity|polyphosphoinositol lipid 5-phosphatase activity													molecular_function											owl:Class	
GO:0031141	biolink:NamedThing	induction of conjugation upon carbon starvation	The process in which a cell initiates conjugation with cellular fusion upon carbon starvation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0031140	biolink:NamedThing	induction of conjugation upon nutrient starvation	The process in which a cell initiates conjugation with cellular fusion upon starvation for one or more nutrients.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0034149	biolink:NamedThing	positive regulation of toll-like receptor 5 signaling pathway	Any process that activates or increases the frequency, rate, or extent of toll-like receptor 5 signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of TLR5 signaling pathway|positive regulation of toll-like receptor 5 signalling pathway													biological_process											owl:Class	
GO:0034010	biolink:NamedThing	sulfolactate sulfo-lyase activity	Catalysis of the reaction: 3-sulfolactate = pyruvate + sulfite.	tmpzr1t_l9r_go_relaxed.owl	3-sulfolactate bisulfite-lyase (pyruvate-forming) activity|3-sulfolactate bisulfite-lyase activity|SuyAB|Suy				MetaCyc:4.4.1.24-RXN|EC:4.4.1.24|RHEA:21428|KEGG_REACTION:R07633									molecular_function											owl:Class	
GO:1904064	biolink:NamedThing	positive regulation of cation transmembrane transport	Any process that activates or increases the frequency, rate or extent of cation transmembrane transport.	tmpzr1t_l9r_go_relaxed.owl	up regulation of cation transmembrane transport|up-regulation of cation transmembrane transport|upregulation of cation transmembrane transport|activation of cation transmembrane transport							sl	2015-03-18T21:11:55Z					biological_process											owl:Class	
GO:0015518	biolink:NamedThing	arabinose:proton symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: arabinose(out) + H+(out) = arabinose(in) + H+(in).	tmpzr1t_l9r_go_relaxed.owl	arabinose:hydrogen symporter activity|arabinose efflux transmembrane transporter activity|arabinose efflux permease activity											GO:0015523		molecular_function											owl:Class	
GO:0000410	biolink:NamedThing	carbon catabolite repression of transcription by galactose	A transcription regulation process in which the presence of galactose that leads to a decrease in the frequency, rate, or extent of transcription of specific genes involved in the metabolism of other carbon sources. Carbon catabolite repression is a mechanism of genetic regulation which the accumulation of catabolites of one substance in the cell represses the formation of enzymes that contribute to the catabolism of other substances.	tmpzr1t_l9r_go_relaxed.owl	inhibition of transcription by galactose|downregulation of transcription by galactose|down regulation of transcription by galactose|down-regulation of transcription by galactose													biological_process											owl:Class	
GO:0000409	biolink:NamedThing	regulation of transcription by galactose	Any process involving galactose that modulates the frequency, rate or extent or transcription.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1901398	biolink:NamedThing	regulation of transforming growth factor beta3 activation	Any process that modulates the frequency, rate or extent of transforming growth factor beta3 activation.	tmpzr1t_l9r_go_relaxed.owl	regulation of TGFbeta 3 activation|regulation of TGFB3 activation|regulation of TGF-beta 3 activation							bf	2012-10-01T10:49:25Z					biological_process											owl:Class	
GO:0045829	biolink:NamedThing	negative regulation of isotype switching	Any process that stops, prevents, or reduces the frequency, rate or extent of isotype switching.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of isotype switch recombination|negative regulation of class switching|negative regulation of class switch recombination|down regulation of isotype switching|down-regulation of isotype switching|inhibition of isotype switching|downregulation of isotype switching													biological_process											owl:Class	
GO:1901650	biolink:NamedThing	positive regulation of actomyosin contractile ring localization	Any process that activates or increases the frequency, rate or extent of actomyosin contractile ring localization.	tmpzr1t_l9r_go_relaxed.owl	up regulation of actomyosin contractile ring localization|activation of contractile ring localization involved in cell cycle cytokinesis|upregulation of contractile ring localization involved in cell cycle cytokinesis|up-regulation of contractile ring localisation involved in cell cycle cytokinesis|upregulation of actomyosin contractile ring localization|activation of contractile ring localisation involved in cell cycle cytokinesis|up-regulation of contractile ring localization involved in cell cycle cytokinesis|up regulation of contractile ring localization involved in cell cycle cytokinesis|positive regulation of contractile ring localization involved in cell cycle cytokinesis|positive regulation of contractile ring localisation involved in cell cycle cytokinesis|up regulation of contractile ring localisation involved in cell cycle cytokinesis|up-regulation of actomyosin contractile ring localization|activation of actomyosin contractile ring localization|upregulation of contractile ring localisation involved in cell cycle cytokinesis							vw	2012-11-19T13:42:54Z					biological_process											owl:Class	
GO:2000845	biolink:NamedThing	positive regulation of testosterone secretion	Any process that activates or increases the frequency, rate or extent of testosterone secretion.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-07-26T08:42:36Z					biological_process											owl:Class	
GO:0045966	biolink:NamedThing	positive regulation of ecdysteroid metabolic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving ecdysteroids.	tmpzr1t_l9r_go_relaxed.owl	activation of ecdysteroid metabolic process|up regulation of ecdysteroid metabolic process|positive regulation of ecdysteroid metabolism|upregulation of ecdysteroid metabolic process|stimulation of ecdysteroid metabolic process|up-regulation of ecdysteroid metabolic process													biological_process											owl:Class	
GO:0061453	biolink:NamedThing	interstitial cell of Cajal differentiation	The process in which a relatively unspecialized cell acquires specialized features of an interstitial cell of Cajal. An interstitial cell of Cajal is an intestinal neuroepithelial cell that serves as a pacemaker to trigger gut contraction.	tmpzr1t_l9r_go_relaxed.owl	ICC differentiation							dph	2012-07-20T08:20:50Z					biological_process											owl:Class	
GO:0035010	biolink:NamedThing	encapsulation of foreign target	Events resulting in the formation of a multilayered cellular sheath surrounding an invader and thus preventing its development. This defense mechanism is often seen in insects in response to nematodes or parasitoids, which are too large to be phagocytosed by individual hemocytes. In some organisms the capsule is blackened due to melanization.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:2000908	biolink:NamedThing	positive regulation of glucomannan catabolic process	Any process that activates or increases the frequency, rate or extent of glucomannan catabolic process.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of glucomannan catabolism							tt	2011-07-29T01:13:30Z					biological_process											owl:Class	
GO:0007176	biolink:NamedThing	regulation of epidermal growth factor-activated receptor activity	Any process that modulates the frequency, rate or extent of EGF-activated receptor activity.	tmpzr1t_l9r_go_relaxed.owl	regulation of EGF receptor activity|regulation of epidermal growth factor receptor activity|regulation of EGFR activity													biological_process											owl:Class	
GO:1901210	biolink:NamedThing	regulation of cardiac chamber formation	Any process that modulates the frequency, rate or extent of cardiac chamber formation.	tmpzr1t_l9r_go_relaxed.owl	regulation of heart chamber formation							rl	2012-07-31T07:18:35Z					biological_process											owl:Class	
GO:0061376	biolink:NamedThing	mammillotegmental axonal tract development	The process in which the mammillotegmental tract progresses over time, from its formation to the mature structure. The mammillotegmental tract is the collection of axons that connects the ventral diencephalon to the tegmentum and pons.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-11-09T09:09:29Z					biological_process											owl:Class	
GO:2001021	biolink:NamedThing	negative regulation of response to DNA damage stimulus	Any process that stops, prevents or reduces the frequency, rate or extent of response to DNA damage stimulus.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of response to genotoxic stress|negative regulation of cellular DNA damage response|negative regulation of cellular response to DNA damage stimulus|negative regulation of DNA damage response							yaf	2011-08-19T10:20:29Z					biological_process											owl:Class	
GO:0033174	biolink:NamedThing	chloroplast proton-transporting ATP synthase complex, catalytic core CF(1)	The catalytic sector of the mitochondrial hydrogen-transporting ATP synthase; it comprises the catalytic core and central stalk, and is peripherally associated with the chloroplast thylakoid membrane when the entire ATP synthase is assembled. The chloroplast F0 domain contains three alpha, three beta, one gamma, one delta, and one epsilon subunits.	tmpzr1t_l9r_go_relaxed.owl	chloroplast proton-transporting F-type ATPase complex, catalytic core CF(1)													cellular_component											owl:Class	
GO:2001189	biolink:NamedThing	negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell	Any process that stops, prevents or reduces the frequency, rate or extent of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of T lymphocyte activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell|negative regulation of T-lymphocyte activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell|negative regulation of T-cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell							yaf	2011-11-03T01:31:36Z					biological_process											owl:Class	
GO:0050907	biolink:NamedThing	detection of chemical stimulus involved in sensory perception	The series of events in which a chemical stimulus is received and converted into a molecular signal as part of sensory perception.	tmpzr1t_l9r_go_relaxed.owl	sensory perception, sensory detection of chemical stimulus|sensory detection of chemical stimulus|sensory transduction of chemical stimulus|sensory transduction of chemical stimulus during sensory perception|sensory perception, sensory transduction of chemical stimulus|sensory detection of chemical stimulus during sensory perception													biological_process											owl:Class	
GO:0019242	biolink:NamedThing	methylglyoxal biosynthetic process	The chemical reactions and pathways resulting in the formation of methylglyoxal, CH3-CO-CHO, the aldehyde of pyruvic acid.	tmpzr1t_l9r_go_relaxed.owl	methylglyoxal biosynthesis|methylglyoxal formation|methylglyoxal anabolism|methylglyoxal synthesis													biological_process											owl:Class	
GO:0052889	biolink:NamedThing	9,9'-di-cis-zeta-carotene desaturation to 7,9,7',9'-tetra-cis-lycopene	The series of reactions in which 9,9'-di-cis-zeta-carotene is desaturated to 7,9,9'-tri-cis-neurosporene, and then 7,9,7',9'-tetra-cis-lycopene. The overall reaction for this process is: 9,9'-di-cis-zeta-carotene + 2 quinone = 2 quinol + 7,9,7',9'-tetra-cis-lycopene.	tmpzr1t_l9r_go_relaxed.owl	9,9'-di-cis-zeta-carotene catabolism to 7,9,7',9'-tetra-cis-lycopene|7,9,7',9'-tetra-cis-lycopene biosynthesis from 9,9'-di-cis-zeta-carotene				KEGG_REACTION:R07511|MetaCyc:RXN-12242									biological_process											owl:Class	
GO:0019247	biolink:NamedThing	lactate racemization	Partial conversion of one lactate enantiomer into another so that the specific optical rotation is decreased, or even reduced to zero, in the resulting mixture.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0019507	biolink:NamedThing	pyridine metabolic process	The chemical reactions and pathways involving pyridine, a nitrogenous base (C5H5N) obtained from the distillation of bone oil or coal tar, and by the decomposition of certain alkaloids, as a colorless liquid with a peculiar pungent odor.	tmpzr1t_l9r_go_relaxed.owl	pyridine metabolism													biological_process											owl:Class	
GO:0045695	biolink:NamedThing	negative regulation of embryo sac egg cell differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of embryo sac egg cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	downregulation of female gametophyte egg cell differentiation|down regulation of female gametophyte egg cell differentiation|negative regulation of female gametophyte egg cell differentiation|inhibition of female gametophyte egg cell differentiation|down-regulation of female gametophyte egg cell differentiation													biological_process											owl:Class	
GO:0045694	biolink:NamedThing	regulation of embryo sac egg cell differentiation	Any process that modulates the frequency, rate or extent of embryo sac egg cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	regulation of female gametophyte egg cell differentiation													biological_process											owl:Class	
GO:0060723	biolink:NamedThing	regulation of cell proliferation involved in embryonic placenta development	Any process that modulates the rate, frequency, or extent of cell proliferation involved in embryonic placenta development.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-06-12T12:50:23Z					biological_process											owl:Class	
GO:0062075	biolink:NamedThing	pollen aperture formation	The cellular component assembly process of forming pollen apertures, areas where exine is reduced or absent, in the pollen cell wall.	tmpzr1t_l9r_go_relaxed.owl								dph	2018-09-19T19:25:59Z					biological_process											owl:Class	
GO:0051063	biolink:NamedThing	CDP reductase activity	Catalysis of the reaction: dCDP + thioredoxin disulfide + H2O = CDP + thioredoxin.	tmpzr1t_l9r_go_relaxed.owl	CDP reduction				MetaCyc:CDPREDUCT-RXN									molecular_function											owl:Class	
GO:0106007	biolink:NamedThing	microtubule anchoring at cell cortex of cell tip	Any process in which a microtubule is maintained in a specific location at the cell tip by attachment to the cell cortex.	tmpzr1t_l9r_go_relaxed.owl								hjd	2017-04-19T15:12:45Z					biological_process											owl:Class	
GO:0034453	biolink:NamedThing	microtubule anchoring	Any process in which a microtubule is maintained in a specific location in a cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0071601	biolink:NamedThing	sphere organelle	A nuclear body that is found in the germinal vesicles of amphibian oocytes, and consist of three major parts: a remarkably spherical body about 5-10 pm in diameter, smaller spherical or nearly spherical granules on the surface, and inclusions of various sizes that strongly resemble the surface granules. The parts of the sphere organelle have distinct compositions, including splicing snRNAs and proteins.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-02-04T04:26:41Z					cellular_component											owl:Class	
GO:0097685	biolink:NamedThing	dinoflagellate apical groove	A cell surface furrow (or groove) found on a dinoflagellate apex. It typically loops around the apex.	tmpzr1t_l9r_go_relaxed.owl	apical groove					The term name refers to a taxonomic group to make the label unique with respect to similarly-named anatomical structures.		pr	2014-12-18T09:34:52Z					cellular_component											owl:Class	
GO:0097610	biolink:NamedThing	cell surface furrow	A furrow that may be found on the cell surface. Examples include the cingulum and sulcus found in some dinoflagellates.	tmpzr1t_l9r_go_relaxed.owl	cell surface groove|groove|furrow							pr	2014-06-09T11:22:38Z					cellular_component											owl:Class	
GO:1905029	biolink:NamedThing	positive regulation of membrane depolarization during AV node cell action potential	Any process that activates or increases the frequency, rate or extent of membrane depolarization during AV node cell action potential.	tmpzr1t_l9r_go_relaxed.owl	activation of membrane depolarization during AV node cardiac muscle cell action potential|positive regulation of membrane depolarization during atrioventricular node cardiac muscle cell action potential|up-regulation of membrane depolarization during atrioventricular node cardiac muscle cell action potential|up regulation of membrane depolarization during AV node cell action potential|up-regulation of membrane depolarization during AV node cardiac muscle cell action potential|up regulation of membrane depolarization during AV node cardiac muscle cell action potential|positive regulation of membrane depolarization during AV node cardiac muscle cell action potential|upregulation of membrane depolarization during AV node cell action potential|up-regulation of membrane depolarization during AV node cell action potential|upregulation of membrane depolarization during AV node cardiac muscle cell action potential|activation of membrane depolarization during atrioventricular node cardiac muscle cell action potential|upregulation of membrane depolarization during atrioventricular node cardiac muscle cell action potential|up regulation of membrane depolarization during atrioventricular node cardiac muscle cell action potential|activation of membrane depolarization during AV node cell action potential							rph	2016-03-04T13:46:24Z					biological_process											owl:Class	
GO:0050418	biolink:NamedThing	hydroxylamine reductase activity	Catalysis of the reaction: NH3 + H2O + acceptor = hydroxylamine + reduced acceptor.	tmpzr1t_l9r_go_relaxed.owl	ammonia:acceptor oxidoreductase activity|ammonia:(acceptor) oxidoreductase activity|hydroxylamine (acceptor) reductase activity				RHEA:22052|MetaCyc:HYDROXYLAMINE-REDUCTASE-RXN|EC:1.7.99.1									molecular_function											owl:Class	
GO:0033639	biolink:NamedThing	modulation by symbiont of host response to water	Any process in which an organism modulates a change in state or activity of a host cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a water stimulus. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0000282	biolink:NamedThing	cellular bud site selection	The specification of the site where a daughter cell will form, in organisms that reproduce by budding. An example of this process is found in Saccharomyces cerevisiae.	tmpzr1t_l9r_go_relaxed.owl	bud site selection/establishment of cell polarity					Note that this term was split from 'bud site selection/establishment of cell polarity (sensu Saccharomyces) ; GO:0007115' (a sibling term, 'establishment of cell polarity (sensu Saccharomyces) ; GO:0000283', was created but has since been merged with 'establishment of cell polarity' ; GO:0030010).								biological_process											owl:Class	
GO:1905136	biolink:NamedThing	dethiobiotin import across plasma membrane	The directed movement of dethiobiotin from outside of a cell, across the plasma membrane and into the cytosol.	tmpzr1t_l9r_go_relaxed.owl	dethiobiotin import into cell|dethiobiotin import							jl	2012-12-06T13:06:28Z			GO:1901690|GO:0044757		biological_process											owl:Class	
GO:0031089	biolink:NamedThing	platelet dense granule lumen	The volume enclosed by the membrane of the platelet dense granule.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0051137	biolink:NamedThing	negative regulation of NK T cell differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer T cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of NK T cell development|negative regulation of natural killer T cell differentiation|downregulation of NK T cell differentiation|down-regulation of NK T cell differentiation|down regulation of NK T cell differentiation|negative regulation of natural T cell differentiation|negative regulation of NK T lymphocyte differentiation|negative regulation of NK T-lymphocyte differentiation|negative regulation of NT cell differentiation|inhibition of NK T cell differentiation|negative regulation of NKT cell differentiation|negative regulation of NK T-cell differentiation					Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.								biological_process											owl:Class	
GO:1990877	biolink:NamedThing	Lst4-Lst7 complex	A heterodimeric complex that functions as a GTPase-Activating Protein (GAP) Complex for members of the Rag family of GTPases. In the budding yeast, this complex contains Lst4 and Lst7, while the orthologous mammalian complex contains Follicular (FLCN) and either follicular interaction protein 1 (FNIP1) or FNIP2.	tmpzr1t_l9r_go_relaxed.owl	FLCN-FNIP2 complex|FLCN-FNIP1 complex|FNIP-Folliculin RagC/D GAP complex							rb	2015-10-01T22:44:58Z					cellular_component											owl:Class	
GO:1902773	biolink:NamedThing	GTPase activator complex	A protein complex which is capable of GTPase activator activity.	tmpzr1t_l9r_go_relaxed.owl						An example of this is BFA1 in Saccharomyces cerevisiae (P47113) in PMID:16449187 (inferred from direct assay).		bhm	2014-03-17T14:26:08Z					cellular_component											owl:Class	
GO:0062105	biolink:NamedThing	RNA 2'-O-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + RNA = S-adenosyl-L-homocysteine + RNA containing 2'-O-methylribonucleotide.	tmpzr1t_l9r_go_relaxed.owl					RHEA:58956			dph	2019-01-23T14:23:00Z					molecular_function											owl:Class	
GO:0005668	biolink:NamedThing	RNA polymerase transcription factor SL1 complex	A RNA polymerase I-specific transcription factor complex that contains the TATA-box-binding protein (TBP) and at least three TBP-associated factors including proteins known in mammals as TAFI110, TAFI63 and TAFI48.	tmpzr1t_l9r_go_relaxed.owl	selectivity factor SL1 complex|TIF-IB													cellular_component											owl:Class	
GO:1904568	biolink:NamedThing	cellular response to wortmannin	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a wortmannin stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to wartmannin							sl	2015-08-19T16:22:34Z					biological_process											owl:Class	
GO:1900567	biolink:NamedThing	chanoclavine-I aldehyde metabolic process	The chemical reactions and pathways involving chanoclavine-I aldehyde.	tmpzr1t_l9r_go_relaxed.owl	chanoclavine-I aldehyde metabolism							di	2012-05-15T06:31:00Z					biological_process											owl:Class	
GO:0099151	biolink:NamedThing	regulation of postsynaptic density assembly	Any process that modulates the frequency, rate or extent of postsynaptic density assembly, the aggregation, arrangement and bonding together of a set of components to form a postsynaptic density.	tmpzr1t_l9r_go_relaxed.owl								dos	2017-07-05T13:20:48Z					biological_process											owl:Class	
GO:0045453	biolink:NamedThing	bone resorption	The process in which specialized cells known as osteoclasts degrade the organic and inorganic portions of bone, and endocytose and transport the degradation products.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Bone_resorption									biological_process											owl:Class	
GO:1904009	biolink:NamedThing	cellular response to monosodium glutamate	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monosodium glutamate stimulus.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-03-06T18:26:40Z					biological_process											owl:Class	
GO:1904008	biolink:NamedThing	response to monosodium glutamate	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monosodium glutamate stimulus.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-03-06T18:26:34Z					biological_process											owl:Class	
GO:0004671	biolink:NamedThing	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + protein C-terminal S-farnesyl-L-cysteine = S-adenosyl-L-homocysteine + protein C-terminal S-farnesyl-L-cysteine methyl ester.	tmpzr1t_l9r_go_relaxed.owl	S-adenosyl-L-methionine:protein-C-terminal-S-farnesyl-L-cysteine O-methyltransferase activity|farnesyl-protein carboxymethyltransferase activity|prenylcysteine methyltransferase activity|prenylated protein methyltransferase activity|isoprenylated protein methyltransferase activity|prenylcysteine carboxymethyltransferase activity|protein S-farnesylcysteine C-terminal methyltransferase activity|farnesyl cysteine C-terminal methyltransferase activity|prenylated protein carboxyl methyltransferase activity|farnesylated protein C-terminal O-methyltransferase activity|isoprenylcysteine carboxylmethyltransferase activity|prenylcysteine carboxyl methyltransferase activity|protein-S-isoprenylcysteine O-methyltransferase activity|prenylcysteine carboxylmethyltransferase activity|protein C-terminal farnesylcysteine O-methyltransferase activity|S-farnesylcysteine methyltransferase activity				RHEA:21672|KEGG_REACTION:R04496|Reactome:R-HSA-9647977|MetaCyc:2.1.1.100-RXN|Reactome:R-HSA-6788650|EC:2.1.1.100							GO:0018225		molecular_function											owl:Class	
GO:0001735	biolink:NamedThing	prenylcysteine oxidase activity	Catalysis of the reaction: S-prenyl-L-cysteine + O2 + H2O = a prenal + L-cysteine + H2O2.	tmpzr1t_l9r_go_relaxed.owl	S-prenyl-L-cysteine:oxygen oxidoreductase activity|prenylcysteine lyase activity				EC:1.8.3.5|RHEA:53892|MetaCyc:1.8.3.5-RXN									molecular_function											owl:Class	
GO:0061790	biolink:NamedThing	dense core granule docking	The initial attachment of a dense core granule membrane to the plasma membrane.	tmpzr1t_l9r_go_relaxed.owl								dph	2016-09-08T15:51:49Z					biological_process											owl:Class	
GO:0052036	biolink:NamedThing	suppression by symbiont of host inflammatory response	Any process in which a symbiont stops, prevents, or reduces the frequency, rate or extent of the inflammatory response of the host organism; the inflammatory response is the immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	negative regulation by symbiont of host inflammatory response|down regulation by symbiont of host inflammatory response|inhibition by symbiont of host inflammatory response|negative regulation by organism of inflammatory response of other organism involved in symbiotic interaction|downregulation by symbiont of host inflammatory response|down-regulation by symbiont of host inflammatory response											GO:0052260		biological_process											owl:Class	
GO:0031897	biolink:NamedThing	Tic complex	The translocon of the inner envelope of chloroplasts, which facilitates the import of proteins across the chloroplast inner membrane.	tmpzr1t_l9r_go_relaxed.owl	chloroplast inner membrane translocase complex													cellular_component											owl:Class	
GO:0019339	biolink:NamedThing	parathion catabolic process	The chemical reactions and pathways resulting in the breakdown of parathion, a highly toxic organophosphate compound. Degradation of parathion by sunlight or liver enzymes can result in the formation of the active compound paraoxon which interferes with the nervous system through cholinesterase inhibition.	tmpzr1t_l9r_go_relaxed.owl	parathion degradation|parathion catabolism|parathion breakdown				MetaCyc:PARATHION-DEGRADATION-PWY									biological_process											owl:Class	
GO:0061170	biolink:NamedThing	negative regulation of hair follicle placode formation	Any process that decreases the rate, frequency, or extent of hair follicle placode formation, the developmental process in which a hair placode forms. An hair follicle placode is a thickening of the ectoderm that will give rise to the hair follicle bud.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-06-25T01:10:48Z					biological_process											owl:Class	
GO:1904559	biolink:NamedThing	cellular response to dextromethorphan	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dextromethorphan stimulus.	tmpzr1t_l9r_go_relaxed.owl								mr	2015-08-14T16:09:24Z					biological_process											owl:Class	
GO:0150139	biolink:NamedThing	positive regulation of interleukin-37 production	Any process that activates or increases the frequency, rate or extent of interleukin-37 production.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of interleukin-37 biosynthetic process							bc	2019-12-08T08:47:29Z					biological_process											owl:Class	
GO:1902664	biolink:NamedThing	positive regulation of peptidyl-L-cysteine S-palmitoylation	Any process that activates or increases the frequency, rate or extent of peptidyl-L-cysteine S-palmitoylation.	tmpzr1t_l9r_go_relaxed.owl	activation of peptidyl-S-palmitoyl-L-cysteine synthesis from peptidyl-cysteine|up-regulation of peptidyl-S-palmitoyl-L-cysteine synthesis from peptidyl-cysteine|activation of peptidyl-S-palmitoyl-L-cysteine formation from peptidyl-cysteine|up-regulation of peptidyl-S-palmitoyl-L-cysteine anabolism from peptidyl-cysteine|up regulation of peptidyl-cysteine S-palmitoylation|up-regulation of peptidyl-cysteine S-palmitoylation|positive regulation of peptidyl-S-palmitoyl-L-cysteine biosynthetic process from peptidyl-cysteine|positive regulation of peptidyl-S-palmitoyl-L-cysteine anabolism from peptidyl-cysteine|up regulation of peptidyl-S-palmitoyl-L-cysteine biosynthetic process from peptidyl-cysteine|upregulation of peptidyl-S-palmitoyl-L-cysteine formation from peptidyl-cysteine|activation of peptidyl-cysteine S-palmitoylation|up regulation of peptidyl-S-palmitoyl-L-cysteine synthesis from peptidyl-cysteine|activation of peptidyl-S-palmitoyl-L-cysteine biosynthetic process from peptidyl-cysteine|upregulation of peptidyl-S-palmitoyl-L-cysteine biosynthetic process from peptidyl-cysteine|up-regulation of peptidyl-S-palmitoyl-L-cysteine biosynthetic process from peptidyl-cysteine|positive regulation of peptidyl-cysteine S-palmitoylation|activation of peptidyl-S-palmitoyl-L-cysteine anabolism from peptidyl-cysteine|up regulation of peptidyl-S-palmitoyl-L-cysteine formation from peptidyl-cysteine|up-regulation of peptidyl-S-palmitoyl-L-cysteine formation from peptidyl-cysteine|upregulation of peptidyl-L-cysteine S-palmitoylation|upregulation of peptidyl-cysteine S-palmitoylation|up regulation of peptidyl-L-cysteine S-palmitoylation|positive regulation of peptidyl-S-palmitoyl-L-cysteine synthesis from peptidyl-cysteine|upregulation of peptidyl-S-palmitoyl-L-cysteine anabolism from peptidyl-cysteine|up-regulation of peptidyl-L-cysteine S-palmitoylation|up regulation of peptidyl-S-palmitoyl-L-cysteine anabolism from peptidyl-cysteine|positive regulation of peptidyl-S-palmitoyl-L-cysteine formation from peptidyl-cysteine|activation of peptidyl-L-cysteine S-palmitoylation|upregulation of peptidyl-S-palmitoyl-L-cysteine synthesis from peptidyl-cysteine							mm2	2014-01-29T11:33:28Z					biological_process											owl:Class	
GO:0003992	biolink:NamedThing	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity	Catalysis of the reaction: 2-oxoglutarate + N(2)-acetyl-L-ornithine = N-acetyl-L-glutamate 5-semialdehyde + L-glutamate.	tmpzr1t_l9r_go_relaxed.owl	N-acetylornithine-delta-transaminase activity|succinylornithine aminotransferase activity|N(2)-acetylornithine 5-transaminase activity|N-acetylornithine aminotransferase activity|ACOAT activity|N2-acetyl-L-ornithine:2-oxoglutarate aminotransferase activity|acetylornithine 5-aminotransferase activity|acetylornithine delta-transaminase activity|acetylornithine aminotransferase activity|acetylornithine transaminase activity|2-N-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity|N2-acetylornithine 5-transaminase activity|N2-acetylornithine 5-aminotransferase activity				EC:2.6.1.11|MetaCyc:ACETYLORNTRANSAM-RXN|KEGG_REACTION:R02283|RHEA:18049							GO:0047318		molecular_function											owl:Class	
GO:0010768	biolink:NamedThing	negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage	Any process that decreases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a UV damage stimulus.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0039663	biolink:NamedThing	membrane fusion involved in viral entry into host cell	Merging of the virion membrane and a host membrane (host plasma membrane or host organelle membrane) that is involved in the uptake of a virus into a host cell.	tmpzr1t_l9r_go_relaxed.owl	fusion of virus membrane with host membrane|viral entry into host cell via membrane fusion|fusion of virus membrane with host membrane during viral entry							bf	2013-08-29T10:15:11Z					biological_process											owl:Class	
GO:0046072	biolink:NamedThing	dTDP metabolic process	The chemical reactions and pathways involving dTDP, deoxyribosylthymine diphosphate.	tmpzr1t_l9r_go_relaxed.owl	dTDP metabolism													biological_process											owl:Class	
GO:0030912	biolink:NamedThing	response to deep water	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a deep water stimulus, being immersed in standing deep water throughout the life cycle.	tmpzr1t_l9r_go_relaxed.owl						Note that this term should not be confused with 'response to flooding ; GO:0009413'; which refers to immersion in water on a shorter time scale.								biological_process											owl:Class	
GO:0046326	biolink:NamedThing	positive regulation of glucose import	Any process that activates or increases the frequency, rate or extent of the import of the hexose monosaccharide glucose into a cell or organelle.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of glucose import|positive regulation of glucose uptake|stimulation of glucose import|activation of glucose import|up regulation of glucose import|upregulation of glucose import													biological_process											owl:Class	
GO:0046324	biolink:NamedThing	regulation of glucose import	Any process that modulates the frequency, rate or extent of the import of the hexose monosaccharide glucose into a cell or organelle.	tmpzr1t_l9r_go_relaxed.owl	regulation of glucose uptake													biological_process											owl:Class	
GO:1904040	biolink:NamedThing	positive regulation of iron export across plasma membrane	Any process that activates or increases the frequency, rate or extent of export of iron ions from inside of a cell, across the plasma membrane and into the extracellular region.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of ferrous iron export|positive regulation of ferrous iron export|up regulation of iron(2+) export|up regulation of ferrous iron export|positive regulation of iron(2+) export|upregulation of iron(2+) export|activation of ferrous iron export|upregulation of ferrous iron export|up-regulation of iron(2+) export|activation of iron(2+) export							kom	2015-03-16T15:36:49Z					biological_process											owl:Class	
GO:0061677	biolink:NamedThing	2-dehydro-3-deoxy-D-gluconate aldolase activity	Catalysis of the reaction: 2-dehydro-3-deoxy-D-gluconate <=> pyruvate + D-glyceraldehyde.	tmpzr1t_l9r_go_relaxed.owl	2-keto-3-deoxygluconate aldolase activity|KDG aldolase activity				MetaCyc:4.1.2.51-RXN|RHEA:35583|MetaCyc:DHDOGALDOL-RXN|EC:4.1.2.51			dph	2015-01-15T13:46:25Z			GO:0043725		molecular_function											owl:Class	
GO:0034516	biolink:NamedThing	response to vitamin B6	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin B6 stimulus. Vitamin B6 encompasses pyridoxal, pyridoxamine and pyridoxine and the active form, pyridoxal phosphate.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0051473	biolink:NamedThing	glucosylglycerol biosynthetic process	The chemical reactions and pathways resulting in the formation of glucosylglycerol, alpha-D-glucopyranosyl-alpha-(1,2)-glycerol.	tmpzr1t_l9r_go_relaxed.owl	glucosylglycerol formation|glucosylglycerol synthesis|glucosylglycerol biosynthesis|glucosylglycerol anabolism													biological_process											owl:Class	
GO:1904242	biolink:NamedThing	regulation of pancreatic trypsinogen secretion	Any process that modulates the frequency, rate or extent of pancreatic trypsinogen secretion.	tmpzr1t_l9r_go_relaxed.owl	regulation of pancreatic trypsinogen release							sl	2015-05-18T19:49:20Z					biological_process											owl:Class	
GO:0019153	biolink:NamedThing	protein-disulfide reductase (glutathione) activity	Catalysis of the reaction: 2 glutathione + protein-disulfide = oxidized glutathione + protein-dithiol.	tmpzr1t_l9r_go_relaxed.owl	glutathione--insulin transhydrogenase activity|glutathione:protein-disulfide oxidoreductase activity|GSH-insulin transhydrogenase activity|protein-disulphide reductase (glutathione) activity|thiol-protein disulphide oxidoreductase activity|protein disulfide transhydrogenase activity|protein-disulfide isomerase/oxidoreductase activity|reductase, protein disulfide (glutathione)|glutathione-protein disulfide oxidoreductase activity|glutaredoxin reductase|insulin reductase activity|protein disulfide reductase (glutathione)|glutathione-insulin transhydrogenase activity|thiol:protein-disulfide oxidoreductase activity|protein-disulfide interchange enzyme	https://github.com/geneontology/go-ontology/issues/21148			MetaCyc:PRODISULFREDUCT-RXN|EC:1.8.4.2|RHEA:21064									molecular_function											owl:Class	
GO:0016772	biolink:NamedThing	transferase activity, transferring phosphorus-containing groups	Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to another (acceptor).	tmpzr1t_l9r_go_relaxed.owl					EC:2.7.-.-	Note that this term encompasses all kinase activities, as well as activities that transfer other phosphorus-containing groups such as diphosphate or nucleotides.								molecular_function											owl:Class	
GO:0002212	biolink:NamedThing	behavioral defense response to nematode	A behavioral response seeking to protect an organism from an a perceived external threat from a nematode or nematodes to that organism.	tmpzr1t_l9r_go_relaxed.owl	behavioural defense response to nematode													biological_process											owl:Class	
GO:0002215	biolink:NamedThing	defense response to nematode	A response to protect an organism from a directly detected or perceived external threat from a nematode or nematodes, which results in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack.	tmpzr1t_l9r_go_relaxed.owl	physiological defense response to nematode											GO:0002216		biological_process											owl:Class	
GO:0046466	biolink:NamedThing	membrane lipid catabolic process	The chemical reactions and pathways resulting in the breakdown of membrane lipids, any lipid found in or associated with a biological membrane.	tmpzr1t_l9r_go_relaxed.owl	membrane lipid catabolism|membrane lipid peroxidation|membrane lipid degradation|membrane lipid breakdown													biological_process											owl:Class	
GO:0001810	biolink:NamedThing	regulation of type I hypersensitivity	Any process that modulates the frequency, rate, or extent of type I hypersensitivity, a type of inflammatory response.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0004746	biolink:NamedThing	riboflavin synthase activity	Catalysis of the reaction: 2 6,7-dimethyl-8-(1-D-ribityl)lumazine + H(+) = 5-amino-6-(D-ribitylamino)uracil + riboflavin.	tmpzr1t_l9r_go_relaxed.owl	heavy riboflavin synthase|riboflavine synthase activity|lumazine synthase activity|light riboflavin synthase|6,7-dimethyl-8-(1-D-ribityl)lumazine:6,7-dimethyl-8-(1-D-ribityl)lumazine 2,3-butanediyltransferase activity|riboflavine synthetase activity|vitamin B2 synthase activity|riboflavin synthetase activity				EC:2.5.1.9|KEGG_REACTION:R00066|MetaCyc:RIBOFLAVIN-SYN-RXN|RHEA:20772									molecular_function											owl:Class	
GO:0046232	biolink:NamedThing	carbazole catabolic process	The chemical reactions and pathways resulting in the breakdown of carbazole, a heterocyclic aromatic compound containing a dibenzopyrrole system that is produced during coal gasification and is present in cigarette smoke. Coal tar produced at high temperature contains an average of 1.5% carbazole. It is used widely in synthesis of dyes, pharmaceuticals, and plastics and is a suspected carcinogen.	tmpzr1t_l9r_go_relaxed.owl	carbazole breakdown|carbazole catabolism|carbazole degradation													biological_process											owl:Class	
GO:0006983	biolink:NamedThing	ER overload response	The series of molecular signals generated by the accumulation of normal or misfolded proteins in the endoplasmic reticulum and leading to activation of transcription by NF-kappaB.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of NF-kappaB transcription factor activity by ER overload response|endoplasmic reticulum overload response|EOR|EOR-mediated NF-kappaB activation|ER-overload response|EOR-mediated activation of NF-kappaB|positive regulation of NF-kappaB transcription factor activity by EOR											GO:0006985		biological_process											owl:Class	
GO:0006984	biolink:NamedThing	ER-nucleus signaling pathway	Any series of molecular signals that conveys information from the endoplasmic reticulum to the nucleus, usually resulting in a change in transcriptional regulation.	tmpzr1t_l9r_go_relaxed.owl	endoplasmic reticulum-nuclear signaling pathway|endoplasmic reticulum to nucleus signaling pathway|ER to nucleus signaling pathway|ER-nuclear signalling pathway|ER to nucleus signalling pathway|ER-nuclear signaling pathway													biological_process											owl:Class	
GO:0010135	biolink:NamedThing	ureide metabolic process	The chemical reactions and pathways involving ureide, allantoin and allantoate, which are the organic forms of nitrogen in nitrogen fixing and transporting plants.	tmpzr1t_l9r_go_relaxed.owl	ureide metabolism													biological_process											owl:Class	
GO:1900836	biolink:NamedThing	positive regulation of emericellin biosynthetic process	Any process that activates or increases the frequency, rate or extent of emericellin biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl								di	2012-06-07T09:32:31Z					biological_process											owl:Class	
GO:0045575	biolink:NamedThing	basophil activation	The change in morphology and behavior of a basophil resulting from exposure to a cytokine, chemokine, soluble factor, or to (at least in mammals) an antigen which the basophil has specifically bound via IgE bound to Fc-epsilonRI receptors.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Basophil_activation									biological_process											owl:Class	
GO:0036230	biolink:NamedThing	granulocyte activation	The change in morphology and behavior of a granulocyte resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor.	tmpzr1t_l9r_go_relaxed.owl								bf	2012-05-11T10:57:48Z					biological_process											owl:Class	
GO:0007341	biolink:NamedThing	penetration of zona pellucida	The infiltration by sperm of the zona pellucida to reach the oocyte. The process involves digestive enzymes from a modified lysosome called the acrosome, situated at the head of the sperm.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0062136	biolink:NamedThing	low-density lipoprotein receptor complex	A plasma membrane protein complex capable of low-density lipoprotein particle receptor activity. It may also bind xenobiotic toxins and deliver them into the cell via endocytosis. While most substrates get degraded via the endosome the receptor is recycled to the plasma membrane. It may also act as a transducer of intracellular signal pathways and often acts in corporation with other cell-surface receptors.	tmpzr1t_l9r_go_relaxed.owl	LDL receptor complex|LDLR complex|low-density lipoprotein particle receptor complex							dph	2019-07-02T13:41:28Z					cellular_component											owl:Class	
GO:0072107	biolink:NamedThing	positive regulation of ureteric bud formation	Any process that increases the rate or extent of the developmental process pertaining to the initial formation of the ureteric bud from the Wolffian duct.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-02-12T02:37:28Z					biological_process											owl:Class	
GO:0120235	biolink:NamedThing	regulation of posttranslational protein targeting to membrane, translocation	Any process that modulates the frequency, rate or extent of posttranslational protein translocation through the ER membrane.	tmpzr1t_l9r_go_relaxed.owl	regulation of SRP-independent endoplasmic reticulum protein-membrane targeting, translocation|regulation of posttranslational endoplasmic reticulum membrane protein translocation|regulation of N-terminal signal peptide-independent translocation into the ER	https://github.com/geneontology/go-ontology/issues/19791						krc	2020-08-03T16:46:15Z					biological_process											owl:Class	
GO:0102121	biolink:NamedThing	ceramidase activity	Catalysis of the reaction: H2O + a ceramide = a sphingoid base + a fatty acid.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-11375|EC:3.5.1.23									molecular_function											owl:Class	
GO:0102964	biolink:NamedThing	S-adenosyl-L-methionine:(S)-corytuberine-N-methyltransferase activity	Catalysis of the reaction: (S)-corytuberine + S-adenosyl-L-methionine  <=> H+ + magnoflorine + S-adenosyl-L-homocysteine.	tmpzr1t_l9r_go_relaxed.owl					RHEA:51524|MetaCyc:RXN-9315									molecular_function											owl:Class	
GO:0120284	biolink:NamedThing	tryptophan binding	Binding to 2-amino-3-(1H-indol-3-yl)propanoic acid.	tmpzr1t_l9r_go_relaxed.owl	Trp binding	https://github.com/geneontology/go-ontology/issues/20181						krc	2020-11-18T01:04:19Z					molecular_function											owl:Class	
GO:0043378	biolink:NamedThing	positive regulation of CD8-positive, alpha-beta T cell differentiation	Any process that activates or increases the frequency, rate or extent of CD8-positive, alpha-beta T cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of CD8-positive T-lymphocyte differentiation|positive regulation of CD8-positive, alpha beta T-cell differentiation|positive regulation of CD8-positive, alpha beta T-lymphocyte differentiation|positive regulation of CD8-positive T lymphocyte differentiation|stimulation of CD8-positive, alpha-beta T cell differentiation|up-regulation of CD8-positive, alpha-beta T cell differentiation|upregulation of CD8-positive, alpha-beta T cell differentiation|up regulation of CD8-positive, alpha-beta T cell differentiation|positive regulation of CD8-positive T-cell differentiation|activation of CD8-positive, alpha-beta T cell differentiation|positive regulation of CD8-positive, alpha-beta T cell development|positive regulation of CD8-positive, alpha beta T lymphocyte differentiation					Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.								biological_process											owl:Class	
GO:1905305	biolink:NamedThing	negative regulation of cardiac myofibril assembly	Any process that stops, prevents or reduces the frequency, rate or extent of cardiac myofibril assembly.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of cardiac myofibril assembly|down regulation of cardiac myofibril assembly|downregulation of cardiac myofibril morphogenesis|down-regulation of cardiac myofibril morphogenesis|negative regulation of cardiac myofibril development|down-regulation of cardiac myofibril development|inhibition of cardiac myofibril assembly|downregulation of cardiac myofibril development|down-regulation of heart myofibril assembly|down regulation of heart myofibril assembly|negative regulation of heart myofibril assembly|inhibition of cardiac myofibril development|down regulation of cardiac myofibril development|inhibition of cardiac myofibril morphogenesis|downregulation of cardiac myofibril assembly|downregulation of heart myofibril assembly|negative regulation of cardiac myofibril morphogenesis|inhibition of heart myofibril assembly|down regulation of cardiac myofibril morphogenesis							rl	2016-07-06T10:01:58Z					biological_process											owl:Class	
GO:1905304	biolink:NamedThing	regulation of cardiac myofibril assembly	Any process that modulates the frequency, rate or extent of cardiac myofibril assembly.	tmpzr1t_l9r_go_relaxed.owl	regulation of heart myofibril assembly|regulation of cardiac myofibril morphogenesis|regulation of cardiac myofibril development							rl	2016-07-06T10:01:49Z					biological_process											owl:Class	
GO:0002060	biolink:NamedThing	purine nucleobase binding	Binding to a purine nucleobase, an organic nitrogenous base with a purine skeleton.	tmpzr1t_l9r_go_relaxed.owl	purine base binding|purine binding													molecular_function											owl:Class	
GO:0002054	biolink:NamedThing	nucleobase binding	Binding to a nucleobase, any of a class of pyrmidines or purines, organic nitrogenous bases.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0033342	biolink:NamedThing	negative regulation of collagen binding	Any process that stops, prevents, or reduces the frequency, rate or extent of collagen binding.	tmpzr1t_l9r_go_relaxed.owl	inhibition of collagen binding|down regulation of collagen binding|downregulation of collagen binding|down-regulation of collagen binding													biological_process											owl:Class	
GO:0070908	biolink:NamedThing	tyrosine:tyramine antiporter activity	Catalysis of the reaction: tyrosine(out) + tyramine(in) = tyrosine(in) + tyramine(out).	tmpzr1t_l9r_go_relaxed.owl	tyrosine-tyramine antiporter activity|tyrosine/tyramine antiporter activity							mah	2009-09-04T03:49:45Z					molecular_function											owl:Class	
GO:0000453	biolink:NamedThing	enzyme-directed rRNA 2'-O-methylation	The addition of methyl groups to the 2'-oxygen atom of nucleotide residues in an rRNA molecule during ribosome biogenesis where the methylase specifies the site that becomes methylated without using a guide RNA.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0000451	biolink:NamedThing	rRNA 2'-O-methylation	The addition of a methyl group to the 2'-oxygen atom of a nucleotide residue in an rRNA molecule during ribosome biogenesis.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0016885	biolink:NamedThing	ligase activity, forming carbon-carbon bonds	Catalysis of the joining of two molecules via a carbon-carbon bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.	tmpzr1t_l9r_go_relaxed.owl					EC:6.4.-.-									molecular_function											owl:Class	
GO:0060405	biolink:NamedThing	regulation of penile erection	Any process that modulates the rate, frequency or extent of penile erection. Penile erection is the hardening, enlarging and rising of the penis which often occurs in the sexually aroused male and enables sexual intercourse. Achieved by increased inflow of blood into the vessels of erectile tissue, and decreased outflow.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0051516	biolink:NamedThing	regulation of bipolar cell growth	Any process that modulates the frequency, rate or extent of bipolar cell growth, polarized growth from both ends of a cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0033360	biolink:NamedThing	lysine biosynthetic process via diaminopimelate and L-2-acetamido-6-oxoheptanedioate	The chemical reactions and pathways resulting in the formation of lysine, via the intermediates diaminopimelate and L-2-acetamido-6-oxoheptanedioate; in this pathway tetrahydrodipicolinate is converted to meso-diaminopimelate in four enzymatic steps.	tmpzr1t_l9r_go_relaxed.owl	lysine biosynthetic process via diaminopimelic acid and L-2-acetamido-6-oxoheptanedioate|lysine biosynthesis via diaminopimelic acid and L-2-acetamido-6-oxoheptanedioate|lysine anabolism via diaminopimelate and L-2-acetamido-6-oxoheptanedioate|lysine synthesis via diaminopimelate and L-2-acetamido-6-oxoheptanedioate|lysine formation via diaminopimelate and L-2-acetamido-6-oxoheptanedioate				MetaCyc:PWY-2941									biological_process											owl:Class	
GO:0032868	biolink:NamedThing	response to insulin	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin stimulus. Insulin is a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms.	tmpzr1t_l9r_go_relaxed.owl	response to insulin stimulus													biological_process											owl:Class	
GO:0043434	biolink:NamedThing	response to peptide hormone	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide hormone stimulus. A peptide hormone is any of a class of peptides that are secreted into the blood stream and have endocrine functions in living animals.	tmpzr1t_l9r_go_relaxed.owl	response to peptide hormone stimulus|response to polypeptide hormone stimulus													biological_process											owl:Class	
GO:1990554	biolink:NamedThing	mitochondrial 3'-phospho-5'-adenylyl sulfate transmembrane transport	The process in which 3'-phospho-5'-adenylyl sulfate is transported across a mitochondrial membrane, into or out of the mitochondrion.	tmpzr1t_l9r_go_relaxed.owl								vw	2014-11-19T12:39:22Z					biological_process											owl:Class	
GO:1990898	biolink:NamedThing	meiotic DNA double-strand break clipping	The process by which SPO11/Rec12-oligonucleotide complexes are removed from 5' DNA double-strand breaks induced during meiosis. Proteins involved in this process include the MRX/MRN complex and Sae2/Ctp1/RBBP8(CtIP).	tmpzr1t_l9r_go_relaxed.owl								al	2015-11-10T17:12:27Z					biological_process											owl:Class	
GO:0018809	biolink:NamedThing	E-phenylitaconyl-CoA hydratase activity	Catalysis of the reaction: E-phenylitaconyl-CoA + H2O = (hydroxymethylphenyl)succinyl-CoA.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0331									molecular_function											owl:Class	
GO:0009092	biolink:NamedThing	homoserine metabolic process	The chemical reactions and pathways involving homoserine, alpha-amino-gamma-hydroxybutyric acid, an intermediate in the biosynthesis of cystathionine, threonine and methionine.	tmpzr1t_l9r_go_relaxed.owl	homoserine metabolism													biological_process											owl:Class	
GO:0015814	biolink:NamedThing	p-aminobenzoyl-glutamate transport	The directed movement of p-aminobenzoyl-glutamate, the anion of p-aminobenzoyl-glutamic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0045628	biolink:NamedThing	regulation of T-helper 2 cell differentiation	Any process that modulates the frequency, rate or extent of T-helper 2 cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	regulation of T-helper 2 cell development					Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.								biological_process											owl:Class	
GO:0046113	biolink:NamedThing	nucleobase catabolic process	The chemical reactions and pathways resulting in the breakdown of a nucleobase, a nitrogenous base that is a constituent of a nucleic acid.	tmpzr1t_l9r_go_relaxed.owl	nucleobase breakdown|nucleobase catabolism|nucleobase degradation													biological_process											owl:Class	
GO:0016516	biolink:NamedThing	interleukin-4 receptor complex	A protein complex that binds interleukin-4 (IL-4) and consists of an alpha chain that binds IL-4 with high affinity and a gamma common chain that also forms part of the interleukin-2 receptor.	tmpzr1t_l9r_go_relaxed.owl	IL-4 receptor complex													cellular_component											owl:Class	
GO:0002867	biolink:NamedThing	regulation of B cell deletion	Any process that modulates the frequency, rate, or extent of B cell deletion.	tmpzr1t_l9r_go_relaxed.owl	regulation of B-lymphocyte deletion|regulation of B lymphocyte deletion|regulation of B-cell deletion													biological_process											owl:Class	
GO:0001720	biolink:NamedThing	conversion of lysyl-tRNA to pyrrolysyl-tRNA	The modification process that results in the conversion of lysine, carried by a specialized lysine-accepting tRNA (possessing a CUA anticodon), to pyrrolysine (a lysine with an amide linkage to a (4R,5R)-4-substituted pyrroline-5-carboxylate).	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0035854	biolink:NamedThing	eosinophil fate commitment	The process in which the developmental fate of a cell becomes restricted such that it will develop into a eosinophil cell. A eosinophil is any of the immature or mature forms of a granular leukocyte with a nucleus that usually has two lobes connected by one or more slender threads of chromatin, and cytoplasm containing coarse, round granules that are uniform in size and which can be stained by the dye eosin.	tmpzr1t_l9r_go_relaxed.owl	eosinophil cell fate commitment							bf	2011-05-13T01:23:28Z					biological_process											owl:Class	
GO:0003138	biolink:NamedThing	primary heart field specification	The process that results in the delineation of a specific region of the lateral mesoderm into the area which will form the primary beating heart tube. In mammals the primary heart field gives rise to the left ventricle.	tmpzr1t_l9r_go_relaxed.owl	first heart field specification|FHS specification							tb	2009-09-22T03:47:24Z					biological_process											owl:Class	
GO:1901452	biolink:NamedThing	negative regulation of response to benzene	Any process that stops, prevents or reduces the frequency, rate or extent of response to benzene.	tmpzr1t_l9r_go_relaxed.owl	inhibition of response to benzene|downregulation of response to benzene|down-regulation of response to benzene|down regulation of response to benzene							tt	2012-10-02T14:20:23Z					biological_process											owl:Class	
GO:1901451	biolink:NamedThing	regulation of response to benzene	Any process that modulates the frequency, rate or extent of response to benzene.	tmpzr1t_l9r_go_relaxed.owl								tt	2012-10-02T14:19:10Z					biological_process											owl:Class	
GO:0099134	biolink:NamedThing	chimeric sorocarp development	Development of a sorocarp formed by aggregation of cells with different genotypes.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0030587	biolink:NamedThing	sorocarp development	The process whose specific outcome is the progression of the sorocarp over time, from its formation to the mature structure. The process begins with the aggregation of individual cells and ends with the mature sorocarp. The sorocarp is a structure containing a spore-bearing sorus that sits on top of a stalk. An example of this process is found in Dictyostelium discoideum.	tmpzr1t_l9r_go_relaxed.owl	sorocarp biosynthesis|fruiting body development|fruiting body formation|sorocarp formation													biological_process											owl:Class	
GO:0048358	biolink:NamedThing	mucilage pectin biosynthetic process	The chemical reactions and pathways resulting in the formation of the pectin component of mucilage.	tmpzr1t_l9r_go_relaxed.owl	mucilage pectin biosynthesis|mucilage pectin synthesis|mucilage pectin formation|mucilage pectin anabolism													biological_process											owl:Class	
GO:0048363	biolink:NamedThing	mucilage pectin metabolic process	The chemical reactions and pathways involving the pectin component of mucilage.	tmpzr1t_l9r_go_relaxed.owl	mucilage pectin metabolism													biological_process											owl:Class	
GO:0004787	biolink:NamedThing	thiamine-diphosphatase activity	Catalysis of the reaction: TPP + H2O = TMP + phosphate.	tmpzr1t_l9r_go_relaxed.owl	thiamin-pyrophosphatase activity|thiaminpyrophosphatase activity|thiamine pyrophosphatase activity|TPPase activity|thiamin pyrophosphatase activity				RHEA:27998									molecular_function											owl:Class	
GO:0051326	biolink:NamedThing	telophase	The cell cycle phase which follows anaphase during M phase of mitosis and meiosis and during which the chromosomes arrive at the poles of the cell and the division of the cytoplasm starts.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Telophase	note that this term should not be used for direct annotation. if you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic s-phase). to capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).								biological_process											owl:Class	
GO:0106130	biolink:NamedThing	purine phosphoribosyltransferase activity	Catalysis of the reaction: RMP + diphosphate = R + 5-phospho-alpha-D-ribose 1-diphosphate.	tmpzr1t_l9r_go_relaxed.owl								hjd	2018-06-14T17:38:53Z					molecular_function											owl:Class	
GO:0032644	biolink:NamedThing	regulation of fractalkine production	Any process that modulates the frequency, rate, or extent of fractalkine production.	tmpzr1t_l9r_go_relaxed.owl	regulation of CX3CL1 production|regulation of fractalkine biosynthetic process|regulation of CX3CL1 biosynthesis	https://github.com/geneontology/go-ontology/issues/19254										GO:0050752		biological_process											owl:Class	
GO:0052317	biolink:NamedThing	camalexin metabolic process	The chemical reactions and pathways involving camalexin, an indole phytoalexin.	tmpzr1t_l9r_go_relaxed.owl	camalexin metabolism													biological_process											owl:Class	
GO:0003266	biolink:NamedThing	regulation of secondary heart field cardioblast proliferation	Any process that modulates the frequency, rate or extent of cardioblast proliferation in the second heart field. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating. The secondary heart field is the region of the heart that will form the majority of the mesodermal component of the right ventricle, the arterial pole (outflow tract) and the venous pole (inflow tract).	tmpzr1t_l9r_go_relaxed.owl	regulation of second heart field cardioblast proliferation|regulation of SHF cardioblast proliferation							dph	2009-10-15T02:26:15Z					biological_process											owl:Class	
GO:0006023	biolink:NamedThing	aminoglycan biosynthetic process	The chemical reactions and pathways resulting in the formation of aminoglycans, any polymer containing amino groups that consists of more than about 10 monosaccharide residues joined to each other by glycosidic linkages.	tmpzr1t_l9r_go_relaxed.owl	aminoglycan biosynthesis|aminoglycan synthesis|aminoglycan anabolism|aminoglycan formation													biological_process											owl:Class	
GO:2001253	biolink:NamedThing	regulation of histone H3-K36 trimethylation	Any process that modulates the frequency, rate or extent of histone H3-K36 trimethylation.	tmpzr1t_l9r_go_relaxed.owl								pr	2011-12-06T07:38:09Z					biological_process											owl:Class	
GO:1901673	biolink:NamedThing	regulation of mitotic spindle assembly	Any process that modulates the frequency, rate or extent of mitotic spindle assembly.	tmpzr1t_l9r_go_relaxed.owl	regulation of spindle assembly involved in mitosis							al	2012-11-22T09:50:00Z					biological_process											owl:Class	
GO:0035901	biolink:NamedThing	cellular response to isolation stress	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lack of contact with other members of the same species.	tmpzr1t_l9r_go_relaxed.owl	cellular response to social isolation							bf	2011-06-22T09:43:34Z					biological_process											owl:Class	
GO:0046535	biolink:NamedThing	detection of chemical stimulus involved in sensory perception of umami taste	The series of events required for a umami taste stimulus to be received and converted to a molecular signal. Umami taste is the savory taste of meats and other foods that are rich in glutamates.	tmpzr1t_l9r_go_relaxed.owl	sensory detection of chemical stimulus during perception of umami taste|umami taste detection|sensory transduction of chemical stimulus during perception of umami taste|perception of umami taste, detection of chemical stimulus|perception of umami taste, sensory transduction of chemical stimulus|sensory detection of umami taste|sensory transduction of umami taste													biological_process											owl:Class	
GO:0070621	biolink:NamedThing	EGFR-Shc-Grb2-Sos complex	A protein complex that contains the epidermal growth factor receptor (EGFR), Grb2, the adaptor protein SHC and the guanine nucleotide exchange factor Sos (or an ortholog thereof, such as mSos1), and is involved in linking EGFR activation to the p21-Ras pathway.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-04-29T04:38:10Z					cellular_component											owl:Class	
GO:0042343	biolink:NamedThing	indole glucosinolate metabolic process	The chemical reactions and pathways resulting in the formation of indole glucosinolates. Glucosinolates are sulfur-containing compounds that have a common structure linked to an R group derived from tryptophan; indoles are biologically active substances based on 2,3-benzopyrrole, formed during the catabolism of tryptophan.	tmpzr1t_l9r_go_relaxed.owl	indole glucosinolate metabolism													biological_process											owl:Class	
GO:0045676	biolink:NamedThing	regulation of R7 cell differentiation	Any process that modulates the frequency, rate or extent of R7 differentiation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0032631	biolink:NamedThing	interleukin-27 production	The appearance of interleukin-27 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	tmpzr1t_l9r_go_relaxed.owl	interleukin-27 synthesis|interleukin-27 secretion|IL-27 production|interleukin-27 formation|interleukin-27 biosynthetic process											GO:0045527|GO:0072625		biological_process											owl:Class	
GO:0099101	biolink:NamedThing	G-protein gated potassium channel activity	A potassium channel activity that is gated by binding of a G-protein beta-gamma dimer.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1904325	biolink:NamedThing	positive regulation of inhibitory G protein-coupled receptor phosphorylation	Any process that activates or increases the frequency, rate or extent of inhibitory G protein-coupled receptor phosphorylation.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of inhibitory G-protein coupled receptor phosphorylation|positive regulation of inhibitory G-protein coupled receptor phosphorylation|activation of inhibitory G-protein coupled receptor phosphorylation|up regulation of inhibitory G-protein coupled receptor phosphorylation|upregulation of inhibitory G-protein coupled receptor phosphorylation							sl	2015-06-10T19:46:50Z					biological_process											owl:Class	
GO:1904680	biolink:NamedThing	peptide transmembrane transporter activity	Enables the transfer of a peptide from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	peptide transporter activity|peptide uptake permease activity				Reactome:R-HSA-1500817			tb	2015-09-22T18:50:41Z			GO:0015637|GO:0015197		molecular_function											owl:Class	
GO:0019729	biolink:NamedThing	peptide cross-linking via 2-imino-glutaminyl-5-imidazolinone glycine	The formation of the fluorescent protein FP583 chromophore cross-link from the alpha-carboxyl carbon of residue n, a glutamine, to the alpha-amino nitrogen of residue n+2, a glycine, and a dehydration to form a double bond to the alpha-amino nitrogen of residue n+1. This cross-linking is coupled with a dehydrogenation of residue n+1 to form a double bond between the alpha and beta carbons.	tmpzr1t_l9r_go_relaxed.owl	biosynthesis of protein-protein cross-link via 2-imino-glutaminyl-5-imidazolinone glycine|biosynthetic process of protein-protein cross-link via 2-imino-glutaminyl-5-imidazolinone glycine				RESID:AA0189	See also the biological process term 'peptidyl-tyrosine dehydrogenation ; GO:0018251'.								biological_process											owl:Class	
GO:0098596	biolink:NamedThing	imitative learning	Learning in which new behaviors are acquired through imitation.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Imitative_learning|Wikipedia:Observational_learning#Observational_learning_compared_to_imitation			dos	2014-04-10T11:00:39Z					biological_process											owl:Class	
GO:0098597	biolink:NamedThing	observational learning	Learning that occurs through observing the behavior of others.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Observational_learning	Observation here is used in a broad sense to include perception of the behavior of others via any form or combination of forms of sensory perception (visual, auditory etc). Observational learning is broader than imitative learning in that it does not require a duplication of the behavior exhibited by the model.		dos	2014-04-10T11:07:10Z					biological_process											owl:Class	
GO:0140516	biolink:NamedThing	mitotic nuclear pore complex disassembly	The mitotic cell cycle process in which the controlled breakdown of the nuclear pores occurs during open or closed mitosis.	tmpzr1t_l9r_go_relaxed.owl	nuclear pore complex disassembly during mitosis	https://github.com/geneontology/go-ontology/issues/19947						pg	2020-09-09T15:29:01Z					biological_process											owl:Class	
GO:0070684	biolink:NamedThing	seminal clot liquefaction	The reproductive process in which coagulated semen becomes liquid following ejaculation, allowing the progressive release of motile spermatozoa.	tmpzr1t_l9r_go_relaxed.owl	semen liquefaction							mah	2009-06-02T04:33:54Z					biological_process											owl:Class	
GO:0070871	biolink:NamedThing	cell wall organization involved in conjugation with cellular fusion	A process of cell wall organization that contributes to conjugation with cellular fusion.	tmpzr1t_l9r_go_relaxed.owl	cell wall organisation involved in conjugation with cellular fusion							mah	2009-08-20T02:23:19Z					biological_process											owl:Class	
GO:0071555	biolink:NamedThing	cell wall organization	A process that results in the assembly, arrangement of constituent parts, or disassembly of the cell wall, the rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells, maintaining their shape and protecting them from osmotic lysis.	tmpzr1t_l9r_go_relaxed.owl	cell wall organisation in other organism|cellular cell wall organization|cell wall organization at cellular level|cell wall organisation|cellular cell wall organisation|cell wall organization and biogenesis|cell wall organization in other organism							mah	2010-01-13T03:33:07Z			GO:0044234|GO:0007047		biological_process											owl:Class	
GO:0062185	biolink:NamedThing	secalciferol 1-monooxygenase activity	Catalysis of the reaction:2 H(+) + O2 + 2 reduced [adrenodoxin] + secalciferol = calcitetrol + H2O + 2 oxidized [adrenodoxin].	tmpzr1t_l9r_go_relaxed.owl					RHEA:49064			dph	2019-11-26T18:46:18Z					molecular_function											owl:Class	
GO:1900355	biolink:NamedThing	negative regulation of methanofuran metabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of methanofuran metabolic process.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of methanofuran metabolism|down regulation of methanofuran metabolism|down regulation of methanofuran metabolic process|down-regulation of methanofuran metabolic process|negative regulation of methanofuran metabolism|downregulation of methanofuran metabolic process|downregulation of methanofuran metabolism|inhibition of methanofuran metabolic process|inhibition of methanofuran metabolism							tt	2012-04-06T02:15:53Z					biological_process											owl:Class	
GO:0044162	biolink:NamedThing	host cell cytoplasmic vesicle membrane	The lipid bilayer surrounding a host cell cytoplasmic vesicle.	tmpzr1t_l9r_go_relaxed.owl								jl	2009-08-11T04:24:02Z					cellular_component											owl:Class	
GO:0018774	biolink:NamedThing	2,6-dioxo-6-phenylhexa-3-enoate hydrolase activity	Catalysis of the reaction: 2,6-dioxo-6-phenylhexa-3-enoate + H2O = benzoate + 2-oxopent-4-enoate.	tmpzr1t_l9r_go_relaxed.owl	HOHPDA hydrolase activity|2,6-dioxo-6-phenylhexa-3-enoate benzoylhydrolase activity|2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase activity				MetaCyc:3.7.1.8-RXN|RHEA:17161|EC:3.7.1.8|UM-BBD_enzymeID:e0033									molecular_function											owl:Class	
GO:0035365	biolink:NamedThing	regulation of thymine transport	Any process that modulates the frequency, rate or extent of the directed movement of thymine, 5-methyluracil, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	regulation of 5-methyluracil transport							bf	2010-03-11T10:22:54Z					biological_process											owl:Class	
GO:0075203	biolink:NamedThing	positive regulation of penetration hypha formation	Any process that activates, maintains or increases the frequency, rate or extent of symbiont penetration hypha formation for entry into host. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of symbiont penetration hypha formation for entry into host	https://github.com/geneontology/go-ontology/issues/21121				Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products from the symbiont involved in this process.								biological_process											owl:Class	
GO:0009647	biolink:NamedThing	skotomorphogenesis	The control of plant growth, development, and differentiation in response to growth in darkness.	tmpzr1t_l9r_go_relaxed.owl	etiolation													biological_process											owl:Class	
GO:0071683	biolink:NamedThing	sensory dendrite	A dendrite that is found on a sensory neuron, and directly transduces a sensory signal from the sensory neuron to another neuron.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-02-19T04:17:05Z					cellular_component											owl:Class	
GO:0071099	biolink:NamedThing	alphaV-beta6 integrin-TGFbeta-3 complex	A protein complex that consists of an alphaV-beta6 integrin complex bound to transforming growth factor beta-3 (TGFbeta-3).	tmpzr1t_l9r_go_relaxed.owl	ITGAV-ITGB6-TFGB3 complex							mah	2009-11-06T04:52:27Z					cellular_component											owl:Class	
GO:0010119	biolink:NamedThing	regulation of stomatal movement	Any process that modulates the frequency, rate or extent of stomatal movement.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0098765	biolink:NamedThing	meiosis II cell cycle phase	A meiotic cell cycle phase that occurs after meiosis I (the first meiotic nuclear division).	tmpzr1t_l9r_go_relaxed.owl						This term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation should be to 'regulation of x/y phase transition' or to a process which occurs during the reported phase (e.g. mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).								biological_process											owl:Class	
GO:0098762	biolink:NamedThing	meiotic cell cycle phase	One of the distinct periods or stages into which the meiotic cell cycle is divided. Each phase is characterized by the occurrence of specific biochemical and morphological events.	tmpzr1t_l9r_go_relaxed.owl						This term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation should be to 'regulation of x/y phase transition' or to a process which occurs during the reported phase (e.g. mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).								biological_process											owl:Class	
GO:0034430	biolink:NamedThing	monolayer-surrounded lipid storage body outer lipid monolayer	The single layer of phopholipids surrounding a lipid storage body.	tmpzr1t_l9r_go_relaxed.owl	oil body outer lipid monolayer|lipid droplet outer lipid monolayer|spherosome outer lipid monolayer|lipid storage body surface lipid monolayer|oleosome outer lipid monolayer													cellular_component											owl:Class	
GO:0034646	biolink:NamedThing	organelle-enclosing lipid monolayer	A lipid monolayer that surrounds and encloses an organelle.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:2000369	biolink:NamedThing	regulation of clathrin-dependent endocytosis	Any process that modulates the frequency, rate or extent of clathrin-mediated endocytosis.	tmpzr1t_l9r_go_relaxed.owl	regulation of clathrin-mediated endocytosis|regulation of clathrin coated pit-dependent endocytosis							mah	2011-02-09T12:36:18Z					biological_process											owl:Class	
GO:0018920	biolink:NamedThing	glyphosate metabolic process	The chemical reactions and pathways involving glyphosate, a broad-spectrum herbicide also known by the trade name Roundup. It is a member of a broad class of compounds known as phosphonic acids, which contain a direct carbon-to-phosphorus (C-P) bond.	tmpzr1t_l9r_go_relaxed.owl	Roundup metabolism|glyphosate metabolism|Roundup metabolic process				UM-BBD_pathwayID:gly									biological_process											owl:Class	
GO:0043428	biolink:NamedThing	2-heptaprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity	Catalysis of the reaction: 2-heptaprenyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-methionine = 2-heptaprenyl-3-methyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-homocysteine.	tmpzr1t_l9r_go_relaxed.owl	2-heptaprenyl-6-methoxy-1,4-benzoquinone methylase activity				RHEA:44756|MetaCyc:RXN-9227	Note that the polyprenyl sidechain substrate for these methyltransferases varies in length between species, for example, 6 units in S. cerevisiae, 8 units in E. coli and 10 units in G. suboxidans. Where the length of the substrate polyprenyl chain is unknown, the term '2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity ; GO:0008425' should be used.								molecular_function											owl:Class	
GO:1990297	biolink:NamedThing	renal amino acid absorption	A renal system process in which amino acids are taken up from the collecting ducts, glomerulus and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures.	tmpzr1t_l9r_go_relaxed.owl								hjd	2014-02-25T22:05:57Z					biological_process											owl:Class	
GO:0007124	biolink:NamedThing	pseudohyphal growth	The process in which cells grow as a chain of physically attached, elongated cells in response to an environmental stimulus or stimuli.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0070783	biolink:NamedThing	growth of unicellular organism as a thread of attached cells	A filamentous growth process in which cells remain attached after division and form thread-like filaments that may penetrate into a solid growth medium such as an agar plate, exhibited by unicellular fungi under certain growth conditions.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-07-07T02:21:14Z					biological_process											owl:Class	
GO:0036522	biolink:NamedThing	negative regulation by symbiont of host protein localization to phagocytic vesicle	Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of protein localisation to the host phagosome. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	inhibition of host protein localisation to phagosome|disruption of host protein localisation to phagosome|suppression of host protein localisation to phagosome							bf	2016-06-06T14:49:51Z					biological_process											owl:Class	
GO:0036521	biolink:NamedThing	modulation by symbiont of host protein localization to phagocytic vesicle	Any process in which an organism modulates the frequency, rate or extent of protein localisation to the host phagosome. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	modulation by symbiont of host protein localisation to phagosome							bf	2016-06-06T14:47:10Z					biological_process											owl:Class	
GO:0002304	biolink:NamedThing	gamma-delta intraepithelial T cell differentiation	The process in which a precursor cell type acquires the specialized features of a gamma-delta intraepithelial T cell. Intraepithelial T cells are found among epithelial cells in mucosal areas and have distinct phenotypes and developmental pathways.	tmpzr1t_l9r_go_relaxed.owl	gamma-delta intraepithelial T-lymphocyte differentiation|gamma-delta intraepithelial T cell development|gamma-delta intraepithelial T-cell differentiation|gamma-delta intraepithelial T lymphocyte differentiation					Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.								biological_process											owl:Class	
GO:0042492	biolink:NamedThing	gamma-delta T cell differentiation	The process in which a relatively unspecialized hemopoietic cell acquires specialized features of a gamma-delta T cell. A gamma-delta T cell is a T cell that expresses a gamma-delta T cell receptor complex.	tmpzr1t_l9r_go_relaxed.owl	gamma-delta T lymphocyte differentiation|gamma-delta T-cell differentiation|gamma-delta T-lymphocyte differentiation|gamma-delta T cell development					Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.								biological_process											owl:Class	
GO:0021569	biolink:NamedThing	rhombomere 3 development	The process whose specific outcome is the progression of rhombomere 3 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0009397	biolink:NamedThing	folic acid-containing compound catabolic process	The chemical reactions and pathways resulting in the breakdown of folic acid and its derivatives.	tmpzr1t_l9r_go_relaxed.owl	folate and derivative catabolic process|vitamin B9 and derivative catabolism|folate and derivative catabolism|folate-containing compound catabolism|folic acid-containing compound breakdown|folic acid and derivative catabolic process|vitamin M and derivative catabolism|folate-containing compound catabolic process|folic acid-containing compound catabolism|folic acid and derivative catabolism|vitamin B9 and derivative catabolic process|vitamin M and derivative catabolic process|folic acid-containing compound degradation													biological_process											owl:Class	
GO:1902844	biolink:NamedThing	positive regulation of spinal cord association neuron differentiation by negative regulation of canonical Wnt signaling pathway	A negative regulation of canonical Wnt signaling pathway that results in positive regulation of spinal cord association neuron differentiation.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of spinal cord association neuron differentiation by negative regulation of canonical Wnt signaling pathway|activation of spinal cord association neuron differentiation by negative regulation of canonical Wnt signaling pathway|upregulation of spinal cord association neuron differentiation by negative regulation of canonical Wnt signaling pathway|positive regulation of spinal cord dorsal interneuron differentiation by negative regulation of canonical Wnt signaling pathway|upregulation of spinal cord dorsal interneuron differentiation by negative regulation of canonical Wnt signaling pathway|up regulation of spinal cord dorsal interneuron differentiation by negative regulation of canonical Wnt signaling pathway|up regulation of spinal cord association neuron differentiation by negative regulation of canonical Wnt signaling pathway|activation of spinal cord dorsal interneuron differentiation by negative regulation of canonical Wnt signaling pathway|up-regulation of spinal cord dorsal interneuron differentiation by negative regulation of canonical Wnt signaling pathway							mr	2014-04-01T15:28:30Z					biological_process											owl:Class	
GO:0010034	biolink:NamedThing	response to acetate	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acetate stimulus.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0031765	biolink:NamedThing	type 2 galanin receptor binding	Binding to a type 2 galanin receptor.	tmpzr1t_l9r_go_relaxed.owl	type 2 galanin receptor ligand													molecular_function											owl:Class	
GO:0043801	biolink:NamedThing	hexulose-6-phosphate synthase activity	Catalysis of the reaction: D-ribulose 5-phosphate + formaldehyde = D-arabino-3-hexulose 6-phosphate.	tmpzr1t_l9r_go_relaxed.owl					EC:4.1.2.43|RHEA:25201|MetaCyc:R10-RXN									molecular_function											owl:Class	
GO:0060614	biolink:NamedThing	negative regulation of mammary gland development in males by androgen receptor signaling pathway	Any process that decreases the rate or extent of mammary gland development in the male by an androgen binding to its receptor, causing a change in state or activity of a cell.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of mammary gland development in males by androgen receptor signalling pathway							dph	2009-05-18T08:34:40Z					biological_process											owl:Class	
GO:0048214	biolink:NamedThing	regulation of Golgi vesicle fusion to target membrane	Any process that modulates the frequency, rate or extent of Golgi vesicle fusion to target membrane.	tmpzr1t_l9r_go_relaxed.owl						Note that GTP-binding Rab proteins serve as regulators of vesicle targeting and fusion.								biological_process											owl:Class	
GO:0050605	biolink:NamedThing	superoxide reductase activity	Catalysis of the reaction: superoxide + reduced rubredoxin + 2 H+ = H2O2 + rubredoxin.	tmpzr1t_l9r_go_relaxed.owl	rubredoxin:superoxide oxidoreductase activity|desulfoferrodoxin activity|neelaredoxin activity				EC:1.15.1.2|MetaCyc:1.15.1.2-RXN|RHEA:21324									molecular_function											owl:Class	
GO:2000988	biolink:NamedThing	regulation of hemicellulose catabolic process	Any process that modulates the frequency, rate or extent of hemicellulose catabolic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of hemicellulose catabolism							tt	2011-08-08T03:08:16Z					biological_process											owl:Class	
GO:0075193	biolink:NamedThing	regulation of haustorium mother cell formation	Any process that modulates the frequency, rate or extent of symbiont haustorium mother cell formation. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	regulation of haustorium mother cell formation on or near host					Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products from the symbiont involved in this process.								biological_process											owl:Class	
GO:0043532	biolink:NamedThing	angiostatin binding	Binding to angiostatin, a proteolytic product of plasminogen or plasmin containing at least one intact kringle domain, and which is an inhibitor of angiogenesis.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0045237	biolink:NamedThing	CXCR1 chemokine receptor binding	Binding to a CXCR1 chemokine receptor.	tmpzr1t_l9r_go_relaxed.owl	CXCR1 chemokine receptor ligand													molecular_function											owl:Class	
GO:0052896	biolink:NamedThing	spermidine oxidase (propane-1,3-diamine-forming) activity	Catalysis of the reaction: H(2)O + O(2) + spermidine = 1,3-diaminopropane + 4-aminobutanal + H(2)O(2).	tmpzr1t_l9r_go_relaxed.owl	polyamine oxidase (propane-1,3-diamine-forming) activity|spermidine:(acceptor) oxidoreductase activity				KEGG_REACTION:R01914|MetaCyc:RXN-10747|EC:1.5.3.14|RHEA:25820									molecular_function											owl:Class	
GO:1901441	biolink:NamedThing	poly(hydroxyalkanoate) biosynthetic process	The chemical reactions and pathways resulting in the formation of poly(hydroxyalkanoate).	tmpzr1t_l9r_go_relaxed.owl	poly(hydroxyalkanoate) formation|poly(hydroxyalkanoate) biosynthesis|poly(hydroxyalkanoate) anabolism|poly(hydroxyalkanoate) synthesis							tt	2012-10-02T01:48:33Z					biological_process											owl:Class	
GO:1900344	biolink:NamedThing	positive regulation of methane biosynthetic process from dimethyl sulfide	Any process that activates or increases the frequency, rate or extent of methane biosynthetic process from dimethyl sulfide.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of methane biosynthetic process from dimethyl sulfide|activation of methane biosynthetic process from dimethyl sulfide|up regulation of methane biosynthetic process from dimethyl sulfide|upregulation of methane biosynthetic process from dimethyl sulfide							tt	2012-04-06T02:06:56Z					biological_process											owl:Class	
GO:0062207	biolink:NamedThing	regulation of pattern recognition receptor signaling pathway	Any process that modulates the rate, frequency or extent of a pattern recognition receptor signaling pathway.	tmpzr1t_l9r_go_relaxed.owl								dph	2020-02-03T14:38:53Z					biological_process											owl:Class	
GO:0007521	biolink:NamedThing	muscle cell fate determination	The cell fate determination process in which a cell becomes capable of differentiating autonomously into a muscle cell regardless of its environment; upon determination, the cell fate cannot be reversed.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0052600	biolink:NamedThing	propane-1,3-diamine oxidase activity	Catalysis of the reaction: propane-1,3-diamine + H2O + O2 = 3-aminopropanal + NH3 + hydrogen peroxide + H+.	tmpzr1t_l9r_go_relaxed.owl	trimethylenediamine oxidase activity|1,3-diaminopropane oxidase activity|propane-1,3-diamine:oxygen oxidoreductase (deaminating) activity				EC:1.4.3.22|RHEA:30895|MetaCyc:RXN-6381|KEGG_REACTION:R03139									molecular_function											owl:Class	
GO:1903650	biolink:NamedThing	negative regulation of cytoplasmic transport	Any process that stops, prevents or reduces the frequency, rate or extent of cytoplasmic transport.	tmpzr1t_l9r_go_relaxed.owl	downregulation of cytoplasmic transport|inhibition of cytoplasmic streaming|down-regulation of cytoplasmic transport|inhibition of cytoplasmic transport|down-regulation of cytoplasmic streaming|downregulation of cytoplasmic streaming|down regulation of cytoplasmic transport|negative regulation of cytoplasmic streaming|down regulation of cytoplasmic streaming							jl	2014-11-24T13:38:26Z					biological_process											owl:Class	
GO:0047965	biolink:NamedThing	glycoprotein O-fatty-acyltransferase activity	Catalysis of the reaction: palmitoyl-CoA + mucus glycoprotein = CoA + O-palmitoylglycoprotein.	tmpzr1t_l9r_go_relaxed.owl	fatty-acyl-CoA:mucus-glycoprotein fatty-acyltransferase activity|protein acyltransferase activity				EC:2.3.1.142|MetaCyc:GLYCOPROTEIN-O-FATTY-ACYLTRANSFERASE-RXN									molecular_function											owl:Class	
GO:0016416	biolink:NamedThing	O-palmitoyltransferase activity	Catalysis of the transfer of a palmitoyl group to an oxygen atom on the acceptor molecule.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-2453855|Reactome:R-HSA-2466710|Reactome:R-HSA-2404137									molecular_function											owl:Class	
GO:2000835	biolink:NamedThing	negative regulation of androgen secretion	Any process that stops, prevents or reduces the frequency, rate or extent of androgen secretion.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-07-26T08:39:48Z					biological_process											owl:Class	
GO:0030328	biolink:NamedThing	prenylcysteine catabolic process	The chemical reactions and pathways resulting in the breakdown of prenylcysteine, 3-methyl-2-buten-1-yl-cysteine, a derivative of the amino acid cysteine formed by the covalent addition of a prenyl residue.	tmpzr1t_l9r_go_relaxed.owl	prenylcysteine breakdown|prenylcysteine degradation|prenylcysteine catabolism													biological_process											owl:Class	
GO:1903648	biolink:NamedThing	positive regulation of chlorophyll catabolic process	Any process that activates or increases the frequency, rate or extent of chlorophyll catabolic process.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of chlorophyll degradation|up regulation of chlorophyll breakdown|positive regulation of chlorophyll breakdown|up regulation of chlorophyll catabolic process|positive regulation of chlorophyll catabolism|activation of chlorophyll breakdown|up regulation of chlorophyll degradation|up-regulation of chlorophyll catabolic process|up-regulation of chlorophyll catabolism|activation of chlorophyll catabolism|activation of chlorophyll degradation|upregulation of chlorophyll catabolism|activation of chlorophyll catabolic process|upregulation of chlorophyll breakdown|up-regulation of chlorophyll breakdown|up regulation of chlorophyll catabolism|upregulation of chlorophyll catabolic process|positive regulation of chlorophyll degradation|upregulation of chlorophyll degradation							tb	2014-11-22T00:18:34Z					biological_process											owl:Class	
GO:0018415	biolink:NamedThing	iron incorporation into iron-sulfur cluster via tris-L-cysteinyl L-cysteine persulfido bis-L-glutamato L-histidino nickel triiron disulfide trioxide	The incorporation of iron into a 3Fe-2S cluster via tris-L-cysteinyl L-cysteine persulfido bis-L-glutamato L-histidino nickel triiron disulfide trioxide.	tmpzr1t_l9r_go_relaxed.owl	iron incorporation into iron-sulphur cluster via tris-L-cysteinyl L-cysteine persulphido bis-L-glutamato L-histidino nickel triiron disulphide trioxide				RESID:AA0292									biological_process											owl:Class	
GO:0033197	biolink:NamedThing	response to vitamin E	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin E stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to DL-alpha-tocopherol acetate|response to O-Acetyl-alpha-tocopherol|response to DL-alpha-tocopheryl acetate													biological_process											owl:Class	
GO:0009764	biolink:NamedThing	PEP carboxykinase C4 photosynthesis	The process of C4 photosynthesis, as it occurs in plants in which the enzyme decarboxylating C4 acids in the bundle sheath is phosphoenolpyruvate carboxykinase (PEPCK).	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0009760	biolink:NamedThing	C4 photosynthesis	The combination of atmospheric CO2 with a 3-carbon molecule phosphoenol pyruvate (PEP) in the mesophyll cells to make a 4-carbon acid which is immediately converted to malic acid. The malic acid is then passed across to the bundle sheath cells where it is broken down again to pyruvic acid and CO2. The acid is passed back to the mesophyll cells to be used again, while the CO2 is fed into the reductive pentose-phosphate cycle (Calvin cycle) and converted into sugar and starch.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:C4_carbon_fixation									biological_process											owl:Class	
GO:0051412	biolink:NamedThing	response to corticosterone	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a corticosterone stimulus. Corticosterone is a 21 carbon steroid hormone of the corticosteroid type, produced in the cortex of the adrenal glands. In many species, corticosterone is the principal glucocorticoid, involved in regulation of fuel metabolism, immune reactions, and stress responses.	tmpzr1t_l9r_go_relaxed.owl	response to corticosterone stimulus													biological_process											owl:Class	
GO:0051385	biolink:NamedThing	response to mineralocorticoid	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mineralocorticoid stimulus. Mineralocorticoids are hormonal C21 corticosteroids synthesized from cholesterol and characterized by their similarity to aldosterone. Mineralocorticoids act primarily on water and electrolyte balance.	tmpzr1t_l9r_go_relaxed.owl	response to mineralocorticoid stimulus													biological_process											owl:Class	
GO:1904147	biolink:NamedThing	response to nonylphenol	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nonylphenol stimulus.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-04-14T17:01:44Z					biological_process											owl:Class	
GO:0010999	biolink:NamedThing	regulation of eIF2 alpha phosphorylation by heme	Any process that modulates the rate, frequency, or extent of eIF2 alpha phosphorylation as a result of heme levels.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-06-10T11:42:10Z					biological_process											owl:Class	
GO:2001157	biolink:NamedThing	negative regulation of proline catabolic process to glutamate	Any process that stops, prevents or reduces the frequency, rate or extent of proline catabolic process to glutamate.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of proline oxidation|negative regulation of proline breakdown to glutamate|negative regulation of proline degradation to glutamate							mcc	2011-10-25T08:54:43Z					biological_process											owl:Class	
GO:0047290	biolink:NamedThing	(alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3)-N-acetyl-galactosaminide 6-alpha-sialyltransferase activity	Catalysis of the reaction: alpha-N-acetylneuraminyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-D-galactosaminyl-R + CMP-N-acetyl-beta-neuraminate = alpha-N-acetylneuraminyl-(2->3)-beta-D-galactosyl-(1->3)-[N-acetyl-alpha-neuraminyl-(2->6)]-N-acetyl-D-galactosaminyl-R + CMP.	tmpzr1t_l9r_go_relaxed.owl	SIAT7|NeuAc-alpha-2,3-Gal-beta-1,3-GalNAc-alpha-2,6-sialyltransferase activity|alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3-N-acetyl-galactosaminide alpha-2,6-sialyltransferase activity|sialyltransferase 3C activity|sialyltransferase 7D activity|CMP-N-acetylneuraminate:(alpha-N-acetylneuraminyl-2,3-beta-D-galactosyl-1,3)-N-acetyl-D-galactosaminide alpha-2,6-N-acetylneuraminyl-transferase activity|ST6GALNAC activity|cytidine monophosphoacetylneuraminate-(alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide-alpha-2,6-sialyltransferase activity|(alpha-N-acetylneuraminyl-2,3-alpha-galactosyl-1,3)-N-acetyl-galactosaminide alpha-2,6-sialyltransferase activity|(alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity				KEGG_REACTION:R04635|MetaCyc:2.4.99.7-RXN|Reactome:R-HSA-981809|RHEA:53896|EC:2.4.99.7									molecular_function											owl:Class	
GO:0003961	biolink:NamedThing	O-acetylhomoserine aminocarboxypropyltransferase activity	Catalysis of the reaction: O-acetyl-L-homoserine + methanethiol = L-methionine + acetate. Also reacts with other thiols and H2S, producing homocysteine or thioethers.	tmpzr1t_l9r_go_relaxed.owl	L-methionine formation, direct, from O-acetyl-L-homoserine|O-acetylhomoserine (thiol)-lyase activity|O-acetylhomoserine sulfhydrolase activity|O-acetyl-L-homoserine sulfhydrolase activity|O-acetyl-L-homoserine acetate-lyase (adding methanethiol) activity|L-methionine biosynthetic process, direct, from O-acetyl-L-homoserine|methionine biosynthetic process, direct, from O-acetyl-L-homoserine|L-methionine anabolism, direct, from O-acetyl-L-homoserine|O-acetyl-L-homoserine:methanethiol 3-amino-3-carboxypropyltransferase activity|OAH sulfhydrylase activity|L-methionine synthesis, direct, from O-acetyl-L-homoserine				MetaCyc:O-ACETYLHOMOSERINE-THIOL-LYASE-RXN|RHEA:10048|EC:2.5.1.49	Note that this function was formerly EC:4.2.99.10.						GO:0019282		molecular_function											owl:Class	
GO:1903097	biolink:NamedThing	regulation of CENP-A containing nucleosome assembly	Any process that modulates the rate, frequency or extent of the formation of nucleosomes containing the histone H3 variant CENP-A to form centromeric chromatin. This specialised chromatin occurs at centromeric region in point centromeres,  and the central core in modular centromeres.	tmpzr1t_l9r_go_relaxed.owl	regulation of CenH3-containing nucleosome assembly at centromere|regulation of centromeric DNA replication-independent nucleosome assembly|regulation of centromere-specific nucleosome assembly|regulation of DNA replication-independent nucleosome assembly at centromere|regulation of centromere-specific histone exchange|regulation of CENP-A loading|regulation of centromere specific nucleosome exchange|regulation of CENP-A deposition							vw	2014-06-03T16:15:30Z					biological_process											owl:Class	
GO:0019445	biolink:NamedThing	tyrosine catabolic process to fumarate	The chemical reactions and pathways resulting in the breakdown of tyrosine into other compounds, including fumarate.	tmpzr1t_l9r_go_relaxed.owl	tyrosine degradation to fumarate|tyrosine breakdown to fumarate				MetaCyc:TYRFUMCAT-PWY									biological_process											owl:Class	
GO:0005779	biolink:NamedThing	integral component of peroxisomal membrane	The component of the peroxisomal membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.	tmpzr1t_l9r_go_relaxed.owl	integral to peroxisomal membrane													cellular_component											owl:Class	
GO:0034411	biolink:NamedThing	cell wall (1->3)-beta-D-glucan biosynthetic process	The chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds, found in the walls of cells.	tmpzr1t_l9r_go_relaxed.owl	cell wall 1,3-beta-glucan formation|cell wall 1,3-beta-glucan synthesis|cell wall beta-1,3-glucan formation|cell wall 1,3-beta-D-glucan biosynthetic process|cell wall 1,3-beta-glucan anabolism|cell wall 1,3-beta-glucan biosynthesis|cell wall beta-1,3-glucan biosynthetic process|cell wall beta-1,3-glucan anabolism|cell wall beta-1,3-glucan biosynthesis|cell wall beta-1,3-glucan synthesis|cell wall 1,3-beta-glucan biosynthetic process													biological_process											owl:Class	
GO:0006079	biolink:NamedThing	(1->6)-beta-D-glucan catabolic process	The chemical reactions and pathways resulting in the breakdown of (1->6)-beta-D-glucans.	tmpzr1t_l9r_go_relaxed.owl	1,6-beta-D-glucan catabolic process|1,6-beta-D-glucan breakdown|beta-1,6 glucan degradation|beta-1,6 glucan catabolism|beta-1,6 glucan breakdown|beta-1,6 glucan catabolic process|1,6-beta-D-glucan catabolism|1,6-beta-D-glucan degradation													biological_process											owl:Class	
GO:0006849	biolink:NamedThing	plasma membrane pyruvate transport	The directed movement of pyruvate, 2-oxopropanoate, across a plasma membrane.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1901475	biolink:NamedThing	pyruvate transmembrane transport	The directed movement of pyruvate across a membrane.	tmpzr1t_l9r_go_relaxed.owl	pyruvate membrane transport					Note that this term is not intended for use in annotating lateral movement within membranes.		tb	2012-10-04T20:52:54Z					biological_process											owl:Class	
GO:0047789	biolink:NamedThing	creatininase activity	Catalysis of the reaction: creatinine + H(2)O = creatine.	tmpzr1t_l9r_go_relaxed.owl	creatinine amidohydrolase activity|creatinine hydrolase				KEGG_REACTION:R01884|EC:3.5.2.10|MetaCyc:CREATININASE-RXN|RHEA:14533									molecular_function											owl:Class	
GO:0051034	biolink:NamedThing	tRNA transmembrane transporter activity	Enables the transfer of tRNA, transfer ribonucleic acid, from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0016212	biolink:NamedThing	kynurenine-oxoglutarate transaminase activity	Catalysis of the reaction: L-kynurenine + 2-oxoglutarate = 4-(2-aminophenyl)-2,4-dioxobutanoate + L-glutamate.	tmpzr1t_l9r_go_relaxed.owl	kynurenine aminotransferase activity|L-kynurenine aminotransferase activity|kynurenine-oxoglutarate aminotransferase activity|L-kynurenine:2-oxoglutarate aminotransferase activity|kynurenine--oxoglutarate aminotransferase activity|kynurenine transaminase (cyclizing)|kynurenine 2-oxoglutarate transaminase activity				MetaCyc:2.6.1.7-RXN|EC:2.6.1.7|Reactome:R-HSA-893583|RHEA:20964|Reactome:R-HSA-901097|Reactome:R-HSA-893596									molecular_function											owl:Class	
GO:0036137	biolink:NamedThing	kynurenine aminotransferase activity	Catalysis of the transfer of an amino group from kynurenine to an acceptor, usually a 2-oxo acid.	tmpzr1t_l9r_go_relaxed.owl	L-kynurenine transaminase activity|kynurenine-oxo-acid transaminase activity							bf	2012-03-06T02:16:48Z					molecular_function											owl:Class	
GO:0070744	biolink:NamedThing	interleukin-27 complex	A protein complex that is composed of an interleukin-27p28 subunit (product of the IL27 gene) and an EBI3 subunit and is secreted into the extracellular space.	tmpzr1t_l9r_go_relaxed.owl	IL27|EBI3|IL-27 complex|p28					Note that this heterodimeric cytokine utilizes the same EBI3 subunit (product of EBI3, Epstein-Barr virus induced gene 3) as its beta chain as IL-35 uses for its beta chain. Also note that the product of the IL27 gene is the alpha subunit of IL-27. The functional IL-27 protein complex requires both subunits.		mah	2009-06-23T01:09:58Z					cellular_component											owl:Class	
GO:0103012	biolink:NamedThing	ferredoxin-thioredoxin reductase activity	Catalysis of the reaction: 2 H+ + 2 a reduced ferredoxin + an oxidized thioredoxin = 2 an oxidized ferredoxin + a reduced thioredoxin, involving a 4Fe-4S cluster and an adjacent active-site disulfide.	tmpzr1t_l9r_go_relaxed.owl	ferredoxin:thioredoxin reductase activity	https://github.com/geneontology/go-ontology/issues/18939			RHEA:42336|EC:1.8.7.2|MetaCyc:RXN-9944							GO:0030385		molecular_function											owl:Class	
GO:0016673	biolink:NamedThing	oxidoreductase activity, acting on a sulfur group of donors, iron-sulfur protein as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which a sulfur-containing group acts as a hydrogen or electron donor and reduces an iron-sulfur protein.	tmpzr1t_l9r_go_relaxed.owl	oxidoreductase activity, acting on sulphur group of donors, iron-sulphur protein as acceptor				EC:1.8.7.-									molecular_function											owl:Class	
GO:0097684	biolink:NamedThing	dinoflagellate antapex	The anterior most point of a dinoflagellate hypocone.	tmpzr1t_l9r_go_relaxed.owl	antapex					The term name refers to a taxonomic group to make the label unique with respect to similarly-named anatomical structures.		pr	2014-12-18T09:32:10Z					cellular_component											owl:Class	
GO:0033294	biolink:NamedThing	ectoine binding	Binding to ectoine, 1,4,5,6-tetrahydro-2-methyl-4-pyrimidinecarboxylic acid.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1900808	biolink:NamedThing	fumigaclavine C catabolic process	The chemical reactions and pathways resulting in the breakdown of fumigaclavine C.	tmpzr1t_l9r_go_relaxed.owl	fumigaclavine C catabolism|fumigaclavine C breakdown|fumigaclavine C degradation							di	2012-06-04T09:59:55Z					biological_process											owl:Class	
GO:1900807	biolink:NamedThing	fumigaclavine C metabolic process	The chemical reactions and pathways involving fumigaclavine C.	tmpzr1t_l9r_go_relaxed.owl	fumigaclavine C metabolism							di	2012-06-04T09:59:32Z					biological_process											owl:Class	
GO:0007537	biolink:NamedThing	inactivation of recombination (HML)	The inactivation of recombination at sequences around a mating type donor locus, with the consequence that the other donor is the only one available for mating type switching; exemplified by the HML locus and surrounding sequences on Chromosome III in Saccharomyces cerevisiae.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0090393	biolink:NamedThing	sepal giant cell development	The process aimed at the progression of a sepal giant cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.	tmpzr1t_l9r_go_relaxed.owl	sepal giant cell formation							tb	2010-12-14T04:44:34Z					biological_process											owl:Class	
GO:0150013	biolink:NamedThing	negative regulation of neuron projection arborization	Any process that stops, prevents or reduces the frequency, rate or extent of the process in which the anatomical structures of a neuron projection are generated and organized into branches.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of neurite arborization|negative regulation of neurite branching|negative regulation of neuron projection branching							bc	2017-12-13T16:50:53Z					biological_process											owl:Class	
GO:0051660	biolink:NamedThing	establishment of centrosome localization	The directed movement of the centrosome to a specific location.	tmpzr1t_l9r_go_relaxed.owl	centrosome positioning|establishment of centrosome localisation													biological_process											owl:Class	
GO:0090120	biolink:NamedThing	lysosome to ER cholesterol transport	The directed movement of cholesterol, cholest-5-en-3-beta-ol, or cholesterol-containing compounds, from the lysosome to the endoplasmic reticulum.	tmpzr1t_l9r_go_relaxed.owl	lysosome to endoplasmic reticulum cholesterol transport							tb	2009-12-07T12:22:12Z					biological_process											owl:Class	
GO:0060745	biolink:NamedThing	mammary gland branching involved in pregnancy	The process in which the branching structure of the mammary gland duct is generated and organized as a part of pregnancy.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-06-22T08:25:19Z					biological_process											owl:Class	
GO:0030208	biolink:NamedThing	dermatan sulfate biosynthetic process	The chemical reactions and pathways resulting in the formation of dermatan sulfate, any glycosaminoglycan with repeats consisting of beta-(1,4)-linked L-iduronyl-beta-(1,3)-N-acetyl-D-galactosamine 4-sulfate units.	tmpzr1t_l9r_go_relaxed.owl	chondroitin sulfate B biosynthetic process|dermatan sulfate anabolism|dermatan sulfate formation|dermatan sulphate biosynthesis|dermatan sulfate synthesis|chondroitin sulfate B biosynthesis|dermatan sulfate biosynthesis|dermatan sulphate biosynthetic process													biological_process											owl:Class	
GO:0030205	biolink:NamedThing	dermatan sulfate metabolic process	The chemical reactions and pathways involving dermatan sulfate, any of a group of glycosaminoglycans with repeats consisting of beta-(1,4)-linked L-iduronyl-beta-(1,3)-N-acetyl-D-galactosamine 4-sulfate units. They are important components of ground substance or intercellular cement of skin and some connective tissues.	tmpzr1t_l9r_go_relaxed.owl	dermatan sulphate metabolism|chondroitin sulfate B metabolic process|dermatan sulfate metabolism|chondroitin sulfate B metabolism|dermatan sulphate metabolic process													biological_process											owl:Class	
GO:0050780	biolink:NamedThing	dopamine receptor binding	Binding to a dopamine receptor.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1902099	biolink:NamedThing	regulation of metaphase/anaphase transition of cell cycle	Any process that modulates the frequency, rate or extent of metaphase/anaphase transition of cell cycle.	tmpzr1t_l9r_go_relaxed.owl								jl	2013-05-02T12:45:15Z					biological_process											owl:Class	
GO:0033045	biolink:NamedThing	regulation of sister chromatid segregation	Any process that modulates the frequency, rate or extent of sister chromatid segregation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1900056	biolink:NamedThing	negative regulation of leaf senescence	Any process that stops, prevents or reduces the frequency, rate or extent of leaf senescence.	tmpzr1t_l9r_go_relaxed.owl	inhibition of leaf senescence|downregulation of leaf senescence|down regulation of leaf senescence|down-regulation of leaf senescence							tb	2012-01-24T11:51:32Z					biological_process											owl:Class	
GO:0039724	biolink:NamedThing	suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IKBKE activity	Any process in which a virus stops, prevents, or reduces a host viral-induced cytoplasmic pattern recognition receptor signaling pathway by reducing the activity of host I-kappa-B kinase epsilon (IKBKE/IKK-epsilon/IKK-E).	tmpzr1t_l9r_go_relaxed.owl	inhibition of host IKBKE by virus|suppression by virus of host IKBKE activity	https://github.com/geneontology/go-ontology/issues/21985						bf	2014-01-06T12:15:03Z					biological_process											owl:Class	
GO:0035699	biolink:NamedThing	T-helper 17 cell extravasation	The migration of a T-helper 17 cell from the blood vessels into the surrounding tissue.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-02-28T03:13:27Z					biological_process											owl:Class	
GO:0035684	biolink:NamedThing	helper T cell extravasation	The migration of a helper T cell from the blood vessels into the surrounding tissue. A helper T-cell is an effector T cell that provides help in the form of secreted cytokines to other immune cells.	tmpzr1t_l9r_go_relaxed.owl	T-helper cell extravasation|helper T-cell extravasation							bf	2011-02-23T01:11:05Z					biological_process											owl:Class	
GO:0008512	biolink:NamedThing	sulfate:proton symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sulfate(out) + H+(out) = sulfate(in) + H+(in).	tmpzr1t_l9r_go_relaxed.owl	sulfate/hydrogen symporter activity|sulfate:hydrogen symporter activity|sulphate:hydrogen symporter activity													molecular_function											owl:Class	
GO:0008271	biolink:NamedThing	secondary active sulfate transmembrane transporter activity	Enables the secondary active transfer of sulfate from one side of a membrane to the other. Secondary active transport is the transfer of a solute across a membrane, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters.	tmpzr1t_l9r_go_relaxed.owl	sulfate porter activity|secondary active sulphate transmembrane transporter activity|sulphate porter activity													molecular_function											owl:Class	
GO:2001223	biolink:NamedThing	negative regulation of neuron migration	Any process that stops, prevents or reduces the frequency, rate or extent of neuron migration.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of neuronal migration|negative regulation of neuron guidance|negative regulation of neuron chemotaxis							kmv	2011-11-17T10:01:45Z					biological_process											owl:Class	
GO:0034727	biolink:NamedThing	piecemeal microautophagy of the nucleus	Degradation of a cell nucleus by lysosomal microautophagy.	tmpzr1t_l9r_go_relaxed.owl	PMN													biological_process											owl:Class	
GO:0009924	biolink:NamedThing	octadecanal decarbonylase activity	Catalysis of the reaction: octadecanal = heptadecane + CO.	tmpzr1t_l9r_go_relaxed.owl	octadecanal alkane-lyase activity				RHEA:30415|MetaCyc:OCTADECANAL-DECARBONYLASE-RXN|EC:4.1.99.5									molecular_function											owl:Class	
GO:0071771	biolink:NamedThing	aldehyde decarbonylase activity	Catalysis of the reaction: a C(n) aldehyde = C(n-1) alkane + CO.	tmpzr1t_l9r_go_relaxed.owl	decarbonylase activity							mah	2010-04-01T12:02:50Z					molecular_function											owl:Class	
GO:0043992	biolink:NamedThing	histone acetyltransferase activity (H3-K9 specific)	Catalysis of the reaction: acetyl-CoA + histone H3 L-lysine (position 9) = CoA + histone H3 N6-acetyl-L-lysine (position 9).	tmpzr1t_l9r_go_relaxed.owl	histone lysine N-acetyltransferase activity (H3-K9 specific)													molecular_function											owl:Class	
GO:0010365	biolink:NamedThing	positive regulation of ethylene biosynthetic process	Any process that activates or increases the frequency, rate or extent of an ethylene biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0097599	biolink:NamedThing	xylanase activity	Catalysis of the hydrolysis of xylans, homopolysaccharides composed of xylose residues.	tmpzr1t_l9r_go_relaxed.owl	xylosidase activity							pr	2014-05-06T13:46:48Z					molecular_function											owl:Class	
GO:0008520	biolink:NamedThing	L-ascorbate:sodium symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: L-ascorbate(out) + Na+(out) = L-ascorbate(in) + Na+(in).	tmpzr1t_l9r_go_relaxed.owl	sodium-dependent L-ascorbate transmembrane transporter activity|sodium-dependent L-ascorbic acid transporter				TC:2.A.40.6.1			mah	2009-09-01T02:25:22Z			GO:0070890		molecular_function											owl:Class	
GO:0052594	biolink:NamedThing	aminoacetone:oxygen oxidoreductase(deaminating) activity	Catalysis of the reaction: aminoacetone + H2O + O2 = methylglyoxal + NH3 + hydrogen peroxide + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:AMACETOXID-RXN|KEGG_REACTION:R02529|RHEA:28186|EC:1.4.3.21									molecular_function											owl:Class	
GO:0061217	biolink:NamedThing	regulation of mesonephros development	Any process that modulates the rate, frequency or extent of mesonephros development. Mesonephros development is the process whose specific outcome is the progression of the mesonephros over time, from its formation to the mature structure. The mesonephros is an endocrine and metabolic organ that filters the blood and excretes the end products of body metabolism in the form of urine.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-08-17T03:35:31Z					biological_process											owl:Class	
GO:0052732	biolink:NamedThing	phosphoethanolamine phosphatase activity	Catalysis of the reaction: O-phosphoethanolamine + H2O = ethanolamine + phosphate.	tmpzr1t_l9r_go_relaxed.owl	3X11A|PHOSPHO1|phosphoethanolamine phosphohydrolase activity				MetaCyc:RXN-7948|KEGG_REACTION:R06870|RHEA:16089|Reactome:R-HSA-1483096|EC:3.1.3.75			ai	2011-08-16T04:09:19Z					molecular_function											owl:Class	
GO:1905782	biolink:NamedThing	positive regulation of phosphatidylserine exposure on apoptotic cell surface	Any process that activates or increases the frequency, rate or extent of phosphatidylserine exposure on apoptotic cell surface.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of phosphatidylserine exposure on apoptotic cell surface|upregulation of phosphatidylserine exposure on apoptotic cell surface|positive regulation of externalization of phosphatidylserine|up-regulation of externalization of phosphatidylserine|up regulation of externalization of phosphatidylserine|activation of phosphatidylserine exposure on apoptotic cell surface|upregulation of externalization of phosphatidylserine|up regulation of phosphatidylserine exposure on apoptotic cell surface|activation of externalization of phosphatidylserine							kmv	2017-01-04T15:19:22Z					biological_process											owl:Class	
GO:0097556	biolink:NamedThing	left posteriolateral flagellum	A cilium (also called flagellum) found in Giardia species (trophozoite stage). It is nucleated by the left posteriolateral basal body and extends cytoplasmically toward the cell posterior, marking the left anterior boundary of the lateral shield and the left lateral region of the funis before exiting at the left lateral region of the cell body.	tmpzr1t_l9r_go_relaxed.owl	left posterolateral flagellum|left posterolateral cilium|left posteriolateral cilium					Note that we deem cilium and microtubule-based flagellum to be equivalent; the primary term name reflects frequency of use. Also note that, due to the asymmetric nature of the Giardia trophozoite, this term is defined spatially as the trophozoite is viewed from the dorsal side, with the two nuclei dorsal to the ventral disc, and the ventral disc toward the anterior.		pr	2014-02-05T13:21:09Z					cellular_component											owl:Class	
GO:0050436	biolink:NamedThing	microfibril binding	Binding to a microfibril, any small fibril occurring in biological material.	tmpzr1t_l9r_go_relaxed.owl						See also the cellular component term 'microfibril ; GO:0001527'.								molecular_function											owl:Class	
GO:0042355	biolink:NamedThing	L-fucose catabolic process	The chemical reactions and pathways resulting in the breakdown of L-fucose (6-deoxy-Lgalactose).	tmpzr1t_l9r_go_relaxed.owl	L-fucose catabolism|L-fucose degradation|L-fucose breakdown													biological_process											owl:Class	
GO:0042354	biolink:NamedThing	L-fucose metabolic process	The chemical reactions and pathways involving L-fucose, 6-deoxy-L-galactose, a sugar that occurs in fucans, a class of polysaccharides in seaweeds, especially Fucus species, and in the cell wall matrix of higher plants.	tmpzr1t_l9r_go_relaxed.owl	L-fucose metabolism													biological_process											owl:Class	
GO:0031808	biolink:NamedThing	H2 histamine receptor binding	Binding to a H2 histamine receptor.	tmpzr1t_l9r_go_relaxed.owl	H2 histamine receptor ligand													molecular_function											owl:Class	
GO:0031806	biolink:NamedThing	G protein-coupled histamine receptor binding	Binding to a G protein-coupled (metabotropic) histamine receptor.	tmpzr1t_l9r_go_relaxed.owl	metabotropic histamine receptor binding|metabotropic histamine receptor ligand|G-protein coupled histamine receptor binding													molecular_function											owl:Class	
GO:0031865	biolink:NamedThing	EP2 subtype prostaglandin E2 receptor binding	Binding to an EP2 subtype prostaglandin E2 receptor.	tmpzr1t_l9r_go_relaxed.owl	prostanoid EP2 receptor binding|EP2 subtype prostaglandin E2 receptor ligand													molecular_function											owl:Class	
GO:0042725	biolink:NamedThing	thiamine-containing compound catabolic process	The chemical reactions and pathways resulting in the breakdown of thiamine (vitamin B1), and compounds derived from it.	tmpzr1t_l9r_go_relaxed.owl	thiamine and derivative catabolism|thiamine-containing compound breakdown|thiamin and derivative catabolism|thiamine-containing compound degradation|thiamine-containing compound catabolism|vitamin B1 and derivative catabolic process|thiamin-containing compound catabolic process|thiamin and derivative catabolic process|thiamine and derivative catabolic process|vitamin B1 and derivative catabolism													biological_process											owl:Class	
GO:0072529	biolink:NamedThing	pyrimidine-containing compound catabolic process	The chemical reactions and pathways resulting in the breakdown of a pyrimidine-containing compound, i.e. any compound that contains pyrimidine or a formal derivative thereof.	tmpzr1t_l9r_go_relaxed.owl	pyrimidine-containing compound catabolism|pyrimidine-containing compound breakdown|pyrimidine-containing compound degradation|pyrimidine and derivative catabolic process							mah	2011-01-04T03:27:51Z					biological_process											owl:Class	
GO:0099644	biolink:NamedThing	protein localization to presynaptic membrane	A process in which a protein is transported to, or maintained in, a location within a presynaptic membrane.	tmpzr1t_l9r_go_relaxed.owl	protein localisation in presynaptic membrane|protein localisation to presynaptic membrane|protein localization in presynaptic membrane													biological_process											owl:Class	
GO:1905383	biolink:NamedThing	protein localization to presynapse	A process in which a protein is transported to, or maintained in, a location within a presynapse.	tmpzr1t_l9r_go_relaxed.owl	recruitment of presynaptic proteins|protein localization in presynapse|protein localisation to presynapse|protein localisation in presynapse							dos	2016-08-18T14:42:59Z					biological_process											owl:Class	
GO:0140107	biolink:NamedThing	high-affinity potassium ion transmembrane transporter activity	Enables the transfer of potassium ions from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.	tmpzr1t_l9r_go_relaxed.owl								pg	2017-10-12T09:54:39Z					molecular_function											owl:Class	
GO:0044176	biolink:NamedThing	host cell filopodium	Thin, stiff protrusion extended by the leading edge of a motile host cell such as a crawling fibroblast or amoeba, or an axonal growth cone; usually approximately 0.1 um wide, 5-10 um long, can be up to 50 um long in axon growth cones; contains a loose bundle of about 20 actin filaments oriented with their plus ends pointing outward.	tmpzr1t_l9r_go_relaxed.owl	host filopodium							jl	2009-09-04T03:06:59Z					cellular_component											owl:Class	
GO:0044157	biolink:NamedThing	host cell projection	A prolongation or process extending from a host cell, e.g. a flagellum or axon.	tmpzr1t_l9r_go_relaxed.owl								jl	2009-08-11T04:07:24Z					cellular_component											owl:Class	
GO:0043228	biolink:NamedThing	non-membrane-bounded organelle	Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane. Includes ribosomes, the cytoskeleton and chromosomes.	tmpzr1t_l9r_go_relaxed.owl	biological condensate|non-membrane-enclosed organelle	https://github.com/geneontology/go-ontology/issues/21881			NIF_Subcellular:sao1456184038									cellular_component											owl:Class	
GO:0009178	biolink:NamedThing	pyrimidine deoxyribonucleoside monophosphate catabolic process	The chemical reactions and pathways resulting in the breakdown of pyrimidine deoxynucleoside monophosphate, a compound consisting of a pyrimidine base linked to a deoxyribose sugar esterified with phosphate on the sugar.	tmpzr1t_l9r_go_relaxed.owl	pyrimidine deoxyribonucleoside monophosphate catabolism|pyrimidine deoxyribonucleoside monophosphate breakdown|pyrimidine deoxyribonucleoside monophosphate degradation													biological_process											owl:Class	
GO:0031580	biolink:NamedThing	membrane raft distribution	The process that establishes the spatial arrangement of membrane rafts within a cellular membrane.	tmpzr1t_l9r_go_relaxed.owl	lipid raft distribution													biological_process											owl:Class	
GO:0044365	biolink:NamedThing	envenomation resulting in modulation of platelet aggregation in other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with a resultant change to the frequency, rate or extent of platelet aggregation in the bitten organism.	tmpzr1t_l9r_go_relaxed.owl	envenomation resulting in regulation of platelet aggregation in other organism							jl	2011-10-27T02:36:43Z					biological_process											owl:Class	
GO:0102263	biolink:NamedThing	tRNA-dihydrouridine17 synthase activity	Catalysis of the reaction: a 5,6-dihydrouracil17 in tRNA + NAD(P) <=> H+ + a uracil17 in tRNA + NAD(P)H.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-12455|EC:1.3.1.88									molecular_function											owl:Class	
GO:0061520	biolink:NamedThing	Langerhans cell differentiation	The process in which a precursor cell type acquires the specialized features of a Langerhans cell.	tmpzr1t_l9r_go_relaxed.owl								dph	2013-04-18T13:29:07Z					biological_process											owl:Class	
GO:0039722	biolink:NamedThing	suppression by virus of host toll-like receptor signaling pathway	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of toll-like receptor (TLR) signaling in the host organism.	tmpzr1t_l9r_go_relaxed.owl	inhibition of host TLR pathway by virus|suppression by virus of host TLR signaling pathway							bf	2014-01-06T11:39:58Z					biological_process											owl:Class	
GO:0002486	biolink:NamedThing	antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent	The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class I protein complex following intracellular transport via a TAP-independent ER pathway. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell and becomes associated with the MHC class I molecule in the ER following transport from the cytosol via a TAP-independent pathway. Class I here refers to classical class I molecules.	tmpzr1t_l9r_go_relaxed.owl	endogenous peptide antigen processing and presentation via MHC class I via ER pathway, TAP-independent|TAP-independent endogenous peptide antigen processing and presentation via MHC class I via ER pathway|TAP-independent antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway													biological_process											owl:Class	
GO:0002484	biolink:NamedThing	antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway	The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class I protein complex following intracellular transport via an ER pathway. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell and becomes associated with the MHC class I molecule in the ER. Class I here refers to classical class I molecules.	tmpzr1t_l9r_go_relaxed.owl	endogenous peptide antigen processing and presentation via MHC class I via ER pathway													biological_process											owl:Class	
GO:0004664	biolink:NamedThing	prephenate dehydratase activity	Catalysis of the reaction: prephenate = phenylpyruvate + H2O + CO2.	tmpzr1t_l9r_go_relaxed.owl	prephenate hydro-lyase (decarboxylating; phenylpyruvate-forming)|prephenate hydro-lyase (decarboxylating)				RHEA:21648|MetaCyc:PREPHENATEDEHYDRAT-RXN|EC:4.2.1.51									molecular_function											owl:Class	
GO:0032247	biolink:NamedThing	negative regulation of purine nucleoside transport	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a purine nucleoside into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	down regulation of purine nucleoside transport|downregulation of purine nucleoside transport|down-regulation of purine nucleoside transport|inhibition of purine nucleoside transport													biological_process											owl:Class	
GO:0060696	biolink:NamedThing	regulation of phospholipid catabolic process	Any process that modulates the rate, frequency, or extent of phospholipid catabolism, the chemical reactions and pathways resulting in the breakdown of phospholipids, any lipid containing phosphoric acid as a mono- or diester.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-06-08T02:25:45Z					biological_process											owl:Class	
GO:0090207	biolink:NamedThing	regulation of triglyceride metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving triglyceride, any triester of glycerol.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-12-23T10:35:06Z					biological_process											owl:Class	
GO:0021875	biolink:NamedThing	fibroblast growth factor receptor signaling pathway involved in forebrain neuroblast division	The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands that contributes to the self renewal of neuroblasts in the forebrain.	tmpzr1t_l9r_go_relaxed.owl	fibroblast growth factor receptor signalling pathway in forebrain neuroblast division													biological_process											owl:Class	
GO:1990610	biolink:NamedThing	acetolactate synthase regulator activity	Binds to and modulates the activity of acetolactate synthase.	tmpzr1t_l9r_go_relaxed.owl								vw	2015-01-20T12:54:43Z					molecular_function											owl:Class	
GO:0018604	biolink:NamedThing	4-aminobenzoate 3,4-dioxygenase (deaminating) activity	Catalysis of the reaction: 4-aminobenzoate + 2 H+ + O2 + 2 e- = NH3 + 3,4-dihydroxybenzoate.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0566|EC:1.14.12.-									molecular_function											owl:Class	
GO:0055014	biolink:NamedThing	atrial cardiac muscle cell development	The process whose specific outcome is the progression of an atrial cardiac muscle cell over time, from its formation to the mature state. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction. The atrium is the part of the heart that receives blood into the organ.	tmpzr1t_l9r_go_relaxed.owl	atrial cardiomyocyte development|atrial heart muscle development													biological_process											owl:Class	
GO:0090445	biolink:NamedThing	positive regulation of nematode larval development, heterochronic	Any process that modulates the consistent predetermined time point at which a nematode larva progresses from an initial condition to a later condition and increases the rate at which this time point is reached.	tmpzr1t_l9r_go_relaxed.owl								tb	2012-08-24T13:24:43Z					biological_process											owl:Class	
GO:0048055	biolink:NamedThing	R2/R5 development	The process whose specific outcome is the progression of the R2 and R5 pair of photoreceptors in the eye over time, from their formation to the mature structures. R2 and R5 are paired photoreceptors that contribute to the outer rhabdomeres. An example of this process is found in Drosophila melanogaster.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0002948	biolink:NamedThing	archaeosine synthase activity	Catalysis of the reaction: L-glutamine + 7-cyano-7-carbaguanine15 in tRNA + H2O = L-glutamate + archaeine15 in tRNA.	tmpzr1t_l9r_go_relaxed.owl	ArcS|glutamine:preQ0-tRNA amidinotransferase	https://github.com/geneontology/go-ontology/issues/20486			Wikipedia:Archaeosine_synthase|RHEA:54084|EC:2.6.1.97			hjd	2014-08-11T10:33:59Z					molecular_function											owl:Class	
GO:0014012	biolink:NamedThing	peripheral nervous system axon regeneration	The regrowth of axons outside the central nervous system (outside the brain and spinal cord) following an axonal injury.	tmpzr1t_l9r_go_relaxed.owl	axon regeneration in peripheral nervous system													biological_process											owl:Class	
GO:0043115	biolink:NamedThing	precorrin-2 dehydrogenase activity	Catalysis of the reaction: NAD(+) + precorrin-2 = 2 H(+) + NADH + sirohydrochlorin.	tmpzr1t_l9r_go_relaxed.owl	Met8p|precorrin-2 oxidase activity|1,3-dimethyluroporphyrinogen III dehydrogenase activity|CysG|dihydrosirohydrochlorin dehydrogenase activity|SirC|siroheme synthase activity|precorrin-2:NAD+ oxidoreductase activity				MetaCyc:DIMETHUROPORDEHYDROG-RXN|EC:1.3.1.76|KEGG_REACTION:R03947|RHEA:15613									molecular_function											owl:Class	
GO:0070244	biolink:NamedThing	negative regulation of thymocyte apoptotic process	Any process that stops, prevents, or reduces the frequency, rate or extent of thymocyte death by apoptotic process.	tmpzr1t_l9r_go_relaxed.owl	down regulation of thymocyte apoptosis|inhibition of thymocyte apoptosis|down-regulation of thymocyte apoptosis|negative regulation of thymocyte apoptosis|negative regulation of immature T cell apoptosis|downregulation of thymocyte apoptosis					Note that a thymocyte is an immature T cell located in the thymus (CL:0000893).								biological_process											owl:Class	
GO:0097596	biolink:NamedThing	ventral disc supernumerary microtubule array	A partial left-handed spiral array of microtubules that lies generally dorsal to the main ventral disc microtubule array in Giardia species (trophozoite stage).	tmpzr1t_l9r_go_relaxed.owl	ventral disk supernumerary microtubule array|supernumerary microtubule array					Due to the asymmetric nature of the Giardia trophozoite, this term is defined spatially as the trophozoite is viewed from the dorsal side, with the two nuclei dorsal to the ventral disc, and the ventral disc toward the anterior.		pr	2014-04-03T11:25:07Z					cellular_component											owl:Class	
GO:0015828	biolink:NamedThing	tyrosine transport	The directed movement of tyrosine, 2-amino-3-(4-hydroxyphenyl)propanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	L-tyrosine transport													biological_process											owl:Class	
GO:0070030	biolink:NamedThing	alphav-beta1 integrin-osteopontin complex	A protein complex that consists of an alphav-beta1 integrin complex bound to osteopontin.	tmpzr1t_l9r_go_relaxed.owl	ITGAV-ITGB1-SPP1 complex													cellular_component											owl:Class	
GO:2000998	biolink:NamedThing	negative regulation of cellulose catabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of cellulose catabolic process.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of cellulose breakdown|negative regulation of cellulose catabolism|negative regulation of cellulose degradation							tt	2011-08-08T03:21:26Z					biological_process											owl:Class	
GO:0050677	biolink:NamedThing	positive regulation of urothelial cell proliferation	Any process that activates or increases the rate or extent of urothelial cell proliferation.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of urothelial cell proliferation|up regulation of urothelial cell proliferation|stimulation of urothelial cell proliferation|activation of urothelial cell proliferation|upregulation of urothelial cell proliferation													biological_process											owl:Class	
GO:2000941	biolink:NamedThing	positive regulation of plant-type cell wall cellulose catabolic process	Any process that activates or increases the frequency, rate or extent of plant-type cell wall cellulose catabolic process.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of plant-type cell wall polysaccharide breakdown							tt	2011-08-01T02:07:21Z					biological_process											owl:Class	
GO:0097195	biolink:NamedThing	pilomotor reflex	The reflex process in which the arrectores pilorum (hair follicle) muscles contract and cause the hair to stand erect.	tmpzr1t_l9r_go_relaxed.owl	horripilation|goosebump reflex|piloerection							pr	2011-12-01T05:08:14Z					biological_process											owl:Class	
GO:0010353	biolink:NamedThing	response to trehalose	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a trehalose stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to trehalose stimulus													biological_process											owl:Class	
GO:0048612	biolink:NamedThing	post-embryonic ectodermal digestive tract development	The process, occurring during the post-embryonic phase, whose specific outcome is the progression of the ectodermal gut over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl	post-embryonic ectodermal gut development													biological_process											owl:Class	
GO:0016296	biolink:NamedThing	palmitoyl-[acyl-carrier-protein] hydrolase activity	Catalysis of the reaction: palmitoyl-[acyl-carrier protein] + H2O = [acyl-carrier protein] + palmitate.	tmpzr1t_l9r_go_relaxed.owl	palmitoyl-[acyl-carrier protein] hydrolase activity|palmitoyl-ACP hydrolase activity				MetaCyc:RXN-9549|KEGG_REACTION:R08162|RHEA:41932|EC:3.1.2.14									molecular_function											owl:Class	
GO:0010796	biolink:NamedThing	regulation of multivesicular body size	Any process that modulates the volume of a multivesicular body, a type of late endosome in which regions of the limiting endosomal membrane invaginate to form internal vesicles.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0045029	biolink:NamedThing	G protein-coupled UDP receptor activity	Combining with a nucleotide and transmitting the signal to a heterotrimeric G-protein complex to initiate a change in cell activity, activated by UDP.	tmpzr1t_l9r_go_relaxed.owl	UDP-activated nucleotide receptor activity													molecular_function											owl:Class	
GO:1903034	biolink:NamedThing	regulation of response to wounding	Any process that modulates the frequency, rate or extent of response to wounding.	tmpzr1t_l9r_go_relaxed.owl	regulation of physiological response to wounding							kmv	2014-05-18T01:28:46Z					biological_process											owl:Class	
GO:0031072	biolink:NamedThing	heat shock protein binding	Binding to a heat shock protein, a protein synthesized or activated in response to heat shock.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0061363	biolink:NamedThing	negative regulation of progesterone biosynthesis involved in luteolysis	Any process that decreases the rate, frequency or extent of the biosynthesis of progesterone biosynthesis that contributes to luteolysis.	tmpzr1t_l9r_go_relaxed.owl	functional luteolysis							dph	2010-10-14T03:08:41Z					biological_process											owl:Class	
GO:0099065	biolink:NamedThing	integral component of spine apparatus membrane	The component of the spine apparatus membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0052318	biolink:NamedThing	regulation of phytoalexin metabolic process	Any process that modulates the frequency, rate or extent of phytoalexin metabolism, the chemical reactions and pathways involving phytoalexins, any of a range of substances produced by plants as part of their defense response.	tmpzr1t_l9r_go_relaxed.owl	regulation of phytoalexin metabolism													biological_process											owl:Class	
GO:0043497	biolink:NamedThing	regulation of protein heterodimerization activity	Any process that modulates the frequency, rate or extent of protein heterodimerization, interacting selectively with a nonidentical protein to form a heterodimer.	tmpzr1t_l9r_go_relaxed.owl						Note that protein heterodimerization is a molecular function: 'protein heterodimerization activity ; GO:0046982'.								biological_process											owl:Class	
GO:0006055	biolink:NamedThing	CMP-N-acetylneuraminate biosynthetic process	The chemical reactions and pathways resulting in the formation of CMP-N-acetylneuraminate, a substance composed of 5-(acetylamino)-3,5-dideoxy-D-glycero-D-galacto-non-3-ulosonic acid in glycosidic linkage with cytidine monophosphate.	tmpzr1t_l9r_go_relaxed.owl	CMP-N-acetylneuraminate synthesis|CMP-N-acetylneuraminate anabolism|CMP-N-acetylneuraminate biosynthesis|CMP-N-acetylneuraminate formation													biological_process											owl:Class	
GO:0031111	biolink:NamedThing	negative regulation of microtubule polymerization or depolymerization	Any process that stops, prevents, or reduces the frequency, rate or extent of microtubule polymerization or depolymerization.	tmpzr1t_l9r_go_relaxed.owl	downregulation of microtubule polymerization or depolymerization|down-regulation of microtubule polymerization or depolymerization|down regulation of microtubule polymerization or depolymerization|inhibition of microtubule polymerization or depolymerization													biological_process											owl:Class	
GO:0047974	biolink:NamedThing	guanosine deaminase activity	Catalysis of the reaction: guanosine + H2O = xanthosine + NH3.	tmpzr1t_l9r_go_relaxed.owl	guanosine aminohydrolase activity|guanosine aminase activity				EC:3.5.4.15|MetaCyc:GUANOSINE-DEAMINASE-RXN|RHEA:12861									molecular_function											owl:Class	
GO:0071758	biolink:NamedThing	IgW immunoglobulin complex	A protein complex composed of two identical immunoglobulin heavy chains of the IgW isotype and two identical immunoglobulin light chains, held together by disulfide bonds. An IgW immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.	tmpzr1t_l9r_go_relaxed.owl						Note that an IgW immunoglobulin complex has the function of antigen binding if a suitable antigen is available. Note that IgW is found in fish.		mah	2010-03-24T01:44:53Z					cellular_component											owl:Class	
GO:1904423	biolink:NamedThing	dehydrodolichyl diphosphate synthase complex	A protein complex which is capable of dehydrodolichyl diphosphate synthase activity.	tmpzr1t_l9r_go_relaxed.owl								ew	2015-07-02T19:51:40Z					cellular_component											owl:Class	
GO:0090422	biolink:NamedThing	thiamine pyrophosphate transmembrane transporter activity	Enables the transfer of thiamine pyrophosphate a substance from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	thiamine pyrophosphate transporter activity|thiamine diphosphate transporter activity				Reactome:R-HSA-8875838			tb	2012-04-17T12:28:11Z					molecular_function											owl:Class	
GO:0048617	biolink:NamedThing	embryonic foregut morphogenesis	The process in which the anatomical structures of the foregut are generated and organized, during the embryonic phase.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0006743	biolink:NamedThing	ubiquinone metabolic process	The chemical reactions and pathways involving ubiquinone, a lipid-soluble electron-transporting coenzyme.	tmpzr1t_l9r_go_relaxed.owl	coenzyme Q metabolism|ubiquinone metabolism|coenzyme Q metabolic process													biological_process											owl:Class	
GO:0070782	biolink:NamedThing	phosphatidylserine exposure on apoptotic cell surface	A phospholipid scrambling process that results in the appearance of phosphatidylserine on the outer leaflet of the plasma membrane of an apoptotic cell, which acts as an 'eat-me' signal for engulfing cells. Phosphatidylserine is exposed on the apoptotic cell surface by a phospholipid scramblase activity.	tmpzr1t_l9r_go_relaxed.owl	externalization of phosphatidylserine					In normal cells, phosphatidylserine residues are found exclusively on the inner side of the cellular membrane. During apoptosis, phosphatidylserine is transported to the outer cell surface by scramblase proteins. This event acts as an "eat-me" signal for macrophages to dispose of the dying cell. When annotating to this term, curators should be aware of the following: 1) phosphatidylserine exposure on the cell surface can occur in circumstances other than apoptosis (for example, when blood platelets are activated, they expose phosphatidylserine to trigger the clotting system, see PMID:21107324). Do not annotate to GO:0070782 unless phosphatidylserine exposure is shown to be part of an apoptotic event. 2) Caution should be applied when a study quotes annexin V assays. The annexin A5 protein binds to phosphatidylserine-containing membrane surfaces, which are usually only present on the inner leaflet of the membrane. However, in cells undergoing apoptosis, phosphatidylserine becomes exposed on the outer leaflet of the membrane. A positive annexin assay can therefore be linked to apoptotic death, but it shouldn't be confused with molecular events strictly involved in the process of phosphatidylserine exposure.		mah	2009-07-02T02:41:44Z					biological_process											owl:Class	
GO:0017121	biolink:NamedThing	plasma membrane phospholipid scrambling	The movement of a population of phospholipid molecules from one leaflet of the plasma membrane bilayer to the opposite leaflet, resulting in loss of lipid asymmetry and surface exposure of phosphatidylserine (PS) and phosphatidylethanolamine (PE).	tmpzr1t_l9r_go_relaxed.owl	phospholipid scrambling|PL scrambling					Note that this term describes the trans-bilayer motion of a population of phospholipid molecules, and should not be confused with 'phospholipid translocation ; GO:0045332'.								biological_process											owl:Class	
GO:0006875	biolink:NamedThing	cellular metal ion homeostasis	Any process involved in the maintenance of an internal steady state of metal ions at the level of a cell.	tmpzr1t_l9r_go_relaxed.owl	cellular heavy metal ion homeostasis													biological_process											owl:Class	
GO:0045960	biolink:NamedThing	positive regulation of complement activation, classical pathway	Any process that activates or increases the frequency, rate or extent of complement activation by the classical pathway.	tmpzr1t_l9r_go_relaxed.owl	activation of complement activation, classical pathway|up regulation of complement activation, classical pathway|upregulation of complement activation, classical pathway|positive regulation of complement cascade, classical pathway|stimulation of complement activation, classical pathway|up-regulation of complement activation, classical pathway													biological_process											owl:Class	
GO:1904442	biolink:NamedThing	negative regulation of thyroid gland epithelial cell proliferation	Any process that stops, prevents or reduces the frequency, rate or extent of thyroid gland epithelial cell proliferation.	tmpzr1t_l9r_go_relaxed.owl	down regulation of Hurthle cell proliferation|downregulation of Hurthle cell proliferation|inhibition of thyroid follicular cell proliferation|down-regulation of thyroid follicular cell proliferation|negative regulation of Hurthle cell proliferation|down regulation of thyroid follicular cell proliferation|negative regulation of thyroid follicular cell proliferation|down-regulation of thyroid gland epithelial cell proliferation|down regulation of thyroid gland epithelial cell proliferation|downregulation of thyroid gland epithelial cell proliferation|inhibition of Hurthle cell proliferation|down-regulation of Hurthle cell proliferation|downregulation of thyroid follicular cell proliferation|inhibition of thyroid gland epithelial cell proliferation							sl	2015-07-06T15:41:15Z					biological_process											owl:Class	
GO:0097254	biolink:NamedThing	renal tubular secretion	Secretion of substances from peritubular capillaries into the renal tubules to be incorporated subsequently into the urine. Substances that are secreted include organic anions, ammonia, potassium and drugs.	tmpzr1t_l9r_go_relaxed.owl								pr	2012-03-05T02:03:58Z					biological_process											owl:Class	
GO:1900890	biolink:NamedThing	regulation of pentadecane metabolic process	Any process that modulates the frequency, rate or extent of pentadecane metabolic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of pentadecane metabolism							tt	2012-06-13T03:05:48Z					biological_process											owl:Class	
GO:2000235	biolink:NamedThing	regulation of tRNA processing	Any process that modulates the frequency, rate or extent of tRNA processing.	tmpzr1t_l9r_go_relaxed.owl	regulation of tRNA maturation							mah	2010-11-10T12:15:08Z					biological_process											owl:Class	
GO:0038097	biolink:NamedThing	positive regulation of mast cell activation by Fc-epsilon receptor signaling pathway	An Fc-epsilon receptor signaling pathway that results in the change in morphology and behavior of a mast cell resulting from exposure to a cytokine, chemokine, soluble factor, or to (at least in mammals) an antigen which the mast cell has specifically bound via IgE bound to Fc-epsilonRI receptors.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of mast cell activation by Fc-epsilon receptor signalling pathway|Fc epsilon RI-mediated mast cell activation|Fc epsilon RI-dependent mast cell activation							bf	2012-02-16T05:30:09Z					biological_process											owl:Class	
GO:0061657	biolink:NamedThing	UFM1 conjugating enzyme activity	Isoenergetic transfer of UFM1 from one protein to another via the reaction X-UFM1 + Y -> Y-UFM1 + X, where both the X-UFM1 and Y-UFM1 linkages are thioester bonds between the C-terminal amino acid of UFM1 and a sulfhydryl side group of a cysteine residue.	tmpzr1t_l9r_go_relaxed.owl	E2							dph	2014-11-06T13:35:13Z					molecular_function											owl:Class	
GO:0061650	biolink:NamedThing	ubiquitin-like protein conjugating enzyme activity	Isoenergetic transfer of a ubiquitin-like protein (ULP) from one protein to another via the reaction X-SCP + Y -> Y-SCP + X, where both the X-SCP and Y-SCP linkages are thioester bonds between the C-terminal amino acid of SCP and a sulfhydryl side group of a cysteine residue.	tmpzr1t_l9r_go_relaxed.owl	small conjugating protein conjugating enzyme activity|E2							dph	2014-11-06T13:15:27Z					molecular_function											owl:Class	
GO:0102722	biolink:NamedThing	gamma-hydroxybutyrate dehydrogenase activity (NAD(P)-dependent	Catalysis of the reaction: 4-hydroxybutyrate + NAD(P) = 4-oxobutanoate + H+ + NAD(P)H.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-6903									molecular_function											owl:Class	
GO:0015967	biolink:NamedThing	diadenosine tetraphosphate catabolic process	The chemical reactions and pathways resulting in the breakdown of diadenosine tetraphosphate, a derivative of the nucleoside adenosine with four phosphate groups attached.	tmpzr1t_l9r_go_relaxed.owl	diadenosine tetraphosphate degradation|diadenosine tetraphosphate catabolism|diadenosine tetraphosphate breakdown													biological_process											owl:Class	
GO:0032975	biolink:NamedThing	amino acid transmembrane import into vacuole	The directed movement of amino acids into the vacuole across the vacuolar membrane.	tmpzr1t_l9r_go_relaxed.owl	vacuolar amino acid import													biological_process											owl:Class	
GO:0098886	biolink:NamedThing	modification of dendritic spine	Any process that modifies the structure of a dendritic spine.	tmpzr1t_l9r_go_relaxed.owl						This class does not cover assembly or disassembly of dendritic spines, only the modification/remodelling of existing ones.								biological_process											owl:Class	
GO:0061644	biolink:NamedThing	protein localization to CENP-A containing chromatin	Any process in which a protein is transported to, or maintained at, CENP-A containing chromatin.	tmpzr1t_l9r_go_relaxed.owl								dph	2014-08-29T12:17:05Z					biological_process											owl:Class	
GO:0071459	biolink:NamedThing	protein localization to chromosome, centromeric region	Any process in which a protein is transported to, or maintained at, the centromeric region of a chromosome.	tmpzr1t_l9r_go_relaxed.owl	protein localization to centromere|protein localization to chromosome, centric region|protein localisation to chromosome, centromeric region							mah	2009-12-17T02:11:23Z					biological_process											owl:Class	
GO:0070165	biolink:NamedThing	positive regulation of adiponectin secretion	Any process that activates or increases the frequency, rate or extent of the regulated release of adiponectin from a cell.	tmpzr1t_l9r_go_relaxed.owl	stimulation of adiponectin secretion|upregulation of adiponectin secretion|up regulation of adiponectin secretion|up-regulation of adiponectin secretion|activation of adiponectin secretion													biological_process											owl:Class	
GO:0015151	biolink:NamedThing	alpha-glucoside transmembrane transporter activity	Enables the transfer of alpha-glucosides from one side of a membrane to the other. Alpha-glucosides are glycosides in which the sugar group is a glucose residue, and the anomeric carbon of the bond is in an alpha configuration.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0034956	biolink:NamedThing	diphenyl ether 1,2-dioxygenase activity	Catalysis of the reaction: diphenyl ether + NADH + O2 + H+ = phenol + catechol + NAD+.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r1453|EC:1.13.11.-									molecular_function											owl:Class	
GO:0003987	biolink:NamedThing	acetate-CoA ligase activity	Catalysis of the reaction: ATP + acetate + CoA = AMP + diphosphate + acetyl-CoA.	tmpzr1t_l9r_go_relaxed.owl	acetyl activating enzyme|short chain fatty acyl-CoA synthetase activity|short-chain acyl-coenzyme A synthetase activity|acetic thiokinase activity|acetyl CoA ligase activity|acetate thiokinase activity|acetyl-CoA synthase activity|acetate to acetyl-CoA|acetyl coenzyme A synthetase activity|acyl-activating enzyme activity|ACS|acetyl-coenzyme A synthase activity|acetyl CoA synthase activity|acetyl-CoA synthetase activity|acetate:CoA ligase (AMP-forming)|acetyl-activating enzyme activity				Reactome:R-HSA-71735|EC:6.2.1.1|Reactome:R-HSA-449911|MetaCyc:ACETATE--COA-LIGASE-RXN|RHEA:23176|Reactome:R-HSA-8875071									molecular_function											owl:Class	
GO:0040037	biolink:NamedThing	negative regulation of fibroblast growth factor receptor signaling pathway	Any process that stops, prevents, or reduces the frequency, rate or extent of fibroblast growth factor receptor signaling pathway activity.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of FGF receptor signaling pathway|down-regulation of fibroblast growth factor receptor signaling pathway|negative regulation of FGFR signaling pathway|negative regulation of FGF receptor signalling pathway|inhibition of fibroblast growth factor receptor signaling pathway|downregulation of fibroblast growth factor receptor signaling pathway|down regulation of fibroblast growth factor receptor signaling pathway													biological_process											owl:Class	
GO:0048204	biolink:NamedThing	vesicle targeting, inter-Golgi cisterna	The process in which vesicles are directed to specific destination membranes during transport from one Golgi cisterna to another.	tmpzr1t_l9r_go_relaxed.owl	inter-Golgi cisterna targeting													biological_process											owl:Class	
GO:1901318	biolink:NamedThing	negative regulation of flagellated sperm motility	Any process that stops, prevents or reduces the frequency, rate or extent of flagellated sperm motility.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of sperm motility|down regulation of sperm motility|down regulation of sperm movement|down-regulation of sperm movement|downregulation of sperm motility|downregulation of sperm movement|inhibition of sperm motility|inhibition of sperm movement|down-regulation of sperm motility|negative regulation of sperm movement							hjd	2012-08-22T20:50:35Z					biological_process											owl:Class	
GO:1901317	biolink:NamedThing	regulation of flagellated sperm motility	Any process that modulates the frequency, rate or extent of flagellated sperm motility.	tmpzr1t_l9r_go_relaxed.owl	regulation of sperm motility|regulation of sperm movement							hjd	2012-08-22T20:50:14Z					biological_process											owl:Class	
GO:0018922	biolink:NamedThing	iprodione metabolic process	The chemical reactions and pathways involving prodione, a colorless, odorless crystal. It is used as a dicarboximide contact fungicide to control a wide variety of crop diseases by inhibiting the germination of spores and the growth of the fungal mat (mycelium).	tmpzr1t_l9r_go_relaxed.owl	iprodione metabolism				UM-BBD_pathwayID:ipd									biological_process											owl:Class	
GO:0003025	biolink:NamedThing	regulation of systemic arterial blood pressure by baroreceptor feedback	The neural regulation of blood pressure in which baroreceptors sense the amount of stretch occurring in vessels and respond to the input via central nervous system control.	tmpzr1t_l9r_go_relaxed.owl	baroreceptor regulation of systemic arterial blood pressure													biological_process											owl:Class	
GO:1903653	biolink:NamedThing	modulation by symbiont of host cell motility	Modulation of host cell motility by a symbiont of that host.	tmpzr1t_l9r_go_relaxed.owl	regulation by symbiont of host cell motility|modulation by symbiont of host cell locomotion|modulation by symbiont of host cell movement							jl	2014-11-24T17:37:56Z					biological_process											owl:Class	
GO:0036258	biolink:NamedThing	multivesicular body assembly	The aggregation, arrangement and bonding together of a set of components to form a multivesicular body, a type of late endosome in which regions of the limiting endosomal membrane invaginate to form internal vesicles; membrane proteins that enter the internal vesicles are sequestered from the cytoplasm.	tmpzr1t_l9r_go_relaxed.owl	MVB biogenesis|MVB formation|multivesicular body biogenesis							bf	2012-06-15T01:12:24Z					biological_process											owl:Class	
GO:0016605	biolink:NamedThing	PML body	A class of nuclear body; they react against SP100 auto-antibodies (PML, promyelocytic leukemia); cells typically contain 10-30 PML bodies per nucleus; alterations in the localization of PML bodies occurs after viral infection.	tmpzr1t_l9r_go_relaxed.owl	ND10|nuclear dot|PML NB|PML nuclear body													cellular_component											owl:Class	
GO:1900898	biolink:NamedThing	positive regulation of heptadecane biosynthetic process	Any process that activates or increases the frequency, rate or extent of heptadecane biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	activation of heptadecane formation|up-regulation of heptadecane synthesis|up-regulation of heptadecane biosynthetic process|upregulation of heptadecane biosynthesis|activation of heptadecane biosynthetic process|up-regulation of heptadecane biosynthesis|up regulation of heptadecane biosynthetic process|activation of heptadecane anabolism|up regulation of heptadecane synthesis|up-regulation of heptadecane anabolism|positive regulation of heptadecane synthesis|up regulation of heptadecane anabolism|positive regulation of heptadecane formation|upregulation of heptadecane formation|upregulation of heptadecane anabolism|activation of heptadecane biosynthesis|up-regulation of heptadecane formation|activation of heptadecane synthesis|up regulation of heptadecane formation|up regulation of heptadecane biosynthesis|positive regulation of heptadecane biosynthesis|positive regulation of heptadecane anabolism|upregulation of heptadecane biosynthetic process|upregulation of heptadecane synthesis							tt	2012-06-13T03:28:10Z					biological_process											owl:Class	
GO:1901816	biolink:NamedThing	beta-zeacarotene metabolic process	The chemical reactions and pathways involving beta-zeacarotene.	tmpzr1t_l9r_go_relaxed.owl	beta-zeacarotene metabolism							yaf	2013-01-22T10:42:03Z					biological_process											owl:Class	
GO:0071249	biolink:NamedThing	cellular response to nitrate	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrate stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-12-03T03:02:06Z					biological_process											owl:Class	
GO:0021778	biolink:NamedThing	oligodendrocyte cell fate specification	The process in which a cell becomes capable of differentiating autonomously into an oligodendrocyte in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0010763	biolink:NamedThing	positive regulation of fibroblast migration	Any process that increases the rate, frequency or extent of fibroblast cell migration. Fibroblast cell migration is accomplished by extension and retraction of a pseudopodium.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of fibroblast cell migration													biological_process											owl:Class	
GO:0090710	biolink:NamedThing	phosphomevalonate decarboxylase activity	Catalysis of the reaction: ATP + (R)-mevalonate 5-phosphate = ADP + isopentenyl phosphate + CO2 + phosphate.	tmpzr1t_l9r_go_relaxed.owl								tb	2016-10-21T15:59:34Z					molecular_function											owl:Class	
GO:0035740	biolink:NamedThing	CD8-positive, alpha-beta T cell proliferation	The expansion of a CD8-positive, alpha-beta T cell population by cell division.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-03-17T02:13:54Z					biological_process											owl:Class	
GO:1990164	biolink:NamedThing	histone H2A phosphorylation	The modification of histone H2A by the addition of a phosphate group.	tmpzr1t_l9r_go_relaxed.owl								mah	2013-08-08T11:13:25Z					biological_process											owl:Class	
GO:0072584	biolink:NamedThing	caveolin-mediated endocytosis	An endocytosis process that begins when material is taken up into plasma membrane caveolae, which then pinch off to form endocytic caveolar carriers.	tmpzr1t_l9r_go_relaxed.owl	caveolae-mediated endocytosis|caveolae-dependent endocytosis|caveolin-dependent endocytosis							mah	2011-02-08T04:08:33Z					biological_process											owl:Class	
GO:0106392	biolink:NamedThing	bI3 intron splicing complex	Aprotein complex required for the splicing of intron 3 of the cytochrome b (COB) gene. In S. cerevisiae, the complex contains the maturase bI3 (which derives from one of the products of the splicing), the MRS1 cofactor and the intron 4 of the cytochrome b pre-mRNA. The two proteins stimulate the ribozyme activity of the pre-mRNA which autoctalyse a group I intron splicing.	tmpzr1t_l9r_go_relaxed.owl					Intact:EBI-16426213			hjd	2021-10-08T14:43:33Z					cellular_component											owl:Class	
GO:0008458	biolink:NamedThing	carnitine O-octanoyltransferase activity	Catalysis of the reaction: (R)-carnitine + octanoyl-CoA = (S)-octanoylcarnitine + CoA.	tmpzr1t_l9r_go_relaxed.owl	overt mitochondrial carnitine palmitoyltransferase|medium-chain/long-chain carnitine acyltransferase activity|octanoyl-CoA:L-carnitine O-octanoyltransferase activity|easily solubilized mitochondrial carnitine palmitoyltransferase|carnitine medium-chain acyltransferase activity				EC:2.3.1.137|Reactome:R-HSA-390281|MetaCyc:CARNITINE-O-OCTANOYLTRANSFERASE-RXN|KEGG_REACTION:R03779|RHEA:17177									molecular_function											owl:Class	
GO:0016406	biolink:NamedThing	carnitine O-acyltransferase activity	Catalysis of the transfer of an acyl group to an oxygen atom on the carnitine molecule.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0043517	biolink:NamedThing	positive regulation of DNA damage response, signal transduction by p53 class mediator	Any process that activates, maintains or increases the rate of the cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage.	tmpzr1t_l9r_go_relaxed.owl	activation of DNA damage response, signal transduction by p53 class mediator|upregulation of DNA damage response, signal transduction by p53 class mediator|positive regulation of p53 induced by DNA damage response|up regulation of DNA damage response, signal transduction by p53 class mediator|stimulation of DNA damage response, signal transduction by p53 class mediator|up-regulation of DNA damage response, signal transduction by p53 class mediator													biological_process											owl:Class	
GO:0055070	biolink:NamedThing	copper ion homeostasis	Any process involved in the maintenance of an internal steady state of copper ions within an organism or cell.	tmpzr1t_l9r_go_relaxed.owl	copper homeostasis													biological_process											owl:Class	
GO:0050610	biolink:NamedThing	methylarsonate reductase activity	Catalysis of the reaction: 2 glutathione + H(+) + methylarsonate = glutathione disulfide + H(2)O + methylarsonous acid.	tmpzr1t_l9r_go_relaxed.owl	glutathione:methylarsonate oxidoreductase activity|MMA(V) reductase activity				EC:1.20.4.2|UM-BBD_reactionID:r0837|Reactome:R-HSA-5696230|RHEA:15969|MetaCyc:1.20.4.2-RXN|KEGG_REACTION:R05748									molecular_function											owl:Class	
GO:0030614	biolink:NamedThing	oxidoreductase activity, acting on phosphorus or arsenic in donors, disulfide as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which a phosphorus- or arsenic-containing group acts as a hydrogen or electron donor and reduces a disulfide.	tmpzr1t_l9r_go_relaxed.owl	oxidoreductase activity, acting on phosphorus or arsenic in donors, with disulphide as acceptor				EC:1.20.4.-									molecular_function											owl:Class	
GO:0090693	biolink:NamedThing	plant organ senescence	The process that occurs in a plant organ near the end of its active life that is associated with the dismantling of cell components and membranes, and an overall decline in metabolism.	tmpzr1t_l9r_go_relaxed.owl								tb	2016-08-24T10:50:29Z					biological_process											owl:Class	
GO:0015183	biolink:NamedThing	L-aspartate transmembrane transporter activity	Enables the transfer of L-aspartate from one side of a membrane to the other. L-aspartate is the anion derived from aspartic acid.	tmpzr1t_l9r_go_relaxed.owl	glutamate/aspartate porter activity|L-aspartate transporter activity|glutamate/aspartate:sodium symporter activity													molecular_function											owl:Class	
GO:2001059	biolink:NamedThing	D-tagatose 6-phosphate catabolic process	The chemical reactions and pathways resulting in the breakdown of a D-tagatose 6-phosphate.	tmpzr1t_l9r_go_relaxed.owl	D-tagatose 6-phosphate catabolism				UniPathway:UPA00704			jl	2011-09-09T03:21:33Z					biological_process											owl:Class	
GO:0071589	biolink:NamedThing	pyridine nucleoside biosynthetic process	The chemical reactions and pathways resulting in the formation of any pyridine nucleoside, one of a family of organic molecules consisting of a pyridine base covalently bonded to a sugar, usually ribose.	tmpzr1t_l9r_go_relaxed.owl	pyridine nucleoside anabolism|pyridine nucleoside synthesis|pyridine nucleoside biosynthesis|pyridine nucleoside formation							mah	2010-01-29T11:35:30Z					biological_process											owl:Class	
GO:0018930	biolink:NamedThing	3-methylquinoline metabolic process	The chemical reactions and pathways involving 3-methylquinoline, C10H9N, an aromatic compound composed of a benzene ring and a heterocyclic N-containing ring.	tmpzr1t_l9r_go_relaxed.owl	3-methylquinoline metabolism				UM-BBD_pathwayID:mqn									biological_process											owl:Class	
GO:0050927	biolink:NamedThing	positive regulation of positive chemotaxis	Any process that activates or increases the frequency, rate or extent of the directed movement of a motile cell or organism towards a higher concentration in a concentration gradient of a specific chemical.	tmpzr1t_l9r_go_relaxed.owl	upregulation of positive chemotaxis|stimulation of positive chemotaxis|up-regulation of positive chemotaxis|up regulation of positive chemotaxis|activation of positive chemotaxis													biological_process											owl:Class	
GO:0110071	biolink:NamedThing	cellularization cleavage furrow invagination front	The base of the cellularization invagination or cleavage furrow most distal to the original multi-nucleate cell or syncytium plasma membrane.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/14543						kmv	2017-11-22T20:13:21Z					cellular_component											owl:Class	
GO:0016538	biolink:NamedThing	cyclin-dependent protein serine/threonine kinase regulator activity	Modulates the activity of a cyclin-dependent protein serine/threonine kinase, enzymes of the protein kinase family that are regulated through association with cyclins and other proteins.	tmpzr1t_l9r_go_relaxed.owl	G1/S-specific cyclin|G2/M-specific cyclin|cyclin-dependent protein kinase, intrinsic regulator activity|cyclin-dependent protein kinase regulator activity|cyclin				EC:2.7.1.-|Reactome:R-HSA-3215385							GO:0003753|GO:0003752|GO:0003751		molecular_function											owl:Class	
GO:0032347	biolink:NamedThing	regulation of aldosterone biosynthetic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of aldosterone.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0047652	biolink:NamedThing	allantoate deiminase activity	Catalysis of the reaction: allantoate + H2O + H+ = CO2 + NH3 + ureidoglycine.	tmpzr1t_l9r_go_relaxed.owl	allantoate amidohydrolase activity|allantoate amidinohydrolase (decarboxylating)				EC:3.5.3.9|RHEA:27485|MetaCyc:ALLANTOATE-DEIMINASE-RXN									molecular_function											owl:Class	
GO:0052080	biolink:NamedThing	modulation by symbiont of host innate immune response MAPK kinase signaling	Any process in which an organism modulates the frequency, rate or extent of a host MAP kinase-mediated signal transduction pathway during the host innate immune response. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	modulation by symbiont of defense-related host MAP kinase-mediated signal transduction pathway|modulation by organism of defense-related MAP kinase-mediated signal transduction pathway in other organism involved in symbiotic interaction|modulation of defense-related host mitogen activated protein kinase-mediated signal transduction pathway by organism|modulation of defense-related host MAPK-mediated signal transduction pathway by organism	https://github.com/geneontology/go-ontology/issues/19235										GO:0052277		biological_process											owl:Class	
GO:1900596	biolink:NamedThing	(+)-kotanin biosynthetic process	The chemical reactions and pathways resulting in the formation of (+)-kotanin.	tmpzr1t_l9r_go_relaxed.owl	(+)-kotanin synthesis|(+)-kotanin formation|(+)-kotanin biosynthesis|(+)-kotanin anabolism							di	2012-05-15T06:54:47Z					biological_process											owl:Class	
GO:0050285	biolink:NamedThing	sinapine esterase activity	Catalysis of the reaction: O-sinapoylcholine + H(2)O = choline + H(+) + sinapate.	tmpzr1t_l9r_go_relaxed.owl	aromatic choline esterase activity|sinapoylcholine sinapohydrolase activity				EC:3.1.1.49|RHEA:10016|KEGG_REACTION:R02381|MetaCyc:SINAPINE-ESTERASE-RXN									molecular_function											owl:Class	
GO:0051475	biolink:NamedThing	glucosylglycerol transport	The directed movement of glucosylglycerol, alpha-D-glucopyranosyl-alpha-(1,2)-glycerol, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0050965	biolink:NamedThing	detection of temperature stimulus involved in sensory perception of pain	The series of events involved in the perception of pain in which a temperature stimulus is received and converted into a molecular signal.	tmpzr1t_l9r_go_relaxed.owl	perception of pain, sensory detection of temperature stimulus|thermal nociception|sensory perception of pain, sensory detection of thermal stimulus|sensory perception of pain, sensory transduction of thermal stimulus|sensory transduction of thermal stimulus during sensory perception of pain|perception of pain, detection of temperature stimulus|perception of pain, sensory transduction of temperature stimulus|sensory detection of thermal stimulus during sensory perception of pain|sensory detection of temperature stimulus during perception of pain|sensory transduction of temperature stimulus during perception of pain													biological_process											owl:Class	
GO:0062149	biolink:NamedThing	detection of stimulus involved in sensory perception of pain	The series of events involved in the perception of pain in which a stimulus is received and converted into a molecular signal.	tmpzr1t_l9r_go_relaxed.owl								dph	2019-09-13T13:48:47Z					biological_process											owl:Class	
GO:2001270	biolink:NamedThing	regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis	Any process that modulates the frequency, rate or extent of cysteine-type endopeptidase activity involved in execution phase of apoptosis.	tmpzr1t_l9r_go_relaxed.owl	regulation of effector caspase activity							pr	2011-12-13T07:59:36Z					biological_process											owl:Class	
GO:1904342	biolink:NamedThing	negative regulation of colon smooth muscle contraction	Any process that stops, prevents or reduces the frequency, rate or extent of colon smooth muscle contraction.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of colon smooth muscle contraction|downregulation of colon smooth muscle contraction|inhibition of colon smooth muscle contraction|down regulation of colon smooth muscle contraction							sl	2015-06-11T21:17:05Z					biological_process											owl:Class	
GO:1901714	biolink:NamedThing	positive regulation of urea catabolic process	Any process that activates or increases the frequency, rate or extent of urea catabolic process.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of urea catabolism|activation of urea catabolic process|up-regulation of urea degradation|activation of urea degradation|upregulation of urea breakdown|positive regulation of urea degradation|activation of urea decomposition|up-regulation of urea decomposition|activation of urea catabolism|up regulation of urea degradation|up-regulation of urea breakdown|up regulation of urea catabolism|up-regulation of urea catabolic process|positive regulation of urea decomposition|upregulation of urea decomposition|up regulation of urea breakdown|up regulation of urea decomposition|positive regulation of urea breakdown|activation of urea breakdown|up-regulation of urea catabolism|upregulation of urea degradation|up regulation of urea catabolic process|upregulation of urea catabolic process|upregulation of urea catabolism							mcc	2012-12-19T16:12:18Z					biological_process											owl:Class	
GO:1902363	biolink:NamedThing	regulation of protein localization to spindle pole body	Any process that modulates the frequency, rate or extent of protein localization to spindle pole body.	tmpzr1t_l9r_go_relaxed.owl	regulation of protein localisation to spindle pole body							vw	2013-08-15T16:38:07Z					biological_process											owl:Class	
GO:0071870	biolink:NamedThing	cellular response to catecholamine stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a catecholamine stimulus. A catecholamine is any of a group of biogenic amines that includes 4-(2-aminoethyl)pyrocatechol [4-(2-aminoethyl)benzene-1,2-diol] and derivatives formed by substitution.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-09-13T02:54:50Z					biological_process											owl:Class	
GO:0071869	biolink:NamedThing	response to catecholamine	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a catecholamine stimulus. A catecholamine is any of a group of biogenic amines that includes 4-(2-aminoethyl)pyrocatechol [4-(2-aminoethyl)benzene-1,2-diol] and derivatives formed by substitution.	tmpzr1t_l9r_go_relaxed.owl	response to catecholamine stimulus							mah	2010-09-13T02:51:13Z					biological_process											owl:Class	
GO:0008743	biolink:NamedThing	L-threonine 3-dehydrogenase activity	Catalysis of the reaction: L-threonine + NAD(+) = L-2-amino-3-oxobutanoate + CO(2) + NADH.	tmpzr1t_l9r_go_relaxed.owl	threonine 3-dehydrogenase activity|L-threonine dehydrogenase activity|threonine dehydrogenase activity|L-threonine:NAD+ oxidoreductase activity				KEGG_REACTION:R01465|Reactome:R-HSA-6798667|MetaCyc:THREODEHYD-RXN|RHEA:13161|EC:1.1.1.103									molecular_function											owl:Class	
GO:1900028	biolink:NamedThing	negative regulation of ruffle assembly	Any process that stops, prevents or reduces the frequency, rate or extent of ruffle assembly.	tmpzr1t_l9r_go_relaxed.owl	down regulation of membrane ruffling|negative regulation of membrane ruffling|down regulation of ruffle assembly|negative regulation of membrane ruffle formation|down regulation of membrane ruffle formation							yaf	2012-01-12T05:00:53Z					biological_process											owl:Class	
GO:2001018	biolink:NamedThing	negative regulation of retrograde axon cargo transport	Any process that stops, prevents or reduces the frequency, rate or extent of retrograde axon cargo transport.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of retrograde axonal transport							kmv	2011-08-11T09:44:46Z					biological_process											owl:Class	
GO:1904178	biolink:NamedThing	negative regulation of adipose tissue development	Any process that stops, prevents or reduces the frequency, rate or extent of adipose tissue development.	tmpzr1t_l9r_go_relaxed.owl	down regulation of adipose tissue development|down-regulation of adipose tissue development|down-regulation of adipogenesis|down regulation of adipogenesis|downregulation of adipose tissue development|downregulation of adipogenesis|negative regulation of adipogenesis|inhibition of adipogenesis|inhibition of adipose tissue development							sl	2015-04-29T20:01:07Z					biological_process											owl:Class	
GO:0030035	biolink:NamedThing	microspike assembly	Formation of a microspike, a dynamic, actin-rich projection extending from the surface of a migrating animal cell.	tmpzr1t_l9r_go_relaxed.owl	microspike formation|microspike biogenesis|microspike biosynthesis					Although in some literature 'microspike' and 'filopodium' are used synonymously, in GO microspike refers to a cell projection that is distinct from a filopodium. For the assembly of filopodia, use 'filopodium assembly ; GO:0046847'.								biological_process											owl:Class	
GO:1900716	biolink:NamedThing	regulation of violaceol II biosynthetic process	Any process that modulates the frequency, rate or extent of violaceol II biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of violaceol II formation|regulation of violaceol II biosynthesis|regulation of violaceol II anabolism|regulation of violaceol II synthesis							di	2012-05-22T05:05:37Z					biological_process											owl:Class	
GO:1901386	biolink:NamedThing	negative regulation of voltage-gated calcium channel activity	Any process that stops, prevents or reduces the frequency, rate or extent of voltage-gated calcium channel activity.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of depolarization-activated voltage gated calcium channel activity|inhibition of depolarization-activated calcium channel|down regulation of voltage gated calcium channel activity|inhibition of voltage gated calcium channel activity|downregulation of voltage-gated calcium ion channel activity|down-regulation of voltage gated calcium channel activity|negative regulation of voltage-dependent calcium channel activity|downregulation of voltage-sensitive calcium channel|downregulation of depolarization-activated voltage gated calcium channel activity|inhibition of depolarization-activated voltage gated calcium channel activity|down-regulation of depolarization-activated voltage-gated calcium channel activity|down regulation of depolarization-activated calcium channel|down-regulation of voltage-dependent calcium channel activity|inhibition of depolarization-activated voltage-gated calcium channel|negative regulation of dihydropyridine-sensitive calcium channel activity|inhibition of voltage-sensitive calcium channel|negative regulation of voltage-gated calcium ion channel activity|negative regulation of voltage-sensitive calcium channel|down-regulation of voltage-sensitive calcium channel|downregulation of voltage-gated calcium channel activity|down regulation of voltage-dependent calcium channel activity|down-regulation of voltage-gated calcium ion channel activity|down regulation of depolarization-activated voltage gated calcium channel activity|down-regulation of dihydropyridine-sensitive calcium channel activity|downregulation of dihydropyridine-sensitive calcium channel activity|negative regulation of depolarization-activated voltage-gated calcium channel|downregulation of depolarization-activated voltage-gated calcium channel activity|down regulation of depolarization-activated voltage-gated calcium channel|inhibition of dihydropyridine-sensitive calcium channel activity|inhibition of voltage-dependent calcium channel activity|down-regulation of depolarization-activated voltage-gated calcium channel|inhibition of voltage-gated calcium channel activity|negative regulation of depolarization-activated calcium channel|down regulation of voltage-gated calcium ion channel activity|down regulation of voltage-sensitive calcium channel|downregulation of depolarization-activated calcium channel|downregulation of voltage-dependent calcium channel activity|down regulation of dihydropyridine-sensitive calcium channel activity|downregulation of depolarization-activated voltage-gated calcium channel|negative regulation of depolarization-activated voltage-gated calcium channel activity|negative regulation of depolarization-activated voltage gated calcium channel activity|negative regulation of voltage gated calcium channel activity|down regulation of depolarization-activated voltage-gated calcium channel activity|down-regulation of voltage-gated calcium channel activity|down regulation of voltage-gated calcium channel activity|inhibition of voltage-gated calcium ion channel activity|downregulation of voltage gated calcium channel activity|inhibition of depolarization-activated voltage-gated calcium channel activity|down-regulation of depolarization-activated calcium channel							vk	2012-10-01T10:35:15Z					biological_process											owl:Class	
GO:0019615	biolink:NamedThing	catechol catabolic process, ortho-cleavage	The chemical reactions and pathways resulting in the breakdown of catechol via the ortho-cleavage pathway, in which the catechol aromatic ring is broken between the two carbon atoms bearing hydroxyl groups.	tmpzr1t_l9r_go_relaxed.owl	catechol breakdown, ortho-cleavage|catechol degradation, ortho-cleavage				MetaCyc:CATECHOL-ORTHO-CLEAVAGE-PWY									biological_process											owl:Class	
GO:0042952	biolink:NamedThing	beta-ketoadipate pathway	A pathway of aromatic compound degradation by ortho-cleavage; one branch converts protocatechuate, derived from phenolic compounds, to beta-ketoadipate, and the other branch converts catechol, generated from various aromatic hydrocarbons, amino aromatics, and lignin monomers, also to beta-ketoadipate. Two additional steps accomplish the conversion of beta-ketoadipate to tricarboxylic acid cycle intermediates.	tmpzr1t_l9r_go_relaxed.owl	ortho-cleavage pathway													biological_process											owl:Class	
GO:0019610	biolink:NamedThing	3-hydroxyphenylacetate catabolic process	The chemical reactions and pathways resulting in the breakdown of 3-hydroxyphenylacetate, 1,3-benzenediol monoacetate, also known as resorcinol monoacetate.	tmpzr1t_l9r_go_relaxed.owl	3-hydroxyphenylacetate breakdown|3-hydroxyphenylacetate catabolism|3-hydroxyphenylacetate degradation				MetaCyc:3-HYDROXYPHENYLACETATE-DEGRADATION-PWY									biological_process											owl:Class	
GO:0050196	biolink:NamedThing	[phosphorylase] phosphatase activity	Catalysis of the reaction: [phosphorylase a] + 4 H2O = 2 [phosphorylase b] + 4 phosphate.	tmpzr1t_l9r_go_relaxed.owl	phosphorylase phosphatase activity|phosphorylase a phosphatase activity|type 1 protein phosphatase activity|glycogen phosphorylase phosphatase activity|PR-enzyme|protein phosphatase C|phosphorylase a phosphohydrolase activity				EC:3.1.3.17|MetaCyc:PHOSPHORYLASE-PHOSPHATASE-RXN									molecular_function											owl:Class	
GO:0033600	biolink:NamedThing	negative regulation of mammary gland epithelial cell proliferation	Any process that stops, prevents or reduces the rate or extent of mammary gland epithelial cell proliferation.	tmpzr1t_l9r_go_relaxed.owl	down regulation of mammary gland epithelial cell proliferation|inhibition of mammary gland epithelial cell proliferation|down-regulation of mammary gland epithelial cell proliferation|downregulation of mammary gland epithelial cell proliferation													biological_process											owl:Class	
GO:0007439	biolink:NamedThing	ectodermal digestive tract development	The process whose specific outcome is the progression of the ectodermal digestive tract over time, from its formation to the mature structure. The ectodermal digestive tract includes those portions that are derived from ectoderm.	tmpzr1t_l9r_go_relaxed.owl	ectodermal gut development													biological_process											owl:Class	
GO:1990474	biolink:NamedThing	synaptic vesicle, readily releasable pool	A synaptic vesicle belonging to the pool of vesicles that are the first to be released as a result of chemical or electrical stimulation e.g. by an action potential, have the highest presynaptic membrane fusion probability and correspond to about 1% of the total number of synaptic vesicles at a resting terminal bouton.	tmpzr1t_l9r_go_relaxed.owl	readily releasable pool of synaptic vesicles|RRP							pr	2014-09-02T09:02:41Z					cellular_component											owl:Class	
GO:0008021	biolink:NamedThing	synaptic vesicle	A secretory organelle, typically 50 nm in diameter, of presynaptic nerve terminals; accumulates in high concentrations of neurotransmitters and secretes these into the synaptic cleft by fusion with the 'active zone' of the presynaptic plasma membrane.	tmpzr1t_l9r_go_relaxed.owl	docked vesicle				NIF_Subcellular:sao1071221672|Wikipedia:Synaptic_vesicle	This term should not be confused with GO:0097547 'synaptic vesicle protein transport vesicle'. STVs and synaptic vesicles differ both functionally and morphologically. Functionally, STVs are transport vesicles that deliver synaptic vesicle proteins to synapses, while synaptic vesicles are responsible for transmitter release at synapses. Morphologically, synaptic vesicles are very homogeneous, while STVs are very heterogeneous in size and shape. STVs might be a precursor for synaptic vesicles.								cellular_component											owl:Class	
GO:0090016	biolink:NamedThing	regulation of leaflet formation	Any process that modulates the frequency, rate or extent of leaflet formation.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-07-29T11:23:48Z					biological_process											owl:Class	
GO:0036086	biolink:NamedThing	positive regulation of transcription from RNA polymerase II promoter in response to iron ion starvation	Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of deprivation of iron ions.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of transcription from RNA polymerase II promoter in response to iron deficiency							bf	2012-01-05T01:45:26Z					biological_process											owl:Class	
GO:0072666	biolink:NamedThing	establishment of protein localization to vacuole	The directed movement of a protein to a specific location in a vacuole.	tmpzr1t_l9r_go_relaxed.owl	establishment of protein localisation to vacuole							mah	2011-02-14T02:56:29Z					biological_process											owl:Class	
GO:0048764	biolink:NamedThing	trichoblast maturation	A developmental process, independent of morphogenetic (shape) change, that is required for a trichoblast cell to attain its fully functional state.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0018285	biolink:NamedThing	iron incorporation into iron-sulfur cluster via tetrakis-L-cysteinyl diiron disulfide	The incorporation of iron into a 2Fe-2S iron-sulfur cluster via tetrakis-L-cysteinyl diiron disulfide.	tmpzr1t_l9r_go_relaxed.owl	iron incorporation into iron-sulphur cluster via tetrakis-L-cysteinyl diiron disulphide				RESID:AA0137									biological_process											owl:Class	
GO:0099500	biolink:NamedThing	vesicle fusion to plasma membrane	Fusion of the membrane of a vesicle with the plasma membrane, thereby releasing its contents into the extracellular space.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0045681	biolink:NamedThing	positive regulation of R8 cell differentiation	Any process that activates or increases the frequency, rate or extent of R8 cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	upregulation of R8 differentiation|up regulation of R8 differentiation|stimulation of R8 differentiation|up-regulation of R8 differentiation|activation of R8 differentiation|positive regulation of R8 differentiation													biological_process											owl:Class	
GO:0110117	biolink:NamedThing	positive regulation of compound eye photoreceptor cell differentiation	Any process that activates or increases the frequency, rate or extent of compound eye photoreceptor cell differentiation.	tmpzr1t_l9r_go_relaxed.owl								kmv	2018-07-16T18:13:28Z					biological_process											owl:Class	
GO:1903638	biolink:NamedThing	positive regulation of protein insertion into mitochondrial outer membrane	Any process that activates or increases the frequency, rate or extent of protein insertion into mitochondrial outer membrane.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of mitochondrial outer membrane protein import|upregulation of mitochondrial outer membrane protein import|activation of mitochondrial outer membrane protein import|up-regulation of mitochondrial outer membrane protein import|positive regulation of protein import into mitochondrial outer membrane|up regulation of protein import into mitochondrial outer membrane|up regulation of protein insertion into mitochondrial outer membrane|up-regulation of protein transport into mitochondrial outer membrane|upregulation of protein insertion into mitochondrial outer membrane|activation of protein import into mitochondrial outer membrane|activation of protein insertion into mitochondrial outer membrane|positive regulation of protein transport into mitochondrial outer membrane|activation of protein transport into mitochondrial outer membrane|up regulation of mitochondrial outer membrane protein import|up regulation of protein transport into mitochondrial outer membrane|up-regulation of protein insertion into mitochondrial outer membrane|upregulation of protein import into mitochondrial outer membrane|upregulation of protein transport into mitochondrial outer membrane|up-regulation of protein import into mitochondrial outer membrane							pga	2014-11-20T15:55:01Z					biological_process											owl:Class	
GO:1903955	biolink:NamedThing	positive regulation of protein targeting to mitochondrion	Any process that activates or increases the frequency, rate or extent of protein targeting to mitochondrion.	tmpzr1t_l9r_go_relaxed.owl	up regulation of protein-mitochondrial targeting|upregulation of mitochondrial translocation|positive regulation of mitochondrial protein import|positive regulation of protein-mitochondrial targeting|up regulation of mitochondrial protein import|up regulation of protein targeting to mitochondria|up-regulation of protein targeting to mitochondria|up-regulation of mitochondrial protein import|up-regulation of protein targeting to mitochondrion|activation of protein-mitochondrial targeting|up regulation of protein targeting to mitochondrion|activation of mitochondrial translocation|positive regulation of protein import into mitochondrion|activation of protein targeting to mitochondria|positive regulation of mitochondrial translocation|up-regulation of protein-mitochondrial targeting|upregulation of protein targeting to mitochondrion|activation of protein targeting to mitochondrion|upregulation of protein-mitochondrial targeting|up-regulation of mitochondrial translocation|upregulation of protein targeting to mitochondria|up regulation of protein import into mitochondrion|activation of mitochondrial protein import|activation of protein import into mitochondrion|positive regulation of protein targeting to mitochondria|upregulation of protein import into mitochondrion|upregulation of mitochondrial protein import|up-regulation of protein import into mitochondrion|up regulation of mitochondrial translocation					An example of this is PINK1 in human (UniProt symbol Q9BXM7) in PMID:24270810 inferred from mutant phenotype.		pad	2015-02-24T16:58:21Z					biological_process											owl:Class	
GO:0006294	biolink:NamedThing	nucleotide-excision repair, preincision complex assembly	The aggregation, arrangement and bonding together of proteins on DNA to form the multiprotein complex involved in damage recognition, DNA helix unwinding, and endonucleolytic cleavage at the site of DNA damage. This assembly occurs before the phosphodiester backbone of the damaged strand is cleaved 3' and 5' of the site of DNA damage.	tmpzr1t_l9r_go_relaxed.owl	nucleotide-excision repair, preincision complex formation													biological_process											owl:Class	
GO:0030392	biolink:NamedThing	fructosamine catabolic process	The chemical reactions and pathways resulting in the breakdown of fructosamine, a fructose molecule containing an amino group in place of a hydroxyl group.	tmpzr1t_l9r_go_relaxed.owl	fructosamine catabolism|fructosamine degradation|fructosamine breakdown													biological_process											owl:Class	
GO:0048777	biolink:NamedThing	positive regulation of leucophore differentiation	Any process that activates or increases the frequency, rate or extent of leucophore differentiation.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of leucophore differentiation|activation of leucophore differentiation|stimulation of leucophore differentiation|up regulation of leucophore differentiation|upregulation of leucophore differentiation													biological_process											owl:Class	
GO:0061940	biolink:NamedThing	regulation of c-di-GMP signaling	Any process that modulates the rate frequency or extent of c-di-GMP signaling.	tmpzr1t_l9r_go_relaxed.owl								dph	2017-09-14T19:07:41Z					biological_process											owl:Class	
GO:0002943	biolink:NamedThing	tRNA dihydrouridine synthesis	The process whereby a uridine in a transfer RNA is converted to dihydrouridine.	tmpzr1t_l9r_go_relaxed.owl						Dihydrouridine is found in numerous positions within loop I, the so-called dihydrouridine loop, of many transfer RNAs. Most often found at positions 16 and 17, but also sometimes at positions 20, 20a, and 20b.		hjd	2012-11-16T16:20:37Z					biological_process											owl:Class	
GO:0051417	biolink:NamedThing	microtubule nucleation by spindle pole body	The 'de novo' formation of a microtubule, mediated by the spindle pole body.	tmpzr1t_l9r_go_relaxed.owl	microtubule nucleation by SPB|SPB-mediated microtubule nucleation|spindle pole body-mediated microtubule nucleation													biological_process											owl:Class	
GO:0051713	biolink:NamedThing	negative regulation of cytolysis in other organism	Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of the cytolysis of cells in another organism.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of cytolysis of cells of another organism|negative regulation of cytolysis of cells of another, non-host, organism|down regulation of cytolysis of cells of another organism|down-regulation of cytolysis of cells of another organism|downregulation of cytolysis of cells of another organism|inhibition of cytolysis of cells of another organism											GO:0001903		biological_process											owl:Class	
GO:0120071	biolink:NamedThing	regulation of pyloric antrum smooth muscle contraction	Any process that modulates the frequency, rate or extent of any pyloric antrum smooth muscle contraction.	tmpzr1t_l9r_go_relaxed.owl								krc	2017-06-13T23:32:39Z					biological_process											owl:Class	
GO:1990091	biolink:NamedThing	sodium-dependent self proteolysis	The sodium-dependent hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their own peptide bonds.	tmpzr1t_l9r_go_relaxed.owl								sl	2013-05-06T17:30:23Z					biological_process											owl:Class	
GO:0097264	biolink:NamedThing	self proteolysis	The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their own peptide bonds.	tmpzr1t_l9r_go_relaxed.owl	autolysis|self-proteolysis							pr	2012-03-09T12:43:24Z					biological_process											owl:Class	
GO:0002235	biolink:NamedThing	detection of unfolded protein	The series of events in which an unfolded protein stimulus is received and converted into a molecular signal.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1901339	biolink:NamedThing	regulation of store-operated calcium channel activity	Any process that modulates the frequency, rate or extent of store-operated calcium channel activity.	tmpzr1t_l9r_go_relaxed.owl								pr	2012-09-03T14:23:10Z					biological_process											owl:Class	
GO:1904184	biolink:NamedThing	positive regulation of pyruvate dehydrogenase activity	Any process that activates or increases the frequency, rate or extent of pyruvate dehydrogenase activity.	tmpzr1t_l9r_go_relaxed.owl	upregulation of pyruvic acid dehydrogenase activity|activation of pyruvic acid dehydrogenase activity|positive regulation of pyruvic dehydrogenase activity|upregulation of pyruvic dehydrogenase activity|up-regulation of pyruvic dehydrogenase activity|up regulation of pyruvic dehydrogenase activity|up regulation of pyruvate dehydrogenase activity|positive regulation of pyruvic acid dehydrogenase activity|up-regulation of pyruvic acid dehydrogenase activity|up regulation of pyruvic acid dehydrogenase activity|activation of pyruvic dehydrogenase activity|activation of pyruvate dehydrogenase activity|up-regulation of pyruvate dehydrogenase activity|upregulation of pyruvate dehydrogenase activity							dph	2015-05-05T14:17:39Z					biological_process											owl:Class	
GO:0005899	biolink:NamedThing	insulin receptor complex	A disulfide-bonded, heterotetrameric receptor complex. The alpha chains are entirely extracellular, while each beta chain has one transmembrane domain. The ligand binds to the alpha subunit extracellular domain and the kinase is associated with the beta subunit intracellular domain.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0018807	biolink:NamedThing	6-hydroxycyclohex-1-ene-1-carboxyl-CoA hydratase activity	Catalysis of the reaction: 6-hydroxycyclohex-1-ene-1-carboxyl-CoA + H2O = 2,6-dihydroxycyclohexane-1-carboxyl-CoA.	tmpzr1t_l9r_go_relaxed.owl					RHEA:39651|UM-BBD_reactionID:r0204|EC:3.7.1.21									molecular_function											owl:Class	
GO:0016822	biolink:NamedThing	hydrolase activity, acting on acid carbon-carbon bonds	Catalysis of the hydrolysis of any acid carbon-carbon bond.	tmpzr1t_l9r_go_relaxed.owl					EC:3.7.-.-									molecular_function											owl:Class	
GO:0001545	biolink:NamedThing	primary ovarian follicle growth	Increase in size of primary follicles including oocyte growth and granulosa and/or theca cell proliferation until more than one layer of granulosa cells is present (preantral follicle).	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0035397	biolink:NamedThing	helper T cell enhancement of adaptive immune response	Positive regulation of an adaptive immune response mediated via cytokine production by helper T cell.	tmpzr1t_l9r_go_relaxed.owl	provision of T cell help							bf	2010-03-23T10:38:31Z					biological_process											owl:Class	
GO:0098844	biolink:NamedThing	postsynaptic endocytic zone membrane	The region of the postsynaptic membrane that is part of the postsynaptic endocytic zone.  This region of membrane is associated with stable clathrin puncta.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0042791	biolink:NamedThing	5S class rRNA transcription by RNA polymerase III	The synthesis of 5S ribosomal RNA (rRNA), or an equivalent rRNA, from a DNA template by RNA polymerase III (Pol III), originating at a type 1 RNA polymerase III promoter.	tmpzr1t_l9r_go_relaxed.owl	5S class rRNA transcription from RNA polymerase III type 1 promoter|5S rRNA transcription													biological_process											owl:Class	
GO:0009303	biolink:NamedThing	rRNA transcription	The synthesis of ribosomal RNA (rRNA), any RNA that forms part of the ribosomal structure, from a DNA template.	tmpzr1t_l9r_go_relaxed.owl	rRNA synthesis|rRNA biosynthesis|rRNA biosynthetic process													biological_process											owl:Class	
GO:0070248	biolink:NamedThing	negative regulation of natural killer cell apoptotic process	Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer cell death by apoptotic process.	tmpzr1t_l9r_go_relaxed.owl	down regulation of natural killer cell apoptosis|negative regulation of NK cell apoptosis|downregulation of natural killer cell apoptosis|negative regulation of natural killer cell apoptosis|down-regulation of natural killer cell apoptosis|inhibition of natural killer cell apoptosis													biological_process											owl:Class	
GO:0070247	biolink:NamedThing	regulation of natural killer cell apoptotic process	Any process that modulates the occurrence or rate of natural killer cell death by apoptotic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of NK cell apoptosis|regulation of natural killer cell apoptosis													biological_process											owl:Class	
GO:0000900	biolink:NamedThing	translation repressor activity, mRNA regulatory element binding	Antagonizes the ribosome-mediated translation of mRNA into a polypeptide via direct binding (through a selective and non-covalent interaction) to nucleic acid.	tmpzr1t_l9r_go_relaxed.owl	translation repressor activity, nucleic acid binding	https://github.com/geneontology/go-ontology/issues/15049												molecular_function											owl:Class	
GO:0106363	biolink:NamedThing	protein-cysteine methyltransferase activity	Catalysis of the reaction: L-cysteinyl-[protein] + S-adenosyl-L-methionine = H(+) + S-adenosyl-L-homocysteine + S-methyl-L-cysteinyl-[protein].	tmpzr1t_l9r_go_relaxed.owl					RHEA:66544			hjd	2021-02-05T15:44:58Z					molecular_function											owl:Class	
GO:1905521	biolink:NamedThing	regulation of macrophage migration	Any process that modulates the frequency, rate or extent of macrophage migration.	tmpzr1t_l9r_go_relaxed.owl								sl	2016-10-03T15:29:06Z					biological_process											owl:Class	
GO:0002685	biolink:NamedThing	regulation of leukocyte migration	Any process that modulates the frequency, rate, or extent of leukocyte migration.	tmpzr1t_l9r_go_relaxed.owl	regulation of leucocyte migration|regulation of immune cell migration													biological_process											owl:Class	
GO:1901185	biolink:NamedThing	negative regulation of ERBB signaling pathway	Any process that stops, prevents or reduces the frequency, rate or extent of ERBB signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	downregulation of ERBB signaling pathway|down regulation of ErbB signaling|downregulation of EGF receptor family signaling pathway|inhibition of ERBB signalling pathway|down-regulation of ErbB signaling|inhibition of ErbB signaling|down-regulation of ERBB signalling pathway|down-regulation of ERBB signaling pathway|negative regulation of ErbB signaling|down regulation of ERBB signaling pathway|inhibition of ERBB signaling pathway|down regulation of EGFR family signaling pathway|inhibition of EGF receptor family signaling pathway|downregulation of EGFR family signaling pathway|inhibition of EGFR family signaling pathway|negative regulation of EGFR family signaling pathway|down regulation of EGF receptor family signaling pathway|down regulation of ERBB signalling pathway|down-regulation of EGF receptor family signaling pathway|negative regulation of EGF receptor family signaling pathway|downregulation of ERBB signalling pathway|negative regulation of ERBB signalling pathway|down-regulation of EGFR family signaling pathway|downregulation of ErbB signaling							rl	2012-07-24T07:37:35Z					biological_process											owl:Class	
GO:0010701	biolink:NamedThing	positive regulation of norepinephrine secretion	Any process that increases the frequency, rate or extent of the regulated release of norepinephrine.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0014061	biolink:NamedThing	regulation of norepinephrine secretion	Any process that modulates the frequency, rate or extent of the regulated release of norepinephrine.	tmpzr1t_l9r_go_relaxed.owl	regulation of noradrenaline secretion													biological_process											owl:Class	
GO:0008478	biolink:NamedThing	pyridoxal kinase activity	Catalysis of the reaction: ATP + pyridoxal = ADP + pyridoxal 5'-phosphate.	tmpzr1t_l9r_go_relaxed.owl	pyridoxal 5-phosphate-kinase activity|pyridoxine kinase activity|pyridoxamine kinase activity|pyridoxal phosphokinase activity|pyridoxal kinase (phosphorylating)|ATP:pyridoxal 5'-phosphotransferase activity|vitamin B(6) kinase activity|vitamin B6 kinase activity				RHEA:10224|Reactome:R-HSA-964970|Reactome:R-HSA-964958|EC:2.7.1.35|MetaCyc:PYRIDOXKIN-RXN|Reactome:R-HSA-964962									molecular_function											owl:Class	
GO:0032378	biolink:NamedThing	negative regulation of intracellular lipid transport	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of lipids within cells.	tmpzr1t_l9r_go_relaxed.owl	downregulation of intracellular lipid transport|down regulation of intracellular lipid transport|inhibition of intracellular lipid transport|down-regulation of intracellular lipid transport													biological_process											owl:Class	
GO:0102275	biolink:NamedThing	cysteine-S-conjugate N-malonyl transferase activity	Catalysis of the reaction: malonyl-CoA(5-) + an L-cysteine-S-conjugate <=> coenzyme A + H+ + an N-malonyl-L-cysteine-S-conjugate.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-12534									molecular_function											owl:Class	
GO:0010713	biolink:NamedThing	negative regulation of collagen metabolic process	Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the metabolism of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0034819	biolink:NamedThing	3-HSA hydroxylase activity	Catalysis of the reaction: 3-hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione + NADPH + H+ + O2 = 3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione + NADP+ + H2O.	tmpzr1t_l9r_go_relaxed.owl					EC:1.14.13.-|UM-BBD_reactionID:r1150									molecular_function											owl:Class	
GO:0033584	biolink:NamedThing	tyrosine biosynthetic process from chorismate via L-arogenate	The chemical reactions and pathways resulting in the formation of tyrosine from other compounds, including chorismate, via the intermediate L-arogenate.	tmpzr1t_l9r_go_relaxed.owl	tyrosine synthesis from chorismate via L-arogenate|tyrosine formation from chorismate via L-arogenate|tyrosine anabolism from chorismate via L-arogenate				MetaCyc:PWY-3461									biological_process											owl:Class	
GO:1904421	biolink:NamedThing	response to D-galactosamine	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a D-galactosamine stimulus.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-07-02T15:38:20Z					biological_process											owl:Class	
GO:1901829	biolink:NamedThing	zeaxanthin bis(beta-D-glucoside) catabolic process	The chemical reactions and pathways resulting in the breakdown of zeaxanthin bis(beta-D-glucoside).	tmpzr1t_l9r_go_relaxed.owl	zeaxanthin diglucoside degradation|zeaxanthin diglucoside breakdown|zeaxanthin diglucoside catabolism|zeaxanthin bis(beta-D-glucoside) degradation|zeaxanthin bis(beta-D-glucoside) breakdown|zeaxanthin bis(beta-D-glucoside) catabolism							yaf	2013-01-22T12:32:06Z					biological_process											owl:Class	
GO:1901805	biolink:NamedThing	beta-glucoside catabolic process	The chemical reactions and pathways resulting in the breakdown of beta-glucoside.	tmpzr1t_l9r_go_relaxed.owl	beta-glucoside breakdown|beta-glucoside degradation|beta-glucoside catabolism							yaf	2013-01-22T10:10:26Z					biological_process											owl:Class	
GO:0046550	biolink:NamedThing	(3-aminopropyl)(L-aspartyl-1-amino)phosphoryl-5'-adenosine biosynthetic process from asparagine	The modification of asparagine to (3-aminopropyl)(L-aspartyl-1-amino)phosphoryl-5'-adenosine as found in microcin C7 produced from the mccA gene in E. coli plasmid pMccC7.	tmpzr1t_l9r_go_relaxed.owl	(3-aminopropyl)(L-aspartyl-1-amino)phosphoryl-5'-adenosine anabolism from asparagine|(3-aminopropyl)(L-aspartyl-1-amino)phosphoryl-5'-adenosine formation from asparagine|(3-aminopropyl)(L-aspartyl-1-amino)phosphoryl-5'-adenosine synthesis from asparagine				RESID:AA0328									biological_process											owl:Class	
GO:0102822	biolink:NamedThing	quercetin 3'-O-methyltransferase activity	Catalysis of the reaction: quercetin-7-olate + S-adenosyl-L-methionine  = H+ + isorhamnetin + S-adenosyl-L-homocysteine.	tmpzr1t_l9r_go_relaxed.owl					EC:2.1.1.42|RHEA:55332|MetaCyc:RXN-8262									molecular_function											owl:Class	
GO:1990880	biolink:NamedThing	cellular detoxification of copper ion	Any process that reduces or removes the toxicity of copper ions in a cell. These include transport of copper cations away from sensitive areas and to compartments or complexes whose purpose is sequestration.	tmpzr1t_l9r_go_relaxed.owl								al	2015-10-21T14:34:40Z					biological_process											owl:Class	
GO:0010273	biolink:NamedThing	detoxification of copper ion	Any process that reduces or removes the toxicity of copper ion. These include transport of copper away from sensitive areas and to compartments or complexes whose purpose is sequestration of copper ion.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1990818	biolink:NamedThing	L-arginine transmembrane export from vacuole	The directed movement of L-arginine out of the vacuole, across the vacuolar membrane.	tmpzr1t_l9r_go_relaxed.owl								vw	2015-08-06T15:06:33Z					biological_process											owl:Class	
GO:0007086	biolink:NamedThing	vesicle fusion with nuclear membrane involved in mitotic nuclear envelope reassembly	The cell cycle process that results in the joining of the lipid bilayer membrane around a vesicle with the lipid bilayer membrane around the nucleus, and contributes to mitotic nuclear envelope reassembly.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0000740	biolink:NamedThing	nuclear membrane fusion	The joining of 2 or more lipid bilayer membranes that surround the nucleus.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0051870	biolink:NamedThing	methotrexate binding	Binding to methotrexate, an antineoplastic antimetabolite with immunosuppressant properties. It is an inhibitor of tetrahydrofolate reductase and prevents the formation of tetrahydrofolate, necessary for synthesis of thymidylate, an essential component of DNA.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0045180	biolink:NamedThing	basal cortex	The region that lies just beneath the plasma membrane on the basal edge of a cell.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0001791	biolink:NamedThing	IgM binding	Binding to an immunoglobulin of the IgM isotype.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0019865	biolink:NamedThing	immunoglobulin binding	Binding to an immunoglobulin.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0008455	biolink:NamedThing	alpha-1,6-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity	Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + alpha-D-mannosyl-1,6-(N-acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,3)-beta-D-mannosyl-R = UDP + N-acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,6-(N-acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,3)-beta-D-mannosyl-R.	tmpzr1t_l9r_go_relaxed.owl	uridine diphosphoacetylglucosamine-alpha-1,6-mannosylglycoprotein beta-1,2-N-acetylglucosaminyltransferase activity|alpha-1,6-mannosylglycoprotein beta-1,2-N-acetylglucosaminyltransferase activity|alpha-1,6-mannosyl-glycoprotein beta-1,2-N-acetylglucosaminyltransferase activity|UDP-N-acetyl-D-glucosamine:6-(alpha-D-mannosyl)-beta-D-mannosyl-glycoprotein 2-beta-N-acetyl-D-glucosaminyltransferase activity|uridine diphosphoacetylglucosamine-alpha-D-mannoside beta-1,2-acetylglucosaminyltransferase activity|acetylglucosaminyltransferase II activity|uridine diphosphoacetylglucosamine-alpha-D-mannoside beta(1,2)-acetylglucosaminyltransferase activity|UDP-GlcNAc:mannoside alpha-(1,6) acetylglucosaminyltransferase activity|UDP-GlcNAc:mannoside alpha-1,6 acetylglucosaminyltransferase activity|alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase activity|uridine diphosphoacetylglucosamine-mannoside alpha(1,6)-acetylglucosaminyltransferase activity|N-acetylglucosaminyltransferase II activity|uridine diphosphoacetylglucosamine-mannoside alpha-1,6-acetylglucosaminyltransferase activity|GnTII activity|N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase II activity				Reactome:R-HSA-975829|EC:2.4.1.143|RHEA:12941|Reactome:R-HSA-4793955|MetaCyc:2.4.1.143-RXN|Reactome:R-HSA-9694656									molecular_function											owl:Class	
GO:0080114	biolink:NamedThing	positive regulation of glycine hydroxymethyltransferase activity	Any process that activates or increases the frequency, rate or extent of glycine hydroxymethyltransferase activity, the catalysis of the reaction 5,10-methylenetetrahydrofolate + glycine + H2O = tetrahydrofolate + L-serine.	tmpzr1t_l9r_go_relaxed.owl								dhl	2009-04-27T03:27:15Z					biological_process											owl:Class	
GO:0140404	biolink:NamedThing	effector-mediated modulation of host innate immune response by symbiont	A process mediated by a molecule secreted by a symbiont that results in the modulation (either activation or suppression) of a host innate immune response. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	effector-triggered modulation of host immune response by symbiont|effector mediated modulation of host immune response by symbiont|effector-dependent modulation of host immune response by symbiont|effector triggered modulation of host immune response by symbiont|effector-mediated modulation of host immunity							pg	2019-12-05T11:38:44Z					biological_process											owl:Class	
GO:0102417	biolink:NamedThing	apigenin-7-O-glucoside 1,6-glucosyltransferase activity	Catalysis of the reaction: apigenin 7-O-beta-D-glucoside + UDP-alpha-D-glucose <=> apigenin-7-O-gentiobioside + UDP + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-13800									molecular_function											owl:Class	
GO:1904139	biolink:NamedThing	regulation of microglial cell migration	Any process that modulates the frequency, rate or extent of microglial cell migration.	tmpzr1t_l9r_go_relaxed.owl								nc	2015-04-13T09:06:57Z					biological_process											owl:Class	
GO:0140613	biolink:NamedThing	P-type manganese transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Mn2+(in) = ADP + H+ + Mn2+(out) + phosphate.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/20918			RHEA:66820			pg	2021-03-03T22:11:36Z					molecular_function											owl:Class	
GO:0047395	biolink:NamedThing	glycerophosphoinositol glycerophosphodiesterase activity	Catalysis of the reaction: 1-(sn-glycero-3-phospho)-1D-myo-inositol + H(2)O = sn-glycerol 3-phosphate + myo-inositol + H(+).	tmpzr1t_l9r_go_relaxed.owl	sn-glycero(3)phosphoinositol glycerophosphohydrolase activity|1-(sn-glycero-3-phospho)-1D-myo-inositol glycerophosphohydrolase activity|sn-glycero-3-phospho-1-inositol glycerophosphohydrolase activity				Reactome:R-HSA-6813740|EC:3.1.4.44|MetaCyc:3.1.4.44-RXN|RHEA:16501|KEGG_REACTION:R01193									molecular_function											owl:Class	
GO:1902072	biolink:NamedThing	negative regulation of hypoxia-inducible factor-1alpha signaling pathway	Any process that stops, prevents or reduces the frequency, rate or extent of hypoxia-inducible factor-1alpha signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	down regulation of HIF1alpha pathway|downregulation of hypoxia-inducible factor-1alpha signalling pathway|negative regulation of hypoxia-inducible factor-1alpha signalling pathway|down-regulation of HIF1alpha pathway|down regulation of hypoxia-inducible factor-1alpha signalling pathway|down regulation of hypoxia-inducible factor-1alpha signaling pathway|inhibition of HIF1alpha pathway|down-regulation of hypoxia-inducible factor-1alpha signalling pathway|inhibition of hypoxia-inducible factor-1alpha signaling pathway|negative regulation of HIF1alpha pathway|downregulation of hypoxia-inducible factor-1alpha signaling pathway|downregulation of HIF1alpha pathway|down-regulation of hypoxia-inducible factor-1alpha signaling pathway|inhibition of hypoxia-inducible factor-1alpha signalling pathway							bf	2013-04-18T13:28:25Z					biological_process											owl:Class	
GO:0044624	biolink:NamedThing	envenomation resulting in modulation of cell migration in other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the modulation of cell migration in the bitten organism.	tmpzr1t_l9r_go_relaxed.owl	envenomation resulting in regulation of cell migration in other organism							jl	2012-07-04T05:03:56Z					biological_process											owl:Class	
GO:0046201	biolink:NamedThing	cyanate biosynthetic process	The chemical reactions and pathways resulting in the formation of cyanate, NCO-, the anion of cyanic acid.	tmpzr1t_l9r_go_relaxed.owl	cyanate synthesis|cyanate formation|cyanate biosynthesis|cyanate anabolism													biological_process											owl:Class	
GO:0019002	biolink:NamedThing	GMP binding	Binding to GMP, guanosine monophosphate.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0043743	biolink:NamedThing	LPPG:FO 2-phospho-L-lactate transferase activity	Catalysis of the reaction: 7,8-didemethyl-8-hydroxy-5-deazariboflavin + lactyl-2-diphospho-5'-guanosine = coenzyme F420-0 + GMP.	tmpzr1t_l9r_go_relaxed.owl					RHEA:27510|EC:2.7.8.28									molecular_function											owl:Class	
GO:1902941	biolink:NamedThing	regulation of voltage-gated chloride channel activity	Any process that modulates the frequency, rate or extent of voltage-gated chloride channel activity.	tmpzr1t_l9r_go_relaxed.owl	regulation of voltage gated chloride channel activity|regulation of voltage-dependent chloride channel activity							als	2014-04-28T08:55:31Z					biological_process											owl:Class	
GO:0051524	biolink:NamedThing	cell growth mode switching, bipolar to monopolar	The process in which a cell switches from bipolar cell growth to monopolar cell growth.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0060824	biolink:NamedThing	retinoic acid receptor signaling pathway involved in neural plate anterior/posterior pattern formation	The series of molecular signals generated as a consequence of a retinoic acid receptor binding to one of its physiological ligands that contributes to the formation of the anterior/posterior pattern of the neural plate.	tmpzr1t_l9r_go_relaxed.owl	retinoic acid receptor signalling pathway involved in neural plate anterior/posterior pattern formation							dph	2009-08-11T01:30:57Z					biological_process											owl:Class	
GO:0099072	biolink:NamedThing	regulation of postsynaptic membrane neurotransmitter receptor levels	Any process that regulates the the local concentration of neurotransmitter receptor at the postsynaptic membrane.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0102619	biolink:NamedThing	oryzalexin C synthase (oryzalexin A dependent) activity	Catalysis of the reaction: oryzalexin A + NAD(P) <=> oryzalexin C + H+ + NAD(P)H.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-15467									molecular_function											owl:Class	
GO:1905786	biolink:NamedThing	positive regulation of anaphase-promoting complex-dependent catabolic process	Any process that activates or increases the frequency, rate or extent of anaphase-promoting complex-dependent catabolic process.	tmpzr1t_l9r_go_relaxed.owl								vw	2017-01-09T10:16:33Z					biological_process											owl:Class	
GO:0048597	biolink:NamedThing	post-embryonic camera-type eye morphogenesis	The process in which the anatomical structures of the eye are generated and organized during post-embryonic development.	tmpzr1t_l9r_go_relaxed.owl	post-embryonic camera-style eye morphogenesis|post-embryonic eye morphogenesis													biological_process											owl:Class	
GO:0048050	biolink:NamedThing	post-embryonic eye morphogenesis	The process, occurring after embryonic development, by which the anatomical structures of the eye are generated and organized. The eye is the organ of sight.	tmpzr1t_l9r_go_relaxed.owl												GO:0048051		biological_process											owl:Class	
GO:0034561	biolink:NamedThing	1,2-bis(4-hydroxyphenyl)-2-proponol dehydratase activity	Catalysis of the reaction: 1,2-bis(4-hydroxyphenyl)-2-propanol = 4,4'-dihydroxy-alpha-methylstilbene + H2O.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0862									molecular_function											owl:Class	
GO:0140466	biolink:NamedThing	iron-sulfur cluster export from the mitochondrion	The directed movement of iron sulfur clusters from inside the mitochondrion into the cytosol by crossing the inner mitochondrial membrane.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/19504						pg	2020-05-22T10:01:36Z					biological_process											owl:Class	
GO:0044127	biolink:NamedThing	regulation of development of symbiont in host	Any process in which the symbiont regulates its progression from an initial condition to a later condition, within the cells or tissues of the host organism. This may (but not necessarily) include a filamentous growth form, and also can include secretion of proteases and lipases to break down. The host is defined as the larger of the organisms involved in the symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl						This term partially replaces the obsolete term 'regulation of growth or development of symbiont in host ; GO:0033665'. See also 'regulation of growth of symbiont in host ; GO:0044126'.		jl	2009-08-04T02:11:08Z					biological_process											owl:Class	
GO:0006230	biolink:NamedThing	TMP biosynthetic process	The chemical reactions and pathways resulting in the formation of TMP, ribosylthymine monophosphate.	tmpzr1t_l9r_go_relaxed.owl	TMP formation|TMP anabolism|TMP synthesis|TMP biosynthesis													biological_process											owl:Class	
GO:0009174	biolink:NamedThing	pyrimidine ribonucleoside monophosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of pyrimidine ribonucleoside monophosphate, a compound consisting of a pyrimidine base linked to a ribose sugar esterified with phosphate on the sugar.	tmpzr1t_l9r_go_relaxed.owl	pyrimidine ribonucleoside monophosphate biosynthesis|pyrimidine ribonucleoside monophosphate anabolism|pyrimidine ribonucleoside monophosphate formation|pyrimidine ribonucleoside monophosphate synthesis													biological_process											owl:Class	
GO:1990272	biolink:NamedThing	anti-Mullerian hormone receptor activity	Combining with anti-Mullerian hormone to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl						An example of this is Amdh2 in M. musculus, UniprotKB:Q8K592-1 in PMID:23624077.		hjd	2014-01-14T21:41:35Z					molecular_function											owl:Class	
GO:0140679	biolink:NamedThing	ABC-type sodium transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Na(in) -> ADP + phosphate + Na(out).	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/21796			TC:3.A.1.115.1|RHEA:14633|EC:7.2.2.4			pg	2021-07-08T11:22:56Z					molecular_function											owl:Class	
GO:0019976	biolink:NamedThing	interleukin-2 binding	Binding to interleukin-2.	tmpzr1t_l9r_go_relaxed.owl	IL-2 binding													molecular_function											owl:Class	
GO:0047913	biolink:NamedThing	gallate 1-beta-glucosyltransferase activity	Catalysis of the reaction: gallate + UDP-D-glucose = 1-O-galloyl-beta-D-glucose + UDP.	tmpzr1t_l9r_go_relaxed.owl	UDPglucose:gallate glucosyltransferase activity|UDPglucose:vanillate 1-O-glucosyltransferase activity|UDPglucose-vanillate 1-glucosyltransferase activity|gallate 1-b-glucosyltransferase activity|UDP-glucose-vanillate 1-glucosyltransferase activity|UDP-glucose:gallate beta-D-glucosyltransferase activity|UDPglucose:gallate beta-D-glucosyltransferase activity				RHEA:15249|EC:2.4.1.136|MetaCyc:GALLATE-1-BETA-GLUCOSYLTRANSFERASE-RXN|KEGG_REACTION:R03297									molecular_function											owl:Class	
GO:0009834	biolink:NamedThing	plant-type secondary cell wall biogenesis	A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of inextensible cellulose- and pectin-containing cell walls that are formed between the plasma membrane and primary cell wall after cell expansion is complete. An example of this is found in Arabidopsis thaliana.	tmpzr1t_l9r_go_relaxed.owl	secondary cell wall formation|secondary cell wall synthesis|secondary cell wall anabolism|secondary cell wall biogenesis|cellulose and pectin-containing secondary cell wall biogenesis|secondary cell wall biosynthetic process													biological_process											owl:Class	
GO:1905395	biolink:NamedThing	response to flavonoid	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a flavonoid stimulus.	tmpzr1t_l9r_go_relaxed.owl								sl	2016-08-24T15:00:54Z					biological_process											owl:Class	
GO:0006761	biolink:NamedThing	dihydrofolate biosynthetic process	The chemical reactions and pathways resulting in the formation of dihydrofolate, the dihydroxylated derivative of folate.	tmpzr1t_l9r_go_relaxed.owl	7,8-dihydrofolate biosynthetic process|dihydrofolate anabolism|dihydrofolate synthesis|dihydrofolate biosynthesis|dihydrofolate formation|7,8-dihydrofolate biosynthesis													biological_process											owl:Class	
GO:0009396	biolink:NamedThing	folic acid-containing compound biosynthetic process	The chemical reactions and pathways resulting in the formation of folic acid and its derivatives.	tmpzr1t_l9r_go_relaxed.owl	folic acid and derivative biosynthesis|vitamin B9 and derivative biosynthetic process|folic acid-containing compound biosynthesis|folate-containing compound biosynthetic process|vitamin M and derivative biosynthesis|folate-containing compound biosynthesis|vitamin B9 and derivative biosynthesis|folic acid-containing compound anabolism|folic acid and derivative biosynthetic process|vitamin M and derivative biosynthetic process|folate and derivative biosynthesis|folate and derivative biosynthetic process|folic acid-containing compound formation|folic acid-containing compound synthesis													biological_process											owl:Class	
GO:2000925	biolink:NamedThing	negative regulation of cellodextrin metabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of cellodextrin metabolic process.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of cellodextrin metabolism							tt	2011-08-01T12:39:56Z					biological_process											owl:Class	
GO:0060044	biolink:NamedThing	negative regulation of cardiac muscle cell proliferation	Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle cell proliferation.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of heart muscle cell proliferation													biological_process											owl:Class	
GO:0055022	biolink:NamedThing	negative regulation of cardiac muscle tissue growth	Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle growth.	tmpzr1t_l9r_go_relaxed.owl	down regulation of cardiac muscle growth|negative regulation of heart muscle growth|down-regulation of cardiac muscle growth|downregulation of cardiac muscle growth|inhibition of cardiac muscle growth													biological_process											owl:Class	
GO:0007197	biolink:NamedThing	adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway	The series of molecular signals generated as a consequence of a G protein-coupled acetylcholine receptor binding to its physiological ligand, where the pathway proceeds with inhibition of adenylyl cyclase and a subsequent decrease in the concentration of cyclic AMP (cAMP).	tmpzr1t_l9r_go_relaxed.owl	inhibition of adenylate cyclase activity by muscarinic acetylcholine receptor signaling pathway|muscarinic acetylcholine receptor, adenylate cyclase inhibiting pathway|muscarinic acetylcholine receptor, adenylyl cyclase inhibiting pathway|inhibition of adenylate cyclase activity by G-protein coupled acetylcholine receptor signaling pathway|inhibition of adenylate cyclase activity by muscarinic acetylcholine receptor signalling pathway													biological_process											owl:Class	
GO:0102586	biolink:NamedThing	cyanidin 3-O-[2''-O-(2''-O-(sinapoyl) xylosyl) 6''-O-(p-coumaroyl) glucoside] 5-O-[6''-O-(malonyl) glucoside] sinapoyltransferase activity	Catalysis of the reaction: cyanidin 3-O-[2''-O-(xylosyl)-6''-O-(p-coumaroyl) glucoside] 5-O-malonylglucoside + 1-O-sinapoyl-beta-D-glucose <=> cyanidin 3-O-[2''-O-(2''-O-(sinapoyl) xylosyl) 6'-O-(p-coumaroyl) glucoside] 5-O-[6''-O-(malonyl) glucoside + beta-D-glucose.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-15332									molecular_function											owl:Class	
GO:0102718	biolink:NamedThing	TRIBOA-glucoside methyltransferase activity	Catalysis of the reaction: TRIBOA-beta-D-glucoside + S-adenosyl-L-methionine  <=> (2R)-DIMBOA glucoside + S-adenosyl-L-homocysteine  + H+.	tmpzr1t_l9r_go_relaxed.owl					RHEA:32099|EC:2.1.1.241|MetaCyc:RXN-6687									molecular_function											owl:Class	
GO:1900821	biolink:NamedThing	orlandin biosynthetic process	The chemical reactions and pathways resulting in the formation of orlandin.	tmpzr1t_l9r_go_relaxed.owl	orlandin anabolism|orlandin synthesis|orlandin formation|orlandin biosynthesis							di	2012-06-04T10:15:24Z					biological_process											owl:Class	
GO:1902925	biolink:NamedThing	poly(hydroxyalkanoate) biosynthetic process from fatty acid	The chemical reactions and pathways resulting in the formation of poly(hydroxyalkanoate) from fatty acid.	tmpzr1t_l9r_go_relaxed.owl	poly(hydroxyalkanoate) anabolism from fatty acid|poly(hydroxyalkanoate) biosynthesis from fatty acid|poly(hydroxyalkanoate) formation from fatty acid|poly(hydroxyalkanoate) synthesis from fatty acid							tt	2014-04-21T22:53:59Z					biological_process											owl:Class	
GO:1905610	biolink:NamedThing	regulation of mRNA cap binding	Any process that modulates the frequency, rate or extent of mRNA cap binding.	tmpzr1t_l9r_go_relaxed.owl								bc	2016-10-28T11:27:28Z					biological_process											owl:Class	
GO:0060304	biolink:NamedThing	regulation of phosphatidylinositol dephosphorylation	Any process that modulates the frequency, rate or extent of the chemical reaction involving the removal of one or more phosphate groups from a phosphatidylinositol.	tmpzr1t_l9r_go_relaxed.owl	regulation of phosphoinositide dephosphorylation													biological_process											owl:Class	
GO:0090411	biolink:NamedThing	brassinosteroid binding	Binding to a brassinosteroid.	tmpzr1t_l9r_go_relaxed.owl								tb	2011-08-11T02:25:30Z					molecular_function											owl:Class	
GO:0044322	biolink:NamedThing	endoplasmic reticulum quality control compartment	A subcompartment of the endoplasmic reticulum in which proteins with improper or incorrect folding accumulate. Enzymes in this compartment direct proteins with major folding problems to translocation to the cytosol and degradation, and proteins with minor folding problems to the ER, to interact with chaperon proteins.	tmpzr1t_l9r_go_relaxed.owl	ER quality control compartment|ER-derived quality control compartment|ERQC							jl	2010-08-03T01:12:59Z					cellular_component											owl:Class	
GO:0036215	biolink:NamedThing	response to stem cell factor	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stem cell factor (SCF) stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to SCF|response to stem cell factor stimulus|response to KIT ligand|response to hematopoietic growth factor KL							bf	2012-04-27T10:26:37Z					biological_process											owl:Class	
GO:0010867	biolink:NamedThing	positive regulation of triglyceride biosynthetic process	Any process that increases the rate, frequency, or extent of triglyceride biosynthesis. Triglyceride biosynthesis is the collection of chemical reactions and pathways resulting in the formation of triglyceride, any triester of glycerol.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of triacylglycerol biosynthetic process													biological_process											owl:Class	
GO:1905340	biolink:NamedThing	regulation of protein localization to kinetochore	Any process that modulates the frequency, rate or extent of protein localization to kinetochore.	tmpzr1t_l9r_go_relaxed.owl	regulation of protein localisation to kinetochore|regulation of condensin localization to kinetochore					Q9H211 in Human in PMID:22581055		es	2016-07-27T15:26:36Z					biological_process											owl:Class	
GO:0007091	biolink:NamedThing	metaphase/anaphase transition of mitotic cell cycle	The cell cycle process in which a cell progresses from metaphase to anaphase during mitosis, triggered by the activation of the anaphase promoting complex by Cdc20/Sleepy homolog which results in the degradation of Securin.	tmpzr1t_l9r_go_relaxed.owl	mitotic metaphase/anaphase transition|metaphase/anaphase transition by anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process													biological_process											owl:Class	
GO:0044772	biolink:NamedThing	mitotic cell cycle phase transition	The cell cycle process by which a cell commits to entering the next mitotic cell cycle phase.	tmpzr1t_l9r_go_relaxed.owl								jl	2013-02-28T13:09:33Z					biological_process											owl:Class	
GO:0006890	biolink:NamedThing	retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum	The directed movement of substances from the Golgi back to the endoplasmic reticulum, mediated by vesicles bearing specific protein coats such as COPI or COG.	tmpzr1t_l9r_go_relaxed.owl	retrograde transport, Golgi to endoplasmic reticulum|retrograde transport, Golgi to ER|retrograde (Golgi to ER) transport|cis-Golgi to rough ER transport|retrograde vesicle-mediated transport, Golgi to ER|cis-Golgi to rough endoplasmic reticulum vesicle-mediated transport|cis-Golgi to rough ER vesicle-mediated transport|cis-Golgi to rough endoplasmic reticulum transport											GO:0048220		biological_process											owl:Class	
GO:1904966	biolink:NamedThing	positive regulation of vitamin E biosynthetic process	Any process that activates or increases the frequency, rate or extent of vitamin E biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of vitamin E formation|up-regulation of alpha-tocopherol biosynthesis|up-regulation of vitamin E biosynthetic process|up regulation of tocopherol biosynthesis|up-regulation of tocopherol biosynthesis|up regulation of vitamin E synthesis|activation of tocopherol biosynthetic process|up-regulation of vitamin E anabolism|activation of vitamin E formation|up regulation of tocopherol biosynthetic process|positive regulation of alpha-tocopherol biosynthesis|upregulation of vitamin E synthesis|activation of vitamin E synthesis|up-regulation of alpha-tocopherol biosynthetic process|positive regulation of vitamin E biosynthesis|upregulation of vitamin E biosynthetic process|upregulation of vitamin E biosynthesis|up regulation of alpha-tocopherol biosynthesis|upregulation of vitamin E formation|positive regulation of alpha-tocopherol biosynthetic process|up regulation of vitamin E anabolism|upregulation of tocopherol biosynthesis|up-regulation of tocopherol biosynthetic process|positive regulation of vitamin E anabolism|positive regulation of tocopherol biosynthesis|up-regulation of vitamin E synthesis|activation of vitamin E biosynthetic process|up regulation of vitamin E biosynthesis|positive regulation of tocopherol biosynthetic process|upregulation of alpha-tocopherol biosynthetic process|activation of tocopherol biosynthesis|activation of alpha-tocopherol biosynthetic process|up-regulation of vitamin E formation|activation of vitamin E biosynthesis|up regulation of alpha-tocopherol biosynthetic process|upregulation of tocopherol biosynthetic process|upregulation of alpha-tocopherol biosynthesis|activation of alpha-tocopherol biosynthesis|upregulation of vitamin E anabolism|up-regulation of vitamin E biosynthesis|up regulation of vitamin E biosynthetic process|up regulation of vitamin E formation|activation of vitamin E anabolism|positive regulation of vitamin E synthesis							tb	2016-02-12T17:57:03Z					biological_process											owl:Class	
GO:0019122	biolink:NamedThing	peptidyl-D-alanine racemization	The formation of peptidyl-D-alanine, by either racemization or from peptidyl-L-serine.	tmpzr1t_l9r_go_relaxed.owl	alanine racemization				RESID:AA0191	See also the biological process terms 'peptidyl-D-alanine racemization, direct ; GO:0019916' and 'peptidyl-D-alanine racemization via peptidyl-L-serine ; GO:0019917'.								biological_process											owl:Class	
GO:0030710	biolink:NamedThing	regulation of border follicle cell delamination	Any process that regulates the frequency, rate or extent of border cell delamination.	tmpzr1t_l9r_go_relaxed.owl	regulation of border cell delamination													biological_process											owl:Class	
GO:0032034	biolink:NamedThing	myosin II head/neck binding	Binding to the head/neck region of a myosin II heavy chain.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0008336	biolink:NamedThing	gamma-butyrobetaine dioxygenase activity	Catalysis of the reaction: 2-oxoglutarate + 4-(trimethylammonio)butanoate + O(2) = carnitine + CO(2) + succinate.	tmpzr1t_l9r_go_relaxed.owl	gamma-butyrobetaine hydroxylase activity|alpha-butyrobetaine hydroxylase activity|gamma-BBH activity|gamma-butyrobetaine,2-oxoglutarate dioxygenase activity|g-butyrobetaine dioxygenase activity|4-trimethylammoniobutanoate,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating)|butyrobetaine hydroxylase activity				Reactome:R-HSA-71261|RHEA:24028|EC:1.14.11.1|MetaCyc:1.14.11.1-RXN|KEGG_REACTION:R02397									molecular_function											owl:Class	
GO:0097638	biolink:NamedThing	L-arginine import across plasma membrane	The directed movement of L-arginine from outside of a cell, across the plasma membrane and into the cytosol.	tmpzr1t_l9r_go_relaxed.owl	arginine import|L-arginine import into cell							tb	2012-09-24T14:28:58Z			GO:0090467|GO:1902765		biological_process											owl:Class	
GO:1901415	biolink:NamedThing	positive regulation of tetrapyrrole biosynthetic process from glycine and succinyl-CoA	Any process that activates or increases the frequency, rate or extent of tetrapyrrole biosynthetic process from glycine and succinyl-CoA.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of tetrapyrrole formation from glycine and succinyl-CoA|upregulation of tetrapyrrole biosynthesis from glycine and succinyl-CoA|activation of tetrapyrrole synthesis from glycine and succinyl-CoA|up-regulation of tetrapyrrole biosynthetic process from glycine and succinyl-CoA|up regulation of tetrapyrrole anabolism from glycine and succinyl-CoA|up-regulation of tetrapyrrole anabolism from glycine and succinyl-CoA|activation of tetrapyrrole formation from glycine and succinyl-CoA|activation of tetrapyrrole anabolism from glycine and succinyl-CoA|upregulation of tetrapyrrole anabolism from glycine and succinyl-CoA|activation of tetrapyrrole biosynthesis from glycine and succinyl-CoA|up regulation of tetrapyrrole biosynthetic process from glycine and succinyl-CoA|upregulation of tetrapyrrole synthesis from glycine and succinyl-CoA|up-regulation of tetrapyrrole biosynthesis from glycine and succinyl-CoA|up regulation of tetrapyrrole formation from glycine and succinyl-CoA|positive regulation of tetrapyrrole biosynthesis from glycine and succinyl-CoA|up regulation of tetrapyrrole synthesis from glycine and succinyl-CoA|activation of tetrapyrrole biosynthetic process from glycine and succinyl-CoA|upregulation of tetrapyrrole formation from glycine and succinyl-CoA|up-regulation of tetrapyrrole synthesis from glycine and succinyl-CoA|up regulation of tetrapyrrole biosynthesis from glycine and succinyl-CoA|positive regulation of tetrapyrrole formation from glycine and succinyl-CoA|positive regulation of tetrapyrrole anabolism from glycine and succinyl-CoA|upregulation of tetrapyrrole biosynthetic process from glycine and succinyl-CoA|positive regulation of tetrapyrrole synthesis from glycine and succinyl-CoA							tt	2012-10-01T16:29:12Z					biological_process											owl:Class	
GO:0060090	biolink:NamedThing	molecular adaptor activity	The binding activity of a molecule that brings together two or more molecules through a selective, non-covalent, often stoichiometric interaction, permitting those molecules to function in a coordinated way.	tmpzr1t_l9r_go_relaxed.owl	binding, bridging|protein complex scaffold activity|protein-containing complex scaffold activity											GO:0032947		molecular_function											owl:Class	
GO:0018281	biolink:NamedThing	GSI anchor biosynthetic process via N-seryl-glycosylsphingolipidinositolethanolamine	The formation of a C-terminal peptidyl-serine ethanolamide-linked glycosylsphingolipidinositol (GSI) anchor following hydrolysis of a seryl-peptide bond in the carboxy-terminal region of a membrane-associated protein.	tmpzr1t_l9r_go_relaxed.owl	GSI anchor anabolism via N-seryl-glycosylsphingolipidinositolethanolamine|GSI anchor formation via N-seryl-glycosylsphingolipidinositolethanolamine|GSI anchor synthesis via N-seryl-glycosylsphingolipidinositolethanolamine				RESID:AA0166									biological_process											owl:Class	
GO:0019939	biolink:NamedThing	peptidyl-S-palmitoleyl-L-cysteine biosynthetic process from peptidyl-cysteine	The modification of peptidyl-cysteine to form peptidyl-S-palmitoleyl-L-cysteine specifically.	tmpzr1t_l9r_go_relaxed.owl	peptidyl-S-palmitoleyl-L-cysteine synthesis from peptidyl-cysteine|peptidyl-S-palmitoleyl-L-cysteine formation from peptidyl-cysteine|peptidyl-S-palmitoleyl-L-cysteine anabolism from peptidyl-cysteine				RESID:AA0308									biological_process											owl:Class	
GO:0045234	biolink:NamedThing	protein palmitoleylation	The covalent attachment of a palmitoleyl group to a protein.	tmpzr1t_l9r_go_relaxed.owl	protein amino acid palmitoleylation											GO:0045235		biological_process											owl:Class	
GO:0018826	biolink:NamedThing	methionine gamma-lyase activity	Catalysis of the reaction: L-methionine = methanethiol + NH3 + 2-oxobutanoate.	tmpzr1t_l9r_go_relaxed.owl	methionine dethiomethylase activity|L-methionine methanethiol-lyase (deaminating)|methioninase activity|L-methioninase activity|methionine lyase activity|L-methionine methanethiol-lyase (deaminating; 2-oxobutanoate-forming)|L-methionine gamma-lyase activity				RHEA:23800|UM-BBD_reactionID:r0432|MetaCyc:METHIONINE-GAMMA-LYASE-RXN|EC:4.4.1.11									molecular_function											owl:Class	
GO:0090030	biolink:NamedThing	regulation of steroid hormone biosynthetic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroid hormones,compounds with a 1, 2, cyclopentanoperhydrophenanthrene nucleus that act as hormones.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-08-03T10:38:27Z					biological_process											owl:Class	
GO:0032289	biolink:NamedThing	central nervous system myelin formation	The process in which the wraps of cell membrane that constitute myelin are laid down around an axon by an oligodendrocyte in the central nervous system.	tmpzr1t_l9r_go_relaxed.owl	myelin formation in central nervous system													biological_process											owl:Class	
GO:0032288	biolink:NamedThing	myelin assembly	The process in which the wraps of cell membrane that constitute myelin are laid down around an axon in the central or peripheral nervous system.	tmpzr1t_l9r_go_relaxed.owl	myelin formation													biological_process											owl:Class	
GO:0045687	biolink:NamedThing	positive regulation of glial cell differentiation	Any process that activates or increases the frequency, rate or extent of glia cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	upregulation of glial cell differentiation|up-regulation of glial cell differentiation|up regulation of glial cell differentiation|positive regulation of neuroglia differentiation|stimulation of glial cell differentiation|positive regulation of glia cell differentiation|activation of glial cell differentiation													biological_process											owl:Class	
GO:0070622	biolink:NamedThing	UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase complex	A protein complex that possesses UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity; the bovine complex contains disulfide-linked homodimers of 166- and 51-kDa subunits and two identical, noncovalently associated 56-kDa subunits.	tmpzr1t_l9r_go_relaxed.owl	UDP-N-acetylglucosamine:lysosomal-enzyme N-acetylglucosamine-1-phosphotransferase complex|N-acetylglucosamine-1-phosphotransferase complex							mah	2009-04-29T04:50:35Z					cellular_component											owl:Class	
GO:1901818	biolink:NamedThing	beta-zeacarotene biosynthetic process	The chemical reactions and pathways resulting in the formation of beta-zeacarotene.	tmpzr1t_l9r_go_relaxed.owl	beta-zeacarotene biosynthesis|beta-zeacarotene synthesis|beta-zeacarotene formation|beta-zeacarotene anabolism							yaf	2013-01-22T10:42:12Z					biological_process											owl:Class	
GO:0042281	biolink:NamedThing	dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity	Catalysis of the addition of the first glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation; the transfer of glucose from dolichyl phosphate glucose (Dol-P-Glc) on to the lipid-linked oligosaccharide Man(9)GlcNAc(2)-PP-Dol.	tmpzr1t_l9r_go_relaxed.owl	dolichyl-P-Glc:Man9GlcNAc2-PP-dolichyl glucosyltransferase activity				EC:2.4.1.267|MetaCyc:RXN-5470|RHEA:30635									molecular_function											owl:Class	
GO:0043741	biolink:NamedThing	alpha-aminoadipate acetyltransferase activity	Catalysis of the reaction: alpha-aminoadipate + acetyl-CoA = N2-acetyl-alpha-aminoadipate + coenzyme A.	tmpzr1t_l9r_go_relaxed.owl	L-2-aminoadipate N-acetyltransferase activity	https://github.com/geneontology/go-ontology/issues/18958			MetaCyc:RXN-5181							GO:0043869		molecular_function											owl:Class	
GO:0030409	biolink:NamedThing	glutamate formimidoyltransferase activity	Catalysis of the reaction: 5-formimidoyltetrahydrofolate + L-glutamate = tetrahydrofolate + N-formimidoyl-L-glutamate.	tmpzr1t_l9r_go_relaxed.owl	formimidoyltransferase activity|glutamate formiminotransferase activity|formiminotransferase activity|formiminoglutamic formiminotransferase activity|5-formimidoyltetrahydrofolate:L-glutamate N-formimidoyltransferase activity|formiminoglutamic acid transferase activity|glutamate formyltransferase activity	https://github.com/geneontology/go-ontology/issues/20486			RHEA:15097|EC:2.1.2.5|MetaCyc:GLUTAMATE-FORMIMINOTRANSFERASE-RXN							GO:0030407		molecular_function											owl:Class	
GO:0070430	biolink:NamedThing	positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway	Any process that activates or increases the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing 1 (NOD1) pathway.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of NOD1 signaling pathway|positive regulation of nucleotide-binding oligomerization domain containing 1 signalling pathway													biological_process											owl:Class	
GO:0070428	biolink:NamedThing	regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway	Any process that modulates the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing 1 (NOD1) pathway.	tmpzr1t_l9r_go_relaxed.owl	regulation of NOD1 signaling pathway|regulation of nucleotide-binding oligomerization domain containing 1 signalling pathway													biological_process											owl:Class	
GO:1901447	biolink:NamedThing	positive regulation of response to propan-1-ol	Any process that activates or increases the frequency, rate or extent of response to propan-1-ol.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of response to propan-1-ol|up regulation of response to propan-1-ol|activation of response to propan-1-ol|upregulation of response to propan-1-ol							tt	2012-10-02T14:14:10Z					biological_process											owl:Class	
GO:1904458	biolink:NamedThing	regulation of substance P secretion	Any process that modulates the frequency, rate or extent of substance P secretion.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-07-09T19:32:50Z					biological_process											owl:Class	
GO:1903602	biolink:NamedThing	thermospermine catabolic process	The chemical reactions and pathways resulting in the breakdown of thermospermine.	tmpzr1t_l9r_go_relaxed.owl	thermospermine degradation|thermospermine catabolism|thermospermine breakdown							tb	2014-11-12T18:48:04Z					biological_process											owl:Class	
GO:1903601	biolink:NamedThing	thermospermine metabolic process	The chemical reactions and pathways involving thermospermine.	tmpzr1t_l9r_go_relaxed.owl	thermospermine metabolism							tb	2014-11-12T18:47:55Z					biological_process											owl:Class	
GO:0070674	biolink:NamedThing	hypoxanthine dehydrogenase activity	Catalysis of the reaction: hypoxanthine + NAD+ + H2O = xanthine + NADH + H+.	tmpzr1t_l9r_go_relaxed.owl	NAD-hypoxanthine dehydrogenase activity|hypoxanthine/NAD+ oxidoreductase activity|hypoxanthine/NAD(+) oxidoreductase activity|hypoxanthine:NAD+ oxidoreductase activity|hypoxanthine oxidoreductase activity|hypoxanthine-NAD oxidoreductase activity							mah	2009-05-29T01:02:13Z					molecular_function											owl:Class	
GO:0071097	biolink:NamedThing	alphaV-beta3 integrin-paxillin-Pyk2 complex	A protein complex that consists of an alphaV-beta3 integrin complex bound to paxillin and the FAK-related kinase Pyk2.	tmpzr1t_l9r_go_relaxed.owl	ITGAV-ITGB3-PXN-PTK2b complex							mah	2009-11-06T04:51:52Z					cellular_component											owl:Class	
GO:1904968	biolink:NamedThing	positive regulation of monopolar spindle attachment to meiosis I kinetochore	Any process that activates or increases the frequency, rate or extent of attachment of spindle microtubules to kinetochore involved in homologous chromosome segregation.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of attachment of spindle microtubules to kinetochore involved in homologous chromosome segregation|upregulation of sister kinetochore mono-orientation|up regulation of attachment of spindle microtubules to kinetochore involved in homologous chromosome segregation|up regulation of monopolar attachment|positive regulation of attachment of spindle microtubules to kinetochore during meiosis I|activation of monopolar attachment|upregulation of attachment of spindle microtubules to kinetochore involved in meiosis I|positive regulation of sister kinetochore mono-orientation|up-regulation of attachment of spindle microtubules to kinetochore involved in homologous chromosome segregation|activation of attachment of spindle microtubules to kinetochore involved in homologous chromosome segregation|up-regulation of attachment of spindle microtubules to kinetochore involved in meiosis I|upregulation of attachment of spindle microtubules to kinetochore involved in homologous chromosome segregation|upregulation of attachment of spindle microtubules to kinetochore during meiosis I|up regulation of attachment of spindle microtubules to kinetochore during meiosis I|up-regulation of monopolar attachment|up regulation of attachment of spindle microtubules to kinetochore involved in meiosis I|activation of sister kinetochore mono-orientation|activation of attachment of spindle microtubules to kinetochore during meiosis I|activation of attachment of spindle microtubules to kinetochore involved in meiosis I|up-regulation of sister kinetochore mono-orientation|positive regulation of monopolar attachment|up-regulation of attachment of spindle microtubules to kinetochore during meiosis I|upregulation of monopolar attachment|up regulation of sister kinetochore mono-orientation|positive regulation of attachment of spindle microtubules to kinetochore involved in meiosis I							mah	2016-02-15T15:19:20Z					biological_process											owl:Class	
GO:0046108	biolink:NamedThing	uridine metabolic process	The chemical reactions and pathways involving uridine, uracil riboside, a ribonucleoside very widely distributed but occurring almost entirely as phosphoric esters in ribonucleotides and ribonucleic acids.	tmpzr1t_l9r_go_relaxed.owl	uridine metabolism													biological_process											owl:Class	
GO:0061289	biolink:NamedThing	Wnt signaling pathway involved in kidney development	The series of molecular signals initiated by binding of Wnt protein to a receptor on the surface of the target cell, resulting a change in cell state that contributes to the progression of the kidney over time.	tmpzr1t_l9r_go_relaxed.owl	Wnt receptor signalling pathway involved in kidney development|Wnt-activated signaling pathway involved in kidney development|Wnt receptor signaling pathway involved in kidney development							dph	2010-09-03T12:04:50Z					biological_process											owl:Class	
GO:0010427	biolink:NamedThing	abscisic acid binding	Binding to abscisic acid, a plant hormone that regulates aspects of plant growth.	tmpzr1t_l9r_go_relaxed.owl	ABA binding|abscisate binding													molecular_function											owl:Class	
GO:0048757	biolink:NamedThing	pigment granule maturation	Steps required to form a membrane-bounded organelle into a pigment granule containing pigment. Maturation is a developmental process, independent of morphogenetic (shape) change, that is required for a cell or structure to attain its fully functional state.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0021700	biolink:NamedThing	developmental maturation	A developmental process, independent of morphogenetic (shape) change, that is required for an anatomical structure, cell or cellular component to attain its fully functional state.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1905273	biolink:NamedThing	positive regulation of proton-transporting ATP synthase activity, rotational mechanism	Any process that activates or increases the frequency, rate or extent of proton-transporting ATP synthase activity, rotational mechanism.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of H+-transporting ATP synthase activity|upregulation of proton-transporting ATP synthase activity, rotational mechanism|up regulation of hydrogen ion transporting two-sector ATPase activity|up-regulation of hydrogen ion transporting two-sector ATPase activity|up-regulation of hydrogen ion transporting ATP synthase activity, rotational mechanism|up regulation of hydrogen ion translocating F-type ATPase activity|activation of hydrogen ion transporting ATP synthase activity, rotational mechanism|up-regulation of H+-transporting ATP synthase activity|up regulation of proton-transporting ATP synthase activity, rotational mechanism|up-regulation of hydrogen ion translocating F-type ATPase activity|upregulation of hydrogen ion transporting ATP synthase activity, rotational mechanism|positive regulation of hydrogen ion transporting two-sector ATPase activity|up-regulation of proton-transporting ATP synthase activity, rotational mechanism|activation of H+-transporting ATP synthase activity|positive regulation of hydrogen ion transporting ATP synthase activity, rotational mechanism|activation of hydrogen ion translocating F-type ATPase activity|up regulation of hydrogen ion transporting ATP synthase activity, rotational mechanism|upregulation of H+-transporting ATP synthase activity|upregulation of hydrogen ion transporting two-sector ATPase activity|up regulation of H+-transporting ATP synthase activity|activation of hydrogen ion transporting two-sector ATPase activity|upregulation of hydrogen ion translocating F-type ATPase activity|activation of proton-transporting ATP synthase activity, rotational mechanism|positive regulation of hydrogen ion translocating F-type ATPase activity							als	2016-06-16T12:10:05Z					biological_process											owl:Class	
GO:0002495	biolink:NamedThing	antigen processing and presentation of peptide antigen via MHC class II	The process in which an antigen-presenting cell expresses a peptide antigen on its cell surface in association with an MHC class II protein complex. The peptide antigen is typically, but not always, processed from a whole protein.	tmpzr1t_l9r_go_relaxed.owl	peptide antigen processing and presentation via MHC class II													biological_process											owl:Class	
GO:0048002	biolink:NamedThing	antigen processing and presentation of peptide antigen	The process in which an antigen-presenting cell expresses peptide antigen in association with an MHC protein complex on its cell surface, including proteolysis and transport steps for the peptide antigen both prior to and following assembly with the MHC protein complex. The peptide antigen is typically, but not always, processed from an endogenous or exogenous protein.	tmpzr1t_l9r_go_relaxed.owl	antigen presentation, peptide antigen|peptide antigen processing and presentation													biological_process											owl:Class	
GO:0039711	biolink:NamedThing	cytoplasmic helical capsid assembly	The assembly of a helical viral capsid in the cytoplasm. Occurs by assembling around the viral genome.	tmpzr1t_l9r_go_relaxed.owl								bf	2013-11-28T15:23:39Z					biological_process											owl:Class	
GO:0039709	biolink:NamedThing	cytoplasmic capsid assembly	The assembly of a virus capsid that occurs in the cytoplasm.	tmpzr1t_l9r_go_relaxed.owl					VZ:1950			bf	2013-11-28T15:12:30Z					biological_process											owl:Class	
GO:0015217	biolink:NamedThing	ADP transmembrane transporter activity	Enables the transfer of ADP, adenosine diphosphate, from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0061767	biolink:NamedThing	negative regulation of lung blood pressure	The process that decreases the force with which blood travels through the lungs.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of pulmonary blood pressure							dph	2016-04-27T11:58:55Z					biological_process											owl:Class	
GO:0014916	biolink:NamedThing	regulation of lung blood pressure	The process that modulates the force with which blood travels through the lungs. The process is controlled by a balance of processes that increase pressure and decrease pressure.	tmpzr1t_l9r_go_relaxed.owl	regulation of pulmonary blood pressure													biological_process											owl:Class	
GO:0090223	biolink:NamedThing	chromatin-templated microtubule nucleation	The 'de novo' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates from chromatin.	tmpzr1t_l9r_go_relaxed.owl								tb	2010-01-13T10:53:35Z					biological_process											owl:Class	
GO:0047214	biolink:NamedThing	cyanidin-3-rhamnosylglucoside 5-O-glucosyltransferase activity	Catalysis of the reaction: cyanidin-3-O-D-rhamnosyl-(1,6)-D-glucoside + UDP-D-glucose = cyanidin-3-O-[D-rhamnosyl-(1,6)-D-glucoside]-5-O-D-glucoside + UDP.	tmpzr1t_l9r_go_relaxed.owl	cyanidin-3-O-rutinoside 5-O-glucosyltransferase activity|UDP-glucose:cyanidin-3-O-beta-L-rhamnosyl-(1->6)-beta-D-glucoside 5-O-beta-D-glucosyltransferase activity|UDP-glucose:cyanidin-3-O-D-rhamnosyl-1,6-D-glucoside 5-O-D-glucosyltransferase activity|uridine diphosphoglucose-cyanidin 3-rhamnosylglucoside 5-O-glucosyltransferase activity				MetaCyc:2.4.1.116-RXN|EC:2.4.1.116|RHEA:12144									molecular_function											owl:Class	
GO:1904974	biolink:NamedThing	heparanase complex	A protein complex which is capable of heparanase activity.	tmpzr1t_l9r_go_relaxed.owl	HEPS complex					An example of this is HPSE in human (Q9Y251) in PMID:12927802 (inferred from direct assay).		bhm	2016-02-18T11:50:39Z					cellular_component											owl:Class	
GO:0046657	biolink:NamedThing	folic acid catabolic process	The chemical reactions and pathways resulting in the breakdown of folic acid, pteroylglutamic acid.	tmpzr1t_l9r_go_relaxed.owl	folate catabolism|folic acid catabolism|folate catabolic process|vitamin M catabolic process|folic acid degradation|vitamin M catabolism|folic acid breakdown|vitamin B9 catabolic process|vitamin B9 catabolism													biological_process											owl:Class	
GO:2000624	biolink:NamedThing	positive regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	Any process that activates or increases the frequency, rate or extent of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of nonsense-mediated mRNA decay|positive regulation of mRNA degradation, nonsense-mediated decay|positive regulation of mRNA catabolism, nonsense-mediated|positive regulation of nuclear mRNA catabolic process, nonsense-mediated decay|positive regulation of mRNA catabolic process, nonsense-mediated|positive regulation of mRNA breakdown, nonsense-mediated decay							pr	2011-04-18T03:32:49Z					biological_process											owl:Class	
GO:1904321	biolink:NamedThing	response to forskolin	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a forskolin stimulus.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-06-10T19:01:27Z					biological_process											owl:Class	
GO:0050290	biolink:NamedThing	sphingomyelin phosphodiesterase D activity	Catalysis of the reaction: H(2)O + sphingomyelin = ceramide 1-phosphate + choline + H(+).	tmpzr1t_l9r_go_relaxed.owl	sphingomyelinase D|sphingomyelin ceramide-phosphohydrolase activity				MetaCyc:SPHINGOMYELIN-PHOSPHODIESTERASE-D-RXN|KEGG_REACTION:R02542|RHEA:20984|EC:3.1.4.41									molecular_function											owl:Class	
GO:0004620	biolink:NamedThing	phospholipase activity	Catalysis of the hydrolysis of a glycerophospholipid.	tmpzr1t_l9r_go_relaxed.owl					EC:3.1.1.-|Reactome:R-HSA-6792445|Reactome:R-HSA-6786650									molecular_function											owl:Class	
GO:0060925	biolink:NamedThing	ventricular cardiac muscle cell fate commitment	The commitment of cells to ventricular cardiac muscle cell fates and their capacity to differentiate into cardiac muscle cells of the ventricle. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction.	tmpzr1t_l9r_go_relaxed.owl	ventricular cardiomyocyte cell fate commitment|ventricular heart muscle cell fate commitment							dph	2009-09-29T11:49:39Z					biological_process											owl:Class	
GO:0071340	biolink:NamedThing	skeletal muscle acetylcholine-gated channel clustering	The accumulation of acetylcholine-gated cation channels in a narrow, central region of muscle fibers, in apposition to nerve terminals.	tmpzr1t_l9r_go_relaxed.owl	skeletal muscle AChR clustering|skeletal muscle nicotinic acetylcholine receptor clustering							mah	2009-12-11T11:13:55Z					biological_process											owl:Class	
GO:0007486	biolink:NamedThing	imaginal disc-derived female genitalia development	The process whose specific outcome is the progression of the female genitalia over time, from formation as part of the genital disc to the mature structure. An example of this is found in Drosophila melanogaster.	tmpzr1t_l9r_go_relaxed.owl	female genital development													biological_process											owl:Class	
GO:0106056	biolink:NamedThing	regulation of calcineurin-mediated signaling	Any process that modulates the frequency, rate or extent of calcineurin-mediated signaling.	tmpzr1t_l9r_go_relaxed.owl								hjd	2017-09-18T16:44:05Z					biological_process											owl:Class	
GO:1904072	biolink:NamedThing	presynaptic active zone disassembly	The disaggregation of a presynaptic active zone into its constituent components.	tmpzr1t_l9r_go_relaxed.owl	pre-synaptic active zone disassembly|pre-synaptic active zone component disassembly							pr	2015-03-20T10:36:33Z					biological_process											owl:Class	
GO:0045475	biolink:NamedThing	locomotor rhythm	The rhythm of the locomotor activity of an organism during its 24 hour activity cycle.	tmpzr1t_l9r_go_relaxed.owl	circadian locomotor activity rhythm													biological_process											owl:Class	
GO:0090064	biolink:NamedThing	activation of microtubule nucleation	Any process that starts the inactive process of microtubule nucleation. Microtubule nucleation is the 'de novo' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates, some of which go on to support formation of a complete microtubule. Microtubule nucleation usually occurs from a specific site within a cell.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-08-12T11:36:15Z					biological_process											owl:Class	
GO:0030007	biolink:NamedThing	cellular potassium ion homeostasis	Any process involved in the maintenance of an internal steady state of potassium ions at the level of a cell.	tmpzr1t_l9r_go_relaxed.owl												GO:0017079		biological_process											owl:Class	
GO:1904737	biolink:NamedThing	positive regulation of fatty acid beta-oxidation using acyl-CoA dehydrogenase	Any process that activates or increases the frequency, rate or extent of fatty acid beta-oxidation using acyl-CoA dehydrogenase.	tmpzr1t_l9r_go_relaxed.owl	activation of fatty acid beta-oxidation using acyl-CoA dehydrogenase|up-regulation of fatty acid beta-oxidation using acyl-CoA dehydrogenase|upregulation of fatty acid beta-oxidation using acyl-CoA dehydrogenase|up regulation of fatty acid beta-oxidation using acyl-CoA dehydrogenase							lb	2015-10-15T08:15:03Z					biological_process											owl:Class	
GO:0008617	biolink:NamedThing	guanosine metabolic process	The chemical reactions and pathways involving guanine, guanine riboside, a nucleoside with a wide species distribution.	tmpzr1t_l9r_go_relaxed.owl	guanosine metabolism													biological_process											owl:Class	
GO:0102152	biolink:NamedThing	Delta12-linoleate epoxygenase activity	Catalysis of the reaction: H+ + 1-palmitoyl-2-linoleoyl-phosphatidylcholine + NADPH + O2 <=> 1-palmitoyl-2-vernoloyl-phosphatidylcholine + NADP + H2O.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-11671									molecular_function											owl:Class	
GO:1900441	biolink:NamedThing	negative regulation of filamentous growth of a population of unicellular organisms in response to neutral pH	Any process that stops, prevents or reduces the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to neutral pH.	tmpzr1t_l9r_go_relaxed.owl	downregulation of filamentous growth of a population of unicellular organisms in response to neutral pH|down-regulation of filamentous growth of a population of unicellular organisms in response to neutral pH|down regulation of filamentous growth of a population of unicellular organisms in response to neutral pH|inhibition of filamentous growth of a population of unicellular organisms in response to neutral pH							di	2012-04-25T05:55:57Z					biological_process											owl:Class	
GO:0006874	biolink:NamedThing	cellular calcium ion homeostasis	Any process involved in the maintenance of an internal steady state of calcium ions at the level of a cell.	tmpzr1t_l9r_go_relaxed.owl	regulation of calcium ion concentration													biological_process											owl:Class	
GO:0016942	biolink:NamedThing	insulin-like growth factor binding protein complex	A complex of proteins which includes the insulin-like growth factor (IGF) and a number of IGF-binding proteins. The complex plays a role in growth and development.	tmpzr1t_l9r_go_relaxed.owl	IGF binding protein complex													cellular_component											owl:Class	
GO:0036454	biolink:NamedThing	growth factor complex	A protein complex that has growth factor activity.	tmpzr1t_l9r_go_relaxed.owl								bf	2013-11-07T11:27:16Z					cellular_component											owl:Class	
GO:0019910	biolink:NamedThing	mitochondrial pyruvate dehydrogenase (lipoamide) phosphatase complex	A mitochondrial complex of a regulatory and catalytic subunit that catalyzes the dephosphorylation and concomitant reactivation of the alpha subunit of the E1 component of the pyruvate dehydrogenase complex. An example of this component is found in Mus musculus.	tmpzr1t_l9r_go_relaxed.owl						See also the cellular component term 'mitochondrial pyruvate dehydrogenase complex ; GO:0005967'.								cellular_component											owl:Class	
GO:0097132	biolink:NamedThing	cyclin D2-CDK6 complex	A protein complex consisting of cyclin D2 and cyclin-dependent kinase 6 (CDK6). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner.	tmpzr1t_l9r_go_relaxed.owl								pr	2011-08-01T01:56:34Z					cellular_component											owl:Class	
GO:0002313	biolink:NamedThing	mature B cell differentiation involved in immune response	The process in which a naive B cell acquires the specialized features of a mature or memory B cell during an immune response.	tmpzr1t_l9r_go_relaxed.owl	mature B lymphocyte differentiation during immune response|mature B-lymphocyte differentiation during immune response|mature B cell differentiation during immune response|mature B-cell differentiation during immune response|mature B cell development involved in immune response					Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.								biological_process											owl:Class	
GO:1903237	biolink:NamedThing	negative regulation of leukocyte tethering or rolling	Any process that stops, prevents or reduces the frequency, rate or extent of leukocyte tethering or rolling.	tmpzr1t_l9r_go_relaxed.owl	downregulation of leukocyte tethering or rolling|down regulation of leukocyte tethering or rolling|inhibition of leukocyte tethering or rolling|down-regulation of leukocyte tethering or rolling							als	2014-07-31T13:07:55Z					biological_process											owl:Class	
GO:1903236	biolink:NamedThing	regulation of leukocyte tethering or rolling	Any process that modulates the frequency, rate or extent of leukocyte tethering or rolling.	tmpzr1t_l9r_go_relaxed.owl								als	2014-07-31T13:07:48Z					biological_process											owl:Class	
GO:0036422	biolink:NamedThing	heptaprenyl diphosphate synthase activity	Catalysis of the reaction: (2E,6E)-farnesyl diphosphate + 4 isopentenyl diphosphate = 4 diphosphate + all-trans-heptaprenyl diphosphate.	tmpzr1t_l9r_go_relaxed.owl	heptaprenyl pyrophosphate synthase activity|all-trans-heptaprenyl-diphosphate synthase activity|heptaprenyl pyrophosphate synthetase activity|HepPP synthase activity				MetaCyc:TRANS-HEXAPRENYLTRANSTRANSFERASE-RXN|RHEA:27794|EC:2.5.1.30			bf	2013-09-16T11:50:41Z					molecular_function											owl:Class	
GO:0071654	biolink:NamedThing	positive regulation of chemokine (C-C motif) ligand 1 production	Any process that activates or increases the frequency, rate, or extent of production of chemokine (C-C motif) ligand 1.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of CCL1 production|positive regulation of TCA-3 production|positive regulation of T cell activation 3 production							mah	2010-02-12T10:41:14Z					biological_process											owl:Class	
GO:0071652	biolink:NamedThing	regulation of chemokine (C-C motif) ligand 1 production	Any process that modulates the frequency, rate, or extent of production of chemokine (C-C motif) ligand 1.	tmpzr1t_l9r_go_relaxed.owl	regulation of TCA-3 production|regulation of T cell activation 3 production|regulation of CCL1 production							mah	2010-02-12T10:40:19Z					biological_process											owl:Class	
GO:1903890	biolink:NamedThing	positive regulation of plant epidermal cell differentiation	Any process that activates or increases the frequency, rate or extent of plant epidermal cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	up regulation of plant epidermal cell differentiation|upregulation of plant epidermal cell differentiation|up-regulation of plant epidermal cell differentiation|activation of plant epidermal cell differentiation							tb	2015-02-06T22:30:02Z					biological_process											owl:Class	
GO:0046357	biolink:NamedThing	galactarate biosynthetic process	The chemical reactions and pathways resulting in the formation of galactarate, the anion of galactaric acid.	tmpzr1t_l9r_go_relaxed.owl	D-galactarate biosynthetic process|galactarate formation|D-galactarate biosynthesis|D-galactarate anabolism|galactarate synthesis|D-galactarate formation|galactarate biosynthesis|D-galactarate synthesis|galactarate anabolism											GO:0042872		biological_process											owl:Class	
GO:0061729	biolink:NamedThing	GDP-mannose biosynthetic process from fructose-6-phosphate	The chemical reactions and pathways resulting in the formation of GDP-mannose from fructose-6-phosphate.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-446205			dph	2015-07-24T14:50:44Z					biological_process											owl:Class	
GO:2000627	biolink:NamedThing	positive regulation of miRNA catabolic process	Any process that activates or increases the frequency, rate or extent of miRNA catabolic process.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of microRNA catabolic process							dph	2011-04-18T03:46:42Z					biological_process											owl:Class	
GO:2000630	biolink:NamedThing	positive regulation of miRNA metabolic process	Any process that activates or increases the frequency, rate or extent of miRNA metabolic process.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of microRNA metabolic process							dph	2011-04-18T03:48:01Z					biological_process											owl:Class	
GO:0000710	biolink:NamedThing	meiotic mismatch repair	A system for the identification and correction of base-base mismatches, small insertion-deletion loops, and regions of heterology that are present in duplex DNA formed with strands from two recombining molecules. Correction of the mismatch can result in non-Mendelian segregation of alleles following meiosis.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0040012	biolink:NamedThing	regulation of locomotion	Any process that modulates the frequency, rate or extent of locomotion of a cell or organism.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0061258	biolink:NamedThing	mesonephric glomerular visceral epithelial cell fate commitment	The process in which the developmental fate of a cell becomes restricted such that it will develop into a mesonephric glomerular visceral epithelial cell. A mesonephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the mesonephros.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-08-30T02:13:33Z					biological_process											owl:Class	
GO:0061251	biolink:NamedThing	mesonephric glomerular epithelial cell development	The process whose specific outcome is the progression of a mesonephric glomerular epithelial cell over time, from its formation to the mature structure. Mesonephric glomerular epithelial cells are specialized epithelial cells that form part of the mesonephric glomerulus; there are two types, mesonephric glomerular parietal epithelial cells and mesonephric glomerular visceral epithelial cells.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-08-30T01:20:45Z					biological_process											owl:Class	
GO:0042328	biolink:NamedThing	heparan sulfate N-acetylglucosaminyltransferase activity	Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + heparan sulfate = UDP + (N-acetyl-D-glucosaminyl)-heparan sulfate.	tmpzr1t_l9r_go_relaxed.owl	heparan sulphate N-acetylglucosaminyltransferase activity|heparin N-acetylglucosaminyltransferase activity													molecular_function											owl:Class	
GO:1990687	biolink:NamedThing	endoplasmic reticulum-derived vesicle fusion with endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane	The joining of the lipid bilayer membrane around an endoplasmic reticulum-derived vesicle to the lipid bilayer membrane of the ERGIC. Such vesicles include COPII-coated transport vesicles involved in anterograde transport.	tmpzr1t_l9r_go_relaxed.owl	ER-derived vesicle fusion with ERGIC membrane|ER-derived vesicle fusion with ER-Golgi intermediate compartment membrane							bhm	2015-03-12T09:31:45Z					biological_process											owl:Class	
GO:1990668	biolink:NamedThing	vesicle fusion with endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane	The joining of the lipid bilayer membrane around a vesicle to the lipid bilayer membrane of the ERGIC. This can involve anterograde or retrograde transport vesicles.	tmpzr1t_l9r_go_relaxed.owl	vesicle fusion with ER-Golgi intermediate compartment membrane|vesicle fusion with endoplasmic reticulum-Golgi intermediate compartment membrane|vesicle fusion with ERGIC membrane|vesicle fusion with ER-Golgi intermediate compartment (ERGIC) membrane							bhm	2015-03-02T11:17:32Z					biological_process											owl:Class	
GO:0140488	biolink:NamedThing	heme receptor activity	Binding specifically to heme to deliver it to a transport vesicle.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/19699						pg	2020-06-29T14:16:16Z					molecular_function											owl:Class	
GO:0070639	biolink:NamedThing	vitamin D2 metabolic process	The chemical reactions and pathways involving vitamin D2, (3S,5Z,7E,22E)-9,10-secoergosta-5,7,10(19),22-tetraen-3-ol.	tmpzr1t_l9r_go_relaxed.owl	vitamin D2 metabolism|calciferol metabolic process|ergocalciferol metabolic process							mah	2009-05-08T02:11:35Z					biological_process											owl:Class	
GO:0042359	biolink:NamedThing	vitamin D metabolic process	The chemical reactions and pathways involving vitamin D, any of a group of related, fat-soluble compounds that are derived from delta-5,7 steroids and play a central role in calcium metabolism. Specific forms of vitamin D include calciferol (ergocalciferol; vitamin D2) and cholecalciferol (calciol; vitamin D3).	tmpzr1t_l9r_go_relaxed.owl	vitamin D metabolism|cholecalciferol metabolism|ergocalciferol metabolism|calciferol metabolism|cholecalciferol metabolic process|calciferol metabolic process|ergocalciferol metabolic process													biological_process											owl:Class	
GO:0047359	biolink:NamedThing	1-alkenyl-2-acylglycerol choline phosphotransferase activity	Catalysis of the reaction: 1-alkenyl-2-acylglycerol + CDP-choline = plasmenylcholine + CMP.	tmpzr1t_l9r_go_relaxed.owl	CDP-choline:1-alkenyl-2-acylglycerol cholinephosphotransferase activity|CDP-choline-1-alkenyl-2-acyl-glycerol phosphocholinetransferase activity				EC:2.7.8.22|MetaCyc:2.7.8.22-RXN|RHEA:36227									molecular_function											owl:Class	
GO:0062036	biolink:NamedThing	sensory perception of hot stimulus	The series of events required for an organism to receive a hot temperature stimulus, convert it to a molecular signal, and recognize and characterize the signal.	tmpzr1t_l9r_go_relaxed.owl								dph	2018-04-30T13:50:47Z					biological_process											owl:Class	
GO:0106383	biolink:NamedThing	dAMP salvage	Any process which produces a dAMP from derivatives of it, without de novo synthesis.	tmpzr1t_l9r_go_relaxed.owl								hjd	2021-06-11T16:51:09Z					biological_process											owl:Class	
GO:0106381	biolink:NamedThing	purine deoxyribonucleotide salvage	Any process which produces a purine deoxyribonucleotide from derivatives of it, without de novo synthesis.	tmpzr1t_l9r_go_relaxed.owl								hjd	2021-06-11T14:55:33Z					biological_process											owl:Class	
GO:1901331	biolink:NamedThing	positive regulation of odontoblast differentiation	Any process that activates or increases the frequency, rate or extent of odontoblast differentiation.	tmpzr1t_l9r_go_relaxed.owl	upregulation of odontoblast differentiation|up regulation of odontoblast differentiation|up-regulation of odontoblast differentiation|activation of odontoblast differentiation							hjd	2012-08-31T16:50:35Z					biological_process											owl:Class	
GO:0051162	biolink:NamedThing	L-arabitol metabolic process	The chemical reactions and pathways involving L-arabitol, the pentitol derived from arabinose or lyxose by reduction of the aldehyde group.	tmpzr1t_l9r_go_relaxed.owl	L-arabitol metabolism													biological_process											owl:Class	
GO:0060835	biolink:NamedThing	transforming growth factor receptor beta signaling pathway involved in oral/aboral axis specification	A series of molecular signals initiated by the binding of an extracellular ligand to a transforming growth factor beta receptor on the surface of a target cell, which contributes to the specification of the oral/aboral axis.	tmpzr1t_l9r_go_relaxed.owl	transforming growth factor receptor beta signalling pathway involved in oral/aboral axis specification							dph	2009-08-11T03:30:40Z					biological_process											owl:Class	
GO:2000080	biolink:NamedThing	negative regulation of canonical Wnt signaling pathway involved in controlling type B pancreatic cell proliferation	Any process that stops, prevents, or reduces the frequency, rate or extent of canonical Wnt signaling pathway modulating the rate or frequency of pancreatic B cell proliferation.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of canonical Wnt receptor signaling pathway involved in pancreatic beta cell proliferation|negative regulation of canonical Wnt-activated signaling pathway involved in controlling type B pancreatic cell proliferation|negative regulation of canonical Wnt receptor signaling pathway involved in controlling pancreatic B cell proliferation|negative regulation of canonical Wnt receptor signalling pathway involved in controlling type B pancreatic cell proliferation|negative regulation of canonical Wnt receptor signalling pathway involved in controlling pancreatic B cell proliferation|negative regulation of canonical Wnt receptor signaling pathway involved in controlling type B pancreatic cell proliferation							tb	2010-08-27T11:22:58Z					biological_process											owl:Class	
GO:0006490	biolink:NamedThing	oligosaccharide-lipid intermediate biosynthetic process	The chemical reactions and pathways resulting in the formation of an oligosaccharide-lipid intermediate, such as a molecule of dolichol-P-man or dolicol-P-Glc used in N-linked glycosylation.	tmpzr1t_l9r_go_relaxed.owl	oligosaccharide-lipid intermediate assembly													biological_process											owl:Class	
GO:0062166	biolink:NamedThing	negative regulation of pseudohyphal septin ring assembly	Any process that decreases the rate, frequency or extent of pseudohyphal septin ring assembly.	tmpzr1t_l9r_go_relaxed.owl								dph	2019-11-07T15:57:39Z					biological_process											owl:Class	
GO:0106167	biolink:NamedThing	extracellular ATP signaling	A series of molecular signals mediated by the detection of extracellular ATP.	tmpzr1t_l9r_go_relaxed.owl								hjd	2019-02-06T19:21:44Z					biological_process											owl:Class	
GO:0002770	biolink:NamedThing	T cell inhibitory signaling pathway	A series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of a T cell capable of inhibiting an immune effector process contributing to an immune response.	tmpzr1t_l9r_go_relaxed.owl	T cell inhibitory signalling pathway|T-cell inhibitory signaling pathway|T lymphocyte inhibitory signaling pathway|T-lymphocyte inhibitory signaling pathway													biological_process											owl:Class	
GO:0005796	biolink:NamedThing	Golgi lumen	The volume enclosed by the membranes of any cisterna or subcompartment of the Golgi apparatus, including the cis- and trans-Golgi networks.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0061176	biolink:NamedThing	type Ib terminal bouton	Terminal inflated portion of the axon of a glutamatergic neuron, containing the specialized apparatus necessary for the tonic release neurotransmitters that will induce the contraction of muscle. Type Ib terminal boutons are larger than type Is terminal boutons.	tmpzr1t_l9r_go_relaxed.owl	type Ib terminal button							dph	2010-07-13T09:20:04Z					cellular_component											owl:Class	
GO:0061174	biolink:NamedThing	type I terminal bouton	Terminal inflated portion of the axon of a glutamatergic neuron, containing the specialized apparatus necessary to release neurotransmitters that will induce the contraction of muscle. The axon terminus is considered to be the whole region of thickening and the terminal bouton is a specialized region of it.	tmpzr1t_l9r_go_relaxed.owl	type I terminal button							dph	2010-07-13T09:13:05Z					cellular_component											owl:Class	
GO:0102983	biolink:NamedThing	xylogalacturonan beta-1,3-xylosyltransferase activity	Catalysis of the reaction: UDP-alpha-D-xylose + a homogalacturonan <=> UDP + 4 H+ + a xylogalacturonan.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-9589|EC:2.4.2.41									molecular_function											owl:Class	
GO:1902332	biolink:NamedThing	bacterial-type DNA replication DNA duplex unwinding	Any DNA duplex unwinding that is involved in bacterial-type DNA replication.	tmpzr1t_l9r_go_relaxed.owl	DNA unwinding involved in bacterial-type DNA replication|duplex DNA melting involved in bacterial-type DNA replication|DNA duplex unwinding involved in bacterial-type DNA replication							jl	2013-07-25T10:48:34Z					biological_process											owl:Class	
GO:0060275	biolink:NamedThing	maintenance of stationary phase in response to starvation	The homeostatic process in which a population of cells changes its metabolic activity resulting in the rate of death in the population equaling the rate of reproduction in response to limited nutrients in the environment.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0060274	biolink:NamedThing	maintenance of stationary phase	The homeostatic process in which a population of cells changes its metabolic activity resulting in the rate of death in the population equaling the rate of reproduction. Stationary phase can be in response to limited nutrients or a build-up of toxic substances in the environment.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1901730	biolink:NamedThing	monensin A biosynthetic process	The chemical reactions and pathways resulting in the formation of monensin A.	tmpzr1t_l9r_go_relaxed.owl	monensin A synthesis|monensin A anabolism|monensin formation|monensin synthesis|monensin A biosynthesis|monensin anabolism|monensin A formation|monensin biosynthesis							yaf	2013-01-09T11:55:53Z					biological_process											owl:Class	
GO:1901728	biolink:NamedThing	monensin A metabolic process	The chemical reactions and pathways involving monensin A.	tmpzr1t_l9r_go_relaxed.owl	monensin metabolism|monensin A metabolism							yaf	2013-01-09T11:55:45Z					biological_process											owl:Class	
GO:0034377	biolink:NamedThing	plasma lipoprotein particle assembly	The non-covalent aggregation and arrangement of proteins and lipids to form a plasma lipoprotein particle.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0065005	biolink:NamedThing	protein-lipid complex assembly	The aggregation, arrangement and bonding together of proteins and lipids to form a protein-lipid complex.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0033760	biolink:NamedThing	2'-deoxymugineic-acid 2'-dioxygenase activity	Catalysis of the reaction: 2'-deoxymugineate + 2-oxoglutarate + O(2) = CO(2) + H(+) + mugineate + succinate.	tmpzr1t_l9r_go_relaxed.owl	IDS3|2'-deoxymugineic acid,2-oxoglutarate:oxygen oxidoreductase (2-hydroxylating) activity				RHEA:12200|KEGG_REACTION:R07185|MetaCyc:1.14.11.24-RXN|EC:1.14.11.24									molecular_function											owl:Class	
GO:0007136	biolink:NamedThing	meiotic prophase II	The cell cycle phase which is the first stage of meiosis II and during which chromosomes condense and the two daughter centrioles and their asters migrate toward the poles of the cell.	tmpzr1t_l9r_go_relaxed.owl						Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).								biological_process											owl:Class	
GO:0072655	biolink:NamedThing	establishment of protein localization to mitochondrion	The directed movement of a protein to the mitochondrion or a part of the mitochondrion.	tmpzr1t_l9r_go_relaxed.owl	establishment of protein localization in mitochondrion|establishment of protein localisation to mitochondrion							mah	2011-02-14T02:28:54Z					biological_process											owl:Class	
GO:0003884	biolink:NamedThing	D-amino-acid oxidase activity	Catalysis of the reaction: a D-amino acid + H2O + O2 = a 2-oxo acid + NH3 + hydrogen peroxide.	tmpzr1t_l9r_go_relaxed.owl	L-amino acid:O2 oxidoreductase activity|D-amino-acid:oxygen oxidoreductase (deaminating)|new yellow enzyme				EC:1.4.3.3|MetaCyc:D-AMINO-ACID-OXIDASE-RXN|Reactome:R-HSA-389821|RHEA:21816									molecular_function											owl:Class	
GO:0008762	biolink:NamedThing	UDP-N-acetylmuramate dehydrogenase activity	Catalysis of the reaction: UDP-N-acetylmuramate + NADP+ = UDP-N-acetyl-3-O-(1-carboxyvinyl)-D-glucosamine + NADPH + H+.	tmpzr1t_l9r_go_relaxed.owl	uridine-5'-diphospho-N-acetyl-2-amino-2-deoxy-3-O-lactylglucose:NADP-oxidoreductase activity|uridine diphosphoacetylpyruvoylglucosamine reductase activity|UDP-GlcNAc-enoylpyruvate reductase activity|uridine diphospho-N-acetylglucosamine-enolpyruvate reductase activity|UDP-N-acetylmuramate:NADP+ oxidoreductase activity|UDP-N-acetylglucosamine-enoylpyruvate reductase activity|UDP-N-acetylenolpyruvoylglucosamine reductase activity|MurB reductase				RHEA:12248|MetaCyc:UDPNACETYLMURAMATEDEHYDROG-RXN|EC:1.3.1.98									molecular_function											owl:Class	
GO:0006475	biolink:NamedThing	internal protein amino acid acetylation	The addition of an acetyl group to a non-terminal amino acid in a protein.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0047656	biolink:NamedThing	alpha,alpha-trehalose phosphorylase activity	Catalysis of the reaction: alpha,alpha-trehalose + phosphate = D-glucose + beta-D-glucose 1-phosphate.	tmpzr1t_l9r_go_relaxed.owl	trehalose phosphorylase|alpha,alpha-trehalose:phosphate beta-D-glucosyltransferase activity|a,a-trehalose phosphorylase activity				EC:2.4.1.64|RHEA:23512|MetaCyc:ALPHAALPHA-TREHALOSE-PHOSPHORYLASE-RXN									molecular_function											owl:Class	
GO:0070944	biolink:NamedThing	neutrophil-mediated killing of bacterium	The directed killing of a bacterium by a neutrophil.	tmpzr1t_l9r_go_relaxed.owl	neutrophil mediated killing of bacterium							mah	2009-10-01T01:55:56Z					biological_process											owl:Class	
GO:0051020	biolink:NamedThing	GTPase binding	Binding to a GTPase, any enzyme that catalyzes the hydrolysis of GTP.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0140282	biolink:NamedThing	carbon-nitrogen ligase activity on lipid II	Catalysis of the reaction: L-glutamine + lipid II + ATP + H2O = L-glutamate + beta-D-GlcNAc(1->4)-Mur2Ac(oyl-L-Ala-D-isoGln-L-Lys-D-Ala-D-Ala)-diphospho-di-trans,octa-cis-undecaprenol + ADP + phosphate.	tmpzr1t_l9r_go_relaxed.owl	undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl pentapeptide amidotransferase (glutamine-hydrolyzing) activity|L-glutamate--lipid II transaminase activity	https://github.com/geneontology/go-ontology/issues/16422			RHEA:57928|EC:6.3.5.13			pg	2018-10-08T19:12:57Z					molecular_function											owl:Class	
GO:0016884	biolink:NamedThing	carbon-nitrogen ligase activity, with glutamine as amido-N-donor	Catalysis of the transfer of the amide nitrogen of glutamine to a substrate. Usually composed of two subunits or domains, one that first hydrolyzes glutamine, and then transfers the resulting ammonia to the second subunit (or domain), where it acts as a source of nitrogen.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/16422			EC:6.3.5.-							GO:0016003		molecular_function											owl:Class	
GO:0060731	biolink:NamedThing	positive regulation of intestinal epithelial structure maintenance	Any process the increases the rate, frequency or extent of intestinal epithelial structure maintenance, a tissue homeostatic process required for the maintenance of the structure of the intestinal epithelium.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-06-12T01:51:50Z					biological_process											owl:Class	
GO:0004306	biolink:NamedThing	ethanolamine-phosphate cytidylyltransferase activity	Catalysis of the reaction: CTP + ethanolamine phosphate = diphosphate + CDP-ethanolamine.	tmpzr1t_l9r_go_relaxed.owl	ethanolamine phosphate cytidylyltransferase activity|CTP-phosphoethanolamine cytidylyltransferase activity|ET|CTP:ethanolamine-phosphate cytidylyltransferase activity|phosphoethanolamine cytidylyltransferase activity|CTP:phosphoethanolamine cytidylyltransferase activity|phosphorylethanolamine transferase activity				RHEA:24592|EC:2.7.7.14|MetaCyc:2.7.7.14-RXN|Reactome:R-HSA-1483190									molecular_function											owl:Class	
GO:2000801	biolink:NamedThing	negative regulation of endocardial cushion to mesenchymal transition involved in heart valve formation	Any process that stops, prevents or reduces the frequency, rate or extent of endocardial cushion to mesenchymal transition involved in heart valve formation.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of endocardial cushion to mesenchymal transition involved in valve formation							bf	2011-07-01T12:31:22Z					biological_process											owl:Class	
GO:0140050	biolink:NamedThing	negative regulation of endocardial cushion to mesenchymal transition	Any process that stops, prevents or reduces the frequency, rate or extent of endocardial cushion to mesenchymal transition.	tmpzr1t_l9r_go_relaxed.owl								pg	2017-06-26T09:02:27Z					biological_process											owl:Class	
GO:0005506	biolink:NamedThing	iron ion binding	Binding to an iron (Fe) ion.	tmpzr1t_l9r_go_relaxed.owl	iron binding													molecular_function											owl:Class	
GO:0046914	biolink:NamedThing	transition metal ion binding	Binding to a transition metal ions; a transition metal is an element whose atom has an incomplete d-subshell of extranuclear electrons, or which gives rise to a cation or cations with an incomplete d-subshell. Transition metals often have more than one valency state. Biologically relevant transition metals include vanadium, manganese, iron, copper, cobalt, nickel, molybdenum and silver.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0009033	biolink:NamedThing	trimethylamine-N-oxide reductase activity	Catalysis of the reaction: NADH + H+ + trimethylamine-N-oxide = NAD+ + trimethylamine + H2O.	tmpzr1t_l9r_go_relaxed.owl	trimethylamine oxide reductase|trimethylamine N-oxide reductase|trimethylamine oxidase activity|NADH:trimethylamine-N-oxide oxidoreductase				MetaCyc:TMAOREDUCT-RXN|RHEA:22024									molecular_function											owl:Class	
GO:0032525	biolink:NamedThing	somite rostral/caudal axis specification	The establishment, maintenance and elaboration of the rostro-caudal axis of a somite, prior to the morphological formation of a somite boundary.	tmpzr1t_l9r_go_relaxed.owl	somite rostrocaudal polarity|somite rostrocaudal axis specification													biological_process											owl:Class	
GO:0009948	biolink:NamedThing	anterior/posterior axis specification	The establishment, maintenance and elaboration of the anterior/posterior axis. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism.	tmpzr1t_l9r_go_relaxed.owl	anterior/posterior axis determination													biological_process											owl:Class	
GO:1905379	biolink:NamedThing	beta-N-acetylhexosaminidase complex	A protein complex which is capable of beta-N-acetylhexosaminidase activity.	tmpzr1t_l9r_go_relaxed.owl	HEX S complex|HEX B complex|HEX A complex					An example of this is HEXB in human (UniProt symbol P07686) in PMID:6458607 (inferred from direct assay).		bhm	2016-08-18T08:26:15Z					cellular_component											owl:Class	
GO:0036193	biolink:NamedThing	2-hydroxy-1,4-benzoxazin-3-one monooxygenase activity	Catalysis of the reaction: 2-hydroxy-2H-1,4-benzoxazin-3(4H)-one + NAD(P)H + H+ + O2 = 2,4-dihydroxy-2H-1,4-benzoxazin-3(4H)-one + NAD(P)+ + H2O.	tmpzr1t_l9r_go_relaxed.owl					EC:1.14.14.110|RHEA:31939|KEGG_REACTION:R07423			bf	2012-04-19T11:54:34Z					molecular_function											owl:Class	
GO:0120210	biolink:NamedThing	rod telodendria	Rod telodendria are projections that originate from the rod pedicle and form gap junctions with other photoreceptors within the outer plexiform layer of the retina.	tmpzr1t_l9r_go_relaxed.owl								krc	2019-05-21T00:34:22Z					cellular_component											owl:Class	
GO:0120208	biolink:NamedThing	telodendria	Telodendria are projections that originate from the axon pedicle and form gap junctions with other neurons.	tmpzr1t_l9r_go_relaxed.owl								krc	2019-05-20T23:50:28Z					cellular_component											owl:Class	
GO:0004140	biolink:NamedThing	dephospho-CoA kinase activity	Catalysis of the reaction: 3'-dephospho-CoA + ATP = ADP + CoA + 2 H(+).	tmpzr1t_l9r_go_relaxed.owl	ATP:dephospho-CoA 3'-phosphotransferase activity|dephosphocoenzyme A kinase activity|dephosphocoenzyme A kinase (phosphorylating)|3'-dephospho-CoA kinase activity				EC:2.7.1.24|RHEA:18245|MetaCyc:DEPHOSPHOCOAKIN-RXN|KEGG_REACTION:R00130|Reactome:R-HSA-196773									molecular_function											owl:Class	
GO:0004021	biolink:NamedThing	L-alanine:2-oxoglutarate aminotransferase activity	Catalysis of the reaction: 2-oxoglutarate + L-alanine = L-glutamate + pyruvate.	tmpzr1t_l9r_go_relaxed.owl	alanine aminotransferase activity|pyruvate-alanine aminotransferase activity|pyruvate-glutamate transaminase activity|glutamic-pyruvic aminotransferase activity|alanine-pyruvate aminotransferase activity|alanine transaminase activity|beta-alanine aminotransferase|ALT|glutamic acid-pyruvic acid transaminase activity|GPT|L-alanine aminotransferase activity|L-alanine transaminase activity|L-alanine-alpha-ketoglutarate aminotransferase activity|glutamic--alanine transaminase activity|alanine-alpha-ketoglutarate aminotransferase activity|pyruvate transaminase activity|glutamic--pyruvic transaminase activity				Reactome:R-HSA-70524|EC:2.6.1.2|RHEA:19453|MetaCyc:ALANINE-AMINOTRANSFERASE-RXN|Reactome:R-HSA-507775|Reactome:R-HSA-70523|KEGG_REACTION:R00258|Reactome:R-HSA-507749									molecular_function											owl:Class	
GO:0047635	biolink:NamedThing	alanine-oxo-acid transaminase activity	Catalysis of the reaction: L-alanine + a 2-oxo acid = pyruvate + an L-amino acid.	tmpzr1t_l9r_go_relaxed.owl	leucine-alanine transaminase activity|alanine-oxo-acid aminotransferase activity|alanine--oxo-acid aminotransferase activity|L-alanine:2-oxo-acid aminotransferase activity|L-alanine-alpha-keto acid aminotransferase activity|alanine-oxo acid aminotransferase activity|alanine-keto acid aminotransferase activity				RHEA:19953|EC:2.6.1.12|MetaCyc:ALANINE--OXO-ACID-AMINOTRANSFERASE-RXN									molecular_function											owl:Class	
GO:0036476	biolink:NamedThing	neuron death in response to hydrogen peroxide	Any biological process that results in permanent cessation of all vital functions of a neuron upon exposure to hydrogen peroxide (H2O2).	tmpzr1t_l9r_go_relaxed.owl	neuronal cell death in response to hydrogen peroxide|hydrogen peroxide-induced neuron death|neuron death in response to H2O2					This term should not be used for direct annotation. The only exception should be when experimental data (e.g., staining with trypan blue or propidium iodide or use of neuron-specific markers) show that neuron death has occurred, but fail to provide details on death modality (accidental versus programmed). When information is provided on the neuron death mechanism, annotations should be made to the appropriate descendant of 'cell death' (such as, but not limited to, GO:0097300 'programmed necrotic cell death', GO:0006915 'apoptotic process' or GO:0010421 'hydrogen peroxide-mediated programmed cell death'), and the cell type captured as an annotation extension; or the term GO:0051402 'neuron apoptotic process' may be considered, if appropriate.		bf	2014-07-21T11:46:31Z					biological_process											owl:Class	
GO:0036474	biolink:NamedThing	cell death in response to hydrogen peroxide	Any biological process that results in permanent cessation of all vital functions of a cell upon exposure to hydrogen peroxide (H2O2).	tmpzr1t_l9r_go_relaxed.owl	hydrogen peroxide-mediated cell death|cell death in response to H2O2					This term should not be used for direct annotation. The only exception should be when experimental data (e.g., staining with trypan blue or propidium iodide) show that cell death has occurred, but fail to provide details on death modality (accidental versus programmed). When information is provided on the cell death mechanism, annotations should be made to the appropriate descendant of 'cell death' (such as, but not limited to, GO:0010421 'hydrogen peroxide-mediated programmed cell death'). Also, if experimental data suggest that a gene product influences cell death indirectly, rather than being involved in the death process directly, consider annotating to a 'regulation' term.		bf	2014-07-21T11:42:28Z					biological_process											owl:Class	
GO:1901533	biolink:NamedThing	negative regulation of hematopoietic progenitor cell differentiation	Any process that stops, prevents or reduces the frequency, rate or extent of hematopoietic progenitor cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of hemopoietic progenitor cell differentiation|inhibition of hemopoietic progenitor cell differentiation|inhibition of hematopoietic progenitor cell differentiation|negative regulation of haemopoietic progenitor cell differentiation|down regulation of hematopoietic progenitor cell differentiation|down-regulation of haemopoietic progenitor cell differentiation|downregulation of haemopoietic progenitor cell differentiation|inhibition of haematopoietic progenitor cell differentiation|down regulation of hemopoietic progenitor cell differentiation|down-regulation of hematopoietic progenitor cell differentiation|downregulation of haematopoietic progenitor cell differentiation|negative regulation of haematopoietic progenitor cell differentiation|inhibition of haemopoietic progenitor cell differentiation|down regulation of haemopoietic progenitor cell differentiation|down-regulation of hemopoietic progenitor cell differentiation|downregulation of hematopoietic progenitor cell differentiation|down regulation of haematopoietic progenitor cell differentiation|downregulation of hemopoietic progenitor cell differentiation|down-regulation of haematopoietic progenitor cell differentiation							vk	2012-10-24T11:23:06Z					biological_process											owl:Class	
GO:0015224	biolink:NamedThing	biopterin transmembrane transporter activity	Enables the transfer of biopterin from one side of a membrane to the other. Biopterin is a growth factor for certain protozoans and some insects; it is widely distributed in tissues and functions in a reduced form, tetrahydrobiopterin, as a hydroxylation coenzyme.	tmpzr1t_l9r_go_relaxed.owl	biopterin transporter activity													molecular_function											owl:Class	
GO:0046457	biolink:NamedThing	prostanoid biosynthetic process	The chemical reactions and pathways resulting in the formation of prostanoids, any compound based on or derived from the prostanoate structure.	tmpzr1t_l9r_go_relaxed.owl	prostanoid anabolism|prostanoid synthesis|prostanoid biosynthesis|prostanoid formation				Wikipedia:Prostanoid#Biosynthesis									biological_process											owl:Class	
GO:0009903	biolink:NamedThing	chloroplast avoidance movement	The relocation process in which chloroplasts in photosynthetic cells avoid strong light and move away from it in order to preserve the photosynthetic machinery.	tmpzr1t_l9r_go_relaxed.owl	high-fluence-rate response													biological_process											owl:Class	
GO:0098874	biolink:NamedThing	spike train	A series of sequential, propagated action potentials occurring in a single cell.	tmpzr1t_l9r_go_relaxed.owl	spike-train|burst of action potentials											GO:0099603		biological_process											owl:Class	
GO:0070106	biolink:NamedThing	interleukin-27-mediated signaling pathway	A series of molecular signals initiated by the binding of interleukin-27 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.	tmpzr1t_l9r_go_relaxed.owl	interleukin-27-mediated signalling pathway|IL27RA/IL6ST signaling pathway|IL-27-mediated signaling pathway													biological_process											owl:Class	
GO:1902380	biolink:NamedThing	positive regulation of endoribonuclease activity	Any process that activates or increases the frequency, rate or extent of endoribonuclease activity.	tmpzr1t_l9r_go_relaxed.owl	upregulation of endoribonuclease activity|up-regulation of endonuclease G activity|positive regulation of endonuclease G activity|activation of endonuclease G activity|up regulation of endonuclease G activity|upregulation of endonuclease G activity|up-regulation of endoribonuclease activity|up regulation of endoribonuclease activity|activation of endoribonuclease activity							bf	2013-09-02T14:14:29Z					biological_process											owl:Class	
GO:2000839	biolink:NamedThing	positive regulation of androstenedione secretion	Any process that activates or increases the frequency, rate or extent of androstenedione secretion.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of androst-4-ene-3,17-dione secretion							bf	2011-07-26T08:40:42Z					biological_process											owl:Class	
GO:1905576	biolink:NamedThing	ganglioside GT1b binding	Binding to ganglioside GT1b.	tmpzr1t_l9r_go_relaxed.owl								pga	2016-10-19T11:17:17Z					molecular_function											owl:Class	
GO:0005129	biolink:NamedThing	granulocyte macrophage colony-stimulating factor receptor binding	Binding to a granulocyte macrophage colony-stimulating factor receptor.	tmpzr1t_l9r_go_relaxed.owl	GM-CSF receptor binding|granulocyte macrophage colony stimulating factor receptor binding|granulocyte macrophage colony-stimulating factor receptor ligand|granulocyte macrophage colony-stimulating factor|GM-CSF receptor ligand|GMC-SF receptor ligand													molecular_function											owl:Class	
GO:0015366	biolink:NamedThing	malate:proton symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: malate(out) + H+(out) = malate(in) + H+(in).	tmpzr1t_l9r_go_relaxed.owl	malate:hydrogen symporter activity|L-malic acid:proton symporter activity|malate permease|L-malic acid permease													molecular_function											owl:Class	
GO:0016144	biolink:NamedThing	S-glycoside biosynthetic process	The chemical reactions and pathways resulting in the formation of S-glycosides, any compound in which a glycosyl group has been substituted into a thiol group.	tmpzr1t_l9r_go_relaxed.owl	S-glycoside formation|thioglycoside biosynthetic process|S-glycoside biosynthesis|S-glycoside synthesis|S-glycoside anabolism|thioglycoside biosynthesis													biological_process											owl:Class	
GO:0032204	biolink:NamedThing	regulation of telomere maintenance	Any process that modulates the frequency, rate or extent of a process that affects and monitors the activity of telomeric proteins and the length of telomeric DNA.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0016993	biolink:NamedThing	precorrin-8X methylmutase activity	Catalysis of the reaction: precorrin-8X = hydrogenobyrinate.	tmpzr1t_l9r_go_relaxed.owl	precorrin isomerase activity|HBA synthase activity|precorrin-8X 11,12-methylmutase activity|hydrogenobyrinic acid-binding protein activity				MetaCyc:5.4.1.2-RXN|RHEA:22512|EC:5.4.99.61									molecular_function											owl:Class	
GO:0030164	biolink:NamedThing	protein denaturation	Structural change in proteins which destroys the native, active configuration without rupture of peptide bonds.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Denaturation#Protein_denaturation									biological_process											owl:Class	
GO:0048797	biolink:NamedThing	swim bladder formation	The process that gives rise to the swim bladder. This process pertains to the initial formation of a structure from unspecified parts. The swim bladder is used by some fishes to maintain buoyancy and may function in addition as a sound producing organ, a sound receptor, and a respiratory organ.	tmpzr1t_l9r_go_relaxed.owl	gas bladder formation|gas bladder biosynthesis													biological_process											owl:Class	
GO:0047898	biolink:NamedThing	formate dehydrogenase (cytochrome) activity	Catalysis of the reaction: formate + ferricytochrome b1 = CO2 + ferrocytochrome b1.	tmpzr1t_l9r_go_relaxed.owl	formate:ferricytochrome-b1 oxidoreductase activity|formate:cytochrome b1 oxidoreductase activity				EC:1.2.2.1|RHEA:21520|MetaCyc:FORMATE-DEHYDROGENASE-CYTOCHROME-RXN									molecular_function											owl:Class	
GO:0016622	biolink:NamedThing	oxidoreductase activity, acting on the aldehyde or oxo group of donors, cytochrome as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which an aldehyde or ketone (oxo) group acts as a hydrogen or electron donor and reduces a cytochrome.	tmpzr1t_l9r_go_relaxed.owl					EC:1.2.2.-									molecular_function											owl:Class	
GO:1901395	biolink:NamedThing	regulation of transforming growth factor beta2 activation	Any process that modulates the frequency, rate or extent of transforming growth factor beta2 activation.	tmpzr1t_l9r_go_relaxed.owl	regulation of TGF-beta 2 activation|regulation of TGFbeta 2 activation|regulation of TGFB2 activation							bf	2012-10-01T10:46:50Z					biological_process											owl:Class	
GO:0030786	biolink:NamedThing	(RS)-norcoclaurine 6-O-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + (RS)-norcoclaurine = S-adenosyl-L-homocysteine + (RS)-coclaurine.	tmpzr1t_l9r_go_relaxed.owl	S-adenosyl-L-methionine:(RS)-norcoclaurine 6-O-methyltransferase activity				RHEA:19941|MetaCyc:2.1.1.128-RXN|EC:2.1.1.128									molecular_function											owl:Class	
GO:0005524	biolink:NamedThing	ATP binding	Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-265682									molecular_function											owl:Class	
GO:1903121	biolink:NamedThing	regulation of TRAIL-activated apoptotic signaling pathway	Any process that modulates the frequency, rate or extent of TRAIL-activated apoptotic signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	regulation of tumor necrosis factor-related apoptosis-inducing ligand apoptotic signaling pathway|regulation of TRAIL-induced apoptotic signaling pathway|regulation of TRAIL-activated extrinsic apoptotic signaling pathway							bf	2014-06-17T12:39:15Z					biological_process											owl:Class	
GO:0005684	biolink:NamedThing	U2-type spliceosomal complex	Any spliceosomal complex that forms during the splicing of a messenger RNA primary transcript to excise an intron that has canonical consensus sequences near the 5' and 3' ends.	tmpzr1t_l9r_go_relaxed.owl	major (U2-type) spliceosomal complex|GT-AG spliceosome|major spliceosomal complex					A U2-type complex refers to any of the snRNP-based complexes that form during splicing that uses U2 (as opposed to U12). There are complexes that form during U2-splicing that don't necessarily contain the U2 snRNP.								cellular_component											owl:Class	
GO:0045114	biolink:NamedThing	beta 2 integrin biosynthetic process	The chemical reactions and pathways resulting in the formation of beta 2 integrins, a subfamily of integrins which contain the beta 2 subunit.	tmpzr1t_l9r_go_relaxed.owl	beta 2 integrin anabolism|beta 2 integrin synthesis|beta 2 integrin biosynthesis|beta 2 integrin formation													biological_process											owl:Class	
GO:0042070	biolink:NamedThing	maintenance of oocyte nucleus location involved in oocyte dorsal/ventral axis specification	Maintenance of the oocyte nucleus in a particular position within the cell during the establishment and maintenance of the axes of the oocyte. An example of this process is found In Drosophila melanogaster.	tmpzr1t_l9r_go_relaxed.owl	oocyte axis determination, oocyte nucleus anchoring|maintenance of oocyte nucleus location involved in oocyte dorsoventral axis specification|oocyte axis determination, maintenance of oocyte nucleus localization|maintenance of oocyte nucleus localization during oocyte axis determination|maintenance of oocyte nucleus location involved in oocyte dorsal-ventral axis specification|oocyte nucleus anchoring during oocyte axis determination|maintenance of oocyte nucleus location involved in oocyte dorsal/ventral axis determination|oocyte axis determination, maintenance of oocyte nucleus position|maintenance of oocyte nucleus position during oocyte axis determination											GO:0048127		biological_process											owl:Class	
GO:0002076	biolink:NamedThing	osteoblast development	The process whose specific outcome is the progression of an osteoblast over time, from its formation to the mature structure. Osteoblast development does not include the steps involved in committing a cranial neural crest cell or an osteoprogenitor cell to an osteoblast fate. An osteoblast is a cell that gives rise to bone.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0140193	biolink:NamedThing	regulation of adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in heart process	Any process that modulates the frequency, rate or extent of an adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in some heart process.	tmpzr1t_l9r_go_relaxed.owl								pg	2018-02-15T19:08:49Z					biological_process											owl:Class	
GO:0016760	biolink:NamedThing	cellulose synthase (UDP-forming) activity	Catalysis of the reaction: UDP-glucose + ((1,4)-beta-D-glucosyl)(n) = UDP + ((1,4)-beta-D-glucosyl)(n+1).	tmpzr1t_l9r_go_relaxed.owl	UDP-glucose:1,4-beta-D-glucan 4-beta-D-glucosyltransferase activity|uridine diphosphoglucose-cellulose glucosyltransferase activity|beta-glucan synthase activity|1,4-beta-glucan synthase activity|UDP-glucose-cellulose glucosyltransferase activity|UDPglucose:1,4-beta-D-glucan 4-beta-D-glucosyltransferase activity|beta-1,4-glucan synthetase activity|beta-1,4-glucan synthase activity|GS-I|UDPglucose-cellulose glucosyltransferase activity|glucan synthase activity|UDPglucose-beta-glucan glucosyltransferase activity|uridine diphosphoglucose-1,4-beta-glucan glucosyltransferase activity|beta-1,4-glucosyltransferase activity|1,4-beta-D-glucan synthase activity|UDP-glucose-1,4-beta-glucan glucosyltransferase activity|UDP-glucose-beta-D-glucan glucosyltransferase activity				MetaCyc:CELLULOSE-SYNTHASE-UDP-FORMING-RXN|EC:2.4.1.12|RHEA:19929									molecular_function											owl:Class	
GO:0030419	biolink:NamedThing	nicotianamine catabolic process	The chemical reactions and pathways resulting in the breakdown of nicotianamine, 2(S),3'2(S),3''(S)-N-(N-(3-amino-3-carboxypropyl)-3-amino-3-carboxypropyl)-azetidine-2-carboxylic acid.	tmpzr1t_l9r_go_relaxed.owl	nicotianamine catabolism|nicotianamine degradation|nicotianamine breakdown													biological_process											owl:Class	
GO:0030417	biolink:NamedThing	nicotianamine metabolic process	The chemical reactions and pathways involving nicotianamine, 2(S),3'2(S),3''(S)-N-(N-(3-amino-3-carboxypropyl)-3-amino-3-carboxypropyl)-azetidine-2-carboxylic acid.	tmpzr1t_l9r_go_relaxed.owl	nicotianamine metabolism													biological_process											owl:Class	
GO:0018892	biolink:NamedThing	cyclohexylsulfamate metabolic process	The chemical reactions and pathways involving cyclohexylsulfamate, also known as cyclamic acid. Sodium cyclohexylsulfamate (CHS-Na) was a widely used sweetening agent but was banned because of the suspicion of carcinogenicity and metabolic conversion to cyclohexylamine (CHA), a toxic substance. It is now used as a fungicide.	tmpzr1t_l9r_go_relaxed.owl	cyclohexylsulfamate metabolism|cyclohexylsulphamate metabolism|cyclohexylsulphamate metabolic process				UM-BBD_pathwayID:chs									biological_process											owl:Class	
GO:1904118	biolink:NamedThing	regulation of otic vesicle morphogenesis	Any process that modulates the frequency, rate or extent of otic vesicle morphogenesis.	tmpzr1t_l9r_go_relaxed.owl								pga	2015-04-07T14:00:56Z					biological_process											owl:Class	
GO:0014850	biolink:NamedThing	response to muscle activity	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a muscle activity stimulus.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0014823	biolink:NamedThing	response to activity	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an activity stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to exercise													biological_process											owl:Class	
GO:0048775	biolink:NamedThing	regulation of leucophore differentiation	Any process that modulates the frequency, rate or extent of leucophore differentiation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0017185	biolink:NamedThing	peptidyl-lysine hydroxylation	The hydroxylation of peptidyl-lysine to form peptidyl-hydroxylysine.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0080084	biolink:NamedThing	5S rDNA binding	Binding to a 5S rDNA sequence, encoding ribosomal 5S rRNA, which is individually transcribed by RNA polymerase III, rather than by RNA polymerase I, in species where it exists.	tmpzr1t_l9r_go_relaxed.owl								dhl	2009-04-22T02:32:20Z					molecular_function											owl:Class	
GO:0000182	biolink:NamedThing	rDNA binding	Binding to a DNA sequence encoding a ribosomal RNA.	tmpzr1t_l9r_go_relaxed.owl	ribosomal DNA binding													molecular_function											owl:Class	
GO:0061900	biolink:NamedThing	glial cell activation	A change in morphology and behavior of a glial cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor.	tmpzr1t_l9r_go_relaxed.owl								dph	2017-06-13T13:06:23Z					biological_process											owl:Class	
GO:0000707	biolink:NamedThing	meiotic DNA recombinase assembly	During meiosis, the aggregation, arrangement and bonding together of strand exchange proteins (recombinases) to form higher order oligomers on single-stranded DNA.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0000730	biolink:NamedThing	DNA recombinase assembly	The aggregation, arrangement and bonding together of strand exchange proteins (recombinases) into higher order oligomers on single-stranded DNA.	tmpzr1t_l9r_go_relaxed.owl	Rad51 nucleoprotein filament formation													biological_process											owl:Class	
GO:2001188	biolink:NamedThing	regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell	Any process that modulates the frequency, rate or extent of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell.	tmpzr1t_l9r_go_relaxed.owl	regulation of T lymphocyte activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell|regulation of T-cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell|regulation of T-lymphocyte activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell							yaf	2011-11-03T01:31:30Z					biological_process											owl:Class	
GO:0060793	biolink:NamedThing	sweat gland placode formation	The developmental process in which the sweat gland placode forms. An sweat gland placode is a thickening of the ectoderm that will give rise to the sweat gland bud.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-08-04T12:38:10Z					biological_process											owl:Class	
GO:0002388	biolink:NamedThing	immune response in Peyer's patch	Immune response taking place in the Peyer's patch, nodular lymphoid structures on the serosal surface of the small intestine.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0002387	biolink:NamedThing	immune response in gut-associated lymphoid tissue	Immune response taking place in the gut-associated lymphoid tissue (GALT). GALT includes Peyer's patches, appendix, and solitary lymph nodules.	tmpzr1t_l9r_go_relaxed.owl	immune response in GALT													biological_process											owl:Class	
GO:0003219	biolink:NamedThing	cardiac right ventricle formation	The developmental process pertaining to the initial formation of a right cardiac ventricle from unspecified parts.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-10-13T09:55:38Z					biological_process											owl:Class	
GO:0080073	biolink:NamedThing	spermidine:coumaroyl CoA N-acyltransferase activity	Catalysis of the transfer of a coumaroyl group to a nitrogen atom on the spermidine molecule.	tmpzr1t_l9r_go_relaxed.owl								dhl	2009-04-13T04:16:59Z					molecular_function											owl:Class	
GO:0047978	biolink:NamedThing	hexadecanol dehydrogenase activity	Catalysis of the reaction: hexadecanol + NAD+ = hexadecanal + NADH.	tmpzr1t_l9r_go_relaxed.owl	hexadecanol:NAD+ oxidoreductase activity				MetaCyc:HEXADECANOL-DEHYDROGENASE-RXN|EC:1.1.1.164|RHEA:22056									molecular_function											owl:Class	
GO:0070187	biolink:NamedThing	shelterin complex	A nuclear telomere cap complex that is formed by the association of telomeric ssDNA- and dsDNA-binding proteins with telomeric DNA, and is involved in telomere protection and recruitment of telomerase. The complex is known to contain TERF1, TERF2, POT1, RAP1, TINF2 and ACD in mammalian cells, and Pot1, Tpz1, Rap1, Rif1, Rif2 and Taz1 in Saccharomyces. Taz1 and Rap1 (or their mammalian equivalents) form a dsDNA-binding subcomplex, Pot1 and Tpz1 form an ssDNA-binding subcomplex, and the two subcomplexes are bridged by Poz1, which acts as an effector molecule along with Ccq1.	tmpzr1t_l9r_go_relaxed.owl	Pot1 complex|Pot1-Tpz1 complex|telosome													cellular_component											owl:Class	
GO:0000783	biolink:NamedThing	nuclear telomere cap complex	A complex of DNA and protein located at the end of a linear chromosome in the nucleus that protects and stabilizes a linear chromosome.	tmpzr1t_l9r_go_relaxed.owl						Note that this term can be used in place of the obsolete cellular component term 'telomere ; GO:0005696'. Use with caution because this term refers to a specific protein complex and not a region of the chromosome.								cellular_component											owl:Class	
GO:0022401	biolink:NamedThing	negative adaptation of signaling pathway	The negative regulation of a signal transduction pathway in response to a stimulus upon prolonged exposure to that stimulus.	tmpzr1t_l9r_go_relaxed.owl	negative adaptation of signalling pathway|negative adaptation of signal transduction pathway													biological_process											owl:Class	
GO:0003022	biolink:NamedThing	detection of pH by chemoreceptor signaling	The process in which information about the levels of hydrogen ions are received and are converted to a molecular signal by chemoreceptors.	tmpzr1t_l9r_go_relaxed.owl	detection of pH by chemoreceptor signalling													biological_process											owl:Class	
GO:0003030	biolink:NamedThing	detection of hydrogen ion	The series of events in which a hydrogen ion stimulus is received by a cell and converted into a molecular signal.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0030687	biolink:NamedThing	preribosome, large subunit precursor	A preribosomal complex consisting of 27SA, 27SB, and/or 7S pre-rRNA, 5S rRNA, ribosomal proteins including late-associating large subunit proteins, and associated proteins; a precursor of the eukaryotic cytoplasmic large ribosomal subunit.	tmpzr1t_l9r_go_relaxed.owl	66S preribosome					Note that this complex is 66S in Saccharomyces.								cellular_component											owl:Class	
GO:0030684	biolink:NamedThing	preribosome	Any complex of pre-rRNAs, ribosomal proteins, and associated proteins formed during ribosome biogenesis.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0010183	biolink:NamedThing	pollen tube guidance	The process in which the growth of pollen tube is directed towards the female gametophyte.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0051349	biolink:NamedThing	positive regulation of lyase activity	Any process that activates or increases the frequency, rate or extent of lyase activity, the catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of lyase activity|stimulation of lyase activity|upregulation of lyase activity|lyase activator|up regulation of lyase activity|activation of lyase activity													biological_process											owl:Class	
GO:0089720	biolink:NamedThing	caspase binding	Binding to a caspase family protein.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0031508	biolink:NamedThing	pericentric heterochromatin assembly	The assembly of chromatin located adjacent to the CENP-A rich centromere 'central core' and characterized by the modified histone H3K9me3, into heterochromatin, resulting in the repression of transcription of centromeric DNA.	tmpzr1t_l9r_go_relaxed.owl	centromeric heterochromatin biosynthesis|heterochromatic silencing at centromere|chromatin silencing at centromere|chromatin silencing at pericentric region|centromere chromatin silencing|chromatin silencing at centromere outer repeat region|centric heterochromatin formation|centromeric heterochromatin formation|centromeric silencing	https://github.com/geneontology/go-ontology/issues/19112|https://github.com/geneontology/go-ontology/issues/18954						mah	2013-07-17T15:21:38Z			GO:0030702|GO:1990141		biological_process											owl:Class	
GO:0086097	biolink:NamedThing	phospholipase C-activating angiotensin-activated signaling pathway	An angiotensin-mediated signaling pathway where the activated receptor transmits the signal via Gq-mediated activation of phospholipase C (PLC). PLC hydrolyses phosphatidylinositol 4,5-bisphosphate (PIP2) into the second messengers inositol-1,4,5,-triphosphate (IP3) and diacylglycerol (DAG). DAG activates protein kinase C (PKC), whilst IP3 binds intracellular receptors to induce the release of Ca2+ from intracellular stores.	tmpzr1t_l9r_go_relaxed.owl	phospholipase C-activating angiotensin receptor signaling pathway|Gq-coupled angiotensin receptor signaling pathway|angiotensin-mediated signaling pathway via activation of phospholipase C|phospholipase C-activating angiotensin-mediated signaling pathway|PLC-activating angiotensin receptor signaling pathway							bf	2012-06-13T11:28:15Z					biological_process											owl:Class	
GO:0140318	biolink:NamedThing	protein transporter activity	Directly binding to a specific protein and delivering it to a specific cellular location.	tmpzr1t_l9r_go_relaxed.owl	protein transport chaperone|protein carrier activity	https://github.com/geneontology/go-ontology/issues/17073			Reactome:R-HSA-9662747|Reactome:R-HSA-9662818	Examples of protein carriers include the soluble TIM chaperone complexes of S. cerevisiae Tim9-Tim10 and Tim8-Tim13, that provide a shuttle system between TOM and the membrane insertases TIM22 and SAM and, thus, ensure that precursors are kept in a translocation-competent conformation.		pg	2019-04-01T10:41:38Z					molecular_function											owl:Class	
GO:0005215	biolink:NamedThing	transporter activity	Enables the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells.	tmpzr1t_l9r_go_relaxed.owl	carrier				EC:7.-.-.-|Reactome:R-HSA-178215|Reactome:R-HSA-168313	Some transporters, such as certain members of the SLC family, are referred to as 'carriers'; however GO uses carrier with a different meaning: a carrier binds to and transports the substance (see GO:0140104 molecular carrier activity), whereas a transporter forms some pore that allows the passing of molecules.						GO:0005478		molecular_function											owl:Class	
GO:0045038	biolink:NamedThing	protein import into chloroplast thylakoid membrane	The import of proteins into the chloroplast thylakoid membranes. Proteins that are destined for the thylakoid lumen require two uptake-targeting sequences: the first targets the protein to the stroma, and the second targets the protein from the stroma to the thylakoid lumen. Four separate thylakoid-import systems deal with the proteins once they are in the stroma.	tmpzr1t_l9r_go_relaxed.owl	protein transport into chloroplast thylakoid membrane|chloroplast thylakoid membrane protein import													biological_process											owl:Class	
GO:0043686	biolink:NamedThing	co-translational protein modification	The process of covalently altering one or more amino acids in a protein after translation has begun but before the protein has been released from the ribosome.	tmpzr1t_l9r_go_relaxed.owl	co-translational amino acid modification|cotranslational protein modification|cotranslational modification|co-translational modification|cotranslational amino acid modification					This term should only be used to annotate a protein modification process that occurs after the start of translation but while the protein is still on the ribosome.								biological_process											owl:Class	
GO:1990795	biolink:NamedThing	rod bipolar cell terminal bouton	A specialized region of the axon terminus portion of a rod bipolar axon. A rod bipolar cell is a neuron found in the retina and having connections with rod photoreceptor cells and neurons in the inner plexiform layer.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-07-09T21:11:53Z					cellular_component											owl:Class	
GO:0043126	biolink:NamedThing	regulation of 1-phosphatidylinositol 4-kinase activity	Any process that modulates the activity of the enzyme 1-phosphatidylinositol 4-kinase.	tmpzr1t_l9r_go_relaxed.owl	regulation of PI4K activity													biological_process											owl:Class	
GO:0061536	biolink:NamedThing	glycine secretion	The controlled release of glycine by a cell.	tmpzr1t_l9r_go_relaxed.owl								dph	2013-06-21T16:18:23Z					biological_process											owl:Class	
GO:1900917	biolink:NamedThing	regulation of octadecene metabolic process	Any process that modulates the frequency, rate or extent of octadecene metabolic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of octadecene metabolism							tt	2012-06-13T04:26:11Z					biological_process											owl:Class	
GO:0072376	biolink:NamedThing	protein activation cascade	A response to a stimulus that consists of a sequential series of modifications to a set of proteins where the product of one reaction acts catalytically in the following reaction. The magnitude of the response is typically amplified at each successive step in the cascade. Modifications typically include proteolysis or covalent modification, and may also include binding events.	tmpzr1t_l9r_go_relaxed.owl	protein activitory cascade|protein activation pathway							mah	2010-11-22T02:54:18Z					biological_process											owl:Class	
GO:0051613	biolink:NamedThing	positive regulation of serotonin uptake	Any process that activates or increases the frequency, rate or extent of the directed movement of serotonin into a cell.	tmpzr1t_l9r_go_relaxed.owl	up regulation of serotonin uptake|stimulation of serotonin uptake|up-regulation of serotonin uptake|activation of serotonin uptake|positive regulation of 5-HT uptake|upregulation of serotonin uptake|positive regulation of 5HT uptake|positive regulation of serotonin import|positive regulation of 5-hydroxytryptamine uptake													biological_process											owl:Class	
GO:0043199	biolink:NamedThing	sulfate binding	Binding to sulfate, SO4(2-), a negatively charged small molecule.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0099589	biolink:NamedThing	serotonin receptor activity	Combining with the biogenic amine serotonin and transmitting a signal across a membrane by activating some effector activity. Serotonin (5-hydroxytryptamine) is a neurotransmitter and hormone found in vertebrates and invertebrates.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0031380	biolink:NamedThing	nuclear RNA-directed RNA polymerase complex	A complex required for RNAi mediated heterochromatin assembly. In S. pombe this contains RNA-directed RNA polymerase, a putative helicase and a protein containing a pap25 associated domain.	tmpzr1t_l9r_go_relaxed.owl	RDRC|Rdr1 complex													cellular_component											owl:Class	
GO:0032474	biolink:NamedThing	otolith morphogenesis	The process in which the anatomical structures of an otolith are generated and organized.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0101012	biolink:NamedThing	inositol 1,5-bisdiphosphate 2,3,4,6-tetrakisphosphate 1-diphosphatase activity	Catalysis of the reaction: myo-inositol 1,5-bisdiphosphate 2,3,4,6-tetrakisphosphate + H2O = myo-inositol 5-diphosphate 1,2,3,4,6-pentakisphosphate + phosphate.	tmpzr1t_l9r_go_relaxed.owl	inositol 1,5-bispyrophosphate 2,3,4,6-tetrakisphosphate 1-pyrophosphatase activity													molecular_function											owl:Class	
GO:1905157	biolink:NamedThing	positive regulation of photosynthesis	Any process that activates or increases the frequency, rate or extent of photosynthesis.	tmpzr1t_l9r_go_relaxed.owl	upregulation of photosynthesis|activation of photosynthesis|up regulation of photosynthesis|up-regulation of photosynthesis							tb	2016-04-19T16:12:39Z					biological_process											owl:Class	
GO:0001537	biolink:NamedThing	N-acetylgalactosamine 4-O-sulfotransferase activity	Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + N-acetyl-D-galactosamine = adenosine 3',5'-bisphosphate + N-acetyl-D-galactosamine 4-sulfate.	tmpzr1t_l9r_go_relaxed.owl	N-acetylgalactosamine 4-O-sulphotransferase activity				Reactome:R-HSA-3636919|Reactome:R-HSA-2022063|Reactome:R-HSA-6786034									molecular_function											owl:Class	
GO:2000703	biolink:NamedThing	negative regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation	Any process that stops, prevents or reduces the frequency, rate or extent of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of fibroblast growth factor receptor signaling pathway of ureteric bud formation|negative regulation of FGF receptor signaling pathway of ureteric bud formation|negative regulation of fibroblast growth factor receptor signalling pathway of ureteric bud formation|negative regulation of FGFR signaling pathway of ureteric bud formation|negative regulation of FGF receptor signalling pathway of ureteric bud formation							yaf	2011-05-25T09:48:22Z					biological_process											owl:Class	
GO:0002027	biolink:NamedThing	regulation of heart rate	Any process that modulates the frequency or rate of heart contraction.	tmpzr1t_l9r_go_relaxed.owl	regulation of heart contraction rate|cardiac chronotropy|regulation of rate of heart contraction													biological_process											owl:Class	
GO:0015195	biolink:NamedThing	L-threonine transmembrane transporter activity	Enables the transfer of L-threonine from one side of a membrane to the other. L-threonine is (2R*,3S*)-2-amino-3-hydroxybutanoic acid.	tmpzr1t_l9r_go_relaxed.owl	threonine/serine:sodium symporter activity|L-threonine permease activity|L-threonine transporter activity											GO:0015512		molecular_function											owl:Class	
GO:0010839	biolink:NamedThing	negative regulation of keratinocyte proliferation	Any process that decreases the rate, frequency or extent of keratinocyte proliferation. Keratinocyte proliferation is the multiplication or reproduction of keratinocytes, resulting in the expansion of a cell population.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0001989	biolink:NamedThing	positive regulation of the force of heart contraction involved in baroreceptor response to decreased systemic arterial blood pressure	Any process that increases the force with which the cardiac muscles of the heart pump blood through the circulatory system as part of the baroreceptor response to decreased blood pressure.	tmpzr1t_l9r_go_relaxed.owl	increased strength of cardiac contraction during baroreceptor response to decreased blood pressure|positive regulation of the force of heart contraction during baroreceptor response to decreased systemic arterial blood pressure|increased force of heart contraction during baroreceptor response to decreased systemic arterial blood pressure													biological_process											owl:Class	
GO:1904989	biolink:NamedThing	positive regulation of endothelial cell activation	Any process that activates or increases the frequency, rate or extent of endothelial cell activation.	tmpzr1t_l9r_go_relaxed.owl	upregulation of endothelial cell activation|up-regulation of endothelial cell activation|up regulation of endothelial cell activation|activation of endothelial cell activation							bc	2016-02-29T16:16:25Z					biological_process											owl:Class	
GO:0008180	biolink:NamedThing	COP9 signalosome	A protein complex that catalyzes the deneddylation of proteins, including the cullin component of SCF ubiquitin E3 ligase; deneddylation increases the activity of cullin family ubiquitin ligases. The signalosome is involved in many regulatory process, including some which control development, in many species; also regulates photomorphogenesis in plants; in many species its subunits are highly similar to those of the proteasome.	tmpzr1t_l9r_go_relaxed.owl	CSN|COP9 complex|signalosome													cellular_component											owl:Class	
GO:0071422	biolink:NamedThing	succinate transmembrane transport	The process in which succinate is transported across a membrane.	tmpzr1t_l9r_go_relaxed.owl	transmembrane succinate transport|succinate membrane transport					Note that this term is not intended for use in annotating lateral movement within membranes.		mah	2009-12-15T03:29:44Z					biological_process											owl:Class	
GO:0015744	biolink:NamedThing	succinate transport	The directed movement of succinate, the dianion of ethane dicarboxylic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0110156	biolink:NamedThing	methylguanosine-cap decapping	Cleavage of the 5'-methylguanosine-cap of an mRNA. The methylguanosine-cap is present at the 5'-end of eukaryotic mRNAs. Decapping inactivates translation initiation and promotes 5'-to-3' decay of mRNA.	tmpzr1t_l9r_go_relaxed.owl								kmv	2019-07-08T17:31:07Z					biological_process											owl:Class	
GO:0102447	biolink:NamedThing	rhamnetin 3'-O-methyltransferase activity	Catalysis of the reaction: rhamnetin + S-adenosyl-L-methionine  <=> 7,3'-dimethylquercetin + S-adenosyl-L-homocysteine  + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-13933									molecular_function											owl:Class	
GO:1903337	biolink:NamedThing	positive regulation of vacuolar transport	Any process that activates or increases the frequency, rate or extent of vacuolar transport.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of vacuolar transport|activation of vacuolar transport|upregulation of vacuolar transport|up regulation of vacuolar transport							vw	2014-08-18T13:16:19Z					biological_process											owl:Class	
GO:0030559	biolink:NamedThing	rRNA pseudouridylation guide activity	Specifies the site of pseudouridylation in an rRNA molecule by base pairing with a short sequence around the target residue.	tmpzr1t_l9r_go_relaxed.owl						Note that this term describes the activity of a nucleic acid, usually RNA, gene product that interacts with other RNA molecules via base pairing; it should not be used to annotate proteins.								molecular_function											owl:Class	
GO:0030558	biolink:NamedThing	RNA pseudouridylation guide activity	Specifies the site of pseudouridylation in an RNA molecule by base pairing with a short sequence around the target residue.	tmpzr1t_l9r_go_relaxed.owl						Note that this term describes the activity of a nucleic acid, usually RNA, gene product that interacts with other RNA molecules via base pairing; it should not be used to annotate proteins.								molecular_function											owl:Class	
GO:0031571	biolink:NamedThing	mitotic G1 DNA damage checkpoint signaling	A signal transduction process that contributes to a mitotic cell cycle G1/S transition DNA damage checkpoint.	tmpzr1t_l9r_go_relaxed.owl	intracellular signaling cascade involved in G1 DNA damage checkpoint|intracellular signaling chain involved in G1/S DNA damage checkpoint|intracellular signaling pathway involved in G1 DNA damage checkpoint|signal transduction via intracellular signaling cascade involved in G1/S DNA damage checkpoint|signal transduction involved in mitotic G1 DNA damage checkpoint|intracellular signaling cascade involved in G1/S DNA damage checkpoint|signal transduction involved in mitotic cell cycle G1/S transition DNA damage checkpoint|intracellular signal transduction pathway involved in G1 DNA damage checkpoint|mitotic G1 DNA damage checkpoint|G1 DNA damage checkpoint|intracellular signal transduction involved in G1 DNA damage checkpoint|signal transduction via intracellular signaling cascade involved in G1 DNA damage checkpoint|intracellular signal transduction pathway involved in G1/S DNA damage checkpoint|intracellular signaling chain involved in G1 DNA damage checkpoint|signal transmission via intracellular cascade involved in G1 DNA damage checkpoint|mitotic cell cycle G1/S transition DNA damage checkpoint|intracellular signaling pathway involved in G1/S DNA damage checkpoint|intracellular signal transduction involved in G1/S DNA damage checkpoint|G1/S DNA damage checkpoint											GO:0044783|GO:1902400|GO:0072431		biological_process											owl:Class	
GO:0045190	biolink:NamedThing	isotype switching	The switching of activated B cells from IgM biosynthesis to biosynthesis of other isotypes of immunoglobulin, accomplished through a recombination process involving an intrachromosomal deletion involving switch regions that reside 5' of each constant region gene segment in the immunoglobulin heavy chain locus.	tmpzr1t_l9r_go_relaxed.owl	class switching|class switch recombination|isotype switch recombination				Wikipedia:Immunoglobulin_class_switching	Note that IgM and IgD can be coexpressed by B cells via an alternate splicing mechanism, but true recombinational isotype switching to IgD has been demonstrated as well. Note that this term is best used to annotate gene products which are involved in the mechanism of DNA recombination used in isotype switching, like the B cell specific Swap70 factor in the mouse, rather than gene products which promote isotype switching such as cytokines or co-stimulatory molecules, which should instead be annotated to 'regulation of isotype switching ; GO:0045191'.								biological_process											owl:Class	
GO:0002312	biolink:NamedThing	B cell activation involved in immune response	The change in morphology and behavior of a mature or immature B cell during an immune response, resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.	tmpzr1t_l9r_go_relaxed.owl	B lymphocyte activation during immune response|B cell activation during immune response|B-cell activation during immune response|B-lymphocyte activation during immune response													biological_process											owl:Class	
GO:0046199	biolink:NamedThing	cresol catabolic process	The chemical reactions and pathways resulting in the breakdown of cresol, a mixture of the aromatic alcohol isoforms o-, p-, and m-cresol, which is obtained from coal tar or petroleum. The isomers are used as disinfectants, textile scouring agents, surfactants and as intermediates in the manufacture of salicylaldehyde, coumarin, and herbicides as well as being a major component of creosote.	tmpzr1t_l9r_go_relaxed.owl	cresol degradation|cresol breakdown|cresol catabolism													biological_process											owl:Class	
GO:1901072	biolink:NamedThing	glucosamine-containing compound catabolic process	The chemical reactions and pathways resulting in the breakdown of glucosamine-containing compounds (glucosamines).	tmpzr1t_l9r_go_relaxed.owl	glucosamine-containing compound breakdown|glucosamines breakdown|glucosamines catabolic process|glucosamine-containing compound catabolism|glucosamine-containing compound degradation|glucosamines degradation|glucosamines catabolism							bf	2012-07-02T03:18:25Z					biological_process											owl:Class	
GO:0032531	biolink:NamedThing	regulation of follicle cell microvillus organization	Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a microvillus on a follicle cell.	tmpzr1t_l9r_go_relaxed.owl	regulation of follicle cell microvillus organization and biogenesis|regulation of follicle cell microvillus organisation													biological_process											owl:Class	
GO:0009394	biolink:NamedThing	2'-deoxyribonucleotide metabolic process	The chemical reactions and pathways involving a 2'-deoxyribonucleotide, a compound consisting of 2'-deoxyribonucleoside (a base linked to a 2'-deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.	tmpzr1t_l9r_go_relaxed.owl	2'-deoxyribonucleotide metabolism													biological_process											owl:Class	
GO:0009262	biolink:NamedThing	deoxyribonucleotide metabolic process	The chemical reactions and pathways involving a deoxyribonucleotide, a compound consisting of deoxyribonucleoside (a base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.	tmpzr1t_l9r_go_relaxed.owl	deoxyribonucleotide metabolism											GO:0009122|GO:0009393		biological_process											owl:Class	
GO:0047862	biolink:NamedThing	diisopropyl-fluorophosphatase activity	Catalysis of the reaction: diisopropyl fluorophosphate + H(2)O = diisopropyl phosphate + 2 H(+) + hydrogen fluoride.	tmpzr1t_l9r_go_relaxed.owl	diisopropyl phosphorofluoridate hydrolase activity|OPAA activity|diisopropylfluorophosphonate dehalogenase activity|somanase activity|diisopropylphosphofluoridase activity|organophosphorus acid anhydrolase activity|dialkylfluorophosphatase activity|organophosphate acid anhydrase activity|isopropylphosphorofluoridase activity|diisopropyl-fluorophosphate fluorohydrolase activity|tabunase activity|DFPase activity|OPA anhydrase activity				MetaCyc:DIISOPROPYL-FLUOROPHOSPHATASE-RXN|KEGG_REACTION:R01533|RHEA:24100|EC:3.1.8.2									molecular_function											owl:Class	
GO:0016795	biolink:NamedThing	phosphoric triester hydrolase activity	Catalysis of the hydrolysis of a phosphoric triester.	tmpzr1t_l9r_go_relaxed.owl					EC:3.1.8.-									molecular_function											owl:Class	
GO:0045069	biolink:NamedThing	regulation of viral genome replication	Any process that modulates the frequency, rate or extent of viral genome replication.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0061122	biolink:NamedThing	positive regulation of positive chemotaxis to cAMP	Any process that increases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-05-17T08:25:55Z					biological_process											owl:Class	
GO:0030047	biolink:NamedThing	actin modification	Covalent modification of an actin molecule.	tmpzr1t_l9r_go_relaxed.owl												GO:0007013		biological_process											owl:Class	
GO:1903442	biolink:NamedThing	response to lipoic acid	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipoic acid stimulus.	tmpzr1t_l9r_go_relaxed.owl								jl	2014-09-17T13:52:03Z					biological_process											owl:Class	
GO:0022022	biolink:NamedThing	septal cell proliferation	The multiplication or reproduction of septal cells, resulting in the expansion of a cell population.	tmpzr1t_l9r_go_relaxed.owl	septum cell proliferation													biological_process											owl:Class	
GO:0098682	biolink:NamedThing	arciform density	An electron dense structure that anchors a synaptic ribbon to the presynaptic membrane.	tmpzr1t_l9r_go_relaxed.owl								dos	2017-02-05T16:12:22Z					cellular_component											owl:Class	
GO:0071219	biolink:NamedThing	cellular response to molecule of bacterial origin	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by molecules of bacterial origin such as peptides derived from bacterial flagellin.	tmpzr1t_l9r_go_relaxed.owl	cellular response to bacteria associated molecule|cellular response to bacterial associated molecule|cellular response to bacterium associated molecule							mah	2009-12-03T01:22:00Z					biological_process											owl:Class	
GO:0010270	biolink:NamedThing	photosystem II oxygen evolving complex assembly	The aggregation, arrangement and bonding together of a set of components to form the oxygen evolving complex (OEC) of photosystem II on a thylakoid membrane. The OEC protects the calcium-4 manganese-5 oxide cluster which is bound to the D1 and CP43 proteins. The exact protein composition of the OEC varies between cyanobacteria and plants, and in plants consists of three extrinsic nuclear-encoded polypeptides: PsbO, PsbP and PsbQ.	tmpzr1t_l9r_go_relaxed.owl	OEC (PSII) ASSEMBLY													biological_process											owl:Class	
GO:0010207	biolink:NamedThing	photosystem II assembly	The aggregation, arrangement and bonding together of a set of components to form a photosystem II complex on the thylakoid membrane. The photosystem II complex consists of at least 20 polypeptides and around 80 cofactors in most organisms.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0002409	biolink:NamedThing	Langerhans cell chemotaxis	The movement of a Langerhans cell in response to an external stimulus.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0061411	biolink:NamedThing	positive regulation of transcription from RNA polymerase II promoter in response to cold	Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that organism.	tmpzr1t_l9r_go_relaxed.owl								dph	2012-01-12T12:31:33Z					biological_process											owl:Class	
GO:1903745	biolink:NamedThing	negative regulation of pharyngeal pumping	Any process that stops, prevents or reduces the frequency, rate or extent of pharyngeal pumping.	tmpzr1t_l9r_go_relaxed.owl	down regulation of pharyngeal pumping|inhibition of pumping behavior|down-regulation of pumping behavior|downregulation of pharyngeal pumping|down regulation of pumping behavior|downregulation of pumping behavior|down-regulation of pharyngeal pumping|negative regulation of pumping behavior|inhibition of pharyngeal pumping							kmv	2014-12-12T17:10:59Z					biological_process											owl:Class	
GO:0048209	biolink:NamedThing	regulation of vesicle targeting, to, from or within Golgi	Any process that modulates the frequency, rate, or destination of vesicle-mediated transport to, from or within the Golgi apparatus.	tmpzr1t_l9r_go_relaxed.owl	regulation of Golgi vesicle targeting													biological_process											owl:Class	
GO:0046159	biolink:NamedThing	ocellus pigment catabolic process	The chemical reactions and pathways resulting in the breakdown of ocellus pigments, any general or particular coloring matter in living organisms, found or utilized in the ocellus, a minute simple eye found in many invertebrates.	tmpzr1t_l9r_go_relaxed.owl	ocellus pigment catabolism|ocellus pigment degradation|ocellus pigment breakdown													biological_process											owl:Class	
GO:0010418	biolink:NamedThing	rhamnogalacturonan II backbone metabolic process	The chemical reactions and pathways involving the backbone structure of pectic rhamnogalacturonan II. The back bone contains at least 8 1,4-linked alpha-D-GalpA residues.	tmpzr1t_l9r_go_relaxed.owl	rhamnogalacturonan II backbone metabolism													biological_process											owl:Class	
GO:0010394	biolink:NamedThing	homogalacturonan metabolic process	The chemical reactions and pathways involving homogalacturonan, a pectin characterized by a backbone of alpha-(1->4)-linked D-galacturonic acid residues that can be methyl-esterified at C-6 and carry acetyl groups on O-2 and O-3.	tmpzr1t_l9r_go_relaxed.owl	homogalacturonan metabolism													biological_process											owl:Class	
GO:0047686	biolink:NamedThing	arylsulfate sulfotransferase activity	Catalysis of the reaction: an aryl sulfate + a phenol = a phenol + an aryl sulfate.	tmpzr1t_l9r_go_relaxed.owl	ASST|arylsulphate sulphotransferase activity|arylsulfotransferase|arylsulfate:phenol sulfotransferase activity|arylsulfate-phenol sulfotransferase activity				RHEA:51072|EC:2.8.2.22|MetaCyc:ARYLSULFATE-SULFOTRANSFERASE-RXN									molecular_function											owl:Class	
GO:1905672	biolink:NamedThing	negative regulation of lysosome organization	Any process that stops, prevents or reduces the frequency, rate or extent of lysosome organization.	tmpzr1t_l9r_go_relaxed.owl	down regulation of lysosome organization and biogenesis|down regulation of lysosome organisation|downregulation of lysosome organisation|down-regulation of lysosome organization and biogenesis|inhibition of lysosome organization|negative regulation of lysosome organisation|downregulation of lysosome organization and biogenesis|downregulation of lysosome organization|inhibition of lysosome organization and biogenesis|inhibition of lysosome organisation|down-regulation of lysosome organization|negative regulation of lysosome organization and biogenesis|down-regulation of lysosome organisation|down regulation of lysosome organization							sl	2016-11-11T22:01:12Z					biological_process											owl:Class	
GO:2000612	biolink:NamedThing	regulation of thyroid-stimulating hormone secretion	Any process that modulates the frequency, rate or extent of thyroid-stimulating hormone secretion.	tmpzr1t_l9r_go_relaxed.owl	regulation of thyroid stimulating hormone secretion|regulation of TSH secretion							yaf	2011-04-18T12:56:16Z					biological_process											owl:Class	
GO:1905276	biolink:NamedThing	regulation of epithelial tube formation	Any process that modulates the frequency, rate or extent of epithelial tube formation.	tmpzr1t_l9r_go_relaxed.owl						An example of this is MMRN2 in human (Q9H8L6) in PMID:25745997 (inferred from direct assay).		bhm	2016-06-20T09:35:41Z					biological_process											owl:Class	
GO:0004342	biolink:NamedThing	glucosamine-6-phosphate deaminase activity	Catalysis of the reaction: D-glucosamine 6-phosphate + H(2)O = beta-D-fructose 6-phosphate + NH(4)(+).	tmpzr1t_l9r_go_relaxed.owl	glucosamine phosphate deaminase activity|glucosaminephosphate isomerase|phosphoglucosamine isomerase activity|phosphoglucosaminisomerase activity|GlcN6P deaminase activity|glucosamine-6-phosphate isomerase activity|aminodeoxyglucosephosphate isomerase activity|2-amino-2-deoxy-D-glucose-6-phosphate aminohydrolase (ketol isomerizing)				EC:3.5.99.6|Reactome:R-HSA-6799604|RHEA:12172|MetaCyc:GLUCOSAMINE-6-P-DEAMIN-RXN|KEGG_REACTION:R00765	Note that this function was formerly EC:5.3.1.10.								molecular_function											owl:Class	
GO:0030120	biolink:NamedThing	vesicle coat	A membrane coat found on a coated vesicle.	tmpzr1t_l9r_go_relaxed.owl					NIF_Subcellular:sao1177708494									cellular_component											owl:Class	
GO:0110082	biolink:NamedThing	regulation of protein localization to cell division site involved in mitotic actomyosin contractile ring assembly	Any process that modulates the frequency, rate or extent of protein localization to cell division site involved in mitotic actomyosin contractile ring assembly.	tmpzr1t_l9r_go_relaxed.owl								kmv	2018-02-01T19:25:06Z					biological_process											owl:Class	
GO:0003240	biolink:NamedThing	conus arteriosus formation	The developmental process pertaining to the initial formation of the conus arteriosus from unspecified parts. The conus arteriosus is a valved chamber with thick muscular walls stemming from the ventricle and connecting to the pulmonary trunk.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-10-13T11:25:47Z					biological_process											owl:Class	
GO:0003207	biolink:NamedThing	cardiac chamber formation	The developmental process pertaining to the initial formation of a cardiac chamber from unspecified parts. A cardiac chamber is an enclosed cavity within the heart.	tmpzr1t_l9r_go_relaxed.owl	heart chamber formation							dph	2009-10-13T09:29:13Z					biological_process											owl:Class	
GO:0033743	biolink:NamedThing	peptide-methionine (R)-S-oxide reductase activity	Catalysis of the reaction: peptide-L-methionine + H(2)O + thioredoxin disulfide = peptide-L-methionine (R)-S-oxide + thioredoxin. Can act on oxidized methionine in peptide linkage with specificity for the R enantiomer. Thioredoxin disulfide is the oxidized form of thioredoxin.	tmpzr1t_l9r_go_relaxed.owl	methionine S-oxide reductase (R-form oxidizing) activity|protein-methionine-R-oxide reductase activity|PilB|methionine sulfoxide reductase B activity|methionine sulfoxide reductase activity|selenoprotein R|pMSR|MsrB|SelR|methionine S-oxide reductase activity|pMRsr|peptide-methionine:thioredoxin-disulfide S-oxidoreductase [methionine (R)-S-oxide-forming] activity|SelX				MetaCyc:1.8.4.12-RXN|EC:1.8.4.12|Reactome:R-HSA-5676917|RHEA:24164|KEGG_REACTION:R07607							GO:0000318		molecular_function											owl:Class	
GO:1901845	biolink:NamedThing	negative regulation of cell communication by electrical coupling involved in cardiac conduction	Any process that stops, prevents or reduces the frequency, rate or extent of cell communication by electrical coupling involved in cardiac conduction.	tmpzr1t_l9r_go_relaxed.owl	down regulation of cell communication by electrical coupling involved in cardiac conduction|down-regulation of cell communication by electrical coupling involved in cardiac conduction|downregulation of cell communication by electrical coupling involved in cardiac conduction|inhibition of cell communication by electrical coupling involved in cardiac conduction							rl	2013-01-24T19:15:44Z					biological_process											owl:Class	
GO:0102240	biolink:NamedThing	soyasapogenol B glucuronide galactosyltransferase activity	Catalysis of the reaction: UDP-D-galactose + soyasapogenol B 3-O-beta-glucuronate <=> H+ + UDP + soyasaponin III.	tmpzr1t_l9r_go_relaxed.owl					RHEA:31487|MetaCyc:RXN-12319|EC:2.4.1.272									molecular_function											owl:Class	
GO:0010317	biolink:NamedThing	pyrophosphate-dependent phosphofructokinase complex, alpha-subunit complex	Refers to the alpha subunit of the heterodimeric complex that possesses pyrophosphate-dependent phosphofructokinase activity.	tmpzr1t_l9r_go_relaxed.owl	PFK complex, alpha-subunit													cellular_component											owl:Class	
GO:0047604	biolink:NamedThing	acetoin racemase activity	Catalysis of the reaction: (S)-acetoin = (R)-acetoin.	tmpzr1t_l9r_go_relaxed.owl	acetylmethylcarbinol racemase activity				EC:5.1.2.4|KEGG_REACTION:R02949|RHEA:12092|MetaCyc:ACETOIN-RACEMASE-RXN									molecular_function											owl:Class	
GO:0097108	biolink:NamedThing	hedgehog family protein binding	Binding to a member of the hedgehog protein family, signaling proteins involved in development.	tmpzr1t_l9r_go_relaxed.owl								pr	2011-07-28T10:06:45Z					molecular_function											owl:Class	
GO:0010415	biolink:NamedThing	unsubstituted mannan metabolic process	The chemical reactions and pathways involving the mannan backbone, the unsubstituted polymer of D-mannose units.	tmpzr1t_l9r_go_relaxed.owl	unsubstituted mannan metabolism													biological_process											owl:Class	
GO:0010412	biolink:NamedThing	mannan metabolic process	The chemical reactions and pathways involving mannan, a group of polysaccharides containing a backbone composed of a polymer of D-mannose units.	tmpzr1t_l9r_go_relaxed.owl	mannan metabolism													biological_process											owl:Class	
GO:0061189	biolink:NamedThing	positive regulation of sclerotome development	Any process that increases the rate, frequency, or extent of the progression of the sclerotome over time, from its initial formation to the mature structure. The sclerotome is the portion of the somite that will give rise to a vertebra.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-07-14T09:17:23Z					biological_process											owl:Class	
GO:0061190	biolink:NamedThing	regulation of sclerotome development	Any process that modulates the rate, frequency, or extent of the progression of the sclerotome over time, from its initial formation to the mature structure. The sclerotome is the portion of the somite that will give rise to a vertebra.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-07-14T09:19:47Z					biological_process											owl:Class	
GO:0047451	biolink:NamedThing	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity	Catalysis of the reaction: (3R)-3-hydroxyoctanoyl-[acyl-carrier protein] = H2O + 2-octenoyl-[acyl-carrier protein].	tmpzr1t_l9r_go_relaxed.owl	beta-hydroxyoctanoyl-acyl carrier protein dehydrase activity|D-3-hydroxyoctanoyl-[acyl carrier protein] dehydratase activity|3-hydroxyoctanoyl-ACP dehydratase activity|3-hydroxyoctanoyl-[acyl-carrier protein] dehydratase activity|D-3-hydroxyoctanoyl-acyl carrier protein dehydratase activity|(3R)-3-hydroxyoctanoyl-[acyl-carrier-protein] hydro-lyase activity|(3R)-3-hydroxyoctanoyl-acyl-carrier-protein hydro-lyase (oct-2-enoyl-acyl-carrier protein-forming)|3-hydroxyoctanoyl-acyl-carrier-protein dehydratase activity|beta-hydroxyoctanoyl-ACP-dehydrase activity|(3R)-3-hydroxyoctanoyl-acyl-carrier-protein hydro-lyase activity|beta-hydroxyoctanoyl thioester dehydratase activity				RHEA:41844|KEGG_REACTION:R04537|EC:4.2.1.59|MetaCyc:4.2.1.59-RXN									molecular_function											owl:Class	
GO:0002227	biolink:NamedThing	innate immune response in mucosa	Any process of the innate immune response that takes place in the mucosal tissues.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0047778	biolink:NamedThing	[citrate-(pro-3S)-lyase] thiolesterase activity	Catalysis of the reaction: [citrate (pro-3S)-lyase](acetyl form) + H2O = [citrate (pro-3S)-lyase](thiol form) + acetate.	tmpzr1t_l9r_go_relaxed.owl	citrate-(pro-3S)-lyase thiolesterase activity|citrate-(pro-3S)-lyase(acetyl-form) hydrolase activity|citrate lyase deacetylase activity|[citrate-(pro-3S)-lyase] thioesterase activity|citrate (pro-3S)-lyase thiolesterase activity|citrate-(pro-3S)-lyase thioesterase activity				MetaCyc:CITRATE-PRO-3S-LYASE-THIOLESTERASE-RXN|RHEA:13657|EC:3.1.2.16									molecular_function											owl:Class	
GO:0051710	biolink:NamedThing	regulation of cytolysis in other organism	Any process that modulates the frequency, rate or extent of the cytolysis by an organism of cells in another organism.	tmpzr1t_l9r_go_relaxed.owl	regulation of cytolysis of cells of another organism|regulation of cytolysis of cells of another, non-host, organism											GO:0001902		biological_process											owl:Class	
GO:0042268	biolink:NamedThing	regulation of cytolysis	Any process that modulates the frequency, rate or extent of the rupture of cell membranes and the loss of cytoplasm.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1903629	biolink:NamedThing	positive regulation of dUTP diphosphatase activity	Any process that activates or increases the frequency, rate or extent of dUTP diphosphatase activity.	tmpzr1t_l9r_go_relaxed.owl	activation of dUTP diphosphatase activity|up-regulation of dUTPase activity|activation of deoxyuridine-triphosphatase activity|activation of dUTP nucleotidohydrolase activity|up-regulation of deoxyuridine-triphosphatase activity|upregulation of dUTP pyrophosphatase activity|positive regulation of dUTPase activity|positive regulation of desoxyuridine 5'-triphosphatase activity|activation of desoxyuridine 5'-triphosphatase activity|up-regulation of dUTP diphosphatase activity|positive regulation of dUTP nucleotidohydrolase activity|up regulation of dUTPase activity|up-regulation of dUTP nucleotidohydrolase activity|upregulation of dUTPase activity|activation of desoxyuridine 5'-triphosphate nucleotidohydrolase activity|up regulation of dUTP nucleotidohydrolase activity|upregulation of dUTP nucleotidohydrolase activity|upregulation of dUTP diphosphatase activity|up regulation of desoxyuridine 5'-triphosphate nucleotidohydrolase activity|upregulation of desoxyuridine 5'-triphosphatase activity|up regulation of desoxyuridine 5'-triphosphatase activity|positive regulation of deoxyuridine-triphosphatase activity|up regulation of deoxyuridine-triphosphatase activity|up-regulation of desoxyuridine 5'-triphosphatase activity|up regulation of dUTP pyrophosphatase activity|upregulation of desoxyuridine 5'-triphosphate nucleotidohydrolase activity|positive regulation of desoxyuridine 5'-triphosphate nucleotidohydrolase activity|positive regulation of dUTP pyrophosphatase activity|up-regulation of desoxyuridine 5'-triphosphate nucleotidohydrolase activity|activation of dUTP pyrophosphatase activity|upregulation of deoxyuridine-triphosphatase activity|up regulation of dUTP diphosphatase activity|activation of dUTPase activity|up-regulation of dUTP pyrophosphatase activity							sl	2014-11-20T00:00:56Z					biological_process											owl:Class	
GO:0046745	biolink:NamedThing	viral capsid secondary envelopment	The process in which a capsid acquires another membrane envelope, subsequent to acquiring an initial membrane envelope.	tmpzr1t_l9r_go_relaxed.owl	virus budding from ER membrane by viral capsid re-envelopment|endoplasmic reticulum membrane viral budding during viral capsid re-envelopment|plasma membrane viral budding during viral capsid re-envelopment|virus budding from Golgi membrane by viral capsid re-envelopment|viral budding from ER membrane during viral capsid re-envelopment|virus budding from plasma membrane during viral capsid re-envelopment|viral budding from nuclear membrane during viral capsid re-envelopment|viral budding from inner nuclear membrane by viral capsid re-envelopment|virus budding from outer nuclear membrane during viral capsid re-envelopment|ER membrane viral budding during viral capsid re-envelopment|virus budding from Golgi membrane during viral capsid re-envelopment|virus budding from ER membrane during viral capsid re-envelopment|viral budding from Golgi membrane by viral capsid re-envelopment|viral budding from inner nuclear membrane during viral capsid re-envelopment|nuclear membrane viral budding during viral capsid re-envelopment|viral budding from nuclear membrane by viral capsid re-envelopment|viral budding from outer nuclear membrane during viral capsid re-envelopment|virus budding from inner nuclear membrane by viral capsid re-envelopment|virus budding from nuclear membrane by viral capsid re-envelopment|viral budding from Golgi membrane during viral capsid re-envelopment|Golgi membrane viral budding during viral capsid re-envelopment|virus budding from inner nuclear membrane during viral capsid re-envelopment|outer nuclear membrane viral budding during viral capsid re-envelopment|viral budding from outer nuclear membrane by viral capsid re-envelopment|viral budding from plasma membrane during viral capsid re-envelopment|viral capsid re-envelopment|viral budding from ER membrane by viral capsid re-envelopment|inner nuclear membrane viral budding during viral capsid re-envelopment|virus budding from nuclear membrane during viral capsid re-envelopment|viral budding from plasma membrane by viral capsid re-envelopment|virus budding from outer nuclear membrane by viral capsid re-envelopment											GO:0046748|GO:0046747|GO:0046746|GO:0046769|GO:0046768|GO:0046770		biological_process											owl:Class	
GO:0033506	biolink:NamedThing	glucosinolate biosynthetic process from homomethionine	The chemical reactions and pathways resulting in the formation of glucosinolates from other compounds including homomethionine.	tmpzr1t_l9r_go_relaxed.owl	glucosinolate formation from homomethionine|glucosinolate anabolism from homomethionine|glucosinolate synthesis from homomethionine|glucosinolate biosynthesis from homomethionine				MetaCyc:PWY-1187									biological_process											owl:Class	
GO:0016319	biolink:NamedThing	mushroom body development	The process whose specific outcome is the progression of the mushroom body over time, from its formation to the mature structure. The mushroom body is composed of the prominent neuropil structures of the insect central brain, thought to be crucial for olfactory associated learning. These consist mainly of a bulbous calyx and tightly packaged arrays of thin parallel fibers of the Kenyon cells.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:2000342	biolink:NamedThing	negative regulation of chemokine (C-X-C motif) ligand 2 production	Any process that stops, prevents or reduces the frequency, rate or extent of chemokine (C-X-C motif) ligand 2 production.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of SCYB2 production|negative regulation of MIP-2 production|inhibition of chemokine (C-C motif) ligand 2 secretion|inhibition of CCL2 secretion|negative regulation of CXCL2 production|negative regulation of chemokine (C-C motif) ligand 2 secretion|negative regulation of MIP2 production							mah	2011-02-01T11:57:17Z			GO:1904208		biological_process											owl:Class	
GO:0035244	biolink:NamedThing	peptidyl-arginine C-methyltransferase activity	Catalysis of the transfer of a methyl group to the carbon atom of an arginine residue in a protein.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0004666	biolink:NamedThing	prostaglandin-endoperoxide synthase activity	Catalysis of the reaction: arachidonate + donor-H2 + 2 O2 = prostaglandin H2 + acceptor + H2O.	tmpzr1t_l9r_go_relaxed.owl	prostaglandin synthetase activity|fatty acid cyclooxygenase activity|prostaglandin synthase activity|prostaglandin G/H synthase activity|(PG)H synthase activity|PG synthetase activity|(5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoate,hydrogen-donor:oxygen oxidoreductase activity|prostaglandin endoperoxide synthetase activity				RHEA:23728|Reactome:R-HSA-140355|EC:1.14.99.1|MetaCyc:PROSTAGLANDIN-ENDOPEROXIDE-SYNTHASE-RXN|Reactome:R-HSA-2309787									molecular_function											owl:Class	
GO:0047223	biolink:NamedThing	beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity	Catalysis of the reaction: beta-D-galactosyl-1,3-(N-acetyl-D-glucosaminyl-1,6)-N-acetyl-D-galactosaminyl-R + UDP-N-acetyl-D-glucosamine = N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,3-(N-acetyl-beta-D-glucosaminyl-1,6)-N-acetyl-D-galactosaminyl-R + UDP.	tmpzr1t_l9r_go_relaxed.owl	elongation 3-beta-GalNAc-transferase activity|uridine diphosphoacetylglucosamine-mucin beta(1->3)-acetylglucosaminyltransferase (elongating)|O-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase II activity|elongation 3beta-GalNAc-transferase activity|UDP-N-acetyl-D-glucosamine:O-glycosyl-glycoprotein (N-acetyl-D-glucosamine to -D-galactose of beta-D-galactosyl-1,3-(N-acetyl-D-glucosaminyl-1,6)-N-acetyl-D-galactosaminyl-R) beta-1,3-N-acetyl-D-glucosaminyltransferase activity				Reactome:R-HSA-5617096|EC:2.4.1.146|MetaCyc:2.4.1.146-RXN|Reactome:R-HSA-5617037									molecular_function											owl:Class	
GO:0033162	biolink:NamedThing	melanosome membrane	The lipid bilayer surrounding a melanosome.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0032761	biolink:NamedThing	positive regulation of lymphotoxin A production	Any process that activates or increases the frequency, rate, or extent of lymphotoxin A production.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of lymphotoxin-alpha production|positive regulation of TNF-beta production|stimulation of lymphotoxin A production|positive regulation of LTA production|up-regulation of lymphotoxin A production|upregulation of lymphotoxin A production|activation of lymphotoxin A production|positive regulation of tumor necrosis factor-beta production|positive regulation of lymphotoxin A biosynthetic process|up regulation of lymphotoxin A production											GO:0043017		biological_process											owl:Class	
GO:1900697	biolink:NamedThing	positive regulation of N',N'',N'''-triacetylfusarinine C biosynthetic process	Any process that activates or increases the frequency, rate or extent of N',N'',N'''-triacetylfusarinine C biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of N',N'',N'''-triacetylfusarinine C synthesis|upregulation of N',N'',N'''-triacetylfusarinine C formation|upregulation of N',N'',N'''-triacetylfusarinine C biosynthesis|up regulation of N',N'',N'''-triacetylfusarinine C biosynthesis|activation of N',N'',N'''-triacetylfusarinine C anabolism|upregulation of N',N'',N'''-triacetylfusarinine C biosynthetic process|up regulation of N',N'',N'''-triacetylfusarinine C formation|activation of N',N'',N'''-triacetylfusarinine C biosynthesis|up regulation of N',N'',N'''-triacetylfusarinine C anabolism|positive regulation of N',N'',N'''-triacetylfusarinine C anabolism|up-regulation of N',N'',N'''-triacetylfusarinine C formation|up regulation of N',N'',N'''-triacetylfusarinine C biosynthetic process|activation of N',N'',N'''-triacetylfusarinine C biosynthetic process|up-regulation of N',N'',N'''-triacetylfusarinine C anabolism|positive regulation of N',N'',N'''-triacetylfusarinine C biosynthesis|positive regulation of N',N'',N'''-triacetylfusarinine C formation|activation of N',N'',N'''-triacetylfusarinine C synthesis|upregulation of N',N'',N'''-triacetylfusarinine C anabolism|upregulation of N',N'',N'''-triacetylfusarinine C synthesis|positive regulation of N',N'',N'''-triacetylfusarinine C synthesis|up-regulation of N',N'',N'''-triacetylfusarinine C biosynthetic process|up-regulation of N',N'',N'''-triacetylfusarinine C biosynthesis|activation of N',N'',N'''-triacetylfusarinine C formation|up regulation of N',N'',N'''-triacetylfusarinine C synthesis							di	2012-05-22T04:54:56Z					biological_process											owl:Class	
GO:0051873	biolink:NamedThing	killing by host of symbiont cells	Any process mediated by an organism that results in the death of cells in the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	disruption by host of symbiont cells	https://github.com/geneontology/go-ontology/issues/18719										GO:0051852		biological_process											owl:Class	
GO:0015690	biolink:NamedThing	aluminum cation transport	The directed movement of aluminum (Al) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	aluminium transport|aluminum transport|aluminium ion transport|aluminum ion transport													biological_process											owl:Class	
GO:0030001	biolink:NamedThing	metal ion transport	The directed movement of metal ions, any metal ion with an electric charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	divalent metal ion transport|heavy metal ion transport											GO:0070838		biological_process											owl:Class	
GO:0060702	biolink:NamedThing	negative regulation of endoribonuclease activity	Any process that decreases the rate, frequency or extent of the catalysis of the hydrolysis of ester linkages within ribonucleic acid by creating internal breaks.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-06-08T02:52:27Z					biological_process											owl:Class	
GO:0010562	biolink:NamedThing	positive regulation of phosphorus metabolic process	Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1901379	biolink:NamedThing	regulation of potassium ion transmembrane transport	Any process that modulates the frequency, rate or extent of potassium ion transmembrane transport.	tmpzr1t_l9r_go_relaxed.owl	regulation of potassium ion membrane transport							rl	2012-09-28T15:58:00Z					biological_process											owl:Class	
GO:0009421	biolink:NamedThing	bacterial-type flagellum filament cap	The proteinaceous structure at the distal tip of the bacterial-type flagellar filament.	tmpzr1t_l9r_go_relaxed.owl	flagellar filament cap|flagellin-based flagellum filament cap													cellular_component											owl:Class	
GO:1990715	biolink:NamedThing	mRNA CDS binding	Binding to an mRNA molecule coding sequence (CDS).	tmpzr1t_l9r_go_relaxed.owl	mRNA coding sequence binding|mRNA coding region binding							kmv	2015-03-27T20:59:49Z					molecular_function											owl:Class	
GO:0070726	biolink:NamedThing	cell wall assembly	The aggregation, arrangement and bonding together of a cell wall. A cell wall is a rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal, and most prokaryotic cells.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-06-16T03:58:20Z					biological_process											owl:Class	
GO:0046079	biolink:NamedThing	dUMP catabolic process	The chemical reactions and pathways resulting in the breakdown of dUMP, deoxyuridine (5'-)monophosphate.	tmpzr1t_l9r_go_relaxed.owl	dUMP breakdown|dUMP catabolism|dUMP degradation													biological_process											owl:Class	
GO:0061584	biolink:NamedThing	hypocretin secretion	The controlled release of hypocretin from a cell or a tissue.	tmpzr1t_l9r_go_relaxed.owl	orexin secretion							dph	2013-12-26T10:07:38Z					biological_process											owl:Class	
GO:0034933	biolink:NamedThing	1-hydroxy-6-methoxypyrene methyltransferase activity	Catalysis of the reaction: 1-hydroxy-6-methoxypyrene + XCH3 = 1,6-dimethoxypyrene + HX.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0956									molecular_function											owl:Class	
GO:0106101	biolink:NamedThing	ER-dependent peroxisome localization	A process in which a protein is transported to, or maintained at, a location in a peroxisome via the endoplasmic reticulum.	tmpzr1t_l9r_go_relaxed.owl								hjd	2018-02-15T17:54:20Z					biological_process											owl:Class	
GO:0072662	biolink:NamedThing	protein localization to peroxisome	A process in which a protein is transported to, or maintained at, a location in a peroxisome.	tmpzr1t_l9r_go_relaxed.owl	protein localisation to peroxisome							mah	2011-02-14T02:50:04Z					biological_process											owl:Class	
GO:0033474	biolink:NamedThing	indoleacetic acid conjugate biosynthetic process	The chemical reactions and pathways resulting in the formation of an indole-3-acetic acid conjugate, a form of indoleacetic acid covalently bound to another molecule.	tmpzr1t_l9r_go_relaxed.owl	indoleacetic acid conjugate formation|indoleacetic acid conjugate biosynthesis|indoleacetic acid conjugate anabolism|indole acetic acid conjugate biosynthesis|indoleacetic acid conjugate synthesis|IAA conjugate biosynthetic process|indole acetic acid conjugate biosynthetic process													biological_process											owl:Class	
GO:0090245	biolink:NamedThing	axis elongation involved in somitogenesis	The developmental growth that results in the elongation of the rostral-caudal axis that contributes to somitogenesis.	tmpzr1t_l9r_go_relaxed.owl								tb	2010-01-22T10:54:29Z					biological_process											owl:Class	
GO:0018157	biolink:NamedThing	peptide cross-linking via an oxazole or thiazole	The chemical reactions and pathways resulting in the formation of a peptidyl serine-peptidyl glycine, or peptidyl cysteine-peptidyl glycine cross-link by the condensation of the serine hydroxyl or cysteine thiol with the carbonyl of the preceding residue and alpha-beta dehydrogenation.	tmpzr1t_l9r_go_relaxed.owl	peptide heterocycle synthesis|peptide heterocycle biosynthesis|peptide heterocycle biosynthetic process|peptide heterocycle formation													biological_process											owl:Class	
GO:0060470	biolink:NamedThing	positive regulation of cytosolic calcium ion concentration involved in egg activation	The process that increases the concentration of calcium ions in the cytosol after fertilization or the physiological activation of an egg.	tmpzr1t_l9r_go_relaxed.owl	elevation of cytosolic calcium ion concentration involved in egg activation													biological_process											owl:Class	
GO:0047780	biolink:NamedThing	citrate dehydratase activity	Catalysis of the reaction: citrate = cis-aconitate + H2O.	tmpzr1t_l9r_go_relaxed.owl	citrate hydro-lyase (cis-aconitate-forming)|citrate hydro-lyase activity|aconitate hydratase activity|citrate hydro-lyase (cis-aconitate-forming) activity				EC:4.2.1.3|RHEA:10228|MetaCyc:CITRATE-DEHYDRATASE-RXN|MetaCyc:ACONITATEDEHYDR-RXN|KEGG_REACTION:R01325	This term is also a sub-reaction of 'aconitate hydratase activity ; GO:0003994 (EC:4.2.1.3)'.						GO:0052632		molecular_function											owl:Class	
GO:1990563	biolink:NamedThing	extracellular exosome complex	A protein complex that is wholly or partially contained within the lumen or membrane of the extracellular vesicular exosome.	tmpzr1t_l9r_go_relaxed.owl	exosome complex|extracellular vesicular exosome complex					An example of this is SCD1 in human (UniProt symbol P18827) in PMID:22660413 (inferred from physical interaction).		bhm	2014-11-25T16:35:53Z					cellular_component											owl:Class	
GO:0031153	biolink:NamedThing	slug development involved in sorocarp development	The process whose specific outcome is the progression of the slug over time, from its formation to the mature structure. Slug development begins when the aggregate rises upwards to form a finger-shaped structure and ends when culmination begins. Slug development begins after aggregation and ends before culmination in sorocarp development.	tmpzr1t_l9r_go_relaxed.owl	pseudoplasmodium biosynthesis|standing slug development during sorocarp development|migratory slug development during sorocarp development|slug development during sorocarp development|pseudoplasmodium formation|slug development during fruiting body development													biological_process											owl:Class	
GO:0099120	biolink:NamedThing	socially cooperative development	The process whose specific outcome is the progression of a non-reproductive fruiting body over time, from its formation to the mature structure. A non-reproductive fruiting body is a colonial multicellular structure consisting of co-operating unicellular organisms, some of which are  spores. An example of such a process is found in Dictyostelium discoideum and Myxococcus xanthus colonies.	tmpzr1t_l9r_go_relaxed.owl	colonial development|socially co-operative development|non-reproductive fruiting body development	https://github.com/geneontology/go-ontology/issues/20428										GO:0090702		biological_process											owl:Class	
GO:0048089	biolink:NamedThing	regulation of female pigmentation	Any process that modulates the frequency, rate or extent of establishment of a pattern of pigment in females.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1902724	biolink:NamedThing	positive regulation of skeletal muscle satellite cell proliferation	Any process that activates or increases the frequency, rate or extent of skeletal muscle satellite cell proliferation.	tmpzr1t_l9r_go_relaxed.owl	up regulation of satellite cell proliferation|upregulation of satellite cell proliferation|activation of satellite cell proliferation|up-regulation of satellite cell proliferation							mr	2014-02-24T16:09:56Z					biological_process											owl:Class	
GO:0014858	biolink:NamedThing	positive regulation of skeletal muscle cell proliferation	Any process that activates or increases the frequency, rate or extent of skeletal muscle cell proliferation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0071568	biolink:NamedThing	UFM1 transferase activity	Catalysis of the transfer of UFM1 from one protein to another via the reaction X-UFM1 + Y --> Y-UFM1 + X, where both X-UFM1 and Y-UFM1 are covalent linkages.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-01-20T04:10:11Z					molecular_function											owl:Class	
GO:0042201	biolink:NamedThing	N-cyclopropylmelamine metabolic process	The chemical reactions and pathways involving N-cyclopropylmelamine, a triazine compound commonly used as an insect growth regulator insecticide.	tmpzr1t_l9r_go_relaxed.owl	N-cyclopropylmelamine metabolism|cyromazine metabolic process|cyromazine metabolism													biological_process											owl:Class	
GO:0045017	biolink:NamedThing	glycerolipid biosynthetic process	The chemical reactions and pathways resulting in the formation of glycerolipids, any lipid with a glycerol backbone.	tmpzr1t_l9r_go_relaxed.owl	glycerolipid anabolism|glycerolipid synthesis|glycerolipid formation|glycerolipid biosynthesis													biological_process											owl:Class	
GO:0052740	biolink:NamedThing	1-acyl-2-lysophosphatidylserine acylhydrolase activity	Catalysis of the reaction: 1-acyl-2-lysophosphatidylserine + H2O = sn-glycerol-phosphoserine + a carboxylate.	tmpzr1t_l9r_go_relaxed.owl	phosphatidylserine-specific phospholipase A1 activity				EC:3.1.1.32									molecular_function											owl:Class	
GO:0003397	biolink:NamedThing	neuron migration involved in amphid sensory organ dendrite retrograde extension	The directed, self-propelled movement of a neuron that contributes to the process of retrograde extension of a dendrite of a neuron in the amphid sensory organ.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-12-09T09:52:18Z					biological_process											owl:Class	
GO:0003395	biolink:NamedThing	neuron migration involved in dendrite retrograde extension	The directed, self-propelled movement of a neuron that contributes to the process of retrograde extension of a dendrite.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-12-09T09:44:24Z					biological_process											owl:Class	
GO:1902710	biolink:NamedThing	GABA receptor complex	A protein complex which is capable of GABA receptor activity. Upon binding of gamma-aminobutyric acid (GABA) it transmits the signal from one side of the membrane to the other to initiate a change in cell activity. Major inhibitory receptor in vertebrate brain. Also found in other vertebrate tissues, invertebrates and possibly in plants. Effective benzodiazepine receptor.	tmpzr1t_l9r_go_relaxed.owl	gamma-aminobutyric acid receptor complex							bhm	2014-02-20T16:07:48Z					cellular_component											owl:Class	
GO:2000022	biolink:NamedThing	regulation of jasmonic acid mediated signaling pathway	Any process that modulates the frequency, rate or extent of jasmonic acid mediated signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	regulation of jasmonic acid mediated signalling pathway							tb	2010-08-05T11:24:11Z					biological_process											owl:Class	
GO:0002008	biolink:NamedThing	excitation of vasomotor center by chemoreceptor signaling	The process in which the molecular signal from the carotid and aortic bodies is relayed to the vasomotor center, causing it to signal an increase arterial pressure.	tmpzr1t_l9r_go_relaxed.owl	excitation of vasomotor center by chemoreceptor signalling													biological_process											owl:Class	
GO:0046934	biolink:NamedThing	phosphatidylinositol-4,5-bisphosphate 3-kinase activity	Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + ATP = a 1-phosphatidyl-1D-myo-inositol 3,4,5-trisphosphate + ADP + 2 H(+).	tmpzr1t_l9r_go_relaxed.owl	phosphatidylinositol 3-kinase, class I, catalyst activity|type I phosphoinositide 3-kinase activity|ATP:1-phosphatidyl-1D-myo-inositol-4,5-bisphosphate 3-phosphotransferase activity|phosphatidylinositol 3-kinase activity, class II|phosphatidylinositol 3-kinase activity, class I				Reactome:R-HSA-1250370|Reactome:R-HSA-5654709|Reactome:R-HSA-9672162|Reactome:R-HSA-5654701|Reactome:R-HSA-1306979|Reactome:R-HSA-186800|Reactome:R-HSA-9672177|Reactome:R-HSA-9603445|Reactome:R-HSA-5654705|Reactome:R-HSA-202365|Reactome:R-HSA-2029271|Reactome:R-HSA-392300|Reactome:R-HSA-5654692|Reactome:R-HSA-1839091|Reactome:R-HSA-1676048|Reactome:R-HSA-198266|Reactome:R-HSA-5654697|Reactome:R-HSA-5654714|Reactome:R-HSA-1226014|Reactome:R-HSA-9021627|Reactome:R-HSA-5655290|Reactome:R-HSA-5637801|Reactome:R-HSA-5655235|Reactome:R-HSA-5654717|Reactome:R-HSA-8852019|MetaCyc:2.7.1.153-RXN|Reactome:R-HSA-2424480|Reactome:R-HSA-437162|Reactome:R-HSA-9665407|Reactome:R-HSA-9664940|Reactome:R-HSA-389158|Reactome:R-HSA-2394007|Reactome:R-HSA-2316434|Reactome:R-HSA-5654690|Reactome:R-HSA-5218819|Reactome:R-HSA-1839107|Reactome:R-HSA-9664664|Reactome:R-HSA-2076220|Reactome:R-HSA-1306957|Reactome:R-HSA-177939|Reactome:R-HSA-5655323|Reactome:R-HSA-5655289|EC:2.7.1.153|KEGG_REACTION:R04545|Reactome:R-HSA-1250462|Reactome:R-HSA-8853323|RHEA:21292|Reactome:R-HSA-2730870									molecular_function											owl:Class	
GO:0120207	biolink:NamedThing	endocytosis, site selection	The process of selecting and or marking the position where endocytosis will occur.	tmpzr1t_l9r_go_relaxed.owl								krc	2019-05-15T21:25:49Z					biological_process											owl:Class	
GO:0016419	biolink:NamedThing	S-malonyltransferase activity	Catalysis of the transfer of a malonyl group to a sulfur atom on the acceptor molecule.	tmpzr1t_l9r_go_relaxed.owl					EC:2.3.1.39									molecular_function											owl:Class	
GO:0009668	biolink:NamedThing	plastid membrane organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of either of the lipid bilayers surrounding a plastid.	tmpzr1t_l9r_go_relaxed.owl	plastid membrane organisation|plastid membrane organization and biogenesis													biological_process											owl:Class	
GO:0008939	biolink:NamedThing	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity	Catalysis of the reaction: 5,6-dimethylbenzimidazole + nicotinate D-ribonucleotide = alpha-ribazole 5'-phosphate + H(+) + nicotinate.	tmpzr1t_l9r_go_relaxed.owl	CobT|N1-alpha-phosphoribosyltransferase activity|nicotinate mononucleotide (NaMN):5,6-dimethylbenzimidazole phosphoribosyltransferase activity|nicotinate ribonucleotide:benzimidazole (adenine) phosphoribosyltransferase activity|nicotinate-nucleotide:dimethylbenzimidazole phospho-D-ribosyltransferase activity|nicotinate mononucleotide-dimethylbenzimidazole phosphoribosyltransferase activity|nicotinate-nucleotide:5,6-dimethylbenzimidazole phospho-D-ribosyltransferase activity|N(1)-alpha-phosphoribosyltransferase activity				EC:2.4.2.21|KEGG_REACTION:R04148|RHEA:11196|MetaCyc:DMBPPRIBOSYLTRANS-RXN									molecular_function											owl:Class	
GO:0048304	biolink:NamedThing	positive regulation of isotype switching to IgG isotypes	Any process that activates or increases the frequency, rate or extent of isotype switching to IgG isotypes.	tmpzr1t_l9r_go_relaxed.owl	activation of isotype switching to IgG isotypes|positive regulation of isotype switch recombination to IgG isotypes|positive regulation of class switch recombination to IgG isotypes|up-regulation of isotype switching to IgG isotypes|up regulation of isotype switching to IgG isotypes|stimulation of isotype switching to IgG isotypes|positive regulation of class switching to IgG isotypes|upregulation of isotype switching to IgG isotypes													biological_process											owl:Class	
GO:2001032	biolink:NamedThing	regulation of double-strand break repair via nonhomologous end joining	Any process that modulates the frequency, rate or extent of double-strand break repair via nonhomologous end joining.	tmpzr1t_l9r_go_relaxed.owl	regulation of NHEJ							yaf	2011-08-24T09:25:39Z					biological_process											owl:Class	
GO:1904826	biolink:NamedThing	regulation of hydrogen sulfide biosynthetic process	Any process that modulates the frequency, rate or extent of hydrogen sulfide biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of hydrogen sulphide biosynthetic process|regulation of hydrogen sulfide anabolism|regulation of hydrogen sulfide formation|regulation of hydrogen sulfide synthesis|regulation of hydrogen sulfide biosynthesis|regulation of hydrogen sulphide biosynthesis							rph	2015-11-24T10:15:26Z					biological_process											owl:Class	
GO:0072249	biolink:NamedThing	metanephric glomerular visceral epithelial cell development	The process whose specific outcome is the progression of a metanephric glomerular visceral epithelial cell over time, from its formation to the mature structure. A metanephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the metanephros.	tmpzr1t_l9r_go_relaxed.owl	metanephric podocyte development							mah	2010-03-19T03:46:26Z					biological_process											owl:Class	
GO:0005992	biolink:NamedThing	trehalose biosynthetic process	The chemical reactions and pathways resulting in the formation of trehalose, a disaccharide isomeric with sucrose and obtained from certain lichens and fungi.	tmpzr1t_l9r_go_relaxed.owl	mykose biosynthetic process|mykose biosynthesis|trehalose biosynthesis|trehalose synthesis|mycose biosynthetic process|trehalose anabolism|trehalose formation|mycose biosynthesis				MetaCyc:TREHALOSESYN-PWY|MetaCyc:PWY-881|MetaCyc:TRESYN-PWY									biological_process											owl:Class	
GO:2001225	biolink:NamedThing	regulation of chloride transport	Any process that modulates the frequency, rate or extent of chloride transport.	tmpzr1t_l9r_go_relaxed.owl								dph	2011-11-18T05:45:56Z					biological_process											owl:Class	
GO:0150103	biolink:NamedThing	reactive gliosis	A neuroinflammatory response, occurring over several days, during which glial cells undergo nonspecific reactive changes in response to damage to the central nervous system (CNS); typically involves the proliferation or hypertrophy of different types of glial cells.	tmpzr1t_l9r_go_relaxed.owl	gliosis							bc	2019-05-21T12:37:31Z					biological_process											owl:Class	
GO:0045136	biolink:NamedThing	development of secondary sexual characteristics	The process whose specific outcome is the progression of the secondary sexual characteristics over time, from their formation to the mature structures. In humans, these include growth of axillary, chest, and pubic hair, voice changes, testicular/penile enlargement, breast development and menstrual periods. Development occurs in response to sex hormone secretion.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0048252	biolink:NamedThing	lauric acid metabolic process	The chemical reactions and pathways involving lauric acid, a fatty acid with the formula CH3(CH2)10COOH. Derived from vegetable sources.	tmpzr1t_l9r_go_relaxed.owl	n-dodecanoic acid metabolism|lauric acid metabolism|n-dodecanoic acid metabolic process													biological_process											owl:Class	
GO:0040032	biolink:NamedThing	post-embryonic body morphogenesis	The process in which the anatomical structures of the post-embryonic soma are generated and organized.	tmpzr1t_l9r_go_relaxed.owl						Note that this term was 'body morphogenesis (sensu Nematoda)'.								biological_process											owl:Class	
GO:0010171	biolink:NamedThing	body morphogenesis	The process in which the anatomical structures of the soma are generated and organized.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0032766	biolink:NamedThing	NHE3/E3KARP/ACTN4 complex	A heterotrimeric protein complex formed by the association of NHE3, E3KARP and alpha-actinin upon an increase in calcium ion concentration; found in clusters localized on plasma membrane and in intracellular compartments.	tmpzr1t_l9r_go_relaxed.owl	NHE3/E3KARP/alpha-actinin complex													cellular_component											owl:Class	
GO:0009672	biolink:NamedThing	auxin:proton symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: auxin(out) + H+(out) = auxin(in) + H+(in).	tmpzr1t_l9r_go_relaxed.owl	auxin:hydrogen symporter activity													molecular_function											owl:Class	
GO:0080161	biolink:NamedThing	auxin transmembrane transporter activity	Enables the transfer of auxins from one side of a membrane to the other. Auxins are plant hormones that regulate aspects of plant growth.	tmpzr1t_l9r_go_relaxed.owl								dhl	2010-09-23T03:37:43Z					molecular_function											owl:Class	
GO:0106388	biolink:NamedThing	18S rRNA aminocarboxypropyltransferase activity	Catalysis of the reaction: N1-methylpseudouridine in 18S rRNA + S-adenosyl-L-methionine = H+ + N1-methyl-N3-[(3S)-3-amino-3-carboxypropyl]pseudouridine in 18S rRNA + S-methyl-5'-thioadenosine.	tmpzr1t_l9r_go_relaxed.owl					RHEA:63296			hjd	2021-07-13T14:01:28Z					molecular_function											owl:Class	
GO:2000426	biolink:NamedThing	negative regulation of apoptotic cell clearance	Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic cell clearance.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of efferocytosis|negative regulation of programmed cell clearance|negative regulation of apoptotic cell removal							bf	2011-02-25T11:50:39Z					biological_process											owl:Class	
GO:2000425	biolink:NamedThing	regulation of apoptotic cell clearance	Any process that modulates the frequency, rate or extent of apoptotic cell clearance.	tmpzr1t_l9r_go_relaxed.owl	regulation of programmed cell clearance|regulation of efferocytosis|regulation of apoptotic cell removal							bf	2011-02-25T11:50:11Z					biological_process											owl:Class	
GO:0072717	biolink:NamedThing	cellular response to actinomycin D	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an actinomycin D stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2012-04-26T02:06:55Z					biological_process											owl:Class	
GO:0043940	biolink:NamedThing	regulation of sexual sporulation resulting in formation of a cellular spore	Any process that modulates the frequency, rate or extent of the formation of cellular spores derived from the products of meiosis.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0106214	biolink:NamedThing	regulation of vesicle fusion with Golgi apparatus	Any process that modulates the frequency, rate or extent of vesicle fusion with Golgi apparatus.	tmpzr1t_l9r_go_relaxed.owl								hjd	2019-06-27T15:12:22Z					biological_process											owl:Class	
GO:0070328	biolink:NamedThing	triglyceride homeostasis	Any process involved in the maintenance of an internal steady state of triglyceride within an organism or cell.	tmpzr1t_l9r_go_relaxed.owl	triacylglycerol homeostasis													biological_process											owl:Class	
GO:0055090	biolink:NamedThing	acylglycerol homeostasis	Any process involved in the maintenance of an internal steady state of acylglycerol within an organism or cell.	tmpzr1t_l9r_go_relaxed.owl	glyceride homeostasis													biological_process											owl:Class	
GO:0004518	biolink:NamedThing	nuclease activity	Catalysis of the hydrolysis of ester linkages within nucleic acids.	tmpzr1t_l9r_go_relaxed.owl						Note that 'tRNA nucleotidyltransferase activity ; GO:0009022', also known as 'ribonuclease PH', and 'DNA-(apurinic or apyrimidinic site) lyase activity ; GO:0003906' do not have parentage in the 'nuclease activity' branch of the ontology because both GO and the Enzyme Commission define nuclease activity as a type of hydrolysis.								molecular_function											owl:Class	
GO:0005639	biolink:NamedThing	integral component of nuclear inner membrane	The component of the nuclear inner membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.	tmpzr1t_l9r_go_relaxed.owl	integral to nuclear inner membrane													cellular_component											owl:Class	
GO:0015169	biolink:NamedThing	glycerol-3-phosphate transmembrane transporter activity	Enables the transfer of glycerol-3-phosphate from one side of a membrane to the other. Glycerol-3-phosphate is a phosphoric monoester of glycerol.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0009669	biolink:NamedThing	sucrose:cation symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sucrose(out) + monovalent cation(out) = sucrose(in) + monovalent cation(in).	tmpzr1t_l9r_go_relaxed.owl	sucrose:monovalent cation symporter activity|sucrose permease activity													molecular_function											owl:Class	
GO:0106318	biolink:NamedThing	methane monooxygenase NADPH activity	Catalysis of the reaction: methane + NADPH + H+ + O2 = methanol + NADP+ + H2O.	tmpzr1t_l9r_go_relaxed.owl					EC:1.14.13.25|RHEA:13641			hjd	2020-09-23T15:12:49Z					molecular_function											owl:Class	
GO:1901088	biolink:NamedThing	benzylpenicillin biosynthetic process	The chemical reactions and pathways resulting in the formation of benzylpenicillin.	tmpzr1t_l9r_go_relaxed.owl	penicillin G biosynthesis|penicillin G formation|benzylpenicillin anabolism|benzylpenicillin synthesis|benzylpenicillin biosynthesis|penicillin G anabolism|penicillin G synthesis|benzylpenicillin formation							yaf	2012-07-05T10:29:07Z					biological_process											owl:Class	
GO:1901086	biolink:NamedThing	benzylpenicillin metabolic process	The chemical reactions and pathways involving benzylpenicillin.	tmpzr1t_l9r_go_relaxed.owl	penicillin G metabolism|benzylpenicillin metabolism							yaf	2012-07-05T10:28:33Z					biological_process											owl:Class	
GO:1900580	biolink:NamedThing	(17Z)-protosta-17(20),24-dien-3beta-ol catabolic process	The chemical reactions and pathways resulting in the breakdown of (17Z)-protosta-17(20),24-dien-3beta-ol.	tmpzr1t_l9r_go_relaxed.owl	(17Z)-protosta-17(20),24-dien-3beta-ol breakdown|(17Z)-protosta-17(20),24-dien-3beta-ol catabolism|(17Z)-protosta-17(20),24-dien-3beta-ol degradation							di	2012-05-15T06:47:30Z					biological_process											owl:Class	
GO:1900579	biolink:NamedThing	(17Z)-protosta-17(20),24-dien-3beta-ol metabolic process	The chemical reactions and pathways involving (17Z)-protosta-17(20),24-dien-3beta-ol.	tmpzr1t_l9r_go_relaxed.owl	(17Z)-protosta-17(20),24-dien-3beta-ol metabolism							di	2012-05-15T06:47:07Z					biological_process											owl:Class	
GO:0048829	biolink:NamedThing	root cap development	The process whose specific outcome is the progression of the root cap over time, from its formation to the mature structure. The root cap protects the root meristem from friction as the root grows through the soil. The cap is made up of a group of parenchyma cells which secrete a glycoprotein mucilage as a lubricant.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0002844	biolink:NamedThing	negative regulation of tolerance induction to tumor cell	Any process that stops, prevents, or reduces the frequency, rate, or extent of tolerance induction to tumor cell.	tmpzr1t_l9r_go_relaxed.owl	downregulation of tolerance induction to tumor cell|negative regulation of tolerance induction to tumour cell|inhibition of tolerance induction to tumor cell|down regulation of tolerance induction to tumor cell|down-regulation of tolerance induction to tumor cell													biological_process											owl:Class	
GO:0060015	biolink:NamedThing	granulosa cell fate commitment	The cell fate commitment of precursor cells that will become granulosa cells.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0044597	biolink:NamedThing	daunorubicin metabolic process	The chemical reactions and pathways involving daunorubicin, a chemotherapeutic of the anthracycline family that is given as a treatment for some types of cancer.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-05-01T03:09:51Z					biological_process											owl:Class	
GO:0102571	biolink:NamedThing	[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase activity	Catalysis of the reaction: H2O + an N-acetyl-alpha-D-glucosaminyl-[glycoprotein] <=> N-acetyl-alpha-D-glucosaminide + a [glycoprotein]-(L-serine/L-threonine).	tmpzr1t_l9r_go_relaxed.owl					EC:3.2.1.169|MetaCyc:RXN-15215									molecular_function											owl:Class	
GO:0102006	biolink:NamedThing	4-methyl-2-oxopentanoate dehydrogenase activity	Catalysis of the reaction: 4-methyl-2-oxopentanoate + coenzyme A(4-) + NAD(1-) <=> isovaleryl-CoA(4-) + carbon dioxide + NADH(2-).	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:2KETO-4METHYL-PENTANOATE-DEHYDROG-RXN|RHEA:25177									molecular_function											owl:Class	
GO:0036117	biolink:NamedThing	hyaluranon cable	A cable structure, surrounding some cell types (e.g. proximal or bronchial tubular epithelial cells), and composed of hyaluranon (HA), a ubiquitous connective tissue glycosaminoglycan.	tmpzr1t_l9r_go_relaxed.owl	HA cable							bf	2012-02-16T10:53:37Z					cellular_component											owl:Class	
GO:0061234	biolink:NamedThing	mesonephric glomerulus morphogenesis	The process in which the anatomical structures of the mesonephric glomerulus are generated and organized. The mesonephric glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate mesonephros.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-08-19T02:53:35Z					biological_process											owl:Class	
GO:0006782	biolink:NamedThing	protoporphyrinogen IX biosynthetic process	The chemical reactions and pathways resulting in the formation of protoporphyrinogen IX.	tmpzr1t_l9r_go_relaxed.owl	protoporphyrinogen IX formation|protoporphyrinogen IX biosynthesis|protoporphyrinogen IX anabolism|protoporphyrinogen IX synthesis													biological_process											owl:Class	
GO:0042852	biolink:NamedThing	L-alanine biosynthetic process	The chemical reactions and pathways resulting in the formation of L-alanine, the L-enantiomer of 2-aminopropanoic acid, i.e. (2S)-2-aminopropanoic acid.	tmpzr1t_l9r_go_relaxed.owl	L-alanine biosynthesis|L-alanine anabolism|L-alanine formation|L-alanine synthesis													biological_process											owl:Class	
GO:0032330	biolink:NamedThing	regulation of chondrocyte differentiation	Any process that modulates the frequency, rate or extent of chondrocyte differentiation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0044228	biolink:NamedThing	host cell surface	The external part of the host cell wall and/or host plasma membrane.	tmpzr1t_l9r_go_relaxed.owl								jl	2009-12-03T01:49:45Z					cellular_component											owl:Class	
GO:0051691	biolink:NamedThing	cellular oligosaccharide metabolic process	The chemical reactions and pathways involving oligosaccharides, molecules with between two and (about) 20 monosaccharide residues connected by glycosidic linkages, as carried out by individual cells.	tmpzr1t_l9r_go_relaxed.owl	cellular oligosaccharide metabolism													biological_process											owl:Class	
GO:0030408	biolink:NamedThing	glycine formimidoyltransferase activity	Catalysis of the reaction: 5-formimidoyltetrahydrofolate + glycine = (6S)-5,6,7,8-tetrahydrofolate + N-formimidoylglycine.	tmpzr1t_l9r_go_relaxed.owl	formiminotransferase activity|formiminoglycine formiminotransferase activity|glycine formiminotransferase activity|FIG formiminotransferase activity|formimidoyltransferase activity|5-formimidoyltetrahydrofolate:glycine N-formimidoyltransferase activity				RHEA:24288|KEGG_REACTION:R02729|EC:2.1.2.4|MetaCyc:GLYCINE-FORMIMINOTRANSFERASE-RXN									molecular_function											owl:Class	
GO:0071352	biolink:NamedThing	cellular response to interleukin-2	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-2 stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to IL-2							mah	2009-12-11T02:50:48Z					biological_process											owl:Class	
GO:0051328	biolink:NamedThing	meiotic interphase	The cell cycle phase which begins after cytokinesis and ends when meiotic prophase begins. Meiotic cells have an interphase after each meiotic division, but only interphase I involves replication of the cell's DNA.	tmpzr1t_l9r_go_relaxed.owl	interphase of meiotic cell cycle					Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).								biological_process											owl:Class	
GO:0051897	biolink:NamedThing	positive regulation of protein kinase B signaling	Any process that activates or increases the frequency, rate or extent of protein kinase B signaling, a series of reactions mediated by the intracellular serine/threonine kinase protein kinase B.	tmpzr1t_l9r_go_relaxed.owl	upregulation of protein kinase B signaling cascade|up-regulation of protein kinase B signaling cascade|stimulation of protein kinase B signaling cascade|positive regulation of AKT signaling cascade|activation of protein kinase B signaling cascade|positive regulation of PKB signaling cascade|up regulation of protein kinase B signaling cascade|positive regulation of AKT signalling cascade|positive regulation of protein kinase B signaling cascade|positive regulation of PKB signalling cascade|positive regulation of protein kinase B signalling cascade													biological_process											owl:Class	
GO:0004864	biolink:NamedThing	protein phosphatase inhibitor activity	Binds to and stops, prevents or reduces the activity of a protein phosphatase, an enzyme that hydrolyzes phosphate groups from phosphorylated proteins.	tmpzr1t_l9r_go_relaxed.owl	protein phosphatase 2 inhibitor activity|phosphoprotein phosphatase inhibitor activity|protein phosphatase type 2A inhibitor activity							rb	2015-03-03T23:57:25Z			GO:1990681		molecular_function											owl:Class	
GO:0044325	biolink:NamedThing	transmembrane transporter binding	Binding to a transmembrane transporter, a protein or protein complex that enables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	ion channel binding	https://github.com/geneontology/go-ontology/issues/21331						jl	2010-08-04T12:52:59Z					molecular_function											owl:Class	
GO:0004455	biolink:NamedThing	ketol-acid reductoisomerase activity	Catalysis of the reaction: (R)-2,3-dihydroxy-3-methylbutanoate + NADP+ = (S)-2-hydroxy-2-methyl-3-oxobutanoate + NADPH + H+.	tmpzr1t_l9r_go_relaxed.owl	reductoisomerase activity|dihydroxyisovalerate (isomerizing) dehydrogenase activity|alpha-keto-beta-hydroxylacyl reductoisomerase activity|isomeroreductase activity|acetolactate reductoisomerase activity|ketol acid reductoisomerase activity|(R)-2,3-dihydroxy-3-methylbutanoate:NADP+ oxidoreductase (isomerizing)|2-hydroxy-3-keto acid reductoisomerase activity|acetohydroxy acid reductoisomerase activity|dihydroxyisovalerate dehydrogenase (isomerizing) activity|acetohydroxy acid isomeroreductase activity				MetaCyc:ACETOLACTREDUCTOISOM-RXN|RHEA:22068|EC:1.1.1.86									molecular_function											owl:Class	
GO:0015620	biolink:NamedThing	ferric-enterobactin transmembrane transporter activity	Enables the transfer of ferric-enterobactin from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1902426	biolink:NamedThing	deactivation of mitotic spindle assembly checkpoint	A positive regulation of the mitotic metaphase/anaphase transition that results from deactivation of the mitotic spindle assembly checkpoint.	tmpzr1t_l9r_go_relaxed.owl	down regulation of Mad2-dependent checkpoint|downregulation of Mad2-dependent checkpoint|mitotic spindle assembly deactivation|inhibition of mitotic spindle assembly checkpoint|down-regulation of mitotic spindle assembly checkpoint|inhibition of mitotic cell cycle spindle assembly checkpoint|down-regulation of mitotic cell cycle spindle assembly checkpoint|negative regulation of mitotic spindle assembly checkpoint|down regulation of mitotic cell cycle spindle assembly checkpoint|downregulation of mitotic spindle assembly checkpoint|down regulation of mitotic spindle assembly checkpoint|negative regulation of mitotic cell cycle spindle assembly checkpoint|mitotic spindle assembly checkpoint silencing|inhibition of Mad2-dependent checkpoint|negative regulation of Mad2-dependent checkpoint|downregulation of mitotic cell cycle spindle assembly checkpoint|down-regulation of Mad2-dependent checkpoint					A mitotic spindle assembly checkpoint is either activated or switched off; no other means of reducing the frequency, rate or extent of this process are currently known.		dph	2013-09-20T18:42:07Z					biological_process											owl:Class	
GO:0006636	biolink:NamedThing	unsaturated fatty acid biosynthetic process	The chemical reactions and pathways resulting in the formation of an unsaturated fatty acid, any fatty acid containing one or more double bonds between carbon atoms.	tmpzr1t_l9r_go_relaxed.owl	polyunsaturated fatty acid biosynthesis|unsaturated fatty acid synthesis|unsaturated fatty acid anabolism|unsaturated fatty acid biosynthesis|unsaturated fatty acid formation|fatty acid desaturation				MetaCyc:PWY-782|MetaCyc:PWY-762									biological_process											owl:Class	
GO:0018142	biolink:NamedThing	protein-DNA covalent cross-linking	The formation of a covalent cross-link between DNA and a protein.	tmpzr1t_l9r_go_relaxed.owl	DNA-protein covalent cross-linking													biological_process											owl:Class	
GO:0018143	biolink:NamedThing	nucleic acid-protein covalent cross-linking	The formation of a covalent cross-link between a nucleic acid and a protein.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0075269	biolink:NamedThing	positive regulation of aecium development	Any process that activates, maintains or increases the frequency, rate or extent of aecium development, a process in which a cuplike structure containing chains of aeciospores is formed.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0102727	biolink:NamedThing	3beta-hydroxysteroid dehydrogenase activity	Catalysis of the reaction: campest-4-en-3beta-ol + NAD = campest-4-en-3-one + NADH + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-710									molecular_function											owl:Class	
GO:0044072	biolink:NamedThing	negative regulation by symbiont of host cell cycle	The process in which a symbiont organism stops, prevents or reduces the rate or extent of its host's progression through its cell cycle via direct interactions with the host cell macromolecular machinery.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0021825	biolink:NamedThing	substrate-dependent cerebral cortex tangential migration	The process where neuronal precursors migrate tangentially in the cerebral cortex, primarily guided through physical cell-cell interactions.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0021800	biolink:NamedThing	cerebral cortex tangential migration	The migration of cells in the cerebral cortex in which cells move orthogonally to the direction of radial migration and do not use radial glial cell processes as substrates for migration.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0000323	biolink:NamedThing	lytic vacuole	A vacuole that is maintained at an acidic pH and which contains degradative enzymes, including a wide variety of acid hydrolases.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0016208	biolink:NamedThing	AMP binding	Binding to AMP, adenosine monophosphate.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0071681	biolink:NamedThing	cellular response to indole-3-methanol	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an indole-3-methanol stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to indole-3-carbinol							mah	2010-02-18T04:05:29Z					biological_process											owl:Class	
GO:0060086	biolink:NamedThing	circadian temperature homeostasis	Any homeostatic process in which an organism modulates its internal body temperature at different values with a regularity of approximately 24 hours.	tmpzr1t_l9r_go_relaxed.owl	circadian regulation of body temperature|circadian thermoregulation													biological_process											owl:Class	
GO:1990319	biolink:NamedThing	collagen type XX trimer	A collagen homotrimer of alpha1(XX) chains.	tmpzr1t_l9r_go_relaxed.owl								bhm	2014-03-14T16:31:21Z					cellular_component											owl:Class	
GO:0047865	biolink:NamedThing	dimethylglycine dehydrogenase activity	Catalysis of the reaction: N,N-dimethylglycine + electron-transfer flavoprotein + H2O = sarcosine + formaldehyde + reduced electron-transfer flavoprotein.	tmpzr1t_l9r_go_relaxed.owl	N,N-dimethylglycine:acceptor oxidoreductase (demethylating)|N,N-dimethylglycine:(acceptor) oxidoreductase (demethylating)|N,N-dimethylglycine oxidase activity				EC:1.5.8.4|Reactome:R-HSA-6797653|RHEA:52856|MetaCyc:DIMETHYLGLYCINE-DEHYDROGENASE-RXN|KEGG_REACTION:R01565	Note that this was EC:1.5.99.2.								molecular_function											owl:Class	
GO:0035864	biolink:NamedThing	response to potassium ion	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a potassium ion stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to K+ ion|response to potassium							bf	2011-05-25T02:58:45Z					biological_process											owl:Class	
GO:1901821	biolink:NamedThing	alpha-zeacarotene biosynthetic process	The chemical reactions and pathways resulting in the formation of alpha-zeacarotene.	tmpzr1t_l9r_go_relaxed.owl	alpha-zeacarotene synthesis|alpha-zeacarotene biosynthesis|alpha-zeacarotene formation|alpha-zeacarotene anabolism							yaf	2013-01-22T10:51:14Z					biological_process											owl:Class	
GO:0036468	biolink:NamedThing	L-dopa decarboxylase activity	Catalysis of the reaction: L-dopa + H+ = CO2 + dopamine.	tmpzr1t_l9r_go_relaxed.owl	4-dihydroxyl-L-phenylalanine decarboxylase activity|DDC activity|DOPA decarboxylase activity				RHEA:12272			bf	2014-07-21T09:22:24Z					molecular_function											owl:Class	
GO:0004058	biolink:NamedThing	aromatic-L-amino-acid decarboxylase activity	Catalysis of the reaction: L-amino acid + H+ = R-H + CO2.	tmpzr1t_l9r_go_relaxed.owl	DOPA decarboxylase activity|aromatic-L-amino-acid carboxy-lyase activity|aromatic-L-amino-acid carboxy-lyase (tryptamine-forming)|5-hydroxytryptophan decarboxylase activity|tryptophan decarboxylase activity|hydroxytryptophan decarboxylase activity|aromatic amino acid decarboxylase activity|L-DOPA decarboxylase activity				Reactome:R-HSA-209924|Reactome:R-HSA-209859|EC:4.1.1.28|MetaCyc:AROMATIC-L-AMINO-ACID-DECARBOXYLASE-RXN							GO:0016400		molecular_function											owl:Class	
GO:0043542	biolink:NamedThing	endothelial cell migration	The orderly movement of an endothelial cell into the extracellular matrix to form an endothelium.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0120243	biolink:NamedThing	2-iminopropanoate deaminase activity	Catalysis of the reaction: 2-iminopropanoate + H2O = NH4(+) + pyruvate.	tmpzr1t_l9r_go_relaxed.owl	2-iminobutanoate/2-iminopropanoate deaminase	https://github.com/geneontology/go-ontology/issues/19832			MetaCyc:RXN-15127|RHEA:40671|KEGG_REACTION:R11099			krc	2020-07-29T19:41:18Z					molecular_function											owl:Class	
GO:0120241	biolink:NamedThing	2-iminobutanoate/2-iminopropanoate deaminase	Catalyzes the hydrolytic deamination of imine intermediates formed by several types of pyridoxal-5'-phosphate-dependent dehydratases, such as EC 4.3.1.19 and EC 4.3.1.17.	tmpzr1t_l9r_go_relaxed.owl	2-iminopropanoate deaminase|2-iminobutanoate deaminase|imine intermediate deaminase activity|enamine/imine deaminase	https://github.com/geneontology/go-ontology/issues/19832			EC:3.5.99.10	This enzyme, which has been found in all species and tissues examined, catalyzes the hydrolytic deamination of imine intermediates formed by several types of pyridoxal-5'-phosphate-dependent dehydratases, such as EC 4.3.1.19 and EC 4.3.1.17. The reactions, which can occur spontaneously, are accelerated to minimize the cellular damage that could be caused by these reactive intermediates (from EC:3.5.99.10).		krc	2020-07-29T17:28:19Z					molecular_function											owl:Class	
GO:1990943	biolink:NamedThing	mating type region replication fork barrier binding	Binding to the replication fork barrier found in the mating type region of fission yeast.	tmpzr1t_l9r_go_relaxed.owl	RTS1 barrier binding|RTS1 element binding							mah	2016-04-06T16:08:43Z					molecular_function											owl:Class	
GO:0097004	biolink:NamedThing	adipokinetic hormone binding	Binding to an adipokinetic hormone. Adipokinetic hormones (AKHs) are peptide hormones that are involved in the mobilization of sugar and lipids from the insect fat body during energy-requiring activities such as flight and locomotion. They also contribute to hemolymph sugar homeostasis.	tmpzr1t_l9r_go_relaxed.owl	AKH binding							pr	2011-03-14T12:50:02Z					molecular_function											owl:Class	
GO:0070440	biolink:NamedThing	Mad-Max-mSin3B complex	A transcriptional repressor complex that contains a heterodimer of the bHLH-ZIP proteins Mad and Max, plus mSin3B, a homolog of the yeast Sin3p.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0035861	biolink:NamedThing	site of double-strand break	A region of a chromosome at which a DNA double-strand break has occurred. DNA damage signaling and repair proteins accumulate at the lesion to respond to the damage and repair the DNA to form a continuous DNA helix.	tmpzr1t_l9r_go_relaxed.owl	site of DSB|DNA damage focus|ionizing radiation-induced foci|IRIF|DNA damage foci							bf	2011-05-17T03:04:42Z					cellular_component											owl:Class	
GO:0090734	biolink:NamedThing	site of DNA damage	A region of a chromosome at which DNA damage has occurred. DNA damage signaling and repair proteins accumulate at the lesion to respond to the damage and repair the DNA to form a continuous DNA helix.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:DNA_repair			tb	2017-02-03T17:24:08Z					cellular_component											owl:Class	
GO:0019341	biolink:NamedThing	dibenzo-p-dioxin catabolic process	The chemical reactions and pathways resulting in the breakdown of dibenzo-p-dioxin, a substance composed of two benzene rings linked by two ether bonds.	tmpzr1t_l9r_go_relaxed.owl	dibenzo-p-dioxin degradation|dibenzo-p-dioxin breakdown|dibenzo-p-dioxin catabolism				MetaCyc:P661-PWY									biological_process											owl:Class	
GO:1900366	biolink:NamedThing	negative regulation of defense response to insect	Any process that stops, prevents or reduces the frequency, rate or extent of defense response to insect.	tmpzr1t_l9r_go_relaxed.owl	down regulation of physiological defense response to insect|inhibition of defense response to insect|negative regulation of physiological defense response to insect|down regulation of defense response to insect|downregulation of physiological defense response to insect|down-regulation of physiological defense response to insect|downregulation of defense response to insect|susceptibility to insect|down-regulation of defense response to insect|inhibition of physiological defense response to insect							dhl	2012-04-12T04:44:00Z					biological_process											owl:Class	
GO:1903768	biolink:NamedThing	taste receptor complex	A protein complex which is capable of taste receptor activity.	tmpzr1t_l9r_go_relaxed.owl								rl	2014-12-22T16:53:45Z					cellular_component											owl:Class	
GO:0031056	biolink:NamedThing	regulation of histone modification	Any process that modulates the frequency, rate or extent of the covalent alteration of a histone.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0098752	biolink:NamedThing	integral component of the cytoplasmic side of the plasma membrane	The component of the plasma membrane consisting of the gene products that penetrate only the cytoplasmic side of the membrane.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0019238	biolink:NamedThing	cyclohydrolase activity	Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a cyclic amidine, a compound of the form R-C(=NH)-NH2, in a reaction that involves the opening of a ring.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0060742	biolink:NamedThing	epithelial cell differentiation involved in prostate gland development	The process in which a relatively unspecialized cell acquires specialized features of an epithelial cell of the prostate gland.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-06-16T09:32:34Z					biological_process											owl:Class	
GO:0043699	biolink:NamedThing	leucosome	A tissue-specific, membrane-bounded cytoplasmic organelle within which uric acid and/or purines crystalize in reflective stacks. Leucosomes are synthesized in leucophore cells and have a whitish cast.	tmpzr1t_l9r_go_relaxed.owl	refractosome													cellular_component											owl:Class	
GO:0048770	biolink:NamedThing	pigment granule	A small, subcellular membrane-bounded vesicle containing pigment and/or pigment precursor molecules. Pigment granule biogenesis is poorly understood, as pigment granules are derived from multiple sources including the endoplasmic reticulum, coated vesicles, lysosomes, and endosomes.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0039688	biolink:NamedThing	viral double stranded DNA replication via reverse transcription	A DNA replication process that uses viral RNA as a template for RNA-dependent DNA polymerases (e.g. reverse transcriptase) that synthesize the new strands.	tmpzr1t_l9r_go_relaxed.owl	RNA-dependent viral DNA replication|viral RNA-dependent DNA replication|dsDNA replication via RNA intermediate				VZ:1938			bf	2013-10-17T15:00:08Z					biological_process											owl:Class	
GO:0039693	biolink:NamedThing	viral DNA genome replication	The replication of a viral DNA genome.	tmpzr1t_l9r_go_relaxed.owl	viral DNA replication|viral DNA-dependent DNA replication|DNA-dependent viral DNA replication							bf	2013-10-23T15:22:31Z			GO:0039681		biological_process											owl:Class	
GO:0099061	biolink:NamedThing	integral component of postsynaptic density membrane	The component of the postsynaptic density membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0099060	biolink:NamedThing	integral component of postsynaptic specialization membrane	The component of the postsynaptic specialization membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0018601	biolink:NamedThing	4-nitrophenol 2-monooxygenase activity	Catalysis of the reaction: 4-nitrophenol + H(+) + NADH + O(2) = 4-nitrocatechol + H(2)O + NAD(+).	tmpzr1t_l9r_go_relaxed.owl	4-nitrophenol hydroxylase activity|4-nitrophenol,NADH:oxygen oxidoreductase (2-hydroxylating)|4-nitrophenol-2-hydroxylase activity				UM-BBD_reactionID:r0230|KEGG_REACTION:R03023|MetaCyc:4-NITROPHENOL-2-MONOOXYGENASE-RXN|EC:1.14.13.29|RHEA:12568									molecular_function											owl:Class	
GO:0070053	biolink:NamedThing	thrombospondin receptor activity	Combining with thrombospondin and transmitting the signal to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0047594	biolink:NamedThing	6-beta-hydroxyhyoscyamine epoxidase activity	Catalysis of the reaction: (6S)-6-hydroxyhyoscyamine + 2-oxoglutarate + O(2) = CO(2) + H(2)O + H(+) + scopolamine + succinate.	tmpzr1t_l9r_go_relaxed.owl	(6S)-6-hydroxyhyoscyamine,2-oxoglutarate oxidoreductase (epoxide-forming)|6beta-hydroxyhyoscyamine epoxidase activity|hydroxyhyoscyamine dioxygenase activity				KEGG_REACTION:R03737|RHEA:12797|EC:1.14.20.13|MetaCyc:6-BETA-HYDROXYHYOSCYAMINE-EPOXIDASE-RXN									molecular_function											owl:Class	
GO:0072696	biolink:NamedThing	positive regulation of DNA recombination at telomere	Any process that activates or increases the frequency, rate or extent of DNA recombination within the telomere.	tmpzr1t_l9r_go_relaxed.owl	activation of telomeric recombination at telomere|up regulation of telomeric recombination at telomere|up-regulation of telomeric recombination at telomere|upregulation of telomeric recombination at telomere|positive regulation of telomeric recombination							mah	2012-04-03T11:28:19Z					biological_process											owl:Class	
GO:0014737	biolink:NamedThing	positive regulation of muscle atrophy	Any process that activates or increases the frequency, rate or extent of muscle atrophy.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0014735	biolink:NamedThing	regulation of muscle atrophy	Any process that modulates the frequency, rate or extent of muscle atrophy.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0051154	biolink:NamedThing	negative regulation of striated muscle cell differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of striated muscle cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of striated muscle cell differentiation|downregulation of striated muscle cell differentiation|down regulation of striated muscle cell differentiation|inhibition of striated muscle cell differentiation													biological_process											owl:Class	
GO:0120260	biolink:NamedThing	ciliary microtubule quartet	A set of four specialized microtubules that originates from the basal bodies and wraps around the ciliary pocket membrane, likely supporting its distinct flask shape.	tmpzr1t_l9r_go_relaxed.owl	ciliary MtQ	https://github.com/geneontology/go-ontology/issues/20035				Note that cilia and eukaryotic flagella are deemed to be equivalent. In diplomonad species, such as Giardia, the axoneme may extend intracellularly up to 5um away from the plane of the plasma membrane.		krc	2020-09-29T16:22:22Z					cellular_component											owl:Class	
GO:0004608	biolink:NamedThing	phosphatidylethanolamine N-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + phosphatidylethanolamine = S-adenosyl-L-homocysteine + H(+) + phosphatidyl-N-methylethanolamine.	tmpzr1t_l9r_go_relaxed.owl	phosphatidylethanolamine methyltransferase activity|lipid methyl transferase activity|PEMT|S-adenosyl-L-methionine:phosphatidylethanolamine N-methyltransferase activity|phosphatidylethanolamine-N-methylase activity|LMTase activity|phosphatidylethanolamine-S-adenosylmethionine methyltransferase activity				RHEA:11164|KEGG_REACTION:R02056|MetaCyc:2.1.1.17-RXN|Reactome:R-HSA-1483174|EC:2.1.1.17									molecular_function											owl:Class	
GO:0120273	biolink:NamedThing	ciliary centrin arm assembly	The aggregation, arrangement and bonding together of a set of macromolecules to form a ciliary centrin arm, a rod-shaped protein complex containing Centrin4 protein that flanks the flagellum attachment zone (FAZ) filament and the quartet microtubules.	tmpzr1t_l9r_go_relaxed.owl	ciliary centrin arm formation	https://github.com/geneontology/go-ontology/issues/20088						krc	2020-10-08T23:01:46Z					biological_process											owl:Class	
GO:1904081	biolink:NamedThing	positive regulation of transcription from RNA polymerase II promoter involved in neuron differentiation	Any positive regulation of transcription from RNA polymerase II promoter that is involved in neuron differentiation.	tmpzr1t_l9r_go_relaxed.owl	upregulation of global transcription from RNA polymerase II promoter involved in neuron differentiation|positive regulation of transcription from RNA polymerase II promoter, global involved in neuron differentiation|positive regulation of transcription from Pol II promoter involved in neuron differentiation|positive regulation of gene-specific transcription from RNA polymerase II promoter involved in neuron differentiation|activation of global transcription from RNA polymerase II promoter involved in neuron differentiation|up regulation of transcription from RNA polymerase II promoter involved in neuron differentiation|upregulation of transcription from RNA polymerase II promoter involved in neuron differentiation|up-regulation of transcription from RNA polymerase II promoter involved in neuron differentiation|activation of transcription from RNA polymerase II promoter involved in neuron differentiation|stimulation of transcription from RNA polymerase II promoter involved in neuron differentiation|positive regulation of global transcription from Pol II promoter involved in neuron differentiation|up-regulation of global transcription from RNA polymerase II promoter involved in neuron differentiation|stimulation of global transcription from RNA polymerase II promoter involved in neuron differentiation|up regulation of global transcription from RNA polymerase II promoter involved in neuron differentiation							kmv	2015-03-24T20:15:59Z					biological_process											owl:Class	
GO:0047381	biolink:NamedThing	dodecanoyl-[acyl-carrier-protein] hydrolase activity	Catalysis of the reaction: H2O + dodecanoyl-[acyl-carrier protein] = dodecanoate + [acyl-carrier protein].	tmpzr1t_l9r_go_relaxed.owl	dodecyl-[acyl-carrier protein] hydrolase activity|lauroyl-[acyl-carrier-protein] hydrolase activity|lauryl-[acyl-carrier protein] hydrolase activity|lauryl-acyl-carrier protein hydrolase activity|lauroyl-ACP hydrolase activity|dodecanoyl-acyl-carrier-protein hydrolase activity|dodecyl-acyl-carrier protein hydrolase|dodecanoyl-ACP hydrolase activity|dodecanoyl-[acyl-carrier protein] hydrolase activity|lauryl-acyl-carrier-protein hydrolase activity				RHEA:30119|MetaCyc:3.1.2.21-RXN|EC:3.1.2.21							GO:0016294		molecular_function											owl:Class	
GO:0004908	biolink:NamedThing	interleukin-1 receptor activity	Combining with interleukin-1 to initiate a change in cell activity. Interleukin-1 is produced mainly by activated macrophages and is involved in the inflammatory response.	tmpzr1t_l9r_go_relaxed.owl	IL-1R|IL-1 receptor activity				Wikipedia:Interleukin-1_receptor									molecular_function											owl:Class	
GO:0072713	biolink:NamedThing	cellular response to thiabendazole	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a thiabendazole stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to TBZ							mah	2012-04-11T04:24:19Z					biological_process											owl:Class	
GO:0061964	biolink:NamedThing	negative regulation of entry into reproductive diapause	Any process that stops, prevents, or reduces the frequency, rate or extent of the dormancy process that results in entry into reproductive diapause. Reproductive diapause is a form of diapause where the organism itself will remain fully active, including feeding and other routine activities, but the reproductive organs experience a tissue-specific reduction in metabolism, with characteristic triggering and releasing stimuli.	tmpzr1t_l9r_go_relaxed.owl								dph	2018-02-05T15:04:33Z					biological_process											owl:Class	
GO:0046568	biolink:NamedThing	3-methylbutanol:NAD(P) oxidoreductase activity	Catalysis of the reaction: 3-methylbutanol + NAD(P)+ = 3-methylbutanal + NAD(P)H + H+. 3-methylbutanal is also known as isovaleraldehyde.	tmpzr1t_l9r_go_relaxed.owl	3-methylbutyraldehyde reductase activity|3-methylbutanal reductase [NAD(P)] activity|isoamyl alcohol oxidase activity				MetaCyc:1.1.1.265-RXN|EC:1.1.1.265									molecular_function											owl:Class	
GO:0018455	biolink:NamedThing	alcohol dehydrogenase [NAD(P)+] activity	Catalysis of the reaction: an alcohol + NAD(P)+ = an aldehyde + NAD(P)H + H+.	tmpzr1t_l9r_go_relaxed.owl	alcohol:NAD(P)+ oxidoreductase activity|aldehyde reductase (NADPH/NADH)				RHEA:10736|EC:1.1.1.71|MetaCyc:ALCOHOL-DEHYDROGENASE-NADP+-RXN|UM-BBD_reactionID:r0172									molecular_function											owl:Class	
GO:0032824	biolink:NamedThing	negative regulation of natural killer cell differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	inhibition of natural killer cell differentiation|negative regulation of NK cell differentiation|down regulation of natural killer cell differentiation|downregulation of natural killer cell differentiation|down-regulation of natural killer cell differentiation|negative regulation of natural killer cell development					Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.								biological_process											owl:Class	
GO:0072133	biolink:NamedThing	metanephric mesenchyme morphogenesis	The process in which the anatomical structures of a metanephric mesenchymal tissue are generated and organized. Metanephric mesenchyme is the tissue made up of loosely connected mesenchymal cells in the metanephros.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-02-22T02:20:14Z					biological_process											owl:Class	
GO:0080028	biolink:NamedThing	nitrile biosynthetic process	The chemical reactions and pathways resulting in the formation of a nitrile, an organic compound containing trivalent nitrogen attached to one carbon atom.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0006183	biolink:NamedThing	GTP biosynthetic process	The chemical reactions and pathways resulting in the formation of GTP, guanosine triphosphate.	tmpzr1t_l9r_go_relaxed.owl	GTP synthesis|GTP biosynthesis|GTP formation|GTP anabolism													biological_process											owl:Class	
GO:0009206	biolink:NamedThing	purine ribonucleoside triphosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of purine ribonucleoside triphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with triphosphate on the sugar.	tmpzr1t_l9r_go_relaxed.owl	purine ribonucleoside triphosphate formation|purine ribonucleoside triphosphate anabolism|purine ribonucleoside triphosphate biosynthesis|purine ribonucleoside triphosphate synthesis													biological_process											owl:Class	
GO:0048494	biolink:NamedThing	chromatophore ribulose bisphosphate carboxylase complex	A complex, located in the chromatophore, containing either both large and small subunits or just small subunits which carries out the activity of producing 3-phosphoglycerate from carbon dioxide and ribulose-1,5-bisphosphate.	tmpzr1t_l9r_go_relaxed.owl	RubisCO complex													cellular_component											owl:Class	
GO:2000838	biolink:NamedThing	negative regulation of androstenedione secretion	Any process that stops, prevents or reduces the frequency, rate or extent of androstenedione secretion.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of androst-4-ene-3,17-dione secretion							bf	2011-07-26T08:40:40Z					biological_process											owl:Class	
GO:0020005	biolink:NamedThing	symbiont-containing vacuole membrane	The lipid bilayer surrounding a symbiont-containing vacuole, derived from both the host and symbiont.	tmpzr1t_l9r_go_relaxed.owl	parasitophorous vacuolar membrane													cellular_component											owl:Class	
GO:1905096	biolink:NamedThing	positive regulation of apolipoprotein A-I-mediated signaling pathway	Any process that activates or increases the frequency, rate or extent of apolipoprotein A-I-mediated signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	activation of apolipoprotein A-I-mediated signalling pathway|upregulation of apolipoprotein A-I-mediated signaling pathway|up-regulation of apolipoprotein A-I-mediated signaling pathway|up-regulation of apolipoprotein A-I-mediated signalling pathway|activation of apolipoprotein A-I-mediated signaling pathway|up regulation of apolipoprotein A-I-mediated signaling pathway|up regulation of apolipoprotein A-I-mediated signalling pathway|positive regulation of apolipoprotein A-I-mediated signalling pathway|upregulation of apolipoprotein A-I-mediated signalling pathway							bc	2016-03-31T11:34:07Z					biological_process											owl:Class	
GO:0070228	biolink:NamedThing	regulation of lymphocyte apoptotic process	Any process that modulates the occurrence or rate of lymphocyte death by apoptotic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of lymphocyte apoptosis					Note that a lymphocyte is a cell of the B cell, T cell, or natural killer cell lineage (CL:0000542).								biological_process											owl:Class	
GO:0018053	biolink:NamedThing	C-terminal peptidyl-valine amidation	The formation of a C-terminal peptidyl-valine amide by hydrolysis and oxidation of an interior Val-Gly peptide in a secreted protein.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0100									biological_process											owl:Class	
GO:0015030	biolink:NamedThing	Cajal body	A class of nuclear body, first seen after silver staining by Ramon y Cajal in 1903, enriched in small nuclear ribonucleoproteins, and certain general RNA polymerase II transcription factors; ultrastructurally, they appear as a tangle of coiled, electron-dense threads roughly 0.5 micrometers in diameter; involved in aspects of snRNP biogenesis; the protein coilin serves as a marker for Cajal bodies. Some argue that Cajal bodies are the sites for preassembly of transcriptosomes, unitary particles involved in transcription and processing of RNA.	tmpzr1t_l9r_go_relaxed.owl	Gemini of coiled bodies|coiled body|Gems				Wikipedia:Cajal_body|NIF_Subcellular:nlx_subcell_090901									cellular_component											owl:Class	
GO:0031232	biolink:NamedThing	extrinsic component of external side of plasma membrane	The component of a plasma membrane consisting of gene products and protein complexes that are loosely bound to its external surface, but not integrated into the hydrophobic region.	tmpzr1t_l9r_go_relaxed.owl	extrinsic to external leaflet of plasma membrane|extrinsic to external side of plasma membrane													cellular_component											owl:Class	
GO:0140447	biolink:NamedThing	cytokine precursor processing	The cleavage of a peptide bond in a precursor form of a cytokine, resulting in the mature (active) form of the cytokine.	tmpzr1t_l9r_go_relaxed.owl	interleukin maturation|interleukin processing	https://github.com/geneontology/go-ontology/issues/19216						pg	2020-04-03T12:49:29Z					biological_process											owl:Class	
GO:0099186	biolink:NamedThing	structural constituent of postsynapse	The action of a molecule that contributes to the structural integrity of a postsynapse.	tmpzr1t_l9r_go_relaxed.owl								dos	2017-12-20T14:54:33Z					molecular_function											owl:Class	
GO:0036099	biolink:NamedThing	female germ-line stem cell population maintenance	The process by which an organism or tissue maintains a population of female germ-line stem cells.	tmpzr1t_l9r_go_relaxed.owl								bf	2012-01-26T01:58:10Z					biological_process											owl:Class	
GO:2001166	biolink:NamedThing	regulation of histone H2B ubiquitination	Any process that modulates the frequency, rate or extent of histone H2B ubiquitination.	tmpzr1t_l9r_go_relaxed.owl								se	2011-10-25T10:49:51Z					biological_process											owl:Class	
GO:0009233	biolink:NamedThing	menaquinone metabolic process	The chemical reactions and pathways involving any of the menaquinones, quinone-derived compounds synthesized by intestinal bacteria. Structurally, menaquinones consist of a methylated naphthoquinone ring structure and side chains composed of a variable number of unsaturated isoprenoid residues. Menaquinones have vitamin K activity and are known as vitamin K2.	tmpzr1t_l9r_go_relaxed.owl	multiprenylmenaquinone metabolic process|menatetrenone metabolic process|menaquinone metabolism|multiprenylmenaquinone metabolism|vitamin K2 metabolic process|vitamin K2 metabolism|menatetrenone metabolism													biological_process											owl:Class	
GO:0045068	biolink:NamedThing	negative extrathymic T cell selection	The process of elimination of extrathymically maturing T cells which react strongly with self-antigens.	tmpzr1t_l9r_go_relaxed.owl	negative extrathymic T lymphocyte selection|negative extrathymic T-cell selection|negative extrathymic T-lymphocyte selection													biological_process											owl:Class	
GO:0046919	biolink:NamedThing	pyruvyltransferase activity	Catalysis of the transfer of a pyruvyl (oxopropanoyl) group from one compound to another.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0050058	biolink:NamedThing	linoleate isomerase activity	Catalysis of the reaction: linoleate = 9-cis,11-trans-octadecadienoate.	tmpzr1t_l9r_go_relaxed.owl	linoleic acid isomerase activity|linoleate delta12-cis-delta11-trans-isomerase activity				KEGG_REACTION:R03627|MetaCyc:LINOLEATE-ISOMERASE-RXN|RHEA:17381|EC:5.2.1.5									molecular_function											owl:Class	
GO:0036055	biolink:NamedThing	protein-succinyllysine desuccinylase activity	Catalysis of the reaction: H2O + N(6)-succinyl-L-lysyl-[protein] + NAD(+) = 2''-O-succinyl-ADP-D-ribose + L-lysyl-[protein] + nicotinamide.	tmpzr1t_l9r_go_relaxed.owl	peptidyl-succinyllysine desuccinylase activity|succinyllysine desuccinylase activity|succinyl lysine desuccinylase activity				RHEA:47668	This reaction is the removal of a succinyl group (CO-CH2-CH2-CO) from a succinylated lysine residue of a protein or peptide.		bf	2011-12-12T01:33:51Z					molecular_function											owl:Class	
GO:0038045	biolink:NamedThing	large latent transforming growth factor-beta complex	A protein complex containing latency-associated proteins (LAPs), mature disulphide-linked dimeric TGF-beta, and latent TGF-beta binding proteins (LTBPs). TGF-beta is mostly secreted as part of the large latent complex, and must be subsequently released from the LLC in order to bind to cell surface receptors.	tmpzr1t_l9r_go_relaxed.owl	large latent complex|LLC							bf	2011-11-03T04:29:49Z					cellular_component											owl:Class	
GO:0099021	biolink:NamedThing	cortical endoplasmic reticulum lumen	The volume enclosed by the membranes of the cortical endoplasmic reticulum.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0031005	biolink:NamedThing	filamin binding	Binding to a filamin, any member of a family of high molecular mass cytoskeletal proteins that crosslink actin filaments to form networks and stress fibers. Filamins contain an amino-terminal alpha-actinin-like actin binding domain, which is followed by a rod-domain composed of 4 to 24 100-residue repetitive segments including a carboxy-terminal dimerization domain.	tmpzr1t_l9r_go_relaxed.owl	filamin B binding|filamin C binding|beta-filamin binding|filamin-2 binding|filamin-B binding|alpha-filamin binding|ABPL binding|filamin-1 binding|filamin-A binding|gamma-filamin binding|ABP-278/276 binding|filamin-3 binding|filamin-C binding|ABP-280 binding|filamin A binding											GO:0031006|GO:0031007|GO:0031008		molecular_function											owl:Class	
GO:2001060	biolink:NamedThing	D-glycero-D-manno-heptose 7-phosphate metabolic process	The chemical reactions and pathways involving a D-glycero-D-manno-heptose 7-phosphate.	tmpzr1t_l9r_go_relaxed.owl	D-glycero-D-manno-heptose 7-phosphate metabolism							jl	2011-09-09T03:29:03Z					biological_process											owl:Class	
GO:2001311	biolink:NamedThing	lysobisphosphatidic acid metabolic process	The chemical reactions and pathways involving a lysobisphosphatidic acid. A lysobisphosphatidic acid is a lysophosphatidic acid having the unusual property of a phosphodiester moiety linked to positions sn-1 and sn1' of glycerol; and two additional fatty acids esterified to the glycerol head group.	tmpzr1t_l9r_go_relaxed.owl	bis(monoacylglycerol) hydrogen phosphate (BMP) metabolism|bis(monoacylglycerol) hydrogen phosphate (BMP) metabolic process|bis(monoacylglycerol) hydrogen phosphate metabolism|lysobisphosphatidic acid metabolism|bis(monoacylglycerol) hydrogen phosphate metabolic process|LBPA metabolic process|LBPA metabolism							bf	2012-03-16T09:31:27Z					biological_process											owl:Class	
GO:1901290	biolink:NamedThing	succinyl-CoA biosynthetic process	The chemical reactions and pathways resulting in the formation of succinyl-CoA.	tmpzr1t_l9r_go_relaxed.owl	succinyl-CoA anabolism|succinyl-CoA formation|succinyl-CoA biosynthesis|succinyl-CoA synthesis							yaf	2012-08-17T16:13:57Z					biological_process											owl:Class	
GO:0070429	biolink:NamedThing	negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway	Any process that stops, prevents, or reduces the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing 1 (NOD1) pathway.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of nucleotide-binding oligomerization domain containing 1 signalling pathway|negative regulation of NOD1 signaling pathway													biological_process											owl:Class	
GO:0007276	biolink:NamedThing	gamete generation	The generation and maintenance of gametes in a multicellular organism. A gamete is a haploid reproductive cell.	tmpzr1t_l9r_go_relaxed.owl	gametogenesis											GO:0009552		biological_process											owl:Class	
GO:0071184	biolink:NamedThing	protocadherin-alpha-v4-protocadherin-gamma-a1 complex	A protein complex that contains the cell adhesion molecules protocadherin-alpha-v4 and protocadherin-gamma-a1, and is involved in the regulation of protein localization to the plasma membrane.	tmpzr1t_l9r_go_relaxed.owl	Pcdhga1-Pcdha4 complex							mah	2009-11-23T04:11:47Z					cellular_component											owl:Class	
GO:0006196	biolink:NamedThing	AMP catabolic process	The chemical reactions and pathways resulting in the breakdown of AMP, adenosine monophosphate.	tmpzr1t_l9r_go_relaxed.owl	AMP degradation|AMP breakdown|AMP catabolism													biological_process											owl:Class	
GO:0009169	biolink:NamedThing	purine ribonucleoside monophosphate catabolic process	The chemical reactions and pathways resulting in the breakdown of purine ribonucleoside monophosphate, a compound consisting of a purine base linked to a ribose sugar esterified with phosphate on the sugar.	tmpzr1t_l9r_go_relaxed.owl	purine ribonucleoside monophosphate catabolism|purine ribonucleoside monophosphate degradation|purine ribonucleoside monophosphate breakdown													biological_process											owl:Class	
GO:0007099	biolink:NamedThing	centriole replication	The cell cycle process in which a daughter centriole is formed perpendicular to an existing centriole. An immature centriole contains a ninefold radially symmetric array of single microtubules; mature centrioles consist of a radial array of nine microtubule triplets, doublets, or singlets depending upon the species and cell type. Duplicated centrioles also become the ciliary basal body in cells that form cilia during G0.	tmpzr1t_l9r_go_relaxed.owl	microtubule basal body duplication|ciliary basal body duplication|centriole duplication											GO:0032054		biological_process											owl:Class	
GO:2000059	biolink:NamedThing	negative regulation of ubiquitin-dependent protein catabolic process	Any process that stops, prevents, or reduces the frequency, rate or extent of ubiquitin-dependent protein catabolic process.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of protein ubiquitylation during ubiquitin-dependent protein catabolism|negative regulation of protein ubiquitination during ubiquitin-dependent protein catabolic process|negative regulation of protein ubiquitinylation during ubiquitin-dependent protein catabolic process|negative regulation of protein ubiquitination during ubiquitin-dependent protein breakdown|negative regulation of protein degradation tagging activity|negative regulation of protein ubiquitinylation during ubiquitin-dependent protein catabolism|negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process|negative regulation of protein ubiquitination during ubiquitin-dependent protein degradation|negative regulation of protein ubiquitination during ubiquitin-dependent protein catabolism|negative regulation of protein ubiquitylation during ubiquitin-dependent protein catabolic process							jl	2010-08-20T01:23:56Z					biological_process											owl:Class	
GO:0033143	biolink:NamedThing	regulation of intracellular steroid hormone receptor signaling pathway	Any process that modulates the frequency, rate or extent of the activity of any intracellular steroid hormone receptor signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	regulation of steroid hormone receptor signaling pathway|regulation of steroid hormone receptor signalling pathway													biological_process											owl:Class	
GO:0009958	biolink:NamedThing	positive gravitropism	The orientation of plant parts towards gravity.	tmpzr1t_l9r_go_relaxed.owl	root gravitropism													biological_process											owl:Class	
GO:0009630	biolink:NamedThing	gravitropism	The orientation of plant parts under the stimulation of gravity.	tmpzr1t_l9r_go_relaxed.owl	geotropism				Wikipedia:Gravitropism									biological_process											owl:Class	
GO:1903276	biolink:NamedThing	regulation of sodium ion export across plasma membrane	Any process that modulates the frequency, rate or extent of sodium ion export across the plasma membrane.	tmpzr1t_l9r_go_relaxed.owl	regulation of sodium export|regulation of sodium ion export from cell|regulation of sodium ion export							rl	2014-08-08T17:06:46Z			GO:1903273		biological_process											owl:Class	
GO:0098592	biolink:NamedThing	cytoplasmic side of apical plasma membrane	The side (leaflet) of the apical region of the plasma membrane that faces the cytoplasm.	tmpzr1t_l9r_go_relaxed.owl								dos	2014-03-06T12:07:32Z					cellular_component											owl:Class	
GO:0048282	biolink:NamedThing	determinate inflorescence morphogenesis	The process in which the anatomical structures of determinate inflorescences are generated and organized. A determinate inflorescence is one that can only produce a predetermined number of floral meristems.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0071042	biolink:NamedThing	nuclear polyadenylation-dependent mRNA catabolic process	The chemical reactions and pathways occurring in the nucleus and resulting in the breakdown of a messenger RNA (mRNA) molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target mRNA.	tmpzr1t_l9r_go_relaxed.owl	nuclear poly(A)-dependent mRNA catabolic process							krc	2009-07-29T02:06:19Z					biological_process											owl:Class	
GO:0071047	biolink:NamedThing	polyadenylation-dependent mRNA catabolic process	The chemical reactions and pathways resulting in the breakdown of a messenger RNA (mRNA) molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target mRNA.	tmpzr1t_l9r_go_relaxed.owl	poly(A)-dependent mRNA catabolic process	https://github.com/geneontology/go-ontology/issues/20568						krc	2009-08-07T09:57:56Z					biological_process											owl:Class	
GO:0035333	biolink:NamedThing	Notch receptor processing, ligand-dependent	The proteolytic cleavages to the Notch protein that occur as a result of ligand binding. Ligand binding at the cell surface exposes an otherwise inaccessible cleavage site in the extracellular portion of Notch, which when cleaved releases a membrane-tethered form of the Notch intracellular domain. Subsequent cleavage within the transmembrane domain then leads to the release of the soluble Notch intracellular domain (NICD).	tmpzr1t_l9r_go_relaxed.owl	Notch S2 cleavage|Notch S3 cleavage							bf	2010-02-26T02:31:31Z					biological_process											owl:Class	
GO:0031293	biolink:NamedThing	membrane protein intracellular domain proteolysis	The proteolytic cleavage of a transmembrane protein leading to the release of an intracellular domain.	tmpzr1t_l9r_go_relaxed.owl	membrane protein solubilization													biological_process											owl:Class	
GO:1904818	biolink:NamedThing	visceral peritoneum development	The process whose specific outcome is the progression of a visceral peritoneum over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl								dph	2015-11-17T19:00:17Z					biological_process											owl:Class	
GO:0072687	biolink:NamedThing	meiotic spindle	A spindle that forms as part of meiosis. Several proteins, such as budding yeast Spo21p, fission yeast Spo2 and Spo13, and C. elegans mei-1, localize specifically to the meiotic spindle and are absent from the mitotic spindle.	tmpzr1t_l9r_go_relaxed.owl								mah	2011-07-08T05:17:08Z					cellular_component											owl:Class	
GO:1901870	biolink:NamedThing	ecgonone methyl ester metabolic process	The chemical reactions and pathways involving ecgonone methyl ester.	tmpzr1t_l9r_go_relaxed.owl	ecgonone methyl ester metabolism							ms	2013-02-04T11:58:30Z					biological_process											owl:Class	
GO:0042213	biolink:NamedThing	m-cresol catabolic process	The chemical reactions and pathways resulting in the breakdown of m-cresol (3-hydroxytoluene), the meta-isoform of cresol.	tmpzr1t_l9r_go_relaxed.owl	m-cresol degradation|3-hydroxytoluene catabolic process|3-hydroxytoluene catabolism|meta-cresol catabolism|m-cresol catabolism|meta-cresol catabolic process|m-cresol breakdown				UM-BBD_pathwayID:mcr|MetaCyc:M-CRESOL-DEGRADATION-PWY									biological_process											owl:Class	
GO:0008089	biolink:NamedThing	anterograde axonal transport	The directed movement of organelles or molecules along microtubules from the cell body toward the cell periphery in nerve cell axons.	tmpzr1t_l9r_go_relaxed.owl	anterograde axon cargo transport													biological_process											owl:Class	
GO:1903939	biolink:NamedThing	regulation of TORC2 signaling	Any process that modulates the frequency, rate or extent of TORC2 signaling.	tmpzr1t_l9r_go_relaxed.owl	regulation of TORC2 signal transduction							al	2015-02-16T18:28:39Z					biological_process											owl:Class	
GO:2000128	biolink:NamedThing	regulation of octopamine signaling pathway	Any process that modulates the frequency, rate or extent of octopamine signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	regulation of octopamine signalling pathway							mah	2010-09-29T09:29:41Z					biological_process											owl:Class	
GO:2000125	biolink:NamedThing	regulation of octopamine or tyramine signaling pathway	Any process that modulates the frequency, rate or extent of octopamine or tyramine signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	regulation of octopamine or tyramine signalling pathway|regulation of octopamine/tyramine signaling pathway							mah	2010-09-29T09:27:12Z					biological_process											owl:Class	
GO:1901183	biolink:NamedThing	positive regulation of camalexin biosynthetic process	Any process that activates or increases the frequency, rate or extent of camalexin biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	up regulation of camalexin synthesis|positive regulation of camalexin synthesis|up-regulation of camalexin biosynthetic process|upregulation of camalexin biosynthetic process|upregulation of camalexin formation|activation of camalexin biosynthesis|up regulation of camalexin anabolism|activation of camalexin formation|up-regulation of camalexin synthesis|up regulation of camalexin formation|activation of camalexin biosynthetic process|activation of camalexin anabolism|positive regulation of camalexin formation|up-regulation of camalexin formation|positive regulation of camalexin anabolism|up regulation of camalexin biosynthesis|upregulation of camalexin synthesis|positive regulation of camalexin biosynthesis|upregulation of camalexin biosynthesis|up regulation of camalexin biosynthetic process|activation of camalexin synthesis|up-regulation of camalexin anabolism|upregulation of camalexin anabolism|up-regulation of camalexin biosynthesis							tb	2012-07-23T02:17:21Z					biological_process											owl:Class	
GO:2000798	biolink:NamedThing	negative regulation of amniotic stem cell differentiation	Any process that stops, prevents or reduces the frequency, rate or extent of amniotic stem cell differentiation.	tmpzr1t_l9r_go_relaxed.owl								yaf	2011-06-29T02:19:03Z					biological_process											owl:Class	
GO:0010495	biolink:NamedThing	long-distance posttranscriptional gene silencing	A posttranscriptional gene silencing process in which the silencing signal originates in a tissue separate from the tissue in which the silencing takes place.	tmpzr1t_l9r_go_relaxed.owl	long-distance propagation of posttranscriptional gene silencing													biological_process											owl:Class	
GO:0018102	biolink:NamedThing	peptidyl-arginine hydroxylation to peptidyl-4-hydroxy-L-arginine	The hydroxylation of peptidyl-arginine to form peptidyl-4-hydroxy-L-arginine.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0215									biological_process											owl:Class	
GO:0030961	biolink:NamedThing	peptidyl-arginine hydroxylation	The hydroxylation of peptidyl-arginine to form peptidyl-hydroxyarginine.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0061959	biolink:NamedThing	response to (R)-carnitine	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an (R)-carnitine stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to L-carnitine							dph	2018-01-19T13:31:39Z					biological_process											owl:Class	
GO:1901266	biolink:NamedThing	cephalosporin C metabolic process	The chemical reactions and pathways involving cephalosporin C.	tmpzr1t_l9r_go_relaxed.owl	cephalosporin C metabolism							yaf	2012-08-17T14:25:59Z					biological_process											owl:Class	
GO:0043645	biolink:NamedThing	cephalosporin metabolic process	The chemical reactions and pathways involving a cephalosporin, any of large class of tetracyclic triterpene broad-spectrum antibiotics similar both chemically and in their mode of action to penicillin, first isolated from the culture filtrates of mediterranean fungus acremonium (cephalosporium acremonium), and effective against gram-positive bacteria.	tmpzr1t_l9r_go_relaxed.owl	cephalosporin metabolism													biological_process											owl:Class	
GO:2001224	biolink:NamedThing	positive regulation of neuron migration	Any process that activates or increases the frequency, rate or extent of neuron migration.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of neuron guidance|positive regulation of neuron chemotaxis|positive regulation of neuronal migration							kmv	2011-11-17T10:01:49Z					biological_process											owl:Class	
GO:0099510	biolink:NamedThing	calcium ion binding involved in regulation of cytosolic calcium ion concentration	The directed change of cytosolic calcium ion concentration in the cytosol via the reversible binding of calcium ions to calcium-binding proteins in the cytosol thereby modulating the spatial and temporal dynamics of changes in cytosolic calcium concentrations.	tmpzr1t_l9r_go_relaxed.owl	regulation of cytosolic calcium ion concentration by calcium ion buffering													molecular_function											owl:Class	
GO:0044857	biolink:NamedThing	plasma membrane raft organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of plasma membrane rafts.	tmpzr1t_l9r_go_relaxed.owl								jl	2014-07-23T16:20:07Z					biological_process											owl:Class	
GO:0032999	biolink:NamedThing	Fc-alpha receptor I complex	A protein complex composed of an Fc-alpha R alpha chain and an Fc-epsilon RI gamma chain dimer with or without additional signaling components. The complex functions primarily as an activating receptor for IgA.	tmpzr1t_l9r_go_relaxed.owl	IgA receptor complex|immunoglobulin A receptor complex|FcaRI complex													cellular_component											owl:Class	
GO:0050567	biolink:NamedThing	glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity	Catalysis of the reaction: L-glutamine + glutamyl-tRNA(Gln) + ATP = L-glutamate + glutaminyl-tRNA(Gln) + phosphate + ADP.	tmpzr1t_l9r_go_relaxed.owl	glutamyl-tRNAGln:L-glutamine amido-ligase (ADP-forming)|glutamyl-tRNAGln amidotransferase activity|Glu-AdT activity|glutamyl-tRNA(Gln) amidotransferase activity|Glu-tRNA(Gln) amidotransferase activity|Glu-tRNAGln amidotransferase activity|Glu-tRNAGln:L-glutamine amido-ligase (ADP-forming)|glutaminyl-tRNA synthase (glutamine-hydrolysing)				RHEA:17521|EC:6.3.5.7|Wikipedia:Glutaminyl-tRNA_synthase_(glutamine-hydrolysing)|MetaCyc:6.3.5.7-RXN							GO:0008264|GO:0017068		molecular_function											owl:Class	
GO:0007348	biolink:NamedThing	regulation of syncytial blastoderm mitotic cell cycle	A cell cycle process that modulates the rate or extent of the progression through the syncytial blastoderm mitotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl	regulation of syncytial blastoderm cell cycle|regulation of syncytial blastoderm cell cycle progression|modulation of syncytial blastoderm cell cycle progression|syncytial blastoderm cell cycle modulation|syncytial blastoderm cell cycle regulator|syncytial blastoderm cell cycle regulation|regulation of progression through syncytial blastoderm mitotic cell cycle													biological_process											owl:Class	
GO:0060744	biolink:NamedThing	mammary gland branching involved in thelarche	The process in which the branching structure of the mammary gland duct is generated and organized during the period of sexual maturity in mammals. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk.	tmpzr1t_l9r_go_relaxed.owl	mammary gland branching involved in puberty							dph	2009-06-22T08:12:17Z					biological_process											owl:Class	
GO:0048346	biolink:NamedThing	positive regulation of paraxial mesodermal cell fate determination	Any process that activates or increases the frequency, rate or extent of paraxial mesoderm cell fate determination.	tmpzr1t_l9r_go_relaxed.owl	activation of paraxial mesodermal cell fate determination|upregulation of paraxial mesodermal cell fate determination|up regulation of paraxial mesodermal cell fate determination|stimulation of paraxial mesodermal cell fate determination|up-regulation of paraxial mesodermal cell fate determination													biological_process											owl:Class	
GO:0048345	biolink:NamedThing	regulation of paraxial mesodermal cell fate determination	Any process that modulates the frequency, rate or extent of paraxial mesoderm cell fate determination.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0030118	biolink:NamedThing	clathrin coat	A membrane coat found on coated pits and some coated vesicles; consists of polymerized clathrin triskelions, each comprising three clathrin heavy chains and three clathrin light chains, linked to the membrane via one of the AP adaptor complexes.	tmpzr1t_l9r_go_relaxed.owl	clathrin cage				NIF_Subcellular:sao879919129|Wikipedia:Clathrin							GO:0016190		cellular_component											owl:Class	
GO:1900892	biolink:NamedThing	positive regulation of pentadecane metabolic process	Any process that activates or increases the frequency, rate or extent of pentadecane metabolic process.	tmpzr1t_l9r_go_relaxed.owl	up regulation of pentadecane metabolism|up regulation of pentadecane metabolic process|upregulation of pentadecane metabolic process|up-regulation of pentadecane metabolic process|up-regulation of pentadecane metabolism|upregulation of pentadecane metabolism|activation of pentadecane metabolism|activation of pentadecane metabolic process|positive regulation of pentadecane metabolism							tt	2012-06-13T03:06:20Z					biological_process											owl:Class	
GO:0015706	biolink:NamedThing	nitrate transport	The directed movement of nitrate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	low affinity nitrate transport|low-affinity nitrate transport											GO:0080055|GO:0006872		biological_process											owl:Class	
GO:0090513	biolink:NamedThing	L-histidine transmembrane import into vacuole	The directed movement of L-histidine into the vacuole across the vacuolar membrane.	tmpzr1t_l9r_go_relaxed.owl	vacuolar histidine import|histidine transmembrane import into vacuole							tb	2012-12-14T11:25:52Z			GO:0090457		biological_process											owl:Class	
GO:0045987	biolink:NamedThing	positive regulation of smooth muscle contraction	Any process that activates or increases the frequency, rate or extent of smooth muscle contraction.	tmpzr1t_l9r_go_relaxed.owl	stimulation of smooth muscle contraction|up-regulation of smooth muscle contraction|up regulation of smooth muscle contraction|activation of smooth muscle contraction|upregulation of smooth muscle contraction													biological_process											owl:Class	
GO:0002670	biolink:NamedThing	regulation of B cell anergy	Any process that modulates the frequency, rate, or extent of B cell anergy.	tmpzr1t_l9r_go_relaxed.owl	regulation of B-lymphocyte anergy|regulation of B lymphocyte anergy|regulation of B-cell anergy													biological_process											owl:Class	
GO:0071052	biolink:NamedThing	alpha9-beta1 integrin-ADAM1 complex	A protein complex that consists of an alpha9-beta1 integrin complex bound to the transmembrane metallopeptidase ADAM1.	tmpzr1t_l9r_go_relaxed.owl	ITGA9-ITGB1-ADAM1 complex							mah	2009-11-03T03:55:15Z					cellular_component											owl:Class	
GO:0061743	biolink:NamedThing	motor learning	Any process in which an organism acquires a novel neuromuscular action or movement as the result of experience.	tmpzr1t_l9r_go_relaxed.owl								dph	2015-11-09T12:40:29Z					biological_process											owl:Class	
GO:0047110	biolink:NamedThing	phenylglyoxylate dehydrogenase (acylating) activity	Catalysis of the reaction: CoA + NAD(+) + phenylglyoxylate = benzoyl-CoA + CO(2) + NADH.	tmpzr1t_l9r_go_relaxed.owl	phenylglyoxylate:NAD+ oxidoreductase activity				MetaCyc:1.2.1.58-RXN|RHEA:10372|KEGG_REACTION:R02450|EC:1.2.1.58									molecular_function											owl:Class	
GO:0045593	biolink:NamedThing	negative regulation of cumulus cell differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of ovarian cumulus cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	down regulation of cumulus cell differentiation|negative regulation of ovarian cumulus cell differentiation|inhibition of cumulus cell differentiation|downregulation of cumulus cell differentiation|down-regulation of cumulus cell differentiation													biological_process											owl:Class	
GO:0035691	biolink:NamedThing	macrophage migration inhibitory factor signaling pathway	A series of molecular signals initiated by the binding of macrophage migration inhibitory factor to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.	tmpzr1t_l9r_go_relaxed.owl	MIF signaling pathway|macrophage migration inhibitory factor signalling pathway							bf	2011-02-25T11:31:21Z					biological_process											owl:Class	
GO:0032379	biolink:NamedThing	positive regulation of intracellular lipid transport	Any process that activates or increases the frequency, rate or extent of the directed movement of lipids within cells.	tmpzr1t_l9r_go_relaxed.owl	activation of intracellular lipid transport|stimulation of intracellular lipid transport|up regulation of intracellular lipid transport|up-regulation of intracellular lipid transport|upregulation of intracellular lipid transport													biological_process											owl:Class	
GO:1900331	biolink:NamedThing	negative regulation of methane biosynthetic process from trimethylamine	Any process that stops, prevents or reduces the frequency, rate or extent of methane biosynthetic process from trimethylamine.	tmpzr1t_l9r_go_relaxed.owl	down regulation of methane biosynthetic process from trimethylamine|down-regulation of methane biosynthetic process from trimethylamine|inhibition of methane biosynthetic process from trimethylamine|downregulation of methane biosynthetic process from trimethylamine							tt	2012-04-06T01:53:12Z					biological_process											owl:Class	
GO:0000247	biolink:NamedThing	C-8 sterol isomerase activity	Catalysis of the reaction which results in unsaturation at C-7 in the B ring of sterols.	tmpzr1t_l9r_go_relaxed.owl	delta-8-delta-7 sterol isomerase activity													molecular_function											owl:Class	
GO:0009525	biolink:NamedThing	phragmosome	A flattened membranous vesicle containing cell wall components.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Phragmosome									cellular_component											owl:Class	
GO:1900242	biolink:NamedThing	regulation of synaptic vesicle endocytosis	Any process that modulates the frequency, rate or extent of synaptic vesicle endocytosis.	tmpzr1t_l9r_go_relaxed.owl	regulation of synaptic vesicle retrieval							rl	2012-03-28T01:40:26Z					biological_process											owl:Class	
GO:0035513	biolink:NamedThing	oxidative RNA demethylation	The removal of the methyl group from one or more nucleotides within an RNA molecule involving oxidation (i.e. electron loss) of one or more atoms.	tmpzr1t_l9r_go_relaxed.owl								bf	2010-04-30T02:25:35Z					biological_process											owl:Class	
GO:1905301	biolink:NamedThing	regulation of macropinocytosis	Any process that modulates the frequency, rate or extent of macropinocytosis.	tmpzr1t_l9r_go_relaxed.owl	regulation of clathrin-independent pinocytosis							pad	2016-07-04T14:16:32Z					biological_process											owl:Class	
GO:0043518	biolink:NamedThing	negative regulation of DNA damage response, signal transduction by p53 class mediator	Any process that stops, prevents, or reduces the frequency, rate or extent of the cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of p53 induced by DNA damage response|down regulation of DNA damage response, signal transduction by p53 class mediator|down-regulation of DNA damage response, signal transduction by p53 class mediator|downregulation of DNA damage response, signal transduction by p53 class mediator|inhibition of DNA damage response, signal transduction by p53 class mediator													biological_process											owl:Class	
GO:0043516	biolink:NamedThing	regulation of DNA damage response, signal transduction by p53 class mediator	Any process that modulates the frequency, rate or extent of the cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage.	tmpzr1t_l9r_go_relaxed.owl	regulation of p53 induced by DNA damage response													biological_process											owl:Class	
GO:0045203	biolink:NamedThing	integral component of cell outer membrane	The component of the cell outer membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.	tmpzr1t_l9r_go_relaxed.owl	integral to cell outer membrane|integral to external membrane|integral to outer membrane													cellular_component											owl:Class	
GO:0060237	biolink:NamedThing	regulation of fungal-type cell wall organization	Any process that modulates the rate, frequency or extent of the formation, arrangement of constituent parts, or disassembly of the fungal-type cell wall.	tmpzr1t_l9r_go_relaxed.owl	regulation of fungal-type cell wall organization and biogenesis|regulation of fungal-type cell wall organisation													biological_process											owl:Class	
GO:0008303	biolink:NamedThing	caspase complex	A protein complex that contains one or more cysteine-type endopeptidases (also called caspases), which give the complex a peptidase activity with specificity for the hydrolysis of aspartyl bonds. These complexes may be involved e.g. in apoptotic or inflammation processes.	tmpzr1t_l9r_go_relaxed.owl	cysteine-type endopeptidase complex					Note that this term was reinstated from obsolete.								cellular_component											owl:Class	
GO:0090107	biolink:NamedThing	regulation of high-density lipoprotein particle assembly	Any process that modulates the frequency, rate, or extent of high-density lipoprotein particle assembly. High-density lipoprotein particle assembly is the aggregation and arrangement of proteins and lipids to form a high-density lipoprotein particle.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-11-25T10:50:18Z					biological_process											owl:Class	
GO:1905747	biolink:NamedThing	negative regulation of saliva secretion	Any process that stops, prevents or reduces the frequency, rate or extent of saliva secretion.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of salivation|down regulation of saliva secretion|down-regulation of saliva secretion|down-regulation of salivation|downregulation of salivation|inhibition of saliva secretion|downregulation of saliva secretion|down regulation of salivation|inhibition of salivation							pga	2016-12-09T10:24:00Z					biological_process											owl:Class	
GO:0140408	biolink:NamedThing	regulation of mRNA alternative polyadenylation	Any process that modulates the frequency, rate or extent of mRNA alternative polyadenylation.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/15389						pg	2019-12-13T12:48:14Z					biological_process											owl:Class	
GO:0032751	biolink:NamedThing	positive regulation of interleukin-27 production	Any process that activates or increases the frequency, rate, or extent of interleukin-27 production.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of IL-27 production|positive regulation of interleukin-27 anabolism|up-regulation of interleukin-27 production|upregulation of interleukin-27 production|positive regulation of interleukin-27 biosynthetic process|activation of interleukin-27 production|up regulation of interleukin-27 production|stimulation of interleukin-27 production											GO:0045539		biological_process											owl:Class	
GO:1902320	biolink:NamedThing	nuclear DNA replication DNA duplex unwinding	Any DNA duplex unwinding that is involved in nuclear cell cycle DNA replication.	tmpzr1t_l9r_go_relaxed.owl	duplex DNA melting involved in DNA replication during S phase|DNA duplex unwinding involved in DNA replication involved in S phase|DNA duplex unwinding involved in nuclear cell cycle DNA replication|DNA duplex unwinding involved in DNA replication during S phase|duplex DNA melting involved in DNA replication involved in S phase|DNA unwinding involved in DNA replication during S phase|DNA unwinding involved in DNA replication involved in S phase|DNA duplex unwinding involved in DNA replication involved in S-phase|duplex DNA melting involved in DNA replication involved in S-phase|DNA unwinding involved in DNA replication involved in S-phase|DNA unwinding involved in nuclear cell cycle DNA replication							jl	2013-07-23T14:00:49Z					biological_process											owl:Class	
GO:0043509	biolink:NamedThing	activin A complex	A nonsteroidal regulator, composed of two covalently linked inhibin beta-A subunits (sometimes known as activin beta-A or activin/inhibin beta-A).	tmpzr1t_l9r_go_relaxed.owl						Note that the actions of the activin complex are the opposite of those of the inhibin complex, which is a dimer of an inhibin beta-A or inhibin beta-B subunit and an inhibin alpha subunit. See also the cellular component term 'inhibin complex ; GO:0043511'.						GO:0048181		cellular_component											owl:Class	
GO:0098672	biolink:NamedThing	inhibition of host CRISPR-cas system by virus	A process by which a virus inhibits the CRISPR-cas system of its host.	tmpzr1t_l9r_go_relaxed.owl	anti-CRISPR|CRISPR-cas system evasion by virus|evasion by virus of CRISPR-cas system	https://github.com/geneontology/go-ontology/issues/16423			VZ:3962			dos	2017-01-16T13:38:27Z					biological_process											owl:Class	
GO:0090138	biolink:NamedThing	regulation of actin cytoskeleton organization by cell-cell adhesion	Any cell-cell adhesion process that modulates the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins.	tmpzr1t_l9r_go_relaxed.owl	regulation of actin cytoskeleton organisation by cell-cell adhesion							tb	2009-12-08T02:05:00Z					biological_process											owl:Class	
GO:0032956	biolink:NamedThing	regulation of actin cytoskeleton organization	Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins.	tmpzr1t_l9r_go_relaxed.owl	regulation of actin cytoskeleton organisation|regulation of actin cytoskeleton organization and biogenesis													biological_process											owl:Class	
GO:1904042	biolink:NamedThing	negative regulation of cystathionine beta-synthase activity	Any process that stops, prevents or reduces the frequency, rate or extent of cystathionine beta-synthase activity.	tmpzr1t_l9r_go_relaxed.owl	down regulation of serine sulfhydrase activity|inhibition of L-serine hydro-lyase (adding homocysteine; L-cystathionine-forming)|down regulation of cystathionine beta-synthase activity|inhibition of serine sulfhydrylase activity|downregulation of methylcysteine synthase activity|downregulation of L-serine hydro-lyase (adding homocysteine; L-cystathionine-forming)|inhibition of cystathionine beta-synthase activity|inhibition of serine sulfhydrase activity|inhibition of L-serine hydro-lyase (adding homocysteine)|downregulation of L-serine hydro-lyase (adding homocysteine)|downregulation of cystathionine beta-synthase activity|negative regulation of serine sulfhydrylase activity|negative regulation of beta-thionase activity|down-regulation of cystathionine beta-synthase activity|down-regulation of serine sulfhydrylase activity|down-regulation of beta-thionase activity|negative regulation of L-serine hydro-lyase (adding homocysteine; L-cystathionine-forming)|inhibition of methylcysteine synthase activity|downregulation of serine sulfhydrylase activity|inhibition of beta-thionase activity|down regulation of beta-thionase activity|down-regulation of serine sulfhydrase activity|down regulation of L-serine hydro-lyase (adding homocysteine)|negative regulation of serine sulfhydrase activity|negative regulation of L-serine hydro-lyase (adding homocysteine)|down regulation of L-serine hydro-lyase (adding homocysteine; L-cystathionine-forming)|down regulation of serine sulfhydrylase activity|negative regulation of methylcysteine synthase activity|downregulation of beta-thionase activity|down-regulation of L-serine hydro-lyase (adding homocysteine)|down-regulation of L-serine hydro-lyase (adding homocysteine; L-cystathionine-forming)|down regulation of methylcysteine synthase activity|down-regulation of methylcysteine synthase activity|downregulation of serine sulfhydrase activity							hal	2015-03-16T15:52:47Z					biological_process											owl:Class	
GO:1900338	biolink:NamedThing	positive regulation of methane biosynthetic process from carbon monoxide	Any process that activates or increases the frequency, rate or extent of methane biosynthetic process from carbon monoxide.	tmpzr1t_l9r_go_relaxed.owl	upregulation of methane biosynthetic process from carbon monoxide|up-regulation of methane biosynthetic process from carbon monoxide|up regulation of methane biosynthetic process from carbon monoxide|activation of methane biosynthetic process from carbon monoxide							tt	2012-04-06T02:03:33Z					biological_process											owl:Class	
GO:1901303	biolink:NamedThing	negative regulation of cargo loading into COPII-coated vesicle	Any process that stops, prevents or reduces the frequency, rate or extent of cargo loading into a COPII-coated vesicle.	tmpzr1t_l9r_go_relaxed.owl	down regulation of cargo selection into COPII-coated vesicle|down-regulation of cargo loading into COPII vesicle|inhibition of protein sorting into COPII-coated vesicles|inhibition of cargo loading into COPII vesicle|downregulation of COPII coat-cargo complex assembly|inhibition of cargo loading into COPII-coated vesicle|down regulation of COPII coat-cargo complex assembly|downregulation of cargo loading into COPII-coated vesicle|down regulation of cargo loading into COPII vesicle|inhibition of cargo selection into COPII-coated vesicle|downregulation of cargo selection into COPII-coated vesicle|negative regulation of cargo selection into COPII-coated vesicle|inhibition of COPII vesicle protein binding|down-regulation of cargo loading into COPII-coated vesicle|negative regulation of cargo loading into COPII vesicle|downregulation of cargo loading into COPII vesicle|down regulation of cargo loading into COPII-coated vesicle|negative regulation of COPII coat-cargo complex assembly|down-regulation of cargo selection into COPII-coated vesicle|inhibition of COPII coat-cargo complex assembly|down-regulation of COPII coat-cargo complex assembly							bf	2012-08-21T13:05:46Z					biological_process											owl:Class	
GO:0002451	biolink:NamedThing	peripheral B cell tolerance induction	Tolerance induction of mature B cells in the peripheral lymphoid tissues: the blood, lymph nodes, spleen, and mucosal-associated lymphoid tissue.	tmpzr1t_l9r_go_relaxed.owl	peripheral B-cell tolerance induction|peripheral B-lymphocyte tolerance induction|peripheral B lymphocyte tolerance induction													biological_process											owl:Class	
GO:0004992	biolink:NamedThing	platelet activating factor receptor activity	Combining with platelet activating factor to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	PAF receptor activity													molecular_function											owl:Class	
GO:0044486	biolink:NamedThing	modulation of transmission of nerve impulse in other organism	The process in which an organism effects a change in the transmission of a nerve impulse in another organism.	tmpzr1t_l9r_go_relaxed.owl	modulation of conduction of nerve impulse in other organism|regulation of transmission of nerve impulse in other organism							jl	2012-01-26T04:03:31Z					biological_process											owl:Class	
GO:0061589	biolink:NamedThing	calcium activated phosphatidylserine scrambling	The movement of a population of phosphatidylserine molecules from one leaflet of the plasma membrane bilayer to the opposite leaflet as a result of a calcium stimulus.	tmpzr1t_l9r_go_relaxed.owl								dph	2014-02-05T15:17:21Z					biological_process											owl:Class	
GO:0061588	biolink:NamedThing	calcium activated phospholipid scrambling	The movement of a population of phospholipid molecules from one leaflet of the plasma membrane bilayer to the opposite leaflet as a result of a calcium stimulus.	tmpzr1t_l9r_go_relaxed.owl								dph	2014-02-05T15:14:34Z					biological_process											owl:Class	
GO:1902296	biolink:NamedThing	DNA strand elongation involved in cell cycle DNA replication	Any DNA strand elongation that is involved in cell cycle DNA replication.	tmpzr1t_l9r_go_relaxed.owl	DNA replication elongation involved in cell cycle DNA replication|DNA strand elongation during DNA replication involved in cell cycle DNA replication							jl	2013-07-10T11:47:02Z					biological_process											owl:Class	
GO:0006271	biolink:NamedThing	DNA strand elongation involved in DNA replication	The process in which an existing DNA strand is extended by activities including the addition of nucleotides to the 3' end of the strand, complementary to an existing template, as part of DNA replication.	tmpzr1t_l9r_go_relaxed.owl	DNA replication elongation|DNA strand elongation during DNA replication	https://github.com/geneontology/go-ontology/issues/12633												biological_process											owl:Class	
GO:0097053	biolink:NamedThing	L-kynurenine catabolic process	The chemical reactions and pathways resulting in the breakdown of L-kynurenine, the L-enantiomer of the amino acid kynurenine (3-(2-aminobenzoyl)-alanine).	tmpzr1t_l9r_go_relaxed.owl	L-kynurenine breakdown|L-kynurenine catabolism|L-kynurenine degradation							pr	2011-05-24T03:30:58Z					biological_process											owl:Class	
GO:0043051	biolink:NamedThing	regulation of pharyngeal pumping	Any process that modulates the contraction and relaxation movements of the pharyngeal muscle that mediates feeding in nematodes.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0018217	biolink:NamedThing	peptidyl-aspartic acid phosphorylation	The phosphorylation of peptidyl-aspartic acid.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0071597	biolink:NamedThing	cellular birth scar	Crater-like ring of chitinous scar tissue located on the surface of the daughter cell, in budding fungi, at the site of separation from the mother cell. It is formed after the newly emerged daughter cell separates, thereby marking the site of cytokinesis and septation.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-02-02T02:42:44Z					cellular_component											owl:Class	
GO:0046929	biolink:NamedThing	negative regulation of neurotransmitter secretion	Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a neurotransmitter.	tmpzr1t_l9r_go_relaxed.owl	inhibition of neurotransmitter secretion|down regulation of neurotransmitter secretion|conotoxin activity|downregulation of neurotransmitter secretion|down-regulation of neurotransmitter secretion													biological_process											owl:Class	
GO:1901665	biolink:NamedThing	negative regulation of NAD+ ADP-ribosyltransferase activity	Any process that stops, prevents or reduces the frequency, rate or extent of NAD+ ADP-ribosyltransferase activity.	tmpzr1t_l9r_go_relaxed.owl	inhibition of ADP-ribosyltransferase (polymerizing) activity|inhibition of poly(ADP-ribose) synthetase activity|downregulation of poly(ADP-ribose) synthase activity|negative regulation of poly(ADP-ribose) synthase activity|negative regulation of poly(adenosine diphosphate ribose) polymerase activity|down regulation of NAD ADP-ribosyltransferase activity|down regulation of NAD+:poly(adenine-diphosphate-D-ribosyl)-acceptor ADP-D-ribosyl-transferase activity|negative regulation of poly(ADP-ribose)polymerase activity|downregulation of poly(ADP-ribose)polymerase activity|downregulation of NAD ADP-ribosyltransferase activity|downregulation of poly(ADP-ribose) synthetase activity|negative regulation of NAD ADP-ribosyltransferase activity|inhibition of NAD+ ADP-ribosyltransferase activity|down regulation of poly(ADP-ribose) synthase activity|down regulation of ADP-ribosyltransferase (polymerizing) activity|negative regulation of ADP-ribosyltransferase (polymerizing) activity|inhibition of NAD ADP-ribosyltransferase activity|down regulation of NAD+ ADP-ribosyltransferase activity|down-regulation of NAD+:poly(adenine-diphosphate-D-ribosyl)-acceptor ADP-D-ribosyl-transferase activity|inhibition of poly(ADP-ribose)polymerase activity|downregulation of ADP-ribosyltransferase (polymerizing) activity|down regulation of poly(ADP-ribose) synthetase activity|down regulation of poly(ADP-ribose)polymerase activity|downregulation of NAD+ ADP-ribosyltransferase activity|down-regulation of NAD+ ADP-ribosyltransferase activity|down-regulation of NAD ADP-ribosyltransferase activity|negative regulation of poly(ADP-ribose) synthetase activity|inhibition of poly(adenosine diphosphate ribose) polymerase activity|down regulation of poly(adenosine diphosphate ribose) polymerase activity|inhibition of poly(ADP-ribose) synthase activity|downregulation of poly(adenosine diphosphate ribose) polymerase activity|down-regulation of poly(ADP-ribose) synthetase activity|negative regulation of NAD+:poly(adenine-diphosphate-D-ribosyl)-acceptor ADP-D-ribosyl-transferase activity|downregulation of NAD+:poly(adenine-diphosphate-D-ribosyl)-acceptor ADP-D-ribosyl-transferase activity|down-regulation of ADP-ribosyltransferase (polymerizing) activity|down-regulation of poly(ADP-ribose)polymerase activity|inhibition of NAD+:poly(adenine-diphosphate-D-ribosyl)-acceptor ADP-D-ribosyl-transferase activity|down-regulation of poly(adenosine diphosphate ribose) polymerase activity|down-regulation of poly(ADP-ribose) synthase activity							vk	2012-11-20T18:50:15Z					biological_process											owl:Class	
GO:0008907	biolink:NamedThing	integrase activity	Catalysis of the integration of one DNA segment into another.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-164523									molecular_function											owl:Class	
GO:0048081	biolink:NamedThing	positive regulation of cuticle pigmentation	Any process that activates or increases the frequency, rate or extent of establishment of a pattern of pigment in the cuticle of an organism.	tmpzr1t_l9r_go_relaxed.owl	up regulation of cuticle pigmentation|upregulation of cuticle pigmentation|up-regulation of cuticle pigmentation|activation of cuticle pigmentation|stimulation of cuticle pigmentation													biological_process											owl:Class	
GO:0098518	biolink:NamedThing	polynucleotide phosphatase activity	Catalysis of the reaction: phosphopolynucleotide + H2O = polynucleotide + phosphate.	tmpzr1t_l9r_go_relaxed.owl								dos	2013-09-26T11:02:35Z					molecular_function											owl:Class	
GO:0043414	biolink:NamedThing	macromolecule methylation	The covalent attachment of a methyl residue to one or more monomeric units in a polypeptide, polynucleotide, polysaccharide, or other biological macromolecule.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0120114	biolink:NamedThing	Sm-like protein family complex	A protein complex containing members of the Like-Sm family of proteins, which includes both the Sm proteins and the Lsm proteins, and which generally form hexameric or heptameric ring structures which bind to RNA. While some of these ring complexes may form independently of RNA, many only form in association with their target RNA. In addition to Lsm-family proteins, many of these complexes contain additional protein members. Members of this family of complexes include the snRNPs which comprise the majority of the spliceosome. Others are involved in the 5' to 3' degradation pathways of mRNAs in the cytoplasm and of unspliced transcripts in the nucleus, as well as other diverse roles.	tmpzr1t_l9r_go_relaxed.owl								krc	2017-11-06T18:46:43Z					cellular_component											owl:Class	
GO:0047457	biolink:NamedThing	exo-(1,4)-alpha-D-glucan lyase activity	Catalysis of the reaction: linear alpha-D-glucan = 1,5-anhydro-D-fructose + beta-D-glucose.	tmpzr1t_l9r_go_relaxed.owl	(1->4)-alpha-D-glucan exo-4-lyase (1,5-anhydro-D-fructose-forming)|alpha-(1->4)-glucan 1,5-anhydro-D-fructose eliminase activity|exo-(1->4)-alpha-D-glucan lyase activity|alpha-1,4-glucan exo-lyase activity|exo-alpha-1,4-glucan lyase activity|alpha-1,4-glucan 1,5-anhydro-D-fructose eliminase activity|alpha-1,4-glucan lyase activity				MetaCyc:4.2.2.13-RXN|EC:4.2.2.13									molecular_function											owl:Class	
GO:0072306	biolink:NamedThing	positive regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis	Any process that increases the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the metanephros.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of mesenchymal stem cell apoptotic process involved in metanephric nephron morphogenesis|positive regulation of mesenchymal stem cell apoptosis involved in metanephric nephron morphogenesis							mah	2010-04-09T05:03:41Z					biological_process											owl:Class	
GO:0047489	biolink:NamedThing	pectate disaccharide-lyase activity	Catalysis of the reaction: a pectate = a pectate + 4-(4-deoxy-alpha-D-galact-4-enuronosyl)-D-galacturonate. This reaction is the eliminative cleavage of 4-(4-deoxy-alpha-D-galact-4-enuronosyl)-D-galacturonate from the reducing end of pectate, i.e. de-esterified pectin.	tmpzr1t_l9r_go_relaxed.owl	PATE activity|exopectate lyase activity|Exo-PGL activity|exopectic acid transeliminase activity|exopolygalacturonate lyase activity|Exo-PATE activity|pectate exo-lyase activity|exo-PATE|exopolygalacturonic acid-trans-eliminase activity|(1->4)-alpha-D-galacturonan reducing-end-disaccharide-lyase activity|exo-PGL				EC:4.2.2.9|RHEA:57104|MetaCyc:4.2.2.9-RXN									molecular_function											owl:Class	
GO:0010846	biolink:NamedThing	activation of reciprocal meiotic recombination	Any process that starts the inactive process of reciprocal meiotic recombination. Reciprocal meiotic recombination is the cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate.	tmpzr1t_l9r_go_relaxed.owl	activation of meiotic recombination													biological_process											owl:Class	
GO:0035200	biolink:NamedThing	leg disc anterior/posterior pattern formation	The establishment, maintenance and elaboration of the anterior/posterior axis of the leg imaginal disc.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0007448	biolink:NamedThing	anterior/posterior pattern specification, imaginal disc	The establishment, maintenance and elaboration of the anterior/posterior axis of the imaginal disc. Imaginal discs are epithelial infoldings in the larvae of holometabolous insects that rapidly develop into adult appendages during metamorphosis from larval to adult form.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0072223	biolink:NamedThing	metanephric glomerular mesangium development	The process whose specific outcome is the progression of the metanephric glomerular mesangium over time, from its formation to the mature structure. The metanephric glomerular mesangium is the thin membrane connective tissue composed of mesangial cells in the metanephros, which helps to support the capillary loops in a renal glomerulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-03-18T03:35:56Z					biological_process											owl:Class	
GO:0080150	biolink:NamedThing	S-adenosyl-L-methionine:benzoic acid carboxyl methyl transferase activity	Catalysis of the reaction: benzoate + S-adenosyl-L-methionine = methylbenzoate + S-adenosyl-L-homocysteine.	tmpzr1t_l9r_go_relaxed.owl	S-adenosyl-L-methionine:benzoate carboxyl methyltransferase activity				RHEA:36099|MetaCyc:RXN-6722			dhl	2010-03-26T04:19:39Z					molecular_function											owl:Class	
GO:0043819	biolink:NamedThing	precorrin-6A synthase (deacetylating) activity	Catalysis of the reaction: S-adenosyl-L-methionine + H(2)O + precorrin-5 = S-adenosyl-L-homocysteine + acetate + 2 H(+) + precorrin-6X.	tmpzr1t_l9r_go_relaxed.owl	CobF|S-adenosyl-L-methionine:precorrin-5 C1-methyltransferase (deacetylating)|precorrin-6X synthase (deacetylating) activity				EC:2.1.1.152|RHEA:18261|MetaCyc:R322-RXN|KEGG_REACTION:R05219									molecular_function											owl:Class	
GO:0047504	biolink:NamedThing	(-)-menthol dehydrogenase activity	Catalysis of the reaction: (-)-menthol + NADP(+) = (2S,5R)-menthone + H(+) + NADPH.	tmpzr1t_l9r_go_relaxed.owl	monoterpenoid dehydrogenase activity|(-)-menthol:NADP+ oxidoreductase activity				KEGG_REACTION:R02177|EC:1.1.1.207|RHEA:13917|UM-BBD_reactionID:r1182|MetaCyc:--MENTHOL-DEHYDROGENASE-RXN									molecular_function											owl:Class	
GO:1903856	biolink:NamedThing	regulation of cytokinin dehydrogenase activity	Any process that modulates the frequency, rate or extent of cytokinin dehydrogenase activity.	tmpzr1t_l9r_go_relaxed.owl	regulation of N6-dimethylallyladenine:(acceptor) oxidoreductase activity|regulation of 6-N-dimethylallyladenine:acceptor oxidoreductase activity|regulation of cytokinin oxidase activity|regulation of N6-dimethylallyladenine:acceptor oxidoreductase activity							tb	2015-01-30T00:33:51Z					biological_process											owl:Class	
GO:1904145	biolink:NamedThing	negative regulation of meiotic cell cycle process involved in oocyte maturation	Any process that stops, prevents or reduces the frequency, rate or extent of meiotic cell cycle process involved in oocyte maturation.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of meiotic cell cycle process involved in oocyte maturation|downregulation of meiotic cell cycle process involved in oocyte maturation|inhibition of meiotic cell cycle process involved in oocyte maturation|down regulation of meiotic cell cycle process involved in oocyte maturation							tb	2015-04-14T15:59:22Z					biological_process											owl:Class	
GO:0018251	biolink:NamedThing	peptidyl-tyrosine dehydrogenation	The oxidation of the C alpha-C beta bond of peptidyl-tyrosine to form peptidyl-dehydrotyrosine coupled with cyclization of neighboring residues.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0183	See also the biological process terms 'peptide cross-linking via L-seryl-5-imidazolinone glycine ; GO:0018252' and 'peptide cross-linking via 2-imino-glutaminyl-5-imidazolinone glycine ; GO:0019729'.								biological_process											owl:Class	
GO:1905833	biolink:NamedThing	negative regulation of microtubule nucleation	Any process that stops, prevents or reduces the frequency, rate or extent of microtubule nucleation.	tmpzr1t_l9r_go_relaxed.owl	down regulation of microtubule nucleation|inhibition of microtubule nucleation|down-regulation of microtubule nucleation|downregulation of microtubule nucleation							hbye	2017-01-17T12:00:56Z					biological_process											owl:Class	
GO:0004143	biolink:NamedThing	diacylglycerol kinase activity	Catalysis of the reaction: NTP + 1,2-diacylglycerol = NDP + 1,2-diacylglycerol-3-phosphate.	tmpzr1t_l9r_go_relaxed.owl	CTP:diacylglycerol kinase activity|DGK activity|1,2-diacylglycerol kinase (phosphorylating)|DG kinase activity|ATP:1,2-diacylglycerol 3-phosphotransferase activity|sn-1,2-diacylglycerol kinase activity|ATP:diacylglycerol phosphotransferase activity|1,2-diacylglycerol kinase activity|arachidonoyl-specific diacylglycerol kinase activity|diacylglycerol:ATP kinase activity|diglyceride kinase activity				EC:2.7.1.107|Reactome:R-HSA-426240|RHEA:10272|MetaCyc:DIACYLGLYKIN-RXN									molecular_function											owl:Class	
GO:0019435	biolink:NamedThing	sophorosyloxydocosanoate biosynthetic process	The chemical reactions and pathways resulting in the formation of sophorosyloxydocosanoate, 13-sophorosyloxydocosanoate 6',6''-diacetate.	tmpzr1t_l9r_go_relaxed.owl	sophorosyloxydocosanoate anabolism|sophorosyloxydocosanoate formation|sophorosyloxydocosanoate biosynthesis|sophorosyloxydocosanoate synthesis				MetaCyc:SOPHOROSYLOXYDOCOSANOATE-SYN-PWY									biological_process											owl:Class	
GO:0019434	biolink:NamedThing	sophorosyloxydocosanoate metabolic process	The chemical reactions and pathways involving sophorosyloxydocosanoate, 13-sophorosyloxydocosanoate 6',6''-diacetate, an aromatic hydrocarbon.	tmpzr1t_l9r_go_relaxed.owl	sophorosyloxydocosanoate metabolism													biological_process											owl:Class	
GO:1904643	biolink:NamedThing	response to curcumin	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a curcumin stimulus.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-08-31T20:38:11Z					biological_process											owl:Class	
GO:2000313	biolink:NamedThing	regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation	Any process that modulates the frequency, rate or extent of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation.	tmpzr1t_l9r_go_relaxed.owl	regulation of fibroblast growth factor receptor signalling pathway involved in neural plate anterior/posterior pattern formation							vk	2011-01-18T10:26:22Z					biological_process											owl:Class	
GO:0040036	biolink:NamedThing	regulation of fibroblast growth factor receptor signaling pathway	Any process that modulates the frequency, rate or extent of fibroblast growth factor receptor signaling pathway activity.	tmpzr1t_l9r_go_relaxed.owl	regulation of FGF receptor signalling pathway|regulation of FGFR signaling pathway|regulation of FGF receptor signaling pathway													biological_process											owl:Class	
GO:0018231	biolink:NamedThing	peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine	The modification of peptidyl-cysteine to form peptidyl-S-diacylglycerol-L-cysteine; the oleate and palmitate actually represent mixtures of saturated (generally at 3') and unsaturated (generally at 2') fatty acids.	tmpzr1t_l9r_go_relaxed.owl	peptidyl-S-diacylglycerol-L-cysteine synthesis from peptidyl-cysteine|peptidyl-S-diacylglycerol-L-cysteine formation from peptidyl-cysteine|peptidyl-S-diacylglycerol-L-cysteine anabolism from peptidyl-cysteine				RESID:AA0107									biological_process											owl:Class	
GO:0035649	biolink:NamedThing	Nrd1 complex	A complex that functions in transcription termination of RNA polymerase II transcribed non-coding RNAs. This complex interacts with the carboxy-terminal domain (CTD) of PolII and the terminator sequences in the nascent RNA transcript. In yeast this complex consists of Nrd1p, Nab3p, and Sen1p.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-01-25T10:23:25Z					cellular_component											owl:Class	
GO:0004568	biolink:NamedThing	chitinase activity	Catalysis of the hydrolysis of (1->4)-beta linkages of N-acetyl-D-glucosamine (GlcNAc) polymers of chitin and chitodextrins.	tmpzr1t_l9r_go_relaxed.owl	poly[1,4-(N-acetyl-beta-D-glucosaminide)] glycanohydrolase activity|beta-1,4-poly-N-acetyl glucosamidinase activity|1,4-beta-poly-N-acetylglucosaminidase activity|chitodextrinase activity|poly-beta-glucosaminidase activity				MetaCyc:3.2.1.14-RXN|EC:3.2.1.14|Reactome:R-HSA-6786421									molecular_function											owl:Class	
GO:1905495	biolink:NamedThing	positive regulation of G-quadruplex DNA binding	Any process that activates or increases the frequency, rate or extent of G-quadruplex DNA binding.	tmpzr1t_l9r_go_relaxed.owl	up regulation of G quadruplex DNA binding|positive regulation of G quartet DNA binding|up-regulation of G quadruplex DNA binding|upregulation of G quartet DNA binding|up regulation of tetraplex DNA binding|upregulation of tetraplex DNA binding|up-regulation of G-quartet DNA binding|up regulation of quadruplex DNA binding|activation of G quadruplex DNA binding|up regulation of G-quadruplex DNA binding|activation of G-quartet DNA binding|upregulation of quadruplex DNA binding|up-regulation of quadruplex DNA binding|positive regulation of G quadruplex DNA binding|upregulation of G-DNA binding|up regulation of G quartet DNA binding|up regulation of G-DNA binding|up-regulation of tetraplex DNA binding|activation of quadruplex DNA binding|positive regulation of G-quartet DNA binding|activation of G-DNA binding|positive regulation of G-DNA binding|activation of G quartet DNA binding|positive regulation of tetraplex DNA binding|up-regulation of G-DNA binding|upregulation of G-quadruplex DNA binding|up-regulation of G-quadruplex DNA binding|activation of tetraplex DNA binding|activation of G-quadruplex DNA binding|upregulation of G-quartet DNA binding|up regulation of G-quartet DNA binding|positive regulation of quadruplex DNA binding|upregulation of G quadruplex DNA binding|up-regulation of G quartet DNA binding							ans	2016-09-26T14:53:37Z					biological_process											owl:Class	
GO:0045815	biolink:NamedThing	epigenetic maintenance of chromatin in transcription-competent conformation	An epigenetic process that capacitates gene expression by remodelling of chromatin by either modifying the chromatin fiber, the nucleosomal histones, or the DNA.	tmpzr1t_l9r_go_relaxed.owl	up regulation of gene expression, epigenetic|euchromatin organisation|maintenance of chromatin in transcription-competent conformation|euchromatin assembly|long-term maintenance of gene activation|activation of gene expression, epigenetic|chromatin-mediated maintenance of transcription|stimulation of gene expression, epigenetic|up-regulation of gene expression, epigenetic|euchromatin organization|upregulation of gene expression, epigenetic|positive regulation of gene expression, epigenetic	https://github.com/geneontology/go-ontology/issues/21730|https://github.com/geneontology/go-ontology/issues/22012				This regulation is exemplified by members of the trithorax group, which maintain the active state of homeotic gene transcription. Do not confuse with GO:0140673 ; co-transcriptional chromatin reassembly, which describes the reforming of chromatin after RNA polymerase II passage.						GO:0048096		biological_process											owl:Class	
GO:0061378	biolink:NamedThing	corpora quadrigemina development	The progression of the corpora quadrigemina over time, from its formation to the mature structure. The corpora quadrigemina is a part of the midbrain that is made up of the superior and inferior colliculi.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-11-09T09:45:36Z					biological_process											owl:Class	
GO:0042249	biolink:NamedThing	establishment of planar polarity of embryonic epithelium	Coordinated organization of groups of cells in the plane of an embryonic epithelium, such that they all orient to similar coordinates.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0008968	biolink:NamedThing	D-sedoheptulose 7-phosphate isomerase activity	Catalysis of the reaction: D-sedoheptulose-7-phosphate = D-alpha,beta-D-heptose 7-phosphate.	tmpzr1t_l9r_go_relaxed.owl	phosphoheptose isomerase activity				MetaCyc:RXN0-4301|RHEA:27489									molecular_function											owl:Class	
GO:0060711	biolink:NamedThing	labyrinthine layer development	The process in which the labyrinthine layer of the placenta progresses, from its formation to its mature state.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-06-09T03:27:43Z					biological_process											owl:Class	
GO:1990315	biolink:NamedThing	Mcs4 RR-MAPKKK complex	A protein complex that consists of a phospho relay component and a MAPK cascade component.  The complex is involved in signaling oxidative stress and osmostress.	tmpzr1t_l9r_go_relaxed.owl						In S. pombe it consists of Mpr1, Tdh1, Mcs4, Win1, Wis4 and Wis1.		al	2014-03-14T09:59:45Z					cellular_component											owl:Class	
GO:0120186	biolink:NamedThing	negative regulation of protein localization to chromatin	Any process that stops, prevents, or reduces the frequency, rate or extent of protein localization to chromatin.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of protein localisation to chromatin							krc	2018-07-14T00:19:32Z					biological_process											owl:Class	
GO:1905634	biolink:NamedThing	regulation of protein localization to chromatin	Any process that modulates the frequency, rate or extent of protein localization to chromatin.	tmpzr1t_l9r_go_relaxed.owl	regulation of protein localisation to chromatin							pga	2016-11-01T16:33:52Z					biological_process											owl:Class	
GO:0046511	biolink:NamedThing	sphinganine biosynthetic process	The chemical reactions and pathways resulting in the formation of sphinganine, D-erythro-2-amino-1,3-octadecanediol.	tmpzr1t_l9r_go_relaxed.owl	dihydrosphingosine biosynthetic process|dihydrosphingosine biosynthesis|sphinganine biosynthesis|sphinganine formation|sphinganine synthesis|sphinganine anabolism													biological_process											owl:Class	
GO:0034312	biolink:NamedThing	diol biosynthetic process	The chemical reactions and pathways resulting in the formation of a diol, any alcohol containing two hydroxyl groups attached to saturated carbon atoms.	tmpzr1t_l9r_go_relaxed.owl	dihydric alcohol biosynthetic process|diol anabolism|diol synthesis|diol formation|diol biosynthesis													biological_process											owl:Class	
GO:0019731	biolink:NamedThing	antibacterial humoral response	An immune response against bacteria mediated through a body fluid. Examples of this process are the antibacterial humoral responses in Mus musculus and Drosophila melanogaster.	tmpzr1t_l9r_go_relaxed.owl												GO:0006961|GO:0019733		biological_process											owl:Class	
GO:0010457	biolink:NamedThing	centriole-centriole cohesion	The cell cycle process in which the two centrioles within a centrosome remain tightly paired.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0010829	biolink:NamedThing	negative regulation of glucose transmembrane transport	Any process that decreases the frequency, rate or extent of glucose transport across a membrane. Glucose transport is the directed movement of the hexose monosaccharide glucose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of glucose transport													biological_process											owl:Class	
GO:0080164	biolink:NamedThing	regulation of nitric oxide metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nitric oxide, nitrogen monoxide (NO), a colorless gas only slightly soluble in water.	tmpzr1t_l9r_go_relaxed.owl								dhl	2010-09-23T04:02:50Z					biological_process											owl:Class	
GO:0120292	biolink:NamedThing	positive regulation of mitotic recombination-dependent replication fork processing	Any process that activates or increases the frequency, rate or extent of replication fork processing that includes recombination between DNA near the arrested fork and homologous sequences. Proteins involved in homologous recombination are required for replication restart.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of homologous recombination-dependent replication fork processing|positive regulation of homologous recombination dependent replication fork recovery|positive regulation of recombination-dependent DNA replication							krc	2021-01-06T19:09:21Z					biological_process											owl:Class	
GO:0019786	biolink:NamedThing	Atg8-specific protease activity	Catalysis of the hydrolysis of APG8, a small ubiquitin-related modifier.	tmpzr1t_l9r_go_relaxed.owl	APG8-PE hydrolase|APG8-specific protease activity													molecular_function											owl:Class	
GO:0043626	biolink:NamedThing	PCNA complex	A protein complex composed of three identical PCNA monomers, each comprising two similar domains, which are joined in a head-to-tail arrangement to form a homotrimer. Forms a ring-like structure in solution, with a central hole sufficiently large to accommodate the double helix of DNA. Originally characterized as a DNA sliding clamp for replicative DNA polymerases and as an essential component of the replisome, and has also been shown to be involved in other processes including Okazaki fragment processing, DNA repair, translesion DNA synthesis, DNA methylation, chromatin remodeling and cell cycle regulation.	tmpzr1t_l9r_go_relaxed.owl	proliferating cell nuclear antigen complex|PCNA homotrimer|sliding clamp													cellular_component											owl:Class	
GO:0003362	biolink:NamedThing	noradrenergic neuron fate commitment involved in brainstem development	The process in which the developmental fate of a cell becomes restricted such that it will develop into a noradrenergic neuron that is part of the brainstem.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-12-03T10:56:16Z					biological_process											owl:Class	
GO:0003359	biolink:NamedThing	noradrenergic neuron fate commitment	The process in which the developmental fate of a cell becomes restricted such that it will develop into a noradrenergic neuron.	tmpzr1t_l9r_go_relaxed.owl	norepinephrine secreting neuron fate commitment							dph	2009-12-03T10:41:08Z					biological_process											owl:Class	
GO:0009939	biolink:NamedThing	positive regulation of gibberellic acid mediated signaling pathway	Any process that activates or increases the frequency, rate or extent of gibberellic acid mediated signaling activity.	tmpzr1t_l9r_go_relaxed.owl	stimulation of gibberellic acid mediated signaling|activation of gibberellic acid mediated signaling|upregulation of gibberellic acid mediated signaling|up regulation of gibberellic acid mediated signaling|positive regulation of gibberellic acid mediated signalling|up-regulation of gibberellic acid mediated signaling													biological_process											owl:Class	
GO:0047568	biolink:NamedThing	3-oxo-5-beta-steroid 4-dehydrogenase activity	Catalysis of the reaction: a 3-oxo-5-beta-steroid + acceptor = a 3-oxo-D4-steroid + reduced acceptor.	tmpzr1t_l9r_go_relaxed.owl	3-oxo-5beta-steroid 4-dehydrogenase activity|delta4-3-ketosteroid 5-beta-reductase activity|3-oxo-5beta-steroid:acceptor delta4-oxidoreductase activity|3-oxo-5beta-steroid:(acceptor) delta4-oxidoreductase activity				RHEA:24172|MetaCyc:3-OXO-5-BETA-STEROID-4-DEHYDROGENASE-RXN|EC:1.3.99.6									molecular_function											owl:Class	
GO:0002241	biolink:NamedThing	response to parasitic plant	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a parasitic plant.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0102766	biolink:NamedThing	naringenin 7-O-methyltransferase activity	Catalysis of the reaction: (S)-naringenin(1-) + S-adenosyl-L-methionine  <=> sakuranetin + S-adenosyl-L-homocysteine  + H+.	tmpzr1t_l9r_go_relaxed.owl					RHEA:31539|EC:2.1.1.232|MetaCyc:RXN-7773									molecular_function											owl:Class	
GO:0062200	biolink:NamedThing	RAM/MOR signaling pathway	An intracellular signaling pathway that regulates interphase polarized growth and cell separation at the end of cytokinesis through activation of the NDR1/2-related kinase.	tmpzr1t_l9r_go_relaxed.owl	RAM signaling pathway|MOR signaling pathway|morphogenesis Orb6 network							dph	2019-12-17T20:21:12Z					biological_process											owl:Class	
GO:0015671	biolink:NamedThing	oxygen transport	The directed movement of oxygen (O2) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0015669	biolink:NamedThing	gas transport	The directed movement of substances that are gaseous in normal living conditions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0061896	biolink:NamedThing	all-trans retinol 3,4-desaturase activity	Catalysis of the reaction: all-trans-retinol + 2 H(+) + O2 + 2 reduced [adrenodoxin] = all-trans-3,4-didehydro retinol + 2 H2O + 2 oxidized [adrenodoxin].	tmpzr1t_l9r_go_relaxed.owl					RHEA:50292			dph	2017-06-12T14:49:30Z					molecular_function											owl:Class	
GO:2000672	biolink:NamedThing	negative regulation of motor neuron apoptotic process	Any process that stops, prevents or reduces the frequency, rate or extent of motor neuron apoptotic process.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of motoneuron apoptosis|negative regulation of motor neuron apoptosis							pr	2011-05-09T10:56:21Z					biological_process											owl:Class	
GO:0035538	biolink:NamedThing	carbohydrate response element binding	Binding to a carbohydrate response element (ChoRE) found in the promoters of genes whose expression is regulated in response to carbohydrates, such as the triglyceride synthesis genes.	tmpzr1t_l9r_go_relaxed.owl	ChoRE binding					Note that as agreed during the transcription overhaul, terms specifying binding to specific transcription regulatory motifs are no longer being created. The level of specificity GO has decided to go to is the "core promoter", "core promoter proximal region" and "enhancer". To capture more detail, please consider using column 16.		bf	2010-05-07T10:48:30Z					molecular_function											owl:Class	
GO:2001077	biolink:NamedThing	(1->3),(1->4)-beta-glucan binding	Binding to (1->3),(1->4)-beta-glucan.	tmpzr1t_l9r_go_relaxed.owl	beta-(1,3),(1,4)-glucan binding|beta-(1->3),(1->4)-glucan binding|beta-1,3-1,4-glucan binding|beta-1->3,1->4-glucan binding|1->3,1->4-beta-glucan binding|(1,3),(1,4)-beta-glucan binding							jl	2011-09-15T09:07:33Z					molecular_function											owl:Class	
GO:2000603	biolink:NamedThing	regulation of secondary growth	Any process that modulates the frequency, rate or extent of secondary growth.	tmpzr1t_l9r_go_relaxed.owl								tb	2011-04-15T10:30:44Z					biological_process											owl:Class	
GO:0034354	biolink:NamedThing	'de novo' NAD biosynthetic process from tryptophan	The chemical reactions and pathways resulting in the formation of nicotinamide adenine dinucleotide (NAD), beginning with the synthesis of tryptophan from simpler precursors; biosynthesis may be of either the oxidized form, NAD, or the reduced form, NADH.	tmpzr1t_l9r_go_relaxed.owl	de novo NAD biosynthetic process from tryptophan													biological_process											owl:Class	
GO:0070041	biolink:NamedThing	rRNA (uridine-C5-)-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing C5-methyluridine.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0047689	biolink:NamedThing	aspartate racemase activity	Catalysis of the reaction: L-aspartate = D-aspartate.	tmpzr1t_l9r_go_relaxed.owl	D-aspartate racemase activity				RHEA:14973|EC:5.1.1.13|MetaCyc:ASPARTATE-RACEMASE-RXN|KEGG_REACTION:R00491									molecular_function											owl:Class	
GO:1904690	biolink:NamedThing	positive regulation of cytoplasmic translational initiation	Any process that activates or increases the frequency, rate or extent of cytoplasmic translational initiation.	tmpzr1t_l9r_go_relaxed.owl	up regulation of cytoplasmic translational initiation|upregulation of cytoplasmic translational initiation|activation of cytoplasmic translational initiation|up-regulation of cytoplasmic translational initiation							dos	2015-09-25T14:39:50Z					biological_process											owl:Class	
GO:0031009	biolink:NamedThing	plastid ADPG pyrophosphorylase complex	An ADPG pyrophosphorylase complex found in a plastid.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0034911	biolink:NamedThing	phthalate 3,4-dioxygenase activity	Catalysis of the reaction: phthalate + O2 + NADH + H+ = phthalate 3,4-cis-dihydrodiol + NAD+.	tmpzr1t_l9r_go_relaxed.owl					EC:1.14.12.-|UM-BBD_reactionID:r1444									molecular_function											owl:Class	
GO:0033440	biolink:NamedThing	ACG codon-amino acid adaptor activity	A triplet codon-amino acid adaptor activity that recognizes an ACG codon.	tmpzr1t_l9r_go_relaxed.owl	threonine tRNA					Note that in the standard genetic code, ACG codes for threonine.								molecular_function											owl:Class	
GO:0032261	biolink:NamedThing	purine nucleotide salvage	Any process which produces a purine nucleotide from derivatives of it, without de novo synthesis.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0008759	biolink:NamedThing	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity	Catalysis of the removal of an acetyl group from the 2-N position of glucosamine in the lipid A precursor UDP-3-O-(R-3-hydroxymyristoyl)-N-acetylglucosamine.	tmpzr1t_l9r_go_relaxed.owl					EC:3.5.1.108									molecular_function											owl:Class	
GO:1900169	biolink:NamedThing	regulation of glucocorticoid mediated signaling pathway	Any process that modulates the frequency, rate or extent of glucocorticoid mediated signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	regulation of glucocorticoid mediated signalling							hjd	2012-03-08T08:33:16Z					biological_process											owl:Class	
GO:0099170	biolink:NamedThing	postsynaptic modulation of chemical synaptic transmission	Any process, acting in the postsynapse that results in modulation of chemical synaptic transmission.	tmpzr1t_l9r_go_relaxed.owl								dos	2017-09-11T17:09:17Z					biological_process											owl:Class	
GO:0090556	biolink:NamedThing	phosphatidylserine floppase activity	Catalysis of the movement of phosphatidylserine from the cytosolic to the exoplasmic leaftlet of a membrane, using energy from the hydrolysis of ATP.	tmpzr1t_l9r_go_relaxed.owl	ATPase-dependent phosphatidylserine transporter activity|ATPase-coupled phosphatidylserine transporter activity|phosphatidylserine floppase activity (cytosolic to exoplasmic leaftlet)|phosphatidylserine-translocating ATPase activity				RHEA:38567			tb	2013-10-24T16:07:20Z					molecular_function											owl:Class	
GO:1905789	biolink:NamedThing	positive regulation of detection of mechanical stimulus involved in sensory perception of touch	Any process that activates or increases the frequency, rate or extent of detection of mechanical stimulus involved in sensory perception of touch.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of perception of touch, sensory transduction of mechanical stimulus|activation of detection of mechanical stimulus involved in sensory perception of touch|positive regulation of perception of touch, detection of mechanical stimulus|upregulation of tactition, sensory detection of mechanical stimulus|up regulation of sensory detection of mechanical stimulus during perception of touch|up regulation of perception of touch, detection of mechanical stimulus|positive regulation of perception of touch, sensory transduction of mechanical stimulus|up-regulation of perception of touch, detection of mechanical stimulus|up regulation of perception of touch, sensory transduction of mechanical stimulus|up regulation of detection of mechanical stimulus involved in sensory perception of touch|upregulation of perception of touch, sensory detection of mechanical stimulus|positive regulation of perception of touch, sensory detection of mechanical stimulus|positive regulation of sensory transduction of mechanical stimulus during perception of touch|up regulation of perception of touch, sensory detection of mechanical stimulus|up regulation of tactition, sensory detection of mechanical stimulus|up-regulation of tactition, sensory detection of mechanical stimulus|up-regulation of perception of touch, sensory detection of mechanical stimulus|activation of tactition, sensory detection of mechanical stimulus|activation of perception of touch, sensory detection of mechanical stimulus|activation of perception of touch, sensory transduction of mechanical stimulus|upregulation of perception of touch, sensory transduction of mechanical stimulus|activation of sensory detection of mechanical stimulus during perception of touch|up-regulation of detection of mechanical stimulus involved in sensory perception of touch|up-regulation of sensory detection of mechanical stimulus during perception of touch|upregulation of detection of mechanical stimulus involved in sensory perception of touch|up regulation of sensory transduction of mechanical stimulus during perception of touch|activation of sensory transduction of mechanical stimulus during perception of touch|upregulation of sensory transduction of mechanical stimulus during perception of touch|activation of perception of touch, detection of mechanical stimulus|positive regulation of tactition, sensory detection of mechanical stimulus|up-regulation of sensory transduction of mechanical stimulus during perception of touch|positive regulation of sensory detection of mechanical stimulus during perception of touch|upregulation of sensory detection of mechanical stimulus during perception of touch|upregulation of perception of touch, detection of mechanical stimulus							hbye	2017-01-09T15:11:23Z					biological_process											owl:Class	
GO:1990709	biolink:NamedThing	presynaptic active zone organization	A process that results in the assembly, arrangement of constituent parts, or disassembly of a presynaptic active zone.	tmpzr1t_l9r_go_relaxed.owl	presynaptic active zone organisation							pr	2015-03-20T10:16:24Z					biological_process											owl:Class	
GO:2000852	biolink:NamedThing	regulation of corticosterone secretion	Any process that modulates the frequency, rate or extent of corticosterone secretion.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-07-26T08:45:40Z					biological_process											owl:Class	
GO:1903919	biolink:NamedThing	negative regulation of actin filament severing	Any process that stops, prevents or reduces the frequency, rate or extent of actin filament severing.	tmpzr1t_l9r_go_relaxed.owl	downregulation of F-actin severing|negative regulation of barbed-end actin capping/severing activity|inhibition of actin filament severing activity|down-regulation of barbed-end actin capping/severing activity|down-regulation of F-actin severing|down regulation of actin filament severing activity|inhibition of actin filament severing|negative regulation of actin filament severing activity|negative regulation of F-actin severing|down regulation of F-actin severing|downregulation of barbed-end actin capping/severing activity|inhibition of F-actin severing|down-regulation of actin filament severing|downregulation of actin filament severing activity|down-regulation of actin filament severing activity|downregulation of actin filament severing|inhibition of barbed-end actin capping/severing activity|down regulation of barbed-end actin capping/severing activity|down regulation of actin filament severing							als	2015-02-10T11:01:31Z					biological_process											owl:Class	
GO:1903918	biolink:NamedThing	regulation of actin filament severing	Any process that modulates the frequency, rate or extent of actin filament severing.	tmpzr1t_l9r_go_relaxed.owl	regulation of actin filament severing activity|regulation of F-actin severing|regulation of barbed-end actin capping/severing activity							als	2015-02-10T11:01:21Z					biological_process											owl:Class	
GO:0003394	biolink:NamedThing	cell adhesion involved in dendrite retrograde extension	The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix that contributes to the process of retrograde extension of a dendrite.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-12-09T09:42:09Z					biological_process											owl:Class	
GO:0007155	biolink:NamedThing	cell adhesion	The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules.	tmpzr1t_l9r_go_relaxed.owl	single organism cell adhesion|cell adhesion molecule activity				Wikipedia:Cell_adhesion			dos	2014-04-15T15:59:10Z			GO:0098602		biological_process											owl:Class	
GO:1990059	biolink:NamedThing	fruit valve development	The process whose specific outcome is the progression of the fruit valve over time, from its formation to the mature structure. The fruit valve is a part of a fruit that splits apart when the fruit dehisces.	tmpzr1t_l9r_go_relaxed.owl								dhl	2013-03-12T21:21:15Z					biological_process											owl:Class	
GO:0061807	biolink:NamedThing	positive regulation of DNA recombination at centromere	Any process that activates or increases the frequency, rate or extent of DNA recombination at the centromere.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of centromeric recombination							dph	2016-11-10T15:20:04Z					biological_process											owl:Class	
GO:0045911	biolink:NamedThing	positive regulation of DNA recombination	Any process that activates or increases the frequency, rate or extent of DNA recombination.	tmpzr1t_l9r_go_relaxed.owl	activation of DNA recombination|upregulation of DNA recombination|up-regulation of DNA recombination|up regulation of DNA recombination|stimulation of DNA recombination													biological_process											owl:Class	
GO:0022019	biolink:NamedThing	dorsal lateral ganglionic eminence cell proliferation	The multiplication or reproduction of dorsal lateral ganglionic eminence cells, resulting in the expansion of the cell population.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0061522	biolink:NamedThing	1,4-dihydroxy-2-naphthoyl-CoA thioesterase activity	Catalysis of the reaction 1,4-dihydroxy-2-naphthoyl-CoA + H2O = 1,4-dihydroxy-2-naphthoate + CoA.	tmpzr1t_l9r_go_relaxed.owl								dph	2013-04-18T14:37:32Z					molecular_function											owl:Class	
GO:1990938	biolink:NamedThing	peptidyl-aspartic acid autophosphorylation	The phosphorylation by a protein of one or more of its own aspartate amino acid residues, or an aspartate residue on an identical protein.	tmpzr1t_l9r_go_relaxed.owl	peptidyl-aspartate autophosphorylation|aspartyl autophosphorylation							bf	2016-04-04T10:49:53Z					biological_process											owl:Class	
GO:1905796	biolink:NamedThing	regulation of intraciliary anterograde transport	Any process that modulates the frequency, rate or extent of intraciliary anterograde transport.	tmpzr1t_l9r_go_relaxed.owl	regulation of intraflagellar anterograde transport							hbye	2017-01-11T12:55:35Z					biological_process											owl:Class	
GO:0097507	biolink:NamedThing	hypoxanthine DNA N-glycosylase activity	DNA N-glycosylase activity acting on deaminated adenine (hypoxanthine).	tmpzr1t_l9r_go_relaxed.owl	hypoxanthine-DNA glycosylase activity							pr	2013-09-26T16:02:08Z					molecular_function											owl:Class	
GO:0110146	biolink:NamedThing	magnetosome membrane	The lipid bilayer surrounding a magnetosome.	tmpzr1t_l9r_go_relaxed.owl								kmv	2019-05-30T17:51:09Z					cellular_component											owl:Class	
GO:0043236	biolink:NamedThing	laminin binding	Binding to a laminin, a major glycoprotein constituent of the basement membrane of cells.	tmpzr1t_l9r_go_relaxed.owl	laminin-4 binding|laminin-2 binding											GO:0043238|GO:0043239		molecular_function											owl:Class	
GO:0042812	biolink:NamedThing	pheromone catabolic process	The chemical reactions and pathways resulting in the breakdown of pheromones, a substance that is secreted and released by an organism and detected by a second organism of the same or a closely related species, in which it causes a specific reaction, such as a definite behavioral reaction or a developmental process.	tmpzr1t_l9r_go_relaxed.owl	pheromone degradation|pheromone catabolism|pheromone breakdown											GO:0046614|GO:0007327		biological_process											owl:Class	
GO:0021841	biolink:NamedThing	chemoattraction involved in interneuron migration from the subpallium to the cortex	The creation and reception of signals that result in the movement of interneurons toward the signal, where this process is involved in migration from the subpallium to the cortex.	tmpzr1t_l9r_go_relaxed.owl	positive chemotaxis involved in interneuron migration from the subpallium to the cortex													biological_process											owl:Class	
GO:0016081	biolink:NamedThing	synaptic vesicle docking	The initial (indirect) attachment of a synaptic vesicle membrane to the presynaptic active zone membrane, mediated by proteins protruding from the membrane and proteins of the presynaptic active zone cytoplasmic component.  Synaptic vesicle tethering is the first step in this process.	tmpzr1t_l9r_go_relaxed.owl	synaptic vesicle docking involved in exocytosis|synaptic vesicle docking during exocytosis					Although this process can occur outside of synaptic transmission, by convention we treat it as a part of synaptic transmission (dos, pvn, fk synapse project 2015).								biological_process											owl:Class	
GO:0006904	biolink:NamedThing	vesicle docking involved in exocytosis	The initial attachment of a vesicle membrane to a target membrane, mediated by proteins protruding from the membrane of the vesicle and the target membrane, that contributes to exocytosis.	tmpzr1t_l9r_go_relaxed.owl	vesicle docking during exocytosis													biological_process											owl:Class	
GO:0072130	biolink:NamedThing	renal capsule specification	The regionalization process in which the identity of the renal capsule is specified. Identity is considered to be the aggregate of characteristics by which a structure is recognized.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-02-22T02:12:34Z					biological_process											owl:Class	
GO:0097029	biolink:NamedThing	mature conventional dendritic cell differentiation	The process in which antigen-activated dendritic cells acquire the specialized features of a mature conventional dendritic cell. Mature conventional dendritic cells upregulate the surface expression of MHC molecules, chemokine receptors and adhesion molecules, and increase the number of dendrites (cytoplasmic protrusions) in preparation for migration to lymphoid organs where they present antigen to T cells.	tmpzr1t_l9r_go_relaxed.owl						Note that immunologists typically use the word 'maturation' to refer to dendritic cells undergoing the process that GO describes as 'cell differentiation'.		pr	2011-04-01T10:10:22Z					biological_process											owl:Class	
GO:0046098	biolink:NamedThing	guanine metabolic process	The chemical reactions and pathways involving guanine, 2-amino-6-hydroxypurine, a purine that is one of the five main bases found in nucleic acids and a component of a number of phosphorylated guanosine derivatives whose metabolic or regulatory functions are important.	tmpzr1t_l9r_go_relaxed.owl	guanine metabolism													biological_process											owl:Class	
GO:0140635	biolink:NamedThing	neutrophil dispersal	The movement of a neutrophil away from the site of wound or infection following its initial migration to the site.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/21081						pg	2021-04-13T07:06:25Z					biological_process											owl:Class	
GO:0050155	biolink:NamedThing	ornithine(lysine) transaminase activity	Catalysis of the reaction: 2-oxoglutarate + L-ornithine = H2O + L-glutamate + 3,4-dihydro-2H-pyrrole-2-carboxylate.	tmpzr1t_l9r_go_relaxed.owl	lysine/ornithine:2-oxoglutarate aminotransferase activity|ornithine(lysine) aminotransferase activity|L-ornithine:2-oxoglutarate-aminotransferase activity|L-ornithine(L-lysine):2-oxoglutarate-aminotransferase activity				EC:2.6.1.13|MetaCyc:ORNITHINELYSINE-AMINOTRANSFERASE-RXN									molecular_function											owl:Class	
GO:0010630	biolink:NamedThing	regulation of transcription, start site selection	Any process that modulates the frequency, rate or extent of the synthesis of either RNA on a template of DNA or DNA on a template of RNA by a mechanism that selects the start site along that template.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0048767	biolink:NamedThing	root hair elongation	The process in which the root hair grows longer.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1901943	biolink:NamedThing	(+)-epi-alpha-bisabolol biosynthetic process	The chemical reactions and pathways resulting in the formation of (+)-epi-alpha-bisabolol.	tmpzr1t_l9r_go_relaxed.owl	(+)-epi-alpha-bisabolol synthesis|(+)-epi-alpha-bisabolol biosynthesis|(+)-epi-alpha-bisabolol anabolism|(+)-epi-alpha-bisabolol formation							ms	2013-02-18T14:55:46Z					biological_process											owl:Class	
GO:0033910	biolink:NamedThing	glucan 1,4-alpha-maltotetraohydrolase activity	Catalysis of the hydrolysis of (1->4)-alpha-D-glucosidic linkages in amylaceous polysaccharides, to remove successive maltotetraose residues from the non-reducing chain ends.	tmpzr1t_l9r_go_relaxed.owl	glucan 1,4-alpha-maltotetrahydrolase activity|G4-amylase activity|maltotetraose-forming amylase activity|1,4-alpha-D-glucan maltotetraohydrolase activity|exo-maltotetraohydrolase activity				EC:3.2.1.60|MetaCyc:3.2.1.60-RXN									molecular_function											owl:Class	
GO:0047828	biolink:NamedThing	D-lyxose ketol-isomerase activity	Catalysis of the reaction: D-lyxose = D-xylulose.	tmpzr1t_l9r_go_relaxed.owl	D-lyxose isomerase activity|D-lyxose aldose-ketose-isomerase activity				RHEA:14201|KEGG_REACTION:R01898|MetaCyc:D-LYXOSE-KETOL-ISOMERASE-RXN|EC:5.3.1.15									molecular_function											owl:Class	
GO:0042960	biolink:NamedThing	antimonite secondary active transmembrane transporter activity	Enables the transfer of antimonite from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters.	tmpzr1t_l9r_go_relaxed.owl	antimonite porter activity													molecular_function											owl:Class	
GO:0034607	biolink:NamedThing	turning behavior involved in mating	The sharp ventral turn performed by the male as he approaches either the hermaphrodite head or tail, whilst trying to locate his partner's vulva. Turning occurs via a sharp ventral coil of the male's tail.	tmpzr1t_l9r_go_relaxed.owl	turning behavior during mating													biological_process											owl:Class	
GO:0061974	biolink:NamedThing	perichondral bone morphogenesis	The process in which bones are generated and organized as a result of the conversion of initial connective tissue surrounding cartilage into bone.	tmpzr1t_l9r_go_relaxed.owl								dph	2018-02-12T18:26:10Z					biological_process											owl:Class	
GO:1904604	biolink:NamedThing	negative regulation of advanced glycation end-product receptor activity	Any process that stops, prevents or reduces the frequency, rate or extent of advanced glycation end-product receptor activity.	tmpzr1t_l9r_go_relaxed.owl	inhibition of advanced glycation end-product receptor activity|downregulation of RAGE activity|down regulation of AGE receptor activity|down-regulation of AGE receptor activity|down regulation of advanced glycation end-product receptor activity|inhibition of AGE receptor activity|down-regulation of RAGE activity|downregulation of AGE receptor activity|down-regulation of advanced glycation end-product receptor activity|negative regulation of RAGE activity|negative regulation of AGE receptor activity|down regulation of RAGE activity|inhibition of RAGE activity|downregulation of advanced glycation end-product receptor activity							krc	2015-08-26T16:24:56Z					biological_process											owl:Class	
GO:1905290	biolink:NamedThing	negative regulation of CAMKK-AMPK signaling cascade	Any process that stops, prevents or reduces the frequency, rate or extent of CAMKK-AMPK signaling cascade.	tmpzr1t_l9r_go_relaxed.owl	down regulation of CAMKK-AMPK signaling cascade|downregulation of CAMKK-AMPK signaling cascade|negative regulation of stress-activated AMP-activated protein kinase signaling cascade|inhibition of stress-activated AMP-activated protein kinase signaling cascade|down-regulation of CAMKK-AMPK signaling cascade|down regulation of stress-activated AMP-activated protein kinase signaling cascade|down-regulation of stress-activated AMP-activated protein kinase signaling cascade|inhibition of CAMKK-AMPK signaling cascade|downregulation of stress-activated AMP-activated protein kinase signaling cascade							sl	2016-06-23T20:37:03Z					biological_process											owl:Class	
GO:0036387	biolink:NamedThing	pre-replicative complex	A protein-DNA complex that forms at the origin of replication during the initial step of DNA replication and allows the origin to become competent, or 'licensed', for replication.	tmpzr1t_l9r_go_relaxed.owl	pre-RC|pre-replication complex					This term describes pre-replicative complexes across organisms.		bf	2013-06-05T16:14:52Z					cellular_component											owl:Class	
GO:1905394	biolink:NamedThing	retromer complex binding	Binding to a retromer complex.	tmpzr1t_l9r_go_relaxed.owl								bc	2016-08-24T14:00:32Z					molecular_function											owl:Class	
GO:0005594	biolink:NamedThing	collagen type IX trimer	A collagen heterotrimer containing type IX alpha chains in alpha1(IX)alpha2(IX)alpha3(IX) trimers; type IX collagen triple helices associate to form a structure that links glycosaminoglycans to type II collagen fibrils.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0002049	biolink:NamedThing	pyoverdine biosynthetic process	The chemical reactions and pathways resulting in the formation of the siderochrome pyoverdine.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1901180	biolink:NamedThing	spheroidene biosynthetic process	The chemical reactions and pathways resulting in the formation of spheroidene.	tmpzr1t_l9r_go_relaxed.owl	spheroidene synthesis|spheroidene biosynthesis|spheroidene formation|spheroidene anabolism							yaf	2012-07-19T09:49:22Z					biological_process											owl:Class	
GO:0043067	biolink:NamedThing	regulation of programmed cell death	Any process that modulates the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes.	tmpzr1t_l9r_go_relaxed.owl	regulation of non-apoptotic programmed cell death											GO:0043070		biological_process											owl:Class	
GO:1990648	biolink:NamedThing	inositol-4,5,6-triphosphate 5-phosphatase activity	Catalysis of the reaction: 1D-myo-inositol 4,5,6-trisphosphate + H2O = 1D-myo-inositol 4,6-bisphosphate + phosphate.	tmpzr1t_l9r_go_relaxed.owl								al	2015-02-23T11:10:51Z					molecular_function											owl:Class	
GO:0046030	biolink:NamedThing	inositol trisphosphate phosphatase activity	Catalysis of the reaction: myo-inositol trisphosphate + H2O = myo-inositol bisphosphate + phosphate.	tmpzr1t_l9r_go_relaxed.owl	IP(3) phosphatase activity|IP3 phosphatase activity|inositol-1,4,5-trisphosphate phosphatase													molecular_function											owl:Class	
GO:1900964	biolink:NamedThing	positive regulation of methanophenazine biosynthetic process	Any process that activates or increases the frequency, rate or extent of methanophenazine biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of methanophenazine formation|upregulation of methanophenazine anabolism|activation of methanophenazine anabolism|up regulation of methanophenazine synthesis|activation of methanophenazine synthesis|positive regulation of methanophenazine synthesis|up-regulation of methanophenazine formation|upregulation of methanophenazine biosynthetic process|up-regulation of methanophenazine anabolism|upregulation of methanophenazine synthesis|activation of methanophenazine biosynthetic process|up-regulation of methanophenazine biosynthesis|upregulation of methanophenazine formation|positive regulation of methanophenazine biosynthesis|activation of methanophenazine biosynthesis|up regulation of methanophenazine biosynthetic process|up-regulation of methanophenazine biosynthetic process|up regulation of methanophenazine biosynthesis|upregulation of methanophenazine biosynthesis|activation of methanophenazine formation|up regulation of methanophenazine formation|positive regulation of methanophenazine anabolism|up regulation of methanophenazine anabolism|up-regulation of methanophenazine synthesis							tt	2012-06-14T03:53:46Z					biological_process											owl:Class	
GO:0018747	biolink:NamedThing	phenanthrene-1,2-epoxide hydrolase activity	Catalysis of the reaction: phenanthrene-1,2-oxide + H2O = trans-1,2-dihydrodiolphenanthrene.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0536									molecular_function											owl:Class	
GO:0042583	biolink:NamedThing	chromaffin granule	Specialized secretory vesicle found in the cells of adrenal glands and various other organs, which is concerned with the synthesis, storage, metabolism, and secretion of epinephrine and norepinephrine.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0004073	biolink:NamedThing	aspartate-semialdehyde dehydrogenase activity	Catalysis of the reaction: L-aspartate 4-semialdehyde + NADP(+) + phosphate = 4-phospho-L-aspartate + H(+) + NADPH.	tmpzr1t_l9r_go_relaxed.owl	aspartate semialdehyde dehydrogenase activity|ASA dehydrogenase activity|aspartic semialdehyde dehydrogenase activity|L-aspartate-beta-semialdehyde:NADP oxidoreductase (phosporylating)|aspartic beta-semialdehyde dehydrogenase activity|L-aspartate-beta-semialdehyde dehydrogenase activity|L-aspartate-4-semialdehyde:NADP+ oxidoreductase (phosphorylating)				EC:1.2.1.11|MetaCyc:ASPARTATE-SEMIALDEHYDE-DEHYDROGENASE-RXN|KEGG_REACTION:R02291|RHEA:24284									molecular_function											owl:Class	
GO:0001879	biolink:NamedThing	detection of yeast	The series of events in which a stimulus from a yeast is received and converted into a molecular signal.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0001878	biolink:NamedThing	response to yeast	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a yeast species.	tmpzr1t_l9r_go_relaxed.owl						defined as response to Saccharomycotina (true yeasts). This excludes fission yeast.								biological_process											owl:Class	
GO:0034094	biolink:NamedThing	regulation of maintenance of meiotic sister chromatid cohesion	Any process that modulates the extent to which the association between sister chromatids of a replicated chromosome is maintained during a meiotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1901299	biolink:NamedThing	negative regulation of hydrogen peroxide-mediated programmed cell death	Any process that stops, prevents or reduces the frequency, rate or extent of hydrogen peroxide-mediated programmed cell death.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of hydrogen peroxide-mediated programmed cell death|down regulation of hydrogen peroxide-mediated programmed cell death|downregulation of hydrogen peroxide-mediated programmed cell death|inhibition of hydrogen peroxide-mediated programmed cell death							vk	2012-08-21T09:45:21Z					biological_process											owl:Class	
GO:0034876	biolink:NamedThing	isonicotinic acid hydrazide hydrolase activity	Catalysis of the reaction: isoniazid + H2O = isonicotinate + hydrazine.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r1336									molecular_function											owl:Class	
GO:1900284	biolink:NamedThing	positive regulation of cellobiose catabolic process	Any process that activates or increases the frequency, rate or extent of cellobiose catabolic process.	tmpzr1t_l9r_go_relaxed.owl	activation of cellobiose catabolic process|positive regulation of cellobiose catabolism|upregulation of cellobiose catabolism|activation of cellobiose catabolism|up regulation of cellobiose catabolism|up-regulation of cellobiose catabolic process|up regulation of cellobiose catabolic process|upregulation of cellobiose catabolic process|up-regulation of cellobiose catabolism							tt	2012-04-05T12:29:09Z					biological_process											owl:Class	
GO:1900644	biolink:NamedThing	negative regulation of chanoclavine-I biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of chanoclavine-I biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	down regulation of chanoclavine-I formation|down regulation of chanoclavine-I synthesis|down-regulation of chanoclavine-I synthesis|downregulation of chanoclavine-I biosynthetic process|negative regulation of chanoclavine-I anabolism|inhibition of chanoclavine-I synthesis|downregulation of chanoclavine-I formation|inhibition of chanoclavine-I biosynthesis|negative regulation of chanoclavine-I synthesis|down-regulation of chanoclavine-I biosynthesis|negative regulation of chanoclavine-I biosynthesis|down-regulation of chanoclavine-I biosynthetic process|downregulation of chanoclavine-I synthesis|down-regulation of chanoclavine-I anabolism|down regulation of chanoclavine-I anabolism|down regulation of chanoclavine-I biosynthetic process|downregulation of chanoclavine-I biosynthesis|down-regulation of chanoclavine-I formation|inhibition of chanoclavine-I formation|down regulation of chanoclavine-I biosynthesis|negative regulation of chanoclavine-I formation|downregulation of chanoclavine-I anabolism|inhibition of chanoclavine-I anabolism|inhibition of chanoclavine-I biosynthetic process							di	2012-05-22T04:03:30Z					biological_process											owl:Class	
GO:0010840	biolink:NamedThing	regulation of circadian sleep/wake cycle, wakefulness	Any process that modulates the rate, frequency, or extent of the wakeful phase of the circadian sleep/wake cycle. The wakeful phase is the part of the circadian sleep/wake cycle where the organism is not asleep.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0070329	biolink:NamedThing	tRNA seleno-modification	The substitution of a selenium atom for a sulfur atom in a ribonucleotide in a tRNA molecule.	tmpzr1t_l9r_go_relaxed.owl	tRNA base modification to selenouridine													biological_process											owl:Class	
GO:0102499	biolink:NamedThing	SHG alpha-glucan phosphorylase activity	Catalysis of the reaction: hydrogenphosphate + a plant soluble heteroglycan = alpha-D-glucose 1-phosphate + a plant soluble heteroglycan.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-14353|RHEA:41732|EC:2.4.1.1									molecular_function											owl:Class	
GO:0033789	biolink:NamedThing	phenylacetyl-CoA dehydrogenase activity	Catalysis of the reaction: 2 1,4-benzoquinone + H(2)O + phenylacetyl-CoA = 2 hydroquinone + phenylglyoxylyl-CoA.	tmpzr1t_l9r_go_relaxed.owl	phenylacetyl-CoA:quinone oxidoreductase activity|phenylacetyl-CoA:acceptor oxidoreductase activity				MetaCyc:1.17.5.1-RXN|EC:1.17.5.1|KEGG_REACTION:R07222|RHEA:15705									molecular_function											owl:Class	
GO:1901468	biolink:NamedThing	positive regulation of ferulate catabolic process	Any process that activates or increases the frequency, rate or extent of ferulate catabolic process.	tmpzr1t_l9r_go_relaxed.owl	activation of ferulate breakdown|up-regulation of ferulate catabolic process|upregulation of ferulate degradation|up regulation of ferulate catabolism|upregulation of ferulate breakdown|up regulation of ferulate degradation|upregulation of ferulate catabolism|upregulation of ferulate catabolic process|up-regulation of ferulate breakdown|activation of ferulate catabolic process|up regulation of ferulate catabolic process|positive regulation of ferulate breakdown|activation of ferulate catabolism|activation of ferulate degradation|up regulation of ferulate breakdown|up-regulation of ferulate catabolism|up-regulation of ferulate degradation|positive regulation of ferulate catabolism|positive regulation of ferulate degradation							tt	2012-10-02T14:38:56Z					biological_process											owl:Class	
GO:0010511	biolink:NamedThing	regulation of phosphatidylinositol biosynthetic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of phosphatidylinositol.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0008411	biolink:NamedThing	4-hydroxybutyrate CoA-transferase activity	Catalysis of the transfer of a coenzyme A (CoA) group to 4-hydroxybutyrate.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0098821	biolink:NamedThing	BMP receptor activity	Combining with a member of the bone morphogenetic protein (BMP) family, and transmitting a signal across the plasma membrane to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0004675	biolink:NamedThing	transmembrane receptor protein serine/threonine kinase activity	Combining with a signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: ATP protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.	tmpzr1t_l9r_go_relaxed.owl	receptor serine/threonine protein kinase activity|receptor protein serine/threonine kinase activity				EC:2.7.11.30|RHEA:18673|Reactome:R-HSA-170868|Reactome:R-HSA-201476|Reactome:R-HSA-198732|MetaCyc:2.7.11.30-RXN									molecular_function											owl:Class	
GO:0050647	biolink:NamedThing	5-hydroxy-6E,8Z,11Z,14Z-icosatetraenoic acid binding	Binding to 5-hydroxy-6E,8Z,11Z,14Z-icosatetraenoic acid, a straight-chain fatty acid with twenty carbon atoms and four double bonds.	tmpzr1t_l9r_go_relaxed.owl	5-hydroxy-6E,8Z,11Z,14Z-eicosatetraenoic acid binding													molecular_function											owl:Class	
GO:2000467	biolink:NamedThing	positive regulation of glycogen (starch) synthase activity	Any process that activates or increases the frequency, rate or extent of glycogen (starch) synthase activity.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of UDP-glucose-glycogen glucosyltransferase activity|positive regulation of UDPG-glycogen transglucosylase activity|positive regulation of uridine diphosphoglucose-glycogen glucosyltransferase activity|positive regulation of UDP-glucose:glycogen 4-alpha-D-glucosyltransferase activity|positive regulation of UDPglucose:glycogen 4-alpha-D-glucosyltransferase activity|positive regulation of UDP-glycogen synthase activity|positive regulation of UDPG-glycogen synthetase activity|positive regulation of glycogen (starch) synthetase activity							yaf	2011-03-07T04:13:41Z					biological_process											owl:Class	
GO:0031055	biolink:NamedThing	chromatin remodeling at centromere	Dynamic structural changes in centromeric DNA.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0005757	biolink:NamedThing	mitochondrial permeability transition pore complex	A protein complex that connects the inner and outer membranes of animal mitochondria and acts as a pore that can open transiently to allow free diffusion of solutes between the mitochondrial matrix and the cytosol. The pore complex is formed of the voltage-dependent anion channel (VDAC), the adenine nucleotide translocase (ANT) and cyclophilin-D (CyP-D).	tmpzr1t_l9r_go_relaxed.owl	PTPC|MPTP complex|mitochondrial PT pore complex													cellular_component											owl:Class	
GO:1904959	biolink:NamedThing	regulation of cytochrome-c oxidase activity	Any process that modulates the frequency, rate or extent of cytochrome-c oxidase activity.	tmpzr1t_l9r_go_relaxed.owl	regulation of cbb3-type cytochrome c oxidase|regulation of caa3-type cytochrome c oxidase|regulation of NADH cytochrome c oxidase|regulation of ferrocytochrome-c:oxygen oxidoreductase|regulation of complex IV (mitochondrial electron transport) activity|regulation of cytochrome oxidase activity|regulation of ferrocytochrome c oxidase|regulation of cytochrome c oxidase activity|regulation of indophenol oxidase|regulation of aa3-type cytochrome c oxidase|regulation of indophenolase|regulation of ba3-type cytochrome c oxidase|regulation of cytochrome aa3 activity|regulation of warburg's respiratory enzyme activity|regulation of cytochrome a3 activity							tb	2016-02-09T22:18:27Z					biological_process											owl:Class	
GO:1901233	biolink:NamedThing	negative regulation of convergent extension involved in axis elongation	Any process that stops, prevents or reduces the frequency, rate or extent of convergent extension involved in axis elongation.	tmpzr1t_l9r_go_relaxed.owl	down regulation of convergent extension involved in axis elongation|downregulation of convergent extension involved in axis elongation|down-regulation of convergent extension involved in axis elongation|inhibition of convergent extension involved in axis elongation							vk	2012-08-07T14:22:11Z					biological_process											owl:Class	
GO:1902163	biolink:NamedThing	negative regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator	Any process that stops, prevents or reduces the frequency, rate or extent of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator.	tmpzr1t_l9r_go_relaxed.owl	inhibition of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator|downregulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator|down-regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator|down regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator							lb	2013-05-22T12:39:23Z					biological_process											owl:Class	
GO:0035964	biolink:NamedThing	COPI-coated vesicle budding	The evagination of a Golgi membrane, resulting in formation of a COPI-coated vesicle.	tmpzr1t_l9r_go_relaxed.owl	COPI vesicle budding							bf	2011-08-01T11:32:23Z					biological_process											owl:Class	
GO:0051866	biolink:NamedThing	general adaptation syndrome	General adaptation syndrome is the set of changes in various organ systems of the body, especially the pituitary-endocrine system, in response to a wide range of strong external stimuli, both physiological and psychological. It is described as having three stages: alarm reaction, where the body detects the external stimulus; adaptation, where the body engages defensive countermeasures against the stressor; and exhaustion, where the body begins to run out of defenses.	tmpzr1t_l9r_go_relaxed.owl	general adaptation syndrome, physiological process|general adaptation syndrome, physiological response|physiological response during general adaptation syndrome|physiological process during general adaptation syndrome											GO:0051868		biological_process											owl:Class	
GO:0033555	biolink:NamedThing	multicellular organismal response to stress	Any process that results in a change in state or activity of a multicellular organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0038165	biolink:NamedThing	oncostatin-M-mediated signaling pathway	A series of molecular signals initiated by the binding of oncostatin-M (OSM) to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. OSM can signal via at least two different receptors (a specific receptor and a LIF receptor) to activate different downstream signal transduction pathways.	tmpzr1t_l9r_go_relaxed.owl	OSM signaling pathway|oncostatin-M signaling pathway							bf	2012-05-14T02:54:30Z					biological_process											owl:Class	
GO:0071609	biolink:NamedThing	chemokine (C-C motif) ligand 5 production	The appearance of chemokine (C-C motif) ligand 5 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	tmpzr1t_l9r_go_relaxed.owl	CCL5 production|RANTES production|Regulated upon Activation, Normal T-cell Expressed, and Secreted production							mah	2010-02-05T04:32:35Z					biological_process											owl:Class	
GO:0042637	biolink:NamedThing	catagen	The regression phase of the hair cycle during which cell proliferation ceases, the hair follicle shortens, and an anchored club hair is produced.	tmpzr1t_l9r_go_relaxed.owl	hair regression					Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase. To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).								biological_process											owl:Class	
GO:0044851	biolink:NamedThing	hair cycle phase	The cyclical periods of growth (anagen), regression (catagen), quiescence (telogen), and shedding (exogen) in the life of a hair; one of the collection or mass of filaments growing from the skin of an animal, and forming a covering for a part of the head or for any part or the whole of the body.	tmpzr1t_l9r_go_relaxed.owl						Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase. To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).		jl	2014-07-16T14:22:09Z					biological_process											owl:Class	
GO:0072004	biolink:NamedThing	kidney field specification	The process that results in the delineation of regions of the embryo into the area in which the kidney rudiment will develop.	tmpzr1t_l9r_go_relaxed.owl	specification of kidney anlage							mah	2010-01-25T11:24:33Z					biological_process											owl:Class	
GO:0033284	biolink:NamedThing	ATPase-coupled carboxylic acid transmembrane transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + carboxylic acid(out/in) = ADP + phosphate + carboxylic acid(in/out).	tmpzr1t_l9r_go_relaxed.owl	carboxylic acid-transporting ATPase activity|ATP-dependent carboxylic acid transporter activity													molecular_function											owl:Class	
GO:1903075	biolink:NamedThing	pyridoxine import across plasma membrane	The directed movement of pyridoxine from outside of a cell, across the plasma membrane and into the cytosol.	tmpzr1t_l9r_go_relaxed.owl	pyridoxine import into cell							mah	2014-05-29T15:04:14Z					biological_process											owl:Class	
GO:1904117	biolink:NamedThing	cellular response to vasopressin	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vasopressin stimulus.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-04-06T19:39:48Z					biological_process											owl:Class	
GO:0003428	biolink:NamedThing	chondrocyte intercalation involved in growth plate cartilage morphogenesis	The orderly movement of a chondrocyte from one site to another that contributes to the shaping of growth plate cartilage in an endochondral bone.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-12-22T11:52:32Z					biological_process											owl:Class	
GO:0097639	biolink:NamedThing	L-lysine import across plasma membrane	The directed movement of L-lysine from outside of a cell, across the plasma membrane and into the cytosol.	tmpzr1t_l9r_go_relaxed.owl	L-lysine import into cell							pr	2014-09-03T09:32:57Z			GO:1903410		biological_process											owl:Class	
GO:1902272	biolink:NamedThing	regulation of (R)-carnitine transmembrane transport	Any process that modulates the frequency, rate or extent of (R)-carnitine transmembrane transport.	tmpzr1t_l9r_go_relaxed.owl								mcc	2013-07-01T13:13:11Z					biological_process											owl:Class	
GO:0033312	biolink:NamedThing	chlorophyll a biosynthetic process via geranylgeranyl-chlorophyll a	The chemical reactions and pathways leading to the formation of chlorophyll a, via the intermediate geranylgeranyl-chlorophyll a.	tmpzr1t_l9r_go_relaxed.owl	chlorophyll a synthesis via geranylgeranyl-chlorophyll a|chlorophyll a anabolism via geranylgeranyl-chlorophyll a|chlorophyll a formation via geranylgeranyl-chlorophyll a|chlorophyll a biosynthesis via geranylgeranyl-chlorophyll a				MetaCyc:PWY-5064									biological_process											owl:Class	
GO:0018819	biolink:NamedThing	lactoyl-CoA dehydratase activity	Catalysis of the reaction: lactoyl-CoA = acryloyl-CoA + H2O.	tmpzr1t_l9r_go_relaxed.owl	lactyl-coenzyme A dehydrase activity|acrylyl coenzyme A hydratase activity|lactyl CoA dehydratase activity|lactoyl-CoA hydro-lyase activity|lactoyl coenzyme A dehydratase activity|lactoyl-CoA hydro-lyase (acryloyl-CoA-forming)				MetaCyc:RXN-781|RHEA:21056|EC:4.2.1.54|UM-BBD_reactionID:r0086|MetaCyc:LACTOYL-COA-DEHYDRATASE-RXN									molecular_function											owl:Class	
GO:0019061	biolink:NamedThing	uncoating of virus	The process by which an incoming virus is disassembled in the host cell to release a replication-competent viral genome.	tmpzr1t_l9r_go_relaxed.owl	viral uncoating													biological_process											owl:Class	
GO:0002037	biolink:NamedThing	negative regulation of L-glutamate import across plasma membrane	Any process that stops, prevents or reduces the frequency, rate or extent of L-glutamate import into a cell.	tmpzr1t_l9r_go_relaxed.owl	down regulation of L-glutamate uptake|negative regulation of L-glutamate transport|negative regulation of L-glutamate import|inhibition of L-glutamate uptake|down regulation of L-glutamate transport|down regulation of L-glutamate import|inhibition of L-glutamate import|downregulation of L-glutamate transport|regulation of L-glutamate import|negative regulation of L-glutamate uptake|down-regulation of L-glutamate uptake|inhibition of L-glutamate transport|downregulation of L-glutamate import|downregulation of L-glutamate uptake|down-regulation of L-glutamate transport|down-regulation of L-glutamate import							al	2012-06-13T07:34:30Z			GO:1900921		biological_process											owl:Class	
GO:0048632	biolink:NamedThing	negative regulation of skeletal muscle tissue growth	Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle growth.	tmpzr1t_l9r_go_relaxed.owl	downregulation of skeletal muscle growth|inhibition of skeletal muscle growth|down regulation of skeletal muscle growth|down-regulation of skeletal muscle growth													biological_process											owl:Class	
GO:0009087	biolink:NamedThing	methionine catabolic process	The chemical reactions and pathways resulting in the breakdown of methionine (2-amino-4-(methylthio)butanoic acid), a sulfur-containing, essential amino acid found in peptide linkage in proteins.	tmpzr1t_l9r_go_relaxed.owl	methionine degradation|methionine breakdown|methionine catabolism				UM-BBD_pathwayID:met									biological_process											owl:Class	
GO:0047967	biolink:NamedThing	glycyrrhizinate beta-glucuronidase activity	Catalysis of the reaction: glycyrrhizate + H(2)O = 2-(beta-D-glucuronosyl)-D-glucuronate + glycyrrhetinate.	tmpzr1t_l9r_go_relaxed.owl	glycyrrhizin beta-hydrolase activity|glycyrrhizin hydrolase activity|glycyrrhizinic acid hydrolase activity|glycyrrhizinate b-glucuronidase activity|glycyrrhizinate glucuronosylhydrolase activity				MetaCyc:GLYCYRRHIZINATE-BETA-GLUCURONIDASE-RXN|KEGG_REACTION:R03906|EC:3.2.1.128|RHEA:17369									molecular_function											owl:Class	
GO:1901246	biolink:NamedThing	regulation of lung ciliated cell differentiation	Any process that modulates the frequency, rate or extent of lung ciliated cell differentiation.	tmpzr1t_l9r_go_relaxed.owl								vk	2012-08-08T08:58:34Z					biological_process											owl:Class	
GO:1904874	biolink:NamedThing	positive regulation of telomerase RNA localization to Cajal body	Any process that activates or increases the frequency, rate or extent of telomerase RNA localization to Cajal body.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of telomerase RNA localization to Cajal body|upregulation of telomerase RNA localization to Cajal body|activation of telomerase RNA localization to Cajal body|up regulation of telomerase RNA localization to Cajal body							nc	2015-12-18T11:28:34Z					biological_process											owl:Class	
GO:0043466	biolink:NamedThing	pyrimidine nucleobase fermentation	The anaerobic conversion of pyrimidine nucleobases, yielding energy in the form of ATP.	tmpzr1t_l9r_go_relaxed.owl	pyrimidine fermentation|pyrimidine base fermentation													biological_process											owl:Class	
GO:1904471	biolink:NamedThing	negative regulation of endothelin production	Any process that stops, prevents or reduces the frequency, rate or extent of endothelin production.	tmpzr1t_l9r_go_relaxed.owl	down regulation of EDN2 secretion|downregulation of endothelin-2 secretion|downregulation of EDN3 secretion|down regulation of endothelin secretion|downregulation of endothelin secretion|down regulation of EDN1 secretion|down regulation of EDN3 secretion|inhibition of EDN2 secretion|down-regulation of endothelin-3 secretion|inhibition of endothelin-2 secretion|negative regulation of EDN2 secretion|negative regulation of endothelin-2 secretion|inhibition of EDN3 secretion|down-regulation of EDN2 secretion|down-regulation of endothelin-1 secretion|down regulation of endothelin-2 secretion|down regulation of endothelin-1 secretion|down-regulation of EDN1 secretion|negative regulation of endothelin-1 secretion|down regulation of endothelin-3 secretion|down-regulation of endothelin secretion|inhibition of EDN1 secretion|inhibition of endothelin-3 secretion|negative regulation of endothelin secretion|downregulation of endothelin-3 secretion|negative regulation of EDN1 secretion|inhibition of endothelin-1 secretion|downregulation of EDN2 secretion|negative regulation of endothelin-3 secretion|inhibition of endothelin secretion|negative regulation of EDN3 secretion|downregulation of endothelin-1 secretion|down-regulation of EDN3 secretion|downregulation of EDN1 secretion|down-regulation of endothelin-2 secretion							sl	2015-07-09T19:58:03Z					biological_process											owl:Class	
GO:0034497	biolink:NamedThing	protein localization to phagophore assembly site	Any process in which a protein is transported to, or maintained at, the phagophore assembly site (PAS).	tmpzr1t_l9r_go_relaxed.owl	protein localization to PAS|protein localization to pre-autophagosomal structure|protein localisation to phagophore assembly site													biological_process											owl:Class	
GO:0014912	biolink:NamedThing	negative regulation of smooth muscle cell migration	Any process that stops, prevents, or reduces the frequency, rate or extent of smooth muscle cell migration.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:2000149	biolink:NamedThing	negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis	Any process that stops, prevents, or reduces the frequency, rate or extent of planar cell polarity pathway involved in ventricular septum morphogenesis.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-10-01T07:09:53Z					biological_process											owl:Class	
GO:2000148	biolink:NamedThing	regulation of planar cell polarity pathway involved in ventricular septum morphogenesis	Any process that modulates the frequency, rate or extent of planar cell polarity pathway involved in ventricular septum morphogenesis.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-10-01T07:09:49Z					biological_process											owl:Class	
GO:0046244	biolink:NamedThing	salicylic acid catabolic process	The chemical reactions and pathways resulting in the breakdown of salicylic acid (2-hydroxybenzoic acid), a derivative of benzoic acid.	tmpzr1t_l9r_go_relaxed.owl	salicylic acid catabolism|salicylic acid breakdown|salicylic acid degradation													biological_process											owl:Class	
GO:0034056	biolink:NamedThing	estrogen response element binding	Binding to an estrogen response element (ERE), a conserved sequence found in the promoters of genes whose expression is regulated in response to estrogen.	tmpzr1t_l9r_go_relaxed.owl	ERE binding					Note that as agreed during the transcription overhaul, terms specifying binding to specific transcription regulatory motifs are no longer being created. The level of specificity GO has decided to go to is the "core promoter", "core promoter proximal region" and "enhancer". To capture more detail, please consider using column 16.								molecular_function											owl:Class	
GO:0120175	biolink:NamedThing	regulation of torso signaling pathway	Any process that modulates the frequency, rate or extent of the torso signaling pathway.	tmpzr1t_l9r_go_relaxed.owl								krc	2018-06-07T16:47:42Z					biological_process											owl:Class	
GO:0045613	biolink:NamedThing	regulation of plasmatocyte differentiation	Any process that modulates the frequency, rate or extent of plasmatocyte differentiation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0034052	biolink:NamedThing	positive regulation of plant-type hypersensitive response	Any process that activates or increases the frequency, rate or extent of the hypersensitive response in a plant.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of HR-PCD|activation of plant-type hypersensitive response|up-regulation of plant-type hypersensitive response|upregulation of plant-type hypersensitive response|positive regulation of HR|positive regulation of plant hypersensitive response|up regulation of plant-type hypersensitive response|stimulation of plant-type hypersensitive response													biological_process											owl:Class	
GO:0019350	biolink:NamedThing	teichoic acid biosynthetic process	The chemical reactions and pathways resulting in the formation of teichoic acid, any polymer occurring in the cell wall, membrane or capsule of Gram-positive bacteria and containing chains of glycerol phosphate or ribitol phosphate residues.	tmpzr1t_l9r_go_relaxed.owl	teichoic acid biosynthesis|teichoic acid synthesis|teichoic acid formation|teichoic acid anabolism				MetaCyc:TEICHOICACID-PWY									biological_process											owl:Class	
GO:0010314	biolink:NamedThing	phosphatidylinositol-5-phosphate binding	Binding to phosphatidylinositol-5-phosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 5' position.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0090234	biolink:NamedThing	regulation of kinetochore assembly	Any process that modulates the rate, frequency, or extent of kinetochore assembly, the aggregation, arrangement and bonding together of a set of components to form the kinetochore, a multisubunit complex that is located at the centromeric region of DNA and provides an attachment point for the spindle microtubules.	tmpzr1t_l9r_go_relaxed.owl	regulation of chromosome-kinetochore attachment							tb	2010-01-20T10:46:56Z					biological_process											owl:Class	
GO:0021710	biolink:NamedThing	cerebellar stellate cell differentiation	The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature cerebellar stellate cell. Differentiation includes the processes involved in commitment of a neuroblast to a cerebellar stellate cell fate. A cerebellar stellate cell is an inhibitory GABAergic interneuron found in the cerebellar cortex.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1904900	biolink:NamedThing	negative regulation of myosin II filament organization	Any process that stops, prevents or reduces the frequency, rate or extent of myosin II filament organization.	tmpzr1t_l9r_go_relaxed.owl	downregulation of myosin II filament organisation|down-regulation of myosin II filament assembly or disassembly|down-regulation of myosin II polymerization or depolymerization|negative regulation of myosin II filament assembly or disassembly|down regulation of myosin II filament assembly or disassembly|inhibition of myosin II filament assembly or disassembly|inhibition of myosin II polymerization or depolymerization|down-regulation of myosin II filament organization|downregulation of myosin II polymerization or depolymerization|down regulation of myosin II polymerization or depolymerization|inhibition of myosin II filament organization|inhibition of myosin II filament organisation|negative regulation of myosin II filament organisation|down regulation of myosin II filament organisation|down regulation of myosin II filament organization|downregulation of myosin II filament assembly or disassembly|down-regulation of myosin II filament organisation|downregulation of myosin II filament organization|negative regulation of myosin II polymerization or depolymerization							mec	2016-01-15T09:04:54Z					biological_process											owl:Class	
GO:0009452	biolink:NamedThing	7-methylguanosine RNA capping	The sequence of enzymatic reactions by which the 5' cap structure, an inverted 7-methylguanosine linked via a 5'-5' triphosphate bridge (m7G(5')ppp(5')X) to the first transcribed residue, is added to a nascent transcript.	tmpzr1t_l9r_go_relaxed.owl	RNA capping|m(7)G RNA capping													biological_process											owl:Class	
GO:0036260	biolink:NamedThing	RNA capping	The sequence of enzymatic reactions by which a cap structure is added to the 5' end of nascent RNA polymerase transcripts. Examples of RNA capping include 7-methyl-G caps found on all RNA polymerase II transcripts and nucleotide-containing cofactor caps, such as NAD(H) or FAD, found on bacterial trancripts.	tmpzr1t_l9r_go_relaxed.owl								bf	2012-06-15T02:10:23Z					biological_process											owl:Class	
GO:0009254	biolink:NamedThing	peptidoglycan turnover	The continual breakdown and regeneration of peptidoglycan required to maintain the cell wall.	tmpzr1t_l9r_go_relaxed.owl	murein turnover											GO:0009287		biological_process											owl:Class	
GO:0150038	biolink:NamedThing	postsynaptic dense core vesicle exocytosis	The secretion of molecules (e.g. neuropeptides, insulin-related peptides or neuromodulators such as serotonin and dopamine) contained within a postsynaptic dense core vesicle by fusion of the granule with the plasma membrane of the postsynapse in response to increased cytosolic calcium levels.	tmpzr1t_l9r_go_relaxed.owl								bc	2018-04-18T14:32:16Z					biological_process											owl:Class	
GO:0099011	biolink:NamedThing	neuronal dense core vesicle exocytosis	The secretion of molecules (e.g. neuropeptides, insulin-related peptides or neuromodulators such as serotonin and dopamine) contained within a neuronal dense core vesicle by fusion of the granule with the plasma membrane of a neuron in response to increased cytosolic calcium levels.	tmpzr1t_l9r_go_relaxed.owl								kmv						biological_process											owl:Class	
GO:0001978	biolink:NamedThing	regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback	The process that modulates blood pressure by sensing the amount of stretch occurring in large arteries and responding to the input via central nervous system control.	tmpzr1t_l9r_go_relaxed.owl	carotid sinus baroreceptor feedback regulation of systemic arterial blood pressure|baroreceptor feedback control of blood pressure|baroreceptor pressure buffer system													biological_process											owl:Class	
GO:0006590	biolink:NamedThing	thyroid hormone generation	The formation of either of the compounds secreted by the thyroid gland, mainly thyroxine and triiodothyronine. This is achieved by the iodination and joining of tyrosine molecules to form the precursor thyroglobin, proteolysis of this precursor gives rise to the thyroid hormones.	tmpzr1t_l9r_go_relaxed.owl						Note that this term does not fall under the general GO definition for biosynthetic processes, which is 'The chemical reactions and pathways resulting in the formation of... ', because thyroid hormones can only be formed by the proteolysis of a larger molecule (see term definition). The word 'generation' is therefore used in place of biosynthesis.								biological_process											owl:Class	
GO:0042333	biolink:NamedThing	chemotaxis to oxidizable substrate	The directed movement of a motile cell or organism in response to the presence of an oxidizable substrate, for example, fructose.	tmpzr1t_l9r_go_relaxed.owl	taxis in response to oxidizable substrate													biological_process											owl:Class	
GO:1904782	biolink:NamedThing	negative regulation of NMDA glutamate receptor activity	Any process that stops, prevents or reduces the frequency, rate or extent of NMDA glutamate receptor activity.	tmpzr1t_l9r_go_relaxed.owl	downregulation of NMDA glutamate receptor activity|down-regulation of NMDA receptor|down regulation of NMDA receptor|down-regulation of N-methyl-D-aspartate selective glutamate receptor activity|down regulation of NMDA glutamate receptor activity|negative regulation of N-methyl-D-aspartate selective glutamate receptor activity|inhibition of NMDA receptor|downregulation of N-methyl-D-aspartate selective glutamate receptor activity|down regulation of N-methyl-D-aspartate selective glutamate receptor activity|inhibition of NMDA glutamate receptor activity|downregulation of NMDA receptor|down-regulation of NMDA glutamate receptor activity|inhibition of N-methyl-D-aspartate selective glutamate receptor activity|negative regulation of NMDA receptor							mr	2015-10-30T19:39:31Z					biological_process											owl:Class	
GO:0005026	biolink:NamedThing	transforming growth factor beta receptor activity, type II	Combining with transforming growth factor beta to initiate a change in cell activity; upon ligand binding, binds to and catalyzes the phosphorylation of a type I TGF-beta receptor.	tmpzr1t_l9r_go_relaxed.owl	type II transforming growth factor beta receptor activity|type II TGFbeta receptor activity|type II TGF-beta receptor activity|transforming growth factor beta ligand binding to type II receptor				Reactome:R-HSA-170843									molecular_function											owl:Class	
GO:0005024	biolink:NamedThing	transforming growth factor beta-activated receptor activity	Combining with a transforming growth factor beta (TGFbeta) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: ATP protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.	tmpzr1t_l9r_go_relaxed.owl	transforming growth factor beta receptor activity|TGFbetaR|TGFbeta receptor activity|TGFbeta-activated receptor activity|TGF-beta receptor activity					Note that this term represents an activity and not a gene product, and should only be used when the receptor binds the ligand TGFbeta. For binding to other growth factors, consider annotating to terms under 'transmembrane signaling receptor activity ; GO:0004888.								molecular_function											owl:Class	
GO:0042860	biolink:NamedThing	achromobactin metabolic process	The chemical reactions and pathways involving achromobactin, a citrate siderophore.	tmpzr1t_l9r_go_relaxed.owl	achromobactin metabolism													biological_process											owl:Class	
GO:0035888	biolink:NamedThing	isoguanine deaminase activity	Catalysis of the reaction: isoguanine + H2O = xanthine + NH3.	tmpzr1t_l9r_go_relaxed.owl	2-oxoadenine deaminase activity|2-hydroxyadenine deaminase activity							bf	2011-06-14T02:15:53Z					molecular_function											owl:Class	
GO:0047784	biolink:NamedThing	cortisol O-acetyltransferase activity	Catalysis of the reaction: acetyl-CoA + cortisol = CoA + cortisol 21-acetate.	tmpzr1t_l9r_go_relaxed.owl	corticosteroid-21-O-acetyltransferase activity|corticosteroid acetyltransferase activity|cortisol acetyltransferase activity|acetyl-CoA:cortisol O-acetyltransferase activity				KEGG_REACTION:R02837|EC:2.3.1.27|RHEA:17073|MetaCyc:CORTISOL-O-ACETYLTRANSFERASE-RXN									molecular_function											owl:Class	
GO:0046306	biolink:NamedThing	alkanesulfonate catabolic process	The chemical reactions and pathways resulting in the breakdown of alkanesulfonates, the anion of alkanesulfonic acids, sulfonic acid derivatives containing an aliphatic hydrocarbon group.	tmpzr1t_l9r_go_relaxed.owl	alkanesulphonate catabolic process|alkanesulfonate degradation|alkanesulphonate catabolism|alkanesulfonate catabolism|alkanesulfonate breakdown													biological_process											owl:Class	
GO:1905180	biolink:NamedThing	positive regulation of cardiac muscle tissue regeneration	Any process that activates or increases the frequency, rate or extent of cardiac muscle tissue regeneration.	tmpzr1t_l9r_go_relaxed.owl	up regulation of cardiac muscle tissue regeneration|up-regulation of cardiac muscle tissue regeneration|upregulation of cardiac muscle tissue regeneration|activation of cardiac muscle tissue regeneration							rph	2016-05-05T11:31:06Z					biological_process											owl:Class	
GO:0072555	biolink:NamedThing	17-beta-ketosteroid reductase activity	Catalysis of the reaction: a 17-beta-ketosteroid + NADPH + H+ = a 17-beta-hydroxysteroid + NADP+.	tmpzr1t_l9r_go_relaxed.owl	7beta-ketosteroid reductase activity|17-beta-ketosteroid reductase (NADPH) activity							mah	2011-01-27T11:36:14Z					molecular_function											owl:Class	
GO:0090462	biolink:NamedThing	ornithine homeostasis	Any process involved in the maintenance of an internal steady state of ornithine within an organism or cell.	tmpzr1t_l9r_go_relaxed.owl								tb	2012-09-24T14:22:02Z					biological_process											owl:Class	
GO:0003332	biolink:NamedThing	negative regulation of extracellular matrix constituent secretion	Any process that decreases the rate, frequency, or extent the controlled release of molecules that form the extracellular matrix, including carbohydrates and glycoproteins by a cell or a group of cells.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-11-02T02:13:49Z					biological_process											owl:Class	
GO:0009068	biolink:NamedThing	aspartate family amino acid catabolic process	The chemical reactions and pathways resulting in the breakdown of amino acids of the aspartate family, comprising asparagine, aspartate, lysine, methionine and threonine.	tmpzr1t_l9r_go_relaxed.owl	aspartate family amino acid breakdown|aspartate family amino acid catabolism|aspartate family amino acid degradation													biological_process											owl:Class	
GO:0061399	biolink:NamedThing	positive regulation of transcription from RNA polymerase II promoter in response to cobalt ion	Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter in response to a cobalt ion stimulus.	tmpzr1t_l9r_go_relaxed.owl								dph	2012-01-10T09:28:52Z					biological_process											owl:Class	
GO:0019338	biolink:NamedThing	pentachlorophenol catabolic process	The chemical reactions and pathways resulting in the breakdown of pentachlorophenol, a chlorinated insecticide and fungicide used primarily to protect timber from fungal rot and wood boring insects. Pentachlorophenol is significantly toxic to mammals, plants, and many microorganisms.	tmpzr1t_l9r_go_relaxed.owl	pentachlorophenol catabolism|pentachlorophenol degradation|pentachlorophenol breakdown				MetaCyc:PCPDEG-PWY									biological_process											owl:Class	
GO:1990002	biolink:NamedThing	methylglyoxal reductase (NADPH-dependent, acetol producing)	Catalysis of the reaction: H+ + methylglyoxal + NADPH <=> hydroxyacetone + NADP+.	tmpzr1t_l9r_go_relaxed.owl					RHEA:27986			jl	2012-12-05T15:55:06Z					molecular_function											owl:Class	
GO:0097128	biolink:NamedThing	cyclin D1-CDK4 complex	A protein complex consisting of cyclin D1 and cyclin-dependent kinase 4 (CDK4). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner.	tmpzr1t_l9r_go_relaxed.owl								pr	2011-08-01T01:48:36Z					cellular_component											owl:Class	
GO:0140202	biolink:NamedThing	polyamine import across plasma membrane	The directed movement of a polyamine from outside of a cell, across the plasma membrane and into the cytosol.	tmpzr1t_l9r_go_relaxed.owl								pg	2018-02-20T10:24:54Z					biological_process											owl:Class	
GO:1900499	biolink:NamedThing	positive regulation of butyryl-CoA catabolic process to butanol	Any process that activates or increases the frequency, rate or extent of butyryl-CoA catabolic process to butanol.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of butyryl-CoA catabolic process to butanol|up regulation of butyryl-CoA catabolic process to butanol|up regulation of butyryl-CoA catabolism to butanol|positive regulation of butyryl-CoA catabolism to butanol|up-regulation of butyryl-CoA catabolism to butanol|upregulation of butyryl-CoA catabolic process to butanol|upregulation of butyryl-CoA catabolism to butanol|activation of butyryl-CoA catabolic process to butanol|activation of butyryl-CoA catabolism to butanol							tt	2012-05-02T03:53:40Z					biological_process											owl:Class	
GO:0110084	biolink:NamedThing	negative regulation of protein localization to cell division site involved in mitotic actomyosin contractile ring assembly	Any process that stops, prevents, or reduces the frequency, rate or extent of protein localization to cell division site involved in mitotic actomyosin contractile ring assembly.	tmpzr1t_l9r_go_relaxed.owl								kmv	2018-02-01T19:33:51Z					biological_process											owl:Class	
GO:0034602	biolink:NamedThing	oxoglutarate dehydrogenase (NAD+) activity	Catalysis of the reaction: 2-oxoglutarate + CoA + NAD+ = succinyl-CoA + CO2 + NADH.	tmpzr1t_l9r_go_relaxed.owl					RHEA:27786|KEGG_REACTION:R08549|Reactome:R-HSA-71401|EC:1.2.1.105|MetaCyc:2OXOGLUTARATEDEH-RXN|Reactome:R-HSA-71037									molecular_function											owl:Class	
GO:0045271	biolink:NamedThing	respiratory chain complex I	Respiratory chain complex I is an enzyme of the respiratory chain. It consists of several polypeptide chains and is L-shaped, with a horizontal arm lying in the membrane and a vertical arm that projects into the matrix. The electrons of NADH enter the chain at this complex.	tmpzr1t_l9r_go_relaxed.owl	electron transport complex I|NADH dehydrogenase complex (ubiquinone)|NADH dehydrogenase (ubiquinone) complex|NADH-Q oxidoreductase complex					Note that this term represents a location and not a function; the activity possessed by this complex is mentioned in the definition for the purpose of describing and distinguishing the complex. The function possessed by this complex is represented by the molecular function term 'NADH dehydrogenase (ubiquinone) activity ; GO:0008137'.						GO:0045279		cellular_component											owl:Class	
GO:0046532	biolink:NamedThing	regulation of photoreceptor cell differentiation	Any process that modulates the frequency, rate or extent of photoreceptor cell differentiation. An example of this process is found in Drosophila melanogaster.	tmpzr1t_l9r_go_relaxed.owl	regulation of photoreceptor differentiation											GO:0045673		biological_process											owl:Class	
GO:0061692	biolink:NamedThing	cellular detoxification of hydrogen peroxide	Any process that reduces or removes the toxicity of hydrogen peroxide in a cell. These include transport of hydrogen peroxide away from sensitive areas and to compartments or complexes whose purpose is sequestration.	tmpzr1t_l9r_go_relaxed.owl								dph	2015-05-05T12:46:20Z					biological_process											owl:Class	
GO:0033319	biolink:NamedThing	UDP-D-xylose metabolic process	The chemical reactions and pathways involving UDP-D-xylose, uridinediphosphoxylose, a substance composed of xylose in glycosidic linkage with uridine diphosphate.	tmpzr1t_l9r_go_relaxed.owl	UDP-D-xylose metabolism													biological_process											owl:Class	
GO:0003290	biolink:NamedThing	atrial septum secundum morphogenesis	The process in which anatomical structure of an atrial septum secundum is generated and organized.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-10-20T10:33:57Z					biological_process											owl:Class	
GO:0102862	biolink:NamedThing	1-18:2-2-18:2-sn-glycerol-3-phosphocholine desaturase activity (SN2-18:3 forming)	Catalysis of the reaction: 1-18:2-2-18:2-sn-glycerol-3-phosphocholine + O2 + a reduced electron acceptor = 1-18:2-2-18:3-phosphatidylcholine + 2 H2O + an oxidized electron acceptor.	tmpzr1t_l9r_go_relaxed.owl					EC:1.14.19.25|MetaCyc:RXN-8329									molecular_function											owl:Class	
GO:0015743	biolink:NamedThing	malate transport	The directed movement of malate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	mitochondrial alpha-ketoglutarate/malate transport													biological_process											owl:Class	
GO:0009961	biolink:NamedThing	response to 1-aminocyclopropane-1-carboxylic acid	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 1-aminocyclopropane-1-carboxylic acid stimulus.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0019542	biolink:NamedThing	propionate biosynthetic process	The chemical reactions and pathways resulting in the formation of propionate, the anion derived from propionic acid.	tmpzr1t_l9r_go_relaxed.owl	propionate synthesis|propionate anabolism|propionate formation|propionate biosynthesis													biological_process											owl:Class	
GO:0018497	biolink:NamedThing	1-chloro-2,2-bis(4-chlorophenyl)ethane dehydrogenase activity	Catalysis of the reaction: 1-chloro-2,2-bis(4-chlorophenyl)ethene + 2 H+ + 2 e- = 1-chloro-2,2-bis(4-chlorophenyl)ethane. 1-chloro-2,2-bis(4-chlorophenyl)ethene is also known as DDMU; 1-chloro-2,2-bis(4-chlorophenyl)ethane is also known as DDMS.	tmpzr1t_l9r_go_relaxed.owl	DDMS dehydrogenase activity				UM-BBD_reactionID:r0514									molecular_function											owl:Class	
GO:0002871	biolink:NamedThing	regulation of natural killer cell tolerance induction	Any process that modulates the frequency, rate, or extent of natural killer cell tolerance induction.	tmpzr1t_l9r_go_relaxed.owl	regulation of NK cell tolerance induction													biological_process											owl:Class	
GO:0009715	biolink:NamedThing	chalcone biosynthetic process	The chemical reactions and pathways resulting in the formation of chalcone, phenyl steryl ketone or its hydroxylated derivatives.	tmpzr1t_l9r_go_relaxed.owl	chalcone anabolism|chalcone biosynthesis|chalcone synthesis|chalcone formation													biological_process											owl:Class	
GO:0009871	biolink:NamedThing	jasmonic acid and ethylene-dependent systemic resistance, ethylene mediated signaling pathway	The series of molecular signals mediated by ethylene (ethene) involved in jasmonic acid/ethylene dependent systemic resistance.	tmpzr1t_l9r_go_relaxed.owl	jasmonic acid/ethene-dependent systemic resistance, ethene mediated signaling pathway|jasmonic acid/ethene-dependent systemic resistance, ethene mediated signalling pathway|ethylene mediated signaling pathway (jasmonic acid/ethylene-dependent systemic resistance)|jasmonic acid and ethene-dependent systemic resistance, ethene mediated signaling pathway|ethene mediated signaling pathway (jasmonic acid/ethene-dependent systemic resistance)|jasmonic acid/ethylene-dependent systemic resistance, ethylene mediated signaling pathway|jasmonic acid/ethylene-dependent systemic resistance, ethylene mediated signalling pathway													biological_process											owl:Class	
GO:0071520	biolink:NamedThing	actomyosin contractile ring assembly actin filament bundle convergence	A process of actin filament bundle distribution that occurs in the context of assembling an actomyosin contractile ring during cytokinesis, and that results in the compaction of actin filaments into a tight ring.	tmpzr1t_l9r_go_relaxed.owl	actin filament bundle convergence involved in cytokinetic actomyosin contractile ring assembly|actin filament bundle convergence involved in actomyosin contractile ring formation							mah	2010-01-06T05:33:16Z					biological_process											owl:Class	
GO:2000689	biolink:NamedThing	actomyosin contractile ring assembly actin filament organization	An actin filament organization process that contributes to actomyosin contractile ring assembly during cytokinesis.	tmpzr1t_l9r_go_relaxed.owl	actin filament organization of cytokinesis, actomyosin contractile ring assembly|actin filament organization of cytokinesis, contractile ring assembly|regulation of actin filament localization of constriction ring assembly|regulation of actin filament localization of cytokinesis, actomyosin ring biosynthesis|actin filament organisation of cytokinesis, actomyosin ring formation|actin filament organization involved in cytokinetic actomyosin contractile ring assembly|actin filament organisation of contractile ring assembly|actin filament organization of contractile ring assembly|regulation of actin filament localization of cytokinesis, contractile ring assembly|actin filament organization of cytokinesis, actomyosin ring formation|actin filament organization of cytokinesis, actomyosin contractile ring formation|actin filament organisation of cytokinesis, actomyosin contractile ring formation|actin filament organization of cytokinesis, actomyosin ring biosynthesis|actin filament organisation of constriction ring assembly|regulation of actin filament localization of cytokinesis, actomyosin contractile ring formation|actin filament organisation of cytokinesis, contractile ring assembly|actin filament organization of constriction ring assembly|regulation of actin filament localization of cytokinesis, actomyosin contractile ring assembly|regulation of actin filament localization of contractile ring assembly|actin filament organisation of cytokinesis, actomyosin ring biosynthesis|actin filament organisation of cytokinesis, actomyosin contractile ring assembly|regulation of actin filament localization of cytokinesis, actomyosin ring formation							mah	2011-05-17T11:48:12Z					biological_process											owl:Class	
GO:0021590	biolink:NamedThing	cerebellum maturation	A developmental process, independent of morphogenetic (shape) change, that is required for the cerebellum to attain its fully functional state. The cerebellum is the portion of the brain in the back of the head between the cerebrum and the pons. The cerebellum controls balance for walking and standing, modulates the force and range of movement and is involved in the learning of motor skills.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0033004	biolink:NamedThing	negative regulation of mast cell activation	Any process that stops, prevents, or reduces the frequency, rate, or extent of mast cell activation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:2000999	biolink:NamedThing	positive regulation of cellulose catabolic process	Any process that activates or increases the frequency, rate or extent of cellulose catabolic process.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of cellulose catabolism|positive regulation of cellulose breakdown|positive regulation of cellulose degradation							tt	2011-08-08T03:21:30Z					biological_process											owl:Class	
GO:0000148	biolink:NamedThing	1,3-beta-D-glucan synthase complex	A protein complex that catalyzes the transfer of a glucose group from UDP-glucose to a (1->3)-beta-D-glucan chain.	tmpzr1t_l9r_go_relaxed.owl	1,3-beta-glucan synthase complex|(1->3)-beta-glucan synthase complex													cellular_component											owl:Class	
GO:0034329	biolink:NamedThing	cell junction assembly	A cellular process that results in the aggregation, arrangement and bonding together of a set of components to form a cell junction.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1900485	biolink:NamedThing	positive regulation of protein targeting to vacuolar membrane	Any process that activates or increases the frequency, rate or extent of protein targeting to vacuolar membrane.	tmpzr1t_l9r_go_relaxed.owl	activation of protein targeting to vacuolar membrane|upregulation of protein targeting to vacuolar membrane|up-regulation of protein targeting to vacuolar membrane|up regulation of protein targeting to vacuolar membrane							al	2012-05-02T10:13:41Z					biological_process											owl:Class	
GO:1903494	biolink:NamedThing	response to dehydroepiandrosterone	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dehydroepiandrosterone stimulus.	tmpzr1t_l9r_go_relaxed.owl								mr	2014-09-25T17:01:18Z					biological_process											owl:Class	
GO:0019585	biolink:NamedThing	glucuronate metabolic process	The chemical reactions and pathways involving glucuronate, any salt or ester of glucuronic acid, the uronic acid formally derived from glucose by oxidation of the hydroxymethylene group at C-6 to a carboxyl group.	tmpzr1t_l9r_go_relaxed.owl	glucuronate metabolism				Wikipedia:Glucuronic_acid							GO:0019699		biological_process											owl:Class	
GO:0099165	biolink:NamedThing	postsynaptic specialization of symmetric synapse, intracellular component	A network of proteins adjacent to the postsynaptic membrane of a symmetric synapse. Its major components include that spatially and functionally organize neurotransmitter receptors in the adjacent membrane, such as anchoring and scaffolding molecules, signaling enzymes and cytoskeletal components.  This structure is not as thick or electron dense as the postsynaptic density found in asymmetric synapses.	tmpzr1t_l9r_go_relaxed.owl								dos	2017-09-10T11:54:15Z					cellular_component											owl:Class	
GO:1901285	biolink:NamedThing	5,6,7,8-tetrahydromethanopterin biosynthetic process	The chemical reactions and pathways resulting in the formation of 5,6,7,8-tetrahydromethanopterin.	tmpzr1t_l9r_go_relaxed.owl	5,6,7,8-tetrahydromethanopterin anabolism|5,6,7,8-tetrahydromethanopterin synthesis|5,6,7,8-tetrahydromethanopterin biosynthesis|5,6,7,8-tetrahydromethanopterin formation							yaf	2012-08-17T15:33:02Z					biological_process											owl:Class	
GO:0031258	biolink:NamedThing	lamellipodium membrane	The portion of the plasma membrane surrounding a lamellipodium.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:1902357	biolink:NamedThing	2-isopropylmalate(2-) transmembrane transport	The process in which 2-isopropylmalate(2-) is transported across a membrane.	tmpzr1t_l9r_go_relaxed.owl								dph	2013-08-14T14:43:49Z					biological_process											owl:Class	
GO:0140684	biolink:NamedThing	histone H3-tri/dimethyl-lysine-9 demethylase activity	Catalysis of the removal of a methyl group from a tri or a dimethyl-lysine residue at position 9 of the histone H3 protein. This is a dioxygenase reaction that is dependent on Fe(II) and 2-oxoglutarate.	tmpzr1t_l9r_go_relaxed.owl	histone H3K9me3 demethylase activity|histone H3K9me2 demethylase activity	https://github.com/geneontology/go-ontology/issues/21089			EC:1.14.11.66|RHEA:60200			pg	2021-07-09T06:03:55Z					molecular_function											owl:Class	
GO:0033339	biolink:NamedThing	pectoral fin development	The process whose specific outcome is the progression of the pectoral fin over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0033333	biolink:NamedThing	fin development	The process whose specific outcome is the progression of a fin over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0102941	biolink:NamedThing	3,5-dihydroxyanisole O-methyltransferase activity	Catalysis of the reaction: 3,5-dihydroxyanisole + S-adenosyl-L-methionine  = H+ + 3,5-dimethoxyphenol + S-adenosyl-L-homocysteine.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-9021									molecular_function											owl:Class	
GO:0150023	biolink:NamedThing	apical dendrite arborization	The process in which the anatomical structures of a dendritic tree are generated on the apical neuron side and organized into dendritic branches.	tmpzr1t_l9r_go_relaxed.owl								bc	2017-12-22T11:56:05Z					biological_process											owl:Class	
GO:0140059	biolink:NamedThing	dendrite arborization	The process in which the anatomical structures of a dendritic tree are generated and organized into dendritic branches.	tmpzr1t_l9r_go_relaxed.owl								pg	2017-07-12T15:12:07Z					biological_process											owl:Class	
GO:0007350	biolink:NamedThing	blastoderm segmentation	The hierarchical steps resulting in the progressive subdivision of the anterior/posterior axis of the embryo.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0018893	biolink:NamedThing	dibenzofuran metabolic process	The chemical reactions and pathways involving dibenzofuran, a substance composed of two benzene rings linked by one ether bond and one carbon-carbon bond. Dibenzofuran is a white crystalline solid created from the production of coal tar and used as an insecticide and an intermediate in the production of other chemicals.	tmpzr1t_l9r_go_relaxed.owl	dibenzofuran metabolism				UM-BBD_pathwayID:dbf									biological_process											owl:Class	
GO:0090318	biolink:NamedThing	regulation of chylomicron remodeling	Any process that modulates the rate, frequency, or extent of chylomicron remodeling. Chylomicron remodeling is the acquisition, loss or modification of a protein or lipid within a chylomicron, including the hydrolysis of triglyceride by lipoprotein lipase and the subsequent loss of free fatty acid.	tmpzr1t_l9r_go_relaxed.owl								tb	2010-04-30T10:09:08Z					biological_process											owl:Class	
GO:0048873	biolink:NamedThing	homeostasis of number of cells within a tissue	Any biological process involved in the maintenance of the steady-state number of cells within a population of cells in a tissue.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0002522	biolink:NamedThing	leukocyte migration involved in immune response	The movement of a leukocyte within or between different tissues and organs of the body as part of an immune response.	tmpzr1t_l9r_go_relaxed.owl	leukocyte trafficking during immune response|leucocyte migration during immune response|immune cell migration during immune response|leucocyte trafficking during immune response|immune cell trafficking during immune response													biological_process											owl:Class	
GO:0110138	biolink:NamedThing	positive regulation of imaginal disc-derived leg joint morphogenesis	Any process that activates or increases the frequency, rate or extent of imaginal disc-derived leg joint morphogenesis.	tmpzr1t_l9r_go_relaxed.owl								kmv	2019-02-12T15:37:05Z					biological_process											owl:Class	
GO:0097690	biolink:NamedThing	iron ion transmembrane transporter inhibitor activity	Binds to and stops, prevents, or reduces the activity of an iron ion transmembrane transporter.	tmpzr1t_l9r_go_relaxed.owl	iron channel inhibitor activity					An example of this is human hepcidin (UniProt symbol P81172), which regulates iron transport out of cells (see PMID:15514116).								molecular_function											owl:Class	
GO:0102611	biolink:NamedThing	(+)-secoisolariciresinol monoglucoside glucosyltransferase activity	Catalysis of the reaction: (+)-secoisolariciresinol monoglucoside + UDP-alpha-D-glucose <=> (+)-secoisolariciresinol diglucoside + UDP + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-15443									molecular_function											owl:Class	
GO:0005174	biolink:NamedThing	CD40 receptor binding	Binding to CD40, a receptor found on the surface of all B-lymphocytes.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0042771	biolink:NamedThing	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage, and ends when the execution phase of apoptosis is triggered.	tmpzr1t_l9r_go_relaxed.owl	DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis													biological_process											owl:Class	
GO:0008630	biolink:NamedThing	intrinsic apoptotic signaling pathway in response to DNA damage	A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced by the detection of DNA damage, and ends when the execution phase of apoptosis is triggered.	tmpzr1t_l9r_go_relaxed.owl	DNA damage response, signal transduction resulting in induction of apoptosis													biological_process											owl:Class	
GO:0060009	biolink:NamedThing	Sertoli cell development	The process whose specific outcome is the progression of a Sertoli cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a Sertoli cell fate.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0099019	biolink:NamedThing	maintenance of protein localization at growing cell tip	Any process in which localization of a protein is maintained at the growing cell tip.	tmpzr1t_l9r_go_relaxed.owl	maintenance of protein location at growing cell tip							dos	2016-06-30T15:17:41Z					biological_process											owl:Class	
GO:0030543	biolink:NamedThing	2-micrometer plasmid partitioning	The process in which copies of the 2-micrometer plasmid, found in fungi such as Saccharomyces, are distributed to daughter cells upon cell division.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0030541	biolink:NamedThing	plasmid partitioning	Any process in which plasmids are segregated or distributed into daughter cells upon cell division.	tmpzr1t_l9r_go_relaxed.owl												GO:0030542		biological_process											owl:Class	
GO:2001123	biolink:NamedThing	maltoheptaose catabolic process	The chemical reactions and pathways resulting in the breakdown of a maltoheptaose.	tmpzr1t_l9r_go_relaxed.owl	maltoheptaose catabolism							jl	2011-10-11T02:41:29Z					biological_process											owl:Class	
GO:2001122	biolink:NamedThing	maltoheptaose metabolic process	The chemical reactions and pathways involving a maltoheptaose.	tmpzr1t_l9r_go_relaxed.owl	maltoheptaose metabolism							jl	2011-10-11T02:41:26Z					biological_process											owl:Class	
GO:0031850	biolink:NamedThing	delta-type opioid receptor binding	Binding to a delta-type opioid receptor.	tmpzr1t_l9r_go_relaxed.owl	enkephalin receptor binding|delta-type opioid receptor ligand													molecular_function											owl:Class	
GO:0031628	biolink:NamedThing	opioid receptor binding	Binding to an opioid receptor.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1900176	biolink:NamedThing	negative regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry	Any process that stops, prevents or reduces the frequency, rate or extent of a nodal signaling pathway, where the nodal signaling pathway is involved in determination of left/right asymmetry in the lateral mesoderm.	tmpzr1t_l9r_go_relaxed.owl	downregulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry|inhibition of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry|down-regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry|negative regulation of nodal signalling pathway involved in determination of lateral mesoderm left/right asymmetry							bf	2012-03-09T10:39:14Z					biological_process											owl:Class	
GO:0070259	biolink:NamedThing	tyrosyl-DNA phosphodiesterase activity	Catalysis of the hydrolysis of phosphotyrosyl groups formed as covalent intermediates (in DNA backbone breakage) between a DNA topoisomerase and DNA.	tmpzr1t_l9r_go_relaxed.owl						See also the molecular function term 'DNA topoisomerase type I activity ; GO:0003917'.								molecular_function											owl:Class	
GO:0102593	biolink:NamedThing	UDP-glucose: N-methylanthranilate glucosyltransferase activity	Catalysis of the reaction: N-methylanthranilate + UDP-alpha-D-glucose = N-methylanthraniloyl-beta-D-glucopyranose + UDP.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-15371									molecular_function											owl:Class	
GO:1904367	biolink:NamedThing	positive regulation of chemokinesis	Any process that activates or increases the frequency, rate or extent of chemokinesis.	tmpzr1t_l9r_go_relaxed.owl	up regulation of chemokinesis|upregulation of chemokinesis|activation of chemokinesis|up-regulation of chemokinesis							sl	2015-06-15T22:44:18Z					biological_process											owl:Class	
GO:0035659	biolink:NamedThing	Wnt signaling pathway involved in wound healing, spreading of epidermal cells	The series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of a cell in the epidermis that contributes to the migration of an epidermal cell along or through a wound gap to reestablish a continuous epidermis.	tmpzr1t_l9r_go_relaxed.owl	Wnt receptor signalling pathway involved in wound healing, spreading of epidermal cells|Wnt receptor signaling pathway involved in wound healing, spreading of epidermal cells|Wnt-activated signaling pathway involved in wound healing, spreading of epidermal cells							bf	2011-01-28T11:34:02Z					biological_process											owl:Class	
GO:1901301	biolink:NamedThing	regulation of cargo loading into COPII-coated vesicle	Any process that modulates the frequency, rate or extent of cargo loading into COPII-coated vesicle.	tmpzr1t_l9r_go_relaxed.owl	regulation of cargo loading into COPII vesicle|regulation of COPII coat-cargo complex assembly|regulation of cargo selection into COPII-coated vesicle							bf	2012-08-21T13:03:00Z					biological_process											owl:Class	
GO:0009318	biolink:NamedThing	exodeoxyribonuclease VII complex	An enzyme complex that catalyzes exonucleolytic cleavage in either 5' to 3' or 3' to 5' direction to yield nucleoside 5'-phosphates; it prefers single-stranded DNA.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0032689	biolink:NamedThing	negative regulation of interferon-gamma production	Any process that stops, prevents, or reduces the frequency, rate, or extent of interferon-gamma production. Interferon-gamma is also known as type II interferon.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of interferon-gamma production|downregulation of interferon-gamma production|negative regulation of type II interferon production|inhibition of interferon-gamma production|negative regulation of interferon-gamma secretion|negative regulation of interferon-gamma biosynthetic process|down regulation of interferon-gamma production											GO:0045077|GO:1902714		biological_process											owl:Class	
GO:0043380	biolink:NamedThing	regulation of memory T cell differentiation	Any process that modulates the frequency, rate, or extent of memory T cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	regulation of memory T cell development|regulation of memory T-lymphocyte differentiation|regulation of memory T lymphocyte differentiation|regulation of memory T-cell differentiation					Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.								biological_process											owl:Class	
GO:0015308	biolink:NamedThing	amiloride:proton antiporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + amiloride(in) = H+(in) + amiloride(out).	tmpzr1t_l9r_go_relaxed.owl	amiloride:hydrogen antiporter activity													molecular_function											owl:Class	
GO:0043994	biolink:NamedThing	histone acetyltransferase activity (H3-K23 specific)	Catalysis of the reaction: acetyl-CoA + histone H3 L-lysine (position 23) = CoA + histone H3 N6-acetyl-L-lysine (position 23).	tmpzr1t_l9r_go_relaxed.owl	histone lysine N-acetyltransferase activity (H3-K23 specific)													molecular_function											owl:Class	
GO:0048284	biolink:NamedThing	organelle fusion	The creation of a single organelle from two or more organelles.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1904205	biolink:NamedThing	negative regulation of skeletal muscle hypertrophy	Any process that stops, prevents or reduces the frequency, rate or extent of skeletal muscle hypertrophy.	tmpzr1t_l9r_go_relaxed.owl	downregulation of skeletal muscle hypertrophy|down-regulation of skeletal muscle hypertrophy|inhibition of skeletal muscle hypertrophy|down regulation of skeletal muscle hypertrophy							sl	2015-05-08T17:38:19Z					biological_process											owl:Class	
GO:1904204	biolink:NamedThing	regulation of skeletal muscle hypertrophy	Any process that modulates the frequency, rate or extent of skeletal muscle hypertrophy.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-05-08T17:38:13Z					biological_process											owl:Class	
GO:0018858	biolink:NamedThing	benzoate-CoA ligase activity	Catalysis of the reaction: ATP + benzoate + CoA = AMP + benzoyl-CoA + diphosphate.	tmpzr1t_l9r_go_relaxed.owl	benzoate:CoA ligase (AMP-forming)|benzoate-coenzyme A ligase activity|benzoyl-coenzyme A synthetase activity|benzoyl CoA synthetase (AMP forming)				MetaCyc:BENZOATE--COA-LIGASE-RXN|RHEA:10132|KEGG_REACTION:R01422|UM-BBD_reactionID:r0189|EC:6.2.1.25									molecular_function											owl:Class	
GO:0032891	biolink:NamedThing	negative regulation of organic acid transport	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of organic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	downregulation of organic acid transport|inhibition of organic acid transport|down-regulation of organic acid transport|down regulation of organic acid transport													biological_process											owl:Class	
GO:1903665	biolink:NamedThing	negative regulation of asexual reproduction	Any process that stops, prevents or reduces the frequency, rate or extent of asexual reproduction.	tmpzr1t_l9r_go_relaxed.owl	inhibition of asexual reproduction|downregulation of asexual reproduction|down regulation of asexual reproduction|down-regulation of asexual reproduction							pf	2014-11-26T21:13:32Z					biological_process											owl:Class	
GO:1903628	biolink:NamedThing	negative regulation of dUTP diphosphatase activity	Any process that stops, prevents or reduces the frequency, rate or extent of dUTP diphosphatase activity.	tmpzr1t_l9r_go_relaxed.owl	downregulation of dUTP pyrophosphatase activity|inhibition of dUTP nucleotidohydrolase activity|negative regulation of dUTP nucleotidohydrolase activity|down regulation of deoxyuridine-triphosphatase activity|negative regulation of desoxyuridine 5'-triphosphatase activity|inhibition of dUTPase activity|inhibition of deoxyuridine-triphosphatase activity|down-regulation of desoxyuridine 5'-triphosphate nucleotidohydrolase activity|negative regulation of dUTP pyrophosphatase activity|down-regulation of dUTP diphosphatase activity|down-regulation of deoxyuridine-triphosphatase activity|down regulation of dUTP diphosphatase activity|down regulation of dUTP nucleotidohydrolase activity|negative regulation of dUTPase activity|down-regulation of dUTP nucleotidohydrolase activity|downregulation of dUTP diphosphatase activity|down-regulation of desoxyuridine 5'-triphosphatase activity|negative regulation of deoxyuridine-triphosphatase activity|down regulation of desoxyuridine 5'-triphosphate nucleotidohydrolase activity|downregulation of dUTPase activity|down regulation of desoxyuridine 5'-triphosphatase activity|downregulation of dUTP nucleotidohydrolase activity|inhibition of desoxyuridine 5'-triphosphatase activity|downregulation of deoxyuridine-triphosphatase activity|inhibition of dUTP diphosphatase activity|inhibition of desoxyuridine 5'-triphosphate nucleotidohydrolase activity|downregulation of desoxyuridine 5'-triphosphate nucleotidohydrolase activity|downregulation of desoxyuridine 5'-triphosphatase activity|down-regulation of dUTPase activity|down regulation of dUTP pyrophosphatase activity|down regulation of dUTPase activity|down-regulation of dUTP pyrophosphatase activity|inhibition of dUTP pyrophosphatase activity|negative regulation of desoxyuridine 5'-triphosphate nucleotidohydrolase activity							sl	2014-11-20T00:00:44Z					biological_process											owl:Class	
GO:1904374	biolink:NamedThing	cellular response to kainic acid	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a kainic acid stimulus.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-06-18T22:42:58Z					biological_process											owl:Class	
GO:0015229	biolink:NamedThing	L-ascorbic acid transmembrane transporter activity	Enables the transfer of L-ascorbate from one side of a membrane to the other. L-ascorbate, (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate, is vitamin C and has co-factor and anti-oxidant activities in many species.	tmpzr1t_l9r_go_relaxed.owl	L-ascorbate transporter activity|vitamin C transporter activity				Reactome:R-HSA-198870									molecular_function											owl:Class	
GO:0009907	biolink:NamedThing	response to photoperiod, red light	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a red light photoperiod stimulus. Red light is electromagnetic radiation of wavelength of 580-700nm.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0010329	biolink:NamedThing	auxin efflux transmembrane transporter activity	Enables the transfer of auxin, from one side of a membrane to the other, out of a cell.	tmpzr1t_l9r_go_relaxed.owl	auxin efflux facilitator|auxin efflux carrier													molecular_function											owl:Class	
GO:0010929	biolink:NamedThing	positive regulation of auxin mediated signaling pathway	Any process that increases the rate, frequency or extent of auxin mediated signaling pathway. Auxin mediated signaling pathway is the series of molecular signals generated in response to detection of auxin.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of auxin mediated signalling pathway													biological_process											owl:Class	
GO:0046921	biolink:NamedThing	alpha-(1->6)-fucosyltransferase activity	Catalysis of the transfer of an L-fucosyl group from GDP-beta-L-fucose to an acceptor molecule to form an alpha-(1->6) linkage.	tmpzr1t_l9r_go_relaxed.owl	alpha-(1,6)-fucosyltransferase activity|alpha-1,6-fucosyltransferase activity|alpha(1,6)-fucosyltransferase activity													molecular_function											owl:Class	
GO:0008417	biolink:NamedThing	fucosyltransferase activity	Catalysis of the transfer of a fucosyl group to an acceptor molecule, typically another carbohydrate or a lipid.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-9033949									molecular_function											owl:Class	
GO:1902245	biolink:NamedThing	cis-abienol catabolic process	The chemical reactions and pathways resulting in the breakdown of cis-abienol.	tmpzr1t_l9r_go_relaxed.owl	cis-abienol catabolism|cis-abienol degradation|cis-abienol breakdown							ms	2013-06-20T09:09:57Z					biological_process											owl:Class	
GO:0022890	biolink:NamedThing	inorganic cation transmembrane transporter activity	Enables the transfer of inorganic cations from one side of a membrane to the other. Inorganic cations are atoms or small molecules with a positive charge that do not contain carbon in covalent linkage.	tmpzr1t_l9r_go_relaxed.owl	trivalent inorganic cation transmembrane transporter activity|di-, tri-valent inorganic cation transmembrane transporter activity|monovalent inorganic cation transmembrane transporter activity|divalent inorganic cation transmembrane transporter activity											GO:0015082|GO:0015077|GO:0072510|GO:0072509		molecular_function											owl:Class	
GO:1990677	biolink:NamedThing	mitochondrial inner membrane assembly complex	A protein complex that promotes the biogenesis of mitochondrial F1Fo-ATP synthase by facilitating assembly of the peripheral stalk. Loss of INAC function causes dissociation of the F1-domain from the membrane-integral Fo-portion.	tmpzr1t_l9r_go_relaxed.owl	mitochondrion inner membrane assembly complex|inner membrane assembly complex|INAC complex					An example of this is INA22 in Saccharomyces cerevisiae (P40576) in PMID:24942160 (inferred from direct assay/mutant phenotype/etc.).		bhm	2015-03-02T13:14:52Z					cellular_component											owl:Class	
GO:0031315	biolink:NamedThing	extrinsic component of mitochondrial outer membrane	The component of a mitochondrial outer membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.	tmpzr1t_l9r_go_relaxed.owl	extrinsic to mitochondrial outer membrane													cellular_component											owl:Class	
GO:0051057	biolink:NamedThing	positive regulation of small GTPase mediated signal transduction	Any process that activates or increases the frequency, rate or extent of small GTPase mediated signal transduction.	tmpzr1t_l9r_go_relaxed.owl	up regulation of small GTPase mediated signal transduction|activation of small GTPase mediated signal transduction|up-regulation of small GTPase mediated signal transduction|positive regulation of small GTPase-mediated signal transduction|stimulation of small GTPase mediated signal transduction|upregulation of small GTPase mediated signal transduction													biological_process											owl:Class	
GO:0042937	biolink:NamedThing	tripeptide transmembrane transporter activity	Enables the transfer of a tripeptide, a compound containing three amino acids linked together by peptide bonds, from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	tripeptide transporter activity													molecular_function											owl:Class	
GO:0046418	biolink:NamedThing	nopaline metabolic process	The chemical reactions and pathways involving nopaline, (N-(I-carboxy-4-guanidinobutyl)glutamic acid), a rare amino-acid derivative.	tmpzr1t_l9r_go_relaxed.owl	nopaline metabolism													biological_process											owl:Class	
GO:0036417	biolink:NamedThing	tRNA destabilization	Any process that decreases the stability of a tRNA molecule, making it more vulnerable to degradative processes.	tmpzr1t_l9r_go_relaxed.owl								bf	2013-08-22T15:43:13Z					biological_process											owl:Class	
GO:1902372	biolink:NamedThing	positive regulation of tRNA catabolic process	Any process that activates or increases the frequency, rate or extent of tRNA catabolic process.	tmpzr1t_l9r_go_relaxed.owl	activation of tRNA catabolic process|positive regulation of tRNA catabolism|up regulation of tRNA catabolism|up-regulation of tRNA breakdown|upregulation of tRNA breakdown|upregulation of tRNA degradation|up-regulation of tRNA degradation|upregulation of tRNA catabolic process|up regulation of tRNA breakdown|up regulation of tRNA catabolic process|activation of tRNA degradation|up-regulation of tRNA catabolic process|activation of tRNA catabolism|positive regulation of tRNA breakdown|activation of tRNA breakdown|upregulation of tRNA catabolism|up regulation of tRNA degradation|positive regulation of tRNA degradation|up-regulation of tRNA catabolism							bf	2013-08-22T15:08:29Z					biological_process											owl:Class	
GO:0002006	biolink:NamedThing	vasoconstriction by vasopressin involved in systemic arterial blood pressure control	The decrease in blood vessel diameter as a result of the release of vasopressin into the blood stream.	tmpzr1t_l9r_go_relaxed.owl	vasopressin mediated vasoconstriction involved in systemic arterial blood pressure control													biological_process											owl:Class	
GO:2000386	biolink:NamedThing	positive regulation of ovarian follicle development	Any process that activates or increases the frequency, rate or extent of ovarian follicle development.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of follicular phase							yaf	2011-02-16T02:21:21Z					biological_process											owl:Class	
GO:0045849	biolink:NamedThing	negative regulation of nurse cell apoptotic process	Any process that stops, prevents, or reduces the frequency, rate or extent of nurse cell apoptotic process.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of nurse cell apoptosis|down regulation of nurse cell apoptosis|downregulation of nurse cell apoptosis|down-regulation of nurse cell apoptosis|inhibition of nurse cell apoptosis													biological_process											owl:Class	
GO:1904746	biolink:NamedThing	negative regulation of apoptotic process involved in development	Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic process involved in development.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of programmed cell death by apoptosis involved in anatomical structure development|inhibition of apoptotic programmed cell death involved in development of an anatomical structure|inhibition of activation of apoptosis involved in anatomical structure development|down regulation of apoptotic process involved in anatomical structure development|inhibition of apoptosis signaling involved in development of an anatomical structure|down regulation of apoptotic program involved in anatomical structure development|down regulation of apoptotic programmed cell death involved in development of an anatomical structure|negative regulation of apoptosis involved in development of an anatomical structure|inhibition of signaling (initiator) caspase activity involved in development of an anatomical structure|negative regulation of activation of apoptosis involved in anatomical structure development|inhibition of apoptosis activator activity involved in development of an anatomical structure|inhibition of apoptotic cell death involved in anatomical structure development|down-regulation of apoptosis signaling involved in development of an anatomical structure|down regulation of induction of apoptosis involved in development of an anatomical structure|inhibition of activation of apoptosis involved in development of an anatomical structure|negative regulation of induction of apoptosis by p53 involved in development of an anatomical structure|down-regulation of apoptotic cell death involved in development of an anatomical structure|inhibition of type I programmed cell death involved in development of an anatomical structure|downregulation of apoptotic program involved in anatomical structure development|down regulation of apoptotic cell death involved in development of an anatomical structure|down regulation of apoptosis activator activity involved in anatomical structure development|inhibition of apoptotic program involved in development of an anatomical structure|inhibition of induction of apoptosis by p53 involved in development of an anatomical structure|negative regulation of commitment to apoptosis involved in development of an anatomical structure|down-regulation of induction of apoptosis involved in anatomical structure development|inhibition of apoptosis activator activity involved in anatomical structure development|downregulation of apoptosis involved in anatomical structure development|down regulation of activation of apoptosis involved in anatomical structure development|inhibition of programmed cell death by apoptosis involved in anatomical structure development|downregulation of apoptotic process involved in development|downregulation of type I programmed cell death involved in development of an anatomical structure|downregulation of apoptosis activator activity involved in anatomical structure development|downregulation of signaling (initiator) caspase activity involved in development of an anatomical structure|down-regulation of apoptosis involved in anatomical structure development|down-regulation of apoptosis activator activity involved in development of an anatomical structure|inhibition of apoptotic process involved in development|down regulation of apoptotic process involved in development of an anatomical structure|negative regulation of activation of apoptosis involved in development of an anatomical structure|down-regulation of signaling (initiator) caspase activity involved in development of an anatomical structure|negative regulation of apoptotic programmed cell death involved in development of an anatomical structure|downregulation of commitment to apoptosis involved in development of an anatomical structure|downregulation of signaling (initiator) caspase activity involved in anatomical structure development|down regulation of apoptosis involved in development of an anatomical structure|negative regulation of programmed cell death by apoptosis involved in anatomical structure development|downregulation of apoptotic programmed cell death involved in development of an anatomical structure|downregulation of apoptosis involved in development of an anatomical structure|down regulation of signaling (initiator) caspase activity involved in anatomical structure development|down regulation of programmed cell death by apoptosis involved in anatomical structure development|down-regulation of induction of apoptosis by p53 involved in development of an anatomical structure|down regulation of apoptosis activator activity involved in development of an anatomical structure|negative regulation of signaling (initiator) caspase activity involved in anatomical structure development|down-regulation of apoptotic process involved in development|negative regulation of apoptotic process involved in anatomical structure development|down-regulation of apoptosis signaling involved in anatomical structure development|inhibition of apoptotic cell death involved in development of an anatomical structure|downregulation of induction of apoptosis involved in anatomical structure development|down-regulation of activation of apoptosis involved in development of an anatomical structure|downregulation of apoptotic cell death involved in development of an anatomical structure|down regulation of programmed cell death by apoptosis involved in development of an anatomical structure|down regulation of signaling (initiator) caspase activity involved in development of an anatomical structure|down regulation of apoptotic program involved in development of an anatomical structure|negative regulation of apoptotic program involved in anatomical structure development|down-regulation of commitment to apoptosis involved in development of an anatomical structure|down regulation of apoptosis signaling involved in anatomical structure development|down regulation of induction of apoptosis by p53 involved in anatomical structure development|down regulation of type I programmed cell death involved in anatomical structure development|down-regulation of induction of apoptosis involved in development of an anatomical structure|negative regulation of apoptotic cell death involved in anatomical structure development|down-regulation of apoptotic programmed cell death involved in development of an anatomical structure|downregulation of activation of apoptosis involved in anatomical structure development|inhibition of apoptosis involved in anatomical structure development|inhibition of apoptosis involved in development of an anatomical structure|down-regulation of type I programmed cell death involved in development of an anatomical structure|inhibition of commitment to apoptosis involved in development of an anatomical structure|downregulation of programmed cell death by apoptosis involved in anatomical structure development|inhibition of apoptotic programmed cell death involved in anatomical structure development|down regulation of apoptotic process involved in development|negative regulation of induction of apoptosis involved in development of an anatomical structure|inhibition of apoptosis signaling involved in anatomical structure development|inhibition of induction of apoptosis involved in anatomical structure development|inhibition of apoptotic process involved in anatomical structure development|downregulation of activation of apoptosis involved in development of an anatomical structure|down-regulation of type I programmed cell death involved in anatomical structure development|negative regulation of apoptotic programmed cell death involved in anatomical structure development|downregulation of type I programmed cell death involved in anatomical structure development|downregulation of induction of apoptosis involved in development of an anatomical structure|negative regulation of apoptotic cell death involved in development of an anatomical structure|down-regulation of apoptotic process involved in development of an anatomical structure|negative regulation of apoptosis involved in anatomical structure development|down-regulation of programmed cell death by apoptosis involved in development of an anatomical structure|negative regulation of signaling (initiator) caspase activity involved in development of an anatomical structure|down regulation of induction of apoptosis involved in anatomical structure development|down-regulation of apoptotic program involved in development of an anatomical structure|inhibition of induction of apoptosis involved in development of an anatomical structure|negative regulation of apoptosis signaling involved in development of an anatomical structure|inhibition of apoptotic program involved in anatomical structure development|negative regulation of type I programmed cell death involved in development of an anatomical structure|down regulation of apoptotic cell death involved in anatomical structure development|down regulation of apoptotic programmed cell death involved in anatomical structure development|down-regulation of activation of apoptosis involved in anatomical structure development|down regulation of commitment to apoptosis involved in development of an anatomical structure|down regulation of apoptosis involved in anatomical structure development|inhibition of apoptotic process involved in development of an anatomical structure|inhibition of signaling (initiator) caspase activity involved in anatomical structure development|down-regulation of apoptotic process involved in anatomical structure development|negative regulation of induction of apoptosis by p53 involved in anatomical structure development|downregulation of apoptotic cell death involved in anatomical structure development|downregulation of programmed cell death by apoptosis involved in development of an anatomical structure|negative regulation of type I programmed cell death involved in anatomical structure development|inhibition of induction of apoptosis by p53 involved in anatomical structure development|down-regulation of apoptosis involved in development of an anatomical structure|down regulation of apoptosis signaling involved in development of an anatomical structure|negative regulation of apoptosis activator activity involved in anatomical structure development|downregulation of apoptotic program involved in development of an anatomical structure|downregulation of apoptotic process involved in anatomical structure development|negative regulation of commitment to apoptosis involved in anatomical structure development|inhibition of type I programmed cell death involved in anatomical structure development|downregulation of apoptosis signaling involved in anatomical structure development|inhibition of programmed cell death by apoptosis involved in development of an anatomical structure|down regulation of commitment to apoptosis involved in anatomical structure development|down-regulation of apoptosis activator activity involved in anatomical structure development|down regulation of induction of apoptosis by p53 involved in development of an anatomical structure|downregulation of commitment to apoptosis involved in anatomical structure development|downregulation of apoptosis activator activity involved in development of an anatomical structure|negative regulation of induction of apoptosis involved in anatomical structure development|negative regulation of apoptosis signaling involved in anatomical structure development|negative regulation of apoptotic program involved in development of an anatomical structure|down-regulation of apoptotic program involved in anatomical structure development|downregulation of apoptotic programmed cell death involved in anatomical structure development|down regulation of activation of apoptosis involved in development of an anatomical structure|downregulation of apoptosis signaling involved in development of an anatomical structure|negative regulation of programmed cell death by apoptosis involved in development of an anatomical structure|downregulation of induction of apoptosis by p53 involved in development of an anatomical structure|downregulation of apoptotic process involved in development of an anatomical structure|down-regulation of apoptotic programmed cell death involved in anatomical structure development|down-regulation of induction of apoptosis by p53 involved in anatomical structure development|down-regulation of commitment to apoptosis involved in anatomical structure development|negative regulation of apoptosis activator activity involved in development of an anatomical structure|down-regulation of signaling (initiator) caspase activity involved in anatomical structure development|inhibition of commitment to apoptosis involved in anatomical structure development|down-regulation of apoptotic cell death involved in anatomical structure development|down regulation of type I programmed cell death involved in development of an anatomical structure|downregulation of induction of apoptosis by p53 involved in anatomical structure development|negative regulation of apoptotic process involved in development of an anatomical structure					U4PR86 in PMID:22801495 inferred from mutant phenotype		es	2015-10-19T14:12:27Z					biological_process											owl:Class	
GO:1903928	biolink:NamedThing	cellular response to cyanide	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cyanide stimulus.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-02-11T19:04:28Z					biological_process											owl:Class	
GO:1903927	biolink:NamedThing	response to cyanide	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cyanide stimulus.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-02-11T19:04:19Z					biological_process											owl:Class	
GO:0021899	biolink:NamedThing	fibroblast growth factor receptor signaling pathway involved in forebrain neuron fate commitment	The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands that contributes to the commitment of a neuroblast to a neuronal fate. The neuron will reside in the forebrain.	tmpzr1t_l9r_go_relaxed.owl	fibroblast growth factor receptor signalling pathway involved in forebrain neuron fate commitment													biological_process											owl:Class	
GO:0033259	biolink:NamedThing	plastid DNA replication	The process in which new strands of DNA are synthesized in a plastid.	tmpzr1t_l9r_go_relaxed.owl	replication of plastid DNA|plastid DNA synthesis													biological_process											owl:Class	
GO:0033258	biolink:NamedThing	plastid DNA metabolic process	The chemical reactions and pathways involving plastid DNA.	tmpzr1t_l9r_go_relaxed.owl	plastid DNA metabolism													biological_process											owl:Class	
GO:0019700	biolink:NamedThing	organic phosphonate catabolic process	The chemical reactions and pathways resulting in the breakdown of phosphonates, any organic compound containing one or more C-PO(OH)2 or C-PO(OR)2 (with R=alkyl, aryl) groups. Catabolism of phosphonic acid itself, an inorganic compound without the biochemically relevant C-P bond, is not included.	tmpzr1t_l9r_go_relaxed.owl	organophosphonate catabolic process|phosphonate catabolism|phosphonate degradation|phosphonate breakdown													biological_process											owl:Class	
GO:0019634	biolink:NamedThing	organic phosphonate metabolic process	The chemical reactions and pathways involving phosphonates, any organic compounds containing one or more C-PO(OH)2 or C-PO(OR)2 (with R=alkyl, aryl) groups. Metabolism of phosphonic acid itself, an inorganic compound without the biochemically relevant C-P bond, is not included.	tmpzr1t_l9r_go_relaxed.owl	phosphonate metabolism|organophosphonate metabolic process													biological_process											owl:Class	
GO:0019283	biolink:NamedThing	L-methionine biosynthetic process from O-phospho-L-homoserine and cystathionine	The chemical reactions and pathways resulting in the formation of L-methionine from other compounds, including O-phospho-L-homoserine and cystathionine.	tmpzr1t_l9r_go_relaxed.owl	methionine biosynthetic process from O-phospho-L-homoserine and cystathionine|L-methionine formation from O-phospho-L-homoserine and cystathionine|L-methionine synthesis from O-phospho-L-homoserine and cystathionine|L-methionine anabolism from O-phospho-L-homoserine and cystathionine													biological_process											owl:Class	
GO:0071366	biolink:NamedThing	cellular response to indolebutyric acid stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an indolebutyric acid stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to indole-3-butyric acid stimulus|cellular response to IBA stimulus							mah	2009-12-11T03:12:14Z					biological_process											owl:Class	
GO:0034592	biolink:NamedThing	synaptic vesicle lumen	The volume enclosed by the synaptic vesicle membrane.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:1900736	biolink:NamedThing	regulation of phospholipase C-activating G protein-coupled receptor signaling pathway	Any process that modulates the frequency, rate or extent of phospholipase C-activating G protein-coupled receptor signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	regulation of activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger|regulation of G-protein signalling, coupled to IP3 second messenger (phospholipase C activating)|regulation of G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)|regulation of G-protein coupled receptor signaling pathway coupled to IP3 second messenger|regulation of G protein signaling, coupled to IP3 second messenger (phospholipase C activating)|regulation of PLC-activating GPCR signaling pathway|regulation of phospholipase C-activating dopamine receptor signaling pathway|regulation of G protein signalling, coupled to IP3 second messenger (phospholipase C activating)|regulation of phospholipase C-activating G-protein coupled receptor signaling pathway							rl	2012-05-28T10:07:27Z					biological_process											owl:Class	
GO:0070652	biolink:NamedThing	HAUS complex	A protein complex that localizes to interphase centrosomes and to mitotic spindle tubules and regulates mitotic spindle assembly and centrosome integrity; in human, the complex consists of eight subunits, some of which are homologous to subunits of the Drosophila Augmin complex.	tmpzr1t_l9r_go_relaxed.owl	HAUS augmin complex							mah	2009-05-28T03:21:01Z					cellular_component											owl:Class	
GO:0046646	biolink:NamedThing	regulation of gamma-delta T cell proliferation	Any process that modulates the frequency, rate or extent of gamma-delta T cell proliferation.	tmpzr1t_l9r_go_relaxed.owl	regulation of gamma-delta T lymphocyte proliferation|regulation of gamma-delta T-lymphocyte proliferation|regulation of gamma-delta T-cell proliferation													biological_process											owl:Class	
GO:0086100	biolink:NamedThing	endothelin receptor signaling pathway	A series of molecular signals initiated by an endothelin receptor binding to one of its physiological ligands, and proceeding with the activated receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. Ends with regulation of a downstream cellular process, e.g. transcription.	tmpzr1t_l9r_go_relaxed.owl	endothelin signaling pathway							bf						biological_process											owl:Class	
GO:0022623	biolink:NamedThing	proteasome-activating nucleotidase complex	A homohexameric complex that recognizes and unfolds core proteasome substrate proteins, and translocates them to the core complex in an ATP dependent manner.	tmpzr1t_l9r_go_relaxed.owl	PAN													cellular_component											owl:Class	
GO:0071795	biolink:NamedThing	K11-linked polyubiquitin modification-dependent protein binding	Binding to a protein upon poly-ubiquitination formed by linkages between lysine residues at position 11 in the target protein.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-09-02T02:11:41Z					molecular_function											owl:Class	
GO:0031593	biolink:NamedThing	polyubiquitin modification-dependent protein binding	Binding to a protein upon poly-ubiquitination of the target protein.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0097205	biolink:NamedThing	renal filtration	A renal system process in which fluid circulating through the body is filtered through a barrier system.	tmpzr1t_l9r_go_relaxed.owl								pr	2012-01-03T03:10:17Z					biological_process											owl:Class	
GO:0019534	biolink:NamedThing	toxin transmembrane transporter activity	Enables the transfer of a toxin from one side of a membrane to the other. A toxin is a poisonous compound (typically a protein) that is produced by cells or organisms and that can cause disease when introduced into the body or tissues of an organism.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1905184	biolink:NamedThing	positive regulation of protein serine/threonine phosphatase activity	Any process that activates or increases the frequency, rate or extent of protein serine/threonine phosphatase activity.	tmpzr1t_l9r_go_relaxed.owl	activation of serine/threonine specific protein phosphatase activity|up-regulation of protein serine/threonine phosphatase activity|upregulation of protein serine/threonine phosphatase activity|up regulation of serine/threonine specific protein phosphatase activity|up regulation of protein serine/threonine phosphatase activity|upregulation of serine/threonine specific protein phosphatase activity|activation of protein serine/threonine phosphatase activity|positive regulation of serine/threonine specific protein phosphatase activity|up-regulation of serine/threonine specific protein phosphatase activity							mah	2016-05-10T15:28:13Z					biological_process											owl:Class	
GO:0032516	biolink:NamedThing	positive regulation of phosphoprotein phosphatase activity	Any process that activates or increases the activity of a phosphoprotein phosphatase.	tmpzr1t_l9r_go_relaxed.owl	upregulation of protein phosphatase type 2A activity|activation of protein phosphatase type 2A activity|upregulation of phosphoprotein phosphatase activity|upregulation of protein phosphatase type 2B activity|stimulation of protein phosphatase 2 activity|stimulation of phosphoprotein phosphatase activity|activation of phosphoprotein phosphatase activity|calcineurin activation|upregulation of protein phosphatase 2 activity|activation of protein phosphatase 3 activity|positive regulation of protein phosphatase 3 activity|activation of protein phosphatase type 2B activity|up regulation of protein phosphatase 3 activity|positive regulation of protein phosphatase 2 activity|up-regulation of protein phosphatase type 2A activity|up regulation of calcineurin activity|stimulation of protein phosphatase type 2A activity|activation of calcineurin activity|positive regulation of protein phosphatase type 2A activity|up-regulation of protein phosphatase 2 activity|up regulation of protein phosphatase type 2A activity|positive regulation of calcineurin activity|stimulation of protein phosphatase type 2B activity|up regulation of phosphoprotein phosphatase activity|positive regulation of protein phosphatase type 2B activity|up regulation of protein phosphatase 2 activity|up regulation of protein phosphatase type 2B activity|up-regulation of phosphoprotein phosphatase activity|up-regulation of protein phosphatase type 2B activity											GO:0032514|GO:0034049		biological_process											owl:Class	
GO:2000229	biolink:NamedThing	regulation of pancreatic stellate cell proliferation	Any process that modulates the frequency, rate or extent of pancreatic stellate cell proliferation.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-11-09T03:45:18Z					biological_process											owl:Class	
GO:0010164	biolink:NamedThing	response to cesium ion	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cesium stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to cesium													biological_process											owl:Class	
GO:1905191	biolink:NamedThing	positive regulation of metaphase/anaphase transition of meiosis II	Any process that activates or increases the frequency, rate or extent of metaphase/anaphase transition of meiosis II.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of meiosis II metaphase/anaphase transition							vw	2016-05-10T16:47:05Z					biological_process											owl:Class	
GO:0001586	biolink:NamedThing	Gi/o-coupled serotonin receptor activity	Combining with serotonin and transmitting the signal across the membrane by activation of the Gi/o subunit of an associated cytoplasmic heterotrimeric G protein complex. The Gi/o subunit subsequently inhibits adenylate cyclase and results in a decrease in cyclic AMP (cAMP) levels.	tmpzr1t_l9r_go_relaxed.owl	5-HT1 receptor activity|serotonin receptor activity, coupled via Gi/o													molecular_function											owl:Class	
GO:0004993	biolink:NamedThing	G protein-coupled serotonin receptor activity	Combining with the biogenic amine serotonin and transmitting the signal across the membrane by activating an associated G-protein. Serotonin (5-hydroxytryptamine) is a neurotransmitter and hormone found in vertebrates and invertebrates.	tmpzr1t_l9r_go_relaxed.owl	5-HT receptor|5-hydroxytryptamine receptor|G-protein coupled serotonin receptor activity|G protein coupled serotonin receptor activity	https://github.com/geneontology/go-ontology/issues/12942			Wikipedia:5-HT_receptor							GO:0016609|GO:0001585		molecular_function											owl:Class	
GO:0005352	biolink:NamedThing	alpha-glucoside:proton symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: alpha-glucoside(out) + H+(out) = alpha-glucoside(in) + H+(in). Alpha-glucosides include trehalose, maltose, turanose, isomaltose, alpha-methylglucoside, maltotriose, palatinose, trehalose and melezitose.	tmpzr1t_l9r_go_relaxed.owl	alpha-glucoside:hydrogen symporter activity|general alpha-glucoside:proton symporter activity|general alpha-glucoside transporter activity|general alpha-glucoside:hydrogen symporter activity													molecular_function											owl:Class	
GO:0047004	biolink:NamedThing	UDP-N-acetylglucosamine 6-dehydrogenase activity	Catalysis of the reaction: H(2)O + 2 NAD(+) + UDP-N-acetyl-alpha-D-glucosamine = 3 H(+) + 2 NADH + UDP-N-acetyl-2-amino-2-deoxy-D-glucuronate.	tmpzr1t_l9r_go_relaxed.owl	UDP-2-acetamido-2-deoxy-D-glucose:NAD oxidoreductase activity|UDP-GLcNAc dehydrogenase activity|UDP-N-acetyl-D-glucosamine:NAD+ 6-oxidoreductase activity|uridine diphosphoacetylglucosamine dehydrogenase activity|UDPacetylglucosamine dehydrogenase activity				KEGG_REACTION:R00421|EC:1.1.1.136|RHEA:13325|MetaCyc:1.1.1.136-RXN									molecular_function											owl:Class	
GO:0099568	biolink:NamedThing	cytoplasmic region	Any (proper) part of the cytoplasm of a single cell of sufficient size to still be considered cytoplasm.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0072252	biolink:NamedThing	metanephric juxtaglomerulus cell development	The process whose specific outcome is the progression of a metanephric juxtaglomerulus cell over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-03-19T03:55:31Z					biological_process											owl:Class	
GO:0072142	biolink:NamedThing	juxtaglomerulus cell development	The process whose specific outcome is the progression of a juxtaglomerulus cell over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-02-24T01:42:53Z					biological_process											owl:Class	
GO:2001258	biolink:NamedThing	negative regulation of cation channel activity	Any process that stops, prevents or reduces the frequency, rate or extent of cation channel activity.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of nonselective cation channel activity|negative regulation of cation diffusion facilitator activity							vk	2011-12-07T07:14:51Z					biological_process											owl:Class	
GO:0018685	biolink:NamedThing	alkane 1-monooxygenase activity	Catalysis of the reaction: octane + reduced rubredoxin + O2 = 1-octanol + oxidized rubredoxin + H2O.	tmpzr1t_l9r_go_relaxed.owl	1-hydroxylase activity|lauric acid omega-hydroxylase activity|alkane hydroxylase activity|alkane 1-hydroxylase activity|fatty acid (omega-1)-hydroxylase activity|alkane monooxygenase activity|fatty acid omega-hydroxylase activity|omega-hydroxylase activity|alkane,reduced-rubredoxin:oxygen 1-oxidoreductase activity				UM-BBD_enzymeID:e0022|EC:1.14.15.3|MetaCyc:ALKANE-1-MONOOXYGENASE-RXN|RHEA:19341							GO:0008393		molecular_function											owl:Class	
GO:0015729	biolink:NamedThing	oxaloacetate transport	The directed movement of oxaloacetate, the anion of oxobutanedioic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0070695	biolink:NamedThing	FHF complex	A protein complex that is composed of AKTIP/FTS, FAM160A2/p107FHIP, and one or more members of the Hook family of proteins, HOOK1, HOOK2, and HOOK3. The complex is thought to promote vesicle trafficking and/or fusion, and associates with the homotypic vesicular sorting complex (the HOPS complex).	tmpzr1t_l9r_go_relaxed.owl						Note that the gene/protein name 'APC' should not be confused with the abbreviation for 'anaphase promoting complex'.		mah	2009-06-04T03:17:29Z					cellular_component											owl:Class	
GO:0003297	biolink:NamedThing	heart wedging	The morphogenetic process in which the aorta inserts between the atrioventricular valves, contributing to the shaping of the heart.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-10-22T08:52:58Z					biological_process											owl:Class	
GO:0050002	biolink:NamedThing	D-proline reductase (dithiol) activity	Catalysis of the reaction: lipoate + 5-aminopentanoate = dihydrolipoate + D-proline.	tmpzr1t_l9r_go_relaxed.owl	5-aminopentanoate:lipoate oxidoreductase (cyclizing)				EC:1.21.4.1|RHEA:12737|MetaCyc:1.21.4.1-RXN	Note that this function was formerly EC:1.4.4.1.								molecular_function											owl:Class	
GO:0002648	biolink:NamedThing	positive regulation of central tolerance induction	Any process that activates or increases the frequency, rate, or extent of central tolerance induction.	tmpzr1t_l9r_go_relaxed.owl	stimulation of central tolerance induction|activation of central tolerance induction|upregulation of central tolerance induction|up regulation of central tolerance induction|up-regulation of central tolerance induction													biological_process											owl:Class	
GO:0043233	biolink:NamedThing	organelle lumen	The internal volume enclosed by the membranes of a particular organelle; includes the volume enclosed by a single organelle membrane, e.g. endoplasmic reticulum lumen, or the volume enclosed by the innermost of the two lipid bilayers of an organelle envelope, e.g. nuclear lumen.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0042731	biolink:NamedThing	PH domain binding	Binding to a PH domain (pleckstrin homology) of a protein, a domain of about 100 residues that occurs in a wide range of proteins involved in intracellular signaling or as constituents of the cytoskeleton.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0090677	biolink:NamedThing	reversible differentiation	A phenotypic switching process where a cell reversibly differentiates and dedifferentiates from one cell type into another.	tmpzr1t_l9r_go_relaxed.owl								tb	2016-04-28T17:32:40Z					biological_process											owl:Class	
GO:0106118	biolink:NamedThing	regulation of sterol biosynthetic process	Any process that modulates the frequency, rate or extent of a sterol biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl								hjd	2018-04-19T17:41:06Z					biological_process											owl:Class	
GO:1990501	biolink:NamedThing	exon-exon junction subcomplex mago-y14	Component of the core exon-exon-junction complex (EJC). Fairly conserved in eukaryotes; in Drosophila, consists of the Mago and Y14 (tsunagi) gene products. Important for coupling nuclear and cytoplasmic events in gene expression. Inhibits the ATPase activity of eIF4AIII (Q9VHS8) to ensure a stable association of the EJC core with the mRNA.	tmpzr1t_l9r_go_relaxed.owl	MGN-RBM8A complex|exon junction subcomplex MAGOH-Y14|mago-y14 complex					An example of this is Mago in drome (P49028) in PMID:12730685 (inferred from direct assay).		bhm	2014-09-30T14:05:28Z					cellular_component											owl:Class	
GO:0035145	biolink:NamedThing	exon-exon junction complex	A multi-subunit complex deposited by the spliceosome upstream of messenger RNA exon-exon junctions. The exon-exon junction complex provides a binding platform for factors involved in mRNA export and nonsense-mediated mRNA decay.	tmpzr1t_l9r_go_relaxed.owl	EJC|exon junction complex													cellular_component											owl:Class	
GO:1903383	biolink:NamedThing	regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway	Any process that modulates the frequency, rate or extent of a hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	regulation of hydrogen peroxide-induced neuron apoptosis|regulation of H2O2-induced neuron intrinsic apoptotic signaling pathway|regulation of hydrogen peroxide-induced neuronal apoptosis|regulation of neuron intrinsic apoptotic signaling pathway in response to hydrogen peroxide|regulation of neuron apoptosis in response to hydrogen peroxide|regulation of neuron intrinsic apoptotic signaling pathway in response to H2O2|regulation of H2O2-induced neuron apoptosis							bf	2014-08-27T08:50:37Z					biological_process											owl:Class	
GO:2000142	biolink:NamedThing	regulation of DNA-templated transcription, initiation	Any process that modulates the frequency, rate or extent of DNA-templated transcription initiation.	tmpzr1t_l9r_go_relaxed.owl	regulation of transcription initiation, DNA-dependent|regulation of initiation of DNA-dependent transcription|regulation of DNA-dependent transcription, initiation							mah	2010-10-01T09:11:35Z					biological_process											owl:Class	
GO:0051785	biolink:NamedThing	positive regulation of nuclear division	Any process that activates or increases the frequency, rate or extent of nuclear division, the partitioning of the nucleus and its genetic information.	tmpzr1t_l9r_go_relaxed.owl	stimulation of nuclear division|activation of nuclear division|up regulation of nuclear division|upregulation of nuclear division|up-regulation of nuclear division													biological_process											owl:Class	
GO:0051783	biolink:NamedThing	regulation of nuclear division	Any process that modulates the frequency, rate or extent of nuclear division, the partitioning of the nucleus and its genetic information.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0061817	biolink:NamedThing	endoplasmic reticulum-plasma membrane tethering	The attachment of an endoplasmic reticulum membrane to the plasma membrane via molecular tethers.	tmpzr1t_l9r_go_relaxed.owl	ER-plasma membrane tethering							dph	2016-12-05T14:43:58Z					biological_process											owl:Class	
GO:0106297	biolink:NamedThing	E-series resolvin biosynthetic process	The chemical reactions and pathways resulting in the formation of resolvin family E-series, hydroxy fatty acids derived from icosapentaenoic acid.	tmpzr1t_l9r_go_relaxed.owl								hjd	2020-08-25T13:49:46Z					biological_process											owl:Class	
GO:1901373	biolink:NamedThing	lipid hydroperoxide transport	The directed movement of a lipid hydroperoxide into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl								tb	2012-09-28T00:24:39Z					biological_process											owl:Class	
GO:0002302	biolink:NamedThing	CD8-positive, alpha-beta T cell differentiation involved in immune response	The process in which an antigenically naive CD8-positive, alpha-beta T cell acquires the specialized features of an effector, regulatory, or memory T cell as part of an immune response. Effector T cells include cells which provide T cell help or exhibit cytotoxicity towards other cells.	tmpzr1t_l9r_go_relaxed.owl	CD8-positive, alpha-beta T cell differentiation during immune response|CD8-positive, alpha-beta intraepithelial T cell development|CD8-positive, alpha-beta T-lymphocyte differentiation during immune response|CD8-positive, alpha-beta T lymphocyte differentiation during immune response|CD8-positive, alpha-beta T-cell differentiation during immune response					Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.								biological_process											owl:Class	
GO:2000129	biolink:NamedThing	negative regulation of octopamine signaling pathway	Any process that stops, prevents, or reduces the frequency, rate or extent of octopamine signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of octopamine signalling pathway							mah	2010-09-29T09:29:44Z					biological_process											owl:Class	
GO:0004818	biolink:NamedThing	glutamate-tRNA ligase activity	Catalysis of the reaction: ATP + L-glutamate + tRNA(Glu) = AMP + diphosphate + L-glutamyl-tRNA(Glu).	tmpzr1t_l9r_go_relaxed.owl	glutamyl-transfer ribonucleic acid synthetase activity|glutamyl-transfer ribonucleate synthetase activity|glutamyl-transfer RNA synthetase activity|glutamic acid translase activity|glutamyl-tRNA synthetase activity|L-glutamate:tRNAGlu ligase (AMP-forming) activity|glutamate-tRNA synthetase activity				RHEA:23540|MetaCyc:GLURS-RXN|Reactome:R-HSA-379861|EC:6.1.1.17|Reactome:R-HSA-380216									molecular_function											owl:Class	
GO:1905665	biolink:NamedThing	positive regulation of calcium ion import across plasma membrane	Any process that activates or increases the frequency, rate or extent of calcium ion import across plasma membrane.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of calcium ion import across plasma membrane|upregulation of calcium ion import across plasma membrane|activation of calcium ion import across plasma membrane|up regulation of calcium ion import across plasma membrane					An example of this is PPP3CA in human (Q08209) in 17640527 (inferred from direct assay).		bhm	2016-11-11T09:26:23Z					biological_process											owl:Class	
GO:0047389	biolink:NamedThing	glycerophosphocholine phosphodiesterase activity	Catalysis of the reaction: H2O + L-1-glycero-3-phosphocholine = glycerol-3-phosphate + choline.	tmpzr1t_l9r_go_relaxed.owl	glycerophosphohydrolase activity|glycerophosphinicocholine diesterase activity|sn-glycero-3-phosphorylcholine diesterase activity|glycerolphosphorylcholine phosphodiesterase activity|glycerylphosphorylcholinediesterase activity|sn-glycero-3-phosphocholine glycerophosphohydrolase activity				MetaCyc:3.1.4.2-RXN|EC:3.1.4.2|RHEA:16061|Reactome:R-HSA-6814132									molecular_function											owl:Class	
GO:0052860	biolink:NamedThing	2'-deoxymugineic-acid 3-dioxygenase activity	Catalysis of the reaction: 2'-deoxymugineic acid + 2-oxoglutarate + O2 = 3-epihydroxy-2'-deoxymugineic acid + succinate + CO2.	tmpzr1t_l9r_go_relaxed.owl	2'-deoxymugineic acid,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating) activity				RHEA:20065|MetaCyc:RXN-7983|EC:1.14.11.25|KEGG_REACTION:R07187			ai	2011-12-05T06:00:58Z					molecular_function											owl:Class	
GO:0102341	biolink:NamedThing	3-oxo-lignoceroyl-CoA reductase activity	Catalysis of the reaction: (R)-3-hydroxylignoceroyl-CoA + NADP <=> 3-oxotetracosanoyl-CoA + NADPH + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-13300|EC:1.1.1.330									molecular_function											owl:Class	
GO:2000001	biolink:NamedThing	regulation of DNA damage checkpoint	Any process that modulates the frequency, rate or extent of a DNA damage checkpoint.	tmpzr1t_l9r_go_relaxed.owl	regulation of DNA damage response, signal transduction resulting in cell cycle arrest							jl	2010-07-15T03:25:00Z					biological_process											owl:Class	
GO:1901976	biolink:NamedThing	regulation of cell cycle checkpoint	Any process that modulates the frequency, rate or extent of cell cycle checkpoint.	tmpzr1t_l9r_go_relaxed.owl	regulation of G1/S checkpoint|regulation of G1/S transition checkpoint					Note that this term should not be used for direct manual annotation as it should always be possible to specify the type of checkpoint (i.e mitotic spindle or DNA damage etc).		jl	2013-03-06T15:10:20Z			GO:2001047		biological_process											owl:Class	
GO:0002186	biolink:NamedThing	cytosolic creatine kinase complex	A dimeric protein complex having creatine kinase activity.	tmpzr1t_l9r_go_relaxed.owl								hjd	2011-06-14T02:14:16Z					cellular_component											owl:Class	
GO:0002185	biolink:NamedThing	creatine kinase complex	A protein complex having creatine kinase activity.	tmpzr1t_l9r_go_relaxed.owl								hjd	2011-06-14T02:12:19Z					cellular_component											owl:Class	
GO:0071089	biolink:NamedThing	alphaV-beta3 integrin-tissue transglutaminase complex	A protein complex that consists of an alphaV-beta3 integrin complex bound to tissue transglutaminase.	tmpzr1t_l9r_go_relaxed.owl	ITGAV-ITGB3-TGM2 complex							mah	2009-11-06T04:46:02Z					cellular_component											owl:Class	
GO:0002787	biolink:NamedThing	negative regulation of antibacterial peptide production	Any process that stops, prevents, or reduces the frequency, rate, or extent of antibacterial peptide production.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of antibacterial peptide production|down regulation of antibacterial peptide production|inhibition of antibacterial peptide production|downregulation of antibacterial peptide production													biological_process											owl:Class	
GO:0046881	biolink:NamedThing	positive regulation of follicle-stimulating hormone secretion	Any process that activates or increases the frequency, rate or extent of the regulated release of follicle-stimulating hormone.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of follicle stimulating hormone secretion|stimulation of follicle-stimulating hormone secretion|up regulation of follicle-stimulating hormone secretion|activation of follicle-stimulating hormone secretion|upregulation of follicle-stimulating hormone secretion|up-regulation of follicle-stimulating hormone secretion													biological_process											owl:Class	
GO:0032278	biolink:NamedThing	positive regulation of gonadotropin secretion	Any process that activates or increases the frequency, rate or extent of the regulated release of a gonadotropin.	tmpzr1t_l9r_go_relaxed.owl	activation of gonadotropin secretion|up-regulation of gonadotropin secretion|up regulation of gonadotropin secretion|stimulation of gonadotropin secretion|positive regulation of gonadotrophin secretion|upregulation of gonadotropin secretion													biological_process											owl:Class	
GO:1903091	biolink:NamedThing	pyridoxamine transmembrane transport	The process in which pyridoxamine is transported across a membrane.	tmpzr1t_l9r_go_relaxed.owl								al	2014-06-03T10:41:20Z					biological_process											owl:Class	
GO:0034413	biolink:NamedThing	ascospore wall (1->3)-beta-D-glucan biosynthetic process	The chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds, found in the walls of ascospores.	tmpzr1t_l9r_go_relaxed.owl	ascospore wall beta-1,3-glucan synthesis|ascospore wall beta-1,3-glucan biosynthesis|ascospore wall 1,3-beta-glucan anabolism|ascospore wall beta-1,3-glucan anabolism|ascospore wall 1,3-beta-glucan synthesis|ascospore wall 1,3-beta-glucan biosynthesis|ascospore wall 1,3-beta-glucan biosynthetic process|ascospore wall beta-1,3-glucan biosynthetic process|ascospore wall 1,3-beta-glucan formation|ascospore wall beta-1,3-glucan formation|ascospore wall 1,3-beta-D-glucan biosynthetic process													biological_process											owl:Class	
GO:0006238	biolink:NamedThing	CMP salvage	Any process that generates CMP, cytidine monophosphate, from derivatives of it without de novo synthesis.	tmpzr1t_l9r_go_relaxed.owl	cytidine monophosphate salvage													biological_process											owl:Class	
GO:0055106	biolink:NamedThing	ubiquitin-protein transferase regulator activity	Binds to and modulates the activity of a ubiquitin-protein transferase, an enzyme that catalyzes the covalent attachment of ubiquitin to lysine in a substrate protein.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0032506	biolink:NamedThing	cytokinetic process	A cellular process that is involved in cytokinesis (the division of the cytoplasm of a cell and its separation into two daughter cells).	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0008781	biolink:NamedThing	N-acylneuraminate cytidylyltransferase activity	Catalysis of the reaction: CTP + N-acylneuraminate = diphosphate + CMP-N-acylneuraminate.	tmpzr1t_l9r_go_relaxed.owl	cytidine monophosphosialate pyrophosphorylase activity|CMP-sialate synthetase activity|cytidine monophosphoacetylneuraminic synthetase activity|cytidine 5-monophosphate N-acetylneuraminic acid synthetase activity|CMP-sialic acid synthetase activity|cytidine monophosphosialate synthetase activity|CMP-NeuAc synthetase activity|CMP-NeuNAc synthetase activity|cytidine 5'-monophospho-N-acetylneuraminic acid synthetase activity|cytidine 5'-monophosphosialic acid synthetase activity|CMP-sialate diphosphorylase activity|acylneuraminate cytidyltransferase activity|cytidine monophosphosialic acid synthetase activity|CMP-Neu5Ac synthetase activity|CMP-sialate pyrophosphorylase activity|CMP-sialic synthetase activity|CMP-N-acetylneuraminate synthetase activity|CMP-sialate synthase activity|CMP-N-acetylneuraminate synthase activity|CMP-NANA synthetase activity|CTP:N-acylneuraminate cytidylyltransferase activity|acetylneuraminate cytidylyltransferase activity|CMP-N-acetylneuraminic acid synthase activity|CMP-N-acetylneuraminic acid synthetase activity				RHEA:11344|Reactome:R-HSA-4084982|MetaCyc:ACYLNEURAMINATE-CYTIDYLYLTRANSFERASE-RXN|EC:2.7.7.43									molecular_function											owl:Class	
GO:0046287	biolink:NamedThing	isoflavonoid metabolic process	The chemical reactions and pathways involving isoflavonoids, a group of water-soluble phenolic derivatives, isomeric with flavonoids, containing a flavan skeleton. They are differentiated from flavonoids by the point of attachment of the aromatic ring group.	tmpzr1t_l9r_go_relaxed.owl	isoflavonoid metabolism													biological_process											owl:Class	
GO:0048260	biolink:NamedThing	positive regulation of receptor-mediated endocytosis	Any process that activates or increases the frequency, rate or extent of receptor mediated endocytosis, the uptake of external materials by cells, utilizing receptors to ensure specificity of transport.	tmpzr1t_l9r_go_relaxed.owl	activation of receptor mediated endocytosis|positive regulation of receptor mediated endocytosis|up-regulation of receptor mediated endocytosis|stimulation of receptor mediated endocytosis|upregulation of receptor mediated endocytosis|up regulation of receptor mediated endocytosis													biological_process											owl:Class	
GO:0008924	biolink:NamedThing	malate dehydrogenase (quinone) activity	Catalysis of the reaction: (S)-malate + a quinone = oxaloacetate + a quinol.	tmpzr1t_l9r_go_relaxed.owl	FAD-dependent malate dehydrogenase activity|(S)-malate:quinone oxidoreductase activity|(S)-malate:(quinone) oxidoreductase activity|MQO activity				RHEA:46012|EC:1.1.5.4|MetaCyc:MALATE-DEHYDROGENASE-ACCEPTOR-RXN									molecular_function											owl:Class	
GO:0016901	biolink:NamedThing	oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces a quinone or a similar acceptor molecule.	tmpzr1t_l9r_go_relaxed.owl					EC:1.1.5.-									molecular_function											owl:Class	
GO:0000149	biolink:NamedThing	SNARE binding	Binding to a SNARE (soluble N-ethylmaleimide-sensitive factor attached protein receptor) protein.	tmpzr1t_l9r_go_relaxed.owl	SNAP receptor binding				Reactome:R-HSA-265166|Reactome:R-HSA-376364|Reactome:R-HSA-374922|Reactome:R-HSA-380905|Reactome:R-HSA-210426|Reactome:R-HSA-380869|Reactome:R-HSA-9023173|Reactome:R-HSA-374899|Reactome:R-HSA-888589|Reactome:R-HSA-210430|Reactome:R-HSA-376357|Reactome:R-HSA-372529|Reactome:R-HSA-380574|Reactome:R-HSA-917744|Reactome:R-HSA-376369|Reactome:R-HSA-380901|Reactome:R-HSA-372505									molecular_function											owl:Class	
GO:0031108	biolink:NamedThing	holo-[acyl-carrier-protein] biosynthetic process	The chemical reactions and pathways resulting in the formation of holo-[acyl-carrier protein].	tmpzr1t_l9r_go_relaxed.owl	holo-[acyl-carrier-protein] formation|holo-[acyl-carrier-protein] biosynthesis|holo-[acyl-carrier-protein] anabolism|holo-[acyl-carrier protein] biosynthesis|holo-[acyl-carrier-protein] synthesis													biological_process											owl:Class	
GO:2000924	biolink:NamedThing	regulation of cellodextrin metabolic process	Any process that modulates the frequency, rate or extent of cellodextrin metabolic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of cellodextrin metabolism							tt	2011-08-01T12:39:52Z					biological_process											owl:Class	
GO:0002695	biolink:NamedThing	negative regulation of leukocyte activation	Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte activation.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of leucocyte activation|down-regulation of leukocyte activation|inhibition of leukocyte activation|negative regulation of immune cell activation|downregulation of leukocyte activation|down regulation of leukocyte activation													biological_process											owl:Class	
GO:0015137	biolink:NamedThing	citrate transmembrane transporter activity	Enables the transfer of citrate, 2-hydroxy-1,2,3-propanetricarboyxlate, from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	tricarboxylate transport protein				Reactome:R-HSA-433104|TC:2.A.29.7.2									molecular_function											owl:Class	
GO:0015142	biolink:NamedThing	tricarboxylic acid transmembrane transporter activity	Enables the transfer of tricarboxylic acids from one side of a membrane to the other. Tricarboxylic acid are organic acids with three COOH groups.	tmpzr1t_l9r_go_relaxed.owl	sodium:dicarboxylate/tricarboxylate symporter activity				Reactome:R-HSA-75849|Reactome:R-HSA-372449									molecular_function											owl:Class	
GO:0018830	biolink:NamedThing	gamma-hexachlorocyclohexane dehydrochlorinase activity	Catalysis of the reaction: gamma-hexachlorocyclohexane + HCl = 1,3(R),4(S),5(S),6(R)-pentachlorocyclohexene.	tmpzr1t_l9r_go_relaxed.owl					EC:4.5.1.-|UM-BBD_enzymeID:e0359									molecular_function											owl:Class	
GO:0034833	biolink:NamedThing	geranylate CoA-transferase activity	Catalysis of the reaction: geranylate + CoASH = trans-geranyl-CoA + OH-.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r1165									molecular_function											owl:Class	
GO:0035008	biolink:NamedThing	positive regulation of melanization defense response	Any process that increases the rate or extent of the melanization defense response during injury or invasion.	tmpzr1t_l9r_go_relaxed.owl	stimulation of melanization defense response|activation of melanization defense response|positive regulation of melanization defence response|upregulation of melanization defense response|up regulation of melanization defense response|up-regulation of melanization defense response													biological_process											owl:Class	
GO:0097051	biolink:NamedThing	establishment of protein localization to endoplasmic reticulum membrane	The directed movement of a protein to a specific location in the endoplasmic reticulum membrane.	tmpzr1t_l9r_go_relaxed.owl	establishment of protein localisation in endoplasmic reticulum membrane|establishment of protein localization in endoplasmic reticulum membrane							pr	2011-05-04T05:55:26Z					biological_process											owl:Class	
GO:0051081	biolink:NamedThing	nuclear membrane disassembly	The controlled breakdown of the nuclear membranes, for example during  cellular division.	tmpzr1t_l9r_go_relaxed.owl	nuclear envelope breakdown|nuclear envelope degradation|nuclear envelope disassembly|nuclear envelope catabolism													biological_process											owl:Class	
GO:0102480	biolink:NamedThing	5-fluorocytosine deaminase activity	Catalysis of the reaction: H+ + flucytosine + H2O <=> 5-fluorouracil + ammonium.	tmpzr1t_l9r_go_relaxed.owl					EC:3.5.4.1|MetaCyc:RXN-14129									molecular_function											owl:Class	
GO:0051738	biolink:NamedThing	xanthophyll binding	Binding to xanthophylls, any of several neutral yellow to orange carotenoid pigments containing oxygen.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0061220	biolink:NamedThing	mesonephric macula densa development	The process whose specific outcome is the progression of the mesonephric macula densa over time, from its formation to the mature structure. The mesonephric macula densa is an area of specialized cells in the distal tubule of the mesonephros that makes contact with the vascular pole of the glomerulus.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-08-19T01:11:41Z					biological_process											owl:Class	
GO:0032292	biolink:NamedThing	peripheral nervous system axon ensheathment	The process in which a Schwann cell membrane closes around an axon in the peripheral nervous system. This can be a myelinating or a non-myelinating neuron-glial interaction.	tmpzr1t_l9r_go_relaxed.owl	ensheathment of axons in peripheral nervous system													biological_process											owl:Class	
GO:0004860	biolink:NamedThing	protein kinase inhibitor activity	Binds to and stops, prevents or reduces the activity of a protein kinase, an enzyme which phosphorylates a protein.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0019210	biolink:NamedThing	kinase inhibitor activity	Binds to and stops, prevents or reduces the activity of a kinase.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0016151	biolink:NamedThing	nickel cation binding	Binding to a nickel (Ni) cation.	tmpzr1t_l9r_go_relaxed.owl	nickel binding|Ni binding													molecular_function											owl:Class	
GO:0022608	biolink:NamedThing	multicellular organism adhesion	The attachment of a multicellular organism to a substrate or other organism.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0060367	biolink:NamedThing	sagittal suture morphogenesis	The process in which the sagittal suture is generated and organized.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0060363	biolink:NamedThing	cranial suture morphogenesis	The process in which any suture between cranial bones is generated and organized.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0032537	biolink:NamedThing	host-seeking behavior	The specific behavior of an organism that are associated with finding a host organism; may include behavioral responses to light, temperature, or chemical emanations from the prospective host.	tmpzr1t_l9r_go_relaxed.owl	host-seeking behaviour													biological_process											owl:Class	
GO:0070853	biolink:NamedThing	myosin VI binding	Binding to a class VI myosin. The myosin VI heavy chain has a single IQ motif in the neck and a tail region with a coiled coil domain followed by a unique globular domain, a unique insertion that enables myosin VI to move towards the pointed or minus end of actin filaments.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-08-13T01:28:36Z					molecular_function											owl:Class	
GO:0010933	biolink:NamedThing	positive regulation of macrophage tolerance induction	Any process that increases the frequency, rate, or extent of B cell tolerance induction.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0045098	biolink:NamedThing	type III intermediate filament	A type of intermediate filament, typically made up of one or more of the proteins vimentin, desmin, glial fibrillary acidic protein (GFAP), and peripherin. Unlike the keratins, the type III proteins can form both homo- and heteropolymeric IF filaments.	tmpzr1t_l9r_go_relaxed.owl	vimentin|desmin|glial fibrillary acidic protein|peripherin|type III intermediate filament associated protein													cellular_component											owl:Class	
GO:0035433	biolink:NamedThing	acetate transmembrane transport	The process in which acetate is transported across a membrane. Acetate is the 2-carbon carboxylic acid ethanoic acid.	tmpzr1t_l9r_go_relaxed.owl	acetate membrane transport					Note that this term is not intended for use in annotating lateral movement within membranes.		bf	2010-04-08T10:59:01Z					biological_process											owl:Class	
GO:0006846	biolink:NamedThing	acetate transport	The directed movement of acetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:2000548	biolink:NamedThing	negative regulation of dendritic cell dendrite assembly	Any process that stops, prevents or reduces the frequency, rate or extent of dendritic cell dendrite assembly.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of dendritic extension							ebc	2011-04-03T07:22:01Z					biological_process											owl:Class	
GO:0052700	biolink:NamedThing	ergothioneine catabolic process	The chemical reactions and pathways resulting in the breakdown of ergothioneine, a naturally occurring metabolite of histidine with antioxidant properties.	tmpzr1t_l9r_go_relaxed.owl	(2S)-3-(2-mercapto-1H-imidazol-5-yl)-2-(trimethylazaniumyl)propanoate catabolic process|2-mercaptoergothioneine trimethylbetaine breakdown|2-mercaptoergothioneine trimethylbetaine degradation|2-mercaptoergothioneine trimethylbetaine catabolic process|ergothioneine breakdown|ergothioneine degradation|ergothioneine catabolism|2-mercaptoergothioneine trimethylbetaine catabolism							ai	2011-08-01T03:56:22Z					biological_process											owl:Class	
GO:0015631	biolink:NamedThing	tubulin binding	Binding to monomeric or multimeric forms of tubulin, including microtubules.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0048544	biolink:NamedThing	recognition of pollen	The process, involving the sharing and interaction of the single locus incompatibility haplotypes, involved in the recognition or rejection of the self pollen by cells in the stigma. This process ensures out-breeding in certain plant species.	tmpzr1t_l9r_go_relaxed.owl	self incompatibility|pollen recognition|recognition or rejection of self pollen											GO:0009857		biological_process											owl:Class	
GO:0005463	biolink:NamedThing	UDP-N-acetylgalactosamine transmembrane transporter activity	Enables the transfer of a N-acetylgalactosamine from one side of a membrane to the other. N-acetylgalactosamine is a substance composed of N-acetylgalactosamine, a common structural unit of oligosaccharides, in glycosidic linkage with uridine diphosphate.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1905871	biolink:NamedThing	regulation of protein localization to cell leading edge	Any process that modulates the frequency, rate or extent of protein localization to cell leading edge.	tmpzr1t_l9r_go_relaxed.owl	regulation of protein localization in cell leading edge|regulation of protein localisation to cell leading edge|regulation of protein localisation in cell leading edge							sl	2017-01-27T19:34:55Z					biological_process											owl:Class	
GO:0047790	biolink:NamedThing	creatinine deaminase activity	Catalysis of the reaction: creatinine + H2O = N-methylhydantoin + NH3.	tmpzr1t_l9r_go_relaxed.owl	creatinine desiminase activity|creatinine hydrolase|creatinine iminohydrolase activity				EC:3.5.4.21|MetaCyc:CREATININE-DEAMINASE-RXN|RHEA:12681									molecular_function											owl:Class	
GO:0007172	biolink:NamedThing	signal complex assembly	The aggregation, arrangement and bonding together of a set of components to form a complex capable of relaying a signal within a cell.	tmpzr1t_l9r_go_relaxed.owl	signal complex formation													biological_process											owl:Class	
GO:0033335	biolink:NamedThing	anal fin development	The process whose specific outcome is the progression of the anal fin over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0097698	biolink:NamedThing	telomere maintenance via base-excision repair	A telomere maintenance process that occurs by base-excision repair of telomeric DNA in response to DNA damage. Telomeric sequences are particularly susceptible to oxidative DNA damage, due to their G-rich nature.	tmpzr1t_l9r_go_relaxed.owl								pr	2016-01-07T11:15:39Z					biological_process											owl:Class	
GO:0005114	biolink:NamedThing	type II transforming growth factor beta receptor binding	Binding to a type II transforming growth factor beta receptor.	tmpzr1t_l9r_go_relaxed.owl	punt binding|type II TGF-beta binding|TGF-beta type II binding|transforming growth factor beta receptor type II binding|punt ligand|transforming growth factor beta ligand binding to type II receptor													molecular_function											owl:Class	
GO:0005160	biolink:NamedThing	transforming growth factor beta receptor binding	Binding to a transforming growth factor beta receptor.	tmpzr1t_l9r_go_relaxed.owl	activin|transforming growth factor beta receptor anchoring activity|TGF-beta receptor binding|TGFbeta receptor binding|inhibin|transforming growth factor beta ligand binding to type I receptor|transforming growth factor beta|transforming growth factor beta ligand binding to type II receptor|transforming growth factor beta receptor ligand													molecular_function											owl:Class	
GO:1901028	biolink:NamedThing	regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway	Any process that modulates the frequency, rate or extent of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	regulation of MOMP|regulation of mitochondrial outer membrane permeabilization							pr	2012-06-20T09:19:16Z					biological_process											owl:Class	
GO:0018919	biolink:NamedThing	gamma-1,2,3,4,5,6-hexachlorocyclohexane metabolic process	The chemical reactions and pathways involving gamma-1,2,3,4,5,6-hexachlorocyclohexane (also known as Lindane), the most common form of hexachlorohexane, a halogenated organic insecticide that has been used worldwide for agriculture and public health.	tmpzr1t_l9r_go_relaxed.owl	gamma-1,2,3,4,5,6-hexachlorocyclohexane metabolism				MetaCyc:GAMMAHEXCHLORDEG-PWY|UM-BBD_pathwayID:ghch									biological_process											owl:Class	
GO:0019497	biolink:NamedThing	hexachlorocyclohexane metabolic process	The chemical reactions and pathways involving hexachlorocyclohexane, a cyclohexane derivative with 6 chlorine atoms attached to the hexane ring. Hexachlorocyclohexane consists of a mixture of 8 different isomers and was used a commercial insecticide. It is persistent in the environment, causing serious soil pollution.	tmpzr1t_l9r_go_relaxed.owl	hexachlorocyclohexane metabolism													biological_process											owl:Class	
GO:0007302	biolink:NamedThing	nurse cell nucleus anchoring	Attachment of the nurse cell nucleus to the plasma membrane.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1904219	biolink:NamedThing	positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity	Any process that activates or increases the frequency, rate or extent of CDP-diacylglycerol-serine O-phosphatidyltransferase activity.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of CDPdiglyceride-serine O-phosphatidyltransferase activity|up regulation of cytidine 5'-diphospho-1,2-diacyl-sn-glycerol (CDPdiglyceride):L-serine O-phosphatidyltransferase activity|up regulation of phosphatidylserine synthetase activity|upregulation of phosphatidylserine synthase activity|upregulation of CDP-diglyceride:serine phosphatidyltransferase activity|up regulation of CDP-diglyceride-L-serine phosphatidyltransferase activity|upregulation of CDPdiacylglycerol-serine O-phosphatidyltransferase activity|up regulation of CDP-diacylglycerol:L-serine 3-O-phosphatidyltransferase activity|positive regulation of PS synthase activity|positive regulation of CDPdiglyceride-serine O-phosphatidyltransferase activity|up-regulation of cytidine 5'-diphospho-1,2-diacyl-sn-glycerol (CDPdiglyceride):L-serine O-phosphatidyltransferase activity|activation of PS synthase activity|activation of phosphatidylserine synthetase activity|activation of CDP-diglyceride-L-serine phosphatidyltransferase activity|up-regulation of CDP-diglyceride:serine phosphatidyltransferase activity|upregulation of CDP-diacylglycerol:L-serine 3-O-phosphatidyltransferase activity|activation of cytidine 5'-diphospho-1,2-diacyl-sn-glycerol:L-serine O-phosphatidyltransferase activity|up regulation of CDPdiglyceride-serine O-phosphatidyltransferase activity|positive regulation of CDP-diacylglycerol:L-serine 3-O-phosphatidyltransferase activity|up-regulation of CDP-diglycerine-serine O-phosphatidyltransferase activity|activation of CDP-diacylglycerol:L-serine 3-O-phosphatidyltransferase activity|activation of CDP-diacylglycerol-L-serine O-phosphatidyltransferase activity|upregulation of CDPdiglyceride-serine O-phosphatidyltransferase activity|positive regulation of cytidine 5'-diphospho-1,2-diacyl-sn-glycerol:L-serine O-phosphatidyltransferase activity|positive regulation of phosphatidylserine synthase activity|positive regulation of CDP-diglyceride:serine phosphatidyltransferase activity|positive regulation of CDPdiacylglycerol-serine O-phosphatidyltransferase activity|positive regulation of CDP-diglyceride-L-serine phosphatidyltransferase activity|upregulation of cytidine 5'-diphospho-1,2-diacyl-sn-glycerol:L-serine O-phosphatidyltransferase activity|up regulation of phosphatidylserine synthase activity|activation of phosphatidylserine synthase activity|up-regulation of CDP-diacylglycerol:L-serine 3-O-phosphatidyltransferase activity|up-regulation of CDP-diacylglycerol-L-serine O-phosphatidyltransferase activity|activation of CDPdiglyceride-serine O-phosphatidyltransferase activity|positive regulation of CDP-diacylglycerol-L-serine O-phosphatidyltransferase activity|up-regulation of cytidine diphosphoglyceride-serine O-phosphatidyltransferase activity|up-regulation of CDP-diglyceride-L-serine phosphatidyltransferase activity|up-regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity|activation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity|activation of cytidine diphosphoglyceride-serine O-phosphatidyltransferase activity|upregulation of cytidine diphosphoglyceride-serine O-phosphatidyltransferase activity|positive regulation of CDP-diglycerine-serine O-phosphatidyltransferase activity|upregulation of PS synthase activity|up-regulation of CDPdiacylglycerol-serine O-phosphatidyltransferase activity|up regulation of CDP-diacylglycerol-L-serine O-phosphatidyltransferase activity|upregulation of phosphatidylserine synthetase activity|positive regulation of phosphatidylserine synthetase activity|activation of cytidine 5'-diphospho-1,2-diacyl-sn-glycerol (CDPdiglyceride):L-serine O-phosphatidyltransferase activity|up regulation of CDP-diglyceride:serine phosphatidyltransferase activity|up regulation of CDPdiacylglycerol-serine O-phosphatidyltransferase activity|activation of CDP-diglycerine-serine O-phosphatidyltransferase activity|up regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity|activation of CDP-diglyceride:serine phosphatidyltransferase activity|up-regulation of phosphatidylserine synthetase activity|up regulation of cytidine 5'-diphospho-1,2-diacyl-sn-glycerol:L-serine O-phosphatidyltransferase activity|up-regulation of cytidine 5'-diphospho-1,2-diacyl-sn-glycerol:L-serine O-phosphatidyltransferase activity|positive regulation of cytidine diphosphoglyceride-serine O-phosphatidyltransferase activity|upregulation of CDP-diacylglycerol-L-serine O-phosphatidyltransferase activity|upregulation of cytidine 5'-diphospho-1,2-diacyl-sn-glycerol (CDPdiglyceride):L-serine O-phosphatidyltransferase activity|up-regulation of phosphatidylserine synthase activity|upregulation of CDP-diglycerine-serine O-phosphatidyltransferase activity|upregulation of CDP-diglyceride-L-serine phosphatidyltransferase activity|activation of CDPdiacylglycerol-serine O-phosphatidyltransferase activity|upregulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity|up regulation of PS synthase activity|positive regulation of cytidine 5'-diphospho-1,2-diacyl-sn-glycerol (CDPdiglyceride):L-serine O-phosphatidyltransferase activity|up regulation of cytidine diphosphoglyceride-serine O-phosphatidyltransferase activity|up regulation of CDP-diglycerine-serine O-phosphatidyltransferase activity|up-regulation of PS synthase activity					Serinc proteins form a complex with serine and sphingolipid biosynthesis enzymes and regulates their activity through regulation of availability of the substrate		rl	2015-05-15T08:18:35Z					biological_process											owl:Class	
GO:0032917	biolink:NamedThing	polyamine acetylation	The modification of polyamines by addition of acetyl groups.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0022851	biolink:NamedThing	GABA-gated chloride ion channel activity	Enables the transmembrane transfer of a chloride ion by a channel that opens when GABA has been bound by the channel complex or one of its constituent parts.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0099095	biolink:NamedThing	ligand-gated anion channel activity	Enables the transmembrane transfer of an inorganic anion by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1903878	biolink:NamedThing	11-deoxycorticosterone binding	Binding to 11-deoxycorticosterone.	tmpzr1t_l9r_go_relaxed.owl								mr	2015-02-06T16:03:03Z					molecular_function											owl:Class	
GO:1990239	biolink:NamedThing	steroid hormone binding	Binding to a steroid hormone.	tmpzr1t_l9r_go_relaxed.owl								pr	2013-11-15T09:26:18Z					molecular_function											owl:Class	
GO:0034322	biolink:NamedThing	alcohol O-decanoyltransferase activity	Catalysis of the reaction: decanoyl-CoA + an alcohol = CoA + a decyl ester.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0034325	biolink:NamedThing	O-decanoyltransferase activity	Catalysis of the transfer of a decyl group to an oxygen atom on the acceptor molecule.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0090239	biolink:NamedThing	regulation of histone H4 acetylation	Any process that modulates the rate, frequency, or extent of histone H4 acetylation, the modification of histone H4 by the addition of an acetyl group.	tmpzr1t_l9r_go_relaxed.owl								tb	2010-01-20T03:48:09Z					biological_process											owl:Class	
GO:0003147	biolink:NamedThing	neural crest cell migration involved in heart formation	The characteristic movement of a cell from the dorsal ridge of the neural tube towards the heart and that contributes to heart formation.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-09-22T04:29:55Z					biological_process											owl:Class	
GO:0036021	biolink:NamedThing	endolysosome lumen	The volume enclosed by the membrane of an endolysosome. An endolysosome is a transient hybrid organelle formed by fusion of a late endosome with a lysosome.	tmpzr1t_l9r_go_relaxed.owl	endolysosomal lumen							bf	2011-10-13T04:32:31Z					cellular_component											owl:Class	
GO:0035205	biolink:NamedThing	positive regulation of lamellocyte differentiation	Any process that activates or increases the frequency, rate or extent of lamellocyte differentiation. Lamellocytes differentiate massively in the lymph glands after parasitization and are large flat cells devoted to encapsulation of invaders too large to be phagocytosed by plasmatocytes.	tmpzr1t_l9r_go_relaxed.owl	upregulation of lamellocyte differentiation|stimulation of lamellocyte differentiation|activation of lamellocyte differentiation|up-regulation of lamellocyte differentiation|up regulation of lamellocyte differentiation													biological_process											owl:Class	
GO:0035203	biolink:NamedThing	regulation of lamellocyte differentiation	Any process that modulates the frequency, rate or extent of lamellocyte differentiation. Lamellocytes differentiate massively in the lymph glands after parasitization and are large flat cells devoted to encapsulation of invaders too large to be phagocytosed by plasmatocytes.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1904100	biolink:NamedThing	positive regulation of protein O-linked glycosylation	Any process that activates or increases the frequency, rate or extent of protein O-linked glycosylation.	tmpzr1t_l9r_go_relaxed.owl	up regulation of protein amino acid O-linked glycosylation|activation of protein O-linked glycosylation|up-regulation of protein O-linked glycosylation|positive regulation of protein amino acid O-linked glycosylation|up-regulation of protein amino acid O-linked glycosylation|up regulation of protein O-linked glycosylation|upregulation of protein O-linked glycosylation|activation of protein amino acid O-linked glycosylation|upregulation of protein amino acid O-linked glycosylation							krc	2015-03-27T16:10:10Z					biological_process											owl:Class	
GO:0023026	biolink:NamedThing	MHC class II protein complex binding	Binding to a class II major histocompatibility complex.	tmpzr1t_l9r_go_relaxed.owl									2010-02-16T09:30:50Z					molecular_function											owl:Class	
GO:0023023	biolink:NamedThing	MHC protein complex binding	Binding to a major histocompatibility complex.	tmpzr1t_l9r_go_relaxed.owl									2010-02-16T09:30:50Z					molecular_function											owl:Class	
GO:0010223	biolink:NamedThing	secondary shoot formation	The process that gives rise to secondary (or auxiliary or axillary) shoots in plants. This process pertains to the initial formation of a structure from unspecified parts. These secondary shoots originate from secondary meristems initiated in the axils of leaf primordia. Axillary meristems function like the shoot apical meristem of the primary shoot initating the development of lateral organs.	tmpzr1t_l9r_go_relaxed.owl	shoot branching|axillary shoot formation|axillary shoot system formation|auxiliary shoot formation													biological_process											owl:Class	
GO:0070454	biolink:NamedThing	negative regulation of heme biosynthetic process	Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of heme.	tmpzr1t_l9r_go_relaxed.owl	downregulation of heme biosynthetic process|negative regulation of heme anabolism|down regulation of heme biosynthetic process|negative regulation of heme synthesis|negative regulation of heme formation|negative regulation of haem biosynthetic process|inhibition of heme biosynthetic process|negative regulation of heme biosynthesis|down-regulation of heme biosynthetic process													biological_process											owl:Class	
GO:0070453	biolink:NamedThing	regulation of heme biosynthetic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of heme.	tmpzr1t_l9r_go_relaxed.owl	regulation of haem biosynthetic process|regulation of haem biosynthesis|regulation of heme biosynthesis|regulation of heme formation|regulation of heme synthesis|regulation of heme anabolism													biological_process											owl:Class	
GO:0019978	biolink:NamedThing	interleukin-3 binding	Binding to interleukin-3.	tmpzr1t_l9r_go_relaxed.owl	IL-3 binding													molecular_function											owl:Class	
GO:0051877	biolink:NamedThing	pigment granule aggregation in cell center	The directed movement of dispersed pigment granules towards the center of the cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0051905	biolink:NamedThing	establishment of pigment granule localization	The directed movement of a pigment granule to a specific location.	tmpzr1t_l9r_go_relaxed.owl	establishment of pigment granule localisation													biological_process											owl:Class	
GO:0043174	biolink:NamedThing	nucleoside salvage	Any process which produces a nucleotide, a nucleobase linked to either beta-D-ribofuranose (ribonucleoside) or 2-deoxy-beta-D-ribofuranose (a deoxyribonucleotide), from derivatives of it without de novo synthesis.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1900865	biolink:NamedThing	chloroplast RNA modification	Any RNA modification that takes place in chloroplast.	tmpzr1t_l9r_go_relaxed.owl	RNA editing in chloroplast							tb	2012-06-11T10:58:04Z					biological_process											owl:Class	
GO:0002565	biolink:NamedThing	somatic diversification of immune receptors via gene conversion	The process in which immune receptor genes are diversified through gene conversion.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0016444	biolink:NamedThing	somatic cell DNA recombination	Recombination occurring within or between DNA molecules in somatic cells.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:2001231	biolink:NamedThing	regulation of protein localization to prospore membrane	Any process that modulates the frequency, rate or extent of protein localization to prospore membrane.	tmpzr1t_l9r_go_relaxed.owl	regulation of protein-prospore membrane targeting|regulation of protein targeting to ascospore-type prospore membrane|regulation of protein localisation to prospore membrane|regulation of protein targeting to forespore membrane|regulation of protein targeting to FSM|regulation of protein targeting to prospore membrane							mah	2011-11-21T04:13:30Z					biological_process											owl:Class	
GO:0034996	biolink:NamedThing	RasGAP-Fyn-Lyn-Yes complex	A protein complex that consists of a GTPase activator protein (GAP) for Ras and three Src family protein tyrosine kinases, Fyn, Lyn and Yes. The complex is involved in signaling upon platelet activation.	tmpzr1t_l9r_go_relaxed.owl	p21(ras)GAP-Fyn-Lyn-Yes complex, thrombin stimulated					Note that the gene/protein name 'APC' should not be confused with the abbreviation for 'anaphase promoting complex'.								cellular_component											owl:Class	
GO:0021529	biolink:NamedThing	spinal cord oligodendrocyte cell differentiation	The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of oligodendrocytes. Oligodendrocytes are non-neuronal cells. The primary function of oligodendrocytes is the myelination of nerve axons in the central nervous system. Differentiation includes the processes involved in commitment of a cell to a specific fate.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0032701	biolink:NamedThing	negative regulation of interleukin-18 production	Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-18 production.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of interleukin-18 production|inhibition of interleukin-18 production|downregulation of interleukin-18 production|down regulation of interleukin-18 production|negative regulation of interleukin-18 biosynthetic process|negative regulation of interleukin-18 secretion|negative regulation of IL-18 production											GO:0045382|GO:0150121		biological_process											owl:Class	
GO:0032661	biolink:NamedThing	regulation of interleukin-18 production	Any process that modulates the frequency, rate, or extent of interleukin-18 production.	tmpzr1t_l9r_go_relaxed.owl	regulation of interleukin-18 biosynthetic process|regulation of IL-18 production|regulation of interleukin-18 secretion											GO:0045381|GO:0150120		biological_process											owl:Class	
GO:0140486	biolink:NamedThing	zinc ion sequestering activity	The selective interaction of a protein with a zinc ion to prevent it from interacting with sensitive components of a biological system.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/19700						pg	2020-06-29T09:21:42Z					molecular_function											owl:Class	
GO:1903042	biolink:NamedThing	negative regulation of chondrocyte hypertrophy	Any process that stops, prevents or reduces the frequency, rate or extent of chondrocyte hypertrophy.	tmpzr1t_l9r_go_relaxed.owl	downregulation of chondrocyte hypertrophy|down-regulation of chondrocyte hypertrophy|inhibition of chondrocyte hypertrophy|down regulation of chondrocyte hypertrophy							mr	2014-05-20T21:23:19Z					biological_process											owl:Class	
GO:0061182	biolink:NamedThing	negative regulation of chondrocyte development	Any process that decreases the rate, frequency, or extent of the process whose specific outcome is the progression of a chondrocyte over time, from its commitment to its mature state. Chondrocyte development does not include the steps involved in committing a chondroblast to a chondrocyte fate.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-07-14T08:33:05Z					biological_process											owl:Class	
GO:0050427	biolink:NamedThing	3'-phosphoadenosine 5'-phosphosulfate metabolic process	The chemical reactions and pathways involving 3'-phosphoadenosine 5'-phosphosulfate, a naturally occurring mixed anhydride. It is an intermediate in the formation of a variety of sulfo compounds in biological systems.	tmpzr1t_l9r_go_relaxed.owl	3'-phosphoadenosine 5'-phosphosulphate metabolism|3'-phosphoadenylyl-sulfate metabolic process|3'-phosphoadenosine 5'-phosphosulphate metabolic process|3'-phosphoadenosine 5'-phosphosulfate metabolism|phosphoadenosine phosphosulfate metabolic process|phosphoadenosine phosphosulfate metabolism|adenosine 3'-phosphate 5'-phosphosulfate metabolic process|PAPS metabolic process|PAPS metabolism|adenosine 3'-phosphate 5'-phosphosulfate metabolism|3'-phosphoadenylyl-sulfate metabolism				MetaCyc:PWY-5340									biological_process											owl:Class	
GO:0010533	biolink:NamedThing	regulation of activation of Janus kinase activity	Any process that modulates the frequency or rate of activation of JAK (Janus Activated Kinase) protein. The activation of JAK protein is the process of introducing a phosphate group to a tyrosine residue of a JAK (Janus Activated Kinase) protein, thereby activating it.	tmpzr1t_l9r_go_relaxed.owl	regulation of tyrosine phosphorylation of JAK1 protein|regulation of activation of JAK2 protein|regulation of activation of JAK2 kinase activity|regulation of tyrosine phosphorylation of JAK protein|regulation of tyrosine phosphorylation of JAK2 protein|regulation of activation of JAK1 protein|regulation of activation of JAK protein|regulation of activation of JAK1 kinase activity											GO:0010534|GO:0010532		biological_process											owl:Class	
GO:0030174	biolink:NamedThing	regulation of DNA-dependent DNA replication initiation	Any process that modulates the frequency, rate or extent of initiation of DNA-dependent DNA replication; the process in which DNA becomes competent to replicate. In eukaryotes, replication competence is established in early G1 and lost during the ensuing S phase.	tmpzr1t_l9r_go_relaxed.owl	regulation of DNA replication initiation|DNA replication licensing|DNA replication licencing													biological_process											owl:Class	
GO:0005308	biolink:NamedThing	creatine transmembrane transporter activity	Enables the transfer of creatine from one side of a membrane to the other. Creatine is a compound synthesized from the amino acids arginine, glycine, and methionine that occurs in muscle.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1900795	biolink:NamedThing	terrequinone A catabolic process	The chemical reactions and pathways resulting in the breakdown of terrequinone A.	tmpzr1t_l9r_go_relaxed.owl	terrequinone A breakdown|terrequinone A degradation|terrequinone A catabolism							di	2012-06-04T09:45:41Z					biological_process											owl:Class	
GO:0009424	biolink:NamedThing	bacterial-type flagellum hook	The portion of the bacterial-type flagellum that connects the filament to the basal body.	tmpzr1t_l9r_go_relaxed.owl	flagellin-based flagellum hook|flagellar hook													cellular_component											owl:Class	
GO:0075137	biolink:NamedThing	response to host redox environment	Any process that results in a change in state or activity of the symbiont organism or its cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detecting the redox environment in host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	response of symbiont to host redox environment					Note that this term is used to annotate gene products of the symbiont.								biological_process											owl:Class	
GO:0080126	biolink:NamedThing	ovary septum development	The process whose specific outcome is the progression of the ovary septum over time, from its formation to the mature structure. The ovary septum is the thin partition that divides the ovary, the basal portion of a carpel or group of fused carpels, that encloses the ovule(s).	tmpzr1t_l9r_go_relaxed.owl								dhl	2009-04-28T04:34:39Z					biological_process											owl:Class	
GO:1905328	biolink:NamedThing	plant septum development	The process whose specific outcome is the progression of a septum over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl	dissepiment development							tb	2016-07-21T18:25:49Z					biological_process											owl:Class	
GO:0030155	biolink:NamedThing	regulation of cell adhesion	Any process that modulates the frequency, rate or extent of attachment of a cell to another cell or to the extracellular matrix.	tmpzr1t_l9r_go_relaxed.owl	cell adhesion receptor regulator activity													biological_process											owl:Class	
GO:0035036	biolink:NamedThing	sperm-egg recognition	The initial contact step made between the sperm plasma membrane and outer layer of the egg during fertilization.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0008949	biolink:NamedThing	oxalyl-CoA decarboxylase activity	Catalysis of the reaction: H(+) + oxalyl-CoA = CO(2) + formyl-CoA.	tmpzr1t_l9r_go_relaxed.owl	oxalyl-CoA carboxy-lyase (formyl-CoA-forming)|oxalyl coenzyme A decarboxylase activity|oxalyl-CoA carboxy-lyase activity				KEGG_REACTION:R01908|EC:4.1.1.8|MetaCyc:OXALYL-COA-DECARBOXYLASE-RXN|RHEA:19333									molecular_function											owl:Class	
GO:0090155	biolink:NamedThing	negative regulation of sphingolipid biosynthetic process	Any process that decreases the rate, frequency or extent of sphingolipid biosynthesis. Sphingolipid biosynthesis is the chemical reactions and pathways resulting in the formation of sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid).	tmpzr1t_l9r_go_relaxed.owl	negative regulation of sphingolipid biosynthesis involved in cellular sphingolipid homeostasis							tb	2009-12-08T03:33:39Z			GO:0090157		biological_process											owl:Class	
GO:0032679	biolink:NamedThing	regulation of TRAIL production	Any process that modulates the frequency, rate, or extent of TRAIL production.	tmpzr1t_l9r_go_relaxed.owl	regulation of TRAIL biosynthetic process											GO:0045554		biological_process											owl:Class	
GO:0043531	biolink:NamedThing	ADP binding	Binding to ADP, adenosine 5'-diphosphate.	tmpzr1t_l9r_go_relaxed.owl	adenosine diphosphate binding|adenosine 5'-diphosphate binding													molecular_function											owl:Class	
GO:0102090	biolink:NamedThing	adrenaline O-methyltransferase activity	Catalysis of the reaction: (R)-adrenaline(1+) + S-adenosyl-L-methionine  <=> metanephrine + S-adenosyl-L-homocysteine + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-10909									molecular_function											owl:Class	
GO:0047733	biolink:NamedThing	CDP-glucose 4,6-dehydratase activity	Catalysis of the reaction: CDP-D-glucose = CDP-4-dehydro-6-deoxy-D-glucose + H(2)O.	tmpzr1t_l9r_go_relaxed.owl	CDPglucose 4,6-dehydratase activity|cytidine diphosphoglucose oxidoreductase activity|CDP-glucose 4,6-hydro-lyase (CDP-4-dehydro-6-deoxy-D-glucose-forming)|CDP-glucose 4,6-hydro-lyase activity|CDPglucose 4,6-hydro-lyase activity				RHEA:17153|MetaCyc:CDP-GLUCOSE-46-DEHYDRATASE-RXN|EC:4.2.1.45|KEGG_REACTION:R02426									molecular_function											owl:Class	
GO:0021916	biolink:NamedThing	inductive cell-cell signaling between paraxial mesoderm and motor neuron precursors	Short range signaling between cells of the paraxial mesoderm and motor neuron precursors in the spinal cord that specifies the fate of the motor column neuron precursors along the anterior-posterior axis.	tmpzr1t_l9r_go_relaxed.owl	inductive cell-cell signalling between paraxial mesoderm and motor neuron precursors													biological_process											owl:Class	
GO:0031129	biolink:NamedThing	inductive cell-cell signaling	Signaling at short range between cells of different ancestry and developmental potential that results in one cell or group of cells effecting a developmental change in the other. This is often done by secretion of proteins by one cell which affects the neighboring cells and causes them to adopt a certain fate.	tmpzr1t_l9r_go_relaxed.owl	inductive cell-cell signalling													biological_process											owl:Class	
GO:0061078	biolink:NamedThing	positive regulation of prostaglandin secretion involved in immune response	Any process that activates or increases the frequency, rate or extent of the regulated release of a prostaglandin from a cell and contributes to the immune response.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of prostaglandin secretion during immune response							dph	2010-04-08T01:53:45Z					biological_process											owl:Class	
GO:0014811	biolink:NamedThing	negative regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion	Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle contraction via the regulation of the release of sequestered calcium ion by sarcoplasmic reticulum into cytosol. The sarcoplasmic reticulum is the endoplasmic reticulum of striated muscle, specialised for the sequestration of calcium ions that are released upon receipt of a signal relayed by the T tubules from the neuromuscular junction.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0097206	biolink:NamedThing	nephrocyte filtration	The process by which hemolymph is filtered based on size and charge through a nephrocyte filtration barrier formed by the basement membrane and nephrocyte diaphragm.	tmpzr1t_l9r_go_relaxed.owl								pr	2012-01-03T03:13:31Z					biological_process											owl:Class	
GO:1905600	biolink:NamedThing	regulation of receptor-mediated endocytosis involved in cholesterol transport	Any process that modulates the frequency, rate or extent of receptor-mediated endocytosis involved in cholesterol transport.	tmpzr1t_l9r_go_relaxed.owl	regulation of receptor-mediated endocytosis of low-density lipoprotein involved in cholesterol transport|regulation of receptor-mediated endocytosis of LDL|regulation of receptor-mediated endocytosis involved in intracellular cholesterol transport|regulation of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport							pr	2016-10-26T13:01:45Z					biological_process											owl:Class	
GO:0015732	biolink:NamedThing	prostaglandin transport	The directed movement of prostaglandins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0120057	biolink:NamedThing	regulation of small intestinal transit	Any process that modulates the frequency, rate or extent of any small intestinal transit process, the migration of ingested material along the length of the small intestine.	tmpzr1t_l9r_go_relaxed.owl	regulation of small bowel transit|regulation of small intestine transit							krc	2017-06-13T20:56:46Z					biological_process											owl:Class	
GO:0038096	biolink:NamedThing	Fc-gamma receptor signaling pathway involved in phagocytosis	An Fc-gamma receptor signaling pathway that contributes to the endocytic engulfment of external particulate material by phagocytes.	tmpzr1t_l9r_go_relaxed.owl	IgG-mediated phagocytosis|Fc gamma receptor-dependent phagocytosis|Fc-gamma receptor signalling pathway involved in phagocytosis|Fcgamma receptor-mediated phagocytosis							bf	2012-02-16T05:26:25Z					biological_process											owl:Class	
GO:1900346	biolink:NamedThing	negative regulation of methane biosynthetic process from methanethiol	Any process that stops, prevents or reduces the frequency, rate or extent of methane biosynthetic process from methanethiol.	tmpzr1t_l9r_go_relaxed.owl	down regulation of methane biosynthetic process from methanethiol|downregulation of methane biosynthetic process from methanethiol|inhibition of methane biosynthetic process from methanethiol|down-regulation of methane biosynthetic process from methanethiol							tt	2012-04-06T02:09:58Z					biological_process											owl:Class	
GO:0048086	biolink:NamedThing	negative regulation of developmental pigmentation	Any process that decreases the frequency, rate or extent of the developmental process that results in the deposition of coloring matter in an organism.	tmpzr1t_l9r_go_relaxed.owl	inhibition of pigmentation|downregulation of developmental pigmentation|down-regulation of developmental pigmentation|down regulation of developmental pigmentation													biological_process											owl:Class	
GO:0110032	biolink:NamedThing	positive regulation of G2/MI transition of meiotic cell cycle	Any signalling pathway that activates or increases the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to MI phase of the meiotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl								kmv	2017-07-12T20:40:54Z					biological_process											owl:Class	
GO:0032727	biolink:NamedThing	positive regulation of interferon-alpha production	Any process that activates or increases the frequency, rate, or extent of interferon-alpha production.	tmpzr1t_l9r_go_relaxed.owl	stimulation of interferon-alpha production|activation of interferon-alpha production|upregulation of interferon-alpha production|up-regulation of interferon-alpha production|up regulation of interferon-alpha production|positive regulation of interferon-alpha secretion|positive regulation of interferon-alpha biosynthetic process											GO:0045356|GO:1902741		biological_process											owl:Class	
GO:0005840	biolink:NamedThing	ribosome	An intracellular organelle, about 200 A in diameter, consisting of RNA and protein. It is the site of protein biosynthesis resulting from translation of messenger RNA (mRNA). It consists of two subunits, one large and one small, each containing only protein and RNA. Both the ribosome and its subunits are characterized by their sedimentation coefficients, expressed in Svedberg units (symbol: S). Hence, the prokaryotic ribosome (70S) comprises a large (50S) subunit and a small (30S) subunit, while the eukaryotic ribosome (80S) comprises a large (60S) subunit and a small (40S) subunit. Two sites on the ribosomal large subunit are involved in translation, namely the aminoacyl site (A site) and peptidyl site (P site). Ribosomes from prokaryotes, eukaryotes, mitochondria, and chloroplasts have characteristically distinct ribosomal proteins.	tmpzr1t_l9r_go_relaxed.owl	free ribosome|ribosomal RNA|membrane bound ribosome				Wikipedia:Ribosome|NIF_Subcellular:sao1429207766							GO:0033279		cellular_component											owl:Class	
GO:1901512	biolink:NamedThing	(-)-microperfuranone biosynthetic process	The chemical reactions and pathways resulting in the formation of (-)-microperfuranone.	tmpzr1t_l9r_go_relaxed.owl	(-)-microperfuranone synthesis|(-)-microperfuranone anabolism|(-)-microperfuranone biosynthesis|(-)-microperfuranone formation							di	2012-10-18T06:54:18Z					biological_process											owl:Class	
GO:0034800	biolink:NamedThing	trinitrophenol dihydride denitratase activity	Catalysis of the reaction: trinitrophenol dihydride Meisenheimer complex (aci form) = 2,4-dinitrophenol hydride Meisenheimer complex + NO2. Trinitrophenol is also known as TNP and dinitrophenol is also known as DNP.	tmpzr1t_l9r_go_relaxed.owl	TNP dihydride denitratase activity|2,4,6-trinitrophenol dihydride denitratase activity				UM-BBD_reactionID:r1067|EC:1.7.99.-									molecular_function											owl:Class	
GO:0021589	biolink:NamedThing	cerebellum structural organization	The process that contributes to the act of creating the structural organization of the cerebellum. This process pertains to the physical shaping of a rudimentary structure. The cerebellum is the portion of the brain in the back of the head between the cerebrum and the pons. The cerebellum controls balance for walking and standing, modulates the force and range of movement and is involved in the learning of motor skills.	tmpzr1t_l9r_go_relaxed.owl	cerebellum structural organisation													biological_process											owl:Class	
GO:0090397	biolink:NamedThing	stigma papilla	A plant cell papilla that is part of a stigma papilla cell.	tmpzr1t_l9r_go_relaxed.owl						Part of stigma papilla cell (PO:0025168).		tb	2010-12-15T03:26:20Z					cellular_component											owl:Class	
GO:0090395	biolink:NamedThing	plant cell papilla	A cell projection that is a short, rounded projection from a plant epidermal cell.	tmpzr1t_l9r_go_relaxed.owl						Part of papilla cell (PO:0025166), which is a shoot epidermal cell (PO:0025165) in plants. Replaces the obsolete term papillae (PO:0002001).		tb	2010-12-15T03:26:20Z					cellular_component											owl:Class	
GO:0015517	biolink:NamedThing	galactose:proton symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: galactose(out) + H+(out) = galactose(in) + H+(in).	tmpzr1t_l9r_go_relaxed.owl	galactose:hydrogen symporter activity|lactose, galactose:hydrogen symporter activity													molecular_function											owl:Class	
GO:0005354	biolink:NamedThing	galactose transmembrane transporter activity	Enables the transfer of galactose from one side of a membrane to the other. D-galactose is widely distributed in combined form in plants, animals and microorganisms as a constituent of oligo- and polysaccharides; it also occurs in galactolipids and as its glucoside in lactose and melibiose.	tmpzr1t_l9r_go_relaxed.owl	galactose/glucose (methylgalactoside) porter activity													molecular_function											owl:Class	
GO:0045258	biolink:NamedThing	plasma membrane succinate dehydrogenase complex (ubiquinone)	The enzyme, located in the plasma membrane, that catalyzes the oxidation of succinate and ubiquinone to fumarate and ubiquinol; involved in aerobic respiration, repressed in anaerobic respiration.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0045257	biolink:NamedThing	succinate dehydrogenase complex (ubiquinone)	The enzyme that catalyzes the oxidation of succinate and ubiquinone to fumarate and ubiquinol; involved in aerobic respiration, repressed in anaerobic respiration.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:1905063	biolink:NamedThing	regulation of vascular associated smooth muscle cell differentiation	Any process that modulates the frequency, rate or extent of vascular smooth muscle cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	regulation of VSMC differentiation|regulation of vascular smooth muscle cell differentiation							rph	2016-03-21T11:14:53Z					biological_process											owl:Class	
GO:0062195	biolink:NamedThing	microtubule bundle maintenance	The organization process that preserves a microtubule bundle in a stable functional or structural state.	tmpzr1t_l9r_go_relaxed.owl								dph	2019-12-09T19:10:30Z					biological_process											owl:Class	
GO:2000673	biolink:NamedThing	positive regulation of motor neuron apoptotic process	Any process that activates or increases the frequency, rate or extent of motor neuron apoptotic process.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of motoneuron apoptosis|positive regulation of motor neuron apoptosis							pr	2011-05-09T10:56:24Z					biological_process											owl:Class	
GO:2001237	biolink:NamedThing	negative regulation of extrinsic apoptotic signaling pathway	Any process that stops, prevents or reduces the frequency, rate or extent of extrinsic apoptotic signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of extrinsic apoptosis|negative regulation of extrinsic apoptotic signalling pathway							pr	2011-11-24T01:30:11Z					biological_process											owl:Class	
GO:2001234	biolink:NamedThing	negative regulation of apoptotic signaling pathway	Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of apoptotic signalling pathway							pr	2011-11-24T01:20:54Z					biological_process											owl:Class	
GO:0106327	biolink:NamedThing	acetylgalactosaminyl-O-glycosyl-threonyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity	Catalysis of the reaction: 3-O-[N-acetyl-alpha-D-galactosaminyl]-L-threonyl-[protein] + UDP-N-acetyl-alpha-D-glucosamine = 3-O-[N-acetyl-beta-D-glucosaminyl-(1->3)-N-acetyl-alpha-D-galactosaminyl]-L-threonyl-[protein] + H(+) + UDP.	tmpzr1t_l9r_go_relaxed.owl					EC:2.4.1.147|RHEA:46880			hjd	2020-09-30T13:44:42Z					molecular_function											owl:Class	
GO:0055024	biolink:NamedThing	regulation of cardiac muscle tissue development	Any process that modulates the frequency, rate or extent of cardiac muscle tissue development.	tmpzr1t_l9r_go_relaxed.owl	regulation of heart muscle development													biological_process											owl:Class	
GO:1901057	biolink:NamedThing	trimethylenediamine biosynthetic process	The chemical reactions and pathways resulting in the formation of trimethylenediamine.	tmpzr1t_l9r_go_relaxed.owl	trimethylenediamine biosynthesis|trimethylenediamine synthesis|trimethylenediamine anabolism|trimethylenediamine formation							yaf	2012-06-28T04:53:14Z					biological_process											owl:Class	
GO:1901055	biolink:NamedThing	trimethylenediamine metabolic process	The chemical reactions and pathways involving trimethylenediamine.	tmpzr1t_l9r_go_relaxed.owl	trimethylenediamine metabolism							yaf	2012-06-28T04:52:42Z					biological_process											owl:Class	
GO:0106300	biolink:NamedThing	protein-DNA covalent cross-linking repair	The removal of covalent cross-link between DNA and a protein.	tmpzr1t_l9r_go_relaxed.owl	resolution of protein-DNA covalent cross-linking							hjd	2020-08-26T14:23:42Z					biological_process											owl:Class	
GO:2000306	biolink:NamedThing	positive regulation of photomorphogenesis	Any process that activates or increases the frequency, rate or extent of photomorphogenesis.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of plant development in response to light							dhl	2011-01-12T07:09:02Z					biological_process											owl:Class	
GO:0042641	biolink:NamedThing	actomyosin	Any complex of actin, myosin, and accessory proteins.	tmpzr1t_l9r_go_relaxed.owl	actomyosin complex|actomyosin structure													cellular_component											owl:Class	
GO:0019557	biolink:NamedThing	histidine catabolic process to glutamate and formate	The chemical reactions and pathways resulting in the breakdown of histidine into other compounds, including glutamate and formate.	tmpzr1t_l9r_go_relaxed.owl	histidine breakdown to glutamate and formate|histidine degradation to glutamate and formate													biological_process											owl:Class	
GO:0047917	biolink:NamedThing	GDP-glucosidase activity	Catalysis of the reaction: GDP-D-glucose + H(2)O = D-glucose + GDP + H(+).	tmpzr1t_l9r_go_relaxed.owl	guanosine diphosphate D-glucose glucohydrolase activity|GDPglucosidase activity|guanosine diphosphoglucosidase activity|GDP-glucose glucohydrolase activity|GDPglucose glucohydrolase activity				EC:3.2.1.42|MetaCyc:GDP-GLUCOSIDASE-RXN|KEGG_REACTION:R00337|RHEA:15049									molecular_function											owl:Class	
GO:2000643	biolink:NamedThing	positive regulation of early endosome to late endosome transport	Any process that activates or increases the frequency, rate or extent of early endosome to late endosome transport.	tmpzr1t_l9r_go_relaxed.owl								vk	2011-04-21T11:20:09Z					biological_process											owl:Class	
GO:0033911	biolink:NamedThing	mycodextranase activity	Catalysis of the endohydrolysis of 1,4-alpha-D-glucosidic linkages in alpha-D-glucans containing both 1,3- and 1,4-bonds.	tmpzr1t_l9r_go_relaxed.owl	1,3-1,4-alpha-D-glucan 4-glucanohydrolase activity				EC:3.2.1.61|MetaCyc:3.2.1.61-RXN									molecular_function											owl:Class	
GO:1902012	biolink:NamedThing	poly(ribitol phosphate) teichoic acid biosynthetic process	The chemical reactions and pathways resulting in the formation of poly(ribitol phosphate) teichoic acid.	tmpzr1t_l9r_go_relaxed.owl	poly(ribitol phosphate) teichoic acid anabolism|poly(ribitol phosphate) teichoic acid formation|poly(ribitol phosphate) teichoic acid biosynthesis|poly(ribitol phosphate) teichoic acid synthesis							tb	2013-03-22T15:43:40Z					biological_process											owl:Class	
GO:0001922	biolink:NamedThing	B-1 B cell homeostasis	The process of regulating the proliferation and elimination of B cells of the B-1 subset such that the total number of B-1 B cells within a whole or part of an organism is stable over time in the absence of an outside stimulus. B-1 B cells are a distinct subset of B cells characterized as being CD5 positive, found predominantly in the peritoneum, pleural cavities, and spleen, and enriched for self-reactivity.	tmpzr1t_l9r_go_relaxed.owl	B-1 B-lymphocyte homeostasis|B-1 B-cell homeostasis|B-1 B lymphocyte homeostasis					Note that this term represents the return of B-1 B cell levels to stable numbers following an immune response, as well as the proliferation and elimination of B-1 B cells in a organism required to maintain stable numbers in the absence of an outside stimulus.								biological_process											owl:Class	
GO:0001782	biolink:NamedThing	B cell homeostasis	The process of regulating the proliferation and elimination of B cells such that the total number of B cells within a whole or part of an organism is stable over time in the absence of an outside stimulus.	tmpzr1t_l9r_go_relaxed.owl	B lymphocyte homeostasis|B-lymphocyte homeostasis|B-cell homeostasis					Note that this term represents the return of B cell levels to stable numbers following an immune response as well as the proliferation and elimination of B cells required to maintain stable numbers in the absence of an outside stimulus.								biological_process											owl:Class	
GO:0072501	biolink:NamedThing	cellular divalent inorganic anion homeostasis	Any process involved in the maintenance of an internal steady state of divalent inorganic anions at the level of a cell.	tmpzr1t_l9r_go_relaxed.owl						Note that this term was split from 'cellular di-, tri-valent inorganic anion homeostasis ; GO:0030319' (sibling term 'cellular trivalent inorganic anion homeostasis' ; GO:0072502').		mah	2010-12-16T12:53:05Z					biological_process											owl:Class	
GO:0051165	biolink:NamedThing	2,5-dihydroxypyridine metabolic process	The chemical reactions and pathways involving 2,5-dihydroxypyridine.	tmpzr1t_l9r_go_relaxed.owl	2,5-dihydroxypyridine metabolism|pyridine-2,5-diol metabolic process													biological_process											owl:Class	
GO:1901342	biolink:NamedThing	regulation of vasculature development	Any process that modulates the frequency, rate or extent of vasculature development.	tmpzr1t_l9r_go_relaxed.owl	regulation of vascular system development							bf	2012-09-06T09:16:15Z					biological_process											owl:Class	
GO:1900012	biolink:NamedThing	positive regulation of corticotropin-releasing hormone receptor activity	Any process that activates or increases the frequency, rate or extent of corticotropin-releasing hormone receptor activity.	tmpzr1t_l9r_go_relaxed.owl	up regulation of CRF receptor activity|positive regulation of corticotropin-releasing factor receptor activity|up regulation of corticotropin-releasing hormone receptor activity|positive regulation of CRF receptor activity|up regulation of CRH receptor activity|up regulation of adrenocorticotropin-releasing hormone receptor activity|up regulation of corticotropin-releasing factor receptor activity|positive regulation of CRH receptor activity|positive regulation of adrenocorticotropin-releasing hormone receptor activity							pr	2012-01-10T02:27:30Z					biological_process											owl:Class	
GO:0150093	biolink:NamedThing	amyloid-beta clearance by transcytosis	The process in which amyloid-beta is removed from extracellular brain regions by cell surface receptor-mediated endocytosis, followed by transcytosis across the blood-brain barrier.	tmpzr1t_l9r_go_relaxed.owl								bc	2018-08-16T14:33:47Z					biological_process											owl:Class	
GO:0097242	biolink:NamedThing	amyloid-beta clearance	The process in which amyloid-beta is removed from extracellular brain regions by mechanisms involving cell surface receptors.	tmpzr1t_l9r_go_relaxed.owl	beta-amyloid clearance							pr	2012-02-16T05:32:29Z					biological_process											owl:Class	
GO:0009422	biolink:NamedThing	bacterial-type flagellum hook-filament junction	The region of the bacterial-type flagellum where the hook and filament meet.	tmpzr1t_l9r_go_relaxed.owl	flagellar hook-filament junction													cellular_component											owl:Class	
GO:0072707	biolink:NamedThing	cellular response to sodium dodecyl sulfate	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sodium dodecyl sulfate (SDS) stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to SDS							mah	2012-04-11T03:35:15Z					biological_process											owl:Class	
GO:1901947	biolink:NamedThing	5alpha,9alpha,10beta-labda-8(20),13-dien-15-yl diphosphate metabolic process	The chemical reactions and pathways involving 5alpha,9alpha,10beta-labda-8(20),13-dien-15-yl diphosphate.	tmpzr1t_l9r_go_relaxed.owl	5alpha,9alpha,10beta-labda-8(20),13-dien-15-yl diphosphate metabolism							ms	2013-02-18T15:50:41Z					biological_process											owl:Class	
GO:0062051	biolink:NamedThing	lipopolysaccharide transport system	A protein-containing complex that functions to transport lipopolysaccharide from its site of synthesis at the cytoplasmic membrane across the periplasm to the outer membrane in an ATP-dependent manner.	tmpzr1t_l9r_go_relaxed.owl								dph	2018-06-04T18:44:40Z					cellular_component											owl:Class	
GO:0050169	biolink:NamedThing	peptide-tryptophan 2,3-dioxygenase activity	Catalysis of the reaction: peptide tryptophan + O2 = peptide formylkynurenine.	tmpzr1t_l9r_go_relaxed.owl	peptide-tryptophan:oxygen 2,3-oxidoreductase (decyclizing)|tryptophan pyrrolooxygenase activity|pyrrolooxygenase activity|peptidyltryptophan 2,3-dioxygenase activity				MetaCyc:PEPTIDE-TRYPTOPHAN-23-DIOXYGENASE-RXN|EC:1.13.11.26									molecular_function											owl:Class	
GO:0046290	biolink:NamedThing	isoflavonoid phytoalexin catabolic process	The chemical reactions and pathways resulting in the breakdown of isoflavonoid phytoalexins, a group of water-soluble phenolic derivatives isomeric with flavonoids that possess antibiotic activity and are produced by plant tissues in response to infection.	tmpzr1t_l9r_go_relaxed.owl	isoflavonoid phytoalexin catabolism|isoflavonoid phytoalexin degradation|isoflavonoid phytoalexin breakdown													biological_process											owl:Class	
GO:0052316	biolink:NamedThing	phytoalexin catabolic process	The chemical reactions and pathways resulting in the breakdown of phytoalexins, any of a range of substances produced by plants as part of their defense response.	tmpzr1t_l9r_go_relaxed.owl	phytoalexin catabolism													biological_process											owl:Class	
GO:1903287	biolink:NamedThing	negative regulation of potassium ion import across plasma membrane	Any process that stops, prevents or reduces the frequency, rate or extent of potassium ion import across the plasma membrane.	tmpzr1t_l9r_go_relaxed.owl	down regulation of potassium ion uptake|downregulation of potassium import|down regulation of potassium ion import|negative regulation of potassium ion uptake|down regulation of potassium import|downregulation of potassium ion import|inhibition of potassium import|down-regulation of potassium ion import|negative regulation of potassium ion import|inhibition of potassium ion import|downregulation of potassium ion uptake|negative regulation of potassium import|down-regulation of potassium ion uptake|inhibition of potassium ion uptake|down-regulation of potassium import							rl	2014-08-11T14:26:24Z					biological_process											owl:Class	
GO:0014705	biolink:NamedThing	C zone	A region of the A band in which myosin-binding protein C is located and that can be seen by electron microscopy. This is a functional zone that also includes myosin.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0050938	biolink:NamedThing	regulation of xanthophore differentiation	Any process that modulates the frequency, rate or extent of xanthophore differentiation.	tmpzr1t_l9r_go_relaxed.owl						Note that this term refers to xanthophores in the sense of specialized pigment-producing cells, and should not be confused with the cellular component term 'xanthophore ; GO:0031633', which refers to a subcellular structure.								biological_process											owl:Class	
GO:0019099	biolink:NamedThing	female germ-line sex determination	The determination of sex and sexual phenotype in a female organism's germ line.	tmpzr1t_l9r_go_relaxed.owl	sex determination, female germ-line determination											GO:0007544		biological_process											owl:Class	
GO:0003859	biolink:NamedThing	3-hydroxybutyryl-CoA dehydratase activity	Catalysis of the reaction: (R)-3-hydroxybutanoyl-CoA = crotonoyl-CoA + H(2)O.	tmpzr1t_l9r_go_relaxed.owl	(3R)-3-hydroxybutanoyl-CoA hydro-lyase (crotonoyl-CoA-forming)|enoyl coenzyme A hydrase (D)|D-3-hydroxybutyryl coenzyme A dehydratase activity|D-3-hydroxybutyryl-CoA dehydratase activity|crotonase activity|(3R)-3-hydroxybutanoyl-CoA hydro-lyase activity				KEGG_REACTION:R03027|RHEA:17849|EC:4.2.1.55|MetaCyc:3-HYDROXBUTYRYL-COA-DEHYDRATASE-RXN									molecular_function											owl:Class	
GO:1903534	biolink:NamedThing	regulation of lactose biosynthetic process	Any process that modulates the frequency, rate or extent of lactose biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of lactose synthesis|regulation of lactose anabolism|regulation of lactose formation|regulation of lactose biosynthesis							mr	2014-10-08T16:26:05Z					biological_process											owl:Class	
GO:1904754	biolink:NamedThing	positive regulation of vascular associated smooth muscle cell migration	Any process that activates or increases the frequency, rate or extent of vascular associated smooth muscle cell migration.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of vascular smooth muscle cell migration|upregulation of vascular smooth muscle cell migration|up regulation of vascular smooth muscle cell migration|up-regulation of vascular associated smooth muscle cell migration|up-regulation of vascular smooth muscle cell migration|upregulation of vascular associated smooth muscle cell migration|up regulation of vascular associated smooth muscle cell migration|activation of vascular associated smooth muscle cell migration|activation of vascular smooth muscle cell migration							rph	2015-10-19T15:50:05Z					biological_process											owl:Class	
GO:0014911	biolink:NamedThing	positive regulation of smooth muscle cell migration	Any process that activates, maintains or increases the frequency, rate or extent of smooth muscle cell migration.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0060265	biolink:NamedThing	positive regulation of respiratory burst involved in inflammatory response	Any process that increases the rate, frequency or extent of a phase of elevated metabolic activity, during which oxygen consumption increases made as a defense response ; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of respiratory burst involved in acute inflammatory response													biological_process											owl:Class	
GO:0102099	biolink:NamedThing	FAD-dependent urate hydroxylase activity	Catalysis of the reaction: 7,9-dihydro-1H-purine-2,6,8(3H)-trione + NADH + H+ + O2 <=> 5-hydroxyisouric acid + NAD + H2O.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-11186|RHEA:27329|EC:1.14.13.113									molecular_function											owl:Class	
GO:1901238	biolink:NamedThing	ABC-type tungstate transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + tungstate(in) = ADP + phosphate + tungstate(out).	tmpzr1t_l9r_go_relaxed.owl	tungstate transmembrane transporter activity|tungstate transmembrane-transporting ATPase activity|ATPase-coupled tungstate transmembrane transporter activity				RHEA:35027|EC:7.3.2.6			jl	2012-08-07T14:47:36Z			GO:1901237		molecular_function											owl:Class	
GO:0060011	biolink:NamedThing	Sertoli cell proliferation	The multiplication or reproduction of Sertoli cells, resulting in the expansion of the Sertoli cell population. A Sertoli cell is a supporting cell projecting inward from the basement membrane of seminiferous tubules.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:2000486	biolink:NamedThing	negative regulation of glutamine transport	Any process that stops, prevents or reduces the frequency, rate or extent of glutamine transport.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of L-glutamine transport							bf	2011-03-11T09:33:07Z					biological_process											owl:Class	
GO:0002853	biolink:NamedThing	negative regulation of T cell mediated cytotoxicity directed against tumor cell target	Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell mediated cytotoxicity directed against a tumor cell target.	tmpzr1t_l9r_go_relaxed.owl	inhibition of T cell mediated cytotoxicity directed against tumor cell target|down-regulation of T cell mediated cytotoxicity directed against tumor cell target|down regulation of T cell mediated cytotoxicity directed against tumor cell target|downregulation of T cell mediated cytotoxicity directed against tumor cell target													biological_process											owl:Class	
GO:0002841	biolink:NamedThing	negative regulation of T cell mediated immune response to tumor cell	Any process that stops, prevents, or reduces the frequency, rate, or extent of a T cell mediated immune response to tumor cell.	tmpzr1t_l9r_go_relaxed.owl	down regulation of T cell mediated immune response to tumor cell|negative regulation of T lymphocyte mediated immune response to tumor cell|downregulation of T cell mediated immune response to tumor cell|negative regulation of T cell mediated immune response to tumour cell|negative regulation of T-cell mediated immune response to tumor cell|down-regulation of T cell mediated immune response to tumor cell|inhibition of T cell mediated immune response to tumor cell|negative regulation of T-lymphocyte mediated immune response to tumor cell													biological_process											owl:Class	
GO:1902699	biolink:NamedThing	pentose catabolic process to acetate	The chemical reactions and pathways resulting in the breakdown of pentose to acetate.	tmpzr1t_l9r_go_relaxed.owl	pentose degradation to acetate|pentose breakdown to acetate|acidogenesis|pentose catabolism to acetate							tb	2014-02-19T18:28:38Z			GO:1990289		biological_process											owl:Class	
GO:0051891	biolink:NamedThing	positive regulation of cardioblast differentiation	Any process that activates or increases the frequency, rate or extent of cardioblast differentiation, the process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of cardioblast differentiation|up regulation of cardioblast differentiation|activation of cardioblast differentiation|stimulation of cardioblast differentiation|upregulation of cardioblast differentiation													biological_process											owl:Class	
GO:0072325	biolink:NamedThing	vulval cell fate commitment	The process in which the cellular identity of nematode vulval cells is acquired and determined. In nematodes, the vulva is formed from ventral epidermal cells during larval stages to give rise to a fully formed adult vulva, which is the egg-laying organ of female and hermaphrodite nematodes.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-11-01T02:02:16Z					biological_process											owl:Class	
GO:0051759	biolink:NamedThing	sister chromosome movement towards spindle pole involved in meiotic sister chromatid segregation	The directed movement of sister chromosomes from the center of the spindle towards the spindle poles, mediated by the shortening of microtubules attached to the chromosomes, during meiosis II.	tmpzr1t_l9r_go_relaxed.owl	meiosis II, sister chromosome movement towards spindle pole|sister chromosome movement towards spindle pole during meiosis II													biological_process											owl:Class	
GO:1904798	biolink:NamedThing	positive regulation of core promoter binding	Any process that activates or increases the frequency, rate or extent of core promoter binding.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of core promoter binding|up regulation of core promoter binding|upregulation of core promoter binding|activation of core promoter binding							nc	2015-11-09T12:32:38Z					biological_process											owl:Class	
GO:0019755	biolink:NamedThing	one-carbon compound transport	The directed movement of one-carbon compounds into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	one carbon compound transport													biological_process											owl:Class	
GO:1901713	biolink:NamedThing	negative regulation of urea catabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of urea catabolic process.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of urea decomposition|down-regulation of urea catabolic process|down regulation of urea catabolic process|down regulation of urea decomposition|inhibition of urea degradation|down regulation of urea catabolism|inhibition of urea catabolism|inhibition of urea decomposition|downregulation of urea catabolic process|down-regulation of urea breakdown|down-regulation of urea decomposition|down regulation of urea breakdown|negative regulation of urea degradation|inhibition of urea breakdown|inhibition of urea catabolic process|down-regulation of urea catabolism|negative regulation of urea catabolism|down-regulation of urea degradation|downregulation of urea decomposition|down regulation of urea degradation|downregulation of urea breakdown|negative regulation of urea breakdown|downregulation of urea catabolism|downregulation of urea degradation							mcc	2012-12-19T16:12:13Z					biological_process											owl:Class	
GO:2000256	biolink:NamedThing	positive regulation of male germ cell proliferation	Any process that activates or increases the frequency, rate or extent of male germ cell proliferation.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-11-18T09:29:50Z					biological_process											owl:Class	
GO:0044775	biolink:NamedThing	DNA polymerase III, beta sliding clamp processivity factor complex	A subcomplex of the DNA polymerase III holoenzyme which is responsible for tethering the catalytic subunit of DNA polymerase to DNA during high-speed replication. The complex is homodimeric in prokaryotes, and homotrimeric in other species.	tmpzr1t_l9r_go_relaxed.owl								jl	2013-03-13T13:59:48Z					cellular_component											owl:Class	
GO:0044796	biolink:NamedThing	DNA polymerase processivity factor complex	A protein complex which is capable of increasing the processivity of nucleotide polymerization by DNA polymerase as a part of DNA replication.	tmpzr1t_l9r_go_relaxed.owl								jl	2013-08-28T11:16:14Z					cellular_component											owl:Class	
GO:1903090	biolink:NamedThing	pyridoxal transmembrane transport	The process in which pyridoxal is transported across a membrane.	tmpzr1t_l9r_go_relaxed.owl								al	2014-06-03T10:41:13Z					biological_process											owl:Class	
GO:0035461	biolink:NamedThing	vitamin transmembrane transport	The process in which a vitamin is transported across a membrane. A vitamin is one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body.	tmpzr1t_l9r_go_relaxed.owl	vitamin membrane transport					Note that this term is not intended for use in annotating lateral movement within membranes.		bf	2010-04-19T10:21:41Z					biological_process											owl:Class	
GO:0002199	biolink:NamedThing	zona pellucida receptor complex	A multisubunit complex comprising the chaperonin-containing T-complex and several other components involved in mediating sperm-oocyte Interaction.	tmpzr1t_l9r_go_relaxed.owl	sperm protein complex I							hjd	2011-12-23T01:33:23Z					cellular_component											owl:Class	
GO:1901352	biolink:NamedThing	negative regulation of phosphatidylglycerol biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of phosphatidylglycerol biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	downregulation of phosphatidylglycerol anabolism|down regulation of phosphatidylglycerol biosynthesis|downregulation of phosphatidylglycerol synthesis|down-regulation of phosphatidylglycerol formation|negative regulation of phosphatidylglycerol biosynthesis|inhibition of phosphatidylglycerol anabolism|down regulation of phosphatidylglycerol synthesis|inhibition of phosphatidylglycerol biosynthesis|inhibition of phosphatidylglycerol synthesis|negative regulation of phosphatidylglycerol formation|down regulation of phosphatidylglycerol formation|down-regulation of phosphatidylglycerol biosynthetic process|downregulation of phosphatidylglycerol biosynthesis|negative regulation of phosphatidylglycerol synthesis|down-regulation of phosphatidylglycerol synthesis|downregulation of phosphatidylglycerol biosynthetic process|inhibition of phosphatidylglycerol biosynthetic process|down-regulation of phosphatidylglycerol biosynthesis|negative regulation of phosphatidylglycerol anabolism|downregulation of phosphatidylglycerol formation|down regulation of phosphatidylglycerol biosynthetic process|down-regulation of phosphatidylglycerol anabolism|down regulation of phosphatidylglycerol anabolism|inhibition of phosphatidylglycerol formation							dgf	2012-09-12T20:47:53Z					biological_process											owl:Class	
GO:1902785	biolink:NamedThing	cellular response to undecane	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an undecane stimulus.	tmpzr1t_l9r_go_relaxed.owl								tt	2014-03-21T13:39:24Z					biological_process											owl:Class	
GO:0030578	biolink:NamedThing	PML body organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of PML bodies, a class of nuclear body; they react against SP100 auto-antibodies (PML = promyelocytic leukemia).	tmpzr1t_l9r_go_relaxed.owl	PML body organisation|PML body organization and biogenesis					See also the cellular component term 'PML body ; GO:0016605'.								biological_process											owl:Class	
GO:0035519	biolink:NamedThing	protein K29-linked ubiquitination	A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 29 of the ubiquitin monomers, is added to a protein. K29-linked ubiquitination targets the substrate protein for degradation.	tmpzr1t_l9r_go_relaxed.owl	protein K29-linked polyubiquitination							bf	2010-05-04T04:25:48Z					biological_process											owl:Class	
GO:0032259	biolink:NamedThing	methylation	The process in which a methyl group is covalently attached to a molecule.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Methylation									biological_process											owl:Class	
GO:1905699	biolink:NamedThing	regulation of xenobiotic detoxification by transmembrane export across the plasma membrane	Any process that modulates the frequency, rate or extent of xenobiotic transmembrane export. A xenobiotic is a compound foreign to the organim exposed to it. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical.	tmpzr1t_l9r_go_relaxed.owl	regulation of drug transmembrane export|regulation of xenobiotic transmembrane export	https://github.com/geneontology/go-ontology/issues/19460|https://github.com/geneontology/go-ontology/issues/17083						sl	2016-11-15T16:46:28Z					biological_process											owl:Class	
GO:1990673	biolink:NamedThing	intrinsic component of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane	The component of the ERGIC membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.	tmpzr1t_l9r_go_relaxed.owl	intrinsic component of endoplasmic reticulum-Golgi intermediate compartment membrane							bhm	2015-03-02T11:44:46Z					cellular_component											owl:Class	
GO:0045989	biolink:NamedThing	positive regulation of striated muscle contraction	Any process that activates or increases the frequency, rate or extent of striated muscle contraction.	tmpzr1t_l9r_go_relaxed.owl	up regulation of striated muscle contraction|stimulation of striated muscle contraction|activation of striated muscle contraction|up-regulation of striated muscle contraction|upregulation of striated muscle contraction													biological_process											owl:Class	
GO:0043569	biolink:NamedThing	negative regulation of insulin-like growth factor receptor signaling pathway	Any process that stops, prevents, or reduces the frequency, rate or extent of insulin-like growth factor receptor signaling.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of IGF receptor signaling pathway|down-regulation of insulin-like growth factor receptor signaling pathway|down regulation of insulin-like growth factor receptor signaling pathway|negative regulation of insulin-like growth factor receptor signalling pathway|downregulation of insulin-like growth factor receptor signaling pathway|negative regulation of IGF receptor signalling pathway|inhibition of insulin-like growth factor receptor signaling pathway													biological_process											owl:Class	
GO:0002083	biolink:NamedThing	4-hydroxybenzoate decaprenyltransferase activity	Catalysis of the reaction: all-trans-decaprenyl diphosphate + 4-hydroxybenzoate = 3-decaprenyl-4-hydroxybenzoate + diphosphate.	tmpzr1t_l9r_go_relaxed.owl					RHEA:44564|MetaCyc:RXN-9230|EC:2.5.1.39|Reactome:R-HSA-2162192									molecular_function											owl:Class	
GO:0046295	biolink:NamedThing	glycolate biosynthetic process	The chemical reactions and pathways resulting in the formation of glycolate, the anion of hydroxyethanoic acid (glycolic acid).	tmpzr1t_l9r_go_relaxed.owl	glycolate formation|glycolate synthesis|glycolate biosynthesis|glycolate anabolism													biological_process											owl:Class	
GO:1905887	biolink:NamedThing	autoinducer AI-2 transmembrane transport	The process in which (2R,4S)-2-methyltetrahydrofuran-2,3,3,4-tetrol (autoinducer AI-2) is transported across a membrane. AI-2 is produced by prokaryotes and is believed to play a role in quorum sensing.	tmpzr1t_l9r_go_relaxed.owl	autoinducer 2 transmembrane transport|(2R,4S)-2-methyltetrahydrofuran-2,3,3,4-tetrol transmembrane transport|AI-2 transmembrane transport							dos	2017-01-31T14:34:50Z					biological_process											owl:Class	
GO:0090626	biolink:NamedThing	plant epidermis morphogenesis	The process in which the anatomical structures of the plant epidermis are generated and organized.	tmpzr1t_l9r_go_relaxed.owl								tb	2015-01-29T14:54:03Z					biological_process											owl:Class	
GO:0110141	biolink:NamedThing	L-glutamate import into mitochondrion	The process in which L-glutamate is transported from the cytosol into the mitochondrial matrix.	tmpzr1t_l9r_go_relaxed.owl								kmv	2019-04-24T19:13:46Z					biological_process											owl:Class	
GO:0044382	biolink:NamedThing	CLRC complex localization to heterochromatin	The process by which a CLRC complex is transported to, or maintained in, heterochromatin. CLRC complex is an active cullin-dependent E3 ubiquitin ligase complex essential for heterochromatin assembly by RNAi and histone H3K9 methylation.	tmpzr1t_l9r_go_relaxed.owl	CLRC ubiquitin ligase complex localisation to heterochromatin|CLRC ubiquitin ligase complex localization to heterochromatin							jl	2011-12-13T03:37:18Z					biological_process											owl:Class	
GO:0039599	biolink:NamedThing	cleavage by virus of host mRNA	Any process in which a host pre-mRNA or mRNA molecule is cleaved at specific sites or in a regulated manner by a viral endoribonuclease.	tmpzr1t_l9r_go_relaxed.owl	viral endoribonuclease activity involved in degradation of host mRNA|host mRNA cleavage by viral endoribonuclease							bf	2012-07-04T05:09:08Z					biological_process											owl:Class	
GO:0033629	biolink:NamedThing	negative regulation of cell adhesion mediated by integrin	Any process that stops, prevents, or reduces the frequency, rate, or extent of cell adhesion mediated by integrin.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of cell adhesion mediated by integrin complex													biological_process											owl:Class	
GO:0099509	biolink:NamedThing	regulation of presynaptic cytosolic calcium ion concentration	Any process that regulates the concentration of calcium in the presynaptic cytosol.	tmpzr1t_l9r_go_relaxed.owl	regulation of presynaptic cytosolic calcium levels													biological_process											owl:Class	
GO:2000935	biolink:NamedThing	positive regulation of cellotriose metabolic process	Any process that activates or increases the frequency, rate or extent of cellotriose metabolic process.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of cellotriose metabolism							tt	2011-08-01T12:44:24Z					biological_process											owl:Class	
GO:0019473	biolink:NamedThing	L-lysine catabolic process to glutarate, by acetylation	The chemical reactions and pathways resulting in the breakdown of L-lysine into other compounds, including glutarate, by acetylation.	tmpzr1t_l9r_go_relaxed.owl	L-lysine breakdown to glutarate, by acetylation|L-lysine degradation to glutarate, by acetylation				MetaCyc:LYSDEGII-PWY									biological_process											owl:Class	
GO:0030228	biolink:NamedThing	lipoprotein particle receptor activity	Combining with a lipoprotein particle and delivering the lipoprotein particle into the cell via endocytosis. A lipoprotein particle, also known as a lipoprotein, is a clathrate complex consisting of a lipid enwrapped in a protein host without covalent binding in such a way that the complex has a hydrophilic outer surface consisting of all the protein and the polar ends of any phospholipids.	tmpzr1t_l9r_go_relaxed.owl	plasma lipoprotein particle receptor activity|lipoprotein receptor activity					This term is intended for cell surface receptors that bind and internalize a lipoprotein particle. For members of the lipoprotein receptor family that transduce a signal rather than endocytose their ligand, consider instead the terms 'signaling receptor activity ; GO:0038023' and its children, or 'reelin receptor activity ; GO:0038025'.								molecular_function											owl:Class	
GO:0021731	biolink:NamedThing	trigeminal motor nucleus development	The process whose specific outcome is the progression of the trigeminal motor nucleus over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0098832	biolink:NamedThing	peri-centrosomal recycling endosome	A recycling endosome that is organized around the microtubule organizing center, close to the nucleus. This is the main recycling endosome of most cells. It receives input from the Golgi as well as recycled molecules from early endosomes.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:1990739	biolink:NamedThing	granulosa cell proliferation	The multiplication or reproduction of granulosa cells, resulting in the expansion of the granulosa cells population. A granulosa cell is a supporting cell for the developing female gamete in the ovary of mammals. They develop from the coelomic epithelial cells of the gonadal ridge.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-05-06T18:56:04Z					biological_process											owl:Class	
GO:0010015	biolink:NamedThing	root morphogenesis	The process in which the anatomical structures of roots are generated and organized. The root is the usually underground part of a seed plant body that originates from the hypocotyl, functions as an organ of absorption, aeration, and food storage or as a means of anchorage and support.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0050463	biolink:NamedThing	nitrate reductase [NAD(P)H] activity	Catalysis of the reaction: nitrite + NAD(P)+ + H2O = nitrate + NAD(P)H + H+.	tmpzr1t_l9r_go_relaxed.owl	assimilatory nitrate reductase activity|nitrite:NAD(P)+ oxidoreductase activity|NAD(P)H2:nitrate oxidoreductase activity|nitrate reductase (reduced nicotinamide adenine dinucleotide (phosphate)) activity|NAD(P)H:nitrate oxidoreductase activity|nitrate reductase NAD(P)H activity|NAD(P)H bispecific nitrate reductase activity|assimilatory NAD(P)H-nitrate reductase activity|nitrate reductase [NAD(P)H2]|NAD(P)H-nitrate reductase activity				EC:1.7.1.2									molecular_function											owl:Class	
GO:0009581	biolink:NamedThing	detection of external stimulus	The series of events in which an external stimulus is received by a cell and converted into a molecular signal.	tmpzr1t_l9r_go_relaxed.owl	perception of external stimulus													biological_process											owl:Class	
GO:0046949	biolink:NamedThing	fatty-acyl-CoA biosynthetic process	The chemical reactions and pathways resulting in the formation of a fatty-acyl-CoA, any derivative of coenzyme A in which the sulfhydryl group is in thiolester linkage with a fatty-acyl group.	tmpzr1t_l9r_go_relaxed.owl	fatty-acyl-CoA formation|fatty-acyl-CoA biosynthesis|fatty-acyl-CoA anabolism|fatty acyl CoA biosynthetic process|fatty-acyl-CoA synthesis													biological_process											owl:Class	
GO:0005146	biolink:NamedThing	leukemia inhibitory factor receptor binding	Binding to an leukemia inhibitory factor receptor.	tmpzr1t_l9r_go_relaxed.owl	leukemia inhibitory factor receptor ligand|leukemia inhibitory factor													molecular_function											owl:Class	
GO:1903184	biolink:NamedThing	L-dopa metabolic process	The chemical reactions and pathways involving L-dopa.	tmpzr1t_l9r_go_relaxed.owl	L-dopa metabolism							bf	2014-07-14T15:06:00Z					biological_process											owl:Class	
GO:0021837	biolink:NamedThing	motogenic signaling involved in postnatal olfactory bulb interneuron migration	The signaling that results in the stimulation of cell movement in the rostral migratory stream.	tmpzr1t_l9r_go_relaxed.owl	motogenic signalling involved in postnatal olfactory bulb interneuron migration													biological_process											owl:Class	
GO:0045684	biolink:NamedThing	positive regulation of epidermis development	Any process that activates or increases the frequency, rate or extent of epidermis development.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of hypodermis development|up-regulation of epidermis development|stimulation of epidermis development|upregulation of epidermis development|positive regulation of epidermal development|up regulation of epidermis development|activation of epidermis development													biological_process											owl:Class	
GO:0004464	biolink:NamedThing	leukotriene-C4 synthase activity	Catalysis of the reaction: leukotriene C(4) = glutathione + leukotriene A(4).	tmpzr1t_l9r_go_relaxed.owl	LTC4 synthase activity|leukotriene A4:glutathione S-leukotrienyltransferase activity|(7E,9E,11Z,14Z)-(5S,6R)-5,6-epoxyicosa-7,9,11,14-tetraenoate:glutathione leukotriene-transferase (epoxide-ring-opening)|leukotriene C(4) synthetase activity|leukotriene A(4):glutathione S-leukotrienyltransferase activity|(7E,9E,11Z,14Z)-(5S,6R)-6-(glutathion-S-yl)-5-hydroxyicosa-7,9,11,14-tetraenoate glutathione-lyase (epoxide-forming)|LTC(4) synthase activity|LTC4 synthetase activity|leukotriene-C4 glutathione-lyase (leukotriene-A4-forming)|LTC(4) synthetase activity|leukotriene C4 synthetase activity				Reactome:R-HSA-266050|RHEA:17617|EC:4.4.1.20|KEGG_REACTION:R03059|MetaCyc:LEUKOTRIENE-C4-SYNTHASE-RXN	Note that this function was EC:2.5.1.37.								molecular_function											owl:Class	
GO:1900519	biolink:NamedThing	negative regulation of response to pullulan	Any process that stops, prevents or reduces the frequency, rate or extent of response to pullulan.	tmpzr1t_l9r_go_relaxed.owl	downregulation of response to pullulan|down-regulation of response to pullulan|down regulation of response to pullulan|inhibition of response to pullulan							tt	2012-05-02T04:12:09Z					biological_process											owl:Class	
GO:0055046	biolink:NamedThing	microgametogenesis	The process whose specific outcome is the progression of the pollen grain over time, from its formation as the microspore to the mature structure.	tmpzr1t_l9r_go_relaxed.owl	pollen development from the microspore				Wikipedia:Microgametogenesis									biological_process											owl:Class	
GO:1901626	biolink:NamedThing	regulation of postsynaptic membrane organization	Any process that modulates the frequency, rate or extent of postsynaptic membrane organization.	tmpzr1t_l9r_go_relaxed.owl	regulation of postsynaptic membrane organisation|regulation of post-synaptic membrane organization							ans	2012-11-15T11:40:15Z					biological_process											owl:Class	
GO:0050107	biolink:NamedThing	monoterpenol O-acetyltransferase activity	Catalysis of the reaction: acetyl-CoA + a monoterpenol = CoA + a monoterpenol acetate ester.	tmpzr1t_l9r_go_relaxed.owl	acetyl-CoA:monoterpenol O-acetyltransferase activity|menthol transacetylase activity				EC:2.3.1.69|MetaCyc:MONOTERPENOL-O-ACETYLTRANSFERASE-RXN									molecular_function											owl:Class	
GO:0035212	biolink:NamedThing	cell competition in a multicellular organism	Competitive interactions within multicellular organisms between cell populations that differ in growth rates, leading to the elimination of the slowest-growing cells.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:2000315	biolink:NamedThing	positive regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation	Any process that activates or increases the frequency, rate or extent of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of fibroblast growth factor receptor signalling pathway involved in neural plate anterior/posterior pattern formation							vk	2011-01-18T10:27:19Z					biological_process											owl:Class	
GO:0097231	biolink:NamedThing	cell motility in response to calcium ion	Any process involved in the controlled self-propelled movement of a cell that results in translocation of the cell from one place to another as a result of a calcium ion stimulus.	tmpzr1t_l9r_go_relaxed.owl	Ca2+ facilitation of cell motility|calcium ion facilitation of cell motility							pr	2012-01-25T04:42:45Z					biological_process											owl:Class	
GO:1901315	biolink:NamedThing	negative regulation of histone H2A K63-linked ubiquitination	Any process that stops, prevents or reduces the frequency, rate or extent of histone H2A K63-linked ubiquitination.	tmpzr1t_l9r_go_relaxed.owl	down regulation of histone H2A K63-linked ubiquitination|inhibition of histone H2A K63-linked ubiquitination|down-regulation of histone H2A K63-linked ubiquitination|downregulation of histone H2A K63-linked ubiquitination							tb	2012-08-22T20:29:24Z					biological_process											owl:Class	
GO:1900283	biolink:NamedThing	negative regulation of cellobiose catabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of cellobiose catabolic process.	tmpzr1t_l9r_go_relaxed.owl	downregulation of cellobiose catabolism|negative regulation of cellobiose catabolism|downregulation of cellobiose catabolic process|inhibition of cellobiose catabolic process|down regulation of cellobiose catabolism|inhibition of cellobiose catabolism|down-regulation of cellobiose catabolism|down-regulation of cellobiose catabolic process|down regulation of cellobiose catabolic process							tt	2012-04-05T12:29:00Z					biological_process											owl:Class	
GO:0099040	biolink:NamedThing	ceramide translocation	The movement of a ceramide molecule from one leaflet of a membrane bilayer to the opposite leaflet.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0099039	biolink:NamedThing	sphingolipid translocation	The movement of a sphingolipid molecule from one leaflet of a membrane bilayer to the opposite leaflet.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:2000150	biolink:NamedThing	regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis	Any process that modulates the frequency, rate or extent of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-10-01T07:11:11Z					biological_process											owl:Class	
GO:0098884	biolink:NamedThing	postsynaptic neurotransmitter receptor internalization	A receptor-mediated endocytosis process that results in the internalization of a neurotransmitter receptor from the postsynaptic membrane endocytic zone into an endocytic vesicle.	tmpzr1t_l9r_go_relaxed.owl	postsynaptic neurotransmitter receptor endocytosis	https://github.com/geneontology/synapse/issues/230												biological_process											owl:Class	
GO:0005787	biolink:NamedThing	signal peptidase complex	A protein complex that is located in the endoplasmic reticulum membrane and cleaves the signal sequence from precursor proteins following their transport out of the cytoplasmic space.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:1900717	biolink:NamedThing	negative regulation of violaceol II biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of violaceol II biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of violaceol II formation|inhibition of violaceol II formation|down-regulation of violaceol II biosynthesis|down-regulation of violaceol II biosynthetic process|inhibition of violaceol II synthesis|downregulation of violaceol II biosynthetic process|downregulation of violaceol II anabolism|inhibition of violaceol II anabolism|down regulation of violaceol II biosynthesis|negative regulation of violaceol II biosynthesis|inhibition of violaceol II biosynthesis|down regulation of violaceol II anabolism|down regulation of violaceol II synthesis|negative regulation of violaceol II synthesis|downregulation of violaceol II synthesis|down regulation of violaceol II biosynthetic process|down regulation of violaceol II formation|down-regulation of violaceol II formation|downregulation of violaceol II biosynthesis|inhibition of violaceol II biosynthetic process|down-regulation of violaceol II anabolism|down-regulation of violaceol II synthesis|downregulation of violaceol II formation|negative regulation of violaceol II anabolism							di	2012-05-22T05:05:58Z					biological_process											owl:Class	
GO:0038151	biolink:NamedThing	CCL2-activated CCR2 signaling pathway	A series of molecular signals initiated by the binding of the C-C chemokine CCL2 to a C-C chemokine type 2 receptor (CCR2) on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.	tmpzr1t_l9r_go_relaxed.owl	CCL2/CCR2 signaling pathway							bf	2012-05-11T11:41:58Z					biological_process											owl:Class	
GO:0004025	biolink:NamedThing	alcohol dehydrogenase activity, iron-dependent	Catalysis of the reaction: an alcohol + NAD+ = an aldehyde or ketone + NADH + H+, requiring the presence of iron.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0004575	biolink:NamedThing	sucrose alpha-glucosidase activity	Catalysis of the reaction: sucrose + H2O = alpha-D-glucose + beta-D-fructose.	tmpzr1t_l9r_go_relaxed.owl	intestinal sucrase activity|sucrase(invertase)|sucrase-isomaltase activity|sucrase activity|beta-D-fructofuranosyl alpha-D-glucopyranoside hydrolysis|sucrose-alpha-D-glucohydrolase activity|sucrose alpha-glucohydrolase activity|sucrose alpha-D-glucohydrolase activity|sucrose hydrolysis|alpha-D-glucopyranosyl beta-D-fructofuranoside hydrolysis				EC:3.2.1.48|RHEA:33795|MetaCyc:RXN-1461|KEGG_REACTION:R00802|Reactome:R-HSA-189069|Reactome:R-HSA-5659926									molecular_function											owl:Class	
GO:0150032	biolink:NamedThing	positive regulation of protein localization to lysosome	Any process that activates or increases the frequency, rate or extent of protein localization to lysosome.	tmpzr1t_l9r_go_relaxed.owl								bc	2018-02-06T17:11:02Z					biological_process											owl:Class	
GO:0014022	biolink:NamedThing	neural plate elongation	The process in which the neural plate is shaped by the intrinsic movement of the epidermal and neural plate regions.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0021820	biolink:NamedThing	extracellular matrix organization in marginal zone involved in cerebral cortex radial glia guided migration	The process that leads to the deposition of extracellular matrix signals in the marginal zone of the developing cerebral cortex. This extracellular matrix controls the movement of migrating cells. In mammals, the matrix is modified by Cajal-Retzius cells.	tmpzr1t_l9r_go_relaxed.owl	organization of extracellular matrix in the marginal zone involved in cerebral cortex glial-mediated radial migration|extracellular matrix organisation in marginal zone involved in cerebral cortex radial glia guided migration													biological_process											owl:Class	
GO:0032363	biolink:NamedThing	FMN catabolic process	The chemical reactions and pathways resulting in the breakdown of FMN, riboflavin 5'-(dihydrogen phosphate), a coenzyme for a number of oxidative enzymes including NADH dehydrogenase.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0070582	biolink:NamedThing	theta DNA replication	A DNA-dependent DNA replication process in which a double-stranded DNA molecule is synthesized from a circular duplex template.	tmpzr1t_l9r_go_relaxed.owl	theta replication							mah	2009-04-22T02:54:50Z					biological_process											owl:Class	
GO:0061562	biolink:NamedThing	cranial ganglion structural organization	The process that contributes to creating the structural organization of a cranial ganglion. This process pertains to the physical shaping of a rudimentary structure.	tmpzr1t_l9r_go_relaxed.owl	cranial ganglia structural organization							dph	2013-07-10T09:10:52Z					biological_process											owl:Class	
GO:0061555	biolink:NamedThing	ganglion structural organization	The process that contributes to creating the structural organization of a ganglion. This process pertains to the physical shaping of a rudimentary structure.	tmpzr1t_l9r_go_relaxed.owl	ganglia structural organization							dph	2013-07-10T08:54:39Z					biological_process											owl:Class	
GO:0032264	biolink:NamedThing	IMP salvage	Any process which produces inosine monophosphate from derivatives of it, without de novo synthesis.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0006188	biolink:NamedThing	IMP biosynthetic process	The chemical reactions and pathways resulting in the formation of IMP, inosine monophosphate.	tmpzr1t_l9r_go_relaxed.owl	IMP formation|IMP biosynthesis|IMP synthesis|IMP anabolism													biological_process											owl:Class	
GO:0002333	biolink:NamedThing	transitional one stage B cell differentiation	The process in which immature B cells from the bone marrow acquire the specialized features of T1 stage B cells in the spleen. T1 stage B cells do not express either CD23 or CD21.	tmpzr1t_l9r_go_relaxed.owl	transitional one stage B-lymphocyte differentiation|transitional one stage B lymphocyte differentiation|T1 stage B cell differentiation|transitional one stage B-cell differentiation|transitional one stage B cell development					Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.								biological_process											owl:Class	
GO:0002332	biolink:NamedThing	transitional stage B cell differentiation	The process in which immature B cells from the bone marrow become mature B cells in the spleen. Transitional stage B cells are subdivided into transitional one (T1) and transitional two (T2) stages and are short-lived and functionally incompetent.	tmpzr1t_l9r_go_relaxed.owl	transitional stage B cell development|transitional stage B-cell differentiation|transitional stage B-lymphocyte differentiation|transitional stage B lymphocyte differentiation					Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.								biological_process											owl:Class	
GO:0060661	biolink:NamedThing	submandibular salivary gland formation	The developmental process pertaining to the initial formation of a submandibular salivary gland. This process begins with a thickening of the epithelium next to the tongue and ends when a bud linked to the oral surface is formed.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-06-01T08:07:16Z					biological_process											owl:Class	
GO:0102945	biolink:NamedThing	soyasapogenol B UDP-glucosyl transferase activity	Catalysis of the reaction: UDP-alpha-D-glucose(2-) + soyasapogenol B <=> UDP(3-) + a soyasapogenol B monoglucoside.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-9037									molecular_function											owl:Class	
GO:0015439	biolink:NamedThing	ABC-type heme transporter activity	Catalysis of the reaction: ATP + H2O + heme(in) = ADP + phosphate + heme(out).	tmpzr1t_l9r_go_relaxed.owl	ATPase-coupled heme transmembrane transporter activity|ATPase-coupled heme transporter activity|heme ABC transporter|ATP-dependent heme transmembrane transporter activity|haem-transporting ATPase activity|heme-transporting ATPase activity|protoheme IX ABC transporter activity				RHEA:19261|EC:7.6.2.5|MetaCyc:3.6.3.41-RXN|Reactome:R-HSA-382560|Reactome:R-HSA-1369065|MetaCyc:TRANS-RXN0-162|Reactome:R-HSA-917979|Reactome:R-HSA-5683355							GO:0103115		molecular_function											owl:Class	
GO:0031022	biolink:NamedThing	nuclear migration along microfilament	The directed movement of the nucleus along microfilaments within the cell, mediated by motor proteins.	tmpzr1t_l9r_go_relaxed.owl	nuclear migration, microfilament-mediated													biological_process											owl:Class	
GO:0015378	biolink:NamedThing	sodium:chloride symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Na+(out) + Cl-(out) = Na+(in) + Cl-(in).	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-426130|Reactome:R-HSA-5623705									molecular_function											owl:Class	
GO:0046985	biolink:NamedThing	positive regulation of hemoglobin biosynthetic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hemoglobin, an oxygen carrying, conjugated protein containing four heme groups and globin.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of hemoglobin formation|positive regulation of hemoglobin anabolism|up-regulation of hemoglobin biosynthetic process|positive regulation of haemoglobin biosynthetic process|up regulation of hemoglobin biosynthetic process|stimulation of hemoglobin biosynthetic process|upregulation of hemoglobin biosynthetic process|positive regulation of hemoglobin synthesis|positive regulation of hemoglobin biosynthesis|activation of hemoglobin biosynthetic process|positive regulation of haemoglobin biosynthesis													biological_process											owl:Class	
GO:0090273	biolink:NamedThing	regulation of somatostatin secretion	Any process that modulates the rate, frequency, extent of the regulated release of somatostatin from secretory granules in the D cells of the pancreas.	tmpzr1t_l9r_go_relaxed.owl								tb	2010-02-05T02:54:14Z					biological_process											owl:Class	
GO:0090276	biolink:NamedThing	regulation of peptide hormone secretion	Any process that modulates the rate, frequency, or extent of the regulated release of a peptide hormone from secretory granules.	tmpzr1t_l9r_go_relaxed.owl								tb	2010-02-05T02:56:39Z					biological_process											owl:Class	
GO:0048367	biolink:NamedThing	shoot system development	The process whose specific outcome is the progression of the shoot system over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl	shoot development											GO:0022621		biological_process											owl:Class	
GO:0047855	biolink:NamedThing	dihydrobunolol dehydrogenase activity	Catalysis of the reaction: dihydrobunolol + NADP(+) = bunolol + H(+) + NADPH.	tmpzr1t_l9r_go_relaxed.owl	(+-)-5-[(tert-butylamino)-2'-hydroxypropoxy]-1,2,3,4-tetrahydro-1-naphthol:NADP+ oxidoreductase activity|bunolol reductase activity				RHEA:15925|MetaCyc:DIHYDROBUNOLOL-DEHYDROGENASE-RXN|KEGG_REACTION:R04623|EC:1.1.1.160									molecular_function											owl:Class	
GO:0033659	biolink:NamedThing	modification by symbiont of host mitochondrion	The process in which an organism effects a change in the structure or function of host cell mitochondria. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0052043	biolink:NamedThing	modification by symbiont of host cellular component	The process in which an organism effects a change in the structure or function of a host cellular component. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0061557	biolink:NamedThing	trigeminal ganglion maturation	A developmental process, independent of morphogenetic (shape) change, that is required for a trigeminal ganglion to attain its fully functional state.	tmpzr1t_l9r_go_relaxed.owl	trigeminal ganglia maturation							dph	2013-07-10T08:58:24Z					biological_process											owl:Class	
GO:0047038	biolink:NamedThing	D-arabinitol 2-dehydrogenase activity	Catalysis of the reaction: D-arabinitol + NAD(+) = D-ribulose + H(+) + NADH.	tmpzr1t_l9r_go_relaxed.owl	D-arabinitol:NAD+ 2-oxidoreductase (D-ribulose-forming)|D-arabinitol 2-dehydrogenase (ribulose-forming) activity				MetaCyc:1.1.1.250-RXN|EC:1.1.1.250|KEGG_REACTION:R07134|RHEA:17389									molecular_function											owl:Class	
GO:0010584	biolink:NamedThing	pollen exine formation	The formation of the pollen exine. The reticulate pollen wall pattern consists of two layers, exine and intine.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0004457	biolink:NamedThing	lactate dehydrogenase activity	Catalysis of the reaction: lactate + NAD+ = H+ + NADH + pyruvate.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0051981	biolink:NamedThing	copper chelate transmembrane transporter activity	Enables the transfer of a copper chelate from one side of a membrane to the other. A copper chelate is a heterocyclic compound having a metal ion attached by coordinate bonds to at least two nonmetal ions.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0030331	biolink:NamedThing	estrogen receptor binding	Binding to an estrogen receptor.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1905051	biolink:NamedThing	regulation of base-excision repair	Any process that modulates the frequency, rate or extent of base-excision repair.	tmpzr1t_l9r_go_relaxed.owl	regulation of BER							ah	2016-03-16T10:52:00Z					biological_process											owl:Class	
GO:0032552	biolink:NamedThing	deoxyribonucleotide binding	Binding to a deoxyribonucleotide, any compound consisting of a deoxyribonucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the deoxyribose moiety.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0043932	biolink:NamedThing	ossification involved in bone remodeling	The formation or growth of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone, involved in response to injury or other physical, physiological or environmental stress stimuli.	tmpzr1t_l9r_go_relaxed.owl	ossification involved in bone remodelling													biological_process											owl:Class	
GO:0047712	biolink:NamedThing	Cypridina-luciferin 2-monooxygenase activity	Catalysis of the reaction: Cypridina luciferin + O2 = oxidized Cypridina luciferin + CO2 + light.	tmpzr1t_l9r_go_relaxed.owl	Cypridina-luciferin:oxygen 2-oxidoreductase (decarboxylating)|luciferase activity|Cypridina-type luciferase activity|luciferase (Cypridina luciferin)|Cypridina luciferase activity				EC:1.13.12.6|RHEA:22760|MetaCyc:CYPRIDINA-LUCIFERIN-2-MONOOXYGENASE-RXN									molecular_function											owl:Class	
GO:0045289	biolink:NamedThing	luciferin monooxygenase activity	Catalysis of the generalized reaction: luciferin + O2 = oxidized luciferin + CO2 + light. There may be additional substrates and reactants involved in the reaction. The reaction results in light emission as luciferin returns to the ground state after enzymatic oxidation.	tmpzr1t_l9r_go_relaxed.owl	luciferase monooxygenase activity|luciferase activity													molecular_function											owl:Class	
GO:0005223	biolink:NamedThing	intracellular cGMP-activated cation channel activity	Enables the transmembrane transfer of a cation by a channel that opens when intracellular cGMP has been bound by the channel complex or one of its constituent parts.	tmpzr1t_l9r_go_relaxed.owl	intracellular cGMP activated cation channel activity													molecular_function											owl:Class	
GO:0030789	biolink:NamedThing	precorrin-3B C17-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + precorrin-3B = S-adenosyl-L-homocysteine + precorrin 4.	tmpzr1t_l9r_go_relaxed.owl	precorrin-3 methyltransferase activity|CobJ|S-adenosyl-L-methionine:precorrin-3B C17-methyltransferase activity|precorrin-3 methylase activity				MetaCyc:2.1.1.131-RXN|EC:2.1.1.131|RHEA:12761									molecular_function											owl:Class	
GO:0032193	biolink:NamedThing	ubiquinone biosynthetic process via 2-polyprenylphenol	The chemical reactions and pathways resulting in the formation of ubiquinone, via the intermediates 2-polyprenylphenol and 2-polyprenyl-6-hydroxyphenol.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0006744	biolink:NamedThing	ubiquinone biosynthetic process	The chemical reactions and pathways resulting in the formation of ubiquinone, a lipid-soluble electron-transporting coenzyme.	tmpzr1t_l9r_go_relaxed.owl	coenzyme Q6 biosynthesis|coenzyme Q8 biosynthesis|ubiquinone synthesis|ubiquinone biosynthesis|coenzyme Q6 biosynthetic process|coenzyme Q8 biosynthetic process|coenzyme Q biosynthetic process|ubiquinone formation|coenzyme Q9 biosynthesis|coenzyme Q9 biosynthetic process|ubiquinone anabolism|coenzyme Q10 biosynthetic process|coenzyme Q biosynthesis|coenzyme Q10 biosynthesis				MetaCyc:UBISYN-PWY									biological_process											owl:Class	
GO:0046885	biolink:NamedThing	regulation of hormone biosynthetic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hormones.	tmpzr1t_l9r_go_relaxed.owl	regulation of hormone anabolism|regulation of hormone biosynthesis|regulation of hormone formation|regulation of hormone synthesis													biological_process											owl:Class	
GO:0045050	biolink:NamedThing	protein insertion into ER membrane by stop-transfer membrane-anchor sequence	A process of protein insertion into the endoplasmic reticulum (ER) membrane in which stop-transfer membrane-anchor sequences become an ER membrane spanning helix.	tmpzr1t_l9r_go_relaxed.owl	protein insertion into ER membrane, stop-transfer membrane-anchor sequence mediated|protein insertion into endoplasmic reticulum membrane by stop-transfer membrane-anchor sequence|protein-ER insertion by stop-transfer membrane-anchor sequence|stop-transfer membrane-anchor sequence mediated protein insertion into ER membrane|protein-endoplasmic reticulum insertion by stop-transfer membrane-anchor sequence													biological_process											owl:Class	
GO:0044869	biolink:NamedThing	negative regulation by host of viral exo-alpha-sialidase activity	The process in which a host organism decreases viral exo-alpha-sialidase activity, the catalysis of the hydrolysis of peptide bonds in a protein.	tmpzr1t_l9r_go_relaxed.owl								jl	2014-09-18T14:13:51Z					biological_process											owl:Class	
GO:0044866	biolink:NamedThing	modulation by host of viral exo-alpha-sialidase activity	The process in which a host organism effects a change in viral exo-alpha-sialidase activity, the catalysis of the hydrolysis of peptide bonds in a protein.	tmpzr1t_l9r_go_relaxed.owl								jl	2014-09-18T11:28:18Z					biological_process											owl:Class	
GO:0043798	biolink:NamedThing	glycerate 2-kinase activity	Catalysis of the reaction: D-glycerate + ATP = 2-phospho-D-glycerate + ADP.	tmpzr1t_l9r_go_relaxed.owl	glycerate kinase|D-glycerate 2-kinase activity				RHEA:27377|EC:2.7.1.165|MetaCyc:GKI-RXN									molecular_function											owl:Class	
GO:0016662	biolink:NamedThing	oxidoreductase activity, acting on other nitrogenous compounds as donors, cytochrome as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which a nitrogenous group, excluding NH and NH2 groups, acts as a hydrogen or electron donor and reduces a cytochrome.	tmpzr1t_l9r_go_relaxed.owl					EC:1.7.2.-									molecular_function											owl:Class	
GO:2000748	biolink:NamedThing	positive regulation of defecation rhythm	Any process that activates or increases the frequency, rate or extent of defecation rhythm.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of defecation cycle|positive regulation of defecation motor program|positive regulation of DMP|positive regulation of defecation behavior							bf	2011-06-15T03:23:13Z					biological_process											owl:Class	
GO:2000746	biolink:NamedThing	regulation of defecation rhythm	Any process that modulates the frequency, rate or extent of defecation rhythm.	tmpzr1t_l9r_go_relaxed.owl	regulation of defecation motor program|regulation of defecation behavior|regulation of DMP|regulation of defecation cycle							bf	2011-06-15T03:23:07Z					biological_process											owl:Class	
GO:0021509	biolink:NamedThing	roof plate formation	The formation of a single row of glia at the dorsal midline of the developing neural tube. This region provides inductive signals for the specification of neuronal cell types and of the specification of neural crest cells. The cells comprising the roof plate are the precursors to radial glial cells.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0060160	biolink:NamedThing	negative regulation of dopamine receptor signaling pathway	Any process that stops, prevents, or reduces the frequency, rate or extent of dopamine receptor protein signaling pathway activity. A dopamine receptor signaling pathway is the series of molecular signals generated as a consequence of a dopamine receptor binding to one of its physiological ligands.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of dopamine receptor signalling pathway													biological_process											owl:Class	
GO:0060159	biolink:NamedThing	regulation of dopamine receptor signaling pathway	Any process that modulates the frequency, rate or extent of a dopamine receptor signaling pathway activity. A dopamine receptor signaling pathway is the series of molecular signals generated as a consequence of a dopamine receptor binding to one of its physiological ligands.	tmpzr1t_l9r_go_relaxed.owl	regulation of dopamine receptor signalling pathway													biological_process											owl:Class	
GO:0034361	biolink:NamedThing	very-low-density lipoprotein particle	A triglyceride-rich lipoprotein particle that is typically composed of APOB100, APOE and APOCs and has a density of about 1.006 g/ml and a diameter of between 20-80 nm. It is found in blood and transports endogenous products (newly synthesized cholesterol and triglycerides) from the liver.	tmpzr1t_l9r_go_relaxed.owl	VLDL complex|very-low-density lipoprotein complex|VLDL particle													cellular_component											owl:Class	
GO:0034385	biolink:NamedThing	triglyceride-rich plasma lipoprotein particle	A plasma lipoprotein particle that has a hydrophobic core enriched in triglycerides surrounded by an amphipathic monolayer of phospholipids, cholesterol and apolipoproteins. Triglyceride-rich lipoprotein particles transport lipids, which are non-covalently associated with the particles, in the blood.	tmpzr1t_l9r_go_relaxed.owl	triacylglycerol-rich lipoprotein particle|triglyceride-rich lipoprotein particle													cellular_component											owl:Class	
GO:0009082	biolink:NamedThing	branched-chain amino acid biosynthetic process	The chemical reactions and pathways resulting in the formation of amino acids containing a branched carbon skeleton, comprising isoleucine, leucine and valine.	tmpzr1t_l9r_go_relaxed.owl	branched chain family amino acid formation|branched chain family amino acid anabolism|branched chain family amino acid biosynthetic process|branched chain family amino acid synthesis|branched chain family amino acid biosynthesis													biological_process											owl:Class	
GO:0006565	biolink:NamedThing	L-serine catabolic process	The chemical reactions and pathways resulting in the breakdown of L-serine, the L-enantiomer of serine, i.e. (2S)-2-amino-3-hydroxypropanoic acid.	tmpzr1t_l9r_go_relaxed.owl	L-serine degradation|L-serine breakdown|L-serine catabolism				MetaCyc:SERDEG-PWY									biological_process											owl:Class	
GO:0006563	biolink:NamedThing	L-serine metabolic process	The chemical reactions and pathways involving L-serine, the L-enantiomer of serine, i.e. (2S)-2-amino-3-hydroxypropanoic acid.	tmpzr1t_l9r_go_relaxed.owl	L-serine metabolism													biological_process											owl:Class	
GO:0044764	biolink:NamedThing	multi-organism cellular process	Any process that is carried out at the cellular level which involves another organism of the same or different species.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-12-11T17:00:50Z					biological_process											owl:Class	
GO:0000469	biolink:NamedThing	cleavage involved in rRNA processing	Any phosphodiester bond hydrolysis involved in the conversion of a primary ribosomal RNA (rRNA) transcript into a mature rRNA molecule.	tmpzr1t_l9r_go_relaxed.owl	cleavage during rRNA processing													biological_process											owl:Class	
GO:0043886	biolink:NamedThing	structural constituent of carboxysome	The action of a molecule that contributes to the structural integrity of a carboxysome, an organelle found in all cyanobacteria and some chemoautotrophs, consisting of a proteinaceous coat and enzymes for the fixation of CO(2).	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/19743												molecular_function											owl:Class	
GO:1904120	biolink:NamedThing	positive regulation of otic vesicle morphogenesis	Any process that activates or increases the frequency, rate or extent of otic vesicle morphogenesis.	tmpzr1t_l9r_go_relaxed.owl	up regulation of otic vesicle morphogenesis|activation of otic vesicle morphogenesis|up-regulation of otic vesicle morphogenesis|upregulation of otic vesicle morphogenesis							pga	2015-04-07T14:01:08Z					biological_process											owl:Class	
GO:1903295	biolink:NamedThing	negative regulation of glutamate secretion, neurotransmission	Any process that stops, prevents or reduces the frequency, rate or extent of glutamate secretion, neurotransmission.	tmpzr1t_l9r_go_relaxed.owl	down regulation of glutamate secretion, neurotransmission|inhibition of glutamate secretion, neurotransmission|downregulation of glutamate secretion, neurotransmission|down-regulation of glutamate secretion, neurotransmission					An example of this is Rab3gap1 in mouse (Q80UJ7) in PMID:16782817 inferred from mutant phenotype		pad	2014-08-13T13:54:23Z					biological_process											owl:Class	
GO:0010739	biolink:NamedThing	positive regulation of protein kinase A signaling	Any process that increases the rate, frequency, or extent of protein kinase A signaling. PKA signaling is the series of reactions, mediated by the intracellular serine/threonine kinase protein kinase A, which occurs as a result of a single trigger reaction or compound.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of protein kinase A signalling cascade|positive regulation of protein kinase A signaling cascade|positive regulation of PKA signaling cascade													biological_process											owl:Class	
GO:0045590	biolink:NamedThing	negative regulation of regulatory T cell differentiation	Any process that stops, prevents, or reduces the rate of differentiation of regulatory T cells.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of regulatory T cell differentiation|negative regulation of regulatory T lymphocyte differentiation|negative regulation of regulatory T-lymphocyte differentiation|down regulation of regulatory T cell differentiation|downregulation of regulatory T cell differentiation|negative regulation of regulatory T cell development|negative regulation of regulatory T-cell differentiation|negative regulation of suppressor T cell differentiation|inhibition of regulatory T cell differentiation|negative regulation of suppressor T-cell differentiation					Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.								biological_process											owl:Class	
GO:0050841	biolink:NamedThing	peptidyl-N6,N6,N6-trimethyl-lysine hydroxylation to peptidyl-N6,N6,N6-trimethyl-5-hydroxy-L-lysine	The hydroxylation of peptidyl-N6,N6,N6-trimethyl-L-lysine to form peptidyl-N6,N6,N6-trimethyl-5-hydroxy-L-lysine.	tmpzr1t_l9r_go_relaxed.owl	peptidyl-trimethyl-lysine hydroxylase activity|peptidyl trimethyl lysine hydroxylase activity				RESID:AA0359									biological_process											owl:Class	
GO:0006754	biolink:NamedThing	ATP biosynthetic process	The chemical reactions and pathways resulting in the formation of ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.	tmpzr1t_l9r_go_relaxed.owl	ATP biosynthesis|ATP synthesis|ATP anabolism|ATP formation|ATP regeneration											GO:0006758|GO:0006759		biological_process											owl:Class	
GO:0097645	biolink:NamedThing	amylin binding	Binding to amylin.	tmpzr1t_l9r_go_relaxed.owl								pr	2014-09-08T20:53:03Z					molecular_function											owl:Class	
GO:0097644	biolink:NamedThing	calcitonin family binding	Binding to a member of the calcitonin family (e.g. adrenomedullin, adrenomedullin 2 (intermedin), amylin, calcitonin and calcitonin gene-related peptides (CGRPs)).	tmpzr1t_l9r_go_relaxed.owl								pr	2014-09-08T20:50:52Z					molecular_function											owl:Class	
GO:0010608	biolink:NamedThing	posttranscriptional regulation of gene expression	Any process that modulates the frequency, rate or extent of gene expression after the production of an RNA transcript.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0010351	biolink:NamedThing	lithium ion transport	The directed movement of lithium ion into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	lithium transport													biological_process											owl:Class	
GO:1990034	biolink:NamedThing	calcium ion export across plasma membrane	The directed movement of calcium ions from inside of a cell, across the plasma membrane and into the extracellular region.	tmpzr1t_l9r_go_relaxed.owl	calcium ion export from cell|calcium ion efflux from cell							mah	2013-02-07T13:01:29Z					biological_process											owl:Class	
GO:0000837	biolink:NamedThing	Doa10p ubiquitin ligase complex	A multiprotein complex that recognizes and ubiquitinates membrane proteins with misfolded cytosolic domains during ER-associated protein degradation (ERAD). In S. cerevisiae, this complex contains the ubiquitin ligase Ssm4p/Doa10p.	tmpzr1t_l9r_go_relaxed.owl	Ssm4p ubiquitin ligase complex													cellular_component											owl:Class	
GO:0000835	biolink:NamedThing	ER ubiquitin ligase complex	A ubiquitin ligase complex found in the ER.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0001799	biolink:NamedThing	regulation of type IIb hypersensitivity	Any process that modulates the frequency, rate, or extent of type IIb hypersensitivity, a type of inflammatory response.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1904004	biolink:NamedThing	positive regulation of sebum secreting cell proliferation	Any process that activates or increases the frequency, rate or extent of sebum secreting cell proliferation.	tmpzr1t_l9r_go_relaxed.owl	up regulation of sebum secreting cell proliferation|upregulation of sebocyte proliferation|activation of sebum secreting cell proliferation|activation of sebocyte proliferation|up-regulation of sebum secreting cell proliferation|up-regulation of sebocyte proliferation|upregulation of sebum secreting cell proliferation|positive regulation of sebocyte proliferation|up regulation of sebocyte proliferation							hjd	2015-03-06T16:19:56Z					biological_process											owl:Class	
GO:0080082	biolink:NamedThing	esculin beta-glucosidase activity	Catalysis of the hydrolysis of glucosidic link in esculin.	tmpzr1t_l9r_go_relaxed.owl								dhl	2009-04-14T04:09:42Z					molecular_function											owl:Class	
GO:0060313	biolink:NamedThing	negative regulation of blood vessel remodeling	Any process that decreases the rate, frequency or extent of blood vessel remodeling, the reorganization or renovation of existing blood vessels.	tmpzr1t_l9r_go_relaxed.owl	inhibition of blood vessel remodeling|down-regulation of blood vessel remodeling													biological_process											owl:Class	
GO:0071393	biolink:NamedThing	cellular response to progesterone stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a progesterone stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-12-11T04:11:13Z					biological_process											owl:Class	
GO:0001525	biolink:NamedThing	angiogenesis	Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels.	tmpzr1t_l9r_go_relaxed.owl	blood vessel formation from pre-existing blood vessels				Wikipedia:Angiogenesis									biological_process											owl:Class	
GO:0046567	biolink:NamedThing	aphidicolan-16 beta-ol synthase activity	Catalysis of the reaction: 9-alpha-copalyl diphosphate + H2O = aphidicolan-16-beta-ol + diphosphate.	tmpzr1t_l9r_go_relaxed.owl	9-alpha-copalyl-diphosphate diphosphate-lyase (aphidicolan-16-beta-ol-forming)				KEGG_REACTION:R06313|MetaCyc:RXN-10631|EC:4.2.3.42|RHEA:26213									molecular_function											owl:Class	
GO:0060189	biolink:NamedThing	positive regulation of protein desumoylation	Any process that increases the frequency, rate or extent of protein desumoylation. Protein desumoylation is the process in which a SUMO protein (small ubiquitin-related modifier) is cleaved from its target protein.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0060188	biolink:NamedThing	regulation of protein desumoylation	Any process that modulates the frequency, rate or extent of protein desumoylation. Protein desumoylation is the process in which a SUMO protein (small ubiquitin-related modifier) is cleaved from its target protein.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0045863	biolink:NamedThing	negative regulation of pteridine metabolic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving pteridine.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of pteridine metabolic process|inhibition of pteridine metabolic process|negative regulation of pteridine metabolism|downregulation of pteridine metabolic process|down regulation of pteridine metabolic process													biological_process											owl:Class	
GO:0017020	biolink:NamedThing	myosin phosphatase regulator activity	Binds to and modulates of the activity of myosin phosphatase.	tmpzr1t_l9r_go_relaxed.owl	myosin phosphatase, intrinsic regulator activity													molecular_function											owl:Class	
GO:0047609	biolink:NamedThing	acetylputrescine deacetylase activity	Catalysis of the reaction: N-acetylputrescine + H(2)O = acetate + putrescine.	tmpzr1t_l9r_go_relaxed.owl	N-acetylputrescine acetylhydrolase activity				EC:3.5.1.62|MetaCyc:ACETYLPUTRESCINE-DEACETYLASE-RXN|RHEA:23412|KEGG_REACTION:R01156									molecular_function											owl:Class	
GO:0003302	biolink:NamedThing	transforming growth factor beta receptor signaling pathway involved in heart jogging	A series of molecular signals initiated by the binding of an extracellular ligand to a transforming growth factor beta receptor on the surface of a target cell, which contributes to the process of heart jogging.	tmpzr1t_l9r_go_relaxed.owl	transforming growth factor beta receptor signalling pathway involved in heart jogging							dph	2009-10-22T10:51:58Z					biological_process											owl:Class	
GO:1905313	biolink:NamedThing	transforming growth factor beta receptor signaling pathway involved in heart development	Any transforming growth factor beta receptor signaling pathway that is involved in heart development.	tmpzr1t_l9r_go_relaxed.owl	TGF-beta receptor signaling pathway involved in cardiac development|TGF-beta receptor signalling pathway involved in cardiac development|transforming growth factor beta receptor signaling pathway involved in dorsal vessel development|TGF-beta receptor signalling pathway involved in dorsal vessel development|TGFbeta receptor signaling pathway involved in dorsal vessel development|TGFbeta receptor signaling pathway involved in cardiac development|TGF-beta receptor signaling pathway involved in dorsal vessel development|transforming growth factor beta receptor signalling pathway involved in dorsal vessel development|TGFbeta receptor signalling pathway involved in dorsal vessel development|TGFbeta receptor signaling pathway involved in heart development|TGF-beta receptor signaling pathway involved in heart development|TGFbeta receptor signalling pathway involved in heart development|TGFbeta receptor signalling pathway involved in cardiac development|transforming growth factor beta receptor signalling pathway involved in cardiac development|TGF-beta receptor signalling pathway involved in heart development|transforming growth factor beta receptor signalling pathway involved in heart development|transforming growth factor beta receptor signaling pathway involved in cardiac development							rl	2016-07-11T17:45:38Z					biological_process											owl:Class	
GO:0035523	biolink:NamedThing	protein K29-linked deubiquitination	A protein deubiquitination process in which a K29-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 29 of the ubiquitin monomers, is removed from a protein.	tmpzr1t_l9r_go_relaxed.owl	protein K29-linked deubiquitinylation|protein K29-linked deubiquitylation							bf	2010-05-04T04:33:27Z					biological_process											owl:Class	
GO:1903808	biolink:NamedThing	L-tyrosine import across plasma membrane	The directed movement of L-tyrosine from outside of a cell, across the plasma membrane and into the cytosol.	tmpzr1t_l9r_go_relaxed.owl	L-tyrosine uptake|L-tyrosine import into cell|L-tyrosine import							bf	2012-05-11T10:46:21Z			GO:0036232		biological_process											owl:Class	
GO:0016476	biolink:NamedThing	regulation of embryonic cell shape	Any process that modulates the surface configuration of an embryonic cell.	tmpzr1t_l9r_go_relaxed.owl	shape changes of embryonic cells													biological_process											owl:Class	
GO:0061097	biolink:NamedThing	regulation of protein tyrosine kinase activity	Any process that modulates the rate, frequency, or extent of protein tyrosine kinase activity.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-04-26T02:34:53Z					biological_process											owl:Class	
GO:0070741	biolink:NamedThing	response to interleukin-6	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-6 stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to IL-6							mah	2009-06-19T03:39:12Z					biological_process											owl:Class	
GO:1904960	biolink:NamedThing	positive regulation of cytochrome-c oxidase activity	Any process that activates or increases the frequency, rate or extent of cytochrome-c oxidase activity.	tmpzr1t_l9r_go_relaxed.owl	up regulation of ba3-type cytochrome c oxidase|positive regulation of cbb3-type cytochrome c oxidase|up regulation of cytochrome aa3 activity|upregulation of cytochrome aa3 activity|activation of warburg's respiratory enzyme activity|up-regulation of warburg's respiratory enzyme activity|activation of indophenolase|up regulation of indophenol oxidase|activation of ferrocytochrome-c:oxygen oxidoreductase|upregulation of indophenol oxidase|upregulation of cytochrome c oxidase activity|activation of caa3-type cytochrome c oxidase|positive regulation of cytochrome a3 activity|positive regulation of cytochrome aa3 activity|up-regulation of caa3-type cytochrome c oxidase|positive regulation of NADH cytochrome c oxidase|up regulation of ferrocytochrome-c:oxygen oxidoreductase|upregulation of ba3-type cytochrome c oxidase|up-regulation of cytochrome aa3 activity|up regulation of cytochrome-c oxidase activity|up regulation of aa3-type cytochrome c oxidase|upregulation of aa3-type cytochrome c oxidase|up regulation of NADH cytochrome c oxidase|up-regulation of NADH cytochrome c oxidase|positive regulation of indophenol oxidase|upregulation of indophenolase|upregulation of complex IV (mitochondrial electron transport) activity|positive regulation of aa3-type cytochrome c oxidase|activation of indophenol oxidase|up-regulation of cytochrome c oxidase activity|upregulation of cytochrome-c oxidase activity|activation of cytochrome a3 activity|up-regulation of cbb3-type cytochrome c oxidase|up-regulation of ferrocytochrome-c:oxygen oxidoreductase|positive regulation of ferrocytochrome-c:oxygen oxidoreductase|up-regulation of indophenol oxidase|upregulation of ferrocytochrome-c:oxygen oxidoreductase|up regulation of cbb3-type cytochrome c oxidase|up regulation of indophenolase|positive regulation of cytochrome oxidase activity|positive regulation of warburg's respiratory enzyme activity|activation of cbb3-type cytochrome c oxidase|upregulation of cbb3-type cytochrome c oxidase|up-regulation of ferrocytochrome c oxidase|up regulation of caa3-type cytochrome c oxidase|up regulation of complex IV (mitochondrial electron transport) activity|activation of cytochrome-c oxidase activity|up-regulation of aa3-type cytochrome c oxidase|activation of cytochrome oxidase activity|upregulation of warburg's respiratory enzyme activity|positive regulation of indophenolase|upregulation of ferrocytochrome c oxidase|up regulation of cytochrome c oxidase activity|up-regulation of cytochrome oxidase activity|activation of complex IV (mitochondrial electron transport) activity|up-regulation of cytochrome-c oxidase activity|activation of NADH cytochrome c oxidase|positive regulation of caa3-type cytochrome c oxidase|up-regulation of cytochrome a3 activity|up-regulation of complex IV (mitochondrial electron transport) activity|upregulation of caa3-type cytochrome c oxidase|positive regulation of cytochrome c oxidase activity|upregulation of cytochrome oxidase activity|up regulation of warburg's respiratory enzyme activity|up-regulation of ba3-type cytochrome c oxidase|positive regulation of ferrocytochrome c oxidase|up regulation of ferrocytochrome c oxidase|upregulation of cytochrome a3 activity|positive regulation of ba3-type cytochrome c oxidase|activation of ferrocytochrome c oxidase|up regulation of cytochrome oxidase activity|up-regulation of indophenolase|activation of cytochrome c oxidase activity|activation of ba3-type cytochrome c oxidase|upregulation of NADH cytochrome c oxidase|positive regulation of complex IV (mitochondrial electron transport) activity|up regulation of cytochrome a3 activity|activation of aa3-type cytochrome c oxidase|activation of cytochrome aa3 activity							tb	2016-02-09T22:18:43Z					biological_process											owl:Class	
GO:2000323	biolink:NamedThing	negative regulation of glucocorticoid receptor signaling pathway	Any process that stops, prevents or reduces the frequency, rate or extent of glucocorticoid receptor signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of glucocorticoid receptor signalling pathway							vk	2011-01-18T04:38:43Z					biological_process											owl:Class	
GO:1900522	biolink:NamedThing	negative regulation of response to amylopectin	Any process that stops, prevents or reduces the frequency, rate or extent of response to amylopectin.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of response to amylopectin|downregulation of response to amylopectin|inhibition of response to amylopectin|down regulation of response to amylopectin							tt	2012-05-02T04:14:01Z					biological_process											owl:Class	
GO:1900539	biolink:NamedThing	fumonisin metabolic process	The chemical reactions and pathways involving fumonisin.	tmpzr1t_l9r_go_relaxed.owl	fumonisin metabolism							tb	2012-05-11T12:53:29Z					biological_process											owl:Class	
GO:0050317	biolink:NamedThing	tagatose kinase activity	Catalysis of the reaction: D-tagatose + ATP = D-tagatose 6-phosphate + ADP + 2 H(+).	tmpzr1t_l9r_go_relaxed.owl	ATP:D-tagatose 6-phosphotransferase activity|tagatose 6-phosphate kinase (phosphorylating)|D-tagatose 6-phosphate kinase activity				RHEA:15513|KEGG_REACTION:R02927|EC:2.7.1.101|MetaCyc:TAGATOSE-KINASE-RXN									molecular_function											owl:Class	
GO:0048936	biolink:NamedThing	peripheral nervous system neuron axonogenesis	Generation of a long process from a neuron whose cell body resides in the peripheral nervous system. The axon carries action potential from the cell body towards target cells.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0090424	biolink:NamedThing	phytochelatin-metal-sulfur complex formation	A phytochelatin metabolic process in which a metal and exogenous sulfur are incorporated with phytochelatin to form a complex.	tmpzr1t_l9r_go_relaxed.owl	high molecular weight phytochelatin complex formation|HWM phytochelatin complex formation							tb	2012-04-20T03:46:45Z					biological_process											owl:Class	
GO:0120328	biolink:NamedThing	ATP-dependent DNA (cytosine-5-)-methyltransferase activity	Catalytic activity that acts to transfer a methyl group to a DNA molecule, driven by ATP hydrolysis.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/21872						krc	2021-08-16T21:00:16Z					molecular_function											owl:Class	
GO:0072712	biolink:NamedThing	response to thiabendazole	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a thiabendazole stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to TBZ							mah	2012-04-11T04:23:56Z					biological_process											owl:Class	
GO:0009772	biolink:NamedThing	photosynthetic electron transport in photosystem II	A photosynthetic electron transport chain in which electrons move from the primary electron acceptor (Quinone, Q) through a chain of electron transport molecules in the thylakoid membrane until they reach the ultimate electron acceptor of Photosystem II, which is plastocyanin (PC). The electron is then passed to the P700 chlorophyll a molecules of the reaction centre of photosystem I.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0009767	biolink:NamedThing	photosynthetic electron transport chain	A process, occurring as part of photosynthesis, in which light provides the energy for a series of electron carriers to operate together to transfer electrons and generate a transmembrane electrochemical gradient.	tmpzr1t_l9r_go_relaxed.owl	photosynthetic electron transport in plastocyanin|electron carrier, chlorophyll electron transport system|photosynthetic electron transport in cytochrome b6/f|photosynthetic electron transport in plastoquinone											GO:0009775|GO:0009774|GO:0009776		biological_process											owl:Class	
GO:1902003	biolink:NamedThing	regulation of amyloid-beta formation	Any process that modulates the frequency, rate or extent of amyloid-beta formation.	tmpzr1t_l9r_go_relaxed.owl	regulation of beta-amyloid formation							dph	2013-03-21T19:59:26Z					biological_process											owl:Class	
GO:0070319	biolink:NamedThing	Golgi to plasma membrane transport vesicle	A transport vesicle that mediates transport from the Golgi to the plasma membrane, and fuses with the plasma membrane to release various cargo molecules, such as proteins or hormones, by exocytosis.	tmpzr1t_l9r_go_relaxed.owl	Golgi-plasma membrane transport vesicle|Golgi to plasma membrane constitutive secretory pathway transport vesicle													cellular_component											owl:Class	
GO:0034103	biolink:NamedThing	regulation of tissue remodeling	Any process that modulates the frequency, rate, or extent of tissue remodeling.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0003164	biolink:NamedThing	His-Purkinje system development	The process whose specific outcome is the progression of the His-Purkinje system over time, from its formation to the mature structure. The His-Purkinje system receives signals from the AV node and is composed of the fibers that regulate cardiac muscle contraction in the ventricles.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-10-01T02:07:12Z					biological_process											owl:Class	
GO:0003229	biolink:NamedThing	ventricular cardiac muscle tissue development	The process whose specific outcome is the progression of ventricular cardiac muscle over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl	ventricular myocardium development							dph	2009-10-13T10:56:01Z					biological_process											owl:Class	
GO:0016494	biolink:NamedThing	C-X-C chemokine receptor activity	Combining with a C-X-C chemokine and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. A C-X-C chemokine has a single amino acid between the first two cysteines of the characteristic four cysteine motif.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0035481	biolink:NamedThing	positive regulation of Notch signaling pathway involved in heart induction	Any process that activates or increases the frequency, rate or extent of the series of molecular signals initiated by binding of an extracellular ligand to a Notch receptor on the surface of the target cell that contributes to heart induction.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of Notch signalling pathway involved in heart induction							bf	2010-04-23T10:41:04Z					biological_process											owl:Class	
GO:1905241	biolink:NamedThing	positive regulation of canonical Wnt signaling pathway involved in osteoblast differentiation	Any process that activates or increases the frequency, rate or extent of canonical Wnt signaling pathway involved in osteoblast differentiation.	tmpzr1t_l9r_go_relaxed.owl	activation of canonical Wnt-activated signaling pathway involved in osteoblast differentiation|up regulation of canonical Wnt receptor signalling pathway involved in osteoblast differentiation|up regulation of canonical Wnt receptor signaling pathway involved in osteoblast differentiation|upregulation of canonical Wnt receptor signalling pathway involved in osteoblast differentiation|activation of canonical Wnt signaling pathway involved in osteoblast differentiation|up-regulation of canonical Wnt signaling pathway involved in osteoblast differentiation|activation of canonical Wnt receptor signaling pathway involved in osteoblast differentiation|up regulation of canonical Wnt signaling pathway involved in osteoblast differentiation|activation of canonical Wnt receptor signalling pathway involved in osteoblast differentiation|positive regulation of canonical Wnt receptor signalling pathway involved in osteoblast differentiation|up-regulation of canonical Wnt receptor signaling pathway involved in osteoblast differentiation|upregulation of canonical Wnt-activated signaling pathway involved in osteoblast differentiation|up regulation of canonical Wnt-activated signaling pathway involved in osteoblast differentiation|upregulation of canonical Wnt signaling pathway involved in osteoblast differentiation|positive regulation of canonical Wnt receptor signaling pathway involved in osteoblast differentiation|up-regulation of canonical Wnt receptor signalling pathway involved in osteoblast differentiation|positive regulation of canonical Wnt-activated signaling pathway involved in osteoblast differentiation|upregulation of canonical Wnt receptor signaling pathway involved in osteoblast differentiation|up-regulation of canonical Wnt-activated signaling pathway involved in osteoblast differentiation							rph	2016-06-08T10:26:49Z					biological_process											owl:Class	
GO:0044863	biolink:NamedThing	modulation by virus of host cell division	Any process where an infecting virus modulates the frequency, rate or extent of the physical partitioning and separation of its host's cell into daughter cells.	tmpzr1t_l9r_go_relaxed.owl	regulation by virus of host cell division							jl	2014-08-05T16:30:03Z					biological_process											owl:Class	
GO:0010292	biolink:NamedThing	GTP:GDP antiporter activity	Catalysis of the reaction: GTP(out) + GDP(in) = GTP(in) + GDP(out).	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0048472	biolink:NamedThing	threonine-phosphate decarboxylase activity	Catalysis of the reaction: O-phospho-L-threonine + H(+) = (R)-1-aminopropan-2-yl phosphate + CO(2).	tmpzr1t_l9r_go_relaxed.owl	L-threonine-O-3-phosphate decarboxylase activity|L-threonine O-3-phosphate carboxy-lyase activity|CobD|L-threonine O-3-phosphate carboxy-lyase [(R)-1-aminopropan-2-yl-phosphate-forming]				KEGG_REACTION:R06530|EC:4.1.1.81|MetaCyc:4.1.1.81-RXN|RHEA:11492									molecular_function											owl:Class	
GO:0070044	biolink:NamedThing	synaptobrevin 2-SNAP-25-syntaxin-1a complex	A SNARE complex that contains synaptobrevin 2 (VAMP2), SNAP-25, and syntaxin 1a (or orthologs thereof).	tmpzr1t_l9r_go_relaxed.owl	Snap25-Stx1a-Vamp2 complex|SNARE complex (Stx1a, SNAP25, VAMP)|SNARE complex (Snap25, Stx1a, Vamp2)|Stx1a-SNAP25-VAMP complex													cellular_component											owl:Class	
GO:0004177	biolink:NamedThing	aminopeptidase activity	Catalysis of the hydrolysis of a single N-terminal amino acid residue from a polypeptide chain.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/19681			Reactome:R-HSA-983162|MetaCyc:RXN0-5052|Reactome:R-HSA-1236954|Reactome:R-HSA-8851929|EC:3.4.11.-|Reactome:R-HSA-2534096									molecular_function											owl:Class	
GO:0062196	biolink:NamedThing	regulation of lysosome size	Any process that modulates the size of a lysosome.	tmpzr1t_l9r_go_relaxed.owl								dph	2019-12-09T21:06:44Z					biological_process											owl:Class	
GO:0110119	biolink:NamedThing	positive regulation of very-low-density lipoprotein particle clearance	Any process that increases the frequency, rate or extent of very-low-density lipoprotein particle clearance.	tmpzr1t_l9r_go_relaxed.owl								kmv	2018-07-27T14:13:47Z					biological_process											owl:Class	
GO:0061200	biolink:NamedThing	clathrin-sculpted gamma-aminobutyric acid transport vesicle	A clathrin-sculpted lipid bilayer membrane-enclosed vesicle after clathrin release and containing gamma-aminobutyric acid transport vesicle.	tmpzr1t_l9r_go_relaxed.owl	clathrin sculpted GABA transport vesicle|clathrin sculpted gamma-aminobutyric acid transport vesicle							dph	2010-07-29T10:40:43Z					cellular_component											owl:Class	
GO:0060198	biolink:NamedThing	clathrin-sculpted vesicle	A clathrin-sculpted lipid bilayer membrane-enclosed vesicle after clathrin release.	tmpzr1t_l9r_go_relaxed.owl	clathrin sculpted vesicle													cellular_component											owl:Class	
GO:0030279	biolink:NamedThing	negative regulation of ossification	Any process that stops, prevents, or reduces the frequency, rate or extent of ossification, the formation of bone or of a bony substance or the conversion of fibrous tissue or of cartilage into bone or a bony substance.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of ossification|inhibition of ossification|downregulation of ossification|negative regulation of bone formation|down regulation of ossification|negative regulation of bone biosynthesis													biological_process											owl:Class	
GO:0030149	biolink:NamedThing	sphingolipid catabolic process	The chemical reactions and pathways resulting in the breakdown of sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid).	tmpzr1t_l9r_go_relaxed.owl	sphingolipid breakdown|sphingolipid catabolism|sphingolipid degradation													biological_process											owl:Class	
GO:0048443	biolink:NamedThing	stamen development	The process whose specific outcome is the progression of the stamen over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl												GO:0048425		biological_process											owl:Class	
GO:0048437	biolink:NamedThing	floral organ development	The process whose specific outcome is the progression of the floral organ over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl												GO:0048433		biological_process											owl:Class	
GO:0002369	biolink:NamedThing	T cell cytokine production	Any process that contributes to cytokine production by a T cell.	tmpzr1t_l9r_go_relaxed.owl	T-lymphocyte cytokine production|T-cell cytokine production|T lymphocyte cytokine production					Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.								biological_process											owl:Class	
GO:0008049	biolink:NamedThing	male courtship behavior	The behavior of a male, for the purpose of attracting a sexual partner. An example of this process is found in Drosophila melanogaster.	tmpzr1t_l9r_go_relaxed.owl	male courtship behaviour											GO:0016542		biological_process											owl:Class	
GO:0015055	biolink:NamedThing	secretin receptor activity	Combining with secretin to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0002646	biolink:NamedThing	regulation of central tolerance induction	Any process that modulates the frequency, rate, or extent of central tolerance induction.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0062009	biolink:NamedThing	secondary palate development	The biological process whose specific outcome is the progression of the secondary palate from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure. The secondary palate is the part of the palate formed from the fusion of the two palatine shelves, extensions of the maxillary prominences.	tmpzr1t_l9r_go_relaxed.owl								dph	2018-02-26T22:55:20Z					biological_process											owl:Class	
GO:0060021	biolink:NamedThing	roof of mouth development	The biological process whose specific outcome is the progression of the roof of the mouth from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure. The roof of the mouth is the partition that separates the nasal and oral cavities.	tmpzr1t_l9r_go_relaxed.owl	palatum development													biological_process											owl:Class	
GO:0090442	biolink:NamedThing	trehalose catabolism in response to heat stress	The chemical reactions and pathways resulting in the degradation of trehalose that occur as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.	tmpzr1t_l9r_go_relaxed.owl	trehalose catabolic process in response to heat stress							tb	2012-08-23T13:53:07Z					biological_process											owl:Class	
GO:0008334	biolink:NamedThing	histone mRNA metabolic process	The chemical reactions and pathways involving an mRNA encoding a histone.	tmpzr1t_l9r_go_relaxed.owl	stem-loop-containing histone mRNA 3'-end processing|histone mRNA metabolism					In higher Eukaryotes, histone mRNAs (stem-loop containing) are non-polyadenylated and thus have a different form of 3'-end regulation to other mRNAs. In lower Eukaryotes, the 3'-ends of histone mRNAs are polyadenylated.								biological_process											owl:Class	
GO:0010743	biolink:NamedThing	regulation of macrophage derived foam cell differentiation	Any process that modulates the rate, frequency or extent of macrophage derived foam cell differentiation. Macrophage derived foam cell differentiation is the process in which a macrophage acquires the specialized features of a foam cell. A foam cell is a type of cell containing lipids in small vacuoles and typically seen in atherosclerotic lesions, as well as other conditions.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0050656	biolink:NamedThing	3'-phosphoadenosine 5'-phosphosulfate binding	Binding to 3'-phosphoadenosine 5'-phosphosulfate (PAPS), a naturally occurring mixed anhydride. It is an intermediate in the formation of a variety of sulfo compounds in biological systems.	tmpzr1t_l9r_go_relaxed.owl	PAPS binding|3'-phosphoadenosine 5'-phosphosulphate binding|adenosine 3'-phosphate 5'-phosphosulfate binding|phosphoadenosine phosphosulfate binding|3'-phosphoadenylyl-sulfate binding													molecular_function											owl:Class	
GO:0031278	biolink:NamedThing	alpha-1,2-galactosyltransferase activity	Catalysis of the transfer of a galactose residue from a donor molecule, such as GDP-galactose or UDP-galactose, to an oligosaccharide, forming an alpha-1,2-linkage.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0061834	biolink:NamedThing	actin filament branch point	The part of an actin filament where the structure forks.	tmpzr1t_l9r_go_relaxed.owl	microfilament branch point													cellular_component											owl:Class	
GO:0000495	biolink:NamedThing	box H/ACA RNA 3'-end processing	Any process involved in forming the mature 3' end of a box H/ACA RNA molecule.	tmpzr1t_l9r_go_relaxed.owl	box H/ACA RNA 3' end processing|box H/ACA sRNA 3'-end processing|box H/ACA snoRNA 3'-end processing	https://github.com/geneontology/go-ontology/issues/20416												biological_process											owl:Class	
GO:0002869	biolink:NamedThing	positive regulation of B cell deletion	Any process that activates or increases the frequency, rate, or extent of B cell deletion.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of B lymphocyte deletion|upregulation of B cell deletion|up regulation of B cell deletion|up-regulation of B cell deletion|activation of B cell deletion|stimulation of B cell deletion|positive regulation of B-lymphocyte deletion|positive regulation of B-cell deletion													biological_process											owl:Class	
GO:0071202	biolink:NamedThing	Kv4.3-DPP10 channel complex	A voltage-gated potassium channel complex that contains the peptidase-related protein DPP10 associated with the channel via interaction with the Kv alpha subunit 4.3.	tmpzr1t_l9r_go_relaxed.owl	Kv4.3-DPPY channel complex				CORUM:598			mah	2009-11-23T05:21:37Z					cellular_component											owl:Class	
GO:0043727	biolink:NamedThing	5-amino-4-imidazole carboxylate lyase activity	Catalysis of the reaction: 5-aminoimidazole + CO2 = 5-amino-4-imidazole carboxylate.	tmpzr1t_l9r_go_relaxed.owl					EC:4.1.1.21									molecular_function											owl:Class	
GO:0007619	biolink:NamedThing	courtship behavior	The behavior of an organism for the purpose of attracting sexual partners.	tmpzr1t_l9r_go_relaxed.owl	courtship behaviour													biological_process											owl:Class	
GO:0002340	biolink:NamedThing	central B cell selection	Any B cell selection process that occurs in the bone marrow.	tmpzr1t_l9r_go_relaxed.owl	central B-cell selection|central B-lymphocyte selection|central B lymphocyte selection													biological_process											owl:Class	
GO:0048809	biolink:NamedThing	analia morphogenesis	The process in which the anatomical structures of analia are generated and organized. The analia is the posterior-most vertral appendage that develops from the genital disc. An example of this process is analia morphogenesis in Drosophila melanogaster.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1905913	biolink:NamedThing	negative regulation of calcium ion export across plasma membrane	Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion export across the plasma membrane.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of calcium ion export from cell|down regulation of calcium ion efflux from cell|negative regulation of calcium ion efflux from cell|downregulation of calcium ion export from cell|inhibition of calcium ion efflux from cell|inhibition of calcium ion export from cell|down-regulation of calcium ion efflux from cell|down regulation of calcium ion export from cell|downregulation of calcium ion efflux from cell|negative regulation of calcium ion export from cell							rph	2017-02-07T13:20:48Z					biological_process											owl:Class	
GO:1905912	biolink:NamedThing	regulation of calcium ion export across plasma membrane	Any process that modulates the frequency, rate or extent of calcium ion export across the plasma membrane.	tmpzr1t_l9r_go_relaxed.owl	regulation of calcium ion export from cell|regulation of calcium ion efflux from cell							rph	2017-02-07T13:20:39Z					biological_process											owl:Class	
GO:0106025	biolink:NamedThing	positive regulation of pupariation	Any process that activates or increases the frequency, rate or extent of onset of pupariation.	tmpzr1t_l9r_go_relaxed.owl								hjd	2017-05-24T19:37:50Z					biological_process											owl:Class	
GO:0003057	biolink:NamedThing	regulation of the force of heart contraction by chemical signal	The regulation of the force of heart muscle contraction mediated by chemical signaling, hormonal, autocrine or paracrine.	tmpzr1t_l9r_go_relaxed.owl	chemical cardiac inotropy|regulation of the force of heart muscle contraction by chemical signal													biological_process											owl:Class	
GO:0047173	biolink:NamedThing	phosphatidylcholine-retinol O-acyltransferase activity	Catalysis of the reaction: retinol-[cellular-retinol-binding-protein] + phosphatidylcholine = retinyl-ester-[cellular-retinol-binding-protein] + 2-acylglycerophosphocholine.	tmpzr1t_l9r_go_relaxed.owl	lecithin--retinol acyltransferase activity|phosphatidylcholine:retinol-[cellular-retinol-binding-protein] O-acyltransferase activity|phosphatidylcholine:retinol-(cellular-retinol-binding-protein) O-acyltransferase activity				MetaCyc:2.3.1.135-RXN|Reactome:R-HSA-975608|RHEA:17469|EC:2.3.1.135									molecular_function											owl:Class	
GO:1903861	biolink:NamedThing	positive regulation of dendrite extension	Any process that activates or increases the frequency, rate or extent of dendrite extension.	tmpzr1t_l9r_go_relaxed.owl	activation of dendrite extension|up regulation of dendrite extension|upregulation of dendrite extension|up-regulation of dendrite extension					An example of this is Mul1 in mouse (UniProt ID Q8VCM5) in PMID:24898855 inferred from mutant phenotype.		pad	2015-02-02T15:34:09Z					biological_process											owl:Class	
GO:0061198	biolink:NamedThing	fungiform papilla formation	The developmental process pertaining to the initial formation of a spongiform papilla from unspecified parts. The fungiform papilla is a mushroom-shaped papilla of the tongue.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-07-27T12:29:03Z					biological_process											owl:Class	
GO:1990773	biolink:NamedThing	matrix metallopeptidase secretion	The regulated release of matrix metallopeptidases, a family of zinc-dependent endopeptidases that can degrade extracellular matrix proteins and process other types of proteins.	tmpzr1t_l9r_go_relaxed.owl	matrix metalloproteinase secretion|MMP secretion							sl	2015-06-15T19:12:06Z					biological_process											owl:Class	
GO:0003238	biolink:NamedThing	conus arteriosus development	The progression of the conus arteriosus over time, from its formation to the mature structure. The conus arteriosus is a valved chamber with thick muscular walls stemming from the ventricle and connecting to the pulmonary trunk.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-10-13T11:20:57Z					biological_process											owl:Class	
GO:0018722	biolink:NamedThing	1-phenanthrol sulfotransferase activity	Catalysis of the reaction: 1-phenanthrol + X-SO3(-) = HX + 1-phenanthrylsulfate.	tmpzr1t_l9r_go_relaxed.owl	1-phenanthrol sulphotransferase activity				UM-BBD_reactionID:r0565									molecular_function											owl:Class	
GO:1904626	biolink:NamedThing	positive regulation of glycine secretion, neurotransmission	Any process that activates or increases the frequency, rate or extent of glycine secretion, neurotransmission.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of glycine secretion, neurotransmission|activation of glycine secretion, neurotransmission|up regulation of glycine secretion, neurotransmission|upregulation of glycine secretion, neurotransmission							hjd	2015-08-27T20:03:49Z					biological_process											owl:Class	
GO:0002854	biolink:NamedThing	positive regulation of T cell mediated cytotoxicity directed against tumor cell target	Any process that activates or increases the frequency, rate, or extent of T cell mediated cytotoxicity directed against a tumor cell target.	tmpzr1t_l9r_go_relaxed.owl	up regulation of T cell mediated cytotoxicity directed against tumor cell target|activation of T cell mediated cytotoxicity directed against tumor cell target|stimulation of T cell mediated cytotoxicity directed against tumor cell target|up-regulation of T cell mediated cytotoxicity directed against tumor cell target|upregulation of T cell mediated cytotoxicity directed against tumor cell target													biological_process											owl:Class	
GO:0009706	biolink:NamedThing	chloroplast inner membrane	The inner, i.e. lumen-facing, lipid bilayer of the chloroplast envelope; also faces the chloroplast stroma.	tmpzr1t_l9r_go_relaxed.owl	chloroplast inner envelope													cellular_component											owl:Class	
GO:1904702	biolink:NamedThing	regulation of protein localization to adherens junction	Any process that modulates the frequency, rate or extent of protein localization to adherens junction. An adherens junction is a cell-cell junction composed of the epithelial cadherin-catenin complex at which the cytoplasmic face of the plasma membrane is attached to actin filaments.	tmpzr1t_l9r_go_relaxed.owl	regulation of protein localization in cell-cell adherens junction|regulation of protein localisation in cell-cell adherens junction|regulation of protein localisation to cell-cell adherens junction							kmv	2015-10-01T15:11:49Z					biological_process											owl:Class	
GO:1902196	biolink:NamedThing	isovaleryl-CoA(4-) catabolic process	The chemical reactions and pathways resulting in the breakdown of isovaleryl-CoA(4-).	tmpzr1t_l9r_go_relaxed.owl	isovaleryl-CoA(4-) breakdown|isovaleryl-CoA(4-) degradation|isovaleryl-CoA(4-) catabolism							ms	2013-06-06T09:56:00Z					biological_process											owl:Class	
GO:0001195	biolink:NamedThing	maintenance of transcriptional fidelity during DNA-templated transcription elongation from RNA polymerase III promoter	Suppression of the occurrence of transcriptional errors, such as substitutions and/or insertions of nucleotides that do not correctly match the template base, during the process of transcription elongation from a RNA polymerase III promoter.	tmpzr1t_l9r_go_relaxed.owl	maintenance of transcriptional fidelity during DNA-dependent transcription elongation from RNA polymerase III promoter							krc	2011-09-02T02:41:29Z					biological_process											owl:Class	
GO:0001192	biolink:NamedThing	maintenance of transcriptional fidelity during DNA-templated transcription elongation	Suppression of the occurrence of transcriptional errors, such as substitutions and/or insertions of nucleotides that do not correctly match the template base, during the process of transcription elongation on a DNA template.	tmpzr1t_l9r_go_relaxed.owl	maintenance of transcriptional fidelity during DNA-dependent transcription elongation|maintenance of transcriptional fidelity during DNA-dependent transcription elongation from bacterial-type RNA polymerase promoter|maintenance of transcriptional fidelity during DNA-templated transcription elongation from bacterial-type RNA polymerase promoter							krc	2011-09-02T02:25:30Z			GO:0001194		biological_process											owl:Class	
GO:0051459	biolink:NamedThing	regulation of corticotropin secretion	Any process that modulates the frequency, rate or extent of the regulated release of corticotropic hormone from a cell.	tmpzr1t_l9r_go_relaxed.owl	regulation of corticotropic hormone secretion|regulation of adrenotropin hormone secretion|regulation of ACTH secretion|regulation of adrenocorticotropic hormone secretion|regulation of adrenotropin secretion|regulation of adrenocorticotropin secretion													biological_process											owl:Class	
GO:0106254	biolink:NamedThing	lipid sensor activity	Binding to and responding, e.g. by conformational change, to changes in the cellular level of a lipid.	tmpzr1t_l9r_go_relaxed.owl								hjd	2020-03-09T17:36:09Z					molecular_function											owl:Class	
GO:0032420	biolink:NamedThing	stereocilium	An actin-based protrusion from the apical surface of auditory and vestibular hair cells and of neuromast cells. These protrusions are supported by a bundle of cross-linked actin filaments (an actin cable), oriented such that the plus (barbed) ends are at the tip of the protrusion, capped by a tip complex which bridges to the plasma. Bundles of stereocilia act as mechanosensory organelles.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:1903437	biolink:NamedThing	negative regulation of mitotic cytokinetic process	Any process that stops, prevents or reduces the frequency, rate or extent of mitotic cytokinetic process.	tmpzr1t_l9r_go_relaxed.owl	inhibition of mitotic cytokinetic process|downregulation of mitotic cytokinetic process|down-regulation of mitotic cytokinetic process|down regulation of mitotic cytokinetic process							tb	2014-09-15T23:11:47Z					biological_process											owl:Class	
GO:0052403	biolink:NamedThing	negative regulation by host of symbiont catalytic activity	Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of symbiont enzyme activity. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	down-regulation by host of symbiont enzyme activity|downregulation by host of symbiont enzyme activity|inhibition of symbiont enzyme activity|down-regulation by host of symbiont protein function|inhibition by host of symbiont enzyme activity|inhibition of symbiont protein function|inhibition by host of symbiont protein function|down regulation by host of symbiont enzyme activity|negative regulation by host of symbiont molecular function|down regulation by host of symbiont protein function|negative regulation by host of symbiont enzyme activity|downregulation by host of symbiont protein function											GO:0052405		biological_process											owl:Class	
GO:0052422	biolink:NamedThing	modulation by host of symbiont catalytic activity	The process in which a host organism effects a change in the enzyme activity of its symbiont organism.	tmpzr1t_l9r_go_relaxed.owl	modulation by host of symbiont molecular function|modulation by host of symbiont enzyme activity											GO:0052428		biological_process											owl:Class	
GO:0060895	biolink:NamedThing	retinoic acid receptor signaling pathway involved in spinal cord dorsal/ventral patterning	The series of molecular signals generated as a consequence of a retinoic acid receptor binding to one of its physiological ligands that contributes to the dorsal ventral patterning of the spinal cord.	tmpzr1t_l9r_go_relaxed.owl	retinoic acid receptor signalling pathway involved in spinal cord dorsal/ventral patterning							dph	2009-08-13T01:51:50Z					biological_process											owl:Class	
GO:0007427	biolink:NamedThing	epithelial cell migration, open tracheal system	The orderly movement of epithelial cells during development of an open tracheal system. An example of this is found in Drosophila melanogaster.	tmpzr1t_l9r_go_relaxed.owl	tracheal cell migration|tracheal epithelial cell migration													biological_process											owl:Class	
GO:0060443	biolink:NamedThing	mammary gland morphogenesis	The process in which anatomical structures of the mammary gland are generated and organized. Morphogenesis refers to the creation of shape. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0061274	biolink:NamedThing	mesonephric distal tubule development	The process whose specific outcome is the progression of the mesonephric distal tubule over time, from its formation to the mature structure. The mesonephric distal tubule is a mesonephric nephron tubule that begins at the terminal segment of the proximal tubule and ends at the mesonephric connecting tubule.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-09-02T12:16:25Z					biological_process											owl:Class	
GO:0072017	biolink:NamedThing	distal tubule development	The process whose specific outcome is the progression of the distal tubule over time, from its formation to the mature structure. In mammals, the distal tubule is a nephron tubule that begins at the macula densa and extends to the connecting tubule.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-01-25T02:34:19Z					biological_process											owl:Class	
GO:0006041	biolink:NamedThing	glucosamine metabolic process	The chemical reactions and pathways involving glucosamine (2-amino-2-deoxyglucopyranose), an aminodeoxysugar that occurs in combined form in chitin.	tmpzr1t_l9r_go_relaxed.owl	chitosamine metabolic process|glucosamine metabolism|chitosamine metabolism													biological_process											owl:Class	
GO:0098593	biolink:NamedThing	goblet cell theca	A cup shaped specialization of the cytoskeleton that forms a thin layer located just below the apical mass of mature mucin secretory granules in the cytoplasm of goblet cells of the intestinal epithelium.  It consists of an orderly network of intermediate filaments and microtubules. Microtubules are arranged vertically, like barrel staves, along the inner aspect of the theta. Intermediate filaments form two networks: an inner, basketlike network and an outer series of circumferential bundles resembling the hoops of a barrel.	tmpzr1t_l9r_go_relaxed.owl								dos	2014-03-11T14:52:33Z					cellular_component											owl:Class	
GO:0090721	biolink:NamedThing	primary adaptive immune response involving T cells and B cells	An adaptive immune response mediated by naive T or B cells against an antigen not previously encountered by immune system.	tmpzr1t_l9r_go_relaxed.owl								tb	2016-11-11T12:46:29Z					biological_process											owl:Class	
GO:0090720	biolink:NamedThing	primary adaptive immune response	An adaptive immune response against an antigen not previously encountered by immune system.	tmpzr1t_l9r_go_relaxed.owl								tb	2016-11-11T12:44:55Z					biological_process											owl:Class	
GO:0002319	biolink:NamedThing	memory B cell differentiation	The process in which a B cell acquires the specialized features of a memory B cell. Memory B cells are cells that can respond rapidly to antigen re-exposure by production of high-affinity antibody.	tmpzr1t_l9r_go_relaxed.owl	memory B cell development|memory B-lymphocyte differentiation|memory B lymphocyte differentiation|memory B-cell differentiation					Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.								biological_process											owl:Class	
GO:0061132	biolink:NamedThing	pancreas induction	The close range interaction of two or more cells or tissues that causes the cells of the gut to change their fates and specify the development of the pancreas.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-05-17T09:45:32Z					biological_process											owl:Class	
GO:0045786	biolink:NamedThing	negative regulation of cell cycle	Any process that stops, prevents or reduces the rate or extent of progression through the cell cycle.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of progression through cell cycle|down-regulation of progression through cell cycle|inhibition of progression through cell cycle|down regulation of progression through cell cycle|negative regulation of cell cycle progression|downregulation of progression through cell cycle													biological_process											owl:Class	
GO:0047886	biolink:NamedThing	farnesol dehydrogenase activity	Catalysis of the reaction: 2-trans,6-trans-farnesol + NADP(+) = 2-trans,6-trans-farnesal + H(+) + NADPH.	tmpzr1t_l9r_go_relaxed.owl	farnesol (nicotinamide adenine dinucleotide phosphate) dehydrogenase activity|2-trans,6-trans-farnesol:NADP+ 1-oxidoreductase activity|NADP-farnesol dehydrogenase activity				MetaCyc:FARNESOL-DEHYDROGENASE-RXN|EC:1.1.1.216|RHEA:14697|KEGG_REACTION:R03264									molecular_function											owl:Class	
GO:0050929	biolink:NamedThing	induction of negative chemotaxis	Any process that initiates the directed movement of a motile cell or organism towards a lower concentration in a concentration gradient of a specific chemical.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0032329	biolink:NamedThing	serine transport	The directed movement of L-serine, 2-amino-3-hydroxypropanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	serine import							tb	2012-10-01T11:10:51Z			GO:0090478		biological_process											owl:Class	
GO:0002587	biolink:NamedThing	negative regulation of antigen processing and presentation of peptide antigen via MHC class II	Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class II.	tmpzr1t_l9r_go_relaxed.owl	downregulation of antigen processing and presentation of peptide antigen via MHC class II|down-regulation of antigen processing and presentation of peptide antigen via MHC class II|inhibition of antigen processing and presentation of peptide antigen via MHC class II|negative regulation of peptide antigen processing and presentation via MHC class II|down regulation of antigen processing and presentation of peptide antigen via MHC class II													biological_process											owl:Class	
GO:0098753	biolink:NamedThing	anchored component of the cytoplasmic side of the plasma membrane	The component of the plasma membrane consisting of gene products and protein complexes with covalently attached hydrophobic anchors products that penetrate only the cytoplasmic side of the membrane.	tmpzr1t_l9r_go_relaxed.owl						Examples include many myristoylated proteins.								cellular_component											owl:Class	
GO:0080131	biolink:NamedThing	hydroxyjasmonate sulfotransferase activity	Catalysis of the reaction: a hydroxyjasmonate + 3'-phosphoadenosine-5'-phosphosulfate = a hydroxyjasmonate sulfate + adenosine-3',5'-diphosphate.	tmpzr1t_l9r_go_relaxed.owl	11-hydroxyjasmonic acid sulfotransferase activity|12-hydroxyjasmonic acid sulfotransferase activity|OHJA sulfotransferase activity|hydroxyjasmonic acid sulfotransferase activity|12-hydroxyjasmonate sulfotransferase activity|11-OHJA sulfotransferase activity|12-OHJA sulfotransferase activity|11-hydroxyjasmonate sulfotransferase activity							dhl	2009-04-29T03:47:12Z					molecular_function											owl:Class	
GO:0010491	biolink:NamedThing	UTP:arabinose-1-phosphate uridylyltransferase activity	Catalysis of the reaction: alpha-L-arabinose 1-phosphate + UTP = UDP-L-arabinose + diphosphate.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0051748	biolink:NamedThing	UTP-monosaccharide-1-phosphate uridylyltransferase activity	Catalysis of the reaction: UTP + a monosaccharide 1-phosphate = diphosphate + UDP-monosaccharide.	tmpzr1t_l9r_go_relaxed.owl	UDP-sugar pyrophosphorylase activity|UDP-monosaccharide pyrophosphorylase activity|USP|PsUSP|UDP-monosaccharide diphosphorylase activity				RHEA:13205|MetaCyc:2.7.7.64-RXN|EC:2.7.7.64									molecular_function											owl:Class	
GO:0140325	biolink:NamedThing	negative regulation of protein localization to medial cortex	Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to the medial cortex.	tmpzr1t_l9r_go_relaxed.owl								pg	2019-04-17T11:58:27Z					biological_process											owl:Class	
GO:0010370	biolink:NamedThing	perinucleolar chromocenter	A chromocenter adjacent to the nucleolus.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0010369	biolink:NamedThing	chromocenter	A region in which centric, heterochromatic portions from more than one chromosomes form a compact structure.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0000374	biolink:NamedThing	Group III intron splicing	The splicing of Group III introns. This occurs by a ribozymic mechanism where the intron sequence forms a distinct 3D structure, characteristic of Group III introns, that is involved in catalyzing the splicing reactions, though protein factors are also required in vivo. Splicing occurs by a series of two transesterification reactions begun by a bulged adenosine residue within the intron sequence as the initiating nucleophile. The intron is excised as a lariat. Though very similar in structure and mechanism to Group II introns, Group III introns are smaller and more streamlined and the splice site consensus sequences are not as well conserved.	tmpzr1t_l9r_go_relaxed.owl	mRNA splicing					Note that Group III introns are known to be found in mRNA of plastids of euglenoid protists.								biological_process											owl:Class	
GO:0097130	biolink:NamedThing	cyclin D3-CDK4 complex	A protein complex consisting of cyclin D3 and cyclin-dependent kinase 4 (CDK4). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner.	tmpzr1t_l9r_go_relaxed.owl								pr	2011-08-01T01:54:17Z					cellular_component											owl:Class	
GO:0070537	biolink:NamedThing	histone H2A K63-linked deubiquitination	A protein deubiquitination process in which a K63-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 63 of the ubiquitin monomers, is removed from a lysine residue in histone H2A or the variant H2AX.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0005838	biolink:NamedThing	proteasome regulatory particle	A multisubunit complex, which caps one or both ends of the proteasome core complex. This complex recognizes and unfolds ubiquitinated proteins, and translocates them to the proteasome core complex.	tmpzr1t_l9r_go_relaxed.owl	PA700 proteasome activator|19S regulatory particle|PA700-dependent proteasome activator|modulator complex													cellular_component											owl:Class	
GO:0097571	biolink:NamedThing	left nucleus	One of the two nuclei found in Giardia species (trophozoite stage). It is located on the left side of the cell when viewed from the dorsal side.	tmpzr1t_l9r_go_relaxed.owl						Due to the asymmetric nature of the Giardia trophozoite, this term is defined spatially as the trophozoite is viewed from the dorsal side, with the two nuclei dorsal to the ventral disc, and the ventral disc toward the anterior.		pr	2014-02-18T11:21:31Z					cellular_component											owl:Class	
GO:0070137	biolink:NamedThing	ubiquitin-like protein-specific endopeptidase activity	Catalysis of the hydrolysis of peptide bonds between an alpha-carboxyl group and an alpha-amino group within a small protein such as ubiquitin or a ubiquitin-like protein (e.g. APG8, ISG15, NEDD8, SUMO).	tmpzr1t_l9r_go_relaxed.owl	small conjugating protein-specific endopeptidase activity													molecular_function											owl:Class	
GO:0033502	biolink:NamedThing	cellular galactose homeostasis	A cellular homeostatic process involved in the maintenance of an internal steady state of galactose within a cell or between a cell and its external environment.	tmpzr1t_l9r_go_relaxed.owl	cell galactose homeostasis													biological_process											owl:Class	
GO:0048058	biolink:NamedThing	compound eye corneal lens development	The process whose specific outcome is the progression of the corneal lens in the compound eye over time, from its formation to the mature structure. The corneal lens is a chitinous extracellular secretion of the four underlying cone cells and the pigment cells.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0052768	biolink:NamedThing	mannosyl-oligosaccharide 1,3-alpha-mannosidase activity	Catalysis of the hydrolysis of the alpha-(1->3) bonds of alpha-D-mannose residues in mannosyl-oligosaccharide.	tmpzr1t_l9r_go_relaxed.owl	1,3-alpha-mannosidase activity|1,3-alpha-mannosyl-oligosaccharide alpha-D-mannohydrolase activity|alpha-1,3-mannosyl-oligosaccharide alpha-D-mannohydrolase activity|alpha-1,3-mannosidase activity				EC:3.1.1.-			ai	2011-09-30T12:55:24Z					molecular_function											owl:Class	
GO:0015924	biolink:NamedThing	mannosyl-oligosaccharide mannosidase activity	Catalysis of the hydrolysis of the terminal alpha-D-mannose residues in oligo-mannose oligosaccharides.	tmpzr1t_l9r_go_relaxed.owl					EC:3.2.1.-									molecular_function											owl:Class	
GO:0098507	biolink:NamedThing	polynucleotide 5' dephosphorylation	The process of removing one or more phosphate groups from the 5' end of a polynucleotide.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:2000768	biolink:NamedThing	positive regulation of nephron tubule epithelial cell differentiation	Any process that activates or increases the frequency, rate or extent of nephron tubule epithelial cell differentiation.	tmpzr1t_l9r_go_relaxed.owl								yaf	2011-06-22T11:55:06Z					biological_process											owl:Class	
GO:0071389	biolink:NamedThing	cellular response to mineralocorticoid stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mineralocorticoid stimulus. Mineralocorticoids are hormonal C21 corticosteroids synthesized from cholesterol and characterized by their similarity to aldosterone. Mineralocorticoids act primarily on water and electrolyte balance.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-12-11T03:59:02Z					biological_process											owl:Class	
GO:0060963	biolink:NamedThing	positive regulation of ribosomal protein gene transcription by RNA polymerase II	Any process that increases the frequency, rate or extent of the synthesis of RNA from ribosomal protein genes mediated by RNA polymerase II.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of ribosomal protein gene transcription from RNA polymerase II promoter							dph	2009-10-05T03:04:05Z					biological_process											owl:Class	
GO:0020002	biolink:NamedThing	host cell plasma membrane	The plasma membrane surrounding a host cell.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:1904564	biolink:NamedThing	Nbp35-Cfd1 ATPase complex	An iron-sulfur cluster assembly complex that is capable of weak ATPase activity. In yeast it consists of two subunits, Nbp35 and Cfd1.	tmpzr1t_l9r_go_relaxed.owl								rb	2015-08-18T22:50:29Z					cellular_component											owl:Class	
GO:1904831	biolink:NamedThing	positive regulation of aortic smooth muscle cell differentiation	Any process that activates or increases the frequency, rate or extent of aortic smooth muscle cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of aortic smooth muscle cell differentiation|activation of aortic smooth muscle cell differentiation|upregulation of aortic smooth muscle cell differentiation|up regulation of aortic smooth muscle cell differentiation							rph	2015-11-24T10:20:54Z					biological_process											owl:Class	
GO:1990052	biolink:NamedThing	ER to chloroplast lipid transport	The directed movement of a lipid from the endoplasmic reticulum (ER) to the chloroplast.	tmpzr1t_l9r_go_relaxed.owl	endoplasmic reticulum to chloroplast lipid transport|ER to chloroplast lipid trafficking							tb	2013-02-22T00:05:23Z					biological_process											owl:Class	
GO:0061925	biolink:NamedThing	negative regulation of formation of radial glial scaffolds	Any process that reduces the frequency, rate or extent of the formation of radial glial scaffolds. The scaffolds are used as a substrate for the radial migration of cells.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of Bergmann fiber formation|negative regulation of Bergmann fiber biosynthesis|negative regulation of radial glial scaffold formation							dph	2017-08-02T16:24:27Z					biological_process											owl:Class	
GO:0060865	biolink:NamedThing	negative regulation of floral organ abscission by transmembrane receptor protein serine/threonine kinase signaling pathway	The series of molecular signals generated as a consequence of a transmembrane receptor serine/threonine kinase binding to its physiological ligand and contributing to the decrease in the rate or frequency of floral organ abscission.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of floral organ abscission by transmembrane receptor protein serine/threonine kinase signalling pathway							dph	2009-08-12T04:42:14Z					biological_process											owl:Class	
GO:0035665	biolink:NamedThing	TIRAP-dependent toll-like receptor 4 signaling pathway	Any series of molecular signals generated as a consequence of binding to a toll-like receptor 4 where the TIRAP/MAL adaptor mediates transduction of the signal. Toll-like 4 receptors are pattern recognition receptors that bind bacterial lipopolysaccharide (LPS) to initiate an innate immune response.	tmpzr1t_l9r_go_relaxed.owl	MyD88 adapter-like dependent toll-like receptor 4 signaling pathway|MAL-dependent toll-like receptor 4 signaling pathway|TIRAP-dependent toll-like receptor 4 signalling pathway|TIRAP-dependent TLR4 signaling pathway							bf	2011-02-01T02:33:48Z					biological_process											owl:Class	
GO:0035664	biolink:NamedThing	TIRAP-dependent toll-like receptor signaling pathway	Any series of molecular signals generated as a consequence of binding to a toll-like receptor where the TIRAP/MAL adaptor mediates transduction of the signal. Toll-like receptors directly bind pattern motifs from a variety of microbial sources to initiate innate immune response.	tmpzr1t_l9r_go_relaxed.owl	MAL-dependent toll-like receptor signaling pathway|MyD88 adapter-like dependent toll-like receptor signaling pathway|TIRAP-dependent TLR signaling pathway|TIRAP-dependent toll-like receptor signalling pathway							bf	2011-02-01T02:31:37Z					biological_process											owl:Class	
GO:0098534	biolink:NamedThing	centriole assembly	A cellular process that results in the assembly of one or more centrioles.	tmpzr1t_l9r_go_relaxed.owl								dos	2013-10-22T15:55:22Z					biological_process											owl:Class	
GO:0086071	biolink:NamedThing	atrial cardiac muscle cell-AV node cell adhesion involved in cell communication	The attachment of an atrial cardiomyocyte to an AV node cell via adhesion molecules that results in the cells being juxtaposed so that they can communicate.	tmpzr1t_l9r_go_relaxed.owl	atrial cardiomyocyte-atrioventricular node cell adhesion involved in cell communication|atrial cardiomyocyte-AV node cell adhesion involved in cell communication							dph	2011-11-22T09:46:33Z					biological_process											owl:Class	
GO:0034113	biolink:NamedThing	heterotypic cell-cell adhesion	The attachment of a cell to a cell of a different type via adhesion molecules.	tmpzr1t_l9r_go_relaxed.owl						Note that this term is not synonymous with 'heterophilic cell adhesion ; GO:0007157'; the process may occur by homophilic or heterophilic mechanisms.								biological_process											owl:Class	
GO:0140663	biolink:NamedThing	ATP-dependent FeS chaperone activity	Binding to and delivering metal ions to a target protein, driven by ATP hydrolysis.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/21661						pg	2021-06-19T16:33:09Z					molecular_function											owl:Class	
GO:0044616	biolink:NamedThing	modulation of relaxation of muscle in other organism	The process in which an organism effects a change in the relaxation of muscle in a second organism.	tmpzr1t_l9r_go_relaxed.owl	regulation of relaxation of muscle in other organism							jl	2012-07-04T01:54:12Z					biological_process											owl:Class	
GO:0046676	biolink:NamedThing	negative regulation of insulin secretion	Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of insulin.	tmpzr1t_l9r_go_relaxed.owl	downregulation of insulin secretion|down regulation of insulin secretion|down-regulation of insulin secretion|inhibition of insulin secretion													biological_process											owl:Class	
GO:0047763	biolink:NamedThing	caffeate O-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + 3,4-dihydroxy-trans-cinnamate = S-adenosyl-L-homocysteine + 3-methoxy-4-hydroxy-trans-cinnamate.	tmpzr1t_l9r_go_relaxed.owl	S-adenosyl-L-methionine:3,4-dihydroxy-trans-cinnamate 3-O-methyltransferase activity|caffeate 3-O-methyltransferase activity|S-adenosyl-L-methionine:caffeic acid-O-methyltransferase activity|caffeate methyltransferase activity				RHEA:20225|MetaCyc:RXN-1104|EC:2.1.1.68									molecular_function											owl:Class	
GO:0016995	biolink:NamedThing	cholesterol oxidase activity	Catalysis of the reaction: cholesterol + O2 = cholest-5-en-3-one + H2O2.	tmpzr1t_l9r_go_relaxed.owl	3beta-hydroxysteroid:oxygen oxidoreductase activity|cholesterol-O(2) oxidoreductase activity|3beta-hydroxy steroid oxidoreductase activity|cholesterol:oxygen oxidoreductase activity|cholesterol- O2 oxidoreductase activity|cholesterol-O2 oxidoreductase activity				EC:1.1.3.6|MetaCyc:CHOLESTEROL-OXIDASE-RXN|KEGG_REACTION:R01459|RHEA:32183									molecular_function											owl:Class	
GO:0048698	biolink:NamedThing	negative regulation of collateral sprouting in absence of injury	Any process that stops, prevents, or reduces the frequency, rate or extent of collateral sprouting in the absence of injury.	tmpzr1t_l9r_go_relaxed.owl	down regulation of collateral sprouting in the absence of injury|inhibition of collateral sprouting in the absence of injury|down-regulation of collateral sprouting in the absence of injury|downregulation of collateral sprouting in the absence of injury													biological_process											owl:Class	
GO:0048696	biolink:NamedThing	regulation of collateral sprouting in absence of injury	Any process that modulates the frequency, rate or extent of collateral sprouting in the absence of injury.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0021822	biolink:NamedThing	negative regulation of cell motility involved in cerebral cortex radial glia guided migration	The intracellular signaling pathway that results in the cessation of cell movement involved in lamination of the cerebral cortex.	tmpzr1t_l9r_go_relaxed.owl	down regulation of cell locomotion involved in cerebral cortex glial-mediated radial cell migration|negative regulation of cell locomotion involved in cerebral cortex radial glia guided migration|inhibition of cell locomotion involved in cerebral cortex glial-mediated radial cell migration|down-regulation of cell locomotion involved in cerebral cortex glial-mediated radial cell migration|downregulation of cell locomotion involved in cerebral cortex glial-mediated radial cell migration|negative regulation of cell locomotion involved in cerebral cortex glial-mediated radial migration													biological_process											owl:Class	
GO:0015549	biolink:NamedThing	carbonyl cyanide m-chlorophenylhydrazone transmembrane transporter activity	Enables the transfer of carbonyl cyanide m-chlorophenylhydrazone from one side of a membrane to the other. Carbonyl cyanide m-chlorophenylhydrazone is a proton ionophore, commonly used as an uncoupling agent and inhibitor of photosynthesis because of its effects on mitochondrial and chloroplast membranes.	tmpzr1t_l9r_go_relaxed.owl	CCCP transporter activity|carbonyl cyanide m-chlorophenylhydrazone/nalidixic acid/organomercurials:hydrogen antiporter activity|carbonyl cyanide m-chlorophenylhydrazone transporter activity													molecular_function											owl:Class	
GO:0033966	biolink:NamedThing	N-substituted formamide deformylase activity	Catalysis of the reaction: N-benzylformamide + H2O = formate + benzylamine.	tmpzr1t_l9r_go_relaxed.owl	NfdA|N-benzylformamide amidohydrolase activity				RHEA:12096|MetaCyc:3.5.1.91-RXN									molecular_function											owl:Class	
GO:0035601	biolink:NamedThing	protein deacylation	The removal of an acyl group, any group or radical of the form RCO- where R is an organic group, from a protein amino acid.	tmpzr1t_l9r_go_relaxed.owl	protein amino acid deacylation							bf	2010-11-15T11:06:15Z					biological_process											owl:Class	
GO:0098732	biolink:NamedThing	macromolecule deacylation	The removal of an acyl group, any group or radical of the form RCO- where R is an organic group, from a macromolecule.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1905491	biolink:NamedThing	positive regulation of sensory neuron axon guidance	Any process that activates or increases the frequency, rate or extent of sensory neuron axon guidance.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of sensory neuron axon guidance|activation of sensory neuron axon guidance|upregulation of sensory neuron axon guidance|up regulation of sensory neuron axon guidance							hbye	2016-09-23T13:19:12Z					biological_process											owl:Class	
GO:0030555	biolink:NamedThing	RNA modification guide activity	Specifies the site of a posttranscriptional modification in an RNA molecule by base pairing with a short sequence around the target residue.	tmpzr1t_l9r_go_relaxed.owl						Note that this term describes the activity of a nucleic acid, usually RNA, gene product that interacts with other RNA molecules via base pairing; it should not be used to annotate proteins.								molecular_function											owl:Class	
GO:1904860	biolink:NamedThing	DNA synthesis involved in mitotic DNA replication	Any DNA biosynthetic process that is involved in mitotic DNA replication.	tmpzr1t_l9r_go_relaxed.owl	DNA anabolism involved in DNA replication during S phase involved in mitotic cell cycle|DNA synthesis involved in mitotic cell cycle DNA replication|DNA biosynthetic process involved in DNA replication involved in S phase involved in mitotic cell cycle|DNA synthesis involved in DNA replication involved in S-phase involved in mitotic cell cycle|DNA synthesis involved in nuclear cell cycle DNA replication involved in mitotic cell cycle|DNA biosynthetic process involved in DNA replication during S phase involved in mitotic cell cycle|DNA biosynthetic process involved in nuclear cell cycle DNA replication involved in mitotic cell cycle|DNA biosynthesis involved in mitotic DNA replication|DNA anabolism involved in mitotic DNA replication|DNA anabolism involved in DNA replication involved in S-phase involved in mitotic cell cycle|DNA biosynthesis involved in DNA replication involved in S-phase involved in mitotic cell cycle|DNA synthesis involved in mitotic nuclear cell cycle DNA replication|DNA biosynthesis involved in nuclear cell cycle DNA replication involved in mitotic cell cycle|DNA formation involved in DNA replication involved in S-phase involved in mitotic cell cycle|DNA formation involved in mitotic DNA replication|DNA formation involved in DNA replication involved in S phase involved in mitotic cell cycle|DNA biosynthesis involved in mitotic nuclear cell cycle DNA replication|DNA biosynthesis involved in DNA replication during S phase involved in mitotic cell cycle|DNA synthesis involved in DNA replication involved in S phase involved in mitotic cell cycle|DNA anabolism involved in mitotic cell cycle DNA replication|DNA biosynthetic process involved in mitotic nuclear cell cycle DNA replication|DNA anabolism involved in nuclear cell cycle DNA replication involved in mitotic cell cycle|DNA biosynthesis involved in mitotic cell cycle DNA replication|DNA formation involved in DNA replication during S phase involved in mitotic cell cycle|DNA synthesis involved in DNA replication during S phase involved in mitotic cell cycle|DNA biosynthetic process involved in mitotic cell cycle DNA replication|DNA formation involved in mitotic cell cycle DNA replication|DNA biosynthetic process involved in mitotic DNA replication|DNA biosynthetic process involved in DNA replication involved in S-phase involved in mitotic cell cycle|DNA formation involved in mitotic nuclear cell cycle DNA replication|DNA formation involved in nuclear cell cycle DNA replication involved in mitotic cell cycle|DNA biosynthesis involved in DNA replication involved in S phase involved in mitotic cell cycle|DNA anabolism involved in DNA replication involved in S phase involved in mitotic cell cycle|DNA anabolism involved in mitotic nuclear cell cycle DNA replication							mah	2015-12-16T12:02:37Z					biological_process											owl:Class	
GO:0036173	biolink:NamedThing	thiosulfate binding	Binding to a thiosulfate, a sulfur oxide that has formula O3S2.	tmpzr1t_l9r_go_relaxed.owl								bf	2012-03-29T10:38:15Z					molecular_function											owl:Class	
GO:0035149	biolink:NamedThing	lumen formation, open tracheal system	Creation of the central hole of a tube in an open tracheal system through which gases flow.	tmpzr1t_l9r_go_relaxed.owl	tracheal lumen formation													biological_process											owl:Class	
GO:0097377	biolink:NamedThing	spinal cord interneuron axon guidance	The process in which the migration of an axon growth cone of a spinal cord interneuron is directed to a specific target site in response to a combination of attractive and repulsive cues. A spinal cord interneuron is a CNS interneuron located in the spinal cord.	tmpzr1t_l9r_go_relaxed.owl								pr	2012-10-01T10:19:42Z					biological_process											owl:Class	
GO:0097376	biolink:NamedThing	interneuron axon guidance	The process in which the migration of an axon growth cone of an interneuron is directed to a specific target site in response to a combination of attractive and repulsive cues. An interneuron is any neuron which is not motor or sensory. Interneurons may also refer to neurons whose axons remain within a particular brain region, as contrasted with projection neurons which have axons projecting to other brain regions.	tmpzr1t_l9r_go_relaxed.owl								pr	2012-10-01T10:18:35Z					biological_process											owl:Class	
GO:0038115	biolink:NamedThing	chemokine (C-C motif) ligand 19 signaling pathway	A series of molecular signals initiated by the binding of the C-C chemokine CCL19 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.	tmpzr1t_l9r_go_relaxed.owl	C-C chemokine receptor type 7 signaling pathway|chemokine (C-C motif) ligand 19 signalling pathway|CCL19-mediated signaling pathway					The C-C chemokine CCL19 s a known agonist of the chemokine receptor type 7 (CCR7). Consider instead annotating to the child term 'CCL19-activated CCR7 signaling pathway ; GO:0038119'.		bf	2012-03-22T11:28:32Z					biological_process											owl:Class	
GO:0000303	biolink:NamedThing	response to superoxide	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a superoxide stimulus. Superoxide is the anion, oxygen-, formed by addition of one electron to dioxygen (O2) or any compound containing the superoxide anion.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0000305	biolink:NamedThing	response to oxygen radical	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxygen radical stimulus. An oxygen radical is any oxygen species that carries a free electron; examples include hydroxyl radicals and the superoxide anion.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0033568	biolink:NamedThing	lactoferrin receptor activity	Combining with lactoferrin and delivering lactoferrin into the cell via endocytosis. Lactoferrin is an iron-binding glycoprotein which binds ferric iron most efficiently at low pH.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0099003	biolink:NamedThing	vesicle-mediated transport in synapse	Any vesicle-mediated transport that occurs in a synapse.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0003373	biolink:NamedThing	dynamin family protein polymerization involved in membrane fission	The process of creating dynamin family protein polymers, compounds composed of a large number of dynamin family protein monomers. Dynamin family protein polymers form around lipid tubes and contribute to membrane fission.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-12-09T04:55:16Z					biological_process											owl:Class	
GO:1901658	biolink:NamedThing	glycosyl compound catabolic process	The chemical reactions and pathways resulting in the breakdown of glycosyl compound.	tmpzr1t_l9r_go_relaxed.owl	glycosyl compound degradation|glycosyl compound catabolism|glycosyl compound breakdown							pr	2012-11-20T14:24:11Z					biological_process											owl:Class	
GO:0006022	biolink:NamedThing	aminoglycan metabolic process	The chemical reactions and pathways involving aminoglycans, any polymer containing amino groups that consists of more than about 10 monosaccharide residues joined to each other by glycosidic linkages.	tmpzr1t_l9r_go_relaxed.owl	aminoglycan metabolism													biological_process											owl:Class	
GO:0018336	biolink:NamedThing	peptidyl-tyrosine hydroxylation	The hydroxylation of peptidyl-tyrosine to form peptidyl-dihydroxyphenylalanine.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0045022	biolink:NamedThing	early endosome to late endosome transport	The directed movement of substances, in membrane-bounded vesicles, from the early sorting endosomes to the late sorting endosomes; transport occurs along microtubules and can be experimentally blocked with microtubule-depolymerizing drugs.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:2000526	biolink:NamedThing	positive regulation of glycoprotein biosynthetic process involved in immunological synapse formation	Any positive regulation of glycoprotein biosynthetic process that is involved in immunological synapse formation.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of glycoprotein biosynthetic process of formation of immunological synapse|positive regulation of glycoprotein biosynthetic process of immunological synapse formation							ebc	2011-03-23T10:42:30Z					biological_process											owl:Class	
GO:0050022	biolink:NamedThing	L-arabinose 1-dehydrogenase (NAD+) activity	Catalysis of the reaction: L-arabinose + NAD+ = L-arabinono-1,4-lactone + NADH.	tmpzr1t_l9r_go_relaxed.owl	L-arabinose 1-dehydrogenase activity|L-arabinose:NAD+ 1-oxidoreductase activity				EC:1.1.1.46|RHEA:17925|MetaCyc:L-ARABINOSE-1-DEHYDROGENASE-RXN									molecular_function											owl:Class	
GO:1990133	biolink:NamedThing	molybdopterin cofactor (Moco) biosynthesis adenylyltransferase complex	A heterodimeric protein complex which adenylates two molecules of the sulfur carrier subunit of the molybdopterin (MPT) cofactor synthase using ATP as part of molybdopterin cofactor (Moco) biosynthesis. In E. coli the subunits are MoeB and MoaD; Moco biosynthesis and its constituent molecules are evolutionarily conserved.	tmpzr1t_l9r_go_relaxed.owl								bhm	2013-06-26T10:54:21Z					cellular_component											owl:Class	
GO:0009111	biolink:NamedThing	vitamin catabolic process	The chemical reactions and pathways resulting in the breakdown of a vitamin, one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body.	tmpzr1t_l9r_go_relaxed.owl	vitamin breakdown|vitamin degradation|vitamin catabolism													biological_process											owl:Class	
GO:0043289	biolink:NamedThing	apocarotenoid biosynthetic process	The chemical reactions and pathways resulting in the formation of apocarotenoids by the oxidative cleavage of carotenoids. Many apocarotenoids are biologically important e.g. retinal and abscisic acid.	tmpzr1t_l9r_go_relaxed.owl	apo carotenoid biosynthetic process|apocarotenoid synthesis|apocarotenoid biosynthesis|apocarotenoid anabolism|apocarotenoid formation													biological_process											owl:Class	
GO:0034822	biolink:NamedThing	citronellal dehydrogenase activity	Catalysis of the reaction: citronellal + NAD+ + OH- = citronellate + NADH + H+.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r1156									molecular_function											owl:Class	
GO:0071761	biolink:NamedThing	IgZ immunoglobulin complex	A protein complex composed of two identical immunoglobulin heavy chains of the IgZ isotype and two identical immunoglobulin light chains, held together by disulfide bonds. The IgZ isotype is also known as the IgT isotype in certain species of fish.	tmpzr1t_l9r_go_relaxed.owl	IgT antibody|IgZ antibody|IgT immunoglobulin complex					Note that an IgZ immunoglobulin complex has the function of antigen binding if a suitable antigen is available. Note that IgZ is found in bony fish, and called IgT in certain species, such as trout.		mah	2010-03-24T01:44:53Z					cellular_component											owl:Class	
GO:0016106	biolink:NamedThing	sesquiterpenoid biosynthetic process	The chemical reactions and pathways resulting in the formation of sesquiterpenoid compounds, terpenoids with three isoprene units.	tmpzr1t_l9r_go_relaxed.owl	sesquiterpenoid biosynthesis|sesquiterpenoid synthesis|sesquiterpenoid formation|sesquiterpenoid anabolism													biological_process											owl:Class	
GO:0140028	biolink:NamedThing	pore formation during contractile vacuole discharge	The formation of a transient pore in the plasma membrane and the attached contractile vacuolar membrane, to release water from the cell. This process does not involve fusion of the two membranes.	tmpzr1t_l9r_go_relaxed.owl								pg	2017-05-15T12:20:27Z					biological_process											owl:Class	
GO:0140029	biolink:NamedThing	exocytic process	The cellular processes that contribute to exocytosis.	tmpzr1t_l9r_go_relaxed.owl								pg	2017-05-15T13:20:45Z					biological_process											owl:Class	
GO:0019180	biolink:NamedThing	dTDP-4-amino-4,6-dideoxygalactose transaminase activity	Catalysis of the reaction: 2-oxoglutarate + dTDP-4-amino-4,6-dideoxy-D-galactose = L-glutamate + dTDP-4-dehydro-6-deoxy-D-galactose.	tmpzr1t_l9r_go_relaxed.owl	dTDP-fucosamine aminotransferase activity|thymidine diphosphate 4-keto-6-deoxy-D-glucose transaminase activity|dTDP-4,6-dideoxy-D-galactose:2-oxoglutarate aminotransferase activity|dTDP-4-amino-4,6-dideoxygalactose aminotransferase activity|thymidine diphosphoaminodideoxygalactose aminotransferase activity				MetaCyc:2.6.1.59-RXN|RHEA:10368|KEGG_REACTION:R04438|EC:2.6.1.59									molecular_function											owl:Class	
GO:0009413	biolink:NamedThing	response to flooding	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating flooding, short-term immersion in water.	tmpzr1t_l9r_go_relaxed.owl						Note that this term should not be confused with 'response to deep water ; GO:0030912'. Flooding refers to short-term immersion, whereas 'response to deep water ; GO:0030912' refers to standing in water throughout an organism's life cycle.								biological_process											owl:Class	
GO:1904463	biolink:NamedThing	ergosteryl 3-beta-D-glucoside biosynthetic process	The chemical reactions and pathways resulting in the formation of ergosteryl 3-beta-D-glucoside.	tmpzr1t_l9r_go_relaxed.owl	ergosteryl 3-beta-D-glucoside synthesis|ergosteryl 3-beta-D-glucoside anabolism|ergosteryl 3-beta-D-glucoside formation|ergosteryl 3-beta-D-glucoside biosynthesis							mcc	2015-07-09T19:36:31Z					biological_process											owl:Class	
GO:1904022	biolink:NamedThing	positive regulation of G protein-coupled receptor internalization	Any process that activates or increases the frequency, rate or extent of G protein-coupled receptor internalization.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of G-protein coupled receptor internalization|positive regulation of G-protein coupled receptor internalization|upregulation of G-protein coupled receptor internalization|up regulation of G-protein coupled receptor internalization|activation of G-protein coupled receptor internalization							pga	2015-03-10T17:10:56Z					biological_process											owl:Class	
GO:0106258	biolink:NamedThing	L-serine-phosphatidylcholine phosphatidyltransferase activity	Catalysis of the reaction: a 1,2-diacyl-sn-glycero-3-phosphocholine + L-serine = 1,2-diacyl-sn-glycero-3-phospho-L-serine + choline.	tmpzr1t_l9r_go_relaxed.owl					RHEA:45088			hjd	2020-04-21T17:31:56Z					molecular_function											owl:Class	
GO:0075291	biolink:NamedThing	positive regulation of aplanospore formation	Any process that activates, maintains or increases the frequency, rate or extent of aplanospore formation, a process in which a nonmotile, asexual spore is formed within a cell in certain algae and fungi (commonly in the Phycomycetes), the wall of aplanospore is distinct from that of the parent cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0010960	biolink:NamedThing	magnesium ion homeostasis	Any process involved in the maintenance of an internal steady state of magnesium ions within an organism or cell.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-05-06T11:47:17Z					biological_process											owl:Class	
GO:0045678	biolink:NamedThing	positive regulation of R7 cell differentiation	Any process that activates or increases the frequency, rate or extent of R7 cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	activation of R7 differentiation|up-regulation of R7 differentiation|up regulation of R7 differentiation|upregulation of R7 differentiation|positive regulation of R7 differentiation|stimulation of R7 differentiation													biological_process											owl:Class	
GO:0045272	biolink:NamedThing	plasma membrane respiratory chain complex I	A subcomplex of the respiratory chain located in the plasma membrane. It contains about 25 different polypeptide subunits, including NADH dehydrogenase (ubiquinone), flavin mononucleotide and several different iron-sulfur clusters containing non-heme iron. The iron undergoes oxidation-reduction between Fe(II) and Fe(III), and catalyzes proton translocation linked to the oxidation of NADH by ubiquinone. Examples of this component are found in bacterial species.	tmpzr1t_l9r_go_relaxed.owl	NADH dehydrogenase (ubiquinone) complex|respiratory chain complex I													cellular_component											owl:Class	
GO:0047208	biolink:NamedThing	o-dihydroxycoumarin 7-O-glucosyltransferase activity	Catalysis of the reaction: 7,8-dihydroxycoumarin + UDP-D-glucose = daphnin + H(+) + UDP.	tmpzr1t_l9r_go_relaxed.owl	UDP-glucose:o-dihydroxycoumarin glucosyltransferase activity|UDPglucose:7,8-dihydroxycoumarin 7-O-beta-D-glucosyltransferase activity|UDP-glucose:7,8-dihydroxycoumarin 7-O-beta-D-glucosyltransferase activity|uridine diphosphoglucose-o-dihydroxycoumarin 7-O-glucosyltransferase activity				EC:2.4.1.104|RHEA:14325|KEGG_REACTION:R03548|MetaCyc:2.4.1.104-RXN									molecular_function											owl:Class	
GO:1904213	biolink:NamedThing	negative regulation of iodide transmembrane transport	Any process that stops, prevents or reduces the frequency, rate or extent of iodide transmembrane transport.	tmpzr1t_l9r_go_relaxed.owl	downregulation of iodide transmembrane transport|inhibition of iodide transmembrane transport|down regulation of iodide transmembrane transport|down-regulation of iodide transmembrane transport							sl	2015-05-14T19:00:08Z					biological_process											owl:Class	
GO:0048275	biolink:NamedThing	N-terminal peptidyl-arginine acetylation	The acetylation of the N-terminal arginine of proteins; catalyzed by an uncharacterized arginyl-peptide alpha-N-acetyltransferase.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0354									biological_process											owl:Class	
GO:0106391	biolink:NamedThing	bI4 intron splicing complex	A protein complex required for the splicing of intron 4 of the cytochrome b (COB) gene. In S. cerevisiae, the complex contains the maturase bI4 (which derives from one of the products of the splicing), Leucyl-tRNA synthetase NAM2 and the intron 4 of the cytochrome b pre-mRNA. The two proteins stimulate the ribozyme activity of the pre-mRNA which autoctalyse a group I intron splicing.	tmpzr1t_l9r_go_relaxed.owl					Intact:EBI-16420264			hjd	2021-10-08T14:28:33Z					cellular_component											owl:Class	
GO:0008861	biolink:NamedThing	formate C-acetyltransferase activity	Catalysis of the reaction: acetyl-CoA + formate = CoA + pyruvate.	tmpzr1t_l9r_go_relaxed.owl	pyruvic formate-lyase activity|pyruvate formate:lyase activity|pyruvate formate-lyase activity|PFL|formate acetyltransferase activity|acetyl-CoA:formate C-acetyltransferase activity				MetaCyc:PYRUVFORMLY-RXN|RHEA:11844|EC:2.3.1.54									molecular_function											owl:Class	
GO:0070628	biolink:NamedThing	proteasome binding	Binding to a proteasome, a large multisubunit protein complex that catalyzes protein degradation.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-05-01T04:38:58Z					molecular_function											owl:Class	
GO:0070593	biolink:NamedThing	dendrite self-avoidance	The process in which dendrites recognize and avoid contact with sister dendrites from the same cell.	tmpzr1t_l9r_go_relaxed.owl	dendrite repulsion							mah	2009-04-28T03:29:14Z					biological_process											owl:Class	
GO:0102485	biolink:NamedThing	dATP phosphohydrolase activity	Catalysis of the reaction: dATP + 2 H2O = dAMP + 2 hydrogenphosphate + 2 H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-14195|EC:3.6.1.5									molecular_function											owl:Class	
GO:0008388	biolink:NamedThing	testosterone 15-alpha-hydroxylase activity	Catalysis of the reaction: testosterone + donor-H2 + O2 = 15-alpha-hydroxytestosterone + H2O.	tmpzr1t_l9r_go_relaxed.owl	cytochrome P450 CYP2A4													molecular_function											owl:Class	
GO:0009522	biolink:NamedThing	photosystem I	A photosystem that contains an iron-sulfur reaction center associated with accessory pigments and electron carriers. In cyanobacteria and chloroplasts, photosystem I functions as a light-dependent plastocyanin-ferredoxin oxidoreductase, transferring electrons from plastocyanin to ferredoxin; in photosynthetic bacteria that have only a single type I photosystem, such as the green sulfur bacteria, electrons can go either to ferredoxin (Fd) -> NAD+ or to menaquinone (MK) -> Cytb/FeS -> Cytc555 -> photosystem I (cyclic photophosphorylation).	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:2000350	biolink:NamedThing	positive regulation of CD40 signaling pathway	Any process that activates or increases the frequency, rate or extent of signaling via the CD40 signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of CD40 signalling pathway							mah	2011-02-03T10:29:46Z					biological_process											owl:Class	
GO:0031965	biolink:NamedThing	nuclear membrane	Either of the lipid bilayers that surround the nucleus and form the nuclear envelope; excludes the intermembrane space.	tmpzr1t_l9r_go_relaxed.owl					NIF_Subcellular:sao1687101204									cellular_component											owl:Class	
GO:0050445	biolink:NamedThing	asparagusate reductase activity	Catalysis of the reaction: 3-mercapto-2-mercaptomethylpropanoate + NAD(+) = asparagusate + H(+) + NADH.	tmpzr1t_l9r_go_relaxed.owl	asparagusate reductase (NADH2)|3-mercapto-2-mercaptomethylpropanoate:NAD+ oxidoreductase activity|NADH2:asparagusate oxidoreductase activity|asparagusate dehydrogenase activity|asparagusate reductase (NADH) activity|NADH:asparagusate oxidoreductase activity|asparagusic dehydrogenase activity				RHEA:14881|MetaCyc:ASPARAGUSATE-REDUCTASE-NADH-RXN|KEGG_REACTION:R03761|EC:1.8.1.11									molecular_function											owl:Class	
GO:0060523	biolink:NamedThing	prostate epithelial cord elongation	The developmental growth process in which solid chords of prostate epithelium increase in length.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1900171	biolink:NamedThing	positive regulation of glucocorticoid mediated signaling pathway	Any process that activates or increases the frequency, rate or extent of glucocorticoid mediated signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	activation of glucocorticoid mediated signaling pathway|up regulation of glucocorticoid mediated signaling pathway|up-regulation of glucocorticoid mediated signaling pathway|activation of glucocorticoid mediated signalling|upregulation of glucocorticoid mediated signaling pathway|up-regulation of glucocorticoid mediated signalling|up regulation of glucocorticoid mediated signalling|positive regulation of glucocorticoid mediated signalling|upregulation of glucocorticoid mediated signalling							hjd	2012-03-08T08:33:23Z					biological_process											owl:Class	
GO:0006729	biolink:NamedThing	tetrahydrobiopterin biosynthetic process	The chemical reactions and pathways resulting in the formation of tetrahydrobiopterin, the reduced form of biopterin (2-amino-4-hydroxy-6-(1,2-dihydroxypropyl)-pteridine). It functions as a hydroxylation coenzyme, e.g. in the conversion of phenylalanine to tyrosine.	tmpzr1t_l9r_go_relaxed.owl	tetrahydrobiopterin biosynthesis|tetrahydrobiopterin synthesis|tetrahydrobiopterin formation|tetrahydrobiopterin anabolism|5,6,7,8-tetrahydrobiopterin biosynthetic process													biological_process											owl:Class	
GO:0046146	biolink:NamedThing	tetrahydrobiopterin metabolic process	The chemical reactions and pathways involving tetrahydrobiopterin, the reduced form of biopterin (2-amino-4-hydroxy-6-(1,2-dihydroxypropyl)-pteridine). It functions as a hydroxylation coenzyme, e.g. in the conversion of phenylalanine to tyrosine.	tmpzr1t_l9r_go_relaxed.owl	5,6,7,8-tetrahydrobiopterin metabolic process|tetrahydrobiopterin metabolism													biological_process											owl:Class	
GO:0032708	biolink:NamedThing	negative regulation of interleukin-24 production	Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-24 production.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of interleukin-24 biosynthetic process|downregulation of interleukin-24 production|down regulation of interleukin-24 production|negative regulation of IL-24 production|down-regulation of interleukin-24 production|inhibition of interleukin-24 production											GO:0045532		biological_process											owl:Class	
GO:0032668	biolink:NamedThing	regulation of interleukin-24 production	Any process that modulates the frequency, rate, or extent of interleukin-24 production.	tmpzr1t_l9r_go_relaxed.owl	regulation of IL-24 production|regulation of interleukin-24 biosynthetic process											GO:0045528		biological_process											owl:Class	
GO:0018876	biolink:NamedThing	benzonitrile metabolic process	The chemical reactions and pathways involving benzonitrile. Benzonitrile is used as a solvent and chemical intermediate in the pharmaceutical, dyestuffs and rubber industries. It is highly toxic and harmful in contact with skin.	tmpzr1t_l9r_go_relaxed.owl	benzonitrile metabolism				UM-BBD_pathwayID:bzn									biological_process											owl:Class	
GO:0033337	biolink:NamedThing	dorsal fin development	The process whose specific outcome is the progression of the dorsal fin over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0036325	biolink:NamedThing	vascular endothelial growth factor receptor-3 signaling pathway	Any series of molecular signals initiated by the binding of an extracellular ligand to a vascular endothelial growth factor receptor-3 (VEGFR-3) located on the surface of the receiving cell, and ending with regulation of a downstream cellular process, e.g. transcription.	tmpzr1t_l9r_go_relaxed.owl	VEGFR-3 signaling pathway|FLT4 signaling pathway|VEGFR3 signaling pathway							bf	2012-09-04T15:25:13Z					biological_process											owl:Class	
GO:0032847	biolink:NamedThing	regulation of cellular pH reduction	Any process that modulates the frequency, rate, or extent of a process that reduces the internal pH of a cell.	tmpzr1t_l9r_go_relaxed.owl	regulation of cell pH reduction|regulation of intracellular acidification|regulation of reduction of cellular pH|regulation of reduction of pH in cell|regulation of cellular acidification|regulation of intracellular pH reduction													biological_process											owl:Class	
GO:0051453	biolink:NamedThing	regulation of intracellular pH	Any process that modulates the internal pH of a cell, measured by the concentration of the hydrogen ion.	tmpzr1t_l9r_go_relaxed.owl	cellular pH regulation|regulation of cell pH|pH regulation in cell|cell pH regulation													biological_process											owl:Class	
GO:0043607	biolink:NamedThing	formamide biosynthetic process	The chemical reactions and pathways resulting in the formation of formamide, the simplest amide, HCONH2, derived from formic acid.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0036496	biolink:NamedThing	regulation of translational initiation by eIF2 alpha dephosphorylation	Any process that modulates the frequency, rate or extent of translation initiation in response to stress by the dephosphorylation of eIF2 alpha.	tmpzr1t_l9r_go_relaxed.owl								bf	2015-02-05T10:21:31Z					biological_process											owl:Class	
GO:0072756	biolink:NamedThing	cellular response to paraquat	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a paraquat stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2012-11-07T12:08:59Z					biological_process											owl:Class	
GO:1901562	biolink:NamedThing	response to paraquat	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a paraquat stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2012-11-02T15:32:41Z					biological_process											owl:Class	
GO:0090679	biolink:NamedThing	cell differentiation involved in phenotypic switching	A cell differentiation process that is a part of a reversible switch of a cell from one cell type or form to another, at a frequency above the expected frequency for somatic mutations.	tmpzr1t_l9r_go_relaxed.owl								tb	2016-04-28T17:32:40Z					biological_process											owl:Class	
GO:0034703	biolink:NamedThing	cation channel complex	An ion channel complex through which cations pass.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0020014	biolink:NamedThing	schizogony	Cell division by multiple fission in which nuclei and other organelles in the parent cell divide repeatedly and move to the cell periphery before internal membranes develop around them, producing a large number of daughter cells simultaneously.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Protozoal_merogony									biological_process											owl:Class	
GO:0015288	biolink:NamedThing	porin activity	Enables the transfer of substances, sized less than 1000 Da, from one side of a membrane to the other. The transmembrane portions of porins consist exclusively of beta-strands which form a beta-barrel. They are found in the outer membranes of Gram-negative bacteria, mitochondria, plastids and possibly acid-fast Gram-positive bacteria.	tmpzr1t_l9r_go_relaxed.owl	porin|outer membrane exporter porin				Wikipedia:Porin_(protein)									molecular_function											owl:Class	
GO:0022829	biolink:NamedThing	wide pore channel activity	Enables the transport of a solute across a membrane via a large pore, un-gated channel. Examples include gap junctions, which transport substances from one cell to another; and porins which transport substances in and out of bacteria, mitochondria and chloroplasts.	tmpzr1t_l9r_go_relaxed.owl	gap junction activity|non-gated, wide pore channel activity													molecular_function											owl:Class	
GO:0048635	biolink:NamedThing	negative regulation of muscle organ development	Any process that stops, prevents, or reduces the frequency, rate or extent of muscle development.	tmpzr1t_l9r_go_relaxed.owl	down regulation of muscle development|downregulation of muscle development|down-regulation of muscle development|inhibition of muscle development													biological_process											owl:Class	
GO:0061367	biolink:NamedThing	behavioral response to acetic acid induced pain	Any process that results in a change in the behaviour of an organism as a result of an acetic acid pain stimulus.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-10-21T03:26:31Z					biological_process											owl:Class	
GO:1990103	biolink:NamedThing	DnaA-HU complex	A protein-DNA complex containing DNA-bound DnaA attached to HU. HU is a dimer encoded by two closely related genes. Essential for the initiation of replication in bacteria; stimulates the DnaA-dependent unwinding of oriC.	tmpzr1t_l9r_go_relaxed.owl	DnaA-HU-DNA complex							bhm	2013-05-14T12:36:39Z					cellular_component											owl:Class	
GO:1990077	biolink:NamedThing	primosome complex	Any of a family of protein complexes that form at the origin of replication or stalled replication forks and function in replication primer synthesis in all organisms.  Early complexes initiate double-stranded DNA unwinding. The core unit consists of a replicative helicase and a primase. The helicase further unwinds the DNA and recruits the polymerase machinery. The primase synthesizes RNA primers that act as templates for complementary stand replication by the polymerase machinery. The primosome contains a number of associated proteins and protein complexes and contributes to the processes of replication initiation, lagging strand elongation, and replication restart.	tmpzr1t_l9r_go_relaxed.owl	primosome							bhm	2013-04-26T11:55:28Z					cellular_component											owl:Class	
GO:0071930	biolink:NamedThing	negative regulation of transcription involved in G1/S transition of mitotic cell cycle	Any process that stop, prevents or decreases transcription as part of the G1/S transition of the mitotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of transcription from RNA polymerase II promoter involved in G1/S transition of mitotic cell cycle|negative regulation of transcription from RNA polymerase II promoter during G1/S phase of mitotic cell cycle							mah	2010-09-29T11:12:11Z					biological_process											owl:Class	
GO:0000083	biolink:NamedThing	regulation of transcription involved in G1/S transition of mitotic cell cycle	Any process that regulates transcription such that the target genes are involved in the transition between G1 and S phase of the mitotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0016156	biolink:NamedThing	fumarate reductase (NADH) activity	Catalysis of the reaction: NAD(+) + succinate = fumarate + H(+) + NADH.	tmpzr1t_l9r_go_relaxed.owl	succinate:NAD+ oxidoreductase activity|NADH-dependent fumarate reductase activity|NADH-fumarate reductase activity				EC:1.3.1.6|KEGG_REACTION:R00402|RHEA:18281|MetaCyc:FUMARATE-REDUCTASE-NADH-RXN									molecular_function											owl:Class	
GO:0033415	biolink:NamedThing	UGA codon-amino acid adaptor activity	A triplet codon-amino acid adaptor activity that recognizes a UGA codon.	tmpzr1t_l9r_go_relaxed.owl	TGA codon-amino acid adaptor activity					Note that in the standard genetic code, TGA is a stop codon (opal) and is not normally read by a tRNA.								molecular_function											owl:Class	
GO:0033061	biolink:NamedThing	DNA recombinase mediator complex	A protein complex containing accessory proteins which bind a recombinase (e.g. Rad51) and bind single-stranded DNA (ssDNA), and promote nucleation of the recombinase onto ssDNA through facilitating recombinase-RPA exchange.	tmpzr1t_l9r_go_relaxed.owl						Many paralogs of Rad51 act as recombinase mediators. These paralogs dimerize (or occasionally form tetramers) amongst themselves to form complexes with ssDNA-binding activity, and which act as mediators of Rad51 presynaptic filament assembly.								cellular_component											owl:Class	
GO:0021988	biolink:NamedThing	olfactory lobe development	The progression of the olfactory lobe over time from its initial formation until its mature state. The olfactory lobe is the area of the brain that process the neural inputs for the sense of smell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1990023	biolink:NamedThing	mitotic spindle midzone	The area in the center of the anaphase spindle consisting of microtubules, microtubule bundling factors and kinesin motors where the spindle microtubules from opposite poles overlap in an antiparallel manner.	tmpzr1t_l9r_go_relaxed.owl								vw	2013-02-05T15:41:48Z					cellular_component											owl:Class	
GO:0051233	biolink:NamedThing	spindle midzone	The area in the center of the spindle where the spindle microtubules from opposite poles overlap.	tmpzr1t_l9r_go_relaxed.owl	spindle equator|central spindle													cellular_component											owl:Class	
GO:0071258	biolink:NamedThing	cellular response to gravity	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gravitational stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to gravitational stimulus							mah	2009-12-04T03:31:36Z					biological_process											owl:Class	
GO:0004339	biolink:NamedThing	glucan 1,4-alpha-glucosidase activity	Catalysis of the hydrolysis of terminal (1->4)-linked alpha-D-glucose residues successively from non-reducing ends of the chains with release of beta-D-glucose.	tmpzr1t_l9r_go_relaxed.owl	exo-1,4-alpha-glucosidase activity|amyloglucosidase activity|1,4-alpha-D-glucan glucohydrolase activity|glucoamylase activity|gamma-1,4-glucan glucohydrolase activity|lysosomal alpha-glucosidase activity|glucose amylase activity|gamma-amylase activity				EC:3.2.1.3|MetaCyc:3.2.1.3-RXN	Note that this term is not a child of 'alpha-glucosidase activity ; GO:0090599', because in the reaction represented by GO:0004339 results in the release of beta-D-glucose, whereas in GO:0090599 alpha-D-glucose is released.								molecular_function											owl:Class	
GO:0086074	biolink:NamedThing	Purkinje myocyte-ventricular cardiac muscle cell adhesion involved in cell communication	The attachment of an Purkinje myocyte to a ventricular cardiac muscle cell via adhesion molecules that results in the cells being juxtaposed so that they can communicate.	tmpzr1t_l9r_go_relaxed.owl								dph	2011-11-22T10:02:24Z					biological_process											owl:Class	
GO:0035175	biolink:NamedThing	histone kinase activity (H3-S10 specific)	Catalysis of the transfer of a phosphate group to the serine-10 residue of the N-terminal tail of histone H3.	tmpzr1t_l9r_go_relaxed.owl	histone serine kinase activity (H3-S10 specific)|histone kinase activity (H3-S3 specific)|histone-serine kinase activity (H3-S10 specific)											GO:0044021		molecular_function											owl:Class	
GO:1902976	biolink:NamedThing	premeiotic DNA replication preinitiation complex assembly	Any DNA replication preinitiation complex assembly that is involved in meiotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl	pre-IC complex assembly involved in meiotic cell cycle|DNA replication preinitiation complex formation involved in meiotic cell cycle							jl	2014-05-06T19:19:31Z					biological_process											owl:Class	
GO:1901649	biolink:NamedThing	negative regulation of actomyosin contractile ring localization	Any process that stops, prevents or reduces the frequency, rate or extent of actomyosin contractile ring localization.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of contractile ring localization involved in cell cycle cytokinesis|inhibition of actomyosin contractile ring localization|inhibition of contractile ring localization involved in cell cycle cytokinesis|negative regulation of contractile ring localization involved in cell cycle cytokinesis|negative regulation of contractile ring localisation involved in cell cycle cytokinesis|down-regulation of contractile ring localisation involved in cell cycle cytokinesis|inhibition of contractile ring localisation involved in cell cycle cytokinesis|downregulation of contractile ring localization involved in cell cycle cytokinesis|downregulation of contractile ring localisation involved in cell cycle cytokinesis|downregulation of actomyosin contractile ring localization|down regulation of contractile ring localisation involved in cell cycle cytokinesis|down-regulation of actomyosin contractile ring localization|down regulation of contractile ring localization involved in cell cycle cytokinesis|down regulation of actomyosin contractile ring localization							vw	2012-11-19T13:42:49Z					biological_process											owl:Class	
GO:0010725	biolink:NamedThing	regulation of primitive erythrocyte differentiation	Any process that modulates the rate, frequency, or extent of primitive erythrocyte differentiation. Primitive erythrocyte differentiation occurs as part of the process of primitive hemopoiesis.	tmpzr1t_l9r_go_relaxed.owl	regulation of primitive erythropoeisis|regulation of primitive red blood cell differentiation|regulation of primitive RBC differentiation													biological_process											owl:Class	
GO:0080192	biolink:NamedThing	primary thickening	Lateral growth of a plant axis (shoot axis or root) that is an increase in thickness resulting from the activity of a primary thickening meristem.	tmpzr1t_l9r_go_relaxed.owl						Occurs in shoot axes and rarely in roots in many monocotyledons.		dhl	2012-12-06T15:55:18Z					biological_process											owl:Class	
GO:0039574	biolink:NamedThing	suppression by virus of host JAK-STAT cascade via inhibition of host TYK2 activity	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of a JAK1-STAT signaling cascade in a host organism by reducing the activity of host TYK2 (tyrosine kinase 2). TYK2 is an intracellular signal-transducing tyrosine kinase that associates with the cytoplasmic tails of cytokine receptors and transmits the cytokine signal by phosphorylating receptor subunits.	tmpzr1t_l9r_go_relaxed.owl	suppression by virus of host TYK2 activity|suppression by virus of host non-receptor tyrosine-protein kinase TYK2 activity	https://github.com/geneontology/go-ontology/issues/21986						bf						biological_process											owl:Class	
GO:0140720	biolink:NamedThing	subtelomeric heterochromatin	Heterochromatin that is located adjacent to the telomere, and characterized by methylated H3 histone at lysine 9 (H3K9me2/H3K9me3).	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/22353						pg	2021-11-05T13:19:40Z					cellular_component											owl:Class	
GO:0034316	biolink:NamedThing	negative regulation of Arp2/3 complex-mediated actin nucleation	Any process that stops, prevents, or reduces the frequency, rate or extent of actin nucleation mediated by the Arp2/3 complex and interacting proteins.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1904434	biolink:NamedThing	positive regulation of ferrous iron binding	Any process that activates or increases the frequency, rate or extent of ferrous iron binding.	tmpzr1t_l9r_go_relaxed.owl	activation of ferrous iron binding|up regulation of ferrous iron binding|up-regulation of ferrous iron binding|upregulation of ferrous iron binding							kom	2015-07-06T13:46:42Z					biological_process											owl:Class	
GO:1901425	biolink:NamedThing	response to formic acid	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a formic acid stimulus.	tmpzr1t_l9r_go_relaxed.owl								tt	2012-10-01T18:43:05Z					biological_process											owl:Class	
GO:0002573	biolink:NamedThing	myeloid leukocyte differentiation	The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of any cell of the myeloid leukocyte lineage.	tmpzr1t_l9r_go_relaxed.owl	myeloid leucocyte differentiation													biological_process											owl:Class	
GO:0003934	biolink:NamedThing	GTP cyclohydrolase I activity	Catalysis of the reaction: GTP + H2O = formate + 7,8-dihydroneopterin 3'-triphosphate.	tmpzr1t_l9r_go_relaxed.owl	GTP 7,8-8,9-dihydrolase activity|dihydroneopterin triphosphate synthase activity|guanosine triphosphate cyclohydrolase activity|guanosine triphosphate 8-deformylase activity|GTP 8-formylhydrolase activity				EC:3.5.4.16|Reactome:R-HSA-1474146|RHEA:17473|MetaCyc:GTP-CYCLOHYDRO-I-RXN|KEGG_REACTION:R00424									molecular_function											owl:Class	
GO:0003933	biolink:NamedThing	GTP cyclohydrolase activity	Catalysis of the hydrolysis of the imidazole ring of GTP, releasing formate. Two C-N bonds are hydrolyzed and the pentase unit is isomerized.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0045654	biolink:NamedThing	positive regulation of megakaryocyte differentiation	Any process that activates or increases the frequency, rate or extent of megakaryocyte differentiation.	tmpzr1t_l9r_go_relaxed.owl	up regulation of megakaryocyte differentiation|activation of megakaryocyte differentiation|upregulation of megakaryocyte differentiation|stimulation of megakaryocyte differentiation|up-regulation of megakaryocyte differentiation													biological_process											owl:Class	
GO:1990696	biolink:NamedThing	USH2 complex	A protein complex composed of four proteins, loss of which results in Usher Syndrome type 2 (USH2 syndrome), a leading genetic cause of combined hearing and vision loss. This complex is conserved in many species; in mice, it is composed of USH2A, GPR98 (aka ADGRV1), WHRN, and PDZD7.	tmpzr1t_l9r_go_relaxed.owl	USH2 quaternary protein complex							krc	2015-03-12T17:29:18Z					cellular_component											owl:Class	
GO:0031291	biolink:NamedThing	Ran protein signal transduction	A series of molecular signals within the cell that are mediated by a member of the Ran family of proteins switching to a GTP-bound active state.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1902913	biolink:NamedThing	positive regulation of neuroepithelial cell differentiation	Any process that activates or increases the frequency, rate or extent of neuroepithelial cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	upregulation of neuroepithelial cell differentiation|up regulation of neuroepithelial cell differentiation|activation of neuroepithelial cell differentiation|up-regulation of neuroepithelial cell differentiation							mr	2014-04-18T21:06:42Z					biological_process											owl:Class	
GO:0004126	biolink:NamedThing	cytidine deaminase activity	Catalysis of the reaction: cytidine + H2O = uridine + NH3.	tmpzr1t_l9r_go_relaxed.owl	cytosine nucleoside deaminase activity|cytidine aminohydrolase activity				Reactome:R-HSA-73608|Reactome:R-HSA-83677|RHEA:16069|EC:3.5.4.5|MetaCyc:CYTIDEAM2-RXN									molecular_function											owl:Class	
GO:0002059	biolink:NamedThing	thymine binding	Binding to thymine.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0002061	biolink:NamedThing	pyrimidine nucleobase binding	Binding to a pyrimidine nucleobase, an organic nitrogenous base with a pyrimidine skeleton.	tmpzr1t_l9r_go_relaxed.owl	1,3-diazine binding|pyrimidine binding|pyrimidine base binding													molecular_function											owl:Class	
GO:0051327	biolink:NamedThing	meiotic M phase	A cell cycle phase during which nuclear division occurs, and which is comprises the phases: prophase, metaphase, anaphase and telophase and occurs as part of a meiotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl	M phase of meiotic cell cycle					Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).								biological_process											owl:Class	
GO:1904751	biolink:NamedThing	positive regulation of protein localization to nucleolus	Any process that activates or increases the frequency, rate or extent of protein localization to nucleolus.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of protein localization in nucleolus|up-regulation of protein localization to nucleolus|up-regulation of protein localisation in nucleolus|upregulation of protein localization in nucleolus|up regulation of protein localisation to nucleolus|activation of protein localisation to nucleolus|upregulation of protein localisation to nucleolus|activation of protein localization in nucleolus|up-regulation of protein localisation to nucleolus|upregulation of protein localisation in nucleolus|up regulation of protein localisation in nucleolus|up-regulation of protein localization in nucleolus|up regulation of protein localization to nucleolus|up regulation of protein localization in nucleolus|positive regulation of protein localisation in nucleolus|activation of protein localization to nucleolus|activation of protein localisation in nucleolus|upregulation of protein localization to nucleolus|positive regulation of protein localisation to nucleolus							nc	2015-10-19T15:16:30Z					biological_process											owl:Class	
GO:0000242	biolink:NamedThing	pericentriolar material	A network of small fibers that surrounds the centrioles in cells; contains the microtubule nucleating activity of the centrosome.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:1903799	biolink:NamedThing	negative regulation of production of miRNAs involved in gene silencing by miRNA	Any process that stops, prevents or reduces the frequency, rate or extent of production of miRNAs involved in gene silencing by miRNA.	tmpzr1t_l9r_go_relaxed.owl	downregulation of miRNA-mediated gene silencing, production of miRNAs|negative regulation of microRNA biosynthesis|negative regulation of miRNA biogenesis|inhibition of gene silencing by miRNA, production of miRNAs|inhibition of microRNA biosynthetic process|negative regulation of production of microRNAs involved in gene silencing by microRNA|downregulation of miRNA biogenesis|negative regulation of miRNA processing|negative regulation of microRNA-mediated gene silencing, production of microRNAs|downregulation of microRNA metabolic process|downregulation of microRNA biosynthetic process|negative regulation of microRNA metabolism|down regulation of microRNA biosynthetic process|down-regulation of miRNA processing|inhibition of microRNA metabolism|down-regulation of miRNA biogenesis|down-regulation of production of miRNAs involved in gene silencing by miRNA|negative regulation of microRNA biogenesis|down-regulation of microRNA metabolism|down regulation of microRNA biosynthesis|inhibition of miRNA biogenesis|down-regulation of miRNA-mediated gene silencing, production of miRNAs|downregulation of gene silencing by miRNA, production of miRNAs|down-regulation of gene silencing by miRNA, production of miRNAs|inhibition of microRNA metabolic process|negative regulation of miRNA-mediated gene silencing, production of miRNAs|inhibition of miRNA processing|down-regulation of microRNA biosynthetic process|downregulation of microRNA-mediated gene silencing, production of microRNAs|down-regulation of microRNA-mediated gene silencing, production of microRNAs|downregulation of production of microRNAs involved in gene silencing by microRNA|down regulation of production of microRNAs involved in gene silencing by microRNA|down regulation of microRNA-mediated gene silencing, production of microRNAs|negative regulation of gene silencing by miRNA, production of miRNAs|down regulation of gene silencing by miRNA, production of miRNAs|inhibition of microRNA biosynthesis|downregulation of microRNA biosynthesis|down-regulation of microRNA biosynthesis|down-regulation of microRNA metabolic process|down regulation of miRNA biogenesis|down regulation of miRNA processing|negative regulation of microRNA metabolic process|down regulation of microRNA biogenesis|down-regulation of production of microRNAs involved in gene silencing by microRNA|down-regulation of microRNA biogenesis|inhibition of miRNA-mediated gene silencing, production of miRNAs|down regulation of production of miRNAs involved in gene silencing by miRNA|downregulation of microRNA metabolism|downregulation of miRNA processing|inhibition of production of miRNAs involved in gene silencing by miRNA|negative regulation of microRNA biosynthetic process|down regulation of microRNA metabolism|inhibition of microRNA-mediated gene silencing, production of microRNAs|inhibition of microRNA biogenesis|downregulation of microRNA biogenesis|inhibition of production of microRNAs involved in gene silencing by microRNA|down regulation of microRNA metabolic process|down regulation of miRNA-mediated gene silencing, production of miRNAs|downregulation of production of miRNAs involved in gene silencing by miRNA							rph	2015-01-15T13:58:22Z					biological_process											owl:Class	
GO:1903798	biolink:NamedThing	regulation of production of miRNAs involved in gene silencing by miRNA	Any process that modulates the frequency, rate or extent of production of miRNAs involved in gene silencing by miRNA.	tmpzr1t_l9r_go_relaxed.owl	regulation of microRNA processing|regulation of miRNA biogenesis|regulation of miRNA-mediated gene silencing, production of miRNAs|regulation of microRNA biogenesis|regulation of microRNA metabolism|regulation of microRNA metabolic process|regulation of gene silencing by miRNA, production of miRNAs|regulation of microRNA biosynthetic process|regulation of microRNA-mediated gene silencing, production of microRNAs|regulation of production of microRNAs involved in gene silencing by microRNA|regulation of microRNA biosynthesis|regulation of miRNA processing							rph	2015-01-15T13:58:12Z					biological_process											owl:Class	
GO:0007505	biolink:NamedThing	adult fat body development	The process whose specific outcome is the progression of the adult fat body over time, from its formation to the mature structure. Larval fat body cells that remain at eclosion degenerate in the first 2 to 4 days of adult life, leaving behind the smaller cells of the adult fat body.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0106163	biolink:NamedThing	regulation of exonucleolytic catabolism of deadenylated mRNA	Any process that modulates the frequency, rate or extent of exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay.	tmpzr1t_l9r_go_relaxed.owl								hjd	2019-01-15T15:33:08Z					biological_process											owl:Class	
GO:0035241	biolink:NamedThing	protein-arginine omega-N monomethyltransferase activity	Catalysis of the addition of a methyl group to either of the unmethylated terminal nitrogen atoms (also called omega nitrogen) in peptidyl-arginine to form an omega-N-G-monomethylated arginine residue.  The reaction is S-adenosyl-L-methionine + [protein]-L-arginine = S-adenosyl-L-homocysteine + [protein]-Nomega-methyl-L-arginine.	tmpzr1t_l9r_go_relaxed.owl	type III protein arginine methyltransferase activity|S-adenosyl-L-methionine:[protein]-L-arginine N-methyltransferase ([protein]-Nomega-methyl-L-arginine-forming)				EC:2.1.1.321|RHEA:48100|RESID:AA0069	Type III protein arginine methyltransferases catalyze the single methylation of one of the terminal nitrogen atoms of the guanidino group in an L-arginine residue within a protein. Unlike type I and type II protein arginine methyltransferases, which also catalyze this reaction, type III enzymes do not methylate the substrate any further.								molecular_function											owl:Class	
GO:0062171	biolink:NamedThing	lutein biosynthetic process	The chemical reactions and pathways resulting in the formation of lutein.	tmpzr1t_l9r_go_relaxed.owl	lutein formation|lutein anabolism|lutein biosynthesis							dph	2019-11-18T16:01:00Z					biological_process											owl:Class	
GO:0071126	biolink:NamedThing	alphaV-beta6 integrin-osteopontin complex	A protein complex that consists of an alphaV-beta6 integrin complex bound to osteopontin.	tmpzr1t_l9r_go_relaxed.owl	ITGAV-ITGB6-SPP1 complex							mah	2009-11-13T02:23:43Z					cellular_component											owl:Class	
GO:1900266	biolink:NamedThing	negative regulation of substance P receptor binding	Any process that stops, prevents or reduces the frequency, rate or extent of substance P receptor binding.	tmpzr1t_l9r_go_relaxed.owl	downregulation of neurokinin-1 receptor binding|inhibition of substance P receptor binding|downregulation of substance P receptor binding|negative regulation of neurokinin-1 receptor binding|inhibition of neurokinin-1 receptor binding|down regulation of substance P receptor binding|downregulation of substance P receptor ligand|down-regulation of substance P receptor ligand|down regulation of neurokinin-1 receptor binding|down regulation of substance P receptor ligand|inhibition of substance P receptor ligand|negative regulation of substance P receptor ligand|down-regulation of substance P receptor binding|down-regulation of neurokinin-1 receptor binding							tb	2012-04-03T11:11:36Z					biological_process											owl:Class	
GO:0032364	biolink:NamedThing	oxygen homeostasis	A homeostatic process involved in the maintenance of an internal steady state of oxygen within an organism or cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0033483	biolink:NamedThing	gas homeostasis	A homeostatic process involved in the maintenance of an internal steady state of a gas within an organism or cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1905469	biolink:NamedThing	negative regulation of clathrin-coated pit assembly	Any process that stops, prevents or reduces the frequency, rate or extent of clathrin-coated pit assembly.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of coated pit assembly|inhibition of coated pit formation|down-regulation of clathrin-coated pit assembly|downregulation of coated pit formation|inhibition of clathrin-coated pit assembly|down regulation of coated pit formation|inhibition of coated pit assembly|negative regulation of clathrin-coated pit formation|negative regulation of coated pit formation|down-regulation of coated pit formation|negative regulation of coated pit assembly|down regulation of coated pit assembly|inhibition of clathrin-coated pit formation|downregulation of coated pit assembly|down regulation of clathrin-coated pit formation|downregulation of clathrin-coated pit formation|down regulation of clathrin-coated pit assembly|downregulation of clathrin-coated pit assembly|down-regulation of clathrin-coated pit formation							bf	2016-09-20T10:04:45Z					biological_process											owl:Class	
GO:0006649	biolink:NamedThing	phospholipid transfer to membrane	The transfer of a phospholipid from its site of synthesis to the plasma membrane.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0035719	biolink:NamedThing	tRNA import into nucleus	The directed movement of tRNA from the cytoplasm to the nucleus.	tmpzr1t_l9r_go_relaxed.owl	retrograde tRNA transport into nucleus|tRNA nuclear import							bf	2011-03-03T04:32:35Z					biological_process											owl:Class	
GO:0033924	biolink:NamedThing	dextran 1,6-alpha-isomaltotriosidase activity	Catalysis of the hydrolysis of (1->6)-alpha-D-glucosidic linkages in dextrans, to remove successive isomaltotriose units from the non-reducing ends of the chains.	tmpzr1t_l9r_go_relaxed.owl	1,6-alpha-D-glucan isomaltotriohydrolase activity|exo-isomaltotriohydrolase activity				MetaCyc:3.2.1.95-RXN|EC:3.2.1.95									molecular_function											owl:Class	
GO:0098541	biolink:NamedThing	cytoplasmic side of trans-Golgi network transport vesicle membrane	The side (leaflet) of the trans-Golgi network transport vesicle membrane that faces the cytoplasm.	tmpzr1t_l9r_go_relaxed.owl	external side of trans-Golgi network transport vesicle membrane							dos	2013-10-24T11:56:30Z					cellular_component											owl:Class	
GO:0033875	biolink:NamedThing	ribonucleoside bisphosphate metabolic process	The chemical reactions and pathways involving a ribonucleoside bisphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar.	tmpzr1t_l9r_go_relaxed.owl	ribonucleoside bisphosphate metabolism													biological_process											owl:Class	
GO:0106093	biolink:NamedThing	EDS1 disease-resistance complex	A plant complex involved in basal disease resistance and resistance (R) gene-mediated effector triggered immunity (ETI). Regulates accumulation of the hormone salicylic acid (SA) which is a necessary component of systemic immunity. Involved in responds to bacteria, viruses and oomycetes.	tmpzr1t_l9r_go_relaxed.owl	EDS1-PAD4 complex|EDS1-PAD4-SAG101 complex|EDS1-SAG101 complex					Interacts with the R genes triggering ETI and systemic resistance.		hjd	2018-01-29T20:02:47Z					cellular_component											owl:Class	
GO:0102962	biolink:NamedThing	4,4'-diapo-zeta-carotene desaturase activity	Catalysis of the reaction: all-trans-4,4'-diapo-zeta-carotene + FAD + H+ = 4,4'-diaponeurosporene + FADH2.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-9305|RHEA:31403									molecular_function											owl:Class	
GO:1904206	biolink:NamedThing	positive regulation of skeletal muscle hypertrophy	Any process that activates or increases the frequency, rate or extent of skeletal muscle hypertrophy.	tmpzr1t_l9r_go_relaxed.owl	activation of skeletal muscle hypertrophy|up-regulation of skeletal muscle hypertrophy|up regulation of skeletal muscle hypertrophy|upregulation of skeletal muscle hypertrophy							sl	2015-05-08T17:38:25Z					biological_process											owl:Class	
GO:0071604	biolink:NamedThing	transforming growth factor beta production	The appearance of any member of the transforming growth factor-beta family of cytokines due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Transforming growth factor-beta family members include TGF-B1, TGF-B2, and TGF-B3.	tmpzr1t_l9r_go_relaxed.owl	TGFb production|TGFbeta production|transforming growth factor-beta secretion|TGF-B production|transforming growth factor-beta production|TGF-beta production							mah	2010-02-05T03:56:57Z			GO:0038044		biological_process											owl:Class	
GO:0090314	biolink:NamedThing	positive regulation of protein targeting to membrane	Any process that increases the frequency, rate or extent of the process of directing proteins towards a membrane, usually using signals contained within the protein.	tmpzr1t_l9r_go_relaxed.owl								tb	2010-04-16T03:42:22Z					biological_process											owl:Class	
GO:0032841	biolink:NamedThing	calcitonin binding	Binding to calcitonin, a peptide hormone responsible for reducing serum calcium levels by inhibiting osteoclastic bone reabsorption and promoting renal calcium excretion. It is synthesized and released by the C cells of the thyroid.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1990831	biolink:NamedThing	cellular response to carcinoembryonic antigen	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carcinoembryonic antigen stimulus. The carcinoembryonic antigens represent a family of glycoproteins.	tmpzr1t_l9r_go_relaxed.owl	cellular response to pregnancy specific glycoprotein							sl	2015-08-20T19:43:12Z					biological_process											owl:Class	
GO:0099013	biolink:NamedThing	neuronal dense core vesicle lumen	The volume enclosed by a neuronal dense core vesicle membrane.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0002427	biolink:NamedThing	mucosal tolerance induction	Tolerance induction taking place in the mucosal tissues.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0002462	biolink:NamedThing	tolerance induction to nonself antigen	Tolerance induction in response to nonself antigens.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0110139	biolink:NamedThing	negative regulation of imaginal disc-derived leg joint morphogenesis	Any process that stops, prevents, or reduces the frequency, rate or extent of imaginal disc-derived leg joint morphogenesis.	tmpzr1t_l9r_go_relaxed.owl								kmv	2019-02-12T15:40:09Z					biological_process											owl:Class	
GO:1900154	biolink:NamedThing	regulation of bone trabecula formation	Any process that modulates the frequency, rate or extent of bone trabecula formation.	tmpzr1t_l9r_go_relaxed.owl	regulation of skeletal trabeculation|regulation of bone trabeculation|regulation of skeletal trabecula biogenesis|regulation of skeletal trabecula formation|regulation of bone trabecula biogenesis							vk	2012-03-07T01:47:03Z					biological_process											owl:Class	
GO:0047699	biolink:NamedThing	beta-diketone hydrolase activity	Catalysis of the reaction: H(2)O + nonane-4,6-dione = butanoate + H(+) + pentan-2-one.	tmpzr1t_l9r_go_relaxed.owl	b-diketone hydrolase activity|oxidized PVA hydrolase activity|nonane-4,6-dione acylhydrolase activity				EC:3.7.1.7|RHEA:11908|MetaCyc:BETA-DIKETONE-HYDROLASE-RXN|KEGG_REACTION:R03781									molecular_function											owl:Class	
GO:0015400	biolink:NamedThing	low-affinity secondary active ammonium transmembrane transporter activity	Enables the transfer of ammonium from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters. In low-affinity transport the transporter is able to bind the solute only if it is present at very high concentrations.	tmpzr1t_l9r_go_relaxed.owl	low affinity ammonium transmembrane transporter activity|low affinity secondary active ammonium transmembrane transporter activity													molecular_function											owl:Class	
GO:0034937	biolink:NamedThing	perchlorate reductase activity	Catalysis of the reaction: perchlorate + 2 H+ + 2 e- = chlorate + H2O.	tmpzr1t_l9r_go_relaxed.owl					EC:1.97.1.-|UM-BBD_reactionID:r0980									molecular_function											owl:Class	
GO:0033865	biolink:NamedThing	nucleoside bisphosphate metabolic process	The chemical reactions and pathways involving a nucleoside bisphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar.	tmpzr1t_l9r_go_relaxed.owl	nucleoside bisphosphate metabolism													biological_process											owl:Class	
GO:0034605	biolink:NamedThing	cellular response to heat	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.	tmpzr1t_l9r_go_relaxed.owl	cellular response to heat stress													biological_process											owl:Class	
GO:1904335	biolink:NamedThing	regulation of ductus arteriosus closure	Any process that modulates the frequency, rate or extent of ductus arteriosus closure.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-06-11T17:45:15Z					biological_process											owl:Class	
GO:0014019	biolink:NamedThing	neuroblast development	The process aimed at the progression of a neuroblast over time, from initial commitment of the cell to a specific state, to the mature neuroblast. It does not include processes where the neuroblast turns into a glial cell or a neuron.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0015934	biolink:NamedThing	large ribosomal subunit	The larger of the two subunits of a ribosome. Two sites on the ribosomal large subunit are involved in translation, namely the aminoacyl site (A site) and peptidyl site (P site).	tmpzr1t_l9r_go_relaxed.owl	ribosomal large subunit													cellular_component											owl:Class	
GO:0044391	biolink:NamedThing	ribosomal subunit	Either of the two subunits of a ribosome: the ribosomal large subunit or the ribosomal small subunit.	tmpzr1t_l9r_go_relaxed.owl								jl	2011-12-15T04:47:59Z					cellular_component											owl:Class	
GO:0031536	biolink:NamedThing	positive regulation of exit from mitosis	Any process that activates or increases the rate of progression from anaphase/telophase (high mitotic CDK activity) to G1 (low mitotic CDK activity).	tmpzr1t_l9r_go_relaxed.owl	stimulation of exit from mitosis|up regulation of exit from mitosis|activation of exit from mitosis|up-regulation of exit from mitosis|upregulation of exit from mitosis													biological_process											owl:Class	
GO:1901992	biolink:NamedThing	positive regulation of mitotic cell cycle phase transition	Any process that activates or increases the frequency, rate or extent of mitotic cell cycle phase transition.	tmpzr1t_l9r_go_relaxed.owl	upregulation of mitotic cell cycle phase transition|up-regulation of mitotic cell cycle phase transition|up regulation of mitotic cell cycle phase transition|activation of mitotic cell cycle phase transition							jl	2013-03-19T16:14:51Z					biological_process											owl:Class	
GO:1901133	biolink:NamedThing	kanamycin biosynthetic process	The chemical reactions and pathways resulting in the formation of kanamycin.	tmpzr1t_l9r_go_relaxed.owl	kanamycin biosynthesis|kanamycin formation|kanamycin anabolism|kanamycin synthesis							yaf	2012-07-11T03:27:32Z					biological_process											owl:Class	
GO:0003355	biolink:NamedThing	cilium movement involved in otolith formation	The directed, self-propelled movement of cilia of inner ear epithelial cells, resulting the aggregation of otolith seed particles.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-12-03T10:21:08Z					biological_process											owl:Class	
GO:0050519	biolink:NamedThing	holo-citrate lyase synthase activity	Catalysis of the reaction: apo-citrate lyase + 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA = diphosphate + holo-citrate lyase.	tmpzr1t_l9r_go_relaxed.owl	holo-ACP synthase activity|2'-(5''-phosphoribosyl)-3'-dephospho-CoA transferase activity|CitX|2'-(5''-triphosphoribosyl)-3'-dephospho-CoA:apo-citrate lyase adenylyltransferase activity|2'-(5''-triphosphoribosyl)-3'-dephospho-CoA:apo-citrate lyase activity				EC:2.7.7.61|MetaCyc:2.7.7.61-RXN|RHEA:16333									molecular_function											owl:Class	
GO:0035679	biolink:NamedThing	anterior lateral line neuromast hair cell morphogenesis	The change in form (cell shape and size) that occurs when an anterior lateral line neuromast hair cell progresses from its initial formation to its mature state. A neuromast hair cell is a hair cell that acts as a sensory receptor of the neuromast; it is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-02-14T11:06:54Z					biological_process											owl:Class	
GO:0042984	biolink:NamedThing	regulation of amyloid precursor protein biosynthetic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of amyloid precursor protein (APP), the precursor of amyloid-beta.	tmpzr1t_l9r_go_relaxed.owl	regulation of amyloid precursor protein anabolism|regulation of APP biosynthesis|regulation of amyloid precursor protein synthesis|regulation of amyloid precursor protein formation|regulation of amyloid precursor protein biosynthesis|regulation of APP biosynthetic process													biological_process											owl:Class	
GO:0051618	biolink:NamedThing	positive regulation of histamine uptake	Any process that activates or increases the frequency, rate or extent of the directed movement of histamine into a cell.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of histamine uptake|stimulation of histamine uptake|up regulation of histamine uptake|activation of histamine uptake|upregulation of histamine uptake|positive regulation of histamine import													biological_process											owl:Class	
GO:0002325	biolink:NamedThing	natural killer cell differentiation involved in immune response	The process in which a naive natural killer cell acquires the specialized features of an effector natural killer T cell as part of an immune response.	tmpzr1t_l9r_go_relaxed.owl	natural killer cell development involved in immune response|natural killer cell differentiation during immune response|NK cell differentiation during immune response					Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.								biological_process											owl:Class	
GO:0001779	biolink:NamedThing	natural killer cell differentiation	The process in which a relatively unspecialized cell acquires the specialized features of a natural killer cell.	tmpzr1t_l9r_go_relaxed.owl	natural killer cell development|NK cell differentiation					Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.								biological_process											owl:Class	
GO:0002921	biolink:NamedThing	negative regulation of humoral immune response	Any process that stops, prevents, or reduces the frequency, rate, or extent of a humoral immune response.	tmpzr1t_l9r_go_relaxed.owl	inhibition of humoral immune response|downregulation of humoral immune response|down regulation of humoral immune response|down-regulation of humoral immune response													biological_process											owl:Class	
GO:0008490	biolink:NamedThing	arsenite secondary active transmembrane transporter activity	Enables the transfer of arsenite from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters.	tmpzr1t_l9r_go_relaxed.owl	arsenite porter activity											GO:0008491		molecular_function											owl:Class	
GO:0001888	biolink:NamedThing	glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity	Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + beta-D-glucuronosyl-(1->3)-beta-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-xylosyl-proteoglycan = UDP + alpha-N-acetyl-D-glucosaminyl-(1->4)-beta-D-glucuronosyl-(1->3)-beta-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-xylosyl-proteoglycan.	tmpzr1t_l9r_go_relaxed.owl	glucuronosylgalactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity|UDP-N-acetyl-D-glucosamine:beta-D-glucuronosyl-(1->3)-beta-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-xylosyl-proteoglycan 4IV-alpha-N-acetyl-D-glucosaminyltransferase activity|UDP-N-acetyl-D-glucosamine:beta-D-glucuronosyl-(1,3)-beta-D-galactosyl-(1,3)-beta-D-galactosyl-(1,4)-beta-D-xylosyl-proteoglycan 4IV-alpha-N-acetyl-D-glucosaminyltransferase activity|alpha1,4-N-acetylglucosaminyltransferase activity|alpha-1,4-N-acetylglucosaminyltransferase activity|alpha-N-acetylglucosaminyltransferase I activity				EC:2.4.1.223|RHEA:16221|MetaCyc:2.4.1.223-RXN									molecular_function											owl:Class	
GO:0031643	biolink:NamedThing	positive regulation of myelination	Any process that activates or increases the frequency, rate or extent of the formation of a myelin sheath around nerve axons.	tmpzr1t_l9r_go_relaxed.owl	up regulation of myelination|up-regulation of myelination|activation of myelination|upregulation of myelination|stimulation of myelination													biological_process											owl:Class	
GO:0030204	biolink:NamedThing	chondroitin sulfate metabolic process	The chemical reactions and pathways involving chondroitin sulfate, any member of a group of 10-60 kDa glycosaminoglycans, widely distributed in cartilage and other mammalian connective tissues, the repeat units of which consist of beta-(1,4)-linked D-glucuronyl beta-(1,3)-N-acetyl-D-galactosamine sulfate. They usually occur linked to a protein to form proteoglycans. Two subgroups exist, one in which the sulfate is on the 4-position (chondroitin sulfate A) and the second in which it is in the 6-position (chondroitin sulfate C). They often are polydisperse and often differ in the degree of sulfation from tissue to tissue. The chains of repeating disaccharide are covalently linked to the side chains of serine residues in the polypeptide backbone of a protein by a glycosidic attachment through the trisaccharide unit galactosyl-galactosyl-xylosyl. Chondroitin sulfate B is more usually known as dermatan sulfate.	tmpzr1t_l9r_go_relaxed.owl	chondroitin sulphate metabolism|chondroitin sulphate metabolic process|chondroitin sulfate metabolism													biological_process											owl:Class	
GO:0060202	biolink:NamedThing	clathrin-sculpted acetylcholine transport vesicle lumen	The volume enclosed by the membrane of the clathrin-sculpted acetylcholine transport vesicle.	tmpzr1t_l9r_go_relaxed.owl	clathrin sculpted acetylcholine transport vesicle lumen|clathrin sculpted acetylcholine constitutive secretory pathway transport vesicle lumen													cellular_component											owl:Class	
GO:1904894	biolink:NamedThing	positive regulation of receptor signaling pathway via STAT	Any process that activates or increases the frequency, rate or extent of receptor signaling pathway via STAT.	tmpzr1t_l9r_go_relaxed.owl	up regulation of STAT cascade|upregulation of kinase activated-STAT cascade|up regulation of kinase activated-STAT cascade|positive regulation of STAT signalling pathway|positive regulation of kinase activated-STAT cascade|up regulation of STAT signalling pathway|activation of kinase-STAT cascade|activation of kinase activated-STAT cascade|upregulation of kinase-STAT cascade|up-regulation of kinase-STAT cascade|up-regulation of STAT cascade|up-regulation of kinase activated-STAT cascade|upregulation of STAT cascade|up regulation of kinase-STAT cascade|upregulation of STAT signalling pathway|positive regulation of kinase-STAT cascade|activation of STAT signalling pathway|up-regulation of STAT signalling pathway|activation of STAT cascade							pr	2016-01-08T08:14:48Z					biological_process											owl:Class	
GO:0051429	biolink:NamedThing	corticotropin-releasing hormone receptor binding	Binding to a receptor for corticotropin-releasing hormone (CRH), a polypeptide hormone involved in the stress response. It is released by the hypothalamus and stimulates the release of corticotropin by the anterior pituitary gland.	tmpzr1t_l9r_go_relaxed.owl	corticotropin releasing factor receptor ligand|CRH receptor binding|corticotropin-releasing factor receptor binding|CRHR binding|CRF receptor binding|corticotropin releasing factor receptor binding											GO:0031742		molecular_function											owl:Class	
GO:1902090	biolink:NamedThing	regulation of fumagillin biosynthetic process	Any process that modulates the frequency, rate or extent of fumagillin biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of fumagillin biosynthesis|regulation of fumagillin anabolism|regulation of fumagillin synthesis|regulation of fumagillin formation							di	2013-04-27T03:44:59Z					biological_process											owl:Class	
GO:0031708	biolink:NamedThing	endothelin B receptor binding	Binding to an endothelin B receptor.	tmpzr1t_l9r_go_relaxed.owl	endothelin B receptor ligand													molecular_function											owl:Class	
GO:0031705	biolink:NamedThing	bombesin receptor binding	Binding to a bombesin receptor.	tmpzr1t_l9r_go_relaxed.owl	bombesin receptor ligand													molecular_function											owl:Class	
GO:1990591	biolink:NamedThing	asparagine transmembrane import into vacuole	The directed movement of asparagine into the vacuole across the vacuolar membrane.	tmpzr1t_l9r_go_relaxed.owl								vw	2014-12-15T16:33:46Z					biological_process											owl:Class	
GO:0052900	biolink:NamedThing	spermine oxidase (propane-1,3-diamine-forming) activity	Catalysis of the reaction: H(2)O + O(2) + spermine = 1,3-diaminopropane + H(2)O(2) + N-(3-aminopropyl)-4-aminobutanal.	tmpzr1t_l9r_go_relaxed.owl	polyamine oxidase (propane-1,3-diamine-forming) activity				RHEA:25824|EC:1.5.3.14|MetaCyc:RXN-6421									molecular_function											owl:Class	
GO:0002437	biolink:NamedThing	inflammatory response to antigenic stimulus	An inflammatory response to an antigenic stimulus, which can be include any number of T cell or B cell epitopes.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1904807	biolink:NamedThing	negative regulation of protein oxidation	Any process that stops, prevents or reduces the frequency, rate or extent of protein oxidation.	tmpzr1t_l9r_go_relaxed.owl	down regulation of protein oxidation|down-regulation of protein amino acid oxidation|inhibition of protein amino acid oxidation|inhibition of protein oxidation|downregulation of protein amino acid oxidation|negative regulation of protein amino acid oxidation|downregulation of protein oxidation|down regulation of protein amino acid oxidation|down-regulation of protein oxidation							mec	2015-11-10T14:06:08Z					biological_process											owl:Class	
GO:1904806	biolink:NamedThing	regulation of protein oxidation	Any process that modulates the frequency, rate or extent of protein oxidation.	tmpzr1t_l9r_go_relaxed.owl	regulation of protein amino acid oxidation							mec	2015-11-10T14:06:00Z					biological_process											owl:Class	
GO:0010312	biolink:NamedThing	detoxification of zinc ion	Any process that reduces or removes the toxicity of zinc ion. These include transport of zinc away from sensitive areas and to compartments or complexes whose purpose is sequestration of zinc ion.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:2000276	biolink:NamedThing	negative regulation of oxidative phosphorylation uncoupler activity	Any process that stops, prevents or reduces the frequency, rate or extent of oxidative phosphorylation uncoupler activity.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of uncoupling protein activity|negative regulation of mitochondrial uncoupling protein activity							mah	2010-12-07T12:14:59Z					biological_process											owl:Class	
GO:0031555	biolink:NamedThing	transcriptional attenuation	Regulation of transcription through variation in where transcription termination occurs.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Attenuator_(genetics)									biological_process											owl:Class	
GO:0035219	biolink:NamedThing	prothoracic disc development	Progression of the prothoracic disc over time, from its initial formation through to its metamorphosis to form the adult humerous and anterior spiracle.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1905156	biolink:NamedThing	negative regulation of photosynthesis	Any process that stops, prevents or reduces the frequency, rate or extent of photosynthesis.	tmpzr1t_l9r_go_relaxed.owl	down regulation of photosynthesis|inhibition of photosynthesis|downregulation of photosynthesis|down-regulation of photosynthesis							tb	2016-04-19T16:12:29Z					biological_process											owl:Class	
GO:1904640	biolink:NamedThing	response to methionine	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methionine stimulus.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-08-31T17:23:56Z					biological_process											owl:Class	
GO:0032226	biolink:NamedThing	positive regulation of synaptic transmission, dopaminergic	Any process that activates, maintains or increases the frequency, rate or extent of dopaminergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter dopamine.	tmpzr1t_l9r_go_relaxed.owl	stimulation of synaptic transmission, dopaminergic|up regulation of synaptic transmission, dopaminergic|upregulation of synaptic transmission, dopaminergic|activation of synaptic transmission, dopaminergic|up-regulation of synaptic transmission, dopaminergic													biological_process											owl:Class	
GO:0006236	biolink:NamedThing	cytidine salvage	Any process that generates cytidine, cytosine riboside, from derivatives of it without de novo synthesis.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0043097	biolink:NamedThing	pyrimidine nucleoside salvage	Any process that generates a pyrimidine nucleoside, one of a family of organic molecules consisting of a pyrimidine base covalently bonded to a sugar ribose, from derivatives of it, without de novo synthesis.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:2001138	biolink:NamedThing	regulation of phospholipid transport	Any process that modulates the frequency, rate or extent of phospholipid transport.	tmpzr1t_l9r_go_relaxed.owl								kmv	2011-10-14T06:16:06Z					biological_process											owl:Class	
GO:0016263	biolink:NamedThing	glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity	Catalysis of the addition of a galactosyl residue to a non-reducing O-linked N-acetylgalactosamine residue in an O-glycan.	tmpzr1t_l9r_go_relaxed.owl	UDP-galactose:glycoprotein-N-acetyl-D-galactosamine 3-beta-D-galactosyltransferase activity|Core 1 GalT|uridine diphosphogalactose-mucin beta-(1->3)-galactosyltransferase activity|UDPgalactose:glycoprotein-N-acetyl-D-galactosamine 3-beta-D-galactosyltransferase activity				EC:2.4.1.122|Reactome:R-HSA-6785524|MetaCyc:2.4.1.122-RXN|RHEA:15621|Reactome:R-HSA-1964505									molecular_function											owl:Class	
GO:0006065	biolink:NamedThing	UDP-glucuronate biosynthetic process	The chemical reactions and pathways resulting in the formation of UDP-glucuronate, a substance composed of glucuronic acid in glycosidic linkage with uridine diphosphate.	tmpzr1t_l9r_go_relaxed.owl	UDP-glucuronate formation|UDP-glucuronate synthesis|UDP-glucuronate biosynthesis|UDP-glucuronate anabolism				MetaCyc:PWY-4841									biological_process											owl:Class	
GO:0071062	biolink:NamedThing	alphav-beta3 integrin-vitronectin complex	A protein complex that consists of an alphav-beta3 integrin complex bound to vitronectin.	tmpzr1t_l9r_go_relaxed.owl	ITGAV-ITGB3-VTN complex							mah	2009-11-03T04:02:57Z					cellular_component											owl:Class	
GO:0004413	biolink:NamedThing	homoserine kinase activity	Catalysis of the reaction: L-homoserine + ATP = O-phospho-L-homoserine + ADP + 2 H(+).	tmpzr1t_l9r_go_relaxed.owl	homoserine kinase (phosphorylating)|HSK|ATP:L-homoserine O-phosphotransferase activity				MetaCyc:HOMOSERKIN-RXN|RHEA:13985|EC:2.7.1.39|KEGG_REACTION:R01771									molecular_function											owl:Class	
GO:0032504	biolink:NamedThing	multicellular organism reproduction	The biological process in which new individuals are produced by one or two multicellular organisms. The new individuals inherit some proportion of their genetic material from the parent or parents.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0051545	biolink:NamedThing	negative regulation of elastin biosynthetic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of elastin.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of elastin biosynthetic process|downregulation of elastin biosynthetic process|down regulation of elastin biosynthetic process|inhibition of elastin biosynthetic process													biological_process											owl:Class	
GO:0098717	biolink:NamedThing	pantothenate import across plasma membrane	The directed movement of pantothenate from outside of a cell, across the plasma membrane and into the cytosol.	tmpzr1t_l9r_go_relaxed.owl	pantothenate import|pantothenate import into cell							jl	2012-12-06T13:02:23Z			GO:0044755|GO:1901688		biological_process											owl:Class	
GO:0031727	biolink:NamedThing	CCR2 chemokine receptor binding	Binding to a CCR2 chemokine receptor.	tmpzr1t_l9r_go_relaxed.owl	monocyte chemoattractant protein 1 receptor binding|CCR2 chemokine receptor ligand													molecular_function											owl:Class	
GO:0048020	biolink:NamedThing	CCR chemokine receptor binding	Binding to a CCR chemokine receptor.	tmpzr1t_l9r_go_relaxed.owl	beta chemokine receptor ligand|beta chemokine receptor binding|CCR chemokine receptor ligand													molecular_function											owl:Class	
GO:0047031	biolink:NamedThing	diethyl 2-methyl-3-oxosuccinate reductase activity	Catalysis of the reaction: diethyl (2R,3R)-2-methyl-3-hydroxysuccinate + NADP(+) = diethyl 2-methyl-3-oxosuccinate + H(+) + NADPH.	tmpzr1t_l9r_go_relaxed.owl	diethyl-(2R,3R)-2-methyl-3-hydroxysuccinate:NADP+ 3-oxidoreductase activity				KEGG_REACTION:R04387|EC:1.1.1.229|MetaCyc:1.1.1.229-RXN|RHEA:21008									molecular_function											owl:Class	
GO:0102676	biolink:NamedThing	avenasterol-desaturase activity	Catalysis of the reaction: avenasterol + O2 + NADPH + H+ <=> 5-dehydroavenasterol + 2 H2O + NADP.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-4209									molecular_function											owl:Class	
GO:2001222	biolink:NamedThing	regulation of neuron migration	Any process that modulates the frequency, rate or extent of neuron migration.	tmpzr1t_l9r_go_relaxed.owl	regulation of neuron guidance|regulation of neuron chemotaxis|regulation of neuronal migration							kmv	2011-11-17T10:01:38Z					biological_process											owl:Class	
GO:0099611	biolink:NamedThing	regulation of action potential firing threshold	Any process that regulates the potential at which an axon potential is triggered.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0046029	biolink:NamedThing	mannitol dehydrogenase activity	Catalysis of the reaction: D-mannitol + NAD(+) = D-mannose + H(+) + NADH.	tmpzr1t_l9r_go_relaxed.owl	MTD activity|mannitol:NAD+ 1-oxidoreductase activity|NAD-dependent mannitol dehydrogenase activity				RHEA:15029|EC:1.1.1.255|KEGG_REACTION:R07135|MetaCyc:1.1.1.255-RXN									molecular_function											owl:Class	
GO:0033102	biolink:NamedThing	acidocalcisome membrane	The lipid bilayer surrounding an acidocalcisome.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0070909	biolink:NamedThing	glutamate:gamma-aminobutyric acid antiporter activity	Catalysis of the reaction: glutamate(out) + gamma-aminobutyric acid(in) = glutamate(in) + gamma-aminobutyric acid(out).	tmpzr1t_l9r_go_relaxed.owl	glutamate-gamma-aminobutyric acid antiporter activity|glutamate: GABA antiporter activity|glutamate/gamma-aminobutyric acid antiporter activity							mah	2009-09-04T03:51:32Z					molecular_function											owl:Class	
GO:0045797	biolink:NamedThing	positive regulation of intestinal cholesterol absorption	Any process that activates or increases the frequency, rate or extent of uptake of cholesterol into the blood by absorption from the intestine.	tmpzr1t_l9r_go_relaxed.owl	up regulation of cholesterol absorption|activation of cholesterol absorption|upregulation of cholesterol absorption|up-regulation of cholesterol absorption|stimulation of cholesterol absorption													biological_process											owl:Class	
GO:0032376	biolink:NamedThing	positive regulation of cholesterol transport	Any process that activates or increases the frequency, rate or extent of the directed movement of cholesterol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	activation of cholesterol transport|up regulation of cholesterol transport|stimulation of cholesterol transport|upregulation of cholesterol transport|up-regulation of cholesterol transport													biological_process											owl:Class	
GO:0021644	biolink:NamedThing	vagus nerve morphogenesis	The process in which the anatomical structure of the vagus nerve is generated and organized. This nerve is primarily sensory but also has visceromotor components. It originates in the brain stem and controls many autonomic functions of the heart, lungs, stomach, pharynx, larynx, trachea, esophagus and other gastrointestinal tract components. It controls some motor functions such as speech. The sensory branches mediate sensation from the pharynx, larynx, thorax and abdomen; it also innervates taste buds in the epiglottis.	tmpzr1t_l9r_go_relaxed.owl	CN X morphogenesis													biological_process											owl:Class	
GO:0033315	biolink:NamedThing	meiotic G2/MI DNA replication checkpoint signaling	A signal transduction process that controls the G2/M1 transition of the meiotic cell cycle and prevents the initiation of nuclear division until DNA replication is complete.	tmpzr1t_l9r_go_relaxed.owl	meiotic cell cycle DNA replication checkpoint|meiotic G2/MI DNA replication checkpoint|signal transduction involved in meiotic DNA replication checkpoint	https://github.com/geneontology/go-ontology/issues/20935										GO:0072440		biological_process											owl:Class	
GO:0044778	biolink:NamedThing	meiotic DNA integrity checkpoint signaling	A signal transduction process that controls cell cycle progression in response to changes in DNA structure by monitoring the integrity of the DNA during meiosis. The DNA integrity checkpoint begins with detection of DNA damage, defects in DNA structure or DNA replication, and ends with signal transduction.	tmpzr1t_l9r_go_relaxed.owl	meiotic DNA integrity checkpoint	https://github.com/geneontology/go-ontology/issues/20935						jl	2013-03-20T16:46:06Z					biological_process											owl:Class	
GO:0140076	biolink:NamedThing	negative regulation of lipoprotein transport	Any process that stops, prevents or reduces the frequency, rate or extent of lipoprotein transport.	tmpzr1t_l9r_go_relaxed.owl								pg	2017-07-21T15:39:50Z					biological_process											owl:Class	
GO:0140075	biolink:NamedThing	regulation of lipoprotein transport	Any process that controls lipoprotein transport.	tmpzr1t_l9r_go_relaxed.owl								pg	2017-07-21T15:35:47Z					biological_process											owl:Class	
GO:1902821	biolink:NamedThing	1-undecene biosynthetic process	The chemical reactions and pathways resulting in the formation of 1-undecene.	tmpzr1t_l9r_go_relaxed.owl	1-undecene biosynthesis|1-undecene synthesis|1-undecene formation|1-undecene anabolism							tt	2014-03-31T02:51:19Z					biological_process											owl:Class	
GO:0099624	biolink:NamedThing	atrial cardiac muscle cell membrane repolarization	The process in which ions are transported across the plasma membrane of an atrial cardiac muscle cell such that the membrane potential changes in the repolarizing direction, toward the steady state potential. For example, the repolarization during an action potential is from a positive membrane potential towards a negative resting potential.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0102035	biolink:NamedThing	isobutyryl-CoA:FAD oxidoreductase activity	Catalysis of the reaction: H+ + isobutyryl-CoA + FAD <=> methacrylyl-CoA + FADH2.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:MEPROPCOA-FAD-RXN|EC:1.3.8.5									molecular_function											owl:Class	
GO:0033060	biolink:NamedThing	ocellus pigmentation	The deposition or aggregation of coloring matter in an ocellus, a minute simple eye found in many invertebrates.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0001618	biolink:NamedThing	virus receptor activity	Combining with a virus component and mediating entry of the virus into the cell.	tmpzr1t_l9r_go_relaxed.owl	viral receptor activity													molecular_function											owl:Class	
GO:0140272	biolink:NamedThing	exogenous protein binding	Binding to a protein or protein complex from a different species, for example a pathogen molecule binding to a host protein.	tmpzr1t_l9r_go_relaxed.owl						Note that as GO captures normal processes, it may be that exogenous proteins interactions are normal for one of the participating species but not the other. Therefore reciprocal annotations should not be made without confirming that it is physiological relevant.		pg	2018-10-01T10:03:21Z					molecular_function											owl:Class	
GO:0045761	biolink:NamedThing	regulation of adenylate cyclase activity	Any process that modulates the frequency, rate or extent of adenylate cyclase activity.	tmpzr1t_l9r_go_relaxed.owl	regulation of adenylyl cyclase activity|adenylate cyclase regulator													biological_process											owl:Class	
GO:0051339	biolink:NamedThing	regulation of lyase activity	Any process that modulates the frequency, rate or extent of lyase activity, the catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond. They differ from other enzymes in that two substrates are involved in one reaction direction, but only one in the other direction. When acting on the single substrate, a molecule is eliminated and this generates either a new double bond or a new ring.	tmpzr1t_l9r_go_relaxed.owl	lyase regulator													biological_process											owl:Class	
GO:0110079	biolink:NamedThing	regulation of placenta blood vessel development	Any process that modulates the frequency, rate or extent of placenta blood vessel development.	tmpzr1t_l9r_go_relaxed.owl								kmv	2018-02-01T14:49:12Z					biological_process											owl:Class	
GO:0050172	biolink:NamedThing	phenylalanine 2-monooxygenase activity	Catalysis of the reaction: L-phenylalanine + O(2) = 2-phenylacetamide + CO(2) + H(2)O.	tmpzr1t_l9r_go_relaxed.owl	L-phenylalanine:oxygen 2-oxidoreductase (decarboxylating)|phenylalanine (deaminating, decarboxylating)oxidase activity|phenylalanine (deaminating, decarboxylating) oxidase activity|L-phenylalanine oxidase (deaminating and decarboxylating)|l-phenylalanine oxidase (deaminating and decarboxylating) activity				KEGG_REACTION:R00690|EC:1.13.12.9|MetaCyc:PHENYLALANINE-2-MONOOXYGENASE-RXN|RHEA:10712									molecular_function											owl:Class	
GO:1905663	biolink:NamedThing	positive regulation of telomerase RNA reverse transcriptase activity	Any process that activates or increases the frequency, rate or extent of telomerase RNA reverse transcriptase activity.	tmpzr1t_l9r_go_relaxed.owl	upregulation of telomerase, catalyst|upregulation of telomerase RNA reverse transcriptase activity|up regulation of telomerase, catalyst|activation of telomerase RNA reverse transcriptase activity|positive regulation of telomerase, catalyst|up regulation of telomerase RNA reverse transcriptase activity|activation of telomerase, catalyst|up-regulation of telomerase, catalyst|up-regulation of telomerase RNA reverse transcriptase activity							nc	2016-11-09T16:55:35Z					biological_process											owl:Class	
GO:1905638	biolink:NamedThing	negative regulation of mitochondrial mRNA catabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrial mRNA catabolic process.	tmpzr1t_l9r_go_relaxed.owl	downregulation of mitochondrial mRNA catabolic process|down-regulation of mitochondrial mRNA catabolic process|down regulation of mitochondrial mRNA catabolic process|inhibition of mitochondrial mRNA catabolic process							tb	2016-11-03T20:24:05Z					biological_process											owl:Class	
GO:0048019	biolink:NamedThing	receptor antagonist activity	The activity of a gene product that interacts with a receptor to decrease the ability of the receptor agonist to bind and activate the receptor.	tmpzr1t_l9r_go_relaxed.owl	receptor ligand activity													molecular_function											owl:Class	
GO:0009403	biolink:NamedThing	toxin biosynthetic process	The chemical reactions and pathways resulting in the formation of toxin, a poisonous compound (typically a protein) that is produced by cells or organisms and that can cause disease when introduced into the body or tissues of an organism.	tmpzr1t_l9r_go_relaxed.owl	toxin anabolism|toxin synthesis|toxin formation|toxin biosynthesis													biological_process											owl:Class	
GO:1901640	biolink:NamedThing	XTP binding	Binding to XTP.	tmpzr1t_l9r_go_relaxed.owl								tb	2012-11-15T22:56:35Z					molecular_function											owl:Class	
GO:0102057	biolink:NamedThing	jasmonoyl-valine synthetase activity	Catalysis of the reaction: L-valine  + ATP(4-) + a jasmonic acid <=> AMP(2-) + diphosphoric acid + a jasmonoyl-valine.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-10457|EC:6.3.2.52|RHEA:55772									molecular_function											owl:Class	
GO:1901968	biolink:NamedThing	regulation of polynucleotide 3'-phosphatase activity	Any process that modulates the frequency, rate or extent of polynucleotide 3'-phosphatase activity.	tmpzr1t_l9r_go_relaxed.owl	regulation of 5'-polynucleotidekinase 3'-phosphatase activity|regulation of 2'(3')-polynucleotidase activity|regulation of deoxyribonucleate 3'-phosphatase activity|regulation of DNA 3'-phosphatase activity|regulation of polynucleotide 3'-phosphohydrolase activity							tb	2013-02-22T00:58:17Z					biological_process											owl:Class	
GO:0032346	biolink:NamedThing	positive regulation of aldosterone metabolic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving aldosterone.	tmpzr1t_l9r_go_relaxed.owl	upregulation of aldosterone metabolic process|stimulation of aldosterone metabolic process|up regulation of aldosterone metabolic process|activation of aldosterone metabolic process|positive regulation of aldosterone metabolism|up-regulation of aldosterone metabolic process													biological_process											owl:Class	
GO:0007178	biolink:NamedThing	transmembrane receptor protein serine/threonine kinase signaling pathway	A series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell where the receptor possesses serine/threonine kinase activity, and ending with regulation of a downstream cellular process, e.g. transcription.	tmpzr1t_l9r_go_relaxed.owl	transmembrane receptor protein serine/threonine kinase signalling pathway													biological_process											owl:Class	
GO:1900904	biolink:NamedThing	positive regulation of hexadecanal biosynthetic process	Any process that activates or increases the frequency, rate or extent of hexadecanal biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of hexadecanal biosynthetic process|activation of hexadecanal anabolism|positive regulation of palmitaldehyde biosynthesis|upregulation of hexadecanal anabolism|activation of hexadecanal synthesis|upregulation of hexadecanal biosynthesis|upregulation of hexadecanal biosynthetic process|activation of palmitaldehyde biosynthetic process|activation of hexadecanal biosynthesis|up-regulation of palmitaldehyde biosynthesis|positive regulation of palmitaldehyde biosynthetic process|up-regulation of hexadecanal formation|upregulation of hexadecanal synthesis|activation of palmitaldehyde biosynthesis|activation of hexadecanal formation|positive regulation of hexadecanal synthesis|up-regulation of hexadecanal biosynthesis|activation of hexadecanal biosynthetic process|up-regulation of hexadecanal anabolism|up-regulation of hexadecanal synthesis|up regulation of hexadecanal synthesis|up regulation of hexadecanal formation|positive regulation of hexadecanal formation|upregulation of palmitaldehyde biosynthesis|positive regulation of hexadecanal anabolism|up-regulation of palmitaldehyde biosynthetic process|upregulation of palmitaldehyde biosynthetic process|positive regulation of hexadecanal biosynthesis|upregulation of hexadecanal formation|up regulation of palmitaldehyde biosynthetic process|up regulation of hexadecanal biosynthetic process|up regulation of hexadecanal anabolism|up regulation of hexadecanal biosynthesis|up regulation of palmitaldehyde biosynthesis							tt	2012-06-13T03:33:42Z					biological_process											owl:Class	
GO:1900907	biolink:NamedThing	positive regulation of hexadecanal metabolic process	Any process that activates or increases the frequency, rate or extent of hexadecanal metabolic process.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of hexadecanal metabolic process|up regulation of hexadecanal metabolic process|up-regulation of hexadecanal metabolism|up regulation of hexadecanal metabolism|upregulation of hexadecanal metabolic process|positive regulation of hexadecanal metabolism|activation of hexadecanal metabolism|upregulation of hexadecanal metabolism|activation of hexadecanal metabolic process							tt	2012-06-13T03:36:02Z					biological_process											owl:Class	
GO:0033332	biolink:NamedThing	ent-kaurene biosynthetic process	The chemical reactions and pathways resulting in the formation of ent-kaurene. Ent-kaurene is a tetracyclic diterpenoid that is a precursor of several plant isoprenoids, including gibberellins.	tmpzr1t_l9r_go_relaxed.owl	ent-kaurene synthesis|ent-kaurene anabolism|ent-kaurene biosynthesis|ent-kaurene formation				MetaCyc:PWY-5035|MetaCyc:PWY-5032									biological_process											owl:Class	
GO:0033331	biolink:NamedThing	ent-kaurene metabolic process	The chemical reactions and pathways involving ent-kaur-16-ene. Ent-kaurene is a tetracyclic diterpenoid that is a precursor of several plant isoprenoids, including gibberellins.	tmpzr1t_l9r_go_relaxed.owl	ent-kaurene metabolism													biological_process											owl:Class	
GO:0120195	biolink:NamedThing	positive regulation of anther dehiscence	Any process that activates or increases the frequency, rate or extent of anther dehiscence.	tmpzr1t_l9r_go_relaxed.owl								krc	2019-04-09T21:58:31Z					biological_process											owl:Class	
GO:0030919	biolink:NamedThing	peptidyl-serine O-acetylation	The acetylation of peptidyl-serine to form peptidyl-O-acetyl-L-serine.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0364									biological_process											owl:Class	
GO:0036253	biolink:NamedThing	response to amiloride	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amiloride stimulus.	tmpzr1t_l9r_go_relaxed.owl								bf	2012-06-15T01:05:35Z					biological_process											owl:Class	
GO:0042670	biolink:NamedThing	retinal cone cell differentiation	The process in which a relatively unspecialized cell acquires the specialized features of a retinal cone cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0035248	biolink:NamedThing	alpha-1,4-N-acetylgalactosaminyltransferase activity	Catalysis of the transfer of an N-acetylgalactosaminyl residue from UDP-N-acetyl-galactosamine to an acceptor molecule, forming an alpha-1,4 linkage.	tmpzr1t_l9r_go_relaxed.owl	alpha-1,4-GalNAc transferase activity													molecular_function											owl:Class	
GO:1904245	biolink:NamedThing	regulation of polynucleotide adenylyltransferase activity	Any process that modulates the frequency, rate or extent of polynucleotide adenylyltransferase activity.	tmpzr1t_l9r_go_relaxed.owl	regulation of adenosine triphosphate:ribonucleic acid adenylyltransferase activity|regulation of polyadenylate nucleotidyltransferase activity|regulation of AMP polynucleotidylexotransferase activity|regulation of RNA formation factors, PF1|regulation of polyadenylate synthetase activity|regulation of poly(A) synthetase activity|regulation of poly-A polymerase activity|regulation of polyadenylic acid polymerase activity|regulation of RNA adenylating enzyme activity|regulation of terminal riboadenylate transferase activity|regulation of ATP-polynucleotide adenylyltransferase activity|regulation of ATP:polynucleotidylexotransferase activity|regulation of NTP polymerase activity|regulation of ATP:polynucleotide adenylyltransferase activity|regulation of polyadenylic polymerase activity|regulation of poly(A) hydrolase activity|regulation of polyadenylate polymerase activity|regulation of poly(A) polymerase activity							kmv	2015-05-19T14:47:20Z					biological_process											owl:Class	
GO:0090334	biolink:NamedThing	regulation of cell wall (1->3)-beta-D-glucan biosynthetic process	Any process that modulates the rate, frequency, or extent of the chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds, found in the walls of cells.	tmpzr1t_l9r_go_relaxed.owl	regulation of cell wall 1,3-beta-glucan biosynthetic process|regulation of cell wall 1,3-beta-D-glucan biosynthetic process							tb	2010-06-01T03:11:34Z					biological_process											owl:Class	
GO:1903338	biolink:NamedThing	regulation of cell wall organization or biogenesis	Any process that modulates the frequency, rate or extent of cell wall organization or biogenesis.	tmpzr1t_l9r_go_relaxed.owl	regulation of cell wall organization or biogenesis at cellular level|regulation of cellular cell wall organization or biogenesis|regulation of cellular cell wall organisation or biogenesis|regulation of cell wall organisation or biogenesis							vw	2014-08-18T13:20:50Z					biological_process											owl:Class	
GO:1990884	biolink:NamedThing	RNA acetylation	The posttranscriptional addition of one or more acetyl groups to specific residues in an RNA molecule.	tmpzr1t_l9r_go_relaxed.owl								mah	2015-10-28T16:28:08Z					biological_process											owl:Class	
GO:0031541	biolink:NamedThing	negative regulation of anthocyanin biosynthetic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of anthocyanins.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of anthocyanin synthesis|downregulation of anthocyanin biosynthetic process|negative regulation of anthocyanin formation|down regulation of anthocyanin biosynthetic process|negative regulation of anthocyanin biosynthesis|inhibition of anthocyanin biosynthetic process|negative regulation of anthocyanin anabolism|down-regulation of anthocyanin biosynthetic process													biological_process											owl:Class	
GO:0098644	biolink:NamedThing	complex of collagen trimers	A complex of collagen trimers such as a fibril or collagen network.	tmpzr1t_l9r_go_relaxed.owl	Supramolecular collagen assembly|Supramolecular aggregate of collagen													cellular_component											owl:Class	
GO:0039521	biolink:NamedThing	suppression by virus of host autophagy	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of autophagy in the host.	tmpzr1t_l9r_go_relaxed.owl	inhibition by virus of host autophagy|inhibition of host autophagy by virus|negative regulation by virus of host autophagy				VZ:845			bf	2011-06-22T04:30:11Z					biological_process											owl:Class	
GO:1990189	biolink:NamedThing	peptide-serine-N-acetyltransferase activity	Catalysis of the reaction: acetyl-CoA + N-terminal L-serine in peptide = CoA + N-acetyl-L-serine-peptide.	tmpzr1t_l9r_go_relaxed.owl								tb	2013-09-11T20:13:40Z					molecular_function											owl:Class	
GO:0008176	biolink:NamedThing	tRNA (guanine-N7-)-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing N7-methylguanine.	tmpzr1t_l9r_go_relaxed.owl	S-adenosyl-L-methionine:tRNA (guanine-N7-)-methyltransferase activity|N7-methylguanine methylase activity|7-methylguanine transfer ribonucleate methylase activity|tRNA guanine 7-methyltransferase activity|transfer ribonucleate guanine 7-methyltransferase activity|S-adenosyl-L-methionine:tRNA (guanine-7-N-)-methyltransferase activity				Reactome:R-HSA-6782286|EC:2.1.1.33|MetaCyc:TRNA-GUANINE-N7--METHYLTRANSFERASE-RXN|RHEA:42708									molecular_function											owl:Class	
GO:0016423	biolink:NamedThing	tRNA (guanine) methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing methylguanine.	tmpzr1t_l9r_go_relaxed.owl	tRNA (guanosine) methyltransferase activity											GO:0016424		molecular_function											owl:Class	
GO:2000966	biolink:NamedThing	regulation of cell wall polysaccharide catabolic process	Any process that modulates the frequency, rate or extent of cell wall polysaccharide catabolic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of cell wall polysaccharide breakdown							tt	2011-08-01T02:30:27Z					biological_process											owl:Class	
GO:1902289	biolink:NamedThing	negative regulation of defense response to oomycetes	Any process that stops, prevents or reduces the frequency, rate or extent of defense response to oomycetes.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of defense response to oomycetes|downregulation of defense response to oomycetes|down regulation of defense response to oomycetes|inhibition of defense response to oomycetes							ms	2013-07-09T13:45:37Z					biological_process											owl:Class	
GO:0034789	biolink:NamedThing	2-hydroxy-6-oxo-6-(2-carboxyphenyl)-hexa-2,4-dienoate hydrolase activity	Catalysis of the reaction: 2-hydroxy-6-oxo-6-(2-carboxyphenyl)-hexa-2,4-dienoate + H2O = cis-2-hydroxypenta-2,4-dienoate + phthalate + H+.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r1042									molecular_function											owl:Class	
GO:0033819	biolink:NamedThing	lipoyl(octanoyl) transferase activity	Catalysis of the reaction: octanoyl-[acyl-carrier protein] + protein = protein N6-(octanoyl)lysine + acyl-carrier protein.	tmpzr1t_l9r_go_relaxed.owl	lipoate/octanoate transferase activity|LipB|octanoyl-acyl carrier protein-protein N-octanoyltransferase activity|octanoyl-acyl-carrier-protein-protein N-octanoyltransferase activity|lipoyl (octanoyl)-acyl carrier protein:protein transferase activity|lipoyl (octanoyl)-acyl-carrier-protein-protein N-lipoyltransferase activity|octanoyl-acyl-carrier-protein:protein N-octanoyltransferase activity				EC:2.3.1.181|Reactome:R-HSA-6793590|MetaCyc:RXN0-947									molecular_function											owl:Class	
GO:1904517	biolink:NamedThing	MgATP(2-) binding	Binding to MgATP(2-).	tmpzr1t_l9r_go_relaxed.owl								bhm	2015-07-29T13:40:02Z					molecular_function											owl:Class	
GO:1902244	biolink:NamedThing	cis-abienol metabolic process	The chemical reactions and pathways involving cis-abienol.	tmpzr1t_l9r_go_relaxed.owl	cis-abienol metabolism							ms	2013-06-20T09:09:51Z					biological_process											owl:Class	
GO:0001939	biolink:NamedThing	female pronucleus	The pronucleus originating from the ovum that is being fertilized.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0045120	biolink:NamedThing	pronucleus	The nucleus of either the ovum or the spermatozoon following fertilization. Thus, in the fertilized ovum, there are two pronuclei, one originating from the ovum, the other from the spermatozoon that brought about fertilization; they approach each other, but do not fuse until just before the first cleavage, when each pronucleus loses its membrane to release its contents.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Pronucleus									cellular_component											owl:Class	
GO:0007509	biolink:NamedThing	mesoderm migration involved in gastrulation	The migration of mesodermal cells during gastrulation to help establish the multilayered body plan of the organism.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0008078	biolink:NamedThing	mesodermal cell migration	The orderly movement of mesodermal cells from one site to another.	tmpzr1t_l9r_go_relaxed.owl	mesoderm cell migration													biological_process											owl:Class	
GO:0070024	biolink:NamedThing	CD19-Vav-PIK3R1 complex	A protein complex that contains the cell surface signaling molecule CD19, the Ras guanine nucleotide exchange factor Vav, and the regulatory subunit alpha of phosphatidylinositol 3-kinase (PI3K).	tmpzr1t_l9r_go_relaxed.owl	CD19-Vav-PI 3-kinase (p85 subunit) complex													cellular_component											owl:Class	
GO:0006042	biolink:NamedThing	glucosamine biosynthetic process	The chemical reactions and pathways resulting in the formation of glucosamine (2-amino-2-deoxyglucopyranose), an aminodeoxysugar that occurs in combined form in chitin.	tmpzr1t_l9r_go_relaxed.owl	chitosamine biosynthetic process|glucosamine anabolism|glucosamine synthesis|glucosamine formation|glucosamine biosynthesis|chitosamine biosynthesis													biological_process											owl:Class	
GO:0006164	biolink:NamedThing	purine nucleotide biosynthetic process	The chemical reactions and pathways resulting in the formation of a purine nucleotide, a compound consisting of nucleoside (a purine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.	tmpzr1t_l9r_go_relaxed.owl	purine nucleotide formation|purine nucleotide biosynthesis|purine nucleotide synthesis|purine nucleotide anabolism				MetaCyc:DENOVOPURINE2-PWY									biological_process											owl:Class	
GO:1905352	biolink:NamedThing	ciliary necklace assembly	The aggregation, arrangement and bonding together of a set of components to form a ciliary necklace.	tmpzr1t_l9r_go_relaxed.owl	cilium necklace assembly|ciliary necklace formation|cilial necklace assembly|cilial necklace formation|cilium necklace formation							pr	2016-08-05T14:01:23Z					biological_process											owl:Class	
GO:0060676	biolink:NamedThing	ureteric bud formation	The developmental process pertaining to the initial formation of the ureteric bud from the Wolffian duct. This process begins when the bud protrudes from the duct and ends when it is a recognizable bud.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-06-02T01:47:23Z					biological_process											owl:Class	
GO:0072172	biolink:NamedThing	mesonephric tubule formation	The developmental process pertaining to the initial formation of a mesonephric tubule from unspecified parts. A mesonephric tubule is an epithelial tube that is part of the mesonephros.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-02-26T02:02:37Z					biological_process											owl:Class	
GO:0042755	biolink:NamedThing	eating behavior	The specific behavior of an organism relating to the intake of food, any substance (usually solid) that can be metabolized by an organism to give energy and build tissue.	tmpzr1t_l9r_go_relaxed.owl	eating behaviour													biological_process											owl:Class	
GO:0043477	biolink:NamedThing	pigment biosynthetic process involved in pigment accumulation	The chemical reactions and pathways resulting in the formation of a pigment, any general or particular coloring matter in living organisms, resulting in pigment accumulation.	tmpzr1t_l9r_go_relaxed.owl	pigment biosynthetic process during pigment accumulation													biological_process											owl:Class	
GO:0050173	biolink:NamedThing	phenylalanine adenylyltransferase activity	Catalysis of the reaction: L-phenylalanine + ATP = N-adenylyl-L-phenylalanine + diphosphate + 2 H(+).	tmpzr1t_l9r_go_relaxed.owl	ATP:L-phenylalanine adenylyltransferase activity|L-phenylalanine adenylyltransferase activity|ATP:phenylalanine adenylyltransferase activity				MetaCyc:PHENYLALANINE-ADENYLYLTRANSFERASE-RXN|RHEA:17189|EC:2.7.7.54|KEGG_REACTION:R00687									molecular_function											owl:Class	
GO:0031281	biolink:NamedThing	positive regulation of cyclase activity	Any process that activates or increases the activity of a cyclase.	tmpzr1t_l9r_go_relaxed.owl	upregulation of cyclase activity|up regulation of cyclase activity|activation of cyclase activity|up-regulation of cyclase activity|stimulation of cyclase activity													biological_process											owl:Class	
GO:0045915	biolink:NamedThing	positive regulation of catecholamine metabolic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving catecholamine.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of catecholamine metabolic process|positive regulation of catecholamine metabolism|activation of catecholamine metabolic process|up regulation of catecholamine metabolic process|upregulation of catecholamine metabolic process|stimulation of catecholamine metabolic process													biological_process											owl:Class	
GO:1990212	biolink:NamedThing	positive regulation by symbiont of ethylene levels in host	Any process in which an organism activates, maintains or increases the frequency, rate or extent of the ethylene levels in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl								ml	2013-10-09T19:03:10Z					biological_process											owl:Class	
GO:0052021	biolink:NamedThing	modulation by symbiont of ethylene levels in host	The alteration by an organism of the levels of ethylene in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	modulation by organism of ethylene levels in other organism involved in symbiotic interaction											GO:0052449		biological_process											owl:Class	
GO:0051139	biolink:NamedThing	metal ion:proton antiporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: metal ion(in) + H+(out) = metal ion(out) + H+(in).	tmpzr1t_l9r_go_relaxed.owl	metal ion:hydrogen antiporter activity				Reactome:R-HSA-435171									molecular_function											owl:Class	
GO:0097057	biolink:NamedThing	TRAF2-GSTP1 complex	A protein complex comprising tumor necrosis factor (TNF) receptor-associated factor 2 (TRAF2) and glutathione S-transferase pi 1 (GSTP1). This complex is thought to disrupt the TNF signaling cascade, thus down-regulating inflammatory responses.	tmpzr1t_l9r_go_relaxed.owl								pr	2011-05-26T10:35:45Z					cellular_component											owl:Class	
GO:0060823	biolink:NamedThing	canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation	The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes that contributes to the formation of the neural plate anterior/posterior pattern.	tmpzr1t_l9r_go_relaxed.owl	canonical Wnt-activated signaling pathway involved in neural plate anterior/posterior pattern formation|canonical Wnt receptor signalling pathway involved in neural plate anterior/posterior pattern formation|canonical Wnt receptor signaling pathway involved in neural plate anterior/posterior pattern formation|Wnt receptor signaling pathway through beta-catenin involved in neural plate anterior/posterior pattern formation							dph	2009-08-11T01:22:42Z					biological_process											owl:Class	
GO:0072570	biolink:NamedThing	ADP-D-ribose binding	Binding to ADP-D-ribose, an ADP-aldose having ribose as the aldose fragment.	tmpzr1t_l9r_go_relaxed.owl	ADP-ribose binding							mah	2011-01-31T02:37:30Z					molecular_function											owl:Class	
GO:0045585	biolink:NamedThing	positive regulation of cytotoxic T cell differentiation	Any process that activates or increases the frequency, rate or extent of cytotoxic T cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	activation of cytotoxic T cell differentiation|positive regulation of cytotoxic T-lymphocyte differentiation|positive regulation of cytotoxic T lymphocyte differentiation|stimulation of cytotoxic T cell differentiation|upregulation of cytotoxic T cell differentiation|positive regulation of cytotoxic T-cell differentiation|positive regulation of cytotoxic T cell development|up regulation of cytotoxic T cell differentiation|up-regulation of cytotoxic T cell differentiation					Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.								biological_process											owl:Class	
GO:0043421	biolink:NamedThing	anthranilate catabolic process	The chemical reactions and pathways resulting in the breakdown of anthranilate (2-aminobenzoate).	tmpzr1t_l9r_go_relaxed.owl	2-aminobenzoate catabolism|ortho-aminobenzoic acid catabolic process|anthranilate breakdown|2-aminobenzoate breakdown|anthranilate degradation|2-aminobenzoate degradation|anthranilate catabolism|2-aminobenzoate catabolic process|anthranilic acid catabolism|ortho-aminobenzoic acid catabolism|anthranilic acid catabolic process				MetaCyc:2AMINOBENZDEG-PWY							GO:0019259		biological_process											owl:Class	
GO:0047809	biolink:NamedThing	D-2-hydroxy-acid dehydrogenase activity	Catalysis of the reaction: (R)-lactate + A = AH(2) + pyruvate.	tmpzr1t_l9r_go_relaxed.owl	2-hydroxy acid dehydrogenase activity|(R)-2-hydroxy-acid:(acceptor) 2-oxidoreductase activity				RHEA:15089|EC:1.1.99.6|MetaCyc:D-2-HYDROXY-ACID-DEHYDROGENASE-RXN|KEGG_REACTION:R00297									molecular_function											owl:Class	
GO:0050167	biolink:NamedThing	pantothenoylcysteine decarboxylase activity	Catalysis of the reaction: N-[(R)-pantothenoyl]-L-cysteine + H(+) = (R)-pantetheine + CO(2).	tmpzr1t_l9r_go_relaxed.owl	N-((R)-pantothenoyl)-L-cysteine carboxy-lyase activity|N-[(R)-pantothenoyl]-L-cysteine carboxy-lyase (pantetheine-forming)|pantothenylcysteine decarboxylase activity|N-[(R)-pantothenoyl]-L-cysteine carboxy-lyase activity				RHEA:15077|KEGG_REACTION:R02972|MetaCyc:PANTOTHENOYLCYSTEINE-DECARBOXYLASE-RXN|EC:4.1.1.30									molecular_function											owl:Class	
GO:0072060	biolink:NamedThing	outer medullary collecting duct development	The process whose specific outcome is the progression of the outer medullary collecting duct over time, from its formation to the mature structure. The outer medullary collecting duct is the portion of the collecting duct that lies in the renal outer medulla.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-01-25T04:08:18Z					biological_process											owl:Class	
GO:1904887	biolink:NamedThing	Wnt signalosome assembly	The aggregation, arrangement and bonding together of a set of components to form a Wnt signalosome.	tmpzr1t_l9r_go_relaxed.owl	Wnt signalosome complex formation|Wnt signalosome complex assembly|Wnt-LRP5/6 signalosome formation|LRP6 signalosome formation|LRP5/6 signalosome assembly|LRP5/6 signalosome formation|Wnt-LRP5/6 signalosome assembly|LRP6 signalosome assembly|Wnt signalosome formation							bf	2016-01-05T15:34:36Z					biological_process											owl:Class	
GO:0043761	biolink:NamedThing	archaetidylserine synthase activity	Catalysis of the reaction: CDP-digeranylgeranylglycerol + L-serine = archaetidylserine + CMP.	tmpzr1t_l9r_go_relaxed.owl	CDP-2,3-di-O-geranylgeranyl-sn-glycerol inositol 1-archaetidyltransferase activity|CDP-2,3-di-O-geranylgeranyl-sn-glycerol:l-serine O-archaetidyltransferase activity				EC:2.7.8.38									molecular_function											owl:Class	
GO:0005872	biolink:NamedThing	minus-end kinesin complex	Any complex that includes a dimer of molecules from the kinesin superfamily and any associated proteins, and moves towards the minus end of a microtubule.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0005871	biolink:NamedThing	kinesin complex	Any complex that includes a dimer of molecules from the kinesin superfamily, a group of related proteins that contain an extended region of predicted alpha-helical coiled coil in the main chain that likely produces dimerization. The native complexes of several kinesin family members have also been shown to contain additional peptides, often designated light chains as all of the noncatalytic subunits that are currently known are smaller than the chain that contains the motor unit. Kinesin complexes generally possess a force-generating enzymatic activity, or motor, which converts the free energy of the gamma phosphate bond of ATP into mechanical work.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0051591	biolink:NamedThing	response to cAMP	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate) stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to adenosine 3',5'-cyclophosphate|response to 3',5'-cAMP|response to cyclic AMP|response to 3',5' cAMP													biological_process											owl:Class	
GO:0050945	biolink:NamedThing	positive regulation of iridophore differentiation	Any process that activates or increases the frequency, rate or extent of iridophore differentiation.	tmpzr1t_l9r_go_relaxed.owl	upregulation of iridophore differentiation|stimulation of iridophore differentiation|up-regulation of iridophore differentiation|up regulation of iridophore differentiation|activation of iridophore differentiation													biological_process											owl:Class	
GO:0034174	biolink:NamedThing	toll-like receptor 12 signaling pathway	Any series of molecular signals generated as a consequence of binding to toll-like receptor 12.	tmpzr1t_l9r_go_relaxed.owl	TLR12 signaling pathway|toll-like receptor 12 signalling pathway													biological_process											owl:Class	
GO:0070421	biolink:NamedThing	DNA ligase III-XRCC1 complex	A protein complex that contains DNA ligase III and XRCC1, and is involved in base excision repair.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0010965	biolink:NamedThing	regulation of mitotic sister chromatid separation	Any process that modulates the frequency, rate or extent of mitotic sister chromatid separation. Mitotic sister chromatid separation is the process in which sister chromatids are physically detached from each other during mitosis.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-05-20T11:39:07Z					biological_process											owl:Class	
GO:0016475	biolink:NamedThing	detection of nuclear:cytoplasmic ratio	The process in which the size of the nucleus with respect to its cytoplasm is sensed by a cell.	tmpzr1t_l9r_go_relaxed.owl	interpretation of nuclear:cytoplasmic ratio|sensing of nuclear:cytoplasmic ratio													biological_process											owl:Class	
GO:0009726	biolink:NamedThing	detection of endogenous stimulus	The series of events in which an endogenous stimulus is received by a cell and converted into a molecular signal.	tmpzr1t_l9r_go_relaxed.owl	perception of endogenous stimulus													biological_process											owl:Class	
GO:0002562	biolink:NamedThing	somatic diversification of immune receptors via germline recombination within a single locus	The process in which immune receptor genes are diversified through recombination of the germline genetic elements within a single genetic locus.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0060468	biolink:NamedThing	prevention of polyspermy	The negative regulation of fertilization process that takes place as part of egg activation, ensuring that only a single sperm fertilizes the egg.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of fertilization involved in egg activation|polyspermy block													biological_process											owl:Class	
GO:0060467	biolink:NamedThing	negative regulation of fertilization	Any process that decreases the rate, frequency or extent of fertilization. Fertilization is the union of gametes of opposite sexes during the process of sexual reproduction to form a zygote. It involves the fusion of the gametic nuclei (karyogamy) and cytoplasm (plasmogamy).	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0019083	biolink:NamedThing	viral transcription	The process by which a viral genome, or part of a viral genome, is transcribed within the host cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0015837	biolink:NamedThing	amine transport	The directed movement of amines, including polyamines, organic compounds containing one or more amino groups, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	amine/polyamine transport													biological_process											owl:Class	
GO:1900977	biolink:NamedThing	regulation of tatiopterin metabolic process	Any process that modulates the frequency, rate or extent of tatiopterin metabolic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of tatiopterin metabolism							tt	2012-06-14T04:03:06Z					biological_process											owl:Class	
GO:0102991	biolink:NamedThing	myristoyl-CoA hydrolase activity	Catalysis of the reaction: myristoyl-CoA + H2O <=> H+ + tetradecanoate + coenzyme A.	tmpzr1t_l9r_go_relaxed.owl					EC:3.1.2.2|RHEA:40119|MetaCyc:RXN-9626									molecular_function											owl:Class	
GO:0110166	biolink:NamedThing	DNA synthesis involved in mitochondrial DNA replication	Any DNA biosynthetic process that is involved in mitochondrial DNA replication.	tmpzr1t_l9r_go_relaxed.owl	DNA biosynthetic process involved in mitochondrial DNA replication	https://github.com/geneontology/go-ontology/issues/17716						kmv	2020-03-18T13:30:39Z					biological_process											owl:Class	
GO:0047534	biolink:NamedThing	2-acetolactate mutase activity	Catalysis of the reaction: 2-acetolactate = 3-hydroxy-3-methyl-2-oxobutanoate.	tmpzr1t_l9r_go_relaxed.owl	acetohydroxy acid isomerase activity|acetolactate mutase activity|2-acetolactate methylmutase activity				RHEA:16361|EC:5.4.99.3|MetaCyc:2-ACETOLACTATE-MUTASE-RXN									molecular_function											owl:Class	
GO:0060820	biolink:NamedThing	inactivation of X chromosome by heterochromatin assembly	Compensating for the two-fold variation in X-chromosome:autosome ratios between sexes by a global inactivation of all, or most of, the genes on one of the X-chromosomes in the XX sex by the mechanism of heterochromatin formation.	tmpzr1t_l9r_go_relaxed.owl	inactivation of X chromosome by heterochromatin formation							dph	2009-08-11T10:58:06Z					biological_process											owl:Class	
GO:1902221	biolink:NamedThing	erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process	The chemical reactions and pathways involving erythrose 4-phosphate/phosphoenolpyruvate family amino acid.	tmpzr1t_l9r_go_relaxed.owl	erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolism							pr	2013-06-13T10:37:38Z					biological_process											owl:Class	
GO:2000589	biolink:NamedThing	regulation of metanephric mesenchymal cell migration	Any process that modulates the frequency, rate or extent of metanephric mesenchymal cell migration.	tmpzr1t_l9r_go_relaxed.owl	regulation of metanephric mesenchyme chemotaxis							bf	2011-04-07T03:29:43Z					biological_process											owl:Class	
GO:0006036	biolink:NamedThing	cuticle chitin catabolic process	The chemical reactions and pathways resulting in the breakdown of cuticle chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues, found in cuticles.	tmpzr1t_l9r_go_relaxed.owl	cuticle chitin degradation|cuticle chitin breakdown|cuticle chitin catabolism													biological_process											owl:Class	
GO:0006034	biolink:NamedThing	cuticle chitin metabolic process	The chemical reactions and pathways involving cuticle chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues, found in cuticles.	tmpzr1t_l9r_go_relaxed.owl	cuticle chitin metabolism													biological_process											owl:Class	
GO:0055118	biolink:NamedThing	negative regulation of cardiac muscle contraction	Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle contraction.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0018561	biolink:NamedThing	2'-aminobiphenyl-2,3-diol 1,2-dioxygenase activity	Catalysis of the reaction: 2'-aminobiphenyl-2,3-diol + O2 = H+ + 2-hydroxy-6-oxo-(2'-aminophenyl)-hexa-2,4-dienoate.	tmpzr1t_l9r_go_relaxed.owl					EC:1.13.11.-|UM-BBD_reactionID:r0457									molecular_function											owl:Class	
GO:0097465	biolink:NamedThing	somatic spine	Spine emanating from the cell soma of a neuron.	tmpzr1t_l9r_go_relaxed.owl					NIF_Subcellular:sao2048514053			pr	2012-12-21T08:02:37Z					cellular_component											owl:Class	
GO:0120306	biolink:NamedThing	cellular response to actin cytoskeletal stress	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of perturbations or damage to the actin cytoskeleton.	tmpzr1t_l9r_go_relaxed.owl	cellular response to latrunculin A|cellular response to actin cytoskeleton stress|cellular response to latrunculin B|response to latrunculin B|response to latrunculin A	https://github.com/geneontology/go-ontology/issues/20189						krc	2021-02-12T21:44:37Z			GO:1903956|GO:1904805|GO:1904804|GO:1903957		biological_process											owl:Class	
GO:0014827	biolink:NamedThing	intestine smooth muscle contraction	A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the intestine. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The intestine is the section of the alimentary canal from the stomach to the anal canal. It includes the large intestine and small intestine.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0010812	biolink:NamedThing	negative regulation of cell-substrate adhesion	Any process that decreases the frequency, rate or extent of cell-substrate adhesion. Cell-substrate adhesion is the attachment of a cell to the underlying substrate via adhesion molecules.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0019107	biolink:NamedThing	myristoyltransferase activity	Catalysis of the transfer of a myristoyl (CH3-[CH2]12-CO-) group to an acceptor molecule.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-162914|Reactome:R-HSA-141367									molecular_function											owl:Class	
GO:0043537	biolink:NamedThing	negative regulation of blood vessel endothelial cell migration	Any process that stops, prevents, or reduces the frequency, rate or extent of the migration of the endothelial cells of blood vessels.	tmpzr1t_l9r_go_relaxed.owl	down regulation of blood vessel endothelial cell migration|downregulation of blood vessel endothelial cell migration|inhibition of blood vessel endothelial cell migration|down-regulation of blood vessel endothelial cell migration													biological_process											owl:Class	
GO:0010596	biolink:NamedThing	negative regulation of endothelial cell migration	Any process that decreases the rate, frequency, or extent of the orderly movement of an endothelial cell into the extracellular matrix to form an endothelium.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1900359	biolink:NamedThing	positive regulation of nigerotriose transport	Any process that activates or increases the frequency, rate or extent of nigerotriose transport.	tmpzr1t_l9r_go_relaxed.owl	upregulation of nigerotriose transport|activation of nigerotriose transport|up-regulation of nigerotriose transport|up regulation of nigerotriose transport							tt	2012-04-06T02:18:29Z					biological_process											owl:Class	
GO:0021845	biolink:NamedThing	neurotransmitter-mediated guidance of interneurons involved in substrate-independent cerebral cortex tangential migration	The response of migrating interneurons to neurotransmitters that alter electrical activity in cells in calcium dependent manner.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0150102	biolink:NamedThing	negative regulation of monocyte activation	Any process that stops, prevents or reduces the frequency, rate or extent of monocyte activation.	tmpzr1t_l9r_go_relaxed.owl	repression of monocyte activation							bc	2019-04-26T20:01:24Z					biological_process											owl:Class	
GO:0102348	biolink:NamedThing	trans-docosan-2-enoyl-CoA reductase activity	Catalysis of the reaction: behenoyl-CoA + NADP <=> trans-2-docosenoyl-CoA + NADPH + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-13307									molecular_function											owl:Class	
GO:1903378	biolink:NamedThing	positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway	Any process that activates or increases the frequency, rate or extent of oxidative stress-induced neuron intrinsic apoptotic signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	up regulation of neuron intrinsic apoptotic signaling pathway in response to oxidative stress|upregulation of neuron intrinsic apoptotic signaling pathway in response to oxidative stress|up-regulation of neuron apoptosis in response to oxidative stress|positive regulation of neuron intrinsic apoptotic signaling pathway in response to oxidative stress|positive regulation of neuron apoptosis in response to oxidative stress|activation of neuron apoptosis in response to oxidative stress|upregulation of neuron apoptosis in response to oxidative stress|up-regulation of neuron intrinsic apoptotic signaling pathway in response to oxidative stress|up regulation of neuron apoptosis in response to oxidative stress|activation of neuron intrinsic apoptotic signaling pathway in response to oxidative stress							bf	2014-08-26T13:03:36Z					biological_process											owl:Class	
GO:0010185	biolink:NamedThing	regulation of cellular defense response	Any process that modulates the frequency, rate or extent of cellular defense response.	tmpzr1t_l9r_go_relaxed.owl	regulation of cellular defence response													biological_process											owl:Class	
GO:0033996	biolink:NamedThing	levan fructotransferase (DFA-IV-forming) activity	Catalysis of the reaction: beta-D-fructopyranosyl-(2->6)-[D-fructofuranosyl-(2->6)]n-D-fructofuranoside = beta-D-fructopyranosyl-(2->6)-[D-fructofuranosyl-(2->6)](n-1)-D-fructofuranoside + di-beta-D-fructofuranose 2,6':2',6-dianhydride. This reaction is the production of di-beta-D-fructofuranose 2,6':2',6-dianhydride (DFA IV) by successively eliminating the diminishing (2->6)-beta-D-fructan (levan) chain from the terminal D-fructosyl-D-fructosyl disaccharide.	tmpzr1t_l9r_go_relaxed.owl	2,6-beta-D-fructan lyase (di-beta-D-fructofuranose-2,6':2',6-dianhydride-forming) activity|2,6-beta-D-fructan D-fructosyl-D-fructosyltransferase (forming di-beta-D-fructofuranose 2,6':2',6-dianhydride) activity|levan fructotransferase activity				MetaCyc:4.2.2.16-RXN|EC:4.2.2.16									molecular_function											owl:Class	
GO:0036084	biolink:NamedThing	GDP-fucose import into endoplasmic reticulum lumen	The directed movement of GDP-fucose into the endoplasmic reticulum lumen. GDP-fucose is a substance composed of fucose in glycosidic linkage with guanosine diphosphate.	tmpzr1t_l9r_go_relaxed.owl	GDP-fucose transport across endoplasmic reticulum membrane|GDP-fucose transport into endoplasmic reticulum lumen|GDP-fucose import into endoplasmic reticulum							bf	2011-12-21T01:45:11Z					biological_process											owl:Class	
GO:0002567	biolink:NamedThing	somatic diversification of FREP-based immune receptors	The process that results in the generation of sequence diversity of the FREP-based immune receptors of snails.	tmpzr1t_l9r_go_relaxed.owl						Note that this type of immune receptor has been found in snails (Pulmonata, ncbi_axonomy_id:6519), but may also be seen in other species.								biological_process											owl:Class	
GO:0002200	biolink:NamedThing	somatic diversification of immune receptors	The somatic process allowing for the production of immune receptors whose specificity is not encoded in the germline genomic sequences.	tmpzr1t_l9r_go_relaxed.owl						Note that this process covers somatic recombination, gene conversion, hypermutation, N-region addition, and alternate splicing processes of immune receptor diversification.								biological_process											owl:Class	
GO:0009729	biolink:NamedThing	detection of brassinosteroid stimulus	The series of events in which a brassinosteroid stimulus is received by a cell and converted into a molecular signal.	tmpzr1t_l9r_go_relaxed.owl	perception of brassinosteroid stimulus													biological_process											owl:Class	
GO:0046972	biolink:NamedThing	histone acetyltransferase activity (H4-K16 specific)	Catalysis of the reaction: acetyl-CoA + histone H4 L-lysine (position 16) = CoA + histone H4 N6-acetyl-L-lysine (position 16). This reaction represents the addition of an acetyl group to the lysine at position 16 of histone H4.	tmpzr1t_l9r_go_relaxed.owl	histone lysine acetyltransferase activity (H4-K16 specific)													molecular_function											owl:Class	
GO:0010485	biolink:NamedThing	H4 histone acetyltransferase activity	Catalysis of the reaction: acetyl-CoA + histone H4 = CoA + acetyl-histone H4.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0061599	biolink:NamedThing	molybdopterin molybdotransferase activity	Catalysis of the reaction adenylyl-molybdopterin + molybdate = molybdenum cofactor + AMP.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-947531|EC:2.10.1.1|RHEA:35047			dph	2014-02-10T14:30:31Z					molecular_function											owl:Class	
GO:1901905	biolink:NamedThing	response to tamsulosin	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tamsulosin stimulus.	tmpzr1t_l9r_go_relaxed.owl								hp	2013-02-13T10:14:41Z					biological_process											owl:Class	
GO:0030550	biolink:NamedThing	acetylcholine receptor inhibitor activity	Binds to and stops, prevents or reduces the activity of an acetylcholine receptor.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0052908	biolink:NamedThing	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity	Catalysis of the reaction: 4 S-adenosyl-L-methionine + adenine(1518)/adenine(1519) in 16S rRNA = 4 S-adenosyl-L-homocysteine + N(6)-dimethyladenine(1518)/N(6)-dimethyladenine(1519) in 16S rRNA.	tmpzr1t_l9r_go_relaxed.owl	S-adenosylmethionine-6-N',N'-adenosyl (rRNA) dimethyltransferase activity	https://github.com/geneontology/go-ontology/issues/14459			RHEA:19609|EC:2.1.1.182|MetaCyc:RXN-11633									molecular_function											owl:Class	
GO:0043309	biolink:NamedThing	regulation of eosinophil degranulation	Any process that modulates the frequency, rate, or extent of eosinophil degranulation.	tmpzr1t_l9r_go_relaxed.owl	regulation of eosinophil granule exocytosis													biological_process											owl:Class	
GO:0099169	biolink:NamedThing	anchored component of postsynaptic specialization membrane of symmetric synapse	The component of the postsynaptic specialization membrane of a symmetric synapse consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping.	tmpzr1t_l9r_go_relaxed.owl								dos	2017-09-10T12:01:53Z					cellular_component											owl:Class	
GO:0035853	biolink:NamedThing	chromosome passenger complex localization to spindle midzone	A cellular protein complex localization that acts on a chromosome passenger complex; as a result, the complex is transported to, or maintained in, a specific location at the spindle midzone. A chromosome passenger complex is a protein complex that contains the BIR-domain-containing protein Survivin, Aurora B kinase, INCENP and Borealin, and coordinates various events based on its location to different structures during the course of mitosis. The spindle midzone is the area in the center of the spindle where the spindle microtubules from opposite poles overlap.	tmpzr1t_l9r_go_relaxed.owl	CPC complex localization to spindle midzone|chromosomal passenger complex localization to spindle midzone|CPC localization to spindle midzone|chromosome passenger complex localization to central spindle|chromosome passenger complex localisation to spindle midzone|chromosome passenger complex localization to spindle equator							bf	2011-05-13T01:19:51Z					biological_process											owl:Class	
GO:0046926	biolink:NamedThing	peptide cross-linking via 2-(S-L-cysteinyl)-D-allo-threonine	The post-translational cross-linking of a cysteine residue to an L-threonine residue to form 2-(S-L-cysteinyl)-D-allo-threonine.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0342									biological_process											owl:Class	
GO:0061325	biolink:NamedThing	cell proliferation involved in outflow tract morphogenesis	The multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to the shaping of the outflow tract.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-09-28T09:29:30Z					biological_process											owl:Class	
GO:0047488	biolink:NamedThing	heparin lyase activity	Catalysis of the eliminative cleavage of polysaccharides containing 1,4-linked D-glucuronate or L-iduronate residues and 1,4-alpha-linked 2-sulfoamino-2-deoxy-6-sulfo-D-glucose residues to give oligosaccharides with terminal 4-deoxy-alpha-D-gluc-4-enuronosyl groups at their nonreducing ends.	tmpzr1t_l9r_go_relaxed.owl	heparan sulfate lyase activity|heparinase activity|heparin eliminase activity				EC:4.2.2.7|MetaCyc:4.2.2.7-RXN									molecular_function											owl:Class	
GO:0033611	biolink:NamedThing	oxalate catabolic process	The chemical reactions and pathways resulting in the breakdown of oxalate, the organic acid ethanedioate.	tmpzr1t_l9r_go_relaxed.owl	oxalate breakdown|oxalate degradation|oxalate catabolism|ethanedioic acid catabolic process|oxalic acid catabolic process|ethanedioate catabolic process													biological_process											owl:Class	
GO:1901810	biolink:NamedThing	beta-carotene metabolic process	The chemical reactions and pathways involving beta-carotene.	tmpzr1t_l9r_go_relaxed.owl	beta-carotene metabolism							yaf	2013-01-22T10:30:23Z					biological_process											owl:Class	
GO:0038022	biolink:NamedThing	G protein-coupled olfactory receptor activity	Combining with an odorant and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.	tmpzr1t_l9r_go_relaxed.owl	olfactory receptor activity, G-protein coupled|odorant receptor activity, G-protein coupled|G-protein coupled odorant receptor activity|G-protein coupled olfactory receptor activity							bf	2011-07-01T11:23:51Z					molecular_function											owl:Class	
GO:0097730	biolink:NamedThing	non-motile cilium	A cilium which may have a variable array of axonemal microtubules but does not contain molecular motors.	tmpzr1t_l9r_go_relaxed.owl	sensory cilium|immotile cilium|nonmotile primary cilium|immotile primary cilium|nonmotile primary cilia|nonmotile cilium							pr	2016-09-29T14:02:11Z			GO:0031513		cellular_component											owl:Class	
GO:2000936	biolink:NamedThing	regulation of cellotriose catabolic process	Any process that modulates the frequency, rate or extent of cellotriose catabolic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of cellotriose catabolism							tt	2011-08-01T12:45:26Z					biological_process											owl:Class	
GO:0016692	biolink:NamedThing	NADH peroxidase activity	Catalysis of the reaction: H(2)O(2) + H(+) + NADH = 2 H(2)O + NAD(+).	tmpzr1t_l9r_go_relaxed.owl	nicotinamide adenine dinucleotide peroxidase activity|NADH-peroxidase activity|NAD peroxidase activity|NADH:hydrogen-peroxide oxidoreductase activity|diphosphopyridine nucleotide peroxidase activity|DPNH peroxidase activity				MetaCyc:NADH-PEROXIDASE-RXN|EC:1.11.1.1|KEGG_REACTION:R00090|RHEA:18509									molecular_function											owl:Class	
GO:1901694	biolink:NamedThing	positive regulation of compound eye retinal cell apoptotic process	Any process that activates or increases the frequency, rate or extent of compound eye retinal cell apoptotic process.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of compound eye retinal cell apoptotic process|induction of compound eye retinal cell programmed cell death|activation of compound eye retinal cell apoptotic process|up regulation of compound eye retinal cell apoptotic process|upregulation of compound eye retinal cell apoptotic process							pr	2012-12-12T10:28:45Z			GO:0046675		biological_process											owl:Class	
GO:1901692	biolink:NamedThing	regulation of compound eye retinal cell apoptotic process	Any process that modulates the frequency, rate or extent of compound eye retinal cell apoptotic process.	tmpzr1t_l9r_go_relaxed.owl								pr	2012-12-12T10:28:35Z					biological_process											owl:Class	
GO:0042740	biolink:NamedThing	exogenous antibiotic catabolic process	The chemical reactions and pathways resulting in the breakdown of an antibiotic that has originated externally to the cell or organism.	tmpzr1t_l9r_go_relaxed.owl	exogenous antibiotic degradation|exogenous antibiotic breakdown|exogenous antibiotic catabolism													biological_process											owl:Class	
GO:0008445	biolink:NamedThing	D-aspartate oxidase activity	Catalysis of the reaction: D-aspartate + H2O + O2 = oxaloacetate + NH3 + hydrogen peroxide.	tmpzr1t_l9r_go_relaxed.owl	D-aspartate:oxygen oxidoreductase (deaminating)|D-aspartic oxidase activity|aspartic oxidase activity				EC:1.4.3.1|RHEA:12512|MetaCyc:D-ASPARTATE-OXIDASE-RXN|Reactome:R-HSA-6810076									molecular_function											owl:Class	
GO:0075030	biolink:NamedThing	modulation of formation of symbiont germ tube hook structure for appressorium development	Any process that modulates the frequency, rate or extent of symbiont germ tube hook structure formation.	tmpzr1t_l9r_go_relaxed.owl	modulation of germ tube tip of symbiont on or near the exterior of host|regulation of formation of symbiont germ tube hook structure on or near host|modulation of symbiont germ tube hook structure formation on or near host													biological_process											owl:Class	
GO:0005893	biolink:NamedThing	interleukin-2 receptor complex	A protein complex that binds interleukin-2; comprises alpha, beta, and gamma subunits.	tmpzr1t_l9r_go_relaxed.owl	IL-2 receptor complex													cellular_component											owl:Class	
GO:0075292	biolink:NamedThing	negative regulation of aplanospore formation	Any process that stops, prevents, or reduces the frequency, rate or extent of aplanospore formation, a process in which a nonmotile, asexual spore is formed within a cell in certain algae and fungi (commonly in the Phycomycetes), the wall of aplanospore is distinct from that of the parent cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0006858	biolink:NamedThing	extracellular transport	The transport of substances that occurs outside cells.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0045748	biolink:NamedThing	positive regulation of R8 cell spacing in compound eye	Any process that activates or enforces the correct R8 cell spacing in a compound eye.	tmpzr1t_l9r_go_relaxed.owl	activation of R8 spacing|up regulation of R8 spacing|up-regulation of R8 spacing|upregulation of R8 spacing|stimulation of R8 spacing|positive regulation of R8 spacing													biological_process											owl:Class	
GO:0000934	biolink:NamedThing	porous cell septum	A septum or cross wall which does not entirely span the space between two portions of cell wall and may contain a specialized central pore structure. A porous septum allows the movement of organelles and/or cytoplasm between compartments.	tmpzr1t_l9r_go_relaxed.owl	porous septum													cellular_component											owl:Class	
GO:0030428	biolink:NamedThing	cell septum	A structure composed of peptidoglycan and often chitin in addition to other materials. It usually forms perpendicular to the long axis of a cell or hypha and grows centripetally from the cell wall to the center of the cell and often functions in the compartmentalization of a cell into two daughter cells.	tmpzr1t_l9r_go_relaxed.owl	cross wall|septum													cellular_component											owl:Class	
GO:0043530	biolink:NamedThing	adenosine 5'-monophosphoramidase activity	Catalysis of the reaction: adenosine 5'-monophosphoramidate + H2O = AMP + NH4+. Other substrates include AMP-morpholidate, AMP-N-alanine methyl ester and AMP-alpha-acetyl lysine methyl ester.	tmpzr1t_l9r_go_relaxed.owl	adenosine 5' monophosphoramidase activity|adenosine 5'-monophosphoramidate hydrolase activity													molecular_function											owl:Class	
GO:0043250	biolink:NamedThing	sodium-dependent organic anion transmembrane transporter activity	Enables the transfer of organic anions from one side of a membrane to the other, in a sodium dependent manner.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1903911	biolink:NamedThing	positive regulation of receptor clustering	Any process that activates or increases the frequency, rate or extent of receptor clustering.	tmpzr1t_l9r_go_relaxed.owl	upregulation of receptor clustering|up-regulation of receptor clustering|up regulation of receptor clustering|activation of receptor clustering							als	2015-02-09T10:56:51Z					biological_process											owl:Class	
GO:1902731	biolink:NamedThing	negative regulation of chondrocyte proliferation	Any process that stops, prevents, or reduces the frequency, rate or extent of the multiplication or reproduction of chondrocytes by cell division, resulting in the expansion of their population. A chondrocyte is a polymorphic cell that forms cartilage.	tmpzr1t_l9r_go_relaxed.owl	down regulation of cartilage cell proliferation|negative regulation of chondrocyte cell proliferation|down-regulation of chondrocyte proliferation|down regulation of chondrocyte cell proliferation|down regulation of chondrocyte proliferation|down-regulation of chondrocyte cell proliferation|down-regulation of cartilage cell proliferation|inhibition of chondrocyte proliferation|inhibition of chondrocyte cell proliferation|negative regulation of cartilage cell proliferation|downregulation of chondrocyte cell proliferation|downregulation of chondrocyte proliferation|inhibition of cartilage cell proliferation|downregulation of cartilage cell proliferation							mr	2014-02-24T16:11:02Z					biological_process											owl:Class	
GO:0075114	biolink:NamedThing	suppression by symbiont of host transmembrane receptor-mediated signal transduction	Any process in which the symbiont stops, prevents, or reduces the frequency, rate or extent of transmembrane receptor-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	negative regulation by symbiont of host transmembrane receptor-mediated signal transduction					Note that this term is used to annotate gene products of the symbiont. To annotate host gene products, consider the biological process term "negative regulation by host of symbiont transmembrane receptor-mediated signal transduction ; GO:0075083".								biological_process											owl:Class	
GO:1990146	biolink:NamedThing	protein localization to rhabdomere	A process in which a protein is transported to, or maintained in, a location within a rhabdomere.	tmpzr1t_l9r_go_relaxed.owl								sart	2013-07-25T11:24:49Z					biological_process											owl:Class	
GO:1905050	biolink:NamedThing	positive regulation of metallopeptidase activity	Any process that activates or increases the frequency, rate or extent of metallopeptidase activity.	tmpzr1t_l9r_go_relaxed.owl	upregulation of metalloproteinase activity|upregulation of metalloprotease activity|positive regulation of metalloproteinase activity|activation of metalloprotease activity|activation of metalloproteinase activity|activation of metallopeptidase activity|positive regulation of metalloprotease activity|up regulation of metalloproteinase activity|up regulation of metallopeptidase activity|up regulation of metalloprotease activity|up-regulation of metallopeptidase activity|up-regulation of metalloproteinase activity|up-regulation of metalloprotease activity|upregulation of metallopeptidase activity							mm2	2016-03-15T16:44:46Z					biological_process											owl:Class	
GO:0014065	biolink:NamedThing	phosphatidylinositol 3-kinase signaling	A series of reactions within the signal-receiving cell, mediated by the intracellular phosphatidylinositol 3-kinase (PI3K). Many cell surface receptor linked signaling pathways signal through PI3K to regulate numerous cellular functions.	tmpzr1t_l9r_go_relaxed.owl	PI3K signal transduction|PI3K cascade|PI 3-kinase cascade|phosphatidylinositol 3-kinase signal transduction|PI3K signaling|phosphoinositide 3-kinase cascade|phosphatidylinositol 3-kinase cascade													biological_process											owl:Class	
GO:0048015	biolink:NamedThing	phosphatidylinositol-mediated signaling	A series of molecular signals in which a cell uses a phosphatidylinositol-mediated signaling to convert a signal into a response. Phosphatidylinositols include phosphatidylinositol (PtdIns) and its phosphorylated derivatives.	tmpzr1t_l9r_go_relaxed.owl	phosphatidylinositol-mediated signal transduction|phosphatidylinositol-mediated signalling|phosphoinositide-mediated signaling|phosphoinositide-mediated signalling|inositol phospholipid-mediated signaling													biological_process											owl:Class	
GO:0097078	biolink:NamedThing	FAL1-SGD1 complex	A protein complex involved in the 18S rRNA biogenesis. In S. cerevisiae this complex consists of Fal1p and Sgd1p and in humans this complex consists of NOM1 and eIF4AIII subunits.	tmpzr1t_l9r_go_relaxed.owl								pr	2011-06-17T09:59:10Z					cellular_component											owl:Class	
GO:0060782	biolink:NamedThing	regulation of mesenchymal cell proliferation involved in prostate gland development	Any process that modulates the frequency, rate or extent of mesenchymal cell proliferation that contributes to the progression of the prostate gland over time. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-07-28T11:54:20Z					biological_process											owl:Class	
GO:0030083	biolink:NamedThing	PSI associated light-harvesting complex I, LHCIa subcomplex	A pigment protein complex that forms part of the photosystem I associated light-harvesting complex I; contains two proteins (usually about 24 and 21.5 kDa); has a fluorescence maximum between 680 and 690 nm.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0009518	biolink:NamedThing	PSI associated light-harvesting complex I	Protein-pigment complex associated with photosystem I.	tmpzr1t_l9r_go_relaxed.owl	LHCI													cellular_component											owl:Class	
GO:0045013	biolink:NamedThing	carbon catabolite repression of transcription	A transcription regulation process in which the presence of one carbon source leads to a decrease in the frequency, rate, or extent of transcription of specific genes involved in the metabolism of other carbon sources. Carbon catabolite repression is a mechanism of genetic regulation which the accumulation of catabolites of one substance in the cell represses the formation of enzymes that contribute to the catabolism of other substances.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of transcription by carbon catabolites|carbon catabolite repression													biological_process											owl:Class	
GO:0002940	biolink:NamedThing	tRNA N2-guanine methylation	The process whereby a guanine in a tRNA is methylated at the N2 position of guanine.	tmpzr1t_l9r_go_relaxed.owl	tRNA m2-guanine biosynthesis							hjd	2012-11-09T16:23:41Z					biological_process											owl:Class	
GO:0002299	biolink:NamedThing	alpha-beta intraepithelial T cell differentiation	The process in which a precursor cell type acquires the specialized features of an alpha-beta intraepithelial T cell. Intraepithelial T cells are found among epithelial cells in mucosal areas and have distinct phenotypes and developmental pathways.	tmpzr1t_l9r_go_relaxed.owl	alpha-beta intraepithelial T lymphocyte differentiation|alpha-beta intraepithelial T cell development|alpha-beta intraepithelial T-lymphocyte differentiation|alpha-beta intraepithelial T-cell differentiation					Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.								biological_process											owl:Class	
GO:0097045	biolink:NamedThing	phosphatidylserine exposure on blood platelet	A phospholipid scrambling process that results in the appearance of phosphatidylserine on the surface of activated blood platelets, and triggers the clotting system.	tmpzr1t_l9r_go_relaxed.owl								pr	2011-04-20T12:54:35Z					biological_process											owl:Class	
GO:1990887	biolink:NamedThing	2-polyprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinol O-methyltransferase activity	Catalysis of the reaction: 2-polyprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinol + S-adenosyl-L-methionine = ubiquinol-n + S-adenosyl-L-homocysteine + H+.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-10-28T22:17:54Z					molecular_function											owl:Class	
GO:0005773	biolink:NamedThing	vacuole	A closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material. Cells contain one or several vacuoles, that may have different functions from each other. Vacuoles have a diverse array of functions. They can act as a storage organelle for nutrients or waste products, as a degradative compartment, as a cost-effective way of increasing cell size, and as a homeostatic regulator controlling both turgor pressure and pH of the cytosol.	tmpzr1t_l9r_go_relaxed.owl	vacuolar carboxypeptidase Y				Wikipedia:Vacuole									cellular_component											owl:Class	
GO:0010920	biolink:NamedThing	negative regulation of inositol phosphate biosynthetic process	Any process that decreases the rate, frequency or extent of inositol phosphate biosynthesis. Inositol phosphate biosynthetic processes are the chemical reactions and pathways resulting in the formation of an inositol phosphate, 1,2,3,4,5,6-cyclohexanehexol, with one or more phosphate groups attached.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of inositol phosphate biosynthesis													biological_process											owl:Class	
GO:0006384	biolink:NamedThing	transcription initiation from RNA polymerase III promoter	Any process involved in the assembly of the RNA polymerase III preinitiation complex (PIC) at an RNA polymerase III promoter region of a DNA template, resulting in the subsequent synthesis of RNA from that promoter. The initiation phase includes PIC assembly and the formation of the first few bonds in the RNA chain, including abortive initiation, which occurs when the first few nucleotides are repeatedly synthesized and then released. Promoter clearance, or release, is the transition between the initiation and elongation phases of transcription.	tmpzr1t_l9r_go_relaxed.owl	transcription initiation from RNA polymerase III type 3 promoter|transcription initiation from RNA polymerase III type 2 promoter|transcription initiation from RNA polymerase III type 1 promoter|transcription initiation from RNA polymerase III hybrid type promoter|transcription initiation from Pol III promoter					Note that promoter clearance is represented as a separate step, not part_of either initiation or elongation.		krc	2010-08-19T04:33:52Z			GO:0001024|GO:0001022|GO:0001036|GO:0001023		biological_process											owl:Class	
GO:0098847	biolink:NamedThing	sequence-specific single stranded DNA binding	Binding to single-stranded DNA of a specific nucleotide composition.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0005753	biolink:NamedThing	mitochondrial proton-transporting ATP synthase complex	A proton-transporting ATP synthase complex found in the mitochondrial membrane.	tmpzr1t_l9r_go_relaxed.owl	mitochondrial respiratory chain complex V											GO:0016470		cellular_component											owl:Class	
GO:0050853	biolink:NamedThing	B cell receptor signaling pathway	A series of molecular signals initiated by the cross-linking of an antigen receptor on a B cell.	tmpzr1t_l9r_go_relaxed.owl	B-lymphocyte receptor signaling pathway|B-lymphocyte receptor signalling pathway|B cell receptor signalling pathway|B lymphocyte receptor signaling pathway|B-cell receptor signaling pathway|B-cell receptor signalling pathway|B lymphocyte receptor signalling pathway													biological_process											owl:Class	
GO:0050851	biolink:NamedThing	antigen receptor-mediated signaling pathway	A series of molecular signals initiated by the cross-linking of an antigen receptor on a B or T cell.	tmpzr1t_l9r_go_relaxed.owl	antigen receptor-mediated signalling pathway													biological_process											owl:Class	
GO:0044588	biolink:NamedThing	laminaribiose binding	Binding to laminaribiose, a disaccharide.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-04-26T01:19:40Z					molecular_function											owl:Class	
GO:0070492	biolink:NamedThing	oligosaccharide binding	Binding to an oligosaccharide, a molecule with between two and (about) 20 monosaccharide residues connected by glycosidic linkages.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0097225	biolink:NamedThing	sperm midpiece	The highly organized segment of the sperm flagellum which begins at the connecting piece and is characterized by the presence of 9 outer dense fibers (ODFs) that lie outside each of the 9 outer axonemal microtubule doublets and by a sheath of mitochondria that encloses the ODFs and the axoneme; the midpiece terminates about one-fourth of the way down the sperm flagellum at the annulus, which marks the beginning of the principal piece.	tmpzr1t_l9r_go_relaxed.owl								pr	2012-01-25T01:23:41Z					cellular_component											owl:Class	
GO:0106251	biolink:NamedThing	N4-acetylcytidine amidohydrolase activity	Catalysis of the reaction N4-acetylcytidine +H2O = cytidine + acetate.	tmpzr1t_l9r_go_relaxed.owl					RHEA:62932			hjd	2020-02-19T20:31:17Z					molecular_function											owl:Class	
GO:1901212	biolink:NamedThing	positive regulation of cardiac chamber formation	Any process that activates or increases the frequency, rate or extent of cardiac chamber formation.	tmpzr1t_l9r_go_relaxed.owl	upregulation of cardiac chamber formation|activation of cardiac chamber formation|up-regulation of heart chamber formation|upregulation of heart chamber formation|up regulation of cardiac chamber formation|up-regulation of cardiac chamber formation|up regulation of heart chamber formation|positive regulation of heart chamber formation|activation of heart chamber formation							rl	2012-07-31T07:19:05Z					biological_process											owl:Class	
GO:1901221	biolink:NamedThing	positive regulation of cardiac chamber morphogenesis	Any process that activates or increases the frequency, rate or extent of cardiac chamber morphogenesis.	tmpzr1t_l9r_go_relaxed.owl	upregulation of heart chamber morphogenesis|up regulation of cardiac chamber morphogenesis|up-regulation of cardiac chamber morphogenesis|activation of cardiac chamber morphogenesis|up regulation of heart chamber morphogenesis|positive regulation of heart chamber morphogenesis|activation of heart chamber morphogenesis|upregulation of cardiac chamber morphogenesis|up-regulation of heart chamber morphogenesis							rl	2012-08-06T17:59:42Z					biological_process											owl:Class	
GO:1990570	biolink:NamedThing	GDP-mannose transmembrane transport	The process in which GDP-mannose is transported across a membrane.	tmpzr1t_l9r_go_relaxed.owl	GDP-mannose transport							vw	2014-11-27T12:05:09Z			GO:0015784		biological_process											owl:Class	
GO:0090480	biolink:NamedThing	purine nucleotide-sugar transmembrane transport	The process in which a purine nucleotide-sugar is transported across a membrane. Purine nucleotide-sugars are purine nucleotides in glycosidic linkage with a monosaccharide or monosaccharide derivative.	tmpzr1t_l9r_go_relaxed.owl	purine nucleotide-sugar membrane transport|purine nucleotide-sugar transport					Note that this term is not intended for use in annotating lateral movement within membranes.		tb	2011-12-19T03:22:58Z			GO:0036079		biological_process											owl:Class	
GO:0030495	biolink:NamedThing	bacteriochlorophyll catabolic process	The chemical reactions and pathways resulting in the breakdown of bacteriochlorophyll, any of the chlorophylls of photosynthetic bacteria. They differ structurally from the chlorophylls of higher plants.	tmpzr1t_l9r_go_relaxed.owl	bacteriochlorophyll degradation|bacteriochlorophyll breakdown|bacteriochlorophyll catabolism													biological_process											owl:Class	
GO:0033020	biolink:NamedThing	cyclopentanol metabolic process	The chemical reactions and pathways involving cyclopentanol.	tmpzr1t_l9r_go_relaxed.owl	cyclopentanol metabolism													biological_process											owl:Class	
GO:1901720	biolink:NamedThing	negative regulation of NMS complex assembly	Any process that stops, prevents or reduces the frequency, rate or extent of NMS complex assembly. The NMS complex is involved in chromosome segregation.	tmpzr1t_l9r_go_relaxed.owl	downregulation of NMS complex association involved in chromosome segregation|down-regulation of NMS complex interaction involved in chromosome segregation|downregulation of KMN complex interaction involved in chromosome segregation|inhibition of KMN complex interaction involved in chromosome segregation|negative regulation of NMS complex association involved in chromosome segregation|inhibition of NMS complex association involved in chromosome segregation|down regulation of KMN complex assembly involved in chromosome segregation|inhibition of NMS complex interaction involved in chromosome segregation|down-regulation of NMS complex association involved in chromosome segregation|down-regulation of KMN complex interaction involved in chromosome segregation|down regulation of KMN network assembly involved in chromosome segregation|down regulation of NMS complex interaction involved in chromosome segregation|negative regulation of NMS complex assembly involved in kinetochore assembly|negative regulation of KMN network assembly involved in chromosome segregation|down regulation of NMS complex association involved in chromosome segregation|negative regulation of KMN complex interaction involved in chromosome segregation|down-regulation of KMN network assembly involved in chromosome segregation|downregulation of KMN network assembly involved in chromosome segregation|inhibition of KMN network assembly involved in chromosome segregation|downregulation of NMS complex interaction involved in chromosome segregation							jl	2012-12-20T11:44:22Z					biological_process											owl:Class	
GO:0035978	biolink:NamedThing	histone H2A-S139 phosphorylation	The modification of histone H2A by the addition of an phosphate group to a serine residue at position 139 of the histone.	tmpzr1t_l9r_go_relaxed.owl	histone H2A.x phosphorylation at S139					Residue 1 of histone H2AX is taken as the first residue following removal of the initiating Methionine (Met).		bf	2011-08-22T11:34:09Z					biological_process											owl:Class	
GO:0106156	biolink:NamedThing	peptidyl-lysine 4-dioxygenase activity	Catalysis of the reaction: protein L-lysine + 2-oxoglutarate + O2 = protein 4-hydroxy-L-lysine + succinate + CO2.	tmpzr1t_l9r_go_relaxed.owl					RHEA:57156			hjd	2018-11-26T14:59:18Z					molecular_function											owl:Class	
GO:0009845	biolink:NamedThing	seed germination	The physiological and developmental changes that occur in a seed commencing with water uptake (imbibition) and terminating with the elongation of the embryonic axis.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Germination#Seed_germination									biological_process											owl:Class	
GO:0014869	biolink:NamedThing	detection of muscle inactivity	The series of events in which a muscle inactivity stimulus is received by a cell and converted into a molecular signal.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0014870	biolink:NamedThing	response to muscle inactivity	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a muscle inactivity stimulus.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0048389	biolink:NamedThing	intermediate mesoderm development	The process whose specific outcome is the progression of the intermediate mesoderm over time, from its formation to the mature structure. The intermediate mesoderm is located between the lateral mesoderm and the paraxial mesoderm. It develops into the kidney and gonads.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0008313	biolink:NamedThing	gurken-activated receptor activity	Combining with the ligand Gurken to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	gurken receptor activity													molecular_function											owl:Class	
GO:0005006	biolink:NamedThing	epidermal growth factor-activated receptor activity	Combining with an epidermal growth factor and transmitting the signal across the plasma membrane to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	EGF receptor activity|TGF-alpha receptor activity|EGFR|epidermal growth factor receptor activity|transforming growth factor-alpha receptor activity					Note that this term represents an activity and not a gene product, and should only be used when the receptor binds the ligand EGF. For receptors that bind other growth factors, consider annotating to other terms under 'transmembrane signaling receptor activity ; GO:0004888.						GO:0005023		molecular_function											owl:Class	
GO:0038167	biolink:NamedThing	epidermal growth factor receptor signaling pathway via positive regulation of NF-kappaB transcription factor activity	The series of molecular signals generated as a consequence of an epidermal growth factor receptor binding to one of its physiological ligands, where the signal is passed on within the cell via activation of the transcription factor NF-kappaB.	tmpzr1t_l9r_go_relaxed.owl	epidermal growth factor receptor signalling pathway via positive regulation of NF-kappaB transcription factor activity|EGFR signaling pathway via activation of NF-kappaB							bf	2012-05-15T11:49:30Z					biological_process											owl:Class	
GO:0050526	biolink:NamedThing	poly(3-hydroxybutyrate) depolymerase activity	Catalysis of the reaction: H2O + poly[(R)-3-hydroxybutanoate](n) = poly[(R)-3-hydroxybutanoate](x) + poly[(R)-3-hydroxybutanoate](n-x); x is 1-5.	tmpzr1t_l9r_go_relaxed.owl	poly(HA(SCL)) depolymerase activity|poly(HASCL) depolymerase activity|poly(3HB) depolymerase activity|poly((R)-hydroxyalkanoic acid) depolymerase activity|poly[(R)-hydroxyalkanoic acid] depolymerase|poly(HA) depolymerase activity|poly[(R)-3-hydroxybutyrate] hydrolase activity|PHB depolymerase activity				MetaCyc:3.1.1.75-RXN|RHEA:11248|EC:3.1.1.75									molecular_function											owl:Class	
GO:0070610	biolink:NamedThing	regulation of fungal-type cell wall (1->3)-alpha-glucan biosynthetic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of (1->3)-alpha glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds, found in fungal-type cell walls, including those of ascospores.	tmpzr1t_l9r_go_relaxed.owl	regulation of fungal-type cell wall 1,3-alpha-glucan synthesis|regulation of fungal-type cell wall alpha-1,3-glucan formation|regulation of fungal-type cell wall 1,3-alpha-glucan formation|regulation of fungal-type cell wall 1,3-alpha-glucan biosynthesis|regulation of fungal-type cell wall alpha-1,3-glucan anabolism|regulation of fungal-type cell wall 1,3-alpha-glucan anabolism|regulation of fungal-type cell wall alpha-1,3-glucan synthesis|regulation of fungal-type cell wall alpha-1,3-glucan biosynthetic process|regulation of fungal type cell wall 1,3-alpha-glucan biosynthetic process|regulation of fungal-type cell wall alpha-1,3-glucan biosynthesis							mah	2009-04-29T01:32:19Z					biological_process											owl:Class	
GO:0102360	biolink:NamedThing	daphnetin 3-O-glucosyltransferase activity	Catalysis of the reaction: UDP-alpha-D-glucose(2-) + 7,8-dihydroxycoumarin <=> UDP(3-) + 3-O-beta-D-glucosyl-daphnetin + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-13452|EC:2.4.1.91									molecular_function											owl:Class	
GO:0098967	biolink:NamedThing	exocytic insertion of neurotransmitter receptor to postsynaptic membrane	The exocytic fusion of neurotransmitter receptor containing vesicles with the postsynaptic membrane resulting in the integration of NT receptors, enabling them to participate in neurotransmitter reception.  This process includes tethering and docking steps that prepare vesicles for fusion.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0070682	biolink:NamedThing	proteasome regulatory particle assembly	The aggregation, arrangement and bonding together of a mature, active proteasome regulatory particle complex.	tmpzr1t_l9r_go_relaxed.owl	proteasome regulatory complex assembly							mah	2009-06-02T03:46:29Z					biological_process											owl:Class	
GO:0060599	biolink:NamedThing	lateral sprouting involved in mammary gland duct morphogenesis	The process in which a branch forms along the side of a mammary duct.	tmpzr1t_l9r_go_relaxed.owl	mammary gland duct secondary branching							dph	2009-05-13T12:38:06Z					biological_process											owl:Class	
GO:0042103	biolink:NamedThing	positive regulation of T cell homeostatic proliferation	Any process that activates or increases the rate or extent of resting T cell proliferation.	tmpzr1t_l9r_go_relaxed.owl	stimulation of T cell homeostatic proliferation|positive regulation of T-lymphocyte homeostatic proliferation|positive regulation of T-cell homeostatic proliferation|up regulation of T cell homeostatic proliferation|positive regulation of T lymphocyte homeostatic proliferation|up-regulation of T cell homeostatic proliferation|positive regulation of resting T cell proliferation|activation of T cell homeostatic proliferation|upregulation of T cell homeostatic proliferation													biological_process											owl:Class	
GO:0046013	biolink:NamedThing	regulation of T cell homeostatic proliferation	Any process that modulates the frequency, rate or extent of resting T cell proliferation.	tmpzr1t_l9r_go_relaxed.owl	regulation of T-lymphocyte homeostatic proliferation|regulation of T-cell homeostatic proliferation|regulation of T lymphocyte homeostatic proliferation|regulation of resting T cell proliferation													biological_process											owl:Class	
GO:1901755	biolink:NamedThing	vitamin D3 biosynthetic process	The chemical reactions and pathways resulting in the formation of vitamin D3.	tmpzr1t_l9r_go_relaxed.owl	calciol anabolism|calciol formation|calciol biosynthetic process|cholecalciferol biosynthetic process|vitamin D3 anabolism|calciol synthesis|vitamin D3 biosynthesis|calciol biosynthesis|cholecalciferol biosynthesis|vitamin D3 synthesis|vitamin D3 formation							yaf	2013-01-14T11:11:09Z					biological_process											owl:Class	
GO:0042368	biolink:NamedThing	vitamin D biosynthetic process	The chemical reactions and pathways resulting in the formation of vitamin D, any of a group of related, fat-soluble compounds that are derived from delta-5,7 steroids and play a central role in calcium metabolism. Specific forms of vitamin D include calciferol (ergocalciferol; vitamin D2) and cholecalciferol (calciol; vitamin D3).	tmpzr1t_l9r_go_relaxed.owl	vitamin D synthesis|ergocalciferol biosynthesis|cholecalciferol biosynthesis|cholecalciferol biosynthetic process|ergocalciferol biosynthetic process|vitamin D formation|calciferol biosynthetic process|calciferol biosynthesis|vitamin D biosynthesis|vitamin D anabolism													biological_process											owl:Class	
GO:0031394	biolink:NamedThing	positive regulation of prostaglandin biosynthetic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of prostaglandin.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of prostaglandin anabolism|positive regulation of prostaglandin formation|up regulation of prostaglandin biosynthetic process|activation of prostaglandin biosynthetic process|positive regulation of prostaglandin biosynthesis|up-regulation of prostaglandin biosynthetic process|upregulation of prostaglandin biosynthetic process|positive regulation of prostaglandin synthesis|stimulation of prostaglandin biosynthetic process													biological_process											owl:Class	
GO:0047375	biolink:NamedThing	N-acetylgalactosaminoglycan deacetylase activity	Catalysis of the reaction: H2O + N-acetyl-D-galactosaminoglycan = acetate + D-galactosaminoglycan.	tmpzr1t_l9r_go_relaxed.owl	N-acetyl galactosaminoglycan deacetylase activity|Vi-polysaccharide deacetylase activity|N-acetyl-D-galactosaminoglycan acetylhydrolase activity|polysaccharide deacetylase activity				EC:3.1.1.58|MetaCyc:3.1.1.58-RXN									molecular_function											owl:Class	
GO:0005612	biolink:NamedThing	laminin-7 complex	A laminin complex composed of alpha3, beta2 and gamma1 polypeptide chains.	tmpzr1t_l9r_go_relaxed.owl	laminin-321 complex|laminin-7A													cellular_component											owl:Class	
GO:0018423	biolink:NamedThing	protein C-terminal leucine carboxyl O-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + protein L-leucine = S-adenosyl-L-homocysteine + protein L-leucine methyl ester. This modification occurs only at the oxygen atoms of the free alpha carboxyl group of a leucine residue at the C-terminus of the protein.	tmpzr1t_l9r_go_relaxed.owl	protein phosphatase methyltransferase activity|protein-leucine O-methyltransferase activity				Reactome:R-HSA-8856945									molecular_function											owl:Class	
GO:0003880	biolink:NamedThing	protein C-terminal carboxyl O-methyltransferase activity	Catalysis of the transfer of a methyl group to the oxygen atom of a carboxyl group at the C-terminal of a protein.	tmpzr1t_l9r_go_relaxed.owl	C-terminal protein carboxyl methyltransferase activity													molecular_function											owl:Class	
GO:0062162	biolink:NamedThing	positive regulation of pyocyanine biosynthetic process	Any process that increases the frequency, rate or extent of a pyocyanine biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of pyocyanin biosynthetic process							dph	2019-11-06T14:40:35Z					biological_process											owl:Class	
GO:0071764	biolink:NamedThing	nuclear outer membrane organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear outer membrane.	tmpzr1t_l9r_go_relaxed.owl	nuclear outer membrane organisation|nuclear outer membrane organization and biogenesis							mah	2010-03-29T04:03:37Z					biological_process											owl:Class	
GO:0075217	biolink:NamedThing	negative regulation of spore encystment on host	Any process that stops, prevents, or reduces the frequency, rate or extent of spore encystment on host. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0008835	biolink:NamedThing	diaminohydroxyphosphoribosylaminopyrimidine deaminase activity	Catalysis of the reaction: 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)-pyrimidine + H(2)O + H(+) = 5-amino-6-(5-phosphoribosylamino)uracil + NH(4)(+).	tmpzr1t_l9r_go_relaxed.owl	2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)-pyrimidine 2-aminohydrolase activity|2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine 2-aminohydrolase activity|2,5-diamino-6-(ribosylamino)-4(3H)-pyrimidinone 5'-phosphate deaminase activity				EC:3.5.4.26|RHEA:21868|MetaCyc:RIBOFLAVINSYNDEAM-RXN|KEGG_REACTION:R03459							GO:0008485		molecular_function											owl:Class	
GO:0120053	biolink:NamedThing	ribitol beta-1,4-xylosyltransferase activity	Catalysis of the reaction: UDP-D-xylose + D-ribitol 5-phosphate-R = UDP + beta1,4-xylosyl-D-ribitol 5-phosphate-R.	tmpzr1t_l9r_go_relaxed.owl								krc	2017-06-13T19:35:01Z					molecular_function											owl:Class	
GO:1901628	biolink:NamedThing	positive regulation of postsynaptic membrane organization	Any process that activates or increases the frequency, rate or extent of postsynaptic membrane organization.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of postsynaptic membrane organisation|up-regulation of postsynaptic membrane organization|activation of postsynaptic membrane organisation|up regulation of postsynaptic membrane organization|activation of postsynaptic membrane organization|positive regulation of post-synaptic membrane organization|up regulation of postsynaptic membrane organisation|up-regulation of postsynaptic membrane organisation|upregulation of postsynaptic membrane organization|upregulation of postsynaptic membrane organisation							ans	2012-11-15T11:40:24Z					biological_process											owl:Class	
GO:0050559	biolink:NamedThing	copalyl diphosphate synthase activity	Catalysis of the reaction: all-trans-geranylgeranyl diphosphate = (+)-copalyl diphosphate.	tmpzr1t_l9r_go_relaxed.owl	diterpene cyclase activity|(+)-copalyl-diphosphate lyase (decyclizing)				EC:5.5.1.12|KEGG_REACTION:R06298|RHEA:24316|MetaCyc:RXN-4861									molecular_function											owl:Class	
GO:2001204	biolink:NamedThing	regulation of osteoclast development	Any process that modulates the frequency, rate or extent of osteoclast development.	tmpzr1t_l9r_go_relaxed.owl	regulation of osteoclast cell development							yaf	2011-11-10T10:58:59Z					biological_process											owl:Class	
GO:0055093	biolink:NamedThing	response to hyperoxia	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating increased oxygen tension.	tmpzr1t_l9r_go_relaxed.owl	response to increased oxygen tension|response to hyperoxic stress													biological_process											owl:Class	
GO:0036296	biolink:NamedThing	response to increased oxygen levels	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting an increase in the level of oxygen.	tmpzr1t_l9r_go_relaxed.owl	response to raised oxygen levels					This term should be used when an increase in oxygen levels is not considered a stress response. For a hyperoxic stress response, consider instead 'response to hyperoxia ; GO:0055093.		bf	2012-07-20T01:10:48Z					biological_process											owl:Class	
GO:1902548	biolink:NamedThing	negative regulation of cellular response to vascular endothelial growth factor stimulus	Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to vascular endothelial growth factor stimulus.	tmpzr1t_l9r_go_relaxed.owl	down regulation of cellular response to vascular endothelial growth factor stimulus|down-regulation of cellular response to VEGFB|negative regulation of cellular response to VEGFA|down-regulation of cellular response to VEGF|down regulation of cellular response to VEGFA|inhibition of cellular response to vascular endothelial growth factor|negative regulation of cellular response to vascular endothelial growth factor|negative regulation of cellular response to VEGFB|down-regulation of cellular response to vascular endothelial growth factor stimulus|inhibition of cellular response to VEGF|negative regulation of cellular response to VEGF|downregulation of cellular response to VEGF|inhibition of cellular response to VEGFA|inhibition of cellular response to VEGFB|downregulation of cellular response to vascular endothelial growth factor stimulus|downregulation of cellular response to VEGFA|downregulation of cellular response to vascular endothelial growth factor|down regulation of cellular response to vascular endothelial growth factor|down-regulation of cellular response to vascular endothelial growth factor|inhibition of cellular response to vascular endothelial growth factor stimulus|downregulation of cellular response to VEGFB|down regulation of cellular response to VEGF|down-regulation of cellular response to VEGFA|down regulation of cellular response to VEGFB					ADAMTS12 (UniProt ID P58397) in human in PMID:17895370 inhibits the formation of VEGF-induced tubular structures in BAE-1 cells (endothelial cell line).		rl	2013-12-04T15:15:03Z					biological_process											owl:Class	
GO:2000143	biolink:NamedThing	negative regulation of DNA-templated transcription, initiation	Any process that stops, prevents, or reduces the frequency, rate or extent of DNA-templated transcription initiation.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of transcription initiation, DNA-dependent|negative regulation of DNA-dependent transcription, initiation|negative regulation of initiation of DNA-dependent transcription							mah	2010-10-01T09:11:40Z					biological_process											owl:Class	
GO:0061349	biolink:NamedThing	planar cell polarity pathway involved in cardiac right atrium morphogenesis	The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors including C-Jun N-terminal kinase (JNK) to modulate cytoskeletal elements and control cell polarity that contributes to the shaping of the cardiac right atrium.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-10-01T10:52:01Z					biological_process											owl:Class	
GO:1905212	biolink:NamedThing	positive regulation of fibroblast chemotaxis	Any process that activates or increases the frequency, rate or extent of fibroblast chemotaxis.	tmpzr1t_l9r_go_relaxed.owl	up regulation of fibroblast chemotaxis|upregulation of fibroblast chemotaxis|up-regulation of fibroblast chemotaxis|activation of fibroblast chemotaxis							sl	2016-06-02T20:08:59Z					biological_process											owl:Class	
GO:0010836	biolink:NamedThing	negative regulation of protein ADP-ribosylation	Any process that decreases the frequency, rate or extent of protein ADP-ribosylation. Protein ADP-ribosylation is the transfer, from NAD, of ADP-ribose to protein amino acids.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of protein amino acid ADP-ribosylation													biological_process											owl:Class	
GO:0090406	biolink:NamedThing	pollen tube	A tubular cell projection that is part of a pollen tube cell and extends from a pollen grain.	tmpzr1t_l9r_go_relaxed.owl						Carries the male gametes to into or near the ovule. May be branched in gymnosperms. This term replaces the obsolete term PO:0006345. Part of pollen tube cell (PO:0025195).		tb	2011-01-10T01:59:40Z					cellular_component											owl:Class	
GO:0004854	biolink:NamedThing	xanthine dehydrogenase activity	Catalysis of the reaction: xanthine + NAD+ + H2O = urate + NADH + H+.	tmpzr1t_l9r_go_relaxed.owl	xanthine:NAD+ oxidoreductase activity|NAD-xanthine dehydrogenase activity|xanthine oxidoreductase activity|xanthine-NAD oxidoreductase activity|xanthine/NAD(+) oxidoreductase activity|xanthine/NAD+ oxidoreductase activity				MetaCyc:RXN0-901|RHEA:16669|EC:1.17.1.4									molecular_function											owl:Class	
GO:0033137	biolink:NamedThing	negative regulation of peptidyl-serine phosphorylation	Any process that stops, prevents, or reduces the frequency, rate or extent of the phosphorylation of peptidyl-serine.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0030785	biolink:NamedThing	[ribulose-bisphosphate carboxylase]-lysine N-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + [ribulose-1,5-bisphosphate carboxylase]-lysine = S-adenosyl-L-homocysteine + [ribulose-1,5-bisphosphate carboxylase]-N6-methyl-L-lysine.	tmpzr1t_l9r_go_relaxed.owl	RuBisCO methyltransferase activity|ribulose-bisphosphate carboxylase-lysine N-methyltransferase activity|RuBisCO LSMT activity|S-adenosyl-L-methionine:3-phospho-D-glycerate-carboxy-lyase (dimerizing)-lysine N6-methyltransferase activity|S-adenosyl-L-methionine:3-phospho-D-glycerate-carboxy-lyase (dimerizing)-lysine 6-N-methyltransferase activity|ribulose-1,5-bisphosphate carboxylase/oxygenase large subunit epsilonN-methyltransferase activity|ribulose-bisphosphate-carboxylase/oxygenase N-methyltransferase activity				MetaCyc:2.1.1.127-RXN|RHEA:50996|EC:2.1.1.127									molecular_function											owl:Class	
GO:0004142	biolink:NamedThing	diacylglycerol cholinephosphotransferase activity	Catalysis of the reaction: CDP-choline + 1,2-diacylglycerol = CMP + a phosphatidylcholine.	tmpzr1t_l9r_go_relaxed.owl	cytidine diphosphocholine glyceride transferase activity|cytidine diphosphorylcholine diglyceride transferase activity|CDP-choline:1,2-diacylglycerol cholinephosphotransferase activity|1-alkyl-2-acetylglycerol cholinephosphotransferase activity|CDP-choline diglyceride phosphotransferase activity|1-alkyl-2-acetyl-sn-glycerol cholinephosphotransferase activity|cholinephosphotransferase activity|sn-1,2-diacylglycerol cholinephosphotransferase activity|1-alkyl-2-acetyl-m-glycerol:CDPcholine choline phosphotransferase activity|alkylacylglycerol choline phosphotransferase activity|CPT|alkylacylglycerol cholinephosphotransferase activity|diacylglycerol choline phosphotransferase activity|phosphorylcholine--glyceride transferase activity|phosphocholine diacylglyceroltransferase activity				Reactome:R-HSA-1482961|RHEA:32939|MetaCyc:RXN-5781|Reactome:R-HSA-1482973|EC:2.7.8.2									molecular_function											owl:Class	
GO:0017169	biolink:NamedThing	CDP-alcohol phosphatidyltransferase activity	Catalysis of the reaction: CDP + alcohol = CMP + phosphatidyl alcohol.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0046166	biolink:NamedThing	glyceraldehyde-3-phosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of glyceraldehyde-3-phosphate, an important intermediate in glycolysis.	tmpzr1t_l9r_go_relaxed.owl	glyceraldehyde-3-phosphate biosynthesis|glyceraldehyde 3-phosphate biosynthesis|glyceraldehyde-3-phosphate synthesis|glyceraldehyde-3-phosphate anabolism|glyceraldehyde-3-phosphate formation|glyceraldehyde 3-phosphate biosynthetic process													biological_process											owl:Class	
GO:0008628	biolink:NamedThing	hormone-mediated apoptotic signaling pathway	A series of molecular signals mediated by the detection of a hormone, and which triggers the apoptotic signaling pathway in a cell. The pathway starts with reception of a hormone signal, and ends when the execution phase of apoptosis is triggered.	tmpzr1t_l9r_go_relaxed.owl	induction of apoptosis by hormones|apoptotic signaling pathway in response to hormone	http://wiki.geneontology.org/index.php/Apoptosis_Curation_Manual#Other_children_of_apoptotic_signaling_pathway				This term is placed under GO:0097190 apoptotic signaling pathway, rather than under one of its more specific children terms, to cover for the variety of apoptosis signaling mechanisms that different hormones may use.								biological_process											owl:Class	
GO:0106054	biolink:NamedThing	tRNA U34 thiol-transferase activity	Catalysis of the reaction: uridine34 in tRNA + a [TusE sulfur carrier protein]-S-sulfanylcysteine + ATP + a reduced electron acceptor = a 2-thiouridine34 in tRNA + a [TusE sulfur carrier protein]-L-cysteine + AMP + an oxidized electron acceptor + diphosphate + H+.	tmpzr1t_l9r_go_relaxed.owl	tRNA U34 2-thiouridylase|tRNA-specific 2-thiouridylase							hjd	2017-09-05T19:10:12Z					molecular_function											owl:Class	
GO:0009662	biolink:NamedThing	etioplast organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an etioplast. An etioplast is a plastid arrested in the development of chloroplasts from proplastids due to absence of light or low light conditions.	tmpzr1t_l9r_go_relaxed.owl	etioplast organization and biogenesis|etioplast organisation													biological_process											owl:Class	
GO:0016508	biolink:NamedThing	long-chain-enoyl-CoA hydratase activity	Catalysis of the reaction: a long-chain (3S)-3-hydroxyacyl-CoA = a long-chain trans-2-enoyl-CoA + H2O. A long-chain acyl-CoA is an acyl-CoA thioester where the acyl chain contains 13 to 22 carbon atoms.	tmpzr1t_l9r_go_relaxed.owl	long-chain enoyl coenzyme A hydratase activity|long-chain-(3S)-3-hydroxyacyl-CoA hydro-lyase activity				Reactome:R-HSA-2066780|Reactome:R-HSA-2066778|Reactome:R-HSA-389986|EC:4.2.1.74|Reactome:R-HSA-390252|MetaCyc:LONG-CHAIN-ENOYL-COA-HYDRATASE-RXN|Reactome:R-HSA-6809263									molecular_function											owl:Class	
GO:0031597	biolink:NamedThing	cytosolic proteasome complex	A proteasome complex found in the cytosol of a cell.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0034810	biolink:NamedThing	4,5-dihydroxybenzo(a)pyrene dioxygenase activity	Catalysis of the reaction: 4,5-dihydroxybenzo(a)pyrene + O2 = 4,5-chrysenedicarboxylate.	tmpzr1t_l9r_go_relaxed.owl					EC:1.13.11.-|UM-BBD_reactionID:r1128									molecular_function											owl:Class	
GO:0033200	biolink:NamedThing	inositol heptakisphosphate 5-kinase activity	Catalysis of the reaction: ATP + 4-diphospho-1D-myo-inositol (1,2,3,5,6)pentakisphosphate = 4,5-bisdiphosphoinositol-1D-myoinositol (1,2,3,6)tetrakisphosphate, and ATP + 6-diphospho-1D-myo-inositol (1,2,3,4,5)pentakisphosphate = 5,6-bisdiphosphoinositol-1D-myoinositol (1,2,3,4)tetrakisphosphate.	tmpzr1t_l9r_go_relaxed.owl	diphosphoinositol-pentakisphosphate 5-kinase activity|IP7 5-kinase activity													molecular_function											owl:Class	
GO:0050449	biolink:NamedThing	casbene synthase activity	Catalysis of the reaction: all-trans-geranylgeranyl diphosphate = casbene + diphosphate.	tmpzr1t_l9r_go_relaxed.owl	geranylgeranyl-diphosphate diphosphate-lyase (cyclizing, casbene-forming)|geranylgeranyl-diphosphate diphosphate-lyase (cyclizing)|casbene synthetase activity				MetaCyc:CASBENE-SYNTHASE-RXN|KEGG_REACTION:R02064|EC:4.2.3.8|RHEA:14901									molecular_function											owl:Class	
GO:0042496	biolink:NamedThing	detection of diacyl bacterial lipopeptide	The series of events in which a diacylated bacterial lipopeptide stimulus is received by a cell and converted into a molecular signal. Diacylated bacterial lipoproteins are lipopeptides of bacterial origin containing a nonprotein moiety consisting of two acyl groups.	tmpzr1t_l9r_go_relaxed.owl	perception of diacylated bacterial lipopeptide|perception of diacylated bacterial lipoprotein|detection of diacylated bacterial lipoprotein					Note that bacterial lipopeptides are derived from bacterial lipoproteins, but the two terms are sometimes used interchangeably in the literature.								biological_process											owl:Class	
GO:0071724	biolink:NamedThing	response to diacyl bacterial lipopeptide	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diacylated bacterial lipopeptide stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to diacylated bacterial lipoprotein					Note that bacterial lipopeptides are derived from bacterial lipoproteins, but the two terms are sometimes used interchangeably in the literature.		mah	2010-03-17T02:14:41Z					biological_process											owl:Class	
GO:0031474	biolink:NamedThing	myosin IV complex	A myosin complex containing one or more class IV myosin heavy chains and associated light chains; myosin IV is relatively uncharacterized, but is predicted to have a single motor domain, one IQ motif and a tail with a Myosin Tail Homology (myTH4) domain homologous to that in the tails of myosins VII and XV.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:1904115	biolink:NamedThing	axon cytoplasm	Any cytoplasm that is part of a axon.	tmpzr1t_l9r_go_relaxed.owl	axoplasm							sl	2015-04-06T18:13:14Z					cellular_component											owl:Class	
GO:0032767	biolink:NamedThing	copper-dependent protein binding	Binding to a protein or protein complex, in the presence of copper.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0061730	biolink:NamedThing	C-rich strand telomeric DNA binding	Binding to C-rich, single-stranded, telomere-associated DNA.	tmpzr1t_l9r_go_relaxed.owl								dph	2015-08-20T09:08:27Z					molecular_function											owl:Class	
GO:1905098	biolink:NamedThing	negative regulation of guanyl-nucleotide exchange factor activity	Any process that stops, prevents or reduces the frequency, rate or extent of guanyl-nucleotide exchange factor activity.	tmpzr1t_l9r_go_relaxed.owl	inhibition of GEF|down-regulation of guanyl-nucleotide releasing factor|inhibition of guanyl-nucleotide release factor activity|down regulation of guanyl-nucleotide release factor activity|down regulation of guanyl-nucleotide exchange factor activity|downregulation of GEF|down-regulation of GNRP|inhibition of guanyl-nucleotide releasing factor|inhibition of GNRP|down-regulation of guanyl-nucleotide release factor activity|down-regulation of guanyl-nucleotide exchange factor activity|negative regulation of GEF|inhibition of guanyl-nucleotide exchange factor activity|downregulation of guanyl-nucleotide exchange factor activity|inhibition of GDP-dissociation stimulator activity|negative regulation of GDP-dissociation stimulator activity|negative regulation of GNRP|down-regulation of GDS|negative regulation of GDS|down-regulation of GDP-dissociation stimulator activity|down-regulation of GEF|downregulation of GDS|downregulation of guanyl-nucleotide release factor activity|down regulation of guanyl-nucleotide releasing factor|downregulation of guanyl-nucleotide releasing factor|down regulation of GEF|down regulation of GNRP|negative regulation of guanyl-nucleotide releasing factor|inhibition of GDS|downregulation of GDP-dissociation stimulator activity|down regulation of GDP-dissociation stimulator activity|down regulation of GDS|downregulation of GNRP|negative regulation of guanyl-nucleotide release factor activity	https://github.com/geneontology/go-ontology/issues/18750						sl	2016-03-31T16:09:45Z					biological_process											owl:Class	
GO:0042911	biolink:NamedThing	acridine transmembrane transporter activity	Enables the directed movement of acridine (10-azaanthracene), a heterocyclic ring compound found in crude coal-tar anthracene from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	acridine transporter activity													molecular_function											owl:Class	
GO:1903208	biolink:NamedThing	negative regulation of hydrogen peroxide-induced neuron death	Any process that stops, prevents or reduces the frequency, rate or extent of hydrogen peroxide-induced neuron death.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of neuron death in response to H2O2|negative regulation of neuronal cell death in response to hydrogen peroxide|inhibition of neuron death in response to hydrogen peroxide|inhibition of hydrogen peroxide-induced neuron death|down-regulation of neuronal cell death in response to hydrogen peroxide|down regulation of hydrogen peroxide-induced neuron death|down regulation of neuron death in response to hydrogen peroxide|down-regulation of neuron death in response to hydrogen peroxide|down-regulation of hydrogen peroxide-induced neuron death|down-regulation of neuron death in response to H2O2|downregulation of neuron death in response to hydrogen peroxide|neuroprotection against hydrogen peroxide|protection against hydrogen peroxide-induced neuron death|down regulation of neuronal cell death in response to hydrogen peroxide|downregulation of hydrogen peroxide-induced neuron death|downregulation of neuronal cell death in response to hydrogen peroxide|neuroprotection against H2O2-induced cell death|downregulation of neuron death in response to H2O2|protection against H2O2-induced neuron death|inhibition of neuronal cell death in response to hydrogen peroxide|inhibition of neuron death in response to H2O2|negative regulation of neuron death in response to hydrogen peroxide|down regulation of neuron death in response to H2O2							bf	2014-07-21T16:27:11Z					biological_process											owl:Class	
GO:0046409	biolink:NamedThing	p-coumarate 3-hydroxylase activity	Catalysis of the reaction: shikimate or quinate ester of p-coumaric acid + NADPH + H+ + O2 = caffeic acid conjugate (caffeoyl shikimic acid or chlorogenic acid) + H2O + NADP+.	tmpzr1t_l9r_go_relaxed.owl	cytochrome P450 CYP98A3													molecular_function											owl:Class	
GO:0003356	biolink:NamedThing	regulation of cilium beat frequency	Any process that modulates the frequency of cilium movement, the directed, self-propelled movement of a cilium.	tmpzr1t_l9r_go_relaxed.owl	regulation of microtubule-based flagellum beat frequency|regulation of flagellum beat frequency					Note that we deem cilium and microtubule-based flagellum to be equivalent.		dph	2009-12-03T10:27:12Z			GO:0036144		biological_process											owl:Class	
GO:0090652	biolink:NamedThing	basolateral cytoplasm	The region of the cytoplasm located at the basolateral side of the cell. Used in reference to animal polarized epithelial cells.	tmpzr1t_l9r_go_relaxed.owl								tb	2015-07-01T15:46:19Z					cellular_component											owl:Class	
GO:0045766	biolink:NamedThing	positive regulation of angiogenesis	Any process that activates or increases angiogenesis.	tmpzr1t_l9r_go_relaxed.owl	activation of angiogenesis|upregulation of angiogenesis|stimulation of angiogenesis|up regulation of angiogenesis|up-regulation of angiogenesis													biological_process											owl:Class	
GO:0045898	biolink:NamedThing	regulation of RNA polymerase II transcription preinitiation complex assembly	Any process that modulates the frequency, rate or extent of RNA polymerase II transcriptional preinitiation complex assembly.	tmpzr1t_l9r_go_relaxed.owl	regulation of RNA polymerase II transcriptional preinitiation complex formation|regulation of RNA polymerase II transcriptional preinitiation complex assembly|regulation of RNA polymerase II transcriptional pre-initiation complex biosynthesis|regulation of RNA polymerase II transcriptional pre-initiation complex assembly													biological_process											owl:Class	
GO:1900637	biolink:NamedThing	regulation of asperfuranone biosynthetic process	Any process that modulates the frequency, rate or extent of asperfuranone biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of asperfuranone formation|regulation of asperfuranone biosynthesis|regulation of asperfuranone synthesis|regulation of asperfuranone anabolism							di	2012-05-22T03:49:55Z					biological_process											owl:Class	
GO:1905911	biolink:NamedThing	positive regulation of dauer entry	Any process that activates or increases the frequency, rate or extent of dauer entry.	tmpzr1t_l9r_go_relaxed.owl	upregulation of dauer entry|up-regulation of nematode entry into dormancy|up regulation of nematode entry into dormancy|activation of nematode entry into dormancy|upregulation of nematode entry into dormancy|positive regulation of nematode entry into dormancy|up regulation of dauer entry|up-regulation of dauer entry|activation of dauer entry							hbye	2017-02-06T15:34:20Z					biological_process											owl:Class	
GO:0099117	biolink:NamedThing	protein transport along microtubule to cell tip	The movement of a protein along a microtubule to the cell-tip, mediated by motor proteins.	tmpzr1t_l9r_go_relaxed.owl								vw	2015-09-15T11:09:54Z					biological_process											owl:Class	
GO:0017057	biolink:NamedThing	6-phosphogluconolactonase activity	Catalysis of the reaction: 6-O-phosphono-D-glucono-1,5-lactone + H(2)O = 6-phospho-D-gluconate + H(+).	tmpzr1t_l9r_go_relaxed.owl	6-phospho-D-glucono-1,5-lactone lactonohydrolase activity|6-PGL|phosphogluconolactonase activity				MetaCyc:6PGLUCONOLACT-RXN|KEGG_REACTION:R02035|RHEA:12556|EC:3.1.1.31|Reactome:R-HSA-71296									molecular_function											owl:Class	
GO:0019413	biolink:NamedThing	acetate biosynthetic process	The chemical reactions and pathways resulting in the formation of acetate, the anion of acetic acid.	tmpzr1t_l9r_go_relaxed.owl	acetate biosynthesis|acetate anabolism|acetate formation|acetate synthesis													biological_process											owl:Class	
GO:0051135	biolink:NamedThing	positive regulation of NK T cell activation	Any process that activates or increases the frequency, rate or extent of natural killer T cell activation.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of NKT cell activation|activation of NK T cell activation|positive regulation of NK T-cell activation|up regulation of NK T cell activation|positive regulation of NT cell activation|upregulation of NK T cell activation|stimulation of NK T cell activation|positive regulation of NK T-lymphocyte activation|positive regulation of NK T lymphocyte activation|up-regulation of NK T cell activation|positive regulation of natural T cell activation|positive regulation of natural killer T cell activation													biological_process											owl:Class	
GO:0071519	biolink:NamedThing	actomyosin contractile ring actin filament bundle assembly	A process of actin filament bundle formation that occurs in the context of assembling an actomyosin contractile ring during cytokinesis.	tmpzr1t_l9r_go_relaxed.owl	actin filament bundle assembly involved in cytokinetic actomyosin contractile ring assembly|actin filament bundle assembly involved in actomyosin contractile ring formation							mah	2010-01-06T05:27:59Z					biological_process											owl:Class	
GO:0022027	biolink:NamedThing	interkinetic nuclear migration	The movement of the nucleus of the ventricular zone cell between the apical and the basal zone surfaces. Mitosis occurs when the nucleus is near the apical surface, that is, the lumen of the ventricle.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0004971	biolink:NamedThing	AMPA glutamate receptor activity	An ionotropic glutamate receptor activity that exhibits fast gating by glutamate and acts by opening a cation channel permeable to sodium, potassium, and, in the absence of a GluR2 subunit, calcium.	tmpzr1t_l9r_go_relaxed.owl	alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity|AMPA receptor activity					Note that this term represents an activity and not a gene product. Consider also annotating to the molecular function terms 'ionotropic glutamate receptor activity ; GO:0004970' and 'cation channel activity ; GO:0005261'.								molecular_function											owl:Class	
GO:1900640	biolink:NamedThing	regulation of austinol biosynthetic process	Any process that modulates the frequency, rate or extent of austinol biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of austinol biosynthesis|regulation of austinol synthesis|regulation of austinol anabolism|regulation of austinol formation							di	2012-05-22T03:57:33Z					biological_process											owl:Class	
GO:0018546	biolink:NamedThing	nitrobenzene nitroreductase activity	Catalysis of the reaction: nitrobenzene + 2 NADPH + 2 H+ = hydroxyaminobenzene + 2 NADP+ + H2O.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_enzymeID:e0245|RHEA:52884|MetaCyc:RXN-8815									molecular_function											owl:Class	
GO:0052618	biolink:NamedThing	coenzyme F420-0:L-glutamate ligase activity	Catalysis of the reaction: GTP + L-glutamate + factor F420-0 = GDP + H+ + factor gamma-F420-1 + phosphate.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-8080|RHEA:30555|EC:6.3.2.31									molecular_function											owl:Class	
GO:0043773	biolink:NamedThing	coenzyme F420-0 gamma-glutamyl ligase activity	Catalysis of the reactions: (1) GTP + F420-0 + L-glutamate = GDP + phosphate + F420-1, and (2) GTP + F420-1 + L-glutamate = GDP + phosphate + gamma-F420-2. This is the GTP-dependent successive addition of two L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form F420-0-glutamyl-glutamate (F420-2), with a gamma-linkage between the two glutamates.	tmpzr1t_l9r_go_relaxed.owl	F420-0 gamma-glutamyl ligase activity													molecular_function											owl:Class	
GO:0030557	biolink:NamedThing	tRNA modification guide activity	Specifies the site of a posttranscriptional modification in a tRNA molecule by base pairing with a short sequence around the target residue.	tmpzr1t_l9r_go_relaxed.owl						Note that this term describes the activity of a nucleic acid, usually RNA, gene product that interacts with other RNA molecules via base pairing; it should not be used to annotate proteins.								molecular_function											owl:Class	
GO:1901839	biolink:NamedThing	regulation of RNA polymerase I regulatory region sequence-specific DNA binding	Any process that modulates the frequency, rate or extent of RNA polymerase I regulatory region sequence-specific DNA binding.	tmpzr1t_l9r_go_relaxed.owl								sart	2013-01-23T10:24:33Z					biological_process											owl:Class	
GO:0033009	biolink:NamedThing	nucleomorph	A small, vestigial nucleus found in some plastids that derive from a eukaryotic endosymbiont. Observed in chlorarachniophytes and cryptomonads, which acquired their plastids from a green and red alga respectively.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Nucleomorph									cellular_component											owl:Class	
GO:1901462	biolink:NamedThing	positive regulation of response to formic acid	Any process that activates or increases the frequency, rate or extent of response to formic acid.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of response to formic acid|activation of response to formic acid|upregulation of response to formic acid|up regulation of response to formic acid							tt	2012-10-02T14:29:20Z					biological_process											owl:Class	
GO:0045839	biolink:NamedThing	negative regulation of mitotic nuclear division	Any process that stops, prevents or reduces the rate or extent of mitosis. Mitosis is the division of the eukaryotic cell nucleus to produce two daughter nuclei that, usually, contain the identical chromosome complement to their mother.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of mitosis|down-regulation of mitosis|downregulation of mitosis|down regulation of mitosis|inhibition of mitosis													biological_process											owl:Class	
GO:0042255	biolink:NamedThing	ribosome assembly	The aggregation, arrangement and bonding together of the mature ribosome and of its subunits.	tmpzr1t_l9r_go_relaxed.owl	ribosomal subunit assembly											GO:0042257		biological_process											owl:Class	
GO:0034850	biolink:NamedThing	isooctane monooxygenase activity	Catalysis of the reaction: isooctane + 1/2 O2 = 2,4,4-trimethyl-1-pentanol.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r1269|EC:1.13.12.-									molecular_function											owl:Class	
GO:1902566	biolink:NamedThing	regulation of eosinophil activation	Any process that modulates the frequency, rate or extent of eosinophil activation.	tmpzr1t_l9r_go_relaxed.owl								ecu	2013-12-10T15:54:35Z					biological_process											owl:Class	
GO:0009057	biolink:NamedThing	macromolecule catabolic process	The chemical reactions and pathways resulting in the breakdown of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.	tmpzr1t_l9r_go_relaxed.owl	multicellular organismal macromolecule catabolic process|macromolecule degradation|macromolecule catabolism|biopolymer catabolic process|macromolecule breakdown											GO:0044266|GO:0043285		biological_process											owl:Class	
GO:0032596	biolink:NamedThing	protein transport into membrane raft	The directed movement of a protein into a membrane raft. Membrane rafts are small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes.	tmpzr1t_l9r_go_relaxed.owl	receptor translocation into membrane raft|receptor transport into membrane raft|protein translocation into membrane raft|protein transport into lipid raft													biological_process											owl:Class	
GO:1990719	biolink:NamedThing	C1 axonemal microtubule	One of two microtubules present in the axonemal central pair. It is distinguishable from the C2 axonemal microtubule (also called C2 tubule) by the presence of differing protein components of the projections.	tmpzr1t_l9r_go_relaxed.owl	C1 tubule							krc	2015-03-27T22:55:12Z					cellular_component											owl:Class	
GO:0007555	biolink:NamedThing	regulation of ecdysteroid secretion	Any process that modulates the frequency, rate or extent of the regulated release of ecdysteroid from a cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0010488	biolink:NamedThing	UDP-galactose:N-glycan beta-1,3-galactosyltransferase activity	Catalysis of the reaction: UDP-galactose + N-glycan = galactose-beta-1,3-N-glycan + UDP.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0098009	biolink:NamedThing	viral terminase, large subunit	The part of the viral terminase complex that contains the translocase and endonuclease activities and allows the translocation of the phage DNA into the procapsid. The large subunit usually assembles as a heterooligomer with the small subunit.	tmpzr1t_l9r_go_relaxed.owl	virus terminase, large subunit					This term should only be used when the large subunit consists of more than one polypeptide.		bm	2012-07-25T10:13:00Z					cellular_component											owl:Class	
GO:0016576	biolink:NamedThing	histone dephosphorylation	The modification of histones by removal of phosphate groups.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0031627	biolink:NamedThing	telomeric loop formation	The process in which linear telomeric DNA is remodeled into duplex loops, by the invasion of a 3' single-stranded overhang into the duplex region.	tmpzr1t_l9r_go_relaxed.owl	T loop biosynthesis|t-loop formation|t-loop biosynthesis|T loop formation													biological_process											owl:Class	
GO:1905866	biolink:NamedThing	positive regulation of Atg1/ULK1 kinase complex assembly	Any process that activates or increases the frequency, rate or extent of Atg1/ULK1 kinase complex assembly.	tmpzr1t_l9r_go_relaxed.owl	up regulation of ULK1-ATG13-FIP200 complex assembly|up regulation of ATG1-ATG13 complex assembly|upregulation of ATG1-ATG13 complex formation|activation of ATG1 kinase complex assembly|activation of Atg1p signalling complex assembly|up regulation of ULK1 signaling complex assembly|up-regulation of ATG1/ULK1 kinase complex assembly|activation of ATG1 kinase complex formation|activation of ULK1 signaling complex formation|up-regulation of ATG1/ULK1 signaling complex assembly|up-regulation of ATG1 kinase complex assembly|positive regulation of ATG1 kinase complex assembly|up-regulation of ULK1-ATG13-FIP200 complex assembly|positive regulation of ATG1-ATG13 complex formation|upregulation of ULK1-ATG13-RB1CC1 complex formation|positive regulation of ATG1/ULK1 signaling complex assembly|up regulation of ULK1-ATG13-FIP200 complex formation|up-regulation of ATG1-ATG13 complex assembly|activation of ULK1-ATG13-RB1CC1 complex assembly|upregulation of ULK1-ATG13-FIP200 complex assembly|activation of ATG1/ULK1 signaling complex formation|upregulation of ATG1/ULK1 signaling complex assembly|up-regulation of Atg1p signalling complex formation|up-regulation of ULK1 signaling complex formation|positive regulation of ULK1-ATG13-RB1CC1 complex formation|upregulation of ATG1/ULK1 signaling complex formation|upregulation of ATG1/ULK1 kinase complex assembly|activation of ATG1-ATG13 complex formation|up regulation of Atg1p signalling complex formation|up regulation of ATG1/ULK1 signaling complex formation|upregulation of ATG1 kinase complex assembly|positive regulation of ATG1-ATG13 complex assembly|up-regulation of ULK1-ATG13-RB1CC1 complex assembly|activation of ATG1/ULK1 signaling complex assembly|upregulation of Atg1p signalling complex assembly|up regulation of ATG1 kinase complex formation|upregulation of ATG1 kinase complex formation|up regulation of ATG1/ULK1 signaling complex assembly|positive regulation of ULK1 signaling complex assembly|upregulation of ATG1/ULK1 kinase complex formation|upregulation of ATG1-ATG13 complex assembly|up-regulation of ULK1 signaling complex assembly|positive regulation of Atg1p signalling complex formation|upregulation of ULK1 signaling complex formation|up regulation of ULK1 signaling complex formation|positive regulation of ATG1 kinase complex formation|activation of Atg1p signalling complex formation|up regulation of ULK1-ATG13-RB1CC1 complex formation|activation of ATG1/ULK1 kinase complex formation|up-regulation of ATG1/ULK1 kinase complex formation|activation of ATG1/ULK1 kinase complex assembly|up-regulation of ATG1/ULK1 signaling complex formation|up regulation of ATG1/ULK1 kinase complex formation|positive regulation of ULK1-ATG13-FIP200 complex formation|up-regulation of ATG1-ATG13 complex formation|positive regulation of ATG1/ULK1 kinase complex formation|positive regulation of Atg1p signalling complex assembly|activation of ULK1-ATG13-FIP200 complex formation|positive regulation of ULK1-ATG13-FIP200 complex assembly|up regulation of Atg1p signalling complex assembly|activation of ULK1-ATG13-FIP200 complex assembly|up-regulation of ATG1 kinase complex formation|upregulation of Atg1p signalling complex formation|upregulation of ULK1-ATG13-RB1CC1 complex assembly|up-regulation of ULK1-ATG13-RB1CC1 complex formation|activation of ATG1-ATG13 complex assembly|positive regulation of ULK1 signaling complex formation|activation of ULK1-ATG13-RB1CC1 complex formation|up regulation of ULK1-ATG13-RB1CC1 complex assembly|positive regulation of ULK1-ATG13-RB1CC1 complex assembly|up regulation of ATG1-ATG13 complex formation|up regulation of ATG1 kinase complex assembly|activation of ULK1 signaling complex assembly|up-regulation of ULK1-ATG13-FIP200 complex formation|upregulation of ULK1 signaling complex assembly|positive regulation of ATG1/ULK1 signaling complex formation|upregulation of ULK1-ATG13-FIP200 complex formation|up-regulation of Atg1p signalling complex assembly|up regulation of ATG1/ULK1 kinase complex assembly							pr	2017-01-26T13:23:44Z					biological_process											owl:Class	
GO:0005416	biolink:NamedThing	amino acid:cation symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: amino acid(out) + cation(out) = amino acid(in) + cation(in).	tmpzr1t_l9r_go_relaxed.owl	cation:amino acid symporter activity|cation/amino acid symporter activity													molecular_function											owl:Class	
GO:0036143	biolink:NamedThing	kringle domain binding	Binding to a kringle domain. Kringle domains are protein domains that fold into large loops stabilized by 3 disulfide linkages, and are important in protein-protein interactions with blood coagulation factors.	tmpzr1t_l9r_go_relaxed.owl								bf	2012-03-09T09:49:43Z					molecular_function											owl:Class	
GO:0003697	biolink:NamedThing	single-stranded DNA binding	Binding to single-stranded DNA.	tmpzr1t_l9r_go_relaxed.owl	ssDNA binding					Note that this term is restricted to those cases where the binding is to a single-stranded DNA molecule, not to one of the stands of double-stranded DNA.						GO:0003699|GO:0003698		molecular_function											owl:Class	
GO:0004698	biolink:NamedThing	calcium-dependent protein kinase C activity	Calcium-dependent catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein.	tmpzr1t_l9r_go_relaxed.owl	calcium-dependent PKC activity|conventional protein kinase C activity				Reactome:R-HSA-416639|Reactome:R-HSA-114684|EC:2.7.11.13|Reactome:R-HSA-114683|Reactome:R-HSA-421007	This reaction requires diacylglycerol and calcium.								molecular_function											owl:Class	
GO:0009931	biolink:NamedThing	calcium-dependent protein serine/threonine kinase activity	Calcium-dependent catalysis of the reactions: ATP + a protein serine = ADP + protein serine phosphate; and ATP + a protein threonine = ADP + protein threonine phosphate.	tmpzr1t_l9r_go_relaxed.owl						These reactions are dependent on the presence of calcium ions.								molecular_function											owl:Class	
GO:0052781	biolink:NamedThing	chitobiose catabolic process	The chemical reactions and pathways resulting in the breakdown of any chitobiose, a family of compounds derived from chitin and based on the structure of D-glucosaminyl-(1->4)-D-glucosamine.	tmpzr1t_l9r_go_relaxed.owl								ai	2011-10-03T08:54:17Z					biological_process											owl:Class	
GO:0035571	biolink:NamedThing	N-terminal peptidyl-serine monomethylation	The monomethylation of the N-terminal serine of proteins to form the derivative N-methylserine.	tmpzr1t_l9r_go_relaxed.owl								bf	2010-08-06T01:58:56Z					biological_process											owl:Class	
GO:1901070	biolink:NamedThing	guanosine-containing compound biosynthetic process	The chemical reactions and pathways resulting in the formation of guanosine-containing compounds (guanosines).	tmpzr1t_l9r_go_relaxed.owl	guanosine-containing compound biosynthesis|guanosines anabolism|guanosines biosynthetic process|guanosines formation|guanosines synthesis|guanosine-containing compound synthesis|guanosine-containing compound anabolism|guanosines biosynthesis|guanosine-containing compound formation							bf	2012-07-02T01:52:09Z					biological_process											owl:Class	
GO:1900162	biolink:NamedThing	negative regulation of phospholipid scramblase activity	Any process that stops, prevents or reduces the frequency, rate or extent of phospholipid scramblase activity.	tmpzr1t_l9r_go_relaxed.owl	downregulation of phospholipid scramblase activity|inhibition of phospholipid scramblase activity|down-regulation of phospholipid scramblase activity|down regulation of phospholipid scramblase activity							rph	2012-03-08T10:57:23Z					biological_process											owl:Class	
GO:1905093	biolink:NamedThing	cellular response to diosgenin	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diosgenin stimulus.	tmpzr1t_l9r_go_relaxed.owl								bc	2016-03-31T11:04:38Z					biological_process											owl:Class	
GO:0032887	biolink:NamedThing	regulation of spindle elongation	Any process that modulates the frequency, rate or extent of the cell cycle process in which the distance is lengthened between poles of the spindle.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0014739	biolink:NamedThing	positive regulation of muscle hyperplasia	Any process that activates or increases the frequency, rate or extent of muscle hyperplasia.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0140042	biolink:NamedThing	lipid droplet formation	A process that results in the assembly, arrangement of constituent parts of a lipid droplet.	tmpzr1t_l9r_go_relaxed.owl	lipid body formation|lipid particle formation|adiposome formation							pg	2017-06-19T09:18:43Z					biological_process											owl:Class	
GO:0015735	biolink:NamedThing	uronic acid transmembrane transport	The process in which uronic acid is transported across a lipid bilayer, from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	uronic acid transport													biological_process											owl:Class	
GO:0045904	biolink:NamedThing	negative regulation of translational termination	Any process that stops, prevents, or reduces the frequency, rate or extent of translational termination.	tmpzr1t_l9r_go_relaxed.owl	downregulation of translational termination|inhibition of translational termination|down-regulation of translational termination|down regulation of translational termination													biological_process											owl:Class	
GO:1901725	biolink:NamedThing	regulation of histone deacetylase activity	Any process that modulates the frequency, rate or extent of histone deacetylase activity.	tmpzr1t_l9r_go_relaxed.owl								rl	2013-01-07T09:14:12Z					biological_process											owl:Class	
GO:0045477	biolink:NamedThing	regulation of nurse cell apoptotic process	Any process that modulates the frequency, rate or extent of nurse cell apoptotic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of nurse cell apoptosis													biological_process											owl:Class	
GO:0098949	biolink:NamedThing	intrinsic component of postsynaptic endosome membrane	The component of the postsynaptic endosome membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.	tmpzr1t_l9r_go_relaxed.owl	intrinsic to postsynaptic endosome membrane													cellular_component											owl:Class	
GO:0099125	biolink:NamedThing	PAK family kinase-Sog2 complex	A protein kinase complex comprising a conserved PAK/GC/Ste20 family kinase, leucine rich repeat protein Sog2 family, which function as part of the cell shape network.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0047471	biolink:NamedThing	maltose alpha-D-glucosyltransferase activity	Catalysis of the reaction: maltose = trehalose.	tmpzr1t_l9r_go_relaxed.owl	maltose alpha-D-glucosylmutase activity|maltose glucosylmutase activity|trehalose synthase activity				MetaCyc:5.4.99.16-RXN|RHEA:15145|EC:5.4.99.16									molecular_function											owl:Class	
GO:0061526	biolink:NamedThing	acetylcholine secretion	The regulated release of acetylcholine by a cell.	tmpzr1t_l9r_go_relaxed.owl								dph	2013-06-21T15:40:39Z					biological_process											owl:Class	
GO:0072343	biolink:NamedThing	pancreatic stellate cell proliferation	The multiplication or reproduction of pancreatic stellate cells, resulting in the expansion of a pancreatic stellate cell population. Pancreatic stellate cells are found in the periacinar space of the exocrine pancreas and in perivascular and periductal regions of the pancreas, and have long cytoplasmic processes that encircle the base of the acinus.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-11-05T03:04:50Z					biological_process											owl:Class	
GO:0004377	biolink:NamedThing	GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity	Catalysis of the reaction: an alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-diphosphodolichol + 2 GDP-alpha-D-mannose = an alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-diphosphodolichol + 2 GDP + 2 H+. This reaction is the transfer of an alpha-D-mannosyl residue from GDP-mannose into lipid-linked oligosaccharide, forming an alpha-(1->2)-D-mannosyl-D-mannose linkage.	tmpzr1t_l9r_go_relaxed.owl	GDP-mannose:glycolipid 1,2-alpha-D-mannosyltransferase activity|GDP-D-mannose:D-Man-alpha-(1->3)-[D-Man-alpha-(1->6)]-D-Man-beta-(1->4)-D-GlcNAc-beta-(1->4)-D-GlcNAc-diphosphodolichol alpha-1,2-mannosyltransferase activity|oligosaccharide-lipid mannosyltransferase activity|GDP-mannose-oligosaccharide-lipid mannosyltransferase activity|glycolipid 2-alpha-mannosyltransferase activity|guanosine diphosphomannose-oligosaccharide-lipid mannosyltransferase activity				RHEA:29523|EC:2.4.1.131|MetaCyc:2.4.1.131-RXN									molecular_function											owl:Class	
GO:0010422	biolink:NamedThing	regulation of brassinosteroid biosynthetic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of brassinosteroids.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0046467	biolink:NamedThing	membrane lipid biosynthetic process	The chemical reactions and pathways resulting in the formation of membrane lipids, any lipid found in or associated with a biological membrane.	tmpzr1t_l9r_go_relaxed.owl	membrane lipid formation|membrane lipid biosynthesis|membrane lipid anabolism|membrane lipid synthesis													biological_process											owl:Class	
GO:0006643	biolink:NamedThing	membrane lipid metabolic process	The chemical reactions and pathways involving membrane lipids, any lipid found in or associated with a biological membrane.	tmpzr1t_l9r_go_relaxed.owl	membrane lipid metabolism													biological_process											owl:Class	
GO:1901937	biolink:NamedThing	beta-caryophyllene biosynthetic process	The chemical reactions and pathways resulting in the formation of beta-caryophyllene.	tmpzr1t_l9r_go_relaxed.owl	beta-caryophyllene formation|beta-caryophyllene synthesis|beta-caryophyllene biosynthesis|beta-caryophyllene anabolism							ms	2013-02-18T14:55:18Z					biological_process											owl:Class	
GO:0043657	biolink:NamedThing	host cell	A cell within a host organism. Includes the host plasma membrane and any external encapsulating structures such as the host cell wall and cell envelope.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/19800												cellular_component											owl:Class	
GO:0018995	biolink:NamedThing	host cellular component	Any cellular component of a host cell. The host is an organism in which another organism, for instance a parasite or symbiont, spends part or all of its life cycle and from which it obtains nourishment and/or protection.	tmpzr1t_l9r_go_relaxed.owl	host organism				Wikipedia:Host_(biology)									cellular_component											owl:Class	
GO:0003067	biolink:NamedThing	circadian regulation of systemic arterial blood pressure by hormone	The process in which hormones modulate the force with which blood passes through the circulatory system contributing to different values of blood pressure oscillating with a regularity of approximately 24 hours. A hormone is one of a group of substances formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells, in the same organism, upon which they have a specific regulatory action.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0001990	biolink:NamedThing	regulation of systemic arterial blood pressure by hormone	The process in which hormones modulate the force with which blood passes through the circulatory system. A hormone is one of a group of substances formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells, in the same organism, upon which they have a specific regulatory action.	tmpzr1t_l9r_go_relaxed.owl	hormonal control of blood pressure|hormonal regulation of blood pressure|blood pressure regulation by hormone													biological_process											owl:Class	
GO:0043240	biolink:NamedThing	Fanconi anaemia nuclear complex	A protein complex composed of the Fanconi anaemia (FA) proteins including A, C, E, G and F (FANCA-F). Functions in the activation of the downstream protein FANCD2 by monoubiquitylation, and is essential for protection against chromosome breakage.	tmpzr1t_l9r_go_relaxed.owl	FA complex|Fanconi anaemia complex|FA core complex|FA nuclear complex													cellular_component											owl:Class	
GO:0004441	biolink:NamedThing	inositol-1,4-bisphosphate 1-phosphatase activity	Catalysis of the reaction: 1D-myo-inositol 1,4-bisphosphate + H2O = 1D-myo-inositol 4-phosphate + phosphate.	tmpzr1t_l9r_go_relaxed.owl	inositol polyphosphate 1-phosphatase activity|inositol-polyphosphate 1-phosphatase activity|1D-myo-inositol-1,4-bisphosphate 1-phosphohydrolase activity				RHEA:15553|EC:3.1.3.57|Reactome:R-HSA-1855208|MetaCyc:3.1.3.57-RXN									molecular_function											owl:Class	
GO:0016312	biolink:NamedThing	inositol bisphosphate phosphatase activity	Catalysis of the reaction: myo-inositol bisphosphate + H2O = myo-inositol phosphate + phosphate.	tmpzr1t_l9r_go_relaxed.owl					RHEA:57840|Reactome:R-HSA-6809565|Reactome:R-HSA-6809561									molecular_function											owl:Class	
GO:0015170	biolink:NamedThing	propanediol transmembrane transporter activity	Enables the transfer of propanediol from one side of a membrane to the other. Propanediol is a sweet colorless, viscous, hygroscopic liquid used as an antifreeze and in brake fluid; it is also as a humectant in cosmetics and personal care items, although it can be absorbed through the skin with harmful effects.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0048621	biolink:NamedThing	post-embryonic digestive tract morphogenesis	The process, occurring during the post-embryonic phase, by which the anatomical structures of the digestive tract are generated and organized. The digestive tract is the anatomical structure through which food passes and is processed.	tmpzr1t_l9r_go_relaxed.owl	post-embryonic gut morphogenesis													biological_process											owl:Class	
GO:1901517	biolink:NamedThing	aspyridone A catabolic process	The chemical reactions and pathways resulting in the breakdown of aspyridone A.	tmpzr1t_l9r_go_relaxed.owl	aspyridone A breakdown|aspyridone A catabolism|aspyridone A degradation							di	2012-10-18T18:31:32Z					biological_process											owl:Class	
GO:0010338	biolink:NamedThing	leaf formation	The process that gives rise to a leaf. This process pertains to the initial formation of a structure from unspecified parts.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0060231	biolink:NamedThing	mesenchymal to epithelial transition	A transition where a mesenchymal cell establishes apical/basolateral polarity, forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell.	tmpzr1t_l9r_go_relaxed.owl	epithelial cell differentiation from mesenchymal cell|mesenchymal-epithelial transition													biological_process											owl:Class	
GO:0060464	biolink:NamedThing	lung lobe formation	The developmental process pertaining to the initial formation of a lung lobe from unspecified parts. This process begins with the specific processes that contribute to the appearance of the lobe and ends when the structural rudiment is recognizable. A lung lobe is a projection that extends from the lung.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0070374	biolink:NamedThing	positive regulation of ERK1 and ERK2 cascade	Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the ERK1 and ERK2 cascade.	tmpzr1t_l9r_go_relaxed.owl	stimulation of ERK1 and ERK2 cascade|positive regulation of ERK cascade|positive regulation of MAPK3 cascade|positive regulation of ERK1 and ERK2 signaling pathway|up-regulation of ERK1 and ERK2 cascade|up regulation of ERK1 and ERK2 cascade|positive regulation of ERK1 and ERK2 signalling pathway|positive regulation of ERK1 cascade|upregulation of ERK1 and ERK2 cascade|activation of ERK1 and ERK2 cascade|positive regulation of ERK2 cascade|positive regulation of MAPK1 cascade|positive regulation of ERK1/2 cascade													biological_process											owl:Class	
GO:1902350	biolink:NamedThing	cellular response to chloroquine	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chloroquine stimulus.	tmpzr1t_l9r_go_relaxed.owl								kmv	2013-08-13T19:29:33Z					biological_process											owl:Class	
GO:1902349	biolink:NamedThing	response to chloroquine	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chloroquine stimulus.	tmpzr1t_l9r_go_relaxed.owl								kmv	2013-08-13T19:29:25Z					biological_process											owl:Class	
GO:0031500	biolink:NamedThing	Tea1 cell-end complex	A high molecular weight complex characterized in S. pombe containing the cell-end anchoring protein Tea1. This complex is transported to the cell ends by microtubules and is involved in bipolar growth and the maintennce of normal cell polarity.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0051984	biolink:NamedThing	positive regulation of chromosome segregation	Any process that activates or increases the frequency, rate or extent of chromosome segregation, the process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets.	tmpzr1t_l9r_go_relaxed.owl	activation of chromosome segregation|up-regulation of chromosome segregation|stimulation of chromosome segregation|upregulation of chromosome segregation|up regulation of chromosome segregation													biological_process											owl:Class	
GO:0051378	biolink:NamedThing	serotonin binding	Binding to serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties.	tmpzr1t_l9r_go_relaxed.owl	5-hydroxytryptamine binding													molecular_function											owl:Class	
GO:0090714	biolink:NamedThing	innate immunity memory response	An immune response mediated by the innate immune system and directed against a previously encountered immunologic stimulus, being quicker and quantitatively better compared with the initial response to that stimulus.	tmpzr1t_l9r_go_relaxed.owl								tb	2016-11-11T12:23:03Z					biological_process											owl:Class	
GO:0070583	biolink:NamedThing	spore membrane bending pathway	The process in which a bending force is generated in the prospore membrane to form the characteristic curved shape of the prospore.	tmpzr1t_l9r_go_relaxed.owl	FSM bending|ascospore-type prospore membrane bending|forespore membrane bending							mah	2009-04-24T10:48:09Z					biological_process											owl:Class	
GO:0006161	biolink:NamedThing	deoxyguanosine catabolic process	The chemical reactions and pathways resulting in the breakdown of deoxyguanosine, a nucleoside consisting of the base guanine and the sugar deoxyribose.	tmpzr1t_l9r_go_relaxed.owl	deoxyguanosine catabolism|deoxyguanosine degradation|deoxyguanosine breakdown													biological_process											owl:Class	
GO:0042453	biolink:NamedThing	deoxyguanosine metabolic process	The chemical reactions and pathways involving deoxyguanosine, a nucleoside consisting of the base guanine and the sugar deoxyribose.	tmpzr1t_l9r_go_relaxed.owl	deoxyguanosine metabolism													biological_process											owl:Class	
GO:0050949	biolink:NamedThing	negative regulation of late stripe melanocyte differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of late stripe melanocyte differentiation.	tmpzr1t_l9r_go_relaxed.owl	inhibition of late stripe melanocyte differentiation|downregulation of late stripe melanocyte differentiation|negative regulation of late stripe melanophore differentiation|down regulation of late stripe melanocyte differentiation|down-regulation of late stripe melanocyte differentiation													biological_process											owl:Class	
GO:1902696	biolink:NamedThing	glycine catabolic process to isobutanol	The chemical reactions and pathways resulting in the breakdown of glycine to isobutanol.	tmpzr1t_l9r_go_relaxed.owl	glycine breakdown to isobutanol|glycine catabolism to isobutanol|glycine degradation to isobutanol							tb	2014-02-19T18:00:12Z			GO:1990293		biological_process											owl:Class	
GO:0009954	biolink:NamedThing	proximal/distal pattern formation	The regionalization process in which specific areas of cell differentiation are determined along a proximal/distal axis. The proximal/distal axis is defined by a line that runs from main body (proximal end) of an organism outward (distal end).	tmpzr1t_l9r_go_relaxed.owl	proximal/distal pattern specification													biological_process											owl:Class	
GO:0070236	biolink:NamedThing	negative regulation of activation-induced cell death of T cells	Any process that stops, prevents, or reduces the frequency, rate or extent of activation-induced cell death of T cells.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of activation-induced cell death of T lymphocytes|negative regulation of antigen-driven apoptosis|negative regulation of activation-induced cell death of T-lymphocytes|inhibition of activation-induced cell death of T cells|negative regulation of activated T cell apoptosis|down regulation of activation-induced cell death of T cells|negative regulation of activation-induced cell death of T-cells|downregulation of activation-induced cell death of T cells|down-regulation of activation-induced cell death of T cells|negative regulation of AICD													biological_process											owl:Class	
GO:0033508	biolink:NamedThing	glutamate catabolic process to butyrate	The chemical reactions and pathways resulting in the breakdown of glutamate into other compounds, including butyrate.	tmpzr1t_l9r_go_relaxed.owl	glutamate degradation to butyrate|glutamate breakdown to butyrate				MetaCyc:PWY-5087									biological_process											owl:Class	
GO:0019605	biolink:NamedThing	butyrate metabolic process	The chemical reactions and pathways involving any butyrate, the anions of butyric acid (butanoic acid), a saturated, unbranched aliphatic acid.	tmpzr1t_l9r_go_relaxed.owl	butyrate metabolism|butyric acid metabolism|butanoic acid metabolic process|butyric acid metabolic process|butanoic acid metabolism											GO:0043437		biological_process											owl:Class	
GO:0046601	biolink:NamedThing	positive regulation of centriole replication	Any process that activates or increases the frequency, rate or extent of centriole replication.	tmpzr1t_l9r_go_relaxed.owl	up regulation of centriole replication|stimulation of centriole replication|up-regulation of centriole replication|upregulation of centriole replication|activation of centriole replication													biological_process											owl:Class	
GO:0035470	biolink:NamedThing	positive regulation of vascular wound healing	Any process that increases the rate, frequency, or extent of blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels and contribute to the series of events that restore integrity to damaged vasculature.	tmpzr1t_l9r_go_relaxed.owl								bf	2010-04-22T10:49:09Z					biological_process											owl:Class	
GO:0005229	biolink:NamedThing	intracellular calcium activated chloride channel activity	Enables the transmembrane transfer of chloride by a channel that opens in response to stimulus by a calcium ion or ions. Transport by a channel involves catalysis of facilitated diffusion of a solute (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel, without evidence for a carrier-mediated mechanism.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-9659568|Reactome:R-HSA-2684901|Reactome:R-HSA-2744361|Reactome:R-HSA-2744242									molecular_function											owl:Class	
GO:0061778	biolink:NamedThing	intracellular chloride channel activity	Enables the transmembrane transfer of chloride across the membrane of an intracellular compartment. Transport by a channel involves catalysis of facilitated diffusion of a solute (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel, without evidence for a carrier-mediated mechanism.	tmpzr1t_l9r_go_relaxed.owl								dph	2016-08-02T09:37:15Z					molecular_function											owl:Class	
GO:0071611	biolink:NamedThing	granulocyte colony-stimulating factor production	The appearance of granulocyte colony-stimulating factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	tmpzr1t_l9r_go_relaxed.owl	lenograstim production|filgrastim production|pluripoietin production|granulocyte colony stimulating factor production|G-CSF production|colony stimulating factor 3 (granulocyte) production|CSF3 production							mah	2010-02-05T04:38:11Z					biological_process											owl:Class	
GO:0071227	biolink:NamedThing	cellular response to molecule of oomycetes origin	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by molecules of oomycetes origin.	tmpzr1t_l9r_go_relaxed.owl	cellular response to oomycetes associated molecule							mah	2009-12-03T01:55:09Z					biological_process											owl:Class	
GO:0002240	biolink:NamedThing	response to molecule of oomycetes origin	Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by molecules of oomycetes origin.	tmpzr1t_l9r_go_relaxed.owl	response to oomycetes associated molecule													biological_process											owl:Class	
GO:0030740	biolink:NamedThing	inositol 3-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine(1+) + myo-inositol = 1D-3-O-methyl-myo-inositol + S-adenosyl-L-homocysteine + H(+).	tmpzr1t_l9r_go_relaxed.owl	myo-inositol 1-O-methyltransferase activity|S-adenosyl-L-methionine:myo-inositol 1-O-methyltransferase activity|myo-inositol 1-methyltransferase activity|myo-inositol 1-O-methyltransferase (name based on 1L-numbering system and not 1D-numbering)|S-adenosyl-L-methionine:1D-myo-inositol 3-O-methyltransferase activity|inositol L-1-methyltransferase activity|S-adenosylmethionine:myo-inositol 1-methyltransferase activity				RHEA:18877|MetaCyc:MYO-INOSITOL-1-O-METHYLTRANSFERASE-RXN|KEGG_REACTION:R01189|EC:2.1.1.39									molecular_function											owl:Class	
GO:0097445	biolink:NamedThing	presynaptic active zone dense projection	Electron dense projection extending from the cytomatrix into the cytoplasm on which synaptic vesicles are tethered.	tmpzr1t_l9r_go_relaxed.owl	pre-synaptic active zone dense projection|active zone dense projection				NIF_Subcellular:sao494258938			pr	2012-12-06T14:08:21Z					cellular_component											owl:Class	
GO:2001174	biolink:NamedThing	negative regulation of histone H2B conserved C-terminal lysine ubiquitination	Any process that stops, prevents or reduces the frequency, rate or extent of histone H2B conserved C-terminal lysine ubiquitination.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of budding yeast H2B K123 ubiquitination|negative regulation of fission yeast H2B K119 ubiquitination|negative regulation of mammalian H2B K120 ubiquitination							se	2011-10-29T06:28:53Z					biological_process											owl:Class	
GO:0033003	biolink:NamedThing	regulation of mast cell activation	Any process that modulates the frequency, rate, or extent of mast cell activation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0009521	biolink:NamedThing	photosystem	A complex located in a photosynthetic membrane that consists of a photoreaction center associated with accessory pigments and electron carriers. Examples of this component are found in Arabidopsis thaliana and in photosynthetic bacterial and archaeal species.	tmpzr1t_l9r_go_relaxed.owl	reaction centre|reaction center				Wikipedia:Photosystem							GO:0030090		cellular_component											owl:Class	
GO:1901933	biolink:NamedThing	bicyclogermacrene catabolic process	The chemical reactions and pathways resulting in the breakdown of bicyclogermacrene.	tmpzr1t_l9r_go_relaxed.owl	bicyclogermacrene breakdown|bicyclogermacrene catabolism|bicyclogermacrene degradation							ms	2013-02-18T14:54:57Z					biological_process											owl:Class	
GO:0051763	biolink:NamedThing	sesquiterpene catabolic process	The chemical reactions and pathways resulting in the breakdown of sesquiterpenes, any of a class of terpenes of the formula C15H24 or a derivative of such a terpene.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0048026	biolink:NamedThing	positive regulation of mRNA splicing, via spliceosome	Any process that activates or increases the rate or extent of mRNA splicing via a spliceosomal mechanism.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of nuclear mRNA splicing, via spliceosome|activation of nuclear mRNA splicing, via spliceosome|up regulation of nuclear mRNA splicing via U2-type spliceosome|stimulation of nuclear mRNA splicing via U2-type spliceosome|positive regulation of pre-mRNA splicing|stimulation of nuclear mRNA splicing, via spliceosome|upregulation of nuclear mRNA splicing via U2-type spliceosome|activation of nuclear mRNA splicing via U2-type spliceosome|positive regulation of nuclear mRNA splicing, via spliceosome|positive regulation of nuclear mRNA splicing via U2-type spliceosome|up regulation of nuclear mRNA splicing, via spliceosome|up-regulation of nuclear mRNA splicing via U2-type spliceosome|upregulation of nuclear mRNA splicing, via spliceosome											GO:0035057		biological_process											owl:Class	
GO:0046042	biolink:NamedThing	ITP biosynthetic process	The chemical reactions and pathways resulting in the formation of ITP, inosine triphosphate.	tmpzr1t_l9r_go_relaxed.owl	ITP biosynthesis|ITP anabolism|ITP synthesis|ITP formation													biological_process											owl:Class	
GO:0071638	biolink:NamedThing	negative regulation of monocyte chemotactic protein-1 production	Any process that stops, prevents, or reduces the frequency, rate, or extent of production of monocyte chemotactic protein-1.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of MCP-1 production|negative regulation of CCL2 production							mah	2010-02-12T10:39:51Z					biological_process											owl:Class	
GO:0060589	biolink:NamedThing	nucleoside-triphosphatase regulator activity	Binds to and modulates the activity of an NTPase.	tmpzr1t_l9r_go_relaxed.owl	NTPase regulator activity							dph	2009-05-08T02:49:24Z					molecular_function											owl:Class	
GO:0050131	biolink:NamedThing	N-methyl-L-amino-acid oxidase activity	Catalysis of the reaction: an N-methyl-L-amino acid + H2O + O2 = an L-amino acid + formaldehyde + H2O2.	tmpzr1t_l9r_go_relaxed.owl	N-methyl-L-amino-acid:oxygen oxidoreductase (demethylating)|N-methylamino acid oxidase activity				EC:1.5.3.2|RHEA:11472|MetaCyc:N-METHYL-L-AMINO-ACID-OXIDASE-RXN									molecular_function											owl:Class	
GO:0019379	biolink:NamedThing	sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin)	The pathway by which inorganic sulfate is processed and incorporated into sulfated compounds, where the phosphoadenylyl sulfate reduction step is catalyzed by the enzyme phosphoadenylyl-sulfate reductase (thioredoxin) (EC:1.8.4.8).	tmpzr1t_l9r_go_relaxed.owl	sulphate assimilation, phosphoadenylyl sulphate reduction by a phosphoadenylyl-sulphate reductase (thioredoxin)				MetaCyc:SO4ASSIM-PWY									biological_process											owl:Class	
GO:0110127	biolink:NamedThing	phloem unloading	The process of unloading solutes that are produced in the source tissues, from the sieve tube or companion cell of the phloem into the sink tissues.	tmpzr1t_l9r_go_relaxed.owl								kmv	2018-09-07T21:33:07Z					biological_process											owl:Class	
GO:0010233	biolink:NamedThing	phloem transport	The directed movement of substances, into, out of or within the phloem during long distance transport between source and sink tissues.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0150068	biolink:NamedThing	positive regulation of tubulin deacetylase activity	Any process that activates or increases the frequency, rate or extent of tubulin deacetylase activity.	tmpzr1t_l9r_go_relaxed.owl								bc	2018-07-24T10:35:51Z					biological_process											owl:Class	
GO:0090044	biolink:NamedThing	positive regulation of tubulin deacetylation	Any process that increases the frequency, rate or extent of tubulin deacetylation. Tubulin deacetylation is the removal of an acetyl group from a protein amino acid.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-08-03T11:54:18Z					biological_process											owl:Class	
GO:1900339	biolink:NamedThing	regulation of methane biosynthetic process from formic acid	Any process that modulates the frequency, rate or extent of methane biosynthetic process from formic acid.	tmpzr1t_l9r_go_relaxed.owl								tt	2012-04-06T02:04:53Z					biological_process											owl:Class	
GO:0047710	biolink:NamedThing	bis(5'-adenosyl)-triphosphatase activity	Catalysis of the reaction: P(1),P(3)-bis(5'-adenosyl) triphosphate + H(2)O = ADP + AMP + 2 H(+).	tmpzr1t_l9r_go_relaxed.owl	P1,P3-bis(5'-adenosyl)-triphosphate adenylohydrolase activity|AP(3)Aase activity|AP(3)A hydrolase activity|diadenosine 5',5'''-P(1),P(3)-triphosphate hydrolase activity|dinucleosidetriphosphatase activity|1-P,3-P-bis(5'-adenosyl)-triphosphate adenylohydrolase activity|AP3A hydrolase activity|AP3Aase activity|diadenosine 5',5'''-P1,P3-triphosphate hydrolase activity|diadenosine 5,5-P1,P3-triphosphatase activity				MetaCyc:BIS5-ADENOSYL-TRIPHOSPHATASE-RXN|KEGG_REACTION:R00187|RHEA:13893|EC:3.6.1.29									molecular_function											owl:Class	
GO:0048056	biolink:NamedThing	R3/R4 cell differentiation	The process in which relatively unspecialized cells acquire the specialized features of R3 and R4 photoreceptors. An example of this process is found in Drosophila melanogaster.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0071626	biolink:NamedThing	mastication	The process of biting and mashing food with the teeth prior to swallowing.	tmpzr1t_l9r_go_relaxed.owl	chewing							mah	2010-02-10T11:19:48Z					biological_process											owl:Class	
GO:0004032	biolink:NamedThing	alditol:NADP+ 1-oxidoreductase activity	Catalysis of the reaction: an alditol + NADP+ = an aldose + NADPH + H+.	tmpzr1t_l9r_go_relaxed.owl	polyol dehydrogenase (NADP(+)) activity|aldehyde reductase activity|aldose reductase activity				EC:1.1.1.21|RHEA:12789|MetaCyc:ALDEHYDE-REDUCTASE-RXN|KEGG_REACTION:R02820|Reactome:R-HSA-5652172|Reactome:R-HSA-196060									molecular_function											owl:Class	
GO:0008106	biolink:NamedThing	alcohol dehydrogenase (NADP+) activity	Catalysis of the reaction: an alcohol + NADP+ = an aldehyde + NADPH + H+.	tmpzr1t_l9r_go_relaxed.owl	alcohol:NADP dehydrogenase activity|aldehyde reductase (NADPH) activity|aldehyde reductase (NADPH2) activity|NADP-aldehyde reductase activity				EC:1.1.1.2|MetaCyc:ALCOHOL-DEHYDROGENASE-NADP+-RXN|RHEA:15937									molecular_function											owl:Class	
GO:0030037	biolink:NamedThing	actin filament reorganization involved in cell cycle	The cell cycle process in which rearrangement of the spatial distribution of actin filaments and associated proteins occurs.	tmpzr1t_l9r_go_relaxed.owl	actin filament reorganization during cell cycle|actin filament reorganisation involved in cell cycle													biological_process											owl:Class	
GO:0009629	biolink:NamedThing	response to gravity	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gravitational stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to gravitational stimulus													biological_process											owl:Class	
GO:0030997	biolink:NamedThing	regulation of centriole-centriole cohesion	Any process that modulates the extent to which the two centrioles within a centrosome remain tightly paired; may be mediated by the assembly and disassembly of a proteinaceous linker.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0001710	biolink:NamedThing	mesodermal cell fate commitment	The cell differentiation process that results in commitment of a cell to become part of the mesoderm.	tmpzr1t_l9r_go_relaxed.owl	mesoderm cell fate commitment													biological_process											owl:Class	
GO:0102313	biolink:NamedThing	1,8-cineole synthase activity	Catalysis of the reaction: geranyl diphosphate(3-) + H2O <=> 1,8-cineole + diphosphoric acid.	tmpzr1t_l9r_go_relaxed.owl					EC:4.2.3.108|MetaCyc:RXN-12980|RHEA:32543									molecular_function											owl:Class	
GO:0022609	biolink:NamedThing	multicellular organism adhesion to substrate	The attachment of a multicellular organism to a surface or material.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0102703	biolink:NamedThing	camphene synthase activity	Catalysis of the reaction: geranyl diphosphate <=> (-)-camphene + diphosphoric acid.	tmpzr1t_l9r_go_relaxed.owl					RHEA:25484|MetaCyc:RXN-5142|EC:4.2.3.117									molecular_function											owl:Class	
GO:0003955	biolink:NamedThing	NAD(P)H dehydrogenase (quinone) activity	Catalysis of the reaction: NAD(P)H + H+ + a quinone = NAD(P)+ + a hydroquinone.	tmpzr1t_l9r_go_relaxed.owl	azoreductase activity|quinone reductase activity|NADH-menadione reductase activity|menadione reductase activity|NAD(P)H menadione reductase activity|reduced nicotinamide-adenine dinucleotide (phosphate) dehydrogenase activity|NAD(P)H: menadione oxidoreductase activity|reduced NAD(P)H dehydrogenase activity|dehydrogenase, reduced nicotinamide adenine dinucleotide (phosphate, quinone) activity|NQO1|vitamin K reductase activity|naphthoquinone reductase activity|NAD(P)H dehydrogenase activity|QR1|NAD(P)H(2) dehydrogenase (quinone) activity|p-benzoquinone reductase activity|phylloquinone reductase activity|NAD(P)H-quinone oxidoreductase activity|diaphorase activity|NAD(P)H:quinone oxidoreductase activity|NAD(P)H:(quinone-acceptor)oxidoreductase activity|menadione oxidoreductase activity|flavoprotein NAD(P)H-quinone reductase activity|NAD(P)H2 dehydrogenase (quinone)|DT-diaphorase activity|NAD(P)H-quinone dehydrogenase activity|vitamin-K reductase activity|viologen accepting pyridine nucleotide oxidoreductase activity				UM-BBD_reactionID:r0227|MetaCyc:NQOR-RXN|EC:1.6.5.2									molecular_function											owl:Class	
GO:1901852	biolink:NamedThing	7,8-didemethyl-8-hydroxy-5-deazariboflavin biosynthetic process	The chemical reactions and pathways resulting in the formation of 7,8-didemethyl-8-hydroxy-5-deazariboflavin.	tmpzr1t_l9r_go_relaxed.owl	coenzyme F0 biosynthesis|coenzyme F0 anabolism|coenzyme F0 biosynthetic process|7,8-didemethyl-8-hydroxy-5-deazariboflavin formation|7,8-didemethyl-8-hydroxy-5-deazariboflavin biosynthesis|coenzyme F0 formation|7,8-didemethyl-8-hydroxy-5-deazariboflavin synthesis|coenzyme F0 synthesis|7,8-didemethyl-8-hydroxy-5-deazariboflavin anabolism							yaf	2013-01-28T11:38:41Z					biological_process											owl:Class	
GO:0052659	biolink:NamedThing	inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity	Catalysis of the reaction: 1D-myo-inositol 1,3,4,5-tetrakisphosphate + H2O = 1D-myo-inositol 1,3,4-trisphosphate + phosphate.	tmpzr1t_l9r_go_relaxed.owl	type I inositol-polyphosphate phosphatase activity|Ins(1,3,4,5)P(4) 5-phosphatase activity|D-myo-inositol (1,3,4,5)-polyphosphate 5-phosphatase activity|inositol polyphosphate-5-phosphatase activity|type II inositol polyphosphate 5-phosphatase activity|5PTase activity|Ins(1,3,4,5)P4 5-phosphatase activity				Reactome:R-HSA-1855218|EC:3.1.3.56|Reactome:R-HSA-1855213|RHEA:11392|MetaCyc:RXN-8730|KEGG_REACTION:R03430									molecular_function											owl:Class	
GO:1990339	biolink:NamedThing	laminin-522 complex	A laminin complex composed of alpha5, beta2 and gamma2 polypeptide chains.	tmpzr1t_l9r_go_relaxed.owl	laminin-522							bhm	2014-03-20T23:41:32Z					cellular_component											owl:Class	
GO:0005705	biolink:NamedThing	polytene chromosome interband	A stretch of less tightly packed chromatin along the polytene chromosome, found between bands.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0010253	biolink:NamedThing	UDP-rhamnose biosynthetic process	The chemical reactions and pathways resulting in the formation of UDP-L-rhamnose, a substance composed of rhamnose in glycosidic linkage with uridine diphosphate.	tmpzr1t_l9r_go_relaxed.owl	UDP-rhamnose synthesis|UDP-rhamnose biosynthesis|UDP-rhamnose formation|UDP-rhamnose anabolism				MetaCyc:PWY-3261									biological_process											owl:Class	
GO:0035590	biolink:NamedThing	purinergic nucleotide receptor signaling pathway	The series of molecular signals generated as a consequence of a receptor binding to an extracellular purine nucleotide to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	purinoceptor signaling pathway|purinergic nucleotide receptor signalling pathway|purinergic receptor signaling pathway|purinergic receptor signalling pathway|P2 receptor signaling pathway							bf	2010-10-22T11:09:40Z			GO:0035587		biological_process											owl:Class	
GO:0003059	biolink:NamedThing	positive regulation of the force of heart contraction by epinephrine	The process in which the secretion of epinephrine into the bloodstream or released from nerve endings modulates the force of heart muscle contraction.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of heart contraction by adrenaline|adrenaline cardiac inotropy|adrenaline regulation of the strength of heart muscle contraction|increased force of heart contraction by epinephrine|positive regulation of heart contraction by epinephrine|epinephrine cardiac inotropy													biological_process											owl:Class	
GO:0044061	biolink:NamedThing	modulation by symbiont of host excretion	The alteration by a symbiont organism of the functioning of excretion, the elimination by the host organism of the waste products that arise as a result of metabolic activity.	tmpzr1t_l9r_go_relaxed.owl	regulation by symbiont of host excretion													biological_process											owl:Class	
GO:0071489	biolink:NamedThing	cellular response to red or far red light	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a red or far red light stimulus. Red light is electromagnetic radiation of wavelength of 580-700nm. Far red light is electromagnetic radiation of wavelength 700-800nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reversed by exposure to far red light. During the initial phase the phytochrome molecule is only present in the red light absorbing form, but on absorption of red light it changes to a far red light absorbing form, triggering progress through development. An immediate short period of exposure to far red light entirely returns the pigment to its initial state and prevents triggering of the developmental process. A thirty minute break between red and subsequent far red light exposure renders the red light effect irreversible, and development then occurs regardless of whether far red light exposure subsequently occurs.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-12-18T02:18:25Z					biological_process											owl:Class	
GO:2001118	biolink:NamedThing	tetrahydromethanopterin biosynthetic process	The chemical reactions and pathways resulting in the formation of a tetrahydromethanopterin.	tmpzr1t_l9r_go_relaxed.owl	tetrahydromethanopterin biosynthesis							jl	2011-10-11T12:13:19Z					biological_process											owl:Class	
GO:0019584	biolink:NamedThing	galactonate catabolic process	The chemical reactions and pathways resulting in the breakdown of galactonate, the anion of galactonic acid.	tmpzr1t_l9r_go_relaxed.owl	galactonate catabolism|galactonate breakdown|galactonate degradation				MetaCyc:GALACTCAT-PWY									biological_process											owl:Class	
GO:1903636	biolink:NamedThing	regulation of protein insertion into mitochondrial outer membrane	Any process that modulates the frequency, rate or extent of protein insertion into mitochondrial outer membrane.	tmpzr1t_l9r_go_relaxed.owl	regulation of protein transport into mitochondrial outer membrane|regulation of mitochondrial outer membrane protein import|regulation of protein import into mitochondrial outer membrane							pga	2014-11-20T15:54:44Z					biological_process											owl:Class	
GO:0061031	biolink:NamedThing	endodermal digestive tract morphogenesis	The process in which the anatomical structures of the endodermal digestive tract are generated and organized. The endodermal digestive tract includes those portions of the digestive tract that are derived from endoderm.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-02-09T09:46:43Z					biological_process											owl:Class	
GO:1901131	biolink:NamedThing	kanamycin metabolic process	The chemical reactions and pathways involving kanamycin.	tmpzr1t_l9r_go_relaxed.owl	kanamycin metabolism							yaf	2012-07-11T03:27:04Z					biological_process											owl:Class	
GO:0014708	biolink:NamedThing	regulation of somitomeric trunk muscle development	Any process that modulates the frequency, rate or extent of somitomeric trunk muscle development.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0048634	biolink:NamedThing	regulation of muscle organ development	Any process that modulates the frequency, rate or extent of muscle development.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0010672	biolink:NamedThing	regulation of transcription from RNA polymerase II promoter involved in meiotic cell cycle	Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter as part of the meiotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl	regulation of meiosis by regulation of transcription from RNA polymerase II promoter|regulation of transcription from RNA polymerase II promoter, meiotic							mah	2012-04-20T02:45:12Z			GO:1900401		biological_process											owl:Class	
GO:0061875	biolink:NamedThing	negative regulation of hepatic stellate cell contraction	Any process that modulates stops, prevents, or reduces the frequency, rate or extent of hepatic stellate cell contraction.	tmpzr1t_l9r_go_relaxed.owl								dph	2017-05-01T13:31:42Z					biological_process											owl:Class	
GO:0043837	biolink:NamedThing	valine dehydrogenase (NAD) activity	Catalysis of the reaction: L-valine + H2O + NAD+ = 3-methyl-2-oxobutanoate + NH3 + NADH.	tmpzr1t_l9r_go_relaxed.owl	ValDH				EC:1.4.1.23|RHEA:30763									molecular_function											owl:Class	
GO:0051351	biolink:NamedThing	positive regulation of ligase activity	Any process that activates or increases the frequency, rate or extent of ligase activity, the catalysis of the ligation of two substances with concomitant breaking of a diphosphate linkage, usually in a nucleoside triphosphate.	tmpzr1t_l9r_go_relaxed.owl	upregulation of ligase activity|activation of ligase activity|up-regulation of ligase activity|ligase activator|stimulation of ligase activity|up regulation of ligase activity													biological_process											owl:Class	
GO:0097472	biolink:NamedThing	cyclin-dependent protein kinase activity	Cyclin-dependent catalysis of the phosphorylation of an amino acid residue in a protein, usually according to the reaction: a protein + ATP = a phosphoprotein + ADP.	tmpzr1t_l9r_go_relaxed.owl						This reaction requires the binding of a regulatory cyclin subunit and full activity requires stimulatory phosphorylation by a CDK-activating kinase (CAK).		pr	2013-03-06T13:46:04Z					molecular_function											owl:Class	
GO:0120027	biolink:NamedThing	regulation of osmosensory signaling pathway	Any process that modulates the frequency, rate or extent of osmosensory signaling pathway.	tmpzr1t_l9r_go_relaxed.owl								krc	2017-03-31T14:45:01Z					biological_process											owl:Class	
GO:0010222	biolink:NamedThing	stem vascular tissue pattern formation	Vascular tissue pattern formation as it occurs in the stem of vascular plants.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0010051	biolink:NamedThing	xylem and phloem pattern formation	The regionalization process that gives rise to the patterning of the conducting tissues. An example of this process is found in Arabidopsis thaliana.	tmpzr1t_l9r_go_relaxed.owl	vascular tissue pattern formation													biological_process											owl:Class	
GO:0052850	biolink:NamedThing	NADPH-dependent dihydrocurcumin reductase activity	Catalysis of the reaction: dihydrocurcumin + NADPH+ + H+ = tetrahydrocurcumin + NADP+.	tmpzr1t_l9r_go_relaxed.owl	dihydrocurcumin reductase (NADPH) activity				MetaCyc:RXN0-6677			ai	2011-12-05T11:04:23Z					molecular_function											owl:Class	
GO:0034252	biolink:NamedThing	negative regulation of cellular amide catabolic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of amides.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of amide breakdown|negative regulation of amide catabolism|negative regulation of amide degradation													biological_process											owl:Class	
GO:0034251	biolink:NamedThing	regulation of cellular amide catabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of amides.	tmpzr1t_l9r_go_relaxed.owl	regulation of amide breakdown|regulation of amide degradation|regulation of amide catabolism													biological_process											owl:Class	
GO:0034307	biolink:NamedThing	regulation of ascospore formation	Any process that modulates the frequency, rate or extent of ascospore formation. An example of this process is found in Saccharomyces cerevisiae.	tmpzr1t_l9r_go_relaxed.owl	MAPKKK cascade during sporulation													biological_process											owl:Class	
GO:0007532	biolink:NamedThing	regulation of mating-type specific transcription, DNA-templated	Any mating-type specific process that modulates the frequency, rate or extent of cellular DNA-templated transcription.	tmpzr1t_l9r_go_relaxed.owl	regulation of mating-type specific transcription, DNA-dependent|mating-type specific transcriptional control													biological_process											owl:Class	
GO:0031407	biolink:NamedThing	oxylipin metabolic process	The chemical reactions and pathways involving any oxylipin, any of a group of biologically active compounds formed by oxidative metabolism of polyunsaturated fatty acids.	tmpzr1t_l9r_go_relaxed.owl	oxylipin metabolism													biological_process											owl:Class	
GO:0006452	biolink:NamedThing	translational frameshifting	A mechanism whereby different proteins may result from a single mRNA molecule, due to a change in the parsing of three nucleotides per codon relative to an initiating AUG codon.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Translational_frameshift									biological_process											owl:Class	
GO:0033433	biolink:NamedThing	AUU codon-amino acid adaptor activity	A triplet codon-amino acid adaptor activity that recognizes an AUU codon.	tmpzr1t_l9r_go_relaxed.owl	isoleucine tRNA|ATT codon-amino acid adaptor activity					Note that in the standard genetic code, ATT codes for isoleucine.								molecular_function											owl:Class	
GO:1990174	biolink:NamedThing	phosphodiesterase decapping endonuclease activity	Catalysis of the removal of the cap from an unmethylated 5'-end capped RNA resulting in the release of the entire cap structure (GpppN) and a 5' monophosphorylated RNA.	tmpzr1t_l9r_go_relaxed.owl	G(5')pppN pyrophosphatase activity							tb	2013-08-26T17:51:00Z					molecular_function											owl:Class	
GO:0010080	biolink:NamedThing	regulation of floral meristem growth	Any process involved in maintaining the size and shape of a floral meristem.	tmpzr1t_l9r_go_relaxed.owl	regulation of floral meristem size													biological_process											owl:Class	
GO:0031388	biolink:NamedThing	organic acid phosphorylation	The process of introducing one or more phosphate groups into an organic acid.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:2001085	biolink:NamedThing	arabinogalactan binding	Binding to arabinogalactan.	tmpzr1t_l9r_go_relaxed.owl								jl	2011-09-15T01:35:51Z					molecular_function											owl:Class	
GO:0018126	biolink:NamedThing	protein hydroxylation	The addition of a hydroxy group to a protein amino acid.	tmpzr1t_l9r_go_relaxed.owl	protein amino acid hydroxylation													biological_process											owl:Class	
GO:1905021	biolink:NamedThing	regulation of threonine-tRNA ligase activity	Any process that modulates the frequency, rate or extent of threonine-tRNA ligase activity.	tmpzr1t_l9r_go_relaxed.owl	regulation of threonyl-tRNA synthetase activity|regulation of threonine-transfer ribonucleate synthetase activity|regulation of threonine translase activity|regulation of L-threonine:tRNAThr ligase (AMP-forming)|regulation of threonyl-transfer RNA synthetase activity|regulation of threonyl-transfer ribonucleic acid synthetase activity|regulation of threonyl ribonucleic synthetase activity|regulation of TRS|regulation of threonyl-transfer ribonucleate synthetase activity							sl	2016-03-03T19:12:23Z					biological_process											owl:Class	
GO:0010497	biolink:NamedThing	plasmodesmata-mediated intercellular transport	The movement of substances between cells via plasmodesmata. Plasmodesmata is a fine cytoplasmic channel, found in all higher plants, that connects the cytoplasm of one cell to that of an adjacent cell.	tmpzr1t_l9r_go_relaxed.owl	plasmodesma-mediated cell-to-cell transport|plasmodesmata-mediated cell-to-cell transport|single organism plasmodesmata-mediated intercellular transport|plasmodesma-mediated intercellular transport|single-organism plasmodesmata-mediated intercellular transport							jl	2013-12-19T13:37:36Z			GO:1902587		biological_process											owl:Class	
GO:0010496	biolink:NamedThing	intercellular transport	The movement of substances between cells.	tmpzr1t_l9r_go_relaxed.owl	single-organism intercellular transport|single organism intercellular transport							jl	2013-12-19T13:24:56Z			GO:1902585		biological_process											owl:Class	
GO:0102809	biolink:NamedThing	delphinidin 3-O-glucoside 2''-O-glucosyltransferase activity	Catalysis of the reaction: UDP-alpha-D-glucose + delphinidin 3-O-beta-D-glucoside <=> H+ + delphinidin 3-O-sophoroside + UDP.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-8178									molecular_function											owl:Class	
GO:0036499	biolink:NamedThing	PERK-mediated unfolded protein response	A series of molecular signals mediated by the endoplasmic reticulum membrane stress sensor PERK (PKR-like ER kinase). Begins with activation of PERK in response to endoplasmic reticulum (ER) stress and ends with regulation of a downstream cellular process, e.g. transcription. The main substrate of PERK is the translation initiation factor eIF2alpha. Serine-phosphorylation of eIF2alpha by PERK inactivates eIF2alpha and inhibits general protein translation. In addition, eIF2alpha phosphorylation preferentially increases the translation of selective mRNAs such as ATF4 (activating transcription factor 4), which up regulates a subset of UPR genes required to restore folding capacity.	tmpzr1t_l9r_go_relaxed.owl	PKR-like ER kinase signal transduction|UPR signaling by PERK stress sensor|PERK branch of UPR|PERK signaling in response to endoplasmic reticulum stress|eukaryotic translation initiation factor 2-alpha kinase 3-mediated unfolded protein response|endoplasmic reticulum unfolded protein response; PERK signaling|EIF2AK3-mediated unfolded protein response|PERK signal transduction pathway							bf	2015-02-05T13:17:43Z					biological_process											owl:Class	
GO:0031587	biolink:NamedThing	positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity	Any process that activates or increases the frequency, rate or extent of the activity of the inositol 1,4,5-trisphosphate-sensitive calcium-release channel.	tmpzr1t_l9r_go_relaxed.owl	up regulation of IP3 receptor activity|upregulation of IP3 receptor activity|activation of IP3 receptor activity|positive regulation of inositol-1,4,5-trisphosphate receptor activity|up-regulation of IP3 receptor activity|stimulation of IP3 receptor activity|positive regulation of IP3 receptor activity													biological_process											owl:Class	
GO:2001187	biolink:NamedThing	positive regulation of CD8-positive, alpha-beta T cell activation	Any process that activates or increases the frequency, rate or extent of CD8-positive, alpha-beta T cell activation.	tmpzr1t_l9r_go_relaxed.owl								yaf	2011-11-03T01:17:02Z					biological_process											owl:Class	
GO:0045578	biolink:NamedThing	negative regulation of B cell differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of B cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of B cell development|negative regulation of B-cell differentiation|down-regulation of B cell differentiation|negative regulation of B-lymphocyte differentiation|inhibition of B cell differentiation|down regulation of B cell differentiation|negative regulation of B lymphocyte differentiation|downregulation of B cell differentiation					Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.								biological_process											owl:Class	
GO:0071033	biolink:NamedThing	nuclear retention of pre-mRNA at the site of transcription	The process involved in retention of aberrant or improperly formed mRNAs, e.g. those that are incorrectly or incompletely spliced or that have incorrectly formed 3'-ends, within the nucleus at the site of transcription.	tmpzr1t_l9r_go_relaxed.owl								krc	2009-07-28T04:35:54Z					biological_process											owl:Class	
GO:0097213	biolink:NamedThing	regulation of lysosomal membrane permeability	Any process that modulates the frequency, rate or extent of the passage or uptake of molecules by the lysosomal membrane.	tmpzr1t_l9r_go_relaxed.owl	regulation of lysosome membrane permeability							pr	2012-01-12T10:19:44Z					biological_process											owl:Class	
GO:0051095	biolink:NamedThing	regulation of helicase activity	Any process that modulates the frequency, rate or extent of helicase activity.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0045807	biolink:NamedThing	positive regulation of endocytosis	Any process that activates or increases the frequency, rate or extent of endocytosis.	tmpzr1t_l9r_go_relaxed.owl	upregulation of endocytosis|stimulation of endocytosis|up-regulation of endocytosis|up regulation of endocytosis|activation of endocytosis													biological_process											owl:Class	
GO:0016504	biolink:NamedThing	peptidase activator activity	Binds to and increases the activity of a peptidase, any enzyme that catalyzes the hydrolysis peptide bonds.	tmpzr1t_l9r_go_relaxed.owl	protease activator activity				Reactome:R-HSA-168865									molecular_function											owl:Class	
GO:2000883	biolink:NamedThing	positive regulation of starch catabolic process	Any process that activates or increases the frequency, rate or extent of starch catabolic process.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of starch breakdown|positive regulation of starch catabolism|positive regulation of starch degradation							bf	2011-07-27T03:23:51Z					biological_process											owl:Class	
GO:2000906	biolink:NamedThing	positive regulation of starch metabolic process	Any process that activates or increases the frequency, rate or extent of starch metabolic process.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of starch metabolism							tb	2011-07-28T11:33:19Z					biological_process											owl:Class	
GO:0019885	biolink:NamedThing	antigen processing and presentation of endogenous peptide antigen via MHC class I	The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class I protein complex. The peptide antigen is typically, but not always, processed from a whole protein. Class I here refers to classical class I molecules.	tmpzr1t_l9r_go_relaxed.owl	endogenous peptide antigen processing and presentation via MHC class I|antigen presentation, endogenous peptide antigen|antigen processing, endogenous antigen via MHC class I|antigen processing, endogenous antigen via major histocompatibility complex class I											GO:0048004		biological_process											owl:Class	
GO:0032325	biolink:NamedThing	molybdopterin cofactor catabolic process	The chemical reactions and pathways resulting in the breakdown of the molybdopterin cofactor (Moco), essential for the catalytic activity of some enzymes, e.g. sulfite oxidase, xanthine dehydrogenase, and aldehyde oxidase. The cofactor consists of a mononuclear molybdenum (Mo-molybdopterin) or tungsten ion (W-molybdopterin) coordinated by one or two molybdopterin ligands.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0043326	biolink:NamedThing	chemotaxis to folate	The directed movement of a motile cell or organism in response to the presence of folate.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0009261	biolink:NamedThing	ribonucleotide catabolic process	The chemical reactions and pathways resulting in the breakdown of a ribonucleotide, a compound consisting of ribonucleoside (a base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.	tmpzr1t_l9r_go_relaxed.owl	ribonucleotide catabolism|ribonucleotide degradation|ribonucleotide breakdown													biological_process											owl:Class	
GO:0051966	biolink:NamedThing	regulation of synaptic transmission, glutamatergic	Any process that modulates the frequency, rate or extent of glutamatergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glutamate.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0009381	biolink:NamedThing	excinuclease ABC activity	Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acid at sites flanking regions of damaged DNA to which the Uvr ABC excinuclease complexes bind.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0010037	biolink:NamedThing	response to carbon dioxide	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbon dioxide (CO2) stimulus.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0046097	biolink:NamedThing	deoxyuridine biosynthetic process	The chemical reactions and pathways resulting in the formation of deoxyuridine, 2-deoxyribosyluracil, one of the four major nucleosides of DNA.	tmpzr1t_l9r_go_relaxed.owl	deoxyuridine biosynthesis|deoxyuridine formation|deoxyuridine anabolism|deoxyuridine synthesis													biological_process											owl:Class	
GO:1901742	biolink:NamedThing	2-deoxystreptamine metabolic process	The chemical reactions and pathways involving 2-deoxystreptamine.	tmpzr1t_l9r_go_relaxed.owl	2-deoxystreptamine metabolism							yaf	2013-01-14T10:01:57Z					biological_process											owl:Class	
GO:0045322	biolink:NamedThing	unmethylated CpG binding	Binding to uan nmethylated CpG motif. Unmethylated CpG dinucleotides are often associated with gene promoters.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0015174	biolink:NamedThing	basic amino acid transmembrane transporter activity	Enables the transfer of basic amino acids from one side of a membrane to the other. Basic amino acids have side chains with a positive charge at pH 7.3.	tmpzr1t_l9r_go_relaxed.owl	basic amino acid transporter activity|basic amino acid permease activity|cationic amino acid transmembrane transporter activity				Reactome:R-HSA-8932851|Reactome:R-HSA-8959781							GO:0005286|GO:0015326		molecular_function											owl:Class	
GO:0039529	biolink:NamedThing	RIG-I signaling pathway	Any series of molecular signals generated as a consequence of the cytoplasmic pattern recognition receptor (PRR) RIG-1 (also known as DDX58) binding to viral RNA. RIG-I detects RNA synthesized during active viral replication and triggers a signaling pathway to protect the host against viral infection, for example by inducing the expression of antiviral cytokines.	tmpzr1t_l9r_go_relaxed.owl	RIG-I signalling pathway|retinoic acid inducible gene I signaling pathway|DDX58 signaling pathway					The apoptosis effect triggered by the RIG-I signaling pathway is inconclusive and may represent an in-vitro phenomenon. Therefore, in GO the term 'RIG-I signaling pathway ; GO:0039529' is positioned under 'regulation of cytokine production' as this is its primary effect.		bf	2011-12-20T03:11:06Z					biological_process											owl:Class	
GO:0039528	biolink:NamedThing	cytoplasmic pattern recognition receptor signaling pathway in response to virus	Any series of molecular signals generated as a consequence of a virus or viral RNA binding to a pattern recognition receptor (PRR) located in the cytoplasm. Cytosolic PRRs such as RIG-I (DDX58) and MDA-5 (IFIH1) detect RNA synthesized during active viral replication and trigger a signaling pathway to protect the host against viral infection, for example by inducing the expression of antiviral cytokines.	tmpzr1t_l9r_go_relaxed.owl	RIG-I/MDA5 signaling pathway|cytoplasmic caspase-recruiting domain (CARD) helicase signaling pathway|RIG-I-like receptor (RLR) signaling pathway|RLR signaling pathway|cytoplasmic pattern recognition receptor signalling pathway in response to virus|RLH signaling pathway|RIG-like helicase signaling pathway|RIG-like receptor signaling pathway|virus-induced cytoplasmic pattern recognition receptor signaling pathway					This term should be used for annotation when it is not known which cytoplasmic pattern recognition receptor (PRR) has detected the viral RNA. If the PRR is known, consider instead the child terms. The RIG-like family is composed of at least RIG-I (retinoic acid inducible gene I; also known as DDX58), melanoma differentiation-associated gene 5 (MDA5; also known as helicard or IFIH1) and LGP2.		bf	2011-12-20T02:43:15Z					biological_process											owl:Class	
GO:0044628	biolink:NamedThing	positive regulation of complement activation, classical pathway in other organism	Any process that activates or increases the frequency, rate or extent of complement activation by the classical pathway, in a different organism.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-07-05T01:00:10Z					biological_process											owl:Class	
GO:0034138	biolink:NamedThing	toll-like receptor 3 signaling pathway	Any series of molecular signals generated as a consequence of binding to toll-like receptor 3.	tmpzr1t_l9r_go_relaxed.owl	toll-like receptor 3 signalling pathway|TLR3 signaling pathway													biological_process											owl:Class	
GO:0102433	biolink:NamedThing	phenylalanine 4-hydroxylase (N10-formyl-tetrahydrofolate dependent) activity	Catalysis of the reaction: L-phenylalanine  + O2 + an N10-formyl-tetrahydrofolate <=> L-tyrosine  + a 10-formyltetrahydrofolate-4a-carbinolamine.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-13907									molecular_function											owl:Class	
GO:0016714	biolink:NamedThing	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen	Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from reduced pteridine and one other donor, and one atom of oxygen is incorporated into one donor.	tmpzr1t_l9r_go_relaxed.owl					EC:1.14.16.-									molecular_function											owl:Class	
GO:0120157	biolink:NamedThing	PAR polarity complex	A protein kinase complex that is required for the establishment of a cell polarity axis during the cell division cycle. Binds directly to activated CDC42 GTPase and is required for orchestrating a cellular gradient of CDC42. In S. cerevisiae components are: BEM1, CDC24 and CLA4; from worms to vertebrates it contains a PAR6 protein, PAR3 protein and an atypical PKC.	tmpzr1t_l9r_go_relaxed.owl	Cdc42p GEF-PAK complex|BEM1-CDC24-CLA4 complex|apical polarity complex|PAR3-PAR6-atypical PKC|PAR3/PAR6/aPKC|PAR6-PAR3-aPKC complex					"This tripartite complex named PAR6/PAR3/aPKC is conserved from worms to vertebrates" (PMID:18005931). In yeast, the components are BEM1, CDC24, and CLA4.		krc	2018-05-11T15:41:30Z					cellular_component											owl:Class	
GO:0016328	biolink:NamedThing	lateral plasma membrane	The portion of the plasma membrane at the lateral side of the cell. In epithelial cells, lateral plasma membranes are on the sides of cells which lie at the interface of adjacent cells.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0018013	biolink:NamedThing	N-terminal peptidyl-glycine methylation	The methylation of the N-terminal glycine of proteins to form the derivative N-methylglycine.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0063									biological_process											owl:Class	
GO:0140442	biolink:NamedThing	peroxide sensor activity	Binding to hydrogen peroxide (H2O2) and eliciting a change in the protein's activity in response to the intracellular level of that small molecule.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/19126						pg	2020-03-24T09:09:43Z					molecular_function											owl:Class	
GO:0002556	biolink:NamedThing	serotonin secretion by basophil	The regulated release of serotonin by a basophil or group of basophils.	tmpzr1t_l9r_go_relaxed.owl	serotonin release by basophil													biological_process											owl:Class	
GO:0051403	biolink:NamedThing	stress-activated MAPK cascade	A series of molecular signals in which a stress-activated MAP kinase cascade relays one or more of the signals; MAP kinase cascades involve at least three protein kinase activities and culminate in the phosphorylation and activation of a MAP kinase.	tmpzr1t_l9r_go_relaxed.owl	p38 cascade|p38 MAPK signalling|stress-activated MAPK signaling pathway|stress-activated MAPKKK cascade|stress-activated MAPKKK signaling pathway|MAPK14 cascade|MAPK11 cascade|stress-activated MAPKKK signalling pathway|stress-activated MAPK signalling pathway|p38 MAPK signaling|MAPK12 cascade|SAPK cascade|MAPK13 cascade													biological_process											owl:Class	
GO:0060501	biolink:NamedThing	positive regulation of epithelial cell proliferation involved in lung morphogenesis	Any process that increases the rate or frequency of epithelial cell proliferation that results in the lung attaining its shape.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0071548	biolink:NamedThing	response to dexamethasone	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dexamethasone stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to dexamethasone stimulus							mah	2010-01-13T01:24:40Z					biological_process											owl:Class	
GO:0070536	biolink:NamedThing	protein K63-linked deubiquitination	A protein deubiquitination process in which a K63-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 63 of the ubiquitin monomers, is removed from a protein.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1901596	biolink:NamedThing	response to reversine	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reversine stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2012-11-07T17:17:01Z					biological_process											owl:Class	
GO:0009802	biolink:NamedThing	cinnamic acid ester biosynthetic process	The chemical reactions and pathways resulting in the formation of ester derivatives of cinnamic acid, phenylpropenoic acid.	tmpzr1t_l9r_go_relaxed.owl	cinnamylic acid ester biosynthesis|cinnamylic acid ester biosynthetic process|phenylacrylic acid ester biosynthesis|cinnamic acid ester synthesis|cinnamic acid ester formation|phenylacrylic acid ester biosynthetic process|cinnamic acid ester biosynthesis|cinnamic acid ester anabolism													biological_process											owl:Class	
GO:0010588	biolink:NamedThing	cotyledon vascular tissue pattern formation	Vascular tissue pattern formation as it occurs in the cotyledon of vascular plants.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0099062	biolink:NamedThing	integral component of postsynaptic early endosome membrane	The component of the postsynaptic early endosome membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0010623	biolink:NamedThing	programmed cell death involved in cell development	The activation of endogenous cellular processes that result in the death of a cell as part of its development.	tmpzr1t_l9r_go_relaxed.owl	developmental programmed cell death|programmed cell death involved in development					This process is part of the natural developmental program of some cell types, but it does not always happen as part of the development or shaping of a gross anatomical structure.								biological_process											owl:Class	
GO:0005921	biolink:NamedThing	gap junction	A cell-cell junction composed of pannexins or innexins and connexins, two different families of channel-forming proteins.	tmpzr1t_l9r_go_relaxed.owl	communicating junction|zonula communicans|intercellular gap junction channel|electrotonic synapse|electrical synapse|gap junction plaque|macula communicans|gap junction macula				Wikipedia:Gap_junction|NIF_Subcellular:sao118541872									cellular_component											owl:Class	
GO:0098930	biolink:NamedThing	axonal transport	The directed movement of organelles or molecules along microtubules in axons.	tmpzr1t_l9r_go_relaxed.owl	axoplasmic transport|axon cargo transport				Wikipedia:Axoplasmic_transport									biological_process											owl:Class	
GO:0072658	biolink:NamedThing	maintenance of protein location in membrane	Any process in which a protein is maintained in a specific location in a membrane, and is prevented from moving elsewhere.	tmpzr1t_l9r_go_relaxed.owl								mah	2011-02-14T02:39:41Z					biological_process											owl:Class	
GO:0034128	biolink:NamedThing	negative regulation of MyD88-independent toll-like receptor signaling pathway	Any process that stops, prevents, or reduces the frequency, rate, or extent of MyD88-independent toll-like receptor signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of MyD88-independent toll-like receptor signalling pathway|negative regulation of MyD88-independent TLR signaling pathway													biological_process											owl:Class	
GO:0044676	biolink:NamedThing	formyl-methanofuran dehydrogenase (molybdenum enzyme) complex	A protein complex consisting of three polypeptides which also contains molybdenum, a molybdopterin guanine dinucleotide and iron-sulfur clusters. This protein complex catalyzes the reversible conversion of CO2 and methanofuran to formylmethanofuran during methanogenesis.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-08-09T10:56:51Z					cellular_component											owl:Class	
GO:0070342	biolink:NamedThing	brown fat cell proliferation	The multiplication or reproduction of brown fat cells by cell division, resulting in the expansion of their population. A brown fat cell is a fat cell found the thermogenic form of adipose tissue found in newborns of many species.	tmpzr1t_l9r_go_relaxed.owl	brown adipocyte proliferation|brown adipose cell proliferation													biological_process											owl:Class	
GO:0002257	biolink:NamedThing	negative regulation of kinin cascade	Any process that stops, prevents, or reduces the frequency, rate, or extent of the kinin cascade.	tmpzr1t_l9r_go_relaxed.owl	down regulation of kinin cascade|inhibition of kinin cascade|down-regulation of kinin cascade|downregulation of kinin cascade													biological_process											owl:Class	
GO:0106155	biolink:NamedThing	peptidyl-lysine 3-dioxygenase activity	Catalysis of the reaction: protein L-lysine + 2-oxoglutarate + O2 = protein 3-hydroxy-L-lysine + succinate + CO2.	tmpzr1t_l9r_go_relaxed.owl					EC:1.14.11.63|RHEA:57152			hjd	2018-11-15T20:09:45Z					molecular_function											owl:Class	
GO:1902266	biolink:NamedThing	cellular abscisic acid homeostasis	Any biological process involved in the maintenance of an internal steady state of abscisic acid at the level of the cell.	tmpzr1t_l9r_go_relaxed.owl	cellular ABA homeostasis|cellular 2-cis-abscisate homeostasis							tb	2013-06-27T21:05:36Z					biological_process											owl:Class	
GO:1902265	biolink:NamedThing	abscisic acid homeostasis	Any process involved in the maintenance of an internal steady state of abscisic acid within an organism or cell.	tmpzr1t_l9r_go_relaxed.owl	2-cis-abscisate homeostasis|ABA homeostasis							tb	2013-06-27T21:05:30Z					biological_process											owl:Class	
GO:0032065	biolink:NamedThing	maintenance of protein location in cell cortex	A process in which a protein or protein complex is maintained in a specific location in the cell cortex.	tmpzr1t_l9r_go_relaxed.owl	cortical protein anchoring													biological_process											owl:Class	
GO:0002028	biolink:NamedThing	regulation of sodium ion transport	Any process that modulates the frequency, rate or extent of the directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	regulation of sodium transport|regulation of Na+ transport													biological_process											owl:Class	
GO:0106021	biolink:NamedThing	negative regulation of vesicle docking	Any process that stops, prevents, or reduces the frequency, rate or extent of vesicle docking.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of vesicle to membrane docking							hjd	2017-05-16T14:05:29Z					biological_process											owl:Class	
GO:0033459	biolink:NamedThing	GAA codon-amino acid adaptor activity	A triplet codon-amino acid adaptor activity that recognizes a GAA codon.	tmpzr1t_l9r_go_relaxed.owl	glutamic acid tRNA					Note that in the standard genetic code, GAA codes for glutamic acid.								molecular_function											owl:Class	
GO:0097273	biolink:NamedThing	creatinine homeostasis	Any biological process involved in the maintenance of an internal steady state of creatinine.	tmpzr1t_l9r_go_relaxed.owl								pr	2012-03-22T02:52:50Z					biological_process											owl:Class	
GO:0033451	biolink:NamedThing	GUA codon-amino acid adaptor activity	A triplet codon-amino acid adaptor activity that recognizes a GUA codon.	tmpzr1t_l9r_go_relaxed.owl	valine tRNA|GTA codon-amino acid adaptor activity					Note that in the standard genetic code, GTA codes for valine.								molecular_function											owl:Class	
GO:0070385	biolink:NamedThing	egasyn-beta-glucuronidase complex	A protein complex that contains beta-glucuronidase and the carboxyl esterase egasyn; formation of the complex causes beta-glucuronidase to be retained in the endoplasmic reticulum.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0072258	biolink:NamedThing	metanephric interstitial fibroblast differentiation	The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the interstitial fibroblasts of the metanephros as it progresses from its formation to the mature state.	tmpzr1t_l9r_go_relaxed.owl	metanephros interstitial cell differentiation							mah	2010-03-19T04:17:32Z					biological_process											owl:Class	
GO:0010202	biolink:NamedThing	response to low fluence red light stimulus	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a low fluence red light stimulus. Red light is electromagnetic radiation of wavelength of 580-700nm. Low fluence red light is defined in this case as short pulses of red light followed by darkness, providing a light level of 0.001-0.1 mmol/m2/sec.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0035830	biolink:NamedThing	palmatine metabolic process	The chemical reactions and pathways involving palmatine, a berberine alkaloid found in many plants.	tmpzr1t_l9r_go_relaxed.owl	palmatine metabolism							bf	2011-05-04T03:04:38Z					biological_process											owl:Class	
GO:0072345	biolink:NamedThing	NAADP-sensitive calcium-release channel activity	Enables the transmembrane transfer of a calcium ion by a channel that opens when nicotinic acid adenine dinucleotide phosphate (NAADP) has been bound by the channel complex or one of its constituent parts.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-2685505			mah	2010-11-10T01:03:35Z					molecular_function											owl:Class	
GO:1903415	biolink:NamedThing	flavonoid transport from endoplasmic reticulum to plant-type vacuole	The directed movement of flavonoid from endoplasmic reticulum to plant-type vacuole.	tmpzr1t_l9r_go_relaxed.owl	flavonoid accumulation in vacuole							tb	2014-09-05T00:35:34Z					biological_process											owl:Class	
GO:0045209	biolink:NamedThing	MAPK phosphatase export from nucleus, leptomycin B sensitive	Leptomycin B-sensitive movement of a MAPK phosphatase from the nucleus to the cytoplasm.	tmpzr1t_l9r_go_relaxed.owl	MAPK phosphatase-nucleus export, leptomycin B sensitive|leptomycin B-sensitive MAPK phosphatase transport from nucleus to cytoplasm|MAPK phosphatase export out of nucleus, leptomycin B sensitive|leptomycin B-sensitive MAPK phosphatase-nucleus export|MAPK phosphatase transport from nucleus to cytoplasm, leptomycin B sensitive|leptomycin B-sensitive MAPK phosphatase export out of nucleus|MAPK phosphatase export from cell nucleus, leptomycin B sensitive													biological_process											owl:Class	
GO:0045208	biolink:NamedThing	MAPK phosphatase export from nucleus	The directed movement of a MAPK phosphatase from the nucleus to the cytoplasm.	tmpzr1t_l9r_go_relaxed.owl	MAPK phosphatase-nucleus export|MAPK phosphatase export from cell nucleus|MAPK phosphatase export out of nucleus|MAPK phosphatase transport from nucleus to cytoplasm													biological_process											owl:Class	
GO:0018936	biolink:NamedThing	anaerobic nitrilotriacetate metabolic process	The chemical reactions and pathways involving nitrilotriacetate, the aminotricarboxylic acid N(CH2COO-)3, that occur in the absence of oxygen.	tmpzr1t_l9r_go_relaxed.owl	anaerobic nitrilotriacetate metabolism													biological_process											owl:Class	
GO:0060309	biolink:NamedThing	elastin catabolic process	The chemical reactions and pathways resulting in the breakdown of elastin. Elastin is a glycoprotein which is randomly coiled and crosslinked to form elastic fibers that are found in connective tissue.	tmpzr1t_l9r_go_relaxed.owl	elastin breakdown|elastin catabolism|elastin degradation													biological_process											owl:Class	
GO:0006990	biolink:NamedThing	positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response	The activation of genes whose promoters contain a specific sequence elements such as the unfolded protein response element (UPRE; consensus CAGCGTG) or the ER stress-response element (ERSE; CCAAN(N)9CCACG), as a result of signaling via the unfolded protein response.	tmpzr1t_l9r_go_relaxed.owl	unfolded protein response, up-regulation of target gene transcription|unfolded protein response, positive regulation of target gene transcription|positive regulation of transcription of target genes involved in unfolded protein response|unfolded protein response, stimulation of target gene transcription|unfolded protein response, upregulation of target gene transcription|unfolded protein response, target gene transcriptional activation|unfolded protein response, up regulation of target gene transcription|unfolded protein response, activation of target gene transcription													biological_process											owl:Class	
GO:0035233	biolink:NamedThing	germ cell repulsion	The directed movement of a germ cell from their site of production to the gonad, through the repulsion of cells away from a tissue.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0050919	biolink:NamedThing	negative chemotaxis	The directed movement of a motile cell or organism towards a lower concentration of a chemical.	tmpzr1t_l9r_go_relaxed.owl	chemorepulsion|chemoaversion													biological_process											owl:Class	
GO:0015820	biolink:NamedThing	leucine transport	The directed movement of leucine, 2-amino-4-methylpentanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	L-leucine transport													biological_process											owl:Class	
GO:0106032	biolink:NamedThing	snRNA pseudouridine synthase activity	Catalysis of the reaction: an snRNA uridine = an snRNA pseudouridine. Conversion of uridine in an snRNA molecule to pseudouridine by rotation of the C1'-N-1 glycosidic bond of uridine in RNA to a C1'-C5.	tmpzr1t_l9r_go_relaxed.owl								hjd	2017-06-28T17:44:20Z					molecular_function											owl:Class	
GO:0009982	biolink:NamedThing	pseudouridine synthase activity	Catalysis of the reaction: RNA uridine = RNA pseudouridine. Conversion of uridine in an RNA molecule to pseudouridine by rotation of the C1'-N-1 glycosidic bond of uridine in RNA to a C1'-C5.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-6786583|Reactome:R-HSA-6790905|Reactome:R-HSA-8870289|Reactome:R-HSA-6787566|Reactome:R-HSA-6782381	Note that this term should not be confused with 'pseudouridylate synthase activity ; GO:0004730', which refers to the formation of free pseudouridine from uracil and ribose-5-phosphate.						GO:0016439		molecular_function											owl:Class	
GO:0043310	biolink:NamedThing	negative regulation of eosinophil degranulation	Any process that stops, prevents, or reduces the rate of eosinophil degranulation.	tmpzr1t_l9r_go_relaxed.owl	downregulation of eosinophil degranulation|down-regulation of eosinophil degranulation|negative regulation of eosinophil granule exocytosis|inhibition of eosinophil degranulation|down regulation of eosinophil degranulation													biological_process											owl:Class	
GO:0062142	biolink:NamedThing	L-beta-ethynylserine biosynthetic process	The chemical reactions and pathways resulting in the formation of L-beta-ethynylserine. L-beta-ethynylserine is an antibiotic produced by Streptomyces bacteria.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/17763						dph	2019-09-02T16:39:59Z					biological_process											owl:Class	
GO:0120237	biolink:NamedThing	terminal acetylenic compound biosynthetic process	The chemical reactions and pathways resulting in the formation of a terminal acetylenic compound, a compound which contains a terminal alkyne moiety in which a carbon of the carbon-carbon triple bond (aka C#C) moiety is attached to a hydrogen atom.	tmpzr1t_l9r_go_relaxed.owl	terminal alkyne substituted compound synthesis|terminal alkyne substituted compound biosynthetic process|terminal alkyne substituted compound biosynthesis|terminal alkyne substituted compound anabolic process|terminal alkyne substituted compound anabolism	https://github.com/geneontology/go-ontology/issues/17763						krc	2020-07-17T20:19:10Z					biological_process											owl:Class	
GO:0060211	biolink:NamedThing	regulation of nuclear-transcribed mRNA poly(A) tail shortening	Any process that modulates the frequency, rate or extent of poly(A) tail shortening of a nuclear-transcribed mRNA. Poly(A) tail shortening is the decrease in length of the poly(A) tail of an mRNA from full length to an oligo(A) length.	tmpzr1t_l9r_go_relaxed.owl	regulation of nuclear mRNA poly(A) tail shortening|regulation of mRNA deadenylation|regulation of 3' to 5' mRNA deadenylation													biological_process											owl:Class	
GO:0045693	biolink:NamedThing	positive regulation of embryo sac central cell differentiation	Any process that activates or increases the frequency, rate or extent of embryo sac central cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of female gametophyte central cell differentiation|positive regulation of female gametophyte central cell differentiation|upregulation of female gametophyte central cell differentiation|stimulation of female gametophyte central cell differentiation|up regulation of female gametophyte central cell differentiation|activation of female gametophyte central cell differentiation													biological_process											owl:Class	
GO:0019143	biolink:NamedThing	3-deoxy-manno-octulosonate-8-phosphatase activity	Catalysis of the reaction: 8-phospho-3-deoxy-D-manno-oct-2-ulosonate + H(2)O = 3-deoxy-D-manno-octulosonate + phosphate.	tmpzr1t_l9r_go_relaxed.owl	3-deoxy-D-manno-octulosonate-8-phosphate 8-phosphohydrolase activity				MetaCyc:KDO-8PPHOSPHAT-RXN|RHEA:11500|EC:3.1.3.45|KEGG_REACTION:R03350									molecular_function											owl:Class	
GO:0007580	biolink:NamedThing	extrachromosomal circular DNA accumulation involved in cell aging	Increase in abundance, as cells age, of circular DNA molecules that originate in the chromosome but are excised and circularized, often by intramolecular homologous recombination between direct tandem repeats, and replicated independently of chromosomal replication.	tmpzr1t_l9r_go_relaxed.owl	extrachromosomal circular DNA accumulation during cell ageing|extrachromosomal circular DNA accumulation during cell aging					Note that the term string was changed to be consistent with placement of this term in cell aging hierarchy.								biological_process											owl:Class	
GO:0001301	biolink:NamedThing	progressive alteration of chromatin involved in cell aging	Any chromatin organization process that occurs during the lifespan of the cell that results in changes in chromatin structure. Such changes may lead to gene dysregulation and ultimately to a loss in cell homeostasis, bringing about an aging phenotype.	tmpzr1t_l9r_go_relaxed.owl	progressive alteration of chromatin during cell aging|age-dependent accumulation of genetic damage|progressive alteration of chromatin during cell ageing													biological_process											owl:Class	
GO:1904159	biolink:NamedThing	megasporocyte differentiation	The process in which a relatively unspecialized cell acquires the specialized features of a megasporocyte.	tmpzr1t_l9r_go_relaxed.owl	megaspore mother cell differentiation					The process aimed at the progression of a megasporocyte cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. A megasporocyte is a diploid (2n) cell that undergoes meiosis and forms four haploid (1n) megaspores; also called megaspore mother cell.		lr	2015-04-17T20:25:14Z					biological_process											owl:Class	
GO:0048533	biolink:NamedThing	sporocyte differentiation	The process in which a relatively unspecialized floral cell acquires the specialized features of a sporocyte. Sporocytes are the haploid spores of angiosperms. Once formed, they undergo meiotic divisions to form microspores and megaspores.	tmpzr1t_l9r_go_relaxed.owl	sporocyte development|sporocyte morphogenesis													biological_process											owl:Class	
GO:0071152	biolink:NamedThing	G-protein alpha(q)-synembrin complex	A protein complex formed by the association of the guanine nucleotide exchange factor synembrin with the alpha(q) subunit of a heterotrimeric G protein.	tmpzr1t_l9r_go_relaxed.owl	Ric-8A G(q) alpha subunit complex							mah	2009-11-16T04:48:05Z					cellular_component											owl:Class	
GO:0015391	biolink:NamedThing	nucleobase:cation symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: nucleobase(out) + cation(out) = nucleobase(in) + cation(in).	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0015294	biolink:NamedThing	solute:cation symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: solute(out) + cation(out) = solute(in) + cation(in).	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1901174	biolink:NamedThing	phytoene biosynthetic process	The chemical reactions and pathways resulting in the formation of phytoene.	tmpzr1t_l9r_go_relaxed.owl	phytoene formation|phytoene anabolism|phytoene synthesis|phytoene biosynthesis							yaf	2012-07-19T09:48:15Z					biological_process											owl:Class	
GO:0045442	biolink:NamedThing	deacetoxycephalosporin-C hydroxylase activity	Catalysis of the reaction: 2-oxoglutarate + deacetoxycephalosporin C + O(2) = CO(2) + deacetylcephalosporin C + succinate.	tmpzr1t_l9r_go_relaxed.owl	deacetoxycephalosporin-C,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating) activity|DACS|beta-lactam hydroxylase activity|3'-methylcephem hydroxylase activity|deacetylcephalosporin C synthase activity|deacetoxycephalosporin C hydroxylase activity|DAOC hydroxylase activity				EC:1.14.11.26|KEGG_REACTION:R05229|MetaCyc:1.14.11.26-RXN|RHEA:16805									molecular_function											owl:Class	
GO:0008843	biolink:NamedThing	endochitinase activity	Catalysis of the hydrolysis of nonterminal (1->4)-beta linkages of N-acetyl-D-glucosamine (GlcNAc) polymers of chitin and chitodextrins. Typically, endochitinases cleave randomly within the chitin chain.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1902050	biolink:NamedThing	neosartoricin biosynthetic process	The chemical reactions and pathways resulting in the formation of neosartoricin.	tmpzr1t_l9r_go_relaxed.owl	neosartoricin formation|neosartoricin anabolism|neosartoricin biosynthesis|neosartoricin synthesis							di	2013-04-08T20:31:11Z					biological_process											owl:Class	
GO:0006615	biolink:NamedThing	SRP-dependent cotranslational protein targeting to membrane, docking	The process in which an SRP-bound ribosome forms a complex with the SRP receptor in the ER membrane, allowing the ribosome to bind to the membrane, during cotranslational membrane targeting.	tmpzr1t_l9r_go_relaxed.owl	protein docking during SRP-dependent cotranslational protein targeting to membrane|SRP-dependent cotranslational protein-membrane targeting, docking|SRP-dependent cotranslational membrane targeting, docking													biological_process											owl:Class	
GO:0022615	biolink:NamedThing	protein to membrane docking	The initial attachment of a protein to a target membrane, mediated by a proteins protruding from the target membrane. Docking requires only that the proteins come close enough to interact and adhere.	tmpzr1t_l9r_go_relaxed.owl	protein-membrane docking													biological_process											owl:Class	
GO:1990261	biolink:NamedThing	pre-mRNA catabolic process	The chemical reactions and pathways resulting in the breakdown of the unspliced pre-mRNA (pre-messenger RNA).	tmpzr1t_l9r_go_relaxed.owl	unspliced RNA decay|pre-mRNA decay							rb	2014-01-07T23:06:44Z					biological_process											owl:Class	
GO:0006972	biolink:NamedThing	hyperosmotic response	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a hyperosmotic environment, i.e. an environment with a higher concentration of solutes than the organism or cell.	tmpzr1t_l9r_go_relaxed.owl	response to hypertonicity|HOG response|hypertonic response													biological_process											owl:Class	
GO:2000017	biolink:NamedThing	positive regulation of determination of dorsal identity	Any process that activates or increases the frequency, rate or extent of determination of dorsal identity.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of determination of adaxial identity							jl	2010-07-15T03:27:59Z					biological_process											owl:Class	
GO:0019199	biolink:NamedThing	transmembrane receptor protein kinase activity	Combining with a signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: a protein + ATP = a phosphoprotein + ADP.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-8983063|Reactome:R-HSA-8983059									molecular_function											owl:Class	
GO:0035445	biolink:NamedThing	borate transmembrane transport	The process in which borate is transported across a membrane. Borate is the anion (BO3)3-; boron is a group 13 element, with properties which are borderline between metals and non-metals.	tmpzr1t_l9r_go_relaxed.owl	borate membrane transport|boron transmembrane transport					Note that this term is not intended for use in annotating lateral movement within membranes.		bf	2010-04-13T09:24:23Z					biological_process											owl:Class	
GO:0090116	biolink:NamedThing	C-5 methylation of cytosine	The covalent transfer of a methyl group to C-5 of cytosine in a DNA molecule.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-12-07T11:58:47Z					biological_process											owl:Class	
GO:0032776	biolink:NamedThing	DNA methylation on cytosine	The covalent transfer of a methyl group to C-5 or N-4 of cytosine in a DNA molecule.	tmpzr1t_l9r_go_relaxed.owl	cytosine methylation													biological_process											owl:Class	
GO:0061941	biolink:NamedThing	positive regulation of c-di-GMP signaling	Any process that increases the rate, frequency or extent of c-di-GMP signaling.	tmpzr1t_l9r_go_relaxed.owl								dph	2017-09-14T19:11:15Z					biological_process											owl:Class	
GO:0050330	biolink:NamedThing	theanine hydrolase activity	Catalysis of the reaction: N(5)-ethyl-L-glutamine + H(2)O = L-glutamate + ethylamine.	tmpzr1t_l9r_go_relaxed.owl	N5-ethyl-L-glutamine amidohydrolase activity|L-theanine amidohydrolase activity|5-N-ethyl-L-glutamine amidohydrolase activity				KEGG_REACTION:R02930|EC:3.5.1.65|RHEA:18013|MetaCyc:THEANINE-HYDROLASE-RXN									molecular_function											owl:Class	
GO:0033969	biolink:NamedThing	gamma-glutamyl-gamma-aminobutyrate hydrolase activity	Catalysis of the reaction: 4-(L-gamma-glutamylamino)butanoate + H(2)O = 4-aminobutanoate + L-glutamate.	tmpzr1t_l9r_go_relaxed.owl	gamma-glutamyl-GABA hydrolase activity|YcjL|PuuD|4-(glutamylamino)butanoate amidohydrolase activity				KEGG_REACTION:R07419|EC:3.5.1.94|MetaCyc:RXN0-3942|RHEA:19737									molecular_function											owl:Class	
GO:0034227	biolink:NamedThing	tRNA thio-modification	The addition a sulfur atom to a nucleotide in a tRNA molecule.	tmpzr1t_l9r_go_relaxed.owl	tRNA thiolation|tRNA sulfurtransferase activity													biological_process											owl:Class	
GO:0010444	biolink:NamedThing	guard mother cell differentiation	The process in which a meristemoid acquires the specialized features of a guard mother cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0071016	biolink:NamedThing	U12-type precatalytic spliceosome	A spliceosomal complex that is formed by the recruitment of the preassembled U4atac/U6atac.U5 tri-snRNP to the U12-type prespliceosome. Although all 5 snRNPs are present, the precatalytic spliceosome is catalytically inactive. The precatalytic spliceosome includes many proteins in addition to those found in the U11, U12 and U4atac/U6atac.U5 snRNPs.	tmpzr1t_l9r_go_relaxed.owl	mammalian U12-type spliceosomal complex B|minor precatalytic spliceosome|AT-AC precatalytic spliceosome|yeast U12-type spliceosomal complex A2-1|mammalian U12-type spliceosomal complex B1							mah	2009-07-30T12:00:35Z					cellular_component											owl:Class	
GO:0005689	biolink:NamedThing	U12-type spliceosomal complex	Any spliceosomal complex that forms during the splicing of a messenger RNA primary transcript to excise an intron; the series of U12-type spliceosomal complexes is involved in the splicing of the majority of introns that contain atypical AT-AC terminal dinucleotides, as well as other non-canonical introns. The entire splice site signal, not just the terminal dinucleotides, is involved in determining which spliceosome utilizes the site.	tmpzr1t_l9r_go_relaxed.owl	AT-AC spliceosomal complex|minor spliceosomal complex|minor (U12-type) spliceosomal complex				Wikipedia:Minor_spliceosome									cellular_component											owl:Class	
GO:0075119	biolink:NamedThing	induction by symbiont of host G protein-coupled receptor signal transduction	Any process in which the symbiont activates, maintains or increases the frequency, rate or extent of the host G protein-coupled receptor signal transduction. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	positive regulation by symbiont of host G protein-coupled receptor signal transduction|positive regulation by symbiont of host signal transduction mediated by G-protein alpha subunit|positive regulation by symbiont of host signal transduction mediated by G-protein beta subunit|positive regulation by symbiont of host signal transduction mediated by G-protein gamma subunit|positive regulation by symbiont of host G-protein coupled receptor protein signal transduction					Note that this term is used to annotate gene products of the symbiont. To annotate host gene products, consider the biological process term "positive regulation by symbiont of host G protein-coupled receptor signal transduction ; GO:0075088".						GO:0075125|GO:0075128|GO:0075122		biological_process											owl:Class	
GO:0075113	biolink:NamedThing	induction by symbiont of host transmembrane receptor-mediated signal transduction	Any process in which the symbiont activates, maintains or increases the frequency, rate or extent of transmembrane receptor-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	positive regulation by symbiont of host transmembrane receptor-mediated signal transduction					Note that this term is used to annotate gene products of the symbiont. To annotate host gene products, consider the biological process term "positive regulation by host of symbiont transmembrane receptor-mediated signal transduction ; GO:0075082".								biological_process											owl:Class	
GO:1905408	biolink:NamedThing	negative regulation of creatine transmembrane transporter activity	Any process that stops, prevents or reduces the frequency, rate or extent of creatine transmembrane transporter activity.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of creatine transmembrane transporter activity|inhibition of creatine transmembrane transporter activity|down regulation of creatine transmembrane transporter activity|downregulation of creatine transmembrane transporter activity							bc	2016-08-25T15:08:56Z					biological_process											owl:Class	
GO:0015200	biolink:NamedThing	methylammonium transmembrane transporter activity	Enables directed movement of methylammonium, CH3NH2, from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0071038	biolink:NamedThing	nuclear polyadenylation-dependent tRNA catabolic process	The chemical reactions and pathways occurring in the nucleus and resulting in the breakdown of an aberrant or incorrectly modified transfer RNA (tRNA) molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target tRNA.	tmpzr1t_l9r_go_relaxed.owl	nuclear poly(A)-dependent tRNA catabolic process							krc	2009-07-29T01:08:14Z					biological_process											owl:Class	
GO:0106354	biolink:NamedThing	tRNA surveillance	The set of processes involved in identifying and degrading defective or aberrant tRNAs.	tmpzr1t_l9r_go_relaxed.owl								hjd	2021-01-27T16:29:46Z					biological_process											owl:Class	
GO:0051522	biolink:NamedThing	activation of monopolar cell growth	Any process that initiates the inactive process of monopolar cell growth, polarized growth from one end of a cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0051515	biolink:NamedThing	positive regulation of monopolar cell growth	Any process that activates or increases the frequency, rate or extent of monopolar cell growth, polarized growth from one end of a cell.	tmpzr1t_l9r_go_relaxed.owl	up regulation of monopolar cell growth|stimulation of monopolar cell growth|up-regulation of monopolar cell growth|upregulation of monopolar cell growth													biological_process											owl:Class	
GO:0071090	biolink:NamedThing	alphaIIb-beta3 integrin-fibronectin-tissue transglutaminase complex	A protein complex that consists of an alphaIIb-beta3 integrin complex bound to fibronectin and tissue transglutaminase.	tmpzr1t_l9r_go_relaxed.owl	ITGA2b-ITGB3-FN1-TGM2 complex							mah	2009-11-06T04:46:24Z					cellular_component											owl:Class	
GO:0045482	biolink:NamedThing	trichodiene synthase activity	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = diphosphate + trichodiene.	tmpzr1t_l9r_go_relaxed.owl	trans,trans-farnesyl-diphosphate diphosphate-lyase (cyclizing, trichodiene-forming)|sesquiterpene cyclase activity|trans,trans-farnesyl-diphosphate sesquiterpenoid-lyase activity|trichodiene synthetase activity				RHEA:12052|KEGG_REACTION:R02306|MetaCyc:TRICHODIENE-SYNTHASE-RXN|EC:4.2.3.6									molecular_function											owl:Class	
GO:2000557	biolink:NamedThing	regulation of immunoglobulin production in mucosal tissue	Any process that modulates the frequency, rate or extent of immunoglobulin production in mucosal tissue.	tmpzr1t_l9r_go_relaxed.owl	regulation of antibody production in mucosal tissue							ebc	2011-04-03T07:52:09Z					biological_process											owl:Class	
GO:1990066	biolink:NamedThing	energy quenching	The process by which excess light energy absorbed by chlorophyll and not used to drive photosynthesis is emitted by nonphotochemical quenching or chlorophyll fluorescence.	tmpzr1t_l9r_go_relaxed.owl								tb	2013-03-27T21:02:00Z					biological_process											owl:Class	
GO:0072765	biolink:NamedThing	centromere localization	A cellular localization process in which a centromere/kinetochore is transported to, or maintained in, a specific location.	tmpzr1t_l9r_go_relaxed.owl	kinetochore localization|establishment and maintenance of kinetochore localization|kinetochore localisation							mah	2012-11-21T13:30:53Z					biological_process											owl:Class	
GO:0090446	biolink:NamedThing	negative regulation of nematode larval development, heterochronic	Any process that modulates the consistent predetermined time point at which a nematode larva progresses from an initial condition to a later condition and decreases the rate at which this time point is reached.	tmpzr1t_l9r_go_relaxed.owl								tb	2012-08-24T13:24:43Z					biological_process											owl:Class	
GO:0045961	biolink:NamedThing	negative regulation of development, heterochronic	Any process that modulates the consistent predetermined time point at which an integrated living unit or organism progresses from an initial condition to a later condition and decreases the rate at which this time point is reached.	tmpzr1t_l9r_go_relaxed.owl	downregulation of development, heterochronic|down regulation of development, heterochronic|down-regulation of development, heterochronic|inhibition of development, heterochronic													biological_process											owl:Class	
GO:1900575	biolink:NamedThing	emodin biosynthetic process	The chemical reactions and pathways resulting in the formation of emodin.	tmpzr1t_l9r_go_relaxed.owl	emodin synthesis|emodin formation|emodin anabolism|emodin biosynthesis							di	2012-05-15T06:42:14Z					biological_process											owl:Class	
GO:1990711	biolink:NamedThing	beta-catenin-ICAT complex	Transcription factor complex that inhibits binding of Tcf to beta-catenin while preserving interaction of catenin with cadherin thus inhibiting transcription mediated by beta-catenin-Tcf complex.	tmpzr1t_l9r_go_relaxed.owl	CTNNB1-CTNNBIP1 complex					An example of this is Catenin beta-1 in human (UniProt symbol P35222) in PMID:12408824 (inferred from physical interaction).		bhm	2015-03-25T21:08:11Z					cellular_component											owl:Class	
GO:0015734	biolink:NamedThing	taurine transport	The directed movement of taurine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0046130	biolink:NamedThing	purine ribonucleoside catabolic process	The chemical reactions and pathways resulting in the breakdown of any purine ribonucleoside, a nucleoside in which purine base is linked to a ribose (beta-D-ribofuranose) molecule.	tmpzr1t_l9r_go_relaxed.owl	purine ribonucleoside degradation|purine ribonucleoside breakdown|purine ribonucleoside catabolism													biological_process											owl:Class	
GO:0042454	biolink:NamedThing	ribonucleoside catabolic process	The chemical reactions and pathways resulting in the breakdown of any ribonucleoside, a nucleoside in which purine or pyrimidine base is linked to a ribose (beta-D-ribofuranose) molecule.	tmpzr1t_l9r_go_relaxed.owl	ribonucleoside degradation|ribonucleoside breakdown|ribonucleoside catabolism													biological_process											owl:Class	
GO:2000203	biolink:NamedThing	regulation of ribosomal large subunit export from nucleus	Any process that modulates the frequency, rate or extent of ribosomal large subunit export from nucleus.	tmpzr1t_l9r_go_relaxed.owl	regulation of ribosomal large subunit transport from nucleus to cytoplasm|regulation of 60S ribosomal subunit export from nucleus|regulation of 50S ribosomal subunit export from nucleus|regulation of ribosomal large subunit export out of nucleus|regulation of ribosomal large subunit export from cell nucleus|regulation of ribosomal large subunit-nucleus export							mah	2010-10-26T10:52:36Z					biological_process											owl:Class	
GO:0002405	biolink:NamedThing	antigen sampling by dendritic cells in mucosal-associated lymphoid tissue	The process of antigen sampling carried out by dendritic cells in the mucosal-associated lymphoid tissue.	tmpzr1t_l9r_go_relaxed.owl	antigen sampling by dendritic cells in MALT													biological_process											owl:Class	
GO:0031155	biolink:NamedThing	regulation of reproductive fruiting body development	Any process that modulates the frequency, rate or extent of reproductive fruiting body development.	tmpzr1t_l9r_go_relaxed.owl	regulation of fruiting body formation													biological_process											owl:Class	
GO:0061243	biolink:NamedThing	mesonephric renal vesicle morphogenesis	The process in which the anatomical structures of the mesonephric renal vesicle are generated and organized. The renal vesicle is the primordial structure of the mesonephric nephron epithelium, and is formed by the condensation of mesenchymal cells.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-08-19T03:20:21Z					biological_process											owl:Class	
GO:0072077	biolink:NamedThing	renal vesicle morphogenesis	The process in which the anatomical structures of the renal vesicle are generated and organized. The renal vesicle is the primordial structure of the nephron epithelium, and is formed by the condensation of mesenchymal cells.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-02-01T02:21:06Z					biological_process											owl:Class	
GO:0001743	biolink:NamedThing	lens placode formation	The initial developmental process that will lead to the formation of an eye.	tmpzr1t_l9r_go_relaxed.owl	optic placode formation													biological_process											owl:Class	
GO:1990193	biolink:NamedThing	BtuCD complex	Protein complex involved in cobalamin (vitamin B12) transport through the plasma membrane. In E. coli, the complex is a tetramer and consists of the cytoplasmic ATPase BtuD homodimer together with the transmembrane BtuC homodimer.	tmpzr1t_l9r_go_relaxed.owl	cobalamin transport complex, core subunit|vitamin B12 transport complex, core subunit|BtuC-BtuD complex							bhm	2013-09-12T14:58:56Z					cellular_component											owl:Class	
GO:0008360	biolink:NamedThing	regulation of cell shape	Any process that modulates the surface configuration of a cell.	tmpzr1t_l9r_go_relaxed.owl												GO:0045789|GO:0045788		biological_process											owl:Class	
GO:0002504	biolink:NamedThing	antigen processing and presentation of peptide or polysaccharide antigen via MHC class II	The process in which an antigen-presenting cell expresses antigen (peptide or polysaccharide) on its cell surface in association with an MHC class II protein complex.	tmpzr1t_l9r_go_relaxed.owl	peptide or polysaccharide antigen processing and presentation of via MHC class II													biological_process											owl:Class	
GO:0006122	biolink:NamedThing	mitochondrial electron transport, ubiquinol to cytochrome c	The transfer of electrons from ubiquinol to cytochrome c that occurs during oxidative phosphorylation, mediated by the multisubunit enzyme known as complex III.	tmpzr1t_l9r_go_relaxed.owl	complex III (ubiquinone to cytochrome c)													biological_process											owl:Class	
GO:0060519	biolink:NamedThing	cell adhesion involved in prostatic bud elongation	The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules that contributes to the elongation of the primary prostatic bud.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0002085	biolink:NamedThing	inhibition of neuroepithelial cell differentiation	Any process that prevents the activation of neuroepithelial cell differentiation. Neuroepithelial cell differentiation is the process in which epiblast cells acquire specialized features of neuroepithelial cells.	tmpzr1t_l9r_go_relaxed.owl	repression of premature neural plate formation|negative regulation of neural plate formation													biological_process											owl:Class	
GO:0048505	biolink:NamedThing	regulation of timing of cell differentiation	The process controlling the activation and/or rate at which relatively unspecialized cells acquire specialized features. Any process that modulates the rate, frequency or extent of the XXX at a consistent predetermined time point during its development.	tmpzr1t_l9r_go_relaxed.owl	timing of cell differentiation													biological_process											owl:Class	
GO:0140500	biolink:NamedThing	regulation of reticulophagy	Any process that modulates the frequency, rate or extent of reticulophagy.	tmpzr1t_l9r_go_relaxed.owl	regulation of ER degradation|regulation of autophagy of the ER|regulation of endoplasmic reticulum autophagy|regulation of endoplasmic reticulum degradation|regulation of autophagy of the endoplasmic reticulum|regulation of ER autophagy|regulation of ER-phagy	https://github.com/geneontology/go-ontology/issues/19860						pg	2020-08-10T12:01:22Z					biological_process											owl:Class	
GO:1903536	biolink:NamedThing	positive regulation of lactose biosynthetic process	Any process that activates or increases the frequency, rate or extent of lactose biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	upregulation of lactose biosynthesis|activation of lactose biosynthesis|activation of lactose formation|up regulation of lactose biosynthetic process|upregulation of lactose anabolism|up-regulation of lactose biosynthetic process|upregulation of lactose formation|up-regulation of lactose formation|up-regulation of lactose anabolism|positive regulation of lactose formation|up regulation of lactose formation|up-regulation of lactose synthesis|up regulation of lactose anabolism|positive regulation of lactose synthesis|up-regulation of lactose biosynthesis|up regulation of lactose biosynthesis|activation of lactose anabolism|activation of lactose synthesis|up regulation of lactose synthesis|positive regulation of lactose biosynthesis|upregulation of lactose synthesis|upregulation of lactose biosynthetic process|positive regulation of lactose anabolism|activation of lactose biosynthetic process							mr	2014-10-08T16:26:29Z					biological_process											owl:Class	
GO:0021889	biolink:NamedThing	olfactory bulb interneuron differentiation	The process in which a neuroblast acquires specialized features of an interneuron residing in the olfactory bulb.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0009358	biolink:NamedThing	polyphosphate kinase complex	A protein complex that possesses polyphosphate kinase activity.	tmpzr1t_l9r_go_relaxed.owl						See also the molecular function term 'polyphosphate kinase activity ; GO:0008976'.								cellular_component											owl:Class	
GO:1990108	biolink:NamedThing	protein linear deubiquitination	A protein deubiquitination process in which a linear polymer of ubiquitin, formed by the amino-terminal methionine (M1) of one ubiquitin molecule and by the carboxy-terminal glycine (G76) of the next, is removed from a protein.	tmpzr1t_l9r_go_relaxed.owl								sp	2013-05-29T05:58:49Z					biological_process											owl:Class	
GO:0033541	biolink:NamedThing	fatty acid beta-oxidation, unsaturated, odd number	A fatty acid beta-oxidation pathway by which fatty acids having cis-double bonds on odd-numbered carbons are degraded. In this pathway, a cis-3-enoyl-CoA is generated by the core beta-oxidation pathway, and then converted to a trans-2-enoyl-CoA, which can return to the core beta-oxidation pathway for complete degradation. Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and ends when only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively).	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:PWY-5137									biological_process											owl:Class	
GO:1905689	biolink:NamedThing	positive regulation of diacylglycerol kinase activity	Any process that activates or increases the frequency, rate or extent of diacylglycerol kinase activity.	tmpzr1t_l9r_go_relaxed.owl	up regulation of DGK activity|up regulation of 1,2-diacylglycerol kinase activity|up regulation of ATP:diacylglycerol phosphotransferase activity|positive regulation of ATP:diacylglycerol phosphotransferase activity|activation of DG kinase activity|upregulation of diglyceride kinase activity|activation of ATP:diacylglycerol phosphotransferase activity|positive regulation of diglyceride kinase activity|up regulation of CTP:diacylglycerol kinase activity|upregulation of diacylglycerol:ATP kinase activity|up regulation of diacylglycerol:ATP kinase activity|activation of diacylglycerol:ATP kinase activity|up-regulation of DGK activity|upregulation of diacylglycerol kinase activity|up-regulation of diacylglycerol kinase activity|upregulation of ATP:diacylglycerol phosphotransferase activity|upregulation of arachidonoyl-specific diacylglycerol kinase activity|positive regulation of 1,2-diacylglycerol kinase activity|activation of DGK activity|up-regulation of sn-1,2-diacylglycerol kinase activity|up-regulation of ATP:1,2-diacylglycerol 3-phosphotransferase activity|up-regulation of CTP:diacylglycerol kinase activity|up-regulation of diacylglycerol:ATP kinase activity|upregulation of DG kinase activity|up regulation of ATP:1,2-diacylglycerol 3-phosphotransferase activity|up-regulation of 1,2-diacylglycerol kinase (phosphorylating)|up regulation of diacylglycerol kinase activity|upregulation of DGK activity|up-regulation of diglyceride kinase activity|activation of ATP:1,2-diacylglycerol 3-phosphotransferase activity|positive regulation of ATP:1,2-diacylglycerol 3-phosphotransferase activity|up regulation of sn-1,2-diacylglycerol kinase activity|upregulation of CTP:diacylglycerol kinase activity|upregulation of 1,2-diacylglycerol kinase (phosphorylating)|positive regulation of 1,2-diacylglycerol kinase (phosphorylating)|activation of sn-1,2-diacylglycerol kinase activity|up regulation of arachidonoyl-specific diacylglycerol kinase activity|up regulation of diglyceride kinase activity|positive regulation of diacylglycerol:ATP kinase activity|upregulation of sn-1,2-diacylglycerol kinase activity|positive regulation of CTP:diacylglycerol kinase activity|activation of diacylglycerol kinase activity|up-regulation of ATP:diacylglycerol phosphotransferase activity|upregulation of 1,2-diacylglycerol kinase activity|activation of 1,2-diacylglycerol kinase (phosphorylating)|activation of arachidonoyl-specific diacylglycerol kinase activity|up-regulation of DG kinase activity|positive regulation of arachidonoyl-specific diacylglycerol kinase activity|positive regulation of DG kinase activity|positive regulation of sn-1,2-diacylglycerol kinase activity|positive regulation of DGK activity|up regulation of 1,2-diacylglycerol kinase (phosphorylating)|activation of CTP:diacylglycerol kinase activity|activation of diglyceride kinase activity|up regulation of DG kinase activity|up-regulation of arachidonoyl-specific diacylglycerol kinase activity|upregulation of ATP:1,2-diacylglycerol 3-phosphotransferase activity|up-regulation of 1,2-diacylglycerol kinase activity|activation of 1,2-diacylglycerol kinase activity							bc	2016-11-14T12:26:26Z					biological_process											owl:Class	
GO:1900994	biolink:NamedThing	(-)-secologanin biosynthetic process	The chemical reactions and pathways resulting in the formation of (-)-secologanin.	tmpzr1t_l9r_go_relaxed.owl	(-)-secologanin biosynthesis|(-)-secologanin formation|(-)-secologanin anabolism|(-)-secologanin synthesis							yaf	2012-06-14T09:51:46Z					biological_process											owl:Class	
GO:0052762	biolink:NamedThing	gellan lyase activity	Catalysis of the reaction: gellan = n beta-D-4-deoxy-delta4,5-GlcAp-(1->4)-beta-D-Glcp-(1->4)-alpha-L-Rhap-(1->3)-beta-D-Glcp. This reaction is the eliminative cleavage of beta-D-glucopyranosyl-(1->4)-beta-D-glucopyranosyluronate bonds of gellan backbone, releasing tetrasaccharides containing a 4-deoxy-4,5-unsaturated D-glucopyranosyluronic acid at the non-reducing end; in the product, the abbreviations are D-glucose (Glc), D-glucuronic acid (GlcA), and L-rhamnose (Rha).	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-12269|EC:4.2.2.25			ai	2011-09-29T03:19:25Z					molecular_function											owl:Class	
GO:0003952	biolink:NamedThing	NAD+ synthase (glutamine-hydrolyzing) activity	Catalysis of the reaction: ATP + deamido-NAD+ + L-glutamine + H2O = AMP + diphosphate + NAD+ + L-glutamate.	tmpzr1t_l9r_go_relaxed.owl	NAD(+) synthetase (glutamine-hydrolyzing) activity|desamidonicotinamide adenine dinucleotide amidotransferase activity|NAD+ synthase (glutamine-hydrolysing)|NAD+ synthetase (glutamine-hydrolyzing)|NAD synthetase (glutamine-hydrolysing)|DPN synthetase activity|deamido-NAD+:L-glutamine amido-ligase (AMP-forming)|NAD synthase (glutamine-hydrolyzing) activity|nicotinamide adenine dinucleotide synthetase (glutamine) activity				Reactome:R-HSA-197271|RHEA:24384|EC:6.3.5.1|Wikipedia:NAD+_synthase_(glutamine-hydrolysing)|MetaCyc:NAD-SYNTH-GLN-RXN									molecular_function											owl:Class	
GO:0031273	biolink:NamedThing	negative regulation of pseudopodium assembly	Any process that stops, prevents, or reduces the frequency, rate or extent of the assembly of pseudopodia.	tmpzr1t_l9r_go_relaxed.owl	down regulation of pseudopodium formation|down-regulation of pseudopodium formation|inhibition of pseudopodium formation|negative regulation of pseudopodium formation|downregulation of pseudopodium formation													biological_process											owl:Class	
GO:0042459	biolink:NamedThing	octopine catabolic process to proline	The chemical reactions and pathways resulting in the breakdown of octopine into other compounds, including proline.	tmpzr1t_l9r_go_relaxed.owl	octopine breakdown to proline|octopine degradation to proline				MetaCyc:OCTOPINEDEG-PWY									biological_process											owl:Class	
GO:0018504	biolink:NamedThing	cis-1,2-dihydrobenzene-1,2-diol dehydrogenase activity	Catalysis of the reaction: cis-1,2-dihydrobenzene-1,2-diol + NAD+ = catechol + NADH + H+.	tmpzr1t_l9r_go_relaxed.owl	cis-1,2-dihydrocyclohexa-3,5-diene (nicotinamide adenine dinucleotide) oxidoreductase activity|cis-1,2-dihydrobenzene-1,2-diol:NAD+ oxidoreductase activity|cis-benzene glycol dehydrogenase activity				UM-BBD_enzymeID:e0060|MetaCyc:1.3.1.19-RXN|RHEA:15457|EC:1.3.1.19									molecular_function											owl:Class	
GO:0032931	biolink:NamedThing	histone acetyltransferase activity (H3-K56 specific)	Catalysis of the reaction: acetyl-CoA + histone H3 L-lysine (position 56) = CoA + histone H3 N6-acetyl-L-lysine (position 56).	tmpzr1t_l9r_go_relaxed.owl	histone lysine N-acetyltransferase activity (H3-K56 specific)													molecular_function											owl:Class	
GO:0055071	biolink:NamedThing	manganese ion homeostasis	Any process involved in the maintenance of an internal steady state of manganese ions within an organism or cell.	tmpzr1t_l9r_go_relaxed.owl	manganese homeostasis													biological_process											owl:Class	
GO:0050153	biolink:NamedThing	omega-hydroxydecanoate dehydrogenase activity	Catalysis of the reaction: 10-hydroxydecanoate + NAD(+) = 10-oxodecanoate + H(+) + NADH.	tmpzr1t_l9r_go_relaxed.owl	w-hydroxydecanoate dehydrogenase activity|10-hydroxydecanoate:NAD+ 10-oxidoreductase activity				KEGG_REACTION:R03886|RHEA:20880|EC:1.1.1.66|MetaCyc:OMEGA-HYDROXYDECANOATE-DEHYDROGENASE-RXN									molecular_function											owl:Class	
GO:1905022	biolink:NamedThing	negative regulation of threonine-tRNA ligase activity	Any process that stops, prevents or reduces the frequency, rate or extent of threonine-tRNA ligase activity.	tmpzr1t_l9r_go_relaxed.owl	down regulation of L-threonine:tRNAThr ligase (AMP-forming)|negative regulation of threonyl-transfer ribonucleic acid synthetase activity|down-regulation of threonyl ribonucleic synthetase activity|down regulation of threonine-tRNA ligase activity|downregulation of threonine translase activity|down regulation of threonine-transfer ribonucleate synthetase activity|inhibition of threonine translase activity|negative regulation of L-threonine:tRNAThr ligase (AMP-forming)|inhibition of threonyl-transfer ribonucleate synthetase activity|inhibition of threonyl-transfer ribonucleic acid synthetase activity|negative regulation of threonine-transfer ribonucleate synthetase activity|inhibition of threonyl ribonucleic synthetase activity|down regulation of TRS|inhibition of threonyl-tRNA synthetase activity|negative regulation of threonyl-transfer ribonucleate synthetase activity|downregulation of TRS|downregulation of threonyl-transfer RNA synthetase activity|downregulation of threonine-transfer ribonucleate synthetase activity|down regulation of threonyl-transfer ribonucleate synthetase activity|inhibition of threonine-tRNA ligase activity|down-regulation of threonyl-transfer RNA synthetase activity|downregulation of threonyl-transfer ribonucleic acid synthetase activity|down-regulation of threonyl-transfer ribonucleic acid synthetase activity|negative regulation of threonine translase activity|down-regulation of TRS|negative regulation of threonyl-transfer RNA synthetase activity|down-regulation of threonyl-transfer ribonucleate synthetase activity|downregulation of threonine-tRNA ligase activity|inhibition of threonine-transfer ribonucleate synthetase activity|negative regulation of TRS|downregulation of threonyl-transfer ribonucleate synthetase activity|down regulation of threonyl-tRNA synthetase activity|down-regulation of threonyl-tRNA synthetase activity|down regulation of threonyl-transfer RNA synthetase activity|down-regulation of threonine-tRNA ligase activity|downregulation of threonyl ribonucleic synthetase activity|down regulation of threonyl ribonucleic synthetase activity|down-regulation of L-threonine:tRNAThr ligase (AMP-forming)|downregulation of L-threonine:tRNAThr ligase (AMP-forming)|inhibition of threonyl-transfer RNA synthetase activity|down-regulation of threonine-transfer ribonucleate synthetase activity|down-regulation of threonine translase activity|inhibition of L-threonine:tRNAThr ligase (AMP-forming)|inhibition of TRS|negative regulation of threonyl ribonucleic synthetase activity|down regulation of threonyl-transfer ribonucleic acid synthetase activity|negative regulation of threonyl-tRNA synthetase activity|downregulation of threonyl-tRNA synthetase activity|down regulation of threonine translase activity							sl	2016-03-03T19:12:32Z					biological_process											owl:Class	
GO:0004166	biolink:NamedThing	dolichyl-phosphate alpha-N-acetylglucosaminyltransferase activity	Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + dolichyl phosphate = UDP + dolichyl N-acetyl-alpha-D-glucosaminyl phosphate.	tmpzr1t_l9r_go_relaxed.owl	dolichyl phosphate N-acetylglucosaminyltransferase activity|dolichyl-phosphate N-acetylglucosaminyltransferase activity|dolichyl-phosphate acetylglucosaminyltransferase activity|dolichyl phosphate acetylglucosaminyltransferase activity|uridine diphosphoacetylglucosamine-dolichol phosphate acetylglucosaminyltransferase activity|UDP-N-acetyl-D-glucosamine:dolichyl-phosphate alpha-N-acetyl-D-glucosaminyltransferase activity|UDP-N-acetylglucosamine-dolichol phosphate N-acetylglucosaminyltransferase activity				MetaCyc:2.4.1.153-RXN|EC:2.4.1.153|RHEA:14693							GO:0004101		molecular_function											owl:Class	
GO:1900655	biolink:NamedThing	regulation of diorcinol biosynthetic process	Any process that modulates the frequency, rate or extent of diorcinol biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of diorcinol formation|regulation of diorcinol anabolism|regulation of diorcinol synthesis|regulation of diorcinol biosynthesis							di	2012-05-22T04:08:40Z					biological_process											owl:Class	
GO:2000881	biolink:NamedThing	regulation of starch catabolic process	Any process that modulates the frequency, rate or extent of starch catabolic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of starch degradation|regulation of starch breakdown|regulation of starch catabolism							bf	2011-07-27T03:23:39Z					biological_process											owl:Class	
GO:0019516	biolink:NamedThing	lactate oxidation	The chemical reactions and pathways resulting in the conversion of lactate to other compounds, such as pyruvate, with concomitant loss of electrons.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0032417	biolink:NamedThing	positive regulation of sodium:proton antiporter activity	Any process that activates or increases the activity of a sodium:hydrogen antiporter, which catalyzes the reaction: Na+(out) + H+(in) = Na+(in) + H+(out).	tmpzr1t_l9r_go_relaxed.owl	upregulation of sodium:hydrogen antiporter activity|up-regulation of sodium:hydrogen antiporter activity|activation of sodium:hydrogen antiporter activity|up regulation of sodium:hydrogen antiporter activity|stimulation of sodium:hydrogen antiporter activity|positive regulation of sodium:hydrogen antiporter activity													biological_process											owl:Class	
GO:0090283	biolink:NamedThing	regulation of protein glycosylation in Golgi	Any process that modulates the rate, frequency, or extent of the addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid in any compartment of the Golgi apparatus.	tmpzr1t_l9r_go_relaxed.owl	regulation of protein amino acid glycosylation in Golgi							tb	2010-02-18T02:43:55Z					biological_process											owl:Class	
GO:0043871	biolink:NamedThing	delta1-piperideine-6-carboxylate dehydrogenase activity	Catalysis of the reaction: delta1-piperideine-6-carboxylate + NAD+ + 2 H2O = 2-aminoadipate + NADH + H+. Delta1-piperideine-6-carboxylate is also known as 2,3,4,5-tetrahydropyridine-2-carboxylate.	tmpzr1t_l9r_go_relaxed.owl	AmaB|PIPOX				MetaCyc:RXN-8162|RHEA:49476	This function is part of the pipecolate pathway of lysine catabolism.								molecular_function											owl:Class	
GO:0102331	biolink:NamedThing	heptadecanoyl-[acp] elongase/decarboxylase activity	Catalysis of the reaction: malonyl-CoA + 3 H+ + a heptodecanoyl-[acp] = octadec-1-ene + 2 carbon dioxide + coenzyme A + a holo-[acyl-carrier protein].	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-13259									molecular_function											owl:Class	
GO:0015938	biolink:NamedThing	coenzyme A catabolic process	The chemical reactions and pathways resulting in the breakdown of coenzyme A, 3'-phosphoadenosine-(5')diphospho(4')pantatheine, an acyl carrier in many acylation and acyl-transfer reactions in which the intermediate is a thiol ester.	tmpzr1t_l9r_go_relaxed.owl	CoA catabolism|coenzyme A catabolism|coenzyme A degradation|coenzyme A breakdown											GO:0006765		biological_process											owl:Class	
GO:0051539	biolink:NamedThing	4 iron, 4 sulfur cluster binding	Binding to a 4 iron, 4 sulfur (4Fe-4S) cluster; this cluster consists of four iron atoms, with the inorganic sulfur atoms found between the irons and acting as bridging ligands.	tmpzr1t_l9r_go_relaxed.owl	iron-sulphur cluster 4Fe-4S binding|tetrairon tetrasulphide cluster binding|4Fe-4S cluster binding|iron-sulfur cluster 4Fe-4S binding|tetrairon tetrasulfide cluster binding|4 Fe 4 S cluster binding|4 iron, 4 sulphur cluster binding													molecular_function											owl:Class	
GO:0051536	biolink:NamedThing	iron-sulfur cluster binding	Binding to an iron-sulfur cluster, a combination of iron and sulfur atoms.	tmpzr1t_l9r_go_relaxed.owl	iron sulfur cluster binding|Fe/S binding|iron sulphur cluster binding|iron-sulphur cluster binding													molecular_function											owl:Class	
GO:0061797	biolink:NamedThing	pH-gated chloride channel activity	A gated channel activity that enables the transmembrane transfer of a chloride ion by a channel that opens in response to a change in pH.	tmpzr1t_l9r_go_relaxed.owl								dph	2016-10-06T07:11:14Z					molecular_function											owl:Class	
GO:0034026	biolink:NamedThing	L-amino-acid alpha-ligase activity	Catalysis of the reaction: ATP + an L-amino acid + an L-amino acid = ADP + phosphate + L-aminoacyl-L-amino acid.	tmpzr1t_l9r_go_relaxed.owl	YwfE|bacilysin synthetase activity|L-amino acid ligase activity|L-amino acid alpha-ligase activity				MetaCyc:6.3.2.28-RXN|RHEA:44332|EC:6.3.2.49									molecular_function											owl:Class	
GO:2000074	biolink:NamedThing	regulation of type B pancreatic cell development	Any process that modulates the frequency, rate or extent of pancreatic B cell development.	tmpzr1t_l9r_go_relaxed.owl	regulation of pancreatic beta cell development|regulation of pancreatic B cell development							tb	2010-08-27T11:19:37Z					biological_process											owl:Class	
GO:0034464	biolink:NamedThing	BBSome	A ciliary protein complex involved in cilium biogenesis. It consists of at least seven Bardet-Biedl syndrome (BBS) proteins and BBIP10. It moves in association with IFT trains through cilia (likely as an IFT-A/B adaptor or cargo), and is required for the integrity of IFT-A and IFT-B.	tmpzr1t_l9r_go_relaxed.owl	Bardet-Biedl syndrome complex													cellular_component											owl:Class	
GO:1904216	biolink:NamedThing	positive regulation of protein import into chloroplast stroma	Any process that activates or increases the frequency, rate or extent of protein import into chloroplast stroma.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of protein import into chloroplast stroma|activation of chloroplast stroma protein import|up-regulation of protein transport into chloroplast stroma|activation of protein import into chloroplast stroma|up regulation of protein transport into chloroplast stroma|up regulation of protein import into chloroplast stroma|activation of protein transport into chloroplast stroma|up-regulation of chloroplast stroma protein import|upregulation of protein transport into chloroplast stroma|upregulation of chloroplast stroma protein import|positive regulation of chloroplast stroma protein import|positive regulation of protein transport into chloroplast stroma|upregulation of protein import into chloroplast stroma|up regulation of chloroplast stroma protein import							tb	2015-05-15T00:47:55Z					biological_process											owl:Class	
GO:0010376	biolink:NamedThing	stomatal complex formation	The process that gives rise to the stomatal complex. This process pertains to the initial formation of a structure from unspecified parts. The stomatal complex is the stomatal guard cells and their associated epidermal cells.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0033046	biolink:NamedThing	negative regulation of sister chromatid segregation	Any process that stops, prevents, or reduces the frequency, rate or extent of sister chromatid segregation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0004322	biolink:NamedThing	ferroxidase activity	Catalysis of the reaction: 4 Fe2+ + 4 H+ + O2 = 4 Fe3+ + 2 H2O.	tmpzr1t_l9r_go_relaxed.owl	HEPH|iron(II): oxygen oxidoreductase activity|multicopper ferroxidase iron transport mediator activity|ceruloplasmin|Fe(II):oxygen oxidoreductase activity|caeruloplasmin|ferroxidase, iron II:oxygen oxidoreductase activity|ferro:O2 oxidoreductase activity|ferroxidase I|hephaestin	https://github.com/geneontology/go-ontology/issues/20675			Reactome:R-HSA-5621402|Reactome:R-HSA-917891|Reactome:R-HSA-1562626|MetaCyc:RXN0-1483|Reactome:R-HSA-5691107|Reactome:R-HSA-1562604|Reactome:R-HSA-917933|Reactome:R-HSA-1562603|EC:1.16.3.1|RHEA:11148									molecular_function											owl:Class	
GO:0016724	biolink:NamedThing	oxidoreductase activity, acting on metal ions, oxygen as acceptor	Catalysis of an oxidation-reduction in which the oxidation state of metal ion is altered and oxygen acts as an electron acceptor.	tmpzr1t_l9r_go_relaxed.owl	oxidoreductase activity, oxidizing metal ions, oxygen as acceptor	https://github.com/geneontology/go-ontology/issues/20682			EC:1.16.3.-									molecular_function											owl:Class	
GO:0030546	biolink:NamedThing	signaling receptor activator activity	The function of interacting (directly or indirectly) with receptors such that the proportion of receptors in the active form is increased.	tmpzr1t_l9r_go_relaxed.owl	signalling receptor activator activity|receptor activator activity													molecular_function											owl:Class	
GO:1905422	biolink:NamedThing	negative regulation of plant organ morphogenesis	Any process that stops, prevents or reduces the frequency, rate or extent of plant organ morphogenesis.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of plant organ morphogenesis|inhibition of plant organ morphogenesis|down regulation of plant organ morphogenesis|downregulation of plant organ morphogenesis							tb	2016-09-06T23:00:22Z					biological_process											owl:Class	
GO:2000923	biolink:NamedThing	positive regulation of arabinoxylan-containing compound catabolic process	Any process that activates or increases the frequency, rate or extent of arabinoxylan-containing compound catabolic process.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of arabinoxylan catabolism							tt	2011-08-01T12:39:02Z					biological_process											owl:Class	
GO:0005277	biolink:NamedThing	acetylcholine transmembrane transporter activity	Enables the transfer of acetylcholine from one side of a membrane to the other. Acetylcholine is an acetic acid ester of the organic base choline and functions as a neurotransmitter, released at the synapses of parasympathetic nerves and at neuromuscular junctions.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-264615									molecular_function											owl:Class	
GO:0005326	biolink:NamedThing	neurotransmitter transmembrane transporter activity	Enables the directed movement of a neurotransmitter into, out of or within a cell, or between cells. Neurotransmitters are any chemical substance that is capable of transmitting (or inhibiting the transmission of) a nerve impulse from a neuron to another cell.	tmpzr1t_l9r_go_relaxed.owl	neurotransmitter transporter activity				Reactome:R-HSA-374896|Reactome:R-HSA-374919									molecular_function											owl:Class	
GO:0061955	biolink:NamedThing	positive regulation of actin filament depolymerization involved in acrosome reaction	Any process that increases the rate or exent of actin depolymerization as part of the acrosome reaction. This allows the acrosomal membrane and plasma membrane to fuse.	tmpzr1t_l9r_go_relaxed.owl								dph	2017-11-10T19:43:18Z					biological_process											owl:Class	
GO:0030836	biolink:NamedThing	positive regulation of actin filament depolymerization	Any process that activates or increases the frequency, rate or extent of actin depolymerization.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of actin polymerization and/or depolymerization|positive regulation of actin depolymerization|stimulation of actin filament depolymerization|up-regulation of actin filament depolymerization|actin filament destabilization|activation of actin filament depolymerization|up regulation of actin filament depolymerization|upregulation of actin filament depolymerization					Note that this term was split from 'positive regulation of actin polymerization and/or depolymerization ; GO:0045758' (sibling term 'positive regulation of actin polymerization ; GO:0030838').						GO:0030045		biological_process											owl:Class	
GO:0052131	biolink:NamedThing	positive aerotaxis	The directed movement of a motile cell or organism towards a higher concentration of environmental oxygen.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0009454	biolink:NamedThing	aerotaxis	The directed movement of a motile cell or organism in response to environmental oxygen.	tmpzr1t_l9r_go_relaxed.owl	taxis in response to atmospheric oxygen													biological_process											owl:Class	
GO:1990179	biolink:NamedThing	protein localization to actomyosin contractile ring	A process in which a protein is transported to, or maintained at, the actomyosin contractile ring.	tmpzr1t_l9r_go_relaxed.owl	protein localisation to actomyosin contractile ring							mah	2013-08-30T16:13:54Z					biological_process											owl:Class	
GO:0120280	biolink:NamedThing	ciliary pro-basal body	The cilary pro-basal body is an immature, partially assembled form of a ciliary basal body found next to the basal body of a cilium. Pro-basal bodies are not capable of nucleating a cilium. As the cell progresses through the cell cycle, continuing assembly will convert the pro-basal body into a mature basal body that is capable of nucleating a cilium.	tmpzr1t_l9r_go_relaxed.owl	flagellar probasal body|pro-basal body|flagellar pro-basal body|probasal body|pro-centriole	https://github.com/geneontology/go-ontology/issues/14963				Pro-basal bodies are distinct from basal bodies as they are not at the base of a cilium and are not capable of nucleating a cilium. While immature, they contain some structures in common with the mature basal body and also may contain proteins unique to the immature state. Note that cilia and eukaryotic flagella are deemed to be equivalent. In many eukaryotic cells, 'ciliary basal body' (GO:0036064) and 'centriole' (GO:0005814) represent a common entity that cycles through its function in cell division, then ciliogenesis, then cell division again. However, these structures are modified extensively as they transition into each other, and may contain different proteins, specific to each component. In other eukaryotic cells, centrioles are not involved in cell division but only in cilium assembly, which is thought to be the ancestral role of the centriole/basal body.		krc	2020-10-29T22:54:44Z					cellular_component											owl:Class	
GO:1901523	biolink:NamedThing	icosanoid catabolic process	The chemical reactions and pathways resulting in the breakdown of icosanoid.	tmpzr1t_l9r_go_relaxed.owl	icosanoid breakdown|icosanoid catabolism|icosanoid degradation							pr	2012-10-22T10:50:09Z					biological_process											owl:Class	
GO:1900365	biolink:NamedThing	positive regulation of mRNA polyadenylation	Any process that activates or increases the frequency, rate or extent of mRNA polyadenylation.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of mRNA polyadenylylation|positive regulation of cleavage and polyadenylylation specificity factor activity|activation of mRNA polyadenylation|upregulation of mRNA polyadenylation|activation of mRNA polyadenylylation|up-regulation of cleavage and polyadenylylation specificity factor activity|upregulation of cleavage and polyadenylylation specificity factor activity|upregulation of mRNA polyadenylylation|up regulation of mRNA polyadenylylation|activation of cleavage and polyadenylylation specificity factor activity|up-regulation of mRNA polyadenylation|up regulation of mRNA polyadenylation|up-regulation of mRNA polyadenylylation|up regulation of cleavage and polyadenylylation specificity factor activity							pr	2012-04-12T04:36:39Z					biological_process											owl:Class	
GO:1903356	biolink:NamedThing	positive regulation of distal tip cell migration	Any process that activates or increases the frequency, rate or extent of distal tip cell migration.	tmpzr1t_l9r_go_relaxed.owl	upregulation of distal tip cell migration|activation of distal tip cell migration|up regulation of distal tip cell migration|up-regulation of distal tip cell migration							pr	2014-08-21T10:05:26Z					biological_process											owl:Class	
GO:0002533	biolink:NamedThing	lysosomal enzyme secretion involved in inflammatory response	The regulated release of lysosomal enzymes by a cell as part of an inflammatory response.	tmpzr1t_l9r_go_relaxed.owl	secretion of lysosomal enzymes involved in inflammatory response|secretion of lysosomal enzymes involved in acute inflammatory response|lysosomal enzyme secretion involved in acute inflammatory response													biological_process											owl:Class	
GO:0033299	biolink:NamedThing	secretion of lysosomal enzymes	The controlled release of lysosomal enzymes by a cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0002479	biolink:NamedThing	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent	The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class I protein complex following intracellular transport via a TAP (transporter associated with antigen processing) pathway. The peptide is typically a fragment of a larger exogenous protein which has been degraded within the cell and is dependent on TAP transport from the cytosol to ER for association with the MHC class I molecule. Class I here refers to classical class I molecules.	tmpzr1t_l9r_go_relaxed.owl	TAP-dependent exogenous peptide antigen processing and presentation via MHC class I|TAP-dependent antigen processing and presentation of exogenous peptide antigen via MHC class I|exogenous peptide antigen processing and presentation via MHC class I, TAP-dependent|cross-presentation|cross presentation													biological_process											owl:Class	
GO:0019475	biolink:NamedThing	L-lysine catabolic process to acetate	The chemical reactions and pathways resulting in the breakdown of L-lysine into other compounds, including acetate.	tmpzr1t_l9r_go_relaxed.owl	L-lysine breakdown to acetate|L-lysine degradation to acetate|lysine fermentation				MetaCyc:P163-PWY									biological_process											owl:Class	
GO:0102151	biolink:NamedThing	3-oxo-myristate decarboxylase activity	Catalysis of the reaction: 3-oxo-myristate + H+ <=> 2-tridecanone + carbon dioxide.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-11669|EC:4.1.1.56									molecular_function											owl:Class	
GO:1903288	biolink:NamedThing	positive regulation of potassium ion import across plasma membrane	Any process that activates or increases the frequency, rate or extent of potassium ion import across the plasma membrane.	tmpzr1t_l9r_go_relaxed.owl	activation of potassium ion uptake|up-regulation of potassium ion uptake|upregulation of potassium ion uptake|positive regulation of potassium ion uptake|upregulation of potassium import|activation of potassium import|up regulation of potassium import|activation of potassium ion import|up-regulation of potassium ion import|up regulation of potassium ion import|up regulation of potassium ion uptake|upregulation of potassium ion import|positive regulation of potassium ion import|up-regulation of potassium import|positive regulation of potassium import							rl	2014-08-11T14:26:32Z					biological_process											owl:Class	
GO:1905768	biolink:NamedThing	negative regulation of double-stranded telomeric DNA binding	Any process that stops, prevents or reduces the frequency, rate or extent of double-stranded telomeric DNA binding.	tmpzr1t_l9r_go_relaxed.owl	down regulation of double-stranded telomeric DNA binding|downregulation of double-stranded telomeric DNA binding|inhibition of double-stranded telomeric DNA binding|down-regulation of double-stranded telomeric DNA binding							nc	2016-12-20T15:34:07Z					biological_process											owl:Class	
GO:0070807	biolink:NamedThing	positive regulation of phialide development	Any process that activates or increases the frequency, rate or extent of phialide development, a process that leads to the formation of phialides. Phialides are specialized cells that bud from the ends of metulae on the conidiophore tip.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-07-08T04:48:08Z					biological_process											owl:Class	
GO:0052665	biolink:NamedThing	tRNA (uracil-2'-O-)-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing 2'-O-methyluracil.	tmpzr1t_l9r_go_relaxed.owl	S-adenosyl-L-methionine:tRNA (uracil-2'-O-)-methyltransferase activity|S-adenosyl-L-methionine:tRNA uracil-2'-O-methyltransferase activity|tRNA uracil 2'-methyltransferase activity|tRNA (uracil 2')-methyltransferase activity|transfer ribonucleate uracil 2'-methyltransferase activity|tRNA uracil-2'-O-methyltransferase activity				EC:2.1.1.34|RHEA:43100|Reactome:R-HSA-6788707|MetaCyc:RXN0-5143			ai	2010-10-11T01:05:35Z					molecular_function											owl:Class	
GO:0099240	biolink:NamedThing	intrinsic component of synaptic membrane	The component of the synaptic membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.	tmpzr1t_l9r_go_relaxed.owl	intrinsic to synaptic membrane							dos	2017-05-25T17:23:21Z					cellular_component											owl:Class	
GO:1904829	biolink:NamedThing	regulation of aortic smooth muscle cell differentiation	Any process that modulates the frequency, rate or extent of aortic smooth muscle cell differentiation.	tmpzr1t_l9r_go_relaxed.owl								rph	2015-11-24T10:20:40Z					biological_process											owl:Class	
GO:0043609	biolink:NamedThing	regulation of carbon utilization	Any process that modulates the frequency, rate, or extent of carbon utilization.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0001165	biolink:NamedThing	RNA polymerase I cis-regulatory region sequence-specific DNA binding	Binding to a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site) located in cis relative to the transcription start site (i.e., on the same strand of DNA) of a gene transcribed by RNA polymerase I. RNA polymerase I elements are referred to either enhancers or upstream control element (UCE, or alternately referred to as the upstream element).	tmpzr1t_l9r_go_relaxed.owl	RNA polymerase I enhancer sequence-specific DNA binding|RNA polymerase I upstream control element sequence-specific DNA binding|RNA polymerase I upstream element sequence-specific DNA binding							krc	2011-01-31T05:29:59Z			GO:0001166		molecular_function											owl:Class	
GO:0001163	biolink:NamedThing	RNA polymerase I transcription regulatory region sequence-specific DNA binding	Binding to a specific sequence of DNA that is part of a regulatory region that controls the transcription of a gene or cistron by RNA polymerase I.	tmpzr1t_l9r_go_relaxed.owl	RNA polymerase I regulatory region DNA binding	https://github.com/geneontology/go-ontology/issues/19312						krc	2011-01-31T04:12:06Z			GO:0001013		molecular_function											owl:Class	
GO:0007629	biolink:NamedThing	flight behavior	The response to external or internal stimuli that results in the locomotory process of flight. Flight is the self-propelled movement of an organism through the air.	tmpzr1t_l9r_go_relaxed.owl	flight behaviour													biological_process											owl:Class	
GO:0072013	biolink:NamedThing	glomus development	The progression of the glomus over time from its initial formation until its mature state. The glomus forms from the splanchnic intermediate mesoderm and is the vascularized filtration unit, filtering the blood before it enters the tubules. The glomus is external to the nephron and extends over more than one body segment.	tmpzr1t_l9r_go_relaxed.owl	pronephric glomus development							mah	2010-01-25T02:23:19Z					biological_process											owl:Class	
GO:0010976	biolink:NamedThing	positive regulation of neuron projection development	Any process that increases the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites).	tmpzr1t_l9r_go_relaxed.owl	positive regulation of neurite growth|positive regulation of neurite biosynthesis|positive regulation of neurite development|positive regulation of neurite formation							tb	2009-06-01T10:46:44Z					biological_process											owl:Class	
GO:0007008	biolink:NamedThing	outer mitochondrial membrane organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the mitochondrial outer membrane.	tmpzr1t_l9r_go_relaxed.owl	outer mitochondrial membrane organization and biogenesis|outer mitochondrial membrane organisation					See also the cellular component term 'mitochondrial outer membrane ; GO:0005741'.								biological_process											owl:Class	
GO:0051687	biolink:NamedThing	maintenance of spindle location	Any process in which the spindle is maintained in a specific location within a cell and prevented from moving elsewhere.	tmpzr1t_l9r_go_relaxed.owl	maintenance of spindle localization													biological_process											owl:Class	
GO:0046834	biolink:NamedThing	lipid phosphorylation	The process of introducing one or more phosphate groups into a lipid, any member of a group of substances soluble in lipid solvents but only sparingly soluble in aqueous solvents.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0097561	biolink:NamedThing	right caudal flagellum	A cilium (also called flagellum) found in Giardia species (trophozoite stage). It is nucleated by the right caudal basal body, extending cytoplasmically and exiting at the posterior end of the cell body.	tmpzr1t_l9r_go_relaxed.owl	right caudal cilium					Note that we deem cilium and microtubule-based flagellum to be equivalent; the primary term name reflects frequency of use. Also note that, due to the asymmetric nature of the Giardia trophozoite, this term is defined spatially as the trophozoite is viewed from the dorsal side, with the two nuclei dorsal to the ventral disc, and the ventral disc toward the anterior.		pr	2014-02-05T13:31:15Z					cellular_component											owl:Class	
GO:0003922	biolink:NamedThing	GMP synthase (glutamine-hydrolyzing) activity	Catalysis of the reaction: ATP + XMP + L-glutamine + H2O = AMP + diphosphate + GMP + L-glutamate + 2H(+).	tmpzr1t_l9r_go_relaxed.owl	GMP synthetase (glutamine-hydrolyzing) activity|xanthosine-5'-phosphate:L-glutamine amido-ligase (AMP-forming)|guanosine 5'-monophosphate synthetase activity|glutamine amidotransferase activity|guanosine monophosphate synthetase (glutamine-hydrolyzing)|guanylate synthetase (glutamine-hydrolyzing)|GMP synthase (glutamine-hydrolysing)|xanthosine 5'-phosphate amidotransferase activity|GMP synthetase (glutamine-hydrolysing)				MetaCyc:GMP-SYN-GLUT-RXN|EC:6.3.5.2|RHEA:11680|Wikipedia:GMP_synthase_(glutamine-hydrolysing)|Reactome:R-HSA-73792									molecular_function											owl:Class	
GO:0005122	biolink:NamedThing	torso binding	Binding to a torso (tor) protein, a receptor tyrosine kinase.	tmpzr1t_l9r_go_relaxed.owl	torso ligand|tor binding|tor ligand													molecular_function											owl:Class	
GO:0047344	biolink:NamedThing	glucose-1-phosphate guanylyltransferase activity	Catalysis of the reaction: alpha-D-glucose 1-phosphate + GTP = diphosphate + GDP-D-glucose.	tmpzr1t_l9r_go_relaxed.owl	GDP glucose pyrophosphorylase activity|GDP-glucose pyrophosphorylase activity|GTP:alpha-D-glucose-1-phosphate guanylyltransferase activity|GTP:glucose-1-phosphate guanylyltransferase activity|guanosine diphosphoglucose pyrophosphorylase activity|GDP-glucose diphosphorylase activity				MetaCyc:2.7.7.34-RXN|EC:2.7.7.34|RHEA:10708|KEGG_REACTION:R00954									molecular_function											owl:Class	
GO:0102104	biolink:NamedThing	demethoxycurcumin synthase activity	Catalysis of the reaction: (4-coumaroyl)acetyl-CoA + feruloyl-CoA + H2O <=> demethoxycurcumin + 2 coenzyme A + carbon dioxide.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-11224									molecular_function											owl:Class	
GO:1902009	biolink:NamedThing	positive regulation of toxin transport	Any process that activates or increases the frequency, rate or extent of toxin transport.	tmpzr1t_l9r_go_relaxed.owl	activation of toxin transport|up regulation of toxin transport|upregulation of toxin transport|up-regulation of toxin transport							dph	2013-03-22T12:54:09Z					biological_process											owl:Class	
GO:0060370	biolink:NamedThing	susceptibility to T cell mediated cytotoxicity	The process of causing a cell to become susceptible to T cell mediated cytotoxicity.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0070649	biolink:NamedThing	formin-nucleated actin cable assembly	The aggregation, arrangement and bonding together of a set of components to form a formin-nucleated actin cable. A formin-nucleated actin cable is an actin filament bundle that consists of short filaments organized into bundles of uniform polarity, and is nucleated by formins.	tmpzr1t_l9r_go_relaxed.owl	formin-nucleated actin cable formation							mah	2009-05-12T02:14:36Z					biological_process											owl:Class	
GO:0110009	biolink:NamedThing	formin-nucleated actin cable organization	A process that results in the assembly, arrangement of constituent parts, or disassembly of a formin-nucleated actin cable.	tmpzr1t_l9r_go_relaxed.owl								kmv						biological_process											owl:Class	
GO:0097500	biolink:NamedThing	receptor localization to non-motile cilium	A process in which a receptor is transported to, or maintained in, a location within a non-motile cilium.	tmpzr1t_l9r_go_relaxed.owl	receptor localization to nonmotile primary cilium							pr	2013-08-13T12:17:34Z					biological_process											owl:Class	
GO:1990850	biolink:NamedThing	H-gal-GP complex	A membrane glycoprotein complex with aspartyl proteinase and metalloproteinase activity which is expressed in the gut. An example of this is found in the nematode Haemonchus contortus.	tmpzr1t_l9r_go_relaxed.owl	galactose-containing glycoprotein complex|Haemonchus galactose-containing glycoprotein complex							jl	2015-09-10T16:40:39Z					cellular_component											owl:Class	
GO:0032670	biolink:NamedThing	regulation of interleukin-26 production	Any process that modulates the frequency, rate, or extent of interleukin-26 production.	tmpzr1t_l9r_go_relaxed.owl	regulation of interleukin-26 biosynthetic process|regulation of IL-26 production											GO:0045530		biological_process											owl:Class	
GO:0004637	biolink:NamedThing	phosphoribosylamine-glycine ligase activity	Catalysis of the reaction: 5-phospho-D-ribosylamine + ATP + glycine = N(1)-(5-phospho-D-ribosyl)glycinamide + ADP + 2 H(+) + phosphate.	tmpzr1t_l9r_go_relaxed.owl	phosphoribosylglycinamide synthetase activity|5-phospho-D-ribosylamine:glycine ligase (ADP-forming)|5'-phosphoribosylglycinamide synthetase activity|glycineamide ribonucleotide synthetase activity|GAR|glycinamide ribonucleotide synthetase activity|GARS activity|phosphoribosylglycineamide synthetase activity|GAR synthetase activity|2-amino-N-ribosylacetamide 5'-phosphate kinosynthase activity				RHEA:17453|Reactome:R-HSA-73814|MetaCyc:GLYRIBONUCSYN-RXN|KEGG_REACTION:R04144|EC:6.3.4.13									molecular_function											owl:Class	
GO:0032790	biolink:NamedThing	ribosome disassembly	The disaggregation of a ribosome into its constituent components; includes the dissociation of ribosomal subunits.	tmpzr1t_l9r_go_relaxed.owl	ribosome recycling|ribosome dissociation factor													biological_process											owl:Class	
GO:0006865	biolink:NamedThing	amino acid transport	The directed movement of amino acids, organic acids containing one or more amino substituents, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl												GO:0006866		biological_process											owl:Class	
GO:0014039	biolink:NamedThing	negative regulation of Schwann cell differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of Schwann cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	down regulation of Schwann cell differentiation|down-regulation of Schwann cell differentiation|inhibition of Schwann cell differentiation|downregulation of Schwann cell differentiation													biological_process											owl:Class	
GO:0014038	biolink:NamedThing	regulation of Schwann cell differentiation	Any process that modulates the frequency, rate or extent of Schwann cell differentiation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0061294	biolink:NamedThing	mesonephric renal vesicle induction	Signaling at short range between cells of the ureteric bud terminus and the kidney mesenchyme that positively regulates the formation of the mesonephric renal vesicle.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-09-03T12:57:59Z					biological_process											owl:Class	
GO:1901106	biolink:NamedThing	tetracenomycin C biosynthetic process	The chemical reactions and pathways resulting in the formation of tetracenomycin C.	tmpzr1t_l9r_go_relaxed.owl	tetracenomycin C anabolism|tetracenomycin C synthesis|tetracenomycin C biosynthesis|tetracenomycin C formation							yaf	2012-07-11T02:51:03Z					biological_process											owl:Class	
GO:0017180	biolink:NamedThing	peptidyl-diphthine biosynthetic process from peptidyl-histidine	The chemical reactions and pathways resulting in the formation of peptidyl-diphthine from other compounds, including peptidyl-histidine.	tmpzr1t_l9r_go_relaxed.owl	peptidyl-diphthine anabolism from peptidyl-histidine|peptidyl-diphthine formation from peptidyl-histidine|peptidyl-diphthine synthesis from peptidyl-histidine													biological_process											owl:Class	
GO:0052472	biolink:NamedThing	modulation by host of symbiont transcription	Any process in which an organism modulates the frequency, rate or extent of its symbiont's transcription.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0102761	biolink:NamedThing	eriodictyol 3'-O-methyltransferase activity	Catalysis of the reaction: eriodictyol + S-adenosyl-L-methionine  <=> H+ + homoeriodictyol + S-adenosyl-L-homocysteine.	tmpzr1t_l9r_go_relaxed.owl					RHEA:60948|MetaCyc:RXN-7753									molecular_function											owl:Class	
GO:0019480	biolink:NamedThing	L-alanine oxidation to pyruvate via D-alanine	The chemical reactions and pathways resulting in the breakdown of L-alanine to pyruvate, with D-alanine as an intermediate.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:ALADEG-PWY									biological_process											owl:Class	
GO:0004359	biolink:NamedThing	glutaminase activity	Catalysis of the reaction: L-glutamine + H2O = L-glutamate + NH3.	tmpzr1t_l9r_go_relaxed.owl	glutamine aminohydrolase activity|L-glutamine amidohydrolase activity|glutaminase I|L-glutaminase activity				Reactome:R-HSA-70609|RHEA:15889|EC:3.5.1.2|MetaCyc:GLUTAMIN-RXN									molecular_function											owl:Class	
GO:0050193	biolink:NamedThing	phosphoketolase activity	Catalysis of the reaction: D-xylulose 5-phosphate + phosphate = acetyl phosphate + D-glyceraldehyde 3-phosphate + H2O.	tmpzr1t_l9r_go_relaxed.owl	D-xylulose-5-phosphate D-glyceraldehyde-3-phosphate-lyase (adding phosphate; acetyl-phosphate-forming)|D-xylulose-5-phosphate D-glyceraldehyde-3-phosphate-lyase (phosphate-acetylating) activity|xylulose-5-phosphate phosphoketolase activity				MetaCyc:PHOSPHOKETOLASE-RXN|EC:4.1.2.9|RHEA:10468									molecular_function											owl:Class	
GO:1900308	biolink:NamedThing	positive regulation of maltoheptaose transport	Any process that activates or increases the frequency, rate or extent of maltoheptaose transport.	tmpzr1t_l9r_go_relaxed.owl	up regulation of maltoheptaose transport|activation of maltoheptaose transport|upregulation of maltoheptaose transport|up-regulation of maltoheptaose transport							tt	2012-04-05T07:58:35Z					biological_process											owl:Class	
GO:1900296	biolink:NamedThing	positive regulation of heptasaccharide transport	Any process that activates or increases the frequency, rate or extent of heptasaccharide transport.	tmpzr1t_l9r_go_relaxed.owl	upregulation of heptasaccharide transport|up regulation of heptasaccharide transport|activation of heptasaccharide transport|up-regulation of heptasaccharide transport							tt	2012-04-05T07:40:58Z					biological_process											owl:Class	
GO:0106370	biolink:NamedThing	protein-L-histidine N-pros-methyltransferase activity	Catalysis of the reaction: L-histidyl-[protein] + S-adenosyl-L-methionine = N(pros)-methyl-L-histidyl-[protein] + S-adenosyl-L-homocysteine.	tmpzr1t_l9r_go_relaxed.owl					RHEA:67076			hjd	2021-03-22T15:13:06Z					molecular_function											owl:Class	
GO:1990546	biolink:NamedThing	mitochondrial tricarboxylic acid transmembrane transport	The process in which a tricarboxylic acid is transported across a mitochondrial membrane, into or out of the mitochondrion.	tmpzr1t_l9r_go_relaxed.owl								vw	2014-11-19T12:00:14Z					biological_process											owl:Class	
GO:0035674	biolink:NamedThing	tricarboxylic acid transmembrane transport	The process in which a tricarboxylic acid is transported across a membrane.	tmpzr1t_l9r_go_relaxed.owl	tricarboxylic acid membrane transport					Note that this term is not intended for use in annotating lateral movement within membranes.		bf	2011-02-08T02:37:31Z					biological_process											owl:Class	
GO:1903183	biolink:NamedThing	negative regulation of SUMO transferase activity	Any process that stops, prevents or reduces the frequency, rate or extent of SUMO ligase activity.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of SUMO conjugating enzyme activity|inhibition of SUMO ligase activity|inhibition of SMT3 conjugating enzyme|negative regulation of SMT3 conjugating enzyme|down regulation of SUMO conjugating enzyme activity|down regulation of SMT3 conjugating enzyme|down regulation of SUMO ligase activity|inhibition of SUMO conjugating enzyme activity|downregulation of SMT3 conjugating enzyme|downregulation of SUMO ligase activity|negative regulation of SUMO conjugating enzyme activity|down-regulation of SUMO ligase activity|downregulation of SUMO conjugating enzyme activity|down-regulation of SMT3 conjugating enzyme							bf	2014-07-14T14:01:46Z					biological_process											owl:Class	
GO:0033234	biolink:NamedThing	negative regulation of protein sumoylation	Any process that stops, prevents, or reduces the frequency, rate or extent of the addition of SUMO groups to a protein.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of sumoylation													biological_process											owl:Class	
GO:1904346	biolink:NamedThing	positive regulation of gastric mucosal blood circulation	Any process that activates or increases the frequency, rate or extent of gastric mucosal blood circulation.	tmpzr1t_l9r_go_relaxed.owl	upregulation of stomach mucosal blood circulation|up regulation of stomach mucosal blood circulation|activation of stomach mucosal blood circulation|up-regulation of stomach mucosal blood circulation|upregulation of gastric mucosal blood circulation|up-regulation of gastric mucosal blood circulation|positive regulation of stomach mucosal blood circulation|up regulation of gastric mucosal blood circulation|activation of gastric mucosal blood circulation							sl	2015-06-11T21:20:50Z					biological_process											owl:Class	
GO:0005245	biolink:NamedThing	voltage-gated calcium channel activity	Enables the transmembrane transfer of a calcium ion by a voltage-gated channel. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.	tmpzr1t_l9r_go_relaxed.owl	depolarization-activated voltage gated calcium channel activity|voltage gated calcium channel activity|depolarization-activated voltage-gated calcium channel activity|voltage-dependent calcium channel activity|voltage-gated calcium ion channel activity|depolarization-activated calcium channel|depolarization-activated voltage-gated calcium channel|dihydropyridine-sensitive calcium channel activity|voltage-sensitive calcium channel				Reactome:R-HSA-9701141|Reactome:R-HSA-5577213|Reactome:R-HSA-9701055|Reactome:R-HSA-265645							GO:0010173|GO:0015270		molecular_function											owl:Class	
GO:0007637	biolink:NamedThing	proboscis extension reflex	The extension, through direct muscle actions, of the proboscis (the trunk-like extension of the mouthparts on the adult external head) in response to a nutritional stimulus.	tmpzr1t_l9r_go_relaxed.owl	proboscis extension in response to nutritional stimulus|behavioral response to nutritional stimulus, proboscis extension													biological_process											owl:Class	
GO:0051780	biolink:NamedThing	behavioral response to nutrient	Any process that results in a change in the behavior of an organism as a result of a nutrient stimulus.	tmpzr1t_l9r_go_relaxed.owl	behavioural response to nutrient													biological_process											owl:Class	
GO:0009142	biolink:NamedThing	nucleoside triphosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of a nucleoside triphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with triphosphate on the sugar.	tmpzr1t_l9r_go_relaxed.owl	nucleoside triphosphate synthesis|nucleoside triphosphate anabolism|nucleoside triphosphate biosynthesis|nucleoside triphosphate formation													biological_process											owl:Class	
GO:0000434	biolink:NamedThing	carbon catabolite repression of transcription from RNA polymerase II promoter by galactose	Any process involving galactose that stops, prevents or reduces the rate of transcription from an RNA polymerase II promoter.	tmpzr1t_l9r_go_relaxed.owl	downregulation of transcription from RNA polymerase II promoter by galactose|down-regulation of transcription from RNA polymerase II promoter by galactose|down regulation of transcription from RNA polymerase II promoter by galactose|inhibition of transcription from RNA polymerase II promoter by galactose													biological_process											owl:Class	
GO:0000761	biolink:NamedThing	conjugant formation	During conjugation without cellular fusion, the process that results in pairing complementary mating types. Localized morphological, cytological, and cytoskeletal changes connect the mating types without cytoplasmic mixing.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1905721	biolink:NamedThing	mitotic spindle astral microtubule end	Any microtubule end that is part of a mitotic spindle astral microtubule.	tmpzr1t_l9r_go_relaxed.owl	mitotic spindle astral microtubule tip							vw	2016-11-25T12:26:18Z					cellular_component											owl:Class	
GO:0102370	biolink:NamedThing	lupeol 28-monooxygenase activity	Catalysis of the reaction: lupeol + NADPH(4-) + O2 + H+ <=> betulin + NADP(3-) + H2O.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-13497									molecular_function											owl:Class	
GO:1900780	biolink:NamedThing	fumiquinazoline C catabolic process	The chemical reactions and pathways resulting in the breakdown of fumiquinazoline C.	tmpzr1t_l9r_go_relaxed.owl	fumiquinazoline C degradation|fumiquinazoline C catabolism|fumiquinazoline C breakdown							di	2012-06-04T09:30:51Z					biological_process											owl:Class	
GO:1900779	biolink:NamedThing	fumiquinazoline C metabolic process	The chemical reactions and pathways involving fumiquinazoline C.	tmpzr1t_l9r_go_relaxed.owl	fumiquinazoline C metabolism							di	2012-06-04T09:30:30Z					biological_process											owl:Class	
GO:0034125	biolink:NamedThing	negative regulation of MyD88-dependent toll-like receptor signaling pathway	Any process that stops, prevents, or reduces the frequency, rate, or extent of MyD88-dependent toll-like receptor signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of MyD88-dependent toll-like receptor signalling pathway|negative regulation of MyD88-dependent TLR signaling pathway													biological_process											owl:Class	
GO:0034753	biolink:NamedThing	nuclear aryl hydrocarbon receptor complex	An aryl hydrocarbon receptor (AhR) complex found in the nucleus; ; consists of ligand-bound AhR and the aryl hydrocarbon receptor nuclear translocator (ARNT).	tmpzr1t_l9r_go_relaxed.owl	nuclear AHRC|nuclear AhR complex|6S-nuclear aryl hydrocarbon (Ah) receptor ligand-activated complex													cellular_component											owl:Class	
GO:0003090	biolink:NamedThing	positive regulation of the force of heart contraction by neuronal epinephrine-norepinephrine	Any process that increases the force with which the cardiac muscles of the heart pump blood through the circulatory system as a result of the presence of epinephrine or norepinephrine released from the nerve endings.	tmpzr1t_l9r_go_relaxed.owl	increased force of heart contraction by neuronal epinephrine-norepinephrine|increased force of heart contraction by epinephrine-norepinephrine released from the nerve endings|increased force of heart contraction by neuronal adrenaline-noradrenaline|positive regulation of heart contraction by epinephrine-norepinephrine|positive regulation of heart contraction by adrenaline-noradrenaline													biological_process											owl:Class	
GO:0097116	biolink:NamedThing	gephyrin clustering involved in postsynaptic density assembly	The clustering process in which gephyrin molecules are localized to distinct domains in the postsynaptic density as part of postsynaptic density assembly. Gephyrin is a component of the postsynaptic protein network of inhibitory synapses.	tmpzr1t_l9r_go_relaxed.owl	Geph clustering							pr	2011-07-31T05:42:29Z					biological_process											owl:Class	
GO:0075331	biolink:NamedThing	negative regulation of arbuscule formation for nutrient acquisition from host	Any process that stops, prevents, or reduces the frequency, rate or extent of symbiont arbuscule formation for nutrient acquisition from host. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl						Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products from the symbiont involved in this process.								biological_process											owl:Class	
GO:0005876	biolink:NamedThing	spindle microtubule	Any microtubule that is part of a mitotic or meiotic spindle; anchored at one spindle pole.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0010693	biolink:NamedThing	negative regulation of alkaline phosphatase activity	Any process that decreases the frequency, rate or extent of alkaline phosphatase activity, the catalysis of the reaction: an orthophosphoric monoester + H2O = an alcohol + phosphate, with an alkaline pH optimum.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0103035	biolink:NamedThing	NAD(P)H:methyl-1,4-benzoquinone oxidoreductase activity	Catalysis of the reaction: 3 H+ + methyl-1,4-benzoquinone + NADPH = methyl-1,4-benzoquinol + NADP.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN0-5387									molecular_function											owl:Class	
GO:1901347	biolink:NamedThing	negative regulation of secondary cell wall biogenesis	Any process that stops, prevents or reduces the frequency, rate or extent of secondary cell wall biogenesis.	tmpzr1t_l9r_go_relaxed.owl	downregulation of secondary cell wall biogenesis|inhibition of secondary cell wall biogenesis|inhibition of plant-type secondary cell wall biogenesis|negative regulation of plant-type secondary cell wall biogenesis|down regulation of secondary cell wall formation|downregulation of secondary cell wall synthesis|down regulation of cellulose and pectin-containing secondary cell wall biogenesis|inhibition of secondary cell wall anabolism|downregulation of cellulose and pectin-containing secondary cell wall biogenesis|downregulation of secondary cell wall formation|downregulation of secondary cell wall biosynthetic process|down-regulation of plant-type secondary cell wall biogenesis|inhibition of secondary cell wall synthesis|down-regulation of secondary cell wall biosynthetic process|inhibition of secondary cell wall biosynthetic process|negative regulation of secondary cell wall biosynthetic process|downregulation of secondary cell wall anabolism|down regulation of plant-type secondary cell wall biogenesis|down regulation of secondary cell wall synthesis|negative regulation of secondary cell wall formation|negative regulation of cellulose and pectin-containing secondary cell wall biogenesis|negative regulation of secondary cell wall anabolism|negative regulation of secondary cell wall synthesis|down-regulation of secondary cell wall formation|down regulation of secondary cell wall biosynthetic process|down-regulation of secondary cell wall synthesis|down regulation of secondary cell wall anabolism|inhibition of cellulose and pectin-containing secondary cell wall biogenesis|down-regulation of secondary cell wall biogenesis|down regulation of secondary cell wall biogenesis|down-regulation of secondary cell wall anabolism|inhibition of secondary cell wall formation|downregulation of plant-type secondary cell wall biogenesis|down-regulation of cellulose and pectin-containing secondary cell wall biogenesis							tb	2012-09-07T17:58:05Z					biological_process											owl:Class	
GO:0033251	biolink:NamedThing	cephalosporinase activity	Catalysis of the reaction: a cephalosporin + H2O = a substituted beta-amino acid derivative of the cephalosporin.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:BETA-LACTAMASE-RXN									molecular_function											owl:Class	
GO:0061856	biolink:NamedThing	Golgi calcium ion transmembrane transport	A process in which a calcium ion is transported from one side of a Golgi membrane to the other by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl								dph	2017-03-14T16:08:23Z					biological_process											owl:Class	
GO:0032472	biolink:NamedThing	Golgi calcium ion transport	The directed movement of calcium ions (Ca2+) into, out of or within the Golgi apparatus.	tmpzr1t_l9r_go_relaxed.owl	Golgi calcium transport													biological_process											owl:Class	
GO:0071028	biolink:NamedThing	nuclear mRNA surveillance	The set of processes involved in identifying and degrading defective or aberrant mRNAs within the nucleus.	tmpzr1t_l9r_go_relaxed.owl	nuclear mRNA quality control|nuclear aberrant mRNA catabolic process							krc	2009-07-28T04:14:29Z					biological_process											owl:Class	
GO:0071027	biolink:NamedThing	nuclear RNA surveillance	The set of processes involved in identifying and degrading defective or aberrant RNAs within the nucleus.	tmpzr1t_l9r_go_relaxed.owl	nuclear aberrant RNA catabolic process|nuclear RNA quality control							krc	2009-07-28T03:45:02Z					biological_process											owl:Class	
GO:0006873	biolink:NamedThing	cellular ion homeostasis	Any process involved in the maintenance of an internal steady state of ions at the level of a cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1903061	biolink:NamedThing	positive regulation of protein lipidation	Any process that activates or increases the frequency, rate or extent of protein lipidation.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of lipid:protein modification|up-regulation of protein amino acid lipidation|activation of protein lipidation|upregulation of protein amino acid lipidation|activation of lipid:protein modification|up regulation of lipid:protein modification|up-regulation of protein lipidation|up regulation of protein amino acid lipidation|upregulation of protein lipidation|upregulation of lipid:protein modification|activation of protein amino acid lipidation|up regulation of protein lipidation|positive regulation of lipid:protein modification|positive regulation of protein amino acid lipidation							rph	2014-05-28T13:21:31Z					biological_process											owl:Class	
GO:0008974	biolink:NamedThing	phosphoribulokinase activity	Catalysis of the reaction: D-ribulose 5-phosphate + ATP = D-ribulose 1,5-bisphosphate + ADP + 2 H(+).	tmpzr1t_l9r_go_relaxed.owl	ribulose phosphate kinase activity|PKK|PRuK|phosphopentokinase activity|ribulose-5-phosphate kinase activity|5-phosphoribulose kinase activity|PRK|ATP:D-ribulose-5-phosphate 1-phosphotransferase activity|phosphoribulokinase (phosphorylating)				RHEA:19365|EC:2.7.1.19|KEGG_REACTION:R01523|MetaCyc:PHOSPHORIBULOKINASE-RXN									molecular_function											owl:Class	
GO:0031437	biolink:NamedThing	regulation of mRNA cleavage	Any process that modulates the frequency, rate or extent of mRNA cleavage, any process in which a pre-mRNA or mRNA molecule is cleaved at specific sites or in a regulated manner.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1990676	biolink:NamedThing	Golgi trans cisterna membrane	The lipid bilayer surrounding any of the thin, flattened compartments that form the trans portion of the Golgi complex.	tmpzr1t_l9r_go_relaxed.owl	trans-Golgi cisterna membrane							bhm	2015-03-02T11:53:35Z					cellular_component											owl:Class	
GO:0032580	biolink:NamedThing	Golgi cisterna membrane	The lipid bilayer surrounding any of the thin, flattened compartments that form the central portion of the Golgi complex.	tmpzr1t_l9r_go_relaxed.owl	Golgi stack membrane													cellular_component											owl:Class	
GO:0033774	biolink:NamedThing	basal labyrinth	A region in the lower half of some cells formed from extensive infoldings of the basal plasma membrane; includes cytoplasm adjacent to the infolded membrane.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0019353	biolink:NamedThing	protoporphyrinogen IX biosynthetic process from glutamate	The chemical reactions and pathways resulting in the formation of protoporphyrinogen IX from other compounds, including glutamate.	tmpzr1t_l9r_go_relaxed.owl	protoporphyrinogen IX synthesis from glutamate|protoporphyrinogen IX formation from glutamate|protoporphyrinogen IX anabolism from glutamate													biological_process											owl:Class	
GO:0015434	biolink:NamedThing	ABC-type cadmium transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Cd (cytosol) = ADP + phosphate + Cd (vacuole).	tmpzr1t_l9r_go_relaxed.owl	cadmium ABC transporter|ATP-dependent cadmium transmembrane transporter activity|cadmium-transporting ATPase activity|ATPase-coupled cadmium transmembrane transporter activity				EC:7.2.2.2|MetaCyc:3.6.3.46-RXN									molecular_function											owl:Class	
GO:0015086	biolink:NamedThing	cadmium ion transmembrane transporter activity	Enables the transfer of cadmium (Cd) ions from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	zinc, cadmium uptake permease activity|zinc, cadmium, cobalt, nickel, lead-efflux ATPase activity													molecular_function											owl:Class	
GO:0036120	biolink:NamedThing	cellular response to platelet-derived growth factor stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a platelet-derived growth factor stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to PDGF stimulus							bf	2012-02-20T02:49:02Z					biological_process											owl:Class	
GO:0052151	biolink:NamedThing	positive regulation by symbiont of host apoptotic process	Any process in which an organism activates, maintains or increases the frequency, rate or extent of programmed cell death in the host, where programmed cell death proceeds by apoptosis. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	upregulation by symbiont of host apoptosis|stimulation by symbiont of host apoptosis|up-regulation by symbiont of host apoptosis|up regulation by organism of host apoptotic programmed cell death|up-regulation by organism of host apoptotic programmed cell death|upregulation by organism of host apoptotic programmed cell death|up regulation by symbiont of host apoptosis|positive regulation by organism of host apoptotic programmed cell death|activation by symbiont of host apoptosis|activation by organism of host apoptotic programmed cell death|induction by organism of host apoptotic programmed cell death|induction by symbiont of host apoptosis|positive regulation by symbiont of host apoptosis|activation by organism of host apoptosis					Note that term is to be used to annotate gene products in the symbiont. To annotate host gene products, consider the biological process term 'positive regulation of apoptosis ; GO:0043065'.						GO:0033669|GO:0052030		biological_process											owl:Class	
GO:0007447	biolink:NamedThing	imaginal disc pattern formation	The regionalization process that results in defined areas of the imaginal disc that will undergo specific cell differentaiton. Imaginal discs are epithelial infoldings in the larvae of holometabolous insects that develop into adult appendages (legs, antennae, wings, etc.) during metamorphosis from larval to adult form.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0044774	biolink:NamedThing	mitotic DNA integrity checkpoint signaling	A signaling process that controls cell cycle progression in response to changes in DNA structure by monitoring the integrity of the DNA during mitosis. The DNA integrity checkpoint begins with detection of DNA damage, defects in DNA structure or DNA replication, and ends with signal transduction.	tmpzr1t_l9r_go_relaxed.owl	intracellular signal transduction involved in topo II checkpoint|signal transduction via intracellular signaling cascade involved in mitotic cell cycle G2/M transition decatenation checkpoint|intracellular signaling pathway involved in topo II checkpoint|intracellular signaling pathway involved in topoisomerase II checkpoint|intracellular signal transduction involved in mitotic cell cycle G2/M transition decatenation checkpoint|signal transduction involved in mitotic DNA integrity checkpoint|mitotic cell cycle G2/M transition decatenation checkpoint|mitotic DNA integrity checkpoint|intracellular signal transduction pathway involved in mitotic DNA integrity checkpoint|signal transduction via intracellular signaling cascade involved in topo II checkpoint|intracellular signal transduction pathway involved in topo II checkpoint|intracellular signaling cascade involved in mitotic DNA integrity checkpoint|intracellular signal transduction pathway involved in topoisomerase II checkpoint|intracellular signaling chain involved in mitotic DNA integrity checkpoint|intracellular signaling pathway involved in mitotic DNA integrity checkpoint|intracellular signaling cascade involved in topo II checkpoint|intracellular signaling pathway involved in mitotic cell cycle G2/M transition decatenation checkpoint|intracellular signal transduction pathway involved in mitotic cell cycle G2/M transition decatenation checkpoint|intracellular signaling cascade involved in mitotic cell cycle G2/M transition decatenation checkpoint|intracellular signaling chain involved in mitotic cell cycle G2/M transition decatenation checkpoint							jl	2013-02-28T16:07:26Z			GO:1902403|GO:0070683		biological_process											owl:Class	
GO:0031849	biolink:NamedThing	olfactory receptor binding	Binding to an olfactory receptor.	tmpzr1t_l9r_go_relaxed.owl	olfactory receptor ligand													molecular_function											owl:Class	
GO:0015408	biolink:NamedThing	ABC-type ferric iron transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Fe3+(out) = ADP + phosphate + Fe3+(in).	tmpzr1t_l9r_go_relaxed.owl	ATPase-coupled ferric iron transmembrane transporter activity|ferric-transporting ATPase activity|ferric transporting ATPase activity|Fe3+-transporting ATPase activity|ferric ABC transporter|ABC-type Fe3+ transporter				MetaCyc:3.6.3.30-RXN|RHEA:12332|EC:7.2.2.7									molecular_function											owl:Class	
GO:0043030	biolink:NamedThing	regulation of macrophage activation	Any process that modulates the frequency or rate of macrophage activation.	tmpzr1t_l9r_go_relaxed.owl	regulation of macrophage polarization													biological_process											owl:Class	
GO:0033893	biolink:NamedThing	ribonuclease IV activity	Catalysis of the endonucleolytic cleavage of poly(A) to fragments terminated by 3'-hydroxy and 5'-phosphate groups.	tmpzr1t_l9r_go_relaxed.owl	endoribonuclease IV activity				MetaCyc:3.1.26.6-RXN|EC:3.1.26.6									molecular_function											owl:Class	
GO:0034073	biolink:NamedThing	tetrahymanol cyclase activity	Catalysis of the reaction: squalene = tetrahymanol.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:2000620	biolink:NamedThing	positive regulation of histone H4-K16 acetylation	Any process that activates or increases the frequency, rate or extent of histone H4-K16 acetylation.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of histone H4 acetylation at K16							vk	2011-04-18T03:19:30Z					biological_process											owl:Class	
GO:2000618	biolink:NamedThing	regulation of histone H4-K16 acetylation	Any process that modulates the frequency, rate or extent of histone H4-K16 acetylation.	tmpzr1t_l9r_go_relaxed.owl	regulation of histone H4 acetylation at K16							vk	2011-04-18T03:19:23Z					biological_process											owl:Class	
GO:0061442	biolink:NamedThing	cardiac muscle cell fate determination	The process involved in cardiac muscle cell fate commitment. Once determination has taken place, a cell becomes committed to differentiate down a particular pathway regardless of its environment.	tmpzr1t_l9r_go_relaxed.owl								dph	2012-03-13T08:59:57Z					biological_process											owl:Class	
GO:0060913	biolink:NamedThing	cardiac cell fate determination	The process involved in cardiac cell fate commitment. Once determination has taken place, a cell becomes committed to differentiate down a particular pathway regardless of its environment.	tmpzr1t_l9r_go_relaxed.owl	cardiocyte cell fate determination							dph	2009-09-17T08:55:29Z					biological_process											owl:Class	
GO:1901378	biolink:NamedThing	organic heteropentacyclic compound biosynthetic process	The chemical reactions and pathways resulting in the formation of organic heteropentacyclic compound.	tmpzr1t_l9r_go_relaxed.owl	organic heteropentacyclic compound biosynthesis|organic heteropentacyclic compound formation|organic heteropentacyclic compound synthesis|organic heteropentacyclic compound anabolism							bf	2012-09-28T12:52:09Z					biological_process											owl:Class	
GO:0008870	biolink:NamedThing	galactoside O-acetyltransferase activity	Catalysis of the reaction: acetyl-CoA + a beta-D-galactoside = CoA + a 6-acetyl-beta-D-galactoside.	tmpzr1t_l9r_go_relaxed.owl	thiogalactoside acetyltransferase activity|acetyl-CoA:beta-D-galactoside 6-acetyltransferase activity|galactoside acetyltransferase activity|thiogalactoside transacetylase activity				RHEA:15713|EC:2.3.1.18|MetaCyc:GALACTOACETYLTRAN-RXN									molecular_function											owl:Class	
GO:0072070	biolink:NamedThing	loop of Henle development	The process whose specific outcome is the progression of the loop of Henle over time, from its formation to the mature structure. The loop of Henle is a nephron tubule that connects the proximal convoluted tubule to the distal convoluted tubule.	tmpzr1t_l9r_go_relaxed.owl	intermediate tubule development							mah	2010-01-25T04:20:27Z			GO:0072018		biological_process											owl:Class	
GO:0043059	biolink:NamedThing	regulation of forward locomotion	Any process that modulates the speed, mechanical force, or rhythm of the anterior movement of an organism.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0050570	biolink:NamedThing	4-hydroxythreonine-4-phosphate dehydrogenase activity	Catalysis of the reaction: 4-(phosphonooxy)-threonine + NAD+ = 2-amino-3-oxo-4-phosphonooxybutyrate + NADH + H+.	tmpzr1t_l9r_go_relaxed.owl	NAD(+)-dependent threonine 4-phosphate dehydrogenase activity|NAD+-dependent threonine 4-phosphate dehydrogenase activity|4-(phosphonooxy)-L-threonine:NAD+ oxidoreductase activity|PdxA|L-threonine 4-phosphate dehydrogenase activity|4-(phosphohydroxy)-L-threonine dehydrogenase activity				EC:1.1.1.262|MetaCyc:1.1.1.262-RXN|RHEA:32275									molecular_function											owl:Class	
GO:0030199	biolink:NamedThing	collagen fibril organization	Any process that determines the size and arrangement of collagen fibrils within an extracellular matrix.	tmpzr1t_l9r_go_relaxed.owl	collagen fibril organisation|fibrillar collagen organization													biological_process											owl:Class	
GO:0042605	biolink:NamedThing	peptide antigen binding	Binding to an antigen peptide.	tmpzr1t_l9r_go_relaxed.owl	exogenous peptide antigen binding|endogenous peptide antigen binding					Note that this term can be used to describe the binding of a peptide to an MHC molecule.						GO:0042606|GO:0042607		molecular_function											owl:Class	
GO:0051156	biolink:NamedThing	glucose 6-phosphate metabolic process	The chemical reactions and pathways involving glucose 6-phosphate, a monophosphorylated derivative of glucose with the phosphate group attached to C-6.	tmpzr1t_l9r_go_relaxed.owl	glucose 6-phosphate metabolism|glucose 6-phosphate utilization											GO:0006010		biological_process											owl:Class	
GO:0102737	biolink:NamedThing	p-coumaroyltriacetic acid synthase activity	Catalysis of the reaction: 2 H+ + 4-coumaryl-CoA + H2O + 3 malonyl-CoA <=> 4 coenzyme A + 3 carbon dioxide + p-coumaroyltriacetate.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-7577									molecular_function											owl:Class	
GO:0035223	biolink:NamedThing	leg disc pattern formation	The process that gives rise to the patterns of cell differentiation in the leg imaginal disc.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0032385	biolink:NamedThing	positive regulation of intracellular cholesterol transport	Any process that activates or increases the frequency, rate or extent of the directed movement of cholesterol within cells.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of intracellular cholesterol transport|up regulation of intracellular cholesterol transport|stimulation of intracellular cholesterol transport|activation of intracellular cholesterol transport|upregulation of intracellular cholesterol transport													biological_process											owl:Class	
GO:0075274	biolink:NamedThing	negative regulation of zygosporangium development	Any process that stops, prevents, or reduces the frequency, rate or extent of zygosporangium development, a process in which a fruiting body called zygosporangium is formed.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0042754	biolink:NamedThing	negative regulation of circadian rhythm	Any process that stops, prevents, or reduces the frequency, rate or extent of a circadian rhythm behavior.	tmpzr1t_l9r_go_relaxed.owl	inhibition of circadian rhythm|down-regulation of circadian rhythm|down regulation of circadian rhythm|downregulation of circadian rhythm													biological_process											owl:Class	
GO:1902558	biolink:NamedThing	5'-adenylyl sulfate transmembrane transport	The process in which 5'-adenylyl sulfate is transported across a membrane.	tmpzr1t_l9r_go_relaxed.owl	adenosine 5'-phosphosulfate transmembrane transport							mcc	2013-12-09T23:16:01Z					biological_process											owl:Class	
GO:1990941	biolink:NamedThing	mitotic spindle kinetochore microtubule	Any of the mitotic spindle microtubules that attach to the kinetochores of chromosomes by their plus ends, and maneuver the chromosomes during mitotic chromosome segregation.	tmpzr1t_l9r_go_relaxed.owl								vw	2016-04-06T13:31:38Z					cellular_component											owl:Class	
GO:1990498	biolink:NamedThing	mitotic spindle microtubule	Any microtubule that is part of a mitotic spindle; anchored at one spindle pole.	tmpzr1t_l9r_go_relaxed.owl								vw	2014-09-26T13:34:40Z					cellular_component											owl:Class	
GO:1902112	biolink:NamedThing	cellular response to diethyl maleate	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diethyl maleate stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2013-05-08T16:00:40Z					biological_process											owl:Class	
GO:1904911	biolink:NamedThing	negative regulation of establishment of RNA localization to telomere	Any process that stops, prevents or reduces the frequency, rate or extent of establishment of RNA localization to telomere.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of establishment of RNA localization to telomere|down-regulation of establishment of RNA localisation to telomere|inhibition of establishment of RNA localisation to telomere|downregulation of establishment of RNA localisation to telomere|downregulation of establishment of RNA localization to telomere|down regulation of establishment of RNA localisation to telomere|negative regulation of establishment of RNA localisation to telomere|inhibition of establishment of RNA localization to telomere|down regulation of establishment of RNA localization to telomere							rph	2016-01-19T10:34:28Z					biological_process											owl:Class	
GO:1905711	biolink:NamedThing	response to phosphatidylethanolamine	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a phosphatidylethanolamine stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to PtdEtn|response to phosphatidylethanolamines|response to phosphatidyl(amino)ethanols|response to PE							sl	2016-11-21T19:55:32Z					biological_process											owl:Class	
GO:0022834	biolink:NamedThing	ligand-gated channel activity	Enables the transmembrane transfer of a solute by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1901354	biolink:NamedThing	response to L-canavanine	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-canavanine stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2012-09-13T13:11:17Z					biological_process											owl:Class	
GO:0004436	biolink:NamedThing	phosphatidylinositol diacylglycerol-lyase activity	Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol = D-myo-inositol 1,2-cyclic phosphate + diacylglycerol.	tmpzr1t_l9r_go_relaxed.owl	1-phosphatidyl-D-myo-inositol inositolphosphohydrolase (cyclic-phosphate-forming)|1-phosphatidyl-1D-myo-inositol diacyl-sn-glycerol-lyase (1D-myo-inositol-1,2-cyclic-phosphate-forming)|1-phosphatidyl-1D-myo-inositol diacylglycerol-lyase (1,2-cyclic-phosphate-forming)|1-phosphatidylinositol phosphodiesterase activity|monophosphatidylinositol phosphodiesterase activity				EC:4.6.1.13|MetaCyc:3.1.4.10-RXN|RHEA:17093	Note that this function was formerly EC:3.1.4.10.								molecular_function											owl:Class	
GO:0051096	biolink:NamedThing	positive regulation of helicase activity	Any process that activates or increases the activity of a helicase.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of helicase activity|up regulation of helicase activity|stimulation of helicase activity|upregulation of helicase activity|activation of helicase activity													biological_process											owl:Class	
GO:0035002	biolink:NamedThing	liquid clearance, open tracheal system	The clearance of liquid from the epithelial tubes of an open tracheal system, shortly before the emergence of the larva, to generate an air-filled tubule system.	tmpzr1t_l9r_go_relaxed.owl	tracheal liquid clearance													biological_process											owl:Class	
GO:0042045	biolink:NamedThing	epithelial fluid transport	The directed movement of fluid across epithelia.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0035543	biolink:NamedThing	positive regulation of SNARE complex assembly	Any process that increases the frequency, rate or extent of assembly of the SNARE complex. The SNARE complex is a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers.	tmpzr1t_l9r_go_relaxed.owl								bf	2010-05-10T01:50:02Z					biological_process											owl:Class	
GO:0036509	biolink:NamedThing	trimming of terminal mannose on B branch	The removal of an alpha-1,2-linked mannose from the B-chain of a glycoprotein oligosaccharide in the endoplasmic reticulum.	tmpzr1t_l9r_go_relaxed.owl	conversion of M9 to M8B|conversion of (Man)9(GlcNAc)2 to (Man)8B(GlcNAc)2|glycoprotein mannose trimming on B branch				KEGG_REACTION:R06722	Consider also annotating to 'mannosyl-oligosaccharide 1,2-alpha-mannosidase activity ; GO:0004571'.		bf	2015-06-11T14:02:44Z					biological_process											owl:Class	
GO:0042627	biolink:NamedThing	chylomicron	A large lipoprotein particle (diameter 75-1200 nm) composed of a central core of triglycerides and cholesterol surrounded by a protein-phospholipid coating. The proteins include one molecule of apolipoprotein B-48 and may include a variety of apolipoproteins, including APOAs, APOCs and APOE. Chylomicrons are found in blood or lymph and carry lipids from the intestines into other body tissues.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Chylomicron									cellular_component											owl:Class	
GO:1905288	biolink:NamedThing	vascular associated smooth muscle cell apoptotic process	Any apoptotic process in a vascular associated smooth muscle cell.	tmpzr1t_l9r_go_relaxed.owl	vascular smooth muscle cell apoptotic process|VSMC apoptosis|VSMC apoptotic process|vascular associated smooth muscle cell apoptosis|vascular smooth muscle cell apoptosis							rph	2016-06-23T13:24:20Z					biological_process											owl:Class	
GO:0034390	biolink:NamedThing	smooth muscle cell apoptotic process	Any apoptotic process in a smooth muscle cell. Smooth muscle consists of non-striated, elongated, spindle-shaped cell found lining the digestive tract, uterus, and blood vessels.	tmpzr1t_l9r_go_relaxed.owl	SMC apoptosis|smooth muscle cell programmed cell death by apoptosis|programmed cell death, smooth muscle cells|smooth muscle cell apoptosis|apoptosis of smooth muscle cells|programmed cell death of smooth muscle cells by apoptosis													biological_process											owl:Class	
GO:0071123	biolink:NamedThing	alpha9-beta1 integrin-VEGF-C complex	A protein complex that consists of an alpha9-beta1 integrin complex bound to vascular endothelial growth factor C.	tmpzr1t_l9r_go_relaxed.owl	ITGA9-ITGB1-VEGFC complex							mah	2009-11-13T02:22:27Z					cellular_component											owl:Class	
GO:0048440	biolink:NamedThing	carpel development	The process whose specific outcome is the progression of the carpel over time, from its formation to the mature structure. A carpel is an organ (generally believed to be a modified foliar unit) at the centre of a flower, bearing one or more ovules and having its margins fused together or with other carpels to enclose the ovule in an ovary, and consisting also of a stigma and usually a style.	tmpzr1t_l9r_go_relaxed.owl												GO:0048429		biological_process											owl:Class	
GO:0048827	biolink:NamedThing	phyllome development	The process whose specific outcome is the progression of a phyllome over time, from its formation to the mature structure. A phyllome is a collective term for all the different types of leaves appearing on plants.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0031906	biolink:NamedThing	late endosome lumen	The volume enclosed by the membrane of a late endosome.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0140708	biolink:NamedThing	CAT tailing	The C-terminal elongation of 60S-anchored stalled nascent polypeptide chains with untemplated alanine and threonine tails (CAT tails). CAT tails participate in the recognition of stalled nascent chains by the ribosome quality control sytem.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/21987						pg	2021-09-03T13:16:20Z					biological_process											owl:Class	
GO:0030835	biolink:NamedThing	negative regulation of actin filament depolymerization	Any process that stops, prevents, or reduces the frequency, rate or extent of actin depolymerization.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of actin polymerization and/or depolymerization|negative regulation of actin depolymerization|down-regulation of actin filament depolymerization|downregulation of actin filament depolymerization|down regulation of actin filament depolymerization|inhibition of actin filament depolymerization|actin filament stabilization					Note that this term was split from 'negative regulation of actin polymerization and/or depolymerization ; GO:0045757' (sibling term 'negative regulation of actin polymerization ; GO:0030837').						GO:0030044		biological_process											owl:Class	
GO:0035330	biolink:NamedThing	regulation of hippo signaling	Any process that modulates the frequency, rate or extent of hippo signaling.	tmpzr1t_l9r_go_relaxed.owl	regulation of hippo signaling pathway|regulation of hippo signalling cascade|regulation of hippo signaling cascade							bf	2010-02-26T10:53:05Z					biological_process											owl:Class	
GO:0072188	biolink:NamedThing	metanephric cap specification	The process in which the metanephric cap acquires its identity.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-03-01T01:35:25Z					biological_process											owl:Class	
GO:0018964	biolink:NamedThing	propylene metabolic process	The chemical reactions and pathways involving propylene, an alkene produced by catalytic or thermal cracking of hydrocarbons or as a by-product of petroleum refining. It is used mainly in the preparation of alkylates for gasoline and in the production of polypropylene, acrylonitrile, propylene oxide and a number of other industrial chemicals.	tmpzr1t_l9r_go_relaxed.owl	propylene metabolism				UM-BBD_pathwayID:pro									biological_process											owl:Class	
GO:0019597	biolink:NamedThing	(R)-mandelate catabolic process to benzoate	The chemical reactions and pathways resulting in the breakdown of (R)-mandelate into other compounds, including benzoate.	tmpzr1t_l9r_go_relaxed.owl	(R)-mandelate breakdown to benzoate|(R)-mandelate degradation to benzoate													biological_process											owl:Class	
GO:0022900	biolink:NamedThing	electron transport chain	A process in which a series of electron carriers operate together to transfer electrons from donors to any of several different terminal electron acceptors.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/21455			Wikipedia:Electron_transport_chain									biological_process											owl:Class	
GO:0043608	biolink:NamedThing	formamide catabolic process	The chemical reactions and pathways resulting in the breakdown of formamide, the simplest amide, HCONH2, derived from formic acid.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0006146	biolink:NamedThing	adenine catabolic process	The chemical reactions and pathways resulting in the breakdown of adenine, 6-aminopurine, one of the 5 main bases found in nucleic acids and a component of numerous important derivatives of its corresponding ribonucleoside, adenosine.	tmpzr1t_l9r_go_relaxed.owl	adenine degradation|adenine breakdown|adenine catabolism													biological_process											owl:Class	
GO:0120287	biolink:NamedThing	regulation of aspartic endopeptidase activity, intramembrane cleaving	Any process that modulates the frequency, rate or extent of intramembrane cleaving aspartic-type endopeptidase activity.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/20341						krc	2020-11-19T22:06:06Z					biological_process											owl:Class	
GO:0034637	biolink:NamedThing	cellular carbohydrate biosynthetic process	The chemical reactions and pathways resulting in the formation of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y, carried out by individual cells.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0006267	biolink:NamedThing	pre-replicative complex assembly involved in nuclear cell cycle DNA replication	The aggregation, arrangement and bonding together of a set of components to form the nuclear pre-replicative complex, a protein-DNA complex that forms at the eukaryotic DNA replication origin and is required for replication initiation.	tmpzr1t_l9r_go_relaxed.owl	pre-replicative complex formation|nuclear pre-replicative complex assembly|pre-replicative complex assembly|pre-RC complex assembly													biological_process											owl:Class	
GO:0004525	biolink:NamedThing	ribonuclease III activity	Catalysis of the endonucleolytic cleavage of RNA with 5'-phosphomonoesters and 3'-OH termini; makes two staggered cuts in both strands of dsRNA, leaving a 3' overhang of 2 nt.	tmpzr1t_l9r_go_relaxed.owl	pre-mRNA 3'-end processing endonuclease|ribonuclease 3 activity|RNase III activity				Reactome:R-HSA-203862|Reactome:R-HSA-426464|Reactome:R-HSA-203893|EC:3.1.26.3|MetaCyc:3.1.26.3-RXN									molecular_function											owl:Class	
GO:0008836	biolink:NamedThing	diaminopimelate decarboxylase activity	Catalysis of the reaction: meso-2,6-diaminopimelate + H(+) = L-lysine + CO(2).	tmpzr1t_l9r_go_relaxed.owl	meso-diaminopimelate decarboxylase activity|meso-2,6-diaminoheptanedioate carboxy-lyase activity|meso-2,6-diaminoheptanedioate carboxy-lyase (L-lysine-forming)|diaminopimelic acid decarboxylase activity|DAP-decarboxylase activity|DAP decarboxylase activity				KEGG_REACTION:R00451|RHEA:15101|EC:4.1.1.20|MetaCyc:DIAMINOPIMDECARB-RXN									molecular_function											owl:Class	
GO:0034936	biolink:NamedThing	4,6-dichloro-3-methylcatechol 1,2-dioxygenase activity	Catalysis of the reaction: 4,6-dichloro-3-methylcatechol + O2 = 3,5-dichloro-3-methyl-cis,cis-muconate + 2 H+.	tmpzr1t_l9r_go_relaxed.owl					EC:1.13.11.-|UM-BBD_reactionID:r0959									molecular_function											owl:Class	
GO:1903305	biolink:NamedThing	regulation of regulated secretory pathway	Any process that modulates the frequency, rate or extent of regulated secretory pathway.	tmpzr1t_l9r_go_relaxed.owl						An example of this is protein domain-specific expression of Synaptotagmin 1 in rat (P21707) in PMID:12526776 inferred from mutant phenotype.		pad	2014-08-18T10:04:53Z					biological_process											owl:Class	
GO:0046196	biolink:NamedThing	4-nitrophenol catabolic process	The chemical reactions and pathways resulting in the breakdown of 4-nitrophenol, a nitroaromatic compound which is used in the production of dyes, leather treatment agents, fungicides and as an intermediate in the production of the insecticide parathion.	tmpzr1t_l9r_go_relaxed.owl	4-nitrophenol degradation|4-nitrophenol breakdown|4-nitrophenol catabolism													biological_process											owl:Class	
GO:1904841	biolink:NamedThing	TORC2 complex binding	Binding to a TORC2 complex.	tmpzr1t_l9r_go_relaxed.owl	TORC 2 complex binding|TORC2 binding|TOR complex 2 binding|rapamycin and nutrient-insensitive TOR complex binding|mTORC2 binding					Binding to a TORC2 complex, a protein complex that mediates the phosphorylation of protein kinase B		pf	2015-12-07T16:59:44Z					molecular_function											owl:Class	
GO:0071406	biolink:NamedThing	cellular response to methylmercury	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methylmercury stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to CH3-Hg+|cellular response to MeHg+							mah	2009-12-14T02:55:12Z					biological_process											owl:Class	
GO:0060183	biolink:NamedThing	apelin receptor signaling pathway	The series of molecular signals generated as a consequence of an apelin receptor binding to one of its physiological ligands.	tmpzr1t_l9r_go_relaxed.owl	apelin receptor signalling pathway													biological_process											owl:Class	
GO:0002914	biolink:NamedThing	regulation of central B cell anergy	Any process that modulates the frequency, rate, or extent of central B cell anergy.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1904246	biolink:NamedThing	negative regulation of polynucleotide adenylyltransferase activity	Any process that stops, prevents or reduces the frequency, rate or extent of polynucleotide adenylyltransferase activity.	tmpzr1t_l9r_go_relaxed.owl	inhibition of ATP:polynucleotide adenylyltransferase activity|negative regulation of NTP polymerase activity|inhibition of polyadenylic polymerase activity|downregulation of polyadenylic polymerase activity|down regulation of polynucleotide adenylyltransferase activity|down-regulation of ATP:polynucleotidylexotransferase activity|down-regulation of polyadenylate polymerase activity|down regulation of adenosine triphosphate:ribonucleic acid adenylyltransferase activity|down-regulation of poly(A) hydrolase activity|inhibition of polyadenylate synthetase activity|down regulation of poly(A) polymerase activity|negative regulation of ATP-polynucleotide adenylyltransferase activity|down-regulation of ATP:polynucleotide adenylyltransferase activity|negative regulation of poly(A) synthetase activity|inhibition of RNA adenylating enzyme activity|down regulation of polyadenylate synthetase activity|negative regulation of AMP polynucleotidylexotransferase activity|negative regulation of terminal riboadenylate transferase activity|down regulation of poly(A) synthetase activity|inhibition of poly-A polymerase activity|negative regulation of poly(A) hydrolase activity|down-regulation of RNA formation factors, PF1|downregulation of terminal riboadenylate transferase activity|down regulation of AMP polynucleotidylexotransferase activity|down regulation of ATP:polynucleotide adenylyltransferase activity|inhibition of adenosine triphosphate:ribonucleic acid adenylyltransferase activity|downregulation of AMP polynucleotidylexotransferase activity|negative regulation of polyadenylic polymerase activity|down-regulation of AMP polynucleotidylexotransferase activity|inhibition of AMP polynucleotidylexotransferase activity|down regulation of polyadenylate polymerase activity|downregulation of polyadenylate nucleotidyltransferase activity|inhibition of polynucleotide adenylyltransferase activity|downregulation of polyadenylic acid polymerase activity|down regulation of polyadenylic polymerase activity|negative regulation of poly-A polymerase activity|down-regulation of NTP polymerase activity|inhibition of poly(A) polymerase activity|downregulation of poly(A) synthetase activity|negative regulation of ATP:polynucleotidylexotransferase activity|downregulation of RNA adenylating enzyme activity|negative regulation of ATP:polynucleotide adenylyltransferase activity|inhibition of polyadenylic acid polymerase activity|inhibition of RNA formation factors, PF1|downregulation of polynucleotide adenylyltransferase activity|inhibition of polyadenylate polymerase activity|negative regulation of polyadenylic acid polymerase activity|down regulation of polyadenylic acid polymerase activity|inhibition of NTP polymerase activity|inhibition of ATP:polynucleotidylexotransferase activity|inhibition of terminal riboadenylate transferase activity|downregulation of RNA formation factors, PF1|inhibition of poly(A) hydrolase activity|down regulation of poly-A polymerase activity|downregulation of NTP polymerase activity|down-regulation of RNA adenylating enzyme activity|down-regulation of polyadenylic polymerase activity|down-regulation of poly(A) polymerase activity|negative regulation of polyadenylate synthetase activity|down regulation of ATP:polynucleotidylexotransferase activity|down-regulation of poly(A) synthetase activity|down-regulation of ATP-polynucleotide adenylyltransferase activity|inhibition of polyadenylate nucleotidyltransferase activity|down-regulation of terminal riboadenylate transferase activity|down regulation of RNA formation factors, PF1|negative regulation of poly(A) polymerase activity|negative regulation of RNA adenylating enzyme activity|downregulation of poly-A polymerase activity|down regulation of NTP polymerase activity|negative regulation of adenosine triphosphate:ribonucleic acid adenylyltransferase activity|down-regulation of polynucleotide adenylyltransferase activity|down-regulation of polyadenylic acid polymerase activity|down-regulation of poly-A polymerase activity|downregulation of ATP:polynucleotidylexotransferase activity|downregulation of polyadenylate polymerase activity|negative regulation of polyadenylate nucleotidyltransferase activity|down regulation of terminal riboadenylate transferase activity|negative regulation of RNA formation factors, PF1|downregulation of ATP:polynucleotide adenylyltransferase activity|down regulation of poly(A) hydrolase activity|inhibition of poly(A) synthetase activity|down regulation of ATP-polynucleotide adenylyltransferase activity|negative regulation of polyadenylate polymerase activity|downregulation of poly(A) hydrolase activity|downregulation of adenosine triphosphate:ribonucleic acid adenylyltransferase activity|down regulation of RNA adenylating enzyme activity|down-regulation of polyadenylate nucleotidyltransferase activity|inhibition of ATP-polynucleotide adenylyltransferase activity|downregulation of poly(A) polymerase activity|down-regulation of polyadenylate synthetase activity|downregulation of polyadenylate synthetase activity|down regulation of polyadenylate nucleotidyltransferase activity|down-regulation of adenosine triphosphate:ribonucleic acid adenylyltransferase activity|downregulation of ATP-polynucleotide adenylyltransferase activity							kmv	2015-05-19T14:47:26Z					biological_process											owl:Class	
GO:0047120	biolink:NamedThing	(3S,4R)-3,4-dihydroxycyclohexa-1,5-diene-1,4-dicarboxylate dehydrogenase activity	Catalysis of the reaction: (3S,4R)-3,4-dihydroxycyclohexa-1,5-diene-1,4-dicarboxylate + NAD(+) = 3,4-dihydroxybenzoate + CO(2) + NADH.	tmpzr1t_l9r_go_relaxed.owl	(1R,2S)-dihydroxy-3,5-cyclohexadiene-1,4-dicarboxylate dehydrogenase activity|terephthalate 1,2-cis-dihydrodiol dehydrogenase activity|dihydroxy-3,5-cyclohexadiene-1,4-dicarboxylate dehydrogenase activity|(3S,4R)-3,4-dihydroxycyclohexa-1,5-diene-1,4-dicarboxylate:NAD+ oxidoreductase activity|cis-4,5-dihydroxycyclohexa-1(6),2-diene-1,4-dicarboxylate:NAD+ oxidoreductase (decarboxylating)				RHEA:10744|UM-BBD_reactionID:r0151|MetaCyc:1.3.1.53-RXN|KEGG_REACTION:R01633|EC:1.3.1.53							GO:0018514		molecular_function											owl:Class	
GO:0050613	biolink:NamedThing	delta14-sterol reductase activity	Catalysis of the reaction: NADP+ + 4,4-dimethyl-5-alpha-cholesta-8,24-dien-3-beta-ol = NADPH + H+ + 4,4-dimethyl-5-alpha-cholesta-8,14,24-trien-3-beta-ol.	tmpzr1t_l9r_go_relaxed.owl	C-14 sterol reductase activity|sterol C-14 reductase activity|sterol C14-reductase activity|4,4-dimethyl-5alpha-cholesta-8,24-dien-3beta-ol:NADP+ delta14-oxidoreductase activity|D14-sterol reductase activity				RHEA:18561|Reactome:R-HSA-194698|Reactome:R-HSA-194674|MetaCyc:1.3.1.70-RXN|EC:1.3.1.70	Note that zymosterol is cholesta-8,24-dien-3-ol.						GO:0000251		molecular_function											owl:Class	
GO:0008746	biolink:NamedThing	NAD(P)+ transhydrogenase activity	Catalysis of the reaction: NADPH + H+ + NAD+ = NADP+ + NADH + H+.	tmpzr1t_l9r_go_relaxed.owl	NAD transhydrogenase|pyridine nucleotide transferase|NADPH-NAD transhydrogenase|NADPH:NAD+ transhydrogenase|nicotinamide adenine dinucleotide (phosphate) transhydrogenase|NADH-NADP-transhydrogenase|NADPH-NAD oxidoreductase|energy-linked transhydrogenase|H+-thase|NADH transhydrogenase				RHEA:11692|EC:1.6.1.1|KEGG_REACTION:R00112|Reactome:R-HSA-450971									molecular_function											owl:Class	
GO:0016652	biolink:NamedThing	oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces NAD+ or NADP.	tmpzr1t_l9r_go_relaxed.owl	oxidoreductase activity, acting on NAD or NADPH, NAD or NADP as acceptor				EC:1.6.1.-									molecular_function											owl:Class	
GO:1905327	biolink:NamedThing	tracheoesophageal septum formation	The process that gives rise to the tracheoesophageal septum. This process pertains to the initial formation of a structure from unspecified parts.	tmpzr1t_l9r_go_relaxed.owl	esophagotracheal septum formation|tracheoesophageal ridges formation							tb	2016-07-21T18:18:57Z					biological_process											owl:Class	
GO:1905572	biolink:NamedThing	ganglioside GM1 transport to membrane	The directed movement of ganglioside GM1 to membrane.	tmpzr1t_l9r_go_relaxed.owl								pga	2016-10-19T10:50:44Z					biological_process											owl:Class	
GO:0048692	biolink:NamedThing	negative regulation of axon extension involved in regeneration	Any process that stops, prevents, or reduces the frequency, rate or extent of axon extension involved in regeneration.	tmpzr1t_l9r_go_relaxed.owl	downregulation of axon extension involved in regeneration|inhibition of axon extension involved in regeneration|down-regulation of axon extension involved in regeneration|down regulation of axon extension involved in regeneration													biological_process											owl:Class	
GO:0071213	biolink:NamedThing	cellular response to 1-aminocyclopropane-1-carboxylic acid	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 1-aminocyclopropane-1-carboxylic acid stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-12-03T12:10:11Z					biological_process											owl:Class	
GO:0044620	biolink:NamedThing	ACP phosphopantetheine attachment site binding	Binding to the attachment site of the phosphopantetheine prosthetic group of an acyl carrier protein (ACP).	tmpzr1t_l9r_go_relaxed.owl								jl	2012-07-04T03:25:04Z					molecular_function											owl:Class	
GO:0086066	biolink:NamedThing	atrial cardiac muscle cell to AV node cell communication	The process that mediates interactions between an atrial cardiomyocyte and its surroundings that contributes to the process of the atrial cardiomyocyte communicating with an AV node cell in cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.	tmpzr1t_l9r_go_relaxed.owl	atrial cardiomyocyte to atrioventricular node cell communication|atrial cardiomyocyte to AV node cell communication							dph	2011-11-22T09:05:09Z					biological_process											owl:Class	
GO:0003743	biolink:NamedThing	translation initiation factor activity	Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-72722|Reactome:R-HSA-72697|Reactome:R-HSA-72621							GO:0003745|GO:0003744		molecular_function											owl:Class	
GO:0071507	biolink:NamedThing	pheromone response MAPK cascade	A MAPK cascade that is part of a pheromone response ending in conjugation with cellular fusion.	tmpzr1t_l9r_go_relaxed.owl	Fus3 signaling cascade|conjugation with cellular fusion, MAPKKK cascade|pheromone MAPK module|MAPKKK cascade involved in mating response|MAPKKK cascade involved in conjugation with cellular fusion|MAPK cascade involved in conjugation with cellular fusion|MAPK signaling in response to pheromone							mah	2010-01-05T01:43:47Z					biological_process											owl:Class	
GO:0006638	biolink:NamedThing	neutral lipid metabolic process	The chemical reactions and pathways involving neutral lipids, lipids only soluble in solvents of very low polarity.	tmpzr1t_l9r_go_relaxed.owl	neutral lipid metabolism													biological_process											owl:Class	
GO:0051267	biolink:NamedThing	CP2 mannose-ethanolamine phosphotransferase activity	Catalysis of the reaction: ethanolamine phosphate + Man-alpha-(1,2)-Man-alpha-(1,2)-Man-alpha-(1,6)-R = Man-alpha-(1,2)-Man-alpha-6-P-EtN-(1,2)-Man-alpha-(1,6)-R; R is Man-alpha(1,4)-GlcNH2-inositol-PO4-lipid. This reaction is the transfer of ethanolamine phosphate to C6 of second mannose in the GPI lipid precursor CP2.	tmpzr1t_l9r_go_relaxed.owl	CP2 EtN-P transferase activity|CP2 ethanolamine phosphate transferase activity|gpi7 activity|addition of ethanolamine phosphate to mannose of GPI precursor CP2|CP2 phosphoethanolamine transferase activity													molecular_function											owl:Class	
GO:0051377	biolink:NamedThing	mannose-ethanolamine phosphotransferase activity	Catalysis of the transfer of ethanolamine phosphate to a mannose residue in the GPI lipid precursor.	tmpzr1t_l9r_go_relaxed.owl	ethanolamine phosphate transferase activity|phosphoethanolamine transferase activity|addition of ethanolamine phosphate to mannose of GPI precursor|EtN-P transferase activity				Reactome:R-HSA-162798									molecular_function											owl:Class	
GO:0032017	biolink:NamedThing	positive regulation of Ran protein signal transduction	Any process that activates or increases the frequency, rate or extent of Ran protein signal transduction.	tmpzr1t_l9r_go_relaxed.owl	activation of Ran protein signal transduction|upregulation of Ran protein signal transduction|up-regulation of Ran protein signal transduction|up regulation of Ran protein signal transduction|stimulation of Ran protein signal transduction													biological_process											owl:Class	
GO:0043159	biolink:NamedThing	acrosomal matrix	A structural framework, or 'dense core' at the interior of an acrosome. May regulate the distribution of hydrolases within the acrosome and their release during the acrosome reaction.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0120281	biolink:NamedThing	autolysosome membrane	A lipid bilayer that surrounds an autolysosome, a single-membrane-bounded vesicle in which endogenous cellular material is degraded.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/20239						krc	2020-11-17T02:46:19Z					cellular_component											owl:Class	
GO:0000421	biolink:NamedThing	autophagosome membrane	The lipid bilayer surrounding an autophagosome, a double-membrane-bounded vesicle in which endogenous cellular material is sequestered.	tmpzr1t_l9r_go_relaxed.owl	autophagic vacuole membrane													cellular_component											owl:Class	
GO:1902038	biolink:NamedThing	positive regulation of hematopoietic stem cell differentiation	Any process that activates or increases the frequency, rate or extent of hematopoietic stem cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	upregulation of hemopoietic stem cell differentiation|positive regulation of hemopoietic stem cell differentiation|upregulation of haematopoietic stem cell differentiation|activation of haematopoietic stem cell differentiation|up regulation of hemopoietic stem cell differentiation|upregulation of haemopoietic stem cell differentiation|up-regulation of haematopoietic stem cell differentiation|up-regulation of hemopoietic stem cell differentiation|up-regulation of haemopoietic stem cell differentiation|up regulation of haemopoietic stem cell differentiation|up regulation of hematopoietic stem cell differentiation|positive regulation of haematopoietic stem cell differentiation|up-regulation of hematopoietic stem cell differentiation|activation of hemopoietic stem cell differentiation|activation of hematopoietic stem cell differentiation|activation of haemopoietic stem cell differentiation|up regulation of haematopoietic stem cell differentiation|positive regulation of haemopoietic stem cell differentiation|upregulation of hematopoietic stem cell differentiation							ss	2013-04-02T05:19:19Z					biological_process											owl:Class	
GO:1990776	biolink:NamedThing	response to angiotensin	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an angiotensin stimulus. Angiotensin is any of three physiologically active peptides (angiotensin II, III, or IV) processed from angiotensinogen.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-06-16T17:41:17Z					biological_process											owl:Class	
GO:0032224	biolink:NamedThing	positive regulation of synaptic transmission, cholinergic	Any process that activates, maintains or increases the frequency, rate or extent of cholinergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter acetylcholine.	tmpzr1t_l9r_go_relaxed.owl	activation of synaptic transmission, cholinergic|stimulation of synaptic transmission, cholinergic|up regulation of synaptic transmission, cholinergic|up-regulation of synaptic transmission, cholinergic|upregulation of synaptic transmission, cholinergic													biological_process											owl:Class	
GO:0000172	biolink:NamedThing	ribonuclease MRP complex	A ribonucleoprotein complex that contains an RNA molecule of the snoRNA family, and cleaves the rRNA precursor as part of rRNA transcript processing. It also has other roles: In S. cerevisiae it is involved in cell cycle-regulated degradation of daughter cell-specific mRNAs, while in mammalian cells it also enters the mitochondria and processes RNAs to create RNA primers for DNA replication.	tmpzr1t_l9r_go_relaxed.owl	RNase MRP complex|ribonuclease mitochondrial RNA processing complex													cellular_component											owl:Class	
GO:0042699	biolink:NamedThing	follicle-stimulating hormone signaling pathway	The series of molecular signals mediated by follicle-stimulating hormone.	tmpzr1t_l9r_go_relaxed.owl	follicle stimulating hormone signaling pathway|follicle-stimulating hormone signalling pathway|follicle stimulating hormone signalling pathway													biological_process											owl:Class	
GO:2001148	biolink:NamedThing	regulation of dipeptide transmembrane transport	Any process that modulates the frequency, rate or extent of dipeptide transmembrane transport.	tmpzr1t_l9r_go_relaxed.owl	regulation of dipeptide membrane transport							kmv	2011-10-21T04:34:20Z					biological_process											owl:Class	
GO:0004028	biolink:NamedThing	3-chloroallyl aldehyde dehydrogenase activity	Catalysis of the reaction: 3-chloroallyl aldehyde + H2O = 2 H+ + 2 e- + 3-chloroacrylic acid.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_enzymeID:e0432|Reactome:R-HSA-71260									molecular_function											owl:Class	
GO:1900494	biolink:NamedThing	regulation of butyryl-CoA biosynthetic process from acetyl-CoA	Any process that modulates the frequency, rate or extent of butyryl-CoA biosynthetic process from acetyl-CoA.	tmpzr1t_l9r_go_relaxed.owl	regulation of butyryl-CoA biosynthesis from acetyl-CoA							tt	2012-05-02T03:51:38Z					biological_process											owl:Class	
GO:0050812	biolink:NamedThing	regulation of acyl-CoA biosynthetic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of acyl-CoA.	tmpzr1t_l9r_go_relaxed.owl	regulation of acyl-CoA anabolism|regulation of acyl-CoA synthesis|regulation of acyl-CoA biosynthesis|regulation of acyl-CoA formation													biological_process											owl:Class	
GO:0031433	biolink:NamedThing	telethonin binding	Binding to telethonin, a protein found in the Z disc of striated muscle and which is a substrate of the titin kinase.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0001825	biolink:NamedThing	blastocyst formation	The initial formation of a blastocyst from a solid ball of cells known as a morula.	tmpzr1t_l9r_go_relaxed.owl						See also the Anatomical Dictionary for Mouse Development ontology term 'TS3, compacted morula ; EMAP:9'.								biological_process											owl:Class	
GO:0097250	biolink:NamedThing	mitochondrial respirasome assembly	The aggregation, arrangement and bonding together of a set of respiratory enzyme complexes of the mitochondrial inner membrane (including, for example, complex II, complex III, complex IV) to form a large supercomplex.	tmpzr1t_l9r_go_relaxed.owl	mitochondrial respiratory chain supercomplex assembly|mitochondrial respiratory supercomplex assembly	https://github.com/geneontology/go-ontology/issues/12846						pr	2012-02-23T05:18:41Z					biological_process											owl:Class	
GO:0007005	biolink:NamedThing	mitochondrion organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a mitochondrion; includes mitochondrial morphogenesis and distribution, and replication of the mitochondrial genome as well as synthesis of new mitochondrial components.	tmpzr1t_l9r_go_relaxed.owl	mitochondrion organisation|mitochondrion organization and biogenesis|mitochondria organization													biological_process											owl:Class	
GO:0005149	biolink:NamedThing	interleukin-1 receptor binding	Binding to an interleukin-1 receptor.	tmpzr1t_l9r_go_relaxed.owl	interleukin-1 receptor ligand|IL-1													molecular_function											owl:Class	
GO:0008911	biolink:NamedThing	lactaldehyde dehydrogenase activity	Catalysis of the reaction: (S)-lactaldehyde + NAD+ + H2O = (S)-lactate + NADH + H+.	tmpzr1t_l9r_go_relaxed.owl	L-lactaldehyde:NAD oxidoreductase activity|(S)-lactaldehyde:NAD+ oxidoreductase activity|nicotinamide adenine dinucleotide (NAD)-linked dehydrogenase activity				MetaCyc:LACTALDDEHYDROG-RXN|EC:1.2.1.22|RHEA:14277									molecular_function											owl:Class	
GO:1990863	biolink:NamedThing	acinar cell proliferation	The multiplication or reproduction of acinar cells, resulting in the expansion of a cell population. An acinar cell is a secretory cell that is grouped together with other cells of the same type to form grape-shaped clusters known as acini (singular acinus).	tmpzr1t_l9r_go_relaxed.owl	acinic cell proliferation|acinous cell proliferation							sl	2015-09-25T14:26:09Z					biological_process											owl:Class	
GO:0075043	biolink:NamedThing	melanization of appressorium wall	The process in which melanin is produced in the appressorium of the symbiont. Melanization of the appressorium increases turgor pressure in the appressorium.	tmpzr1t_l9r_go_relaxed.owl	melanization of appressorium to maintain turgor pressure|maintenance of turgor in appressorium by melanization	https://github.com/geneontology/go-ontology/issues/21505												biological_process											owl:Class	
GO:0035130	biolink:NamedThing	post-embryonic pectoral fin morphogenesis	The process, occurring after embryonic development, by which the anatomical structures of the pectoral fin are generated and organized. Pectoral fins are bilaterally paired fins mounted laterally and located behind the gill covers of fish. These fins are used for lateral mobility and propulsion.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0035138	biolink:NamedThing	pectoral fin morphogenesis	The process in which the anatomical structures of the pectoral fin are generated and organized. Pectoral fins are bilaterally paired fins mounted laterally and located behind the gill covers of fish. These fins are used for lateral mobility and propulsion.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0000415	biolink:NamedThing	negative regulation of histone H3-K36 methylation	Any process that stops, prevents, or reduces the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 36 of histone H3.	tmpzr1t_l9r_go_relaxed.owl	down regulation of histone H3-K36 methylation|downregulation of histone H3-K36 methylation|down-regulation of histone H3-K36 methylation|inhibition of histone H3-K36 methylation													biological_process											owl:Class	
GO:0031061	biolink:NamedThing	negative regulation of histone methylation	Any process that stops, prevents, or reduces the frequency, rate or extent of the covalent addition of methyl groups to histones.	tmpzr1t_l9r_go_relaxed.owl	inhibition of histone methylation|downregulation of histone methylation|down-regulation of histone methylation|down regulation of histone methylation													biological_process											owl:Class	
GO:0070832	biolink:NamedThing	phosphatidylcholine biosynthesis from phosphoryl-ethanolamine via N-dimethylethanolamine phosphate and CDP-choline	The phosphatidylcholine biosynthetic process that begins with three consecutive N-methylation steps that are carried out on phospho-bases, phosphoethanolamine, phospho-N-methylethanolamine, and phospho-N-dimethylethanolamine; the process ends with the conversion of a phosphatidyl-N-dimethylethanolamine to a phosphatidylcholine.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:PWY4FS-2			mah	2009-07-29T03:49:14Z					biological_process											owl:Class	
GO:0006656	biolink:NamedThing	phosphatidylcholine biosynthetic process	The chemical reactions and pathways resulting in the formation of phosphatidylcholines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of choline.	tmpzr1t_l9r_go_relaxed.owl	phosphatidylcholine biosynthesis|phosphatidylcholine anabolism|phosphatidylcholine synthesis|phosphatidylcholine formation													biological_process											owl:Class	
GO:0015205	biolink:NamedThing	nucleobase transmembrane transporter activity	Enables the transfer of a nucleobase, any nitrogenous base that is a constituent of a nucleoside, nucleotide, or nucleic acidfrom one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl												GO:0015392		molecular_function											owl:Class	
GO:1901076	biolink:NamedThing	positive regulation of engulfment of apoptotic cell	Any process that activates or increases the frequency, rate or extent of engulfment of apoptotic cell.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of engulfment of cell corpse|upregulation of engulfment of apoptotic cell|up-regulation of engulfment of apoptotic cell|up regulation of engulfment of apoptotic cell|positive regulation of engulfment of apoptotic cell corpse|upregulation of engulfment of cell corpse|up-regulation of engulfment of cell corpse|up-regulation of engulfment of apoptotic cell corpse|activation of engulfment of apoptotic cell|upregulation of engulfment of apoptotic cell corpse|activation of engulfment of cell corpse|activation of engulfment of apoptotic cell corpse|up regulation of engulfment of cell corpse|up regulation of engulfment of apoptotic cell corpse							kmv	2012-07-02T07:32:51Z					biological_process											owl:Class	
GO:2000427	biolink:NamedThing	positive regulation of apoptotic cell clearance	Any process that activates or increases the frequency, rate or extent of apoptotic cell clearance.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of programmed cell clearance|positive regulation of apoptotic cell removal|positive regulation of efferocytosis							bf	2011-02-25T11:50:59Z					biological_process											owl:Class	
GO:0044324	biolink:NamedThing	regulation of transcription involved in anterior/posterior axis specification	Any process that modulates the frequency, rate or extent of transcription that contributes to the specification of the anterior/posterior axis.	tmpzr1t_l9r_go_relaxed.owl								jl	2010-08-04T12:35:41Z					biological_process											owl:Class	
GO:0031229	biolink:NamedThing	intrinsic component of nuclear inner membrane	The component of the nuclear inner membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.	tmpzr1t_l9r_go_relaxed.owl	intrinsic to nuclear inner membrane													cellular_component											owl:Class	
GO:0102952	biolink:NamedThing	UDP-glucose:coniferaldehyde 4-beta-D-glucosyltransferase activity	Catalysis of the reaction: UDP-alpha-D-glucose + coniferyl aldehyde = H+ + coniferaldehyde glucoside + UDP.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-91|RHEA:57708									molecular_function											owl:Class	
GO:0036029	biolink:NamedThing	protein C inhibitor-KLK3 complex	A heterodimeric protein complex that contains protein C inhibitor (SERPINA5) and prostate-specific antigen (KLK3); formation of the complex inhibits the serine protease activity of prostate-specific antigen.	tmpzr1t_l9r_go_relaxed.owl	serpin A5-KLK3 complex|SERPINA5-KLK3 complex|protein C inhibitor-prostate-specific antigen complex|plasma serine protease inhibitor-KLK3 complex|protein C inhibitor-kallikrein-3 complex|PCI-KLK3 complex							bf	2011-10-19T02:01:33Z					cellular_component											owl:Class	
GO:0015173	biolink:NamedThing	aromatic amino acid transmembrane transporter activity	Enables the transfer of aromatic amino acids from one side of a membrane to the other. Aromatic amino acids have an aromatic ring.	tmpzr1t_l9r_go_relaxed.owl	aromatic amino acid transporter activity|hydroxy/aromatic amino acid permease activity|valine/tyrosine/tryptophan permease activity													molecular_function											owl:Class	
GO:0051502	biolink:NamedThing	diterpene phytoalexin biosynthetic process	The chemical reactions and pathways resulting in the formation of diterpene phytoalexins, terpenoids with 20 carbons produced by plants in response to environmental stresses.	tmpzr1t_l9r_go_relaxed.owl	diterpene phytoalexin biosynthesis|diterpene phytoalexin anabolism|diterpene phytoalexin formation|diterpene phytoalexin synthesis													biological_process											owl:Class	
GO:0097687	biolink:NamedThing	dinoflagellate antapical horn	A horn-shaped dinoflagellate antapex found in thecate species.	tmpzr1t_l9r_go_relaxed.owl								pr	2014-12-18T09:39:57Z					cellular_component											owl:Class	
GO:0030704	biolink:NamedThing	vitelline membrane formation	Construction of the vitelline membrane portion of the egg shell, a rigid structure required to maintain the shape of the egg.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0085029	biolink:NamedThing	extracellular matrix assembly	The aggregation, arrangement and bonding together of the extracellular matrix.	tmpzr1t_l9r_go_relaxed.owl								jl	2010-07-14T12:52:49Z					biological_process											owl:Class	
GO:0004414	biolink:NamedThing	homoserine O-acetyltransferase activity	Catalysis of the reaction: L-homoserine + acetyl-CoA = O-acetyl-L-homoserine + CoA.	tmpzr1t_l9r_go_relaxed.owl	homoserine O-trans-acetylase activity|homoserine acetyltransferase activity|homoserine transacetylase activity|L-homoserine O-acetyltransferase activity|homoserine-O-transacetylase activity|acetyl-CoA:L-homoserine O-acetyltransferase activity				MetaCyc:HOMOSERINE-O-ACETYLTRANSFERASE-RXN|EC:2.3.1.31|RHEA:13701|KEGG_REACTION:R01776									molecular_function											owl:Class	
GO:0061863	biolink:NamedThing	microtubule plus end polymerase	Catalysis of the transfer of tubulin dimers to the plus end of a microtubule. The reaction is reversable depending on the availability of dimers.	tmpzr1t_l9r_go_relaxed.owl								dph	2017-04-07T17:36:57Z					molecular_function											owl:Class	
GO:0072097	biolink:NamedThing	negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway	A series of molecular signals generated as a consequence of any member of the BMP (bone morphogenetic protein) family binding to a cell surface receptor resulting in the reduction of the frequency, rate or extent of branch elongation involved in ureteric bud branching, the growth of a branch of the ureteric bud along its axis.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of branch elongation involved in ureteric bud branching by BMP signalling pathway							mah	2010-02-10T02:00:34Z					biological_process											owl:Class	
GO:0018096	biolink:NamedThing	peptide cross-linking via S-(2-aminovinyl)-D-cysteine	The synthesis of (S,Z)-S-(2-aminovinyl)cysteine forming an intra-polypeptide cross-link between serine and cysteine.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0204									biological_process											owl:Class	
GO:1900985	biolink:NamedThing	vindoline biosynthetic process	The chemical reactions and pathways resulting in the formation of vindoline.	tmpzr1t_l9r_go_relaxed.owl	vindoline anabolism|vindoline synthesis|vindoline formation|vindoline biosynthesis							yaf	2012-06-14T09:17:03Z					biological_process											owl:Class	
GO:0032091	biolink:NamedThing	negative regulation of protein binding	Any process that stops, prevents, or reduces the frequency, rate or extent of protein binding.	tmpzr1t_l9r_go_relaxed.owl	down regulation of protein binding|downregulation of protein binding|down-regulation of protein binding|inhibition of protein binding													biological_process											owl:Class	
GO:0052761	biolink:NamedThing	exo-1,4-beta-D-glucosaminidase activity	Catalysis of the reaction: [beta-(1->4)-D-glucosamine]n-[N-acetyl-D-glucosamine]m = D-glucosamine + [beta-(1->4)-D-glucosamine](n-1)-[N-acetyl-D-glucosamine]m. This reaction is the hydrolysis of chitosan or chitosan oligosaccharides to remove a D-glucosamine residue from the non-reducing termini; chitosan is a linear polysaccharide composed of randomly distributed beta-(1->4)-linked D-glucosamine and N-acetyl-D-glucosamine units.	tmpzr1t_l9r_go_relaxed.owl	chitosan glucosaminohydrolase activity|chitosan exo-1,4-beta-D-glucosaminidase activity|exo-beta-D-glucosaminidase activity|exochitosanase activity				MetaCyc:3.2.1.165-RXN|KEGG_REACTION:R08715|EC:3.2.1.165			ai	2011-09-28T03:30:54Z					molecular_function											owl:Class	
GO:1904109	biolink:NamedThing	positive regulation of cholesterol import	Any process that activates or increases the frequency, rate or extent of cholesterol import.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of cholesterol import|activation of cholesterol uptake|up regulation of cholesterol import|upregulation of cholesterol uptake|up regulation of cholesterol uptake|activation of cholesterol import|upregulation of cholesterol import|positive regulation of cholesterol uptake|up-regulation of cholesterol uptake							sl	2015-04-03T14:39:06Z					biological_process											owl:Class	
GO:0045116	biolink:NamedThing	protein neddylation	Covalent attachment of the ubiquitin-like protein NEDD8 (RUB1) to another protein.	tmpzr1t_l9r_go_relaxed.owl	RUB1-protein conjugation					Note that currently, the only known substrates of neddylation are cullin family proteins.						GO:0019943		biological_process											owl:Class	
GO:1904723	biolink:NamedThing	negative regulation of Wnt-Frizzled-LRP5/6 complex assembly	Any process that stops, prevents or reduces the frequency, rate or extent of Wnt-Frizzled-LRP5/6 complex assembly.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of WNT-FZD-LRP6 complex assembly|negative regulation of WNT-FZD-LRP6 complex assembly|negative regulation of Frizzled-LRP5/6 complex assembly|down regulation of Wnt-FZD-LRP5/6 trimeric complex assembly|down-regulation of WNT-FZD-LRP6 complex formation|down regulation of WNT-FZD-LRP6 complex formation|negative regulation of WNT-FZD-LRP5 complex assembly|inhibition of WNT-FZD-LRP5 complex formation|down-regulation of WNT-FZD-LRP5 complex formation|downregulation of Frizzled-LRP5/6 complex assembly|down regulation of WNT-FZD-LRP5 complex formation|downregulation of Wnt-FZD-LRP5/6 trimeric complex assembly|inhibition of WNT-FZD-LRP6 complex assembly|downregulation of Wnt-induced Frizzled-LRP5/6 complex formation|down regulation of Wnt-induced Frizzled-LRP5/6 complex assembly|down-regulation of Wnt-FZD-LRP5/6 trimeric complex assembly|downregulation of WNT-FZD-LRP6 complex formation|negative regulation of Wnt-induced Frizzled-LRP5/6 complex assembly|negative regulation of WNT-FZD-LRP6 complex formation|downregulation of Wnt-FZD-LRP5/6 trimeric complex formation|downregulation of WNT-FZD-LRP6 complex assembly|downregulation of WNT-FZD-LRP5 complex assembly|down-regulation of Wnt-induced Frizzled-LRP5/6 complex formation|down-regulation of Wnt-induced Frizzled-LRP5/6 complex assembly|inhibition of WNT-FZD-LRP6 complex formation|inhibition of Frizzled-LRP5/6 complex assembly|inhibition of Wnt-FZD-LRP5/6 trimeric complex formation|down regulation of WNT-FZD-LRP6 complex assembly|down regulation of Frizzled-LRP5/6 complex formation|down regulation of WNT-FZD-LRP5 complex assembly|down regulation of Frizzled-LRP5/6 complex assembly|down-regulation of Wnt-FZD-LRP5/6 trimeric complex formation|down-regulation of Frizzled-LRP5/6 complex assembly|negative regulation of Wnt-induced Frizzled-LRP5/6 complex formation|down-regulation of Frizzled-LRP5/6 complex formation|downregulation of WNT-FZD-LRP5 complex formation|negative regulation of Frizzled-LRP5/6 complex formation|inhibition of WNT-FZD-LRP5 complex assembly|negative regulation of Wnt-FZD-LRP5/6 trimeric complex assembly|down-regulation of WNT-FZD-LRP5 complex assembly|downregulation of Frizzled-LRP5/6 complex formation|down regulation of Wnt-FZD-LRP5/6 trimeric complex formation|negative regulation of Wnt-FZD-LRP5/6 trimeric complex formation|down regulation of Wnt-induced Frizzled-LRP5/6 complex formation|inhibition of Wnt-FZD-LRP5/6 trimeric complex assembly|inhibition of Wnt-induced Frizzled-LRP5/6 complex assembly|downregulation of Wnt-induced Frizzled-LRP5/6 complex assembly|negative regulation of WNT-FZD-LRP5 complex formation|inhibition of Frizzled-LRP5/6 complex formation|inhibition of Wnt-induced Frizzled-LRP5/6 complex formation							bf	2015-10-12T08:14:59Z					biological_process											owl:Class	
GO:0008986	biolink:NamedThing	pyruvate, water dikinase activity	Catalysis of the reaction: ATP + H(2)O + pyruvate = AMP + 3 H(+) + phosphate + phosphoenolpyruvate.	tmpzr1t_l9r_go_relaxed.owl	phosphoenolpyruvate synthase activity|phosphoenolpyruvic synthase activity|phosphopyruvate synthetase activity|phoephoenolpyruvate synthetase activity|pyruvate,water dikinase activity|PEP synthetase activity|pyruvate-water dikinase (phosphorylating)|PEP synthase activity|ATP:pyruvate, water phosphotransferase activity|water pyruvate dikinase activity				KEGG_REACTION:R00199|EC:2.7.9.2|RHEA:11364|MetaCyc:PEPSYNTH-RXN									molecular_function											owl:Class	
GO:0070718	biolink:NamedThing	alphaPDGFR-SHP-2 complex	A protein complex that contains the platelet-derived growth factor alpha receptor (alphaPDGFR; PDGFRA) and the adaptor protein SHP-2, and is involved signaling via the PDGFR signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	PDGFRA-SHP-2 complex, PDGF stimulated							mah	2009-06-10T05:00:43Z					cellular_component											owl:Class	
GO:0031523	biolink:NamedThing	Myb complex	A multisubunit complex consisting of Myb and other proteins that regulates site specific DNA replication, gene amplification and transcriptional repression.	tmpzr1t_l9r_go_relaxed.owl	Myeloblastosis proto-oncogene protein complex													cellular_component											owl:Class	
GO:1902661	biolink:NamedThing	positive regulation of glucose mediated signaling pathway	Any process that activates or increases the frequency, rate or extent of glucose mediated signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	activation of glucose mediated signalling|activation of glucose mediated signaling pathway|up-regulation of glucose mediated signaling pathway|upregulation of glucose mediated signalling|up regulation of glucose mediated signaling pathway|upregulation of glucose mediated signaling pathway|up-regulation of glucose mediated signalling|up regulation of glucose mediated signalling|positive regulation of glucose mediated signalling							di	2014-01-28T17:54:47Z					biological_process											owl:Class	
GO:0072514	biolink:NamedThing	trehalose transport in response to water deprivation	The directed movement of trehalose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore, that occurs as a result of deprivation of water.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-12-21T11:26:14Z					biological_process											owl:Class	
GO:0035560	biolink:NamedThing	pheophorbidase activity	Catalysis of the reaction: pheophorbide a + H2O = pyropheophorbide a + methanol + CO2. The reaction occurs in two steps; pheophoridase catalyzes the conversion of pheophorbide a to a precursor of pyropheophorbide a, C-13(2)-carboxylpyropheophorbide a, by demethylation, and then the precursor is decarboxylated non-enzymatically to yield pyropheophorbide a.	tmpzr1t_l9r_go_relaxed.owl	pheophoridase activity|PPD activity|phedase activity				RHEA:32483|EC:3.1.1.82			bf	2010-05-14T02:39:58Z					molecular_function											owl:Class	
GO:0002821	biolink:NamedThing	positive regulation of adaptive immune response	Any process that activates or increases the frequency, rate, or extent of an adaptive immune response.	tmpzr1t_l9r_go_relaxed.owl	activation of adaptive immune response|up-regulation of adaptive immune response|stimulation of adaptive immune response|up regulation of adaptive immune response|upregulation of adaptive immune response													biological_process											owl:Class	
GO:0035743	biolink:NamedThing	CD4-positive, alpha-beta T cell cytokine production	Any process that contributes to cytokine production by a CD4-positive, alpha-beta T cell.	tmpzr1t_l9r_go_relaxed.owl						Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.		bf	2011-03-17T02:21:51Z					biological_process											owl:Class	
GO:0062083	biolink:NamedThing	HLA-G specific inhibitory MHC class Ib receptor activity	Combining with a MHC class Ib molecule of the HLA-G subclass to mediate signaling that inhibits activation of a lymphocyte.	tmpzr1t_l9r_go_relaxed.owl								dph	2018-10-15T15:06:44Z					molecular_function											owl:Class	
GO:0062080	biolink:NamedThing	inhibitory MHC class Ib receptor activity	Combining with a MHC class Ib protein complex to mediate signaling that inhibits activation of a lymphocyte.	tmpzr1t_l9r_go_relaxed.owl								dph	2018-10-15T15:03:44Z					molecular_function											owl:Class	
GO:0033431	biolink:NamedThing	CGA codon-amino acid adaptor activity	A triplet codon-amino acid adaptor activity that recognizes a CGA codon.	tmpzr1t_l9r_go_relaxed.owl	arginine tRNA					Note that in the standard genetic code, CGA codes for arginine.								molecular_function											owl:Class	
GO:0046720	biolink:NamedThing	citric acid secretion	The controlled release of citric acid, 2-hydroxy-1,2,3-propanetricarboxylic acid, by a cell or a tissue.	tmpzr1t_l9r_go_relaxed.owl	citrate secretion													biological_process											owl:Class	
GO:0061267	biolink:NamedThing	mesonephric interstitial fibroblast development	The process whose specific outcome is the progression of a mesonephric interstitial fibroblast over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl	mesonephros interstitial cell development							dph	2010-08-30T03:14:31Z					biological_process											owl:Class	
GO:2000912	biolink:NamedThing	regulation of galactoglucomannan catabolic process	Any process that modulates the frequency, rate or extent of galactoglucomannan catabolic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of galactoglucomannan catabolism							tt	2011-07-29T07:51:31Z					biological_process											owl:Class	
GO:0005853	biolink:NamedThing	eukaryotic translation elongation factor 1 complex	A multisubunit nucleotide exchange complex that binds GTP and aminoacyl-tRNAs, and catalyzes their codon-dependent placement at the A-site of the ribosome. In humans, the complex is composed of four subunits, alpha, beta, delta and gamma.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0035459	biolink:NamedThing	vesicle cargo loading	The formation of a macromolecular complex between the coat proteins and proteins and/or lipoproteins that are going to be transported by a vesicle.	tmpzr1t_l9r_go_relaxed.owl	cargo loading into vesicle|cargo selection							bf	2010-04-16T01:14:06Z					biological_process											owl:Class	
GO:0045838	biolink:NamedThing	positive regulation of membrane potential	Any process that activates or increases the frequency, rate or extent of establishment or extent of a membrane potential, the electric potential existing across any membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane.	tmpzr1t_l9r_go_relaxed.owl	activation of membrane potential|stimulation of membrane potential|elevation of membrane potential|up-regulation of membrane potential|upregulation of membrane potential|up regulation of membrane potential													biological_process											owl:Class	
GO:0071439	biolink:NamedThing	clathrin complex	A protein complex that consists of three clathrin heavy chains and three clathrin light chains, organized into a symmetrical three-legged structure called a triskelion. In clathrin-coated vesicles clathrin is the main component of the coat and forms a polymeric mechanical scaffold on the vesicle surface.	tmpzr1t_l9r_go_relaxed.owl	clathrin triskelion							mah	2009-12-16T03:17:58Z					cellular_component											owl:Class	
GO:1990693	biolink:NamedThing	intrinsic component of Golgi cis cisterna membrane	The component of the Golgi cis cisterna membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.	tmpzr1t_l9r_go_relaxed.owl	intrinsic component of cis-Golgi cisterna membrane							bhm	2015-03-12T10:24:07Z					cellular_component											owl:Class	
GO:0048669	biolink:NamedThing	collateral sprouting in absence of injury	The process in which outgrowths develop from the axons of intact undamaged neurons.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0071745	biolink:NamedThing	IgA immunoglobulin complex	A protein complex composed of two identical immunoglobulin heavy chains of the IgA isotype and two identical immunoglobulin light chains, held together by disulfide bonds, and sometimes complexed with J chain or J chain and secretory component. An IgA immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.	tmpzr1t_l9r_go_relaxed.owl	IgA2 antibody|IgA1 antibody					Note that an IgA immunoglobulin complex has the function of antigen binding if a suitable antigen is available.		mah	2010-03-24T01:44:53Z					cellular_component											owl:Class	
GO:0071129	biolink:NamedThing	alphaV-beta3 integrin-LPP3 complex	A protein complex that consists of an alphaV-beta3 integrin complex bound to lipid phosphate phosphohydrolase-3.	tmpzr1t_l9r_go_relaxed.owl	ITGAV-ITGB3-PPAP2B complex							mah	2009-11-13T02:25:17Z					cellular_component											owl:Class	
GO:0031796	biolink:NamedThing	type 1 metabotropic GABA receptor binding	Binding to a type 1 metabotropic GABA receptor.	tmpzr1t_l9r_go_relaxed.owl	type 1 metabotropic GABA receptor ligand													molecular_function											owl:Class	
GO:0046679	biolink:NamedThing	response to streptomycin	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a streptomycin stimulus. Streptomycin is a commonly used antibiotic in cell culture media which acts only on prokaryotes and blocks transition from initiation complex to chain elongating ribosome.	tmpzr1t_l9r_go_relaxed.owl	streptomycin susceptibility/resistance													biological_process											owl:Class	
GO:0071669	biolink:NamedThing	plant-type cell wall organization or biogenesis	A process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a cellulose- and pectin-containing cell wall.	tmpzr1t_l9r_go_relaxed.owl	plant-type cell wall organization and biogenesis|plant-type cell wall organisation or biogenesis							mah	2010-02-15T02:32:10Z					biological_process											owl:Class	
GO:0018872	biolink:NamedThing	arsonoacetate metabolic process	The chemical reactions and pathways involving arsonoacetate, a synthetic, organic compound containing a single arsenic atom. Arsonoacetate and other arsenic containing compounds are used in agricultural applications as animal feed additives, cotton defoliants and post-emergence grass herbicides.	tmpzr1t_l9r_go_relaxed.owl	arsonoacetate metabolism				UM-BBD_pathwayID:ara									biological_process											owl:Class	
GO:0047842	biolink:NamedThing	dehydro-L-gulonate decarboxylase activity	Catalysis of the reaction: 3-dehydro-L-gulonate + H(+) = L-xylulose + CO(2).	tmpzr1t_l9r_go_relaxed.owl	3-dehydro-L-gulonate carboxy-lyase activity|3-keto-L-gulonate decarboxylase activity|3-dehydro-L-gulonate carboxy-lyase (L-xylulose-forming)|keto-L-gulonate decarboxylase activity				Reactome:R-HSA-5662473|MetaCyc:DEHYDRO-L-GULONATE-DECARBOXYLASE-RXN|RHEA:11084|KEGG_REACTION:R01905|EC:4.1.1.34									molecular_function											owl:Class	
GO:2000927	biolink:NamedThing	regulation of cellodextrin catabolic process	Any process that modulates the frequency, rate or extent of cellodextrin catabolic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of cellodextrin catabolism							tt	2011-08-01T12:41:29Z					biological_process											owl:Class	
GO:0007352	biolink:NamedThing	zygotic specification of dorsal/ventral axis	The specification of the dorsal/ventral axis of the embryo, through the products of genes expressed in the zygote.	tmpzr1t_l9r_go_relaxed.owl	zygotic determination of dorsal-ventral axis|zygotic determination of dorsoventral axis|zygotic determination of dorsal/ventral axis													biological_process											owl:Class	
GO:0009950	biolink:NamedThing	dorsal/ventral axis specification	The establishment, maintenance and elaboration of the dorsal/ventral axis. The dorsal/ventral axis is defined by a line that runs orthogonal to both the anterior/posterior and left/right axes. The dorsal end is defined by the upper or back side of an organism. The ventral end is defined by the lower or front side of an organism.	tmpzr1t_l9r_go_relaxed.owl	dorsal/ventral axis determination|dorsal-ventral axis specification|dorsoventral axis specification													biological_process											owl:Class	
GO:1903297	biolink:NamedThing	regulation of hypoxia-induced intrinsic apoptotic signaling pathway	Any process that modulates the frequency, rate or extent of hypoxia-induced intrinsic apoptotic signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	regulation of hypoxia-induced apoptosis|regulation of intrinsic apoptotic signaling pathway in response to hypoxia|regulation of hypoxic stress-induced intrinsic apoptotic signaling pathway							bf	2014-08-14T14:47:48Z					biological_process											owl:Class	
GO:0090649	biolink:NamedThing	response to oxygen-glucose deprivation	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the deprivation of oxygen and glucose.	tmpzr1t_l9r_go_relaxed.owl	response to OGD							tb	2015-07-01T10:27:29Z					biological_process											owl:Class	
GO:0036293	biolink:NamedThing	response to decreased oxygen levels	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting a decline in the level of oxygen.	tmpzr1t_l9r_go_relaxed.owl	response to lowered oxygen levels					This term should be used when a decrease in oxygen levels is not considered a stress response. For a hypoxic stress response, consider instead 'response to hypoxia ; GO:0001666'.		bf	2012-07-20T01:05:46Z					biological_process											owl:Class	
GO:1903384	biolink:NamedThing	negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway	Any process that stops, prevents or reduces the frequency, rate or extent of a hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of neuron apoptosis in response to hydrogen peroxide|down-regulation of neuron intrinsic apoptotic signaling pathway in response to H2O2|down regulation of H2O2-induced neuron intrinsic apoptotic signaling pathway|downregulation of H2O2-induced neuron intrinsic apoptotic signaling pathway|inhibition of H2O2-induced neuron intrinsic apoptotic signaling pathway|negative regulation of neuron intrinsic apoptotic signaling pathway in response to hydrogen peroxide|inhibition of neuron intrinsic apoptotic signaling pathway in response to H2O2|protection against hydrogen peroxide-induced neuron apoptosis|inhibition of neuron intrinsic apoptotic signaling pathway in response to hydrogen peroxide|down regulation of neuron intrinsic apoptotic signaling pathway in response to hydrogen peroxide|down regulation of neuron intrinsic apoptotic signaling pathway in response to H2O2|down-regulation of neuron intrinsic apoptotic signaling pathway in response to hydrogen peroxide|downregulation of neuron intrinsic apoptotic signaling pathway in response to H2O2|inhibition of neuron apoptosis in response to hydrogen peroxide|downregulation of neuron apoptosis in response to hydrogen peroxide|negative regulation of neuron intrinsic apoptotic signaling pathway in response to H2O2|negative regulation of H2O2-induced neuron intrinsic apoptotic signaling pathway|down regulation of neuron apoptosis in response to hydrogen peroxide|down-regulation of neuron apoptosis in response to hydrogen peroxide|protection against H2O2-induced neuron apoptosis|downregulation of neuron intrinsic apoptotic signaling pathway in response to hydrogen peroxide|down-regulation of H2O2-induced neuron intrinsic apoptotic signaling pathway							bf	2014-08-27T08:50:45Z					biological_process											owl:Class	
GO:0009252	biolink:NamedThing	peptidoglycan biosynthetic process	The chemical reactions and pathways resulting in the formation of peptidoglycans, any of a class of glycoconjugates found in bacterial cell walls.	tmpzr1t_l9r_go_relaxed.owl	peptidoglycan synthesis|murein biosynthesis|peptidoglycan biosynthesis|peptidoglycan anabolism|murein biosynthetic process|peptidoglycan formation											GO:0009285		biological_process											owl:Class	
GO:1990772	biolink:NamedThing	substance P secretion	The regulated release of substance P, a peptide hormone that is involved in neurotransmission, inflammation, and antimicrobial activity.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-06-15T18:17:30Z					biological_process											owl:Class	
GO:1905460	biolink:NamedThing	negative regulation of vascular associated smooth muscle cell apoptotic process	Any process that stops, prevents or reduces the frequency, rate or extent of vascular associated smooth muscle cell apoptotic process.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of vascular smooth muscle cell apoptotic process|down-regulation of VSMC apoptotic process|inhibition of vascular smooth muscle cell apoptosis|downregulation of VSMC apoptotic process|down-regulation of vascular smooth muscle cell apoptosis|downregulation of vascular associated smooth muscle cell apoptotic process|inhibition of vascular associated smooth muscle cell apoptotic process|down regulation of vascular associated smooth muscle cell apoptosis|down regulation of VSMC apoptosis|inhibition of VSMC apoptotic process|negative regulation of vascular smooth muscle cell apoptosis|down-regulation of vascular smooth muscle cell apoptotic process|negative regulation of VSMC apoptosis|down regulation of VSMC apoptotic process|downregulation of vascular smooth muscle cell apoptotic process|down-regulation of vascular associated smooth muscle cell apoptotic process|down regulation of vascular smooth muscle cell apoptosis|down regulation of vascular associated smooth muscle cell apoptotic process|down-regulation of vascular associated smooth muscle cell apoptosis|negative regulation of VSMC apoptotic process|inhibition of VSMC apoptosis|downregulation of vascular associated smooth muscle cell apoptosis|negative regulation of vascular associated smooth muscle cell apoptosis|downregulation of vascular smooth muscle cell apoptosis|down-regulation of VSMC apoptosis|down regulation of vascular smooth muscle cell apoptotic process|inhibition of vascular associated smooth muscle cell apoptosis|inhibition of vascular smooth muscle cell apoptotic process|downregulation of VSMC apoptosis							rph	2016-09-19T11:34:03Z					biological_process											owl:Class	
GO:0009714	biolink:NamedThing	chalcone metabolic process	The chemical reactions and pathways involving chalcones, phenyl steryl ketone or its hydroxylated derivatives.	tmpzr1t_l9r_go_relaxed.owl	chalcone metabolism													biological_process											owl:Class	
GO:0033548	biolink:NamedThing	myo-inositol hexakisphosphate biosynthetic process, lipid-independent	The chemical reactions and pathways resulting in the formation of phytic acid, myo-inositol hexakisphosphate, by the successively phosphorylation of myo-inositol or an inositol trisphosphate; the inositol trisphosphates that may be used by this pathway are inositol 3,4,5-trisphosphate and inositol 3,4,6trisphosphate.	tmpzr1t_l9r_go_relaxed.owl	myo-inositol hexakisphosphate biosynthesis, lipid-independent|phytate biosynthetic process, lipid-independent|myo-inositol hexakisphosphate synthesis, lipid-independent|myo-inositol hexakisphosphate formation, lipid-independent|myo-inositol hexakisphosphate anabolism, lipid-independent|phytate biosynthesis, lipid-independent				MetaCyc:PWY-4661									biological_process											owl:Class	
GO:0010264	biolink:NamedThing	myo-inositol hexakisphosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of phytic acid, myo-inositol hexakisphosphate, a regulator of intracellular signaling, a highly abundant animal anti-nutrient and a phosphate and mineral storage compound in plant seeds.	tmpzr1t_l9r_go_relaxed.owl	myo-inositol hexakisphosphate anabolism|phytate biosynthetic process|myo-inositol hexakisphosphate synthesis|myo-inositol hexakisphosphate formation|phytate biosynthesis|myo-inositol hexakisphosphate biosynthesis													biological_process											owl:Class	
GO:1902746	biolink:NamedThing	regulation of lens fiber cell differentiation	Any process that modulates the frequency, rate or extent of lens fiber cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	regulation of lens fibre cell differentiation							mr	2014-03-03T23:18:50Z					biological_process											owl:Class	
GO:0002547	biolink:NamedThing	positive regulation of tissue kallikrein-kinin cascade	Any process that activates or increases the frequency, rate, or extent of the tissue kallikrein-kinin cascade.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of glandular kallikrein-kinin cascade|stimulation of tissue kallikrein-kinin cascade|activation of tissue kallikrein-kinin cascade|upregulation of tissue kallikrein-kinin cascade|up regulation of tissue kallikrein-kinin cascade|up-regulation of tissue kallikrein-kinin cascade													biological_process											owl:Class	
GO:0075042	biolink:NamedThing	negative regulation of establishment of turgor in appressorium	Any process that stops, prevents, or reduces the frequency, rate or extent of turgor formation in the symbiont appressorium.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0043307	biolink:NamedThing	eosinophil activation	The change in morphology and behavior of a eosinophil resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:2001316	biolink:NamedThing	kojic acid metabolic process	The chemical reactions and pathways involving kojic acid.	tmpzr1t_l9r_go_relaxed.owl	5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one metabolism|C6H6O4 metabolism|kojic acid metabolism|5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one metabolic process|C6H6O4 metabolic process							bf	2012-04-18T09:22:42Z					biological_process											owl:Class	
GO:0004767	biolink:NamedThing	sphingomyelin phosphodiesterase activity	Catalysis of the reaction: H(2)O + sphingomyelin = ceramide + choline phosphate + H(+).	tmpzr1t_l9r_go_relaxed.owl	sphingomyelin cholinephosphohydrolase activity|sphingomyelinase activity				MetaCyc:SPHINGOMYELIN-PHOSPHODIESTERASE-RXN|Reactome:R-HSA-1605797|Reactome:R-HSA-1606273|Reactome:R-HSA-1640164|Reactome:R-HSA-1606288|EC:3.1.4.12|KEGG_REACTION:R02541|Reactome:R-HSA-193706|RHEA:19253							GO:0030231|GO:0030230		molecular_function											owl:Class	
GO:2000619	biolink:NamedThing	negative regulation of histone H4-K16 acetylation	Any process that stops, prevents or reduces the frequency, rate or extent of histone H4-K16 acetylation.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of histone H4 acetylation at K16							vk	2011-04-18T03:19:27Z					biological_process											owl:Class	
GO:0034604	biolink:NamedThing	pyruvate dehydrogenase (NAD+) activity	Catalysis of the reaction: pyruvate + CoA + NAD+ = acetyl-CoA + CO2 + NADH.	tmpzr1t_l9r_go_relaxed.owl					RHEA:28042|MetaCyc:PYRUVDEH-RXN|KEGG_REACTION:R00209									molecular_function											owl:Class	
GO:0030291	biolink:NamedThing	protein serine/threonine kinase inhibitor activity	Binds to and stops, prevents or reduces the activity of a protein serine/threonine kinase.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1901245	biolink:NamedThing	positive regulation of toll-like receptor 9 signaling pathway by B cell receptor internalization	The movement of a B cell receptor (BCR) from the plasma membrane to the inside of the cell, which results in positive regulation of toll-like receptor 9 (TLR9) signaling. For example, internalized BCR signals to recruit TLR9 from multiple small endosomes to large autophagosome-like compartments to enhance TLR9 signaling.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of toll-like receptor 9 signaling pathway by BCR endocytosis|positive regulation of TLR9 signaling pathway by B cell receptor internalization|positive regulation of toll-like receptor 9 signalling pathway by BCR endocytosis|positive regulation of toll-like receptor 9 signalling pathway by BCR receptor internalization|positive regulation of TLR9 signaling pathway by BCR endocytosis|positive regulation of TLR9 signaling pathway by BCR receptor internalization|BCR-induced TLR9 recruitment|positive regulation of toll-like receptor 9 signaling pathway by BCR receptor internalization|positive regulation of toll-like receptor 9 signalling pathway by B cell receptor internalization							bf	2012-08-08T08:12:44Z					biological_process											owl:Class	
GO:0036300	biolink:NamedThing	B cell receptor internalization	A receptor-mediated endocytosis process that results in the movement of a B cell receptor from the plasma membrane to the inside of the cell.	tmpzr1t_l9r_go_relaxed.owl	B cell receptor uptake of antigen|BCR endocytosis|BCR receptor internalization							bf	2012-08-07T11:24:20Z					biological_process											owl:Class	
GO:1900134	biolink:NamedThing	negative regulation of renin secretion into blood stream	Any process that stops, prevents or reduces the frequency, rate or extent of renin secretion into blood stream.	tmpzr1t_l9r_go_relaxed.owl	down regulation of renin release into blood stream|down regulation of renin secretion into blood stream|inhibition of renin secretion into blood stream|downregulation of renin release into blood stream|inhibition of renin release into blood stream|negative regulation of renin release into blood stream|down-regulation of renin release into blood stream|down-regulation of renin secretion into blood stream|downregulation of renin secretion into blood stream							rph	2012-02-27T10:32:05Z					biological_process											owl:Class	
GO:0019141	biolink:NamedThing	2-dehydropantolactone reductase (B-specific) activity	Catalysis of the reaction: (R)-pantolactone + NADP+ = 2-dehydropantolactone + NADPH + H+. The reaction is B-specific (i.e. the pro-S hydrogen is transferred from the 4-position of reduced nicotinamide cofactor) with respect to NADP+.	tmpzr1t_l9r_go_relaxed.owl	(R)-pantolactone:NADP+ oxidoreductase (B-specific)|2-oxopantoyl lactone reductase|2-ketopantoyl lactone reductase activity|2-dehydropantoyl-lactone reductase (B-specific) activity|ketopantoyl lactone reductase activity				EC:1.1.1.214|MetaCyc:DEHYDROPANTLACRED-RXN									molecular_function											owl:Class	
GO:0050324	biolink:NamedThing	taurocyamine kinase activity	Catalysis of the reaction: ATP + taurocyamine = N-phosphotaurocyamine + ADP + 2 H(+).	tmpzr1t_l9r_go_relaxed.owl	taurocyamine phosphotransferase activity|ATP:taurocyamine N-phosphotransferase activity|ATP:taurocyamine phosphotransferase activity				KEGG_REACTION:R03785|RHEA:22516|MetaCyc:TAUROCYAMINE-KINASE-RXN|EC:2.7.3.4									molecular_function											owl:Class	
GO:0015491	biolink:NamedThing	cation:cation antiporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: cation A(out) + cation B(in) = cation A(in) + cation B(out).	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0110081	biolink:NamedThing	negative regulation of placenta blood vessel development	Any process that stops, prevents or reduces the frequency, rate or extent of placenta blood vessel development.	tmpzr1t_l9r_go_relaxed.owl								kmv	2018-02-01T15:01:11Z					biological_process											owl:Class	
GO:1902502	biolink:NamedThing	multivesicular body HOPS complex	Any HOPS complex that is part of a multivesicular body membrane.	tmpzr1t_l9r_go_relaxed.owl	multivesicular body membrane HOPS complex							tb	2013-11-14T00:10:08Z					cellular_component											owl:Class	
GO:0030897	biolink:NamedThing	HOPS complex	A multimeric protein complex that associates with the vacuolar membrane, late endosomal (multivesicular body) and lysosomal membranes. HOPS is a tethering complex involved in vesicle fusion.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0021531	biolink:NamedThing	spinal cord radial glial cell differentiation	The process in which neuroepithelial cells in the ventral neural tube acquire specialized structural and/or functional features of radial glial cells. Radial cell precursors differentiate into both neuronal cell types and mature radial glial cells. Mature radial glial cells regulate the axon growth and pathfinding processes that occur during white matter patterning of the developing spinal cord. Differentiation includes the processes involved in commitment of a cell to a specific fate.	tmpzr1t_l9r_go_relaxed.owl	radial glial cell differentiation in spinal cord													biological_process											owl:Class	
GO:0060019	biolink:NamedThing	radial glial cell differentiation	The process in which neuroepithelial cells of the neural tube give rise to radial glial cells, specialized bipotential progenitors cells of the brain. Differentiation includes the processes involved in commitment of a cell to a specific fate.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0009259	biolink:NamedThing	ribonucleotide metabolic process	The chemical reactions and pathways involving a ribonucleotide, a compound consisting of ribonucleoside (a base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.	tmpzr1t_l9r_go_relaxed.owl	ribonucleotide metabolism											GO:0009121		biological_process											owl:Class	
GO:0048464	biolink:NamedThing	flower calyx development	The process whose specific outcome is the progression of the flower calyx over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0060677	biolink:NamedThing	ureteric bud elongation	The developmental growth in which the ureteric bud grows along its axis beginning with the growth of the primary ureteric bud and ending when the branches of the bud have elongated.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-06-02T02:13:29Z					biological_process											owl:Class	
GO:0006323	biolink:NamedThing	DNA packaging	Any process in which DNA and associated proteins are formed into a compact, orderly structure.	tmpzr1t_l9r_go_relaxed.owl	DNA organisation|DNA condensation|DNA organization													biological_process											owl:Class	
GO:0071244	biolink:NamedThing	cellular response to carbon dioxide	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbon dioxide (CO2) stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-12-03T02:41:21Z					biological_process											owl:Class	
GO:0150004	biolink:NamedThing	dendritic spine origin	The part of the dendritic spine neck where the spine arises from the dendritic shaft.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0070855	biolink:NamedThing	myosin VI head/neck binding	Binding to the head/neck region of a myosin VI heavy chain.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-08-13T01:45:08Z					molecular_function											owl:Class	
GO:0070854	biolink:NamedThing	myosin VI heavy chain binding	Binding to a heavy chain of a myosin VI complex.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-08-13T01:44:05Z					molecular_function											owl:Class	
GO:0097649	biolink:NamedThing	A axonemal microtubule	A complete microtubule with 13 protofilaments that fuses with an incomplete microtubule called B tubule (containing 10 protofilaments only) to form an axonemal outer doublet. Inner and outer dynein arms, as well as the radial spoke, are attached to the A tubule.	tmpzr1t_l9r_go_relaxed.owl	A tubule							pr	2014-09-10T20:41:28Z					cellular_component											owl:Class	
GO:0038164	biolink:NamedThing	thrombopoietin receptor activity	Combining with the glycoprotein thrombopoietin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl								bf	2012-05-14T02:46:58Z					molecular_function											owl:Class	
GO:0015415	biolink:NamedThing	ATPase-coupled phosphate ion transmembrane transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + phosphate(out) = ADP + phosphate + phosphate(in).	tmpzr1t_l9r_go_relaxed.owl	phosphate porter activity|phosphate-transporting ATPase activity|ATP phosphohydrolase (phosphate-importing)|phosphate transporting ATPase activity|phosphate ABC transporter|phosphate ion transmembrane-transporting ATPase activity|ABC phosphate transporter activity				EC:7.3.2.1|RHEA:24440									molecular_function											owl:Class	
GO:1905246	biolink:NamedThing	negative regulation of aspartic-type peptidase activity	Any process that stops, prevents or reduces the frequency, rate or extent of aspartic-type peptidase activity.	tmpzr1t_l9r_go_relaxed.owl	inhibition of aspartic-type peptidase activity|downregulation of aspartic-type peptidase activity|down regulation of aspartic-type peptidase activity|pepsin inhibitor|down-regulation of aspartic-type peptidase activity							jl	2016-06-09T11:55:47Z					biological_process											owl:Class	
GO:0070819	biolink:NamedThing	menaquinone-dependent protoporphyrinogen oxidase activity	Catalysis of the reaction: protoporphyrinogen IX + menaquinone = protoporphyrin IX + reduced menaquinone.	tmpzr1t_l9r_go_relaxed.owl	protoporphyrinogen-IX:menaquinone oxidoreductase activity							mah	2009-07-20T02:46:06Z					molecular_function											owl:Class	
GO:0050979	biolink:NamedThing	magnetoreception by sensory perception of mechanical stimulus	The series of events required for an organism to receive a mechanical stimulus relating to a magnetic field, convert it to a molecular signal, and recognize and characterize the signal. A magnetic field exerts a torque on a ferromagnetic material (e.g. magnetite) or on a material with diamagnetic anisotropy; organisms that can detect this torque can use it to determine the orientation of the magnetic field.	tmpzr1t_l9r_go_relaxed.owl	magnetoreception, using mechanical stimulus|magnetoreception, sensory perception of mechanical stimulus|magnetoreception through mechanical stimulus													biological_process											owl:Class	
GO:0046705	biolink:NamedThing	CDP biosynthetic process	The chemical reactions and pathways resulting in the formation of CDP, cytidine (5'-)diphosphate.	tmpzr1t_l9r_go_relaxed.owl	CDP anabolism|CDP formation|CDP biosynthesis|CDP synthesis													biological_process											owl:Class	
GO:1903126	biolink:NamedThing	negative regulation of centriole-centriole cohesion	Any process that stops, prevents or reduces the frequency, rate or extent of centriole-centriole cohesion.	tmpzr1t_l9r_go_relaxed.owl	inhibition of centriole-centriole cohesion|down regulation of centriole-centriole cohesion|down-regulation of centriole-centriole cohesion|downregulation of centriole-centriole cohesion							als	2014-06-24T09:31:45Z					biological_process											owl:Class	
GO:0102471	biolink:NamedThing	2-hydroxynaringenin-6C-glucoside dehydratase activity	Catalysis of the reaction: 6C-glucosyl-2-hydroxynaringenin <=> isovitexin-7-olate + H2O.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-14076									molecular_function											owl:Class	
GO:0071162	biolink:NamedThing	CMG complex	A protein complex that contains the GINS complex, Cdc45p, and the heterohexameric MCM complex, and that is involved in unwinding DNA during replication.	tmpzr1t_l9r_go_relaxed.owl	unwindosome							mah	2009-11-19T11:04:13Z					cellular_component											owl:Class	
GO:0031261	biolink:NamedThing	DNA replication preinitiation complex	A protein-DNA complex assembled at eukaryotic DNA replication origins immediately prior to the initiation of DNA replication. The preinitiation complex is formed by the assembly of additional proteins onto an existing prereplicative complex. In budding yeast, the additional proteins might include Cdc45p, Sld2p, Sld3p, Dpb11p, DNA polymerases, and others; in fission yeast the GINS complex is present.	tmpzr1t_l9r_go_relaxed.owl	pre-IC													cellular_component											owl:Class	
GO:0002516	biolink:NamedThing	B cell deletion	The apoptotic death of B cells which is part of B cell tolerance induction.	tmpzr1t_l9r_go_relaxed.owl	B-lymphocyte deletion|B-cell deletion|B lymphocyte deletion													biological_process											owl:Class	
GO:0044601	biolink:NamedThing	protein denucleotidylation	The removal of a nucleotide from a protein amino acid.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-05-01T04:13:54Z					biological_process											owl:Class	
GO:0050109	biolink:NamedThing	morphine 6-dehydrogenase activity	Catalysis of the reaction: morphine + NAD(P)+ = morphinone + NAD(P)H + H+.	tmpzr1t_l9r_go_relaxed.owl	reductase, naloxone|naloxone reductase activity|morphine:NAD(P)+ 6-oxidoreductase activity				MetaCyc:MORPHINE-6-DEHYDROGENASE-RXN|EC:1.1.1.218									molecular_function											owl:Class	
GO:1902491	biolink:NamedThing	negative regulation of sperm capacitation	Any process that stops, prevents or reduces the frequency, rate or extent of sperm capacitation.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of sperm activation|down-regulation of sperm capacitation|inhibition of sperm activation|negative regulation of sperm activation|downregulation of sperm capacitation|down regulation of sperm capacitation|down regulation of sperm activation|downregulation of sperm activation|inhibition of sperm capacitation							hjd	2013-11-12T21:17:12Z					biological_process											owl:Class	
GO:1901004	biolink:NamedThing	ubiquinone-6 metabolic process	The chemical reactions and pathways involving ubiquinone-6. Ubiquinone-6 is a ubiquinone compound having a (2E,6E,10E,14E,18E)-3,7,11,15,19,23-hexamethyltetracosa-2,6,10,14,18,22-hexaen-1-yl substituent at position 2.	tmpzr1t_l9r_go_relaxed.owl	ubiquinone-6 metabolism|coenzyme Q6 metabolism|coenzyme Q6 metabolic process							bf	2012-06-15T09:59:28Z					biological_process											owl:Class	
GO:0048206	biolink:NamedThing	vesicle targeting, cis-Golgi to rough endoplasmic reticulum	The process in which vesicles are directed to specific destination membranes during transport from the cis-Golgi to the rough ER.	tmpzr1t_l9r_go_relaxed.owl	vesicle targeting, cis-Golgi to rough ER|cis-Golgi to rough endoplasmic reticulum targeting|cis-Golgi to rough ER targeting													biological_process											owl:Class	
GO:0009959	biolink:NamedThing	negative gravitropism	The orientation of plant parts away from gravity.	tmpzr1t_l9r_go_relaxed.owl	shoot gravitropism													biological_process											owl:Class	
GO:0001108	biolink:NamedThing	bacterial-type RNA polymerase holo enzyme binding	Binding to a component of the basal transcription machinery which is composed of a bacterial-type RNA polymerase core enzyme and a sigma factor, the minimal set of factors required for formation of the preinitiation complex (PIC) by a bacterial-type RNA polymerase.	tmpzr1t_l9r_go_relaxed.owl	basal bacterial-type RNA polymerase transcription machinery binding							krc	2010-11-30T04:26:04Z					molecular_function											owl:Class	
GO:0097171	biolink:NamedThing	ADP-L-glycero-beta-D-manno-heptose biosynthetic process	The chemical reactions and pathways resulting in the formation of ADP-L-glycero-beta-D-manno-heptose, an ADP-L-glycero-D-manno-heptose having beta-configuration at the anomeric centre of the heptose. ADP-L-glycero-beta-D-manno-heptose (also called ADP-L-beta-D-heptose or ADP-L-glycero-D-manno-heptose) is a nucleotide-sugar precursor of the inner core lipopolysaccharide (LPS) from D-glycero-beta-D-manno-heptose 7-phosphate.	tmpzr1t_l9r_go_relaxed.owl	ADP-L-glycero-beta-D-manno-heptose biosynthesis|ADP-L-glycero-beta-D-manno-heptose synthesis|ADP-L-glycero-beta-D-manno-heptose anabolism|ADP-L-glycero-beta-D-manno-heptose formation							pr	2011-10-03T09:15:03Z					biological_process											owl:Class	
GO:0140147	biolink:NamedThing	zinc ion export from vacuole	The directed movement of zinc ions from inside the vacuole across the vacuolar membrane and into the cytosol.	tmpzr1t_l9r_go_relaxed.owl								pg	2017-12-13T15:21:10Z					biological_process											owl:Class	
GO:1904780	biolink:NamedThing	negative regulation of protein localization to centrosome	Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to centrosome.	tmpzr1t_l9r_go_relaxed.owl	downregulation of protein localization to centrosome|downregulation of protein localisation to centrosome|down regulation of protein localisation to centrosome|down regulation of protein localization to centrosome|down-regulation of protein localization to centrosome|negative regulation of protein localisation to centrosome|down-regulation of protein localisation to centrosome|inhibition of protein localisation to centrosome|inhibition of protein localization to centrosome					An example is cdk-2 in C. elegans (UniProt ID O61847) in PMID:17115027 (inferred from mutant phenotype).		es	2015-10-30T11:54:47Z					biological_process											owl:Class	
GO:0009676	biolink:NamedThing	low-affinity sulfate:proton symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sulfate(out) + H+(out) = sulfate(in) + H+(in). In low-affinity transport the transporter is able to bind the solute only if it is present at very high concentrations.	tmpzr1t_l9r_go_relaxed.owl	low affinity sulfate:proton symporter activity|low affinity sulphate:hydrogen symporter activity|low affinity sulfate:hydrogen symporter activity													molecular_function											owl:Class	
GO:0002805	biolink:NamedThing	regulation of antimicrobial peptide biosynthetic process	Any process that modulates the frequency, rate, or extent of antimicrobial peptide biosynthesis.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0070136	biolink:NamedThing	beta-1,2-oligomannoside biosynthetic process	The chemical reactions and pathways resulting in the formation of beta-1,2-linked oligomannosides, which are found in fungal cell wall phosphopeptidomannan and phospholipomannan.	tmpzr1t_l9r_go_relaxed.owl	beta-1,2-oligomannoside synthesis|beta-1,2-oligomannoside formation|beta-1,2-oligomannoside anabolism|beta-1,2-oligomannoside biosynthesis													biological_process											owl:Class	
GO:0046354	biolink:NamedThing	mannan biosynthetic process	The chemical reactions and pathways resulting in the formation of mannan, the main hemicellulose of soft (coniferous) wood, made up of D-mannose, D-glucose and D-galactose.	tmpzr1t_l9r_go_relaxed.owl	mannan formation|mannan anabolism|mannan synthesis|mannan biosynthesis													biological_process											owl:Class	
GO:0052784	biolink:NamedThing	reuteran biosynthetic process	The chemical reactions and pathways resulting in the formation of reuteran, a soluble glucan polymer with mainly alpha-(1->4) glycosidic linkages and significant amounts of alpha-(1->6) and alpha-(1->4,6) glucosidic linkages.	tmpzr1t_l9r_go_relaxed.owl	reuteransucrase-mediated reuteran biosynthesis							ai	2011-10-04T09:20:35Z					biological_process											owl:Class	
GO:1905467	biolink:NamedThing	positive regulation of G-quadruplex DNA unwinding	Any process that activates or increases the frequency, rate or extent of G-quadruplex DNA unwinding.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of G-quadruplex DNA unwinding|activation of G-quadruplex DNA unwinding|up regulation of G-quadruplex DNA unwinding|upregulation of G-quadruplex DNA unwinding							ans	2016-09-19T12:16:01Z					biological_process											owl:Class	
GO:0071985	biolink:NamedThing	multivesicular body sorting pathway	A vesicle-mediated transport process in which transmembrane proteins are ubiquitylated to facilitate their entry into luminal vesicles of multivesicular bodies (MVBs); upon subsequent fusion of MVBs with lysosomes or vacuoles, the cargo proteins are degraded.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-10-22T12:04:16Z					biological_process											owl:Class	
GO:0051000	biolink:NamedThing	positive regulation of nitric-oxide synthase activity	Any process that activates or increases the activity of the enzyme nitric-oxide synthase.	tmpzr1t_l9r_go_relaxed.owl	stimulation of nitric-oxide synthase activity|activation of nitric-oxide synthase activity|nitric-oxide synthase activator|upregulation of nitric-oxide synthase activity|up-regulation of nitric-oxide synthase activity|up regulation of nitric-oxide synthase activity|NOS activator|positive regulation of NOS activity													biological_process											owl:Class	
GO:0002209	biolink:NamedThing	behavioral defense response	A behavioral response seeking to protect an organism from an a perceived external threat to that organism.	tmpzr1t_l9r_go_relaxed.owl	behavioural defense response													biological_process											owl:Class	
GO:0005158	biolink:NamedThing	insulin receptor binding	Binding to an insulin receptor.	tmpzr1t_l9r_go_relaxed.owl	insulin receptor ligand													molecular_function											owl:Class	
GO:0050683	biolink:NamedThing	AF-1 domain binding	Binding to an AF-1 protein domain, a ligand-independent transactivation domain which is required for the full transcriptional activity of the receptor.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1900932	biolink:NamedThing	regulation of nonadec-1-ene metabolic process	Any process that modulates the frequency, rate or extent of nonadec-1-ene metabolic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of nonadec-1-ene metabolism							tt	2012-06-14T03:11:28Z					biological_process											owl:Class	
GO:0008721	biolink:NamedThing	D-serine ammonia-lyase activity	Catalysis of the reaction: D-serine = pyruvate + NH3.	tmpzr1t_l9r_go_relaxed.owl	D-hydroxyaminoacid dehydratase activity|D-serine hydrolase activity|D-serine hydro-lyase (deaminating) activity|D-hydroxy amino acid dehydratase activity|D-serine dehydrase activity|D-serine dehydration activity|D-serine dehydratase (deaminating) activity|D-serine ammonia-lyase (pyruvate-forming)|D-serine dehydratase activity|D-serine deaminase activity				Reactome:R-HSA-9014741|Reactome:R-HSA-9034539|RHEA:13977|MetaCyc:DSERDEAM-RXN|EC:4.3.1.18	Note that this function was formerly EC:4.3.1.14.								molecular_function											owl:Class	
GO:0043881	biolink:NamedThing	mesaconyl-CoA hydratase activity	Catalysis of the hydration of mesaconyl-CoA to beta-methylmalyl-CoA.	tmpzr1t_l9r_go_relaxed.owl	mch|beta-methylmalyl-CoA dehydratase activity|mesaconyl-coenzyme A hydratase activity					This function is part of an alternate glyoxylate cycle for acetate assimilation.								molecular_function											owl:Class	
GO:0051456	biolink:NamedThing	attachment of spindle microtubules to kinetochore involved in meiotic sister chromatid segregation	The process in which spindle microtubules become physically associated with the proteins making up the kinetochore complex during meiosis II. During meiosis II sister kinetochores are situated facing opposite spindle poles and bipolar attachment of the sister chromosomes to the spindle occurs.	tmpzr1t_l9r_go_relaxed.owl	meiotic bipolar attachment|attachment of spindle microtubules to kinetochore involved in meiosis II|attachment of spindle microtubules to kinetochore during meiosis II													biological_process											owl:Class	
GO:1990984	biolink:NamedThing	tRNA demethylase activity	Catalysis of the removal of a methyl group from one or more positions within a tRNA molecule.	tmpzr1t_l9r_go_relaxed.owl								sp	2016-10-28T08:38:14Z					molecular_function											owl:Class	
GO:0016460	biolink:NamedThing	myosin II complex	A myosin complex containing two class II myosin heavy chains, two myosin essential light chains and two myosin regulatory light chains. Also known as classical myosin or conventional myosin, the myosin II class includes the major muscle myosin of vertebrate and invertebrate muscle, and is characterized by alpha-helical coiled coil tails that self assemble to form a variety of filament structures.	tmpzr1t_l9r_go_relaxed.owl	conventional myosin													cellular_component											owl:Class	
GO:0033229	biolink:NamedThing	cysteine transmembrane transporter activity	Enables the transfer of cysteine from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/17289			RHEA:32795									molecular_function											owl:Class	
GO:0030265	biolink:NamedThing	phospholipase C-activating rhodopsin mediated signaling pathway	The series of molecular signals generated as a consequence of a rhodopsin molecule being activated by a photon, where the pathway proceeds with activation of phospholipase C (PLC) and a subsequent release of inositol trisphosphate (IP3) and diacylglycerol (DAG).	tmpzr1t_l9r_go_relaxed.owl	rhodopsin mediated G-protein signaling, coupled to IP3 second messenger|rhodopsin mediated G protein signalling, coupled to IP3 second messenger|phospholipase C-activating rhodopsin mediated G-protein coupled receptor signaling pathway|rhodopsin mediated G-protein signalling, coupled to IP3 second messenger|PLC-activating rhodopsin mediated signaling pathway|rhodopsin mediated G protein signaling, coupled to IP3 second messenger													biological_process											owl:Class	
GO:0048776	biolink:NamedThing	negative regulation of leucophore differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of leucophore differentiation.	tmpzr1t_l9r_go_relaxed.owl	inhibition of leucophore differentiation|down-regulation of leucophore differentiation|down regulation of leucophore differentiation|downregulation of leucophore differentiation													biological_process											owl:Class	
GO:0071744	biolink:NamedThing	IgE B cell receptor complex	An IgE immunoglobulin complex that is present in the plasma membrane of B cells and is composed of two identical immunoglobulin heavy chains of the IgE isotype and two identical immunoglobulin light chains and a signaling subunit, a heterodimer of the Ig-alpha and Ig-beta proteins.	tmpzr1t_l9r_go_relaxed.owl	membrane-bound IgE|surface IgE					Note that an IgE immunoglobulin complex has the function of antigen binding if a suitable antigen is available.		mah	2010-03-24T01:44:53Z					cellular_component											owl:Class	
GO:0075328	biolink:NamedThing	formation of arbuscule for nutrient acquisition	The assembly of an arbuscule, a fine, tree-like hyphal symbiont structure projected into the host cell for the purpose of obtaining nutrients. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	formation by symbiont of arbuscule for nutrient acquisition from host	https://github.com/geneontology/go-ontology/issues/20305				Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products from the symbiont involved in this process.								biological_process											owl:Class	
GO:0098583	biolink:NamedThing	learned vocalization behavior	A vocalization behavior that is the result of learning.	tmpzr1t_l9r_go_relaxed.owl						Examples include human speech and learned bird song.		dos	2014-01-24T12:48:57Z					biological_process											owl:Class	
GO:0098598	biolink:NamedThing	learned vocalization behavior or vocal learning	Vocalisation behavior that is the result of learning, or the process by which new vocalizations are learned.	tmpzr1t_l9r_go_relaxed.owl						This grouping term is necessary because, in the absence of conditional mutations, it is not possible to use phenotypic evidence to distinguish an effect on vocal learning from an effect on learned vocalisation behavior.		dos	2014-04-10T11:34:33Z					biological_process											owl:Class	
GO:0032187	biolink:NamedThing	actomyosin contractile ring localization	The process in which a contractile ring is assembled and/or maintained in a specific location, in the context of cytokinesis that takes place as part of a cell cycle.	tmpzr1t_l9r_go_relaxed.owl	contractile ring localisation involved in cell cycle cytokinesis|contractile ring localization involved in cell cycle cytokinesis													biological_process											owl:Class	
GO:0036214	biolink:NamedThing	contractile ring localization	The process in which a contractile ring is assembled and/or maintained in a specific location.	tmpzr1t_l9r_go_relaxed.owl						This term can be used to annotate localization of either bacterial or fungal contractile rings.		bf	2012-04-26T02:58:50Z					biological_process											owl:Class	
GO:0099549	biolink:NamedThing	trans-synaptic signaling by carbon monoxide	Cell-cell signaling between presynapse and postsynapse mediated by carbon monoxide.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0002041	biolink:NamedThing	intussusceptive angiogenesis	The formation of new blood vessels as a result of the insertion and extension of lumenal tissue pillars.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1900397	biolink:NamedThing	regulation of pyrimidine nucleotide biosynthetic process	Any process that modulates the frequency, rate or extent of pyrimidine nucleotide biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of pyrimidine nucleotide synthesis|regulation of pyrimidine nucleotide anabolism|regulation of pyrimidine nucleotide formation|regulation of pyrimidine nucleotide biosynthesis							jh	2012-04-19T01:05:31Z					biological_process											owl:Class	
GO:0043507	biolink:NamedThing	positive regulation of JUN kinase activity	Any process that activates or increases the frequency, rate or extent of JUN kinase activity.	tmpzr1t_l9r_go_relaxed.owl	upregulation of JNK activity|up regulation of JNK activity|positive regulation of JUNK activity|up-regulation of JNK activity|stimulation of JNK activity													biological_process											owl:Class	
GO:1905937	biolink:NamedThing	negative regulation of germ cell proliferation	Any process that stops, prevents or reduces the frequency, rate or extent of germ cell proliferation.	tmpzr1t_l9r_go_relaxed.owl	downregulation of germ cell proliferation|down-regulation of germ cell proliferation|inhibition of germ cell proliferation|down regulation of germ cell proliferation							hbye	2017-02-09T14:51:41Z					biological_process											owl:Class	
GO:1990470	biolink:NamedThing	piRNA cluster binding	Binding to piRNA clusters, double-stranded DNA regions that give rise to PIWI-interacting RNAs (piRNAs).	tmpzr1t_l9r_go_relaxed.owl						An example of this is rhi in Drosophila melanogaster (Q7JXA8) in PMID:24906153 (inferred from direct assay).		bhm	2014-08-29T14:23:38Z					molecular_function											owl:Class	
GO:0090053	biolink:NamedThing	positive regulation of pericentric heterochromatin assembly	Any process that increases the frequency, rate or extent of chromatin silencing at the centromere. Chromatin silencing at the centromere is the repression of transcription of centromeric DNA by altering the structure of chromatin.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of chromatin silencing at centromere	https://github.com/geneontology/go-ontology/issues/19112						tb	2009-08-07T10:49:40Z					biological_process											owl:Class	
GO:0070442	biolink:NamedThing	integrin alphaIIb-beta3 complex	An integrin complex that comprises one alphaIIb subunit and one beta3 subunit.	tmpzr1t_l9r_go_relaxed.owl	alphaIIb-beta3 integrin complex|ITGA2B-ITGB3 complex													cellular_component											owl:Class	
GO:0072461	biolink:NamedThing	response to meiotic recombination checkpoint signaling	A process that occurs in response to signals generated as a result of meiotic recombination checkpoint signaling.	tmpzr1t_l9r_go_relaxed.owl	meiotic recombination checkpoint effector process|response to signal involved in meiotic recombination checkpoint							mah	2010-12-09T11:37:01Z					biological_process											owl:Class	
GO:0140021	biolink:NamedThing	mitochondrial ADP transmembrane transport	The process in which ADP is transported across a mitochondrial membrane, into or out of the mitochondrion.	tmpzr1t_l9r_go_relaxed.owl								pg	2017-04-10T15:14:34Z					biological_process											owl:Class	
GO:0106225	biolink:NamedThing	peptidyl-lysine 2-hydroxyisobutyrylation	The 2-hydroxyisobutyrylation of a lysine residue in a protein.	tmpzr1t_l9r_go_relaxed.owl								hjd	2019-10-17T18:51:15Z					biological_process											owl:Class	
GO:0044675	biolink:NamedThing	formyl-methanofuran dehydrogenase (tungsten enzyme) complex	A protein complex consisting of four polypeptides which also contains tungsten, a molybdopterin guanine dinucleotide, and iron-sulfur clusters. This protein complex catalyzes the reversible conversion of CO2 and methanofuran to formylmethanofuran during methanogenesis.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-08-09T10:54:49Z					cellular_component											owl:Class	
GO:0072730	biolink:NamedThing	response to papulacandin B	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a papulacandin B stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2012-05-31T11:30:32Z					biological_process											owl:Class	
GO:0046408	biolink:NamedThing	chlorophyll synthetase activity	Catalysis of the reaction: chlorophyllide a + 2 H(+) + phytyl diphosphate = chlorophyll a + diphosphate.	tmpzr1t_l9r_go_relaxed.owl	chlorophyll synthase activity|chlorophyllide-a:phytyl-diphosphate phytyltransferase activity				RHEA:17317|MetaCyc:RXN1F-66|EC:2.5.1.62|KEGG_REACTION:R06284							GO:0043787		molecular_function											owl:Class	
GO:0048406	biolink:NamedThing	nerve growth factor binding	Binding to nerve growth factor (NGF).	tmpzr1t_l9r_go_relaxed.owl	neurotrophin TRKA receptor activity|NGF binding|beta-nerve growth factor binding													molecular_function											owl:Class	
GO:0043121	biolink:NamedThing	neurotrophin binding	Binding to a neurotrophin, any of a family of growth factors that prevent apoptosis in neurons and promote nerve growth.	tmpzr1t_l9r_go_relaxed.owl	neurotrophin TRKB receptor activity|neurotrophin TRKA receptor activity|NT-4/5 binding|NT4 binding|neurotrophin TRK receptor activity|NT3 binding|neurotrophin 3 binding|NT-4 binding|NT5 binding|neurotrophin-3 binding|NT-3 binding|neurotrophin 4/5 binding|neurotrophic factor binding|NT-5 binding|neurotrophin-4/5 binding|NT 4/5 binding|neurotrophin TRKC receptor activity					Note that mammalian NT-5 was initially named differently from amphibian NT-4 because of sequence differences, but the two genes were later shown to be functionally equivalent [SF:919858].						GO:0048405|GO:0048404		molecular_function											owl:Class	
GO:0002473	biolink:NamedThing	non-professional antigen presenting cell antigen processing and presentation	The process in which a non-professional antigen presenting cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex. Non-professional antigen presenting cells include all cell types but dendritic cells, B cells, T cells, monocytes, macrophages, and neutrophils.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0009997	biolink:NamedThing	negative regulation of cardioblast cell fate specification	Any process that restricts, stops or prevents a cell from specifying into a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.	tmpzr1t_l9r_go_relaxed.owl	inhibition of cardioblast cell fate specification|down regulation of cardioblast cell fate specification|suppression of cardioblast cell fate|down-regulation of cardioblast cell fate specification|downregulation of cardioblast cell fate specification											GO:0042687		biological_process											owl:Class	
GO:0048885	biolink:NamedThing	neuromast deposition	The process in which a migrating neuromast primordium deposits clusters of undifferentiated cells (proneuromasts) along its migratory path in a developing lateral line.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0062045	biolink:NamedThing	L-lysine alpha-aminotransferase	Catalysis of the reaction: L-lysine + pyruvate= epsilon-amino-alpha-ketocaproic acid (KAC) + alanine.	tmpzr1t_l9r_go_relaxed.owl								dph	2018-05-11T12:13:57Z					molecular_function											owl:Class	
GO:0099171	biolink:NamedThing	presynaptic modulation of chemical synaptic transmission	Any process, acting in the presynapse that results in modulation of chemical synaptic transmission.	tmpzr1t_l9r_go_relaxed.owl								dos	2017-09-11T17:09:31Z					biological_process											owl:Class	
GO:0046221	biolink:NamedThing	pyridine catabolic process	The chemical reactions and pathways resulting in the breakdown of pyridine, a nitrogenous base (C5H5N) obtained from the distillation of bone oil or coal tar, and by the decomposition of certain alkaloids, as a colorless liquid with a peculiar pungent odor.	tmpzr1t_l9r_go_relaxed.owl	pyridine degradation|pyridine breakdown|pyridine catabolism													biological_process											owl:Class	
GO:0004386	biolink:NamedThing	helicase activity	Catalysis of the reaction: ATP + H2O = ADP + phosphate, to drive the unwinding of a DNA or RNA helix.	tmpzr1t_l9r_go_relaxed.owl	ATP-dependent helicase activity	https://github.com/geneontology/go-ontology/issues/21393			Reactome:R-HSA-169468|Reactome:R-HSA-5686410|Reactome:R-HSA-169461|Reactome:R-HSA-5690996	Note that most helicases catalyze processive duplex unwinding.						GO:0008026		molecular_function											owl:Class	
GO:0036415	biolink:NamedThing	regulation of tRNA stability	Any process that modulates the propensity of transfer RNA (tRNA) molecules to degradation. Includes processes that both stabilize and destabilize tRNAs.	tmpzr1t_l9r_go_relaxed.owl								bf	2013-08-22T15:22:13Z					biological_process											owl:Class	
GO:0002873	biolink:NamedThing	positive regulation of natural killer cell tolerance induction	Any process that activates or increases the frequency, rate, or extent of natural killer cell tolerance induction.	tmpzr1t_l9r_go_relaxed.owl	upregulation of natural killer cell tolerance induction|stimulation of natural killer cell tolerance induction|up-regulation of natural killer cell tolerance induction|positive regulation of NK cell tolerance induction|up regulation of natural killer cell tolerance induction|activation of natural killer cell tolerance induction													biological_process											owl:Class	
GO:1900305	biolink:NamedThing	positive regulation of laminaritriose transport	Any process that activates or increases the frequency, rate or extent of laminaritriose transport.	tmpzr1t_l9r_go_relaxed.owl	up regulation of laminaritriose transport|up-regulation of laminaritriose transport|activation of laminaritriose transport|upregulation of laminaritriose transport							tt	2012-04-05T07:58:06Z					biological_process											owl:Class	
GO:0045324	biolink:NamedThing	late endosome to vacuole transport	The directed movement of substances from late endosomes to the vacuole. In yeast, after transport to the prevacuolar compartment, endocytic content is delivered to the late endosome and on to the vacuole. This pathway is analogous to endosome to lysosome transport.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0005030	biolink:NamedThing	neurotrophin receptor activity	Combining with a neurotrophin, any of a family of growth factors that prevent apoptosis in neurons and promote nerve growth, and transmitting the signal to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0140440	biolink:NamedThing	protein-cysteine S-oleoyltransferase activity	Catalysis of the transfer of an oleoyl (systematic name, (9Z)-octadecenoyl) group to a sulfur atom on the cysteine of a protein molecule, in the reaction: (9Z)-octadecenoyl-CoA + L-cysteinyl-[protein] = CoA + S-(9Z-octadecenoyl)-L-cysteinyl-[protein].	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/18882			RHEA:59744			pg	2020-03-11T09:56:11Z					molecular_function											owl:Class	
GO:1990713	biolink:NamedThing	survivin complex	A protein complex that negatively regulates apoptotic processes. In human, this anti-apoptotic complex is a homodimer of BIRC5 (survivin) and provides one survivin molecule to the chromosomal passenger complex (CPC).	tmpzr1t_l9r_go_relaxed.owl	Baculoviral IAP repeat-containing protein 5 complex|survivin homodimer complex					An example of this is BIRC5 in human (UniProt symbol O15392) in PMID:10949038 (inferred from physical interaction).		bhm	2015-03-26T14:21:46Z					cellular_component											owl:Class	
GO:0010187	biolink:NamedThing	negative regulation of seed germination	Any process that stops, prevents, or reduces the frequency, rate or extent of seed germination.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of seed germination|inhibition of seed germination|down regulation of seed germination|downregulation of seed germination													biological_process											owl:Class	
GO:0005119	biolink:NamedThing	smoothened binding	Binding to a smoothened (smo) protein, which interacts with patched to transmit hedgehog signals.	tmpzr1t_l9r_go_relaxed.owl	smo ligand|smoothened ligand|smo binding													molecular_function											owl:Class	
GO:1901948	biolink:NamedThing	5alpha,9alpha,10beta-labda-8(20),13-dien-15-yl diphosphate catabolic process	The chemical reactions and pathways resulting in the breakdown of 5alpha,9alpha,10beta-labda-8(20),13-dien-15-yl diphosphate.	tmpzr1t_l9r_go_relaxed.owl	5alpha,9alpha,10beta-labda-8(20),13-dien-15-yl diphosphate catabolism|5alpha,9alpha,10beta-labda-8(20),13-dien-15-yl diphosphate breakdown|5alpha,9alpha,10beta-labda-8(20),13-dien-15-yl diphosphate degradation							ms	2013-02-18T15:50:45Z					biological_process											owl:Class	
GO:0050450	biolink:NamedThing	citrate (Re)-synthase activity	Catalysis of the reaction: acetyl-CoA + H2O + oxaloacetate = citrate + CoA, where the acetyl group is added to the re-face of oxaloacetate; acetyl-CoA provides the two carbon atoms of the pro-R carboxymethyl group.	tmpzr1t_l9r_go_relaxed.owl	citrate oxaloacetate-lyase [(pro-3R)-CH2COO-rightacetyl-CoA]|acetyl-CoA:oxaloacetate C-acetyltransferase [thioester-hydrolysing, (pro-R)-carboxymethyl-forming]|Re-citrate-synthase activity|(R)-citrate synthase activity|citrate oxaloacetate-lyase ((pro-3R)-CH(2)COO(-)->acetyl-CoA) activity				EC:2.3.3.3|MetaCyc:CITRATE-RE-SYNTHASE-RXN									molecular_function											owl:Class	
GO:0036440	biolink:NamedThing	citrate synthase activity	Catalysis of the reaction: acetyl-CoA + H2O + oxaloacetate = citrate + CoA.	tmpzr1t_l9r_go_relaxed.owl					KEGG_REACTION:R00351|RHEA:16845			bf	2013-09-30T16:21:50Z					molecular_function											owl:Class	
GO:0030310	biolink:NamedThing	poly-N-acetyllactosamine catabolic process	The chemical reactions and pathways resulting in the breakdown of poly-N-acetyllactosamine, a carbohydrate composed of N-acetyllactosamine repeats (Gal-beta-1,4-GlcNAc-beta-1,3)n.	tmpzr1t_l9r_go_relaxed.owl	poly-N-acetyllactosamine degradation|poly-N-acetyllactosamine breakdown|poly-N-acetyllactosamine catabolism													biological_process											owl:Class	
GO:0035342	biolink:NamedThing	positive regulation of inosine transport	Any process that activates or increases the frequency, rate or extent of the directed movement of inosine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of hypoxanthine riboside transport							bf	2010-03-04T10:05:03Z					biological_process											owl:Class	
GO:0035341	biolink:NamedThing	regulation of inosine transport	Any process that modulates the frequency, rate or extent of the directed movement of inosine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	regulation of hypoxanthine riboside transport							bf	2010-03-04T10:03:51Z					biological_process											owl:Class	
GO:1905402	biolink:NamedThing	regulation of activated CD8-positive, alpha-beta T cell apoptotic process	Any process that modulates the frequency, rate or extent of activated CD8-positive, alpha-beta T cell apoptotic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of activated CD8-positive, alpha-beta T-lymphocyte apoptotic process|regulation of activated CD8-positive, alpha-beta T lymphocyte apoptosis|regulation of activated CD8-positive, alpha-beta T-lymphocyte apoptosis|regulation of activated CD8-positive, alpha-beta T-cell apoptotic process|regulation of activated CD8-positive, alpha-beta T-cell apoptosis|regulation of activated CD8-positive, alpha-beta T cell apoptosis|regulation of activated CD8-positive, alpha-beta T lymphocyte apoptotic process							pga	2016-08-25T09:13:56Z					biological_process											owl:Class	
GO:0033227	biolink:NamedThing	dsRNA transport	The directed movement of dsRNA, double-stranded ribonucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0052645	biolink:NamedThing	F420-0 metabolic process	The chemical reactions and pathways involving F420-0 (5-O-{[(1S)-1-carboxyethoxy](hydroxy)phosphoryl}-1-deoxy-1-(8-hydroxy-2,4-dioxo-2H-pyrimido[4,5-b]quinolin-10(4H)-yl)-D-ribitol), the fragment of coenzyme F420 remaining after formal hydrolytic removal of all of the glutamate residues.	tmpzr1t_l9r_go_relaxed.owl	coenzyme F420-0 metabolic process|F420-0 metabolism|coenzyme F420-0 metabolism|F(420)-0 metabolic process							ai	2010-09-22T04:11:38Z					biological_process											owl:Class	
GO:0008734	biolink:NamedThing	L-aspartate oxidase activity	Catalysis of the reaction: L-aspartate + O2 = iminosuccinate + hydrogen peroxide.	tmpzr1t_l9r_go_relaxed.owl	L-aspartate:oxygen oxidoreductase				EC:1.4.3.16|MetaCyc:L-ASPARTATE-OXID-RXN|RHEA:25876|MetaCyc:RXN-9772									molecular_function											owl:Class	
GO:0015922	biolink:NamedThing	aspartate oxidase activity	Catalysis of the reaction: aspartate + O2 = iminosuccinate + hydrogen peroxide.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0102577	biolink:NamedThing	3-oxo-palmitate decarboxylase activity	Catalysis of the reaction: 3-oxopalmitic acid + H+ = 2-pentadecanone + carbon dioxide.	tmpzr1t_l9r_go_relaxed.owl					EC:4.1.1.56|MetaCyc:RXN-15283									molecular_function											owl:Class	
GO:0033359	biolink:NamedThing	lysine biosynthetic process via diaminopimelate and N-succinyl-2-amino-6-ketopimelate	The chemical reactions and pathways resulting in the formation of lysine, via the intermediates diaminopimelate and N-succinyl-2-amino-6-ketopimelate; in this pathway tetrahydrodipicolinate is converted to meso-diaminopimelate in four enzymatic steps.	tmpzr1t_l9r_go_relaxed.owl	lysine biosynthesis via diaminopimelic acid and N-succinyl-2-amino-6-ketopimelate|lysine biosynthetic process via diaminopimelic acid and N-succinyl-2-amino-6-ketopimelate|lysine anabolism via diaminopimelate and N-succinyl-2-amino-6-ketopimelate|lysine formation via diaminopimelate and N-succinyl-2-amino-6-ketopimelate|lysine synthesis via diaminopimelate and N-succinyl-2-amino-6-ketopimelate				MetaCyc:DAPLYSINESYN-PWY									biological_process											owl:Class	
GO:0090643	biolink:NamedThing	inflorescence phyllotactic patterning	The radial pattern formation process that results in the formation of flowers around a central axis in an inflorescence meristem.	tmpzr1t_l9r_go_relaxed.owl								tb	2015-05-05T14:25:09Z					biological_process											owl:Class	
GO:0060771	biolink:NamedThing	phyllotactic patterning	The radial pattern formation process that results in the formation of plant organs (leaves or leaf-like structures) or flower primordia around a central axis.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-07-25T06:20:33Z					biological_process											owl:Class	
GO:0035607	biolink:NamedThing	fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development	The series of molecular signals generated as a consequence of a fibroblast growth factor-type receptor binding to one of its physiological ligands, which contributes to the progression of the orbitofrontal cortex over time from its initial formation until its mature state.	tmpzr1t_l9r_go_relaxed.owl	FGF receptor signaling pathway involved in orbitofrontal cortex development|fibroblast growth factor receptor signalling pathway involved in orbitofrontal cortex development|FGFR signaling pathway involved in orbitofrontal cortex development							bf	2010-11-16T11:30:19Z					biological_process											owl:Class	
GO:0010462	biolink:NamedThing	regulation of light-activated voltage-gated calcium channel activity	Any process that modulates the frequency, rate or extent of light-activated voltage-gated calcium channel activity.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0071954	biolink:NamedThing	chemokine (C-C motif) ligand 11 production	The appearance of chemokine (C-C motif) ligand 11 (CCL11, also known as eotaxin-1) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	tmpzr1t_l9r_go_relaxed.owl	CCL11 production|CCL-11 production|eotaxin production|eotaxin-1 production|C-C motif chemokine 11 production							mah	2010-10-08T12:10:34Z					biological_process											owl:Class	
GO:0031631	biolink:NamedThing	negative regulation of synaptic vesicle fusion to presynaptic active zone membrane	Any process that stops, prevents, or reduces the frequency, rate or extent of synaptic vesicle fusion to the presynaptic membrane.	tmpzr1t_l9r_go_relaxed.owl	downregulation of synaptic vesicle fusion to presynaptic active zone membrane|negative regulation of synaptic vesicle fusion to presynaptic membrane|down regulation of synaptic vesicle fusion to presynaptic active zone membrane|down-regulation of synaptic vesicle fusion to presynaptic active zone membrane|negative regulation of synaptic vesicle fusion to pre-synaptic membrane|negative regulation of synaptic vesicle fusion to pre-synaptic active zone membrane|inhibition of synaptic vesicle fusion to presynaptic membrane|down-regulation of synaptic vesicle fusion to presynaptic membrane|down regulation of synaptic vesicle fusion to presynaptic membrane|downregulation of synaptic vesicle fusion to presynaptic membrane													biological_process											owl:Class	
GO:1901633	biolink:NamedThing	negative regulation of synaptic vesicle membrane organization	Any process that stops, prevents or reduces the frequency, rate or extent of synaptic vesicle membrane organization.	tmpzr1t_l9r_go_relaxed.owl	inhibition of synaptic vesicle membrane organisation|inhibition of synaptic vesicle membrane organization|down regulation of synaptic vesicle membrane organisation|down regulation of SLMV biogenesis|downregulation of synaptic vesicle membrane organization and biogenesis|down-regulation of synaptic vesicle membrane organization and biogenesis|inhibition of synaptic vesicle membrane organization and biogenesis|down-regulation of synaptic vesicle membrane organization|negative regulation of synaptic vesicle membrane organisation|inhibition of SLMV biogenesis|down-regulation of synaptic vesicle membrane organisation|downregulation of synaptic vesicle membrane organisation|negative regulation of synaptic vesicle membrane organization and biogenesis|negative regulation of SLMV biogenesis|down-regulation of SLMV biogenesis|down regulation of synaptic vesicle membrane organization|downregulation of synaptic vesicle membrane organization|downregulation of SLMV biogenesis|down regulation of synaptic vesicle membrane organization and biogenesis							ans	2012-11-15T11:40:55Z					biological_process											owl:Class	
GO:0033581	biolink:NamedThing	protein galactosylation in Golgi	The addition of a galactose unit to a protein amino acid in any compartment of the Golgi apparatus.	tmpzr1t_l9r_go_relaxed.owl	protein amino acid galactosylation in Golgi													biological_process											owl:Class	
GO:0033578	biolink:NamedThing	protein glycosylation in Golgi	The addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid in any compartment of the Golgi apparatus.	tmpzr1t_l9r_go_relaxed.owl	terminal glycosylation|protein amino acid glycosylation in Golgi													biological_process											owl:Class	
GO:0103007	biolink:NamedThing	indole-3-acetate carboxyl methyltransferase activity	Catalysis of the reaction: indole-3-acetate + S-adenosyl-L-methionine  <=> methyl (indol-3-yl)acetate + S-adenosyl-L-homocysteine.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-9825|RHEA:36131|EC:2.1.1.278									molecular_function											owl:Class	
GO:0032671	biolink:NamedThing	regulation of interleukin-27 production	Any process that modulates the frequency, rate, or extent of interleukin-27 production.	tmpzr1t_l9r_go_relaxed.owl	regulation of interleukin-27 synthesis|regulation of IL-27 production|regulation of interleukin-27 formation|regulation of interleukin-27 biosynthetic process											GO:0045531		biological_process											owl:Class	
GO:0032309	biolink:NamedThing	icosanoid secretion	The controlled release of icosanoids, any of a group of C20 polyunsaturated fatty acids from a cell or a tissue.	tmpzr1t_l9r_go_relaxed.owl	eicosanoid secretion													biological_process											owl:Class	
GO:0042279	biolink:NamedThing	nitrite reductase (cytochrome, ammonia-forming) activity	Catalysis of the reaction: NH3 + 2 H2O + 6 ferricytochrome c = nitrite + 6 ferrocytochrome c + 7 H+.	tmpzr1t_l9r_go_relaxed.owl	multiheme nitrite reductase activity|cytochrome c552 activity|ammonia:ferricytochrome-c oxidoreductase activity|cytochrome c nitrite reductase activity|nitrite reductase (cytochrome; ammonia-forming)				EC:1.7.2.2|MetaCyc:1.7.2.2-RXN|Wikipedia:Cytochrome_c_nitrite_reductase|RHEA:13089									molecular_function											owl:Class	
GO:0031116	biolink:NamedThing	positive regulation of microtubule polymerization	Any process that activates or increases the frequency, rate or extent of microtubule polymerization.	tmpzr1t_l9r_go_relaxed.owl	up regulation of microtubule polymerization|stimulation of microtubule polymerization|activation of microtubule polymerization|up-regulation of microtubule polymerization|upregulation of microtubule polymerization													biological_process											owl:Class	
GO:0031112	biolink:NamedThing	positive regulation of microtubule polymerization or depolymerization	Any process that activates or increases the frequency, rate or extent of microtubule polymerization or depolymerization.	tmpzr1t_l9r_go_relaxed.owl	stimulation of microtubule polymerization or depolymerization|upregulation of microtubule polymerization or depolymerization|up regulation of microtubule polymerization or depolymerization|up-regulation of microtubule polymerization or depolymerization|activation of microtubule polymerization or depolymerization													biological_process											owl:Class	
GO:0050601	biolink:NamedThing	myristoyl-CoA 11-(Z) desaturase activity	Catalysis of the reaction: myristoyl-CoA + NAD(P)H + H+ + O2 = (Z)-11-tetradecenoyl-CoA + NAD(P)+ + 2 H2O.	tmpzr1t_l9r_go_relaxed.owl	fatty acid delta(11)-desaturase|delta(11)-palmitoyl-CoA desaturase|Z/E11-desaturase|delta(11)-fatty-acid desaturase|delta(11) desaturase				EC:1.14.19.5|MetaCyc:1.14.99.32-RXN|RHEA:25852									molecular_function											owl:Class	
GO:1903587	biolink:NamedThing	regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis	Any process that modulates the frequency, rate or extent of blood vessel endothelial cell proliferation involved in sprouting angiogenesis.	tmpzr1t_l9r_go_relaxed.owl	regulation of blood vessel endothelial cell proliferation during sprouting angiogenesis							pga	2014-11-04T11:39:31Z					biological_process											owl:Class	
GO:1904783	biolink:NamedThing	positive regulation of NMDA glutamate receptor activity	Any process that activates or increases the frequency, rate or extent of NMDA glutamate receptor activity.	tmpzr1t_l9r_go_relaxed.owl	activation of N-methyl-D-aspartate selective glutamate receptor activity|activation of NMDA receptor|up-regulation of N-methyl-D-aspartate selective glutamate receptor activity|activation of NMDA glutamate receptor activity|upregulation of NMDA glutamate receptor activity|upregulation of N-methyl-D-aspartate selective glutamate receptor activity|upregulation of NMDA receptor|up-regulation of NMDA glutamate receptor activity|up regulation of NMDA receptor|positive regulation of N-methyl-D-aspartate selective glutamate receptor activity|up-regulation of NMDA receptor|up regulation of NMDA glutamate receptor activity|up regulation of N-methyl-D-aspartate selective glutamate receptor activity|positive regulation of NMDA receptor							mr	2015-10-30T19:39:37Z					biological_process											owl:Class	
GO:0031203	biolink:NamedThing	posttranslational protein targeting to membrane, docking	The process in which the signal sequence of a translated protein binds to and forms a complex with the Sec complex.	tmpzr1t_l9r_go_relaxed.owl	Sec-translated protein complex assembly|protein docking during posttranslational protein targeting to membrane|posttranslational protein membrane targeting, docking													biological_process											owl:Class	
GO:0009582	biolink:NamedThing	detection of abiotic stimulus	The series of events in which an (non-living) abiotic stimulus is received by a cell and converted into a molecular signal.	tmpzr1t_l9r_go_relaxed.owl	perception of abiotic stimulus													biological_process											owl:Class	
GO:0002618	biolink:NamedThing	positive regulation of macrophage antigen processing and presentation	Any process that activates or increases the frequency, rate, or extent of macrophage antigen processing and presentation.	tmpzr1t_l9r_go_relaxed.owl	upregulation of macrophage antigen processing and presentation|up regulation of macrophage antigen processing and presentation|stimulation of macrophage antigen processing and presentation|up-regulation of macrophage antigen processing and presentation|activation of macrophage antigen processing and presentation													biological_process											owl:Class	
GO:0046197	biolink:NamedThing	orcinol biosynthetic process	The chemical reactions and pathways resulting in the formation of orcinol (5-methyl-1,3-benzenediol), an aromatic compound derived from the fermentation of lichen and synthesized by some higher plants.	tmpzr1t_l9r_go_relaxed.owl	orcinol formation|orcinol biosynthesis|orcinol anabolism|orcinol synthesis													biological_process											owl:Class	
GO:0018312	biolink:NamedThing	peptidyl-serine ADP-ribosylation	The transfer, from NAD, of ADP-ribose to peptidyl-serine to form peptidyl-O-(ADP-ribosyl)-L-serine.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0237									biological_process											owl:Class	
GO:1900748	biolink:NamedThing	positive regulation of vascular endothelial growth factor signaling pathway	Any process that activates or increases the frequency, rate or extent of vascular endothelial growth factor signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	up regulation of VEGF-activated signaling pathway|upregulation of vascular endothelial growth factor signaling pathway|up-regulation of vascular endothelial growth factor signaling pathway|up regulation of vascular endothelial growth factor signalling pathway|positive regulation of VEGF-activated signaling pathway|positive regulation of vascular endothelial growth factor signalling pathway|upregulation of VEGF signaling|up-regulation of VEGF-activated signaling pathway|up-regulation of vascular endothelial growth factor signalling pathway|up regulation of VEGF signaling|upregulation of VEGF-activated signaling pathway|up regulation of vascular endothelial growth factor signaling pathway|activation of VEGF-activated signaling pathway|up-regulation of VEGF signaling|positive regulation of VEGF signaling|upregulation of vascular endothelial growth factor signalling pathway|activation of vascular endothelial growth factor signaling pathway|activation of VEGF signaling|activation of vascular endothelial growth factor signalling pathway							pm	2012-05-29T08:28:36Z					biological_process											owl:Class	
GO:1903026	biolink:NamedThing	negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding	Any process that stops, prevents or reduces the frequency, rate or extent of RNA polymerase II regulatory region sequence-specific DNA binding.	tmpzr1t_l9r_go_relaxed.owl	downregulation of RNA polymerase II regulatory region sequence-specific DNA binding|inhibition of RNA polymerase II regulatory region sequence-specific DNA binding|down regulation of RNA polymerase II regulatory region sequence-specific DNA binding|down-regulation of RNA polymerase II regulatory region sequence-specific DNA binding							dph	2014-05-15T17:56:00Z					biological_process											owl:Class	
GO:0008535	biolink:NamedThing	respiratory chain complex IV assembly	The aggregation, arrangement and bonding together of a set of components to form respiratory chain complex IV (also known as cytochrome c oxidase), the terminal member of the respiratory chain of the mitochondrion and some aerobic bacteria. Cytochrome c oxidases are multi-subunit enzymes containing from 13 subunits in the mammalian mitochondrial form to 3-4 subunits in the bacterial forms.	tmpzr1t_l9r_go_relaxed.owl	cytochrome c oxidase biogenesis|cytochrome c oxidase complex assembly													biological_process											owl:Class	
GO:0052877	biolink:NamedThing	oxidoreductase activity, acting on the CH-NH2 group of donors, with a copper protein as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH2 group acts as a hydrogen or electron donor and a copper protein is the acceptor.	tmpzr1t_l9r_go_relaxed.owl					EC:1.4.9.-									molecular_function											owl:Class	
GO:0033827	biolink:NamedThing	high-mannose-oligosaccharide beta-1,4-N-acetylglucosaminyltransferase activity	Catalysis of the transfer of an N-acetyl-D-glucosamine residue from UDP-N-acetyl-D-glucosamine to the 4-position of a mannose linked alpha-1,6 to the core mannose of high-mannose oligosaccharides produced by Dictyostelium discoideum.	tmpzr1t_l9r_go_relaxed.owl	UDP-N-acetyl-D-glucosamine:high-mannose-oligosaccharide beta-1,4-N-acetylglucosaminyltransferase activity|UDP-GlcNAc:oligosaccharide beta-N-acetylglucosaminyltransferase activity|acetylglucosamine-oligosaccharide acetylglucosaminyltransferase activity|uridine diphosphoacetylglucosamine-oligosaccharide acetylglucosaminyltransferase activity				MetaCyc:2.4.1.197-RXN|EC:2.4.1.197									molecular_function											owl:Class	
GO:1900436	biolink:NamedThing	positive regulation of filamentous growth of a population of unicellular organisms in response to starvation	Any process that activates or increases the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to starvation.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of filamentous growth of a population of unicellular organisms in response to starvation|up regulation of filamentous growth of a population of unicellular organisms in response to starvation|upregulation of filamentous growth of a population of unicellular organisms in response to starvation|activation of filamentous growth of a population of unicellular organisms in response to starvation							di	2012-04-25T05:55:05Z					biological_process											owl:Class	
GO:0043488	biolink:NamedThing	regulation of mRNA stability	Any process that modulates the propensity of mRNA molecules to degradation. Includes processes that both stabilize and destabilize mRNAs.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0004398	biolink:NamedThing	histidine decarboxylase activity	Catalysis of the reaction: L-histidine = histamine + CO2.	tmpzr1t_l9r_go_relaxed.owl	L-histidine carboxy-lyase activity|L-histidine carboxy-lyase (histamine-forming)|L-histidine decarboxylase activity				MetaCyc:HISTIDINE-DECARBOXYLASE-RXN|RHEA:20840|EC:4.1.1.22|Reactome:R-HSA-977301									molecular_function											owl:Class	
GO:0047388	biolink:NamedThing	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase	Catalysis of the reaction: adenylyl-[L-glutamate:ammonia ligase (ADP-forming)] + H2O = AMP + [L-glutamate:ammonia ligase (ADP-forming)].	tmpzr1t_l9r_go_relaxed.owl	adenylyl-glutamate-ammonia ligase hydrolase activity|adenylyl(glutamine synthetase) hydrolase activity|adenylyl-[glutamate-ammonia ligase] hydrolase activity|adenylyl-L-glutamate:ammonia ligase (ADP-forming) adenylylhydrolase activity|adenylyl-glutamine-synthetasehydrolase activity				KEGG_REACTION:R03474|EC:2.7.7.89|RHEA:43716|MetaCyc:3.1.4.15-RXN	Formerly EC:3.1.4.15.								molecular_function											owl:Class	
GO:0052808	biolink:NamedThing	reduced coenzyme F420:NADP+ oxidoreductase activity	Catalysis of the reaction: NADP+ + 1,5-dihydrocoenzyme F420 = NADPH + H+ + coenzyme F420. 1,5-dihydrocoenzyme F420 is also known as reduced coenzyme F420.	tmpzr1t_l9r_go_relaxed.owl	F420H2:NADP+ oxidoreductase activity|coenzyme F420-dependent NADP reductase activity|coenzyme F420-dependent NADP oxidoreductase activity|F420H2:NADP oxidoreductase activity|NADP+:F420 oxidoreductase activity				EC:1.5.1.40			ai	2011-09-22T04:08:13Z					molecular_function											owl:Class	
GO:1904667	biolink:NamedThing	negative regulation of ubiquitin protein ligase activity	Any process that stops, prevents or reduces the frequency, rate or extent of ubiquitin protein ligase activity.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of ubiquitin ligase activity|negative regulation of APC-fizzy related complex activity|downregulation of ubiquitin protein ligase activity|down-regulation of protein ubiquitination activity|downregulation of ubiquitin ligase activity|downregulation of E3|negative regulation of anaphase-promoting complex activity during mitotic cell cycle|inhibition of E3|down-regulation of ubiquitin ligase activity|negative regulation of E3|downregulation of protein ubiquitination activity|negative regulation of cyclosome activity during mitotic cell cycle|negative regulation of APC activity during mitotic cell cycle|down regulation of protein ubiquitination activity|down regulation of ubiquitin ligase activity|negative regulation of mitotic anaphase-promoting complex activity|negative regulation of APC-Cdc20 complex activity|down regulation of ubiquitin protein ligase activity|down-regulation of ubiquitin protein ligase activity|negative regulation of protein ubiquitination activity|negative regulation of APC/C activity during mitotic cell cycle|down-regulation of E3|down regulation of E3|inhibition of ubiquitin protein ligase activity|inhibition of ubiquitin ligase activity|inhibition of protein ubiquitination activity							dph	2015-09-08T15:27:05Z			GO:0060564|GO:1904190		biological_process											owl:Class	
GO:0046626	biolink:NamedThing	regulation of insulin receptor signaling pathway	Any process that modulates the frequency, rate or extent of insulin receptor signaling.	tmpzr1t_l9r_go_relaxed.owl	regulation of insulin receptor signalling pathway													biological_process											owl:Class	
GO:0032094	biolink:NamedThing	response to food	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a food stimulus; food is anything which, when taken into the body, serves to nourish or build up the tissues or to supply body heat.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0048320	biolink:NamedThing	axial mesoderm formation	The process that gives rise to the axial mesoderm. This process pertains to the initial formation of the structure from unspecified parts.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1905468	biolink:NamedThing	regulation of clathrin-coated pit assembly	Any process that modulates the frequency, rate or extent of clathrin-coated pit assembly.	tmpzr1t_l9r_go_relaxed.owl	regulation of clathrin-coated pit formation|regulation of coated pit assembly|regulation of coated pit formation							bf	2016-09-20T10:04:37Z					biological_process											owl:Class	
GO:1900371	biolink:NamedThing	regulation of purine nucleotide biosynthetic process	Any process that modulates the frequency, rate or extent of purine nucleotide biosynthetic processes.	tmpzr1t_l9r_go_relaxed.owl	regulation of purine nucleotide formation|regulation of purine nucleotide synthesis|regulation of purine nucleotide biosynthesis|regulation of purine nucleotide anabolism							krc	2012-04-17T12:32:07Z					biological_process											owl:Class	
GO:0072393	biolink:NamedThing	microtubule anchoring at microtubule organizing center	Any process in which a microtubule is maintained in a specific location in a cell by attachment to a microtubule organizing center.	tmpzr1t_l9r_go_relaxed.owl	microtubule anchoring at microtubule organising centre|microtubule anchoring at MTOC							mah	2010-12-07T11:54:35Z					biological_process											owl:Class	
GO:0120119	biolink:NamedThing	flagellum attachment zone	A network of cytoskeletal and membranous connections responsible for the lateral attachment of the cilium to the cell body in some trypanosomatid species.	tmpzr1t_l9r_go_relaxed.owl	FAZ					Note that we deem cilium and microtubule-based flagellum to be equivalent; the primary term name reflects frequency of use.		krc	2017-12-11T22:46:43Z					cellular_component											owl:Class	
GO:0038033	biolink:NamedThing	positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway	A series of molecular signals initiated by the binding of a vascular endothelial growth factor (VEGF) to a VEGFR on the surface of a cell, which activates or increases the frequency, rate or extent of endothelial cell chemotaxis.	tmpzr1t_l9r_go_relaxed.owl	VEGF-VEGFR-induced endothelial cell chemotaxis|positive regulation of endothelial cell chemotaxis by VEGF/VEGFR signaling pathway|vascular endothelial growth factor receptor signaling pathway involved in endothelial cell chemotaxis|VEGF-mediated chemotactic endothelial cell migration|positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signalling pathway							bf	2011-09-19T02:36:37Z					biological_process											owl:Class	
GO:0020038	biolink:NamedThing	subpellicular network	A mechanically stable cytoskeletal structure associated with the cytoplasmic face of the pellicle and surrounding the microtubule-based cytoskeleton.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0019306	biolink:NamedThing	GDP-D-rhamnose biosynthetic process	The chemical reactions and pathways resulting in the formation of GDP-D-rhamnose, a substance composed of rhamnose in glycosidic linkage with guanosine diphosphate.	tmpzr1t_l9r_go_relaxed.owl	GDP-D-rhamnose formation|GDP-D-rhamnose biosynthesis|GDP-D-rhamnose synthesis|GDP-D-rhamnose anabolism				MetaCyc:GDPRHAMSYN-PWY									biological_process											owl:Class	
GO:0046382	biolink:NamedThing	GDP-D-rhamnose metabolic process	The chemical reactions and pathways involving GDP-D-rhamnose, a substance composed of rhamnose in glycosidic linkage with guanosine diphosphate.	tmpzr1t_l9r_go_relaxed.owl	GDP-D-rhamnose metabolism													biological_process											owl:Class	
GO:0102755	biolink:NamedThing	gibberellin-15(closed lactone form),2-oxoglutarate:oxygen oxidoreductase (3beta-hydroxylating) activity	Catalysis of the reaction: gibberellin A15 (closed lactone form) + O2 + 2-oxoglutarate = gibberellin A37 (closed lactone form) + succinate + carbon dioxide.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-7680									molecular_function											owl:Class	
GO:0033144	biolink:NamedThing	negative regulation of intracellular steroid hormone receptor signaling pathway	Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of any intracellular steroid hormone receptor signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of steroid hormone receptor signaling pathway|negative regulation of steroid hormone receptor signalling pathway													biological_process											owl:Class	
GO:2000400	biolink:NamedThing	positive regulation of thymocyte aggregation	Any process that activates or increases the frequency, rate or extent of thymocyte aggregation.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of thymic lymphocyte aggregation|positive regulation of T cell precursor aggregation|positive regulation of immature T-lymphocyte aggregation|positive regulation of immature T-cell aggregation|positive regulation of immature T cell aggregation							mah	2011-02-22T02:50:01Z					biological_process											owl:Class	
GO:2000398	biolink:NamedThing	regulation of thymocyte aggregation	Any process that modulates the frequency, rate or extent of thymocyte aggregation.	tmpzr1t_l9r_go_relaxed.owl	regulation of thymic lymphocyte aggregation|regulation of immature T-cell aggregation|regulation of immature T-lymphocyte aggregation|regulation of T cell precursor aggregation|regulation of immature T cell aggregation							mah	2011-02-22T02:49:19Z					biological_process											owl:Class	
GO:0102534	biolink:NamedThing	apigenin-7,4'-dimethyl ether 6-hydroxylase activity	Catalysis of the reaction: apigenin-7,4'-dimethyl ether + O2 + NADPH + H+ <=> ladanein + H2O + NADP.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-14751									molecular_function											owl:Class	
GO:0090255	biolink:NamedThing	cell proliferation involved in imaginal disc-derived wing morphogenesis	The multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to imaginal disc-derived wing morphogenesis.	tmpzr1t_l9r_go_relaxed.owl								tb	2010-01-22T11:40:46Z					biological_process											owl:Class	
GO:0140585	biolink:NamedThing	promoter-enhancer loop anchoring activity	Bridging together two cis-regulatory elements, colloquially referred to as promoters and/or enhancers, holding two loop anchors together to maintain a chromatin loop.	tmpzr1t_l9r_go_relaxed.owl	enhancer-promoter loop anchoring activity	https://github.com/geneontology/go-ontology/issues/20204				Note that GO does not separately defines enhancers, since this concept is very close to that of cis-regulatory elements. However the literature refers to 'promoter-enhancer loops' to describe loops that bring together cis-regulatory elements. Note also that while SO defines 'promoter' as the core promoter, here it is used to mean a cis-regulatory element.		pg	2021-02-04T14:50:04Z					molecular_function											owl:Class	
GO:0030158	biolink:NamedThing	protein xylosyltransferase activity	Catalysis of the transfer of a beta-D-xylosyl residue from UDP-D-xylose to the serine hydroxyl group of an acceptor protein substrate.	tmpzr1t_l9r_go_relaxed.owl	UDP-D-xylose:core protein xylosyltransferase activity|UDP-D-xylose:protein beta-D-xylosyltransferase activity|UDP-D-xylose:proteoglycan core protein beta-D-xylosyltransferase activity|uridine diphosphoxylose-protein xylosyltransferase activity|UDP-D-xylose:core protein beta-D-xylosyltransferase activity|UDP-xylose-core protein beta-D-xylosyltransferase activity|peptide O-xylosyltransferase activity|uridine diphosphoxylose-core protein beta-xylosyltransferase activity				MetaCyc:2.4.2.26-RXN|Reactome:R-HSA-1878002|RHEA:50192|EC:2.4.2.26									molecular_function											owl:Class	
GO:1900187	biolink:NamedThing	regulation of cell adhesion involved in single-species biofilm formation	Any process that modulates the frequency, rate or extent of cell adhesion involved in single-species biofilm formation.	tmpzr1t_l9r_go_relaxed.owl	regulation of cell adhesion during single-species biofilm formation							di	2012-03-19T12:38:45Z					biological_process											owl:Class	
GO:0014809	biolink:NamedThing	regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion	Any process that modulates the frequency, rate or extent of skeletal muscle contraction via the regulation of the release of sequestered calcium ion by sarcoplasmic reticulum into cytosol. The sarcoplasmic reticulum is the endoplasmic reticulum of striated muscle, specialised for the sequestration of calcium ions that are released upon receipt of a signal relayed by the T tubules from the neuromuscular junction.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0090362	biolink:NamedThing	positive regulation of platelet-derived growth factor production	Any process that increases the rate, frequency, or extent of the appearance of any platelet-derived growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	tmpzr1t_l9r_go_relaxed.owl								tb	2010-07-12T10:32:27Z					biological_process											owl:Class	
GO:1990854	biolink:NamedThing	vacuole-ER tethering	The attachment of a lytic vacuole to the endoplasmic reticulum, which may facilitate exchange of metabolites between the organelles.	tmpzr1t_l9r_go_relaxed.owl	vacuole-endoplasmic reticulum attachment|vacuole-endoplasmic reticulum tethering|vacuole-ER attachment							mcc	2015-09-15T18:50:04Z					biological_process											owl:Class	
GO:1905893	biolink:NamedThing	positive regulation of cellular response to thapsigargin	Any process that activates or increases the frequency, rate or extent of cellular response to thapsigargin.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of cellular response to thapsigargin|up regulation of cellular response to thapsigargin|upregulation of cellular response to thapsigargin|activation of cellular response to thapsigargin							bc	2017-02-01T11:36:24Z					biological_process											owl:Class	
GO:1905891	biolink:NamedThing	regulation of cellular response to thapsigargin	Any process that modulates the frequency, rate or extent of cellular response to thapsigargin.	tmpzr1t_l9r_go_relaxed.owl								bc	2017-02-01T11:36:07Z					biological_process											owl:Class	
GO:0008967	biolink:NamedThing	phosphoglycolate phosphatase activity	Catalysis of the reaction: 2-phosphoglycolate + H(2)O = glycolate + phosphate.	tmpzr1t_l9r_go_relaxed.owl	2-phosphoglycolate phosphohydrolase activity|P-glycolate phosphatase activity|phosphoglycolate hydrolase activity|phosphoglycollate phosphatase activity|2-phosphoglycolate phosphatase activity				KEGG_REACTION:R01334|EC:3.1.3.18|RHEA:14369|MetaCyc:GPH-RXN									molecular_function											owl:Class	
GO:1902560	biolink:NamedThing	GMP reductase complex	An oxidoreductase complex which is capable of GMP reductase activity. It catalyses the irreversible reaction: GMP + 2 H(+) + NADPH => IMP + NADP(+) + NH(4)(+).	tmpzr1t_l9r_go_relaxed.owl	guanosine monophosphate reductase|GMPR1 complex|GMP reductase|GMPR2 complex					An example of this is GMPR2 in human (UniProt Symbol Q9P2T1) in PMID:12009299 (inferred from direct assay).		bhm	2013-12-10T11:54:30Z					cellular_component											owl:Class	
GO:0051443	biolink:NamedThing	positive regulation of ubiquitin-protein transferase activity	Any process that activates, maintains or increases the rate of ubiquitin transferase activity.	tmpzr1t_l9r_go_relaxed.owl	SCF complex activator|anaphase promoting complex activator|up-regulation of ubiquitin transferase activity|upregulation of ubiquitin transferase activity|anaphase-promoting complex activator|ubiquitin transferase activator|APC activation|APC activator|positive regulation of ubiquitin transferase activity|activation of ubiquitin transferase activity|stimulation of ubiquitin transferase activity|up regulation of ubiquitin ligase activity													biological_process											owl:Class	
GO:0008789	biolink:NamedThing	altronate dehydratase activity	Catalysis of the reaction: D-altronate = 2-dehydro-3-deoxy-D-gluconate + H(2)O.	tmpzr1t_l9r_go_relaxed.owl	D-altronate hydro-lyase (2-dehydro-3-deoxy-D-galactonate-forming)|D-altronate hydro-lyase activity				EC:4.2.1.7|RHEA:15957|KEGG_REACTION:R01540|MetaCyc:ALTRODEHYDRAT-RXN									molecular_function											owl:Class	
GO:0051177	biolink:NamedThing	meiotic sister chromatid cohesion	The cell cycle process in which sister chromatids of a replicated chromosome are joined along the entire length of the chromosome during meiosis.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1904356	biolink:NamedThing	regulation of telomere maintenance via telomere lengthening	Any process that modulates the frequency, rate or extent of telomere maintenance via telomere lengthening.	tmpzr1t_l9r_go_relaxed.owl								nc	2015-06-12T16:53:16Z					biological_process											owl:Class	
GO:0072685	biolink:NamedThing	Mre11 complex assembly	The aggregation, arrangement and bonding together of a set of components to form an Mre11 complex, a trimeric protein complex that possesses endonuclease activity and is involved in meiotic recombination, DNA repair and checkpoint signaling.	tmpzr1t_l9r_go_relaxed.owl	Rad50 complex assembly|MRN complex assembly|MRX complex assembly|Rad50-Rad32-Nbs1 complex assembly|RMX complex assembly|RAD50-MRE11-NBN complex assembly							mah	2011-05-12T02:52:06Z					biological_process											owl:Class	
GO:1990547	biolink:NamedThing	mitochondrial phosphate ion transmembrane transport	The process in which a phosphate ion is transported across a mitochondrial membrane, into or out of the mitochondrion.	tmpzr1t_l9r_go_relaxed.owl								vw	2014-11-19T11:50:19Z					biological_process											owl:Class	
GO:0008684	biolink:NamedThing	2-oxopent-4-enoate hydratase activity	Catalysis of the reaction: 4-hydroxy-2-oxopentanoate = 2-oxopent-4-enoate + H2O.	tmpzr1t_l9r_go_relaxed.owl	OEH activity|2-keto-4-pentenoate hydratase activity|2-keto-4-pentenoate (vinylpyruvate)hydratase activity|4-hydroxy-2-oxopentanoate hydro-lyase activity|4-hydroxy-2-oxopentanoate hydro-lyase (2-oxopent-4-enoate-forming)				UM-BBD_enzymeID:e0078|EC:4.2.1.80|MetaCyc:2-OXOPENT-4-ENOATE-HYDRATASE-RXN|RHEA:22580							GO:0018821		molecular_function											owl:Class	
GO:1904366	biolink:NamedThing	negative regulation of chemokinesis	Any process that stops, prevents or reduces the frequency, rate or extent of chemokinesis.	tmpzr1t_l9r_go_relaxed.owl	down regulation of chemokinesis|downregulation of chemokinesis|inhibition of chemokinesis|down-regulation of chemokinesis							sl	2015-06-15T22:44:12Z					biological_process											owl:Class	
GO:0047417	biolink:NamedThing	N-carbamoyl-D-amino acid hydrolase activity	Catalysis of the reaction: H2O + N-carbamoyl-D-amino acid = CO2 + NH3 + D-amino acid.	tmpzr1t_l9r_go_relaxed.owl	N-carbamoyl-D-amino acid amidohydrolase activity				RHEA:11000|MetaCyc:3.5.1.77-RXN|EC:3.5.1.77									molecular_function											owl:Class	
GO:0015808	biolink:NamedThing	L-alanine transport	The directed movement of L-alanine, the L-enantiomer of 2-aminopropanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0102922	biolink:NamedThing	phenylpropanoyltransferase activity	Catalysis of the reaction: baccatin III + (3R)-3-amino-3-phenylpropanoyl-CoA = N-debenzoyl-(3'-RS)-2'-deoxytaxol + coenzyme A.	tmpzr1t_l9r_go_relaxed.owl					RHEA:42488|MetaCyc:RXN-8857									molecular_function											owl:Class	
GO:0021896	biolink:NamedThing	forebrain astrocyte differentiation	The process in which a relatively unspecialized cell acquires the specialized features of an astrocyte residing in the forebrain. An astrocyte is the most abundant type of glial cell. Astrocytes provide support for neurons and regulate the environment in which they function.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0048708	biolink:NamedThing	astrocyte differentiation	The process in which a relatively unspecialized cell acquires the specialized features of an astrocyte. An astrocyte is the most abundant type of glial cell. Astrocytes provide support for neurons and regulate the environment in which they function.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0004125	biolink:NamedThing	L-seryl-tRNASec selenium transferase activity	Catalysis of the reaction: L-seryl-tRNA(Sec) + selenophosphate = L-selenocysteinyl-tRNA(Sec) + H2O + phosphate.	tmpzr1t_l9r_go_relaxed.owl	L-selenocysteinyl-tRNASel synthase activity|L-selenocysteinyl-tRNA(Sel) synthase activity|cysteinyl-tRNA(Sec)-selenium transferase activity|cysteinyl-tRNA(Sel)-selenium transferase activity|selenocysteine synthase activity|cysteinyl-tRNASel-selenium transferase activity|L-seryl-tRNA(Ser) selenium transferase activity|cysteinyl-tRNASec-selenium transferase activity|L-selenocysteinyl-tRNASec synthase activity|selenophosphate:L-seryl-tRNASec selenium transferase activity|cysteinyl-tRNA(Ser) selenium transferase activity|L-selenocysteinyl-tRNA(Sec) synthase activity|selenocysteinyl-tRNA(Ser) synthase activity				EC:2.9.1.1|RHEA:22728|MetaCyc:2.9.1.1-RXN									molecular_function											owl:Class	
GO:0047393	biolink:NamedThing	glycerol-1,2-cyclic-phosphate 2-phosphodiesterase activity	Catalysis of the reaction: glycerol 1,2-cyclic phosphate + H(2)O = glycerol 1-phosphate + H(+).	tmpzr1t_l9r_go_relaxed.owl	rac-glycerol 1:2-cyclic phosphate 2-phosphodiesterase activity|rac-glycerol-1,2-cyclic-phosphate 2-glycerophosphohydrolase activity				RHEA:16493|EC:3.1.4.42|KEGG_REACTION:R02648|MetaCyc:3.1.4.42-RXN									molecular_function											owl:Class	
GO:0103064	biolink:NamedThing	inositol phosphorylceramide mannosyltransferase activity	Catalysis of the reaction: a 1D-myo-inositol-1-phospho-N-[(R)-2-hydroxy-very-long-chain fatty acyl]-(R)-4-hydroxysphingoid base + GDP-alpha-D-mannose = an alpha-D-mannosyl-(1,6)-1D-myo-inositol-1-phospho-N-[(R)-2-hydroxy-very-long-chain fatty acyl]-(R)-4-hydroxysphingoid base + GDP + H+.	tmpzr1t_l9r_go_relaxed.owl					EC:2.4.1.370|https://github.com/geneontology/go-ontology/issues/21803|RHEA:64596|MetaCyc:RXN3O-663									molecular_function											owl:Class	
GO:2001115	biolink:NamedThing	methanopterin-containing compound metabolic process	The chemical reactions and pathways involving a methanopterin.	tmpzr1t_l9r_go_relaxed.owl	methanopterin metabolism							jl	2011-10-11T11:54:56Z					biological_process											owl:Class	
GO:0000024	biolink:NamedThing	maltose biosynthetic process	The chemical reactions and pathways resulting in the formation of the disaccharide maltose (4-O-alpha-D-glucopyranosyl-D-glucopyranose).	tmpzr1t_l9r_go_relaxed.owl	malt sugar biosynthesis|maltose biosynthesis|maltose anabolism|maltose formation|malt sugar biosynthetic process|maltose synthesis													biological_process											owl:Class	
GO:0000023	biolink:NamedThing	maltose metabolic process	The chemical reactions and pathways involving the disaccharide maltose (4-O-alpha-D-glucopyranosyl-D-glucopyranose), an intermediate in the catabolism of glycogen and starch.	tmpzr1t_l9r_go_relaxed.owl	malt sugar metabolism|maltose metabolism|malt sugar metabolic process													biological_process											owl:Class	
GO:0048321	biolink:NamedThing	axial mesodermal cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of an axial mesoderm cell.	tmpzr1t_l9r_go_relaxed.owl	axial mesoderm cell differentiation													biological_process											owl:Class	
GO:0071752	biolink:NamedThing	secretory dimeric IgA immunoglobulin complex	A dimeric form of secretory IgA immunoglobulin complex.	tmpzr1t_l9r_go_relaxed.owl	secretory dimeric IgA antibody|secretory dimeric IgA1 antibody					Note that an IgA immunoglobulin complex has the function of antigen binding if a suitable antigen is available. Dimeric IgA is by far the most common form of polymeric IgA. In human only the IgA1 isotype is capable of a dimeric form.		mah	2010-03-24T01:44:53Z					cellular_component											owl:Class	
GO:0071751	biolink:NamedThing	secretory IgA immunoglobulin complex	A polymeric IgA immunoglobulin complex that is complexed with one chain of secretory component (SC). Polymeric IgA is present in mucosal areas, having been transported via a transcytosis mechanism in mucosal epithelial cells relying on the polymeric Ig receptor, a portion of which then remains bound to the polymeric IgA as secretory component.	tmpzr1t_l9r_go_relaxed.owl	sIgA antibody|secretory IgA antibody|sIgA1 antibody					Note that an IgA immunoglobulin complex has the function of antigen binding if a suitable antigen is available. In human only the IgA1 isotype in the polymeric form is capable of becoming secretory IgA.		mah	2010-03-24T01:44:53Z					cellular_component											owl:Class	
GO:0006691	biolink:NamedThing	leukotriene metabolic process	The chemical reactions and pathways involving leukotriene, a pharmacologically active substance derived from a polyunsaturated fatty acid, such as arachidonic acid.	tmpzr1t_l9r_go_relaxed.owl	leukotriene metabolism													biological_process											owl:Class	
GO:0032464	biolink:NamedThing	positive regulation of protein homooligomerization	Any process that activates or increases the frequency, rate or extent of protein homooligomerization.	tmpzr1t_l9r_go_relaxed.owl	upregulation of protein homooligomerization|up-regulation of protein homooligomerization|activation of protein homooligomerization|stimulation of protein homooligomerization|induction of protein homooligomerization|up regulation of protein homooligomerization													biological_process											owl:Class	
GO:0030975	biolink:NamedThing	thiamine binding	Binding to thiamine (vitamin B1), a water soluble vitamin present in fresh vegetables and meats, especially liver.	tmpzr1t_l9r_go_relaxed.owl	vitamin B1 binding|thiamin binding													molecular_function											owl:Class	
GO:0003349	biolink:NamedThing	epicardium-derived cardiac endothelial cell differentiation	The process in which an epicardial cell acquires the specialized structural and/or functional features of a cardiac endothelial cell.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-12-01T11:17:49Z					biological_process											owl:Class	
GO:0034525	biolink:NamedThing	1-naphthaldehyde dehydrogenase activity	Catalysis of the reaction: 1-naphthaldehyde + NAD+ + H2O = 1-naphthoic acid + NADH + H+.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0787									molecular_function											owl:Class	
GO:0033443	biolink:NamedThing	AAA codon-amino acid adaptor activity	A triplet codon-amino acid adaptor activity that recognizes an AAA codon.	tmpzr1t_l9r_go_relaxed.owl	lysine tRNA					Note that in the standard genetic code, AAA codes for lysine.								molecular_function											owl:Class	
GO:0033054	biolink:NamedThing	D-glutamate metabolic process	The chemical reactions and pathways involving D-glutamate, the D-enantiomer of the amino acid glutamate, i.e. (2R)-2-aminopentanedioic acid.	tmpzr1t_l9r_go_relaxed.owl	D-glutamate metabolism													biological_process											owl:Class	
GO:0031706	biolink:NamedThing	subtype 3 bombesin receptor binding	Binding to a subtype 3 bombesin receptor.	tmpzr1t_l9r_go_relaxed.owl	subtype 3 bombesin receptor ligand													molecular_function											owl:Class	
GO:0003232	biolink:NamedThing	bulbus arteriosus development	The process whose specific outcome is the progression of the bulbus arteriosus over time, from its formation to the mature structure. The bulbus arteriosus is an elastic heart chamber.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-10-13T11:05:36Z					biological_process											owl:Class	
GO:0021851	biolink:NamedThing	neuroblast division in dorsal lateral ganglionic eminence	The division of neuroblasts in the dorsal region of the lateral ganglionic eminence. These cells give rise to embryonic interneuron precursors that will migrate tangentially to the olfactory bulb.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0001857	biolink:NamedThing	complement component C1q receptor activity	Combining with the C1q complex, a component of the classical complement cascade, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0086093	biolink:NamedThing	G protein-coupled acetylcholine receptor signaling pathway involved in heart process	A G protein-coupled acetylcholine receptor signaling pathway, which contributes to a circulatory system process carried out by the heart.	tmpzr1t_l9r_go_relaxed.owl	M2 receptor signaling pathway involved in heart process|muscarinic receptor signaling pathway involved in heart process|G-protein coupled acetylcholine receptor signaling pathway involved in heart process|G-protein coupled acetylcholine receptor signalling pathway involved in heart process							bf						biological_process											owl:Class	
GO:0046612	biolink:NamedThing	lysosomal proton-transporting V-type ATPase, V1 domain	The V1 domain of a proton-transporting V-type ATPase found in the lysosomal membrane.	tmpzr1t_l9r_go_relaxed.owl	lysosomal hydrogen ion-transporting ATPase V1 domain													cellular_component											owl:Class	
GO:0033180	biolink:NamedThing	proton-transporting V-type ATPase, V1 domain	A protein complex that forms part of a proton-transporting V-type ATPase and catalyzes ATP hydrolysis. The V1 complex consists of: (1) a globular headpiece with three alternating copies of subunits A and B that form a ring, (2) a central rotational stalk composed of single copies of subunits D and F, and (3) a peripheral stalk made of subunits C, E, G and H. Subunits A and B mediate the hydrolysis of ATP at three reaction sites associated with subunit A.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:1900832	biolink:NamedThing	D-leucine catabolic process	The chemical reactions and pathways resulting in the breakdown of D-leucine.	tmpzr1t_l9r_go_relaxed.owl	D-leucine breakdown|D-leucine degradation|D-leucine catabolism							se	2012-06-06T09:37:40Z					biological_process											owl:Class	
GO:0000756	biolink:NamedThing	response to pheromone regulating conjugation with mutual genetic exchange	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pheromone stimulus regulating the process of conjugation without cellular fusion.	tmpzr1t_l9r_go_relaxed.owl	response to pheromone triggering conjugation without cellular fusion													biological_process											owl:Class	
GO:0071224	biolink:NamedThing	cellular response to peptidoglycan	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptidoglycan stimulus. Peptidoglycan is a bacterial cell wall macromolecule.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-12-03T01:36:38Z					biological_process											owl:Class	
GO:0019208	biolink:NamedThing	phosphatase regulator activity	Binds to and modulates the activity of a phosphatase, an enzyme which catalyzes of the removal of a phosphate group from a substrate molecule.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0061095	biolink:NamedThing	positive regulation of turning behavior involved in mating	Any process that increases the rate, frequency or extent of turning behavior involved in mating. Turning behavior is the sharp ventral turn performed by the male as he approaches either the hermaphrodite head or tail, whilst trying to locate his partner's vulva. Turning occurs via a sharp ventral coil of the male's tail.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-04-26T02:12:24Z					biological_process											owl:Class	
GO:0004900	biolink:NamedThing	erythropoietin receptor activity	Combining with erythropoietin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0090256	biolink:NamedThing	regulation of cell proliferation involved in imaginal disc-derived wing morphogenesis	Any process that modulates the frequency, rate, or extent of the multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to imaginal disc-derived wing morphogenesis.	tmpzr1t_l9r_go_relaxed.owl								tb	2010-01-22T11:40:46Z					biological_process											owl:Class	
GO:0010755	biolink:NamedThing	regulation of plasminogen activation	Any process that modulates the rate, frequency or extent of plasminogen activation. Plasminogen activation is the process in which plasminogen is processed to plasmin.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0048491	biolink:NamedThing	retrograde synaptic vesicle transport	The directed movement of synaptic vesicle along axonal microtubules from the presynapse to the cell body.	tmpzr1t_l9r_go_relaxed.owl	retrograde axonal transport of synaptic vesicle													biological_process											owl:Class	
GO:0035696	biolink:NamedThing	monocyte extravasation	The migration of a monocyte from the blood vessels into the surrounding tissue.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-02-28T03:05:52Z					biological_process											owl:Class	
GO:0047850	biolink:NamedThing	diaminopimelate dehydrogenase activity	Catalysis of the reaction: meso-2,6-diaminopimelate + H(2)O + NADP(+) = L-2-amino-6-oxopimelate + H(+) + NADPH + NH(4)(+).	tmpzr1t_l9r_go_relaxed.owl	meso-2,6-diaminoheptanedioate:NADP+ oxidoreductase (deaminating)|meso-alpha,epsilon-diaminopimelate dehydrogenase activity|meso-diaminopimelate D-dehydrogenase activity|meso-diaminopimelate dehydrogenase activity				EC:1.4.1.16|KEGG_REACTION:R02755|RHEA:13561|MetaCyc:DIAMINOPIMELATE-DEHYDROGENASE-RXN									molecular_function											owl:Class	
GO:0000064	biolink:NamedThing	L-ornithine transmembrane transporter activity	Enables the transfer of L-ornithine from one side of a membrane to the other. L-ornithine is 2,5-diaminopentanoic acid.	tmpzr1t_l9r_go_relaxed.owl	histidine/arginine/lysine/ornithine porter activity|L-ornithine transporter activity				Reactome:R-HSA-70634									molecular_function											owl:Class	
GO:0051569	biolink:NamedThing	regulation of histone H3-K4 methylation	Any process that modulates the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 4 of histone H3.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0030810	biolink:NamedThing	positive regulation of nucleotide biosynthetic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nucleotides.	tmpzr1t_l9r_go_relaxed.owl	activation of nucleotide biosynthetic process|up regulation of nucleotide biosynthetic process|up-regulation of nucleotide biosynthetic process|positive regulation of nucleotide synthesis|positive regulation of nucleotide formation|stimulation of nucleotide biosynthetic process|upregulation of nucleotide biosynthetic process|positive regulation of nucleotide biosynthesis|positive regulation of nucleotide anabolism													biological_process											owl:Class	
GO:0050320	biolink:NamedThing	tartrate epimerase activity	Catalysis of the reaction: L-tartrate = (2R,3S)-tartrate.	tmpzr1t_l9r_go_relaxed.owl	tartaric racemase activity				MetaCyc:TARTRATE-EPIMERASE-RXN|RHEA:22212|KEGG_REACTION:R02546|EC:5.1.2.5									molecular_function											owl:Class	
GO:0010414	biolink:NamedThing	glucuronoarabinoxylan metabolic process	The chemical reactions and pathways involving xylan, a polymer containing a beta-(1->4)-linked D-xylose backbone decorated with glucuronic acid and arabinose side units.	tmpzr1t_l9r_go_relaxed.owl	glucuronoarabinoxylan metabolism													biological_process											owl:Class	
GO:0010416	biolink:NamedThing	arabinoxylan-containing compound metabolic process	The chemical reactions and pathways involving an arabinoxylan, a polymer containing a beta-1,4-linked D-xylose backbone decorated with arabinose side units.	tmpzr1t_l9r_go_relaxed.owl	arabinoxylan metabolic process|arabinoxylan metabolism													biological_process											owl:Class	
GO:0002666	biolink:NamedThing	positive regulation of T cell tolerance induction	Any process that activates or increases the frequency, rate, or extent of T cell tolerance induction.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of T-lymphocyte tolerance induction|up regulation of T cell tolerance induction|positive regulation of T-cell tolerance induction|upregulation of T cell tolerance induction|up-regulation of T cell tolerance induction|positive regulation of T lymphocyte tolerance induction|stimulation of T cell tolerance induction|activation of T cell tolerance induction													biological_process											owl:Class	
GO:0006152	biolink:NamedThing	purine nucleoside catabolic process	The chemical reactions and pathways resulting in the breakdown of purine nucleoside, one of a family of organic molecules consisting of a purine base covalently bonded to a sugar ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside).	tmpzr1t_l9r_go_relaxed.owl	purine nucleoside breakdown|purine nucleoside catabolism|purine nucleoside degradation													biological_process											owl:Class	
GO:0042278	biolink:NamedThing	purine nucleoside metabolic process	The chemical reactions and pathways involving one of a family of organic molecules consisting of a purine base covalently bonded to a sugar ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside).	tmpzr1t_l9r_go_relaxed.owl	purine nucleoside metabolism|purine metabolism|purine metabolic process													biological_process											owl:Class	
GO:1903789	biolink:NamedThing	regulation of amino acid transmembrane transport	Any process that modulates the frequency, rate or extent of amino acid transmembrane transport.	tmpzr1t_l9r_go_relaxed.owl	regulation of amino acid membrane transport							al	2015-01-08T17:42:18Z					biological_process											owl:Class	
GO:0015255	biolink:NamedThing	propanediol channel activity	Enables the facilitated diffusion of propanediol (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0032115	biolink:NamedThing	sorbose reductase activity	Catalysis of the reaction: D-glucitol + NADP(+) = L-sorbose + H(+) + NADPH. The reaction may occur, to a minor extent, in the reverse direction.	tmpzr1t_l9r_go_relaxed.owl	Sou1p|D-glucitol:NADP+ oxidoreductase activity				RHEA:14609|EC:1.1.1.289|MetaCyc:1.1.1.289-RXN|KEGG_REACTION:R07346									molecular_function											owl:Class	
GO:0034471	biolink:NamedThing	ncRNA 5'-end processing	Any process involved in forming the mature 5' end of a non-coding RNA molecule.	tmpzr1t_l9r_go_relaxed.owl	ncRNA 5' end processing													biological_process											owl:Class	
GO:2001133	biolink:NamedThing	methane biosynthetic process from methanethiol	The chemical reactions and pathways resulting in the formation of a methane from a methanethiol.	tmpzr1t_l9r_go_relaxed.owl								jl	2011-10-13T12:32:57Z					biological_process											owl:Class	
GO:0106141	biolink:NamedThing	flavin prenyltransferase activity	Catalysis of the reaction: dimethylallylphosphate + FMNH2 = prenylated FMNH2 + phosphate.	tmpzr1t_l9r_go_relaxed.owl					EC:2.5.1.129|RHEA:37743			hjd	2018-08-17T18:50:00Z					molecular_function											owl:Class	
GO:0016602	biolink:NamedThing	CCAAT-binding factor complex	A heteromeric transcription factor complex that binds to the CCAAT-box upstream of promoters; functions as both an activator and a repressor, depending on its interacting cofactors. Typically trimeric consisting of NFYA, NFYB and NFYC subunits. In Saccharomyces, it activates the transcription of genes in response to growth in a nonfermentable carbon source and consists of four known subunits: HAP2, HAP3, HAP4 and HAP5.	tmpzr1t_l9r_go_relaxed.owl	nuclear transcription factor Y complex|NF-Y transcription factor complex|CBF complex													cellular_component											owl:Class	
GO:0101023	biolink:NamedThing	vascular endothelial cell proliferation	The multiplication or reproduction of blood vessel endothelial cells, resulting in the expansion of a cell population.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:2001279	biolink:NamedThing	regulation of unsaturated fatty acid biosynthetic process	Any process that modulates the frequency, rate or extent of unsaturated fatty acid biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of fatty acid desaturation|regulation of unsaturated fatty acid biosynthesis|regulation of polyunsaturated fatty acid biosynthesis|regulation of unsaturated fatty acid formation|regulation of unsaturated fatty acid synthesis|regulation of unsaturated fatty acid anabolism							dgf	2011-12-14T07:48:26Z					biological_process											owl:Class	
GO:0004607	biolink:NamedThing	phosphatidylcholine-sterol O-acyltransferase activity	Catalysis of the reaction: phosphatidylcholine + a sterol = a sterol ester + 1-acylglycerophosphocholine.	tmpzr1t_l9r_go_relaxed.owl	lecithin--cholesterol acyltransferase activity|phosphatidylcholine:sterol O-acyltransferase activity|phospholipid--cholesterol acyltransferase activity|lecithin:cholesterol acyltransferase activity|LCAT activity|LCAT (lecithin-cholesterol acyltransferase)				RHEA:21204|MetaCyc:2.3.1.43-RXN|Reactome:R-HSA-264695|EC:2.3.1.43									molecular_function											owl:Class	
GO:0034120	biolink:NamedThing	positive regulation of erythrocyte aggregation	Any process that activates or increases the frequency, rate, or extent of erythrocyte aggregation.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of RBC aggregation|positive regulation of red blood cell aggregation													biological_process											owl:Class	
GO:0032099	biolink:NamedThing	negative regulation of appetite	Any process that reduces appetite.	tmpzr1t_l9r_go_relaxed.owl	inhibition of appetite|down-regulation of appetite|appetite suppression|downregulation of appetite|down regulation of appetite|negative regulation of hunger													biological_process											owl:Class	
GO:0032096	biolink:NamedThing	negative regulation of response to food	Any process that stops, prevents, or reduces the frequency, rate or extent of a response to a food stimulus.	tmpzr1t_l9r_go_relaxed.owl	downregulation of response to food|inhibition of response to food|down-regulation of response to food|down regulation of response to food													biological_process											owl:Class	
GO:1990243	biolink:NamedThing	atf1-pcr1 complex	A heterodimeric transcription factor complex composed of the bZIP proteins atf1 and pcr1. The heterodimer binds m26 sites (homologous to CRE).	tmpzr1t_l9r_go_relaxed.owl								al	2013-11-28T11:40:28Z					cellular_component											owl:Class	
GO:0019298	biolink:NamedThing	coenzyme B biosynthetic process	The chemical reactions and pathways resulting in the formation of coenzyme B (7-mercaptoheptanoylthreonine phosphate), a coenzyme involved in the utilization of methane by methanogenic prokaryotes.	tmpzr1t_l9r_go_relaxed.owl	coenzyme B synthesis|coenzyme B formation|coenzyme B anabolism|coenzyme B biosynthesis				MetaCyc:P241-PWY									biological_process											owl:Class	
GO:1901798	biolink:NamedThing	positive regulation of signal transduction by p53 class mediator	Any process that activates or increases the frequency, rate or extent of signal transduction by p53 class mediator.	tmpzr1t_l9r_go_relaxed.owl	up regulation of signal transduction by p53 class mediator|upregulation of signal transduction by p53 class mediator|activation of signal transduction by p53 class mediator|up-regulation of signal transduction by p53 class mediator							hjd	2013-01-18T21:51:48Z					biological_process											owl:Class	
GO:2000938	biolink:NamedThing	positive regulation of cellotriose catabolic process	Any process that activates or increases the frequency, rate or extent of cellotriose catabolic process.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of cellotriose catabolism							tt	2011-08-01T12:45:35Z					biological_process											owl:Class	
GO:0036051	biolink:NamedThing	protein localization to trailing edge	A process in which a protein is transported to, or maintained at, the trailing edge. The trailing edge is the area of a motile cell opposite to the direction of movement.	tmpzr1t_l9r_go_relaxed.owl	protein localisation to trailing edge							bf	2011-12-12T10:44:04Z					biological_process											owl:Class	
GO:0006167	biolink:NamedThing	AMP biosynthetic process	The chemical reactions and pathways resulting in the formation of AMP, adenosine monophosphate.	tmpzr1t_l9r_go_relaxed.owl	AMP anabolism|AMP synthesis|AMP biosynthesis|AMP formation													biological_process											owl:Class	
GO:0103111	biolink:NamedThing	D-glucosamine PTS permease activity	Catalysis of the reaction: a [PTS enzyme I]-Npi-phospho-L-histidine + D-glucosamine <=> D-glucosamine 6-phosphate + a [PTS enzyme I]-L-histidine.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:TRANS-RXN-167A|EC:2.7.1.69|RHEA:37359									molecular_function											owl:Class	
GO:0051249	biolink:NamedThing	regulation of lymphocyte activation	Any process that modulates the frequency, rate or extent of lymphocyte activation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1902901	biolink:NamedThing	positive regulation of transcription from RNA polymerase II promoter involved in stress response to cadmium ion	Any positive regulation of transcription from RNA polymerase II promoter that is involved in stress response to cadmium ion.	tmpzr1t_l9r_go_relaxed.owl	activation of transcription from RNA polymerase II promoter involved in response to cadmium ion stress|positive regulation of gene-specific transcription from RNA polymerase II promoter involved in stress response to cadmium ion|activation of global transcription from RNA polymerase II promoter involved in stress response to cadmium ion|positive regulation of gene-specific transcription from RNA polymerase II promoter involved in response to cadmium ion stress|up regulation of transcription from RNA polymerase II promoter involved in response to cadmium ion stress|stimulation of global transcription from RNA polymerase II promoter involved in stress response to cadmium ion|up regulation of transcription from RNA polymerase II promoter involved in stress response to cadmium ion|positive regulation of transcription from RNA polymerase II promoter involved in response to cadmium ion stress|upregulation of global transcription from RNA polymerase II promoter involved in response to cadmium ion stress|upregulation of transcription from RNA polymerase II promoter involved in response to cadmium ion stress|up regulation of transcription from RNA polymerase II promoter involved in response to cadmium toxicity|positive regulation of global transcription from Pol II promoter involved in response to cadmium ion stress|activation of transcription from RNA polymerase II promoter involved in stress response to cadmium ion|positive regulation of gene-specific transcription from RNA polymerase II promoter involved in response to cadmium toxicity|up-regulation of transcription from RNA polymerase II promoter involved in response to cadmium ion stress|upregulation of global transcription from RNA polymerase II promoter involved in response to cadmium toxicity|up regulation of global transcription from RNA polymerase II promoter involved in response to cadmium toxicity|stimulation of global transcription from RNA polymerase II promoter involved in response to cadmium ion stress|up regulation of global transcription from RNA polymerase II promoter involved in stress response to cadmium ion|positive regulation of global transcription from Pol II promoter involved in stress response to cadmium ion|upregulation of global transcription from RNA polymerase II promoter involved in stress response to cadmium ion|stimulation of global transcription from RNA polymerase II promoter involved in response to cadmium toxicity|positive regulation of global transcription from Pol II promoter involved in response to cadmium toxicity|up-regulation of global transcription from RNA polymerase II promoter involved in stress response to cadmium ion|stimulation of transcription from RNA polymerase II promoter involved in response to cadmium ion stress|up-regulation of transcription from RNA polymerase II promoter involved in stress response to cadmium ion|activation of global transcription from RNA polymerase II promoter involved in response to cadmium toxicity|up regulation of global transcription from RNA polymerase II promoter involved in response to cadmium ion stress|positive regulation of transcription from Pol II promoter involved in response to cadmium ion stress|positive regulation of transcription from RNA polymerase II promoter involved in response to cadmium toxicity|upregulation of transcription from RNA polymerase II promoter involved in response to cadmium toxicity|positive regulation of transcription from Pol II promoter involved in response to cadmium toxicity|activation of transcription from RNA polymerase II promoter involved in response to cadmium toxicity|up-regulation of transcription from RNA polymerase II promoter involved in response to cadmium toxicity|stimulation of transcription from RNA polymerase II promoter involved in response to cadmium toxicity|positive regulation of transcription from Pol II promoter involved in stress response to cadmium ion|up-regulation of global transcription from RNA polymerase II promoter involved in response to cadmium ion stress|up-regulation of global transcription from RNA polymerase II promoter involved in response to cadmium toxicity|upregulation of transcription from RNA polymerase II promoter involved in stress response to cadmium ion|stimulation of transcription from RNA polymerase II promoter involved in stress response to cadmium ion|activation of global transcription from RNA polymerase II promoter involved in response to cadmium ion stress							kmv	2014-04-14T18:03:42Z					biological_process											owl:Class	
GO:0071004	biolink:NamedThing	U2-type prespliceosome	A spliceosomal complex that is formed by association of the 5' splice site with the U1 snRNP, while the branch point sequence is recognized by the U2 snRNP. The prespliceosome includes many proteins in addition to those found in the U1 and U2 snRNPs. Commitment to a given pair of 5' and 3' splice sites occurs at the time of prespliceosome formation.	tmpzr1t_l9r_go_relaxed.owl	yeast U2-type spliceosomal complex B|mammalian U2-type spliceosomal complex A|GT-AG prespliceosome|major prespliceosome							mah	2009-07-30T12:00:35Z					cellular_component											owl:Class	
GO:1900320	biolink:NamedThing	positive regulation of methane biosynthetic process from dimethylamine	Any process that activates or increases the frequency, rate or extent of methane biosynthetic process from dimethylamine.	tmpzr1t_l9r_go_relaxed.owl	upregulation of methane biosynthetic process from dimethylamine|up-regulation of methane biosynthetic process from dimethylamine|up regulation of methane biosynthetic process from dimethylamine|activation of methane biosynthetic process from dimethylamine							tt	2012-04-06T01:43:40Z					biological_process											owl:Class	
GO:1904382	biolink:NamedThing	mannose trimming involved in glycoprotein ERAD pathway	The removal of one or more alpha 1,2-linked mannose residues from a mannosylated protein that occurs as part of glycoprotein ER-associated glycoprotein degradation (gpERAD).	tmpzr1t_l9r_go_relaxed.owl	glycoprotein mannose trimming involved in gpERAD|glycoprotein mannose trimming involved in glycoprotein ERAD|protein alpha-1,2-demannosylation involved in gpERAD|protein alpha-1,2-demannosylation involved in glycoprotein ERAD|glycoprotein mannose trimming involved in glycoprotein ERAD pathway|mannose trimming involved in misfolded or incompletely synthesized glycoprotein catabolic process|protein alpha-1,2-demannosylation involved in ER-associated glycoprotein degradation|glycoprotein mannose trimming involved in ER-associated glycoprotein degradation|protein alpha-1,2-demannosylation involved in glycoprotein ERAD pathway							bf	2015-06-23T09:46:55Z					biological_process											owl:Class	
GO:0035977	biolink:NamedThing	protein deglycosylation involved in glycoprotein catabolic process	The removal of sugar residues from a glycosylated protein that contributes to the breakdown of a glycoprotein.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-08-18T10:31:23Z					biological_process											owl:Class	
GO:0008556	biolink:NamedThing	P-type potassium transmembrane transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + K+(out) = ADP + phosphate + K+(in).	tmpzr1t_l9r_go_relaxed.owl	potassium transmembrane transporter activity, phosphorylative mechanism|K(+)-transporting ATPase activity|K+-transporting ATPase activity|potassium ABC transporter|K+-importing ATPase activity|ATPase-coupled potassium transmembrane transporter activity|ATP phosphohydrolase (K+-importing)|ATP-dependent potassium transmembrane transporter activity|potassium-uptake-ATPase activity|K(+)-importing ATPase activity|potassium-transporting ATPase activity|potassium-importing ATPase activity|potassium transporting ATPase activity				EC:7.2.2.6|RHEA:16777							GO:0015618		molecular_function											owl:Class	
GO:0010201	biolink:NamedThing	response to continuous far red light stimulus by the high-irradiance response system	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the detection of a continuous far red light stimulus by the high-irradiance response system. Far red light is electromagnetic radiation of wavelength 700-800nm. The activity of the high-irradiance response system is characterized by stronger effects of continuous than pulsed light at equal total fluence.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0018655	biolink:NamedThing	2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA 1,2-monooxygenase activity	Catalysis of the reaction: 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA + NADH + H+ + O2 = NAD+ + H2O + delta2,5-3,4,4-trimethylpimelyl-CoA.	tmpzr1t_l9r_go_relaxed.owl					EC:1.14.13.-|UM-BBD_reactionID:r0430									molecular_function											owl:Class	
GO:0090417	biolink:NamedThing	N-methylnicotinate transmembrane transporter activity	Enables the transfer of N-methylnicotinate from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	N-methylnicotinate transporter activity							tb	2011-10-19T11:09:59Z					molecular_function											owl:Class	
GO:0071037	biolink:NamedThing	nuclear polyadenylation-dependent snRNA catabolic process	The chemical reactions and pathways occurring in the nucleus and resulting in the breakdown of a small nuclear RNA (snRNA) molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target snRNA.	tmpzr1t_l9r_go_relaxed.owl	nuclear poly(A)-dependent snRNA catabolic process							krc	2009-07-29T01:07:18Z					biological_process											owl:Class	
GO:0032772	biolink:NamedThing	negative regulation of tyrosinase activity	Any process that stops or reduces the activity of a tyrosinase enzyme.	tmpzr1t_l9r_go_relaxed.owl	down regulation of monophenol oxygenase activity|down-regulation of monophenol oxygenase activity|negative regulation of monophenol oxygenase activity|downregulation of monophenol oxygenase activity|inhibition of monophenol oxygenase activity|negative regulation of monophenol monooxygenase activity	https://github.com/geneontology/go-ontology/issues/21024												biological_process											owl:Class	
GO:1905271	biolink:NamedThing	regulation of proton-transporting ATP synthase activity, rotational mechanism	Any process that modulates the frequency, rate or extent of proton-transporting ATP synthase activity, rotational mechanism.	tmpzr1t_l9r_go_relaxed.owl	regulation of hydrogen ion translocating F-type ATPase activity|regulation of hydrogen ion transporting two-sector ATPase activity|regulation of H+-transporting ATP synthase activity|regulation of hydrogen ion transporting ATP synthase activity, rotational mechanism							als	2016-06-16T12:09:49Z					biological_process											owl:Class	
GO:0030560	biolink:NamedThing	tRNA pseudouridylation guide activity	Specifies the site of pseudouridylation in a tRNA molecule by base pairing with a short sequence around the target residue.	tmpzr1t_l9r_go_relaxed.owl						Note that this term describes the activity of a nucleic acid, usually RNA, gene product that interacts with other RNA molecules via base pairing; it should not be used to annotate proteins.								molecular_function											owl:Class	
GO:0018189	biolink:NamedThing	pyrroloquinoline quinone biosynthetic process	The chemical reactions and pathways resulting in the formation of the cofactor pyrroloquinoline quinone (PQQ); it is synthesized from a small peptide containing tyrosine and glutamic acid; these amino acids in the peptide are multiply cross-linked and the rest of the peptide is removed.	tmpzr1t_l9r_go_relaxed.owl	coenzyme pyrroloquinoline-quinone biosynthetic process|pyrroloquinoline-quinone biosynthesis|pyrroloquinoline quinone synthesis|PQQ biosynthesis|coenzyme pyrroloquinoline-quinone biosynthesis|PQQ biosynthetic process|pyrroloquinoline quinone anabolism|pyrroloquinoline quinone formation|pyrroloquinoline quinone biosynthesis|pyrroloquinoline-quinone biosynthetic process	https://github.com/geneontology/go-ontology/issues/20547			RESID:AA0283									biological_process											owl:Class	
GO:0042292	biolink:NamedThing	URM1 activating enzyme activity	Catalysis of the activation of the small ubiquitin-related modifier URM1, through the formation of an ATP-dependent high-energy thiolester bond.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0061862	biolink:NamedThing	cellular response to differentiation-inducing factor 2	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)pentan-1-one stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)pentan-1-one|cellular response to DIF2|cellular response to DIF-2							dph	2017-04-07T17:14:16Z					biological_process											owl:Class	
GO:0006772	biolink:NamedThing	thiamine metabolic process	The chemical reactions and pathways involving thiamine (vitamin B1), a water soluble vitamin present in fresh vegetables and meats, especially liver.	tmpzr1t_l9r_go_relaxed.owl	thiamin metabolic process|vitamin B1 metabolism|thiamin metabolism|vitamin B1 metabolic process|thiamine metabolism				Wikipedia:Thiamine									biological_process											owl:Class	
GO:0018076	biolink:NamedThing	N-terminal peptidyl-lysine acetylation	The acetylation of the N-terminal lysine of proteins.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0033418	biolink:NamedThing	CUC codon-amino acid adaptor activity	A triplet codon-amino acid adaptor activity that recognizes a CUC codon.	tmpzr1t_l9r_go_relaxed.owl	leucine tRNA|CTC codon-amino acid adaptor activity					Note that in the standard genetic code, CTC codes for leucine.								molecular_function											owl:Class	
GO:0097313	biolink:NamedThing	bacterial biofilm matrix surface	The external part of the biofilm matrix, a structure lying external to bacterial cells. A biofilm is an aggregate of surface-associated bacteria, and the biofilm matrix is the envelope of polymeric substances that surrounds the bacteria.	tmpzr1t_l9r_go_relaxed.owl								pr	2012-05-24T11:25:47Z					cellular_component											owl:Class	
GO:0042600	biolink:NamedThing	egg chorion	A protective, noncellular membrane that surrounds the eggs of various animals including insects and fish.	tmpzr1t_l9r_go_relaxed.owl						Note that this term does not refer to the extraembryonic membrane surrounding the embryo of amniote vertebrates as this is an anatomical structure and is therefore not covered by GO.								cellular_component											owl:Class	
GO:0030312	biolink:NamedThing	external encapsulating structure	A structure that lies outside the plasma membrane and surrounds the entire cell or cells. This does not include the periplasmic space.	tmpzr1t_l9r_go_relaxed.owl						The outer membrane (of gram negative bacteria) or cell wall (of yeast or Gram positive bacteria) are defined as parts of this structure, see 'external encapsulating structure part'.								cellular_component											owl:Class	
GO:0008741	biolink:NamedThing	ribulokinase activity	Catalysis of the reaction: ATP + L(or D)-ribulose = ADP + L(or D)-ribulose 5-phosphate.	tmpzr1t_l9r_go_relaxed.owl	ribulokinase (phosphorylating)|ATP:L(or D)-ribulose 5-phosphotransferase activity|L-ribulokinase activity				MetaCyc:RIBULOKIN-RXN|EC:2.7.1.16|RHEA:22072									molecular_function											owl:Class	
GO:0102207	biolink:NamedThing	docosanoate omega-hydroxylase activity	Catalysis of the reaction: docosanoate + O2 + reduced [NADPH--hemoprotein reductase] = 22-hydroxydocosanoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase].	tmpzr1t_l9r_go_relaxed.owl	behenate omega-hydroxylase activity	https://github.com/geneontology/go-ontology/issues/19925			RHEA:40079|MetaCyc:RXN-12155									molecular_function											owl:Class	
GO:0120250	biolink:NamedThing	fatty acid omega-hydroxylase activity	Catalysis of the reaction: an omega-methyl fatty acid + O2 + reduced [NADPH--hemoprotein reductase] = an omega-hydroxy fatty acid + H(+) + H2O + oxidized [NADPH--hemoprotein reductase].	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/19899			RHEA:39023			krc	2020-09-01T00:19:13Z					molecular_function											owl:Class	
GO:1901252	biolink:NamedThing	regulation of intracellular transport of viral material	Any process that modulates the frequency, rate or extent of egress of virus within host cell.	tmpzr1t_l9r_go_relaxed.owl	regulation of egress of virus within host cell|regulation of movement of virus within host cell|regulation of viral egress							ss	2012-08-09T05:45:25Z					biological_process											owl:Class	
GO:1990657	biolink:NamedThing	iNOS-S100A8/A9 complex	A protein complex capable of stimulus-inducible nitric-oxide synthase activity. S-nitrosylates cysteine residues in target proteins, a principal mechanism of nitric oxide (NO)-mediated signal transduction. In mammals consists of NOS2, S100A8 and S100A9. S100A9 acts both as an adaptor linking NOS2 to its target and as a transnitrosylase that transfers the nitric oxide moiety from NOS2 to its target, via its own S-nitrosylated cysteine.	tmpzr1t_l9r_go_relaxed.owl						An example of this is NOS2 in human (UniProt symbol P35228) in PMID:25417112 (inferred from direct assay).		bhm	2015-02-25T11:00:49Z					cellular_component											owl:Class	
GO:1903958	biolink:NamedThing	nitric-oxide synthase complex	A protein complex which is capable of nitric-oxide synthase activity.	tmpzr1t_l9r_go_relaxed.owl	iNOS-S100A8/A9 complex					An example of this is NOS2 in human (P35228) in PMID:25417112 (inferred from direct assay).		bhm	2015-02-25T10:45:01Z					cellular_component											owl:Class	
GO:0005096	biolink:NamedThing	GTPase activator activity	Binds to and increases the activity of a GTPase, an enzyme that catalyzes the hydrolysis of GTP.	tmpzr1t_l9r_go_relaxed.owl	Rho GTPase activator activity|Rap GTPase activator activity|Ran GAP activity|Rac GTPase activator activity|Ras GAP activity|Sar GTPase activator activity|Rac GAP activity|Sar GAP activity|ARF GTPase activator activity|GAP activity|Ral GTPase activator activity|Ran GTPase activator activity|Rho GAP activity|Rab GAP activity|Ral GAP activity|Rap GAP activity|ARF GAP activity|RanGAP|Rab GTPase activator activity|Ras GTPase activator activity				Reactome:R-HSA-416546|Reactome:R-HSA-416559|Reactome:R-HSA-428533|Reactome:R-HSA-4093339|Reactome:R-HSA-9624893|Reactome:R-HSA-392513|Reactome:R-HSA-399935|Reactome:R-HSA-5638007|Reactome:R-HSA-194922|Reactome:R-HSA-428522|Reactome:R-HSA-8985594	Note that the name Sar derives from 'secretion-associated, Ras-related'.						GO:0005100|GO:0005101|GO:0008060|GO:0046582|GO:0005097|GO:0030675|GO:0005099|GO:0005098|GO:0017123		molecular_function											owl:Class	
GO:0046085	biolink:NamedThing	adenosine metabolic process	The chemical reactions and pathways involving adenosine, adenine riboside, a ribonucleoside found widely distributed in cells of every type as the free nucleoside and in combination in nucleic acids and various nucleoside coenzymes.	tmpzr1t_l9r_go_relaxed.owl	adenosine metabolism													biological_process											owl:Class	
GO:0008273	biolink:NamedThing	calcium, potassium:sodium antiporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Ca2+(in) + K+(in) + Na+(out) = Ca2+(out) + K+(out) + Na+(in).	tmpzr1t_l9r_go_relaxed.owl	potassium-dependent sodium/calcium exchanger				Reactome:R-HSA-2514891|Reactome:R-HSA-5626316|Reactome:R-HSA-5626356|Reactome:R-HSA-5626270|Reactome:R-HSA-5625841|Reactome:R-HSA-425678									molecular_function											owl:Class	
GO:0022821	biolink:NamedThing	potassium ion antiporter activity	Catalysis of the active transport of a potassium ion across a membrane by a mechanism whereby two or more species are transported in opposite directions in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0098938	biolink:NamedThing	actin cytoskeleton of dendritic spine	The actin cytoskeleton that is part of a dendritic spine.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0015720	biolink:NamedThing	allantoin transport	The directed movement of allantoin, (2,5-dioxo-4-imidazolidinyl)urea, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	allantoin/allantoate transport|allantoin transmembrane transport													biological_process											owl:Class	
GO:0003156	biolink:NamedThing	regulation of animal organ formation	Any process that modulates the rate, frequency or extent of animal organ formation. Organ formation is the process pertaining to the initial formation of an organ from unspecified parts. The process begins with the specific processes that contribute to the appearance of the discrete structure, such as inductive events, and ends when the structural rudiment of the organ is recognizable, such as a condensation of mesenchymal cells into the organ rudiment.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-09-30T11:21:09Z					biological_process											owl:Class	
GO:0051080	biolink:NamedThing	meiosis II nuclear membrane disassembly	The controlled breakdown of the nuclear membranes during the second division of meiosis.	tmpzr1t_l9r_go_relaxed.owl	meiosis II nuclear envelope disassembly|meiosis II nuclear envelope degradation|meiosis II nuclear envelope catabolism|meiosis II nuclear envelope breakdown													biological_process											owl:Class	
GO:0061660	biolink:NamedThing	Atg12 ligase activity	Catalysis of the transfer of Atg12 to a substrate protein via the reaction X-Atg12 + S --> X + S-Atg12, where X is either an E2 or E3 enzyme, the X-Atg12 linkage is a thioester bond, and the S-Atg12 linkage is an isopeptide bond between the C-terminal amino acid of Atg12 and the epsilon-amino group of lysine residues in the substrate.	tmpzr1t_l9r_go_relaxed.owl	E3							dph	2014-11-06T13:50:42Z					molecular_function											owl:Class	
GO:0019777	biolink:NamedThing	Atg12 transferase activity	Catalysis of the transfer of ATG12 from one protein to another via the reaction X-ATG12 + Y --> Y-ATG12 + X, where both X-ATG12 and Y-ATG12 are covalent linkages.	tmpzr1t_l9r_go_relaxed.owl	Atg12 conjugating enzyme activity|APG12 conjugating enzyme activity|APG12 ligase activity|Atg12 ligase activity				Reactome:R-HSA-5681999									molecular_function											owl:Class	
GO:0010361	biolink:NamedThing	regulation of anion channel activity by blue light	Any process in which blue light modulates the frequency, rate or extent of anion channel activity.	tmpzr1t_l9r_go_relaxed.owl	regulation by blue light of anion channel activity													biological_process											owl:Class	
GO:0052667	biolink:NamedThing	phosphomethylethanolamine N-methyltransferase activity	Catalysis of the reaction: N-methylethanolamine phosphate + S-adenosyl-L-methionine = N,N-dimethylethanolamine phosphate + S-adenosyl-L-homocysteine + H(+).	tmpzr1t_l9r_go_relaxed.owl	S-adenosyl-L-methionine:methylethanolamine phosphate N-methyltransferase activity|N-methylethanolamine phosphate N-methyltransferase activity				KEGG_REACTION:R06868|RHEA:25321|MetaCyc:RXN-5642|EC:2.1.1.103			ai	2011-04-11T11:36:47Z					molecular_function											owl:Class	
GO:0106148	biolink:NamedThing	4-hydroxyindole-3- carbonyl nitrile biosynthesis	The chemical reactions and pathways resulting in the formation of 4-hydroxyindole-3- carbonyl nitrile (4-OH-ICN), a cyanogenic glucoside.	tmpzr1t_l9r_go_relaxed.owl								hjd	2018-09-10T19:42:16Z					biological_process											owl:Class	
GO:0102788	biolink:NamedThing	4-coumaroyl-CoA:pelargonidin-3-O-beta-D-glucoside-6''-O-acyltransferase activity	Catalysis of the reaction: 4-coumaryl-CoA + pelargonidin 3-O-beta-D-glucoside = pelargonidin 3-O-beta-D-p-coumaroylglucoside + coenzyme A.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-7998									molecular_function											owl:Class	
GO:0006625	biolink:NamedThing	protein targeting to peroxisome	The process of directing proteins towards the peroxisome, usually using signals contained within the protein.	tmpzr1t_l9r_go_relaxed.owl	protein-peroxisome targeting													biological_process											owl:Class	
GO:0043574	biolink:NamedThing	peroxisomal transport	Transport of substances into, out of or within a peroxisome, a small, membrane-bounded organelle that uses dioxygen (O2) to oxidize organic molecules.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0060267	biolink:NamedThing	positive regulation of respiratory burst	Any process that increases the rate frequency or extent of a phase of elevated metabolic activity, during which oxygen consumption increases; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0018029	biolink:NamedThing	peptidyl-lysine palmitoylation	The palmitoylation of peptidyl-lysine to form peptidyl-N6-palmitoyl-L-lysine.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0077									biological_process											owl:Class	
GO:0048352	biolink:NamedThing	paraxial mesoderm structural organization	The process that contributes to the act of creating the structural organization of the paraxial mesoderm. This process pertains to the physical shaping of a rudimentary structure.	tmpzr1t_l9r_go_relaxed.owl	paraxial mesoderm structural organisation													biological_process											owl:Class	
GO:0046625	biolink:NamedThing	sphingolipid binding	Binding to a sphingolipid, a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid).	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1902132	biolink:NamedThing	(+)-lariciresinol biosynthetic process	The chemical reactions and pathways resulting in the formation of (+)-lariciresinol.	tmpzr1t_l9r_go_relaxed.owl	(+)-lariciresinol formation|(+)-lariciresinol biosynthesis|(+)-lariciresinol synthesis|(+)-lariciresinol anabolism							ms	2013-05-21T08:49:59Z					biological_process											owl:Class	
GO:0071273	biolink:NamedThing	morphine catabolic process	The chemical reactions and pathways resulting in the breakdown of morphine, 17-methyl-7,8-didehydro-4,5alpha-epoxymorphinan-3,6alpha-diol. Morphine is a highly potent opiate analgesic psychoactive drug obtained form the opium poppy, Papaver somniferum.	tmpzr1t_l9r_go_relaxed.owl	morphine degradation|morphine catabolism|morphine breakdown				UniPathway:Q02198			mah	2009-12-10T11:16:28Z					biological_process											owl:Class	
GO:0102672	biolink:NamedThing	fatty acid alpha-oxygenase activity	Catalysis of the reaction: O2 + a 2,3,4-saturated fatty acid <=> a 2(R)-hydroperoxy fatty acid.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-4121									molecular_function											owl:Class	
GO:0046506	biolink:NamedThing	sulfolipid biosynthetic process	The chemical reactions and pathways resulting in the formation of sulfolipid, a compound containing a sulfonic acid residue joined by a carbon-sulfur bond to a lipid.	tmpzr1t_l9r_go_relaxed.owl	sulfolipid formation|sulfolipid synthesis|sulfolipid biosynthesis|sulpholipid biosynthetic process|sulpholipid biosynthesis|sulfolipid anabolism													biological_process											owl:Class	
GO:0015208	biolink:NamedThing	guanine transmembrane transporter activity	Enables the transfer of guanine, 2-amino-6-hydroxypurine, from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1900552	biolink:NamedThing	asperfuranone metabolic process	The chemical reactions and pathways involving asperfuranone.	tmpzr1t_l9r_go_relaxed.owl	asperfuranone metabolism							di	2012-05-15T01:30:48Z					biological_process											owl:Class	
GO:0007545	biolink:NamedThing	processes downstream of sex determination signal	The sex determination processes that take place after the initial transmission of the sexual phenotype to specific information pathways.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0102868	biolink:NamedThing	24-epi-campsterol desaturase activity	Catalysis of the reaction: 24-epi-campesterol + NADPH + H+ + O2 <=> brassicasterol + NADP + 2 H2O.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-8352									molecular_function											owl:Class	
GO:1905175	biolink:NamedThing	negative regulation of vascular associated smooth muscle cell dedifferentiation	Any process that stops, prevents or reduces the frequency, rate or extent of vascular smooth muscle cell dedifferentiation.	tmpzr1t_l9r_go_relaxed.owl	downregulation of vascular smooth muscle cell dedifferentiation|negative regulation of vascular smooth muscle cell dedifferentiation|down regulation of vascular smooth muscle cell dedifferentiation|inhibition of vascular smooth muscle cell dedifferentiation|down-regulation of vascular smooth muscle cell dedifferentiation							rph	2016-05-03T12:32:05Z					biological_process											owl:Class	
GO:0102309	biolink:NamedThing	dTDP-4-oxo-2,6-dideoxy-D-glucose 4-ketoreductase (dTDP-D-oliose producing) activity	Catalysis of the reaction: dTDP-D-oliose + NADP <=> dTDP-4-dehydro-2,6-dideoxy-D-glucose + NADPH + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-12930									molecular_function											owl:Class	
GO:0140453	biolink:NamedThing	protein aggregate center	Reversible aggregate of misfolded proteins and chaperones formed to shield thermosensitive proteins from degradation until conditions allow disaggregation and refolding.	tmpzr1t_l9r_go_relaxed.owl	protein aggregate centre|PAC	https://github.com/geneontology/go-ontology/issues/19172						pg	2020-04-20T15:21:55Z					cellular_component											owl:Class	
GO:0015069	biolink:NamedThing	scyllo-inosamine-4-phosphate amidinotransferase activity	Catalysis of the reaction: 1-amino-1-deoxy-scyllo-inositol 4-phosphate + L-arginine = 1-guanidino-1-deoxy-scyllo-inositol 4-phosphate + L-ornithine.	tmpzr1t_l9r_go_relaxed.owl	inosamine-P amidinotransferase activity|inosamine-phosphate amidinotransferase activity|L-arginine:inosamine phosphate amidinotransferase activity|L-arginine:inosamine-P-amidinotransferase activity|L-arginine:1-amino-1-deoxy-scyllo-inositol-4-phosphate amidinotransferase activity				RHEA:13265|EC:2.1.4.2|KEGG_REACTION:R03477|MetaCyc:2.1.4.2-RXN									molecular_function											owl:Class	
GO:0010235	biolink:NamedThing	guard mother cell cytokinesis	The stereotyped symmetric cell division by which guard mother cell give rise to stomatal guard cells.	tmpzr1t_l9r_go_relaxed.owl	guard mother cell division													biological_process											owl:Class	
GO:0042192	biolink:NamedThing	methylmercury biosynthetic process	The chemical reactions and pathways resulting in the formation of methylmercury (MeHg+), a highly toxic organometal.	tmpzr1t_l9r_go_relaxed.owl	methylmercury formation|methylmercury synthesis|methylmercury anabolism|methylmercury biosynthesis													biological_process											owl:Class	
GO:0046414	biolink:NamedThing	organomercury biosynthetic process	The chemical reactions and pathways resulting in the formation of organomercury compounds, any organic compound containing a mercury atom.	tmpzr1t_l9r_go_relaxed.owl	organomercury formation|organomercury biosynthesis|organomercury anabolism|organomercury synthesis													biological_process											owl:Class	
GO:0090434	biolink:NamedThing	oleoyl-CoA ligase activity	Catalysis of the reaction: ATP + oleic acid + CoA = AMP + diphosphate + oleoyl-CoA.	tmpzr1t_l9r_go_relaxed.owl	oleoyl-CoA synthetase activity							tb	2012-07-25T03:31:31Z					molecular_function											owl:Class	
GO:0061698	biolink:NamedThing	protein deglutarylation	The removal of a glutaryl group (CO-CH2-CH2-CH2-CO) from a residue in a peptide or protein.	tmpzr1t_l9r_go_relaxed.owl								dph	2015-05-07T11:02:31Z					biological_process											owl:Class	
GO:0042630	biolink:NamedThing	behavioral response to water deprivation	Any process that results in a change in the behavior of an organism as a result of deprivation of water.	tmpzr1t_l9r_go_relaxed.owl	behavioural response to water deprivation|behavioral response to thirst|behavioral response to drought													biological_process											owl:Class	
GO:0010514	biolink:NamedThing	induction of conjugation with cellular fusion	The process in which a cell initiates conjugation with cellular fusion. Conjugation with cellular fusion is the process that results in the union of cellular and genetic information from compatible mating types.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0008946	biolink:NamedThing	oligonucleotidase activity	Catalysis of the exonucleolytic cleavage of oligonucleotides to yield nucleoside 5'-phosphates.	tmpzr1t_l9r_go_relaxed.owl					EC:3.1.13.3|MetaCyc:3.1.13.3-RXN	Note that enzymes with this activity usually also hydrolyze NAD+ to NMN and AMP.								molecular_function											owl:Class	
GO:0050595	biolink:NamedThing	7-deoxyloganin 7-hydroxylase activity	Catalysis of the reaction: 7-deoxyloganin + NADPH + H+ + O2 = loganin + NADP+ + H2O.	tmpzr1t_l9r_go_relaxed.owl	7-deoxyloganin,NADPH:oxygen oxidoreductase (7alpha-hydroxylating)				RHEA:11452|MetaCyc:1.14.13.74-RXN|EC:1.14.13.74									molecular_function											owl:Class	
GO:0021520	biolink:NamedThing	spinal cord motor neuron cell fate specification	The process in which a cell becomes capable of differentiating autonomously into a motor neuron in an environment that is neutral with respect to the developmental pathway.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0048665	biolink:NamedThing	neuron fate specification	The process in which a cell becomes capable of differentiating autonomously into a neuron in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1901783	biolink:NamedThing	p-cumate biosynthetic process	The chemical reactions and pathways resulting in the formation of p-cumate.	tmpzr1t_l9r_go_relaxed.owl	p-cumate synthesis|p-cumate anabolism|p-cumate biosynthesis|p-cumate formation							yaf	2013-01-16T10:40:36Z					biological_process											owl:Class	
GO:0050103	biolink:NamedThing	dextrin dextranase activity	Catalysis of the reaction: 1,4-alpha-D-glucosyl(n) + 1,6-alpha-D-glucosyl(m) = 1,4-alpha-D-glucosyl(n-1) + 1,6-alpha-D-glucosyl(m+1).	tmpzr1t_l9r_go_relaxed.owl	dextran dextrinase activity|dextrin 6-glucosyltransferase activity|1,4-alpha-D-glucan:1,6-alpha-D-glucan 6-alpha-D-glucosyltransferase activity				MetaCyc:DEXTRIN-DEXTRANASE-RXN|RHEA:14625|EC:2.4.1.2									molecular_function											owl:Class	
GO:0097411	biolink:NamedThing	hypoxia-inducible factor-1alpha signaling pathway	A series of molecular signals mediated by hypoxia-inducible factor (HIF1) in response to lowered oxygen levels (hypoxia). Under hypoxic conditions, the oxygen-sensitive alpha-subunit of hypoxia-inducible factor (HIF)-1 dimerizes with a HIF1-beta subunit (also called ARNT or aryl-hydrocarbon-receptor nuclear translocator), translocates to the nucleus and activates transcription of genes whose products participate in responding to hypoxia.	tmpzr1t_l9r_go_relaxed.owl	hypoxia-inducible factor signaling|HIF1alpha pathway|hypoxia-inducible factor-1alpha signalling pathway							pr	2012-11-06T10:46:33Z					biological_process											owl:Class	
GO:0050232	biolink:NamedThing	putrescine oxidase activity	Catalysis of the reaction: putrescine + O2 + H2O = 4-aminobutanal + NH3 + H2O2.	tmpzr1t_l9r_go_relaxed.owl	putrescine:oxygen oxidoreductase (deaminating)				EC:1.4.3.10|MetaCyc:PUTRESCINE-OXIDASE-RXN|RHEA:18273									molecular_function											owl:Class	
GO:1990670	biolink:NamedThing	vesicle fusion with Golgi cis cisterna membrane	The joining of the lipid bilayer membrane around a vesicle to the lipid bilayer membrane around the Golgi cis cisterna. This can involve anterograde or retrograde transport vesicles.	tmpzr1t_l9r_go_relaxed.owl								bhm	2015-03-02T11:25:19Z					biological_process											owl:Class	
GO:0140268	biolink:NamedThing	endoplasmic reticulum-plasma membrane contact site	A contact site between the endoplasmic reticulum membrane and the plasma membrane, structured by bridging complexes.	tmpzr1t_l9r_go_relaxed.owl	ER-plasma membrane contact site|EPCS|ER-PM contact site|endoplasmic reticulum-plasma membrane contact junction							pg	2018-09-26T09:29:41Z					cellular_component											owl:Class	
GO:0021938	biolink:NamedThing	smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation	The series of molecular signals generated as a consequence of activation of the transmembrane protein Smoothened in cerebellar granule cells that contributes to the regulation of proliferation of the cells.	tmpzr1t_l9r_go_relaxed.owl	hh signaling pathway involved in regulation of granule cell precursor cell proliferation|smoothened signalling pathway in regulation of granule cell precursor cell proliferation|hedgehog signaling pathway involved in regulation of granule cell precursor cell proliferation													biological_process											owl:Class	
GO:0018267	biolink:NamedThing	GPI anchor biosynthetic process via N-cysteinyl-glycosylphosphatidylinositolethanolamine	The chemical reactions and pathways resulting in the formation of a C-terminal peptidyl-cysteine ethanolamide-linked glycosylphosphatidylinositol (GPI) anchor following hydrolysis of a cysteinyl-peptide bond in the carboxy-terminal region of a membrane-associated protein.	tmpzr1t_l9r_go_relaxed.owl	GPI anchor formation via N-cysteinyl-glycosylphosphatidylinositolethanolamine|GPI anchor synthesis via N-cysteinyl-glycosylphosphatidylinositolethanolamine|GPI anchor anabolism via N-cysteinyl-glycosylphosphatidylinositolethanolamine				RESID:AA0160									biological_process											owl:Class	
GO:0043024	biolink:NamedThing	ribosomal small subunit binding	Binding to a small ribosomal subunit.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0102190	biolink:NamedThing	4alpha-formyl-5alpha-cholesta-7,24-dien-3beta-ol-4alpha-methyl oxidase activity	Catalysis of the reaction: 4alpha-formyl-5alpha-cholesta-7,24-dien-3beta-ol + O2 + NADH(2-) <=> 4alpha-carboxy-5alpha-cholesta-7,24-dien-3beta-ol + NAD(1-) + H2O.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-11958									molecular_function											owl:Class	
GO:0097067	biolink:NamedThing	cellular response to thyroid hormone stimulus	A change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a thyroid hormone stimulus.	tmpzr1t_l9r_go_relaxed.owl								pr	2011-06-14T05:02:47Z					biological_process											owl:Class	
GO:0140225	biolink:NamedThing	DNA topoisomerase III-beta-TDRD3 complex	A protein complex that has DNA topoisomerase type I and RNA topoisomerase activities.	tmpzr1t_l9r_go_relaxed.owl	Top3-beta-TDRD3 complex							pg	2018-05-29T10:05:33Z					cellular_component											owl:Class	
GO:0003150	biolink:NamedThing	muscular septum morphogenesis	The process in which the muscular septum is generated and organized. The muscular septum is the lower part of the ventricular septum.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-09-22T07:53:28Z					biological_process											owl:Class	
GO:0007534	biolink:NamedThing	gene conversion at mating-type locus	The conversion of the mating-type locus from one allele to another resulting from the recombinational repair of a site-specific double-strand break at the mating-type locus with information from a silent donor sequence. There is no reciprocal exchange of information because the mating-type locus copies information from the donor sequence and the donor sequence remains unchanged.	tmpzr1t_l9r_go_relaxed.owl	gene conversion at mating-type locus, DNA repair synthesis|gene conversion at mating-type locus, DNA double-strand break processing|heteroduplex formation involved in gene conversion at mating-type locus|gene conversion at mating-type locus, termination of copy-synthesis|gene conversion at mating-type locus, DNA double-strand break formation|strand invasion involved in gene conversion at mating-type locus	https://github.com/geneontology/go-ontology/issues/19999										GO:0010708|GO:0034636|GO:0000728|GO:0000734|GO:0031292|GO:0061500		biological_process											owl:Class	
GO:1901958	biolink:NamedThing	negative regulation of cutin biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of cutin biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of cutin formation|down-regulation of cutin synthesis|down regulation of cutin biosynthesis|negative regulation of cutin biosynthesis|negative regulation of cutin synthesis|down-regulation of cutin formation|inhibition of cutin formation|inhibition of cutin biosynthesis|down regulation of cutin formation|down regulation of cutin anabolism|inhibition of cutin synthesis|down-regulation of cutin biosynthesis|downregulation of cutin synthesis|downregulation of cutin biosynthetic process|inhibition of cutin anabolism|down-regulation of cutin biosynthetic process|negative regulation of cutin anabolism|down regulation of cutin synthesis|downregulation of cutin formation|down regulation of cutin biosynthetic process|down-regulation of cutin anabolism|downregulation of cutin biosynthesis|downregulation of cutin anabolism|inhibition of cutin biosynthetic process							tb	2013-02-19T19:06:10Z					biological_process											owl:Class	
GO:1901957	biolink:NamedThing	regulation of cutin biosynthetic process	Any process that modulates the frequency, rate or extent of cutin biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of cutin biosynthesis|regulation of cutin synthesis|regulation of cutin formation|regulation of cutin anabolism							tb	2013-02-19T19:06:06Z					biological_process											owl:Class	
GO:0031221	biolink:NamedThing	arabinan metabolic process	The chemical reactions and pathways involving arabinan, a polysaccharide composed of arabinose residues.	tmpzr1t_l9r_go_relaxed.owl	arabinan metabolism													biological_process											owl:Class	
GO:0048841	biolink:NamedThing	regulation of axon extension involved in axon guidance	Any process that modulates the frequency, rate or extent of axon extension involved in axon guidance.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0030516	biolink:NamedThing	regulation of axon extension	Any process that modulates the rate, direction or extent of axon extension.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0035605	biolink:NamedThing	peptidyl-cysteine S-nitrosylase activity	Catalysis of the transfer of a nitric oxide (NO) group to a sulphur atom within a cysteine residue of a protein.	tmpzr1t_l9r_go_relaxed.owl	protein nitrosylase activity|S-nitrosylase activity					This term should not be used to annotate the nitrosylating action of nitric oxide synthase (NOS) if the nitroso group is synthesized directly on the substrate.		bf	2010-11-16T09:49:26Z					molecular_function											owl:Class	
GO:1900226	biolink:NamedThing	negative regulation of NLRP3 inflammasome complex assembly	Any process that stops, prevents or reduces the frequency, rate or extent of NLRP3 inflammasome complex assembly.	tmpzr1t_l9r_go_relaxed.owl	down regulation of NALP3 inflammasome complex assembly|downregulation of NLRP3 inflammasome complex assembly|down-regulation of NLRP3 inflammasome activation|negative regulation of NLRP3 inflammasome activation|down regulation of NLRP3 inflammasome activation|downregulation of NALP3 inflammasome complex assembly|down-regulation of NLRP3 inflammasome complex assembly|inhibition of NLRP3 inflammasome activation|inhibition of NALP3 inflammasome complex assembly|negative regulation of NALP3 inflammasome complex assembly|downregulation of NLRP3 inflammasome activation|down regulation of NLRP3 inflammasome complex assembly|down-regulation of NALP3 inflammasome complex assembly|inhibition of NLRP3 inflammasome complex assembly							jl	2012-03-22T04:18:24Z					biological_process											owl:Class	
GO:0018489	biolink:NamedThing	vanillate monooxygenase activity	Catalysis of the reaction: H(+) + NADH + O(2) + vanillate = 3,4-dihydroxybenzoate + formaldehyde + H(2)O + NAD(+).	tmpzr1t_l9r_go_relaxed.owl	vanillate:oxygen oxidoreductase (demethylating)|vanillate demethylase (aerobic) activity|vanillate demethylase activity|4-hydroxy-3-methoxybenzoate demethylase activity				MetaCyc:RXN-2|MetaCyc:RXN-10891|RHEA:13021|EC:1.14.13.82|UM-BBD_reactionID:r0146|KEGG_REACTION:R05274	Note that this was EC:1.2.3.12.								molecular_function											owl:Class	
GO:0032451	biolink:NamedThing	demethylase activity	Catalysis of the removal of a methyl group from a substrate.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1990792	biolink:NamedThing	cellular response to glial cell derived neurotrophic factor	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glial cell derived neurotrophic factor stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to astrocyte-derived trophic factor|cellular response to GDNF|cellular response to ATF							sl	2015-07-06T15:27:38Z					biological_process											owl:Class	
GO:1990790	biolink:NamedThing	response to glial cell derived neurotrophic factor	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glial cell derived neurotrophic factor stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to ATF|response to GDNF|response to astrocyte-derived trophic factor							sl	2015-07-02T19:47:05Z					biological_process											owl:Class	
GO:1904938	biolink:NamedThing	planar cell polarity pathway involved in axon guidance	Any Wnt signaling pathway, planar cell polarity pathway that is involved in axon guidance.	tmpzr1t_l9r_go_relaxed.owl	PCP pathway involved in axon growth cone guidance|Wnt receptor signalling pathway, planar cell polarity pathway involved in axon growth cone guidance|PCP pathway involved in axon pathfinding|Wnt signaling pathway, planar cell polarity pathway involved in axon growth cone guidance|Wnt-JNK signaling pathway involved in axon guidance|Wnt-PCP signaling pathway involved in axon guidance|planar cell polarity pathway involved in axon growth cone guidance|PCP pathway involved in axon guidance|Wnt receptor signaling pathway, planar cell polarity pathway involved in axon guidance|Wnt-activated signaling pathway, planar cell polarity pathway involved in axon chemotaxis|Wnt-JNK signaling pathway involved in axon chemotaxis|Wnt-PCP signaling pathway involved in axon growth cone guidance|Wnt receptor signaling pathway, planar cell polarity pathway involved in axon growth cone guidance|Wnt signaling pathway, planar cell polarity pathway involved in axon chemotaxis|Wnt-PCP signaling pathway involved in axon pathfinding|Wnt-activated signaling pathway, planar cell polarity pathway involved in axon guidance|non-canonical Wnt signaling pathway involved in axon guidance|planar cell polarity pathway involved in axon chemotaxis|planar cell polarity pathway involved in axon pathfinding|Wnt receptor signaling pathway, planar cell polarity pathway involved in axon chemotaxis|Wnt-activated signaling pathway, planar cell polarity pathway involved in axon pathfinding|Wnt receptor signaling pathway, planar cell polarity pathway involved in axon pathfinding|Wnt signaling pathway, planar cell polarity pathway involved in axon pathfinding|Wnt receptor signalling pathway, planar cell polarity pathway involved in axon chemotaxis|Wnt signaling pathway, planar cell polarity pathway involved in axon guidance|non-canonical Wnt signaling pathway involved in axon chemotaxis|Wnt-PCP signaling involved in axon guidance|Wnt receptor signalling pathway, planar cell polarity pathway involved in axon pathfinding|PCP pathway involved in axon chemotaxis|Wnt-JNK signaling pathway involved in axon pathfinding|non-canonical Wnt signaling pathway involved in axon growth cone guidance|Wnt-JNK signaling pathway involved in axon growth cone guidance|Wnt receptor signalling pathway, planar cell polarity pathway involved in axon guidance|Wnt-PCP signaling pathway involved in axon chemotaxis|non-canonical Wnt signaling pathway involved in axon pathfinding|Wnt-activated signaling pathway, planar cell polarity pathway involved in axon growth cone guidance							bf	2016-02-02T14:46:26Z					biological_process											owl:Class	
GO:0031359	biolink:NamedThing	integral component of chloroplast outer membrane	The component of the chloroplast outer membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.	tmpzr1t_l9r_go_relaxed.owl	integral to chloroplast outer membrane													cellular_component											owl:Class	
GO:0007566	biolink:NamedThing	embryo implantation	Attachment of the blastocyst to the uterine lining.	tmpzr1t_l9r_go_relaxed.owl	blastocyst implantation													biological_process											owl:Class	
GO:0046789	biolink:NamedThing	host cell surface receptor binding	Binding to a receptor on the host cell surface.	tmpzr1t_l9r_go_relaxed.owl	cell surface antigen activity, host-interacting|cell surface receptor ligand													molecular_function											owl:Class	
GO:0070200	biolink:NamedThing	establishment of protein localization to telomere	The directed movement of a protein to a specific location in the telomeric region of a chromosome.	tmpzr1t_l9r_go_relaxed.owl	establishment of protein localization to chromosome, telomeric region|establishment of protein localisation to telomere													biological_process											owl:Class	
GO:0072313	biolink:NamedThing	metanephric glomerular epithelial cell development	The process whose specific outcome is the progression of a metanephric glomerular epithelial cell over time, from its formation to the mature structure. Metanephric glomerular epithelial cells are specialized epithelial cells that form part of the metanephric glomerulus; there are two types, metanephric glomerular parietal epithelial cells and metanephric glomerular visceral epithelial cells.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-04-09T06:57:26Z					biological_process											owl:Class	
GO:0072312	biolink:NamedThing	metanephric glomerular epithelial cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a metanephric glomerular epithelial cell. Metanephric glomerular epithelial cells are specialized epithelial cells that form part of the metanephric glomerulus; there are two types, metanephric glomerular parietal epithelial cells and metanephric glomerular visceral epithelial cells.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-04-09T06:54:15Z					biological_process											owl:Class	
GO:0000055	biolink:NamedThing	ribosomal large subunit export from nucleus	The directed movement of a ribosomal large subunit from the nucleus into the cytoplasm.	tmpzr1t_l9r_go_relaxed.owl	ribosomal large subunit-nucleus export|ribosomal large subunit transport from nucleus to cytoplasm|60S ribosomal subunit export from nucleus|ribosomal large subunit export from cell nucleus|50S ribosomal subunit export from nucleus|ribosomal large subunit export out of nucleus											GO:0000057		biological_process											owl:Class	
GO:1902945	biolink:NamedThing	metalloendopeptidase activity involved in amyloid precursor protein catabolic process	Any metalloendopeptidase activity that is involved in amyloid precursor protein catabolic process.	tmpzr1t_l9r_go_relaxed.owl	metalloendoproteinase activity involved in APP catabolic process|metalloendopeptidase activity involved in APP catabolism|metalloendopeptidase activity involved in APP catabolic process|metalloendoprotease activity involved in amyloid precursor protein catabolic process|metalloendopeptidase activity involved in amyloid precursor protein catabolism|metalloendoprotease activity involved in APP catabolic process|metalloendoproteinase activity involved in amyloid precursor protein catabolism|metalloendopeptidase activity involved in amyloid precursor protein breakdown|metalloendoprotease activity involved in amyloid precursor protein catabolism|metalloendopeptidase activity involved in amyloid precursor protein degradation|metalloendoprotease activity involved in amyloid precursor protein degradation|metalloendoproteinase activity involved in amyloid precursor protein catabolic process|metalloendoprotease activity involved in amyloid precursor protein breakdown|metalloendoproteinase activity involved in amyloid precursor protein degradation|metalloendoproteinase activity involved in APP catabolism|metalloendoproteinase activity involved in amyloid precursor protein breakdown|metalloendoprotease activity involved in APP catabolism				Reactome:R-HSA-9010034			sjp	2014-05-02T08:13:04Z					molecular_function											owl:Class	
GO:0042987	biolink:NamedThing	amyloid precursor protein catabolic process	The chemical reactions and pathways resulting in the breakdown of amyloid precursor protein (APP), the precursor of amyloid-beta, a glycoprotein associated with Alzheimer's disease.	tmpzr1t_l9r_go_relaxed.owl	amyloid precursor protein catabolism|APP catabolic process|amyloid precursor protein degradation|amyloid precursor protein breakdown|APP catabolism													biological_process											owl:Class	
GO:1904336	biolink:NamedThing	negative regulation of ductus arteriosus closure	Any process that stops, prevents or reduces the frequency, rate or extent of ductus arteriosus closure.	tmpzr1t_l9r_go_relaxed.owl	down regulation of ductus arteriosus closure|inhibition of ductus arteriosus closure|downregulation of ductus arteriosus closure|down-regulation of ductus arteriosus closure							sl	2015-06-11T17:45:21Z					biological_process											owl:Class	
GO:0015918	biolink:NamedThing	sterol transport	The directed movement of sterols into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Sterols are steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0044496	biolink:NamedThing	negative regulation of blood pressure in other organism	A process by which one organism decreases the force with which blood travels through the circulatory system of another organism.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-02-01T02:15:28Z					biological_process											owl:Class	
GO:0045588	biolink:NamedThing	positive regulation of gamma-delta T cell differentiation	Any process that activates or increases the frequency, rate or extent of gamma-delta T cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of gamma-delta T cell development|upregulation of gamma-delta T cell differentiation|activation of gamma-delta T cell differentiation|positive regulation of gamma-delta T lymphocyte differentiation|positive regulation of gamma-delta T-cell differentiation|positive regulation of gamma-delta T-lymphocyte differentiation|up regulation of gamma-delta T cell differentiation|stimulation of gamma-delta T cell differentiation|up-regulation of gamma-delta T cell differentiation					Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.								biological_process											owl:Class	
GO:0032613	biolink:NamedThing	interleukin-10 production	The appearance of interleukin-10 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	tmpzr1t_l9r_go_relaxed.owl	interleukin-10 biosynthetic process|interleukin-10 secretion|IL-10 production											GO:0072608|GO:0042091		biological_process											owl:Class	
GO:0072265	biolink:NamedThing	metanephric capsule morphogenesis	The process in which the anatomical structures of the metanephric capsule are generated and organized. The metanephric capsule is the tough fibrous layer surrounding the metanephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-03-30T02:54:49Z					biological_process											owl:Class	
GO:0072213	biolink:NamedThing	metanephric capsule development	The process whose specific outcome is the progression of the metanephric capsule over time, from its formation to the mature structure. The metanephric capsule is the tough fibrous layer surrounding the metanephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-03-18T01:25:19Z					biological_process											owl:Class	
GO:0070268	biolink:NamedThing	cornification	A type of programmed cell death that occurs in the epidermis, morphologically and biochemically distinct from apoptosis. It leads to the formation of corneocytes, i.e. dead keratinocytes containing an amalgam of specific proteins (e.g., keratin, loricrin, SPR and involucrin) and lipids (e.g., fatty acids and ceramides), which are necessary for the function of the cornified skin layer (mechanical resistance, elasticity, water repellence and structural stability).	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0061080	biolink:NamedThing	right horn of sinus venosus development	The progression of the right horn of the sinus venosus from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-04-08T02:45:10Z					biological_process											owl:Class	
GO:0000943	biolink:NamedThing	retrotransposon nucleocapsid	A complex of the retrotransposon RNA genome, reverse transcriptase, integrase, and associated molecules required for reproduction and integration of the retrotransposon into the host genome; the main structural molecule of the nucleocapsid is often a gag protein homolog.	tmpzr1t_l9r_go_relaxed.owl	Virus-like particle|VLP				Wikipedia:Virus-like_particle									cellular_component											owl:Class	
GO:0009571	biolink:NamedThing	proplastid stroma	The space enclosed by the double membrane of a proplastid.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0032529	biolink:NamedThing	follicle cell microvillus organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a microvillus on a follicle cell. A microvillus is a thin cylindrical membrane-covered projection on the surface of an animal cell containing a core bundle of actin filaments.	tmpzr1t_l9r_go_relaxed.owl	follicle cell microvillus organization and biogenesis|follicle cell microvillus organisation													biological_process											owl:Class	
GO:0150035	biolink:NamedThing	regulation of trans-synaptic signaling by BDNF, modulating synaptic transmission	Any process that modulates the frequency, rate or extent of trans-synaptic signaling by BDNF, modulating synaptic transmission.	tmpzr1t_l9r_go_relaxed.owl						Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.		bc	2018-04-17T13:56:34Z					biological_process											owl:Class	
GO:0060047	biolink:NamedThing	heart contraction	The multicellular organismal process in which the heart decreases in volume in a characteristic way to propel blood through the body.	tmpzr1t_l9r_go_relaxed.owl	heart beating|cardiac contraction|hemolymph circulation													biological_process											owl:Class	
GO:1901044	biolink:NamedThing	protein polyubiquitination involved in nucleus-associated proteasomal ubiquitin-dependent protein catabolic process	Any protein polyubiquitination that is involved in nucleus-associated proteasomal ubiquitin-dependent protein catabolic process.	tmpzr1t_l9r_go_relaxed.owl								al	2012-06-26T10:59:04Z					biological_process											owl:Class	
GO:0060133	biolink:NamedThing	somatotropin secreting cell development	The process whose specific outcome is the progression of a somatotropin secreting cell over time, from its formation to the mature structure. A somatotropin secreting cell is an acidophilic cell of the anterior pituitary that produces growth hormone, somatotropin.	tmpzr1t_l9r_go_relaxed.owl	somatotrophin secreting cell development|somatotroph development|somatotropic cell development|somatotrope development|somatrophic cell development|growth hormone secreting cell development													biological_process											owl:Class	
GO:0043293	biolink:NamedThing	apoptosome	A multisubunit protein complex involved in the signaling phase of the apoptotic process. In mammals it is typically composed of seven Apaf-1 subunits bound to cytochrome c and caspase-9. A similar complex to promote apoptosis is formed from homologous gene products in other eukaryotic organisms.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Apoptosome									cellular_component											owl:Class	
GO:0007284	biolink:NamedThing	spermatogonial cell division	The mitotic divisions of the primary spermatogonial cell (a primordial male germ cell) to form secondary spermatogonia (primary spermatocytes).	tmpzr1t_l9r_go_relaxed.owl	spermatogonium division					See also the Cell Ontology terms 'spermatogonium ; CL:0000020' and 'primary spermatocyte ; CL:0000656'.								biological_process											owl:Class	
GO:0060158	biolink:NamedThing	phospholipase C-activating dopamine receptor signaling pathway	The series of molecular signals generated as a consequence of a dopamine receptor binding to its physiological ligand, where the pathway proceeds with activation of phospholipase C (PLC) and a subsequent release of inositol trisphosphate (IP3) and diacylglycerol (DAG).	tmpzr1t_l9r_go_relaxed.owl	activation of phospholipase C activity by dopamine receptor signaling pathway|activation of phospholipase C activity by dopamine receptor signalling pathway|dopamine receptor, phospholipase C activating pathway													biological_process											owl:Class	
GO:2000246	biolink:NamedThing	positive regulation of FtsZ-dependent cytokinesis	Any process that activates or increases the frequency, rate or extent of Ftsz-dependent cytokinesis.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of prokaryotic fission|positive regulation of prokaryote-type cytokinesis							mah	2010-11-10T02:46:41Z					biological_process											owl:Class	
GO:0006791	biolink:NamedThing	sulfur utilization	A series of processes that forms an integrated mechanism by which a cell or an organism detects the depletion of primary sulfur sources and then activates genes to scavenge the last traces of the primary sulfur source and to transport and metabolize alternate sulfur sources. The utilization process begins when the cell or organism detects sulfur levels, includes the activation of genes whose products detect, transport or metabolize sulfur-containing compounds, and ends when the sulfur is incorporated into the cell or organism's metabolism.	tmpzr1t_l9r_go_relaxed.owl	sulphur utilization													biological_process											owl:Class	
GO:0035941	biolink:NamedThing	androstenedione secretion	The regulated release of androstenedione (androst-4-ene-3,17-dione) into the circulatory system.	tmpzr1t_l9r_go_relaxed.owl	androst-4-ene-3,17-dione secretion							bf	2011-07-25T02:11:47Z					biological_process											owl:Class	
GO:0045508	biolink:NamedThing	interleukin-26 receptor activity	Combining with interleukin-26 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	IL-26R|IL-26 receptor activity													molecular_function											owl:Class	
GO:0045512	biolink:NamedThing	interleukin-26 binding	Binding to interleukin-26.	tmpzr1t_l9r_go_relaxed.owl	IL-26 binding													molecular_function											owl:Class	
GO:1990026	biolink:NamedThing	hippocampal mossy fiber expansion	Synaptic expansion of hippocampal mossy fiber axon that makes contact with the thorny excrescences of hippocampal CA3 pyramidal cell dendrites.	tmpzr1t_l9r_go_relaxed.owl	dentate gyrus granule cell axonal bouton|mossy fiber expansion|dentate gyrus mossy fiber expansion				NIF_Subcellular:nlx_subcell_1005002			pr	2013-02-06T10:31:59Z					cellular_component											owl:Class	
GO:0097457	biolink:NamedThing	hippocampal mossy fiber	Axon of dentate gyrus granule cell projecting to hippocampal area CA3, characterized by expansions (mossy fiber expansions) giving the fibers a mossy appearance. These unmyelinated axons were first described by Ramon y Cajal.	tmpzr1t_l9r_go_relaxed.owl					NIF_Subcellular:nlx_subcell_100312			pr	2012-12-19T16:51:57Z					cellular_component											owl:Class	
GO:1903972	biolink:NamedThing	regulation of cellular response to macrophage colony-stimulating factor stimulus	Any process that modulates the frequency, rate or extent of cellular response to macrophage colony-stimulating factor stimulus.	tmpzr1t_l9r_go_relaxed.owl	regulation of cellular response to macrophage colony-stimulating factor|regulation of cellular response to M-CSF stimulus							nc	2015-03-02T14:50:14Z					biological_process											owl:Class	
GO:0035182	biolink:NamedThing	female germline ring canal outer rim	An electron opaque backbone of the insect ovarian ring canal that is a part of or adjacent to the plasma membrane. The outer rim is established as the cleavage furrow is arrested, and contains F-actin, anillin, glycoproteins and at least one a protein with a high content of phosphorylated tyrosine residues.	tmpzr1t_l9r_go_relaxed.owl	germline ring canal outer rim|nurse cell ring canal outer rim|ovarian ring canal outer rim					See also the fly_anatomy.ontology term 'outer nurse cell ring canal rim ; FBbt:00004882'.								cellular_component											owl:Class	
GO:1900587	biolink:NamedThing	arugosin biosynthetic process	The chemical reactions and pathways resulting in the formation of arugosin.	tmpzr1t_l9r_go_relaxed.owl	arugosin biosynthesis|arugosin formation|arugosin synthesis|arugosin anabolism							di	2012-05-15T06:48:45Z					biological_process											owl:Class	
GO:0031028	biolink:NamedThing	septation initiation signaling	The series of molecular signals, mediated by the small GTPase Ras, that results in the initiation of contraction of the contractile ring, at the beginning of cytokinesis and cell division by septum formation. The pathway coordinates chromosome segregation with mitotic exit and cytokinesis.	tmpzr1t_l9r_go_relaxed.owl	septation initiation signaling cascade|SIN|septation initiation signalling|septation initiation network													biological_process											owl:Class	
GO:1904003	biolink:NamedThing	negative regulation of sebum secreting cell proliferation	Any process that stops, prevents or reduces the frequency, rate or extent of sebum secreting cell proliferation.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of sebocyte proliferation|downregulation of sebocyte proliferation|inhibition of sebocyte proliferation|down-regulation of sebum secreting cell proliferation|downregulation of sebum secreting cell proliferation|inhibition of sebum secreting cell proliferation|down regulation of sebocyte proliferation|down-regulation of sebocyte proliferation|down regulation of sebum secreting cell proliferation							hjd	2015-03-06T16:19:50Z					biological_process											owl:Class	
GO:0097211	biolink:NamedThing	cellular response to gonadotropin-releasing hormone	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gonadotropin-releasing hormone stimulus. Gonadotropin-releasing hormone (GnRH) is a peptide hormone responsible for the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) from the anterior pituitary. GnRH is synthesized and released by the hypothalamus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to GnRH|cellular response to gonadotrophin-releasing hormone							pr	2012-01-09T08:51:23Z					biological_process											owl:Class	
GO:0071002	biolink:NamedThing	U4atac/U6atac snRNP	A ribonucleoprotein complex that contains the extensively base paired small nuclear RNAs U4atac and U6atac, a heptameric ring of Sm proteins associated with U4atac, the Lsm2-8 heptameric ring complex associated with U6atac, as well as several proteins that are unique to the U4atac snRNP or U6atac snRNPs, some of which remain associated with the U4atac/U6atac snRNA both while the U4atac snRNP is free or assembled into a series of spliceosomal complexes.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-07-30T12:00:35Z					cellular_component											owl:Class	
GO:0005690	biolink:NamedThing	U4atac snRNP	A ribonucleoprotein complex that contains small nuclear RNA U4atac, a heptameric ring of Sm proteins, as well as several proteins that are unique to the U4atac snRNP, most of which remain associated with the U4atac snRNA both while the U4atac snRNP is free or assembled into the U4atac/U6atac complex or into a series of spliceosomal complexes.	tmpzr1t_l9r_go_relaxed.owl	snRNP U4atac													cellular_component											owl:Class	
GO:0034107	biolink:NamedThing	negative regulation of erythrocyte clearance	Any process that stops, prevents, or reduces the frequency, rate, or extent of erythrocyte clearance.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of red blood cell clearance|negative regulation of neocytolysis|negative regulation of RBC clearance													biological_process											owl:Class	
GO:0071673	biolink:NamedThing	positive regulation of smooth muscle cell chemotaxis	Any process that activates or increases the frequency, rate, or extent of smooth muscle cell chemotaxis.	tmpzr1t_l9r_go_relaxed.owl	stimulation of smooth muscle cell chemotaxis|upregulation of smooth muscle cell chemotaxis|up regulation of smooth muscle cell chemotaxis|activation of smooth muscle cell chemotaxis|up-regulation of smooth muscle cell chemotaxis							mah	2010-02-16T01:48:14Z					biological_process											owl:Class	
GO:0071670	biolink:NamedThing	smooth muscle cell chemotaxis	The directed movement of a smooth muscle cell in response to an external stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-02-16T01:32:59Z					biological_process											owl:Class	
GO:1900151	biolink:NamedThing	regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	Any process that modulates the frequency, rate or extent of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay.	tmpzr1t_l9r_go_relaxed.owl	regulation of mRNA catabolism, deadenylation-dependent|regulation of nuclear mRNA catabolic process, deadenylation-dependent decay|regulation of mRNA degradation, deadenylation-dependent decay|regulation of mRNA catabolic process, deadenylation-dependent|regulation of mRNA catabolism, deadenylylation-dependent|regulation of deadenylation-dependent mRNA decay|regulation of mRNA breakdown, deadenylation-dependent decay|regulation of mRNA catabolic process, deadenylylation-dependent							bf	2012-03-07T09:14:43Z					biological_process											owl:Class	
GO:0072228	biolink:NamedThing	metanephric prebend segment development	The process whose specific outcome is the progression of the metanephric prebend segment over time, from its formation to the mature structure. The metanephric prebend segment is a part of the metanephric descending thin limb that lies before the bend and exhibits permeabilities characteristic of the ascending limb, especially negligible water permeability.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-03-18T03:37:46Z					biological_process											owl:Class	
GO:0072220	biolink:NamedThing	metanephric descending thin limb development	The process whose specific outcome is the progression of the metanephric descending thin limb over time, from its formation to the mature structure. The metanephric descending thin limb is a part of the metanephric loop of Henle situated just after the proximal straight tubule (S3). It extends to the tip of the metanephric loop of Henle.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-03-18T03:35:05Z					biological_process											owl:Class	
GO:0060171	biolink:NamedThing	stereocilium membrane	The portion of the plasma membrane surrounding a stereocilium.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0016078	biolink:NamedThing	tRNA catabolic process	The chemical reactions and pathways resulting in the breakdown of tRNA, transfer RNA, a class of relatively small RNA molecules responsible for mediating the insertion of amino acids into the sequence of nascent polypeptide chains during protein synthesis.	tmpzr1t_l9r_go_relaxed.owl	tRNA breakdown|tRNA degradation|tRNA catabolism													biological_process											owl:Class	
GO:1903640	biolink:NamedThing	negative regulation of gastrin-induced gastric acid secretion	Any process that stops, prevents or reduces the frequency, rate or extent of gastrin-induced gastric acid secretion.	tmpzr1t_l9r_go_relaxed.owl	inhibition of gastrin-induced gastric acid secretion|down-regulation of gastrin-induced gastric acid secretion|down regulation of gastrin-induced gastric acid secretion|downregulation of gastrin-induced gastric acid secretion							sl	2014-11-20T20:54:28Z					biological_process											owl:Class	
GO:0001698	biolink:NamedThing	gastrin-induced gastric acid secretion	The regulated release of gastric acid induced by the interaction of gastrin with its receptor.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0061084	biolink:NamedThing	negative regulation of protein refolding	Any process that decreases the rate, frequency, or extent of protein refolding. Protein refolding is the process carried out by a cell that restores the biological activity of an unfolded or misfolded protein, using helper proteins such as chaperones.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-04-26T01:11:29Z					biological_process											owl:Class	
GO:0042026	biolink:NamedThing	protein refolding	The process carried out by a cell that restores the biological activity of an unfolded or misfolded protein, using helper proteins such as chaperones.	tmpzr1t_l9r_go_relaxed.owl	heat shock protein activity													biological_process											owl:Class	
GO:0080186	biolink:NamedThing	developmental vegetative growth	The increase in size or mass of non-reproductive plant parts.	tmpzr1t_l9r_go_relaxed.owl								dhl	2011-08-17T03:45:53Z					biological_process											owl:Class	
GO:0061989	biolink:NamedThing	sperm karyosome formation	The chromosome organization process in which meiotic chromosomes in the spem nucleus cluster together to form a compact spherical structure called the karyosome.	tmpzr1t_l9r_go_relaxed.owl								dph	2018-02-15T21:29:47Z					biological_process											owl:Class	
GO:0097087	biolink:NamedThing	interleukin-17A production	The appearance of interleukin-17A due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	tmpzr1t_l9r_go_relaxed.owl	interleukin-17A biosynthetic process|IL-17A production							bc	2011-06-23T11:31:10Z			GO:0150154		biological_process											owl:Class	
GO:0080037	biolink:NamedThing	negative regulation of cytokinin-activated signaling pathway	Any process that stops, prevents, or reduces the frequency, rate or extent of cytokinin signaling.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of cytokinin mediated signalling|negative regulation of cytokinin mediated signaling pathway													biological_process											owl:Class	
GO:1902985	biolink:NamedThing	mitotic pre-replicative complex assembly	Any pre-replicative complex assembly involved in mitotic cell cycle DNA replication.	tmpzr1t_l9r_go_relaxed.owl	nuclear pre-replicative complex assembly involved in mitotic cell cycle|pre-replicative complex assembly involved in mitotic cell cycle DNA replication							jl	2014-05-06T20:33:34Z					biological_process											owl:Class	
GO:0044754	biolink:NamedThing	autolysosome	A type of secondary lysosome in which a primary lysosome has fused with the outer membrane of an autophagosome. It is involved in the second step of autophagy in which it degrades contents with acidic lysosomal hydrolases.	tmpzr1t_l9r_go_relaxed.owl	degrading autophagic vacuole|autophagolysosome|AVd				NIF_Subcellular:sao8444068431			jl	2012-11-27T15:42:12Z					cellular_component											owl:Class	
GO:0060033	biolink:NamedThing	anatomical structure regression	The developmental process in which an anatomical stucture is destroyed as a part of its normal progression.	tmpzr1t_l9r_go_relaxed.owl	histolysis|tissue death													biological_process											owl:Class	
GO:0106186	biolink:NamedThing	cytoplasmic side of plasma membrane, cell tip	The leaflet the plasma membrane at the cell tip that faces the cytoplasm and any proteins embedded or anchored in it or attached to its surface.	tmpzr1t_l9r_go_relaxed.owl								hjd	2019-05-01T17:48:02Z					cellular_component											owl:Class	
GO:0050750	biolink:NamedThing	low-density lipoprotein particle receptor binding	Binding to a low-density lipoprotein receptor.	tmpzr1t_l9r_go_relaxed.owl	low-density lipoprotein receptor binding|LDL receptor binding													molecular_function											owl:Class	
GO:0004430	biolink:NamedThing	1-phosphatidylinositol 4-kinase activity	Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol + ATP = 1-phosphatidyl-1D-myo-inositol 4-phosphate + ADP + 2 H(+).	tmpzr1t_l9r_go_relaxed.owl	PI4K-alpha activity|PI4-kinase activity|PtdIns-4-kinase activity|PI kinase activity|PI4K|PI 4-kinase activity|phosphatidylinositol kinase (phosphorylating) activity|type II phosphatidylinositol kinase activity|phosphatidylinositol kinase activity|phosphatidylinositol 4-kinase activity|ATP:1-phosphatidyl-1D-myo-inositol 4-phosphotransferase activity				EC:2.7.1.67|KEGG_REACTION:R03361|Reactome:R-HSA-1675780|Reactome:R-HSA-1675813|MetaCyc:1-PHOSPHATIDYLINOSITOL-KINASE-RXN|RHEA:19877|Reactome:R-HSA-1675974|Reactome:R-HSA-1676185|Reactome:R-HSA-1675883									molecular_function											owl:Class	
GO:0090369	biolink:NamedThing	ornithine carbamoyltransferase inhibitor activity	Binds to and stops, prevents, or reduces the activity of ornithine carbamoyltransferase.	tmpzr1t_l9r_go_relaxed.owl								tb	2010-07-12T11:19:55Z					molecular_function											owl:Class	
GO:0001984	biolink:NamedThing	artery vasodilation involved in baroreceptor response to increased systemic arterial blood pressure	An increase in the internal diameter of an artery, triggered by vasomotor suppression, during the chemoreceptor response to decreased blood pressure.	tmpzr1t_l9r_go_relaxed.owl	vasodilation of artery involved in baroreceptor response to increased systemic arterial blood pressure													biological_process											owl:Class	
GO:0097536	biolink:NamedThing	thymus epithelium morphogenesis	The process in which the thymus epithelium is generated and organized.	tmpzr1t_l9r_go_relaxed.owl	thymic epithelium morphogenesis							pr	2013-11-28T10:51:03Z					biological_process											owl:Class	
GO:0009693	biolink:NamedThing	ethylene biosynthetic process	The chemical reactions and pathways resulting in the formation of ethylene (C2-H4, ethene), a simple hydrocarbon gas that can function in plants as a growth regulator.	tmpzr1t_l9r_go_relaxed.owl	ethylene anabolism|ethene biosynthesis|ethylene biosynthesis|ethylene biosynthesis from L-methionine|ethylene biosynthetic process from L-methionine|ethylene formation|ethylene synthesis|ethene biosynthesis from L-methionine|ethene biosynthetic process|ethene biosynthetic process from L-methionine				MetaCyc:ETHYL-PWY							GO:0042456		biological_process											owl:Class	
GO:1903915	biolink:NamedThing	positive regulation of fusion of virus membrane with host plasma membrane	Any process that activates or increases the frequency, rate or extent of fusion of virus membrane with host plasma membrane.	tmpzr1t_l9r_go_relaxed.owl	up regulation of viral entry into host cell via membrane fusion with the plasma membrane|activation of viral-cell fusion molecule activity|positive regulation of viral entry into host cell via membrane fusion with the plasma membrane|positive regulation of viral envelope fusion with host plasma membrane|up-regulation of viral envelope fusion with host membrane|up regulation of fusion of virus membrane with host plasma membrane|positive regulation of viral-cell fusion molecule activity|up-regulation of viral entry into host cell via membrane fusion with the plasma membrane|up regulation of viral envelope fusion with host plasma membrane|activation of viral envelope fusion with host cell membrane|up-regulation of viral envelope fusion with host cell membrane|positive regulation of viral envelope fusion with host cell membrane|activation of viral envelope fusion with host plasma membrane|up-regulation of fusion of virus membrane with host plasma membrane|up regulation of viral envelope fusion with host cell membrane|upregulation of viral envelope fusion with host plasma membrane|up-regulation of viral penetration via membrane fusion|activation of viral penetration via membrane fusion|activation of fusion of virus membrane with host plasma membrane|up regulation of viral envelope fusion with host membrane|up-regulation of viral-cell fusion molecule activity|upregulation of viral-cell fusion molecule activity|upregulation of fusion of virus membrane with host plasma membrane|upregulation of viral envelope fusion with host membrane|upregulation of viral entry into host cell via membrane fusion with the plasma membrane|positive regulation of viral envelope fusion with host membrane|up-regulation of viral envelope fusion with host plasma membrane|upregulation of viral penetration via membrane fusion|activation of viral envelope fusion with host membrane|positive regulation of viral penetration via membrane fusion|upregulation of viral envelope fusion with host cell membrane|up regulation of viral-cell fusion molecule activity|activation of viral entry into host cell via membrane fusion with the plasma membrane|up regulation of viral penetration via membrane fusion							als	2015-02-09T11:13:41Z					biological_process											owl:Class	
GO:0035217	biolink:NamedThing	labial disc development	Progression of the labial imaginal disc over time, from its initial formation through to its metamorphosis to form adult structures including parts of the proboscis.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0048053	biolink:NamedThing	R1/R6 development	The process whose specific outcome is the progression of the R1 and R6 pair of photoreceptors in the eye over time, from their formation to the mature structures. R1 and R6 are paired photoreceptors that contribute to the outer rhabdomeres. An example of this process is found in Drosophila melanogaster.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1990793	biolink:NamedThing	substance P secretion, neurotransmission	The controlled release of substance P by a cell, in which the substance P acts as a neurotransmitter.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-07-09T19:43:36Z					biological_process											owl:Class	
GO:0060241	biolink:NamedThing	lysozyme inhibitor activity	Binds to and stops, prevents or reduces the activity of lysozyme.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1904836	biolink:NamedThing	facioacoustic ganglion morphogenesis	The developmental process by which an acoustico-facial VII-VIII ganglion complex is generated and organized.	tmpzr1t_l9r_go_relaxed.owl	acousticofacial ganglion morphogenesis|facio-acoustic ganglion morphogenesis|acoustico-facial VII-VIII ganglion complex morphogenesis|facio-acoustic ganglion complex VII-VIII morphogenesis|facio-acoustic VII-VIII ganglion complex morphogenesis|facio-acoustic ganglion complex morphogenesis							bf	2015-12-01T17:02:06Z					biological_process											owl:Class	
GO:1903375	biolink:NamedThing	facioacoustic ganglion development	The process whose specific outcome is the progression of an acoustico-facial VII-VIII ganglion complex over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl	facio-acoustic VII-VIII ganglion complex development|facio-acoustic ganglion development|acoustico-facial VII-VIII ganglion complex development|facio-acoustic ganglion complex VII-VIII development|acousticofacial ganglion development							bf	2014-08-26T12:40:36Z					biological_process											owl:Class	
GO:0044646	biolink:NamedThing	envenomation resulting in modulation of complement activation in other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant modulation of complement activation in the bitten/stung organism.	tmpzr1t_l9r_go_relaxed.owl	envenomation resulting in regulation of complement activation in other organism							jl	2012-07-11T12:49:28Z					biological_process											owl:Class	
GO:0090543	biolink:NamedThing	Flemming body	A cell part that is the central region of the midbody characterized by a gap in alpha-tubulin staining. It is a dense structure of antiparallel microtubules from the central spindle in the middle of the intercellular bridge.	tmpzr1t_l9r_go_relaxed.owl	Midbody ring							tb	2013-02-14T17:24:43Z					cellular_component											owl:Class	
GO:0030496	biolink:NamedThing	midbody	A thin cytoplasmic bridge formed between daughter cells at the end of cytokinesis. The midbody forms where the contractile ring constricts, and may persist for some time before finally breaking to complete cytokinesis.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Midbody_(cell_biology)									cellular_component											owl:Class	
GO:0099064	biolink:NamedThing	integral component of postsynaptic endosome membrane	The component of the postsynaptic endosome membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0072206	biolink:NamedThing	metanephric juxtaglomerular apparatus development	The process whose specific outcome is the progression of the juxtaglomerular apparatus in the metanephros over time, from its formation to the mature structure. The juxtaglomerular apparatus is an anatomical structure which consists of juxtaglomerular cells, extraglomerular mesangial cells and the macula densa. The juxtaglomerular apparatus lies adjacent to the glomerulus and regulates kidney function by maintaining the blood flow to the kidney and the filtration rate.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-03-18T11:17:47Z					biological_process											owl:Class	
GO:1990956	biolink:NamedThing	fibroblast chemotaxis	The directed movement of a fibroblast guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).	tmpzr1t_l9r_go_relaxed.owl								dph	2016-06-02T19:54:19Z					biological_process											owl:Class	
GO:0021689	biolink:NamedThing	cerebellar molecular layer structural organization	The process that contributes to the act of creating the structural organization of the cerebellar molecular layer. This process pertains to the physical shaping of a rudimentary structure. The molecular layer is the outermost layer of the cerebellar cortex. It contains the parallel fibers of the granule cells, interneurons such as stellate and basket cells, and the dendrites of the underlying Purkinje cells.	tmpzr1t_l9r_go_relaxed.owl	cerebellar molecular layer structural organisation													biological_process											owl:Class	
GO:0032695	biolink:NamedThing	negative regulation of interleukin-12 production	Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-12 production.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of IL-12 production|down regulation of interleukin-12 production|inhibition of interleukin-12 production|negative regulation of interleukin-12 biosynthetic process|negative regulation of CLMF production|negative regulation of NKSF production|downregulation of interleukin-12 production|negative regulation of interleukin-12 secretion|down-regulation of interleukin-12 production											GO:2001183|GO:0045083		biological_process											owl:Class	
GO:0010516	biolink:NamedThing	negative regulation of cellular response to nitrogen starvation	Any process that stops, prevents, or reduces the frequency, rate or extent of a cellular response to nitrogen starvation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0070306	biolink:NamedThing	lens fiber cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a lens fiber cell, any of the elongated, tightly packed cells that make up the bulk of the mature lens in the camera-type eye. The cytoplasm of a lens fiber cell is devoid of most intracellular organelles including the cell nucleus, and contains primarily crystallins, a group of water-soluble proteins expressed in vary large quantities.	tmpzr1t_l9r_go_relaxed.owl	lens fibre cell differentiation													biological_process											owl:Class	
GO:0001899	biolink:NamedThing	negative regulation of cytolysis by symbiont of host cells	Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of cytolysis by that organism of cells in its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	inhibition by symbiont of cytolysis of host cells|down-regulation by symbiont of cytolysis of host cells|down regulation by symbiont of cytolysis of host cells|downregulation by symbiont of cytolysis of host cells|negative regulation by symbiont of cytolysis of host cells													biological_process											owl:Class	
GO:0007540	biolink:NamedThing	sex determination, establishment of X:A ratio	The developmental process in which an organism senses the number of X chromosomes and autosomes in its genomic complement and responds to it.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0007539	biolink:NamedThing	primary sex determination, soma	The transmission of information about sexual status from the initial, general, determination to signals specific to the soma.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0033374	biolink:NamedThing	protein localization to T cell secretory granule	A process in which a protein is transported to, or maintained in, a location within a secretory granule in a T cell.	tmpzr1t_l9r_go_relaxed.owl	protein localisation in T cell secretory granule|protein localization in T lymphocyte secretory granule|protein localization in T cell secretory granule|protein localization in T-lymphocyte secretory granule|protein localization in T-cell secretory granule													biological_process											owl:Class	
GO:0033371	biolink:NamedThing	T cell secretory granule organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a secretory granule in a T cell. A secretory granule is a small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion.	tmpzr1t_l9r_go_relaxed.owl	T cell secretory granule organisation|T-lymphocyte secretory granule maturation|T-cell secretory granule organization|T-lymphocyte secretory granule organization|T lymphocyte secretory granule organization|T cell secretory granule organization and biogenesis													biological_process											owl:Class	
GO:0000738	biolink:NamedThing	DNA catabolic process, exonucleolytic	The chemical reactions and pathways resulting in the breakdown of DNA, involving the hydrolysis of terminal 3',5'-phosphodiester bonds in one or two strands of deoxyribonucleotides.	tmpzr1t_l9r_go_relaxed.owl	DNA degradation, exonucleolytic|exonucleolytic degradation of DNA|DNA breakdown, exonucleolytic													biological_process											owl:Class	
GO:0043415	biolink:NamedThing	positive regulation of skeletal muscle tissue regeneration	Any process that activates or increase the rate of skeletal muscle regeneration.	tmpzr1t_l9r_go_relaxed.owl	activation of skeletal muscle regeneration|up regulation of skeletal muscle regeneration|stimulation of skeletal muscle regeneration|upregulation of skeletal muscle regeneration|up-regulation of skeletal muscle regeneration													biological_process											owl:Class	
GO:0046930	biolink:NamedThing	pore complex	A protein complex providing a discrete opening in a membrane that allows the passage of gases and/or liquids.	tmpzr1t_l9r_go_relaxed.owl	pore|channel-forming toxin activity|pore-forming toxin activity	https://github.com/geneontology/go-ontology/issues/20452												cellular_component											owl:Class	
GO:0099049	biolink:NamedThing	clathrin coat assembly involved in endocytosis	The process that results in the assembly of clathrin triskelia into a clathrin cage during endocytosis. Clathrin is recruited to the plasma membrane via interaction with scaffolding proteins that bridge between clathtin and cell surface receptors. Clathrin coat formation is concomittant with coated pit formation leading to endocytic vesicle formation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0060455	biolink:NamedThing	negative regulation of gastric acid secretion	Any process that decreases the rate frequency or extent of gastric secretion. Gastric secretion is the regulated release of gastric acid (hydrochloric acid) by parietal or oxyntic cells during digestion.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0001696	biolink:NamedThing	gastric acid secretion	The regulated release of gastric acid (hydrochloric acid) by parietal or oxyntic cells during digestion.	tmpzr1t_l9r_go_relaxed.owl	hydrochloric acid secretion													biological_process											owl:Class	
GO:2000292	biolink:NamedThing	regulation of defecation	Any process that modulates the frequency, rate or extent of defecation.	tmpzr1t_l9r_go_relaxed.owl								bf	2010-12-21T09:23:08Z					biological_process											owl:Class	
GO:0038090	biolink:NamedThing	positive regulation of cell migration by VEGF-activated platelet derived growth factor receptor signaling pathway	A series of molecular signals initiated by the binding of a vascular endothelial growth factor (VEGF) to a platelet-derived growth factor receptor (PDGFR) on the surface of a cell, which activates or increases the frequency, rate or extent of the orderly movement of a cell from one site to another.	tmpzr1t_l9r_go_relaxed.owl	VEGF/PDGFR-induced cell migration|positive regulation of cell migration by VEGF-activated platelet derived growth factor receptor signalling pathway|positive regulation of cell migration by VEGF/PDGFR signaling pathway							bf	2012-02-02T03:41:23Z					biological_process											owl:Class	
GO:0017055	biolink:NamedThing	negative regulation of RNA polymerase II transcription preinitiation complex assembly	Any process that stops, prevents, or reduces the frequency, rate or extent of RNA polymerase II transcriptional preinitiation complex assembly.	tmpzr1t_l9r_go_relaxed.owl	inhibition of RNA polymerase II transcriptional preinitiation complex assembly|down regulation of RNA polymerase II transcriptional preinitiation complex assembly|negative regulation of RNA polymerase II transcriptional preinitiation complex assembly|downregulation of RNA polymerase II transcriptional preinitiation complex assembly|down-regulation of RNA polymerase II transcriptional preinitiation complex assembly|negative regulation of RNA polymerase II transcriptional pre-initiation complex biosynthesis|negative regulation of RNA polymerase II transcriptional pre-initiation complex assembly|negative regulation of RNA polymerase II transcriptional preinitiation complex formation													biological_process											owl:Class	
GO:0051123	biolink:NamedThing	RNA polymerase II preinitiation complex assembly	The aggregation, arrangement and bonding together of proteins on an RNA polymerase II promoter DNA to form the transcriptional preinitiation complex (PIC), the formation of which is a prerequisite for transcription by RNA polymerase.	tmpzr1t_l9r_go_relaxed.owl	RNA polymerase II transcriptional preinitiation complex assembly|RNA polymerase II transcriptional preinitiation complex formation|RNA polymerase II transcription PIC formation|RNA polymerase II transcription PIC biosynthesis													biological_process											owl:Class	
GO:0008406	biolink:NamedThing	gonad development	The process whose specific outcome is the progression of the gonad over time, from its formation to the mature structure. The gonad is an animal organ that produces gametes; in some species it also produces hormones.	tmpzr1t_l9r_go_relaxed.owl	gonadogenesis													biological_process											owl:Class	
GO:1990380	biolink:NamedThing	Lys48-specific deubiquitinase activity	Hydrolysis of Lys48-linked ubiquitin unit(s) from a ubiquitinated protein.	tmpzr1t_l9r_go_relaxed.owl	K48-specific deubiquitinase activity|K48-specific deubiquitinating activity				Reactome:R-HSA-5690870			bf	2014-05-15T14:31:07Z					molecular_function											owl:Class	
GO:0046968	biolink:NamedThing	peptide antigen transport	The directed movement of a peptide antigen into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. The peptide antigen is typically, but not always, processed from an endogenous or exogenous protein.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0000916	biolink:NamedThing	actomyosin contractile ring contraction	The process of an actomyosin ring getting smaller in diameter, in the context of cytokinesis that takes place as part of a cell cycle.	tmpzr1t_l9r_go_relaxed.owl	cytokinesis, contractile ring contraction|contractile ring contraction involved in cell cycle cytokinesis|cytokinesis, actomyosin ring contraction|actomyosin contractile ring constriction	https://github.com/geneontology/go-ontology/issues/21855												biological_process											owl:Class	
GO:0016191	biolink:NamedThing	synaptic vesicle uncoating	The removal of the protein coat on a synaptic vesicle following the pinching step at the end of budding from the presynaptic membrane.	tmpzr1t_l9r_go_relaxed.owl	synaptic vesicle coat depolymerization|synaptic vesicle coat protein depolymerization													biological_process											owl:Class	
GO:0021714	biolink:NamedThing	inferior olivary nucleus morphogenesis	The process in which the anatomical structure of the inferior olivary nucleus is generated and organized. The inferior olivary nucleus is a capsule-shaped structure in the ventral medulla located just lateral and dorsal to the medullary pyramids. Neurons in the inferior olivary nucleus are the source of climbing fiber input to the cerebellar cortex; these neurons have been implicated in various functions, such as learning and timing of movements.	tmpzr1t_l9r_go_relaxed.owl	inferior olive morphogenesis													biological_process											owl:Class	
GO:0010215	biolink:NamedThing	cellulose microfibril organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cellulose microfibril, any of the cellulose structures laid down in orthogonal layers in a plant cell wall.	tmpzr1t_l9r_go_relaxed.owl	cellulose microfibril organisation													biological_process											owl:Class	
GO:0070977	biolink:NamedThing	bone maturation	A developmental process, independent of morphogenetic (shape) change, that is required for bone to attain its fully functional state.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-10-05T04:35:31Z					biological_process											owl:Class	
GO:0090172	biolink:NamedThing	microtubule cytoskeleton organization involved in homologous chromosome segregation	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins that contributes to chromosomal pairing and precedes synapsis.	tmpzr1t_l9r_go_relaxed.owl	microtubule organization involved in chromosome pairing|microtubule cytoskeleton organisation involved in homologous chromosome segregation							tb	2009-12-11T11:07:42Z					biological_process											owl:Class	
GO:0045143	biolink:NamedThing	homologous chromosome segregation	The cell cycle process in which replicated homologous chromosomes are organized and then physically separated and apportioned to two sets during the first division of the meiotic cell cycle. Each replicated chromosome, composed of two sister chromatids, aligns at the cell equator, paired with its homologous partner; this pairing off, referred to as synapsis, permits genetic recombination. One homolog (both sister chromatids) of each morphologic type goes into each of the resulting chromosome sets.	tmpzr1t_l9r_go_relaxed.owl	meiosis I, chromosome segregation											GO:0007061		biological_process											owl:Class	
GO:0006655	biolink:NamedThing	phosphatidylglycerol biosynthetic process	The chemical reactions and pathways resulting in the formation of phosphatidylglycerols, any of a class of phospholipids in which the phosphatidyl group is esterified to the hydroxyl group of glycerol.	tmpzr1t_l9r_go_relaxed.owl	phosphatidylglycerol anabolism|phosphatidylglycerol biosynthesis|phosphatidylglycerol synthesis|phosphatidylglycerol formation													biological_process											owl:Class	
GO:2001099	biolink:NamedThing	maltotetraose transport	The directed movement of a maltotetraoseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl								jl	2011-09-21T02:15:03Z					biological_process											owl:Class	
GO:0007458	biolink:NamedThing	progression of morphogenetic furrow involved in compound eye morphogenesis	The morphogenetic furrow is a dorsoventral indentation which sweeps anteriorly across the eye disc. Ommatidia begin to form along the furrow, resulting in a graded series of ommatidial development across the anterior/posterior axis of the disc.	tmpzr1t_l9r_go_relaxed.owl	progression of morphogenetic furrow during compound eye morphogenesis													biological_process											owl:Class	
GO:0048755	biolink:NamedThing	branching morphogenesis of a nerve	The process in which the anatomical structures of branches in a nerve are generated and organized. This term refers to an anatomical structure (nerve) not a cell (neuron).	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0021807	biolink:NamedThing	motogenic signaling initiating cell movement in cerebral cortex	The interaction of soluble factors and receptors that result in the movement of cells in the primitive cerebral cortex.	tmpzr1t_l9r_go_relaxed.owl	motogenic signalling initiating cell movement in the cerebral cortex													biological_process											owl:Class	
GO:0021806	biolink:NamedThing	initiation of movement involved in cerebral cortex radial glia guided migration	The initial stages of cell motility involved in the glial-mediated movement of cells in the developing cerebral cortex.	tmpzr1t_l9r_go_relaxed.owl	initiation of movement involved in cerebral cortex glial-mediated radial migration													biological_process											owl:Class	
GO:2000805	biolink:NamedThing	negative regulation of termination of RNA polymerase II transcription, poly(A)-coupled	Any process that stops, prevents or reduces the frequency, rate or extent of termination of RNA polymerase II transcription, poly(A)-coupled.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of transcription termination from Pol II promoter, RNA polymerase(A) coupled|negative regulation of termination of RNA polymerase II transcription, polyadenylation-coupled|negative regulation of transcription termination from Pol II promoter, poly(A) coupled							pr	2011-07-04T08:41:34Z					biological_process											owl:Class	
GO:0030846	biolink:NamedThing	termination of RNA polymerase II transcription, poly(A)-coupled	The process in which transcription of polyadenylated RNA polymerase II transcripts is terminated; cleavage and polyadenylylation of the mRNA 3' end is coupled to transcription termination.	tmpzr1t_l9r_go_relaxed.owl	termination of RNA polymerase II transcription, polyadenylation-coupled|transcription termination from Pol II promoter, poly(A) coupled|transcription termination from Pol II promoter, RNA polymerase(A) coupled													biological_process											owl:Class	
GO:0060483	biolink:NamedThing	lobar bronchus mesenchyme development	The biological process whose specific outcome is the progression of a lobar bronchus mesenchyme from an initial condition to its mature state. This process begins with the formation of the lobar bronchus mesenchyme and ends with the mature structure. The lobar bronchus mesenchyme is the mass of tissue composed of mesenchymal cells in the lobar bronchus.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0060482	biolink:NamedThing	lobar bronchus development	The biological process whose specific outcome is the progression of a lobar bronchus from an initial condition to its mature state. This process begins with the formation of the lobar bronchus and ends with the mature structure. The lobar bronchus is the major airway within the respiratory tree that starts by division of the principal bronchi on both sides and ends at the point of its own subdivision into tertiary or segmental bronchi.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0050852	biolink:NamedThing	T cell receptor signaling pathway	A series of molecular signals initiated by the cross-linking of an antigen receptor on a T cell.	tmpzr1t_l9r_go_relaxed.owl	TCR signaling pathway|T-lymphocyte receptor signalling pathway|T-cell receptor signalling pathway|T lymphocyte receptor signaling pathway|T lymphocyte receptor signalling pathway|T-cell receptor signaling pathway|T-lymphocyte receptor signaling pathway													biological_process											owl:Class	
GO:0098585	biolink:NamedThing	host cell synaptic vesicle membrane	The lipid bilayer surrounding a host synaptic vesicle.	tmpzr1t_l9r_go_relaxed.owl								dos	2014-01-24T13:15:14Z					cellular_component											owl:Class	
GO:0098584	biolink:NamedThing	host cell synaptic vesicle	A secretory organelle of a host cell, some 50 nm in diameter, of presynaptic nerve terminals; accumulates in high concentrations of neurotransmitters and secretes these into the synaptic cleft by fusion with the 'active zone' of the presynaptic plasma membrane.	tmpzr1t_l9r_go_relaxed.owl								dos	2014-01-24T13:14:13Z					cellular_component											owl:Class	
GO:0002536	biolink:NamedThing	respiratory burst involved in inflammatory response	A phase of elevated metabolic activity, during which oxygen consumption increases following a stimulus as part of an inflammatory response; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals, resulting in an increase in their intracellular or extracellular levels.	tmpzr1t_l9r_go_relaxed.owl	respiratory burst involved in acute inflammatory response|oxidative burst during acute inflammatory response|production of reactive oxygen species during acute inflammatory response													biological_process											owl:Class	
GO:0030934	biolink:NamedThing	anchoring collagen complex	Any collagen complex which links one collagen assembly, such as a collagen fibril or sheet, to other structures.	tmpzr1t_l9r_go_relaxed.owl	connecting collagen|linking collagen													cellular_component											owl:Class	
GO:0005937	biolink:NamedThing	mating projection	The projection formed by unicellular fungi in response to mating pheromone.	tmpzr1t_l9r_go_relaxed.owl	conjugation tube|shmoo													cellular_component											owl:Class	
GO:0035676	biolink:NamedThing	anterior lateral line neuromast hair cell development	The process whose specific outcome is the progression of an anterior lateral line neuromast hair cell over time, from its formation to the mature structure. A neuromast hair cell is a hair cell that acts as a sensory receptor of the neuromast; it is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. Cell development does not include the steps involved in committing a cell to a specific fate.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-02-14T11:03:57Z					biological_process											owl:Class	
GO:0003269	biolink:NamedThing	BMP signaling pathway involved in regulation of secondary heart field cardioblast proliferation	A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, which contributes to the modulation of the frequency, rate or extent of cardioblast proliferation in the secondary heart field. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.	tmpzr1t_l9r_go_relaxed.owl	BMP signaling pathway involved in regulation of second heart field cardioblast proliferation|BMP signalling pathway involved in regulation of secondary heart field cardioblast proliferation							dph	2009-10-15T02:45:28Z					biological_process											owl:Class	
GO:2001034	biolink:NamedThing	positive regulation of double-strand break repair via nonhomologous end joining	Any process that activates or increases the frequency, rate or extent of double-strand break repair via nonhomologous end joining.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of NHEJ							yaf	2011-08-24T09:25:51Z					biological_process											owl:Class	
GO:0075265	biolink:NamedThing	positive regulation of oogonium development	Any process that activates, maintains or increases the frequency, rate or extent of oogonium development, a process that leads to the formation of a female gametangium of oomycetes, containing one or more gametes.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0050657	biolink:NamedThing	nucleic acid transport	The directed movement of nucleic acids, single or double-stranded polynucleotides involved in the storage, transmission and transfer of genetic information, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0006817	biolink:NamedThing	phosphate ion transport	The directed movement of phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	phosphate transport													biological_process											owl:Class	
GO:0090299	biolink:NamedThing	regulation of neural crest formation	Any process that modulates the rate, frequency, or extent of neural crest formation. Neural crest formation is the formation of the specialized region of ectoderm between the neural ectoderm (neural plate) and non-neural ectoderm. The neural crest gives rise to the neural crest cells that migrate away from this region as neural tube formation proceeds.	tmpzr1t_l9r_go_relaxed.owl								tb	2010-03-12T04:08:26Z					biological_process											owl:Class	
GO:0010271	biolink:NamedThing	regulation of chlorophyll catabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of chlorophyll.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0034992	biolink:NamedThing	microtubule organizing center attachment site	A region of the nuclear envelope to which a microtubule organizing center (MTOC) attaches; protein complexes embedded in the nuclear envelope mediate direct or indirect linkages between the microtubule cytoskeleton and the nuclear envelope.	tmpzr1t_l9r_go_relaxed.owl	MTOC attachment site|MAS|microtubule organising centre attachment site					Note that this term should not be confused with the cellular component term 'perinuclear region ; GO:0048471'.								cellular_component											owl:Class	
GO:0046548	biolink:NamedThing	retinal rod cell development	Development of a rod cell, one of the sensory cells in the eye that reacts to the presence of light. Rod cells contain the photopigment rhodopsin or porphyropsin and are responsible for vision in dim light.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0060221	biolink:NamedThing	retinal rod cell differentiation	The process in which a relatively unspecialized cell acquires the specialized features of a retinal rod cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0007465	biolink:NamedThing	R7 cell fate commitment	The process in which the R7 photoreceptor commits to its cell fate. The R7 receptor contributes the central part of the rhabdomere in the apical parts of the ommatidium.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0000718	biolink:NamedThing	nucleotide-excision repair, DNA damage removal	The removal of the oligonucleotide that contains the DNA damage. The oligonucleotide is formed by dual incisions that flank the site of DNA damage.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1902455	biolink:NamedThing	negative regulation of stem cell population maintenance	Any process that stops, prevents or reduces the frequency, rate or extent of stem cell population maintenance.	tmpzr1t_l9r_go_relaxed.owl	downregulation of maintenance of pluripotency|down-regulation of stem cell maintenance|down regulation of maintenance of pluripotency|inhibition of stem cell maintenance|downregulation of stem cell maintenance|down regulation of stem cell maintenance|negative regulation of maintenance of pluripotency|inhibition of maintenance of pluripotency|down-regulation of maintenance of pluripotency							cjm	2013-10-16T22:19:17Z					biological_process											owl:Class	
GO:0042014	biolink:NamedThing	interleukin-19 receptor activity	Combining with interleukin-19 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	IL-19 receptor activity|IL-19R													molecular_function											owl:Class	
GO:0042013	biolink:NamedThing	interleukin-19 binding	Binding to interleukin-19.	tmpzr1t_l9r_go_relaxed.owl	IL-19 binding													molecular_function											owl:Class	
GO:0033101	biolink:NamedThing	cellular bud membrane	The portion of the plasma membrane surrounding a cellular bud.	tmpzr1t_l9r_go_relaxed.owl	cellular bud plasma membrane													cellular_component											owl:Class	
GO:0007443	biolink:NamedThing	Malpighian tubule morphogenesis	The process in which the anatomical structures of the Malpighian tubule are generated and organized. This process takes place entirely during the embryonic phase. A Malpighian tubule is a fine, thin-walled excretory tubule in insects which leads into the posterior part of the gut.	tmpzr1t_l9r_go_relaxed.owl						See also the fly_anatomy.ontology term 'Malpighian tubule ; FBbt:00005786'.								biological_process											owl:Class	
GO:0033563	biolink:NamedThing	dorsal/ventral axon guidance	The process in which the migration of an axon growth cone is directed to a specific target site along the dorsal-ventral body axis in response to a combination of attractive and repulsive cues. The dorsal/ventral axis is defined by a line that runs orthogonal to both the anterior/posterior and left/right axes. The dorsal end is defined by the upper or back side of an organism. The ventral end is defined by the lower or front side of an organism.	tmpzr1t_l9r_go_relaxed.owl	dorsal-ventral axon guidance|dorsal/ventral axon pathfinding|dorsoventral axon guidance													biological_process											owl:Class	
GO:0030085	biolink:NamedThing	PSII associated light-harvesting complex II, peripheral complex, LHCIIb subcomplex	A pigment protein complex that forms part of the photosystem II associated light-harvesting complex II; contains two proteins (usually about 28 and 27 kDa), and may contain a third; peripherally located relative to other LHC polypeptides.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0009656	biolink:NamedThing	PSII associated light-harvesting complex II, peripheral complex	Pigment-protein complex primarily associated to PSII in plants, green algae and cyanobacteria. Involved in state transitions that cause migration to PSI under certain environmental conditions such as high light.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0008384	biolink:NamedThing	IkappaB kinase activity	Catalysis of the reaction: ATP + IkappaB protein = ADP + IkappaB phosphoprotein.	tmpzr1t_l9r_go_relaxed.owl	IKBKA|inhibitor of NFkappaB kinase activity|TBK1|inhibitor of NF-kappaB kinase activity|IKBKB|STK12|IKK-1|CHUK|TANK-binding kinase 1 activity|IKK-2|ATP:IkappaB protein phosphotransferase activity|IKK				Reactome:R-HSA-5684275|Reactome:R-HSA-5684267|RHEA:19073|MetaCyc:2.7.11.10-RXN|EC:2.7.11.10	Note that phosphorylation of IkappaB targets it for proteasomal degradation and allows the nuclear translocation of kB.								molecular_function											owl:Class	
GO:0007252	biolink:NamedThing	I-kappaB phosphorylation	The process of introducing a phosphate group into an inhibitor of kappa B (I-kappaB) protein. Phosphorylation of I-kappaB targets I-kappaB for ubiquitination and proteasomal degradation, thus releasing bound NF-kappaB dimers, which can translocate to the nucleus to bind DNA and regulate transcription.	tmpzr1t_l9r_go_relaxed.owl	IkappaB phosphorylation|inhibitor of NF-kappaB phosphorylation|IKB phosphorylation|inhibitor of kappaB phosphorylation													biological_process											owl:Class	
GO:0001852	biolink:NamedThing	complement component iC3b binding	Binding to a iC3b product of the complement cascade.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0061153	biolink:NamedThing	trachea gland development	The progression of a trachea gland over time, from its formation to the mature structure. Trachea glands are found under the mucus of the trachea and secrete mucus, and agents that help protect the lung from injury and infection.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-06-07T10:10:51Z					biological_process											owl:Class	
GO:0120074	biolink:NamedThing	regulation of endocardial cushion cell differentiation	Any process that modulates the frequency, rate or extent of cell differentiation, the process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of an endocardial cushion cell.	tmpzr1t_l9r_go_relaxed.owl								krc	2017-06-26T23:32:00Z					biological_process											owl:Class	
GO:0014902	biolink:NamedThing	myotube differentiation	The process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotube differentiation starts with myoblast fusion and the appearance of specific cell markers (this is the cell development step). Then individual myotubes can fuse to form bigger myotubes and start to contract. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1901439	biolink:NamedThing	positive regulation of toluene metabolic process	Any process that activates or increases the frequency, rate or extent of toluene metabolic process.	tmpzr1t_l9r_go_relaxed.owl	activation of methylbenzene metabolic process|positive regulation of toluene metabolism|activation of toluene metabolic process|up regulation of toluene metabolism|up-regulation of toluene metabolism|up regulation of toluene metabolic process|activation of toluene metabolism|up-regulation of toluene metabolic process|upregulation of toluene metabolism|positive regulation of methylbenzene metabolic process|upregulation of methylbenzene metabolism|positive regulation of methylbenzene metabolism|up regulation of methylbenzene metabolism|up-regulation of methylbenzene metabolism|upregulation of toluene metabolic process|up regulation of methylbenzene metabolic process|up-regulation of methylbenzene metabolic process|activation of methylbenzene metabolism|upregulation of methylbenzene metabolic process							tt	2012-10-01T21:19:08Z					biological_process											owl:Class	
GO:0120105	biolink:NamedThing	mitotic actomyosin contractile ring, intermediate layer	The region of the mitotic actomyosin ring in between the proximal layer and the actin filament layer. This region contains the accessory protein network, some actin filaments and connections between the proximal layer and the actin filament layer.	tmpzr1t_l9r_go_relaxed.owl	actomyosin contractile ring, intermediate layer							krc	2017-10-11T22:54:40Z					cellular_component											owl:Class	
GO:0015245	biolink:NamedThing	fatty acid transmembrane transporter activity	Enables the transfer of fatty acids from one side of a membrane to the other. Fatty acids are aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis.	tmpzr1t_l9r_go_relaxed.owl	peroxisomal fatty acyl transporter|fatty acid transporter activity|fatty acyl transporter activity|fatty-acyl group transporter activity				Reactome:R-HSA-879585|Reactome:R-HSA-5627891							GO:0015246		molecular_function											owl:Class	
GO:0015908	biolink:NamedThing	fatty acid transport	The directed movement of fatty acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Fatty acids are aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0022000	biolink:NamedThing	forebrain induction by the anterior neural ridge	The close range interaction of the anterior neural ridge to the caudal region of the neural plate that specifies the forebrain fate.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0061927	biolink:NamedThing	TOC-TIC supercomplex I	The protein transport macromolecular complex of the chloroplast membrane that interacts with the precursor proteins and contains components of both the outer membrane and inner membrane complexes containing at least Toc75, Toc159, Toc34 and Tic110.	tmpzr1t_l9r_go_relaxed.owl								dph	2017-08-28T13:18:20Z					cellular_component											owl:Class	
GO:1904448	biolink:NamedThing	regulation of aspartate secretion	Any process that modulates the frequency, rate or extent of aspartate secretion.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-07-07T20:56:57Z					biological_process											owl:Class	
GO:0089700	biolink:NamedThing	protein kinase D signaling	A series of reactions, mediated by the intracellular serine/threonine kinase protein kinase D, which occurs as a result of a single trigger reaction or compound.	tmpzr1t_l9r_go_relaxed.owl	protein kinase D signalling cascade|PKD signaling cascade|PKD signal transduction|protein kinase D signal transduction|protein kinase D signaling cascade													biological_process											owl:Class	
GO:0006703	biolink:NamedThing	estrogen biosynthetic process	The chemical reactions and pathways resulting in the formation of estrogens, C18 steroid hormones that can stimulate the development of female sexual characteristics. Also found in plants.	tmpzr1t_l9r_go_relaxed.owl	estrogen anabolism|oestrogen biosynthetic process|estrogen formation|oestrogen biosynthesis|estrogen biosynthesis|estrogen synthesis													biological_process											owl:Class	
GO:0035436	biolink:NamedThing	triose phosphate transmembrane transport	The process in which triose phosphate (glyceraldehyde 3-phosphate) is transported across a membrane. Glyceraldehyde 3-phosphate is any organic three carbon compound phosphate ester.	tmpzr1t_l9r_go_relaxed.owl	triose phosphate membrane transport					Note that this term is not intended for use in annotating lateral movement within membranes.		bf	2010-04-08T02:54:07Z					biological_process											owl:Class	
GO:0019080	biolink:NamedThing	viral gene expression	A process by which a viral gene is converted into a mature gene product or products (proteins or RNA). This includes viral transcription, processing to produce a mature RNA product, and viral translation.	tmpzr1t_l9r_go_relaxed.owl	viral genome expression													biological_process											owl:Class	
GO:0045270	biolink:NamedThing	plasma membrane proton-transporting ATP synthase, central stalk	One of two stalks that connect the catalytic core of the hydrogen-transporting ATP synthase to the plasma membrane-associated Fo proteins; rotates within the catalytic core during catalysis. Examples of this component are found in Bacterial species.	tmpzr1t_l9r_go_relaxed.owl	proton-transporting ATP synthase, central stalk|hydrogen-transporting ATP synthase, central stalk													cellular_component											owl:Class	
GO:0045262	biolink:NamedThing	plasma membrane proton-transporting ATP synthase complex, catalytic core F(1)	The catalytic sector of the plasma membrane hydrogen-transporting ATP synthase; it comprises the catalytic core and central stalk, and is peripherally associated with the plasma membrane when the entire ATP synthase is assembled. Examples of this component are found in Bacterial species.	tmpzr1t_l9r_go_relaxed.owl	hydrogen-transporting ATP synthase, F1 sector|proton-transporting ATP synthase complex, catalytic core F(1)					See also the cellular component term 'plasma membrane ; GO:0005886'.								cellular_component											owl:Class	
GO:0009273	biolink:NamedThing	peptidoglycan-based cell wall biogenesis	The chemical reactions and pathways resulting in the formation of the peptidoglycan-based cell wall. An example of this process is found in Escherichia coli.	tmpzr1t_l9r_go_relaxed.owl	cell wall formation|cell wall assembly|cell wall anabolism|cell wall synthesis|cell wall biosynthetic process|cell envelope biosynthetic process|cell envelope biosynthesis													biological_process											owl:Class	
GO:0038178	biolink:NamedThing	complement component C5a signaling pathway	A series of molecular signals generated as a consequence of a the C5a component of the complement pathway binding to a complement receptor, and ending with regulation of a downstream cellular process. C5a is a peptide derived from the C5 complement factor.	tmpzr1t_l9r_go_relaxed.owl	complement component C5a-induced signaling pathway							bf	2012-09-21T10:55:00Z					biological_process											owl:Class	
GO:0110160	biolink:NamedThing	negative regulation of mitotic spindle formation (spindle phase one)	Any process that stops, prevents or reduces the frequency, rate or extent of the cell cycle process in which the distance is lengthened between poles of the mitotic spindle during mitotic prophase (spindle phase one).	tmpzr1t_l9r_go_relaxed.owl								kmv	2019-08-12T15:18:32Z					biological_process											owl:Class	
GO:1900670	biolink:NamedThing	regulation of F-9775A biosynthetic process	Any process that modulates the frequency, rate or extent of F-9775A biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of F-9775A anabolism|regulation of F-9775A biosynthesis|regulation of F-9775A formation|regulation of F-9775A synthesis							di	2012-05-22T04:24:09Z					biological_process											owl:Class	
GO:1900611	biolink:NamedThing	F-9775A biosynthetic process	The chemical reactions and pathways resulting in the formation of F-9775A.	tmpzr1t_l9r_go_relaxed.owl	F-9775A synthesis|F-9775A formation|F-9775A biosynthesis|F-9775A anabolism							di	2012-05-15T07:02:56Z					biological_process											owl:Class	
GO:0106104	biolink:NamedThing	regulation of glutamate receptor clustering	Any process that modulates the frequency, rate or extent of glutamate receptor clustering.	tmpzr1t_l9r_go_relaxed.owl								hjd	2018-03-06T15:54:33Z					biological_process											owl:Class	
GO:0097688	biolink:NamedThing	glutamate receptor clustering	The neurotransmitter-gated ion channel clustering process in which glutamate receptors are localized to distinct domains in the cell membrane.	tmpzr1t_l9r_go_relaxed.owl	glutamatergic receptor clustering							pr	2015-02-11T11:49:13Z					biological_process											owl:Class	
GO:0009524	biolink:NamedThing	phragmoplast	Fibrous structure (light microscope view) that arises between the daughter nuclei at telophase and within which the initial partition (cell plate), dividing the mother cell in two (cytokinesis), is formed. Appears at first as a spindle connected to the two nuclei, but later spreads laterally in the form of a ring. Consists of microtubules.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Phragmoplast									cellular_component											owl:Class	
GO:1990916	biolink:NamedThing	Isp3 layer of spore wall	The outermost layers of the spore wall, as described in Schizosaccharomyces pombe.	tmpzr1t_l9r_go_relaxed.owl								al	2015-12-09T19:07:23Z					cellular_component											owl:Class	
GO:0002115	biolink:NamedThing	store-operated calcium entry	A calcium ion entry mechanism in the plasma membrane activated by the depletion of calcium ion from the internal calcium ion store in the endoplasmic reticulum.	tmpzr1t_l9r_go_relaxed.owl	SOCE|store-operated calcium import|capacitative calcium entry|calcium ion import					SOCE is initiated by response to stiumlation of membrane receptors leading to the hydrolysis ofphosphatidylinositol bisphosphate (PIP2), inositol 1,4,5-trisphosphate (IP3) generation, and IP3-mediated calcium ion release from the endoplasmic reticulum.								biological_process											owl:Class	
GO:0099699	biolink:NamedThing	integral component of synaptic membrane	The component of the synaptic membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.	tmpzr1t_l9r_go_relaxed.owl								dos	2017-05-25T17:22:18Z					cellular_component											owl:Class	
GO:0000082	biolink:NamedThing	G1/S transition of mitotic cell cycle	The mitotic cell cycle transition by which a cell in G1 commits to S phase. The process begins with the build up of G1 cyclin-dependent kinase (G1 CDK), resulting in the activation of transcription of G1 cyclins. The process ends with the positive feedback of the G1 cyclins on the G1 CDK which commits the cell to S phase, in which DNA replication is initiated.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0070427	biolink:NamedThing	nucleotide-binding oligomerization domain containing 1 signaling pathway	Any series of molecular signals generated as a consequence of binding to nucleotide-binding oligomerization domain containing 1 (NOD1).	tmpzr1t_l9r_go_relaxed.owl	nucleotide-binding oligomerization domain containing 1 signalling pathway|NOD1 signaling pathway													biological_process											owl:Class	
GO:1903871	biolink:NamedThing	DNA recombinase mediator complex assembly	The aggregation, arrangement and bonding together of a set of components to form a DNA recombinase mediator complex.	tmpzr1t_l9r_go_relaxed.owl	DNA recombinase mediator complex formation							rb	2015-02-05T23:05:10Z					biological_process											owl:Class	
GO:0034744	biolink:NamedThing	APC-IQGAP1-Cdc42 complex	A protein complex that contains the tumor suppressor protein adenomatous polyposis coli (APC), the small GTPase Cdc42, and the Rac1 and Cdc42 effector IQGAP1; may play a role in cytoskeleton organization and cell migration.	tmpzr1t_l9r_go_relaxed.owl						Note that the gene/protein name 'APC' should not be confused with the abbreviation for 'anaphase promoting complex'.								cellular_component											owl:Class	
GO:1905000	biolink:NamedThing	regulation of membrane repolarization during atrial cardiac muscle cell action potential	Any process that modulates the frequency, rate or extent of membrane repolarization during atrial cardiac muscle cell action potential.	tmpzr1t_l9r_go_relaxed.owl	regulation of atrial repolarization|regulation of electrocardiogram QRS complex							rph	2016-03-01T13:28:05Z					biological_process											owl:Class	
GO:0002819	biolink:NamedThing	regulation of adaptive immune response	Any process that modulates the frequency, rate, or extent of an adaptive immune response.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0061068	biolink:NamedThing	urethra development	The progression of the urethra over time from its initial formation to the mature structure. The urethra is a renal system organ that carries urine from the bladder to outside the body.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-03-12T08:24:52Z					biological_process											owl:Class	
GO:0030690	biolink:NamedThing	Noc1p-Noc2p complex	A heterodimer associated with 90S and 66S preribosomes. Predominantly, but not exclusively, nucleolar; involved in ribosomal large subunit biogenesis.	tmpzr1t_l9r_go_relaxed.owl						Noc complexes exhibit a dynamic intranuclear location; consider also annotating to 'nucleolus ; GO:0005730' and/or 'nucleoplasm ; GO:0005654'. Note that the term name uses Saccharomyces gene product names because no other names have yet arisen for this complex; the term nevertheless can be used for analogous complexes in other eukaryotes, and the name can be changed if better wording is found.								cellular_component											owl:Class	
GO:0043009	biolink:NamedThing	chordate embryonic development	The process whose specific outcome is the progression of the embryo over time, from zygote formation through a stage including a notochord and neural tube until birth or egg hatching.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0120276	biolink:NamedThing	regulation of cerebral blood circulation	Any process that modulates the frequency, rate or extent of cerebral blood circulation.	tmpzr1t_l9r_go_relaxed.owl	regulation of cerebrum blood circulation|regulation of telencephalon blood circulation	https://github.com/geneontology/go-ontology/issues/20107						krc	2020-10-21T06:52:22Z					biological_process											owl:Class	
GO:0120275	biolink:NamedThing	cerebral blood circulation	The flow of blood through the network of arteries and veins supplying the cerebrum, enabling the transport of nutrients to the tissues and the removal of waste products.	tmpzr1t_l9r_go_relaxed.owl	telencephelon blood circulation|cerebrum blood circulation	https://github.com/geneontology/go-ontology/issues/20107						krc	2020-10-20T19:13:51Z					biological_process											owl:Class	
GO:0097577	biolink:NamedThing	sequestering of iron ion	The process of binding or confining iron ions such that they are separated from other components of a biological system.	tmpzr1t_l9r_go_relaxed.owl	sequestration of iron ion|storage of iron ion|iron ion storage|iron ion sequestering|iron ion sequestration|retention of iron ion|iron ion retention							pr	2014-02-28T11:10:53Z					biological_process											owl:Class	
GO:1905824	biolink:NamedThing	positive regulation of mitotic sister chromatid arm separation	Any process that activates or increases the frequency, rate or extent of mitotic sister chromatid arm separation.	tmpzr1t_l9r_go_relaxed.owl	activation of mitotic sister chromatid arm separation|up-regulation of mitotic sister chromatid arm separation|upregulation of mitotic sister chromatid arm separation|up regulation of mitotic sister chromatid arm separation							als	2017-01-16T13:36:47Z					biological_process											owl:Class	
GO:0034314	biolink:NamedThing	Arp2/3 complex-mediated actin nucleation	The actin nucleation process in which actin monomers combine to form a new branch on the side of an existing actin filament; mediated by the Arp2/3 protein complex and its interaction with other proteins.	tmpzr1t_l9r_go_relaxed.owl	branched actin filament nucleation|actin filament branch nucleation													biological_process											owl:Class	
GO:0010548	biolink:NamedThing	regulation of thylakoid membrane disassembly	Any process that modulates the frequency, rate or extent of thylakoid membrane disassembly.	tmpzr1t_l9r_go_relaxed.owl	regulation of thylakoid membrane degradation													biological_process											owl:Class	
GO:2000472	biolink:NamedThing	negative regulation of hematopoietic stem cell migration	Any process that stops, prevents or reduces the frequency, rate or extent of hematopoietic stem cell migration.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of hemopoietic stem cell migration							bf	2011-03-09T09:34:54Z					biological_process											owl:Class	
GO:0035701	biolink:NamedThing	hematopoietic stem cell migration	The orderly movement of a hematopoietic stem cell from one site to another. A hematopoietic stem cell is a cell from which all cells of the lymphoid and myeloid lineages develop, including blood cells and cells of the immune system.	tmpzr1t_l9r_go_relaxed.owl	hemopoietic stem cell migration							bf	2011-02-28T03:20:36Z					biological_process											owl:Class	
GO:0002030	biolink:NamedThing	inhibitory G protein-coupled receptor phosphorylation	The process that inhibits the signaling function of a G protein-coupled receptor by addition of a phosphate group to its third intracellular loop consensus site.	tmpzr1t_l9r_go_relaxed.owl	inhibitory G-protein coupled receptor phosphorylation													biological_process											owl:Class	
GO:0003182	biolink:NamedThing	coronary sinus valve morphogenesis	The process in which the structure of the coronary sinus valve is generated and organized.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-10-08T11:33:31Z					biological_process											owl:Class	
GO:0003178	biolink:NamedThing	coronary sinus valve development	The progression of the valve of the coronary sinus over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-10-08T11:21:43Z					biological_process											owl:Class	
GO:1901881	biolink:NamedThing	positive regulation of protein depolymerization	Any process that activates or increases the frequency, rate or extent of protein depolymerization.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of protein polymer catabolism|positive regulation of protein polymer catabolic process|up-regulation of protein polymer breakdown|upregulation of protein polymer catabolism|up-regulation of protein polymer degradation|activation of protein polymer breakdown|activation of protein polymer catabolism|activation of protein polymer degradation|up regulation of protein polymer catabolism|upregulation of protein depolymerization|upregulation of protein polymer degradation|upregulation of protein polymer breakdown|positive regulation of protein polymer breakdown|up regulation of protein polymer breakdown|upregulation of protein polymer catabolic process|up-regulation of protein polymer catabolic process|activation of protein polymer catabolic process|activation of protein depolymerization|positive regulation of protein polymer degradation|up regulation of protein polymer degradation|up regulation of protein polymer catabolic process|up-regulation of protein polymer catabolism|up-regulation of protein depolymerization|up regulation of protein depolymerization							rl	2013-02-06T13:57:32Z					biological_process											owl:Class	
GO:0000468	biolink:NamedThing	generation of mature 3'-end of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	Any process involved in generating the mature 3'-end of an LSU-rRNA derived from a tricistronic rRNA transcript that contained the Small SubUnit (SSU) rRNA, the 5.8S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript.	tmpzr1t_l9r_go_relaxed.owl	processing at B2													biological_process											owl:Class	
GO:0000463	biolink:NamedThing	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	Any process involved in the maturation of a precursor Large SubUnit (LSU) ribosomal RNA (rRNA) molecule into a mature LSU-rRNA molecule from the pre-rRNA molecule originally produced as a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, 5.8S rRNA, and Large Subunit (LSU) in that order from 5' to 3' along the primary transcript.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0098955	biolink:NamedThing	intrinsic component of presynaptic endosome membrane	The component of the presynaptic endosome membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.	tmpzr1t_l9r_go_relaxed.owl	intrinsic to presynaptic endosome membrane													cellular_component											owl:Class	
GO:0098954	biolink:NamedThing	presynaptic endosome membrane	The lipid bilayer surrounding a presynaptic endosome.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0005968	biolink:NamedThing	Rab-protein geranylgeranyltransferase complex	An protein-containing complex which catalyzes of the transfer of a geranyl-geranyl group from geranylgeranyl pyrophosphate to a Rab protein. In mammals it is composed of an alpha and a beta subunit, and associates with an accessory protein Rep (Rab escort protein).	tmpzr1t_l9r_go_relaxed.owl	GGTase-II complex|Rab geranylgeranyltransferase complex|RabGGTase complex													cellular_component											owl:Class	
GO:0032421	biolink:NamedThing	stereocilium bundle	A bundle of cross-linked stereocilia, arranged around a kinocilium on the apical surface of a sensory hair cell (e.g. a neuromast, auditory or vestibular hair cell). Stereocilium bundles act as mechanosensory organelles by responding to fluid motion or fluid pressure changes.	tmpzr1t_l9r_go_relaxed.owl	stereocilia bundle													cellular_component											owl:Class	
GO:0120061	biolink:NamedThing	negative regulation of gastric emptying	Any process that decreases the frequency, rate or extent of any gastric emptying process, the process in which the liquid and liquid-suspended solid contents of the stomach exit through the pylorus into the duodenum.	tmpzr1t_l9r_go_relaxed.owl								krc	2017-06-13T21:54:49Z					biological_process											owl:Class	
GO:0021716	biolink:NamedThing	inferior olivary nucleus structural organization	The process that contributes to the act of creating the structural organization of the inferior olivary nucleus structure. The inferior olivary nucleus is a capsule-shaped structure in the ventral medulla located just lateral and dorsal to the medullary pyramids. Neurons in the inferior olivary nucleus are the source of climbing fiber input to the cerebellar cortex; these neurons have been implicated in various functions, such as learning and timing of movements.	tmpzr1t_l9r_go_relaxed.owl	inferior olivary nucleus structural organisation|inferior olive structural organization													biological_process											owl:Class	
GO:0021581	biolink:NamedThing	medulla oblongata structural organization	The process that contributes to the act of creating the structural organization of the medulla oblongata. This process pertains to the physical shaping of a rudimentary structure. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate.	tmpzr1t_l9r_go_relaxed.owl	medulla oblongata structural organisation|myelencephalon structural maturation|medulla structural maturation													biological_process											owl:Class	
GO:0062021	biolink:NamedThing	mitotic cohesin dsDNA (leading strand) loading	The protein localization to chromatin by which a cohesin ring complex is topologically linked to dsDNA (leading strand) as part of the mitotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl								dph	2018-04-06T13:04:41Z					biological_process											owl:Class	
GO:0106126	biolink:NamedThing	reservosome membrane	The lipid bilayer surrounding a reservosome.	tmpzr1t_l9r_go_relaxed.owl								hjd	2018-05-03T18:01:26Z					cellular_component											owl:Class	
GO:0106123	biolink:NamedThing	reservosome	A large membrane-bound endocytic organelle present only in members of the Schizotrypanum subgenus of the Trypanosoma genus and is defined as the site of storage of endocytosed macromolecules and lysosomal enzymes. It is found at the posterior end of epimastigote forms of Trypanosoma cruzi, but absent in amastigotes and trypomastigotes.	tmpzr1t_l9r_go_relaxed.owl								hjd	2018-05-03T17:48:59Z					cellular_component											owl:Class	
GO:0032286	biolink:NamedThing	central nervous system myelin maintenance	The process in which the structure and material content of mature central nervous system myelin is kept in a functional state.	tmpzr1t_l9r_go_relaxed.owl	myelin maintenance in central nervous system													biological_process											owl:Class	
GO:1904794	biolink:NamedThing	negative regulation of euchromatin binding	Any process that stops, prevents or reduces the frequency, rate or extent of euchromatin binding.	tmpzr1t_l9r_go_relaxed.owl	inhibition of euchromatin binding|downregulation of euchromatin binding|down regulation of euchromatin binding|down-regulation of euchromatin binding							nc	2015-11-09T11:43:12Z					biological_process											owl:Class	
GO:1990188	biolink:NamedThing	euchromatin binding	Binding to euchromatin, a dispersed and relatively uncompacted form of chromatin.	tmpzr1t_l9r_go_relaxed.owl								tb	2013-09-11T19:18:38Z					molecular_function											owl:Class	
GO:1900314	biolink:NamedThing	positive regulation of maltohexaose transport	Any process that activates or increases the frequency, rate or extent of maltohexaose transport.	tmpzr1t_l9r_go_relaxed.owl	upregulation of maltohexaose transport|up regulation of maltohexaose transport|up-regulation of maltohexaose transport|activation of maltohexaose transport							tt	2012-04-05T07:59:35Z					biological_process											owl:Class	
GO:0061326	biolink:NamedThing	renal tubule development	The progression of the renal tubule over time from its formation to the mature form. A renal tubule is a tube that filters, re-absorbs and secretes substances to rid an organism of waste and to play a role in fluid homeostasis.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-09-28T12:50:43Z					biological_process											owl:Class	
GO:0072045	biolink:NamedThing	convergent extension involved in nephron morphogenesis	The morphogenetic process in which the renal epithelium narrows along one axis and lengthens in a perpendicular axis that contributes to the shaping of a nephron.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-01-25T03:22:47Z					biological_process											owl:Class	
GO:0005946	biolink:NamedThing	alpha,alpha-trehalose-phosphate synthase complex (UDP-forming)	A protein complex that possesses alpha,alpha-trehalose-phosphate synthase (UDP-forming) and trehalose-phosphatase activities, and thus catalyzes two reactions in trehalose biosynthesis. In the complex identified in Saccharomyces, Tps1p has alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity, Tps2p has trehalose 6-phosphate phosphatase activity; Tps3p is a regulatory subunit, and an additional subunit, Tsl1p, may be present.	tmpzr1t_l9r_go_relaxed.owl	trehalose-6-phosphate synthase complex|trehalose-6-phosphate synthase/phosphatase|UDP-glucose-glucosephosphate glucosyltransferase complex					See also the molecular function term 'alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity ; GO:0003825'.								cellular_component											owl:Class	
GO:0072037	biolink:NamedThing	mesenchymal stem cell differentiation involved in nephron morphogenesis	The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal stem cell that contributes to the shaping of a nephron. A mesenchymal stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-01-25T03:07:39Z					biological_process											owl:Class	
GO:0035712	biolink:NamedThing	T-helper 2 cell activation	The change in morphology and behavior of a T helper 2 cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.	tmpzr1t_l9r_go_relaxed.owl	Th2 cell activation							bf	2011-03-02T03:05:59Z					biological_process											owl:Class	
GO:0075288	biolink:NamedThing	negative regulation of sporangiospore formation	Any process that stops, prevents, or reduces the frequency, rate or extent of sporangiospore formation, a process in which sporangiospores, a type of asexual spore found in fungi, are formed. Sporangiospores are formed within sac-like structure, the sporangium, following the division of the cytoplasm.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:2000041	biolink:NamedThing	negative regulation of planar cell polarity pathway involved in axis elongation	Any process that stops, prevents, or reduces the frequency, rate or extent of planar cell polarity pathway involved in axis elongation.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-08-18T02:47:54Z					biological_process											owl:Class	
GO:1905216	biolink:NamedThing	positive regulation of RNA binding	Any process that activates or increases the frequency, rate or extent of RNA binding.	tmpzr1t_l9r_go_relaxed.owl	upregulation of RNA binding|up-regulation of RNA binding|activation of RNA binding|up regulation of RNA binding							bf	2016-06-06T10:21:12Z					biological_process											owl:Class	
GO:0005898	biolink:NamedThing	interleukin-13 receptor complex	A protein complex that binds interleukin-13; consists of two chains, interleukin-13 receptor alpha1 chain and interleukin-4 receptor alpha chain.	tmpzr1t_l9r_go_relaxed.owl	IL-13 receptor complex													cellular_component											owl:Class	
GO:0055127	biolink:NamedThing	vibrational conductance of sound to the inner ear	The transmission of vibrations via ossicles to the inner ear.	tmpzr1t_l9r_go_relaxed.owl								jid	2009-10-13T10:59:39Z					biological_process											owl:Class	
GO:0007605	biolink:NamedThing	sensory perception of sound	The series of events required for an organism to receive an auditory stimulus, convert it to a molecular signal, and recognize and characterize the signal. Sonic stimuli are detected in the form of vibrations and are processed to form a sound.	tmpzr1t_l9r_go_relaxed.owl	perception of sound|hearing				Wikipedia:Hearing_(sense)									biological_process											owl:Class	
GO:0097048	biolink:NamedThing	dendritic cell apoptotic process	Any apoptotic process in a dendritic cell, a cell of hematopoietic origin, typically resident in particular tissues, specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation.	tmpzr1t_l9r_go_relaxed.owl	dendritic cell apoptosis							pr	2011-05-04T02:18:59Z					biological_process											owl:Class	
GO:0005793	biolink:NamedThing	endoplasmic reticulum-Golgi intermediate compartment	A complex system of membrane-bounded compartments located between endoplasmic reticulum (ER) and the Golgi complex, with a distinctive membrane protein composition; involved in ER-to-Golgi  and Golgi-to-ER transport.	tmpzr1t_l9r_go_relaxed.owl	VTC|vesicular-tubular cluster|EGTC|ER-Golgi transport container|ER-Golgi intermediate compartment|pre-Golgi intermediate compartment|endoplasmic reticulum-Golgi transport container|ERGIC				Wikipedia:Vesicular-tubular_cluster									cellular_component											owl:Class	
GO:0061073	biolink:NamedThing	ciliary body morphogenesis	The process in which the ciliary body generated and organized. The ciliary body is the circumferential tissue inside the eye composed of the ciliary muscle and ciliary processes.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-03-16T10:55:19Z					biological_process											owl:Class	
GO:0046884	biolink:NamedThing	follicle-stimulating hormone secretion	The regulated release of follicle-stimulating hormone, a gonadotropic glycoprotein hormone secreted by the anterior pituitary.	tmpzr1t_l9r_go_relaxed.owl	follitropin secretion|follicle stimulating hormone secretion|FSH secretion													biological_process											owl:Class	
GO:0045647	biolink:NamedThing	negative regulation of erythrocyte differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of erythrocyte differentiation.	tmpzr1t_l9r_go_relaxed.owl	inhibition of erythrocyte differentiation|downregulation of erythrocyte differentiation|down regulation of erythrocyte differentiation|negative regulation of RBC differentiation|down-regulation of erythrocyte differentiation|negative regulation of red blood cell differentiation													biological_process											owl:Class	
GO:0032614	biolink:NamedThing	interleukin-11 production	The appearance of interleukin-11 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	tmpzr1t_l9r_go_relaxed.owl	IL-11 production|interleukin-11 biosynthetic process|interleukin-11 secretion											GO:0072609|GO:0042230		biological_process											owl:Class	
GO:0001726	biolink:NamedThing	ruffle	Projection at the leading edge of a crawling cell; the protrusions are supported by a microfilament meshwork.	tmpzr1t_l9r_go_relaxed.owl	membrane ruffle													cellular_component											owl:Class	
GO:0034087	biolink:NamedThing	establishment of mitotic sister chromatid cohesion	The process in which the sister chromatids of a replicated chromosome become joined along the entire length of the chromosome during S phase during a mitotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0031150	biolink:NamedThing	sorocarp stalk development	The process whose specific outcome is the progression of the sorocarp stalk over time, from its formation to the mature structure. The sorocarp stalk is a tubular structure that consists of cellulose-covered cells stacked on top of each other and surrounded by an acellular stalk tube composed of cellulose and glycoprotein. An example of this process is found in Dictyostelium discoideum.	tmpzr1t_l9r_go_relaxed.owl	stalk formation|sorophore development|stalk development													biological_process											owl:Class	
GO:0031154	biolink:NamedThing	culmination involved in sorocarp development	The process whose specific outcome is the progression of the culminant over time, from its formation to the mature structure. Culmination begins with a morphogenetic change of the finger-like or migratory slug giving rise to an organized structure containing a stalk and a sorus. This process is the final stage of sorocarp development.	tmpzr1t_l9r_go_relaxed.owl	culmination during fruiting body development|culminant development|culmination during sorocarp development													biological_process											owl:Class	
GO:0099588	biolink:NamedThing	positive regulation of postsynaptic cytosolic calcium concentration	Any process that increases the concentration of calcium ions in the postsynaptic cytosol.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0044290	biolink:NamedThing	mitochondrial intracristal space	The space bounded by the mitochondrial cristae membranes, continuous with the intermembrane space.	tmpzr1t_l9r_go_relaxed.owl					NIF_Subcellular:sao508958414			jl	2010-02-04T02:32:10Z					cellular_component											owl:Class	
GO:0002515	biolink:NamedThing	B cell anergy	Any process contributing to anergy in B cells, a state of functional inactivation which is part of B cell tolerance induction.	tmpzr1t_l9r_go_relaxed.owl	B-cell anergy|B-lymphocyte anergy|B lymphocyte anergy													biological_process											owl:Class	
GO:0072272	biolink:NamedThing	proximal/distal pattern formation involved in metanephric nephron development	The regionalization process in which specific areas of cell differentiation are determined along a proximal/distal axis of a nephron in the metanephros. The proximal/distal axis is defined by a line that runs from the center of the kidney (proximal end) outward (distal end).	tmpzr1t_l9r_go_relaxed.owl	proximal/distal metanephric nephron patterning|proximal-distal pattern formation involved in metanephric nephron development							mah	2010-03-30T03:25:37Z					biological_process											owl:Class	
GO:2000764	biolink:NamedThing	positive regulation of semaphorin-plexin signaling pathway involved in outflow tract morphogenesis	Any process that activates or increases the frequency, rate or extent of semaphorin-plexin signaling pathway involved in outflow tract morphogenesis.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of semaphorin-plexin signalling pathway involved in outflow tract morphogenesis							vk	2011-06-18T04:26:00Z					biological_process											owl:Class	
GO:0071527	biolink:NamedThing	semaphorin-plexin signaling pathway involved in outflow tract morphogenesis	A series of molecular signals generated as a consequence of a semaphorin receptor (composed of a plexin and a neurophilin) binding to a semaphorin ligand that contributes to outflow tract morphogenesis.	tmpzr1t_l9r_go_relaxed.owl	semaphorin-plexin signalling pathway involved in outflow tract morphogenesis							mah	2010-01-07T03:49:33Z					biological_process											owl:Class	
GO:1900048	biolink:NamedThing	positive regulation of hemostasis	Any process that activates or increases the frequency, rate or extent of hemostasis.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of hemostasis|up regulation of hemostasis|activation of hemostasis|upregulation of hemostasis							jl	2012-01-19T03:23:45Z					biological_process											owl:Class	
GO:0007599	biolink:NamedThing	hemostasis	The stopping of bleeding (loss of body fluid) or the arrest of the circulation to an organ or part.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Hemostasis									biological_process											owl:Class	
GO:0120213	biolink:NamedThing	regulation of histidine biosynthetic process	Any process that modulates the frequency, rate or extent of histidine biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of histidine formation|regulation of histidine biosynthesis|regulation of histidine synthesis|regulation of histidine anabolism							krc	2019-06-27T20:55:42Z					biological_process											owl:Class	
GO:0000105	biolink:NamedThing	histidine biosynthetic process	The chemical reactions and pathways resulting in the formation of histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid.	tmpzr1t_l9r_go_relaxed.owl	histidine formation|histidine biosynthesis|histidine anabolism|histidine synthesis				MetaCyc:HISTSYN-PWY									biological_process											owl:Class	
GO:0009738	biolink:NamedThing	abscisic acid-activated signaling pathway	A series of molecular signals generated by the binding of the plant hormone abscisic acid (ABA) to a receptor, and ending with modulation of a cellular process, e.g. transcription.	tmpzr1t_l9r_go_relaxed.owl	abscisic acid signal transduction|ABA signal transduction|abscisic acid-mediated signaling pathway|abscisic acid mediated signalling|ABA signaling													biological_process											owl:Class	
GO:0010636	biolink:NamedThing	positive regulation of mitochondrial fusion	Any process that increases the frequency, rate or extent of merging of two or more mitochondria within a cell to form a single compartment.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0008053	biolink:NamedThing	mitochondrial fusion	Merging of two or more mitochondria within a cell to form a single compartment.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0140691	biolink:NamedThing	RNA folding chaperone	Binding to an RNA or an RNA-containing complex to assist the folding process.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/21913						pg	2021-08-04T07:48:29Z					molecular_function											owl:Class	
GO:0034337	biolink:NamedThing	RNA folding	The process of assisting in the covalent and noncovalent assembly of single or multimeric RNAs into the correct tertiary structure.	tmpzr1t_l9r_go_relaxed.owl	RNA chaperone													biological_process											owl:Class	
GO:1902315	biolink:NamedThing	nuclear cell cycle DNA replication initiation	Any DNA replication initiation that is involved in nuclear cell cycle DNA replication.	tmpzr1t_l9r_go_relaxed.owl	DNA re-replication initiation involved in nuclear cell cycle DNA replication|DNA endoreduplication initiation involved in nuclear cell cycle DNA replication|DNA replication initiation involved in nuclear cell cycle DNA replication							jl	2013-07-23T14:00:01Z					biological_process											owl:Class	
GO:0007393	biolink:NamedThing	dorsal closure, leading edge cell fate determination	The cell fate determination process in which a cell within the dorsal ectoderm becomes capable of differentiating autonomously into a leading edge cell regardless of its environment; upon determination, the cell fate cannot be reversed.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0022604	biolink:NamedThing	regulation of cell morphogenesis	Any process that modulates the frequency, rate or extent of cell morphogenesis. Cell morphogenesis is the developmental process in which the shape of a cell is generated and organized.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of cell shape and cell size|regulation of cell shape and cell size|positive regulation of cell shape and cell size													biological_process											owl:Class	
GO:0032629	biolink:NamedThing	interleukin-25 production	The appearance of interleukin-25 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	tmpzr1t_l9r_go_relaxed.owl	interleukin-25 formation|interleukin-25 biosynthetic process|interleukin-25 synthesis|interleukin-25 biosynthesis|IL-25 production|interleukin-25 anabolism|interleukin-25 secretion|IL-25 secretion|IL17E secretion											GO:0072623|GO:0045525		biological_process											owl:Class	
GO:1904372	biolink:NamedThing	positive regulation of protein localization to actin cortical patch	Any process that activates or increases the frequency, rate or extent of protein localization to actin cortical patch.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of protein localisation to actin cortical patch|up regulation of protein localisation to actin cortical patch|upregulation of protein localisation to actin cortical patch|activation of protein localization to actin cortical patch|upregulation of protein localization to actin cortical patch|up regulation of protein localization to actin cortical patch|activation of protein localisation to actin cortical patch|up-regulation of protein localization to actin cortical patch|up-regulation of protein localisation to actin cortical patch							sl	2015-06-18T22:23:43Z					biological_process											owl:Class	
GO:0019245	biolink:NamedThing	D(-)-lactate biosynthetic process from pyruvate	The chemical reactions and pathways resulting in the formation of D(-)-lactate from other compounds, including pyruvate.	tmpzr1t_l9r_go_relaxed.owl	D(-)-lactate formation from pyruvate|D(-)-lactate anabolism from pyruvate|D(-)-lactate synthesis from pyruvate													biological_process											owl:Class	
GO:0031835	biolink:NamedThing	substance P receptor binding	Binding to a substance P receptor.	tmpzr1t_l9r_go_relaxed.owl	substance P receptor ligand|neurokinin-1 receptor binding													molecular_function											owl:Class	
GO:0060844	biolink:NamedThing	arterial endothelial cell fate commitment	The commitment of a cell to an arterial endothelial cell fate and its capacity to differentiate into an arterial endothelial cell.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-08-12T10:49:00Z					biological_process											owl:Class	
GO:0060842	biolink:NamedThing	arterial endothelial cell differentiation	The process in which a relatively unspecialized endothelial cell acquires specialized features of an arterial endothelial cell, a thin flattened cell that lines the inside surfaces of arteries.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-08-12T10:41:34Z					biological_process											owl:Class	
GO:0032822	biolink:NamedThing	positive regulation of natural killer cell proliferation involved in immune response	Any process that activates or increases the frequency, rate or extent of natural killer cell proliferation as part of an immune response.	tmpzr1t_l9r_go_relaxed.owl	up regulation of natural killer cell proliferation during immune response|up-regulation of natural killer cell proliferation during immune response|positive regulation of natural killer cell proliferation during immune response|positive regulation of NK cell proliferation during immune response|stimulation of natural killer cell proliferation during immune response|activation of natural killer cell proliferation during immune response|upregulation of natural killer cell proliferation during immune response													biological_process											owl:Class	
GO:0097197	biolink:NamedThing	tetraspanin-enriched microdomain	A pre-organized unit composed either of adhesion molecules (mainly integrins and members of the Ig superfamily), signaling receptors and/or enzyme-enriched plasma membrane domains that compartmentalizes cellular processes. Tetraspanin-enriched microdomains might be specially suited for the regulation of avidity of adhesion receptors and the compartmentalization of enzymatic activities.	tmpzr1t_l9r_go_relaxed.owl	TEM|membrane tetraspanin-enriched microdomain							pr	2011-12-02T04:21:37Z					cellular_component											owl:Class	
GO:1901146	biolink:NamedThing	mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis	Any mesenchymal cell apoptotic process that is involved in mesonephric nephron morphogenesis.	tmpzr1t_l9r_go_relaxed.owl								pr	2012-07-13T02:40:43Z					biological_process											owl:Class	
GO:0071012	biolink:NamedThing	catalytic step 1 spliceosome	A spliceosomal complex that is formed by the displacement of the two snRNPs from the precatalytic spliceosome; three snRNPs including U5 remain associated with the mRNA. This complex, sometimes called the activated spliceosome, is the catalytically active form of the spliceosome, and includes many proteins in addition to those found in the associated snRNPs.	tmpzr1t_l9r_go_relaxed.owl	mammalian spliceosomal complex B*|yeast spliceosomal complex A1|activated spliceosome|mammalian spliceosomal complex B2							mah	2009-07-30T12:00:35Z					cellular_component											owl:Class	
GO:0000974	biolink:NamedThing	Prp19 complex	A protein complex consisting of Prp19 and associated proteins that is involved in the transition from the precatalytic spliceosome to the activated form that catalyzes step 1 of splicing, and which remains associated with the spliceosome through the second catalytic step. It is widely conserved, found in both yeast and mammals, though the exact composition varies. In S. cerevisiae, it contains Prp19p, Ntc20p, Snt309p, Isy1p, Syf2p, Cwc2p, Prp46p, Clf1p, Cef1p, and Syf1p.	tmpzr1t_l9r_go_relaxed.owl	NTC|Prp19/CDC5 complex|nineteen complex							krc	2009-10-12T10:01:30Z					cellular_component											owl:Class	
GO:0099579	biolink:NamedThing	G protein-coupled neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential	A G protein-coupled neurotransmitter receptor activity, occurring in the postsynaptic membrane, involved in regulation of postsynaptic membrane potential.	tmpzr1t_l9r_go_relaxed.owl	G-protein coupled neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential													molecular_function											owl:Class	
GO:0009577	biolink:NamedThing	elaioplast stroma	The space enclosed by the double membrane of an elaioplast.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0009545	biolink:NamedThing	elaioplast	A leucoplast in which oil is stored.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Elaioplast									cellular_component											owl:Class	
GO:1902026	biolink:NamedThing	regulation of cartilage condensation	Any process that modulates the frequency, rate or extent of cartilage condensation.	tmpzr1t_l9r_go_relaxed.owl								jl	2013-03-28T17:02:42Z					biological_process											owl:Class	
GO:0001502	biolink:NamedThing	cartilage condensation	The condensation of mesenchymal cells that have been committed to differentiate into chondrocytes.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0045751	biolink:NamedThing	negative regulation of Toll signaling pathway	Any process that stops, prevents, or reduces the frequency, rate or extent of the Tl signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	downregulation of Toll signaling pathway|inhibition of Toll signaling pathway|down-regulation of Toll signaling pathway|negative regulation of Tl signalling pathway|down regulation of Toll signaling pathway|negative regulation of Tl signaling pathway													biological_process											owl:Class	
GO:0008063	biolink:NamedThing	Toll signaling pathway	A series of molecular signals initiated by the binding of an extracellular ligand to the receptor Toll on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.	tmpzr1t_l9r_go_relaxed.owl	Toll signalling pathway|Tl signalling pathway|Tl signaling pathway													biological_process											owl:Class	
GO:0021917	biolink:NamedThing	somatic motor neuron fate commitment	The commitment of unspecified motor neurons to specific motor neuron cell along the anterior-posterior axis of the spinal cord and their capacity to differentiate into specific motor neurons.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0021523	biolink:NamedThing	somatic motor neuron differentiation	The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of somatic motor neurons. Somatic motor neurons innervate skeletal muscle targets and are responsible for transmission of motor impulses from the brain to the periphery. Differentiation includes the processes involved in commitment of a cell to a specific fate.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1900157	biolink:NamedThing	regulation of bone mineralization involved in bone maturation	Any process that modulates the frequency, rate or extent of bone mineralization involved in bone maturation.	tmpzr1t_l9r_go_relaxed.owl								vk	2012-03-07T08:55:07Z					biological_process											owl:Class	
GO:0060035	biolink:NamedThing	notochord cell development	The process whose specific outcome is the progression of a notochord cell over time, from its formation to its mature structure. Cell development does not include the steps involved in committing a cell to a specific fate.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0090244	biolink:NamedThing	Wnt signaling pathway involved in somitogenesis	The series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of the target cell and ending with a change in cell state that contributes to somitogenesis.	tmpzr1t_l9r_go_relaxed.owl	Wnt receptor signaling pathway involved in somitogenesis|Wnt-activated signaling pathway involved in somitogenesis|Wnt receptor signalling							tb	2010-01-22T10:47:59Z					biological_process											owl:Class	
GO:0034715	biolink:NamedThing	pICln-Sm protein complex	A protein complex that contains pICln (CLNS1A) and several Sm proteins, including SmD1, SmD2, SmE, SmF, and SmG.	tmpzr1t_l9r_go_relaxed.owl	6S pICln complex													cellular_component											owl:Class	
GO:0072322	biolink:NamedThing	protein transport across periplasmic space	The directed movement of proteins from the plasma membrane across the periplasmic space to the outer membrane or cell wall.	tmpzr1t_l9r_go_relaxed.owl	chaperone-mediated protein transport across periplasmic space	https://github.com/geneontology/go-ontology/issues/15917						mah	2010-10-28T04:24:59Z			GO:0072323		biological_process											owl:Class	
GO:1901432	biolink:NamedThing	negative regulation of response to cycloalkane	Any process that stops, prevents or reduces the frequency, rate or extent of response to cycloalkane.	tmpzr1t_l9r_go_relaxed.owl	downregulation of response to cycloalkane|down-regulation of response to cycloalkane|inhibition of response to cycloalkane|down regulation of response to cycloalkane							tt	2012-10-01T21:03:08Z					biological_process											owl:Class	
GO:0042693	biolink:NamedThing	muscle cell fate commitment	The process in which the cellular identity of muscle cells is acquired and determined.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0043928	biolink:NamedThing	exonucleolytic catabolism of deadenylated mRNA	The chemical reactions and pathways resulting in the breakdown of the transcript body of a nuclear-transcribed mRNA that occurs when the ends are not protected by the 3'-poly(A) tail.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0048725	biolink:NamedThing	cibarial fish-trap bristle development	The process whose specific outcome is the progression of the cibarial fish-trap bristle over time, from its formation to the mature structure. A cibarial fish-trap bristle is a sensory bristle on the anterior plate of the cibarium.	tmpzr1t_l9r_go_relaxed.owl	fish-trap bristle development													biological_process											owl:Class	
GO:1900935	biolink:NamedThing	regulation of nonadec-1-ene biosynthetic process	Any process that modulates the frequency, rate or extent of nonadec-1-ene biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of nonadec-1-ene formation|regulation of nonadec-1-ene biosynthesis|regulation of nonadec-1-ene anabolism|regulation of nonadec-1-ene synthesis							tt	2012-06-14T03:13:34Z					biological_process											owl:Class	
GO:0002176	biolink:NamedThing	male germ cell proliferation	The multiplication or reproduction of male germ cells, resulting in the expansion of a cell population.	tmpzr1t_l9r_go_relaxed.owl								hjd	2010-11-18T02:35:14Z					biological_process											owl:Class	
GO:0039703	biolink:NamedThing	RNA replication	The cellular metabolic process in which a cell duplicates one or more molecules of RNA.	tmpzr1t_l9r_go_relaxed.owl								bf	2013-11-21T16:53:29Z					biological_process											owl:Class	
GO:0003061	biolink:NamedThing	positive regulation of the force of heart contraction by norepinephrine	The process in which the secretion of norepinephrine into the bloodstream or released from nerve endings modulates the force of heart musclecontraction.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of heart contraction by norepinephrine|increased force of heart contraction by adrenaline|increased force of heart contraction by norepinephrine|noradrenaline regulation of the strength of heart muscle contraction|norepinephrine cardiac inotropy|noradrenaline cardiac inotropy|positive regulation of heart contraction by adrenaline													biological_process											owl:Class	
GO:0035670	biolink:NamedThing	plant-type ovary development	The process whose specific outcome is the progression of an ovary that produces an ovule over time, from its formation to the mature structure. The ovary is the enlarged basal portion of a carpel and matures into a fruit. An ovule is the multicellular structure that gives rise to and contains the female reproductive cells, and develops into a seed.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-02-04T09:35:05Z					biological_process											owl:Class	
GO:0001667	biolink:NamedThing	ameboidal-type cell migration	Cell migration that is accomplished by extension and retraction of a pseudopodium.	tmpzr1t_l9r_go_relaxed.owl	amoeboidal cell migration|amoeboid cell migration|ameboid cell migration					Note that this term refers to a mode of migration rather than to any particular cell type.								biological_process											owl:Class	
GO:0060977	biolink:NamedThing	coronary vasculature morphogenesis	The process in which the anatomical structures of blood vessels of the heart are generated and organized. The blood vessel is the vasculature carrying blood.	tmpzr1t_l9r_go_relaxed.owl	cardiac blood vessel morphogenesis|heart vasculature morphogenesis|coronary blood vessel morphogenesis|cardiac vasculature morphogenesis|heart blood vessel morphogenesis							dph	2009-10-06T12:28:23Z					biological_process											owl:Class	
GO:0031059	biolink:NamedThing	histone deacetylation at centromere	The removal of acetyl groups from histones in centromeric DNA.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0042689	biolink:NamedThing	regulation of crystal cell differentiation	Any process that modulates the frequency, rate or extent of crystal cell differentiation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0070120	biolink:NamedThing	ciliary neurotrophic factor-mediated signaling pathway	A series of molecular signals initiated by the binding of a ciliary neurotrophic factor (CNTF) to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.	tmpzr1t_l9r_go_relaxed.owl	CNTF-mediated signaling pathway|ciliary neurotrophic factor-mediated signalling pathway													biological_process											owl:Class	
GO:1901620	biolink:NamedThing	regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning	Any process that modulates the frequency, rate or extent of smoothened signaling pathway involved in dorsal/ventral neural tube patterning.	tmpzr1t_l9r_go_relaxed.owl	regulation of smoothened signalling pathway involved in dorsal/ventral neural tube patterning|regulation of hedgehog signaling pathway involved in dorsal/ventral neural tube patterning|regulation of hh signaling pathway involved in dorsal/ventral neural tube patterning							krc	2012-11-13T20:11:57Z					biological_process											owl:Class	
GO:0045431	biolink:NamedThing	flavonol synthase activity	Catalysis of the reaction: a dihydroflavonol + 2-oxoglurate + O2 = a flavonol + succinate + CO2 + H2O.	tmpzr1t_l9r_go_relaxed.owl	flavonoid 2-oxoglutarate-dependent dioxygenase activity|FLS activity|dihydroflavonol,2-oxoglutarate:oxygen oxidoreductase activity				EC:1.14.20.6|RHEA:21088									molecular_function											owl:Class	
GO:0071008	biolink:NamedThing	U2-type post-mRNA release spliceosomal complex	A spliceosomal complex that is formed following the release of the spliced product from the post-spliceosomal complex and contains the excised intron and the U2, U5 and U6 snRNPs.	tmpzr1t_l9r_go_relaxed.owl	major post-mRNA release spliceosomal complex|U2/U5/U6 snRNP complex|U2/U5/U6 tri-snRNP complex|GT-AG post-mRNA release spliceosomal complex|mammalian U2-type spliceosomal complex I							mah	2009-07-30T12:00:35Z					cellular_component											owl:Class	
GO:1904472	biolink:NamedThing	positive regulation of endothelin production	Any process that activates or increases the frequency, rate or extent of endothelin production.	tmpzr1t_l9r_go_relaxed.owl	up regulation of EDN1 secretion|upregulation of EDN3 secretion|up-regulation of endothelin secretion|up-regulation of EDN1 secretion|upregulation of EDN1 secretion|positive regulation of endothelin-3 secretion|upregulation of endothelin secretion|positive regulation of endothelin secretion|upregulation of endothelin-2 secretion|positive regulation of endothelin-2 secretion|activation of endothelin secretion|activation of EDN2 secretion|up-regulation of EDN2 secretion|activation of EDN3 secretion|positive regulation of EDN1 secretion|up regulation of endothelin-2 secretion|up regulation of EDN2 secretion|upregulation of endothelin-3 secretion|positive regulation of endothelin-1 secretion|up regulation of endothelin secretion|up-regulation of EDN3 secretion|up-regulation of endothelin-1 secretion|positive regulation of EDN3 secretion|up regulation of EDN3 secretion|up regulation of endothelin-3 secretion|up-regulation of endothelin-3 secretion|activation of EDN1 secretion|activation of endothelin-1 secretion|positive regulation of EDN2 secretion|activation of endothelin-2 secretion|activation of endothelin-3 secretion|upregulation of endothelin-1 secretion|upregulation of EDN2 secretion|up-regulation of endothelin-2 secretion|up regulation of endothelin-1 secretion							sl	2015-07-09T19:58:10Z					biological_process											owl:Class	
GO:1990775	biolink:NamedThing	endothelin production	The appearance of a endothelin due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Endothelins are endothelium-derived vasoactive peptides involved in a variety of biological functions.	tmpzr1t_l9r_go_relaxed.owl	endothelin-1 secretion|EDN3 production|EDN1 production|endothelin-2 production|EDN2 production|endothelin secretion|endothelin-3 production							sl	2015-06-15T23:13:18Z					biological_process											owl:Class	
GO:0071369	biolink:NamedThing	cellular response to ethylene stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ethylene (ethene) stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to ethene stimulus							mah	2009-12-11T03:13:57Z					biological_process											owl:Class	
GO:0072057	biolink:NamedThing	inner stripe development	The process whose specific outcome is the progression of the inner stripe over time, from its formation to the mature structure. The inner stripe is a deep, centrally located portion of the renal outer medulla and is traversed by thin descending and thick ascending portions of the loops of Henle.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-01-25T04:01:58Z					biological_process											owl:Class	
GO:0072054	biolink:NamedThing	renal outer medulla development	The process whose specific outcome is the progression of the renal outer medulla over time, from its formation to the mature structure. The renal outer medulla is the region of the kidney that lies between the renal cortex and the renal inner medulla.	tmpzr1t_l9r_go_relaxed.owl	outer renal medulla development							mah	2010-01-25T04:00:42Z					biological_process											owl:Class	
GO:0031619	biolink:NamedThing	homologous chromosome orientation involved in meiotic metaphase I plate congression	The cell cycle process in which the sister centromeres of one chromosome attach to microtubules that emanate from the same spindle pole, which ensures that homologous maternal and paternal chromosomes are pulled in opposite directions at anaphase of meiosis I.	tmpzr1t_l9r_go_relaxed.owl	homologous chromosome orientation during meiosis|homologous chromosome orientation during meiosis I													biological_process											owl:Class	
GO:0043060	biolink:NamedThing	meiotic metaphase I plate congression	The alignment of chromosomes at the metaphase plate, a plane halfway between the poles of the meiotic spindle, during meiosis I.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0021763	biolink:NamedThing	subthalamic nucleus development	The progression of the subthalamic nucleus over time from its initial formation until its mature state. The subthalamic nucleus is the lens-shaped nucleus located in the ventral part of the subthalamus on the inner aspect of the internal capsule that is concerned with the integration of somatic motor function.	tmpzr1t_l9r_go_relaxed.owl	corpus luysi development													biological_process											owl:Class	
GO:0021539	biolink:NamedThing	subthalamus development	The process whose specific outcome is the progression of the subthalamus over time, from its formation to the mature structure. The subthalamus is the anterior part of the diencephalon that lies between the thalamus, hypothalamus, and tegmentum of the mesencephalon, including subthalamic nucleus, zona incerta, the fields of Forel, and the nucleus of ansa lenticularis.	tmpzr1t_l9r_go_relaxed.owl	ventral thalamus development													biological_process											owl:Class	
GO:0020039	biolink:NamedThing	pellicle	The structure enclosing certain parasite cells such as certain apicomplexa and Euglenozoa; consists of the cell membrane with its associated infrastructure of microtubules, microfilaments and other organelles.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0060708	biolink:NamedThing	spongiotrophoblast differentiation	The process in which a relatively unspecialized cell of the ectoplacental cone acquires specialized features of a spongiotrophoblast of the placenta. A spongiotrophoblast cell is a basophilic cell.	tmpzr1t_l9r_go_relaxed.owl	spongiotrophoblast cell differentiation							dph	2009-06-09T10:38:10Z					biological_process											owl:Class	
GO:0120279	biolink:NamedThing	Z granule	A small cytoplasmic, non-membranous RNA/protein complex aggregate in the primordial germ cells that are distinct from, but colocalize with or are adjacent to, P granules and mutator foci and are associated with RNA metabolism. Z granules have been observed in C. elegans.	tmpzr1t_l9r_go_relaxed.owl	germline granule	https://github.com/geneontology/go-ontology/issues/20108						krc	2020-10-21T18:27:05Z					cellular_component											owl:Class	
GO:0060293	biolink:NamedThing	germ plasm	Differentiated cytoplasm associated with a pole of an oocyte, egg or early embryo that will be inherited by the cells that will give rise to the germ line.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Germ_plasm									cellular_component											owl:Class	
GO:1903570	biolink:NamedThing	regulation of protein kinase D signaling	Any process that modulates the frequency, rate or extent of protein kinase D signaling.	tmpzr1t_l9r_go_relaxed.owl	regulation of PKD signal transduction|regulation of PKD signaling cascade|regulation of protein kinase D signalling cascade|regulation of protein kinase D signaling cascade|regulation of protein kinase D signal transduction							rl	2014-10-27T15:18:00Z					biological_process											owl:Class	
GO:0052324	biolink:NamedThing	plant-type cell wall cellulose biosynthetic process	The chemical reactions and pathways resulting in the formation of cellulose, a linear beta1-4 glucan of molecular mass 50-400 kDa with the pyranose units in the -4C1 conformation, as part of the organization and biogenesis of the cell wall.	tmpzr1t_l9r_go_relaxed.owl	cell wall cellulose biosynthesis|cellulose biosynthesis during cell wall biosynthesis													biological_process											owl:Class	
GO:0048822	biolink:NamedThing	enucleate erythrocyte development	The process aimed at the progression of an enucleate erythrocyte over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.	tmpzr1t_l9r_go_relaxed.owl	enucleate red blood cell development|enucleate RBC development													biological_process											owl:Class	
GO:0043353	biolink:NamedThing	enucleate erythrocyte differentiation	The process in which a myeloid precursor cell acquires specialized features of an erythrocyte without a nucleus. An example of this process is found in Mus musculus.	tmpzr1t_l9r_go_relaxed.owl	enucleate red blood cell differentiation|enucleate RBC differentiation													biological_process											owl:Class	
GO:0051402	biolink:NamedThing	neuron apoptotic process	Any apoptotic process in a neuron, the basic cellular unit of nervous tissue. Each neuron consists of a body, an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the nervous system.	tmpzr1t_l9r_go_relaxed.owl	programmed cell death, neurons|neuron apoptosis|programmed cell death of neurons by apoptosis|apoptosis of neuronal cells|programmed cell death of neuronal cells by apoptosis|programmed cell death, neuronal cells|neuronal cell programmed cell death by apoptosis|neuron programmed cell death by apoptosis|neuronal cell apoptosis|apoptosis of neurons													biological_process											owl:Class	
GO:0021719	biolink:NamedThing	superior olivary nucleus morphogenesis	The process in which the anatomical structure of the superior olivary nucleus is generated and organized. In mice, the superior olivary nucleus is a small cylindrical mass on the dorsal surface of the lateral part of the trapezoid body of the pons, and it is situated immediately above the inferior olivary nucleus. It receives projections from the cochlear nucleus and thus is involved in the perception of sound.	tmpzr1t_l9r_go_relaxed.owl	superior olive morphogenesis													biological_process											owl:Class	
GO:1905291	biolink:NamedThing	positive regulation of CAMKK-AMPK signaling cascade	Any process that activates or increases the frequency, rate or extent of CAMKK-AMPK signaling cascade.	tmpzr1t_l9r_go_relaxed.owl	upregulation of CAMKK-AMPK signaling cascade|up regulation of stress-activated AMP-activated protein kinase signaling cascade|activation of stress-activated AMP-activated protein kinase signaling cascade|up-regulation of CAMKK-AMPK signaling cascade|up-regulation of stress-activated AMP-activated protein kinase signaling cascade|upregulation of stress-activated AMP-activated protein kinase signaling cascade|positive regulation of stress-activated AMP-activated protein kinase signaling cascade|up regulation of CAMKK-AMPK signaling cascade|activation of CAMKK-AMPK signaling cascade							sl	2016-06-23T20:37:10Z					biological_process											owl:Class	
GO:2001143	biolink:NamedThing	N-methylnicotinate transport	The directed movement of a N-methylnicotinateacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl								tb	2011-10-18T05:16:08Z					biological_process											owl:Class	
GO:0033382	biolink:NamedThing	maintenance of granzyme B location in T cell secretory granule	A process in which the protease granyme B is maintained in a secretory granule in a T cell and prevented from moving elsewhere.	tmpzr1t_l9r_go_relaxed.owl	maintenance of granzyme B localization in T cell secretory granule|maintenance of granzyme B localization in T-lymphocyte secretory granule|maintenance of granzyme B localization in T-cell secretory granule|maintenance of granzyme B localization in T lymphocyte secretory granule													biological_process											owl:Class	
GO:0033380	biolink:NamedThing	granzyme B localization to T cell secretory granule	Any process in which the protease granzyme B is transported to, or maintained in, a location within a secretory granule in a T cell.	tmpzr1t_l9r_go_relaxed.owl	granzyme B localization in T cell secretory granule|granzyme B localization in T lymphocyte secretory granule|granzyme B localization in T-lymphocyte secretory granule|granzyme B localisation in T cell secretory granule|granzyme B localization in T-cell secretory granule													biological_process											owl:Class	
GO:0042638	biolink:NamedThing	exogen	The shedding phase of the hair cycle.	tmpzr1t_l9r_go_relaxed.owl	hair shedding					Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase. To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).								biological_process											owl:Class	
GO:0048820	biolink:NamedThing	hair follicle maturation	A developmental process, independent of morphogenetic (shape) change, that is required for a hair follicle to attain its fully functional state.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1902986	biolink:NamedThing	regulation of lysine biosynthetic process via aminoadipic acid	Any process that modulates the frequency, rate or extent of lysine biosynthetic process via aminoadipic acid.	tmpzr1t_l9r_go_relaxed.owl	regulation of lysine biosynthesis, aminoadipic acid pathway|regulation of lysine formation via aminoadipic acid|regulation of lysine synthesis via aminoadipic acid|regulation of lysine anabolism via aminoadipic acid|regulation of lysine biosynthetic process, aminoadipic acid pathway|regulation of lysine biosynthetic process, aminoadipic pathway|regulation of lysine biosynthesis, aminoadipic pathway							al	2014-05-07T08:07:08Z					biological_process											owl:Class	
GO:0019878	biolink:NamedThing	lysine biosynthetic process via aminoadipic acid	The chemical reactions and pathways resulting in the formation of lysine by the aminoadipic pathway.	tmpzr1t_l9r_go_relaxed.owl	lysine biosynthetic process, aminoadipic pathway|lysine biosynthesis, aminoadipic pathway|lysine formation via aminoadipic acid|lysine biosynthesis, aminoadipic acid pathway|lysine synthesis via aminoadipic acid|lysine anabolism via aminoadipic acid|lysine biosynthetic process, aminoadipic acid pathway													biological_process											owl:Class	
GO:0044230	biolink:NamedThing	host cell envelope	An envelope that surrounds a bacterial host cell and includes the host cytoplasmic membrane and everything external, encompassing the host periplasmic space, host cell wall, and host outer membrane if present.	tmpzr1t_l9r_go_relaxed.owl								jl	2009-12-03T03:24:03Z					cellular_component											owl:Class	
GO:0075192	biolink:NamedThing	haustorium mother cell formation	The process in which a symbiont cell is formed, separated from the tip of an infection hypha by a septum. The haustorium mother cell usually contains 2-4 fungal nuclei, and its function is to attach and penetrate the host. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	haustorium mother cell formation on or near host					Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products from the symbiont involved in this process.								biological_process											owl:Class	
GO:0071036	biolink:NamedThing	nuclear polyadenylation-dependent snoRNA catabolic process	The chemical reactions and pathways occurring in the nucleus and resulting in the breakdown of a small nucleolar RNA (snoRNA) molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target snoRNA.	tmpzr1t_l9r_go_relaxed.owl	nuclear poly(A)-dependent snoRNA catabolic process							krc	2009-07-29T01:04:44Z					biological_process											owl:Class	
GO:0003244	biolink:NamedThing	radial growth involved in right ventricle morphogenesis	The morphogenic growth in which the right ventricle grows along a radial axis.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-10-13T11:38:23Z					biological_process											owl:Class	
GO:1990154	biolink:NamedThing	enzyme IIA-maltose transporter complex	A protein complex consisting of the pentameric maltose transporter complex bound to two enzyme IIA (EIIA) molecules. EIIA is a component of the glucose-specific phosphotransferase system that inhibits maltose transport from the periplasm to the cytoplasm. When EIIA-bound, the maltose transporter remains in the open, inward-facing conformation, which prevents binding of maltose-loaded maltose binding protein (MBP) to the transporter.	tmpzr1t_l9r_go_relaxed.owl	maltose transporter inhibitor complex|EIIA(Glc)-maltose transporter complex|EIIA(Glc)-MalFGK2 complex							bhm	2013-08-01T09:27:25Z					cellular_component											owl:Class	
GO:1904456	biolink:NamedThing	negative regulation of neuronal action potential	Any process that stops, prevents or reduces the frequency, rate or extent of neuronal action potential.	tmpzr1t_l9r_go_relaxed.owl	down regulation of generation of action potential|down-regulation of generation of action potential|down regulation of neuronal action potential|downregulation of neuronal action potential|negative regulation of generation of action potential|downregulation of generation of action potential|inhibition of generation of action potential|down-regulation of neuronal action potential|inhibition of neuronal action potential							sl	2015-07-09T18:02:40Z					biological_process											owl:Class	
GO:0021891	biolink:NamedThing	olfactory bulb interneuron development	The process whose specific outcome is the progression of an interneuron residing in the olfactory bulb, from its initial commitment, to the fully functional differentiated cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0046621	biolink:NamedThing	negative regulation of organ growth	Any process that stops, prevents, or reduces the frequency, rate or extent of growth of an organ of an organism.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0090094	biolink:NamedThing	metanephric cap mesenchymal cell proliferation involved in metanephros development	The multiplication or reproduction of metanephric cap mesenchymal cells, resulting in the expansion of the cell population. A metanephric cap mesenchymal cell is a mesenchymal cell that has condensed with other mesenchymal cells surrounding the ureteric bud tip.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-11-13T10:34:10Z					biological_process											owl:Class	
GO:0098566	biolink:NamedThing	transport vesicle lumen	The volume enclosed within the membrane of a transport vesicle.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0014808	biolink:NamedThing	release of sequestered calcium ion into cytosol by sarcoplasmic reticulum	The process in which the release of sequestered calcium ion by sarcoplasmic reticulum into cytosol occurs via calcium release channels.	tmpzr1t_l9r_go_relaxed.owl	release of sequestered calcium ion by sarcoplasmic reticulum into cytosol													biological_process											owl:Class	
GO:1900363	biolink:NamedThing	regulation of mRNA polyadenylation	Any process that modulates the frequency, rate or extent of mRNA polyadenylation.	tmpzr1t_l9r_go_relaxed.owl	regulation of mRNA polyadenylylation|regulation of cleavage and polyadenylylation specificity factor activity							pr	2012-04-12T04:36:21Z					biological_process											owl:Class	
GO:0006378	biolink:NamedThing	mRNA polyadenylation	The enzymatic addition of a sequence of 40-200 adenylyl residues at the 3' end of a eukaryotic mRNA primary transcript.	tmpzr1t_l9r_go_relaxed.owl	mRNA polyadenylylation|cleavage and polyadenylylation specificity factor activity													biological_process											owl:Class	
GO:0000177	biolink:NamedThing	cytoplasmic exosome (RNase complex)	A ribonuclease complex that has 3-prime to 5-prime processive hydrolytic exoribonuclease activity producing 5-prime-phosphomonoesters. Participates in a multitude of cellular RNA processing and degradation events preventing nuclear export and/or translation of aberrant RNAs. Restricted to processing linear and circular single-stranded RNAs (ssRNA) only. RNAs with complex secondary structures may have to be unwound or pre-processed by co-factors prior to entering the complex, esp if the 3-prime end is structured.	tmpzr1t_l9r_go_relaxed.owl	prokaryotic exosome multienzyme ribonuclease complex|cytoplasmic exosome multienzyme ribonuclease complex|cytoplasmic exosome (ribonuclease complex)													cellular_component											owl:Class	
GO:1902876	biolink:NamedThing	negative regulation of embryonic pattern specification	Any process that stops, prevents or reduces the frequency, rate or extent of embryonic pattern specification.	tmpzr1t_l9r_go_relaxed.owl	inhibition of embryonic pattern specification|negative regulation of ventral/lateral system|inhibition of ventral/lateral system|down regulation of embryonic pattern specification|down-regulation of embryonic pattern specification|down regulation of ventral/lateral system|downregulation of embryonic pattern specification|down-regulation of ventral/lateral system|downregulation of ventral/lateral system							mr	2014-04-03T15:25:20Z					biological_process											owl:Class	
GO:0009880	biolink:NamedThing	embryonic pattern specification	The process that results in the patterns of cell differentiation that will arise in an embryo.	tmpzr1t_l9r_go_relaxed.owl	embryonic pattern biosynthesis|ventral/lateral system|embryonic pattern formation													biological_process											owl:Class	
GO:1903537	biolink:NamedThing	meiotic cell cycle process involved in oocyte maturation	Any meiotic cell cycle process that is involved in oocyte maturation.	tmpzr1t_l9r_go_relaxed.owl	meiosis involved in oocyte maturation							pr	2014-10-09T10:46:14Z					biological_process											owl:Class	
GO:0001890	biolink:NamedThing	placenta development	The process whose specific outcome is the progression of the placenta over time, from its formation to the mature structure. The placenta is an organ of metabolic interchange between fetus and mother, partly of embryonic origin and partly of maternal origin.	tmpzr1t_l9r_go_relaxed.owl	placentation|placental development													biological_process											owl:Class	
GO:0110072	biolink:NamedThing	apical constriction involved in ventral furrow formation	The actin-mediated process that results in contraction of the apical end of a polarized columnar epithelial cell, contributing to formation of a ventral indentation (furrow) from the blastoderm epithelium, which is internalized to form a tube in the interior of the embryo, marking the start of gastrulation.	tmpzr1t_l9r_go_relaxed.owl								kmv	2017-12-06T17:04:49Z					biological_process											owl:Class	
GO:0061948	biolink:NamedThing	premature acrosome loss	The discharge, by sperm, of a single, anterior secretory granule before the sperm reaches to the zona pellucida of the oocyte. The process begins with the fusion of the outer acrosomal membrane with the sperm plasma membrane and ends with the exocytosis of the acrosomal contents.	tmpzr1t_l9r_go_relaxed.owl	spontaneous acrosome loss					If the release of the acrosome content when the sperm reaches to the zona pellucida, consider using acrosome reaction.		dph	2017-10-25T17:46:55Z					biological_process											owl:Class	
GO:0061141	biolink:NamedThing	lung ciliated cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a lung ciliated cell. A lung ciliated cell is a specialized lung epithelial cell that contains cilia for moving substances released from lung secretory cells.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-05-25T09:31:14Z					biological_process											owl:Class	
GO:0010844	biolink:NamedThing	recombination hotspot binding	Binding to a genomic region which promotes recombination.	tmpzr1t_l9r_go_relaxed.owl	DNA binding, recombination hotspot													molecular_function											owl:Class	
GO:0030904	biolink:NamedThing	retromer complex	A conserved hetero-pentameric membrane-associated complex involved in retrograde transport from endosomes to the Golgi apparatus. The budding yeast retromer comprises Vps35p, Vps29p, Vps26p, Vps5p, and Vps17p. The mammalian complex shows slight variation in composition compared to yeast, and comprises SNX1 or SNX2, SNX5 or SNX6, VPS26A or VPS26B, VPS29, and VPS35.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:1990000	biolink:NamedThing	amyloid fibril formation	The generation of amyloid fibrils, insoluble fibrous protein aggregates exhibiting beta sheet structure, from proteins.	tmpzr1t_l9r_go_relaxed.owl	amyloid structure assembly|amyloid structure formation|amyloid fibril assembly					Although deposition of amyloid fibrils is associated with diseases, e.g. Alzheimer's disease, amyloid formation is a normal process. Disease occurs when the balance between amyloid formation and clearance is disrupted (reviewed e.g. in PMID:29654159 and PMID:28937655). An example of a normal amyloid complex is composed of human RIP1 and RIP3 kinases  (PMID:22817896).		pr	2012-11-27T16:01:02Z					biological_process											owl:Class	
GO:0086038	biolink:NamedThing	calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Ca2+(in) + Na+(out) = Ca2+(out) + Na+(in), which contributes to regulating the membrane potential of a cardiac muscle cell.	tmpzr1t_l9r_go_relaxed.owl								tb	2011-11-11T03:33:44Z					molecular_function											owl:Class	
GO:0086036	biolink:NamedThing	regulation of cardiac muscle cell membrane potential	Any process that modulates the establishment or extent of a membrane potential in a cardiac muscle cell (a cardiomyocyte). A membrane potential is the electric potential existing across any membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane.	tmpzr1t_l9r_go_relaxed.owl								tb	2011-11-11T03:23:36Z					biological_process											owl:Class	
GO:1901214	biolink:NamedThing	regulation of neuron death	Any process that modulates the frequency, rate or extent of neuron death.	tmpzr1t_l9r_go_relaxed.owl	regulation of neuronal cell death|regulation of neuron cell death							rph	2012-08-02T09:57:41Z					biological_process											owl:Class	
GO:0001793	biolink:NamedThing	IgM receptor activity	Combining with an immunoglobulin of the IgM isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0098599	biolink:NamedThing	palmitoyl hydrolase activity	Catalysis of a hydrolase reaction that removes a palmitoyl moiety from some substrate.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-9027670|Reactome:R-HSA-5690046			dos	2014-04-11T17:57:36Z					molecular_function											owl:Class	
GO:0098734	biolink:NamedThing	macromolecule depalmitoylation	The removal of palymitoyl groups from a macromolecule.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0035171	biolink:NamedThing	lamellocyte differentiation	The process in which a relatively unspecialized hemocyte precursor cell acquires the specialized features of a lamellocyte. Lamellocytes are a hemocyte lineage that exists only in larvae, but are seldom observed in healthy animals. Lamellocytes differentiate massively in the lymph glands after parasitization and are large flat cells devoted to encapsulation of invaders too large to be phagocytosed by plasmatocytes.	tmpzr1t_l9r_go_relaxed.owl	lamellocyte cell differentiation													biological_process											owl:Class	
GO:0045627	biolink:NamedThing	positive regulation of T-helper 1 cell differentiation	Any process that activates or increases the frequency, rate or extent of T-helper 1 cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of T-helper 1 cell differentiation|activation of T-helper 1 cell differentiation|stimulation of T-helper 1 cell differentiation|positive regulation of T-helper 1 cell development|upregulation of T-helper 1 cell differentiation|up regulation of T-helper 1 cell differentiation					Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.								biological_process											owl:Class	
GO:0004174	biolink:NamedThing	electron-transferring-flavoprotein dehydrogenase activity	Catalysis of the reaction: a ubiquinone + reduced [electron-transfer flavoprotein] = a ubiquinol + H+ + oxidized [electron-transfer flavoprotein].	tmpzr1t_l9r_go_relaxed.owl	ETF:ubiquinone oxidoreductase activity|ETF-QO activity|electron transfer flavoprotein reductase activity|electron transfer flavoprotein dehydrogenase activity|electron transfer flavoprotein Q oxidoreductase activity|ETF dehydrogenase activity|electron-transferring-flavoprotein:ubiquinone oxidoreductase activity|ETF-ubiquinone oxidoreductase activity|electron transfer flavoprotein-ubiquinone oxidoreductase activity				MetaCyc:1.5.5.1-RXN|RHEA:24052|EC:1.5.5.1|Reactome:R-HSA-169270									molecular_function											owl:Class	
GO:0062227	biolink:NamedThing	positive regulation of adult somatic muscle development	Any process that increases the rate, frequency or extent of adult somatic muscle development.	tmpzr1t_l9r_go_relaxed.owl								dph	2020-03-16T13:29:41Z					biological_process											owl:Class	
GO:0003100	biolink:NamedThing	regulation of systemic arterial blood pressure by endothelin	The process in which endothelin modulates the force with which blood passes through the circulatory system. Endothelin is a hormone that is released by the endothelium, and it is a vasoconstrictor.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0090141	biolink:NamedThing	positive regulation of mitochondrial fission	Any process that increases the rate, frequency or extent of mitochondrial fission. Mitochondrial fission is the division of a mitochondrion within a cell to form two or more separate mitochondrial compartments.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of mitochondrial division							tb	2009-12-08T02:20:48Z					biological_process											owl:Class	
GO:0010896	biolink:NamedThing	regulation of triglyceride catabolic process	Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of triglyceride.	tmpzr1t_l9r_go_relaxed.owl	regulation of triacylglycerol catabolic process													biological_process											owl:Class	
GO:2000020	biolink:NamedThing	positive regulation of male gonad development	Any process that activates or increases the frequency, rate or extent of male gonad development.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of testicular development|positive regulation of testis development							jl	2010-07-15T03:29:13Z					biological_process											owl:Class	
GO:0008584	biolink:NamedThing	male gonad development	The process whose specific outcome is the progression of the male gonad over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl	testicular development|testis development													biological_process											owl:Class	
GO:0110070	biolink:NamedThing	cellularization cleavage furrow	A plasma membrane invagination at the site of separation of a multi-nucleate cell or syncytium into individual cells.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/14543|https://github.com/geneontology/go-ontology/issues/21737						kmv	2017-11-22T20:10:14Z					cellular_component											owl:Class	
GO:0080181	biolink:NamedThing	lateral root branching	Any process involved in the formation of branches in lateral roots.	tmpzr1t_l9r_go_relaxed.owl								dhl	2011-08-10T04:13:33Z					biological_process											owl:Class	
GO:0018993	biolink:NamedThing	somatic sex determination	The determination of sex and sexual phenotypes in an organism's soma.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0046551	biolink:NamedThing	retinal cone cell fate commitment	The process in which the developmental fate of a cell becomes restricted such that it will develop into a retinal cone cell. A retinal cone cell is one of the two photoreceptor subtypes in a camera-type eye.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0010807	biolink:NamedThing	regulation of synaptic vesicle priming	Any process that modulates the frequency, rate or extent of synaptic vesicle priming. Synaptic vesicle priming is the formation of SNARE-containing complexes, bringing synaptic vesicle membrane and plasma membranes into close proximity and thereby facilitating membrane fusion.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:2001236	biolink:NamedThing	regulation of extrinsic apoptotic signaling pathway	Any process that modulates the frequency, rate or extent of extrinsic apoptotic signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	regulation of extrinsic apoptotic signalling pathway|regulation of extrinsic apoptosis							pr	2011-11-24T01:30:05Z					biological_process											owl:Class	
GO:0097191	biolink:NamedThing	extrinsic apoptotic signaling pathway	A series of molecular signals in which a signal is conveyed from the cell surface to trigger the apoptotic death of a cell. The pathway starts with either a ligand binding to a cell surface receptor, or a ligand being withdrawn from a cell surface receptor (e.g. in the case of signaling by dependence receptors), and ends when the execution phase of apoptosis is triggered.	tmpzr1t_l9r_go_relaxed.owl	extrinsic apoptotic signaling pathway in presence of ligand|extrinsic apoptotic pathway|extrinsic apoptosis|death receptor-mediated apoptosis|extrinsic apoptotic signalling pathway					Fas acts as a death receptor with a role in apoptosis, but can also act as a non-apoptotic signal transducer.		pr	2011-11-23T09:34:28Z					biological_process											owl:Class	
GO:0120291	biolink:NamedThing	negative regulation of mitotic recombination involved in replication fork processing	Any process that inhibits or decreases the rate of mitotic DNA recombination during replication fork processing. Suppression of recombination at replication forks is necessary to prevent template switching.	tmpzr1t_l9r_go_relaxed.owl	suppression of template switching during replication fork processing|negative regulation of template switch recombination involved in replication fork processing|maintenance of template fidelity during replication fork processing							krc	2021-01-06T01:21:55Z					biological_process											owl:Class	
GO:0031297	biolink:NamedThing	replication fork processing	The process in which a DNA replication fork that has stalled is restored to a functional state and replication is restarted. The stalling may be due to DNA damage, DNA secondary structure, bound proteins, dNTP shortage, or other causes.	tmpzr1t_l9r_go_relaxed.owl	recovery from replication fork arrest|replication fork processing at rDNA locus|recovery from replication fork arrest at rDNA locus|replication fork restart|recovery from replication fork stalling at rDNA locus|collapsed replication fork processing|recovery from replication fork stalling|replication restart|replication fork processing at ribosomal DNA locus											GO:0034065		biological_process											owl:Class	
GO:1900395	biolink:NamedThing	negative regulation of kojic acid biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of kojic acid biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	down regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one synthesis|down regulation of C6H6O4 biosynthesis|inhibition of C6H6O4 biosynthetic process|inhibition of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one anabolism|negative regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one biosynthesis|down regulation of C6H6O4 synthesis|downregulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one formation|down-regulation of C6H6O4 biosynthesis|down-regulation of C6H6O4 formation|down-regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one formation|negative regulation of C6H6O4 biosynthesis|inhibition of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one synthesis|negative regulation of kojic acid anabolism|down-regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one anabolism|inhibition of kojic acid synthesis|downregulation of kojic acid formation|down regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one biosynthetic process|down regulation of kojic acid synthesis|down regulation of kojic acid anabolism|down-regulation of C6H6O4 synthesis|negative regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one synthesis|down regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one formation|downregulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one anabolism|negative regulation of kojic acid formation|downregulation of kojic acid biosynthetic process|downregulation of C6H6O4 biosynthetic process|inhibition of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one biosynthetic process|downregulation of C6H6O4 anabolism|negative regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one formation|negative regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one anabolism|negative regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one biosynthetic process|downregulation of C6H6O4 formation|downregulation of kojic acid synthesis|negative regulation of C6H6O4 biosynthetic process|down-regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one synthesis|downregulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one biosynthetic process|down regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one anabolism|inhibition of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one formation|inhibition of kojic acid formation|down-regulation of kojic acid synthesis|down-regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one biosynthesis|inhibition of kojic acid anabolism|down-regulation of kojic acid anabolism|down-regulation of C6H6O4 biosynthetic process|down regulation of kojic acid biosynthetic process|down regulation of C6H6O4 biosynthetic process|down regulation of C6H6O4 formation|negative regulation of C6H6O4 synthesis|down-regulation of C6H6O4 anabolism|downregulation of kojic acid biosynthesis|downregulation of C6H6O4 synthesis|downregulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one synthesis|inhibition of C6H6O4 biosynthesis|down regulation of kojic acid biosynthesis|inhibition of kojic acid biosynthesis|inhibition of C6H6O4 anabolism|inhibition of kojic acid biosynthetic process|inhibition of C6H6O4 formation|down regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one biosynthesis|negative regulation of C6H6O4 anabolism|down regulation of kojic acid formation|down regulation of C6H6O4 anabolism|inhibition of C6H6O4 synthesis|down-regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one biosynthetic process|down-regulation of kojic acid biosynthetic process|down-regulation of kojic acid biosynthesis|negative regulation of C6H6O4 formation|negative regulation of kojic acid biosynthesis|downregulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one biosynthesis|down-regulation of kojic acid formation|downregulation of C6H6O4 biosynthesis|downregulation of kojic acid anabolism|inhibition of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one biosynthesis|negative regulation of kojic acid synthesis							di	2012-04-18T04:20:03Z					biological_process											owl:Class	
GO:0005721	biolink:NamedThing	pericentric heterochromatin	Heterochromatin that is located adjacent to the CENP-A rich centromere 'central core' and characterized by methylated H3 histone at lysine 9 (H3K9me2/H3K9me3).	tmpzr1t_l9r_go_relaxed.owl	centric heterochromatin|nuclear cluster|nuclear centric heterochromatin|centromeric heterochromatin|nuclear pericentric heterochromatin											GO:0002137|GO:0031618		cellular_component											owl:Class	
GO:0033105	biolink:NamedThing	chlorosome envelope	The structure, composed of a monolayer of glycolipids with embedded proteins, that encloses the pigments and other contents of the chlorosome.	tmpzr1t_l9r_go_relaxed.owl	chlorosome membrane					Note that the chlorosome envelope is not a single or double lipid bilayer, so this term is not a child of 'organelle membrane ; GO:0031090' or 'organelle envelope ; GO:0031967'.								cellular_component											owl:Class	
GO:0046858	biolink:NamedThing	chlorosome	A large enclosure of aggregated pigment, typically bacteriochlorophyll c (BChl c), that acts as a light-harvesting antenna structure and is characteristic of green photosynthetic bacteria (e.g. Chlorobiaceae). The BChl aggregates are organized into lamellar elements by pigment-pigment rather than pigment-protein interactions. Chlorosomes also contain BChl a, carotenoids, quinones, lipids, and proteins, and are attached to the cytoplasmic membrane via a BChl a-containing protein baseplate.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Chlorosome									cellular_component											owl:Class	
GO:1990262	biolink:NamedThing	anti-Mullerian hormone signaling pathway	A series of molecular signals initiated by the binding of anti-Mullerian hormone to its receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.	tmpzr1t_l9r_go_relaxed.owl						An example of this is Amhr2 in M. musculus (Q8K592) a receptor for anti-mullerian hormone, described in PMID:23624077.		hjd	2014-01-08T20:42:09Z					biological_process											owl:Class	
GO:0060926	biolink:NamedThing	cardiac pacemaker cell development	The process whose specific outcome is the progression of a pacemaker cell over time, from its formation to the mature state. Pacemaker cells are specialized cardiomyocytes that are responsible for regulating the timing of heart contractions.	tmpzr1t_l9r_go_relaxed.owl	pacemaker cell development							dph	2009-09-29T11:51:55Z					biological_process											owl:Class	
GO:0044558	biolink:NamedThing	uterine smooth muscle relaxation	A process in which the extent of smooth muscle contraction is reduced in the uterus.	tmpzr1t_l9r_go_relaxed.owl	smooth muscle relaxation of the uterus							jl	2012-04-05T02:57:11Z					biological_process											owl:Class	
GO:0110037	biolink:NamedThing	regulation of nematode male tail tip morphogenesis	Any process that modulates the frequency, rate or extent of nematode male tail tip morphogenesis, the process in which the anatomical structure of the adult male tail tip is generated and organized.	tmpzr1t_l9r_go_relaxed.owl								kmv	2017-07-24T20:21:34Z					biological_process											owl:Class	
GO:0051457	biolink:NamedThing	maintenance of protein location in nucleus	Any process in which a protein is maintained in the nucleus and prevented from moving elsewhere. These include sequestration within the nucleus, protein stabilization to prevent transport elsewhere and the active retrieval of proteins that escape the nucleus.	tmpzr1t_l9r_go_relaxed.owl	sequestration of protein in nucleus|storage of protein in nucleus|protein retention in nucleus|nuclear protein sequestration|protein sequestration in nucleus|maintenance of protein location in cell nucleus|nuclear protein retention|protein-nuclear retention|maintenance of protein localization in nucleus|protein storage in nucleus|maintenance of nuclear protein localization|nuclear protein sequestering													biological_process											owl:Class	
GO:0090561	biolink:NamedThing	nuclear migration during mitotic telophase	The dynein-driven microtubule based nuclear migration, whereby daughter nuclei are positioned away from the cell division site prior to cytokinesis.	tmpzr1t_l9r_go_relaxed.owl								tb	2014-03-27T15:17:10Z					biological_process											owl:Class	
GO:0007483	biolink:NamedThing	genital disc morphogenesis	The process in which the anatomical structures derived from the genital disc are generated and organized. This includes the transformation of a genital imaginal disc from a monolayered epithelium in the larvae of holometabolous insects into the recognizable adult genital structures, the anal plates and the hind gut.	tmpzr1t_l9r_go_relaxed.owl	genital disc metamorphosis													biological_process											owl:Class	
GO:1904706	biolink:NamedThing	negative regulation of vascular associated smooth muscle cell proliferation	Any process that stops, prevents or reduces the frequency, rate or extent of vascular smooth muscle cell proliferation.	tmpzr1t_l9r_go_relaxed.owl	downregulation of VSMC proliferation|down-regulation of VSMC proliferation|down-regulation of vascular smooth muscle cell proliferation|downregulation of vascular smooth muscle cell proliferation|negative regulation of vascular smooth muscle cell proliferation|inhibition of VSMC proliferation|down regulation of vascular smooth muscle cell proliferation|negative regulation of VSMC proliferation|down regulation of VSMC proliferation|inhibition of vascular smooth muscle cell proliferation							sl	2015-10-01T16:05:26Z					biological_process											owl:Class	
GO:0046320	biolink:NamedThing	regulation of fatty acid oxidation	Any process that modulates the frequency, rate or extent of fatty acid oxidation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0060829	biolink:NamedThing	negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation	Any process that decreases the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin in the anterior end of the neural plate. This regulation sets up a Wnt signaling gradient along the anterior/posterior axis.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of canonical Wnt-activated signaling pathway involved in neural plate anterior/posterior pattern|negative regulation of Wnt receptor signaling pathway through beta-catenin involved in neural plate anterior/posterior pattern formation|negative regulation of canonical Wnt receptor signaling pathway involved in neural plate anterior/posterior pattern|negative regulation of canonical Wnt receptor signalling pathway involved in neural plate anterior/posterior pattern formation							dph	2009-08-11T01:58:33Z					biological_process											owl:Class	
GO:1902217	biolink:NamedThing	erythrocyte apoptotic process	Any apoptotic process in an erythrocyte.	tmpzr1t_l9r_go_relaxed.owl	RBC apoptotic process|RBC apoptosis|red blood cell apoptotic process|erythrocyte apoptosis|red blood cell apoptosis							rl	2013-06-13T10:02:29Z					biological_process											owl:Class	
GO:0062107	biolink:NamedThing	regulation of protein localization to non-growing cell tip	Any process that modulates the frequency, rate or extent of protein localization to a non-growing cell tip.	tmpzr1t_l9r_go_relaxed.owl								dph	2019-02-05T12:59:18Z					biological_process											owl:Class	
GO:1902487	biolink:NamedThing	protein localization to non-growing cell tip	A process in which a protein is transported to, or maintained in, a location within a non-growing cell tip.	tmpzr1t_l9r_go_relaxed.owl	protein localization in non-growing cell tip|protein localisation to non-growing cell tip|protein localisation in non-growing cell tip							mah	2013-11-12T16:38:22Z					biological_process											owl:Class	
GO:1905690	biolink:NamedThing	nucleus disassembly	The disaggregation of a nucleus into its constituent components.	tmpzr1t_l9r_go_relaxed.owl	cell nucleus disassembly							pr	2016-11-14T13:38:57Z					biological_process											owl:Class	
GO:0072167	biolink:NamedThing	specification of mesonephric tubule identity	The process in which the tubules of the mesonephros acquire their identity.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-02-26T01:51:03Z					biological_process											owl:Class	
GO:0097186	biolink:NamedThing	amelogenesis	The process whose specific outcome is the formation of tooth enamel, occurring in two stages: secretory stage and maturation stage.	tmpzr1t_l9r_go_relaxed.owl	enamel development							pr	2011-11-21T09:01:24Z					biological_process											owl:Class	
GO:0016519	biolink:NamedThing	gastric inhibitory peptide receptor activity	Combining with gastric inhibitory peptide (GIP) and transmitting the signal across the membrane to activate an associated G-protein.	tmpzr1t_l9r_go_relaxed.owl	GIP receptor activity|glucose-dependent insulinotropic polypeptide receptor activity													molecular_function											owl:Class	
GO:0098035	biolink:NamedThing	viral DNA genome packaging via site-specific sequence recognition	The encapsulation of the viral DNA genome within the capsid, which proceeds via cleavage of the viral DNA at specific sites by a viral terminase.	tmpzr1t_l9r_go_relaxed.owl								bm	2012-07-20T11:36:49Z					biological_process											owl:Class	
GO:0002341	biolink:NamedThing	central B cell anergy	Any process contributing to anergy, a state of functional inactivation that occurs as part of tolerance induction, in B cells in the bone marrow.	tmpzr1t_l9r_go_relaxed.owl	central B-cell anergy|central B-lymphocyte anergy|central B lymphocyte anergy													biological_process											owl:Class	
GO:0120020	biolink:NamedThing	cholesterol transfer activity	Removes cholesterol from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle.	tmpzr1t_l9r_go_relaxed.owl	cholesterol transporter activity|cholesterol carrier activity|intermembrane cholesterol transfer activity	https://github.com/geneontology/go-ontology/issues/12329			Reactome:R-HSA-265443|Reactome:R-HSA-1454928|Reactome:R-HSA-5682111|Reactome:R-HSA-8951850|Reactome:R-HSA-265545|Reactome:R-HSA-266082|Reactome:R-HSA-216723			krc	2017-03-17T04:46:12Z			GO:0017127		molecular_function											owl:Class	
GO:0005977	biolink:NamedThing	glycogen metabolic process	The chemical reactions and pathways involving glycogen, a polydisperse, highly branched glucan composed of chains of D-glucose residues in alpha-(1->4) glycosidic linkage, joined together by alpha-(1->6) glycosidic linkages.	tmpzr1t_l9r_go_relaxed.owl	glycogen metabolism													biological_process											owl:Class	
GO:0046673	biolink:NamedThing	negative regulation of compound eye retinal cell programmed cell death	Any process that stops, prevents, or reduces the frequency, rate or extent of programmed cell death that occurs in the compound eye retina.	tmpzr1t_l9r_go_relaxed.owl	inhibition of retinal cell programmed cell death|negative regulation of retinal cell programmed cell death|down-regulation of retinal cell programmed cell death|negative regulation of retina cell programmed cell death|downregulation of retinal cell programmed cell death|down regulation of retinal cell programmed cell death													biological_process											owl:Class	
GO:0046667	biolink:NamedThing	compound eye retinal cell programmed cell death	Programmed cell death that occurs in the retina to remove excess cells between ommatidia, thus resulting in a hexagonal lattice, precise with respect to cell number and position surrounding each ommatidium.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1903021	biolink:NamedThing	regulation of phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands	Any process that modulates the frequency, rate or extent of phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands.	tmpzr1t_l9r_go_relaxed.owl								tb	2014-05-14T23:44:35Z					biological_process											owl:Class	
GO:0090580	biolink:NamedThing	phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands	Catalysis of the hydrolytic removal of phosphoglycolate from the 3'-terminus of a 3'-phosphoglycolate-terminated DNA strand.	tmpzr1t_l9r_go_relaxed.owl								tb	2014-05-14T15:52:41Z					molecular_function											owl:Class	
GO:0061330	biolink:NamedThing	Malpighian tubule stellate cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a Malpighian tubule stellate cell. A Malpighian tubule stellate cell is a specialized epithelial secretory cell that moves chloride ions and water across the tubule epithelium.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-09-28T01:32:55Z					biological_process											owl:Class	
GO:1900047	biolink:NamedThing	negative regulation of hemostasis	Any process that stops, prevents or reduces the frequency, rate or extent of hemostasis.	tmpzr1t_l9r_go_relaxed.owl	downregulation of hemostasis|down-regulation of hemostasis|down regulation of hemostasis|inhibition of hemostasis							jl	2012-01-19T03:23:42Z					biological_process											owl:Class	
GO:0072043	biolink:NamedThing	regulation of pre-tubular aggregate formation by cell-cell signaling	Any process that mediates the transfer of information from one cell to another that modulates the rate, frequency, or extent of pre-tubular aggregate formation. Pre-tubular aggregate formation is the cell adhesion process in which mesenchymal cells adhere to one another in the initial stages of the formation of the pre-tubular aggregate, the earliest recognizable structure of the kidney.	tmpzr1t_l9r_go_relaxed.owl	regulation of pre-tubular aggregate formation by cell-cell signalling							mah	2010-01-25T03:12:03Z					biological_process											owl:Class	
GO:0070859	biolink:NamedThing	positive regulation of bile acid biosynthetic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of bile acids.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of bile acid biosynthetic process|positive regulation of bile acid anabolism|positive regulation of bile acid synthesis|activation of bile acid biosynthetic process|up regulation of bile acid biosynthetic process|upregulation of bile acid biosynthetic process|positive regulation of bile acid biosynthesis|positive regulation of bile acid formation|stimulation of bile acid biosynthetic process							mah	2009-08-14T03:22:58Z					biological_process											owl:Class	
GO:0006699	biolink:NamedThing	bile acid biosynthetic process	The chemical reactions and pathways resulting in the formation of bile acids, any of a group of steroid carboxylic acids occurring in bile.	tmpzr1t_l9r_go_relaxed.owl	bile acid biosynthesis|bile acid formation|bile acid anabolism|bile acid synthesis													biological_process											owl:Class	
GO:0048385	biolink:NamedThing	regulation of retinoic acid receptor signaling pathway	Any process that modulates the frequency, rate or extent of retinoic acid receptor signaling pathway activity.	tmpzr1t_l9r_go_relaxed.owl	regulation of RAR signaling pathway|regulation of retinoic acid receptor signalling pathway													biological_process											owl:Class	
GO:0060014	biolink:NamedThing	granulosa cell differentiation	The process in which a relatively unspecialized cell acquires the specialized features of a granulosa cell, a supporting cell for the developing female gamete in the ovary of mammals.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0001731	biolink:NamedThing	formation of translation preinitiation complex	The joining of the small ribosomal subunit, ternary complex, and mRNA.	tmpzr1t_l9r_go_relaxed.owl	translation preinitiation complex assembly|formation of translation pre-initiation complex					See also the cellular component terms 'eukaryotic 43S preinitiation complex ; GO:0016282', 'eukaryotic 48S initiation complex ; GO:0033290', and their children.								biological_process											owl:Class	
GO:0034746	biolink:NamedThing	APC-IQGAP1-CLIP-170 complex	A protein complex that contains the tumor suppressor protein adenomatous polyposis coli (APC), the small GTPase Cdc42, and CLIP-170; may play a role in cytoskeleton organization and cell migration.	tmpzr1t_l9r_go_relaxed.owl						Note that the gene/protein name 'APC' should not be confused with the abbreviation for 'anaphase promoting complex'.								cellular_component											owl:Class	
GO:0003383	biolink:NamedThing	apical constriction	The actin-mediated process that results in the contraction of the apical end of a polarized columnar epithelial cell.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-12-09T07:30:34Z					biological_process											owl:Class	
GO:0003382	biolink:NamedThing	epithelial cell morphogenesis	The change in form that occurs when an epithelial cell progresses from its initial formation to its mature state.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-12-09T07:21:06Z					biological_process											owl:Class	
GO:0002430	biolink:NamedThing	complement receptor mediated signaling pathway	A series of molecular signals generated as a consequence of a component of the complement pathway binding to a complement receptor. Such components include both whole complement proteins and fragments of complement proteins generated through the activity of the complement pathway.	tmpzr1t_l9r_go_relaxed.owl	complement receptor mediated signalling pathway|immune response-regulating cell surface receptor signalling pathway													biological_process											owl:Class	
GO:0030353	biolink:NamedThing	fibroblast growth factor receptor antagonist activity	Interacts with the fibroblast growth factor receptor to reduce the action of another ligand, the agonist.	tmpzr1t_l9r_go_relaxed.owl	FGF receptor antagonist activity|FGFR antagonist activity													molecular_function											owl:Class	
GO:1901834	biolink:NamedThing	regulation of deadenylation-independent decapping of nuclear-transcribed mRNA	Any process that modulates the frequency, rate or extent of deadenylation-independent decapping of nuclear-transcribed mRNA.	tmpzr1t_l9r_go_relaxed.owl	regulation of deadenylation-independent decapping of nuclear mRNA|regulation of deadenylylation-independent decapping							al	2013-01-22T22:42:17Z					biological_process											owl:Class	
GO:0002232	biolink:NamedThing	leukocyte chemotaxis involved in inflammatory response	The movement of an immune cell in response to an external stimulus contributing to an inflammatory response.	tmpzr1t_l9r_go_relaxed.owl	leucocyte chemotaxis during inflammatory response|immune cell chemotaxis during inflammatory response|leukocyte chemotaxis during inflammatory response													biological_process											owl:Class	
GO:0048286	biolink:NamedThing	lung alveolus development	The process whose specific outcome is the progression of the alveolus over time, from its formation to the mature structure. The alveolus is a sac for holding air in the lungs; formed by the terminal dilation of air passageways.	tmpzr1t_l9r_go_relaxed.owl	alveolarization|alveologenesis													biological_process											owl:Class	
GO:0071710	biolink:NamedThing	membrane macromolecule biosynthetic process	The chemical reactions and pathways resulting in the formation of a macromolecule destined to form part of a membrane in a cell.	tmpzr1t_l9r_go_relaxed.owl	membrane macromolecule synthesis|membrane macromolecule formation|membrane macromolecule anabolism|membrane macromolecule biosynthesis							mah	2010-03-10T11:29:52Z					biological_process											owl:Class	
GO:1990915	biolink:NamedThing	structural constituent of ascospore wall	The action of a molecule that contributes to the structural integrity of an ascospore wall.	tmpzr1t_l9r_go_relaxed.owl								al	2015-12-09T19:04:53Z					molecular_function											owl:Class	
GO:0046411	biolink:NamedThing	2-keto-3-deoxygluconate transmembrane transport	The process in which 2-keto-3-deoxygluconate is transported across a lipid bilayer, from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	2-keto-3-deoxygluconate transport													biological_process											owl:Class	
GO:0021941	biolink:NamedThing	negative regulation of cerebellar granule cell precursor proliferation	The process that stops, prevents or reduces the rate or extent of granule cell precursor proliferation.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of granule cell precursor proliferation|down regulation of granule cell precursor proliferation|downregulation of granule cell precursor proliferation|inhibition of granule cell precursor proliferation													biological_process											owl:Class	
GO:0002657	biolink:NamedThing	positive regulation of tolerance induction to nonself antigen	Any process that activates or increases the frequency, rate, or extent of tolerance induction to nonself antigen.	tmpzr1t_l9r_go_relaxed.owl	upregulation of tolerance induction to nonself antigen|up-regulation of tolerance induction to nonself antigen|stimulation of tolerance induction to nonself antigen|up regulation of tolerance induction to nonself antigen|activation of tolerance induction to nonself antigen													biological_process											owl:Class	
GO:1901251	biolink:NamedThing	positive regulation of lung goblet cell differentiation	Any process that activates or increases the frequency, rate or extent of lung goblet cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	activation of lung goblet cell differentiation|up regulation of pulmonary goblet cell differentiation|up-regulation of lung goblet cell differentiation|up regulation of lung goblet cell differentiation|upregulation of lung goblet cell differentiation|activation of pulmonary goblet cell differentiation|upregulation of pulmonary goblet cell differentiation|up-regulation of pulmonary goblet cell differentiation|positive regulation of pulmonary goblet cell differentiation							vk	2012-08-08T08:59:44Z					biological_process											owl:Class	
GO:0004222	biolink:NamedThing	metalloendopeptidase activity	Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.	tmpzr1t_l9r_go_relaxed.owl	metalloendoproteinase activity|metalloendoprotease activity				Reactome:R-HSA-194800|Reactome:R-HSA-5333671|Reactome:R-HSA-2168982|Reactome:R-HSA-2514790|Reactome:R-HSA-2473594|Reactome:R-HSA-181567|Reactome:R-HSA-8940561|Reactome:R-HSA-194809|Reactome:R-HSA-8943959|Reactome:R-HSA-1454822|Reactome:R-HSA-8874192|Reactome:R-HSA-3827958|Reactome:R-HSA-4086205|Reactome:R-HSA-2473584|Reactome:R-HSA-1564142|Reactome:R-HSA-2168046|Reactome:R-HSA-8876868|Reactome:R-HSA-8874201|Reactome:R-HSA-8942302|Reactome:R-HSA-1474196|Reactome:R-HSA-8874187|Reactome:R-HSA-2002440|Reactome:R-HSA-194793|Reactome:R-HSA-381435|Reactome:R-HSA-2002428|Reactome:R-HSA-5694082|Reactome:R-HSA-264758|Reactome:R-HSA-2534240|Reactome:R-HSA-5250892|Reactome:R-HSA-5250978|Reactome:R-HSA-1564120|Reactome:R-HSA-8940959|Reactome:R-HSA-2485148|Reactome:R-HSA-4224014|Reactome:R-HSA-1655851|Reactome:R-HSA-1454757|Reactome:R-HSA-1251992|Reactome:R-HSA-8949649|Reactome:R-HSA-6784620|Reactome:R-HSA-2022141|Reactome:R-HSA-1564143|Reactome:R-HSA-3371385|Reactome:R-HSA-1299476|Reactome:R-HSA-381518|Reactome:R-HSA-1299478|Reactome:R-HSA-420818|Reactome:R-HSA-8940554|Reactome:R-HSA-8940641|Reactome:R-HSA-5228578|Reactome:R-HSA-1564184|Reactome:R-HSA-2533874|Reactome:R-HSA-8867344|Reactome:R-HSA-1474210|Reactome:R-HSA-3791149|Reactome:R-HSA-9624272|Reactome:R-HSA-3791295|Reactome:R-HSA-5250606|Reactome:R-HSA-8874194|Reactome:R-HSA-3788075|Reactome:R-HSA-8949659|Reactome:R-HSA-194808|Reactome:R-HSA-2533944|Reactome:R-HSA-5362793|Reactome:R-HSA-1564112|EC:3.4.24.-|Reactome:R-HSA-2473596|Reactome:R-HSA-5250962|Reactome:R-HSA-2537499|Reactome:R-HSA-3791155|Reactome:R-HSA-2484882|Reactome:R-HSA-1458433|Reactome:R-HSA-1564179|Reactome:R-HSA-1564164|Reactome:R-HSA-381537|Reactome:R-HSA-2534248|Reactome:R-HSA-2485111|Reactome:R-HSA-3828025|Reactome:R-HSA-2533970|Reactome:R-HSA-194818|Reactome:R-HSA-1474213|Reactome:R-HSA-8874195|Reactome:R-HSA-3791319|Reactome:R-HSA-2533950|Reactome:R-HSA-2514831|Reactome:R-HSA-1168777|Reactome:R-HSA-1564117|Reactome:R-HSA-2179402|Reactome:R-HSA-177946|Reactome:R-HSA-2533965|Reactome:R-HSA-8877620|Reactome:R-HSA-194796|Reactome:R-HSA-8949668|Reactome:R-HSA-1564169|Reactome:R-HSA-1592310									molecular_function											owl:Class	
GO:0038145	biolink:NamedThing	macrophage colony-stimulating factor signaling pathway	A series of molecular signals initiated by the binding of the cytokine macrophage colony-stimulating factor (M-CSF) to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.	tmpzr1t_l9r_go_relaxed.owl	macrophage colony-stimulating factor signalling pathway|M-CSF signaling pathway							bf	2012-04-27T11:04:18Z					biological_process											owl:Class	
GO:0051464	biolink:NamedThing	positive regulation of cortisol secretion	Any process that activates or increases the frequency, rate or extent of the regulated release of cortisol from a cell.	tmpzr1t_l9r_go_relaxed.owl	activation of cortisol secretion|upregulation of cortisol secretion|up-regulation of cortisol secretion|up regulation of cortisol secretion|stimulation of cortisol secretion													biological_process											owl:Class	
GO:0042116	biolink:NamedThing	macrophage activation	A change in morphology and behavior of a macrophage resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor.	tmpzr1t_l9r_go_relaxed.owl	macrophage polarization													biological_process											owl:Class	
GO:0071887	biolink:NamedThing	leukocyte apoptotic process	Any apoptotic process in a leukocyte, an achromatic cell of the myeloid or lymphoid lineages capable of ameboid movement, found in blood or other tissue.	tmpzr1t_l9r_go_relaxed.owl	leukocyte apoptosis					Note that a lymphocyte is a cell of the B cell, T cell, or natural killer cell lineage (CL:0000542).		mah	2010-09-14T12:44:09Z					biological_process											owl:Class	
GO:0010694	biolink:NamedThing	positive regulation of alkaline phosphatase activity	Any process that increases the frequency, rate or extent of alkaline phosphatase activity, the catalysis of the reaction: an orthophosphoric monoester + H2O = an alcohol + phosphate, with an alkaline pH optimum.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0004035	biolink:NamedThing	alkaline phosphatase activity	Catalysis of the reaction: an orthophosphoric monoester + H2O = an alcohol + phosphate, with an alkaline pH optimum.	tmpzr1t_l9r_go_relaxed.owl	glycerophosphatase activity|alkaline phosphohydrolase activity|phosphate-monoester phosphohydrolase (alkaline optimum)|orthophosphoric-monoester phosphohydrolase (alkaline optimum)|phosphomonoesterase activity|alkaline phenyl phosphatase activity|alkaline phosphomonoesterase activity				EC:3.1.3.1|Reactome:R-HSA-8878787|MetaCyc:ALKAPHOSPHA-RXN									molecular_function											owl:Class	
GO:0015887	biolink:NamedThing	pantothenate transmembrane transport	The process in which pantothenate is transported across a membrane. Pantothenate is the anion of pantothenic acid, the amide of beta-alanine and pantoic acid; it is a B complex vitamin that is a constituent of coenzyme A and is distributed ubiquitously in foods.	tmpzr1t_l9r_go_relaxed.owl	vitamin B5 transport|pantothenate membrane transport|pantothenate transport					Note that this term is not intended for use in annotating lateral movement within membranes.								biological_process											owl:Class	
GO:0043944	biolink:NamedThing	negative regulation of asexual sporulation resulting in formation of a cellular spore	Any process that stops, prevents, or reduces the frequency, rate or extent of the formation of a cellular spore derived from the products of mitosis.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0000742	biolink:NamedThing	karyogamy involved in conjugation with cellular fusion	During sexual reproduction, the creation of a single nucleus from multiple nuclei as a result of fusing the lipid bilayers that surround each nuclei. This occurs after cytogamy.	tmpzr1t_l9r_go_relaxed.owl	karyogamy during conjugation with cellular fusion													biological_process											owl:Class	
GO:0006277	biolink:NamedThing	DNA amplification	The process in which the number of copies of a gene is increased in certain cells as extra copies of DNA are made in response to certain signals of cell development or of stress from the environment.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0051455	biolink:NamedThing	monopolar spindle attachment to meiosis I kinetochore	The process in which spindle microtubules become physically associated with the proteins making up the kinetochore complex during meiosis I. During meiosis I sister kinetochores are lying next to each other facing the same spindle pole and monopolar attachment of the chromatid to the spindle occurs.	tmpzr1t_l9r_go_relaxed.owl	monopolar attachment|attachment of spindle microtubules to kinetochore involved in homologous chromosome segregation|attachment of spindle microtubules to kinetochore during meiosis I|attachment of spindle microtubules to kinetochore involved in meiosis I|sister kinetochore mono-orientation					Note that the synonym 'monopolar attachment' refers to the normal attachment of sister chromosomes to the spindle in meiosis I, and not to the aberrant attachment of sister kinetochores to a single pole in mitosis.								biological_process											owl:Class	
GO:0030251	biolink:NamedThing	guanylate cyclase inhibitor activity	Stops, prevents or reduces the activity of guanylate cyclase.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:2000922	biolink:NamedThing	negative regulation of arabinoxylan-containing compound catabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of arabinoxylan-containing compound catabolic process.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of arabinoxylan catabolism							tt	2011-08-01T12:39:00Z					biological_process											owl:Class	
GO:0021657	biolink:NamedThing	rhombomere 2 formation	The process that gives rise to rhombomere 2. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0016013	biolink:NamedThing	syntrophin complex	A protein complex that includes alpha-, beta1-, beta2-syntrophins and syntrophin-like proteins; the syntrophin complex binds to the second half of the carboxy-terminal domain of dystrophin; also associates with neuronal nitric oxide synthase.	tmpzr1t_l9r_go_relaxed.owl	nitric oxide synthase-dystrophin complex, skeletal muscle													cellular_component											owl:Class	
GO:0016010	biolink:NamedThing	dystrophin-associated glycoprotein complex	A multiprotein complex that forms a strong mechanical link between the cytoskeleton and extracellular matrix; typical of, but not confined to, muscle cells. The complex is composed of transmembrane, cytoplasmic, and extracellular proteins, including dystrophin, sarcoglycans, dystroglycan, dystrobrevins, syntrophins, sarcospan, caveolin-3, and NO synthase.	tmpzr1t_l9r_go_relaxed.owl	dystrophin glycoprotein complex|DGC													cellular_component											owl:Class	
GO:0099564	biolink:NamedThing	modification of synaptic structure, modulating synaptic transmission	Any process that modulates synaptic transmission via modification of the structure of the synapse.	tmpzr1t_l9r_go_relaxed.owl						Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.								biological_process											owl:Class	
GO:0030686	biolink:NamedThing	90S preribosome	A large ribonucleoprotein complex considered to be the earliest preribosomal complex. In S. cerevisiae, it has a size of 90S and consists of the 35S pre-rRNA, early-associating ribosomal proteins most of which are part of the small ribosomal subunit, the U3 snoRNA and associated proteins.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:1905124	biolink:NamedThing	negative regulation of glucosylceramidase activity	Any process that stops, prevents or reduces the frequency, rate or extent of glucosylceramidase activity.	tmpzr1t_l9r_go_relaxed.owl	inhibition of glucosphingosine glucosylhydrolase activity|downregulation of glucosphingosine glucosylhydrolase activity|down regulation of acid beta-glucosidase activity|downregulation of acid beta-glucosidase activity|negative regulation of beta-glucosylceramidase activity|down regulation of glucosphingosine glucosylhydrolase activity|inhibition of glucosylceramidase activity|downregulation of beta-glucocerebrosidase activity|inhibition of beta-D-glucocerebrosidase activity|down-regulation of glucosylsphingosine beta-D-glucosidase activity|down regulation of glucosylcerebrosidase activity|down-regulation of glucosphingosine glucosylhydrolase activity|negative regulation of glucosylcerebrosidase activity|downregulation of ceramide glucosidase activity|negative regulation of ceramide glucosidase activity|down-regulation of glucosylceramidase activity|downregulation of beta-D-glucocerebrosidase activity|downregulation of GlcCer-beta-glucosidase activity|down regulation of GlcCer-beta-glucosidase activity|inhibition of acid beta-glucosidase activity|downregulation of beta-glucosylceramidase activity|down-regulation of psychosine hydrolase activity|negative regulation of glucocerebrosidase activity|inhibition of beta-glucosylceramidase activity|down regulation of beta-D-glucocerebrosidase activity|down-regulation of glucocerebrosidase activity|down regulation of glucosylsphingosine beta-D-glucosidase activity|negative regulation of D-glucosyl-N-acylsphingosine glucohydrolase activity|downregulation of glucosylcerebrosidase activity|negative regulation of glucosylsphingosine beta-glucosidase activity|inhibition of glucosylcerebrosidase activity|inhibition of ceramide glucosidase activity|negative regulation of beta-D-glucocerebrosidase activity|down regulation of beta-glucocerebrosidase activity|negative regulation of acid beta-glucosidase activity|inhibition of psychosine hydrolase activity|down-regulation of glucosylcerebrosidase activity|down regulation of glucosylsphingosine beta-glucosidase activity|downregulation of glucosylceramidase activity|negative regulation of beta-glucocerebrosidase activity|down-regulation of GlcCer-beta-glucosidase activity|inhibition of beta-glucocerebrosidase activity|downregulation of glucosylsphingosine beta-glucosidase activity|downregulation of glucosylsphingosine beta-D-glucosidase activity|down-regulation of ceramide glucosidase activity|downregulation of glucocerebrosidase activity|negative regulation of glucosphingosine glucosylhydrolase activity|down regulation of glucocerebrosidase activity|down-regulation of D-glucosyl-N-acylsphingosine glucohydrolase activity|inhibition of D-glucosyl-N-acylsphingosine glucohydrolase activity|negative regulation of glucosylsphingosine beta-D-glucosidase activity|downregulation of psychosine hydrolase activity|down-regulation of beta-glucosylceramidase activity|down-regulation of beta-glucocerebrosidase activity|down regulation of D-glucosyl-N-acylsphingosine glucohydrolase activity|down regulation of glucosylceramidase activity|downregulation of D-glucosyl-N-acylsphingosine glucohydrolase activity|inhibition of GlcCer-beta-glucosidase activity|down-regulation of glucosylsphingosine beta-glucosidase activity|down regulation of psychosine hydrolase activity|negative regulation of GlcCer-beta-glucosidase activity|down-regulation of beta-D-glucocerebrosidase activity|negative regulation of GCase activity|inhibition of glucocerebrosidase activity|down regulation of ceramide glucosidase activity|inhibition of glucosylsphingosine beta-D-glucosidase activity|inhibition of glucosylsphingosine beta-glucosidase activity|negative regulation of psychosine hydrolase activity|down-regulation of acid beta-glucosidase activity|down regulation of beta-glucosylceramidase activity							bf	2016-04-11T15:44:35Z					biological_process											owl:Class	
GO:0004348	biolink:NamedThing	glucosylceramidase activity	Catalysis of the reaction: D-glucosyl-N-acylsphingosine + H2O = D-glucose + N-acylsphingosine.	tmpzr1t_l9r_go_relaxed.owl	GlcCer-beta-glucosidase activity|D-glucosyl-N-acylsphingosine glucohydrolase activity|psychosine hydrolase activity|glucosylsphingosine beta-glucosidase activity|glucosylsphingosine beta-D-glucosidase activity|glucosphingosine glucosylhydrolase activity|beta-glucosylceramidase activity|beta-D-glucocerebrosidase activity|acid beta-glucosidase activity|beta-glucocerebrosidase activity|ceramide glucosidase activity|glucosylcerebrosidase activity|glucocerebrosidase activity				Reactome:R-HSA-1861789|EC:3.2.1.45|Reactome:R-HSA-1861788|RHEA:13269|MetaCyc:GLUCOSYLCERAMIDASE-RXN|Reactome:R-HSA-1605591									molecular_function											owl:Class	
GO:0001147	biolink:NamedThing	transcription termination site sequence-specific DNA binding	Binding to a sequence of DNA that promotes termination by RNA polymerase. The transcribed region might be described as a gene, cistron, or operon.	tmpzr1t_l9r_go_relaxed.owl	mitochondrial RNA polymerase terminator site sequence-specific DNA binding transcription factor activity|bacterial-type RNA polymerase termination site sequence-specific DNA binding|transcription termination site DNA binding|transcription factor activity, mitochondrial RNA polymerase terminator site sequence-specific binding|mitochondrial RNA polymerase termination site sequence-specific DNA binding					Transcription termination sites can be recognized by the RNA polymerase (RNAP) itself or by another protein which interacts with the RNAP to promote transcription termination. Note that not all genes have a DNA specific sequence that functions as a termination site; for most mRNAs transcribed by RNAP II termination is not mediated by a specific termination sequence, but is coupled to polyadenylation.		krc	2011-01-27T02:42:23Z			GO:0001145|GO:0001148|GO:0001160|GO:0001146		molecular_function											owl:Class	
GO:0039670	biolink:NamedThing	viral capsid, turret	A turret-like appendage formed at the vertices of an icosahedral capsid.	tmpzr1t_l9r_go_relaxed.owl								bf	2013-09-25T10:08:14Z					cellular_component											owl:Class	
GO:0010304	biolink:NamedThing	PSII associated light-harvesting complex II catabolic process	The chemical reactions and pathways resulting in the breakdown of one or more components of the light-harvesting complex of photosystem II.	tmpzr1t_l9r_go_relaxed.owl	LHCII catabolism													biological_process											owl:Class	
GO:0000132	biolink:NamedThing	establishment of mitotic spindle orientation	A cell cycle process that sets the alignment of mitotic spindle relative to other cellular structures.	tmpzr1t_l9r_go_relaxed.owl	establishment of spindle orientation involved in mitotic cell cycle|mitotic spindle orientation|orienting of mitotic spindle|establishment of spindle orientation during mitosis											GO:0030607|GO:0030609		biological_process											owl:Class	
GO:0061380	biolink:NamedThing	superior colliculus development	The process whose specific outcome is the progression of the superior colliculus over time, from its formation to the mature structure. The superior colliculus is also known as the optic tectum or simply tectum and is a paired structure that forms a major component of the vertebrate midbrain.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-11-09T09:51:00Z					biological_process											owl:Class	
GO:0051600	biolink:NamedThing	regulation of endocytosis by exocyst localization	Any process in which an exocyst is transported to, or maintained in, a specific location that results in the modulation of endocytosis. An exocyst is a protein complex peripherally associated with the plasma membrane that determines where vesicles dock and fuse.	tmpzr1t_l9r_go_relaxed.owl	relocation of endocytosis|spatial regulation of endocytosis|regulation of site selection of endocytosis|regulation of endocytosis by exocyst localisation													biological_process											owl:Class	
GO:0070992	biolink:NamedThing	translation initiation complex	A ribonucleoprotein complex that contains a ribosome, mRNA, and initiator tRNA; the functional ribosome is at the AUG, with the methionyl/formyl-methionyl-tRNA positioned at the P site.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-10-30T01:23:52Z					cellular_component											owl:Class	
GO:0042509	biolink:NamedThing	regulation of tyrosine phosphorylation of STAT protein	Any process that modulates the frequency, rate or extent of the introduction of a phosphate group to a tyrosine residue of a STAT (Signal Transducer and Activator of Transcription) protein.	tmpzr1t_l9r_go_relaxed.owl	regulation of tyrosine phosphorylation of Stat5 protein|regulation of tyrosine phosphorylation of Stat1 protein|regulation of tyrosine phosphorylation of Stat6 protein|regulation of tyrosine phosphorylation of Stat3 protein|regulation of tyrosine phosphorylation of Stat2 protein|regulation of tyrosine phosphorylation of Stat7 protein|regulation of tyrosine phosphorylation of Stat4 protein											GO:0042528|GO:0042516|GO:0042522|GO:0042513|GO:0042525|GO:0042510|GO:0042519		biological_process											owl:Class	
GO:1902607	biolink:NamedThing	negative regulation of large conductance calcium-activated potassium channel activity	Any process that stops, prevents or reduces the frequency, rate or extent of large conductance calcium-activated potassium channel activity.	tmpzr1t_l9r_go_relaxed.owl	inhibition of large conductance calcium-activated potassium channel activity|down regulation of large conductance KCa channels|downregulation of BK calcium-activated potassium channel activity|negative regulation of BK calcium-activated potassium channel activity|down-regulation of large conductance calcium-activated potassium channel activity|inhibition of BK calcium-activated potassium channel activity|down-regulation of BK KCa channels|down regulation of BK KCa channels|down regulation of BK channel activity|downregulation of large conductance KCa channels|down-regulation of large conductance KCa channels|downregulation of large conductance calcium-activated potassium channel activity|downregulation of BK channel activity|down regulation of BK calcium-activated potassium channel activity|down regulation of large conductance calcium-activated potassium channel activity|downregulation of BK KCa channels|negative regulation of BK channel activity|inhibition of BK KCa channels|down-regulation of BK channel activity|negative regulation of BK KCa channels|inhibition of BK channel activity|negative regulation of large conductance KCa channels|down-regulation of BK calcium-activated potassium channel activity|inhibition of large conductance KCa channels							sl	2014-01-02T18:51:12Z					biological_process											owl:Class	
GO:0075187	biolink:NamedThing	hyphopodium formation	The process in which a specialized structure, consisted of stalked, thick-walled, lobed cells of vegetative epiphytic hyphae, is formed, to attach and penetrate the host surface. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	hyphopodium formation on or near host													biological_process											owl:Class	
GO:0032609	biolink:NamedThing	interferon-gamma production	The appearance of interferon-gamma due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Interferon-gamma is also known as type II interferon.	tmpzr1t_l9r_go_relaxed.owl	type II IFN production|type II interferon production|IFNG production|interferon-gamma secretion|interferon-gamma biosynthetic process											GO:0072643|GO:0042095		biological_process											owl:Class	
GO:0010998	biolink:NamedThing	regulation of translational initiation by eIF2 alpha phosphorylation	Any process that modulates the frequency, rate or extent of translation initiation in response to stress by the phosphorylation of eIF2 alpha.	tmpzr1t_l9r_go_relaxed.owl	eIF2 alpha phosphorylation in response to stress|regulation of translational initiation by eIF2 alpha phosphorylation in response to stress					Consider also annotating to 'eukaryotic translation initiation factor 2alpha kinase activity ; GO:0004694'.		tb	2009-06-10T11:27:47Z					biological_process											owl:Class	
GO:0099625	biolink:NamedThing	ventricular cardiac muscle cell membrane repolarization	The process in which ions are transported across the plasma membrane of a ventricular cardiac muscle cell such that the membrane potential changes in the repolarizing direction, toward the steady state potential. For example, the repolarization during an action potential is from a positive membrane potential towards a negative resting potential.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0019093	biolink:NamedThing	mitochondrial RNA localization	Any process in which mitochondrial RNA is transported to, or maintained in, a specific location.	tmpzr1t_l9r_go_relaxed.owl	establishment and maintenance of mitochondrial RNA localization|mtRNA localization|mitochondrial RNA localisation													biological_process											owl:Class	
GO:0051136	biolink:NamedThing	regulation of NK T cell differentiation	Any process that modulates the frequency, rate or extent of natural killer T cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	regulation of NK T cell development|regulation of NK T-lymphocyte differentiation|regulation of NK T-cell differentiation|regulation of natural killer T cell differentiation|regulation of NT cell differentiation|regulation of natural T cell differentiation|regulation of NKT cell differentiation|regulation of NK T lymphocyte differentiation					Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.								biological_process											owl:Class	
GO:0001865	biolink:NamedThing	NK T cell differentiation	The process in which a precursor cell type acquires the specialized features of a NK T cell.	tmpzr1t_l9r_go_relaxed.owl	NKT cell differentiation|NT cell differentiation|NK T lymphocyte differentiation|natural killer T cell differentiation|NK T cell development|NK T-cell differentiation|NK T-lymphocyte differentiation|natural T cell differentiation					Note that NK T cells are a distinct lineage of T cells expressing natural killer cell markers and having T cell receptors characterized by the usage of a restricted repertoire of variable region gene segments. Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.								biological_process											owl:Class	
GO:0032775	biolink:NamedThing	DNA methylation on adenine	The covalent transfer of a methyl group to N-6 of adenine in a DNA molecule.	tmpzr1t_l9r_go_relaxed.owl	adenine methylation													biological_process											owl:Class	
GO:0090697	biolink:NamedThing	post-embryonic plant organ morphogenesis	Morphogenesis, during the post-embryonic phase, of a plant tissue or tissues that work together to perform a specific function or functions. Morphogenesis pertains to process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.	tmpzr1t_l9r_go_relaxed.owl								tb	2016-08-25T17:04:35Z					biological_process											owl:Class	
GO:1905534	biolink:NamedThing	positive regulation of leucine import across plasma membrane	Any process that activates or increases the frequency, rate or extent of leucine import across plasma membrane.	tmpzr1t_l9r_go_relaxed.owl	activation of leucine import into cell|upregulation of leucine import into cell|activation of L-leucine import into cell|up-regulation of leucine import into cell|up-regulation of L-leucine import into cell|positive regulation of leucine import into cell|positive regulation of L-leucine import into cell|up regulation of L-leucine import into cell|up regulation of leucine import into cell|upregulation of L-leucine import into cell							vw	2014-06-25T13:10:04Z			GO:1903130		biological_process											owl:Class	
GO:0051245	biolink:NamedThing	negative regulation of cellular defense response	Any process that stops, prevents, or reduces the rate of the cellular defense response.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of cellular defence response|down-regulation of cellular defense response|downregulation of cellular defense response|down regulation of cellular defense response|inhibition of cellular defense response													biological_process											owl:Class	
GO:0015746	biolink:NamedThing	citrate transport	The directed movement of citrate, 2-hydroxy-1,2,3-propanetricarboyxlate, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0033641	biolink:NamedThing	modulation by symbiont of host response to pH	Any process in which an organism modulates a change in state or activity of a host cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0071928	biolink:NamedThing	tyramine signaling pathway	The series of molecular signals generated as a consequence of tyramine binding to a cell surface receptor.	tmpzr1t_l9r_go_relaxed.owl	tyramine signalling pathway							mah	2010-09-28T01:20:10Z					biological_process											owl:Class	
GO:0010754	biolink:NamedThing	negative regulation of cGMP-mediated signaling	Any process that decreases the rate, frequency or extent of cGMP-mediated signaling. cGMP-mediated signaling is a series of molecular signals in which a cell uses cyclic GMP to convert an extracellular signal into a response.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of cGMP-mediated signalling													biological_process											owl:Class	
GO:0019934	biolink:NamedThing	cGMP-mediated signaling	Any intracellular signal transduction in which the signal is passed on within the cell via cyclic GMP (cGMP). Includes production of cGMP, and downstream effectors that further transmit the signal within the cell.	tmpzr1t_l9r_go_relaxed.owl	cGMP-mediated signalling													biological_process											owl:Class	
GO:0048245	biolink:NamedThing	eosinophil chemotaxis	The movement of an eosinophil in response to an external stimulus.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0044337	biolink:NamedThing	canonical Wnt signaling pathway involved in positive regulation of apoptotic process	The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes involved in the positive regulation of apoptotic process.	tmpzr1t_l9r_go_relaxed.owl	canonical Wnt-activated signaling pathway involved in positive regulation of apoptotic process|canonical Wnt receptor signaling pathway involved in positive regulation of apoptotic process|canonical Wnt receptor signaling pathway involved in positive regulation of apoptosis|canonical Wnt receptor signalling pathway involved in positive regulation of apoptosis							jl	2010-08-20T03:08:24Z					biological_process											owl:Class	
GO:0051466	biolink:NamedThing	positive regulation of corticotropin-releasing hormone secretion	Any process that activates or increases the frequency, rate or extent of the regulated release of corticotropin-releasing hormone from a cell.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of CRF secretion|activation of corticotropin-releasing hormone secretion|up-regulation of corticotropin-releasing hormone secretion|positive regulation of corticotropin-releasing factor secretion|up regulation of corticotropin-releasing hormone secretion|stimulation of corticotropin-releasing hormone secretion|upregulation of corticotropin-releasing hormone secretion|positive regulation of CRH secretion													biological_process											owl:Class	
GO:0043396	biolink:NamedThing	corticotropin-releasing hormone secretion	The regulated release of corticotropin-releasing hormone (CRH), a polypeptide hormone involved in the stress response. CRH is produced by the hypothalamus and stimulates corticotropic cells of the anterior lobe of the pituitary to produce corticotropic hormone (CTH) and other biologically active substances e.g. 2-endorphin, release of CRH is affected by serum levels of cortisol, by stress and by the sleep/wake cycle.	tmpzr1t_l9r_go_relaxed.owl	CRH secretion|corticotropin-releasing factor secretion|CRF secretion													biological_process											owl:Class	
GO:0140311	biolink:NamedThing	protein sequestering activity	The selective interaction of a protein with a specific protein, to prevent it from interacting with other partners or inhibiting its localization to other areas of the cell.	tmpzr1t_l9r_go_relaxed.owl								pg	2019-03-26T14:34:16Z					molecular_function											owl:Class	
GO:0033007	biolink:NamedThing	negative regulation of mast cell activation involved in immune response	Any process that stops, prevents, or reduces the frequency, rate, or extent of mast cell activation as part of an immune response.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of mast cell activation during immune response													biological_process											owl:Class	
GO:0086015	biolink:NamedThing	SA node cell action potential	An action potential that occurs in a sinoatrial node cardiac muscle cell.	tmpzr1t_l9r_go_relaxed.owl	SA node cardiac muscle cell action potential|sinoatrial node cardiac muscle cell action potential|SAN cardiac muscle cell action potential|sinus node cardiac muscle cell action potential							tb	2011-11-10T08:50:15Z					biological_process											owl:Class	
GO:0140540	biolink:NamedThing	negative regulation melanotic encapsulation of foreign target	Any process that stops, prevents or reduces the frequency, rate or extent of melanotic encapsulation of foreign target.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/16749						pg	2020-11-07T08:17:40Z					biological_process											owl:Class	
GO:0035011	biolink:NamedThing	melanotic encapsulation of foreign target	Formation of a multilayered, melanized sheath of cells around a foreign invader.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1990936	biolink:NamedThing	vascular associated smooth muscle cell dedifferentiation	The process in which a vascular smooth muscle cell (a non-striated, elongated, spindle-shaped cell found lining the blood vessels) loses the structural or functional features that characterize it in the mature organism, or some other relatively stable phase of the organism's life history. Under certain conditions, these cells can revert back to the features of the stem cells that were their ancestors.	tmpzr1t_l9r_go_relaxed.owl	vascular smooth muscle cell dedifferentiation							tb	2016-03-22T20:25:11Z					biological_process											owl:Class	
GO:0046852	biolink:NamedThing	positive regulation of bone remodeling	Any process that activates or increases the frequency, rate or extent of bone remodeling.	tmpzr1t_l9r_go_relaxed.owl	activation of bone remodeling|stimulation of bone remodeling|up regulation of bone remodeling|up-regulation of bone remodeling|upregulation of bone remodeling													biological_process											owl:Class	
GO:0046849	biolink:NamedThing	bone remodeling	The continuous turnover of bone matrix and mineral that involves first, an increase in resorption (osteoclastic activity) and later, reactive bone formation (osteoblastic activity). The process of bone remodeling takes place in the adult skeleton at discrete foci. The process ensures the mechanical integrity of the skeleton throughout life and plays an important role in calcium homeostasis. An imbalance in the regulation of bone resorption and bone formation results in many of the metabolic bone diseases, such as osteoporosis.	tmpzr1t_l9r_go_relaxed.owl	bone remodelling				Wikipedia:Bone_remodeling									biological_process											owl:Class	
GO:0021690	biolink:NamedThing	cerebellar molecular layer maturation	A developmental process, independent of morphogenetic (shape) change, that is required for the cerebellar molecular layer to attain its fully functional state. The molecular layer is the outermost layer of the cerebellar cortex. It contains the parallel fibers of the granule cells, interneurons such as stellate and basket cells, and the dendrites of the underlying Purkinje cells.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0021679	biolink:NamedThing	cerebellar molecular layer development	The process whose specific outcome is the progression of the cerebellar molecular layer nerve over time, from its formation to the mature structure. The molecular layer is the outermost layer of the cerebellar cortex. It contains the parallel fibers of the granule cells, interneurons such as stellate and basket cells, and the dendrites of the underlying Purkinje cells.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1900051	biolink:NamedThing	positive regulation of histone exchange	Any process that activates or increases the frequency, rate or extent of histone exchange.	tmpzr1t_l9r_go_relaxed.owl	activation of histone replacement|activation of histone exchange|up-regulation of histone exchange|upregulation of histone chaperone|upregulation of histone replacement|up regulation of histone exchange|activation of histone chaperone|up-regulation of histone replacement|positive regulation of histone replacement|up regulation of histone replacement|up-regulation of histone chaperone|upregulation of histone exchange|up regulation of histone chaperone|positive regulation of histone chaperone							se	2012-01-19T10:59:12Z					biological_process											owl:Class	
GO:0060608	biolink:NamedThing	cell-cell adhesion involved in neural tube closure	The attachment of one cell to another cell along the edges of two epithelial folds, giving rise to the lumen of the neural tube.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-05-15T09:56:14Z					biological_process											owl:Class	
GO:0001843	biolink:NamedThing	neural tube closure	The last step in the formation of the neural tube, where the paired neural folds are brought together and fuse at the dorsal midline.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0100026	biolink:NamedThing	positive regulation of DNA repair by transcription from RNA polymerase II promoter	Any transcription from RNA polymerase II promoter process that positively regulates DNA repair.	tmpzr1t_l9r_go_relaxed.owl								cjm	2015-04-02T04:13:19Z					biological_process											owl:Class	
GO:0003088	biolink:NamedThing	positive regulation of the force of heart contraction by circulating epinephrine	The process in which the secretion of epinephrine into the bloodstream modulates the force of heart muscle contraction.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of heart contraction by circulating epinephrine|increased force of heart contraction by epinephrine in the bloodstream|positive regulation of heart contraction by circulating adrenaline|increased force of heart contraction by circulating adrenaline													biological_process											owl:Class	
GO:0003089	biolink:NamedThing	positive regulation of the force of heart contraction by circulating epinephrine-norepinephrine	Any process that increases the force with which the cardiac muscles of the heart pump blood through the circulatory system as a result of the presence of epinephrine or norepinephrine in the bloodstream.	tmpzr1t_l9r_go_relaxed.owl	increased force of heart contraction by circulating epinephrine-norepinephrine|increased force of heart contraction by epinephrine-norepinephrine in the blood stream|increased force of heart contraction by circulating adrenaline-noradrenaline|positive regulation of heart contraction by circulating adrenaline-noradrenaline|positive regulation of heart contraction by circulating epinephrine-norepinephrine													biological_process											owl:Class	
GO:0070314	biolink:NamedThing	G1 to G0 transition	A cell cycle arrest process that results in arrest during G1 phase, whereupon the cell enters a specialized resting state known as G0 or quiescence.	tmpzr1t_l9r_go_relaxed.owl	stationary phase|establishment of cell quiescence|cell cycle quiescence|G1/G0 transition													biological_process											owl:Class	
GO:0051568	biolink:NamedThing	histone H3-K4 methylation	The modification of histone H3 by addition of one or more methyl groups to lysine at position 4 of the histone.	tmpzr1t_l9r_go_relaxed.owl	histone H3 K4 methylation|histone lysine H3 K4 methylation|histone H3K4me													biological_process											owl:Class	
GO:0120224	biolink:NamedThing	larynx development	The biological process whose specific outcome is the progression of a larynx from an initial condition to its mature state. This process begins with the formation of the larynx and ends with the mature structure. A larynx is a continuation of the pharynx that is involved in breathing, sound production, and protecting the trachea against food aspiration.	tmpzr1t_l9r_go_relaxed.owl								krc	2020-02-24T17:13:10Z					biological_process											owl:Class	
GO:0090050	biolink:NamedThing	positive regulation of cell migration involved in sprouting angiogenesis	Any process that increases the frequency, rate or extent of cell migration involved in sprouting angiogenesis. Cell migration involved in sprouting angiogenesis is the orderly movement of endothelial cells into the extracellular matrix in order to form new blood vessels contributing to the process of sprouting angiogenesis.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-08-07T10:41:09Z					biological_process											owl:Class	
GO:0002042	biolink:NamedThing	cell migration involved in sprouting angiogenesis	The orderly movement of endothelial cells into the extracellular matrix in order to form new blood vessels involved in sprouting angiogenesis.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1900293	biolink:NamedThing	positive regulation of galactotriose transport	Any process that activates or increases the frequency, rate or extent of galactotriose transport.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of galactotriose transport|up regulation of galactotriose transport|upregulation of galactotriose transport|activation of galactotriose transport							tt	2012-04-05T07:26:28Z					biological_process											owl:Class	
GO:0015592	biolink:NamedThing	methylgalactoside transmembrane transporter activity	Enables the transfer of methylgalactoside from one side of a membrane to the other. Methylgalactoside is a compound in which the H of the OH group on carbon-1 of galactose is replaced by a methyl group.	tmpzr1t_l9r_go_relaxed.owl	galactose/glucose (methylgalactoside) porter activity													molecular_function											owl:Class	
GO:0015765	biolink:NamedThing	methylgalactoside transport	The directed movement of methylgalactoside into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Methylgalactoside is a compound in which the H of the OH group on carbon-1 of galactose is replaced by a methyl group.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1904395	biolink:NamedThing	positive regulation of skeletal muscle acetylcholine-gated channel clustering	Any process that activates or increases the frequency, rate or extent of skeletal muscle acetylcholine-gated channel clustering.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of skeletal muscle AChR clustering|positive regulation of skeletal muscle AChR clustering|upregulation of skeletal muscle acetylcholine-gated channel clustering|activation of skeletal muscle AChR clustering|up-regulation of skeletal muscle acetylcholine-gated channel clustering|up-regulation of skeletal muscle nicotinic acetylcholine receptor clustering|positive regulation of skeletal muscle nicotinic acetylcholine receptor clustering|up regulation of skeletal muscle AChR clustering|up regulation of skeletal muscle acetylcholine-gated channel clustering|activation of skeletal muscle acetylcholine-gated channel clustering|up regulation of skeletal muscle nicotinic acetylcholine receptor clustering|activation of skeletal muscle nicotinic acetylcholine receptor clustering|upregulation of skeletal muscle AChR clustering|upregulation of skeletal muscle nicotinic acetylcholine receptor clustering							sl	2015-06-23T19:23:37Z					biological_process											owl:Class	
GO:0098027	biolink:NamedThing	virus tail, sheath	The external contractile envelope of the tail of some viruses. Its contraction ensures ejection of the virus DNA into the host cytoplasm.	tmpzr1t_l9r_go_relaxed.owl	bacteriophage tail sheath							bm	2012-07-19T14:23:27Z					cellular_component											owl:Class	
GO:1902758	biolink:NamedThing	bis(molybdopterin guanine dinucleotide)molybdenum biosynthetic process	The chemical reactions and pathways resulting in the formation of bis(molybdopterin guanine dinucleotide)molybdenum.	tmpzr1t_l9r_go_relaxed.owl	bis(molybdopterin guanine dinucleotide)molybdenum biosynthesis|bis(molybdopterin guanine dinucleotide)molybdenum synthesis|bis(molybdopterin guanine dinucleotide)molybdenum formation|bis-Mo-molybdopterin-guanine dinucleotide cofactor biosynthetic process|bis(molybdopterin guanine dinucleotide)molybdenum anabolism				MetaCyc:PWY-5964			dph	2014-03-06T13:58:18Z			GO:0061600		biological_process											owl:Class	
GO:0061603	biolink:NamedThing	molybdenum cofactor guanylyltransferase activity	Catalysis of the reaction GTP + molybdenum cofactor = diphosphate + guanylyl molybdenum cofactor.	tmpzr1t_l9r_go_relaxed.owl					EC:2.7.7.77|RHEA:34243			dph	2014-02-10T14:54:36Z					molecular_function											owl:Class	
GO:0002472	biolink:NamedThing	macrophage antigen processing and presentation	The process in which a macrophage expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1902418	biolink:NamedThing	(+)-abscisic acid D-glucopyranosyl ester transmembrane transport	The process in which (+)-abscisic acid D-glucopyranosyl este is transported across a membrane.	tmpzr1t_l9r_go_relaxed.owl	abscisic acid glucosyl ester transmembrane transport|ABA-GE transmembrane transport							tb	2013-09-16T22:37:20Z					biological_process											owl:Class	
GO:1904283	biolink:NamedThing	negative regulation of antigen processing and presentation of endogenous peptide antigen via MHC class I	Any process that stops, prevents or reduces the frequency, rate or extent of antigen processing and presentation of endogenous peptide antigen via MHC class I.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of antigen processing and presentation of endogenous peptide antigen via MHC class I|downregulation of antigen processing and presentation of endogenous peptide antigen via MHC class I|downregulation of endogenous peptide antigen processing and presentation via MHC class I|down-regulation of endogenous peptide antigen processing and presentation via MHC class I|negative regulation of endogenous peptide antigen processing and presentation via MHC class I|inhibition of endogenous peptide antigen processing and presentation via MHC class I|down regulation of endogenous peptide antigen processing and presentation via MHC class I|down regulation of antigen processing and presentation of endogenous peptide antigen via MHC class I|inhibition of antigen processing and presentation of endogenous peptide antigen via MHC class I							rl	2015-06-04T12:05:34Z					biological_process											owl:Class	
GO:0072677	biolink:NamedThing	eosinophil migration	The movement of an eosinophil within or between different tissues and organs of the body.	tmpzr1t_l9r_go_relaxed.owl								mah	2011-02-22T03:39:31Z					biological_process											owl:Class	
GO:1900291	biolink:NamedThing	regulation of galactotriose transport	Any process that modulates the frequency, rate or extent of galactotriose transport.	tmpzr1t_l9r_go_relaxed.owl								tt	2012-04-05T07:25:58Z					biological_process											owl:Class	
GO:0050823	biolink:NamedThing	peptide antigen stabilization	Any process involved in maintaining the structure and integrity of a peptide antigen and preventing it from being degraded.	tmpzr1t_l9r_go_relaxed.owl	peptide antigen stabilization activity													biological_process											owl:Class	
GO:0000464	biolink:NamedThing	endonucleolytic cleavage in ITS1 upstream of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	Endonucleolytic cleavage within Internal Transcribed Spacer 1 (ITS1) upstream of the 5.8S rRNA derived from an originally tricistronic rRNA transcript that contained the Small Subunit (SSU) rRNA, the 5.8S rRNA, and the Large Subunit (LSU) rRNA in that order from 5' to 3' along the primary transcript. In S. cerevisiae, this endonucleolytic cleavage within ITS1 initiates the maturation of the LSU and the 5.8S rRNAs.	tmpzr1t_l9r_go_relaxed.owl	endonucleolytic cleavage at A3													biological_process											owl:Class	
GO:0015161	biolink:NamedThing	lipid III floppase activity	Enables the transbilayer of capsular-polysaccharides (Und-PP-GlcNAc-ManNAcA-Fuc4NAc (lipid III)) from the inner to the outer leaflet of the cytoplasmic membrane during the assembly of ECA. Capsular polysaccharides make up the capsule, a protective structure surrounding some species of bacteria and fungi.	tmpzr1t_l9r_go_relaxed.owl	undecaprenol-pyrophosphate O-antigen flippase activity|capsular polysaccharide transmembrane transporter activity|capsule polysaccharide transporter activity				TC:2.A.66.2.12|TC:2.A.66.2.3									molecular_function											owl:Class	
GO:0060777	biolink:NamedThing	compound leaf morphogenesis	The leaf morphogenesis process that results in the shaping of a compound leaf. A compound leaf is a leaf having two or more distinct leaflets that are evident as such from early in development.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-07-25T07:12:30Z					biological_process											owl:Class	
GO:1903145	biolink:NamedThing	actin filament of cell cortex of cell tip	Any actin filament that is part of a cell cortex of cell tip.	tmpzr1t_l9r_go_relaxed.owl	microfilament of cell cortex of cell end|actin filament of cell cortex of cell end|microfilament of cell cortex of cell tip							vw	2014-07-06T16:24:01Z					cellular_component											owl:Class	
GO:0051285	biolink:NamedThing	cell cortex of cell tip	The region directly beneath the plasma membrane at the cell tip. The cell tip is the region at either end of the longest axis of a cylindrical or elongated cell.	tmpzr1t_l9r_go_relaxed.owl	cell cortex of cell end													cellular_component											owl:Class	
GO:0021814	biolink:NamedThing	cell motility involved in cerebral cortex radial glia guided migration	The movement of a cell along the process of a radial glial cell involved in cerebral cortex glial-mediated radial migration.	tmpzr1t_l9r_go_relaxed.owl	cell locomotion involved in cerebral cortex glial-mediated radial migration|cell locomotion involved in cerebral cortex radial glia guided migration													biological_process											owl:Class	
GO:0021801	biolink:NamedThing	cerebral cortex radial glia-guided migration	The radial migration of neuronal or glial precursor cells along radial glial cells during the development of the cerebral cortex.	tmpzr1t_l9r_go_relaxed.owl	cerebral cortex radial glia-dependent cell migration|cerebral cortex radial glia guided migration|glial-guided locomotion													biological_process											owl:Class	
GO:0062029	biolink:NamedThing	positive regulation of stress granule assembly	Any process that starts or increases the rate, frequency or extent of stress-granule assembly, the aggregation, arrangement and bonding together of proteins and RNA molecules to form a stress granule.	tmpzr1t_l9r_go_relaxed.owl								dph	2018-04-16T19:17:10Z					biological_process											owl:Class	
GO:0097694	biolink:NamedThing	establishment of RNA localization to telomere	The directed movement of RNA to a specific location in the telomeric region of a chromosome.	tmpzr1t_l9r_go_relaxed.owl	establishment of RNA localisation to telomere							pr	2015-12-22T09:33:43Z					biological_process											owl:Class	
GO:0043668	biolink:NamedThing	exine	The outer layer of the pollen grain wall which is composed primarily of sporopollenin.	tmpzr1t_l9r_go_relaxed.owl						Note that the exine is highly resistant to strong acids and bases.								cellular_component											owl:Class	
GO:0002832	biolink:NamedThing	negative regulation of response to biotic stimulus	Any process that stops, prevents, or reduces the frequency, rate, or extent of a response to biotic stimulus.	tmpzr1t_l9r_go_relaxed.owl	downregulation of response to biotic stimulus|inhibition of response to biotic stimulus|down regulation of response to biotic stimulus|down-regulation of response to biotic stimulus					Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.								biological_process											owl:Class	
GO:0097545	biolink:NamedThing	axonemal outer doublet	Part of an axoneme consisting in a doublet microtubule. Nine of these outer doublets form the 9+0 axoneme, while the 9+2 axoneme also contains a central pair. Dynein arms attached to the doublets provide the mechanism of movement of the cilium.	tmpzr1t_l9r_go_relaxed.owl	axoneme outer doublet|outer-doublet microtubules|outer doublet							pr	2013-12-12T11:19:29Z					cellular_component											owl:Class	
GO:0006386	biolink:NamedThing	termination of RNA polymerase III transcription	The process in which transcription by RNA polymerase III is terminated; Pol III has an intrinsic ability to terminate transcription upon incorporation of 4 to 6 contiguous U residues.	tmpzr1t_l9r_go_relaxed.owl	RNA polymerase III transcription termination|transcription termination from Pol III promoter|RNA polymerase III transcription termination factor activity|transcription termination from RNA polymerase III promoter											GO:0019225		biological_process											owl:Class	
GO:0051146	biolink:NamedThing	striated muscle cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a striated muscle cell; striated muscle fibers are divided by transverse bands into striations, and cardiac and voluntary muscle are types of striated muscle.	tmpzr1t_l9r_go_relaxed.owl	voluntary muscle cell differentiation													biological_process											owl:Class	
GO:0003380	biolink:NamedThing	establishment or maintenance of cytoskeleton polarity involved in gastrulation	Any cellular process that results in the specification, formation or maintenance of polarized cytoskeletal structures that contribute to the cell polarity of a migrating ameboid cell taking part in gastrulation.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-12-09T07:10:57Z					biological_process											owl:Class	
GO:0005304	biolink:NamedThing	L-valine transmembrane transporter activity	Enables the transfer of L-valine from one side of a membrane to the other. L-valine is 2-amino-3-methylbutanoic acid.	tmpzr1t_l9r_go_relaxed.owl	isoleucine/valine:sodium symporter activity|valine/tyrosine/tryptophan permease activity|leucine/isoleucine/valine porter activity|L-valine transporter activity|leucine/valine/isoleucine permease activity													molecular_function											owl:Class	
GO:0071558	biolink:NamedThing	histone H3-tri/di-methyl-lysine-27 demethylase activity	Catalysis of the removal of a methyl group from a tri- or a dimethyl-lysine residue at position 27 of the histone H3 protein. This is a dioxygenase reaction that is dependent on Fe(II) and 2-oxoglutarate.	tmpzr1t_l9r_go_relaxed.owl	histone H3K27me2 demethylase activity|histone demethylase activity (H3-K27 specific)|histone H3K27me3 demethylase activity				Reactome:R-HSA-5617887|Reactome:R-HSA-5617431|RHEA:60224|Reactome:R-HSA-3222593|EC:1.14.11.68			mah	2010-01-15T11:33:17Z					molecular_function											owl:Class	
GO:0071557	biolink:NamedThing	histone H3-K27 demethylation	The modification of histone H3 by the removal of a methyl group from lysine at position 27 of the histone.	tmpzr1t_l9r_go_relaxed.owl	H3K27 demethylation							mah	2010-01-15T10:59:50Z					biological_process											owl:Class	
GO:1905161	biolink:NamedThing	protein localization to phagocytic vesicle	A process in which a protein is transported to, or maintained in, a location within a phagocytic vesicle.	tmpzr1t_l9r_go_relaxed.owl	protein recruitment to phagosome|protein localization in phagocytic vesicle|protein localisation to phagocytic vesicle|protein localisation to phagosome|protein localisation in phagocytic vesicle							bf	2016-04-25T15:05:13Z					biological_process											owl:Class	
GO:0042800	biolink:NamedThing	histone methyltransferase activity (H3-K4 specific)	Catalysis of the reaction: S-adenosyl-L-methionine + histone H3 L-lysine (position 4) = S-adenosyl-L-homocysteine + histone H3 N6-methyl-L-lysine (position 4). This reaction is the addition of a methyl group onto lysine at position 4 of the histone H3 protein.	tmpzr1t_l9r_go_relaxed.owl	histone lysine N-methyltransferase activity (H3-K4 specific)|histone methylase activity (H3-K4 specific)|histone H3 lysine 4-specific methyltransferase activity				Reactome:R-HSA-8937050|Reactome:R-HSA-1214188|Reactome:R-HSA-8936621|Reactome:R-HSA-8865498|Reactome:R-HSA-8936481|Reactome:R-HSA-8937016|Reactome:R-HSA-3364026	Note that in some species, the methyl group may be added to a lysine in a slightly different position of the histone H3 protein, but that this term still applies.								molecular_function											owl:Class	
GO:0097566	biolink:NamedThing	left tetrad	Set of four basal bodies found in Giardia species (trophozoite stage). It comprises the left lateral basal body pair and the left middle basal body pair (i.e. the anterior, ventral, caudal and posteriolateral basal bodies located to the right of the left nucleus of the trophozoite when viewed dorsally).	tmpzr1t_l9r_go_relaxed.owl						Due to the asymmetric nature of the Giardia trophozoite, this term is defined spatially as the trophozoite is viewed from the dorsal side, with the two nuclei dorsal to the ventral disc, and the ventral disc toward the anterior.		pr	2014-02-05T16:30:43Z					cellular_component											owl:Class	
GO:0001955	biolink:NamedThing	blood vessel maturation	A developmental process, independent of morphogenetic (shape) change, that is required for a blood vessel to attain its fully functional state.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0071940	biolink:NamedThing	fungal-type cell wall assembly	The aggregation, arrangement and bonding together of a set of components to form a fungal-type cell wall.	tmpzr1t_l9r_go_relaxed.owl	fungal-type cell wall formation							mah	2010-09-30T04:59:36Z					biological_process											owl:Class	
GO:2000457	biolink:NamedThing	positive regulation of T-helper 17 cell extravasation	Any process that activates or increases the frequency, rate or extent of T-helper 17 cell extravasation.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-03-04T10:51:00Z					biological_process											owl:Class	
GO:0030703	biolink:NamedThing	eggshell formation	Construction of the eggshell, a product of the somatic follicle cell epithelium and a structure that supports the egg in a hostile environment, minimizing water loss whilst allowing gas exchanges essential for embryonic respiration.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0055108	biolink:NamedThing	Golgi to transport vesicle transport	The directed movement of proteins from the Golgi to a transport vesicle. Continuously secreted proteins are sorted into transport vesicles that fuse with the plasma membrane, releasing their contents by exocytosis.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0106128	biolink:NamedThing	negative regulation of store-operated calcium entry	Any process that stops, prevents or reduces the frequency, rate or extent of store-operated calcium entry.	tmpzr1t_l9r_go_relaxed.owl								hjd	2018-05-10T18:59:12Z					biological_process											owl:Class	
GO:0097486	biolink:NamedThing	multivesicular body lumen	The volume enclosed by the outermost membrane of a multivesicular body.	tmpzr1t_l9r_go_relaxed.owl								pr	2013-07-08T20:32:56Z					cellular_component											owl:Class	
GO:0002358	biolink:NamedThing	B cell homeostatic proliferation	The non-specific expansion of B cell populations within a whole or part of an organism to reach to a total number of B cells which will then remain stable over time in the absence of an external stimulus.	tmpzr1t_l9r_go_relaxed.owl	B lymphocyte homeostatic proliferation|B-cell homeostatic proliferation|B-lymphocyte homeostatic proliferation													biological_process											owl:Class	
GO:0042592	biolink:NamedThing	homeostatic process	Any biological process involved in the maintenance of an internal steady state.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of homeostatic process|regulation of homeostatic process|activation of homeostatic process|homeostasis|negative regulation of homeostatic process|inhibition of homeostatic process											GO:0032846|GO:0032844|GO:0032845		biological_process											owl:Class	
GO:1900951	biolink:NamedThing	negative regulation of 18-methylnonadec-1-ene biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of 18-methylnonadec-1-ene biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of 18-methylnonadec-1-ene biosynthetic process|down regulation of 18-methylnonadec-1-ene formation|inhibition of 18-methylnonadec-1-ene synthesis|down-regulation of 18-methylnonadec-1-ene formation|down regulation of 18-methylnonadec-1-ene biosynthetic process|downregulation of 18-methylnonadec-1-ene anabolism|downregulation of 18-methylnonadec-1-ene synthesis|down regulation of 18-methylnonadec-1-ene biosynthesis|down-regulation of 18-methylnonadec-1-ene synthesis|inhibition of 18-methylnonadec-1-ene anabolism|down regulation of 18-methylnonadec-1-ene anabolism|negative regulation of 18-methylnonadec-1-ene anabolism|downregulation of 18-methylnonadec-1-ene biosynthetic process|down-regulation of 18-methylnonadec-1-ene biosynthesis|negative regulation of 18-methylnonadec-1-ene biosynthesis|downregulation of 18-methylnonadec-1-ene biosynthesis|inhibition of 18-methylnonadec-1-ene biosynthetic process|down-regulation of 18-methylnonadec-1-ene anabolism|downregulation of 18-methylnonadec-1-ene formation|inhibition of 18-methylnonadec-1-ene formation|inhibition of 18-methylnonadec-1-ene biosynthesis|negative regulation of 18-methylnonadec-1-ene synthesis|down regulation of 18-methylnonadec-1-ene synthesis|negative regulation of 18-methylnonadec-1-ene formation							tt	2012-06-14T03:23:55Z					biological_process											owl:Class	
GO:1900369	biolink:NamedThing	negative regulation of RNA interference	Any process that stops, prevents or reduces the frequency, rate or extent of RNA interference.	tmpzr1t_l9r_go_relaxed.owl	down regulation of RNAi|inhibition of RNAi|inhibition of posttranscriptional gene silencing by siRNA|downregulation of RNA interference|down-regulation of RNA interference|downregulation of posttranscriptional gene silencing by siRNA|down regulation of posttranscriptional gene silencing by siRNA|down regulation of RNA interference|negative regulation of RNAi|inhibition of RNA interference|negative regulation of posttranscriptional gene silencing by siRNA|downregulation of RNAi|down-regulation of RNAi|down-regulation of posttranscriptional gene silencing by siRNA							kmv	2012-04-13T08:28:50Z					biological_process											owl:Class	
GO:0042779	biolink:NamedThing	tRNA 3'-trailer cleavage	Cleavage of the 3'-end of the pre-tRNA as part of the process of generating the mature 3'-end of the tRNA; may involve endonucleolytic or exonucleolytic cleavage, or both.	tmpzr1t_l9r_go_relaxed.owl	tRNA 3'-end cleavage|removal of tRNA 3'-trailer sequence													biological_process											owl:Class	
GO:0042780	biolink:NamedThing	tRNA 3'-end processing	The process in which the 3' end of a pre-tRNA molecule is converted to that of a mature tRNA.	tmpzr1t_l9r_go_relaxed.owl	tRNA 3' processing													biological_process											owl:Class	
GO:0010220	biolink:NamedThing	positive regulation of vernalization response	Any process that activates or induces the rate of the vernalization response, by which induction of flowering is normally caused by extended exposure to cold temperatures.	tmpzr1t_l9r_go_relaxed.owl	stimulation of vernalization response|up regulation of vernalization response|upregulation of vernalization response|activation of vernalization response|up-regulation of vernalization response													biological_process											owl:Class	
GO:0010048	biolink:NamedThing	vernalization response	The process of thermal induction in plants in which flowering is promoted by exposure to low temperatures.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0032634	biolink:NamedThing	interleukin-5 production	The appearance of interleukin-5 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	tmpzr1t_l9r_go_relaxed.owl	IL-5 production|interleukin-5 biosynthetic process|interleukin-5 secretion											GO:0072603|GO:0042225		biological_process											owl:Class	
GO:0097567	biolink:NamedThing	right tetrad	Set of four basal bodies found in Giardia species (trophozoite stage). It comprises the right lateral basal body pair and the right middle basal body pair (i.e. the anterior, ventral, caudal and posteriolateral basal bodies located to the left of the right nucleus of the trophozoite when viewed dorsally).	tmpzr1t_l9r_go_relaxed.owl						Due to the asymmetric nature of the Giardia trophozoite, this term is defined spatially as the trophozoite is viewed from the dorsal side, with the two nuclei dorsal to the ventral disc, and the ventral disc toward the anterior.		pr	2014-02-05T16:32:33Z					cellular_component											owl:Class	
GO:0150067	biolink:NamedThing	regulation of tubulin deacetylase activity	Any process that modulates the frequency, rate or extent of tubulin deacetylase activity.	tmpzr1t_l9r_go_relaxed.owl								bc	2018-07-24T10:29:49Z					biological_process											owl:Class	
GO:0019533	biolink:NamedThing	cellobiose transport	The directed movement of cellobiose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Cellobiose, or 4-O-beta-D-glucopyranosyl-D-glucose, is a disaccharide that represents the basic repeating unit of cellulose.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0010780	biolink:NamedThing	meiotic DNA double-strand break formation involved in reciprocal meiotic recombination	The cell cycle process in which double-strand breaks are generated at defined hotspots throughout the genome during meiosis I resulting in meiotic recombination. Meiotic recombination is the cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0034456	biolink:NamedThing	UTP-C complex	A protein complex that forms a subcomplex of the 90S preribosome. In S. cerevisiae, it is composed of Rrp7p, Utp22p, Ckb1p, Cka1p, Ckb2p and Cka2p.	tmpzr1t_l9r_go_relaxed.owl	Rrp7p-containing subcomplex of 90S preribosome					Note that the term name uses Saccharomyces gene product names because no other names have yet arisen for this complex; the term nevertheless can be used for analogous complexes in other eukaryotes, and the name can be changed if better wording is found.								cellular_component											owl:Class	
GO:0061984	biolink:NamedThing	catabolite repression	A process in which the presence of one nutrient source leads to a decrease in the frequency, rate, or extent of processes involved in the metabolism of other nutrient sources.	tmpzr1t_l9r_go_relaxed.owl								dph	2018-02-15T16:34:14Z					biological_process											owl:Class	
GO:0021607	biolink:NamedThing	accessory nerve morphogenesis	The process in which the anatomical structure of the accessory nerve is generated and organized. The spinal branch of this motor nerve innervates the trapezius and the sternocleidomastoid muscles. The cranial branch joins the vagus nerve and innervates the same targets as the vagus nerve.	tmpzr1t_l9r_go_relaxed.owl	CN XI morphogenesis													biological_process											owl:Class	
GO:0000407	biolink:NamedThing	phagophore assembly site	Punctate structures proximal to the endoplasmic reticulum which are the sites where the Atg machinery assembles upon autophagy induction.	tmpzr1t_l9r_go_relaxed.owl	PAS|pre-autophagosomal structure|perivacuolar space													cellular_component											owl:Class	
GO:0015346	biolink:NamedThing	ferric triacetylfusarinine C:proton symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ferric triacetylfusarinine C(out) + H+(out) = ferric triacetylfusarinine C(in) + H+(in).	tmpzr1t_l9r_go_relaxed.owl	ferric triacetylfusarinine C:hydrogen symporter activity													molecular_function											owl:Class	
GO:0032258	biolink:NamedThing	cytoplasm to vacuole transport by the Cvt pathway	A cytoplasm to vacuole targeting pathway that uses machinery common with autophagy. The Cvt vesicle is formed when the receptor protein, Atg19, binds to the complexes of the target protein (aminopeptidase or alpha-mannosidase homododecamers), forming the Cvt complex. Atg11 binds to Atg9 and transports the Cvt complex to the pre-autophagosome (PAS). The phagophore membrane expands around the Cvt complex (excluding bulk cytoplasm) forming the Cvt vesicle. This pathway is mostly observed in yeast.	tmpzr1t_l9r_go_relaxed.owl	cytoplasm-to-vacuole targeting|protein localization by the Cvt pathway|cytoplasm to vacuole targeting													biological_process											owl:Class	
GO:0005484	biolink:NamedThing	SNAP receptor activity	Acting as a marker to identify a membrane and interacting selectively with one or more SNAREs on another membrane to mediate membrane fusion.	tmpzr1t_l9r_go_relaxed.owl	v-SNARE activity|SNAP-25|Q-SNARE activity|SNARE|t-SNARE activity|R-SNARE activity											GO:0005485|GO:0005486		molecular_function											owl:Class	
GO:0021630	biolink:NamedThing	olfactory nerve maturation	A developmental process, independent of morphogenetic (shape) change, that is required for the olfactory nerve to attain its fully functional state. The olfactory nerve is a collection of sensory nerve rootlets that extend down from the olfactory bulb to the olfactory mucosa of the upper parts of the nasal cavity. This nerve conducts odor information to the brainstem.	tmpzr1t_l9r_go_relaxed.owl	CN I maturation													biological_process											owl:Class	
GO:0021553	biolink:NamedThing	olfactory nerve development	The process whose specific outcome is the progression of the olfactory nerve over time, from its formation to the mature structure. The olfactory nerve is a collection of sensory nerve rootlets that extend down from the olfactory bulb to the olfactory mucosa of the upper parts of the nasal cavity. This nerve conducts odor information to the brainstem.	tmpzr1t_l9r_go_relaxed.owl	CN 1 development|cranial nerve 1 development|cranial nerve I development													biological_process											owl:Class	
GO:0052721	biolink:NamedThing	regulation of apurinic/apyrimidinic endodeoxyribonuclease activity	Any process that modulates the frequency, rate or extent of apurinic/apyrimidinic (AP) endodeoxyribonuclease activity, the hydrolysis of ester linkages immediately 5' to an AP (also called abasic) site within a deoxyribonucleic acid molecule by creating internal breaks, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.	tmpzr1t_l9r_go_relaxed.owl	regulation of apyrimidinic endodeoxyribonuclease activity|regulation of apurinic endodeoxyribonuclease activity|regulation of AP endodeoxyribonuclease activity|regulation of abasic endodeoxyribonuclease activity													biological_process											owl:Class	
GO:0052720	biolink:NamedThing	class II DNA-(apurinic or apyrimidinic site) endonuclease activity	Catalysis of the hydrolysis of ester linkages immediately 5' to an apurinic/apyrimidinic (AP; also called abasic) site within a deoxyribonucleic acid molecule by creating internal breaks, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.	tmpzr1t_l9r_go_relaxed.owl	class II DNA-(apurinic or apyrimidinic site) lyase activity	https://github.com/geneontology/go-ontology/issues/13409				Class II AP endonuclease is a nuclease, but not Class I, III and IV.		pg	2017-07-24T11:46:03Z			GO:0140079		molecular_function											owl:Class	
GO:1902756	biolink:NamedThing	sulfurated eukaryotic molybdenum cofactor(2-) biosynthetic process	The chemical reactions and pathways resulting in the formation of sulfurated eukaryotic molybdenum cofactor(2-).	tmpzr1t_l9r_go_relaxed.owl	sulfurated eukaryotic molybdenum cofactor(2-) formation|sulfurated eukaryotic molybdenum cofactor(2-) biosynthesis|sulfurated eukaryotic molybdenum cofactor(2-) anabolism|sulfurated eukaryotic molybdenum cofactor(2-) synthesis				MetaCyc:PWY-6476|Reactome:R-HSA-947581			dph	2014-03-05T23:29:20Z					biological_process											owl:Class	
GO:0008265	biolink:NamedThing	Mo-molybdopterin cofactor sulfurase activity	Catalysis of the sulfurylation of the desulfo form of molybdenum cofactor (MoCo), a cofactor required for the activity of some enzymes, such as aldehyde oxidase.	tmpzr1t_l9r_go_relaxed.owl	Mo-molybdopterin cofactor sulphurase activity|molybdopterin synthase sulfurylase activity|molybdopterin cofactor sulfurase activity				EC:2.8.1.9|Reactome:R-HSA-947499									molecular_function											owl:Class	
GO:0045801	biolink:NamedThing	positive regulation of chitin-based cuticle tanning	Any process that activates or increases the frequency, rate or extent of chitin-based cuticular tanning.	tmpzr1t_l9r_go_relaxed.owl	stimulation of cuticle tanning|up-regulation of cuticle tanning|upregulation of cuticle tanning|up regulation of cuticle tanning|positive regulation of cuticle tanning|positive regulation of cuticle hardening|activation of cuticle tanning													biological_process											owl:Class	
GO:0007593	biolink:NamedThing	chitin-based cuticle sclerotization	The process of hardening of a chitin-based cuticle.	tmpzr1t_l9r_go_relaxed.owl	chitin-based cuticle tanning|cuticle hardening											GO:0045452		biological_process											owl:Class	
GO:0090390	biolink:NamedThing	phagosome acidification involved in apoptotic cell clearance	Any process that reduces the pH of the phagosome, measured by the concentration of the hydrogen ion, and occurs as a part of apoptotic cell clearance.	tmpzr1t_l9r_go_relaxed.owl								tb	2010-10-27T10:57:39Z					biological_process											owl:Class	
GO:0032391	biolink:NamedThing	photoreceptor connecting cilium	The portion of the photoreceptor cell cilium linking the photoreceptor inner and outer segments. It's considered to be equivalent to the ciliary transition zone.	tmpzr1t_l9r_go_relaxed.owl	photoreceptor cilium													cellular_component											owl:Class	
GO:0097733	biolink:NamedThing	photoreceptor cell cilium	A specialised 9+0 non-motile cilium found in photoreceptor cells. A ciliary transition zone called 'photoreceptor connecting cilium' links the photoreceptor outer segment to the inner segment.	tmpzr1t_l9r_go_relaxed.owl	photoreceptor cilium							pr	2016-09-30T10:50:11Z					cellular_component											owl:Class	
GO:0007520	biolink:NamedThing	myoblast fusion	A process in which non-proliferating myoblasts fuse to existing fibers or to myotubes to form new fibers. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0030668	biolink:NamedThing	merozoite dense granule membrane	The lipid bilayer surrounding a dense granule of the type found in apicomplexan parasites.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0020026	biolink:NamedThing	merozoite dense granule	Electron-dense organelle with a granular internal matrix found throughout the merozoite life cycle stage of apicomplexan parasites; contains proteins destined to be secreted into the parasitophorous vacuole following parasite invasion of a host cell.	tmpzr1t_l9r_go_relaxed.owl	dense body													cellular_component											owl:Class	
GO:0070211	biolink:NamedThing	Snt2C complex	A histone deacetylase complex that is part of the chromatin remodeling machinery. In Saccharomyces cerevisiae this complex contains Snt2p, Ecm5p and Rpd3p.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0044735	biolink:NamedThing	envenomation resulting in negative regulation of acid-sensing ion channel activity in other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with a resultant negative regulation in the activity of an acid-sensing ion channel (ASIC) in the bitten organism.	tmpzr1t_l9r_go_relaxed.owl	envenomation resulting in negative regulation of ASIC channel activity in other organism							jl	2012-11-06T16:05:58Z					biological_process											owl:Class	
GO:0044738	biolink:NamedThing	negative regulation of acid-sensing ion channel in other organism	Any process in which an organism negatively regulates the activity of a voltage-gated sodium channel in another organism.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of ASIC channel in other organism							jl	2012-11-06T16:55:23Z					biological_process											owl:Class	
GO:0051711	biolink:NamedThing	negative regulation of killing of cells of other organism	Any process that stops, prevents, or reduces the frequency, rate or extent of the killing by an organism of cells in another organism.	tmpzr1t_l9r_go_relaxed.owl	negative regulation by organism of programmed cell death in other organism involved in symbiotic interaction|down regulation of killing of cells of another organism|downregulation of killing of cells of another organism|down-regulation of killing of cells of another organism|inhibition of killing of cells of another organism|negative regulation of killing of cells of another organism	https://github.com/geneontology/go-ontology/issues/20287										GO:0052490		biological_process											owl:Class	
GO:0100067	biolink:NamedThing	positive regulation of spinal cord association neuron differentiation by canonical Wnt signaling pathway	Any canonical Wnt signaling pathway process that positively_regulates spinal cord association neuron differentiation.	tmpzr1t_l9r_go_relaxed.owl								cjm	2015-04-02T04:13:19Z					biological_process											owl:Class	
GO:2000877	biolink:NamedThing	negative regulation of oligopeptide transport	Any process that stops, prevents or reduces the frequency, rate or extent of oligopeptide transport.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-07-27T01:54:07Z					biological_process											owl:Class	
GO:0086054	biolink:NamedThing	bundle of His cell to Purkinje myocyte communication by electrical coupling	The process that mediates signaling interactions between a bundle of His cardiac muscle cell and a Purkinje myocyte by transfer of current between their adjacent cytoplasms via intercellular protein channels.	tmpzr1t_l9r_go_relaxed.owl	bundle of His cardiac muscle cell to Purkinje myocyte communication by electrical coupling							dph	2011-11-17T10:46:43Z					biological_process											owl:Class	
GO:0032638	biolink:NamedThing	interleukin-9 production	The appearance of interleukin-9 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	tmpzr1t_l9r_go_relaxed.owl	interleukin-9 secretion|interleukin-9 biosynthetic process|IL-9 production											GO:0072607|GO:0042229		biological_process											owl:Class	
GO:0003994	biolink:NamedThing	aconitate hydratase activity	Catalysis of the reaction: citrate = isocitrate. The reaction occurs in two steps: (1) citrate = cis-aconitate + H2O, (2) cis-aconitate + H2O = isocitrate. This reaction is the interconversion of citrate and isocitrate via the labile, enzyme-bound intermediate cis-aconitate. Water is removed from one part of the citrate molecule and added back to a different atom to form isocitrate.	tmpzr1t_l9r_go_relaxed.owl	citrate(isocitrate) hydro-lyase activity|cis-aconitase activity|citrate hydro-lyase activity|citrate(isocitrate) hydro-lyase (cis-aconitate-forming)|aconitase activity				Reactome:R-HSA-70971|Reactome:R-HSA-5690911|EC:4.2.1.3|RHEA:10336|Reactome:R-HSA-450975	This is a process composed of two reactions represented by the terms 'GO:0052632 : citrate hydro-lyase (cis-aconitate-forming) activity' and 'GO:0052633 : isocitrate hydro-lyase (cis-aconitate-forming) activity'.								molecular_function											owl:Class	
GO:0061197	biolink:NamedThing	fungiform papilla morphogenesis	The process in which the anatomical structures of the fungiform papilla are generated and organized. The fungiform papilla is a mushroom-shaped papilla of the tongue.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-07-27T12:26:40Z					biological_process											owl:Class	
GO:0061196	biolink:NamedThing	fungiform papilla development	The progression of the fungiform papilla over time, from its formation to the mature structure. The fungiform papilla is a mushroom-shaped papilla of the tongue.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-07-27T12:23:48Z					biological_process											owl:Class	
GO:0071935	biolink:NamedThing	octopamine signaling pathway involved in response to food	The series of molecular signals initiated by binding of octopamine to a receptor on the surface of the target cell that contributes to a response to a food stimulus.	tmpzr1t_l9r_go_relaxed.owl	octopamine signalling pathway involved in response to food							mah	2010-09-30T11:55:59Z					biological_process											owl:Class	
GO:0120085	biolink:NamedThing	transposon integration involved in RNA-mediated transposition	Any transposon integration that contributes to a process of RNA-mediated transposition.	tmpzr1t_l9r_go_relaxed.owl	retrotransposon integration							krc	2017-07-07T22:17:32Z					biological_process											owl:Class	
GO:0097632	biolink:NamedThing	extrinsic component of phagophore assembly site membrane	The component of the phagophore assembly site membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.	tmpzr1t_l9r_go_relaxed.owl	phagophore assembly site peripheral membrane|extrinsic to phagophore assembly site membrane|extrinsic component of pre-autophagosomal structure membrane													cellular_component											owl:Class	
GO:0050785	biolink:NamedThing	advanced glycation end-product receptor activity	Combining with advanced glycation end-products and transmitting the signal to initiate a change in cell activity. Advanced glycation end-products (AGEs) form from a series of chemical reactions after an initial glycation event (a non-enzymatic reaction between reducing sugars and free amino groups of proteins).	tmpzr1t_l9r_go_relaxed.owl	RAGE activity|AGE receptor activity													molecular_function											owl:Class	
GO:1903574	biolink:NamedThing	negative regulation of cellular response to amino acid starvation	Any process that stops, prevents or reduces the frequency, rate or extent of a cellular response to amino acid starvation.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of cellular response to amino acid starvation|inhibition of cellular response to amino acid starvation|down regulation of cellular response to amino acid starvation|downregulation of cellular response to amino acid starvation							bf	2014-10-27T16:21:02Z					biological_process											owl:Class	
GO:0034198	biolink:NamedThing	cellular response to amino acid starvation	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of amino acids.	tmpzr1t_l9r_go_relaxed.owl	GAAC response|general amino acid control response													biological_process											owl:Class	
GO:0075239	biolink:NamedThing	zoospore formation	The process in which a diploid cell undergoes meiosis, and the meiotic products acquire specialized features of asexual motile mononucleate flagellated spores called zoospores.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0060323	biolink:NamedThing	head morphogenesis	The process in which the anatomical structures of the head are generated and organized. The head is the anterior-most division of the body.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0032835	biolink:NamedThing	glomerulus development	The progression of the glomerulus over time from its initial formation until its mature state. The glomerulus is a capillary tuft which forms a close network with the visceral epithelium (podocytes) and the mesangium to form the filtration barrier and is surrounded by Bowman's capsule in nephrons of the vertebrate kidney. The glomerulus is part of the nephron and is restricted to one body segment.	tmpzr1t_l9r_go_relaxed.owl	glomerular development													biological_process											owl:Class	
GO:0005701	biolink:NamedThing	polytene chromosome chromocenter	A region at which the centric regions of polytene chromosomes are joined together.	tmpzr1t_l9r_go_relaxed.owl	polytene chromosome chromocentre													cellular_component											owl:Class	
GO:0005700	biolink:NamedThing	polytene chromosome	A type of chromosome in a polyploid cell, formed when multiple copies of homologous chromosomes are aligned side by side to give a giant chromosome in which distinct chromosome bands are readily visible.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Polytene_chromosome									cellular_component											owl:Class	
GO:0005589	biolink:NamedThing	collagen type VI trimer	A collagen heterotrimer containing type VI alpha chains in alpha1(VI)alpha2(VI)alpha3(VI) trimers; type VI collagen triple helices associate to form beaded fibrils.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0098647	biolink:NamedThing	collagen beaded filament	A supramolecular assembly of collagen trimers with a 'beads on a string'-like structure.	tmpzr1t_l9r_go_relaxed.owl	beads on a string													cellular_component											owl:Class	
GO:1903764	biolink:NamedThing	regulation of potassium ion export across plasma membrane	Any process that modulates the frequency, rate or extent of potassium ion export across the plasma membrane.	tmpzr1t_l9r_go_relaxed.owl	regulation of potassium ion export|regulation of potassium export across plasma membrane|regulation of potassium export							rl	2013-07-17T16:39:53Z			GO:1902302		biological_process											owl:Class	
GO:0061760	biolink:NamedThing	antifungal innate immune response	An defense response against a fungus mediated through an innate immune response. An innate immune response is mediated by germline encoded components that directly recognize components of potential pathogens.	tmpzr1t_l9r_go_relaxed.owl								dph	2016-03-07T08:53:08Z					biological_process											owl:Class	
GO:0012510	biolink:NamedThing	trans-Golgi network transport vesicle membrane	The lipid bilayer surrounding a vesicle transporting substances between the trans-Golgi network and other parts of the cell.	tmpzr1t_l9r_go_relaxed.owl	TGN transport vesicle membrane|trans-Golgi network constitutive secretory pathway transport vesicle membrane													cellular_component											owl:Class	
GO:0017038	biolink:NamedThing	protein import	The targeting and directed movement of proteins into a cell or organelle.  Not all import involves an initial targeting event.	tmpzr1t_l9r_go_relaxed.owl	protein uptake													biological_process											owl:Class	
GO:0044160	biolink:NamedThing	host thylakoid membrane	The pigmented membrane of any host thylakoid.	tmpzr1t_l9r_go_relaxed.owl								jl	2009-08-11T04:17:31Z					cellular_component											owl:Class	
GO:0044159	biolink:NamedThing	host thylakoid	A membranous cellular structure within the host cell that bears the photosynthetic pigments in plants, algae, and cyanobacteria. In cyanobacteria thylakoids are of various shapes and are attached to, or continuous with, the host plasma membrane. In eukaryotic host cells they are flattened, membrane-bounded disk-like structures located in the chloroplasts; in the chloroplasts of higher plants the thylakoids form dense stacks called grana. Isolated thylakoid preparations can carry out photosynthetic electron transport and the associated phosphorylation.	tmpzr1t_l9r_go_relaxed.owl								jl	2009-08-11T04:15:34Z					cellular_component											owl:Class	
GO:2000642	biolink:NamedThing	negative regulation of early endosome to late endosome transport	Any process that stops, prevents or reduces the frequency, rate or extent of early endosome to late endosome transport.	tmpzr1t_l9r_go_relaxed.owl								vk	2011-04-21T11:20:06Z					biological_process											owl:Class	
GO:0060667	biolink:NamedThing	branch elongation involved in salivary gland morphogenesis	The differential growth of the salivary branches along their axis, resulting in the growth of a branch.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-06-01T09:42:13Z					biological_process											owl:Class	
GO:0060739	biolink:NamedThing	mesenchymal-epithelial cell signaling involved in prostate gland development	Any process that mediates the transfer of information from a mesenchymal cell to an epithelial cell where it is received and interpreted contributing to the progression of the prostate gland over time.	tmpzr1t_l9r_go_relaxed.owl	mesenchymal-epithelial cell signalling involved in prostate gland development							dph	2009-06-15T09:35:08Z					biological_process											owl:Class	
GO:0047270	biolink:NamedThing	lipopolysaccharide glucosyltransferase II activity	Catalysis of the reaction: lipopolysaccharide + UDP-D-glucose = D-glucosyl-lipopolysaccharide + UDP.	tmpzr1t_l9r_go_relaxed.owl	LPS glucosyltransferase II activity|UDP-glucose:galactosyl-lipopolysaccharide alpha-D-glucosyltransferase activity|UDPglucose:galactosyl-lipopolysaccharide alpha-D-glucosyltransferase activity|uridine diphosphoglucose-galactosylpolysaccharide glucosyltransferase activity				EC:2.4.1.73|MetaCyc:2.4.1.73-RXN									molecular_function											owl:Class	
GO:0036337	biolink:NamedThing	Fas signaling pathway	A series of molecular signals initiated by the binding of a ligand to the receptor Fas on the surface of the cell, and ending with regulation of a downstream cellular process, e.g. transcription. Fas is a death domain-containing member of the tumor necrosis factor receptor (TNFR) superfamily.	tmpzr1t_l9r_go_relaxed.owl	FAS ligand-Fas signaling pathway|Fas receptor signaling pathway|CD95 signaling pathway|FasL signaling pathway|FasR signaling pathway|Apo-1 signaling pathway|Fas-FasL signaling pathway							bf	2012-09-05T10:28:11Z					biological_process											owl:Class	
GO:0097038	biolink:NamedThing	perinuclear endoplasmic reticulum	The portion of endoplasmic reticulum, the intracellular network of tubules and cisternae, that occurs near the nucleus. The lumen of the perinuclear endoplasmic reticulum is contiguous with the nuclear envelope lumen (also called perinuclear space), the region between the inner and outer nuclear membranes.	tmpzr1t_l9r_go_relaxed.owl	perinuclear ER							pr	2011-04-12T10:51:05Z					cellular_component											owl:Class	
GO:1990578	biolink:NamedThing	perinuclear endoplasmic reticulum membrane	The membrane of the perinuclear endoplasmic reticulum, which is the portion of endoplasmic reticulum, the intracellular network of tubules and cisternae, that occurs near the nucleus.	tmpzr1t_l9r_go_relaxed.owl	perinuclear ER membrane							mcc	2014-12-09T01:13:01Z					cellular_component											owl:Class	
GO:0001906	biolink:NamedThing	cell killing	Any process in an organism that results in the killing of its own cells or those of another organism, including in some cases the death of the other organism. Killing here refers to the induction of death in one cell by another cell, not cell-autonomous death due to internal or other environmental conditions.	tmpzr1t_l9r_go_relaxed.owl	necrosis													biological_process											owl:Class	
GO:1990789	biolink:NamedThing	thyroid gland epithelial cell proliferation	The multiplication or reproduction of thyroid gland epithelial cells, resulting in the expansion of the thyroid gland epithelial cell population.	tmpzr1t_l9r_go_relaxed.owl	Hurthle cell proliferation|thyroid follicular cell proliferation							sl	2015-07-02T18:50:01Z					biological_process											owl:Class	
GO:0001771	biolink:NamedThing	immunological synapse formation	The formation of an area of close contact between a lymphocyte (T-, B-, or natural killer cell) and a target cell through the clustering of particular signaling and adhesion molecules and their associated membrane rafts on both the lymphocyte and target cell, which facilitates activation of the lymphocyte, transfer of membrane from the target cell to the lymphocyte, and in some situations killing of the target cell through release of secretory granules and/or death-pathway ligand-receptor interaction.	tmpzr1t_l9r_go_relaxed.owl	formation of immunological synapse													biological_process											owl:Class	
GO:0002753	biolink:NamedThing	cytoplasmic pattern recognition receptor signaling pathway	Any series of molecular signals generated as a consequence of a cytoplasmic pattern recognition receptor (PRR) binding to one of its physiological ligands. PRRs bind pathogen-associated molecular pattern (PAMPs), structures conserved among microbial species.	tmpzr1t_l9r_go_relaxed.owl	cytoplasmic pathogen receptor signaling pathway|cytoplasmic pattern recognition receptor signalling pathway|cytoplasmic PRR signaling pathway|cytoplasmic PAMP receptor signaling pathway	https://github.com/geneontology/go-ontology/issues/18588												biological_process											owl:Class	
GO:1900699	biolink:NamedThing	negative regulation of o-orsellinic acid biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of o-orsellinic acid biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	inhibition of o-orsellinic acid anabolism|down-regulation of o-orsellinic acid biosynthesis|inhibition of o-orsellinic acid biosynthesis|down-regulation of o-orsellinic acid anabolism|down regulation of o-orsellinic acid anabolism|negative regulation of o-orsellinic acid formation|negative regulation of o-orsellinic acid biosynthesis|downregulation of o-orsellinic acid biosynthetic process|downregulation of o-orsellinic acid synthesis|downregulation of o-orsellinic acid biosynthesis|inhibition of o-orsellinic acid biosynthetic process|down regulation of o-orsellinic acid formation|down-regulation of o-orsellinic acid formation|inhibition of o-orsellinic acid synthesis|negative regulation of o-orsellinic acid anabolism|down regulation of o-orsellinic acid biosynthesis|downregulation of o-orsellinic acid formation|down regulation of o-orsellinic acid biosynthetic process|down-regulation of o-orsellinic acid synthesis|downregulation of o-orsellinic acid anabolism|inhibition of o-orsellinic acid formation|down-regulation of o-orsellinic acid biosynthetic process|down regulation of o-orsellinic acid synthesis|negative regulation of o-orsellinic acid synthesis							di	2012-05-22T04:57:08Z					biological_process											owl:Class	
GO:0009036	biolink:NamedThing	type II site-specific deoxyribonuclease activity	Catalysis of the endonucleolytic cleavage of DNA to give specific double-stranded fragments with terminal 5'-phosphates and 3' hydroxyls. Cleavage is dependent on the presence in the DNA of a specific recognition site; cleavage occurs at or very near this recognition site.	tmpzr1t_l9r_go_relaxed.owl	type II restriction enzyme activity				EC:3.1.21.4|MetaCyc:3.1.21.4-RXN									molecular_function											owl:Class	
GO:0018094	biolink:NamedThing	protein polyglycylation	The addition of glycyl units covalently bound to the gamma carboxyl group peptidyl-glutamic acid.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0201									biological_process											owl:Class	
GO:0071888	biolink:NamedThing	macrophage apoptotic process	Any apoptotic process in a macrophage, a mononuclear phagocyte present in a variety of tissues.	tmpzr1t_l9r_go_relaxed.owl	activation-induced cell death|AICD|macrophage apoptosis					Note that a lymphocyte is a cell of the B cell, T cell, or natural killer cell lineage (CL:0000542).		mah	2010-09-14T12:50:40Z					biological_process											owl:Class	
GO:0120220	biolink:NamedThing	basal body patch	The region in the apical portion of multiciliated epithelial cells where the ciliary basal bodies cluster.	tmpzr1t_l9r_go_relaxed.owl	centriolar patch							krc	2019-11-15T17:19:24Z					cellular_component											owl:Class	
GO:0045177	biolink:NamedThing	apical part of cell	The region of a polarized cell that forms a tip or is distal to a base. For example, in a polarized epithelial cell, the apical region has an exposed surface and lies opposite to the basal lamina that separates the epithelium from other tissue.	tmpzr1t_l9r_go_relaxed.owl	apical region of cell													cellular_component											owl:Class	
GO:0014816	biolink:NamedThing	skeletal muscle satellite cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a satellite cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0099562	biolink:NamedThing	maintenance of postsynaptic density structure	A process which maintains the organization and the arrangement of proteins in the presynaptic density.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0048611	biolink:NamedThing	embryonic ectodermal digestive tract development	The process, occurring during the embryonic phase, whose specific outcome is the progression of the ectodermal gut over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl	embryonic ectodermal gut development													biological_process											owl:Class	
GO:0009541	biolink:NamedThing	etioplast prolamellar body	A three dimensional regular lattice found in etioplasts. It is composed of a continuous system of tubules but when exposed to light the symmetrical arrangement is rapidly lost as tubules become pinched off into two dimensional sections of lattice. These for perforated sheets of membrane that move apart, extend and increase, finally establishing the typical granal and intergranal lamellae of the mature chloroplast.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0098559	biolink:NamedThing	cytoplasmic side of early endosome membrane	The side (leaflet) of the early endosome membrane that faces the cytoplasm.	tmpzr1t_l9r_go_relaxed.owl	external side of early endosome membrane|external leaflet of early endosome membrane					In GO, 'external side' still refers to part of the membrane and does not refer to components beyond (outside of) the membrane.								cellular_component											owl:Class	
GO:0031901	biolink:NamedThing	early endosome membrane	The lipid bilayer surrounding an early endosome.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0006685	biolink:NamedThing	sphingomyelin catabolic process	The chemical reactions and pathways resulting in the breakdown of sphingomyelin, N-acyl-4-sphingenyl-1-O-phosphorylcholine.	tmpzr1t_l9r_go_relaxed.owl	sphingomyelin degradation|sphingomyelin breakdown|sphingomyelin catabolism													biological_process											owl:Class	
GO:0044333	biolink:NamedThing	Wnt signaling pathway involved in digestive tract morphogenesis	The series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of the target cell contributing to the generation and the organization of the digestive tract.	tmpzr1t_l9r_go_relaxed.owl	Wnt receptor signaling pathway involved in digestive tract morphogenesis|Wnt receptor signalling pathway involved in digestive tract morphogenesis|Wnt-activated signaling pathway involved in digestive tract morphogenesis							jl	2010-08-20T11:36:23Z					biological_process											owl:Class	
GO:1903730	biolink:NamedThing	regulation of phosphatidate phosphatase activity	Any process that modulates the frequency, rate or extent of phosphatidate phosphatase activity.	tmpzr1t_l9r_go_relaxed.owl	regulation of phosphatidic acid phosphatase activity|regulation of phosphatic acid phosphatase activity|regulation of acid phosphatidyl phosphatase activity|regulation of 3-sn-phosphatidate phosphohydrolase activity|regulation of phosphatic acid phosphohydrolase activity|regulation of phosphatidate phosphohydrolase activity					Any process that modulates the frequency, rate or extent of phosphatidate phosphatase activity		rn	2014-12-11T21:29:55Z					biological_process											owl:Class	
GO:0055103	biolink:NamedThing	ligase regulator activity	Binds to and modulates the activity of a ligase.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0007286	biolink:NamedThing	spermatid development	The process whose specific outcome is the progression of a spermatid over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl	spermiogenesis|spermatid cell development				Wikipedia:Spermiogenesis									biological_process											owl:Class	
GO:0044604	biolink:NamedThing	ABC-type phytochelatin transporter activity	Enables the directed movement of a phytochelatin from one side of a membrane to the other. Phytochelatins are a group of peptides that bind metals (Cd, Zn, Cu, Pb, Hg) in thiolate coordination complexes.	tmpzr1t_l9r_go_relaxed.owl	ABC-type phytochelatin transmembrane transporter activity|cadystin transmembrane transporter activity|ATPase-coupled phytochelatin transmembrane transporter activity|phytochelatin transporter activity|cadystin transmembrane transporter ATPase activity|ATP-dependent phytochelatin transmembrane transporter activity|phytochelatin transmembrane transporter ATPase activity|phytochelatin transmembrane transporter activity|cadystin transporter activity	https://github.com/geneontology/go-ontology/issues/14492						jl	2010-10-25T01:00:17Z			GO:0071992|GO:0071991		molecular_function											owl:Class	
GO:0032825	biolink:NamedThing	positive regulation of natural killer cell differentiation	Any process that activates or increases the frequency, rate or extent of natural killer cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	activation of natural killer cell differentiation|up regulation of natural killer cell differentiation|positive regulation of natural killer cell development|up-regulation of natural killer cell differentiation|stimulation of natural killer cell differentiation|upregulation of natural killer cell differentiation|positive regulation of NK cell differentiation					Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.								biological_process											owl:Class	
GO:1905256	biolink:NamedThing	negative regulation of RNA binding transcription factor activity	Any process that stops, prevents or reduces the frequency, rate or extent of RNA binding transcription factor activity.	tmpzr1t_l9r_go_relaxed.owl	inhibition of RNA binding transcription factor activity|downregulation of RNA binding transcription factor activity|down-regulation of RNA binding transcription factor activity|down regulation of RNA binding transcription factor activity							bf	2016-06-13T11:29:20Z					biological_process											owl:Class	
GO:0035271	biolink:NamedThing	ring gland development	Progression of the ring gland over time, from its formation to a mature structure. The ring gland is a neuroendocrine organ found in higher Dipterans, which is composed of the prothoracic gland, the corpus allatum, and the corpora cardiacum. The ring gland is the site of production and release of ecdysteroids and juvenile hormones.	tmpzr1t_l9r_go_relaxed.owl						See also the fly_anatomy.ontology terms 'ring gland ; FBbt:00001722, 'prothoracic gland ; FBbt:00001724', 'corpus allatum ; FBbt:00005800' and 'corpus cardiacum ; FBbt:00005799.								biological_process											owl:Class	
GO:0016322	biolink:NamedThing	neuron remodeling	The developmentally regulated remodeling of neuronal projections such as pruning to eliminate the extra dendrites and axons projections set up in early stages of nervous system development.	tmpzr1t_l9r_go_relaxed.owl	neuronal remodeling|axon pruning													biological_process											owl:Class	
GO:0043588	biolink:NamedThing	skin development	The process whose specific outcome is the progression of the skin over time, from its formation to the mature structure. The skin is the external membranous integument of an animal. In vertebrates the skin generally consists of two layers, an outer nonsensitive and nonvascular epidermis (cuticle or skarfskin) composed of cells which are constantly growing and multiplying in the deeper, and being thrown off in the superficial layers, as well as an inner vascular dermis (cutis, corium or true skin) composed mostly of connective tissue.	tmpzr1t_l9r_go_relaxed.owl	animal skin development													biological_process											owl:Class	
GO:0002433	biolink:NamedThing	immune response-regulating cell surface receptor signaling pathway involved in phagocytosis	An immune response-regulating cell surface receptor signaling pathway that contributes to the endocytic engulfment of external particulate material by phagocytes.	tmpzr1t_l9r_go_relaxed.owl	phagocytosis triggered by activation of immune response cell surface activating receptor|immune response-regulating cell surface receptor signalling pathway involved in phagocytosis													biological_process											owl:Class	
GO:0006909	biolink:NamedThing	phagocytosis	A vesicle-mediated transport process that results in the engulfment of external particulate material by phagocytes and their delivery to the lysosome. The particles are initially contained within phagocytic vacuoles (phagosomes), which then fuse with primary lysosomes to effect digestion of the particles.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Phagocytosis									biological_process											owl:Class	
GO:0019763	biolink:NamedThing	immunoglobulin receptor activity	Combining with the Fc region of an immunoglobulin protein and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	FC receptor activity											GO:0016489		molecular_function											owl:Class	
GO:0014725	biolink:NamedThing	regulation of extraocular skeletal muscle development	Any process that modulates the frequency, rate or extent of extraocular skeletal muscle development. Extraocular skeletal muscle development is the process whose specific outcome is the progression of the extraocular skeletal muscle over time, from its formation to the mature structure. The extraocular muscle is derived from cranial mesoderm and controls eye movements. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0019889	biolink:NamedThing	pteridine metabolic process	The chemical reactions and pathways involving pteridine, pyrazino(2,3-dipyrimidine), the parent structure of pterins and the pteroyl group.	tmpzr1t_l9r_go_relaxed.owl	pteridine metabolism													biological_process											owl:Class	
GO:0010240	biolink:NamedThing	plastid pyruvate dehydrogenase complex	Complex that carries out the oxidative decarboxylation of pyruvate to form acetyl-CoA; comprises subunits possessing three catalytic activities: pyruvate dehydrogenase (E1), dihydrolipoamide S-acetyltransferase (E2), and dihydrolipoamide dehydrogenase (E3). This complex is found in plant plastids and is distinct from the one found in mitochondria.	tmpzr1t_l9r_go_relaxed.owl	dehydrogenase complex													cellular_component											owl:Class	
GO:0120321	biolink:NamedThing	nuclear envelope adjacent to nuclear pore complex	The region of the nuclear envelope situated in close proximity to a nuclear pore complex.	tmpzr1t_l9r_go_relaxed.owl	nuclear envelope periphery of the nuclear pore complex|associated with the nuclear pore|nuclear envelope adjacent to NPC	https://github.com/geneontology/go-ontology/issues/21774						krc	2021-07-07T20:30:21Z					cellular_component											owl:Class	
GO:0060854	biolink:NamedThing	branching involved in lymph vessel morphogenesis	The process of the coordinated growth and sprouting of lymph vessels giving rise to the organized lymphatic system.	tmpzr1t_l9r_go_relaxed.owl	patterning of lymph vessels							dph	2009-08-12T12:00:48Z					biological_process											owl:Class	
GO:1902805	biolink:NamedThing	positive regulation of synaptic vesicle transport	Any process that activates or increases the frequency, rate or extent of synaptic vesicle transport.	tmpzr1t_l9r_go_relaxed.owl	up regulation of synaptic vesicle transport|positive regulation of synaptic vesicle fusion|up-regulation of synaptic vesicle fission|up regulation of synaptic vesicle fusion|upregulation of synaptic vesicle fission|up regulation of synaptic vesicle fission|upregulation of synaptic vesicle transport|upregulation of synaptic vesicle fusion|up-regulation of synaptic vesicle transport|activation of synaptic vesicle fission|activation of synaptic vesicle transport|positive regulation of synaptic vesicle fission|up-regulation of synaptic vesicle fusion|activation of synaptic vesicle fusion							kmv	2014-03-25T14:56:46Z					biological_process											owl:Class	
GO:0048489	biolink:NamedThing	synaptic vesicle transport	The directed movement of synaptic vesicles.	tmpzr1t_l9r_go_relaxed.owl	synaptic vesicle trafficking|synaptic vesicle fission|synaptic vesicle fusion											GO:0016181		biological_process											owl:Class	
GO:0003391	biolink:NamedThing	amphid sensory organ dendrite retrograde extension	The progression of an amphid sensory organ's neuronal dendrite over time by the attachment of a part of the cell to an anchor and the subsequent migration of the cell body away from the anchor point.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-12-09T09:28:27Z					biological_process											owl:Class	
GO:0003388	biolink:NamedThing	neuron development involved in amphid sensory organ development	The process whose specific outcome is the progression of a neuron over time, that contributes to the development of the amphid sensory organ.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-12-09T09:18:06Z					biological_process											owl:Class	
GO:0007259	biolink:NamedThing	receptor signaling pathway via JAK-STAT	Any process in which STAT proteins (Signal Transducers and Activators of Transcription) and JAK (Janus Activated Kinase) proteins convey a signal to trigger a change in the activity or state of a cell. The receptor signaling pathway via JAK-STAT begins with activation of a receptor and proceeeds through STAT protein activation by members of the JAK family of tyrosine kinases. STAT proteins dimerize and subsequently translocate to the nucleus. The pathway ends with regulation of target gene expression by STAT proteins.	tmpzr1t_l9r_go_relaxed.owl	JAK-STAT cascade|JAK-STAT signal transduction				Wikipedia:JAK-STAT_signaling_pathway									biological_process											owl:Class	
GO:0030902	biolink:NamedThing	hindbrain development	The process whose specific outcome is the progression of the hindbrain over time, from its formation to the mature structure. The hindbrain is the posterior of the three primary divisions of the developing chordate brain, or the corresponding part of the adult brain (in vertebrates, includes the cerebellum, pons, and medulla oblongata and controls the autonomic functions and equilibrium).	tmpzr1t_l9r_go_relaxed.owl	rhombencephalon development													biological_process											owl:Class	
GO:0002077	biolink:NamedThing	acrosome matrix dispersal	The proteolytic digestion of components in the acrosomal matrix that occurs as part of the acrosome reaction. The process can occur either in the cumulus oophorous facilitating the penetration of it by the sperm, or at the zona pellucida allowing the sperm to reach the plasma membrane of the egg where the inner acrosomal membrane of the sperm can interact with the egg plasma membrane.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0017109	biolink:NamedThing	glutamate-cysteine ligase complex	An enzyme complex that catalyzes the ligation of glutamate to cysteine, forming glutamylcysteine.	tmpzr1t_l9r_go_relaxed.owl	gamma-glutamylcysteine synthetase complex													cellular_component											owl:Class	
GO:0005778	biolink:NamedThing	peroxisomal membrane	The lipid bilayer surrounding a peroxisome.	tmpzr1t_l9r_go_relaxed.owl	peroxisome membrane													cellular_component											owl:Class	
GO:0021519	biolink:NamedThing	spinal cord association neuron specification	The process in which a cell becomes capable of differentiating autonomously into an association neuron in an environment that is neutral with respect to the developmental pathway.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0032607	biolink:NamedThing	interferon-alpha production	The appearance of interferon-alpha due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	tmpzr1t_l9r_go_relaxed.owl	IFN-alpha production|interferon-alpha secretion|IFNA production|interferon-alpha biosynthetic process					Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.						GO:0045349|GO:0072642		biological_process											owl:Class	
GO:1902159	biolink:NamedThing	regulation of cyclic nucleotide-gated ion channel activity	Any process that modulates the frequency, rate or extent of cyclic nucleotide-gated ion channel activity.	tmpzr1t_l9r_go_relaxed.owl	regulation of cyclic nucleotide-activated ion channel activity|regulation of cyclic nucleotide gated ion channel activity|regulation of cyclic nucleotide activated ion channel activity							sl	2013-05-21T19:24:30Z					biological_process											owl:Class	
GO:0043855	biolink:NamedThing	cyclic nucleotide-gated ion channel activity	Enables the transmembrane transfer of an ion by a channel that opens when a cyclic nucleotide has been bound by the channel complex or one of its constituent parts.	tmpzr1t_l9r_go_relaxed.owl	cyclic nucleotide activated ion channel activity|cyclic nucleotide-activated ion channel activity|cyclic nucleotide gated ion channel activity													molecular_function											owl:Class	
GO:0021580	biolink:NamedThing	medulla oblongata formation	The process that gives rise to the medulla oblongata. This process pertains to the initial formation of a structure from unspecified parts. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate.	tmpzr1t_l9r_go_relaxed.owl	myelencephalon formation|medulla biosynthesis|medulla formation|myelencephalon biosynthesis													biological_process											owl:Class	
GO:0043709	biolink:NamedThing	cell adhesion involved in single-species biofilm formation	The attachment of a cell to a solid substrate, via cell adhesion molecules, during the formation of a biofilm composed of microorganisms of the same species.	tmpzr1t_l9r_go_relaxed.owl	cell adhesion during single-species biofilm formation													biological_process											owl:Class	
GO:0019284	biolink:NamedThing	L-methionine salvage from S-adenosylmethionine	The chemical reactions and pathways resulting in the formation of L-methionine from S-adenosylmethionine.	tmpzr1t_l9r_go_relaxed.owl	L-methionine synthesis from S-adenosylmethionine|L-methionine formation from S-adenosylmethionine													biological_process											owl:Class	
GO:0070985	biolink:NamedThing	transcription factor TFIIK complex	A transcription factor complex that forms part of the holo TFIIH complex. In Saccharomyces/human, TFIIK contains Ccl1p/Cyclin H, Tfb3p/MAT1 and Kin28p/CDK7.	tmpzr1t_l9r_go_relaxed.owl	Mcs6/Mcs2/Pmh1 complex|cyclin H-CDK7 complex|TFIIK complex							mah	2009-10-27T04:19:37Z					cellular_component											owl:Class	
GO:0005675	biolink:NamedThing	transcription factor TFIIH holo complex	A complex that is capable of kinase activity directed towards the C-terminal Domain (CTD) of the largest subunit of RNA polymerase II and is essential for initiation at RNA polymerase II promoters in vitro. It is composed of  the core TFIIH complex and the TFIIK complex.	tmpzr1t_l9r_go_relaxed.owl	holo TFIIH complex													cellular_component											owl:Class	
GO:0006286	biolink:NamedThing	base-excision repair, base-free sugar-phosphate removal	Excision of the sugar phosphate residue at an AP site, i.e. a deoxyribose sugar with a missing base, by a phosphodiesterase enzyme.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1900566	biolink:NamedThing	chanoclavine-I biosynthetic process	The chemical reactions and pathways resulting in the formation of chanoclavine-I.	tmpzr1t_l9r_go_relaxed.owl	chanoclavine-I anabolism|chanoclavine-I formation|chanoclavine-I biosynthesis|chanoclavine-I synthesis							di	2012-05-15T06:30:55Z					biological_process											owl:Class	
GO:0070253	biolink:NamedThing	somatostatin secretion	The regulated release of somatostatin from secretory granules in the D cells of the pancreas.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0009333	biolink:NamedThing	cysteine synthase complex	Cysteine synthase is a multienzyme complex made up, in E. coli, of the heteromeric hexamer serine acetyltransferase and the homodimer O-acetylserine (thiol)-lyase A.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:1990732	biolink:NamedThing	pyrenoid	A non-membrane-bounded organelle found within the chloroplasts of algae and hornworts; responsible for carbon dioxide fixation.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Pyrenoid			pr	2015-04-24T12:44:52Z					cellular_component											owl:Class	
GO:0021893	biolink:NamedThing	cerebral cortex GABAergic interneuron fate commitment	The process in which the developmental fate of a neuroblast becomes restricted such that it will develop into a GABAergic interneuron residing in the cerebral cortex.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0070078	biolink:NamedThing	histone H3-R2 demethylation	The modification of histone H3 by the removal of a methyl group from arginine at position 2 of the histone.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1900060	biolink:NamedThing	negative regulation of ceramide biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of a ceramide biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of ceramide anabolism|downregulation of ceramide formation|down-regulation of ceramide synthesis|negative regulation of ceramide biosynthesis|downregulation of ceramide biosynthetic process|down regulation of ceramide anabolism|negative regulation of ceramide synthesis|inhibition of ceramide biosynthesis|down regulation of ceramide biosynthetic process|negative regulation of ceramide formation|inhibition of ceramide formation|down-regulation of ceramide formation|down regulation of ceramide biosynthesis|downregulation of ceramide biosynthesis|down-regulation of ceramide biosynthetic process|downregulation of ceramide synthesis|downregulation of ceramide anabolism|inhibition of ceramide synthesis|down-regulation of ceramide anabolism|down-regulation of ceramide biosynthesis|inhibition of ceramide biosynthetic process|inhibition of ceramide anabolism|down regulation of ceramide synthesis|down regulation of ceramide formation							dph	2012-01-25T03:18:07Z					biological_process											owl:Class	
GO:1900104	biolink:NamedThing	regulation of hyaluranon cable assembly	Any process that modulates the frequency, rate or extent of hyaluranon cable assembly.	tmpzr1t_l9r_go_relaxed.owl	regulation of HA cable assembly							yaf	2012-02-16T01:00:41Z					biological_process											owl:Class	
GO:0036118	biolink:NamedThing	hyaluranon cable assembly	A process that results in the aggregation, arrangement and bonding together of a hyaluranon cable, a cable structure, surrounding some cell types (e.g. proximal or bronchial tubular epithelial cells), and composed of hyaluranon (HA), a ubiquitous connective tissue glycosaminoglycan.	tmpzr1t_l9r_go_relaxed.owl	HA cable assembly							bf	2012-02-16T11:06:58Z					biological_process											owl:Class	
GO:0005758	biolink:NamedThing	mitochondrial intermembrane space	The region between the inner and outer lipid bilayers of the mitochondrial envelope.	tmpzr1t_l9r_go_relaxed.owl	mitochondrial membrane lumen|mitochondrial envelope lumen				NIF_Subcellular:sao118944228							GO:0031971		cellular_component											owl:Class	
GO:1903899	biolink:NamedThing	positive regulation of PERK-mediated unfolded protein response	Any process that activates or increases the frequency, rate or extent of the PERK-mediated unfolded protein response.	tmpzr1t_l9r_go_relaxed.owl	activation of PKR-like ER kinase signal transduction|upregulation of PERK signaling in response to endoplasmic reticulum stress|up regulation of PERK signaling in response to endoplasmic reticulum stress|positive regulation of endoplasmic reticulum unfolded protein response; PERK signaling|up regulation of PERK-mediated unfolded protein response|upregulation of endoplasmic reticulum unfolded protein response; PERK signaling|activation of PERK-mediated unfolded protein response|upregulation of PERK branch of UPR|upregulation of PERK-mediated unfolded protein response|positive regulation of EIF2AK3-mediated unfolded protein response|up-regulation of PERK signaling in response to endoplasmic reticulum stress|upregulation of UPR signaling by PERK stress sensor|up regulation of endoplasmic reticulum unfolded protein response; PERK signaling|up-regulation of PERK-mediated unfolded protein response|activation of endoplasmic reticulum unfolded protein response; PERK signaling|up-regulation of UPR signaling by PERK stress sensor|activation of PERK signaling in response to endoplasmic reticulum stress|up-regulation of endoplasmic reticulum unfolded protein response; PERK signaling|positive regulation of UPR signaling by PERK stress sensor|upregulation of PKR-like ER kinase signal transduction|up regulation of PERK branch of UPR|positive regulation of PERK branch of UPR|positive regulation of PKR-like ER kinase signal transduction|up regulation of UPR signaling by PERK stress sensor|positive regulation of PERK signaling in response to endoplasmic reticulum stress|up regulation of PKR-like ER kinase signal transduction|activation of PERK branch of UPR|activation of UPR signaling by PERK stress sensor|up-regulation of PERK branch of UPR|up-regulation of PKR-like ER kinase signal transduction							bf	2015-02-09T10:18:32Z					biological_process											owl:Class	
GO:1905706	biolink:NamedThing	regulation of mitochondrial ATP synthesis coupled proton transport	Any process that modulates the frequency, rate or extent of mitochondrial ATP synthesis coupled proton transport.	tmpzr1t_l9r_go_relaxed.owl								vw	2016-11-17T14:07:33Z					biological_process											owl:Class	
GO:0042776	biolink:NamedThing	mitochondrial ATP synthesis coupled proton transport	The transport of protons across a mitochondrial membrane to generate an electrochemical gradient (proton-motive force) that powers ATP synthesis.	tmpzr1t_l9r_go_relaxed.owl	mitochondrial proton transport													biological_process											owl:Class	
GO:0062244	biolink:NamedThing	double membrane vesicle viral factory lumen	The volume surrounded by the inner membrane of a double membrane vesicle viral factory.	tmpzr1t_l9r_go_relaxed.owl	lumen of double membrane vesicle viral factory							dph	2020-04-20T20:53:30Z					cellular_component											owl:Class	
GO:0039718	biolink:NamedThing	double membrane vesicle viral factory	A cytoplasmic viral factory that consists of a double-membrane bound vesicle. Has a diameter of 200-300nm and is derived from the endoplasmic reticulum or Golgi apparatus. Produced by Picornaviridae, Nidovirales, Arteriviridae and Coronaviridae.	tmpzr1t_l9r_go_relaxed.owl	DMV viral factory							bf	2013-12-19T15:31:22Z					cellular_component											owl:Class	
GO:0060631	biolink:NamedThing	regulation of meiosis I	Any process that modulates the rate, frequency, or extent of meiosis I, a cell cycle process comprising the steps by which a cell progresses through the first phase of meiosis, in which cells divide and homologous chromosomes are paired and segregated from each other, producing two daughter cells.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-05-18T02:55:19Z					biological_process											owl:Class	
GO:0007127	biolink:NamedThing	meiosis I	The first meiotic nuclear division in which homologous chromosomes are paired and segregated from each other, producing two haploid daughter nuclei.	tmpzr1t_l9r_go_relaxed.owl	meiosis I nuclear division				Wikipedia:Meiosis#Meiosis_I									biological_process											owl:Class	
GO:0038198	biolink:NamedThing	auxin receptor activity	Combining with auxin and transmitting the signal in the cell to initiate a change in cell activity. Auxin is a plant hormone (phytohormone).	tmpzr1t_l9r_go_relaxed.owl								bf	2013-12-05T15:47:42Z					molecular_function											owl:Class	
GO:0010011	biolink:NamedThing	auxin binding	Binding to auxin, a plant hormone that regulates aspects of plant growth.	tmpzr1t_l9r_go_relaxed.owl	auxin receptor													molecular_function											owl:Class	
GO:0005905	biolink:NamedThing	clathrin-coated pit	A part of the endomembrane system in the form of an invagination of a membrane upon which a clathrin coat forms, and that can be converted by vesicle budding into a clathrin-coated vesicle. Coated pits form on the plasma membrane, where they are involved in receptor-mediated selective transport of many proteins and other macromolecules across the cell membrane, in the trans-Golgi network, and on some endosomes.	tmpzr1t_l9r_go_relaxed.owl	coated pit				NIF_Subcellular:sao1969557946									cellular_component											owl:Class	
GO:0060953	biolink:NamedThing	cardiac glial cell fate commitment	The commitment of cells to cardiac glial cell fates and their capacity to differentiate into cardiac glial cells.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-09-29T03:11:23Z					biological_process											owl:Class	
GO:0060950	biolink:NamedThing	cardiac glial cell differentiation	The process in which a relatively unspecialized cell acquires the specialized features of a glial cell of the heart.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-09-29T03:06:37Z					biological_process											owl:Class	
GO:1903204	biolink:NamedThing	negative regulation of oxidative stress-induced neuron death	Any process that stops, prevents or reduces the frequency, rate or extent of oxidative stress-induced neuron death.	tmpzr1t_l9r_go_relaxed.owl	downregulation of neuron death in response to oxidative stress|down-regulation of neuron death in response to oxidative stress|inhibition of oxidative stress-induced neuron death|inhibition of neuron death in response to oxidative stress|down regulation of oxidative stress-induced neuron death|down regulation of neuronal cell death in response to oxidative stress|inhibition of neuronal cell death in response to oxidative stress|down regulation of neuron death in response to oxidative stress|downregulation of neuronal cell death in response to oxidative stress|down-regulation of oxidative stress-induced neuron death|neuronal protection under oxidative stress|negative regulation of neuronal cell death in response to oxidative stress|down-regulation of neuronal cell death in response to oxidative stress|downregulation of oxidative stress-induced neuron death|neuroprotection against oxidative stress							bf	2014-07-21T16:17:36Z					biological_process											owl:Class	
GO:0061709	biolink:NamedThing	reticulophagy	The selective autohagy process in which parts of the endoplasmic reticulum are loaded into autophagosomes, delivered to the vacuole, and degraded in response to changing cellular conditions.	tmpzr1t_l9r_go_relaxed.owl	ER-phagy|endoplasmic reticulum autophagy|autophagy of the endoplasmic reticulum|endoplasmic reticulum degradation|ER degradation|ER autophagy|autophagy of the ER							dph	2015-06-18T15:15:48Z			GO:1990766		biological_process											owl:Class	
GO:1905692	biolink:NamedThing	endoplasmic reticulum disassembly	The disaggregation of an endoplasmic reticulum into its constituent components.	tmpzr1t_l9r_go_relaxed.owl	ER disassembly							pr	2016-11-14T13:39:14Z					biological_process											owl:Class	
GO:1902870	biolink:NamedThing	negative regulation of amacrine cell differentiation	Any process that stops, prevents or reduces the frequency, rate or extent of amacrine cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	down regulation of amacrine cell differentiation|downregulation of amacrine neuron differentiation|inhibition of amacrine neuron differentiation|down-regulation of amacrine neuron differentiation|negative regulation of amacrine neuron differentiation|downregulation of amacrine cell differentiation|inhibition of amacrine cell differentiation|down regulation of amacrine neuron differentiation|down-regulation of amacrine cell differentiation							mr	2014-04-03T15:24:40Z					biological_process											owl:Class	
GO:0035881	biolink:NamedThing	amacrine cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of an amacrine cell, an interneuron generated in the inner nuclear layer (INL) of the vertebrate retina. Amacrine cells integrate, modulate, and interpose a temporal domain in the visual message presented to the retinal ganglion cells, with which they synapse in the inner plexiform layer. Amacrine cells lack large axons.	tmpzr1t_l9r_go_relaxed.owl	amacrine neuron differentiation							bf	2011-06-06T11:32:50Z					biological_process											owl:Class	
GO:0031308	biolink:NamedThing	intrinsic component of nuclear outer membrane	The component of the nuclear outer membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.	tmpzr1t_l9r_go_relaxed.owl	intrinsic to nuclear outer membrane													cellular_component											owl:Class	
GO:0007396	biolink:NamedThing	suture of dorsal opening	Closure of the dorsal hole. Filopodia extending from each leading edge interdigitate at the dorsal midline and appear to prime the formation of adherens junctions between the two rows of leading edge cells. Newly formed septate junctions are also used to seal the dorsal hole.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0031269	biolink:NamedThing	pseudopodium assembly	The assembly of a pseudopodium by rearrangement of the actin cytoskeleton and overlying membrane.	tmpzr1t_l9r_go_relaxed.owl	pseudopodium formation|pseudopodium extension													biological_process											owl:Class	
GO:0072276	biolink:NamedThing	metanephric glomerulus vasculature morphogenesis	The process in which the anatomical structures of the metanephric glomerulus vasculature are generated and organized. The metanephric glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the metanephric glomerulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-04-01T02:47:32Z					biological_process											owl:Class	
GO:0043046	biolink:NamedThing	DNA methylation involved in gamete generation	The covalent transfer of a methyl group to C-5 of cytosine that contributes to the establishment of DNA methylation patterns in the gamete.	tmpzr1t_l9r_go_relaxed.owl	de novo DNA methylation													biological_process											owl:Class	
GO:1901717	biolink:NamedThing	positive regulation of gamma-aminobutyric acid catabolic process	Any process that activates or increases the frequency, rate or extent of gamma-aminobutyric acid catabolic process.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of GABA catabolic process|upregulation of 4-aminobutanoate catabolism|up regulation of 4-aminobutanoate catabolism|up regulation of gamma-aminobutyric acid breakdown|up regulation of GABA catabolic process|activation of 4-aminobutanoate catabolism|activation of gamma-aminobutyric acid catabolism|up-regulation of gamma-aminobutyric acid catabolic process|upregulation of gamma-aminobutyric acid breakdown|up-regulation of gamma-aminobutyric acid breakdown|up regulation of GABA catabolism|positive regulation of GABA catabolism|activation of gamma-aminobutyric acid degradation|positive regulation of gamma-aminobutyric acid breakdown|positive regulation of gamma-aminobutyric acid degradation|up-regulation of 4-aminobutyrate catabolic process|up regulation of 4-aminobutyrate catabolic process|upregulation of 4-aminobutyrate catabolism|activation of GABA catabolic process|upregulation of gamma-aminobutyric acid catabolic process|up regulation of 4-aminobutanoate catabolic process|activation of 4-aminobutyrate catabolic process|positive regulation of 4-aminobutanoate catabolic process|up-regulation of GABA catabolism|activation of 4-aminobutanoate catabolic process|activation of GABA catabolism|positive regulation of 4-aminobutanoate catabolism|upregulation of GABA catabolism|up-regulation of gamma-aminobutyric acid degradation|activation of 4-aminobutyrate catabolism|up-regulation of 4-aminobutyrate catabolism|activation of gamma-aminobutyric acid breakdown|positive regulation of 4-aminobutyrate catabolic process|up regulation of 4-aminobutyrate catabolism|up-regulation of 4-aminobutanoate catabolic process|up regulation of gamma-aminobutyric acid catabolism|positive regulation of gamma-aminobutyric acid catabolism|upregulation of gamma-aminobutyric acid catabolism|upregulation of 4-aminobutyrate catabolic process|up-regulation of GABA catabolic process|up regulation of gamma-aminobutyric acid degradation|up-regulation of gamma-aminobutyric acid catabolism|positive regulation of 4-aminobutyrate catabolism|upregulation of gamma-aminobutyric acid degradation|upregulation of GABA catabolic process|activation of gamma-aminobutyric acid catabolic process|up-regulation of 4-aminobutanoate catabolism|up regulation of gamma-aminobutyric acid catabolic process|upregulation of 4-aminobutanoate catabolic process							mcc	2012-12-19T16:13:36Z					biological_process											owl:Class	
GO:0009450	biolink:NamedThing	gamma-aminobutyric acid catabolic process	The chemical reactions and pathways resulting in the breakdown of gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms.	tmpzr1t_l9r_go_relaxed.owl	gamma-aminobutyric acid catabolism|GABA catabolism|4-aminobutyrate catabolism|4-aminobutanoate catabolism|gamma-aminobutyric acid breakdown|4-aminobutyrate catabolic process|gamma-aminobutyric acid degradation|4-aminobutanoate catabolic process|GABA catabolic process				MetaCyc:4AMINOBUTMETAB-PWY	See also the biological process term 'neurotransmitter catabolic process ; GO:0042135'.								biological_process											owl:Class	
GO:0044175	biolink:NamedThing	host cell endosome membrane	The lipid bilayer surrounding a host cell endosome.	tmpzr1t_l9r_go_relaxed.owl	host endosome membrane							jl	2009-09-04T03:04:04Z					cellular_component											owl:Class	
GO:0140010	biolink:NamedThing	D-aspartate transmembrane transporter activity	Enables the transfer of D-aspartate from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl								pg	2017-03-13T11:15:15Z					molecular_function											owl:Class	
GO:0033017	biolink:NamedThing	sarcoplasmic reticulum membrane	The lipid bilayer surrounding the sarcoplasmic reticulum.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0070459	biolink:NamedThing	prolactin secretion	The regulated release of prolactin, a peptide hormone that stimulates lactation, from secretory granules in the anterior pituitary.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0061244	biolink:NamedThing	mesonephric S-shaped body morphogenesis	The process in which the mesonephric S-shaped body is generated and organized. The mesonephric S-shaped body is the successor of the mesonephric comma-shaped body that contributes to the morphogenesis of a nephron in the mesonephros.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-08-19T03:23:55Z					biological_process											owl:Class	
GO:0038177	biolink:NamedThing	death receptor agonist activity	Interacting with a death receptor such that the proportion of death receptors in an active form is increased. Ligand binding to a death receptor often induces a conformational change to activate the receptor.	tmpzr1t_l9r_go_relaxed.owl	death receptor activator activity							bf	2012-09-20T12:52:00Z					molecular_function											owl:Class	
GO:0005123	biolink:NamedThing	death receptor binding	Binding to a member of the death receptor (DR) family. The DR family falls within the tumor necrosis factor receptor superfamily and is characterized by a cytoplasmic region of ~80 residues termed the death domain (DD).	tmpzr1t_l9r_go_relaxed.owl	DR binding|TRAIL binding|death receptor adaptor protein activity|KILLER binding|APO binding|FAS binding|EDAR binding|TNFR1 binding|NGFR binding|death receptor-associated factor activity|death receptor interacting protein activity|death receptor ligand													molecular_function											owl:Class	
GO:0080060	biolink:NamedThing	integument development	The process whose specific outcome is the progression of the integument over time, from its formation to the mature structure. Integument is one of the layers of tissue that usually covers the ovule, enveloping the nucellus and forming the micropyle at the apex.	tmpzr1t_l9r_go_relaxed.owl								dhl	2009-04-13T02:58:07Z					biological_process											owl:Class	
GO:0048574	biolink:NamedThing	long-day photoperiodism, flowering	A change from the vegetative to the reproductive phase as a result of detection of, or exposure to, a period of light that exceeds the critical day length. The critical day length varies between species. Although the term is long-day is used, most species actually respond to the duration of the night, so that the response will occur when a period of darkness falls short of the number of hours defined by 24 minus the critical day length.	tmpzr1t_l9r_go_relaxed.owl	response to short-night, flowering|response to long-day, flowering|long-day photoperiodic control of inflorescence development|long-day photoperiodic control of flowering|long-day photoperiodic control of flowering time|short-night photoperiodism, flowering													biological_process											owl:Class	
GO:2000035	biolink:NamedThing	regulation of stem cell division	Any process that modulates the frequency, rate or extent of stem cell division.	tmpzr1t_l9r_go_relaxed.owl	regulation of stem cell renewal							tb	2010-08-05T11:34:53Z					biological_process											owl:Class	
GO:0061798	biolink:NamedThing	GTP 3',8'-cyclase activity	Catalysis of the reaction: GTP=(8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.	tmpzr1t_l9r_go_relaxed.owl					RHEA:49576|MetaCyc:RXN-8340|EC:4.1.99.22			dph	2016-10-06T14:26:11Z					molecular_function											owl:Class	
GO:0002510	biolink:NamedThing	central B cell tolerance induction	Tolerance induction of B cells in the bone marrow.	tmpzr1t_l9r_go_relaxed.owl	central B-cell tolerance induction|central B lymphocyte tolerance induction|central B-lymphocyte tolerance induction													biological_process											owl:Class	
GO:0072593	biolink:NamedThing	reactive oxygen species metabolic process	The chemical reactions and pathways involving a reactive oxygen species, any molecules or ions formed by the incomplete one-electron reduction of oxygen. They contribute to the microbicidal activity of phagocytes, regulation of signal transduction and gene expression, and the oxidative damage to biopolymers.	tmpzr1t_l9r_go_relaxed.owl	ROS metabolic process|reactive oxygen species metabolism							mah	2011-02-11T10:50:06Z					biological_process											owl:Class	
GO:0002540	biolink:NamedThing	leukotriene production involved in inflammatory response	The synthesis or release of any leukotriene following a stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels.	tmpzr1t_l9r_go_relaxed.owl	leukotriene production involved in acute inflammatory response													biological_process											owl:Class	
GO:1900681	biolink:NamedThing	octadecene metabolic process	The chemical reactions and pathways involving octadecene.	tmpzr1t_l9r_go_relaxed.owl	octadecene metabolism							tt	2012-05-22T04:28:28Z					biological_process											owl:Class	
GO:0061298	biolink:NamedThing	retina vasculature development in camera-type eye	The process whose specific outcome is the progression of the vasculature of the retina over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl	retinal vasculature development							dph	2010-09-06T03:27:06Z					biological_process											owl:Class	
GO:1902010	biolink:NamedThing	negative regulation of translation in response to endoplasmic reticulum stress	Any process that stops, prevents, or reduces the frequency, rate or extent of translation as a result of endoplasmic reticulum stress.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of protein synthesis involved in ER stress response|protein biosynthetic process inhibitor activity involved in response to ER stress|negative regulation of protein biosynthesis involved in response to ER stress|downregulation of protein biosynthetic process involved in ER stress response|protein biosynthesis inhibitor activity involved in ER stress response|down-regulation of protein biosynthetic process involved in ER stress response|negative regulation of protein biosynthesis involved in ER stress response|down-regulation of protein biosynthetic process involved in response to ER stress|inhibition of protein biosynthetic process involved in response to endoplasmic reticulum stress|negative regulation of protein biosynthetic process involved in response to endoplasmic reticulum stress|negative regulation of translation involved in ER stress response|negative regulation of protein anabolism involved in response to endoplasmic reticulum stress|negative regulation of translation involved in response to ER stress|down regulation of protein biosynthetic process involved in response to ER stress|negative regulation of protein synthesis involved in response to endoplasmic reticulum stress|negative regulation of protein formation involved in response to endoplasmic reticulum stress|down regulation of protein biosynthetic process involved in response to endoplasmic reticulum stress|downregulation of protein biosynthetic process involved in response to endoplasmic reticulum stress|protein biosynthesis inhibitor activity involved in response to ER stress|negative regulation of protein biosynthetic process involved in ER stress response|protein biosynthetic process inhibitor activity involved in ER stress response|down-regulation of protein biosynthetic process involved in response to endoplasmic reticulum stress|negative regulation of protein formation involved in response to ER stress|protein biosynthesis inhibitor activity involved in response to endoplasmic reticulum stress|inhibition of protein biosynthetic process involved in response to ER stress|negative regulation of protein synthesis involved in response to ER stress|downregulation of protein biosynthetic process involved in response to ER stress|negative regulation of protein formation involved in ER stress response|inhibition of protein biosynthetic process involved in ER stress response|negative regulation of protein biosynthesis involved in response to endoplasmic reticulum stress|negative regulation of protein anabolism involved in ER stress response|protein biosynthetic process inhibitor activity involved in response to endoplasmic reticulum stress|negative regulation of protein biosynthetic process involved in response to ER stress|negative regulation of protein anabolism involved in response to ER stress|down regulation of protein biosynthetic process involved in ER stress response							dph	2013-03-22T13:43:26Z					biological_process											owl:Class	
GO:0007420	biolink:NamedThing	brain development	The process whose specific outcome is the progression of the brain over time, from its formation to the mature structure. Brain development begins with patterning events in the neural tube and ends with the mature structure that is the center of thought and emotion. The brain is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.).	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0033005	biolink:NamedThing	positive regulation of mast cell activation	Any process that activates or increases the frequency, rate, or extent of mast cell activation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1905478	biolink:NamedThing	regulation of glutamate-ammonia ligase activity	Any process that modulates the frequency, rate or extent of glutamate-ammonia ligase activity.	tmpzr1t_l9r_go_relaxed.owl	regulation of glutamine synthetase activity|regulation of L-glutamine synthetase activity|regulation of L-glutamate:ammonia ligase (ADP-forming)|regulation of glutamylhydroxamic synthetase activity							pga	2016-09-22T09:58:34Z					biological_process											owl:Class	
GO:0004356	biolink:NamedThing	glutamate-ammonia ligase activity	Catalysis of the reaction: L-glutamate + ATP + NH(3) = L-glutamine + ADP + 2 H(+) + phosphate.	tmpzr1t_l9r_go_relaxed.owl	glutamylhydroxamic synthetase activity|L-glutamate:ammonia ligase (ADP-forming)|L-glutamine synthetase activity|glutamine synthetase activity				EC:6.3.1.2|Reactome:R-HSA-70606|MetaCyc:GLUTAMINESYN-RXN|RHEA:16169|KEGG_REACTION:R00253									molecular_function											owl:Class	
GO:1900851	biolink:NamedThing	positive regulation of pseurotin A biosynthetic process	Any process that activates or increases the frequency, rate or extent of pseurotin A biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	upregulation of pseurotin A biosynthetic process|up regulation of pseurotin A biosynthetic process|up-regulation of pseurotin A biosynthetic process							di	2012-06-07T09:45:56Z					biological_process											owl:Class	
GO:0055123	biolink:NamedThing	digestive system development	The process whose specific outcome is the progression of the digestive system over time, from its formation to the mature structure. The digestive system is the entire structure in which digestion takes place. Digestion is all of the physical, chemical, and biochemical processes carried out by multicellular organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0038002	biolink:NamedThing	endocrine signaling	The transfer of information from one cell to another, where an endocrine hormone is transported from the signal-producing cell to the receiving cell via the circulatory system (via blood, lymph or cerebrospinal fluid). The signaling cell and the receiving cell are often distant to each other.	tmpzr1t_l9r_go_relaxed.owl	endocrine signalling					This term should be used with caution, and only used when the signaling between cells has been clearly distinguished from paracrine signaling.		bf	2011-02-25T02:12:19Z					biological_process											owl:Class	
GO:0000112	biolink:NamedThing	nucleotide-excision repair factor 3 complex	One of several protein complexes involved in nucleotide-excision repair; possesses endodeoxynuclease and DNA helicase activities. In S. cerevisiae, it is composed of Rad2p and the core TFIIH-Ssl2p complex (core TFIIH is composed of Rad3p, Tfb1p, Tfb2p, Ssl1p, Tfb4p and Tfb5p. Note that Ssl2p is also called Rad25p).	tmpzr1t_l9r_go_relaxed.owl	NEF3 complex					Note that process and function information are included in the term and definition for the purpose of describing and distinguishing the complex.								cellular_component											owl:Class	
GO:0010849	biolink:NamedThing	regulation of proton-transporting ATPase activity, rotational mechanism	Any process that modulates the rate of ATP hydrolysis by an ATPase. Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out), by a rotational mechanism.	tmpzr1t_l9r_go_relaxed.owl	regulation of V-type ATPase activity|regulation of hydrogen ion transporting ATPase activity, rotational mechanism													biological_process											owl:Class	
GO:0002543	biolink:NamedThing	activation of blood coagulation via clotting cascade	Any process that initiates the clotting cascade of blood coagulation, a cascade of plasma enzymes that is triggered following damage to blood vessels, leading to formation of a clot.	tmpzr1t_l9r_go_relaxed.owl	activation of clotting cascade													biological_process											owl:Class	
GO:0002526	biolink:NamedThing	acute inflammatory response	Inflammation which comprises a rapid, short-lived, relatively uniform response to acute injury or antigenic challenge and is characterized by accumulations of fluid, plasma proteins, and granulocytic leukocytes. An acute inflammatory response occurs within a matter of minutes or hours, and either resolves within a few days or becomes a chronic inflammatory response.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0003882	biolink:NamedThing	CDP-diacylglycerol-serine O-phosphatidyltransferase activity	Catalysis of the reaction: CDP-diacylglycerol + L-serine = CMP + O-sn-phosphatidyl-L-serine.	tmpzr1t_l9r_go_relaxed.owl	phosphatidylserine synthetase activity|PS synthase activity|CDPdiglyceride-serine O-phosphatidyltransferase activity|CDP-diacylglycerol-L-serine O-phosphatidyltransferase activity|CDP-diacylglycerol:L-serine 3-O-phosphatidyltransferase activity|cytidine 5'-diphospho-1,2-diacyl-sn-glycerol:L-serine O-phosphatidyltransferase activity|serine exchange enzyme|phosphatidylserine synthase activity|CDP-diglycerine-serine O-phosphatidyltransferase activity|CDPdiacylglycerol-serine O-phosphatidyltransferase activity|CDP-diglyceride:serine phosphatidyltransferase activity|cytidine 5'-diphospho-1,2-diacyl-sn-glycerol (CDPdiglyceride):L-serine O-phosphatidyltransferase activity|CDP-diglyceride-L-serine phosphatidyltransferase activity|cytidine diphosphoglyceride-serine O-phosphatidyltransferase activity				RHEA:16913|EC:2.7.8.8|MetaCyc:PHOSPHASERSYN-RXN									molecular_function											owl:Class	
GO:0030137	biolink:NamedThing	COPI-coated vesicle	A vesicle with a coat formed of the COPI coat complex proteins. COPI-coated vesicles are found associated with Golgi membranes at steady state, are involved in Golgi to endoplasmic reticulum (retrograde) vesicle transport, and possibly also in intra-Golgi transport.	tmpzr1t_l9r_go_relaxed.owl	coatomer													cellular_component											owl:Class	
GO:0017154	biolink:NamedThing	semaphorin receptor activity	Combining with a semaphorin, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1990810	biolink:NamedThing	microtubule anchoring at mitotic spindle pole body	Any process in which a microtubule is maintained in a specific location in a cell by attachment to a mitotic spindle pole body. Microtubules attach to spindle pole bodies at the minus end.	tmpzr1t_l9r_go_relaxed.owl								vw	2015-07-24T12:52:25Z					biological_process											owl:Class	
GO:0051097	biolink:NamedThing	negative regulation of helicase activity	Any process that stops or reduces the activity of a helicase.	tmpzr1t_l9r_go_relaxed.owl	downregulation of helicase activity|down regulation of helicase activity|inhibition of helicase activity|down-regulation of helicase activity													biological_process											owl:Class	
GO:1904231	biolink:NamedThing	positive regulation of succinate dehydrogenase activity	Any process that activates or increases the frequency, rate or extent of succinate dehydrogenase activity.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of succinate:acceptor oxidoreductase activity|up-regulation of succinic acid dehydrogenase activity|upregulation of succinyl dehydrogenase activity|up regulation of succinodehydrogenase activity|activation of succinate:(acceptor) oxidoreductase activity|up-regulation of succinyl dehydrogenase activity|activation of fumarate reductase activity|up regulation of fumaric hydrogenase activity|upregulation of succinate:acceptor oxidoreductase activity|positive regulation of succinate:(acceptor) oxidoreductase activity|positive regulation of succinate oxidoreductase activity|up regulation of succinyl dehydrogenase activity|positive regulation of succinyl dehydrogenase activity|positive regulation of succinate:acceptor oxidoreductase activity|upregulation of succinic acid dehydrogenase activity|positive regulation of succinic acid dehydrogenase activity|upregulation of fumarate dehydrogenase activity|activation of fumarate dehydrogenase activity|activation of succinate dehydrogenase activity|up regulation of fumarate dehydrogenase activity|positive regulation of succinodehydrogenase activity|positive regulation of fumarate reductase activity|up-regulation of succinodehydrogenase activity|up regulation of succinate dehydrogenase activity|positive regulation of fumaric hydrogenase activity|upregulation of succinate oxidoreductase activity|up regulation of fumarate reductase activity|upregulation of succinate dehydrogenase activity|up-regulation of fumarate dehydrogenase activity|up-regulation of succinate dehydrogenase activity|positive regulation of fumarate dehydrogenase activity|upregulation of fumarate reductase activity|activation of succinic acid dehydrogenase activity|up regulation of succinate:acceptor oxidoreductase activity|activation of fumaric hydrogenase activity|upregulation of succinate:(acceptor) oxidoreductase activity|upregulation of fumaric hydrogenase activity|up-regulation of succinate oxidoreductase activity|activation of succinate:acceptor oxidoreductase activity|activation of succinyl dehydrogenase activity|up-regulation of succinate:(acceptor) oxidoreductase activity|up regulation of succinic acid dehydrogenase activity|activation of succinodehydrogenase activity|up regulation of succinate:(acceptor) oxidoreductase activity|activation of succinate oxidoreductase activity|upregulation of succinodehydrogenase activity|up-regulation of fumarate reductase activity|up-regulation of fumaric hydrogenase activity|up regulation of succinate oxidoreductase activity							rl	2015-05-15T09:51:20Z					biological_process											owl:Class	
GO:0007421	biolink:NamedThing	stomatogastric nervous system development	The process whose specific outcome is the progression of the stomatogastric nervous system over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1901894	biolink:NamedThing	regulation of ATPase-coupled calcium transmembrane transporter activity	Any process that modulates the frequency, rate or extent of an ATPase-coupled calcium transmembrane transporter activity.	tmpzr1t_l9r_go_relaxed.owl	regulation of plasma membrane Ca-ATPase|regulation of calcium transporting ATPase activity|regulation of sarco(endo)plasmic reticulum Ca2+-ATPase|regulation of calcium-transporting ATPase activity|regulation of calcium efflux ATPase|regulation of Ca2+-transporting ATPase activity|regulation of calcium-translocating P-type ATPase activity|regulation of calcium pump|regulation of sarcoplasmic reticulum ATPase|regulation of Ca(2+)-transporting ATPase activity|regulation of calcium ABC transporter|regulation of ATP phosphohydrolase (Ca2+-transporting)|regulation of Ca2+-pumping ATPase activity							rl	2013-02-06T21:18:16Z					biological_process											owl:Class	
GO:0035073	biolink:NamedThing	pupariation	The onset of prepupal development when the larval stops crawling, everts its spiracles and the larval cuticle becomes the puparium or pupal case that surrounds the organism for the duration of metamorphosis.	tmpzr1t_l9r_go_relaxed.owl	puparium biosynthesis|puparium formation													biological_process											owl:Class	
GO:0048292	biolink:NamedThing	isotype switching to IgD isotypes	The switching of activated B cells from IgM biosynthesis to IgD biosynthesis, accomplished through a recombination process involving an intrachromosomal deletion between switch regions that reside 5' of the IgM and IgD constant region gene segments in the immunoglobulin heavy chain locus.	tmpzr1t_l9r_go_relaxed.owl	class switching to IgD isotypes|isotype switch recombination to IgD isotypes					Note that this term is to be used only for gene products involved in the expression of IgD through recombinational switching into the vestigial switch region at the 5' end of the IgD gene segment, rather than gene products involved in the expression of IgD through alternative splicing mechanisms.								biological_process											owl:Class	
GO:0099404	biolink:NamedThing	mitotic sister chromatid cohesion, telomeric	The cell cycle process in which telomeres of sister chromatids are joined during mitosis.	tmpzr1t_l9r_go_relaxed.owl	sister chromatid cohesion at telomere at mitosis|mitotic sister chromatid cohesion at telomere|telomeric mitotic sister chromatin cohesion													biological_process											owl:Class	
GO:0038064	biolink:NamedThing	collagen receptor activity	Combining with a collagen and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	transmembrane collagen receptor activity							bf	2012-01-18T01:52:42Z					molecular_function											owl:Class	
GO:0038065	biolink:NamedThing	collagen-activated signaling pathway	A series of molecular signals initiated by collagen binding to a cell surface receptor, and ending with regulation of a downstream cellular process, e.g. transcription.	tmpzr1t_l9r_go_relaxed.owl	collagen-activated signalling pathway							bf	2012-01-18T01:57:37Z					biological_process											owl:Class	
GO:0032839	biolink:NamedThing	dendrite cytoplasm	All of the contents of a dendrite, excluding the surrounding plasma membrane.	tmpzr1t_l9r_go_relaxed.owl	dendritic cytoplasm													cellular_component											owl:Class	
GO:0019958	biolink:NamedThing	C-X-C chemokine binding	Binding to a C-X-C chemokine; C-X-C chemokines have a single amino acid between the first two cysteines of the characteristic four cysteine motif.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0120078	biolink:NamedThing	cell adhesion involved in sprouting angiogenesis	The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules that contributes to the formation of a blood vessel network.	tmpzr1t_l9r_go_relaxed.owl	cell adhesion involved in blood vessel anastomosis|cell adhesion involved in vascular anastomosis	https://github.com/geneontology/go-ontology/issues/13690						krc	2017-06-27T21:29:47Z					biological_process											owl:Class	
GO:0070562	biolink:NamedThing	regulation of vitamin D receptor signaling pathway	Any process that modulates the frequency, rate or extent of vitamin D receptor signaling pathway activity.	tmpzr1t_l9r_go_relaxed.owl	regulation of vitamin D receptor signalling pathway|regulation of VDR signaling pathway							mah	2009-04-14T01:46:03Z					biological_process											owl:Class	
GO:0070561	biolink:NamedThing	vitamin D receptor signaling pathway	The series of molecular signals generated as a consequence of a vitamin D receptor binding to one of its physiological ligands.	tmpzr1t_l9r_go_relaxed.owl	vitamin D receptor signalling pathway|VDR signaling pathway|calcitriol signaling pathway							mah	2009-04-14T01:43:59Z					biological_process											owl:Class	
GO:0010658	biolink:NamedThing	striated muscle cell apoptotic process	A form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases, whose actions dismantle a striated muscle cell and result in its death. Striated muscle cells make up striated muscle fibers which are divided by transverse bands into striations.	tmpzr1t_l9r_go_relaxed.owl	striated muscle cell apoptosis													biological_process											owl:Class	
GO:0015737	biolink:NamedThing	galacturonate transmembrane transport	The process in which galacturonate is transported across a lipid bilayer, from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	galacturonate transport													biological_process											owl:Class	
GO:0034485	biolink:NamedThing	phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity	Catalysis of the reaction: phosphatidylinositol-3,4,5-trisphosphate + H2O = phosphatidylinositol-3,4-bisphosphate + phosphate.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-1675949|RHEA:25528|MetaCyc:RXN-10036									molecular_function											owl:Class	
GO:1903039	biolink:NamedThing	positive regulation of leukocyte cell-cell adhesion	Any process that activates or increases the frequency, rate or extent of leukocyte cell-cell adhesion.	tmpzr1t_l9r_go_relaxed.owl	upregulation of leukocyte cell adhesion|up-regulation of leukocyte adhesion|upregulation of leukocyte adhesion|activation of leukocyte adhesion|up regulation of leukocyte adhesion|positive regulation of leukocyte cell adhesion|up-regulation of leukocyte cell-cell adhesion|up regulation of leukocyte cell-cell adhesion|up regulation of leukocyte cell adhesion|positive regulation of leukocyte adhesion|activation of leukocyte cell-cell adhesion|upregulation of leukocyte cell-cell adhesion|up-regulation of leukocyte cell adhesion|activation of leukocyte cell adhesion					Exogenous expression of ASS1 or NOS3 in HUVECs enhances NO production and inhibits monocyte adhesion		rl	2014-05-19T15:30:15Z					biological_process											owl:Class	
GO:0002098	biolink:NamedThing	tRNA wobble uridine modification	The process in which a uridine in position 34 of a tRNA is post-transcriptionally modified.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1904437	biolink:NamedThing	positive regulation of transferrin receptor binding	Any process that activates or increases the frequency, rate or extent of transferrin receptor binding.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of transferrin receptor binding|upregulation of transferrin receptor binding|activation of transferrin receptor binding|up regulation of transferrin receptor binding							kom	2015-07-06T13:49:13Z					biological_process											owl:Class	
GO:1990459	biolink:NamedThing	transferrin receptor binding	Binding to a transferrin receptor.	tmpzr1t_l9r_go_relaxed.owl								tb	2014-08-18T20:14:24Z					molecular_function											owl:Class	
GO:0002322	biolink:NamedThing	B cell proliferation involved in immune response	The expansion of a B cell population by cell division following B cell activation during an immune response.	tmpzr1t_l9r_go_relaxed.owl	B cell proliferation during immune response|B-lymphocyte proliferation during immune response|B-cell proliferation during immune response|B lymphocyte proliferation during immune response													biological_process											owl:Class	
GO:0005947	biolink:NamedThing	mitochondrial alpha-ketoglutarate dehydrogenase complex	Mitochondrial complex that possesses alpha-ketoglutarate dehydrogenase activity.	tmpzr1t_l9r_go_relaxed.owl	2-oxoglutarate dehydrogenase complex													cellular_component											owl:Class	
GO:0004102	biolink:NamedThing	choline O-acetyltransferase activity	Catalysis of the reaction: acetyl-CoA + choline = acetylcholine + CoA.	tmpzr1t_l9r_go_relaxed.owl	CHOACTase activity|acetyl-CoA:choline O-acetyltransferase activity|choline acetylase activity|choline acetyltransferase activity				EC:2.3.1.6|KEGG_REACTION:R01023|RHEA:18821|MetaCyc:CHOLINE-O-ACETYLTRANSFERASE-RXN|Reactome:R-HSA-264622									molecular_function											owl:Class	
GO:0006351	biolink:NamedThing	transcription, DNA-templated	The cellular synthesis of RNA on a template of DNA.	tmpzr1t_l9r_go_relaxed.owl	transcription|DNA-dependent transcription|transcription from bacterial-type RNA polymerase promoter|bacterial transcription|cellular transcription|transcription, DNA-dependent	https://github.com/geneontology/go-ontology/issues/16737|https://github.com/geneontology/go-ontology/issues/22258|https://github.com/geneontology/go-ontology/issues/14854			Wikipedia:Transcription_(genetics)							GO:0001121|GO:0061018|GO:0061022|GO:0006350		biological_process											owl:Class	
GO:0035026	biolink:NamedThing	leading edge cell differentiation	The process in which relatively unspecialized cells acquire specialized structural and/or functional features of leading edge cells, cells at the front of a migrating epithelial sheet.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0090237	biolink:NamedThing	regulation of arachidonic acid secretion	Any process that modulates the rate, frequency, or extent of arachidonic acid secretion, the controlled release of arachidonic acid from a cell or a tissue.	tmpzr1t_l9r_go_relaxed.owl								tb	2010-01-20T03:32:22Z					biological_process											owl:Class	
GO:0060291	biolink:NamedThing	long-term synaptic potentiation	A process that modulates synaptic plasticity such that synapses are changed resulting in the increase in the rate, or frequency of synaptic transmission at the synapse.	tmpzr1t_l9r_go_relaxed.owl	LTP|long-term potentiation													biological_process											owl:Class	
GO:0045618	biolink:NamedThing	positive regulation of keratinocyte differentiation	Any process that activates or increases the frequency, rate or extent of keratinocyte differentiation.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of keratinocyte differentiation|up regulation of keratinocyte differentiation|stimulation of keratinocyte differentiation|upregulation of keratinocyte differentiation|activation of keratinocyte differentiation													biological_process											owl:Class	
GO:0001569	biolink:NamedThing	branching involved in blood vessel morphogenesis	The process of coordinated growth and sprouting of blood vessels giving rise to the organized vascular system.	tmpzr1t_l9r_go_relaxed.owl	patterning of blood vessels													biological_process											owl:Class	
GO:0071631	biolink:NamedThing	mating pheromone secretion involved in positive regulation of conjugation with cellular fusion	The regulated release of a mating pheromone, a peptide hormone that induces a behavioral or physiological response(s) from a responding organism or cell, that positively regulates a conjugation process that results in the union of cellular and genetic information from compatible mating types.	tmpzr1t_l9r_go_relaxed.owl	mating-type pheromone secretion involved in conjugation with cellular fusion							mah	2010-02-11T03:36:57Z					biological_process											owl:Class	
GO:0015826	biolink:NamedThing	threonine transport	The directed movement of threonine, (2R*,3S*)-2-amino-3-hydroxybutanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	L-threonine transport													biological_process											owl:Class	
GO:0010319	biolink:NamedThing	stromule	Thin filamentous structure extending from the surface of all plastid types examined so far, including chloroplast, proplastid, etioplast, leucoplast, amyloplast, and chromoplast. In general, stromules are more abundant in tissues containing non-green plastids, and in cells containing smaller plastids. The primary function of stromules is still unresolved, although the presence of stromules markedly increases the plastid surface area, potentially increasing transport to and from the cytosol. Other functions of stromules, such as transfer of macromolecules between plastids and starch granule formation in cereal endosperm, may be restricted to particular tissues and cell types.	tmpzr1t_l9r_go_relaxed.owl	Stroma-filled tubule				Wikipedia:Stromule									cellular_component											owl:Class	
GO:0035283	biolink:NamedThing	central nervous system segmentation	Division of the central nervous system into a series of semi-repetitive parts or segments.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0042093	biolink:NamedThing	T-helper cell differentiation	The process in which a relatively unspecialized thymocyte acquires specialized features of a T-helper cell.	tmpzr1t_l9r_go_relaxed.owl	T-helper cell development|helper T cell differentiation													biological_process											owl:Class	
GO:0051598	biolink:NamedThing	meiotic recombination checkpoint signaling	A signaling process that contributes to a meiotic recombination checkpoint, that acts during late prophase I (pachytene) and prevents segregation of homologous chromosomes until recombination is completed, ensuring proper distribution of the genetic material to the gametes.	tmpzr1t_l9r_go_relaxed.owl	pachytene checkpoint|signal transduction involved in meiotic recombination checkpoint|meiotic recombination checkpoint	https://github.com/geneontology/go-ontology/issues/20935										GO:0072462		biological_process											owl:Class	
GO:2000902	biolink:NamedThing	cellooligosaccharide metabolic process	The chemical reactions and pathways involving a cellooligosaccharide.	tmpzr1t_l9r_go_relaxed.owl	cellooligosaccharide metabolism							jl	2011-07-28T03:21:46Z					biological_process											owl:Class	
GO:0010977	biolink:NamedThing	negative regulation of neuron projection development	Any process that decreases the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites).	tmpzr1t_l9r_go_relaxed.owl	growth cone collapse|negative regulation of neurite development|negative regulation of neurite biosynthesis|negative regulation of neurite formation|negative regulation of neurite growth							tb	2009-06-01T10:47:42Z					biological_process											owl:Class	
GO:0097003	biolink:NamedThing	adipokinetic hormone receptor activity	Combining with an adipokinetic hormone to initiate a change in cell activity. Adipokinetic hormones (AKHs) are protein or peptide hormones that are important for sugar and fat homeostasis in metazoa. In insects, they mobilize sugar and lipids from the insect fat body during energy-requiring activities such as flight and locomotion. They also contribute to hemolymph sugar homeostasis.	tmpzr1t_l9r_go_relaxed.owl	AKH receptor activity							pr	2011-03-14T10:24:08Z					molecular_function											owl:Class	
GO:0055100	biolink:NamedThing	adiponectin binding	Binding to adiponectin, a protein hormone produced by adipose tissue that modulates a number of metabolic processes, including glucose regulation and fatty acid catabolism.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0045333	biolink:NamedThing	cellular respiration	The enzymatic release of energy from inorganic and organic compounds (especially carbohydrates and fats) which either requires oxygen (aerobic respiration) or does not (anaerobic respiration).	tmpzr1t_l9r_go_relaxed.owl	oxidative metabolic process|respiration|oxidative metabolism				Wikipedia:Cellular_respiration									biological_process											owl:Class	
GO:0090238	biolink:NamedThing	positive regulation of arachidonic acid secretion	Any process that increases the rate, frequency, or extent of arachidonic acid secretion, the controlled release of arachidonic acid from a cell or a tissue.	tmpzr1t_l9r_go_relaxed.owl								tb	2010-01-20T03:32:22Z					biological_process											owl:Class	
GO:0097149	biolink:NamedThing	centralspindlin complex	A heterotetrameric protein complex playing a key role in the formation of the central spindle in mitosis. Made up of two molecules each of a mitotic kinesin (ZEN-4 in Caenorhabditis elegans or MKLP1 in mammals) and of two molecules each of a GTPase activating protein (GAP) factor (CYK-4 in Caenorhabditis elegans or MgcRacGAP in mammals).	tmpzr1t_l9r_go_relaxed.owl								pr	2011-08-04T11:15:37Z					cellular_component											owl:Class	
GO:0060729	biolink:NamedThing	intestinal epithelial structure maintenance	A tissue homeostatic process required for the maintenance of the structure of the intestinal epithelium.	tmpzr1t_l9r_go_relaxed.owl	epithelial structure maintenance of intestine|maintenance of intestinal epithelium							dph	2009-06-12T01:44:52Z					biological_process											owl:Class	
GO:0072241	biolink:NamedThing	metanephric DCT cell development	The process whose specific outcome is the progression of a metanephric distal convoluted tubule cell over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl	metanephric distal convoluted tubule cell development							mah	2010-03-19T03:26:44Z					biological_process											owl:Class	
GO:0002344	biolink:NamedThing	B cell affinity maturation	The process in which B cells produce antibodies with increased antigen affinity. This is accomplished by somatic hypermutation and selection for B cells which produce higher affinity antibodies to antigen.	tmpzr1t_l9r_go_relaxed.owl	B-lymphocyte affinity maturation|B lymphocyte affinity maturation|B-cell affinity maturation													biological_process											owl:Class	
GO:0061171	biolink:NamedThing	establishment of bipolar cell polarity	The specification and formation of bipolar intracellular organization or cell growth patterns. Bipolar organization is the organization that is a mirror image along an axis from a plane.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-06-30T08:49:38Z					biological_process											owl:Class	
GO:0032633	biolink:NamedThing	interleukin-4 production	The appearance of interleukin-4 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	tmpzr1t_l9r_go_relaxed.owl	interleukin-4 biosynthetic process|interleukin-4 secretion|IL-4 production											GO:0042224|GO:0072602|GO:0042097		biological_process											owl:Class	
GO:0003052	biolink:NamedThing	circadian regulation of systemic arterial blood pressure	Any process in which an organism modulates its blood pressure at different values with a regularity of approximately 24 hours.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0048350	biolink:NamedThing	positive regulation of paraxial mesodermal cell fate specification	Any process that activates or increases the frequency, rate or extent of paraxial mesoderm cell fate specification.	tmpzr1t_l9r_go_relaxed.owl	upregulation of paraxial mesodermal cell fate specification|stimulation of paraxial mesodermal cell fate specification|up regulation of paraxial mesodermal cell fate specification|up-regulation of paraxial mesodermal cell fate specification|activation of paraxial mesodermal cell fate specification													biological_process											owl:Class	
GO:0048348	biolink:NamedThing	paraxial mesodermal cell fate specification	The process in which a cell becomes capable of differentiating autonomously into a paraxial mesoderm cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0030297	biolink:NamedThing	transmembrane receptor protein tyrosine kinase activator activity	Binds to and increases the activity of a transmembrane receptor protein tyrosine kinase.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0007171	biolink:NamedThing	activation of transmembrane receptor protein tyrosine kinase activity	Any process that initiates the activity of the inactive transmembrane receptor protein tyrosine kinase activity.	tmpzr1t_l9r_go_relaxed.owl	transmembrane receptor protein tyrosine kinase activation|transmembrane receptor protein tyrosine kinase dimerization													biological_process											owl:Class	
GO:1904662	biolink:NamedThing	positive regulation of sensory perception of bitter taste	Any process that activates or increases the frequency, rate or extent of sensory perception of bitter taste.	tmpzr1t_l9r_go_relaxed.owl	activation of bitter taste perception|up-regulation of bitter taste perception|positive regulation of bitter taste perception|activation of sensory perception of bitter taste|up regulation of sensory perception of bitter taste|up regulation of bitter taste perception|upregulation of bitter taste perception|upregulation of sensory perception of bitter taste|up-regulation of sensory perception of bitter taste							mr	2015-09-04T17:54:22Z					biological_process											owl:Class	
GO:0050913	biolink:NamedThing	sensory perception of bitter taste	The series of events required to receive a bitter taste stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.	tmpzr1t_l9r_go_relaxed.owl	bitter taste perception													biological_process											owl:Class	
GO:0042799	biolink:NamedThing	histone methyltransferase activity (H4-K20 specific)	Catalysis of the reaction: S-adenosyl-L-methionine + histone H4 L-lysine (position 20) = S-adenosyl-L-homocysteine + histone H4 N6-methyl-L-lysine (position 20). This reaction is the addition of a methyl group onto lysine at position 20 of the histone H4 protein.	tmpzr1t_l9r_go_relaxed.owl	histone H4 lysine 20-specific methyltransferase activity|histone methylase activity (H4-K20 specific)|histone lysine N-methyltransferase activity (H4-K20 specific)				Reactome:R-HSA-5682965|Reactome:R-HSA-2301205	Note that in some species, the methyl group may be added to a lysine in a slightly different position of the histone H4 protein, but that this term still applies.								molecular_function											owl:Class	
GO:0007418	biolink:NamedThing	ventral midline development	The process whose specific outcome is the progression of the ventral midline over time, from its formation to the mature structure. In protostomes (such as insects, snails and worms) as well as deuterostomes (vertebrates), the midline is an embryonic region that functions in patterning of the adjacent nervous tissue. The ventral midline in insects is a cell population extending along the ventral surface of the embryo and is the region from which cells detach to form the ventrally located nerve cords. In vertebrates, the midline is originally located dorsally. During development, it folds inwards and becomes the ventral part of the dorsally located neural tube and is then called the ventral midline, or floor plate.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0099051	biolink:NamedThing	vesicle scission involved in endocytosis	The membrane scission process that is the final step in the formation of an endocytic vesicle: separation from the plasma membrane.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0060838	biolink:NamedThing	lymphatic endothelial cell fate commitment	The commitment of a venous blood vessel endothelial cell to a lymphatic endothelial cell fate and its capacity to differentiate into a lymphatic endothelial cell.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-08-11T03:51:45Z					biological_process											owl:Class	
GO:0060836	biolink:NamedThing	lymphatic endothelial cell differentiation	The process in which a venous blood vessel endothelial cell acquires specialized features of a lymphatic vessel endothelial cell, a thin flattened cell that lines the inside surfaces of lymph vessels.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-08-11T03:45:20Z					biological_process											owl:Class	
GO:0004849	biolink:NamedThing	uridine kinase activity	Catalysis of the reaction: ATP + uridine = ADP + UMP.	tmpzr1t_l9r_go_relaxed.owl	uridine-cytidine kinase activity|uridine kinase (phosphorylating)|pyrimidine ribonucleoside kinase activity|uridine kinase reaction|ATP:uridine 5'-phosphotransferase activity|uridine monophosphokinase activity|uridine phosphokinase activity				RHEA:16825|Reactome:R-HSA-8954327|EC:2.7.1.48|MetaCyc:URIDINEKIN-RXN									molecular_function											owl:Class	
GO:0006297	biolink:NamedThing	nucleotide-excision repair, DNA gap filling	Repair of the gap in the DNA helix by DNA polymerase and DNA ligase after the portion of the strand containing the lesion has been removed by pyrimidine-dimer repair enzymes.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0061739	biolink:NamedThing	protein lipidation involved in autophagosome assembly	The protein lipidation process by which phosphatidylethanolamine is conjugated to a protein of the ATG8 family, leading to membrane insertion of the protein as a step in autophagosome assembly.	tmpzr1t_l9r_go_relaxed.owl								dph	2015-10-14T12:02:01Z					biological_process											owl:Class	
GO:0030219	biolink:NamedThing	megakaryocyte differentiation	The process in which a myeloid precursor cell acquires specializes features of a megakaryocyte.	tmpzr1t_l9r_go_relaxed.owl	megakaryocyte cell differentiation													biological_process											owl:Class	
GO:0016321	biolink:NamedThing	female meiosis chromosome segregation	The cell cycle process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets during the meiotic cell cycle in a female.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0008354	biolink:NamedThing	germ cell migration	The orderly movement of a cell specialized to produce haploid gametes through the embryo from its site of production to the place where the gonads will form.	tmpzr1t_l9r_go_relaxed.owl	primordial germ cell migration|germ-cell migration													biological_process											owl:Class	
GO:0061231	biolink:NamedThing	mesonephric glomerulus vasculature development	The biological process whose specific outcome is the progression of a mesonephric glomerulus vasculature from an initial condition to its mature state. This process begins with the formation of the mesonephric glomerulus vasculature and ends with the mature structure. The mesonephric glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the mesonephric glomerulus.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-08-19T02:47:06Z					biological_process											owl:Class	
GO:0009846	biolink:NamedThing	pollen germination	The physiological and developmental changes that occur in a heterosporous plant pollen grain, beginning with hydration and terminating with the emergence of the pollen tube through the aperture.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0022616	biolink:NamedThing	DNA strand elongation	The DNA metabolic process in which an existing DNA strand is extended by activities including the addition of nucleotides to the 3' end of the strand.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/12633												biological_process											owl:Class	
GO:0061643	biolink:NamedThing	chemorepulsion of axon	The process in which a neuron growth cone is directed to a specific target site in response to a repulsive chemical cue.	tmpzr1t_l9r_go_relaxed.owl								dph	2014-08-29T08:35:40Z					biological_process											owl:Class	
GO:0002419	biolink:NamedThing	T cell mediated cytotoxicity directed against tumor cell target	The directed killing of a tumor cell by a T cell through the release of granules containing cytotoxic mediators or through the engagement of death receptors.	tmpzr1t_l9r_go_relaxed.owl	T-lymphocyte mediated cytotoxicity directed against tumor cell target|T-cell mediated cytotoxicity directed against tumor cell target|T lymphocyte mediated cytotoxicity directed against tumor cell target					Note that either or both mechanisms mentioned in the definition may be used in this process. Note that both granule release and the engagement of death receptors on target cells result in induction of apoptosis in the target cell.								biological_process											owl:Class	
GO:0061262	biolink:NamedThing	mesonephric renal vesicle formation	The developmental process pertaining to the initial formation of the mesonephros.	tmpzr1t_l9r_go_relaxed.owl	mesonephros formation							dph	2010-08-30T02:41:20Z					biological_process											owl:Class	
GO:1901614	biolink:NamedThing	positive regulation of terminal button organization	Any process that activates or increases the frequency, rate or extent of terminal button organization.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of synaptic bouton organization|up regulation of terminal button organization|up-regulation of terminal bouton organization|positive regulation of presynaptic bouton organization|upregulation of terminal button organization|up-regulation of terminal button organisation|up-regulation of terminal button organization|activation of presynaptic bouton organization|positive regulation of terminal bouton organization|activation of bouton organization|upregulation of bouton organization|positive regulation of bouton organization|up regulation of bouton organization|up regulation of terminal button organisation|up regulation of terminal bouton organization|up regulation of presynaptic bouton organization|activation of terminal button organization|upregulation of synaptic bouton organization|activation of terminal button organisation|up regulation of synaptic bouton organization|positive regulation of terminal button organisation|positive regulation of synaptic bouton organization|upregulation of terminal button organisation|activation of synaptic bouton organization|up-regulation of presynaptic bouton organization|activation of terminal bouton organization|upregulation of presynaptic bouton organization|up-regulation of bouton organization|upregulation of terminal bouton organization							lb	2012-11-13T10:40:58Z					biological_process											owl:Class	
GO:0033278	biolink:NamedThing	cell proliferation in midbrain	The multiplication or reproduction of cells, resulting in the expansion of a cell population in the midbrain.	tmpzr1t_l9r_go_relaxed.owl	mesencepahalic cell proliferation|cell proliferation in mesencephalon													biological_process											owl:Class	
GO:0042730	biolink:NamedThing	fibrinolysis	A process that solubilizes fibrin in the bloodstream of a multicellular organism, chiefly by the proteolytic action of plasmin.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Fibrinolysis									biological_process											owl:Class	
GO:1905457	biolink:NamedThing	negative regulation of lymphoid progenitor cell differentiation	Any process that stops, prevents or reduces the frequency, rate or extent of lymphoid progenitor cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	downregulation of lymphoid progenitor cell differentiation|inhibition of lymphoid progenitor cell differentiation|down-regulation of lymphoid progenitor cell differentiation|down regulation of lymphoid progenitor cell differentiation							rz	2016-09-16T12:32:48Z					biological_process											owl:Class	
GO:0060767	biolink:NamedThing	epithelial cell proliferation involved in prostate gland development	The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population that contributes to the progression of the prostate gland over time.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-07-08T07:32:34Z					biological_process											owl:Class	
GO:0019003	biolink:NamedThing	GDP binding	Binding to GDP, guanosine 5'-diphosphate.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0036364	biolink:NamedThing	transforming growth factor beta1 activation	The release of transforming growth factor beta1 (TGF-beta1) from its latent state.	tmpzr1t_l9r_go_relaxed.owl	TGFB1 activation|TGF-beta 1 activation|transforming growth factor-beta1 activation|L-TGF-beta 1 activation|latent-TGF-beta1 activation|TGFbeta 1 activation							bf	2012-09-24T10:09:02Z					biological_process											owl:Class	
GO:0034982	biolink:NamedThing	mitochondrial protein processing	The peptide cleavage of mitochondrial proteins, including cleavage contributing to their import.	tmpzr1t_l9r_go_relaxed.owl	mitochondrial protein modification													biological_process											owl:Class	
GO:1900458	biolink:NamedThing	negative regulation of brassinosteroid mediated signaling pathway	Any process that stops, prevents or reduces the frequency, rate or extent of brassinosteroid mediated signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	downregulation of brassinosteroid mediated signaling pathway|inhibition of brassinosteroid mediated signaling pathway|negative regulation of brassinosteroid mediated signalling|down-regulation of brassinosteroid mediated signaling pathway|inhibition of brassinosteroid mediated signalling|down regulation of brassinosteroid mediated signalling|downregulation of brassinosteroid mediated signalling|down regulation of brassinosteroid mediated signaling pathway|down-regulation of brassinosteroid mediated signalling							dhl	2012-05-01T06:12:13Z					biological_process											owl:Class	
GO:0009742	biolink:NamedThing	brassinosteroid mediated signaling pathway	A series of molecular signals mediated by the detection of brassinosteroid.	tmpzr1t_l9r_go_relaxed.owl	brassinosteroid mediated signalling													biological_process											owl:Class	
GO:0050845	biolink:NamedThing	teichuronic acid biosynthetic process	The chemical reactions and pathways resulting in the formation of teichuronic acid, a polymer containing chains of uronic acids and N-acetylglucosamine found in the cell wall, membrane or capsule of Gram-positive bacteria.	tmpzr1t_l9r_go_relaxed.owl	teichuronic acid biosynthesis|teichuronic acid synthesis|teichuronic acid formation|teichuronic acid anabolism													biological_process											owl:Class	
GO:1904496	biolink:NamedThing	positive regulation of substance P secretion, neurotransmission	Any process that activates or increases the frequency, rate or extent of substance P secretion, neurotransmission.	tmpzr1t_l9r_go_relaxed.owl	upregulation of substance P secretion, neurotransmission|activation of substance P secretion, neurotransmission|up regulation of substance P secretion, neurotransmission|up-regulation of substance P secretion, neurotransmission							sl	2015-07-21T19:09:16Z					biological_process											owl:Class	
GO:0055011	biolink:NamedThing	atrial cardiac muscle cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a cardiac muscle cell in the atrium. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction. The atrium is the part of the heart that receives blood into the organ.	tmpzr1t_l9r_go_relaxed.owl	atrial cardiomyocyte differentiation|atrial heart muscle cell differentiation													biological_process											owl:Class	
GO:0036504	biolink:NamedThing	Golgi membrane fusion	The joining of two lipid bilayers that surround the Golgi apparatus to form a single Golgi membrane.	tmpzr1t_l9r_go_relaxed.owl	post-mitotic fusion of Golgi membranes|membrane fusion involved in Golgi reassembly							bf	2015-05-21T10:05:06Z					biological_process											owl:Class	
GO:0090168	biolink:NamedThing	Golgi reassembly	The reformation of the Golgi following its breakdown and partitioning contributing to Golgi inheritance.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-12-08T09:15:11Z					biological_process											owl:Class	
GO:0034253	biolink:NamedThing	positive regulation of cellular amide catabolic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of amides.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of amide breakdown|positive regulation of amide degradation|positive regulation of amide catabolism													biological_process											owl:Class	
GO:0015440	biolink:NamedThing	ABC-type peptide transporter activity	Catalysis of the reaction: ATP + H2O + peptide(in) = ADP + phosphate + peptide(out). Peptides exported include alpha-hemolysin, cyclolysin, colicin V and siderophores from Gram-negative bacteria, and bacteriocin, subtilin, competence factor and pediocin from Gram-positive bacteria.	tmpzr1t_l9r_go_relaxed.owl	ATPase-coupled peptide transmembrane transporter activity|peptide-transporting ATPase activity|peptide ABC transporter|ATP-dependent peptide transmembrane transporter activity				MetaCyc:3.6.3.43-RXN|EC:7.4.2.5|RHEA:14429									molecular_function											owl:Class	
GO:0061265	biolink:NamedThing	mesonephric nephron tubule epithelial cell differentiation	The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the mesonephric nephron tubule as it progresses from its formation to the mature state.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-08-30T03:02:09Z					biological_process											owl:Class	
GO:0021992	biolink:NamedThing	cell proliferation involved in neural plate elongation	The process of expansion of cell numbers in the neural plate due to cell division of progenitor cells preferentially in the rostrocaudal direction, resulting in the elongation of the tissue.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0000152	biolink:NamedThing	nuclear ubiquitin ligase complex	A ubiquitin ligase complex found in the nucleus.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0044385	biolink:NamedThing	integral to membrane of host cell	Penetrating at least one phospholipid bilayer of a membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer. When used to describe a protein, indicates that all or part of the peptide sequence is embedded in the membrane. Occurring in a host cell.	tmpzr1t_l9r_go_relaxed.owl								jl	2011-12-13T04:08:03Z					cellular_component											owl:Class	
GO:1900408	biolink:NamedThing	negative regulation of cellular response to oxidative stress	Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to oxidative stress.	tmpzr1t_l9r_go_relaxed.owl	downregulation of adaptive response to oxidative stress|inhibition of adaptive response to oxidative stress|negative regulation of adaptive response to oxidative stress|down regulation of cellular response to oxidative stress|downregulation of cellular response to oxidative stress|inhibition of cellular response to oxidative stress|down-regulation of adaptive response to oxidative stress|down regulation of adaptive response to oxidative stress|down-regulation of cellular response to oxidative stress							mah	2012-04-20T03:31:05Z					biological_process											owl:Class	
GO:0006930	biolink:NamedThing	substrate-dependent cell migration, cell extension	The formation of a cell surface protrusion, such as a lamellipodium or filopodium, at the leading edge of a migrating cell.	tmpzr1t_l9r_go_relaxed.owl	substrate-bound cell migration, cell extension													biological_process											owl:Class	
GO:0097188	biolink:NamedThing	dentin mineralization	The process in which calcium salts are deposited into the calcareous tooth structure known as dentin.	tmpzr1t_l9r_go_relaxed.owl	dentine mineralization							pr	2011-11-21T09:05:43Z					biological_process											owl:Class	
GO:1905319	biolink:NamedThing	mesenchymal stem cell migration	The orderly movement of a mesenchymal stem cell from one site to another.	tmpzr1t_l9r_go_relaxed.owl								sl	2016-07-14T17:13:02Z					biological_process											owl:Class	
GO:0060603	biolink:NamedThing	mammary gland duct morphogenesis	The process in which anatomical structures of the mammary ducts are generated and organized. Mammary ducts are epithelial tubes that transport milk.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-05-15T09:22:25Z					biological_process											owl:Class	
GO:0048826	biolink:NamedThing	cotyledon morphogenesis	The process in which the anatomical structures of the cotyledon are generated and organized. The cotyledon is the modified leaf (seed leaf), found as part of the embryo in plant seeds. It is involved in either storage or absorption of food reserves. Dicotyledonous seeds contain two cotyledons, while monocotyledonous seeds contain only one. The cotyledons may appear above ground and show photosynthetic activity in the seedling.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0005895	biolink:NamedThing	interleukin-5 receptor complex	A protein complex that binds interleukin-3; comprises an alpha and a beta subunit. The alpha chain is specific to the interleukin-5 receptor, whereas the beta chain is shared with the receptors for granulocyte-macrophage colony-stimulating factor and interleukin-3.	tmpzr1t_l9r_go_relaxed.owl	IL-5 receptor complex													cellular_component											owl:Class	
GO:0019911	biolink:NamedThing	structural constituent of myelin sheath	The action of a molecule that contributes to the structural integrity of the myelin sheath of a nerve.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0043209	biolink:NamedThing	myelin sheath	An electrically insulating fatty layer that surrounds the axons of many neurons. It is an outgrowth of glial cells: Schwann cells supply the myelin for peripheral neurons while oligodendrocytes supply it to those of the central nervous system.	tmpzr1t_l9r_go_relaxed.owl	astrocyte sheath|oligodendrocyte myelin sheath|Schwann cell myelin sheath				FMA:62983|NIF_Subcellular:sao593830697|Wikipedia:Myelin									cellular_component											owl:Class	
GO:0051260	biolink:NamedThing	protein homooligomerization	The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of identical component monomers. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer.	tmpzr1t_l9r_go_relaxed.owl	protein homooligomer formation|protein homooligomerization activity|protein homooligomer biosynthetic process|protein homooligomer biosynthesis|protein homooligomer assembly													biological_process											owl:Class	
GO:0051031	biolink:NamedThing	tRNA transport	The directed movement of tRNA, transfer ribonucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0007395	biolink:NamedThing	dorsal closure, spreading of leading edge cells	Dorsally-directed movement of a cell at the leading edge of the epithelium over the amnioserosa.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0038031	biolink:NamedThing	non-canonical Wnt signaling pathway via JNK cascade	The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, where the signal is passed on via the JNK cascade.	tmpzr1t_l9r_go_relaxed.owl	non-canonical Wnt receptor signalling pathway via JNK cascade|non-canonical Wnt-activated signaling pathway via JNK cascade|non-canonical Wnt receptor signaling pathway via JNK cascade							bf	2011-09-08T01:57:10Z					biological_process											owl:Class	
GO:0031105	biolink:NamedThing	septin complex	A protein complex containing septins.  Typically, these complexes contain multiple septins and are oligomeric.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:2000534	biolink:NamedThing	positive regulation of renal albumin absorption	Any process that activates or increases the frequency, rate or extent of renal albumin absorption.	tmpzr1t_l9r_go_relaxed.owl								pr	2011-03-24T03:28:14Z					biological_process											owl:Class	
GO:0061371	biolink:NamedThing	determination of heart left/right asymmetry	Determination of the asymmetric location of the heart with respect to the left and right halves of the organism.	tmpzr1t_l9r_go_relaxed.owl	determination of cardiac left/right asymmetry							dph	2010-11-03T02:13:58Z					biological_process											owl:Class	
GO:0021712	biolink:NamedThing	candelabrum cell differentiation	The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature candelabrum cell. Differentiation includes the processes involved in commitment of a neuroblast to a candelabrum cell fate. A candelabrum cell is an inhibitory GABAergic interneuron found in the cerebellar cortex.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0070209	biolink:NamedThing	ASTRA complex	A protein complex that is part of the chromatin remodeling machinery; the acronym stands for ASsembly of Tel, Rvb and Atm-like kinase. In Saccharomyces cerevisiae this complex includes Rvb1p, Rvb2p, Tra1p, Tel2p, Asa1p, Ttilp and Tti2p.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0061370	biolink:NamedThing	testosterone biosynthetic process	The chemical reactions and pathways resulting in the formation of testosterone, an androgen having 17beta-hydroxy and 3-oxo groups, together with unsaturation at C-4 C-5.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-10-27T02:50:48Z					biological_process											owl:Class	
GO:0089722	biolink:NamedThing	phosphoenolpyruvate transmembrane transport	The directed movement of phosphoenolpytuvate across a membrane.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0061137	biolink:NamedThing	bud dilation	The process in which a branch bud increases radially. A branch bud is the initial area of outgrowth in the formation of a new branch.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-05-20T07:54:42Z					biological_process											owl:Class	
GO:0019834	biolink:NamedThing	phospholipase A2 inhibitor activity	Binds to and stops, prevents or reduces the activity of phospholipase A2.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0140380	biolink:NamedThing	psilocybin biosynthetic process	The chemical reactions and pathways resulting in the formation of psilocybin, a psychotropic tryptamine-derived natural product.	tmpzr1t_l9r_go_relaxed.owl								pg	2019-11-20T10:03:05Z					biological_process											owl:Class	
GO:0140383	biolink:NamedThing	4-hydroxytryptamine kinase activity	Catalysis of the reaction: 4-hydroxytryptamine + ATP = 4-hydoxytryptamine 4-phosphate + ADP + H(+).	tmpzr1t_l9r_go_relaxed.owl					RHEA:55564|EC:2.7.1.222			pg	2019-11-20T10:30:05Z					molecular_function											owl:Class	
GO:0004709	biolink:NamedThing	MAP kinase kinase kinase activity	Catalysis of the phosphorylation and activation of a MAP kinase kinase; each MAP kinase kinase can be phosphorylated by any of several MAP kinase kinase kinases.	tmpzr1t_l9r_go_relaxed.owl	MAP3K|MLTK|MEKK|MEK kinase activity|MEKK2|ATP:protein phosphotransferase (MAPKKKK-activated) activity|MLK-like mitogen-activated protein triple kinase activity|Mil/Raf|cRaf|REKS|MEKK1|STK28|MEKK activity|MLTKb|mitogen-activated protein kinase kinase kinase activity|MAPK/ERK kinase kinase activity|MEKK3|cMos|MLTKa|MAPKKK activity				Reactome:R-HSA-727819|Reactome:R-HSA-451649|Reactome:R-HSA-392530|MetaCyc:2.7.11.25-RXN|EC:2.7.11.25|Reactome:R-HSA-168184|Reactome:R-HSA-933530|Reactome:R-HSA-450337|Reactome:R-HSA-450346|Reactome:R-HSA-2730887							GO:0004710		molecular_function											owl:Class	
GO:0036483	biolink:NamedThing	neuron intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress	A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a neuron. The pathway is induced in response to a stimulus indicating endoplasmic reticulum (ER) stress, and ends when the execution phase of apoptosis is triggered. ER stress usually results from the accumulation of unfolded or misfolded proteins in the ER lumen.	tmpzr1t_l9r_go_relaxed.owl	ER stress-induced neuron intrinsic apoptotic signaling pathway|ER stress-induced neuron apoptosis|endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway|endoplasmic reticulum stress-induced neuron apoptosis							bf	2014-08-14T13:33:23Z					biological_process											owl:Class	
GO:0003037	biolink:NamedThing	detection of pH by carotid body chemoreceptor signaling	The process in which information about the levels of hydrogen ions are received and are converted to a molecular signal by chemoreceptors in a carotid body.	tmpzr1t_l9r_go_relaxed.owl	detection of pH by carotid body chemoreceptor signalling													biological_process											owl:Class	
GO:0003029	biolink:NamedThing	detection of hypoxic conditions in blood by carotid body chemoreceptor signaling	The process in which information about a lack of oxygen are received and are converted to a molecular signal by chemoreceptors in the carotid bodies.	tmpzr1t_l9r_go_relaxed.owl	detection of hypoxic conditions in blood by carotid body chemoreceptor signalling													biological_process											owl:Class	
GO:0030422	biolink:NamedThing	production of siRNA involved in RNA interference	Cleavage of double-stranded RNA to form small interfering RNA molecules (siRNAs) of 21-23 nucleotides, in the context of RNA interference.	tmpzr1t_l9r_go_relaxed.owl	RNA interference, production of guide RNAs|production of guide RNAs involved in RNA interference|RNA interference, production of siRNA													biological_process											owl:Class	
GO:0031641	biolink:NamedThing	regulation of myelination	Any process that modulates the frequency, rate or extent of the formation of a myelin sheath around nerve axons.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0070460	biolink:NamedThing	thyroid-stimulating hormone secretion	The regulated release of thyroid-stimulating hormone, a peptide hormone that stimulates the activity of the thyroid gland, from secretory granules in the anterior pituitary.	tmpzr1t_l9r_go_relaxed.owl	TSH secretion|thyroid stimulating hormone secretion													biological_process											owl:Class	
GO:1905306	biolink:NamedThing	positive regulation of cardiac myofibril assembly	Any process that activates or increases the frequency, rate or extent of cardiac myofibril assembly.	tmpzr1t_l9r_go_relaxed.owl	activation of cardiac myofibril assembly|up-regulation of heart myofibril assembly|up regulation of heart myofibril assembly|positive regulation of cardiac myofibril development|activation of cardiac myofibril morphogenesis|up-regulation of cardiac myofibril assembly|up regulation of cardiac myofibril assembly|upregulation of cardiac myofibril assembly|positive regulation of cardiac myofibril morphogenesis|up-regulation of cardiac myofibril development|upregulation of cardiac myofibril morphogenesis|up-regulation of cardiac myofibril morphogenesis|upregulation of heart myofibril assembly|upregulation of cardiac myofibril development|up regulation of cardiac myofibril development|activation of cardiac myofibril development|up regulation of cardiac myofibril morphogenesis|positive regulation of heart myofibril assembly|activation of heart myofibril assembly							rl	2016-07-06T10:02:07Z					biological_process											owl:Class	
GO:0140396	biolink:NamedThing	5'-hydroxyaverantin dehydrogenase activity	Catalyzes the reaction: (1'S,5'S)-hydroxyaverantin + NAD(+) <=> 5'-oxoaverantin + NADH.	tmpzr1t_l9r_go_relaxed.owl					RHEA:35475|EC:1.1.1.352			pg	2019-11-29T08:56:49Z					molecular_function											owl:Class	
GO:2000144	biolink:NamedThing	positive regulation of DNA-templated transcription, initiation	Any process that activates or increases the frequency, rate or extent of DNA-templated transcription initiation.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of initiation of DNA-dependent transcription|positive regulation of transcription initiation, DNA-dependent|transcriptional transactivation|positive regulation of DNA-dependent transcription, initiation|transactivation							mah	2010-10-01T09:11:43Z					biological_process											owl:Class	
GO:0070413	biolink:NamedThing	trehalose metabolism in response to stress	The chemical reactions and pathways involving trehalose that occur as a result of a stimulus indicating the organism is under stress.	tmpzr1t_l9r_go_relaxed.owl	trehalose metabolic process involved in response to stress													biological_process											owl:Class	
GO:0035143	biolink:NamedThing	caudal fin morphogenesis	The process in which the anatomical structures of the caudal fin are generated and organized. A caudal fin is an unpaired medial fin mounted at the caudal end of the fish, and is the main fin used for propulsion.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1902102	biolink:NamedThing	regulation of metaphase/anaphase transition of meiotic cell cycle	Any process that modulates the frequency, rate or extent of metaphase/anaphase transition of meiotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl	regulation of meiotic metaphase/anaphase transition							jl	2013-05-02T12:45:38Z					biological_process											owl:Class	
GO:0021512	biolink:NamedThing	spinal cord anterior/posterior patterning	The process that regulates the coordinated growth and differentiation that establishes the non-random anterior-posterior spatial arrangement of the spinal cord.	tmpzr1t_l9r_go_relaxed.owl	spinal cord anterior-posterior patterning|spinal cord rostrocaudal patterning													biological_process											owl:Class	
GO:0021511	biolink:NamedThing	spinal cord patterning	The regionalization process that regulates the coordinated growth and establishes the non-random spatial arrangement of the spinal cord.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0021591	biolink:NamedThing	ventricular system development	The process whose specific outcome is the progression of the brain ventricular system over time, from its formation to the mature structure. The brain ventricular system consists of four communicating cavities within the brain that are continuous with the central canal of the spinal cord. These cavities include two lateral ventricles, the third ventricle and the fourth ventricle. Cerebrospinal fluid fills the ventricles and is produced by the choroid plexus.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0021560	biolink:NamedThing	abducens nerve development	The process whose specific outcome is the progression of the abducens nerve over time, from its formation to the mature structure. The motor function of the abducens nerve is to contract the lateral rectus which results in abduction of the eye.	tmpzr1t_l9r_go_relaxed.owl	CN VI development|cranial nerve 6 development|cranial nerve VI development													biological_process											owl:Class	
GO:0060185	biolink:NamedThing	outer ear unfolding	The opening and spreading out of the outer ear.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0042473	biolink:NamedThing	outer ear morphogenesis	The process in which the anatomical structures of the outer ear are generated and organized. The outer ear is the part of the ear external to the tympanum (eardrum). It consists of a tube (the external auditory meatus) that directs sound waves on to the tympanum, and may also include the external pinna, which extends beyond the skull.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0036252	biolink:NamedThing	positive regulation of transcription from RNA polymerase II promoter in response to menadione	Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a menadione stimulus. Menadione (also called vitamin K3) is a naphthoquinone having a methyl substituent at the 2-position.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of transcription from RNA polymerase II promoter in response to menadione stress							bf	2012-06-12T11:40:58Z					biological_process											owl:Class	
GO:0036245	biolink:NamedThing	cellular response to menadione	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a menadione stimulus. Menadione (also called vitamin K3) is a naphthoquinone having a methyl substituent at the 2-position.	tmpzr1t_l9r_go_relaxed.owl	cellular response to vitamin K3							bf	2012-05-28T10:23:02Z					biological_process											owl:Class	
GO:0034658	biolink:NamedThing	isopropylmalate transmembrane transporter activity	Enables the transfer of isopropylmalate from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0021502	biolink:NamedThing	neural fold elevation formation	The process in which the lateral borders of the neural plate begin to migrate upwards to form the neural folds, caused by the proliferation of the underlying mesoderm.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0001536	biolink:NamedThing	radial spoke stalk	Globular portion of the radial spoke that projects towards the central pair of microtubules.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0001534	biolink:NamedThing	radial spoke	Protein complex that links the outer microtubule doublet of the ciliary or flagellum axoneme with the sheath that surrounds the central pair of microtubules. Composed of a stalk that attaches to each doublet microtubule and a globular structure (spoke head) that projects toward the central pair of microtubules.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Radial_spoke									cellular_component											owl:Class	
GO:0015545	biolink:NamedThing	bicyclomycin transmembrane transporter activity	Enables the transfer of bicyclomycin from one side of a membrane to the other. Bicyclomycin (or bicozamycin) is an antibacterial drug often used as a livestock feed additive.	tmpzr1t_l9r_go_relaxed.owl	bicyclomycin transporter activity|bicyclomycin/sulfathiazole:hydrogen antiporter activity													molecular_function											owl:Class	
GO:0015905	biolink:NamedThing	bicyclomycin transmembrane transport	The directed movement of bicyclomycin across a lipid bilayer, from one side of a membrane to the other. Bicyclomycin (or bicozamycin) is an antibacterial drug often used as a livestock feed additive.	tmpzr1t_l9r_go_relaxed.owl	bicyclomycin transport													biological_process											owl:Class	
GO:1904087	biolink:NamedThing	negative regulation of epiboly involved in gastrulation with mouth forming second	Any process that stops, prevents or reduces the frequency, rate or extent of epiboly involved in gastrulation with mouth forming second.	tmpzr1t_l9r_go_relaxed.owl	downregulation of epiboly involved in gastrulation with mouth forming second|down-regulation of epiboly involved in gastrulation with mouth forming second|inhibition of epiboly involved in gastrulation with mouth forming second|down regulation of epiboly involved in gastrulation with mouth forming second							dos	2015-03-25T11:17:41Z					biological_process											owl:Class	
GO:0008587	biolink:NamedThing	imaginal disc-derived wing margin morphogenesis	The process in which the anatomical structures of the imaginal disc-derived wing margin are generated and organized. The wing margin is a strip of cells in the third instar disc at the boundary between the presumptive dorsal and ventral surfaces of the wing blade.	tmpzr1t_l9r_go_relaxed.owl	wing margin morphogenesis					See also the fly_anatomy.ontology term 'wing margin ; FBbt:00005378'.								biological_process											owl:Class	
GO:1903615	biolink:NamedThing	positive regulation of protein tyrosine phosphatase activity	Any process that activates or increases the frequency, rate or extent of protein tyrosine phosphatase activity.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of tyrosine O-phosphate phosphatase activity|activation of [phosphotyrosine]protein phosphatase activity|up regulation of protein tyrosine phosphatase activity|positive regulation of tyrosylprotein phosphatase activity|up regulation of protein-tyrosine-phosphatase activity|upregulation of protein-tyrosine-phosphate phosphohydrolase activity|activation of PTP-phosphatase activity|upregulation of phosphotyrosine phosphatase activity|upregulation of PTPase activity|activation of phosphotyrosylprotein phosphatase activity|positive regulation of protein phosphotyrosine phosphatase activity|up-regulation of [phosphotyrosine]protein phosphatase activity|up-regulation of tyrosine O-phosphate phosphatase activity|upregulation of [phosphotyrosine]protein phosphatase activity|up regulation of protein phosphotyrosine phosphatase activity|up-regulation of phosphoprotein phosphatase (phosphotyrosine) activity|up regulation of [phosphotyrosine]protein phosphatase activity|activation of protein tyrosine phosphatase activity|positive regulation of phosphotyrosine histone phosphatase activity|positive regulation of PTPase activity|up-regulation of PTP-phosphatase activity|up-regulation of PTPase activity|upregulation of protein-tyrosine-phosphatase activity|positive regulation of phosphotyrosine phosphatase activity|activation of phosphotyrosine protein phosphatase activity|up regulation of phosphotyrosine phosphatase activity|activation of tyrosylprotein phosphatase activity|up-regulation of tyrosylprotein phosphatase activity|positive regulation of protein-tyrosine-phosphate phosphohydrolase activity|up regulation of PTP-phosphatase activity|upregulation of phosphoprotein phosphatase (phosphotyrosine) activity|up-regulation of phosphotyrosylprotein phosphatase activity|activation of tyrosine O-phosphate phosphatase activity|activation of phosphotyrosine phosphatase activity|up regulation of tyrosylprotein phosphatase activity|up-regulation of protein-tyrosine-phosphatase activity|activation of protein phosphotyrosine phosphatase activity|up-regulation of protein phosphotyrosine phosphatase activity|upregulation of tyrosine O-phosphate phosphatase activity|positive regulation of phosphotyrosine protein phosphatase activity|upregulation of phosphotyrosine protein phosphatase activity|upregulation of phosphotyrosine histone phosphatase activity|activation of protein-tyrosine-phosphate phosphohydrolase activity|positive regulation of [phosphotyrosine]protein phosphatase activity|upregulation of protein phosphotyrosine phosphatase activity|up regulation of PTPase activity|activation of PTPase activity|positive regulation of PPT-phosphatase activity|positive regulation of phosphotyrosylprotein phosphatase activity|up-regulation of protein tyrosine phosphatase activity|up regulation of PPT-phosphatase activity|up-regulation of phosphotyrosine phosphatase activity|positive regulation of protein-tyrosine-phosphatase activity|up regulation of phosphoprotein phosphatase (phosphotyrosine) activity|upregulation of protein tyrosine phosphatase activity|up-regulation of protein-tyrosine-phosphate phosphohydrolase activity|upregulation of tyrosylprotein phosphatase activity|up regulation of tyrosine O-phosphate phosphatase activity|activation of PPT-phosphatase activity|up-regulation of phosphotyrosine histone phosphatase activity|positive regulation of PTP-phosphatase activity|up-regulation of PPT-phosphatase activity|up regulation of protein-tyrosine-phosphate phosphohydrolase activity|activation of protein-tyrosine-phosphatase activity|upregulation of phosphotyrosylprotein phosphatase activity|positive regulation of phosphoprotein phosphatase (phosphotyrosine) activity|upregulation of PTP-phosphatase activity|activation of phosphoprotein phosphatase (phosphotyrosine) activity|up regulation of phosphotyrosylprotein phosphatase activity|up regulation of phosphotyrosine histone phosphatase activity|activation of phosphotyrosine histone phosphatase activity|up regulation of phosphotyrosine protein phosphatase activity|upregulation of PPT-phosphatase activity|up-regulation of phosphotyrosine protein phosphatase activity							sl	2014-11-18T01:11:55Z					biological_process											owl:Class	
GO:1901985	biolink:NamedThing	positive regulation of protein acetylation	Any process that activates or increases the frequency, rate or extent of protein acetylation.	tmpzr1t_l9r_go_relaxed.owl	upregulation of protein acetylation|positive regulation of protein amino acid acetylation|upregulation of protein amino acid acetylation|activation of protein amino acid acetylation|activation of protein acetylation|up regulation of protein amino acid acetylation|up regulation of protein acetylation|up-regulation of protein amino acid acetylation|up-regulation of protein acetylation							ss	2013-03-14T00:40:19Z					biological_process											owl:Class	
GO:0060830	biolink:NamedThing	ciliary receptor clustering involved in smoothened signaling pathway	Grouping of smoothened or patched receptors in a cilium, contributing to the smoothened signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	ciliary receptor clustering involved in hedgehog signaling pathway|ciliary receptor clustering involved in smoothened signalling pathway|ciliary receptor clustering involved in hh signaling pathway							dph	2009-08-11T02:06:33Z					biological_process											owl:Class	
GO:1905524	biolink:NamedThing	negative regulation of protein autoubiquitination	Any process that stops, prevents or reduces the frequency, rate or extent of protein autoubiquitination.	tmpzr1t_l9r_go_relaxed.owl	down regulation of protein auto-ubiquitinylation|down regulation of protein self-ubiquitinylation|down regulation of protein auto-ubiquitination|down regulation of protein autoubiquitination|down regulation of protein autoubiquitinylation|downregulation of protein auto-ubiquitinylation|negative regulation of protein self-ubiquitinylation|downregulation of protein auto-ubiquitination|negative regulation of protein autoubiquitinylation|downregulation of protein autoubiquitinylation|inhibition of protein autoubiquitinylation|down-regulation of protein autoubiquitinylation|down-regulation of protein autoubiquitination|negative regulation of protein auto-ubiquitination|downregulation of protein self-ubiquitinylation|inhibition of protein auto-ubiquitinylation|down-regulation of protein auto-ubiquitinylation|inhibition of protein autoubiquitination|downregulation of protein autoubiquitination|inhibition of protein auto-ubiquitination|negative regulation of protein self-ubiquitination|inhibition of protein self-ubiquitinylation|downregulation of protein self-ubiquitination|negative regulation of protein auto-ubiquitinylation|down regulation of protein self-ubiquitination|inhibition of protein self-ubiquitination|down-regulation of protein self-ubiquitinylation|down-regulation of protein self-ubiquitination|down-regulation of protein auto-ubiquitination							bc	2016-10-04T10:53:25Z					biological_process											owl:Class	
GO:0051865	biolink:NamedThing	protein autoubiquitination	The ubiquitination by a protein of one or more of its own amino acid residues, or residues on an identical protein. Ubiquitination occurs on the lysine residue by formation of an isopeptide crosslink.	tmpzr1t_l9r_go_relaxed.owl	protein auto-ubiquitination|protein self-ubiquitinylation|protein autoubiquitinylation|protein self-ubiquitination|protein auto-ubiquitinylation													biological_process											owl:Class	
GO:0061046	biolink:NamedThing	regulation of branching involved in lung morphogenesis	Any process that modulates the rate, frequency, or extent of the process in which a highly ordered sequence of patterning events generates the branched structures of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-02-25T10:41:38Z					biological_process											owl:Class	
GO:0098512	biolink:NamedThing	detection of humidity stimulus involved in sensory perception	The series of events in which a humidity stimulus is received and converted into a molecular signal as part of the sensory perception of humidity.	tmpzr1t_l9r_go_relaxed.owl								dos	2013-09-25T14:09:25Z					biological_process											owl:Class	
GO:0098509	biolink:NamedThing	sensory perception of humidity	The series of events required for an organism to detect some level of humidity in its environment, convert this detection into a molecular signal, and recognize and characterize the signal. This is a neurological process.	tmpzr1t_l9r_go_relaxed.owl	hygrosensory perception					Note, this is not classified under 'detection of chemical stimulus' as there are various potential mechanisms of hygroperception including detection of mechanical stimulus.		dos	2013-09-25T13:52:27Z					biological_process											owl:Class	
GO:0007282	biolink:NamedThing	cystoblast division	Any of the rounds of incomplete mitosis undergone by a cystoblast to form a cyst of interconnected cells.	tmpzr1t_l9r_go_relaxed.owl	cystoblast cell division													biological_process											owl:Class	
GO:0086048	biolink:NamedThing	membrane depolarization during bundle of His cell action potential	The process in which bundle of His cardiac muscle cell membrane potential changes in the depolarizing direction from the negative resting potential towards the positive membrane potential that will be the peak of the action potential.	tmpzr1t_l9r_go_relaxed.owl	membrane depolarization during bundle of His cardiac muscle cell action potential							dph	2011-11-16T10:56:26Z					biological_process											owl:Class	
GO:0097735	biolink:NamedThing	DIM/DIP cell wall layer	A section of the Actinobacterium-type cell wall composed of (phenyl)phthiocerol, phthiodiolone, phthiotriol dimycocerosate, diphthioceranate and other compounds.	tmpzr1t_l9r_go_relaxed.owl								pr	2016-10-05T14:55:30Z					cellular_component											owl:Class	
GO:0009275	biolink:NamedThing	Gram-positive-bacterium-type cell wall	A layer of peptidoglycan found outside of the cytoplasmic membrane. The peptidoglycan is relatively thick (20-80nm) and retains the primary stain of the Gram procedure, thus cells appear blue after Gram stain. The cell walls often contain teichoic acids (acidic anionic polysaccharides) bound to the peptidoglycan. Examples of this component are found in Gram-positive bacteria.	tmpzr1t_l9r_go_relaxed.owl	cell wall of Gram-positive Bacteria|20-80nm peptidoglycan-based cell wall													cellular_component											owl:Class	
GO:1903885	biolink:NamedThing	negative regulation of chemokine (C-C motif) ligand 20 production	Any process that stops, prevents or reduces the frequency, rate or extent of chemokine (C-C motif) ligand 20 production.	tmpzr1t_l9r_go_relaxed.owl	down regulation of CCL-20 production|negative regulation of CCL-20 production|inhibition of CCL20 production|inhibition of CCL-20 production|downregulation of chemokine (C-C motif) ligand 20 production|downregulation of CCL20 production|down regulation of C-C motif chemokine 20 production|down regulation of CCL20 production|inhibition of chemokine (C-C motif) ligand 20 production|down-regulation of chemokine (C-C motif) ligand 20 production|downregulation of CCL-20 production|negative regulation of C-C motif chemokine 20 production|downregulation of C-C motif chemokine 20 production|inhibition of C-C motif chemokine 20 production|negative regulation of CCL20 production|down regulation of chemokine (C-C motif) ligand 20 production|down-regulation of CCL-20 production|down-regulation of C-C motif chemokine 20 production|down-regulation of CCL20 production							krc	2015-02-06T16:31:11Z					biological_process											owl:Class	
GO:0036392	biolink:NamedThing	chemokine (C-C motif) ligand 20 production	The appearance of chemokine (C-C motif) ligand 20 (CCL20) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	tmpzr1t_l9r_go_relaxed.owl	CCL-20 production|C-C motif chemokine 20 production|CCL20 production							bf	2013-06-17T14:42:07Z					biological_process											owl:Class	
GO:0006362	biolink:NamedThing	transcription elongation from RNA polymerase I promoter	The extension of an RNA molecule after transcription initiation and promoter clearance at an RNA polymerase I specific promoter by the addition of ribonucleotides catalyzed by RNA polymerase I.	tmpzr1t_l9r_go_relaxed.owl	RNA elongation from Pol I promoter|RNA polymerase I transcription elongation factor activity													biological_process											owl:Class	
GO:1990950	biolink:NamedThing	metaphase/anaphase transition of meiosis II	The cell cycle process in which a cell progresses from metaphase to anaphase as part of meiosis II.	tmpzr1t_l9r_go_relaxed.owl	second meiotic metaphase/anaphase transition|meiosis II metaphase/anaphase transition							mah	2016-04-25T15:28:51Z					biological_process											owl:Class	
GO:1904416	biolink:NamedThing	negative regulation of xenophagy	Any process that stops, prevents or reduces the frequency, rate or extent of xenophagy.	tmpzr1t_l9r_go_relaxed.owl	inhibition of xenophagy|down-regulation of xenophagy|down regulation of xenophagy|downregulation of xenophagy					An example of this is mouse Tbk1 (UniProt symbol, Q9WUN2) in PMID:21617041 (inferred from mutant phenotype).		pad	2015-06-29T12:30:53Z					biological_process											owl:Class	
GO:0098792	biolink:NamedThing	xenophagy	The selective autophagy process in which a region of cytoplasm containing an intracellular pathogen or some part of an intracellular pathogen (e.g. viral capsid) is enclosed in a double membrane bound autophagosome, which then fuses with the lysosome leading to degradation of the contents.	tmpzr1t_l9r_go_relaxed.owl						While making xenophagy a subclass of (macro)autophagy may seem to directly contradict the definition of autophagy (literally self eating), it is clear that the same pathway is involved as in macroautophagy that doesn't target foreign material: formation of double-membrane-bounded autophagosomes that enclose a region of cytoplasm for degradation.								biological_process											owl:Class	
GO:0052314	biolink:NamedThing	phytoalexin metabolic process	The chemical reactions and pathways involving phytoalexins, any of a range of substances produced by plants as part of their defense response.	tmpzr1t_l9r_go_relaxed.owl	phytoalexin metabolism													biological_process											owl:Class	
GO:0030901	biolink:NamedThing	midbrain development	The process whose specific outcome is the progression of the midbrain over time, from its formation to the mature structure. The midbrain is the middle division of the three primary divisions of the developing chordate brain or the corresponding part of the adult brain (in vertebrates, includes a ventral part containing the cerebral peduncles and a dorsal tectum containing the corpora quadrigemina and that surrounds the aqueduct of Sylvius connecting the third and fourth ventricles).	tmpzr1t_l9r_go_relaxed.owl	mesencephalon development													biological_process											owl:Class	
GO:0030501	biolink:NamedThing	positive regulation of bone mineralization	Any process that activates or increases the frequency, rate or extent of bone mineralization.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of bone mineralization|up regulation of bone mineralization|activation of bone mineralization|upregulation of bone mineralization|stimulation of bone mineralization													biological_process											owl:Class	
GO:0075247	biolink:NamedThing	aeciospore formation	The process in which a dikaryotic spore of typically a rust fungus is produced in an aecium; in heteroecious rusts, the aeciospore is a spore stage that infects the alternate host.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0061400	biolink:NamedThing	positive regulation of transcription from RNA polymerase II promoter in response to calcium ion	Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter in response to a calcium ion stimulus.	tmpzr1t_l9r_go_relaxed.owl								dph	2012-01-10T09:36:02Z					biological_process											owl:Class	
GO:0071277	biolink:NamedThing	cellular response to calcium ion	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a calcium ion stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to Ca2+ ion							mah	2009-12-10T03:55:01Z					biological_process											owl:Class	
GO:0015499	biolink:NamedThing	formate transmembrane transporter activity	Enables the transfer of formate from one side of a membrane to the other. Formate is also known as methanoate, the anion HCOO- derived from methanoic (formic) acid.	tmpzr1t_l9r_go_relaxed.owl	formate uptake permease activity|formate uptake transmembrane transporter activity				RHEA:29679							GO:0015659		molecular_function											owl:Class	
GO:0033030	biolink:NamedThing	negative regulation of neutrophil apoptotic process	Any process that stops, prevents, or reduces the frequency, rate, or extent of neutrophil apoptotic process.	tmpzr1t_l9r_go_relaxed.owl	inhibition of neutrophil apoptosis|negative regulation of neutrophil apoptosis|down-regulation of neutrophil apoptosis|downregulation of neutrophil apoptosis|down regulation of neutrophil apoptosis													biological_process											owl:Class	
GO:0001781	biolink:NamedThing	neutrophil apoptotic process	Any apoptotic process in a neutrophil, any of the immature or mature forms of a granular leukocyte that in its mature form has a nucleus with three to five lobes connected by slender threads of chromatin, and cytoplasm containing fine inconspicuous granules and stainable by neutral dyes.	tmpzr1t_l9r_go_relaxed.owl	programmed cell death of neutrophils by apoptosis|neutrophil apoptosis|neutrophil programmed cell death by apoptosis|apoptosis of neutrophils|programmed cell death, neutrophils													biological_process											owl:Class	
GO:0032937	biolink:NamedThing	SREBP-SCAP-Insig complex	A protein complex formed by the association of sterol regulatory element binding protein (SREBP), SREBP-cleavage-activating protein (SCAP), and an Insig protein (Insig-1 or Insig-2) in the ER membrane.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0090520	biolink:NamedThing	sphingolipid mediated signaling pathway	A series of molecular signals mediated by a sphingolipid.	tmpzr1t_l9r_go_relaxed.owl	sphingolipid signaling pathway|sphingolipid-mediated signaling pathway|sphingosine signaling pathway|ceramide signaling pathway|sphingolipid mediated signal transduction|ceramide 1-phosphate signaling pathway							tb	2013-01-08T09:30:54Z					biological_process											owl:Class	
GO:0043675	biolink:NamedThing	sculpture element	The third layer of the sexine.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0060105	biolink:NamedThing	epicuticle of collagen and cuticulin-based cuticle extracellular matrix	A lipid-containing layer of cuticle that lies between the cortical layer and the surface coat. An example of this component is found in Caenorhabditis elegans.	tmpzr1t_l9r_go_relaxed.owl	epicuticle of collagen and cuticulin-based exoskeleton extracellular matrix													cellular_component											owl:Class	
GO:0048913	biolink:NamedThing	anterior lateral line nerve glial cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a glial cell in the anterior lateral line nerve.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0014028	biolink:NamedThing	notochord formation	The formation of the notochord from the chordamesoderm. The notochord is composed of large cells packed within a firm connective tissue sheath and is found in all chordates at the ventral surface of the neural tube. In vertebrates, the notochord contributes to the vertebral column.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0140511	biolink:NamedThing	mitotic nuclear bridge stalk	Either of the regions of a mitotic nuclear bridge proximal to the main portion of each daughter nucleus. The nuclear envelope in the stalk regions is depleted of nuclear pore complexes.	tmpzr1t_l9r_go_relaxed.owl								pg	2020-09-07T10:06:23Z					cellular_component											owl:Class	
GO:0009556	biolink:NamedThing	microsporogenesis	The process in which the microsporocyte undergoes meiosis, giving rise to four haploid microspores.	tmpzr1t_l9r_go_relaxed.owl	microspore development													biological_process											owl:Class	
GO:0031298	biolink:NamedThing	replication fork protection complex	A protein complex conserved in eukaryotes and associated with the replication fork; the complex stabilizes stalled replication forks and is thought to be involved in coordinating leading- and lagging-strand synthesis and in replication checkpoint signaling.	tmpzr1t_l9r_go_relaxed.owl	Swi1-Swi3 complex|TIMELESS-TIPIN complex|replisome progression complex													cellular_component											owl:Class	
GO:0043596	biolink:NamedThing	nuclear replication fork	The Y-shaped region of a nuclear replicating DNA molecule, resulting from the separation of the DNA strands and in which the synthesis of new strands takes place. Also includes associated protein complexes.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0010578	biolink:NamedThing	regulation of adenylate cyclase activity involved in G protein-coupled receptor signaling pathway	Any process that modulates the frequency, rate or extent of adenylate cyclase (AC) activity that is an integral part of a G protein-coupled receptor signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	regulation of adenylate cyclase activity involved in G-protein signaling pathway|regulation of adenylate cyclase activity involved in G-protein signalling|regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway													biological_process											owl:Class	
GO:0007188	biolink:NamedThing	adenylate cyclase-modulating G protein-coupled receptor signaling pathway	The series of molecular signals generated as a consequence of a G protein-coupled receptor binding to its physiological ligand, where the pathway proceeds through activation or inhibition of adenylyl cyclase activity and a subsequent change in the concentration of cyclic AMP (cAMP).	tmpzr1t_l9r_go_relaxed.owl	G protein signaling, coupled to cAMP nucleotide second messenger|G-protein signalling, coupled to cAMP nucleotide second messenger|G protein signaling, coupled to cyclic AMP nucleotide second messenger|G-protein signaling, coupled to cyclic AMP nucleotide second messenger|G protein signalling, coupled to cAMP nucleotide second messenger|G-protein signalling, coupled to cyclic AMP nucleotide second messenger|G protein signalling, coupled to cyclic AMP nucleotide second messenger|GPCR signaling pathway via cAMP second messenger|adenylate cyclase-modulating GPCR signaling pathway|G-protein signaling, coupled to cAMP nucleotide second messenger|GPCR signaling pathway via modulation of adenylate cyclase activity					This term is intended to cover steps in a GPCR signaling pathway both upstream and downstream of adenylate-cyclase activity. For steps upstream of adenylate cyclase activity, consider instead annotating to 'regulation of adenylate cyclase activity involved in G protein-coupled receptor signaling pathway ; GO:0010578.								biological_process											owl:Class	
GO:0042713	biolink:NamedThing	sperm ejaculation	The expulsion of seminal fluid, thick white fluid containing spermatozoa, from the male genital tract.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0070074	biolink:NamedThing	mononeme	A secretory organelle that forms part of the apical complex; a small, threadlike structure located is close proximity to the subpellicular microtubules. Its contents include a rhomboid protease (PfROM1 in Plasmodium falciparum) that moves from the lateral asymmetric localization to the merozoite apical pole and the posterior pole upon release of merozoites from schizonts.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:2000597	biolink:NamedThing	positive regulation of optic nerve formation	Any process that activates or increases the frequency, rate or extent of optic nerve formation.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of CN II biosynthesis|positive regulation of CN II formation							yaf	2011-04-11T03:41:39Z					biological_process											owl:Class	
GO:0021634	biolink:NamedThing	optic nerve formation	The process that gives rise to the optic nerve. This process pertains to the initial formation of a structure from unspecified parts. The sensory optic nerve originates from the bipolar cells of the retina and conducts visual information to the brainstem. The optic nerve exits the back of the eye in the orbit, enters the optic canal, and enters the central nervous system at the optic chiasm (crossing) where the nerve fibers become the optic tract just prior to entering the hindbrain.	tmpzr1t_l9r_go_relaxed.owl	CN II formation|CN II biosynthesis													biological_process											owl:Class	
GO:0043276	biolink:NamedThing	anoikis	Apoptosis triggered by inadequate or inappropriate adherence to substrate e.g. after disruption of the interactions between normal epithelial cells and the extracellular matrix.	tmpzr1t_l9r_go_relaxed.owl	suspension induced apoptosis|detachment induced cell death				Wikipedia:Anoikis									biological_process											owl:Class	
GO:0075266	biolink:NamedThing	negative regulation of oogonium development	Any process that stops, prevents, or reduces the frequency, rate or extent of oogonium development, a process that leads to the formation of a female gametangium of oomycetes, containing one or more gametes.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0061846	biolink:NamedThing	dendritic spine cytoplasm	The region of the neuronal cytoplasm located in dendritic spines.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0002614	biolink:NamedThing	negative regulation of monocyte antigen processing and presentation	Any process that stops, prevents, or reduces the frequency, rate, or extent of monocyte antigen processing and presentation.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of monocyte antigen processing and presentation|inhibition of monocyte antigen processing and presentation|down regulation of monocyte antigen processing and presentation|downregulation of monocyte antigen processing and presentation													biological_process											owl:Class	
GO:0002471	biolink:NamedThing	monocyte antigen processing and presentation	The process in which a monocyte expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0005674	biolink:NamedThing	transcription factor TFIIF complex	A general transcription initiation factor which in humans consists of a heterodimer of an alpha and a beta subunit. Helps recruit RNA polymerase II to the initiation complex and promotes translation elongation.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0032429	biolink:NamedThing	regulation of phospholipase A2 activity	Any process that modulates the activity of the enzyme phospholipase A2.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0009548	biolink:NamedThing	plasmodesmatal plasma membrane	The portion of the plasma membrane surrounding a plasmodesma.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:1903434	biolink:NamedThing	negative regulation of constitutive secretory pathway	Any process that stops, prevents or reduces the frequency, rate or extent of constitutive secretory pathway.	tmpzr1t_l9r_go_relaxed.owl	down regulation of constitutive secretory pathway|inhibition of constitutive secretory pathway|down-regulation of constitutive secretory pathway|downregulation of constitutive secretory pathway							als	2014-09-15T15:07:40Z					biological_process											owl:Class	
GO:0045054	biolink:NamedThing	constitutive secretory pathway	A process of exocytosis found in all eukaryotic cells, in which transport vesicles destined for the plasma membrane leave the trans-Golgi network in a steady stream. Upon exocytosis, the membrane proteins and lipids in these vesicles provide new components for the plasma membrane, and the soluble proteins inside the vesicles are released into the extracellular space.	tmpzr1t_l9r_go_relaxed.owl	constitutive exocytosis													biological_process											owl:Class	
GO:0090279	biolink:NamedThing	regulation of calcium ion import	Any process that modulates the rate, frequency, or extent of the directed movement of calcium ions into a cell or organelle.	tmpzr1t_l9r_go_relaxed.owl	regulation of transmembrane calcium influx							tb	2010-02-08T05:11:20Z					biological_process											owl:Class	
GO:1901375	biolink:NamedThing	acetate ester transmembrane transporter activity	Enables the transfer of an acetate ester from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl								bf	2012-09-28T10:47:08Z					molecular_function											owl:Class	
GO:1901584	biolink:NamedThing	tetrapeptide transmembrane transporter activity	Enables the transfer of tetrapeptide from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-11-06T15:40:10Z					molecular_function											owl:Class	
GO:1901583	biolink:NamedThing	tetrapeptide transmembrane transport	The directed movement of tetrapeptide across a membrane.	tmpzr1t_l9r_go_relaxed.owl	tetrapeptide membrane transport					Note that this term is not intended for use in annotating lateral movement within membranes.		jl	2012-11-06T15:40:02Z					biological_process											owl:Class	
GO:0002177	biolink:NamedThing	manchette	A tubular array of microtubules that extends from the perinuclear ring surrounding the spermatid nucleus to the flagellar axoneme. The manchette may also contain F-actin filaments.	tmpzr1t_l9r_go_relaxed.owl								hjd	2010-12-01T02:31:43Z					cellular_component											owl:Class	
GO:0048403	biolink:NamedThing	brain-derived neurotrophic factor binding	Binding to brain-derived neurotrophic factor.	tmpzr1t_l9r_go_relaxed.owl	neurotrophin TRKB receptor activity|BDNF binding													molecular_function											owl:Class	
GO:0051190	biolink:NamedThing	prosthetic group catabolic process	The chemical reactions and pathways resulting in the breakdown of a prosthetic group, the non-amino acid portion of certain protein molecules. Prosthetic groups may be inorganic or organic and are usually required for the biological activity of the protein.	tmpzr1t_l9r_go_relaxed.owl	prosthetic group degradation|prosthetic group breakdown|coenzyme and prosthetic group catabolism|coenzyme and prosthetic group catabolic process|prosthetic group catabolism													biological_process											owl:Class	
GO:0010787	biolink:NamedThing	COPI coating of Golgi vesicle, inter-Golgi cisterna	The addition of COPI proteins and adaptor proteins to Golgi membranes during the formation of inter-Golgi cisterna transport vesicles, forming a vesicle coat.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0110116	biolink:NamedThing	regulation of compound eye photoreceptor cell differentiation	Any process that modulates the frequency, rate or extent of compound eye photoreceptor cell differentiation.	tmpzr1t_l9r_go_relaxed.owl								kmv	2018-07-16T18:08:49Z					biological_process											owl:Class	
GO:1905418	biolink:NamedThing	positive regulation of amoeboid sperm motility	Any process that activates or increases the frequency, rate or extent of amoeboid sperm motility.	tmpzr1t_l9r_go_relaxed.owl	activation of amoeboid sperm movement|activation of ameboid sperm movement|upregulation of amoeboid sperm movement|up-regulation of amoeboid sperm movement|activation of ameboid sperm motility|upregulation of ameboid sperm movement|up regulation of ameboid sperm motility|positive regulation of ameboid sperm motility|upregulation of ameboid sperm motility|up-regulation of amoeboid sperm motility|up regulation of amoeboid sperm movement|positive regulation of amoeboid sperm movement|up-regulation of ameboid sperm motility|up-regulation of ameboid sperm movement|activation of amoeboid sperm motility|up regulation of amoeboid sperm motility|up regulation of ameboid sperm movement|upregulation of amoeboid sperm motility|positive regulation of ameboid sperm movement							pr	2016-09-01T11:29:03Z					biological_process											owl:Class	
GO:0035506	biolink:NamedThing	negative regulation of myosin light chain kinase activity	Any process that stops, prevents, or reduces the frequency, rate or extent of myosin light chain kinase activity.	tmpzr1t_l9r_go_relaxed.owl								bf	2010-04-30T10:49:21Z					biological_process											owl:Class	
GO:0004687	biolink:NamedThing	myosin light chain kinase activity	Catalysis of the reaction: ATP + myosin-light-chain = ADP + myosin-light-chain phosphate.	tmpzr1t_l9r_go_relaxed.owl	myosin light-chain kinase (phosphorylating)|myosin light-chain kinase (phosphorylating) activity|myosin light-chain kinase activity|MLCkase activity|ATP:myosin-light-chain O-phosphotransferase|ATP:myosin-light-chain O-phosphotransferase activity|calcium/calmodulin-dependent myosin light chain kinase activity|myosin light-chain kinase|smooth-muscle-myosin-light-chain kinase activity|myosin light chain protein kinase activity|myosin kinase activity|myosin-light-chain kinase activity|MLCK|STK18				Reactome:R-HSA-5668978|EC:2.7.11.18|RHEA:22004|MetaCyc:2.7.11.18-RXN|Reactome:R-HSA-445813									molecular_function											owl:Class	
GO:0010339	biolink:NamedThing	external side of cell wall	The side of the cell wall that is opposite to the side that faces the cell and its contents.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0098790	biolink:NamedThing	ncRNA transcription associated with protein coding gene TSS/TES	The transcription of non-coding RNA associated with transcriptional start and end sites of protein coding genes. This occurs at some low level for many protein coding genes.	tmpzr1t_l9r_go_relaxed.owl	pasRNA transcription													biological_process											owl:Class	
GO:0000017	biolink:NamedThing	alpha-glucoside transport	The directed movement of alpha-glucosides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Alpha-glucosides are glycosides in which the sugar group is a glucose residue, and the anomeric carbon of the bond is in an alpha configuration.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0060097	biolink:NamedThing	cytoskeletal rearrangement involved in phagocytosis, engulfment	The assembly, arrangement, or disassembly of cytoskeletal structures that is involved in the internalization of bacteria, immune complexes and other particulate matter or of an apoptotic cell by phagocytosis.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0006911	biolink:NamedThing	phagocytosis, engulfment	The internalization of bacteria, immune complexes and other particulate matter or of an apoptotic cell by phagocytosis, including the membrane and cytoskeletal processes required, which involves one of three mechanisms: zippering of pseudopods around a target via repeated receptor-ligand interactions, sinking of the target directly into plasma membrane of the phagocytosing cell, or induced uptake via an enhanced membrane ruffling of the phagocytosing cell similar to macropinocytosis.	tmpzr1t_l9r_go_relaxed.owl	phagosome formation|phagosome biosynthesis													biological_process											owl:Class	
GO:0030048	biolink:NamedThing	actin filament-based movement	Movement of organelles or other particles along actin filaments, or sliding of actin filaments past each other, mediated by motor proteins.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0006654	biolink:NamedThing	phosphatidic acid biosynthetic process	The chemical reactions and pathways resulting in the formation of phosphatidic acid, any derivative of glycerol phosphate in which both the remaining hydroxyl groups of the glycerol moiety are esterified with fatty acids.	tmpzr1t_l9r_go_relaxed.owl	phosphatidic acid formation|phosphatidic acid biosynthesis|phosphatidic acid anabolism|phosphatidic acid synthesis													biological_process											owl:Class	
GO:1905224	biolink:NamedThing	clathrin-coated pit assembly	The aggregation, arrangement and bonding together of a set of components to form a clathrin-coated pit.	tmpzr1t_l9r_go_relaxed.owl	coated pit assembly|clathrin-coated pit formation|coated pit formation							bf	2016-06-07T11:33:28Z					biological_process											owl:Class	
GO:0016029	biolink:NamedThing	subrhabdomeral cisterna	A membrane-bounded compartment that is found at the base of the rhabdomere and contains stored calcium, InsP3 receptors and smooth endoplasmic reticulum Ca2+-ATPase.	tmpzr1t_l9r_go_relaxed.owl	SMC|submicrovillar cisterna													cellular_component											owl:Class	
GO:0009942	biolink:NamedThing	longitudinal axis specification	The establishment, maintenance and elaboration of the longitudinal axis. In plants, this is the axis that runs from the shoot to the root.	tmpzr1t_l9r_go_relaxed.owl	longitudinal axis determination|apical-basal pattern specification													biological_process											owl:Class	
GO:1902751	biolink:NamedThing	positive regulation of cell cycle G2/M phase transition	Any signalling pathway that activates or increases the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to M phase of the cell cycle.	tmpzr1t_l9r_go_relaxed.owl	up regulation of cell cycle G2/M phase transition|up-regulation of cell cycle G2/M phase transition|upregulation of cell cycle G2/M phase transition|activation of cell cycle G2/M phase transition							jl	2014-03-05T15:38:27Z					biological_process											owl:Class	
GO:0007183	biolink:NamedThing	SMAD protein complex assembly	The aggregation, arrangement and bonding together of a set of components to form a protein complex that contains SMAD proteins.	tmpzr1t_l9r_go_relaxed.owl	SMAD protein heteromerization													biological_process											owl:Class	
GO:0010439	biolink:NamedThing	regulation of glucosinolate biosynthetic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glucosinolates, substituted thioglucosides found in rapeseed products and related cruciferae.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1900260	biolink:NamedThing	negative regulation of RNA-directed 5'-3' RNA polymerase activity	Any process that stops, prevents or reduces the frequency, rate or extent of RNA-directed 5'-3' RNA polymerase activity.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of ribonucleic synthetase activity|down regulation of PB2 proteins|downregulation of polymerase L|inhibition of PB1 proteins|downregulation of PB1 proteins|down-regulation of ribonucleic acid-dependent ribonucleate nucleotidyltransferase activity|inhibition of RNA nucleotidyltransferase (RNA-directed) activity|inhibition of 3D polymerase activity|down regulation of ribonucleic synthetase activity|down-regulation of 3D polymerase activity|down regulation of ribonucleic acid-dependent ribonucleate nucleotidyltransferase activity|negative regulation of RNA nucleotidyltransferase (RNA-directed) activity|down regulation of RNA-dependent RNA replicase activity|negative regulation of ribonucleic acid-dependent ribonucleate nucleotidyltransferase activity|inhibition of RNA synthetase activity|inhibition of nucleoside-triphosphate:RNA nucleotidyltransferase (RNA-directed)|downregulation of Q-beta replicase activity|downregulation of ribonucleic synthetase activity|downregulation of ribonucleic acid replicase activity|inhibition of polymerase L|down-regulation of polymerase L|down-regulation of PB1 proteins|down regulation of ribonucleic acid-dependent ribonucleic acid polymerase activity|down regulation of phage f2 replicase|downregulation of ribonucleic acid-dependent ribonucleic acid polymerase activity|inhibition of ribonucleic acid-dependent ribonucleate nucleotidyltransferase activity|inhibition of RNA-dependent RNA replicase activity|down-regulation of RDRP|inhibition of PB2 proteins|inhibition of RDRP|down-regulation of RNA-dependent ribonucleate nucleotidyltransferase activity|down-regulation of ribonucleic replicase activity|negative regulation of 3D polymerase activity|downregulation of 3D polymerase activity|inhibition of RNA-dependent RNA polymerase activity|negative regulation of polymerase L|down regulation of RNA-dependent RNA polymerase activity|negative regulation of RNA-directed RNA polymerase activity|inhibition of Q-beta replicase activity|down-regulation of ribonucleic acid replicase activity|negative regulation of RNA-dependent ribonucleate nucleotidyltransferase activity|down-regulation of RNA-directed RNA polymerase activity|inhibition of transcriptase|negative regulation of RDRP|down regulation of RNA-directed RNA polymerase activity|downregulation of RNA-dependent RNA replicase activity|down-regulation of nucleoside-triphosphate:RNA nucleotidyltransferase (RNA-directed)|down regulation of nucleoside-triphosphate:RNA nucleotidyltransferase (RNA-directed)|negative regulation of phage f2 replicase|down regulation of RDRP|downregulation of ribonucleic replicase activity|down regulation of polymerase L|down-regulation of RNA-dependent RNA polymerase activity|inhibition of phage f2 replicase|inhibition of ribonucleic synthetase activity|downregulation of RNA synthetase activity|down regulation of PB1 proteins|down regulation of RNA nucleotidyltransferase (RNA-directed) activity|down-regulation of RNA nucleotidyltransferase (RNA-directed) activity|down regulation of RNA replicase activity|downregulation of phage f2 replicase|inhibition of RNA-dependent ribonucleate nucleotidyltransferase activity|negative regulation of ribonucleic replicase activity|down-regulation of RNA synthetase activity|down-regulation of ribonucleic acid-dependent ribonucleic acid polymerase activity|down regulation of RNA-dependent ribonucleate nucleotidyltransferase activity|down-regulation of RNA-dependent RNA replicase activity|downregulation of RNA-dependent RNA polymerase activity|downregulation of RNA-dependent ribonucleate nucleotidyltransferase activity|downregulation of transcriptase|downregulation of nucleoside-triphosphate:RNA nucleotidyltransferase (RNA-directed)|down-regulation of PB2 proteins|down-regulation of transcriptase|downregulation of RDRP|downregulation of PB2 proteins|negative regulation of RNA synthetase activity|downregulation of ribonucleic acid-dependent ribonucleate nucleotidyltransferase activity|inhibition of RNA replicase activity|down-regulation of Q-beta replicase activity|negative regulation of ribonucleic acid-dependent ribonucleic acid polymerase activity|inhibition of RNA-directed RNA polymerase activity|negative regulation of RNA-dependent RNA polymerase activity|negative regulation of PB2 proteins|down regulation of Q-beta replicase activity|inhibition of ribonucleic acid replicase activity|downregulation of RNA replicase activity|negative regulation of Q-beta replicase activity|inhibition of ribonucleic acid-dependent ribonucleic acid polymerase activity|down regulation of ribonucleic replicase activity|negative regulation of transcriptase|down-regulation of RNA replicase activity|negative regulation of RNA-dependent RNA replicase activity|negative regulation of RNA replicase activity|negative regulation of ribonucleic synthetase activity|down regulation of ribonucleic acid replicase activity|downregulation of RNA nucleotidyltransferase (RNA-directed) activity|negative regulation of nucleoside-triphosphate:RNA nucleotidyltransferase (RNA-directed)|down-regulation of phage f2 replicase|down regulation of 3D polymerase activity|downregulation of RNA-directed RNA polymerase activity|down regulation of RNA synthetase activity|inhibition of ribonucleic replicase activity|negative regulation of ribonucleic acid replicase activity|down regulation of transcriptase|negative regulation of PB1 proteins							tb	2012-04-03T11:02:03Z					biological_process											owl:Class	
GO:0006826	biolink:NamedThing	iron ion transport	The directed movement of iron (Fe) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	iron ion import|ferric iron uptake|ferric ion import|iron transport|ferric ion transport|ferrous iron transport|ferrous ion transport|ferric iron transport|ferric iron import							pr	2012-04-18T03:33:45Z			GO:0033216|GO:0015681|GO:0015682|GO:0097286|GO:0015684		biological_process											owl:Class	
GO:0006415	biolink:NamedThing	translational termination	The process resulting in the release of a polypeptide chain from the ribosome, usually in response to a termination codon (UAA, UAG, or UGA in the universal genetic code).	tmpzr1t_l9r_go_relaxed.owl	protein synthesis termination|translational complex disassembly|translation termination											GO:0006456|GO:0006443		biological_process											owl:Class	
GO:0030905	biolink:NamedThing	retromer, tubulation complex	The dimeric subcomplex of the retromer, believed to be peripherally associated with the membrane. This dimeric complex is responsible for remodelling endosomal membranes to form a tube-structure to which cargo molecules are selected for recycling. The budding yeast complex comprises Vps5p and Vps17p, and may contain multiple copies of a Vps5p/Vps17p dimer. The mammalian complex contains SNX1 or SNX2 dimerized with SNX5 or SNX6.	tmpzr1t_l9r_go_relaxed.owl	retromer complex, outer shell|SNX-BAR dimer|heterodimeric membrane-deforming retromer subcomplex													cellular_component											owl:Class	
GO:0021570	biolink:NamedThing	rhombomere 4 development	The process whose specific outcome is the progression of rhombomere 4 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0060978	biolink:NamedThing	angiogenesis involved in coronary vascular morphogenesis	Blood vessel formation in the heart when new vessels emerge from the proliferation of pre-existing blood vessels.	tmpzr1t_l9r_go_relaxed.owl	coronary vasculature angiogenesis|coronary blood vessel angiogenesis|angiogenesis involved in heart vascular morphogenesis|angiogenesis involved in cardiac vascular morphogenesis							dph	2009-10-06T02:02:12Z					biological_process											owl:Class	
GO:0018315	biolink:NamedThing	molybdenum incorporation into molybdenum-molybdopterin complex	The incorporation of molybdenum into a molybdenum-molybdopterin complex.	tmpzr1t_l9r_go_relaxed.owl	molybdenum incorporation into metallo-pterin complex											GO:0042041		biological_process											owl:Class	
GO:0021910	biolink:NamedThing	smoothened signaling pathway involved in ventral spinal cord patterning	The series of molecular signals generated as a consequence of activation of the transmembrane protein Smoothened that results in the spatial identity of regions along the dorsal-ventral axis of the spinal cord.	tmpzr1t_l9r_go_relaxed.owl	hedgehog signaling pathway involved in ventral spinal cord patterning|hh signaling pathway involved in ventral spinal cord patterning|smoothened signalling pathway in ventral spinal cord patterning													biological_process											owl:Class	
GO:1903623	biolink:NamedThing	negative regulation of RNA polymerase III activity	Any process that stops, prevents or reduces the frequency, rate or extent of RNA polymerase III activity.	tmpzr1t_l9r_go_relaxed.owl	downregulation of DNA-directed RNA polymerase activity involved in transcription from RNA polymerase III promoter|down-regulation of DNA-directed RNA polymerase activity involved in transcription from RNA polymerase III promoter|downregulation of RNA polymerase III activity|down-regulation of RNA polymerase III activity|down regulation of DNA-directed RNA polymerase activity involved in transcription from RNA polymerase III promoter|down regulation of RNA polymerase III activity|inhibition of RNA polymerase III activity|negative regulation of DNA-directed RNA polymerase activity involved in transcription from RNA polymerase III promoter|inhibition of DNA-directed RNA polymerase activity involved in transcription from RNA polymerase III promoter							al	2014-11-19T18:24:37Z					biological_process											owl:Class	
GO:0042695	biolink:NamedThing	thelarche	The beginning of development of the breasts in the female.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Thelarche									biological_process											owl:Class	
GO:0098565	biolink:NamedThing	lumenal side of endosome membrane	The side (leaflet) of the endosome membrane that faces the lumen.	tmpzr1t_l9r_go_relaxed.owl	internal leaflet of endosome membrane|internal side of endosome membrane													cellular_component											owl:Class	
GO:0002353	biolink:NamedThing	plasma kallikrein-kinin cascade	A series of reactions that takes place outside the cell occurring in response to tissue damage and initiated within blood plasma by the action of activated Factor XII (Hageman Factor) on prekallikrein to convert it to plasma kallikrein, and the subsequent reaction of plasma kallikrein with high molecular weight kininogen. The ultimate product of the plasma kallikrein-kinin cascade is bradykinin, an agent known to induce smooth muscle contraction, vasoconstriction, and increased vascular permeability.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1900316	biolink:NamedThing	negative regulation of maltopentaose transport	Any process that stops, prevents or reduces the frequency, rate or extent of maltopentaose transport.	tmpzr1t_l9r_go_relaxed.owl	inhibition of maltopentaose transport|down-regulation of maltopentaose transport|downregulation of maltopentaose transport|down regulation of maltopentaose transport							tt	2012-04-05T07:59:56Z					biological_process											owl:Class	
GO:2001101	biolink:NamedThing	maltopentaose transport	The directed movement of a maltopentaoseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl								jl	2011-09-21T02:18:36Z					biological_process											owl:Class	
GO:0003358	biolink:NamedThing	noradrenergic neuron development	The process whose specific outcome is the progression of a noradrenergic neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.	tmpzr1t_l9r_go_relaxed.owl	norepinephrine secreting neuron development							dph	2009-12-03T10:38:37Z					biological_process											owl:Class	
GO:0019046	biolink:NamedThing	release from viral latency	The process by which a virus begins to replicate following a latency replication decision (switch).	tmpzr1t_l9r_go_relaxed.owl												GO:0075717		biological_process											owl:Class	
GO:0019045	biolink:NamedThing	latent virus replication	Any process required for latent viral replication in a cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0061341	biolink:NamedThing	non-canonical Wnt signaling pathway involved in heart development	The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via effectors other than beta-catenin and contributing to the progression of the heart over time.	tmpzr1t_l9r_go_relaxed.owl	non-canonical Wnt-activated signaling pathway involved in heart development|non-canonical Wnt receptor signaling pathway involved in heart development|non-canonical Wnt receptor signalling pathway involved in heart development							dph	2010-09-29T11:27:34Z					biological_process											owl:Class	
GO:0030435	biolink:NamedThing	sporulation resulting in formation of a cellular spore	The process in which a relatively unspecialized cell acquires the specialized features of a cellular spore, a cell form that can be used for dissemination, for survival of adverse conditions because of its heat and dessication resistance, and/or for reproduction.	tmpzr1t_l9r_go_relaxed.owl	spore formation|spore biosynthesis|cellular spore formation by sporulation|spore differentiation				Wikipedia:Sporogenesis	Note that the synonym 'spore differentiation', like the term name and definition, refers to differentiation into a spore rather than any subsequent developmental changes that a spore may undergo.								biological_process											owl:Class	
GO:0060848	biolink:NamedThing	endothelial cell fate determination	A process involved in cell fate commitment of an endothelial cell. Once determination has taken place, a cell becomes committed to differentiate down a particular pathway regardless of its environment.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-08-12T11:11:14Z					biological_process											owl:Class	
GO:0002364	biolink:NamedThing	NK T cell lineage commitment	The process in which a pro-T cell becomes committed to becoming an NK T cell.	tmpzr1t_l9r_go_relaxed.owl	natural killer T lymphocyte lineage commitment|NK T lymphocyte lineage commitment|natural killer T-cell lineage commitment|NK T-cell lineage commitment|NK T-lymphocyte lineage commitment|natural killer T-lymphocyte lineage commitment													biological_process											owl:Class	
GO:0010599	biolink:NamedThing	production of lsiRNA involved in RNA interference	Cleavage of double-stranded RNA to form lsiRNA (long small interfering RNA), a class of siRNAs 30 to 40 nt in length. lsiRNAs are induced by pathogen infection or under specific growth conditions.	tmpzr1t_l9r_go_relaxed.owl	RNA interference, production of lsiRNA													biological_process											owl:Class	
GO:0003144	biolink:NamedThing	embryonic heart tube formation	The process that gives rise to the embryonic heart tube. This process pertains to the initial formation of a structure from unspecified parts. The embryonic heart tube is an epithelial tube that will give rise to the mature heart.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-09-22T04:22:34Z					biological_process											owl:Class	
GO:0072247	biolink:NamedThing	metanephric glomerular parietal epithelial cell fate commitment	The process in which the developmental fate of a cell becomes restricted such that it will develop into a metanephric glomerular parietal epithelial cell. Metanephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. These cells may also give rise to podocytes.	tmpzr1t_l9r_go_relaxed.owl	metanephric Bowman's capsule cell fate commitment							mah	2010-03-19T03:42:27Z					biological_process											owl:Class	
GO:0004511	biolink:NamedThing	tyrosine 3-monooxygenase activity	Catalysis of the reaction: L-tyrosine + tetrahydrobiopterin + O2 = 3,4-dihydroxy-L-phenylalanine + 4-alpha-hydroxytetrahydrobiopterin + H2O.	tmpzr1t_l9r_go_relaxed.owl	L-tyrosine hydroxylase activity|L-tyrosine,tetrahydrobiopterin:oxygen oxidoreductase (3-hydroxylating)|tyrosine 3-hydroxylase activity|tyrosine hydroxylase activity				EC:1.14.16.2|MetaCyc:TYROSINE-3-MONOOXYGENASE-RXN|RHEA:18201|Reactome:R-HSA-209823									molecular_function											owl:Class	
GO:0031204	biolink:NamedThing	posttranslational protein targeting to membrane, translocation	The process in which a protein translocates through the ER membrane posttranslationally.	tmpzr1t_l9r_go_relaxed.owl	posttranslational protein membrane targeting, translocation|protein translocation during posttranslational protein targeting to membrane													biological_process											owl:Class	
GO:0006620	biolink:NamedThing	posttranslational protein targeting to endoplasmic reticulum membrane	The targeting of proteins to a membrane that occurs after their translation. Some secretory proteins exhibit posttranslational transport into the endoplasmic reticulum (ER) lumen: they are synthesized in their entirety on free cytosolic ribosomes and then released into the cytosol, where they are bound by chaperones which keep them in an unfolded state, and subsequently are translocated across the ER membrane.	tmpzr1t_l9r_go_relaxed.owl	posttranslational endoplasmic reticulum protein-membrane targeting|posttranslational protein endoplasmic reticulum membrane targeting|SRP-independent endoplasmic reticulum protein-membrane targeting|posttranslational protein targeting to ER membrane|posttranslational endoplasmic reticulum membrane targeting													biological_process											owl:Class	
GO:0004105	biolink:NamedThing	choline-phosphate cytidylyltransferase activity	Catalysis of the reaction: CTP + choline phosphate = diphosphate + CDP-choline.	tmpzr1t_l9r_go_relaxed.owl	CTP:phosphorylcholine cytidylyltransferase activity|CTP-phosphocholine cytidylyltransferase activity|phosphorylcholine cytidylyltransferase activity|phosphocholine cytidylyltransferase activity|phosphorylcholine:CTP cytidylyltransferase activity|choline phosphate cytidylyltransferase activity|CTP:phosphocholine cytidylyltransferase activity|CDP-choline synthetase activity|phosphorylcholine transferase activity|CTP:choline-phosphate cytidylyltransferase activity|CDP-choline pyrophosphorylase activity|cytidine diphosphocholine pyrophosphorylase activity				RHEA:18997|EC:2.7.7.15|MetaCyc:2.7.7.15-RXN|Reactome:R-HSA-1483081									molecular_function											owl:Class	
GO:0044722	biolink:NamedThing	renal phosphate excretion	The elimination by an organism of phosphate ions in the urine.	tmpzr1t_l9r_go_relaxed.owl	renal phosphate ion excretion							jl	2012-10-18T14:54:00Z					biological_process											owl:Class	
GO:0033138	biolink:NamedThing	positive regulation of peptidyl-serine phosphorylation	Any process that activates or increases the frequency, rate or extent of the phosphorylation of peptidyl-serine.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0030041	biolink:NamedThing	actin filament polymerization	Assembly of actin filaments by the addition of actin monomers to a filament.	tmpzr1t_l9r_go_relaxed.owl	actin polymerization|actin polymerizing activity													biological_process											owl:Class	
GO:0048496	biolink:NamedThing	maintenance of animal organ identity	The process in which the identity of an animal organ is maintained. Identity is considered to be the aggregate of characteristics by which a structure is recognized.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0060984	biolink:NamedThing	epicardium-derived cardiac vascular smooth muscle cell development	The process whose specific outcome is the progression of a cardiac vascular smooth muscle cell that was derived from the epicardium over time, from its formation to the mature state.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-10-06T03:07:09Z					biological_process											owl:Class	
GO:0097364	biolink:NamedThing	stretch-activated, cation-selective, calcium channel activity involved in regulation of action potential	Enables the transmembrane transfer of a calcium ion by a channel that opens in response to a mechanical stress in the form of stretching, and contributing to the regulation of action potential.	tmpzr1t_l9r_go_relaxed.owl								pr	2012-07-25T04:08:33Z					molecular_function											owl:Class	
GO:0033254	biolink:NamedThing	vacuolar transporter chaperone complex	A protein complex that contains four related proteins that have been implicated in several membrane-related processes, such as sorting of H+-translocating ATPases, endocytosis, ER-Golgi trafficking, vacuole fusion, vacuolar polyphosphate homeostasis and the microautophagic scission of vesicles into the vacuolar lumen. The complex is enriched at the vacuolar membrane, but also found in other cellular compartments, including the ER and the cell periphery. In Saccharomyces, the subunits are Vtc1p, Vtc2p, Vtc3p and Vtc4p.	tmpzr1t_l9r_go_relaxed.owl	VTC complex													cellular_component											owl:Class	
GO:0044612	biolink:NamedThing	nuclear pore linkers	A substructure of the nuclear pore complex (NPC) that serves to connect members of the central transport channel (composed of FG-nucleoporins) to the core scaffold (composed of the inner and outer NPC rings). In S. cerevisiae, the linkers are Nic96p and Nup82p. In vertebrates, they are Nup93 and Nup88. Components are arranged in 8-fold symmetrical 'spokes' around the central transport channel. Both linkers can be isolated in association with specific FG-nucleoporins, complexes that are sometimes referred to as the Nic96 complex (Nic96p-Nsp1p-Nup49p-Nup57p) and the Nup82 complex (Nup82p-Nup116p-Nup159p-Gle2p).	tmpzr1t_l9r_go_relaxed.owl	Nic96 complex|Nup82 complex							jl	2012-06-20T01:22:40Z					cellular_component											owl:Class	
GO:0035710	biolink:NamedThing	CD4-positive, alpha-beta T cell activation	The change in morphology and behavior of a CD4-positive, alpha-beta T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-03-02T03:04:11Z					biological_process											owl:Class	
GO:2000951	biolink:NamedThing	regulation of xyloglucan catabolic process	Any process that modulates the frequency, rate or extent of xyloglucan catabolic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of xyloglucan catabolism							tt	2011-08-01T02:20:16Z					biological_process											owl:Class	
GO:0080143	biolink:NamedThing	regulation of amino acid export	Any process that modulates the frequency, rate or extent of amino acid export. Amino acid export is the directed movement of amino acids out of a cell or organelle.	tmpzr1t_l9r_go_relaxed.owl								dhl	2010-01-20T04:43:56Z					biological_process											owl:Class	
GO:0016483	biolink:NamedThing	tryptophan hydroxylase activator activity	Increases the activity of the enzyme tryptophase hydroxylase.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0004510	biolink:NamedThing	tryptophan 5-monooxygenase activity	Catalysis of the reaction: L-tryptophan + tetrahydrobiopterin + O2 = 5-hydroxy-L-tryptophan + 4-alpha-hydroxytetrahydrobiopterin + H2O.	tmpzr1t_l9r_go_relaxed.owl	indoleacetic acid-5-hydroxylase activity|L-tryptophan,tetrahydrobiopterin:oxygen oxidoreductase (5-hydroxylating)|L-tryptophan hydroxylase activity|tryptophan hydroxylase activity|tryptophan 5-hydroxylase activity				EC:1.14.16.4|RHEA:16709|MetaCyc:TRYPTOPHAN-5-MONOOXYGENASE-RXN|Reactome:R-HSA-209828									molecular_function											owl:Class	
GO:0099058	biolink:NamedThing	integral component of postsynaptic endocytic zone membrane	The component of the postsynaptic endocytic zone membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0034357	biolink:NamedThing	photosynthetic membrane	A membrane enriched in complexes formed of reaction centers, accessory pigments and electron carriers, in which photosynthetic reactions take place.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:1990813	biolink:NamedThing	meiotic centromeric cohesion protection	The process in which the association between sister chromatids of a replicated chromosome centromeric region is maintained during homologous chromosome segregation after cohesin is cleaved by separase along the arm regions.	tmpzr1t_l9r_go_relaxed.owl	protection of centromeric cohesion during meiotic anaphase I							vw	2015-07-28T16:15:31Z					biological_process											owl:Class	
GO:0061042	biolink:NamedThing	vascular wound healing	Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels and contribute to the series of events that restore integrity to damaged vasculature.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-02-25T10:18:26Z					biological_process											owl:Class	
GO:0035321	biolink:NamedThing	maintenance of imaginal disc-derived wing hair orientation	Ensuring that hairs in the imaginal disc-derived wing continue to point distally during development, following the initial establishment of wing hair polarity.	tmpzr1t_l9r_go_relaxed.owl	maintenance of wing hair orientation													biological_process											owl:Class	
GO:0035317	biolink:NamedThing	imaginal disc-derived wing hair organization	A process that is carried out at the cellular level that results in the assembly, arrangement of constituent parts, or disassembly of an imaginal disc-derived wing hair. A wing hair is an actin-rich, polarized, non-sensory apical projection that protrudes from each of the approximately 30,000 wing epithelial cells. An example of this is found in Drosophila melanogaster.	tmpzr1t_l9r_go_relaxed.owl	wing hair organization and biogenesis|wing trichome organization and biogenesis|imaginal disc-derived wing hair organization and biogenesis|wing hair organisation					See also the fly_anatomy.ontology term 'wing hair ; FBbt:00004340'.								biological_process											owl:Class	
GO:1900488	biolink:NamedThing	negative regulation of [2Fe-2S] cluster assembly	Any process that stops, prevents or reduces the frequency, rate or extent of [2Fe-2S] cluster assembly.	tmpzr1t_l9r_go_relaxed.owl	downregulation of 2Fe-2S cluster assembly|down-regulation of [2Fe-2S] cluster assembly|inhibition of [2Fe-2S] cluster biosynthetic process|down-regulation of 2Fe-2S cluster assembly|down regulation of [2Fe-2S] cluster biosynthetic process|down-regulation of [2Fe-2S] cluster biosynthetic process|down regulation of [2Fe-2S] cluster assembly|negative regulation of 2Fe-2S cluster assembly|downregulation of [2Fe-2S] cluster assembly|inhibition of 2Fe-2S cluster assembly|down regulation of 2Fe-2S cluster assembly|negative regulation of [2Fe-2S] cluster biosynthetic process|inhibition of [2Fe-2S] cluster assembly|downregulation of [2Fe-2S] cluster biosynthetic process							tt	2012-05-02T01:22:32Z					biological_process											owl:Class	
GO:0001306	biolink:NamedThing	age-dependent response to oxidative stress	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, where the change varies according to the age of the cell or organism.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0007571	biolink:NamedThing	age-dependent general metabolic decline	A developmental process that arises as the cell progresses toward the end of its lifespan and cause changes cellular metabolism, resulting in a decline in cell function; for example, one aspect of general metabolic decline is a decrease in the efficiency of protein synthesis.	tmpzr1t_l9r_go_relaxed.owl	nucleolar size increase|age-dependent increased protein content|age-dependent decreased translational activity|age-dependent yeast cell size increase													biological_process											owl:Class	
GO:0061700	biolink:NamedThing	GATOR2 complex	A multiprotein subcomplex of the GATOR complex that regulates TORC1 signaling by interacting with the Rag GTPase. In human, this complex consists of WDR24, WDR59, MIOS, SEH1L, and SEC13. In S. cerevisiae, this complex is referred to as SEACAT and contains the Sea2p, Sea3p, Sea4p, Seh1p, Sec13p proteins.	tmpzr1t_l9r_go_relaxed.owl	SEACAT complex					The Rag GTPase complex corresponds to Gtr1-Gtr2 GTPase complex ;  GO:1990131.		dph	2015-05-07T11:13:27Z					cellular_component											owl:Class	
GO:0035859	biolink:NamedThing	Seh1-associated complex	A GTPase-activating protein (GAP) complex that regulates TORC1 signaling by interacting with the Rag GTPase. In S. cerevisiae the complex contains Seh1p, Sec13p, Npr2p, Npr3p, Iml1p, Mtc5p, Rtc1p, and Sea4p.	tmpzr1t_l9r_go_relaxed.owl	GATOR complex|SEA complex	https://github.com/geneontology/go-ontology/issues/21778				The Rag GTPase complex corresponds to Gtr1-Gtr2 GTPase complex ;  GO:1990131.		bf	2011-05-17T10:59:50Z					cellular_component											owl:Class	
GO:0072672	biolink:NamedThing	neutrophil extravasation	The migration of a neutrophil from the blood vessels into the surrounding tissue.	tmpzr1t_l9r_go_relaxed.owl								mah	2011-02-21T03:03:52Z					biological_process											owl:Class	
GO:0072639	biolink:NamedThing	interleukin-33 production	The appearance of interleukin-33 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	tmpzr1t_l9r_go_relaxed.owl	IL33 production|IL-33 production|C9orf26 production|IL1F11 production|interleukin-33 secretion|NF-HEV production|interleukin-33 biosynthetic process											GO:0150126|GO:0072640		biological_process											owl:Class	
GO:1990061	biolink:NamedThing	bacterial degradosome	The degradosome is a protein complex playing a key role in mRNA degradation and RNA processing. It includes a RNA helicase, a 3'-5' phosphate-dependent PNPase and a RNase E bound-enolase.	tmpzr1t_l9r_go_relaxed.owl								bhm	2013-03-20T13:51:49Z					cellular_component											owl:Class	
GO:0072664	biolink:NamedThing	maintenance of protein location in peroxisome	Any process in which a protein is maintained in a specific location in a peroxisome, and is prevented from moving elsewhere.	tmpzr1t_l9r_go_relaxed.owl								mah	2011-02-14T02:51:51Z					biological_process											owl:Class	
GO:0048237	biolink:NamedThing	rough endoplasmic reticulum lumen	The volume enclosed by the membranes of the rough endoplasmic reticulum.	tmpzr1t_l9r_go_relaxed.owl	rough ER lumen|RER lumen				NIF_Subcellular:sao1819509473									cellular_component											owl:Class	
GO:0005791	biolink:NamedThing	rough endoplasmic reticulum	The rough (or granular) endoplasmic reticulum (ER) has ribosomes adhering to the outer surface; the ribosomes are the site of translation of the mRNA for those proteins which are either to be retained within the cisternae (ER-resident proteins), the proteins of the lysosomes, or the proteins destined for export from the cell. Glycoproteins undergo their initial glycosylation within the cisternae.	tmpzr1t_l9r_go_relaxed.owl	RER|rough ER				Wikipedia:Endoplasmic_reticulum#Rough_endoplasmic_reticulum|NIF_Subcellular:sao1881364067									cellular_component											owl:Class	
GO:0001699	biolink:NamedThing	acetylcholine-induced gastric acid secretion	The regulated release of gastric acid by parietal cells in response to acetylcholine.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1905145	biolink:NamedThing	cellular response to acetylcholine	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acetylcholine stimulus.	tmpzr1t_l9r_go_relaxed.owl								dos	2016-04-14T08:54:58Z					biological_process											owl:Class	
GO:0008091	biolink:NamedThing	spectrin	Membrane associated dimeric protein (240 and 220 kDa) of erythrocytes. Forms a complex with ankyrin, actin and probably other components of the membrane cytoskeleton, so that there is a mesh of proteins underlying the plasma membrane, potentially restricting the lateral mobility of integral proteins.	tmpzr1t_l9r_go_relaxed.owl					NIF_Subcellular:sao536287099|Wikipedia:Spectrin									cellular_component											owl:Class	
GO:0030864	biolink:NamedThing	cortical actin cytoskeleton	The portion of the actin cytoskeleton, comprising filamentous actin and associated proteins, that lies just beneath the plasma membrane.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0110033	biolink:NamedThing	regulation of adenylate cyclase-activating glucose-activated G protein-coupled receptor signaling pathway	Any process that modulates the frequency, rate or extent of the adenylate cyclase-activating glucose-activated G protein-coupled receptor signaling pathway, the series of molecular signals generated as a consequence of glucose binding to a G protein-coupled receptor, where the pathway proceeds with activation of adenylyl cyclase and a subsequent increase in the concentration of cyclic AMP (cAMP).	tmpzr1t_l9r_go_relaxed.owl	regulation of adenylate cyclase-activating glucose-activated G-protein coupled receptor signaling pathway							kmv	2017-07-17T20:22:20Z					biological_process											owl:Class	
GO:0010619	biolink:NamedThing	adenylate cyclase-activating glucose-activated G protein-coupled receptor signaling pathway	The series of molecular signals generated as a consequence of glucose binding to a G protein-coupled receptor, where the pathway proceeds with activation of adenylyl cyclase and a subsequent increase in the concentration of cyclic AMP (cAMP).	tmpzr1t_l9r_go_relaxed.owl	glucose-sensing PKA pathway|activation of adenylate cyclase activity by glucose involved in G-protein signaling|activation of adenylate cyclase activity by glucose-triggered G-protein signalling pathway|activation of adenylate cyclase activity by glucose-triggered G-protein signaling pathway													biological_process											owl:Class	
GO:0043584	biolink:NamedThing	nose development	The process whose specific outcome is the progression of the nose over time, from its formation to the mature structure. The nose is the specialized structure of the face that serves as the organ of the sense of smell and as part of the respiratory system. Includes the nasi externus (external nose) and cavitas nasi (nasal cavity).	tmpzr1t_l9r_go_relaxed.owl	nasus development													biological_process											owl:Class	
GO:0002393	biolink:NamedThing	lysosomal enzyme production involved in inflammatory response	The synthesis or release of lysosomal enzymes following a stimulus as part of a inflammatory response, resulting in an increase in intracellular or extracellular levels.	tmpzr1t_l9r_go_relaxed.owl	production of lysosomal enzymes involved in inflammatory response|lysosomal enzyme production involved in acute inflammatory response|production of lysosomal enzymes involved in acute inflammatory response													biological_process											owl:Class	
GO:0005870	biolink:NamedThing	actin capping protein of dynactin complex	A heterodimer consisting of alpha and beta subunits that binds to and caps the barbed ends of actin filaments, nucleates the polymerization of actin monomers but does not sever actin filaments, and which is a part of the dynactin complex.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0005869	biolink:NamedThing	dynactin complex	A 20S multiprotein assembly of total mass about 1.2 MDa that activates dynein-based activity in vivo. A large structural component of the complex is an actin-like 40 nm filament composed of actin-related protein, to which other components attach.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0090038	biolink:NamedThing	negative regulation of protein kinase C signaling	Any process that decreases the frequency, rate, or extent of a series of reactions, mediated by the intracellular serine/threonine kinase protein kinase C, which occurs as a result of a single trigger reaction or compound.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of protein kinase C signaling cascade|negative regulation of protein kinase C signalling cascade							tb	2009-08-03T11:29:33Z					biological_process											owl:Class	
GO:0070528	biolink:NamedThing	protein kinase C signaling	A series of reactions, mediated by the intracellular serine/threonine kinase protein kinase C, which occurs as a result of a single trigger reaction or compound.	tmpzr1t_l9r_go_relaxed.owl	PKC signal transduction|protein kinase C signalling cascade|protein kinase C signal transduction|PKC signaling cascade|protein kinase C signaling cascade													biological_process											owl:Class	
GO:0060040	biolink:NamedThing	retinal bipolar neuron differentiation	The process in which a relatively unspecialized cell acquires specialized features of a bipolar cell, the last neuron to be generated in the retina.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1900854	biolink:NamedThing	positive regulation of terrequinone A biosynthetic process	Any process that activates or increases the frequency, rate or extent of terrequinone A biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	upregulation of terrequinone A biosynthetic process|up regulation of terrequinone A biosynthetic process|up-regulation of terrequinone A biosynthetic process							di	2012-06-07T09:47:38Z					biological_process											owl:Class	
GO:0097401	biolink:NamedThing	synaptic vesicle lumen acidification	The acidification of the synaptic vesicle lumen via transport of protons into the vesicle. The resulting electrochemical gradient powers neurotransmitter loading.	tmpzr1t_l9r_go_relaxed.owl	synaptic vesicle proton loading|synaptic vesicle lumen pH reduction							pr	2012-10-25T09:03:34Z					biological_process											owl:Class	
GO:0019801	biolink:NamedThing	cyclization of asparagine involved in intein-mediated protein splicing	The cyclization of asparagine to yield an L-aspartimide (otherwise known as alpha-aminosuccinimide) residue at the C-terminus of an excised intein during protein splicing.	tmpzr1t_l9r_go_relaxed.owl	cyclization of asparagine, during protein splicing				RESID:AA0302	See also the biological process term 'intein-mediated protein splicing ; GO:0016539'.								biological_process											owl:Class	
GO:0016539	biolink:NamedThing	intein-mediated protein splicing	The removal of an internal amino acid sequence (an intein) from a protein during protein maturation; the excision of inteins is precise and the N- and C-terminal exteins are joined by a normal peptide bond. Protein splicing involves 4 nucleophilic displacements by the 3 conserved splice junction residues.	tmpzr1t_l9r_go_relaxed.owl	intein													biological_process											owl:Class	
GO:0005319	biolink:NamedThing	lipid transporter activity	Enables the directed movement of lipids into, out of or within a cell, or between cells.	tmpzr1t_l9r_go_relaxed.owl	lipophorin|apolipoprotein				Reactome:R-HSA-8866329|Reactome:R-HSA-1369028|Reactome:R-HSA-5683672|Reactome:R-HSA-5688397|Reactome:R-HSA-1369052|Reactome:R-HSA-5682285|Reactome:R-HSA-5683714|Reactome:R-HSA-174786|Reactome:R-HSA-6801250|Reactome:R-HSA-8848053|Reactome:R-HSA-5682311									molecular_function											owl:Class	
GO:2000478	biolink:NamedThing	positive regulation of metanephric glomerular visceral epithelial cell development	Any process that activates or increases the frequency, rate or extent of metanephric glomerular visceral epithelial cell development.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of metanephric podocyte development							yaf	2011-03-09T05:17:26Z					biological_process											owl:Class	
GO:0008237	biolink:NamedThing	metallopeptidase activity	Catalysis of the hydrolysis of peptide bonds by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.	tmpzr1t_l9r_go_relaxed.owl	metalloprotease activity|metalloproteinase activity				Reactome:R-HSA-5211356|Reactome:R-HSA-2666278|Reactome:R-HSA-5211391|Reactome:R-HSA-157632|Reactome:R-HSA-2022399|Reactome:R-HSA-5211400|Reactome:R-HSA-2022393|Reactome:R-HSA-193679|Reactome:R-HSA-5211387|Reactome:R-HSA-157629|Reactome:R-HSA-2730752|Reactome:R-HSA-2220976|Reactome:R-HSA-5211405|Reactome:R-HSA-5211340|Reactome:R-HSA-9013284|Reactome:R-HSA-9604264|Reactome:R-HSA-2220944|Reactome:R-HSA-2022368|Reactome:R-HSA-9662837|Reactome:R-HSA-3928660|Reactome:R-HSA-8986181|Reactome:R-HSA-2022396									molecular_function											owl:Class	
GO:0061034	biolink:NamedThing	olfactory bulb mitral cell layer development	The progression of the olfactory bulb mitral cell layer over time from its initial formation until its mature state. The mitral cell layer is composed of pyramidal neurons whose cell bodies are located between the granule cell layer and the plexiform layer.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-02-09T03:30:23Z					biological_process											owl:Class	
GO:0021772	biolink:NamedThing	olfactory bulb development	The progression of the olfactory bulb over time from its initial formation until its mature state. The olfactory bulb coordinates neuronal signaling involved in the perception of smell. It receives input from the sensory neurons and outputs to the olfactory cortex.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0099577	biolink:NamedThing	regulation of translation at presynapse, modulating synaptic transmission	Any process that modulates synaptic transmission by regulating translation occurring at the presynapse.	tmpzr1t_l9r_go_relaxed.owl						Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.								biological_process											owl:Class	
GO:0030430	biolink:NamedThing	host cell cytoplasm	The cytoplasm of a host cell.	tmpzr1t_l9r_go_relaxed.owl	other organism cytoplasm							pr	2014-12-01T14:14:21Z			GO:0097679		cellular_component											owl:Class	
GO:1902499	biolink:NamedThing	positive regulation of protein autoubiquitination	Any process that activates or increases the frequency, rate or extent of protein autoubiquitination.	tmpzr1t_l9r_go_relaxed.owl	upregulation of protein self-ubiquitinylation|activation of protein autoubiquitination|upregulation of protein autoubiquitination|upregulation of protein auto-ubiquitinylation|up-regulation of protein self-ubiquitination|up-regulation of protein self-ubiquitinylation|upregulation of protein auto-ubiquitination|up regulation of protein self-ubiquitination|up-regulation of protein autoubiquitination|up-regulation of protein auto-ubiquitination|activation of protein self-ubiquitinylation|up regulation of protein autoubiquitinylation|up regulation of protein auto-ubiquitinylation|upregulation of protein autoubiquitinylation|upregulation of protein self-ubiquitination|positive regulation of protein auto-ubiquitination|up-regulation of protein autoubiquitinylation|activation of protein autoubiquitinylation|positive regulation of protein self-ubiquitination|up-regulation of protein auto-ubiquitinylation|positive regulation of protein auto-ubiquitinylation|positive regulation of protein self-ubiquitinylation|up regulation of protein self-ubiquitinylation|activation of protein auto-ubiquitinylation|activation of protein auto-ubiquitination|positive regulation of protein autoubiquitinylation|up regulation of protein autoubiquitination|up regulation of protein auto-ubiquitination|activation of protein self-ubiquitination							rb	2013-11-13T21:03:37Z					biological_process											owl:Class	
GO:0060051	biolink:NamedThing	negative regulation of protein glycosylation	Any process that stops, prevents, or reduces the frequency, rate or extent of the glycosylation of one or more amino acid residues within a protein. Protein glycosylation is the addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid, e.g. the addition of glycan chains to proteins.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of protein amino acid glycosylation													biological_process											owl:Class	
GO:0061825	biolink:NamedThing	podosome core	The F-actin-rich core of an adhesion structure characterized by formation upon cell substrate contact and localization at the substrate-attached part of the cell.	tmpzr1t_l9r_go_relaxed.owl								dph	2017-01-14T14:42:45Z					cellular_component											owl:Class	
GO:0002102	biolink:NamedThing	podosome	An actin-rich adhesion structure characterized by formation upon cell substrate contact and localization at the substrate-attached part of the cell, contain an F-actin-rich core surrounded by a ring structure containing proteins such as vinculin and talin, and have a diameter of 0.5 mm.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Podosome	Note that podosomes can be distinguished from other F-actin-rich structures or from other matrix contacts. For example, focal adhesions and focal contacts do not display a core structure of F-actin. Unlike focal adhesions, podosome assembly does not require de novo protein synthesis. However, most of the podosome ring components are found in focal adhesions and other cell-matrix contacts. Podosomes are typically found in cells that cross tissue boundaries, recruited to the leading edge of migrating cells, and are often sites of extracellular matrix degradation.								cellular_component											owl:Class	
GO:0007147	biolink:NamedThing	female meiosis II	The cell cycle process in which the second meiotic division occurs in the female germline.	tmpzr1t_l9r_go_relaxed.owl	female meiosis II nuclear division													biological_process											owl:Class	
GO:0032046	biolink:NamedThing	micropexophagy-specific membrane apparatus	A membrane-bounded flattened sac that is formed during micropexophagy between the membrane tips of an engulfing vacuole, completing the engulfment and sequestration of peroxisomes from the cytosol, and forming a micropexophagic body within the lumen of the vacuole.	tmpzr1t_l9r_go_relaxed.owl	MIPA|micropexophagic apparatus													cellular_component											owl:Class	
GO:1902429	biolink:NamedThing	positive regulation of water channel activity	Any process that activates or increases the frequency, rate or extent of water channel activity.	tmpzr1t_l9r_go_relaxed.owl	activation of water channel activity|up regulation of water channel activity|activation of aquaporin|up-regulation of aquaporin|aquaporin activation|up regulation of aquaporin|up-regulation of water channel activity|upregulation of aquaporin|upregulation of water channel activity|positive regulation of aquaporin							bf	2013-09-23T12:56:49Z					biological_process											owl:Class	
GO:0002468	biolink:NamedThing	dendritic cell antigen processing and presentation	The process in which a dendritic cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1904529	biolink:NamedThing	regulation of actin filament binding	Any process that modulates the frequency, rate or extent of actin filament binding.	tmpzr1t_l9r_go_relaxed.owl	regulation of actin cross-linking activity|regulation of F-actin binding							als	2015-07-30T10:41:49Z					biological_process											owl:Class	
GO:0051015	biolink:NamedThing	actin filament binding	Binding to an actin filament, also known as F-actin, a helical filamentous polymer of globular G-actin subunits.	tmpzr1t_l9r_go_relaxed.owl	actin cross-linking activity|F-actin binding													molecular_function											owl:Class	
GO:0020032	biolink:NamedThing	basal ring of apical complex	An electron dense ring at the most posterior position of the apical complex, from which the subpellicular microtubules originate; formed during an invasive life cycle stage of an apicomplexan parasite.	tmpzr1t_l9r_go_relaxed.owl	posterior polar ring of apical complex|preconoidal ring of apical complex|lower polar ring of apical complex													cellular_component											owl:Class	
GO:0098774	biolink:NamedThing	curli	A proteinaceous extracellular fiber, produced by an enteric bacterium, that is involved in surface and cell-cell contacts that promote community behavior and host colonization.	tmpzr1t_l9r_go_relaxed.owl	thin aggregative fimbrae|tafi													cellular_component											owl:Class	
GO:2000055	biolink:NamedThing	positive regulation of Wnt signaling pathway involved in dorsal/ventral axis specification	Any process that activates or increases the frequency, rate or extent of Wnt signaling pathway involved in dorsal/ventral axis specification.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of Wnt-activated signaling pathway involved in dorsal/ventral axis specification|positive regulation of Wnt receptor signaling pathway involved in dorsal/ventral axis specification|positive regulation of Wnt receptor signalling pathway involved in dorsal/ventral axis specification							jl	2010-08-20T01:13:40Z					biological_process											owl:Class	
GO:0044332	biolink:NamedThing	Wnt signaling pathway involved in dorsal/ventral axis specification	The series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of the target cell contributing to the establishment, maintenance and elaboration of the dorsal/ventral axis.	tmpzr1t_l9r_go_relaxed.owl	Wnt receptor signalling pathway involved in dorsal/ventral axis specification|Wnt receptor signaling pathway involved in dorsal/ventral axis specification|Wnt-activated signaling pathway involved in dorsal/ventral axis specification							jl	2010-08-20T11:30:30Z					biological_process											owl:Class	
GO:1903398	biolink:NamedThing	regulation of m7G(5')pppN diphosphatase activity	Any process that modulates the frequency, rate or extent of m7G(5')pppN diphosphatase activity.	tmpzr1t_l9r_go_relaxed.owl	regulation of 7-methylguanosine-5'-triphospho-5'-polynucleotide 7-methylguanosine-5'-phosphohydrolase activity|regulation of decapase activity|regulation of m7G(5')pppN pyrophosphatase activity|regulation of M(7)G(5')pppN pyrophosphatase activity							mah	2014-09-01T10:16:40Z					biological_process											owl:Class	
GO:2000884	biolink:NamedThing	glucomannan catabolic process	The chemical reactions and pathways resulting in the breakdown of a glucomannan.	tmpzr1t_l9r_go_relaxed.owl	glucomannan catabolism							jl	2011-07-28T09:19:03Z					biological_process											owl:Class	
GO:0075009	biolink:NamedThing	germ tube formation	Development of slender tubular outgrowth first produced by most symbiont spores immediately following germination on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	germ tube formation on or near host													biological_process											owl:Class	
GO:0045632	biolink:NamedThing	negative regulation of mechanoreceptor differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of mechanoreceptor differentiation.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of mechanoreceptor differentiation|inhibition of mechanoreceptor differentiation|down regulation of mechanoreceptor differentiation|downregulation of mechanoreceptor differentiation													biological_process											owl:Class	
GO:0042490	biolink:NamedThing	mechanoreceptor differentiation	The process in which a relatively unspecialized cell acquires specialized features of a mechanoreceptor, a cell specialized to transduce mechanical stimuli and relay that information centrally in the nervous system.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0001824	biolink:NamedThing	blastocyst development	The process whose specific outcome is the progression of the blastocyst over time, from its formation to the mature structure. The mammalian blastocyst is a hollow ball of cells containing two cell types, the inner cell mass and the trophectoderm.	tmpzr1t_l9r_go_relaxed.owl						See also the Anatomical Dictionary for Mouse Development ontology terms 'TS5, embryo ; EMAP:23', 'TS5, inner cell mass ; EMAP:24' and 'TS5, trophectoderm; EMAP:28'.								biological_process											owl:Class	
GO:0031672	biolink:NamedThing	A band	The dark-staining region of a sarcomere, in which myosin thick filaments are present; the center is traversed by the paler H zone, which in turn contains the M line.	tmpzr1t_l9r_go_relaxed.owl	anisotropic disc|A disc|transverse disc|Q disc				Wikipedia:Sarcomere#bands									cellular_component											owl:Class	
GO:0000918	biolink:NamedThing	division septum site selection	The process of marking the site where a division septum will form.	tmpzr1t_l9r_go_relaxed.owl	septin assembly and septum formation|septin assembly and septum biosynthesis|selection of site for barrier cell septum biosynthesis|selection of site for division septum formation|selection of site for barrier cell septum formation|septum positioning													biological_process											owl:Class	
GO:0035783	biolink:NamedThing	CD4-positive, alpha-beta T cell costimulation	The process of providing, via surface-bound receptor-ligand pairs, a second, antigen-independent, signal in addition to that provided by the T cell receptor to augment CD4-positive, alpha-beta T cell activation.	tmpzr1t_l9r_go_relaxed.owl	CD4-positive, alpha beta T cell costimulation							bf	2011-04-04T11:28:52Z					biological_process											owl:Class	
GO:0048457	biolink:NamedThing	floral whorl morphogenesis	The process in which the anatomical structures of the floral whorl are generated and organized.	tmpzr1t_l9r_go_relaxed.owl												GO:0048414		biological_process											owl:Class	
GO:0004953	biolink:NamedThing	icosanoid receptor activity	Combining with an icosanoid to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	eicosanoid receptor activity													molecular_function											owl:Class	
GO:0050542	biolink:NamedThing	icosanoid binding	Binding to icosanoids, any C20 polyunsaturated fatty acids or their derivatives, including the leukotrienes and the prostanoids.	tmpzr1t_l9r_go_relaxed.owl	eicosanoid binding													molecular_function											owl:Class	
GO:1902288	biolink:NamedThing	regulation of defense response to oomycetes	Any process that modulates the frequency, rate or extent of defense response to oomycetes.	tmpzr1t_l9r_go_relaxed.owl								ms	2013-07-09T13:45:32Z					biological_process											owl:Class	
GO:0002229	biolink:NamedThing	defense response to oomycetes	Reactions triggered in response to the presence of oomycetes that act to protect the cell or organism.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0035193	biolink:NamedThing	larval central nervous system remodeling	Reorganization of the pre-existing, functional larval central nervous system into one that can serve the novel behavioral needs of the adult. An example of this process is found in Drosophila melanogaster.	tmpzr1t_l9r_go_relaxed.owl	CNS metamorphosis|central nervous system metamorphosis													biological_process											owl:Class	
GO:0002165	biolink:NamedThing	instar larval or pupal development	The process whose specific outcome is the progression of the instar larva or pupa over time, from its formation to the mature structure. An example of this process is found in Drosophila melanogaster.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0007470	biolink:NamedThing	prothoracic disc morphogenesis	The process in which the anatomical structures derived from the prothoracic disc are generated and organized. This includes the transformation of a prothoracic imaginal disc from a monolayered epithelium in the larvae of holometabolous insects into the recognizable adult humerous and anterior spiracle.	tmpzr1t_l9r_go_relaxed.owl	prothoracic disc metamorphosis													biological_process											owl:Class	
GO:0051092	biolink:NamedThing	positive regulation of NF-kappaB transcription factor activity	Any process that activates or increases the frequency, rate or extent of activity of the transcription factor NF-kappaB.	tmpzr1t_l9r_go_relaxed.owl	activation of NF-kappaB transcription factor|NF-kappaB activation|activation of NF-kappaB													biological_process											owl:Class	
GO:0030877	biolink:NamedThing	beta-catenin destruction complex	A cytoplasmic protein complex containing glycogen synthase kinase-3-beta (GSK-3-beta), the adenomatous polyposis coli protein (APC), and the scaffolding protein axin, among others; phosphorylates beta-catenin, targets it for degradation by the proteasome.	tmpzr1t_l9r_go_relaxed.owl	APC-Axin-1-beta-catenin complex|23S APC complex|Axin-APC-beta-catenin-GSK3B complex|BDC|beta-catenin degradation complex					Note that the gene/protein name 'APC' should not be confused with the abbreviation for 'anaphase promoting complex'.						GO:0034747|GO:0034742		cellular_component											owl:Class	
GO:0002776	biolink:NamedThing	antimicrobial peptide secretion	The regulated release of an antimicrobial peptide from a cell or a tissue. Such peptides may have protective properties against bacteria, fungi, viruses, or protozoa.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0060561	biolink:NamedThing	apoptotic process involved in morphogenesis	Any apoptotic process that contributes to the shaping of an anatomical structure.	tmpzr1t_l9r_go_relaxed.owl	morphogenetic apoptosis|apoptosis involved in morphogenesis|apoptosis involved in development							dph	2009-04-28T09:17:27Z					biological_process											owl:Class	
GO:0090508	biolink:NamedThing	phenylethylamine biosynthetic process involved in synaptic transmission	The chemical reactions and pathways resulting in the formation of phenylethylamine that contribute to synaptic transmission.	tmpzr1t_l9r_go_relaxed.owl								tb	2012-11-15T15:10:23Z					biological_process											owl:Class	
GO:0090243	biolink:NamedThing	fibroblast growth factor receptor signaling pathway involved in somitogenesis	The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands that contributes to somitogenesis.	tmpzr1t_l9r_go_relaxed.owl	fibroblast growth factor receptor signalling pathway involved in somitogenesis							tb	2010-01-22T10:46:15Z					biological_process											owl:Class	
GO:0097282	biolink:NamedThing	immunoglobulin-mediated neutralization	The inhibition of an antigen's biological effects by antibody binding to it. An example is neutralization of diphtheria toxin by preventing its entry into human cells via the binding of antibody specific for diphtheria toxin.	tmpzr1t_l9r_go_relaxed.owl	antibody-mediated neutralization							pr	2012-03-26T01:55:24Z					biological_process											owl:Class	
GO:0051570	biolink:NamedThing	regulation of histone H3-K9 methylation	Any process that modulates the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 9 of histone H3.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1900087	biolink:NamedThing	positive regulation of G1/S transition of mitotic cell cycle	Any signalling pathway that increases or activates a cell cycle cyclin-dependent protein kinase to modulate the switch from G1 phase to S phase of the mitotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl	up regulation of G1/S transition of mitotic cell cycle|activation of G1/S transition of mitotic cell cycle|upregulation of G1/S transition of mitotic cell cycle|up-regulation of G1/S transition of mitotic cell cycle							rph	2012-02-08T12:24:39Z					biological_process											owl:Class	
GO:0061026	biolink:NamedThing	cardiac muscle tissue regeneration	The regrowth of cardiac muscle tissue to repair injured or damaged muscle fibers in the postnatal stage.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-02-09T08:25:51Z					biological_process											owl:Class	
GO:0006750	biolink:NamedThing	glutathione biosynthetic process	The chemical reactions and pathways resulting in the formation of glutathione, the tripeptide glutamylcysteinylglycine, which acts as a coenzyme for some enzymes and as an antioxidant in the protection of sulfhydryl groups in enzymes and other proteins.	tmpzr1t_l9r_go_relaxed.owl	glutathione anabolism|glutathione biosynthesis|glutathione synthesis|glutathione formation				MetaCyc:GLUTATHIONESYN-PWY									biological_process											owl:Class	
GO:0030859	biolink:NamedThing	polarized epithelial cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a polarized epithelial cell. The polarized epithelial cell can be any of the cells within an epithelium where the epithelial sheet is oriented with respect to the planar axis.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0044328	biolink:NamedThing	canonical Wnt signaling pathway involved in positive regulation of endothelial cell migration	The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes involved in the positive regulation of endothelial cell migration.	tmpzr1t_l9r_go_relaxed.owl	canonical Wnt receptor signalling pathway involved in positive regulation of endothelial cell migration|canonical Wnt receptor signaling pathway involved in positive regulation of endothelial cell migration							jl	2010-08-18T04:01:05Z					biological_process											owl:Class	
GO:0048318	biolink:NamedThing	axial mesoderm development	The process whose specific outcome is the progression of the axial mesoderm over time, from its formation to the mature structure. The axial mesoderm includes the prechordal mesoderm and the chordamesoderm. It gives rise to the prechordal plate and to the notochord.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0021995	biolink:NamedThing	neuropore closure	The process of joining together the neural folds at either end of the neural tube.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0052633	biolink:NamedThing	isocitrate hydro-lyase (cis-aconitate-forming) activity	Catalysis of the reaction: cis-aconitate + H2O = isocitrate.	tmpzr1t_l9r_go_relaxed.owl	cis-aconitase activity|citrate hydro-lyase activity|aconitate hydratase activity|citrate(isocitrate) hydro-lyase activity|citrate(isocitrate) hydro-lyase (cis-aconitate-forming)				RHEA:22144|MetaCyc:ACONITATEHYDR-RXN|KEGG_REACTION:R01900									molecular_function											owl:Class	
GO:0034495	biolink:NamedThing	protein storage vacuole lumen	The volume enclosed by the protein storage vacuole membrane.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0030658	biolink:NamedThing	transport vesicle membrane	The lipid bilayer surrounding a transport vesicle.	tmpzr1t_l9r_go_relaxed.owl	secretory vesicle membrane|constitutive secretory pathway transport vesicle membrane													cellular_component											owl:Class	
GO:0035272	biolink:NamedThing	exocrine system development	Progression of the exocrine system over time, from its formation to a mature structure. The exocrine system is a system of hormones and glands, where the glands secrete straight to a target site via ducts or tubes. The human exocrine system includes the salivary glands, sweat glands and many glands of the digestive system.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1900119	biolink:NamedThing	positive regulation of execution phase of apoptosis	Any process that activates or increases the frequency, rate or extent of execution phase of apoptosis.	tmpzr1t_l9r_go_relaxed.owl	upregulation of execution phase of apoptosis|activation of execution phase of apoptosis|up regulation of execution phase of apoptosis|up-regulation of execution phase of apoptosis							pr	2012-02-22T11:26:27Z					biological_process											owl:Class	
GO:1902733	biolink:NamedThing	regulation of growth plate cartilage chondrocyte differentiation	Any process that modulates the rate, frequency, or extent of the process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte that will contribute to the growth of a bone. A chondrocyte is a polymorphic cell that forms cartilage.	tmpzr1t_l9r_go_relaxed.owl								mr	2014-02-24T16:11:28Z					biological_process											owl:Class	
GO:0003418	biolink:NamedThing	growth plate cartilage chondrocyte differentiation	The process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte that will contribute to the growth of a bone. A chondrocyte is a polymorphic cell that forms cartilage.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-12-22T09:00:56Z					biological_process											owl:Class	
GO:1904634	biolink:NamedThing	negative regulation of glomerular visceral epithelial cell apoptotic process	Any process that stops, prevents or reduces the frequency, rate or extent of glomerular visceral epithelial cell apoptotic process.	tmpzr1t_l9r_go_relaxed.owl	downregulation of podocyte apoptosis|down-regulation of glomerular visceral epithelial cell apoptosis|down-regulation of glomerular visceral epithelial cell apoptotic process|down regulation of glomerular podocyte apoptosis|inhibition of glomerular podocyte apoptosis|inhibition of glomerular podocyte apoptotic process|negative regulation of glomerular visceral epithelial cell apoptosis|negative regulation of podocyte apoptotic process|down regulation of podocyte apoptotic process|down-regulation of podocyte apoptotic process|inhibition of podocyte apoptotic process|negative regulation of podocyte apoptosis|down-regulation of glomerular podocyte apoptotic process|negative regulation of glomerular podocyte apoptosis|inhibition of glomerular visceral epithelial cell apoptosis|down regulation of glomerular visceral epithelial cell apoptosis|down regulation of glomerular podocyte apoptotic process|downregulation of glomerular podocyte apoptosis|inhibition of podocyte apoptosis|downregulation of glomerular visceral epithelial cell apoptosis|inhibition of glomerular visceral epithelial cell apoptotic process|downregulation of glomerular podocyte apoptotic process|down regulation of podocyte apoptosis|negative regulation of glomerular podocyte apoptotic process|down-regulation of podocyte apoptosis|downregulation of glomerular visceral epithelial cell apoptotic process|down-regulation of glomerular podocyte apoptosis|downregulation of podocyte apoptotic process|down regulation of glomerular visceral epithelial cell apoptotic process							sl	2015-08-28T14:14:50Z					biological_process											owl:Class	
GO:1903210	biolink:NamedThing	glomerular visceral epithelial cell apoptotic process	Any apoptotic process in a glomerular visceral epithelial cell.	tmpzr1t_l9r_go_relaxed.owl	glomerular podocyte apoptosis|podocyte apoptotic process|glomerular visceral epithelial cell apoptosis|podocyte apoptosis|glomerular podocyte apoptotic process							sl	2014-07-23T17:07:55Z					biological_process											owl:Class	
GO:0044813	biolink:NamedThing	glycolytic fermentation via PFOR pathway	The glycolytic fermentation beginning with the anaerobic conversion of glucose to pyruvate by the glycolytic pathway, continuing with pyruvate:ferredoxin oxidoreductase (PFOR) activity. This pathway is found in strict anaerobes such as Clostridia species.	tmpzr1t_l9r_go_relaxed.owl								jl	2013-09-18T16:04:00Z					biological_process											owl:Class	
GO:0019164	biolink:NamedThing	pyruvate synthase activity	Catalysis of the reaction: pyruvate + CoA + 2 oxidized ferredoxin = acetyl-CoA + CO2 + 2 reduced ferredoxin + 2 H+.	tmpzr1t_l9r_go_relaxed.owl	pyruvate-ferredoxin reductase activity|pyruvate oxidoreductase activity|pyruvate:ferredoxin oxidoreductase activity|pyruvic-ferredoxin oxidoreductase activity|pyruvate synthetase activity|pyruvate:ferredoxin 2-oxidoreductase (CoA-acetylating)|PFOR				KEGG_REACTION:R01196|MetaCyc:PYRUFLAVREDUCT-RXN|EC:1.2.7.1|RHEA:12765							GO:0018696		molecular_function											owl:Class	
GO:0044842	biolink:NamedThing	gut granule lumen	The lumen of a gut granule, a lysosome-related organelle contained within the intestinal cells of the nematode C. elegans.	tmpzr1t_l9r_go_relaxed.owl								jl	2014-03-25T12:02:32Z					cellular_component											owl:Class	
GO:0072191	biolink:NamedThing	ureter smooth muscle development	The process whose specific outcome is the progression of smooth muscle in the ureter over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-03-01T01:48:53Z					biological_process											owl:Class	
GO:2001131	biolink:NamedThing	methane biosynthetic process from dimethyl sulfide	The chemical reactions and pathways resulting in the formation of a methane from a dimethyl sulfide.	tmpzr1t_l9r_go_relaxed.owl								jl	2011-10-13T10:44:31Z					biological_process											owl:Class	
GO:0106122	biolink:NamedThing	negative regulation of cobalamin metabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of a cobalamin metabolic process.	tmpzr1t_l9r_go_relaxed.owl								hjd	2018-05-01T18:12:48Z					biological_process											owl:Class	
GO:0009235	biolink:NamedThing	cobalamin metabolic process	The chemical reactions and pathways involving cobalamin (vitamin B12), a water-soluble vitamin characterized by possession of a corrin nucleus containing a cobalt atom.	tmpzr1t_l9r_go_relaxed.owl	vitamin B12 metabolism|cobalamin metabolism|vitamin B12 reduction|vitamin B12 metabolic process													biological_process											owl:Class	
GO:1902292	biolink:NamedThing	cell cycle DNA replication initiation	Any DNA replication initiation that is involved in cell cycle DNA replication.	tmpzr1t_l9r_go_relaxed.owl	DNA re-replication initiation involved in cell cycle DNA replication|DNA-dependent DNA replication initiation involved in cell cycle DNA replication|DNA endoreduplication initiation involved in cell cycle DNA replication|DNA replication initiation involved in cell cycle DNA replication							jl	2013-07-09T16:05:54Z					biological_process											owl:Class	
GO:0021818	biolink:NamedThing	modulation of the microfilament cytoskeleton involved in cell locomotion in cerebral cortex radial glia guided migration	The changes in the actin cytoskeleton that are necessary for the movement of cells along radial glial cells as a component of the process of cerebral cortex glial-mediated radial cell migration.	tmpzr1t_l9r_go_relaxed.owl	modulation of the microfilament cytoskeleton involved in cell locomotion in cerebral cortex glial-mediated radial migration													biological_process											owl:Class	
GO:1903870	biolink:NamedThing	positive regulation of methylenetetrahydrofolate reductase (NAD(P)H) activity	Any process that activates or increases the frequency, rate or extent of methylenetetrahydrofolate reductase (NAD(P)H) activity.	tmpzr1t_l9r_go_relaxed.owl	upregulation of 5,10-CH2-H4folate reductase activity|positive regulation of 5,10-methylenetetrahydrofolate reductase (NADPH) activity|upregulation of N5,10-methylenetetrahydrofolate reductase activity|positive regulation of 5-methyltetrahydrofolate:NADP(+) oxidoreductase activity|up regulation of 5-methyltetrahydrofolate:(acceptor) oxidoreductase activity|up-regulation of 5-methyltetrahydrofolate:(acceptor) oxidoreductase activity|activation of 5-methyltetrahydrofolate:NADP+ oxidoreductase activity|positive regulation of 5-methyltetrahydrofolate:NAD(+) oxidoreductase activity|upregulation of methylenetetrahydrofolate (reduced riboflavin adenine dinucleotide) reductase activity|up regulation of methylenetetrahydrofolate reductase [NAD(P)H]|upregulation of N5,N10-methylenetetrahydrofolate reductase activity|positive regulation of MetF|up-regulation of methylenetetrahydrofolate reductase (NADPH(2)) activity|upregulation of methylenetetrahydrofolate reductase [NAD(P)H]|activation of 5-methyltetrahydrofolate:NAD+ oxidoreductase activity|up-regulation of 5,10-CH2-H4folate reductase activity|activation of 5-methyltetrahydrofolate:NADP(+) oxidoreductase activity|upregulation of 5-methyltetrahydrofolate:NAD+ oxidoreductase activity|up-regulation of MetF|up regulation of N5,10-methylenetetrahydrofolate reductase activity|up regulation of N5,N10-methylenetetrahydrofolate reductase activity|up regulation of 5-methyltetrahydrofolate:NADP+ oxidoreductase activity|upregulation of methylenetetrahydrofolate (reduced nicotinamide adenine dinucleotide phosphate) reductase activity|activation of methylenetetrahydrofolate reductase (NADPH2)|up regulation of 5,10-CH(2)-H(4)folate reductase activity|activation of 5,10-CH2-H4folate reductase activity|upregulation of 5,10-methylenetetrahydrofolate reductase (FADH(2)) activity|upregulation of 5-methyltetrahydrofolate:NAD(+) oxidoreductase activity|activation of MetF|positive regulation of N5,10-methylenetetrahydrofolate reductase activity|positive regulation of 5,10-methylenetetrahydrofolate reductase (FADH2) activity|upregulation of MetF|up-regulation of 5,10-methylenetetrahydrofolate reductase (FADH(2)) activity|activation of 5,10-methylenetetrahydropteroylglutamate reductase activity|up-regulation of 5-methyltetrahydrofolate:NADP+ oxidoreductase activity|activation of 5,10-methylenetetrahydrofolate reductase (FADH) activity|upregulation of methylenetetrahydrofolate reductase (NADPH2)|upregulation of 5-methyltetrahydrofolate:(acceptor) oxidoreductase activity|activation of 5,10-methylenetetrahydrofolate reductase (FADH2) activity|up regulation of 5-methyltetrahydrofolate:NADP(+) oxidoreductase activity|positive regulation of methylenetetrahydrofolate (reduced riboflavin adenine dinucleotide) reductase activity|activation of 5-methyltetrahydrofolate:NAD oxidoreductase activity|up regulation of 5,10-CH2-H4folate reductase activity|up regulation of MetF|activation of 5,10-CH(2)-H(4)folate reductase activity|upregulation of 5,10-methylenetetrahydrofolate reductase (FADH) activity|up regulation of methylenetetrahydrofolate (reduced riboflavin adenine dinucleotide) reductase activity|up-regulation of 5-methyltetrahydrofolate:NAD(P)+ oxidoreductase activity|up-regulation of methylenetetrahydrofolate (reduced nicotinamide adenine dinucleotide phosphate) reductase activity|up-regulation of 5,10-methylenetetrahydrofolate reductase (FADH) activity|upregulation of 5,10-methylenetetrahydropteroylglutamate reductase activity|positive regulation of 5-methyltetrahydrofolate:NAD(P)+ oxidoreductase activity|activation of 5,10-methylenetetrahydrofolate reductase (FADH(2)) activity|up regulation of 5,10-methylenetetrahydrofolate reductase (FADH) activity|upregulation of 5-methyltetrahydrofolate:NADP(+) oxidoreductase activity|up regulation of 5-methyltetrahydrofolate:NAD(+) oxidoreductase activity|up regulation of methylenetetrahydrofolate reductase (NADPH2)|positive regulation of 5,10-CH2-H4folate reductase activity|upregulation of methylenetetrahydrofolate reductase (NADPH(2)) activity|up-regulation of 5-methyltetrahydrofolate:NAD(+) oxidoreductase activity|up-regulation of 5,10-CH(2)-H(4)folate reductase activity|up-regulation of 5-methyltetrahydrofolate:NADP(+) oxidoreductase activity|positive regulation of methylenetetrahydrofolate (reduced nicotinamide adenine dinucleotide phosphate) reductase activity|up-regulation of 5-methyltetrahydrofolate:NAD+ oxidoreductase activity|activation of 5-methyltetrahydrofolate:NAD(P)+ oxidoreductase activity|upregulation of methylenetetrahydrofolate reductase (NAD(P)H) activity|upregulation of 5,10-methylenetetrahydrofolate reductase (FADH2) activity|up-regulation of methylenetetrahydrofolate (reduced riboflavin adenine dinucleotide) reductase activity|positive regulation of 5,10-methylenetetrahydropteroylglutamate reductase activity|activation of N5,N10-methylenetetrahydrofolate reductase activity|activation of methylenetetrahydrofolate reductase (NAD(P)H) activity|activation of 5-methyltetrahydrofolate:NAD(+) oxidoreductase activity|up regulation of 5,10-methylenetetrahydrofolate reductase (FADH2) activity|up regulation of methylenetetrahydrofolate reductase (NADPH(2)) activity|up regulation of methylenetetrahydrofolate (reduced nicotinamide adenine dinucleotide phosphate) reductase activity|up regulation of methylenetetrahydrofolate reductase (NAD(P)H) activity|up-regulation of methylenetetrahydrofolate reductase (NADPH2)|activation of methylenetetrahydrofolate (reduced riboflavin adenine dinucleotide) reductase activity|activation of 5-methyltetrahydrofolate:(acceptor) oxidoreductase activity|activation of N5,10-methylenetetrahydrofolate reductase activity|up regulation of 5-methyltetrahydrofolate:NAD(P)+ oxidoreductase activity|upregulation of 5,10-methylenetetrahydrofolate reductase (NADPH) activity|upregulation of 5,10-CH(2)-H(4)folate reductase activity|activation of 5,10-methylenetetrahydrofolate reductase (NADPH) activity|up-regulation of 5-methyltetrahydrofolate:NAD oxidoreductase activity|positive regulation of 5,10-methylenetetrahydrofolate reductase (FADH) activity|up regulation of 5,10-methylenetetrahydrofolate reductase (FADH(2)) activity|activation of methylenetetrahydrofolate reductase [NAD(P)H]|positive regulation of methylenetetrahydrofolate reductase (NADPH(2)) activity|upregulation of 5-methyltetrahydrofolate:NAD oxidoreductase activity|positive regulation of 5,10-CH(2)-H(4)folate reductase activity|upregulation of 5-methyltetrahydrofolate:NAD(P)+ oxidoreductase activity|up-regulation of N5,10-methylenetetrahydrofolate reductase activity|activation of methylenetetrahydrofolate reductase (NADPH(2)) activity|positive regulation of 5-methyltetrahydrofolate:NAD+ oxidoreductase activity|up-regulation of 5,10-methylenetetrahydropteroylglutamate reductase activity|up regulation of 5,10-methylenetetrahydrofolate reductase (NADPH) activity|up-regulation of 5,10-methylenetetrahydrofolate reductase (FADH2) activity|up regulation of 5,10-methylenetetrahydropteroylglutamate reductase activity|activation of methylenetetrahydrofolate (reduced nicotinamide adenine dinucleotide phosphate) reductase activity|positive regulation of methylenetetrahydrofolate reductase (NADPH2)|up-regulation of methylenetetrahydrofolate reductase [NAD(P)H]|positive regulation of 5,10-methylenetetrahydrofolate reductase (FADH(2)) activity|up-regulation of 5,10-methylenetetrahydrofolate reductase (NADPH) activity|positive regulation of 5-methyltetrahydrofolate:(acceptor) oxidoreductase activity|positive regulation of N5,N10-methylenetetrahydrofolate reductase activity|upregulation of 5-methyltetrahydrofolate:NADP+ oxidoreductase activity|up-regulation of N5,N10-methylenetetrahydrofolate reductase activity|up regulation of 5-methyltetrahydrofolate:NAD oxidoreductase activity|up regulation of 5-methyltetrahydrofolate:NAD+ oxidoreductase activity|positive regulation of methylenetetrahydrofolate reductase [NAD(P)H]|positive regulation of 5-methyltetrahydrofolate:NAD oxidoreductase activity|up-regulation of methylenetetrahydrofolate reductase (NAD(P)H) activity|positive regulation of 5-methyltetrahydrofolate:NADP+ oxidoreductase activity							rph	2015-02-05T13:26:33Z					biological_process											owl:Class	
GO:0004489	biolink:NamedThing	methylenetetrahydrofolate reductase (NAD(P)H) activity	Catalysis of the reaction: 5-methyltetrahydrofolate + NAD(P)+ = 5,10-methylenetetrahydrofolate + NAD(P)H + H+.	tmpzr1t_l9r_go_relaxed.owl	5,10-methylenetetrahydrofolate reductase (FADH) activity|5-methyltetrahydrofolate:NADP(+) oxidoreductase activity|5-methyltetrahydrofolate:NADP+ oxidoreductase activity|5-methyltetrahydrofolate:NAD(P)+ oxidoreductase activity|N(5,10)-methylenetetrahydrofolate reductase activity|methylenetetrahydrofolate reductase (NADPH2)|5,10-methylenetetrahydrofolic acid reductase activity|5-methyltetrahydrofolate:NAD oxidoreductase activity|5-methyltetrahydrofolate:NAD(+) oxidoreductase activity|5,10-methylenetetrahydrofolate reductase (FADH(2)) activity|MetF|methylenetetrahydrofolate (reduced nicotinamide adenine dinucleotide phosphate) reductase activity|5,10-methylenetetrahydropteroylglutamate reductase activity|5,10-methylenetetrahydrofolate reductase (NADPH) activity|N5,10-methylenetetrahydrofolate reductase activity|methylenetetrahydrofolic acid reductase activity|methylenetetrahydrofolate reductase (NADPH(2)) activity|5-methyltetrahydrofolate:NAD+ oxidoreductase activity|MTHFR activity|methylenetetrahydrofolate reductase activity|methylenetetrahydrofolate reductase [NAD(P)H]|methylenetetrahydrofolate (reduced riboflavin adenine dinucleotide) reductase activity|N(5),N(10)-methylenetetrahydrofolate reductase activity|5,10-CH(2)-H(4)folate reductase activity|5,10-CH2-H4folate reductase activity|5,10-methylenetetrahydrofolate reductase activity|5,10-methylenetetrahydrofolate reductase (FADH2) activity|N5,N10-methylenetetrahydrofolate reductase activity|5-methyltetrahydrofolate:(acceptor) oxidoreductase activity				KEGG_REACTION:R07168|EC:1.5.1.20|MetaCyc:1.5.1.20-RXN|Reactome:R-HSA-200676|KEGG_REACTION:R01224							GO:0008702		molecular_function											owl:Class	
GO:0048783	biolink:NamedThing	positive regulation of cyanophore differentiation	Any process that activates or increases the frequency, rate or extent of cyanophore differentiation.	tmpzr1t_l9r_go_relaxed.owl	up regulation of cyanophore differentiation|stimulation of cyanophore differentiation|activation of cyanophore differentiation|upregulation of cyanophore differentiation|up-regulation of cyanophore differentiation													biological_process											owl:Class	
GO:0048774	biolink:NamedThing	cyanophore differentiation	The process in which a relatively unspecialized cell acquires the specialized features of a cyanophore cell. Cyanophores are pigment cells derived from the neural crest. They contain a blue pigment of unknown chemical composition. The pigment is stored in fibrous organelles termed cyanosomes.	tmpzr1t_l9r_go_relaxed.owl	cyanophore cell differentiation													biological_process											owl:Class	
GO:0098591	biolink:NamedThing	external side of apical plasma membrane	The leaflet the apical region of the plasma membrane that faces away from the cytoplasm and any proteins embedded or anchored in it or attached to its surface.	tmpzr1t_l9r_go_relaxed.owl								dos	2014-03-06T12:04:33Z					cellular_component											owl:Class	
GO:0000238	biolink:NamedThing	zygotene	The cell cycle phase which follows leptotene during prophase I of meiosis, and during which each chromosome pairs with its homolog; the two become aligned and crossing over may occur.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Meiosis#Zygotene|Wikipedia:Zygotene	Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).								biological_process											owl:Class	
GO:0007128	biolink:NamedThing	meiotic prophase I	The cell cycle phase which is the first stage of meiosis I and during which chromosomes condense and the two daughter centrioles and their asters migrate toward the poles of the cell.	tmpzr1t_l9r_go_relaxed.owl						Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).								biological_process											owl:Class	
GO:0033148	biolink:NamedThing	positive regulation of intracellular estrogen receptor signaling pathway	Any process that activates or increases the frequency, rate or extent of the activity of an intracellular estrogen receptor signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of estrogen receptor signaling pathway|positive regulation of estrogen receptor signalling pathway													biological_process											owl:Class	
GO:0060965	biolink:NamedThing	negative regulation of gene silencing by miRNA	Any process that decreases the rate, frequency, or extent of gene silencing by miRNA.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of gene silencing by microRNA							dph	2009-10-05T03:14:14Z					biological_process											owl:Class	
GO:0048927	biolink:NamedThing	posterior lateral line neuromast support cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a posterior lateral line neuromast support cell. Support cells are non-sensory cells of the neuromast that extend between the sensory hair cells from the basement membrane to the apical surface; they are surrounded by mantle cells.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0048919	biolink:NamedThing	posterior lateral line neuromast development	The process whose specific outcome is the progression of the posterior lateral line neuromast over time, from its formation to the mature structure. The neuromast is the sensory receptor of the anterior lateral line system and is composed of a population of sensory hair cells, and nonsensory supporting cells and mantle cells. Neuromast are located superficially on the epithelium or in lateral line canals.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0097103	biolink:NamedThing	endothelial stalk cell fate specification	The process involved in the specification of identity of an endothelial stalk cell. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment. An endothelial stalk cell is a specialized endothelial cell which follows behind the tip cell of an angiogenic sprout.	tmpzr1t_l9r_go_relaxed.owl	angiogenic stalk cell fate specification							pr	2011-07-27T10:32:38Z					biological_process											owl:Class	
GO:0014831	biolink:NamedThing	gastro-intestinal system smooth muscle contraction	A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the gastro-intestinal system. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The gastro-intestinal system generally refers to the digestive structures stretching from the mouth to anus, but does not include the accessory glandular organs (liver, pancreas and biliary tract).	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0060008	biolink:NamedThing	Sertoli cell differentiation	The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a Sertoli cell. A Sertoli cell is a supporting cell projecting inward from the basement membrane of seminiferous tubules.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0000995	biolink:NamedThing	RNA polymerase III general transcription initiation factor activity	A general transcription initiation factor activity that contributes to transcription start site selection and transcription initiation of genes transcribed by RNA polymerase III. Factors required for RNA polymerase III transcription initiation include TFIIIA, TFIIIB and TFIIIC. A general transcription initiation factor activity that contributes to transcription start site selection and transcription initiation of genes transcribed by RNA polymerase III. Factors required for RNA polymerase III transcription initiation include TFIIIA, TFIIIB and TFIIIC. RNA polymerase III transcribes genes encoding short RNAs, including tRNAs, 5S rRNA, U6 snRNA, the short ncRNA component of RNases P, the mitochondrial RNA processing (MRP) RNA, the signal recognition particle SRP RNA, and in higher eukaryotes a number of micro and other small RNAs, though there is some variability across species as to whether a given small noncoding RNA is transcribed by RNA polymerase II or RNA polymerase III.	tmpzr1t_l9r_go_relaxed.owl	transcription factor activity, core RNA polymerase III binding|RNA polymerase III general initiation factor activity|RNA polymerase III transcription factor activity, sequence-specific DNA binding|core RNA polymerase III binding transcription factor activity|sequence-specific DNA binding RNA polymerase III transcription factor activity	https://github.com/geneontology/go-ontology/issues/15789|https://github.com/geneontology/go-ontology/issues/20253						krc	2010-08-23T03:41:48Z			GO:0001034		molecular_function											owl:Class	
GO:0060774	biolink:NamedThing	auxin mediated signaling pathway involved in phyllotactic patterning	The series of molecular signals generated in response to detection of auxin that contributes to the radial pattern formation process resulting in the formation of leaf or flower primordia around the center of a shoot apical meristem.	tmpzr1t_l9r_go_relaxed.owl	auxin mediated signalling pathway involved in phyllotactic patterning							dph	2009-07-25T06:31:13Z					biological_process											owl:Class	
GO:0060389	biolink:NamedThing	pathway-restricted SMAD protein phosphorylation	The process of introducing a phosphate group on to a pathway restricted SMAD protein. A pathway restricted SMAD protein is an effector protein that acts directly downstream of the transforming growth factor family receptor.	tmpzr1t_l9r_go_relaxed.owl	receptor regulated SMAD protein phosphorylation|receptor-regulated SMAD protein phosphorylation|R-SMAD protein phosphorylation|pathway restricted SMAD protein phosphorylation													biological_process											owl:Class	
GO:0032254	biolink:NamedThing	establishment of secretory granule localization	The directed movement of a secretory granule to a specific location.	tmpzr1t_l9r_go_relaxed.owl	establishment of secretory granule localisation													biological_process											owl:Class	
GO:0072253	biolink:NamedThing	metanephric juxtaglomerulus cell fate commitment	The process in which the developmental fate of a cell becomes restricted such that it will develop into a metanephric juxtaglomerulus cell.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-03-19T03:55:47Z					biological_process											owl:Class	
GO:1900256	biolink:NamedThing	regulation of beta1-adrenergic receptor activity	Any process that modulates the frequency, rate or extent of beta1-adrenergic receptor activity.	tmpzr1t_l9r_go_relaxed.owl	regulation of beta1 adrenoceptor							tb	2012-04-03T10:59:21Z					biological_process											owl:Class	
GO:0019813	biolink:NamedThing	type III site-specific deoxyribonuclease complex	A heterodimeric enzyme complex composed of two subunits, Res and Mod, that functions as an endonuclease and cleaves DNA. Cleavage will only occur when there are two un-methylated copies of a specific recognition site in an inverse orientation on the DNA. Cleavage occurs at a specific distance away from one of the recognition sites. The Mod subunit can act alone as a methyltansferase. DNA restriction systems such as this are used by bacteria to defend against phage and other foreign DNA that may enter a cell.	tmpzr1t_l9r_go_relaxed.owl	type III restriction enzyme complex													cellular_component											owl:Class	
GO:0060918	biolink:NamedThing	auxin transport	The directed movement of auxin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-09-28T02:44:54Z					biological_process											owl:Class	
GO:0006369	biolink:NamedThing	termination of RNA polymerase II transcription	The process in which the synthesis of an RNA molecule by RNA polymerase II using a DNA template is completed.	tmpzr1t_l9r_go_relaxed.owl	RNA 3'-end formation by RNA polymerase II|RNA polymerase II transcription termination|RNA polymerase II transcription termination factor activity|transcription termination from RNA polymerase II promoter|transcription termination from Pol II promoter											GO:0019224		biological_process											owl:Class	
GO:0016459	biolink:NamedThing	myosin complex	A protein complex, formed of one or more myosin heavy chains plus associated light chains and other proteins, that functions as a molecular motor; uses the energy of ATP hydrolysis to move actin filaments or to move vesicles or other cargo on fixed actin filaments; has magnesium-ATPase activity and binds actin. Myosin classes are distinguished based on sequence features of the motor, or head, domain, but also have distinct tail regions that are believed to bind specific cargoes.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:2000880	biolink:NamedThing	positive regulation of dipeptide transport	Any process that activates or increases the frequency, rate or extent of dipeptide transport.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-07-27T02:55:24Z					biological_process											owl:Class	
GO:0042938	biolink:NamedThing	dipeptide transport	The directed movement of a dipeptide, a combination of two amino acids by means of a peptide (-CO-NH-) link, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0090182	biolink:NamedThing	regulation of secretion of lysosomal enzymes	Any process that modulates the rate, frequency or extent of secretion of lysosomal enzymes, the controlled release of lysosomal enzymes by a cell.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-12-18T10:40:46Z					biological_process											owl:Class	
GO:0000324	biolink:NamedThing	fungal-type vacuole	A vacuole that has both lytic and storage functions. The fungal vacuole is a large, membrane-bounded organelle that functions as a reservoir for the storage of small molecules (including polyphosphate, amino acids, several divalent cations (e.g. calcium), other ions, and other small molecules) as well as being the primary compartment for degradation. It is an acidic compartment, containing an ensemble of acid hydrolases. At least in S. cerevisiae, there are indications that the morphology of the vacuole is variable and correlated with the cell cycle, with logarithmically growing cells having a multilobed, reticulated vacuole, while stationary phase cells contain a single large structure.	tmpzr1t_l9r_go_relaxed.owl	vacuole, cell cycle-correlated morphology													cellular_component											owl:Class	
GO:0090051	biolink:NamedThing	negative regulation of cell migration involved in sprouting angiogenesis	Any process that decreases the frequency, rate or extent of cell migration involved in sprouting angiogenesis. Cell migration involved in sprouting angiogenesis is the orderly movement of endothelial cells into the extracellular matrix in order to form new blood vessels contributing to the process of sprouting angiogenesis.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-08-07T10:42:00Z					biological_process											owl:Class	
GO:0140664	biolink:NamedThing	ATP-dependent DNA damage sensor activity	A molecule that recognises toxic DNA structures, and initiates a signalling response, driven by ATP hydrolysis.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/21662						pg	2021-06-19T16:37:21Z					molecular_function											owl:Class	
GO:0016887	biolink:NamedThing	ATP hydrolysis activity	Catalysis of the reaction: ATP + H2O = ADP + H+ Pi. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient.	tmpzr1t_l9r_go_relaxed.owl	ATP hydrolase activity|ATP phosphohydrolase activity|ATP monophosphatase activity|adenosinetriphosphatase activity|adenosine 5'-triphosphatase activity|adenosine triphosphatase activity	https://github.com/geneontology/go-ontology/issues/21612|https://github.com/geneontology/go-ontology/issues/20498|https://github.com/geneontology/go-ontology/issues/22371|https://github.com/geneontology/go-ontology/issues/19078			Reactome:R-HSA-5618093|Reactome:R-HSA-8939203|Reactome:R-HSA-9038161|Reactome:R-HSA-8868658|Reactome:R-HSA-5694425|Reactome:R-HSA-9706399|Reactome:R-HSA-416985|Reactome:R-HSA-72139|Reactome:R-HSA-917693|Reactome:R-HSA-6814678|Reactome:R-HSA-9668415|Reactome:R-HSA-6809015|Reactome:R-HSA-159101|Reactome:R-HSA-6814670|Reactome:R-HSA-3371422|Reactome:R-HSA-8847638|Reactome:R-HSA-9609860|Reactome:R-HSA-6811422|RHEA:13065|Reactome:R-HSA-5654989|Reactome:R-HSA-6814683	Note that this term is meant to specifically represent the ATPase activity of proteins using ATPase as a source of energy to drive a reaction. If possible, gene products should also be annotated to a child of 'ATP-dependent activity ; GO:0140657', to capture their overall function.						GO:0004002|GO:0042623		molecular_function											owl:Class	
GO:0032587	biolink:NamedThing	ruffle membrane	The portion of the plasma membrane surrounding a ruffle.	tmpzr1t_l9r_go_relaxed.owl	membrane ruffle													cellular_component											owl:Class	
GO:0014817	biolink:NamedThing	skeletal muscle satellite cell fate specification	The process in which a cell becomes capable of differentiating autonomously into a skeletal muscle satellite cell in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0014813	biolink:NamedThing	skeletal muscle satellite cell commitment	The process in which the developmental fate of a cell becomes restricted such that it will develop into a satellite cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0034141	biolink:NamedThing	positive regulation of toll-like receptor 3 signaling pathway	Any process that activates or increases the frequency, rate, or extent of toll-like receptor 3 signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of TLR3 signaling pathway|positive regulation of toll-like receptor 3 signalling pathway													biological_process											owl:Class	
GO:0030672	biolink:NamedThing	synaptic vesicle membrane	The lipid bilayer surrounding a synaptic vesicle.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:1905338	biolink:NamedThing	negative regulation of cohesin unloading	Any process that stops, prevents or reduces the frequency, rate or extent of cohesin unloading.	tmpzr1t_l9r_go_relaxed.owl	downregulation of cohesin unloading|inhibition of cohesin unloading|down-regulation of cohesin unloading|down regulation of cohesin unloading							vw	2016-07-26T16:23:58Z					biological_process											owl:Class	
GO:0070316	biolink:NamedThing	regulation of G0 to G1 transition	A cell cycle process that modulates the rate or extent of the transition from the G0 quiescent state to the G1 phase.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0045023	biolink:NamedThing	G0 to G1 transition	The mitotic cell cycle phase transition whose occurrence commits the cell from the G0 quiescent state to the G1 phase. Under certain conditions, cells exit the cell cycle during G1 and remain in the G0 state as nongrowing, non-dividing (quiescent) cells. Appropriate stimulation of such cells induces them to return to G1 and resume growth and division. The G0 to G1 transition is accompanied by many changes in the program of gene expression.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0071808	biolink:NamedThing	satellite fibril	An axoneme part that is found in the flagella of mammalian sperm and is located in the middle piece between the outer dense fibers (on the concave side of outer dense fibers as seen in cross-section).	tmpzr1t_l9r_go_relaxed.owl								mah	2010-09-03T03:42:14Z					cellular_component											owl:Class	
GO:0046660	biolink:NamedThing	female sex differentiation	The establishment of the sex of a female organism by physical differentiation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0005822	biolink:NamedThing	inner plaque of spindle pole body	One of three laminate structures that form the spindle pole body; the inner plaque is in the nucleus.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0071584	biolink:NamedThing	negative regulation of zinc ion transmembrane import	Any process that stops, prevents, or reduces the frequency, rate or extent of zinc ion import.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-01-28T03:17:21Z					biological_process											owl:Class	
GO:0001646	biolink:NamedThing	cAMP receptor activity	Combining with cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	3',5'-cAMP receptor activity|class E G-protein coupled receptor|class E G protein coupled receptor|adenosine 3',5'-cyclophosphate receptor activity|3',5' cAMP receptor activity|class E GPCR|cyclic AMP receptor activity											GO:0001644		molecular_function											owl:Class	
GO:1905272	biolink:NamedThing	negative regulation of proton-transporting ATP synthase activity, rotational mechanism	Any process that stops, prevents or reduces the frequency, rate or extent of proton-transporting ATP synthase activity, rotational mechanism.	tmpzr1t_l9r_go_relaxed.owl	down regulation of H+-transporting ATP synthase activity|down-regulation of hydrogen ion transporting two-sector ATPase activity|inhibition of H+-transporting ATP synthase activity|down-regulation of H+-transporting ATP synthase activity|inhibition of proton-transporting ATP synthase activity, rotational mechanism|down-regulation of hydrogen ion translocating F-type ATPase activity|down-regulation of proton-transporting ATP synthase activity, rotational mechanism|down regulation of proton-transporting ATP synthase activity, rotational mechanism|negative regulation of hydrogen ion translocating F-type ATPase activity|inhibition of hydrogen ion transporting ATP synthase activity, rotational mechanism|downregulation of hydrogen ion translocating F-type ATPase activity|down regulation of hydrogen ion transporting ATP synthase activity, rotational mechanism|down regulation of hydrogen ion translocating F-type ATPase activity|downregulation of proton-transporting ATP synthase activity, rotational mechanism|downregulation of H+-transporting ATP synthase activity|downregulation of hydrogen ion transporting two-sector ATPase activity|negative regulation of H+-transporting ATP synthase activity|negative regulation of hydrogen ion transporting two-sector ATPase activity|inhibition of hydrogen ion transporting two-sector ATPase activity|downregulation of hydrogen ion transporting ATP synthase activity, rotational mechanism|down-regulation of hydrogen ion transporting ATP synthase activity, rotational mechanism|inhibition of hydrogen ion translocating F-type ATPase activity|down regulation of hydrogen ion transporting two-sector ATPase activity|negative regulation of hydrogen ion transporting ATP synthase activity, rotational mechanism							als	2016-06-16T12:09:57Z					biological_process											owl:Class	
GO:0042052	biolink:NamedThing	rhabdomere development	The assembly and arrangement of a rhabdomere within a cell. The rhabdomere is the organelle on the apical surface of a photoreceptor cell that contains the visual pigments.	tmpzr1t_l9r_go_relaxed.owl	rhabdomere organization													biological_process											owl:Class	
GO:0060038	biolink:NamedThing	cardiac muscle cell proliferation	The expansion of a cardiac muscle cell population by cell division.	tmpzr1t_l9r_go_relaxed.owl	cardiac myocyte proliferation|cardiomyocyte proliferation|heart muscle cell proliferation													biological_process											owl:Class	
GO:0035144	biolink:NamedThing	anal fin morphogenesis	The process in which the anatomical structures of the anal fin are generated and organized. An anal fin is an unpaired medial fin on the ventral aspect near the caudal end of a fish, which provides lateral stability while swimming.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0016575	biolink:NamedThing	histone deacetylation	The modification of histones by removal of acetyl groups.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1904241	biolink:NamedThing	positive regulation of VCP-NPL4-UFD1 AAA ATPase complex assembly	Any process that activates or increases the frequency, rate or extent of VCP-NPL4-UFD1 AAA ATPase complex assembly.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of Cdc48p-Npl4p-Ufd1p AAA ATPase complex assembly|positive regulation of Cdc48p-Npl4p-Ufd1p AAA ATPase complex assembly|activation of Cdc48p-Npl4p-Ufd1p AAA ATPase complex assembly|upregulation of VCP-NPL4-UFD1 AAA ATPase complex formation|activation of p97-Ufd1-Npl4 complex assembly|up regulation of VCP-NPL4-UFD1 AAA ATPase complex formation|positive regulation of p97-Ufd1-Npl4 complex formation|upregulation of p97-Ufd1-Npl4 complex assembly|upregulation of Cdc48p-Npl4p-Ufd1p AAA ATPase complex assembly|activation of VCP-NPL4-UFD1 AAA ATPase complex formation|up-regulation of Cdc48p-Npl4p-Ufd1p AAA ATPase complex formation|up regulation of p97-Ufd1-Npl4 complex formation|up regulation of Cdc48p-Npl4p-Ufd1p AAA ATPase complex formation|up regulation of Cdc48p-Npl4p-Ufd1p AAA ATPase complex assembly|upregulation of Cdc48p-Npl4p-Ufd1p AAA ATPase complex formation|positive regulation of Cdc48p-Npl4p-Ufd1p AAA ATPase complex formation|up regulation of p97-Ufd1-Npl4 complex assembly|positive regulation of VCP-NPL4-UFD1 AAA ATPase complex formation|up-regulation of VCP-NPL4-UFD1 AAA ATPase complex formation|up-regulation of VCP-NPL4-UFD1 AAA ATPase complex assembly|upregulation of p97-Ufd1-Npl4 complex formation|activation of VCP-NPL4-UFD1 AAA ATPase complex assembly|up-regulation of p97-Ufd1-Npl4 complex formation|positive regulation of p97-Ufd1-Npl4 complex assembly|up-regulation of p97-Ufd1-Npl4 complex assembly|upregulation of VCP-NPL4-UFD1 AAA ATPase complex assembly|activation of p97-Ufd1-Npl4 complex formation|activation of Cdc48p-Npl4p-Ufd1p AAA ATPase complex formation|up regulation of VCP-NPL4-UFD1 AAA ATPase complex assembly							bf	2015-05-18T09:50:34Z					biological_process											owl:Class	
GO:0060937	biolink:NamedThing	cardiac fibroblast cell fate commitment	The commitment of cells to a cardiac fibroblast fate and their capacity to differentiate into cardiac fibroblast cells. A cardiac fibroblast is a connective tissue cell in the heart which secretes an extracellular matrix rich in collagen and other macromolecules.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-09-29T01:24:59Z					biological_process											owl:Class	
GO:1903548	biolink:NamedThing	negative regulation of growth hormone activity	Any process that stops, prevents or reduces the frequency, rate or extent of growth hormone activity.	tmpzr1t_l9r_go_relaxed.owl	downregulation of growth hormone activity|downregulation of GH activity|down-regulation of growth hormone activity|down regulation of growth hormone activity|down-regulation of pituitary growth hormone activity|down-regulation of placental growth hormone activity|inhibition of placental growth hormone activity|negative regulation of GH activity|inhibition of pituitary growth hormone activity|inhibition of growth hormone activity|down regulation of GH activity|down regulation of pituitary growth hormone activity|inhibition of GH activity|down regulation of placental growth hormone activity|downregulation of pituitary growth hormone activity|down-regulation of GH activity|negative regulation of placental growth hormone activity|downregulation of placental growth hormone activity|negative regulation of pituitary growth hormone activity							mr	2014-10-20T15:18:45Z					biological_process											owl:Class	
GO:0070186	biolink:NamedThing	growth hormone activity	The action characteristic of growth hormone, a peptide hormone that is secreted by the anterior pituitary or the placenta into the circulation, and binds to membrane receptors in target tissues to stimulate body growth.	tmpzr1t_l9r_go_relaxed.owl	pituitary growth hormone activity|GH activity|placental growth hormone activity													molecular_function											owl:Class	
GO:0005242	biolink:NamedThing	inward rectifier potassium channel activity	Enables the transmembrane transfer of a potassium ion by an inwardly-rectifying voltage-gated channel. An inwardly rectifying current-voltage relation is one where at any given driving force the inward flow of K+ ions exceeds the outward flow for the opposite driving force. The inward-rectification is due to a voltage-dependent block of the channel pore by a specific ligand or ligands, and as a result the macroscopic conductance depends on the difference between membrane voltage and the K+ equilibrium potential rather than on membrane voltage itself.	tmpzr1t_l9r_go_relaxed.owl	Kir channel activity				Reactome:R-HSA-1296045|Reactome:R-HSA-1369017|Reactome:R-HSA-5678418|Reactome:R-HSA-1296046|Reactome:R-HSA-5678261									molecular_function											owl:Class	
GO:0009688	biolink:NamedThing	abscisic acid biosynthetic process	The chemical reactions and pathways resulting in the formation of abscisic acid, 5-(1-hydroxy-2,6,6,trimethyl-4-oxocyclohex-2-en-1-y1)-3-methylpenta-2,4-dienoic acid.	tmpzr1t_l9r_go_relaxed.owl	abscisic acid anabolism|abscisic acid formation|abscisic acid synthesis|abscisic acid biosynthesis				MetaCyc:PWY-695									biological_process											owl:Class	
GO:1904132	biolink:NamedThing	positive regulation of convergent extension involved in neural plate elongation	Any process that activates or increases the frequency, rate or extent of convergent extension involved in neural plate elongation.	tmpzr1t_l9r_go_relaxed.owl	up regulation of convergent extension involved in neural plate elongation|up-regulation of convergent extension involved in neural plate elongation|activation of convergent extension involved in neural plate elongation|upregulation of convergent extension involved in neural plate elongation							dph	2015-04-10T21:13:33Z					biological_process											owl:Class	
GO:0022007	biolink:NamedThing	convergent extension involved in neural plate elongation	The process of directed cell movement in the neural plate resulting in tissue elongation via intercalation of adjacent cells in an epithelial sheet at the midline, leading to narrowing and lengthening of the neural plate.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0021618	biolink:NamedThing	hypoglossal nerve morphogenesis	The process in which the anatomical structure of the hypoglossal nerve is generated and organized. This motor nerve innervates all the intrinsic and all but one of the extrinsic muscles of the tongue.	tmpzr1t_l9r_go_relaxed.owl	CN XII morphogenesis													biological_process											owl:Class	
GO:0021566	biolink:NamedThing	hypoglossal nerve development	The process whose specific outcome is the progression of the hypoglossal nerve over time, from its formation to the mature structure. This motor nerve innervates all the intrinsic and all but one of the extrinsic muscles of the tongue.	tmpzr1t_l9r_go_relaxed.owl	cranial nerve XII development|cranial nerve 12 development|CN XII development													biological_process											owl:Class	
GO:2000141	biolink:NamedThing	positive regulation of octopamine signaling pathway involved in response to food	Any process that activates or increases the frequency, rate or extent of octopamine signaling pathway involved in response to food.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of octopamine signalling pathway involved in response to food							mah	2010-09-30T02:48:12Z					biological_process											owl:Class	
GO:0010084	biolink:NamedThing	specification of animal organ axis polarity	The process in which the polarity of an animal organ axis is specified.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1902512	biolink:NamedThing	positive regulation of apoptotic DNA fragmentation	Any process that activates or increases the frequency, rate or extent of apoptotic DNA fragmentation.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of endonucleolytic DNA catabolic process involved in apoptosis|upregulation of endonucleolytic DNA catabolic process involved in apoptosis|upregulation of DNA catabolism during apoptosis|up regulation of apoptotic DNA fragmentation|up-regulation of DNA catabolic process during apoptosis|upregulation of DNA catabolic process during apoptosis|positive regulation of DNA fragmentation involved in apoptotic nuclear change|positive regulation of DNA catabolic process during apoptosis|up regulation of endonucleolytic DNA catabolic process involved in apoptosis|activation of endonucleolytic DNA catabolic process involved in apoptosis|upregulation of apoptotic DNA fragmentation|activation of DNA catabolism during apoptosis|up-regulation of DNA catabolism during apoptosis|activation of DNA catabolic process during apoptosis|up regulation of DNA catabolism during apoptosis|upregulation of DNA fragmentation involved in apoptotic nuclear change|up-regulation of apoptotic DNA fragmentation|up regulation of DNA catabolic process during apoptosis|up regulation of DNA fragmentation involved in apoptotic nuclear change|up-regulation of DNA fragmentation involved in apoptotic nuclear change|activation of DNA fragmentation involved in apoptotic nuclear change|positive regulation of DNA catabolism during apoptosis|activation of apoptotic DNA fragmentation|positive regulation of endonucleolytic DNA catabolic process involved in apoptosis							hjd	2013-11-15T18:28:50Z					biological_process											owl:Class	
GO:0006309	biolink:NamedThing	apoptotic DNA fragmentation	The cleavage of DNA during apoptosis, which usually occurs in two stages: cleavage into fragments of about 50 kbp followed by cleavage between nucleosomes to yield 200 bp fragments.	tmpzr1t_l9r_go_relaxed.owl	endonucleolytic DNA catabolic process involved in apoptosis|DNA catabolism during apoptosis|chromatinolysis|DNA fragmentation involved in apoptotic nuclear change|DNA fragmentation|DNA catabolic process during apoptosis					DNA fragmentation in response to apoptotic signals is achieved through the activity of apoptotic nucleases. In human, these include DNA fragmentation factor (DFF) or caspase-activated DNase (CAD) and endonuclease G (Endo G) (reviewed in PMID:15723341). Caution is needed when apoptotic DNA laddering assays show presence of fragmented DNA. A positive assay may simply reflect the end point of a whole apoptotic process. Unless clear experimental evidence is available to show that a gene product is directly involved in fragmenting DNA, please do not annotate to GO:0006309 'apoptotic DNA fragmentation' and consider annotating instead to a more upstream process such as, e.g., GO:0042981 'regulation of apoptotic process', GO:0006915 'apoptotic process', GO:0097190 'apoptotic signaling pathway'. Also, note that gene products involved in compartmentalization of apoptotic nucleases and in activation or repression of their enzymatic activity should be annotated to the regulation term GO:1902510 'regulation of apoptotic DNA fragmentation' or to one of its children (see PMID:15723341).						GO:0008178		biological_process											owl:Class	
GO:0031674	biolink:NamedThing	I band	A region of a sarcomere that appears as a light band on each side of the Z disc, comprising a region of the sarcomere where thin (actin) filaments are not overlapped by thick (myosin) filaments; contains actin, troponin, and tropomyosin; each sarcomere includes half of an I band at each end.	tmpzr1t_l9r_go_relaxed.owl	I disc|isotropic disc|J disc				Wikipedia:Sarcomere#bands									cellular_component											owl:Class	
GO:0030017	biolink:NamedThing	sarcomere	The repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Sarcomere									cellular_component											owl:Class	
GO:0005902	biolink:NamedThing	microvillus	Thin cylindrical membrane-covered projections on the surface of an animal cell containing a core bundle of actin filaments. Present in especially large numbers on the absorptive surface of intestinal cells.	tmpzr1t_l9r_go_relaxed.owl	microvilli				Wikipedia:Microvillus|NIF_Subcellular:sao671419673	Note that this term refers to a projection from a single cell, and should not be confused with 'microvillus' as used to refer to a multicellular structure such as that found in the placenta.								cellular_component											owl:Class	
GO:0099243	biolink:NamedThing	extrinsic component of synaptic membrane	The component of the synaptic membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.	tmpzr1t_l9r_go_relaxed.owl								dos	2017-05-25T17:24:23Z					cellular_component											owl:Class	
GO:1903853	biolink:NamedThing	regulation of stress response to copper ion	Any process that modulates the frequency, rate or extent of stress response to copper ion.	tmpzr1t_l9r_go_relaxed.owl	regulation of stress response to copper|regulation of response to copper toxicity|regulation of response to copper ion stress							kmv	2015-01-29T20:15:23Z					biological_process											owl:Class	
GO:0003253	biolink:NamedThing	cardiac neural crest cell migration involved in outflow tract morphogenesis	The orderly movement of a neural crest cell from one site to another that will contribute to the morphogenesis of the outflow tract.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-10-13T02:14:16Z					biological_process											owl:Class	
GO:0051838	biolink:NamedThing	cytolysis by host of symbiont cells	The killing by an organism of a cell in its symbiont organism by means of the rupture of cell membranes and the loss of cytoplasm. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0052337	biolink:NamedThing	modification by host of symbiont membrane	The process in which an organism effects a change in the structure or function of a symbiont cellular membrane. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	modification by host of symbiont cell membrane													biological_process											owl:Class	
GO:0008228	biolink:NamedThing	opsonization	The process in which a microorganism (or other particulate material) is rendered more susceptible to phagocytosis by coating with an opsonin, a blood serum protein such as a complement component or antibody.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Opsonin									biological_process											owl:Class	
GO:0045291	biolink:NamedThing	mRNA trans splicing, SL addition	The joining together of two independently transcribed RNAs, where the one that provides the 5' portion of the final mRNA is from a splice leader RNA (SL-RNA). The SL-RNA, or mini-exon donor sequence, is added to the 5'-end of the acceptor RNA molecule which provides the mRNA body.	tmpzr1t_l9r_go_relaxed.owl	nuclear mRNA trans splicing, spliced leader addition|nuclear mRNA trans splicing, SL addition													biological_process											owl:Class	
GO:0070304	biolink:NamedThing	positive regulation of stress-activated protein kinase signaling cascade	Any process that activates or increases the frequency, rate or extent of signaling via the stress-activated protein kinase signaling cascade.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of stress-activated protein kinase signaling pathway|activation of stress-activated protein kinase signaling pathway|up regulation of stress-activated protein kinase signaling pathway|positive regulation of SAPK signaling pathway|stimulation of stress-activated protein kinase signaling pathway|positive regulation of stress-activated protein kinase signalling pathway|upregulation of stress-activated protein kinase signaling pathway|positive regulation of stress-activated protein kinase signaling pathway													biological_process											owl:Class	
GO:0045263	biolink:NamedThing	proton-transporting ATP synthase complex, coupling factor F(o)	All non-F1 subunits of a hydrogen-transporting ATP synthase, including integral and peripheral membrane proteins.	tmpzr1t_l9r_go_relaxed.owl	hydrogen-transporting ATP synthase, F0 sector|hydrogen-transporting ATP synthase, coupling factor CF(0)|hydrogen-transporting ATP synthase complex, coupling factor F(o)|proton-transporting ATP synthase complex, coupling factor F(0)													cellular_component											owl:Class	
GO:2001091	biolink:NamedThing	nigerotriose transport	The directed movement of a nigerotrioseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl								jl	2011-09-21T01:51:49Z					biological_process											owl:Class	
GO:0071560	biolink:NamedThing	cellular response to transforming growth factor beta stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a transforming growth factor beta stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to TGFbeta stimulus|cellular response to TGF-beta stimulus							mah	2010-01-20T11:51:18Z					biological_process											owl:Class	
GO:0018991	biolink:NamedThing	oviposition	The deposition of eggs (either fertilized or not) upon a surface or into a medium such as water.	tmpzr1t_l9r_go_relaxed.owl	post-mating oviposition|egg laying|egg-laying				Wikipedia:Oviposition							GO:0060403		biological_process											owl:Class	
GO:1905255	biolink:NamedThing	regulation of RNA binding transcription factor activity	Any process that modulates the frequency, rate or extent of RNA binding transcription factor activity.	tmpzr1t_l9r_go_relaxed.owl	regulation of transcription factor activity							bf	2016-06-13T11:29:11Z					biological_process											owl:Class	
GO:0060634	biolink:NamedThing	regulation of 4,6-pyruvylated galactose residue biosynthetic process	Any process that modulates the rate, frequency, or extent of 4,6-pyruvylated galactose residue biosynthetic process, the chemical reactions and pathways resulting in the formation of the pyruvylated galactose residue 4-6-O-[(R)(1-carboxyethylidine)]-Gal-beta-(1->3)-. The galactose residue is part of a larger polysaccharide chain.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-05-18T03:15:39Z					biological_process											owl:Class	
GO:0051072	biolink:NamedThing	4,6-pyruvylated galactose residue biosynthetic process	The chemical reactions and pathways resulting in the formation of the pyruvylated galactose residue 4-6-O-[(R)(1-carboxyethylidine)]-Gal-beta-1,3-. The galactose residue is part of a larger polysaccharide chain.	tmpzr1t_l9r_go_relaxed.owl	PvGal biosynthesis|4,6-pyruvylated galactose residue formation|4,6-pyruvylated galactose residue synthesis|4-6-O-[(R)(1-carboxyethylidine)]-Gal-beta-1,3 biosynthesis|4,6-pyruvylated galactose residue biosynthesis|PvGal biosynthetic process|4,6-pyruvylated galactose residue anabolism|4-6-O-[(R)(1-carboxyethylidine)]-Gal-beta-1,3 biosynthetic process													biological_process											owl:Class	
GO:0017087	biolink:NamedThing	mitochondrial processing peptidase complex	A protein complex consisting of a regulatory subunit (alpha-MPP) and a catalytic subunit (beta-MPP) that catalyzes the release of N-terminal targeting peptides from precursor proteins imported into the mitochondrion.	tmpzr1t_l9r_go_relaxed.owl						Note that monomeric mitochondrial processing peptidases have been observed.								cellular_component											owl:Class	
GO:0038099	biolink:NamedThing	nodal receptor complex assembly	The aggregation, arrangement and bonding together of a set of components to form a complex containing a type II activin receptor, a type I activin receptor, and a coreceptor of the EGF-CFC family (e.g. Cripto or Cryptic, in mammals).	tmpzr1t_l9r_go_relaxed.owl	nodal receptor complex formation|ActRIIB.ALK4.EGF-CFC complex formation							bf	2012-02-17T11:16:40Z					biological_process											owl:Class	
GO:0048442	biolink:NamedThing	sepal development	The process whose specific outcome is the progression of the sepal over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl												GO:0048421		biological_process											owl:Class	
GO:1904046	biolink:NamedThing	negative regulation of vascular endothelial growth factor production	Any process that stops, prevents or reduces the frequency, rate or extent of vascular endothelial growth factor production.	tmpzr1t_l9r_go_relaxed.owl	down regulation of vascular endothelial growth factor production|down-regulation of vascular endothelial growth factor production|inhibition of VEGF production|downregulation of VEGF production|inhibition of vascular endothelial growth factor production|down-regulation of VEGF production|downregulation of vascular endothelial growth factor production|negative regulation of VEGF production|down regulation of VEGF production							sl	2015-03-16T23:27:06Z					biological_process											owl:Class	
GO:0010573	biolink:NamedThing	vascular endothelial growth factor production	The appearance of vascular endothelial growth factor production due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	tmpzr1t_l9r_go_relaxed.owl	VEGF production													biological_process											owl:Class	
GO:1900541	biolink:NamedThing	fumonisin biosynthetic process	The chemical reactions and pathways resulting in the formation of fumonisin.	tmpzr1t_l9r_go_relaxed.owl	fumonisin biosynthesis|fumonisin anabolism|fumonisin formation|fumonisin synthesis							tb	2012-05-11T12:54:37Z					biological_process											owl:Class	
GO:0002549	biolink:NamedThing	negative regulation of plasma kallikrein-kinin cascade	Any process that stops, prevents, or reduces the frequency, rate, or extent of the plasma kallikrein-kinin cascade.	tmpzr1t_l9r_go_relaxed.owl	down regulation of plasma kallikrein-kinin cascade|down-regulation of plasma kallikrein-kinin cascade|inhibition of plasma kallikrein-kinin cascade|downregulation of plasma kallikrein-kinin cascade													biological_process											owl:Class	
GO:0001544	biolink:NamedThing	initiation of primordial ovarian follicle growth	Increase in size of primordial follicles including proliferation and shape changes of granulosa and/or theca cells until oocyte is surrounded by one layer of cuboidal shaped granulosa cells (primary follicle).	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0035817	biolink:NamedThing	renal sodium ion absorption involved in negative regulation of renal sodium excretion	Any process where sodium ions are taken up from the collecting ducts and proximal and distal loops of the nephron, which contributes to decreasing the amount of sodium that is excreted in urine per unit time.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-04-20T01:40:11Z					biological_process											owl:Class	
GO:1904255	biolink:NamedThing	negative regulation of iron ion transmembrane transporter activity	Any process that stops, prevents or reduces the frequency, rate or extent of an iron transmembrane transporter activity.	tmpzr1t_l9r_go_relaxed.owl	down regulation of iron cation channel activity|negative regulation of iron-specific channel activity|down regulation of iron-specific channel activity|negative regulation of iron channel activity|down-regulation of iron channel activity|downregulation of iron channel activity|inhibition of iron cation channel activity|inhibition of iron channel activity|down-regulation of iron-specific channel activity|negative regulation of iron cation channel activity|downregulation of iron cation channel activity|down-regulation of iron cation channel activity|down regulation of iron channel activity|inhibition of iron-specific channel activity|downregulation of iron-specific channel activity							kom	2015-05-20T14:05:06Z					biological_process											owl:Class	
GO:0097581	biolink:NamedThing	lamellipodium organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lamellipodium. A lamellipodium is a thin sheetlike process extended by the leading edge of a crawling fibroblast; contains a dense meshwork of actin filaments.	tmpzr1t_l9r_go_relaxed.owl								pr	2014-02-28T16:08:56Z					biological_process											owl:Class	
GO:0045284	biolink:NamedThing	plasma membrane fumarate reductase complex	A membrane-bound flavoenzyme complex consisting of four subunits, A, B, C, and D. A and B comprise the membrane-extrinsic catalytic domain and C (InterPro:IPR003510; InterPro:IPR00224) and D (InterPro:IPR003418) link the catalytic centers to the electron-transport chain. In some species, the complex has only three subunits, and in these cases, there is only one membrane anchor instead of two. This family consists of the 13 kDa hydrophobic subunit D. This component may be required to anchor the catalytic components of the fumarate reductase complex to the cytoplasmic membrane. Fumarate reductase couples the reduction of fumarate to succinate to the oxidation of quinol to quinone, in a reaction opposite to that catalyzed by the related complex II of the respiratory chain (succinate dehydrogenase-(ubiquinone)). Examples of this component are found in bacterial species.	tmpzr1t_l9r_go_relaxed.owl	fumarate reductase complex					See also the molecular function term 'succinate dehydrogenase (ubiquinone) activity ; GO:0008177'.								cellular_component											owl:Class	
GO:0045179	biolink:NamedThing	apical cortex	The region that lies just beneath the plasma membrane on the apical edge of a cell.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0072567	biolink:NamedThing	chemokine (C-X-C motif) ligand 2 production	The appearance of chemokine (C-X-C motif) ligand 2 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	tmpzr1t_l9r_go_relaxed.owl	MIP-2 production|SCYB2 production|MIP2 production|CXCL2 production							mah	2011-01-31T11:33:40Z					biological_process											owl:Class	
GO:0016068	biolink:NamedThing	type I hypersensitivity	An inflammatory response driven by antigen recognition by antibodies bound to Fc receptors on mast cells or basophils, occurring within minutes after exposure of a sensitized individual to the antigen, and leading to the release of a variety of inflammatory mediators such as histamines.	tmpzr1t_l9r_go_relaxed.owl	immediate hypersensitivity response				Wikipedia:Type_I_hypersensitivity	Note that localized and systemic anaphylaxis is usually a result of type I hypersensitivity.								biological_process											owl:Class	
GO:0032105	biolink:NamedThing	negative regulation of response to extracellular stimulus	Any process that stops, prevents, or reduces the frequency, rate or extent of a response to an extracellular stimulus.	tmpzr1t_l9r_go_relaxed.owl	down regulation of response to extracellular stimulus|down-regulation of response to extracellular stimulus|inhibition of response to extracellular stimulus|downregulation of response to extracellular stimulus													biological_process											owl:Class	
GO:0010097	biolink:NamedThing	specification of stamen identity	The process in which a floral organ primordium acquires stamen or staminode identity. Identity is considered to be the aggregate of characteristics by which a structure is recognized.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0048455	biolink:NamedThing	stamen formation	The process that contributes to the act of giving rise to the stamen. This process pertains to the initial formation of a structure from unspecified parts.	tmpzr1t_l9r_go_relaxed.owl												GO:0048427		biological_process											owl:Class	
GO:0045214	biolink:NamedThing	sarcomere organization	The myofibril assembly process that results in the organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs.	tmpzr1t_l9r_go_relaxed.owl	sarcomere organisation|sarcomere alignment											GO:0006938		biological_process											owl:Class	
GO:0048085	biolink:NamedThing	adult chitin-containing cuticle pigmentation	Establishment of the adult pattern of pigmentation in the chitin-containing cuticle of an organism. An example of this is the adult cuticle pigmentation process in Drosophila melanogaster.	tmpzr1t_l9r_go_relaxed.owl	adult cuticle pigmentation											GO:0048068		biological_process											owl:Class	
GO:0035992	biolink:NamedThing	tendon formation	The process that gives rise to a tendon. This process pertains to the initial formation of a tendon from unspecified parts.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-08-30T01:35:10Z					biological_process											owl:Class	
GO:0048716	biolink:NamedThing	labrum morphogenesis	The process in which the anatomical structures of labrum are generated and organized.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0030129	biolink:NamedThing	clathrin coat of synaptic vesicle	A clathrin coat found on a synaptic vesicle.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0021663	biolink:NamedThing	rhombomere 4 formation	The process that gives rise to rhombomere 4. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0038202	biolink:NamedThing	TORC1 signaling	A series of intracellular molecular signals mediated by TORC1; TOR (target of rapamycin) in complex with at least Raptor (regulatory-associated protein of TOR), or orthologs of, and other signaling components.	tmpzr1t_l9r_go_relaxed.owl	TORC1 signal transduction							bf	2013-12-09T14:43:29Z					biological_process											owl:Class	
GO:0036124	biolink:NamedThing	histone H3-K9 trimethylation	The modification of histone H3 by addition of three methyl groups to lysine at position 9 of the histone.	tmpzr1t_l9r_go_relaxed.owl								bf	2012-02-20T03:08:06Z					biological_process											owl:Class	
GO:0000302	biolink:NamedThing	response to reactive oxygen species	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reactive oxygen species stimulus. Reactive oxygen species include singlet oxygen, superoxide, and oxygen free radicals.	tmpzr1t_l9r_go_relaxed.owl	response to AOS|response to reactive oxygen intermediate|response to ROI|response to active oxygen species|response to reactive oxidative species|response to ROS													biological_process											owl:Class	
GO:0140220	biolink:NamedThing	pathogen-containing vacuole	A membrane-bound intracellular compartment that is formed upon internalization of a pathogen into a host cell, and in which the pathogen resides.	tmpzr1t_l9r_go_relaxed.owl	pathogen-containing compartment|pathogen inclusion	https://github.com/geneontology/go-ontology/issues/15580						pg	2018-04-20T06:02:14Z					cellular_component											owl:Class	
GO:0004055	biolink:NamedThing	argininosuccinate synthase activity	Catalysis of the reaction: ATP + L-citrulline + L-aspartate = AMP + diphosphate + (N(omega)-L-arginino)succinate.	tmpzr1t_l9r_go_relaxed.owl	argininosuccinate synthetase activity|arginosuccinate synthetase activity|L-citrulline:L-aspartate ligase (AMP-forming)|argininosuccinic acid synthetase activity|citrulline--aspartate ligase activity|arginine succinate synthetase activity				Reactome:R-HSA-70577|EC:6.3.4.5|MetaCyc:ARGSUCCINSYN-RXN|RHEA:10932									molecular_function											owl:Class	
GO:1902476	biolink:NamedThing	chloride transmembrane transport	The process in which chloride is transported across a membrane.	tmpzr1t_l9r_go_relaxed.owl								bf	2013-10-28T09:44:29Z					biological_process											owl:Class	
GO:0032205	biolink:NamedThing	negative regulation of telomere maintenance	Any process that stops, prevents, or reduces the frequency, rate or extent of a process that affects and monitors the activity of telomeric proteins and the length of telomeric DNA.	tmpzr1t_l9r_go_relaxed.owl	inhibition of telomere maintenance|down-regulation of telomere maintenance|down regulation of telomere maintenance|downregulation of telomere maintenance													biological_process											owl:Class	
GO:0005967	biolink:NamedThing	mitochondrial pyruvate dehydrogenase complex	Complex that carries out the oxidative decarboxylation of pyruvate to form acetyl-CoA in eukaryotes; includes subunits possessing three catalytic activities: pyruvate dehydrogenase (E1), dihydrolipoamide S-acetyltransferase (E2), and dihydrolipoamide dehydrogenase (E3). The This Eukaryotic form usually contains more subunits than its bacterial counterpart; for example, one known complex contains 30 E1 dimers, 60 E2 monomers, and 6 E3 dimers as well as a few copies of pyruvate dehydrogenase kinase and pyruvate dehydrogenase phosphatase.	tmpzr1t_l9r_go_relaxed.owl	pyruvate dehydrogenase complex (lipoamide)					Note that this term represents a location and not a function; the activity possessed by this complex is mentioned in the definition for the purpose of describing and distinguishing the complex. The functions of this complex are represented by the molecular function terms 'pyruvate dehydrogenase (lipoamide) activity ; GO:0004739', 'dihydrolipoamide S-acetyltransferase activity ; GO:0004742', and 'dihydrolipoamide dehydrogenase activity ; GO:0004148'.								cellular_component											owl:Class	
GO:0010644	biolink:NamedThing	cell communication by electrical coupling	The process that mediates signaling interactions between one cell and another cell by transfer of current between their adjacent cytoplasms via intercellular protein channels.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1904370	biolink:NamedThing	regulation of protein localization to actin cortical patch	Any process that modulates the frequency, rate or extent of protein localization to actin cortical patch.	tmpzr1t_l9r_go_relaxed.owl	regulation of protein localisation to actin cortical patch							sl	2015-06-18T22:23:31Z					biological_process											owl:Class	
GO:0099534	biolink:NamedThing	calcium ion binding involved in regulation of presynaptic cytosolic calcium ion concentration	The directed change of presynaptic cytosolic free calcium ion concentration in the cytosol via the reversible binding of calcium ions to calcium-binding proteins in the cytosol thereby modulating the spatial and temporal dynamics of changes in presynaptic cytosolic calcium concentrations.	tmpzr1t_l9r_go_relaxed.owl	presynaptic calcium ion buffering|calcium ion binding involved in regulation of presynaptic cytosolic calcium levels|regulation of presynaptic cytosolic calcium ion concentration by calcium ion buffering													molecular_function											owl:Class	
GO:0070685	biolink:NamedThing	macropinocytic cup	A cell projection that forms at the site of macropinocytosis, a form of endocytosis that results in the uptake of relatively large amounts of extracellular fluid. The macropinocytic cup membrane selectively excludes certain proteins, such as H36 or PM4C4 in Dictyostelium, and the underlying cytoskeleton is enriched in F-actin and coronin.	tmpzr1t_l9r_go_relaxed.owl	crown							mah	2009-06-03T10:18:00Z					cellular_component											owl:Class	
GO:0042645	biolink:NamedThing	mitochondrial nucleoid	The region of a mitochondrion to which the DNA is confined.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0008200	biolink:NamedThing	ion channel inhibitor activity	Binds to and stops, prevents, or reduces the activity of an ion channel.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0070254	biolink:NamedThing	mucus secretion	The regulated release of mucus by the mucosa. Mucus is a viscous slimy secretion consisting of mucins and various inorganic salts dissolved in water, with suspended epithelial cells and leukocytes. The mucosa, or mucous membrane, is the membrane covered with epithelium that lines the tubular organs of the body. Mucins are carbohydrate-rich glycoproteins that have a lubricating and protective function.	tmpzr1t_l9r_go_relaxed.owl	mucus production													biological_process											owl:Class	
GO:1901589	biolink:NamedThing	axon microtubule bundle	An arrangement of closely apposed microtubules running parallel to each other in the axon hillock and initial segment.	tmpzr1t_l9r_go_relaxed.owl	axon microtubule fascicle|microtubule fascicle of axon|microtubule bundle of axon				NIF_Subcellular:sao707332678			pr	2012-11-07T15:37:12Z					cellular_component											owl:Class	
GO:0002572	biolink:NamedThing	pro-T cell differentiation	The process in which a precursor cell type acquires the specialized features of a pro-T cell. Pro-T cells are the earliest stage of the T cell lineage but are not fully committed.	tmpzr1t_l9r_go_relaxed.owl	pro-T lymphocyte differentiation													biological_process											owl:Class	
GO:0035930	biolink:NamedThing	corticosteroid hormone secretion	The regulated release of any corticosteroid hormone into the circulatory system.	tmpzr1t_l9r_go_relaxed.owl	corticosteroid secretion							bf	2011-07-20T01:03:22Z					biological_process											owl:Class	
GO:0043679	biolink:NamedThing	axon terminus	Terminal inflated portion of the axon, containing the specialized apparatus necessary to release neurotransmitters. The axon terminus is considered to be the whole region of thickening and the terminal button is a specialized region of it.	tmpzr1t_l9r_go_relaxed.owl	nerve ending|axon terminal specialization|axon terminal				NIF_Subcellular:nlx_subcell_20090512									cellular_component											owl:Class	
GO:0061697	biolink:NamedThing	protein-glutaryllysine deglutarylase activity	Catalysis of the reaction: H2O + N(6)-glutaryl-L-lysyl-[protein] + NAD(+) = 2''-O-glutaryl-ADP-D-ribose + L-lysyl-[protein] + nicotinamide.	tmpzr1t_l9r_go_relaxed.owl					RHEA:47664	This reaction is the removal of a glutaryl group from a glutarylated lysine residue of a protein or peptide.		dph	2015-05-07T10:55:53Z					molecular_function											owl:Class	
GO:0061699	biolink:NamedThing	peptidyl-lysine deglutarylation	The removal of a glutaryl group (CO-CH2-CH2--CH2-CO) from a glutarylated lysine residue in a peptide or protein.	tmpzr1t_l9r_go_relaxed.owl								dph	2015-05-07T11:04:42Z					biological_process											owl:Class	
GO:0043597	biolink:NamedThing	cytoplasmic replication fork	The Y-shaped region of a cytoplasmic replicating DNA molecule, resulting from the separation of the DNA strands and in which the synthesis of new strands takes place. Also includes associated protein complexes.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0014020	biolink:NamedThing	primary neural tube formation	The formation of the neural tube from an epithelial cell sheet (the neuroepithelium or neural plate). In primary neurulation, the cells surrounding the neural plate direct the neural plate cells to proliferate, invaginate, and pinch off from the surface to form a hollow epithelial tube. Primary neurulation is the typical mechanism of formation of the anterior neural tube.	tmpzr1t_l9r_go_relaxed.owl	primary neurulation|primary neural tube morphogenesis													biological_process											owl:Class	
GO:0060032	biolink:NamedThing	notochord regression	The developmental process in which the stucture of the notochord is destroyed in an embryo.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0048570	biolink:NamedThing	notochord morphogenesis	The process in which the anatomical structures of the notochord are generated and organized. The notochord is a mesoderm-derived structure located ventral of the developing nerve cord. In vertebrates, the notochord serves as a core around which other mesodermal cells form the vertebrae. In the most primitive chordates, which lack vertebrae, the notochord persists as a substitute for a vertebral column.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0010857	biolink:NamedThing	calcium-dependent protein kinase activity	Calcium-dependent catalysis of the reaction: a protein + ATP = a phosphoprotein + ADP.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-8986937|Reactome:R-HSA-9005561	This reaction requires the presence of calcium.								molecular_function											owl:Class	
GO:0021532	biolink:NamedThing	neural tube patterning	The regionalization process that regulates the coordinated growth that establishes the non-random spatial arrangement of the neural tube.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0021915	biolink:NamedThing	neural tube development	The process whose specific outcome is the progression of the neural tube over time, from its formation to the mature structure. The mature structure of the neural tube exists when the tube has been segmented into the forebrain, midbrain, hindbrain and spinal cord regions. In addition neural crest has budded away from the epithelium.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0009574	biolink:NamedThing	preprophase band	A dense band of microtubules, 1-3 pm wide, that appears just beneath the cell membrane before the start of cell division in the cells of higher plants. It precedes the onset of prophase and then disappears as mitosis begins, yet it somehow determines the plane of orientation of the new cell plate forming in late telophase and marks the zone of the parental cell wall where fusion with the growing cell plate ultimately occurs.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Preprophase_band									cellular_component											owl:Class	
GO:0010797	biolink:NamedThing	regulation of multivesicular body size involved in endosome transport	Any process that modulates the volume of a multivesicular body as part of the directed movement of substances from endosomes to lysosomes or vacuoles.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0009360	biolink:NamedThing	DNA polymerase III complex	The DNA polymerase III holoenzyme is a complex that contains 10 different types of subunits. These subunits are organized into 3 functionally essential sub-assemblies: the pol III core, the beta sliding clamp processivity factor and the clamp-loading complex. The pol III core carries out the polymerase and the 3'-5' exonuclease proofreading activities. The polymerase is tethered to the template via the sliding clamp processivity factor. The clamp-loading complex assembles the beta processivity factor onto the primer template and plays a central role in the organization and communication at the replication fork.	tmpzr1t_l9r_go_relaxed.owl	DNA polymerase III holoenzyme complex													cellular_component											owl:Class	
GO:0010778	biolink:NamedThing	meiotic DNA repair synthesis involved in reciprocal meiotic recombination	The synthesis of DNA proceeding from the broken 3' single-strand DNA end that uses the homologous intact duplex as the template resulting in meiotic recombination. Meiotic recombination is the cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0071142	biolink:NamedThing	homomeric SMAD protein complex	A protein complex composed of a single type of SMAD family proteins. In the absence of Smad4, phosphorylation of R-SMADs results in their homotrimerization. However, these complexes do not appear to import into the nucleus and are assumed to be transcriptionally inactive.	tmpzr1t_l9r_go_relaxed.owl	SMAD3 homotrimer complex|SMAD2 protein complex|SMAD1 protein complex|SMAD3 protein complex|SMAD1 homotrimer complex|SMAD2 homotrimer complex							mah	2009-11-16T02:41:19Z			GO:0071143		cellular_component											owl:Class	
GO:1902686	biolink:NamedThing	mitochondrial outer membrane permeabilization involved in programmed cell death	The process by which the mitochondrial outer membrane becomes permeable to the passing of proteins and other molecules from the intermembrane space to the cytosol as part of a programmed cell death process.	tmpzr1t_l9r_go_relaxed.owl	mitochondrial membrane permeability transition involved in regulated cell death|MPT involved in programmed cell death|mitochondrial membrane permeabilization involved in caspase-independent cell death|mitochondrial membrane permeability transition involved in PCD|mitochondrial permeability transition involved in programmed cell death|MPT involved in caspase-independent apoptosis|mitochondrion outer membrane permeabilization involved in programmed cell death|MPT involved in caspase-independent cell death|positive regulation of transport across mitochondrial membrane involved in caspase-independent apoptosis|mitochondrial permeability transition involved in regulated cell death|mitochondrial outer membrane permeabilization during programmed cell death|mitochondrial membrane permeabilization involved in regulated cell death|positive regulation of mitochondrial membrane permeability involved in programmed cell death|mitochondrial membrane permeability transition involved in programmed cell death|MPT involved in PCD|mitochondrial membrane permeability transition involved in caspase-independent cell death|mitochondrial membrane permeabilization involved in caspase-independent apoptosis|mitochondrial membrane permeabilization involved in non-apoptotic programmed cell death|MPT involved in nonapoptotic programmed cell death|mitochondrial permeability transition involved in PCD|positive regulation of mitochondrial membrane permeability involved in non-apoptotic programmed cell death|MPT involved in regulated cell death|mitochondrial membrane permeabilization involved in PCD|positive regulation of transport across mitochondrial membrane involved in programmed cell death|mitochondrial permeability transition involved in caspase-independent apoptosis|mitochondrial permeability transition involved in caspase-independent cell death|mitochondrial permeability transition involved in nonapoptotic programmed cell death|mitochondrial membrane permeability transition involved in nonapoptotic programmed cell death|MPT involved in non-apoptotic programmed cell death|positive regulation of transport across mitochondrial membrane involved in nonapoptotic programmed cell death|positive regulation of mitochondrial membrane permeability involved in caspase-independent apoptosis|positive regulation of mitochondrial membrane permeability involved in caspase-independent cell death|mitochondrial membrane permeability transition involved in non-apoptotic programmed cell death|mitochondrial permeability transition involved in non-apoptotic programmed cell death|positive regulation of transport across mitochondrial membrane involved in non-apoptotic programmed cell death|positive regulation of transport across mitochondrial membrane involved in regulated cell death|positive regulation of mitochondrial membrane permeability involved in PCD|positive regulation of transport across mitochondrial membrane involved in caspase-independent cell death|mitochondrial membrane permeabilization involved in nonapoptotic programmed cell death|positive regulation of transport across mitochondrial membrane involved in PCD|positive regulation of mitochondrial membrane permeability involved in regulated cell death|mitochondrial membrane permeability transition involved in caspase-independent apoptosis|positive regulation of mitochondrial membrane permeability involved in nonapoptotic programmed cell death|mitochondrial membrane permeabilization involved in programmed cell death							pr	2014-02-10T12:56:34Z					biological_process											owl:Class	
GO:0060624	biolink:NamedThing	regulation of ascospore wall (1->3)-beta-D-glucan biosynthetic process	Any process that modulates the rate, frequency, or extent of ascospore wall (1->3)-beta-D-glucan biosynthetic process, the chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D--glucosidic bonds, found in the walls of ascospores.	tmpzr1t_l9r_go_relaxed.owl	regulation of ascospore wall 1,3-beta-glucan biosynthetic process|regulation of ascospore wall 1,3-beta-D-glucan biosynthetic process							dph	2009-05-18T02:18:10Z					biological_process											owl:Class	
GO:0051620	biolink:NamedThing	norepinephrine uptake	The directed movement of norepinephrine into a cell, typically presynaptic neurons or glial cells. Norepinephrine (3,4-dihydroxyphenyl-2-aminoethanol) is a hormone secreted by the adrenal medulla and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts of the CNS. It is also the biosynthetic precursor of epinephrine.	tmpzr1t_l9r_go_relaxed.owl	norepinephrine import|levarterenol uptake|noradrenaline uptake|noradrenaline reuptake|norepinephrine reuptake|levarterenol reuptake													biological_process											owl:Class	
GO:0070043	biolink:NamedThing	rRNA (guanine-N7-)-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing N7-methylguanine.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-6790982									molecular_function											owl:Class	
GO:0070476	biolink:NamedThing	rRNA (guanine-N7)-methylation	The addition of a methyl group to the N7 atom in the base portion of a guanine nucleotide residue in an rRNA molecule.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0140620	biolink:NamedThing	DNA strand exchange inhibitor activity	Binds to and stops, prevents or reduces a DNA strand exchange activity.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/20964						pg	2021-02-26T17:57:00Z					molecular_function											owl:Class	
GO:0000150	biolink:NamedThing	DNA strand exchange activity	Catalysis of the identification and base-pairing of homologous sequences between single-stranded DNA and double-stranded DNA.	tmpzr1t_l9r_go_relaxed.owl	strand exchange activity|recombinase activity|RecA-family recombinase activity|strand transferase	https://github.com/geneontology/go-ontology/issues/20964			Reactome:R-HSA-912458	Note that this term represents activities that do not break or form phosphodiester bonds, and is therefore not a parent of 'site-specific recombinase activity ; GO:0009009'.								molecular_function											owl:Class	
GO:1904280	biolink:NamedThing	negative regulation of transcription by RNA polymerase V	Any process that stops, prevents or reduces the frequency, rate or extent of transcription mediated by RNA polymerase V.	tmpzr1t_l9r_go_relaxed.owl	downregulation of transcription from RNA pol V promoter|negative regulation of transcription from RNA polymerase V promoter|down-regulation of transcription from RNA polymerase V promoter|down regulation of transcription from RNA polymerase V promoter|negative regulation of transcription from RNA pol V promoter|downregulation of transcription from RNA polymerase V promoter|down regulation of transcription from RNA pol V promoter|inhibition of transcription from RNA polymerase V promoter|inhibition of transcription from RNA pol V promoter|down-regulation of transcription from RNA pol V promoter							tb	2015-06-03T22:01:54Z					biological_process											owl:Class	
GO:0001055	biolink:NamedThing	RNA polymerase II activity	Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template that contains an RNA polymerase II specific promoter to direct initiation and catalyses DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'.	tmpzr1t_l9r_go_relaxed.owl	DNA-directed RNA polymerase activity involved in transcription from RNA polymerase II promoter				Reactome:R-HSA-6814559|Reactome:R-HSA-6814549			krc	2010-09-23T03:44:23Z					molecular_function											owl:Class	
GO:0021706	biolink:NamedThing	locus ceruleus maturation	A developmental process, independent of morphogenetic (shape) change, that is required for the locus ceruleus to attain its fully functional state. The locus ceruleus is a dense cluster of neurons within the dorsorostral pons. This nucleus is the major location of neurons that release norepinephrine throughout the brain, and is responsible for physiological responses to stress and panic.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0021586	biolink:NamedThing	pons maturation	A developmental process, independent of morphogenetic (shape) change, that is required for the pons to attain its fully functional state. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0033091	biolink:NamedThing	positive regulation of immature T cell proliferation	Any process that activates or increases the frequency, rate or extent of immature T cell proliferation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0007339	biolink:NamedThing	binding of sperm to zona pellucida	The process in which the sperm binds to the zona pellucida glycoprotein layer of the egg. The process begins with the attachment of the sperm plasma membrane to the zona pellucida and includes attachment of the acrosome inner membrane to the zona pellucida after the acrosomal reaction takes place.	tmpzr1t_l9r_go_relaxed.owl	ZPG binding													biological_process											owl:Class	
GO:1901329	biolink:NamedThing	regulation of odontoblast differentiation	Any process that modulates the frequency, rate or extent of odontoblast differentiation.	tmpzr1t_l9r_go_relaxed.owl								hjd	2012-08-31T16:50:05Z					biological_process											owl:Class	
GO:0061271	biolink:NamedThing	mesenchymal to epithelial transition involved in mesonephric renal vesicle formation	A transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the mesonephric renal vesicle.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-08-30T03:26:30Z					biological_process											owl:Class	
GO:1900318	biolink:NamedThing	regulation of methane biosynthetic process from dimethylamine	Any process that modulates the frequency, rate or extent of methane biosynthetic process from dimethylamine.	tmpzr1t_l9r_go_relaxed.owl								tt	2012-04-06T01:43:21Z					biological_process											owl:Class	
GO:0033618	biolink:NamedThing	plasma membrane respiratory chain complex IV assembly	The aggregation, arrangement and bonding together of a set of components to form respiratory chain complex IV (also known as cytochrome c oxidase) in the plasma membrane.	tmpzr1t_l9r_go_relaxed.owl	plasma membrane cytochrome c oxidase biogenesis|plasma membrane cytochrome c oxidase complex assembly													biological_process											owl:Class	
GO:0061450	biolink:NamedThing	trophoblast cell migration	Trophoblast cell migration that is accomplished by extension and retraction of a pseudopodium. Trophoblast cells line the outside of the blastocyst.	tmpzr1t_l9r_go_relaxed.owl								dph	2012-07-10T08:38:37Z					biological_process											owl:Class	
GO:0021907	biolink:NamedThing	fibroblast growth factor receptor signaling pathway involved in spinal cord anterior/posterior pattern formation	The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands that results in the spatial identity of regions along the anterior-posterior axis of the spinal cord.	tmpzr1t_l9r_go_relaxed.owl	fibroblast growth factor receptor signalling pathway in spinal cord anterior-posterior patterning													biological_process											owl:Class	
GO:0036162	biolink:NamedThing	oxytocin production	The appearance of oxytocin, a cyclic nonapeptide hormone with amino acid sequence CYIQNCPLG, due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Oxytocin is the principal uterine-contracting and milk-ejecting hormone of the posterior pituitary, and together with the neuropeptide vasopressin, is believed to influence social cognition and behavior. It also acts as a neurotransmitter in the brain.	tmpzr1t_l9r_go_relaxed.owl	oxytocin biosynthesis|oxytocin secretion	https://github.com/geneontology/go-ontology/issues/21535|https://github.com/geneontology/go-ontology/issues/9542				Note that this term is intended for use when a gene product is seen to cause apparent increases in intracellular or extracellular oxytocin levels, without specific regard as to whether the increase is due to increased biosynthesis, increased secretion of preexisting oxytocin molecules, or increased conversion from precursor molecules.		bf	2012-03-26T01:43:46Z					biological_process											owl:Class	
GO:2001150	biolink:NamedThing	positive regulation of dipeptide transmembrane transport	Any process that activates or increases the frequency, rate or extent of dipeptide transmembrane transport.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of dipeptide membrane transport							kmv	2011-10-21T06:10:03Z					biological_process											owl:Class	
GO:0007422	biolink:NamedThing	peripheral nervous system development	The process whose specific outcome is the progression of the peripheral nervous system over time, from its formation to the mature structure. The peripheral nervous system is one of the two major divisions of the nervous system. Nerves in the PNS connect the central nervous system (CNS) with sensory organs, other organs, muscles, blood vessels and glands.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0060673	biolink:NamedThing	cell-cell signaling involved in placenta development	Any process that mediates the transfer of information from one cell to another.	tmpzr1t_l9r_go_relaxed.owl	cell-cell signalling involved in placenta development							dph	2009-06-02T12:58:03Z					biological_process											owl:Class	
GO:0000386	biolink:NamedThing	second spliceosomal transesterification activity	Catalysis of the second transesterification reaction of spliceosomal mRNA splicing. Ligation of the two exons occurs via a transesterification reaction where the free 3'-hydroxyl group of the 5' exon is the nucleophile attacking the 3' splice site. Non-expressed sequences are now detached from the exons. In cis splicing, the intron is in a lariat structure.	tmpzr1t_l9r_go_relaxed.owl	3'-splice site cleavage, exon ligation|lariat formation, 5'-splice site cleavage													molecular_function											owl:Class	
GO:0033099	biolink:NamedThing	attachment organelle	A membrane-bounded extension of the cell, originally characterized in Mycoplasma species, that contains an electron-dense core that is part of the cytoskeleton and is oriented lengthwise and ends distally in a bulbous knob (terminal button). Required for adherence to host cells and involved in gliding motility and cell division.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0097564	biolink:NamedThing	right lateral basal body pair	Set of two basal bodies found in Giardia species (trophozoite stage). It comprises the anterior and ventral basal bodies located to the left of the right nucleus of the trophozoite when viewed dorsally.	tmpzr1t_l9r_go_relaxed.owl						Due to the asymmetric nature of the Giardia trophozoite, this term is defined spatially as the trophozoite is viewed from the dorsal side, with the two nuclei dorsal to the ventral disc, and the ventral disc toward the anterior.		pr	2014-02-05T16:12:42Z					cellular_component											owl:Class	
GO:0000477	biolink:NamedThing	generation of mature 5'-end of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	Cleavage within ITS2 to generate the mature 5'-end of an LSU-rRNA derived from a tricistronic rRNA transcript that contained the Small SubUnit (SSU) rRNA, the 5.8S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript.	tmpzr1t_l9r_go_relaxed.owl	processing at C1													biological_process											owl:Class	
GO:1990499	biolink:NamedThing	raps-insc complex	Protein complex required for the asymmetric division of neuroblasts in Drosophila. Coordinates asymmetric localization of cell fate determinants with orientation of the mitotic spindle resulting in different daughter cells upon division. Localizes at the apical cortex of the neuroblast: Raps maintains, but does not initiate, Insc apically, while Insc segregates Raps asymmetrically. Complex appears to be conserved in mammals (composed of INSC and GPSM1 or GPSM2).	tmpzr1t_l9r_go_relaxed.owl	partner of inscuteable-inscuteable complex|Rapsynoid-Inscuteable complex					An example of this is Insc in drome (Q9W2R4) in PMID:22171003 (inferred from physical interaction).		bhm	2014-09-30T09:22:18Z					cellular_component											owl:Class	
GO:1904600	biolink:NamedThing	actin fusion focus assembly	The aggregation, arrangement and bonding together of a set of components to form an actin fusion focus.	tmpzr1t_l9r_go_relaxed.owl	actin fusion focus formation	https://github.com/geneontology/go-ontology/issues/21688						al	2015-08-26T10:34:48Z					biological_process											owl:Class	
GO:0072127	biolink:NamedThing	renal capsule development	The process whose specific outcome is the progression of the renal capsule over time, from its formation to the mature structure. The renal capsule is the tough fibrous layer surrounding the kidney, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage. During development, it comprises a single layer of flattened cells that lie just above the cortical stroma and the condensed mesenchyme of the nephrogenic zone. It is in this region that the early stages of nephron induction and formation of new generations ureteric bud branches occur, as the kidney expands.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-02-22T02:02:55Z					biological_process											owl:Class	
GO:1990230	biolink:NamedThing	iron-sulfur cluster transfer complex	A protein complex capable of catalyzing the transfer of an iron-sulfur (Fe-S) cluster from one compound (donor) to another (acceptor).	tmpzr1t_l9r_go_relaxed.owl	IscA complex|Fe-S cluster transfer complex|SufA complex|SufA dimer							bhm	2013-11-12T09:17:40Z					cellular_component											owl:Class	
GO:1900420	biolink:NamedThing	negative regulation of cellular alcohol catabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of cellular alcohol catabolic process.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of cellular alcohol catabolic process|down regulation of cellular alcohol catabolic process|downregulation of cellular alcohol catabolic process|inhibition of cellular alcohol catabolic process							krc	2012-04-20T10:21:28Z					biological_process											owl:Class	
GO:0035480	biolink:NamedThing	regulation of Notch signaling pathway involved in heart induction	Any process that modulates the frequency, rate or extent of the series of molecular signals initiated by binding of an extracellular ligand to a Notch receptor on the surface of the target cell that contributes to heart induction.	tmpzr1t_l9r_go_relaxed.owl	regulation of Notch signalling pathway involved in heart induction							bf	2010-04-23T10:40:48Z					biological_process											owl:Class	
GO:0003137	biolink:NamedThing	Notch signaling pathway involved in heart induction	The series of molecular signals initiated by binding of an extracellular ligand to a Notch receptor on the surface of the target cell that contributes to heart induction.	tmpzr1t_l9r_go_relaxed.owl	Notch signalling pathway involved in heart induction							tb	2009-09-22T03:28:42Z					biological_process											owl:Class	
GO:0070377	biolink:NamedThing	negative regulation of ERK5 cascade	Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the ERK5 cascade.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of BMK signaling pathway|down regulation of BMK cascade|down-regulation of BMK cascade|negative regulation of BMK cascade|negative regulation of BMK signalling pathway|negative regulation of ERK5 signaling pathway|negative regulation of BMK1 cascade|downregulation of BMK cascade|negative regulation of MAPK7 cascade|inhibition of BMK cascade													biological_process											owl:Class	
GO:1902646	biolink:NamedThing	regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process	Any process that modulates the frequency, rate or extent of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate formation|regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate synthesis|regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate anabolism|regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthesis							di	2014-01-21T17:57:57Z					biological_process											owl:Class	
GO:0032012	biolink:NamedThing	regulation of ARF protein signal transduction	Any process that modulates the frequency, rate or extent of ARF protein signal transduction.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0032011	biolink:NamedThing	ARF protein signal transduction	A series of molecular signals within the cell that are mediated by a member of the ARF family of proteins switching to a GTP-bound active state.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0050871	biolink:NamedThing	positive regulation of B cell activation	Any process that activates or increases the frequency, rate or extent of B cell activation.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of B lymphocyte activation|up regulation of B cell activation|activation of B cell activation|stimulation of B cell activation|positive regulation of B-lymphocyte activation|positive regulation of B-cell activation|upregulation of B cell activation|up-regulation of B cell activation													biological_process											owl:Class	
GO:0071608	biolink:NamedThing	macrophage inflammatory protein-1 alpha production	The appearance of macrophage inflammatory protein 1 alpha due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	tmpzr1t_l9r_go_relaxed.owl	macrophage inflammatory protein production|MIP-1a production|chemokine (C-C motif) ligand 3 production|CCL3 production							mah	2010-02-05T04:24:17Z					biological_process											owl:Class	
GO:0038083	biolink:NamedThing	peptidyl-tyrosine autophosphorylation	The phosphorylation by a protein of one or more of its own tyrosine amino acid residues, or a tyrosine residue on an identical protein.	tmpzr1t_l9r_go_relaxed.owl	tyrosine autophosphorylation|receptor tyrosine kinase autophosphorylation|RTK autophosphorylation							bf	2012-02-01T02:14:18Z					biological_process											owl:Class	
GO:0009052	biolink:NamedThing	pentose-phosphate shunt, non-oxidative branch	The branch of the pentose-phosphate shunt which does not involve oxidation reactions. It comprises a series of sugar phosphate interconversions, starting with ribulose 5-P and producing fructose 6-P and glyceraldehyde 3-P.	tmpzr1t_l9r_go_relaxed.owl	pentose phosphate shunt, non-oxidative branch|pentose phosphate pathway, non-oxidative branch|pentose-phosphate pathway, non-oxidative branch				MetaCyc:P21-PWY|MetaCyc:NONOXIPENT-PWY									biological_process											owl:Class	
GO:1900209	biolink:NamedThing	negative regulation of cardiolipin metabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of cardiolipin metabolic process.	tmpzr1t_l9r_go_relaxed.owl	inhibition of cardiolipin metabolic process|downregulation of cardiolipin metabolism|down-regulation of diphosphatidylglycerol metabolic process|inhibition of cardiolipin metabolism|down regulation of cardiolipin metabolism|down-regulation of diphosphatidylglycerol metabolism|negative regulation of cardiolipin metabolism|negative regulation of diphosphatidylglycerol metabolic process|downregulation of diphosphatidylglycerol metabolism|down regulation of diphosphatidylglycerol metabolic process|inhibition of diphosphatidylglycerol metabolic process|downregulation of diphosphatidylglycerol metabolic process|down regulation of cardiolipin metabolic process|down-regulation of cardiolipin metabolism|negative regulation of diphosphatidylglycerol metabolism|inhibition of diphosphatidylglycerol metabolism|down regulation of diphosphatidylglycerol metabolism|downregulation of cardiolipin metabolic process|down-regulation of cardiolipin metabolic process							jl	2012-03-22T10:43:43Z					biological_process											owl:Class	
GO:0048208	biolink:NamedThing	COPII vesicle coating	The addition of COPII proteins and adaptor proteins to ER membranes during the formation of transport vesicles, forming a vesicle coat.	tmpzr1t_l9r_go_relaxed.owl	COPII vesicle coat formation|COPII coating of ER-derived vesicle|COPII vesicle coat assembly													biological_process											owl:Class	
GO:0090114	biolink:NamedThing	COPII-coated vesicle budding	The evagination of an endoplasmic reticulum membrane, resulting in formation of a COPII-coated vesicle.	tmpzr1t_l9r_go_relaxed.owl	ER exit|COPII vesicle budding|ER vesicle budding							tb	2009-12-06T09:21:16Z					biological_process											owl:Class	
GO:0003130	biolink:NamedThing	BMP signaling pathway involved in heart induction	A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, which contributes to heart induction.	tmpzr1t_l9r_go_relaxed.owl	BMP signalling pathway involved in heart induction							tb	2009-09-22T03:02:00Z					biological_process											owl:Class	
GO:0003134	biolink:NamedThing	endodermal-mesodermal cell signaling involved in heart induction	Any process that mediates the transfer of information from endodermal cells to mesodermal cells that contributes to heart induction.	tmpzr1t_l9r_go_relaxed.owl	endodermal-mesodermal cell signalling involved in heart induction							tb	2009-09-22T03:11:17Z					biological_process											owl:Class	
GO:1905488	biolink:NamedThing	positive regulation of anterior/posterior axon guidance	Any process that activates or increases the frequency, rate or extent of anterior/posterior axon guidance.	tmpzr1t_l9r_go_relaxed.owl	up regulation of anterior/posterior axon pathfinding|activation of anterior/posterior axon pathfinding|activation of anterior-posterior axon guidance|up-regulation of anterior-posterior axon guidance|up regulation of anterior/posterior axon guidance|activation of anterior/posterior axon guidance|upregulation of anterior-posterior axon guidance|positive regulation of anterior/posterior axon pathfinding|up-regulation of anterior/posterior axon pathfinding|up regulation of anterior-posterior axon guidance|up-regulation of anterior/posterior axon guidance|upregulation of anterior/posterior axon pathfinding|positive regulation of anterior-posterior axon guidance|upregulation of anterior/posterior axon guidance							hbye	2016-09-23T13:18:48Z					biological_process											owl:Class	
GO:0039689	biolink:NamedThing	negative stranded viral RNA replication	A viral genome replication process where the template genome is negative stranded, single stranded RNA ((-)ssRNA).	tmpzr1t_l9r_go_relaxed.owl	(-)ss viral RNA replication				VZ:1096			bf	2013-10-17T15:40:27Z					biological_process											owl:Class	
GO:0039696	biolink:NamedThing	RNA-templated viral transcription	A transcription process that uses viral RNA as a template.	tmpzr1t_l9r_go_relaxed.owl								bf	2013-10-28T13:28:01Z					biological_process											owl:Class	
GO:0032726	biolink:NamedThing	positive regulation of hepatocyte growth factor production	Any process that activates or increases the frequency, rate, or extent of hepatocyte growth factor production.	tmpzr1t_l9r_go_relaxed.owl	stimulation of hepatocyte growth factor production|activation of hepatocyte growth factor production|positive regulation of HGF production|up regulation of hepatocyte growth factor production|up-regulation of hepatocyte growth factor production|positive regulation of hepatocyte growth factor biosynthetic process|upregulation of hepatocyte growth factor production|positive regulation of scatter factor production											GO:0048177		biological_process											owl:Class	
GO:0032605	biolink:NamedThing	hepatocyte growth factor production	The appearance of hepatocyte growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	tmpzr1t_l9r_go_relaxed.owl	scatter factor production|HGF production|hepatocyte growth factor biosynthetic process											GO:0048175		biological_process											owl:Class	
GO:0044311	biolink:NamedThing	exoneme	A dense granule-like organelle of the apical complex of merozoites, released into the parasitophorous vacuole, mediating protease-dependent rupture and parasite exit from the infected erythrocyte.	tmpzr1t_l9r_go_relaxed.owl								jl	2010-02-18T03:29:56Z					cellular_component											owl:Class	
GO:0009419	biolink:NamedThing	pilus tip	The pointed extremity furthest from the cell of a pilus.	tmpzr1t_l9r_go_relaxed.owl	fimbrial tip													cellular_component											owl:Class	
GO:0009289	biolink:NamedThing	pilus	A proteinaceous hair-like appendage on the surface of bacteria ranging from 2-8 nm in diameter.	tmpzr1t_l9r_go_relaxed.owl	fimbria|fimbrium|pili|fimbriae				Wikipedia:Pilus									cellular_component											owl:Class	
GO:0031152	biolink:NamedThing	aggregation involved in sorocarp development	The process whose specific outcome is the progression of the aggregate over time, from its formation to the point when a slug is formed. Aggregate development begins in response to starvation and continues by the chemoattractant-mediated movement of cells toward each other. The aggregate is a multicellular structure that gives rise to the slug.	tmpzr1t_l9r_go_relaxed.owl	aggregation during fruiting body development|aggregate development involved in sorocarp development													biological_process											owl:Class	
GO:0061093	biolink:NamedThing	negative regulation of phospholipid translocation	Any process that decreases the frequency, rate or extent of the translocation, or flipping, of phospholipid molecules from one monolayer of a membrane bilayer to the opposite monolayer.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-04-26T01:54:22Z					biological_process											owl:Class	
GO:2001128	biolink:NamedThing	methane biosynthetic process from methylamine	The chemical reactions and pathways resulting in the formation of a methane from a methylamine.	tmpzr1t_l9r_go_relaxed.owl								jl	2011-10-13T10:23:25Z					biological_process											owl:Class	
GO:1905839	biolink:NamedThing	negative regulation of telomeric D-loop disassembly	Any process that stops, prevents or reduces the frequency, rate or extent of telomeric D-loop disassembly.	tmpzr1t_l9r_go_relaxed.owl	inhibition of telomeric D-loop disassembly|down regulation of telomeric D-loop disassembly|down-regulation of telomeric D-loop disassembly|downregulation of telomeric D-loop disassembly							nc	2017-01-18T11:01:47Z					biological_process											owl:Class	
GO:0061820	biolink:NamedThing	telomeric D-loop disassembly	A telomere loop disassembly process that results in the disassembly of telomeric D-loops. A telomeric D-loop is a three-stranded DNA displacement loop that forms at the site where the telomeric 3' single-stranded DNA overhang (formed of the repeat sequence TTAGGG in mammals) is tucked back inside the double-stranded component of telomeric DNA molecule, thus forming a t-loop or telomeric-loop and protecting the chromosome terminus.	tmpzr1t_l9r_go_relaxed.owl								dph						biological_process											owl:Class	
GO:2000351	biolink:NamedThing	regulation of endothelial cell apoptotic process	Any process that modulates the frequency, rate or extent of endothelial cell apoptotic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of endothelial cell programmed cell death by apoptosis|regulation of apoptosis of endothelial cells|regulation of programmed cell death of endothelial cells by apoptosis|regulation of programmed cell death, endothelial cells|regulation of killing of endothelial cells|regulation of endothelial cell apoptosis							mah	2011-02-03T10:43:16Z					biological_process											owl:Class	
GO:0072577	biolink:NamedThing	endothelial cell apoptotic process	Any apoptotic process in an endothelial cell. An endothelial cell comprises the outermost layer or lining of anatomical structures and can be squamous or cuboidal.	tmpzr1t_l9r_go_relaxed.owl	programmed cell death, endothelial cells|killing of endothelial cells|endothelial cell apoptosis|programmed cell death of endothelial cells by apoptosis|apoptosis of endothelial cells|endothelial cell programmed cell death by apoptosis							mah	2011-02-02T03:56:24Z					biological_process											owl:Class	
GO:2000795	biolink:NamedThing	negative regulation of epithelial cell proliferation involved in lung morphogenesis	Any process that stops, prevents or reduces the frequency, rate or extent of epithelial cell proliferation involved in lung morphogenesis.	tmpzr1t_l9r_go_relaxed.owl								pr	2011-06-25T07:22:42Z					biological_process											owl:Class	
GO:0044336	biolink:NamedThing	canonical Wnt signaling pathway involved in negative regulation of apoptotic process	The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes involved in the negative regulation of apoptotic process.	tmpzr1t_l9r_go_relaxed.owl	canonical Wnt receptor signaling pathway involved in negative regulation of apoptotic process|canonical Wnt receptor signalling pathway involved in negative regulation of apoptosis|canonical Wnt receptor signaling pathway involved in negative regulation of apoptosis							jl	2010-08-20T03:07:53Z					biological_process											owl:Class	
GO:0001808	biolink:NamedThing	negative regulation of type IV hypersensitivity	Any process that stops, prevents, or reduces the rate of type IV hypersensitivity, a type of inflammatory response.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of type IV hypersensitivity|downregulation of type IV hypersensitivity|down regulation of type IV hypersensitivity|inhibition of type IV hypersensitivity													biological_process											owl:Class	
GO:0001806	biolink:NamedThing	type IV hypersensitivity	An inflammatory response driven by T cell recognition of processed soluble or cell-associated antigens leading to cytokine release and leukocyte activation.	tmpzr1t_l9r_go_relaxed.owl	delayed-type hypersensitivity|delayed hypersensitivity response				Wikipedia:Type_IV_hypersensitivity							GO:0016069		biological_process											owl:Class	
GO:0001999	biolink:NamedThing	renal response to blood flow involved in circulatory renin-angiotensin regulation of systemic arterial blood pressure	The physiological response of the kidneys to a decrease in blood flow.	tmpzr1t_l9r_go_relaxed.owl	renal response to blood flow during renin-angiotensin control of blood pressure													biological_process											owl:Class	
GO:1902359	biolink:NamedThing	Notch signaling pathway involved in somitogenesis	Any Notch signaling pathway that is involved in somitogenesis.	tmpzr1t_l9r_go_relaxed.owl	Notch receptor signalling pathway involved in somitogenesis|Notch-receptor signaling pathway involved in somitogenesis|Notch receptor signaling pathway involved in somitogenesis|N signalling pathway involved in somitogenesis|Notch signalling pathway involved in formation of mesodermal clusters|Notch receptor signaling pathway involved in formation of mesodermal clusters|N signaling pathway involved in somitogenesis|Notch receptor signalling pathway involved in formation of mesodermal clusters|N signalling pathway involved in formation of mesodermal clusters|Notch-receptor signalling pathway involved in formation of mesodermal clusters|Notch signalling pathway involved in somitogenesis|Notch-receptor signalling pathway involved in somitogenesis|N signaling pathway involved in formation of mesodermal clusters|Notch signaling pathway involved in formation of mesodermal clusters|Notch-receptor signaling pathway involved in formation of mesodermal clusters							dph	2013-08-14T17:31:43Z					biological_process											owl:Class	
GO:0061066	biolink:NamedThing	positive regulation of dauer larval development	Any process that increases the rate, frequency, or extent of dauer larval development, the process whose specific outcome is the progression of the dauer larva over time, through the facultative diapause of the dauer (enduring) larval stage, with specialized traits adapted for dispersal and long-term survival, with elevated stress resistance and without feeding.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-03-11T01:09:11Z					biological_process											owl:Class	
GO:0040024	biolink:NamedThing	dauer larval development	The process whose specific outcome is the progression of the dauer larva over time, through the facultative diapause of the dauer (enduring) larval stage, with specialized traits adapted for dispersal and long-term survival, with elevated stress resistance and without feeding.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:2000435	biolink:NamedThing	negative regulation of protein neddylation	Any process that stops, prevents or reduces the frequency, rate or extent of protein neddylation.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of RUB1-protein conjugation							vw	2011-03-03T02:05:56Z					biological_process											owl:Class	
GO:1902044	biolink:NamedThing	regulation of Fas signaling pathway	Any process that modulates the frequency, rate or extent of Fas signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	regulation of Fas receptor signaling pathway|regulation of CD95 signaling pathway|regulation of FasR signaling pathway|regulation of Apo-1 signaling pathway|regulation of FAS ligand-Fas signaling pathway|regulation of Fas-FasL signaling pathway|regulation of FasL signaling pathway							lb	2013-04-03T07:21:23Z					biological_process											owl:Class	
GO:0048616	biolink:NamedThing	post-embryonic anterior midgut (ectodermal) morphogenesis	The process in which the anatomical structures of the anterior midgut (ectodermal) are generated and organized, during the post-embryonic phase.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0048614	biolink:NamedThing	post-embryonic ectodermal digestive tract morphogenesis	The process, occurring during the post-embryonic phase, by which the anatomical structures of the ectodermal gut are generated and organized.	tmpzr1t_l9r_go_relaxed.owl	post-embryonic ectodermal gut morphogenesis													biological_process											owl:Class	
GO:0033372	biolink:NamedThing	establishment of protease localization to mast cell secretory granule	The directed movement of a protease to a location within a secretory granule in a mast cell.	tmpzr1t_l9r_go_relaxed.owl	establishment of protease localization in mast cell secretory granule|establishment of protease localisation in mast cell secretory granule													biological_process											owl:Class	
GO:0016559	biolink:NamedThing	peroxisome fission	The division of a mature peroxisome within a cell to form two or more separate peroxisome compartments.	tmpzr1t_l9r_go_relaxed.owl	peroxisome division|peroxisome proliferation													biological_process											owl:Class	
GO:0007031	biolink:NamedThing	peroxisome organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a peroxisome. A peroxisome is a small, membrane-bounded organelle that uses dioxygen (O2) to oxidize organic molecules.	tmpzr1t_l9r_go_relaxed.owl	peroxisome organisation|peroxisome-assembly ATPase activity|peroxisome organization and biogenesis													biological_process											owl:Class	
GO:1905910	biolink:NamedThing	negative regulation of dauer entry	Any process that stops, prevents or reduces the frequency, rate or extent of dauer entry.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of nematode entry into dormancy|inhibition of nematode entry into dormancy|down regulation of dauer entry|down-regulation of dauer entry|downregulation of dauer entry|downregulation of nematode entry into dormancy|inhibition of dauer entry|down-regulation of nematode entry into dormancy|down regulation of nematode entry into dormancy							hbye	2017-02-06T15:34:11Z					biological_process											owl:Class	
GO:0071475	biolink:NamedThing	cellular hyperosmotic salinity response	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, an increase in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.	tmpzr1t_l9r_go_relaxed.owl	cellular response to hyperosmotic salt stress							mah	2009-12-18T11:52:06Z					biological_process											owl:Class	
GO:0097711	biolink:NamedThing	ciliary basal body-plasma membrane docking	The docking of a cytosolic centriole/basal body to the plasma membrane via the ciliary transition fibers. In some species this may happen via an intermediate step, by first docking to the ciliary vesicle via the ciliary transition fibers. The basal body-ciliary vesicle then relocates to the plasma membrane, followed by the ciliary vesicle fusing with the plasma membrane, effectively attaching the basal body to the plasma membrane.	tmpzr1t_l9r_go_relaxed.owl	anchoring of the basal body to the plasma membrane|ciliary basal body docking				Reactome:R-HSA-5620912.1	Basal bodies in jawed vertebrates appear to first attach to a ciliary vesicle. It is unclear how specific this is to jawed vertebrates or if other organisms also employ this sequence. Some species like Giardia intestinalis do not relocate their basal bodies to the plasma membrane, but have their axonemes extend through the cytosol to then protrude out of the cell to form flagella.		pr	2016-08-05T16:12:33Z					biological_process											owl:Class	
GO:0048654	biolink:NamedThing	anther morphogenesis	The process in which the anatomical structures of the anther are generated and organized.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0097227	biolink:NamedThing	sperm annulus	The ring-like, filamentous structure located at the distal end of the midpiece of the sperm flagellum; the annulus is thought to form a diffusion barrier between the midpiece and the principal piece and serve as a stabilizing structure for tail rigidity.	tmpzr1t_l9r_go_relaxed.owl								pr	2012-01-25T01:26:17Z					cellular_component											owl:Class	
GO:0036126	biolink:NamedThing	sperm flagellum	A microtubule-based flagellum (or cilium) that is part of a sperm, a mature male germ cell that develops from a spermatid.	tmpzr1t_l9r_go_relaxed.owl	sperm cilium|sperm tail					Note that cilia and eukaryotic flagella are deemed to be equivalent. In this case community usage is always 'flagellum', hence the primary term name, but the cilium parentage is deliberate.		bf	2012-02-28T02:39:00Z					cellular_component											owl:Class	
GO:0043226	biolink:NamedThing	organelle	Organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, and prokaryotic structures such as anammoxosomes and pirellulosomes. Excludes the plasma membrane.	tmpzr1t_l9r_go_relaxed.owl					NIF_Subcellular:sao1539965131|Wikipedia:Organelle									cellular_component											owl:Class	
GO:0120140	biolink:NamedThing	negative regulation of phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity	Any process that stops, prevents or reduces the frequency, rate or extent of phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity.	tmpzr1t_l9r_go_relaxed.owl								krc	2018-03-22T16:32:59Z					biological_process											owl:Class	
GO:0071009	biolink:NamedThing	U4atac/U6atac x U5 tri-snRNP complex	A spliceosomal snRNP complex that is formed by the association of the U4atac/U6atac and U5 snRNPs.	tmpzr1t_l9r_go_relaxed.owl	U4atac/U6atac.U5 snRNP complex							mah	2009-07-30T12:00:35Z					cellular_component											owl:Class	
GO:0005682	biolink:NamedThing	U5 snRNP	A ribonucleoprotein complex that contains small nuclear RNA U5, a heptameric ring of Sm proteins, as well as several proteins that are unique to the U5 snRNP, most of which remain associated with the U5 snRNA both while the U5 snRNP is free or assembled into a series of spliceosomal complexes.	tmpzr1t_l9r_go_relaxed.owl	snRNP U5													cellular_component											owl:Class	
GO:0043475	biolink:NamedThing	pigment metabolic process involved in pigment accumulation	The chemical reactions and pathways involving a pigment, any general or particular coloring matter in living organisms, as part of the accumulation of pigment.	tmpzr1t_l9r_go_relaxed.owl	pigment metabolism during pigment accumulation|pigment metabolic process during pigment accumulation													biological_process											owl:Class	
GO:0032211	biolink:NamedThing	negative regulation of telomere maintenance via telomerase	Any process that stops, prevents, or reduces the frequency, rate or extent of the addition of telomeric repeats by telomerase.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of telomere maintenance via telomerase activity|downregulation of telomere maintenance via telomerase activity|down regulation of telomere maintenance via telomerase activity|inhibition of telomere maintenance via telomerase													biological_process											owl:Class	
GO:0003338	biolink:NamedThing	metanephros morphogenesis	The process in which the anatomical structures of the metanephros are generated and organized.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-11-24T09:32:09Z					biological_process											owl:Class	
GO:0019081	biolink:NamedThing	viral translation	A process by which viral mRNA is translated into viral protein, using the host cellular machinery.	tmpzr1t_l9r_go_relaxed.owl	viral protein synthesis|viral protein biosynthetic process|viral protein biosynthesis|viral protein anabolism|viral protein formation													biological_process											owl:Class	
GO:0002461	biolink:NamedThing	tolerance induction dependent upon immune response	Tolerance induction dependent upon an immune response, typically a response by a mature T or B cell in the periphery resulting tolerance towards an antigen via induction of anergy, cellular deletion, or regulatory T cell activation.	tmpzr1t_l9r_go_relaxed.owl	immune response-dependent tolerance induction													biological_process											owl:Class	
GO:0060012	biolink:NamedThing	synaptic transmission, glycinergic	The vesicular release of glycine from a presynapse, across a chemical synapse, the subsequent activation of glycine receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse.	tmpzr1t_l9r_go_relaxed.owl	glycinergic synaptic transmission													biological_process											owl:Class	
GO:0045323	biolink:NamedThing	interleukin-1 receptor complex	A protein complex that binds interleukin-1; comprises an alpha and a beta subunit.	tmpzr1t_l9r_go_relaxed.owl	IL-1 receptor complex													cellular_component											owl:Class	
GO:0071022	biolink:NamedThing	U12-type post-spliceosomal complex	A spliceosomal complex that is formed following the second splicing event and contains the spliced product, the excised intron, and three snRNPs, U5, U12 and U6atac.	tmpzr1t_l9r_go_relaxed.owl	AT-AC post-spliceosomal complex|yeast U12-type spliceosomal complex A2-3|minor post-spliceosomal complex|mammalian U12-type spliceosomal complex C2							mah	2009-07-30T12:00:35Z					cellular_component											owl:Class	
GO:0005691	biolink:NamedThing	U6atac snRNP	A ribonucleoprotein complex that contains small nuclear RNA U6atac, the Lsm2-8 heptameric ring complex, as well as several proteins that are unique to the U6atac snRNP, most of which remain associated with the U6atac snRNA both while the U6atac snRNP is free or assembled into the U4atac/U6atac snRNP or into a series of spliceosomal complexes.	tmpzr1t_l9r_go_relaxed.owl	snRNP U6atac													cellular_component											owl:Class	
GO:0005251	biolink:NamedThing	delayed rectifier potassium channel activity	Enables the transmembrane transfer of a potassium ion by a delayed rectifying voltage-gated channel. A delayed rectifying current-voltage relation is one where channel activation kinetics are time-dependent, and inactivation is slow.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-5577237|Reactome:R-HSA-5577050									molecular_function											owl:Class	
GO:0045278	biolink:NamedThing	plasma membrane respiratory chain complex IV	A part of the respiratory chain located in the plasma membrane, containing the 13 polypeptide subunits of cytochrome c oxidase, including cytochrome a and cytochrome a3. Catalyzes the oxidation of reduced cytochrome c by dioxygen (O2). Examples of this component are found in bacterial species.	tmpzr1t_l9r_go_relaxed.owl	cytochrome c oxidase complex|respiratory chain complex IV											GO:0045288		cellular_component											owl:Class	
GO:0070826	biolink:NamedThing	paraferritin complex	A cytoplasmic protein complex that contains integrin, mobilferrin and a flavin monooxygenase, is capable of reducing Fe(III) to Fe(II) utilizing NADPH, and is involved in iron transport. Fe(II) is required in the cell as the substrate for ferrochelatase in the synthesis of heme.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-07-23T03:05:08Z					cellular_component											owl:Class	
GO:1902160	biolink:NamedThing	negative regulation of cyclic nucleotide-gated ion channel activity	Any process that stops, prevents or reduces the frequency, rate or extent of cyclic nucleotide-gated ion channel activity.	tmpzr1t_l9r_go_relaxed.owl	inhibition of cyclic nucleotide-gated ion channel activity|downregulation of cyclic nucleotide-gated ion channel activity|downregulation of cyclic nucleotide gated ion channel activity|downregulation of cyclic nucleotide activated ion channel activity|negative regulation of cyclic nucleotide-activated ion channel activity|inhibition of cyclic nucleotide-activated ion channel activity|down-regulation of cyclic nucleotide activated ion channel activity|down-regulation of cyclic nucleotide-gated ion channel activity|downregulation of cyclic nucleotide-activated ion channel activity|down regulation of cyclic nucleotide-gated ion channel activity|inhibition of cyclic nucleotide activated ion channel activity|inhibition of cyclic nucleotide gated ion channel activity|down regulation of cyclic nucleotide activated ion channel activity|negative regulation of cyclic nucleotide activated ion channel activity|down regulation of cyclic nucleotide-activated ion channel activity|down-regulation of cyclic nucleotide gated ion channel activity|down regulation of cyclic nucleotide gated ion channel activity|down-regulation of cyclic nucleotide-activated ion channel activity|negative regulation of cyclic nucleotide gated ion channel activity							sl	2013-05-21T19:24:35Z					biological_process											owl:Class	
GO:0035882	biolink:NamedThing	defecation rhythm	The rhythmic process of defecation that consists of an intestinal oscillator which regulates calcium waves. These waves in turn control a stereotypical, three-part pattern of muscle contractions. In some organisms, defecation can recur with a regularity more frequent than every 24 hours. For example, in a well-fed Caenorhabditis elegans, the defecation motor program occurs approximately every 45 seconds, and is temperature- and touch-compensated.	tmpzr1t_l9r_go_relaxed.owl	DMP|defecation cycle|defecation behavior|defecation motor program							bf	2011-06-06T11:36:35Z					biological_process											owl:Class	
GO:0002087	biolink:NamedThing	regulation of respiratory gaseous exchange by nervous system process	A process carried out by the nervous system that is required for the proper control of respiratory gaseous exchange. This process occurs in the respiratory center of the brain in vertebrates.	tmpzr1t_l9r_go_relaxed.owl	neurological control of breathing|regulation of respiratory gaseous exchange by neurological system process													biological_process											owl:Class	
GO:0045880	biolink:NamedThing	positive regulation of smoothened signaling pathway	Any process that activates or increases the frequency, rate or extent of smoothened signaling.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of hedgehog signaling pathway|stimulation of smoothened signaling pathway|positive regulation of smoothened signalling pathway|up-regulation of smoothened signaling pathway|positive regulation of smoothened receptor activity by patched|upregulation of smoothened signaling pathway|positive regulation of smoothened by patched|positive regulation of hh signaling pathway|up regulation of smoothened signaling pathway|activation of smoothened signaling pathway											GO:0045878		biological_process											owl:Class	
GO:0060939	biolink:NamedThing	epicardium-derived cardiac fibroblast cell development	The process whose specific outcome is the progression of an epicardial-derived cardiac fibroblast over time, from its formation to the mature state. A epicardial-derived cardiac fibroblast is a connective tissue cell of the heart that arises from the epicardium and secretes an extracellular matrix rich in collagen and other macromolecules.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-09-29T01:29:19Z					biological_process											owl:Class	
GO:0046599	biolink:NamedThing	regulation of centriole replication	Any process that modulates the frequency, rate or extent of the formation of a daughter centriole of an existing centriole.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1902319	biolink:NamedThing	DNA strand elongation involved in nuclear cell cycle DNA replication	Any DNA strand elongation that is involved in nuclear cell cycle DNA replication.	tmpzr1t_l9r_go_relaxed.owl	DNA strand elongation involved in DNA replication involved in S-phase|DNA strand elongation involved in DNA replication involved in S phase|DNA strand elongation involved in DNA replication during S phase							jl	2013-07-23T14:00:41Z					biological_process											owl:Class	
GO:1990695	biolink:NamedThing	intrinsic component of Golgi trans cisterna membrane	The component of the Golgi trans cisterna membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.	tmpzr1t_l9r_go_relaxed.owl	intrinsic component of trans-Golgi cisterna membrane							bhm	2015-03-12T10:36:02Z					cellular_component											owl:Class	
GO:0048297	biolink:NamedThing	negative regulation of isotype switching to IgA isotypes	Any process that stops, prevents, or reduces the frequency, rate or extent of isotype switching to IgA isotypes.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of isotype switching to IgA isotypes|downregulation of isotype switching to IgA isotypes|negative regulation of class switch recombination to IgA isotypes|inhibition of isotype switching to IgA isotypes|negative regulation of class switching to IgA isotypes|negative regulation of isotype switch recombination to IgA isotypes|down regulation of isotype switching to IgA isotypes													biological_process											owl:Class	
GO:2000546	biolink:NamedThing	positive regulation of endothelial cell chemotaxis to fibroblast growth factor	Any process that activates or increases the frequency, rate or extent of endothelial cell chemotaxis to fibroblast growth factor.	tmpzr1t_l9r_go_relaxed.owl								ebc	2011-04-03T07:17:27Z					biological_process											owl:Class	
GO:0034162	biolink:NamedThing	toll-like receptor 9 signaling pathway	Any series of molecular signals generated as a consequence of binding to toll-like receptor 9.	tmpzr1t_l9r_go_relaxed.owl	toll-like receptor 9 signalling pathway|TLR9 signaling pathway													biological_process											owl:Class	
GO:0048910	biolink:NamedThing	afferent axon development in anterior lateral line nerve	The process whose specific outcome is the progression of an afferent axon in the anterior lateral line nerve over time from its formation to the mature structure. This process includes axonogenesis and pathfinding of the afferent axons in the anterior lateral line nerve.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0010995	biolink:NamedThing	free ubiquitin chain depolymerization	The process in which free ubiquitin chains, compounds composed of a large number of ubiquitin monomers, are broken down.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-06-03T11:45:42Z					biological_process											owl:Class	
GO:0048715	biolink:NamedThing	negative regulation of oligodendrocyte differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of oligodendrocyte differentiation.	tmpzr1t_l9r_go_relaxed.owl	inhibition of oligodendrocyte differentiation|down-regulation of oligodendrocyte differentiation|down regulation of oligodendrocyte differentiation|downregulation of oligodendrocyte differentiation													biological_process											owl:Class	
GO:0004979	biolink:NamedThing	beta-endorphin receptor activity	Combining with beta-endorphin, and transmitting the signal across the membrane by activating an associated G-protein. Beta-endorphin is a peptide, 31 amino acids long, resulting from processing of the precursor proopiomelanocortin (POMC).	tmpzr1t_l9r_go_relaxed.owl	mu-opioid receptor activity													molecular_function											owl:Class	
GO:1900734	biolink:NamedThing	positive regulation of polyketide biosynthetic process	Any process that activates or increases the frequency, rate or extent of polyketide biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	activation of polyketide formation|positive regulation of polyketide synthesis|up regulation of polyketide biosynthesis|activation of polyketide anabolism|up-regulation of polyketide formation|activation of polyketide synthesis|upregulation of polyketide synthesis|up regulation of polyketide anabolism|up-regulation of polyketide biosynthetic process|up-regulation of polyketide synthesis|positive regulation of polyketide formation|activation of polyketide biosynthesis|positive regulation of polyketide biosynthesis|upregulation of polyketide anabolism|upregulation of polyketide biosynthesis|upregulation of polyketide biosynthetic process|positive regulation of polyketide anabolism|up-regulation of polyketide anabolism|up-regulation of polyketide biosynthesis|up regulation of polyketide biosynthetic process|activation of polyketide biosynthetic process|up regulation of polyketide formation|up regulation of polyketide synthesis|upregulation of polyketide formation							di	2012-05-26T01:30:10Z					biological_process											owl:Class	
GO:0006182	biolink:NamedThing	cGMP biosynthetic process	The chemical reactions and pathways resulting in the formation of cyclic GMP, guanosine 3',5'-phosphate.	tmpzr1t_l9r_go_relaxed.owl	cGMP biosynthesis|cGMP anabolism|cGMP formation|cGMP synthesis													biological_process											owl:Class	
GO:0000142	biolink:NamedThing	cellular bud neck contractile ring	A contractile ring, i.e. a cytoskeletal structure composed of actin filaments and myosin, that forms beneath the plasma membrane at the mother-bud neck in mitotic cells that divide by budding in preparation for completing cytokinesis. An example of this structure is found in Saccharomyces cerevisiae.	tmpzr1t_l9r_go_relaxed.owl	neck ring													cellular_component											owl:Class	
GO:0062246	biolink:NamedThing	exocytic vesicle lumen	The volume enclosed by an exocytic vesicle.	tmpzr1t_l9r_go_relaxed.owl								dph	2020-04-27T12:10:09Z					cellular_component											owl:Class	
GO:0072244	biolink:NamedThing	metanephric glomerular epithelium development	The process whose specific outcome is the progression of the metanephric glomerular epithelium over time, from its formation to the mature structure. The metanephric glomerular epithelium is an epithelial tissue that covers the outer surfaces of the glomerulus in the metanephros. The metanephric glomerular epithelium consists of both parietal and visceral epithelium. Metanephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. A metanephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the metanephros.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-03-19T03:38:47Z					biological_process											owl:Class	
GO:0039625	biolink:NamedThing	viral inner capsid	The inner layer of a double or triple concentric icosahedral capsid. Inner capsids are part of reoviridae and cystoviridae virions.	tmpzr1t_l9r_go_relaxed.owl	inner capsid							bf	2012-07-18T04:05:35Z					cellular_component											owl:Class	
GO:0070378	biolink:NamedThing	positive regulation of ERK5 cascade	Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the ERK5 cascade.	tmpzr1t_l9r_go_relaxed.owl	up regulation of BMK cascade|stimulation of BMK cascade|upregulation of BMK cascade|positive regulation of ERK5 signaling pathway|positive regulation of BMK signalling pathway|positive regulation of BMK1 cascade|up-regulation of BMK cascade|positive regulation of BMK cascade|positive regulation of MAPK7 cascade|positive regulation of BMK signaling pathway|activation of BMK cascade													biological_process											owl:Class	
GO:0021554	biolink:NamedThing	optic nerve development	The process whose specific outcome is the progression of the optic nerve over time, from its formation to the mature structure. The sensory optic nerve originates from the bipolar cells of the retina and conducts visual information to the brainstem. The optic nerve exits the back of the eye in the orbit, enters the optic canal, and enters the central nervous system at the optic chiasm (crossing) where the nerve fibers become the optic tract just prior to entering the hindbrain.	tmpzr1t_l9r_go_relaxed.owl	cranial nerve II development|cranial nerve 2 development|CN II development													biological_process											owl:Class	
GO:1901585	biolink:NamedThing	regulation of acid-sensing ion channel activity	Any process that modulates the frequency, rate or extent of acid-sensing ion channel activity.	tmpzr1t_l9r_go_relaxed.owl	regulation of ASIC activity							jl	2012-11-07T13:37:24Z					biological_process											owl:Class	
GO:0048929	biolink:NamedThing	efferent axon development in posterior lateral line nerve	The process whose specific outcome is the progression of an efferent axon in the posterior lateral line nerve over time from its formation to the mature structure. This process includes axonogenesis and pathfinding of the efferent axons in the posterior lateral line nerve.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0043594	biolink:NamedThing	outer endospore membrane	The outer membrane around a bacterial endospore, located between the endospore cortex and endospore coat.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0043591	biolink:NamedThing	endospore external encapsulating structure	The structures that lie outside the inner membrane and surround the entire endospore; consists of a peptidoglycan-containing inner layer (the endospore cortex) surrounded by a multilayered proteinaceous coat. An exosporium may be present as an extreme outer layer.	tmpzr1t_l9r_go_relaxed.owl	endospore wall|spore wall|peptidoglycan-based spore wall											GO:0055030		cellular_component											owl:Class	
GO:1905896	biolink:NamedThing	positive regulation of cellular response to tunicamycin	Any process that activates or increases the frequency, rate or extent of cellular response to tunicamycin.	tmpzr1t_l9r_go_relaxed.owl	up regulation of cellular response to tunicamycin|activation of cellular response to tunicamycin|up-regulation of cellular response to tunicamycin|upregulation of cellular response to tunicamycin							bc	2017-02-01T11:36:51Z					biological_process											owl:Class	
GO:1904577	biolink:NamedThing	cellular response to tunicamycin	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tunicamycin stimulus.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-08-19T18:01:58Z					biological_process											owl:Class	
GO:0060996	biolink:NamedThing	dendritic spine development	The process whose specific outcome is the progression of the dendritic spine over time, from its formation to the mature structure. A dendritic spine is a protrusion from a dendrite and a specialized subcellular compartment involved in synaptic transmission.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-01-20T09:06:33Z					biological_process											owl:Class	
GO:0021794	biolink:NamedThing	thalamus development	The process in which the thalamus changes over time, from its initial formation to its mature state.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0075524	biolink:NamedThing	ribosomal skipping	A translation process in which a specific viral peptide prevents the ribosome from covalently linking a new inserted amino acid, and lets it continue translation, thereby cleaving the nascent protein while allowing translation to continue.	tmpzr1t_l9r_go_relaxed.owl					VZ:914	This term is intended to annotate gene products involved in the process of ribosomal skipping, not viral proteins produced by this translation process.		jl	2011-08-03T03:19:37Z					biological_process											owl:Class	
GO:1990986	biolink:NamedThing	DNA recombinase disassembly	The disaggregation of a DNA recombinase complex into its constituent strand exchange proteins (recombinases).	tmpzr1t_l9r_go_relaxed.owl	Rad51 nucleoprotein filament disassembly							pg	2016-11-18T13:13:56Z					biological_process											owl:Class	
GO:0019244	biolink:NamedThing	lactate biosynthetic process from pyruvate	The chemical reactions and pathways resulting in the formation of lactate from other compounds, including pyruvate.	tmpzr1t_l9r_go_relaxed.owl	lactate formation from pyruvate|lactate anabolism from pyruvate|lactate synthesis from pyruvate|pyruvate fermentation to lactate				Reactome:R-HSA-71849.1									biological_process											owl:Class	
GO:0030589	biolink:NamedThing	pseudocleavage involved in syncytial blastoderm formation	Formation of furrows in the cytoplasm between nuclei during cell cycles in embryos that contribute to the formation of the syncytial blastoderm. An example of this process is found in Drosophila melanogaster.	tmpzr1t_l9r_go_relaxed.owl	pseudocleavage during syncytial blastoderm formation													biological_process											owl:Class	
GO:0120151	biolink:NamedThing	positive regulation of mitotic actomyosin contractile ring disassembly	Any process that activates or increases the frequency, rate or extent of mitotic actomyosin contractile ring disassembly.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of mitotic actomyosin ring disassembly|positive regulation of mitotic contractile actomyosin ring disassembly|positive regulation of mitotic cytokinetic ring disassembly|positive regulation of mitotic CAR disassembly|positive regulation of mitotic constriction ring disassembly							krc	2018-04-24T15:06:51Z					biological_process											owl:Class	
GO:0032696	biolink:NamedThing	negative regulation of interleukin-13 production	Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-13 production.	tmpzr1t_l9r_go_relaxed.owl	downregulation of interleukin-13 production|inhibition of interleukin-13 production|down-regulation of interleukin-13 production|negative regulation of IL-13 production|negative regulation of interleukin-13 secretion|down regulation of interleukin-13 production|negative regulation of interleukin-13 biosynthetic process											GO:2000666|GO:0045367		biological_process											owl:Class	
GO:0002347	biolink:NamedThing	response to tumor cell	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a tumor cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0000745	biolink:NamedThing	nuclear migration involved in conjugation with mutual genetic exchange	The net movement of nuclei towards one another, leading to the bilateral transfer of genetic material in organisms undergoing conjugation without cellular fusion.	tmpzr1t_l9r_go_relaxed.owl	nuclear migration involved in conjugation without cellular fusion|nuclear exchange during conjugation without cellular fusion													biological_process											owl:Class	
GO:0000748	biolink:NamedThing	conjugation with mutual genetic exchange	A conjugation process that results in the mutual exchange and union of only genetic information between compatible mating types. Conjugation without cellular fusion requires direct cellular contact between the organisms without plasma membrane fusion. The organisms involved in conjugation without cellular fusion separate after nuclear exchange.	tmpzr1t_l9r_go_relaxed.owl	conjugation without cellular fusion													biological_process											owl:Class	
GO:0004735	biolink:NamedThing	pyrroline-5-carboxylate reductase activity	Catalysis of the reaction: L-proline + NADP+ = 1-pyrroline-5-carboxylate + NADPH + H+.	tmpzr1t_l9r_go_relaxed.owl	L-proline oxidase activity|NADPH-L-delta1-pyrroline carboxylic acid reductase activity|P5CR activity|1-pyrroline-5-carboxylate reductase activity|L-proline-NAD(P)+ 5-oxidoreductase activity|L-proline:NAD(P)+ 5-oxidoreductase activity				MetaCyc:PYRROLINECARBREDUCT-RXN|Reactome:R-HSA-70664|EC:1.5.1.2|Reactome:R-HSA-6783939|RHEA:14109|Reactome:R-HSA-6783955									molecular_function											owl:Class	
GO:0061056	biolink:NamedThing	sclerotome development	The progression of the sclerotome over time, from its initial formation to the mature structure. The sclerotome is the portion of the somite that will give rise to a vertebra.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-03-02T12:12:40Z					biological_process											owl:Class	
GO:0090391	biolink:NamedThing	granum assembly	A process that is carried out at the cellular level which results in the assembly of a granum. A granum is a distinct stack of lamellae seen within chloroplasts.	tmpzr1t_l9r_go_relaxed.owl	grana formation							tb	2010-12-08T04:25:46Z					biological_process											owl:Class	
GO:0004921	biolink:NamedThing	interleukin-11 receptor activity	Combining with interleukin-11 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	IL-11R|gp130|IL-11 receptor activity													molecular_function											owl:Class	
GO:0038154	biolink:NamedThing	interleukin-11-mediated signaling pathway	A series of molecular signals initiated by the binding of interleukin-11 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.	tmpzr1t_l9r_go_relaxed.owl	interleukin-11-mediated signalling pathway|IL-11-mediated signaling pathway							bf	2012-05-11T11:48:37Z					biological_process											owl:Class	
GO:0015135	biolink:NamedThing	glucuronate transmembrane transporter activity	Enables the transfer of glucuronate from one side of a membrane to the other. Glucuronate is the uronic acid formally derived from glucose by oxidation of the hydroxymethylene group at C-6 to a carboxyl group.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0015738	biolink:NamedThing	glucuronate transmembrane transport	The process in which glucuronate is transported across a lipid bilayer, from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	glucuronate transport													biological_process											owl:Class	
GO:0061118	biolink:NamedThing	regulation of positive chemotaxis to cAMP	Any process that modulates the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-05-17T07:47:47Z					biological_process											owl:Class	
GO:0043327	biolink:NamedThing	chemotaxis to cAMP	The directed movement of a motile cell or organism in response to the presence of 3',5'-cAMP.	tmpzr1t_l9r_go_relaxed.owl	chemotaxis to adenosine 3',5'-cyclophosphate|chemotaxis to 3',5'-cAMP|chemotaxis to cyclic AMP|chemotaxis to 3',5' cAMP													biological_process											owl:Class	
GO:0072283	biolink:NamedThing	metanephric renal vesicle morphogenesis	The process in which the anatomical structures of the metanephric renal vesicle are generated and organized. The renal vesicle is the primordial structure of the metanephric nephron epithelium, and is formed by the condensation of mesenchymal cells.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-04-01T03:28:00Z					biological_process											owl:Class	
GO:1990922	biolink:NamedThing	hepatic stellate cell proliferation	The multiplication or reproduction of hepatic stellate cells, resulting in the expansion of a hepatic stellate cell population. Hepatic stellate cells are found in the perisinusoidal space of the liver, and are capable of multiple roles including storage of retinol, presentation of antigen to T cells (including CD1d-restricted NKT cells), and upon activation, production of extracellular matrix components. This cell type comprises approximately 8-15% of total cells in the liver.	tmpzr1t_l9r_go_relaxed.owl	Ito cell proliferation|hepatic perisinusoidal cell proliferation|perisinusoidal cell proliferation							sl	2016-01-13T23:12:57Z					biological_process											owl:Class	
GO:0070945	biolink:NamedThing	neutrophil-mediated killing of gram-negative bacterium	The directed killing of a gram-negative bacterium by a neutrophil.	tmpzr1t_l9r_go_relaxed.owl	neutrophil mediated killing of gram-negative bacterium							mah	2009-10-01T01:59:12Z					biological_process											owl:Class	
GO:0046854	biolink:NamedThing	phosphatidylinositol phosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of phosphatidylinositol phosphate.	tmpzr1t_l9r_go_relaxed.owl	phosphatidylinositol phosphorylation|PIP biosynthesis|phosphatidylinositol phosphate biosynthesis|phosphatidylinositol phosphate phosphorylation|phosphoinositide phosphorylation|PtdInsP biosynthesis	https://github.com/geneontology/go-ontology/issues/14184										GO:0046837		biological_process											owl:Class	
GO:0072108	biolink:NamedThing	positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis	Any process that increases the rate, frequency or extent of the transition where a mesenchymal cell establishes apical/basolateral polarity, forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the metanephros.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-02-12T02:45:57Z					biological_process											owl:Class	
GO:0044226	biolink:NamedThing	basal pole of neuron	Portion of a neuron cell soma closest to the point where the basilar dendrite emerges.	tmpzr1t_l9r_go_relaxed.owl					NIF_Subcellular:sao1186862860			jl	2009-11-13T04:32:17Z					cellular_component											owl:Class	
GO:2000540	biolink:NamedThing	negative regulation of protein geranylgeranylation	Any process that stops, prevents or reduces the frequency, rate or extent of protein geranylgeranylation.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of C-terminal protein geranylgeranylation|negative regulation of protein amino acid geranylgeranylation							tb	2011-03-29T06:23:11Z					biological_process											owl:Class	
GO:0034101	biolink:NamedThing	erythrocyte homeostasis	Any process of regulating the production and elimination of erythrocytes within an organism.	tmpzr1t_l9r_go_relaxed.owl	RBC homeostasis|red blood cell homeostasis													biological_process											owl:Class	
GO:0044351	biolink:NamedThing	macropinocytosis	An endocytosis process that results in the uptake of liquid material by cells from their external environment by the 'ruffling' of the cell membrane to form heterogeneously sized intracellular vesicles called macropinosomes, which can be up to 5 micrometers in size.	tmpzr1t_l9r_go_relaxed.owl	clathrin-independent pinocytosis|single-organism macropinocytosis							jl	2011-08-11T10:26:42Z			GO:1902538		biological_process											owl:Class	
GO:0072579	biolink:NamedThing	glycine receptor clustering	The receptor clustering process in which glycine receptors are localized to distinct domains in the cell membrane.	tmpzr1t_l9r_go_relaxed.owl								mah	2011-02-03T01:47:40Z					biological_process											owl:Class	
GO:1900970	biolink:NamedThing	positive regulation of sarcinapterin metabolic process	Any process that activates or increases the frequency, rate or extent of sarcinapterin metabolic process.	tmpzr1t_l9r_go_relaxed.owl	up regulation of sarcinapterin metabolic process|activation of sarcinapterin metabolism|up-regulation of sarcinapterin metabolism|up-regulation of sarcinapterin metabolic process|up regulation of sarcinapterin metabolism|upregulation of sarcinapterin metabolism|activation of sarcinapterin metabolic process|upregulation of sarcinapterin metabolic process|positive regulation of sarcinapterin metabolism							tt	2012-06-14T03:58:43Z					biological_process											owl:Class	
GO:0061426	biolink:NamedThing	positive regulation of sulfite transport by positive regulation of transcription from RNA polymerase II promoter	Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter and activates or increases the frequency, rate or extent of sulfite transport.	tmpzr1t_l9r_go_relaxed.owl								dph	2012-02-02T01:21:46Z					biological_process											owl:Class	
GO:0032590	biolink:NamedThing	dendrite membrane	The portion of the plasma membrane surrounding a dendrite.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0005652	biolink:NamedThing	nuclear lamina	The fibrous, electron-dense layer lying on the nucleoplasmic side of the inner membrane of a cell nucleus, composed of lamin filaments. The polypeptides of the lamina are thought to be concerned in the dissolution of the nuclear envelope and its re-formation during mitosis. The lamina is composed of lamin A and lamin C filaments cross-linked into an orthogonal lattice, which is attached via lamin B to the inner nuclear membrane through interactions with a lamin B receptor, an IFAP, in the membrane.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Nuclear_lamina|NIF_Subcellular:sao1455996588									cellular_component											owl:Class	
GO:0034399	biolink:NamedThing	nuclear periphery	The portion of the nuclear lumen proximal to the inner nuclear membrane.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:2000353	biolink:NamedThing	positive regulation of endothelial cell apoptotic process	Any process that activates or increases the frequency, rate or extent of endothelial cell apoptotic process.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of endothelial cell programmed cell death by apoptosis|positive regulation of programmed cell death of endothelial cells by apoptosis|positive regulation of apoptosis of endothelial cells|positive regulation of programmed cell death, endothelial cells|positive regulation of endothelial cell apoptosis|positive regulation of killing of endothelial cells							mah	2011-02-03T10:43:23Z					biological_process											owl:Class	
GO:2001265	biolink:NamedThing	positive regulation of C-C chemokine binding	Any process that activates or increases the frequency, rate or extent of C-C chemokine binding.	tmpzr1t_l9r_go_relaxed.owl								yaf	2011-12-09T01:14:07Z					biological_process											owl:Class	
GO:1901634	biolink:NamedThing	positive regulation of synaptic vesicle membrane organization	Any process that activates or increases the frequency, rate or extent of synaptic vesicle membrane organization.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of synaptic vesicle membrane organization and biogenesis|up-regulation of synaptic vesicle membrane organisation|activation of synaptic vesicle membrane organisation|up regulation of synaptic vesicle membrane organisation|positive regulation of synaptic vesicle membrane organisation|upregulation of synaptic vesicle membrane organization|up regulation of synaptic vesicle membrane organization|upregulation of SLMV biogenesis|activation of synaptic vesicle membrane organization and biogenesis|upregulation of synaptic vesicle membrane organisation|up regulation of synaptic vesicle membrane organization and biogenesis|upregulation of synaptic vesicle membrane organization and biogenesis|up regulation of SLMV biogenesis|positive regulation of synaptic vesicle membrane organization and biogenesis|up-regulation of synaptic vesicle membrane organization|activation of SLMV biogenesis|up-regulation of SLMV biogenesis|positive regulation of SLMV biogenesis|activation of synaptic vesicle membrane organization							ans	2012-11-15T11:40:59Z					biological_process											owl:Class	
GO:0048499	biolink:NamedThing	synaptic vesicle membrane organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the membrane surrounding a synaptic vesicle.	tmpzr1t_l9r_go_relaxed.owl	synaptic vesicle membrane organization and biogenesis|SLMV biogenesis|synaptic vesicle membrane organisation													biological_process											owl:Class	
GO:0043619	biolink:NamedThing	regulation of transcription from RNA polymerase II promoter in response to oxidative stress	Modulation of the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is under oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0072027	biolink:NamedThing	connecting tubule development	The process whose specific outcome is the progression of the connecting tubule over time, from its formation to the mature structure. The connecting tubule is a tubular segment of the nephron; it connects the distal convoluted tubule to the collecting duct.	tmpzr1t_l9r_go_relaxed.owl	connecting duct development							mah	2010-01-25T02:42:05Z					biological_process											owl:Class	
GO:0060461	biolink:NamedThing	right lung morphogenesis	The process in which anatomical structures of the right lung are generated and organized.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0060458	biolink:NamedThing	right lung development	The biological process whose specific outcome is the progression of a right lung from an initial condition to its mature state. This process begins with the formation of the right lung and ends with the mature structure. The right lung is the lung which is on the right side of the anterior posterior axis looking from a dorsal to ventral aspect.	tmpzr1t_l9r_go_relaxed.owl	right pulmonary development													biological_process											owl:Class	
GO:0043669	biolink:NamedThing	ectexine	The outer part of the exine, which stains positively with basic fuchsin in optical microscopy and has higher electron density in conventionally prepared TEM sections.	tmpzr1t_l9r_go_relaxed.owl						Note that ectexine is distinguished on staining properties; compare with 'sexine ; GO:0043673'. See also 'endexine ; GO:0043671'.								cellular_component											owl:Class	
GO:0010479	biolink:NamedThing	stele development	The process whose specific outcome is the progression of the stele over time, from its formation to the mature structure. The stele is the central column of primary vascular tissue in the root and any tissue that it surrounds.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0015133	biolink:NamedThing	uronic acid transmembrane transporter activity	Enables the transfer of uronic acid from one side of a membrane to the other. Uronic acids are any monocarboxylic acid formally derived by oxidizing to a carboxyl group the terminal hydroxymethylene group of either an aldose with four or more carbon atoms in the molecule, or of any glycoside derived from such an aldose.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0021681	biolink:NamedThing	cerebellar granular layer development	The process whose specific outcome is the progression of the cerebellar granule layer over time, from its formation to the mature structure. The granular layer is the innermost layer of the cerebellar cortex. This layer contains densely packed small neurons, mostly granule cells. Some Golgi cells are found at the outer border. Granule neurons send parallel fibers to the upper molecular layer, where they synapse with Purkinje cell dendrites. Mossy fibers from the pontine nuclei in the white matter synapse with granule cell axons, Golgi cell axons and unipolar brush interneuron axons at cerebellar glomeruli in the granule cell layer.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0060088	biolink:NamedThing	auditory receptor cell stereocilium organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a stereocilium. A stereocilium is an actin-based protrusion from the apical surface of auditory hair cells.	tmpzr1t_l9r_go_relaxed.owl	auditory receptor cell stereocilium organisation|auditory receptor cell stereocilium organization and biogenesis													biological_process											owl:Class	
GO:0002093	biolink:NamedThing	auditory receptor cell morphogenesis	Any process that alters the size or shape of an auditory receptor cell.	tmpzr1t_l9r_go_relaxed.owl	hair cell morphogenesis													biological_process											owl:Class	
GO:0061554	biolink:NamedThing	ganglion formation	The process that gives rise to ganglion. This process pertains to the initial formation of a structure from unspecified parts.	tmpzr1t_l9r_go_relaxed.owl	ganglia formation							dph	2013-07-10T08:51:50Z					biological_process											owl:Class	
GO:0015777	biolink:NamedThing	teichoic acid transport	The directed movement of teichoic acid into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Teichoic acid is any polymer occurring in the cell wall, membrane or capsule of Gram-positive bacteria and containing chains of glycerol phosphate or ribitol phosphate residues.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0006614	biolink:NamedThing	SRP-dependent cotranslational protein targeting to membrane	The targeting of proteins to a membrane that occurs during translation and is dependent upon two key components, the signal-recognition particle (SRP) and the SRP receptor. SRP is a cytosolic particle that transiently binds to the endoplasmic reticulum (ER) signal sequence in a nascent protein, to the large ribosomal unit, and to the SRP receptor in the ER membrane.	tmpzr1t_l9r_go_relaxed.owl	ER translocation|SRP-dependent cotranslational protein-membrane targeting|SRP-dependent cotranslational membrane targeting													biological_process											owl:Class	
GO:0048734	biolink:NamedThing	proboscis morphogenesis	The process in which the anatomical structures of the proboscis are generated and organized. The proboscis is the trunk-like extension of the mouthparts on the adult head.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0003317	biolink:NamedThing	cardioblast cell midline fusion	The attachment of cardiac progenitor cells to one another that contributes to the formation of the heart rudiment.	tmpzr1t_l9r_go_relaxed.owl	cardiac progenitor cell midline fusion							dph	2009-10-27T09:08:57Z					biological_process											owl:Class	
GO:0003315	biolink:NamedThing	heart rudiment formation	The developmental process pertaining to the initial formation of the heart rudiment.	tmpzr1t_l9r_go_relaxed.owl	heart cone formation							dph	2009-10-27T08:43:37Z					biological_process											owl:Class	
GO:0042774	biolink:NamedThing	plasma membrane ATP synthesis coupled electron transport	The transfer of electrons through a series of electron donors and acceptors, generating energy that is ultimately used for synthesis of ATP in the plasma membrane.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1904331	biolink:NamedThing	regulation of error-prone translesion synthesis	Any process that modulates the frequency, rate or extent of error-prone translesion synthesis.	tmpzr1t_l9r_go_relaxed.owl	regulation of mutagenic postreplication DNA repair|regulation of mutagenic PRR|regulation of error-prone postreplication DNA repair							kmv	2015-06-11T16:24:47Z					biological_process											owl:Class	
GO:0071927	biolink:NamedThing	octopamine signaling pathway	The series of molecular signals generated as a consequence of octopamine binding to a cell surface receptor.	tmpzr1t_l9r_go_relaxed.owl	octopamine signalling pathway							mah	2010-09-28T01:18:57Z					biological_process											owl:Class	
GO:1905111	biolink:NamedThing	positive regulation of pulmonary blood vessel remodeling	Any process that activates or increases the frequency, rate or extent of pulmonary blood vessel remodeling.	tmpzr1t_l9r_go_relaxed.owl	activation of pulmonary blood vessel remodeling|up regulation of pulmonary blood vessel remodeling|upregulation of pulmonary blood vessel remodeling|up-regulation of pulmonary blood vessel remodeling							bc	2016-04-06T13:07:42Z					biological_process											owl:Class	
GO:0101010	biolink:NamedThing	pulmonary blood vessel remodeling	The reorganization or renovation of existing pulmonary blood vessels.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0004308	biolink:NamedThing	exo-alpha-sialidase activity	Catalysis of the hydrolysis of alpha-(2->3)-, alpha-(2->6)-, alpha-(2->8)-glycosidic linkages of terminal sialic residues in oligosaccharides, glycoproteins, glycolipids, colominic acid and synthetic substrates.	tmpzr1t_l9r_go_relaxed.owl	alpha-neuraminidase activity|acetylneuraminidase activity|sialidase activity|neuraminidase activity|acetylneuraminyl hydrolase activity|N-acylneuraminate glycohydrolase activity				MetaCyc:3.2.1.18-RXN|Reactome:R-HSA-1605723|Reactome:R-HSA-1605768|Reactome:R-HSA-4341669|EC:3.2.1.18|Reactome:R-HSA-168870|Reactome:R-HSA-4085029|Reactome:R-HSA-4084999|Reactome:R-HSA-9638120|Reactome:R-HSA-4084994|Reactome:R-HSA-1605724									molecular_function											owl:Class	
GO:0010879	biolink:NamedThing	cholesterol transport involved in cholesterol storage	The directed movement of cholesterol into cells that is part of their accumulation and maintenance.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0010878	biolink:NamedThing	cholesterol storage	The accumulation and maintenance in cells or tissues of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.	tmpzr1t_l9r_go_relaxed.owl	sequestration of cholesterol|cholesterol sequestration													biological_process											owl:Class	
GO:1902569	biolink:NamedThing	negative regulation of activation of Janus kinase activity	Any process that stops, prevents or reduces the frequency, rate or extent of activation of JAK (Janus Activated Kinase) kinase activity.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of tyrosine phosphorylation of JAK1 protein|down regulation of tyrosine phosphorylation of JAK1 protein|negative regulation of tyrosine phosphorylation of JAK2 protein|down-regulation of activation of JAK1 kinase activity|downregulation of activation of JAK1 kinase activity|down-regulation of activation of JAK2 protein|negative regulation of tyrosine phosphorylation of JAK1 protein|inhibition of activation of JAK2 kinase activity|downregulation of tyrosine phosphorylation of JAK1 protein|inhibition of activation of JAK2 protein|downregulation of activation of JAK2 kinase activity|negative regulation of activation of JAK1 protein|inhibition of tyrosine phosphorylation of JAK2 protein|down regulation of activation of JAK2 kinase activity|inhibition of activation of JAK1 protein|downregulation of activation of JAK1 protein|down regulation of activation of JAK1 protein|down-regulation of tyrosine phosphorylation of JAK2 protein|down-regulation of activation of JAK1 protein|down regulation of activation of JAK2 protein|down-regulation of activation of JAK2 kinase activity|down regulation of activation of JAK1 kinase activity|negative regulation of activation of JAK2 protein|down regulation of tyrosine phosphorylation of JAK2 protein|negative regulation of activation of JAK2 kinase activity|downregulation of tyrosine phosphorylation of JAK2 protein|inhibition of activation of JAK1 kinase activity|inhibition of tyrosine phosphorylation of JAK1 protein							ecu	2013-12-10T16:13:20Z					biological_process											owl:Class	
GO:2000337	biolink:NamedThing	positive regulation of endothelial microparticle formation	Any process that activates or increases the frequency, rate or extent of endothelial microparticle formation.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of endothelial microparticle generation|positive regulation of endothelial microparticle release							mah	2011-01-31T11:20:38Z					biological_process											owl:Class	
GO:0001739	biolink:NamedThing	sex chromatin	Chromatin that is part of a sex chromosome.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0036464	biolink:NamedThing	cytoplasmic ribonucleoprotein granule	A ribonucleoprotein granule located in the cytoplasm.	tmpzr1t_l9r_go_relaxed.owl	Staufen granule							bf	2014-06-18T09:44:44Z					cellular_component											owl:Class	
GO:0042921	biolink:NamedThing	glucocorticoid receptor signaling pathway	Any series of molecular signals generated as a consequence of a glucocorticoid binding to its receptor.	tmpzr1t_l9r_go_relaxed.owl	glucocorticoid receptor signalling pathway													biological_process											owl:Class	
GO:0042541	biolink:NamedThing	hemoglobin biosynthetic process	The chemical reactions and pathways resulting in the formation of hemoglobin, an oxygen carrying, conjugated protein containing four heme groups and globin.	tmpzr1t_l9r_go_relaxed.owl	hemoglobin anabolism|haemoglobin biosynthesis|hemoglobin biosynthesis|hemoglobin formation|hemoglobin synthesis|haemoglobin biosynthetic process													biological_process											owl:Class	
GO:0048270	biolink:NamedThing	methionine adenosyltransferase regulator activity	Binds to and modulates the activity of methionine adenosyltransferase.	tmpzr1t_l9r_go_relaxed.owl	MAT regulator activity					See also the molecular function term 'methionine adenosyltransferase activity ; GO:0004478'.								molecular_function											owl:Class	
GO:0004478	biolink:NamedThing	methionine adenosyltransferase activity	Catalysis of the reaction: ATP + L-methionine + H2O = phosphate + diphosphate + S-adenosyl-L-methionine.	tmpzr1t_l9r_go_relaxed.owl	adenosylmethionine synthetase activity|AdoMet synthetase activity|S-adenosylmethionine synthase activity|ATP-methionine adenosyltransferase activity|ATP:L-methionine S-adenosyltransferase activity|S-adenosyl-L-methionine synthetase activity|S-adenosylmethionine synthetase activity|methionine-activating enzyme|methionine S-adenosyltransferase activity				RHEA:21080|Reactome:R-HSA-5603114|EC:2.5.1.6|Reactome:R-HSA-5603087|Reactome:R-HSA-174391|MetaCyc:S-ADENMETSYN-RXN									molecular_function											owl:Class	
GO:0008363	biolink:NamedThing	larval chitin-based cuticle development	Synthesis and deposition of a chitin-based larval cuticle. The insect larval cuticle is a secretion from epidermal cells that is shed at each molt. An example of this is found in Drosophila melanogaster.	tmpzr1t_l9r_go_relaxed.owl	larval cuticle biosynthetic process|larval cuticle formation|larval cuticle anabolism|larval cuticle synthesis													biological_process											owl:Class	
GO:0039012	biolink:NamedThing	pronephric sinus development	The process whose specific outcome is the progression of the pronephric sinus over time, from its formation to the mature structure. The pronephric sinus is an ill-defined capillary network that lies between the pronephric tubules.	tmpzr1t_l9r_go_relaxed.owl								bf	2010-07-02T09:55:23Z					biological_process											owl:Class	
GO:2001194	biolink:NamedThing	regulation of lysine biosynthetic process via alpha-aminoadipate and saccharopine	Any process that modulates the frequency, rate or extent of lysine biosynthetic process via alpha-aminoadipate and saccharopine.	tmpzr1t_l9r_go_relaxed.owl	regulation of lysine biosynthesis via aminoadipic acid and saccharopine|regulation of lysine biosynthetic process via aminoadipic acid and saccharopine							mcc	2011-11-03T07:57:11Z					biological_process											owl:Class	
GO:0051975	biolink:NamedThing	lysine biosynthetic process via alpha-aminoadipate and saccharopine	The chemical reactions and pathways resulting in the formation of lysine via the intermediates alpha-aminoadipic acid and saccharopine. This pathway is used by yeast and fungi to synthesize the essential amino acid L-lysine, and pathway intermediates are often incorporated into secondary metabolic processes. The pathway proceeds as follows: alpha-ketoglutarate is converted to homocitrate, which is metabolized to 3-carboxyhex-2-enedioate and then homoisocitrate. This is then decarboxylated to form alpha-ketoadipate, which is then converted to alpha-aminoadipate. This is then reduced to form alpha-aminoadipate 6-semialdehyde, which is metabolized to saccharopine and finally L-lysine.	tmpzr1t_l9r_go_relaxed.owl	lysine biosynthesis via aminoadipic acid and saccharopine|lysine biosynthetic process via aminoadipic acid and saccharopine				MetaCyc:LYSINE-AMINOAD-PWY									biological_process											owl:Class	
GO:0035298	biolink:NamedThing	regulation of Malpighian tubule size	Ensuring that a Malpighian tubule is the correct length and diameter.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0098814	biolink:NamedThing	spontaneous synaptic transmission	The low level of synaptic transmission that occurs via spontaneous neurotransmitter release into the synaptic cleft in the absence of a presynaptic action potential.	tmpzr1t_l9r_go_relaxed.owl	basal synaptic transmission					This is typically measured via detection of mini excitatory post-synaptic currents (mEPSCs).								biological_process											owl:Class	
GO:0001772	biolink:NamedThing	immunological synapse	An area of close contact between a lymphocyte (T-, B-, or natural killer cell) and a target cell formed through the clustering of particular signaling and adhesion molecules and their associated membrane rafts on both the lymphocyte and the target cell and facilitating activation of the lymphocyte, transfer of membrane from the target cell to the lymphocyte, and in some situations killing of the target cell through release of secretory granules and/or death-pathway ligand-receptor interaction.	tmpzr1t_l9r_go_relaxed.owl	c-SMAC|supramolecular activation cluster				Wikipedia:Immunological_synapse									cellular_component											owl:Class	
GO:1904126	biolink:NamedThing	convergent extension involved in notochord morphogenesis	Any convergent extension that is involved in notochord morphogenesis.	tmpzr1t_l9r_go_relaxed.owl								dph	2015-04-10T21:12:57Z					biological_process											owl:Class	
GO:0140622	biolink:NamedThing	ER-to-endosome phospholipid transfer complex	Lipid transfer complex that is responsible for the non-vesicular transport of phospholipids, such as phosphatidylserine, from the endoplasmic reticulum to the endosome. It resides in the endosomal (acceptor) membrane and binds to specific lipids on the donor membrane at the ER-endosome contact site.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/15338						pg	2021-03-10T11:27:24Z					cellular_component											owl:Class	
GO:0060929	biolink:NamedThing	atrioventricular node cell fate commitment	The commitment of cells to atrioventricular (AV) node cell fates and their capacity to differentiate into AV node cells.	tmpzr1t_l9r_go_relaxed.owl	AV node cell fate commitment							dph	2009-09-29T12:01:24Z					biological_process											owl:Class	
GO:0060922	biolink:NamedThing	atrioventricular node cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of an atrioventricular (AV) node cell. AV node cells are pacemaker cells that are found in the atrioventricular node.	tmpzr1t_l9r_go_relaxed.owl	AV node cell differentiation							dph	2009-09-29T11:07:06Z					biological_process											owl:Class	
GO:1904457	biolink:NamedThing	positive regulation of neuronal action potential	Any process that activates or increases the frequency, rate or extent of neuronal action potential.	tmpzr1t_l9r_go_relaxed.owl	up regulation of neuronal action potential|activation of generation of action potential|up-regulation of generation of action potential|up-regulation of neuronal action potential|activation of neuronal action potential|upregulation of neuronal action potential|positive regulation of generation of action potential|up regulation of generation of action potential|upregulation of generation of action potential							sl	2015-07-09T18:02:46Z					biological_process											owl:Class	
GO:0072536	biolink:NamedThing	interleukin-23 receptor complex	A protein complex that binds interleukin-23 and that consists of, at a minimum, a dimeric interleukin and its two receptor subunits as well as optional additional kinase subunits.	tmpzr1t_l9r_go_relaxed.owl	IL-23 receptor complex							mah	2011-01-14T02:51:14Z					cellular_component											owl:Class	
GO:0031110	biolink:NamedThing	regulation of microtubule polymerization or depolymerization	Any process that modulates the frequency, rate or extent of microtubule polymerization or depolymerization by the addition or removal of tubulin heterodimers from a microtubule.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0031109	biolink:NamedThing	microtubule polymerization or depolymerization	Assembly or disassembly of microtubules by the addition or removal of tubulin heterodimers from a microtubule.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0045506	biolink:NamedThing	interleukin-24 receptor activity	Combining with interleukin-24 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	IL-24R|IL-24 receptor activity													molecular_function											owl:Class	
GO:0045510	biolink:NamedThing	interleukin-24 binding	Binding to interleukin-24.	tmpzr1t_l9r_go_relaxed.owl	IL-24 binding													molecular_function											owl:Class	
GO:1990117	biolink:NamedThing	B cell receptor apoptotic signaling pathway	An extrinsic apoptotic signaling pathway initiated by the cross-linking of an antigen receptor on a B cell.	tmpzr1t_l9r_go_relaxed.owl	B cell receptor extrinsic apoptotic signaling pathway|extrinsic apoptotic signaling pathway via BCR|extrinsic apoptotic signaling pathway via B cell antigen receptor							pr	2013-06-06T15:15:17Z					biological_process											owl:Class	
GO:1904502	biolink:NamedThing	regulation of lipophagy	Any process that modulates the frequency, rate or extent of lipophagy.	tmpzr1t_l9r_go_relaxed.owl								dph	2015-07-24T11:37:12Z					biological_process											owl:Class	
GO:1990045	biolink:NamedThing	sclerotium development	The process whose specific outcome is the progression of the sclerotium over time, from its formation to the mature structure. A sclerotium is a mycelial resting body, resistant to adverse environmental conditions.	tmpzr1t_l9r_go_relaxed.owl								pr	2013-02-15T15:30:00Z					biological_process											owl:Class	
GO:0004924	biolink:NamedThing	oncostatin-M receptor activity	Combining with oncostatin-M and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0005003	biolink:NamedThing	ephrin receptor activity	Combining with an ephrin to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	Eph receptor activity													molecular_function											owl:Class	
GO:0048013	biolink:NamedThing	ephrin receptor signaling pathway	The series of molecular signals generated as a consequence of an ephrin receptor binding to an ephrin.	tmpzr1t_l9r_go_relaxed.owl	Eph receptor signaling pathway|Eph receptor signalling pathway													biological_process											owl:Class	
GO:0004963	biolink:NamedThing	follicle-stimulating hormone receptor activity	Combining with follicle-stimulating hormone to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	FSH receptor activity|follicle stimulating hormone receptor activity													molecular_function											owl:Class	
GO:0110107	biolink:NamedThing	regulation of imaginal disc-derived wing vein specification	Any process that modulates the frequency, rate or extent of imaginal disc-derived wing vein specification.	tmpzr1t_l9r_go_relaxed.owl								kmv	2018-07-05T13:44:08Z					biological_process											owl:Class	
GO:0007474	biolink:NamedThing	imaginal disc-derived wing vein specification	The regionalization process in which the area of a imaginal disc-derived wing that will form a wing vein is specified.	tmpzr1t_l9r_go_relaxed.owl	wing vein specification													biological_process											owl:Class	
GO:0045660	biolink:NamedThing	positive regulation of neutrophil differentiation	Any process that activates or increases the frequency, rate or extent of neutrophil differentiation.	tmpzr1t_l9r_go_relaxed.owl	activation of neutrophil differentiation|upregulation of neutrophil differentiation|stimulation of neutrophil differentiation|up-regulation of neutrophil differentiation|up regulation of neutrophil differentiation													biological_process											owl:Class	
GO:0030223	biolink:NamedThing	neutrophil differentiation	The process in which a myeloid precursor cell acquires the specialized features of a neutrophil.	tmpzr1t_l9r_go_relaxed.owl	neutrophil cell differentiation|neutrophil granulocytopoiesis|neutrophil granulocyte differentiation													biological_process											owl:Class	
GO:0032203	biolink:NamedThing	telomere formation via telomerase	A cellular process that results in the formation of a telomere at a non-telomeric double-stranded DNA end that involves the activity of a telomerase enzyme.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1905324	biolink:NamedThing	telomere-telomerase complex assembly	The aggregation, arrangement and bonding together of a set of components to form a telomere-telomerase complex.	tmpzr1t_l9r_go_relaxed.owl	telomere-telomerase complex formation							mah	2016-07-18T10:38:22Z					biological_process											owl:Class	
GO:0035475	biolink:NamedThing	angioblast cell migration involved in selective angioblast sprouting	The directional migration of angioblast cells as part of selective angioblast sprouting, which results in angioblast segregation into arterial and venous populations.	tmpzr1t_l9r_go_relaxed.owl								bf	2010-04-23T10:04:30Z					biological_process											owl:Class	
GO:0002191	biolink:NamedThing	cap-dependent translational initiation	The process where the cap structure, composed of a 7- methylguanosine (m7G) group and associated cap-binding proteins, located at the 5' end of an mRNA molecule, which serves as a molecular tag that marks the spot where the 40S ribosomal subunit, is recruited and will then scan in a 5' to 3' direction until an AUG codon is encountered in an appropriate sequence context to initiate mRNA translation.	tmpzr1t_l9r_go_relaxed.owl								hjd	2011-08-11T02:20:24Z					biological_process											owl:Class	
GO:2000075	biolink:NamedThing	negative regulation of cytokinesis, site selection	Any process that stops, prevents, or reduces the frequency, rate or extent of site selection that occurs as part of cytokinesis.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of site selection involved in cell cycle cytokinesis							tb	2010-08-27T11:19:56Z					biological_process											owl:Class	
GO:0071481	biolink:NamedThing	cellular response to X-ray	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of X-ray radiation. An X-ray is a form of electromagnetic radiation with a wavelength in the range of 10 nanometers to 100 picometers (corresponding to frequencies in the range 30 PHz to 3 EHz).	tmpzr1t_l9r_go_relaxed.owl	cellular response to X-ray radiation stimulus							mah	2009-12-18T02:00:59Z					biological_process											owl:Class	
GO:0042665	biolink:NamedThing	regulation of ectodermal cell fate specification	Any process that mediates the specification of a cell into an ectoderm cell.	tmpzr1t_l9r_go_relaxed.owl	regulation of ectoderm cell fate specification													biological_process											owl:Class	
GO:0001715	biolink:NamedThing	ectodermal cell fate specification	The cell fate determination process that results in a cell becoming becomes capable of differentiating autonomously into an ectoderm cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.	tmpzr1t_l9r_go_relaxed.owl	ectoderm cell fate specification													biological_process											owl:Class	
GO:1903997	biolink:NamedThing	positive regulation of non-membrane spanning protein tyrosine kinase activity	Any process that activates or increases the frequency, rate or extent of non-membrane spanning protein tyrosine kinase activity.	tmpzr1t_l9r_go_relaxed.owl	activation of Bruton's tyrosine kinase activity|positive regulation of ATP:protein-L-tyrosine O-phosphotransferase (non-specific) activity|up regulation of ATP:protein-L-tyrosine O-phosphotransferase (non-specific) activity|positive regulation of p60c-src protein tyrosine kinase activity|activation of janus kinase 1 activity|activation of non-specific protein-tyrosine kinase activity|activation of janus kinase 3 activity|activation of non-membrane spanning protein tyrosine kinase activity|positive regulation of non-specific protein-tyrosine kinase activity|up regulation of Bruton's tyrosine kinase activity|upregulation of cytoplasmic protein tyrosine kinase activity|positive regulation of janus kinase 1 activity|upregulation of non-specific protein-tyrosine kinase activity|up-regulation of janus kinase 3 activity|upregulation of Bruton's tyrosine kinase activity|upregulation of non-membrane spanning protein tyrosine kinase activity|activation of p60c-src protein tyrosine kinase activity|upregulation of janus kinase 3 activity|up-regulation of non-specific protein-tyrosine kinase activity|upregulation of janus kinase 2 activity|up regulation of cytoplasmic protein tyrosine kinase activity|up-regulation of cytoplasmic protein tyrosine kinase activity|positive regulation of focal adhesion kinase activity|upregulation of focal adhesion kinase activity|activation of ATP:protein-L-tyrosine O-phosphotransferase (non-specific) activity|up regulation of p60c-src protein tyrosine kinase activity|positive regulation of janus kinase 3 activity|up regulation of non-specific protein-tyrosine kinase activity|up-regulation of p60c-src protein tyrosine kinase activity|up-regulation of focal adhesion kinase activity|up-regulation of ATP:protein-L-tyrosine O-phosphotransferase (non-specific) activity|up regulation of non-membrane spanning protein tyrosine kinase activity|upregulation of ATP:protein-L-tyrosine O-phosphotransferase (non-specific) activity|up-regulation of Bruton's tyrosine kinase activity|up-regulation of non-membrane spanning protein tyrosine kinase activity|activation of cytoplasmic protein tyrosine kinase activity|up regulation of janus kinase 3 activity|activation of focal adhesion kinase activity|positive regulation of Bruton's tyrosine kinase activity|up-regulation of janus kinase 2 activity|activation of janus kinase 2 activity|up regulation of focal adhesion kinase activity|upregulation of p60c-src protein tyrosine kinase activity|up regulation of janus kinase 2 activity|upregulation of janus kinase 1 activity|positive regulation of janus kinase 2 activity|positive regulation of cytoplasmic protein tyrosine kinase activity|up regulation of janus kinase 1 activity|up-regulation of janus kinase 1 activity							nc	2015-03-05T16:34:46Z					biological_process											owl:Class	
GO:0061192	biolink:NamedThing	negative regulation of vacuole fusion, non-autophagic	Any process that decreases the frequency, rate or extent of the fusion of two vacuole membranes to form a single vacuole.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-07-14T09:35:18Z					biological_process											owl:Class	
GO:0042144	biolink:NamedThing	vacuole fusion, non-autophagic	The fusion of two vacuole membranes to form a single vacuole.	tmpzr1t_l9r_go_relaxed.owl	homotypic vacuole fusion (non-autophagic)|vacuole fusion (non-autophagic)|homotypic vacuole fusion|homotypic vacuole fusion, non-autophagic											GO:0042145		biological_process											owl:Class	
GO:0106006	biolink:NamedThing	cytoskeletal protein-membrane anchor activity	The binding activity of a molecule that brings together a cytoskeletal protein or protein complex and a plasma membrane lipid or membrane-associated protein, in order to maintain the localization of the cytoskeleton at a specific cortical membrane location.	tmpzr1t_l9r_go_relaxed.owl	F-BAR domain adaptor|cytoskeletal protein-membrane adaptor activity|membrane-cytoskeletal protein tether activity|cytoskeletal protein membrane adaptor|cytoskeletal protein membrane tether activity|membrane-cytoskeletal protein anchor activity|microtubule cortical anchor activity|BAR domain adaptor|cytoskeletal protein membrane anchor activity	https://github.com/geneontology/go-ontology/issues/19119|https://github.com/geneontology/go-ontology/issues/18281|https://github.com/geneontology/go-ontology/issues/17668						hjd	2017-04-14T15:11:13Z			GO:0140362		molecular_function											owl:Class	
GO:1900491	biolink:NamedThing	regulation of [4Fe-4S] cluster assembly	Any process that modulates the frequency, rate or extent of [4Fe-4S] cluster assembly.	tmpzr1t_l9r_go_relaxed.owl	regulation of 4Fe-4S cluster assembly|regulation of [4Fe-4S] cluster biosynthetic process							tt	2012-05-02T03:48:49Z					biological_process											owl:Class	
GO:0061047	biolink:NamedThing	positive regulation of branching involved in lung morphogenesis	Any process that increases the rate, frequency, or extent of the process in which a highly ordered sequence of patterning events generates the branched structures of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-02-25T10:50:01Z					biological_process											owl:Class	
GO:0034591	biolink:NamedThing	rhoptry lumen	The volume enclosed by the rhoptry membrane.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0020008	biolink:NamedThing	rhoptry	A large, club-shaped secretory organelle that forms part of the apical complex of an apicomplexan parasite, and consists of a bulbous body and a narrow electron-dense neck that extends through the conoid at the apical tip of the parasite. The rhoptry necks serve as ducts through which the contents of the rhoptries are secreted after attachment to the host has been completed and at the commencement of invasion. Rhoptry proteins function in the biogenesis and host organellar association of the parasitophorous vacuole.	tmpzr1t_l9r_go_relaxed.owl	toxoneme|paired organelles				Wikipedia:Rhoptry									cellular_component											owl:Class	
GO:1903394	biolink:NamedThing	protein localization to kinetochore involved in kinetochore assembly	Any protein localization to kinetochore that is involved in kinetochore assembly.	tmpzr1t_l9r_go_relaxed.owl	protein localization to kinetochore involved in centromere/kinetochore complex maturation|condensin localization to kinetochore involved in kinetochore formation|condensin localization to kinetochore involved in centromere and kinetochore complex maturation|protein localisation to kinetochore involved in chromosome-kinetochore attachment|condensin localization to kinetochore involved in centromere/kinetochore complex maturation|protein localization to kinetochore involved in kinetochore formation|protein localisation to kinetochore involved in kinetochore assembly|condensin localization to kinetochore involved in chromosome-kinetochore attachment|condensin localization to kinetochore involved in kinetochore assembly|protein localisation to kinetochore involved in centromere/kinetochore complex maturation|protein localisation to kinetochore involved in kinetochore formation|protein localization to kinetochore involved in centromere and kinetochore complex maturation|protein localisation to kinetochore involved in centromere and kinetochore complex maturation|protein localization to kinetochore involved in chromosome-kinetochore attachment							vw	2014-08-29T13:11:55Z					biological_process											owl:Class	
GO:0051382	biolink:NamedThing	kinetochore assembly	The aggregation, arrangement and bonding together of a set of components to form the kinetochore, a multisubunit complex that is located at the centromeric region of DNA and provides an attachment point for the spindle microtubules.	tmpzr1t_l9r_go_relaxed.owl	centromere and kinetochore complex maturation|kinetochore formation|centromere/kinetochore complex maturation|chromosome-kinetochore attachment											GO:0000069		biological_process											owl:Class	
GO:0032921	biolink:NamedThing	sarcosine oxidase complex	A complex consisting of 4 protein subunits as a heterotetramer, that possesses sarcosine oxidase activity.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0036304	biolink:NamedThing	umbilical cord morphogenesis	The process in which the anatomical structures of the umbilical cord are generated and organized. The umbilical cord is an organ or embryonic origin consisting of the 2 umbilical arteries and the one umbilical vein. The umbilical cord connects the cardiovascular system of the fetus to the mother via the placenta.	tmpzr1t_l9r_go_relaxed.owl								bf	2012-08-08T10:12:11Z					biological_process											owl:Class	
GO:0021547	biolink:NamedThing	midbrain-hindbrain boundary initiation	The regionalization process that gives rise to the midbrain-hindbrain boundary. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate.	tmpzr1t_l9r_go_relaxed.owl	MHB formation|midbrain-hindbrain boundary formation|midbrain-hindbrain boundary biosynthesis|isthmus formation|isthmus biosynthesis|MHB biosynthesis													biological_process											owl:Class	
GO:0048868	biolink:NamedThing	pollen tube development	The process whose specific outcome is the progression of a pollen tube over time, from its initial formation to a mature structure.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0098885	biolink:NamedThing	modification of postsynaptic actin cytoskeleton	Any process that modifies the structure of a postsynaptic actin cytoskeleton.	tmpzr1t_l9r_go_relaxed.owl	postsynaptic actin cytoskeleton remodelling					This class does not cover assembly or disassembly of synapses, only the modification/remodelling of existing ones.								biological_process											owl:Class	
GO:0044024	biolink:NamedThing	histone kinase activity (H2A-S1 specific)	Catalysis of the transfer of a phosphate group to the serine-1 residue of the N-terminal tail of histone H2A.	tmpzr1t_l9r_go_relaxed.owl	histone-serine kinase activity (H2A-S1 specific)|histone serine kinase activity (H2A-S1 specific)													molecular_function											owl:Class	
GO:1905420	biolink:NamedThing	vascular associated smooth muscle cell differentiation involved in phenotypic switching	Any vascular smooth muscle cell differentiation that is involved in phenotypic switching.	tmpzr1t_l9r_go_relaxed.owl	vascular smooth muscle cell differentiation involved in phenotypic switching|vascular associated smooth muscle cell differentiation involved in phenotypic dimorphism|VSMC differentiation involved in phenotypic switching|VSMC differentiation involved in phenotypic dimorphism|vascular smooth muscle cell differentiation involved in phenotypic dimorphism							rph	2016-09-05T12:43:46Z					biological_process											owl:Class	
GO:0033116	biolink:NamedThing	endoplasmic reticulum-Golgi intermediate compartment membrane	The lipid bilayer surrounding any of the compartments of the endoplasmic reticulum (ER)-Golgi intermediate compartment system.	tmpzr1t_l9r_go_relaxed.owl	ER-Golgi intermediate compartment membrane													cellular_component											owl:Class	
GO:0061250	biolink:NamedThing	mesonephric glomerular epithelial cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a mesonephric glomerular epithelial cell. Mesonephric glomerular epithelial cells are specialized epithelial cells that form part of the mesonephric glomerulus; there are two types, mesonephric glomerular parietal epithelial cells and mesonephric glomerular visceral epithelial cells.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-08-30T01:20:03Z					biological_process											owl:Class	
GO:0038014	biolink:NamedThing	negative regulation of insulin receptor signaling pathway by insulin receptor internalization	Any process in which internalization of an insulin receptor stops, prevents, or reduces the frequency, rate or extent of insulin receptor signal transduction. Internalization of insulin in association with its receptor clears insulin from the circulation and is necessary for subsequent insulin dissociation from the receptor and insulin degradation.	tmpzr1t_l9r_go_relaxed.owl	agonist-stimulated insulin receptor internalization|negative regulation of insulin receptor signalling pathway by insulin receptor internalization							bf	2011-06-23T04:08:31Z					biological_process											owl:Class	
GO:1902119	biolink:NamedThing	regulation of meiotic spindle elongation	Any process that modulates the frequency, rate or extent of meiotic spindle elongation.	tmpzr1t_l9r_go_relaxed.owl	regulation of spindle elongation during meiosis							al	2013-05-15T15:15:48Z					biological_process											owl:Class	
GO:1903749	biolink:NamedThing	positive regulation of establishment of protein localization to mitochondrion	Any process that activates or increases the frequency, rate or extent of establishment of protein localization to mitochondrion.	tmpzr1t_l9r_go_relaxed.owl	up regulation of establishment of protein localisation to mitochondrion|positive regulation of establishment of protein localisation to mitochondrion|up regulation of establishment of protein localization to mitochondrion|up-regulation of establishment of protein localization in mitochondrion|activation of establishment of protein localization to mitochondrion|up-regulation of establishment of protein localization to mitochondrion|upregulation of establishment of protein localization to mitochondrion|activation of establishment of protein localization in mitochondrion|upregulation of establishment of protein localisation to mitochondrion|up regulation of establishment of protein localization in mitochondrion|positive regulation of establishment of protein localization in mitochondrion|upregulation of establishment of protein localization in mitochondrion|activation of establishment of protein localisation to mitochondrion|up-regulation of establishment of protein localisation to mitochondrion							krc	2014-12-12T22:18:26Z					biological_process											owl:Class	
GO:0031322	biolink:NamedThing	ascospore-type prospore-specific spindle pole body remodeling	A spindle pole body (SPB) organization process that takes place during the second meiotic division during ascospore formation and results in the structural reorganization of the SPB; includes the recruitment of sporulation-specific proteins to the outer plaque to form the meiotic outer plaque (MOP).	tmpzr1t_l9r_go_relaxed.owl	ascospore-type prospore-specific spindle pole body modification|forespore-specific spindle pole body remodeling|forespore specific spindle pole body remodeling|ascospore-type prospore-specific spindle pole body remodelling|sporulation-specific spindle pole body remodeling|prospore-specific spindle pole body remodeling													biological_process											owl:Class	
GO:0030426	biolink:NamedThing	growth cone	The migrating motile tip of a growing neuron projection, where actin accumulates, and the actin cytoskeleton is the most dynamic.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Growth_cone									cellular_component											owl:Class	
GO:0044602	biolink:NamedThing	protein deadenylylation	The removal of an adenylyl group (adenosine 5'-monophosphate; AMP) from a protein amino acid.	tmpzr1t_l9r_go_relaxed.owl	protein deAMPylation							jl	2012-05-01T04:16:22Z					biological_process											owl:Class	
GO:1903584	biolink:NamedThing	regulation of histone deubiquitination	Any process that modulates the frequency, rate or extent of histone deubiquitination.	tmpzr1t_l9r_go_relaxed.owl	regulation of histone deubiquitinylation|regulation of histone deubiquitylation							lb	2014-11-03T13:47:26Z					biological_process											owl:Class	
GO:0060699	biolink:NamedThing	regulation of endoribonuclease activity	Any process that modulates the rate, frequency or extent of the catalysis of the hydrolysis of ester linkages within ribonucleic acid by creating internal breaks.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-06-08T02:43:10Z					biological_process											owl:Class	
GO:0044289	biolink:NamedThing	mitochondrial inner-outer membrane contact site	Sites of close apposition of the inner and outer mitochondrial membrane.	tmpzr1t_l9r_go_relaxed.owl	contact site|bridge contact site	https://github.com/geneontology/go-ontology/issues/18994						jl	2010-02-04T02:25:11Z			GO:0044285		cellular_component											owl:Class	
GO:0036065	biolink:NamedThing	fucosylation	The covalent attachment of a fucosyl group to an acceptor molecule.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-12-15T11:16:19Z					biological_process											owl:Class	
GO:1904419	biolink:NamedThing	negative regulation of telomeric loop formation	Any process that stops, prevents or reduces the frequency, rate or extent of telomeric loop formation.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of telomeric loop formation|down regulation of t-loop biosynthesis|down regulation of telomeric loop formation|inhibition of t-loop biosynthesis|negative regulation of t-loop biosynthesis|negative regulation of t-loop formation|inhibition of telomeric loop formation|inhibition of t-loop formation|down-regulation of t-loop formation|downregulation of t-loop formation|down regulation of t-loop formation|downregulation of t-loop biosynthesis|down-regulation of t-loop biosynthesis|downregulation of telomeric loop formation							nc	2015-07-01T10:40:29Z					biological_process											owl:Class	
GO:1990760	biolink:NamedThing	osmolarity-sensing cation channel activity	Enables the transmembrane transfer of a cation by a channel that opens when a change in the osmolarity occurs in the extracellular space of the cell in which the cation channel resides.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-06-05T21:58:50Z					molecular_function											owl:Class	
GO:1902318	biolink:NamedThing	synthesis of RNA primer involved in nuclear cell cycle DNA replication	Any synthesis of RNA primer that is involved in nuclear cell cycle DNA replication.	tmpzr1t_l9r_go_relaxed.owl	DNA replication, synthesis of RNA primer involved in DNA replication during S phase|DNA replication, synthesis of RNA primer involved in DNA replication involved in S-phase|replication priming involved in DNA replication involved in S-phase|replication priming involved in DNA replication involved in S phase|replication priming involved in DNA replication during S phase|DNA replication, synthesis of RNA primer involved in DNA replication involved in S phase|replication priming involved in nuclear cell cycle DNA replication							jl	2013-07-23T14:00:33Z					biological_process											owl:Class	
GO:0035502	biolink:NamedThing	metanephric part of ureteric bud development	The development of the portion of the ureteric bud tube that contributes to the morphogenesis of the metanephros.	tmpzr1t_l9r_go_relaxed.owl								bf	2010-04-29T03:22:21Z					biological_process											owl:Class	
GO:0003872	biolink:NamedThing	6-phosphofructokinase activity	Catalysis of the reaction: ATP + D-fructose-6-phosphate = ADP + D-fructose 1,6-bisphosphate.	tmpzr1t_l9r_go_relaxed.owl	fructose 6-phosphate kinase activity|D-fructose-6-phosphate 1-phosphotransferase activity|phosphofructokinase (phosphorylating)|phospho-1,6-fructokinase activity|ATP:D-fructose-6-phosphate 1-phosphotransferase activity|6-phosphofructose 1-kinase activity|6-phosphofructokinase reduction|ATP-dependent phosphofructokinase activity|nucleotide triphosphate-dependent phosphofructokinase activity|fructose 6-phosphokinase activity|phosphofructokinase I activity|PFK|phosphohexokinase activity				Reactome:R-HSA-70467|MetaCyc:6PFRUCTPHOS-RXN|EC:2.7.1.11|RHEA:16109									molecular_function											owl:Class	
GO:1904569	biolink:NamedThing	regulation of selenocysteine incorporation	Any process that modulates the frequency, rate or extent of selenocysteine incorporation.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-08-19T17:26:38Z					biological_process											owl:Class	
GO:0010994	biolink:NamedThing	free ubiquitin chain polymerization	The process of creating free ubiquitin chains, compounds composed of a large number of ubiquitin monomers. These chains are not conjugated to a protein.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-06-03T11:41:03Z					biological_process											owl:Class	
GO:0016230	biolink:NamedThing	sphingomyelin phosphodiesterase activator activity	Increases the activity of the enzyme sphingomyelin phosphodiesterase.	tmpzr1t_l9r_go_relaxed.owl	neutral sphingomyelinase activator													molecular_function											owl:Class	
GO:0021652	biolink:NamedThing	rhombomere 1 formation	The process that gives rise to rhombomere 1. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0021651	biolink:NamedThing	rhombomere 1 morphogenesis	The process in which the anatomical structure of rhombomere 1 is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0050220	biolink:NamedThing	prostaglandin-E synthase activity	Catalysis of the reaction: prostaglandin H(2) = prostaglandin E(2).	tmpzr1t_l9r_go_relaxed.owl	prostaglandin R-prostaglandin E isomerase activity|PGE isomerase activity|endoperoxide isomerase activity|prostaglandin H-E isomerase activity|PGH-PGE isomerase activity|prostaglandin-H2 E-isomerase activity|Prostaglandin-H(2) E-isomerase activity|PGE2 isomerase activity|prostaglandin endoperoxide E isomerase activity|(5Z,13E)-(15S)-9alpha,11alpha-epidioxy-15-hydroxyprosta-5,13-dienoate E-isomerase activity|prostaglandin endoperoxide E2 isomerase activity				MetaCyc:PROSTAGLANDIN-E-SYNTHASE-RXN|Reactome:R-HSA-265295|KEGG_REACTION:R02265|EC:5.3.99.3|RHEA:12893|Reactome:R-HSA-2161660									molecular_function											owl:Class	
GO:2000385	biolink:NamedThing	positive regulation of ectoderm development	Any process that activates or increases the frequency, rate or extent of ectoderm development.	tmpzr1t_l9r_go_relaxed.owl								vk	2011-02-15T03:17:39Z					biological_process											owl:Class	
GO:0010483	biolink:NamedThing	pollen tube reception	Interaction between the pollen tube, part of the male gametophyte, and the ovule, part of the female gametophyte, that results in the arrest of pollen tube growth, rupture of the pollen tube and the release of the sperm cells.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:2000357	biolink:NamedThing	negative regulation of kidney smooth muscle cell differentiation	Any process that stops, prevents or reduces the frequency, rate or extent of kidney smooth muscle cell differentiation.	tmpzr1t_l9r_go_relaxed.owl								yaf	2011-02-03T02:14:28Z					biological_process											owl:Class	
GO:0008586	biolink:NamedThing	imaginal disc-derived wing vein morphogenesis	The process in which anatomical structures of the veins on an imaginal disc-derived wing are generated and organized.	tmpzr1t_l9r_go_relaxed.owl	wing vein morphogenesis													biological_process											owl:Class	
GO:0032424	biolink:NamedThing	negative regulation of mismatch repair	Any process that stops, prevents, or reduces the frequency, rate or extent of mismatch repair.	tmpzr1t_l9r_go_relaxed.owl	downregulation of mismatch repair|down regulation of mismatch repair|down-regulation of mismatch repair|inhibition of mismatch repair													biological_process											owl:Class	
GO:0006298	biolink:NamedThing	mismatch repair	A system for the correction of errors in which an incorrect base, which cannot form hydrogen bonds with the corresponding base in the parent strand, is incorporated into the daughter strand. The mismatch repair system promotes genomic fidelity by repairing base-base mismatches, insertion-deletion loops and heterologies generated during DNA replication and recombination.	tmpzr1t_l9r_go_relaxed.owl	MMR|MutS/MutL/MutH pathway|mismatch repair, MutL-like pathway|long patch mismatch repair system				Wikipedia:DNA_mismatch_repair							GO:0006300		biological_process											owl:Class	
GO:0015877	biolink:NamedThing	biopterin transport	The directed movement of biopterin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Biopterin is a growth factor for certain protozoans and some insects; it is widely distributed in tissues and functions in a reduced form, tetrahydrobiopterin, as a hydroxylation coenzyme.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1901877	biolink:NamedThing	negative regulation of calcium ion binding	Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion binding.	tmpzr1t_l9r_go_relaxed.owl	down regulation of calcium ion storage activity|negative regulation of calcium ion storage activity|downregulation of calcium ion storage activity|down regulation of calcium ion binding|inhibition of calcium ion binding|down-regulation of calcium ion storage activity|inhibition of calcium ion storage activity|down-regulation of calcium ion binding|downregulation of calcium ion binding							rl	2013-02-06T12:38:22Z					biological_process											owl:Class	
GO:0050980	biolink:NamedThing	detection of light stimulus involved in magnetoreception	The series of events involved in magnetoception in which a light stimulus is received and converted into a molecular signal. Downstream processing of the light information in addition to other sensory data allows organisms to perceive the orientation of a magnetic field.	tmpzr1t_l9r_go_relaxed.owl	magnetoreception, sensory detection of light stimulus|sensory transduction of light stimulus during magnetoreception|sensory detection of light stimulus during magnetoreception|magnetoreception, sensory transduction of light stimulus|magnetoreception, detection of light stimulus													biological_process											owl:Class	
GO:0120223	biolink:NamedThing	larynx morphogenesis	The process in which the larynx is generated and organized. The larynx is a continuation of the pharynx that is involved in breathing, sound production, and protecting the trachea against food aspiration.	tmpzr1t_l9r_go_relaxed.owl	laryngeal morphogenesis							krc	2020-02-22T01:42:04Z					biological_process											owl:Class	
GO:0019139	biolink:NamedThing	cytokinin dehydrogenase activity	Catalysis of the reaction: N6-dimethylallyladenine + acceptor + H2O = adenine + 3-methylbut-2-enal + reduced electron acceptor.	tmpzr1t_l9r_go_relaxed.owl	N6-dimethylallyladenine:acceptor oxidoreductase activity|6-N-dimethylallyladenine:acceptor oxidoreductase activity|cytokinin oxidase activity|N6-dimethylallyladenine:(acceptor) oxidoreductase activity				RHEA:13625|EC:1.5.99.12|MetaCyc:PWY-2841|MetaCyc:1.5.99.12-RXN							GO:0046420		molecular_function											owl:Class	
GO:0062235	biolink:NamedThing	axonemal basal plate assembly	The aggregation, arrangement and bonding together of a set of components to form an axonemal basal plate.	tmpzr1t_l9r_go_relaxed.owl	basal plate assembly|axoneme basal plate assembly|axonemal basal plate formation							dph	2020-04-16T12:21:35Z					biological_process											owl:Class	
GO:0043845	biolink:NamedThing	DNA polymerase III, proofreading complex	A subcomplex of DNA polymerase III composed of the epsilon subunit which has proofreading activity, and the theta subunit which enhances the epsilon subunit's proofreading activity.	tmpzr1t_l9r_go_relaxed.owl	DNA polymerase III, proof-reading complex|DNA polymerase III, proofreading subcomplex|DNA polymerase III, proof-reading subcomplex													cellular_component											owl:Class	
GO:0044776	biolink:NamedThing	DNA polymerase III, core complex	The DNA polymerase III core complex consists of the alpha,epsilon and theta subunits and is carries out the polymerase and the 3'-5' exonuclease proofreading activities.	tmpzr1t_l9r_go_relaxed.owl								jl	2013-03-13T14:09:38Z					cellular_component											owl:Class	
GO:0045298	biolink:NamedThing	tubulin complex	A heterodimer of tubulins alpha and beta that constitutes the protomer for microtubule assembly.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0001770	biolink:NamedThing	establishment of natural killer cell polarity	The directed orientation of natural killer cell signaling molecules and associated membrane rafts towards a chemokine gradient or a contact point with a cell displaying natural killer cell activating ligands.	tmpzr1t_l9r_go_relaxed.owl	establishment of NK cell polarity|NK cell polarization|natural killer cell polarization													biological_process											owl:Class	
GO:0009244	biolink:NamedThing	lipopolysaccharide core region biosynthetic process	The chemical reactions and pathways resulting in the formation of the core region of bacterial lipopolysaccharides, which contains ten saccharide residues.	tmpzr1t_l9r_go_relaxed.owl	lipopolysaccharide core region formation|lipopolysaccharide core region synthesis|lipopolysaccharide core region biosynthesis|lipopolysaccharide core region anabolism|LPS core region biosynthetic process													biological_process											owl:Class	
GO:0002681	biolink:NamedThing	somatic recombination of T cell receptor gene segments	The process in which T cell receptor genes are formed through recombination of the germline genetic elements, also known as T cell receptor gene segments.	tmpzr1t_l9r_go_relaxed.owl	somatic recombination of TCR gene segments													biological_process											owl:Class	
GO:2001012	biolink:NamedThing	mesenchymal cell differentiation involved in renal system development	The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesenchymal cells of the renal system as it progresses from its formation to the mature state.	tmpzr1t_l9r_go_relaxed.owl	mesenchymal cell differentiation involved in urinary system development|mesenchymal cell differentiation involved in urinary tract development							yaf	2011-08-09T04:05:14Z					biological_process											owl:Class	
GO:0021830	biolink:NamedThing	interneuron migration from the subpallium to the cortex	The directed movement of interneurons from the subpallium to the cortex during forebrain development.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0045874	biolink:NamedThing	positive regulation of sevenless signaling pathway	Any process that activates or increases the frequency, rate or extent of the sevenless signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	upregulation of sevenless signaling pathway|positive regulation of sevenless signalling pathway|stimulation of sevenless signaling pathway|up regulation of sevenless signaling pathway|activation of sevenless signaling pathway|up-regulation of sevenless signaling pathway|positive regulation of sev signaling pathway													biological_process											owl:Class	
GO:0099139	biolink:NamedThing	cheating during chimeric sorocarp development	Any process during chimeric sorocarp development that increases by which a cell increases the number of spore cells sharing its genotype at the expense of cells of other genotypes.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0032162	biolink:NamedThing	mating projection septin band	A septin band, i.e. a diffuse ring composed of a series of septin bars running parallel to the long axis of the cell, located at the neck of a shmoo (mating projection).	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0070447	biolink:NamedThing	positive regulation of oligodendrocyte progenitor proliferation	Any process that activates or increases the rate or extent of oligodendrocyte progenitor proliferation.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of oligodendrocyte precursor proliferation													biological_process											owl:Class	
GO:0070444	biolink:NamedThing	oligodendrocyte progenitor proliferation	The multiplication or reproduction of oligodendrocyte progenitor cells by cell division, resulting in the expansion of their population. Oligodendrocyte progenitors give rise to oligodendrocytes, which form the insulating myelin sheath of axons in the central nervous system.	tmpzr1t_l9r_go_relaxed.owl	oligodendrocyte precursor proliferation													biological_process											owl:Class	
GO:0032932	biolink:NamedThing	negative regulation of astral microtubule depolymerization	Any process that stops, prevents, or reduces the frequency, rate or extent of the depolymerization of astral microtubules.	tmpzr1t_l9r_go_relaxed.owl	astral microtubule stabilization													biological_process											owl:Class	
GO:0140619	biolink:NamedThing	DNA strand exchange activator activity	Binds to and increases a DNA strand exchange activity.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/20964						pg	2021-02-26T17:56:46Z					molecular_function											owl:Class	
GO:2000421	biolink:NamedThing	positive regulation of eosinophil extravasation	Any process that activates or increases the frequency, rate or extent of eosinophil extravasation.	tmpzr1t_l9r_go_relaxed.owl								mah	2011-02-23T01:47:42Z					biological_process											owl:Class	
GO:0072682	biolink:NamedThing	eosinophil extravasation	The migration of an eosinophil from the blood vessels into the surrounding tissue.	tmpzr1t_l9r_go_relaxed.owl								mah	2011-02-22T04:02:22Z					biological_process											owl:Class	
GO:0003329	biolink:NamedThing	pancreatic PP cell fate commitment	The commitment of a cell to a pancreatic PP cell fate and its capacity to differentiate into a pancreatic PP cell. A pancreatic polypeptide-producing cell is a cell in the pancreas that produces pancreatic polypeptide.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-11-02T08:35:13Z					biological_process											owl:Class	
GO:0003312	biolink:NamedThing	pancreatic PP cell differentiation	The process in which relatively unspecialized cells acquire specialized structural and functional features of a pancreatic polypeptide-producing cell. A pancreatic polypeptide-producing cell is a cell in the pancreas that produces pancreatic polypeptide.	tmpzr1t_l9r_go_relaxed.owl	pancreatic polypeptide-producing cell differentiation							dph	2009-10-26T09:32:32Z					biological_process											owl:Class	
GO:0060799	biolink:NamedThing	transforming growth factor beta receptor signaling pathway involved in endodermal cell fate specification	The series of molecular signals generated as a consequence of a transforming growth factor beta receptor binding to one of its physiological ligands and ultimately resulting in the commitment of an unspecified fate to adopt an endoderm fate.	tmpzr1t_l9r_go_relaxed.owl	transforming growth factor beta receptor signalling pathway involved in endodermal cell fate specification							dph	2009-08-06T11:24:01Z					biological_process											owl:Class	
GO:0001714	biolink:NamedThing	endodermal cell fate specification	The cell fate determination process that results in a cell becoming capable of differentiating autonomously into an endoderm cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.	tmpzr1t_l9r_go_relaxed.owl	endoderm cell fate specification													biological_process											owl:Class	
GO:0006661	biolink:NamedThing	phosphatidylinositol biosynthetic process	The chemical reactions and pathways resulting in the formation of phosphatidylinositol, any glycophospholipid in which the sn-glycerol 3-phosphate residue is esterified to the 1-hydroxyl group of 1D-myo-inositol.	tmpzr1t_l9r_go_relaxed.owl	phosphoinositide biosynthetic process|phosphatidylinositol anabolism|phosphatidylinositol biosynthesis|PtdIns biosynthetic process|PtdIns biosynthesis|phosphoinositide biosynthesis|phosphatidylinositol formation|phosphatidylinositol synthesis											GO:0046489		biological_process											owl:Class	
GO:0061449	biolink:NamedThing	olfactory bulb tufted cell development	The process whose specific outcome is the progression of an olfactory bulb tufted cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.	tmpzr1t_l9r_go_relaxed.owl								dph	2012-05-15T12:30:21Z					biological_process											owl:Class	
GO:1903231	biolink:NamedThing	mRNA binding involved in posttranscriptional gene silencing	Any mRNA binding that is involved in posttranscriptional gene silencing.	tmpzr1t_l9r_go_relaxed.owl	mRNA binding involved in PTGS|mRNA binding involved in quelling|mRNA binding involved in post-transcriptional gene silencing|mRNA binding involved in cosuppression							jl	2014-07-31T10:30:43Z					molecular_function											owl:Class	
GO:0016333	biolink:NamedThing	morphogenesis of follicular epithelium	The process in which the anatomical structures of a follicular epithelium are generated and organized.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0043218	biolink:NamedThing	compact myelin	The portion of the myelin sheath in which layers of cell membrane are tightly juxtaposed, completely excluding cytoplasm. The juxtaposed cytoplasmic surfaces form the major dense line, while the juxtaposed extracellular surfaces form the interperiod line visible in electron micrographs.	tmpzr1t_l9r_go_relaxed.owl	oligodendrocyte compact myelin|Schwann cell compact myelin				NIF_Subcellular:sao1123256993									cellular_component											owl:Class	
GO:0052606	biolink:NamedThing	chlorophyllide a oxygenase activity	Catalysis of the reaction: chlorophyllide a + NADPH + O2 + 2 H+ = 7-hydroxychlorophyllide a + NADP+ + H2O.	tmpzr1t_l9r_go_relaxed.owl	chlorophyllide-a oxygenase activity|chlorophyllide a:oxygen 7-oxidoreductase activity|CAO activity|chlorophyll a oxygenase activity				MetaCyc:RXN-7676|KEGG_REACTION:R08203|RHEA:22676									molecular_function											owl:Class	
GO:0010277	biolink:NamedThing	chlorophyllide a oxygenase [overall] activity	Catalysis of the reactions: chlorophyllide a + O2 + NADPH + H+ = 7-hydroxychlorophyllide a + H2O + NADP+; and 7-hydroxychlorophyllide a + O2 + NADPH + H+ = chlorophyllide b + 2 H2O + NADP+.	tmpzr1t_l9r_go_relaxed.owl	chlorophyll b synthesis activity|CAO activity|chlorophyll-b synthesis activity|chlorophyllide a:oxygen 7-oxidoreduction activity|chlorophyll a oxygenation activity|chlorophyllide-a oxygenation activity				EC:1.14.13.122|RHEA:30359	This is a process composed of two reactions represented by the terms 'GO:0052606 : chlorophyllide a oxygenase activity' and 'GO:0052607 : 7-hydroxy-chlorophyllide a oxygenase activity'.						GO:0046407		molecular_function											owl:Class	
GO:0071960	biolink:NamedThing	maintenance of mitotic sister chromatid cohesion, centromeric	The process in which the association between sister chromatids of a replicated chromosome along the length of the centromeric region is maintained as chromosomes condense, attach to the spindle in a bipolar orientation, and congress to the metaphase plate during a mitotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl	maintenance of sister chromatin cohesion at centromere at mitosis|maintenance of mitotic sister chromatin cohesion at centromere|maintenance of centromeric mitotic sister chromatin cohesion							mah	2011-06-01T04:10:59Z					biological_process											owl:Class	
GO:0140523	biolink:NamedThing	GTPase-dependent fusogenic activity	A GTPase activity that mediates the joining two lipid bilayers to form a single membrane.	tmpzr1t_l9r_go_relaxed.owl	membrane fusion GTPase activity	https://github.com/geneontology/go-ontology/issues/19942						pg	2020-09-24T09:49:40Z					molecular_function											owl:Class	
GO:0015864	biolink:NamedThing	pyrimidine nucleoside transport	The directed movement of a pyrimidine nucleoside, a pyrimidine base covalently bonded to a ribose or deoxyribose sugar, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1990033	biolink:NamedThing	dendritic branch point	The part of a dendritic tree where it branches, giving rise to a dendritic branch.	tmpzr1t_l9r_go_relaxed.owl	branch point of dendrite				NIF_Subcellular:sao1348591767			pr	2013-02-07T13:01:01Z					cellular_component											owl:Class	
GO:0044306	biolink:NamedThing	neuron projection terminus	The specialized, terminal region of a neuron projection such as an axon or a dendrite.	tmpzr1t_l9r_go_relaxed.owl	nerve terminal|neuron terminal specialization|neuron projection terminal							jl	2010-02-05T02:44:04Z					cellular_component											owl:Class	
GO:0090642	biolink:NamedThing	microsporidian-type exospore	The dense, protein rich outermost layer of a microsporidian spore wall that lies above the endospore.	tmpzr1t_l9r_go_relaxed.owl								tb	2015-05-04T14:17:06Z					cellular_component											owl:Class	
GO:0031160	biolink:NamedThing	spore wall	The specialized envelope lying outside the cell membrane of a spore.	tmpzr1t_l9r_go_relaxed.owl	spore coat													cellular_component											owl:Class	
GO:0021970	biolink:NamedThing	corticospinal neuron axon guidance through the basilar pons	The process in which the migration of an axon growth cone of a pyramidal cell that is part of the corticospinal tract is directed after exiting the cerebral peduncle through the basilar pons in response to a combination of attractive and repulsive cues.	tmpzr1t_l9r_go_relaxed.owl	corticospinal neuron axon pathfinding through the basilar pons													biological_process											owl:Class	
GO:0021525	biolink:NamedThing	lateral motor column neuron differentiation	The process in which differentiating motor neurons in the neural tube acquire the specialized structural and/or functional features of lateral motor column neurons. Lateral motor column neurons are generated only on limb levels and send axons into the limb mesenchyme. Differentiation includes the processes involved in commitment of a cell to a specific fate.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0001553	biolink:NamedThing	luteinization	The set of processes resulting in differentiation of theca and granulosa cells into luteal cells and in the formation of a corpus luteum after ovulation.	tmpzr1t_l9r_go_relaxed.owl	luteal phase				Wikipedia:Luteal_phase|Wikipedia:Luteinization									biological_process											owl:Class	
GO:0055102	biolink:NamedThing	lipase inhibitor activity	Binds to and stops, prevents or reduces the activity of a lipase, an enzyme that catalyzes of the hydrolysis of a lipid.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0045840	biolink:NamedThing	positive regulation of mitotic nuclear division	Any process that activates or increases the frequency, rate or extent of mitosis.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of mitosis|upregulation of mitosis|stimulation of mitosis|up-regulation of mitosis|mitogenic activity|activation of mitosis|up regulation of mitosis													biological_process											owl:Class	
GO:0022025	biolink:NamedThing	leukemia inhibitory factor signaling pathway involved in forebrain neuron fate commitment	Any series of molecular signals initiated by the binding of leukemia inhibitory factor to a receptor on the surface of the target cell, that contributes to the commitment of a neuroblast to a neuronal fate. The neuron will reside in the forebrain.	tmpzr1t_l9r_go_relaxed.owl	leukemia inhibitory factor signalling pathway involved in forebrain neuron fate commitment													biological_process											owl:Class	
GO:0039014	biolink:NamedThing	cell differentiation involved in pronephros development	The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the pronephros as it progresses from its formation to the mature state.	tmpzr1t_l9r_go_relaxed.owl	cell differentiation involved in pronephric kidney development							bf	2010-07-02T09:59:25Z					biological_process											owl:Class	
GO:0070266	biolink:NamedThing	necroptotic process	A programmed necrotic cell death process which begins when a cell receives a signal (e.g. a ligand binding to a death receptor or to a Toll-like receptor), and proceeds through a series of biochemical events (signaling pathways), characterized by activation of receptor-interacting serine/threonine-protein kinase 1 and/or 3 (RIPK1/3, also called RIP1/3) and by critical dependence on mixed lineage kinase domain-like (MLKL), and which typically lead to common morphological features of necrotic cell death. The process ends when the cell has died. The process is divided into a signaling phase, and an execution phase, which is triggered by the former.	tmpzr1t_l9r_go_relaxed.owl	induction of necroptosis by extracellular signals|extracellular signal-induced necroptosis|programmed necrotic cell death|establishment of necroptosis of activated-T cells|activation of necroptosis|parthanatos|RIPK1-mediated regulated necrosis|necroptosis|PARP-dependent cell death|activation of necroptosis of activated-T cells|TNF-induced necroptosis|establishment of necroptosis|induction of necroptosis of activated-T cells|programmed necrosis|activation of necroptosis in response to extracellular signals|induction of necroptosis|activation of necroptosis by extracellular signals					Examples of this are Birc2 and Birc3 (UniProt symbols Q62210 and O08863) in PMID:21052097.						GO:0060555|GO:0060554|GO:0060553		biological_process											owl:Class	
GO:1902568	biolink:NamedThing	positive regulation of eosinophil activation	Any process that activates or increases the frequency, rate or extent of eosinophil activation.	tmpzr1t_l9r_go_relaxed.owl	activation of eosinophil activation|up regulation of eosinophil activation|up-regulation of eosinophil activation|upregulation of eosinophil activation							ecu	2013-12-10T15:54:52Z					biological_process											owl:Class	
GO:0075313	biolink:NamedThing	basidium development	The process that leads to the development of basidium, a small, specialized club-shaped structure typically bearing four basidiospores at the tips of minute projections. The basidium is unique to Basidiomycetes and distinguishes them from other kinds of fungi.	tmpzr1t_l9r_go_relaxed.owl						Note that basidiospores and basidia are separate biological structures. The basidium is the structure that bear the basidiospores, but the development of the basidium is a different process than the formation of the basidiospores themselves. For this reason, GO:0034295 basidiospore formation and GO:0075313 basidium development are different terms and are not linked.								biological_process											owl:Class	
GO:0007362	biolink:NamedThing	terminal region determination	Specification of the terminal regions (the two non-segmented ends) of the embryo by the gap genes; exemplified in insects by the actions of huckebein and tailless gene products.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0007354	biolink:NamedThing	zygotic determination of anterior/posterior axis, embryo	The specification of the anterior/posterior axis of the embryo by products of genes expressed in the zygote; exemplified in insects by the gap genes, pair rule genes and segment polarity gene cascade.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1904409	biolink:NamedThing	regulation of secretory granule organization	Any process that modulates the frequency, rate or extent of secretory granule organization.	tmpzr1t_l9r_go_relaxed.owl	regulation of secretory granule organization and biogenesis|regulation of secretory granule organisation							sl	2015-06-25T19:40:42Z					biological_process											owl:Class	
GO:0033363	biolink:NamedThing	secretory granule organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a secretory granule. A secretory granule is a small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion.	tmpzr1t_l9r_go_relaxed.owl	secretory granule organization and biogenesis|secretory granule organisation													biological_process											owl:Class	
GO:0045979	biolink:NamedThing	positive regulation of nucleoside metabolic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving nucleosides.	tmpzr1t_l9r_go_relaxed.owl	stimulation of nucleoside metabolic process|upregulation of nucleoside metabolic process|up regulation of nucleoside metabolic process|up-regulation of nucleoside metabolic process|positive regulation of nucleoside metabolism|activation of nucleoside metabolic process													biological_process											owl:Class	
GO:0061436	biolink:NamedThing	establishment of skin barrier	Establishment of the epithelial barrier, the functional barrier in the skin that limits its permeability.	tmpzr1t_l9r_go_relaxed.owl	skin barrier development|establishment of epithelial barrier|epithelial barrier development							dph	2012-03-02T09:14:26Z					biological_process											owl:Class	
GO:0044185	biolink:NamedThing	host cell late endosome membrane	The lipid bilayer surrounding a host cell late endosome.	tmpzr1t_l9r_go_relaxed.owl								jl	2009-10-15T03:00:39Z					cellular_component											owl:Class	
GO:0044184	biolink:NamedThing	host cell late endosome	A prelysosomal endocytic organelle differentiated from host early endosomes by lower lumenal pH and different protein composition. Host late endosomes are more spherical than early endosomes and are mostly juxtanuclear, being concentrated near the microtubule organizing center.	tmpzr1t_l9r_go_relaxed.owl								jl	2009-10-15T02:58:34Z					cellular_component											owl:Class	
GO:0007298	biolink:NamedThing	border follicle cell migration	The directed movement of a border cell through the nurse cells to reach the oocyte. An example of this is found in Drosophila melanogaster.	tmpzr1t_l9r_go_relaxed.owl	border cell migration													biological_process											owl:Class	
GO:0001532	biolink:NamedThing	interleukin-21 receptor activity	Combining with interleukin-21 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	IL-21R|IL-21 receptor activity													molecular_function											owl:Class	
GO:0019977	biolink:NamedThing	interleukin-21 binding	Binding to interleukin-21.	tmpzr1t_l9r_go_relaxed.owl	IL-21 binding													molecular_function											owl:Class	
GO:0086081	biolink:NamedThing	cell adhesive protein binding involved in atrial cardiac muscle cell-AV node cell communication	Binding to a protein or protein complex that results in the connection of an atrial cardiomyocyte with an AV node cell and contributes to the communication between the two cells.	tmpzr1t_l9r_go_relaxed.owl	cell adhesive protein binding involved in atrial cardiomyocyte-atrioventricular node cell communication|cell adhesive protein binding involved in atrial cardiomyocyte-AV node cell communication							dph	2011-11-22T11:00:47Z					molecular_function											owl:Class	
GO:2001196	biolink:NamedThing	positive regulation of lysine biosynthetic process via alpha-aminoadipate and saccharopine	Any process that activates or increases the frequency, rate or extent of lysine biosynthetic process via alpha-aminoadipate and saccharopine.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of lysine biosynthesis via aminoadipic acid and saccharopine|positive regulation of lysine biosynthetic process via aminoadipic acid and saccharopine							mcc	2011-11-03T07:57:24Z					biological_process											owl:Class	
GO:0014063	biolink:NamedThing	negative regulation of serotonin secretion	Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of serotonin.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of serotonin release|inhibition of serotonin secretion|down regulation of serotonin secretion|down-regulation of serotonin secretion|downregulation of serotonin secretion													biological_process											owl:Class	
GO:1904863	biolink:NamedThing	regulation of beta-catenin-TCF complex assembly	Any process that modulates the frequency, rate or extent of beta-catenin-TCF complex assembly.	tmpzr1t_l9r_go_relaxed.owl	regulation of beta-catenin/LEF complex assembly|regulation of beta-catenin-TCF complex formation|regulation of beta-catenin/lymphoid enhancer binding factor complex assembly|regulation of beta-catenin/LEF complex formation|regulation of beta-catenin/lymphoid enhancer binding factor complex formation|regulation of beta-catenin/T-cell factor complex formation|regulation of beta-catenin/T-cell factor complex assembly							bf	2015-12-17T13:50:39Z					biological_process											owl:Class	
GO:1904837	biolink:NamedThing	beta-catenin-TCF complex assembly	The aggregation, arrangement and bonding together of a set of components to form a beta-catenin-TCF complex.	tmpzr1t_l9r_go_relaxed.owl	beta-catenin/T-cell factor complex formation|beta-catenin/lymphoid enhancer binding factor complex formation|beta-catenin/LEF complex assembly|beta-catenin/LEF complex formation|beta-catenin/T-cell factor complex assembly|beta-catenin-TCF complex formation|beta-catenin/lymphoid enhancer binding factor complex assembly							bf	2015-12-03T17:20:26Z					biological_process											owl:Class	
GO:0000735	biolink:NamedThing	removal of nonhomologous ends	The removal of nonhomologous sequences at the broken 3' single-strand DNA end before DNA repair synthesis can occur.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:2000456	biolink:NamedThing	negative regulation of T-helper 17 cell extravasation	Any process that stops, prevents or reduces the frequency, rate or extent of T-helper 17 cell extravasation.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-03-04T10:50:29Z					biological_process											owl:Class	
GO:0042494	biolink:NamedThing	detection of bacterial lipoprotein	The series of events in which a bacterial lipoprotein stimulus is received by a cell and converted into a molecular signal. Bacterial lipoproteins are lipoproteins characterized by the presence of conserved sequence motifs called pathogen-associated molecular patterns (PAMPs).	tmpzr1t_l9r_go_relaxed.owl	perception of bacterial lipoprotein|detection of Lpp|perception of BLP|perception of Lpp|detection of BLP													biological_process											owl:Class	
GO:0016045	biolink:NamedThing	detection of bacterium	The series of events in which a stimulus from a bacterium is received and converted into a molecular signal.	tmpzr1t_l9r_go_relaxed.owl	perception of bacterium|perception of bacteria|detection of bacteria											GO:0009681|GO:0009598		biological_process											owl:Class	
GO:0120077	biolink:NamedThing	angiogenic sprout fusion	The connection of an angiogenic sprout to another vessel or sprout during the formation of vascular networks by sprouting angiogenesis.	tmpzr1t_l9r_go_relaxed.owl	blood vessel anastomosis	https://github.com/geneontology/go-ontology/issues/13690						krc	2017-06-27T21:16:55Z					biological_process											owl:Class	
GO:0007156	biolink:NamedThing	homophilic cell adhesion via plasma membrane adhesion molecules	The attachment of a plasma membrane adhesion molecule in one cell to an identical molecule in an adjacent cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0072231	biolink:NamedThing	metanephric proximal convoluted tubule segment 1 development	The process whose specific outcome is the progression of the S1 portion of the metanephric proximal convoluted tubule over time, from its formation to the mature structure. The S1 portion is the initial portion of the metanephric proximal convoluted tubule and is responsible for avid reabsorption of water and solutes.	tmpzr1t_l9r_go_relaxed.owl	metanephric S1 development							mah	2010-03-18T03:39:10Z					biological_process											owl:Class	
GO:0072229	biolink:NamedThing	metanephric proximal convoluted tubule development	The process whose specific outcome is the progression of the metanephric proximal convoluted tubule over time, from its formation to the mature structure. The metanephric proximal convoluted tubule is the most proximal portion of the metanephric proximal tubule and extends from the metanephric glomerular capsule to the metanephric proximal straight tubule.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-03-18T03:37:56Z					biological_process											owl:Class	
GO:0007205	biolink:NamedThing	protein kinase C-activating G protein-coupled receptor signaling pathway	The series of molecular signals generated as a consequence of a G protein-coupled receptor binding to its physiological ligand, where the pathway proceeds with activation of protein kinase C (PKC). PKC is activated by second messengers including diacylglycerol (DAG).	tmpzr1t_l9r_go_relaxed.owl	activation of protein kinase C activity by G-protein coupled receptor protein signalling pathway|protein kinase C-activating G-protein coupled receptor signaling pathway|activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway													biological_process											owl:Class	
GO:0034515	biolink:NamedThing	proteasome storage granule	An aggregation of proteasome core protease (CP) and regulatory particle (RP) complexes that localizes in the cytoplasm as dot-like structures when cells are in a quiescent state.	tmpzr1t_l9r_go_relaxed.owl	PSG	https://github.com/geneontology/go-ontology/issues/20297												cellular_component											owl:Class	
GO:0007359	biolink:NamedThing	posterior abdomen determination	The regionalization process in which the posterior (abdominal) regions of the embryo are specified by the gap genes.	tmpzr1t_l9r_go_relaxed.owl						Note that this process is exemplified in insects by the actions of the knirps gene product.								biological_process											owl:Class	
GO:1900038	biolink:NamedThing	negative regulation of cellular response to hypoxia	Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to hypoxia.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of cellular response to hypoxia|negative regulation of cellular response to lowered oxygen tension|negative regulation of cellular response to hypoxic stress|down-regulation of cellular response to hypoxic stress|downregulation of cellular response to hypoxic stress|downregulation of cellular response to lowered oxygen tension|inhibition of cellular response to hypoxia|down regulation of cellular response to lowered oxygen tension|downregulation of cellular response to hypoxia|down-regulation of cellular response to lowered oxygen tension|down regulation of cellular response to hypoxic stress|down regulation of cellular response to hypoxia|inhibition of cellular response to hypoxic stress|inhibition of cellular response to lowered oxygen tension							yaf	2012-01-17T09:29:16Z					biological_process											owl:Class	
GO:0042714	biolink:NamedThing	dosage compensation complex assembly	The aggregation, arrangement and bonding together of proteins on DNA or RNA to form the complex that mediates dosage compensation on one or more X chromosomes.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0034098	biolink:NamedThing	VCP-NPL4-UFD1 AAA ATPase complex	A multiprotein ATPase complex required for the efficient dislocation of ER-lumenal degradation substrates, and their subsequent proteolysis by the proteasome. In budding yeast, this complex includes Cdc48p, Npl4p and Ufd1p proteins. In mammals, this complex includes a hexamer of VCP/p97 (a cytosolic ATPase) and trimers of each of its cofactors UFD1L and NPL4 (NPLOC4) (e.g. a 6:3:3 stoichiometry).	tmpzr1t_l9r_go_relaxed.owl	p97-Ufd1-Npl4 complex|Cdc48p-Npl4p-Ufd1p AAA ATPase complex													cellular_component											owl:Class	
GO:0033206	biolink:NamedThing	meiotic cytokinesis	A cell cycle process that results in the division of the cytoplasm of a cell after meiosis, resulting in the separation of the original cell into two daughter cells.	tmpzr1t_l9r_go_relaxed.owl	cytokinesis after meiosis													biological_process											owl:Class	
GO:0060682	biolink:NamedThing	primary ureteric bud growth	The process in which the primary ureteric bud grows along its axis dorsally toward the metanephric blastema.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-06-02T02:56:01Z					biological_process											owl:Class	
GO:0000964	biolink:NamedThing	mitochondrial RNA 5'-end processing	Any process involved in forming the mature 5' end of an RNA molecule transcribed from a mitochondrial genome; occurs in the mitochondrion.	tmpzr1t_l9r_go_relaxed.owl	mitochondrial RNA 5' end processing													biological_process											owl:Class	
GO:0030244	biolink:NamedThing	cellulose biosynthetic process	The chemical reactions and pathways resulting in the formation of cellulose, a linear beta1-4 glucan of molecular mass 50-400 kDa with the pyranose units in the -4C1 conformation.	tmpzr1t_l9r_go_relaxed.owl	cellulose biosynthesis|cellulose anabolism|cellulose synthesis|cellulose formation				MetaCyc:PWY-1001							GO:0016178		biological_process											owl:Class	
GO:0032916	biolink:NamedThing	positive regulation of transforming growth factor beta3 production	Any process that activates or increases the frequency, rate, or extent of production of transforming growth factor-beta3.	tmpzr1t_l9r_go_relaxed.owl	stimulation of transforming growth factor-beta3 production|up-regulation of transforming growth factor-beta3 production|upregulation of transforming growth factor-beta3 production|positive regulation of TGF-B3 production|positive regulation of TGFB3 production|up regulation of transforming growth factor-beta3 production|positive regulation of transforming growth factor-beta3 production|activation of transforming growth factor-beta3 production													biological_process											owl:Class	
GO:0048750	biolink:NamedThing	compound eye corneal lens morphogenesis	The process in which the anatomical structures of the compound eye corneal lens are generated and organized.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0007250	biolink:NamedThing	activation of NF-kappaB-inducing kinase activity	The stimulation of the activity of NF-kappaB-inducing kinase through phosphorylation at specific residues.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of NF-kappaB-inducing kinase activity|activation of NIK activity													biological_process											owl:Class	
GO:0140584	biolink:NamedThing	chromatin extrusion motor activity	A DNA translocase activity that folds chromosomal DNA and catalytically extends the newly formed loop, driven by ATP hydrolysis.	tmpzr1t_l9r_go_relaxed.owl	chromatin extrusion activity	https://github.com/geneontology/go-ontology/issues/21647|https://github.com/geneontology/go-ontology/issues/20204						pg	2021-02-01T13:42:08Z					molecular_function											owl:Class	
GO:0010071	biolink:NamedThing	root meristem specification	The specification of a meristem which will give rise to a primary or lateral root.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0021510	biolink:NamedThing	spinal cord development	The process whose specific outcome is the progression of the spinal cord over time, from its formation to the mature structure. The spinal cord primarily conducts sensory and motor nerve impulses between the brain and the peripheral nervous tissues.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0047805	biolink:NamedThing	cytidylate cyclase activity	Catalysis of the reaction: CTP = 3',5'-cyclic CMP + diphosphate + H(+).	tmpzr1t_l9r_go_relaxed.owl	CTP diphosphate-lyase (cyclizing; 3',5'-cyclic-CMP-forming)|cytidyl cyclase activity|3'5'-cyclic-CMP synthase activity|cytidylyl cyclase activity|CTP diphosphate-lyase (cyclizing)|3',5'-cyclic-CMP synthase activity				EC:4.6.1.6|RHEA:14737|MetaCyc:CYTIDYLATE-CYCLASE-RXN|KEGG_REACTION:R00574									molecular_function											owl:Class	
GO:0048136	biolink:NamedThing	male germ-line cyst formation	Formation of a group of interconnected cells derived from a single male gonial founder cell.	tmpzr1t_l9r_go_relaxed.owl	male germline cyst formation													biological_process											owl:Class	
GO:0048134	biolink:NamedThing	germ-line cyst formation	Formation of a group of interconnected cells derived from a single gonial founder cell.	tmpzr1t_l9r_go_relaxed.owl	germline cyst formation													biological_process											owl:Class	
GO:0044872	biolink:NamedThing	lipoprotein localization	Any process in which a lipoprotein is transported to, or maintained in, a specific location.	tmpzr1t_l9r_go_relaxed.owl								jl	2014-11-25T16:27:06Z					biological_process											owl:Class	
GO:0005703	biolink:NamedThing	polytene chromosome puff	A swelling at a site along the length of a polytene chromosome, thought to be the site of active transcription.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0047766	biolink:NamedThing	carbamoyl-serine ammonia-lyase activity	Catalysis of the reaction: O-carbamoyl-L-serine + H(2)O + H(+) = CO(2) + 2 NH(4)(+) + pyruvate.	tmpzr1t_l9r_go_relaxed.owl	O-carbamoyl-L-serine ammonia-lyase (pyruvate-forming)|carbamoylserine deaminase activity|O-carbamoyl-L-serine ammonia-lyase (decarboxylating; pyruvate-forming)|O-carbamoyl-L-serine deaminase activity				RHEA:15445|MetaCyc:CARBAMOYL-SERINE-AMMONIA-LYASE-RXN|KEGG_REACTION:R00213|EC:4.3.1.13									molecular_function											owl:Class	
GO:0099056	biolink:NamedThing	integral component of presynaptic membrane	The component of the presynaptic membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.	tmpzr1t_l9r_go_relaxed.owl	integral component of presynaptic plasma membrane													cellular_component											owl:Class	
GO:0061585	biolink:NamedThing	hypocretin secretion, neurotransmission	The controlled release of a peptide from a cell or a tissue in which the peptide acts as a neurotransmitter.	tmpzr1t_l9r_go_relaxed.owl	orexin secretion, neurotransmission							dph	2013-12-26T10:09:37Z					biological_process											owl:Class	
GO:1901754	biolink:NamedThing	vitamin D3 catabolic process	The chemical reactions and pathways resulting in the breakdown of vitamin D3.	tmpzr1t_l9r_go_relaxed.owl	vitamin D3 breakdown|calciol breakdown|cholecalciferol catabolic process|vitamin D3 catabolism|vitamin D3 degradation|calciol catabolism|calciol degradation|cholecalciferol catabolism|calciol catabolic process							yaf	2013-01-14T11:11:04Z					biological_process											owl:Class	
GO:0033726	biolink:NamedThing	aldehyde ferredoxin oxidoreductase activity	Catalysis of the reaction: an aldehyde + H2O + 2 oxidized ferredoxin = an acid + 2 H+ + 2 reduced ferredoxin.	tmpzr1t_l9r_go_relaxed.owl	AOR|tungsten-containing aldehyde ferredoxin oxidoreductase activity|aldehyde:ferredoxin oxidoreductase activity				EC:1.2.7.5|RHEA:16421|MetaCyc:1.2.7.5-RXN									molecular_function											owl:Class	
GO:0042158	biolink:NamedThing	lipoprotein biosynthetic process	The chemical reactions and pathways resulting in the formation of any conjugated, water-soluble protein in which the covalently attached nonprotein group consists of a lipid or lipids.	tmpzr1t_l9r_go_relaxed.owl	lipoprotein anabolism|lipoprotein synthesis|lipoprotein formation|lipoprotein biosynthesis													biological_process											owl:Class	
GO:0015304	biolink:NamedThing	glucose uniporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucose(out) = glucose(in).	tmpzr1t_l9r_go_relaxed.owl	galactose, glucose uniporter activity													molecular_function											owl:Class	
GO:0018632	biolink:NamedThing	4-nitrophenol 4-monooxygenase activity	Catalysis of the reaction: p-nitrophenol + O2 + NADPH = H2O + NADP+ + nitrite + p-benzoquinone.	tmpzr1t_l9r_go_relaxed.owl					EC:1.14.13.167|RHEA:34327|UM-BBD_reactionID:r0226|MetaCyc:RXN-8739									molecular_function											owl:Class	
GO:0102286	biolink:NamedThing	ornithine N-delta-acetyltransferase activity	Catalysis of the reaction: L-ornithinium(1+) = N(5)-acetyl-L-ornithine.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-12667									molecular_function											owl:Class	
GO:1904736	biolink:NamedThing	negative regulation of fatty acid beta-oxidation using acyl-CoA dehydrogenase	Any process that stops, prevents or reduces the frequency, rate or extent of fatty acid beta-oxidation using acyl-CoA dehydrogenase.	tmpzr1t_l9r_go_relaxed.owl	inhibition of fatty acid beta-oxidation using acyl-CoA dehydrogenase|down regulation of fatty acid beta-oxidation using acyl-CoA dehydrogenase|down-regulation of fatty acid beta-oxidation using acyl-CoA dehydrogenase|downregulation of fatty acid beta-oxidation using acyl-CoA dehydrogenase							lb	2015-10-15T08:14:57Z					biological_process											owl:Class	
GO:0032945	biolink:NamedThing	negative regulation of mononuclear cell proliferation	Any process that stops, prevents, or reduces the frequency, rate or extent of mononuclear cell proliferation.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of PBMC proliferation|negative regulation of peripheral blood mononuclear cell proliferation													biological_process											owl:Class	
GO:0033080	biolink:NamedThing	immature T cell proliferation in thymus	The expansion of an immature T cell population by cell division in the thymus.	tmpzr1t_l9r_go_relaxed.owl	thymic T cell proliferation|thymocyte proliferation|thymocyte cell proliferation													biological_process											owl:Class	
GO:0051663	biolink:NamedThing	oocyte nucleus localization involved in oocyte dorsal/ventral axis specification	The directed movement of the nucleus to a specific location within a cell during the establishment and maintenance of the dorsal/ventral axis of the oocyte.	tmpzr1t_l9r_go_relaxed.owl	oocyte nucleus localisation involved in oocyte dorsal/ventral axis specification|oocyte nucleus localization involved in oocyte dorsal-ventral axis specification|oocyte nucleus localization during oocyte axis determination|oocyte nucleus localization involved in oocyte dorsal/ventral axis determination|oocyte nucleus localization involved in oocyte dorsoventral axis specification|oocyte axis determination, oocyte nucleus localization|establishment and maintenance of oocyte nucleus localization during oocyte axis determination											GO:0051662		biological_process											owl:Class	
GO:0015083	biolink:NamedThing	aluminum ion transmembrane transporter activity	Enables the transfer of aluminum (Al) ions from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	aluminium ion transporter activity|aluminum resistance permease activity|aluminium resistance permease activity											GO:0015084		molecular_function											owl:Class	
GO:0021986	biolink:NamedThing	habenula development	The progression of the habenula over time from its initial formation until its mature state. The habenula is the group of nuclei that makes up the stalk of the pineal gland.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0046216	biolink:NamedThing	indole phytoalexin catabolic process	The chemical reactions and pathways resulting in the breakdown of indole phytoalexins, any indole compound produced by plants as part of their defense response.	tmpzr1t_l9r_go_relaxed.owl	indole phytoalexin breakdown|indole phytoalexin catabolism|indole phytoalexin degradation													biological_process											owl:Class	
GO:0010030	biolink:NamedThing	positive regulation of seed germination	Any process that activates or increase the rate of seed germination.	tmpzr1t_l9r_go_relaxed.owl	up regulation of seed germination|activation of seed germination|stimulation of seed germination|up-regulation of seed germination|upregulation of seed germination													biological_process											owl:Class	
GO:0071373	biolink:NamedThing	cellular response to luteinizing hormone stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a luteinizing hormone stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-12-11T03:16:02Z					biological_process											owl:Class	
GO:1904363	biolink:NamedThing	negative regulation of calcitonin secretion	Any process that stops, prevents or reduces the frequency, rate or extent of calcitonin secretion.	tmpzr1t_l9r_go_relaxed.owl	down regulation of calcitonin secretion|down-regulation of calcitonin secretion|downregulation of calcitonin secretion|inhibition of calcitonin secretion							sl	2015-06-15T17:54:58Z					biological_process											owl:Class	
GO:1904644	biolink:NamedThing	cellular response to curcumin	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a curcumin stimulus.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-08-31T20:38:17Z					biological_process											owl:Class	
GO:0034020	biolink:NamedThing	neoxanthin synthase activity	Catalysis of the reaction: all-trans-violaxanthin = all-trans-neoxanthin.	tmpzr1t_l9r_go_relaxed.owl	NSY|violaxanthin-neoxanthin isomerase (epoxide-opening) activity				EC:5.3.99.9|RHEA:10128|KEGG_REACTION:R06948|MetaCyc:RXN1F-155									molecular_function											owl:Class	
GO:0019240	biolink:NamedThing	citrulline biosynthetic process	The chemical reactions and pathways resulting in the formation of citrulline, N5-carbamoyl-L-ornithine, an alpha amino acid not found in proteins.	tmpzr1t_l9r_go_relaxed.owl	citrulline formation|citrulline synthesis|citrulline anabolism|citrulline biosynthesis				MetaCyc:CITRULBIO-PWY									biological_process											owl:Class	
GO:0000052	biolink:NamedThing	citrulline metabolic process	The chemical reactions and pathways involving citrulline, N5-carbamoyl-L-ornithine, an alpha amino acid not found in proteins.	tmpzr1t_l9r_go_relaxed.owl	citrulline metabolism													biological_process											owl:Class	
GO:0106328	biolink:NamedThing	acetylgalactosaminyl-O-glycosyl-seryl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity	Catalysis of the reaction: 3-O-[N-acetyl-alpha-D-galactosaminyl]-L-seryl-[protein] + UDP-N-acetyl-alpha-D-glucosamine = 3-O-[N-acetyl-beta-D-glucosaminyl-(1->3)-N-acetyl-alpha-D-galactosaminyl]-L-seryl-[protein] + H(+) + UDP.	tmpzr1t_l9r_go_relaxed.owl					RHEA:46884|EC:2.4.1.147			hjd	2020-09-30T13:46:37Z					molecular_function											owl:Class	
GO:0036213	biolink:NamedThing	contractile ring contraction	The process of an actomyosin ring getting smaller in diameter.	tmpzr1t_l9r_go_relaxed.owl	contractile ring constriction	https://github.com/geneontology/go-ontology/issues/21855				This term can be used to annotate contraction of either bacterial or fungal contractile rings.		bf	2012-04-26T02:58:18Z					biological_process											owl:Class	
GO:0033504	biolink:NamedThing	floor plate development	The progression of the floor plate over time from its initial formation until its mature state.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0046585	biolink:NamedThing	enniatin biosynthetic process	The chemical reactions and pathways resulting in the formation of enniatins, any of various cyclodepsipeptide antibiotics from Fusarium species that function as ionophores.	tmpzr1t_l9r_go_relaxed.owl	enniatin formation|enniatin synthesis|enniatin biosynthesis|enniatin anabolism													biological_process											owl:Class	
GO:0035697	biolink:NamedThing	CD8-positive, alpha-beta T cell extravasation	The migration of a CD8-positive, alpha-beta T cell from the blood vessels into the surrounding tissue.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-02-28T03:08:49Z					biological_process											owl:Class	
GO:0033975	biolink:NamedThing	(R)-2-haloacid dehalogenase activity	Catalysis of the reaction: (R)-2-haloacid + H2O = (S)-2-hydroxyacid + halide.	tmpzr1t_l9r_go_relaxed.owl	D-DEX|(R)-2-haloacid halidohydrolase activity|2-haloalkanoid acid halidohydrolase activity|D-2-haloacid dehalogenase activity|2-haloalkanoic acid dehalogenase activity				EC:3.8.1.9|MetaCyc:3.8.1.9-RXN									molecular_function											owl:Class	
GO:0071709	biolink:NamedThing	membrane assembly	The aggregation, arrangement and bonding together of a set of components to form a membrane.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-03-10T11:19:17Z					biological_process											owl:Class	
GO:0042691	biolink:NamedThing	positive regulation of crystal cell differentiation	Any process that activates or increases the frequency, rate or extent of crystal cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	stimulation of crystal cell differentiation|up-regulation of crystal cell differentiation|upregulation of crystal cell differentiation|activation of crystal cell differentiation|up regulation of crystal cell differentiation													biological_process											owl:Class	
GO:0035702	biolink:NamedThing	monocyte homeostasis	The process of regulating the proliferation and elimination of monocytes such that the total number of monocytes within a whole or part of an organism is stable over time in the absence of an outside stimulus.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-03-02T11:32:57Z					biological_process											owl:Class	
GO:0090650	biolink:NamedThing	cellular response to oxygen-glucose deprivation	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the deprivation of oxygen and glucose.	tmpzr1t_l9r_go_relaxed.owl	cellular response to OGD							tb	2015-07-01T10:27:29Z					biological_process											owl:Class	
GO:0036294	biolink:NamedThing	cellular response to decreased oxygen levels	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting a decline in the level of oxygen.	tmpzr1t_l9r_go_relaxed.owl	cellular response to lowered oxygen levels					This term should be used when a decrease in oxygen levels is not considered a stress response. For a hypoxic stress response, consider instead 'cellular response to hypoxia ; GO:0071456'.		bf	2012-07-20T01:08:40Z					biological_process											owl:Class	
GO:0043755	biolink:NamedThing	alpha-ribazole phosphatase activity	Catalysis of the reaction: alpha-ribazole 5'-phosphate + H(2)O = alpha-ribazole + phosphate.	tmpzr1t_l9r_go_relaxed.owl	CobC|alpha-ribazole-5'-P phosphatase activity|alpha-ribazole-5'-phosphate phosphohydrolase activity				MetaCyc:RIBAZOLEPHOSPHAT-RXN|RHEA:24456|EC:3.1.3.73|KEGG_REACTION:R04594							GO:0019175		molecular_function											owl:Class	
GO:0014030	biolink:NamedThing	mesenchymal cell fate commitment	The process in which a cell becomes committed to become a mesenchymal cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0098560	biolink:NamedThing	cytoplasmic side of late endosome membrane	The side (leaflet) of the late endosome membrane that faces the cytoplasm.	tmpzr1t_l9r_go_relaxed.owl	external side of late endosome membrane|external leaflet of late endosome membrane					In GO, 'external side' still refers to part of the membrane and does not refer to components beyond (outside of) the membrane.								cellular_component											owl:Class	
GO:0010009	biolink:NamedThing	cytoplasmic side of endosome membrane	The side (leaflet) of the endosome membrane that faces the cytoplasm.	tmpzr1t_l9r_go_relaxed.owl	external leaflet of endosome membrane|external side of endosome membrane													cellular_component											owl:Class	
GO:0045879	biolink:NamedThing	negative regulation of smoothened signaling pathway	Any process that stops, prevents, or reduces the frequency, rate or extent of smoothened signaling.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of smoothened by patched|inhibition of smoothened signaling pathway|negative regulation of smoothened signalling pathway|downregulation of smoothened signaling pathway|negative regulation of smoothened activity|negative regulation of smoothened receptor activity by patched|down-regulation of smoothened signaling pathway|down regulation of smoothened signaling pathway|negative regulation of hedgehog signaling pathway|negative regulation of hh signaling pathway											GO:0045877		biological_process											owl:Class	
GO:0008589	biolink:NamedThing	regulation of smoothened signaling pathway	Any process that modulates the frequency, rate or extent of smoothened signaling.	tmpzr1t_l9r_go_relaxed.owl	regulation of hedgehog signaling pathway|regulation of hh signaling pathway|regulation of smoothened signalling pathway|regulation of smoothened by patched|regulation of smoothened receptor activity by patched|regulation of smoothened activity											GO:0043109|GO:0007226		biological_process											owl:Class	
GO:0033877	biolink:NamedThing	succinyl-CoA:(R)-benzylsuccinate CoA-transferase activity	Catalysis of the reaction: (R)-2-benzylsuccinate + succinyl-CoA = (R)-2-benzylsuccinyl-CoA + succinate.	tmpzr1t_l9r_go_relaxed.owl	succinyl-CoA:benzylsuccinate CoA-transferase activity|benzylsuccinate CoA-transferase activity|succinyl-CoA:(R)-2-benzylsuccinate CoA-transferase activity				KEGG_REACTION:R05588|MetaCyc:RXN-864|UM-BBD_reactionID:r0329|EC:2.8.3.15|RHEA:16469							GO:0018728		molecular_function											owl:Class	
GO:0018726	biolink:NamedThing	9-phenanthrol sulfotransferase activity	Catalysis of the reaction: 9-phenanthrol + X-SO3(-) = HX + 9-phenanthrylsulfate.	tmpzr1t_l9r_go_relaxed.owl	9-phenanthrol sulphotransferase activity				UM-BBD_reactionID:r0564									molecular_function											owl:Class	
GO:0031996	biolink:NamedThing	thioesterase binding	Binding to a thioesterase.	tmpzr1t_l9r_go_relaxed.owl	thiolesterase binding													molecular_function											owl:Class	
GO:2000066	biolink:NamedThing	positive regulation of cortisol biosynthetic process	Any process that activates or increases the frequency, rate or extent of cortisol biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of cortisol biosynthesis|positive regulation of cortisol anabolism|positive regulation of cortisol synthesis|positive regulation of cortisol formation							jl	2010-08-20T01:51:32Z					biological_process											owl:Class	
GO:2000064	biolink:NamedThing	regulation of cortisol biosynthetic process	Any process that modulates the frequency, rate or extent of cortisol biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of cortisol synthesis|regulation of cortisol anabolism|regulation of cortisol biosynthesis|regulation of cortisol formation							jl	2010-08-20T01:51:15Z					biological_process											owl:Class	
GO:0033585	biolink:NamedThing	L-phenylalanine biosynthetic process from chorismate via phenylpyruvate	The chemical reactions and pathways resulting in the formation of L-phenylalanine from other compounds, including chorismate, via the intermediate phenylpyruvate.	tmpzr1t_l9r_go_relaxed.owl	L-phenylalanine formation from chorismate via phenylpyruvate|L-phenylalanine synthesis from chorismate via phenylpyruvate|L-phenylalanine biosynthesis from chorismate via phenylpyruvate|L-phenylalanine anabolism from chorismate via phenylpyruvate				MetaCyc:PHESYN									biological_process											owl:Class	
GO:0002537	biolink:NamedThing	nitric oxide production involved in inflammatory response	The synthesis or release of nitric oxide following a stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels.	tmpzr1t_l9r_go_relaxed.owl	production of nitric oxide involved in acute inflammatory response|nitric oxide production involved in acute inflammatory response|production of nitric oxide involved in inflammatory response													biological_process											owl:Class	
GO:0002532	biolink:NamedThing	production of molecular mediator involved in inflammatory response	The synthesis or release of any molecular mediator of the inflammatory response following an inflammatory stimulus, resulting in an increase in its intracellular or extracellular levels.	tmpzr1t_l9r_go_relaxed.owl	production of molecular mediator involved in acute inflammatory response|production of cellular mediator of acute inflammation													biological_process											owl:Class	
GO:0033511	biolink:NamedThing	luteolin biosynthetic process	The chemical reactions and pathways resulting in the formation of luteolin, 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4-one.	tmpzr1t_l9r_go_relaxed.owl	luteolin synthesis|luteolin biosynthesis|luteolin formation|luteolin anabolism				MetaCyc:PWY-5060									biological_process											owl:Class	
GO:1901780	biolink:NamedThing	pentalenolactone biosynthetic process	The chemical reactions and pathways resulting in the formation of pentalenolactone.	tmpzr1t_l9r_go_relaxed.owl	pentalenolactone biosynthesis|pentalenolactone formation|pentalenolactone anabolism|pentalenolactone synthesis							yaf	2013-01-16T09:49:47Z					biological_process											owl:Class	
GO:0030976	biolink:NamedThing	thiamine pyrophosphate binding	Binding to thiamine pyrophosphate, the diphosphoric ester of thiamine. Acts as a coenzyme of several (de)carboxylases, transketolases, and alpha-oxoacid dehydrogenases.	tmpzr1t_l9r_go_relaxed.owl	TPP binding|diphosphothiamin binding|thiamin pyrophosphate binding|cocarboxylase binding|aneurine pyrophosphate binding													molecular_function											owl:Class	
GO:0001015	biolink:NamedThing	snoRNA transcription by RNA polymerase II	The synthesis of small nucleolar RNA (snoRNA) from a DNA template by RNA polymerase II, originating at an RNA polymerase II promoter.	tmpzr1t_l9r_go_relaxed.owl	snoRNA transcription from an RNA polymerase II promoter	https://github.com/geneontology/go-ontology/issues/14854						krc	2010-08-18T07:21:18Z					biological_process											owl:Class	
GO:0022850	biolink:NamedThing	serotonin-gated cation-selective channel activity	Enables the transmembrane transfer of a cation by a channel that opens when serotonin has been bound by the channel complex or one of its constituent parts.	tmpzr1t_l9r_go_relaxed.owl	5-hydroxytryptamine-gated receptor-channel|serotonin-activated cation-selective channel activity|serotonin-gated cation channel activity				Reactome:R-HSA-9648983|Reactome:R-HSA-975311	Note that this term represents an activity and not a gene product. Consider also annotating to the molecular function term 'G protein-coupled serotonin receptor activity ; GO:0004993'.						GO:0005232		molecular_function											owl:Class	
GO:0033272	biolink:NamedThing	myo-inositol hexakisphosphate transport	The directed movement of myo-inositol hexakisphosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	phytate transport													biological_process											owl:Class	
GO:0033271	biolink:NamedThing	myo-inositol phosphate transport	The directed movement of any phosphorylated myo-inositol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0015952	biolink:NamedThing	purine deoxyribonucleotide interconversion	The chemical reactions and pathways by which a purine deoxyribonucleotide is synthesized from another purine deoxyribonucleotide.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0031026	biolink:NamedThing	glutamate synthase complex	A complex that possesses glutamate synthase activity.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0043961	biolink:NamedThing	succinyl-CoA:(R)-citramalate CoA-transferase activity	Catalysis of the reaction: succinyl-CoA + (R)-citramalate = succinate + (R)-citramalyl-CoA.	tmpzr1t_l9r_go_relaxed.owl	L-carnitine dehydratase/bile acid-inducible protein F|succinyl-CoA:R-citramalate CoA transferase|succinyl-CoA:(R)-citramalate CoA transferase activity				MetaCyc:RXN-8966|RHEA:38279|EC:2.8.3.20									molecular_function											owl:Class	
GO:0044158	biolink:NamedThing	host cell wall	The rigid or semi-rigid envelope lying outside the host cell membrane of plant, fungal, and most prokaryotic cells, maintaining their shape and protecting them from osmotic lysis. In plants it is made of cellulose and, often, lignin; in fungi it is composed largely of polysaccharides; in bacteria it is composed of peptidoglycan.	tmpzr1t_l9r_go_relaxed.owl								jl	2009-08-11T04:09:23Z					cellular_component											owl:Class	
GO:0102774	biolink:NamedThing	p-coumaroyltriacetic acid lactone synthase activity	Catalysis of the reaction: 2 H+ + 4-coumaryl-CoA + 3 malonyl-CoA( <=> p-coumaroyltriacetic acid lactone + 4 coenzyme A + 3 carbon dioxide.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-7822									molecular_function											owl:Class	
GO:1990397	biolink:NamedThing	queuosine salvage	Any process which produces queuosine from derivatives of it, without de novo synthesis.	tmpzr1t_l9r_go_relaxed.owl								pr	2014-06-10T14:56:12Z					biological_process											owl:Class	
GO:1905146	biolink:NamedThing	lysosomal protein catabolic process	Any cellular protein catabolic process that takes place in a lysosome.	tmpzr1t_l9r_go_relaxed.owl	proteolysis within lysosome|cellular protein degradation in lysosome|cellular protein catabolic process in lysosome|lysosomal protein degradation|lysosomal protein catabolism|cellular protein breakdown in lysosome|cellular protein catabolism in lysosome|lysosomal proteolysis					Also consider annotating to the term 'autophagy ; GO:0006914' or one of its descendants.		bf	2016-04-14T12:50:34Z					biological_process											owl:Class	
GO:0035141	biolink:NamedThing	medial fin morphogenesis	The process in which the anatomical structures of the medial fin are generated and organized. A medial fin is an unpaired fin of fish, usually located dorsomedially or ventromedially and primarily used for stability while swimming.	tmpzr1t_l9r_go_relaxed.owl	median fin morphogenesis|unpaired fin morphogenesis													biological_process											owl:Class	
GO:0045819	biolink:NamedThing	positive regulation of glycogen catabolic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glycogen.	tmpzr1t_l9r_go_relaxed.owl	up regulation of glycogen catabolic process|positive regulation of glycogen catabolism|positive regulation of glycogen breakdown|positive regulation of glycogenolysis|upregulation of glycogen catabolic process|up-regulation of glycogen catabolic process|positive regulation of glycogen degradation|activation of glycogen catabolic process|stimulation of glycogen catabolic process													biological_process											owl:Class	
GO:0008852	biolink:NamedThing	exodeoxyribonuclease I activity	Catalysis of the degradation of single-stranded DNA. It acts progressively in a 3' to 5' direction, releasing 5'-phosphomononucleotides.	tmpzr1t_l9r_go_relaxed.owl	E. coli exonuclease I activity|Escherichia coli exonuclease I|exonuclease I activity|E. coli exonuclease I				EC:3.1.11.1|MetaCyc:3.1.11.1-RXN									molecular_function											owl:Class	
GO:0018047	biolink:NamedThing	C-terminal peptidyl-phenylalanine amidation	The formation of a C-terminal peptidyl-phenylalanine amide by hydrolysis and oxidation of an interior Phe-Gly peptide in a secreted protein.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0094									biological_process											owl:Class	
GO:0010574	biolink:NamedThing	regulation of vascular endothelial growth factor production	Any process that modulates the frequency, rate, or extent of production of vascular endothelial growth factor.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0038013	biolink:NamedThing	positive regulation of Wnt signaling pathway by Wnt receptor internalization	Any process in which internalization of a Wnt receptor activates or increases the frequency, rate or extent of the Wnt signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of Wnt-activated signaling pathway by Wnt receptor internalization|positive regulation of Wnt receptor signaling pathway by Wnt receptor internalization|positive regulation of Wnt receptor signalling pathway by Wnt receptor endocytosis|positive regulation of Wnt receptor signaling pathway by LRP6 internalization|positive regulation of Wnt receptor signaling pathway by Frizzled internalization							bf	2011-06-23T04:02:21Z					biological_process											owl:Class	
GO:0038010	biolink:NamedThing	positive regulation of signal transduction by receptor internalization	Any process in which the internalization of a signaling receptor activates or increases the frequency, rate or extent of signal transduction. Receptor internalization can enhance signaling by concentrating signaling molecules in one location, or by moving a ligand-activated receptor to the location of downstream signaling proteins. Endosomes for example can serve as important intracellular signaling platforms.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of signaling pathway by receptor endocytosis							bf	2011-06-23T03:37:10Z					biological_process											owl:Class	
GO:2000413	biolink:NamedThing	regulation of fibronectin-dependent thymocyte migration	Any process that modulates the frequency, rate or extent of fibronectin-dependent thymocyte migration.	tmpzr1t_l9r_go_relaxed.owl	regulation of fibronectin-dependent immature T cell migration|regulation of fibronectin-dependent immature T-cell migration|regulation of fibronectin-dependent immature T lymphocyte migration|regulation of fibronectin-dependent thymic lymphocyte migration|regulation of fibronectin-dependent immature T-lymphocyte migration							mah	2011-02-23T01:38:08Z					biological_process											owl:Class	
GO:0032754	biolink:NamedThing	positive regulation of interleukin-5 production	Any process that activates or increases the frequency, rate, or extent of interleukin-5 production.	tmpzr1t_l9r_go_relaxed.owl	up regulation of interleukin-5 production|positive regulation of interleukin-5 biosynthetic process|stimulation of interleukin-5 production|activation of interleukin-5 production|positive regulation of IL-5 production|positive regulation of interleukin-5 secretion|up-regulation of interleukin-5 production|upregulation of interleukin-5 production											GO:2000664|GO:0045407		biological_process											owl:Class	
GO:1905844	biolink:NamedThing	negative regulation of cellular response to gamma radiation	Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to gamma radiation.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of cellular response to gamma ray|negative regulation of cellular response to gamma-ray photon|down-regulation of cellular response to gamma radiation|downregulation of cellular response to gamma ray|inhibition of cellular response to gamma radiation|inhibition of cellular response to gamma-ray photon|inhibition of cellular response to gamma ray|downregulation of cellular response to gamma-ray photon|down regulation of cellular response to gamma ray|down-regulation of cellular response to gamma-ray photon|down regulation of cellular response to gamma-ray photon|down regulation of cellular response to gamma radiation|downregulation of cellular response to gamma radiation|negative regulation of cellular response to gamma ray							rz	2017-01-19T10:24:48Z					biological_process											owl:Class	
GO:0005940	biolink:NamedThing	septin ring	A tight ring-shaped structure that forms in the division plane at the site of cytokinesis; composed of members of the conserved family of filament-forming proteins called septins as well as septin-associated proteins. This type of septin structure is observed at the bud neck of budding fungal cells, at the site of cell division in animal cells, at the junction between the mother cell and a pseudohyphal projection, and also within hyphae of filamentous fungi at sites where a septum will form.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Septin_ring							GO:0030481		cellular_component											owl:Class	
GO:0060300	biolink:NamedThing	regulation of cytokine activity	Any process that modulates the rate, frequency or extent of the activity of a molecule that controls the survival, growth, differentiation and effector function of tissues and cells.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0031739	biolink:NamedThing	cholecystokinin receptor binding	Binding to a cholecystokinin receptor.	tmpzr1t_l9r_go_relaxed.owl	cholecystokinin receptor ligand													molecular_function											owl:Class	
GO:2001061	biolink:NamedThing	D-glycero-D-manno-heptose 7-phosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of a D-glycero-D-manno-heptose 7-phosphate.	tmpzr1t_l9r_go_relaxed.owl	D-glycero-D-manno-heptose 7-phosphate biosynthesis				UniPathway:UPA00041			jl	2011-09-09T03:29:08Z					biological_process											owl:Class	
GO:2001284	biolink:NamedThing	regulation of BMP secretion	Any process that modulates the frequency, rate or extent of BMP secretion.	tmpzr1t_l9r_go_relaxed.owl	regulation of BMP protein secretion|regulation of bone morphogenetic protein secretion							bf	2011-12-15T02:15:28Z					biological_process											owl:Class	
GO:0060933	biolink:NamedThing	His-Purkinje system cell development	The process whose specific outcome is the progression of a His-Purkinje cell over time, from its formation to the mature state. These cells form the fibers that regulate cardiac muscle contraction in the ventricles.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-09-29T01:15:02Z					biological_process											owl:Class	
GO:0102359	biolink:NamedThing	daphnetin 4-O-beta-glucosyltransferase activity	Catalysis of the reaction: UDP-alpha-D-glucose + 7,8-dihydroxycoumarin <=> UDP + 4-O- beta -D-glucosyl-daphnetin + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-13450|EC:2.4.1.126									molecular_function											owl:Class	
GO:0075509	biolink:NamedThing	endocytosis involved in viral entry into host cell	Any endocytosis that is involved in the uptake of a virus into a host cell.	tmpzr1t_l9r_go_relaxed.owl	viral penetration via endocytosis followed by endosome disruption|viral entry into host cell via endocytosis|virus endocytosis by host				VZ:977			jl	2011-07-27T11:06:34Z					biological_process											owl:Class	
GO:0048368	biolink:NamedThing	lateral mesoderm development	The process whose specific outcome is the progression of the lateral mesoderm over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl	lateral plate mesoderm development													biological_process											owl:Class	
GO:0018186	biolink:NamedThing	peroxidase-heme linkage	The covalent linkage of heme to peroxidase.	tmpzr1t_l9r_go_relaxed.owl	peroxidase-haem linkage				RESID:AA0280|RESID:AA0279									biological_process											owl:Class	
GO:0020010	biolink:NamedThing	conoid	A spiral cytoskeletal structure located at the apical end of the apical complex in some apicomplexan parasites. Fibers form a left-handed spiral, and are comprised of tubulin protofilaments organized in a ribbon-like structure that differs from the conventional tubular structure characteristic of microtubules.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0004997	biolink:NamedThing	thyrotropin-releasing hormone receptor activity	Combining with thyrotropin-releasing hormone to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0006033	biolink:NamedThing	chitin localization	A process in which chitin is transported to, or maintained in, a specific location.	tmpzr1t_l9r_go_relaxed.owl	chitin localisation|establishment and maintenance of chitin localization													biological_process											owl:Class	
GO:0033037	biolink:NamedThing	polysaccharide localization	Any process in which a polysaccharide is transported to, or maintained in, a specific location.	tmpzr1t_l9r_go_relaxed.owl	polysaccharide localisation													biological_process											owl:Class	
GO:0004859	biolink:NamedThing	phospholipase inhibitor activity	Binds to and stops, prevents or reduces the activity of a phospholipase, an enzyme that catalyzes of the hydrolysis of a phospholipid.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0052170	biolink:NamedThing	suppression by symbiont of host innate immune response	Any process in which a symbiont stops, prevents, or reduces the frequency, rate or extent of the innate immune response of the host organism, the host's first line of defense against infection. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	down regulation by symbiont of host innate immunity|negative regulation by symbiont of host innate immunity|inhibition by symbiont of host innate immunity|negative regulation of host innate immune response|negative regulation by symbiont of host innate immune response|down-regulation by symbiont of host innate immunity|downregulation by symbiont of host innate immunity|negative regulation of innate immune response in other organism											GO:0052309		biological_process											owl:Class	
GO:0052167	biolink:NamedThing	modulation by symbiont of host innate immune response	Any process in which a symbiont modulates the frequency, rate or extent of the innate immune response of the host organism; the innate immune response is the host's first line of defense against infection. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	modulation by organism of innate immune response in other organism involved in symbiotic interaction|modulation of host innate immune response|modulation by symbiont of host innate immunity											GO:0052306		biological_process											owl:Class	
GO:0010036	biolink:NamedThing	response to boron-containing substance	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a boron-containing substance stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to boron													biological_process											owl:Class	
GO:0010182	biolink:NamedThing	sugar mediated signaling pathway	The process in which a change in the level of a mono- or disaccharide such as glucose, fructose or sucrose triggers the expression of genes controlling metabolic and developmental processes.	tmpzr1t_l9r_go_relaxed.owl	sugar mediated signalling													biological_process											owl:Class	
GO:1902997	biolink:NamedThing	negative regulation of neurofibrillary tangle assembly	Any process that stops, prevents or reduces the frequency, rate or extent of neurofibrillary tangle assembly.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of star-shaped neurofibrillary tangle formation|negative regulation of flame-shaped neurofibrillary tangle assembly|down regulation of flame-shaped neurofibrillary tangle assembly|inhibition of flame-shaped neurofibrillary tangle formation|down regulation of star-shaped neurofibrillary tangle assembly|down-regulation of flame-shaped neurofibrillary tangle assembly|inhibition of flame-shaped neurofibrillary tangle assembly|down regulation of star-shaped neurofibrillary tangle formation|inhibition of neurofibrillary tangle assembly|down regulation of flame-shaped neurofibrillary tangle formation|inhibition of star-shaped neurofibrillary tangle formation|downregulation of flame-shaped neurofibrillary tangle assembly|down-regulation of star-shaped neurofibrillary tangle assembly|down-regulation of neurofibrillary tangle formation|down-regulation of star-shaped neurofibrillary tangle formation|negative regulation of star-shaped neurofibrillary tangle assembly|downregulation of star-shaped neurofibrillary tangle formation|downregulation of neurofibrillary tangle formation|down-regulation of flame-shaped neurofibrillary tangle formation|inhibition of star-shaped neurofibrillary tangle assembly|downregulation of flame-shaped neurofibrillary tangle formation|downregulation of star-shaped neurofibrillary tangle assembly|down-regulation of neurofibrillary tangle assembly|downregulation of neurofibrillary tangle assembly|down regulation of neurofibrillary tangle formation|down regulation of neurofibrillary tangle assembly|negative regulation of neurofibrillary tangle formation|inhibition of neurofibrillary tangle formation|negative regulation of flame-shaped neurofibrillary tangle formation							sjp	2014-05-08T15:44:33Z					biological_process											owl:Class	
GO:0004750	biolink:NamedThing	ribulose-phosphate 3-epimerase activity	Catalysis of the reaction: D-ribulose 5-phosphate = D-xylulose 5-phosphate.	tmpzr1t_l9r_go_relaxed.owl	D-ribulose-5-phosphate epimerase activity|ribulose 5-phosphate 3-epimerase activity|phosphoketopentose 3-epimerase activity|D-xylulose-5-phosphate 3-epimerase activity|D-ribulose-5-phosphate 3-epimerase activity|D-ribulose-5-P 3-epimerase activity|D-ribulose phosphate-3-epimerase activity|phosphoketopentose epimerase activity|xylulose phosphate 3-epimerase activity|erythrose-4-phosphate isomerase activity|phosphoribulose epimerase activity|pentose-5-phosphate 3-epimerase activity|erythrose-4-phosphate epimerase activity|D-ribulose 5-phosphate epimerase activity				EC:5.1.3.1|Reactome:R-HSA-199803|KEGG_REACTION:R01529|RHEA:13677|Reactome:R-HSA-71303|MetaCyc:RIBULP3EPIM-RXN									molecular_function											owl:Class	
GO:0003857	biolink:NamedThing	3-hydroxyacyl-CoA dehydrogenase activity	Catalysis of the reaction: (S)-3-hydroxyacyl-CoA + NAD+ = 3-oxoacyl-CoA + NADH + H(+).	tmpzr1t_l9r_go_relaxed.owl	3-oxoacyl-thioester reductase activity|beta-hydroxyacylcoenzyme A dehydrogenase activity|beta-hydroxyacyl-coenzyme A synthetase activity|beta-hydroxyacyl dehydrogenase activity|L-3-hydroxyacyl coenzyme A dehydrogenase activity|L-3-hydroxyacyl CoA dehydrogenase activity|beta-keto-reductase activity|beta-hydroxybutyrylcoenzyme A dehydrogenase activity|beta-ketoacyl-CoA reductase				Reactome:R-HSA-70837|Reactome:R-HSA-390251|Reactome:R-HSA-77342|Reactome:R-HSA-77312|Reactome:R-HSA-77254|Reactome:R-HSA-77303|Reactome:R-HSA-193508|UM-BBD_enzymeID:e0664|Reactome:R-HSA-77283|Reactome:R-HSA-77323|Reactome:R-HSA-193455|RHEA:22432|Reactome:R-HSA-508369|Reactome:R-HSA-389995|EC:1.1.1.35|Reactome:R-HSA-77331|Reactome:R-HSA-6809264|MetaCyc:OHACYL-COA-DEHYDROG-RXN	See also 'long-chain-3-hydroxyacyl-CoA dehydrogenase activity ; GO:0016509'.								molecular_function											owl:Class	
GO:0047564	biolink:NamedThing	3-hydroxycyclohexanone dehydrogenase activity	Catalysis of the reaction: 3-hydroxycyclohexanone + A = AH(2) + cyclohexane-1,3-dione.	tmpzr1t_l9r_go_relaxed.owl	3-hydroxycyclohexanone:acceptor 1-oxidoreductase activity				RHEA:15905|EC:1.1.99.26|KEGG_REACTION:R03212|MetaCyc:3-HYDROXYCYCLOHEXANONE-DEHYDROGENASE-RXN									molecular_function											owl:Class	
GO:0047960	biolink:NamedThing	glycine dehydrogenase activity	Catalysis of the reaction: glycine + H2O + NAD+ = glyoxylate + NH3 + NADH.	tmpzr1t_l9r_go_relaxed.owl	glycine:NAD+ oxidoreductase (deaminating)				EC:1.4.1.10|RHEA:15721|MetaCyc:GLYCINE-DEHYDROGENASE-RXN									molecular_function											owl:Class	
GO:0051164	biolink:NamedThing	L-xylitol metabolic process	The chemical reactions and pathways involving L-xylitol, a five-carbon sugar alcohol derived from xylose by reduction of the carbonyl group. It is as sweet as sucrose and is used as a noncariogenic sweetner and as a sugar substitute in diabetic diets.	tmpzr1t_l9r_go_relaxed.owl	L-xylitol metabolism													biological_process											owl:Class	
GO:0005143	biolink:NamedThing	interleukin-12 receptor binding	Binding to an interleukin-12 receptor.	tmpzr1t_l9r_go_relaxed.owl	IL-12|interleukin-12 receptor ligand													molecular_function											owl:Class	
GO:0033882	biolink:NamedThing	choloyl-CoA hydrolase activity	Catalysis of the reaction: choloyl-CoA + H2O = cholate + CoA.	tmpzr1t_l9r_go_relaxed.owl	choloyl-coenzyme A thioesterase activity|peroxisomal acyl-CoA thioesterase 2 activity|chenodeoxycholoyl-coenzyme A thioesterase activity|PTE-2				RHEA:14541|EC:3.1.2.27|MetaCyc:3.1.2.27-RXN									molecular_function											owl:Class	
GO:2000419	biolink:NamedThing	regulation of eosinophil extravasation	Any process that modulates the frequency, rate or extent of eosinophil extravasation.	tmpzr1t_l9r_go_relaxed.owl								mah	2011-02-23T01:46:47Z					biological_process											owl:Class	
GO:0034582	biolink:NamedThing	3-hydroxy-4-methyloctanoyl-CoA dehydrogenase activity	Catalysis of the reaction: 3-hydroxy-4-methyloctanoyl-CoA = 4-methyl-3-oxooctanoyl-CoA + 2 H+ + 2 e-.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0926									molecular_function											owl:Class	
GO:2000403	biolink:NamedThing	positive regulation of lymphocyte migration	Any process that activates or increases the frequency, rate or extent of lymphocyte migration.	tmpzr1t_l9r_go_relaxed.owl								mah	2011-02-23T10:46:06Z					biological_process											owl:Class	
GO:0018668	biolink:NamedThing	3-hydroxybenzoate 4-monooxygenase activity	Catalysis of the reaction: 3-hydroxybenzoate + H(+) + NADPH + O(2) = 3,4-dihydroxybenzoate + H(2)O + NADP(+).	tmpzr1t_l9r_go_relaxed.owl	3-hydroxybenzoate 4-hydroxylase activity|3-hydroxybenzoate,NADPH:oxygen oxidoreductase (4-hydroxylating)				KEGG_REACTION:R01628|UM-BBD_reactionID:r0153|EC:1.14.13.23|RHEA:11480|MetaCyc:3-HYDROXYBENZOATE-4-MONOOXYGENASE-RXN									molecular_function											owl:Class	
GO:0009719	biolink:NamedThing	response to endogenous stimulus	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus arising within the organism.	tmpzr1t_l9r_go_relaxed.owl						Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.								biological_process											owl:Class	
GO:1903328	biolink:NamedThing	positive regulation of tRNA metabolic process	Any process that activates or increases the frequency, rate or extent of tRNA metabolic process.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of tRNA metabolism|up regulation of tRNA metabolic process|positive regulation of tRNA metabolism|upregulation of tRNA metabolism|up-regulation of tRNA metabolic process|up regulation of tRNA metabolism|upregulation of tRNA metabolic process|activation of tRNA metabolism|activation of tRNA metabolic process							vw	2014-08-18T13:09:06Z					biological_process											owl:Class	
GO:0042461	biolink:NamedThing	photoreceptor cell development	Development of a photoreceptor, a cell that responds to incident electromagnetic radiation, particularly visible light.	tmpzr1t_l9r_go_relaxed.owl	photoreceptor morphogenesis											GO:0046531		biological_process											owl:Class	
GO:0016984	biolink:NamedThing	ribulose-bisphosphate carboxylase activity	Catalysis of the reaction: 2 (2R)-3-phosphoglycerate + 2 H+ = CO2 + D-ribulose 1,5-bisphosphate + H2O.	tmpzr1t_l9r_go_relaxed.owl	ribulose 1,5-bisphosphate carboxylase/oxygenase activity|ribulose diphosphate carboxylase/oxygenase activity|RuBisCO activity|RuBP carboxylase activity|D-ribulose 1,5-diphosphate carboxylase activity|D-ribulose-1,5-bisphosphate carboxylase activity|ribulose 1,5-diphosphate carboxylase/oxygenase activity|ribulose bisphosphate carboxylase/oxygenase activity|ribulose diphosphate carboxylase activity|ribulose 1,5-bisphosphate carboxylase activity|carboxydismutase activity|ribulose 1,5-diphosphate carboxylase activity|diphosphoribulose carboxylase activity				RHEA:23124|MetaCyc:RIBULOSE-BISPHOSPHATE-CARBOXYLASE-RXN|EC:4.1.1.39									molecular_function											owl:Class	
GO:0045645	biolink:NamedThing	positive regulation of eosinophil differentiation	Any process that activates or increases the frequency, rate or extent of eosinophil differentiation.	tmpzr1t_l9r_go_relaxed.owl	up regulation of eosinophil differentiation|up-regulation of eosinophil differentiation|activation of eosinophil differentiation|stimulation of eosinophil differentiation|upregulation of eosinophil differentiation													biological_process											owl:Class	
GO:0022839	biolink:NamedThing	ion gated channel activity	Enables the transmembrane transfer of a solute by a channel that opens in response to a specific ion stimulus.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0061666	biolink:NamedThing	UFM1 ligase activity	Catalysis of the transfer of UFM1 to a substrate protein via the reaction X-UFM1 + S --> X + S-UFM1, where X is either an E2 or E3 enzyme, the X-UFM1 linkage is a thioester bond, and the S-UFM1 linkage is an isopeptide bond between the C-terminal amino acid of UFM1 and the epsilon-amino group of lysine residues in the substrate.	tmpzr1t_l9r_go_relaxed.owl	E3							dph	2014-11-06T14:02:37Z					molecular_function											owl:Class	
GO:0080153	biolink:NamedThing	negative regulation of reductive pentose-phosphate cycle	Any process that stops, prevents, or reduces the frequency, rate or extent of the reductive pentose-phosphate cycle.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of Calvin cycle|negative regulation of C3 photosynthesis							dhl	2010-07-01T02:55:27Z					biological_process											owl:Class	
GO:0080152	biolink:NamedThing	regulation of reductive pentose-phosphate cycle	Any process that modulates the frequency, rate or extent of reductive pentose-phosphate cycle.	tmpzr1t_l9r_go_relaxed.owl	regulation of C3 photosynthesis|regulation of Calvin cycle							dhl	2010-07-01T02:49:55Z					biological_process											owl:Class	
GO:0062104	biolink:NamedThing	pumilio-response element binding	Binding to a region of RNA containing a Pumilio-response element element. The consensus sequence for the element is UGUAAAUA.	tmpzr1t_l9r_go_relaxed.owl	PRE binding							dph	2019-01-11T13:38:26Z					molecular_function											owl:Class	
GO:0140522	biolink:NamedThing	fusogenic activity	The activity of joining two lipid bilayers to form a single membrane.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/19942						pg	2020-09-24T09:45:21Z					molecular_function											owl:Class	
GO:0043589	biolink:NamedThing	skin morphogenesis	The process in which the anatomical structures of the skin are generated and organized. The skin is the external membranous integument of an animal. In vertebrates the skin generally consists of two layers, an outer nonsensitive and nonvascular epidermis (cuticle or skarfskin) composed of cells which are constantly growing and multiplying in the deeper, and being thrown off in the superficial layers, as well as an inner, sensitive and vascular dermis (cutis, corium or true skin) composed mostly of connective tissue.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:2000827	biolink:NamedThing	mitochondrial RNA surveillance	The set of processes involved in identifying and degrading defective or aberrant RNAs that takes place in the mitochondrion.	tmpzr1t_l9r_go_relaxed.owl	RNA surveillance in mitochondria|RNA quality control in mitochondria|RNA quality control in mitochondrion|aberrant RNA catabolic process in mitochondrion|aberrant RNA catabolic process in mitochondria							bf	2011-07-20T01:33:23Z					biological_process											owl:Class	
GO:0140116	biolink:NamedThing	fluoride export across plasma membrane	The directed movement of fluoride ions from inside of a cell, across the plasma membrane and into the extracellular region.	tmpzr1t_l9r_go_relaxed.owl								pg	2017-10-24T14:51:01Z					biological_process											owl:Class	
GO:1903424	biolink:NamedThing	fluoride transmembrane transport	The process in which fluoride is transported across a membrane.	tmpzr1t_l9r_go_relaxed.owl	transmembrane fluoride transport|fluoride membrane transport							mcc	2014-09-09T21:21:01Z					biological_process											owl:Class	
GO:0072505	biolink:NamedThing	divalent inorganic anion homeostasis	Any process involved in the maintenance of an internal steady state of divalent inorganic anions within an organism or cell.	tmpzr1t_l9r_go_relaxed.owl						Note that this term was split from 'di-, tri-valent inorganic anion homeostasis ; GO:0055061' (sibling term 'trivalent inorganic anion homeostasis' ; GO:0072506').		mah	2010-12-16T01:39:00Z					biological_process											owl:Class	
GO:2000010	biolink:NamedThing	positive regulation of protein localization to cell surface	Any process that activates or increases the frequency, rate or extent of protein localization to the cell surface.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of protein localisation at cell surface|positive regulation of protein localization at cell surface							jl	2010-08-04T01:43:56Z					biological_process											owl:Class	
GO:2000008	biolink:NamedThing	regulation of protein localization to cell surface	Any process that modulates the frequency, rate or extent of protein localization to the cell surface.	tmpzr1t_l9r_go_relaxed.owl	regulation of protein localization at cell surface|regulation of protein localisation at cell surface							jl	2010-08-04T01:43:48Z					biological_process											owl:Class	
GO:2000237	biolink:NamedThing	positive regulation of tRNA processing	Any process that activates or increases the frequency, rate or extent of tRNA processing.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of tRNA maturation							mah	2010-11-10T12:15:17Z					biological_process											owl:Class	
GO:0001733	biolink:NamedThing	galactosylceramide sulfotransferase activity	Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + a galactosylceramide = adenosine 3',5'-bisphosphate + a galactosylceramidesulfate.	tmpzr1t_l9r_go_relaxed.owl	3'-phosphoadenylyl-sulfate:galactosylceramide 3'-sulfotransferase activity|3'-phosphoadenosine-5'-phosphosulfate-cerebroside sulfotransferase activity|galactosylceramide sulphotransferase activity|GSase|glycosphingolipid sulfotransferase activity|galactocerebroside sulfotransferase activity|cerebroside sulfotransferase activity|glycolipid sulfotransferase activity|galactolipid sulfotransferase activity				EC:2.8.2.11|RHEA:43304|MetaCyc:GALACTOSYLCERAMIDE-SULFOTRANSFERASE-RXN									molecular_function											owl:Class	
GO:0050694	biolink:NamedThing	galactose 3-O-sulfotransferase activity	Catalysis of the reaction: N-acetyllactosamine + 3'-phosphoadenosine 5'-phosphosulfate = 3-sulfo-N-acetyllactosamine + adenosine 3',5'-bisphosphate. N-acetyllactosamine residues are found in a number of different carbohydrate types. N-acetyllactosamine can also be written as Gal-beta-(1,4)-GlcNAc.	tmpzr1t_l9r_go_relaxed.owl	galactose 3-O-sulphotransferase activity|Gal-3-O-sulfotransferase activity													molecular_function											owl:Class	
GO:0033164	biolink:NamedThing	glycolipid 1,6-alpha-mannosyltransferase activity	Catalysis of the transfer of an alpha-D-mannosyl residue from GDP-mannose into lipid-linked oligosaccharide, forming an alpha-(1->6)-D-mannosyl-D-mannose linkage.	tmpzr1t_l9r_go_relaxed.owl	GDP-mannose:oligosaccharide 6-alpha-D-mannosyltransferase activity|GDP-mannose:glycolipid 1,6-alpha-D-mannosyltransferase activity|initiation-specific alpha-1,6-mannosyltransferase activity|glycolipid 6-alpha-mannosyltransferase activity|GDP-mannose:oligosaccharide 1,6-alpha-D-mannosyltransferase activity				MetaCyc:2.4.1.232-RXN|EC:2.4.1.232									molecular_function											owl:Class	
GO:0000009	biolink:NamedThing	alpha-1,6-mannosyltransferase activity	Catalysis of the transfer of a mannose residue to an oligosaccharide, forming an alpha-(1->6) linkage.	tmpzr1t_l9r_go_relaxed.owl	1,6-alpha-mannosyltransferase activity				EC:2.4.1.232|Reactome:R-HSA-449718									molecular_function											owl:Class	
GO:0032218	biolink:NamedThing	riboflavin transport	The directed movement of riboflavin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Riboflavin (vitamin B2) is a water-soluble B-complex vitamin, converted in the cell to FMN and FAD, cofactors required for the function of flavoproteins.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0047351	biolink:NamedThing	guanosine-triphosphate guanylyltransferase activity	Catalysis of the reaction: 2 GTP = P(1),P(4)-bis(5'-guanosyl) tetraphosphate + diphosphate + H(+).	tmpzr1t_l9r_go_relaxed.owl	GTP:GTP guanylyltransferase activity				RHEA:18153|MetaCyc:2.7.7.45-RXN|EC:2.7.7.45|KEGG_REACTION:R00012									molecular_function											owl:Class	
GO:0042322	biolink:NamedThing	negative regulation of circadian sleep/wake cycle, REM sleep	Any process that stops, prevents or reduces the duration or quality of rapid eye movement (REM) sleep.	tmpzr1t_l9r_go_relaxed.owl	down regulation of circadian sleep/wake cycle, REM sleep|inhibition of circadian sleep/wake cycle, REM sleep|downregulation of circadian sleep/wake cycle, REM sleep|negative regulation of REM sleep|down-regulation of circadian sleep/wake cycle, REM sleep													biological_process											owl:Class	
GO:0102666	biolink:NamedThing	indole-3-acetyl-beta-4-D-glucose hydrolase activity	Catalysis of the reaction: indole-3-acetyl-beta-4-D-glucose + H2O <=> H+ + indole-3-acetate + beta-D-glucose.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-3164									molecular_function											owl:Class	
GO:1990408	biolink:NamedThing	calcitonin gene-related peptide receptor signaling pathway	A series of molecular signals initiated by an extracellular calcitonin gene-related peptide (CGRP) combining with a calcitonin gene-related peptide receptor on the surface of the target cell. Calcitonin gene-related peptide receptors may form dimers, trimers or tetramers.	tmpzr1t_l9r_go_relaxed.owl	calcitonin-gene-related peptide receptor signaling pathway|CGRP receptor signaling pathway|calcitonin-gene-related polypeptide receptor signaling pathway					An example of a protein that could be annotated to this term is CALCRL in human (Q16602) in PMID:10882736.		bhm	2014-07-02T14:32:37Z					biological_process											owl:Class	
GO:0097646	biolink:NamedThing	calcitonin family receptor signaling pathway	A series of molecular signals initiated by an extracellular member of the calcitonin family (e.g. adrenomedullin, adrenomedullin 2 (intermedin), amylin, calcitonin and calcitonin gene-related peptides (CGRPs)) combining with a calcitonin family receptor on the surface of the target cell. Calcitonin family receptors may form dimers, trimers or tetramers; adrenomedullin and amylin receptors have only been observed as dimers so far.	tmpzr1t_l9r_go_relaxed.owl	calcitonin family receptor signalling pathway							pr	2014-09-09T17:48:05Z					biological_process											owl:Class	
GO:0072126	biolink:NamedThing	positive regulation of glomerular mesangial cell proliferation	Any process that increases the frequency, rate or extent of glomerular mesangial cell proliferation.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-02-22T01:49:31Z					biological_process											owl:Class	
GO:0071486	biolink:NamedThing	cellular response to high light intensity	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a high light intensity stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-12-18T02:13:23Z					biological_process											owl:Class	
GO:0001609	biolink:NamedThing	G protein-coupled adenosine receptor activity	Combining with adenosine and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.	tmpzr1t_l9r_go_relaxed.owl	G-protein-coupled A1 adenosine receptor activity|G protein coupled A2A adenosine receptor activity|adenosine receptor activity, G protein coupled|G-protein-coupled A2B adenosine receptor activity|G protein coupled A2B adenosine receptor activity|A2A adenosine receptor activity, G-protein coupled|A3 adenosine receptor activity, G protein coupled|G protein coupled A3 adenosine receptor activity|A3 adenosine receptor activity, G-protein coupled|A1 adenosine receptor activity, G protein coupled|A1 adenosine receptor activity, G-protein coupled|A2B adenosine receptor activity, G-protein coupled|P1 receptor|adenosine nucleotide receptor|G-protein-coupled A3 adenosine receptor activity|G-protein-coupled A2A adenosine receptor activity|A2A adenosine receptor activity, G protein coupled|A2B adenosine receptor activity, G protein coupled|G protein coupled adenosine receptor activity|G-protein coupled adenosine receptor activity|adenosine receptor activity, G-protein coupled|G protein coupled A1 adenosine receptor activity											GO:0001611|GO:0001610|GO:0001613|GO:0008501|GO:0001612		molecular_function											owl:Class	
GO:0043723	biolink:NamedThing	2,5-diamino-6-ribitylamino-4(3H)-pyrimidinone 5'-phosphate deaminase activity	Catalysis of the reaction: 2,5-diamino-6-(5-phospho-D-ribitylamino)pyrimidin-4(3H)-one + H2O = 5-amino-6-(5-phospho-D-ribosylamino)uracil + ammonia.	tmpzr1t_l9r_go_relaxed.owl	DRAP deaminase activity|2,5-diamino-6-(5-phosphoribitylamino)pyrimidin-4(3H)-one deaminase activity				MetaCyc:RXN-10058							GO:0017173		molecular_function											owl:Class	
GO:0072295	biolink:NamedThing	specification of metanephric distal tubule identity	The process in which the distal tubule of the metanephric nephron acquires its identity.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-04-09T04:01:42Z					biological_process											owl:Class	
GO:1902616	biolink:NamedThing	acyl carnitine transmembrane transport	The process in which acyl carnitine is transported across a membrane.	tmpzr1t_l9r_go_relaxed.owl	O-acylcarnitine transmembrane transport							pr	2014-01-10T11:07:30Z					biological_process											owl:Class	
GO:0090102	biolink:NamedThing	cochlea development	The progression of the cochlea over time from its formation to the mature structure. The cochlea is the snail-shaped portion of the inner ear that is responsible for the detection of sound.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-11-18T11:42:15Z					biological_process											owl:Class	
GO:0071308	biolink:NamedThing	cellular response to menaquinone	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a menaquinone (vitamin K2) stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to menatetrenone|cellular response to vitamin K2							mah	2009-12-10T04:37:08Z					biological_process											owl:Class	
GO:0032572	biolink:NamedThing	response to menaquinone	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a menaquinone (vitamin K2) stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to menatetrenone|response to vitamin K2													biological_process											owl:Class	
GO:1904071	biolink:NamedThing	presynaptic active zone assembly	The aggregation, arrangement and bonding together of a set of components to form a presynaptic active zone.  The presynaptic active zone is a specialized region of the plasma membrane and cell cortex of a presynaptic neuron; encompasses a region of the plasma membrane where synaptic vesicles dock and fuse, and a specialized cortical cytoskeletal matrix.	tmpzr1t_l9r_go_relaxed.owl	pre-synaptic active zone assembly|pre-synaptic active zone component formation|pre-synaptic active zone component assembly|presynaptic active zone formation|pre-synaptic active zone formation							pr	2015-03-20T10:36:27Z					biological_process											owl:Class	
GO:0031700	biolink:NamedThing	adrenomedullin receptor binding	Binding to an adrenomedullin receptor.	tmpzr1t_l9r_go_relaxed.owl	adrenomedullin receptor ligand													molecular_function											owl:Class	
GO:0015231	biolink:NamedThing	5-formyltetrahydrofolate transmembrane transporter activity	Enables the transfer of 5-formyltetrahydrofolate, the formylated derivative of tetrahydrofolate, from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	5-formyltetrahydrofolate transporter activity													molecular_function											owl:Class	
GO:0061519	biolink:NamedThing	macrophage homeostasis	The process of regulating the proliferation and elimination of macrophage cells such that the total number of myeloid cells within a whole or part of an organism is stable over time in the absence of an outside stimulus.	tmpzr1t_l9r_go_relaxed.owl								dph	2013-04-18T13:25:33Z					biological_process											owl:Class	
GO:0006848	biolink:NamedThing	pyruvate transport	The directed movement of pyruvate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1901195	biolink:NamedThing	positive regulation of formation of translation preinitiation complex	Any process that activates or increases the frequency, rate or extent of formation of translation preinitiation complex.	tmpzr1t_l9r_go_relaxed.owl	up regulation of formation of translation pre-initiation complex|activation of translation preinitiation complex assembly|up regulation of formation of translation preinitiation complex|up-regulation of formation of translation pre-initiation complex|activation of formation of translation pre-initiation complex|upregulation of formation of translation pre-initiation complex|up-regulation of formation of translation preinitiation complex|upregulation of formation of translation preinitiation complex|upregulation of translation preinitiation complex assembly|positive regulation of formation of translation pre-initiation complex|up-regulation of translation preinitiation complex assembly|positive regulation of translation preinitiation complex assembly|activation of formation of translation preinitiation complex|up regulation of translation preinitiation complex assembly							ss	2012-07-25T02:31:50Z					biological_process											owl:Class	
GO:0008386	biolink:NamedThing	cholesterol monooxygenase (side-chain-cleaving) activity	Catalysis of the reaction: cholesterol + reduced adrenal ferredoxin + O2 = pregnenolone + 4-methylpentanal + oxidized adrenal ferredoxin + H2O.	tmpzr1t_l9r_go_relaxed.owl	cholesterol 20-22-desmolase activity|cholesterol side-chain-cleaving enzyme activity|cholesterol,reduced-adrenal-ferredoxin:oxygen oxidoreductase (side-chain-cleaving)|Cyp11a1|steroid 20-22 desmolase activity|cytochrome p450(scc) activity|cholesterol desmolase activity|cytochrome P-450(scc) activity|steroid 20-22-lyase activity|enzymes, cholesterol side-chain-cleaving|cholesterol C20-22 desmolase activity|cholesterol side-chain cleavage enzyme activity|cytochrome P-450scc|desmolase, steroid 20-22|cholesterol C(20-22) desmolase activity|C27-side chain cleavage enzyme|cytochrome p450scc				Reactome:R-HSA-193101|RHEA:35739|Reactome:R-HSA-193054|EC:1.14.15.6|MetaCyc:1.14.15.6-RXN|Reactome:R-HSA-193065									molecular_function											owl:Class	
GO:0045795	biolink:NamedThing	positive regulation of cell volume	Any process that increases cell volume.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0036089	biolink:NamedThing	cleavage furrow formation	Generation of the cleavage furrow, a shallow groove in the cell surface near the old metaphase plate that marks the site of cytokinesis. This process includes the recruitment and localized activation of signals such as RhoA at the site of the future furrow to ensure that furrowing initiates at the correct site in the cell.	tmpzr1t_l9r_go_relaxed.owl	cleavage furrow positioning					Consider also annotating to 'establishment of contractile ring localization involved in cell cycle cytokinesis ; GO:0032188'.		bf	2012-01-10T02:41:03Z					biological_process											owl:Class	
GO:0047896	biolink:NamedThing	formaldehyde transketolase activity	Catalysis of the reaction: D-xylulose 5-phosphate + formaldehyde = glyceraldehyde 3-phosphate + glycerone.	tmpzr1t_l9r_go_relaxed.owl	dihydroxyacetone synthase activity|D-xylulose-5-phosphate:formaldehyde glycolaldehydetransferase activity|DHAS activity|glycerone synthase activity				MetaCyc:FORMALDEHYDE-TRANSKETOLASE-RXN|RHEA:24264|EC:2.2.1.3									molecular_function											owl:Class	
GO:0016415	biolink:NamedThing	octanoyltransferase activity	Catalysis of the transfer of an octanoyl (CH3-[CH2]6-CO-) group to an acceptor molecule.	tmpzr1t_l9r_go_relaxed.owl					EC:2.3.1.181									molecular_function											owl:Class	
GO:0098710	biolink:NamedThing	guanine import across plasma membrane	The directed movement of guanine from outside of a cell, across the plasma membrane and into the cytosol.	tmpzr1t_l9r_go_relaxed.owl	guanine import into cell							dph	2012-12-06T14:52:43Z			GO:0061489		biological_process											owl:Class	
GO:1903716	biolink:NamedThing	guanine transmembrane transport	The process in which guanine is transported across a membrane.	tmpzr1t_l9r_go_relaxed.owl								vw	2014-12-08T12:18:27Z					biological_process											owl:Class	
GO:1901817	biolink:NamedThing	beta-zeacarotene catabolic process	The chemical reactions and pathways resulting in the breakdown of beta-zeacarotene.	tmpzr1t_l9r_go_relaxed.owl	beta-zeacarotene degradation|beta-zeacarotene breakdown|beta-zeacarotene catabolism							yaf	2013-01-22T10:42:08Z					biological_process											owl:Class	
GO:0030943	biolink:NamedThing	mitochondrion targeting sequence binding	Binding to a mitochondrion targeting sequence, a specific peptide sequence that acts as a signal to localize the protein within the mitochondrion.	tmpzr1t_l9r_go_relaxed.owl	mitochondrial targeting sequence binding													molecular_function											owl:Class	
GO:0102507	biolink:NamedThing	cyanidin 3-O-glucoside 7-O-glucosyltransferase (hydroxybenzoly-glucose dependent) activity	Catalysis of the reaction: cyanidin 3-O-beta-D-glucoside betaine + 1-O-4-hydroxybenzoyl-beta-D-glucose <=> cyanidin 3,7-di-O-beta-D-glucoside betaine + 4-hydroxybenzoic acid + H+.	tmpzr1t_l9r_go_relaxed.owl					EC:2.4.1.300|MetaCyc:RXN-14434									molecular_function											owl:Class	
GO:0097332	biolink:NamedThing	response to antipsychotic drug	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antipsychotic drug stimulus. Antipsychotic drugs are agents that control agitated psychotic behaviour, alleviate acute psychotic states, reduce psychotic symptoms, and exert a quieting effect.	tmpzr1t_l9r_go_relaxed.owl								pr	2012-06-12T10:58:13Z					biological_process											owl:Class	
GO:0099530	biolink:NamedThing	G protein-coupled receptor activity involved in regulation of postsynaptic membrane potential	A G protein-coupled receptor activity occurring in the postsynaptic membrane that is part of a GPCR signaling pathway that positively regulates ion channel activity in the postsynaptic membrane.	tmpzr1t_l9r_go_relaxed.owl	G-protein coupled receptor activity involved in regulation of postsynaptic membrane potential													molecular_function											owl:Class	
GO:0002894	biolink:NamedThing	positive regulation of type II hypersensitivity	Any process that activates or increases the frequency, rate, or extent of type II hypersensitivity.	tmpzr1t_l9r_go_relaxed.owl	upregulation of type II hypersensitivity|up regulation of type II hypersensitivity|activation of type II hypersensitivity|stimulation of type II hypersensitivity|up-regulation of type II hypersensitivity													biological_process											owl:Class	
GO:0072398	biolink:NamedThing	signal transduction involved in cytokinesis checkpoint	A signal transduction process that contributes to a cytokinesis checkpoint.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-12-08T03:22:21Z			GO:0072419		biological_process											owl:Class	
GO:0043956	biolink:NamedThing	3-hydroxypropionyl-CoA dehydratase activity	Catalysis of the reaction: 3-hydroxypropionyl-CoA = acrylyl-CoA + H2O.	tmpzr1t_l9r_go_relaxed.owl	acetyl-coenzyme A synthetase|acetyl-coenzyme A synthetase/GroES-like domain|AMP-dependent synthetase and ligase:Enoyl-CoA hydratase/isomerase|AMP-dependent synthetase and ligase|enoyl-CoA hydratase/isomerase|3-hydroxy propionyl-CoA dehydratase activity				MetaCyc:RXN-6383|EC:4.2.1.116|RHEA:26518	Note that this function is one of the activities of the trifunctional enzyme propionyl-coenzyme A synthase. See PMID:11821399.								molecular_function											owl:Class	
GO:0046446	biolink:NamedThing	purine alkaloid metabolic process	The chemical reactions and pathways involving purine alkaloids, compounds derived from purine and composed of an N-containing double ring structure.	tmpzr1t_l9r_go_relaxed.owl	purine alkaloid metabolism													biological_process											owl:Class	
GO:0075312	biolink:NamedThing	negative regulation of sporangium development	Any process that stops, prevents, or reduces the frequency, rate or extent of sporangium development, a process that leads to the formation of sporangium, a single-celled or many-celled structure in which spores are produced, as in fungi, algae, mosses, and ferns, gymnosperms, angiosperms.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0044768	biolink:NamedThing	NMS complex assembly	The aggregation, arrangement and bonding together of a set of components to form an NMS complex. The NMS complex results from the association of two subcomplexes (known as MIND and Ndc80 in Schizosaccharomyces) and is required for kinetochore assembly.	tmpzr1t_l9r_go_relaxed.owl	NMS complex assembly involved in kinetochore assembly|Ndc80-MIND-Spc7 complex formation|KNL-1-Mis12-Ndc80 formation|KMN network assembly involved in chromosome segregation|KMN complex interaction involved in chromosome segregation|Ndc80-MIND-Spc7 complex assembly|KMN kinetochore network formation|NMS complex association involved in chromosome segregation|KNL-1-Mis12-Ndc80 assembly|KMN kinetochore network assembly|NMS complex formation							jl	2012-12-19T14:44:56Z					biological_process											owl:Class	
GO:0007064	biolink:NamedThing	mitotic sister chromatid cohesion	The cell cycle process in which the sister chromatids of a replicated chromosome are joined along the entire length of the chromosome, from their formation in S phase through metaphase during a mitotic cell cycle. This cohesion cycle is critical for high fidelity chromosome transmission.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0043625	biolink:NamedThing	delta DNA polymerase complex	A multimeric DNA polymerase enzyme complex which differs in composition amongst species; in humans it is a heterotetramer of four subunits of approximately 125, 50, 68 and 12kDa, while in S. cerevisiae, it has three different subunits which form a heterotrimer, and the active enzyme is a dimer of this heterotrimer. Functions in DNA replication, mismatch repair and excision repair.	tmpzr1t_l9r_go_relaxed.owl	delta-DNA polymerase complex											GO:0005659		cellular_component											owl:Class	
GO:0032610	biolink:NamedThing	interleukin-1 alpha production	The appearance of interleukin-1 alpha due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	tmpzr1t_l9r_go_relaxed.owl	interleukin-1 alpha secretion|IL-1 alpha production|interleukin-1 alpha biosynthetic process											GO:0050719|GO:0050703		biological_process											owl:Class	
GO:1904365	biolink:NamedThing	regulation of chemokinesis	Any process that modulates the frequency, rate or extent of chemokinesis.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-06-15T22:44:06Z					biological_process											owl:Class	
GO:0018614	biolink:NamedThing	ethylbenzene dioxygenase activity	Catalysis of the reaction: ethylbenzene + O2 + NADH + H+ = NAD+ + cis-2,3-dihydroxy-2,3-dihydroethylbenzene.	tmpzr1t_l9r_go_relaxed.owl					EC:1.14.12.-|UM-BBD_reactionID:r0247									molecular_function											owl:Class	
GO:0018153	biolink:NamedThing	isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine	The formation of an isopeptide cross-link between peptidyl-lysine and peptidyl-glutamine to produce N6-(L-isoglutamyl)-L-lysine.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0124									biological_process											owl:Class	
GO:0120115	biolink:NamedThing	Lsm2-8 complex	A heteroheptameric, nuclear protein complex composed of Lsm2, Lsm3, Lsm4, Lsm5, Lsm6, Lsm7, and Lsm8, or orthologs thereof, that selectively binds to snRNAs, in particular U6 or U6atac snRNAs, and also to unspliced transcripts localized within the nucleus.	tmpzr1t_l9r_go_relaxed.owl								krc	2017-11-06T18:56:22Z					cellular_component											owl:Class	
GO:0042660	biolink:NamedThing	positive regulation of cell fate specification	Any process that activates or enables a cell to adopt a specific fate.	tmpzr1t_l9r_go_relaxed.owl	stimulation of cell fate specification|up regulation of cell fate specification|up-regulation of cell fate specification|upregulation of cell fate specification|activation of cell fate specification													biological_process											owl:Class	
GO:1901778	biolink:NamedThing	pentalenolactone metabolic process	The chemical reactions and pathways involving pentalenolactone.	tmpzr1t_l9r_go_relaxed.owl	pentalenolactone metabolism							yaf	2013-01-16T09:49:38Z					biological_process											owl:Class	
GO:0071498	biolink:NamedThing	cellular response to fluid shear stress	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fluid shear stress stimulus. Fluid shear stress is the force acting on an object in a system where the fluid is moving across a solid surface.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-12-18T02:41:44Z					biological_process											owl:Class	
GO:0034405	biolink:NamedThing	response to fluid shear stress	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fluid shear stress stimulus. Fluid shear stress is the force acting on an object in a system where the fluid is moving across a solid surface.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1900888	biolink:NamedThing	negative regulation of pentadecane biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of pentadecane biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	down regulation of pentadecane biosynthetic process|down regulation of pentadecane anabolism|downregulation of pentadecane biosynthesis|inhibition of pentadecane biosynthesis|downregulation of pentadecane anabolism|inhibition of pentadecane anabolism|downregulation of pentadecane formation|inhibition of pentadecane synthesis|down regulation of pentadecane synthesis|downregulation of pentadecane synthesis|downregulation of pentadecane biosynthetic process|down-regulation of pentadecane biosynthesis|down-regulation of pentadecane anabolism|inhibition of pentadecane formation|down regulation of pentadecane biosynthesis|down-regulation of pentadecane formation|down-regulation of pentadecane biosynthetic process|down regulation of pentadecane formation|negative regulation of pentadecane formation|inhibition of pentadecane biosynthetic process|negative regulation of pentadecane biosynthesis|down-regulation of pentadecane synthesis|negative regulation of pentadecane anabolism|negative regulation of pentadecane synthesis							tt	2012-06-13T03:03:57Z					biological_process											owl:Class	
GO:0097253	biolink:NamedThing	beta-hydroxybutyrate transmembrane transporter activity	Enables the transfer of beta-hydroxybutyrate from one side of a membrane to the other. Beta-hydroxybutyrate is the conjugate base of (R)-3-hydroxybutyric acid.	tmpzr1t_l9r_go_relaxed.owl	(R)-3-hydroxybutyrate transmembrane transporter activity|3-hydroxybutanoic acid transmembrane transporter activity							pr	2012-03-05T01:22:37Z					molecular_function											owl:Class	
GO:0061664	biolink:NamedThing	Pup ligase activity	Catalysis of the transfer of Pup to a substrate protein via the reaction X-Pup + S --> X + S-Pup, where X is either an E2 or E3 enzyme, the X-Pup linkage is a thioester bond, and the S-Pup linkage is an isopeptide bond between the C-terminal amino acid of Pup and the epsilon-amino group of lysine residues in the substrate.	tmpzr1t_l9r_go_relaxed.owl	E3							dph	2014-11-06T13:59:09Z					molecular_function											owl:Class	
GO:0072496	biolink:NamedThing	Pup transferase activity	Catalysis of the transfer of Pup from one protein to another via the reaction X-Pup + Y --> Y-Pup + X, where both X-Pup and Y-Pup are covalent linkages.	tmpzr1t_l9r_go_relaxed.owl	Pup conjugating enzyme activity							mah	2010-12-15T11:58:13Z					molecular_function											owl:Class	
GO:0034700	biolink:NamedThing	allulose 6-phosphate 3-epimerase activity	Catalysis of the reaction: D-allulose 6-phosphate = D-fructose 6-phosphate.	tmpzr1t_l9r_go_relaxed.owl					RHEA:28426|MetaCyc:RXN0-304									molecular_function											owl:Class	
GO:0102904	biolink:NamedThing	germacrene C synthase activity	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = germacrene C + diphosphoric acid.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-8561|EC:4.2.3.60|RHEA:28302									molecular_function											owl:Class	
GO:0071216	biolink:NamedThing	cellular response to biotic stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biotic stimulus, a stimulus caused or produced by a living organism.	tmpzr1t_l9r_go_relaxed.owl	cellular response to biotic stress					Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.		mah	2009-12-03T01:09:08Z					biological_process											owl:Class	
GO:0098515	biolink:NamedThing	detection of low humidity stimulus involved in sensory perception	The series of events in which a low humidity stimulus is detected and converted into a molecular signal as a part of the sensory detection of low humidity.	tmpzr1t_l9r_go_relaxed.owl								dos	2013-09-25T14:24:29Z					biological_process											owl:Class	
GO:0098517	biolink:NamedThing	detection of low humidity	The series of events in which low humidity is detected and converted into a molecular signal.	tmpzr1t_l9r_go_relaxed.owl								dos	2013-09-25T14:27:18Z					biological_process											owl:Class	
GO:2001248	biolink:NamedThing	regulation of ammonia assimilation cycle	Any process that modulates the frequency, rate or extent of ammonia assimilation cycle.	tmpzr1t_l9r_go_relaxed.owl	regulation of glutamate metabolic process via glutamine and ammonia|regulation of glutamate metabolism via glutamine and ammonia							rl	2011-12-01T10:08:21Z					biological_process											owl:Class	
GO:1905590	biolink:NamedThing	fibronectin fibril organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a fibronectin fibril.	tmpzr1t_l9r_go_relaxed.owl								dph	2016-10-25T12:04:50Z					biological_process											owl:Class	
GO:0106257	biolink:NamedThing	glycerol-3-phosphate dehydrogenase [NADP+] activity	Catalysis of the reaction: sn-glycerol 3-phosphate + NADP+ = glycerone phosphate + NADH + H+.	tmpzr1t_l9r_go_relaxed.owl					RHEA:11096			hjd	2020-04-03T17:10:44Z					molecular_function											owl:Class	
GO:0047952	biolink:NamedThing	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity	Catalysis of the reaction: sn-glycerol 3-phosphate + NAD(P)+ = glycerone phosphate + NAD(P)H + H+.	tmpzr1t_l9r_go_relaxed.owl	glycerol-3-phosphate dehydrogenase (NAD(P)+) activity|L-glycerol-3-phosphate:NAD(P) oxidoreductase activity|sn-glycerol-3-phosphate:NAD(P)+ 2-oxidoreductase activity|glycerol phosphate dehydrogenase (nicotinamide adenine dinucleotide (phosphate)) activity				MetaCyc:GLYC3PDEHYDROGBIOSYN-RXN|EC:1.1.1.94|KEGG_REACTION:R00844			bf	2013-09-30T10:37:46Z			GO:0036439		molecular_function											owl:Class	
GO:1990819	biolink:NamedThing	actin fusion focus	A focus at the mating projection tip where the cell wall is degraded during conjugation with cellular fusion. Actin filaments form an aster-like structure from this location.	tmpzr1t_l9r_go_relaxed.owl								al	2015-08-10T16:52:15Z					cellular_component											owl:Class	
GO:0043313	biolink:NamedThing	regulation of neutrophil degranulation	Any process that modulates the frequency, rate, or extent of neutrophil degranulation.	tmpzr1t_l9r_go_relaxed.owl	regulation of neutrophil granule exocytosis													biological_process											owl:Class	
GO:1903562	biolink:NamedThing	microtubule bundle formation involved in mitotic spindle midzone assembly	Any microtubule bundle formation that is involved in spindle midzone assembly involved in mitosis.	tmpzr1t_l9r_go_relaxed.owl	microtubule bundle formation involved in mitotic spindle midzone formation|microtubule bundling involved in spindle midzone formation involved in mitosis|microtubule bundling involved in mitotic spindle midzone formation|microtubule bundling involved in spindle midzone assembly involved in mitosis|microtubule bundling involved in spindle midzone biogenesis involved in mitosis|microtubule bundle formation involved in spindle midzone assembly involved in mitosis|microtubule bundling involved in mitotic spindle midzone assembly							vw	2014-10-23T11:04:56Z					biological_process											owl:Class	
GO:0001578	biolink:NamedThing	microtubule bundle formation	A process that results in a parallel arrangement of microtubules.	tmpzr1t_l9r_go_relaxed.owl	microtubule bundling													biological_process											owl:Class	
GO:0031809	biolink:NamedThing	H3 histamine receptor binding	Binding to a H3 histamine receptor.	tmpzr1t_l9r_go_relaxed.owl	H3 histamine receptor ligand													molecular_function											owl:Class	
GO:0042176	biolink:NamedThing	regulation of protein catabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds.	tmpzr1t_l9r_go_relaxed.owl	regulation of protein catabolism|regulation of protein degradation|regulation of protein breakdown													biological_process											owl:Class	
GO:0090228	biolink:NamedThing	positive regulation of red or far-red light signaling pathway	Any process that increases the rate, frequency or extent of the red or far-red signaling pathway, the series of molecular signals initiated upon sensing by photoreceptor molecules of red light or far red light.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of phytochrome signaling pathway|positive regulation of red or far-red light signalling pathway							tb	2010-01-19T04:03:29Z					biological_process											owl:Class	
GO:0000049	biolink:NamedThing	tRNA binding	Binding to a transfer RNA.	tmpzr1t_l9r_go_relaxed.owl	base pairing with tRNA											GO:0000946		molecular_function											owl:Class	
GO:1900211	biolink:NamedThing	regulation of mesenchymal cell apoptotic process involved in metanephros development	Any process that modulates the frequency, rate or extent of mesenchymal cell apoptotic process involved in metanephros development.	tmpzr1t_l9r_go_relaxed.owl	regulation of mesenchymal cell apoptosis involved in metanephros development							yaf	2012-03-22T10:52:50Z					biological_process											owl:Class	
GO:0047610	biolink:NamedThing	acetylsalicylate deacetylase activity	Catalysis of the reaction: acetylsalicylate + H(2)O = acetate + H(+) + salicylate.	tmpzr1t_l9r_go_relaxed.owl	aspirin esterase activity|acetylsalicylic acid esterase activity|acetylsalicylate O-acetylhydrolase activity|aspirin hydrolase activity				EC:3.1.1.55|KEGG_REACTION:R02942|MetaCyc:ACETYLSALICYLATE-DEACETYLASE-RXN|RHEA:11752									molecular_function											owl:Class	
GO:0017189	biolink:NamedThing	N-terminal peptidyl-alanine acetylation	The acetylation of the N-terminal alanine of proteins; catalyzed by peptide alpha-N-acetyltransferase or other enzymes of this class, such as ribosomal-protein-alanine N-acetyltransferase.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0041	See also the molecular function terms 'peptide alpha-N-acetyltransferase activity ; GO:0004596' and 'ribosomal-protein-alanine N-acetyltransferase activity ; GO:0008999'.								biological_process											owl:Class	
GO:0046814	biolink:NamedThing	coreceptor-mediated virion attachment to host cell	The process by which a virion attaches to a host cell by binding to a co-receptor on the host cell surface.	tmpzr1t_l9r_go_relaxed.owl	virion attachment, binding of host cell surface coreceptor													biological_process											owl:Class	
GO:1903234	biolink:NamedThing	negative regulation of calcium ion-dependent exocytosis of neurotransmitter	Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion-dependent exocytosis of neurotransmitter.	tmpzr1t_l9r_go_relaxed.owl	down regulation of calcium ion-dependent exocytosis of neurotransmitter|inhibition of calcium ion-dependent exocytosis of neurotransmitter|down-regulation of calcium ion-dependent exocytosis of neurotransmitter|downregulation of calcium ion-dependent exocytosis of neurotransmitter					An example of this is Rab3gap1 in mouse (Q80UJ7) in PMID:16782817 (IMP)		pad	2014-07-31T11:54:40Z					biological_process											owl:Class	
GO:0018121	biolink:NamedThing	NAD(P)-asparagine ADP-ribosyltransferase activity	Catalysis of the reaction: NAD(P)+ + L-asparagine = nicotinamide + N2-(ADP-D-ribosyl)-L-asparagine.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0006111	biolink:NamedThing	regulation of gluconeogenesis	Any process that modulates the frequency, rate or extent of gluconeogenesis, the formation of glucose from noncarbohydrate precursors, such as pyruvate, amino acids and glycerol.	tmpzr1t_l9r_go_relaxed.owl	regulation of glucose biosynthesis|regulation of gluconeogenesis involved in cellular glucose homeostasis|regulation of glucose biosynthetic process							tb	2013-01-18T12:47:43Z			GO:0090526		biological_process											owl:Class	
GO:0042582	biolink:NamedThing	azurophil granule	Primary lysosomal granule found in neutrophil granulocytes. Contains a wide range of hydrolytic enzymes and is released into the extracellular fluid.	tmpzr1t_l9r_go_relaxed.owl	primary granule													cellular_component											owl:Class	
GO:0005766	biolink:NamedThing	primary lysosome	A lysosome before it has fused with a vesicle or vacuole.	tmpzr1t_l9r_go_relaxed.owl					NIF_Subcellular:sao1140587416									cellular_component											owl:Class	
GO:2000200	biolink:NamedThing	regulation of ribosomal subunit export from nucleus	Any process that modulates the frequency, rate or extent of ribosomal subunit export from nucleus.	tmpzr1t_l9r_go_relaxed.owl	regulation of ribosomal subunit export from cell nucleus|regulation of ribosomal subunit-nucleus export|regulation of ribosomal subunit transport from nucleus to cytoplasm|regulation of ribosomal subunit export out of nucleus|regulation of ribosome export from nucleus							mah	2010-10-26T10:44:27Z					biological_process											owl:Class	
GO:0085032	biolink:NamedThing	modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade	Any process in which an organism modulates the frequency, rate or extent of host NF-kappaB-mediated signal transduction pathways during the host defense response. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	modulation by symbiont of host NF-kappaB-mediated signal transduction pathway							jl	2010-07-27T02:13:37Z					biological_process											owl:Class	
GO:0005962	biolink:NamedThing	mitochondrial isocitrate dehydrogenase complex (NAD+)	Mitochondrial complex that possesses isocitrate dehydrogenase (NAD+) activity.	tmpzr1t_l9r_go_relaxed.owl						Note that this term represents a location and not a function; the activity possessed by this complex is mentioned in the definition for the purpose of describing and distinguishing the complex. The function of this complex is represented by the molecular function term 'isocitrate dehydrogenase (NAD+) activity ; GO:0004449'.								cellular_component											owl:Class	
GO:0072082	biolink:NamedThing	specification of proximal tubule identity	The process in which the proximal tubule of the kidney nephron acquires its identity.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-02-01T02:44:34Z					biological_process											owl:Class	
GO:0035469	biolink:NamedThing	determination of pancreatic left/right asymmetry	Determination of the asymmetric location of the pancreas with respect to the left and right halves of the organism.	tmpzr1t_l9r_go_relaxed.owl								bf	2010-04-22T10:47:15Z					biological_process											owl:Class	
GO:0008591	biolink:NamedThing	regulation of Wnt signaling pathway, calcium modulating pathway	Any process that modulates the frequency, rate or extent of the series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors leads to an increase in intracellular calcium and activation of protein kinase C (PKC).	tmpzr1t_l9r_go_relaxed.owl	regulation of frizzled-2 signalling pathway|regulation of frizzled-2 signaling pathway|regulation of Wnt receptor signaling pathway, calcium modulating pathway|regulation of Wnt-activated signaling pathway, calcium modulating pathway													biological_process											owl:Class	
GO:0052839	biolink:NamedThing	inositol diphosphate tetrakisphosphate kinase activity	Catalysis of the reaction: Catalysis of the reaction: ATP + inositol diphosphate tetrakisphosphate = ADP + inositol bisdiphosphate trisphosphate.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-1855193|Reactome:R-HSA-1855230			ai	2011-11-29T04:14:22Z					molecular_function											owl:Class	
GO:0110029	biolink:NamedThing	negative regulation of meiosis I	Any process that stops, prevents, or reduces the frequency, rate or extent of meiosis I, a cell cycle process comprising the steps by which a cell progresses through the first phase of meiosis, in which cells divide and homologous chromosomes are paired and segregated from each other, producing two daughter cells.	tmpzr1t_l9r_go_relaxed.owl								kmv	2017-07-12T18:47:33Z					biological_process											owl:Class	
GO:0018712	biolink:NamedThing	3-hydroxybutyryl-CoA thiolase activity	Catalysis of the reaction: 3-hydroxy-5-oxohexanoyl-CoA + CoASH = 3-hydroxybutyryl-CoA + acetyl-CoA.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0010|MetaCyc:R7-RXN									molecular_function											owl:Class	
GO:0010125	biolink:NamedThing	mycothiol biosynthetic process	The chemical reactions and pathways resulting in the formation of mycothiol, which consists of N-acetyl-L-cysteine linked to a pseudodisaccharide, D-glucosamine and myo-inositol. Mycothiol is produced in actinomycetes like mycobacteria and serves similar functions to glutathione.	tmpzr1t_l9r_go_relaxed.owl	mycothiol anabolism|mycothiol synthesis|mycothiol biosynthesis|mycothiol formation				MetaCyc:PWY1G-0									biological_process											owl:Class	
GO:1902101	biolink:NamedThing	positive regulation of metaphase/anaphase transition of cell cycle	Any process that activates or increases the frequency, rate or extent of metaphase/anaphase transition of cell cycle.	tmpzr1t_l9r_go_relaxed.owl	upregulation of metaphase/anaphase transition of cell cycle|activation of metaphase/anaphase transition of cell cycle|up regulation of metaphase/anaphase transition of cell cycle|up-regulation of metaphase/anaphase transition of cell cycle							jl	2013-05-02T12:45:30Z					biological_process											owl:Class	
GO:0050398	biolink:NamedThing	wax-ester hydrolase activity	Catalysis of the reaction: a wax ester + H2O = a long-chain alcohol + a long-chain carboxylate.	tmpzr1t_l9r_go_relaxed.owl	jojoba wax esterase|wax-ester acylhydrolase activity|WEH				MetaCyc:WAX-ESTER-HYDROLASE-RXN|RHEA:13577|EC:3.1.1.50									molecular_function											owl:Class	
GO:0004686	biolink:NamedThing	elongation factor-2 kinase activity	Catalysis of the reaction: ATP + [elongation factor 2] = ADP + [elongation factor 2] phosphate.	tmpzr1t_l9r_go_relaxed.owl	eEF2K|Ca/CaM-kinase III activity|EF2K|CaM kinase III activity|elongation factor 2 kinase activity|eEF2 kinase activity|eukaryotic elongation factor 2 kinase activity|eEF-2 kinase activity|calmodulin-dependent protein kinase III activity|STK19|ATP:elongation factor 2 phosphotransferase activity				EC:2.7.11.20|RHEA:21436|MetaCyc:2.7.11.20-RXN									molecular_function											owl:Class	
GO:0004683	biolink:NamedThing	calmodulin-dependent protein kinase activity	Calmodulin-dependent catalysis of the reactions: ATP + a protein serine = ADP + protein serine phosphate; and ATP + a protein threonine = ADP + protein threonine phosphate.	tmpzr1t_l9r_go_relaxed.owl	caldesmon kinase (phosphorylating) activity|ATP:protein phosphotransferase (Ca2+/calmodulin-dependent) activity|microtubule-associated protein 2 kinase activity|CaMKKalpha|calmodulin-dependent kinase II activity|CaMKKbeta|CAM PKII|multifunctional calcium- and calmodulin-regulated protein kinase activity|calcium/calmodulin-dependent protein kinase type II activity|calmodulin-dependent protein kinase I activity|CaM kinase activity|Ca2+/calmodulin-dependent protein kinase IV activity|Ca2+/calmodulin-dependent microtubule-associated protein 2 kinase activity|Ca2+/CaM-dependent kinase activity|Ca2+/calmodulin-dependent protein kinase II activity|ATP:caldesmon O-phosphotransferase activity|CaM-regulated serine/threonine kinase activity|Ca2+/calmodulin-dependent protein kinase kinase beta activity|CaMKII|calcium- and calmodulin-dependent protein kinase activity|multifunctional calcium/calmodulin regulated protein kinase activity|CaM kinase II activity|CaMKI|Ca2+/calmodulin-dependent protein kinase kinase activity|Ca2+/calmodulin-dependent protein kinase 1 activity|CaMKIV|calmodulin regulated protein kinase activity|STK20|Ca2+/calmodulin-dependent protein kinase activity|calcium/calmodulin-dependent protein kinase activity				EC:2.7.11.17|Reactome:R-HSA-9006992|Reactome:R-HSA-9617583|Reactome:R-HSA-111915|MetaCyc:2.7.11.17-RXN|Reactome:R-HSA-9619125|Reactome:R-HSA-442749|Reactome:R-HSA-111912|Reactome:R-HSA-9619783|Reactome:R-HSA-9618750|Reactome:R-HSA-9619355|Reactome:R-HSA-9619478|Reactome:R-HSA-416320|Reactome:R-HSA-9619367	These reactions require the presence of calcium-bound calmodulin.						GO:0004685|GO:0004688|GO:0004684		molecular_function											owl:Class	
GO:0004566	biolink:NamedThing	beta-glucuronidase activity	Catalysis of the reaction: a beta-D-glucuronoside + H2O = an alcohol + D-glucuronate.	tmpzr1t_l9r_go_relaxed.owl	ketodase activity|glucuronidase activity|exo-beta-D-glucuronidase activity|beta-D-glucuronoside glucuronosohydrolase activity|beta-glucuronide glucuronohydrolase activity				Reactome:R-HSA-9036068|RHEA:17633|Reactome:R-HSA-9036070|Reactome:R-HSA-2318373|Reactome:R-HSA-1678854|Reactome:R-HSA-2162227|EC:3.2.1.31|MetaCyc:BETA-GLUCURONID-RXN|Reactome:R-HSA-2162226									molecular_function											owl:Class	
GO:0071801	biolink:NamedThing	regulation of podosome assembly	Any process that modulates the frequency, rate or extent of podosome assembly.	tmpzr1t_l9r_go_relaxed.owl						Note that the assembly is regulated by several small GTPases of the Rab and Rho families.		mah	2010-09-03T01:34:29Z					biological_process											owl:Class	
GO:0019843	biolink:NamedThing	rRNA binding	Binding to a ribosomal RNA.	tmpzr1t_l9r_go_relaxed.owl	base pairing with rRNA											GO:0000944		molecular_function											owl:Class	
GO:0022855	biolink:NamedThing	protein-N(PI)-phosphohistidine-glucose phosphotransferase system transporter activity	Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + glucose(out) = protein histidine + glucose phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.	tmpzr1t_l9r_go_relaxed.owl	glucose PTS transporter activity													molecular_function											owl:Class	
GO:0070243	biolink:NamedThing	regulation of thymocyte apoptotic process	Any process that modulates the occurrence or rate of thymocyte death by apoptotic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of immature T cell apoptosis|regulation of thymocyte apoptosis					Note that a thymocyte is an immature T cell located in the thymus (CL:0000893).								biological_process											owl:Class	
GO:0000321	biolink:NamedThing	re-entry into mitotic cell cycle after pheromone arrest	The resumption of the mitotic cell division cycle by pheromone-arrested cells that have not mated. An example of this process is found in Saccharomyces cerevisiae.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0000320	biolink:NamedThing	re-entry into mitotic cell cycle	The resumption of the mitotic cell division cycle by cells that were in a quiescent or other non-dividing state.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0060167	biolink:NamedThing	regulation of adenosine receptor signaling pathway	Any process that modulates the frequency, rate or extent of the adenosine receptor signaling pathway. The adenosine receptor pathway is the series of molecular signals generated as a consequence of an adenosine receptor binding to one of its physiological ligands.	tmpzr1t_l9r_go_relaxed.owl	regulation of adenosine receptor signalling pathway													biological_process											owl:Class	
GO:0030160	biolink:NamedThing	synaptic receptor adaptor activity	The binding activity of a molecule that provides a physical support bridging a synaptic signaling receptor and a downstream signaling molecule.	tmpzr1t_l9r_go_relaxed.owl	postsynaptic density scaffold protein|GKAP/Homer scaffold protein|GKAP/Homer scaffold activity	https://github.com/geneontology/go-ontology/issues/18409												molecular_function											owl:Class	
GO:0030159	biolink:NamedThing	signaling receptor complex adaptor activity	The binding activity of a molecule that provides a physical support for the assembly of a multiprotein receptor signaling complex.	tmpzr1t_l9r_go_relaxed.owl	receptor signaling complex scaffold protein activity|receptor signaling complex adaptor activity|receptor signaling complex scaffold activity|receptor signalling complex scaffold activity|receptor signalling complex adaptor activity													molecular_function											owl:Class	
GO:0046692	biolink:NamedThing	sperm competition	Any process that contributes to the success of sperm fertilization in multiply-mated females.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Sperm_competition									biological_process											owl:Class	
GO:1903304	biolink:NamedThing	positive regulation of pyruvate kinase activity	Any process that activates or increases the frequency, rate or extent of pyruvate kinase activity.	tmpzr1t_l9r_go_relaxed.owl	up regulation of phosphoenolpyruvate kinase activity|up-regulation of phosphoenolpyruvate kinase activity|up-regulation of ATP:pyruvate 2-O-phosphotransferase activity|positive regulation of ATP:pyruvate 2-O-phosphotransferase activity|positive regulation of phosphoenol transphosphorylase activity|activation of phosphoenol transphosphorylase activity|upregulation of ATP:pyruvate 2-O-phosphotransferase activity|activation of phosphoenolpyruvate kinase activity|up-regulation of phosphoenol transphosphorylase activity|up regulation of phosphoenol transphosphorylase activity|upregulation of phosphoenol transphosphorylase activity|positive regulation of phosphoenolpyruvate kinase activity|upregulation of phosphoenolpyruvate kinase activity|upregulation of pyruvate kinase activity|activation of ATP:pyruvate 2-O-phosphotransferase activity|up regulation of pyruvate kinase activity|up-regulation of pyruvate kinase activity|activation of pyruvate kinase activity|up regulation of ATP:pyruvate 2-O-phosphotransferase activity							mr	2014-08-15T23:26:06Z					biological_process											owl:Class	
GO:0102696	biolink:NamedThing	cis-zeatin UDP glycosyltransferase activity	Catalysis of the reaction: UDP-alpha-D-glucose + cis-zeatin = H+ + 9-(alpha-D-glucosyl)-cis-zeatin + UDP.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-4734									molecular_function											owl:Class	
GO:0003108	biolink:NamedThing	negative regulation of the force of heart contraction by chemical signal	Any process which decreases the force of heart muscle contraction mediated by chemical signaling, hormonal, autocrine or paracrine.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of the force of heart muscle contraction by chemical signal													biological_process											owl:Class	
GO:0060398	biolink:NamedThing	regulation of growth hormone receptor signaling pathway	Any process that modulates the rate, frequency or extent of the growth hormone receptor signaling pathway. The growth hormone receptor signaling pathway is the series of molecular signals generated as a consequence of growth hormone receptor binding to its physiological ligand.	tmpzr1t_l9r_go_relaxed.owl	regulation of growth hormone receptor signalling pathway													biological_process											owl:Class	
GO:0046925	biolink:NamedThing	peptide cross-linking via 2-(S-L-cysteinyl)-D-phenylalanine	The cross-linking of a cysteine residue to an L-phenylalanine residue to form 2-(S-L-cysteinyl)-D-phenylalanine.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0341									biological_process											owl:Class	
GO:0110129	biolink:NamedThing	SHREC2 complex	A histone deacetylase complex formed by the association of an HP1 protein with a SHREC complex. The SHREC2 complex is required for deacetylation of H3K14, and mediates transcriptional gene silencing by limiting RNA polymerase II access to heterochromatin. In fission yeast, the complex contains the SHREC subunits Clr1, Clr2, Clr3, and Mit1, and the HP1 protein Chp2.	tmpzr1t_l9r_go_relaxed.owl								kmv	2018-09-25T21:25:41Z					cellular_component											owl:Class	
GO:0050764	biolink:NamedThing	regulation of phagocytosis	Any process that modulates the frequency, rate or extent of phagocytosis, the process in which phagocytes engulf external particulate material.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0033963	biolink:NamedThing	cholesterol-5,6-oxide hydrolase activity	Catalysis of the reactions: 5,6alpha-epoxy-5alpha-cholestan-3beta-ol + H2O = cholestane-3beta-5alpha,6beta-triol, and 5,6beta-epoxy-5beta-cholestan-3beta-ol + H2O = cholestane-3beta-5alpha,6beta-triol.	tmpzr1t_l9r_go_relaxed.owl	ChEH|cholesterol-epoxide hydrolase activity|5,6alpha-epoxy-5alpha-cholestan-3beta-ol hydrolase activity				MetaCyc:RXN-8650|EC:3.3.2.11|MetaCyc:RXN-8651									molecular_function											owl:Class	
GO:0140061	biolink:NamedThing	5-hydroxymethylcytosine dioxygenase activity	Catalysis of the reaction: 5-hydroxymethylcytosine + 2-oxoglutarate + O2 = 5-formylcytosine + succinate + CO2.	tmpzr1t_l9r_go_relaxed.owl	5hmC dioxygenase							pg	2017-07-20T09:54:50Z					molecular_function											owl:Class	
GO:0051470	biolink:NamedThing	ectoine transport	The directed movement of ectoine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidinecarboxylic acid) is a tetrahydropyrimidine commonly synthesized by halophilic bacteria.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0102550	biolink:NamedThing	2-methyl-6-geranylgeranyl-1,4-benzoquinol methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine  + 2-methyl-6-geranylgeranyl-1,4-benzoquinol <=> S-adenosyl-L-homocysteine  + 2,3-dimethyl-6-geranylgeranyl-1,4-benzoquinol + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-14917|EC:2.1.1.295|RHEA:38007									molecular_function											owl:Class	
GO:0045712	biolink:NamedThing	positive regulation of larval salivary gland boundary specification	Any process that activates or increases the frequency, rate or extent of salivary gland determination in a larval organism.	tmpzr1t_l9r_go_relaxed.owl	stimulation of larval salivary gland determination|positive regulation of larval salivary gland determination|activation of larval salivary gland determination|upregulation of larval salivary gland determination|up regulation of larval salivary gland determination|up-regulation of larval salivary gland determination													biological_process											owl:Class	
GO:0048313	biolink:NamedThing	Golgi inheritance	The partitioning of Golgi apparatus between daughter cells at cell division.	tmpzr1t_l9r_go_relaxed.owl	Golgi partitioning|Golgi division													biological_process											owl:Class	
GO:1904015	biolink:NamedThing	cellular response to serotonin	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a serotonin stimulus.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-03-06T19:34:00Z					biological_process											owl:Class	
GO:0071868	biolink:NamedThing	cellular response to monoamine stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monoamine stimulus. A monoamine is any of a group of molecular messengers that contain one amino group that is connected to an aromatic ring by ethylene group (-CH2-CH2-). Monoamines are derived from the aromatic amino acids phenylalanine, tyrosine, histidine and tryptophan.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-09-13T02:38:52Z					biological_process											owl:Class	
GO:0004315	biolink:NamedThing	3-oxoacyl-[acyl-carrier-protein] synthase activity	Catalysis of the reaction: acyl-[acyl-carrier protein] + malonyl-[acyl-carrier protein] = 3-oxoacyl-[acyl-carrier protein] + CO2 + [acyl-carrier protein].	tmpzr1t_l9r_go_relaxed.owl	3-oxoacyl-[acyl-carrier protein] synthase activity|KAS I activity|acyl-malonyl acyl carrier protein-condensing enzyme activity|beta-ketoacyl-acyl-carrier-protein synthase II activity|KAS II|acyl-acyl-carrier-protein:malonyl-acyl-carrier-protein C-acyltransferase (decarboxylating)|beta-ketoacyl-[acyl carrier protein] synthase activity|beta-ketoacylsynthase activity|beta-ketoacyl-ACP synthase I activity|beta-ketoacyl synthetase activity|KASII|3-oxoacyl-acyl-carrier-protein synthase activity|fatty acid condensing enzyme activity|3-ketoacyl-acyl carrier protein synthase activity|beta-ketoacyl-acyl carrier protein synthetase activity|condensing enzyme activity|beta-ketoacyl-ACP synthetase activity|3-oxoacyl-acyl carrier protein synthase I activity|acyl-malonyl(acyl-carrier-protein)-condensing enzyme activity|KASI|ketoacyl-ACP synthase activity|beta-ketoacyl acyl carrier protein synthase activity|beta-ketoacyl-ACP synthase II activity|beta-ketoacyl-acyl-carrier-protein synthase I|3-oxoacyl-ACP synthase activity|3-oxoacyl:ACP synthase I|beta-ketoacyl-acyl carrier protein synthase activity	https://github.com/geneontology/go-ontology/issues/21801			RHEA:22836|EC:2.3.1.41|MetaCyc:3-OXOACYL-ACP-SYNTH-RXN|MetaCyc:2.3.1.179-RXN							GO:0033817		molecular_function											owl:Class	
GO:0071161	biolink:NamedThing	cyanophycin synthetase activity (L-arginine-adding)	Catalysis of the reaction: ATP + [L-Asp(4-L-Arg)]n-L-Asp + L-arginine = ADP + phosphate + [L-Asp(4-L-Arg)]n+1.	tmpzr1t_l9r_go_relaxed.owl					EC:6.3.2.30|RHEA:23888			mah	2009-11-17T05:19:54Z					molecular_function											owl:Class	
GO:0061381	biolink:NamedThing	cell migration in diencephalon	The orderly movement of a cell that will reside in the diencephalon.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-11-09T09:54:27Z					biological_process											owl:Class	
GO:0021885	biolink:NamedThing	forebrain cell migration	The orderly movement of a cell from one site to another at least one of which is located in the forebrain.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0030797	biolink:NamedThing	24-methylenesterol C-methyltransferase activity	Catalysis of the reaction: 24-methylidenelophenol + S-adenosyl-L-methionine(1+) = (Z)-24-ethylidenelophenol + S-adenosyl-L-homocysteine + H(+).	tmpzr1t_l9r_go_relaxed.owl	S-adenosyl-L-methionine:24-methylenelophenol C-methyltransferase activity|24-methylenelophenol C-241-methyltransferase activity|SMT(2) activity|SMT2|24-methylenelophenol C-24(1)-methyltransferase activity				RHEA:21044|KEGG_REACTION:R05776|MetaCyc:2.1.1.143-RXN|EC:2.1.1.143									molecular_function											owl:Class	
GO:0048401	biolink:NamedThing	negative regulation of intermediate mesodermal cell fate specification	Any process that stops, prevents, or reduces the frequency, rate or extent of intermediate mesoderm cell fate specification.	tmpzr1t_l9r_go_relaxed.owl	downregulation of intermediate mesodermal cell fate specification|down regulation of intermediate mesodermal cell fate specification|inhibition of intermediate mesodermal cell fate specification|down-regulation of intermediate mesodermal cell fate specification													biological_process											owl:Class	
GO:0033346	biolink:NamedThing	asparagine catabolic process via 2-oxosuccinamate	The chemical reactions and pathways resulting in the breakdown of glutamate, via the intermediate 2-oxosuccinamate.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:PWY-4002									biological_process											owl:Class	
GO:0035843	biolink:NamedThing	endonuclear canal	A membrane-bound structure present in the nucleus of a spermatozoon. There is variation in the number of endonuclear canals between sperm of different organisms, and some species lack these structures altogether. The endonuclear canal may provide a supporting role for the sperm nucleus, and originates during spermiogenesis from an invagination of the nuclear envelope.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-05-06T01:45:03Z					cellular_component											owl:Class	
GO:0043814	biolink:NamedThing	phospholactate guanylyltransferase activity	Catalysis of the reaction: 2-phospho-(S)-lactate + GTP = lactyl-2-diphospho-5'-guanosine + diphosphate.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-8077|EC:2.7.7.68|RHEA:30519									molecular_function											owl:Class	
GO:2001116	biolink:NamedThing	methanopterin-containing compound biosynthetic process	The chemical reactions and pathways resulting in the formation of a methanopterin.	tmpzr1t_l9r_go_relaxed.owl	methanopterin biosynthesis							jl	2011-10-11T11:55:00Z					biological_process											owl:Class	
GO:0004609	biolink:NamedThing	phosphatidylserine decarboxylase activity	Catalysis of the reaction: H(+) + phosphatidyl-L-serine = CO(2) + phosphatidylethanolamine.	tmpzr1t_l9r_go_relaxed.owl	phosphatidyl-L-serine carboxy-lyase activity|phosphatidyl-L-serine carboxy-lyase (phosphatidylethanolamine-forming)|PS decarboxylase activity				RHEA:20828|Reactome:R-HSA-1483212|MetaCyc:PHOSPHASERDECARB-RXN|KEGG_REACTION:R02055|EC:4.1.1.65									molecular_function											owl:Class	
GO:0009911	biolink:NamedThing	positive regulation of flower development	Any process that activates or increases the frequency, rate or extent of flower development.	tmpzr1t_l9r_go_relaxed.owl	activation of flower development|up-regulation of flower development|up regulation of flower development|upregulation of flower development|stimulation of flower development													biological_process											owl:Class	
GO:1902055	biolink:NamedThing	positive regulation of neosartoricin biosynthetic process	Any process that activates or increases the frequency, rate or extent of neosartoricin biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	activation of neosartoricin synthesis|activation of neosartoricin biosynthetic process|positive regulation of neosartoricin synthesis|up regulation of neosartoricin formation|upregulation of neosartoricin biosynthesis|positive regulation of neosartoricin formation|activation of neosartoricin anabolism|up-regulation of neosartoricin anabolism|up-regulation of neosartoricin formation|up regulation of neosartoricin biosynthesis|up regulation of neosartoricin synthesis|up regulation of neosartoricin anabolism|upregulation of neosartoricin biosynthetic process|upregulation of neosartoricin formation|activation of neosartoricin formation|up-regulation of neosartoricin biosynthetic process|up-regulation of neosartoricin synthesis|positive regulation of neosartoricin anabolism|upregulation of neosartoricin anabolism|activation of neosartoricin biosynthesis|up-regulation of neosartoricin biosynthesis|positive regulation of neosartoricin biosynthesis|upregulation of neosartoricin synthesis|up regulation of neosartoricin biosynthetic process							di	2013-04-11T15:46:20Z					biological_process											owl:Class	
GO:0002513	biolink:NamedThing	tolerance induction to self antigen	Tolerance induction directed at self antigens.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0000802	biolink:NamedThing	transverse filament	A structural unit of the synaptonemal complex that spans the regions between the lateral elements and connects them.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:1990385	biolink:NamedThing	meiotic spindle midzone	The area in the center of the meiotic spindle where the spindle microtubules from opposite poles overlap.	tmpzr1t_l9r_go_relaxed.owl								kmv	2014-05-29T20:52:44Z					cellular_component											owl:Class	
GO:0006119	biolink:NamedThing	oxidative phosphorylation	The phosphorylation of ADP to ATP that accompanies the oxidation of a metabolite through the operation of the respiratory chain. Oxidation of compounds establishes a proton gradient across the membrane, providing the energy for ATP synthesis.	tmpzr1t_l9r_go_relaxed.owl	respiratory-chain phosphorylation				Wikipedia:Oxidative_phosphorylation									biological_process											owl:Class	
GO:0098632	biolink:NamedThing	cell-cell adhesion mediator activity	The binding by a cell-adhesion protein on the cell surface to an extracellular matrix component, to mediate adhesion of the cell to another cell.	tmpzr1t_l9r_go_relaxed.owl	cell-cell adhesion molecule|protein binding involved in cell-cell adhesion													molecular_function											owl:Class	
GO:0047097	biolink:NamedThing	phylloquinone monooxygenase (2,3-epoxidizing) activity	Catalysis of the reaction: AH(2) + O(2) + phylloquinone = 2,3-epoxyphylloquinone + A + H(2)O.	tmpzr1t_l9r_go_relaxed.owl	vitamin K 2,3-epoxidase activity|vitamin K epoxidase activity|vitamin K1 epoxidase activity|phylloquinone epoxidase activity|phylloquinone,hydrogen-donor:oxygen oxidoreductase (2,3-epoxidizing)				KEGG_REACTION:R03510|RHEA:16745|MetaCyc:1.14.99.20-RXN|EC:1.14.99.20									molecular_function											owl:Class	
GO:1904676	biolink:NamedThing	negative regulation of somatic stem cell division	Any process that stops, prevents or reduces the frequency, rate or extent of somatic stem cell division.	tmpzr1t_l9r_go_relaxed.owl	inhibition of somatic stem cell renewal|down regulation of somatic stem cell renewal|down-regulation of somatic stem cell division|down regulation of somatic stem cell division|inhibition of somatic stem cell division|downregulation of somatic stem cell division|downregulation of somatic stem cell renewal|down-regulation of somatic stem cell renewal|negative regulation of somatic stem cell renewal							rph	2015-09-14T08:47:28Z					biological_process											owl:Class	
GO:2000635	biolink:NamedThing	negative regulation of primary miRNA processing	Any process that stops, prevents or reduces the frequency, rate or extent of primary microRNA processing.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of pri-miRNA processing|negative regulation of primary microRNA processing							dph	2011-04-18T03:50:53Z					biological_process											owl:Class	
GO:0102973	biolink:NamedThing	norsolorinate anthrone synthase activity	Catalysis of the reaction: 7 malonyl-CoA + 5 H+ + a hexanoyl-[acyl-carrier-protein] = norsolorinate anthrone + 7 coenzyme A + 7 carbon dioxide + 2 H2O + a holo-[acyl-carrier protein].	tmpzr1t_l9r_go_relaxed.owl	norsolorinic acid synthase				RHEA:35179|EC:2.3.1.221|MetaCyc:RXN-9479									molecular_function											owl:Class	
GO:0008783	biolink:NamedThing	agmatinase activity	Catalysis of the reaction: agmatine + H(2)O = putrescine + urea.	tmpzr1t_l9r_go_relaxed.owl	agmatine amidinohydrolase|SpeB|agmatine ureohydrolase activity				Reactome:R-HSA-350604|KEGG_REACTION:R01157|MetaCyc:AGMATIN-RXN|RHEA:13929|EC:3.5.3.11									molecular_function											owl:Class	
GO:0004368	biolink:NamedThing	glycerol-3-phosphate dehydrogenase (quinone) activity	Catalysis of the reaction: sn-glycerol 3-phosphate + a quinone = glycerone phosphate + a quinol.	tmpzr1t_l9r_go_relaxed.owl	flavin-linked glycerol-3-phosphate dehydrogenase|FAD-dependent glycerol-3-phosphate dehydrogenase|sn-glycerol-3-phosphate dehydrogenase activity|L-glycerophosphate dehydrogenase activity|glycerol-3-phosphate CoQ reductase|sn-glycerol-3-phosphate:quinone oxidoreductase activity|glycerophosphate dehydrogenase activity				MetaCyc:RXN-9927|EC:1.1.5.3|RHEA:18977|MetaCyc:RXN0-5260|Reactome:R-HSA-188467	Note that enzymes classified as EC:1.1.5.3 have several activities. They should be annotated with the terms GO:0004368, GO:0052590 and GO:0052591.								molecular_function											owl:Class	
GO:0150158	biolink:NamedThing	positive regulation of interleukin-34 production	Any process that activates or increases the frequency, rate or extent of interleukin-34 production.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of interleukin-34 biosynthetic process							bc	2020-01-06T16:31:00Z			GO:0150161		biological_process											owl:Class	
GO:1905154	biolink:NamedThing	negative regulation of membrane invagination	Any process that stops, prevents or reduces the frequency, rate or extent of membrane invagination.	tmpzr1t_l9r_go_relaxed.owl	inhibition of membrane invagination|downregulation of membrane invagination|down-regulation of membrane invagination|down regulation of membrane invagination							bf	2016-04-18T15:44:04Z					biological_process											owl:Class	
GO:0048325	biolink:NamedThing	negative regulation of axial mesodermal cell fate determination	Any process that stops, prevents, or reduces the frequency, rate or extent of axial mesoderm cell fate determination.	tmpzr1t_l9r_go_relaxed.owl	downregulation of axial mesodermal cell fate determination|down regulation of axial mesodermal cell fate determination|down-regulation of axial mesodermal cell fate determination|inhibition of axial mesodermal cell fate determination													biological_process											owl:Class	
GO:0048324	biolink:NamedThing	regulation of axial mesodermal cell fate determination	Any process that modulates the frequency, rate or extent of axial mesoderm cell fate determination.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0010902	biolink:NamedThing	positive regulation of very-low-density lipoprotein particle remodeling	Any process that increases the rate, frequency or extent of very-low-density lipoprotein particle remodeling. Very-low-density lipoprotein particle remodeling is the acquisition, loss or modification of a protein or lipid within a very-low-density lipoprotein particle, including the hydrolysis of triglyceride by hepatic lipase or lipoprotein lipase and the subsequent loss of free fatty acid.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of VLDL remodeling													biological_process											owl:Class	
GO:0016679	biolink:NamedThing	oxidoreductase activity, acting on diphenols and related substances as donors	Catalysis of an oxidation-reduction (redox) reaction in which a diphenol or related substance acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.	tmpzr1t_l9r_go_relaxed.owl	oxidoreductase activity, acting on diphenols and related substances as donors, other acceptors				EC:1.10.-.-									molecular_function											owl:Class	
GO:0102302	biolink:NamedThing	mycinamicin VI 2''-O-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine  + mycinamicin VI <=> S-adenosyl-L-homocysteine  + mycinamicin III(1+) + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-12801|RHEA:31643|EC:2.1.1.238									molecular_function											owl:Class	
GO:1904149	biolink:NamedThing	regulation of microglial cell mediated cytotoxicity	Any process that modulates the frequency, rate or extent of microglial cell mediated cytotoxicity.	tmpzr1t_l9r_go_relaxed.owl								nc	2015-04-15T08:05:29Z					biological_process											owl:Class	
GO:0018574	biolink:NamedThing	2,6-dichloro-p-hydroquinone 1,2-dioxygenase activity	Catalysis of the reaction: 2,6-dichlorohydroquinone + O2 + H2O = HCl + 2 H+ + 2-chloromaleylacetate.	tmpzr1t_l9r_go_relaxed.owl					EC:1.13.11.-|UM-BBD_enzymeID:e0422									molecular_function											owl:Class	
GO:0007415	biolink:NamedThing	defasciculation of motor neuron axon	Separation of a motor axon away from a bundle of axons known as a fascicle.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0007414	biolink:NamedThing	axonal defasciculation	Separation of axons away from a bundle of axons known as a fascicle.	tmpzr1t_l9r_go_relaxed.owl	defasciculation of neuron													biological_process											owl:Class	
GO:1905363	biolink:NamedThing	positive regulation of endosomal vesicle fusion	Any process that activates or increases the frequency, rate or extent of endosomal vesicle fusion.	tmpzr1t_l9r_go_relaxed.owl	up regulation of endosome vesicle fusion|positive regulation of endosome vesicle fusion|upregulation of endosome vesicle fusion|up-regulation of endosome vesicle fusion|up regulation of endosomal vesicle fusion|activation of endosomal vesicle fusion|activation of endosome vesicle fusion|up-regulation of endosomal vesicle fusion|upregulation of endosomal vesicle fusion							bc	2016-08-16T11:40:51Z					biological_process											owl:Class	
GO:0055047	biolink:NamedThing	generative cell mitosis	The process in which the generative cell divides by mitosis to form two haploid cells. These will subsequently differentiate into sperm cells.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0097307	biolink:NamedThing	response to farnesol	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a farnesol stimulus.	tmpzr1t_l9r_go_relaxed.owl								pr	2012-05-15T03:51:31Z					biological_process											owl:Class	
GO:0072541	biolink:NamedThing	peroxynitrite reductase activity	Catalysis of the reaction: 2 R-SH + ONOO- = R-SS-R + NO2- + H2O.	tmpzr1t_l9r_go_relaxed.owl	peroxynitritase activity					Note that this activity is usually associated in vivo with an NADPH-dependent disulfide reductase activity, so that catalysis of the reduction of peroxynitrite to nitrite involves the possible creation of oxygen or water, using NADPH as reduction equivalent.		mah	2011-01-17T11:43:37Z					molecular_function											owl:Class	
GO:0097309	biolink:NamedThing	cap1 mRNA methylation	Methylation of the ribose of the first nucleotide of a 5'-capped mRNA.	tmpzr1t_l9r_go_relaxed.owl	cap1 mRNA capping							pr	2012-05-23T04:03:13Z					biological_process											owl:Class	
GO:0036451	biolink:NamedThing	cap mRNA methylation	Methylation of the 2'-O-ribose of the first or second transcribed nucleotide of a 5'-capped mRNA.	tmpzr1t_l9r_go_relaxed.owl								bf	2013-11-06T14:36:00Z					biological_process											owl:Class	
GO:0046372	biolink:NamedThing	D-arabinose metabolic process	The chemical reactions and pathways involving D-arabinose, the D-enantiomer of arabino-pentose. D-arabinose occurs in plant glycosides and is a constituent of arabinonucleosides.	tmpzr1t_l9r_go_relaxed.owl	D-arabinose metabolism													biological_process											owl:Class	
GO:0046360	biolink:NamedThing	2-oxobutyrate biosynthetic process	The chemical reactions and pathways resulting in the formation of 2-oxobutyrate, the anion of the organic acid 2-oxobutyric acid, which contains a ketone group on carbon 2.	tmpzr1t_l9r_go_relaxed.owl	2-oxobutyrate synthesis|alpha-ketobutyrate biosynthesis|2-oxobutyrate anabolism|2-oxobutyrate formation|2-oxobutyrate biosynthesis|alpha-ketobutyrate biosynthetic process													biological_process											owl:Class	
GO:0046361	biolink:NamedThing	2-oxobutyrate metabolic process	The chemical reactions and pathways involving 2-oxobutyrate, the anion of the organic acid 2-oxobutyric acid, which contains a ketone group on carbon 2.	tmpzr1t_l9r_go_relaxed.owl	alpha-ketobutyrate metabolism|alpha-ketobutyrate metabolic process|2-oxobutyrate metabolism													biological_process											owl:Class	
GO:0050390	biolink:NamedThing	valine decarboxylase activity	Catalysis of the reaction: L-valine + H(+) = 2-methylpropanamine + CO(2).	tmpzr1t_l9r_go_relaxed.owl	leucine decarboxylase activity|L-valine carboxy-lyase (2-methylpropanamine-forming)|L-valine carboxy-lyase activity				EC:4.1.1.14|KEGG_REACTION:R01437|MetaCyc:VALINE-DECARBOXYLASE-RXN|RHEA:18989|UM-BBD_reactionID:r1052									molecular_function											owl:Class	
GO:0043568	biolink:NamedThing	positive regulation of insulin-like growth factor receptor signaling pathway	Any process that increases the frequency, rate or extent of insulin-like growth factor receptor signaling.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of IGF receptor signaling pathway|stimulation of insulin-like growth factor receptor signaling pathway|up regulation of insulin-like growth factor receptor signaling pathway|upregulation of insulin-like growth factor receptor signaling pathway|up-regulation of insulin-like growth factor receptor signaling pathway|positive regulation of IGF receptor signalling pathway|positive regulation of insulin-like growth factor receptor signalling pathway|activation of insulin-like growth factor receptor signaling pathway													biological_process											owl:Class	
GO:0097696	biolink:NamedThing	receptor signaling pathway via STAT	An intracellular signal transduction process in which STAT proteins (Signal Transducers and Activators of Transcription) convey a signal to trigger a change in the activity or state of a cell. The STAT cascade begins with receptor activation followed by activation of STAT proteins by kinases. It proceeds through STA dimerization and subsequent nuclear translocation of STAT proteins, and ends with regulation of target gene expression by STAT proteins.	tmpzr1t_l9r_go_relaxed.owl	kinase activated-STAT cascade|STAT signalling pathway|kinase-STAT cascade					In most species, STAT proteins are activated by members of the JAK (Janus Activated Kinase) family of tyrosine kinases; the term GO:0007259 'JAK-STAT cascade' describes this specificity. In other cases, such as D. discoideum, no JAK orthologs are known, and STAT proteins are activated by tyrosine kinase-like proteins.		pr	2015-12-22T10:40:14Z					biological_process											owl:Class	
GO:0008475	biolink:NamedThing	procollagen-lysine 5-dioxygenase activity	Catalysis of the reaction: procollagen L-lysine + 2-oxoglutarate + O2 = procollagen 5-hydroxy-L-lysine + succinate + CO2.	tmpzr1t_l9r_go_relaxed.owl	procollagen-lysine,2-oxoglutarate 5-dioxygenase activity|lysine,2-oxoglutarate 5-dioxygenase activity|collagen lysine hydroxylase activity|protocollagen lysine hydroxylase activity|protocollagen lysine dioxygenase activity|lysine-2-oxoglutarate dioxygenase activity|lysylprotocollagen dioxygenase activity|lysine hydroxylase activity|procollagen-L-lysine,2-oxoglutarate:oxygen oxidoreductase (5-hydroxylating)|protocollagen lysyl hydroxylase activity|lysyl hydroxylase activity				EC:1.14.11.4|Reactome:R-HSA-1981104|MetaCyc:PROCOLLAGEN-LYSINE-5-DIOXYGENASE-RXN|RHEA:16569									molecular_function											owl:Class	
GO:0070815	biolink:NamedThing	peptidyl-lysine 5-dioxygenase activity	Catalysis of the reaction: protein L-lysine + 2-oxoglutarate + O2 = protein 5-hydroxy-L-lysine + succinate + CO2.	tmpzr1t_l9r_go_relaxed.owl	peptidyl-lysine, 2-oxoglutarate: oxygen oxidoreductase activity|lysyl hydroxylase activity|peptidyllysine, 2-oxoglutarate:oxygen 5-oxidoreductase activity|lysine,2-oxoglutarate 5-dioxygenase activity|lysine-2-oxoglutarate dioxygenase activity|lysine hydroxylase activity|protein lysine hydroxylase activity|peptide-lysine 5-dioxygenase activity							mah	2009-07-09T11:42:07Z					molecular_function											owl:Class	
GO:0004727	biolink:NamedThing	prenylated protein tyrosine phosphatase activity	Catalysis of the reaction: prenylated-protein tyrosine phosphate + H2O = prenylated-protein tyrosine + phosphate.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:2001075	biolink:NamedThing	negative regulation of metanephric ureteric bud development	Any process that stops, prevents or reduces the frequency, rate or extent of metanephric ureteric bud development.	tmpzr1t_l9r_go_relaxed.owl								yaf	2011-09-14T01:11:12Z					biological_process											owl:Class	
GO:0034393	biolink:NamedThing	positive regulation of smooth muscle cell apoptotic process	Any process that activates or increases the frequency, rate, or extent of smooth muscle cell apoptotic process.	tmpzr1t_l9r_go_relaxed.owl	stimulation of smooth muscle cell apoptosis|up-regulation of smooth muscle cell apoptosis|positive regulation of smooth muscle cell apoptosis|upregulation of smooth muscle cell apoptosis|positive regulation of SMC apoptosis|up regulation of smooth muscle cell apoptosis|activation of smooth muscle cell apoptosis													biological_process											owl:Class	
GO:2001040	biolink:NamedThing	positive regulation of cellular response to drug	Any process that activates or increases the frequency, rate or extent of cellular response to drug.	tmpzr1t_l9r_go_relaxed.owl								yaf	2011-08-27T04:12:25Z					biological_process											owl:Class	
GO:0050825	biolink:NamedThing	ice binding	Binding to ice, water reduced to the solid state by cold temperature. It is a white or transparent colorless substance, crystalline, brittle, and viscoidal.	tmpzr1t_l9r_go_relaxed.owl	antifreeze activity|ice crystal binding|ice nucleation activity|ice nucleation inhibitor activity													molecular_function											owl:Class	
GO:0060269	biolink:NamedThing	centripetally migrating follicle cell migration	The cell migration process in which a follicle cell migrates as part of an epithelial sheet between the nurse cells and the oocyte. At the end of migration, they cover the anterior of the oocyte.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0150006	biolink:NamedThing	urease activator complex	A protein complex required for the activation of urease. Activator subunits dissociate before urease has catalytic function.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0150005	biolink:NamedThing	enzyme activator complex	A protein complex capable of activating an enzyme. Activating subunits may dissociate from the catalytic unit before the enzyme is active.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:1902007	biolink:NamedThing	regulation of toxin transport	Any process that modulates the frequency, rate or extent of toxin transport.	tmpzr1t_l9r_go_relaxed.owl								dph	2013-03-22T12:53:56Z					biological_process											owl:Class	
GO:0043454	biolink:NamedThing	alkyne catabolic process	The chemical reactions and pathways resulting in the breakdown of an alkyne, any acyclic branched or unbranched hydrocarbon (compound composed only of carbon and hydrogen) having a carbon-carbon triple bond and the general formula CnH2n-2.	tmpzr1t_l9r_go_relaxed.owl	alkyne catabolism|alkyne degradation|alkyne breakdown													biological_process											owl:Class	
GO:0051408	biolink:NamedThing	glyceraldehyde 3-phosphate:inorganic phosphate antiporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glyceraldehyde 3-phosphate(out) + phosphate(in) = glyceraldehyde 3-phosphate(in) + phosphate(out).	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0061000	biolink:NamedThing	negative regulation of dendritic spine development	Any process that decreases the rate, frequency, or extent of dendritic spine development, the process whose specific outcome is the progression of the dendritic spine over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-01-20T09:29:18Z					biological_process											owl:Class	
GO:0030029	biolink:NamedThing	actin filament-based process	Any cellular process that depends upon or alters the actin cytoskeleton, that part of the cytoskeleton comprising actin filaments and their associated proteins.	tmpzr1t_l9r_go_relaxed.owl	microfilament-based process													biological_process											owl:Class	
GO:1905959	biolink:NamedThing	positive regulation of cellular response to alcohol	Any process that activates or increases the frequency, rate or extent of cellular response to alcohol.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of cellular response to alcohol|upregulation of cellular response to alcohol|activation of cellular response to alcohol|up regulation of cellular response to alcohol							hbye	2017-02-22T12:03:16Z					biological_process											owl:Class	
GO:0072351	biolink:NamedThing	tricarboxylic acid biosynthetic process	The chemical reactions and pathways resulting in the formation of dicarboxylic acids, any organic acid containing three carboxyl (-COOH) groups.	tmpzr1t_l9r_go_relaxed.owl	tricarboxylic acid biosynthesis|tricarboxylate biosynthesis|tricarboxylic acid formation|tricarboxylic acid anabolism|tricarboxylate biosynthetic process|tricarboxylic acid synthesis							mah	2010-11-11T05:08:54Z					biological_process											owl:Class	
GO:0005372	biolink:NamedThing	water transmembrane transporter activity	Enables the transfer of water (H2O) from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0000256	biolink:NamedThing	allantoin catabolic process	The chemical reactions and pathways resulting in the breakdown of allantoin, (2,5-dioxo-4-imidazolidinyl)urea.	tmpzr1t_l9r_go_relaxed.owl	allantoin catabolism|allantoin breakdown|allantoin degradation													biological_process											owl:Class	
GO:0071281	biolink:NamedThing	cellular response to iron ion	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iron ion stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to iron							mah	2009-12-10T03:57:22Z					biological_process											owl:Class	
GO:0010039	biolink:NamedThing	response to iron ion	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iron ion stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to iron													biological_process											owl:Class	
GO:0018758	biolink:NamedThing	2,4-dihydroxy-6-(N'-ethyl)amino-1,3,5-triazine aminohydrolase activity	Catalysis of the reaction: 2,4-dihydroxy-6-(N'-ethyl)amino-1,3,5-triazine + H2O = CH3CH2NH2 + cyanuric acid.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0122									molecular_function											owl:Class	
GO:0046957	biolink:NamedThing	negative phototaxis	The directed movement of a cell or organism away from a source of light.	tmpzr1t_l9r_go_relaxed.owl	negative phototactic behavior|negative taxis in response to light|negative phototactic behaviour											GO:0046955		biological_process											owl:Class	
GO:0042331	biolink:NamedThing	phototaxis	The directed movement of a motile cell or organism in response to light.	tmpzr1t_l9r_go_relaxed.owl	taxis in response to light|phototactic behavior|phototactic behaviour				Wikipedia:Phototaxis							GO:0046953		biological_process											owl:Class	
GO:0009824	biolink:NamedThing	AMP dimethylallyltransferase activity	Catalysis of the reaction: AMP + dimethylallyl diphosphate = N(6)-(dimethylallyl)adenosine 5'-phosphate + diphosphate.	tmpzr1t_l9r_go_relaxed.owl	adenylate dimethylallyltransferase activity|cytokinin synthase activity|dimethylallyl-diphosphate:AMP dimethylallyltransferase activity|adenylate isopentenyltransferase activity|isopentenyltransferase activity|2-isopentenyl-diphosphate:AMP 2-isopentenyltransferase activity|2-isopentenyl-diphosphate:AMP delta2-isopentenyltransferase activity				EC:2.5.1.27|KEGG_REACTION:R04038|RHEA:15285|MetaCyc:RXN-4307									molecular_function											owl:Class	
GO:0050597	biolink:NamedThing	taxane 10-beta-hydroxylase activity	Catalysis of the reaction: H(+) + NADPH + O(2) + taxa-4(20),11-dien-5alpha-yl acetate = 10beta-hydroxytaxa-4(20),11-dien-5alpha-yl acetate + H(2)O + NADP(+).	tmpzr1t_l9r_go_relaxed.owl	5-alpha-taxadienol-10-beta-hydroxylase activity|taxane 10beta-hydroxylase activity|taxane 10b-hydroxylase activity|taxa-4(20),11-dien-5alpha-yl acetate,NADPH:oxygen oxidoreductase (10beta-hydroxylating)				RHEA:15241|MetaCyc:1.14.13.76-RXN|KEGG_REACTION:R06309|EC:1.14.14.105									molecular_function											owl:Class	
GO:1990626	biolink:NamedThing	mitochondrial outer membrane fusion	The membrane organization process that joins two mitochondrial outer membranes to form a single membrane.	tmpzr1t_l9r_go_relaxed.owl	mitochondrion outer membrane fusion							vw	2015-02-02T11:32:17Z					biological_process											owl:Class	
GO:0043875	biolink:NamedThing	2-ketobutyrate formate-lyase activity	Catalysis of the reaction: 2-oxobutanoate + coenzyme A = propionyl-CoA + formate.	tmpzr1t_l9r_go_relaxed.owl	KFL|TdcE|keto-acid formate acetyltransferase				MetaCyc:KETOBUTFORMLY-RXN	This function is part of an anaerobic pathway for the catabolism of L-threonine.								molecular_function											owl:Class	
GO:2000959	biolink:NamedThing	positive regulation of cyclodextrin catabolic process	Any process that activates or increases the frequency, rate or extent of cyclodextrin catabolic process.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of cyclodextrin catabolism							tt	2011-08-01T02:24:06Z					biological_process											owl:Class	
GO:2000956	biolink:NamedThing	positive regulation of cyclodextrin metabolic process	Any process that activates or increases the frequency, rate or extent of cyclodextrin metabolic process.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of cyclodextrin metabolism							tt	2011-08-01T02:22:09Z					biological_process											owl:Class	
GO:0086037	biolink:NamedThing	P-type sodium:potassium-exchanging transporter activity involved in regulation of cardiac muscle cell membrane potential	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Na+(in) + K+(out) = ADP + phosphate + Na+(out) + K+(in), that contributes to regulating the membrane potential of a cardiac muscle cell.	tmpzr1t_l9r_go_relaxed.owl								tb	2011-11-11T03:33:44Z					molecular_function											owl:Class	
GO:0005391	biolink:NamedThing	P-type sodium:potassium-exchanging transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Na+(in) + K+(out) = ADP + phosphate + Na+(out) + K+(in).	tmpzr1t_l9r_go_relaxed.owl	P-type sodium:potassium-exchanging ATPase activity|Na+,K+-ATPase activity|sodium/potassium-exchanging ATPase activity|sodium pump|Na(+)/K(+)-exchanging ATPase activity|Na+/K+-ATPase activity|Na+/K+-exchanging ATPase activity|Na(+)/K(+)-ATPase activity|sodium:potassium exchanging ATPase activity|sodium:potassium-exchanging ATPase activity|sodium/potassium-transporting ATPase activity|Na,K-activated ATPase activity	https://github.com/geneontology/go-ontology/issues/17289			Wikipedia:ATPase,_Na%2B/K%2B_transporting,_alpha_1|RHEA:18353|TC:3.A.3.1.1|EC:7.2.2.13|Reactome:R-HSA-936897|MetaCyc:3.6.3.9-RXN									molecular_function											owl:Class	
GO:0042961	biolink:NamedThing	ATPase-coupled antimonite transmembrane transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + antimonite(in) = ADP + phosphate + antimonite(out).	tmpzr1t_l9r_go_relaxed.owl	antimonite-transporting ATPase activity|ATP-dependent antimonite transporter activity													molecular_function											owl:Class	
GO:0103088	biolink:NamedThing	2-(6'-methylthio)hexylmalate synthase activity	Catalysis of the reaction: 2-oxo-8-methylthiooctanoate + acetyl-CoA + H2O <=> H+ + 2-(6'-methylthio)hexylmalate + coenzyme A.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXNQT-4172									molecular_function											owl:Class	
GO:0045917	biolink:NamedThing	positive regulation of complement activation	Any process that activates or increases the frequency, rate or extent of complement activation.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of complement activation|activation of complement activation|up regulation of complement activation|positive regulation of complement cascade|upregulation of complement activation|stimulation of complement activation													biological_process											owl:Class	
GO:0015317	biolink:NamedThing	phosphate:proton symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: phosphate(out) + H+(out) = phosphate(in) + H+(in).	tmpzr1t_l9r_go_relaxed.owl	phosphate:hydrogen symporter activity|phosphate ion carrier activity	https://github.com/geneontology/go-ontology/issues/14221										GO:0015320		molecular_function											owl:Class	
GO:0030780	biolink:NamedThing	12-hydroxydihydrochelirubine 12-O-methyltransferase activity	Catalysis of the reaction: 12-hydroxydihydrochelirubine + S-adenosyl-L-methionine(1+) = S-adenosyl-L-homocysteine + dihydromacarpine + H(+).	tmpzr1t_l9r_go_relaxed.owl	S-adenosyl-L-methionine:12-hydroxydihydrochelirubine 12-O-methyltransferase activity				KEGG_REACTION:R04705|EC:2.1.1.120|MetaCyc:2.1.1.120-RXN|RHEA:21092									molecular_function											owl:Class	
GO:0018398	biolink:NamedThing	peptidyl-phenylalanine bromination to L-3'-bromophenylalanine	The bromination of peptidyl-phenylalanine to form L-3'-bromophenylalanine.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0175									biological_process											owl:Class	
GO:0050887	biolink:NamedThing	determination of sensory modality	The determination of the type or quality of a sensation. Sensory modalities include touch, thermal sensation, visual sensation, auditory sensation and pain.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0046151	biolink:NamedThing	eye pigment catabolic process	The chemical reactions and pathways resulting in the breakdown of eye pigments, any general or particular coloring matter in living organisms, found or utilized in the eye.	tmpzr1t_l9r_go_relaxed.owl	eye pigment breakdown|eye pigment catabolism|eye pigment degradation													biological_process											owl:Class	
GO:0046413	biolink:NamedThing	organomercury catabolic process	The chemical reactions and pathways resulting in the breakdown of organomercury compounds, any organic compound containing a mercury atom.	tmpzr1t_l9r_go_relaxed.owl	organomercury breakdown|organomercury degradation|organomercury catabolism													biological_process											owl:Class	
GO:0047288	biolink:NamedThing	monosialoganglioside sialyltransferase activity	Catalysis of the reaction: D-galactosyl-N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide + CMP-N-acetylneuraminate = N-acetylneuraminyl-D-galactosyl-N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide + CMP.	tmpzr1t_l9r_go_relaxed.owl	CMP-N-acetylneuraminate:D-galactosyl-N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide N-acetylneuraminyltransferase activity				MetaCyc:2.4.99.2-RXN|RHEA:18021|EC:2.4.99.2									molecular_function											owl:Class	
GO:0008205	biolink:NamedThing	ecdysone metabolic process	The chemical reactions and pathways involving ecdysone, (22R)-2-beta,3-beta,14,22,25-pentahydroxycholest-7-en-6-one, an ecdysteroid found in insects. It is the inactive prohormone of the moulting hormone ecdysterone and may have intrinsic hormonal activity at other stages of insect development.	tmpzr1t_l9r_go_relaxed.owl	ecdysone metabolism													biological_process											owl:Class	
GO:2000036	biolink:NamedThing	regulation of stem cell population maintenance	Any process that modulates the frequency, rate or extent of stem cell population maintenance.	tmpzr1t_l9r_go_relaxed.owl	regulation of maintenance of pluripotency							tb	2010-08-05T11:35:25Z					biological_process											owl:Class	
GO:0052573	biolink:NamedThing	UDP-D-galactose metabolic process	The chemical reactions and pathways involving UDP-D-galactose, a substance composed of D-galactose in glycosidic linkage with guanosine diphosphate.	tmpzr1t_l9r_go_relaxed.owl	UDP-D-galactopyranose metabolic process|uridine diphosphate galactose metabolism|UDP-D-galactose metabolism|uridine diphosphate galactose metabolic process|UDP-galactose metabolic process|UDP-galactose metabolism|UDP-D-galactopyranose metabolism								2010-07-23T03:29:57Z					biological_process											owl:Class	
GO:1904261	biolink:NamedThing	positive regulation of basement membrane assembly involved in embryonic body morphogenesis	Any process that activates or increases the frequency, rate or extent of basement membrane assembly involved in embryonic body morphogenesis.	tmpzr1t_l9r_go_relaxed.owl	upregulation of basement membrane assembly involved in embryonic body morphogenesis|activation of basement membrane assembly involved in embryonic body morphogenesis|up-regulation of basement membrane assembly involved in embryonic body morphogenesis|up regulation of basement membrane assembly involved in embryonic body morphogenesis							als	2015-05-21T09:20:55Z					biological_process											owl:Class	
GO:0010592	biolink:NamedThing	positive regulation of lamellipodium assembly	Any process that increases the rate, frequency or extent of the formation of a lamellipodium, a thin sheetlike extension of the surface of a migrating cell.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of lamellipodium biogenesis													biological_process											owl:Class	
GO:0010591	biolink:NamedThing	regulation of lamellipodium assembly	Any process that modulates the rate, frequency or extent of the formation of a lamellipodium, a thin sheetlike extension of the surface of a migrating cell.	tmpzr1t_l9r_go_relaxed.owl	regulation of lamellipodium biogenesis													biological_process											owl:Class	
GO:0051122	biolink:NamedThing	hepoxilin biosynthetic process	The chemical reactions and pathways resulting in the formation of hepoxilins, a class of bioactive icosanoids with roles in the regulation of cell physiology.	tmpzr1t_l9r_go_relaxed.owl	hepoxilin formation|hepoxilin biosynthesis|hepoxilin anabolism|hepoxilin synthesis													biological_process											owl:Class	
GO:0051121	biolink:NamedThing	hepoxilin metabolic process	The chemical reactions and pathways involving hepoxilins, a class of bioactive icosanoids with roles in the regulation of cell physiology.	tmpzr1t_l9r_go_relaxed.owl	hepoxilin metabolism													biological_process											owl:Class	
GO:0140252	biolink:NamedThing	regulation protein catabolic process at postsynapse	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein at the postsynapse.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/synapse/issues/204				Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.		pg	2018-07-15T10:35:56Z					biological_process											owl:Class	
GO:0052863	biolink:NamedThing	1-deoxy-D-xylulose 5-phosphate metabolic process	The chemical reactions and pathways involving 1-deoxy-D-xylulose 5-phosphate, the 5-phospho derivative of 1-deoxy-D-xylulose. 1-deoxy-D-xylulose 5-phosphate is an intermediate in the non-mevalonate pathway and a common precursor for isoprenoid, thiamin, and pyridoxol biosynthesis.	tmpzr1t_l9r_go_relaxed.owl	(2R,3S)-2,3-dihydroxy-4-oxopentyl dihydrogen phosphate metabolism|1-deoxy-D-xylulose 5-phosphate metabolism|(2R,3S)-2,3-dihydroxy-4-oxopentyl dihydrogen phosphate metabolic process													biological_process											owl:Class	
GO:1902709	biolink:NamedThing	cellular response to plumbagin	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a plumbagin stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2014-02-20T13:50:04Z					biological_process											owl:Class	
GO:0014024	biolink:NamedThing	neural rod cavitation	The process of rod cavitation, which is the formation of a lumen in the neural rod during primary neurulation, producing the neural tube.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0018276	biolink:NamedThing	isopeptide cross-linking via N6-glycyl-L-lysine	The formation of an isopeptide cross-link between peptidyl-lysine and peptidyl-glycine to produce N6-glycyl-L-lysine. This is distinct from the formation of the thiolester intermediate, which occurs during ubiquitination.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0125	See also the biological process term 'peptide cross-linking via S-glycyl-L-cysteine ; GO:0018255'.								biological_process											owl:Class	
GO:0047680	biolink:NamedThing	aryl-acylamidase activity	Catalysis of the reaction: anilide + H(2)O = a carboxylate + aniline + H(+).	tmpzr1t_l9r_go_relaxed.owl	pseudocholinesterase (associated with arylacylamidase)|AAA-1|AAA-2|brain acetylcholinesterase (is associated with AAA-2)|aryl-acylamide amidohydrolase activity				RHEA:20297|EC:3.5.1.13|KEGG_REACTION:R01862|MetaCyc:ARYL-ACYLAMIDASE-RXN									molecular_function											owl:Class	
GO:0000913	biolink:NamedThing	preprophase band assembly	The aggregation, arrangement and bonding together of a set of components to form the preprophase band, a dense band of microtubules that marks the position in the cell where cytokinesis will occur in cells that perform cytokinesis by cell plate formation.	tmpzr1t_l9r_go_relaxed.owl	preprophase band formation													biological_process											owl:Class	
GO:1904340	biolink:NamedThing	positive regulation of dopaminergic neuron differentiation	Any process that activates or increases the frequency, rate or extent of dopaminergic neuron differentiation.	tmpzr1t_l9r_go_relaxed.owl	activation of dopaminergic neuron differentiation|up-regulation of dopaminergic neuron differentiation|up regulation of dopaminergic neuron differentiation|upregulation of dopaminergic neuron differentiation							sl	2015-06-11T18:06:32Z					biological_process											owl:Class	
GO:1904338	biolink:NamedThing	regulation of dopaminergic neuron differentiation	Any process that modulates the frequency, rate or extent of dopaminergic neuron differentiation.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-06-11T18:06:19Z					biological_process											owl:Class	
GO:1904137	biolink:NamedThing	negative regulation of convergent extension involved in notochord morphogenesis	Any process that stops, prevents or reduces the frequency, rate or extent of convergent extension involved in notochord morphogenesis.	tmpzr1t_l9r_go_relaxed.owl	downregulation of convergent extension involved in notochord morphogenesis|down-regulation of convergent extension involved in notochord morphogenesis|inhibition of convergent extension involved in notochord morphogenesis|down regulation of convergent extension involved in notochord morphogenesis							dph	2015-04-10T21:21:36Z					biological_process											owl:Class	
GO:0032784	biolink:NamedThing	regulation of DNA-templated transcription, elongation	Any process that modulates the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides catalyzed by a DNA-dependent RNA polymerase.	tmpzr1t_l9r_go_relaxed.owl	regulation of RNA elongation|regulation of DNA-dependent transcription, elongation|transcription elongation regulator activity|regulation of transcriptional elongation|regulation of transcription elongation, DNA-dependent													biological_process											owl:Class	
GO:0034412	biolink:NamedThing	ascospore wall beta-glucan biosynthetic process	The chemical reactions and pathways resulting in the formation of beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds, found in the walls of ascospores.	tmpzr1t_l9r_go_relaxed.owl	ascospore wall beta-glucan formation|ascospore wall beta-glucan anabolism|ascospore wall beta-glucan synthesis|ascospore wall beta-glucan biosynthesis													biological_process											owl:Class	
GO:0052729	biolink:NamedThing	dimethylglycine N-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + N,N-dimethylglycine = S-adenosyl-L-homocysteine + betaine.	tmpzr1t_l9r_go_relaxed.owl	ApDMT|S-adenosyl-L-methionine:N,N-dimethylglycine N-methyltransferase activity				EC:2.1.1.161|MetaCyc:RXN-9680|EC:2.1.1.162|EC:2.1.1.157|MetaCyc:R482-RXN|KEGG_REACTION:R07244|RHEA:10072			ai	2011-08-16T03:45:16Z					molecular_function											owl:Class	
GO:0035668	biolink:NamedThing	TRAM-dependent toll-like receptor signaling pathway	Any series of molecular signals generated as a consequence of binding to a toll-like receptor where the TRAM adaptor mediates transduction of the signal. Toll-like receptors directly bind pattern motifs from a variety of microbial sources to initiate innate immune response.	tmpzr1t_l9r_go_relaxed.owl	TRAM-dependent toll-like receptor signalling pathway|TRAM-dependent TLR signaling pathway							bf	2011-02-01T02:39:34Z					biological_process											owl:Class	
GO:0089705	biolink:NamedThing	protein localization to outer membrane	A process in which a protein is transported to, or maintained in, a specific location the cell outer membrane.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0043501	biolink:NamedThing	skeletal muscle adaptation	Any process in which skeletal muscles change their phenotypic profiles in response to altered functional demands and a variety of signals.	tmpzr1t_l9r_go_relaxed.owl	skeletal muscle plasticity													biological_process											owl:Class	
GO:0055045	biolink:NamedThing	antipodal cell degeneration	The process in which the antipodal cells undergo programmed cell death.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1900665	biolink:NamedThing	negative regulation of emodin biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of emodin biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	downregulation of emodin anabolism|downregulation of emodin formation|inhibition of emodin formation|down regulation of emodin synthesis|negative regulation of emodin biosynthesis|negative regulation of emodin anabolism|downregulation of emodin biosynthetic process|down-regulation of emodin formation|inhibition of emodin synthesis|negative regulation of emodin synthesis|inhibition of emodin anabolism|down regulation of emodin anabolism|inhibition of emodin biosynthesis|down-regulation of emodin anabolism|down regulation of emodin biosynthesis|down-regulation of emodin synthesis|down-regulation of emodin biosynthesis|inhibition of emodin biosynthetic process|negative regulation of emodin formation|downregulation of emodin synthesis|down-regulation of emodin biosynthetic process|down regulation of emodin biosynthetic process|down regulation of emodin formation|downregulation of emodin biosynthesis							di	2012-05-22T04:14:58Z					biological_process											owl:Class	
GO:1903280	biolink:NamedThing	negative regulation of calcium:sodium antiporter activity	Any process that stops, prevents or reduces the frequency, rate or extent of calcium:sodium antiporter activity.	tmpzr1t_l9r_go_relaxed.owl	downregulation of sodium:calcium exchange|downregulation of mitochondrial sodium/calcium ion exchange|down regulation of calcium:sodium antiporter activity|inhibition of sodium/calcium exchanger|inhibition of calcium:sodium antiporter activity|negative regulation of mitochondrial sodium/calcium ion exchange|down-regulation of sodium:calcium exchange|inhibition of sodium:calcium exchange|down-regulation of mitochondrial sodium/calcium ion exchange|downregulation of calcium:sodium antiporter activity|down regulation of sodium/calcium exchanger|negative regulation of sodium:calcium exchange|down regulation of mitochondrial sodium/calcium ion exchange|down-regulation of calcium:sodium antiporter activity|downregulation of sodium/calcium exchanger|inhibition of mitochondrial sodium/calcium ion exchange|down regulation of sodium:calcium exchange|negative regulation of sodium/calcium exchanger|down-regulation of sodium/calcium exchanger							rl	2014-08-11T12:53:38Z					biological_process											owl:Class	
GO:0000467	biolink:NamedThing	exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	Exonucleolytic digestion of a pre-rRNA molecule to generate the mature 3'-end of a 5.8S rRNA molecule derived from an originally tricistronic pre-rRNA transcript that contained the Small Subunit (SSU) rRNA, the 5.8S rRNA, and the Large Subunit (LSU) rRNA in that order from 5' to 3' along the primary transcript.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0010230	biolink:NamedThing	alternative respiration	Alternative respiration pathway consumes oxygen, oxidizes NADH to NAD+ and generates water. During electron flow, proton motive force is diminished resulting in fewer molecules of ATP compared to cytochrome pathway. The pathway is found in plants, algae and some protozoa.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0051612	biolink:NamedThing	negative regulation of serotonin uptake	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of serotonin into a cell.	tmpzr1t_l9r_go_relaxed.owl	downregulation of serotonin uptake|negative regulation of 5-HT uptake|down-regulation of serotonin uptake|negative regulation of 5-hydroxytryptamine uptake|negative regulation of 5HT uptake|negative regulation of serotonin import|down regulation of serotonin uptake													biological_process											owl:Class	
GO:0046094	biolink:NamedThing	deoxyinosine metabolic process	The chemical reactions and pathways involving deoxyinosine, hypoxanthine deoxyriboside.	tmpzr1t_l9r_go_relaxed.owl	deoxyinosine metabolism													biological_process											owl:Class	
GO:0016136	biolink:NamedThing	saponin catabolic process	The chemical reactions and pathways resulting in the breakdown of saponins, glycosides of plants in which the aglycan (sapogenin) group is a terpene or steroid and the sugar group is a glucose, a galactose, a pentose, a methylpentose or an oligosaccharide. Saponins are powerful surfactant agents and membrane active; they are, hence, toxic to animals on injection.	tmpzr1t_l9r_go_relaxed.owl	saponin breakdown|saponin catabolism|saponin degradation													biological_process											owl:Class	
GO:0016134	biolink:NamedThing	saponin metabolic process	The chemical reactions and pathways involving saponins, glycosides of plants in which the aglycan (sapogenin) group is a terpene or steroid and the sugar group is a glucose, a galactose, a pentose, a methylpentose or an oligosaccharide. Saponins are powerful surfactant agents and membrane active; they are, hence, toxic to animals on injection.	tmpzr1t_l9r_go_relaxed.owl	saponin metabolism													biological_process											owl:Class	
GO:0051616	biolink:NamedThing	regulation of histamine uptake	Any process that modulates the frequency, rate or extent of the directed movement of the neurotransmitter histamine into a cell.	tmpzr1t_l9r_go_relaxed.owl	regulation of histamine import													biological_process											owl:Class	
GO:0042757	biolink:NamedThing	giant axon	Extremely large, unmyelinated axon found in invertebrates. Has high conduction speeds and is usually involved in panic or escape responses.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0018959	biolink:NamedThing	aerobic phenol-containing compound metabolic process	The chemical reactions and pathways involving a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring, in the presence of oxygen.	tmpzr1t_l9r_go_relaxed.owl	aerobic phenol-containing compound metabolism				UM-BBD_pathwayID:pba									biological_process											owl:Class	
GO:0000921	biolink:NamedThing	septin ring assembly	The aggregation, arrangement and bonding together of septins and associated proteins to form an organized structure resembling a ring at the cell cortex.	tmpzr1t_l9r_go_relaxed.owl	septin assembly and septum biosynthesis|septin assembly and septum formation													biological_process											owl:Class	
GO:0031106	biolink:NamedThing	septin ring organization	Control of the formation, spatial distribution, and breakdown of the septin ring.	tmpzr1t_l9r_go_relaxed.owl	septin ring organisation													biological_process											owl:Class	
GO:0106243	biolink:NamedThing	syn-isopimara-7,15-diene synthase activity	Catalysis of the reaction: 9alpha-copalyl diphosphate = diphosphate + syn-isopimara-7,15-diene.	tmpzr1t_l9r_go_relaxed.owl					RHEA:62188			hjd	2019-12-19T19:04:32Z					molecular_function											owl:Class	
GO:0071311	biolink:NamedThing	cellular response to acetate	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acetate stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-12-10T04:48:16Z					biological_process											owl:Class	
GO:0034478	biolink:NamedThing	phosphatidylglycerol catabolic process	The chemical reactions and pathways resulting in the breakdown of phosphatidylglycerols, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of glycerol.	tmpzr1t_l9r_go_relaxed.owl	phosphatidylglycerol catabolism|phosphatidylglycerol degradation|phosphatidylglycerol breakdown													biological_process											owl:Class	
GO:1990612	biolink:NamedThing	Sad1-Kms1 LINC complex	A LINC complex implicated in the connection of DNA double strand breaks to the cytoskeleton during DNA double-strand break repair.	tmpzr1t_l9r_go_relaxed.owl								jl	2015-01-20T13:10:49Z					cellular_component											owl:Class	
GO:0034993	biolink:NamedThing	meiotic nuclear membrane microtubule tethering complex	A nuclear membrane  protein complex  which connects the nuclear outer and inner membranes together, and links links the nuclear lumen to cytoplasmic microtubules during meiosis.	tmpzr1t_l9r_go_relaxed.owl	SUN-KASH complex|LInker of Nucleoskeleton and Cytoskeleton complex|LINC complex													cellular_component											owl:Class	
GO:0052892	biolink:NamedThing	aromatic (S)-hydroxynitrile lyase activity	Catalysis of the reaction: an aromatic (S)-hydroxynitrile = an aromatic aldehyde + cyanide.	tmpzr1t_l9r_go_relaxed.owl	(S)-cyanohydrin carbonyl-lyase (cyanide forming) activity|(S)-oxynitrilase activity|(S)-selective hydroxynitrile lyase activity|hydroxynitrile lyase activity|(S)-cyanohydrin producing hydroxynitrile lyase activity|oxynitrilase activity|(S)-hydroxynitrile lyase activity				EC:4.1.2.47|KEGG_REACTION:R09359|RHEA:54660|MetaCyc:RXN-11732									molecular_function											owl:Class	
GO:0000424	biolink:NamedThing	micromitophagy	Degradation of a mitochondrion by lysosomal microautophagy.	tmpzr1t_l9r_go_relaxed.owl						Note that this term is not a child of mitophagy because the community genrally uses that latter to refer to the macroautophagy of mitochondria.								biological_process											owl:Class	
GO:0016237	biolink:NamedThing	lysosomal microautophagy	The transfer of cytosolic components into the lysosomal compartment by direct invagination of the lysosomal membrane without prior sequestration into an autophagosome. The engulfing membranes fuse, resulting in the lysosomal delivery of the cargo wrapped in a single membrane derived from the invaginated lysosomal membrane. In S. cerevisiae, the vacuole is the lysosomal compartment.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1903360	biolink:NamedThing	protein localization to lateral cortical node	A process in which a protein is transported to, or maintained in, a location within a lateral cortical node.	tmpzr1t_l9r_go_relaxed.owl	protein localization in lateral cortical node|protein localisation in lateral cortical node|protein localisation to lateral cortical node							mah	2014-08-21T10:23:00Z					biological_process											owl:Class	
GO:0001175	biolink:NamedThing	transcriptional start site selection at RNA polymerase III promoter	Any process involved in the selection of the specific location within the template strand of an RNA polymerase III promoter for hybridization of the cognate ribonucleotides and formation of first phosphodiester bond within the nascent transcript.	tmpzr1t_l9r_go_relaxed.owl								krc	2011-06-20T01:47:38Z					biological_process											owl:Class	
GO:0001173	biolink:NamedThing	DNA-templated transcriptional start site selection	Any process involved in the selection of the specific location within the template strand of a DNA-dependent RNA polymerase promoter for hybridization of the cognate ribonucleotides and formation of first phosphodiester bond within the nascent transcript.	tmpzr1t_l9r_go_relaxed.owl	DNA-dependent transcriptional start site selection|transcriptional start site selection at bacterial-type RNA polymerase promoter							krc	2011-06-20T12:44:11Z			GO:0001176		biological_process											owl:Class	
GO:0080053	biolink:NamedThing	response to phenylalanine	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a phenylalanine stimulus.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1905179	biolink:NamedThing	negative regulation of cardiac muscle tissue regeneration	Any process that stops, prevents or reduces the frequency, rate or extent of cardiac muscle tissue regeneration.	tmpzr1t_l9r_go_relaxed.owl	down regulation of cardiac muscle tissue regeneration|down-regulation of cardiac muscle tissue regeneration|inhibition of cardiac muscle tissue regeneration|downregulation of cardiac muscle tissue regeneration							rph	2016-05-05T11:30:57Z					biological_process											owl:Class	
GO:0060678	biolink:NamedThing	dichotomous subdivision of terminal units involved in ureteric bud branching	The process in which a ureteric bud bifurcates at its end.	tmpzr1t_l9r_go_relaxed.owl	bifid subdivision of terminal units involved in ureteric bud branching							dph	2009-06-02T02:18:17Z					biological_process											owl:Class	
GO:2000076	biolink:NamedThing	positive regulation of cytokinesis, site selection	Any process that activates or increases the frequency, rate or extent of site selection that occurs as part of cytokinesis.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of site selection involved in cell cycle cytokinesis							tb	2010-08-27T11:19:58Z					biological_process											owl:Class	
GO:1905743	biolink:NamedThing	calcium import into the mitochondrion involved in negative regulation of presynaptic cytosolic calcium concentration	Any mitochondrial calcium uptake that is involved in negative regulation of presynaptic cytosolic calcium concentration.	tmpzr1t_l9r_go_relaxed.owl	calcium ion transmembrane import into mitochondrion involved in negative regulation of presynaptic cytosolic calcium concentration|mitochondrial calcium uptake involved in negative regulation of presynaptic cytosolic calcium concentration							dos	2016-12-06T10:53:17Z					biological_process											owl:Class	
GO:0070335	biolink:NamedThing	aspartate binding	Binding to aspartate, the alpha-amino-acid anion of 2-aminobutanedioic acid that has formula C4H5NO4.	tmpzr1t_l9r_go_relaxed.owl	aspartic acid binding													molecular_function											owl:Class	
GO:0102951	biolink:NamedThing	indole-3-acetyl-phenylalanine synthetase activity	Catalysis of the reaction: indole-3-acetate + L-phenylalanine  + ATP = H+ + indole-3-acetyl-phenylalanine + AMP + diphosphoric acid.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-9084									molecular_function											owl:Class	
GO:0060886	biolink:NamedThing	clearance of cells from fusion plate by epithelial to mesenchymal transition	The process of epithelial to mesenchymal transition that contributes to the shaping of the semicircular canal by effectively removing epithelial cells from the fusion plate, forming the loops of the canals.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-08-13T12:34:19Z					biological_process											owl:Class	
GO:0042369	biolink:NamedThing	vitamin D catabolic process	The chemical reactions and pathways resulting in the breakdown of vitamin D, any of a group of related, fat-soluble compounds that are derived from delta-5,7 steroids and play a central role in calcium metabolism. Specific forms of vitamin D include calciferol (ergocalciferol; vitamin D2) and cholecalciferol (calciol; vitamin D3).	tmpzr1t_l9r_go_relaxed.owl	vitamin D breakdown|calciferol catabolism|vitamin D catabolism|vitamin D degradation|cholecalciferol biosynthetic process|ergocalciferol biosynthetic process|ergocalciferol biosynthesis|calciferol catabolic process|cholecalciferol biosynthesis													biological_process											owl:Class	
GO:0098910	biolink:NamedThing	regulation of atrial cardiac muscle cell action potential	Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in an atrial cardiac muscle cell contributing to the regulation of its contraction. This typically occurs via modulation of the activity or expression of voltage-gated ion channels.	tmpzr1t_l9r_go_relaxed.owl								tb	2011-11-10T08:49:13Z					biological_process											owl:Class	
GO:0052019	biolink:NamedThing	modulation by symbiont of host hormone or growth regulator levels	The alteration by an organism of the levels of hormones or growth regulators in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	modulation by organism of hormone or growth regulator levels in other organism involved in symbiotic interaction											GO:0052186		biological_process											owl:Class	
GO:0022879	biolink:NamedThing	protein-N(PI)-phosphohistidine-trehalose phosphotransferase system transporter activity	Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + trehalose(out) = protein histidine + trehalose phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.	tmpzr1t_l9r_go_relaxed.owl	trehalose PTS transporter activity													molecular_function											owl:Class	
GO:0015574	biolink:NamedThing	trehalose transmembrane transporter activity	Enables the transfer of trehalose from one side of a membrane to the other. Trehalose is the disaccharide alpha-D-glucopyranosyl-alpha-D-glucopyranoside that acts of a reserve carbohydrate in certain fungi, algae and lichens.	tmpzr1t_l9r_go_relaxed.owl	trehalose permease activity				RHEA:17629							GO:0015584		molecular_function											owl:Class	
GO:0097059	biolink:NamedThing	CNTFR-CLCF1 complex	A protein complex that is composed of two soluble ciliary neurotrophic factor receptor alpha subunits (product of the CNTFR gene) and two molecules of cardiotrophin-like cytokine factor 1 (product of the CLCF1 gene). The complex is secreted into the extracellular space.	tmpzr1t_l9r_go_relaxed.owl	sCNTFR-CLC complex							pr	2011-05-26T10:43:22Z					cellular_component											owl:Class	
GO:0061496	biolink:NamedThing	half bridge of mitotic spindle pole body	Structure adjacent to the plaques of the mitotic spindle pole body.	tmpzr1t_l9r_go_relaxed.owl								dph	2012-12-11T09:13:52Z					cellular_component											owl:Class	
GO:0005825	biolink:NamedThing	half bridge of spindle pole body	Structure adjacent to the plaques of the spindle pole body.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:1903421	biolink:NamedThing	regulation of synaptic vesicle recycling	Any process that modulates the frequency, rate or extent of synaptic vesicle recycling.	tmpzr1t_l9r_go_relaxed.owl	regulation of kiss-and-run synaptic vesicle recycling|regulation of kiss-and-stay synaptic vesicle recycling					An example of this is mouse LRRK2 (Q5S006) in PMID:21307259 inferred from mutant phenotype		pad	2014-09-09T15:27:50Z					biological_process											owl:Class	
GO:0033223	biolink:NamedThing	2-aminoethylphosphonate transport	The directed movement of 2-aminoethylphosphonate, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	2-phosphonoethylamine transport|ciliatine transport													biological_process											owl:Class	
GO:0047700	biolink:NamedThing	beta-glucoside kinase activity	Catalysis of the reaction: ATP + cellobiose = ADP + 6-phospho-beta-D-glucosyl-(1,4)-D-glucose.	tmpzr1t_l9r_go_relaxed.owl	b-glucoside kinase activity|ATP:cellobiose 6-phosphotransferase activity|beta-D-glucoside kinase (phosphorylating)				EC:2.7.1.85|MetaCyc:BETA-GLUCOSIDE-KINASE-RXN|RHEA:21944									molecular_function											owl:Class	
GO:0070182	biolink:NamedThing	DNA polymerase binding	Binding to a DNA polymerase.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0015728	biolink:NamedThing	mevalonate transport	The directed movement of mevalonate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0050191	biolink:NamedThing	phosphoglycerate kinase (GTP) activity	Catalysis of the reaction: 3-phospho-D-glycerate + GTP = 3-phospho-D-glyceroyl phosphate + GDP + H(+).	tmpzr1t_l9r_go_relaxed.owl	GTP:3-phospho-D-glycerate 1-phosphotransferase activity				RHEA:23332|EC:2.7.2.10|KEGG_REACTION:R01517|MetaCyc:PHOSPHOGLYCERATE-KINASE-GTP-RXN									molecular_function											owl:Class	
GO:1903783	biolink:NamedThing	negative regulation of sodium ion import across plasma membrane	Any process that stops, prevents or reduces the frequency, rate or extent of sodium ion import across the plasma membrane.	tmpzr1t_l9r_go_relaxed.owl	downregulation of sodium ion import across plasma membrane|down-regulation of sodium ion import across plasma membrane|inhibition of sodium ion import across plasma membrane|down regulation of sodium ion import across plasma membrane							nc	2015-01-07T16:48:51Z					biological_process											owl:Class	
GO:1903782	biolink:NamedThing	regulation of sodium ion import across plasma membrane	Any process that modulates the frequency, rate or extent of sodium ion import across the plasma membrane.	tmpzr1t_l9r_go_relaxed.owl								nc	2015-01-07T16:48:43Z					biological_process											owl:Class	
GO:0050902	biolink:NamedThing	leukocyte adhesive activation	The activation of loosely bound or rolling leukocytes by signals displayed on blood vessel endothelial cells, which is typically the second step in cellular extravasation.	tmpzr1t_l9r_go_relaxed.owl	leukocyte adhesive triggering													biological_process											owl:Class	
GO:0009032	biolink:NamedThing	thymidine phosphorylase activity	Catalysis of the reaction: thymidine + phosphate = thymine + 2-deoxy-D-ribose 1-phosphate.	tmpzr1t_l9r_go_relaxed.owl	thymidine-orthophosphate deoxyribosyltransferase activity|pyrimidine phosphorylase activity|thymidine:phosphate deoxy-alpha-D-ribosyltransferase activity|thymidine:phosphate deoxy-D-ribosyltransferase activity				MetaCyc:THYM-PHOSPH-RXN|EC:2.4.2.4|RHEA:16037									molecular_function											owl:Class	
GO:0000796	biolink:NamedThing	condensin complex	A multisubunit protein complex that plays a central role in chromosome condensation in meiosis and mitosis.	tmpzr1t_l9r_go_relaxed.owl	SMC complex|Smc2-Smc4 complex|13S condensin complex|condensin core heterodimer|condensin I complex|8S condensin complex|nuclear condensin complex	https://github.com/geneontology/go-ontology/issues/12832										GO:0005676|GO:0008620|GO:0008621|GO:0000799|GO:0061814|GO:0000797		cellular_component											owl:Class	
GO:0044815	biolink:NamedThing	DNA packaging complex	A protein complex that plays a role in the process of DNA packaging.	tmpzr1t_l9r_go_relaxed.owl								jl	2013-09-19T11:33:45Z					cellular_component											owl:Class	
GO:0003400	biolink:NamedThing	regulation of COPII vesicle coating	Any process that modulates the rate, frequency, or extent of the addition of COPII proteins and adaptor proteins to ER membranes during the formation of transport vesicles, forming a vesicle coat.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-12-17T08:38:14Z					biological_process											owl:Class	
GO:0061422	biolink:NamedThing	positive regulation of transcription from RNA polymerase II promoter in response to alkaline pH	Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a pH >7.0.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of transcription from RNA polymerase II promoter in response to alkalinity							dph	2012-01-26T12:42:21Z					biological_process											owl:Class	
GO:0042889	biolink:NamedThing	3-phenylpropionic acid transport	The directed movement of 3-phenylpropionic acid into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	3-phenylpropionate transport|HCA transport|hydrocinnamic acid transport													biological_process											owl:Class	
GO:0062234	biolink:NamedThing	platelet activating factor catabolic process	The chemical reactions and pathways resulting in the breakdown of platelet activating factor, 2-O-acetyl-1-O-octadecyl-sn-glycero-3-phosphocholine.	tmpzr1t_l9r_go_relaxed.owl	2-O-acetyl-1-O-octadecyl-sn-glycero-3-phosphocholine catabolic process|PAF catabolic process							dph	2020-03-23T15:35:49Z					biological_process											owl:Class	
GO:0098819	biolink:NamedThing	depolarization of postsynaptic membrane	A process that depolarizes a postsynaptic membrane relative to its resting potential.  This has an excitatory effect on the post-synaptic cell, moving the membrane potential towards the firing threshold.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0060955	biolink:NamedThing	neural crest-derived cardiac glial cell fate commitment	The commitment of neural crest cells to cardiac glial cell fates and their capacity to differentiate into cardiac glial cells.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-09-29T03:15:04Z					biological_process											owl:Class	
GO:0099523	biolink:NamedThing	presynaptic cytosol	The region of the cytosol consisting of all cytosol that is part of the presynapse.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:1990125	biolink:NamedThing	DiaA complex	A homotetrameric protein complex consisting of a symmetrical pair of DiaA homodimers. Facilitates DnaA binding to the origin of replication during replication initiation.	tmpzr1t_l9r_go_relaxed.owl	DiaA homotetramer							bhm	2013-06-13T14:03:54Z					cellular_component											owl:Class	
GO:0072464	biolink:NamedThing	response to meiotic spindle assembly checkpoint signaling	A process that occurs in response to signals generated as a result of meiotic spindle assembly checkpoint signaling.	tmpzr1t_l9r_go_relaxed.owl	meiotic spindle assembly checkpoint effector process|response to signal involved in meiotic spindle assembly checkpoint							mah	2010-12-09T11:37:48Z					biological_process											owl:Class	
GO:0060613	biolink:NamedThing	fat pad development	The progression of a fat pad from its initial formation to its mature structure. A fat pad is an accumulation of adipose tissue.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-05-15T12:42:08Z					biological_process											owl:Class	
GO:0004349	biolink:NamedThing	glutamate 5-kinase activity	Catalysis of the reaction: L-glutamate + ATP = L-glutamyl 5-phosphate + ADP + H(+).	tmpzr1t_l9r_go_relaxed.owl	ATP:gamma-L-glutamate phosphotransferase activity|gamma-glutamate kinase activity|glutamate kinase activity|ATP-L-glutamate 5-phosphotransferase activity|ATP:L-glutamate 5-phosphotransferase activity|gamma-glutamyl kinase activity				EC:2.7.2.11|RHEA:14877|KEGG_REACTION:R00239|MetaCyc:GLUTKIN-RXN									molecular_function											owl:Class	
GO:1900518	biolink:NamedThing	regulation of response to pullulan	Any process that modulates the frequency, rate or extent of response to pullulan.	tmpzr1t_l9r_go_relaxed.owl								tt	2012-05-02T04:11:58Z					biological_process											owl:Class	
GO:0034165	biolink:NamedThing	positive regulation of toll-like receptor 9 signaling pathway	Any process that activates or increases the frequency, rate, or extent of toll-like receptor 9 signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of TLR9 signaling pathway|positive regulation of toll-like receptor 9 signalling pathway													biological_process											owl:Class	
GO:1904795	biolink:NamedThing	positive regulation of euchromatin binding	Any process that activates or increases the frequency, rate or extent of euchromatin binding.	tmpzr1t_l9r_go_relaxed.owl	upregulation of euchromatin binding|up-regulation of euchromatin binding|activation of euchromatin binding|up regulation of euchromatin binding							nc	2015-11-09T11:43:19Z					biological_process											owl:Class	
GO:0062208	biolink:NamedThing	positive regulation of pattern recognition receptor signaling pathway	Any process that decreases the rate, frequency or extent of a pattern recognition receptor signaling pathway.	tmpzr1t_l9r_go_relaxed.owl								dph	2020-02-03T14:45:27Z					biological_process											owl:Class	
GO:0045894	biolink:NamedThing	negative regulation of mating-type specific transcription, DNA-templated	Any mating-type specific process that stops, prevents or reduces the rate of cellular DNA-templated transcription.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of mating-type specific transcription, DNA-dependent|inhibition of transcription, mating-type specific|downregulation of transcription, mating-type specific|down-regulation of transcription, mating-type specific|down regulation of transcription, mating-type specific													biological_process											owl:Class	
GO:0044256	biolink:NamedThing	protein digestion	The whole of the physical, chemical, and biochemical processes carried out by living organisms to break down ingested proteins into components that may be easily absorbed and directed into metabolism.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0007028	biolink:NamedThing	cytoplasm organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the cytoplasm. The cytoplasm is all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.	tmpzr1t_l9r_go_relaxed.owl	cytoplasm organisation|cytoplasm organization and biogenesis													biological_process											owl:Class	
GO:0006268	biolink:NamedThing	DNA unwinding involved in DNA replication	The process in which interchain hydrogen bonds between two strands of DNA are broken or 'melted', generating unpaired template strands for DNA replication.	tmpzr1t_l9r_go_relaxed.owl	DNA unwinding factor|DNA unwinding during replication					Note that this term refers to a geometric change in DNA conformation, and should not be confused with 'DNA topological change ; GO:0006265'.								biological_process											owl:Class	
GO:1905277	biolink:NamedThing	negative regulation of epithelial tube formation	Any process that stops, prevents or reduces the frequency, rate or extent of epithelial tube formation.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of epithelial tube formation|inhibition of epithelial tube formation|down regulation of epithelial tube formation|downregulation of epithelial tube formation					An example of this is MMRN2 in human (Q9H8L6) in PMID:25745997 (inferred from direct assay).		bhm	2016-06-20T09:35:49Z					biological_process											owl:Class	
GO:0052836	biolink:NamedThing	inositol 5-diphosphate pentakisphosphate 5-kinase activity	Catalysis of the reaction: ATP + inositol 5-diphosphate pentakisphosphate = ADP + inositol 5-triphosphate pentakisphosphate.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-1855224|Reactome:R-HSA-1855158			ai	2011-11-29T01:14:22Z					molecular_function											owl:Class	
GO:0140124	biolink:NamedThing	positive regulation of Lewy body formation	Any process that activates or increases the frequency, rate or extent of Lewy body formation.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/14160						pg	2017-10-25T07:10:14Z					biological_process											owl:Class	
GO:0090261	biolink:NamedThing	positive regulation of inclusion body assembly	Any process that increases the rate, frequency, or extent of inclusion body assembly. Inclusion body assembly is the aggregation, arrangement and bonding together of a set of components to form an inclusion body.	tmpzr1t_l9r_go_relaxed.owl								tb	2010-02-03T04:23:54Z					biological_process											owl:Class	
GO:0015633	biolink:NamedThing	ABC-type zinc transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Zn2+(out) = ADP + phosphate + Zn2+(in).	tmpzr1t_l9r_go_relaxed.owl	ATP-dependent zinc transmembrane transporter activity|zinc porter activity|ATPase-coupled zinc transmembrane transporter activity|zinc-transporting ATPase activity|zinc transporting ATPase activity				RHEA:29795|EC:7.2.2.20									molecular_function											owl:Class	
GO:1900610	biolink:NamedThing	F-9775A catabolic process	The chemical reactions and pathways resulting in the breakdown of F-9775A.	tmpzr1t_l9r_go_relaxed.owl	F-9775A breakdown|F-9775A catabolism|F-9775A degradation							di	2012-05-15T07:02:49Z					biological_process											owl:Class	
GO:0009431	biolink:NamedThing	bacterial-type flagellum basal body, MS ring	One of the rings of the bacterial-type flagellar basal body; a double-flanged ring that anchors the basal body to the cytoplasmic membrane.	tmpzr1t_l9r_go_relaxed.owl	flagellin-based flagellum basal body, MS ring|flagellar basal body, MS ring|flagellar basal body, mounting plate											GO:0009430		cellular_component											owl:Class	
GO:0021856	biolink:NamedThing	hypothalamic tangential migration using cell-axon interactions	The movement of a hypothalamic neuronal precursor tangentially through the forebrain using an interaction of the migrating cells with axons of other neurons.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0045931	biolink:NamedThing	positive regulation of mitotic cell cycle	Any process that activates or increases the rate or extent of progression through the mitotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl	stimulation of progression through mitotic cell cycle|upregulation of progression through mitotic cell cycle|positive regulation of mitotic cell cycle progression|up-regulation of progression through mitotic cell cycle|positive regulation of progression through mitotic cell cycle|up regulation of progression through mitotic cell cycle|activation of progression through mitotic cell cycle													biological_process											owl:Class	
GO:0102977	biolink:NamedThing	nitrilotriacetate monooxygenase activity (FMN-dependent)	Catalysis of the reaction: nitrilotriacetate + O2 + FMNH2 = ammoniodiacetate + 2-oxo monocarboxylic acid anion + H2O + FMN.	tmpzr1t_l9r_go_relaxed.owl					EC:1.14.14.10|MetaCyc:RXN-9508|RHEA:31359									molecular_function											owl:Class	
GO:0090610	biolink:NamedThing	bundle sheath cell fate specification	The process in which a cell becomes capable of differentiating autonomously into a bundle sheath cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.	tmpzr1t_l9r_go_relaxed.owl								tb	2014-09-26T13:17:05Z					biological_process											owl:Class	
GO:1903446	biolink:NamedThing	geraniol metabolic process	The chemical reactions and pathways involving geraniol.	tmpzr1t_l9r_go_relaxed.owl	geraniol metabolism							di	2014-09-19T08:18:34Z					biological_process											owl:Class	
GO:0006651	biolink:NamedThing	diacylglycerol biosynthetic process	The chemical reactions and pathways resulting in the formation of diacylglycerol, a glyceride in which any two of the R groups (positions not specified) are acyl groups while the remaining R group can be either H or an alkyl group.	tmpzr1t_l9r_go_relaxed.owl	diacylglycerol anabolism|diglyceride biosynthesis|diacylglycerol biosynthesis|diacylglycerol synthesis|diacylglycerol formation													biological_process											owl:Class	
GO:0046463	biolink:NamedThing	acylglycerol biosynthetic process	The chemical reactions and pathways resulting in the formation of acylglycerol, any mono-, di- or triester of glycerol with (one or more) fatty acids.	tmpzr1t_l9r_go_relaxed.owl	acylglycerol synthesis|acylglycerol biosynthesis|acylglycerol anabolism|acylglycerol formation													biological_process											owl:Class	
GO:1904188	biolink:NamedThing	negative regulation of transformation of host cell by virus	Any process that stops, prevents or reduces the frequency, rate or extent of transformation of host cell by virus.	tmpzr1t_l9r_go_relaxed.owl	downregulation of transformation of host cell by virus|down-regulation of viral transformation of host cell|downregulation of viral transformation of host cell|down-regulation of transformation of host cell by virus|inhibition of viral transformation|down regulation of viral transformation of host cell|negative regulation of viral transformation|negative regulation of viral transformation of host cell|inhibition of viral transformation of host cell|inhibition of transformation of host cell by virus|down regulation of transformation of host cell by virus|down-regulation of viral transformation|down regulation of viral transformation|downregulation of viral transformation							pga	2015-05-05T15:30:04Z					biological_process											owl:Class	
GO:0014860	biolink:NamedThing	neurotransmitter secretion involved in regulation of skeletal muscle contraction	The regulated release of neurotransmitter into the synaptic cleft involved in skeletal muscle contraction. A neurotransmitter is any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell. Among the many substances that have the properties of a neurotransmitter are acetylcholine, noradrenaline, adrenaline, dopamine, glycine, gamma aminobutyrate, glutamic acid, substance P, enkephalins, endorphins and serotonin.	tmpzr1t_l9r_go_relaxed.owl	neurotransmitter secretion involved in control of skeletal muscle contraction													biological_process											owl:Class	
GO:0010464	biolink:NamedThing	regulation of mesenchymal cell proliferation	Any process that modulates the frequency, rate or extent of mesenchymal cell proliferation. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0021947	biolink:NamedThing	outward migration of deep nuclear neurons	The directed movement of a deep nuclear neuron from their ventrolateral origin to a rostrodorsal region of the cerebellar plate.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0030660	biolink:NamedThing	Golgi-associated vesicle membrane	The lipid bilayer surrounding a vesicle associated with the Golgi apparatus.	tmpzr1t_l9r_go_relaxed.owl	Golgi vesicle membrane													cellular_component											owl:Class	
GO:0006860	biolink:NamedThing	extracellular amino acid transport	The directed extracellular movement of amino acids.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0046191	biolink:NamedThing	aerobic phenol-containing compound catabolic process	The chemical reactions and pathways resulting in the breakdown of a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring, in the presence of oxygen.	tmpzr1t_l9r_go_relaxed.owl	aerobic phenol-containing compound breakdown|aerobic phenol-containing compound degradation|aerobic phenol-containing compound catabolism													biological_process											owl:Class	
GO:0071044	biolink:NamedThing	histone mRNA catabolic process	The chemical reactions and pathways resulting in the breakdown of histone messenger RNA (mRNA).	tmpzr1t_l9r_go_relaxed.owl								krc	2009-07-30T09:48:10Z					biological_process											owl:Class	
GO:1904823	biolink:NamedThing	purine nucleobase transmembrane transport	The process in which a purine nucleobase is transported across a membrane.	tmpzr1t_l9r_go_relaxed.owl								vw	2015-11-19T09:07:56Z					biological_process											owl:Class	
GO:2001295	biolink:NamedThing	malonyl-CoA biosynthetic process	The chemical reactions and pathways resulting in the formation of malonyl-CoA, the S-malonyl derivative of coenzyme A.	tmpzr1t_l9r_go_relaxed.owl	malonyl-CoA biosynthesis|malonyl-CoA synthesis|malonyl-CoA anabolism|malonyl-CoA formation							pr	2012-02-14T02:23:21Z					biological_process											owl:Class	
GO:0043401	biolink:NamedThing	steroid hormone mediated signaling pathway	A series of molecular signals mediated by a steroid hormone binding to a receptor.	tmpzr1t_l9r_go_relaxed.owl	steroid hormone mediated signalling													biological_process											owl:Class	
GO:0035009	biolink:NamedThing	negative regulation of melanization defense response	Any process that reduces the rate or extent of the melanization defense response. This regulation is critical to limit melanization to the site of injury or infection.	tmpzr1t_l9r_go_relaxed.owl	down regulation of melanization defense response|inhibition of melanization defense response|negative regulation of melanization defence response|downregulation of melanization defense response|down-regulation of melanization defense response													biological_process											owl:Class	
GO:0021869	biolink:NamedThing	forebrain ventricular zone progenitor cell division	The mitotic division of a basal progenitor giving rise to two neurons.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:2000408	biolink:NamedThing	negative regulation of T cell extravasation	Any process that stops, prevents or reduces the frequency, rate or extent of T cell extravasation.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of T-lymphocyte extravasation|negative regulation of T-cell extravasation|negative regulation of T lymphocyte extravasation							mah	2011-02-23T10:52:28Z					biological_process											owl:Class	
GO:0042184	biolink:NamedThing	xylene catabolic process	The chemical reactions and pathways resulting in the breakdown of xylene, a mixture of three colorless, aromatic hydrocarbon liquids, ortho-, meta- and para-xylene.	tmpzr1t_l9r_go_relaxed.owl	xylene breakdown|xylene catabolism|xylene degradation													biological_process											owl:Class	
GO:0019564	biolink:NamedThing	aerobic glycerol catabolic process	The chemical reactions and pathways resulting in the breakdown of glycerol, 1,2,3-propanetriol, in the presence of oxygen.	tmpzr1t_l9r_go_relaxed.owl	aerobic glycerol breakdown|aerobic glycerol catabolism|aerobic glycerol fermentation|aerobic glycerol degradation				MetaCyc:PWY0-381							GO:0019565		biological_process											owl:Class	
GO:0071853	biolink:NamedThing	fungal-type cell wall disassembly	A cellular process that results in the breakdown of a fungal-type cell wall.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-09-10T03:10:47Z					biological_process											owl:Class	
GO:1900654	biolink:NamedThing	positive regulation of demethylkotanin biosynthetic process	Any process that activates or increases the frequency, rate or extent of demethylkotanin biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	up regulation of demethylkotanin anabolism|up regulation of demethylkotanin biosynthesis|up regulation of demethylkotanin synthesis|up regulation of demethylkotanin biosynthetic process|activation of demethylkotanin anabolism|up-regulation of demethylkotanin biosynthesis|upregulation of demethylkotanin synthesis|positive regulation of demethylkotanin biosynthesis|up-regulation of demethylkotanin synthesis|upregulation of demethylkotanin biosynthesis|up regulation of demethylkotanin formation|activation of demethylkotanin biosynthetic process|upregulation of demethylkotanin formation|activation of demethylkotanin synthesis|up-regulation of demethylkotanin biosynthetic process|activation of demethylkotanin formation|up-regulation of demethylkotanin formation|activation of demethylkotanin biosynthesis|positive regulation of demethylkotanin synthesis|positive regulation of demethylkotanin anabolism|up-regulation of demethylkotanin anabolism|upregulation of demethylkotanin anabolism|upregulation of demethylkotanin biosynthetic process|positive regulation of demethylkotanin formation							di	2012-05-22T04:07:49Z					biological_process											owl:Class	
GO:2000917	biolink:NamedThing	positive regulation of glucuronoxylan catabolic process	Any process that activates or increases the frequency, rate or extent of glucuronoxylan catabolic process.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of glucuronoxylan catabolism							tt	2011-07-29T07:54:50Z					biological_process											owl:Class	
GO:0120218	biolink:NamedThing	host interaction involved in quorum sensing	A quorum sensing process that is modulated by some interaction with a host cell or organism.	tmpzr1t_l9r_go_relaxed.owl								krc	2019-11-01T21:52:08Z					biological_process											owl:Class	
GO:0014709	biolink:NamedThing	positive regulation of somitomeric trunk muscle development	Any process that activates, maintains or increases the frequency, rate or extent of somitomeric trunk muscle development. The somitomeric trunk muscle is derived from somitomeric mesoderm. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0009399	biolink:NamedThing	nitrogen fixation	The process in which nitrogen is taken from its relatively inert molecular form (N2) in the atmosphere and converted into nitrogen compounds useful for other chemical processes, such as ammonia, nitrate and nitrogen dioxide.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Nitrogen_fixation|MetaCyc:N2FIX-PWY									biological_process											owl:Class	
GO:0050212	biolink:NamedThing	progesterone 11-alpha-monooxygenase activity	Catalysis of the reaction: AH(2) + O(2) + progesterone = 11alpha-hydroxyprogesterone + A + H(2)O.	tmpzr1t_l9r_go_relaxed.owl	progesterone,hydrogen-donor:oxygen oxidoreductase (11alpha-hydroxylating)|progesterone 11alpha-hydroxylase activity|progesterone 11-alpha-hydroxylase activity|progesterone 11a-monooxygenase activity|progesterone 11alpha-monooxygenase activity				KEGG_REACTION:R02214|EC:1.14.99.14|RHEA:18205|MetaCyc:PROGESTERONE-11-ALPHA-MONOOXYGENASE-RXN									molecular_function											owl:Class	
GO:0046304	biolink:NamedThing	2-nitropropane catabolic process	The chemical reactions and pathways resulting in the breakdown of 2-nitropropane, a clear, colorless liquid with a mild, fruity odor.	tmpzr1t_l9r_go_relaxed.owl	2-nitropropane breakdown|2-nitropropane catabolism|2-nitropropane degradation													biological_process											owl:Class	
GO:0044472	biolink:NamedThing	envenomation resulting in modulation of calcium channel activity in other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with a resultant change in the activity of a calcium channel in the bitten organism.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-01-19T02:17:25Z					biological_process											owl:Class	
GO:2000920	biolink:NamedThing	positive regulation of glucuronoarabinoxylan catabolic process	Any process that activates or increases the frequency, rate or extent of glucuronoarabinoxylan catabolic process.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of glucuronoarabinoxylan catabolism							tt	2011-08-01T12:36:58Z					biological_process											owl:Class	
GO:0140647	biolink:NamedThing	P450-containing electron transport chain	A electron transport chain in which one or more electron carriers operate to transfer electrons from donors to a cytochrome P450 protein or domain. Electron carriers operating in this chain include FAD-containing flavoproteins or domains, FMN domains, ferredoxins and cytochrome b5. The reduced cytochrome P450 functions as the terminal oxidase and participates in a wide range of biochemical pathways.	tmpzr1t_l9r_go_relaxed.owl	P450-containing system	https://github.com/geneontology/go-ontology/issues/21455			Wikipedia:P450-containing_systems			pg	2021-05-21T08:34:01Z					biological_process											owl:Class	
GO:1903477	biolink:NamedThing	mitotic contractile ring actin filament bundle assembly	Any actin filament bundle assembly that is involved in mitotic actomyosin contractile ring assembly.	tmpzr1t_l9r_go_relaxed.owl	actin filament bundle assembly involved in mitotic actomyosin contractile ring assembly							vw	2014-09-23T14:56:01Z					biological_process											owl:Class	
GO:0043028	biolink:NamedThing	cysteine-type endopeptidase regulator activity involved in apoptotic process	Binds to and modulates the activity of a cysteine-type endopeptidase involved in the apoptotic process.	tmpzr1t_l9r_go_relaxed.owl	caspase regulator activity													molecular_function											owl:Class	
GO:0045492	biolink:NamedThing	xylan biosynthetic process	The chemical reactions and pathways resulting in the formation of xylan, a polymer containing a beta-1,4-linked D-xylose backbone.	tmpzr1t_l9r_go_relaxed.owl	xylan biosynthesis|xylan formation|xylan anabolism|xylan synthesis													biological_process											owl:Class	
GO:0010865	biolink:NamedThing	stipule development	The process whose specific outcome is the progression of the stipule over time, from its formation to the mature structure. A stipule is one of (usually) a pair of appendages at the bases of leaves in many broad-leaved angiosperms.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0008201	biolink:NamedThing	heparin binding	Binding to heparin, a member of a group of glycosaminoglycans found mainly as an intracellular component of mast cells and which consist predominantly of alternating alpha-(1->4)-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues.	tmpzr1t_l9r_go_relaxed.owl	heparan sulfate binding													molecular_function											owl:Class	
GO:0062054	biolink:NamedThing	fluoride channel activity	Enables the facilitated diffusion of fluoride (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.	tmpzr1t_l9r_go_relaxed.owl								dph	2018-06-25T13:30:23Z					molecular_function											owl:Class	
GO:0005253	biolink:NamedThing	anion channel activity	Enables the energy-independent passage of anions across a lipid bilayer down a concentration gradient.	tmpzr1t_l9r_go_relaxed.owl	non-selective anion channel activity				Reactome:R-HSA-432034|Reactome:R-HSA-432036									molecular_function											owl:Class	
GO:2001119	biolink:NamedThing	methanofuran metabolic process	The chemical reactions and pathways involving a methanofuran.	tmpzr1t_l9r_go_relaxed.owl	methanofuran metabolism							jl	2011-10-11T12:34:08Z					biological_process											owl:Class	
GO:0002852	biolink:NamedThing	regulation of T cell mediated cytotoxicity directed against tumor cell target	Any process that modulates the frequency, rate, or extent of T cell mediated cytotoxicity directed against a tumor cell target.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0018955	biolink:NamedThing	phenanthrene metabolic process	The chemical reactions and pathways involving phenanthrene, a tricyclic aromatic hydrocarbon used in explosives and in the synthesis of dyes and drugs. Although phenanthrene is not mutagenic or carcinogenic, it has been shown to be toxic to marine diatoms, gastropods, mussels, crustaceans, and fish.	tmpzr1t_l9r_go_relaxed.owl	phenanthrene metabolism				UM-BBD_pathwayID:pha									biological_process											owl:Class	
GO:1905424	biolink:NamedThing	regulation of Wnt-mediated midbrain dopaminergic neuron differentiation	Any process that modulates the frequency, rate or extent of Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation.	tmpzr1t_l9r_go_relaxed.owl	regulation of Wingless signalling pathway involved in DA neurogenesis from midbrain floor plate|regulation of Wingless signaling pathway involved in mDA neuron differentiation|regulation of Wingless signaling pathway involved in DA neurogenesis from midbrain floor plate|regulation of Wg signalling pathway involved in midbrain DA neurogenesis|regulation of frizzled signalling pathway involved in midbrain DA neurogenesis|regulation of frizzled signalling pathway involved in midbrain dopaminergic neuron differentiation|regulation of Wg signaling pathway involved in midbrain DA neurogenesis|regulation of Wg signaling pathway involved in DA neurogenesis from midbrain floor plate|regulation of Wnt receptor signaling pathway involved in midbrain DA neurogenesis|regulation of frizzled signaling pathway involved in mDA neuron differentiation|regulation of Wg signalling pathway involved in mDA neuron differentiation|regulation of frizzled signalling pathway involved in DA neurogenesis from midbrain floor plate|regulation of frizzled signaling pathway involved in midbrain dopaminergic neuron production|regulation of Wingless signalling pathway involved in midbrain DA neurogenesis|regulation of Wnt receptor signalling pathway involved in DA neurogenesis from midbrain floor plate|regulation of Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation|regulation of Wnt-activated signaling pathway involved in DA neurogenesis from midbrain floor plate|regulation of Wnt-activated signaling pathway involved in midbrain dopaminergic neuron production|regulation of Wnt signaling pathway involved in midbrain dopaminergic neuron production|regulation of Wnt receptor signalling pathway involved in mDA neuron differentiation|regulation of Wnt-activated signaling pathway involved in midbrain dopaminergic neuron differentiation|regulation of Wg signalling pathway involved in midbrain dopaminergic neuron differentiation|regulation of Wnt signaling pathway involved in mDA neuron differentiation|regulation of Wnt receptor signalling pathway involved in midbrain dopaminergic neuron production|regulation of Wnt receptor signaling pathway involved in mDA neuron differentiation|regulation of Wnt receptor signaling pathway involved in midbrain dopaminergic neuron production|regulation of Wnt-mediated midbrain DA neuron differentiation|regulation of Wg signalling pathway involved in midbrain dopaminergic neuron production|regulation of Wnt receptor signalling pathway involved in midbrain DA neurogenesis|regulation of Wingless signaling pathway involved in midbrain dopaminergic neuron production|regulation of midbrain dopaminergic neuron differentiation by regulation of Wnt signaling|regulation of Wnt receptor signalling pathway involved in midbrain dopaminergic neuron differentiation|regulation of frizzled signaling pathway involved in DA neurogenesis from midbrain floor plate|regulation of Wingless signalling pathway involved in midbrain dopaminergic neuron production|regulation of Wnt-activated signaling pathway involved in midbrain DA neurogenesis|regulation of Wingless signalling pathway involved in mDA neuron differentiation|regulation of Wg signaling pathway involved in mDA neuron differentiation|regulation of Wnt signaling pathway involved in DA neurogenesis from midbrain floor plate|regulation of Wingless signaling pathway involved in midbrain DA neurogenesis|regulation of Wg signalling pathway involved in DA neurogenesis from midbrain floor plate|regulation of Wg signaling pathway involved in midbrain dopaminergic neuron differentiation|regulation of Wnt receptor signaling pathway involved in midbrain dopaminergic neuron differentiation|regulation of frizzled signalling pathway involved in mDA neuron differentiation|regulation of Wnt signaling pathway involved in midbrain DA neurogenesis|regulation of frizzled signalling pathway involved in midbrain dopaminergic neuron production|regulation of Wingless signaling pathway involved in midbrain dopaminergic neuron differentiation|regulation of frizzled signaling pathway involved in midbrain dopaminergic neuron differentiation|regulation of frizzled signaling pathway involved in midbrain DA neurogenesis|regulation of Wnt-activated signaling pathway involved in mDA neuron differentiation|regulation of Wingless signalling pathway involved in midbrain dopaminergic neuron differentiation|regulation of Wnt receptor signaling pathway involved in DA neurogenesis from midbrain floor plate|regulation of Wg signaling pathway involved in midbrain dopaminergic neuron production							bf	2016-09-07T10:03:36Z					biological_process											owl:Class	
GO:2001027	biolink:NamedThing	negative regulation of endothelial cell chemotaxis	Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell chemotaxis.	tmpzr1t_l9r_go_relaxed.owl								rl	2011-08-22T01:07:31Z					biological_process											owl:Class	
GO:0102178	biolink:NamedThing	4alpha-formyl-ergosta-7,24(241)-dien-3beta-ol-methyl oxidase activity	Catalysis of the reaction: 4alpha-formyl-ergosta-7,24(241)-dien-3beta-ol + O2 + NADH <=> 4alpha-carboxy-ergosta-7,24(241)-dien-3beta-ol + NAD + H2O.	tmpzr1t_l9r_go_relaxed.owl					RHEA:58880|MetaCyc:RXN-11932									molecular_function											owl:Class	
GO:0005534	biolink:NamedThing	galactose binding	Binding to aldohexose galactose (galacto-hexose), a common constituent of many oligo- and polysaccharides.	tmpzr1t_l9r_go_relaxed.owl	galactose binding lectin													molecular_function											owl:Class	
GO:1902236	biolink:NamedThing	negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway	Any process that stops, prevents or reduces the frequency, rate or extent of an endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	downregulation of endoplasmic reticulum stress-induced apoptosis|down regulation of apoptosis in response to ER stress|inhibition of ER stress-induced apoptosis|down-regulation of intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress|inhibition of endoplasmic reticulum stress-induced apoptosis|down regulation of intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress|down-regulation of endoplasmic reticulum stress-induced apoptosis|negative regulation of apoptosis triggered by ER stress|negative regulation of intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress|inhibition of intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress|negative regulation of ER stress-induced apoptosis|down regulation of endoplasmic reticulum stress-induced apoptosis|downregulation of intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress|downregulation of ER stress-induced apoptosis|inhibition of apoptosis triggered by ER stress|inhibition of intrinsic apoptotic signaling pathway induced by endoplasmic reticulum stress|down-regulation of apoptosis in response to ER stress|down-regulation of ER stress-induced apoptosis|downregulation of intrinsic apoptotic signaling pathway induced by endoplasmic reticulum stress|negative regulation of intrinsic apoptotic signaling pathway induced by endoplasmic reticulum stress|downregulation of apoptosis in response to ER stress|negative regulation of endoplasmic reticulum stress-induced apoptosis|down-regulation of intrinsic apoptotic signaling pathway induced by endoplasmic reticulum stress|negative regulation of apoptosis in response to ER stress|inhibition of apoptosis in response to ER stress|down regulation of apoptosis triggered by ER stress|down-regulation of apoptosis triggered by ER stress|down regulation of ER stress-induced apoptosis|down regulation of intrinsic apoptotic signaling pathway induced by endoplasmic reticulum stress|downregulation of apoptosis triggered by ER stress							rl	2013-06-18T15:19:43Z					biological_process											owl:Class	
GO:0032974	biolink:NamedThing	amino acid transmembrane export from vacuole	The directed movement of amino acids out of the vacuole, across the vacuolar membrane.	tmpzr1t_l9r_go_relaxed.owl	amino acid efflux from vacuole|vacuolar amino acid export													biological_process											owl:Class	
GO:0046117	biolink:NamedThing	queuosine catabolic process	The chemical reactions and pathways resulting in the breakdown of queuosines, any of a series of nucleosides found in tRNA and having an additional pentenyl ring added via an NH group to the methyl group of 7-methylguanosine. The pentenyl ring may carry other substituents.	tmpzr1t_l9r_go_relaxed.owl	queuosine catabolism|queuosine breakdown|queuosine degradation													biological_process											owl:Class	
GO:0044000	biolink:NamedThing	movement in host	The process in which an organism or its progeny spreads from one location to another within its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	movement of symbiont in host|symbiont movement within host|symbiont movement in host|movement of symbiont within host|movement within host													biological_process											owl:Class	
GO:0052126	biolink:NamedThing	movement in host environment	The directed movement of an organism or motile cell on, within or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	movement in response to host													biological_process											owl:Class	
GO:0018961	biolink:NamedThing	pentachlorophenol metabolic process	The chemical reactions and pathways involving pentachlorophenol, a chlorinated insecticide and fungicide used primarily to protect timber from fungal rot and wood boring insects. Pentachlorophenol is significantly toxic to mammals, plants, and many microorganisms.	tmpzr1t_l9r_go_relaxed.owl	PCP metabolic process|pentachlorophenol metabolism|PCP metabolism				UM-BBD_pathwayID:pcp									biological_process											owl:Class	
GO:1903140	biolink:NamedThing	regulation of establishment of endothelial barrier	Any process that modulates the frequency, rate or extent of establishment of endothelial barrier.	tmpzr1t_l9r_go_relaxed.owl								als	2014-07-01T12:12:34Z					biological_process											owl:Class	
GO:2000183	biolink:NamedThing	negative regulation of progesterone biosynthetic process	Any process that stops, prevents, or reduces the frequency, rate or extent of progesterone biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of progesterone formation|negative regulation of progesterone biosynthesis|negative regulation of progesterone anabolism|negative regulation of progesterone synthesis							dph	2010-10-14T07:36:10Z					biological_process											owl:Class	
GO:0000175	biolink:NamedThing	3'-5'-exoribonuclease activity	Catalysis of the sequential cleavage of mononucleotides from a free 3' terminus of an RNA molecule.	tmpzr1t_l9r_go_relaxed.owl	3'-5' exoribonuclease activity				Reactome:R-HSA-6791227|Reactome:R-HSA-9694632|Reactome:R-HSA-9682603|Reactome:R-HSA-430028|Reactome:R-HSA-6791222|EC:3.1.13.-									molecular_function											owl:Class	
GO:0008408	biolink:NamedThing	3'-5' exonuclease activity	Catalysis of the hydrolysis of ester linkages within nucleic acids by removing nucleotide residues from the 3' end.	tmpzr1t_l9r_go_relaxed.owl	3'-5'-exonuclease activity				Reactome:R-HSA-3245943									molecular_function											owl:Class	
GO:0006171	biolink:NamedThing	cAMP biosynthetic process	The chemical reactions and pathways resulting in the formation of the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate).	tmpzr1t_l9r_go_relaxed.owl	cyclic AMP biosynthetic process|cAMP anabolism|3',5'-cAMP biosynthesis|3',5' cAMP biosynthetic process|adenosine 3',5'-cyclophosphate biosynthetic process|cAMP biosynthesis|cAMP formation|3',5'-cAMP biosynthetic process|cyclic AMP biosynthesis|cAMP synthesis|3',5' cAMP biosynthesis|adenosine 3',5'-cyclophosphate biosynthesis													biological_process											owl:Class	
GO:0043808	biolink:NamedThing	lyso-ornithine lipid acyltransferase activity	Catalysis of the reaction: lyso-ornithine lipid + acyl-[acyl-carrier protein] = ornithine lipid + [acyl-carrier protein].	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1901316	biolink:NamedThing	positive regulation of histone H2A K63-linked ubiquitination	Any process that activates or increases the frequency, rate or extent of histone H2A K63-linked ubiquitination.	tmpzr1t_l9r_go_relaxed.owl	up regulation of histone H2A K63-linked ubiquitination|up-regulation of histone H2A K63-linked ubiquitination|upregulation of histone H2A K63-linked ubiquitination|activation of histone H2A K63-linked ubiquitination							tb	2012-08-22T20:29:32Z					biological_process											owl:Class	
GO:0032108	biolink:NamedThing	negative regulation of response to nutrient levels	Any process that stops, prevents, or reduces the frequency, rate or extent of a response to nutrient levels.	tmpzr1t_l9r_go_relaxed.owl	down regulation of response to nutrient levels|down-regulation of response to nutrient levels|inhibition of response to nutrient levels|downregulation of response to nutrient levels													biological_process											owl:Class	
GO:0089704	biolink:NamedThing	L-glutamate transmembrane export from vacuole	The directed movement of L-glutamate out of the vacuole, across the vacuolar membrane.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1990114	biolink:NamedThing	RNA polymerase II core complex assembly	The aggregation, arrangement and bonding together of a set of components to form the eukaryotic RNA polymerase II core complex.	tmpzr1t_l9r_go_relaxed.owl	RNA Polymerase II assembly|DNA-directed RNA polymerase II, core complex assembly							rb	2013-05-31T21:46:42Z					biological_process											owl:Class	
GO:2000373	biolink:NamedThing	positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity	Any process that activates or increases the frequency, rate or extent of DNA topoisomerase (ATP-hydrolyzing) activity.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of DNA topoisomerase II|positive regulation of deoxyribonucleate topoisomerase|positive regulation of DNA topoisomerase type II activity|positive regulation of topoisomerase II|positive regulation of DNA topoisomerase (ATP-hydrolysing)|positive regulation of type II DNA topoisomerase activity|positive regulation of topoisomerase|positive regulation of DNA topoisomerase IV activity|positive regulation of deoxyribonucleic topoisomerase activity							mah	2011-02-09T02:35:43Z					biological_process											owl:Class	
GO:0003239	biolink:NamedThing	conus arteriosus morphogenesis	The process in which the conus arteriosus is generated and organized. The conus arteriosus is a valved chamber with thick muscular walls stemming from the ventricle and connecting to the pulmonary trunk.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-10-13T11:25:04Z					biological_process											owl:Class	
GO:0070785	biolink:NamedThing	negative regulation of growth of unicellular organism as a thread of attached cells	Any process that decreases the frequency, rate or extent of the process in which cells remain attached after division and form thread-like filaments that may penetrate into a solid growth medium.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-07-07T02:37:21Z					biological_process											owl:Class	
GO:0035588	biolink:NamedThing	G protein-coupled purinergic receptor signaling pathway	The series of molecular signals generated as a consequence of a receptor binding to an extracellular purine or purine derivative and transmitting the signal to a heterotrimeric G-protein complex to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	G-protein coupled purinergic receptor signalling pathway|G-protein coupled purinergic receptor signaling pathway							bf	2010-10-22T11:11:53Z					biological_process											owl:Class	
GO:1902441	biolink:NamedThing	protein localization to meiotic spindle pole body	A process in which a protein is transported to, or maintained in, a location within a meiotic spindle pole body.	tmpzr1t_l9r_go_relaxed.owl	protein location to meiotic spindle pole body|protein localisation in meiotic spindle pole body|protein localization in meiotic spindle pole body|protein localisation to meiotic spindle pole body|establishment of protein localization to meiotic spindle pole body							mah	2013-10-10T14:45:04Z			GO:1990945|GO:1990954		biological_process											owl:Class	
GO:0099189	biolink:NamedThing	postsynaptic spectrin-associated cytoskeleton	The portion of the spectrin-associated cytoskeleton contained within the postsynapse.	tmpzr1t_l9r_go_relaxed.owl								dos	2017-12-20T15:29:09Z					cellular_component											owl:Class	
GO:0001579	biolink:NamedThing	medium-chain fatty acid transport	The directed movement of medium-chain fatty acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A medium-chain fatty acid is a fatty acid with a chain length of between C6 and C12.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0008932	biolink:NamedThing	lytic endotransglycosylase activity	Catalysis of the specific cleavage of the beta-(1->4) glycosidic linkage between N-acetylmuramyl and N-acetylglucosaminyl residues in peptidoglycan, with the concomitant formation of 1,6-anhydro-N-acetylmuramyl residues. Acts on linkages within peptidoglycan chains (i.e. not at the ends) to produce shorter strands with 1,6-anhydromuramic acid ends.	tmpzr1t_l9r_go_relaxed.owl	murein lytic endotransglycosylase E activity				EC:2.4.99.-									molecular_function											owl:Class	
GO:0008933	biolink:NamedThing	lytic transglycosylase activity	Catalysis of the specific cleavage of the beta-(1->4) glycosidic linkage between N-acetylmuramyl and N-acetylglucosaminyl residues in peptidoglycan, with the concomitant formation of 1,6-anhydro-N-acetylmuramyl residues.	tmpzr1t_l9r_go_relaxed.owl	peptidoglycan lytic transglycosylase activity|murein transglycosylase B activity				EC:3.2.1.-									molecular_function											owl:Class	
GO:0046116	biolink:NamedThing	queuosine metabolic process	The chemical reactions and pathways involving queuosines, any of a series of nucleosides found in tRNA and having an additional pentenyl ring added via an NH group to the methyl group of 7-methylguanosine. The pentenyl ring may carry other substituents.	tmpzr1t_l9r_go_relaxed.owl	queuosine metabolism													biological_process											owl:Class	
GO:0002554	biolink:NamedThing	serotonin secretion by platelet	The regulated release of serotonin by a platelet or group of platelets.	tmpzr1t_l9r_go_relaxed.owl	serotonin release by platelet													biological_process											owl:Class	
GO:2000298	biolink:NamedThing	regulation of Rho-dependent protein serine/threonine kinase activity	Any process that modulates the frequency, rate or extent of Rho-dependent protein serine/threonine kinase activity.	tmpzr1t_l9r_go_relaxed.owl	regulation of Rho-associated protein kinase activity|regulation of ROCK kinase activity							mah	2010-12-23T11:44:50Z					biological_process											owl:Class	
GO:0071900	biolink:NamedThing	regulation of protein serine/threonine kinase activity	Any process that modulates the rate, frequency, or extent of protein serine/threonine kinase activity.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-09-15T03:08:35Z					biological_process											owl:Class	
GO:0061823	biolink:NamedThing	ring centriole	A ring-like structure observed at the base of the ciliary cap of insect spermatids. This structure may anchor the axoneme to the ciliary cap membrane and/or act as a diffusion barrier, proposed to be analogous to the annulus of mammalian sperm flagellum.	tmpzr1t_l9r_go_relaxed.owl								dph	2017-01-14T14:18:29Z					cellular_component											owl:Class	
GO:0046474	biolink:NamedThing	glycerophospholipid biosynthetic process	The chemical reactions and pathways resulting in the formation of glycerophospholipids, any derivative of glycerophosphate that contains at least one O-acyl, O-alkyl, or O-alkenyl group attached to the glycerol residue.	tmpzr1t_l9r_go_relaxed.owl	glycerophospholipid anabolism|glycerophospholipid synthesis|glycerophospholipid biosynthesis|phosphoglyceride biosynthetic process|phosphoglyceride biosynthesis|glycerophospholipid formation													biological_process											owl:Class	
GO:0042217	biolink:NamedThing	1-aminocyclopropane-1-carboxylate catabolic process	The chemical reactions and pathways resulting in the breakdown of 1-aminocyclopropane-1-carboxylate, a natural product found in plant tissues. It is a key intermediate in the biosynthesis of ethylene (ethene), a fruit-ripening hormone in plants.	tmpzr1t_l9r_go_relaxed.owl	1-aminocyclopropane-1-carboxylate catabolism|1-aminocyclopropane-1-carboxylate breakdown|1-aminocyclopropane-1-carboxylate degradation													biological_process											owl:Class	
GO:0014848	biolink:NamedThing	urinary tract smooth muscle contraction	A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the urinary tract. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The urinary tract consists of organs of the body that produce and discharge urine. These include the kidneys, ureters, bladder, and urethra.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0090475	biolink:NamedThing	lys-lys specific dibasic protein processing	Any protein processing achieved by the cleavage of a peptide bond after two consecutive lysine amino acid residues within a protein.	tmpzr1t_l9r_go_relaxed.owl								tb	2012-10-01T10:42:30Z					biological_process											owl:Class	
GO:0090472	biolink:NamedThing	dibasic protein processing	Any protein processing achieved by the cleavage of a peptide bond after two basic amino acids within a protein.	tmpzr1t_l9r_go_relaxed.owl								tb	2012-10-01T10:39:26Z					biological_process											owl:Class	
GO:0036271	biolink:NamedThing	response to methylphenidate	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methylphenidate stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to MPD|response to ritalin|response to MPH					Note that this term is in the subset of terms that should not be used for direct manual annotation of gene products. It was created to be used for cross-referencing by other ontologies. Direct annotations to this term may be amended during annotation QC.		bf	2012-07-09T01:30:57Z					biological_process											owl:Class	
GO:0008806	biolink:NamedThing	carboxymethylenebutenolidase activity	Catalysis of the reaction: 4-carboxymethylenebut-2-en-4-olide + H2O = 4 oxohex-2-enedioate.	tmpzr1t_l9r_go_relaxed.owl	4-carboxymethylenebut-2-en-4-olide lactonohydrolase activity|dienelactone hydrolase activity|carboxymethylene butenolide hydrolase activity|maleylacetate enol-lactonase activity				UM-BBD_enzymeID:e0066|EC:3.1.1.45|RHEA:12372|MetaCyc:CARBOXYMETHYLENEBUTENOLIDASE-RXN							GO:0018735		molecular_function											owl:Class	
GO:0099146	biolink:NamedThing	intrinsic component of postsynaptic density membrane	The component of the postsynaptic density membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.	tmpzr1t_l9r_go_relaxed.owl	intrinsic to postsynaptic specialization membrane							dos	2017-07-05T10:43:24Z					cellular_component											owl:Class	
GO:0098693	biolink:NamedThing	regulation of synaptic vesicle cycle	Any process that modulates the frequency, rate or extent of the synaptic vesicle cycle.	tmpzr1t_l9r_go_relaxed.owl								dos	2017-03-21T16:06:48Z					biological_process											owl:Class	
GO:0070176	biolink:NamedThing	DRM complex	A transcriptional repressor complex that contains the lin-9, lin-35, lin-37, lin-52, lin-53, lin-5is involved in 4-, dpl-1 and efl-1 proteins, and is involved in cell fate specification.	tmpzr1t_l9r_go_relaxed.owl	DP/Rb/MuvB													cellular_component											owl:Class	
GO:0046499	biolink:NamedThing	S-adenosylmethioninamine metabolic process	The chemical reactions and pathways involving S-adenosylmethioninamine, (5-deoxy-5-adenosyl)(3-aminopropyl) methylsulfonium salt.	tmpzr1t_l9r_go_relaxed.owl	S-adenosylmethioninamine metabolism													biological_process											owl:Class	
GO:0098849	biolink:NamedThing	cellular detoxification of cadmium ion	Any process that reduces or removes the toxicity of cadmium cations in a cell. These include transport of cadmium cations away from sensitive areas and to compartments or complexes whose purpose is sequestration.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0050394	biolink:NamedThing	viomycin kinase activity	Catalysis of the reaction: ATP + viomycin = ADP + O-phosphoviomycin.	tmpzr1t_l9r_go_relaxed.owl	ATP:viomycin O-phosphotransferase activity|capreomycin phosphotransferase activity|viomycin phosphotransferase activity				MetaCyc:VIOMYCIN-KINASE-RXN|RHEA:20509|EC:2.7.1.103									molecular_function											owl:Class	
GO:0090470	biolink:NamedThing	shoot organ boundary specification	The process in which the basal boundary between the stem and both vegetative and reproductive organs are established and maintained.	tmpzr1t_l9r_go_relaxed.owl								tb	2012-09-24T16:22:03Z					biological_process											owl:Class	
GO:0090691	biolink:NamedThing	formation of plant organ boundary	The regionalization process that specifies plant organ primordium boundaries resulting in a restriction of organogenesis to a limited spatial domain and keeping the organ separate from surrounding tissues.	tmpzr1t_l9r_go_relaxed.owl								tb	2016-08-24T10:16:28Z					biological_process											owl:Class	
GO:0043737	biolink:NamedThing	deoxyribonuclease V activity	Catalysis of the endonucleolytic cleavage at apurinic or apyrimidinic sites to products with a 5'-phosphate.	tmpzr1t_l9r_go_relaxed.owl	endonuclease V activity|endodeoxyribonuclease V|Escherichia coli endodeoxyribonuclease V activity|DNase V activity				EC:3.1.21.7|MetaCyc:3.1.21.7-RXN									molecular_function											owl:Class	
GO:1990557	biolink:NamedThing	mitochondrial sulfate transmembrane transport	The process in which sulfate is transported across a mitochondrial membrane, into or out of the mitochondrion.	tmpzr1t_l9r_go_relaxed.owl								vw	2014-11-19T12:49:35Z					biological_process											owl:Class	
GO:2000038	biolink:NamedThing	regulation of stomatal complex development	Any process that modulates the frequency, rate or extent of stomatal complex development.	tmpzr1t_l9r_go_relaxed.owl								tb	2010-08-05T11:36:10Z					biological_process											owl:Class	
GO:0035177	biolink:NamedThing	larval foraging behavior	The movement of a larva through a feeding substrate whilst feeding on food.	tmpzr1t_l9r_go_relaxed.owl	larval foraging behaviour													biological_process											owl:Class	
GO:0030537	biolink:NamedThing	larval behavior	Behavior in a larval form of an organism, an immature organism that must undergo metamorphosis to assume adult characteristics.	tmpzr1t_l9r_go_relaxed.owl	larval behaviour					See also the biological process term 'behavior ; GO:0007610'.						GO:0017037		biological_process											owl:Class	
GO:0000411	biolink:NamedThing	positive regulation of transcription by galactose	Any process involving galactose that activates or increases the rate of transcription.	tmpzr1t_l9r_go_relaxed.owl	upregulation of transcription by galactose|up-regulation of transcription by galactose|stimulation of transcription by galactose|up regulation of transcription by galactose|activation of transcription by galactose													biological_process											owl:Class	
GO:0106347	biolink:NamedThing	U2 snRNA 2'-O-methyladenosine m6 methyltransferase activity	Catalysis of the reaction: a 2'-O-methyladenosine in U2 snRNA + S-adenosyl-L-methionine = an N6-methyl-2'-O-methyladenosine in U2 snRNA + S-adenosyl-L-homocysteine + H+.	tmpzr1t_l9r_go_relaxed.owl					RHEA:62672			hjd	2020-12-18T15:11:10Z					molecular_function											owl:Class	
GO:0043397	biolink:NamedThing	regulation of corticotropin-releasing hormone secretion	Any process that modulates the frequency, rate or extent of corticotropin-releasing hormone secretion.	tmpzr1t_l9r_go_relaxed.owl	regulation of CRF secretion|regulation of corticotropin-releasing factor secretion|regulation of CRH secretion													biological_process											owl:Class	
GO:0016039	biolink:NamedThing	absorption of UV light	The reception of a (UV light) photon by a cell, UV light being defined as having a wavelength within the range 13.6-400 nm.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0016037	biolink:NamedThing	light absorption	The reception of a photon by a cell.	tmpzr1t_l9r_go_relaxed.owl	absorption of light													biological_process											owl:Class	
GO:0075513	biolink:NamedThing	caveolin-mediated endocytosis of virus by host cell	Any caveolin-mediated endocytosis that is involved in the uptake of a virus into a host cell. Begins when material is taken up into plasma membrane caveolae - specialized lipid rafts that form 50-70 nm flask-shaped invaginations of the plasma membrane - which then pinch off to form endocytic caveolar carriers containing the virus.	tmpzr1t_l9r_go_relaxed.owl	viral penetration via caveolae-mediated endocytosis followed by endosome disruption|viral entry into host cell via caveolin-mediated endocytosis|viral entry into host cell via caveolae-mediated endocytosis				VZ:976			jl	2011-07-27T02:40:04Z					biological_process											owl:Class	
GO:0034182	biolink:NamedThing	regulation of maintenance of mitotic sister chromatid cohesion	Any process that modulates the extent to which the association between sister chromatids of a replicated chromosome is maintained during a mitotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0036413	biolink:NamedThing	histone H3-R26 citrullination	The hydrolysis of peptidyl-arginine to form peptidyl-citrulline at position 26 in histone H3.	tmpzr1t_l9r_go_relaxed.owl	histone H3 arginine 26 citrullination							bf	2013-08-22T13:59:15Z					biological_process											owl:Class	
GO:0036414	biolink:NamedThing	histone citrullination	The hydrolysis of peptidyl-arginine to form peptidyl-citrulline on a histone protein.	tmpzr1t_l9r_go_relaxed.owl	histone deimination							bf	2013-08-22T14:04:26Z					biological_process											owl:Class	
GO:1900000	biolink:NamedThing	regulation of anthocyanin catabolic process	Any process that modulates the frequency, rate or extent of anthocyanin catabolic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of anthocyanin catabolism|regulation of anthocyanin degradation|regulation of anthocyanin breakdown							tb	2011-12-20T07:12:07Z					biological_process											owl:Class	
GO:0034176	biolink:NamedThing	negative regulation of toll-like receptor 12 signaling pathway	Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 12 signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of toll-like receptor 12 signalling pathway|negative regulation of TLR12 signaling pathway													biological_process											owl:Class	
GO:1990067	biolink:NamedThing	intrachromosomal DNA recombination	The process of DNA recombination occurring within a single chromosome.	tmpzr1t_l9r_go_relaxed.owl	intrastrand DNA recombination							tb	2013-03-27T21:11:35Z					biological_process											owl:Class	
GO:0034740	biolink:NamedThing	TFIIIC-TOP1-SUB1 complex	A protein complex that contains TFIIIC, topoisomerase 1, and Sub1/PC4. Characterized in human, the complex is involved in regulating transcription from RNA polymerase III (Pol III) promoters. Topoisomerase 1 and Sub1 enhance the accuracy of transcription termination, and promote reinitiation by Pol III.	tmpzr1t_l9r_go_relaxed.owl	TFIIIC-Topoisomerase 1-PC4 complex													cellular_component											owl:Class	
GO:1901132	biolink:NamedThing	kanamycin catabolic process	The chemical reactions and pathways resulting in the breakdown of kanamycin.	tmpzr1t_l9r_go_relaxed.owl	kanamycin degradation|kanamycin catabolism|kanamycin breakdown							yaf	2012-07-11T03:27:24Z					biological_process											owl:Class	
GO:0090235	biolink:NamedThing	regulation of metaphase plate congression	Any process that modulates the rate, frequency, or extent of metaphase plate congression, the alignment of chromosomes at the metaphase plate, a plane halfway between the poles of the spindle.	tmpzr1t_l9r_go_relaxed.owl	regulation of chromosome congression							tb	2010-01-20T11:05:55Z					biological_process											owl:Class	
GO:1900880	biolink:NamedThing	18-methylnonadec-1-ene metabolic process	The chemical reactions and pathways involving 18-methylnonadec-1-ene.	tmpzr1t_l9r_go_relaxed.owl	18-methylnonadec-1-ene metabolism							tt	2012-06-13T02:26:28Z					biological_process											owl:Class	
GO:0075294	biolink:NamedThing	positive regulation by symbiont of entry into host	Any process that activates or increases the frequency, rate or extent to which it enters into the host organism, where the two organisms are in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	upregulation by organism of entry into other organism during symbiotic interaction|positive regulation by organism of entry into other organism involved in symbiotic interaction|activation by organism of entry into other organism during symbiotic interaction|up-regulation by organism of entry into other organism during symbiotic interaction|up-regulation by symbiont of entry into host|upregulation by symbiont of entry into host|up regulation by organism of entry into other organism during symbiotic interaction|activation by symbiont of entry into host|up regulation by symbiont of entry into host|positive regulation by organism of entry into other organism during symbiotic interaction	https://github.com/geneontology/go-ontology/issues/19027										GO:0075295		biological_process											owl:Class	
GO:0005105	biolink:NamedThing	type 1 fibroblast growth factor receptor binding	Binding to a type 1 fibroblast growth factor receptor (FGFR1).	tmpzr1t_l9r_go_relaxed.owl	FGFR1 binding|breathless ligand|type 1 fibroblast growth factor receptor ligand|FGFR1 ligand|breathless binding					Note that breathless is the Drosophila gene encoding the type 1 fibroblast growth factor receptor (FGFR1).								molecular_function											owl:Class	
GO:0005104	biolink:NamedThing	fibroblast growth factor receptor binding	Binding to a fibroblast growth factor receptor (FGFR).	tmpzr1t_l9r_go_relaxed.owl	fibroblast growth factor|FGFR binding|FGF receptor binding|FGFR ligand|fibroblast growth factor receptor ligand					Note that branchless is the Drosophila gene encoding fibroblast growth factor.						GO:0005162|GO:0001521		molecular_function											owl:Class	
GO:0015093	biolink:NamedThing	ferrous iron transmembrane transporter activity	Enables the transfer of ferrous iron (Fe(II) or Fe2+) ions from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	ferrous iron uptake transmembrane transporter activity				Reactome:R-HSA-1362417|RHEA:28486|Reactome:R-HSA-442368|Reactome:R-HSA-5655760							GO:0015639		molecular_function											owl:Class	
GO:1990839	biolink:NamedThing	response to endothelin	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an endothelin stimulus. Endothelin is any of three secretory vasoconstrictive peptides (endothelin-1, -2, -3).	tmpzr1t_l9r_go_relaxed.owl								sl	2015-08-27T19:37:52Z					biological_process											owl:Class	
GO:0033247	biolink:NamedThing	regulation of penicillin catabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of any antibiotic that contains the condensed beta-lactamthiazolidine ring system.	tmpzr1t_l9r_go_relaxed.owl	regulation of penicillin breakdown|regulation of penicillin degradation|regulation of penicillin catabolism													biological_process											owl:Class	
GO:0070982	biolink:NamedThing	L-asparagine metabolic process	The chemical reactions and pathways involving L-asparagine, (2S)-2-amino-3-carbamoylpropanoic acid.	tmpzr1t_l9r_go_relaxed.owl	L-asparagine metabolism							mah	2009-10-27T01:03:46Z					biological_process											owl:Class	
GO:0051655	biolink:NamedThing	maintenance of vesicle location	Any process in which a vesicle is maintained in a specific location within a cell and prevented from moving elsewhere.	tmpzr1t_l9r_go_relaxed.owl	maintenance of vesicle localization													biological_process											owl:Class	
GO:0047155	biolink:NamedThing	3-hydroxymethylcephem carbamoyltransferase activity	Catalysis of the reaction: a 3-hydroxymethylceph-3-em-4-carboxylate + carbamoyl-phosphate = phosphate + a 3-carbamoyloxymethylcephem.	tmpzr1t_l9r_go_relaxed.owl	carbamoyl-phosphate:3-hydroxymethylceph-3-em-4-carboxylate carbamoyltransferase activity|3'-hydroxymethylcephem-O-carbamoyltransferase activity				MetaCyc:2.1.3.7-RXN|EC:2.1.3.7							GO:0045447		molecular_function											owl:Class	
GO:1905814	biolink:NamedThing	positive regulation of motor neuron axon guidance	Any process that activates or increases the frequency, rate or extent of motor neuron axon guidance.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of motor axon pathfinding|up regulation of motor axon guidance|up-regulation of motoneuron axon guidance|upregulation of motor axon pathfinding|activation of motor axon guidance|activation of motor neuron axon guidance|positive regulation of motor axon pathfinding|up-regulation of motor axon guidance|positive regulation of motor axon guidance|upregulation of motor neuron axon guidance|up regulation of motor neuron axon guidance|upregulation of motoneuron axon guidance|up-regulation of motor neuron axon guidance|activation of motoneuron axon guidance|activation of motor axon pathfinding|up regulation of motoneuron axon guidance|up regulation of motor axon pathfinding|positive regulation of motoneuron axon guidance|upregulation of motor axon guidance							hbye	2017-01-12T13:25:31Z					biological_process											owl:Class	
GO:1905812	biolink:NamedThing	regulation of motor neuron axon guidance	Any process that modulates the frequency, rate or extent of motor neuron axon guidance.	tmpzr1t_l9r_go_relaxed.owl	regulation of motoneuron axon guidance|regulation of motor axon pathfinding|regulation of motor axon guidance							hbye	2017-01-12T13:25:12Z					biological_process											owl:Class	
GO:1903352	biolink:NamedThing	L-ornithine transmembrane transport	The directed movement of L-ornithine across a membrane.	tmpzr1t_l9r_go_relaxed.owl								pr	2014-08-20T13:01:38Z					biological_process											owl:Class	
GO:0021691	biolink:NamedThing	cerebellar Purkinje cell layer maturation	A developmental process, independent of morphogenetic (shape) change, that is required for the cerebellar Purkinje cell layer to attain its fully functional state. The Purkinje cell layer lies just underneath the molecular layer of the cerebellar cortex. It contains the neuronal cell bodies of the Purkinje cells that are arranged side by side in a single layer. Candelabrum interneurons are vertically oriented between the Purkinje cells. Purkinje neurons are inhibitory and provide the output of the cerebellar cortex through axons that project into the white matter. Extensive dendritic trees from the Purkinje cells extend upward in a single plane into the molecular layer where they synapse with parallel fibers of granule cells.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0060727	biolink:NamedThing	positive regulation of coreceptor activity involved in epidermal growth factor receptor signaling pathway	Any process that increases the rate or frequency of coreceptor activity involved in epidermal growth factor receptor signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of Neu/ErbB-2 receptor activity|positive regulation of coreceptor activity involved in epidermal growth factor receptor signalling pathway							dph	2009-06-12T01:30:50Z					biological_process											owl:Class	
GO:0005954	biolink:NamedThing	calcium- and calmodulin-dependent protein kinase complex	An enzyme complex which in eukaryotes is composed of four different chains: alpha, beta, gamma, and delta. The different isoforms assemble into homo- or heteromultimeric holoenzymes composed of 8 to 12 subunits. Catalyzes the phosphorylation of proteins to O-phosphoproteins.	tmpzr1t_l9r_go_relaxed.owl	CaMKII|calcium/calmodulin-dependent protein kinase complex|CAMK2													cellular_component											owl:Class	
GO:0010723	biolink:NamedThing	positive regulation of transcription from RNA polymerase II promoter in response to iron	Any process that increases the rate of transcription from an RNA polymerase II promoter in response to an iron stimulus.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1904553	biolink:NamedThing	negative regulation of chemotaxis to arachidonic acid	Any process that stops, prevents or reduces the frequency, rate or extent of chemotaxis to arachidonic acid.	tmpzr1t_l9r_go_relaxed.owl	downregulation of chemotaxis to arachidonic acid|down-regulation of chemotaxis to arachidonic acid|inhibition of chemotaxis to arachidonic acid|down regulation of chemotaxis to arachidonic acid							sl	2015-08-13T21:08:20Z					biological_process											owl:Class	
GO:0050906	biolink:NamedThing	detection of stimulus involved in sensory perception	The series of events involved in sensory perception in which a sensory stimulus is received and converted into a molecular signal.	tmpzr1t_l9r_go_relaxed.owl	sensory transduction|sensory detection of stimulus|sensory perception, sensory transduction of stimulus|sensory perception, stimulus detection				Wikipedia:Transduction_(physiology)									biological_process											owl:Class	
GO:1903597	biolink:NamedThing	negative regulation of gap junction assembly	Any process that stops, prevents or reduces the frequency, rate or extent of gap junction assembly.	tmpzr1t_l9r_go_relaxed.owl	downregulation of gap junction assembly|down-regulation of gap junction assembly|inhibition of gap junction assembly|down regulation of gap junction assembly							rl	2014-11-07T18:51:45Z					biological_process											owl:Class	
GO:0097441	biolink:NamedThing	basal dendrite	A dendrite that emerges near the basal pole of a neuron. In bipolar neurons, basal dendrites are either on the same side of the soma as the axon, or project toward the axon.	tmpzr1t_l9r_go_relaxed.owl	basilar dendrite				NIF_Subcellular:sao1079900774			pr	2012-12-06T13:46:28Z					cellular_component											owl:Class	
GO:1904679	biolink:NamedThing	myo-inositol import across plasma membrane	The directed movement of myo-inositol from outside of a cell, across the plasma membrane and into the cytosol.	tmpzr1t_l9r_go_relaxed.owl	myo-inositol import into cell							al	2012-07-03T06:22:05Z			GO:0097357		biological_process											owl:Class	
GO:0045808	biolink:NamedThing	negative regulation of establishment of competence for transformation	Any process that stops, prevents, or reduces the frequency, rate or extent of establishment of competence for transformation.	tmpzr1t_l9r_go_relaxed.owl	inhibitor of the establishment of competence for transformation activity|down-regulation of establishment of competence for transformation|inhibition of establishment of competence for transformation|down regulation of establishment of competence for transformation|downregulation of establishment of competence for transformation													biological_process											owl:Class	
GO:0002874	biolink:NamedThing	regulation of chronic inflammatory response to antigenic stimulus	Any process that modulates the frequency, rate, or extent of a chronic inflammatory response to an antigenic stimulus.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0043958	biolink:NamedThing	acryloyl-CoA reductase activity	Catalysis of the reaction: acryloyl-CoA + NADH + H+ + a reduced electron-transfer flavoprotein = propionyl-CoA + NAD+ + an oxidized electron-transfer flavoprotein.	tmpzr1t_l9r_go_relaxed.owl	acryloyl-coenzyme A reductase activity|acrylyl-CoA reductase (NADH)|propionyl-CoA dehydrogenase				EC:1.3.99.3|RHEA:34471|MetaCyc:RXN-8568	Note that this function is part of the process of L-alanine fermentation to propionate.								molecular_function											owl:Class	
GO:0034893	biolink:NamedThing	N-nitrodimethylamine hydroxylase activity	Catalysis of the reaction: N-nitrodimethylamine + O2 + 2 H+ + 2 e- = N-nitromethylamine + formaldehyde + H2O.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r1395									molecular_function											owl:Class	
GO:1902643	biolink:NamedThing	positive regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process	Any process that activates or increases the frequency, rate or extent of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate degradation|up regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate degradation|upregulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolism|positive regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate breakdown|up regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate breakdown|activation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate degradation|activation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolism|up-regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process|up regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process|positive regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate degradation|up regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolism|upregulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate breakdown|activation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process|up-regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolism|upregulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate degradation|activation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate breakdown|upregulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process|positive regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolism|up-regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate breakdown							di	2014-01-21T17:54:32Z					biological_process											owl:Class	
GO:1903407	biolink:NamedThing	negative regulation of P-type sodium:potassium-exchanging transporter activity	Any process that stops, prevents or reduces the frequency, rate or extent of sodium:potassium-exchanging ATPase activity.	tmpzr1t_l9r_go_relaxed.owl	downregulation of Na(+)/K(+)-ATPase activity|negative regulation of Na+,K+ pump|down regulation of Na,K-pump|down regulation of sodium:potassium exchanging ATPase activity|negative regulation of (Na+ + K+)-ATPase activity|down regulation of Na+/K+-exchanging ATPase activity|down regulation of Na+/K+-ATPase activity|inhibition of Na,K-pump|down-regulation of (Na+ + K+)-ATPase activity|downregulation of Na,K-pump|down regulation of sodium:potassium-exchanging ATPase activity|downregulation of ATP phosphohydrolase (Na+/K+-exchanging)|down-regulation of Na+,K+-ATPase activity|inhibition of sodium:potassium-exchanging ATPase activity|downregulation of sodium/potassium-transporting ATPase activity|down-regulation of Na+/K+-exchanging ATPase activity|down regulation of Na+,K+ pump|downregulation of Na+/K+-ATPase activity|downregulation of sodium/potassium-exchanging ATPase activity|inhibition of Na+,K+ pump|down-regulation of sodium:potassium-exchanging ATPase activity|downregulation of (Na+ + K+)-activated ATPase activity|downregulation of (Na+ + K+)-ATPase activity|down regulation of Na(+)/K(+)-exchanging ATPase activity|inhibition of Na(+)/K(+)-exchanging ATPase activity|down regulation of sodium/potassium-transporting ATPase activity|down-regulation of sodium:potassium exchanging ATPase activity|downregulation of sodium:potassium-exchanging ATPase activity|inhibition of Na,K-activated ATPase activity|negative regulation of Na,K-activated ATPase activity|down regulation of Na,K-activated ATPase activity|inhibition of Na+/K+-ATPase activity|down-regulation of sodium/potassium-transporting ATPase activity|down-regulation of Na+,K+ pump|down regulation of sodium/potassium-exchanging ATPase activity|negative regulation of (Na+ + K+)-activated ATPase activity|negative regulation of sodium:potassium-exchanging ATPase activity|down-regulation of Na,K-activated ATPase activity|downregulation of Na+,K+ pump|negative regulation of sodium/potassium-transporting ATPase activity|down regulation of ATP phosphohydrolase (Na+/K+-exchanging)|downregulation of Na,K-activated ATPase activity|negative regulation of Na(+)/K(+)-ATPase activity|inhibition of (Na+ + K+)-activated ATPase activity|down-regulation of Na+/K+-ATPase activity|inhibition of Na+/K+-exchanging ATPase activity|inhibition of Na+,K+-ATPase activity|negative regulation of Na+,K+-ATPase activity|negative regulation of sodium/potassium-exchanging ATPase activity|negative regulation of Na(+)/K(+)-exchanging ATPase activity|inhibition of ATP phosphohydrolase (Na+/K+-exchanging)|inhibition of sodium/potassium-exchanging ATPase activity|down-regulation of ATP phosphohydrolase (Na+/K+-exchanging)|down regulation of Na+,K+-ATPase activity|inhibition of (Na+ + K+)-ATPase activity|negative regulation of Na,K-pump|downregulation of Na(+)/K(+)-exchanging ATPase activity|inhibition of Na(+)/K(+)-ATPase activity|downregulation of sodium:potassium exchanging ATPase activity|down-regulation of sodium/potassium-exchanging ATPase activity|down regulation of (Na+ + K+)-activated ATPase activity|down regulation of Na(+)/K(+)-ATPase activity|down-regulation of Na,K-pump|downregulation of Na+/K+-exchanging ATPase activity|down-regulation of Na(+)/K(+)-exchanging ATPase activity|down-regulation of (Na+ + K+)-activated ATPase activity|downregulation of Na+,K+-ATPase activity|down regulation of (Na+ + K+)-ATPase activity|negative regulation of Na+/K+-exchanging ATPase activity|negative regulation of Na+/K+-ATPase activity|down-regulation of Na(+)/K(+)-ATPase activity|inhibition of sodium/potassium-transporting ATPase activity|inhibition of sodium:potassium exchanging ATPase activity|negative regulation of sodium:potassium exchanging ATPase activity|negative regulation of ATP phosphohydrolase (Na+/K+-exchanging)							mr	2014-09-02T19:45:16Z					biological_process											owl:Class	
GO:1903406	biolink:NamedThing	regulation of P-type sodium:potassium-exchanging transporter activity	Any process that modulates the frequency, rate or extent of sodium:potassium-exchanging ATPase activity.	tmpzr1t_l9r_go_relaxed.owl	regulation of Na(+)/K(+)-exchanging ATPase activity|regulation of sodium/potassium-exchanging ATPase activity|regulation of sodium/potassium-transporting ATPase activity|regulation of ATP phosphohydrolase (Na+/K+-exchanging)|regulation of sodium:potassium exchanging ATPase activity|regulation of Na+/K+-ATPase activity|regulation of sodium pump|regulation of (Na+ + K+)-activated ATPase activity|regulation of Na,K-activated ATPase activity|regulation of Na,K-pump|regulation of sodium:potassium-exchanging ATPase activity|regulation of Na+,K+-ATPase activity|regulation of (Na+ + K+)-ATPase activity|regulation of Na+,K+ pump|regulation of Na(+)/K(+)-ATPase activity|regulation of Na+/K+-exchanging ATPase activity							mr	2014-09-02T19:45:08Z					biological_process											owl:Class	
GO:0061722	biolink:NamedThing	sulphoglycolysis	The chemical reactions and pathways resulting in the breakdown of 6-sulfoquinovose(1-) resulting in the formation of glycerone phosphate (DHAP) and pyruvate.	tmpzr1t_l9r_go_relaxed.owl	sulfoglycolysis							dph	2015-07-01T09:44:30Z					biological_process											owl:Class	
GO:0102893	biolink:NamedThing	betanidin 6-O-glucosyltransferase activity	Catalysis of the reaction: UDP-alpha-D-glucose + betanidin <=> H+ + gomphrenin I + UDP.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-8480									molecular_function											owl:Class	
GO:2000717	biolink:NamedThing	positive regulation of maintenance of mitotic sister chromatid cohesion, arms	Any process that activates or increases the frequency, rate or extent of maintenance of mitotic sister chromatid cohesion along the chromosome arms.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of maintenance of mitotic sister chromatin cohesion along arms|positive regulation of maintenance of sister chromatin cohesion along arms at mitosis							mah	2011-06-03T10:38:35Z					biological_process											owl:Class	
GO:0019558	biolink:NamedThing	histidine catabolic process to 2-oxoglutarate	The chemical reactions and pathways resulting in the breakdown of histidine into other compounds, including 2-oxoglutarate.	tmpzr1t_l9r_go_relaxed.owl	histidine catabolism to alpha-oxoglutarate|histidine degradation to 2-oxoglutarate|histidine catabolism to 2-ketoglutarate|histidine catabolic process to 2-ketoglutarate|histidine catabolism to alpha-ketoglutarate|histidine catabolic process to alpha-oxoglutarate|histidine breakdown to 2-oxoglutarate|histidine catabolic process to alpha-ketoglutarate													biological_process											owl:Class	
GO:0048782	biolink:NamedThing	negative regulation of cyanophore differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of cyanophore differentiation.	tmpzr1t_l9r_go_relaxed.owl	downregulation of cyanophore differentiation|inhibition of cyanophore differentiation|down regulation of cyanophore differentiation|down-regulation of cyanophore differentiation													biological_process											owl:Class	
GO:0051066	biolink:NamedThing	dihydrobiopterin metabolic process	The chemical reactions and pathways involving a dihydrobiopterin, a reduced pteridine derivative related to folic acid; it acts as an electron carrier in tyrosine biosynthesis and its quinoid form is produced by oxidation of tetrahydrobiopterin in several biological hydroxylation reactions.	tmpzr1t_l9r_go_relaxed.owl	dihydropterin metabolic process|dihydropterin metabolism|6,7-dihydrobiopterin metabolic process|dihydrobiopterin reduction|7,8-dihydrobiopterin metabolic process													biological_process											owl:Class	
GO:1905589	biolink:NamedThing	positive regulation of L-arginine import across plasma membrane	Any process that activates or increases the frequency, rate or extent of L-arginine import across plasma membrane.	tmpzr1t_l9r_go_relaxed.owl	upregulation of L-arginine import|up-regulation of L-arginine import|upregulation of L-arginine import into cell|activation of L-arginine import across plasma membrane|up-regulation of L-arginine uptake|activation of L-arginine uptake|positive regulation of L-arginine uptake|positive regulation of L-arginine import into cell|activation of L-arginine import into cell|upregulation of L-arginine uptake|up regulation of L-arginine uptake|up regulation of L-arginine import|positive regulation of L-arginine import|up-regulation of L-arginine import into cell|activation of L-arginine import							al	2012-06-25T12:27:24Z			GO:1901042|GO:1902828		biological_process											owl:Class	
GO:0071013	biolink:NamedThing	catalytic step 2 spliceosome	A spliceosomal complex that contains three snRNPs, including U5, bound to a splicing intermediate in which the first catalytic cleavage of the 5' splice site has occurred. The precise subunit composition differs significantly from that of the catalytic step 1, or activated, spliceosome, and includes many proteins in addition to those found in the associated snRNPs.	tmpzr1t_l9r_go_relaxed.owl	mammalian spliceosomal complex C1|mammalian spliceosomal complex C|yeast spliceosomal complex A2-2							mah	2009-07-30T12:00:35Z					cellular_component											owl:Class	
GO:0031829	biolink:NamedThing	type 4 serotonin receptor binding	Binding to a type 4 serotonin receptor.	tmpzr1t_l9r_go_relaxed.owl	5-hydroxytryptamine 4 receptor binding|type 4 serotonin receptor ligand													molecular_function											owl:Class	
GO:0075514	biolink:NamedThing	endosome lysis involved in viral entry into host cell	Viral-induced lysis of the endosome involved in uptake of a virus into a host cell. Occurs after internalization of the virus through the endosomal pathway, and results in release of the viral contents from the endosome into the host cell cytoplasm.	tmpzr1t_l9r_go_relaxed.owl	viral entry into host cell via caveolae-mediated endocytosis followed by endosome lysis							jl	2011-07-27T02:56:15Z					biological_process											owl:Class	
GO:0035476	biolink:NamedThing	angioblast cell migration	The orderly movement of angioblasts, cells involved in blood vessel morphogenesis.	tmpzr1t_l9r_go_relaxed.owl								bf	2010-04-23T10:06:32Z					biological_process											owl:Class	
GO:0036187	biolink:NamedThing	cell growth mode switching, budding to filamentous	The process in which a cell switches from growing as a round budding cell to growing as a filament (elongated cells attached end-to-end). An example of this is the yeast-hyphal transition of Candida albicans.	tmpzr1t_l9r_go_relaxed.owl	yeast to hyphal transition							bf	2012-04-18T11:32:57Z					biological_process											owl:Class	
GO:0006450	biolink:NamedThing	regulation of translational fidelity	Any process that modulates the ability of the translational apparatus to interpret the genetic code.	tmpzr1t_l9r_go_relaxed.owl	regulation of translational accuracy											GO:0000029		biological_process											owl:Class	
GO:0005249	biolink:NamedThing	voltage-gated potassium channel activity	Enables the transmembrane transfer of a potassium ion by a voltage-gated channel. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.	tmpzr1t_l9r_go_relaxed.owl	voltage-dependent potassium channel activity|voltage-gated potassium ion channel activity|voltage-sensitive potassium channel|voltage gated potassium channel activity				Reactome:R-HSA-1296127									molecular_function											owl:Class	
GO:2000783	biolink:NamedThing	negative regulation of establishment of cell polarity regulating cell shape	Any process that stops, prevents or reduces the frequency, rate or extent of establishment of cell polarity regulating cell shape.	tmpzr1t_l9r_go_relaxed.owl								mah	2011-06-23T12:17:44Z					biological_process											owl:Class	
GO:0015398	biolink:NamedThing	high-affinity secondary active ammonium transmembrane transporter activity	Enables the transfer of ammonium from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.	tmpzr1t_l9r_go_relaxed.owl	high affinity secondary active ammonium transmembrane transporter activity													molecular_function											owl:Class	
GO:0032405	biolink:NamedThing	MutLalpha complex binding	Binding to a MutLalpha mismatch repair complex.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0150008	biolink:NamedThing	bulk synaptic vesicle endocytosis	Endocytosis of large regions of presynaptic membrane after intense stimulation-mediated fusion of multiple synaptic vesicles. Bulk endocytosis is triggered by high loads of membrane addition through exocytosis of synaptic vesicles and elevated concentration of calcium in the presynapse.	tmpzr1t_l9r_go_relaxed.owl	bulk endocytosis|activity-dependent bulk endocytosis|activity-dependent bulk synaptic vesicle endocytosis|ADBE							bc	2017-12-01T10:20:18Z					biological_process											owl:Class	
GO:0051517	biolink:NamedThing	negative regulation of bipolar cell growth	Any process that stops, prevents, or reduces the frequency, rate or extent of bipolar cell growth, polarized growth from both ends of a cell.	tmpzr1t_l9r_go_relaxed.owl	inhibition of bipolar cell growth|down regulation of bipolar cell growth|downregulation of bipolar cell growth|down-regulation of bipolar cell growth													biological_process											owl:Class	
GO:0097145	biolink:NamedThing	BAK complex	An oligomeric protein complex consisting of BAK, a member of the Bcl-2 family of anti- and proapoptotic regulators.	tmpzr1t_l9r_go_relaxed.owl								pr	2011-08-02T01:48:11Z					cellular_component											owl:Class	
GO:0050669	biolink:NamedThing	negative regulation of homocysteine metabolic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving homocysteine.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of Hcy metabolism|down regulation of homocysteine metabolic process|down-regulation of homocysteine metabolic process|negative regulation of homocysteine metabolism|downregulation of homocysteine metabolic process|inhibition of homocysteine metabolic process|negative regulation of Hcy metabolic process													biological_process											owl:Class	
GO:0042540	biolink:NamedThing	hemoglobin catabolic process	The chemical reactions and pathways resulting in the breakdown of hemoglobin, an oxygen carrying, conjugated protein containing four heme groups and globin; especially, the proteolytic cleavage of hemoglobin to yield free heme, peptides, and amino acids.	tmpzr1t_l9r_go_relaxed.owl	hemoglobin hydrolysis|hemoglobin breakdown|hemoglobin degradation|haemoglobin hydrolysis|haemoglobin catabolic process|hemoglobin catabolism|haemoglobin catabolism					Note that 'hydrolysis' is actually a reaction rather than a process. The synonym 'hemoglobin hydrolysis' was the text string associated with the secondary ID GO:0020029, which was retained because its definition did describe a process.						GO:0020029		biological_process											owl:Class	
GO:0052079	biolink:NamedThing	induction by symbiont of defense-related host MAP kinase-mediated signal transduction pathway	Any process in which an organism activates, maintains or increases the frequency, rate or extent of a host MAP kinase-mediated signal transduction pathway during the host innate immune response. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	positive regulation by organism of defense-related host MAPK-mediated signal transduction pathway|upregulation by symbiont of defense-related host MAP kinase-mediated signal transduction pathway|up-regulation by symbiont of defense-related host MAP kinase-mediated signal transduction pathway|up regulation by symbiont of defense-related host MAP kinase-mediated signal transduction pathway|upregulation by organism of defense-related host MAP kinase-mediated signal transduction pathway|induction by organism of defense-related host MAP kinase-mediated signal transduction pathway|positive regulation by symbiont of defense-related host MAP kinase-mediated signal transduction pathway|positive regulation by organism of defense-related host mitogen-activated protein kinase-mediated signal transduction pathway|activation by symbiont of defense-related host MAP kinase-mediated signal transduction pathway|activation by organism of defense-related host MAP kinase-mediated signal transduction pathway|positive regulation by organism of defense-related MAP kinase-mediated signal transduction pathway in other organism involved in symbiotic interaction|stimulation by symbiont of defense-related host MAP kinase-mediated signal transduction pathway	https://github.com/geneontology/go-ontology/issues/19235										GO:0052276		biological_process											owl:Class	
GO:0015097	biolink:NamedThing	mercury ion transmembrane transporter activity	Enables the transfer of mercury (Hg) ions from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl					RHEA:32815									molecular_function											owl:Class	
GO:1904142	biolink:NamedThing	negative regulation of carotenoid biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of carotenoid biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	down regulation of carotenoid biosynthetic process|down-regulation of carotenoid biosynthesis|down regulation of carotenoid biosynthesis|inhibition of carotenoid synthesis|down regulation of carotenoid synthesis|downregulation of carotenoid anabolism|inhibition of carotenoid anabolism|negative regulation of carotenoid formation|down-regulation of carotenoid synthesis|down regulation of carotenoid anabolism|inhibition of carotenoid formation|negative regulation of carotenoid biosynthesis|negative regulation of carotenoid anabolism|downregulation of carotenoid formation|downregulation of carotenoid synthesis|downregulation of carotenoid biosynthesis|inhibition of carotenoid biosynthesis|downregulation of carotenoid biosynthetic process|inhibition of carotenoid biosynthetic process|down regulation of carotenoid formation|down-regulation of carotenoid formation|down-regulation of carotenoid anabolism|negative regulation of carotenoid synthesis|down-regulation of carotenoid biosynthetic process							tb	2015-04-13T19:39:13Z					biological_process											owl:Class	
GO:0042826	biolink:NamedThing	histone deacetylase binding	Binding to histone deacetylase.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0018909	biolink:NamedThing	dodecyl sulfate metabolic process	The chemical reactions and pathways involving dodecyl sulfate, commonly found as sodium dodecyl sulfate (SDS), a component of a variety of synthetic surfactants.	tmpzr1t_l9r_go_relaxed.owl	dodecyl sulphate metabolic process|dodecyl sulfate metabolism|dodecyl sulphate metabolism				UM-BBD_pathwayID:dds									biological_process											owl:Class	
GO:0050460	biolink:NamedThing	hydroxylamine reductase (NADH) activity	Catalysis of the reaction: NH3 + NAD+ + H2O = hydroxylamine + NADH + H+.	tmpzr1t_l9r_go_relaxed.owl	ammonium:NAD+ oxidoreductase activity|N-hydroxy amine reductase activity|NADH:hydroxylamine oxidoreductase activity|ammonium dehydrogenase activity|NADH-hydroxylamine reductase activity|hydroxylamine reductase (NADH2)|NADH2:hydroxylamine oxidoreductase activity				MetaCyc:HYDROXYLAMINE-REDUCTASE-NADH-RXN|RHEA:20581|EC:1.7.1.10									molecular_function											owl:Class	
GO:0097278	biolink:NamedThing	complement-dependent cytotoxicity	Cell killing caused by the membrane attack complex formed following complement activation.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/18715						pr	2012-03-22T05:04:04Z					biological_process											owl:Class	
GO:0098952	biolink:NamedThing	intrinsic component of spine apparatus membrane	The component of the spine apparatus membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.	tmpzr1t_l9r_go_relaxed.owl	intrinsic to spine apparatus membrane													cellular_component											owl:Class	
GO:0047304	biolink:NamedThing	2-aminoethylphosphonate-pyruvate transaminase activity	Catalysis of the reaction: (2-aminoethyl)phosphonate + pyruvate = L-alanine + phosphonoacetaldehyde.	tmpzr1t_l9r_go_relaxed.owl	2-aminoethylphosphonate aminotransferase activity|2-aminoethylphosphonate-pyruvate aminotransferase activity|(2-aminoethyl)phosphonate aminotransferase activity|(2-aminoethyl)phosphonic acid aminotransferase activity|(2-aminoethyl)phosphonate transaminase activity|(2-aminoethyl)phosphonate:pyruvate aminotransferase activity|2-aminoethylphosphonate--pyruvate aminotransferase activity|(2-aminoethyl)phosphonate--pyruvate aminotransferase activity				EC:2.6.1.37|KEGG_REACTION:R04152|RHEA:17021|MetaCyc:2.6.1.37-RXN									molecular_function											owl:Class	
GO:1904180	biolink:NamedThing	negative regulation of membrane depolarization	Any process that stops, prevents or reduces the frequency, rate or extent of membrane depolarization.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of membrane depolarization|downregulation of membrane depolarization|down regulation of membrane depolarization|inhibition of membrane depolarization							sl	2015-04-29T22:29:25Z					biological_process											owl:Class	
GO:0102831	biolink:NamedThing	stachyose synthase activity	Catalysis of the reaction: 2 raffinose <=> stachyose + sucrose.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-8287									molecular_function											owl:Class	
GO:0070118	biolink:NamedThing	organellar chromatophore thylakoid membrane	The lipid bilayer membrane of any thylakoid within an organellar chromatophore.	tmpzr1t_l9r_go_relaxed.owl	Paulinella-type chromatophore thylakoid membrane													cellular_component											owl:Class	
GO:0035006	biolink:NamedThing	melanization defense response	The blackening of the wounded area of the cuticle or the surface of invading pathogens, parasites or parasitoids, resulting from a proteolytic cascade leading to the de novo synthesis and deposition of melanin.	tmpzr1t_l9r_go_relaxed.owl	melanization defence response													biological_process											owl:Class	
GO:2000228	biolink:NamedThing	positive regulation of pancreatic A cell differentiation	Any process that activates or increases the frequency, rate or extent of pancreatic A cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of pancreatic alpha cell differentiation							mah	2010-11-09T03:43:42Z					biological_process											owl:Class	
GO:0032966	biolink:NamedThing	negative regulation of collagen biosynthetic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of collagen synthesis|negative regulation of collagen biosynthesis|negative regulation of collagen anabolism|negative regulation of collagen formation													biological_process											owl:Class	
GO:0047005	biolink:NamedThing	16-alpha-hydroxysteroid dehydrogenase activity	Catalysis of the reaction: NADP+ + 16-alpha-hydroxysteroid = NADPH + H+ + 16-oxosteroid.	tmpzr1t_l9r_go_relaxed.owl	16alpha-hydroxysteroid dehydrogenase activity|16alpha-hydroxy steroid dehydrogenase activity|16alpha-hydroxysteroid:NAD(P)+ 16-oxidoreductase activity				MetaCyc:1.1.1.147-RXN|EC:1.1.1.147									molecular_function											owl:Class	
GO:0047979	biolink:NamedThing	hexose oxidase activity	Catalysis of the reaction: hexose + O2 = aldono-1,5-lactone + H202.	tmpzr1t_l9r_go_relaxed.owl	D-hexose:oxygen 1-oxidoreductase activity				EC:1.1.3.5|MetaCyc:HEXOSE-OXIDASE-RXN									molecular_function											owl:Class	
GO:0051930	biolink:NamedThing	regulation of sensory perception of pain	Any process that modulates the frequency, rate or extent of the sensory perception of pain, the series of events required for an organism to receive a painful stimulus, convert it to a molecular signal, and recognize and characterize the signal.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0034135	biolink:NamedThing	regulation of toll-like receptor 2 signaling pathway	Any process that modulates the frequency, rate, or extent of toll-like receptor 2 signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	regulation of toll-like receptor 2 signalling pathway|regulation of TLR2 signaling pathway													biological_process											owl:Class	
GO:0090071	biolink:NamedThing	negative regulation of ribosome biogenesis	Any process that decreases the rate, frequency or extent of ribosome biogenesis. Ribosome biogenesis is the cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-09-11T10:32:17Z					biological_process											owl:Class	
GO:0047000	biolink:NamedThing	2-dehydro-3-deoxy-D-gluconate 6-dehydrogenase activity	Catalysis of the reaction: 2-dehydro-3-deoxy-D-gluconate + NADP(+) = (4S,5S)-4,5-dihydroxy-2,6-dioxohexanoate + H(+) + NADPH.	tmpzr1t_l9r_go_relaxed.owl	2-dehydro-3-deoxy-D-gluconate:NADP+ 6-oxidoreductase activity|2-keto-3-deoxy-D-gluconate dehydrogenase activity				EC:1.1.1.126|MetaCyc:1.1.1.126-RXN|RHEA:15109|KEGG_REACTION:R01543									molecular_function											owl:Class	
GO:0009829	biolink:NamedThing	cell wall modification involved in fruit ripening	The series of events resulting in chemical or structural alterations of existing cell walls that contribute to fruit ripening.	tmpzr1t_l9r_go_relaxed.owl	cell wall modification during ripening													biological_process											owl:Class	
GO:0009433	biolink:NamedThing	bacterial-type flagellum basal body, C ring	Cytoplasmic ring located at the base of the bacterial-type flagellar basal body; acts as a rotor; includes three switch proteins, which generate torque and can change their conformational state in a bimodal fashion, so that the motor direction can switch between clockwise and counterclockwise.	tmpzr1t_l9r_go_relaxed.owl	flagellar basal body, C ring|flagellin-based flagellum basal body, C ring													cellular_component											owl:Class	
GO:0018976	biolink:NamedThing	1,2,3-tribromopropane metabolic process	The chemical reactions and pathways involving 1,2,3-tribromopropane, a toxic and volatile organic compound commonly used as a nematocide in agriculture.	tmpzr1t_l9r_go_relaxed.owl	1,2,3-tribromopropane metabolism				UM-BBD_pathwayID:tbp									biological_process											owl:Class	
GO:0006179	biolink:NamedThing	guanosine salvage	Any process that generates guanosine, guanine riboside, from derivatives of it without de novo synthesis.	tmpzr1t_l9r_go_relaxed.owl	guanine, xanthine and their nucleoside salvage													biological_process											owl:Class	
GO:0046114	biolink:NamedThing	guanosine biosynthetic process	The chemical reactions and pathways resulting in the formation of guanine, guanine riboside, a nucleoside with a wide species distribution.	tmpzr1t_l9r_go_relaxed.owl	guanosine biosynthesis|guanosine synthesis|guanosine formation|guanosine anabolism													biological_process											owl:Class	
GO:1902670	biolink:NamedThing	carbon dioxide binding	Binding to carbon dioxide.	tmpzr1t_l9r_go_relaxed.owl	CO2 binding							bhm	2014-02-04T10:38:41Z					molecular_function											owl:Class	
GO:0043644	biolink:NamedThing	tetracycline biosynthetic process	The chemical reactions and pathways resulting in the formation of tetracycline, (4S,4aS,5aS,6S,12aS)-4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide, a broad-spectrum antibiotic produced by streptomyces bacteria that blocks binding of aminoacyl tRNA to the ribosomes of both Gram-positive and Gram-negative organisms (and those of organelles).	tmpzr1t_l9r_go_relaxed.owl	tetracyclin biosynthetic process|tetracyclin biosynthesis													biological_process											owl:Class	
GO:0048506	biolink:NamedThing	regulation of timing of meristematic phase transition	Any process that modulates the rate, frequency or extent of a change in identity of a meristem at a characteristic predetermined time point.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0032677	biolink:NamedThing	regulation of interleukin-8 production	Any process that modulates the frequency, rate, or extent of interleukin-8 production.	tmpzr1t_l9r_go_relaxed.owl	regulation of IL-8 production|regulation of interleukin-8 secretion|regulation of interleukin-8 biosynthetic process											GO:2000482|GO:0045414		biological_process											owl:Class	
GO:0021792	biolink:NamedThing	chemoattraction of branchiomotor axon	The process in which a branchiomotor neuron growth cone is directed to a specific target site in response to an attractive chemical signal. Branchiomotor neurons are located in the hindbrain and innervate branchial arch-derived muscles that control jaw movements, facial expression, the larynx, and the pharynx.	tmpzr1t_l9r_go_relaxed.owl	positive chemotaxis of branchiomotor axon													biological_process											owl:Class	
GO:0001827	biolink:NamedThing	inner cell mass cell fate commitment	The cell fate commitment of precursor cells that will become inner cell mass cells.	tmpzr1t_l9r_go_relaxed.owl						See also the Anatomical Dictionary for Mouse Development ontology terms 'TS4, compacted morula ; EMAP:13' and 'TS4, inner cell mass ; EMAP:14'.								biological_process											owl:Class	
GO:0005537	biolink:NamedThing	mannose binding	Binding to mannose, a monosaccharide hexose, stereoisomeric with glucose, that occurs naturally only in polymerized forms called mannans.	tmpzr1t_l9r_go_relaxed.owl	mannose binding lectin				Reactome:R-HSA-947991									molecular_function											owl:Class	
GO:0016234	biolink:NamedThing	inclusion body	A discrete intracellular part formed of aggregated molecules such as proteins or other biopolymers.	tmpzr1t_l9r_go_relaxed.owl	cellular inclusion|neuronal cytoplasmic inclusion				Wikipedia:Inclusion_bodies|NIF_Subcellular:sao120573470									cellular_component											owl:Class	
GO:2000649	biolink:NamedThing	regulation of sodium ion transmembrane transporter activity	Any process that modulates the frequency, rate or extent of sodium ion transmembrane transporter activity.	tmpzr1t_l9r_go_relaxed.owl	regulation of sodium transporter activity							yaf	2011-04-28T08:42:53Z					biological_process											owl:Class	
GO:0098777	biolink:NamedThing	protein secretion by the type VIII secretion system	Protein secretion through the outer membrane via the mechanism used for the secretion of curli subunits.	tmpzr1t_l9r_go_relaxed.owl	T8SS					This term is defined so as to leave open the possibility that things other than curli subunits are secreted via same secretory system as that used by curli subunits.								biological_process											owl:Class	
GO:0072575	biolink:NamedThing	epithelial cell proliferation involved in liver morphogenesis	The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population that contributes to the shaping of the liver.	tmpzr1t_l9r_go_relaxed.owl								mah	2011-02-02T03:37:50Z					biological_process											owl:Class	
GO:0010887	biolink:NamedThing	negative regulation of cholesterol storage	Any process that decreases the rate or extent of cholesterol storage. Cholesterol storage is the accumulation and maintenance in cells or tissues of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of cholesterol sequestration													biological_process											owl:Class	
GO:0050083	biolink:NamedThing	malyl-CoA lyase activity	Catalysis of the reaction: (3S)-3-carboxy-3-hydroxypropanoyl-CoA = acetyl-CoA + glyoxylate.	tmpzr1t_l9r_go_relaxed.owl	malyl-coenzyme A lyase activity|(3S)-3-carboxy-3-hydroxypropanoyl-CoA glyoxylate-lyase activity|(3S)-3-carboxy-3-hydroxypropanoyl-CoA glyoxylate-lyase (acetyl-CoA-forming)				MetaCyc:MALYL-COA-LYASE-RXN|EC:4.1.3.24|RHEA:16629									molecular_function											owl:Class	
GO:0060644	biolink:NamedThing	mammary gland epithelial cell differentiation	The process in which a relatively unspecialized epithelial cell becomes a more specialized epithelial cell of the mammary gland.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-05-29T08:03:07Z					biological_process											owl:Class	
GO:0051574	biolink:NamedThing	positive regulation of histone H3-K9 methylation	Any process that activates or increases the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 9 of histone H3.	tmpzr1t_l9r_go_relaxed.owl	up regulation of histone H3-K9 methylation|stimulation of histone H3-K9 methylation|upregulation of histone H3-K9 methylation|up-regulation of histone H3-K9 methylation|activation of histone H3-K9 methylation													biological_process											owl:Class	
GO:0000449	biolink:NamedThing	endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 5S)	Endonucleolytic cleavage of a pre-rRNA molecule originally produced as a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, the Large Subunit (LSU) rRNA, and the 5S rRNA, in that order, from 5' to 3' along the primary transcript. For example, primary ribosomal RNA transcripts containing three genes, in this order, are produced in E. coli and other prokaryotic species. Note that the use of the word tricistronic refers only to the number of mature rRNA molecules which will be produced from the primary transcript and ignores tRNAs that may also be present within the primary transcript.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1903131	biolink:NamedThing	mononuclear cell differentiation	The process in which a relatively unspecialized cell acquires the specialized features of a mononuclear cell.	tmpzr1t_l9r_go_relaxed.owl								cls	2014-06-25T15:47:09Z					biological_process											owl:Class	
GO:0016728	biolink:NamedThing	oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which a CH2 group acts as a hydrogen or electron donor and reduces a disulfide group.	tmpzr1t_l9r_go_relaxed.owl	oxidoreductase activity, acting on CH or CH2 groups, disulphide as acceptor				EC:1.17.4.-									molecular_function											owl:Class	
GO:0051138	biolink:NamedThing	positive regulation of NK T cell differentiation	Any process that activates or increases the frequency, rate or extent of natural killer T cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of natural T cell differentiation|stimulation of NK T cell differentiation|up-regulation of NK T cell differentiation|activation of NK T cell differentiation|positive regulation of NKT cell differentiation|upregulation of NK T cell differentiation|positive regulation of NK T-lymphocyte differentiation|positive regulation of NT cell differentiation|positive regulation of NK T-cell differentiation|positive regulation of NK T cell development|positive regulation of natural killer T cell differentiation|positive regulation of NK T lymphocyte differentiation|up regulation of NK T cell differentiation					Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.								biological_process											owl:Class	
GO:0015019	biolink:NamedThing	heparan-alpha-glucosaminide N-acetyltransferase activity	Catalysis of the reaction: acetyl-CoA + heparan alpha-D-glucosaminide = CoA + heparan N-acetyl-alpha-D-glucosaminide.	tmpzr1t_l9r_go_relaxed.owl	acetyl-CoA:heparan-alpha-D-glucosaminide N-acetyltransferase activity|acetyl-CoA:alpha-glucosaminide N-acetyltransferase activity|heparin-alpha-glucosaminide N-acetyltransferase activity				Reactome:R-HSA-9036056|Reactome:R-HSA-2090085|MetaCyc:2.3.1.78-RXN|RHEA:15125|EC:2.3.1.78|Reactome:R-HSA-1678660|Reactome:R-HSA-2263492									molecular_function											owl:Class	
GO:0039626	biolink:NamedThing	viral intermediate capsid	The intermediate layer of a triple concentric icosahedral capsid. Intermediate capsids are part of reoviridae virions.	tmpzr1t_l9r_go_relaxed.owl	intermediate capsid							bf	2012-07-18T04:06:25Z					cellular_component											owl:Class	
GO:0140668	biolink:NamedThing	positive regulation of oxytocin production	Any process that activates or increases the frequency, rate or extent of production of oxytocin.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/21535						pg	2021-06-24T11:31:26Z					biological_process											owl:Class	
GO:0031746	biolink:NamedThing	type 1 cysteinyl leukotriene receptor binding	Binding to a type 1 cysteinyl leukotriene receptor.	tmpzr1t_l9r_go_relaxed.owl	type 1 cysteinyl leukotriene receptor ligand													molecular_function											owl:Class	
GO:0003997	biolink:NamedThing	acyl-CoA oxidase activity	Catalysis of the reaction: acyl-CoA + O2 = trans-2,3-dehydroacyl-CoA + hydrogen peroxide.	tmpzr1t_l9r_go_relaxed.owl	fatty acyl-CoA oxidase activity|acyl coenzyme A oxidase activity|fatty acyl-coenzyme A oxidase activity|acyl-CoA:oxygen 2-oxidoreductase activity				Reactome:R-HSA-2066787|Reactome:R-HSA-192335|MetaCyc:ACYL-COA-OXIDASE-RXN|Reactome:R-HSA-390256|RHEA:38959|EC:1.3.3.6|Reactome:R-HSA-193369									molecular_function											owl:Class	
GO:0099621	biolink:NamedThing	undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase activity	Catalysis of the reaction: UDP-4-deoxy-4-formamido-beta-L-arabinopyranose + ditrans,octacis-undecaprenyl phosphate = UDP + 4-deoxy-4-formamido-alpha-L-arabinopyranosyl ditrans,octacis-undecaprenyl phosphate.	tmpzr1t_l9r_go_relaxed.owl	undecaprenyl phosphate-L-Ara4FN transferase activity|Ara4FN transferase activity|undecaprenyl-phosphate Ara4FN transferase activity				EC:2.4.2.53|MetaCyc:RXN0-3521|RHEA:27722							GO:0103019		molecular_function											owl:Class	
GO:0016573	biolink:NamedThing	histone acetylation	The modification of a histone by the addition of an acetyl group.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0010239	biolink:NamedThing	chloroplast mRNA processing	Steps involved in processing precursor RNAs arising from transcription of operons in the chloroplast genome into mature mRNAs.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0071209	biolink:NamedThing	U7 snRNA binding	Binding to a U7 small nuclear RNA (U7 snRNA).	tmpzr1t_l9r_go_relaxed.owl						Note that this term may be useful for annotating other small nuclear RNAs (snRNAs).		mah	2009-11-25T01:46:50Z					molecular_function											owl:Class	
GO:0047492	biolink:NamedThing	xanthan lyase activity	Catalysis of the reaction: xanthan = oligosaccharide with 4-deoxy-alpha-L-threo-hex-4-enuronosyl end + pyruvylate mannose. This reaction is the eliminative cleavage of the terminal beta-D-mannosyl-beta-D-1,4-glucuronosyl linkage of the side-chain of the polysaccharide xanthan, leaving a 4-deoxy-alpha-L-threo-hex-4-enuronosyl group at the terminus of the side-chain.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:4.2.2.12-RXN|EC:4.2.2.12									molecular_function											owl:Class	
GO:0015293	biolink:NamedThing	symporter activity	Enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported together in the same direction in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy.	tmpzr1t_l9r_go_relaxed.owl	symport|cotransporter activity|porter activity													molecular_function											owl:Class	
GO:1903594	biolink:NamedThing	negative regulation of histamine secretion by mast cell	Any process that stops, prevents or reduces the frequency, rate or extent of histamine secretion by mast cell.	tmpzr1t_l9r_go_relaxed.owl	inhibition of histamine secretion by mast cell|down-regulation of histamine secretion by mast cell|downregulation of histamine secretion by mast cell|down regulation of histamine secretion by mast cell							als	2014-11-06T13:19:18Z					biological_process											owl:Class	
GO:0044389	biolink:NamedThing	ubiquitin-like protein ligase binding	Binding to a ubiquitin-like protein ligase, such as ubiquitin-ligase.	tmpzr1t_l9r_go_relaxed.owl	small conjugating protein ligase binding|E3 protein ligase binding							jl	2011-12-15T04:33:20Z					molecular_function											owl:Class	
GO:0006751	biolink:NamedThing	glutathione catabolic process	The chemical reactions and pathways resulting in the breakdown of glutathione, the tripeptide glutamylcysteinylglycine, which acts as a coenzyme for some enzymes and as an antioxidant in the protection of sulfhydryl groups in enzymes and other proteins.	tmpzr1t_l9r_go_relaxed.owl	glutathione breakdown|glutathione degradation|glutathione catabolism													biological_process											owl:Class	
GO:0090425	biolink:NamedThing	acinar cell differentiation	The epithelial cell differentiation process in which a relatively unspecialized cell acquires specialized features of an acinar cell, a secretory cell that is grouped together with other cells of the same type to form grape-shaped clusters known as acini.	tmpzr1t_l9r_go_relaxed.owl								tb	2012-05-04T09:24:48Z					biological_process											owl:Class	
GO:0036154	biolink:NamedThing	diacylglycerol acyl-chain remodeling	Remodeling the acyl chains of diacylglycerol, through sequential deacylation and re-acylation reactions, to generate diacylglycerol containing different types of fatty acid acyl chains.	tmpzr1t_l9r_go_relaxed.owl	diglyceride acyl-chain remodeling							bf	2012-03-14T02:53:14Z					biological_process											owl:Class	
GO:0003139	biolink:NamedThing	secondary heart field specification	The process that results in the delineation of a specific region of the lateral mesoderm into the area which will form the majority of the mesodermal component of the right ventricle, arterial pole (outflow tract) and venous pole (inflow tract).	tmpzr1t_l9r_go_relaxed.owl	second heart field specification|anterior heart field specification|SHF specification							tb	2009-09-22T03:47:56Z					biological_process											owl:Class	
GO:0032692	biolink:NamedThing	negative regulation of interleukin-1 production	Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-1 production.	tmpzr1t_l9r_go_relaxed.owl	inhibition of interleukin-1 production|negative regulation of IL-1 production|down-regulation of interleukin-1 production|negative regulation of interleukin-1 biosynthetic process|negative regulation of interleukin-1 secretion|downregulation of interleukin-1 production|down regulation of interleukin-1 production											GO:0045361|GO:0050711		biological_process											owl:Class	
GO:0047526	biolink:NamedThing	2'-hydroxyisoflavone reductase activity	Catalysis of the reaction: vestitone + NADP+ = 2'-hydroxyformononetin + NADPH + H+.	tmpzr1t_l9r_go_relaxed.owl	NADPH:2'-hydroxyisoflavone oxidoreductase activity|vestitone:NADP+ oxidoreductase activity|2',7-dihydroxy-4',5'-methylenedioxyisoflavone reductase activity|isoflavone reductase activity				RHEA:22560|EC:1.3.1.45|MetaCyc:2-HYDROXYISOFLAVONE-REDUCTASE-RXN									molecular_function											owl:Class	
GO:0046486	biolink:NamedThing	glycerolipid metabolic process	The chemical reactions and pathways involving glycerolipids, any lipid with a glycerol backbone. Diacylglycerol and phosphatidate are key lipid intermediates of glycerolipid biosynthesis.	tmpzr1t_l9r_go_relaxed.owl	glycerolipid metabolism													biological_process											owl:Class	
GO:0070811	biolink:NamedThing	glycerol-2-phosphate transmembrane transport	The process in which glycerol-2-phosphate is transported across a membrane. Glycerol-2-phosphate is a phosphoric monoester of glycerol.	tmpzr1t_l9r_go_relaxed.owl	glycerol-2-phosphate transport							mah	2009-07-08T04:57:38Z					biological_process											owl:Class	
GO:0009168	biolink:NamedThing	purine ribonucleoside monophosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of purine ribonucleoside monophosphate, a compound consisting of a purine base linked to a ribose sugar esterified with phosphate on the sugar.	tmpzr1t_l9r_go_relaxed.owl	purine ribonucleoside monophosphate formation|purine ribonucleoside monophosphate biosynthesis|purine ribonucleoside monophosphate anabolism|purine ribonucleoside monophosphate synthesis													biological_process											owl:Class	
GO:0140341	biolink:NamedThing	phosphatidylethanolamine floppase activity	Catalysis of the movement of phosphatidylethanolamine from the cytosolic to the exoplasmic leaftlet of a membrane, using energy from the hydrolysis of ATP.	tmpzr1t_l9r_go_relaxed.owl	phosphatidylethanolamine floppase activity (cytosolic to exoplasmic leaftlet)							pg	2019-05-16T11:40:45Z					molecular_function											owl:Class	
GO:0071025	biolink:NamedThing	RNA surveillance	The set of processes involved in identifying and degrading defective or aberrant RNAs.	tmpzr1t_l9r_go_relaxed.owl	aberrant RNA catabolic process|RNA quality control							krc	2009-07-28T03:10:28Z					biological_process											owl:Class	
GO:0032936	biolink:NamedThing	SREBP-SCAP complex	A protein complex formed by the association of sterol regulatory element binding protein (SREBP) and SREBP-cleavage-activating protein (SCAP) in the ER membrane; in the absence of sterols, the SREBP-SCAP complex is packaged into COPII vesicles and travels to the Golgi apparatus to be processed.	tmpzr1t_l9r_go_relaxed.owl	Sre1-Scp1 complex													cellular_component											owl:Class	
GO:0034181	biolink:NamedThing	positive regulation of toll-like receptor 13 signaling pathway	Any process that activates or increases the frequency, rate, or extent of toll-like receptor 13 signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of toll-like receptor 13 signalling pathway|positive regulation of TLR13 signaling pathway													biological_process											owl:Class	
GO:0004351	biolink:NamedThing	glutamate decarboxylase activity	Catalysis of the reaction: L-glutamate = 4-aminobutanoate + CO2.	tmpzr1t_l9r_go_relaxed.owl	L-glutamic acid decarboxylase activity|cysteic acid decarboxylase activity|aspartic alpha-decarboxylase|L-glutamate alpha-decarboxylase activity|L-glutamic decarboxylase activity|L-glutamate 1-carboxy-lyase (4-aminobutanoate-forming)|L-aspartate-alpha-decarboxylase activity|L-glutamate 1-carboxy-lyase activity|gamma-glutamate decarboxylase activity				EC:4.1.1.15|RHEA:17785|Reactome:R-HSA-888577|MetaCyc:GLUTDECARBOX-RXN|Reactome:R-HSA-888572									molecular_function											owl:Class	
GO:0043472	biolink:NamedThing	IgD binding	Binding to an immunoglobulin of a D isotype.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0044824	biolink:NamedThing	retroviral 3' processing activity	The catalysis of the removal of two di- or tri-nucleotides from each 3' end of double-stranded viral DNA, exposing recessed 3' hydroxyls.	tmpzr1t_l9r_go_relaxed.owl	3' processing reaction|3'-processing activity					This reaction may serve to remove heterogeneous extra bases from the viral DNA end, and to stabilize the integrase-DNA complex. The chemistry of cleavage is a simple hydrolysis by single-step transesterification.		jl	2014-02-04T14:51:24Z					molecular_function											owl:Class	
GO:0048937	biolink:NamedThing	lateral line nerve glial cell development	The process aimed at the progression of a lateral line glial cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0045227	biolink:NamedThing	capsule polysaccharide biosynthetic process	The chemical reactions and pathways resulting in the formation of polysaccharides that make up the capsule, a protective structure surrounding some species of bacteria and fungi.	tmpzr1t_l9r_go_relaxed.owl	capsular polysaccharide biosynthetic process|capsule polysaccharide synthesis|capsule polysaccharide biosynthesis|capsule polysaccharide anabolism|capsule polysaccharide formation|capsular polysaccharide biosynthesis													biological_process											owl:Class	
GO:2000981	biolink:NamedThing	negative regulation of inner ear receptor cell differentiation	Any process that stops, prevents or reduces the frequency, rate or extent of inner ear receptor cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of inner ear hair cell differentiation							yaf	2011-08-03T02:38:47Z					biological_process											owl:Class	
GO:0015541	biolink:NamedThing	secondary active cyanate transmembrane transporter activity	Enables the transfer of cyanate from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	cyanate porter activity													molecular_function											owl:Class	
GO:0031946	biolink:NamedThing	regulation of glucocorticoid biosynthetic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glucocorticoids.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0042440	biolink:NamedThing	pigment metabolic process	The chemical reactions and pathways involving pigment, any general or particular coloring matter in living organisms, e.g. melanin.	tmpzr1t_l9r_go_relaxed.owl	pigment metabolism													biological_process											owl:Class	
GO:1905485	biolink:NamedThing	positive regulation of motor neuron migration	Any process that activates or increases the frequency, rate or extent of motor neuron migration.	tmpzr1t_l9r_go_relaxed.owl	upregulation of motor neuron migration|up regulation of motor neuron migration|activation of motor neuron migration|up-regulation of motor neuron migration							hbye	2016-09-23T12:50:19Z					biological_process											owl:Class	
GO:0044631	biolink:NamedThing	positive regulation of complement activation, lectin pathway in other organism	Any process that activates or increases the frequency, rate or extent of complement activation by the lectin pathway, in a different organism.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-07-05T01:17:33Z					biological_process											owl:Class	
GO:0045587	biolink:NamedThing	negative regulation of gamma-delta T cell differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of gamma-delta T cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of gamma-delta T-lymphocyte differentiation|negative regulation of gamma-delta T lymphocyte differentiation|downregulation of gamma-delta T cell differentiation|down-regulation of gamma-delta T cell differentiation|negative regulation of gamma-delta T cell development|inhibition of gamma-delta T cell differentiation|down regulation of gamma-delta T cell differentiation|negative regulation of gamma-delta T-cell differentiation					Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.								biological_process											owl:Class	
GO:0015691	biolink:NamedThing	cadmium ion transport	The directed movement of cadmium (Cd) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	cadmium transport													biological_process											owl:Class	
GO:0000041	biolink:NamedThing	transition metal ion transport	The directed movement of transition metal ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A transition metal is an element whose atom has an incomplete d-subshell of extranuclear electrons, or which gives rise to a cation or cations with an incomplete d-subshell. Transition metals often have more than one valency state. Biologically relevant transition metals include vanadium, manganese, iron, copper, cobalt, nickel, molybdenum and silver.	tmpzr1t_l9r_go_relaxed.owl	transition metal transport													biological_process											owl:Class	
GO:0017174	biolink:NamedThing	glycine N-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + glycine = S-adenosyl-L-homocysteine + sarcosine.	tmpzr1t_l9r_go_relaxed.owl	glycine methyltransferase activity|S-adenosyl-L-methionine:glycine methyltransferase activity|GNMT|S-adenosyl-L-methionine:glycine N-methyltransferase activity				MetaCyc:2.1.1.162-RXN|EC:2.1.1.162|EC:2.1.1.156|MetaCyc:GLYCINE-N-METHYLTRANSFERASE-RXN|RHEA:19937|Reactome:R-HSA-6798317|KEGG_REACTION:R00367|EC:2.1.1.20									molecular_function											owl:Class	
GO:0098636	biolink:NamedThing	protein complex involved in cell adhesion	Any protein complex that is capable of carrying out some part of the process of cell adhesion to the cell matrix or to another cell.	tmpzr1t_l9r_go_relaxed.owl	cell adhesion complex											GO:1990307		cellular_component											owl:Class	
GO:0062239	biolink:NamedThing	heterochromatin-nuclear membrane anchor activity	Binding to heterochromatin and the nuclear inner membrane, in order to establish and maintain the heterochromatin location and organization.	tmpzr1t_l9r_go_relaxed.owl	heterochromatin-nuclear membrane tether activity|nuclear membrane-heterochromatin tether activity|nuclear membrane-heterochromatin anchor activity							dph	2020-04-20T18:20:36Z					molecular_function											owl:Class	
GO:0140707	biolink:NamedThing	chromatin-nuclear membrane anchor activity	Binding to chromatin and the nuclear inner membrane, in order to establish and maintain the heterochromatin location and organization, or to enable equal segregation of the nuclear membrane during mitosis.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/22081						pg	2021-09-02T06:18:21Z					molecular_function											owl:Class	
GO:0106150	biolink:NamedThing	zearalenone biosynthetic process	The chemical reactions and pathways resulting in the formation of zearalenone, a mycotoxin produced by several Fusarium species, is most commonly found as a contaminant in stored grain and has chronic estrogenic effects on mammals.	tmpzr1t_l9r_go_relaxed.owl								hjd	2018-09-14T17:08:18Z					biological_process											owl:Class	
GO:0033068	biolink:NamedThing	macrolide biosynthetic process	The chemical reactions and pathways leading to the formation of macrolides, any of a large group of polyketide compounds that contain a large lactone ring with few or no double bonds and no nitrogen atoms, linked glycosidically to one or more sugar groups. The macrolides include the carbomycins, the erythromycins, oleandomycin, oligomycins, and the spiramycins, and act as antibiotics, mainly against Gram-positive bacteria.	tmpzr1t_l9r_go_relaxed.owl	macrolide anabolism|macrolide formation|macrolide synthesis|macrolide biosynthesis													biological_process											owl:Class	
GO:0075227	biolink:NamedThing	regulation of encysted zoospore germination	Any process that modulates the frequency, rate or extent of an encysted zoospore germination.	tmpzr1t_l9r_go_relaxed.owl	modulation of encysted zoospore germination on or near host|regulation of encysted zoospore germination on or near host													biological_process											owl:Class	
GO:0060472	biolink:NamedThing	positive regulation of cortical granule exocytosis by positive regulation of cytosolic calcium ion concentration	Any process that activates or increases the frequency, rate or extent of cortical granule exocytosis by directing movement of calcium ions (Ca2+) into the cytosol.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of cortical granule exocytosis by elevation of cytosolic calcium ion concentration													biological_process											owl:Class	
GO:0090732	biolink:NamedThing	cofilin-actin rod	A cellular structure consisting of parallel, hexagonally arranged actin tubules, comprising filamentous actin and disulfide cross-linked cofilin multimers.	tmpzr1t_l9r_go_relaxed.owl								tb	2017-01-31T17:44:04Z					cellular_component											owl:Class	
GO:0031002	biolink:NamedThing	actin rod	A cellular structure consisting of parallel, hexagonally arranged actin tubules, comprising filamentous actin and associated proteins. Actin rod structures are found in diverse organisms, having been observed in spores of Dictyostelium discoideum, Drosophila melanogaster oocytes, as well as in numerous animal cells under stress conditions.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0021558	biolink:NamedThing	trochlear nerve development	The process whose specific outcome is the progression of the trochlear nerve over time, from its formation to the mature structure. The trochlear nerve is a motor nerve and is the only cranial nerve to exit the brain dorsally. The trochlear nerve innervates the superior oblique muscle.	tmpzr1t_l9r_go_relaxed.owl	cranial nerve IV development|cranial nerve 4 development|CN IV development													biological_process											owl:Class	
GO:0043165	biolink:NamedThing	Gram-negative-bacterium-type cell outer membrane assembly	The assembly of an outer membrane of the type formed in Gram-negative bacteria. This membrane is enriched in polysaccharide and protein, and the outer leaflet of the membrane contains specific lipopolysaccharide structures.	tmpzr1t_l9r_go_relaxed.owl	cell outer membrane biogenesis													biological_process											owl:Class	
GO:1903143	biolink:NamedThing	adrenomedullin receptor complex	A transmembrane, G protein-coupled signalling receptor complex which is capable of adrenomedullin receptor activity.	tmpzr1t_l9r_go_relaxed.owl	adrenomedullin receptor AM1 complex|adrenomedullin receptor AM2 complex					An example of this is RAMP2 in human (O60895) in PMID:22102369 (inferred from direct assay).		bhm	2014-07-02T08:56:47Z					cellular_component											owl:Class	
GO:0042363	biolink:NamedThing	fat-soluble vitamin catabolic process	The chemical reactions and pathways resulting in the breakdown of any of a diverse group of vitamins that are soluble in organic solvents and relatively insoluble in water.	tmpzr1t_l9r_go_relaxed.owl	fat-soluble vitamin catabolism|fat-soluble vitamin degradation|fat-soluble vitamin breakdown													biological_process											owl:Class	
GO:0004458	biolink:NamedThing	D-lactate dehydrogenase (cytochrome) activity	Catalysis of the reaction: (R)-lactate + 2 [Fe(III)cytochrome c] = 2 [Fe(II)cytochrome c] + 2 H+ + pyruvate.	tmpzr1t_l9r_go_relaxed.owl	cytochrome-dependent D-(-)-lactate dehydrogenase activity|D-lactate-cytochrome c reductase activity|D-lactate (cytochrome) dehydrogenase activity|D-(-)-lactic cytochrome c reductase activity|(R)-lactate:ferricytochrome-c 2-oxidoreductase activity|lactic acid dehydrogenase activity|D-lactate ferricytochrome c oxidoreductase activity				RHEA:13521|EC:1.1.2.4|MetaCyc:D-LACTATE-DEHYDROGENASE-CYTOCHROME-RXN									molecular_function											owl:Class	
GO:0034212	biolink:NamedThing	peptide N-acetyltransferase activity	Catalysis of the acetylation of an amino acid residue of a peptide or protein, according to the reaction: acetyl-CoA + peptide = CoA + N-acetylpeptide.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-3371554									molecular_function											owl:Class	
GO:0046252	biolink:NamedThing	toluene biosynthetic process	The chemical reactions and pathways resulting in the formation of toluene, a volatile monoaromatic hydrocarbon found in crude petroleum and petroleum products.	tmpzr1t_l9r_go_relaxed.owl	toluene synthesis|toluene biosynthesis|toluene anabolism|toluene formation					This term was reinstated from obsolete.								biological_process											owl:Class	
GO:0019145	biolink:NamedThing	aminobutyraldehyde dehydrogenase activity	Catalysis of the reaction: 4-aminobutanal + NAD+ + H2O = 4-aminobutanoate + NADH + 2 H+.	tmpzr1t_l9r_go_relaxed.owl	4-aminobutanal dehydrogenase activity|4-aminobutyraldehyde dehydrogenase activity|ABAL dehydrogenase activity|4-aminobutanal:NAD+ 1-oxidoreductase activity|gamma-aminobutyraldehyde dehydroganase activity				MetaCyc:AMINOBUTDEHYDROG-RXN|EC:1.2.1.19|RHEA:19105									molecular_function											owl:Class	
GO:0102409	biolink:NamedThing	sn-2-glycerol-3-phosphate C16:0-CoA acyl transferase activity	Catalysis of the reaction: behenoyl-CoA + sn-glycerol 3-phosphate(2-) <=> coenzyme A + 2-docosanoyl-glycerol 3-phosphate.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-13736									molecular_function											owl:Class	
GO:0061718	biolink:NamedThing	glucose catabolic process to pyruvate	The chemical reactions and pathways resulting in the breakdown of glucose, with the production of pyruvate.	tmpzr1t_l9r_go_relaxed.owl	glucose catabolism to pyruvate							dph	2015-06-30T13:17:26Z					biological_process											owl:Class	
GO:0072683	biolink:NamedThing	T cell extravasation	The migration of a T cell from the blood vessels into the surrounding tissue.	tmpzr1t_l9r_go_relaxed.owl	T-lymphocyte extravasation|T-cell extravasation|T lymphocyte extravasation							mah	2011-02-22T04:05:45Z					biological_process											owl:Class	
GO:0007383	biolink:NamedThing	specification of segmental identity, antennal segment	The specification of the characteristic structures of the antennal segment following establishment of segment boundaries. Identity is considered to be the aggregate of characteristics by which a structure is recognized.	tmpzr1t_l9r_go_relaxed.owl						See also the fly_anatomy.ontology term 'antennal segment ; FBbt:00000009'.								biological_process											owl:Class	
GO:0004781	biolink:NamedThing	sulfate adenylyltransferase (ATP) activity	Catalysis of the reaction: ATP + sulfate = diphosphate + adenylylsulfate.	tmpzr1t_l9r_go_relaxed.owl	ATP-sulfurylase activity|sulfate adenylate transferase activity|sulphate adenylyltransferase (ATP) activity|adenosinetriphosphate sulfurylase activity|adenosine-5'-triphosphate sulfurylase activity|adenylylsulfate pyrophosphorylase activity|ATP:sulfate adenylyltransferase activity|ATP sulfurylase activity|sulfurylase activity				Reactome:R-HSA-174392|MetaCyc:SULFATE-ADENYLYLTRANS-RXN|RHEA:18133|EC:2.7.7.4|Reactome:R-HSA-3560794									molecular_function											owl:Class	
GO:0004779	biolink:NamedThing	sulfate adenylyltransferase activity	Catalysis of the transfer of an adenylyl group from an adenosine nucleotide (ATP or ADP) to sulfate, forming adenylylsulfate.	tmpzr1t_l9r_go_relaxed.owl	sulphate adenylyltransferase activity													molecular_function											owl:Class	
GO:0070631	biolink:NamedThing	spindle pole body localization	Any process in which a spindle pole body is transported to, or maintained in, a specific location. A spindle pole body is a type of microtubule organizing center found in fungal cells.	tmpzr1t_l9r_go_relaxed.owl	spindle pole body localisation|maintenance of spindle pole body localization	https://github.com/geneontology/go-ontology/issues/19149						mah	2009-05-06T02:21:38Z			GO:1990944|GO:0071790		biological_process											owl:Class	
GO:0061842	biolink:NamedThing	microtubule organizing center localization	Any process in which the microtubule organizing center is transported to, and/or maintained in, a specific location within the cell.	tmpzr1t_l9r_go_relaxed.owl	MTOC localization|MTOC polarity|microtubule organizing center polarity													biological_process											owl:Class	
GO:0090224	biolink:NamedThing	regulation of spindle organization	Any process that modulates the rate, frequency or extent of the assembly, arrangement of constituent parts, or disassembly of the microtubule spindle.	tmpzr1t_l9r_go_relaxed.owl	regulation of spindle organisation							tb	2010-01-13T11:04:53Z					biological_process											owl:Class	
GO:0015114	biolink:NamedThing	phosphate ion transmembrane transporter activity	Enables the transfer of phosphate (PO4 3-) ions from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	phosphate transmembrane transporter activity				RHEA:32823			pr	2012-11-22T15:43:10Z			GO:1901677		molecular_function											owl:Class	
GO:0052681	biolink:NamedThing	alpha-bisabolene synthase activity	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = (E,R)-alpha-bisabolene + diphosphate.	tmpzr1t_l9r_go_relaxed.owl	(2E,6E)-farnesyl-diphosphate diphosphate-lyase [(E)-alpha-bisabolene-forming] activity|bisabolene synthase activity				EC:4.2.3.38|RHEA:25436|KEGG_REACTION:R08370|MetaCyc:RXN-8550									molecular_function											owl:Class	
GO:0009305	biolink:NamedThing	protein biotinylation	The addition of biotin (vitamin B7 / vitamin H) to a protein amino acid.	tmpzr1t_l9r_go_relaxed.owl	protein amino acid biotinylation													biological_process											owl:Class	
GO:0022016	biolink:NamedThing	pallium glioblast division	The division of a glioblast in the pallium. A glioblast is a dividing precursor cell that gives rise to glial cells.	tmpzr1t_l9r_go_relaxed.owl	glioblast cell division in pallium													biological_process											owl:Class	
GO:0102522	biolink:NamedThing	tRNA 4-demethylwyosine alpha-amino-alpha-carboxypropyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine  + 4-demethylwyosine37 in tRNAPhe <=> 5'-S-methyl-5'-thioadenosine + H+ + 7-[(3S)-3-amino-3-carboxypropyl]-4-demethylwyosine37 in tRNAPhe.	tmpzr1t_l9r_go_relaxed.owl					RHEA:36355|MetaCyc:RXN-14518|EC:2.5.1.114									molecular_function											owl:Class	
GO:1901871	biolink:NamedThing	ecgonone methyl ester catabolic process	The chemical reactions and pathways resulting in the breakdown of ecgonone methyl ester.	tmpzr1t_l9r_go_relaxed.owl	ecgonone methyl ester catabolism|ecgonone methyl ester breakdown|ecgonone methyl ester degradation							ms	2013-02-04T11:58:34Z					biological_process											owl:Class	
GO:0070256	biolink:NamedThing	negative regulation of mucus secretion	Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of mucus from a cell or a tissue.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of mucus production													biological_process											owl:Class	
GO:0009094	biolink:NamedThing	L-phenylalanine biosynthetic process	The chemical reactions and pathways resulting in the formation of L-phenylalanine, the L-enantiomer of 2-amino-3-phenylpropanoic acid, i.e. (2S)-2-amino-3-phenylpropanoic acid.	tmpzr1t_l9r_go_relaxed.owl	L-phenylalanine synthesis|phenylalanine biosynthetic process|phenylalanine biosynthesis|L-phenylalanine biosynthesis|phenylalanine biosynthetic process, shikimate pathway|phenylalanine biosynthetic process, prephenate pathway|L-phenylalanine anabolism|L-phenylalanine formation											GO:0019275|GO:0019274		biological_process											owl:Class	
GO:1902447	biolink:NamedThing	negative regulation of shade avoidance	Any process that stops, prevents or reduces the frequency, rate or extent of shade avoidance.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of shade avoidance|down regulation of shade avoidance|inhibition of shade avoidance|downregulation of shade avoidance							dhl	2013-10-15T21:04:51Z					biological_process											owl:Class	
GO:1902446	biolink:NamedThing	regulation of shade avoidance	Any process that modulates the frequency, rate or extent of shade avoidance.	tmpzr1t_l9r_go_relaxed.owl								dhl	2013-10-15T21:04:36Z					biological_process											owl:Class	
GO:1902891	biolink:NamedThing	negative regulation of root hair elongation	Any process that stops, prevents or reduces the frequency, rate or extent of root hair elongation.	tmpzr1t_l9r_go_relaxed.owl	inhibition of root hair elongation|down regulation of root hair elongation|downregulation of root hair elongation|down-regulation of root hair elongation							als	2014-04-07T13:46:47Z					biological_process											owl:Class	
GO:1903778	biolink:NamedThing	protein localization to vacuolar membrane	A process in which a protein is transported to, or maintained in, a location within a vacuolar membrane.	tmpzr1t_l9r_go_relaxed.owl	protein localization in vacuolar membrane|protein localisation in vacuolar membrane|protein localisation to vacuolar membrane							mah	2015-01-07T13:15:54Z					biological_process											owl:Class	
GO:0033519	biolink:NamedThing	phytyl diphosphate metabolic process	The chemical reactions and pathways involving phytyl diphosphate, (2E)-3,7,11,15-tetramethylhexadec-2-en-1-yl trihydrogen diphosphate.	tmpzr1t_l9r_go_relaxed.owl	phytyl diphosphate metabolism													biological_process											owl:Class	
GO:0046186	biolink:NamedThing	acetaldehyde biosynthetic process	The chemical reactions and pathways resulting in the formation of acetaldehyde, a colorless, flammable liquid intermediate in the metabolism of alcohol.	tmpzr1t_l9r_go_relaxed.owl	acetaldehyde formation|acetaldehyde synthesis|acetaldehyde anabolism|acetaldehyde biosynthesis													biological_process											owl:Class	
GO:0006117	biolink:NamedThing	acetaldehyde metabolic process	The chemical reactions and pathways involving acetaldehyde, a colorless, flammable liquid intermediate in the metabolism of alcohol.	tmpzr1t_l9r_go_relaxed.owl	acetaldehyde metabolism|ethanal metabolism|ethanal metabolic process													biological_process											owl:Class	
GO:0052757	biolink:NamedThing	chondroitin hydrolase activity	Catalysis of the hydrolysis of hexosaminic linkages in chondroitin, a linear polymer structure composed of the repeating disaccharide unit [->4)-D-glucuronic acid-(1->3)-N-acetyl-D-galactosamine-(1-], also written as [->4GlcUA1->3GalNAc1-].	tmpzr1t_l9r_go_relaxed.owl	chondroitin endo-beta-galactosaminidase activity							ai	2011-09-28T10:31:53Z					molecular_function											owl:Class	
GO:0033931	biolink:NamedThing	endogalactosaminidase activity	Catalysis of the endohydrolysis of (1->4)-alpha-D-galactosaminidic linkages in poly(D-galactosamine).	tmpzr1t_l9r_go_relaxed.owl	galactosaminoglycan glycanohydrolase activity				MetaCyc:3.2.1.109-RXN|EC:3.2.1.109									molecular_function											owl:Class	
GO:1903298	biolink:NamedThing	negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway	Any process that stops, prevents or reduces the frequency, rate or extent of hypoxia-induced intrinsic apoptotic signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of hypoxic stress-induced intrinsic apoptotic signaling pathway|negative regulation of intrinsic apoptotic signaling pathway in response to hypoxia|down-regulation of intrinsic apoptotic signaling pathway in response to hypoxia|protection against hypoxia-induced apoptosis|down regulation of intrinsic apoptotic signaling pathway in response to hypoxia|downregulation of intrinsic apoptotic signaling pathway in response to hypoxia|negative regulation of hypoxia-induced apoptosis|inhibition of intrinsic apoptotic signaling pathway in response to hypoxia							bf	2014-08-14T14:47:56Z					biological_process											owl:Class	
GO:0009130	biolink:NamedThing	pyrimidine nucleoside monophosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of pyrimidine nucleoside monophosphate, a compound consisting of a pyrimidine base linked to a ribose or deoxyribose sugar esterified with phosphate on the sugar.	tmpzr1t_l9r_go_relaxed.owl	pyrimidine nucleoside monophosphate synthesis|pyrimidine nucleoside monophosphate anabolism|pyrimidine nucleoside monophosphate formation|pyrimidine nucleoside monophosphate biosynthesis													biological_process											owl:Class	
GO:0047329	biolink:NamedThing	phosphoramidate-hexose phosphotransferase activity	Catalysis of the reaction: hexose + phosphoramidate = hexose 1-phosphate + NH3.	tmpzr1t_l9r_go_relaxed.owl	phosphoramidic-hexose transphosphorylase activity|phosphoramidate-hexose transphosphorylase activity|phosphoramidate:hexose 1-phosphotransferase activity				MetaCyc:2.7.1.62-RXN|EC:2.7.1.62|RHEA:10972									molecular_function											owl:Class	
GO:0098956	biolink:NamedThing	intrinsic component of dense core granule membrane	The component of the dense core granule membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.	tmpzr1t_l9r_go_relaxed.owl	intrinsic to dense core granule membrane													cellular_component											owl:Class	
GO:0102038	biolink:NamedThing	4-nitrobenzyl alcohol oxidase activity	Catalysis of the reaction: 4-nitrobenzyl alcohol + O2 <=> 4-nitrobenzaldehyde + hydrogen peroxide.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:R362-RXN									molecular_function											owl:Class	
GO:0018592	biolink:NamedThing	4-nitrocatechol 4-monooxygenase activity	Catalysis of the reaction: 4-nitrocatechol + O2 + 4 e- + 3 H+ = H2O + nitrite + 1,2,4-benzenetriol.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0231|EC:1.14.13.166									molecular_function											owl:Class	
GO:1990749	biolink:NamedThing	polynucleotide adenylyltransferase activator activity	Increases the activity of the enzyme polynucleotide adenylyltransferase.	tmpzr1t_l9r_go_relaxed.owl								kmv	2015-05-19T15:02:39Z					molecular_function											owl:Class	
GO:0008335	biolink:NamedThing	female germline ring canal stabilization	Maintenance of the structural integrity of the ring canals connecting the female germline cyst.	tmpzr1t_l9r_go_relaxed.owl	ovarian ring canal stabilization|nurse cell ring canal stabilization													biological_process											owl:Class	
GO:0034414	biolink:NamedThing	tRNA 3'-trailer cleavage, endonucleolytic	Endonucleolytic cleavage of the 3'-end of the pre-tRNA as part of the process of generating the mature 3'-end of the tRNA.	tmpzr1t_l9r_go_relaxed.owl	tRNA 3'-end cleavage, endonucleolytic|endonucleolytic tRNA 3'-end cleavage|endonucleolytic tRNA 3'-trailer cleavage													biological_process											owl:Class	
GO:1901408	biolink:NamedThing	negative regulation of phosphorylation of RNA polymerase II C-terminal domain	Any process that stops, prevents or reduces the frequency, rate or extent of phosphorylation of RNA polymerase II C-terminal domain.	tmpzr1t_l9r_go_relaxed.owl	downregulation of generation of hyperphosphorylated CTD of RNA polymerase II|inhibition of hyperphosphorylation of RNA polymerase II C-terminal domain|down-regulation of CTD domain phosphorylation of RNA polymerase II|down-regulation of generation of II(0) form of RNA polymerase II|down regulation of generation of II(0) form of RNA polymerase II|downregulation of generation of II(0) form of RNA polymerase II|down regulation of CTD domain phosphorylation of RNA polymerase II|inhibition of generation of hyperphosphorylated CTD of RNA polymerase II|negative regulation of generation of II(0) form of RNA polymerase II|down regulation of hyperphosphorylation of RNA polymerase II C-terminal domain|down regulation of phosphorylation of RNA polymerase II C-terminal domain|inhibition of generation of II(0) form of RNA polymerase II|inhibition of phosphorylation of RNA polymerase II C-terminal domain|negative regulation of hyperphosphorylation of RNA polymerase II C-terminal domain|down-regulation of hyperphosphorylation of RNA polymerase II C-terminal domain|downregulation of phosphorylation of RNA polymerase II C-terminal domain|negative regulation of generation of hyperphosphorylated CTD of RNA polymerase II|negative regulation of CTD domain phosphorylation of RNA polymerase II|inhibition of CTD domain phosphorylation of RNA polymerase II|down regulation of generation of hyperphosphorylated CTD of RNA polymerase II|downregulation of hyperphosphorylation of RNA polymerase II C-terminal domain|downregulation of CTD domain phosphorylation of RNA polymerase II|down-regulation of phosphorylation of RNA polymerase II C-terminal domain|down-regulation of generation of hyperphosphorylated CTD of RNA polymerase II							vw	2012-10-01T14:40:58Z					biological_process											owl:Class	
GO:1904561	biolink:NamedThing	cellular response to diphenidol	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diphenidol stimulus.	tmpzr1t_l9r_go_relaxed.owl								mr	2015-08-14T16:09:37Z					biological_process											owl:Class	
GO:0002004	biolink:NamedThing	secretion of vasopressin involved in fast regulation of systemic arterial blood pressure	The regulated release of the hormone vasopressin into the blood stream by the hypothalamus and pituitary gland contributing to fast regulation of blood pressure.	tmpzr1t_l9r_go_relaxed.owl	secretion of vasopressin during fast regulation of systemic arterial blood pressure|secretion of vasopressin during fast control of blood pressure													biological_process											owl:Class	
GO:0030103	biolink:NamedThing	vasopressin secretion	The regulated release of vasopressin from secretory granules into the blood.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1903817	biolink:NamedThing	negative regulation of voltage-gated potassium channel activity	Any process that stops, prevents or reduces the frequency, rate or extent of voltage-gated potassium channel activity.	tmpzr1t_l9r_go_relaxed.owl	down regulation of voltage gated potassium channel activity|negative regulation of voltage-gated potassium ion channel activity|downregulation of voltage-dependent potassium channel activity|downregulation of voltage-sensitive potassium channel|down-regulation of voltage-gated potassium ion channel activity|downregulation of voltage gated potassium channel activity|down-regulation of voltage-sensitive potassium channel|down regulation of voltage-gated potassium channel activity|down regulation of voltage-sensitive potassium channel|negative regulation of voltage-sensitive potassium channel|inhibition of voltage gated potassium channel activity|inhibition of voltage-sensitive potassium channel|negative regulation of voltage gated potassium channel activity|down regulation of voltage-dependent potassium channel activity|negative regulation of voltage-dependent potassium channel activity|down-regulation of voltage-dependent potassium channel activity|inhibition of voltage-gated potassium channel activity|inhibition of voltage-gated potassium ion channel activity|down-regulation of voltage-gated potassium channel activity|down-regulation of voltage gated potassium channel activity|inhibition of voltage-dependent potassium channel activity|down regulation of voltage-gated potassium ion channel activity|downregulation of voltage-gated potassium channel activity|downregulation of voltage-gated potassium ion channel activity							sl	2015-01-16T17:22:08Z					biological_process											owl:Class	
GO:0002918	biolink:NamedThing	negative regulation of peripheral B cell anergy	Any process that stops, prevents, or reduces the frequency, rate, or extent of peripheral B cell anergy.	tmpzr1t_l9r_go_relaxed.owl	down regulation of peripheral B cell anergy|inhibition of peripheral B cell anergy|downregulation of peripheral B cell anergy|down-regulation of peripheral B cell anergy													biological_process											owl:Class	
GO:0019148	biolink:NamedThing	D-cysteine desulfhydrase activity	Catalysis of the reaction: D-cysteine + H2O = sulfide + NH3 + pyruvate.	tmpzr1t_l9r_go_relaxed.owl	D-cysteine sulfide-lyase (deaminating)|D-cysteine lyase activity|D-cysteine sulfide-lyase (deaminating; pyruvate-forming)				EC:4.4.1.15|MetaCyc:DCYSDESULF-RXN|RHEA:11268									molecular_function											owl:Class	
GO:0004119	biolink:NamedThing	cGMP-inhibited cyclic-nucleotide phosphodiesterase activity	Catalysis of the reaction: nucleoside 3',5'-cyclic phosphate + H2O = nucleoside 5'-phosphate; catalytic activity is decreased in the presence of cGMP.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0004114	biolink:NamedThing	3',5'-cyclic-nucleotide phosphodiesterase activity	Catalysis of the reaction: nucleoside 3',5'-cyclic phosphate + H2O = nucleoside 5'-phosphate.	tmpzr1t_l9r_go_relaxed.owl	3': 5'-monophosphate phosphodiesterase (cyclic CMP) activity|cyclic AMP phosphodiesterase activity|cyclic 3',5'-phosphodiesterase activity|3',5'-cyclonucleotide phosphodiesterase activity|3', 5'-cyclic nucleoside monophosphate phosphodiesterase activity|nucleoside-3',5-monophosphate phosphodiesterase activity|cyclic nucleotide phosphodiesterase activity|nucleoside 3',5'-cyclic phosphate diesterase activity|cytidine 3':5'-monophosphate phosphodiesterase (cyclic CMP) activity|3',5'-cyclic-nucleotide 5'-nucleotidohydrolase activity|3',5' cyclic-nucleotide phosphodiesterase activity|3':5'-cyclic nucleotide 5'-nucleotidohydrolase activity|PDE|3',5'-nucleotide phosphodiesterase activity|cyclic 3',5'-mononucleotide phosphodiesterase activity|cyclic 3',5-nucleotide monophosphate phosphodiesterase activity|cyclic 3',5'-nucleotide phosphodiesterase activity				MetaCyc:3.1.4.17-RXN|EC:3.1.4.17|RHEA:14653|Reactome:R-HSA-162425									molecular_function											owl:Class	
GO:1901074	biolink:NamedThing	regulation of engulfment of apoptotic cell	Any process that modulates the frequency, rate or extent of engulfment of apoptotic cell.	tmpzr1t_l9r_go_relaxed.owl	regulation of engulfment of cell corpse|regulation of engulfment of apoptotic cell corpse							kmv	2012-07-02T07:32:21Z					biological_process											owl:Class	
GO:0072160	biolink:NamedThing	nephron tubule epithelial cell differentiation	The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the nephron tubule as it progresses from its formation to the mature state.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-02-24T02:40:11Z					biological_process											owl:Class	
GO:0035079	biolink:NamedThing	polytene chromosome puffing	The decondensing (loosening) and swelling of the chromosomal sites of target genes on polytene chromosomes following response to a stimulus, to facilitate sudden bursts of transcriptional activity in response to transient environmental signals.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0070903	biolink:NamedThing	mitochondrial tRNA thio-modification	The addition a sulfur atom to a nucleotide in a mitochondrial tRNA molecule.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-09-02T04:11:17Z					biological_process											owl:Class	
GO:0036125	biolink:NamedThing	fatty acid beta-oxidation multienzyme complex	A multienzyme complex possessing three kinds of enzymes that catalyze the chain reactions in the fatty acid beta-oxidation cycle, enoyl-CoA hydratase (ECH), 3-hydroxyacyl-CoA dehydrogenase (HACD), and acetyl-CoA C-acyltransferase (KACT).	tmpzr1t_l9r_go_relaxed.owl						For fatty acid beta-oxidation multienzyme complexes located in the mitochondrial matrix, consider instead the term 'mitochondrial fatty acid beta-oxidation multienzyme complex ; GO:0016507'.		bf	2012-02-28T02:10:39Z					cellular_component											owl:Class	
GO:2000554	biolink:NamedThing	regulation of T-helper 1 cell cytokine production	Any process that modulates the frequency, rate or extent of T-helper 1 cell cytokine production.	tmpzr1t_l9r_go_relaxed.owl	regulation of Th1 cell cytokine production							ebc	2011-04-03T07:35:43Z					biological_process											owl:Class	
GO:0033404	biolink:NamedThing	UUG codon-amino acid adaptor activity	A triplet codon-amino acid adaptor activity that recognizes a UUG codon.	tmpzr1t_l9r_go_relaxed.owl	leucine tRNA|TTG codon-amino acid adaptor activity					Note that in the standard genetic code, TTG codes for leucine.								molecular_function											owl:Class	
GO:1905458	biolink:NamedThing	positive regulation of lymphoid progenitor cell differentiation	Any process that activates or increases the frequency, rate or extent of lymphoid progenitor cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of lymphoid progenitor cell differentiation|activation of lymphoid progenitor cell differentiation|up regulation of lymphoid progenitor cell differentiation|upregulation of lymphoid progenitor cell differentiation							rz	2016-09-16T12:32:55Z					biological_process											owl:Class	
GO:0015767	biolink:NamedThing	lactose transport	The directed movement of lactose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Lactose is a disaccharide 4-O-beta-D-galactopyranosyl-D-glucose, and constitutes roughly 5% of the milk in almost all mammals.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0047479	biolink:NamedThing	trypanothione synthase activity	Catalysis of the reaction: reduced glutathione + glutathionylspermidine + ATP = trypanothione + ADP + phosphate.	tmpzr1t_l9r_go_relaxed.owl	TSR synthetase activity|glutathionylspermidine:glutathione ligase (ADP-forming)				EC:6.3.1.9|MetaCyc:6.3.1.9-RXN|RHEA:21532									molecular_function											owl:Class	
GO:1903723	biolink:NamedThing	negative regulation of centriole elongation	Any process that stops, prevents or reduces the frequency, rate or extent of centriole elongation.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of centriole elongation|down regulation of centriole elongation|inhibition of centriole elongation|downregulation of centriole elongation							als	2014-12-09T16:36:12Z					biological_process											owl:Class	
GO:0050659	biolink:NamedThing	N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity	Catalysis of the reactions: 3'-phosphoadenylyl sulfate + dermatan = adenosine 3',5'-bisphosphate + dermatan 6'-sulfate and 3'-phosphoadenylyl sulfate + chondroitin = adenosine 3',5'-bisphosphate + chondroitin 6'-sulfate.	tmpzr1t_l9r_go_relaxed.owl	3'-phosphoadenylyl-sulfate:dermatan 6'-sulfotransferase activity|N-acetylgalactosamine 4-sulfate 6-O-sulphotransferase activity|GalNAc4S-6ST				KEGG_REACTION:R07288|Reactome:R-HSA-2018659|KEGG_REACTION:R02181|MetaCyc:RXN-7953|EC:2.8.2.33|MetaCyc:RXN-7954	Consider instead annotating to the individual reactions: 'chondroitin 6-sulfotransferase activity ; GO:0008459' and 'dermatan 6-sulfotransferase activity ; GO:0036443'.								molecular_function											owl:Class	
GO:0032442	biolink:NamedThing	phenylcoumaran benzylic ether reductase activity	Catalysis of the NADPH-dependent 7-O-4' reduction of phenylcoumaran lignans to the corresponding diphenols; for example, catalysis of the reaction: dehydrodiconiferyl alcohol + NADPH + H+ = isodihydrodehydrodiconiferyl alcohol + NADP+.	tmpzr1t_l9r_go_relaxed.owl	PCBER activity													molecular_function											owl:Class	
GO:0051496	biolink:NamedThing	positive regulation of stress fiber assembly	Any process that activates or increases the frequency, rate or extent of the assembly of a stress fiber, a bundle of microfilaments and other proteins found in fibroblasts.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of stress fibre formation|positive regulation of stress fibre biosynthesis|up-regulation of stress fiber formation|stimulation of stress fiber formation|activation of stress fiber formation|up regulation of stress fiber formation|upregulation of stress fiber formation													biological_process											owl:Class	
GO:0051492	biolink:NamedThing	regulation of stress fiber assembly	Any process that modulates the frequency, rate or extent of the assembly of a stress fiber, a bundle of microfilaments and other proteins found in fibroblasts.	tmpzr1t_l9r_go_relaxed.owl	regulation of stress fibre biosynthesis|regulation of stress fibre formation													biological_process											owl:Class	
GO:0005747	biolink:NamedThing	mitochondrial respiratory chain complex I	A protein complex located in the mitochondrial inner membrane that forms part of the mitochondrial respiratory chain. It contains about 25 different polypeptide subunits, including NADH dehydrogenase (ubiquinone), flavin mononucleotide and several different iron-sulfur clusters containing non-heme iron. The iron undergoes oxidation-reduction between Fe(II) and Fe(III), and catalyzes proton translocation linked to the oxidation of NADH by ubiquinone.	tmpzr1t_l9r_go_relaxed.owl												GO:0005748		cellular_component											owl:Class	
GO:0046093	biolink:NamedThing	deoxycytidine biosynthetic process	The chemical reactions and pathways resulting in the formation of deoxycytidine, 2-deoxyribosylcytosine, one of the four major nucleosides of DNA.	tmpzr1t_l9r_go_relaxed.owl	deoxycytidine anabolism|deoxycytidine formation|deoxycytidine biosynthesis|deoxycytidine synthesis													biological_process											owl:Class	
GO:1905802	biolink:NamedThing	regulation of cellular response to manganese ion	Any process that modulates the frequency, rate or extent of cellular response to manganese ion.	tmpzr1t_l9r_go_relaxed.owl	regulation of cellular response to manganese							pga	2017-01-11T14:59:39Z					biological_process											owl:Class	
GO:1990558	biolink:NamedThing	mitochondrial malonate(1-) transmembrane transport	The process in which malonate(1-) is transported across a mitochondrial membrane, into or out of the mitochondrion.	tmpzr1t_l9r_go_relaxed.owl								vw	2014-11-19T12:52:43Z					biological_process											owl:Class	
GO:0019720	biolink:NamedThing	Mo-molybdopterin cofactor metabolic process	The chemical reactions and pathways involving the Mo-molybdopterin cofactor, essential for the catalytic activity of some enzymes. The cofactor consists of a mononuclear molybdenum (Mo) ion coordinated by one or two molybdopterin ligands.	tmpzr1t_l9r_go_relaxed.owl	Mo-molybdopterin cofactor metabolism|Moco metabolic process|Moco metabolism													biological_process											owl:Class	
GO:0101018	biolink:NamedThing	negative regulation of mitotic DNA replication initiation from late origin	Any process that stops, prevents or reduces the frequency, rate or extent of firing from a late origin of replication involved in mitotic DNA replication.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of late replication origin firing							mec						biological_process											owl:Class	
GO:0101017	biolink:NamedThing	regulation of mitotic DNA replication initiation from late origin	Any process that modulates the frequency, rate or extent of firing from a late origin of replication involved in mitotic DNA replication.	tmpzr1t_l9r_go_relaxed.owl	regulation of late replication origin firing							mec						biological_process											owl:Class	
GO:0033203	biolink:NamedThing	DNA helicase A complex	A homohexameric protein complex that possesses DNA helicase activity; associates with DNA polymerase alpha-primase and translocates in the 5' to 3' direction.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0043955	biolink:NamedThing	3-hydroxypropionyl-CoA synthetase activity	Catalysis of the reaction: 3-hydroxypropionate + ATP + CoA = 3-hydroxypropionyl-CoA + AMP + diphosphate.	tmpzr1t_l9r_go_relaxed.owl	AMP-dependent synthetase and ligase:Enoyl-CoA hydratase/isomerase|AMP-dependent synthetase and ligase|enoyl-CoA hydratase/isomerase|acetyl-coenzyme A synthetase/GroES-like domain|acetyl-coenzyme A synthetase|3-hydroxy propionyl-CoA synthetase activity				EC:6.2.1.36|RHEA:26534	Note that this function is one of the activities of the trifunctional enzyme propionyl-coenzyme A synthase. See PMID:11821399.								molecular_function											owl:Class	
GO:0010139	biolink:NamedThing	pyrimidine deoxyribonucleotide salvage	The pathway by which pyrimidine bases or pyrimidine deoxyribonucleotides from pyrimidine nucleotide breakdown are converted back to pyrimidine deoxyribonucleotides. The salvage pathway is important where there is no de novo pyrimidine deoxyribonucleotide biosynthesis.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:PWY0-181									biological_process											owl:Class	
GO:0014915	biolink:NamedThing	regulation of muscle filament sliding speed involved in regulation of the velocity of shortening in skeletal muscle contraction	Any process that modulates the velocity of muscle filament sliding, and consequently contributes to the regulation of the velocity of shortening of skeletal muscle contraction.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0019927	biolink:NamedThing	peptide cross-linking via 4'-(S-L-cysteinyl)-L-tryptophyl quinone	The cross-linking of a cysteine residue to tryptophyl quinone to form 4'-(S-L-cysteinyl)-L-tryptophyl quinone, a cofactor found at the active site of amine dehydrogenase.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0313									biological_process											owl:Class	
GO:0110065	biolink:NamedThing	regulation of interphase mitotic telomere clustering	Any process that modulates the frequency, rate or extent of mitotic telomere clustering during interphase.	tmpzr1t_l9r_go_relaxed.owl	regulation of mitotic telomere clustering during interphase							kmv	2017-11-17T22:03:40Z					biological_process											owl:Class	
GO:1901773	biolink:NamedThing	lincomycin catabolic process	The chemical reactions and pathways resulting in the breakdown of lincomycin.	tmpzr1t_l9r_go_relaxed.owl	lincomycin breakdown|lincomycin degradation|lincomycin catabolism							yaf	2013-01-15T11:53:57Z					biological_process											owl:Class	
GO:0090542	biolink:NamedThing	ELYC domain binding	Binding to a ELYC protein domain. The ELYC domain is an approximately 150 amino acid sequence which contains a highly conserved tetrapeptide sequence, ELYC.	tmpzr1t_l9r_go_relaxed.owl								tb	2013-02-14T17:11:29Z					molecular_function											owl:Class	
GO:1905242	biolink:NamedThing	response to 3,3',5-triiodo-L-thyronine	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 3,3',5-triiodo-L-thyronine stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to Liothyronine|response to Liothyronin|response to Liothyroninum							sl	2016-06-08T17:42:04Z					biological_process											owl:Class	
GO:1905813	biolink:NamedThing	negative regulation of motor neuron axon guidance	Any process that stops, prevents or reduces the frequency, rate or extent of motor neuron axon guidance.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of motor neuron axon guidance|down regulation of motor axon guidance|downregulation of motor axon pathfinding|negative regulation of motor axon guidance|down regulation of motor neuron axon guidance|down regulation of motoneuron axon guidance|inhibition of motor neuron axon guidance|inhibition of motoneuron axon guidance|down-regulation of motoneuron axon guidance|downregulation of motoneuron axon guidance|inhibition of motor axon guidance|inhibition of motor axon pathfinding|negative regulation of motoneuron axon guidance|down regulation of motor axon pathfinding|downregulation of motor neuron axon guidance|negative regulation of motor axon pathfinding|downregulation of motor axon guidance|down-regulation of motor axon pathfinding|down-regulation of motor axon guidance							hbye	2017-01-12T13:25:21Z					biological_process											owl:Class	
GO:0017177	biolink:NamedThing	glucosidase II complex	A heterodimeric complex that catalyzes the trimming of glucose residues from N-linked core glycans on newly synthesized glycoproteins.	tmpzr1t_l9r_go_relaxed.owl	alpha-glucosidase II complex					Note that alpha-glucosidase I functions as a monomer, and therefore does not have a corresponding cellular component term.								cellular_component											owl:Class	
GO:1900030	biolink:NamedThing	regulation of pectin biosynthetic process	Any process that modulates the frequency, rate or extent of pectin biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of pectin anabolism|regulation of pectin biosynthesis|regulation of pectin synthesis|regulation of pectin formation							tb	2012-01-13T02:03:37Z					biological_process											owl:Class	
GO:0071240	biolink:NamedThing	cellular response to food	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a food stimulus; food is anything which, when taken into the body, serves to nourish or build up the tissues or to supply body heat.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-12-03T02:28:35Z					biological_process											owl:Class	
GO:0051059	biolink:NamedThing	NF-kappaB binding	Binding to NF-kappaB, a transcription factor for eukaryotic RNA polymerase II promoters.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0045997	biolink:NamedThing	negative regulation of ecdysteroid biosynthetic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of ecdysteroids.	tmpzr1t_l9r_go_relaxed.owl	down regulation of ecdysteroid biosynthetic process|inhibition of ecdysteroid biosynthetic process|negative regulation of ecdysteroid anabolism|down-regulation of ecdysteroid biosynthetic process|negative regulation of ecdysteroid formation|downregulation of ecdysteroid biosynthetic process|negative regulation of ecdysteroid synthesis|negative regulation of ecdysteroid biosynthesis													biological_process											owl:Class	
GO:0009828	biolink:NamedThing	plant-type cell wall loosening	The series of events causing chemical and structural alterations of an existing cellulose and pectin-containing cell wall that results in greater extensibility of the wall. An example of this is found in Arabidopsis thaliana.	tmpzr1t_l9r_go_relaxed.owl	cellulose and pectin-containing cell wall loosening													biological_process											owl:Class	
GO:0045163	biolink:NamedThing	clustering of voltage-gated potassium channels	The process in which voltage-gated potassium channels become localized together in high densities. In animals, voltage-gated potassium (Kv) channels are clustered beneath the myelin sheath in regions immediately adjacent to paranodes, called juxtaparanodes, and along the inner mesaxon within the internode.	tmpzr1t_l9r_go_relaxed.owl	Kv channel clustering|clustering of voltage gated potassium channels|voltage-gated potassium channel clustering|clustering of voltage-dependent potassium channels													biological_process											owl:Class	
GO:0042907	biolink:NamedThing	xanthine transmembrane transporter activity	Enables the transfer of xanthine from one side of a membrane to the other. Xanthine (2,6-dihydroxypurine) is a purine formed in the metabolic breakdown of guanine, but is not present in nucleic acids.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0032919	biolink:NamedThing	spermine acetylation	The modification of spermine by addition of acetyl groups.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1901531	biolink:NamedThing	hypochlorite binding	Binding to hypochlorite.	tmpzr1t_l9r_go_relaxed.owl								pr	2012-10-24T07:15:22Z					molecular_function											owl:Class	
GO:1903089	biolink:NamedThing	5-amino-1-ribofuranosylimidazole-4-carboxamide transmembrane transporter activity	Enables the transfer of 5-amino-1-ribofuranosylimidazole-4-carboxamide from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	acadesine transporter activity							mcc	2014-06-02T20:37:17Z					molecular_function											owl:Class	
GO:0003414	biolink:NamedThing	chondrocyte morphogenesis involved in endochondral bone morphogenesis	The process in which the structures of a chondrocyte that will contribute to bone development are generated and organized.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-12-22T08:42:55Z					biological_process											owl:Class	
GO:1990018	biolink:NamedThing	tail portion of tanycyte	Elongated process of a tanycyte, devoid of cytoplasmic extensions, that courses through the hypothalamic nuclei to form small endfoot processes that terminate either on blood vessels or at the pial surface of the brain. A tanycyte is a specialized elongated ventricular ependymal cell.	tmpzr1t_l9r_go_relaxed.owl	tail portion				NIF_Subcellular:sao1749953771			pr	2012-12-19T15:21:20Z					cellular_component											owl:Class	
GO:0045309	biolink:NamedThing	protein phosphorylated amino acid binding	Binding to a phosphorylated amino acid residue within a protein.	tmpzr1t_l9r_go_relaxed.owl	phosphoprotein amino acid binding													molecular_function											owl:Class	
GO:0051219	biolink:NamedThing	phosphoprotein binding	Binding to a phosphorylated protein.	tmpzr1t_l9r_go_relaxed.owl	phosphorylated protein binding													molecular_function											owl:Class	
GO:0019286	biolink:NamedThing	glycine betaine biosynthetic process from glycine	The chemical reactions and pathways resulting in the formation of glycine betaine from other compounds, including glycine.	tmpzr1t_l9r_go_relaxed.owl	glycine betaine anabolism from glycine|glycine betaine synthesis from glycine|N-trimethylglycine biosynthetic process from glycine|N-trimethylglycine biosynthesis from glycine|glycine betaine formation from glycine				MetaCyc:P541-PWY									biological_process											owl:Class	
GO:0120188	biolink:NamedThing	regulation of bile acid secretion	Any process that modulates the frequency, rate or extent of the controlled release of bile acid from a cell or a tissue.	tmpzr1t_l9r_go_relaxed.owl								krc	2018-07-16T22:28:58Z					biological_process											owl:Class	
GO:0002019	biolink:NamedThing	regulation of renal output by angiotensin	The process in which angiotensin directly modulates the rate of urine output by the kidney.	tmpzr1t_l9r_go_relaxed.owl	angiotensin mediated control of renal output|angiotensin-mediated regulation of renal output|angiotensin mediated regulation of renal output													biological_process											owl:Class	
GO:0015474	biolink:NamedThing	autotransporter activity	Transports a passenger protein from the periplasm to the external milieu; the passenger protein and the porin are the N- and C-terminal regions of the same protein, respectively.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0035795	biolink:NamedThing	negative regulation of mitochondrial membrane permeability	Any process that decreases the frequency, rate or extent of the passage or uptake of molecules by the mitochondrial membrane.	tmpzr1t_l9r_go_relaxed.owl	mitochondrial membrane impermeabilization|mitochondrial membrane impermeability|negative regulation of transport across mitochondrial membrane							bf	2011-04-11T01:45:26Z					biological_process											owl:Class	
GO:1901835	biolink:NamedThing	positive regulation of deadenylation-independent decapping of nuclear-transcribed mRNA	Any process that activates or increases the frequency, rate or extent of deadenylation-independent decapping of nuclear-transcribed mRNA.	tmpzr1t_l9r_go_relaxed.owl	activation of deadenylation-independent decapping of nuclear mRNA|up regulation of deadenylylation-independent decapping|up regulation of deadenylation-independent decapping of nuclear-transcribed mRNA|up regulation of deadenylation-independent decapping of nuclear mRNA|upregulation of deadenylation-independent decapping of nuclear-transcribed mRNA|upregulation of deadenylylation-independent decapping|activation of deadenylylation-independent decapping|activation of deadenylation-independent decapping of nuclear-transcribed mRNA|upregulation of deadenylation-independent decapping of nuclear mRNA|up-regulation of deadenylation-independent decapping of nuclear mRNA|positive regulation of deadenylylation-independent decapping|positive regulation of deadenylation-independent decapping of nuclear mRNA|up-regulation of deadenylylation-independent decapping|up-regulation of deadenylation-independent decapping of nuclear-transcribed mRNA							al	2013-01-22T22:42:22Z					biological_process											owl:Class	
GO:0009674	biolink:NamedThing	potassium:sodium symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: K+(out) + Na+(out) = K+(in) + Na+(in).	tmpzr1t_l9r_go_relaxed.owl	high affinity potassium transporter													molecular_function											owl:Class	
GO:0036185	biolink:NamedThing	13-lipoxin reductase activity	Definition: Catalysis of the reaction: 15-oxolipoxin A4 + NAD(P)H + H+ = 13,14-dihydro-15-oxolipoxin A4 + NAD(P)+.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-2161844			bf	2012-04-16T02:28:19Z					molecular_function											owl:Class	
GO:1903658	biolink:NamedThing	positive regulation of type IV pilus biogenesis	Any process that activates or increases the frequency, rate or extent of type IV pilus biogenesis.	tmpzr1t_l9r_go_relaxed.owl	activation of type IV fimbrial biogenesis|up regulation of type IV fimbrial assembly|up-regulation of type IV pilus biogenesis|up regulation of type IV fimbrium biogenesis|upregulation of type IV fimbria assembly|up-regulation of type IV fimbriae assembly|up-regulation of TFP biogenesis|positive regulation of type IV fimbria biogenesis|upregulation of type IV fimbrium biogenesis|positive regulation of type IV fimbriae assembly|up-regulation of type IV pilus biosynthesis|up regulation of type IV fimbrium assembly|positive regulation of type 4 pilus biogenesis|up regulation of type IV fimbria biogenesis|up-regulation of type IV fimbrium biogenesis|upregulation of type 4 pilus biogenesis|positive regulation of type IV fimbrial assembly|activation of type IV fimbria biogenesis|up-regulation of type IV fimbria assembly|up-regulation of type IV fimbrium assembly|activation of type IV fimbriae biogenesis|upregulation of type IV pilus biosynthesis|activation of TFP biogenesis|upregulation of type IV fimbrial biogenesis|activation of type IV pilus biosynthesis|activation of type IV pilus biogenesis|activation of type IV fimbrium assembly|upregulation of type IV fimbriae biogenesis|positive regulation of type IV fimbrium assembly|upregulation of type IV fimbria biogenesis|up regulation of type IV pilus biogenesis|upregulation of type IV pilus biogenesis|up regulation of type IV fimbrial biogenesis|positive regulation of type IV fimbrial biogenesis|up-regulation of type IV fimbrial biogenesis|activation of type IV fimbrial assembly|upregulation of type IV fimbriae assembly|positive regulation of type IV fimbrium biogenesis|up regulation of TFP biogenesis|up-regulation of type IV fimbrial assembly|upregulation of type IV fimbrium assembly|upregulation of type IV fimbrial assembly|positive regulation of TFP biogenesis|activation of type IV fimbriae assembly|upregulation of TFP biogenesis|activation of type IV fimbria assembly|positive regulation of type IV pilus biosynthesis|positive regulation of type IV fimbriae biogenesis|up-regulation of type IV fimbriae biogenesis|up regulation of type 4 pilus biogenesis|up regulation of type IV pilus biosynthesis|activation of type IV fimbrium biogenesis|up regulation of type IV fimbriae assembly|activation of type 4 pilus biogenesis|up regulation of type IV fimbria assembly|positive regulation of type IV fimbria assembly|up-regulation of type 4 pilus biogenesis|up regulation of type IV fimbriae biogenesis|up-regulation of type IV fimbria biogenesis							jl	2014-11-25T12:03:34Z					biological_process											owl:Class	
GO:0072320	biolink:NamedThing	volume-sensitive chloride channel activity	Enables the transmembrane transfer of a chloride ion by a volume-sensitive channel. A volume-sensitive channel is a channel that responds to changes in the volume of a cell.	tmpzr1t_l9r_go_relaxed.owl	swell-activated chloride channel							mah	2010-10-26T12:53:38Z					molecular_function											owl:Class	
GO:0005225	biolink:NamedThing	volume-sensitive anion channel activity	Enables the transmembrane transfer of an anion by a volume-sensitive channel. An anion is a negatively charged ion. A volume-sensitive channel is a channel that responds to changes in the volume of a cell.	tmpzr1t_l9r_go_relaxed.owl	volume-regulated channel				Reactome:R-HSA-8941543									molecular_function											owl:Class	
GO:1905374	biolink:NamedThing	response to homocysteine	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a homocysteine stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to 2-amino-4-sulfanylbutanoic acid|response to Hcy|response to 2-amino-4-mercaptobutyric acid							sl	2016-08-17T20:17:53Z					biological_process											owl:Class	
GO:0060948	biolink:NamedThing	cardiac vascular smooth muscle cell development	The process whose specific outcome is the progression of a cardiac vascular smooth muscle cell over time, from its formation to the mature state.	tmpzr1t_l9r_go_relaxed.owl	heart vascular smooth muscle cell development							dph	2009-09-29T03:00:24Z					biological_process											owl:Class	
GO:0052800	biolink:NamedThing	bicyclic nitroimidazole catabolic process	The chemical reactions and pathways resulting in the breakdown of a bicyclic nitroimidazole.	tmpzr1t_l9r_go_relaxed.owl	bicyclic nitroimidazole catabolism|bicyclic nitroimidazole degradation|bicyclic nitroimidazole breakdown													biological_process											owl:Class	
GO:1905025	biolink:NamedThing	negative regulation of membrane repolarization during ventricular cardiac muscle cell action potential	Any process that stops, prevents or reduces the frequency, rate or extent of membrane repolarization during ventricular cardiac muscle cell action potential.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of regulation of ventricular cardiac muscle repolarization|down regulation of regulation of ventricular cardiac muscle repolarization|downregulation of electrocardiogram T wave|down regulation of ventricular repolarization|negative regulation of electrocardiogram T wave|inhibition of electrocardiogram T wave|inhibition of regulation of ventricular cardiac muscle repolarization|negative regulation of ventricular repolarization|down regulation of membrane repolarization during ventricular cardiac muscle cell action potential|down-regulation of electrocardiogram T wave|down-regulation of ventricular repolarization|inhibition of membrane repolarization during ventricular cardiac muscle cell action potential|down regulation of electrocardiogram T wave|downregulation of ventricular repolarization|negative regulation of regulation of ventricular cardiac muscle repolarization|down-regulation of membrane repolarization during ventricular cardiac muscle cell action potential|downregulation of regulation of ventricular cardiac muscle repolarization|inhibition of ventricular repolarization|downregulation of membrane repolarization during ventricular cardiac muscle cell action potential							rph	2016-03-04T11:19:12Z					biological_process											owl:Class	
GO:0007133	biolink:NamedThing	meiotic anaphase I	The cell cycle phase during which chromosomes separate and migrate towards the poles of the spindle the as part of meiosis I.	tmpzr1t_l9r_go_relaxed.owl						Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).								biological_process											owl:Class	
GO:0034346	biolink:NamedThing	positive regulation of type III interferon production	Any process that activates or increases the frequency, rate, or extent of type III interferon production. Interferon lambda is the only member of the type III interferon found so far.	tmpzr1t_l9r_go_relaxed.owl	activation of type III interferon production|stimulation of type III interferon production|upregulation of type III interferon production|up-regulation of type III interferon production|up regulation of type III interferon production|positive regulation of type III IFN production					Note that IL-28A, IL-28B, and IL-29 are types of interferon-lambda.								biological_process											owl:Class	
GO:0016404	biolink:NamedThing	15-hydroxyprostaglandin dehydrogenase (NAD+) activity	Catalysis of the reaction: (5Z,13E)-(15S)-11-alpha,15-dihydroxy-9-oxoprost-13-enoate + NAD+ = (5Z,13E)-11-alpha-hydroxy-9,15-dioxoprost-13-enoate + NADH + H+.	tmpzr1t_l9r_go_relaxed.owl	(5Z,13E)-(15S)-11alpha,15-dihydroxy-9-oxoprost-13-enoate:NAD+ 15-oxidoreductase activity|15-hydroxyprostanoic dehydrogenase activity|15-hydroxyprostaglandin dehydrogenase activity|prostaglandin dehydrogenase activity|NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (type I)|NAD-specific 15-hydroxyprostaglandin dehydrogenase activity|15-OH-PGDH|11alpha,15-dihydroxy-9-oxoprost-13-enoate:NAD+ 15-oxidoreductase activity				MetaCyc:1.1.1.141-RXN|Reactome:R-HSA-9024766|Reactome:R-HSA-2161779|Reactome:R-HSA-9023968|Reactome:R-HSA-2161662|EC:1.1.1.141|RHEA:11876									molecular_function											owl:Class	
GO:0061410	biolink:NamedThing	positive regulation of transcription from RNA polymerase II promoter in response to ethanol	Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of an ethanol stimulus.	tmpzr1t_l9r_go_relaxed.owl								dph	2012-01-12T12:17:35Z					biological_process											owl:Class	
GO:0035347	biolink:NamedThing	negative regulation of hypoxanthine transport	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of hypoxanthine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of 6-hydroxypurine transport							bf	2010-03-04T10:43:53Z					biological_process											owl:Class	
GO:0035345	biolink:NamedThing	regulation of hypoxanthine transport	Any process that modulates the frequency, rate or extent of the directed movement of hypoxanthine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	regulation of 6-hydroxypurine transport							bf	2010-03-04T10:42:04Z					biological_process											owl:Class	
GO:0034520	biolink:NamedThing	2-naphthaldehyde dehydrogenase activity	Catalysis of the reaction: 2-naphthaldehyde + NAD+ + H2O = 2-naphthoate + NADH + H+.	tmpzr1t_l9r_go_relaxed.owl					EC:1.2.1.-|UM-BBD_reactionID:r0772									molecular_function											owl:Class	
GO:0019485	biolink:NamedThing	beta-alanine catabolic process to L-alanine	The chemical reactions and pathways resulting in the breakdown of beta-alanine into other compounds, including L-alanine.	tmpzr1t_l9r_go_relaxed.owl	beta-alanine breakdown to L-alanine|beta-alanine degradation to L-alanine													biological_process											owl:Class	
GO:0050435	biolink:NamedThing	amyloid-beta metabolic process	The chemical reactions and pathways involving amyloid-beta, a glycoprotein associated with Alzheimer's disease, and its precursor, amyloid precursor protein (APP).	tmpzr1t_l9r_go_relaxed.owl	amyloid-beta metabolism|beta-amyloid metabolism|beta-amyloid metabolic process													biological_process											owl:Class	
GO:0072058	biolink:NamedThing	outer stripe development	The process whose specific outcome is the progression of the outer stripe over time, from its formation to the mature structure. The outer stripe is the region of the kidney outer medulla that lies just below the cortex. The proximal straight tubules (S3) characterize this region.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-01-25T04:02:56Z					biological_process											owl:Class	
GO:0048852	biolink:NamedThing	diencephalon morphogenesis	The process in which the anatomical structures of the diencephalon are generated and organized. The diencephalon is the paired caudal parts of the prosencephalon from which the thalamus, hypothalamus, epithalamus and subthalamus are derived; these regions regulate autonomic, visceral and endocrine function, and process information directed to the cerebral cortex.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0072163	biolink:NamedThing	mesonephric epithelium development	The process whose specific outcome is the progression of an epithelium in the mesonephros over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-02-26T01:40:43Z					biological_process											owl:Class	
GO:0072073	biolink:NamedThing	kidney epithelium development	The process whose specific outcome is the progression of an epithelium in the kidney over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-01-25T04:37:42Z					biological_process											owl:Class	
GO:0032180	biolink:NamedThing	ubiquinone biosynthetic process from tyrosine	The chemical reactions and pathways resulting in the formation of ubiquinone, beginning with the conversion of tyrosine to 4-hydroxybenzoate.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1902406	biolink:NamedThing	mitotic actomyosin contractile ring maintenance	Any actomyosin contractile ring maintenance that is involved in mitotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl	cytokinesis, contractile ring maintenance, involved in cytokinesis during cell cycle involved in mitotic cell cycle|contractile ring maintenance involved in cell cycle cytokinesis involved in mitotic cell cycle							jl	2013-09-12T12:28:14Z					biological_process											owl:Class	
GO:0050676	biolink:NamedThing	negative regulation of urothelial cell proliferation	Any process that stops, prevents or reduces the rate or extent of urothelial cell proliferation.	tmpzr1t_l9r_go_relaxed.owl	downregulation of urothelial cell proliferation|inhibition of urothelial cell proliferation|down-regulation of urothelial cell proliferation|down regulation of urothelial cell proliferation													biological_process											owl:Class	
GO:0050675	biolink:NamedThing	regulation of urothelial cell proliferation	Any process that modulates the frequency, rate or extent of urothelial cell proliferation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0034426	biolink:NamedThing	etioplast membrane	Either of the lipid bilayers that surround a etioplast and form the etioplast envelope.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0042870	biolink:NamedThing	D-glucarate transmembrane transport	The process in which D-glucarate, the D-enantiomer of glucarate, is transported across a lipid bilayer, from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	D-glucarate transport													biological_process											owl:Class	
GO:1900742	biolink:NamedThing	negative regulation of filamentous growth of a population of unicellular organisms in response to pH	Any process that stops, prevents or reduces the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to pH.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of filamentous growth of a population of unicellular organisms in response to pH|down regulation of filamentous growth of a population of unicellular organisms in response to pH|downregulation of filamentous growth of a population of unicellular organisms in response to pH|inhibition of filamentous growth of a population of unicellular organisms in response to pH							di	2012-05-28T02:35:03Z					biological_process											owl:Class	
GO:0090584	biolink:NamedThing	protein-phosphocysteine-galactitol-phosphotransferase system transporter activity	Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein S-phosphocysteine + galactitol(out) = protein cysteine + galactitol-6-phosphate(in).	tmpzr1t_l9r_go_relaxed.owl								tb	2014-06-04T16:22:31Z					molecular_function											owl:Class	
GO:0070646	biolink:NamedThing	protein modification by small protein removal	A protein modification process in which one or more covalently attached groups of a small protein, such as ubiquitin or a ubiquitin-like protein, are removed from a target protein.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-05-11T01:58:15Z					biological_process											owl:Class	
GO:0004996	biolink:NamedThing	thyroid-stimulating hormone receptor activity	Combining with thyroid-stimulating hormone to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	thyroid stimulating hormone receptor activity|TSH receptor activity|thyrotropin receptor				Wikipedia:Thyrotropin_receptor									molecular_function											owl:Class	
GO:1990254	biolink:NamedThing	keratin filament binding	Binding to a keratin filament, an intermediate filament composed of acidic and basic keratins (types I and II), typically expressed in epithelial cells.	tmpzr1t_l9r_go_relaxed.owl								tb	2013-12-13T22:05:25Z					molecular_function											owl:Class	
GO:0019215	biolink:NamedThing	intermediate filament binding	Binding to an intermediate filament, a distinct elongated structure, characteristically 10 nm in diameter, that occurs in the cytoplasm of higher eukaryotic cells. Intermediate filaments form a fibrous system, composed of chemically heterogeneous subunits and involved in mechanically integrating the various components of the cytoplasmic space.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0070441	biolink:NamedThing	G-protein beta/gamma-Btk complex	A protein complex formed by the association of the Bruton tyrosine protein kinase Btk, which is implicated in mammalian X-linked immunodeficiencies, with the beta and gamma subunits of a heterotrimeric G protein.	tmpzr1t_l9r_go_relaxed.owl	G protein complex (BTK, GNG1, GNG2)|G protein complex (Btk, Gng2, Gnb1)					See also the cellular component term 'heterotrimeric G-protein complex ; GO:0005834'.								cellular_component											owl:Class	
GO:0032849	biolink:NamedThing	positive regulation of cellular pH reduction	Any process that activates or increases the frequency, rate, or extent of a process that reduces the internal pH of a cell.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of cell pH reduction|positive regulation of cellular acidification|positive regulation of intracellular pH reduction|activation of cellular pH reduction|positive regulation of reduction of cellular pH|upregulation of cellular pH reduction|positive regulation of reduction of pH in cell|stimulation of cellular pH reduction|positive regulation of intracellular acidification|up regulation of cellular pH reduction|up-regulation of cellular pH reduction													biological_process											owl:Class	
GO:0052028	biolink:NamedThing	induction by symbiont of host signal transduction pathway	Any process in which an organism activates, maintains or increases the frequency, rate or extent of the host signal transduction pathways, the cascade of processes by which a signal interacts with a receptor. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	stimulation by symbiont of host signal transduction pathway|positive regulation by symbiont of host signal transduction pathway|positive regulation of signal transduction in other organism|activation by symbiont of host signal transduction pathway|upregulation by symbiont of host signal transduction pathway|up regulation by symbiont of host signal transduction pathway|positive regulation by organism of signal transduction in other organism involved in symbiotic interaction|up-regulation by symbiont of host signal transduction pathway											GO:0052526|GO:0044502		biological_process											owl:Class	
GO:0015790	biolink:NamedThing	UDP-xylose transmembrane transport	The directed movement of UDP-xylose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. UDP-xylose is a substance composed of xylose in glycosidic linkage with uridine diphosphate.	tmpzr1t_l9r_go_relaxed.owl	UDP-xylose transport													biological_process											owl:Class	
GO:0032326	biolink:NamedThing	Mo-molybdopterin cofactor catabolic process	The chemical reactions and pathways resulting in the breakdown of the Mo-molybdopterin cofactor, essential for the catalytic activity of some enzymes. The cofactor consists of a mononuclear molybdenum (Mo) ion coordinated by one or two molybdopterin ligands.	tmpzr1t_l9r_go_relaxed.owl	Moco catabolism|Mo-molybdopterin cofactor catabolism|Mo-molybdopterin cofactor degradation|Mo-molybdopterin cofactor breakdown|Moco catabolic process													biological_process											owl:Class	
GO:0050307	biolink:NamedThing	sucrose-phosphate phosphatase activity	Catalysis of the reaction: sucrose 6F-phosphate + H2O = sucrose + phosphate.	tmpzr1t_l9r_go_relaxed.owl	sucrose-phosphate phosphohydrolase activity|sucrose-6F-phosphate phosphohydrolase activity				EC:3.1.3.24|MetaCyc:SUCROSE-PHOSPHATASE-RXN|KEGG_REACTION:R06211|KEGG_REACTION:R00805|RHEA:19289									molecular_function											owl:Class	
GO:0080022	biolink:NamedThing	primary root development	The process whose specific outcome is the progression of the primary root over time, from its formation to the mature structure. The primary root develops directly from the embryonic radicle.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:2000439	biolink:NamedThing	positive regulation of monocyte extravasation	Any process that activates or increases the frequency, rate or extent of monocyte extravasation.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-03-04T10:25:11Z					biological_process											owl:Class	
GO:0060399	biolink:NamedThing	positive regulation of growth hormone receptor signaling pathway	Any process that increases the rate, frequency or extent of the growth hormone receptor signaling pathway. The growth hormone receptor signaling pathway is the series of molecular signals generated as a consequence of growth hormone receptor binding to its physiological ligand.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of growth hormone receptor signalling pathway													biological_process											owl:Class	
GO:0060989	biolink:NamedThing	lipid tube assembly involved in organelle fusion	The aggregation, arrangement and bonding together of a set of macromolecules to form a macromolecular complex that contains a tube of lipid surrounded by a protein coat involved in membrane shaping of vesicle membranes as organelles fuse.	tmpzr1t_l9r_go_relaxed.owl	lipid tubulation involved in organelle fusion							dph	2010-01-11T02:06:50Z					biological_process											owl:Class	
GO:1902940	biolink:NamedThing	positive regulation of intracellular calcium activated chloride channel activity	Any process that activates or increases the frequency, rate or extent of intracellular calcium activated chloride channel activity.	tmpzr1t_l9r_go_relaxed.owl	upregulation of intracellular calcium activated chloride channel activity|up-regulation of intracellular calcium activated chloride channel activity|activation of intracellular calcium activated chloride channel activity|up regulation of intracellular calcium activated chloride channel activity							als	2014-04-28T08:49:20Z					biological_process											owl:Class	
GO:0019568	biolink:NamedThing	arabinose catabolic process	The chemical reactions and pathways resulting in the breakdown of arabinose, arabino-pentose.	tmpzr1t_l9r_go_relaxed.owl	arabinose catabolism|arabinose degradation|arabinose breakdown													biological_process											owl:Class	
GO:0060075	biolink:NamedThing	regulation of resting membrane potential	Any process that modulates the establishment or extent of a resting potential, the electrical charge across the plasma membrane, with the interior of the cell negative with respect to the exterior. The resting potential is the membrane potential of a cell that is not stimulated to be depolarized or hyperpolarized.	tmpzr1t_l9r_go_relaxed.owl	regulation of resting potential													biological_process											owl:Class	
GO:0044715	biolink:NamedThing	8-oxo-dGDP phosphatase activity	Catalysis of the reaction 8-oxo-dGDP + H2O = 8-oxo-dGMP + phosphate.	tmpzr1t_l9r_go_relaxed.owl					RHEA:32063|Reactome:R-HSA-2395879|Reactome:R-HSA-2395873|EC:3.6.1.58			jl	2012-10-18T13:31:09Z					molecular_function											owl:Class	
GO:0120092	biolink:NamedThing	crotonyl-CoA hydratase activity	Catalysis of the reaction: Acetyl-CoA + [protein]-L-lysine = CoA + [protein]-N(6)-acetyl-L-lysine.	tmpzr1t_l9r_go_relaxed.owl					RHEA:45584			krc	2017-08-22T20:13:55Z					molecular_function											owl:Class	
GO:0010041	biolink:NamedThing	response to iron(III) ion	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iron(III) ion stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to iron(III)													biological_process											owl:Class	
GO:0039633	biolink:NamedThing	killing by virus of host cell	Any process mediated by a virus that results in the death of a cell in the host organism.	tmpzr1t_l9r_go_relaxed.owl	killing by virus of host cells|killing by phage of host cells							bf	2012-08-10T14:44:40Z					biological_process											owl:Class	
GO:0010612	biolink:NamedThing	regulation of cardiac muscle adaptation	Any process that modulates the rate, extent or frequency of the process in which cardiac muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0007407	biolink:NamedThing	neuroblast activation	A change in the morphology or behavior of a neuroblast resulting from exposure to an activating factor such as a cellular or soluble ligand.	tmpzr1t_l9r_go_relaxed.owl												GO:0043351|GO:0043352		biological_process											owl:Class	
GO:0070886	biolink:NamedThing	positive regulation of calcineurin-NFAT signaling cascade	Any process that activates or increases the frequency, rate or extent of signaling via the calcineurin-NFAT signaling cascade.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of NFAT protein import into nucleus|activation of calcineurin-NFAT signaling cascade|up-regulation of calcineurin-NFAT signaling cascade|upregulation of calcineurin-NFAT signaling cascade|positive regulation of calcineurin-NFAT signaling pathway|stimulation of calcineurin-NFAT signaling cascade|up regulation of calcineurin-NFAT signaling cascade|positive regulation of calcineurin-NFAT signalling cascade							mah	2009-08-26T03:37:10Z			GO:0051533		biological_process											owl:Class	
GO:0002564	biolink:NamedThing	alternate splicing of immunoglobulin genes	The generation of alternate transcripts of immunoglobulin genes through alternate splicing of exons.	tmpzr1t_l9r_go_relaxed.owl	alternate splicing of antibody genes													biological_process											owl:Class	
GO:0019135	biolink:NamedThing	deoxyhypusine monooxygenase activity	Catalysis of the reaction: protein N6-(4-aminobutyl)-L-lysine + donor-H2 + O2 = protein N6-((R)-4-amino-2-hydroxybutyl)-L-lysine + acceptor + H2O.	tmpzr1t_l9r_go_relaxed.owl	deoxyhypusine dioxygenase activity|DOHH activity|deoxyhypusine,hydrogen-donor:oxygen oxidoreductase (2-hydroxylating)|deoxyhypusine hydroxylase activity				RHEA:14101|Reactome:R-HSA-204662|MetaCyc:DEOXYHYPUSINE-MONOOXYGENASE-RXN|EC:1.14.99.29									molecular_function											owl:Class	
GO:0043546	biolink:NamedThing	molybdopterin cofactor binding	Binding to a molybdopterin cofactor (Moco), essential for the catalytic activity of some enzymes, e.g. sulfite oxidase, xanthine dehydrogenase, and aldehyde oxidase. The cofactor consists of a mononuclear molybdenum (Mo-molybdopterin) or tungsten ion (W-molybdopterin) coordinated by one or two molybdopterin ligands.	tmpzr1t_l9r_go_relaxed.owl	Moco binding													molecular_function											owl:Class	
GO:0048920	biolink:NamedThing	posterior lateral line neuromast primordium migration	The migration of a relatively undifferentiated cell along the developing posterior lateral line, originating from cranial ectodermal placodes situated behind the ear. The neuromast primordium deposits proneuromasts along the lateral line, from which the neuromasts will develop.	tmpzr1t_l9r_go_relaxed.owl	PLL neuromast primordium migration													biological_process											owl:Class	
GO:0048883	biolink:NamedThing	neuromast primordium migration	The migration of a cluster of a relatively undifferentiated cell originating at specific cephalic placodes and depositing proneuromasts along a developing lateral line, from which the neuromasts will develop.	tmpzr1t_l9r_go_relaxed.owl	lateral line primordium migration													biological_process											owl:Class	
GO:0071495	biolink:NamedThing	cellular response to endogenous stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus arising within the organism.	tmpzr1t_l9r_go_relaxed.owl						Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.		mah	2009-12-18T02:25:40Z					biological_process											owl:Class	
GO:0023027	biolink:NamedThing	MHC class I protein binding, via antigen binding groove	Binding to a major histocompatibility complex class I molecules via the antigen binding groove.	tmpzr1t_l9r_go_relaxed.owl									2010-02-16T09:30:50Z					molecular_function											owl:Class	
GO:0018643	biolink:NamedThing	carbon disulfide oxygenase activity	Catalysis of the reaction: carbon disulfide + NADH + H+ + O2 = [S] + H2O + NAD+ + carbonyl sulfide.	tmpzr1t_l9r_go_relaxed.owl	carbon disulphide oxygenase activity				UM-BBD_reactionID:r0599|EC:1.14.13.-									molecular_function											owl:Class	
GO:0043950	biolink:NamedThing	positive regulation of cAMP-mediated signaling	Any process which activates, maintains or increases the frequency, rate or extent of cAMP-mediated signaling, a series of molecular signals in which a cell uses cyclic AMP to convert an extracellular signal into a response.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of cAMP-mediated signalling													biological_process											owl:Class	
GO:0018891	biolink:NamedThing	cyclohexanol metabolic process	The chemical reactions and pathways involving cyclohexanol, the monohydroxy derivative of cyclohexane. It is used as a solvent and blending agent.	tmpzr1t_l9r_go_relaxed.owl	cyclohexanol metabolism				UM-BBD_pathwayID:chx									biological_process											owl:Class	
GO:0043151	biolink:NamedThing	DNA synthesis involved in double-strand break repair via single-strand annealing	The synthesis of DNA that contributes to the process of double-strand break repair via single-strand annealing.	tmpzr1t_l9r_go_relaxed.owl	DNA synthesis during double-strand break repair via single-strand annealing													biological_process											owl:Class	
GO:0047348	biolink:NamedThing	glycerol-3-phosphate cytidylyltransferase activity	Catalysis of the reaction: sn-glycerol 3-phosphate + CTP = CDP-glycerol + diphosphate.	tmpzr1t_l9r_go_relaxed.owl	CTP:glycerol-3-phosphate cytidylyltransferase activity|CTP:sn-glycerol-3-phosphate cytidylyltransferase activity|cytidine diphosphoglycerol pyrophosphorylase activity|CDP-glycerol diphosphorylase activity|cytidine diphosphate glycerol pyrophosphorylase activity|CDP-glycerol pyrophosphorylase activity|Gro-PCT|CTP:glycerol 3-phosphate cytidylyltransferase activity				KEGG_REACTION:R00856|MetaCyc:2.7.7.39-RXN|RHEA:13361|EC:2.7.7.39									molecular_function											owl:Class	
GO:0018868	biolink:NamedThing	2-aminobenzenesulfonate metabolic process	The chemical reactions and pathways involving 2-aminobenzenesulfonate, aniline-o-sulfonic acid, an aromatic sulfonate used in organic synthesis and in the manufacture of various dyes and medicines.	tmpzr1t_l9r_go_relaxed.owl	2-aminobenzenesulphonate metabolic process|2-aminobenzenesulfonate metabolism|2-aminobenzenesulphonate metabolism				UM-BBD_pathwayID:abs									biological_process											owl:Class	
GO:1902109	biolink:NamedThing	negative regulation of mitochondrial membrane permeability involved in apoptotic process	Any negative regulation of mitochondrial membrane permeability that is involved in apoptotic process.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of mitochondrial membrane permeability involved in apoptotic program|negative regulation of mitochondrial membrane permeability involved in programmed cell death by apoptosis|negative regulation of transport across mitochondrial membrane involved in apoptotic program|mitochondrial membrane impermeabilization involved in apoptotic program|negative regulation of transport across mitochondrial membrane involved in apoptotic process|negative regulation of mitochondrial membrane permeability involved in apoptotic programmed cell death|mitochondrial membrane impermeabilization involved in type I programmed cell death|mitochondrial membrane impermeability involved in signaling (initiator) caspase activity|mitochondrial membrane impermeability involved in apoptotic program|mitochondrial membrane impermeability involved in apoptosis|negative regulation of mitochondrial membrane permeability involved in type I programmed cell death|negative regulation of transport across mitochondrial membrane involved in apoptotic cell death|mitochondrial membrane impermeability involved in apoptotic programmed cell death|negative regulation of transport across mitochondrial membrane involved in apoptosis|negative regulation of transport across mitochondrial membrane involved in signaling (initiator) caspase activity|mitochondrial membrane impermeabilization involved in apoptosis|mitochondrial membrane impermeability involved in apoptotic process|negative regulation of mitochondrial membrane permeability involved in apoptosis|mitochondrial membrane impermeabilization involved in apoptotic process|mitochondrial membrane impermeability involved in programmed cell death by apoptosis|mitochondrial membrane impermeabilization involved in apoptotic cell death|mitochondrial membrane impermeabilization involved in signaling (initiator) caspase activity|mitochondrial membrane impermeability involved in type I programmed cell death|mitochondrial membrane impermeabilization involved in programmed cell death by apoptosis|mitochondrial membrane impermeabilization involved in apoptotic programmed cell death|negative regulation of mitochondrial membrane permeability involved in apoptotic cell death|mitochondrial membrane impermeability involved in apoptotic cell death|negative regulation of transport across mitochondrial membrane involved in programmed cell death by apoptosis|negative regulation of mitochondrial membrane permeability involved in signaling (initiator) caspase activity|negative regulation of transport across mitochondrial membrane involved in type I programmed cell death|negative regulation of transport across mitochondrial membrane involved in apoptotic programmed cell death							pr	2013-05-03T12:11:53Z					biological_process											owl:Class	
GO:0051041	biolink:NamedThing	positive regulation of calcium-independent cell-cell adhesion	Any process that activates or increases the frequency, rate or extent of calcium-independent cell-cell adhesion.	tmpzr1t_l9r_go_relaxed.owl	activation of calcium-independent cell-cell adhesion|upregulation of calcium-independent cell-cell adhesion|stimulation of calcium-independent cell-cell adhesion|up-regulation of calcium-independent cell-cell adhesion|up regulation of calcium-independent cell-cell adhesion													biological_process											owl:Class	
GO:0021765	biolink:NamedThing	cingulate gyrus development	The progression of the cingulate gyrus over time from its initial formation until its mature state. The cingulate gyrus is a ridge in the cerebral cortex located dorsal to the corpus callosum.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0033928	biolink:NamedThing	mannan 1,4-mannobiosidase activity	Catalysis of the hydrolysis of (1->4)-beta-D-mannosidic linkages in (1->4)-beta-D-mannans, to remove successive mannobiose residues from the non-reducing chain ends.	tmpzr1t_l9r_go_relaxed.owl	1,4-beta-D-mannan mannobiohydrolase activity|exo-1,4-beta-mannobiohydrolase activity|mannan 1,4-beta-mannobiosidase activity|exo-beta-mannanase activity				EC:3.2.1.100|MetaCyc:3.2.1.100-RXN									molecular_function											owl:Class	
GO:0090488	biolink:NamedThing	polo box domain specific binding	Binding to a polo box domain of a protein. The polo box domain is involved in binding substrates of polo kinases.	tmpzr1t_l9r_go_relaxed.owl								tb	2012-10-16T10:47:30Z					molecular_function											owl:Class	
GO:0062183	biolink:NamedThing	all-trans retinoic acid 18-hydroxylase activity	Catalysis of the reaction: all-trans-retinoate + O2 + reduced [NADPH--hemoprotein reductase] = all-trans-18-hydroxyretinoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase].	tmpzr1t_l9r_go_relaxed.owl					RHEA:55856			dph	2019-11-26T18:41:32Z					molecular_function											owl:Class	
GO:0060451	biolink:NamedThing	negative regulation of hindgut contraction	Any process that decreases the frequency, rate or extent of muscle contraction of the hindgut, the posterior part of the alimentary canal, including the rectum, and the large intestine.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0033204	biolink:NamedThing	ribonuclease P RNA binding	Binding to RNA subunit of ribonuclease P.	tmpzr1t_l9r_go_relaxed.owl	RNase P RNA binding													molecular_function											owl:Class	
GO:0070399	biolink:NamedThing	wall teichoic acid catabolic process	The chemical reactions and pathways resulting in the breakdown of wall teichoic acid, which is a major component of the cell wall of Gram-positive bacteria and typically consists of a polymer of glycerol-phosphate or ribitol-phosphate to which are attached glycosyl and D-alanyl ester residues and which is covalently linked to peptidoglycan.	tmpzr1t_l9r_go_relaxed.owl	wall teichoic acid catabolism|wall teichoic acid breakdown|wall teichoic acid degradation													biological_process											owl:Class	
GO:0070397	biolink:NamedThing	wall teichoic acid metabolic process	The chemical reactions and pathways involving wall teichoic acid, which is a major component of the cell wall of Gram-positive bacteria and typically consists of a polymer of glycerol-phosphate or ribitol-phosphate to which are attached glycosyl and D-alanyl ester residues and which is covalently linked to peptidoglycan.	tmpzr1t_l9r_go_relaxed.owl	WTA metabolic process|wall teichoic acid metabolism													biological_process											owl:Class	
GO:0051119	biolink:NamedThing	sugar transmembrane transporter activity	Enables the transfer of a sugar from one side of a membrane to the other. A sugar is any member of a class of sweet, water-soluble, crystallizable carbohydrates, which are the monosaccharides and smaller oligosaccharides.	tmpzr1t_l9r_go_relaxed.owl	sugar/polyol channel activity				Reactome:R-HSA-8876319|Reactome:R-HSA-8875902|Reactome:R-HSA-428779									molecular_function											owl:Class	
GO:1901272	biolink:NamedThing	2-dehydro-3-deoxy-D-gluconic acid metabolic process	The chemical reactions and pathways involving 2-dehydro-3-deoxy-D-gluconic acid.	tmpzr1t_l9r_go_relaxed.owl	2-dehydro-3-deoxy-D-gluconic acid metabolism							yaf	2012-08-17T14:46:15Z					biological_process											owl:Class	
GO:0008777	biolink:NamedThing	acetylornithine deacetylase activity	Catalysis of the reaction: N2-acetyl-L-ornithine + H2O = acetate + L-ornithine.	tmpzr1t_l9r_go_relaxed.owl	acetylornithinase activity|N2-acetyl-L-ornithine amidohydrolase activity|N-acetylornithinase activity|2-N-acetyl-L-ornithine amidohydrolase activity				EC:3.5.1.16|MetaCyc:ACETYLORNDEACET-RXN|RHEA:15941									molecular_function											owl:Class	
GO:1902498	biolink:NamedThing	regulation of protein autoubiquitination	Any process that modulates the frequency, rate or extent of protein autoubiquitination.	tmpzr1t_l9r_go_relaxed.owl	regulation of protein auto-ubiquitination|regulation of protein auto-ubiquitinylation|regulation of protein self-ubiquitinylation|regulation of protein self-ubiquitination|regulation of protein autoubiquitinylation							rb	2013-11-13T21:03:28Z					biological_process											owl:Class	
GO:0055050	biolink:NamedThing	astral spindle assembly involved in male meiosis	The aggregation, arrangement and bonding together of a set of components to form the astral spindle in male meiotic cells.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0055049	biolink:NamedThing	astral spindle assembly	The aggregation, arrangement and bonding together of a set of components to form the spindle, the array of microtubules and associated molecules that serves to move duplicated chromosomes apart, in the presence of centrosomes.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1901823	biolink:NamedThing	delta-carotene catabolic process	The chemical reactions and pathways resulting in the breakdown of delta-carotene.	tmpzr1t_l9r_go_relaxed.owl	delta-carotene catabolism|delta-carotene degradation|delta-carotene breakdown							yaf	2013-01-22T11:17:34Z					biological_process											owl:Class	
GO:1904973	biolink:NamedThing	positive regulation of viral translation	Any process that activates or increases the frequency, rate or extent of viral translation.	tmpzr1t_l9r_go_relaxed.owl	up regulation of viral protein anabolism|up regulation of viral protein synthesis|activation of viral protein synthesis|up-regulation of viral protein synthesis|upregulation of viral protein anabolism|up-regulation of viral protein biosynthesis|positive regulation of viral protein biosynthesis|activation of viral protein formation|upregulation of viral protein biosynthesis|positive regulation of viral protein formation|positive regulation of viral protein synthesis|positive regulation of viral protein anabolism|activation of viral translation|activation of viral protein biosynthetic process|up regulation of viral protein biosynthesis|up regulation of viral protein formation|upregulation of viral protein synthesis|activation of viral protein biosynthesis|upregulation of viral protein formation|activation of viral protein anabolism|up regulation of viral translation|positive regulation of viral protein biosynthetic process|up regulation of viral protein biosynthetic process|up-regulation of viral protein formation|up-regulation of viral protein anabolism|up-regulation of viral translation|up-regulation of viral protein biosynthetic process|upregulation of viral translation|upregulation of viral protein biosynthetic process							bhm	2016-02-17T15:53:15Z					biological_process											owl:Class	
GO:0030768	biolink:NamedThing	16-methoxy-2,3-dihydro-3-hydroxytabersonine N-methyltransferase activity	Catalysis of the reaction: (3R)-3-hydroxy-16-methoxy-2,3-dihydrotabersonine + S-adenosyl-L-methionine = S-adenosyl-L-homocysteine + deacetoxyvindoline + H(+).	tmpzr1t_l9r_go_relaxed.owl	3-hydroxy-16-methoxy-2,3-dihydrotabersonine N-methyltransferase activity|NMT activity|S-adenosyl-L-methionine:16-methoxy-2,3-dihydro-3-hydroxytabersonine N-methyltransferase activity|16-methoxy-2,3-dihydro-3-hydroxytabersonine methyltransferase activity|S-adenosyl-L-methionine:3-hydroxy-16-methoxy-2,3-dihydrotabersonine N-methyltransferase activity				EC:2.1.1.99|RHEA:11336|KEGG_REACTION:R04013|MetaCyc:2.1.1.99-RXN									molecular_function											owl:Class	
GO:1903553	biolink:NamedThing	positive regulation of extracellular exosome assembly	Any process that activates or increases the frequency, rate or extent of extracellular vesicular exosome assembly.	tmpzr1t_l9r_go_relaxed.owl	up regulation of extracellular vesicular exosome assembly|up-regulation of extracellular vesicular exosome assembly|upregulation of extracellular vesicular exosome assembly|positive regulation of extracellular vesicular exosome assembly|activation of extracellular vesicular exosome assembly							pga	2014-10-20T15:37:42Z					biological_process											owl:Class	
GO:0033386	biolink:NamedThing	geranylgeranyl diphosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of geranylgeranyl diphosphate.	tmpzr1t_l9r_go_relaxed.owl	geranylgeranyl diphosphate biosynthesis|geranylgeranyl diphosphate anabolism|geranylgeranyl diphosphate formation|geranylgeranyl diphosphate synthesis				MetaCyc:PWY-5120|MetaCyc:PWY-5121									biological_process											owl:Class	
GO:0031556	biolink:NamedThing	transcriptional attenuation by ribosome	A type of transcriptional regulation at the level of early termination. This process can occur only in prokaryotes, where transcription of an operon into messenger RNA and translation of that mRNA into polypeptides occur simultaneously. The general principle is that alternative mRNA secondary structures occur under different physiological conditions such as available amount of a particular amino acid. One set of conditions favors early termination of transcription. In the classic example of the trp biosynthesis operon, translation of the gene for a short, trp-containing polypeptide called the trp operon leader peptide pauses either at a trp codon (if tryptophan is scarce) or the stop codon (if trp is readily available). In the former situation transcription continues, but in the latter a Rho-independent terminator forms and reduces, or attenuates, expression of the tryptophan biosynthesis genes. Although the polypeptides encoded by leader peptide genes appear not to be stable once their translation is complete, it is suggested by recent studies that their nascent polypeptide chains interact specifically with ribosomes, specific uncharged tRNAs, or other cellular components to inhibit release at the stop codon and improve the function of transcriptional attenuation as a regulatory switch.	tmpzr1t_l9r_go_relaxed.owl	ribosome-mediated transcriptional attenuation													biological_process											owl:Class	
GO:0120019	biolink:NamedThing	phosphatidylcholine transfer activity	Removes phosphatidylcholine from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle.	tmpzr1t_l9r_go_relaxed.owl	intermembrane phosphatidylcholine transfer activity|phosphatidylcholine carrier activity	https://github.com/geneontology/go-ontology/issues/12329						krc	2017-03-17T04:22:47Z					molecular_function											owl:Class	
GO:0008525	biolink:NamedThing	phosphatidylcholine transporter activity	Enables the directed movement of phosphatidylcholine into, out of or within a cell, or between cells. Phosphatidylcholine refers to a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of choline.	tmpzr1t_l9r_go_relaxed.owl	phosphatidylcholine transmembrane transporter activity													molecular_function											owl:Class	
GO:0050409	biolink:NamedThing	indolylacetylinositol arabinosyltransferase activity	Catalysis of the reaction: 1L-1-O-(indol-3-yl)acetyl-myo-inositol + UDP-L-arabinose = (indol-3-yl)acetyl-myo-inositol 3-L-arabinoside + H(+) + UDP.	tmpzr1t_l9r_go_relaxed.owl	UDP-L-arabinose:indol-3-ylacetyl-myo-inositol L-arabinosyltransferase activity|UDP-L-arabinose:(indol-3-yl)acetyl-myo-inositol L-arabinosyltransferase activity|arabinosylindolylacetylinositol synthase activity				EC:2.4.2.34|RHEA:19505|KEGG_REACTION:R04335|MetaCyc:2.4.2.34-RXN									molecular_function											owl:Class	
GO:0070135	biolink:NamedThing	beta-1,2-oligomannoside metabolic process	The chemical reactions and pathways involving beta-1,2-linked oligomannosides, which are found in fungal cell wall phosphopeptidomannan and phospholipomannan.	tmpzr1t_l9r_go_relaxed.owl	beta-1,2-oligomannoside metabolism													biological_process											owl:Class	
GO:0000430	biolink:NamedThing	regulation of transcription from RNA polymerase II promoter by glucose	Any process involving glucose that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0015431	biolink:NamedThing	ABC-type glutathione S-conjugate transporter activity	Catalysis of the reaction: ATP + H2O + glutathione S-conjugate(in) -> ADP + phosphate + glutathione S-conjugate(out).	tmpzr1t_l9r_go_relaxed.owl	GS-X pump|ATP-dependent glutathione S-conjugate export pump|MRP1/GS-X pump|glutathione S-conjugate-transporting ATPase activity|ATPase-coupled glutathione S-conjugate transmembrane transporter activity|glutathione S-conjugate-exporting ATPase activity|conjugate transporter activity				RHEA:19121|EC:7.6.2.3			mah	2010-10-25T02:32:02Z			GO:0071997		molecular_function											owl:Class	
GO:0007209	biolink:NamedThing	phospholipase C-activating tachykinin receptor signaling pathway	The series of molecular signals generated as a consequence of a tachykinin receptor binding to its physiological ligand, where the pathway proceeds with activation of phospholipase C (PLC) and a subsequent release of inositol trisphosphate (IP3) and diacylglycerol (DAG).	tmpzr1t_l9r_go_relaxed.owl	activation of phospholipase C activity by tachykinin receptor signaling pathway|activation of phospholipase C activity by tachykinin receptor signalling pathway|tachykinin receptor, phospholipase C activating pathway													biological_process											owl:Class	
GO:0090175	biolink:NamedThing	regulation of establishment of planar polarity	Any process that modulates the rate, frequency or extent of the establishment of planar polarity, the coordinated organization of groups of cells in a tissue, such that they all orient to similar coordinates.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-12-14T10:29:41Z					biological_process											owl:Class	
GO:0032137	biolink:NamedThing	guanine/thymine mispair binding	Binding to a double-stranded DNA region containing a G/T mispair.	tmpzr1t_l9r_go_relaxed.owl	G/T mispair binding|T/G mispair binding|thymine/guanine mispair binding													molecular_function											owl:Class	
GO:1901322	biolink:NamedThing	response to chloramphenicol	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chloramphenicol stimulus.	tmpzr1t_l9r_go_relaxed.owl								tb	2012-08-30T00:01:07Z					biological_process											owl:Class	
GO:1900464	biolink:NamedThing	negative regulation of cellular hyperosmotic salinity response by negative regulation of transcription from RNA polymerase II promoter	Any process that stops, prevents, or reduces the frequency, rate or extent of cellular hyperosmotic salinity response by stopping, preventing, or reducing the frequency, rate or extent of transcription from an RNA polymerase II promoter.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of cellular response to hyperosmotic salt stress by negative regulation of transcription from RNA polymerase II promoter							dgf	2012-05-01T07:29:19Z					biological_process											owl:Class	
GO:0070975	biolink:NamedThing	FHA domain binding	Binding to a FHA domain of a protein. The FHA domain is a phosphopeptide recognition domain found in many regulatory proteins, and consists of approximately 80-100 amino acid residues folded into an 11-stranded beta sandwich.	tmpzr1t_l9r_go_relaxed.owl	Forkhead-associated domain binding							mah	2009-10-02T01:09:20Z					molecular_function											owl:Class	
GO:2000921	biolink:NamedThing	regulation of arabinoxylan-containing compound catabolic process	Any process that modulates the frequency, rate or extent of arabinoxylan-containing compound catabolic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of arabinoxylan catabolism							tt	2011-08-01T12:38:56Z					biological_process											owl:Class	
GO:0015872	biolink:NamedThing	dopamine transport	The directed movement of dopamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Dopamine is a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0099643	biolink:NamedThing	signal release from synapse	Any signal release from a synapse.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0019158	biolink:NamedThing	mannokinase activity	Catalysis of the reaction: ATP + D-mannose = ADP + D-mannose 6-phosphate.	tmpzr1t_l9r_go_relaxed.owl	D-fructose (D-mannose) kinase activity|mannokinase (phosphorylating)|ATP:D-mannose 6-phosphotransferase activity				EC:2.7.1.7|RHEA:11028|MetaCyc:MANNKIN-RXN									molecular_function											owl:Class	
GO:0004791	biolink:NamedThing	thioredoxin-disulfide reductase activity	Catalysis of the reaction: NADP(+) + thioredoxin = H(+) + NADPH + thioredoxin disulfide.	tmpzr1t_l9r_go_relaxed.owl	NADP--thioredoxin reductase activity|NADPH--thioredoxin reductase activity|thioredoxin-disulphide reductase activity|thioredoxin reductase (NADPH) activity|thioredoxin disulfide reductase activity|thioredoxin:NADP+ oxidoreductase activity|NADPH:oxidized thioredoxin oxidoreductase activity|NADPH2:oxidized thioredoxin oxidoreductase activity				MetaCyc:THIOREDOXIN-REDUCT-NADPH-RXN|Reactome:R-HSA-9617735|Reactome:R-HSA-3323050|EC:1.8.1.9|Reactome:R-HSA-1222485|RHEA:20345|Reactome:R-HSA-73646|KEGG_REACTION:R02016									molecular_function											owl:Class	
GO:0034108	biolink:NamedThing	positive regulation of erythrocyte clearance	Any process that activates or increases the frequency, rate, or extent of erythrocyte clearance.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of red blood cell clearance|positive regulation of RBC clearance|positive regulation of neocytolysis													biological_process											owl:Class	
GO:0042136	biolink:NamedThing	neurotransmitter biosynthetic process	The chemical reactions and pathways resulting in the formation of any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell.	tmpzr1t_l9r_go_relaxed.owl	neurotransmitter formation|neurotransmitter anabolism|neurotransmitter biosynthesis and storage|neurotransmitter biosynthetic process and storage|neurotransmitter biosynthesis|neurotransmitter synthesis													biological_process											owl:Class	
GO:0099102	biolink:NamedThing	G-protein gated potassium channel activity involved in regulation of postsynaptic membrane potential	Any G-protein gated potassium channel activity that is involved regulation of postsynaptic membrane potential.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0045015	biolink:NamedThing	HDEL sequence binding	Binding to a HDEL sequence, the C terminus tetrapeptide sequence His-Asp-Glu-Leu found in proteins that are to be retained in the endoplasmic reticulum.	tmpzr1t_l9r_go_relaxed.owl	HDEL receptor activity													molecular_function											owl:Class	
GO:0045992	biolink:NamedThing	negative regulation of embryonic development	Any process that stops, prevents, or reduces the frequency, rate or extent of embryonic development.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of embryonic development|downregulation of embryonic development|inhibition of embryonic development|down regulation of embryonic development													biological_process											owl:Class	
GO:0016488	biolink:NamedThing	farnesol catabolic process	The chemical reactions and pathways resulting in the breakdown of the sesquiterpenoid alcohol farnesol, 3,7,11-trimethyl-2,6,10,dodecatrien-1-ol.	tmpzr1t_l9r_go_relaxed.owl	farnesol catabolism|farnesol breakdown|farnesol degradation													biological_process											owl:Class	
GO:0016487	biolink:NamedThing	farnesol metabolic process	The chemical reactions and pathways involving the sesquiterpenoid alcohol farnesol, 3,7,11-trimethyl-2,6,10,dodecatrien-1-ol.	tmpzr1t_l9r_go_relaxed.owl	farnesol metabolism													biological_process											owl:Class	
GO:0021658	biolink:NamedThing	rhombomere 3 morphogenesis	The process in which the anatomical structure of rhombomere 3 is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1903845	biolink:NamedThing	negative regulation of cellular response to transforming growth factor beta stimulus	Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to transforming growth factor beta stimulus.	tmpzr1t_l9r_go_relaxed.owl	inhibition of cellular response to TGFbeta stimulus|downregulation of cellular response to transforming growth factor beta stimulus|down-regulation of cellular response to TGFbeta stimulus|inhibition of cellular response to TGF-beta stimulus|negative regulation of cellular response to TGFbeta stimulus|downregulation of cellular response to TGFbeta stimulus|down-regulation of cellular response to TGF-beta stimulus|negative regulation of cellular response to TGF-beta stimulus|down regulation of cellular response to TGF-beta stimulus|down-regulation of cellular response to transforming growth factor beta stimulus|down regulation of cellular response to transforming growth factor beta stimulus|inhibition of cellular response to transforming growth factor beta stimulus|downregulation of cellular response to TGF-beta stimulus|down regulation of cellular response to TGFbeta stimulus							rph	2015-01-23T11:25:21Z					biological_process											owl:Class	
GO:0047105	biolink:NamedThing	4-trimethylammoniobutyraldehyde dehydrogenase activity	Catalysis of the reaction: NAD+ + 4-trimethylammoniobutanal = NADH + 4-trimethylammoniobutanoate.	tmpzr1t_l9r_go_relaxed.owl	4-trimethylammoniobutanal:NAD+ 1-oxidoreductase activity|4-N-trimethylaminobutyraldehyde dehydrogenase activity|4-trimethylaminobutyraldehyde dehydrogenase activity				MetaCyc:1.2.1.47-RXN|EC:1.2.1.47|RHEA:17985									molecular_function											owl:Class	
GO:0061570	biolink:NamedThing	dCDP phosphorylation	The process of introducing a phosphate group into dCDP to produce a dCTP.	tmpzr1t_l9r_go_relaxed.owl								dph	2013-08-01T13:02:16Z					biological_process											owl:Class	
GO:1902273	biolink:NamedThing	negative regulation of (R)-carnitine transmembrane transport	Any process that stops, prevents or reduces the frequency, rate or extent of (R)-carnitine transmembrane transport.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of (R)-carnitine transmembrane transport|down regulation of (R)-carnitine transmembrane transport|downregulation of (R)-carnitine transmembrane transport|inhibition of (R)-carnitine transmembrane transport							mcc	2013-07-01T13:13:17Z					biological_process											owl:Class	
GO:0036397	biolink:NamedThing	formate dehydrogenase (quinone) activity	Catalysis of the reaction: formate + a quinone = CO2 + a quinol.	tmpzr1t_l9r_go_relaxed.owl	formate:quinone oxidoreductase activity|formate dehydrogenase-N activity|Fdh-N activity	https://github.com/geneontology/go-ontology/issues/21412			EC:1.17.5.3|MetaCyc:FORMATEDEHYDROG-RXN|RHEA:48592|KEGG_REACTION:R09494	Formerly EC:1.1.5.6.		bf	2013-07-18T13:11:41Z					molecular_function											owl:Class	
GO:0061369	biolink:NamedThing	negative regulation of testicular blood vessel morphogenesis	Any process that stops, prevents, or reduces the frequency, rate or extent of blood vessel morphogenesis in the testicle.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of testicular vasculature morphogenesis							dph	2010-10-27T02:47:14Z					biological_process											owl:Class	
GO:0043795	biolink:NamedThing	glyceraldehyde oxidoreductase activity	Catalysis of the reaction: A + D-glyceraldehyde + H2O = (R)-glycerate + AH2 + H(+).	tmpzr1t_l9r_go_relaxed.owl					RHEA:36047|EC:1.2.99.8									molecular_function											owl:Class	
GO:0008726	biolink:NamedThing	alkanesulfonate monooxygenase activity	Catalysis of the reaction: an alkanesulfonate + O2 + FMNH2 = an aldehyde + sulfite + H2O + FMN.	tmpzr1t_l9r_go_relaxed.owl	SsuD|alkanesulphonate monooxygenase activity|alkanesulfonate, reduced-FMN:oxygen oxidoreductase activity|FMNH2-dependent aliphatic sulfonate monooxygenase activity|FMNH(2)-dependent aliphatic sulfonate monooxygenase activity|sulfate starvation-induced protein 6 activity|FMNH(2)-dependent alkanesulfonate monooxygenase activity				MetaCyc:RXN0-280|EC:1.14.14.5|RHEA:23064									molecular_function											owl:Class	
GO:0032738	biolink:NamedThing	positive regulation of interleukin-15 production	Any process that activates or increases the frequency, rate, or extent of interleukin-15 production.	tmpzr1t_l9r_go_relaxed.owl	stimulation of interleukin-15 production|up-regulation of interleukin-15 production|positive regulation of interleukin-15 biosynthetic process|positive regulation of IL-15 production|activation of interleukin-15 production|up regulation of interleukin-15 production|upregulation of interleukin-15 production											GO:0045374		biological_process											owl:Class	
GO:0021799	biolink:NamedThing	cerebral cortex radially oriented cell migration	The migration of cells in the developing cerebral cortex in which cells move from the ventricular and/or subventricular zone toward the surface of the brain.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0021795	biolink:NamedThing	cerebral cortex cell migration	The orderly movement of cells from one site to another in the cerebral cortex.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0070597	biolink:NamedThing	cell wall (1->3)-alpha-glucan metabolic process	The chemical reactions and pathways involving (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds, found in the walls of cells.	tmpzr1t_l9r_go_relaxed.owl	cell wall 1,3-alpha-glucan metabolism|cell wall alpha-1,3 glucan metabolic process|cell wall alpha-1,3 glucan metabolism|cell wall 1,3-alpha-glucan metabolic process							mah	2009-04-28T04:03:00Z					biological_process											owl:Class	
GO:1904334	biolink:NamedThing	heme import across plasma membrane	The directed movement of heme from outside of a cell, across the plasma membrane and into the cytosol.	tmpzr1t_l9r_go_relaxed.owl	heme assimilation							al	2015-06-11T16:56:21Z					biological_process											owl:Class	
GO:0045016	biolink:NamedThing	mitochondrial magnesium ion transmembrane transport	The process in which a magnesium ion (Mg2+) is transported across a mitochondrial membrane, into or out of the mitochondrion.	tmpzr1t_l9r_go_relaxed.owl	mitochondrial magnesium ion transport							mcc	2015-01-21T17:44:38Z			GO:1990614		biological_process											owl:Class	
GO:0019289	biolink:NamedThing	rhizobactin 1021 biosynthetic process	The chemical reactions and pathways resulting in the formation of rhizobactin 1021, (E)-4-((3-(acetylhydroxyamino)propyl)-amino)-2-hydroxy-(2-(2-(3-(hydroxy(1-oxo-2-decenyl)amino)propyl)amino)-2-oxoethyl)-4-oxobutanoic acid, a siderophore produced by Sinorhizobium meliloti.	tmpzr1t_l9r_go_relaxed.owl	rhizobactin 1021 biosynthetic process, peptide modification|rhizobactin 1021 formation|rhizobactin 1021 biosynthesis|rhizobactin 1021 biosynthetic process, peptide formation|rhizobactin 1021 synthesis|rhizobactin 1021 anabolism				MetaCyc:PWY-761							GO:0031194|GO:0031193		biological_process											owl:Class	
GO:0140616	biolink:NamedThing	iodotyrosine deiodinase activity	Catalyzes the reaction: 2 iodide + L-tyrosine + 2 NADP+ = 3,5-diiodo-L-tyrosine + H+ + 2 NADPH.	tmpzr1t_l9r_go_relaxed.owl	monoiodotyrosine deiodinase activity|tyrosine iodinase activity|iodide peroxidase-tyrosine iodinase activity|iodotyrosine deiodase activity	https://github.com/geneontology/go-ontology/issues/21027			EC:1.21.1.1|RHEA:32479			pg	2021-03-08T15:36:42Z					molecular_function											owl:Class	
GO:0006072	biolink:NamedThing	glycerol-3-phosphate metabolic process	The chemical reactions and pathways involving glycerol-3-phosphate, a phosphoric monoester of glycerol.	tmpzr1t_l9r_go_relaxed.owl	glycerol-3-phosphate metabolism													biological_process											owl:Class	
GO:0015130	biolink:NamedThing	mevalonate transmembrane transporter activity	Enables the transfer of mevalonate from one side of a membrane to the other. Mevalonate is the anion of mevalonic acid; its (R)-enantiomer is a strategic intermediate derived from hydroxymethylglutaryl-CoA in the biosynthesis of polyprenyl compounds.	tmpzr1t_l9r_go_relaxed.owl	monocarboxylate (lactate, pyruvate, mevalonate) uptake/efflux porter activity													molecular_function											owl:Class	
GO:0005963	biolink:NamedThing	magnesium-dependent protein serine/threonine phosphatase complex	An enzyme complex that catalyzes the removal of serine- or threonine-bound phosphate groups from a wide range of phosphoproteins, including a number of enzymes that have been phosphorylated under the action of a kinase.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0001872	biolink:NamedThing	(1->3)-beta-D-glucan binding	Binding to a (1->3)-beta-D-glucan.	tmpzr1t_l9r_go_relaxed.owl	1,3-beta-D-glucan binding|zymosan binding|callose binding											GO:0080087		molecular_function											owl:Class	
GO:0018885	biolink:NamedThing	carbon tetrachloride metabolic process	The chemical reactions and pathways involving carbon tetrachloride, a toxic, carcinogenic compound which is used as a general solvent in industrial degreasing operations. It is also used as grain fumigant and a chemical intermediate in the production of refrigerants.	tmpzr1t_l9r_go_relaxed.owl	carbon tetrachloride metabolism				UM-BBD_pathwayID:ctc									biological_process											owl:Class	
GO:0045643	biolink:NamedThing	regulation of eosinophil differentiation	Any process that modulates the frequency, rate or extent of eosinophil differentiation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0097619	biolink:NamedThing	PTEX complex	A protein complex that acts as a protein trafficking machinery and is responsible for the export of proteins across the parasitophorous (symbiont-containing) vacuolar membrane and into the human host cell. The PTEX complex is located in the vacuole membrane. It is ATP-powered, and comprises heat shock protein 101 (HSP101; a ClpA/B-like ATPase from the AAA+ superfamily, of a type commonly associated with protein translocons), a parasite protein termed PTEX150, and exported protein 2 (EXP2). EXP2 is the potential channel, as it is the membrane-associated component of the core PTEX complex. Two other proteins, PTEX88 and thioredoxin 2 (TRX2), were also identified as PTEX components.	tmpzr1t_l9r_go_relaxed.owl	Plasmodium translocon of exported proteins							pr	2014-07-29T16:05:32Z					cellular_component											owl:Class	
GO:0032256	biolink:NamedThing	establishment of dense core granule localization	The directed movement of a dense core granule to a specific location.	tmpzr1t_l9r_go_relaxed.owl	establishment of dense core granule localisation|establishment of dense core vesicle localization													biological_process											owl:Class	
GO:1902998	biolink:NamedThing	positive regulation of neurofibrillary tangle assembly	Any process that activates or increases the frequency, rate or extent of neurofibrillary tangle assembly.	tmpzr1t_l9r_go_relaxed.owl	activation of star-shaped neurofibrillary tangle formation|activation of flame-shaped neurofibrillary tangle formation|positive regulation of neurofibrillary tangle formation|up-regulation of flame-shaped neurofibrillary tangle formation|upregulation of star-shaped neurofibrillary tangle assembly|up regulation of flame-shaped neurofibrillary tangle formation|up-regulation of neurofibrillary tangle formation|activation of star-shaped neurofibrillary tangle assembly|activation of flame-shaped neurofibrillary tangle assembly|up regulation of star-shaped neurofibrillary tangle assembly|positive regulation of star-shaped neurofibrillary tangle formation|positive regulation of flame-shaped neurofibrillary tangle formation|positive regulation of star-shaped neurofibrillary tangle assembly|up-regulation of flame-shaped neurofibrillary tangle assembly|activation of neurofibrillary tangle assembly|upregulation of star-shaped neurofibrillary tangle formation|upregulation of flame-shaped neurofibrillary tangle assembly|up-regulation of star-shaped neurofibrillary tangle formation|up regulation of star-shaped neurofibrillary tangle formation|up regulation of neurofibrillary tangle formation|up regulation of flame-shaped neurofibrillary tangle assembly|up regulation of neurofibrillary tangle assembly|upregulation of flame-shaped neurofibrillary tangle formation|positive regulation of flame-shaped neurofibrillary tangle assembly|upregulation of neurofibrillary tangle formation|upregulation of neurofibrillary tangle assembly|up-regulation of neurofibrillary tangle assembly|activation of neurofibrillary tangle formation|up-regulation of star-shaped neurofibrillary tangle assembly							sjp	2014-05-08T15:44:45Z					biological_process											owl:Class	
GO:1902996	biolink:NamedThing	regulation of neurofibrillary tangle assembly	Any process that modulates the frequency, rate or extent of neurofibrillary tangle assembly.	tmpzr1t_l9r_go_relaxed.owl	regulation of neurofibrillary tangle formation|regulation of flame-shaped neurofibrillary tangle assembly|regulation of flame-shaped neurofibrillary tangle formation|regulation of star-shaped neurofibrillary tangle assembly|regulation of star-shaped neurofibrillary tangle formation							sjp	2014-05-08T15:44:27Z					biological_process											owl:Class	
GO:0039511	biolink:NamedThing	suppression by virus of host interferon receptor activity	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of the functional activity of a host interferon receptor.	tmpzr1t_l9r_go_relaxed.owl	down-regulation by virus of host interferon receptor activity|negative regulation by virus of host interferon receptor activity|inhibition by virus of host interferon receptor activity|inhibition of host interferon receptors by virus|downregulation by virus of host interferon receptor activity				VZ:843			bf	2011-06-16T02:24:05Z					biological_process											owl:Class	
GO:0051476	biolink:NamedThing	mannosylglycerate transport	The directed movement of mannosylglycerate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1900496	biolink:NamedThing	positive regulation of butyryl-CoA biosynthetic process from acetyl-CoA	Any process that activates or increases the frequency, rate or extent of butyryl-CoA biosynthetic process from acetyl-CoA.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of butyryl-CoA biosynthetic process from acetyl-CoA|upregulation of butyryl-CoA biosynthetic process from acetyl-CoA|up-regulation of butyryl-CoA biosynthesis from acetyl-CoA|activation of butyryl-CoA biosynthetic process from acetyl-CoA|positive regulation of butyryl-CoA biosynthesis from acetyl-CoA|upregulation of butyryl-CoA biosynthesis from acetyl-CoA|activation of butyryl-CoA biosynthesis from acetyl-CoA|up regulation of butyryl-CoA biosynthetic process from acetyl-CoA|up regulation of butyryl-CoA biosynthesis from acetyl-CoA							tt	2012-05-02T03:51:58Z					biological_process											owl:Class	
GO:0033468	biolink:NamedThing	CMP-keto-3-deoxy-D-manno-octulosonic acid biosynthetic process	The chemical reactions and pathways resulting in the formation of CMP-keto-3-deoxy-D-manno-octulosonic acid, a substance composed of the acidic sugar 3-deoxy-D-manno-octulosonic acid in glycosidic linkage with cytidine monophosphate.	tmpzr1t_l9r_go_relaxed.owl	CMP-keto-3-deoxy-D-manno-octulosonic acid anabolism|CMP-keto-3-deoxy-D-manno-octulosonic acid synthesis|CMP-KDO biosynthetic process|CMP-KDO biosynthesis|CMP-keto-3-deoxy-D-manno-octulosonic acid biosynthesis|CMP-ketodeoxyoctanoate biosynthetic process|CMP-keto-3-deoxy-D-manno-octulosonic acid formation				MetaCyc:PWY-5111|MetaCyc:KDOSYN-PWY|MetaCyc:PWY-1269									biological_process											owl:Class	
GO:0051409	biolink:NamedThing	response to nitrosative stress	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrosative stress stimulus. Nitrosative stress is a state often resulting from exposure to high levels of nitric oxide (NO) or the highly reactive oxidant peroxynitrite, which is produced following interaction of NO with superoxide anions.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0036103	biolink:NamedThing	Kdo2-lipid A metabolic process	The chemical reactions and pathways involving Kdo2-lipid A, a lipopolysaccharide (LPS) component.	tmpzr1t_l9r_go_relaxed.owl	Kdo2-lipid A metabolism							bf	2012-01-27T01:49:16Z					biological_process											owl:Class	
GO:1901437	biolink:NamedThing	regulation of toluene metabolic process	Any process that modulates the frequency, rate or extent of toluene metabolic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of methylbenzene metabolism|regulation of toluene metabolism|regulation of methylbenzene metabolic process							tt	2012-10-01T21:17:41Z					biological_process											owl:Class	
GO:0003990	biolink:NamedThing	acetylcholinesterase activity	Catalysis of the reaction: acetylcholine + H2O = choline + acetate.	tmpzr1t_l9r_go_relaxed.owl	acetylthiocholinesterase activity|acetylcholine hydrolase activity|choline esterase I activity|AcCholE|true cholinesterase activity|acetyl.beta-methylcholinesterase activity|acetylcholine acetylhydrolase activity				EC:3.1.1.7|MetaCyc:ACETYLCHOLINESTERASE-RXN|Reactome:R-HSA-372519|RHEA:17561									molecular_function											owl:Class	
GO:0004104	biolink:NamedThing	cholinesterase activity	Catalysis of the reaction: an acylcholine + H2O = choline + a carboxylic acid anion.	tmpzr1t_l9r_go_relaxed.owl	acylcholine acylhydrolase activity|butyrylcholinesterase activity|non-specific cholinesterase activity|choline esterase II (unspecific) activity|benzoylcholinesterase activity|BtChoEase activity|propionylcholinesterase activity|anticholineesterase activity|pseudocholinesterase activity|butyrylcholine esterase activity|choline esterase activity				EC:3.1.1.8|RHEA:21964|MetaCyc:CHOLINESTERASE-RXN									molecular_function											owl:Class	
GO:0035641	biolink:NamedThing	locomotory exploration behavior	The specific movement from place to place of an organism in response to a novel environment.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-01-19T10:40:04Z					biological_process											owl:Class	
GO:0035640	biolink:NamedThing	exploration behavior	The specific behavior of an organism in response to a novel environment or stimulus.	tmpzr1t_l9r_go_relaxed.owl	open-field behavior|exploratory behavior|exploration behaviour|exploratory behaviour					For changes in locomotory behavior upon introduction to a novel environment, consider instead the child term: locomotory exploration behavior ; GO:0035641.		bf	2011-01-19T10:35:45Z					biological_process											owl:Class	
GO:0034345	biolink:NamedThing	negative regulation of type III interferon production	Any process that stops, prevents, or reduces the frequency, rate, or extent of type III interferon production. Interferon lambda is the only member of the type III interferon found so far.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of type III IFN production|inhibition of type III interferon production|down-regulation of type III interferon production|down regulation of type III interferon production|downregulation of type III interferon production					Note that IL-28A, IL-28B, and IL-29 are types of interferon-lambda.								biological_process											owl:Class	
GO:0015730	biolink:NamedThing	propanoate transport	The directed movement of propionate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	propionate transport													biological_process											owl:Class	
GO:0015912	biolink:NamedThing	short-chain fatty acid transport	The directed movement of short-chain fatty acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Short-chain fatty acids are fatty acids with a chain length of less than C6.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0001073	biolink:NamedThing	transcription antitermination factor activity, DNA binding	Binds to DNA, typically within region of the promoter and transcribed region, to promote readthrough of a transcription termination site and thus extending the length of the RNA transcript produced. Examples of antitermination factors which bind DNA include the lambda Q protein.	tmpzr1t_l9r_go_relaxed.owl	DNA binding transcription antitermination factor activity							krc	2010-10-21T05:18:52Z					molecular_function											owl:Class	
GO:0046319	biolink:NamedThing	positive regulation of glucosylceramide biosynthetic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glucosylceramide.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of glucosylceramide synthesis|stimulation of glucosylceramide biosynthetic process|positive regulation of glucosylceramide anabolism|activation of glucosylceramide biosynthetic process|positive regulation of glucosylceramide biosynthesis|up regulation of glucosylceramide biosynthetic process|up-regulation of glucosylceramide biosynthetic process|upregulation of glucosylceramide biosynthetic process|positive regulation of glucosylceramide formation													biological_process											owl:Class	
GO:1904439	biolink:NamedThing	negative regulation of iron ion import across plasma membrane	Any process that stops, prevents or reduces the frequency, rate or extent of iron ions import across plasma membrane.	tmpzr1t_l9r_go_relaxed.owl	inhibition of ferrous iron import across plasma membrane|down regulation of ferrous iron import across plasma membrane|inhibition of ferrous ion import into cell|downregulation of ferrous ion import into cell|down-regulation of ferrous iron import across plasma membrane|down-regulation of ferrous ion import into cell|downregulation of ferrous iron import across plasma membrane|negative regulation of ferrous iron import across plasma membrane|negative regulation of ferrous ion import into cell|down regulation of ferrous ion import into cell|negative regulation of ferrous iron import into cell							rl	2015-07-06T13:49:58Z			GO:1903990		biological_process											owl:Class	
GO:0045798	biolink:NamedThing	negative regulation of chromatin assembly or disassembly	Any process that stops, prevents, or reduces the frequency, rate or extent of chromatin assembly or disassembly.	tmpzr1t_l9r_go_relaxed.owl	downregulation of chromatin assembly or disassembly|negative regulation of chromatin assembly/disassembly|down-regulation of chromatin assembly or disassembly|inhibition of chromatin assembly or disassembly|down regulation of chromatin assembly or disassembly													biological_process											owl:Class	
GO:1905662	biolink:NamedThing	negative regulation of telomerase RNA reverse transcriptase activity	Any process that stops, prevents or reduces the frequency, rate or extent of telomerase RNA reverse transcriptase activity.	tmpzr1t_l9r_go_relaxed.owl	downregulation of telomerase, catalyst|inhibition of telomerase, catalyst|negative regulation of telomerase, catalyst|down-regulation of telomerase, catalyst|inhibition of telomerase RNA reverse transcriptase activity|down-regulation of telomerase RNA reverse transcriptase activity|down regulation of telomerase RNA reverse transcriptase activity|downregulation of telomerase RNA reverse transcriptase activity|down regulation of telomerase, catalyst							nc	2016-11-09T16:55:28Z					biological_process											owl:Class	
GO:0003424	biolink:NamedThing	establishment of cell polarity involved in growth plate cartilage chondrocyte division	The cellular process that results in the specification, formation or maintenance of anisotropic intracellular organization that results in the directional division of a growth plate cartilage chondrocyte.	tmpzr1t_l9r_go_relaxed.owl	growth plate cartilage chondrocyte polarization							dph	2009-12-22T10:18:10Z					biological_process											owl:Class	
GO:0008594	biolink:NamedThing	photoreceptor cell morphogenesis	The process in which the structures of a photoreceptor cell are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a photoreceptor cell, a sensory cell that reacts to the presence of light. An example of this is found in Drosophila melanogaster.	tmpzr1t_l9r_go_relaxed.owl	photoreceptor development													biological_process											owl:Class	
GO:0090201	biolink:NamedThing	negative regulation of release of cytochrome c from mitochondria	Any process that decreases the rate, frequency or extent of release of cytochrome c from mitochondria, the process in which cytochrome c is enabled to move from the mitochondrial intermembrane space into the cytosol, which is an early step in apoptosis and leads to caspase activation.	tmpzr1t_l9r_go_relaxed.owl						The release of cytochrome c from mitochondria is a central event in the signaling phase of the apoptotic process, and it is often used by researchers to monitor this type of cell death. Any event that induces apoptosis will at some point induce the release of cytochrome c from mitochondria. Therefore, this term should only be used to annotate gene products that directly and negatively regulate this process.		tb	2009-12-18T11:35:20Z					biological_process											owl:Class	
GO:0090199	biolink:NamedThing	regulation of release of cytochrome c from mitochondria	Any process that modulates the rate, frequency or extent of release of cytochrome c from mitochondria, the process in which cytochrome c is enabled to move from the mitochondrial intermembrane space into the cytosol, which is an early step in apoptosis and leads to caspase activation.	tmpzr1t_l9r_go_relaxed.owl						The release of cytochrome c from mitochondria is a central event in the signaling phase of the apoptotic process, and it is often used by researchers to monitor this type of cell death. Any event that induces apoptosis will at some point induce the release of cytochrome c from mitochondria. Therefore, this term should only be used to annotate gene products that directly regulate this process.		tb	2009-12-18T11:35:20Z					biological_process											owl:Class	
GO:0009255	biolink:NamedThing	Entner-Doudoroff pathway through 6-phosphogluconate	A pathway that converts a carbohydrate to pyruvate and glyceraldehyde-3 phosphate by producing 6-phosphogluconate and then dehydrating it.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:ENTNER-DOUDOROFF-PWY-I									biological_process											owl:Class	
GO:0090327	biolink:NamedThing	negative regulation of locomotion involved in locomotory behavior	Any process that decreases the frequency, rate, or extent of the self-propelled movement of a cell or organism from one location to another in a behavioral context; the aspect of locomotory behavior having to do with movement.	tmpzr1t_l9r_go_relaxed.owl								tb	2010-05-14T10:26:58Z					biological_process											owl:Class	
GO:0051724	biolink:NamedThing	NAD transmembrane transporter activity	Enables the transfer of NAD from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	NAD transporter activity|NAD (oxidized) transporter activity|nicotinamide adenine dinucleotide transmembrane transporter activity|NAD (reduced) transporter activity|oxidized NAD transporter activity|reduced nicotinamide adenine dinucleotide transmembrane transporter activity|NAD+ transporter activity|reduced NAD transporter activity|oxidized nicotinamide adenine dinucleotide transmembrane transporter activity|NADH transporter activity					NAD carrier		jl	2012-09-19T13:21:08Z			GO:1901368		molecular_function											owl:Class	
GO:1905592	biolink:NamedThing	negative regulation of optical nerve axon regeneration	Any process that stops, prevents or reduces the frequency, rate or extent of optical nerve axon regeneration.	tmpzr1t_l9r_go_relaxed.owl	inhibition of optical nerve axon regeneration|down-regulation of optical nerve axon regeneration|down regulation of optical nerve axon regeneration|downregulation of optical nerve axon regeneration							pga	2016-10-25T12:58:50Z					biological_process											owl:Class	
GO:1902812	biolink:NamedThing	regulation of BMP signaling pathway involved in determination of lateral mesoderm left/right asymmetry	Any process that modulates the frequency, rate or extent of BMP signaling pathway involved in determination of lateral mesoderm left/right asymmetry.	tmpzr1t_l9r_go_relaxed.owl	regulation of BMP signalling pathway involved in determination of lateral mesoderm left/right asymmetry|regulation of BMP signaling pathway involved in lateral mesoderm left/right asymmetry determination							mr	2014-03-26T21:18:44Z					biological_process											owl:Class	
GO:0071908	biolink:NamedThing	determination of intestine left/right asymmetry	Determination of the asymmetric location of the intestine loops with respect to the left and right halves of the organism.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-09-22T10:24:33Z					biological_process											owl:Class	
GO:0071907	biolink:NamedThing	determination of digestive tract left/right asymmetry	Determination of the asymmetric location of various parts of the digestive tract with respect to the left and right halves of the organism. The digestive tract is the anatomical structure through which food passes and is processed.	tmpzr1t_l9r_go_relaxed.owl	determination of gut left/right asymmetry|determination of left/right asymmetry of the digestive tract							mah	2010-09-22T10:14:29Z					biological_process											owl:Class	
GO:0034716	biolink:NamedThing	Gemin3-Gemin4-Gemin5 complex	A protein complex that contains Gemin3 (DDX20), Gemin4, and Gemin5, and can bind to snRNAs; may be an intermediate in SMN complex assembly.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0035561	biolink:NamedThing	regulation of chromatin binding	Any process that modulates the frequency, rate or extent of chromatin binding. Chromatin binding is the selective interaction with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.	tmpzr1t_l9r_go_relaxed.owl								bf	2010-05-19T10:28:36Z					biological_process											owl:Class	
GO:0061518	biolink:NamedThing	microglial cell proliferation	The expansion of a microglial cell population by cell division.	tmpzr1t_l9r_go_relaxed.owl								dph	2013-04-18T13:20:21Z					biological_process											owl:Class	
GO:0061517	biolink:NamedThing	macrophage proliferation	The expansion of a macrophage population by cell division.	tmpzr1t_l9r_go_relaxed.owl								dph	2013-04-18T13:17:56Z					biological_process											owl:Class	
GO:0005163	biolink:NamedThing	nerve growth factor receptor binding	Binding to a nerve growth factor receptor.	tmpzr1t_l9r_go_relaxed.owl	neurotrophin|NGF receptor binding|nerve growth factor receptor ligand													molecular_function											owl:Class	
GO:1900973	biolink:NamedThing	positive regulation of sarcinapterin biosynthetic process	Any process that activates or increases the frequency, rate or extent of sarcinapterin biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	upregulation of sarcinapterin anabolism|upregulation of sarcinapterin synthesis|up-regulation of sarcinapterin formation|up regulation of sarcinapterin anabolism|up regulation of sarcinapterin biosynthesis|up-regulation of sarcinapterin biosynthetic process|activation of sarcinapterin synthesis|up-regulation of sarcinapterin biosynthesis|upregulation of sarcinapterin formation|up-regulation of sarcinapterin anabolism|upregulation of sarcinapterin biosynthetic process|positive regulation of sarcinapterin synthesis|activation of sarcinapterin biosynthesis|activation of sarcinapterin anabolism|up-regulation of sarcinapterin synthesis|up regulation of sarcinapterin biosynthetic process|activation of sarcinapterin formation|activation of sarcinapterin biosynthetic process|up regulation of sarcinapterin synthesis|up regulation of sarcinapterin formation|positive regulation of sarcinapterin anabolism|upregulation of sarcinapterin biosynthesis|positive regulation of sarcinapterin biosynthesis|positive regulation of sarcinapterin formation							tt	2012-06-14T04:00:14Z					biological_process											owl:Class	
GO:0050293	biolink:NamedThing	steroid-lactonase activity	Catalysis of the reaction: H(2)O + testololactone = H(+) + testolate.	tmpzr1t_l9r_go_relaxed.owl	testololactone lactonohydrolase activity				EC:3.1.1.37|RHEA:13721|KEGG_REACTION:R03641|MetaCyc:STEROID-LACTONASE-RXN									molecular_function											owl:Class	
GO:1900813	biolink:NamedThing	monodictyphenone metabolic process	The chemical reactions and pathways involving monodictyphenone.	tmpzr1t_l9r_go_relaxed.owl	monodictyphenone metabolism							di	2012-06-04T10:11:03Z					biological_process											owl:Class	
GO:0047414	biolink:NamedThing	2-(hydroxymethyl)-3-(acetamidomethylene)succinate hydrolase activity	Catalysis of the reaction: (2Z)-2-(acetamidomethylene)-3-(hydroxymethyl)succinate + 2 H(2)O + H(+) = 2-(hydroxymethyl)-4-oxobutanoate + acetate + CO(2) + NH(4)(+).	tmpzr1t_l9r_go_relaxed.owl	2-(hydroxymethyl)-3-(acetamidomethylene)succinate amidohydrolase (deaminating, decarboxylating)|alpha-hydroxymethyl-alpha'-(N-acetylaminomethylene)succinic acid hydrolase activity|compound B hydrolase activity				Wikipedia:2-(hydroxymethyl)-3-(acetamidomethylene)succinate_amidohydrolase_(deaminating,_decarboxylating)|MetaCyc:3.5.1.66-RXN|RHEA:17677|KEGG_REACTION:R04397|EC:3.5.1.66									molecular_function											owl:Class	
GO:1901153	biolink:NamedThing	paromomycin metabolic process	The chemical reactions and pathways involving paromomycin.	tmpzr1t_l9r_go_relaxed.owl	paromomycin metabolism							yaf	2012-07-17T04:27:20Z					biological_process											owl:Class	
GO:0008910	biolink:NamedThing	kanamycin kinase activity	Catalysis of the reaction: ATP + kanamycin = ADP + 2 H(+) + kanamycin 3'-phosphate.	tmpzr1t_l9r_go_relaxed.owl	ATP:kanamycin 3'-O-phosphotransferase activity|neomycin-kanamycin phosphotransferase activity|APH(3') activity|neomycin phosphotransferase activity|aminoglycoside 3'-phosphotransferase activity|kanamycin kinase (phosphorylating)				EC:2.7.1.95|KEGG_REACTION:R01888|MetaCyc:KANAMYCIN-KINASE-RXN|RHEA:24256									molecular_function											owl:Class	
GO:0070252	biolink:NamedThing	actin-mediated cell contraction	The actin filament-based process in which cytoplasmic actin filaments slide past one another resulting in contraction of all or part of the cell body.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0038124	biolink:NamedThing	toll-like receptor TLR6:TLR2 signaling pathway	A series of molecular signals initiated by the binding of a heterodimeric TLR6:TLR2 complex to one of it's physiological ligands, followed by transmission of the signal by the activated receptor, and ending with regulation of a downstream cellular process, e.g. transcription.	tmpzr1t_l9r_go_relaxed.owl	TLR2:TLR6 signaling pathway|toll-like receptor TLR6:TLR2 signalling pathway							bf	2012-03-23T10:29:09Z					biological_process											owl:Class	
GO:0050352	biolink:NamedThing	trimethylamine-oxide aldolase activity	Catalysis of the reaction: H(+) + trimethylamine N-oxide = dimethylamine + formaldehyde.	tmpzr1t_l9r_go_relaxed.owl	trimethylamine N-oxide formaldehyde-lyase activity|trimethylamine-N-oxide formaldehyde-lyase (dimethylamine-forming)|trimethylamine N-oxide demethylase activity|trimethylamine N-oxide aldolase activity|trimethylamine-N-oxide formaldehyde-lyase activity				MetaCyc:TRIMETHYLAMINE-OXIDE-ALDOLASE-RXN|KEGG_REACTION:R02512|UM-BBD_reactionID:r1409|EC:4.1.2.32|RHEA:20217									molecular_function											owl:Class	
GO:0010101	biolink:NamedThing	post-embryonic root morphogenesis	The process in which the anatomical structures of the post-embryonic root are generated and organized. The post-embryonic root is the root formed after the embryonic phase has been completed.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0035595	biolink:NamedThing	N-acetylglucosaminylinositol deacetylase activity	Catalysis of the reaction: 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside + H2O = 1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside + acetate. This reaction is the hydrolysis of an acetyl group from N-acetylglucosaminylinositol.	tmpzr1t_l9r_go_relaxed.owl	1-(2-acetamido-2-deoxy-alpha-D-glucopyranosyl)-1D-myo-inositol acetylhydrolase activity|GlcNAc-Ins deacetylase activity|N-acetyl-1D-myo-inositol-2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase activity|1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside deacetylase activity				KEGG_REACTION:R09651|RHEA:26180|EC:3.5.1.103|MetaCyc:RXN1G-2			bf	2010-11-11T02:12:48Z					molecular_function											owl:Class	
GO:0140469	biolink:NamedThing	GCN2-mediated signaling	A series of reactions in which a signal is passed on to downstream proteins within the cell via GCN2 (also known as EIF2AK4), an intracellular protein kinase that is activated by stress signals, such as amino acid starvation.	tmpzr1t_l9r_go_relaxed.owl	EIF2AK4-mediated signaling|regulation of eIF2 alpha phosphorylation by amino acid starvation	https://github.com/geneontology/go-ontology/issues/15399|https://github.com/geneontology/go-ontology/issues/19153						pg	2020-05-26T08:47:25Z			GO:0060733		biological_process											owl:Class	
GO:0046334	biolink:NamedThing	octopamine catabolic process	The chemical reactions and pathways resulting in the breakdown of octopamine, 1-(p-hydroxyphenyl)-2-aminoethanol. The D enantiomer is about one-tenth as active as norepinephrine and is found in the salivary glands of Octopus and Eledone species.	tmpzr1t_l9r_go_relaxed.owl	octopamine degradation|octopamine breakdown|octopamine catabolism													biological_process											owl:Class	
GO:0061841	biolink:NamedThing	high-affinity iron exporter complex	A protein complex which transports ferrous iron (Fe(III) or Fe3+) ions from the vacuole, the main storage component of intracellular free iron, into the cytoplasm in a low iron environment.	tmpzr1t_l9r_go_relaxed.owl	FET5-FTH1 high-affinity iron exporter complex|FET5-FTH1 high affinity iron exporter complex|high affinity iron exporter complex					An example of this is FET5 in Saccharomyces cerevisiae (P43561) in PMID:9413439.								cellular_component											owl:Class	
GO:1905862	biolink:NamedThing	ferroxidase complex	A protein complex which is capable of ferroxidase activity.	tmpzr1t_l9r_go_relaxed.owl						An example of this is FET3 in Saccharomyces cerevisiae (P38993) in PMID:16522632 (inferred from direct assay).		bhm	2017-01-25T10:01:39Z					cellular_component											owl:Class	
GO:0002500	biolink:NamedThing	proteolysis within lysosome associated with antigen processing and presentation	The hydrolysis of a peptide bond or bonds within a protein by lysosomal resident proteases contributing to antigen processing and presentation.	tmpzr1t_l9r_go_relaxed.owl	lysosomal proteolysis associated with antigen processing and presentation													biological_process											owl:Class	
GO:0048831	biolink:NamedThing	regulation of shoot system development	Any process that modulates the frequency, rate or extent of shoot development.	tmpzr1t_l9r_go_relaxed.owl	regulation of shoot development													biological_process											owl:Class	
GO:0008290	biolink:NamedThing	F-actin capping protein complex	A heterodimer consisting of alpha and beta subunits that binds to and caps the barbed ends of actin filaments, thereby regulating the polymerization of actin monomers but not severing actin filaments.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0060786	biolink:NamedThing	regulation of cell differentiation involved in tissue homeostasis	Any process that modulates the frequency, rate or extent of cell differentiation that contributes to the maintenance of a steady state of a cell type within a tissue.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-07-31T01:55:19Z					biological_process											owl:Class	
GO:1901033	biolink:NamedThing	positive regulation of response to reactive oxygen species	Any process that activates or increases the frequency, rate or extent of response to reactive oxygen species.	tmpzr1t_l9r_go_relaxed.owl	up regulation of response to active oxygen species|activation of response to ROI|positive regulation of response to AOS|up regulation of response to ROI|up regulation of response to AOS|up-regulation of response to ROS|upregulation of response to reactive oxygen intermediate|up-regulation of response to AOS|activation of response to reactive oxidative species|positive regulation of response to ROI|upregulation of response to AOS|positive regulation of response to reactive oxidative species|activation of response to ROS|positive regulation of response to ROS|upregulation of response to reactive oxidative species|activation of response to reactive oxygen species|positive regulation of response to active oxygen species|up-regulation of response to reactive oxygen intermediate|upregulation of response to ROI|up-regulation of response to ROI|up-regulation of response to active oxygen species|positive regulation of response to reactive oxygen intermediate|up regulation of response to reactive oxidative species|up-regulation of response to reactive oxidative species|activation of response to reactive oxygen intermediate|up regulation of response to reactive oxygen intermediate|upregulation of response to active oxygen species|up regulation of response to reactive oxygen species|activation of response to active oxygen species|activation of response to AOS|up-regulation of response to reactive oxygen species|up regulation of response to ROS|upregulation of response to reactive oxygen species|upregulation of response to ROS							kmv	2012-06-20T07:47:35Z					biological_process											owl:Class	
GO:0043504	biolink:NamedThing	mitochondrial DNA repair	The process of restoring mitochondrial DNA after damage.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1905604	biolink:NamedThing	negative regulation of blood-brain barrier permeability	Any process that decreases blood-brain barrier permeability, the quality of the blood-brain barrier that allows for a controlled passage of substances (e.g. macromolecules, small molecules, ions) into and out of the brain.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of blood-brain barrier permeability|downregulation of blood/brain barrier permeability|inhibition of maintenance of permeability of blood-brain barrier|downregulation of BBB permeability|inhibition of maintenance of permeability of BBB|down-regulation of BBB permeability|downregulation of blood-brain barrier permeability|down-regulation of blood/brain barrier permeability|negative regulation of blood/brain barrier permeability|negative regulation of BBB permeability							als	2016-10-26T13:18:25Z					biological_process											owl:Class	
GO:0060781	biolink:NamedThing	mesenchymal cell proliferation involved in prostate gland development	The multiplication or reproduction of mesenchymal cells, resulting in the expansion of a cell population that contributes to the progression of the prostate gland over time.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-07-28T11:50:56Z					biological_process											owl:Class	
GO:1990245	biolink:NamedThing	histone H2A-T120 phosphorylation	The modification of histone H2A by the addition of a phosphate group to a threonine residue at position 120 of the histone.	tmpzr1t_l9r_go_relaxed.owl	histone H2A phosphorylation at T120|histone H2AT120 phosphorylation							sp	2013-12-04T06:41:30Z					biological_process											owl:Class	
GO:0033092	biolink:NamedThing	positive regulation of immature T cell proliferation in thymus	Any process that activates or increases the frequency, rate or extent of immature T cell proliferation in the thymus.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of thymocyte cell proliferation|positive regulation of thymocyte proliferation|positive regulation of thymic T cell proliferation													biological_process											owl:Class	
GO:0017086	biolink:NamedThing	3-methyl-2-oxobutanoate dehydrogenase (lipoamide) complex	A protein complex that catalyzes the reaction 3-methyl-2-oxobutanoate + lipoamide = S-(2-methylpropanoyl)-dihydrolipoamide + carbon dioxide (CO2). This requires thiamine diphosphate; the enzyme also acts on (S)-3-methyl-2-oxopentanoate and 4-methyl-2-oxo-pentanoate.	tmpzr1t_l9r_go_relaxed.owl	BCADH|branched-chain alpha-ketoacid dehydrogenase complex											GO:0031212		cellular_component											owl:Class	
GO:0004742	biolink:NamedThing	dihydrolipoyllysine-residue acetyltransferase activity	Catalysis of the reaction: acetyl-CoA + dihydrolipoamide = CoA + S-acetyldihydrolipoamide.	tmpzr1t_l9r_go_relaxed.owl	thioltransacetylase A activity|lipoic transacetylase activity|lipoylacetyltransferase activity|transacetylase X activity|lipoic acid acetyltransferase activity|dihydrolipoamide S-acetyltransferase activity|lipoate acetyltransferase activity|acetyl-CoA: enzyme-6-N-(dihydrolipoyl)lysine S-acetyltransferase activity|enzyme-dihydrolipoyllysine:acetyl-CoA S-acetyltransferase activity|dihydrolipoate acetyltransferase activity|dihydrolipoic transacetylase activity|lipoate transacetylase activity|acetyl-CoA:dihydrolipoamide S-acetyltransferase activity|acetyl-CoA: enzyme-N6-(dihydrolipoyl)lysine S-acetyltransferase activity|dihydrolipoyl acetyltransferase activity|lipoic acetyltransferase activity				EC:2.3.1.12									molecular_function											owl:Class	
GO:0035675	biolink:NamedThing	neuromast hair cell development	The process whose specific outcome is the progression of a neuromast hair cell over time, from its formation to the mature structure. A neuromast hair cell is a hair cell that acts as a sensory receptor of the neuromast; it is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. Cell development does not include the steps involved in committing a cell to a specific fate.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-02-14T11:01:42Z					biological_process											owl:Class	
GO:0061898	biolink:NamedThing	all-trans retinoic acid 3,4-desaturase activity	Catalysis of the reaction: all-trans-retinoic acid + 2 H(+) + O2 + 2 reduced [adrenodoxin] = all-trans-3,4-didehydro retinoic acid + 2 H2O + 2 oxidized [adrenodoxin].	tmpzr1t_l9r_go_relaxed.owl								dph	2017-06-12T15:01:23Z					molecular_function											owl:Class	
GO:2000259	biolink:NamedThing	positive regulation of protein activation cascade	Any process that activates or increases the frequency, rate or extent of protein activation cascade.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of protein activation pathway|positive regulation of protein activitory cascade							mah	2010-11-23T11:33:55Z					biological_process											owl:Class	
GO:0046318	biolink:NamedThing	negative regulation of glucosylceramide biosynthetic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glucosylceramide.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of glucosylceramide biosynthesis|negative regulation of glucosylceramide anabolism|down regulation of glucosylceramide biosynthetic process|negative regulation of glucosylceramide synthesis|downregulation of glucosylceramide biosynthetic process|inhibition of glucosylceramide biosynthetic process|down-regulation of glucosylceramide biosynthetic process|negative regulation of glucosylceramide formation													biological_process											owl:Class	
GO:0038182	biolink:NamedThing	G protein-coupled bile acid receptor activity	Combining with an extracellular bile acid and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.	tmpzr1t_l9r_go_relaxed.owl	membrane bile acid receptor activity|cell surface bile acid receptor|G-protein coupled bile acid receptor activity				Wikipedia:G_protein-coupled_bile_acid_receptor			bf	2013-05-16T10:29:42Z					molecular_function											owl:Class	
GO:0050248	biolink:NamedThing	Renilla-luciferin 2-monooxygenase activity	Catalysis of the reaction: Renilla luciferin + O2 = oxidized Renilla luciferin + CO2 + light.	tmpzr1t_l9r_go_relaxed.owl	Renilla-luciferin:oxygen 2-oxidoreductase (decarboxylating)|luciferase activity|Renilla-type luciferase activity|luciferase (Renilla luciferin)|aequorin activity				MetaCyc:RENILLA-LUCIFERIN-2-MONOOXYGENASE-RXN|RHEA:14765|EC:1.13.12.5									molecular_function											owl:Class	
GO:2000469	biolink:NamedThing	negative regulation of peroxidase activity	Any process that stops, prevents or reduces the frequency, rate or extent of peroxidase activity.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of oxyperoxidase activity|negative regulation of peroxidase reaction|negative regulation of donor:hydrogen-peroxide oxidoreductase activity							bf	2011-03-08T02:18:59Z					biological_process											owl:Class	
GO:0071060	biolink:NamedThing	alpha7-beta1 integrin-CD151 complex	A protein complex that consists of an alpha7-beta1 integrin complex bound to the tetraspanin CD151.	tmpzr1t_l9r_go_relaxed.owl	ITGA7-ITGB1-CD151 complex							mah	2009-11-03T04:02:01Z					cellular_component											owl:Class	
GO:0003425	biolink:NamedThing	establishment of mitotic spindle orientation involved in growth plate cartilage chondrocyte division	A cell cycle process that sets the alignment of mitotic spindle relative to other cellular structures and contributes to oriented chondrocyte division in the growth plate.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-12-22T10:36:36Z					biological_process											owl:Class	
GO:0003426	biolink:NamedThing	cytoskeleton polarization involved in growth plate cartilage chondrocyte division	A process that is carried out at the cellular level which results in the polarization of cytoskeletal structures in a growth plate cartilage chondrocyte. This process results in the oriented division of the cell.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-12-22T11:38:22Z					biological_process											owl:Class	
GO:1900943	biolink:NamedThing	positive regulation of (Z)-nonadeca-1,14-diene biosynthetic process	Any process that activates or increases the frequency, rate or extent of (Z)-nonadeca-1,14-diene biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	activation of (Z)-nonadeca-1,14-diene synthesis|up-regulation of (Z)-nonadeca-1,14-diene biosynthesis|activation of (Z)-nonadeca-1,14-diene biosynthetic process|up regulation of (Z)-nonadeca-1,14-diene anabolism|upregulation of (Z)-nonadeca-1,14-diene biosynthetic process|upregulation of (Z)-nonadeca-1,14-diene biosynthesis|activation of (Z)-nonadeca-1,14-diene formation|activation of (Z)-nonadeca-1,14-diene anabolism|positive regulation of (Z)-nonadeca-1,14-diene biosynthesis|upregulation of (Z)-nonadeca-1,14-diene synthesis|activation of (Z)-nonadeca-1,14-diene biosynthesis|up regulation of (Z)-nonadeca-1,14-diene synthesis|up-regulation of (Z)-nonadeca-1,14-diene anabolism|up-regulation of (Z)-nonadeca-1,14-diene synthesis|up-regulation of (Z)-nonadeca-1,14-diene biosynthetic process|up regulation of (Z)-nonadeca-1,14-diene formation|up regulation of (Z)-nonadeca-1,14-diene biosynthesis|up regulation of (Z)-nonadeca-1,14-diene biosynthetic process|positive regulation of (Z)-nonadeca-1,14-diene synthesis|up-regulation of (Z)-nonadeca-1,14-diene formation|upregulation of (Z)-nonadeca-1,14-diene anabolism|positive regulation of (Z)-nonadeca-1,14-diene anabolism|upregulation of (Z)-nonadeca-1,14-diene formation|positive regulation of (Z)-nonadeca-1,14-diene formation							tt	2012-06-14T03:18:01Z					biological_process											owl:Class	
GO:1905267	biolink:NamedThing	endonucleolytic cleavage involved in tRNA processing	Any endonucleolytic RNA phosphodiester bond hydrolysis that is involved in tRNA processing.	tmpzr1t_l9r_go_relaxed.owl	RNA phosphodiester bond hydrolysis, endonucleolytic involved in tRNA maturation							al	2016-06-14T14:54:54Z					biological_process											owl:Class	
GO:0046526	biolink:NamedThing	D-xylulose reductase activity	Catalysis of the reaction: NAD(+) + xylitol = D-xylulose + H(+) + NADH.	tmpzr1t_l9r_go_relaxed.owl	xylitol dehydrogenase activity				RHEA:20433|EC:1.1.1.9|Reactome:R-HSA-5662471|MetaCyc:D-XYLULOSE-REDUCTASE-RXN|KEGG_REACTION:R01896									molecular_function											owl:Class	
GO:0031320	biolink:NamedThing	hexitol dehydrogenase activity	Catalysis of the reaction: hexitol + acceptor = hexose + reduced acceptor.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0071471	biolink:NamedThing	cellular response to non-ionic osmotic stress	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of non-ionic solutes (e.g. mannitol, sorbitol) in the environment.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-12-18T11:47:59Z					biological_process											owl:Class	
GO:0035873	biolink:NamedThing	lactate transmembrane transport	The process in which lactate is transported across a membrane. Lactate is 2-hydroxypropanoate, CH3-CHOH-COOH; L(+)-lactate is formed by anaerobic glycolysis in animal tissues, and DL-lactate is found in sour milk, molasses and certain fruit juices.	tmpzr1t_l9r_go_relaxed.owl	lactate membrane transport					Note that this term is not intended for use in annotating lateral movement within membranes.		bf	2011-05-31T09:26:59Z					biological_process											owl:Class	
GO:0047693	biolink:NamedThing	ATP diphosphatase activity	Catalysis of the reaction: ATP + H2O = AMP + diphosphate.	tmpzr1t_l9r_go_relaxed.owl	adenosine triphosphate pyrophosphatase activity|ATP diphosphohydrolase|ATP pyrophosphatase activity|ATP diphosphohydrolase (diphosphate-forming)				MetaCyc:ATP-PYROPHOSPHATASE-RXN|RHEA:14245|EC:3.6.1.8									molecular_function											owl:Class	
GO:0007615	biolink:NamedThing	anesthesia-resistant memory	The memory process that results in the formation of consolidated memory resistant to disruption of the patterned activity of the brain, without requiring protein synthesis.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1900354	biolink:NamedThing	regulation of methanofuran metabolic process	Any process that modulates the frequency, rate or extent of methanofuran metabolic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of methanofuran metabolism							tt	2012-04-06T02:15:44Z					biological_process											owl:Class	
GO:0061983	biolink:NamedThing	meiosis II cell cycle process	A process that coontributes to the second meiotic division. The second meiotic division separates chromatids resulting in a haploid number of chromosomes.	tmpzr1t_l9r_go_relaxed.owl	second meiotic division							dph	2018-02-14T22:37:44Z					biological_process											owl:Class	
GO:0061038	biolink:NamedThing	uterus morphogenesis	The process in which anatomical structures of the uterus are generated and organized.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-02-22T11:12:35Z					biological_process											owl:Class	
GO:0039505	biolink:NamedThing	suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II	Any viral process that inhibits a host antigen-presenting cell expressing a peptide antigen on its cell surface in association with an MHC class II protein complex.	tmpzr1t_l9r_go_relaxed.owl	inhibition of host MHC class II molecule presentation by virus				VZ:820			bf	2011-06-02T02:34:51Z					biological_process											owl:Class	
GO:0046352	biolink:NamedThing	disaccharide catabolic process	The chemical reactions and pathways resulting in the breakdown of disaccharides, sugars composed of two monosaccharide units.	tmpzr1t_l9r_go_relaxed.owl	disaccharide catabolism|disaccharide breakdown|disaccharide degradation													biological_process											owl:Class	
GO:0016153	biolink:NamedThing	urocanate hydratase activity	Catalysis of the reaction: 4-imidazolone-5-propanoate + H(+) = trans-urocanate + H(2)O.	tmpzr1t_l9r_go_relaxed.owl	3-(5-oxo-4,5-dihydro-3H-imidazol-4-yl)propanoate hydro-lyase activity|urocanase activity|imidazolonepropionate hydrolase activity|3-(5-oxo-4,5-dihydro-3H-imidazol-4-yl)propanoate hydro-lyase (urocanate-forming)				MetaCyc:UROCANATE-HYDRATASE-RXN|KEGG_REACTION:R02914|RHEA:13101|Reactome:R-HSA-70903|EC:4.2.1.49									molecular_function											owl:Class	
GO:1901164	biolink:NamedThing	negative regulation of trophoblast cell migration	Any process that stops, prevents or reduces the frequency, rate or extent of trophoblast cell migration.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of trophoblast cell migration|inhibition of trophoblast cell migration|down regulation of trophoblast cell migration|downregulation of trophoblast cell migration							vk	2012-07-19T07:53:28Z					biological_process											owl:Class	
GO:2000352	biolink:NamedThing	negative regulation of endothelial cell apoptotic process	Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell apoptotic process.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of programmed cell death, endothelial cells|negative regulation of programmed cell death of endothelial cells by apoptosis|negative regulation of endothelial cell apoptosis|negative regulation of endothelial cell programmed cell death by apoptosis|negative regulation of apoptosis of endothelial cells|negative regulation of killing of endothelial cells							mah	2011-02-03T10:43:20Z					biological_process											owl:Class	
GO:0080014	biolink:NamedThing	thalianol hydroxylase activity	Catalysis of the reaction: a thalianol = a thalian-diol. This reaction is the addition of a hydroxyl group to thalianol ((13R,14R,17E)-podioda-8,17,21-trien-3beta-ol) to create a thalian-diol ((13R,14R,17E)-podioda-8,17,21-trien-3beta,X-diol), where the hydroxyl group may be attached at one of several different available carbons in ring B or C of thalianol, indicated by the X.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-9631|EC:1.14.13.-	In Field and Osbourn 2008 (PMID:18356490), thalianol is referred to as (3S,13S,3R)-malabarica-8,17,21-trien-3-ol and thalian-diol is referred to as (3S,13S,14R)-malabarica-8,17,21-trien-3,?-diol, but the error in this naming system was pointed out in Kolesnikova 2007 (PMID:17474751). The new names used in the definition have been approved by the authors (Field and Osbourn 2008).								molecular_function											owl:Class	
GO:0004360	biolink:NamedThing	glutamine-fructose-6-phosphate transaminase (isomerizing) activity	Catalysis of the reaction: beta-D-fructose 6-phosphate + L-glutamine = D-glucosamine 6-phosphate + L-glutamate.	tmpzr1t_l9r_go_relaxed.owl	hexosephosphate aminotransferase activity|L-glutamine-D-fructose-6-phosphate amidotransferase activity|glucosamine--fructose-6-phosphate aminotransferase (isomerizing) activity|GlcN6P synthase activity|glucosaminephosphate isomerase|D-fructose-6-phosphate amidotransferase activity|glucosamine-6-phosphate isomerase (glutamine-forming) activity|L-glutamine:D-fructose-6-phosphate isomerase (deaminating)|glucosamine 6-phosphate synthase activity|glucosamine-6-phosphate synthase activity				KEGG_REACTION:R00768|Reactome:R-HSA-4085027|Reactome:R-HSA-449715|RHEA:13237|EC:2.6.1.16|MetaCyc:L-GLN-FRUCT-6-P-AMINOTRANS-RXN									molecular_function											owl:Class	
GO:0070548	biolink:NamedThing	L-glutamine aminotransferase activity	Catalysis of the transfer of an amino group from L-glutamine to an acceptor, usually a 2-oxo acid.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0043319	biolink:NamedThing	positive regulation of cytotoxic T cell degranulation	Any process that activates or increases the frequency, rate or extent of cytotoxic T cell degranulation.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of cytotoxic T cell granule exocytosis|positive regulation of cytotoxic T-lymphocyte granule exocytosis|stimulation of cytotoxic T cell degranulation|activation of cytotoxic T cell degranulation|positive regulation of cytotoxic T lymphocyte degranulation|positive regulation of cytotoxic T-cell degranulation|positive regulation of cytotoxic T-cell granule exocytosis|positive regulation of cytotoxic T lymphocyte granule exocytosis|upregulation of cytotoxic T cell degranulation|up regulation of cytotoxic T cell degranulation|positive regulation of cytotoxic T-lymphocyte degranulation|up-regulation of cytotoxic T cell degranulation													biological_process											owl:Class	
GO:0102545	biolink:NamedThing	phosphatidyl phospholipase B activity	Catalysis of the reaction: 2 H2O + a phosphatidylcholine = sn-glycero-3-phosphocholine + 2 H+ + 2 a carboxylate.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-14899|EC:3.1.1.5									molecular_function											owl:Class	
GO:1990522	biolink:NamedThing	tail spike morphogenesis	The process in which the nematode tail spike is generated and organized. An example of this process is seen in C. elegans, where the tapered tail spike is formed during embryogenesis by a filamentous process that passes posteriorly through hyp10, the tail ventral hypodermis; the filamentous process is formed by a binucleate cell, the tail-spike cell, that subsequently undergoes programmed cell death.	tmpzr1t_l9r_go_relaxed.owl					WBbt:0008072|WBbt:0006979			jl	2014-10-23T15:20:15Z					biological_process											owl:Class	
GO:1905607	biolink:NamedThing	negative regulation of presynapse assembly	Any process that stops, prevents or reduces the frequency, rate or extent of presynapse assembly.	tmpzr1t_l9r_go_relaxed.owl	downregulation of presynapse assembly|inhibition of presynapse biogenesis|down-regulation of presynapse assembly|downregulation of presynapse biogenesis|down regulation of presynapse biogenesis|inhibition of presynaptic terminal assembly|downregulation of presynaptic terminal assembly|down-regulation of presynaptic terminal assembly|down-regulation of presynapse biogenesis|down regulation of presynapse assembly|inhibition of presynapse assembly|negative regulation of presynapse biogenesis|negative regulation of presynaptic terminal assembly|down regulation of presynaptic terminal assembly							bc	2016-10-27T16:08:20Z					biological_process											owl:Class	
GO:1900088	biolink:NamedThing	regulation of inositol biosynthetic process	Any process that modulates the frequency, rate or extent of inositol biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of inositol synthesis|regulation of inositol anabolism|regulation of myo-inositol biosynthetic process|regulation of inositol formation|regulation of vitamin Bh biosynthesis|regulation of myo-inositol biosynthesis|regulation of inositol biosynthesis|regulation of vitamin Bh biosynthetic process							dhl	2012-02-08T06:27:11Z					biological_process											owl:Class	
GO:0002099	biolink:NamedThing	tRNA wobble guanine modification	The process in which a guanine in t position 34 of a tRNA is post-transcriptionally modified.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0016092	biolink:NamedThing	prenol catabolic process	The chemical reactions and pathways resulting in the breakdown of prenols, isoprenoids of general formula (H-CH2-C(CH3)=CH-CH2-)n-OH, any primary monohydroxy alcohol whose carbon skeleton consists of two or more isoprenoid residues linked head to tail.	tmpzr1t_l9r_go_relaxed.owl	prenol degradation|prenol catabolism|prenol breakdown													biological_process											owl:Class	
GO:0045677	biolink:NamedThing	negative regulation of R7 cell differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of R7cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of R7 differentiation|negative regulation of R7 differentiation|inhibition of R7 differentiation|down regulation of R7 differentiation|downregulation of R7 differentiation													biological_process											owl:Class	
GO:0021957	biolink:NamedThing	corticospinal tract morphogenesis	Generation of a long process of a pyramidal cell, that carries efferent (outgoing) action potentials from the cell body in cerebral cortex layer V towards target cells in the gray matter of the spinal cord. This axonal process is a member of those that make up the corticospinal tract.	tmpzr1t_l9r_go_relaxed.owl	corticospinal tract axonogenesis|CST axonogenesis													biological_process											owl:Class	
GO:0061339	biolink:NamedThing	establishment or maintenance of monopolar cell polarity	Any cellular process that results in the specification, formation or maintenance of monopolar intracellular organization or cell growth patterns. Monopolar cell organization is directional organization along an axis.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-09-29T09:10:05Z					biological_process											owl:Class	
GO:1900739	biolink:NamedThing	regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway	Any process that modulates the frequency, rate or extent of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	regulation of protein insertion into mitochondrial membrane involved in induction of apoptosis|regulation of protein insertion into mitochondrion membrane during induction of apoptosis|regulation of protein insertion into mitochondrial membrane during induction of apoptosis|regulation of insertion of proteins into mitochondrial membranes during the induction of apoptosis							pr	2012-05-28T02:28:18Z					biological_process											owl:Class	
GO:0008693	biolink:NamedThing	3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity	Catalysis of the reaction: (3R)-3-hydroxydecanoyl-[acyl-carrier protein] = 2,3-decenoyl-[acyl-carrier protein] or 3,4-decenoyl-[acyl-carrier protein] + H2O.	tmpzr1t_l9r_go_relaxed.owl	beta-hydroxydecanoyl thioester dehydrase activity|beta-hydroxydecanoate dehydrase activity|beta-hydroxyacyl-ACP dehydrase activity|3-hydroxydecanoyl-acyl-carrier-protein dehydratase activity|D-3-hydroxydecanoyl-acyl-carrier-protein dehydratase activity|beta-hydroxydecanoyl thiol ester dehydrase activity|HDDase activity|FabA|3-hydroxydecanoyl-acyl carrier protein dehydratase activity|beta-hydroxyacyl-acyl carrier protein dehydratase activity|3-hydroxydecanoyl-[acyl-carrier protein] dehydratase activity|3-hydroxydecanoyl-acyl carrier protein dehydrase activity|3-hydroxydecanoyl-ACP dehydratase activity|D-3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity|(3R)-3-hydroxydecanoyl-acyl-carrier-protein hydro-lyase activity				RHEA:41860|EC:4.2.1.59									molecular_function											owl:Class	
GO:0032592	biolink:NamedThing	integral component of mitochondrial membrane	The component of the mitochondrial membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.	tmpzr1t_l9r_go_relaxed.owl	integral to mitochondrial membrane													cellular_component											owl:Class	
GO:0010258	biolink:NamedThing	NADH dehydrogenase complex (plastoquinone) assembly	The aggregation, arrangement and bonding together of a set of components to form NADH:plastoquinone dehydrogenase complex, which is involved in the non-photochemical reduction of plastoquinones, as well as the cyclic electron transport around photosystem I.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0002234	biolink:NamedThing	detection of endoplasmic reticulum overloading	The series of events in which a stimulus generated by the accumulation of normal or misfolded proteins in the endoplasmic reticulum is received and converted into a molecular signal.	tmpzr1t_l9r_go_relaxed.owl	detection of ER overloading													biological_process											owl:Class	
GO:0030473	biolink:NamedThing	nuclear migration along microtubule	The directed movement of the nucleus along microtubules within the cell, mediated by motor proteins.	tmpzr1t_l9r_go_relaxed.owl	transport of nucleus by microtubules|microtubule-dependent nuclear positioning|nuclear movement, microtubule-mediated|microtubule-mediated nuclear migration|transport of nucleus, microtubule-mediated|microtubule cytoskeleton-dependent nucleus positioning|nucleus migration|microtubule-dependent nucleus positioning|nuclear migration, microtubule-mediated|microtubule cytoskeleton-dependent nuclear positioning											GO:0000065		biological_process											owl:Class	
GO:0043038	biolink:NamedThing	amino acid activation	The modification of an amino acid to an active form, for incorporation into a peptide, protein or other macromolecule.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0051325	biolink:NamedThing	interphase	The cell cycle phase following cytokinesis which begins with G1 phase, proceeds through S phase and G2 phase and ends when prophase of meiosis or mitosis begins. During interphase the cell readies itself for meiosis or mitosis and the replication of its DNA occurs.	tmpzr1t_l9r_go_relaxed.owl	karyostasis|resting phase				Wikipedia:Interphase	Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).								biological_process											owl:Class	
GO:0110155	biolink:NamedThing	NAD-cap decapping	Cleavage of the 5'-NAD-cap of an RNA. The NAD-cap is present at the 5'-end of some RNAs in both bacetria and eukaryotes. While it promotes RNA stability in bacteria, it promotes RNA decay in eukaryotes.	tmpzr1t_l9r_go_relaxed.owl								kmv	2019-07-08T17:27:56Z					biological_process											owl:Class	
GO:0110154	biolink:NamedThing	RNA decapping	Cleavage of the 5'-cap of an RNA.	tmpzr1t_l9r_go_relaxed.owl								kmv	2019-07-08T17:23:59Z					biological_process											owl:Class	
GO:0043852	biolink:NamedThing	monomethylamine methyltransferase activity	Catalysis of the reaction: monomethylamine + a monomethylamine corrinoid protein = a methylated monomethylamine corrinoid protein + NH3.	tmpzr1t_l9r_go_relaxed.owl	monomethylamine:corrinoid methyltransferase activity|MtmB|MMAMT				RHEA:26059|MetaCyc:RXN-8098|EC:2.1.1.248	This function is the first step in the pathway of methanogenesis from monomethylamine.								molecular_function											owl:Class	
GO:0019147	biolink:NamedThing	(R)-aminopropanol dehydrogenase activity	Catalysis of the reaction: (R)-1-aminopropan-2-ol + NAD(+) = aminoacetone + H(+) + NADH.	tmpzr1t_l9r_go_relaxed.owl	1-aminopropan-2-ol-dehydrogenase activity|L-aminopropanol dehydrogenase activity|DL-1-aminopropan-2-ol: NAD+ dehydrogenase activity|(R)-1-aminopropan-2-ol:NAD+ oxidoreductase activity|1-aminopropan-2-ol-NAD+ dehydrogenase activity|L(+)-1-aminopropan-2-ol:NAD+ oxidoreductase activity|L(+)-1-aminopropan-2-ol-NAD/NADP oxidoreductase activity				MetaCyc:AMINOPROPDEHYDROG-RXN|RHEA:16517|EC:1.1.1.75|KEGG_REACTION:R03759									molecular_function											owl:Class	
GO:2000857	biolink:NamedThing	positive regulation of mineralocorticoid secretion	Any process that activates or increases the frequency, rate or extent of mineralocorticoid secretion.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-07-26T08:46:45Z					biological_process											owl:Class	
GO:1900481	biolink:NamedThing	negative regulation of diacylglycerol biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of diacylglycerol biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	inhibition of diacylglycerol anabolism|down-regulation of diacylglycerol biosynthesis|inhibition of diacylglycerol synthesis|downregulation of diacylglycerol biosynthesis|downregulation of diacylglycerol anabolism|downregulation of diacylglycerol synthesis|negative regulation of diacylglycerol formation|inhibition of diacylglycerol biosynthetic process|negative regulation of diacylglycerol anabolism|inhibition of diacylglycerol biosynthesis|down-regulation of diacylglycerol anabolism|down regulation of diacylglycerol biosynthesis|downregulation of diacylglycerol biosynthetic process|down-regulation of diacylglycerol biosynthetic process|down regulation of diacylglycerol formation|down-regulation of diacylglycerol synthesis|down regulation of diacylglycerol biosynthetic process|down regulation of diacylglycerol anabolism|negative regulation of diacylglycerol biosynthesis|down-regulation of diacylglycerol formation|inhibition of diacylglycerol formation|down regulation of diacylglycerol synthesis|negative regulation of diacylglycerol synthesis|downregulation of diacylglycerol formation							al	2012-05-02T10:09:09Z					biological_process											owl:Class	
GO:0009843	biolink:NamedThing	cyanelle thylakoid	A thylakoid found in a cyanelle, which is a type of plastid found in certain algae. The cyanelle contains a photosynthetic membrane resembling that of cyanobacteria.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0005712	biolink:NamedThing	chiasma	A connection formed between chromatids, visible during meiosis, thought to be the point of the interchange involved in crossing-over.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Chiasma_(genetics)									cellular_component											owl:Class	
GO:1900794	biolink:NamedThing	terrequinone A metabolic process	The chemical reactions and pathways involving terrequinone A.	tmpzr1t_l9r_go_relaxed.owl	terrequinone A metabolism							di	2012-06-04T09:45:20Z					biological_process											owl:Class	
GO:1902233	biolink:NamedThing	negative regulation of positive thymic T cell selection	Any process that stops, prevents or reduces the frequency, rate or extent of positive thymic T cell selection.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of positive thymic T-lymphocyte selection|down-regulation of positive thymic T cell selection|inhibition of positive thymic T-cell selection|down-regulation of positive thymic T lymphocyte selection|down-regulation of positive thymic T-cell selection|inhibition of positive thymic T-lymphocyte selection|negative regulation of positive thymic T-cell selection|down regulation of positive thymic T lymphocyte selection|downregulation of positive thymic T-cell selection|downregulation of positive thymic T lymphocyte selection|down-regulation of positive thymic T-lymphocyte selection|inhibition of positive thymic T cell selection|down regulation of positive thymic T-cell selection|down regulation of positive thymic T-lymphocyte selection|downregulation of positive thymic T cell selection|inhibition of positive thymic T lymphocyte selection|downregulation of positive thymic T-lymphocyte selection|negative regulation of positive thymic T lymphocyte selection|down regulation of positive thymic T cell selection							lb	2013-06-14T11:19:15Z					biological_process											owl:Class	
GO:0008424	biolink:NamedThing	glycoprotein 6-alpha-L-fucosyltransferase activity	Catalysis of the reaction: N(4)-{N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->6)]-beta-D-mannosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl}-L-asparagine + GDP-L-fucose = N(4)-{N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->6)]-beta-D-mannosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-[alpha-L-fucosyl-(1->6)]-N-acetyl-beta-D-glucosaminyl}asparagine + GDP + H(+).	tmpzr1t_l9r_go_relaxed.owl	GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha(1->6)fucosyltransferase activity|GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha-(1->6)fucosyltransferase activity|glycoprotein fucosyltransferase activity|GDP-fucose--glycoprotein fucosyltransferase activity|FucT|guanosine diphosphofucose--glycoprotein fucosyltransferase activity|GDP-L-fucose--glycoprotein fucosyltransferase activity|GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha(1,6)fucosyltransferase activity|GDPfucose-glycoprotein fucosyltransferase activity|GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha-(1,6)fucosyltransferase activity				EC:2.4.1.68|Reactome:R-HSA-9696980|Reactome:R-HSA-1028788|RHEA:12985|MetaCyc:2.4.1.68-RXN|KEGG_REACTION:R05988									molecular_function											owl:Class	
GO:0031642	biolink:NamedThing	negative regulation of myelination	Any process that stops, prevents, or reduces the frequency, rate or extent of the formation of a myelin sheath around nerve axons.	tmpzr1t_l9r_go_relaxed.owl	downregulation of myelination|down-regulation of myelination|inhibition of myelination|down regulation of myelination													biological_process											owl:Class	
GO:0018706	biolink:NamedThing	pyrogallol hydroxytransferase activity	Catalysis of the reaction: 1,2,3,5-tetrahydroxybenzene + 1,2,3-trihydroxybenzene = 1,3,5-trihydroxybenzene + 1,2,3,5-tetrahydroxybenzene.	tmpzr1t_l9r_go_relaxed.owl	1,2,3,5-tetrahydroxybenzene-pyrogallol hydroxyltransferase (transhydroxylase)|transhydroxylase activity|pyrogallol hydroxyltransferase activity|1,2,3,5-tetrahydroxybenzene hydroxyltransferase activity|1,2,3,5-tetrahydroxybenzene:1,2,3-trihydroxybenzene hydroxyltransferase activity|1,2,3,5-tetrahydroxybenzene:1,2,3-trihydroxybenzene hydroxytransferase activity|1,2,3,5-tetrahydroxybenzene:pyrogallol transhydroxylase activity				RHEA:21000|UM-BBD_reactionID:r0006|MetaCyc:1.97.1.2-RXN|EC:1.97.1.2									molecular_function											owl:Class	
GO:1900995	biolink:NamedThing	ubiquinone-6 binding	Binding to ubiquinone-6. Ubiquinone-6 is a ubiquinone compound having a (2E,6E,10E,14E,18E)-3,7,11,15,19,23-hexamethyltetracosa-2,6,10,14,18,22-hexaen-1-yl substituent at position 2.	tmpzr1t_l9r_go_relaxed.owl								bf	2012-06-14T02:49:15Z					molecular_function											owl:Class	
GO:0048039	biolink:NamedThing	ubiquinone binding	Binding to ubiquinone, a quinone derivative with a tail of isoprene units.	tmpzr1t_l9r_go_relaxed.owl	coenzyme Q binding|coenzyme Q6 binding													molecular_function											owl:Class	
GO:0021598	biolink:NamedThing	abducens nerve morphogenesis	The process in which the anatomical structure of the abducens nerve is generated and organized. The motor function of the abducens nerve is to contract the lateral rectus which results in abduction of the eye.	tmpzr1t_l9r_go_relaxed.owl	CN VI development													biological_process											owl:Class	
GO:0047167	biolink:NamedThing	1-alkyl-2-acetylglycerol O-acyltransferase activity	Catalysis of the reaction: 1-O-alkyl-2-acetyl-sn-glycerol + acyl-CoA = 1-O-alkyl-2-acetyl-3-acyl-sn-glycerol + CoA.	tmpzr1t_l9r_go_relaxed.owl	1-hexadecyl-2-acetylglycerol acyltransferase activity|acyl-CoA:1-O-alkyl-2-acetyl-sn-glycerol O-acyltransferase activity				EC:2.3.1.125|RHEA:21996|MetaCyc:2.3.1.125-RXN									molecular_function											owl:Class	
GO:0051938	biolink:NamedThing	L-glutamate import	The directed movement of L-glutamate, the L-enantiomer of the anion of 2-aminopentanedioic acid, into a cell or organelle.	tmpzr1t_l9r_go_relaxed.owl	L-glutamate uptake													biological_process											owl:Class	
GO:1901964	biolink:NamedThing	positive regulation of cell proliferation involved in outflow tract morphogenesis	Any process that activates or increases the frequency, rate or extent of cell proliferation involved in outflow tract morphogenesis.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of cell proliferation involved in outflow tract morphogenesis|upregulation of cell proliferation involved in outflow tract morphogenesis|up regulation of cell proliferation involved in outflow tract morphogenesis|activation of cell proliferation involved in outflow tract morphogenesis							dph	2013-02-20T20:30:31Z					biological_process											owl:Class	
GO:0032016	biolink:NamedThing	negative regulation of Ran protein signal transduction	Any process that stops, prevents, or reduces the frequency, rate or extent of Ran protein signal transduction.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of Ran protein signal transduction|downregulation of Ran protein signal transduction|inhibition of Ran protein signal transduction|down regulation of Ran protein signal transduction													biological_process											owl:Class	
GO:0047402	biolink:NamedThing	protein-glucosylgalactosylhydroxylysine glucosidase activity	Catalysis of the reaction: H2O + protein alpha-D-glucosyl-1,2-beta-D-galactosyl-L-hydroxylysine = protein beta-D-galactosyl-L-hydroxylysine + beta-D-glucose. The enzyme specifically hydrolyzes glucose from alpha-D-glucosyl- (1->2)-beta-D-galactosyl disaccharide units that are linked to hydroxylysine residues of collagen and collagen-like proteins.	tmpzr1t_l9r_go_relaxed.owl	protein-alpha-D-glucosyl-1,2-beta-D-galactosyl-L-hydroxylysine glucohydrolase activity|2-O-alpha-D-glucopyranosyl-5-O-alpha-D-galactopyranosylhydroxy-L-lysine glucohydrolase activity				RHEA:11068|EC:3.2.1.107|MetaCyc:3.2.1.107-RXN									molecular_function											owl:Class	
GO:0016746	biolink:NamedThing	acyltransferase activity	Catalysis of the transfer of an acyl group from one compound (donor) to another (acceptor).	tmpzr1t_l9r_go_relaxed.owl	transferase activity, transferring acyl groups	https://github.com/geneontology/go-ontology/issues/20486			EC:2.3.-.-|Reactome:R-HSA-8858298|Reactome:R-HSA-193491|Reactome:R-HSA-6792572|Reactome:R-HSA-159431|Reactome:R-HSA-192312							GO:0008415		molecular_function											owl:Class	
GO:0051070	biolink:NamedThing	galactomannan biosynthetic process	The chemical reactions and pathways resulting in the formation of galactomannan, a polysaccharide composed of D-galactosyl and D-mannosyl. The mannosyl units form the backbone structure (a linear main chain) with the D-galactosyl as single side units.	tmpzr1t_l9r_go_relaxed.owl	galactomannan biosynthesis|galactomannan synthesis|galactomannan formation|galactomannan anabolism													biological_process											owl:Class	
GO:0070403	biolink:NamedThing	NAD+ binding	Binding to the oxidized form, NAD, of nicotinamide adenine dinucleotide, a coenzyme involved in many redox and biosynthetic reactions.	tmpzr1t_l9r_go_relaxed.owl	NAD binding|NAD (oxidized) binding|oxidized NAD binding|oxidized nicotinamide adenine dinucleotide binding													molecular_function											owl:Class	
GO:0051287	biolink:NamedThing	NAD binding	Binding to nicotinamide adenine dinucleotide, a coenzyme involved in many redox and biosynthetic reactions; binding may be to either the oxidized form, NAD+, or the reduced form, NADH.	tmpzr1t_l9r_go_relaxed.owl	NAD+ or NADH binding|nicotinamide adenine dinucleotide binding|NAD or NADH binding											GO:0051288		molecular_function											owl:Class	
GO:0120259	biolink:NamedThing	7SK snRNP	A ribonucleoprotein complex that contains the 7SK snRNA. The 7SK snRNP plays a central role in RNA polymerase II elongation control by regulating the availability of active P-TEFb.	tmpzr1t_l9r_go_relaxed.owl	snRNP 7SK	https://github.com/geneontology/go-ontology/issues/19981						krc	2020-09-15T22:01:31Z					cellular_component											owl:Class	
GO:1901793	biolink:NamedThing	3-(3-hydroxyphenyl)propanoate metabolic process	The chemical reactions and pathways involving 3-(3-hydroxyphenyl)propanoate.	tmpzr1t_l9r_go_relaxed.owl	3-(3-hydroxyphenyl)propanoate metabolism							yaf	2013-01-16T11:47:09Z					biological_process											owl:Class	
GO:0106030	biolink:NamedThing	neuron projection fasciculation	The collection of neuronal projections into a bundle of rods, known as a fascicle.	tmpzr1t_l9r_go_relaxed.owl								hjd	2017-06-26T19:43:23Z					biological_process											owl:Class	
GO:0043040	biolink:NamedThing	tRNA aminoacylation for nonribosomal peptide biosynthetic process	The synthesis of aminoacyl tRNA by the formation of an ester bond between the 3'-hydroxyl group of the most 3' adenosine of the tRNA, to be used in nonribosomal peptide synthesis.	tmpzr1t_l9r_go_relaxed.owl	tRNA aminoacylation for nonribosomal peptide biosynthesis|tRNA aminoacylation for nonribosomal peptide formation|tRNA aminoacylation for nonribosomal peptide synthesis|tRNA aminoacylation for nonribosomal peptide anabolism													biological_process											owl:Class	
GO:0043039	biolink:NamedThing	tRNA aminoacylation	The chemical reactions and pathways by which the various amino acids become bonded to their corresponding tRNAs. The most common route for synthesis of aminoacyl tRNA is by the formation of an ester bond between the 3'-hydroxyl group of the most 3' adenosine of the tRNA and the alpha carboxylic acid  group of an amino acid, usually catalyzed by the cognate aminoacyl-tRNA ligase. A given aminoacyl-tRNA ligase aminoacylates all species of an isoaccepting group of tRNA molecules.	tmpzr1t_l9r_go_relaxed.owl	tRNA charging|aminoacyl-tRNA biosynthetic process|aminoacyl-tRNA biosynthesis													biological_process											owl:Class	
GO:0072695	biolink:NamedThing	regulation of DNA recombination at telomere	Any process that modulates the frequency, rate or extent of DNA recombination within the telomere.	tmpzr1t_l9r_go_relaxed.owl	regulation of telomeric recombination							mah	2012-04-03T10:31:50Z					biological_process											owl:Class	
GO:1903509	biolink:NamedThing	liposaccharide metabolic process	The chemical reactions and pathways involving liposaccharide.	tmpzr1t_l9r_go_relaxed.owl	liposaccharide metabolism							dph	2014-10-01T21:52:52Z					biological_process											owl:Class	
GO:0007564	biolink:NamedThing	regulation of chitin-based cuticle tanning	Any process that modulates the frequency, rate or extent of chitin-based cuticular tanning.	tmpzr1t_l9r_go_relaxed.owl	regulation of cuticle tanning|regulation of cuticle hardening													biological_process											owl:Class	
GO:0031884	biolink:NamedThing	type 1 member 1 taste receptor binding	Binding to a type 1 member 1 taste receptor.	tmpzr1t_l9r_go_relaxed.owl	type 1 member 1 taste receptor ligand													molecular_function											owl:Class	
GO:0031883	biolink:NamedThing	taste receptor binding	Binding to a taste receptor.	tmpzr1t_l9r_go_relaxed.owl	taste receptor ligand													molecular_function											owl:Class	
GO:0001039	biolink:NamedThing	RNA polymerase III hybrid type promoter sequence-specific DNA binding	Binding to a sequence of DNA that is a part of a hybrid type promoter that controls transcription by RNA polymerase III (Pol III). A hybrid Pol III promoter contains both regulatory elements both upstream and downstream of the transcription initiation site. An example gene with such a promoter is the S. cerevisiae U6 gene.	tmpzr1t_l9r_go_relaxed.owl	RNA polymerase III hybrid type promoter DNA binding							krc	2010-08-23T06:21:24Z			GO:0001037		molecular_function											owl:Class	
GO:0000992	biolink:NamedThing	RNA polymerase III cis-regulatory region sequence-specific DNA binding	Binding to a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site) located in cis relative to the transcription start site (i.e., on the same strand of DNA) of a gene transcribed by RNA polymerase III. The transcribed region might be contain a single gene or a cistron containing multiple genes.	tmpzr1t_l9r_go_relaxed.owl								krc	2010-08-11T03:49:28Z					molecular_function											owl:Class	
GO:0002300	biolink:NamedThing	CD8-positive, alpha-beta intraepithelial T cell differentiation	The process in which a precursor cell type acquires the specialized features of a CD8-positive, alpha-beta intraepithelial T cell. Intraepithelial T cells are found among epithelial cells in mucosal areas and have distinct phenotypes and developmental pathways.	tmpzr1t_l9r_go_relaxed.owl	CD8-positive, alpha-beta intraepithelial T-cell differentiation|CD8-positive, alpha-beta intraepithelial T cell development|CD8-positive, alpha-beta intraepithelial T-lymphocyte differentiation|CD8-positive, alpha-beta intraepithelial T lymphocyte differentiation					Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.								biological_process											owl:Class	
GO:0005585	biolink:NamedThing	collagen type II trimer	A collagen homotrimer of alpha1(II) chains; type II collagen triple helices associate to form fibrils.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Collagen_type_II									cellular_component											owl:Class	
GO:0097650	biolink:NamedThing	B axonemal microtubule	An incomplete microtubule containing 10 protofilaments that fuses with a complete microtubule called A tubule (containing 13 protofilaments) to form an axonemal outer doublet.	tmpzr1t_l9r_go_relaxed.owl	B tubule							pr	2014-09-10T20:43:18Z					cellular_component											owl:Class	
GO:0007479	biolink:NamedThing	leg disc proximal/distal pattern formation	The establishment, maintenance and elaboration of the proximal/distal axis of the leg imaginal disc, a precursor to the adult leg.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0048480	biolink:NamedThing	stigma development	The process whose specific outcome is the progression of the stigma over time, from its formation to the mature structure. The stigma is the pollen-receptive surface of a carpel or group of fused carpels, usually sticky.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1900752	biolink:NamedThing	malonic acid transport	The directed movement of a malonic acid into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	HOOC-CH2-COOH transport|propanedioic acid transport|C3H4O4 transport|H2malo transport							jl	2012-05-29T02:40:33Z					biological_process											owl:Class	
GO:0018910	biolink:NamedThing	benzene metabolic process	The chemical reactions and pathways involving benzene, C6H6, a volatile, very inflammable liquid, contained in the naphtha produced by the destructive distillation of coal, from which it is separated by fractional distillation.	tmpzr1t_l9r_go_relaxed.owl	benzene metabolism													biological_process											owl:Class	
GO:0031024	biolink:NamedThing	interphase microtubule organizing center assembly	The aggregation, arrangement and bonding together of a set of components, including gamma-tubulin and other proteins, to form an interphase microtubule organizing center.	tmpzr1t_l9r_go_relaxed.owl	interphase microtubule organising center biosynthesis|interphase microtubule organizing centre assembly|interphase microtubule organizing center biogenesis|interphase microtubule organising center formation													biological_process											owl:Class	
GO:0070291	biolink:NamedThing	N-acylethanolamine metabolic process	The chemical reactions and pathways involving N-acylethanolamines. An N-acylethanolamine is an ethanolamine substituted at nitrogen by an acyl group.	tmpzr1t_l9r_go_relaxed.owl	NAE metabolic process|N-acylethanolamine metabolism|NAE metabolism													biological_process											owl:Class	
GO:0006363	biolink:NamedThing	termination of RNA polymerase I transcription	The process in which the synthesis of an RNA molecule by RNA polymerase I using a DNA template is completed. RNAP I termination requires binding of a terminator protein so specific sequences downstream of the transcription unit.	tmpzr1t_l9r_go_relaxed.owl	transcription termination from RNA polymerase I promoter|termination of RNA polymerase I transcription from promoter for nuclear large rRNA transcript|transcription termination from Pol I promoter|RNA polymerase I transcription termination factor activity|RNA polymerase I transcription termination							krc	2011-08-15T04:07:43Z			GO:0001185|GO:0019223		biological_process											owl:Class	
GO:2000715	biolink:NamedThing	regulation of maintenance of mitotic sister chromatid cohesion, arms	Any process that modulates the frequency, rate or extent of maintenance of mitotic sister chromatid cohesion along the chromosome arms.	tmpzr1t_l9r_go_relaxed.owl	regulation of maintenance of mitotic sister chromatin cohesion along arms|regulation of maintenance of sister chromatin cohesion along arms at mitosis							mah	2011-06-03T10:38:29Z					biological_process											owl:Class	
GO:0065010	biolink:NamedThing	extracellular membrane-bounded organelle	Organized structure of distinctive morphology and function, bounded by a lipid bilayer membrane and occurring outside the cell.	tmpzr1t_l9r_go_relaxed.owl	extracellular membrane-enclosed organelle													cellular_component											owl:Class	
GO:0071382	biolink:NamedThing	cellular response to prostaglandin I stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin I stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-12-11T03:45:10Z					biological_process											owl:Class	
GO:0010174	biolink:NamedThing	nucleoside transmembrane transporter activity, against a concentration gradient	Enables the transfer of a nucleoside, from one side of a membrane to the other, up a concentration gradient.	tmpzr1t_l9r_go_relaxed.owl	concentrative nucleoside transporter activity													molecular_function											owl:Class	
GO:0033473	biolink:NamedThing	indoleacetic acid conjugate metabolic process	The chemical reactions and pathways involving any indole-3-acetic acid conjugate, a form of indoleacetic acid covalently bound to another molecule.	tmpzr1t_l9r_go_relaxed.owl	indoleacetic acid conjugate metabolism|indole acetic acid conjugate metabolic process|indole acetic acid conjugate metabolism|IAA conjugate metabolic process													biological_process											owl:Class	
GO:0097429	biolink:NamedThing	amino acid ligation activity by nonribosomal peptide synthase	Catalysis of the ligation of an amino acid to another amino acid via a carbon-nitrogen bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate, carried out by a nonribosomal peptide synthase.	tmpzr1t_l9r_go_relaxed.owl								pr	2012-11-16T12:34:22Z					molecular_function											owl:Class	
GO:0032789	biolink:NamedThing	unsaturated monocarboxylic acid metabolic process	The chemical reactions and pathways involving unsaturated monocarboxylic acids, any organic acid containing one carboxyl (COOH) group or anion (COO-) and one or more unsaturated C-C bonds.	tmpzr1t_l9r_go_relaxed.owl	unsaturated monocarboxylic acid metabolism|unsaturated monocarboxylate metabolic process													biological_process											owl:Class	
GO:0046586	biolink:NamedThing	regulation of calcium-dependent cell-cell adhesion	Any process that modulates the frequency, rate or extent of the attachment of one cell to another cell via adhesion molecules that require the presence of calcium for the interaction.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1904302	biolink:NamedThing	negative regulation of maternal process involved in parturition	Any process that stops, prevents or reduces the frequency, rate or extent of maternal process involved in parturition.	tmpzr1t_l9r_go_relaxed.owl	downregulation of maternal process involved in parturition|down regulation of maternal process involved in parturition|inhibition of maternal process involved in parturition|down-regulation of maternal process involved in parturition							sl	2015-06-09T23:01:38Z					biological_process											owl:Class	
GO:0019798	biolink:NamedThing	procollagen-proline dioxygenase activity	Catalysis of the reaction: procollagen L-proline + 2-oxoglutarate + O2 = procollagen trans-hydroxy-L-proline + succinate + CO2.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0075259	biolink:NamedThing	spore-bearing structure development	The process whose specific outcome is the progression of a spore-bearing structure over time, from its formation to the mature structure. A spore-bearing structure is an anatomical structure that produces new spores.	tmpzr1t_l9r_go_relaxed.owl	fruiting structure development|spore-bearing organ development|sporangium development|sporophore development													biological_process											owl:Class	
GO:0046839	biolink:NamedThing	phospholipid dephosphorylation	The process of removing one or more phosphate groups from a phosphorylated lipid, any member of a group of substances soluble in lipid solvents but only sparingly soluble in aqueous solvents.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1902317	biolink:NamedThing	nuclear DNA replication termination	Any DNA replication termination that is involved in nuclear cell cycle DNA replication.	tmpzr1t_l9r_go_relaxed.owl	DNA replication termination involved in DNA replication involved in S-phase|DNA replication termination involved in DNA replication involved in S phase|DNA replication termination involved in nuclear cell cycle DNA replication|DNA replication termination involved in DNA replication during S phase							jl	2013-07-23T14:00:17Z					biological_process											owl:Class	
GO:0031446	biolink:NamedThing	regulation of fast-twitch skeletal muscle fiber contraction	Any process that modulates the frequency, rate or extent of fast-twitch skeletal muscle contraction.	tmpzr1t_l9r_go_relaxed.owl	regulation of fast-twitch skeletal muscle contraction													biological_process											owl:Class	
GO:0010691	biolink:NamedThing	negative regulation of ribosomal protein gene transcription from RNA polymerase II promoter in response to nutrient levels	Any process that decreases the frequency, rate or extent of the synthesis of RNA from ribosomal protein genes by RNA polymerase II, originating at an RNA polymerase II promoter, as a result of a stimulus reflecting the presence, absence, or concentration of nutrients.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0010688	biolink:NamedThing	negative regulation of ribosomal protein gene transcription by RNA polymerase II	Any process that decreases the frequency, rate or extent of the synthesis of RNA from ribosomal protein genes mediated by RNA polymerase II.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of ribosomal protein gene transcription from RNA polymerase II promoter													biological_process											owl:Class	
GO:1902807	biolink:NamedThing	negative regulation of cell cycle G1/S phase transition	Any signalling pathway that decreases or inhibits the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G1 phase to S phase of the cell cycle.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of cell cycle G1/S phase transition|inhibition of cell cycle G1/S phase transition|down regulation of cell cycle G1/S phase transition|downregulation of cell cycle G1/S phase transition							jl	2014-03-26T16:36:20Z					biological_process											owl:Class	
GO:0022032	biolink:NamedThing	telencephalon oligodendrocyte cell migration	The multiplication or reproduction of telencephalon oligodendrocyte cells, resulting in the expansion of a cell population.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0061361	biolink:NamedThing	positive regulation of maintenance of bipolar cell polarity regulating cell shape	Any process that increases the frequency, rate or extent of maintenance of bipolar cell polarity regulating cell shape.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-10-13T09:00:59Z					biological_process											owl:Class	
GO:0048769	biolink:NamedThing	sarcomerogenesis	The process in which sarcomeres are added in series within a fiber.	tmpzr1t_l9r_go_relaxed.owl	myofibril production													biological_process											owl:Class	
GO:0060423	biolink:NamedThing	foregut regionalization	The pattern specification process that results in the spatial subdivision of an axis or axes along the foregut to define an area or volume in which specific patterns of cell differentiation will take place.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0004000	biolink:NamedThing	adenosine deaminase activity	Catalysis of the reaction: adenosine + H2O = inosine + NH3.	tmpzr1t_l9r_go_relaxed.owl	adenosine aminohydrolase activity|adenosine deaminase reaction				Reactome:R-HSA-2161195|MetaCyc:ADENODEAMIN-RXN|RHEA:24408|Reactome:R-HSA-74241|Reactome:R-HSA-2161187|Reactome:R-HSA-5693346|EC:3.5.4.4									molecular_function											owl:Class	
GO:0010341	biolink:NamedThing	gibberellin carboxyl-O-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + a gibberellin = S-adenosyl-L-homocysteine + a gibberellin methyl ester.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0047743	biolink:NamedThing	chlordecone reductase activity	Catalysis of the reaction: chlordecone alcohol + NADP(+) = chlordecone + H(+) + NADPH.	tmpzr1t_l9r_go_relaxed.owl	CDR activity|chlordecone-alcohol:NADP+ 2-oxidoreductase activity				RHEA:14401|EC:1.1.1.225|MetaCyc:CHLORDECONE-REDUCTASE-RXN|KEGG_REACTION:R03716									molecular_function											owl:Class	
GO:0051784	biolink:NamedThing	negative regulation of nuclear division	Any process that stops, prevents, or reduces the frequency, rate or extent of nuclear division, the partitioning of the nucleus and its genetic information.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of nuclear division|down regulation of nuclear division|inhibition of nuclear division|downregulation of nuclear division													biological_process											owl:Class	
GO:0031853	biolink:NamedThing	nociceptin receptor binding	Binding to a nociceptin receptor.	tmpzr1t_l9r_go_relaxed.owl	nociceptin receptor ligand													molecular_function											owl:Class	
GO:0071747	biolink:NamedThing	IgA B cell receptor complex	An IgA immunoglobulin complex that is present in the plasma membrane of B cells and is composed of two identical immunoglobulin heavy chains of an IgA isotype and two identical immunoglobulin light chains and a signaling subunit, a heterodimer of the Ig-alpha and Ig-beta proteins.	tmpzr1t_l9r_go_relaxed.owl	surface IgA2|surface IgA|membrane-bound IgA1|surface IgA1|membrane-bound IgA|membrane-bound IgA2					Note that an IgA immunoglobulin complex has the function of antigen binding if a suitable antigen is available.		mah	2010-03-24T01:44:53Z					cellular_component											owl:Class	
GO:0001400	biolink:NamedThing	mating projection base	The region where the mating projection meets the bulk of the cell, in unicellular fungi exposed to mating pheromone.	tmpzr1t_l9r_go_relaxed.owl	conjugation tube base|base of shmoo tip													cellular_component											owl:Class	
GO:0043939	biolink:NamedThing	negative regulation of sporulation	Any process that stops, prevents, or reduces the frequency, rate or extent of sporulation, the process whose specific outcome is the progression of a spore over time, from its initiation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0045642	biolink:NamedThing	positive regulation of basophil differentiation	Any process that activates or increases the frequency, rate or extent of basophil differentiation.	tmpzr1t_l9r_go_relaxed.owl	activation of basophil differentiation|up-regulation of basophil differentiation|upregulation of basophil differentiation|up regulation of basophil differentiation|stimulation of basophil differentiation													biological_process											owl:Class	
GO:0043544	biolink:NamedThing	lipoamide binding	Binding to lipoamide, the functional form of lipoic acid in which the carboxyl group is attached to protein by an amide linkage to a lysine amino group.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0043441	biolink:NamedThing	acetoacetic acid biosynthetic process	The chemical reactions and pathways resulting in the formation of acetoacetic acid, a beta-keto acid of the keto acid group, empirical formula is C4H6O3 or CH3COCH2COOH.	tmpzr1t_l9r_go_relaxed.owl	acetoacetic acid anabolism|acetoacetic acid synthesis|acetoacetic acid biosynthesis|acetoacetic acid formation													biological_process											owl:Class	
GO:0051790	biolink:NamedThing	short-chain fatty acid biosynthetic process	The chemical reactions and pathways resulting in the formation of fatty acids with a chain length of less than C6.	tmpzr1t_l9r_go_relaxed.owl	short chain fatty acid biosynthetic process|short-chain fatty acid anabolism|short-chain fatty acid formation|short-chain fatty acid synthesis|short-chain fatty acid biosynthesis|short chain fatty acid biosynthesis													biological_process											owl:Class	
GO:0019372	biolink:NamedThing	lipoxygenase pathway	The chemical reactions and pathways by which an unsaturated fatty acid (such as arachidonic acid or linolenic acid) is converted to other compounds, and in which the first step is hydroperoxide formation catalyzed by lipoxygenase.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:2000065	biolink:NamedThing	negative regulation of cortisol biosynthetic process	Any process that stops, prevents, or reduces the frequency, rate or extent of cortisol biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of cortisol formation|negative regulation of cortisol biosynthesis|negative regulation of cortisol synthesis|negative regulation of cortisol anabolism							jl	2010-08-20T01:51:23Z					biological_process											owl:Class	
GO:0098745	biolink:NamedThing	Dcp1-Dcp2 complex	A protein complex consisting of a Dcp1 regulatory subunit and a Dcp2 catalytic subunit that has mRNA cap binding activity and is involved in decapping of nuclear-transcribed mRNA.	tmpzr1t_l9r_go_relaxed.owl						Additional components may be present, for example in ascomycetes this complex includes an additional regulatory subunit, Edc1.								cellular_component											owl:Class	
GO:0045434	biolink:NamedThing	negative regulation of female receptivity, post-mating	Any process that stops, prevents or reduces the receptiveness of a female to male advances subsequent to mating.	tmpzr1t_l9r_go_relaxed.owl	inhibition of female receptivity, post-mating|down-regulation of female receptivity, post-mating|downregulation of female receptivity, post-mating|down regulation of female receptivity, post-mating													biological_process											owl:Class	
GO:0007621	biolink:NamedThing	negative regulation of female receptivity	Any process that stops, prevents or reduces the receptiveness of a female to male advances.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of female receptivity|inhibition of female receptivity|down regulation of female receptivity|downregulation of female receptivity													biological_process											owl:Class	
GO:0061721	biolink:NamedThing	6-sulfoquinovose(1-) catabolic process to 3-sulfopropanediol(1-)	The chemical reactions and pathways resulting in the breakdown of 6-sulfoquinovose(1-) resulting in the formation of glycerone phosphate (DHAP) and 3-sulfopropanediol(1-).	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:PWY-7446			dph	2015-07-01T09:20:08Z					biological_process											owl:Class	
GO:0001095	biolink:NamedThing	TFIIE-class transcription factor complex binding	Binding to a general RNA polymerase II transcription factor belonging to the TFIIE complex, one of the factors involved in formation of the preinitiation complex (PIC) by RNA polymerase II.	tmpzr1t_l9r_go_relaxed.owl	TFIIE-class transcription factor binding							krc	2010-10-28T02:49:20Z					molecular_function											owl:Class	
GO:0099083	biolink:NamedThing	retrograde trans-synaptic signaling by neuropeptide, modulating synaptic transmission	Modulation of synaptic transmittion by cell-cell signaling across the synaptic cleft from postsynapse to presynapse, mediated by a neuropeptide.	tmpzr1t_l9r_go_relaxed.owl						Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.								biological_process											owl:Class	
GO:0098984	biolink:NamedThing	neuron to neuron synapse	A synapse in which pre and post-synaptic cells are neurons.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:1903947	biolink:NamedThing	positive regulation of ventricular cardiac muscle cell action potential	Any process that activates or increases the frequency, rate or extent of ventricular cardiac muscle cell action potential.	tmpzr1t_l9r_go_relaxed.owl	activation of ventricular cardiac muscle cell action potential|up regulation of ventricular cardiac muscle cell action potential|upregulation of ventricular cardiac muscle cell action potential|up-regulation of ventricular cardiac muscle cell action potential							nc	2015-02-20T14:32:04Z					biological_process											owl:Class	
GO:1902627	biolink:NamedThing	regulation of assembly of large subunit precursor of preribosome	Any process that modulates the frequency, rate or extent of assembly of a large subunit precursor of preribosome.	tmpzr1t_l9r_go_relaxed.owl	regulation of preribosome, large subunit precursor formation|regulation of 66S preribosome formation|regulation of 66S preribosome assembly							tb	2014-01-16T22:11:45Z					biological_process											owl:Class	
GO:0035232	biolink:NamedThing	germ cell attraction	The directed movement of a germ cell from their site of production to the gonad, through the attraction of cells towards their target.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0070218	biolink:NamedThing	sulfide ion homeostasis	Any process involved in the maintenance of an internal steady state of sulfide ions within an organism or cell.	tmpzr1t_l9r_go_relaxed.owl	sulfide production|sulphide generation|sulphide production|sulfide homeostasis|sulphide ion homeostasis|sulphide homeostasis|sulfide generation													biological_process											owl:Class	
GO:0102934	biolink:NamedThing	costunolide synthase activity	Catalysis of the reaction: germacra-1(10),4,11(13)-trien-12-oate + O2 + NADPH + 2 H+ = costunolide + 2 H2O + NADP.	tmpzr1t_l9r_go_relaxed.owl					EC:1.14.14.150|RHEA:28230|MetaCyc:RXN-8971									molecular_function											owl:Class	
GO:0052777	biolink:NamedThing	diacetylchitobiose catabolic process	The chemical reactions and pathways resulting in the breakdown of diacetylchitobiose into simpler products.	tmpzr1t_l9r_go_relaxed.owl	diacetylchitobiose catabolism													biological_process											owl:Class	
GO:0018264	biolink:NamedThing	isopeptide cross-linking via N-(L-isoaspartyl)-glycine	The formation of an isopeptide cross-link between peptidyl-asparagine and peptidyl-glycine to produce N-(L-isoaspartyl)-glycine.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0126									biological_process											owl:Class	
GO:0061104	biolink:NamedThing	adrenal chromaffin cell differentiation	The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of an adrenal chromaffin cell. An adrenal chromaffin cell is a neuroendocrine cell that stores epinephrine secretory vesicles.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-04-29T08:27:53Z					biological_process											owl:Class	
GO:0080043	biolink:NamedThing	quercetin 3-O-glucosyltransferase activity	Catalysis of the transfer of a glucosyl group from UDP-glucose to the 3-hydroxy group of a quercetin molecule.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0035188	biolink:NamedThing	hatching	The emergence of an immature organism from a protective structure.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0062176	biolink:NamedThing	R-loop disassembly	A DNA metabolic process that results in the disassembly of R-loops. R-loops are three-stranded nucleic acid structures consisitng of an RNA:DNA heteroduplex and a looped-out non-template strand. Aberrant formation and persistence of R-loops block transcription elongation and cause DNA damage. Mechanisms that resolve R-loops are essential for genome stability.	tmpzr1t_l9r_go_relaxed.owl								dph	2019-11-19T12:47:04Z					biological_process											owl:Class	
GO:1904337	biolink:NamedThing	positive regulation of ductus arteriosus closure	Any process that activates or increases the frequency, rate or extent of ductus arteriosus closure.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of ductus arteriosus closure|activation of ductus arteriosus closure|upregulation of ductus arteriosus closure|up regulation of ductus arteriosus closure							sl	2015-06-11T17:45:27Z					biological_process											owl:Class	
GO:0045617	biolink:NamedThing	negative regulation of keratinocyte differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of keratinocyte differentiation.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of keratinocyte differentiation|downregulation of keratinocyte differentiation|down regulation of keratinocyte differentiation|inhibition of keratinocyte differentiation													biological_process											owl:Class	
GO:1905605	biolink:NamedThing	positive regulation of blood-brain barrier permeability	Any process that increases blood-brain barrier permeability, the quality of the blood-brain barrier that allows for a controlled passage of substances (e.g. macromolecules, small molecules, ions) into and out of the brain.	tmpzr1t_l9r_go_relaxed.owl	upregulation of BBB permeability|activation of maintenance of permeability of blood-brain barrier|up-regulation of BBB permeability|upregulation of blood/brain barrier permeability|upregulation of blood-brain barrier permeability|positive regulation of BBB permeability|up-regulation of blood/brain barrier permeability|positive regulation of blood/brain barrier permeability|activation of maintenance of permeability of BBB|up-regulation of blood-brain barrier permeability							als	2016-10-26T13:18:32Z					biological_process											owl:Class	
GO:1905603	biolink:NamedThing	regulation of blood-brain barrier permeability	Any process that modulates blood-brain barrier permeability, the quality of the blood-brain barrier that allows for a controlled passage of substances (e.g. macromolecules, small molecules, ions) into and out of the brain.	tmpzr1t_l9r_go_relaxed.owl	regulation of blood/brain barrier permeability|regulation of BBB permeability							als	2016-10-26T13:18:16Z					biological_process											owl:Class	
GO:0055001	biolink:NamedThing	muscle cell development	The process whose specific outcome is the progression of a muscle cell over time, from its formation to the mature structure. Muscle cell development does not include the steps involved in committing an unspecified cell to the muscle cell fate.	tmpzr1t_l9r_go_relaxed.owl	muscle fiber development|myofibre development|myofiber development|muscle fibre development											GO:0048747		biological_process											owl:Class	
GO:2000796	biolink:NamedThing	Notch signaling pathway involved in negative regulation of venous endothelial cell fate commitment	Any Notch signaling pathway that is involved in negative regulation of venous endothelial cell fate commitment.	tmpzr1t_l9r_go_relaxed.owl	N signaling pathway involved in negative regulation of venous endothelial cell fate commitment|Notch-receptor signalling pathway involved in negative regulation of venous endothelial cell fate commitment|Notch-receptor signaling pathway involved in negative regulation of venous endothelial cell fate commitment|Notch receptor signaling pathway involved in negative regulation of venous endothelial cell fate commitment|Notch signalling pathway involved in negative regulation of venous endothelial cell fate commitment|Notch receptor signalling pathway involved in negative regulation of venous endothelial cell fate commitment							bf	2011-06-27T09:07:42Z					biological_process											owl:Class	
GO:0019441	biolink:NamedThing	tryptophan catabolic process to kynurenine	The chemical reactions and pathways resulting in the breakdown of tryptophan into other compounds, including kynurenine.	tmpzr1t_l9r_go_relaxed.owl	tryptophan degradation to kynurenine|tryptophan breakdown to kynurenine				MetaCyc:TRPKYNCAT-PWY									biological_process											owl:Class	
GO:0030760	biolink:NamedThing	pyridine N-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine(1+) + pyridine = N-methylpyridinium + S-adenosyl-L-homocysteine.	tmpzr1t_l9r_go_relaxed.owl	S-adenosyl-L-methionine:pyridine N-methyltransferase activity|pyridine methyltransferase activity				Reactome:R-HSA-175987|EC:2.1.1.87|MetaCyc:PYRIDINE-N-METHYLTRANSFERASE-RXN|KEGG_REACTION:R02862|RHEA:16893									molecular_function											owl:Class	
GO:0002178	biolink:NamedThing	palmitoyltransferase complex	A protein complex with palmitoyltransferase activity.	tmpzr1t_l9r_go_relaxed.owl								hjd	2010-12-03T10:49:17Z					cellular_component											owl:Class	
GO:0035575	biolink:NamedThing	histone H4-methyl-lysine-20 demethylase activity	Catalysis of the removal of the methyl group from a modified lysine residue at position 20 of the histone H4 protein. This is a dioxygenase reaction that is dependent on Fe(II) and 2-oxoglutarate.	tmpzr1t_l9r_go_relaxed.owl	histone H4K20me demethylase activity|histone demethylase activity (H4-K20 specific)	https://github.com/geneontology/go-ontology/issues/21089			Reactome:R-HSA-2172678			bf	2010-08-13T10:51:13Z					molecular_function											owl:Class	
GO:0070786	biolink:NamedThing	positive regulation of growth of unicellular organism as a thread of attached cells	Any process that activates or increases the frequency, rate or extent of the process in which cells remain attached after division and form thread-like filaments that may penetrate into a solid growth medium.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-07-07T02:39:48Z					biological_process											owl:Class	
GO:0010350	biolink:NamedThing	cellular response to magnesium starvation	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of magnesium.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1901861	biolink:NamedThing	regulation of muscle tissue development	Any process that modulates the frequency, rate or extent of muscle tissue development.	tmpzr1t_l9r_go_relaxed.owl								yaf	2013-02-01T10:30:47Z					biological_process											owl:Class	
GO:0019265	biolink:NamedThing	glycine biosynthetic process, by transamination of glyoxylate	The chemical reactions and pathways resulting in the formation of glycine by the transamination of glyoxylate.	tmpzr1t_l9r_go_relaxed.owl	glycine synthesis, by transamination of glyoxylate|glycine formation, by transamination of glyoxylate|glycine anabolism, by transamination of glyoxylate													biological_process											owl:Class	
GO:1900645	biolink:NamedThing	positive regulation of chanoclavine-I biosynthetic process	Any process that activates or increases the frequency, rate or extent of chanoclavine-I biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of chanoclavine-I anabolism|up-regulation of chanoclavine-I anabolism|up-regulation of chanoclavine-I synthesis|up-regulation of chanoclavine-I biosynthetic process|up regulation of chanoclavine-I biosynthesis|positive regulation of chanoclavine-I biosynthesis|upregulation of chanoclavine-I synthesis|up regulation of chanoclavine-I synthesis|activation of chanoclavine-I formation|upregulation of chanoclavine-I biosynthesis|up regulation of chanoclavine-I biosynthetic process|upregulation of chanoclavine-I biosynthetic process|activation of chanoclavine-I biosynthesis|up-regulation of chanoclavine-I formation|positive regulation of chanoclavine-I formation|activation of chanoclavine-I synthesis|activation of chanoclavine-I anabolism|positive regulation of chanoclavine-I synthesis|up regulation of chanoclavine-I anabolism|up-regulation of chanoclavine-I biosynthesis|activation of chanoclavine-I biosynthetic process|up regulation of chanoclavine-I formation|upregulation of chanoclavine-I anabolism|upregulation of chanoclavine-I formation							di	2012-05-22T04:03:38Z					biological_process											owl:Class	
GO:0071488	biolink:NamedThing	cellular response to very low light intensity stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a very low light intensity stimulus. A very low light intensity stimulus is defined as a level of electromagnetic radiation below 0.001 mmol/m2/sec.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-12-18T02:13:40Z					biological_process											owl:Class	
GO:0071484	biolink:NamedThing	cellular response to light intensity	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light intensity stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-12-18T02:11:03Z					biological_process											owl:Class	
GO:1905141	biolink:NamedThing	negative regulation of apical ectodermal ridge formation	Any process that stops, prevents or reduces the frequency, rate or extent of apical ectodermal ridge formation.	tmpzr1t_l9r_go_relaxed.owl	inhibition of AER formation|downregulation of apical ectodermal ridge formation|inhibition of crista ectodermalis apicalis formation|negative regulation of AER formation|inhibition of apical epidermal ridge formation|down regulation of apical epidermal ridge formation|down-regulation of crista ectodermalis apicalis formation|downregulation of crista ectodermalis apicalis formation|down-regulation of apical epidermal ridge formation|negative regulation of apical epidermal ridge formation|down regulation of apical ectodermal ridge formation|downregulation of apical epidermal ridge formation|down-regulation of AER formation|downregulation of AER formation|down-regulation of apical ectodermal ridge formation|inhibition of apical ectodermal ridge formation|down regulation of AER formation|down regulation of crista ectodermalis apicalis formation|negative regulation of crista ectodermalis apicalis formation							dph	2016-04-13T12:16:48Z					biological_process											owl:Class	
GO:0140245	biolink:NamedThing	regulation of translation at postsynapse	Any process that regulates translation occurring at the postsynapse.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/synapse/issues/210				Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.		pg	2018-07-15T09:38:54Z					biological_process											owl:Class	
GO:0072705	biolink:NamedThing	cellular response to mercaptoethanol	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mercaptoethanol stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to 2-sulfanylethanol							mah	2012-04-11T03:27:40Z					biological_process											owl:Class	
GO:0098855	biolink:NamedThing	HCN channel complex	A cation ion channel with a preference for K+ over Na+ ions, which is activated by membrane hyperpolarization, and consists of a tetramer of HCN family members. Some members of this family (HCN1, HCN2 and HCN4) are also activated when cAMP binds to their cyclic nucleotide binding domain (CNBD). Channel complexes of this family play an important role in the control of pacemaker activity in the heart.	tmpzr1t_l9r_go_relaxed.owl	potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 tetramer|K/Na hyperpolarization-activated cyclic nucleotide-gated channel 1 complex|potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel complex|potassium/sodium hyperpolarization-activated channel 3 complex|potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 tetramer|potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 complex|HCN1 channel complex|potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 complex|potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 complex|K/Na hyperpolarization-activated cyclic nucleotide-gated channel 4 complex|K/Na hyperpolarization-activated cyclic nucleotide-gated channel complex|HCN3 channel complex|HCN2 channel complex|K/Na hyperpolarization-activated channel 3 complex|HCN4 channel complex|K/Na hyperpolarization-activated cyclic nucleotide-gated channel 2 complex											GO:1990746|GO:1990759		cellular_component											owl:Class	
GO:0030510	biolink:NamedThing	regulation of BMP signaling pathway	Any process that modulates the frequency, rate or extent of the activity of any BMP receptor signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	regulation of decapentaplegic receptor signaling pathway|regulation of decapentaplegic signaling pathway|regulation of bone morphogenetic protein signalling pathway|regulation of decapentaplegic receptor signalling pathway|regulation of BMP receptor signaling pathway|regulation of bone morphogenetic protein signaling pathway|regulation of BMP signalling pathway							tb	2009-11-13T10:49:14Z			GO:0090097		biological_process											owl:Class	
GO:0035845	biolink:NamedThing	photoreceptor cell outer segment organization	A process that is carried out at the cellular level and results in the assembly, arrangement of constituent parts, or disassembly of the outer segment of a photoreceptor cell, a sensory cell that reacts to the presence of light. The outer segment of the photoreceptor cell contains the light-absorbing materials.	tmpzr1t_l9r_go_relaxed.owl	photoreceptor outer segment organization|photoreceptor cell outer segment organisation							bf	2011-05-10T10:44:09Z					biological_process											owl:Class	
GO:0021595	biolink:NamedThing	rhombomere structural organization	The process that contributes to the act of creating the structural organization of the rhombomere structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates.	tmpzr1t_l9r_go_relaxed.owl	rhombomere structural organisation													biological_process											owl:Class	
GO:0072680	biolink:NamedThing	extracellular matrix-dependent thymocyte migration	The movement of a thymocyte through distinct intrathymic niches (e.g. medulla, cortex), where it receives a unique set of developmental cues required for T-cell development, dependent on extracellular matrix components including fibronectin, collagen and laminin.	tmpzr1t_l9r_go_relaxed.owl	extracellular matrix-dependent immature T-lymphocyte migration|extracellular matrix-dependent immature T-cell migration|extracellular matrix-dependent thymic lymphocyte migration|extracellular matrix-dependent immature T cell migration|extracellular matrix-dependent immature T lymphocyte migration							mah	2011-02-22T03:49:57Z					biological_process											owl:Class	
GO:0018689	biolink:NamedThing	naphthalene disulfonate 1,2-dioxygenase activity	Catalysis of the reaction: (1/2)-unsubstituted naphthalenoid-(2/1)-sulfonate + 2 H+ + 2 e- + O2 = 1,2-dihydroxynaphthalene derivative + HSO3(-). Substrates include naphthalene-1,6-disulfonate (forms 1,2-dihydroxynaphthalene-6-sulfonate), naphthalene-1-sulfonate (forms 1,2-dihydroxynaphthalene), naphthalene-2,6-disulfonate (forms 1,2-dihydroxynaphthalene-6-sulfonate) and naphthalene-2-sulfonate (forms 1,2-dihydroxynaphthalene).	tmpzr1t_l9r_go_relaxed.owl	naphthalene disulphonate 1,2-dioxygenase activity				UM-BBD_enzymeID:e0249									molecular_function											owl:Class	
GO:0042124	biolink:NamedThing	1,3-beta-glucanosyltransferase activity	Catalysis of the splitting and linkage of (1->3)-beta-D-glucan molecules, resulting in (1->3)-beta-D-glucan chain elongation.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0042123	biolink:NamedThing	glucanosyltransferase activity	Catalysis of the splitting and linkage of glucan molecules, resulting in glucan chain elongation.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0034625	biolink:NamedThing	fatty acid elongation, monounsaturated fatty acid	Elongation of a fatty acid chain into which one C-C double bond has been introduced.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0019368	biolink:NamedThing	fatty acid elongation, unsaturated fatty acid	Elongation of a fatty acid chain into which one or more C-C double bonds have been introduced.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:PWY0-862									biological_process											owl:Class	
GO:0070475	biolink:NamedThing	rRNA base methylation	The addition of a methyl group to an atom in the nucleoside base portion of a nucleotide residue in an rRNA molecule.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0002843	biolink:NamedThing	regulation of tolerance induction to tumor cell	Any process that modulates the frequency, rate, or extent of tolerance induction to tumor cell.	tmpzr1t_l9r_go_relaxed.owl	regulation of tolerance induction to tumour cell													biological_process											owl:Class	
GO:1905005	biolink:NamedThing	regulation of epithelial to mesenchymal transition involved in endocardial cushion formation	Any process that modulates the frequency, rate or extent of epithelial to mesenchymal transition involved in endocardial cushion formation.	tmpzr1t_l9r_go_relaxed.owl								rl	2016-03-01T15:38:39Z					biological_process											owl:Class	
GO:0035716	biolink:NamedThing	chemokine (C-C motif) ligand 12 binding	Binding to chemokine (C-C motif) ligand 12.	tmpzr1t_l9r_go_relaxed.owl	CCL12 binding							bf	2011-03-03T04:25:01Z					molecular_function											owl:Class	
GO:0090496	biolink:NamedThing	mesenchyme migration involved in limb bud formation	The migration of mesenchymal tissue that contributes to the formation of a limb bud.	tmpzr1t_l9r_go_relaxed.owl								tb	2012-10-17T12:04:20Z					biological_process											owl:Class	
GO:0090131	biolink:NamedThing	mesenchyme migration	The process in which the population of cells that make up a mesenchyme undergo directed movement.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-12-07T03:15:17Z					biological_process											owl:Class	
GO:0009723	biolink:NamedThing	response to ethylene	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ethylene (ethene) stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to ethene stimulus|response to ethylene stimulus													biological_process											owl:Class	
GO:1902673	biolink:NamedThing	left posteriolateral basal body	Any ciliary basal body that is part of a left posteriolateral flagellum found in Giardia species (trophozoite stage).	tmpzr1t_l9r_go_relaxed.owl	cilial basal body of left posteriolateral cilium|microtubule basal body of left posteriolateral cilium|left posteriolateral flagellum ciliary basal body|cilial basal body of left posteriolateral flagellum|ciliary basal body of left posterolateral cilium|cilium basal body of left posteriolateral cilium|cilium basal body of left posterolateral cilium|microtubule basal body of left posterolateral cilium|ciliary basal body of left posteriolateral cilium|microtubule basal body of left posteriolateral flagellum|cilial basal body of left posterolateral flagellum|cilial basal body of left posterolateral cilium|microtubule basal body of left posterolateral flagellum|ciliary basal body of left posterolateral flagellum|cilium basal body of left posterolateral flagellum|ciliary basal body of left posteriolateral flagellum|cilium basal body of left posteriolateral flagellum					Note that we deem cilium and microtubule-based flagellum to be equivalent. Also note that, due to the asymmetric nature of the Giardia trophozoite, this term is defined spatially as the trophozoite is viewed from the dorsal side, with the two nuclei dorsal to the ventral disc, and the ventral disc toward the anterior.		pr	2014-02-05T14:49:25Z					cellular_component											owl:Class	
GO:0043698	biolink:NamedThing	iridosome	A tissue-specific, membrane-bounded cytoplasmic organelle within which purines crystalize in reflective stacks. Iridosomes are synthesized in iridophore cells and are silver, gold or iridescent in appearance.	tmpzr1t_l9r_go_relaxed.owl	reflecting platelet													cellular_component											owl:Class	
GO:1900969	biolink:NamedThing	negative regulation of sarcinapterin metabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of sarcinapterin metabolic process.	tmpzr1t_l9r_go_relaxed.owl	down regulation of sarcinapterin metabolism|down-regulation of sarcinapterin metabolic process|downregulation of sarcinapterin metabolic process|downregulation of sarcinapterin metabolism|down-regulation of sarcinapterin metabolism|inhibition of sarcinapterin metabolism|negative regulation of sarcinapterin metabolism|inhibition of sarcinapterin metabolic process|down regulation of sarcinapterin metabolic process							tt	2012-06-14T03:58:35Z					biological_process											owl:Class	
GO:0035915	biolink:NamedThing	pore formation in membrane of other organism	The aggregation, arrangement and bonding together of a set of components by an organism to form a pore complex in a membrane of another organism.	tmpzr1t_l9r_go_relaxed.owl	pore complex assembly in other organism|pore biosynthesis in other organism|pore-forming toxin activity|pore complex biogenesis in other organism|pore formation in other organism							bf	2011-07-01T11:45:01Z					biological_process											owl:Class	
GO:0051673	biolink:NamedThing	membrane disruption in other organism	The disruption of the membranes of another organism, leading to damage to its cells and possibly death of that organism.	tmpzr1t_l9r_go_relaxed.owl	membrane disruption in another organism|cytolysis, by membrane disruption, in other organism													biological_process											owl:Class	
GO:2000532	biolink:NamedThing	regulation of renal albumin absorption	Any process that modulates the frequency, rate or extent of renal albumin absorption.	tmpzr1t_l9r_go_relaxed.owl								pr	2011-03-24T03:28:06Z					biological_process											owl:Class	
GO:0008868	biolink:NamedThing	galactitol-1-phosphate 5-dehydrogenase activity	Catalysis of the reaction: galactitol-1-phosphate + NAD+ = D-tagatose 6-phosphate + NADH + H+.	tmpzr1t_l9r_go_relaxed.owl	galactitol-1-phosphate:NAD+ oxidoreductase activity				MetaCyc:1.1.1.251-RXN|EC:1.1.1.251|RHEA:15137									molecular_function											owl:Class	
GO:0034898	biolink:NamedThing	hexadecyltrimethylammonium chloride monooxygenase activity	Catalysis of the reaction: hexadecyltrimethylammonium chloride + NAD(P)H + H+ + O2 = trimethylamine + hexadecanal + NAD(P)+ + H2O.	tmpzr1t_l9r_go_relaxed.owl					EC:1.13.12.-|UM-BBD_reactionID:r1373									molecular_function											owl:Class	
GO:0002142	biolink:NamedThing	stereocilia ankle link complex	A complex of proteins that connect growing stereocilia in developing cochlear hair cells, composed of Vlgr1, usherin, vezatin, and whirlin.	tmpzr1t_l9r_go_relaxed.owl								hjd	2009-05-06T10:33:57Z					cellular_component											owl:Class	
GO:0090025	biolink:NamedThing	regulation of monocyte chemotaxis	Any process that modulates the frequency, rate, or extent of monocyte chemotaxis.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-08-03T10:17:03Z					biological_process											owl:Class	
GO:0005704	biolink:NamedThing	polytene chromosome band	A stretch of densely packed chromatin along the polytene chromosome, visible as a morphologically distinct band.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0072701	biolink:NamedThing	cellular response to bismuth	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bismuth (Bi) stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to bismuth ion							mah	2012-04-11T02:56:42Z					biological_process											owl:Class	
GO:0072700	biolink:NamedThing	response to bismuth	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bismuth (Bi) stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to bismuth ion							mah	2012-04-11T02:56:35Z					biological_process											owl:Class	
GO:0019431	biolink:NamedThing	acetyl-CoA biosynthetic process from ethanol	The chemical reactions and pathways resulting in the formation of acetyl-CoA from ethanol via acetaldehyde.	tmpzr1t_l9r_go_relaxed.owl	acetyl-CoA anabolism from ethanol|acetyl-CoA synthesis from ethanol|acetyl-CoA formation from ethanol				MetaCyc:ETOH-ACETYLCOA-ANA-PWY									biological_process											owl:Class	
GO:0051547	biolink:NamedThing	regulation of keratinocyte migration	Any process that modulates the frequency, rate or extent of keratinocyte migration.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0060444	biolink:NamedThing	branching involved in mammary gland duct morphogenesis	The process in which the branching structure of the mammary gland duct is generated and organized. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk.	tmpzr1t_l9r_go_relaxed.owl	mammary gland branching morphogenesis													biological_process											owl:Class	
GO:1903854	biolink:NamedThing	negative regulation of stress response to copper ion	Any process that stops, prevents or reduces the frequency, rate or extent of stress response to copper ion.	tmpzr1t_l9r_go_relaxed.owl	inhibition of response to copper toxicity|inhibition of response to copper ion stress|down regulation of response to copper toxicity|down-regulation of stress response to copper ion|downregulation of stress response to copper ion|down-regulation of response to copper ion stress|downregulation of response to copper toxicity|down regulation of stress response to copper ion|inhibition of stress response to copper ion|negative regulation of response to copper ion stress|negative regulation of response to copper toxicity|downregulation of response to copper ion stress|down-regulation of response to copper toxicity|down regulation of response to copper ion stress							kmv	2015-01-29T20:15:33Z					biological_process											owl:Class	
GO:0030973	biolink:NamedThing	molybdate ion binding	Binding to a molybdate ion (MoO4 2-).	tmpzr1t_l9r_go_relaxed.owl	MoO4 ion binding													molecular_function											owl:Class	
GO:1903711	biolink:NamedThing	spermidine transmembrane transport	The process in which spermidine is transported across a membrane.	tmpzr1t_l9r_go_relaxed.owl								vw	2014-12-06T08:12:44Z					biological_process											owl:Class	
GO:0047220	biolink:NamedThing	galactosylxylosylprotein 3-beta-galactosyltransferase activity	Catalysis of the reaction: 4-beta-D-galactosyl-O-beta-D-xylosylprotein + UDP-galactose = 3-beta-D-galactosyl-4-beta-D-galactosyl-O-beta-D-xylosylprotein + UDP.	tmpzr1t_l9r_go_relaxed.owl	galactosyltransferase II activity|uridine diphosphogalactose-galactosylxylose galactosyltransferase activity|UDPgalactose:4-beta-D-galactosyl-O-beta-D-xylosylprotein 3-beta-D-galactosyltransferase activity|UDP-galactose:4-beta-D-galactosyl-O-beta-D-xylosylprotein 3-beta-D-galactosyltransferase activity				EC:2.4.1.134|RHEA:11780|MetaCyc:2.4.1.134-RXN|Reactome:R-HSA-4420365|Reactome:R-HSA-1889978									molecular_function											owl:Class	
GO:0007371	biolink:NamedThing	ventral midline determination	The regionalization process in which the area where the ventral midline will form is specified.	tmpzr1t_l9r_go_relaxed.owl	determination of posterior border of ventral midline|determination of anterior border of ventral midline											GO:0007372|GO:0007373		biological_process											owl:Class	
GO:1901782	biolink:NamedThing	p-cumate catabolic process	The chemical reactions and pathways resulting in the breakdown of p-cumate.	tmpzr1t_l9r_go_relaxed.owl	p-cumate breakdown|p-cumate catabolism|p-cumate degradation							yaf	2013-01-16T10:40:32Z					biological_process											owl:Class	
GO:0034303	biolink:NamedThing	myxospore formation	The process in which differentiated, resting cells are formed, usually within a fruiting body by Myxobacteria. The myxospore is more resistant to high temperature, dessication, and UV than vegetative myxobacteria.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0044570	biolink:NamedThing	starch utilization system complex	A bacterial cell envelope-associated multiprotein system, which binds and degrades starch.	tmpzr1t_l9r_go_relaxed.owl	Sus complex							jl	2012-04-18T02:46:24Z					cellular_component											owl:Class	
GO:1901521	biolink:NamedThing	aspyridone B biosynthetic process	The chemical reactions and pathways resulting in the formation of aspyridone B.	tmpzr1t_l9r_go_relaxed.owl	aspyridone B synthesis|aspyridone B biosynthesis|aspyridone B formation|aspyridone B anabolism							di	2012-10-18T18:31:52Z					biological_process											owl:Class	
GO:1901519	biolink:NamedThing	aspyridone B metabolic process	The chemical reactions and pathways involving aspyridone B.	tmpzr1t_l9r_go_relaxed.owl	aspyridone B metabolism							di	2012-10-18T18:31:40Z					biological_process											owl:Class	
GO:0008554	biolink:NamedThing	P-type sodium transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Na+(in) -> ADP + phosphate + Na+(out); by a phosphorylative mechanism.	tmpzr1t_l9r_go_relaxed.owl	sodium-exporting ATPase activity, phosphorylative mechanism|sodium transport ATPase activity|Na(+)-exporting ATPase activity|Na+-transporting ATPase activity|sodium-translocating P-type ATPase activity|Na+-exporting ATPase activity|sodium-exporting ATPase activity|Na(+)-transporting ATPase activity|sodium transmembrane transporter activity, phosphorylative mechanism|sodium exporting ATPase activity, phosphorylative mechanism	https://github.com/geneontology/go-ontology/issues/21796			EC:7.2.2.3|RHEA:14633|MetaCyc:3.6.3.7-RXN	Note that RHEA:14633 represents both the ABC and the P-type sodium transporters.								molecular_function											owl:Class	
GO:0051798	biolink:NamedThing	positive regulation of hair follicle development	Any process that activates or increases the frequency, rate or extent of hair follicle development.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of hair follicle development|up regulation of hair follicle development|stimulation of hair follicle development|activation of hair follicle development|upregulation of hair follicle development													biological_process											owl:Class	
GO:1900722	biolink:NamedThing	regulation of protein adenylylation	Any process that modulates the frequency, rate or extent of protein adenylylation.	tmpzr1t_l9r_go_relaxed.owl	regulation of protein adenylation|regulation of protein amino acid adenylylation|regulation of protein AMPylation							jl	2012-05-24T03:15:44Z					biological_process											owl:Class	
GO:0099634	biolink:NamedThing	postsynaptic specialization membrane	The membrane component of the postsynaptic specialization. This is the region of the postsynaptic membrane in which the population of neurotransmitter receptors involved in synaptic transmission are concentrated.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0015325	biolink:NamedThing	acetyl-CoA:CoA antiporter activity	Catalysis of the reaction: acetyl-CoA(out) + CoA(in) = acetyl-CoA(in) + CoA(out).	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0008521	biolink:NamedThing	acetyl-CoA transmembrane transporter activity	Enables the transfer of acetyl-CoA from one side of a membrane to the other. Acetyl-CoA is a derivative of coenzyme A in which the sulfhydryl group is acetylated; it is a metabolite derived from several pathways (e.g. glycolysis, fatty acid oxidation, amino-acid catabolism) and is further metabolized by the tricarboxylic acid cycle. It is a key intermediate in lipid and terpenoid biosynthesis.	tmpzr1t_l9r_go_relaxed.owl	acetyl-CoA transporter activity				Reactome:R-HSA-727759|Reactome:R-HSA-5649742									molecular_function											owl:Class	
GO:0050631	biolink:NamedThing	corydaline synthase activity	Catalysis of the reaction: S-adenosyl-L-methionine + 2 NADPH + palmatine = S-adenosyl-L-homocysteine + corydaline + 2 NADP(+).	tmpzr1t_l9r_go_relaxed.owl	S-adenosyl-L-methionine:protoberberine 13-C-methyltransferase activity				KEGG_REACTION:R07241|EC:2.1.1.147|MetaCyc:2.1.1.147-RXN|RHEA:14773									molecular_function											owl:Class	
GO:0061129	biolink:NamedThing	negative regulation of positive chemotaxis to cAMP by DIF-2	Any process that decreases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of DIF-2. DIF-2 is a chlorinated alkylphenone.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-05-17T08:50:33Z					biological_process											owl:Class	
GO:0061125	biolink:NamedThing	negative regulation of positive chemotaxis to cAMP by chlorinated alkylphenone	Any process that decreases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of a chlorinated alkylphenone. An alkylphenone is an aromatic polyketide with methyl and chlorine substitutions.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-05-17T08:36:55Z					biological_process											owl:Class	
GO:0047376	biolink:NamedThing	all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity	Catalysis of the reaction: all-trans-retinyl palmitate + H2O = all-trans-retinol + H+ + palmitate.	tmpzr1t_l9r_go_relaxed.owl	retinyl-palmitate palmitohydrolase activity|all-trans-retinyl-palmitate hydrolase activity|all-trans-retinyl-palmitate acylhydrolase activity				MetaCyc:3.1.1.64-RXN|Reactome:R-HSA-2429643|Reactome:R-HSA-2404140|KEGG_REACTION:R02368|RHEA:13933									molecular_function											owl:Class	
GO:0060528	biolink:NamedThing	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development	The process in which a relatively unspecialized epithelial cell acquires specialized features of a secretory columnal luminar epithelial cell of the prostate.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0016336	biolink:NamedThing	establishment or maintenance of polarity of larval imaginal disc epithelium	Any cellular process that results in the specification, formation or maintenance of a polarized larval imaginal disc epithelium.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0035823	biolink:NamedThing	short tract gene conversion	A gene conversion process in which a segment of about 50-200 base pairs is transferred from the donor to the acceptor.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-05-04T01:05:35Z					biological_process											owl:Class	
GO:0048084	biolink:NamedThing	positive regulation of adult chitin-containing cuticle pigmentation	Any process that activates or increases the frequency, rate or extent of establishment of the adult pattern of pigmentation in the cuticle of an organism.	tmpzr1t_l9r_go_relaxed.owl	stimulation of adult chitin-containing cuticle pigmentation|up-regulation of adult chitin-containing cuticle pigmentation|activation of adult chitin-containing cuticle pigmentation|up regulation of adult chitin-containing cuticle pigmentation|upregulation of adult chitin-containing cuticle pigmentation													biological_process											owl:Class	
GO:0048082	biolink:NamedThing	regulation of adult chitin-containing cuticle pigmentation	Any process that modulates the frequency, rate or extent of establishment of the adult pattern of pigmentation in the cuticle of an organism.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0000234	biolink:NamedThing	phosphoethanolamine N-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + ethanolamine phosphate = S-adenosyl-L-homocysteine + N-methylethanolamine phosphate.	tmpzr1t_l9r_go_relaxed.owl	S-adenosyl-L-methionine:ethanolamine-phosphate N-methyltransferase activity|phosphoethanolamine methyltransferase activity				EC:2.1.1.103|KEGG_REACTION:R02037|MetaCyc:2.1.1.103-RXN|RHEA:20365									molecular_function											owl:Class	
GO:0070801	biolink:NamedThing	positive regulation of conidiophore stalk development	Any process that activates or increases the frequency, rate or extent of conidiophore stalk development, a process that leads to the formation of a conidiophore stalk. The conidiophore stalk is part of a specialized hypha that extends aerially from the growth substrate and supports structures from which conidia, or asexual spores, develop.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-07-08T04:11:22Z					biological_process											owl:Class	
GO:1903884	biolink:NamedThing	regulation of chemokine (C-C motif) ligand 20 production	Any process that modulates the frequency, rate or extent of chemokine (C-C motif) ligand 20 production.	tmpzr1t_l9r_go_relaxed.owl	regulation of CCL20 production|regulation of CCL-20 production|regulation of C-C motif chemokine 20 production							krc	2015-02-06T16:31:02Z					biological_process											owl:Class	
GO:0042914	biolink:NamedThing	colicin transport	The directed movement of a colicin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Colicins are a group of antibiotics produced by E. coli and related species that are encoded by a group of naturally occurring plasmids, e.g. Col E1.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0043213	biolink:NamedThing	bacteriocin transport	The directed movement of a bacteriocin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Bacteriocins are a group of antibiotics produced by bacteria and are encoded by a group of naturally occurring plasmids, e.g. Col E1. Bacteriocins are toxic to bacteria closely related to the bacteriocin producing strain.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0008934	biolink:NamedThing	inositol monophosphate 1-phosphatase activity	Catalysis of the reaction: myo-inositol 1-phosphate + H2O = myo-inositol + phosphate.	tmpzr1t_l9r_go_relaxed.owl	L-myo-inositol-1-phosphate phosphatase activity|inositol 1-phosphatase activity|myo-inositol 1-phosphatase activity|myo-inositol-1(or 4)-phosphate phosphohydrolase activity|myo-inositol-1-phosphatase activity|myo-inositol-1(or 4)-monophosphatase activity|inositol-1(or 4)-monophosphatase activity				RHEA:27670|EC:3.1.3.25|Reactome:R-HSA-1855154|MetaCyc:RXN0-5408									molecular_function											owl:Class	
GO:0030697	biolink:NamedThing	S-adenosylmethionine-dependent tRNA (m5U54) methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing thymine at position U54 of a transfer RNA. This occurs in most Gram-negative bacteria, some archae, and eukaryotes.	tmpzr1t_l9r_go_relaxed.owl	transfer RNA uracil 5-methyltransferase activity|ribothymidyl synthase activity|RUMT|M5U-methyltransferase activity|tRNA uracil 5-methyltransferase activity|S-adenosyl-L-methionine:tRNA (uracil-5-)-methyltransferase activity|tRNA (uracil-5-)-methyltransferase activity|S-adenosyl methionine-dependent tRNA (m5U54) methyltransferase activity|transfer RNA uracil methylase activity|tRNA:m5U54-methyltransferase activity|RUMT activity|tRNA:m(5)U54-methyltransferase activity				EC:2.1.1.35|RHEA:42712|MetaCyc:TRNA-URACIL-5--METHYLTRANSFERASE-RXN							GO:0009021		molecular_function											owl:Class	
GO:0000836	biolink:NamedThing	Hrd1p ubiquitin ligase complex	A multiprotein complex that recognizes and ubiquitinates proteins with misfolded luminal and membrane domains during ER-associated protein degradation (ERAD). In S. cerevisiae, this complex contains the ubiquitin ligase Hrd1p. In mammals, this complex contains the ubiquitin ligase HRD1 (Synoviolin) or AMFR (gp78).	tmpzr1t_l9r_go_relaxed.owl	HRD1 ubiquitin ligase complex													cellular_component											owl:Class	
GO:0019530	biolink:NamedThing	taurine metabolic process	The chemical reactions and pathways involving taurine (2-aminoethanesulfonic acid), a sulphur-containing amino acid derivative important in the metabolism of fats.	tmpzr1t_l9r_go_relaxed.owl	taurine metabolism													biological_process											owl:Class	
GO:0009301	biolink:NamedThing	snRNA transcription	The synthesis of small nuclear RNA (snRNA) from a DNA template.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0045338	biolink:NamedThing	farnesyl diphosphate metabolic process	The chemical reactions and pathways involving farnesyl diphosphate, an intermediate in carotenoid, sesquiterpene, squalene and sterol biosynthesis, as well as a substrate in protein farnesylation.	tmpzr1t_l9r_go_relaxed.owl	farnesyl diphosphate metabolism													biological_process											owl:Class	
GO:0044703	biolink:NamedThing	multi-organism reproductive process	A biological process that directly contributes to the process of producing new individuals, involving another organism.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-09-19T15:56:30Z					biological_process											owl:Class	
GO:0060902	biolink:NamedThing	regulation of hair cycle by BMP signaling pathway	A series of molecular signals generated as a consequence of any member of the BMP (bone morphogenetic protein) family binding to a cell surface receptor that modulates the rate, frequency or extent of the hair cycle.	tmpzr1t_l9r_go_relaxed.owl	regulation of hair cycle by BMP signalling pathway							dph	2009-08-13T02:45:12Z					biological_process											owl:Class	
GO:1903174	biolink:NamedThing	fatty alcohol catabolic process	The chemical reactions and pathways resulting in the breakdown of fatty alcohol.	tmpzr1t_l9r_go_relaxed.owl	fatty alcohol degradation|fatty alcohol breakdown|fatty alcohol catabolism							tt	2014-07-14T01:51:48Z					biological_process											owl:Class	
GO:0008690	biolink:NamedThing	3-deoxy-manno-octulosonate cytidylyltransferase activity	Catalysis of the reaction: CTP + 3-deoxy-D-manno-octulosonate = diphosphate + CMP-3-deoxy-D-manno-octulosonate.	tmpzr1t_l9r_go_relaxed.owl	CMP-KDO synthetase activity|cytidine monophospho-3-deoxy-D-manno-octulosonate pyrophosphorylase activity|2-keto-3-deoxyoctonate cytidylyltransferase activity|CMP-3-deoxy-D-manno-octulosonate synthetase activity|CMP-2-keto-3-deoxyoctulosonic acid synthetase activity|CTP:3-deoxy-manno-octulosonate cytidylyltransferase activity|CMP-3-deoxy-D-manno-octulosonate pyrophosphorylase activity|CMP-3-deoxy-D-manno-octulosonate diphosphorylase activity|CTP:CMP-3-deoxy-D-manno-octulosonate cytidylyltransferase activity|3-deoxy-D-manno-octulosonate cytidylyltransferase activity|CTP:3-deoxy-D-manno-octulosonate cytidylyltransferase activity				EC:2.7.7.38|MetaCyc:CPM-KDOSYNTH-RXN|RHEA:23448									molecular_function											owl:Class	
GO:0072751	biolink:NamedThing	cellular response to L-thialysine	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-thialysine stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to thialysine							mah	2012-09-10T14:12:21Z					biological_process											owl:Class	
GO:1903859	biolink:NamedThing	regulation of dendrite extension	Any process that modulates the frequency, rate or extent of dendrite extension.	tmpzr1t_l9r_go_relaxed.owl						An example of this is Mul1 in mouse (UniProt ID Q8VCM5) in PMID:24898855 inferred from mutant phenotype.		pad	2015-02-02T15:33:51Z					biological_process											owl:Class	
GO:0030300	biolink:NamedThing	regulation of intestinal cholesterol absorption	Any process that modulates the frequency, rate or extent of absorption of cholesterol into the blood, and the exclusion of other sterols from absorption.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1904002	biolink:NamedThing	regulation of sebum secreting cell proliferation	Any process that modulates the frequency, rate or extent of sebum secreting cell proliferation.	tmpzr1t_l9r_go_relaxed.owl	regulation of sebocyte proliferation							hjd	2015-03-06T16:19:44Z					biological_process											owl:Class	
GO:0072096	biolink:NamedThing	negative regulation of branch elongation involved in ureteric bud branching	Any process that reduces the frequency, rate or extent of branch elongation involved in ureteric bud branching, the growth of a branch of the ureteric bud along its axis.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-02-10T01:52:09Z					biological_process											owl:Class	
GO:0090111	biolink:NamedThing	regulation of COPII vesicle uncoating	Any process that modulates the frequency, rate or extent of COPII vesicle uncoating, the process in which COPII vesicle coat proteins are disassembled, and released.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-12-06T08:34:01Z					biological_process											owl:Class	
GO:1900093	biolink:NamedThing	positive regulation of raffinose biosynthetic process	Any process that activates or increases the frequency, rate or extent of raffinose biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	activation of raffinose anabolism|positive regulation of raffinose synthesis|up-regulation of raffinose biosynthetic process|up-regulation of raffinose synthesis|up regulation of raffinose anabolism|positive regulation of raffinose formation|up regulation of raffinose synthesis|upregulation of raffinose biosynthesis|upregulation of raffinose anabolism|upregulation of raffinose synthesis|positive regulation of raffinose anabolism|up regulation of raffinose formation|activation of raffinose biosynthetic process|up regulation of raffinose biosynthesis|activation of raffinose formation|positive regulation of raffinose biosynthesis|activation of raffinose synthesis|up-regulation of raffinose anabolism|up regulation of raffinose biosynthetic process|up-regulation of raffinose formation|upregulation of raffinose biosynthetic process|up-regulation of raffinose biosynthesis|activation of raffinose biosynthesis|upregulation of raffinose formation							dhl	2012-02-08T06:32:01Z					biological_process											owl:Class	
GO:0016675	biolink:NamedThing	oxidoreductase activity, acting on a heme group of donors	Catalysis of an oxidation-reduction (redox) reaction in which a heme group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.	tmpzr1t_l9r_go_relaxed.owl	oxidoreductase activity, acting on heme group of donors, other acceptors|oxidoreductase activity, acting on haem group of donors				EC:1.9.-.-									molecular_function											owl:Class	
GO:0090241	biolink:NamedThing	negative regulation of histone H4 acetylation	Any process that decreases the rate, frequency, or extent of histone H4 acetylation, the modification of histone H4 by the addition of an acetyl group.	tmpzr1t_l9r_go_relaxed.owl								tb	2010-01-20T03:48:09Z					biological_process											owl:Class	
GO:0016756	biolink:NamedThing	glutathione gamma-glutamylcysteinyltransferase activity	Catalysis of the reaction: glutathione + Glu(-Cys)(n)-Gly = Gly + Glu(-Cys)(n+1)-Gly.	tmpzr1t_l9r_go_relaxed.owl	glutathione:poly(4-glutamyl-cysteinyl)glycine 4-glutamylcysteinyltransferase activity|phytochelatin synthase activity|gamma-glutamylcysteine dipeptidyl transpeptidase activity				MetaCyc:2.3.2.15-RXN|EC:2.3.2.15|RHEA:17917							GO:0042143		molecular_function											owl:Class	
GO:0001835	biolink:NamedThing	blastocyst hatching	The hatching of the cellular blastocyst from the zona pellucida.	tmpzr1t_l9r_go_relaxed.owl						See also the Anatomical Dictionary for Mouse Development ontology terms 'TS4, zona pellucida ; EMAP:22' and 'TS5, embryo ; EMAP:23'.								biological_process											owl:Class	
GO:0009128	biolink:NamedThing	purine nucleoside monophosphate catabolic process	The chemical reactions and pathways resulting in the breakdown of purine nucleoside monophosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with phosphate on the sugar.	tmpzr1t_l9r_go_relaxed.owl	purine nucleoside monophosphate catabolism|purine nucleoside monophosphate breakdown|purine nucleoside monophosphate degradation													biological_process											owl:Class	
GO:0102173	biolink:NamedThing	24-methylenecycloartanol 4alpha-methyl oxidase activity	Catalysis of the reaction: 24-methylenecycloartanol + NADH + O2 + H+ <=> 4alpha-hydroxymethyl,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(241)-en-3beta-ol + NAD + H2O.	tmpzr1t_l9r_go_relaxed.owl					RHEA:58836|MetaCyc:RXN-11926									molecular_function											owl:Class	
GO:1990660	biolink:NamedThing	calprotectin complex	A protein complex composed of S100A8 and S100A9 and capable of limiting Mn(2+) and Zn(2+) availability at sites of infection. Also binds Ca(2+). Expressed and released by neutrophils and epithelial cells, it exhibits broad-spectrum antimicrobial activity attributed to its metal-binding properties. Endogenous ligand of toll-like receptor 4 (TLR4) and of the receptor for advanced glycation end products (RAGE) initiating signal transduction through NF-kappa-B pathways.	tmpzr1t_l9r_go_relaxed.owl	calprotectin heterodimer					An example of this is S100A9 in human (UniProt symbol P06702) in PMID:25417112 (inferred from direct assay).		bhm	2015-02-25T14:03:17Z					cellular_component											owl:Class	
GO:0006517	biolink:NamedThing	protein deglycosylation	The removal of sugar residues from a glycosylated protein.	tmpzr1t_l9r_go_relaxed.owl	glycoprotein deglycosylation													biological_process											owl:Class	
GO:2000102	biolink:NamedThing	negative regulation of mammary stem cell proliferation	Any process that stops, prevents, or reduces the frequency, rate or extent of mammary stem cell proliferation.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-09-14T06:10:34Z					biological_process											owl:Class	
GO:0060818	biolink:NamedThing	inactivation of paternal X chromosome by genetic imprinting	Compensating for the two-fold variation in X-chromosome:autosome ratios between sexes by a global inactivation of all, or most of, the genes on the paternal X-chromosome in the XX sex by genetic imprinting.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-08-11T10:52:31Z					biological_process											owl:Class	
GO:1990304	biolink:NamedThing	MUB1-RAD6-UBR2 ubiquitin ligase complex	A ubiquitin ligase complex consisting of MUB1, RAD6 and UBR2 components. It ubiquitinates, and targets for destruction, the RPN4 transcription factor, which upregulates the proteasome genes. The binding of MUB1 may position the RPN4 ubiquitylation site proximal to the Ubiquitin-RAD6 thioester and allow the transfer of Ubiquitin from RAD6 to RPN4. One of its components, MUB1, is a short-lived protein ubiquitinated by the UBR2-RAD6 ubiquitin conjugating enzyme.	tmpzr1t_l9r_go_relaxed.owl						This complex has been identified in Saccharomyces cerevisiae (UniProt symbol P19812) - see PMID:18070918.		bhm	2014-03-03T21:54:21Z					cellular_component											owl:Class	
GO:0030965	biolink:NamedThing	plasma membrane electron transport, NADH to quinone	The transfer of electrons from NADH to the quinone pool that occurs during oxidative phosphorylation and results in the generation of a proton gradient, mediated by the enzyme known as NADH-quinone oxidoreductase.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0033614	biolink:NamedThing	chloroplast proton-transporting ATP synthase complex assembly	The aggregation, arrangement and bonding together of a proton-transporting ATP synthase in the chloroplast thylakoid membrane.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:2001039	biolink:NamedThing	negative regulation of cellular response to drug	Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to drug.	tmpzr1t_l9r_go_relaxed.owl								yaf	2011-08-27T04:12:23Z					biological_process											owl:Class	
GO:0009328	biolink:NamedThing	phenylalanine-tRNA ligase complex	An enzyme complex that catalyzes the ligation of phenylalanine to tRNA(Phe), forming L-phenylalanyl-tRNA(Phe).	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0097415	biolink:NamedThing	cortical Lewy body	Cytoplasmic inclusion similar to a classical Lewy body but lacking a halo of protein fibrils.	tmpzr1t_l9r_go_relaxed.owl					NIF_Subcellular:sao4040591221			pr	2012-11-06T16:29:11Z					cellular_component											owl:Class	
GO:0097413	biolink:NamedThing	Lewy body	Cytoplasmic, spherical inclusion commonly found in damaged neurons, and composed of abnormally phosphorylated, neurofilament proteins aggregated with ubiquitin and alpha-synuclein.	tmpzr1t_l9r_go_relaxed.owl	cytoplasmic inclusion				NIF_Subcellular:sao4933778419			pr	2012-11-06T16:26:08Z					cellular_component											owl:Class	
GO:1904432	biolink:NamedThing	regulation of ferrous iron binding	Any process that modulates the frequency, rate or extent of ferrous iron binding.	tmpzr1t_l9r_go_relaxed.owl								kom	2015-07-06T13:46:30Z					biological_process											owl:Class	
GO:0034465	biolink:NamedThing	response to carbon monoxide	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbon monoxide (CO) stimulus.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0000905	biolink:NamedThing	sporocarp development involved in asexual reproduction	The formation of a spore-bearing structure by fungus where spores will arise from asexual reproduction.	tmpzr1t_l9r_go_relaxed.owl	monokaryotic fruiting|homokaryotic fruiting|haploid fruiting|fruiting body formation involved in asexual reproduction|conidium development|imperfect stage fruiting body development													biological_process											owl:Class	
GO:0030584	biolink:NamedThing	sporocarp development	The process whose specific outcome is the progression of a sporocarp over time, from its formation to the mature structure. The sporocarp is a spore bearing fruiting body organ. An example of this process is found in the Fungal species Coprinopsis cinerea.	tmpzr1t_l9r_go_relaxed.owl	fruiting body development													biological_process											owl:Class	
GO:0034657	biolink:NamedThing	GID complex	A protein complex with ubiquitin ligase activity that is involved in proteasomal degradation of fructose-1,6-bisphosphatase (FBPase) and phosphoenolpyruvate carboxykinase during the transition from gluconeogenic to glycolytic growth conditions. In S. cerevisiae, the GID (Glucose Induced degradation Deficient) complex consists of Vid30p, Rmd5p, Vid24p, Vid28p, Gid7p, Gid8p, and Fyv10p.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0035473	biolink:NamedThing	lipase binding	Binding to a lipase.	tmpzr1t_l9r_go_relaxed.owl								bf	2010-04-22T05:28:52Z					molecular_function											owl:Class	
GO:0070039	biolink:NamedThing	rRNA (guanosine-2'-O-)-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing 2'-O-methylguanosine.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-6793096|Reactome:R-HSA-6793122									molecular_function											owl:Class	
GO:0030309	biolink:NamedThing	poly-N-acetyllactosamine metabolic process	The chemical reactions and pathways involving poly-N-acetyllactosamine, a carbohydrate composed of N-acetyllactosamine repeats (Gal-beta-1,4-GlcNAc-beta-1,3)n.	tmpzr1t_l9r_go_relaxed.owl	poly-N-acetyllactosamine metabolism													biological_process											owl:Class	
GO:0002490	biolink:NamedThing	antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-independent	The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class Ib protein complex following intracellular transport via a pathway not requiring TAP (transporter associated with antigen processing). The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E gene family.	tmpzr1t_l9r_go_relaxed.owl	TAP-independent endogenous peptide antigen processing and presentation via MHC class Ib via ER pathway|TAP-independent antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway|endogenous peptide antigen processing and presentation via MHC class Ib via ER pathway, TAP-independent													biological_process											owl:Class	
GO:0002488	biolink:NamedThing	antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway	The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class Ib protein complex following intracellular transport via an ER pathway. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell and becomes associated with the MHC class Ib molecule in the ER. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E gene family.	tmpzr1t_l9r_go_relaxed.owl	endogenous peptide antigen processing and presentation via MHC class Ib via ER pathway													biological_process											owl:Class	
GO:0070954	biolink:NamedThing	negative regulation of neutrophil mediated cytotoxicity	Any process that decreases the frequency, rate or extent of the directed killing of a target cell by a neutrophil.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of neutrophil mediated cell killing|down regulation of neutrophil mediated cytotoxicity|down-regulation of neutrophil mediated cytotoxicity|downregulation of neutrophil mediated cytotoxicity|inhibition of neutrophil mediated cytotoxicity							mah	2009-10-01T02:20:17Z					biological_process											owl:Class	
GO:0007120	biolink:NamedThing	axial cellular bud site selection	The process of defining the next site of bud emergence adjacent to the last site of bud emergence on a budding cell.	tmpzr1t_l9r_go_relaxed.owl	axial budding|axial bud site selection													biological_process											owl:Class	
GO:0103004	biolink:NamedThing	9,10-epoxystearate hydroxylase activity	Catalysis of the reaction: H+ + 9,10-epoxystearate + O2 + NADPH <=> 9,10-epoxy-18-hydroxystearate + H2O + NADP.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-9805									molecular_function											owl:Class	
GO:0050984	biolink:NamedThing	peptidyl-serine sulfation	The sulfation of peptidyl-serine to form peptidyl-O-sulfo-L-serine.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0361									biological_process											owl:Class	
GO:0060111	biolink:NamedThing	alae of collagen and cuticulin-based cuticle extracellular matrix	Raised, thickened cuticular ridges that run longitudinally, and in parallel, along the left and right sides of the animal. The alae lie above the hypodermal cells known as the lateral seam cells. In C. elegans, alae are produced in L1 larvae, dauer larvae and adult stage animals, where they consist of three, five, and three ridges of distinct morphology, respectively.	tmpzr1t_l9r_go_relaxed.owl	alae of collagen and cuticulin-based exoskeleton extracellular matrix													cellular_component											owl:Class	
GO:0102546	biolink:NamedThing	mannosylglycerate hydrolase activity	Catalysis of the reaction: H2O + 2-(alpha-D-mannosyl)-D-glycerate <=> alpha-D-mannose + D-glycerate.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-14900|RHEA:58456									molecular_function											owl:Class	
GO:0016934	biolink:NamedThing	extracellularly glycine-gated chloride channel activity	Enables the transmembrane transfer of a chloride ion by a channel that opens when glycine is bound by the channel complex or one of its constituent parts on the extracellular side of the plasma membrane.	tmpzr1t_l9r_go_relaxed.owl	glycine-inhibited chloride channel activity|extracellular-glycine-gated chloride channel activity|glycine receptor				Reactome:R-HSA-975389							GO:0004891		molecular_function											owl:Class	
GO:0016933	biolink:NamedThing	extracellularly glycine-gated ion channel activity	Enables the transmembrane transfer of an ion by a channel that opens when glycine is bound by the channel complex or one of its constituent parts on the extracellular side of the plasma membrane.	tmpzr1t_l9r_go_relaxed.owl	extracellular-glycine-gated ion channel activity|glycine receptor													molecular_function											owl:Class	
GO:0008143	biolink:NamedThing	poly(A) binding	Binding to a sequence of adenylyl residues in an RNA molecule, such as the poly(A) tail, a sequence of adenylyl residues at the 3' end of eukaryotic mRNA.	tmpzr1t_l9r_go_relaxed.owl	poly(A) binding, within an RNA molecule|polyadenylate binding|poly(rA) binding|poly-A binding													molecular_function											owl:Class	
GO:0070717	biolink:NamedThing	poly-purine tract binding	Binding to a stretch of purines (adenine or guanine) in an RNA molecule.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-06-10T03:32:15Z					molecular_function											owl:Class	
GO:0035879	biolink:NamedThing	plasma membrane lactate transport	The directed movement of lactate across a plasma membrane.	tmpzr1t_l9r_go_relaxed.owl	lactate plasma membrane transport							bf	2011-05-31T02:54:32Z					biological_process											owl:Class	
GO:0140493	biolink:NamedThing	very long-chain fatty acid beta-oxidation	A fatty acid beta-oxidation pathway acting on fatty acid which has a chain length greater than C22 in which the initial step, which converts an acyl-CoA to a trans-2-enoyl-CoA, is catalyzed by acyl-CoA oxidase; the electrons removed by oxidation pass directly to oxygen and produce hydrogen peroxide, which is cleaved by peroxisomal catalases. Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and ends when only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively).	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/19735						pg	2020-07-10T08:39:22Z					biological_process											owl:Class	
GO:0042760	biolink:NamedThing	very long-chain fatty acid catabolic process	The chemical reactions and pathways resulting in the breakdown of a fatty acid which has a chain length greater than C22.	tmpzr1t_l9r_go_relaxed.owl	very-long-chain fatty acid catabolism|very-long-chain fatty acid catabolic process|very-long-chain fatty acid breakdown|very-long-chain fatty acid degradation													biological_process											owl:Class	
GO:0001517	biolink:NamedThing	N-acetylglucosamine 6-O-sulfotransferase activity	Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + N-acetyl-D-glucosamine = adenosine 3',5'-bisphosphate + N-acetyl-D-glucosamine 6-sulfate.	tmpzr1t_l9r_go_relaxed.owl	N-acetylglucosamine 6-O-sulphotransferase activity				Reactome:R-HSA-6786012|Reactome:R-HSA-3656269|Reactome:R-HSA-2046222									molecular_function											owl:Class	
GO:0150066	biolink:NamedThing	negative regulation of deacetylase activity	Any process that stops, prevents or reduces the frequency, rate or extent of deacetylase activity.	tmpzr1t_l9r_go_relaxed.owl								bc	2018-07-23T12:37:57Z					biological_process											owl:Class	
GO:1903752	biolink:NamedThing	positive regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide	Any process that activates or increases the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to hydrogen peroxide.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide|up regulation of intrinsic apoptotic signaling pathway in response to H2O2|activation of hydrogen peroxide-induced intrinsic apoptotic signaling pathway|up-regulation of intrinsic apoptotic signaling pathway in response to H2O2|positive regulation of intrinsic apoptotic signaling pathway in response to H2O2|up regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide|up-regulation of hydrogen peroxide-induced intrinsic apoptotic signaling pathway|positive regulation of H2O2-induced intrinsic apoptotic signaling pathway|upregulation of H2O2-induced intrinsic apoptotic signaling pathway|up-regulation of H2O2-induced intrinsic apoptotic signaling pathway|up regulation of H2O2-induced intrinsic apoptotic signaling pathway|activation of H2O2-induced intrinsic apoptotic signaling pathway|positive regulation of hydrogen peroxide-induced intrinsic apoptotic signaling pathway|upregulation of intrinsic apoptotic signaling pathway in response to H2O2|activation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide|upregulation of hydrogen peroxide-induced intrinsic apoptotic signaling pathway|up regulation of hydrogen peroxide-induced intrinsic apoptotic signaling pathway|upregulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide|activation of intrinsic apoptotic signaling pathway in response to H2O2							krc	2014-12-12T23:04:46Z					biological_process											owl:Class	
GO:0047619	biolink:NamedThing	acylcarnitine hydrolase activity	Catalysis of the reaction: O-acylcarnitine + H2O = a fatty acid + L-carnitine.	tmpzr1t_l9r_go_relaxed.owl	HACH|O-acylcarnitine acylhydrolase activity|palmitoylcarnitine hydrolase activity|long-chain acyl-L-carnitine hydrolase activity|carnitine ester hydrolase activity|palmitoyl-L-carnitine hydrolase activity|palmitoyl carnitine hydrolase activity|high activity acylcarnitine hydrolase activity				RHEA:17101|EC:3.1.1.28|MetaCyc:ACYLCARNITINE-HYDROLASE-RXN									molecular_function											owl:Class	
GO:0031697	biolink:NamedThing	beta-1 adrenergic receptor binding	Binding to a beta-1 adrenergic receptor.	tmpzr1t_l9r_go_relaxed.owl	beta-1 adrenergic receptor ligand													molecular_function											owl:Class	
GO:0002159	biolink:NamedThing	desmosome assembly	A cellular process that results in the aggregation, arrangement and bonding together of a set of components to form a desmosome. A desmosome is a patch-like intercellular junction found in vertebrate tissues, consisting of parallel zones of two cell membranes, separated by an space of 25-35 nm, and having dense fibrillar plaques in the subjacent cytoplasm.	tmpzr1t_l9r_go_relaxed.owl						Desmosomes link two cells together; hemidesmosomes attach one cell to the extracellular matrix.		hjd	2010-02-09T10:46:30Z					biological_process											owl:Class	
GO:0140204	biolink:NamedThing	pyridoxal import across plasma membrane	The directed movement of pyridoxal from outside of a cell, across the plasma membrane and into the cytosol.	tmpzr1t_l9r_go_relaxed.owl								pg	2018-02-21T19:17:27Z					biological_process											owl:Class	
GO:0019522	biolink:NamedThing	ketogluconate metabolic process	The chemical reactions and pathways involving ketogluconate, the anion of ketogluconic acid, an aldonic acid derived from glucose containing a ketonic carbonyl group.	tmpzr1t_l9r_go_relaxed.owl	ketogluconate metabolism				MetaCyc:KETOGLUCONMET-PWY									biological_process											owl:Class	
GO:0047279	biolink:NamedThing	sn-glycerol-3-phosphate 1-galactosyltransferase activity	Catalysis of the reaction: sn-glycerol 3-phosphate + UDP-D-galactose = 1-O-alpha-D-galactosyl-sn-glycerol 3-phosphate + H(+) + UDP.	tmpzr1t_l9r_go_relaxed.owl	uridine diphosphogalactose-glycerol phosphate galactosyltransferase activity|glycerol 3-phosphate 1alpha-galactosyltransferase activity|UDPgalactose:sn-glycerol-3-phosphate alpha-D-galactosyltransferase activity|UDP-Gal:sn-glycero-3-phosphoric acid 1-alpha-galactosyl-transferase activity|UDPgalactose:sn-glycerol-3-phosphate 1-alpha-D-galactosyltransferase activity|UDP-galactose:sn-glycerol-3-phosphate 1-alpha-D-galactosyltransferase activity|isofloridoside-phosphate synthase activity				KEGG_REACTION:R00854|RHEA:20341|MetaCyc:2.4.1.96-RXN|EC:2.4.1.96									molecular_function											owl:Class	
GO:0052078	biolink:NamedThing	suppression by symbiont of defense-related host MAP kinase-mediated signal transduction pathway	Any process in which a symbiont stops, prevents, or reduces the frequency, rate or extent of a host MAP kinase-mediated signal transduction pathway during the host innate immune response. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	down regulation by symbiont of defense-related host MAP kinase-mediated signal transduction pathway|negative regulation by organism of defense-related host MAPK-mediated signal transduction pathway|negative regulation by symbiont of defense-related host MAP kinase-mediated signal transduction pathway|suppression by organism of defense-related host MAP kinase-mediated signal transduction pathway|down-regulation by symbiont of defense-related host MAP kinase-mediated signal transduction pathway|inhibition by symbiont of defense-related host MAP kinase-mediated signal transduction pathway|downregulation by symbiont of defense-related host MAP kinase-mediated signal transduction pathway|negative regulation by organism of defense-related MAP kinase-mediated signal transduction pathway in other organism involved in symbiotic interaction|negative regulation by organism of defense-related host mitogen-activated protein kinase-mediated signal transduction pathway	https://github.com/geneontology/go-ontology/issues/19235										GO:0052275		biological_process											owl:Class	
GO:0031207	biolink:NamedThing	Sec62/Sec63 complex	A protein complex involved in the posttranslational targeting of proteins to the ER. In yeast, it is a tetrameric complex consisting of Sec62p, Sec63p, Sec71p and Sec72p.	tmpzr1t_l9r_go_relaxed.owl	ER protein translocation subcomplex|Sec62/63 complex													cellular_component											owl:Class	
GO:0005500	biolink:NamedThing	juvenile hormone binding	Binding to a juvenile hormone, a sesquiterpenoid derivative that function to maintain the larval state of insects at molting and that may be required for other processes, e.g. oogenesis.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0120142	biolink:NamedThing	positive regulation of ecdysone receptor-mediated signaling pathway	Any process that activates or increases the frequency, rate or extent of any ecdysone receptor-mediated signaling pathway.	tmpzr1t_l9r_go_relaxed.owl								krc	2018-03-22T17:25:00Z					biological_process											owl:Class	
GO:1900352	biolink:NamedThing	negative regulation of methanofuran biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of methanofuran biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	inhibition of methanofuran biosynthetic process|inhibition of methanofuran biosynthesis|negative regulation of methanofuran biosynthesis|down regulation of methanofuran biosynthesis|down-regulation of methanofuran biosynthetic process|down regulation of methanofuran biosynthetic process|downregulation of methanofuran biosynthetic process|downregulation of methanofuran biosynthesis|down-regulation of methanofuran biosynthesis							tt	2012-04-06T02:14:00Z					biological_process											owl:Class	
GO:0072549	biolink:NamedThing	monocoumaroyl dicaffeoyl spermidine meta-hydroxylase activity	Catalysis of the reaction: monocoumaroyl dicaffeoyl spermidine + NADPH + O2 = tricaffeoyl spermidine + NADP+ + H2O.	tmpzr1t_l9r_go_relaxed.owl								mah	2011-01-25T02:58:04Z					molecular_function											owl:Class	
GO:0022036	biolink:NamedThing	rhombomere cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a rhombomere cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0061965	biolink:NamedThing	positive regulation of entry into reproductive diapause	Any process that activates or increases the rate or extent of the dormancy process that results in entry into reproductive diapause. Reproductive diapause is a form of diapause where the organism itself will remain fully active, including feeding and other routine activities, but the reproductive organs experience a tissue-specific reduction in metabolism, with characteristic triggering and releasing stimuli.	tmpzr1t_l9r_go_relaxed.owl								dph	2018-02-05T15:06:51Z					biological_process											owl:Class	
GO:0002481	biolink:NamedThing	antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent	The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class Ib protein complex following intracellular transport via a TAP (transporter associated with antigen processing) pathway. The peptide is typically a fragment of a larger exogenous protein which has been degraded within the cell and is dependent on TAP transport from the cytosol to ER for association with the MHC class Ib molecule. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E gene family.	tmpzr1t_l9r_go_relaxed.owl	TAP-dependent antigen processing and presentation of exogenous peptide antigen via MHC class Ib|TAP-dependent exogenous peptide antigen processing and presentation via MHC class Ib|exogenous peptide antigen processing and presentation via MHC class Ib, TAP-dependent													biological_process											owl:Class	
GO:0002477	biolink:NamedThing	antigen processing and presentation of exogenous peptide antigen via MHC class Ib	The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class Ib protein complex. The peptide is typically a fragment of a larger exogenous protein which has been degraded within the cell. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E gene family.	tmpzr1t_l9r_go_relaxed.owl	exogenous peptide antigen processing and presentation via MHC class Ib													biological_process											owl:Class	
GO:1900972	biolink:NamedThing	negative regulation of sarcinapterin biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of sarcinapterin biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of sarcinapterin anabolism|down regulation of sarcinapterin biosynthetic process|negative regulation of sarcinapterin biosynthesis|down-regulation of sarcinapterin biosynthetic process|down regulation of sarcinapterin synthesis|down-regulation of sarcinapterin formation|down regulation of sarcinapterin formation|down regulation of sarcinapterin anabolism|downregulation of sarcinapterin biosynthetic process|negative regulation of sarcinapterin anabolism|inhibition of sarcinapterin synthesis|inhibition of sarcinapterin anabolism|inhibition of sarcinapterin biosynthesis|downregulation of sarcinapterin biosynthesis|down-regulation of sarcinapterin synthesis|inhibition of sarcinapterin formation|down-regulation of sarcinapterin biosynthesis|down regulation of sarcinapterin biosynthesis|negative regulation of sarcinapterin synthesis|downregulation of sarcinapterin anabolism|inhibition of sarcinapterin biosynthetic process|downregulation of sarcinapterin formation|downregulation of sarcinapterin synthesis|negative regulation of sarcinapterin formation							tt	2012-06-14T04:00:06Z					biological_process											owl:Class	
GO:0001572	biolink:NamedThing	lactosylceramide biosynthetic process	The chemical reactions and pathways resulting in the formation of lactosylceramides, Gal-beta-(1->4)-Glc-beta(1->1') ceramides, any compound formed by the replacement of the glycosidic C1 hydroxyl group of lactose by a ceramide group. They are the precursors of both gangliosides and globosides.	tmpzr1t_l9r_go_relaxed.owl	lactosylceramide anabolism|lactosylceramide synthesis|lactosylceramide biosynthesis|lactosylceramide formation													biological_process											owl:Class	
GO:0007319	biolink:NamedThing	negative regulation of oskar mRNA translation	Any process that stops, prevents or reduces the rate that oskar mRNAs are effectively translated into protein.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of oskar mRNA translation|inhibition of oskar mRNA translation|down regulation of oskar mRNA translation|downregulation of oskar mRNA translation													biological_process											owl:Class	
GO:0051067	biolink:NamedThing	dihydropteridine metabolic process	The chemical reactions and pathways involving 6,7-dihydropteridine, a bicyclic compound with the formula C6H6N4.	tmpzr1t_l9r_go_relaxed.owl	dihydropteridine metabolism|6,7-dihydropteridine metabolic process|dihydropteridine reduction													biological_process											owl:Class	
GO:0004598	biolink:NamedThing	peptidylamidoglycolate lyase activity	Catalysis of the reaction: peptidylamidoglycolate = peptidyl amide + glyoxylate.	tmpzr1t_l9r_go_relaxed.owl	peptidyl-alpha-hydroxyglycine alpha-amidating lyase activity|PGL|HGAD|alpha-hydroxyglycine amidating dealkylase activity|peptidylamidoglycolate peptidylamide-lyase (glyoxylate-forming)|peptidylamidoglycolate peptidylamide-lyase activity|PAL				MetaCyc:PEPTIDYLAMIDOGLYCOLATE-LYASE-RXN|RHEA:20924|EC:4.3.2.5									molecular_function											owl:Class	
GO:0031451	biolink:NamedThing	positive regulation of slow-twitch skeletal muscle fiber contraction	Any process that activates or increases the frequency, rate or extent of slow-twitch skeletal muscle contraction.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of slow-twitch skeletal muscle contraction|positive regulation of slow-twitch skeletal muscle contraction|stimulation of slow-twitch skeletal muscle contraction|activation of slow-twitch skeletal muscle contraction|upregulation of slow-twitch skeletal muscle contraction|up regulation of slow-twitch skeletal muscle contraction													biological_process											owl:Class	
GO:0042820	biolink:NamedThing	vitamin B6 catabolic process	The chemical reactions and pathways resulting in the breakdown of any of the vitamin B6 compounds; pyridoxal, pyridoxamine and pyridoxine and the active form, pyridoxal phosphate.	tmpzr1t_l9r_go_relaxed.owl	vitamin B6 degradation|vitamin B6 breakdown|vitamin B6 catabolism													biological_process											owl:Class	
GO:0090516	biolink:NamedThing	L-serine transmembrane import into vacuole	The directed movement of L-serine into the vacuole across the vacuolar membrane.	tmpzr1t_l9r_go_relaxed.owl								tb	2012-12-14T11:25:52Z					biological_process											owl:Class	
GO:1904108	biolink:NamedThing	protein localization to ciliary inversin compartment	A process in which a protein is transported to, or maintained in, a location within a ciliary inversin compartment.	tmpzr1t_l9r_go_relaxed.owl	protein localization in ciliary inversin compartment|protein localisation in ciliary inversin compartment|protein localisation to ciliary inversin compartment							kmv	2015-04-01T20:54:26Z					biological_process											owl:Class	
GO:1990316	biolink:NamedThing	Atg1/ULK1 kinase complex	A protein complex consisting of Atg1 (or Atg1 homologs e.g. ULK1, ULK2 in mammals) and Atg13 along with other proteins that regulate its function (e.g. Atg17 in yeast or RB1CC1(FIP200) in mammals). This complex has serine/threonine protein kinase activity and is involved in autophagosome formation.	tmpzr1t_l9r_go_relaxed.owl	ATG1 kinase complex|ATG1/ULK1 signaling complex|ULK1 complex|Atg1p signalling complex|ULK1-ATG13-FIP200 complex|ULK1-ATG13-RB1CC1 complex|ULK complex|ATG1-ATG13 complex|autophagy-initiation complex|ULK1 signaling complex							bhm	2014-03-14T10:55:11Z			GO:0034273|GO:0070969		cellular_component											owl:Class	
GO:0090011	biolink:NamedThing	Wnt signaling pathway involved in primitive streak formation	The series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of the target cell and ending with a change in transcription of target genes that contribute to the formation of the primitive streak.	tmpzr1t_l9r_go_relaxed.owl	Wnt receptor signalling pathway involved in primitive streak formation|Wnt receptor signaling pathway involved in primitive streak formation|Wnt-activated signaling pathway involved in primitive streak formation							tb	2009-07-29T10:44:53Z					biological_process											owl:Class	
GO:0098675	biolink:NamedThing	intrinsic component of neuronal dense core vesicle membrane	The component of the neuronal dense core vesicle membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.	tmpzr1t_l9r_go_relaxed.owl	intrinsic to neuronal dense core granule membrane							dos	2017-01-17T16:22:44Z					cellular_component											owl:Class	
GO:1904152	biolink:NamedThing	regulation of retrograde protein transport, ER to cytosol	Any process that modulates the frequency, rate or extent of retrograde protein transport, ER to cytosol.	tmpzr1t_l9r_go_relaxed.owl	regulation of protein dislocation from ER|regulation of retrograde protein transport, endoplasmic reticulum to cytosol|regulation of protein retrotranslocation from ER							bf	2015-04-15T09:23:06Z					biological_process											owl:Class	
GO:0009864	biolink:NamedThing	induced systemic resistance, jasmonic acid mediated signaling pathway	The series of molecular signals mediated by jasmonic acid involved in induced systemic resistance.	tmpzr1t_l9r_go_relaxed.owl	jasmonic acid mediated signaling pathway (induced systemic resistance)|induced systemic resistance, jasmonic acid mediated signalling pathway													biological_process											owl:Class	
GO:0008607	biolink:NamedThing	phosphorylase kinase regulator activity	Modulation of the activity of the enzyme phosphorylase kinase.	tmpzr1t_l9r_go_relaxed.owl	phosphorylase kinase, intrinsic regulator activity				EC:2.7.1.-									molecular_function											owl:Class	
GO:0018356	biolink:NamedThing	protein-phycobiliviolin linkage via S-phycobiliviolin-L-cysteine	The linkage of the chromophore phycobiliviolin to phycoerythrocyanin via S-phycobiliviolin-L-cysteine.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0258							GO:0018382		biological_process											owl:Class	
GO:1901428	biolink:NamedThing	regulation of syringal lignin biosynthetic process	Any process that modulates the frequency, rate or extent of syringal lignin biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of S-lignin biosynthetic process|regulation of syringal lignin anabolism|regulation of syringal lignin biosynthesis|regulation of syringal lignin formation|regulation of syringal lignin synthesis							tb	2012-10-01T20:13:41Z					biological_process											owl:Class	
GO:0090680	biolink:NamedThing	disruption by virus of host outer membrane	A process by which a virus has a negative effect on the functioning of a host outer membrane.	tmpzr1t_l9r_go_relaxed.owl								tb	2016-05-04T15:52:02Z					biological_process											owl:Class	
GO:0044662	biolink:NamedThing	disruption by virus of host cell membrane	A process by which a virus has a negative effect on the functioning of a host cellular membrane.	tmpzr1t_l9r_go_relaxed.owl	disruption by organism of host cell membrane							jl	2012-08-01T13:44:52Z					biological_process											owl:Class	
GO:0075216	biolink:NamedThing	positive regulation of spore encystment on host	Any process that activates, maintains or increases the frequency, rate or extent of spore encystment on host. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0120123	biolink:NamedThing	ubiquitin activating enzyme complex	A protein complex responsible for the catalysis of the reaction: E1 + ubiquitin + ATP--> E1-ubiquitin + AMP + PPi, where the E1-ubiquitin linkage is a thioester bond between the C-terminal glycine of Ub and a sulfhydryl side group of an E1 cysteine residue. This is the first step in a cascade of reactions in which ubiquitin is ultimately added to a protein substrate.	tmpzr1t_l9r_go_relaxed.owl	E1 ubiquitin-activating enzyme|E1 complex							krc	2018-01-29T19:28:56Z					cellular_component											owl:Class	
GO:0003018	biolink:NamedThing	vascular process in circulatory system	A circulatory process that occurs at the level of the vasculature.	tmpzr1t_l9r_go_relaxed.owl	vasculature process													biological_process											owl:Class	
GO:0032263	biolink:NamedThing	GMP salvage	Any process which produces guanosine monophosphate from derivatives of it, without de novo synthesis.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0006177	biolink:NamedThing	GMP biosynthetic process	The chemical reactions and pathways resulting in the formation of GMP, guanosine monophosphate.	tmpzr1t_l9r_go_relaxed.owl	GMP biosynthesis|GMP anabolism|GMP synthesis|GMP formation													biological_process											owl:Class	
GO:0051686	biolink:NamedThing	establishment of ER localization	The directed movement of the endoplasmic reticulum to a specific location.	tmpzr1t_l9r_go_relaxed.owl	establishment of ER localisation|establishment of endoplasmic reticulum localization													biological_process											owl:Class	
GO:0006500	biolink:NamedThing	N-terminal protein palmitoylation	The covalent attachment of a palmitoyl group to the N-terminal amino acid residue of a protein.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0047508	biolink:NamedThing	(R)-2-methylmalate dehydratase activity	Catalysis of the reaction: (R)-citramalate = 2-methylmaleate + H(2)O.	tmpzr1t_l9r_go_relaxed.owl	citramalate hydro-lyase activity|(R)-2-methylmalate hydro-lyase activity|citraconate hydratase activity|(-)-citramalate hydro-lyase activity|citraconase activity|(R)-2-methylmalate hydro-lyase (2-methylmaleate-forming)				RHEA:22332|KEGG_REACTION:R03896|EC:4.2.1.35|MetaCyc:R-2-METHYLMALATE-DEHYDRATASE-RXN									molecular_function											owl:Class	
GO:0045686	biolink:NamedThing	negative regulation of glial cell differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of glia cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of glia cell differentiation|inhibition of glial cell differentiation|downregulation of glial cell differentiation|down-regulation of glial cell differentiation|down regulation of glial cell differentiation|negative regulation of neuroglia differentiation													biological_process											owl:Class	
GO:0071049	biolink:NamedThing	nuclear retention of pre-mRNA with aberrant 3'-ends at the site of transcription	The process involved in retention of mRNAs that have incorrectly formed 3'-ends within the nucleus at the site of transcription.	tmpzr1t_l9r_go_relaxed.owl								krc	2009-08-11T02:40:56Z					biological_process											owl:Class	
GO:0019643	biolink:NamedThing	reductive tricarboxylic acid cycle	A pathway leading to the fixation of two molecules of CO2 and the production of one molecule of acetyl-CoA; essentially the oxidative TCA cycle running in reverse. Acetyl-CoA is reductively carboxylated to pyruvate, from which all other central metabolites can be formed. Most of the enzymes of reductive and oxidative TCA cycle are shared, with the exception of three key enzymes that allow the cycle to run in reverse: ATP citrate lyase, 2-oxoglutarate:ferredoxin oxidoreductase, and fumarate reductase. 2-oxoglutarate:ferredoxin oxidoreductase catalyzes the carboxylation of succinyl-CoA to 2-oxoglutarate, ATP citrate lyase the ATP-dependent cleavage of citrate to acetyl-CoA and oxaloacetate, and fumarate reductase the reduction of fumarate forming succinate.	tmpzr1t_l9r_go_relaxed.owl	reductive citric acid pathway|reductive carboxylic acid cycle|reductive carboxylate cycle|reductive TCA cycle|reductive Kreb's cycle				MetaCyc:REDCITCYC|MetaCyc:P23-PWY							GO:0019644		biological_process											owl:Class	
GO:0035871	biolink:NamedThing	protein K11-linked deubiquitination	A protein deubiquitination process in which a K11-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 11 of the ubiquitin monomers, is removed from a protein.	tmpzr1t_l9r_go_relaxed.owl	protein K11-linked deubiquitylation|protein K11-linked deubiquitinylation							bf	2011-05-26T11:44:13Z					biological_process											owl:Class	
GO:0071011	biolink:NamedThing	precatalytic spliceosome	A spliceosomal complex that is formed by the recruitment of a preassembled U5-containing tri-snRNP to the prespliceosome. Although all 5 snRNPs are present, the precatalytic spliceosome is catalytically inactive. The precatalytic spliceosome includes many proteins in addition to those found in the associated snRNPs.	tmpzr1t_l9r_go_relaxed.owl	mammalian spliceosomal complex B|yeast spliceosomal complex A2-1|mammalian spliceosomal complex B1							mah	2009-07-30T12:00:35Z					cellular_component											owl:Class	
GO:0071848	biolink:NamedThing	positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling	Any TNFSF11-mediated signaling process that increases the rate, frequency, or extent of the ERK1 and ERK2 cascade.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signalling|positive regulation of ERK1 and ERK2 cascade via RANKL-mediated signaling							mah	2010-09-10T02:25:31Z					biological_process											owl:Class	
GO:0046848	biolink:NamedThing	hydroxyapatite binding	Binding to hydroxyapatite, the calcium phosphate mineral of formula Ca10(PO4)6(OH)2 found both in rocks of nonorganic origin and as a component of bone and dentin.	tmpzr1t_l9r_go_relaxed.owl	hydroxylapatite binding													molecular_function											owl:Class	
GO:0007291	biolink:NamedThing	sperm individualization	The resolution of the male germline syncytium or cyst into individual gametes by packaging each spermatid into its own plasma membrane.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0007349	biolink:NamedThing	cellularization	The separation of a multi-nucleate cell or syncytium into individual cells. An example of this is found in Drosophila melanogaster embryo development.	tmpzr1t_l9r_go_relaxed.owl												GO:0009796		biological_process											owl:Class	
GO:0007374	biolink:NamedThing	posterior midgut invagination	Formation of a cup-shaped invagination at the posterior end of the embryo, bringing the posterior midgut and hindgut primordia into the interior.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0001801	biolink:NamedThing	positive regulation of type IIb hypersensitivity	Any process that activates or increases the frequency, rate or extent of type IIb hypersensitivity, a type of inflammatory response.	tmpzr1t_l9r_go_relaxed.owl	up regulation of type IIb hypersensitivity|stimulation of type IIb hypersensitivity|upregulation of type IIb hypersensitivity|up-regulation of type IIb hypersensitivity|activation of type IIb hypersensitivity													biological_process											owl:Class	
GO:0009921	biolink:NamedThing	auxin efflux carrier complex	The protein complex associated with the plasma membrane of certain plant cells (e.g. root cortex, epidermal cells) that functions to transport auxin out of the cell.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0046711	biolink:NamedThing	GDP biosynthetic process	The chemical reactions and pathways resulting in the formation of GDP, guanosine 5'-diphosphate.	tmpzr1t_l9r_go_relaxed.owl	GDP anabolism|GDP synthesis|GDP biosynthesis|GDP formation													biological_process											owl:Class	
GO:0010752	biolink:NamedThing	regulation of cGMP-mediated signaling	Any process that modulates the rate, frequency or extent of cGMP-mediated signaling. cGMP-mediated signaling is a series of molecular signals in which a cell uses cyclic GMP to convert an extracellular signal into a response.	tmpzr1t_l9r_go_relaxed.owl	regulation of cGMP-mediated signalling													biological_process											owl:Class	
GO:1901268	biolink:NamedThing	cephalosporin C biosynthetic process	The chemical reactions and pathways resulting in the formation of cephalosporin C.	tmpzr1t_l9r_go_relaxed.owl	cephalosporin C synthesis|cephalosporin C anabolism|cephalosporin C biosynthesis|cephalosporin C formation							yaf	2012-08-17T14:26:31Z					biological_process											owl:Class	
GO:0002242	biolink:NamedThing	defense response to parasitic plant	Reactions triggered in response to the presence of a parasitic plant that act to protect an organism.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0006603	biolink:NamedThing	phosphocreatine metabolic process	The chemical reactions and pathways involving phosphocreatine, a phosphagen of creatine present in high concentration in striated muscle which is synthesized and broken down by creatine phosphokinase to buffer ATP concentration. It acts as an immediate energy reserve for muscle.	tmpzr1t_l9r_go_relaxed.owl	phosphocreatine metabolism													biological_process											owl:Class	
GO:0017081	biolink:NamedThing	chloride channel regulator activity	Binds to and modulates the activity of a chloride channel.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-383190									molecular_function											owl:Class	
GO:0106352	biolink:NamedThing	aspartate dehydrogenase NADP activity	Catalysis of the reaction: L-aspartate + H2O + NADP+ = oxaloacetate + NH3 + NADPH+ H+.	tmpzr1t_l9r_go_relaxed.owl					RHEA:11784			hjd	2021-01-20T17:40:23Z					molecular_function											owl:Class	
GO:2000903	biolink:NamedThing	cellooligosaccharide catabolic process	The chemical reactions and pathways resulting in the breakdown of a cellooligosaccharide.	tmpzr1t_l9r_go_relaxed.owl	cellooligosaccharide catabolism							jl	2011-07-28T03:21:49Z					biological_process											owl:Class	
GO:0014837	biolink:NamedThing	myoblast fate determination involved in skeletal muscle regeneration	The process in which a satellite cell becomes capable of differentiating autonomously into a myoblast regardless of its environment; upon determination, the cell fate cannot be reversed. This occurs as part of skeletal muscle regeneration. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0007518	biolink:NamedThing	myoblast fate determination	The cell fate determination process in which a cell becomes capable of differentiating autonomously into a myoblast regardless of its environment; upon determination, the cell fate cannot be reversed. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1900554	biolink:NamedThing	asperfuranone biosynthetic process	The chemical reactions and pathways resulting in the formation of asperfuranone.	tmpzr1t_l9r_go_relaxed.owl	asperfuranone anabolism|asperfuranone biosynthesis|asperfuranone formation|asperfuranone synthesis							di	2012-05-15T01:31:58Z					biological_process											owl:Class	
GO:0050771	biolink:NamedThing	negative regulation of axonogenesis	Any process that stops, prevents, or reduces the frequency, rate or extent of axonogenesis.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of axonogenesis|downregulation of axonogenesis|inhibition of axonogenesis|down regulation of axonogenesis													biological_process											owl:Class	
GO:0008355	biolink:NamedThing	olfactory learning	Any process in an organism in which a relatively long-lasting adaptive behavioral change occurs in response to (repeated) exposure to an olfactory cue.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0042048	biolink:NamedThing	olfactory behavior	The behavior of an organism in response to an odor.	tmpzr1t_l9r_go_relaxed.owl	behavioural response to odour|behavioral response to scent|behavioral response to smell|behavioural response to smell|olfactory behaviour|behavioural response to scent													biological_process											owl:Class	
GO:0070608	biolink:NamedThing	regulation of cell wall (1->3)-alpha-glucan biosynthetic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds, found in the walls of cells.	tmpzr1t_l9r_go_relaxed.owl	regulation of cell wall 1,3-alpha-glucan biosynthesis|regulation of cell wall alpha-1,3-glucan formation|regulation of cell wall alpha-1,3-glucan biosynthesis|regulation of cell wall 1,3-alpha-glucan synthesis|regulation of cell wall 1,3-alpha-glucan formation|regulation of cell wall alpha-1,3-glucan anabolism|regulation of cell wall 1,3-alpha-glucan anabolism|regulation of cell wall alpha-1,3-glucan biosynthetic process|regulation of cell wall 1,3-alpha-glucan biosynthetic process|regulation of cell wall alpha-1,3-glucan synthesis							mah	2009-04-29T01:27:15Z					biological_process											owl:Class	
GO:0070606	biolink:NamedThing	regulation of (1->3)-alpha-glucan biosynthetic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds.	tmpzr1t_l9r_go_relaxed.owl	regulation of alpha-1,3 glucan synthesis|regulation of alpha-1,3 glucan formation|regulation of 1,3-alpha-glucan biosynthetic process|regulation of 1,3-alpha-glucan biosynthesis|regulation of 1,3-alpha-glucan formation|regulation of alpha-1,3 glucan biosynthesis|regulation of alpha-1,3 glucan biosynthetic process|regulation of 1,3-alpha-glucan synthesis|regulation of alpha-1,3 glucan anabolism|regulation of 1,3-alpha-glucan anabolism							mah	2009-04-29T01:22:45Z					biological_process											owl:Class	
GO:0004831	biolink:NamedThing	tyrosine-tRNA ligase activity	Catalysis of the reaction: L-tyrosine + ATP + tRNA(Tyr) = L-tyrosyl-tRNA(Tyr) + AMP + diphosphate + 2 H(+).	tmpzr1t_l9r_go_relaxed.owl	tyrosyl-transfer ribonucleate synthetase activity|L-tyrosine-tRNATyr ligase (AMP-forming)|tyrosine tRNA synthetase activity|tyrosyl-tRNA synthetase activity|L-tyrosine:tRNATyr ligase (AMP-forming)|tyrosyl-transfer ribonucleic acid synthetase activity|tyrosine-transfer ribonucleate synthetase activity|tyrosyl-transfer RNA synthetase activity|tyrosine-transfer RNA ligase activity|L-tyrosine-tRNA(Tyr) ligase (AMP-forming) activity|tyrosine translase activity|tyrosyl-tRNA ligase activity				RHEA:10220|MetaCyc:TYROSINE--TRNA-LIGASE-RXN|Reactome:R-HSA-380170|Reactome:R-HSA-379980|KEGG_REACTION:R02918|EC:6.1.1.1									molecular_function											owl:Class	
GO:0031272	biolink:NamedThing	regulation of pseudopodium assembly	Any process that modulates the frequency, rate or extent of the assembly of pseudopodia.	tmpzr1t_l9r_go_relaxed.owl	regulation of pseudopodium formation													biological_process											owl:Class	
GO:0071490	biolink:NamedThing	cellular response to far red light	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of far red light stimulus. Far red light is electromagnetic radiation of wavelength 700-800nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reversed by exposure to far red light. During the initial phase the phytochrome molecule is only present in the red light absorbing form, but on absorption of red light it changes to a far red light absorbing form, triggering progress through development. An immediate short period of exposure to far red light entirely returns the pigment to its initial state and prevents triggering of the developmental process. A thirty minute break between red and subsequent far red light exposure renders the red light effect irreversible, and development then occurs regardless of whether far red light exposure subsequently occurs.	tmpzr1t_l9r_go_relaxed.owl	cellular response to far red light stimulus							mah	2009-12-18T02:19:40Z					biological_process											owl:Class	
GO:0047881	biolink:NamedThing	estradiol 17-alpha-dehydrogenase activity	Catalysis of the reaction: estradiol-17-alpha + NAD(P)+ = estrone + NAD(P)H + H+.	tmpzr1t_l9r_go_relaxed.owl	17alpha-hydroxysteroid oxidoreductase activity|estradiol 17alpha-oxidoreductase activity|17alpha-estradiol dehydrogenase activity|estradiol 17alpha-dehydrogenase activity|estradiol 17a-dehydrogenase activity|17alpha-hydroxysteroid:NAD(P)+ 17-oxidoreductase activity|17alpha-hydroxy steroid oxidoreductase activity|17alpha-hydroxy steroid dehydrogenase activity				MetaCyc:ESTRADIOL-17-ALPHA-DEHYDROGENASE-RXN|EC:1.1.1.148									molecular_function											owl:Class	
GO:0045169	biolink:NamedThing	fusome	A large intracellular spectrin-rich structure that has been found in insect germline cells and mammalian hematopoietic cells. The fusome is an elongated, branched structure, formed from the spherical spectrosome organelle.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0020003	biolink:NamedThing	symbiont-containing vacuole	Membrane-bounded vacuole within a host cell in which a symbiont organism resides. The vacuole membrane is derived from both the host and symbiont.	tmpzr1t_l9r_go_relaxed.owl	SCV|bacterium-containing vacuole|parasitophorous vacuole|Salmonella-containing vacuole|pathogen-occupied vacuole					Note that this term does not have a relationship to 'vacuole ; GO:0005773' because it does not fit the definition of a vacuole; the parasitophorous vacuole was so named because it resembles a vacuole in the microscope.								cellular_component											owl:Class	
GO:0047626	biolink:NamedThing	adenosylmethionine hydrolase activity	Catalysis of the reaction: S-adenosyl-L-methionine + H(2)O = S-methyl-5'-thioadenosine + L-homoserine + H(+).	tmpzr1t_l9r_go_relaxed.owl	adenosylmethionine lyase activity|adenosyl methionine hydrolase activity|methylmethionine-sulfonium-salt hydrolase activity|S-adenosylmethionine cleaving enzyme activity|S-adenosyl-L-methionine hydrolase activity				RHEA:14645|KEGG_REACTION:R00175|MetaCyc:ADENOSYLMETHIONINE-HYDROLASE-RXN|EC:3.3.1.2									molecular_function											owl:Class	
GO:0016802	biolink:NamedThing	trialkylsulfonium hydrolase activity	Catalysis of the hydrolysis of a thioether bond, -S-.	tmpzr1t_l9r_go_relaxed.owl	thioether hydrolase activity|trialkylsulphonium hydrolase activity				EC:3.3.1.-									molecular_function											owl:Class	
GO:1905797	biolink:NamedThing	negative regulation of intraciliary anterograde transport	Any process that stops, prevents or reduces the frequency, rate or extent of intraciliary anterograde transport.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of intraflagellar anterograde transport|downregulation of intraflagellar anterograde transport|downregulation of intraciliary anterograde transport|down-regulation of intraflagellar anterograde transport|inhibition of intraflagellar anterograde transport|inhibition of intraciliary anterograde transport|down regulation of intraflagellar anterograde transport|down regulation of intraciliary anterograde transport|down-regulation of intraciliary anterograde transport							hbye	2017-01-11T12:55:53Z					biological_process											owl:Class	
GO:1901458	biolink:NamedThing	negative regulation of response to acetate	Any process that stops, prevents or reduces the frequency, rate or extent of response to acetate.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of response to acetate|inhibition of response to acetate|down regulation of response to acetate|downregulation of response to acetate							tt	2012-10-02T14:26:15Z					biological_process											owl:Class	
GO:0002690	biolink:NamedThing	positive regulation of leukocyte chemotaxis	Any process that activates or increases the frequency, rate, or extent of leukocyte chemotaxis.	tmpzr1t_l9r_go_relaxed.owl	activation of leukocyte chemotaxis|positive regulation of leucocyte chemotaxis|up regulation of leukocyte chemotaxis|positive regulation of immune cell chemotaxis|stimulation of leukocyte chemotaxis|upregulation of leukocyte chemotaxis|up-regulation of leukocyte chemotaxis													biological_process											owl:Class	
GO:1901168	biolink:NamedThing	3-chlorocatechol catabolic process	The chemical reactions and pathways resulting in the breakdown of 3-chlorocatechol.	tmpzr1t_l9r_go_relaxed.owl	3-chlorocatechol degradation|3-chlorocatechol breakdown|3-chlorocatechol catabolism							yaf	2012-07-19T09:33:38Z					biological_process											owl:Class	
GO:0102384	biolink:NamedThing	19-O-beta-glucopyranosyl-steviol glucosyltransferase activity	Catalysis of the reaction: 19-O-beta-glucopyranosyl-steviol + UDP-alpha-D-glucose <=> rubusoside + UDP + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-13521									molecular_function											owl:Class	
GO:0070141	biolink:NamedThing	response to UV-A	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-A radiation stimulus. UV-A radiation (UV-A light) spans the wavelengths 315 to 400 nm.	tmpzr1t_l9r_go_relaxed.owl	response to UVA light stimulus|response to UV-A light stimulus|response to UVA radiation stimulus|response to UV-A radiation stimulus													biological_process											owl:Class	
GO:1990856	biolink:NamedThing	methionyl-initiator methionine tRNA binding	Binding to methionine-initator methionine tRNA.	tmpzr1t_l9r_go_relaxed.owl						An example of this is eukaryotic initiation factor 2 complex, which binds the methionyl-initiator methionine tRNA during ternary complex formation. The non-acylated tRNA is not bound.		hjd	2015-09-18T16:56:59Z					molecular_function											owl:Class	
GO:0044530	biolink:NamedThing	supraspliceosomal complex	Multicomponent complex of RNA and proteins that is composed of four active spliceosomes, termed native spliceosomes, connected to each other by the pre-mRNA. The supraspliceosome is the nuclear machine where the pre-mRNA processing takes place, like the 5'-end capping, 3'-end cleavage, splicing and editing.	tmpzr1t_l9r_go_relaxed.owl	supraspliceosome complex							jl	2012-03-15T03:33:08Z					cellular_component											owl:Class	
GO:0043382	biolink:NamedThing	positive regulation of memory T cell differentiation	Any process that activates or increases the frequency, rate or extent of memory T cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of memory T-cell differentiation|up regulation of memory T cell differentiation|positive regulation of memory T-lymphocyte differentiation|positive regulation of memory T cell development|upregulation of memory T cell differentiation|positive regulation of memory T lymphocyte differentiation|stimulation of memory T cell differentiation|up-regulation of memory T cell differentiation|activation of memory T cell differentiation					Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.								biological_process											owl:Class	
GO:0035156	biolink:NamedThing	fusion cell fate specification	The process in which a cell becomes capable of differentiating autonomously into a fusion cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed. Fusion cells allow the interconnection of adjacent tracheal metameres during tracheal tube fusion.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0035153	biolink:NamedThing	epithelial cell type specification, open tracheal system	Allocation of epithelial cells within each migrating branch in an open tracheal system to distinct tracheal cell fates. During the migration phase each branch forms a well-defined number of cell types (including fusion cells, terminal cells and branch cells) at precise positions.	tmpzr1t_l9r_go_relaxed.owl	tracheal epithelial cell type specification|tracheal cell type specification													biological_process											owl:Class	
GO:0001705	biolink:NamedThing	ectoderm formation	The formation of ectoderm during gastrulation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0015717	biolink:NamedThing	triose phosphate transport	The directed movement of triose phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	aldotriose phosphate transport													biological_process											owl:Class	
GO:0034244	biolink:NamedThing	negative regulation of transcription elongation from RNA polymerase II promoter	Any process that stops, prevents, or reduces the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides, catalyzed by RNA polymerase II.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of RNA elongation from RNA polymerase II promoter|negative regulation of gene-specific transcription elongation from RNA polymerase II promoter											GO:0090041		biological_process											owl:Class	
GO:0034243	biolink:NamedThing	regulation of transcription elongation from RNA polymerase II promoter	Any process that modulates the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides, catalyzed by RNA polymerase II.	tmpzr1t_l9r_go_relaxed.owl	regulation of RNA elongation from RNA polymerase II promoter|regulation of gene-specific transcription elongation from RNA polymerase II promoter											GO:0090039		biological_process											owl:Class	
GO:0047893	biolink:NamedThing	flavonol 3-O-glucosyltransferase activity	Catalysis of the reaction: UDP-glucose + a flavonol = UDP + a flavonol 3-O-D-glucoside.	tmpzr1t_l9r_go_relaxed.owl	UDPglucose:flavonol 3-O-D-glucosyltransferase activity|UDPG:flavonoid-3-O-glucosyltransferase activity|UDP-glucose flavonol 3-O-glucosyltransferase activity|UDP-glucose:flavonol 3-O-glucosyltransferase activity|uridine diphosphoglucose-flavonol 3-O-glucosyltransferase activity|UDP-glucose:flavonol 3-O-D-glucosyltransferase activity|GTI				EC:2.4.1.91|MetaCyc:FLAVONOL-3-O-GLUCOSYLTRANSFERASE-RXN|RHEA:22300									molecular_function											owl:Class	
GO:0106373	biolink:NamedThing	3-deoxyglucosone dehydrogenase activity	Catalysis of the reaction: 3-deoxyglucosone + H2O + NAD(+) = 2-dehydro-3-deoxy-D-gluconate + 2 H(+) + NADH.	tmpzr1t_l9r_go_relaxed.owl								hjd	2021-04-12T14:48:12Z					molecular_function											owl:Class	
GO:1903612	biolink:NamedThing	positive regulation of calcium-dependent ATPase activity	Any process that activates or increases the frequency, rate or extent of calcium-dependent ATPase activity.	tmpzr1t_l9r_go_relaxed.owl	upregulation of calcium-dependent ATPase activity|up regulation of calcium-dependent ATPase activity|activation of calcium-dependent ATPase activity|up-regulation of calcium-dependent ATPase activity							sl	2014-11-18T00:43:06Z					biological_process											owl:Class	
GO:0048758	biolink:NamedThing	companion cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a companion cell. The companion cell is the specialized parenchyma cell associated with a sieve-tube member in angiosperm phloem and arising from the same mother cell as the sieve-tube member.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0048760	biolink:NamedThing	plant parenchymal cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a parenchymal cell. Parenchymal cells are the most abundant and versatile cells in plants. They have very few distinguishing characteristics and botanists classify them as any cell type that cannot be assigned to any other structural or functional class. They can redifferentiate and dedifferentiate and are involved in storage, basic metabolism and other processes. The cells are polyhedral, typically with thin, non-lignified cellulose cell walls and nucleate living protoplasm. They vary in size, form, and wall structure.	tmpzr1t_l9r_go_relaxed.owl	parenchymal cell differentiation													biological_process											owl:Class	
GO:0007112	biolink:NamedThing	male meiosis cytokinesis	A cell cycle process that occurs as part of the male meiotic cell cycle and results in the division of the cytoplasm of a cell to produce two daughter cells.	tmpzr1t_l9r_go_relaxed.owl	cytokinesis after male meiosis|cytokinesis involved in male meiotic cell cycle													biological_process											owl:Class	
GO:0016900	biolink:NamedThing	oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces a disulfide molecule.	tmpzr1t_l9r_go_relaxed.owl	oxidoreductase activity, acting on the CH-OH group of donors, disulphide as acceptor				EC:1.1.4.-									molecular_function											owl:Class	
GO:0010172	biolink:NamedThing	embryonic body morphogenesis	The process in which the anatomical structures of the embryonic soma are generated and organized.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0010167	biolink:NamedThing	response to nitrate	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrate stimulus.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0031917	biolink:NamedThing	negative regulation of synaptic metaplasticity	A process that decreases synaptic metaplasticity. Metaplasticity is a higher-order form of plasticity and is manifest as a change in the ability to induce subsequent synaptic plasticity that is the ability of synapses to change as circumstances require.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of synaptic metaplasticity|inhibition of synaptic metaplasticity|down regulation of synaptic metaplasticity|downregulation of synaptic metaplasticity													biological_process											owl:Class	
GO:0031916	biolink:NamedThing	regulation of synaptic metaplasticity	A process that modulates synaptic metaplasticity. Metaplasticity is a higher-order form of plasticity and is manifest as a change in the ability to induce subsequent synaptic plasticity that is the ability of synapses to change as circumstances require.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0030337	biolink:NamedThing	DNA polymerase processivity factor activity	An enzyme regulator activity that increases the processivity of polymerization by DNA polymerase, by allowing the polymerase to move rapidly along DNA while remaining topologically bound to it.	tmpzr1t_l9r_go_relaxed.owl	sliding clamp|processivity clamp													molecular_function											owl:Class	
GO:1904594	biolink:NamedThing	regulation of termination of RNA polymerase II transcription	Any process that modulates the frequency, rate or extent of termination of RNA polymerase II transcription.	tmpzr1t_l9r_go_relaxed.owl	regulation of RNA polymerase II transcription termination factor activity|regulation of transcription termination from Pol II promoter|regulation of RNA 3'-end formation by RNA polymerase II|regulation of transcription termination from RNA polymerase II promoter|regulation of RNA polymerase II transcription termination							al	2015-08-25T08:56:06Z					biological_process											owl:Class	
GO:1901417	biolink:NamedThing	negative regulation of response to ethanol	Any process that stops, prevents or reduces the frequency, rate or extent of response to ethanol.	tmpzr1t_l9r_go_relaxed.owl	downregulation of response to ethanol|down-regulation of response to ethanol|inhibition of response to ethanol|down regulation of response to ethanol							tt	2012-10-01T16:49:33Z					biological_process											owl:Class	
GO:0038087	biolink:NamedThing	VEGF-activated platelet-derived growth factor receptor-alpha signaling pathway	A series of molecular signals initiated by the binding of a vascular endothelial growth factor (VEGF) to an alpha-type platelet-derived growth factor receptor (PDGFR) on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.	tmpzr1t_l9r_go_relaxed.owl	VEGF-activated platelet-derived growth factor receptor-alpha signalling pathway|VEGF-activated PDGFRalpha signalling pathway|VEGF/PDGFRalpha signaling pathway|vascular endothelial growth factor-activated platelet-derived growth factor receptor-alpha signaling pathway|VEGF-A/PDGFRalpha signaling							bf	2012-02-01T03:08:13Z					biological_process											owl:Class	
GO:0070217	biolink:NamedThing	transcription factor TFIIIB complex assembly	The aggregation, arrangement and bonding together of a set of components to form a transcription factor TFIIIB complex.	tmpzr1t_l9r_go_relaxed.owl	TFIIIB assembly													biological_process											owl:Class	
GO:1902016	biolink:NamedThing	poly(glucopyranosyl N-acetylgalactosamine 1-phosphate) teichoic acid biosynthetic process	The chemical reactions and pathways resulting in the formation of poly(glucopyranosyl N-acetylgalactosamine 1-phosphate) teichoic acid.	tmpzr1t_l9r_go_relaxed.owl	poly(glucosyl N-acetylgalactosamine 1-phosphate) teichoic acid biosynthetic process|poly(glucosyl N-acetylgalactosamine 1-phosphate) teichoic acid biosynthesis|poly(glucopyranosyl N-acetylgalactosamine 1-phosphate) teichoic acid biosynthesis|poly(glucopyranosyl N-acetylgalactosamine 1-phosphate) teichoic acid anabolism|poly(glucopyranosyl N-acetylgalactosamine 1-phosphate) teichoic acid synthesis|poly(glucopyranosyl N-acetylgalactosamine 1-phosphate) teichoic acid formation							tb	2013-03-22T15:43:59Z					biological_process											owl:Class	
GO:1902015	biolink:NamedThing	poly(glucopyranosyl N-acetylgalactosamine 1-phosphate) teichoic acid metabolic process	The chemical reactions and pathways involving poly(glucopyranosyl N-acetylgalactosamine 1-phosphate) teichoic acid.	tmpzr1t_l9r_go_relaxed.owl	poly(glucosyl N-acetylgalactosamine 1-phosphate) teichoic acid metabolism|poly(glucopyranosyl N-acetylgalactosamine 1-phosphate) teichoic acid metabolism|poly(glucosyl N-acetylgalactosamine 1-phosphate) teichoic acid metabolic process							tb	2013-03-22T15:43:55Z					biological_process											owl:Class	
GO:0009777	biolink:NamedThing	photosynthetic phosphorylation	Any metabolic process in which photosynthetic organisms use light energy to convert ADP to ATP without the concomitant reduction of dioxygen (O2) to water that occurs in phosphorylation.	tmpzr1t_l9r_go_relaxed.owl	photosynthetic ATP synthesis													biological_process											owl:Class	
GO:0032349	biolink:NamedThing	positive regulation of aldosterone biosynthetic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of aldosterone.	tmpzr1t_l9r_go_relaxed.owl	stimulation of aldosterone biosynthetic process|upregulation of aldosterone biosynthetic process|activation of aldosterone biosynthetic process|up-regulation of aldosterone biosynthetic process|up regulation of aldosterone biosynthetic process													biological_process											owl:Class	
GO:0008013	biolink:NamedThing	beta-catenin binding	Binding to a catenin beta subunit.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0033862	biolink:NamedThing	UMP kinase activity	Catalysis of the reaction: ATP + UMP = ADP + UDP.	tmpzr1t_l9r_go_relaxed.owl	ATP:UMP phosphotransferase activity|uridine monophosphate kinase activity|SmbA|UMPK|PyrH|UMP-kinase activity				EC:2.7.4.22|RHEA:24400|MetaCyc:2.7.4.22-RXN									molecular_function											owl:Class	
GO:0009041	biolink:NamedThing	uridylate kinase activity	Catalysis of the reaction: ATP + (d)UMP = ADP + (d)UDP.	tmpzr1t_l9r_go_relaxed.owl					EC:2.7.4.22									molecular_function											owl:Class	
GO:0019728	biolink:NamedThing	peptidyl-allysine oxidation to 2-aminoadipic acid	The oxidation of allysine to 2-aminoadipic acid.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0370									biological_process											owl:Class	
GO:0007088	biolink:NamedThing	regulation of mitotic nuclear division	Any process that modulates the frequency, rate or extent of mitosis.	tmpzr1t_l9r_go_relaxed.owl	regulation of mitosis													biological_process											owl:Class	
GO:0047627	biolink:NamedThing	adenylylsulfatase activity	Catalysis of the reaction: 5'-adenylyl sulfate + H(2)O = AMP + 2 H(+) + sulfate.	tmpzr1t_l9r_go_relaxed.owl	adenylylsulphatase activity|adenosine 5-phosphosulfate sulfohydrolase activity|adenylylsulfate sulfohydrolase activity				MetaCyc:ADENYLYLSULFATASE-RXN|KEGG_REACTION:R00531|RHEA:17041|EC:3.6.2.1									molecular_function											owl:Class	
GO:1900219	biolink:NamedThing	positive regulation of apoptotic process involved in metanephric nephron tubule development	Any process that activates or increases the frequency, rate or extent of apoptotic process involved in metanephric nephron tubule development.	tmpzr1t_l9r_go_relaxed.owl	upregulation of type I programmed cell death of metanephric nephron tubule development|positive regulation of apoptotic process of metanephric nephron tubule development|positive regulation of apoptotic programmed cell death of metanephric nephron tubule development|up-regulation of apoptosis of metanephric nephron tubule development|up regulation of apoptotic cell death of metanephric nephron tubule development|upregulation of apoptotic programmed cell death of metanephric nephron tubule development|up regulation of apoptotic programmed cell death of metanephric nephron tubule development|up-regulation of apoptotic program of metanephric nephron tubule development|up-regulation of apoptotic cell death of metanephric nephron tubule development|up-regulation of apoptotic programmed cell death of metanephric nephron tubule development|activation of apoptotic program of metanephric nephron tubule development|up-regulation of apoptotic process involved in metanephric nephron tubule development|up regulation of programmed cell death by apoptosis of metanephric nephron tubule development|upregulation of apoptosis of metanephric nephron tubule development|upregulation of apoptotic process of metanephric nephron tubule development|up regulation of signaling (initiator) caspase activity of metanephric nephron tubule development|activation of apoptotic process of metanephric nephron tubule development|up-regulation of apoptotic process of metanephric nephron tubule development|up regulation of apoptotic process of metanephric nephron tubule development|up-regulation of type I programmed cell death of metanephric nephron tubule development|up regulation of apoptotic program of metanephric nephron tubule development|activation of apoptotic cell death of metanephric nephron tubule development|upregulation of programmed cell death by apoptosis of metanephric nephron tubule development|positive regulation of apoptotic program of metanephric nephron tubule development|activation of type I programmed cell death of metanephric nephron tubule development|up-regulation of programmed cell death by apoptosis of metanephric nephron tubule development|upregulation of apoptotic cell death of metanephric nephron tubule development|positive regulation of signaling (initiator) caspase activity of metanephric nephron tubule development|upregulation of signaling (initiator) caspase activity of metanephric nephron tubule development|activation of programmed cell death by apoptosis of metanephric nephron tubule development|activation of signaling (initiator) caspase activity of metanephric nephron tubule development|up regulation of apoptosis of metanephric nephron tubule development|upregulation of apoptotic process involved in metanephric nephron tubule development|positive regulation of type I programmed cell death of metanephric nephron tubule development|positive regulation of programmed cell death by apoptosis of metanephric nephron tubule development|activation of apoptotic programmed cell death of metanephric nephron tubule development|upregulation of apoptotic program of metanephric nephron tubule development|positive regulation of apoptotic cell death of metanephric nephron tubule development|up regulation of type I programmed cell death of metanephric nephron tubule development|activation of apoptosis of metanephric nephron tubule development|up regulation of apoptotic process involved in metanephric nephron tubule development|activation of apoptotic process involved in metanephric nephron tubule development|positive regulation of apoptosis of metanephric nephron tubule development|up-regulation of signaling (initiator) caspase activity of metanephric nephron tubule development							yaf	2012-03-22T10:54:09Z					biological_process											owl:Class	
GO:0019608	biolink:NamedThing	nicotine catabolic process	The chemical reactions and pathways resulting in the breakdown of nicotine, (S)(-)-3-(1-methyl-2-pyrrolidinyl)pyridine.	tmpzr1t_l9r_go_relaxed.owl	nicotine catabolism|nicotine breakdown|nicotine degradation				UM-BBD_pathwayID:nic|MetaCyc:P181-PWY									biological_process											owl:Class	
GO:0018933	biolink:NamedThing	nicotine metabolic process	The chemical reactions and pathways involving nicotine, (S)(-)-3-(1-methyl-2-pyrrolidinyl)pyridine.	tmpzr1t_l9r_go_relaxed.owl	nicotine metabolism													biological_process											owl:Class	
GO:0030249	biolink:NamedThing	guanylate cyclase regulator activity	Modulates the activity of guanylate cyclase.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0042933	biolink:NamedThing	chrysobactin transmembrane transporter activity	Enables the directed movement of the siderophore chrysobactin (alpha-N-(2,3-dihydroxybenzoyl)-D-lysyl-L-serine) from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	chrysobactin transporter activity													molecular_function											owl:Class	
GO:0050861	biolink:NamedThing	positive regulation of B cell receptor signaling pathway	Any process that activates or increases the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a B cell.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of B lymphocyte receptor signaling pathway|positive regulation of B-lymphocyte receptor signalling pathway|up-regulation of B cell receptor signaling pathway|positive regulation of B-cell receptor signaling pathway|positive regulation of B cell receptor signalling pathway|positive regulation of B-cell receptor signalling pathway|activation of B cell receptor signaling pathway|positive regulation of B lymphocyte receptor signalling pathway|positive regulation of B-lymphocyte receptor signaling pathway|upregulation of B cell receptor signaling pathway|up regulation of B cell receptor signaling pathway|stimulation of B cell receptor signaling pathway													biological_process											owl:Class	
GO:1901222	biolink:NamedThing	regulation of NIK/NF-kappaB signaling	Any process that modulates the frequency, rate or extent of NIK/NF-kappaB signaling.	tmpzr1t_l9r_go_relaxed.owl	NF-KB import into nucleus|NF-kappaB import into nucleus|regulation of non-canonical NF-KB signaling|regulation of p52-dependent NF-kappaB signaling|regulation of NIK/NF-kappaB cascade|regulation of noncanonical NF-kappaB signaling|regulation of NF-kappaB import into nucleus|regulation of noncanonical nuclear factor kappaB (NF-kappaB) pathway							hjd	2012-08-06T20:27:17Z			GO:0042345|GO:0042348		biological_process											owl:Class	
GO:0009201	biolink:NamedThing	ribonucleoside triphosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of a ribonucleoside triphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with triphosphate on the sugar.	tmpzr1t_l9r_go_relaxed.owl	ribonucleoside triphosphate biosynthesis|ribonucleoside triphosphate formation|ribonucleoside triphosphate anabolism|ribonucleoside triphosphate synthesis													biological_process											owl:Class	
GO:0043164	biolink:NamedThing	Gram-negative-bacterium-type cell wall biogenesis	A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cell wall of the type found in Gram-negative bacteria. The cell wall is the rigid or semi-rigid envelope lying outside the cell membrane.	tmpzr1t_l9r_go_relaxed.owl	1-2nm peptidoglycan-based cell wall biogenesis|cell wall formation|cell wall assembly|cell wall anabolism|cell wall synthesis|cell wall biosynthetic process													biological_process											owl:Class	
GO:0009330	biolink:NamedThing	DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) complex	Complex that possesses DNA topoisomerase II (double strand cut, ATP-hydrolyzing) activity.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0050897	biolink:NamedThing	cobalt ion binding	Binding to a cobalt ion (Co).	tmpzr1t_l9r_go_relaxed.owl	Co ion binding|cobalt binding													molecular_function											owl:Class	
GO:0003755	biolink:NamedThing	peptidyl-prolyl cis-trans isomerase activity	Catalysis of the reaction: peptidyl-proline (omega=180) = peptidyl-proline (omega=0).	tmpzr1t_l9r_go_relaxed.owl	parvulin|cis-trans proline isomerase activity|peptidylproline cis-trans-isomerase activity|peptidyl-prolyl isomerase B reaction|PPIase activity|cyclophilin activity|rotamase activity|juglone-sensitive peptidyl-prolyl cis-trans isomerase activity|immunophilin|peptidylprolyl isomerase activity|peptide bond isomerase activity|FK506-sensitive peptidyl-prolyl cis-trans isomerase|cyclophilin-type peptidyl-prolyl cis-trans isomerase activity|juglone-sensitive cis-trans proline isomerase activity|peptidylprolyl cis-trans isomerase activity				Reactome:R-HSA-2022073|RHEA:16237|Reactome:R-HSA-9626816|EC:5.2.1.8|MetaCyc:PEPTIDYLPROLYL-ISOMERASE-RXN							GO:0042028|GO:0004752		molecular_function											owl:Class	
GO:1904099	biolink:NamedThing	negative regulation of protein O-linked glycosylation	Any process that stops, prevents or reduces the frequency, rate or extent of protein O-linked glycosylation.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of protein amino acid O-linked glycosylation|inhibition of protein amino acid O-linked glycosylation|down regulation of protein amino acid O-linked glycosylation|inhibition of protein O-linked glycosylation|down-regulation of protein amino acid O-linked glycosylation|down regulation of protein O-linked glycosylation|downregulation of protein amino acid O-linked glycosylation|downregulation of protein O-linked glycosylation|down-regulation of protein O-linked glycosylation							krc	2015-03-27T16:10:04Z					biological_process											owl:Class	
GO:1904098	biolink:NamedThing	regulation of protein O-linked glycosylation	Any process that modulates the frequency, rate or extent of protein O-linked glycosylation.	tmpzr1t_l9r_go_relaxed.owl	regulation of protein amino acid O-linked glycosylation							krc	2015-03-27T16:09:58Z					biological_process											owl:Class	
GO:0060161	biolink:NamedThing	positive regulation of dopamine receptor signaling pathway	Any process that activates or increases the frequency, rate or extent of the dopamine receptor protein signaling pathway. A dopamine receptor signaling pathway is the series of molecular signals generated as a consequence of a dopamine receptor binding to one of its physiological ligands.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of dopamine receptor signalling pathway													biological_process											owl:Class	
GO:1904774	biolink:NamedThing	negative regulation of ubiquinone biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of ubiquinone biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	downregulation of coenzyme Q6 biosynthesis|inhibition of coenzyme Q10 biosynthetic process|negative regulation of coenzyme Q10 biosynthesis|inhibition of ubiquinone biosynthetic process|down regulation of coenzyme Q biosynthetic process|down-regulation of coenzyme Q8 biosynthetic process|negative regulation of ubiquinone anabolism|downregulation of coenzyme Q6 biosynthetic process|down regulation of coenzyme Q10 biosynthesis|inhibition of coenzyme Q biosynthesis|down-regulation of coenzyme Q10 biosynthesis|downregulation of coenzyme Q biosynthetic process|down regulation of ubiquinone biosynthetic process|downregulation of coenzyme Q10 biosynthesis|downregulation of ubiquinone biosynthesis|downregulation of coenzyme Q10 biosynthetic process|down regulation of ubiquinone biosynthesis|down-regulation of coenzyme Q8 biosynthesis|negative regulation of ubiquinone biosynthesis|inhibition of ubiquinone formation|down-regulation of coenzyme Q biosynthetic process|negative regulation of coenzyme Q9 biosynthetic process|downregulation of ubiquinone anabolism|negative regulation of ubiquinone synthesis|inhibition of coenzyme Q10 biosynthesis|down regulation of coenzyme Q9 biosynthesis|negative regulation of coenzyme Q6 biosynthetic process|inhibition of coenzyme Q9 biosynthesis|down-regulation of ubiquinone biosynthesis|downregulation of ubiquinone biosynthetic process|down-regulation of coenzyme Q10 biosynthetic process|down regulation of coenzyme Q8 biosynthesis|down-regulation of coenzyme Q biosynthesis|down regulation of coenzyme Q10 biosynthetic process|down-regulation of ubiquinone formation|inhibition of ubiquinone biosynthesis|down regulation of ubiquinone formation|negative regulation of coenzyme Q8 biosynthesis|down-regulation of ubiquinone biosynthetic process|negative regulation of coenzyme Q10 biosynthetic process|downregulation of ubiquinone formation|inhibition of coenzyme Q biosynthetic process|downregulation of coenzyme Q8 biosynthetic process|down regulation of coenzyme Q biosynthesis|inhibition of coenzyme Q8 biosynthetic process|down regulation of coenzyme Q6 biosynthesis|down regulation of coenzyme Q9 biosynthetic process|down-regulation of coenzyme Q9 biosynthesis|inhibition of coenzyme Q6 biosynthetic process|inhibition of ubiquinone anabolism|downregulation of coenzyme Q9 biosynthetic process|negative regulation of coenzyme Q biosynthesis|down regulation of ubiquinone anabolism|negative regulation of coenzyme Q6 biosynthesis|down-regulation of coenzyme Q6 biosynthesis|downregulation of coenzyme Q biosynthesis|down regulation of coenzyme Q8 biosynthetic process|negative regulation of coenzyme Q8 biosynthetic process|down regulation of coenzyme Q6 biosynthetic process|negative regulation of ubiquinone formation|down-regulation of ubiquinone synthesis|inhibition of ubiquinone synthesis|down-regulation of ubiquinone anabolism|downregulation of ubiquinone synthesis|inhibition of coenzyme Q9 biosynthetic process|downregulation of coenzyme Q8 biosynthesis|negative regulation of coenzyme Q9 biosynthesis|down-regulation of coenzyme Q6 biosynthetic process|inhibition of coenzyme Q8 biosynthesis|down regulation of ubiquinone synthesis|negative regulation of coenzyme Q biosynthetic process|downregulation of coenzyme Q9 biosynthesis|inhibition of coenzyme Q6 biosynthesis|down-regulation of coenzyme Q9 biosynthetic process							sl	2015-10-28T21:21:20Z					biological_process											owl:Class	
GO:0099020	biolink:NamedThing	perinuclear endoplasmic reticulum lumen	The volume enclosed by the membranes of the perinuclear endoplasmic reticulum.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0005788	biolink:NamedThing	endoplasmic reticulum lumen	The volume enclosed by the membranes of the endoplasmic reticulum.	tmpzr1t_l9r_go_relaxed.owl	cisternal lumen|endoplasmic reticulum cisterna|ER lumen|ER cisterna											GO:0016022		cellular_component											owl:Class	
GO:0097088	biolink:NamedThing	interleukin-17F production	The appearance of interleukin-17F due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	tmpzr1t_l9r_go_relaxed.owl	IL-17F production							pr	2011-06-23T11:32:59Z					biological_process											owl:Class	
GO:0010862	biolink:NamedThing	positive regulation of pathway-restricted SMAD protein phosphorylation	Any process that increases the rate, frequency or extent of pathway-restricted SMAD protein phosphorylation. Pathway-restricted SMAD proteins and common-partner SMAD proteins are involved in the transforming growth factor beta receptor signaling pathways.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0080054	biolink:NamedThing	low-affinity nitrate transmembrane transporter activity	Enables the transfer of nitrate ions (NO3-) from one side of a membrane to the other. In low-affinity transport the transporter is able to bind the solute only if it is present at very high concentrations.	tmpzr1t_l9r_go_relaxed.owl	low affinity nitrate transmembrane transporter activity													molecular_function											owl:Class	
GO:0060314	biolink:NamedThing	regulation of ryanodine-sensitive calcium-release channel activity	Any process that modulates the activity of a ryanodine-sensitive calcium-release channel. The ryanodine-sensitive calcium-release channel catalyzes the transmembrane transfer of a calcium ion by a channel that opens when a ryanodine class ligand has been bound by the channel complex or one of its constituent parts.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0019525	biolink:NamedThing	keto-D-gluconate metabolic process	The chemical reactions and pathways involving keto-D-gluconate, the anion of keto-D-gluconic acid, an aldonic acid derived from glucose.	tmpzr1t_l9r_go_relaxed.owl	keto-D-gluconate metabolism													biological_process											owl:Class	
GO:0071455	biolink:NamedThing	cellular response to hyperoxia	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating increased oxygen tension.	tmpzr1t_l9r_go_relaxed.owl	cellular response to increased oxygen tension|cellular response to hyperoxic stress							mah	2009-12-16T04:44:41Z					biological_process											owl:Class	
GO:0052546	biolink:NamedThing	cell wall pectin metabolic process	The chemical reactions and pathways involving pectin, a polymer containing a backbone of alpha-1,4-linked D-galacturonic acid residues, as part of the organization and biogenesis of the cell wall.	tmpzr1t_l9r_go_relaxed.owl	pectin metabolism during cell wall biogenesis|cellulose and pectin-containing cell wall pectin metabolic process|plant-type cell wall pectin metabolic process|cell wall pectin metabolism													biological_process											owl:Class	
GO:0034711	biolink:NamedThing	inhibin binding	Binding to an inhibin monomer, any of the polypeptides that combine to form activin and inhibin dimers.	tmpzr1t_l9r_go_relaxed.owl	inhibin alpha binding|inhibin beta-B binding|inhibin monomer binding|inhibin beta-A binding											GO:0048187|GO:0034712|GO:0048186		molecular_function											owl:Class	
GO:0099188	biolink:NamedThing	postsynaptic cytoskeleton organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising cytoskeletal filaments and their associated proteins in the postsynaptic cytoskeleton.	tmpzr1t_l9r_go_relaxed.owl								dos	2017-12-20T15:06:57Z					biological_process											owl:Class	
GO:0060025	biolink:NamedThing	regulation of synaptic activity	Any process that modulates the frequency, rate or extent of synaptic activity, the controlled release of neurotransmitters into the synaptic cleft and their subsequent detection by a postsynaptic cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0042305	biolink:NamedThing	specification of segmental identity, mandibular segment	The specification of the characteristic structures of the mandibular segment following establishment of segment boundaries. Identity is considered to be the aggregate of characteristics by which a structure is recognized.	tmpzr1t_l9r_go_relaxed.owl						See also the fly_anatomy.ontology term 'mandibular segment ; FBbt:00000012'.								biological_process											owl:Class	
GO:0004138	biolink:NamedThing	deoxyguanosine kinase activity	Catalysis of the reaction: 2'-deoxyguanosine + ATP = ADP + dGMP + 2 H(+).	tmpzr1t_l9r_go_relaxed.owl	deoxyguanosine kinase (phosphorylating)|2'-deoxyguanosine kinase activity|(dihydroxypropoxymethyl)guanine kinase activity|ATP:deoxyguanosine 5'-phosphotransferase activity|NTP-deoxyguanosine 5'-phosphotransferase activity				KEGG_REACTION:R01967|EC:2.7.1.113|RHEA:19201|MetaCyc:DEOXYGUANOSINE-KINASE-RXN									molecular_function											owl:Class	
GO:0019136	biolink:NamedThing	deoxynucleoside kinase activity	Catalysis of the reaction: ATP + 2'-deoxynucleoside = ADP + 2'-deoxynucleoside 5'-phosphate.	tmpzr1t_l9r_go_relaxed.owl	ATP:deoxynucleoside 5'-phosphotransferase activity|multifunctional deoxynucleoside kinase activity|D. melanogaster deoxynucleoside kinase activity|ms-dNK|multispecific deoxynucleoside kinase activity|Ms-dNK activity|Dm-dNK|multisubstrate deoxyribonucleoside kinase activity				MetaCyc:2.7.1.145-RXN|RHEA:12140|EC:2.7.1.145									molecular_function											owl:Class	
GO:1905841	biolink:NamedThing	response to oxidopamine	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxidopamine stimulus.	tmpzr1t_l9r_go_relaxed.owl								pr	2017-01-19T09:49:03Z					biological_process											owl:Class	
GO:0072342	biolink:NamedThing	response to anion stress	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of anion stress, an increase or decrease in the concentration of negatively charged ions in the environment.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-11-05T02:25:28Z					biological_process											owl:Class	
GO:0047009	biolink:NamedThing	3-alpha-hydroxy-5-beta-androstane-17-one 3-alpha-dehydrogenase activity	Catalysis of the reaction: NAD+ + 3-alpha-hydroxy-5-beta-androstane-17-one = NADH + H+ + 5-beta-androstane-3,17-dione.	tmpzr1t_l9r_go_relaxed.owl	3alpha-hydroxy-5beta-steroid:NAD+ 3-oxidoreductase activity|etiocholanolone 3-alpha-dehydrogenase activity|3alpha-hydroxy-5beta-steroid dehydrogenase activity|etiocholanolone 3alpha-dehydrogenase activity|3alpha-hydroxy-5beta-androstane-17-one 3alpha-dehydrogenase activity				EC:1.1.1.152|MetaCyc:1.1.1.152-RXN|RHEA:10356									molecular_function											owl:Class	
GO:0019578	biolink:NamedThing	aldaric acid biosynthetic process	The chemical reactions and pathways resulting in the formation of aldaric acid, any dicarboxylic acid formed by oxidation of by the terminal groups of an aldose to carboxyl group.	tmpzr1t_l9r_go_relaxed.owl	aldaric acid formation|aldaric acid biosynthesis|aldaric acid anabolism|aldaric acid synthesis													biological_process											owl:Class	
GO:0042823	biolink:NamedThing	pyridoxal phosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of pyridoxal phosphate, pyridoxal phosphorylated at the hydroxymethyl group of C-5, the active form of vitamin B6.	tmpzr1t_l9r_go_relaxed.owl	active vitamin B6 biosynthesis|pyridoxal phosphate formation|pyridoxal phosphate biosynthesis|active vitamin B6 biosynthetic process|pyridoxal phosphate anabolism|pyridoxal phosphate synthesis				MetaCyc:PWY0-845									biological_process											owl:Class	
GO:1902199	biolink:NamedThing	3-methylbut-2-enoyl-CoA(4-) catabolic process	The chemical reactions and pathways resulting in the breakdown of 3-methylbut-2-enoyl-CoA(4-).	tmpzr1t_l9r_go_relaxed.owl	3-methylbut-2-enoyl-CoA(4-) catabolism|3-methylbut-2-enoyl-CoA(4-) degradation|3-methylbut-2-enoyl-CoA(4-) breakdown							ms	2013-06-06T09:56:16Z					biological_process											owl:Class	
GO:0032571	biolink:NamedThing	response to vitamin K	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin K stimulus.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0036046	biolink:NamedThing	protein demalonylation	The removal of a malonyl group (CO-CH2-CO), from an amino acid residue within a protein or peptide.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-12-12T09:38:26Z					biological_process											owl:Class	
GO:2001178	biolink:NamedThing	positive regulation of mediator complex assembly	Any process that activates or increases the frequency, rate or extent of mediator complex assembly.	tmpzr1t_l9r_go_relaxed.owl								yaf	2011-11-02T11:22:27Z					biological_process											owl:Class	
GO:0060195	biolink:NamedThing	negative regulation of antisense RNA transcription	Any process that decreases the frequency, rate or extent of the synthesis of antisense RNA, an RNA molecule complementary in sequence to another RNA or DNA molecule, which, by binding the latter, acts to inhibit its function and/or completion of synthesis, on a template of DNA.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0060194	biolink:NamedThing	regulation of antisense RNA transcription	Any process that modulates the frequency, rate or extent of the synthesis of antisense RNA, an RNA molecule complementary in sequence to another RNA or DNA molecule, which, by binding the latter, acts to inhibit its function and/or completion of synthesis, on a template of DNA.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0009778	biolink:NamedThing	cyclic photosynthetic phosphorylation	A photosynthetic phosphorylation process in which ATP synthesis is driven by a proton gradient generated across the thylakoid membrane. Involves only photosystem I.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0035839	biolink:NamedThing	non-growing cell tip	A cell tip at which no growth takes place. For example, in fission yeast the cell end newly formed by cell division does not grow immediately upon its formation, and lacks actin cytoskeletal structures.	tmpzr1t_l9r_go_relaxed.owl	non-growing cell end|new cell end							bf	2011-05-06T01:32:21Z					cellular_component											owl:Class	
GO:2000693	biolink:NamedThing	positive regulation of seed maturation	Any process that activates or increases the frequency, rate or extent of seed maturation.	tmpzr1t_l9r_go_relaxed.owl								dhl	2011-05-13T06:41:46Z					biological_process											owl:Class	
GO:0086085	biolink:NamedThing	cell adhesive protein binding involved in SA cardiac muscle cell-atrial cardiac muscle cell communication	Binding to a protein or protein complex that results in the connection of an SA cardiomyocyte with an atrial cardiomyocyte and contributes to the communication between the two cells.	tmpzr1t_l9r_go_relaxed.owl	cell adhesive protein binding involved in SA cardiomyocyte-atrial cardiomyocyte communication							dph	2011-11-22T11:15:07Z					molecular_function											owl:Class	
GO:0002827	biolink:NamedThing	positive regulation of T-helper 1 type immune response	Any process that activates or increases the frequency, rate, or extent of a T-helper 1 type immune response.	tmpzr1t_l9r_go_relaxed.owl	activation of T-helper 1 type immune response|stimulation of T-helper 1 type immune response|up regulation of T-helper 1 type immune response|upregulation of T-helper 1 type immune response|up-regulation of T-helper 1 type immune response													biological_process											owl:Class	
GO:0046680	biolink:NamedThing	response to DDT	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a DDT stimulus. DDT, dichlorodiphenyltrichloroethane, is a chlorinated hydrocarbon pesticide moderately toxic to humans and other animals.	tmpzr1t_l9r_go_relaxed.owl	DDT susceptibility/resistance|DDT resistance													biological_process											owl:Class	
GO:0140629	biolink:NamedThing	small conductance calcium-activated potassium channel inhibitor activity	Binds to and stops, prevents, or reduces the activity of a small conductance calcium-activated potassium channel.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/21175						pg	2021-03-25T09:53:57Z					molecular_function											owl:Class	
GO:0019870	biolink:NamedThing	potassium channel inhibitor activity	Binds to and stops, prevents, or reduces the activity of a potassium channel.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0044079	biolink:NamedThing	modulation by symbiont of host neurotransmitter secretion	Any process in which a symbiont organism modulates the frequency, rate or extent of the regulated release of a neurotransmitter from a cell in its host organism.	tmpzr1t_l9r_go_relaxed.owl	modulation of host neurotransmitter secretion by symbiont|modification by symbiont of host neurotransmitter secretion|regulation by symbiont of host neurotransmitter secretion													biological_process											owl:Class	
GO:0047158	biolink:NamedThing	sinapoylglucose-sinapoylglucose O-sinapoyltransferase activity	Catalysis of the reaction: 2 1-O-sinapoyl-beta-D-glucose = 1,2-di-O-sinapoyl-beta-D-glucose + D-glucose.	tmpzr1t_l9r_go_relaxed.owl	1-(hydroxycinnamoyl)-glucose:1-(hydroxycinnamoyl)-glucose hydroxycinnamoyltransferase activity|1-O-(4-hydroxy-3,5-dimethoxycinnamoyl)-beta-D-glucoside:1-O-(4-hydroxy-3,5-dimethoxycinnamoyl-beta-D-glucoside 1-O-sinapoyltransferase activity|hydroxycinnamoylglucose-hydroxycinnamoylglucose hydroxycinnamoyltransferase activity				EC:2.3.1.103|RHEA:22664|MetaCyc:2.3.1.103-RXN|KEGG_REACTION:R00063									molecular_function											owl:Class	
GO:0016753	biolink:NamedThing	O-sinapoyltransferase activity	Catalysis of the transfer of a sinapoyl group to an oxygen atom on the acceptor molecule.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0060917	biolink:NamedThing	regulation of (1->6)-beta-D-glucan biosynthetic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of (1->6)-beta-D-glucans.	tmpzr1t_l9r_go_relaxed.owl	regulation of 1,6-beta-glucan biosynthetic process							dph	2009-09-18T02:15:01Z					biological_process											owl:Class	
GO:0035597	biolink:NamedThing	N6-isopentenyladenosine methylthiotransferase activity	Catalysis of the methylthiolation (-SCH3 addition) at the C2 of the adenosine ring of N6-isopentenyladenosine (i6A) in tRNA, to form 2-methylthio-N6-isopentenyladenosine (ms2i6A).	tmpzr1t_l9r_go_relaxed.owl	i6A methylthiotransferase activity							bf	2010-11-12T01:26:58Z					molecular_function											owl:Class	
GO:0072491	biolink:NamedThing	toluene-containing compound catabolic process	The chemical reactions and pathways resulting in the breakdown of toluene, methylbenzene (formula C7H8), or any of its derivatives.	tmpzr1t_l9r_go_relaxed.owl	toluene-containing compound catabolism|toluene-containing compound breakdown|toluene and derivative catabolic process|toluene-containing compound degradation							mah	2010-12-14T03:51:03Z					biological_process											owl:Class	
GO:0030370	biolink:NamedThing	intercellular adhesion molecule-3 receptor binding	Binding to a receptor for intercellular adhesion molecule-3 (ICAM-3), such as DC-SIGN and LFA-1.	tmpzr1t_l9r_go_relaxed.owl	intercellular adhesion molecule-3 receptor ligand|ICAM-3 receptor binding|ICAM-3 receptor ligand													molecular_function											owl:Class	
GO:0015345	biolink:NamedThing	ferric enterobactin:proton symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ferric enterobactin(out) + H+(out) = ferric enterobactin(in) + H+(in).	tmpzr1t_l9r_go_relaxed.owl	ferric enterobactin:hydrogen symporter activity|ferric-enterobactin:proton symporter activity													molecular_function											owl:Class	
GO:0048633	biolink:NamedThing	positive regulation of skeletal muscle tissue growth	Any process that activates, maintains or increases the rate of skeletal muscle growth.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of skeletal muscle growth|stimulation of skeletal muscle growth|up regulation of skeletal muscle growth|activation of skeletal muscle growth|upregulation of skeletal muscle growth													biological_process											owl:Class	
GO:1905596	biolink:NamedThing	negative regulation of low-density lipoprotein particle receptor binding	Any process that stops, prevents or reduces the frequency, rate or extent of low-density lipoprotein particle receptor binding.	tmpzr1t_l9r_go_relaxed.owl	down regulation of low-density lipoprotein particle receptor binding|inhibition of low-density lipoprotein receptor binding|inhibition of low-density lipoprotein particle receptor binding|down-regulation of low-density lipoprotein receptor binding|down regulation of LDL receptor binding|down regulation of low-density lipoprotein receptor binding|down-regulation of LDL receptor binding|downregulation of LDL receptor binding|negative regulation of low-density lipoprotein receptor binding|down-regulation of low-density lipoprotein particle receptor binding|downregulation of low-density lipoprotein particle receptor binding|negative regulation of LDL receptor binding|inhibition of LDL receptor binding|downregulation of low-density lipoprotein receptor binding							nc	2016-10-26T10:57:31Z					biological_process											owl:Class	
GO:1905302	biolink:NamedThing	negative regulation of macropinocytosis	Any process that stops, prevents or reduces the frequency, rate or extent of macropinocytosis.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of macropinocytosis|inhibition of macropinocytosis|downregulation of macropinocytosis|down regulation of macropinocytosis							pad	2016-07-04T14:16:41Z					biological_process											owl:Class	
GO:1905228	biolink:NamedThing	positive regulation of adhesion of symbiont to host epithelial cell	Any process that activates or increases the frequency, rate or extent of adhesion of symbiont to host epithelial cell.	tmpzr1t_l9r_go_relaxed.owl	upregulation of adhesion of symbiont to host epithelial cell|activation of adhesion of symbiont to host epithelial cell|up regulation of adhesion of symbiont to host epithelial cell|up-regulation of adhesion of symbiont to host epithelial cell							pga	2016-06-07T13:15:24Z					biological_process											owl:Class	
GO:0062022	biolink:NamedThing	mitotic cohesin ssDNA (lagging strand) loading	The ATP-dependent protein localization to chromatin by which a cohesin ring complex is topologically linked to ssDNA (lagging strand) which is already linked to a dsDNA (leading strand) molecule as part of the mitotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl	second-DNA capture							dph	2018-04-06T13:06:36Z					biological_process											owl:Class	
GO:0010801	biolink:NamedThing	negative regulation of peptidyl-threonine phosphorylation	Any process that decreases the frequency, rate or extent of peptidyl-threonine phosphorylation. Peptidyl-threonine phosphorylation is the phosphorylation of peptidyl-threonine to form peptidyl-O-phospho-L-threonine.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0047942	biolink:NamedThing	glutamate-ethylamine ligase activity	Catalysis of the reaction: L-glutamate + ATP + ethylamine = N(5)-ethyl-L-glutamine + ADP + 2 H(+) + phosphate.	tmpzr1t_l9r_go_relaxed.owl	N5-ethylglutamine synthetase activity|N(5)-ethyl-L-glutamine synthetase activity|theanine synthetase activity|L-glutamate:ethylamine ligase (ADP-forming)|N5-ethyl-L-glutamine synthetase activity				KEGG_REACTION:R02929|MetaCyc:GLUTAMATE--ETHYLAMINE-LIGASE-RXN|RHEA:20525|EC:6.3.1.6									molecular_function											owl:Class	
GO:0031302	biolink:NamedThing	intrinsic component of endosome membrane	The component of the endosome membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.	tmpzr1t_l9r_go_relaxed.owl	intrinsic to endosome membrane													cellular_component											owl:Class	
GO:0048662	biolink:NamedThing	negative regulation of smooth muscle cell proliferation	Any process that stops, prevents or reduces the rate or extent of smooth muscle cell proliferation.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of SMC proliferation|down regulation of smooth muscle cell proliferation|downregulation of smooth muscle cell proliferation|inhibition of smooth muscle cell proliferation|down-regulation of smooth muscle cell proliferation													biological_process											owl:Class	
GO:0102871	biolink:NamedThing	1-16:0-2-18:1-phosphatidylcholine desaturase activity	Catalysis of the reaction: 1-16:0-2-18:1-phosphatidylcholine + O2 + a reduced electron acceptor <=> 1-palmitoyl-2-linoleoyl-phosphatidylcholine + 2 H2O + an oxidized electron acceptor.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-8360|EC:1.14.19.22									molecular_function											owl:Class	
GO:0021653	biolink:NamedThing	rhombomere 1 structural organization	The process that contributes to creating the structural organization of rhombomere 1. This process pertains to the physical shaping of a rudimentary structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.	tmpzr1t_l9r_go_relaxed.owl	rhombomere 1 structural organisation													biological_process											owl:Class	
GO:0051678	biolink:NamedThing	pullulan catabolic process	The chemical reactions and pathways resulting in the breakdown of pullulan, a neutral linear polysaccharide composed of repeating units of maltotriose joined by alpha-(1,6)-linkages.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0047931	biolink:NamedThing	glucosamine kinase activity	Catalysis of the reaction: ATP + D-glucosamine = ADP + D-glucosamine phosphate.	tmpzr1t_l9r_go_relaxed.owl	glucosamine kinase (phosphorylating)|ATP:D-glucosamine phosphotransferase activity|aminodeoxyglucose kinase activity|ATP:2-amino-2-deoxy-D-glucose-6-phosphotransferase activity				RHEA:10948|MetaCyc:GLUCOSAMINE-KINASE-RXN|EC:2.7.1.8									molecular_function											owl:Class	
GO:0106379	biolink:NamedThing	8-oxo-(d)RTP hydrolase activity	Catalysis of the reaction: 8-oxo-(d)RTP + H20 = 8-oxo-(d)RMP + diphosphate + H+.	tmpzr1t_l9r_go_relaxed.owl								hjd	2021-05-26T14:36:55Z					molecular_function											owl:Class	
GO:0035179	biolink:NamedThing	larval turning behavior	Fine-tuning the spatial position of a larva in response to variability in their environment. For example, reorientation of a larva in the direction of a food source.	tmpzr1t_l9r_go_relaxed.owl	larval turning behaviour													biological_process											owl:Class	
GO:0060761	biolink:NamedThing	negative regulation of response to cytokine stimulus	Any process that decreases the rate, frequency, or extent of a response to cytokine stimulus.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-06-22T02:59:57Z					biological_process											owl:Class	
GO:0032664	biolink:NamedThing	regulation of interleukin-20 production	Any process that modulates the frequency, rate, or extent of interleukin-20 production.	tmpzr1t_l9r_go_relaxed.owl	regulation of interleukin-20 biosynthetic process|regulation of IL-20 production											GO:0045387		biological_process											owl:Class	
GO:1990184	biolink:NamedThing	amino acid transport complex	A heteromeric protein complex consisting of a multi-transmembrane spanning subunit (the light chain) and a type II glycoprotein subunit (the heavy chain) that functions to transport amino acids across a plasma membrane.	tmpzr1t_l9r_go_relaxed.owl								jl	2013-09-11T15:02:16Z					cellular_component											owl:Class	
GO:1902573	biolink:NamedThing	positive regulation of serine-type peptidase activity	Any process that activates or increases the frequency, rate or extent of serine-type peptidase activity.	tmpzr1t_l9r_go_relaxed.owl	upregulation of serine-type peptidase activity|up-regulation of serine protease activity|activation of serine protease activity|activation of serine-type peptidase activity|up-regulation of serine-type peptidase activity|up regulation of serine protease activity|up regulation of serine-type peptidase activity|positive regulation of serine protease activity|upregulation of serine protease activity							krc	2013-12-10T18:17:16Z					biological_process											owl:Class	
GO:0031932	biolink:NamedThing	TORC2 complex	A protein complex that contains at least TOR (target of rapamycin) and Rictor (rapamycin-insensitive companion of TOR), or orthologs of, in complex with other signaling components. Mediates the phosphorylation and activation of PKB (also called AKT). In Saccharomyces, the complex contains Avo1p, Avo2p, Tsc11p, Lst8p, Bit61p, Slm1p, Slm2p, and Tor2p.	tmpzr1t_l9r_go_relaxed.owl	rapamycin and nutrient-insensitive TOR complex|TORC2|TORC 2 complex|mTORC2|TOR complex 2				Wikipedia:MTORC1									cellular_component											owl:Class	
GO:0038201	biolink:NamedThing	TOR complex	A protein complex that contains at least TOR (target of rapamycin) in complex with other signaling components. Mediates the phosphorylation and activation of downstream signaling components including PKB (AKT) or S6K.	tmpzr1t_l9r_go_relaxed.owl	TOR signaling complex|target of rapamycin complex|mTOR complex							bf	2013-12-09T14:38:09Z					cellular_component											owl:Class	
GO:0016157	biolink:NamedThing	sucrose synthase activity	Catalysis of the reaction: UDP-glucose + D-fructose = UDP + sucrose.	tmpzr1t_l9r_go_relaxed.owl	sucrose-UDP glucosyltransferase activity|sucrose synthetase activity|uridine diphosphoglucose-fructose glucosyltransferase activity|sucrose-uridine diphosphate glucosyltransferase activity|NDP-glucose:D-fructose 2-alpha-D-glucosyltransferase activity|UDP-glucose-fructose glucosyltransferase activity|UDPglucose-fructose glucosyltransferase activity				MetaCyc:SUCROSE-SYNTHASE-RXN|EC:2.4.1.13									molecular_function											owl:Class	
GO:1904602	biolink:NamedThing	serotonin-activated cation-selective channel complex	A protein complex which is capable of serotonin-activated cation-selective channel activity. Mainly found in pre- and postsynaptic membranes of the brain and gastrointestinal tract. Depending on its location it transports Ca2+, Mg2+, Na+ or K+. It is always a pentamer, containing at least the 5HT3A subunit forming 5HT3A homopentamers or 5HT3A/B heteropentamers. In human, 5HT3A/C, A/D and A/E heteropentamers also exist.	tmpzr1t_l9r_go_relaxed.owl	5HT3 receptor complex|serotonin receptor complex|5-HT3 receptor complex|5-hydroxytryptamine receptor 3 complex|5-HT-3 receptor complex	https://github.com/geneontology/go-ontology/issues/12942				An example of this is HTR3A in human (P46098) in PMID:16116092 (inferred from direct assay).		bhm	2015-08-26T13:19:49Z					cellular_component											owl:Class	
GO:0097272	biolink:NamedThing	ammonium homeostasis	Any biological process involved in the maintenance of an internal steady state of ammonium.	tmpzr1t_l9r_go_relaxed.owl	ammonia homeostasis							pr	2012-03-22T02:51:22Z					biological_process											owl:Class	
GO:1903248	biolink:NamedThing	regulation of citrulline biosynthetic process	Any process that modulates the frequency, rate or extent of citrulline biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of citrulline formation|regulation of citrulline synthesis|regulation of citrulline biosynthesis|regulation of citrulline anabolism							rl	2014-08-04T15:24:34Z					biological_process											owl:Class	
GO:0038032	biolink:NamedThing	termination of G protein-coupled receptor signaling pathway	The signaling process in which G protein-coupled receptor signaling is brought to an end. For example, through the action of GTPase-activating proteins (GAPs) that act to accelerate hydrolysis of GTP to GDP on G-alpha proteins, thereby terminating the transduced signal.	tmpzr1t_l9r_go_relaxed.owl	termination of G-protein coupled receptor signalling pathway|termination of GPCR signaling pathway|termination of G-protein coupled receptor signaling pathway							bf	2011-09-16T10:31:21Z					biological_process											owl:Class	
GO:1904519	biolink:NamedThing	protein localization to microtubule minus-end	A process in which a protein is transported to, or maintained in, a location at a microtubule minus-end.	tmpzr1t_l9r_go_relaxed.owl	protein localization in microtubule minus-end|protein localisation to microtubule minus-end|protein localisation in microtubule minus-end							mah	2015-07-29T14:46:11Z					biological_process											owl:Class	
GO:0102310	biolink:NamedThing	dTDP-(2R,6S)-6-hydroxy-2-methyl-3-oxo-3,6-dihydro-2H-pyran-4-olate 3-ketoreductase (dTDP-4-dehydro-2,6-dideoxy-alpha-D-allose-forming) activity	Catalysis of the reaction: dTDP-4-dehydro-2,6-dideoxy-alpha-D-allose + NAD(P) <=> dTDP-(2R,6S)-6-hydroxy-2-methyl-3-oxo-3,6-dihydro-2H-pyran-4-olate + 2 H+ + NAD(P)H.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-12940									molecular_function											owl:Class	
GO:2000919	biolink:NamedThing	negative regulation of glucuronoarabinoxylan catabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of glucuronoarabinoxylan catabolic process.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of glucuronoarabinoxylan catabolism							tt	2011-08-01T12:36:53Z					biological_process											owl:Class	
GO:0086052	biolink:NamedThing	membrane repolarization during SA node cell action potential	The process in which an SA node cardiac muscle cell membrane potential changes in the direction from the positive membrane potential at the peak of the action potential towards the negative resting potential.	tmpzr1t_l9r_go_relaxed.owl	membrane repolarization involved in regulation of SA node cardiac muscle cell action potential|membrane repolarization involved in regulation of SAN cardiac muscle cell action potential|membrane repolarization involved in regulation of sinus node cardiac muscle cell action potential|membrane repolarization involved in regulation of sinoatrial node cardiac muscle cell action potential							dph	2011-11-16T11:54:12Z					biological_process											owl:Class	
GO:0008938	biolink:NamedThing	nicotinate N-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine(1+) + nicotinate = N-methylnicotinate + S-adenosyl-L-homocysteine.	tmpzr1t_l9r_go_relaxed.owl	furanocoumarin 8-O-methyltransferase activity|S-adenosyl-L-methionine:nicotinate N-methyltransferase activity				EC:2.1.1.7|RHEA:20241|MetaCyc:NICOTINATE-N-METHYLTRANSFERASE-RXN|KEGG_REACTION:R01721									molecular_function											owl:Class	
GO:0050557	biolink:NamedThing	deacetylipecoside synthase activity	Catalysis of the reaction: deacetylipecoside + H(2)O = dopamine + secologanin.	tmpzr1t_l9r_go_relaxed.owl	deacetylipecoside dopamine-lyase activity|deacetylipecoside dopamine-lyase (secologanin-forming)				EC:4.3.3.4|MetaCyc:4.3.3.4-RXN|KEGG_REACTION:R05749|RHEA:12296									molecular_function											owl:Class	
GO:0010858	biolink:NamedThing	calcium-dependent protein kinase regulator activity	Modulates the activity of a calcium-dependent protein kinase, an enzyme which phosphorylates a protein in a calcium-dependent manner.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0042610	biolink:NamedThing	CD8 receptor binding	Binding to a CD8, a receptor found on the surface of thymocytes and cytotoxic and suppressor T-lymphocytes.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0102396	biolink:NamedThing	9-cis-10'-apo-beta-carotenal cleavage oxygenase activity	Catalysis of the reaction: 9-cis-10'-apo-beta-carotenal + 2 O2 <=> carlactone + (2E,4E,6E)-7-hydroxy-4-methylhepta-2,4,6-trienal.	tmpzr1t_l9r_go_relaxed.owl					EC:1.13.11.69|MetaCyc:RXN-13643|RHEA:34403									molecular_function											owl:Class	
GO:0062158	biolink:NamedThing	chloride:proton antiporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: chloride(out) + proton(in) = chloride(in) + proton(out).	tmpzr1t_l9r_go_relaxed.owl								dph	2019-09-24T19:26:32Z					molecular_function											owl:Class	
GO:0000752	biolink:NamedThing	agglutination involved in conjugation with cellular fusion	The aggregation or adhesion of compatible mating types via complementary cell-cell interactions during conjugation with cellular fusion of a unicellular organism. An example of this process is agglutination in Saccharomyces cerevisiae.	tmpzr1t_l9r_go_relaxed.owl	cell-cell adhesion during mating|agglutination|cell-cell adhesion during conjugation with cellular fusion											GO:0007334		biological_process											owl:Class	
GO:0060635	biolink:NamedThing	positive regulation of (1->3)-beta-D-glucan biosynthetic process	Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of 1,3-beta-D-glucan biosynthetic process							dph	2009-05-18T03:22:44Z					biological_process											owl:Class	
GO:1903221	biolink:NamedThing	regulation of mitotic recombination involved in replication fork processing	Any process that modulates the frequency, rate or extent of mitotic recombination involved in replication fork processing. Regulation of mitotic recombination contributes to replication fork processing by preventing recombination between inappropriate homologous sequences.	tmpzr1t_l9r_go_relaxed.owl	regulation of mitotic recombination involved in collapsed replication fork processing|prevention of genomic instability induced by DNA replication fork arrest|regulation of mitotic recombination involved in replication fork restart|regulation of mitotic recombination involved in replication restart|regulation of mitotic recombination involved in recovery from replication fork arrest|regulation of mitotic recombination involved in recovery from replication fork stalling							mah	2014-07-24T13:30:21Z					biological_process											owl:Class	
GO:0070485	biolink:NamedThing	dehydro-D-arabinono-1,4-lactone biosynthetic process	The chemical reactions and pathways resulting in the formation of dehydro-D-arabinono-1,4-lactone, the gamma-lactone (5R)-3,4-dihydroxy-5-(hydroxymethyl)furan-2(5H)-one.	tmpzr1t_l9r_go_relaxed.owl	dehydro-D-arabinono-1,4-lactone biosynthesis|dehydro-D-arabinono-1,4-lactone anabolism|dehydro-D-arabinono-1,4-lactone formation|dehydro-D-arabinono-1,4-lactone synthesis													biological_process											owl:Class	
GO:0071627	biolink:NamedThing	integral component of fungal-type vacuolar membrane	The component of the fungal-type vacuole membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.	tmpzr1t_l9r_go_relaxed.owl	integral to fungal-type vacuolar membrane							mah	2010-02-10T03:45:23Z					cellular_component											owl:Class	
GO:0030267	biolink:NamedThing	glyoxylate reductase (NADP+) activity	Catalysis of the reaction: glycolate + NADP+ = glyoxylate + NADPH + H+.	tmpzr1t_l9r_go_relaxed.owl	NADPH-glyoxylate reductase activity|glyoxylate reductase (NADP+)|glycolate:NADP+ oxidoreductase activity				Reactome:R-HSA-389826|Wikipedia:Glyoxylate_reductase_(NADP+)|RHEA:10992|MetaCyc:GLYOXYLATE-REDUCTASE-NADP+-RXN|EC:1.1.1.79									molecular_function											owl:Class	
GO:0106345	biolink:NamedThing	glyoxylate reductase activity	Catalysis of the reaction: glycolate + NAD(P)+ = glyoxylate + NAD(P)H.	tmpzr1t_l9r_go_relaxed.owl								hjd	2020-12-08T14:14:31Z					molecular_function											owl:Class	
GO:0071365	biolink:NamedThing	cellular response to auxin stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an auxin stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-12-11T03:10:22Z					biological_process											owl:Class	
GO:0018929	biolink:NamedThing	methyl fluoride metabolic process	The chemical reactions and pathways involving methyl fluoride, fluorine-substituted methane, a gaseous halogenated hydrocarbon that has been investigated as an inhibitor of methanotrophy and nitrification in soils.	tmpzr1t_l9r_go_relaxed.owl	methyl fluoride metabolism				UM-BBD_pathwayID:mf									biological_process											owl:Class	
GO:0010291	biolink:NamedThing	carotene beta-ring hydroxylase activity	Catalysis of the reaction: a carotene + a reduced electron acceptor + O2 = C3-hydroxylated carotene + an oxidized electron acceptor + H2O. This is a general reaction to represent the C3 hydroxylation of the beta ring of a carotene.	tmpzr1t_l9r_go_relaxed.owl	beta-carotene hydroxylase activity											GO:0042411		molecular_function											owl:Class	
GO:0140485	biolink:NamedThing	5-aminolevulinic acid transmembrane transporter activity	Enables the transfer of 5-aminolevulinic acid from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/19527			RHEA:64816			pg	2020-06-29T09:02:26Z					molecular_function											owl:Class	
GO:0102849	biolink:NamedThing	1-18:2-2-18:3-digalactosyldiacylglycerol desaturase activity	Catalysis of the reaction: 1-18:2-2-18:3-digalactosyldiacylglycerol + O2 + a reduced electron acceptor <=> 1-18:3-2-18:3-digalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor.	tmpzr1t_l9r_go_relaxed.owl					EC:1.14.19.35|MetaCyc:RXN-8314									molecular_function											owl:Class	
GO:0047962	biolink:NamedThing	glycine N-benzoyltransferase activity	Catalysis of the reaction: benzoyl-CoA + glycine = N-benzoylglycine + CoA + H(+).	tmpzr1t_l9r_go_relaxed.owl	benzoyl-CoA:glycine N-benzoyltransferase activity|benzoyl-CoA:glycine N-acyltransferase activity|benzoyl CoA-amino acid N-acyltransferase activity				EC:2.3.1.71|Reactome:R-HSA-159574|RHEA:18493|MetaCyc:GLYCINE-N-BENZOYLTRANSFERASE-RXN|Reactome:R-HSA-159566|KEGG_REACTION:R02452									molecular_function											owl:Class	
GO:0004766	biolink:NamedThing	spermidine synthase activity	Catalysis of the reaction: S-adenosylmethioninamine + putrescine = 5'-methylthioadenosine + spermidine.	tmpzr1t_l9r_go_relaxed.owl	aminopropyltransferase activity|spermidine synthetase activity|putrescine aminopropyltransferase activity|SpeE|S-adenosylmethioninamine:putrescine 3-aminopropyltransferase activity				RHEA:12721|Reactome:R-HSA-351215|MetaCyc:SPERMIDINESYN-RXN|EC:2.5.1.16									molecular_function											owl:Class	
GO:0034230	biolink:NamedThing	enkephalin processing	The formation of mature enkephalin, a pentapeptide hormone involved in regulating pain and nociception in the body by proteolytic processing of enkephalin propeptide.	tmpzr1t_l9r_go_relaxed.owl	peptide enkephalin processing|enkephalin formation|peptide enkephalin formation													biological_process											owl:Class	
GO:1990712	biolink:NamedThing	HFE-transferrin receptor complex	A protein complex containing at least HFE and a transferrin receptor (either TFR1/TFRC or TFR2), proposed to play a role in the sensing of transferrin-bound Fe (Fe2-Tf) on the plasma membrane to regulate hepcidin transcription.	tmpzr1t_l9r_go_relaxed.owl								pr	2015-03-26T13:03:27Z					cellular_component											owl:Class	
GO:0018493	biolink:NamedThing	formylmethanofuran dehydrogenase activity	Catalysis of the reaction: N-formylmethanofuran + A + H(2)O + H(+) = AH(2) + CO(2) + methanofuran.	tmpzr1t_l9r_go_relaxed.owl	formylmethanofuran:acceptor oxidoreductase activity|formylmethanofuran:(acceptor) oxidoreductase activity				RHEA:19841|UM-BBD_reactionID:r0345|KEGG_REACTION:R03015|EC:1.2.7.12|MetaCyc:FORMYLMETHANOFURAN-DEHYDROGENASE-RXN									molecular_function											owl:Class	
GO:0045958	biolink:NamedThing	positive regulation of complement activation, alternative pathway	Any process that activates or increases the frequency, rate or extent of complement activation by the alternative pathway.	tmpzr1t_l9r_go_relaxed.owl	stimulation of complement activation, alternative pathway|positive regulation of complement cascade, alternative pathway|up regulation of complement activation, alternative pathway|upregulation of complement activation, alternative pathway|activation of complement activation, alternative pathway|up-regulation of complement activation, alternative pathway													biological_process											owl:Class	
GO:0031213	biolink:NamedThing	RSF complex	An ISWI complex that contains an ATPase subunit of the ISWI family (SNF2H in mammals) and an RSF1 homolog. It mediates nucleosome deposition and generates regularly spaced nucleosome arrays. In mammals, RSF is involved in regulation of transcription from RNA polymerase II promoters).	tmpzr1t_l9r_go_relaxed.owl	remodeling and spacing factor complex													cellular_component											owl:Class	
GO:1903380	biolink:NamedThing	positive regulation of mitotic chromosome condensation	Any process that activates or increases the frequency, rate or extent of mitotic chromosome condensation.	tmpzr1t_l9r_go_relaxed.owl	up regulation of mitotic chromosome condensation|up-regulation of mitotic chromosome condensation|activation of mitotic chromosome condensation|upregulation of mitotic chromosome condensation							al	2014-08-26T13:57:29Z					biological_process											owl:Class	
GO:0022824	biolink:NamedThing	transmitter-gated ion channel activity	Enables the transmembrane transfer of an ion by a channel that opens when a specific neurotransmitter has been bound by the channel complex or one of its constituent parts.	tmpzr1t_l9r_go_relaxed.owl	ionotropic neurotransmitter receptor activity													molecular_function											owl:Class	
GO:0034704	biolink:NamedThing	calcium channel complex	An ion channel complex through which calcium ions pass.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0004145	biolink:NamedThing	diamine N-acetyltransferase activity	Catalysis of the reaction: acetyl-CoA + an alkane-alpha,omega-diamine = CoA + an N-acetyldiamine.	tmpzr1t_l9r_go_relaxed.owl	spermine N-acetyltransferase|acetyl-coenzyme A-1,4-diaminobutane N-acetyltransferase activity|spermine N(1)-acetyltransferase|putrescine (diamine)-acetylating enzyme activity|putrescine acetyltransferase activity|putrescine acetylase activity|diamine acetyltransferase activity|putrescine N-acetyltransferase activity|spermidine N1-acetyltransferase activity|spermidine N(1)-acetyltransferase activity|spermidine acetyltransferase activity|spermidine/spermine N1-acetyltransferase activity|acetyl-CoA:alkane-alpha,omega-diamine N-acetyltransferase activity|spermine acetyltransferase				Reactome:R-HSA-351208|RHEA:25181|MetaCyc:DIAMACTRANS-RXN|Reactome:R-HSA-351207|EC:2.3.1.57									molecular_function											owl:Class	
GO:0102201	biolink:NamedThing	(+)-2-epi-prezizaene synthase activity	Catalysis of the reaction: 2-cis,6-trans-farnesyl diphosphate <=> (+)-2-epi-prezizaene + diphosphoric acid.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-12117									molecular_function											owl:Class	
GO:0009159	biolink:NamedThing	deoxyribonucleoside monophosphate catabolic process	The chemical reactions and pathways resulting in the breakdown of a deoxyribonucleoside monophosphate, a compound consisting of a nucleobase linked to a deoxyribose sugar esterified with phosphate on the sugar.	tmpzr1t_l9r_go_relaxed.owl	deoxyribonucleoside monophosphate catabolism|deoxyribonucleoside monophosphate degradation|deoxyribonucleoside monophosphate breakdown													biological_process											owl:Class	
GO:0030761	biolink:NamedThing	8-hydroxyquercitin 8-O-methyltransferase activity	Catalysis of the reaction: 3,3',4',5,7,8-hexahydroxyflavone + S-adenosyl-L-methionine(1+) = 3,3',4',5,7-pentahydroxy-8-methoxyflavone + S-adenosyl-L-homocysteine + H(+).	tmpzr1t_l9r_go_relaxed.owl	8-hydroxyquercetin 8-O-methyltransferase activity|S-adenosyl-L-methionine:3,3',4',5,7,8-hexahydroxyflavone 8-O-methyltransferase activity|flavonol 8-O-methyltransferase activity|flavonol 8-methyltransferase activity				MetaCyc:2.1.1.88-RXN|RHEA:16593|EC:2.1.1.88|KEGG_REACTION:R04398									molecular_function											owl:Class	
GO:1901509	biolink:NamedThing	regulation of endothelial tube morphogenesis	Any process that modulates the frequency, rate or extent of endothelial tube morphogenesis.	tmpzr1t_l9r_go_relaxed.owl								dph	2012-10-17T14:30:40Z					biological_process											owl:Class	
GO:0120132	biolink:NamedThing	positive regulation of apoptotic process in bone marrow cell	Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process in the bone marrow.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of apoptosis in bone marrow|positive regulation of bone marrow cell apoptosis|upregulation of apoptosis in bone marrow|positive regulation of apoptosis in bone marrow|positive regulation of apoptotic process in bone marrow|up regulation of apoptosis in bone marrow|positive regulation of programmed cell death, bone marrow cells|positive regulation of programmed cell death of bone marrow cells by apoptosis|positive regulation of bone marrow cell programmed cell death by apoptosis|positive regulation of killing of bone marrow cells|activation of apoptosis in bone marrow							krc	2018-02-19T16:51:46Z					biological_process											owl:Class	
GO:0097079	biolink:NamedThing	selenite:proton symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: selenite(out) + H+(out) = selenite(in) + H+(in).	tmpzr1t_l9r_go_relaxed.owl	selenite:H+ symporter activity|selenite:hydrogen symporter activity							pr	2011-06-17T10:01:11Z					molecular_function											owl:Class	
GO:0044559	biolink:NamedThing	envenomation resulting in modulation of voltage-gated potassium channel activity in other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with a resultant change in the activity of a voltage-gated potassium channel in the bitten/stung organism.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-04-05T03:35:20Z					biological_process											owl:Class	
GO:0044819	biolink:NamedThing	mitotic G1/S transition checkpoint signaling	A cell cycle checkpoint that detects and negatively regulates progression from G1 to S phase as part of a mitotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl	mitotic G1/S transition checkpoint	https://github.com/geneontology/go-ontology/issues/20935						jl	2013-11-19T14:31:14Z					biological_process											owl:Class	
GO:0002669	biolink:NamedThing	positive regulation of T cell anergy	Any process that activates or increases the frequency, rate, or extent of T cell anergy.	tmpzr1t_l9r_go_relaxed.owl	activation of T cell anergy|upregulation of T cell anergy|positive regulation of T-cell anergy|up regulation of T cell anergy|up-regulation of T cell anergy|positive regulation of T lymphocyte anergy|positive regulation of T-lymphocyte anergy|stimulation of T cell anergy													biological_process											owl:Class	
GO:0062108	biolink:NamedThing	negative regulation of protein localization to non-growing cell tip	Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to a non-growing cell tip.	tmpzr1t_l9r_go_relaxed.owl								dph	2019-02-05T13:03:52Z					biological_process											owl:Class	
GO:0140039	biolink:NamedThing	cell-cell adhesion in response to extracellular stimulus	The attachment of one cell to another cell via adhesion molecules as a result of an extracellular stimulus.	tmpzr1t_l9r_go_relaxed.owl								pg	2017-05-24T11:37:30Z					biological_process											owl:Class	
GO:0010425	biolink:NamedThing	DNA methylation on cytosine within a CNG sequence	The covalent transfer of a methyl group, to C-5 or N-4, of a cytosine located within a CNG sequence in a DNA molecule. N stands for any nucleotide.	tmpzr1t_l9r_go_relaxed.owl	cytosine methylation within a CNG sequence													biological_process											owl:Class	
GO:0019909	biolink:NamedThing	[pyruvate dehydrogenase (lipoamide)] phosphatase regulator activity	Binds to and modulates of the activity of [pyruvate dehydrogenase (lipoamide)] phosphatase.	tmpzr1t_l9r_go_relaxed.owl	[pyruvate dehydrogenase (lipoamide)] phosphatase, intrinsic regulator activity													molecular_function											owl:Class	
GO:0047278	biolink:NamedThing	bilirubin-glucuronoside glucuronosyltransferase activity	Catalysis of the reaction: 2 bilirubin-glucuronoside = bilirubin + bilirubin-bisglucuronoside.	tmpzr1t_l9r_go_relaxed.owl	bilirubin monoglucuronide transglucuronidase activity|bilirubin-glucuronoside:bilirubin-glucuronoside D-glucuronosyltransferase activity|bilirubin glucuronoside glucuronosyltransferase activity				MetaCyc:2.4.1.95-RXN|KEGG_REACTION:R00062|RHEA:16885									molecular_function											owl:Class	
GO:1900620	biolink:NamedThing	acetate ester biosynthetic process	The chemical reactions and pathways resulting in the formation of an acetate esteran acetate ester, any carboxylic ester where the carboxylic acid component is acetic acid.	tmpzr1t_l9r_go_relaxed.owl	acetate ester synthesis|acetate ester formation|acetate ester biosynthesis|acetyl ester biosynthetic process|acetyl ester biosynthesis|acetate ester anabolism							bf	2012-05-16T12:30:12Z					biological_process											owl:Class	
GO:0106281	biolink:NamedThing	chenodeoxycholate 7-alpha-dehydrogenase (NAD+) activity	Catalysis of the reaction: chenodeoxycholate + NAD(+) = 7-oxolithocholate + H(+) + NADH.	tmpzr1t_l9r_go_relaxed.owl					RHEA:42036			hjd	2020-07-29T17:48:25Z					molecular_function											owl:Class	
GO:0031495	biolink:NamedThing	negative regulation of mating type switching	Any process that stops, prevents, or reduces the frequency, rate or extent of mating type switching.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of mating type switching|downregulation of mating type switching|inhibition of mating type switching|down regulation of mating type switching													biological_process											owl:Class	
GO:0050120	biolink:NamedThing	N-acetylhexosamine 1-dehydrogenase activity	Catalysis of the reaction: N-acetyl-D-glucosamine + H(2)O + NAD(+) = N-acetyl-D-glucosaminate + 2 H(+) + NADH.	tmpzr1t_l9r_go_relaxed.owl	N-acetylhexosamine dehydrogenase activity|N-acetyl-D-hexosamine dehydrogenase activity|N-acetyl-D-hexosamine:NAD+ 1-oxidoreductase activity				RHEA:23144|EC:1.1.1.240|KEGG_REACTION:R01202|MetaCyc:N-ACETYLHEXOSAMINE-1-DEHYDROGENASE-RXN									molecular_function											owl:Class	
GO:0031133	biolink:NamedThing	regulation of axon diameter	Any process that modulates the rate, direction or extent of axon growth such that the correct diameter is attained and maintained.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0043215	biolink:NamedThing	daunorubicin transport	The directed movement of daunorubicin, an anthracycline antibiotic produced by Streptomyces coeruleorubidus or S. peucetius and used as an antineoplastic into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0061335	biolink:NamedThing	cell growth involved in Malpighian tubule morphogenesis	The growth of an epithelial cell dependent on cycles of endoreplication, where growth contributes to the shaping of the Malpighian tubule.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-09-28T02:08:25Z					biological_process											owl:Class	
GO:0030264	biolink:NamedThing	nuclear fragmentation involved in apoptotic nuclear change	The breakdown of the nucleus into small membrane-bounded compartments, or blebs, each of which contain compacted DNA.	tmpzr1t_l9r_go_relaxed.owl	nuclear fragmentation during apoptosis|apoptotic nuclear fragmentation|nucleus fragmentation													biological_process											owl:Class	
GO:0001703	biolink:NamedThing	gastrulation with mouth forming first	A gastrulation process in which the initial invagination becomes the mouth and the anus forms second.	tmpzr1t_l9r_go_relaxed.owl	protostomic gastrulation													biological_process											owl:Class	
GO:0030395	biolink:NamedThing	lactose binding	Binding to lactose, a disaccharide of glucose and galactose, the carbohydrate of milk.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0048030	biolink:NamedThing	disaccharide binding	Binding to a disaccharide. Disaccharides are sugars composed of two monosaccharide units.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0031922	biolink:NamedThing	pyridoxamine transport	The directed movement of pyridoxamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Pyridoxamine, 4-(aminomethyl)-5-(hydroxymethyl)-2-methylpyridin-3-ol, is one of the vitamin B6 compounds. Pyridoxal, pyridoxamine and pyridoxine are collectively known as vitamin B6, and are efficiently converted to the biologically active form of vitamin B6, pyridoxal phosphate.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0031919	biolink:NamedThing	vitamin B6 transport	The directed movement of any of the vitamin B6 compounds -- pyridoxal, pyridoxamine and pyridoxine and the active form, pyridoxal phosphate -- into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0052026	biolink:NamedThing	modulation by symbiont of host transcription	Any process in which an organism modulates the frequency, rate or extent of its host's transcription. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:2000634	biolink:NamedThing	regulation of primary miRNA processing	Any process that modulates the frequency, rate or extent of primary microRNA processing.	tmpzr1t_l9r_go_relaxed.owl	regulation of primary microRNA processing|regulation of pri-miRNA processing							dph	2011-04-18T03:50:50Z					biological_process											owl:Class	
GO:0035755	biolink:NamedThing	cardiolipin hydrolase activity	Catalysis of the hydrolysis of cardiolipin (1,3-bis(3-phosphatidyl)glycerol), releasing phosphatidic acid (PA).	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/8492|https://github.com/geneontology/go-ontology/issues/21230			Reactome:R-HSA-8954398			bf	2011-03-24T10:14:05Z					molecular_function											owl:Class	
GO:0047642	biolink:NamedThing	aldose beta-D-fructosyltransferase activity	Catalysis of the reaction: alpha-D-aldosyl1 beta-D-fructoside + D-aldose2 = D-aldose1 + alpha-D-aldosyl2 beta-D-fructoside.	tmpzr1t_l9r_go_relaxed.owl	alpha-D-aldosyl-beta-D-fructoside:aldose 1-beta-D-fructosyltransferase activity|aldose b-D-fructosyltransferase activity				EC:2.4.1.162|MetaCyc:ALDOSE-BETA-FRUCTOSYLTRANSFERASE-RXN									molecular_function											owl:Class	
GO:0050738	biolink:NamedThing	fructosyltransferase activity	Catalysis of the transfer of a fructosyl group to an acceptor molecule, typically another carbohydrate or a lipid.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0035224	biolink:NamedThing	genital disc anterior/posterior pattern formation	The establishment, maintenance and elaboration of the anterior/posterior axis of the genital disc. An anterior and posterior compartment form in each of the three genital disc primoridia (the female genital disc primordium, the male genital disc primordium and the anal primordium).	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0035221	biolink:NamedThing	genital disc pattern formation	The process that gives rise to the patterns of cell differentiation that will arise in the genital imaginal disc.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0072203	biolink:NamedThing	cell proliferation involved in metanephros development	The multiplication or reproduction of cells, resulting in the expansion of the population in the metanephros.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-03-18T10:42:27Z					biological_process											owl:Class	
GO:0099156	biolink:NamedThing	cell-cell signaling via exosome	Cell-cell signaling in which the ligand is carried between cells by an exosome.	tmpzr1t_l9r_go_relaxed.owl	exosome mediated							dos	2017-07-05T16:40:45Z					biological_process											owl:Class	
GO:1904254	biolink:NamedThing	regulation of iron ion transmembrane transporter activity	Any process that modulates the frequency, rate or extent of an iron transmembrane transporter activity.	tmpzr1t_l9r_go_relaxed.owl	regulation of iron channel activity|regulation of iron cation channel activity|regulation of iron-specific channel activity							kom	2015-05-20T14:05:00Z					biological_process											owl:Class	
GO:1903014	biolink:NamedThing	cellular response to differentiation-inducing factor 1	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to DIF-1|cellular response to DIF1|DIF-1|cellular response to 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one							rjd	2014-05-14T16:18:18Z					biological_process											owl:Class	
GO:0006061	biolink:NamedThing	sorbitol biosynthetic process	The chemical reactions and pathways resulting in the formation of sorbitol (D-glucitol), one of the ten stereoisomeric hexitols. It can be derived from glucose by reduction of the aldehyde group.	tmpzr1t_l9r_go_relaxed.owl	sorbitol synthesis|sorbitol formation|sorbitol biosynthesis|sorbitol anabolism													biological_process											owl:Class	
GO:0030832	biolink:NamedThing	regulation of actin filament length	Any process that controls the length of actin filaments in a cell.	tmpzr1t_l9r_go_relaxed.owl						Note that the syntax of the definition of this term is different from the usual regulation syntax because it describes regulation of a trait rather than regulation of a process.								biological_process											owl:Class	
GO:0005367	biolink:NamedThing	myo-inositol:sodium symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: myo-inositol(out) + Na+(out) = myo-inositol(in) + Na+(in).	tmpzr1t_l9r_go_relaxed.owl	myo-inositol-sodium cotransporter activity				Reactome:R-HSA-429663									molecular_function											owl:Class	
GO:0090043	biolink:NamedThing	regulation of tubulin deacetylation	Any process that modulates the frequency, rate or extent of tubulin deacetylation. Tubulin deacetylation is the removal of an acetyl group from a protein amino acid.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-08-03T11:53:07Z					biological_process											owl:Class	
GO:0090311	biolink:NamedThing	regulation of protein deacetylation	Any process that modulates the rate, frequency, or extent of protein deacetylation, the removal of an acetyl group from a protein amino acid. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid.	tmpzr1t_l9r_go_relaxed.owl	regulation of protein amino acid deacetylation							tb	2010-04-14T01:30:45Z					biological_process											owl:Class	
GO:0097393	biolink:NamedThing	telomeric repeat-containing RNA transcription	The synthesis of telomeric repeat-containing RNA from a DNA template. A telomere is a complex of DNA and proteins that seals the end of a chromosome.	tmpzr1t_l9r_go_relaxed.owl	TERRA transcription							pr	2012-10-23T10:06:17Z					biological_process											owl:Class	
GO:0003403	biolink:NamedThing	optic vesicle formation	The developmental process pertaining to the initial formation of the optic vesicle from the lateral wall of the forebrain. This process begins with the specific processes that contribute to the appearance of the vesicle and ends when the vesicle has evaginated. The optic vesicle is the evagination of neurectoderm that precedes formation of the optic cup.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-12-21T01:42:37Z					biological_process											owl:Class	
GO:0090101	biolink:NamedThing	negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway	Any process that decreases the rate, frequency, or extent of the series of molecular signals generated as a consequence of a transmembrane receptor serine/threonine kinase binding to its physiological ligand.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of transmembrane receptor protein serine/threonine kinase signalling pathway							tb	2009-11-13T10:56:52Z					biological_process											owl:Class	
GO:0004151	biolink:NamedThing	dihydroorotase activity	Catalysis of the reaction: (S)-dihydroorotate + H(2)O = N-carbamoyl-L-aspartate + H(+).	tmpzr1t_l9r_go_relaxed.owl	DHOase activity|carbamoylaspartic dehydrase activity|dihydroorotate hydrolase activity|(S)-dihydroorotate amidohydrolase activity				EC:3.5.2.3|RHEA:24296|Reactome:R-HSA-73571|KEGG_REACTION:R01993|MetaCyc:DIHYDROOROT-RXN									molecular_function											owl:Class	
GO:0018916	biolink:NamedThing	nitrobenzene metabolic process	The chemical reactions and pathways involving nitrobenzene (nitrobenzol), a derivative of benzene with an NO2 group attached to the ring. It is a yellow aromatic liquid used in perfumery and manufactured in large quantities in the preparation of aniline.	tmpzr1t_l9r_go_relaxed.owl	nitrobenzene metabolism				UM-BBD_pathwayID:nb									biological_process											owl:Class	
GO:0031785	biolink:NamedThing	type 1A melatonin receptor binding	Binding to a type 1A melatonin receptor.	tmpzr1t_l9r_go_relaxed.owl	type 1A melatonin receptor ligand													molecular_function											owl:Class	
GO:0002057	biolink:NamedThing	guanine binding	Binding to guanine.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1900702	biolink:NamedThing	negative regulation of orcinol biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of orcinol biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	down regulation of orcinol biosynthetic process|down regulation of orcinol biosynthesis|negative regulation of orcinol biosynthesis|downregulation of orcinol formation|down regulation of orcinol formation|negative regulation of orcinol formation|inhibition of orcinol biosynthesis|inhibition of orcinol biosynthetic process|downregulation of orcinol synthesis|down-regulation of orcinol biosynthetic process|negative regulation of orcinol synthesis|inhibition of orcinol synthesis|inhibition of orcinol anabolism|down-regulation of orcinol biosynthesis|negative regulation of orcinol anabolism|down regulation of orcinol anabolism|downregulation of orcinol biosynthesis|down regulation of orcinol synthesis|downregulation of orcinol biosynthetic process|down-regulation of orcinol formation|downregulation of orcinol anabolism|down-regulation of orcinol anabolism|inhibition of orcinol formation|down-regulation of orcinol synthesis							di	2012-05-22T04:58:20Z					biological_process											owl:Class	
GO:0004499	biolink:NamedThing	N,N-dimethylaniline monooxygenase activity	Catalysis of the reaction: N,N-dimethylaniline + NADPH + H+ + O2 = N,N-dimethylaniline N-oxide + NADP+ + H2O.	tmpzr1t_l9r_go_relaxed.owl	dimethylaniline oxidase activity|methylphenyltetrahydropyridine N-monooxygenase activity|FAD-containing monooxygenase activity|flavin monooxygenase activity|FMO-I|FMO3|FMO2|FMO4|flavin mixed function oxidase activity|1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine:oxygen N-oxidoreductase activity|FMO-II|DMA oxidase activity|FMO1|flavin-containing monooxygenase activity|FMO5|Ziegler's enzyme|N,N-dimethylaniline,NADPH:oxygen oxidoreductase (N-oxide-forming)|dimethylaniline N-oxidase activity|mixed-function amine oxidase activity|FMO activity|dimethylaniline monooxygenase (N-oxide-forming) activity				RHEA:24468|MetaCyc:1.14.13.8-RXN|Reactome:R-HSA-217255|EC:1.14.13.8|Reactome:R-HSA-139970|Reactome:R-HSA-5602966							GO:0047076		molecular_function											owl:Class	
GO:0010917	biolink:NamedThing	negative regulation of mitochondrial membrane potential	Any process that stops, prevents, or reduces the frequency, rate or extent of establishment or extent of a mitochondrial membrane potential, the electric potential existing across any mitochondrial membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane.	tmpzr1t_l9r_go_relaxed.owl	reduction of mitochondrial membrane potential													biological_process											owl:Class	
GO:0050767	biolink:NamedThing	regulation of neurogenesis	Any process that modulates the frequency, rate or extent of neurogenesis, the generation of cells in the nervous system.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0035164	biolink:NamedThing	embryonic plasmatocyte differentiation	The process in which an embryonic mesoderm-derived hemocyte precursor cell acquires the specialized features of the phagocytic blood-cell type, the plasmatocyte.	tmpzr1t_l9r_go_relaxed.owl	embryonic plasmatocyte cell differentiation													biological_process											owl:Class	
GO:0032175	biolink:NamedThing	mating projection septin ring	A septin ring, i.e. a ring-shaped structure composed of septins and septin-associated proteins, located at the neck of a shmoo (mating projection). The septin ring in the neck of a shmoo may act as a barrier to localize mating factors in the shmoo tip.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0039680	biolink:NamedThing	actin-dependent intracellular transport of virus towards nucleus	The directed movement of a virus, or part of a virus, towards the host cell nucleus using actin filaments.	tmpzr1t_l9r_go_relaxed.owl	actin-dependent intracellular transport of viral material towards nucleus|actin-dependent inwards viral transport				VZ:991			bf	2013-10-10T11:24:56Z					biological_process											owl:Class	
GO:0075520	biolink:NamedThing	actin-dependent intracellular transport of virus	The directed movement of a virus, or part of a virus, within the host cell cytoplasm via the host's actin filaments. Actin-dependent transport is induced by viral proteins that interact with actin and/or host cell motor proteins like myosins or that promotes actin polymerization/depolymerization reactions.	tmpzr1t_l9r_go_relaxed.owl	actin-dependent intracellular transport of viral material				VZ:991			jl	2011-08-03T01:45:55Z					biological_process											owl:Class	
GO:0015503	biolink:NamedThing	glutathione-regulated potassium exporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: K+(in) + H+(out) = K+(out) + H+(in), where glutathione maintains the closed state.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0033532	biolink:NamedThing	stachyose biosynthetic process	The chemical reactions and pathways resulting in the formation of stachyose, the tetrasaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside.	tmpzr1t_l9r_go_relaxed.owl	stachyose synthesis|stachyose anabolism|stachyose biosynthesis|stachyose formation				MetaCyc:PWY-5337									biological_process											owl:Class	
GO:0043813	biolink:NamedThing	phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity	Catalysis of the reaction: phosphatidylinositol-3,5-bisphosphate + H2O = phosphatidylinositol-3-phosphate + orthophosphate.	tmpzr1t_l9r_go_relaxed.owl	phosphatidylinositol 3,5-bisphosphate 5-phosphatase activity				Reactome:R-HSA-1676005|Reactome:R-HSA-1675836|Reactome:R-HSA-1676020|Reactome:R-HSA-1676174									molecular_function											owl:Class	
GO:0106018	biolink:NamedThing	phosphatidylinositol-3,5-bisphosphate phosphatase activity	Catalysis of the reaction: 1-phosphatidyl-myo-inositol 3,5-bisphosphate + H2O = 1-phosphatidyl-1D-myo-inositol phosphate + phosphate.	tmpzr1t_l9r_go_relaxed.owl								hjd	2017-05-10T14:19:13Z					molecular_function											owl:Class	
GO:0071929	biolink:NamedThing	alpha-tubulin acetylation	The addition of an acetyl group to the lysine 40 residue of alpha-tubulin.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-09-28T01:46:38Z					biological_process											owl:Class	
GO:0032195	biolink:NamedThing	post-lysosomal vacuole	A membrane-bounded intracellular vesicle formed late in the endocytic pathway when the pH in the vacuole becomes neutral prior to exocytosis.	tmpzr1t_l9r_go_relaxed.owl	postlysosome|post-lysosome	https://github.com/geneontology/go-ontology/issues/22197												cellular_component											owl:Class	
GO:0035410	biolink:NamedThing	dihydrotestosterone 17-beta-dehydrogenase activity	Catalysis of the reaction: 5alpha-dihydrotestosterone + NAD+ = 5alpha-androstane-3,17-dione + NADH.	tmpzr1t_l9r_go_relaxed.owl					EC:1.1.1.51			bf	2010-03-24T10:48:41Z					molecular_function											owl:Class	
GO:0060834	biolink:NamedThing	oral/aboral axis specification	The establishment, maintenance and elaboration of a line that delineates the mouth and the anus of an embryo.	tmpzr1t_l9r_go_relaxed.owl	oral/aboral axis determination							dph	2009-08-11T03:25:26Z					biological_process											owl:Class	
GO:0000578	biolink:NamedThing	embryonic axis specification	The establishment, maintenance and elaboration of a pattern along a line or a point in an embryo.	tmpzr1t_l9r_go_relaxed.owl	embryonic axis determination													biological_process											owl:Class	
GO:0008603	biolink:NamedThing	cAMP-dependent protein kinase regulator activity	Modulation of the activity of the enzyme cAMP-dependent protein kinase.	tmpzr1t_l9r_go_relaxed.owl	3',5'-cAMP-dependent protein kinase regulator activity|cAMP-dependent protein kinase, intrinsic regulator activity|cyclic AMP-dependent protein kinase regulator activity|3',5' cAMP-dependent protein kinase regulator activity|adenosine 3',5'-cyclophosphate-dependent protein kinase regulator activity													molecular_function											owl:Class	
GO:0050687	biolink:NamedThing	negative regulation of defense response to virus	Any process that stops, prevents or reduces the rate or extent of antiviral mechanisms, thereby facilitating viral replication.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of antiviral response|downregulation of antiviral response|down regulation of antiviral response|inhibition of antiviral response|negative regulation of antiviral response													biological_process											owl:Class	
GO:0070486	biolink:NamedThing	leukocyte aggregation	The adhesion of one leukocyte to one or more other leukocytes via adhesion molecules.	tmpzr1t_l9r_go_relaxed.owl	immune cell aggregation|white corpuscle aggregation|white blood cell aggregation|leucocyte aggregation													biological_process											owl:Class	
GO:0034127	biolink:NamedThing	regulation of MyD88-independent toll-like receptor signaling pathway	Any process that modulates the frequency, rate, or extent of MyD88-independent toll-like receptor signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	regulation ofMyD88-independent toll-like receptor signalling pathway|regulation ofMyD88-independent TLR signaling pathway													biological_process											owl:Class	
GO:0004410	biolink:NamedThing	homocitrate synthase activity	Catalysis of the reaction: 2-oxoglutarate + acetyl-CoA + H(2)O = CoA + H(+) + homocitrate.	tmpzr1t_l9r_go_relaxed.owl	2-hydroxybutane-1,2,4-tricarboxylate 2-oxoglutarate-lyase (CoA-acetylating)|acetyl-CoA:2-oxoglutarate C-acetyltransferase (thioester-hydrolysing, carboxymethyl forming)|2-hydroxybutane-1,2,4-tricarboxylate 2-oxoglutarate-lyase (CoA- acetylating) activity|acetyl-coenzyme A:2-ketoglutarate C-acetyl transferase activity|homocitrate synthetase activity				MetaCyc:HOMOCITRATE-SYNTHASE-RXN|EC:2.3.3.14|KEGG_REACTION:R00271|RHEA:12929	Note that this function was formerly EC:4.1.3.21.								molecular_function											owl:Class	
GO:1901696	biolink:NamedThing	cannabinoid biosynthetic process	The chemical reactions and pathways resulting in the formation of cannabinoid.	tmpzr1t_l9r_go_relaxed.owl	cannabinoid anabolism|cannabinoid formation|cannabinoid biosynthesis|cannabinoid synthesis							ms	2012-12-13T08:07:47Z					biological_process											owl:Class	
GO:0097153	biolink:NamedThing	cysteine-type endopeptidase activity involved in apoptotic process	Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile, and contributing to the apoptotic process.	tmpzr1t_l9r_go_relaxed.owl	caspase activity|metacaspase activity				Reactome:R-HSA-6800797			pr	2011-09-09T10:21:56Z					molecular_function											owl:Class	
GO:0061794	biolink:NamedThing	conidium development	The process whose specific outcome is the progression of conidium over time, from its formation to the mature structure. Conidia are non-motile spores produced via mitotic asexual reproduction in higher fungi; they are haploid cells genetically identical to their haploid parent. They are produced by conversion of hyphal elements, or are borne on sporogenous cells on or within specialized structures termed conidiophores, and participate in dispersal of the fungus.	tmpzr1t_l9r_go_relaxed.owl								dph	2016-09-17T09:53:51Z					biological_process											owl:Class	
GO:0002555	biolink:NamedThing	histamine secretion by platelet	The regulated release of histamine by a platelet or group of platelets.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0071680	biolink:NamedThing	response to indole-3-methanol	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an indole-3-methanol stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to indole-3-carbinol							mah	2010-02-18T04:05:09Z					biological_process											owl:Class	
GO:0019897	biolink:NamedThing	extrinsic component of plasma membrane	The component of a plasma membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.	tmpzr1t_l9r_go_relaxed.owl	peripheral plasma membrane protein|juxtamembrane|extrinsic to plasma membrane											GO:0000157		cellular_component											owl:Class	
GO:0035106	biolink:NamedThing	operant conditioning	Learning to anticipate future events on the basis of past experience with the consequences of one's own behavior.	tmpzr1t_l9r_go_relaxed.owl	instrumental conditioning				Wikipedia:Operant_conditioning									biological_process											owl:Class	
GO:0010137	biolink:NamedThing	ureide biosynthetic process	The chemical reactions and pathways resulting in the formation of ureide, the organic form of nitrogen in nitrogen fixing and transporting plants, from IMP, which is synthesized de novo during nitrogen fixation by roots.	tmpzr1t_l9r_go_relaxed.owl	ureide formation|ureide biosynthesis|ureide anabolism|ureide synthesis				MetaCyc:URSIN-PWY									biological_process											owl:Class	
GO:0004632	biolink:NamedThing	phosphopantothenate--cysteine ligase activity	Catalysis of the reaction: CTP + (R)-4'-phosphopantothenate + L-cysteine = CMP + diphosphate + (R)-4'-phosphopantothenoyl-L-cysteine. Cysteine can be replaced by some of its derivatives.	tmpzr1t_l9r_go_relaxed.owl	(R)-4'-phosphopantothenate:L-cysteine ligase activity|phosphopantothenoylcysteine synthetase activity|phosphopantothenate-cysteine ligase activity				RHEA:19397|Reactome:R-HSA-196753|MetaCyc:P-PANTOCYSLIG-RXN|EC:6.3.2.5									molecular_function											owl:Class	
GO:0046777	biolink:NamedThing	protein autophosphorylation	The phosphorylation by a protein of one or more of its own amino acid residues (cis-autophosphorylation), or residues on an identical protein (trans-autophosphorylation).	tmpzr1t_l9r_go_relaxed.owl	protein amino acid autophosphorylation				Wikipedia:Autophosphorylation									biological_process											owl:Class	
GO:0150167	biolink:NamedThing	positive regulation of histone H3-K4 acetylation	Any process that activates or increases the frequency, rate or extent of histone H3-K4 acetylation.	tmpzr1t_l9r_go_relaxed.owl								bc	2020-01-14T12:32:18Z					biological_process											owl:Class	
GO:0019301	biolink:NamedThing	rhamnose catabolic process	The chemical reactions and pathways resulting in the breakdown of rhamnose, the hexose 6-deoxy-L-mannose.	tmpzr1t_l9r_go_relaxed.owl	rhamnose breakdown|rhamnose degradation|rhamnose catabolism				MetaCyc:RHAMCAT-PWY									biological_process											owl:Class	
GO:0071314	biolink:NamedThing	cellular response to cocaine	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cocaine stimulus. Cocaine is a crystalline alkaloid obtained from the leaves of the coca plant.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-12-10T04:53:20Z					biological_process											owl:Class	
GO:0018688	biolink:NamedThing	DDT 2,3-dioxygenase activity	Catalysis of the reaction: 1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane + O2 + 2 H+ + 2 e- = cis-2,3-dihydrodiol DDT. 1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane is also known as DDT.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0450									molecular_function											owl:Class	
GO:0060499	biolink:NamedThing	fibroblast growth factor receptor signaling pathway involved in lung induction	The series of molecular signals generated as a consequence of a fibroblast growth factor-type receptor binding to one of its physiological ligands resulting in the formation of the lung bud along the lateral-esophageal sulcus.	tmpzr1t_l9r_go_relaxed.owl	fibroblast growth factor receptor signalling pathway involved in lung induction													biological_process											owl:Class	
GO:0022836	biolink:NamedThing	gated channel activity	Enables the transmembrane transfer of a solute by a channel that opens in response to a specific stimulus.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0097137	biolink:NamedThing	BAD-BCL-xl complex	A heterodimeric protein complex consisting of BAD and BCL-xl, members of the Bcl-2 family of anti- and proapoptotic regulators.	tmpzr1t_l9r_go_relaxed.owl								pr	2011-08-02T01:36:06Z					cellular_component											owl:Class	
GO:0080132	biolink:NamedThing	fatty acid alpha-hydroxylase activity	Catalysis of the conversion of a fatty acid to an alpha-hydroxylated fatty acid. A hydroxyl group is added to the second carbon, counted from the carboxyl end, of a fatty acid chain.	tmpzr1t_l9r_go_relaxed.owl	fatty acid 2-hydroxylase				Reactome:R-HSA-5693761			dhl	2009-05-06T04:43:36Z					molecular_function											owl:Class	
GO:0090308	biolink:NamedThing	regulation of DNA methylation-dependent heterochromatin assembly	Any process that modulates the rate, frequency, or extent of the repression of transcription by methylation of DNA, leading to the formation of heterochromatin.	tmpzr1t_l9r_go_relaxed.owl	regulation of methylation-dependent chromatin silencing							tb	2010-04-09T02:12:53Z					biological_process											owl:Class	
GO:1900983	biolink:NamedThing	vindoline metabolic process	The chemical reactions and pathways involving vindoline.	tmpzr1t_l9r_go_relaxed.owl	vindoline metabolism							yaf	2012-06-14T09:16:29Z					biological_process											owl:Class	
GO:0045329	biolink:NamedThing	carnitine biosynthetic process	The chemical reactions and pathways resulting in the formation of carnitine (hydroxy-trimethyl aminobutyric acid), a compound that participates in the transfer of acyl groups across the inner mitochondrial membrane.	tmpzr1t_l9r_go_relaxed.owl	vitamin Bt biosynthetic process|carnitine formation|carnitine biosynthesis|carnitine anabolism|carnitine synthesis|vitamin Bt biosynthesis													biological_process											owl:Class	
GO:0016129	biolink:NamedThing	phytosteroid biosynthetic process	The chemical reactions and pathways resulting in the formation of phytosteroids, steroids that differ from animal steroids in having substitutions at C24 and/or a double bond at C22. Phytosteroids are so named because they occur in higher plants; some, notably ergosterol, are also found in fungi.	tmpzr1t_l9r_go_relaxed.owl	phytosteroid synthesis|phytosteroid formation|phytosteroid anabolism|phytosteroid biosynthesis													biological_process											owl:Class	
GO:0015733	biolink:NamedThing	shikimate transmembrane transport	The process in which shikimate is transported across a lipid bilayer, from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	shikimate transport													biological_process											owl:Class	
GO:0052746	biolink:NamedThing	inositol phosphorylation	The process of introducing one or more phosphate groups into inositol. Inositol is the cyclic alcohol 1,2,3,4,5,6-cyclohexanehexol, which is widely distributed in nature and acts as a growth factor in animals and microorganisms.	tmpzr1t_l9r_go_relaxed.owl	inositol and derivative phosphorylation|myo-inositol and derivative phosphorylation|myo-inositol phosphorylation							ai	2011-09-14T01:55:23Z					biological_process											owl:Class	
GO:0061853	biolink:NamedThing	regulation of neuroblast migration	Any process that modulates the frequency, rate or extent of neuroblast migration.	tmpzr1t_l9r_go_relaxed.owl								dph	2017-03-08T18:17:07Z					biological_process											owl:Class	
GO:0046150	biolink:NamedThing	melanin catabolic process	The chemical reactions and pathways resulting in the breakdown of melanins, pigments largely of animal origin. High molecular weight polymers of indole quinone, they are irregular polymeric structures and are divided into three groups: allomelanins in the plant kingdom and eumelanins and phaeomelanins in the animal kingdom.	tmpzr1t_l9r_go_relaxed.owl	melanin catabolism|melanin degradation|melanin breakdown													biological_process											owl:Class	
GO:0006582	biolink:NamedThing	melanin metabolic process	The chemical reactions and pathways involving melanins, pigments largely of animal origin. High molecular weight polymers of indole quinone, they are irregular polymeric structures and are divided into three groups: allomelanins in the plant kingdom and eumelanins and phaeomelanins in the animal kingdom.	tmpzr1t_l9r_go_relaxed.owl	melanin metabolism													biological_process											owl:Class	
GO:0012508	biolink:NamedThing	Golgi to ER transport vesicle membrane	The lipid bilayer surrounding a vesicle transporting substances from the Golgi to the ER.	tmpzr1t_l9r_go_relaxed.owl	Golgi-ER transport vesicle membrane|Golgi-endoplasmic reticulum transport vesicle membrane|Golgi to endoplasmic reticulum transport vesicle membrane|Golgi to ER constitutive secretory pathway transport vesicle membrane													cellular_component											owl:Class	
GO:0051720	biolink:NamedThing	DNA (cytosine-5-)-methyltransferase activity, acting on CpNpG substrates	Catalysis of the reaction: S-adenosyl-L-methionine + DNA containing CpNpG = S-adenosyl-L-homocysteine + DNA containing 5-MeCpNpG.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0002801	biolink:NamedThing	negative regulation of antifungal peptide secretion	Any process that stops, prevents, or reduces the frequency, rate, or extent of antifungal peptide secretion.	tmpzr1t_l9r_go_relaxed.owl	inhibition of antifungal peptide secretion|downregulation of antifungal peptide secretion|down-regulation of antifungal peptide secretion|down regulation of antifungal peptide secretion													biological_process											owl:Class	
GO:1903215	biolink:NamedThing	negative regulation of protein targeting to mitochondrion	Any process that stops, prevents or reduces the frequency, rate or extent of protein targeting to mitochondrion.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of mitochondrial translocation|negative regulation of protein-mitochondrial targeting|down-regulation of protein-mitochondrial targeting|down-regulation of mitochondrial translocation|inhibition of protein-mitochondrial targeting|downregulation of protein-mitochondrial targeting|inhibition of protein import into mitochondrion|down-regulation of protein targeting to mitochondria|down regulation of mitochondrial protein import|downregulation of mitochondrial translocation|down regulation of protein-mitochondrial targeting|down regulation of mitochondrial translocation|downregulation of protein targeting to mitochondria|down-regulation of protein import into mitochondrion|inhibition of mitochondrial translocation|inhibition of protein targeting to mitochondrion|inhibition of mitochondrial protein import|down regulation of protein targeting to mitochondrion|negative regulation of protein targeting to mitochondria|negative regulation of protein import into mitochondrion|downregulation of mitochondrial protein import|down regulation of protein import into mitochondrion|downregulation of protein targeting to mitochondrion|downregulation of protein import into mitochondrion|down-regulation of protein targeting to mitochondrion|down-regulation of mitochondrial protein import|inhibition of protein targeting to mitochondria|down regulation of protein targeting to mitochondria|negative regulation of mitochondrial protein import							bf	2014-07-24T10:17:19Z					biological_process											owl:Class	
GO:0071288	biolink:NamedThing	cellular response to mercury ion	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mercury ion stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to mercury|cellular response to mercuric ion							mah	2009-12-10T04:06:37Z					biological_process											owl:Class	
GO:0046689	biolink:NamedThing	response to mercury ion	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mercury ion stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to mercury|mercuric sensitivity/resistance|response to mercuric ion													biological_process											owl:Class	
GO:0050915	biolink:NamedThing	sensory perception of sour taste	The series of events required to receive a sour taste stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.	tmpzr1t_l9r_go_relaxed.owl	sour taste perception													biological_process											owl:Class	
GO:0050909	biolink:NamedThing	sensory perception of taste	The series of events required for an organism to receive a gustatory stimulus, convert it to a molecular signal, and recognize and characterize the signal. Gustation involves the direct detection of chemical composition, usually through contact with chemoreceptor cells. This is a neurological process.	tmpzr1t_l9r_go_relaxed.owl	sense of taste|gustation|taste|taste perception				Wikipedia:Taste									biological_process											owl:Class	
GO:0047551	biolink:NamedThing	2-oxoaldehyde dehydrogenase (NAD+) activity	Catalysis of the reaction: a 2-oxoaldehyde + NAD+ + H2O = a 2-oxo acid + NADH + H+.	tmpzr1t_l9r_go_relaxed.owl	methylglyoxal dehydrogenase activity|alpha-ketoaldehyde dehydrogenase activity|2-oxoaldehyde dehydrogenase (NAD+)|2-oxoaldehyde:NAD+ 2-oxidoreductase activity|NAD-linked alpha-ketoaldehyde dehydrogenase activity|2-ketoaldehyde dehydrogenase|NAD-dependent alpha-ketoaldehyde dehydrogenase activity				MetaCyc:2-OXOALDEHYDE-DEHYDROGENASE-NAD+-RXN|RHEA:22276|Wikipedia:2-oxoaldehyde_dehydrogenase_(NAD+)|EC:1.2.1.23									molecular_function											owl:Class	
GO:0045176	biolink:NamedThing	apical protein localization	Any process in which a protein is transported to, or maintained in, apical regions of the cell.	tmpzr1t_l9r_go_relaxed.owl	apical protein localisation|establishment and maintenance of protein localization in apical part of cell|establishment and maintenance of apical protein localization													biological_process											owl:Class	
GO:0060222	biolink:NamedThing	regulation of retinal cone cell fate commitment	Any process that modulates the process in which a cell becomes committed to a retinal cone cell fate. Retinal cone cell fate commitment is the process in which the developmental fate of a cell becomes restricted such that it will develop into a retinal cone cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0018492	biolink:NamedThing	carbon-monoxide dehydrogenase (acceptor) activity	Catalysis of the reaction: CO + H2O + acceptor = CO2 + reduced acceptor.	tmpzr1t_l9r_go_relaxed.owl	anaerobic carbon monoxide dehydrogenase activity|carbon-monoxide:acceptor oxidoreductase activity|carbon monoxide dehydrogenase activity				MetaCyc:CARBON-MONOXIDE-DEHYDROGENASE-RXN|EC:1.2.7.4|RHEA:21040|UM-BBD_enzymeID:e0415									molecular_function											owl:Class	
GO:0018538	biolink:NamedThing	epoxide carboxylase activity	Catalysis of the generic reaction: epoxide + CO2 + NAD+ + electron donor = beta-keto acid + NADH + reduced electron donor; the electron donor may be NADPH or a dithiol. This reaction is the ring opening and carboxylation of an epoxide; for example: epoxypropane + CO2 + NAD+ + NADPH = acetoacetate + NADH + NADP+.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0004651	biolink:NamedThing	polynucleotide 5'-phosphatase activity	Catalysis of the reaction: 5'-phosphopolynucleotide + H2O = polynucleotide + phosphate.	tmpzr1t_l9r_go_relaxed.owl	polynucleotide 5'-triphosphatase activity|5'-polynucleotidase activity|polynucleotide 5'-phosphohydrolase activity				Reactome:R-HSA-77078|RHEA:11008|EC:3.1.3.33|MetaCyc:POLYNUCLEOTIDE-5-PHOSPHATASE-RXN									molecular_function											owl:Class	
GO:0098699	biolink:NamedThing	structural constituent of presynaptic actin cytoskeleton	The action of a molecule that contributes to the structural integrity of a presynaptic actin cytoskeleton.	tmpzr1t_l9r_go_relaxed.owl								dos	2017-06-09T18:33:07Z					molecular_function											owl:Class	
GO:0032457	biolink:NamedThing	fast endocytic recycling	The directed movement of membrane-bounded vesicles from peripheral endocytic compartments back to the plasma membrane where they are recycled for further rounds of transport.	tmpzr1t_l9r_go_relaxed.owl	direct endocytic recycling													biological_process											owl:Class	
GO:0043082	biolink:NamedThing	megagametophyte egg cell nucleus	The nucleus of a plant egg cell. This nucleus is found at the micropylar end of the embryo.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0042372	biolink:NamedThing	phylloquinone biosynthetic process	The chemical reactions and pathways resulting in the formation of phylloquinone, vitamin K1, a quinone-derived compound synthesized by green plants.	tmpzr1t_l9r_go_relaxed.owl	vitamin K1 biosynthetic process|phytylmenaquinone biosynthesis|phytonadione biosynthesis|phylloquinone synthesis|phytomenadione biosynthetic process|phylloquinone biosynthesis|vitamin K1 biosynthesis|phylloquinone anabolism|phylloquinone formation|phytomenadione biosynthesis|phytylmenaquinone biosynthetic process|phytonadione biosynthetic process				MetaCyc:PWY-5027									biological_process											owl:Class	
GO:0030449	biolink:NamedThing	regulation of complement activation	Any process that modulates the frequency, rate or extent of complement activation.	tmpzr1t_l9r_go_relaxed.owl	regulation of complement cascade													biological_process											owl:Class	
GO:0010774	biolink:NamedThing	meiotic strand invasion involved in reciprocal meiotic recombination	The cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate resulting in meiotic recombination. Meiotic recombination is the cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0030911	biolink:NamedThing	TPR domain binding	Binding to a tetratricopeptide repeat (TPR) domain of a protein, the consensus sequence of which is defined by a pattern of small and large hydrophobic amino acids and a structure composed of helices.	tmpzr1t_l9r_go_relaxed.owl	tetratricopeptide repeat domain binding													molecular_function											owl:Class	
GO:1990238	biolink:NamedThing	double-stranded DNA endodeoxyribonuclease activity	Catalysis of the hydrolysis of ester linkages within a double-stranded deoxyribonucleic acid molecule by creating internal breaks.	tmpzr1t_l9r_go_relaxed.owl	dsDNA-specific endodeoxyribonuclease activity							pg	2013-11-15T00:59:42Z					molecular_function											owl:Class	
GO:0043575	biolink:NamedThing	detection of osmotic stimulus	The series of events in which a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell is received and converted into a molecular signal.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0009442	biolink:NamedThing	allantoin assimilation pathway	The pathways by which allantoin is processed and converted to ureidoglycolate, and then into metabolically useful substrates. E. coli are able to utilize allantoin as a sole nitrogen source under anaerobic conditions by converting it to ureidoglycolate; this may be further metabolized to produce glyoxylate and thence 3-phosphoglycerate, or alternatively oxidized to oxolureate, which can converted into oxamate and carbamoylphosphate. This may then be further metabolized to CO2, NH4+ and ATP.	tmpzr1t_l9r_go_relaxed.owl	allantoin degradation pathway|allantoin catabolism via ureidoglycolate|allantoin catabolic process via ureidoglycolate				MetaCyc:PWY0-41									biological_process											owl:Class	
GO:0006012	biolink:NamedThing	galactose metabolic process	The chemical reactions and pathways involving galactose, the aldohexose galacto-hexose. D-galactose is widely distributed in combined form in plants, animals and microorganisms as a constituent of oligo- and polysaccharides; it also occurs in galactolipids and as its glucoside in lactose and melibiose.	tmpzr1t_l9r_go_relaxed.owl	galactose metabolism				Wikipedia:Galactose									biological_process											owl:Class	
GO:0008794	biolink:NamedThing	arsenate reductase (glutaredoxin) activity	Catalysis of the reaction: arsenate + reduced glutaredoxin = arsenite + oxidized glutaredoxin. Glutaredoxin functions as the electron donor for arsenate reduction. The electron flow therefore is ( NADPH -> glutathione reductase (EC:1.6.4.2) -> ) glutathione -> glutaredoxin -> arsenate reductase, i.e. glutathione is reduced by glutathione reductase and glutaredoxin is reduced by glutathione.	tmpzr1t_l9r_go_relaxed.owl	glutharedoxin:arsenate oxidoreductase activity				EC:1.20.4.1|UM-BBD_reactionID:r0635|MetaCyc:RXN-982|RHEA:22016									molecular_function											owl:Class	
GO:0042705	biolink:NamedThing	ocellus photoreceptor cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a photoreceptor cell found in the ocellus.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0019600	biolink:NamedThing	toluene oxidation	The chemical reactions and pathways resulting in the loss of electrons from one or more atoms in toluene.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0051497	biolink:NamedThing	negative regulation of stress fiber assembly	Any process that stops, prevents, or reduces the frequency, rate or extent of the assembly a stress fiber, a bundle of microfilaments and other proteins found in fibroblasts.	tmpzr1t_l9r_go_relaxed.owl	downregulation of stress fiber formation|negative regulation of stress fibre formation|down-regulation of stress fiber formation|negative regulation of stress fibre biosynthesis|down regulation of stress fiber formation|inhibition of stress fiber formation													biological_process											owl:Class	
GO:0045972	biolink:NamedThing	negative regulation of juvenile hormone secretion	Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of juvenile hormone.	tmpzr1t_l9r_go_relaxed.owl	down regulation of juvenile hormone secretion|inhibition of juvenile hormone secretion|downregulation of juvenile hormone secretion|down-regulation of juvenile hormone secretion													biological_process											owl:Class	
GO:0007558	biolink:NamedThing	regulation of juvenile hormone secretion	Any process that modulates the frequency, rate or extent of juvenile hormone secretion.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:2000434	biolink:NamedThing	regulation of protein neddylation	Any process that modulates the frequency, rate or extent of protein neddylation.	tmpzr1t_l9r_go_relaxed.owl	regulation of RUB1-protein conjugation							vw	2011-03-03T02:05:22Z					biological_process											owl:Class	
GO:0008409	biolink:NamedThing	5'-3' exonuclease activity	Catalysis of the hydrolysis of ester linkages within nucleic acids by removing nucleotide residues from the 5' end.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-5358599|Reactome:R-HSA-5358619									molecular_function											owl:Class	
GO:0060432	biolink:NamedThing	lung pattern specification process	Any developmental process that results in the creation of defined areas or spaces within the lung, to which cells respond and eventually are instructed to differentiate.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0075306	biolink:NamedThing	regulation of conidium formation	Any process that modulates the frequency, rate or extent of conidium formation, a process of producing non-motile spores, called conidia, via mitotic asexual reproduction in higher fungi. Conidia are haploid cells genetically identical to their haploid parent. They are produced by conversion of hyphal elements, or are borne on sporogenous cells on or within specialized structures termed conidiophores, and participate in dispersal of the fungus.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0034305	biolink:NamedThing	regulation of asexual sporulation	Any process that modulates the frequency, rate or extent of spore formation from the products of mitosis.	tmpzr1t_l9r_go_relaxed.owl	regulation of mitotic spore formation|regulation of mitotic sporulation|regulation of asexual spore formation													biological_process											owl:Class	
GO:0090353	biolink:NamedThing	polygalacturonase inhibitor activity	Binds to and stops, prevents or reduces the activity of polygalacturonase.	tmpzr1t_l9r_go_relaxed.owl								tb	2010-06-15T04:19:49Z					molecular_function											owl:Class	
GO:0018537	biolink:NamedThing	coenzyme F420-dependent N5,N10-methenyltetrahydromethanopterin reductase activity	Catalysis of the reaction: 5-methyltetrahydromethanopterin + coenzyme F420 + H(+) = 5,10-methylenetetrahydromethanopterin + reduced coenzyme F420.	tmpzr1t_l9r_go_relaxed.owl	methylene-H4MPT reductase activity|N(5),N(10)-methylenetetrahydromethanopterin reductase activity|N(5),N(10)-methylenetetrahydromethanopterin:coenzyme-F420 oxidoreductase activity|N5,N10-methylenetetrahydromethanopterin reductase activity|methylenetetrahydromethanopterin reductase activity|5,10-methylenetetrahydromethanopterin cyclohydrolase activity|coenzyme F420-dependent N(5),N(10)-methenyltetrahydromethanopterin reductase activity|N5,N10-methylenetetrahydromethanopterin:coenzyme-F420 oxidoreductase activity|methylene-H(4)MPT reductase activity|5-methyltetrahydromethanopterin:coenzyme-F420 oxidoreductase activity|5,10-methylenetetrahydromethanopterin reductase activity				UM-BBD_reactionID:r0354|EC:1.5.98.2|RHEA:21144|MetaCyc:METHELENE-THMPT-OXI-RXN|KEGG_REACTION:R04464									molecular_function											owl:Class	
GO:0002647	biolink:NamedThing	negative regulation of central tolerance induction	Any process that stops, prevents, or reduces the frequency, rate, or extent of central tolerance induction.	tmpzr1t_l9r_go_relaxed.owl	inhibition of central tolerance induction|downregulation of central tolerance induction|down regulation of central tolerance induction|down-regulation of central tolerance induction													biological_process											owl:Class	
GO:0050047	biolink:NamedThing	leucine 2,3-aminomutase activity	Catalysis of the reaction: L-leucine = (3R)-beta-leucine.	tmpzr1t_l9r_go_relaxed.owl	(2S)-alpha-leucine 2,3-aminomutase activity				EC:5.4.3.7|KEGG_REACTION:R01091|MetaCyc:LEUCINE-23-AMINOMUTASE-RXN|RHEA:10284									molecular_function											owl:Class	
GO:0002239	biolink:NamedThing	response to oomycetes	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from an oomycetes.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0102870	biolink:NamedThing	7-hydroxyflavone-glucosyltransferase activity	Catalysis of the reaction: UDP-alpha-D-glucose + 7-hydroxyflavone <=> 7-O-beta-D-glucosyl-7-hydroxyflavone + UDP + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-8355									molecular_function											owl:Class	
GO:1990853	biolink:NamedThing	histone H2A SQE motif phosphorylation	The modification of histone H2A by the addition of an phosphate group to the serine residue in the SQE motif of the histone.	tmpzr1t_l9r_go_relaxed.owl								al	2015-09-15T15:18:02Z					biological_process											owl:Class	
GO:0032550	biolink:NamedThing	purine ribonucleoside binding	Binding to a purine ribonucleoside, a compound consisting of a purine base linked to ribose.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0097722	biolink:NamedThing	sperm motility	Any process involved in the controlled movement of a sperm cell.	tmpzr1t_l9r_go_relaxed.owl	sperm movement							pr	2016-09-01T12:00:45Z					biological_process											owl:Class	
GO:0042597	biolink:NamedThing	periplasmic space	The region between the inner (cytoplasmic) and outer membrane (Gram-negative Bacteria) or cytoplasmic membrane and cell wall (Fungi and Gram-positive Bacteria).	tmpzr1t_l9r_go_relaxed.owl	periplasm											GO:0005620		cellular_component											owl:Class	
GO:2000800	biolink:NamedThing	regulation of endocardial cushion to mesenchymal transition involved in heart valve formation	Any process that modulates the frequency, rate or extent of endocardial cushion to mesenchymal transition involved in heart valve formation.	tmpzr1t_l9r_go_relaxed.owl	regulation of endocardial cushion to mesenchymal transition involved in valve formation							bf	2011-07-01T12:31:18Z					biological_process											owl:Class	
GO:0046050	biolink:NamedThing	UMP catabolic process	The chemical reactions and pathways resulting in the breakdown of UMP, uridine monophosphate.	tmpzr1t_l9r_go_relaxed.owl	UMP breakdown|UMP degradation|UMP catabolism													biological_process											owl:Class	
GO:0009222	biolink:NamedThing	pyrimidine ribonucleotide catabolic process	The chemical reactions and pathways resulting in the breakdown of a pyrimidine ribonucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.	tmpzr1t_l9r_go_relaxed.owl	pyrimidine ribonucleotide degradation|pyrimidine ribonucleotide breakdown|pyrimidine ribonucleotide catabolism													biological_process											owl:Class	
GO:0005925	biolink:NamedThing	focal adhesion	A cell-substrate junction that anchors the cell to the extracellular matrix and that forms a point of termination of actin filaments. In insects focal adhesion has also been referred to as hemi-adherens junction (HAJ).	tmpzr1t_l9r_go_relaxed.owl	focal contact|hemi-adherens junction|adhesion plaque|connecting hemi-adherens junction|HAJ				Wikipedia:Focal_adhesion							GO:0005926|GO:0008357		cellular_component											owl:Class	
GO:0102050	biolink:NamedThing	indole-3-acetyl-tyrosine synthetase activity	Catalysis of the reaction: indole-3-acetate + L-tyrosine + ATP(4-) <=> H+ + indole-3-acetyl-tyrosine + AMP(2-) + diphosphoric acid.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-10432									molecular_function											owl:Class	
GO:0001905	biolink:NamedThing	activation of membrane attack complex	The activation of the membrane attack complex components of the complement cascade which can result in death of a target cell through cytolysis.	tmpzr1t_l9r_go_relaxed.owl	MAC formation|membrane attack complex assembly|membrane attack complex formation|activation of terminal complement complex|MAC assembly|activation of the terminal complement cascade|activation of MAC|activation of TCC													biological_process											owl:Class	
GO:0007635	biolink:NamedThing	chemosensory behavior	Behavior that is dependent upon the sensation of chemicals.	tmpzr1t_l9r_go_relaxed.owl	behavioural response to chemical stimulus|chemosensory behaviour|behavioral response to chemical stimulus													biological_process											owl:Class	
GO:0001958	biolink:NamedThing	endochondral ossification	Replacement ossification wherein bone tissue replaces cartilage.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Endochondral_ossification									biological_process											owl:Class	
GO:1901190	biolink:NamedThing	regulation of formation of translation initiation ternary complex	Any process that modulates the frequency, rate or extent of formation of translation initiation ternary complex.	tmpzr1t_l9r_go_relaxed.owl	regulation of translation initiation ternary complex assembly							ss	2012-07-25T02:26:58Z					biological_process											owl:Class	
GO:1904618	biolink:NamedThing	positive regulation of actin binding	Any process that activates or increases the frequency, rate or extent of actin binding.	tmpzr1t_l9r_go_relaxed.owl	up regulation of membrane associated actin binding|up-regulation of actin binding|activation of actin binding|activation of membrane associated actin binding|up regulation of actin binding|upregulation of membrane associated actin binding|up-regulation of membrane associated actin binding|upregulation of actin binding|positive regulation of membrane associated actin binding							mr	2015-08-27T19:09:08Z					biological_process											owl:Class	
GO:0030212	biolink:NamedThing	hyaluronan metabolic process	The chemical reactions and pathways involving hyaluronan, the naturally occurring anionic form of hyaluronic acid, any member of a group of glycosaminoglycans, the repeat units of which consist of beta-1,4 linked D-glucuronyl-beta-(1,3)-N-acetyl-D-glucosamine.	tmpzr1t_l9r_go_relaxed.owl	hyaluronan metabolism													biological_process											owl:Class	
GO:0002604	biolink:NamedThing	regulation of dendritic cell antigen processing and presentation	Any process that modulates the frequency, rate, or extent of dendritic cell antigen processing and presentation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0002113	biolink:NamedThing	interleukin-33 binding	Binding to interleukin-33.	tmpzr1t_l9r_go_relaxed.owl	IL-33 binding													molecular_function											owl:Class	
GO:0045544	biolink:NamedThing	gibberellin 20-oxidase activity	Catalysis of the oxidation of C-20 gibberellins to form the corresponding C-19 lactones.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1901954	biolink:NamedThing	regulation of retrograde dense core granule transport	Any process that modulates the frequency, rate or extent of retrograde dense core granule transport.	tmpzr1t_l9r_go_relaxed.owl								pr	2013-02-19T13:36:43Z					biological_process											owl:Class	
GO:0060328	biolink:NamedThing	cytoplasmic actin-based contraction involved in forward cell motility	The actin filament-based movement by which cytoplasmic actin filaments slide past one another resulting in a contraction that propels the cell in the direction that has been defined as the front of the cell.	tmpzr1t_l9r_go_relaxed.owl	cytoplasmic actin-based contraction involved in forward cell locomotion													biological_process											owl:Class	
GO:0060327	biolink:NamedThing	cytoplasmic actin-based contraction involved in cell motility	The actin filament-based movement by which cytoplasmic actin filaments slide past one another resulting in a contraction that propels the cell from one place to another.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0097662	biolink:NamedThing	SCF-Das1 ubiquitin ligase complex	An SCF ubiquitin ligase complex in which the F-box protein is Das1 in S. cerevisiae.	tmpzr1t_l9r_go_relaxed.owl								pr	2014-10-06T10:26:27Z					cellular_component											owl:Class	
GO:0018290	biolink:NamedThing	iron and molybdenum incorporation into iron-molybdenum-sulfur cluster via L-cysteinyl homocitryl molybdenum-heptairon-nonasulfide	The incorporation of iron and molybdenum into a Mo-7Fe-8S iron-molybdenum-sulfur cluster via L-cysteinyl homocitryl molybdenum-heptairon-nonasulfide, found in nitrogenase.	tmpzr1t_l9r_go_relaxed.owl	iron and molybdenum incorporation into iron-molybdenum-sulphur cluster via L-cysteinyl homocitryl molybdenum-heptairon-nonasulphide				RESID:AA0141									biological_process											owl:Class	
GO:0031038	biolink:NamedThing	myosin II filament organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a bipolar filament composed of myosin II molecules.	tmpzr1t_l9r_go_relaxed.owl	myosin II filament assembly or disassembly|myosin II polymerization or depolymerization|myosin II filament organisation													biological_process											owl:Class	
GO:0045620	biolink:NamedThing	negative regulation of lymphocyte differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of lymphocyte differentiation.	tmpzr1t_l9r_go_relaxed.owl	inhibition of lymphocyte differentiation|down regulation of lymphocyte differentiation|negative regulation of lymphocyte development|down-regulation of lymphocyte differentiation|downregulation of lymphocyte differentiation					Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.								biological_process											owl:Class	
GO:0102751	biolink:NamedThing	UDP-alpha-D-glucose:glucosyl-glycogenin alpha-D-glucosyltransferase activity	Catalysis of the reaction: UDP-alpha-D-glucose + a glucosyl-glycogenin = (1,4-alpha-D-glucosyl)n-glucosyl glucogenin + UDP + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-7667|EC:2.4.1.186|RHEA:56560									molecular_function											owl:Class	
GO:0001573	biolink:NamedThing	ganglioside metabolic process	The chemical reactions and pathways involving ceramide oligosaccharides carrying in addition to other sugar residues, one or more sialic acid residues.	tmpzr1t_l9r_go_relaxed.owl	ganglioside metabolism													biological_process											owl:Class	
GO:0022601	biolink:NamedThing	menstrual cycle phase	The progression of physiological phases, occurring in the endometrium during the menstrual cycle that recur at regular intervals during the reproductive years. The menstrual cycle is an ovulation cycle where the endometrium is shed if pregnancy does not occur.	tmpzr1t_l9r_go_relaxed.owl						Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase. To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).								biological_process											owl:Class	
GO:1903787	biolink:NamedThing	negative regulation of glutathione biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of glutathione biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	downregulation of glutathione anabolism|downregulation of glutathione synthesis|negative regulation of glutathione anabolism|inhibition of glutathione biosynthetic process|downregulation of glutathione biosynthesis|down-regulation of glutathione anabolism|negative regulation of glutathione formation|inhibition of glutathione synthesis|down regulation of glutathione formation|inhibition of glutathione biosynthesis|down-regulation of glutathione biosynthesis|down regulation of glutathione anabolism|down-regulation of glutathione synthesis|down-regulation of glutathione biosynthetic process|downregulation of glutathione biosynthetic process|down regulation of glutathione synthesis|negative regulation of glutathione biosynthesis|downregulation of glutathione formation|down regulation of glutathione biosynthetic process|inhibition of glutathione anabolism|down regulation of glutathione biosynthesis|inhibition of glutathione formation|down-regulation of glutathione formation|negative regulation of glutathione synthesis							bf	2015-01-08T17:14:59Z					biological_process											owl:Class	
GO:0080183	biolink:NamedThing	response to photooxidative stress	Any process that results in a change in state or activity of a cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as the result of a photooxidative stress, the light-dependent generation of active oxygen species. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism.	tmpzr1t_l9r_go_relaxed.owl								dhl	2011-08-10T04:26:11Z					biological_process											owl:Class	
GO:0035551	biolink:NamedThing	protein initiator methionine removal involved in protein maturation	Removal of the initiating methionine or formylmethionine residue from a protein that contributes to protein maturation, the attainment of the full functional capacity of a protein.	tmpzr1t_l9r_go_relaxed.owl								bf	2010-05-13T04:29:05Z					biological_process											owl:Class	
GO:0070084	biolink:NamedThing	protein initiator methionine removal	The protein modification process in which the translation-initiating methionine or formylmethionine residue is removed from a protein.	tmpzr1t_l9r_go_relaxed.owl	removal of initiator methionine from protein													biological_process											owl:Class	
GO:0033951	biolink:NamedThing	oligosaccharide reducing-end xylanase activity	Catalysis of the hydrolysis of 1,4-beta-D-xylose residues from the reducing end of oligosaccharides.	tmpzr1t_l9r_go_relaxed.owl	reducing end xylose-releasing exo-oligoxylanase activity|Rex|beta-D-xylopyranosyl-(1->4)-beta-D-xylopyranosyl-(1->4)-beta-D-xylopyranose reducing-end xylanase activity				EC:3.2.1.156|MetaCyc:3.2.1.156-RXN									molecular_function											owl:Class	
GO:0003950	biolink:NamedThing	NAD+ ADP-ribosyltransferase activity	Catalysis of the reaction: NAD+ + (ADP-D-ribosyl)(n)-acceptor = nicotinamide + (ADP-D-ribosyl)(n+1)-acceptor.	tmpzr1t_l9r_go_relaxed.owl	ADP-ribosyltransferase (polymerizing) activity|poly(ADP-ribose) synthase activity|poly(ADP-ribose)polymerase activity|NAD ADP-ribosyltransferase activity|NAD+:poly(adenine-diphosphate-D-ribosyl)-acceptor ADP-D-ribosyl-transferase activity|poly(ADP-ribose) synthetase activity|poly(adenosine diphosphate ribose) polymerase activity				MetaCyc:NAD+-ADP-RIBOSYLTRANSFERASE-RXN|Reactome:R-HSA-8938073|Reactome:R-HSA-8948800|Reactome:R-HSA-5651723|Reactome:R-HSA-2187325|Reactome:R-HSA-9694773|Reactome:R-HSA-5688276|Reactome:R-HSA-9686061|Reactome:R-HSA-5687653|EC:2.4.2.30|Reactome:R-HSA-3640858									molecular_function											owl:Class	
GO:1904217	biolink:NamedThing	regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity	Any process that modulates the frequency, rate or extent of CDP-diacylglycerol-serine O-phosphatidyltransferase activity.	tmpzr1t_l9r_go_relaxed.owl	regulation of phosphatidylserine synthetase activity|regulation of serine exchange enzyme|regulation of CDP-diacylglycerol-L-serine O-phosphatidyltransferase activity|regulation of CDP-diglyceride-L-serine phosphatidyltransferase activity|regulation of CDP-diglycerine-serine O-phosphatidyltransferase activity|regulation of cytidine diphosphoglyceride-serine O-phosphatidyltransferase activity|regulation of CDP-diglyceride:serine phosphatidyltransferase activity|regulation of phosphatidylserine synthase activity|regulation of PS synthase activity|regulation of cytidine 5'-diphospho-1,2-diacyl-sn-glycerol (CDPdiglyceride):L-serine O-phosphatidyltransferase activity|regulation of CDPdiglyceride-serine O-phosphatidyltransferase activity|regulation of CDP-diacylglycerol:L-serine 3-O-phosphatidyltransferase activity|regulation of CDPdiacylglycerol-serine O-phosphatidyltransferase activity|regulation of cytidine 5'-diphospho-1,2-diacyl-sn-glycerol:L-serine O-phosphatidyltransferase activity					Serinc proteins form a complex with serine and sphingolipid biosynthesis enzymes and regulates their activity through regulation of availability of the substrate		rl	2015-05-15T08:18:23Z					biological_process											owl:Class	
GO:0030634	biolink:NamedThing	carbon fixation by acetyl-CoA pathway	A pathway of carbon dioxide fixation in which one molecule of acetyl-CoA is completely synthesized from two molecules of carbon dioxide (CO2).	tmpzr1t_l9r_go_relaxed.owl	Ljungdahl-Wood pathway|reductive acetyl CoA pathway|acetyl CoA pathway				Wikipedia:Wood-Ljungdahl_pathway|MetaCyc:CODH-PWY									biological_process											owl:Class	
GO:0006085	biolink:NamedThing	acetyl-CoA biosynthetic process	The chemical reactions and pathways resulting in the formation of acetyl-CoA, a derivative of coenzyme A in which the sulfhydryl group is acetylated.	tmpzr1t_l9r_go_relaxed.owl	acetyl-CoA synthesis|acetyl-CoA biosynthesis|acetyl-CoA formation|acetyl-CoA anabolism				MetaCyc:PWY-5173									biological_process											owl:Class	
GO:0010714	biolink:NamedThing	positive regulation of collagen metabolic process	Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the metabolism of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of collagen metabolism													biological_process											owl:Class	
GO:0102383	biolink:NamedThing	steviol 19-O glucosyltransferase activity	Catalysis of the reaction: steviol + UDP-alpha-D-glucose <=> 19-O-beta-glucopyranosyl-steviol + UDP + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-13520									molecular_function											owl:Class	
GO:0070919	biolink:NamedThing	production of siRNA involved in gene silencing by small RNA	Cleavage of double-stranded RNA to form small interfering RNA molecules (siRNAs) of 21-23 nucleotides, in the context of gene silencing by small RNA.	tmpzr1t_l9r_go_relaxed.owl	chromatin silencing by small RNA, production of siRNA|production of guide RNAs involved in chromatin silencing by small RNA|production of siRNA involved in chromatin silencing by small RNA|chromatin silencing by small RNA, production of guide RNAs	https://github.com/geneontology/go-ontology/issues/22058						mah	2009-09-11T03:39:18Z					biological_process											owl:Class	
GO:0009937	biolink:NamedThing	regulation of gibberellic acid mediated signaling pathway	Any process that modulates the frequency, rate or extent of gibberellic acid mediated signaling.	tmpzr1t_l9r_go_relaxed.owl	regulation of gibberellic acid mediated signalling													biological_process											owl:Class	
GO:0102856	biolink:NamedThing	1-18:2-2-18:2-sn-glycerol-3-phosphocholine desaturase activity	Catalysis of the reaction: 1-18:2-2-18:2-sn-glycerol-3-phosphocholine + O2 + a reduced electron acceptor <=> 1-18:3-2-18:2-phosphatidylcholine + 2 H2O + an oxidized electron acceptor.	tmpzr1t_l9r_go_relaxed.owl					EC:1.14.19.25|MetaCyc:RXN-8323									molecular_function											owl:Class	
GO:0046118	biolink:NamedThing	7-methylguanosine biosynthetic process	The chemical reactions and pathways resulting in the formation of 7-methylguanosine, a modified nucleoside that forms a cap at the 5'-terminus of eukaryotic mRNA.	tmpzr1t_l9r_go_relaxed.owl	7-methylguanosine formation|7-methylguanosine biosynthesis|7-methylguanosine synthesis|7-methylguanosine anabolism													biological_process											owl:Class	
GO:0050098	biolink:NamedThing	methylguanidinase activity	Catalysis of the reaction: H(2)O + methylguanidine = methylammonium + urea.	tmpzr1t_l9r_go_relaxed.owl	methylguanidine hydrolase activity|methylguanidine amidinohydrolase activity				KEGG_REACTION:R01589|RHEA:11764|MetaCyc:METHYLGUANIDINASE-RXN|EC:3.5.3.16									molecular_function											owl:Class	
GO:0044528	biolink:NamedThing	regulation of mitochondrial mRNA stability	Any process that modulates the propensity of mitochondrial mRNA molecules to degradation. Includes processes that both stabilize and destabilize mitochondrial mRNAs.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-03-15T03:20:10Z					biological_process											owl:Class	
GO:0072135	biolink:NamedThing	kidney mesenchymal cell proliferation	The multiplication or reproduction of cells, resulting in the expansion of a mesenchymal cell population in the kidney.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-02-22T02:33:10Z					biological_process											owl:Class	
GO:0047943	biolink:NamedThing	glutamate-methylamine ligase activity	Catalysis of the reaction: L-glutamate + ATP + methylammonium = N(5)-methyl-L-glutamine + ADP + 2 H(+) + phosphate.	tmpzr1t_l9r_go_relaxed.owl	gamma-glutamylmethylamide synthetase activity|L-glutamate:methylamine ligase (ADP-forming)				EC:6.3.4.12|MetaCyc:GLUTAMATE--METHYLAMINE-LIGASE-RXN|RHEA:17117|KEGG_REACTION:R01585									molecular_function											owl:Class	
GO:0102617	biolink:NamedThing	oryzalexin C synthase (oryzalexin B dependent) activity	Catalysis of the reaction: oryzalexin B + NAD(P) <=> oryzalexin C + H+ + NAD(P)H.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-15465									molecular_function											owl:Class	
GO:0060686	biolink:NamedThing	negative regulation of prostatic bud formation	Any process that decreases the rate, frequency, or extent of prostatic bud formation, the morphogenetic process in which a region of the fetal urogenital sinus epithelium is specified to become the prostate, resulting in prostate bud outgrowth.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-06-05T12:35:25Z					biological_process											owl:Class	
GO:0048109	biolink:NamedThing	peptide cross-linking via 2-amino-3-isothiazolidinone-L-serine	The chemical reactions and pathways resulting in the formation of a peptidyl cysteine-peptidyl serine cross-link through a process of forming first an intermediate cysteine sulfenic acid by peroxide oxidation, followed by condensation with the alpha-amido of the following serine residue and the release of water.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0344									biological_process											owl:Class	
GO:0098674	biolink:NamedThing	extrinsic component of neuronal dense core vesicle membrane	The component of the neuronal dense core vesicle membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.	tmpzr1t_l9r_go_relaxed.owl								dos	2017-01-17T16:20:56Z					cellular_component											owl:Class	
GO:0010589	biolink:NamedThing	leaf proximal/distal pattern formation	The regionalization process within a leaf by which specific areas of cell differentiation are determined along a proximal/distal axis.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0006046	biolink:NamedThing	N-acetylglucosamine catabolic process	The chemical reactions and pathways resulting in the breakdown of N-acetylglucosamine. The D isomer is a common structural unit of glycoproteins in plants, bacteria and animals; it is often the terminal sugar of an oligosaccharide group of a glycoprotein.	tmpzr1t_l9r_go_relaxed.owl	N-acetylglucosamine breakdown|N-acetylglucosamine degradation|N-acetylglucosamine catabolism													biological_process											owl:Class	
GO:0006844	biolink:NamedThing	acyl carnitine transport	The directed movement of acyl carnitine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Acyl carnitine is the condensation product of a carboxylic acid and carnitine and is the transport form for a fatty acid crossing the mitochondrial membrane.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0060951	biolink:NamedThing	neural crest-derived cardiac glial cell differentiation	The process in which a neural crest cell acquires the specialized features of a glial cell of the heart.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-09-29T03:08:06Z					biological_process											owl:Class	
GO:0102049	biolink:NamedThing	indole-3-acetyl-methionine synthetase activity	Catalysis of the reaction: indole-3-acetate + L-methionine + ATP(4-) <=> H+ + indole-3-acetyl-methionine + AMP(2-) + diphosphoric acid.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-10431									molecular_function											owl:Class	
GO:0097284	biolink:NamedThing	hepatocyte apoptotic process	Any apoptotic process in a hepatocyte, the main structural component of the liver.	tmpzr1t_l9r_go_relaxed.owl	hepatocyte apoptosis							pr	2012-03-29T10:23:21Z					biological_process											owl:Class	
GO:0008039	biolink:NamedThing	synaptic target recognition	The process in which a neuronal cell in a multicellular organism interprets signals produced by potential target cells, with which it may form synapses.	tmpzr1t_l9r_go_relaxed.owl	neuronal targeting													biological_process											owl:Class	
GO:0034231	biolink:NamedThing	islet amyloid polypeptide processing	The formation of mature islet amyloid polypeptide (IAPP) by posttranslational processing of pro-islet amyloid polypeptide (pro-IAPP).	tmpzr1t_l9r_go_relaxed.owl	islet amyloid peptide processing|IAPP formation|IAPP processing|islet amyloid polypeptide formation|islet amyloid peptide formation													biological_process											owl:Class	
GO:0071913	biolink:NamedThing	citrate secondary active transmembrane transporter activity	Enables the transfer of citrate from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters.	tmpzr1t_l9r_go_relaxed.owl	citrate carrier activity							mah	2010-09-22T02:18:54Z					molecular_function											owl:Class	
GO:1903539	biolink:NamedThing	protein localization to postsynaptic membrane	A process in which a protein is transported to, or maintained in, a location within a postsynaptic membrane.	tmpzr1t_l9r_go_relaxed.owl	protein localisation in postsynaptic membrane|protein localization in postsynaptic membrane|protein localisation to postsynaptic membrane							kmv	2014-10-10T11:23:53Z					biological_process											owl:Class	
GO:0048903	biolink:NamedThing	anterior lateral line neuromast hair cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of an anterior lateral line neuromast hair cell. Neuromast hair cells are the sensory receptors of the neuromast and are located in a portion of the neuromast called the sensory strip. Each hair cell of the neuromast is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. There are approximately seven hair cells within each neuromast, with each hair cell innervated by afferent and efferent neurons.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0002814	biolink:NamedThing	negative regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria	Any process that stops, prevents, or reduces the frequency, rate, or extent of biosynthesis of antibacterial peptides active against Gram-negative bacteria.	tmpzr1t_l9r_go_relaxed.owl	downregulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria|inhibition of biosynthetic process of antibacterial peptides active against Gram-negative bacteria|down regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria|down-regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria													biological_process											owl:Class	
GO:0002813	biolink:NamedThing	regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria	Any process that modulates the frequency, rate, or extent of biosynthesis of antibacterial peptides active against Gram-negative bacteria.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0010932	biolink:NamedThing	regulation of macrophage tolerance induction	Any process that modulates the frequency, rate, or extent of macrophage tolerance induction.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0031998	biolink:NamedThing	regulation of fatty acid beta-oxidation	Any process that modulates the frequency, rate or extent of fatty acid bbeta-oxidation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0042913	biolink:NamedThing	group A colicin transmembrane transporter activity	Enables the transfer of group A colicins (colicins E1, E2, E3, A, K, and N) from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0042912	biolink:NamedThing	colicin transmembrane transporter activity	Enables the transfer of a colicin from one side of a membrane to the other. Colicins are a group of antibiotics produced by E. coli and related species that are encoded by a group of naturally occurring plasmids, e.g. Col E1.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0097745	biolink:NamedThing	mitochondrial tRNA 5'-end processing	The process in which the 5' end of a pre-tRNA molecule is converted to that of a mature tRNA in the mitochondrion.	tmpzr1t_l9r_go_relaxed.owl								pr	2016-11-08T10:50:51Z					biological_process											owl:Class	
GO:1905671	biolink:NamedThing	regulation of lysosome organization	Any process that modulates the frequency, rate or extent of lysosome organization.	tmpzr1t_l9r_go_relaxed.owl	regulation of lysosome organisation|regulation of lysosome organization and biogenesis							sl	2016-11-11T22:01:04Z					biological_process											owl:Class	
GO:0048387	biolink:NamedThing	negative regulation of retinoic acid receptor signaling pathway	Any process that stops, prevents, or reduces the frequency, rate or extent of retinoic acid receptor signaling pathway activity.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of retinoic acid receptor signaling pathway|inhibition of retinoic acid receptor signaling pathway|negative regulation of RAR signalling pathway|negative regulation of retinoic acid receptor signalling pathway|down regulation of retinoic acid receptor signaling pathway|downregulation of retinoic acid receptor signaling pathway|negative regulation of RAR signaling pathway													biological_process											owl:Class	
GO:1903776	biolink:NamedThing	regulation of double-strand break repair via single-strand annealing, removal of nonhomologous ends	Any process that modulates the frequency, rate or extent of double-strand break repair via single-strand annealing, removal of nonhomologous ends.	tmpzr1t_l9r_go_relaxed.owl								al	2015-01-06T17:08:24Z					biological_process											owl:Class	
GO:0070426	biolink:NamedThing	positive regulation of nucleotide-binding oligomerization domain containing signaling pathway	Any process that activates or increases the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing (NOD) pathway.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of nucleotide-binding oligomerization domain containing signalling pathway|positive regulation of NOD signaling pathway													biological_process											owl:Class	
GO:0090566	biolink:NamedThing	protein-phosphocysteine-N,N'-diacetylchitobiose phosphotransferase system transporter activity	Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein S-phosphocysteine + N,N'-diacetylchitobiose(out) = protein cysteine + N,N'-diacetylchitobiose phosphate(in).	tmpzr1t_l9r_go_relaxed.owl								tb	2014-04-08T15:08:43Z					molecular_function											owl:Class	
GO:0034374	biolink:NamedThing	low-density lipoprotein particle remodeling	The acquisition, loss or modification of a protein or lipid within a low-density lipoprotein particle, including the hydrolysis of triglyceride by hepatic lipase, with the subsequent loss of free fatty acid, and the transfer of cholesterol esters from LDL to a triglyceride-rich lipoprotein particle by cholesteryl ester transfer protein (CETP), with the simultaneous transfer of triglyceride to LDL.	tmpzr1t_l9r_go_relaxed.owl	small dense low-density lipoprotein particle formation|LDL remodeling|small dense LDL formation													biological_process											owl:Class	
GO:0010120	biolink:NamedThing	camalexin biosynthetic process	The chemical reactions and pathways resulting in the formation of camalexin, an indole phytoalexin.	tmpzr1t_l9r_go_relaxed.owl	camalexin anabolism|camalexin synthesis|camalexin formation|camalexin biosynthesis				MetaCyc:CAMALEXIN-SYN									biological_process											owl:Class	
GO:0009700	biolink:NamedThing	indole phytoalexin biosynthetic process	The chemical reactions and pathways resulting in the formation of indole phytoalexins, any indole compound produced by plants as part of their defense response.	tmpzr1t_l9r_go_relaxed.owl	indole phytoalexin synthesis|indole phytoalexin biosynthesis|indole phytoalexin anabolism|indole phytoalexin formation													biological_process											owl:Class	
GO:0009447	biolink:NamedThing	putrescine catabolic process	The chemical reactions and pathways resulting in the breakdown of putrescine, 1,4-diaminobutane; putrescine is the metabolic precursor of spermidine and spermine.	tmpzr1t_l9r_go_relaxed.owl	putrescine degradation|putrescine breakdown|putrescine catabolism													biological_process											owl:Class	
GO:0009445	biolink:NamedThing	putrescine metabolic process	The chemical reactions and pathways involving putrescine, 1,4-diaminobutane; putrescine can be formed by decarboxylation of ornithine and is the metabolic precursor of spermidine and spermine.	tmpzr1t_l9r_go_relaxed.owl	putrescine metabolism													biological_process											owl:Class	
GO:0018598	biolink:NamedThing	hydroxymethylsilanetriol oxidase activity	Catalysis of the reaction: hydroxymethylsilanetriol + O2 + 2 H+ + 2 e- = 2 H2O + formylsilanetriol.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0641									molecular_function											owl:Class	
GO:0070993	biolink:NamedThing	translation preinitiation complex	A ribonucleoprotein complex that contains the small ribosomal subunit, a translation initiation ternary complex (i.e. an initiator tRNA, GTP, and an IF2 or eIF2 complex), and an mRNA.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-10-30T01:25:00Z					cellular_component											owl:Class	
GO:0006580	biolink:NamedThing	ethanolamine metabolic process	The chemical reactions and pathways involving ethanolamine (2-aminoethanol), an important water-soluble base of phospholipid (phosphatidylethanolamine).	tmpzr1t_l9r_go_relaxed.owl	ethanolamine metabolism											GO:0006645		biological_process											owl:Class	
GO:0036069	biolink:NamedThing	light-dependent bacteriochlorophyll biosynthetic process	The chemical reactions and pathways resulting in the formation of a bacteriochlorophyll, which occur in the presence of light. Bacteriochlorophylls are any of the chlorophylls of photosynthetic bacteria; they differ structurally from the chlorophylls of higher plants.	tmpzr1t_l9r_go_relaxed.owl	light-dependent bacteriochlorophyll synthesis|light-dependent bacteriochlorophyll biosynthesis|light-dependent bacteriochlorophyll formation|light dependent bacteriochlorophyll biosynthetic process|light-dependent bacteriochlorophyll anabolism							bf	2011-12-15T04:45:16Z					biological_process											owl:Class	
GO:0030494	biolink:NamedThing	bacteriochlorophyll biosynthetic process	The chemical reactions and pathways resulting in the formation of a bacteriochlorophyll, any of the chlorophylls of photosynthetic bacteria. They differ structurally from the chlorophylls of higher plants.	tmpzr1t_l9r_go_relaxed.owl	bacteriochlorophyll synthesis|bacteriochlorophyll anabolism|bacteriochlorophyll formation|bacteriochlorophyll biosynthesis													biological_process											owl:Class	
GO:0106277	biolink:NamedThing	biliverdin reductase (NADP+) activity	Catalysis of the reaction: bilirubin + NADP+ = biliverdin + NADPH + H+.	tmpzr1t_l9r_go_relaxed.owl					RHEA:15793|EC:1.3.1.24			hjd	2020-07-02T01:50:24Z					molecular_function											owl:Class	
GO:0004074	biolink:NamedThing	biliverdin reductase (NAD(P)+) activity	Catalysis of the reaction: bilirubin + NAD(P)+ = biliverdin + NAD(P)H + H+.	tmpzr1t_l9r_go_relaxed.owl	bilirubin:NAD(P)+ oxidoreductase activity				EC:1.3.1.24|MetaCyc:BILIVERDIN-REDUCTASE-RXN|Reactome:R-HSA-189384									molecular_function											owl:Class	
GO:0050297	biolink:NamedThing	stizolobate synthase activity	Catalysis of the reaction: 3,4-dihydroxy-L-phenylalanine + O2 = 4-(L-alanin-3-yl)-2-hydroxy-cis,cis-muconate 6-semialdehyde.	tmpzr1t_l9r_go_relaxed.owl	3,4-dihydroxy-L-phenylalanine:oxygen 4,5-oxidoreductase (recyclizing)				RHEA:21220|EC:1.13.11.29|MetaCyc:STIZOLOBATE-SYNTHASE-RXN									molecular_function											owl:Class	
GO:0061808	biolink:NamedThing	negative regulation of DNA recombination at centromere	Any process that stops, prevents, or reduces the frequency, rate or extent of genetic recombination at the centromere.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of centromeric recombination							dph	2016-11-10T15:24:50Z					biological_process											owl:Class	
GO:0061806	biolink:NamedThing	regulation of DNA recombination at centromere	Any process that modulates the frequency, rate or extent of DNA recombination within centromeric DNA.	tmpzr1t_l9r_go_relaxed.owl	regulation of centromeric recombination							dph	2016-11-10T15:17:11Z					biological_process											owl:Class	
GO:0002474	biolink:NamedThing	antigen processing and presentation of peptide antigen via MHC class I	The process in which an antigen-presenting cell expresses a peptide antigen on its cell surface in association with an MHC class I protein complex. Class I here refers to classical class I molecules.	tmpzr1t_l9r_go_relaxed.owl	peptide antigen processing and presentation via MHC class I													biological_process											owl:Class	
GO:0071880	biolink:NamedThing	adenylate cyclase-activating adrenergic receptor signaling pathway	The series of molecular signals generated as a consequence of an adrenergic receptor binding to its physiological ligand, where the pathway proceeds with activation of adenylyl cyclase and a subsequent increase in the concentration of cyclic AMP (cAMP).	tmpzr1t_l9r_go_relaxed.owl	activation of adenylate cyclase activity by adrenergic receptor signalling pathway|activation of adenylate cyclase activity by adrenergic receptor signaling pathway|adrenergic receptor, adenylyl cyclase activating pathway|adrenergic receptor, adenylate cyclase activating pathway							mah	2010-09-13T04:21:28Z					biological_process											owl:Class	
GO:0097532	biolink:NamedThing	stress response to acid chemical	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis caused by the chemical structure of the anion portion of a dissociated acid (rather than the acid acting as a proton donor). The acid chemical may be in gaseous, liquid or solid form.	tmpzr1t_l9r_go_relaxed.owl	response to acid stress|stress response to acid							pr	2013-11-12T13:04:15Z					biological_process											owl:Class	
GO:1904655	biolink:NamedThing	positive regulation of lung alveolus development	Any process that activates or increases the frequency, rate or extent of lung alveolus development.	tmpzr1t_l9r_go_relaxed.owl	activation of alveologenesis|up regulation of alveologenesis|up-regulation of alveologenesis|upregulation of alveolarization|up regulation of lung alveolus development|up-regulation of lung alveolus development|up regulation of alveolarization|upregulation of alveologenesis|positive regulation of alveolarization|up-regulation of alveolarization|positive regulation of alveologenesis|activation of lung alveolus development|activation of alveolarization|upregulation of lung alveolus development							sl	2015-09-03T22:44:56Z					biological_process											owl:Class	
GO:0038114	biolink:NamedThing	interleukin-21-mediated signaling pathway	A series of molecular signals initiated by the binding of interleukin-21 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.	tmpzr1t_l9r_go_relaxed.owl	IL-21-mediated signaling pathway|interleukin-21-mediated signalling pathway							bf	2012-03-22T10:21:01Z					biological_process											owl:Class	
GO:0052858	biolink:NamedThing	peptidyl-lysine acetyltransferase activity	Catalysis of the reaction: acetyl phosphate + peptidyl-L-lysine = phosphate + peptidyl-N6-acetyl-L-lysine.	tmpzr1t_l9r_go_relaxed.owl	acetyl-phosphate:peptidyl-L-lysine N6-acetyltransferase activity|peptidyl-lysine N6-acetyltransferase activity|peptidyl-lysine N-acetyltransferase activity, acting on acetyl phosphate as donor|peptidyl-lysine N(6)-acetyltransferase activity|acetyl-phosphate:peptidyl-L-lysine 6-N-acetyltransferase activity													molecular_function											owl:Class	
GO:1904000	biolink:NamedThing	positive regulation of eating behavior	Any process that activates or increases the frequency, rate or extent of eating behavior.	tmpzr1t_l9r_go_relaxed.owl	upregulation of eating behavior|upregulation of eating behaviour|up-regulation of eating behaviour|up regulation of eating behavior|activation of eating behavior|up regulation of eating behaviour|activation of eating behaviour|up-regulation of eating behavior|positive regulation of eating behaviour							sl	2015-03-05T20:40:35Z					biological_process											owl:Class	
GO:0035275	biolink:NamedThing	dibutyl phthalate binding	Binding to dibutyl phthalate, C(16)H(22)O(4).	tmpzr1t_l9r_go_relaxed.owl	phthalic acid dibutyl ester binding|DBP binding													molecular_function											owl:Class	
GO:1904420	biolink:NamedThing	positive regulation of telomeric loop formation	Any process that activates or increases the frequency, rate or extent of telomeric loop formation.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of telomeric loop formation|up regulation of t-loop formation|activation of telomeric loop formation|upregulation of t-loop formation|upregulation of telomeric loop formation|activation of t-loop formation|positive regulation of t-loop formation|up-regulation of t-loop biosynthesis|upregulation of t-loop biosynthesis|up regulation of telomeric loop formation|positive regulation of t-loop biosynthesis|up-regulation of t-loop formation|activation of t-loop biosynthesis|up regulation of t-loop biosynthesis							nc	2015-07-01T10:40:35Z					biological_process											owl:Class	
GO:0052753	biolink:NamedThing	propan-2-ol:coenzyme F420 oxidoreductase activity	Catalysis of the reaction: propan-2-ol + coenzyme F420 = acetone + reduced coenzyme F420.	tmpzr1t_l9r_go_relaxed.owl	F420-dependent propan-2-ol dehydrogenase activity|F420-dependent secondary alcohol dehydrogenase activity|isopropanol:coenzyme F420 oxidoreductase activity								2011-09-21T05:15:28Z					molecular_function											owl:Class	
GO:2000985	biolink:NamedThing	positive regulation of ATP citrate synthase activity	Any process that activates or increases the frequency, rate or extent of ATP citrate synthase activity.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of ATP:citrate oxaloacetate-lyase ((pro-S)-CH(2)COO(-)->acetyl-CoA) (ATP- dephosphorylating) activity|positive regulation of ATP:citrate oxaloacetate-lyase [(pro-S)-CH2COO-rightacetyl-CoA] (ATP-dephosphorylating)|positive regulation of acetyl-CoA:oxaloacetate C-acetyltransferase [(pro-S)-carboxymethyl-forming, ADP-phosphorylating]|positive regulation of ATP citrate (pro-S)-lyase activity|positive regulation of citrate-ATP lyase activity|positive regulation of citric cleavage enzyme activity|positive regulation of ATP-citrate (pro-S)-lyase activity|positive regulation of acetyl-CoA:oxaloacetate acetyltransferase (isomerizing; ADP- phosphorylating) activity|positive regulation of citrate cleavage enzyme activity|positive regulation of acetyl-CoA:oxaloacetate acetyltransferase (isomerizing; ADP-phosphorylating)|positive regulation of adenosine triphosphate citrate lyase activity|positive regulation of ATP-citrate (pro-S-)-lyase activity|positive regulation of ATP-citric lyase activity							vk	2011-08-04T03:15:31Z					biological_process											owl:Class	
GO:0044291	biolink:NamedThing	cell-cell contact zone	Extended zone of intimate apposition between two cells containing one or more types of intercellular junctions, e.g., the intercalated disk of muscle.	tmpzr1t_l9r_go_relaxed.owl	cell cell contact zone				NIF_Subcellular:sao1299635018			jl	2010-02-04T02:42:54Z					cellular_component											owl:Class	
GO:0048902	biolink:NamedThing	anterior lateral line neuromast deposition	The process in which a migrating neuromast primordium deposits clusters of undifferentiated cells (proneuromasts) along its migratory path in the developing anterior lateral line.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0075720	biolink:NamedThing	establishment of episomal latency	A process by which a virus establishes a latent state within its host as an episome, where the viral genome remains silent in the cytoplasm or nucleus as a distinct genetic entity.	tmpzr1t_l9r_go_relaxed.owl	establishment as a plasmid prophage|establishment of plasmid latency							jl	2009-11-26T03:57:44Z					biological_process											owl:Class	
GO:0019043	biolink:NamedThing	establishment of viral latency	A process by which a virus establishes a latent state within its host, either as an integrated provirus within the host genome or as an episome, where viral genome remains in the cytoplasm or nucleus as distinct objects.	tmpzr1t_l9r_go_relaxed.owl	lysogenic commitment|phage lysogeny											GO:0075601		biological_process											owl:Class	
GO:0048229	biolink:NamedThing	gametophyte development	The process whose specific outcome is the progression of the gametophyte over time, from its formation to the mature structure. The gametophyte is the gamete-producing individual or phase in the life cycle having alternation of generations. An example of this process is found in Arabidopsis thaliana.	tmpzr1t_l9r_go_relaxed.owl	gametogenesis													biological_process											owl:Class	
GO:1905129	biolink:NamedThing	endocannabinoid signaling pathway involved in trans-synaptic signaling	Any endocannabinoid signaling pathway that is involved in trans-synaptic signaling by endocannabinoid.	tmpzr1t_l9r_go_relaxed.owl	endocannabinoid signalling pathway involved in trans-synaptic signaling by endocannabinoid							dos	2016-04-12T10:45:13Z					biological_process											owl:Class	
GO:0071926	biolink:NamedThing	endocannabinoid signaling pathway	The series of molecular signals generated as a consequence of an endocannabinoid binding to a cell surface receptor. The pathway proceeds with the receptor transmitting the signal to a heterotrimeric G-protein complex and ends with regulation of a downstream cellular process, e.g. transcription. Endocannabinoids are small molecules derived from arachidonic acid, anandamide (arachidonoylethanolamide) and 2-arachidonoylglycerol.	tmpzr1t_l9r_go_relaxed.owl	endocannabinoid signalling pathway							mah	2010-09-28T11:52:03Z					biological_process											owl:Class	
GO:1900138	biolink:NamedThing	negative regulation of phospholipase A2 activity	Any process that stops, prevents or reduces the frequency, rate or extent of phospholipase A2 activity.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of secreted phospholipase A2 activity|inhibition of phosphatidylcholine 2-acylhydrolase activity|down regulation of phosphatidolipase activity|down-regulation of cytosolic phospholipase A2 activity|down-regulation of phosphatidase activity|downregulation of lecithinase A activity|down-regulation of phospholipase A|inhibition of phospholipase A2 activity|downregulation of phospholipase A2 activity|negative regulation of phosphatidylcholine 2-acylhydrolase activity|negative regulation of lecithinase A activity|inhibition of secreted phospholipase A2 activity|down regulation of phosphatidylcholine 2-acylhydrolase activity|inhibition of cytosolic phospholipase A2 activity|negative regulation of phosphatidase activity|down regulation of phosphatidase activity|inhibition of phospholipase A|down regulation of phospholipase A2 activity|downregulation of cytosolic phospholipase A2 activity|down regulation of secreted phospholipase A2 activity|negative regulation of phosphatidolipase activity|downregulation of phosphatidolipase activity|inhibition of phosphatidolipase activity|down-regulation of lecithinase A activity|negative regulation of cytosolic phospholipase A2 activity|down-regulation of phosphatidylcholine 2-acylhydrolase activity|down regulation of lecithinase A activity|inhibition of phosphatidase activity|down-regulation of phospholipase A2 activity|inhibition of lecithinase A activity|down regulation of phospholipase A|downregulation of secreted phospholipase A2 activity|down regulation of cytosolic phospholipase A2 activity|downregulation of phosphatidylcholine 2-acylhydrolase activity|downregulation of phosphatidase activity|negative regulation of phospholipase A|down-regulation of phosphatidolipase activity|down-regulation of secreted phospholipase A2 activity|downregulation of phospholipase A							rph	2012-03-01T09:18:24Z					biological_process											owl:Class	
GO:0061619	biolink:NamedThing	glycolytic process from mannose through fructose-6-phosphate	The chemical reactions and pathways resulting in the breakdown of mannose into pyruvate, occurring through a fructose-6-phosphate intermediate, with the concomitant production of ATP and NADH.	tmpzr1t_l9r_go_relaxed.owl								dph	2014-04-14T09:13:13Z					biological_process											owl:Class	
GO:0019309	biolink:NamedThing	mannose catabolic process	The chemical reactions and pathways resulting in the breakdown of mannose, the aldohexose manno-hexose, the C-2 epimer of glucose.	tmpzr1t_l9r_go_relaxed.owl	mannose breakdown|mannose catabolism|mannose degradation				MetaCyc:MANNCAT-PWY									biological_process											owl:Class	
GO:0106276	biolink:NamedThing	biliberdin reductase NAD+ activity	Catalysis of the reaction: bilirubin + NAD+ = biliverdin + NADH+ H+.	tmpzr1t_l9r_go_relaxed.owl					EC:1.3.1.24|RHEA:15797			hjd	2020-07-02T01:48:07Z					molecular_function											owl:Class	
GO:0047396	biolink:NamedThing	glycosylphosphatidylinositol diacylglycerol-lyase activity	Catalysis of the reaction: 6-(alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol = 1,2-diacyl-sn-glycerol + 6-(alpha-D-glucosaminyl)-1D-myo-inositol 1,2-cyclic phosphate.	tmpzr1t_l9r_go_relaxed.owl	glycosyl inositol phospholipid anchor-hydrolyzing enzyme activity|6-(alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol diacyl-sn-glycerol-lyase [6-(alpha-D-glucosaminyl)-1D-myo-inositol 1,2-cyclic phosphate-forming]|(glycosyl)phosphatidylinositol-specific phospholipase C activity|GPI-specific phospholipase C activity|variant-surface-glycoprotein phospholipase C activity|6-(alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol diacylglycerol-lyase (1,2-cyclic-phosphate-forming) activity|glycosylphosphatidylinositol-specific phospholipase C activity|VSG-lipase activity|GPI-PLC activity|glycosylphosphatidylinositol-phospholipase C activity				RHEA:14333|MetaCyc:3.1.4.47-RXN|EC:4.6.1.14									molecular_function											owl:Class	
GO:1902871	biolink:NamedThing	positive regulation of amacrine cell differentiation	Any process that activates or increases the frequency, rate or extent of amacrine cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	activation of amacrine neuron differentiation|up regulation of amacrine cell differentiation|up-regulation of amacrine neuron differentiation|upregulation of amacrine neuron differentiation|up-regulation of amacrine cell differentiation|activation of amacrine cell differentiation|positive regulation of amacrine neuron differentiation|up regulation of amacrine neuron differentiation|upregulation of amacrine cell differentiation							mr	2014-04-03T15:24:46Z					biological_process											owl:Class	
GO:0016513	biolink:NamedThing	core-binding factor complex	A heterodimeric transcription factor complex that contains an alpha subunit (Runx1, Runx2 or Runx3 in human) that binds DNA and a non-DNA-binding beta subunit (CBFbeta), and binds to a consensus sequence 5'-YGYGGTY-3' found in several enhancers and promoters; the beta subunit enhances the DNA binding of the alpha subunit.	tmpzr1t_l9r_go_relaxed.owl	PEPB2 complex|CBF complex|AML1 complex													cellular_component											owl:Class	
GO:0001755	biolink:NamedThing	neural crest cell migration	The characteristic movement of cells from the dorsal ridge of the neural tube to a variety of locations in a vertebrate embryo.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0032367	biolink:NamedThing	intracellular cholesterol transport	The directed movement of cholesterol, cholest-5-en-3-beta-ol, within cells.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1904294	biolink:NamedThing	positive regulation of ERAD pathway	Any process that activates or increases the frequency, rate or extent of ERAD pathway.	tmpzr1t_l9r_go_relaxed.owl	upregulation of ER-associated degradation pathway|up regulation of ER-associated degradation pathway|upregulation of ERAD pathway|activation of ER-associated degradation pathway|positive regulation of endoplasmic reticulum-associated degradation|activation of endoplasmic reticulum-associated degradation|up regulation of endoplasmic reticulum-associated protein degradation pathway|upregulation of endoplasmic reticulum-associated protein degradation pathway|activation of ERAD pathway|up regulation of ERAD pathway|up-regulation of endoplasmic reticulum-associated protein degradation pathway|up regulation of endoplasmic reticulum-associated degradation|up-regulation of ERAD pathway|activation of endoplasmic reticulum-associated protein degradation pathway|up-regulation of ER-associated degradation pathway|up-regulation of endoplasmic reticulum-associated degradation|positive regulation of ER-associated degradation pathway|positive regulation of endoplasmic reticulum-associated protein degradation pathway|upregulation of endoplasmic reticulum-associated degradation							bf	2015-06-09T14:44:39Z					biological_process											owl:Class	
GO:1905930	biolink:NamedThing	regulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching	Any process that modulates the frequency, rate or extent of vascular smooth muscle cell differentiation involved in phenotypic switching.	tmpzr1t_l9r_go_relaxed.owl	regulation of vascular smooth muscle cell differentiation involved in phenotypic dimorphism|regulation of vascular smooth muscle cell differentiation involved in phenotypic switching|regulation of VSMC differentiation involved in phenotypic dimorphism|regulation of VSMC differentiation involved in phenotypic switching|regulation of vascular associated smooth muscle cell differentiation involved in phenotypic dimorphism							rph	2017-02-09T09:20:59Z					biological_process											owl:Class	
GO:1905915	biolink:NamedThing	regulation of cell differentiation involved in phenotypic switching	Any process that modulates the frequency, rate or extent of cell differentiation involved in phenotypic switching.	tmpzr1t_l9r_go_relaxed.owl								rph	2017-02-08T12:23:14Z					biological_process											owl:Class	
GO:0098860	biolink:NamedThing	actin filament bundle of stereocilium	A bundle of hundreds of cross-linked actin filaments (an actin cable), that is the supporting structure of a stereocilium.  Filaments are oriented such that the the plus (barbed) ends are at the tip of the protrusion and are capped by a tip complex which bridges to the plasma membrane.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0004956	biolink:NamedThing	prostaglandin D receptor activity	Combining with prostaglandin D (PGD(2)) to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	PGD(2) receptor activity|PGD receptor activity													molecular_function											owl:Class	
GO:0004955	biolink:NamedThing	prostaglandin receptor activity	Combining with a prostaglandin (PG) to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1902157	biolink:NamedThing	regulation of response to G2 DNA damage checkpoint signaling	Any process that modulates the frequency, rate or extent of response to G2 DNA damage checkpoint signaling.	tmpzr1t_l9r_go_relaxed.owl	regulation of response to signal involved in G2/M transition DNA damage checkpoint|regulation of G2/M transition DNA damage checkpoint effector process							jl	2013-05-21T15:45:06Z					biological_process											owl:Class	
GO:0098574	biolink:NamedThing	cytoplasmic side of lysosomal membrane	The side (leaflet) of the lysosomal membrane that faces the cytoplasm.	tmpzr1t_l9r_go_relaxed.owl	external leaflet of lysosomal membrane|external side of lysosomal membrane													cellular_component											owl:Class	
GO:0050511	biolink:NamedThing	undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase activity	Catalysis of the reaction: Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol + UDP-N-acetyl-D-glucosamine = GlcNAc-(1,4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol + UDP.	tmpzr1t_l9r_go_relaxed.owl	UDP-N-acetyl-D-glucosamine:N-acetyl-alpha-D-muramyl(oyl-L-Ala- gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol beta-1,4-N-acetylglucosaminlytransferase activity|undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase activity|MurG transferase activity|UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase activity|undecaprenyldiphospho-muramoylpentapeptide b-N-acetylglucosaminyltransferase activity				RHEA:23192|MetaCyc:RXN-8976|EC:2.4.1.227	Note that EC classifies 'UDP-N-acetyl-D-glucosamine:N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine-diphosphoundecaprenol 4-beta-N-acetylglucosaminlytransferase activity ; GO:0051991' and 'undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase activity ; GO:0050511' under the same EC number, EC:2.4.1.227.								molecular_function											owl:Class	
GO:0034078	biolink:NamedThing	butanediol catabolic process	The chemical reactions and pathways resulting in the breakdown of butanediol; the biologically relevant isomer is 2,3-butanediol, CH3CH(OH)CH(OH)CH3.	tmpzr1t_l9r_go_relaxed.owl	butylene glycol catabolism|butanediol breakdown|butanediol utilization|butylene glycol catabolic process|butanediol catabolism|butanediol degradation													biological_process											owl:Class	
GO:0046325	biolink:NamedThing	negative regulation of glucose import	Any process that stops, prevents, or reduces the frequency, rate or extent of the import of the hexose monosaccharide glucose into a cell or organelle.	tmpzr1t_l9r_go_relaxed.owl	inhibition of glucose import|downregulation of glucose import|negative regulation of glucose uptake|down-regulation of glucose import|down regulation of glucose import													biological_process											owl:Class	
GO:0001607	biolink:NamedThing	neuromedin U receptor activity	Combining with neuromedin U to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	NMUR activity													molecular_function											owl:Class	
GO:0021534	biolink:NamedThing	cell proliferation in hindbrain	The multiplication or reproduction of cells, resulting in the expansion of a cell population in the hindbrain.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0071221	biolink:NamedThing	cellular response to bacterial lipopeptide	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bacterial lipopeptide stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-12-03T01:28:03Z					biological_process											owl:Class	
GO:1905715	biolink:NamedThing	regulation of cornification	Any process that modulates the frequency, rate or extent of cornification.	tmpzr1t_l9r_go_relaxed.owl								pga	2016-11-24T13:52:55Z					biological_process											owl:Class	
GO:0090216	biolink:NamedThing	positive regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity	Any process that increases the frequency, rate or extent of the catalysis of the reaction: ATP + 1-phosphatidyl-1D-myo-inositol 4-phosphate = ADP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate.	tmpzr1t_l9r_go_relaxed.owl								tb	2010-01-12T10:00:45Z					biological_process											owl:Class	
GO:0007190	biolink:NamedThing	activation of adenylate cyclase activity	Any process that initiates the activity of the inactive enzyme adenylate cyclase.	tmpzr1t_l9r_go_relaxed.owl	adenylate cyclase activator|adenylate cyclase activation|adenylyl cyclase activation													biological_process											owl:Class	
GO:0018711	biolink:NamedThing	benzoyl acetate-CoA thiolase activity	Catalysis of the reaction: benzoyl acetyl-CoA + CoA = acetyl-CoA + benzoyl-CoA.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0243|MetaCyc:RXN-1305									molecular_function											owl:Class	
GO:1901357	biolink:NamedThing	beta-D-galactofuranose catabolic process	The chemical reactions and pathways resulting in the breakdown of beta-D-galactofuranose.	tmpzr1t_l9r_go_relaxed.owl	beta-D-galactofuranose catabolism|beta-D-galactofuranose degradation|beta-D-galactofuranose breakdown							di	2012-09-13T22:19:30Z					biological_process											owl:Class	
GO:0047932	biolink:NamedThing	glucosamine N-acetyltransferase activity	Catalysis of the reaction: D-glucosamine + acetyl-CoA = N-acetyl-D-glucosamine + CoA + H(+).	tmpzr1t_l9r_go_relaxed.owl	glucosamine acetylase activity|acetyl-CoA:D-glucosamine N-acetyltransferase activity|glucosamine acetyltransferase activity				EC:2.3.1.3|KEGG_REACTION:R01204|MetaCyc:GLUCOSAMINE-N-ACETYLTRANSFERASE-RXN|RHEA:21332									molecular_function											owl:Class	
GO:0050951	biolink:NamedThing	sensory perception of temperature stimulus	The series of events required for an organism to receive a sensory temperature stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.	tmpzr1t_l9r_go_relaxed.owl	sensory perception of thermal stimulus													biological_process											owl:Class	
GO:2000274	biolink:NamedThing	regulation of epithelial cell migration, open tracheal system	Any process that modulates the frequency, rate or extent of epithelial cell migration, open tracheal system.	tmpzr1t_l9r_go_relaxed.owl	regulation of tracheal cell migration|regulation of tracheal epithelial cell migration							sart	2010-12-03T02:08:43Z					biological_process											owl:Class	
GO:0090349	biolink:NamedThing	negative regulation of cellular organohalogen metabolic process	Any process that decreases the rate, frequency or extent of the chemical reactions and pathways involving organohalogen compounds, as carried out by individual cells.	tmpzr1t_l9r_go_relaxed.owl								tb	2010-06-02T10:36:42Z					biological_process											owl:Class	
GO:0033744	biolink:NamedThing	L-methionine:thioredoxin-disulfide S-oxidoreductase activity	Catalysis of the reaction: L-methionine + thioredoxin disulfide + H2O = L-methionine (S)-S-oxide + thioredoxin.	tmpzr1t_l9r_go_relaxed.owl	L-methionine:oxidized-thioredoxin S-oxidoreductase activity|methyl sulfoxide reductase I and II activity|methionine-S-oxide reductase activity|fSMsr|methionine sulfoxide reductase activity|L-methionine-(S)-S-oxide reductase activity|acetylmethionine sulfoxide reductase activity|free-methionine (S)-S-oxide reductase activity				RHEA:19993|EC:1.8.4.13|KEGG_REACTION:R07606|MetaCyc:1.8.4.13-RXN							GO:0000317		molecular_function											owl:Class	
GO:0061478	biolink:NamedThing	response to platelet aggregation inhibitor	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a platelet aggregation inhibitor stimulus.	tmpzr1t_l9r_go_relaxed.owl								dph	2012-11-07T09:09:37Z					biological_process											owl:Class	
GO:0002589	biolink:NamedThing	regulation of antigen processing and presentation of peptide antigen via MHC class I	Any process that modulates the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class I.	tmpzr1t_l9r_go_relaxed.owl	regulation of peptide antigen processing and presentation via MHC class I													biological_process											owl:Class	
GO:0030511	biolink:NamedThing	positive regulation of transforming growth factor beta receptor signaling pathway	Any process that activates or increases the frequency, rate or extent of TGF-beta receptor signaling pathway activity.	tmpzr1t_l9r_go_relaxed.owl	activation of transforming growth factor beta receptor signaling pathway|positive regulation of transforming growth factor beta receptor signalling pathway|positive regulation of TGF-beta receptor signaling pathway|stimulation of transforming growth factor beta receptor signaling pathway|upregulation of transforming growth factor beta receptor signaling pathway|up-regulation of transforming growth factor beta receptor signaling pathway|up regulation of transforming growth factor beta receptor signaling pathway|positive regulation of TGFbeta receptor signaling pathway													biological_process											owl:Class	
GO:0045028	biolink:NamedThing	G protein-coupled purinergic nucleotide receptor activity	Combining with a purine nucleotide and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.	tmpzr1t_l9r_go_relaxed.owl	purinergic nucleotide receptor activity, G-protein coupled|P2Y receptor|purinergic nucleotide receptor activity, G protein coupled|G-protein coupled purinergic nucleotide receptor activity|G protein coupled purinergic nucleotide receptor activity|P2Y													molecular_function											owl:Class	
GO:0060832	biolink:NamedThing	oocyte animal/vegetal axis specification	The establishment, maintenance and elaboration of the animal/vegetal axis in the oocyte. The animal/vegetal axis of an oocyte is defined by the placement of the nucleus in the oocyte and can sometimes be identified by the asymmetric placement of other substances such as yolk in the oocyte. The pole of the egg that is closest to the nucleus defines the animal end, with the axis passing through the nucleus.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-08-11T03:11:06Z					biological_process											owl:Class	
GO:0102888	biolink:NamedThing	delta-cuprenene synthase activity	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate <=> delta-cuprenene + diphosphoric acid.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-8431									molecular_function											owl:Class	
GO:0045456	biolink:NamedThing	ecdysteroid biosynthetic process	The chemical reactions and pathways resulting in the formation of ecdysteroids, a group of polyhydroxylated ketosteroids which initiate post-embryonic development.	tmpzr1t_l9r_go_relaxed.owl	ecdysteroid formation|ecdysteroid anabolism|ecdysteroid biosynthesis|ecdysteroid synthesis													biological_process											owl:Class	
GO:0099044	biolink:NamedThing	vesicle tethering to endoplasmic reticulum	The initial, indirect interaction between a transport vesicle membrane and the membrane of the endoplasmic reticulum. This interaction is mediated by tethering factors (or complexes), which interact with both membranes.  Interaction can occur via direct binding  to membrane phospholipids or membrane proteins, or via binding to vesicle coat proteins. This process is distinct from and prior fusion.	tmpzr1t_l9r_go_relaxed.owl								tb	2013-01-08T15:07:50Z					biological_process											owl:Class	
GO:1900438	biolink:NamedThing	negative regulation of filamentous growth of a population of unicellular organisms in response to chemical stimulus	Any process that stops, prevents or reduces the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to chemical stimulus.	tmpzr1t_l9r_go_relaxed.owl	downregulation of filamentous growth of a population of unicellular organisms in response to chemical stimulus|down regulation of filamentous growth of a population of unicellular organisms in response to chemical stimulus|inhibition of filamentous growth of a population of unicellular organisms in response to chemical stimulus|down-regulation of filamentous growth of a population of unicellular organisms in response to chemical stimulus							di	2012-04-25T05:55:26Z					biological_process											owl:Class	
GO:0080086	biolink:NamedThing	stamen filament development	The process whose specific outcome is the progression of the filament over time, from its formation to the mature structure. Filament is the stalk of a stamen.	tmpzr1t_l9r_go_relaxed.owl	filament development							dhl	2009-04-22T03:12:03Z					biological_process											owl:Class	
GO:1900055	biolink:NamedThing	regulation of leaf senescence	Any process that modulates the frequency, rate or extent of leaf senescence.	tmpzr1t_l9r_go_relaxed.owl								tb	2012-01-24T11:51:24Z					biological_process											owl:Class	
GO:1900931	biolink:NamedThing	positive regulation of L-tyrosine import across plasma membrane	Any process that activates or increases the frequency, rate or extent of L-tyrosine import into the cell.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of L-tyrosine uptake|up regulation of L-tyrosine import|up-regulation of L-tyrosine uptake|positive regulation of L-tyrosine import|upregulation of L-tyrosine import|activation of L-tyrosine uptake|up-regulation of L-tyrosine import|upregulation of L-tyrosine uptake|activation of L-tyrosine import|up regulation of L-tyrosine uptake							al	2012-06-13T07:43:21Z					biological_process											owl:Class	
GO:0042418	biolink:NamedThing	epinephrine biosynthetic process	The chemical reactions and pathways resulting in the formation of epinephrine, a hormone produced by the medulla of the adrenal glands that increases heart activity, improves the power and prolongs the action of muscles, and increases the rate and depth of breathing. It is synthesized by the methylation of norepinephrine.	tmpzr1t_l9r_go_relaxed.owl	epinephrine synthesis|epinephrine biosynthesis|adrenaline biosynthesis|epinephrine formation|epinephrine anabolism|adrenaline biosynthetic process													biological_process											owl:Class	
GO:0042414	biolink:NamedThing	epinephrine metabolic process	The chemical reactions and pathways involving epinephrine, a hormone produced by the medulla of the adrenal glands that increases heart activity, improves the power and prolongs the action of muscles, and increases the rate and depth of breathing. It is synthesized by the methylation of norepinephrine.	tmpzr1t_l9r_go_relaxed.owl	epinephrine metabolism|adrenaline metabolism|adrenaline metabolic process													biological_process											owl:Class	
GO:0140430	biolink:NamedThing	positive regulation of chromosome passenger complex localization to kinetochore	Any process that activates or increases the frequency, rate or extent of a chromosome passenger complex localization to kinetochore.	tmpzr1t_l9r_go_relaxed.owl								pg	2020-02-19T05:19:45Z					biological_process											owl:Class	
GO:0050894	biolink:NamedThing	determination of affect	Any process in which an emotional response is associated with a particular sensory stimulation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0034489	biolink:NamedThing	neutral amino acid transmembrane export from vacuole	The directed movement of neutral amino acids out of the vacuole, across the vacuolar membrane.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0052032	biolink:NamedThing	modulation by symbiont of host inflammatory response	Any process in which a symbiont modulates the frequency, rate or extent of the inflammatory response of the host organism; the inflammatory response is the immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	modulation by organism of inflammatory response of other organism involved in symbiotic interaction											GO:0052256		biological_process											owl:Class	
GO:2000509	biolink:NamedThing	negative regulation of dendritic cell chemotaxis	Any process that stops, prevents or reduces the frequency, rate or extent of dendritic cell chemotaxis.	tmpzr1t_l9r_go_relaxed.owl								ebc	2011-03-22T10:21:45Z					biological_process											owl:Class	
GO:2000508	biolink:NamedThing	regulation of dendritic cell chemotaxis	Any process that modulates the frequency, rate or extent of dendritic cell chemotaxis.	tmpzr1t_l9r_go_relaxed.owl								ebc	2011-03-22T10:21:38Z					biological_process											owl:Class	
GO:0018145	biolink:NamedThing	protein-DNA covalent cross-linking via peptidyl-serine	The formation of a covalent cross-link between DNA and a peptidyl-serine residue by the formation of O-(phospho-5'-DNA)-L-serine.	tmpzr1t_l9r_go_relaxed.owl	DNA-protein covalent cross-linking via peptidyl-serine				RESID:AA0246									biological_process											owl:Class	
GO:1902735	biolink:NamedThing	negative regulation of receptor-mediated virion attachment to host cell	Any process that stops, prevents or reduces the frequency, rate or extent of receptor-mediated virion attachment to host cell.	tmpzr1t_l9r_go_relaxed.owl	downregulation of virion attachment, binding of host cell surface receptor|negative regulation of virion attachment, binding of host cell surface receptor|down-regulation of virion attachment, binding of host cell surface receptor|inhibition of virion attachment, binding of host cell surface receptor|inhibition of receptor-mediated virion attachment to host cell|down regulation of receptor-mediated virion attachment to host cell|down-regulation of receptor-mediated virion attachment to host cell|down regulation of virion attachment, binding of host cell surface receptor|downregulation of receptor-mediated virion attachment to host cell							als	2014-02-25T12:26:06Z					biological_process											owl:Class	
GO:1902604	biolink:NamedThing	p-aminobenzoyl-glutamate transmembrane transport	The directed movement of N-(4-aminobenzoyl)-L-glutamate across a membrane.	tmpzr1t_l9r_go_relaxed.owl	N-(4-aminobenzoyl)-L-glutamate transmembrane transport							pr	2013-12-20T11:09:20Z					biological_process											owl:Class	
GO:0004830	biolink:NamedThing	tryptophan-tRNA ligase activity	Catalysis of the reaction: ATP + L-tryptophan + tRNA(Trp) = AMP + diphosphate + L-tryptophanyl-tRNA(Trp).	tmpzr1t_l9r_go_relaxed.owl	tryptophanyl-tRNA synthase activity|tryptophan translase activity|tryptophanyl-transfer ribonucleic synthetase activity|tryptophanyl-transfer ribonucleate synthetase activity|tryptophanyl-transfer RNA synthetase activity|L-tryptophan:tRNATrp ligase (AMP-forming)|tryptophanyl ribonucleic synthetase activity|L-tryptophan-tRNATrp ligase (AMP-forming)|TrpRS activity|tryptophanyl-tRNA synthetase activity|L-tryptophan-tRNA(Trp) ligase (AMP-forming) activity|tryptophanyl-transfer ribonucleic acid synthetase activity				RHEA:24080|Reactome:R-HSA-379977|EC:6.1.1.2|Reactome:R-HSA-380222|MetaCyc:TRYPTOPHAN--TRNA-LIGASE-RXN									molecular_function											owl:Class	
GO:0042265	biolink:NamedThing	peptidyl-asparagine hydroxylation	The hydroxylation of peptidyl-asparagine to form peptidyl-hydroxyasparagine.	tmpzr1t_l9r_go_relaxed.owl	peptidyl-aspartic acid/asparagine hydroxylation													biological_process											owl:Class	
GO:0120315	biolink:NamedThing	positive regulation of oocyte karyosome formation	Any process that activates or increases the frequency, rate or extent of oocyte karyosome formation, the chromosome organization process in which meiotic chromosomes in the oocyte nucleus cluster together to form a compact spherical structure called the karyosome.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/21298						krc	2021-04-19T21:49:35Z					biological_process											owl:Class	
GO:0090437	biolink:NamedThing	socket cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a socket cell, a shoot epidermal cell that surrounds a trichome and provides its support.	tmpzr1t_l9r_go_relaxed.owl								tb	2012-07-31T17:01:28Z					biological_process											owl:Class	
GO:0019487	biolink:NamedThing	anaerobic acetylene catabolic process	The chemical reactions and pathways involving acetylene, a colorless, volatile, explosive gas, that occur in the absence of oxygen.	tmpzr1t_l9r_go_relaxed.owl	anaerobic acetylene catabolism|anaerobic ethyne catabolic process|anaerobic acetylene breakdown|anaerobic ethyne catabolism|anaerobic acetylene degradation				MetaCyc:P161-PWY									biological_process											owl:Class	
GO:0004117	biolink:NamedThing	calmodulin-dependent cyclic-nucleotide phosphodiesterase activity	Catalysis of the reaction: nucleoside 3',5'-cyclic phosphate + H2O = nucleoside 5'-phosphate; catalytic activity is regulated by calmodulin.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-111955									molecular_function											owl:Class	
GO:1900747	biolink:NamedThing	negative regulation of vascular endothelial growth factor signaling pathway	Any process that stops, prevents or reduces the frequency, rate or extent of vascular endothelial growth factor signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of vascular endothelial growth factor signalling pathway|down regulation of VEGF signaling|down-regulation of VEGF-activated signaling pathway|down regulation of vascular endothelial growth factor signaling pathway|downregulation of vascular endothelial growth factor signaling pathway|inhibition of vascular endothelial growth factor signalling pathway|inhibition of VEGF signaling|downregulation of VEGF signaling|down regulation of VEGF-activated signaling pathway|downregulation of VEGF-activated signaling pathway|negative regulation of VEGF-activated signaling pathway|inhibition of vascular endothelial growth factor signaling pathway|negative regulation of VEGF signaling|downregulation of vascular endothelial growth factor signalling pathway|inhibition of VEGF-activated signaling pathway|down-regulation of vascular endothelial growth factor signalling pathway|down regulation of vascular endothelial growth factor signalling pathway|down-regulation of VEGF signaling|down-regulation of vascular endothelial growth factor signaling pathway							pm	2012-05-29T08:28:29Z					biological_process											owl:Class	
GO:0072164	biolink:NamedThing	mesonephric tubule development	The progression of a mesonephric tubule over time, from its initial formation to the mature structure. A mesonephric tubule is an epithelial tube that is part of the mesonephros.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-02-26T01:45:58Z					biological_process											owl:Class	
GO:0046248	biolink:NamedThing	alpha-pinene biosynthetic process	The chemical reactions and pathways resulting in the formation of alpha-pinene, a monoterpene that may be a significant factor affecting bacterial activities in nature.	tmpzr1t_l9r_go_relaxed.owl	alpha-pinene formation|alpha-pinene anabolism|alpha-pinene synthesis|alpha-pinene biosynthesis													biological_process											owl:Class	
GO:0046528	biolink:NamedThing	imaginal disc fusion	The process following disc eversion whereby imaginal discs fuse with adjacent disc derivatives to form a continuous adult epidermis.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0048461	biolink:NamedThing	flower structural organization	The process that contributes to the act of creating the structural organization of the flower. This process pertains to the physical shaping of a rudimentary structure.	tmpzr1t_l9r_go_relaxed.owl	flower structural organisation											GO:0048412		biological_process											owl:Class	
GO:0034736	biolink:NamedThing	cholesterol O-acyltransferase activity	Catalysis of the reaction: acyl-CoA + cholesterol = a cholesterol ester + CoA.	tmpzr1t_l9r_go_relaxed.owl	acyl-CoA:cholesterol O-acyltransferase activity|cholesteryl ester synthetase activity|acylcoenzyme A:cholesterol O-acyltransferase activity|acyl coenzyme A-cholesterol-O-acyltransferase activity|cholesterol acyltransferase activity|cholesterol ester synthetase activity|ACAT activity|acyl-CoA:cholesterol acyltransferase activity				EC:2.3.1.26|Reactome:R-HSA-8876696|KEGG_REACTION:R01461|MetaCyc:STEROL-O-ACYLTRANSFERASE-RXN|RHEA:17729									molecular_function											owl:Class	
GO:1902459	biolink:NamedThing	positive regulation of stem cell population maintenance	Any process that activates or increases the frequency, rate or extent of stem cell population maintenance.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of stem cell maintenance|up-regulation of maintenance of pluripotency|upregulation of maintenance of pluripotency|positive regulation of maintenance of pluripotency|upregulation of stem cell maintenance|activation of stem cell maintenance|activation of maintenance of pluripotency|up regulation of stem cell maintenance|up regulation of maintenance of pluripotency							cjm	2013-10-16T22:27:47Z					biological_process											owl:Class	
GO:0110158	biolink:NamedThing	calpain complex	A calcium-dependent protease complex that processes its substrate by limited proteolysis rather than degrading it. In some cases limited proteolysis is required for the activation of its substrate.	tmpzr1t_l9r_go_relaxed.owl	M-calpain|mu-calpain							kmv	2019-07-15T18:30:51Z					cellular_component											owl:Class	
GO:0031682	biolink:NamedThing	G-protein gamma-subunit binding	Binding to a G-protein gamma subunit.	tmpzr1t_l9r_go_relaxed.owl	G-gamma protein subunit binding													molecular_function											owl:Class	
GO:0097524	biolink:NamedThing	sperm plasma membrane	A plasma membrane that is part of a sperm cell.	tmpzr1t_l9r_go_relaxed.owl								pr	2013-10-18T11:31:17Z					cellular_component											owl:Class	
GO:0047935	biolink:NamedThing	glucose 1-dehydrogenase (NADP+) activity	Catalysis of the reaction: D-glucose + NADP+ = D-glucono-1,5-lactone + NADPH.	tmpzr1t_l9r_go_relaxed.owl	nicotinamide adenine dinucleotide phosphate-linked aldohexose dehydrogenase activity|NADP-linked aldohexose dehydrogenase activity|NADP-dependent glucose dehydrogenase activity|D-glucose:NADP+ 1-oxidoreductase activity				MetaCyc:GLUCOSE-1-DEHYDROGENASE-NADP+-RXN|RHEA:14405|EC:1.1.1.119									molecular_function											owl:Class	
GO:0018305	biolink:NamedThing	iron incorporation into iron-sulfur cluster via tris-L-cysteinyl-L-serinyl tetrairon tetrasulfide	The incorporation of iron into a 4Fe-4S iron-sulfur cluster via tris-L-cysteinyl-L-serinyl tetrairon tetrasulfide.	tmpzr1t_l9r_go_relaxed.owl	iron incorporation into iron-sulphur cluster via tris-L-cysteinyl-L-serinyl tetrairon tetrasulphide				RESID:AA0288									biological_process											owl:Class	
GO:0003680	biolink:NamedThing	minor groove of adenine-thymine-rich DNA binding	Binding to a DNA structure formed by the minor groove of adenine-thymine-rich DNA regions. Examples of proteins having this function are AT-rich interaction domain (ARID)-containing proteins.	tmpzr1t_l9r_go_relaxed.owl	AT-rich DNA binding|AT DNA binding|AT binding	https://github.com/geneontology/go-ontology/issues/19695												molecular_function											owl:Class	
GO:0016363	biolink:NamedThing	nuclear matrix	The dense fibrillar network lying on the inner side of the nuclear membrane.	tmpzr1t_l9r_go_relaxed.owl	nucleoskeleton				Wikipedia:Nuclear_matrix									cellular_component											owl:Class	
GO:0071774	biolink:NamedThing	response to fibroblast growth factor	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fibroblast growth factor stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to FGF stimulus|response to fibroblast growth factor stimulus							mah	2010-08-31T11:06:32Z					biological_process											owl:Class	
GO:0052874	biolink:NamedThing	FMN reductase (NADH) activity	Catalysis of the reaction: FMNH2 + NAD+ = FMN + NADH + 2 H+.	tmpzr1t_l9r_go_relaxed.owl	FMNH2:NAD+ oxidoreductase activity|NADH:FMN oxidoreductase activity|NADH2:FMN oxidoreductase activity|NADH(2) dehydrogenase (FMN) activity|SsuE|NADH-FMN reductase activity|NADH(2):FMN oxidoreductase activity|flavin mononucleotide reductase activity|flavine mononucleotide reductase activity|NADH:flavin oxidoreductase activity|NADH2 dehydrogenase (FMN)|NADH dehydrogenase (FMN) activity|NADH-dependent FMN reductase activity				RHEA:21620|KEGG_REACTION:R05705|EC:1.5.1.39									molecular_function											owl:Class	
GO:1903223	biolink:NamedThing	positive regulation of oxidative stress-induced neuron death	Any process that activates or increases the frequency, rate or extent of oxidative stress-induced neuron death.	tmpzr1t_l9r_go_relaxed.owl	upregulation of neuronal cell death in response to oxidative stress|activation of oxidative stress-induced neuron death|activation of neuron death in response to oxidative stress|activation of neuronal cell death in response to oxidative stress|upregulation of oxidative stress-induced neuron death|sensitization of neuron to oxidative stress-induced cell death|upregulation of neuron death in response to oxidative stress|positive regulation of neuronal cell death in response to oxidative stress|up regulation of neuronal cell death in response to oxidative stress|up regulation of neuron death in response to oxidative stress|up regulation of oxidative stress-induced neuron death|up-regulation of oxidative stress-induced neuron death|up-regulation of neuron death in response to oxidative stress|positive regulation of neuron death in response to oxidative stress|up-regulation of neuronal cell death in response to oxidative stress							bf	2014-07-29T08:51:52Z					biological_process											owl:Class	
GO:0034812	biolink:NamedThing	9,10-dihydroxybenzo(a)pyrene dioxygenase activity	Catalysis of the reaction: 9,10-dihydroxybenzo(a)pyrene + O2 = cis-4-(8-hydroxypyren-7-yl)-2-oxobut-3-enoate.	tmpzr1t_l9r_go_relaxed.owl					EC:1.13.11.-|UM-BBD_reactionID:r1134									molecular_function											owl:Class	
GO:0047591	biolink:NamedThing	5-hydroxypentanoate CoA-transferase activity	Catalysis of the reaction: 5-hydroxypentanoate + acetyl-CoA = 5-hydroxy-pentanoyl-CoA + acetate.	tmpzr1t_l9r_go_relaxed.owl	5-hydroxyvalerate coenzyme A transferase activity|acetyl-CoA:5-hydroxypentanoate CoA-transferase activity|5-hydroxyvalerate CoA-transferase activity				MetaCyc:5-HYDROXYPENTANOATE-COA-TRANSFERASE-RXN|RHEA:23496|EC:2.8.3.14|KEGG_REACTION:R04057									molecular_function											owl:Class	
GO:0034247	biolink:NamedThing	snoRNA splicing	The process of removing sections of a primary snoRNA transcript to remove sequences not present in the mature form of the snoRNA and joining the remaining sections to form the mature form of the snoRNA.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:2000338	biolink:NamedThing	regulation of chemokine (C-X-C motif) ligand 1 production	Any process that modulates the frequency, rate or extent of chemokine (C-X-C motif) ligand 1 production.	tmpzr1t_l9r_go_relaxed.owl	regulation of keratinocyte derived chemokine production|regulation of KC production|regulation of SCYB1 production|regulation of CXCL1 production							mah	2011-02-01T10:46:27Z					biological_process											owl:Class	
GO:0072067	biolink:NamedThing	early distal convoluted tubule development	The process whose specific outcome is the progression of the early distal convoluted tubule over time, from its formation to the mature structure. The early distal convoluted tubule contains DCT cells and is vasopressin-insensitive.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-01-25T04:15:17Z					biological_process											owl:Class	
GO:0004663	biolink:NamedThing	Rab geranylgeranyltransferase activity	Catalysis of the reaction: 2 geranylgeranyl diphosphate + protein-cysteine = 2 S-geranylgeranyl-protein + 2 diphosphate. This reaction is the formation of two thioether linkages between the C-1 atom of the geranylgeranyl groups and two cysteine residues within the terminal sequence motifs XXCC, XCXC or CCXX. Known substrates include Ras-related GTPases of a single family and the Rab family.	tmpzr1t_l9r_go_relaxed.owl	geranylgeranyl-diphosphate,geranylgeranyl-diphosphate:protein-cysteine geranyltransferase activity|RabGGTase activity|protein geranylgeranyltransferase type II activity|GGTase-II activity|GGTaseII activity|Rab-protein geranylgeranyltransferase activity|type II protein geranyl-geranyltransferase activity				MetaCyc:2.5.1.60-RXN|MetaCyc:RXN-3701|EC:2.5.1.60									molecular_function											owl:Class	
GO:0048509	biolink:NamedThing	regulation of meristem development	Any process that modulates the frequency, rate or extent of meristem development, the biological process whose specific outcome is the progression of the meristem over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0106120	biolink:NamedThing	positive regulation of sterol biosynthetic process	Any process that activates or increases the frequency, rate or extent of a sterol biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl								hjd	2018-04-19T17:48:21Z					biological_process											owl:Class	
GO:1902228	biolink:NamedThing	positive regulation of macrophage colony-stimulating factor signaling pathway	Any process that activates or increases the frequency, rate or extent of macrophage colony-stimulating factor signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of macrophage colony-stimulating factor signaling pathway|activation of M-CSF signaling pathway|upregulation of M-CSF signaling pathway|activation of macrophage colony-stimulating factor signaling pathway|up regulation of macrophage colony-stimulating factor signaling pathway|positive regulation of macrophage colony-stimulating factor signalling pathway|upregulation of macrophage colony-stimulating factor signaling pathway|up regulation of M-CSF signaling pathway|positive regulation of M-CSF signaling pathway|upregulation of macrophage colony-stimulating factor signalling pathway|up-regulation of macrophage colony-stimulating factor signalling pathway|up-regulation of M-CSF signaling pathway|activation of macrophage colony-stimulating factor signalling pathway|up regulation of macrophage colony-stimulating factor signalling pathway							lb	2013-06-14T06:29:00Z					biological_process											owl:Class	
GO:0103106	biolink:NamedThing	brassinolide 23-O-glucosyltransferase activity	Catalysis of the reaction: brassinolide + UDP-alpha-D-glucose <=> brassinolide-23-O-glucoside + UDP + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXNQT-4397									molecular_function											owl:Class	
GO:1900394	biolink:NamedThing	regulation of kojic acid biosynthetic process	Any process that modulates the frequency, rate or extent of kojic acid biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one anabolism|regulation of C6H6O4 biosynthesis|regulation of C6H6O4 synthesis|regulation of kojic acid synthesis|regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one synthesis|regulation of kojic acid biosynthesis|regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one biosynthetic process|regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one formation|regulation of C6H6O4 formation|regulation of kojic acid formation|regulation of 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one biosynthesis|regulation of C6H6O4 biosynthetic process|regulation of C6H6O4 anabolism|regulation of kojic acid anabolism							di	2012-04-18T04:19:53Z					biological_process											owl:Class	
GO:0033041	biolink:NamedThing	sweet taste receptor activity	Combining with soluble sweet compounds to initiate a change in cell activity. These receptors are responsible for the sense of sweet taste.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0038122	biolink:NamedThing	C-C motif chemokine 5 receptor activity	Combining with the C-C motif chemokine 5 (CCL5) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	RANTES receptor activity|CCL5 receptor activity|small inducible cytokine A5 receptor activity							bf	2012-03-22T01:36:00Z					molecular_function											owl:Class	
GO:0106320	biolink:NamedThing	(R)-limonene 1,2-monooxygenase NADPH activity	Catalysis of the reaction: (4R)-limonene + NADPH + H+ + O2 = NADP+ + H2O + (4R)-limonene-1,2-epoxide.	tmpzr1t_l9r_go_relaxed.owl					EC:1.14.13.107|RHEA:26097			hjd	2020-09-23T15:20:57Z					molecular_function											owl:Class	
GO:0018635	biolink:NamedThing	(R)-limonene 1,2-monooxygenase activity	Catalysis of the reaction: (4R)-limonene + NAD(P)H + H+ + O2 = NAD(P)+ + H2O + (4R)-limonene-1,2-epoxide.	tmpzr1t_l9r_go_relaxed.owl	(+)-limonene,NAD(P)H:oxygen oxidoreductase activity|(+)-limonene 1,2-monooxygenase activity|(R)-limonene,NAD(P)H:oxygen oxidoreductase activity				UM-BBD_reactionID:r0733|KEGG_REACTION:R06398|KEGG_REACTION:R09393|MetaCyc:RXN-9407|EC:1.14.13.107									molecular_function											owl:Class	
GO:0034785	biolink:NamedThing	salicylate 5-hydroxylase activity	Catalysis of the reaction: salicylate + O2 + NAD(P)H + H+ = gentisate + H2O + NAD(P)+.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r1034|MetaCyc:RXN-10446|RHEA:35307|EC:1.14.13.172									molecular_function											owl:Class	
GO:0047519	biolink:NamedThing	quinate dehydrogenase (quinone) activity	Catalysis of the reaction: (-)-quinate + pyrroloquinoline-quinone = (-)-3-dehydroquinate + pyrroloquinoline-quinol.	tmpzr1t_l9r_go_relaxed.owl	quinate:quinone 3-oxidoreductase activity|NAD(P)-independent quinate dehydrogenase activity|quinate:pyrroloquinoline-quinone 5-oxidoreductase activity				RHEA:23672|EC:1.1.5.8|KEGG_REACTION:R01873|MetaCyc:1.1.99.25-RXN									molecular_function											owl:Class	
GO:2000896	biolink:NamedThing	amylopectin metabolic process	The chemical reactions and pathways involving an amylopectin.	tmpzr1t_l9r_go_relaxed.owl	Amylopectin metabolism							jl	2011-07-28T02:47:25Z					biological_process											owl:Class	
GO:0044016	biolink:NamedThing	histone acetyltransferase activity (H3-K4 specific)	Catalysis of the reaction: acetyl-CoA + histone H3 L-lysine (position 4) = CoA + histone H3 N6-acetyl-L-lysine (position 4).	tmpzr1t_l9r_go_relaxed.owl	histone lysine N-acetyltransferase activity (H3-K4 specific)													molecular_function											owl:Class	
GO:0044358	biolink:NamedThing	envenomation resulting in hemorrhagic damage to other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with vascular damage and hemorrhage in the bitten organism.	tmpzr1t_l9r_go_relaxed.owl								jl	2011-10-26T04:24:59Z					biological_process											owl:Class	
GO:0047327	biolink:NamedThing	glycerol-3-phosphate-glucose phosphotransferase activity	Catalysis of the reaction: sn-glycerol 3-phosphate + D-glucose = D-glucose 6-phosphate + glycerol.	tmpzr1t_l9r_go_relaxed.owl	sn-glycerol-3-phosphate:D-glucose 6-phosphotransferase activity				MetaCyc:2.7.1.142-RXN|KEGG_REACTION:R00850|EC:2.7.1.142|RHEA:21288									molecular_function											owl:Class	
GO:0014879	biolink:NamedThing	detection of electrical stimulus involved in regulation of muscle adaptation	The series of events by which an electrical stimulus is received and converted into a molecular signal. This occurs as part of the regulation of muscle adaptation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0014878	biolink:NamedThing	response to electrical stimulus involved in regulation of muscle adaptation	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electrical stimulus. This process occurs as part of the regulation of muscle adaptation.	tmpzr1t_l9r_go_relaxed.owl	response to electrical stimulus involved in regulation of muscle plasticity													biological_process											owl:Class	
GO:0004369	biolink:NamedThing	glycerol-3-phosphate oxidase activity	Catalysis of the reaction: sn-glycerol 3-phosphate + O(2) = glycerone phosphate + H(2)O(2).	tmpzr1t_l9r_go_relaxed.owl	L-alpha-glycerophosphate oxidase activity|glycerol phosphate oxidase activity|sn-glycerol-3-phosphate:oxygen 2-oxidoreductase activity|L-alpha-glycerol-3-phosphate oxidase activity|glycerol-1-phosphate oxidase activity|alpha-glycerophosphate oxidase activity				EC:1.1.3.21|RHEA:18369|MetaCyc:GLYCEROL-3-PHOSPHATE-OXIDASE-RXN|KEGG_REACTION:R00846									molecular_function											owl:Class	
GO:1901483	biolink:NamedThing	regulation of transcription factor catabolic process	Any process that modulates the frequency, rate or extent of transcription factor catabolic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of sequence-specific DNA binding transcription factor catabolic process|regulation of transcription factor catabolism|regulation of transcription factor degradation|regulation of proteasome-mediated transcription factor catabolism|regulation of transcription factor breakdown							bf	2012-10-08T09:03:18Z					biological_process											owl:Class	
GO:0034939	biolink:NamedThing	5-hydroxypyrrole-2-carboxylate tautomerase activity	Catalysis of the reaction: 5-hydroxypyrrole-2-carboxylate = 5-oxo-4,5-dihydropyrrole-2-carboxylate.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0969									molecular_function											owl:Class	
GO:0034524	biolink:NamedThing	2-hydroxyisophthalate decarboxylase activity	Catalysis of the reaction: 2-hydroxyisophthalic acid = salicylate + CO2.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0776									molecular_function											owl:Class	
GO:1903423	biolink:NamedThing	positive regulation of synaptic vesicle recycling	Any process that activates or increases the frequency, rate or extent of synaptic vesicle recycling.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of kiss-and-stay synaptic vesicle recycling|upregulation of kiss-and-run synaptic vesicle recycling|up-regulation of synaptic vesicle recycling|activation of synaptic vesicle recycling|activation of kiss-and-stay synaptic vesicle recycling|up regulation of synaptic vesicle recycling|activation of kiss-and-run synaptic vesicle recycling|positive regulation of kiss-and-stay synaptic vesicle recycling|positive regulation of kiss-and-run synaptic vesicle recycling|up regulation of kiss-and-stay synaptic vesicle recycling|up-regulation of kiss-and-run synaptic vesicle recycling|up regulation of kiss-and-run synaptic vesicle recycling|upregulation of synaptic vesicle recycling|upregulation of kiss-and-stay synaptic vesicle recycling					An example of this is mouse LRRK2 (Q5S006) in PMID:21307259 inferred from mutant phenotype		pad	2014-09-09T15:28:07Z					biological_process											owl:Class	
GO:0061161	biolink:NamedThing	positive regulation of establishment of bipolar cell polarity regulating cell shape	Any process that increases the rate, frequency or extent of the establishment of bipolar cell polarity that regulates the shape of a cell.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-06-23T09:26:45Z					biological_process											owl:Class	
GO:2000247	biolink:NamedThing	positive regulation of establishment or maintenance of bipolar cell polarity regulating cell shape	Any process that activates or increases the frequency, rate or extent of establishment or maintenance of bipolar cell polarity regulating cell shape.	tmpzr1t_l9r_go_relaxed.owl								vw	2010-11-11T11:39:34Z					biological_process											owl:Class	
GO:0061374	biolink:NamedThing	mammillothalamic axonal tract development	The progression of the mammillothalamic axonal tract, from its formation to the mature structure. The mammillothalamic tract is the collection of axons that connects the two major subdivisions of the diencephalon (hypothalamus and thalamus) and closes the diencephalic circuit.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-11-09T08:54:43Z					biological_process											owl:Class	
GO:0002620	biolink:NamedThing	negative regulation of non-professional antigen presenting cell antigen processing and presentation	Any process that stops, prevents, or reduces the frequency, rate, or extent of non-professional antigen presenting cell antigen processing and presentation.	tmpzr1t_l9r_go_relaxed.owl	inhibition of non-professional antigen presenting cell antigen processing and presentation|downregulation of non-professional antigen presenting cell antigen processing and presentation|down regulation of non-professional antigen presenting cell antigen processing and presentation|down-regulation of non-professional antigen presenting cell antigen processing and presentation													biological_process											owl:Class	
GO:0075029	biolink:NamedThing	formation of appressorium germ tube hook structure	The development of a swollen tip at the growing end of a symbiont spore which usually flattens against the host cell surface prior to appressorium formation.	tmpzr1t_l9r_go_relaxed.owl	formation of germ tube tip of symbiont on or near the exterior of host|symbiont germ tube hook structure formation on or near host|formation of symbiont germ tube hook structure on or near host|formation of symbiont germ tube hook structure for appressorium development													biological_process											owl:Class	
GO:1905941	biolink:NamedThing	positive regulation of gonad development	Any process that activates or increases the frequency, rate or extent of gonad development.	tmpzr1t_l9r_go_relaxed.owl	upregulation of gonad development|activation of gonad development|upregulation of gonadogenesis|positive regulation of gonadogenesis|up-regulation of gonadogenesis|up-regulation of gonad development|activation of gonadogenesis|up regulation of gonadogenesis|up regulation of gonad development							hbye	2017-02-09T17:02:08Z					biological_process											owl:Class	
GO:0009269	biolink:NamedThing	response to desiccation	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a desiccation stimulus, extreme dryness resulting from the prolonged deprivation of water.	tmpzr1t_l9r_go_relaxed.owl	desiccation tolerance													biological_process											owl:Class	
GO:0050176	biolink:NamedThing	phenylalanine N-acetyltransferase activity	Catalysis of the reaction: L-phenylalanine + acetyl-CoA = N-acetyl-L-phenylalanine + CoA + H(+).	tmpzr1t_l9r_go_relaxed.owl	acetyl-CoA-L-phenylalanine alpha-N-acetyltransferase activity|acetyl-CoA:L-phenylalanine N-acetyltransferase activity				RHEA:17801|KEGG_REACTION:R00693|EC:2.3.1.53|MetaCyc:PHENYLALANINE-N-ACETYLTRANSFERASE-RXN									molecular_function											owl:Class	
GO:0042251	biolink:NamedThing	maintenance of polarity of larval imaginal disc epithelium	The maintenance of an established polarized larval imaginal disc epithelium.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0000717	biolink:NamedThing	nucleotide-excision repair, DNA duplex unwinding	The unwinding, or local denaturation, of the DNA duplex to create a bubble around the site of the DNA damage.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0034279	biolink:NamedThing	syn-pimara-7,15-diene synthase activity	Catalysis of the reaction: 9-alpha-copalyl diphosphate = 9-beta-pimara-7,15-diene + diphosphate.	tmpzr1t_l9r_go_relaxed.owl	9alpha-copalyl-diphosphate diphosphate-lyase (9beta-pimara-7,15-diene-forming) activity				RHEA:25560|KEGG_REACTION:R09117|MetaCyc:RXN-4883|EC:4.2.3.35									molecular_function											owl:Class	
GO:0003777	biolink:NamedThing	microtubule motor activity	A motor activity that generates movement along a microtubule, driven by ATP hydrolysis.	tmpzr1t_l9r_go_relaxed.owl	dynein|ATP-dependent microtubule motor activity|kinesin|kinetochore motor activity|kinesin motor activity|dynein ATPase activity|axonemal motor activity	https://github.com/geneontology/go-ontology/issues/18664			Reactome:R-HSA-9610627|Reactome:R-HSA-177479|Reactome:R-HSA-265160	Consider also annotating to the molecular function term 'microtubule binding ; GO:0008017'.		vw	2016-04-04T10:59:42Z			GO:1990939		molecular_function											owl:Class	
GO:0140550	biolink:NamedThing	phosphatidylinositol-4,5-bisphosphate sensor activity	Binding to and responding, e.g. by conformational change, to changes in the cellular level of phosphatidylinositol-4,5-bisphosphate.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/20361						pg	2020-11-12T13:01:17Z					molecular_function											owl:Class	
GO:0090565	biolink:NamedThing	protein-phosphocysteine-mannitol phosphotransferase system transporter activity	Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein S-phosphocysteine + mannitol(out) = protein cysteine + mannitol phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.	tmpzr1t_l9r_go_relaxed.owl								tb	2014-04-08T15:03:08Z					molecular_function											owl:Class	
GO:1990406	biolink:NamedThing	CGRP receptor complex	A transmembrane, G protein-coupled signalling receptor complex recognized by calcitonin gene-related peptides (CGRP).	tmpzr1t_l9r_go_relaxed.owl	CGRP-R complex|calcitonin gene-related polypeptide receptor complex|Calcitonin-gene-related peptide receptor complex					An example of this is CALCRL in human (Q16602) in PMID:20826335 (inferred from direct assay).		bhm	2014-07-01T14:57:43Z					cellular_component											owl:Class	
GO:0019762	biolink:NamedThing	glucosinolate catabolic process	The chemical reactions and pathways resulting in the breakdown of glucosinolates, substituted thioglucosides found in rapeseed products and related cruciferae.	tmpzr1t_l9r_go_relaxed.owl	glucosinolate breakdown|glucosinolate degradation|glucosinolate catabolism				MetaCyc:PWY-5267									biological_process											owl:Class	
GO:0019759	biolink:NamedThing	glycosinolate catabolic process	The chemical reactions and pathways resulting in the breakdown of glycosinolates, substituted thioglycosides found in rapeseed products and related cruciferae.	tmpzr1t_l9r_go_relaxed.owl	glycosinolate catabolism|glycosinolate degradation|glycosinolate breakdown													biological_process											owl:Class	
GO:0047713	biolink:NamedThing	galactitol 2-dehydrogenase activity	Catalysis of the reaction: galactitol + NAD(+) = D-tagatose + H(+) + NADH.	tmpzr1t_l9r_go_relaxed.owl					EC:1.1.1.16|KEGG_REACTION:R02928|MetaCyc:GALACTITOL-2-DEHYDROGENASE-RXN|RHEA:20685									molecular_function											owl:Class	
GO:0071119	biolink:NamedThing	alpha7-beta1 integrin-nicotinamide riboside kinase complex	A protein complex that consists of an alpha7-beta1 integrin complex bound to nicotinamide riboside kinase 2 (also known as muscle integrin binding protein, MIBP).	tmpzr1t_l9r_go_relaxed.owl	ITGA7-ITGB1-ITGB1BP3 complex							mah	2009-11-13T02:20:44Z					cellular_component											owl:Class	
GO:0045226	biolink:NamedThing	extracellular polysaccharide biosynthetic process	The chemical reactions and pathways resulting in the formation of polysaccharides used in extracellular structures.	tmpzr1t_l9r_go_relaxed.owl	extracellular polysaccharide anabolism|extracellular polysaccharide biosynthesis|extracellular polysaccharide synthesis|extracellular polysaccharide formation													biological_process											owl:Class	
GO:0015661	biolink:NamedThing	L-lysine efflux transmembrane transporter activity	Enables the transfer of L-lysine from the inside of the cell to the outside of the cell across a membrane.	tmpzr1t_l9r_go_relaxed.owl	L-lysine exporter activity|L-lysine, 2,6-diaminohexanoic acid efflux transmembrane transporter activity													molecular_function											owl:Class	
GO:0080147	biolink:NamedThing	root hair cell development	The process whose specific outcome is the progression of a root hair cell over time, from its formation to the mature state.	tmpzr1t_l9r_go_relaxed.owl								dhl	2010-03-26T01:45:08Z					biological_process											owl:Class	
GO:0034281	biolink:NamedThing	ent-isokaurene synthase activity	Catalysis of the reaction: ent-copalyl diphosphate = ent-isokaurene + diphosphate.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0047715	biolink:NamedThing	hypotaurocyamine kinase activity	Catalysis of the reaction: ATP + hypotaurocyamine = N(omega)-phosphohypotaurocyamine + ADP + 2 H(+).	tmpzr1t_l9r_go_relaxed.owl	ATP:hypotaurocyamine N-phosphotransferase activity				MetaCyc:HYPOTAUROCYAMINE-KINASE-RXN|KEGG_REACTION:R03939|RHEA:24008|EC:2.7.3.6									molecular_function											owl:Class	
GO:0044658	biolink:NamedThing	pore formation in membrane of host by symbiont	The aggregation, arrangement and bonding together of a set of components by an organism to form a pore complex in a membrane of a host organism.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-08-01T13:14:42Z					biological_process											owl:Class	
GO:0034934	biolink:NamedThing	phenanthrene-4-carboxylate dioxygenase activity	Catalysis of the reaction: phenanthrene-4-carboxylate + 2 H+ + 2 e- + O2 = cis-3,4-phenanthrenedihydrodiol-4-carboxylate.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0939|EC:1.13.11.-									molecular_function											owl:Class	
GO:0062001	biolink:NamedThing	negative regulation of cardiac endothelial to mesenchymal transition	Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac endothelial to mesenchymal transition.	tmpzr1t_l9r_go_relaxed.owl								dph	2018-02-16T16:36:48Z					biological_process											owl:Class	
GO:0097289	biolink:NamedThing	alpha-ribazole metabolic process	The chemical reactions and pathways involving alpha-ribazole, the benzimidazole nucleoside in adenosyl cobalamin (vitamin B12).	tmpzr1t_l9r_go_relaxed.owl	alpha-ribazole metabolism							pr	2012-04-25T11:49:24Z					biological_process											owl:Class	
GO:0006673	biolink:NamedThing	inositol phosphoceramide metabolic process	The chemical reactions and pathways involving inositol phosphoceramides, any lipid with a phosphodiester bridge between an inositol residue and the ceramide group.	tmpzr1t_l9r_go_relaxed.owl	inositol phosphorylceramide metabolic process|inositol phosphorylceramide metabolism|inositolphosphoceramide metabolism											GO:0006674		biological_process											owl:Class	
GO:0051786	biolink:NamedThing	all-trans-retinol 13,14-reductase activity	Catalysis of the reaction: all-trans-13,14-dihydroretinol + A = all-trans-retinol + AH(2). Note that this reaction has only been observed to occur in the opposite direction.	tmpzr1t_l9r_go_relaxed.owl	RetSat activity|(13,14)-all-trans-retinol saturase activity|all-trans-13,14-dihydroretinol:acceptor 13,14-oxidoreductase activity|retinol saturase activity|all-trans-retinol:all-trans-13,14-dihydroretinol saturase activity				MetaCyc:1.3.99.23-RXN|Reactome:R-HSA-8956427|RHEA:19193|KEGG_REACTION:R07163|EC:1.3.99.23									molecular_function											owl:Class	
GO:0048279	biolink:NamedThing	vesicle fusion with endoplasmic reticulum	The joining of the lipid bilayer membrane around a vesicle to the lipid bilayer membrane around the endoplasmic reticulum.	tmpzr1t_l9r_go_relaxed.owl	vesicle fusion with ER													biological_process											owl:Class	
GO:1902323	biolink:NamedThing	negative regulation of methyl-branched fatty acid biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of methyl-branched fatty acid biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of methyl-branched fatty acid biosynthetic process|negative regulation of methyl-branched fatty acid synthesis|downregulation of methyl-branched fatty acid biosynthesis|downregulation of methyl-branched fatty acid synthesis|downregulation of methyl-branched fatty acid anabolism|inhibition of methyl-branched fatty acid biosynthetic process|down regulation of methyl-branched fatty acid biosynthesis|down regulation of methyl-branched fatty acid formation|down regulation of methyl-branched fatty acid anabolism|down regulation of methyl-branched fatty acid biosynthetic process|negative regulation of methyl-branched fatty acid anabolism|down-regulation of methyl-branched fatty acid anabolism|inhibition of methyl-branched fatty acid formation|negative regulation of methyl-branched fatty acid formation|down regulation of methyl-branched fatty acid synthesis|down-regulation of methyl-branched fatty acid synthesis|inhibition of methyl-branched fatty acid biosynthesis|downregulation of methyl-branched fatty acid formation|downregulation of methyl-branched fatty acid biosynthetic process|down-regulation of methyl-branched fatty acid biosynthesis|down-regulation of methyl-branched fatty acid formation|inhibition of methyl-branched fatty acid anabolism|inhibition of methyl-branched fatty acid synthesis|negative regulation of methyl-branched fatty acid biosynthesis							kmv	2013-07-24T20:15:23Z					biological_process											owl:Class	
GO:1903936	biolink:NamedThing	cellular response to sodium arsenite	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sodium arsenite stimulus.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-02-12T20:54:53Z					biological_process											owl:Class	
GO:1903935	biolink:NamedThing	response to sodium arsenite	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sodium arsenite stimulus.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-02-12T20:54:33Z					biological_process											owl:Class	
GO:0000387	biolink:NamedThing	spliceosomal snRNP assembly	The aggregation, arrangement and bonding together of one or more snRNA and multiple protein components to form a ribonucleoprotein complex that is involved in formation of the spliceosome.	tmpzr1t_l9r_go_relaxed.owl	spliceosomal snRNP biogenesis													biological_process											owl:Class	
GO:0015727	biolink:NamedThing	lactate transport	The directed movement of lactate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Lactate is 2-hydroxypropanoate, CH3-CHOH-COOH; L(+)-lactate is formed by anaerobic glycolysis in animal tissues, and DL-lactate is found in sour milk, molasses and certain fruit juices.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0034998	biolink:NamedThing	oligosaccharyltransferase I complex	An oligosaccharyltransferase (OST) complex that contains at least seven polypeptides and is the major OST complex in mammalian cells. Of the three forms of mammalian OST complex identified, the OSTI complex has the weakest affinity for ribosomes.	tmpzr1t_l9r_go_relaxed.owl	OSTCI													cellular_component											owl:Class	
GO:0061221	biolink:NamedThing	mesonephric mesenchyme morphogenesis	The process in which the anatomical structures of a mesonephric mesenchymal tissue are generated and organized. Mesonephric mesenchyme is the tissue made up of loosely connected mesenchymal cells in the mesonephros.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-08-19T01:17:38Z					biological_process											owl:Class	
GO:0007189	biolink:NamedThing	adenylate cyclase-activating G protein-coupled receptor signaling pathway	The series of molecular signals generated as a consequence of a G protein-coupled receptor binding to its physiological ligand, where the pathway proceeds through activation of adenylyl cyclase activity and a subsequent increase in the concentration of cyclic AMP (cAMP).	tmpzr1t_l9r_go_relaxed.owl	G protein signaling, adenylate cyclase activating pathway|G protein signalling, adenylyl cyclase activating pathway|G protein signalling, adenylate cyclase activating pathway|G-protein signalling, adenylate cyclase activating pathway|positive regulation of adenylate cyclase activity by G-protein signaling pathway|G-protein signalling, adenylyl cyclase activating pathway|G-protein signaling, adenylyl cyclase activating pathway|positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway|G protein signaling, adenylyl cyclase activating pathway|adenylate cyclase-activating GPCR signaling pathway|GPCR signaling pathway via activation of adenylate cyclase activity|GPCR signaling pathway via activation of adenylate cyclase|positive regulation of adenylate cyclase activity by G-protein signalling pathway|activation of adenylate cyclase activity by G-protein signaling pathway|activation of adenylate cyclase activity involved in G-protein signaling|G-protein signaling, adenylate cyclase activating pathway					This term can be used to annotate ligands, receptors and G-proteins that lead to activation of adenylate cyclase activity within a signaling pathway.						GO:0010579|GO:0010580		biological_process											owl:Class	
GO:0071995	biolink:NamedThing	phytochelatin import into vacuole	The directed movement of phytochelatins into the vacuole. Phytochelatins are a group of peptides that bind metals (Cd, Zn, Cu, Pb, Hg) in thiolate coordination complexes.	tmpzr1t_l9r_go_relaxed.owl	phytochelatin transport into vacuole|cadystin import into vacuole							mah	2010-10-25T02:01:59Z					biological_process											owl:Class	
GO:0030232	biolink:NamedThing	insulin control element activator complex	Transcription factor complex that binds to the insulin control element (ICE), a DNA sequence element found within the 5'-flanking region of the insulin gene, and activates ICE-mediated transcription.	tmpzr1t_l9r_go_relaxed.owl	ICE activator complex													cellular_component											owl:Class	
GO:0070003	biolink:NamedThing	threonine-type peptidase activity	Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a mechanism in which the hydroxyl group of a threonine residue at the active center acts as a nucleophile.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0035508	biolink:NamedThing	positive regulation of myosin-light-chain-phosphatase activity	Any process that activates or increases the frequency, rate or extent of myosin-light-chain-phosphatase activity.	tmpzr1t_l9r_go_relaxed.owl								bf	2010-04-30T10:55:05Z					biological_process											owl:Class	
GO:1901333	biolink:NamedThing	positive regulation of lateral root development	Any process that activates or increases the frequency, rate or extent of lateral root development.	tmpzr1t_l9r_go_relaxed.owl	activation of lateral root development|up regulation of lateral root development|upregulation of lateral root development|up-regulation of lateral root development							tb	2012-09-01T00:59:46Z					biological_process											owl:Class	
GO:0016099	biolink:NamedThing	monoterpenoid biosynthetic process	The chemical reactions and pathways resulting in the formation of monoterpenoid compounds, terpenoids having a C10 skeleton.	tmpzr1t_l9r_go_relaxed.owl	monoterpenoid anabolism|monoterpenoid formation|monoterpenoid synthesis|monoterpenoid biosynthesis				MetaCyc:PWY-3041									biological_process											owl:Class	
GO:0046945	biolink:NamedThing	N-terminal peptidyl-alanine N-carbamoylation	The carbamylation of the N-terminal alanine of proteins to form the derivative N-carbamoyl-L-alanine.	tmpzr1t_l9r_go_relaxed.owl	N-terminal peptidyl-alanine N-carbamylation				RESID:AA0343									biological_process											owl:Class	
GO:0046944	biolink:NamedThing	protein carbamoylation	The addition of a carbamoyl group to a protein amino acid. A carbamoyl group is the acyl group -CO-NH2.	tmpzr1t_l9r_go_relaxed.owl	protein amino acid carbamoylation													biological_process											owl:Class	
GO:2001247	biolink:NamedThing	positive regulation of phosphatidylcholine biosynthetic process	Any process that activates or increases the frequency, rate or extent of phosphatidylcholine biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of phosphatidylcholine anabolism|positive regulation of phosphatidylcholine synthesis|positive regulation of phosphatidylcholine formation|positive regulation of phosphatidylcholine biosynthesis							tb	2011-11-28T09:47:54Z					biological_process											owl:Class	
GO:0150173	biolink:NamedThing	positive regulation of phosphatidylcholine metabolic process	Any process that activates or increases the frequency, rate or extent of phosphatidylcholine metabolic process.	tmpzr1t_l9r_go_relaxed.owl								bc	2020-01-21T14:03:28Z					biological_process											owl:Class	
GO:0018050	biolink:NamedThing	C-terminal peptidyl-threonine amidation	The formation of a C-terminal peptidyl-threonine amide by hydrolysis and oxidation of an interior Thr-Gly peptide in a secreted protein.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0097									biological_process											owl:Class	
GO:0035346	biolink:NamedThing	positive regulation of hypoxanthine transport	Any process that activates or increases the frequency, rate or extent of the directed movement of hypoxanthine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of 6-hydroxypurine transport							bf	2010-03-04T10:42:48Z					biological_process											owl:Class	
GO:0008420	biolink:NamedThing	RNA polymerase II CTD heptapeptide repeat phosphatase activity	Catalysis of the reaction: phospho-(DNA-directed RNA polymerase II) + H2O = (DNA-directed RNA polymerase II) + phosphate.	tmpzr1t_l9r_go_relaxed.owl	CTD phosphatase activity|RNA polymerase II carboxy-terminal domain phosphatase activity													molecular_function											owl:Class	
GO:0052165	biolink:NamedThing	symbiont defense to host-produced phytoalexin	Any process in which a symbiont modulates the frequency, rate or extent of production of phytoalexins as part of the defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	modulation by organism of phytoalexin production in other organism involved in symbiotic interaction|evasion or tolerance of phytoalexins|phytoalexin detoxification|host phytoalexin detoxification|modulation by symbiont of host phytoalexin production|response to host phytoalexin production|response to phytoalexin production by other organism involved in symbiotic interaction|evasion or tolerance by symbiont of host-produced phytoalexins|evasion or tolerance of phytoalexins produced by host in response to organism	https://github.com/geneontology/go-ontology/issues/18798										GO:0052304|GO:0052378|GO:0052061|GO:0052549|GO:0052566		biological_process											owl:Class	
GO:0070133	biolink:NamedThing	negative regulation of mitochondrial translational initiation	Any process that stops, prevents, or reduces the frequency, rate or extent of the process preceding formation of the peptide bond between the first two amino acids of a protein in a mitochondrion.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of mitochondrial translation initiation													biological_process											owl:Class	
GO:0045993	biolink:NamedThing	negative regulation of translational initiation by iron	Any process involving iron that stops, prevents or reduces the rate of translational initiation.	tmpzr1t_l9r_go_relaxed.owl	downregulation of translational initiation by iron|inhibition of translational initiation by iron|down-regulation of translational initiation by iron|down regulation of translational initiation by iron													biological_process											owl:Class	
GO:0006447	biolink:NamedThing	regulation of translational initiation by iron	Any process that modulates the frequency, rate or extent of the translation of certain mRNAs involved in iron metabolism; regulated by the concentration of iron.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0047264	biolink:NamedThing	heteroglycan alpha-mannosyltransferase activity	Catalysis of the reaction: heteroglycan + GDP-mannose = alpha-D-mannosylheteroglycan + GDP.	tmpzr1t_l9r_go_relaxed.owl	GDP mannose alpha-mannosyltransferase activity|heteropolysaccharide alpha-mannosyltransferase activity|guanosine diphosphomannose-heteroglycan alpha-mannosyltransferase activity|GDP-mannose:heteroglycan 2-(or 3-)-alpha-D-mannosyltransferase activity				EC:2.4.1.48									molecular_function											owl:Class	
GO:2000567	biolink:NamedThing	regulation of memory T cell activation	Any process that modulates the frequency, rate or extent of memory T cell activation.	tmpzr1t_l9r_go_relaxed.owl								ebc	2011-04-03T09:10:06Z					biological_process											owl:Class	
GO:0002907	biolink:NamedThing	positive regulation of mature B cell apoptotic process	Any process that activates or increases the frequency, rate, or extent of mature B cell apoptotic process.	tmpzr1t_l9r_go_relaxed.owl	up regulation of mature B cell apoptosis|activation of mature B cell apoptosis|positive regulation of mature B cell apoptosis|up-regulation of mature B cell apoptosis|stimulation of mature B cell apoptosis|upregulation of mature B cell apoptosis													biological_process											owl:Class	
GO:0010142	biolink:NamedThing	farnesyl diphosphate biosynthetic process, mevalonate pathway	The pathway that converts acetate, in the form of acetyl-CoA, to farnesyl diphosphate (FPP) through a series of mevalonate intermediates. Farnesyl diphosphate is an important substrate for other essential pathways, such as biosynthesis of sterols.	tmpzr1t_l9r_go_relaxed.owl	farnesyl diphosphate formation, mevalonate pathway|farnesyl diphosphate synthesis, mevalonate pathway|Ac-MVA pathway|farnesyl diphosphate anabolism, mevalonate pathway|isoprenoid pathway|acetate-mevalonate pathway				MetaCyc:PWY-922									biological_process											owl:Class	
GO:0051760	biolink:NamedThing	meiotic sister chromatid cohesion, arms	The cell cycle process in which the sister chromatids of a replicated chromosome are joined along the length of the chromosome arms during meiosis.	tmpzr1t_l9r_go_relaxed.owl	meiotic sister chromatid cohesion along arms|sister chromatid cohesion along arms at meiosis I													biological_process											owl:Class	
GO:0042897	biolink:NamedThing	polymyxin transmembrane transporter activity	Enables the transfer of polymyxin, any of a group of related antibiotics produced by Bacillus polymyxa and active against most Gram-negative bacteria, from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	polymyxin transporter activity													molecular_function											owl:Class	
GO:0002281	biolink:NamedThing	macrophage activation involved in immune response	A change in morphology and behavior of a macrophage resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response.	tmpzr1t_l9r_go_relaxed.owl	macrophage activation during immune response|macrophage polarization involved in immune response													biological_process											owl:Class	
GO:0002275	biolink:NamedThing	myeloid cell activation involved in immune response	A change in the morphology or behavior of a myeloid cell resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response.	tmpzr1t_l9r_go_relaxed.owl	myeloid cell activation during immune response													biological_process											owl:Class	
GO:0102895	biolink:NamedThing	colneleate synthase activity	Catalysis of the reaction: 9(S)-HPODE <=> colneleate + H2O.	tmpzr1t_l9r_go_relaxed.owl					RHEA:28174|MetaCyc:RXN-8496|EC:4.2.1.121									molecular_function											owl:Class	
GO:0018112	biolink:NamedThing	proline racemase activity	Catalysis of the reaction: L-proline = D-proline.	tmpzr1t_l9r_go_relaxed.owl					EC:5.1.1.4|MetaCyc:PROLINE-RACEMASE-RXN|RHEA:10680|KEGG_REACTION:R01255									molecular_function											owl:Class	
GO:0120099	biolink:NamedThing	procentriole replication complex	A protein complex that acts as a chaperone or scaffold for centriolar proteins during the maturation of the procentriole. Some of its members may become integrated into the growing centriole. Examples are the CPAP(CENPJ)-STIL complex, CEP192-PLK4 complex or CEP152-PLK4 complex in vertebrates.	tmpzr1t_l9r_go_relaxed.owl								krc	2017-09-28T21:41:34Z					cellular_component											owl:Class	
GO:1990162	biolink:NamedThing	histone deacetylase activity (H3-K4 specific)	Catalysis of the reaction: histone H3 N6-acetyl-L-lysine (position 4) + H2O = histone H3 L-lysine (position 4) + acetate. This reaction represents the removal of an acetyl group from lysine at position 4 of the histone H3 protein.	tmpzr1t_l9r_go_relaxed.owl								pr	2013-08-06T08:48:44Z					molecular_function											owl:Class	
GO:0032604	biolink:NamedThing	granulocyte macrophage colony-stimulating factor production	The appearance of granulocyte macrophage colony-stimulating factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	tmpzr1t_l9r_go_relaxed.owl	granulocyte macrophage colony stimulating factor production|GM-CSF production|granulocyte macrophage colony-stimulating factor biosynthetic process											GO:0042253		biological_process											owl:Class	
GO:0071121	biolink:NamedThing	alpha9-beta1 integrin-VEGF-D complex	A protein complex that consists of an alpha9-beta1 integrin complex bound to vascular endothelial growth factor D.	tmpzr1t_l9r_go_relaxed.owl	ITGA9-ITGB1-FIGF complex							mah	2009-11-13T02:21:37Z					cellular_component											owl:Class	
GO:1902167	biolink:NamedThing	positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	Any process that activates or increases the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator.	tmpzr1t_l9r_go_relaxed.owl	upregulation of DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis|activation of DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis|up-regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator|upregulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator|up regulation of DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis|activation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator|up regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator|positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis|up-regulation of DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis							lb	2013-05-22T12:45:20Z					biological_process											owl:Class	
GO:1901760	biolink:NamedThing	beta-L-Ara4N-lipid A biosynthetic process	The chemical reactions and pathways resulting in the formation of beta-L-Ara4N-lipid A which occurs as a result of modification of the lipid A moiety of lipopolysaccharide by the addition of the sugar 4-amino-4-deoxy-L-arabinose (L-Ara4N). This strategy is adopted by pathogenic Gram-negative bacteria to evade cationic antimicrobial peptides produced by the innate immune system.	tmpzr1t_l9r_go_relaxed.owl	beta-L-Ara4N-lipid A anabolism|beta-L-Ara4N-lipid A synthesis|4-amino-4-deoxy-beta-L-arabinose-lipid A biosynthetic process|4-amino-4-deoxy-beta-L-arabinose-lipid A biosynthesis|beta-L-Ara4N-lipid A formation|beta-L-Ara4N-lipid A biosynthesis							pr	2013-01-14T12:53:01Z					biological_process											owl:Class	
GO:0102810	biolink:NamedThing	glutarate-semialdehyde dehydrogenase (NADP+) activity	Catalysis of the reaction: 5-oxopentanoate + NADP + H2O = glutarate + NADPH + 2 H+.	tmpzr1t_l9r_go_relaxed.owl					RHEA:57832|MetaCyc:RXN-8182									molecular_function											owl:Class	
GO:0140586	biolink:NamedThing	promoter-terminator loop anchoring activity	Bridging together a cis-regulatory element and a terminator DNA sequences on the chromatin, holding two loop anchors together, maintaining a chromatin loop.	tmpzr1t_l9r_go_relaxed.owl	terminator-promoter loop anchoring activity	https://github.com/geneontology/go-ontology/issues/20204				Note that GO does not separately defines enhancers, since this concept is very close to that of cis-regulatory elements. However the literature refers to 'promoter-enhancer loops' to describe loops that bring together cis-regulatory elements. Note also that while SO defines 'promoter' as the core promoter, here it is used to mean a cis-regulatory element.		pg	2021-02-04T14:51:44Z					molecular_function											owl:Class	
GO:0070967	biolink:NamedThing	coenzyme F420 binding	Binding to F420, the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-10-02T11:33:26Z					molecular_function											owl:Class	
GO:0016158	biolink:NamedThing	3-phytase activity	Catalysis of the reaction: myo-inositol hexakisphosphate + H2O = D-myo-inositol 1,2,4,5,6-pentakisphosphate + phosphate.	tmpzr1t_l9r_go_relaxed.owl	myo-inositol-hexakisphosphate 3-phosphohydrolase activity|myo-inositol-hexaphosphate 3-phosphohydrolase activity|phytate 1-phosphatase activity|phytate 3-phosphatase activity|phytase activity|1-phytase activity				MetaCyc:RXN0-1001|EC:3.1.3.8|RHEA:16989									molecular_function											owl:Class	
GO:0018167	biolink:NamedThing	protein-phycoerythrobilin linkage via phycoerythrobilin-bis-L-cysteine	The linkage of the chromophore phycoerythrobilin to phycoerythrin via phycoerythrobilin-bis-L-cysteine.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0259									biological_process											owl:Class	
GO:0072215	biolink:NamedThing	regulation of metanephros development	Any process that modulates the rate, frequency or extent of metanephros development. Metanephros development is the process whose specific outcome is the progression of the metanephros over time, from its formation to the mature structure. The metanephros is an endocrine and metabolic organ that filters the blood and excretes the end products of body metabolism in the form of urine.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0042117	biolink:NamedThing	monocyte activation	The change in morphology and behavior of a monocyte resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0002274	biolink:NamedThing	myeloid leukocyte activation	A change in the morphology or behavior of a myeloid leukocyte resulting from exposure to an activating factor such as a cellular or soluble ligand.	tmpzr1t_l9r_go_relaxed.owl	myeloid leucocyte activation													biological_process											owl:Class	
GO:0031982	biolink:NamedThing	vesicle	Any small, fluid-filled, spherical organelle enclosed by membrane.	tmpzr1t_l9r_go_relaxed.owl	membrane-enclosed vesicle|membrane-bounded vesicle				NIF_Subcellular:sao221389602|Wikipedia:Vesicle_(biology)							GO:0031988		cellular_component											owl:Class	
GO:0150146	biolink:NamedThing	cell junction disassembly	The disaggregation of a cell junction into its constituent components.	tmpzr1t_l9r_go_relaxed.owl								bc	2019-12-08T11:12:13Z					biological_process											owl:Class	
GO:1900749	biolink:NamedThing	(R)-carnitine transport	The directed movement of a (R)-carnitine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	C7H15NO3 transport|Vitamin BT transport|Carnicor transport|Carnitene transport|(-)-Carnitine transport|(3R)-3-hydroxy-4-(trimethylammonio)butanoate transport|Carnitine transport|Carnitor transport|Levocarnitine transport|(-)-L-Carnitine transport|L-Carnitine transport							jl	2012-05-29T02:01:17Z					biological_process											owl:Class	
GO:0015879	biolink:NamedThing	carnitine transport	The directed movement of carnitine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Carnitine is a compound that participates in the transfer of acyl groups across the inner mitochondrial membrane.	tmpzr1t_l9r_go_relaxed.owl	vitamin Bt transport													biological_process											owl:Class	
GO:0022614	biolink:NamedThing	membrane to membrane docking	The initial attachment of a membrane to a target membrane, mediated by proteins protruding from the two membranes. Docking requires only that the membranes come close enough for the proteins to interact and adhere.	tmpzr1t_l9r_go_relaxed.owl	membrane-membrane docking													biological_process											owl:Class	
GO:0036135	biolink:NamedThing	Schwann cell migration	The orderly movement of a Schwann cell from one site to another. A Schwann cell is a glial cell that ensheathes axons of neuron in the peripheral nervous system and is necessary for their maintainance and function.	tmpzr1t_l9r_go_relaxed.owl								bf	2012-03-06T10:44:39Z					biological_process											owl:Class	
GO:0045495	biolink:NamedThing	pole plasm	Differentiated cytoplasm associated with a pole (animal, vegetal, anterior, or posterior) of an oocyte, egg or early embryo.	tmpzr1t_l9r_go_relaxed.owl	polar plasm|germ plasm													cellular_component											owl:Class	
GO:0036165	biolink:NamedThing	invasive growth in response to heat	The growth of colonies in filamentous chains of cells as a result of an increase in temperature.	tmpzr1t_l9r_go_relaxed.owl	invasive growth in response to high temperature|invasive growth in response to elevated temperature|invasive growth in response to temperature stimulus							bf	2012-03-27T11:23:03Z					biological_process											owl:Class	
GO:0050035	biolink:NamedThing	L-sorbose oxidase activity	Catalysis of the reaction: L-sorbose + O(2) = 5-dehydro-D-fructose + H(2)O(2).	tmpzr1t_l9r_go_relaxed.owl	L-sorbose:oxygen 5-oxidoreductase activity				MetaCyc:L-SORBOSE-OXIDASE-RXN|RHEA:17853|EC:1.1.3.11|KEGG_REACTION:R01695									molecular_function											owl:Class	
GO:2001112	biolink:NamedThing	regulation of cellular response to hepatocyte growth factor stimulus	Any process that modulates the frequency, rate or extent of cellular response to hepatocyte growth factor stimulus.	tmpzr1t_l9r_go_relaxed.owl	regulation of cellular response to HGF stimulus							dph	2011-10-05T05:43:18Z					biological_process											owl:Class	
GO:0010800	biolink:NamedThing	positive regulation of peptidyl-threonine phosphorylation	Any process that increases the frequency, rate or extent of peptidyl-threonine phosphorylation. Peptidyl-threonine phosphorylation is the phosphorylation of peptidyl-threonine to form peptidyl-O-phospho-L-threonine.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1903222	biolink:NamedThing	quinolinic acid transmembrane transport	The process in which quinolinic acid is transported across a membrane.	tmpzr1t_l9r_go_relaxed.owl								di	2014-07-26T07:29:07Z					biological_process											owl:Class	
GO:0032469	biolink:NamedThing	endoplasmic reticulum calcium ion homeostasis	Any process involved in the maintenance of an internal steady state of calcium ions within the endoplasmic reticulum of a cell or between the endoplasmic reticulum and its surroundings.	tmpzr1t_l9r_go_relaxed.owl	regulation of ER calcium ion concentration|regulation of calcium ion concentration in endoplasmic reticulum|calcium ion homeostasis in ER|ER calcium ion homeostasis|calcium ion homeostasis in endoplasmic reticulum|regulation of calcium ion concentration in ER|regulation of endoplasmic reticulum calcium ion concentration|endoplasmic reticulum calcium ion concentration regulation|ER calcium ion concentration regulation													biological_process											owl:Class	
GO:0042284	biolink:NamedThing	sphingolipid delta-4 desaturase activity	Catalysis of the reaction: a dihydroceramide + 2 ferrocytochrome b5 + O2 + 2 H+ -> a sphingosine ceramide (aka (4E)-sphing-4-enine ceramide) + 2 ferricytochrome b5 + 2 H2O.	tmpzr1t_l9r_go_relaxed.owl	delta-4 sphingolipid desaturase activity	https://github.com/geneontology/go-ontology/issues/21105			EC:1.14.19.17|Reactome:R-HSA-428259|RHEA:46544									molecular_function											owl:Class	
GO:0042301	biolink:NamedThing	phosphate ion binding	Binding to a phosphate ion.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0043606	biolink:NamedThing	formamide metabolic process	The chemical reactions and pathways involving formamide, the simplest amide, HCONH2, derived from formic acid.	tmpzr1t_l9r_go_relaxed.owl	formamide metabolism													biological_process											owl:Class	
GO:0047325	biolink:NamedThing	inositol tetrakisphosphate 1-kinase activity	Catalysis of the reaction: 1D-myo-inositol 3,4,5,6-tetrakisphosphate + ATP = 1D-myo-inositol 1,3,4,5,6-pentakisphosphate + ADP.	tmpzr1t_l9r_go_relaxed.owl	1D-myo-inositol-trisphosphate 6-kinase activity|inositol-trisphosphate 6-kinase activity|inositol 3,4,5,6-tetrakisphosphate 1-kinase activity|1D-myo-inositol-trisphosphate 5-kinase activity|inositol-tetrakisphosphate 1-kinase activity|inositol-trisphosphate 5-kinase activity|1D-myo-inositol-tetrakisphosphate 1-kinase activity|ATP:1D-myo-inositol-3,4,5,6-tetrakisphosphate 1-phosphotransferase activity				Reactome:R-HSA-994137|RHEA:12452|MetaCyc:2.7.1.134-RXN|EC:2.7.1.134|Reactome:R-HSA-1855162									molecular_function											owl:Class	
GO:0061307	biolink:NamedThing	cardiac neural crest cell differentiation involved in heart development	The process in which a relatively unspecialized cell acquires specialized features of a cardiac neural crest cell that will migrate to the heart and contribute to its development. Cardiac neural crest cells are specialized cells that migrate toward the heart from the third, fourth and sixth pharyngeal arches.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-09-23T08:50:56Z					biological_process											owl:Class	
GO:0015298	biolink:NamedThing	solute:cation antiporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: solute(out) + cation(in) = solute(in) + cation(out).	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0030776	biolink:NamedThing	(RS)-1-benzyl-1,2,3,4-tetrahydroisoquinoline N-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + (RS)-1-benzyl-1,2,3,4-tetrahydroisoquinoline = S-adenosyl-L-homocysteine + N-methyl-(RS)-1-benzyl-1,2,3,4-tetrahydroisoquinoline.	tmpzr1t_l9r_go_relaxed.owl	(RS)-tetrahydrobenzylisoquinoline N-methyltransferase activity|S-adenosyl-L-methionine:(RS)-1-benzyl-1,2,3,4-tetrahydroisoquinoline N-methyltransferase activity|norreticuline N-methyltransferase activity				MetaCyc:2.1.1.115-RXN|RHEA:13005|EC:2.1.1.115									molecular_function											owl:Class	
GO:0030787	biolink:NamedThing	inositol 4-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine(1+) + myo-inositol = 1D-4-O-methyl-myo-inositol + S-adenosyl-L-homocysteine + H(+).	tmpzr1t_l9r_go_relaxed.owl	S-adenosyl-L-methionine:myo-inositol 4-O-methyltransferase activity|S-adenosyl-L-methionine:1D-myo-inositol 4-methyltransferase activity|myo-inositol 4-O-methyltransferase activity|myo-inositol 6-O-methyltransferase activity				KEGG_REACTION:R01190|RHEA:23248|MetaCyc:2.1.1.129-RXN|EC:2.1.1.129									molecular_function											owl:Class	
GO:0000776	biolink:NamedThing	kinetochore	A multisubunit complex that is located at the centromeric region of DNA and provides an attachment point for the spindle microtubules.	tmpzr1t_l9r_go_relaxed.owl	condensed nuclear chromosome kinetochore|condensed chromosome kinetochore	https://github.com/geneontology/go-ontology/issues/21126			Wikipedia:Kinetochore	Note that the kinetochore overlaps the centromeric DNA, but centromeric DNA is not part of the kinetochore.						GO:0000777|GO:0005699|GO:0000778		cellular_component											owl:Class	
GO:0003070	biolink:NamedThing	regulation of systemic arterial blood pressure by neurotransmitter	The regulation of blood pressure mediated by a neurotransmitter. A neurotransmitter is any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0150144	biolink:NamedThing	negative regulation of CD80 production	Any process that stops, prevents or reduces the frequency, rate or extent of CD80 biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of CD80 biosynthetic process							bc	2019-12-08T10:26:42Z					biological_process											owl:Class	
GO:0003087	biolink:NamedThing	positive regulation of the force of heart contraction by neuronal epinephrine	The process in which the release of epinephrine from nerve endings modulates the force of heart muscle contraction.	tmpzr1t_l9r_go_relaxed.owl	increased force of heart contraction by neuronal adrenaline|increased force of heart contraction by epinephrine released from the nerve endings|positive regulation of heart contraction by adrenaline|increased force of heart contraction by neuronal epinephrine|positive regulation of heart contraction by neuronal epinephrine													biological_process											owl:Class	
GO:1904315	biolink:NamedThing	transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential	Any transmitter-gated ion channel activity that is involved in regulation of postsynaptic membrane potential.	tmpzr1t_l9r_go_relaxed.owl	ionotropic neurotransmitter receptor activity involved in regulation of post-synaptic membrane potential|ionotropic neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential							dos	2015-06-10T18:02:07Z					molecular_function											owl:Class	
GO:0009145	biolink:NamedThing	purine nucleoside triphosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of purine nucleoside triphosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with triphosphate on the sugar.	tmpzr1t_l9r_go_relaxed.owl	purine nucleoside triphosphate biosynthesis|purine nucleoside triphosphate formation|purine nucleoside triphosphate synthesis|purine nucleoside triphosphate anabolism													biological_process											owl:Class	
GO:0097515	biolink:NamedThing	asexual spore wall	A specialized envelope lying outside the cell membrane of a spore derived from an asexual process. Examples of this process are found in bacterial and fungal species.	tmpzr1t_l9r_go_relaxed.owl								pr	2013-10-16T15:11:21Z					cellular_component											owl:Class	
GO:0061119	biolink:NamedThing	regulation of positive chemotaxis to cAMP by chlorinated alkylphenone	Any process that modulates the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of a chlorinated alkylphenone. An alkylphenone is an aromatic polyketide with methyl and chlorine substitutions.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-05-17T07:53:58Z					biological_process											owl:Class	
GO:0002091	biolink:NamedThing	negative regulation of receptor internalization	Any process that stops, prevents, or reduces the frequency, rate or extent of receptor internalization.	tmpzr1t_l9r_go_relaxed.owl	inhibition of receptor internalization|down regulation of receptor internalization|downregulation of receptor internalization|down-regulation of receptor internalization													biological_process											owl:Class	
GO:0034574	biolink:NamedThing	didemethylisoproturon dehydrogenase activity	Catalysis of the reaction: didemethylisoproturon + H2O = 4'-(2-hydroxyisopropyl)phenylurea + 2 H+ + 2 e-.	tmpzr1t_l9r_go_relaxed.owl					EC:1.17.99.-|UM-BBD_reactionID:r0899									molecular_function											owl:Class	
GO:0036310	biolink:NamedThing	ATP-dependent DNA/DNA annealing activity	An ATP-dependent activity that facilitates the formation of a complementary double-stranded DNA molecule.	tmpzr1t_l9r_go_relaxed.owl	ATP-dependent DNA annealing activity|DNA rewinding activity|annealing helicase activity|nucleoside-triphosphatase activity involved in DNA annealing	https://github.com/geneontology/go-ontology/issues/12465|https://github.com/geneontology/go-ontology/issues/9815|https://github.com/geneontology/go-ontology/issues/19669			Reactome:R-HSA-5686642			bf	2012-08-14T15:24:29Z					molecular_function											owl:Class	
GO:0034158	biolink:NamedThing	toll-like receptor 8 signaling pathway	Any series of molecular signals generated as a consequence of binding to toll-like receptor 8.	tmpzr1t_l9r_go_relaxed.owl	toll-like receptor 8 signalling pathway|TLR8 signaling pathway													biological_process											owl:Class	
GO:0102448	biolink:NamedThing	rhamnetin 4'-O-methyltransferase activity	Catalysis of the reaction: rhamnetin + S-adenosyl-L-methionine  <=> ombuin + S-adenosyl-L-homocysteine  + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-13934									molecular_function											owl:Class	
GO:0010379	biolink:NamedThing	phaseic acid biosynthetic process	The chemical reactions and pathways resulting in the formation of phaseic acid (PA), a catabolite of the plant hormone abscisic acid (ABA).	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:PWY-5271									biological_process											owl:Class	
GO:0021676	biolink:NamedThing	rhombomere 8 structural organization	The process that contributes to creating the structural organization of rhombomere 8. This process pertains to the physical shaping of a rudimentary structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.	tmpzr1t_l9r_go_relaxed.owl	rhombomere 8 structural organisation													biological_process											owl:Class	
GO:1990638	biolink:NamedThing	response to granulocyte colony-stimulating factor	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a granulocyte colony-stimulating factor stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to G-CSF							sl	2015-02-11T00:02:33Z					biological_process											owl:Class	
GO:0008993	biolink:NamedThing	rhamnulokinase activity	Catalysis of the reaction: ATP + L-rhamnulose = ADP + L-rhamnulose 1-phosphate.	tmpzr1t_l9r_go_relaxed.owl	L-rhamnulokinase activity|ATP:L-rhamnulose 1-phosphotransferase activity|rhamnulose kinase activity|L-rhamnulose kinase activity|rhamnulokinase (phosphorylating)|RhuK				MetaCyc:RHAMNULOKIN-RXN|EC:2.7.1.5|RHEA:20117									molecular_function											owl:Class	
GO:0071947	biolink:NamedThing	protein deubiquitination involved in ubiquitin-dependent protein catabolic process	The removal of one or more ubiquitin groups from a protein as part of a process of ubiquitin-dependent protein catabolism.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-10-06T02:06:10Z					biological_process											owl:Class	
GO:0042617	biolink:NamedThing	paclitaxel biosynthetic process	The chemical reactions and pathways resulting in the formation of paclitaxel, a tetracyclic diterpenoid isolated originally from the bark of the Pacific yew tree, Taxus brevifolia.	tmpzr1t_l9r_go_relaxed.owl	paclitaxel formation|taxol biosynthesis|paclitaxel biosynthesis|taxol biosynthetic process|paclitaxel synthesis|paclitaxel anabolism													biological_process											owl:Class	
GO:0002633	biolink:NamedThing	positive regulation of granuloma formation	Any process that activates or increases the frequency, rate, or extent of granuloma formation.	tmpzr1t_l9r_go_relaxed.owl	stimulation of granuloma formation|up regulation of granuloma formation|up-regulation of granuloma formation|upregulation of granuloma formation|activation of granuloma formation													biological_process											owl:Class	
GO:0014884	biolink:NamedThing	detection of muscle inactivity involved in regulation of muscle adaptation	The series of events in which a muscle inactivity stimulus is received by a cell and converted into a molecular signal. This occurs as part of the regulation of muscle adaptation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0060869	biolink:NamedThing	transmembrane receptor protein serine/threonine kinase signaling pathway involved in floral organ abscission	A series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell where the receptor possesses serine/threonine kinase activity, which contributes to the process of floral organ abscission.	tmpzr1t_l9r_go_relaxed.owl	transmembrane receptor protein serine/threonine kinase signalling pathway involved in floral organ abscission							dph	2009-08-12T07:02:07Z					biological_process											owl:Class	
GO:1905649	biolink:NamedThing	negative regulation of shell calcification	Any process that stops, prevents or reduces the frequency, rate or extent of shell calcification.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of shell calcification|downregulation of shell calcification|down regulation of shell calcification|inhibition of shell calcification							pga	2016-11-08T16:24:43Z					biological_process											owl:Class	
GO:0002795	biolink:NamedThing	negative regulation of antimicrobial peptide secretion	Any process that stops, prevents, or reduces the frequency, rate, or extent of antimicrobial peptide secretion.	tmpzr1t_l9r_go_relaxed.owl	down regulation of antimicrobial peptide secretion|inhibition of antimicrobial peptide secretion|down-regulation of antimicrobial peptide secretion|downregulation of antimicrobial peptide secretion													biological_process											owl:Class	
GO:0070065	biolink:NamedThing	cellubrevin-VAMP4-syntaxin-16 complex	A SNARE complex that contains cellubrevin (VAMP3), VAMP4, and syntaxin 16 (or orthologs thereof).	tmpzr1t_l9r_go_relaxed.owl	Vamp3-Vamp4-Stx16 complex|SNARE complex (Vamp3, Vamp4, Stx16)													cellular_component											owl:Class	
GO:1904250	biolink:NamedThing	positive regulation of age-related resistance	Any process that activates or increases the extent of age-related resistance.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of ARR|upregulation of ARR|upregulation of senescence-induced resistance|upregulation of flowering-induced resistance|upregulation of adult seedling resistance|positive regulation of senescence-induced resistance|up regulation of adult seedling resistance|up-regulation of adult seedling resistance|activation of flowering-induced resistance|up regulation of mature seedling resistance|up regulation of ARR|positive regulation of adult seedling resistance|positive regulation of flowering-induced resistance|activation of adult seedling resistance|up regulation of age-related resistance|positive regulation of ARR|up regulation of flowering-induced resistance|positive regulation of mature seedling resistance|up regulation of senescence-induced resistance|upregulation of mature seedling resistance|activation of age-related resistance|activation of ARR|activation of senescence-induced resistance|up-regulation of age-related resistance|upregulation of age-related resistance|up-regulation of flowering-induced resistance|up-regulation of senescence-induced resistance|activation of mature seedling resistance|up-regulation of mature seedling resistance							tb	2015-05-19T20:20:11Z					biological_process											owl:Class	
GO:1904248	biolink:NamedThing	regulation of age-related resistance	Any process that modulates the extent of age-related resistance.	tmpzr1t_l9r_go_relaxed.owl	regulation of ARR|regulation of developmental resistance|regulation of mature seedling resistance|regulation of ontogenic resistance|regulation of adult seedling resistance|regulation of senescence-induced resistance|regulation of flowering-induced resistance							tb	2015-05-19T20:19:58Z					biological_process											owl:Class	
GO:0050037	biolink:NamedThing	L-xylose 1-dehydrogenase activity	Catalysis of the reaction: aldehydo-L-xylose + NADP(+) = L-xylono-1,4-lactone + H(+) + NADPH.	tmpzr1t_l9r_go_relaxed.owl	L-xylose:NADP+ 1-oxidoreductase activity|NADPH-xylose reductase activity|L-xylose dehydrogenase activity				MetaCyc:L-XYLOSE-1-DEHYDROGENASE-RXN|EC:1.1.1.113|RHEA:15789|KEGG_REACTION:R03586									molecular_function											owl:Class	
GO:1900206	biolink:NamedThing	regulation of pronephric nephron tubule development	Any process that modulates the frequency, rate or extent of pronephric nephron tubule development.	tmpzr1t_l9r_go_relaxed.owl								bf	2012-03-22T09:23:13Z					biological_process											owl:Class	
GO:0000127	biolink:NamedThing	transcription factor TFIIIC complex	A heterotrimeric transcription factor complex that is involved in regulating transcription from RNA polymerase III (Pol III) promoters. TFIIIC contains three conserved subunits that associate with the proximal Pol III promoter element, and additional subunits that associate with sequence elements downstream of the promoter and are more diverged among species. It also functions as a boundary element to partition genome content into distinct domains outside Pol III promoter regions.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0007455	biolink:NamedThing	eye-antennal disc morphogenesis	The process in which the anatomical structures derived from the eye-antennal disc are generated and organized. This includes the transformation of an eye-antennal imaginal disc from a monolayered epithelium in the larvae of holometabolous insects into recognizable adult structures including the eye, antenna, head capsule and maxillary palps.	tmpzr1t_l9r_go_relaxed.owl	eye-antennal disc metamorphosis													biological_process											owl:Class	
GO:0018109	biolink:NamedThing	peptidyl-arginine phosphorylation	The phosphorylation of peptidyl-arginine to form omega-N-phospho-L-arginine.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0222									biological_process											owl:Class	
GO:0030576	biolink:NamedThing	Cajal body organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of Cajal bodies, nuclear bodies that appear ultrastructurally as a tangle of coiled, electron-dense threads roughly 0.5 micrometers in diameter and are enriched in ribonucleoproteins, and certain general RNA polymerase II transcription factors.	tmpzr1t_l9r_go_relaxed.owl	Cajal body organisation|Cajal body organization and biogenesis					See also the cellular component term 'Cajal body ; GO:0015030'.								biological_process											owl:Class	
GO:0047608	biolink:NamedThing	acetylindoxyl oxidase activity	Catalysis of the reaction: N-acetylindoxyl + O2 = N-acetylisatin + unknown.	tmpzr1t_l9r_go_relaxed.owl	N-acetylindoxyl:oxygen oxidoreductase activity				EC:1.7.3.2|MetaCyc:ACETYLINDOXYL-OXIDASE-RXN|RHEA:16941									molecular_function											owl:Class	
GO:0032177	biolink:NamedThing	cellular bud neck split septin rings	Two separate septin rings that are formed from the septin collar at the time of cytokinesis in cells that divide by budding. These two rings are thought to delineate a special compartment in which factors involved in cytokinesis are concentrated.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0032176	biolink:NamedThing	split septin rings	A pair of rings that flank the site of cell division, formed by splitting of the septin ring (or collar) prior to cytokinesis; this double ring structure is thought to trap proteins needed for cytokinesis or the formation of the new membrane or cell wall between the two septin rings. Split septin rings are known to occur in budding yeast cells and probably occur in other cell types as well.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:1903404	biolink:NamedThing	positive regulation of renal phosphate excretion	Any process that activates or increases the frequency, rate or extent of renal phosphate excretion.	tmpzr1t_l9r_go_relaxed.owl	upregulation of renal phosphate excretion|activation of renal phosphate excretion|up regulation of renal phosphate excretion|up-regulation of renal phosphate ion excretion|activation of renal phosphate ion excretion|positive regulation of renal phosphate ion excretion|upregulation of renal phosphate ion excretion|up-regulation of renal phosphate excretion|up regulation of renal phosphate ion excretion							pm	2014-09-01T13:47:18Z					biological_process											owl:Class	
GO:1903402	biolink:NamedThing	regulation of renal phosphate excretion	Any process that modulates the frequency, rate or extent of renal phosphate excretion.	tmpzr1t_l9r_go_relaxed.owl	regulation of renal phosphate ion excretion							pm	2014-09-01T13:47:01Z					biological_process											owl:Class	
GO:0005991	biolink:NamedThing	trehalose metabolic process	The chemical reactions and pathways involving trehalose, a disaccharide isomeric with sucrose and obtained from certain lichens and fungi.	tmpzr1t_l9r_go_relaxed.owl	mycose metabolic process|mykose metabolic process|mycose metabolism|trehalose metabolism|mykose metabolism													biological_process											owl:Class	
GO:0002453	biolink:NamedThing	peripheral B cell anergy	Any process contributing to anergy, a state of functional inactivation that occurs as part of tolerance induction, in peripheral B cells.	tmpzr1t_l9r_go_relaxed.owl	peripheral B-cell anergy|peripheral B lymphocyte anergy|peripheral B-lymphocyte anergy													biological_process											owl:Class	
GO:1900004	biolink:NamedThing	negative regulation of serine-type endopeptidase activity	Any process that stops, prevents or reduces the frequency, rate or extent of serine-type endopeptidase activity.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of blood coagulation factor activity|down regulation of serine-type endopeptidase activity|down regulation of blood coagulation factor activity							kmv	2012-01-09T10:03:20Z					biological_process											owl:Class	
GO:0060227	biolink:NamedThing	Notch signaling pathway involved in camera-type eye photoreceptor fate commitment	The series of molecular signals initiated by binding of an extracellular ligand to a Notch receptor on the surface of the target cell that contributes to the commitment of a precursor cell to a eye photoreceptor fate.	tmpzr1t_l9r_go_relaxed.owl	Notch signalling pathway involved in camera-type eye photoreceptor fate commitment													biological_process											owl:Class	
GO:0070017	biolink:NamedThing	alphav-beta3 integrin-thrombospondin complex	A protein complex that consists of an alphav-beta3 integrin complex bound to thrombospondin.	tmpzr1t_l9r_go_relaxed.owl	ITGAV-ITGB3-THBS1 complex													cellular_component											owl:Class	
GO:1903426	biolink:NamedThing	regulation of reactive oxygen species biosynthetic process	Any process that modulates the frequency, rate or extent of reactive oxygen species biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of ROS formation|regulation of reactive oxygen species biosynthesis|regulation of ROS generation|regulation of reactive oxygen species generation|regulation of reactive oxygen species formation|regulation of reactive oxygen species synthesis|regulation of reactive oxygen species anabolism							bf	2014-09-11T10:01:47Z					biological_process											owl:Class	
GO:0042404	biolink:NamedThing	thyroid hormone catabolic process	The chemical reactions and pathways resulting in the breakdown of any of the compounds secreted by the thyroid gland, largely thyroxine and triiodothyronine.	tmpzr1t_l9r_go_relaxed.owl	thyroid hormone degradation|thyroid hormone breakdown|thyroid hormone catabolism													biological_process											owl:Class	
GO:0018274	biolink:NamedThing	peptide cross-linking via L-lysinoalanine	The modification of peptidyl-lysine and peptidyl-serine to form a (2Xi,9S)-L-lysinoalanine cross-link.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0123									biological_process											owl:Class	
GO:0004711	biolink:NamedThing	ribosomal protein S6 kinase activity	Catalysis of the reaction: ribosomal protein S6 + ATP = ribosomal protein S6 phosphate + ATP.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0042195	biolink:NamedThing	aerobic gallate catabolic process	The chemical reactions and pathways resulting in the breakdown of gallate, the anion of gallic acid, in the presence of oxygen.	tmpzr1t_l9r_go_relaxed.owl	aerobic gallate breakdown|aerobic gallic acid catabolic process|aerobic gallic acid catabolism|aerobic gallate catabolism|aerobic gallate degradation													biological_process											owl:Class	
GO:0019396	biolink:NamedThing	gallate catabolic process	The chemical reactions and pathways resulting in the breakdown of gallate, the anion of gallic acid (3,4,5-trihydroxybenzoic acid).	tmpzr1t_l9r_go_relaxed.owl	gallic acid metabolic process|gallic acid catabolism|gallic acid metabolism|gallate metabolism|gallate catabolism|gallate metabolic process|gallic acid catabolic process|gallate breakdown|gallate degradation	https://github.com/geneontology/go-ontology/issues/20974			UM-BBD_pathwayID:gal							GO:0018918		biological_process											owl:Class	
GO:0052688	biolink:NamedThing	(3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (AMP-forming) activity	Catalysis of the reaction: (3R)-3-isopropenyl-6-oxoheptanoate + CoA-SH + ATP = H2O + AMP + diphosphate + (3R)-3-isopropenyl-6-oxoheptanoyl-CoA.	tmpzr1t_l9r_go_relaxed.owl	3-isopropenyl-6-oxoheptanoyl-CoA synthetase activity				KEGG_REACTION:R06515									molecular_function											owl:Class	
GO:0070833	biolink:NamedThing	phosphatidylcholine biosynthesis from phosphoryl-ethanolamine via CDP-N-methylethanolamine	The phosphatidylcholine biosynthetic process that begins with an initial N-methylation with phospho-base phosphoethanolamine, followed by two downstream N-methylations on phosphatidyl-bases, phosphatidyl-N-methylethanolamine and phosphatidyl-N-dimethylethanolamine. The process ends with the conversion of a phosphatidyl-N-dimethylethanolamine to a phosphatidylcholine.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:PWY4FS-3			mah	2009-07-29T03:51:39Z					biological_process											owl:Class	
GO:0007379	biolink:NamedThing	segment specification	The process in which segments assume individual identities; exemplified in insects by the actions of the products of the homeotic genes.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0042243	biolink:NamedThing	asexual spore wall assembly	The aggregation, arrangement and bonding together of a set of components to form an asexual spore wall, the specialized envelope lying outside the cell membrane of a spore derived from an asexual process. Examples of this process are found in Bacterial and Fungal species.	tmpzr1t_l9r_go_relaxed.owl	asexual spore wall formation													biological_process											owl:Class	
GO:0042244	biolink:NamedThing	spore wall assembly	The aggregation, arrangement and bonding together of a set of components to form a spore wall; a spore wall is the specialized envelope lying outside the cell membrane of a spore.	tmpzr1t_l9r_go_relaxed.owl	spore wall formation|spore coat biosynthetic process|spore coat biosynthesis													biological_process											owl:Class	
GO:0061284	biolink:NamedThing	specification of mesonephric proximal tubule identity	The process in which the proximal tubule of the mesonephric nephron acquires its identity.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-09-02T01:44:24Z					biological_process											owl:Class	
GO:0002580	biolink:NamedThing	regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II	Any process that modulates the frequency, rate, or extent of antigen processing and presentation of antigen (peptide or polysaccharide) via MHC class II.	tmpzr1t_l9r_go_relaxed.owl	regulation of peptide or polysaccharide antigen processing and presentation via MHC class II													biological_process											owl:Class	
GO:1902035	biolink:NamedThing	positive regulation of hematopoietic stem cell proliferation	Any process that activates or increases the frequency, rate or extent of hematopoietic stem cell proliferation.	tmpzr1t_l9r_go_relaxed.owl	up regulation of hematopoietic stem cell proliferation|upregulation of hemopoietic stem cell proliferation|activation of hematopoietic stem cell proliferation|up-regulation of hematopoietic stem cell proliferation|positive regulation of hemopoietic stem cell proliferation|upregulation of hematopoietic stem cell proliferation|up regulation of hemopoietic stem cell proliferation|up-regulation of hemopoietic stem cell proliferation|activation of hemopoietic stem cell proliferation							ss	2013-04-02T05:13:31Z					biological_process											owl:Class	
GO:1902875	biolink:NamedThing	regulation of embryonic pattern specification	Any process that modulates the frequency, rate or extent of embryonic pattern specification.	tmpzr1t_l9r_go_relaxed.owl	regulation of embryonic pattern formation|regulation of ventral/lateral system|regulation of embryonic pattern biosynthesis							mr	2014-04-03T15:25:15Z					biological_process											owl:Class	
GO:0046603	biolink:NamedThing	negative regulation of mitotic centrosome separation	Any process that stops, prevents, or reduces the frequency, rate or extent of centrosome separation.	tmpzr1t_l9r_go_relaxed.owl	inhibition of mitotic centrosome separation|down-regulation of mitotic centrosome separation|down regulation of mitotic centrosome separation|downregulation of mitotic centrosome separation													biological_process											owl:Class	
GO:0002156	biolink:NamedThing	negative regulation of thyroid hormone mediated signaling pathway	Any process that stops, prevents, or reduces the frequency, rate or extent of thyroid hormone mediated signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of thyroid hormone mediated signalling pathway							hjd	2009-11-19T12:41:48Z					biological_process											owl:Class	
GO:0000766	biolink:NamedThing	negative adaptation of signaling pathway by response to pheromone involved in pheromone-induced unidirectional conjugation	In organisms that undergo pheromone-induced unidirectional conjugation, the process involved in desensitization following exposure to pheromone stimulus that acts to down-regulate further stimulation or block initial conjugation responses.	tmpzr1t_l9r_go_relaxed.owl	adaptation to pheromone during pheromone-induced unidirectional conjugation|negative adaptation of signalling pathway by response to pheromone involved in pheromone-induced unidirectional conjugation|desensitization to pheromone during pheromone-induced unidirectional conjugation													biological_process											owl:Class	
GO:0032756	biolink:NamedThing	positive regulation of interleukin-7 production	Any process that activates or increases the frequency, rate, or extent of interleukin-7 production.	tmpzr1t_l9r_go_relaxed.owl	activation of interleukin-7 production|up-regulation of interleukin-7 production|upregulation of interleukin-7 production|positive regulation of IL-7 production|up regulation of interleukin-7 production|stimulation of interleukin-7 production|positive regulation of interleukin-7 secretion|positive regulation of interleukin-7 biosynthetic process											GO:0150114|GO:0045413		biological_process											owl:Class	
GO:0044828	biolink:NamedThing	negative regulation by host of viral genome replication	A process in which a host organism stops, prevents or reduces the frequency, rate or extent of viral genome replication.	tmpzr1t_l9r_go_relaxed.owl								jl	2014-02-06T11:34:23Z					biological_process											owl:Class	
GO:0061507	biolink:NamedThing	2',3'-cyclic GMP-AMP binding	Binding to 2',3' cyclic GMP-AMP (cGAMP) nucleotide, a cyclic purine dinucleotide that consists of AMP and GMP units cyclized via 2',5' and 3',5' linkages.	tmpzr1t_l9r_go_relaxed.owl	c[G(2',5')pA(3',5')p] binding|2',3'-cyclic GAMP binding|2',5-3',5'-cyclic GMP-AMP binding|2',3'-cGAMP binding|2',3' cyclic GAMP binding|cyclic-GMP-AMP binding|2',3' cGAMP binding	https://github.com/geneontology/go-ontology/issues/21980						dph	2013-01-24T15:38:27Z			GO:0098546		molecular_function											owl:Class	
GO:1905875	biolink:NamedThing	negative regulation of postsynaptic density organization	Any process that stops, prevents or reduces the frequency, rate or extent of postsynaptic density organization.	tmpzr1t_l9r_go_relaxed.owl	downregulation of postsynaptic density organization|downregulation of postsynaptic density organisation|down-regulation of postsynaptic density organization|negative regulation of postsynaptic density organisation|inhibition of post synaptic density organization|inhibition of PSD organization|down regulation of post synaptic density organization|down-regulation of post synaptic density organization|down-regulation of post-synaptic density organization|inhibition of postsynaptic density organization|downregulation of post-synaptic density organization|down regulation of postsynaptic density organisation|downregulation of post synaptic density organization|inhibition of postsynaptic density organisation|down regulation of post-synaptic density organization|negative regulation of post-synaptic density organization|downregulation of PSD organization|inhibition of post-synaptic density organization|negative regulation of PSD organization|down regulation of postsynaptic density organization|down-regulation of postsynaptic density organisation|down-regulation of PSD organization|negative regulation of post synaptic density organization|down regulation of PSD organization							sl	2017-01-27T19:53:41Z					biological_process											owl:Class	
GO:0042841	biolink:NamedThing	D-glucuronate biosynthetic process	The chemical reactions and pathways resulting in the formation of D-glucuronate, the D-enantiomer of glucuronate.	tmpzr1t_l9r_go_relaxed.owl	D-glucuronate formation|D-glucuronate anabolism|D-glucuronate synthesis|D-glucuronate biosynthesis													biological_process											owl:Class	
GO:0046399	biolink:NamedThing	glucuronate biosynthetic process	The chemical reactions and pathways resulting in the formation of glucuronate, the anion of glucuronic acid.	tmpzr1t_l9r_go_relaxed.owl	glucuronate anabolism|glucuronate formation|glucuronate biosynthesis|glucuronate synthesis													biological_process											owl:Class	
GO:0110068	biolink:NamedThing	glucosylglycerate phosphorylase activity	Catalysis of the reaction: glucosylglycerate + phosphate = glucose-1-phosphate + D-glycerate.	tmpzr1t_l9r_go_relaxed.owl								kmv	2017-11-21T21:50:10Z					molecular_function											owl:Class	
GO:0036518	biolink:NamedThing	chemorepulsion of dopaminergic neuron axon	The process in which a dopaminergic neuron growth cone is directed to a specific target site in response to a repulsive chemical cue.	tmpzr1t_l9r_go_relaxed.owl	chemorepulsion of DA axon|chemorepulsion of dopaminergic axon							bf	2015-12-17T11:29:09Z					biological_process											owl:Class	
GO:0090635	biolink:NamedThing	extracellular core region of desmosome	The desmosomal part containing the desmosomal cadherins, desmogleins and desmocollins, that establish contact and adhere to neighboring cells in a Ca2+-dependent manner.	tmpzr1t_l9r_go_relaxed.owl	desmoglea							tb	2015-04-20T16:10:51Z					cellular_component											owl:Class	
GO:1900192	biolink:NamedThing	positive regulation of single-species biofilm formation	Any process that activates or increases the frequency, rate or extent of single-species biofilm formation.	tmpzr1t_l9r_go_relaxed.owl	upregulation of single-species biofilm formation|activation of single-species biofilm formation|up regulation of single-species biofilm formation|up-regulation of single-species biofilm formation							di	2012-03-19T12:42:21Z					biological_process											owl:Class	
GO:0007187	biolink:NamedThing	G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger	The series of molecular signals generated as a consequence of a G protein-coupled receptor binding to its physiological ligand, where the pathway proceeds with activation or inhibition of a nucleotide cyclase activity and a subsequent change in the concentration of a cyclic nucleotide.	tmpzr1t_l9r_go_relaxed.owl	GPCR signaling pathway via cyclic nucleotide second messenger|G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger|G protein signalling, coupled to cyclic nucleotide second messenger|G protein signaling, coupled to cyclic nucleotide second messenger|G-protein signalling, coupled to cyclic nucleotide second messenger|G-protein signaling, coupled to cyclic nucleotide second messenger													biological_process											owl:Class	
GO:0052582	biolink:NamedThing	(+)-menthofuran synthase activity	Catalysis of the reaction: (R)-pulegone + H(+) + NADPH + O(2) = (R)-menthofuran + 2 H(2)O + NADP(+).	tmpzr1t_l9r_go_relaxed.owl	(+)-pulegone 9-hydroxylase activity|(+)-pulegone,NADPH:oxygen oxidoreductase (9-hydroxylating) activity|menthofuran synthase activity|cytochrome P450 menthofuran synthase activity|(+)-MFS activity				KEGG_REACTION:R08923|RHEA:25658|EC:1.14.14.143|MetaCyc:1.14.13.104-RXN			ai	2010-08-09T04:47:42Z					molecular_function											owl:Class	
GO:0018750	biolink:NamedThing	biuret amidohydrolase activity	Catalysis of the reaction: biuret + H2O = urea + CO2 + NH3.	tmpzr1t_l9r_go_relaxed.owl					EC:3.5.1.84|RHEA:17525|UM-BBD_reactionID:r0846									molecular_function											owl:Class	
GO:0034918	biolink:NamedThing	3-hydroxy-2-methylhexanoyl-CoA dehydrogenase activity	Catalysis of the reaction: 3-hydroxy-2-methylhexanoyl-CoA = 2-methyl-3-oxohexanoyl-CoA + 2 H+ + 2 e-.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0930									molecular_function											owl:Class	
GO:0033544	biolink:NamedThing	fatty acid beta-oxidation, unsaturated, even number, epimerase pathway	A fatty acid beta-oxidation pathway by which fatty acids having cis-double bonds on even-numbered carbons are degraded. In this pathway, the intermediate 2,4-dienoyl-CoA is converted to cis-2-enoyl-CoA through one more cycle of the core beta-oxidation pathway. Cis-2-enoyl-CoA cannot be completely degraded via the core beta-oxidation pathway because hydratation of cis-2-enoyl-CoA yields D-3-hydroxyacyl-CoA, which is not a substrate for 3-hydroxylacyl-CoA dehydrogenase. Cis-2-enoyl-CoA must enter the so-called epimerase pathway, which involves converting D-3-hydroxyacyl-CoA to L-3-hydroxyacyl-CoA by 3-hydroxylacyl-CoA epimerase or by two stereo-specific enoyl-CoA hydratases. L-3-hydroxyacyl-CoA then returns to the core beta-oxidation pathway. Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and ends when only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively).	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0031757	biolink:NamedThing	Edg-4 lysophosphatidic acid receptor binding	Binding to an Edg-4 lysophosphatidic acid receptor.	tmpzr1t_l9r_go_relaxed.owl	LPA2 receptor binding|Edg-4 lysophosphatidic acid receptor ligand													molecular_function											owl:Class	
GO:0090426	biolink:NamedThing	actin filament bundle convergence	A process of actin filament bundle distribution that results in the compaction of actin filaments.	tmpzr1t_l9r_go_relaxed.owl								tb	2012-05-04T09:33:09Z					biological_process											owl:Class	
GO:0045853	biolink:NamedThing	negative regulation of bicoid mRNA localization	Any process that stops, prevents, or reduces the frequency, rate or extent of the process in which bicoid mRNA is transported to, or maintained in, a specific location.	tmpzr1t_l9r_go_relaxed.owl	down regulation of bicoid mRNA localization|downregulation of bicoid mRNA localization|inhibition of bicoid mRNA localization|negative regulation of bicoid mRNA localisation|down-regulation of bicoid mRNA localization													biological_process											owl:Class	
GO:1900521	biolink:NamedThing	regulation of response to amylopectin	Any process that modulates the frequency, rate or extent of response to amylopectin.	tmpzr1t_l9r_go_relaxed.owl								tt	2012-05-02T04:13:51Z					biological_process											owl:Class	
GO:0070590	biolink:NamedThing	spore wall biogenesis	A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a spore wall. A spore wall is the specialized cell wall lying outside the cell membrane of a spore.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-04-28T01:06:10Z					biological_process											owl:Class	
GO:1990892	biolink:NamedThing	mitotic chromosome arm condensation	The cell cycle process in which chromosome arm chromatin structure is compacted prior to and during mitosis in eukaryotic cells.	tmpzr1t_l9r_go_relaxed.owl								vw	2015-11-03T14:16:59Z					biological_process											owl:Class	
GO:0044635	biolink:NamedThing	positive regulation of complement activation, alternative pathway in other organism	Any process that activates or increases the frequency, rate or extent of complement activation by the alternative pathway, in a different organism.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-07-05T04:36:11Z					biological_process											owl:Class	
GO:0032962	biolink:NamedThing	positive regulation of inositol trisphosphate biosynthetic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of inositol trisphosphate.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of inositol trisphosphate formation|positive regulation of myo-inositol trisphosphate biosynthetic process|positive regulation of inositol trisphosphate synthesis|positive regulation of inositol trisphosphate biosynthesis|positive regulation of IP3 biosynthesis|positive regulation of myo-inositol trisphosphate biosynthesis|positive regulation of inositol trisphosphate anabolism|positive regulation of IP3 biosynthetic process													biological_process											owl:Class	
GO:0061663	biolink:NamedThing	NEDD8 ligase activity	Catalysis of the transfer of NEDD8 to a substrate protein via the reaction X-NEDD8 + S --> X + S-NEDD8, where X is either an E2 or E3 enzyme, the X-NEDD8 linkage is a thioester bond, and the S-NEDD8 linkage is an isopeptide bond between the C-terminal amino acid of NEDD8 and the epsilon-amino group of lysine residues in the substrate.	tmpzr1t_l9r_go_relaxed.owl	E3							dph	2014-11-06T13:57:00Z					molecular_function											owl:Class	
GO:0002107	biolink:NamedThing	generation of mature 3'-end of 5S rRNA generated by RNA polymerase III	The removal of extra uridine residues from the 3' end of a 5S pre-rRNA generated by transcription by RNA polymerase III to generate the mature 3'-end.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0046182	biolink:NamedThing	L-idonate biosynthetic process	The chemical reactions and pathways resulting in the formation of L-idonate, the anion of idonic acid, an aldonic acid derived from L-idose, an aldohexose which is epimeric with D-glucose.	tmpzr1t_l9r_go_relaxed.owl	L-idonate synthesis|L-idonate anabolism|L-idonate formation|L-idonate biosynthesis													biological_process											owl:Class	
GO:0019523	biolink:NamedThing	L-idonate metabolic process	The chemical reactions and pathways involving L-idonate, the anion of idonic acid, an aldonic acid derived from L-idose, an aldohexose which is epimeric with D-glucose.	tmpzr1t_l9r_go_relaxed.owl	L-idonate metabolism				MetaCyc:IDNCAT-PWY									biological_process											owl:Class	
GO:2000101	biolink:NamedThing	regulation of mammary stem cell proliferation	Any process that modulates the frequency, rate or extent of mammary stem cell proliferation.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-09-14T06:10:32Z					biological_process											owl:Class	
GO:0038153	biolink:NamedThing	CCL2-activated CCR4 signaling pathway	A series of molecular signals initiated by the binding of the C-C chemokine CCL2 to a C-C chemokine type 4 receptor (CCR4) on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.	tmpzr1t_l9r_go_relaxed.owl	CCL2/CCR4 signaling pathway							bf	2012-05-11T11:44:48Z					biological_process											owl:Class	
GO:1901445	biolink:NamedThing	regulation of response to propan-1-ol	Any process that modulates the frequency, rate or extent of response to propan-1-ol.	tmpzr1t_l9r_go_relaxed.owl								tt	2012-10-02T14:12:46Z					biological_process											owl:Class	
GO:0009625	biolink:NamedThing	response to insect	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from an insect.	tmpzr1t_l9r_go_relaxed.owl	response to insects											GO:0043019		biological_process											owl:Class	
GO:0060622	biolink:NamedThing	regulation of ascospore wall beta-glucan biosynthetic process	Any process that modulates the rate, frequency or extent of ascospore wall beta-glucan biosynthetic process, the chemical reactions and pathways resulting in the formation of beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds, found in the walls of ascospores.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-05-18T02:01:26Z					biological_process											owl:Class	
GO:0061885	biolink:NamedThing	positive regulation of mini excitatory postsynaptic potential	Any process that increases the frequency, rate or extent of mini excitatory postsynaptic potential. Mini excitatory postsynaptic potential is a process that leads to a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell, induced by the spontaneous release of a single vesicle of an excitatory neurotransmitter into the synapse.	tmpzr1t_l9r_go_relaxed.owl								dph	2017-05-30T15:46:16Z					biological_process											owl:Class	
GO:0071614	biolink:NamedThing	linoleic acid epoxygenase activity	Catalysis of an NADPH- and oxygen-dependent reaction that converts linoleic acid to a cis-epoxyoctadecenoic acid.	tmpzr1t_l9r_go_relaxed.owl	linoleic acid monooxygenase activity							mah	2010-02-05T06:05:22Z					molecular_function											owl:Class	
GO:0046838	biolink:NamedThing	phosphorylated carbohydrate dephosphorylation	The process of removing a phosphate group from a phosphorylated carbohydrate, any organic compound based on the general formula Cx(H2O)y with a phosphate group attached to it.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0050564	biolink:NamedThing	N-(5-amino-5-carboxypentanoyl)-L-cysteinyl-D-valine synthase activity	Catalysis of the reaction: L-2-aminoadipate + L-cysteine + L-valine + 3 ATP + H(2)O = N-[(5S)-5-amino-5-carboxypentanoyl]-L-cysteinyl-D-valine + 3 AMP + 3 diphosphate + 6 H(+).	tmpzr1t_l9r_go_relaxed.owl	ACV synthetase activity|L-delta-(alpha-aminoadipoyl)-L-cysteinyl-D-valine synthetase activity|L-2-aminohexanedioate:L-cysteine:L-valine ligase (AMP-forming, valine-inverting)|L-alpha-aminoadipyl-cysteinyl-valine synthetase activity				EC:6.3.2.26|KEGG_REACTION:R04870|RHEA:23196|MetaCyc:6.3.2.26-RXN									molecular_function											owl:Class	
GO:1904052	biolink:NamedThing	negative regulation of protein targeting to vacuole involved in autophagy	Any process that stops, prevents or reduces the frequency, rate or extent of protein targeting to vacuole involved in autophagy.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of protein targeting to vacuole involved in autophagy|downregulation of protein targeting to vacuole involved in autophagy|down regulation of protein targeting to vacuole involved in autophagy|inhibition of protein targeting to vacuole involved in autophagy					An example of this is SMURF1 in human (UniProt symbol Q9HCE7) in PMID:22020285 (inferred from mutant phenotype).		pad	2015-03-17T13:54:22Z					biological_process											owl:Class	
GO:0006936	biolink:NamedThing	muscle contraction	A process in which force is generated within muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Muscle_contraction									biological_process											owl:Class	
GO:0042767	biolink:NamedThing	ecdysteroid 22-hydroxylase activity	Catalysis of the hydroxylation of an ecdysteroid at carbon position 22.	tmpzr1t_l9r_go_relaxed.owl						Note that in the ecdysteroidogenic pathway, this activity catalyzes the conversion of 2,22-dideoxyecdysone (ketotriol) to 2-deoxyecdysone.								molecular_function											owl:Class	
GO:0047890	biolink:NamedThing	flavanone 4-reductase activity	Catalysis of the reaction: (2S)-flavan-4-ol + NADP+ = (2S)-flavanone + NADPH.	tmpzr1t_l9r_go_relaxed.owl	(2S)-flavan-4-ol:NADP+ 4-oxidoreductase activity|flavonone 4-reductase activity				MetaCyc:FLAVANONE-4-REDUCTASE-RXN|RHEA:11228|EC:1.1.1.234									molecular_function											owl:Class	
GO:0045336	biolink:NamedThing	clathrin-coated phagocytic vesicle	A clathrin-coated, membrane-bounded intracellular vesicle that arises from the ingestion of particulate material by phagocytosis.	tmpzr1t_l9r_go_relaxed.owl	clathrin-coated phagosome													cellular_component											owl:Class	
GO:0045334	biolink:NamedThing	clathrin-coated endocytic vesicle	A clathrin-coated, membrane-bounded intracellular vesicle formed by invagination of the plasma membrane around an extracellular substance.	tmpzr1t_l9r_go_relaxed.owl					NIF_Subcellular:sao1243595998									cellular_component											owl:Class	
GO:0045513	biolink:NamedThing	interleukin-27 binding	Binding to interleukin-27.	tmpzr1t_l9r_go_relaxed.owl	IL-27 binding													molecular_function											owl:Class	
GO:1990232	biolink:NamedThing	phosphomannomutase complex	A protein complex capable of phosphomannomutase activity.	tmpzr1t_l9r_go_relaxed.owl	PMM-2 complex|PMM-1 dimer|PMM-1 complex|PMM-2 dimer							bhm	2013-11-12T13:05:54Z					cellular_component											owl:Class	
GO:1990233	biolink:NamedThing	intramolecular phosphotransferase complex	A protein complex capable of catalyzing the transfer of a phosphate group from one position to another within a single molecule.	tmpzr1t_l9r_go_relaxed.owl								bhm	2013-11-12T13:10:12Z					cellular_component											owl:Class	
GO:0036449	biolink:NamedThing	microtubule minus-end	The end of a microtubule that does not preferentially grow (polymerize).	tmpzr1t_l9r_go_relaxed.owl	microtubule minus end							bf	2013-10-31T13:26:51Z					cellular_component											owl:Class	
GO:0098026	biolink:NamedThing	virus tail, tube	The internal tube of the contractile tails of some viruses. The virus tail tube is the channel for DNA ejection into the host cytoplasm.	tmpzr1t_l9r_go_relaxed.owl	bacteriophage tail tube					Applies in particular the Myoviridae bacteriophages.		bm	2012-07-19T14:21:28Z					cellular_component											owl:Class	
GO:0019337	biolink:NamedThing	tetrachloroethylene catabolic process	The chemical reactions and pathways resulting in the breakdown of tetrachloroethylene, a derivative of ethene with the hydrogen atoms replaced by chlorines.	tmpzr1t_l9r_go_relaxed.owl	tetrachloroethylene degradation|tetrachloroethylene breakdown|tetrachloroethene catabolism|tetrachloroethene catabolic process|tetrachloroethylene catabolism				MetaCyc:PCEDEG-PWY									biological_process											owl:Class	
GO:0042205	biolink:NamedThing	chlorinated hydrocarbon catabolic process	The chemical reactions and pathways resulting in the breakdown of chlorinated hydrocarbons, compounds derived from hydrocarbons by replacing one or more hydrogen atoms with chlorine atoms.	tmpzr1t_l9r_go_relaxed.owl	chlorinated hydrocarbon catabolism|chlorinated hydrocarbon degradation|chlorinated hydrocarbon breakdown													biological_process											owl:Class	
GO:2001269	biolink:NamedThing	positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway	Any process that activates or increases the frequency, rate or extent of cysteine-type endopeptidase activity involved in apoptotic signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of initiator caspase activity|positive regulation of cysteine-type endopeptidase activity involved in apoptotic signalling pathway							pr	2011-12-13T07:56:26Z					biological_process											owl:Class	
GO:0099612	biolink:NamedThing	protein localization to axon	A process in which a protein is transported to or maintained in a location within an axon.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0102535	biolink:NamedThing	ladanein 6-O-methyltransferase activity	Catalysis of the reaction: ladanein + S-adenosyl-L-methionine  <=> H+ + salvigenin + S-adenosyl-L-homocysteine.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-14752									molecular_function											owl:Class	
GO:0015013	biolink:NamedThing	heparan sulfate proteoglycan biosynthetic process, linkage to polypeptide	The polymerization of one or more heparan sulfate chains via a xylose link onto serine residues in the core protein of a proteoglycan.	tmpzr1t_l9r_go_relaxed.owl	heparin proteoglycan biosynthetic process, linkage to polypeptide|heparan sulphate proteoglycan biosynthetic process, linkage to polypeptide|heparan sulfate proteoglycan formation, linkage to polypeptide|heparan sulfate proteoglycan synthesis, linkage to polypeptide|heparan sulfate proteoglycan anabolism, linkage to polypeptide|heparan sulphate proteoglycan biosynthesis, linkage to polypeptide													biological_process											owl:Class	
GO:0018242	biolink:NamedThing	protein O-linked glycosylation via serine	The glycosylation of protein via the O3 atom of peptidyl-serine, forming O3-glycosyl-L-serine; the most common forms are N-acetylgalactosaminyl, mannosyl, galactosyl, and xylosyl serine.	tmpzr1t_l9r_go_relaxed.owl	protein amino acid O-linked glycosylation via serine				RESID:AA0154									biological_process											owl:Class	
GO:0050599	biolink:NamedThing	deacetoxycephalosporin-C synthase activity	Catalysis of the reaction: 2-oxoglutarate + O(2) + penicillin N = CO(2) + deacetoxycephalosporin C + H(2)O + succinate.	tmpzr1t_l9r_go_relaxed.owl	penicillin N expandase activity|penicillin-N,2-oxoglutarate:oxygen oxidoreductase (ring-expanding)|deacetoxycephalosporin C synthetase activity|DAOC synthase activity|DAOCS activity|expandase activity				KEGG_REACTION:R05301|RHEA:20748|MetaCyc:1.14.20.1-RXN|EC:1.14.20.1							GO:0045441		molecular_function											owl:Class	
GO:0004829	biolink:NamedThing	threonine-tRNA ligase activity	Catalysis of the reaction: ATP + L-threonine + tRNA(Thr) = AMP + diphosphate + L-threonyl-tRNA(Thr).	tmpzr1t_l9r_go_relaxed.owl	TRS|threonine-transfer ribonucleate synthetase activity|L-threonine:tRNAThr ligase (AMP-forming)|threonyl-transfer RNA synthetase activity|threonyl-transfer ribonucleic acid synthetase activity|threonyl ribonucleic synthetase activity|threonyl-tRNA synthetase activity|threonine translase activity|threonyl-transfer ribonucleate synthetase activity				MetaCyc:THREONINE--TRNA-LIGASE-RXN|EC:6.1.1.3|Reactome:R-HSA-380201|Reactome:R-HSA-380002|RHEA:24624									molecular_function											owl:Class	
GO:0032823	biolink:NamedThing	regulation of natural killer cell differentiation	Any process that modulates the frequency, rate or extent of natural killer cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	regulation of natural killer cell development|regulation of NK cell differentiation					Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.								biological_process											owl:Class	
GO:0047118	biolink:NamedThing	2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate reductase activity	Catalysis of the reaction: 2,6-dioxo-6-phenylhexanoate + NADP(+) = 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate + H(+) + NADPH.	tmpzr1t_l9r_go_relaxed.owl	2,6-dioxo-6-phenylhexanoate:NADP+ delta2-oxidoreductase activity|2-hydroxy-6-oxo-phenylhexa-2,4-dienoate (reduced nicotinamide adenine dinucleotide phosphate) reductase activity				KEGG_REACTION:R03463|MetaCyc:1.3.1.40-RXN|EC:1.3.1.40|RHEA:24268									molecular_function											owl:Class	
GO:0032828	biolink:NamedThing	positive regulation of natural killer cell differentiation involved in immune response	Any process that activates or increases the frequency, rate or extent of natural killer cell differentiation as part of an immune response.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of natural killer cell development involved in immune response|stimulation of natural killer cell differentiation during immune response|upregulation of natural killer cell differentiation during immune response|positive regulation of NK cell differentiation during immune response|activation of natural killer cell differentiation during immune response|up regulation of natural killer cell differentiation during immune response|positive regulation of natural killer cell differentiation during immune response|up-regulation of natural killer cell differentiation during immune response					Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.								biological_process											owl:Class	
GO:1902011	biolink:NamedThing	poly(ribitol phosphate) teichoic acid metabolic process	The chemical reactions and pathways involving poly(ribitol phosphate) teichoic acid.	tmpzr1t_l9r_go_relaxed.owl	poly(ribitol phosphate) teichoic acid metabolism							tb	2013-03-22T15:43:36Z					biological_process											owl:Class	
GO:0097016	biolink:NamedThing	L27 domain binding	Binding to a L27 domain of a protein. L27 is composed of conserved negatively charged amino acids and a conserved aromatic amino acid. L27 domains can assemble proteins involved in signaling and establishment and maintenance of cell polarity into complexes by interacting in a heterodimeric manner.	tmpzr1t_l9r_go_relaxed.owl								pr	2011-03-23T02:17:51Z					molecular_function											owl:Class	
GO:2000513	biolink:NamedThing	positive regulation of granzyme A production	Any process that activates or increases the frequency, rate or extent of granzyme A production.	tmpzr1t_l9r_go_relaxed.owl								ebc	2011-03-22T10:31:36Z					biological_process											owl:Class	
GO:0035373	biolink:NamedThing	chondroitin sulfate proteoglycan binding	Binding to a chondroitin sulfate proteoglycan, any proteoglycan containing chondroitin sulfate as the glycosaminoglycan carbohydrate unit.	tmpzr1t_l9r_go_relaxed.owl								bf	2010-03-12T10:23:55Z					molecular_function											owl:Class	
GO:0043394	biolink:NamedThing	proteoglycan binding	Binding to a proteoglycan, any glycoprotein in which the carbohydrate units are glycosaminoglycans.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0021620	biolink:NamedThing	hypoglossal nerve formation	The process that gives rise to the hypoglossal nerve. This process pertains to the initial formation of a structure from unspecified parts. This motor nerve innervates all the intrinsic and all but one of the extrinsic muscles of the tongue.	tmpzr1t_l9r_go_relaxed.owl	CN XII biosynthesis|CN XII formation													biological_process											owl:Class	
GO:0043733	biolink:NamedThing	DNA-3-methylbase glycosylase activity	Catalysis of the reaction: DNA containing 3-methylbase + H2O = DNA with abasic site + 3-methylbase. This reaction is the hydrolysis of DNA by cleavage of the N-C1' glycosidic bond between the damaged DNA 3-methylpurine or 3-methylpyrimidine base and the deoxyribose sugar to remove the methylated base, leaving an apurinic or apyrimidinic site.	tmpzr1t_l9r_go_relaxed.owl	DNA-3-methyladenine glycosylase III|MagIII|Mag III													molecular_function											owl:Class	
GO:0003905	biolink:NamedThing	alkylbase DNA N-glycosylase activity	Catalysis of the reaction: DNA with alkylated base + H2O = DNA with abasic site + alkylated base. This reaction is the hydrolysis of DNA by cleavage of the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar to remove an alkylated base, leaving an apyrimidinic or apurinic site.	tmpzr1t_l9r_go_relaxed.owl	DNA-3-methyladenine glycosylase II|DNA-3-methyladenine glycosidase II activity|DNA glycosidase II activity|3-methyladenine DNA glycosylase II|deoxyribonucleate 3-methyladenine glycosidase II|AlkA|alkylated-DNA glycohydrolase (releasing methyladenine and methylguanine)|alkylbase DNA glycosidase activity				MetaCyc:3.2.2.21-RXN|EC:3.2.2.21							GO:0004036		molecular_function											owl:Class	
GO:0102300	biolink:NamedThing	linoleate 9R-lipoxygenase activity	Catalysis of the reaction: linoleate + O2 = 9(R)-HPODE.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-12760|EC:1.13.11.61|RHEA:31691									molecular_function											owl:Class	
GO:0045552	biolink:NamedThing	dihydrokaempferol 4-reductase activity	Catalysis of the reaction: cis-3,4-leucopelargonidin + NADP+ = (+)-dihydrokaempferol + NADPH + H+.	tmpzr1t_l9r_go_relaxed.owl	cis-3,4-leucopelargonidin:NADP+ 4-oxidoreductase activity|dihydroflavonol 4-reductase activity|dihydroquercetin reductase activity|dihydromyricetin reductase activity|dihydroflavanol 4-reductase activity|NADPH-dihydromyricetin reductase activity				MetaCyc:DIHYDROKAEMPFEROL-4-REDUCTASE-RXN|RHEA:23016|EC:1.1.1.219									molecular_function											owl:Class	
GO:0031879	biolink:NamedThing	type 2 somatostatin receptor binding	Binding to a type 2 somatostatin receptor.	tmpzr1t_l9r_go_relaxed.owl	type 2 somatostatin receptor ligand													molecular_function											owl:Class	
GO:0031877	biolink:NamedThing	somatostatin receptor binding	Binding to a somatostatin receptor.	tmpzr1t_l9r_go_relaxed.owl	somatostatin receptor ligand													molecular_function											owl:Class	
GO:0000736	biolink:NamedThing	double-strand break repair via single-strand annealing, removal of nonhomologous ends	During DSBR via single-strand annealing, the removal of nonhomologous sequences at the broken 3' single-strand DNA end before DNA repair synthesis can occur.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0060496	biolink:NamedThing	mesenchymal-epithelial cell signaling involved in lung development	Any process that mediates the transfer of information from a mesenchymal cell to an epithelial cell and contributes to the development of the lung.	tmpzr1t_l9r_go_relaxed.owl	mesenchymal-epithelial cell signalling involved in lung development													biological_process											owl:Class	
GO:2001292	biolink:NamedThing	codeine catabolic process	The chemical reactions and pathways resulting in the breakdown of codeine, an alkaloid found in the opium poppy, Papaver somniferum var. album. Codeine has analgesic, anti-tussive and anti-diarrhoeal properties.	tmpzr1t_l9r_go_relaxed.owl	codeine catabolism|codeine degradation|codeine breakdown							pr	2012-02-14T01:10:09Z					biological_process											owl:Class	
GO:0070540	biolink:NamedThing	stearic acid binding	Binding to stearic acid, the 18-carbon saturated fatty acid octadecanoic acid.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0016966	biolink:NamedThing	nitric oxide reductase activity	Catalysis of the reaction: H(2)O + 2 ferricytochrome c + nitrous oxide = 2 H(+) + 2 ferrocytochrome c + 2 nitric oxide.	tmpzr1t_l9r_go_relaxed.owl	cytochrome bc nitric oxide reductase activity|nitrous-oxide:(acceptor) oxidoreductase (NO-forming)|nitrogen oxide reductase activity|CYP55|P450 nitric oxide reductase activity|P450nor|nitrous-oxide:acceptor oxidoreductase (NO-forming)|nitric-oxide reductase activity				MetaCyc:NITRIC-OXIDE-REDUCTASE-RXN|RHEA:30211|KEGG_REACTION:R00294|EC:1.7.2.5							GO:0016968|GO:0016967		molecular_function											owl:Class	
GO:2000723	biolink:NamedThing	negative regulation of cardiac vascular smooth muscle cell differentiation	Any process that stops, prevents or reduces the frequency, rate or extent of cardiac vascular smooth muscle cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of heart vascular smooth muscle cell differentiation							vk	2011-06-08T08:48:01Z					biological_process											owl:Class	
GO:2000722	biolink:NamedThing	regulation of cardiac vascular smooth muscle cell differentiation	Any process that modulates the frequency, rate or extent of cardiac vascular smooth muscle cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	regulation of heart vascular smooth muscle cell differentiation							vk	2011-06-08T08:47:58Z					biological_process											owl:Class	
GO:0036030	biolink:NamedThing	protein C inhibitor-plasma kallikrein complex	A heterodimeric protein complex that contains protein C inhibitor (SERPINA5) and plasma kallikrein (KLK1B); formation of the complex inhibits the serine protease activity of plasma kallikrein.	tmpzr1t_l9r_go_relaxed.owl	plasma serine protease inhibitor-plasma kallikrein complex|PCI-plasma kallikrein complex|protein C inhibitor-KLKB1 complex|SERPINA5-plasma kallikrein complex|serpin A5-plasma kallikrein complex							bf	2011-10-19T02:05:46Z					cellular_component											owl:Class	
GO:0016286	biolink:NamedThing	small conductance calcium-activated potassium channel activity	Enables the transmembrane transfer of potassium by a channel with a unit conductance of 2 to 20 picoSiemens that opens in response to stimulus by internal calcium ions. Small conductance calcium-activated potassium channels are more sensitive to calcium than are large conductance calcium-activated potassium channels. Transport by a channel involves catalysis of facilitated diffusion of a solute (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel, without evidence for a carrier-mediated mechanism.	tmpzr1t_l9r_go_relaxed.owl	small conductance KCa channels|SK KCa channels|SK calcium-activated potassium channel activity													molecular_function											owl:Class	
GO:0015269	biolink:NamedThing	calcium-activated potassium channel activity	Enables the calcium concentration-regulatable energy-independent passage of potassium ions across a lipid bilayer down a concentration gradient.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0061188	biolink:NamedThing	negative regulation of ribosomal DNA heterochromatin assembly	Any process that decreases the rate, frequency, or extent of the repression of assembly of rDNA heterochromatin.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of chromatin silencing at rDNA	https://github.com/geneontology/go-ontology/issues/19238						dph	2010-07-14T09:07:59Z					biological_process											owl:Class	
GO:1903933	biolink:NamedThing	negative regulation of DNA primase activity	Any process that stops, prevents or reduces the frequency, rate or extent of DNA primase activity.	tmpzr1t_l9r_go_relaxed.owl	downregulation of DNA primase activity|down regulation of DNA primase activity|inhibition of DNA primase activity|down-regulation of DNA primase activity							mah	2015-02-12T14:28:36Z					biological_process											owl:Class	
GO:1900483	biolink:NamedThing	regulation of protein targeting to vacuolar membrane	Any process that modulates the frequency, rate or extent of protein targeting to vacuolar membrane.	tmpzr1t_l9r_go_relaxed.owl								al	2012-05-02T10:13:23Z					biological_process											owl:Class	
GO:0060802	biolink:NamedThing	epiblast cell-extraembryonic ectoderm cell signaling involved in anterior/posterior axis specification	Any process that mediates the transfer of information from an epiblast cell to an extraembryonic ectoderm cell that contributes to the specification of the anterior/posterior axis.	tmpzr1t_l9r_go_relaxed.owl	epiblast cell-extraembryonic ectoderm cell signalling involved in anterior/posterior axis specification							dph	2009-08-06T01:36:13Z					biological_process											owl:Class	
GO:0061199	biolink:NamedThing	striated muscle contraction involved in embryonic body morphogenesis	The process in which force is generated within striated embryonic muscle tissue, resulting in a contraction of the muscle that contributes to the formation of an embryo's characteristic body morphology.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-07-28T04:07:23Z					biological_process											owl:Class	
GO:1903506	biolink:NamedThing	regulation of nucleic acid-templated transcription	Any process that modulates the frequency, rate or extent of nucleic acid-templated transcription.	tmpzr1t_l9r_go_relaxed.owl								pr	2014-10-01T14:44:47Z					biological_process											owl:Class	
GO:0016004	biolink:NamedThing	phospholipase activator activity	Increases the activity of a phospholipase, an enzyme that catalyzes of the hydrolysis of a glycerophospholipid.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0070155	biolink:NamedThing	mitochondrial methionyl-tRNA aminoacylation	The process of coupling methionine to methionyl-tRNA in a mitochondrion, catalyzed by methionyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0006431	biolink:NamedThing	methionyl-tRNA aminoacylation	The process of coupling methionine to methionyl-tRNA, catalyzed by methionyl-tRNA synthetase. The methionyl-tRNA synthetase is a  class-I synthetase. The activated amino acid is transferred to the 2'-OH group of a methionine-accetping tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0008474	biolink:NamedThing	palmitoyl-(protein) hydrolase activity	Catalysis of the reaction: palmitoyl-protein + H2O = palmitate + protein.	tmpzr1t_l9r_go_relaxed.owl	palmitoyl-[protein] hydrolase|palmitoyl-protein thioesterase activity|palmitoyl-protein hydrolase activity|palmitoyl-protein thiolesterase activity				Reactome:R-HSA-5690517|EC:3.1.2.22|Reactome:R-HSA-9647994|Reactome:R-HSA-8933328|RHEA:19233|Reactome:R-HSA-203613|MetaCyc:3.1.2.22-RXN									molecular_function											owl:Class	
GO:0071672	biolink:NamedThing	negative regulation of smooth muscle cell chemotaxis	Any process that stops, prevents, or reduces the frequency, rate, or extent of smooth muscle cell chemotaxis.	tmpzr1t_l9r_go_relaxed.owl	downregulation of smooth muscle cell chemotaxis|down regulation of smooth muscle cell chemotaxis|inhibition of smooth muscle cell chemotaxis|down-regulation of smooth muscle cell chemotaxis							mah	2010-02-16T01:44:28Z					biological_process											owl:Class	
GO:0033572	biolink:NamedThing	transferrin transport	The directed movement of transferrin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	melanotransferrin transport													biological_process											owl:Class	
GO:0150190	biolink:NamedThing	negative regulation of interleukin-32 production	Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-32 production.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of interleukin-32 secretion|negative regulation of interleukin-32 biosynthetic process							bc	2020-02-21T10:31:53Z			GO:0150193		biological_process											owl:Class	
GO:0150189	biolink:NamedThing	regulation of interleukin-32 production	Any process that modulates the frequency, rate or extent of interleukin-32 production.	tmpzr1t_l9r_go_relaxed.owl	regulation of interleukin-32 secretion|regulation of interleukin-32 biosynthetic process							bc	2020-02-21T10:28:36Z			GO:0150192		biological_process											owl:Class	
GO:0009724	biolink:NamedThing	detection of abscisic acid stimulus	The series of events in which an abscisic acid stimulus is received by a cell and converted into a molecular signal.	tmpzr1t_l9r_go_relaxed.owl	perception of abscisic acid stimulus													biological_process											owl:Class	
GO:0050116	biolink:NamedThing	N,N-dimethylformamidase activity	Catalysis of the reaction: N,N-dimethylformamide + H(2)O = dimethylamine + formate.	tmpzr1t_l9r_go_relaxed.owl	DMFase activity|N,N-dimethylformamide amidohydrolase activity|dimethylformamidase activity				KEGG_REACTION:R02509|MetaCyc:NN-DIMETHYLFORMAMIDASE-RXN|EC:3.5.1.56|RHEA:19517									molecular_function											owl:Class	
GO:0072552	biolink:NamedThing	monoferuloyl di-(hydroxyferuloyl) spermidine meta-hydroxylase activity	Catalysis of the reaction: monoferuloyl di-(hydroxyferuloyl) spermidine + NADPH + O2 = tri-(hydroxyferuloyl) spermidine + NADP+ + H2O.	tmpzr1t_l9r_go_relaxed.owl								mah	2011-01-25T03:15:31Z					molecular_function											owl:Class	
GO:1990280	biolink:NamedThing	RNA localization to chromatin	A process in which RNA is transported to and maintained in a part of a chromosome that is organized into chromatin.	tmpzr1t_l9r_go_relaxed.owl	RNA localisation to chromatin							mah	2014-01-30T15:55:34Z					biological_process											owl:Class	
GO:2000685	biolink:NamedThing	positive regulation of cellular response to X-ray	Any process that activates or increases the frequency, rate or extent of cellular response to X-ray.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of cellular response to X-ray radiation stimulus							yaf	2011-05-10T01:40:49Z					biological_process											owl:Class	
GO:0036386	biolink:NamedThing	bacterial nucleoid DNA packaging	Compaction of DNA in a bacterial nucleoid into a compact structure. Often achieved by DNA supercoiling.	tmpzr1t_l9r_go_relaxed.owl	nucleoid compaction|prokaryotic DNA condensation|chromosomal compaction							bf	2013-05-30T10:41:08Z					biological_process											owl:Class	
GO:0045721	biolink:NamedThing	negative regulation of gluconeogenesis	Any process that stops, prevents, or reduces the frequency, rate or extent of gluconeogenesis.	tmpzr1t_l9r_go_relaxed.owl	inhibition of gluconeogenesis|down regulation of gluconeogenesis|down-regulation of gluconeogenesis|downregulation of gluconeogenesis													biological_process											owl:Class	
GO:0032998	biolink:NamedThing	Fc-epsilon receptor I complex	A protein complex composed of an Fc-epsilon RI alpha chain and an Fc-epsilon RI gamma chain dimer with or without an Fc-episilon RI beta chain and additional signaling components. The complex functions primarily as an activating receptor for IgE.	tmpzr1t_l9r_go_relaxed.owl	immunoglobulin E receptor complex|IgE receptor complex|FceRI complex													cellular_component											owl:Class	
GO:0035319	biolink:NamedThing	imaginal disc-derived wing hair elongation	Growth of a prehair in the approximately 10 hour period following its emergence from an epidermal cell in an imaginal disc-derived wing. Prehair elongation is guided and/or driven by the polymerization of actin filaments and the orderly crosslinking of filaments into bundles.	tmpzr1t_l9r_go_relaxed.owl	wing prehair extension|wing hair elongation													biological_process											owl:Class	
GO:0070906	biolink:NamedThing	aspartate:alanine antiporter activity	Catalysis of the reaction: aspartate(out) + alanine(in) = aspartate(in) + alanine(out).	tmpzr1t_l9r_go_relaxed.owl	aspartate/alanine antiporter activity|aspartate-alanine antiporter activity				RHEA:33139			mah	2009-09-04T03:44:15Z					molecular_function											owl:Class	
GO:0097739	biolink:NamedThing	negative regulation of ferrichrome biosynthetic process in response to iron	Any process that stops, prevents or reduces the rate of ferrichrome biosynthetic process in response to an iron stimulus.	tmpzr1t_l9r_go_relaxed.owl								pr	2016-10-18T17:00:24Z					biological_process											owl:Class	
GO:0034868	biolink:NamedThing	2,4,4-trimethyl-3-hydroxypentanoyl-CoA dehydrogenase activity	Catalysis of the reaction: 2,4,4-trimethyl-3-hydroxypentanoyl-CoA = 2,4,4-trimethyl-3-oxopentanoyl-CoA + 2 H+ + 2 e-.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r1273									molecular_function											owl:Class	
GO:0021993	biolink:NamedThing	initiation of neural tube closure	The process in which closure points are established at multiple points and along the neural rostrocaudal axis.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0032052	biolink:NamedThing	bile acid binding	Binding to a bile acid, a steroid carboxylic acids occurring in bile.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1901788	biolink:NamedThing	benzoyl-CoA catabolic process	The chemical reactions and pathways resulting in the breakdown of benzoyl-CoA.	tmpzr1t_l9r_go_relaxed.owl	benzoyl-CoA catabolism|benzoyl-CoA degradation|benzoyl-CoA breakdown							yaf	2013-01-16T11:13:59Z					biological_process											owl:Class	
GO:0020037	biolink:NamedThing	heme binding	Binding to a heme, a compound composed of iron complexed in a porphyrin (tetrapyrrole) ring.	tmpzr1t_l9r_go_relaxed.owl	haem binding													molecular_function											owl:Class	
GO:0044691	biolink:NamedThing	tooth eruption	The tooth development process in which the teeth enter the mouth and become visible.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Tooth_eruption			jl	2012-08-15T14:58:17Z					biological_process											owl:Class	
GO:0007214	biolink:NamedThing	gamma-aminobutyric acid signaling pathway	The series of molecular signals generated by the binding of gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms, to a cell surface receptor.	tmpzr1t_l9r_go_relaxed.owl	4-aminobutyrate signaling pathway|4-aminobutanoate signalling pathway|GABA signaling pathway|4-aminobutanoate signaling pathway|4-aminobutyrate signalling pathway|gamma-aminobutyric acid signalling pathway|GABA signalling pathway													biological_process											owl:Class	
GO:0046105	biolink:NamedThing	thymidine biosynthetic process	The chemical reactions and pathways resulting in the formation of thymidine, deoxyribosylthymine thymine 2-deoxyriboside, a deoxynucleoside very widely distributed but occurring almost entirely as phosphoric esters in deoxynucleotides and deoxyribonucleic acid, DNA.	tmpzr1t_l9r_go_relaxed.owl	deoxyribosylthymine biosynthetic process|thymidine synthesis|thymidine formation|thymidine biosynthesis|deoxyribosylthymine biosynthesis|thymidine anabolism													biological_process											owl:Class	
GO:0008679	biolink:NamedThing	2-hydroxy-3-oxopropionate reductase activity	Catalysis of the reaction: (R)-glycerate + NADP+ = 2-hydroxy-3-oxopropanoate + NADPH + H+.	tmpzr1t_l9r_go_relaxed.owl	tartronate semialdehyde reductase (NADPH) activity|(R)-glycerate:NAD(P)+ oxidoreductase activity				EC:1.1.1.60|MetaCyc:TSA-REDUCT-RXN|RHEA:18841									molecular_function											owl:Class	
GO:0097630	biolink:NamedThing	intrinsic component of omegasome membrane	The component of the omegasome membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.	tmpzr1t_l9r_go_relaxed.owl	intrinsic to omegasome membrane													cellular_component											owl:Class	
GO:0015829	biolink:NamedThing	valine transport	The directed movement of valine, 2-amino-3-methylbutanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	L-valine transport													biological_process											owl:Class	
GO:0005545	biolink:NamedThing	1-phosphatidylinositol binding	Binding to a phosphatidylinositol, a glycophospholipid with its sn-glycerol 3-phosphate residue is esterified to the 1-hydroxyl group of 1D-myo-inositol.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0004958	biolink:NamedThing	prostaglandin F receptor activity	Combining with prostaglandin F (PGF (2-alpha)) to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	PGF receptor activity|PGF(2-alpha) receptor activity													molecular_function											owl:Class	
GO:1901394	biolink:NamedThing	positive regulation of transforming growth factor beta1 activation	Any process that activates or increases the frequency, rate or extent of transforming growth factor beta1 activation.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of latent-TGF-beta1 activation|up-regulation of transforming growth factor beta1 activation|activation of TGFB1 activation|positive regulation of L-TGF-beta 1 activation|upregulation of TGFbeta 1 activation|upregulation of transforming growth factor beta1 activation|up regulation of TGFB1 activation|up regulation of TGFbeta 1 activation|positive regulation of TGFbeta 1 activation|upregulation of latent-TGF-beta1 activation|positive regulation of TGF-beta 1 activation|up regulation of transforming growth factor-beta1 activation|upregulation of transforming growth factor-beta1 activation|upregulation of TGF-beta 1 activation|up regulation of L-TGF-beta 1 activation|activation of TGFbeta 1 activation|up-regulation of L-TGF-beta 1 activation|activation of TGF-beta 1 activation|up-regulation of TGFbeta 1 activation|up-regulation of transforming growth factor-beta1 activation|positive regulation of latent-TGF-beta1 activation|upregulation of L-TGF-beta 1 activation|upregulation of TGFB1 activation|positive regulation of transforming growth factor-beta1 activation|activation of transforming growth factor beta1 activation|activation of transforming growth factor-beta1 activation|up-regulation of TGFB1 activation|positive regulation of TGFB1 activation|up regulation of TGF-beta 1 activation|activation of latent-TGF-beta1 activation|up regulation of transforming growth factor beta1 activation|activation of L-TGF-beta 1 activation|up-regulation of TGF-beta 1 activation|up regulation of latent-TGF-beta1 activation							bf	2012-10-01T10:41:33Z					biological_process											owl:Class	
GO:0016116	biolink:NamedThing	carotenoid metabolic process	The chemical reactions and pathways involving carotenoids, tetraterpenoid compounds in which two units of 4 isoprenoid residues joined head-to-tail are themselves joined tail-to-tail.	tmpzr1t_l9r_go_relaxed.owl	carotenoid metabolism													biological_process											owl:Class	
GO:0043510	biolink:NamedThing	activin B complex	A nonsteroidal regulator, composed of two covalently linked inhibin beta-B subunits (sometimes known as activin beta-B or activin/inhibin beta-B).	tmpzr1t_l9r_go_relaxed.owl						Note that the actions of the activin complex are the opposite of those of the inhibin complex, which is a dimer of an inhibin beta-A or inhibin beta-B subunit and a inhibin alpha subunit. See 'inhibin complex ; GO:0043511'.						GO:0048182		cellular_component											owl:Class	
GO:0080093	biolink:NamedThing	regulation of photorespiration	Any process that modulates the rate, frequency or extent of photorespiration. Photorespiration is a light-dependent catabolic process occurring concomitantly with photosynthesis in plants (especially C3 plants) whereby dioxygen (O2) is consumed and carbon dioxide (CO2) is evolved.	tmpzr1t_l9r_go_relaxed.owl								dhl	2009-04-22T04:44:48Z					biological_process											owl:Class	
GO:0090352	biolink:NamedThing	regulation of nitrate assimilation	Any process that modulates the rate, frequency, or extent of the uptake, from the environment, of nitrates, inorganic or organic salts and esters of nitric acid and the subsequent reduction of nitrate ion to other, less highly oxidized, inorganic nitrogenous substances.	tmpzr1t_l9r_go_relaxed.owl								tb	2010-06-10T04:11:13Z					biological_process											owl:Class	
GO:1990236	biolink:NamedThing	proteasome core complex import into nucleus	The directed movement of the proteasome core complex (AKA core particle (CP)) from the cytoplasm into the nucleus.	tmpzr1t_l9r_go_relaxed.owl								rb	2013-11-14T23:27:24Z					biological_process											owl:Class	
GO:0102974	biolink:NamedThing	hydroxyversicolorone reductase activity	Catalysis of the reaction: versicolorone + NADP = hydroxyversicolorone + NADPH.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-9489|RHEA:35691|EC:1.1.1.353									molecular_function											owl:Class	
GO:0019304	biolink:NamedThing	anaerobic rhamnose catabolic process	The chemical reactions and pathways resulting in the breakdown of rhamnose, the hexose 6-deoxy-L-mannose, that occurs in the absence of oxygen.	tmpzr1t_l9r_go_relaxed.owl	anaerobic rhamnose breakdown|anaerobic rhamnose degradation|anaerobic rhamnose catabolism													biological_process											owl:Class	
GO:0075046	biolink:NamedThing	positive regulation of formation by symbiont of haustorium for nutrient acquisition from host	Any process that activates or increases the frequency, rate or extent of symbiont haustorium formation for nutrient acquisition from host. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl						Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products from the symbiont involved in this process.								biological_process											owl:Class	
GO:0043782	biolink:NamedThing	cobalt-precorrin-3 C17-methyltransferase activity	Catalysis of the reaction: cobalt-precorrin 3 + S-adenosyl-L-methionine = cobalt-precorrin 4 + S-adenosyl-L-homocysteine.	tmpzr1t_l9r_go_relaxed.owl	cobalt-precorrin 3 C17-methyltransferase activity|cobalt-precorrin-3B C17-methyltransferase activity|cobalt-precorrin-3 methyltransferase|cobalt-precorrin-3 methylase				RHEA:26273|MetaCyc:RXN-8761									molecular_function											owl:Class	
GO:0016259	biolink:NamedThing	selenocysteine metabolic process	The chemical reactions and pathways involving selenocysteine, an essential component of glutathione peroxidase and some other proteins.	tmpzr1t_l9r_go_relaxed.owl	selenocysteine metabolism													biological_process											owl:Class	
GO:0039714	biolink:NamedThing	cytoplasmic viral factory	A viral factory located in the cytoplasm of a host cell.	tmpzr1t_l9r_go_relaxed.owl								bf	2013-12-19T15:16:15Z					cellular_component											owl:Class	
GO:0020004	biolink:NamedThing	symbiont-containing vacuolar space	The space between a symbiont plasma membrane and the symbiont-containing vacuole membrane.	tmpzr1t_l9r_go_relaxed.owl	symbiont-containing vacuole space|parasitophorous vacuolar space													cellular_component											owl:Class	
GO:1900212	biolink:NamedThing	negative regulation of mesenchymal cell apoptotic process involved in metanephros development	Any process that stops, prevents or reduces the frequency, rate or extent of mesenchymal cell apoptotic process involved in metanephros development.	tmpzr1t_l9r_go_relaxed.owl	downregulation of mesenchymal cell apoptosis involved in metanephros development|inhibition of mesenchymal cell apoptosis involved in metanephros development|negative regulation of mesenchymal cell apoptosis involved in metanephros development|down regulation of mesenchymal cell apoptosis involved in metanephros development|down-regulation of mesenchymal cell apoptosis involved in metanephros development							yaf	2012-03-22T10:53:00Z					biological_process											owl:Class	
GO:0023024	biolink:NamedThing	MHC class I protein complex binding	Binding to a class I major histocompatibility complex.	tmpzr1t_l9r_go_relaxed.owl									2010-02-16T09:30:50Z					molecular_function											owl:Class	
GO:1902190	biolink:NamedThing	2-methylbutanoyl-CoA(4-) catabolic process	The chemical reactions and pathways resulting in the breakdown of 2-methylbutanoyl-CoA(4-).	tmpzr1t_l9r_go_relaxed.owl	2-methylbutanoyl-CoA(4-) degradation|2-methylbutanoyl-CoA(4-) breakdown|2-methylbutanoyl-CoA(4-) catabolism							ms	2013-06-06T09:40:20Z					biological_process											owl:Class	
GO:1902189	biolink:NamedThing	2-methylbutanoyl-CoA(4-) metabolic process	The chemical reactions and pathways involving 2-methylbutanoyl-CoA(4-).	tmpzr1t_l9r_go_relaxed.owl	2-methylbutanoyl-CoA(4-) metabolism							ms	2013-06-06T09:40:14Z					biological_process											owl:Class	
GO:0018389	biolink:NamedThing	N-terminal peptidyl-valine deamination	The deamination of the N-terminal valine residue of a protein to form isobutyrate.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0018058	biolink:NamedThing	N-terminal protein amino acid deamination, from amino carbon	The oxidative deamination of the alpha carbon of an encoded N-terminal amino acid, to form pyruvic acid retaining an amide bond between its 1-carboxyl group and the adjacent residue. The pyruvate 2-oxo group may become an enzyme active site, or it may be reduced to an alcohol.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0128|RESID:AA0129|RESID:AA0127									biological_process											owl:Class	
GO:0004679	biolink:NamedThing	AMP-activated protein kinase activity	Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein. This reaction requires the presence of AMP.	tmpzr1t_l9r_go_relaxed.owl	SNF1A/AMP-activated protein kinase activity|5'-AMP-activated protein kinase activity|AMPK activity				Reactome:R-HSA-6805470|Reactome:R-HSA-163691|Reactome:R-HSA-200423|Reactome:R-HSA-447074|Reactome:R-HSA-5673768|Reactome:R-HSA-1592244|EC:2.7.11.11|Reactome:R-HSA-380927									molecular_function											owl:Class	
GO:0045342	biolink:NamedThing	MHC class II biosynthetic process	The chemical reactions and pathways resulting in the formation of major histocompatibility protein class II.	tmpzr1t_l9r_go_relaxed.owl	major histocompatibility complex class II biosynthetic process|major histocompatibility complex class II biosynthesis|MHC class II biosynthesis|MHC class II formation|MHC class II synthesis|MHC class II anabolism													biological_process											owl:Class	
GO:0051565	biolink:NamedThing	negative regulation of smooth endoplasmic reticulum calcium ion concentration	Any process that decreases the concentration of calcium ions in the smooth endoplasmic reticulum.	tmpzr1t_l9r_go_relaxed.owl	smooth ER calcium ion concentration reduction|reduction of smooth ER calcium ion concentration|smooth endoplasmic reticulum calcium ion concentration reduction|reduction of smooth endoplasmic reticulum calcium ion concentration|reduction of calcium ion concentration in smooth endoplasmic reticulum|reduction of calcium ion concentration in smooth ER													biological_process											owl:Class	
GO:0032471	biolink:NamedThing	negative regulation of endoplasmic reticulum calcium ion concentration	Any process that decreases the concentration of calcium ions in the endoplasmic reticulum.	tmpzr1t_l9r_go_relaxed.owl	endoplasmic reticulum calcium ion concentration reduction|reduction of ER calcium ion concentration|reduction of calcium ion concentration in endoplasmic reticulum|reduction of calcium ion concentration in ER|ER calcium ion concentration reduction|reduction of endoplasmic reticulum calcium ion concentration													biological_process											owl:Class	
GO:0072201	biolink:NamedThing	negative regulation of mesenchymal cell proliferation	Any process that decreases the frequency, rate or extent of mesenchymal cell proliferation. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-03-01T03:43:29Z					biological_process											owl:Class	
GO:0097659	biolink:NamedThing	nucleic acid-templated transcription	The cellular synthesis of RNA on a template of nucleic acid (DNA or RNA).	tmpzr1t_l9r_go_relaxed.owl						Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.		pr	2014-10-01T13:49:27Z					biological_process											owl:Class	
GO:0047512	biolink:NamedThing	(S,S)-butanediol dehydrogenase activity	Catalysis of the reaction: (S,S)-butane-2,3-diol + NAD(+) = acetoin + H(+) + NADH.	tmpzr1t_l9r_go_relaxed.owl	L-butanediol dehydrogenase activity|(S,S)-butane-2,3-diol:NAD+ oxidoreductase activity|L-BDH|L(+)-2,3-butanediol dehydrogenase (L-acetoin forming)				EC:1.1.1.76|KEGG_REACTION:R03707|RHEA:12184|MetaCyc:SS-BUTANEDIOL-DEHYDROGENASE-RXN									molecular_function											owl:Class	
GO:0032923	biolink:NamedThing	organic phosphonate biosynthetic process	The chemical reactions and pathways resulting in the formation of phosphonates, any organic compound containing one or more C-PO(OH)2 or C-PO(OR)2 (with R=alkyl, aryl) groups. Synthesis of phosphonic acid itself, an inorganic compound without the biochemically relevant C-P bond, is not included.	tmpzr1t_l9r_go_relaxed.owl	organophosphonate biosynthetic process													biological_process											owl:Class	
GO:0070077	biolink:NamedThing	histone arginine demethylation	The modification of a histone by the removal of a methyl group from an arginine residue.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0051676	biolink:NamedThing	pullulan metabolic process	The chemical reactions and pathways involving pullulan, a neutral linear polysaccharide composed of repeating units of maltotriose joined by alpha-(1,6)-linkages.	tmpzr1t_l9r_go_relaxed.owl	pullulan metabolism													biological_process											owl:Class	
GO:0019776	biolink:NamedThing	Atg8 ligase activity	Catalysis of the covalent attachment of the ubiquitin-like protein Atg8 to substrate molecules; phosphatidylethanolamine is a known substrate.	tmpzr1t_l9r_go_relaxed.owl	APG8 conjugating enzyme activity|APG8 ligase activity|Atg8 conjugating enzyme activity				Reactome:R-HSA-5681981									molecular_function											owl:Class	
GO:0016606	biolink:NamedThing	LYSP100-associated nuclear domain	A nuclear body that is enriched in the lymphoid cell-specific protein LYSp100B; LANDs are globular, electron-dense structures and are morphologically distinct from the annular structures characteristic of PML bodies.	tmpzr1t_l9r_go_relaxed.owl	LANDs													cellular_component											owl:Class	
GO:1900421	biolink:NamedThing	positive regulation of cellular alcohol catabolic process	Any process that activates or increases the frequency, rate or extent of cellular alcohol catabolic process.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of cellular alcohol catabolic process|activation of cellular alcohol catabolic process|upregulation of cellular alcohol catabolic process|up regulation of cellular alcohol catabolic process							krc	2012-04-20T10:21:46Z					biological_process											owl:Class	
GO:1900419	biolink:NamedThing	regulation of cellular alcohol catabolic process	Any process that modulates the frequency, rate or extent of cellular alcohol catabolic process.	tmpzr1t_l9r_go_relaxed.owl								krc	2012-04-20T10:21:18Z					biological_process											owl:Class	
GO:1900364	biolink:NamedThing	negative regulation of mRNA polyadenylation	Any process that stops, prevents or reduces the frequency, rate or extent of mRNA polyadenylation.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of mRNA polyadenylylation|inhibition of cleavage and polyadenylylation specificity factor activity|downregulation of mRNA polyadenylylation|downregulation of cleavage and polyadenylylation specificity factor activity|down regulation of mRNA polyadenylylation|down-regulation of mRNA polyadenylation|down-regulation of mRNA polyadenylylation|inhibition of mRNA polyadenylation|downregulation of mRNA polyadenylation|down regulation of mRNA polyadenylation|inhibition of mRNA polyadenylylation|down-regulation of cleavage and polyadenylylation specificity factor activity|negative regulation of cleavage and polyadenylylation specificity factor activity|down regulation of cleavage and polyadenylylation specificity factor activity							pr	2012-04-12T04:36:31Z					biological_process											owl:Class	
GO:0035669	biolink:NamedThing	TRAM-dependent toll-like receptor 4 signaling pathway	Any series of molecular signals generated as a consequence of binding to a toll-like receptor 4 where the TRAM adaptor mediates transduction of the signal. Toll-like 4 receptors are pattern recognition receptors that bind bacterial lipopolysaccharide (LPS) to initiate an innate immune response.	tmpzr1t_l9r_go_relaxed.owl	TRAM-dependent toll-like receptor 4 signalling pathway|TRAM-dependent TLR4 signaling pathway							bf	2011-02-01T02:41:09Z					biological_process											owl:Class	
GO:0034142	biolink:NamedThing	toll-like receptor 4 signaling pathway	Any series of molecular signals generated as a consequence of binding to toll-like receptor 4.	tmpzr1t_l9r_go_relaxed.owl	TLR4 signaling pathway|toll-like receptor 4 signalling pathway													biological_process											owl:Class	
GO:0007035	biolink:NamedThing	vacuolar acidification	Any process that reduces the pH of the vacuole, measured by the concentration of the hydrogen ion.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0002119	biolink:NamedThing	nematode larval development	The process whose specific outcome is the progression of the nematode larva over time, from its formation to the mature structure. Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0060583	biolink:NamedThing	regulation of actin cortical patch localization	Any process that modulates the localization of an actin cortical patch. An actin cortical patch is a discrete actin-containing structure found just beneath the plasma membrane in fungal cells.	tmpzr1t_l9r_go_relaxed.owl	regulation of actin cortical patch localisation							dph	2009-05-08T01:58:42Z					biological_process											owl:Class	
GO:0071896	biolink:NamedThing	protein localization to adherens junction	Any process in which a protein is transported to, and/or maintained at the adherens junction.	tmpzr1t_l9r_go_relaxed.owl	protein localisation in cell-cell adherens junction|protein localization to cell-cell adherens junction|protein localisation in adherens junction|protein localisation to adherens junction|protein localisation to cell-cell adherens junction|protein localization in cell-cell adherens junction|protein localization in adherens junction							mah	2010-09-14T04:03:27Z			GO:1904696		biological_process											owl:Class	
GO:0045265	biolink:NamedThing	proton-transporting ATP synthase, stator stalk	One of two stalks that connect the catalytic core of the hydrogen-transporting ATP synthase to the membrane-associated Fo proteins; is thought to prevent futile rotation of the catalytic core.	tmpzr1t_l9r_go_relaxed.owl	hydrogen-transporting ATP synthase, stator stalk													cellular_component											owl:Class	
GO:1905318	biolink:NamedThing	meiosis I spindle assembly checkpoint signaling	Any spindle assembly checkpoint that is involved in meiosis I.	tmpzr1t_l9r_go_relaxed.owl	meiosis I spindle assembly checkpoint	https://github.com/geneontology/go-ontology/issues/20935						vw	2016-07-13T18:25:06Z					biological_process											owl:Class	
GO:0033316	biolink:NamedThing	meiotic spindle assembly checkpoint signaling	A signal transduction process that contributes to a meiotic spindle assembly checkpoint, that delays the metaphase/anaphase transition of a meiotic cell cycle until the spindle is correctly assembled and chromosomes are attached to the spindle.	tmpzr1t_l9r_go_relaxed.owl	meiotic spindle assembly checkpoint|signal transduction involved in meiotic spindle assembly checkpoint	https://github.com/geneontology/go-ontology/issues/20935										GO:0072465		biological_process											owl:Class	
GO:0050740	biolink:NamedThing	protein-FMN linkage via O3-riboflavin phosphoryl-L-threonine	The formation of a protein-FMN linkage via O3-riboflavin phosphoryl-L-threonine.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0349									biological_process											owl:Class	
GO:0140078	biolink:NamedThing	class I DNA-(apurinic or apyrimidinic site) endonuclease activity	Catalysis of the cleavage of an AP site 3' of the baseless site by a beta-lyase mechanism, leaving an unsaturated aldehyde, termed a 3'-(4-hydroxy-5-phospho-2-pentenal) residue, and a 5'-phosphate.	tmpzr1t_l9r_go_relaxed.owl	AP endonuclease class I activity|AP site-DNA 5'-phosphomonoester-lyase activity|class I DNA-(apurinic or apyrimidinic site) lyase activity|DNA-(apurinic or apyrimidinic site) lyase activity|DNA-(apurinic or apyrimidinic site) 5'-phosphomonoester-lyase activity	https://github.com/geneontology/go-ontology/issues/22262			RHEA:66592|Wikipedia:AP_endonuclease|MetaCyc:4.2.99.18-RXN|EC:4.2.99.18	Note that this term is does not have parentage in the 'nuclease activity' branch of the ontology because both GO and the Enzyme Commission define nuclease activity as a type of hydrolysis. Class II AP endonuclease is a nuclease, but not Class I, III and IV.		pg	2017-07-24T11:33:34Z					molecular_function											owl:Class	
GO:0003906	biolink:NamedThing	DNA-(apurinic or apyrimidinic site) endonuclease activity	Catalysis of the cleavage of the C-O-P bond in the AP site created when DNA glycosylase removes a damaged base, involved in the DNA base excision repair pathway (BER).	tmpzr1t_l9r_go_relaxed.owl	UV endonuclease|abasic deoxyendoribonuclease activity|apyrimidinic deoxyendoribonuclease activity|apurinic/apyrimidinic endodeoxyribonuclease activity|deoxyribonuclease (apurinic or apyrimidinic) activity|AP deoxyendoribonuclease activity|endonuclease VIII activity|apurinic deoxyendoribonuclease activity	https://github.com/geneontology/go-ontology/issues/15308|https://github.com/geneontology/go-ontology/issues/22262|https://github.com/geneontology/go-ontology/issues/15357			Reactome:R-HSA-5649725|Reactome:R-HSA-110375|Reactome:R-HSA-5649711	Note that this term is does not have parentage in the 'nuclease activity' branch of the ontology because both GO and the Enzyme Commission define nuclease activity as a type of hydrolysis. Class II AP endonuclease is a nuclease, but not Class I, III and IV.								molecular_function											owl:Class	
GO:0035727	biolink:NamedThing	lysophosphatidic acid binding	Binding to lysophosphatidic acid (LPA), a phospholipid derivative that acts as a potent mitogen due to its activation of high-affinity G protein-coupled receptors.	tmpzr1t_l9r_go_relaxed.owl	LPA binding							bf	2011-03-10T03:00:05Z					molecular_function											owl:Class	
GO:0009072	biolink:NamedThing	aromatic amino acid family metabolic process	The chemical reactions and pathways involving aromatic amino acid family, amino acids with aromatic ring (phenylalanine, tyrosine, tryptophan).	tmpzr1t_l9r_go_relaxed.owl	aromatic amino acid family metabolism													biological_process											owl:Class	
GO:0003827	biolink:NamedThing	alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity	Catalysis of the reaction: 3-(alpha-D-mannosyl)-beta-D-mannosyl-R + UDP-N-acetyl-alpha-D-glucosamine = 3-(2-[N-acetyl-beta-D-glucosaminyl]-alpha-D-mannosyl)-beta-D-mannosyl-R + H(+) + UDP.	tmpzr1t_l9r_go_relaxed.owl	GnTI|UDP-N-acetyl-D-glucosamine:3-(alpha-D-mannosyl)-beta-D-mannosyl-glycoprotein 2-beta-N-acetyl-D-glucosaminyltransferase activity|UDP-N-acetylglucosaminyl:alpha-1,3-D-mannoside-beta-1,2-N-acetylglucosaminyltransferase I activity|alpha-1,3-mannosyl-glycoprotein beta-1,2-N-acetylglucosaminyltransferase activity|alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase activity|GNTI activity|alpha-1,3-mannosylglycoprotein beta-1,2-N-acetylglucosaminyltransferase activity|N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase I activity|UDP-N-acetylglucosaminyl:alpha-3-D-mannoside beta-1,2-N-acetylglucosaminyltransferase I activity|uridine diphosphoacetylglucosamine-alpha-1,3-mannosylglycoprotein beta-1,2-N-acetylglucosaminyltransferase activity|N-acetylglucosaminyltransferase I activity				KEGG_REACTION:R05983|Reactome:R-HSA-964768|MetaCyc:2.4.1.101-RXN|RHEA:11456|EC:2.4.1.101									molecular_function											owl:Class	
GO:0019876	biolink:NamedThing	nylon catabolic process	The chemical reactions and pathways resulting in the breakdown of nylon, a polymer where the main polymer chain comprises recurring amide groups; these compounds are generally formed from combinations of diamines, diacids and amino acids.	tmpzr1t_l9r_go_relaxed.owl	nylon breakdown|nylon degradation|nylon catabolism													biological_process											owl:Class	
GO:0061559	biolink:NamedThing	cranial ganglion morphogenesis	The process in which the anatomical structure of a cranial ganglion is generated and organized.	tmpzr1t_l9r_go_relaxed.owl	cranial ganglia morphogenesis							dph	2013-07-10T09:02:15Z					biological_process											owl:Class	
GO:0030414	biolink:NamedThing	peptidase inhibitor activity	Binds to and stops, prevents or reduces the activity of a peptidase, any enzyme that catalyzes the hydrolysis peptide bonds.	tmpzr1t_l9r_go_relaxed.owl	protease inhibitor activity													molecular_function											owl:Class	
GO:0047490	biolink:NamedThing	pectin lyase activity	Catalysis of the reaction: a pectin = an oligosaccharide with 4-deoxy-6-O-methyl-alpha-D-galact-4-enuronate end + a pectin. This reaction is the eliminative cleavage of (1->4)-alpha-D-galacturonan methyl ester to give oligosaccharides with 4-deoxy-6-O-methyl-alpha-D-galact-4-enuronosyl groups at their nonreducing ends.	tmpzr1t_l9r_go_relaxed.owl	endo-pectin lyase activity|polymethylgalacturonic transeliminase activity|pectin trans-eliminase activity|pectolyase activity|PNL activity|PMGL activity|(1->4)-6-O-methyl-alpha-D-galacturonan lyase activity|PL activity|pectin methyltranseliminase activity				EC:4.2.2.10|MetaCyc:4.2.2.10-RXN									molecular_function											owl:Class	
GO:0030253	biolink:NamedThing	protein secretion by the type I secretion system	The process in which proteins are secreted into the extracellular milieu via the type I secretion system; secretion occurs in a continuous process without the distinct presence of periplasmic intermediates and does not involve proteolytic processing of secreted proteins.	tmpzr1t_l9r_go_relaxed.owl	type I protein secretion system|protein secretion by the TOSS|protein secretion by the type I protein secretion system					Note that this term represents an activity and not a cellular structure. Consider also annotating to the cellular component term 'type I protein secretion system complex ; GO:0030256'.								biological_process											owl:Class	
GO:1901858	biolink:NamedThing	regulation of mitochondrial DNA metabolic process	Any process that modulates the frequency, rate or extent of mitochondrial DNA metabolic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of mtDNA metabolic process|regulation of mitochondrial DNA metabolism|regulation of mtDNA metabolism							yaf	2013-02-01T10:05:04Z					biological_process											owl:Class	
GO:0051087	biolink:NamedThing	chaperone binding	Binding to a chaperone protein, a class of proteins that bind to nascent or unfolded polypeptides and ensure correct folding or transport.	tmpzr1t_l9r_go_relaxed.owl	co-chaperone activity|chaperone protein binding|co-chaperonin activity													molecular_function											owl:Class	
GO:2000563	biolink:NamedThing	positive regulation of CD4-positive, alpha-beta T cell proliferation	Any process that activates or increases the frequency, rate or extent of CD4-positive, alpha-beta T cell proliferation.	tmpzr1t_l9r_go_relaxed.owl								ebc	2011-04-03T09:01:15Z					biological_process											owl:Class	
GO:2000516	biolink:NamedThing	positive regulation of CD4-positive, alpha-beta T cell activation	Any process that activates or increases the frequency, rate or extent of CD4-positive, alpha-beta T cell activation.	tmpzr1t_l9r_go_relaxed.owl								ebc	2011-03-22T10:37:06Z					biological_process											owl:Class	
GO:0033591	biolink:NamedThing	response to L-ascorbic acid	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an L-ascorbic acid (vitamin C) stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to ascorbic acid|response to vitamin C|response to L-ascorbate													biological_process											owl:Class	
GO:0004446	biolink:NamedThing	inositol-hexakisphosphate phosphatase activity	Catalysis of the reaction: myo-inositol hexakisphosphate + H2O = myo-inositol pentakisphosphate (mixed isomers) + phosphate.	tmpzr1t_l9r_go_relaxed.owl	multiple inositol-polyphosphate phosphatase activity|1D-myo-inositol-hexakisphosphate 5-phosphohydrolase activity|inositol tetrakisphosphate phosphomonoesterase activity|MIPP activity				MetaCyc:RXN-7920|EC:3.1.3.62									molecular_function											owl:Class	
GO:0140145	biolink:NamedThing	copper ion export from vacuole	The directed movement of copper ions out of the vacuole across the vacuolar membrane.	tmpzr1t_l9r_go_relaxed.owl								pg	2017-12-13T15:02:39Z					biological_process											owl:Class	
GO:0060003	biolink:NamedThing	copper ion export	The directed movement of copper ions out of a cell or organelle.	tmpzr1t_l9r_go_relaxed.owl	copper export													biological_process											owl:Class	
GO:0060270	biolink:NamedThing	main body follicle cell migration	The ovarian follicle cell migration process in which follicle cells migrate posteriorly to form a columnar epithelium over the oocyte.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0051757	biolink:NamedThing	meiotic sister chromatid separation	The process in which sister chromatids are physically detached from each other during meiosis.	tmpzr1t_l9r_go_relaxed.owl	meiotic sister chromatid resolution													biological_process											owl:Class	
GO:1901436	biolink:NamedThing	positive regulation of toluene catabolic process	Any process that activates or increases the frequency, rate or extent of toluene catabolic process.	tmpzr1t_l9r_go_relaxed.owl	upregulation of toluene breakdown|upregulation of toluene catabolic process|activation of toluene catabolism|positive regulation of toluene catabolism|up regulation of toluene breakdown|up regulation of toluene catabolism|upregulation of toluene catabolism|activation of toluene breakdown|up-regulation of toluene breakdown|up-regulation of toluene catabolic process|positive regulation of toluene breakdown|up-regulation of toluene degradation|activation of toluene degradation|up regulation of toluene degradation|up-regulation of toluene catabolism|activation of toluene catabolic process|upregulation of toluene degradation|up regulation of toluene catabolic process|positive regulation of toluene degradation							tt	2012-10-01T21:13:57Z					biological_process											owl:Class	
GO:0007576	biolink:NamedThing	nucleolar fragmentation	The cell aging process that results in the nucleolus breaking down into fragments.	tmpzr1t_l9r_go_relaxed.owl	nucleolar size increase											GO:0046616		biological_process											owl:Class	
GO:0007000	biolink:NamedThing	nucleolus organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nucleolus.	tmpzr1t_l9r_go_relaxed.owl	nucleolus organization and biogenesis|nucleolus organisation													biological_process											owl:Class	
GO:0071682	biolink:NamedThing	endocytic vesicle lumen	The volume enclosed by the membrane of an endocytic vesicle.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-02-18T04:21:53Z					cellular_component											owl:Class	
GO:0045742	biolink:NamedThing	positive regulation of epidermal growth factor receptor signaling pathway	Any process that activates or increases the frequency, rate or extent of epidermal growth factor receptor signaling pathway activity.	tmpzr1t_l9r_go_relaxed.owl	upregulation of epidermal growth factor receptor signaling pathway|positive regulation of EGF receptor signaling pathway|positive regulation of EGF receptor signalling pathway|up regulation of epidermal growth factor receptor signaling pathway|activation of epidermal growth factor receptor signaling pathway|up-regulation of epidermal growth factor receptor signaling pathway|stimulation of epidermal growth factor receptor signaling pathway|positive regulation of EGFR signaling pathway													biological_process											owl:Class	
GO:1990471	biolink:NamedThing	piRNA uni-strand cluster binding	Binding to uni-strand piRNA clusters, double-stranded DNA regions that give rise to PIWI-interacting RNAs (piRNAs) that map predominantly to only one strand and exhibit hallmarks of canonical Pol II transcription. Uni-strand piRNA clusters are found in many taxa.	tmpzr1t_l9r_go_relaxed.owl								bhm	2014-08-29T14:37:35Z					molecular_function											owl:Class	
GO:0042986	biolink:NamedThing	positive regulation of amyloid precursor protein biosynthetic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of amyloid precursor protein (APP), the precursor of amyloid-beta.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of APP biosynthetic process|stimulation of amyloid precursor protein biosynthetic process|positive regulation of APP biosynthesis|up regulation of amyloid precursor protein biosynthetic process|positive regulation of amyloid precursor protein anabolism|positive regulation of amyloid precursor protein synthesis|activation of amyloid precursor protein biosynthetic process|positive regulation of amyloid precursor protein formation|up-regulation of amyloid precursor protein biosynthetic process|positive regulation of amyloid precursor protein biosynthesis|upregulation of amyloid precursor protein biosynthetic process													biological_process											owl:Class	
GO:0001183	biolink:NamedThing	transcription elongation from RNA polymerase I promoter for nuclear large rRNA transcript	The extension of an RNA molecule after transcription initiation and promoter clearance at an RNA polymerase I promoter for the nuclear large ribosomal RNA (rRNA) transcript by the addition of ribonucleotides catalyzed by RNA polymerase I.	tmpzr1t_l9r_go_relaxed.owl								krc	2011-08-15T03:57:25Z					biological_process											owl:Class	
GO:1901800	biolink:NamedThing	positive regulation of proteasomal protein catabolic process	Any process that activates or increases the frequency, rate or extent of proteasomal protein catabolic process.	tmpzr1t_l9r_go_relaxed.owl	activation of proteasomal protein catabolic process|upregulation of proteasomal protein catabolic process|up regulation of proteasome-mediated protein catabolic process|up-regulation of proteasomal protein catabolic process|positive regulation of proteasome-mediated protein catabolic process|positive regulation of proteasome-mediated protein catabolism|up regulation of proteasomal protein catabolic process|upregulation of proteasome-mediated protein catabolism|up-regulation of proteasome-mediated protein catabolic process|up regulation of proteasome-mediated protein catabolism|activation of proteasome-mediated protein catabolism|upregulation of proteasome-mediated protein catabolic process|activation of proteasome-mediated protein catabolic process|up-regulation of proteasome-mediated protein catabolism							rl	2013-01-21T20:10:58Z					biological_process											owl:Class	
GO:0048695	biolink:NamedThing	negative regulation of collateral sprouting of injured axon	Any process that stops, prevents, or reduces the frequency, rate or extent of collateral sprouting of an injured axon.	tmpzr1t_l9r_go_relaxed.owl	inhibition of collateral sprouting of injured axon|downregulation of collateral sprouting of injured axon|down-regulation of collateral sprouting of injured axon|down regulation of collateral sprouting of injured axon													biological_process											owl:Class	
GO:0050957	biolink:NamedThing	equilibrioception	The series of events required for an organism to receive an orientational stimulus, convert it to a molecular signal, and recognize and characterize the signal. Equilibrioception refers to a combination of processes by which an organism can perceive its orientation with respect to gravity. In animals, stimuli come from labyrinth system of the inner ears, monitoring the direction of motion; visual stimuli, with information on orientation and motion; pressure receptors, which tell the organism which body surfaces are in contact with the ground; and proprioceptive cues, which report which parts of the body are in motion.	tmpzr1t_l9r_go_relaxed.owl	sensory perception of orientation with respect to gravity				Wikipedia:Equilibrioception									biological_process											owl:Class	
GO:0097587	biolink:NamedThing	MutLgamma complex	A heterodimer involved in the recognition of base-base and small insertion/deletion mismatches. In S. cerevisiae the complex consists of two subunits, Mlh1 and Mlh3.	tmpzr1t_l9r_go_relaxed.owl								pr	2014-03-06T11:48:12Z					cellular_component											owl:Class	
GO:0080011	biolink:NamedThing	baruol synthase activity	Catalysis of the reaction: (S)-2,3-epoxysqualene = baruol. Baruol is also known as D:B-Friedo-Baccharan-5,21-dien-3-ol.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-9685|RHEA:31987|EC:5.4.99.57									molecular_function											owl:Class	
GO:0097339	biolink:NamedThing	glycolate transmembrane transport	The process in which glycolate is transported across a membrane. Glycolate is the anion of hydroxyethanoic acid (glycolic acid).	tmpzr1t_l9r_go_relaxed.owl	glycolate membrane transport					Note that this term is not intended for use in annotating lateral movement within membranes.		pr	2012-06-12T05:12:35Z					biological_process											owl:Class	
GO:1900866	biolink:NamedThing	glycolate transport	The directed movement of a glycolate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl								pr	2012-06-12T04:29:56Z					biological_process											owl:Class	
GO:1900701	biolink:NamedThing	regulation of orcinol biosynthetic process	Any process that modulates the frequency, rate or extent of orcinol biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of orcinol anabolism|regulation of orcinol biosynthesis|regulation of orcinol synthesis|regulation of orcinol formation							di	2012-05-22T04:57:59Z					biological_process											owl:Class	
GO:0003435	biolink:NamedThing	smoothened signaling pathway involved in growth plate cartilage chondrocyte development	The series of molecular signals generated as a consequence of activation of the transmembrane protein Smoothened that contributes to the progression of a growth plate cartilage chondrocyte over time.	tmpzr1t_l9r_go_relaxed.owl	hedgehog signaling pathway involved in growth plate cartilage chondrocyte development|hh signaling pathway involved in growth plate cartilage chondrocyte development|smoothened signalling pathway involved in growth plate cartilage chondrocyte development							dph	2009-12-22T01:02:42Z					biological_process											owl:Class	
GO:2000710	biolink:NamedThing	negative regulation of maintenance of meiotic sister chromatid cohesion, centromeric	Any process that stops, prevents or reduces the frequency, rate or extent of maintenance of meiotic sister chromatid cohesion in the centromeric region.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of maintenance of meiotic sister chromatin cohesion at centromere|negative regulation of maintenance of centromeric meiotic sister chromatin cohesion|negative regulation of maintenance of sister chromatin cohesion at centromere at meiosis I							mah	2011-06-01T12:41:16Z					biological_process											owl:Class	
GO:0043502	biolink:NamedThing	regulation of muscle adaptation	Any process that modulates the frequency, rate or extent of muscle adaptation.	tmpzr1t_l9r_go_relaxed.owl	regulation of muscle plasticity													biological_process											owl:Class	
GO:0070518	biolink:NamedThing	alpha4-beta1 integrin-CD53 complex	A protein complex that consists of an alpha4-beta1 integrin complex bound to membrane protein CD53, a member of the tetraspan family.	tmpzr1t_l9r_go_relaxed.owl	ITGA4-ITGB1-CD53 complex													cellular_component											owl:Class	
GO:0015942	biolink:NamedThing	formate metabolic process	The chemical reactions and pathways involving formate, also known as methanoate, the anion HCOO- derived from methanoic (formic) acid.	tmpzr1t_l9r_go_relaxed.owl	formate metabolism													biological_process											owl:Class	
GO:0033185	biolink:NamedThing	dolichol-phosphate-mannose synthase complex	A protein complex that possesses dolichyl-phosphate beta-D-mannosyltransferase activity; contains a catalytic subunit, a regulatory subunit, and a third subunit that stabilizes the complex. In human and several other metazoa, the subunits are named DPM1, DPM2 and DPM3, respectively.	tmpzr1t_l9r_go_relaxed.owl	DPM synthase complex|dolichyl-phosphate beta-D-mannosyltransferase complex													cellular_component											owl:Class	
GO:0031501	biolink:NamedThing	mannosyltransferase complex	A complex that posseses mannosyltransferase activity.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0002529	biolink:NamedThing	regulation of plasma kallikrein-kinin cascade	Any process that modulates the frequency, rate, or extent of the plasma kallikrein-kinin cascade.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0003858	biolink:NamedThing	3-hydroxybutyrate dehydrogenase activity	Catalysis of the reaction: (R)-3-hydroxybutanoate + NAD(+) = acetoacetate + H(+) + NADH.	tmpzr1t_l9r_go_relaxed.owl	D-beta-hydroxybutyrate dehydrogenase activity				EC:1.1.1.30|Reactome:R-HSA-73912|MetaCyc:3-HYDROXYBUTYRATE-DEHYDROGENASE-RXN|KEGG_REACTION:R01361|Reactome:R-HSA-73920|Reactome:R-HSA-5696457|RHEA:20521									molecular_function											owl:Class	
GO:2000659	biolink:NamedThing	regulation of interleukin-1-mediated signaling pathway	Any process that modulates the frequency, rate or extent of interleukin-1-mediated signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	regulation of interleukin-1-mediated signalling pathway|regulation of interleukin-1 beta-mediated signaling pathway|regulation of IL-1-mediated signaling pathway|regulation of interleukin-1 alpha-mediated signaling pathway|regulation of IL-1 alpha-mediated signaling pathway|regulation of IL-1 beta-mediated signaling pathway							dph	2011-05-03T07:13:31Z					biological_process											owl:Class	
GO:0021622	biolink:NamedThing	oculomotor nerve morphogenesis	The process in which the anatomical structure of the oculomotor nerve is generated and organized. This motor nerve innervates all extraocular muscles except the superior oblique and the lateral rectus muscles. The superior division supplies the levator palpebrae superioris and superior rectus muscles. The inferior division supplies the medial rectus, inferior rectus and inferior oblique muscles. This nerve also innervates the striated muscles of the eyelid. Pupillary constriction and lens movement are mediated by this nerve for near vision. In the orbit the inferior division sends branches that enter the ciliary ganglion where they form functional contacts (synapses) with the ganglion cells. The ganglion cells send nerve fibers into the back of the eye where they travel to ultimately innervate the ciliary muscle and the constrictor pupillae muscle.	tmpzr1t_l9r_go_relaxed.owl	CN III morphogenesis													biological_process											owl:Class	
GO:0060505	biolink:NamedThing	epithelial cell proliferation involved in lung bud dilation	The multiplication or reproduction of epithelial cells that contribute to the radial growth of a lung bud.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0034756	biolink:NamedThing	regulation of iron ion transport	Any process that modulates the frequency, rate or extent of the directed movement of iron ions (Fe) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	regulation of iron ion import|regulation of iron transport|regulation of iron import|regulation of Fe transport							mah	2012-04-18T04:00:14Z			GO:1900390		biological_process											owl:Class	
GO:0000380	biolink:NamedThing	alternative mRNA splicing, via spliceosome	The process of generating multiple mRNA molecules from a given set of exons by differential use of exons from the primary transcript(s) to form multiple mature mRNAs that vary in their exon composition.	tmpzr1t_l9r_go_relaxed.owl	splice site selection|alternative nuclear mRNA splicing, via spliceosome					Note that this process most commonly occurs in cis, selecting or skipping exons from the same primary transcript, but it has also been observed to occur in trans at low frequency, at least in some mammals.								biological_process											owl:Class	
GO:0000398	biolink:NamedThing	mRNA splicing, via spliceosome	The joining together of exons from one or more primary transcripts of messenger RNA (mRNA) and the excision of intron sequences, via a spliceosomal mechanism, so that mRNA consisting only of the joined exons is produced.	tmpzr1t_l9r_go_relaxed.owl	mRNA splicing|splicing GT-AG intron|splicing AT-AC intron|nuclear mRNA splicing, via spliceosome|nuclear mRNA splicing via U2-type spliceosome|nuclear mRNA splicing via U12-type spliceosome|pre-mRNA splicing					Note that although the many U12-type introns have the sequence AT-AC at the intron termini, some introns with these terminal sequences are spliced by the U2-type spliceosome. The distinguishing characteristics are sequences near the 5' splice site and the branch point sequences of the intron. Note that although the majority of U2-type introns have the sequence GU-AG at the intron termini, some introns with these terminal sequences are spliced by the U12-type spliceosome. The distinguishing characteristics are sequences near the 5' splice site and the branch point sequences of the intron.						GO:0006375|GO:0006374		biological_process											owl:Class	
GO:1903657	biolink:NamedThing	negative regulation of type IV pilus biogenesis	Any process that stops, prevents or reduces the frequency, rate or extent of type IV pilus biogenesis.	tmpzr1t_l9r_go_relaxed.owl	downregulation of type IV fimbria assembly|inhibition of TFP biogenesis|downregulation of type IV fimbrium assembly|negative regulation of TFP biogenesis|down regulation of type IV fimbrial assembly|downregulation of TFP biogenesis|negative regulation of type IV fimbria biogenesis|inhibition of type IV pilus biosynthesis|inhibition of type IV fimbrial biogenesis|inhibition of type IV fimbria biogenesis|down-regulation of type IV fimbriae biogenesis|negative regulation of type IV fimbrium assembly|negative regulation of type IV fimbria assembly|down-regulation of type IV fimbria biogenesis|negative regulation of type IV fimbrium biogenesis|down regulation of type IV fimbriae biogenesis|down-regulation of type IV fimbrium biogenesis|downregulation of type IV pilus biosynthesis|negative regulation of type IV fimbrial assembly|negative regulation of type IV fimbriae assembly|down-regulation of type IV pilus biogenesis|negative regulation of type IV pilus biosynthesis|downregulation of type IV fimbria biogenesis|inhibition of type IV fimbria assembly|inhibition of type IV pilus biogenesis|down regulation of type IV pilus biosynthesis|down-regulation of TFP biogenesis|down regulation of TFP biogenesis|down regulation of type IV fimbrial biogenesis|down regulation of type IV fimbrium assembly|downregulation of type IV fimbrial assembly|down-regulation of type IV fimbrial biogenesis|down regulation of type IV fimbriae assembly|inhibition of type 4 pilus biogenesis|downregulation of type IV fimbriae biogenesis|down regulation of type IV fimbria assembly|negative regulation of type IV fimbriae biogenesis|down-regulation of type IV fimbrial assembly|down regulation of type 4 pilus biogenesis|downregulation of type IV fimbrial biogenesis|downregulation of type IV pilus biogenesis|down regulation of type IV fimbria biogenesis|inhibition of type IV fimbrial assembly|downregulation of type IV fimbrium biogenesis|inhibition of type IV fimbriae assembly|down-regulation of type IV fimbrium assembly|downregulation of type 4 pilus biogenesis|negative regulation of type IV fimbrial biogenesis|inhibition of type IV fimbriae biogenesis|down-regulation of type IV pilus biosynthesis|inhibition of type IV fimbrium assembly|down-regulation of type IV fimbriae assembly|negative regulation of type 4 pilus biogenesis|inhibition of type IV fimbrium biogenesis|down-regulation of type IV fimbria assembly|down regulation of type IV fimbrium biogenesis|down regulation of type IV pilus biogenesis|downregulation of type IV fimbriae assembly|down-regulation of type 4 pilus biogenesis							jl	2014-11-25T12:03:24Z					biological_process											owl:Class	
GO:2001306	biolink:NamedThing	lipoxin B4 biosynthetic process	The chemical reactions and pathways resulting in the formation of lipoxin B4. Lipoxin B4 is a C20 hydroxy fatty acid having (5S)-, (14R)- and (15S)-hydroxy groups as well as (6E)- (8Z)-, (10E)- and (12E)-double bonds.	tmpzr1t_l9r_go_relaxed.owl	lipoxin B4 biosynthesis|LXB4 formation|LXB4 biosynthesis|lipoxin B4 synthesis|lipoxin B4 anabolism|LXB4 anabolism|LXB4 synthesis|LXB4 biosynthetic process|lipoxin B4 formation							bf	2012-03-07T11:15:04Z					biological_process											owl:Class	
GO:0016411	biolink:NamedThing	acylglycerol O-acyltransferase activity	Catalysis of the transfer of an acyl group to an oxygen atom on the acylglycerol molecule.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-1482647|Reactome:R-HSA-1482654									molecular_function											owl:Class	
GO:1904279	biolink:NamedThing	regulation of transcription by RNA polymerase V	Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase V.	tmpzr1t_l9r_go_relaxed.owl	regulation of transcription from RNA polymerase V promoter|regulation of transcription from RNA pol V promoter							tb	2015-06-03T22:01:47Z					biological_process											owl:Class	
GO:0090428	biolink:NamedThing	perianth development	The process whose specific outcome is the progression of the perianth over time, from its formation to the mature structure. The perianth is a collective phyllome structure composed of two or more petals, sepals, or tepals.	tmpzr1t_l9r_go_relaxed.owl								tb	2012-05-08T06:02:15Z					biological_process											owl:Class	
GO:0007321	biolink:NamedThing	sperm displacement	The physical displacement of sperm stored from previous mating encounters.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0070714	biolink:NamedThing	RNA guanosine-uridine insertion	The modification of an RNA molecule by insertion of an guanosine-uridine insertion dinucleotide.	tmpzr1t_l9r_go_relaxed.owl	RNA GU insertion							mah	2009-06-08T05:33:20Z					biological_process											owl:Class	
GO:0070707	biolink:NamedThing	RNA dinucleotide insertion	The modification of an RNA molecule by insertion of a dinucleotide.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-06-08T04:50:59Z					biological_process											owl:Class	
GO:0003273	biolink:NamedThing	cell migration involved in endocardial cushion formation	The orderly movement of a cell from one site to another that will contribute to the formation of an endocardial cushion. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-10-20T09:08:44Z					biological_process											owl:Class	
GO:0045831	biolink:NamedThing	negative regulation of light-activated channel activity	Any process that stops, prevents, or reduces the frequency, rate or extent of light-activated channel activity.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of light-activated channel activity|downregulation of light-activated channel activity|down regulation of light-activated channel activity|inhibition of light-activated channel activity													biological_process											owl:Class	
GO:1901167	biolink:NamedThing	3-chlorocatechol metabolic process	The chemical reactions and pathways involving 3-chlorocatechol.	tmpzr1t_l9r_go_relaxed.owl	3-chlorocatechol metabolism							yaf	2012-07-19T09:33:16Z					biological_process											owl:Class	
GO:0048526	biolink:NamedThing	imaginal disc-derived wing expansion	The process of expanding or inflating the folded imaginal disc-derived pupal wing, and the adhering of the dorsal and ventral surfaces, to form the mature adult wing.	tmpzr1t_l9r_go_relaxed.owl	wing inflation|wing expansion													biological_process											owl:Class	
GO:0048359	biolink:NamedThing	mucilage metabolic process involved in seed coat development	The chemical reactions and pathways involving mucilage that occur as part of seed coat development; mucilage is normally synthesized during seed coat development.	tmpzr1t_l9r_go_relaxed.owl	mucilage metabolic process during seed coat development|mucilage metabolism during seed coat development													biological_process											owl:Class	
GO:0150175	biolink:NamedThing	regulation of phosphatidylethanolamine metabolic process	Any process that modulates the frequency, rate or extent of phosphatidylethanolamine metabolic process.	tmpzr1t_l9r_go_relaxed.owl								bc	2020-01-21T14:04:12Z					biological_process											owl:Class	
GO:1900726	biolink:NamedThing	osmoregulated periplasmic glucan catabolic process	The chemical reactions and pathways resulting in the breakdown of osmoregulated periplasmic glucan.	tmpzr1t_l9r_go_relaxed.owl	osmoregulated periplasmic glucan degradation|osmoregulated periplasmic glucan breakdown|osmoregulated periplasmic glucan catabolism							jl	2012-05-24T03:18:54Z					biological_process											owl:Class	
GO:0005130	biolink:NamedThing	granulocyte colony-stimulating factor receptor binding	Binding to a granulocyte colony-stimulating factor receptor.	tmpzr1t_l9r_go_relaxed.owl	granulocyte colony stimulating factor receptor binding|GC-SF receptor ligand|granulocyte colony-stimulating factor|granulocyte colony-stimulating factor receptor ligand|G-CSF receptor ligand													molecular_function											owl:Class	
GO:0035119	biolink:NamedThing	embryonic pelvic fin morphogenesis	The process, occurring in the embryo, by which the anatomical structures of the pelvic fin are generated and organized. The pelvic fins are bilaterally paired fins mounted in a ventral-lateral position on most fish. These fins are used primarily for lateral mobility and propulsion.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0035139	biolink:NamedThing	pelvic fin morphogenesis	The process in which the anatomical structures of the pelvic fin are generated and organized. Pelvic fins are bilaterally paired fins mounted in a ventral-lateral position on most fish. These fins are used primarily for lateral mobility and propulsion.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0070495	biolink:NamedThing	negative regulation of thrombin-activated receptor signaling pathway	Any process that stops, prevents, or reduces the frequency, rate or extent of thrombin-activated receptor protein signaling pathway activity. A thrombin receptor signaling pathway is the series of molecular signals generated as a consequence of a thrombin-activated receptor binding to one of its physiological ligands.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of thrombin receptor signaling pathway|negative regulation of thrombin receptor signalling pathway													biological_process											owl:Class	
GO:1905311	biolink:NamedThing	negative regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis	Any process that stops, prevents or reduces the frequency, rate or extent of cardiac neural crest cell migration involved in outflow tract morphogenesis.	tmpzr1t_l9r_go_relaxed.owl	inhibition of cardiac neural crest cell migration involved in outflow tract morphogenesis|down regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis|down-regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis|downregulation of cardiac neural crest cell migration involved in outflow tract morphogenesis							rl	2016-07-11T17:34:35Z					biological_process											owl:Class	
GO:0034849	biolink:NamedThing	2-naphthoate CoA-transferase activity	Catalysis of the reaction: 2-naphthoyl-CoA + OH- = 2-naphthoate + CoASH.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r1262									molecular_function											owl:Class	
GO:0046020	biolink:NamedThing	negative regulation of transcription from RNA polymerase II promoter by pheromones	Any process involving pheromones that stops, prevents or reduces the rate of transcription from an RNA polymerase II promoter.	tmpzr1t_l9r_go_relaxed.owl	downregulation of transcription from RNA polymerase II promoter by pheromones|negative regulation of transcription from Pol II promoter by pheromones|down-regulation of transcription from RNA polymerase II promoter by pheromones|inhibition of transcription from RNA polymerase II promoter by pheromones|down regulation of transcription from RNA polymerase II promoter by pheromones													biological_process											owl:Class	
GO:1901344	biolink:NamedThing	response to leptomycin B	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leptomycin B stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2012-09-07T13:20:47Z					biological_process											owl:Class	
GO:0001208	biolink:NamedThing	histone H2A-H2B dimer displacement	The removal of a H2A-H2B histone dimer from a nucleosome within chromatin.	tmpzr1t_l9r_go_relaxed.owl								krc	2012-03-27T11:03:40Z					biological_process											owl:Class	
GO:0001207	biolink:NamedThing	histone displacement	The removal of histones, including histone dimers, from nucleosomes within chromatin.	tmpzr1t_l9r_go_relaxed.owl								krc	2012-03-27T10:56:56Z					biological_process											owl:Class	
GO:0099001	biolink:NamedThing	viral genome ejection through host cell envelope, long flexible tail mechanism	Ejection by a non-enveloped prokaryotic virus of its genome into the host cytoplasm via a long, flexible tail ejection system consisting a baseplate, a central tube and a terminator complex which attaches the tail to the phage capsid.  Upon binding to the host cell surface, the baseplate changes its conformation and triggers genome ejection into the host cell cytoplasm.	tmpzr1t_l9r_go_relaxed.owl	viral long flexible tail ejection system				VZ:3952									biological_process											owl:Class	
GO:1902527	biolink:NamedThing	positive regulation of protein monoubiquitination	Any process that activates or increases the frequency, rate or extent of protein monoubiquitination.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of protein monoubiquitinylation|up regulation of protein monoubiquitination|up regulation of protein monoubiquitinylation|activation of protein monoubiquitination|up-regulation of protein monoubiquitylation|upregulation of protein monoubiquitination|positive regulation of protein monoubiquitinylation|upregulation of protein monoubiquitinylation|activation of protein monoubiquitylation|positive regulation of protein monoubiquitylation|up-regulation of protein monoubiquitination|up regulation of protein monoubiquitylation|upregulation of protein monoubiquitylation|activation of protein monoubiquitinylation					An example is BIRC2 (UniProt ID Q13490) in PMID:21931591.		ppm	2013-12-02T09:59:21Z					biological_process											owl:Class	
GO:1902525	biolink:NamedThing	regulation of protein monoubiquitination	Any process that modulates the frequency, rate or extent of protein monoubiquitination.	tmpzr1t_l9r_go_relaxed.owl	regulation of protein monoubiquitylation|regulation of protein monoubiquitinylation							ppm	2013-12-02T09:58:56Z					biological_process											owl:Class	
GO:0008198	biolink:NamedThing	ferrous iron binding	Binding to a ferrous iron ion, Fe(II).	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1900936	biolink:NamedThing	negative regulation of nonadec-1-ene biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of nonadec-1-ene biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	inhibition of nonadec-1-ene formation|downregulation of nonadec-1-ene synthesis|inhibition of nonadec-1-ene biosynthesis|negative regulation of nonadec-1-ene anabolism|down-regulation of nonadec-1-ene anabolism|negative regulation of nonadec-1-ene synthesis|down-regulation of nonadec-1-ene synthesis|down regulation of nonadec-1-ene synthesis|down-regulation of nonadec-1-ene biosynthesis|down regulation of nonadec-1-ene biosynthesis|inhibition of nonadec-1-ene anabolism|downregulation of nonadec-1-ene anabolism|down regulation of nonadec-1-ene biosynthetic process|down-regulation of nonadec-1-ene biosynthetic process|inhibition of nonadec-1-ene biosynthetic process|downregulation of nonadec-1-ene formation|negative regulation of nonadec-1-ene biosynthesis|down regulation of nonadec-1-ene formation|down regulation of nonadec-1-ene anabolism|down-regulation of nonadec-1-ene formation|downregulation of nonadec-1-ene biosynthetic process|downregulation of nonadec-1-ene biosynthesis|negative regulation of nonadec-1-ene formation|inhibition of nonadec-1-ene synthesis							tt	2012-06-14T03:13:56Z					biological_process											owl:Class	
GO:0099093	biolink:NamedThing	calcium export from the mitochondrion	A process in which a calcium ion (Ca2+) is transported out of the mitochondrial matrix, and into the cytosol.	tmpzr1t_l9r_go_relaxed.owl	mitochondrial calcium release|calcium ion transmembrane export from mitochondrion|mitochondrial calcium ion export													biological_process											owl:Class	
GO:1901660	biolink:NamedThing	calcium ion export	The directed movement of calcium ion out of a cell or organelle.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-11-20T14:33:07Z					biological_process											owl:Class	
GO:1902855	biolink:NamedThing	regulation of non-motile cilium assembly	Any process that modulates the frequency, rate or extent of non-motile cilium assembly.	tmpzr1t_l9r_go_relaxed.owl	regulation of nonmotile primary cilium assembly|regulation of sensory cilium biogenesis|regulation of nonmotile primary cilia assembly|regulation of sensory cilium assembly|regulation of immotile primary cilium assembly							kmv	2014-04-02T15:41:57Z					biological_process											owl:Class	
GO:1902873	biolink:NamedThing	negative regulation of horizontal cell localization	Any process that stops, prevents or reduces the frequency, rate or extent of horizontal cell localization.	tmpzr1t_l9r_go_relaxed.owl	down regulation of horizontal cell localization|inhibition of horizontal cell localisation|inhibition of laminar positioning of retinal horizontal cell|inhibition of horizontal cell localization|downregulation of horizontal cell positioning|negative regulation of retinal horizontal cell positioning|downregulation of horizontal cell localization|down-regulation of laminar positioning of retinal horizontal cell|inhibition of horizontal cell positioning|downregulation of laminar positioning of retinal horizontal cell|negative regulation of horizontal cell localisation|negative regulation of laminar positioning of retinal horizontal cell|down-regulation of horizontal cell localisation|negative regulation of horizontal cell positioning|downregulation of horizontal cell localisation|down regulation of laminar positioning of retinal horizontal cell|down-regulation of horizontal cell localization|downregulation of retinal horizontal cell positioning|inhibition of retinal horizontal cell positioning|down regulation of horizontal cell localisation|down-regulation of retinal horizontal cell positioning|down regulation of retinal horizontal cell positioning|down regulation of horizontal cell positioning|down-regulation of horizontal cell positioning							mr	2014-04-03T15:25:03Z					biological_process											owl:Class	
GO:0003096	biolink:NamedThing	renal sodium ion transport	The directed movement of sodium ions (Na+) by the renal system.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0039585	biolink:NamedThing	PKR-mediated signaling	A series of reactions in which a signal is passed on to downstream proteins within the cell via PKR (also known as EIF2AK3), an intracellular protein kinase that is activated by stress signals or upon binding to double-stranded RNA (dsRNA), followed by autophosphorylation. PKR plays a role in the antiviral response, phosphorylating proteins such as the translation initiation factor eIF2 to inhibit protein synthesis during viral infection. Begins with activation of PKR activity, and ends with regulation of a downstream cellular process, e.g. regulation of transcription or inhibition of translation.	tmpzr1t_l9r_go_relaxed.owl	EIF2AK3 signal transduction|PKR signal transduction|PKR signaling pathway|signaling through PKR|EIF2AK3/PERK signaling							bf	2012-05-02T04:15:10Z					biological_process											owl:Class	
GO:0046115	biolink:NamedThing	guanosine catabolic process	The chemical reactions and pathways resulting in the breakdown of guanine, guanine riboside, a nucleoside with a wide species distribution.	tmpzr1t_l9r_go_relaxed.owl	guanosine breakdown|guanosine degradation|guanosine catabolism|guanosine phosphorolysis											GO:0006160		biological_process											owl:Class	
GO:2000275	biolink:NamedThing	regulation of oxidative phosphorylation uncoupler activity	Any process that modulates the frequency, rate or extent of oxidative phosphorylation uncoupler activity.	tmpzr1t_l9r_go_relaxed.owl	regulation of mitochondrial uncoupling protein activity|regulation of uncoupling protein activity							mah	2010-12-07T12:14:54Z					biological_process											owl:Class	
GO:0099108	biolink:NamedThing	potassium channel activator activity involved in G protein-coupled receptor signaling pathway	Activation potassium ion channel activity via direct interaction with a potassium ion channel during G protein-coupled receptor signaling.	tmpzr1t_l9r_go_relaxed.owl	potassium channel activator activity involved in G-protein coupled receptor signaling pathway					Examples include G-protein beta-gamma complexes that bind to and activate potassium channels.								molecular_function											owl:Class	
GO:1901850	biolink:NamedThing	7,8-didemethyl-8-hydroxy-5-deazariboflavin metabolic process	The chemical reactions and pathways involving 7,8-didemethyl-8-hydroxy-5-deazariboflavin.	tmpzr1t_l9r_go_relaxed.owl	coenzyme F0 metabolism|7,8-didemethyl-8-hydroxy-5-deazariboflavin metabolism							yaf	2013-01-28T11:38:32Z					biological_process											owl:Class	
GO:2000670	biolink:NamedThing	positive regulation of dendritic cell apoptotic process	Any process that activates or increases the frequency, rate or extent of dendritic cell apoptotic process.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of dendritic cell apoptosis							pr	2011-05-09T07:34:26Z					biological_process											owl:Class	
GO:1903425	biolink:NamedThing	fluoride transmembrane transporter activity	Enables the transfer of fluoride from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl								mcc	2014-09-09T21:27:55Z					molecular_function											owl:Class	
GO:0050318	biolink:NamedThing	tannase activity	Catalysis of the reaction: digallate + H(2)O = 2 gallate + H(+).	tmpzr1t_l9r_go_relaxed.owl	tannase S|tannin acylhydrolase activity|tannin acetylhydrolase activity				KEGG_REACTION:R00053|MetaCyc:TANNASE-RXN|EC:3.1.1.20|RHEA:16365									molecular_function											owl:Class	
GO:0033885	biolink:NamedThing	10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity	Catalysis of the reaction: (9S,10S)-10-hydroxy-9-(phosphonooxy)octadecanoate + H(2)O = (9S,10S)-9,10-dihydroxyoctadecanoate + phosphate.	tmpzr1t_l9r_go_relaxed.owl	lipid-phosphate phosphatase activity|dihydroxy fatty acid phosphatase activity|sEH|soluble epoxide hydrolase activity|(9S,10S)-10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity|hydroxy lipid phosphatase activity|(9S,10S)-10-hydroxy-9-(phosphonooxy)octadecanoate phosphohydrolase activity|hydroxy fatty acid phosphatase activity				RHEA:16537|EC:3.1.3.76|MetaCyc:3.1.3.76-RXN|KEGG_REACTION:R07582									molecular_function											owl:Class	
GO:0001405	biolink:NamedThing	PAM complex, Tim23 associated import motor	Protein complex located on the matrix side of the mitochondrial inner membrane and associated with the TIM23 mitochondrial import inner membrane translocase complex (GO:0005744); ATPase motor activity to drive import of proteins into the mitochondrial matrix.	tmpzr1t_l9r_go_relaxed.owl	mitochondrial import motor|presequence translocase-associated import motor|PAM complex|pre-sequence translocase-associated import motor													cellular_component											owl:Class	
GO:0005664	biolink:NamedThing	nuclear origin of replication recognition complex	A multisubunit complex that is located at the replication origins of a chromosome in the nucleus.	tmpzr1t_l9r_go_relaxed.owl	nuclear ORC|eukaryotic ORC													cellular_component											owl:Class	
GO:0000808	biolink:NamedThing	origin recognition complex	A multisubunit complex that is located at the replication origins of a chromosome.	tmpzr1t_l9r_go_relaxed.owl	origin of replication recognition complex|ORC				Wikipedia:Origin_recognition_complex									cellular_component											owl:Class	
GO:0052042	biolink:NamedThing	positive regulation by symbiont of host programmed cell death	Any process in which an organism activates, maintains or increases the frequency, rate or extent of programmed cell death in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	pathogenesis|upregulation by symbiont of host programmed cell death|induction by organism of non-apoptotic programmed cell death in other organism during symbiotic interaction|activation by symbiont of host programmed cell death|induction by organism of programmed cell death in other organism involved in symbiotic interaction|stimulation by symbiont of host programmed cell death|induction by organism of programmed cell death in other organism during symbiotic interaction|activation by organism of non-apoptotic programmed cell death in other organism|enhancement of host programmed cell death|induction of non-apoptotic programmed cell death by other organism|activation by organism of programmed cell death in other organism during symbiotic interaction|positive regulation by symbiont of host non-apoptotic programmed cell death|enhancement of host programmed cell death by organism|induction by symbiont of host programmed cell death|activation by organism of host programmed cell death											GO:0052044|GO:0012504|GO:0052397|GO:0052045|GO:0052153|GO:0052400		biological_process											owl:Class	
GO:0015483	biolink:NamedThing	long-chain fatty acid transporting porin activity	Enables the transfer of long-chain fatty acids from one side of a membrane to the other. A long-chain fatty acid is a fatty acid with a chain length between C13 and C22. This transporter is a porin and so enables the energy independent passage of substances, sized less than 1000 Da, across a membrane. The transmembrane portions of porins consist exclusively of beta-strands which form a beta-barrel. They are found in the outer membranes of Gram-negative bacteria, mitochondria, plastids and possibly acid-fast Gram-positive bacteria.	tmpzr1t_l9r_go_relaxed.owl					TC:1.B.9.1.1									molecular_function											owl:Class	
GO:1905533	biolink:NamedThing	negative regulation of leucine import across plasma membrane	Any process that stops, prevents or reduces the frequency, rate or extent of leucine import across plasma membrane.	tmpzr1t_l9r_go_relaxed.owl	inhibition of leucine import into cell|inhibition of L-leucine import into cell|downregulation of leucine import into cell|down regulation of leucine import into cell|negative regulation of leucine import into cell|negative regulation of L-leucine import into cell|down-regulation of leucine import into cell|down regulation of L-leucine import into cell|downregulation of L-leucine import into cell|down-regulation of L-leucine import into cell							vw	2016-10-05T21:08:01Z			GO:1903129		biological_process											owl:Class	
GO:1905532	biolink:NamedThing	regulation of leucine import across plasma membrane	Any process that modulates the frequency, rate or extent of leucine import across plasma membrane.	tmpzr1t_l9r_go_relaxed.owl	regulation of leucine import into cell|regulation of L-leucine import into cell							vw	2014-06-25T13:09:51Z			GO:1903128		biological_process											owl:Class	
GO:0007185	biolink:NamedThing	transmembrane receptor protein tyrosine phosphatase signaling pathway	A series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell where the receptor possesses protein tyrosine phosphatase activity, and ending with regulation of a downstream cellular process, e.g. transcription.	tmpzr1t_l9r_go_relaxed.owl	transmembrane receptor protein tyrosine phosphatase signalling pathway													biological_process											owl:Class	
GO:0007167	biolink:NamedThing	enzyme linked receptor protein signaling pathway	Any series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell, where the receptor possesses catalytic activity or is closely associated with an enzyme such as a protein kinase, and ending with regulation of a downstream cellular process, e.g. transcription.	tmpzr1t_l9r_go_relaxed.owl	enzyme linked receptor protein signalling pathway													biological_process											owl:Class	
GO:0033151	biolink:NamedThing	V(D)J recombination	The process in which immune receptor V, D, and J, or V and J gene segments, depending on the specific receptor, are recombined within a single locus utilizing the conserved heptamer and nonomer recombination signal sequences (RSS).	tmpzr1t_l9r_go_relaxed.owl	V-J joining|V(D)J joining|V-J recombination|V-D-J recombination|V-D-J joining				Wikipedia:V(D)J_recombination									biological_process											owl:Class	
GO:0030186	biolink:NamedThing	melatonin metabolic process	The chemical reactions and pathways involving melatonin (N-acetyl-5-methoxytryptamine).	tmpzr1t_l9r_go_relaxed.owl	melatonin metabolism													biological_process											owl:Class	
GO:0000947	biolink:NamedThing	amino acid catabolic process to alcohol via Ehrlich pathway	The chemical reactions and pathways involving the catabolism of amino acids to produce alcohols with one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of alcohols, often collectively referred to as fusel alcohols. Depending on the redox state of the cells, carboxylic acid derivatives may be produced instead of alcohols.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0061115	biolink:NamedThing	lung proximal/distal axis specification	The establishment, maintenance and elaboration of the proximal/distal axis of the lung. The proximal/distal axis of the lung is defined by a line that runs from the trachea to the alveoli.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-05-10T12:30:40Z					biological_process											owl:Class	
GO:0008071	biolink:NamedThing	maternal determination of dorsal/ventral axis, ovarian follicular epithelium, soma encoded	Polarization of the ovarian follicle cells along the dorsal-ventral axis by a gene product encoded by somatic cells. An example of this process is found in Drosophila melanogaster.	tmpzr1t_l9r_go_relaxed.owl	maternal determination of dorsoventral axis, ovarian follicular epithelium, soma encoded|maternal determination of dorsal-ventral axis, ovarian follicular epithelium, soma encoded|maternal determination of dorsal/ventral axis, follicular epithelium, soma encoded													biological_process											owl:Class	
GO:1902240	biolink:NamedThing	positive regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator	Any process that activates or increases the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator.	tmpzr1t_l9r_go_relaxed.owl	upregulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator|up-regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator|activation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator|up regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator							pr	2013-06-19T14:00:44Z					biological_process											owl:Class	
GO:1902220	biolink:NamedThing	positive regulation of intrinsic apoptotic signaling pathway in response to osmotic stress	Any process that activates or increases the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to osmotic stress.	tmpzr1t_l9r_go_relaxed.owl	up regulation of intrinsic apoptotic signaling pathway in response to osmotic stress|upregulation of intrinsic apoptotic signaling pathway in response to osmotic stress|activation of intrinsic apoptotic signaling pathway in response to osmotic stress|up-regulation of intrinsic apoptotic signaling pathway in response to osmotic stress							rl	2013-06-13T10:19:18Z					biological_process											owl:Class	
GO:1900015	biolink:NamedThing	regulation of cytokine production involved in inflammatory response	Any process that modulates the frequency, rate or extent of cytokine production involved in inflammatory response.	tmpzr1t_l9r_go_relaxed.owl	regulation of cytokine production involved in acute inflammatory response							rph	2012-01-11T09:34:27Z					biological_process											owl:Class	
GO:0048556	biolink:NamedThing	microsporocyte nucleus	The nucleus of the microsporocyte. The microsporocyte is a diploid cell in which meiosis will occur, resulting in four microspores. A microspore is a spore that, in vascular plants, gives rise to a male gametophyte.	tmpzr1t_l9r_go_relaxed.owl	microspore mother cell nucleus|pollen mother cell nucleus											GO:0043074		cellular_component											owl:Class	
GO:0060178	biolink:NamedThing	regulation of exocyst localization	Any process that modulates the localization of exocysts. An exocyst is a protein complex peripherally associated with the plasma membrane that determines where vesicles dock and fuse.	tmpzr1t_l9r_go_relaxed.owl	regulation of exocyst localisation													biological_process											owl:Class	
GO:0016897	biolink:NamedThing	exoribonuclease activity, producing 3'-phosphomonoesters	Catalysis of the hydrolysis of ester linkages within ribonucleic acids by removing nucleotide residues from the 3' or 5' end to yield 3' phosphomonoesters.	tmpzr1t_l9r_go_relaxed.owl					EC:3.1.14.-									molecular_function											owl:Class	
GO:0016797	biolink:NamedThing	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters	Catalysis of the hydrolysis of ester linkages within nucleic acids by removing nucleotide residues from the 3' or 5' end to yield 3' phosphomonoesters.	tmpzr1t_l9r_go_relaxed.owl					EC:3.1.16.-	Note that this activity can catalyze cleavage of DNA or RNA.								molecular_function											owl:Class	
GO:0102841	biolink:NamedThing	1-18:1-2-16:2-monogalactosyldiacylglycerol synthase activity	Catalysis of the reaction: 1-18:1-2-16:1-monogalactosyldiacylglycerol + O2 + a reduced electron acceptor <=> 1-18:1-2-16:2-monogalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor.	tmpzr1t_l9r_go_relaxed.owl					EC:1.14.19.23|MetaCyc:RXN-8302									molecular_function											owl:Class	
GO:0018273	biolink:NamedThing	protein-chromophore linkage via peptidyl-N6-retinal-L-lysine	The modification of peptidyl-lysine to form N6-retinal-L-lysine.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0120									biological_process											owl:Class	
GO:0009260	biolink:NamedThing	ribonucleotide biosynthetic process	The chemical reactions and pathways resulting in the formation of a ribonucleotide, a compound consisting of ribonucleoside (a base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.	tmpzr1t_l9r_go_relaxed.owl	ribonucleotide biosynthesis|ribonucleotide anabolism|ribonucleotide formation|ribonucleotide synthesis													biological_process											owl:Class	
GO:0038110	biolink:NamedThing	interleukin-2-mediated signaling pathway	A series of molecular signals initiated by the binding of interleukin-2 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.	tmpzr1t_l9r_go_relaxed.owl	interleukin-2-mediated signalling pathway|IL-2-mediated signaling pathway							bf	2012-03-22T10:18:29Z					biological_process											owl:Class	
GO:0071197	biolink:NamedThing	Kv4.2-Kv4.3 channel complex	A voltage-gated potassium channel complex that contains the Kv alpha subunits 4.2 and 4.3.	tmpzr1t_l9r_go_relaxed.owl					CORUM:609			mah	2009-11-23T05:00:33Z					cellular_component											owl:Class	
GO:2000451	biolink:NamedThing	positive regulation of CD8-positive, alpha-beta T cell extravasation	Any process that activates or increases the frequency, rate or extent of CD8-positive, alpha-beta T cell extravasation.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-03-04T10:42:14Z					biological_process											owl:Class	
GO:0036319	biolink:NamedThing	mating-type M-factor pheromone receptor activity	Combining with the mating-type peptide pheromone M-factor and transmitting the signal across the membrane to initiate a change in cell activity. M-factor is a nine-membered oligopeptide that consists of tyrosyl, threonyl, prolyl, lysyl, valyl, prolyl, tyrosyl, methionyl and methyl S-farnesylcysteinate residues joined in sequence, and is a peptide pheromone released by Schizosaccharomyces pombe cells of the cellular mating type Minus.	tmpzr1t_l9r_go_relaxed.owl	M-factor receptor activity|M-factor mating pheromone receptor activity							bf	2012-08-30T16:51:12Z					molecular_function											owl:Class	
GO:0048171	biolink:NamedThing	negative regulation of long-term neuronal synaptic plasticity	A process that decreases long-term neuronal synaptic plasticity, the ability of neuronal synapses to change long-term as circumstances require. Long-term neuronal synaptic plasticity generally involves increase or decrease in actual synapse numbers.	tmpzr1t_l9r_go_relaxed.owl	down regulation of long-term neuronal synaptic plasticity|inhibition of long-term neuronal synaptic plasticity|down-regulation of long-term neuronal synaptic plasticity|downregulation of long-term neuronal synaptic plasticity					Note that the syntax of the definition of this term is different from the usual regulation syntax because it describes regulation of a trait rather than regulation of a process.								biological_process											owl:Class	
GO:0106115	biolink:NamedThing	negative regulation of mitotic cohesin dsDNA (leading strand) loading	Any process that stops, prevents or reduces the frequency, rate or extent of mitotic cohesin dsDNA (leading strand) loading.	tmpzr1t_l9r_go_relaxed.owl								hjd	2018-04-18T14:50:12Z					biological_process											owl:Class	
GO:0070825	biolink:NamedThing	micropyle	An external encapsulating structure part of the chorion. A single cone-shaped specialization that forms an opening in the egg chorion that allows sperm entry into the egg prior to fertilization.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-07-21T05:33:09Z					cellular_component											owl:Class	
GO:0009028	biolink:NamedThing	tartronate-semialdehyde synthase activity	Catalysis of the reaction: 2 glyoxylate + H(+) = 2-hydroxy-3-oxopropanoate + CO(2).	tmpzr1t_l9r_go_relaxed.owl	glyoxylate carboligase activity|glyoxylate carbo-ligase activity|tartronic semialdehyde carboxylase activity|glyoxylate carboxy-lyase (dimerizing; tartronate-semialdehyde-forming)|tartronate semialdehyde carboxylase activity|glyoxylate carboxy-lyase (dimerizing)|glyoxalate carboligase activity|glyoxylic carbo-ligase activity|hydroxymalonic semialdehyde carboxylase activity				EC:4.1.1.47|RHEA:10136|KEGG_REACTION:R00013|MetaCyc:GLYOCARBOLIG-RXN									molecular_function											owl:Class	
GO:2000107	biolink:NamedThing	negative regulation of leukocyte apoptotic process	Any process that stops, prevents, or reduces the frequency, rate or extent of leukocyte apoptotic process.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of leukocyte apoptosis							mah	2010-09-15T01:42:09Z					biological_process											owl:Class	
GO:0042118	biolink:NamedThing	endothelial cell activation	The change in morphology and behavior of an endothelial cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0005115	biolink:NamedThing	receptor tyrosine kinase-like orphan receptor binding	Binding to a receptor tyrosine kinase-like orphan receptor (Ror).	tmpzr1t_l9r_go_relaxed.owl	receptor tyrosine kinase-like orphan receptor ligand|Ror ligand|Ror binding													molecular_function											owl:Class	
GO:0017161	biolink:NamedThing	inositol-1,3,4-trisphosphate 4-phosphatase activity	Catalysis of the reaction: D-myo-inositol 1,3,4-trisphosphate + H2O = myo-inositol 1,3-bisphosphate + phosphate.	tmpzr1t_l9r_go_relaxed.owl					RHEA:43392|Reactome:R-HSA-1855180									molecular_function											owl:Class	
GO:0004789	biolink:NamedThing	thiamine-phosphate diphosphorylase activity	Catalysis of the reaction: 4-amino-2-methyl-5-diphosphomethylpyrimidine + 4-methyl-5-(2-phosphoethyl)-thiazole + H(+) = diphosphate + thiamine phosphate.	tmpzr1t_l9r_go_relaxed.owl	thiamine phosphate pyrophosphorylase activity|thiamine-phosphate pyrophosphorylase activity|thiamine-phosphate synthase activity|thiamin-phosphate diphosphorylase activity|TMP diphosphorylase activity|thiamine monophosphate pyrophosphorylase activity|thiamin-phosphate pyrophosphorylase activity|TMP pyrophosphorylase activity|TMP-PPase activity|2-methyl-4-amino-5-hydroxymethylpyrimidine-diphosphate:4-methyl-5-(2-phosphoethyl)thiazole 2-methyl-4-aminopyrimidine-5-methenyltransferase activity				RHEA:22328|KEGG_REACTION:R03223|MetaCyc:THI-P-SYN-RXN|EC:2.5.1.3									molecular_function											owl:Class	
GO:0034375	biolink:NamedThing	high-density lipoprotein particle remodeling	The acquisition, loss or modification of a protein or lipid within a high-density lipoprotein particle, including the hydrolysis of triglyceride by hepatic lipase, with the subsequent loss of free fatty acid, and the transfer of cholesterol esters from LDL to a triglyceride-rich lipoprotein particle by cholesteryl ester transfer protein (CETP), with the simultaneous transfer of triglyceride to LDL.	tmpzr1t_l9r_go_relaxed.owl	HDL remodeling													biological_process											owl:Class	
GO:1990747	biolink:NamedThing	pancreatic trypsinogen secretion	The regulated release of trypsinogen from the cells of the exocrine pancreas.	tmpzr1t_l9r_go_relaxed.owl	pancreatic trypsinogen release							sl	2015-05-15T17:41:25Z					biological_process											owl:Class	
GO:0099620	biolink:NamedThing	UDP-4-amino-4-deoxy-L-arabinose aminotransferase	Catalysis of the reaction: UDP-4-amino-4-deoxy-beta-L-arabinopyranose + 2-oxoglutarate = UDP-beta-L-threo-pentapyranos-4-ulose + L-glutamate.	tmpzr1t_l9r_go_relaxed.owl	UDP-L-Ara4N transaminase|UDP-(beta-L-threo-pentapyranosyl-4''-ulose diphosphate) aminotransferase|UDP-Ara4O aminotransferase|UDP-4-amino-4-deoxy-L-arabinose---oxoglutarate aminotransferase|UDP-4-amino-4-deoxy-beta-L-arabinose:2-oxoglutarate aminotransferase				EC:2.6.1.87|RHEA:24710									molecular_function											owl:Class	
GO:1990343	biolink:NamedThing	heterochromatin domain	A region of heterochromatin that is formed dynamically under specific growth conditions by a process that requires RNAi, and is enriched in histone H3 methylated on lysine 9 (H3K9me).	tmpzr1t_l9r_go_relaxed.owl	HOOD					An example of this type of heterochromatin is found in Schizosaccharomyces pombe, where heterochromatin domains preferentially assemble at sexual differentiation genes and retrotransposons.		mah	2014-03-21T15:40:48Z					cellular_component											owl:Class	
GO:0045984	biolink:NamedThing	negative regulation of pyrimidine nucleobase metabolic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving pyrimidine nucleobases.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of pyrimidine base metabolic process|negative regulation of pyrimidine base metabolic process|negative regulation of pyrimidine base metabolism|down regulation of pyrimidine base metabolic process|downregulation of pyrimidine base metabolic process|inhibition of pyrimidine base metabolic process													biological_process											owl:Class	
GO:1990256	biolink:NamedThing	signal clustering	Grouping of multiple copies of a signal at a cellular location. May promote receptor clustering and alter the signal transduction response.	tmpzr1t_l9r_go_relaxed.owl	ligand clustering							tb	2013-12-18T01:13:59Z					biological_process											owl:Class	
GO:0099149	biolink:NamedThing	regulation of postsynaptic neurotransmitter receptor internalization	Any process that modulates the frequency, rate or extent of endocytosis of neurotransmitter receptor at the postsynapse.	tmpzr1t_l9r_go_relaxed.owl	regulation of postsynaptic neurotransmitter receptor endocytosis							dos	2017-07-05T13:13:49Z					biological_process											owl:Class	
GO:0008925	biolink:NamedThing	maltose O-acetyltransferase activity	Catalysis of the reaction: acetyl-CoA + maltose = CoA + acetyl-maltose.	tmpzr1t_l9r_go_relaxed.owl	maltose transacetylase activity|acetyl-CoA:maltose O-acetyltransferase activity				MetaCyc:MALTACETYLTRAN-RXN|EC:2.3.1.79|RHEA:10456									molecular_function											owl:Class	
GO:1990167	biolink:NamedThing	protein K27-linked deubiquitination	A protein deubiquitination process in which a K27-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 27 of the ubiquitin monomers, is removed from a protein.	tmpzr1t_l9r_go_relaxed.owl								sp	2013-08-14T11:15:24Z					biological_process											owl:Class	
GO:1900032	biolink:NamedThing	regulation of trichome patterning	Any process that modulates the frequency, rate or extent of trichome patterning.	tmpzr1t_l9r_go_relaxed.owl	regulation of trichome spacing|regulation of trichome pattern biosynthesis|regulation of trichome distribution|regulation of trichome pattern specification|regulation of trichome pattern formation							tb	2012-01-13T11:10:46Z					biological_process											owl:Class	
GO:0018956	biolink:NamedThing	phenanthrene catabolic process via trans-9(R),10(R)-dihydrodiolphenanthrene	The chemical reactions and pathways resulting in the breakdown of phenanthrene, a tricyclic aromatic hydrocarbon, where trans-9(R),10(R)-dihydrodiolphenanthrene is the principal intermediate metabolite.	tmpzr1t_l9r_go_relaxed.owl	phenanthrene degradation via trans-9(R),10(R)-dihydrodiolphenanthrene|phenanthrene breakdown via trans-9(R),10(R)-dihydrodiolphenanthrene				UM-BBD_pathwayID:pha3									biological_process											owl:Class	
GO:0033851	biolink:NamedThing	lavandulyl diphosphate synthase activity	Catalysis of the reaction: 2 dimethylallyl diphosphate = diphosphate + lavandulyl diphosphate.	tmpzr1t_l9r_go_relaxed.owl	dimethylallyl-diphosphate:dimethylallyl-diphosphate dimethylallyltransferase (lavandulyl-diphosphate-forming) activity|FDS-5				KEGG_REACTION:R08950|MetaCyc:2.5.1.69-RXN|RHEA:21676|EC:2.5.1.69									molecular_function											owl:Class	
GO:0018413	biolink:NamedThing	peptidyl-serine O-glucuronidation	The O-glucuronidation of peptidyl-serine to form peptidyl-O3-D-glucuronyl-L-serine.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0291									biological_process											owl:Class	
GO:0019176	biolink:NamedThing	dihydroneopterin monophosphate phosphatase activity	Catalysis of the reaction: dihydroneopterin monophosphate = dihydroneopterin + phosphate.	tmpzr1t_l9r_go_relaxed.owl	dihydroneopterin monophosphate dephosphorylase activity				RHEA:25306|MetaCyc:DIHYDRONEOPTERIN-MONO-P-DEPHOS-RXN									molecular_function											owl:Class	
GO:0047313	biolink:NamedThing	aromatic-amino-acid-glyoxylate transaminase activity	Catalysis of the reaction: glyoxylate + an aromatic amino acid = L-glycine + an aromatic oxo acid.	tmpzr1t_l9r_go_relaxed.owl	aromatic-amino-acid:glyoxylate aminotransferase activity|aromatic-amino-acid-glyoxylate aminotransferase activity|aromatic-amino-acid--glyoxylate aminotransferase activity				RHEA:10900|EC:2.6.1.60|MetaCyc:2.6.1.60-RXN									molecular_function											owl:Class	
GO:0106310	biolink:NamedThing	protein serine kinase activity	Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/20114			RHEA:17989	Note that this term is to annotate proteins the specifically phosphorylate a serine residue on a protein. An example is human PIKFYVE (UniProt:Q9Y2I7). For dual specificity protein kinases, use 'protein serine/threonine kinase activity' ; GO:0004712.		hjd	2020-09-22T20:01:17Z					molecular_function											owl:Class	
GO:0050596	biolink:NamedThing	vinorine hydroxylase activity	Catalysis of the reaction: H(+) + NADPH + O(2) + vinorine = H(2)O + NADP(+) + vomilenine.	tmpzr1t_l9r_go_relaxed.owl	vinorine,NADPH:oxygen oxidoreductase (21alpha-hydroxylating)				EC:1.14.14.104|RHEA:17257|KEGG_REACTION:R05877|MetaCyc:1.14.13.75-RXN									molecular_function											owl:Class	
GO:0051230	biolink:NamedThing	spindle disassembly	The controlled breakdown of the spindle, the array of microtubules and associated molecules that serves to move duplicated chromosomes apart.	tmpzr1t_l9r_go_relaxed.owl	spindle breakdown|spindle catabolism|spindle degradation													biological_process											owl:Class	
GO:0006781	biolink:NamedThing	succinyl-CoA pathway	The chemical reactions that utilize succinyl-CoA in the synthesis of protoporphyrin IX.	tmpzr1t_l9r_go_relaxed.owl	biosynthesis of protoporphyrin IX via succinyl CoA|biosynthetic process of protoporphyrin IX via succinyl CoA|succinyl CoA pathway|biosynthesis of protoporphyrin IX via succinyl-CoA|biosynthetic process of protoporphyrin IX via succinyl-CoA													biological_process											owl:Class	
GO:0034434	biolink:NamedThing	sterol esterification	A lipid modification process in which a sterol ester is formed by the combination of a carboxylic acid (often a fatty acid) and a sterol molecule (e.g. cholesterol).	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0034433	biolink:NamedThing	steroid esterification	A lipid modification process in which a steroid ester is formed by the combination of a carboxylic acid (often a fatty acid) and a steroid molecule (e.g. cholesterol).	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1901120	biolink:NamedThing	tobramycin catabolic process	The chemical reactions and pathways resulting in the breakdown of tobramycin.	tmpzr1t_l9r_go_relaxed.owl	tobramycin breakdown|tobramycin catabolism|tobramycin degradation							yaf	2012-07-11T03:15:43Z					biological_process											owl:Class	
GO:0035692	biolink:NamedThing	macrophage migration inhibitory factor receptor complex	A protein complex that binds macrophage migration inhibitory factor. Comprises CD74 and CD44 cell surface proteins.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-02-25T11:33:15Z					cellular_component											owl:Class	
GO:1902526	biolink:NamedThing	negative regulation of protein monoubiquitination	Any process that stops, prevents or reduces the frequency, rate or extent of protein monoubiquitination.	tmpzr1t_l9r_go_relaxed.owl	down regulation of protein monoubiquitination|down-regulation of protein monoubiquitinylation|down-regulation of protein monoubiquitination|down-regulation of protein monoubiquitylation|negative regulation of protein monoubiquitinylation|down regulation of protein monoubiquitinylation|down regulation of protein monoubiquitylation|downregulation of protein monoubiquitinylation|downregulation of protein monoubiquitination|inhibition of protein monoubiquitination|downregulation of protein monoubiquitylation|inhibition of protein monoubiquitinylation|negative regulation of protein monoubiquitylation|inhibition of protein monoubiquitylation							ppm	2013-12-02T09:59:05Z					biological_process											owl:Class	
GO:0001172	biolink:NamedThing	transcription, RNA-templated	The cellular synthesis of RNA on a template of RNA.	tmpzr1t_l9r_go_relaxed.owl	transcription, RNA-dependent							krc	2011-03-14T03:54:46Z					biological_process											owl:Class	
GO:0047664	biolink:NamedThing	aminoimidazolase activity	Catalysis of the reaction:4-aminoimidazole + H20 = imidazol-4-one + NH(3).	tmpzr1t_l9r_go_relaxed.owl	4-aminoimidazole aminohydrolase activity|4-aminoimidazole hydrolase activity				EC:3.5.4.8|RHEA:22348|MetaCyc:R13-RXN									molecular_function											owl:Class	
GO:0030446	biolink:NamedThing	hyphal cell wall	The cell wall surrounding a fungal hypha.	tmpzr1t_l9r_go_relaxed.owl						See also the Fungal Anatomy Ontology term 'hypha ; FAO:0001001'.								cellular_component											owl:Class	
GO:0031620	biolink:NamedThing	regulation of fever generation	Any process that modulates the rate or extent of fever generation.	tmpzr1t_l9r_go_relaxed.owl	regulation of pyrexia													biological_process											owl:Class	
GO:1902642	biolink:NamedThing	negative regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolism|downregulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate degradation|down-regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate degradation|inhibition of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate breakdown|inhibition of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process|downregulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process|negative regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolism|down regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolism|down-regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process|negative regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate degradation|downregulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolism|down regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate breakdown|inhibition of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate degradation|negative regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate breakdown|down-regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate breakdown|down regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate degradation|downregulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate breakdown|down regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process|inhibition of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolism							di	2014-01-21T17:54:23Z					biological_process											owl:Class	
GO:0045454	biolink:NamedThing	cell redox homeostasis	Any process that maintains the redox environment of a cell or compartment within a cell.	tmpzr1t_l9r_go_relaxed.owl	regulation of cell redox homeostasis|regulation of redox homeostasis				Wikipedia:Redox							GO:0030503|GO:0045868|GO:0045867		biological_process											owl:Class	
GO:0015556	biolink:NamedThing	C4-dicarboxylate transmembrane transporter activity	Enables the transfer of C4-dicarboxylate from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:2000037	biolink:NamedThing	regulation of stomatal complex patterning	Any process that modulates the frequency, rate or extent of stomatal complex patterning.	tmpzr1t_l9r_go_relaxed.owl								tb	2010-08-05T11:35:47Z					biological_process											owl:Class	
GO:0070114	biolink:NamedThing	organellar chromatophore outer membrane	The outer, i.e. cytoplasm-facing, of the two lipid bilayers surrounding an organellar chromatophore.	tmpzr1t_l9r_go_relaxed.owl	Paulinella-type chromatophore outer membrane													cellular_component											owl:Class	
GO:0010572	biolink:NamedThing	positive regulation of platelet activation	Any process that increases the rate or frequency of platelet activation. Platelet activation is a series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1902702	biolink:NamedThing	hexose catabolic process to propan-2-ol	The chemical reactions and pathways resulting in the breakdown of hexose to propan-2-ol.	tmpzr1t_l9r_go_relaxed.owl	hexose catabolic process to isopropyl alcohol|hexose breakdown to propan-2-ol|hexose catabolism to propan-2-ol|hexose degradation to propan-2-ol|solventogenesis|hexose catabolic process to isopropanol							tb	2014-02-19T18:42:54Z			GO:1990283		biological_process											owl:Class	
GO:1900770	biolink:NamedThing	fumitremorgin B metabolic process	The chemical reactions and pathways involving fumitremorgin B.	tmpzr1t_l9r_go_relaxed.owl	Lanosulin metabolism|Lanosulin metabolic process|fumitremorgin B metabolism							di	2012-06-04T09:25:18Z					biological_process											owl:Class	
GO:0120006	biolink:NamedThing	regulation of glutamatergic neuron differentiation	Any process that modulates the frequency, rate or extent of glutamatergic neuron differentiation.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/13107						krc	2017-03-01T16:10:27Z					biological_process											owl:Class	
GO:0043884	biolink:NamedThing	CO-methylating acetyl-CoA synthase activity	Catalysis of the reaction: acetyl-CoA + corrinoid protein = CO + methylcorrinoid protein + CoA.	tmpzr1t_l9r_go_relaxed.owl	CO-methylating acetyl-coenzyme A synthase activity|ACS|acetyl-CoA synthase activity|acetyl-CoA:corrinoid protein O-acetyltransferase activity				RHEA:45212|EC:2.3.1.169|MetaCyc:ACETYLSYNCLTH-RXN									molecular_function											owl:Class	
GO:0075507	biolink:NamedThing	entry of viral genome into host nucleus via docking of viral capsid to the nuclear pore complex and injection of viral genome	Viral penetration into the host nucleus where the where a viral capsid docks on the cytoplasmic side of the nuclear pore complex (NPC) and ejects the viral genome through the pore into the nucleoplasm.	tmpzr1t_l9r_go_relaxed.owl						This mechanism is used by viruses such as Herpesvirales whose capsid is too large to enter the nuclear pore complex (NPC) pore.		jl	2011-07-26T04:52:51Z					biological_process											owl:Class	
GO:0075732	biolink:NamedThing	viral penetration into host nucleus	The crossing by the virus of the host nuclear membrane, either as naked viral genome or for small viruses as an intact capsid.	tmpzr1t_l9r_go_relaxed.owl	viral import into host nucleus|viral entry into host nucleus				VZ:989			jl	2009-05-01T02:43:16Z					biological_process											owl:Class	
GO:0018048	biolink:NamedThing	C-terminal peptidyl-proline amidation	The formation of a C-terminal peptidyl-proline amide by hydrolysis and oxidation of an interior Pro-Gly peptide in a secreted protein.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0095									biological_process											owl:Class	
GO:0004906	biolink:NamedThing	interferon-gamma receptor activity	Combining with interferon-gamma (a type II interferon) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	IFN-gamma receptor activity|type II interferon receptor activity|IFNG receptor activity													molecular_function											owl:Class	
GO:0015188	biolink:NamedThing	L-isoleucine transmembrane transporter activity	Enables the transfer of L-isoleucine from one side of a membrane to the other. L-isoleucine is (2R*,3R*)-2-amino-3-methylpentanoic acid.	tmpzr1t_l9r_go_relaxed.owl	L-isoleucine transporter activity|leucine/isoleucine/valine porter activity|leucine/valine/isoleucine permease activity|isoleucine/valine:sodium symporter activity													molecular_function											owl:Class	
GO:0046565	biolink:NamedThing	3-dehydroshikimate dehydratase activity	Catalysis of the reaction: 3-dehydroshikimate = 3,4-dihydroxybenzoate + H2O. 3,4-dihydroxybenzoate is also known as protocatechuate.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:DHSHIKIMATE-DEHYDRO-RXN|EC:4.2.1.118|RHEA:24848									molecular_function											owl:Class	
GO:1990667	biolink:NamedThing	PCSK9-AnxA2 complex	A protein complex consisting of the serine protease PCSK9 (proprotein convertase subtilisin/kexin-9) and annexin A2 (AnxA2).	tmpzr1t_l9r_go_relaxed.owl	PCSK9-Annexin A2 complex|PCSK9.AnxA2 complex|PCSK9:ANXA2 complex							bf	2015-03-02T10:33:09Z					cellular_component											owl:Class	
GO:0035007	biolink:NamedThing	regulation of melanization defense response	Any process that affects the rate, extent or location of the melanization defense response during injury or invasion.	tmpzr1t_l9r_go_relaxed.owl	regulation of melanization defence response													biological_process											owl:Class	
GO:1904595	biolink:NamedThing	positive regulation of termination of RNA polymerase II transcription	Any process that activates or increases the frequency, rate or extent of termination of RNA polymerase II transcription.	tmpzr1t_l9r_go_relaxed.owl	upregulation of transcription termination from Pol II promoter|up regulation of termination of RNA polymerase II transcription|positive regulation of RNA polymerase II transcription termination factor activity|up-regulation of RNA 3'-end formation by RNA polymerase II|activation of RNA polymerase II transcription termination|activation of RNA polymerase II transcription termination factor activity|positive regulation of RNA polymerase II transcription termination|upregulation of RNA polymerase II transcription termination|positive regulation of transcription termination from RNA polymerase II promoter|positive regulation of transcription termination from Pol II promoter|up-regulation of RNA polymerase II transcription termination factor activity|up regulation of RNA polymerase II transcription termination factor activity|upregulation of RNA 3'-end formation by RNA polymerase II|upregulation of transcription termination from RNA polymerase II promoter|up-regulation of transcription termination from Pol II promoter|up regulation of RNA 3'-end formation by RNA polymerase II|activation of transcription termination from RNA polymerase II promoter|up-regulation of RNA polymerase II transcription termination|positive regulation of RNA 3'-end formation by RNA polymerase II|up regulation of transcription termination from RNA polymerase II promoter|up-regulation of transcription termination from RNA polymerase II promoter|up-regulation of termination of RNA polymerase II transcription|up regulation of RNA polymerase II transcription termination|upregulation of RNA polymerase II transcription termination factor activity|activation of transcription termination from Pol II promoter|activation of termination of RNA polymerase II transcription|up regulation of transcription termination from Pol II promoter|activation of RNA 3'-end formation by RNA polymerase II|upregulation of termination of RNA polymerase II transcription							al	2015-08-25T08:56:14Z					biological_process											owl:Class	
GO:0075273	biolink:NamedThing	positive regulation of zygosporangium development	Any process that activates, maintains or increases the frequency, rate or extent of zygosporangium development, a process in which a fruiting body called zygosporangium is formed.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1902127	biolink:NamedThing	(-)-lariciresinol metabolic process	The chemical reactions and pathways involving (-)-lariciresinol.	tmpzr1t_l9r_go_relaxed.owl	(-)-lariciresinol metabolism							ms	2013-05-21T08:49:33Z					biological_process											owl:Class	
GO:0072665	biolink:NamedThing	protein localization to vacuole	A process in which a protein is transported to, or maintained at, a location in a vacuole.	tmpzr1t_l9r_go_relaxed.owl	protein localisation to vacuole							mah	2011-02-14T02:55:35Z					biological_process											owl:Class	
GO:0044846	biolink:NamedThing	negative regulation by symbiont of indole acetic acid levels in host	Any process in which an organism reduces the indole acetic acid levels in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	negative regulation by symbiont of auxin levels in host|negative regulation by symbiont of IAA levels in host							jl	2014-05-13T11:08:04Z					biological_process											owl:Class	
GO:1904797	biolink:NamedThing	negative regulation of core promoter binding	Any process that stops, prevents or reduces the frequency, rate or extent of core promoter binding.	tmpzr1t_l9r_go_relaxed.owl	inhibition of core promoter binding|down regulation of core promoter binding|downregulation of core promoter binding|down-regulation of core promoter binding							nc	2015-11-09T12:32:31Z					biological_process											owl:Class	
GO:0046618	biolink:NamedThing	xenobiotic export	The directed movement of a xenobiotic, a compound foreign to the organim exposed to it. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical.	tmpzr1t_l9r_go_relaxed.owl	drug export	https://github.com/geneontology/go-ontology/issues/19460												biological_process											owl:Class	
GO:0071832	biolink:NamedThing	peptide pheromone export involved in regulation of conjugation	The directed movement of a peptide pheromone out of a cell by a secretion or export pathway used solely for the export of peptide pheromones that contributes to the union or introduction of genetic information from compatible mating types that results in a genetically different individual. Conjugation requires direct cellular contact between the organisms.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-09-09T11:06:46Z					biological_process											owl:Class	
GO:0000770	biolink:NamedThing	peptide pheromone export	The directed movement of a peptide pheromone out of a cell by a secretion or export pathway used solely for the export of peptide pheromones.	tmpzr1t_l9r_go_relaxed.owl	a-factor export											GO:0007325		biological_process											owl:Class	
GO:0015158	biolink:NamedThing	raffinose transmembrane transporter activity	Enables the transfer of raffinose from one side of a membrane to the other. Raffinose occurs in plants almost as commonly as sucrose and is present in cereal grains, cotton seeds, and many legumes. It is synthesized from sucrose by transfer of a galactopyranoside from myo-inositol.	tmpzr1t_l9r_go_relaxed.owl	raffinose permease													molecular_function											owl:Class	
GO:0043719	biolink:NamedThing	2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase activity	Catalysis of the reaction: 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol + O2 + H+ = 2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinol + H2O.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:OCTAPRENYL-METHYL-METHOXY-BENZOQ-OH-RXN|EC:1.14.13.-									molecular_function											owl:Class	
GO:1902080	biolink:NamedThing	regulation of calcium ion import into sarcoplasmic reticulum	Any process that modulates the frequency, rate or extent of calcium ion import into sarcoplasmic reticulum.	tmpzr1t_l9r_go_relaxed.owl								rl	2013-04-24T16:07:50Z					biological_process											owl:Class	
GO:0034015	biolink:NamedThing	L-ribulose-5-phosphate 3-epimerase activity	Catalysis of the reaction: L-ribulose 5-phosphate = L-xylulose 5-phosphate.	tmpzr1t_l9r_go_relaxed.owl	L-xylulose 5-phosphate 3-epimerase activity|UlaE|SgaU				MetaCyc:LXULRU5P-RXN|RHEA:18497|EC:5.1.3.22									molecular_function											owl:Class	
GO:1902508	biolink:NamedThing	2-iminoacetate synthase complex	A protein complex which is capable of 2-iminoacetate synthase activity.	tmpzr1t_l9r_go_relaxed.owl	ThiH-ThiG complex							bhm	2013-11-14T16:56:44Z					cellular_component											owl:Class	
GO:0071600	biolink:NamedThing	otic vesicle morphogenesis	The process in which the anatomical structures of the otic vesicle are generated and organized. The otic vesicle is a transient embryonic structure formed during development of the vertebrate inner ear.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-02-04T04:07:27Z					biological_process											owl:Class	
GO:0016206	biolink:NamedThing	catechol O-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + a catechol = S-adenosyl-L-homocysteine + a guaiacol.	tmpzr1t_l9r_go_relaxed.owl	catechol methyltransferase activity|S-COMT (soluble form of catechol-O-methyltransferase)|COMT II|catecholamine O-methyltransferase activity|MB-COMT (membrane-bound form of catechol-O-methyltransferase)|COMT I|S-adenosyl-L-methionine:catechol O-methyltransferase activity				Reactome:R-HSA-8955010|Reactome:R-HSA-175983|MetaCyc:CATECHOL-O-METHYLTRANSFERASE-RXN|EC:2.1.1.6									molecular_function											owl:Class	
GO:0016589	biolink:NamedThing	NURF complex	An ISWI complex that contains an ATPase subunit of the ISWI family (SNF2L in mammals), a NURF301 homolog (BPTF in humans), and additional subunits, though the composition of these additional subunits varies slightly with species. NURF is involved in regulation of transcription from TRNA polymerase II promoters.	tmpzr1t_l9r_go_relaxed.owl	nucleosome remodeling factor complex													cellular_component											owl:Class	
GO:0052088	biolink:NamedThing	symbiont defense to host-produced jasmonic acid	Any process in which a symbiont modulates the frequency, rate or extent of the jasmonic acid-mediated defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	activation by symbiont of defense-related host jasmonic acid-mediated signal transduction pathway|modulation by organism of host JA-mediated defense response|stimulation by symbiont of defense-related host jasmonic acid-mediated signal transduction pathway|induction by organism of defense-related host jasmonic acid-mediated signal transduction pathway|positive regulation by symbiont of defense-related host jasmonic acid-mediated signal transduction pathway|suppression by organism of host JA-mediated defense response|induction by symbiont of defense-related host jasmonic acid-mediated signal transduction pathway|upregulation by symbiont of defense-related host jasmonic acid-mediated signal transduction pathway|induction by organism of defense-related host SA-mediated signal transduction pathway|positive regulation by organism of defense-related host SA-mediated signal transduction pathway|modulation by organism of defense-related jasmonic acid-mediated signal transduction pathway in other organism involved in symbiotic interaction|negative regulation by symbiont of host jasmonic acid-mediated defense response|up-regulation by symbiont of defense-related host jasmonic acid-mediated signal transduction pathway|positive regulation by organism of defense-related jasmonic acid-mediated signal transduction pathway in other organism involved in symbiotic interaction|modulation by organism of jasmonic acid-mediated defense response of other organism involved in symbiotic interaction|suppression by symbiont of host jasmonic acid-mediated defense response|up regulation by symbiont of defense-related host jasmonic acid-mediated signal transduction pathway|negative regulation by organism of jasmonic acid-mediated defense response of other organism involved in symbiotic interaction|activation by organism of defense-related host jasmonic acid-mediated signal transduction pathway|modulation by symbiont of defense-related host jasmonic acid-mediated signal transduction pathway|down-regulation by symbiont of host jasmonic acid-mediated defense response|upregulation by organism of defense-related host jasmonic acid-mediated signal transduction pathway|activation by organism of defense-related host SA-mediated signal transduction pathway|negative regulation by symbiont of defense-related host jasmonic acid-mediated signal transduction pathway|upregulation by organism of defense-related host SA-mediated signal transduction pathway|negative regulation by organism of defense-related jasmonic acid-mediated signal transduction pathway in other organism involved in symbiotic interaction|down regulation by symbiont of host jasmonic acid-mediated defense response|downregulation by symbiont of host jasmonic acid-mediated defense response|inhibition by symbiont of host jasmonic acid-mediated defense response	https://github.com/geneontology/go-ontology/issues/18798										GO:0052082|GO:0052069|GO:0052283|GO:0052271|GO:0052267|GO:0052068|GO:0052443|GO:0052266|GO:0052073		biological_process											owl:Class	
GO:0031895	biolink:NamedThing	V1B vasopressin receptor binding	Binding to a V1B vasopressin receptor.	tmpzr1t_l9r_go_relaxed.owl	V1B vasopressin receptor ligand													molecular_function											owl:Class	
GO:1904327	biolink:NamedThing	protein localization to cytosolic proteasome complex	A process in which a protein is transported to, or maintained in, a location within a cytosolic proteasome complex.	tmpzr1t_l9r_go_relaxed.owl	protein localisation in cytosolic proteasome complex|protein localization in cytosolic proteasome complex|protein localisation to cytosolic proteasome complex							bf	2015-06-11T09:29:53Z					biological_process											owl:Class	
GO:0045641	biolink:NamedThing	negative regulation of basophil differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of basophil differentiation.	tmpzr1t_l9r_go_relaxed.owl	downregulation of basophil differentiation|down regulation of basophil differentiation|down-regulation of basophil differentiation|inhibition of basophil differentiation													biological_process											owl:Class	
GO:0102903	biolink:NamedThing	gamma-terpinene synthase activity	Catalysis of the reaction: geranyl diphosphate = gamma-terpinene + diphosphoric acid.	tmpzr1t_l9r_go_relaxed.owl					RHEA:32559|MetaCyc:RXN-8547|EC:4.2.3.114									molecular_function											owl:Class	
GO:0097558	biolink:NamedThing	left ventral flagellum	A cilium (also called flagellum) found in Giardia species (trophozoite stage). It is nucleated by the left ventral basal body and exits the cell body proximally and dorsal to the ventral disc.	tmpzr1t_l9r_go_relaxed.owl	left ventral cilium					Note that we deem cilium and microtubule-based flagellum to be equivalent; the primary term name reflects frequency of use. Also note that, due to the asymmetric nature of the Giardia trophozoite, this term is defined spatially as the trophozoite is viewed from the dorsal side, with the two nuclei dorsal to the ventral disc, and the ventral disc toward the anterior.		pr	2014-02-05T13:26:51Z					cellular_component											owl:Class	
GO:2001064	biolink:NamedThing	cellooligosaccharide binding	Binding to cellooligosaccharide.	tmpzr1t_l9r_go_relaxed.owl								jl	2011-09-14T10:32:19Z					molecular_function											owl:Class	
GO:1905879	biolink:NamedThing	regulation of oogenesis	Any process that modulates the frequency, rate or extent of oogenesis.	tmpzr1t_l9r_go_relaxed.owl	regulation of ovum development							hbye	2017-01-31T09:31:05Z					biological_process											owl:Class	
GO:0051343	biolink:NamedThing	positive regulation of cyclic-nucleotide phosphodiesterase activity	Any process that activates or increases the frequency, rate or extent of cyclic nucleotide phosphodiesterase activity, the catalysis of the reaction: nucleotide 3',5'-cyclic phosphate + H2O = nucleotide 5'-phosphate.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of cAMP phosphodiesterase activity|3',5'-cyclic-AMP phosphodiesterase activator|positive regulation of cyclic nucleotide phosphodiesterase activity|stimulation of cyclic nucleotide phosphodiesterase activity|positive regulation of 3',5'-cyclic-AMP phosphodiesterase activity|up regulation of cyclic nucleotide phosphodiesterase activity|phosphodiesterase activator|activation of cyclic nucleotide phosphodiesterase activity|cAMP phosphodiesterase activator|up-regulation of cyclic nucleotide phosphodiesterase activity|3',5' cyclic nucleotide phosphodiesterase activator|positive regulation of 3',5' cyclic nucleotide phosphodiesterase activity|positive regulation of cGMP phosphodiesterase activity|upregulation of cyclic nucleotide phosphodiesterase activity													biological_process											owl:Class	
GO:0003294	biolink:NamedThing	atrial ventricular junction remodeling	The reorganization or renovation of heart tissue that contributes to the maturation of the connection between an atrium and a ventricle.	tmpzr1t_l9r_go_relaxed.owl	atrioventricular junction remodeling|atrio-ventricular junction remodeling							dph	2009-10-22T08:35:36Z					biological_process											owl:Class	
GO:0090521	biolink:NamedThing	glomerular visceral epithelial cell migration	The orderly movement of a podocyte from one site to another, often during the development of a multicellular organism or multicellular structure. A podocyte is a specialized kidney epithelial cell.	tmpzr1t_l9r_go_relaxed.owl	podocyte cell migration							tb	2013-01-08T11:08:57Z					biological_process											owl:Class	
GO:2000476	biolink:NamedThing	positive regulation of opioid receptor signaling pathway	Any process that activates or increases the frequency, rate or extent of opioid receptor signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of opioid receptor signalling pathway							bf	2011-03-09T09:41:35Z					biological_process											owl:Class	
GO:0018030	biolink:NamedThing	peptidyl-lysine N6-myristoyltransferase activity	Catalysis of the transfer of a myristoyl group to the N6 nitrogen atom on a lysine residue of a peptide or protein molecule.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0047323	biolink:NamedThing	[3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)] kinase activity	Catalysis of the reaction: ATP + 3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring) = ADP + 3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring) phosphate.	tmpzr1t_l9r_go_relaxed.owl	[3-methyl-2-oxobutanoate dehydrogenase (lipoamide)] kinase activity|branched-chain oxo acid dehydrogenase kinase (phosphorylating) activity|ATP:3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring) phosphotransferase activity|branched-chain keto acid dehydrogenase kinase activity|3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring) kinase activity|BCODH kinase activity|STK2|BCK|branched-chain alpha-ketoacid dehydrogenase kinase activity|branched-chain 2-oxo acid dehydrogenase kinase activity|BCKD kinase activity				RHEA:17301|Reactome:R-HSA-5693148|EC:2.7.11.4|MetaCyc:2.7.11.4-RXN									molecular_function											owl:Class	
GO:1903714	biolink:NamedThing	isoleucine transmembrane transport	The directed movement of isoleucine across a membrane.	tmpzr1t_l9r_go_relaxed.owl								vw	2014-12-06T08:19:05Z					biological_process											owl:Class	
GO:0040038	biolink:NamedThing	polar body extrusion after meiotic divisions	The cell cycle process in which two small cells are generated, as byproducts destined to degenerate, as a result of the first and second meiotic divisions of a primary oocyte during its development to a mature ovum. One polar body is formed in the first division of meiosis and the other in the second division; at each division, the cytoplasm divides unequally, so that the polar body is of much smaller size than the developing oocyte. At the second division in which a polar body is formed, the polar body and the developing oocyte each contain a haploid set of chromosomes.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0019429	biolink:NamedThing	fluorene catabolic process	The chemical reactions and pathways resulting in the breakdown of fluorene, a tricyclic polycyclic aromatic hydrocarbon containing a five-membered ring. It is a major component of fossil fuels and their derivatives and is also a by-product of coal-conversion and energy-related industries. It is commonly found in vehicle exhaust emissions, crude oils, motor oils, coal and oil combustion products, waste incineration, and industrial effluents.	tmpzr1t_l9r_go_relaxed.owl	fluorene breakdown|fluorene degradation|fluorene metabolism|fluorene metabolic process|fluorene catabolism				UM-BBD_pathwayID:flu|MetaCyc:FLUORENE-DEG-9-ONE-PWY							GO:0018917		biological_process											owl:Class	
GO:1902147	biolink:NamedThing	regulation of response to cytokinesis checkpoint signaling	Any process that modulates the frequency, rate or extent of response to cytokinesis checkpoint signaling.	tmpzr1t_l9r_go_relaxed.owl	regulation of cytokinesis checkpoint effector process|regulation of response to signal involved in cytokinesis checkpoint							jl	2013-05-21T15:43:53Z			GO:1902149		biological_process											owl:Class	
GO:0102218	biolink:NamedThing	starch, H2O dikinase activity	Catalysis of the reaction: n ATP + n H2O + starch = n AMP + n hydrogenphosphate + a 6-phosphogluco-amylopectin.	tmpzr1t_l9r_go_relaxed.owl					EC:2.7.9.4|MetaCyc:RXN-12203									molecular_function											owl:Class	
GO:0050521	biolink:NamedThing	alpha-glucan, water dikinase activity	Catalysis of the reaction: ATP + alpha-glucan + H2O = AMP + phospho-alpha-glucan + phosphate.	tmpzr1t_l9r_go_relaxed.owl	ATP:alpha-glucan, water phosphotransferase activity|starch-related R1 protein activity|GWD|a-glucan, water dikinase activity|alpha-glucan,water dikinase activity				MetaCyc:2.7.9.4-RXN|EC:2.7.9.4|RHEA:11668									molecular_function											owl:Class	
GO:0042561	biolink:NamedThing	alpha-amyrin synthase activity	Catalysis of the reaction: (S)-2,3-epoxysqualene = alpha-amyrin. This reaction is a cyclization and rearrangement of (S)-2,3-epoxysqualene (2,3-oxidosqualene) into alpha-amyrin.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-8434									molecular_function											owl:Class	
GO:0045792	biolink:NamedThing	negative regulation of cell size	Any process that reduces cell size.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of cell size|down regulation of cell size|inhibition of cell size|downregulation of cell size													biological_process											owl:Class	
GO:0007402	biolink:NamedThing	ganglion mother cell fate determination	The cell fate determination process in which a cell becomes capable of differentiating autonomously into a ganglion mother cell regardless of its environment; upon determination, the cell fate cannot be reversed.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0019797	biolink:NamedThing	procollagen-proline 3-dioxygenase activity	Catalysis of the reaction: procollagen L-proline + 2-oxoglutarate + O2 = procollagen trans-3-hydroxy-L-proline + succinate + CO2.	tmpzr1t_l9r_go_relaxed.owl	protocollagen proline 3-hydroxylase activity|prolyl 3-hydroxylase activity|prolyl-4-hydroxyprolyl-glycyl-peptide, 2-oxoglutarate: oxygen oxidoreductase, 3-hydroxylating activity|procollagen-proline,2-oxoglutarate 3-dioxygenase activity|procollagen-L-proline,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating) activity|proline,2-oxoglutarate 3-dioxygenase activity				MetaCyc:PROCOLLAGEN-PROLINE-3-DIOXYGENASE-RXN|Reactome:R-HSA-1980233|EC:1.14.11.7|KEGG_REACTION:R03218|RHEA:22872									molecular_function											owl:Class	
GO:1903903	biolink:NamedThing	regulation of establishment of T cell polarity	Any process that modulates the frequency, rate or extent of establishment of T cell polarity.	tmpzr1t_l9r_go_relaxed.owl	regulation of T cell polarization|regulation of establishment of T lymphocyte polarity|regulation of establishment of T-lymphocyte polarity|regulation of T lymphocyte polarization|regulation of T-cell polarization|regulation of establishment of T-cell polarity							als	2015-02-09T10:50:21Z					biological_process											owl:Class	
GO:1905447	biolink:NamedThing	negative regulation of mitochondrial ATP synthesis coupled electron transport	Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrial ATP synthesis coupled electron transport.	tmpzr1t_l9r_go_relaxed.owl	down regulation of mitochondrial ATP synthesis coupled electron transport|inhibition of mitochondrial ATP synthesis coupled electron transport|downregulation of mitochondrial ATP synthesis coupled electron transport|down-regulation of mitochondrial ATP synthesis coupled electron transport							dph	2016-09-15T18:58:06Z					biological_process											owl:Class	
GO:0003277	biolink:NamedThing	apoptotic process involved in endocardial cushion morphogenesis	Any apoptotic process that contributes to the shaping of an endocardial cushion. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves.	tmpzr1t_l9r_go_relaxed.owl	apoptosis involved in endocardial cushion morphogenesis							dph	2009-10-20T09:37:03Z					biological_process											owl:Class	
GO:0007488	biolink:NamedThing	histoblast morphogenesis	The process in which the anatomical structures derived from the histoblast disc are generated and organized. This includes the transformation of histoblast cells into adult structures during pupal metamorphosis. Histoblast cells are cells founded in the embryo that are the progenitors to the adult abdomen.	tmpzr1t_l9r_go_relaxed.owl	histoblast metamorphosis													biological_process											owl:Class	
GO:0051400	biolink:NamedThing	BH domain binding	Binding to a Bcl-2 homology (BH) protein domain. Bcl-2-related proteins share homology in one to four conserved regions designated the Bcl-2 homology (BH) domains BH1, BH2, BH3 and BH4. These domains contribute at multiple levels to the function of these proteins in cell death and survival. Anti-apoptotic members of the Bcl-2 family have four BH domains (BH1-BH4). Pro-apoptotic members have fewer BH domains.	tmpzr1t_l9r_go_relaxed.owl	Bcl-2 homology domain binding													molecular_function											owl:Class	
GO:0051369	biolink:NamedThing	peptidyl-threonine decanoylation	The decanoylation of peptidyl-threonine to form peptidyl-O3-decanoyl-L-threonine, typical of the protein ghrelin.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0387									biological_process											owl:Class	
GO:0140690	biolink:NamedThing	dihydropyrimidine dehydrogenase (NAD+) complex	A heteromultimeric complex capable of dihydropyrimidine dehydrogenase (NAD+); in E. coli, composed of PreA and PreT.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/21891			MetaCyc:CPLX0-7788			pg	2021-08-04T05:52:44Z					cellular_component											owl:Class	
GO:0072079	biolink:NamedThing	nephron tubule formation	The developmental process pertaining to the initial formation of a nephron tubule from unspecified parts. A nephron tubule is an epithelial tube that is part of the nephron, the functional part of the kidney.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-02-01T02:29:26Z					biological_process											owl:Class	
GO:1902657	biolink:NamedThing	protein localization to prospore membrane	A process in which a protein is transported to, or maintained in, a location within a prospore membrane.	tmpzr1t_l9r_go_relaxed.owl	protein targeting to forespore membrane|protein localization in prospore membrane|establishment of protein localization in prospore membrane|establishment of protein localisation in prospore membrane|protein targeting to FSM|protein targeting to prospore membrane|establishment of protein localization to prospore membrane|protein targeting to ascospore-type prospore membrane|protein-prospore membrane targeting|establishment of protein localisation to prospore membrane|protein localisation to prospore membrane|protein localisation in prospore membrane							dph	2011-11-16T11:28:26Z			GO:1902658|GO:0072693		biological_process											owl:Class	
GO:0061455	biolink:NamedThing	integral component of muscle cell projection membrane	The component of the muscle cell projection membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.	tmpzr1t_l9r_go_relaxed.owl	integral to muscle cell projection membrane							dph	2012-07-27T02:38:01Z					cellular_component											owl:Class	
GO:0110164	biolink:NamedThing	positive regulation of mitotic spindle elongation (spindle phase three)	Any process that activates or increases the frequency, rate or extent of the cell cycle process in which the distance is lengthened between poles of the mitotic spindle during mitotic prophase (spindle phase three).	tmpzr1t_l9r_go_relaxed.owl								kmv	2019-08-12T15:32:20Z					biological_process											owl:Class	
GO:0061614	biolink:NamedThing	pri-miRNA transcription by RNA polymerase II	The cellular synthesis of primary microRNA (pri-miRNA) transcripts from a DNA template by RNA polymerase II, originating at an RNA polymerase II promoter. pri-miRNA transcripts are subsequently processed to produce the ~22nt miRNAs that function in gene regulation.	tmpzr1t_l9r_go_relaxed.owl	pri-miRNA transcription from RNA polymerase II promoter	https://github.com/geneontology/go-ontology/issues/14854						dph	2014-04-08T08:42:54Z					biological_process											owl:Class	
GO:0046236	biolink:NamedThing	mandelate biosynthetic process	The chemical reactions and pathways resulting in the formation of mandelate, the anion of mandelic acid. Mandelic acid (alpha-hydroxybenzeneacetic acid) is an 8-carbon alpha-hydroxy acid (AHA) that is used in organic chemistry and as a urinary antiseptic.	tmpzr1t_l9r_go_relaxed.owl	mandelate anabolism|mandelate biosynthesis|mandelate formation|mandelate synthesis													biological_process											owl:Class	
GO:0018924	biolink:NamedThing	mandelate metabolic process	The chemical reactions and pathways involving mandelate, the anion of mandelic acid. Mandelic acid (alpha-hydroxybenzeneacetic acid) is an 8-carbon alpha-hydroxy acid (AHA) that is used in organic chemistry and as a urinary antiseptic.	tmpzr1t_l9r_go_relaxed.owl	mandelic acid metabolic process|mandelic acid metabolism|mandelate metabolism				UM-BBD_pathwayID:mca									biological_process											owl:Class	
GO:0033952	biolink:NamedThing	iota-carrageenase activity	Catalysis of the endohydrolysis of 1,4-beta-D-linkages between D-galactose 4-sulfate and 3,6-anhydro-D-galactose-2-sulfate in iota-carrageenans.	tmpzr1t_l9r_go_relaxed.owl	iota-carrageenan 4-beta-D-glycanohydrolase (configuration-inverting) activity				EC:3.2.1.157|MetaCyc:3.2.1.157-RXN									molecular_function											owl:Class	
GO:1901075	biolink:NamedThing	negative regulation of engulfment of apoptotic cell	Any process that stops, prevents or reduces the frequency, rate or extent of engulfment of apoptotic cell.	tmpzr1t_l9r_go_relaxed.owl	down regulation of engulfment of cell corpse|inhibition of engulfment of apoptotic cell|down-regulation of engulfment of apoptotic cell corpse|down regulation of engulfment of apoptotic cell|inhibition of engulfment of apoptotic cell corpse|downregulation of engulfment of apoptotic cell|downregulation of engulfment of apoptotic cell corpse|down-regulation of engulfment of cell corpse|inhibition of engulfment of cell corpse|down-regulation of engulfment of apoptotic cell|negative regulation of engulfment of cell corpse|downregulation of engulfment of cell corpse|negative regulation of engulfment of apoptotic cell corpse|down regulation of engulfment of apoptotic cell corpse							kmv	2012-07-02T07:32:43Z					biological_process											owl:Class	
GO:0016012	biolink:NamedThing	sarcoglycan complex	A protein complex formed of four sarcoglycans plus sarcospan; there are six known sarcoglycans: alpha-, beta-, gamma-, delta-, epsilon- and zeta-sarcoglycan; all are N-glycosylated single-pass transmembrane proteins. The sarcoglycan-sarcospan complex is a subcomplex of the dystrophin glycoprotein complex, and is fixed to the dystrophin axis by a lateral association with the dystroglycan complex.	tmpzr1t_l9r_go_relaxed.owl	sarcoglycan-sarcospan complex													cellular_component											owl:Class	
GO:2000299	biolink:NamedThing	negative regulation of Rho-dependent protein serine/threonine kinase activity	Any process that stops, prevents or reduces the frequency, rate or extent of Rho-dependent protein serine/threonine kinase activity.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of Rho-associated protein kinase activity|negative regulation of ROCK kinase activity							mah	2010-12-23T11:44:57Z					biological_process											owl:Class	
GO:0120042	biolink:NamedThing	negative regulation of macrophage proliferation	Any process that stops, prevents, or reduces the frequency, rate or extent of macrophage proliferation.	tmpzr1t_l9r_go_relaxed.owl								krc	2017-05-10T20:51:40Z					biological_process											owl:Class	
GO:2000647	biolink:NamedThing	negative regulation of stem cell proliferation	Any process that stops, prevents or reduces the frequency, rate or extent of stem cell proliferation.	tmpzr1t_l9r_go_relaxed.owl								dph	2011-04-27T01:04:22Z					biological_process											owl:Class	
GO:0071450	biolink:NamedThing	cellular response to oxygen radical	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxygen radical stimulus. An oxygen radical is any oxygen species that carries a free electron; examples include hydroxyl radicals and the superoxide anion.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-12-16T04:38:52Z					biological_process											owl:Class	
GO:0006249	biolink:NamedThing	dCMP catabolic process	The chemical reactions and pathways resulting in the breakdown of dCMP, deoxycytidine monophosphate.	tmpzr1t_l9r_go_relaxed.owl	dCMP breakdown|dCMP catabolism|dCMP degradation													biological_process											owl:Class	
GO:0046063	biolink:NamedThing	dCMP metabolic process	The chemical reactions and pathways involving dCMP, deoxycytidine monophosphate.	tmpzr1t_l9r_go_relaxed.owl	dCMP metabolism													biological_process											owl:Class	
GO:1904576	biolink:NamedThing	response to tunicamycin	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tunicamycin stimulus.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-08-19T18:01:52Z					biological_process											owl:Class	
GO:0070563	biolink:NamedThing	negative regulation of vitamin D receptor signaling pathway	Any process that stops, prevents, or reduces the frequency, rate or extent of the vitamin D receptor signaling pathway activity.	tmpzr1t_l9r_go_relaxed.owl	downregulation of vitamin D receptor signaling pathway|down regulation of vitamin D receptor signaling pathway|inhibition of vitamin D receptor signaling pathway|negative regulation of VDR signalling pathway|negative regulation vitamin D receptor signalling pathway|down-regulation of vitamin D receptor signaling pathway|negative regulation of VDR signaling pathway							mah	2009-04-14T01:59:21Z					biological_process											owl:Class	
GO:1905954	biolink:NamedThing	positive regulation of lipid localization	Any process that activates or increases the frequency, rate or extent of lipid localization.	tmpzr1t_l9r_go_relaxed.owl	activation of lipid localisation|up-regulation of lipid localization|up regulation of lipid localization|up regulation of lipid localisation|upregulation of lipid localization|activation of lipid localization|positive regulation of lipid localisation|upregulation of lipid localisation|up-regulation of lipid localisation							rz	2017-02-21T12:12:49Z					biological_process											owl:Class	
GO:0004550	biolink:NamedThing	nucleoside diphosphate kinase activity	Catalysis of the reaction: ATP + nucleoside diphosphate = ADP + nucleoside triphosphate.	tmpzr1t_l9r_go_relaxed.owl	nucleoside diphosphate (UDP) kinase activity|ATP:nucleoside-diphosphate phosphotransferase activity|nucleoside-diphosphate kinase activity|UDP kinase activity|nucleoside 5'-diphosphate kinase activity|NDK activity|uridine diphosphate kinase activity|nucleoside 5'-diphosphate phosphotransferase activity|nucleotide phosphate kinase activity|nucleoside diphosphokinase activity				Reactome:R-HSA-2162096|Reactome:R-HSA-482619|Reactome:R-HSA-482804|Reactome:R-HSA-482812|EC:2.7.4.6|MetaCyc:NUCLEOSIDE-DIP-KIN-RXN|Reactome:R-HSA-6806877|Reactome:R-HSA-482621									molecular_function											owl:Class	
GO:0032084	biolink:NamedThing	regulation of type I site-specific deoxyribonuclease activity	Any process that modulates the frequency, rate or extent of a type I restriction endodeoxyribonuclease activity.	tmpzr1t_l9r_go_relaxed.owl	type I restriction enzyme regulator|type I restriction endodeoxyribonuclease regulator|regulation of type I restriction endodeoxyribonuclease activity													biological_process											owl:Class	
GO:0043112	biolink:NamedThing	receptor metabolic process	The chemical reactions and pathways involving a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.	tmpzr1t_l9r_go_relaxed.owl	receptor metabolism													biological_process											owl:Class	
GO:0072170	biolink:NamedThing	metanephric tubule development	The progression of a metanephric tubule over time, from its initial formation to the mature structure. A metanephric tubule is an epithelial tube that is part of the metanephros.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-02-26T01:58:18Z					biological_process											owl:Class	
GO:0006653	biolink:NamedThing	1,2-diacyl-sn-glycero-3-phosphocholine metabolic process	The chemical reactions and pathways involving any 1,2-diacyl-sn-glycero-3-phosphocholine, the compounds most commonly designated lecithin.	tmpzr1t_l9r_go_relaxed.owl	1,2-diacyl-sn-glycero-3-phosphocholine metabolism|lecithin metabolic process													biological_process											owl:Class	
GO:0016108	biolink:NamedThing	tetraterpenoid metabolic process	The chemical reactions and pathways involving tetraterpenoid compounds, terpenoids with eight isoprene units.	tmpzr1t_l9r_go_relaxed.owl	tetraterpenoid metabolism|tetraterpene metabolism|tetraterpene metabolic process													biological_process											owl:Class	
GO:1990634	biolink:NamedThing	protein phosphatase 5 binding	Binding to protein phosphatase 5.	tmpzr1t_l9r_go_relaxed.owl	protein phosphatase T binding							sl	2015-02-10T21:30:41Z					molecular_function											owl:Class	
GO:0019903	biolink:NamedThing	protein phosphatase binding	Binding to a protein phosphatase.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0051958	biolink:NamedThing	methotrexate transport	The directed movement of methotrexate, 4-amino-10-methylformic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Methotrexate is a folic acid analogue and a potent competitive inhibitor of dihydrofolate reductase.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0033915	biolink:NamedThing	mannan 1,2-(1,3)-alpha-mannosidase activity	Catalysis of the hydrolysis of (1->2) and (1->3) linkages in mannan, releasing mannose.	tmpzr1t_l9r_go_relaxed.owl	exo-1,2-1,3-alpha-mannosidase activity|1,2-1,3-alpha-D-mannan mannohydrolase activity				MetaCyc:3.2.1.77-RXN|EC:3.2.1.77									molecular_function											owl:Class	
GO:0060030	biolink:NamedThing	dorsal convergence	The directed migration of individual cells and small groups of cells toward the dorsal midline during gastrulation. This process does not require cell rearrangement.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1900153	biolink:NamedThing	positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	Any process that activates or increases the frequency, rate or extent of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay.	tmpzr1t_l9r_go_relaxed.owl	activation of mRNA catabolism, deadenylylation-dependent|upregulation of mRNA catabolism, deadenylylation-dependent|activation of mRNA breakdown, deadenylation-dependent decay|positive regulation of mRNA catabolism, deadenylation-dependent|up regulation of mRNA catabolic process, deadenylylation-dependent|upregulation of mRNA catabolic process, deadenylation-dependent|up-regulation of mRNA degradation, deadenylation-dependent decay|activation of mRNA catabolic process, deadenylation-dependent|positive regulation of deadenylation-dependent mRNA decay|up-regulation of mRNA catabolism, deadenylylation-dependent|up regulation of mRNA catabolism, deadenylation-dependent|activation of deadenylation-dependent mRNA decay|up-regulation of nuclear mRNA catabolic process, deadenylation-dependent decay|activation of mRNA catabolism, deadenylation-dependent|up regulation of mRNA breakdown, deadenylation-dependent decay|up regulation of nuclear mRNA catabolic process, deadenylation-dependent decay|upregulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay|upregulation of mRNA breakdown, deadenylation-dependent decay|positive regulation of mRNA degradation, deadenylation-dependent decay|activation of nuclear mRNA catabolic process, deadenylation-dependent decay|positive regulation of mRNA catabolic process, deadenylation-dependent|upregulation of mRNA catabolic process, deadenylylation-dependent|positive regulation of mRNA breakdown, deadenylation-dependent decay|up-regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay|activation of mRNA catabolic process, deadenylylation-dependent|up regulation of mRNA degradation, deadenylation-dependent decay|up regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay|upregulation of mRNA catabolism, deadenylation-dependent|up-regulation of mRNA catabolic process, deadenylylation-dependent|activation of mRNA degradation, deadenylation-dependent decay|up regulation of deadenylation-dependent mRNA decay|positive regulation of nuclear mRNA catabolic process, deadenylation-dependent decay|up regulation of mRNA catabolic process, deadenylation-dependent|up regulation of mRNA catabolism, deadenylylation-dependent|up-regulation of mRNA breakdown, deadenylation-dependent decay|positive regulation of mRNA catabolism, deadenylylation-dependent|activation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay|positive regulation of mRNA catabolic process, deadenylylation-dependent|up-regulation of mRNA catabolic process, deadenylation-dependent|upregulation of deadenylation-dependent mRNA decay|upregulation of mRNA degradation, deadenylation-dependent decay|upregulation of nuclear mRNA catabolic process, deadenylation-dependent decay|up-regulation of deadenylation-dependent mRNA decay|up-regulation of mRNA catabolism, deadenylation-dependent							bf	2012-03-07T09:14:52Z					biological_process											owl:Class	
GO:0031827	biolink:NamedThing	type 2B serotonin receptor binding	Binding to a type 2B serotonin receptor.	tmpzr1t_l9r_go_relaxed.owl	type 2B serotonin receptor ligand|5-hydroxytryptamine 2B receptor binding													molecular_function											owl:Class	
GO:0034741	biolink:NamedThing	APC-tubulin-IQGAP1 complex	A protein complex that contains the tumor suppressor protein adenomatous polyposis coli (APC), alpha-tubulin, gamma-tubulin, and the Rac1 and Cdc42 effector IQGAP1; may play a role in cytoskeleton organization.	tmpzr1t_l9r_go_relaxed.owl	60S APC complex					Note that the gene/protein name 'APC' should not be confused with the abbreviation for 'anaphase promoting complex'.								cellular_component											owl:Class	
GO:0150099	biolink:NamedThing	neuron-glial cell signaling	Cell-cell signaling that mediates the transfer of information from a neuron to a glial cell. This signalling has been shown to be mediated by various molecules released by different types of neurons, e.g. glutamate, gamma-amino butyric acid (GABA), noradrenaline, acetylcholine, dopamine and adenosine.	tmpzr1t_l9r_go_relaxed.owl	neurone-glial cell signaling|neuron-glia signaling|neurone-glia signaling|neurone-glial cell signalling|neurone-glia signalling|neuron-glia signalling|neuron-glial cell signalling							bc	2018-12-17T12:30:12Z					biological_process											owl:Class	
GO:1904686	biolink:NamedThing	regulation of mitotic spindle disassembly	Any process that modulates the frequency, rate or extent of mitotic spindle disassembly.	tmpzr1t_l9r_go_relaxed.owl	regulation of spindle breakdown during mitosis|regulation of mitotic spindle degradation|regulation of mitotic spindle breakdown|regulation of spindle degradation during mitosis|regulation of mitotic spindle catabolism|regulation of spindle disassembly during mitosis							al	2015-09-24T14:20:07Z					biological_process											owl:Class	
GO:0004471	biolink:NamedThing	malate dehydrogenase (decarboxylating) (NAD+) activity	Catalysis of the reaction: (S)-malate + NAD+ = pyruvate + CO2 + NADH + H+.	tmpzr1t_l9r_go_relaxed.owl	NAD-linked malic enzyme|(S)-malate:NAD+ oxidoreductase (oxaloacetate-decarboxylating)|NAD-malic enzyme activity|malate dehydrogenase (oxaloacetate-decarboxylating) activity|(S)-malate:NAD+ oxidoreductase (decarboxylating)|malate dehydrogenase (decarboxylating) activity|NAD-specific malic enzyme|'malic' enzyme				MetaCyc:MALIC-NAD-RXN|EC:1.1.1.38|RHEA:12653|EC:1.1.1.39|Reactome:R-HSA-9012268|MetaCyc:1.1.1.39-RXN|KEGG_REACTION:R00214	For decarboxylation of oxaloacetate (the second substrate listed in EC:1.1.1.38), see 'oxaloacetate decarboxylase activity ; GO:0008948'.						GO:0016619|GO:0004472		molecular_function											owl:Class	
GO:0061985	biolink:NamedThing	carbon catabolite repression	A process in which the presence of one carbon source leads to the modulation of the frequency, rate, or extent of the metabolism of other carbon sources.	tmpzr1t_l9r_go_relaxed.owl								dph	2018-02-15T16:49:48Z					biological_process											owl:Class	
GO:1905053	biolink:NamedThing	positive regulation of base-excision repair	Any process that activates or increases the frequency, rate or extent of base-excision repair.	tmpzr1t_l9r_go_relaxed.owl	upregulation of BER|upregulation of base-excision repair|up regulation of base-excision repair|up regulation of BER|activation of BER|up-regulation of BER|positive regulation of BER|up-regulation of base-excision repair|activation of base-excision repair							ah	2016-03-16T10:52:18Z					biological_process											owl:Class	
GO:0036426	biolink:NamedThing	ditrans, polycis-undecaprenyl-phosphate mannosyltransferase activity	Catalysis of the reaction: ditrans,octacis-undecaprenyl phosphate + GDP-alpha-D-mannose = D-mannosyl undecaprenyl phosphate+ GDP.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:2.4.1.54-RXN|KEGG_REACTION:R07257			bf	2013-09-16T13:21:01Z					molecular_function											owl:Class	
GO:0098888	biolink:NamedThing	extrinsic component of presynaptic membrane	The component of the presynaptic membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.	tmpzr1t_l9r_go_relaxed.owl	extrinsic component of presynaptic plasma membrane													cellular_component											owl:Class	
GO:0018501	biolink:NamedThing	cis-chlorobenzene dihydrodiol dehydrogenase activity	Catalysis of the conversion of a di- or tetrachlorinated dienol to the corresponding catechol.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_enzymeID:e0411									molecular_function											owl:Class	
GO:1902120	biolink:NamedThing	negative regulation of meiotic spindle elongation	Any process that stops, prevents or reduces the frequency, rate or extent of meiotic spindle elongation.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of spindle elongation during meiosis|down regulation of meiotic spindle elongation|downregulation of meiotic spindle elongation|inhibition of meiotic spindle elongation|down regulation of spindle elongation during meiosis|down-regulation of meiotic spindle elongation|negative regulation of spindle elongation during meiosis|inhibition of spindle elongation during meiosis|downregulation of spindle elongation during meiosis							al	2013-05-15T15:15:53Z					biological_process											owl:Class	
GO:0120205	biolink:NamedThing	photoreceptor proximal connecting cilium	The proximal region of the photoreceptor connecting cilium is similar to the transition zone of unspecialized primary cilia and houses several major transition zone complexes, including NPHP, MKS, and RPGR.	tmpzr1t_l9r_go_relaxed.owl	PCC|photoreceptor PCC							krc	2019-05-10T22:47:08Z					cellular_component											owl:Class	
GO:2000164	biolink:NamedThing	negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis	Any process that stops, prevents, or reduces the frequency, rate or extent of planar cell polarity pathway involved in outflow tract morphogenesis.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-10-05T01:06:15Z					biological_process											owl:Class	
GO:2000163	biolink:NamedThing	regulation of planar cell polarity pathway involved in outflow tract morphogenesis	Any process that modulates the frequency, rate or extent of planar cell polarity pathway involved in outflow tract morphogenesis.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-10-05T01:06:13Z					biological_process											owl:Class	
GO:0018953	biolink:NamedThing	p-cymene metabolic process	The chemical reactions and pathways involving p-cymene, 1-methyl-4-isopropylbenzene, one of the alkyl-substituted aromatic hydrocarbons found in volatile oils from over 100 plants.	tmpzr1t_l9r_go_relaxed.owl	p-cymene metabolism				UM-BBD_pathwayID:pcy									biological_process											owl:Class	
GO:0000241	biolink:NamedThing	diakinesis	The cell cycle phase which follows diplotene during prophase I of meiosis, the separation of homologous chromosomes is complete and crossing over has occurred.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Diakinesis|Wikipedia:Meiosis#Diakinesis	Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).								biological_process											owl:Class	
GO:1905745	biolink:NamedThing	negative regulation of mRNA cis splicing, via spliceosome	Any process that stops, prevents or reduces the frequency, rate or extent of mRNA cis splicing, via spliceosome.	tmpzr1t_l9r_go_relaxed.owl								vw	2016-12-07T14:01:42Z					biological_process											owl:Class	
GO:1902087	biolink:NamedThing	dimethylsulfoniopropionate catabolic process	The chemical reactions and pathways resulting in the breakdown of S,S-dimethyl-beta-propiothetin.	tmpzr1t_l9r_go_relaxed.owl	S,S-dimethyl-beta-propiothetin catabolic process|S,S-dimethyl-beta-propiothetin catabolism|S,S-dimethyl-beta-propiothetin breakdown|S,S-dimethyl-beta-propiothetin degradation							tb	2013-04-26T17:29:13Z					biological_process											owl:Class	
GO:1905173	biolink:NamedThing	eukaryotic translation initiation factor 2B complex assembly	The aggregation, arrangement and bonding together of a set of components to form an eukaryotic translation initiation factor 2B complex.	tmpzr1t_l9r_go_relaxed.owl	eukaryotic translation initiation factor 2B complex formation|eIF-2B assembly|eif2B formation|eif2B assembly|eIF-2B formation							mah	2016-05-03T11:00:21Z					biological_process											owl:Class	
GO:0045914	biolink:NamedThing	negative regulation of catecholamine metabolic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving catecholamine.	tmpzr1t_l9r_go_relaxed.owl	inhibition of catecholamine metabolic process|down regulation of catecholamine metabolic process|down-regulation of catecholamine metabolic process|downregulation of catecholamine metabolic process|negative regulation of catecholamine metabolism													biological_process											owl:Class	
GO:0039534	biolink:NamedThing	negative regulation of MDA-5 signaling pathway	Any process that stops, prevents, or reduces the frequency, rate or extent of the series of molecular signals generated as a consequence of the cytoplasmic pattern recognition receptor (PRR) MDA-5 (also known as IFIH1) binding to viral RNA.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of melanoma differentiation-associated gene 5 signaling pathway|negative regulation of MDA-5 signalling pathway|negative regulation of MDA5 signaling pathway|negative regulation of IFIH1 signaling pathway							bf	2012-01-03T11:21:20Z					biological_process											owl:Class	
GO:0039533	biolink:NamedThing	regulation of MDA-5 signaling pathway	Any process that modulates the frequency, rate or extent of the series of molecular signals generated as a consequence of the cytoplasmic pattern recognition receptor (PRR) MDA-5 (also known as IFIH1) binding to viral RNA.	tmpzr1t_l9r_go_relaxed.owl	regulation of IFIH1 signaling pathway|regulation of melanoma differentiation-associated gene 5 signaling pathway|regulation of MDA-5 signalling pathway|regulation of MDA5 signaling pathway							bf	2012-01-03T11:17:31Z					biological_process											owl:Class	
GO:0097743	biolink:NamedThing	de novo centriole assembly via blepharoplast	A de novo centriole assembly process observed in multi-ciliated sperm cells of some primitive land plants, and where centrioles are formed from a blepharoplast, ultimately giving rise to multiple cilia on the sperm surface.	tmpzr1t_l9r_go_relaxed.owl	multiciliation|multiciliogenesis							pr	2016-10-19T15:18:34Z					biological_process											owl:Class	
GO:0097742	biolink:NamedThing	de novo centriole assembly	Centriole assembly in which a centriole arises de novo, rather than by replication from an existing centriole. This process may occur via different mechanisms. Examples include the deuterosome pathway in multicilated epithelial animal cells and formation of centrioles during parthenogenesis in some insects.	tmpzr1t_l9r_go_relaxed.owl	de novo basal body amplification|multiciliation|de novo basal body biogenesis|de novo basal body generation|multiciliogenesis|de novo basal body assembly|de novo centriole amplification|de novo ciliary basal body assembly|acentriolar basal body biogenesis							pr	2016-10-19T15:13:50Z					biological_process											owl:Class	
GO:0052760	biolink:NamedThing	coenzyme F420-dependent 2,4-dinitrophenol reductase activity	Catalysis of the reaction: 2,4-dinitrophenol + H- = 2,4-dinitrophenol hydride Meisenheimer complex. Coenzyme F420 supplies the hydride (H-) in the reaction.	tmpzr1t_l9r_go_relaxed.owl	DNP reductase activity|coenzyme F420-dependent 2,4-dinitrophenol hydride transferase activity				EC:1.3.99.-|UM-BBD_reactionID:r1071			ai	2011-09-28T02:47:31Z					molecular_function											owl:Class	
GO:1901759	biolink:NamedThing	beta-L-Ara4N-lipid A metabolic process	The chemical reactions and pathways involving beta-L-Ara4N-lipid A.	tmpzr1t_l9r_go_relaxed.owl	beta-L-Ara4N-lipid A metabolism|4-amino-4-deoxy-beta-L-arabinose-lipid A metabolism|4-amino-4-deoxy-beta-L-arabinose-lipid A metabolic process							pr	2013-01-14T12:52:57Z					biological_process											owl:Class	
GO:0033671	biolink:NamedThing	negative regulation of NAD+ kinase activity	Any process that stops, prevents, or reduces the frequency, rate or extent of NAD kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to an NAD molecule.	tmpzr1t_l9r_go_relaxed.owl	downregulation of NAD+ kinase activity|inhibition of NAD+ kinase activity|down-regulation of NAD+ kinase activity|down regulation of NAD+ kinase activity|NAD+ kinase inhibitor													biological_process											owl:Class	
GO:0046282	biolink:NamedThing	cinnamic acid ester catabolic process	The chemical reactions and pathways resulting in the breakdown of ester derivatives of cinnamic acid, phenylpropenoic acid.	tmpzr1t_l9r_go_relaxed.owl	cinnamic acid ester catabolism|cinnamic acid ester degradation|cinnamic acid ester breakdown													biological_process											owl:Class	
GO:0009801	biolink:NamedThing	cinnamic acid ester metabolic process	The chemical reactions and pathways involving ester derivatives of cinnamic acid, phenylpropenoic acid.	tmpzr1t_l9r_go_relaxed.owl	cinnamic acid ester metabolism													biological_process											owl:Class	
GO:0090465	biolink:NamedThing	arginine homeostasis	Any process involved in the maintenance of an internal steady state of arginine within an organism or cell.	tmpzr1t_l9r_go_relaxed.owl								tb	2012-09-24T14:22:02Z					biological_process											owl:Class	
GO:0042286	biolink:NamedThing	glutamate-1-semialdehyde 2,1-aminomutase activity	Catalysis of the reaction: (S)-4-amino-5-oxopentanoate = 5-aminolevulinate.	tmpzr1t_l9r_go_relaxed.owl	glutamate-1-semialdehyde aminotransferase activity|(S)-4-amino-5-oxopentanoate 4,5-aminomutase activity				EC:5.4.3.8|RHEA:14265|MetaCyc:GSAAMINOTRANS-RXN|KEGG_REACTION:R02272									molecular_function											owl:Class	
GO:0061377	biolink:NamedThing	mammary gland lobule development	The progression of the mammary gland lobule over time, from its formation to the mature structure. A mammary gland lobule is a small rounded projection of the mammary gland.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-11-09T09:36:29Z					biological_process											owl:Class	
GO:0072749	biolink:NamedThing	cellular response to cytochalasin B	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytochalasin B stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2012-08-31T12:37:15Z					biological_process											owl:Class	
GO:0048194	biolink:NamedThing	Golgi vesicle budding	The evagination of the Golgi membrane, resulting in formation of a vesicle.	tmpzr1t_l9r_go_relaxed.owl	dictyosome vesicle budding|Golgi-derived vesicle budding													biological_process											owl:Class	
GO:0140351	biolink:NamedThing	glycosylceramide flippase activity	Catalysis of the movement of glycosylceramide from the exoplasmic to the cytosolic leaftlet of a membrane, using energy from the hydrolysis of ATP. Glycosylceramides are ceramides containing a functional group derived from a sugar.	tmpzr1t_l9r_go_relaxed.owl	glycoceramide flippase activity|galactocerebroside flippase activity|glucosylceramide flippase activity|glycosylceramide flippase activity (exoplasmic to cytosolic leaftlet)|galactosylceramide flippase activity							pg	2019-05-20T13:29:48Z					molecular_function											owl:Class	
GO:0030585	biolink:NamedThing	phosphoenolpyruvate carboxykinase (diphosphate) activity	Catalysis of the reaction: diphosphate + oxaloacetate = CO(2) + phosphate + phosphoenolpyruvate.	tmpzr1t_l9r_go_relaxed.owl	phosphoenolpyruvic carboxykinase (pyrophosphate)|phosphoenolpyruvic carboxykinase|PEP carboxyphosphotransferase activity|phosphoenolpyruvic carboxytransphosphorylase activity|phosphoenolpyruvate carboxyphosphotransferase activity|phosphopyruvate carboxykinase|phosphopyruvate carboxykinase (pyrophosphate)|phosphoenolpyruvate carboxylase (pyrophosphate)|phosphoenolpyruvic carboxylase (pyrophosphate)|PEPCTrP|phosphopyruvate carboxylase (pyrophosphate)|phosphoenolpyruvate carboxykinase (pyrophosphate) activity|phosphoenolpyruvate carboxytransphosphorylase activity|diphosphate:oxaloacetate carboxy-lyase (transphosphorylating)|diphosphate:oxaloacetate carboxy-lyase (transphosphorylating; phosphoenolpyruvate-forming)				MetaCyc:4.1.1.38-RXN|RHEA:22356|KEGG_REACTION:R00346|EC:4.1.1.38									molecular_function											owl:Class	
GO:0045049	biolink:NamedThing	protein insertion into ER membrane by N-terminal cleaved signal sequence	A process of protein insertion into the endoplasmic reticulum (ER) membrane in which N-terminal cleaved signal sequences direct polypeptides to the ER.	tmpzr1t_l9r_go_relaxed.owl	protein insertion into ER membrane, N-terminal cleaved signal sequence mediated|protein insertion into endoplasmic reticulum membrane by N-terminal cleaved signal sequence|N-terminal cleaved signal sequence mediated protein insertion into ER membrane|protein-endoplasmic reticulum insertion by N-terminal cleaved signal sequence|protein-ER insertion by N-terminal cleaved signal sequence													biological_process											owl:Class	
GO:0071466	biolink:NamedThing	cellular response to xenobiotic stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a xenobiotic, a compound foreign to the organism exposed to it. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical.	tmpzr1t_l9r_go_relaxed.owl	cellular response to drug	https://github.com/geneontology/go-ontology/issues/19460						mah	2009-12-18T11:38:48Z			GO:0035690		biological_process											owl:Class	
GO:0015232	biolink:NamedThing	heme transmembrane transporter activity	Enables the transfer of heme from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	heme transporter activity|haem transporter activity	https://github.com/geneontology/go-ontology/issues/19472			Reactome:R-HSA-917892|Reactome:R-HSA-917870|Reactome:R-HSA-9661408									molecular_function											owl:Class	
GO:0019248	biolink:NamedThing	D-lactate biosynthetic process from methylglyoxal via (R)-lactaldehyde	The chemical reactions and pathways resulting in the formation of D-lactate from methylglyoxal, via the intermediate (R)-lactaldehyde.	tmpzr1t_l9r_go_relaxed.owl	D-lactate formation from methylglyoxal via (R)-lactaldehyde|D-lactate synthesis from methylglyoxal via (R)-lactaldehyde|D-lactate anabolism from methylglyoxal via (R)-lactaldehyde				MetaCyc:MGLDLCTANA-PWY									biological_process											owl:Class	
GO:1903585	biolink:NamedThing	negative regulation of histone deubiquitination	Any process that stops, prevents or reduces the frequency, rate or extent of histone deubiquitination.	tmpzr1t_l9r_go_relaxed.owl	downregulation of histone deubiquitination|negative regulation of histone deubiquitinylation|inhibition of histone deubiquitinylation|inhibition of histone deubiquitination|downregulation of histone deubiquitylation|down regulation of histone deubiquitination|downregulation of histone deubiquitinylation|down-regulation of histone deubiquitinylation|down regulation of histone deubiquitylation|down-regulation of histone deubiquitylation|inhibition of histone deubiquitylation|negative regulation of histone deubiquitylation|down-regulation of histone deubiquitination|down regulation of histone deubiquitinylation							lb	2014-11-03T13:47:35Z					biological_process											owl:Class	
GO:0015430	biolink:NamedThing	ABC-type glycerol-3-phosphate transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + glycerol-3-phosphate(out) = ADP + phosphate + glycerol-3-phosphate(in).	tmpzr1t_l9r_go_relaxed.owl	glycerol-3-phosphate-transporting ATPase|ATPase-coupled glycerol-2-phosphate transmembrane transporter activity|ABC-type glycerol 3-phosphate transporter|ATP-dependent glycerol-2-phosphate transmembrane transporter activity|glycerol-phosphate porter activity|ATPase-coupled glycerol-3-phosphate transmembrane transporter activity|glycerol-2-phosphate-transporting ATPase activity|glycerol-3-phosphate ABC transporter|glycerol phosphate-importing ATPase activity	https://github.com/geneontology/go-ontology/issues/17164			EC:7.6.2.10|RHEA:21668|MetaCyc:3.6.3.20-RXN							GO:0070812|GO:0015610		molecular_function											owl:Class	
GO:0004132	biolink:NamedThing	dCMP deaminase activity	Catalysis of the reaction: dCMP + H2O = dUMP + NH3.	tmpzr1t_l9r_go_relaxed.owl	deoxycytidine-5'-monophosphate aminohydrolase activity|deoxycytidylate deaminase activity|deoxycytidine-5'-phosphate deaminase activity|deoxy-CMP-deaminase activity|deoxycytidylate aminohydrolase activity|deoxycytidine monophosphate deaminase activity|dCMP aminohydrolase activity				RHEA:22924|EC:3.5.4.12|MetaCyc:DCMP-DEAMINASE-RXN|Reactome:R-HSA-73596									molecular_function											owl:Class	
GO:1900891	biolink:NamedThing	negative regulation of pentadecane metabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of pentadecane metabolic process.	tmpzr1t_l9r_go_relaxed.owl	downregulation of pentadecane metabolic process|down-regulation of pentadecane metabolism|down-regulation of pentadecane metabolic process|inhibition of pentadecane metabolism|downregulation of pentadecane metabolism|down regulation of pentadecane metabolism|negative regulation of pentadecane metabolism|down regulation of pentadecane metabolic process|inhibition of pentadecane metabolic process							tt	2012-06-13T03:06:11Z					biological_process											owl:Class	
GO:0033593	biolink:NamedThing	BRCA2-MAGE-D1 complex	A heterodimeric protein complex formed of BRCA2 and MAGE-D1; may mediate the synergistic activities of the two proteins in regulating cell growth.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0014710	biolink:NamedThing	negative regulation of somitomeric trunk muscle development	Any process that stops, prevents, or reduces the frequency, rate or extent of somitomeric trunk muscle development. The somitomeric trunk muscle is derived from somitomeric mesoderm. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0071559	biolink:NamedThing	response to transforming growth factor beta	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a transforming growth factor beta stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to transforming growth factor beta stimulus|response to TGFbeta stimulus|response to TGF-beta stimulus							mah	2010-01-20T11:49:59Z					biological_process											owl:Class	
GO:0099126	biolink:NamedThing	transforming growth factor beta complex	A protein complex acting as ligand of the transforming growth factor beta receptor complex, typically a homodimer of any of the TFGbeta isoforms. The precursor of TGFbeta proteins is cleaved into mature TGFbeta and the latency-associated peptide (LAP), which remains non-covalently linked to mature TGFbeta rendering it inactive. TGFbeta is activated by dimerisation and dissociation of the LAP.	tmpzr1t_l9r_go_relaxed.owl	TGFbeta dimer|TGFB complex|TGFB dimer|TGF-beta dimer|TGFbeta complex|TGF-beta complex													cellular_component											owl:Class	
GO:0019178	biolink:NamedThing	NADP phosphatase activity	Catalysis of the reaction: H2O + NADP+ = NAD+ + phosphate.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:NADPPHOSPHAT-RXN									molecular_function											owl:Class	
GO:2000524	biolink:NamedThing	negative regulation of T cell costimulation	Any process that stops, prevents or reduces the frequency, rate or extent of T cell costimulation.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of T-cell costimulation|negative regulation of T lymphocyte costimulation|negative regulation of T-lymphocyte costimulation|negative regulation of T cell co-stimulation|negative regulation of T-cell co-stimulation							ebc	2011-03-23T10:23:31Z					biological_process											owl:Class	
GO:0006272	biolink:NamedThing	leading strand elongation	The process in which an existing DNA strand is extended continuously in a 5' to 3' direction by activities including the addition of nucleotides to the 3' end of the strand, complementary to an existing template, as part of DNA replication. Leading strand elongation proceeds in the same direction as the replication fork.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/12633												biological_process											owl:Class	
GO:1904903	biolink:NamedThing	ESCRT III complex disassembly	The disaggregation of an ESCRT III complex into its constituent components.	tmpzr1t_l9r_go_relaxed.owl								pad	2016-01-18T13:38:14Z					biological_process											owl:Class	
GO:1904896	biolink:NamedThing	ESCRT complex disassembly	The disaggregation of an ESCRT complex into its constituent components.	tmpzr1t_l9r_go_relaxed.owl	endosomal sorting complex required for transport disassembly							pad	2016-01-12T10:27:30Z					biological_process											owl:Class	
GO:0000426	biolink:NamedThing	micropexophagy	Degradation of a peroxisome by lysosomal microautophagy.	tmpzr1t_l9r_go_relaxed.owl						Note that this term is not a child of pexophagy because the community usually uses the latter to refer to the macroautohagy process.								biological_process											owl:Class	
GO:0140712	biolink:NamedThing	negative regulation of Frizzled Nuclear Import pathway	Any process that stops, prevents, or reduces the frequency, rate or extent of a Frizzled Nuclear Import pathway.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of FNI|negative regulation of Frizzled Nuclear Import Wnt Pathway	https://github.com/geneontology/go-ontology/issues/21483						pg	2021-09-08T09:18:32Z					biological_process											owl:Class	
GO:0061145	biolink:NamedThing	lung smooth muscle development	The process whose specific outcome is the progression of smooth muscle in the lung over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-05-25T10:46:35Z					biological_process											owl:Class	
GO:0070393	biolink:NamedThing	teichoic acid catabolic process	The chemical reactions and pathways resulting in the breakdown of teichoic acid, which is a major component of the cell wall of Gram-positive bacteria and typically consists of a polymer of glycerol-phosphate or ribitol-phosphate to which are attached glycosyl and D-alanyl ester residues.	tmpzr1t_l9r_go_relaxed.owl	teichoic acid degradation|teichoic acid catabolism|teichoic acid breakdown													biological_process											owl:Class	
GO:1904682	biolink:NamedThing	cellular response to 3-methylcholanthrene	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 3-methylcholanthrene stimulus.	tmpzr1t_l9r_go_relaxed.owl								mr	2015-09-22T19:50:10Z					biological_process											owl:Class	
GO:1903166	biolink:NamedThing	cellular response to polycyclic arene	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a polycyclic arene stimulus.	tmpzr1t_l9r_go_relaxed.owl								mr	2014-07-09T18:33:04Z					biological_process											owl:Class	
GO:0042467	biolink:NamedThing	orthokinesis	The movement of a cell or organism in response to a stimulus in which the speed or frequency of movement is increased or decreased.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0042465	biolink:NamedThing	kinesis	The movement of a cell or organism in response to a stimulus in which the rate of movement depends on the intensity (rather than the direction) of the stimulus.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Kinesis									biological_process											owl:Class	
GO:0043618	biolink:NamedThing	regulation of transcription from RNA polymerase II promoter in response to stress	Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:2000218	biolink:NamedThing	negative regulation of invasive growth in response to glucose limitation	Any process that stops, prevents, or reduces the frequency, rate or extent of invasive growth in response to glucose limitation.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of colony morphology							mah	2010-11-03T04:36:00Z					biological_process											owl:Class	
GO:1901053	biolink:NamedThing	sarcosine catabolic process	The chemical reactions and pathways resulting in the breakdown of sarcosine.	tmpzr1t_l9r_go_relaxed.owl	sarcosine breakdown|sarcosine degradation|sarcosine catabolism							yaf	2012-06-28T04:52:29Z					biological_process											owl:Class	
GO:0051474	biolink:NamedThing	glucosylglycerol transmembrane transporter activity	Enables the transfer of a glucosylglycerol from one side of a membrane to the other. A glucosylglycerol is an alpha-D-glucopyranosyl-alpha-(1,2)-glycerol.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1905450	biolink:NamedThing	negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis	Any process that stops, prevents or reduces the frequency, rate or extent of Fc-gamma receptor signaling pathway involved in phagocytosis.	tmpzr1t_l9r_go_relaxed.owl	downregulation of Fcgamma receptor-mediated phagocytosis|down regulation of Fc-gamma receptor signalling pathway involved in phagocytosis|down-regulation of IgG-mediated phagocytosis|negative regulation of Fc gamma receptor-dependent phagocytosis|inhibition of IgG-mediated phagocytosis|negative regulation of Fcgamma receptor-mediated phagocytosis|down regulation of IgG-mediated phagocytosis|down regulation of Fc gamma receptor-dependent phagocytosis|down-regulation of Fc gamma receptor-dependent phagocytosis|down regulation of Fcgamma receptor-mediated phagocytosis|downregulation of Fc-gamma receptor signaling pathway involved in phagocytosis|down-regulation of Fc-gamma receptor signalling pathway involved in phagocytosis|inhibition of Fcgamma receptor-mediated phagocytosis|downregulation of IgG-mediated phagocytosis|negative regulation of IgG-mediated phagocytosis|downregulation of Fc-gamma receptor signalling pathway involved in phagocytosis|inhibition of Fc gamma receptor-dependent phagocytosis|inhibition of Fc-gamma receptor signaling pathway involved in phagocytosis|down regulation of Fc-gamma receptor signaling pathway involved in phagocytosis|down-regulation of Fc-gamma receptor signaling pathway involved in phagocytosis|negative regulation of Fc-gamma receptor signalling pathway involved in phagocytosis|down-regulation of Fcgamma receptor-mediated phagocytosis|inhibition of Fc-gamma receptor signalling pathway involved in phagocytosis|downregulation of Fc gamma receptor-dependent phagocytosis							sl	2016-09-15T19:41:58Z					biological_process											owl:Class	
GO:0019579	biolink:NamedThing	aldaric acid catabolic process	The chemical reactions and pathways resulting in the breakdown of aldaric acid, any dicarboxylic acid formed by oxidation of by the terminal groups of an aldose to carboxyl group.	tmpzr1t_l9r_go_relaxed.owl	aldaric acid degradation|aldaric acid breakdown|aldaric acid catabolism													biological_process											owl:Class	
GO:0006069	biolink:NamedThing	ethanol oxidation	An ethanol metabolic process in which ethanol is converted to acetyl-CoA via acetaldehyde and acetate.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1904017	biolink:NamedThing	cellular response to Thyroglobulin triiodothyronine	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a Thyroglobulin triiodothyronine stimulus.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-03-06T19:34:13Z					biological_process											owl:Class	
GO:2001229	biolink:NamedThing	negative regulation of response to gamma radiation	Any process that stops, prevents or reduces the frequency, rate or extent of response to gamma radiation.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of response to gamma-ray photon|negative regulation of response to gamma ray							yaf	2011-11-20T04:51:14Z					biological_process											owl:Class	
GO:0071276	biolink:NamedThing	cellular response to cadmium ion	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cadmium (Cd) ion stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to cadmium							mah	2009-12-10T03:54:49Z					biological_process											owl:Class	
GO:2001063	biolink:NamedThing	glucomannan binding	Binding to glucomannan.	tmpzr1t_l9r_go_relaxed.owl								jl	2011-09-14T10:29:45Z					molecular_function											owl:Class	
GO:0010297	biolink:NamedThing	heteropolysaccharide binding	Binding to a heteropolysaccharide, a glycan composed of more than one type of monosaccharide residue.	tmpzr1t_l9r_go_relaxed.owl	heteroglycan binding													molecular_function											owl:Class	
GO:1902390	biolink:NamedThing	regulation of N-terminal peptidyl-serine acetylation	Any process that modulates the frequency, rate or extent of N-terminal peptidyl-serine acetylation.	tmpzr1t_l9r_go_relaxed.owl								al	2013-09-11T14:46:45Z					biological_process											owl:Class	
GO:0044508	biolink:NamedThing	glucagon-like peptide 1 receptor activity	Combining with glucagon-like peptide 1 and transmitting the signal across the membrane by activating an associated G-protein.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-02-23T04:50:25Z					molecular_function											owl:Class	
GO:1900487	biolink:NamedThing	regulation of [2Fe-2S] cluster assembly	Any process that modulates the frequency, rate or extent of [2Fe-2S] cluster assembly.	tmpzr1t_l9r_go_relaxed.owl	regulation of [2Fe-2S] cluster biosynthetic process|regulation of 2Fe-2S cluster assembly							tt	2012-05-02T01:22:22Z					biological_process											owl:Class	
GO:1990359	biolink:NamedThing	stress response to zinc ion	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis caused by a zinc ion stimulus.	tmpzr1t_l9r_go_relaxed.owl	stress response to zinc|response to zinc toxicity|response to zinc ion stress							kmv	2014-04-14T15:54:05Z					biological_process											owl:Class	
GO:0010043	biolink:NamedThing	response to zinc ion	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a zinc ion stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to zinc													biological_process											owl:Class	
GO:0120242	biolink:NamedThing	2-iminobutanoate deaminase activity	Catalysis of the reaction: 2-iminobutanoate + H2O = 2-oxobutanoate + NH4(+).	tmpzr1t_l9r_go_relaxed.owl	2-iminobutanoate/2-iminopropanoate deaminase	https://github.com/geneontology/go-ontology/issues/19832			MetaCyc:RXN-15123|RHEA:39975|KEGG_REACTION:R11098			krc	2020-07-29T18:07:00Z					molecular_function											owl:Class	
GO:0043828	biolink:NamedThing	tRNA 2-selenouridine synthase activity	Catalysis of the reaction: 5-methylaminomethyl-2-thiouridine + selenophosphate = 5-methylaminomethyl-2-selenouridine + phosphate (at the wobble position in tRNA).	tmpzr1t_l9r_go_relaxed.owl					EC:2.9.1.3|RHEA:42716|MetaCyc:RXN0-2281									molecular_function											owl:Class	
GO:0004115	biolink:NamedThing	3',5'-cyclic-AMP phosphodiesterase activity	Catalysis of the reaction: adenosine 3',5'-cyclic phosphate + H2O = adenosine 5'-phosphate.	tmpzr1t_l9r_go_relaxed.owl	3',5'-cyclic-AMP-specific phosphodiesterase activity|cAMP-specific phosphodiesterase activity|adenosine 3',5'-cyclophosphate-specific phosphodiesterase activity|cyclic AMP-specific phosphodiesterase activity|3',5' cAMP-specific phosphodiesterase activity|3',5'-cAMP-specific phosphodiesterase activity				MetaCyc:RXN0-5038|RHEA:25277|Reactome:R-HSA-9644869|Reactome:R-HSA-111962|Reactome:R-HSA-9629675|Reactome:R-HSA-418553|EC:3.1.4.53|Reactome:R-HSA-9705507									molecular_function											owl:Class	
GO:1903696	biolink:NamedThing	protein localization to horsetail-astral microtubule array	A process in which a protein is transported to, or maintained in, a location within a horsetail-astral microtubule array.	tmpzr1t_l9r_go_relaxed.owl	protein localisation to horsetail-astral microtubule array|protein localisation in horsetail-astral microtubule array|protein localization in horsetail-astral microtubule array							mah	2014-12-03T10:58:18Z					biological_process											owl:Class	
GO:0072699	biolink:NamedThing	protein localization to cortical microtubule cytoskeleton	A process in which a protein is transported to, or maintained at, a location within the cortical microtubule cytoskeleton.	tmpzr1t_l9r_go_relaxed.owl	protein localisation to cortical microtubule cytoskeleton							mah	2012-04-11T01:23:36Z					biological_process											owl:Class	
GO:0052643	biolink:NamedThing	chlorophyllide metabolic process	The chemical reactions and pathways involving chlorophyllides, any chlorophyll lacking the terpenoid side chain such as phytyl or farnesyl.	tmpzr1t_l9r_go_relaxed.owl	chlorophyllide metabolism													biological_process											owl:Class	
GO:0005751	biolink:NamedThing	mitochondrial respiratory chain complex IV	A protein complex located in the mitochondrial inner membrane that forms part of the mitochondrial respiratory chain. Contains the 13 polypeptide subunits of cytochrome c oxidase, including cytochrome a and cytochrome a3. Catalyzes the oxidation of reduced cytochrome c by dioxygen (O2).	tmpzr1t_l9r_go_relaxed.owl												GO:0005752		cellular_component											owl:Class	
GO:0045277	biolink:NamedThing	respiratory chain complex IV	A part of the respiratory chain, containing the 13 polypeptide subunits of cytochrome c oxidase, including cytochrome a and cytochrome a3. Catalyzes the oxidation of reduced cytochrome c by dioxygen (O2).	tmpzr1t_l9r_go_relaxed.owl	electron transport complex IV|cytochrome c oxidase complex											GO:0045287		cellular_component											owl:Class	
GO:0110098	biolink:NamedThing	positive regulation of calcium import into the mitochondrion	Any process that activates or increases the frequency, rate or extent of calcium import into the mitochondrion.	tmpzr1t_l9r_go_relaxed.owl								kmv	2018-02-28T00:39:13Z					biological_process											owl:Class	
GO:0003062	biolink:NamedThing	regulation of heart rate by chemical signal	The regulation of the rate of heart contraction mediated by chemical signaling, hormonal, autocrine or paracrine.	tmpzr1t_l9r_go_relaxed.owl	chemical signal regulation of heart contraction rate|chemical cardiac chronotropy|chemical signal regulation of heart rate													biological_process											owl:Class	
GO:0051614	biolink:NamedThing	inhibition of serotonin uptake	Any process that prevents the activation of the directed movement of serotonin into a cell.	tmpzr1t_l9r_go_relaxed.owl	inhibition of 5-hydroxytryptamine uptake|inhibition of 5-HT uptake|inhibition of 5HT uptake|inhibition of serotonin import													biological_process											owl:Class	
GO:0052822	biolink:NamedThing	DNA-3-methylguanine glycosylase activity	Catalysis of the reaction: DNA containing 3-methylguanine + H2O = DNA with abasic site + 3-methylguanine. This reaction is the hydrolysis of DNA by cleavage of the N-C1' glycosidic bond between the damaged DNA 3-methylguanine and the deoxyribose sugar to remove the 3-methylguanine, leaving an abasic site.	tmpzr1t_l9r_go_relaxed.owl	deoxyribonucleate 3-methylguanine glycosidase I|3-methylguanine DNA glycosylase I|alkylated-DNA glycohydrolase (releasing methyladenine and methylguanine)|DNA glycosidase I activity				MetaCyc:3.2.2.21-RXN|EC:3.2.2.21			ai	2011-10-28T02:28:19Z					molecular_function											owl:Class	
GO:0070878	biolink:NamedThing	primary miRNA binding	Binding to a primary microRNA (pri-miRNA) transcript, an RNA molecule that is processed into a short hairpin-shaped structure called a pre-miRNA and finally into a functional miRNA. Both double-stranded and single-stranded regions of a pri-miRNA are required for binding.	tmpzr1t_l9r_go_relaxed.owl	pri-miRNA binding|primary microRNA binding							mah	2009-08-20T04:11:36Z					molecular_function											owl:Class	
GO:0061120	biolink:NamedThing	regulation of positive chemotaxis to cAMP by DIF-1	Any process that modulates the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of DIF-1. DIF-1 is a chlorinated alkylphenone.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-05-17T08:10:20Z					biological_process											owl:Class	
GO:0008208	biolink:NamedThing	C21-steroid hormone catabolic process	The chemical reactions and pathways resulting in the breakdown of C21-steroid hormones, steroid compounds containing 21 carbons which function as hormones.	tmpzr1t_l9r_go_relaxed.owl	C21-steroid hormone degradation|C21-steroid hormone breakdown|C21-steroid hormone catabolism													biological_process											owl:Class	
GO:0062047	biolink:NamedThing	pipecolic acid N-hydroxylase	Catalysis of the reaction: L-pipecolic acid + NAD(P)H + O2 + H+ = N-hydroxypipecolic acid + NAD(P)+ + H2O.	tmpzr1t_l9r_go_relaxed.owl								dph	2018-05-11T12:17:15Z					molecular_function											owl:Class	
GO:0072237	biolink:NamedThing	metanephric proximal tubule development	The process whose specific outcome is the progression of the metanephric proximal tubule over time, from its formation to the mature structure. The metanephric proximal tubule is a metanephric nephron tubule that connects Bowman's capsule to the descending thin limb of the loop of Henle in the metanephros. It has a brush border epithelial morphology.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-03-18T03:46:54Z					biological_process											owl:Class	
GO:0001582	biolink:NamedThing	detection of chemical stimulus involved in sensory perception of sweet taste	The series of events required for a sweet taste stimulus to be received and converted to a molecular signal.	tmpzr1t_l9r_go_relaxed.owl	perception of sweet taste, sensory transduction of chemical stimulus|sensory transduction of sweet taste|sensory detection of chemical stimulus during perception of sweet taste|sensory transduction of chemical stimulus during perception of sweet taste|perception of sweet taste, detection of chemical stimulus|sensory detection of sweet taste|sweet taste detection													biological_process											owl:Class	
GO:0030933	biolink:NamedThing	chloroplast ADPG pyrophosphorylase complex	An ADPG pyrophosphorylase complex found in the chloroplast.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0019875	biolink:NamedThing	6-aminohexanoate-dimer hydrolase activity	Catalysis of the reaction: N-(6-aminohexanoyl)-6-aminohexanoate + H2O = 2 6-aminohexanoate.	tmpzr1t_l9r_go_relaxed.owl	6-aminohexanoic acid oligomer hydrolase activity|N-(6-aminohexanoyl)-6-aminohexanoate amidohydrolase activity				UM-BBD_enzymeID:e0673|MetaCyc:RXN-3962|EC:3.5.1.46|RHEA:21364									molecular_function											owl:Class	
GO:0046332	biolink:NamedThing	SMAD binding	Binding to a SMAD signaling protein.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0031949	biolink:NamedThing	regulation of glucocorticoid catabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glucocorticoids.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0046970	biolink:NamedThing	NAD-dependent histone deacetylase activity (H4-K16 specific)	Catalysis of the reaction: histone H4 N6-acetyl-L-lysine (position 16) + H2O = histone H4 L-lysine (position 16) + acetate. This reaction requires the presence of NAD, and represents the removal of an acetyl group from lysine at position 16 of the histone H4 protein.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0006659	biolink:NamedThing	phosphatidylserine biosynthetic process	The chemical reactions and pathways resulting in the formation of phosphatidylserines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of L-serine.	tmpzr1t_l9r_go_relaxed.owl	phosphatidylserine biosynthesis|phosphatidylserine formation|phosphatidylserine synthesis|phosphatidylserine anabolism													biological_process											owl:Class	
GO:1900020	biolink:NamedThing	positive regulation of protein kinase C activity	Any process that activates or increases the frequency, rate or extent of protein kinase C activity.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of PKC activity|positive regulation of PKC|up regulation of PKC|up regulation of PKC activity							bf	2012-01-11T03:50:55Z					biological_process											owl:Class	
GO:0034109	biolink:NamedThing	homotypic cell-cell adhesion	The attachment of a cell to a second cell of the identical type via adhesion molecules.	tmpzr1t_l9r_go_relaxed.owl						Note that this term is not synonymous with 'homophilic cell adhesion ; GO:0007156'; the process may occur by homophilic or heterophilic mechanisms.								biological_process											owl:Class	
GO:1904631	biolink:NamedThing	response to glucoside	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucoside stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to glucosides							sl	2015-08-28T14:01:31Z					biological_process											owl:Class	
GO:1900873	biolink:NamedThing	pentadec-1-ene biosynthetic process	The chemical reactions and pathways resulting in the formation of pentadec-1-ene.	tmpzr1t_l9r_go_relaxed.owl	pentadec-1-ene formation|pentadec-1-ene synthesis|pentadec-1-ene biosynthesis|pentadec-1-ene anabolism							tt	2012-06-13T01:45:45Z					biological_process											owl:Class	
GO:0016437	biolink:NamedThing	tRNA cytidylyltransferase activity	Catalysis of the reaction: CTP + tRNA(n) = diphosphate + tRNA(n+1).	tmpzr1t_l9r_go_relaxed.owl	-C-C-A pyrophosphorylase|CTP:tRNA cytidylyltransferase activity|transfer ribonucleic adenylyl (cytidylyl) transferase|transfer ribonucleate nucleotidyltransferase|tRNA CCA-diphosphorylase activity|ATP (CTP):tRNA nucleotidyltransferase|transfer RNA adenylyltransferase|transfer ribonucleate adenylyltransferase|tRNA CCA-pyrophosphorylase activity|transfer ribonucleate cytidylyltransferase|ATP(CTP)-tRNA nucleotidyltransferase|transfer-RNA nucleotidyltransferase|transfer ribonucleic acid nucleotidyl transferase|ATP(CTP):tRNA nucleotidyltransferase activity|ribonucleic cytidylyltransferase|ribonucleic cytidylic cytidylic adenylic pyrophosphorylase|transfer ribonucleic-terminal trinucleotide nucleotidyltransferase|CTP(ATP):tRNA nucleotidyltransferase|tRNA adenylyl(cytidylyl)transferase				EC:2.7.7.72|MetaCyc:TRNA-CYTIDYLYLTRANSFERASE-RXN									molecular_function											owl:Class	
GO:0042429	biolink:NamedThing	serotonin catabolic process	The chemical reactions and pathways resulting in the breakdown of serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties.	tmpzr1t_l9r_go_relaxed.owl	serotonin breakdown|serotonin catabolism|serotonin degradation													biological_process											owl:Class	
GO:0060487	biolink:NamedThing	lung epithelial cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of an epithelial cell that contributes to the epithelium of the lung.	tmpzr1t_l9r_go_relaxed.owl	pulmonary epithelial cell differentiation													biological_process											owl:Class	
GO:0050251	biolink:NamedThing	retinol isomerase activity	Catalysis of the reaction: all-trans-retinol = 11-cis-retinol.	tmpzr1t_l9r_go_relaxed.owl	all-trans-retinol isomerase activity|all-trans-retinol 11-cis-trans-isomerase activity				RHEA:19141|KEGG_REACTION:R02369|Reactome:R-HSA-2465926|MetaCyc:RETINOL-ISOMERASE-RXN									molecular_function											owl:Class	
GO:0009951	biolink:NamedThing	polarity specification of dorsal/ventral axis	Any process resulting in the establishment of polarity along the dorsal/ventral axis.	tmpzr1t_l9r_go_relaxed.owl	polarity specification of dorsoventral axis|polarity specification of dorsal-ventral axis													biological_process											owl:Class	
GO:0065001	biolink:NamedThing	specification of axis polarity	The pattern specification process in which the polarity of a body or organ axis is established and maintained.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0102014	biolink:NamedThing	beta-D-galactose-importing ATPase activity	Catalysis of the reaction: ATP(4-) + beta-D-galactoside + H2O <=> ADP(3-) + hydrogenphosphate + beta-D-galactoside + H+.	tmpzr1t_l9r_go_relaxed.owl					RHEA:30011|MetaCyc:ABC-18-RXN									molecular_function											owl:Class	
GO:0015407	biolink:NamedThing	ABC-type monosaccharide transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + monosaccharide(out) = ADP + phosphate + monosaccharide(in). Ribose, xylose, arabinose, galactose and methylgalactoside are imported.	tmpzr1t_l9r_go_relaxed.owl	monosaccharide-transporting ATPase activity|monosaccharide ABC transporter|ATPase-coupled monosaccharide transmembrane transporter activity|ATP-dependent monosaccharide transmembrane transporter activity|monosaccharide-importing ATPase activity	https://github.com/geneontology/go-ontology/issues/17289			MetaCyc:3.6.3.17-RXN|EC:7.5.2.-									molecular_function											owl:Class	
GO:0008045	biolink:NamedThing	motor neuron axon guidance	The process in which the migration of an axon growth cone of a motor neuron is directed to a specific target site in response to a combination of attractive and repulsive cues.	tmpzr1t_l9r_go_relaxed.owl	motor axon guidance|motoneuron axon guidance|motor axon pathfinding													biological_process											owl:Class	
GO:1901781	biolink:NamedThing	p-cumate metabolic process	The chemical reactions and pathways involving p-cumate.	tmpzr1t_l9r_go_relaxed.owl	p-cumate metabolism							yaf	2013-01-16T10:40:28Z					biological_process											owl:Class	
GO:0102789	biolink:NamedThing	UDP-D-glucose:cyanidin 5-O-beta-D-glucosyltransferase activity	Catalysis of the reaction: UDP-alpha-D-glucose + cyanidin = H+ + cyanidin 5-O-beta-D-glucoside + UDP.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-8005									molecular_function											owl:Class	
GO:0004980	biolink:NamedThing	melanocyte-stimulating hormone receptor activity	Combining with melanocyte-stimulating hormone to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	MSH receptor activity|melanocyte stimulating hormone receptor activity|melanophore-stimulating hormone receptor activity|MSHR activity													molecular_function											owl:Class	
GO:0004977	biolink:NamedThing	melanocortin receptor activity	Combining with melanocortin to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0019760	biolink:NamedThing	glucosinolate metabolic process	The chemical reactions and pathways involving glucosinolates, substituted thioglucosides found in rapeseed products and related cruciferae. They are metabolized to a variety of toxic products which are most likely the cause of hepatocytic necrosis in animals and humans.	tmpzr1t_l9r_go_relaxed.owl	glucosinolate metabolism													biological_process											owl:Class	
GO:0033049	biolink:NamedThing	clavulanic acid metabolic process	The chemical reactions and pathways involving clavulanic acid, (2R,3Z,5R)-3-(2-hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo[3.2.0]heptane-2-carboxylic acid.	tmpzr1t_l9r_go_relaxed.owl	clavulanic acid metabolism													biological_process											owl:Class	
GO:0018249	biolink:NamedThing	protein dehydration	The removal of a water group from a protein amino acid.	tmpzr1t_l9r_go_relaxed.owl	protein amino acid dehydration													biological_process											owl:Class	
GO:0030932	biolink:NamedThing	amyloplast ADPG pyrophosphorylase complex	An ADPG pyrophosphorylase complex found in the amyloplast.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0010437	biolink:NamedThing	9,10 (9', 10')-carotenoid-cleaving dioxygenase activity	Catalysis of the oxidative cleavage of carotenoids at the (9, 10) and/or (9', 10') double bond.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0010436	biolink:NamedThing	carotenoid dioxygenase activity	Catalysis of the oxidative cleavage of carotenoids.	tmpzr1t_l9r_go_relaxed.owl	carotenoid-cleaving dioxygenase													molecular_function											owl:Class	
GO:0060714	biolink:NamedThing	labyrinthine layer formation	The developmental process pertaining to the initial formation of the labyrinthine layer of the placenta.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-06-10T08:13:14Z					biological_process											owl:Class	
GO:0050309	biolink:NamedThing	sugar-terminal-phosphatase activity	Catalysis of the reaction: H2O + sugar phosphorylated on the terminal carbon = a sugar + phosphate.	tmpzr1t_l9r_go_relaxed.owl	sugar-omega-phosphate phosphohydrolase activity|xylitol-5-phosphatase activity				EC:3.1.3.58									molecular_function											owl:Class	
GO:0060022	biolink:NamedThing	hard palate development	The biological process whose specific outcome is the progression of the hard palate from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. The hard palate is the anterior portion of the palate consisting of bone and mucous membranes.	tmpzr1t_l9r_go_relaxed.owl	palatum durum development													biological_process											owl:Class	
GO:0048577	biolink:NamedThing	negative regulation of short-day photoperiodism, flowering	Any process that stops, prevents or reduces short-day photoperiodism, where the response associated with the photoperiodism is flowering. Flowering is defined by the switch from the vegetative to the reproductive phase.	tmpzr1t_l9r_go_relaxed.owl	downregulation of short-day photoperiodism, flowering|down-regulation of short-day photoperiodism, flowering|down regulation of short-day photoperiodism, flowering|inhibition of short-day photoperiodism, flowering													biological_process											owl:Class	
GO:0071056	biolink:NamedThing	alpha9-beta1 integrin-ADAM15 complex	A protein complex that consists of an alpha9-beta1 integrin complex bound to the transmembrane metallopeptidase ADAM15.	tmpzr1t_l9r_go_relaxed.owl	ITGA9-ITGB1-ADAM15 complex							mah	2009-11-03T03:59:49Z					cellular_component											owl:Class	
GO:0039514	biolink:NamedThing	suppression by virus of host JAK-STAT cascade	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of the JAK-STAT signal cascade in the host organism.	tmpzr1t_l9r_go_relaxed.owl	inhibition by virus of host JAK-STAT cascade|negative regulation by virus of host JAK-STAT cascade|downregulation by virus of host JAK-STAT cascade|down-regulation by virus of host JAK-STAT cascade							bf	2011-06-16T02:48:03Z					biological_process											owl:Class	
GO:0043006	biolink:NamedThing	activation of phospholipase A2 activity by calcium-mediated signaling	A series of molecular signals that leads to the upregulation of calcium-dependent phospholipase A2 activity in response to the signal.	tmpzr1t_l9r_go_relaxed.owl	calcium-dependent phospholipase A2 activation|calcium-dependent activation of phospholipase A2|activation of phospholipase A2 activity by calcium-mediated signalling													biological_process											owl:Class	
GO:0032431	biolink:NamedThing	activation of phospholipase A2 activity	Any process that initiates the activity of the inactive enzyme phospholipase A2.	tmpzr1t_l9r_go_relaxed.owl	phospholipase A2 activation													biological_process											owl:Class	
GO:0061783	biolink:NamedThing	peptidoglycan muralytic activity	A catalytic activity that contributes to the degradation of peptidoglycan.	tmpzr1t_l9r_go_relaxed.owl								dph	2016-09-07T15:47:49Z					molecular_function											owl:Class	
GO:0052820	biolink:NamedThing	DNA-1,N6-ethenoadenine N-glycosylase activity	Catalysis of the reaction: DNA with 1-N6-ethenoadenine + H2O = DNA with abasic site + 1-N6-ethenoadenine. This reaction is the removal of 1,N6-ethenoadenine by cleaving the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar.	tmpzr1t_l9r_go_relaxed.owl	1,N6-ethenoadenine glycosylase activity|1,N(6)-ethenoadenine N-glycosylase activity								2011-10-28T01:17:21Z					molecular_function											owl:Class	
GO:0097054	biolink:NamedThing	L-glutamate biosynthetic process	The chemical reactions and pathways resulting in the formation of L-glutamate, the L enantiomer anion of 2-aminopentanedioic acid.	tmpzr1t_l9r_go_relaxed.owl	L-glutamate biosynthesis|L-glutamate anabolism|L-glutamate formation|L-glutamate synthesis							pr	2011-05-24T04:30:38Z					biological_process											owl:Class	
GO:0090052	biolink:NamedThing	regulation of pericentric heterochromatin assembly	Any process that modulates the frequency, rate or extent of chromatin silencing at the centromere. Chromatin silencing at the centromere is the repression of transcription of centromeric DNA by altering the structure of chromatin.	tmpzr1t_l9r_go_relaxed.owl	regulation of chromatin silencing at centromere	https://github.com/geneontology/go-ontology/issues/19112						tb	2009-08-07T10:47:41Z					biological_process											owl:Class	
GO:0044487	biolink:NamedThing	envenomation resulting in modulation of transmission of nerve impulse in other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant modulation of the transmission of nerve impulses in the bitten organism.	tmpzr1t_l9r_go_relaxed.owl	envenomation resulting in modulation of conduction of nerve impulse in other organism							jl	2012-01-26T05:01:54Z					biological_process											owl:Class	
GO:1900900	biolink:NamedThing	negative regulation of heptadecane metabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of heptadecane metabolic process.	tmpzr1t_l9r_go_relaxed.owl	downregulation of heptadecane metabolism|inhibition of heptadecane metabolism|down-regulation of heptadecane metabolic process|down-regulation of heptadecane metabolism|inhibition of heptadecane metabolic process|down regulation of heptadecane metabolism|negative regulation of heptadecane metabolism|downregulation of heptadecane metabolic process|down regulation of heptadecane metabolic process							tt	2012-06-13T03:30:25Z					biological_process											owl:Class	
GO:0008756	biolink:NamedThing	o-succinylbenzoate-CoA ligase activity	Catalysis of the reaction: 2-succinylbenzoate + ATP + CoA = 2-succinylbenzoyl-CoA + AMP + diphosphate.	tmpzr1t_l9r_go_relaxed.owl	OSB-CoA synthetase activity|o-succinylbenzoyl-coenzyme A synthetase activity|o-succinylbenzoyl-CoA synthetase activity|2-succinylbenzoate:CoA ligase (AMP-forming)|o-succinylbenzoate:CoA ligase (AMP-forming)				MetaCyc:O-SUCCINYLBENZOATE-COA-LIG-RXN|KEGG_REACTION:R04030|EC:6.2.1.26|RHEA:17009									molecular_function											owl:Class	
GO:0006270	biolink:NamedThing	DNA replication initiation	The process in which DNA-dependent DNA replication is started; this begins with the ATP dependent loading of an initiator complex onto the DNA, this is followed by DNA melting and helicase activity. In bacteria, the gene products that enable the helicase activity are loaded after the initial melting and in archaea and eukaryotes, the gene products that enable the helicase activity are inactive when they are loaded and subsequently activate.	tmpzr1t_l9r_go_relaxed.owl	DNA endoreduplication initiation|DNA re-replication initiation|DNA-dependent DNA replication initiation											GO:0042024		biological_process											owl:Class	
GO:0018515	biolink:NamedThing	pimeloyl-CoA dehydrogenase activity	Catalysis of the reaction: NAD(+) + pimelyl-CoA = 2,3-didehydropimeloyl-CoA + H(+) + NADH.	tmpzr1t_l9r_go_relaxed.owl	pimeloyl-CoA:NAD+ oxidoreductase activity				MetaCyc:1.3.1.62-RXN|KEGG_REACTION:R05311|UM-BBD_reactionID:r0194|EC:1.3.1.62|RHEA:19665									molecular_function											owl:Class	
GO:1904267	biolink:NamedThing	negative regulation of Schwann cell chemotaxis	Any process that stops, prevents or reduces the frequency, rate or extent of Schwann cell chemotaxis.	tmpzr1t_l9r_go_relaxed.owl	inhibition of Schwann cell chemotaxis|down-regulation of Schwann cell chemotaxis|down regulation of Schwann cell chemotaxis|downregulation of Schwann cell chemotaxis							sl	2015-05-28T17:47:48Z					biological_process											owl:Class	
GO:0000993	biolink:NamedThing	RNA polymerase II complex binding	Binding to an RNA polymerase II core enzyme, a multisubunit eukaryotic nuclear RNA polymerase typically composed of twelve subunits.	tmpzr1t_l9r_go_relaxed.owl	RNAP II core binding|RNA polymerase II core binding							krc	2010-08-11T03:57:27Z					molecular_function											owl:Class	
GO:1901256	biolink:NamedThing	regulation of macrophage colony-stimulating factor production	Any process that modulates the frequency, rate or extent of macrophage colony-stimulating factor production.	tmpzr1t_l9r_go_relaxed.owl	regulation of M-CSF production							vk	2012-08-10T08:28:08Z					biological_process											owl:Class	
GO:0002162	biolink:NamedThing	dystroglycan binding	Binding to dystroglycan, a glycoprotein found in non-muscle tissues as well as in muscle tissues, often in association with dystrophin. The native dystroglycan cleaved into two non-covalently associated subunits, alpha (N-terminal) and beta (C-terminal).	tmpzr1t_l9r_go_relaxed.owl	beta-dystroglycan binding|alpha-dystroglycan binding							hjd	2010-02-22T02:17:58Z			GO:0002166|GO:0002163		molecular_function											owl:Class	
GO:0030152	biolink:NamedThing	bacteriocin biosynthetic process	The chemical reactions and pathways resulting in the formation of a bacteriocin, any of a heterogeneous group of polypeptide antibiotics that are secreted by certain bacterial strains and are able to kill cells of other susceptible (frequently related) strains after adsorption at specific receptors on the cell surface. They include the colicins, and their mechanisms of action vary.	tmpzr1t_l9r_go_relaxed.owl	bacteriocin biosynthesis|bacteriocin anabolism|bacteriocin formation|bacteriocin synthesis													biological_process											owl:Class	
GO:0046224	biolink:NamedThing	bacteriocin metabolic process	The chemical reactions and pathways involving bacteriocins, any of a heterogeneous group of polypeptide antibiotics that are secreted by certain bacterial strains and are able to kill cells of other susceptible (frequently related) strains after adsorption at specific receptors on the cell surface. They include the colicins, and their mechanisms of action vary.	tmpzr1t_l9r_go_relaxed.owl	bacteriocin metabolism													biological_process											owl:Class	
GO:0060059	biolink:NamedThing	embryonic retina morphogenesis in camera-type eye	The process in which the anatomical structure of the retina is generated and organized in a camera-type eye during the embryonic life stage.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1902975	biolink:NamedThing	mitotic DNA replication initiation	Any DNA replication initiation involved in mitotic cell cycle DNA replication.	tmpzr1t_l9r_go_relaxed.owl	DNA replication initiation involved in mitotic cell cycle DNA replication							jl	2014-05-06T15:21:11Z					biological_process											owl:Class	
GO:0047386	biolink:NamedThing	fructose-2,6-bisphosphate 6-phosphatase activity	Catalysis of the reaction: beta-D-fructose 2,6-bisphosphate + H(2)O = beta-D-fructofuranose 2-phosphate + phosphate.	tmpzr1t_l9r_go_relaxed.owl	D-fructose-2,6-bisphosphate 6-phosphohydrolase activity|beta-D-fructose-2,6-bisphosphate 6-phosphohydrolase activity|fructose 2,6-bisphosphate-6-phosphohydrolase activity|fructose-2,6-bisphosphate 6-phosphohydrolase activity				RHEA:13333|KEGG_REACTION:R02730|EC:3.1.3.54|MetaCyc:3.1.3.54-RXN									molecular_function											owl:Class	
GO:1900639	biolink:NamedThing	positive regulation of asperfuranone biosynthetic process	Any process that activates or increases the frequency, rate or extent of asperfuranone biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of asperfuranone biosynthesis|positive regulation of asperfuranone anabolism|upregulation of asperfuranone biosynthetic process|upregulation of asperfuranone synthesis|up regulation of asperfuranone formation|upregulation of asperfuranone anabolism|activation of asperfuranone biosynthesis|positive regulation of asperfuranone biosynthesis|activation of asperfuranone synthesis|up regulation of asperfuranone biosynthesis|up regulation of asperfuranone synthesis|up-regulation of asperfuranone formation|upregulation of asperfuranone formation|positive regulation of asperfuranone synthesis|activation of asperfuranone biosynthetic process|up regulation of asperfuranone anabolism|up regulation of asperfuranone biosynthetic process|up-regulation of asperfuranone anabolism|positive regulation of asperfuranone formation|upregulation of asperfuranone biosynthesis|activation of asperfuranone anabolism|up-regulation of asperfuranone biosynthetic process|up-regulation of asperfuranone synthesis|activation of asperfuranone formation							di	2012-05-22T03:50:24Z					biological_process											owl:Class	
GO:0004593	biolink:NamedThing	pantothenase activity	Catalysis of the reaction: (R)-pantothenate + H(2)O = (R)-pantoate + beta-alanine.	tmpzr1t_l9r_go_relaxed.owl	pantothenate amidohydrolase activity|(R)-pantothenate amidohydrolase activity|pantothenate hydrolase activity				RHEA:12448|EC:3.5.1.22|KEGG_REACTION:R02474|MetaCyc:PANTOTHENASE-RXN									molecular_function											owl:Class	
GO:0039639	biolink:NamedThing	suppression by virus of host cell lysis in response to superinfection	The prevention or delay of host cell lysis by a pre-existing virus in response to a subsequent infection of the host cell by second virus.	tmpzr1t_l9r_go_relaxed.owl	lysis inhibition|suppression by virus of host cell lysis in response to superinfecting virus							bf	2012-08-17T10:42:27Z					biological_process											owl:Class	
GO:0098586	biolink:NamedThing	cellular response to virus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a virus.	tmpzr1t_l9r_go_relaxed.owl								dos	2014-01-24T14:54:08Z					biological_process											owl:Class	
GO:0003832	biolink:NamedThing	beta-alanyl-dopamine hydrolase activity	Catalysis of the reaction: N-beta-alanyl dopamine + H2O = dopamine + beta-alanine.	tmpzr1t_l9r_go_relaxed.owl	N-beta-alanyl-dopamine hydrolase activity|NBAD hydrolase activity													molecular_function											owl:Class	
GO:1900335	biolink:NamedThing	positive regulation of methane biosynthetic process from 3-(methylthio)propionic acid	Any process that activates or increases the frequency, rate or extent of methane biosynthetic process from 3-(methylthio)propionic acid.	tmpzr1t_l9r_go_relaxed.owl	upregulation of methane biosynthetic process from 3-(methylthio)propionic acid|up-regulation of methane biosynthetic process from 3-(methylthio)propionic acid|up regulation of methane biosynthetic process from 3-(methylthio)propionic acid|activation of methane biosynthetic process from 3-(methylthio)propionic acid							tt	2012-04-06T01:56:31Z					biological_process											owl:Class	
GO:1900064	biolink:NamedThing	positive regulation of peroxisome organization	Any process that activates or increases the frequency, rate or extent of peroxisome organization.	tmpzr1t_l9r_go_relaxed.owl	activation of peroxisome organization|positive regulation of peroxisome organization and biogenesis|activation of peroxisome organisation|up regulation of peroxisome organization|upregulation of peroxisome-assembly ATPase activity|positive regulation of peroxisome-assembly ATPase activity|up-regulation of peroxisome organisation|up-regulation of peroxisome organization|activation of peroxisome organization and biogenesis|up-regulation of peroxisome organization and biogenesis|up-regulation of peroxisome-assembly ATPase activity|up regulation of peroxisome organisation|upregulation of peroxisome organisation|positive regulation of peroxisome organisation|up regulation of peroxisome-assembly ATPase activity|upregulation of peroxisome organization|activation of peroxisome-assembly ATPase activity|upregulation of peroxisome organization and biogenesis|up regulation of peroxisome organization and biogenesis							dph	2012-01-26T01:49:09Z					biological_process											owl:Class	
GO:0070006	biolink:NamedThing	metalloaminopeptidase activity	Catalysis of the hydrolysis of a single N-terminal amino acid residue from a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/19681												molecular_function											owl:Class	
GO:0015024	biolink:NamedThing	glucuronate-2-sulfatase activity	Catalysis of the hydrolysis of the 2-sulfate groups of the 2-O-sulfo-D-glucuronate residues of chondroitin sulfate, heparin and heparitin sulfate.	tmpzr1t_l9r_go_relaxed.owl	glucurono-2-sulfatase activity|chondro-2-sulfatase activity|glucuronate-2-sulphatase activity|polysaccharide-2-O-sulfo-D-glucuronate 2-sulfohydrolase activity				EC:3.1.6.18|MetaCyc:3.1.6.18-RXN									molecular_function											owl:Class	
GO:0010294	biolink:NamedThing	abscisic acid glucosyltransferase activity	Catalysis of the reaction: (+)-abscisate + UDP-D-glucose = abscisic acid glucose ester + UDP.	tmpzr1t_l9r_go_relaxed.owl					RHEA:31031|MetaCyc:RXN-8155									molecular_function											owl:Class	
GO:0071179	biolink:NamedThing	MAML3-RBP-Jkappa-ICN1 complex	A protein complex that consists of the intracellular domain of Notch1 (ICN1), the DNA-binding transcription factor RBP-Jkappa, and the transcriptional coactivator Mastermind-like-3 (MAML3); the complex is involved in transcriptional activation in response to Notch-mediated signaling.	tmpzr1t_l9r_go_relaxed.owl	MAML3-RBP-Jkappa-Notch1 complex							mah	2009-11-23T02:50:39Z					cellular_component											owl:Class	
GO:0102988	biolink:NamedThing	9,12-cis-hexadecadienoic acid delta 15 desaturase activity	Catalysis of the reaction: (9Z,12Z)-hexadecadienoyl-CoA + O2 + a reduced electron acceptor <=> 9,12,15-cis-hexadecatrienoyl-CoA + 2 H2O + an oxidized electron acceptor.	tmpzr1t_l9r_go_relaxed.owl					RHEA:46232|MetaCyc:RXN-9617									molecular_function											owl:Class	
GO:1905681	biolink:NamedThing	negative regulation of innate immunity memory response	Any process that stops, prevents or reduces the frequency, rate or extent of innate immunity memory response.	tmpzr1t_l9r_go_relaxed.owl	inhibition of innate immunity memory response|downregulation of innate immunity memory response|down regulation of innate immunity memory response|down-regulation of innate immunity memory response							tb	2016-11-11T22:25:29Z					biological_process											owl:Class	
GO:0005136	biolink:NamedThing	interleukin-4 receptor binding	Binding to an interleukin-4 receptor.	tmpzr1t_l9r_go_relaxed.owl	interleukin-4 receptor ligand|IL-4													molecular_function											owl:Class	
GO:0016258	biolink:NamedThing	N-glycan diversification	The generation, in the Golgi apparatus, of side chain diversity from high mannose Man5GlcNAc2-Asn N-glycans by specific glycosyltransferases and glycosidases.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0045464	biolink:NamedThing	R8 cell fate specification	The process in which a cell becomes capable of differentiating autonomously into an R8 cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0043704	biolink:NamedThing	photoreceptor cell fate specification	The process in which a cell becomes capable of differentiating autonomously into a photoreceptor cell in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0102984	biolink:NamedThing	sulfoacetaldehyde dehydrogenase activity	Catalysis of the reaction: sulfonatoacetaldehyde + H2O + NAD <=> sulfonatoacetate + NADH + 2 H+.	tmpzr1t_l9r_go_relaxed.owl					RHEA:25637|MetaCyc:RXN-9592|EC:1.2.1.73									molecular_function											owl:Class	
GO:0046799	biolink:NamedThing	recruitment of helicase-primase complex to DNA lesions	The recruitment of the helicase-primase complex to viral DNA lesions during viral DNA repair.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0060703	biolink:NamedThing	deoxyribonuclease inhibitor activity	Binds to and stops, prevents or reduces the activity of deoxyribonuclease.	tmpzr1t_l9r_go_relaxed.owl	DNase inhibitor activity							dph	2009-06-08T03:00:35Z					molecular_function											owl:Class	
GO:0140721	biolink:NamedThing	nuclease inhibitor activity	Binds to and modulates the activity of a nuclease.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/16423						pg	2021-11-16T09:09:45Z					molecular_function											owl:Class	
GO:0097133	biolink:NamedThing	cyclin D3-CDK6 complex	A protein complex consisting of cyclin D3 and cyclin-dependent kinase 6 (CDK6). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner.	tmpzr1t_l9r_go_relaxed.owl								pr	2011-08-01T01:57:41Z					cellular_component											owl:Class	
GO:0071506	biolink:NamedThing	cellular response to mycophenolic acid	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mycophenolic acid stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to mycophenolate							mah	2009-12-18T03:47:25Z					biological_process											owl:Class	
GO:0002519	biolink:NamedThing	natural killer cell tolerance induction	Tolerance induction of natural killer cells.	tmpzr1t_l9r_go_relaxed.owl	NK cell tolerance induction													biological_process											owl:Class	
GO:0035907	biolink:NamedThing	dorsal aorta development	The progression of the dorsal aorta over time, from its initial formation to the mature structure. The dorsal aorta is a blood vessel in a single-pass circulatory system that carries oxygenated blood from the gills to the rest of the body. In a single-pass circulatory system blood passes once through the heart to supply the body once.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-06-24T11:07:01Z					biological_process											owl:Class	
GO:0140375	biolink:NamedThing	immune receptor activity	Receiving a signal and transmitting it in a cell to initiate an immune response.	tmpzr1t_l9r_go_relaxed.owl								pg	2019-10-18T14:11:15Z					molecular_function											owl:Class	
GO:2000232	biolink:NamedThing	regulation of rRNA processing	Any process that modulates the frequency, rate or extent of rRNA processing.	tmpzr1t_l9r_go_relaxed.owl	regulation of 35S primary transcript processing							mah	2010-11-10T12:11:29Z					biological_process											owl:Class	
GO:0071514	biolink:NamedThing	genetic imprinting	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving macromolecules by a mechanism that is mediated by DNA, is mitotically or meiotically heritable, or is stably self-propagated in the cytoplasm of a resting cell, and does not entail a change in DNA sequence.	tmpzr1t_l9r_go_relaxed.owl	DNA imprinting							mah	2010-01-06T11:56:31Z					biological_process											owl:Class	
GO:0034424	biolink:NamedThing	Vps55/Vps68 complex	A membrane-associated protein complex that is required for a late stage of endosomal transport. In budding yeast, this complex consists of Vps55p and Vps68p proteins.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0070585	biolink:NamedThing	protein localization to mitochondrion	A process in which a protein is transported to, or maintained in, a location within the mitochondrion.	tmpzr1t_l9r_go_relaxed.owl	protein localization in mitochondrion|protein localisation in mitochondrion							mah	2009-04-24T02:31:18Z					biological_process											owl:Class	
GO:0001527	biolink:NamedThing	microfibril	Extracellular matrix components occurring independently or along with elastin. Thought to have force-bearing functions in tendon. In addition to fibrillins, microfibrils may contain other associated proteins.	tmpzr1t_l9r_go_relaxed.owl	extended fibrils|fibrillin													cellular_component											owl:Class	
GO:0070667	biolink:NamedThing	negative regulation of mast cell proliferation	Any process that stops, prevents or reduces the rate or extent of mast cell proliferation.	tmpzr1t_l9r_go_relaxed.owl	inhibition of mast cell proliferation|downregulation of mast cell proliferation|down regulation of mast cell proliferation|down-regulation of mast cell proliferation							mah	2009-05-28T05:45:11Z					biological_process											owl:Class	
GO:0045746	biolink:NamedThing	negative regulation of Notch signaling pathway	Any process that stops, prevents, or reduces the frequency, rate or extent of the Notch signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	downregulation of Notch signaling pathway|negative regulation of N signalling pathway|negative regulation of Notch signalling pathway|down regulation of Notch signaling pathway|inhibition of Notch signaling pathway|negative regulation of N signaling pathway|down-regulation of Notch signaling pathway													biological_process											owl:Class	
GO:0000309	biolink:NamedThing	nicotinamide-nucleotide adenylyltransferase activity	Catalysis of the reaction: ATP + nicotinamide nucleotide = diphosphate + NAD+.	tmpzr1t_l9r_go_relaxed.owl	nicotinamide adenine dinucleotide pyrophosphorylase activity|adenosine triphosphate-nicotinamide mononucleotide transadenylase activity|NAD+ diphosphorylase activity|ATP:nicotinamide-nucleotide adenylyltransferase activity|diphosphopyridine nucleotide pyrophosphorylase activity|NMNAT activity|NAD+ pyrophosphorylase activity|NMN adenylyltransferase activity|ATP:NMN adenylyltransferase activity|nicotinamide mononucleotide adenylyltransferase activity|NAD(+) diphosphorylase activity|NAD(+) pyrophosphorylase activity				MetaCyc:2.7.7.1-RXN|RHEA:21360|EC:2.7.7.1|Reactome:R-HSA-8939959									molecular_function											owl:Class	
GO:1902019	biolink:NamedThing	regulation of cilium-dependent cell motility	Any process that modulates the frequency, rate or extent of cilium-dependent cell motility.	tmpzr1t_l9r_go_relaxed.owl	regulation of ciliary cell motility|regulation of cilium cell motility							jl	2013-03-27T14:42:38Z					biological_process											owl:Class	
GO:0007405	biolink:NamedThing	neuroblast proliferation	The expansion of a neuroblast population by cell division. A neuroblast is any cell that will divide and give rise to a neuron.	tmpzr1t_l9r_go_relaxed.owl												GO:0043350|GO:0043349		biological_process											owl:Class	
GO:0072383	biolink:NamedThing	plus-end-directed vesicle transport along microtubule	The directed movement of a vesicle towards the plus end of a microtubule, mediated by motor proteins. This process begins with the attachment of a vesicle to a microtubule, and ends when the vesicle reaches its final destination.	tmpzr1t_l9r_go_relaxed.owl	microtubule plus-end-directed vesicle localization|microtubule plus-end-directed vesicle distribution							mah	2010-12-01T04:24:51Z					biological_process											owl:Class	
GO:0075011	biolink:NamedThing	positive regulation of germ tube formation	Any process that activates, maintains or increases the frequency, rate or extent of germ tube formation on or near host. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of germ tube formation on or near host													biological_process											owl:Class	
GO:2000528	biolink:NamedThing	negative regulation of myeloid dendritic cell chemotaxis	Any process that stops, prevents or reduces the frequency, rate or extent of myeloid dendritic cell chemotaxis.	tmpzr1t_l9r_go_relaxed.owl								ebc	2011-03-23T12:18:39Z					biological_process											owl:Class	
GO:0098929	biolink:NamedThing	extrinsic component of spine apparatus membrane	The component of the spine apparatus membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0061193	biolink:NamedThing	taste bud development	The progression of the taste bud over time, from its formation to the mature state. The taste bud is a specialized area of the tongue that contains taste receptors.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-07-27T10:55:08Z					biological_process											owl:Class	
GO:0150044	biolink:NamedThing	regulation of postsynaptic dense core vesicle exocytosis	Any process that modulates the frequency, rate or extent of postsynaptic dense core vesicle exocytosis.	tmpzr1t_l9r_go_relaxed.owl								bc	2018-04-20T13:34:32Z					biological_process											owl:Class	
GO:0008863	biolink:NamedThing	formate dehydrogenase (NAD+) activity	Catalysis of the reaction: formate + NAD(+) = CO(2) + NADH.	tmpzr1t_l9r_go_relaxed.owl	NAD-formate dehydrogenase|NAD-linked formate dehydrogenase|formate:NAD+ oxidoreductase|formate hydrogenlyase|N-FDH|formate dehydrogenase (NAD)|NAD-dependent formate dehydrogenase|FDH II|formate benzyl-viologen oxidoreductase|formic hydrogen-lyase|formate-NAD oxidoreductase|FDH I|formic acid dehydrogenase				EC:1.17.1.9|RHEA:15985|MetaCyc:1.2.1.2-RXN|KEGG_REACTION:R00519|UM-BBD_reactionID:r0103|MetaCyc:FORMATEDEHYDROG-RXN							GO:0018476		molecular_function											owl:Class	
GO:0033161	biolink:NamedThing	mitogen-activated protein kinase kinase kinase kinase binding	Binding to a mitogen-activated protein kinase kinase kinase kinase, a protein that can phosphorylate a MAP kinase kinase kinase.	tmpzr1t_l9r_go_relaxed.owl	MAPKKKK binding													molecular_function											owl:Class	
GO:0120135	biolink:NamedThing	distal portion of axoneme	The portion of the axoneme that is close to the tip of the cilium.	tmpzr1t_l9r_go_relaxed.owl	distal part of axoneme							krc	2018-03-10T01:45:34Z					cellular_component											owl:Class	
GO:0004757	biolink:NamedThing	sepiapterin reductase activity	Catalysis of the reaction: 7,8-dihydrobiopterin + NADP+ = sepiapterin + NADPH + H+.	tmpzr1t_l9r_go_relaxed.owl	7,8-dihydrobiopterin:NADP+ oxidoreductase activity				Reactome:R-HSA-1475414|Reactome:R-HSA-1497869|MetaCyc:SEPIAPTERIN-REDUCTASE-RXN|RHEA:18953|EC:1.1.1.153									molecular_function											owl:Class	
GO:1902559	biolink:NamedThing	3'-phospho-5'-adenylyl sulfate transmembrane transport	The process in which 3'-phospho-5'-adenylyl sulfate is transported across a membrane.	tmpzr1t_l9r_go_relaxed.owl	3'-phosphoadenosine 5'-phosphosulfate transmembrane transport							mcc	2013-12-09T23:19:04Z					biological_process											owl:Class	
GO:0043905	biolink:NamedThing	Ser-tRNA(Thr) hydrolase activity	Catalysis of the hydrolysis of misacylated Ser-tRNA(Thr).	tmpzr1t_l9r_go_relaxed.owl	Ser-tRNAThr hydrolase activity				EC:3.1.1.-									molecular_function											owl:Class	
GO:0035338	biolink:NamedThing	long-chain fatty-acyl-CoA biosynthetic process	The chemical reactions and pathways resulting in the formation of a long-chain fatty-acyl-CoA any derivative of coenzyme A in which the sulfhydryl group is in a thioester linkage with a long-chain fatty-acyl group. Long-chain fatty-acyl-CoAs have chain lengths of C13 or more.	tmpzr1t_l9r_go_relaxed.owl	long-chain fatty-acyl-CoA synthesis|long-chain fatty-acyl-CoA anabolism|long-chain fatty-acyl-CoA biosynthesis|long-chain fatty acyl CoA biosynthetic process|long-chain fatty-acyl-CoA formation							bf	2010-03-02T11:07:15Z					biological_process											owl:Class	
GO:0035336	biolink:NamedThing	long-chain fatty-acyl-CoA metabolic process	The chemical reactions and pathways involving long-chain fatty-acyl-CoAs, any derivative of coenzyme A in which the sulfhydryl group is in a thioester linkage with a long-chain fatty-acyl group. Long-chain fatty-acyl-CoAs have chain lengths of C13 or more.	tmpzr1t_l9r_go_relaxed.owl	long-chain fatty acyl CoA metabolic process|long-chain fatty acyl-CoA metabolism							bf	2010-03-02T11:01:43Z					biological_process											owl:Class	
GO:0060244	biolink:NamedThing	negative regulation of cell proliferation involved in contact inhibition	Any process that stops, prevents or reduces the rate or extent of cell proliferation in response to cell density.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1903656	biolink:NamedThing	regulation of type IV pilus biogenesis	Any process that modulates the frequency, rate or extent of type IV pilus biogenesis.	tmpzr1t_l9r_go_relaxed.owl	regulation of type IV fimbriae assembly|regulation of type IV fimbrium assembly|regulation of type IV fimbrium biogenesis|regulation of type IV fimbriae biogenesis|regulation of type IV fimbria assembly|regulation of type IV fimbria biogenesis|regulation of type IV pilus biosynthesis|regulation of type IV fimbrial assembly|regulation of type IV fimbrial biogenesis|regulation of TFP biogenesis|regulation of type 4 pilus biogenesis							jl	2014-11-25T12:03:09Z					biological_process											owl:Class	
GO:0060491	biolink:NamedThing	regulation of cell projection assembly	Any process that modulates the rate, frequency, or extent of cell projection assembly.	tmpzr1t_l9r_go_relaxed.owl	regulation of cell projection formation													biological_process											owl:Class	
GO:1902685	biolink:NamedThing	positive regulation of receptor localization to synapse	Any process that activates or increases the frequency, rate or extent of receptor localization to synapse.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of receptor localization to synapse|upregulation of receptor localisation to synapse|activation of receptor localization to synapse|up regulation of receptor localization to synapse|up-regulation of receptor localisation to synapse|upregulation of receptor localization to synapse|up regulation of receptor localisation to synapse|positive regulation of receptor localisation to synapse|activation of receptor localisation to synapse							kmv	2014-02-07T17:38:51Z					biological_process											owl:Class	
GO:0002503	biolink:NamedThing	peptide antigen assembly with MHC class II protein complex	The binding of a peptide to the antigen binding groove of an MHC class II protein complex.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0002501	biolink:NamedThing	peptide antigen assembly with MHC protein complex	The binding of a peptide to the antigen binding groove of an MHC protein complex.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0099116	biolink:NamedThing	tRNA 5'-end processing	The process in which the 5' end of a pre-tRNA molecule is converted to that of a mature tRNA.	tmpzr1t_l9r_go_relaxed.owl	tRNA 5' processing													biological_process											owl:Class	
GO:1904373	biolink:NamedThing	response to kainic acid	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a kainic acid stimulus.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-06-18T22:42:52Z					biological_process											owl:Class	
GO:0072092	biolink:NamedThing	ureteric bud invasion	The process in which the ureteric bud grows along its axis and contributes to the formation of the metanephros.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-02-10T01:15:13Z					biological_process											owl:Class	
GO:0102799	biolink:NamedThing	glucosinolate glucohydrolase activity	Catalysis of the reaction: H2O + a glucosinolate = alpha-D-glucose + a thiohydroximate-O-sulfate.  Glucosinolates are a subclass of thioglucosides.	tmpzr1t_l9r_go_relaxed.owl					EC:3.2.1.147|MetaCyc:RXN-8134									molecular_function											owl:Class	
GO:1901216	biolink:NamedThing	positive regulation of neuron death	Any process that activates or increases the frequency, rate or extent of neuron death.	tmpzr1t_l9r_go_relaxed.owl	upregulation of neuron death|up regulation of neuron death|up-regulation of neuron cell death|activation of neuron death|upregulation of neuronal cell death|upregulation of neuron cell death|up-regulation of neuron death|activation of neuron cell death|positive regulation of neuron cell death|up-regulation of neuronal cell death|positive regulation of neuronal cell death|up regulation of neuronal cell death|up regulation of neuron cell death|activation of neuronal cell death							rph	2012-08-02T09:58:15Z					biological_process											owl:Class	
GO:0044779	biolink:NamedThing	meiotic spindle checkpoint signaling	A signal transduction process that contributes to a cell cycle checkpoint that delays the metaphase/anaphase transition of a meiotic nuclear division until the spindle is correctly assembled and that the chromosomes are attached to the spindle.	tmpzr1t_l9r_go_relaxed.owl	intracellular signal transduction involved in meiotic spindle checkpoint|intracellular signal transduction pathway involved in meiotic spindle checkpoint|intracellular signaling pathway involved in meiotic spindle checkpoint|meiotic spindle checkpoint|intracellular signaling cascade involved in meiotic spindle checkpoint	https://github.com/geneontology/go-ontology/issues/20935						jl	2013-03-21T14:01:28Z			GO:1902398		biological_process											owl:Class	
GO:1900325	biolink:NamedThing	negative regulation of maltotriulose transport	Any process that stops, prevents or reduces the frequency, rate or extent of maltotriulose transport.	tmpzr1t_l9r_go_relaxed.owl	down regulation of maltotriulose transport|downregulation of maltotriulose transport|down-regulation of maltotriulose transport|inhibition of maltotriulose transport							tt	2012-04-06T01:48:16Z					biological_process											owl:Class	
GO:0048207	biolink:NamedThing	vesicle targeting, rough ER to cis-Golgi	The process in which vesicles are directed to specific destination membranes during transport from the rough endoplasmic reticulum to the cis-Golgi.	tmpzr1t_l9r_go_relaxed.owl	rough ER to cis-Golgi targeting|vesicle targeting, rough endoplasmic reticulum to cis-Golgi|rough endoplasmic reticulum to cis-Golgi targeting													biological_process											owl:Class	
GO:0044845	biolink:NamedThing	chain elongation of O-linked mannose residue	Extension of the O-linked mannose residue of a mannoprotein by the stepwise addition of further mannose molecules.	tmpzr1t_l9r_go_relaxed.owl						Example annotations to this term include the S. cerevisiae alpha1,2-mannosyltransferases ScKre2p, ScKtr1p and ScKtr3pof the KTR family.		jl	2014-05-08T15:56:39Z					biological_process											owl:Class	
GO:0072627	biolink:NamedThing	interleukin-28A production	The appearance of interleukin-28A due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	tmpzr1t_l9r_go_relaxed.owl	IL-28A production|IL28A production|interleukin-28A secretion|interferon lambda 2 production					Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.						GO:0072628		biological_process											owl:Class	
GO:0035799	biolink:NamedThing	ureter maturation	A developmental process, independent of morphogenetic (shape) change, that is required for the ureter to attain its fully functional state. The ureter is a muscular tube that transports urine from the kidney to the urinary bladder or from the Malpighian tubule to the hindgut.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-04-14T01:13:39Z					biological_process											owl:Class	
GO:0150002	biolink:NamedThing	distal dendrite	The dendrite of the dendritic tree that is farthest away from the neuronal cell body (the soma).	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0018002	biolink:NamedThing	N-terminal peptidyl-glutamic acid acetylation	The acetylation of the N-terminal glutamic acid of proteins to form the derivate acetyl-glutamic acid.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0044	See also the molecular function term 'aspartate N-acetyltransferase activity ; GO:0017188'.								biological_process											owl:Class	
GO:0032527	biolink:NamedThing	protein exit from endoplasmic reticulum	The directed movement of proteins from the endoplasmic reticulum.	tmpzr1t_l9r_go_relaxed.owl	protein exit from ER|protein export from ER|protein export from endoplasmic reticulum													biological_process											owl:Class	
GO:1990718	biolink:NamedThing	axonemal central pair projection	Part of the 9+2 axoneme, that occurs in most motile cilia, consisting of the projections off of the central pair of single microtubules.	tmpzr1t_l9r_go_relaxed.owl								krc	2015-03-27T22:43:01Z					cellular_component											owl:Class	
GO:2000252	biolink:NamedThing	negative regulation of feeding behavior	Any process that stops, prevents or reduces the frequency, rate or extent of feeding behavior.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of feeding behaviour|negative regulation of behavioural response to food|negative regulation of behavioral response to food|negative regulation of drinking|negative regulation of eating							yaf	2010-11-18T11:24:14Z					biological_process											owl:Class	
GO:0018881	biolink:NamedThing	bromoxynil metabolic process	The chemical reactions and pathways involving bromoxynil, C7H3Br2NO, a dibrominated phenol derivative with a cyano (-CN) group attached. Bromoxynil is used as a herbicide for post-emergent control of annual broadleaf weeds and works by inhibiting photosynthesis in the target plants.	tmpzr1t_l9r_go_relaxed.owl	bromoxynil metabolism				UM-BBD_pathwayID:box									biological_process											owl:Class	
GO:1905831	biolink:NamedThing	negative regulation of spindle assembly	Any process that stops, prevents or reduces the frequency, rate or extent of spindle assembly.	tmpzr1t_l9r_go_relaxed.owl	down regulation of bipolar spindle formation|negative regulation of bipolar spindle formation|down-regulation of spindle assembly|inhibition of bipolar spindle biosynthesis|downregulation of bipolar spindle formation|down-regulation of bipolar spindle biosynthesis|negative regulation of bipolar spindle biosynthesis|down regulation of spindle biosynthesis|inhibition of spindle assembly|negative regulation of spindle formation|downregulation of spindle assembly|down regulation of bipolar spindle biosynthesis|downregulation of bipolar spindle biosynthesis|down regulation of spindle assembly|inhibition of bipolar spindle formation|downregulation of spindle formation|negative regulation of spindle biosynthesis|inhibition of spindle formation|down regulation of spindle formation|inhibition of spindle biosynthesis|down-regulation of bipolar spindle formation|down-regulation of spindle formation|down-regulation of spindle biosynthesis|downregulation of spindle biosynthesis							hbye	2017-01-17T10:26:37Z					biological_process											owl:Class	
GO:1902116	biolink:NamedThing	negative regulation of organelle assembly	Any process that stops, prevents or reduces the frequency, rate or extent of organelle assembly.	tmpzr1t_l9r_go_relaxed.owl	downregulation of organelle assembly|down regulation of organelle assembly|down-regulation of organelle assembly|inhibition of organelle assembly							pr	2013-05-14T09:43:31Z					biological_process											owl:Class	
GO:0015591	biolink:NamedThing	D-ribose transmembrane transporter activity	Enables the transfer of D-ribose from one side of a membrane to the other. As beta-D-ribofuranose, D-ribose forms the glycose group of all ribonucleosides, ribonucleotides and ribonucleic acids, and also of ribose phosphates, various glycosides, some coenzymes and some forms of vitamin B12.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0034656	biolink:NamedThing	nucleobase-containing small molecule catabolic process	The chemical reactions and pathways resulting in the breakdown of a nucleobase-containing small molecule: a nucleobase, a nucleoside, or a nucleotide.	tmpzr1t_l9r_go_relaxed.owl	nucleobase, nucleoside and nucleotide degradation|nucleobase, nucleoside and nucleotide breakdown|nucleobase, nucleoside and nucleotide catabolism													biological_process											owl:Class	
GO:0140093	biolink:NamedThing	esBAF complex	An embryonic stem cell-specific SWI/SNF-type complex that contains eight or nine proteins, including both conserved (core) and nonconserved components; contains the ATPase product of either the SMARCA4/BAF190A/BRG1 gene, the mammalian ortholog of the yeast SNF2 gene, or an ortholog thereof. Compared to many other BAF complexes never contains ACTL6B/BAF53B, ARID1B/BAF250B, SMARCA2/BRM, SMARCC2/BAF170 or SMARCD3/BAF60C but contains PHF10/BAF45A, DPF2/BAF45D and possibly one of BCL7A/B/C.	tmpzr1t_l9r_go_relaxed.owl	embryonic stem cell-specific SWI/SNF complex|embryonic stem cell-specific BAF complex							pg	2017-09-05T09:23:51Z					cellular_component											owl:Class	
GO:0045640	biolink:NamedThing	regulation of basophil differentiation	Any process that modulates the frequency, rate or extent of basophil differentiation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0047411	biolink:NamedThing	2-(acetamidomethylene)succinate hydrolase activity	Catalysis of the reaction: 2 H2O + 2-(acetamidomethylene)succinate = CO2 + NH3 + succinate semialdehyde + acetate.	tmpzr1t_l9r_go_relaxed.owl	alpha-(N-acetylaminomethylene)succinic acid hydrolase activity|2-(acetamidomethylene)succinate amidohydrolase (deaminating, decarboxylating)				MetaCyc:3.5.1.29-RXN|EC:3.5.1.29|RHEA:10432									molecular_function											owl:Class	
GO:0070929	biolink:NamedThing	trans-translation	A translational elongation process in which transfer of a translating ribosome from one mRNA to another RNA template takes place. Trans-translation occurs during tmRNA release of stalled ribosomes.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-09-16T04:06:12Z					biological_process											owl:Class	
GO:0044357	biolink:NamedThing	regulation of rRNA stability	Any process that modulates the propensity of rRNA molecules to degradation. Includes processes that both stabilize and destabilize rRNAs.	tmpzr1t_l9r_go_relaxed.owl	regulation of ribosomal RNA stability							jl	2011-08-31T09:57:54Z					biological_process											owl:Class	
GO:0046058	biolink:NamedThing	cAMP metabolic process	The chemical reactions and pathways involving the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate).	tmpzr1t_l9r_go_relaxed.owl	cAMP metabolism|cyclic AMP metabolic process|3',5'-cAMP metabolism|3',5' cAMP metabolic process|cyclic AMP metabolism|3',5'-cAMP metabolic process|cAMP generating peptide activity|adenosine 3',5'-cyclophosphate metabolic process|3',5' cAMP metabolism|adenosine 3',5'-cyclophosphate metabolism													biological_process											owl:Class	
GO:0002366	biolink:NamedThing	leukocyte activation involved in immune response	A change in morphology and behavior of a leukocyte resulting from exposure to a specific antigen, mitogen, cytokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response.	tmpzr1t_l9r_go_relaxed.owl	immune cell activation during immune response|leucocyte activation during immune response|leukocyte activation during immune response													biological_process											owl:Class	
GO:0047650	biolink:NamedThing	alkylglycerone kinase activity	Catalysis of the reaction: O-alkylglycerone + ATP = O-alkylglycerone phosphate + ADP + 2 H(+).	tmpzr1t_l9r_go_relaxed.owl	ATP:O-alkylglycerone phosphotransferase activity|alkyldihydroxyacetone kinase activity|alkyldihydroxyacetone kinase (phosphorylating)				RHEA:23088|KEGG_REACTION:R03944|EC:2.7.1.84|MetaCyc:ALKYLGLYCERONE-KINASE-RXN									molecular_function											owl:Class	
GO:0008678	biolink:NamedThing	2-deoxy-D-gluconate 3-dehydrogenase activity	Catalysis of the reaction: 2-deoxy-D-gluconate + NAD+ = 3-dehydro-2-deoxy-D-gluconate + NADH + H+.	tmpzr1t_l9r_go_relaxed.owl	2-deoxygluconate dehydrogenase activity|2-keto-3-deoxygluconate oxidoreductase activity|2-deoxy-D-gluconate:NAD+ 3-oxidoreductase activity				EC:1.1.1.125|MetaCyc:KDUD-RXN|RHEA:12160									molecular_function											owl:Class	
GO:1905754	biolink:NamedThing	ascospore-type prospore nucleus	Any nucleus that is part of a ascospore-type prospore.	tmpzr1t_l9r_go_relaxed.owl	cell nucleus of ascospore-type prospore|nucleus of ascospore-type prospore							al	2016-12-12T13:25:00Z					cellular_component											owl:Class	
GO:2000360	biolink:NamedThing	negative regulation of binding of sperm to zona pellucida	Any process that stops, prevents or reduces the frequency, rate or extent of binding of sperm to the zona pellucida.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of ZPG binding							yaf	2011-02-03T02:42:54Z					biological_process											owl:Class	
GO:0022893	biolink:NamedThing	low-affinity tryptophan transmembrane transporter activity	Catalysis of the low-affinity transfer of L-tryptophan from one side of a membrane to the other. Tryptophan is 2-amino-3-(1H-indol-3-yl)propanoic acid. In low-affinity transport the transporter is able to bind the solute only if it is present at very high concentrations.	tmpzr1t_l9r_go_relaxed.owl	low-affinity tryptophan permease activity											GO:0015510		molecular_function											owl:Class	
GO:0015196	biolink:NamedThing	L-tryptophan transmembrane transporter activity	Enables the transfer of L-tryptophan from one side of a membrane to the other. Tryptophan is 2-amino-3-(1H-indol-3-yl)propanoic acid.	tmpzr1t_l9r_go_relaxed.owl	L-tryptophan transporter activity|L-tryptophan permease activity|valine/tyrosine/tryptophan permease activity				Reactome:R-HSA-8870352							GO:0005299		molecular_function											owl:Class	
GO:0044300	biolink:NamedThing	cerebellar mossy fiber	An axon arising from cerebellar projecting cells in the cochlea, vestibular nuclei, spinal cord, reticular formation, cerebellar nuclei and basilar pontine nuclei. Mossy fibers enter through all three cerebellar peduncles and send collaterals to the deep cerebellar nuclei, then branch in the white matter and terminate in the granule cell layer. Through this branching, a given mossy fiber can innervate several folia. Mossy fibers synapse on granule cells. The synaptic contacts are made at enlargements along the length of the mossy fiber called mossy fiber rosettes. The enlargements of the rosettes give the axons a mossy-looking appearance in Golgi stained preparations.	tmpzr1t_l9r_go_relaxed.owl	cerebellar mossy fibre				NIF_Subcellular:nlx_subcell_20090209			jl	2010-02-05T11:16:40Z					cellular_component											owl:Class	
GO:0033524	biolink:NamedThing	sinapate ester metabolic process	The chemical reactions and pathways involving ester derivatives of sinapate, (2E)-3-(4-hydroxy-3,5-dimethoxyphenyl)prop-2-enoate.	tmpzr1t_l9r_go_relaxed.owl	sinapate ester metabolism													biological_process											owl:Class	
GO:0044608	biolink:NamedThing	peptidyl-L-threonine methyl ester biosynthetic process from peptidyl-threonine	The modification of a C-terminal peptidyl-threonine to form peptidyl-L-threonine methyl ester.	tmpzr1t_l9r_go_relaxed.owl	peptidyl-threonine esterification				RESID:AA0507			jl	2012-05-30T02:47:57Z					biological_process											owl:Class	
GO:0034675	biolink:NamedThing	integrin alpha6-beta1 complex	An integrin complex that comprises one alpha6 subunit and one beta1 subunit.	tmpzr1t_l9r_go_relaxed.owl	ITGA6-ITGB1 complex|VLA-6 complex|alpha6-beta1 integrin complex													cellular_component											owl:Class	
GO:0048941	biolink:NamedThing	posterior lateral line nerve glial cell development	The process aimed at the progression of a glial cell in the posterior lateral line nerve over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0090673	biolink:NamedThing	endothelial cell-matrix adhesion	The binding of an endothelial cell to the extracellular matrix via adhesion molecules.	tmpzr1t_l9r_go_relaxed.owl								tb	2016-01-15T15:38:11Z					biological_process											owl:Class	
GO:0034282	biolink:NamedThing	ent-pimara-8(14),15-diene synthase activity	Catalysis of the reaction: ent-copalyl diphosphate = ent-pimara-8(14),15-diene + diphosphate.	tmpzr1t_l9r_go_relaxed.owl	ent-copalyl-diphosphate diphosphate-lyase [ent-pimara-8(14),15-diene-forming] activity|ent-pimaradiene synthase activity				EC:4.2.3.30|RHEA:25540|KEGG_REACTION:R09121|MetaCyc:RXN-7788									molecular_function											owl:Class	
GO:0033905	biolink:NamedThing	xylan endo-1,3-beta-xylosidase activity	Catalysis of the random hydrolysis of (1->3)-beta-D-glycosidic linkages in (1->3)-beta-D-xylans.	tmpzr1t_l9r_go_relaxed.owl	endo-1,3-beta-xylanase activity|1,3-beta-xylanase activity|endo-1,3-xylanase activity|1,3-xylanase activity|xylanase activity|1,3-beta-D-xylan xylanohydrolase activity|endo-beta-1,3-xylanase activity|beta-1,3-xylanase activity				EC:3.2.1.32|MetaCyc:3.2.1.32-RXN									molecular_function											owl:Class	
GO:1905944	biolink:NamedThing	positive regulation of formation of growth cone in injured axon	Any process that activates or increases the frequency, rate or extent of formation of growth cone in injured axon.	tmpzr1t_l9r_go_relaxed.owl	upregulation of formation of growth cone in injured axon|activation of formation of growth cone in injured axon|up regulation of formation of growth cone in injured axon|up-regulation of formation of growth cone in injured axon							rz	2017-02-13T09:09:21Z					biological_process											owl:Class	
GO:1901202	biolink:NamedThing	negative regulation of extracellular matrix assembly	Any process that stops, prevents or reduces the frequency, rate or extent of extracellular matrix assembly.	tmpzr1t_l9r_go_relaxed.owl	downregulation of extracellular matrix assembly|inhibition of extracellular matrix assembly|down-regulation of extracellular matrix assembly|down regulation of extracellular matrix assembly							rl	2012-07-27T04:04:24Z					biological_process											owl:Class	
GO:2000209	biolink:NamedThing	regulation of anoikis	Any process that modulates the frequency, rate or extent of anoikis.	tmpzr1t_l9r_go_relaxed.owl	regulation of detachment induced cell death|regulation of suspension induced apoptosis							mah	2010-11-03T02:00:33Z					biological_process											owl:Class	
GO:0098825	biolink:NamedThing	peptidyl-histidine guanylation	The guanylylation of peptidyl-histidine to form (phospho-5'-guanosine)-L-histidine.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0325									biological_process											owl:Class	
GO:0061373	biolink:NamedThing	mammillary axonal complex development	The progression of the mammillary axonal complex over time, from its formation to the mature structure. The mammillary axonal complex is formed by the axons from the lateral, medial mammillary and the dorsal premammillary nuclei which share a branching pattern. Every neuron gives off one axonal stem that bifurcates into 2 branches. One of the branches is directed dorsally to the thalamus and another caudally to the midbrain.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-11-09T08:49:59Z					biological_process											owl:Class	
GO:0003149	biolink:NamedThing	membranous septum morphogenesis	The process in which the membranous septum is generated and organized. The membranous septum is the upper part of ventricular septum.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-09-22T07:51:41Z					biological_process											owl:Class	
GO:0070529	biolink:NamedThing	L-tryptophan aminotransferase activity	Catalysis of the transfer of an amino group from L-tryptophan to an acceptor, usually a 2-oxo acid.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:2000137	biolink:NamedThing	negative regulation of cell proliferation involved in heart morphogenesis	Any process that stops, prevents, or reduces the frequency, rate or extent of cell proliferation involved in heart morphogenesis.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-09-29T12:43:55Z					biological_process											owl:Class	
GO:2000763	biolink:NamedThing	positive regulation of transcription from RNA polymerase II promoter involved in norepinephrine biosynthetic process	Any positive regulation of transcription from RNA polymerase II promoter that is involved in norepinephrine biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of transcription from Pol II promoter involved in norepinephrine anabolism|positive regulation of transcription from Pol II promoter involved in levarterenol biosynthesis|positive regulation of transcription from Pol II promoter involved in norepinephrine formation|positive regulation of transcription from Pol II promoter involved in levarterenol biosynthetic process|positive regulation of transcription from Pol II promoter involved in noradrenaline biosynthetic process|positive regulation of transcription from Pol II promoter involved in norepinephrine biosynthesis|positive regulation of transcription from Pol II promoter involved in norepinephrine synthesis|positive regulation of transcription from Pol II promoter involved in norepinephrine biosynthetic process|positive regulation of transcription from Pol II promoter involved in noradrenaline biosynthesis							vk	2011-06-18T04:14:58Z					biological_process											owl:Class	
GO:0007113	biolink:NamedThing	endomitotic cell cycle	A mitotic cell cycle in which chromosomes are replicated and sister chromatids separate, but spindle formation, nuclear membrane breakdown and nuclear division do not occur, resulting in an increased number of chromosomes in the cell.	tmpzr1t_l9r_go_relaxed.owl	endomitosis				Wikipedia:Mitosis#Endomitosis	Note that this term should not be confused with 'abortive mitotic cell cycle ; GO:0033277'. Although abortive mitosis is sometimes called endomitosis, GO:0033277 refers to a process in which a mitotic spindle forms and chromosome separation begins.								biological_process											owl:Class	
GO:0007234	biolink:NamedThing	osmosensory signaling via phosphorelay pathway	A series of molecular signals generated in response to osmotic change, as mediated through a phosphorelay system.	tmpzr1t_l9r_go_relaxed.owl	osmosensory signaling pathway via two-component system|osmolarity signalling pathway via two-component system|signal transduction during osmotic stress via two-component system|osmolarity sensing via two-component system|osmosensory signalling pathway via two-component system|osmolarity signaling pathway via two-component system													biological_process											owl:Class	
GO:0055083	biolink:NamedThing	monovalent inorganic anion homeostasis	Any process involved in the maintenance of an internal steady state of monovalent inorganic anions within an organism or cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0061749	biolink:NamedThing	forked DNA-dependent helicase activity	Unwinding a DNA helix containing forked DNA, driven by ATP hydrolysis.	tmpzr1t_l9r_go_relaxed.owl								dph	2015-11-11T13:10:51Z					molecular_function											owl:Class	
GO:0045260	biolink:NamedThing	plasma membrane proton-transporting ATP synthase complex	A proton-transporting ATP synthase complex found in the plasma membrane. Examples of this component are found in Bacterial species.	tmpzr1t_l9r_go_relaxed.owl	plasma membrane hydrogen-translocating F-type ATPase complex|hydrogen-transporting ATP synthase|proton-transporting ATP synthase complex|hydrogen-translocating F-type ATPase complex											GO:0045256		cellular_component											owl:Class	
GO:0047442	biolink:NamedThing	17-alpha-hydroxyprogesterone aldolase activity	Catalysis of the reaction: 17-alpha-hydroxyprogesterone = acetaldehyde + 4-androstene-3,17-dione.	tmpzr1t_l9r_go_relaxed.owl	17alpha-hydroxyprogesterone aldolase activity|17-alpha-hydroxyprogesterone acetaldehyde-lyase activity|17alpha-hydroxyprogesterone acetaldehyde-lyase activity|17alpha-hydroxyprogesterone acetaldehyde-lyase (4-androstene-3,17-dione-forming)|C-17/C-20 lyase activity				EC:4.1.2.30|RHEA:14753|MetaCyc:4.1.2.30-RXN									molecular_function											owl:Class	
GO:0018060	biolink:NamedThing	N-terminal peptidyl-cysteine deamination	The oxidative deamination of N-terminal peptidyl-cysteine to form pyruvic acid with an amide bond between its 1-carboxyl group and the N-terminal residue.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0034684	biolink:NamedThing	integrin alphav-beta5 complex	An integrin complex that comprises one alphav subunit and one beta5 subunit.	tmpzr1t_l9r_go_relaxed.owl	ITGAV-ITGB5 complex|alphav-beta5 integrin complex													cellular_component											owl:Class	
GO:2001315	biolink:NamedThing	UDP-4-deoxy-4-formamido-beta-L-arabinopyranose biosynthetic process	The chemical reactions and pathways resulting in the formation of a UDP-4-deoxy-4-formamido-beta-L-arabinopyranose.	tmpzr1t_l9r_go_relaxed.owl	UDP-4-deoxy-4-formamido-beta-L-arabinopyranose formation|UDP-4-deoxy-4-formamido-beta-L-arabinopyranose anabolism|UDP-4-deoxy-4-formamido-beta-L-arabinopyranose biosynthesis|UDP-4-deoxy-4-formamido-beta-L-arabinopyranose synthesis							pr	2012-03-22T01:20:05Z					biological_process											owl:Class	
GO:0030910	biolink:NamedThing	olfactory placode formation	The formation of a thickening of the neural ectoderm in the head region of the vertebrate embryo which develops into the olfactory region of the nasal cavity.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0075529	biolink:NamedThing	establishment of latency as a circular episome	A process by which a virus establishes a latent state within its host as an episome, where the viral genome remains silent in the cytoplasm or nucleus as a circular structure.	tmpzr1t_l9r_go_relaxed.owl	establishment of latency as a circular plasmid|establishment of circular plasmid latency							jl	2011-08-04T03:08:17Z					biological_process											owl:Class	
GO:0006154	biolink:NamedThing	adenosine catabolic process	The chemical reactions and pathways resulting in the breakdown of adenosine, adenine riboside, a ribonucleoside found widely distributed in cells of every type as the free nucleoside and in combination in nucleic acids and various nucleoside coenzymes.	tmpzr1t_l9r_go_relaxed.owl	adenosine catabolism|adenosine breakdown|adenosine phosphorolysis|adenosine degradation											GO:0006156		biological_process											owl:Class	
GO:0008695	biolink:NamedThing	3-phenylpropionate dioxygenase activity	Catalysis of the reaction: 3-phenylpropionate + NADH + H+ + O2 = NAD+ + cis-3-(3-carboxyethyl)-3,5-cyclohexadiene-1,2-diol.	tmpzr1t_l9r_go_relaxed.owl	3-phenylpropanoate dioxygenase activity|HcaA1A2CD|Hca dioxygenase activity|3-phenylpropanoate,NADH:oxygen oxidoreductase (2,3-hydroxylating) activity				MetaCyc:HCAMULTI-RXN|UM-BBD_enzymeID:e0307|EC:1.14.12.19|RHEA:20357									molecular_function											owl:Class	
GO:0061624	biolink:NamedThing	fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate	The chemical reactions and pathways resulting in the breakdown of fructose that results in the formation of dihydroxyacetone phosphate and glyceraldehyde-3-phosphate.	tmpzr1t_l9r_go_relaxed.owl								dph	2014-04-29T12:58:28Z					biological_process											owl:Class	
GO:0070249	biolink:NamedThing	positive regulation of natural killer cell apoptotic process	Any process that activates or increases the frequency, rate or extent of natural killer cell death by apoptotic process.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of natural killer cell apoptosis|activation of natural killer cell apoptosis|positive regulation of NK cell apoptosis|upregulation of natural killer cell apoptosis|stimulation of natural killer cell apoptosis|up regulation of natural killer cell apoptosis|up-regulation of natural killer cell apoptosis													biological_process											owl:Class	
GO:0140064	biolink:NamedThing	peptide crotonyltransferase activity	Catalysis of the reaction: crotonyl-CoA + lysine in peptide = CoA + N-crotonyl-lysine-peptide.	tmpzr1t_l9r_go_relaxed.owl	protein crotonyltransferase activity							pg	2017-07-20T16:40:57Z					molecular_function											owl:Class	
GO:0034079	biolink:NamedThing	butanediol biosynthetic process	The chemical reactions and pathways resulting in the formation of butanediol; the biologically relevant isomer is 2,3-butanediol, CH3CH(OH)CH(OH)CH3.	tmpzr1t_l9r_go_relaxed.owl	butanediol biosynthesis|butylene glycol biosynthetic process|butanediol formation|butylene glycol biosynthesis|butanediol synthesis|butanediol anabolism				MetaCyc:P125-PWY									biological_process											owl:Class	
GO:0061769	biolink:NamedThing	ribosylnicotinate kinase activity	Catalysis of the reaction: N-ribosylnicotinate + ATP = ADP + 2 H(+) + nicotinate mononucleotide.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-8869607|Reactome:R-HSA-8869606			dph	2016-05-05T14:41:44Z					molecular_function											owl:Class	
GO:0102745	biolink:NamedThing	dihydrogeranylgeranyl-PP reductase activity	Catalysis of the reaction: H+ + dihydrogeranylgeranyl-PP + NADPH = tetrahydrogeranylgeranyl-PP + NADP.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-7659									molecular_function											owl:Class	
GO:0042686	biolink:NamedThing	regulation of cardioblast cell fate specification	Any process that mediates the specification of a cell into a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0000366	biolink:NamedThing	intergenic mRNA trans splicing	The joining together of two independently transcribed RNAs from two different genes, each of which also produces mRNA(s) via cis-splicing.	tmpzr1t_l9r_go_relaxed.owl	intergenic nuclear mRNA trans splicing													biological_process											owl:Class	
GO:0000365	biolink:NamedThing	mRNA trans splicing, via spliceosome	The joining together of exons from two different primary transcripts of messenger RNA (mRNA) via a spliceosomal mechanism, so that mRNA consisting only of the joined exons is produced.	tmpzr1t_l9r_go_relaxed.owl	nuclear mRNA trans splicing, via U2-type spliceosome|nuclear mRNA trans splicing, via spliceosome													biological_process											owl:Class	
GO:0060858	biolink:NamedThing	vesicle-mediated transport involved in floral organ abscission	The directed movement of substances within a cell by a cellular process that begins with the formation of membrane-bounded vesicles in which the transported substances are enclosed or located in the vesicle membrane which are then targeted to, and fuse with, an acceptor membrane contributing to the shedding of a floral organ.	tmpzr1t_l9r_go_relaxed.owl	membrane trafficking involved in floral organ shedding							dph	2009-08-12T03:48:54Z					biological_process											owl:Class	
GO:1903000	biolink:NamedThing	regulation of lipid transport across blood-brain barrier	Any process that modulates the frequency, rate or extent of lipid transport across blood-brain barrier.	tmpzr1t_l9r_go_relaxed.owl	regulation of lipid transport across blood brain barrier							sjp	2014-05-09T09:30:04Z					biological_process											owl:Class	
GO:1990020	biolink:NamedThing	recurrent axon collateral	Axon collateral that ramifies in the area of the soma of the cell of origin.	tmpzr1t_l9r_go_relaxed.owl	recurrent collateral				NIF_Subcellular:sao1642494436			pr	2013-01-10T16:04:31Z					cellular_component											owl:Class	
GO:0016715	biolink:NamedThing	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen	Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from reduced ascorbate and one other donor, and one atom of oxygen is incorporated into one donor.	tmpzr1t_l9r_go_relaxed.owl					EC:1.14.17.-									molecular_function											owl:Class	
GO:0046056	biolink:NamedThing	dADP metabolic process	The chemical reactions and pathways involving dADP, deoxyadenosine diphosphate (2'-deoxyadenosine 5'-diphosphate).	tmpzr1t_l9r_go_relaxed.owl	dADP metabolism													biological_process											owl:Class	
GO:0006163	biolink:NamedThing	purine nucleotide metabolic process	The chemical reactions and pathways involving a purine nucleotide, a compound consisting of nucleoside (a purine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.	tmpzr1t_l9r_go_relaxed.owl	purine metabolism|purine metabolic process|purine nucleotide metabolism													biological_process											owl:Class	
GO:0000705	biolink:NamedThing	achiasmate meiosis I	The first division of meiosis in which homologous chromosomes are paired and segregated from each other, occurring in the constitutive absence of chiasmata.	tmpzr1t_l9r_go_relaxed.owl	achiasmate meiosis I nuclear division													biological_process											owl:Class	
GO:0048374	biolink:NamedThing	regulation of lateral mesodermal cell fate determination	Any process that modulates the frequency, rate or extent of lateral mesoderm cell fate determination.	tmpzr1t_l9r_go_relaxed.owl	regulation of lateral mesoderm cell fate determination|regulation of lateral plate mesoderm cell fate determination|regulation of lateral plate mesodermal cell fate determination													biological_process											owl:Class	
GO:0062160	biolink:NamedThing	spongiome	A cellular anatomical entity which is a network of tubules and vessicles and is part of the contractile vacuole complex. It is involved in the discharge of water externally. One of its functions is osmoregulatory.	tmpzr1t_l9r_go_relaxed.owl								dph	2019-09-26T14:30:41Z					cellular_component											owl:Class	
GO:0047841	biolink:NamedThing	dehydrogluconokinase activity	Catalysis of the reaction: 2-dehydro-D-gluconate + ATP = 6-phospho-2-dehydro-D-gluconate + ADP + 2 H(+).	tmpzr1t_l9r_go_relaxed.owl	dehydogluconokinase activity|ketogluconokinase activity|ketogluconokinase (phosphorylating)|2-ketogluconokinase activity|2-ketogluconate kinase activity|ATP:2-dehydro-D-gluconate 6-phosphotransferase activity				KEGG_REACTION:R02658|EC:2.7.1.13|RHEA:10788|MetaCyc:DEHYDOGLUCONOKINASE-RXN									molecular_function											owl:Class	
GO:0021544	biolink:NamedThing	subpallium development	The process whose specific outcome is the progression of the subpallium over time, from its formation to the mature structure. The subpallium is the base region of the telencephalon.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0061173	biolink:NamedThing	positive regulation of establishment of bipolar cell polarity	Any process that increases the rate, frequency or extent of the establishment of bipolar cell polarity.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-06-30T08:59:20Z					biological_process											owl:Class	
GO:0050332	biolink:NamedThing	thiamine pyridinylase activity	Catalysis of the reaction: pyridine + thiamine = 5-(2-hydroxyethyl)-4-methylthiazole + heteropyrithiamine.	tmpzr1t_l9r_go_relaxed.owl	thiamin pyridinylase activity|thiamine:base 2-methyl-4-aminopyrimidine-5-methenyltransferase activity|thiamine pyridinolase activity|thiamin hydrolase activity|thiamin pyridinolase activity|thiamin:base 2-methyl-4-aminopyrimidine-5-methenyltransferase activity|thiamine hydrolase activity|pyrimidine transferase activity|thiaminase I activity				KEGG_REACTION:R02863|EC:2.5.1.2|MetaCyc:THIAMIN-PYRIDINYLASE-RXN|RHEA:17697									molecular_function											owl:Class	
GO:0050802	biolink:NamedThing	circadian sleep/wake cycle, sleep	The part of the circadian sleep/wake cycle where the organism is asleep.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0050612	biolink:NamedThing	arsenate reductase (donor) activity	Catalysis of the reaction: A + arsenite + H(2)O = AH(2) + arsenate + 2 H(+).	tmpzr1t_l9r_go_relaxed.owl	arsenate:(acceptor) oxidoreductase activity|arsenate:acceptor oxidoreductase activity				EC:1.20.99.1|MetaCyc:1.20.99.1-RXN|RHEA:18449|KEGG_REACTION:R05752									molecular_function											owl:Class	
GO:0110020	biolink:NamedThing	regulation of actomyosin structure organization	Any process that modulates the frequency, rate or extent of the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures containing both actin and myosin or paramyosin.	tmpzr1t_l9r_go_relaxed.owl								kmv	2017-06-20T19:28:58Z					biological_process											owl:Class	
GO:0009020	biolink:NamedThing	tRNA (guanosine-2'-O-)-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing 2'-O-methylguanosine.	tmpzr1t_l9r_go_relaxed.owl	tRNA guanosine-2'-O-methyltransferase activity|tRNA (Gm18) 2'-O-methyltransferase activity|S-adenosyl-L-methionine:tRNA (guanosine-2'-O-)-methyltransferase activity|tRNA (guanosine 2')-methyltransferase activity|S-adenosyl-L-methionine:tRNA guanosine-2'-O-methyltransferase activity|transfer ribonucleate guanosine 2'-methyltransferase activity|tRNA guanosine 2'-methyltransferase activity|tRNA (Gm18) methyltransferase activity				RHEA:20077|EC:2.1.1.34|Reactome:R-HSA-9024161|MetaCyc:2.1.1.34-RXN									molecular_function											owl:Class	
GO:0034461	biolink:NamedThing	uropod retraction	The process in which a uropod detaches from the cell substrate and retracts the rear of a migrating cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0032796	biolink:NamedThing	uropod organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a uropod, a rigid membrane projection with related cytoskeletal components at the trailing edge of a lymphocyte or other cell in the process of migrating or being activated.	tmpzr1t_l9r_go_relaxed.owl	uropod organisation|uropod organization and biogenesis													biological_process											owl:Class	
GO:0008507	biolink:NamedThing	sodium:iodide symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: iodide(out) + Na+(out) = iodide(in) + Na+(in).	tmpzr1t_l9r_go_relaxed.owl	sodium/iodide symporter activity				Reactome:R-HSA-429591|Reactome:R-HSA-5658195									molecular_function											owl:Class	
GO:0015373	biolink:NamedThing	anion:sodium symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: monovalent anion(out) + Na+(out) = monovalent anion(in) + Na+(in).	tmpzr1t_l9r_go_relaxed.owl	monovalent anion:sodium symporter activity													molecular_function											owl:Class	
GO:0060847	biolink:NamedThing	endothelial cell fate specification	The process involved in the specification of identity of an endothelial cell. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-08-12T11:00:04Z					biological_process											owl:Class	
GO:0018654	biolink:NamedThing	2-hydroxy-phenylacetate hydroxylase activity	Catalysis of the reaction: 2-hydroxyphenylacetate + NADH + O2 = NAD+ + OH- + homogentisate.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0252|EC:1.14.13.-									molecular_function											owl:Class	
GO:0034463	biolink:NamedThing	90S preribosome assembly	The aggregation, arrangement and bonding together of proteins and RNA molecules to form a 90S preribosome. The 90S preribosome represents the complex that forms on the primary rRNA transcript before it splits into the small subunit and large subunit portions.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0047336	biolink:NamedThing	5-methyldeoxycytidine-5'-phosphate kinase activity	Catalysis of the reaction: 2'-deoxy-5-methyl-5'-cytidylate + ATP = 5-methyldeoxycytidine diphosphate + ADP + H(+).	tmpzr1t_l9r_go_relaxed.owl	ATP:5-methyldeoxycytidine-5'-phosphate phosphotransferase activity				MetaCyc:2.7.4.19-RXN|KEGG_REACTION:R04235|EC:2.7.4.19|RHEA:11396									molecular_function											owl:Class	
GO:0030739	biolink:NamedThing	O-demethylpuromycin O-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + O-demethylpuromycin = S-adenosyl-L-homocysteine + puromycin.	tmpzr1t_l9r_go_relaxed.owl	O-demethylpuromycin methyltransferase activity|S-adenosyl-L-methionine:O-demethylpuromycin O-methyltransferase activity				RHEA:22280|MetaCyc:2.1.1.38-RXN|EC:2.1.1.38									molecular_function											owl:Class	
GO:0047249	biolink:NamedThing	sarsapogenin 3-beta-glucosyltransferase activity	Catalysis of the reaction: (25S)-5beta-spirostan-3beta-ol + UDP-D-glucose = (25S)-5beta-spirostan-3beta-yl beta-D-glucoside + H(+) + UDP.	tmpzr1t_l9r_go_relaxed.owl	UDP-glucose:(25S)-5beta-spirostan-3beta-ol 3-O-beta-D-glucosyltransferase activity|UDPglucose:(25S)-5beta-spirostan-3beta-ol 3-O-beta-D-glucosyltransferase activity|sarsapogenin 3beta-glucosyltransferase activity|uridine diphosphoglucose-sarsapogenin glucosyltransferase activity				KEGG_REACTION:R04359|MetaCyc:2.4.1.193-RXN|EC:2.4.1.193|RHEA:14461									molecular_function											owl:Class	
GO:0042474	biolink:NamedThing	middle ear morphogenesis	The process in which the anatomical structures of the middle ear are generated and organized. The middle ear is the air-filled cavity within the skull of vertebrates that lies between the outer ear and the inner ear. It is linked to the pharynx (and therefore to outside air) via the Eustachian tube and in mammals contains the three ear ossicles, which transmit auditory vibrations from the outer ear (via the tympanum) to the inner ear (via the oval window).	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0003957	biolink:NamedThing	NAD(P)+ transhydrogenase (B-specific) activity	Catalysis of the reaction: NADPH + H+ + NAD+ = NADP+ + NADH + H+, driving the transfer of a solute or solutes from one side of a membrane to the other. In the course of the reaction (left to right) one H atom is transferred from inside the cell to outside. The reaction is B-specific (i.e. the pro-S hydrogen is transferred from the 4-position of reduced nicotinamide cofactor) with respect to both NAD+ and NADP+.	tmpzr1t_l9r_go_relaxed.owl	H+-thase|NADPH:NAD+ oxidoreductase (B-specific)|NADH transhydrogenase|NAD transhydrogenase|pyridine nucleotide transferase|NADPH-NAD transhydrogenase|NAD(P) transhydrogenase (B-specific) activity|NADH-NADP-transhydrogenase|NADPH-NAD oxidoreductase|non-energy-linked transhydrogenase activity|NADPH:NAD+ transhydrogenase|nicotinamide adenine dinucleotide (phosphate) transhydrogenase|nicotinamide nucleotide transhydrogenase activity|pyridine nucleotide transhydrogenase activity				MetaCyc:PYRNUTRANSHYDROGEN-RXN|EC:1.6.1.1									molecular_function											owl:Class	
GO:0045478	biolink:NamedThing	fusome organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the fusome, a large intracellular spectrin-rich structure found in insect germline cells and mammalian hematopoietic cells.	tmpzr1t_l9r_go_relaxed.owl	fusome organization and biogenesis|fusome organisation													biological_process											owl:Class	
GO:1900131	biolink:NamedThing	negative regulation of lipid binding	Any process that stops, prevents or reduces the frequency, rate or extent of lipid binding.	tmpzr1t_l9r_go_relaxed.owl	inhibition of lipid binding|down-regulation of lipid binding|down regulation of lipid binding|downregulation of lipid binding							pm	2012-02-23T04:05:07Z					biological_process											owl:Class	
GO:0140113	biolink:NamedThing	extracellular microvesicle biogenesis	The assembly and secretion of a set of components to form an extracellular microvesicule, a membrane-bounded vesicle that ranges in size 100 nm to 1 micron in size) and exits the cell by budding.	tmpzr1t_l9r_go_relaxed.owl	extracellular microvesicle assembly	https://github.com/geneontology/go-ontology/issues/14256						pg	2017-10-23T12:00:11Z					biological_process											owl:Class	
GO:0140112	biolink:NamedThing	extracellular vesicle biogenesis	The assembly and secretion a set of components to form an extracellular vesicule, a membrane-bounded vesicle that is released into the extracellular region. Extracellular vesicles include exosomes, microvesicles and apoptotic bodies, based on the mechanism by which they are released from cells and differentiated based on their size and content.	tmpzr1t_l9r_go_relaxed.owl	extracellular vesicle assembly	https://github.com/geneontology/go-ontology/issues/14256						pg	2017-10-23T11:53:42Z					biological_process											owl:Class	
GO:0009512	biolink:NamedThing	cytochrome b6f complex	Complex that transfers electrons from reduced plastoquinone to oxidized plastocyanin and translocates protons from the stroma to the lumen. The complex contains a core structure of three catalytic subunits: cytochrome b, the Rieske iron sulfur protein (ISP), and cytochrome f, which are arranged in an integral membrane-bound dimeric complex; additional subunits are present, and vary among different species.	tmpzr1t_l9r_go_relaxed.owl	cytochrome b(6)f complex|cyt b(6)f complex|cyt b6-f complex|cyt b6/f complex|cytochrome b6/f complex|cytochrome b6-f complex|cyt b6f complex				Wikipedia:Cytochrome_b6f_complex									cellular_component											owl:Class	
GO:0070069	biolink:NamedThing	cytochrome complex	A protein complex in which at least one of the proteins is a cytochrome, i.e. a heme-containing protein involved in catalysis of redox reactions.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0005147	biolink:NamedThing	oncostatin-M receptor binding	Binding to an oncostatin-M receptor.	tmpzr1t_l9r_go_relaxed.owl	oncostatin-M|oncostatin-M receptor ligand													molecular_function											owl:Class	
GO:0052695	biolink:NamedThing	cellular glucuronidation	The modification of an organic chemical by the conjugation of glucuronic acid. The substances resulting from glucuronidation are known as glucuronosides (or glucuronides) and are often much more water-soluble than the non-glucuronic acid-containing precursor.	tmpzr1t_l9r_go_relaxed.owl	cellular glucuronoside biosynthesis|cellular glucuronoside biosynthetic process|cellular glucuronide biosynthesis|cellular glucuronide biosynthetic process								2011-07-27T05:28:18Z					biological_process											owl:Class	
GO:0099578	biolink:NamedThing	regulation of translation at postsynapse, modulating synaptic transmission	Any process that modulates synaptic transmission by regulating translation occurring at the postsynapse.	tmpzr1t_l9r_go_relaxed.owl						Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.								biological_process											owl:Class	
GO:2000474	biolink:NamedThing	regulation of opioid receptor signaling pathway	Any process that modulates the frequency, rate or extent of opioid receptor signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	regulation of opioid receptor signalling pathway							bf	2011-03-09T09:40:19Z					biological_process											owl:Class	
GO:0000330	biolink:NamedThing	plant-type vacuole lumen	The volume enclosed within the vacuolar membrane of a vacuole that retains the same shape regardless of cell cycle phase. An example of this is found in Arabidopsis thaliana.	tmpzr1t_l9r_go_relaxed.owl	lumen of vacuole with cell cycle-independent morphology													cellular_component											owl:Class	
GO:0019170	biolink:NamedThing	methylglyoxal reductase (NADH-dependent) activity	Catalysis of the reaction: (R)-lactaldehyde + NAD+ = methylglyoxal + NADH + H+.	tmpzr1t_l9r_go_relaxed.owl	methylglyoxal reductase activity|D-lactaldehyde dehydrogenase activity|(R)-lactaldehyde:NAD+ oxidoreductase activity				RHEA:24528|EC:1.1.1.78|MetaCyc:D-LACTALDEHYDE-DEHYDROGENASE-RXN									molecular_function											owl:Class	
GO:1905181	biolink:NamedThing	regulation of urease activity	Any process that modulates the frequency, rate or extent of urease activity.	tmpzr1t_l9r_go_relaxed.owl	regulation of urea amidohydrolase activity							tb	2016-05-09T23:15:54Z					biological_process											owl:Class	
GO:0031052	biolink:NamedThing	chromosome breakage	Regulated cleavage of the developing macronuclear genome at a limited number of chromosome breakage sites (CBS). The macronuclear destined segment (MDS) sequence adjacent to the CBS (or separated from it by a BES) receives a macronuclear telomere following chromosome breakage.	tmpzr1t_l9r_go_relaxed.owl	establishment or maintenance of heterochromatin architecture					Note that this term refers to breakage of chromosomes during normal DNA rearrangements characteristic of ciliates; it is not to be used for DNA damage or other abnormal occurrences.								biological_process											owl:Class	
GO:1901670	biolink:NamedThing	negative regulation of superoxide dismutase activity	Any process that stops, prevents or reduces the frequency, rate or extent of superoxide dismutase activity.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of superoxide:superoxide oxidoreductase activity|inhibition of erythrocuprein|negative regulation of copper, zinc superoxide dismutase activity|down-regulation of Fe-SOD|negative regulation of Fe-SOD|down-regulation of Mn, Fe superoxide dismutase|down-regulation of superoxide dismutase I|down-regulation of Cu-Zn superoxide dismutase activity|inhibition of superoxide dismutase II|down regulation of SODF|negative regulation of nickel superoxide dismutase activity|down-regulation of SODS|down regulation of SODS|inhibition of ferrisuperoxide dismutase activity|downregulation of SOD-1|down-regulation of nickel superoxide oxidoreductase|inhibition of Fe-SOD|downregulation of superoxide dismutase activity|down regulation of erythrocuprein|inhibition of nickel superoxide oxidoreductase|downregulation of hepatocuprein|downregulation of superoxide dismutase I|negative regulation of iron superoxide oxidoreductase|inhibition of superoxide:superoxide oxidoreductase activity|down regulation of Cu,Zn-SOD|down-regulation of hemocuprein|negative regulation of SOD-2|down-regulation of superoxide dismutase activity|down-regulation of iron superoxide dismutase activity|downregulation of superoxide:superoxide oxidoreductase activity|down-regulation of manganese superoxide dismutase activity|negative regulation of iron superoxide dismutase activity|negative regulation of cytocuprein|downregulation of iron superoxide dismutase activity|down regulation of SOD-4|down-regulation of SOD-4|inhibition of SOD-3|down regulation of cytocuprein|down regulation of hepatocuprein|down-regulation of nickel superoxide dismutase activity|negative regulation of superoxide dismutase II|downregulation of iron superoxide oxidoreductase|negative regulation of SODF|down-regulation of Cu,Zn-SOD|inhibition of Mn-SOD|down regulation of manganese superoxide oxidoreductase|down-regulation of SOD|inhibition of hemocuprein|downregulation of Fe-SOD|negative regulation of SOD-1|negative regulation of erythrocuprein|down regulation of Cu-Zn superoxide dismutase activity|down regulation of manganese superoxide dismutase activity|down-regulation of hepatocuprein|down regulation of SOD|down-regulation of SOD-2|downregulation of cytocuprein|down regulation of SOD-1|inhibition of iron superoxide oxidoreductase|inhibition of manganese superoxide dismutase activity|down regulation of superoxide dismutase activity|negative regulation of Cu-Zn superoxide dismutase activity|negative regulation of Cu,Zn-SOD|downregulation of ferrisuperoxide dismutase activity|down regulation of zinc superoxide oxidoreductase|downregulation of SOD-4|down-regulation of superoxide dismutase II|down-regulation of SODF|inhibition of nickel superoxide dismutase activity|inhibition of SODF|downregulation of superoxide dismutase II|inhibition of superoxide dismutase activity|down regulation of superoxide:superoxide oxidoreductase activity|inhibition of manganese superoxide oxidoreductase|down regulation of iron superoxide dismutase activity|downregulation of nickel superoxide dismutase activity|down regulation of cuprein|negative regulation of manganese superoxide dismutase activity|down-regulation of zinc superoxide oxidoreductase|negative regulation of hepatocuprein|down regulation of nickel superoxide oxidoreductase|inhibition of SODS|negative regulation of Mn, Fe superoxide dismutase|downregulation of nickel superoxide oxidoreductase|downregulation of SODS|negative regulation of nickel superoxide oxidoreductase|inhibition of Cu-Zn superoxide dismutase activity|downregulation of Mn, Fe superoxide dismutase|down regulation of Fe-SOD|down regulation of superoxide dismutase I|inhibition of Mn, Fe superoxide dismutase|negative regulation of superoxide:superoxide oxidoreductase activity|negative regulation of manganese superoxide oxidoreductase|down regulation of SOD-3|down-regulation of cytocuprein|downregulation of manganese superoxide oxidoreductase|inhibition of iron superoxide dismutase activity|down regulation of SOD-2|downregulation of Cu,Zn-SOD|inhibition of SOD-1|down-regulation of erythrocuprein|downregulation of zinc superoxide oxidoreductase|down regulation of ferrisuperoxide dismutase activity|inhibition of SOD|inhibition of superoxide dismutase I|down-regulation of copper, zinc superoxide dismutase activity|inhibition of zinc superoxide oxidoreductase|down-regulation of cuprein|down regulation of superoxide dismutase II|inhibition of hepatocuprein|down regulation of nickel superoxide dismutase activity|downregulation of Mn-SOD|negative regulation of hemocuprein|downregulation of cuprein|negative regulation of zinc superoxide oxidoreductase|negative regulation of cuprein|negative regulation of SOD-3|down regulation of Mn, Fe superoxide dismutase|negative regulation of SOD|inhibition of SOD-4|inhibition of cytocuprein|downregulation of SOD-2|downregulation of Cu-Zn superoxide dismutase activity|downregulation of copper, zinc superoxide dismutase activity|negative regulation of SOD-4|negative regulation of ferrisuperoxide dismutase activity|inhibition of cuprein|negative regulation of Mn-SOD|down-regulation of SOD-1|down regulation of hemocuprein|down-regulation of Mn-SOD|negative regulation of SODS|down regulation of iron superoxide oxidoreductase|inhibition of copper, zinc superoxide dismutase activity|down regulation of Mn-SOD|inhibition of SOD-2|downregulation of hemocuprein|down regulation of copper, zinc superoxide dismutase activity|down-regulation of SOD-3|down-regulation of iron superoxide oxidoreductase|down-regulation of manganese superoxide oxidoreductase|downregulation of erythrocuprein|negative regulation of superoxide dismutase I|inhibition of Cu,Zn-SOD|downregulation of SODF|downregulation of SOD-3|downregulation of SOD|down-regulation of ferrisuperoxide dismutase activity|downregulation of manganese superoxide dismutase activity							tb	2012-11-21T21:36:07Z					biological_process											owl:Class	
GO:0005117	biolink:NamedThing	wishful thinking binding	Binding to wishful thinking (Wit), a type II bone morphogenic protein receptor.	tmpzr1t_l9r_go_relaxed.owl	Wit ligand|Wit binding|wishful thinking ligand|SE20 receptor binding													molecular_function											owl:Class	
GO:1990032	biolink:NamedThing	parallel fiber	A parallel fiber results from the bifurcation of a cerebellar granule cell axon in the molecular layer into two diametrically opposed branches, that are oriented parallel to the long axis of the folium.	tmpzr1t_l9r_go_relaxed.owl					NIF_Subcellular:nlx_330			pr	2013-02-07T12:58:43Z					cellular_component											owl:Class	
GO:0097539	biolink:NamedThing	ciliary transition fiber	A nine-bladed, propeller-like protein complex that links the distal end of the basal body and the cilium to the plasma membrane. Functions in protein sorting and gating (i.e. active and passive transport of proteins in and out of the cilium).	tmpzr1t_l9r_go_relaxed.owl	transition fibre|distal appendage of centriole|cilial transition fibre|cilium transition fiber|centriolar distal appendage|ciliary transition fibre|transition fiber|distal appendage of mother centriole|cilium transition fibre|cilial transition fiber|distal appendage of basal body					In mammals, ciliary transition fibers comprise at least five components (Ccdc41/Cep83, Cep89/Cep123, Sclt1, Fbf1, and Cep164) (PMID:24469809).		pr	2013-12-03T16:46:37Z					cellular_component											owl:Class	
GO:0018294	biolink:NamedThing	protein-FAD linkage via S-(8alpha-FAD)-L-cysteine	The formation of a protein-FAD linkage via S-(8-alpha-FAD)-L-cysteine.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0143									biological_process											owl:Class	
GO:0018293	biolink:NamedThing	protein-FAD linkage	The formation of a linkage between a protein amino acid and flavin-adenine dinucleotide (FAD).	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0045630	biolink:NamedThing	positive regulation of T-helper 2 cell differentiation	Any process that activates or increases the frequency, rate or extent of T-helper 2 cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	stimulation of T-helper 2 cell differentiation|up-regulation of T-helper 2 cell differentiation|upregulation of T-helper 2 cell differentiation|up regulation of T-helper 2 cell differentiation|activation of T-helper 2 cell differentiation|positive regulation of T-helper 2 cell development					Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.								biological_process											owl:Class	
GO:0071275	biolink:NamedThing	cellular response to aluminum ion	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an aluminum ion stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to aluminum|cellular response to aluminium ion							mah	2009-12-10T03:52:20Z					biological_process											owl:Class	
GO:0038147	biolink:NamedThing	C-X-C motif chemokine 12 receptor activity	Combining with the C-X-C motif chemokine 12 (CXCL12) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	CXCR4|CXCL12 receptor activity|CXCR7|SDF-1 receptor activity|stromal cell-derived factor-1 receptor activity							bf	2012-05-11T11:32:53Z					molecular_function											owl:Class	
GO:0010169	biolink:NamedThing	thioglucosidase complex	A large (200-800 kDa) multiprotein complex formed by 70-kDa and 5-kDa myrosinases, myrosinase- binding proteins (MBPs), MBP-related proteins and myrosinase-associated proteins. The complex has been identified in Brassica napus seeds.	tmpzr1t_l9r_go_relaxed.owl	myrosinase complex													cellular_component											owl:Class	
GO:0060199	biolink:NamedThing	clathrin-sculpted glutamate transport vesicle	A clathrin-sculpted lipid bilayer membrane-enclosed vesicle after clathrin release and containing glutamate.	tmpzr1t_l9r_go_relaxed.owl	clathrin sculpted glutamate constitutive secretory pathway transport vesicle|clathrin sculpted glutamate transport vesicle													cellular_component											owl:Class	
GO:0061514	biolink:NamedThing	interleukin-34-mediated signaling pathway	A series of molecular signals initiated by the binding of interleukin-34 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.	tmpzr1t_l9r_go_relaxed.owl								dph	2013-04-18T13:00:33Z					biological_process											owl:Class	
GO:1905617	biolink:NamedThing	negative regulation of miRNA-mediated gene silencing by inhibition of translation	Any process that stops, prevents or reduces the frequency, rate or extent of miRNA-mediated gene silencing by inhibition of translation.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of downregulation of translation involved in gene silencing by miRNA|negative regulation of miRNA mediated inhibition of translation|down-regulation of gene silencing by miRNA, negative regulation of translation|down regulation of miRNA mediated inhibition of translation|downregulation of miRNA mediated inhibition of translation|down-regulation of inhibition of translation involved in gene silencing by miRNA|negative regulation of down-regulation of translation involved in gene silencing by miRNA|downregulation of negative regulation of translation involved in gene silencing by microRNA|down regulation of down-regulation of translation involved in gene silencing by miRNA|down-regulation of negative regulation of translation involved in gene silencing by microRNA|negative regulation of miRNA-mediated gene silencing, negative regulation of translation|down-regulation of miRNA-mediated gene silencing, negative regulation of translation|inhibition of negative regulation of translation involved in gene silencing by microRNA|downregulation of down-regulation of translation involved in gene silencing by miRNA|down regulation of inhibition of translation involved in gene silencing by miRNA|down-regulation of down-regulation of translation involved in gene silencing by miRNA|downregulation of inhibition of translation involved in gene silencing by miRNA|down-regulation of miRNA mediated inhibition of translation|negative regulation of negative regulation of translation involved in gene silencing by microRNA|inhibition of down regulation of translation involved in gene silencing by miRNA|downregulation of miRNA-mediated gene silencing, negative regulation of translation|inhibition of inhibition of translation involved in gene silencing by miRNA|downregulation of gene silencing by miRNA, negative regulation of translation|negative regulation of inhibition of translation involved in gene silencing by miRNA|inhibition of downregulation of translation involved in gene silencing by miRNA|down-regulation of down regulation of translation involved in gene silencing by miRNA|down regulation of gene silencing by miRNA, negative regulation of translation|down regulation of downregulation of translation involved in gene silencing by miRNA|negative regulation of down regulation of translation involved in gene silencing by miRNA|downregulation of downregulation of translation involved in gene silencing by miRNA|down regulation of down regulation of translation involved in gene silencing by miRNA|inhibition of gene silencing by miRNA, negative regulation of translation|down regulation of miRNA-mediated gene silencing, negative regulation of translation|down-regulation of downregulation of translation involved in gene silencing by miRNA|inhibition of miRNA mediated inhibition of translation|downregulation of down regulation of translation involved in gene silencing by miRNA|inhibition of miRNA-mediated gene silencing, negative regulation of translation|inhibition of down-regulation of translation involved in gene silencing by miRNA|down regulation of negative regulation of translation involved in gene silencing by microRNA|negative regulation of gene silencing by miRNA, negative regulation of translation	https://github.com/geneontology/go-ontology/issues/22389						bc	2016-10-28T11:47:57Z					biological_process											owl:Class	
GO:0052724	biolink:NamedThing	inositol hexakisphosphate 3-kinase activity	Catalysis of the reaction: ATP + 1D-myo-inositol hexakisphosphate = ADP + 3-diphospho-1D-myo-inositol (1,2,4,5,6)pentakisphosphate.	tmpzr1t_l9r_go_relaxed.owl					EC:2.7.4.21|MetaCyc:RXN-10971			ai	2011-08-16T11:50:48Z					molecular_function											owl:Class	
GO:1901464	biolink:NamedThing	negative regulation of tetrapyrrole biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of tetrapyrrole biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	down regulation of tetrapyrrole anabolism|negative regulation of tetrapyrrole formation|downregulation of tetrapyrrole anabolism|down regulation of tetrapyrrole formation|inhibition of tetrapyrrole biosynthetic process|inhibition of tetrapyrrole synthesis|down-regulation of tetrapyrrole anabolism|downregulation of tetrapyrrole biosynthetic process|down regulation of tetrapyrrole synthesis|down-regulation of tetrapyrrole biosynthetic process|down-regulation of tetrapyrrole synthesis|negative regulation of tetrapyrrole synthesis|inhibition of tetrapyrrole biosynthesis|downregulation of tetrapyrrole synthesis|down regulation of tetrapyrrole biosynthesis|inhibition of tetrapyrrole formation|negative regulation of tetrapyrrole anabolism|downregulation of tetrapyrrole formation|down regulation of tetrapyrrole biosynthetic process|down-regulation of tetrapyrrole formation|down-regulation of tetrapyrrole biosynthesis|downregulation of tetrapyrrole biosynthesis|negative regulation of tetrapyrrole biosynthesis|inhibition of tetrapyrrole anabolism							tt	2012-10-02T14:35:26Z					biological_process											owl:Class	
GO:1901402	biolink:NamedThing	negative regulation of tetrapyrrole metabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of tetrapyrrole metabolic process.	tmpzr1t_l9r_go_relaxed.owl	down regulation of tetrapyrrole metabolic process|down regulation of tetrapyrrole metabolism|down-regulation of tetrapyrrole metabolism|downregulation of tetrapyrrole metabolic process|downregulation of tetrapyrrole metabolism|negative regulation of tetrapyrrole metabolism|inhibition of tetrapyrrole metabolism|inhibition of tetrapyrrole metabolic process|down-regulation of tetrapyrrole metabolic process							tt	2012-10-01T14:35:11Z					biological_process											owl:Class	
GO:0043013	biolink:NamedThing	negative regulation of fusion of sperm to egg plasma membrane	Any process that stops or prevents the binding and fusion of a sperm to the oocyte plasma membrane.	tmpzr1t_l9r_go_relaxed.owl	inhibition of sperm-oocyte fusion|downregulation of fusion of sperm to egg plasma membrane|inhibition of fusion of sperm to egg plasma membrane|negative regulation of sperm-oocyte fusion|down regulation of fusion of sperm to egg plasma membrane|down-regulation of fusion of sperm to egg plasma membrane													biological_process											owl:Class	
GO:0009002	biolink:NamedThing	serine-type D-Ala-D-Ala carboxypeptidase activity	Catalysis of the reaction: (Ac)2-L-Lys-D-alanyl-D-alanine + H2O = (Ac)2-L-Lys-D-alanine + D-alanine.	tmpzr1t_l9r_go_relaxed.owl	DD-transpeptidase activity|DD-peptidase activity|D-alanyl carboxypeptidase activity|D-alanyl-D-alanine-cleaving peptidase activity|D-alanine carboxypeptidase|D-alanyl-D-alanine-cleaving-peptidase activity|DD-carboxypeptidase|D-alanyl-D-alanine carboxypeptidase activity|D-alanyl-D-alanine-carboxypeptidase activity				MetaCyc:3.4.16.4-RXN|EC:3.4.16.4									molecular_function											owl:Class	
GO:0102138	biolink:NamedThing	7-oxatyphasterol synthase activity	Catalysis of the reaction: H+ + typhasterol + NADPH + O2 <=> 7-oxatyphasterol + NADP + H2O.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-11538									molecular_function											owl:Class	
GO:0009420	biolink:NamedThing	bacterial-type flagellum filament	The long (approximately 20 nm), thin external structure of the bacterial-type flagellum, which acts as a propeller.	tmpzr1t_l9r_go_relaxed.owl	flagellin-based flagellum filament|flagellar filament													cellular_component											owl:Class	
GO:0034872	biolink:NamedThing	trans-geranyl-CoA isomerase activity	Catalysis of the reaction: trans-geranyl-CoA = cis-geranyl-CoA.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r1310|EC:5.2.1.-									molecular_function											owl:Class	
GO:0043879	biolink:NamedThing	glycolate transmembrane transporter activity	Enables the transfer of glycolate from one side of a membrane to the other. Glycolate is the smallest alpha-hydroxy acid (AHA).	tmpzr1t_l9r_go_relaxed.owl	hydroxyacetic acid transmembrane transporter activity|glycolate permease|glycolic acid transmembrane transporter activity|glcA				RHEA:29447									molecular_function											owl:Class	
GO:0008387	biolink:NamedThing	steroid 7-alpha-hydroxylase activity	Catalysis of the reaction: a steroid + donor-H2 + O2 = 7-alpha-hydroxysteroid + H2O.	tmpzr1t_l9r_go_relaxed.owl	cytochrome P450 CYP2A12													molecular_function											owl:Class	
GO:0062223	biolink:NamedThing	regulation of somatic muscle development	Any process that regulates the rate, frequency or extent of somatic muscle development.	tmpzr1t_l9r_go_relaxed.owl								dph	2020-03-13T18:58:37Z					biological_process											owl:Class	
GO:1901632	biolink:NamedThing	regulation of synaptic vesicle membrane organization	Any process that modulates the frequency, rate or extent of synaptic vesicle membrane organization.	tmpzr1t_l9r_go_relaxed.owl	regulation of SLMV biogenesis|regulation of synaptic vesicle membrane organisation|regulation of synaptic vesicle membrane organization and biogenesis							ans	2012-11-15T11:40:48Z					biological_process											owl:Class	
GO:1905854	biolink:NamedThing	negative regulation of heparan sulfate binding	Any process that stops, prevents or reduces the frequency, rate or extent of heparan sulfate binding.	tmpzr1t_l9r_go_relaxed.owl	down regulation of heparan sulfate binding|down-regulation of heparan sulfate binding|downregulation of heparan sulfate binding|inhibition of heparan sulfate binding							bc	2017-01-23T13:25:38Z					biological_process											owl:Class	
GO:0102376	biolink:NamedThing	lupeol 28-oxidase activity	Catalysis of the reaction: lupeol + 3 NADPH + 3 O2 + 3 H+ <=> betulinic acid + 3 NADP + 4 H2O.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-13507									molecular_function											owl:Class	
GO:0097403	biolink:NamedThing	cellular response to raffinose	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a raffinose stimulus.	tmpzr1t_l9r_go_relaxed.owl								pr	2012-10-29T10:30:46Z					biological_process											owl:Class	
GO:0018665	biolink:NamedThing	4-hydroxyphenylacetate 1-monooxygenase activity	Catalysis of the reaction: 4-hydroxyphenylacetate + NADPH + H+ + O2 = homogentisate + NADP+ + H2O.	tmpzr1t_l9r_go_relaxed.owl	4-hydroxyphenylacetate 1-hydroxylase activity|4-HPA 1-hydroxylase activity|4-hydroxyphenyl-acetate 1-hydroxylase activity|4-hydroxyphenylacetate,NAD(P)H:oxygen oxidoreductase (1-hydroxylating)|4-hydroxyphenylacetic 1-hydroxylase activity				MetaCyc:1.14.13.18-RXN|UM-BBD_reactionID:r0300|EC:1.14.13.18									molecular_function											owl:Class	
GO:0039021	biolink:NamedThing	pronephric glomerulus development	The progression of the glomerulus of the pronephric kidney over time from its initial formation until its mature state. The pronephric glomerulus is part of the pronephric nephron and is restricted to one body segment.	tmpzr1t_l9r_go_relaxed.owl						This term is intended for annotation of fish and other organisms which contain a glomerulus as part of the pronephric nephron. It should not be used for annotation of Xenopus, which contains a pronephric glomus rather than a glomerulus.		bf	2010-07-02T10:13:38Z					biological_process											owl:Class	
GO:1903999	biolink:NamedThing	negative regulation of eating behavior	Any process that stops, prevents or reduces the frequency, rate or extent of eating behavior.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of eating behaviour|inhibition of eating behaviour|downregulation of eating behavior|down-regulation of eating behavior|down-regulation of eating behaviour|down regulation of eating behaviour|down regulation of eating behavior|downregulation of eating behaviour|inhibition of eating behavior							sl	2015-03-05T20:40:28Z					biological_process											owl:Class	
GO:0102775	biolink:NamedThing	6-(4-methyl-2-oxopentyl)-4-hydroxy-2-pyrone synthase activity	Catalysis of the reaction: 2 H+ + isovaleryl-CoA + 3 malonyl-CoA = 6-(4-methyl-2-oxopentyl)-4-hydroxy-2-pyrone + 4 coenzyme A + 3 carbon dioxide.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-7826									molecular_function											owl:Class	
GO:1901448	biolink:NamedThing	regulation of response to butan-1-ol	Any process that modulates the frequency, rate or extent of response to butan-1-ol.	tmpzr1t_l9r_go_relaxed.owl								tt	2012-10-02T14:15:50Z					biological_process											owl:Class	
GO:0045787	biolink:NamedThing	positive regulation of cell cycle	Any process that activates or increases the rate or extent of progression through the cell cycle.	tmpzr1t_l9r_go_relaxed.owl	activation of progression through cell cycle|positive regulation of progression through cell cycle|up regulation of progression through cell cycle|positive regulation of cell cycle progression|upregulation of progression through cell cycle|stimulation of progression through cell cycle|up-regulation of progression through cell cycle													biological_process											owl:Class	
GO:1901715	biolink:NamedThing	regulation of gamma-aminobutyric acid catabolic process	Any process that modulates the frequency, rate or extent of gamma-aminobutyric acid catabolic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of GABA catabolic process|regulation of gamma-aminobutyric acid breakdown|regulation of 4-aminobutyrate catabolism|regulation of gamma-aminobutyric acid catabolism|regulation of gamma-aminobutyric acid degradation|regulation of GABA catabolism|regulation of 4-aminobutanoate catabolism|regulation of 4-aminobutyrate catabolic process|regulation of 4-aminobutanoate catabolic process							mcc	2012-12-19T16:13:24Z					biological_process											owl:Class	
GO:0030314	biolink:NamedThing	junctional membrane complex	Complex formed in muscle cells between the membrane of the sarcoplasmic reticulum and invaginations of the plasma membrane (T-tubules).	tmpzr1t_l9r_go_relaxed.owl	triad junction													cellular_component											owl:Class	
GO:0106008	biolink:NamedThing	2-oxoglutaramate amidase activity	Catalysis of the reaction: 2-oxoglutaramate + H(2)O = 2-oxoglutarate + NH(3).	tmpzr1t_l9r_go_relaxed.owl					EC:3.5.1.111|RHEA:32963			hjd	2017-04-25T14:10:02Z					molecular_function											owl:Class	
GO:0045852	biolink:NamedThing	pH elevation	Any process that increases the internal pH of an organism, part of an organism or a cell, measured by the concentration of the hydrogen ion.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0051472	biolink:NamedThing	glucosylglycerol metabolic process	The chemical reactions and pathways involving glucosylglycerol, alpha-D-glucopyranosyl-alpha-(1,2)-glycerol.	tmpzr1t_l9r_go_relaxed.owl	glucosylglycerol metabolism													biological_process											owl:Class	
GO:1905257	biolink:NamedThing	positive regulation of RNA binding transcription factor activity	Any process that activates or increases the frequency, rate or extent of RNA binding transcription factor activity.	tmpzr1t_l9r_go_relaxed.owl	activation of RNA binding transcription factor activity|up regulation of RNA binding transcription factor activity|up-regulation of RNA binding transcription factor activity|upregulation of RNA binding transcription factor activity							bf	2016-06-13T11:29:27Z					biological_process											owl:Class	
GO:2000442	biolink:NamedThing	positive regulation of toll-like receptor 15 signaling pathway	Any process that activates or increases the frequency, rate or extent of toll-like receptor 15 signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of TLR15 signaling pathway|positive regulation of toll-like receptor 15 signalling pathway							bf	2011-03-04T10:29:36Z					biological_process											owl:Class	
GO:0036111	biolink:NamedThing	very long-chain fatty-acyl-CoA metabolic process	The chemical reactions and pathways involving very long-chain fatty-acyl-CoAs, any derivative of coenzyme A in which the sulfhydryl group is in a thioester linkage with a medium-chain fatty-acyl group. A very long-chain fatty acid is a fatty acid which has a chain length greater than C22.	tmpzr1t_l9r_go_relaxed.owl	very long-chain fatty acyl CoA metabolic process|very long-chain fatty acyl-CoA metabolism							bf	2012-02-15T11:09:22Z					biological_process											owl:Class	
GO:1990834	biolink:NamedThing	response to odorant	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an odorant stimulus. An odorant is any substance capable of stimulating the sense of smell.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-08-21T18:51:52Z					biological_process											owl:Class	
GO:0099063	biolink:NamedThing	integral component of postsynaptic recycling endosome membrane	The component of the postsynaptic recycling endosome membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0046327	biolink:NamedThing	glycerol biosynthetic process from pyruvate	The chemical reactions and pathways resulting in the formation of glycerol, 1,2,3-propanetriol, from other compounds, including pyruvate.	tmpzr1t_l9r_go_relaxed.owl	glycerol synthesis from pyruvate|glycerol anabolism from pyruvate|glyceroneogenesis|glycerol formation from pyruvate													biological_process											owl:Class	
GO:0060406	biolink:NamedThing	positive regulation of penile erection	Any process that increases the rate, frequency or extent of penile erection. Penile erection is the hardening, enlarging and rising of the penis which often occurs in the sexually aroused male and enables sexual intercourse. Achieved by increased inflow of blood into the vessels of erectile tissue, and decreased outflow.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0042423	biolink:NamedThing	catecholamine biosynthetic process	The chemical reactions and pathways resulting in the formation of any of a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine.	tmpzr1t_l9r_go_relaxed.owl	catecholamine anabolism|catecholamine biosynthesis|catecholamine synthesis|catecholamine formation				Wikipedia:Catecholamines									biological_process											owl:Class	
GO:0018967	biolink:NamedThing	tetrachloroethylene metabolic process	The chemical reactions and pathways involving tetrachloroethylene (tetrachloroethene), a derivative of ethene with the hydrogen atoms replaced by chlorines. Tetrachloroethene has been used primarily as a solvent in dry-cleaning industries and to a lesser extent as a degreasing solvent.	tmpzr1t_l9r_go_relaxed.owl	tetrachloroethene metabolic process|tetrachloroethene metabolism|tetrachloroethylene metabolism				UM-BBD_pathwayID:tce2									biological_process											owl:Class	
GO:1905614	biolink:NamedThing	negative regulation of developmental vegetative growth	Any process that stops, prevents or reduces the frequency, rate or extent of developmental vegetative growth.	tmpzr1t_l9r_go_relaxed.owl	inhibition of developmental vegetative growth|downregulation of developmental vegetative growth|down-regulation of developmental vegetative growth|down regulation of developmental vegetative growth							pga	2016-10-28T11:45:20Z					biological_process											owl:Class	
GO:0072310	biolink:NamedThing	glomerular epithelial cell development	The process whose specific outcome is the progression of a glomerular epithelial cell over time, from its formation to the mature structure. Glomerular epithelial cells are specialized epithelial cells that form part of the glomerulus; there are two types, glomerular parietal epithelial cells and glomerular visceral epithelial cells.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-04-09T06:47:31Z					biological_process											owl:Class	
GO:0018575	biolink:NamedThing	chlorocatechol 1,2-dioxygenase activity	Catalysis of the reaction: 3,6-dichlorocatechol + O2 = 2 H+ + 2,5-dichloro-cis,cis-muconate.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0655|EC:1.13.11.-									molecular_function											owl:Class	
GO:0047605	biolink:NamedThing	acetolactate decarboxylase activity	Catalysis of the reaction: (S)-2-hydroxy-2-methyl-3-oxobutanoate = (R)-2-acetoin + CO2.	tmpzr1t_l9r_go_relaxed.owl	(S)-2-hydroxy-2-methyl-3-oxobutanoate carboxy-lyase activity|(S)-2-hydroxy-2-methyl-3-oxobutanoate carboxy-lyase [(R)-2-acetoin-forming]|alpha-acetolactate decarboxylase activity				EC:4.1.1.5|RHEA:21580|MetaCyc:ACETOLACTATE-DECARBOXYLASE-RXN									molecular_function											owl:Class	
GO:0086090	biolink:NamedThing	voltage-gated potassium channel activity involved in SA node cell action potential repolarization	Enables the transmembrane transfer of a potassium ion by a voltage-gated channel through the plasma membrane of an SA node cell contributing to the repolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.	tmpzr1t_l9r_go_relaxed.owl	voltage-gated potassium channel activity involved in sinoatrial node cell action potential|voltage-gated potassium channel activity involved in sinus node cell action potential|voltage-gated potassium channel activity involved in SAN cell action potential							dph	2011-11-22T01:38:08Z					molecular_function											owl:Class	
GO:0036379	biolink:NamedThing	myofilament	Any of the smallest contractile units of a myofibril (striated muscle fiber).	tmpzr1t_l9r_go_relaxed.owl	striated muscle filament							bf	2013-05-22T14:39:06Z					cellular_component											owl:Class	
GO:0036287	biolink:NamedThing	response to iloperidone	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iloperidone stimulus.	tmpzr1t_l9r_go_relaxed.owl						Note that this term is in the subset of terms that should not be used for direct manual annotation of gene products. It was created to be used for cross-referencing by other ontologies. Direct annotations to this term may be amended during annotation QC.		bf	2012-07-16T05:01:29Z					biological_process											owl:Class	
GO:0036262	biolink:NamedThing	granulysin production	The appearance of granulysin due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	tmpzr1t_l9r_go_relaxed.owl						Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.		bf	2012-06-18T02:11:15Z					biological_process											owl:Class	
GO:0090262	biolink:NamedThing	regulation of transcription-coupled nucleotide-excision repair	Any process that modulates the frequency, rate, or extent of the nucleotide-excision repair process that carries out preferential repair of DNA lesions on the actively transcribed strand of the DNA duplex. In addition, the transcription-coupled nucleotide-excision repair pathway is required for the recognition and repair of a small subset of lesions that are not recognized by the global genome nucleotide excision repair pathway.	tmpzr1t_l9r_go_relaxed.owl								tb	2010-02-03T04:27:42Z					biological_process											owl:Class	
GO:0048498	biolink:NamedThing	establishment of petal orientation	The process that determines the orientation of petals with reference to the central axis.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:2001098	biolink:NamedThing	tetrasaccharide transport	The directed movement of a tetrasaccharideacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl								jl	2011-09-21T02:12:53Z					biological_process											owl:Class	
GO:0032564	biolink:NamedThing	dATP binding	Binding to dATP, deoxyadenosine triphosphate.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0000769	biolink:NamedThing	syncytium formation by mitosis without cytokinesis	The formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by one or more rounds of nuclear division without cytokinesis.	tmpzr1t_l9r_go_relaxed.owl	syncytium formation by mitosis without cell division													biological_process											owl:Class	
GO:0010515	biolink:NamedThing	negative regulation of induction of conjugation with cellular fusion	Any process that stops, prevents, or reduces the frequency or rate of initiation of conjugation with cellular fusion.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0015280	biolink:NamedThing	ligand-gated sodium channel activity	Enables the transmembrane transfer of a sodium ion by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts.	tmpzr1t_l9r_go_relaxed.owl	ASIC activity|amiloride-sensitive sodium channel activity|epithelial sodium channel|acid-sensing ion channel activity				Reactome:R-HSA-2672334									molecular_function											owl:Class	
GO:0034172	biolink:NamedThing	negative regulation of toll-like receptor 11 signaling pathway	Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 11 signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of toll-like receptor 11 signalling pathway|negative regulation of TLR11 signaling pathway													biological_process											owl:Class	
GO:1990443	biolink:NamedThing	peptidyl-threonine autophosphorylation	The phosphorylation by a protein of one or more of its own threonine amino acid residues, or a threonine residue on an identical protein.	tmpzr1t_l9r_go_relaxed.owl								al	2014-08-02T15:08:41Z					biological_process											owl:Class	
GO:0048251	biolink:NamedThing	elastic fiber assembly	Assembly of the extracellular matrix fibers that enables the matrix to recoil after transient stretching.	tmpzr1t_l9r_go_relaxed.owl	elastin fibre assembly|elastin fiber assembly|elastic fibre assembly													biological_process											owl:Class	
GO:0030844	biolink:NamedThing	positive regulation of intermediate filament depolymerization	Any process that activates or increases the frequency, rate or extent of intermediate filament depolymerization.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of intermediate filament depolymerization|up regulation of intermediate filament depolymerization|stimulation of intermediate filament depolymerization|activation of intermediate filament depolymerization|positive regulation of intermediate filament polymerization and/or depolymerization|upregulation of intermediate filament depolymerization					Note that this term was split from 'positive regulation of intermediate filament polymerization and/or depolymerization ; GO:0045826' (sibling term 'positive regulation of intermediate filament polymerization ; GO:0030841').								biological_process											owl:Class	
GO:0043697	biolink:NamedThing	cell dedifferentiation	The process in which a specialized cell loses the structural or functional features that characterize it in the mature organism, or some other relatively stable phase of the organism's life history. Under certain conditions, these cells can revert back to the features of the stem cells that were their ancestors.	tmpzr1t_l9r_go_relaxed.owl						Note that this term should be used to annotate gene products involved in dedifferentiation that occurs as part of a normal process, such as regeneration. It should not be used for dedifferentiation that occurs in an abnormal or disease state such as cancer.								biological_process											owl:Class	
GO:0061036	biolink:NamedThing	positive regulation of cartilage development	Any process that increases the rate, frequency, or extent of cartilage development, the process whose specific outcome is the progression of the cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-02-09T03:41:35Z					biological_process											owl:Class	
GO:0010568	biolink:NamedThing	regulation of budding cell apical bud growth	Any process that modulates the frequency, rate or extent of growth at the tip of a bud, in a cell that reproduces by budding.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1900771	biolink:NamedThing	fumitremorgin B catabolic process	The chemical reactions and pathways resulting in the breakdown of fumitremorgin B.	tmpzr1t_l9r_go_relaxed.owl	Lanosulin degradation|Lanosulin catabolic process|Lanosulin breakdown|Lanosulin catabolism|fumitremorgin B catabolism|fumitremorgin B degradation|fumitremorgin B breakdown							di	2012-06-04T09:25:43Z					biological_process											owl:Class	
GO:1904697	biolink:NamedThing	regulation of acinar cell proliferation	Any process that modulates the frequency, rate or extent of acinar cell proliferation.	tmpzr1t_l9r_go_relaxed.owl	regulation of acinous cell proliferation|regulation of acinic cell proliferation							sl	2015-09-30T15:19:50Z					biological_process											owl:Class	
GO:0004084	biolink:NamedThing	branched-chain-amino-acid transaminase activity	Catalysis of the reaction: a branched-chain amino acid + 2-oxoglutarate = L-glutamate + a 2-oxocarboxylate derived from the branched-chain amino acid.	tmpzr1t_l9r_go_relaxed.owl	branched-chain aminotransferase activity|transaminase B activity|glutamate-branched-chain amino acid transaminase activity|L-branched chain amino acid aminotransferase activity|branched-chain-amino-acid:2-oxoglutarate aminotransferase activity|branched-chain amino acid-glutamate transaminase activity|branched-chain amino acid aminotransferase activity				EC:2.6.1.42|Reactome:R-HSA-70724|Reactome:R-HSA-70723|Reactome:R-HSA-508179|Reactome:R-HSA-508189									molecular_function											owl:Class	
GO:0102524	biolink:NamedThing	tRNAPhe (7-(3-amino-3-carboxypropyl)wyosine37-C2)-hydroxylase activity	Catalysis of the reaction: 2-oxoglutarate + O2 + 7-[(3S)-(3-amino-3-carboxypropyl)]-wyosine37 in tRNAPhe = succinate + carbon dioxide + 7-(2-hydroxy-3-amino-3-carboxypropyl)-wyosine37 in tRNAPhe.	tmpzr1t_l9r_go_relaxed.owl					RHEA:37899|EC:1.14.11.42|MetaCyc:RXN-14538									molecular_function											owl:Class	
GO:0045133	biolink:NamedThing	2,3-dihydroxybenzoate 3,4-dioxygenase activity	Catalysis of the reaction: 2,3-dihydroxybenzoate + O(2) = 2-hydroxy-3-(3-oxoprop-1-enyl)but-2-enedioate + H(+).	tmpzr1t_l9r_go_relaxed.owl	2,3-dihydroxybenzoic oxygenase activity|2,3-dihydroxybenzoate oxygenase activity|2,3-dihydroxybenzoate 1,2-dioxygenase activity|2,3-dihydroxybenzoate:oxygen 3,4-oxidoreductase (decyclizing)|o-pyrocatechuate oxygenase activity				RHEA:18477|MetaCyc:1.13.11.14-RXN|EC:1.13.11.14|KEGG_REACTION:R01507									molecular_function											owl:Class	
GO:1990383	biolink:NamedThing	cellular response to biotin starvation	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of biotin.	tmpzr1t_l9r_go_relaxed.owl								al	2014-05-21T10:06:58Z					biological_process											owl:Class	
GO:0015540	biolink:NamedThing	3-hydroxyphenyl propionate:proton symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: 3-hydroxyphenyl propionate(out) + H+(out) = 3-hydroxyphenyl propionate(in) + H+(in).	tmpzr1t_l9r_go_relaxed.owl	3-hydroxyphenyl propionate:hydrogen ion symporter activity|3-hydroxyphenyl propionate porter activity													molecular_function											owl:Class	
GO:0015551	biolink:NamedThing	3-hydroxyphenyl propanoate transmembrane transporter activity	Enables the transfer of 3-hydroxyphenyl propanoate from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	3-hydroxyphenyl propionate transmembrane transporter activity													molecular_function											owl:Class	
GO:0000098	biolink:NamedThing	sulfur amino acid catabolic process	The chemical reactions and pathways resulting in the breakdown of amino acids containing sulfur, comprising cysteine, methionine and selenocysteine.	tmpzr1t_l9r_go_relaxed.owl	sulfur amino acid degradation|sulfur amino acid breakdown|sulphur amino acid catabolic process|sulphur amino acid catabolism|sulfur amino acid catabolism													biological_process											owl:Class	
GO:0052130	biolink:NamedThing	negative aerotaxis	The directed movement of a motile cell or organism towards a lower concentration of environmental oxygen.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0045625	biolink:NamedThing	regulation of T-helper 1 cell differentiation	Any process that modulates the frequency, rate or extent of T-helper 1 cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	regulation of T-helper 1 cell development					Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.								biological_process											owl:Class	
GO:0140372	biolink:NamedThing	histone H3 ubiquitination	The modification of histone H3 by the addition of one or more ubiquitin groups.	tmpzr1t_l9r_go_relaxed.owl	histone H3 ubiquitylation							pg	2019-10-03T15:29:54Z					biological_process											owl:Class	
GO:0018765	biolink:NamedThing	2-hydroxy-6-oxohepta-2,4-dienoate hydrolase activity	Catalysis of the reaction: cis,cis-2-hydroxy-6-oxohept-2,4-dienoate + OH- = cis-2-hydroxypenta-2,4-dienoate + acetate.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:2-OH-6-OXOHEPTA-2-4-DIENOATE-HYDR-RXN|UM-BBD_reactionID:r0263|RHEA:59220									molecular_function											owl:Class	
GO:0060538	biolink:NamedThing	skeletal muscle organ development	The progression of a skeletal muscle organ over time from its initial formation to its mature state. A skeletal muscle organ includes the skeletal muscle tissue and its associated connective tissue.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-04-10T08:25:12Z					biological_process											owl:Class	
GO:1903342	biolink:NamedThing	negative regulation of meiotic DNA double-strand break formation	Any process that stops, prevents or reduces the frequency, rate or extent of meiotic DNA double-strand break formation.	tmpzr1t_l9r_go_relaxed.owl	down regulation of meiotic DNA double-strand break formation|inhibition of meiotic DNA double-strand break formation|downregulation of meiotic DNA double-strand break formation|down-regulation of meiotic DNA double-strand break formation							mcc	2014-08-18T21:32:03Z					biological_process											owl:Class	
GO:0003918	biolink:NamedThing	DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity	Catalysis of a DNA topological transformation by transiently cleaving a pair of complementary DNA strands to form a gate through which a second double-stranded DNA segment is passed, after which the severed strands in the first DNA segment are rejoined, driven by ATP hydrolysis. The enzyme changes the linking number in multiples of 2.	tmpzr1t_l9r_go_relaxed.owl	DNA topoisomerase II|DNA topoisomerase II activity|DNA topoisomerase IV activity|topoisomerase|type II DNA topoisomerase activity|topoisomerase II|deoxyribonucleate topoisomerase|deoxyribonucleic topoisomerase activity|DNA topoisomerase (ATP-hydrolysing)|DNA topoisomerase type II activity				MetaCyc:5.99.1.3-RXN|Wikipedia:Type_II_topoisomerase|EC:5.6.2.2							GO:0061505		molecular_function											owl:Class	
GO:1904187	biolink:NamedThing	regulation of transformation of host cell by virus	Any process that modulates the frequency, rate or extent of transformation of host cell by virus.	tmpzr1t_l9r_go_relaxed.owl	regulation of viral transformation|regulation of viral transformation of host cell							pga	2015-05-05T15:29:58Z					biological_process											owl:Class	
GO:0002143	biolink:NamedThing	tRNA wobble position uridine thiolation	The process in which a uridine residue at position 34 in the anticodon of a tRNA is post-transcriptionally thiolated at the C2 position. This process involves transfer of a sulfur from cysteine to position C2 by several steps.	tmpzr1t_l9r_go_relaxed.owl	wobble position s2U biosynthesis|tRNA wobble uridine thiolation					In E. coli, the first step of the reaction is reductive elimination of sulfur from L-cysteine by IscS cysteine desulfurase to form an enzyme-bound cysteine-persulfide intermediate. Then, five essential gene products, TusA, TusB, TusC, TusD and TusE, mediate a sulfur relay that delivers the terminal sulfur of persulfide from IscS to MnmA12. The last protein, MnmA catalyzes the transfer of the sulfur from IscS to an ATP activated U34 of the tRNA.		hjd	2009-05-06T05:05:40Z					biological_process											owl:Class	
GO:1905165	biolink:NamedThing	regulation of lysosomal protein catabolic process	Any process that modulates the frequency, rate or extent of lysosomal protein catabolic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of cellular protein degradation in lysosome|regulation of proteolysis within lysosome|regulation of cellular protein catabolism in lysosome|regulation of lysosomal protein degradation|regulation of cellular protein catabolic process in lysosome|regulation of cellular protein breakdown in lysosome|regulation of lysosomal protein catabolism|regulation of lysosomal proteolysis							bf	2016-04-26T12:10:01Z					biological_process											owl:Class	
GO:0016135	biolink:NamedThing	saponin biosynthetic process	The chemical reactions and pathways resulting in the formation of saponins, glycosides of plants in which the aglycan (sapogenin) group is a terpene or steroid and the sugar group is a glucose, a galactose, a pentose, a methylpentose or an oligosaccharide. Saponins are powerful surfactant agents and membrane active; they are, hence, toxic to animals on injection.	tmpzr1t_l9r_go_relaxed.owl	saponin anabolism|saponin biosynthesis|saponin formation|saponin synthesis													biological_process											owl:Class	
GO:0032023	biolink:NamedThing	trypsinogen activation	The proteolytic processing of trypsinogen to the active form, trypsin.	tmpzr1t_l9r_go_relaxed.owl	cleavage of trypsinogen to trypsin													biological_process											owl:Class	
GO:0102027	biolink:NamedThing	S-adenosylmethionine:2-demethylquinol-8 methyltransferase activity	Catalysis of the reaction: 2-demethylmenaquinol-8 + S-adenosyl-L-methionine <=> menaquinol-8 + H+ + S-adenosyl-L-homocysteine.	tmpzr1t_l9r_go_relaxed.owl					EC:2.1.1.163|MetaCyc:ADOMET-DMK-METHYLTRANSFER-RXN|RHEA:30063									molecular_function											owl:Class	
GO:0043983	biolink:NamedThing	histone H4-K12 acetylation	The modification of histone H4 by the addition of an acetyl group to a lysine residue at position 12 of the histone.	tmpzr1t_l9r_go_relaxed.owl	histone H4 acetylation at K12													biological_process											owl:Class	
GO:0038138	biolink:NamedThing	ERBB4-ERBB4 signaling pathway	A series of molecular signals initiated by binding of a ligand to the tyrosine kinase receptor ERBB4, followed by ligand-induced homodimerization of ERBB4 and transmission of the signal into the cell by the homodimeric ERBB4 complex. The pathway ends with regulation of a downstream cellular process, e.g. transcription.	tmpzr1t_l9r_go_relaxed.owl	ERBB4-ERBB4 signalling pathway|HER4-HER4 signaling pathway|ERBB4 homodimeric signaling pathway							bf	2012-03-30T11:41:05Z					biological_process											owl:Class	
GO:0018678	biolink:NamedThing	4-hydroxybenzoate 1-hydroxylase activity	Catalysis of the reaction: 4-hydroxybenzoate + NADPH + H+ + O2 = hydroquinone + NADP+ + H2O + CO2.	tmpzr1t_l9r_go_relaxed.owl	4-hydroxybenzoate 1-monooxygenase activity|4-hydroxybenzoate,NAD(P)H:oxygen oxidoreductase (1-hydroxylating, decarboxylating)				MetaCyc:1.14.13.64-RXN|EC:1.14.13.64|UM-BBD_reactionID:r0752									molecular_function											owl:Class	
GO:0120126	biolink:NamedThing	response to copper ion starvation	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of copper ion.	tmpzr1t_l9r_go_relaxed.owl								krc	2018-02-12T19:49:19Z					biological_process											owl:Class	
GO:0060027	biolink:NamedThing	convergent extension involved in gastrulation	The morphogenetic process in which an epithelium narrows along one axis and lengthens in a perpendicular axis usually resulting in the formation of the three primary germ layers, ectoderm, mesoderm and endoderm.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1902694	biolink:NamedThing	superoxide dismutase copper chaperone complex	A protein complex which is capable of superoxide dismutase copper chaperone activity.	tmpzr1t_l9r_go_relaxed.owl						An example of this is CCS1 in Saccharomyces cerevisiae S288c (UniProt symbol P40202) in PMID:10426947.		bhm	2014-02-18T11:13:45Z					cellular_component											owl:Class	
GO:1902695	biolink:NamedThing	metallochaperone complex	A protein complex which is capable of metallochaperone activity.	tmpzr1t_l9r_go_relaxed.owl								bhm	2014-02-18T11:34:40Z					cellular_component											owl:Class	
GO:0048057	biolink:NamedThing	R3/R4 development	The process whose specific outcome is the progression of the R3 and R4 pair of photoreceptors in the eye over time, from their formation to the mature structures. R3 and R4 are paired photoreceptors that contribute to the outer rhabdomeres. An example of this process is found in Drosophila melanogaster.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0086047	biolink:NamedThing	membrane depolarization during Purkinje myocyte cell action potential	The process in which Purkinje myocyte membrane potential changes in the depolarizing direction from the negative resting potential towards the positive membrane potential that will be the peak of the action potential.	tmpzr1t_l9r_go_relaxed.owl								dph	2011-11-16T10:54:47Z					biological_process											owl:Class	
GO:0042770	biolink:NamedThing	signal transduction in response to DNA damage	A cascade of processes induced by the detection of DNA damage within a cell.	tmpzr1t_l9r_go_relaxed.owl	response to DNA damage stimulus by intracellular signaling cascade|DNA damage response, signal transduction													biological_process											owl:Class	
GO:0098924	biolink:NamedThing	retrograde trans-synaptic signaling by nitric oxide	Cell-cell signaling from postsynapse to presynapse, across the synaptic cleft, mediated by nitric oxide.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0090306	biolink:NamedThing	meiotic spindle assembly	The aggregation, arrangement and bonding together of a set of components to form the spindle that contributes to the process of meiosis.	tmpzr1t_l9r_go_relaxed.owl	spindle assembly involved in meiosis	https://github.com/geneontology/go-ontology/issues/21349						tb	2010-04-09T11:21:56Z					biological_process											owl:Class	
GO:2000698	biolink:NamedThing	positive regulation of epithelial cell differentiation involved in kidney development	Any process that activates or increases the frequency, rate or extent of epithelial cell differentiation involved in kidney development.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-05-16T04:23:57Z					biological_process											owl:Class	
GO:0070368	biolink:NamedThing	positive regulation of hepatocyte differentiation	Any process that activates or increases the rate or extent of hepatocyte differentiation.	tmpzr1t_l9r_go_relaxed.owl	up regulation of hepatocyte differentiation|up-regulation of hepatocyte differentiation|positive regulation of liver cell differentiation|stimulation of hepatocyte differentiation|activation of hepatocyte differentiation|upregulation of hepatocyte differentiation													biological_process											owl:Class	
GO:0030627	biolink:NamedThing	pre-mRNA 5'-splice site binding	Binding to a pre-mRNA 5' splice site sequence.	tmpzr1t_l9r_go_relaxed.owl	pre-mRNA 5' splice site binding													molecular_function											owl:Class	
GO:1900046	biolink:NamedThing	regulation of hemostasis	Any process that modulates the frequency, rate or extent of hemostasis.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-01-19T03:23:38Z					biological_process											owl:Class	
GO:0047188	biolink:NamedThing	aromatic-hydroxylamine O-acetyltransferase activity	Catalysis of the reaction: N-hydroxy-4-aminobiphenyl + N-hydroxy-4-acetylaminonbiphenyl = N-acetoxy-4-aminobiphenyl + N-hydroxy-4-aminobiphenyl.	tmpzr1t_l9r_go_relaxed.owl	arylhydroxamic acyltransferase activity|N-hydroxy-2-acetylaminofluorene N-O acyltransferase activity|N-hydroxy-4-acetylaminobiphenyl:N-hydroxy-4-aminobiphenyl O-acetyltransferase activity|aromatic hydroxylamine acetyltransferase activity|arylhydroxamic acid N,O-acetyltransferase activity|arylhydroxamate acyltransferase activity|N,O-acetyltransferase activity				EC:2.3.1.56|MetaCyc:2.3.1.56-RXN|RHEA:20325									molecular_function											owl:Class	
GO:1905244	biolink:NamedThing	regulation of modification of synaptic structure	Any process that modulates the frequency, rate or extent of modification of synaptic structure.	tmpzr1t_l9r_go_relaxed.owl	regulation of synapse remodelling							dos	2016-06-09T09:43:40Z					biological_process											owl:Class	
GO:0005986	biolink:NamedThing	sucrose biosynthetic process	The chemical reactions and pathways resulting in the formation of sucrose, the disaccharide fructofuranosyl-glucopyranoside.	tmpzr1t_l9r_go_relaxed.owl	sucrose formation|sucrose biosynthesis|sucrose synthesis|sucrose anabolism				MetaCyc:SUCSYN-PWY									biological_process											owl:Class	
GO:0005985	biolink:NamedThing	sucrose metabolic process	The chemical reactions and pathways involving sucrose, the disaccharide fructofuranosyl-glucopyranoside.	tmpzr1t_l9r_go_relaxed.owl	sucrose metabolism													biological_process											owl:Class	
GO:2000033	biolink:NamedThing	regulation of seed dormancy process	Any process that modulates the frequency, rate or extent of seed dormancy process.	tmpzr1t_l9r_go_relaxed.owl	regulation of seed dormancy							tb	2010-08-05T11:33:13Z					biological_process											owl:Class	
GO:2000034	biolink:NamedThing	regulation of seed maturation	Any process that modulates the frequency, rate or extent of seed maturation.	tmpzr1t_l9r_go_relaxed.owl								tb	2010-08-05T11:33:33Z					biological_process											owl:Class	
GO:1902859	biolink:NamedThing	propionyl-CoA catabolic process	The chemical reactions and pathways resulting in the breakdown of propionyl-CoA.	tmpzr1t_l9r_go_relaxed.owl	propionyl-CoA degradation|propionyl-CoA catabolism|propionyl-CoA breakdown							tt	2014-04-03T03:10:23Z					biological_process											owl:Class	
GO:0030701	biolink:NamedThing	NAD+-dinitrogen-reductase ADP-D-ribosyltransferase activity	Catalysis of the reaction: NAD+ + [dinitrogen reductase] = nicotinamide + ADP-D-ribosyl-[dinitrogen reductase].	tmpzr1t_l9r_go_relaxed.owl	NAD--azoferredoxin (ADP-ribose)transferase activity|NAD+:[dinitrogen reductase] (ADP-D-ribosyl)transferase activity|ADP-ribosyltransferase activity|NAD-azoferredoxin (ADPribose)transferase activity|NAD-dinitrogen-reductase ADP-D-ribosyltransferase activity				EC:2.4.2.37|RHEA:18077|MetaCyc:2.4.2.37-RXN									molecular_function											owl:Class	
GO:1903038	biolink:NamedThing	negative regulation of leukocyte cell-cell adhesion	Any process that stops, prevents or reduces the frequency, rate or extent of leukocyte cell-cell adhesion.	tmpzr1t_l9r_go_relaxed.owl	inhibition of leukocyte cell-cell adhesion|downregulation of leukocyte adhesion|inhibition of leukocyte cell adhesion|inhibition of leukocyte adhesion|down regulation of leukocyte cell-cell adhesion|downregulation of leukocyte cell-cell adhesion|down regulation of leukocyte cell adhesion|down-regulation of leukocyte cell adhesion|negative regulation of leukocyte adhesion|down regulation of leukocyte adhesion|downregulation of leukocyte cell adhesion|down-regulation of leukocyte adhesion|negative regulation of leukocyte cell adhesion|down-regulation of leukocyte cell-cell adhesion					Exogenous expression of ASS1 or NOS3 in HUVECs enhances NO production and inhibits monocyte adhesion		rl	2014-05-19T15:30:05Z					biological_process											owl:Class	
GO:0009383	biolink:NamedThing	rRNA (cytosine-C5-)-methyltransferase activity	Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to cytosine to form 5-methylcytosine in small subunit ribosomal RNA.	tmpzr1t_l9r_go_relaxed.owl	rRNA (cytosine-C5-967)-methyltransferase activity|rRNA m5C967 methyltransferase activity				Reactome:R-HSA-6790944|Reactome:R-HSA-6793057									molecular_function											owl:Class	
GO:0016434	biolink:NamedThing	rRNA (cytosine) methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing methylcytosine.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0032357	biolink:NamedThing	oxidized purine DNA binding	Binding to a DNA region containing an oxidized purine residue.	tmpzr1t_l9r_go_relaxed.owl	oxidised purine DNA binding|oxidized purine nucleobase DNA binding|oxidized purine base DNA binding													molecular_function											owl:Class	
GO:0032356	biolink:NamedThing	oxidized DNA binding	Binding to a DNA region containing an oxidized residue.	tmpzr1t_l9r_go_relaxed.owl	oxidised DNA binding													molecular_function											owl:Class	
GO:0047448	biolink:NamedThing	5-dehydro-4-deoxyglucarate dehydratase activity	Catalysis of the reaction: 5-dehydro-4-deoxy-D-glucarate + H(+) = 2,5-dioxopentanoate + CO(2) + H(2)O.	tmpzr1t_l9r_go_relaxed.owl	5-keto-4-deoxy-glucarate dehydratase activity|deoxyketoglucarate dehydratase activity|5-dehydro-4-deoxy-D-glucarate hydro-lyase (decarboxylating; 2,5-dioxopentanoate-forming)|5-dehydro-4-deoxy-D-glucarate hydro-lyase (decarboxylating)|D-4-deoxy-5-ketoglucarate hydro-lyase activity				KEGG_REACTION:R02279|RHEA:24608|EC:4.2.1.41|MetaCyc:4.2.1.41-RXN									molecular_function											owl:Class	
GO:0010989	biolink:NamedThing	negative regulation of low-density lipoprotein particle clearance	Any process that decreases the rate, frequency or extent of low-density lipoprotein particle clearance. Low-density lipoprotein particle clearance is the process in which a low-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-06-01T12:15:07Z					biological_process											owl:Class	
GO:0047230	biolink:NamedThing	flavonol-3-O-glucoside L-rhamnosyltransferase activity	Catalysis of the reaction: flavonol 3-O-D-glucoside + UDP-L-rhamnose = flavonol 3-O-L-rhamnosylglucoside + UDP.	tmpzr1t_l9r_go_relaxed.owl	uridine diphosphorhamnose-flavonol 3-O-glucoside rhamnosyltransferase activity|UDP-rhamnose:flavonol 3-O-glucoside rhamnosyltransferase activity|UDP-L-rhamnose:flavonol-3-O-D-glucoside 6''-O-L-rhamnosyltransferase activity				EC:2.4.1.159|RHEA:22528|MetaCyc:2.4.1.159-RXN									molecular_function											owl:Class	
GO:1901079	biolink:NamedThing	positive regulation of relaxation of muscle	Any process that activates or increases the frequency, rate or extent of relaxation of muscle.	tmpzr1t_l9r_go_relaxed.owl	upregulation of relaxation of muscle|up-regulation of relaxation of muscle|up regulation of relaxation of muscle|activation of relaxation of muscle							jl	2012-07-04T10:45:02Z					biological_process											owl:Class	
GO:0110125	biolink:NamedThing	negative regulation of myotube cell migration	Any process that stops, prevents, or reduces the frequency, rate or extent of myotube cell migration.	tmpzr1t_l9r_go_relaxed.owl								kmv	2018-08-22T21:12:47Z					biological_process											owl:Class	
GO:0045295	biolink:NamedThing	gamma-catenin binding	Binding to catenin complex gamma subunit.	tmpzr1t_l9r_go_relaxed.owl	plakoglobin binding													molecular_function											owl:Class	
GO:0010013	biolink:NamedThing	N-1-naphthylphthalamic acid binding	Binding to N-1-naphthylphthalamic acid, an auxin transport inhibitor.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0043991	biolink:NamedThing	histone H2B-S14 phosphorylation	The modification of histone H2B by the addition of an phosphate group to a serine residue at position 14 of the histone.	tmpzr1t_l9r_go_relaxed.owl	histone H2B phosphorylation at S14|histone H2BS14 phosphorylation													biological_process											owl:Class	
GO:0075037	biolink:NamedThing	positive regulation of appressorium maturation	Any process that activates or increases the frequency, rate or extent of symbiont appressorium maturation.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of appressorium maturation on or near host|positive regulation maturation of appressorium on or near host													biological_process											owl:Class	
GO:0002096	biolink:NamedThing	polkadots	A punctate, filamentous structure composed of Bcl10 that appears in the cytoplasm of T-cells shortly after T-cell receptor stimulation. Polkadots stands for Punctate Oligomeric Killing and Activating DOmains Transducing Signals.	tmpzr1t_l9r_go_relaxed.owl						Note that polkadots also contains some amount of MALT1. Interaction with MALT1 is required for formation of the polkadots.								cellular_component											owl:Class	
GO:0018416	biolink:NamedThing	nickel incorporation into iron-sulfur cluster via tris-L-cysteinyl L-cysteine persulfido bis-L-glutamato L-histidino nickel triiron disulfide trioxide	The incorporation of nickel into a 3Fe-2S complex by tris-L-cysteinyl L-cysteine persulfido bis-L-glutamato L-histidino nickel triiron disulfide trioxide.	tmpzr1t_l9r_go_relaxed.owl	nickel incorporation into iron-sulphur cluster via tris-L-cysteinyl L-cysteine persulphido bis-L-glutamato L-histidino nickel triiron disulphide trioxide				RESID:AA0292									biological_process											owl:Class	
GO:0061671	biolink:NamedThing	Cbp3p-Cbp6 complex	A protein complex located at the mitochondrial ribosome tunnel exit that is involved in efficient translation and protein complex assembly.	tmpzr1t_l9r_go_relaxed.owl								dph	2014-11-18T15:08:30Z					cellular_component											owl:Class	
GO:0004595	biolink:NamedThing	pantetheine-phosphate adenylyltransferase activity	Catalysis of the reaction: ATP + pantetheine 4'-phosphate = 3'-dephospho-CoA + diphosphate.	tmpzr1t_l9r_go_relaxed.owl	ATP:pantetheine-4'-phosphate adenylyltransferase activity|dephospho-coenzyme A pyrophosphorylase activity|PPAT activity|ATP:pantetheine-phosphate adenylyltransferase activity|dephospho-CoA diphosphorylase activity|phosphopantetheine adenylyltransferase activity|3'-dephospho-CoA pyrophosphorylase activity|dephospho-CoA pyrophosphorylase activity|pantetheine phosphate adenylyltransferase activity				EC:2.7.7.3|Reactome:R-HSA-196754|MetaCyc:PANTEPADENYLYLTRAN-RXN|RHEA:19801|KEGG_REACTION:R03035									molecular_function											owl:Class	
GO:0098658	biolink:NamedThing	inorganic anion import across plasma membrane	The directed movement of inorganic anions from outside of a cell, across the plasma membrane and into the cytosol.	tmpzr1t_l9r_go_relaxed.owl	inorganic anion import into cell													biological_process											owl:Class	
GO:1902251	biolink:NamedThing	negative regulation of erythrocyte apoptotic process	Any process that stops, prevents or reduces the frequency, rate or extent of erythrocyte apoptotic process.	tmpzr1t_l9r_go_relaxed.owl	inhibition of RBC apoptotic process|down regulation of erythrocyte apoptotic process|downregulation of erythrocyte apoptosis|down regulation of red blood cell apoptosis|inhibition of erythrocyte apoptosis|down regulation of RBC apoptotic process|inhibition of erythrocyte apoptotic process|downregulation of RBC apoptotic process|downregulation of red blood cell apoptotic process|down-regulation of red blood cell apoptotic process|negative regulation of red blood cell apoptotic process|down-regulation of erythrocyte apoptotic process|inhibition of red blood cell apoptosis|inhibition of red blood cell apoptotic process|downregulation of red blood cell apoptosis|negative regulation of erythrocyte apoptosis|down regulation of erythrocyte apoptosis|negative regulation of RBC apoptosis|negative regulation of red blood cell apoptosis|down-regulation of red blood cell apoptosis|down-regulation of RBC apoptotic process|inhibition of RBC apoptosis|down-regulation of RBC apoptosis|downregulation of RBC apoptosis|down regulation of red blood cell apoptotic process|down-regulation of erythrocyte apoptosis|down regulation of RBC apoptosis|negative regulation of RBC apoptotic process|downregulation of erythrocyte apoptotic process							rl	2013-06-20T19:30:59Z					biological_process											owl:Class	
GO:1905503	biolink:NamedThing	regulation of motile cilium assembly	Any process that modulates the frequency, rate or extent of motile cilium assembly.	tmpzr1t_l9r_go_relaxed.owl	regulation of nodal cilium formation|regulation of motile primary cilia assembly|regulation of motile primary cilium assembly|regulation of nodal cilium assembly|regulation of motile primary cilium formation|regulation of motile primary cilia formation							krc	2016-09-27T18:27:47Z					biological_process											owl:Class	
GO:0042250	biolink:NamedThing	maintenance of polarity of embryonic epithelium	The maintenance of an established polarized embryonic epithelial sheet.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0016332	biolink:NamedThing	establishment or maintenance of polarity of embryonic epithelium	Any cellular process that results in the specification, formation or maintenance of anisotropic intracellular organization of epithelial cells in an embryo.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0046880	biolink:NamedThing	regulation of follicle-stimulating hormone secretion	Any process that modulates the frequency, rate or extent of the regulated release of follicle-stimulating hormone.	tmpzr1t_l9r_go_relaxed.owl	regulation of FSH secretion|regulation of follicle stimulating hormone secretion													biological_process											owl:Class	
GO:0050458	biolink:NamedThing	decylhomocitrate synthase activity	Catalysis of the reaction: 2-oxoglutarate + H(2)O + lauroyl-CoA = (3S,4S)-3-hydroxytetradecane-1,3,4-tricarboxylate + CoA + H(+).	tmpzr1t_l9r_go_relaxed.owl	dodecanoyl-CoA:2-oxoglutarate C-dodecanoyltransferase (thioester-hydrolysing, 1-carboxyundecyl-forming)|2-decylhomocitrate synthase activity|3-hydroxytetradecane-1,3,4-tricarboxylate 2-oxoglutarate-lyase (CoA-acylating)|3-hydroxytetradecane-1,3,4-tricarboxylate 2-oxoglutarate-lyase (CoA- acylating) activity				MetaCyc:DECYLHOMOCITRATE-SYNTHASE-RXN|EC:2.3.3.4|RHEA:10364|KEGG_REACTION:R03859									molecular_function											owl:Class	
GO:0019278	biolink:NamedThing	UDP-N-acetylgalactosamine catabolic process	The chemical reactions and pathways resulting in the breakdown of UDP-N-acetylgalactosamine, a substance composed of N-acetylgalactosamine, a common structural unit of oligosaccharides, in glycosidic linkage with uridine diphosphate.	tmpzr1t_l9r_go_relaxed.owl	UDP-N-acetylgalactosamine breakdown|UDP-N-acetylgalactosamine catabolism|UDP-N-acetylgalactosamine degradation													biological_process											owl:Class	
GO:1903279	biolink:NamedThing	regulation of calcium:sodium antiporter activity	Any process that modulates the frequency, rate or extent of calcium:sodium antiporter activity.	tmpzr1t_l9r_go_relaxed.owl	regulation of sodium:calcium exchange|regulation of sodium/calcium exchanger|regulation of mitochondrial sodium/calcium ion exchange							rl	2014-08-11T12:53:30Z					biological_process											owl:Class	
GO:0034167	biolink:NamedThing	regulation of toll-like receptor 10 signaling pathway	Any process that modulates the frequency, rate, or extent of toll-like receptor 10 signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	regulation of TLR10 signaling pathway|regulation of toll-like receptor 10 signalling pathway													biological_process											owl:Class	
GO:1902762	biolink:NamedThing	regulation of embryonic skeletal joint development	Any process that modulates the frequency, rate or extent of embryonic skeletal joint development.	tmpzr1t_l9r_go_relaxed.owl								mr	2014-03-07T17:46:01Z					biological_process											owl:Class	
GO:0035374	biolink:NamedThing	chondroitin sulfate binding	Binding to chondroitin sulfate, a glycosaminoglycan made up of two alternating monosaccharides: D-glucuronic acid (GlcA) and N-acetyl-D-galactosamine (GalNAc).	tmpzr1t_l9r_go_relaxed.owl								bf	2010-03-12T10:25:34Z					molecular_function											owl:Class	
GO:0001974	biolink:NamedThing	blood vessel remodeling	The reorganization or renovation of existing blood vessels.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1905611	biolink:NamedThing	negative regulation of mRNA cap binding	Any process that stops, prevents or reduces the frequency, rate or extent of mRNA cap binding.	tmpzr1t_l9r_go_relaxed.owl	downregulation of mRNA cap binding|inhibition of mRNA cap binding|down regulation of mRNA cap binding|down-regulation of mRNA cap binding							bc	2016-10-28T11:27:36Z					biological_process											owl:Class	
GO:0061123	biolink:NamedThing	negative regulation of positive chemotaxis to cAMP	Any process that decreases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-05-17T08:27:20Z					biological_process											owl:Class	
GO:1904095	biolink:NamedThing	negative regulation of endosperm development	Any process that stops, prevents or reduces the frequency, rate or extent of endosperm development.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of endosperm development|inhibition of endosperm development|downregulation of endosperm development|down regulation of endosperm development							tb	2015-03-26T22:07:25Z					biological_process											owl:Class	
GO:0015937	biolink:NamedThing	coenzyme A biosynthetic process	The chemical reactions and pathways resulting in the formation of coenzyme A, 3'-phosphoadenosine-(5')diphospho(4')pantatheine, an acyl carrier in many acylation and acyl-transfer reactions in which the intermediate is a thiol ester.	tmpzr1t_l9r_go_relaxed.owl	coenzyme A anabolism|coenzyme A biosynthesis|CoA biosynthesis|coenzyme A synthesis|coenzyme A formation				MetaCyc:PWY-4221|MetaCyc:PANTOSYN-PWY|MetaCyc:COA-PWY							GO:0006764		biological_process											owl:Class	
GO:0031689	biolink:NamedThing	A3 adenosine receptor binding	Binding to an A3 adenosine receptor.	tmpzr1t_l9r_go_relaxed.owl	A3 adenosine receptor ligand													molecular_function											owl:Class	
GO:0031685	biolink:NamedThing	adenosine receptor binding	Binding to an adenosine receptor.	tmpzr1t_l9r_go_relaxed.owl	adenosine receptor ligand													molecular_function											owl:Class	
GO:0009944	biolink:NamedThing	polarity specification of adaxial/abaxial axis	The process resulting in the establishment of polarity along the adaxial/abaxial axis. Adaxial refers to being situated toward an axis of an anatomical structure. Abaxial refers to being situated away from an axis of an anatomical structure.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0038048	biolink:NamedThing	dynorphin receptor activity	Combining with a dynorphin peptide, and transmitting the signal across the membrane by activating an associated G-protein. Dynorphin is any opioid peptide that is generated by cleavage of the precursor protein prodynorphin.	tmpzr1t_l9r_go_relaxed.owl	kappa-opioid receptor activity							bf	2011-11-14T01:48:02Z					molecular_function											owl:Class	
GO:0006533	biolink:NamedThing	aspartate catabolic process	The chemical reactions and pathways resulting in the breakdown of aspartate, the anion derived from aspartic acid, 2-aminobutanedioic acid.	tmpzr1t_l9r_go_relaxed.owl	aspartate degradation|aspartate breakdown|aspartate catabolism													biological_process											owl:Class	
GO:0042836	biolink:NamedThing	D-glucarate metabolic process	The chemical reactions and pathways involving D-glucarate, the D-enantiomer of glucarate. D-glucarate is derived from either D-glucose or L-gulose.	tmpzr1t_l9r_go_relaxed.owl	saccharate metabolic process|D-glucarate metabolism|saccharate metabolism													biological_process											owl:Class	
GO:0033094	biolink:NamedThing	butane-1,4-diamine:2-oxoglutarate aminotransferase activity	Catalysis of the reaction: putrescine + 2-oxoglutarate = L-glutamate + 1-pyrroline + H2O.	tmpzr1t_l9r_go_relaxed.owl	PAT activity|YgjG|putrescine transaminase activity|putrescine:alpha-ketoglutarate aminotransferase activity|putrescine-alpha-ketoglutarate transaminase activity|putrescine aminotransferase activity|putrescine:2-oxoglutarate aminotransferase activity				EC:2.6.1.82|MetaCyc:2.6.1.82-RXN|RHEA:12268									molecular_function											owl:Class	
GO:1905167	biolink:NamedThing	positive regulation of lysosomal protein catabolic process	Any process that activates or increases the frequency, rate or extent of lysosomal protein catabolic process.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of cellular protein breakdown in lysosome|up regulation of proteolysis within lysosome|upregulation of proteolysis within lysosome|up regulation of lysosomal proteolysis|up regulation of cellular protein catabolism in lysosome|up-regulation of proteolysis within lysosome|activation of lysosomal protein catabolic process|activation of lysosomal protein catabolism|up-regulation of lysosomal protein catabolic process|positive regulation of cellular protein catabolic process in lysosome|activation of proteolysis within lysosome|upregulation of lysosomal proteolysis|up-regulation of cellular protein degradation in lysosome|upregulation of cellular protein breakdown in lysosome|up-regulation of cellular protein catabolism in lysosome|up-regulation of lysosomal proteolysis|positive regulation of lysosomal protein degradation|up-regulation of cellular protein catabolic process in lysosome|upregulation of cellular protein catabolism in lysosome|positive regulation of lysosomal protein catabolism|up regulation of cellular protein breakdown in lysosome|upregulation of cellular protein degradation in lysosome|up regulation of cellular protein catabolic process in lysosome|upregulation of cellular protein catabolic process in lysosome|up regulation of lysosomal protein degradation|positive regulation of proteolysis within lysosome|up-regulation of lysosomal protein catabolism|positive regulation of cellular protein degradation in lysosome|positive regulation of lysosomal proteolysis|up regulation of lysosomal protein catabolic process|up regulation of cellular protein degradation in lysosome|upregulation of lysosomal protein catabolism|up-regulation of cellular protein breakdown in lysosome|up-regulation of lysosomal protein degradation|positive regulation of cellular protein catabolism in lysosome|activation of cellular protein degradation in lysosome|activation of lysosomal protein degradation|up regulation of lysosomal protein catabolism|activation of cellular protein catabolic process in lysosome|upregulation of lysosomal protein degradation|activation of cellular protein breakdown in lysosome|upregulation of lysosomal protein catabolic process|activation of lysosomal proteolysis|activation of cellular protein catabolism in lysosome							bf	2016-04-26T12:10:19Z					biological_process											owl:Class	
GO:1990785	biolink:NamedThing	response to water-immersion restraint stress	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of water immersion while being held immobile.	tmpzr1t_l9r_go_relaxed.owl	response to immobilization stress combined with water immersion							sl	2015-06-24T18:27:28Z					biological_process											owl:Class	
GO:0035902	biolink:NamedThing	response to immobilization stress	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of being rendered immobile.	tmpzr1t_l9r_go_relaxed.owl	response to immobilisation stress|response to restraint stress							bf	2011-06-22T09:45:50Z					biological_process											owl:Class	
GO:0044381	biolink:NamedThing	glucose import in response to insulin stimulus	The directed movement of the hexose monosaccharide glucose into a cell as a result of an insulin stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular glucose import in response to insulin stimulus							jl	2011-12-08T02:44:01Z					biological_process											owl:Class	
GO:0070748	biolink:NamedThing	interleukin-35 receptor binding	Binding to an interleukin-35 receptor.	tmpzr1t_l9r_go_relaxed.owl	IL-35|interleukin-35 receptor ligand							mah	2009-06-23T01:21:54Z					molecular_function											owl:Class	
GO:0071623	biolink:NamedThing	negative regulation of granulocyte chemotaxis	Any process that decreases the rate, frequency or extent of granulocyte chemotaxis. Granulocyte chemotaxis is the movement of a granulocyte in response to an external stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-02-09T04:13:19Z					biological_process											owl:Class	
GO:0046314	biolink:NamedThing	phosphocreatine biosynthetic process	The chemical reactions and pathways resulting in the formation of phosphocreatine, a phosphagen of creatine which is synthesized and broken down by creatine phosphokinase.	tmpzr1t_l9r_go_relaxed.owl	phosphocreatine biosynthesis|phosphocreatine formation|phosphocreatine synthesis|phosphocreatine anabolism													biological_process											owl:Class	
GO:0042396	biolink:NamedThing	phosphagen biosynthetic process	The chemical reactions and pathways resulting in the formation of phosphagen, any of a group of guanidine phosphates that occur in muscle and can be used to regenerate ATP from ADP during muscular contraction.	tmpzr1t_l9r_go_relaxed.owl	phosphagen anabolism|phosphagen biosynthesis|phosphagen synthesis|phosphagen formation													biological_process											owl:Class	
GO:0036308	biolink:NamedThing	16S rRNA (guanine(1516)-N(2))-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + guanosine(1516) in 16S rRNA = N(2)-methylguanosine(1516) in 16S rRNA + S-adenosyl-L-homocysteine.	tmpzr1t_l9r_go_relaxed.owl								bf	2012-08-08T14:17:44Z					molecular_function											owl:Class	
GO:0044469	biolink:NamedThing	envenomation resulting in positive regulation of blood coagulation in other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant activation, maintenance or an increase in the frequency, rate or extent of blood coagulation in the bitten organism.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-01-19T01:29:09Z					biological_process											owl:Class	
GO:0019631	biolink:NamedThing	quinate catabolic process	The chemical reactions and pathways resulting in the breakdown of quinate, the anion of quinic acid.	tmpzr1t_l9r_go_relaxed.owl	quinate catabolism|quinic acid catabolic process|quinate degradation|quinic acid catabolism|quinate breakdown				MetaCyc:QUINATEDEG-PWY									biological_process											owl:Class	
GO:0019630	biolink:NamedThing	quinate metabolic process	The chemical reactions and pathways involving quinate, the anion of quinic acid. The acid occurs commonly in plants, either free or as esters, and is used as a medicine.	tmpzr1t_l9r_go_relaxed.owl	quinic acid metabolic process|quinate metabolism|quinic acid metabolism													biological_process											owl:Class	
GO:0021726	biolink:NamedThing	lateral reticular nucleus development	The process whose specific outcome is the progression of the lateral reticular nucleus over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0019490	biolink:NamedThing	2-aminobenzenesulfonate desulfonation	The removal of the sulfonate group from 2-aminobenzenesulfonate, an aromatic sulfonate used in organic synthesis and in the manufacture of various dyes and medicines.	tmpzr1t_l9r_go_relaxed.owl	2-aminobenzenesulphonate desulphonation				MetaCyc:2ASDEG-PWY									biological_process											owl:Class	
GO:0102347	biolink:NamedThing	trans-arachidon-2-enoyl-CoA reductase activity	Catalysis of the reaction: icosanoyl-CoA(4-) + NADP(3-) <=> trans-2-icosenoyl-CoA(4-) + NADPH(4-) + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-13306									molecular_function											owl:Class	
GO:0016716	biolink:NamedThing	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen	Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from each of two donors, and one atom of oxygen is incorporated into one donor.	tmpzr1t_l9r_go_relaxed.owl					EC:1.14.18.-									molecular_function											owl:Class	
GO:0045428	biolink:NamedThing	regulation of nitric oxide biosynthetic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nitric oxide.	tmpzr1t_l9r_go_relaxed.owl	regulation of nitric oxide synthesis|regulation of nitric oxide anabolism|regulation of nitric oxide biosynthesis|regulation of nitric oxide formation													biological_process											owl:Class	
GO:0034784	biolink:NamedThing	pivalyl-CoA mutase activity	Catalysis of the reaction: pivalyl-CoA = 3-methylbutyryl-CoA.	tmpzr1t_l9r_go_relaxed.owl					EC:5.4.99.-|UM-BBD_reactionID:r1033									molecular_function											owl:Class	
GO:0046011	biolink:NamedThing	regulation of oskar mRNA translation	Any process that modulates the frequency, rate or extent of oskar mRNA translation. To ensure the localization of Oskar protein at the posterior pole of the oocyte, translation of oskar mRNA is repressed during its transport to the posterior pole and activated upon localization of the mRNA at the posterior cortex.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0008288	biolink:NamedThing	boss receptor activity	Combining with a protein bride of sevenless (boss) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: ATP + a protein-L-tyrosine = ADP + a protein-L-tyrosine phosphate.	tmpzr1t_l9r_go_relaxed.owl	sevenless receptor activity													molecular_function											owl:Class	
GO:0032435	biolink:NamedThing	negative regulation of proteasomal ubiquitin-dependent protein catabolic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of proteasomal ubiquitin-dependent protein catabolic process|inhibition of proteasomal ubiquitin-dependent protein catabolic process|down regulation of proteasomal ubiquitin-dependent protein catabolic process|downregulation of proteasomal ubiquitin-dependent protein catabolic process													biological_process											owl:Class	
GO:0071634	biolink:NamedThing	regulation of transforming growth factor beta production	Any process that modulates the frequency, rate, or extent of production of transforming growth factor-beta.	tmpzr1t_l9r_go_relaxed.owl	regulation of TGFB production|regulation of TGF-beta production|regulation of TGFbeta production|regulation of TGF-B production|regulation of transforming growth factor-beta secretion|regulation of transforming growth factor-beta production							mah	2010-02-12T10:33:07Z			GO:2001201		biological_process											owl:Class	
GO:0033575	biolink:NamedThing	protein glycosylation at cell surface	The addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid at the surface of a cell.	tmpzr1t_l9r_go_relaxed.owl	protein amino acid glycosylation at cell surface													biological_process											owl:Class	
GO:0009977	biolink:NamedThing	proton motive force dependent protein transmembrane transporter activity	Catalysis of the transfer of proteins from one side of a membrane to the other. Transportation is dependent on pH gradient across the membrane.	tmpzr1t_l9r_go_relaxed.owl	pH-dependent protein transporter activity|arginine targeting transmembrane transporter activity|twin-arginine targeting transmembrane transporter activity|delta-pH-dependent protein transporter activity											GO:0015557		molecular_function											owl:Class	
GO:1901065	biolink:NamedThing	syringal lignin catabolic process	The chemical reactions and pathways resulting in the breakdown of syringal lignin.	tmpzr1t_l9r_go_relaxed.owl	syringal lignin catabolism|syringal lignin breakdown|S-lignin catabolic process|syringal lignin degradation							tt	2012-06-29T03:48:33Z					biological_process											owl:Class	
GO:0035186	biolink:NamedThing	syncytial blastoderm mitotic cell cycle	Mitotic division cycles 10 to 13 of the insect embryo. This is the second phase of the syncytial period where nuclei divide in a common cytoplasm without cytokinesis. The majority of migrating nuclei reach the embryo surface during cycle 10, after which they divide less synchronously than before, and the syncytial blastoderm cycles lengthen progressively.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0120134	biolink:NamedThing	proximal portion of axoneme	The portion of the axoneme that is close to the base of the cilium.	tmpzr1t_l9r_go_relaxed.owl	proximal part of axoneme							krc	2018-03-10T01:41:06Z					cellular_component											owl:Class	
GO:1905849	biolink:NamedThing	negative regulation of forward locomotion	Any process that stops, prevents or reduces the frequency, rate or extent of forward locomotion.	tmpzr1t_l9r_go_relaxed.owl	down regulation of forward locomotion|downregulation of forward locomotion|inhibition of forward locomotion|down-regulation of forward locomotion							rz	2017-01-23T11:03:55Z					biological_process											owl:Class	
GO:0055012	biolink:NamedThing	ventricular cardiac muscle cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a ventricular cardiac muscle cell. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction. The ventricle is the part of the heart that pumps blood out of the organ.	tmpzr1t_l9r_go_relaxed.owl	ventricular cardiomyocyte differentiation|ventricular heart muscle cell differentiation													biological_process											owl:Class	
GO:0031481	biolink:NamedThing	myosin XI complex	A myosin complex containing a dimer of class XI myosin heavy chains and associated light chains. Myosin XI heavy chain sizes are similar in molecular structure to the class V myosins with 5 to 6 IQ motifs and tail regions with predicted coiled coil domains (forming dimeric molecules) and large C-terminal regions.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0032053	biolink:NamedThing	ciliary basal body organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a ciliary basal body, a short cylindrical array of microtubules and associated proteins found at the base of a eukaryotic cilium (also called flagellum).	tmpzr1t_l9r_go_relaxed.owl	microtubule basal body organisation|microtubule basal body organization and biogenesis|microtubule basal body organization													biological_process											owl:Class	
GO:0072315	biolink:NamedThing	metanephric glomerular epithelial cell fate commitment	The process in which the developmental fate of a cell becomes restricted such that it will develop into a metanephric glomerular epithelial cell. Metanephric glomerular epithelial cells are specialized epithelial cells that form part of the metanephric glomerulus; there are two types, metanephric glomerular parietal epithelial cells and metanephric glomerular visceral epithelial cells.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-04-09T07:03:50Z					biological_process											owl:Class	
GO:0055017	biolink:NamedThing	cardiac muscle tissue growth	The increase in size or mass of a cardiac muscle, where the increase in size or mass has the specific outcome of the progression of the organism over time from one condition to another.	tmpzr1t_l9r_go_relaxed.owl	heart muscle growth													biological_process											owl:Class	
GO:1905372	biolink:NamedThing	ceramide phosphoethanolamine catabolic process	The chemical reactions and pathways resulting in the breakdown of ceramide phosphoethanolamine.	tmpzr1t_l9r_go_relaxed.owl	ceramide phosphoethanolamine degradation|ceramide phosphoethanolamine breakdown|ceramide phosphoethanolamine catabolism							hjd	2016-08-16T17:11:04Z					biological_process											owl:Class	
GO:1905371	biolink:NamedThing	ceramide phosphoethanolamine metabolic process	The chemical reactions and pathways involving ceramide phosphoethanolamine.	tmpzr1t_l9r_go_relaxed.owl	ceramide phosphoethanolamine metabolism							hjd	2016-08-16T17:10:56Z					biological_process											owl:Class	
GO:0018629	biolink:NamedThing	2-hydroxyquinoline 5,6-dioxygenase activity	Catalysis of the reaction: quinolin-2-ol + NADH + H+ + O2 = 2,5,6-trihydroxy-5,6-dihydroquinoline + NAD+.	tmpzr1t_l9r_go_relaxed.owl	2-oxo-1,2-dihydroquinoline 5,6-dioxygenase activity|quinolin-2-ol,NADH:oxygen oxidoreductase (5,6-hydroxylating)|quinolin-2(1H)-one 5,6-dioxygenase activity|quinolin-2-ol 5,6-dioxygenase activity				UM-BBD_reactionID:r0052|MetaCyc:1.14.12.16-RXN|RHEA:10976|EC:1.14.12.16									molecular_function											owl:Class	
GO:0046830	biolink:NamedThing	positive regulation of RNA import into nucleus	Any process that activates or increases the frequency, rate or extent of movement of RNA from the cytoplasm into the nucleus.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of RNA-nucleus import|upregulation of RNA import into nucleus|up-regulation of RNA import into nucleus|up regulation of RNA import into nucleus|positive regulation of RNA import into cell nucleus|stimulation of RNA import into nucleus|activation of RNA import into nucleus|positive regulation of RNA transport from cytoplasm to nucleus													biological_process											owl:Class	
GO:0097170	biolink:NamedThing	ADP-L-glycero-beta-D-manno-heptose metabolic process	The chemical reactions and pathways involving ADP-L-glycero-beta-D-manno-heptose, an ADP-L-glycero-D-manno-heptose having beta-configuration at the anomeric centre of the heptose. ADP-L-glycero-beta-D-manno-heptose (also called ADP-L-beta-D-heptose or ADP-L-glycero-D-manno-heptose) is a nucleotide-sugar precursor of the inner core lipopolysaccharide (LPS) from D-glycero-beta-D-manno-heptose 7-phosphate.	tmpzr1t_l9r_go_relaxed.owl	ADP-L-glycero-beta-D-manno-heptose metabolism							pr	2011-10-03T09:12:58Z					biological_process											owl:Class	
GO:2000644	biolink:NamedThing	regulation of receptor catabolic process	Any process that modulates the frequency, rate or extent of receptor catabolic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of receptor breakdown|regulation of receptor degradation|regulation of receptor catabolism							vk	2011-04-21T11:20:18Z					biological_process											owl:Class	
GO:0098573	biolink:NamedThing	intrinsic component of mitochondrial membrane	The component of the mitochondrial membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.	tmpzr1t_l9r_go_relaxed.owl	intrinsic to mitochondrial membrane													cellular_component											owl:Class	
GO:0031522	biolink:NamedThing	cell envelope Sec protein transport complex	A transmembrane protein complex involved in the translocation of proteins across the cytoplasmic membrane. In Gram-negative bacteria, Sec-translocated proteins are subsequently secreted via the type II, IV, or V secretion systems. Sec complex components include SecA, D, E, F, G, Y and YajC.	tmpzr1t_l9r_go_relaxed.owl	Sec complex|plasma membrane Sec complex|Sec translocation complex|Sec secretion complex					Note that this term represents the protein complex involved in transport of proteins across the cytoplasmic membrane. For proteins involved in bacterial type II secretion across the outer membrane, consider annotating to 'type II protein secretion complex ; GO:0015628'. For proteins involved in Sec-complex dependent translocation into the eukaryotic endoplasmic reticulum, consider annotating to 'endoplasmic reticulum Sec complex ; GO:0031205'.								cellular_component											owl:Class	
GO:0090562	biolink:NamedThing	protein-N(PI)-phosphohistidine-N,N'-diacetylchitobiose phosphotransferase system transporter activity	Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + N,N'-diacetylchitobiose(out) = protein histidine + N,N'-diacetylchitobiose phosphate(in).	tmpzr1t_l9r_go_relaxed.owl								tb	2014-04-08T14:55:02Z					molecular_function											owl:Class	
GO:0046845	biolink:NamedThing	branched duct epithelial cell fate determination, open tracheal system	Allocation of a set number of cells to each primary branch in an open tracheal system, prior to the onset of cell migration. This establishes different domains of cells within the tracheal placode.	tmpzr1t_l9r_go_relaxed.owl	branch cell fate determination													biological_process											owl:Class	
GO:1904352	biolink:NamedThing	positive regulation of protein catabolic process in the vacuole	Any process that activates or increases the frequency, rate or extent of protein catabolic process in the vacuole.	tmpzr1t_l9r_go_relaxed.owl	up regulation of protein catabolic process in the vacuole|upregulation of vacuolar protein catabolic process|up-regulation of protein catabolic process in the vacuole|up-regulation of vacuolar protein catabolism|activation of vacuolar protein degradation|activation of vacuolar protein breakdown|up-regulation of vacuolar protein degradation|activation of vacuolar protein catabolism|positive regulation of vacuolar protein catabolic process|up-regulation of vacuolar protein catabolic process|upregulation of vacuolar protein breakdown|up regulation of vacuolar protein catabolism|positive regulation of vacuolar protein degradation|positive regulation of vacuolar protein catabolism|upregulation of protein catabolic process in the vacuole|upregulation of vacuolar protein catabolism|up regulation of vacuolar protein degradation|positive regulation of vacuolar protein breakdown|upregulation of vacuolar protein degradation|up regulation of vacuolar protein breakdown|up regulation of vacuolar protein catabolic process|activation of vacuolar protein catabolic process|up-regulation of vacuolar protein breakdown|activation of protein catabolic process in the vacuole							rl	2015-06-12T09:10:49Z					biological_process											owl:Class	
GO:0102598	biolink:NamedThing	3alpha-hydroxy-ent-sandaracopimardiene 7-beta-monooxygenase activity	Catalysis of the reaction: ent-sandaracopimaradien-3-beta-ol + NADPH + H+ + O2 <=> oryzalexin D + NADP + H2O.	tmpzr1t_l9r_go_relaxed.owl					RHEA:41472|MetaCyc:RXN-15382|EC:1.14.14.123									molecular_function											owl:Class	
GO:1902628	biolink:NamedThing	positive regulation of assembly of large subunit precursor of preribosome	Any process that activates or increases the frequency, rate or extent of assembly of a large subunit precursor of preribosome.	tmpzr1t_l9r_go_relaxed.owl	up regulation of 66S preribosome formation|positive regulation of 66S preribosome formation|up regulation of assembly of large subunit precursor of preribosome|up-regulation of 66S preribosome formation|up-regulation of assembly of large subunit precursor of preribosome|up-regulation of 66S preribosome assembly|up regulation of preribosome, large subunit precursor formation|upregulation of preribosome, large subunit precursor formation|upregulation of assembly of large subunit precursor of preribosome|up regulation of 66S preribosome assembly|positive regulation of preribosome, large subunit precursor formation|activation of 66S preribosome assembly|positive regulation of 66S preribosome assembly|activation of 66S preribosome formation|activation of preribosome, large subunit precursor formation|activation of assembly of large subunit precursor of preribosome|upregulation of 66S preribosome formation|upregulation of 66S preribosome assembly|up-regulation of preribosome, large subunit precursor formation							tb	2014-01-16T22:11:55Z					biological_process											owl:Class	
GO:0005358	biolink:NamedThing	high-affinity glucose:proton symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucose + H+ = glucose + H+. This activity is constitutive and therefore always present, regardless of demand. Symporter activity enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported together in the same direction in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.	tmpzr1t_l9r_go_relaxed.owl	high-affinity hydrogen/glucose transporter activity|high-affinity hydrogen:glucose symporter activity|high-affinity hydrogen:glucose transporter activity													molecular_function											owl:Class	
GO:2000967	biolink:NamedThing	negative regulation of cell wall polysaccharide catabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of cell wall polysaccharide catabolic process.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of cell wall polysaccharide breakdown							tt	2011-08-01T02:30:33Z					biological_process											owl:Class	
GO:0015750	biolink:NamedThing	pentose transmembrane transport	The process in which pentose is transported across a lipid bilayer, from one side of a membrane to the other. A pentose is any aldose with a chain of five carbon atoms in the molecule.	tmpzr1t_l9r_go_relaxed.owl	pentose transport													biological_process											owl:Class	
GO:1904786	biolink:NamedThing	negative regulation of asymmetric protein localization involved in cell fate determination	Any process that stops, prevents or reduces the frequency, rate or extent of asymmetric protein localization involved in cell fate determination.	tmpzr1t_l9r_go_relaxed.owl	downregulation of asymmetric protein localization involved in cell fate commitment|negative regulation of asymmetric protein localization resulting in cell fate commitment|down-regulation of asymmetric protein localization resulting in cell fate commitment|downregulation of asymmetric protein localization involved in cell fate determination|negative regulation of cell fate commitment, asymmetric protein localization|downregulation of cell fate commitment, asymmetric protein localization|down regulation of asymmetric protein localization resulting in cell fate commitment|down regulation of cell fate commitment, asymmetric protein localization|inhibition of cell fate commitment, asymmetric protein localization|down regulation of asymmetric protein localization involved in cell fate determination|down regulation of asymmetric protein localization involved in cell fate commitment|negative regulation of asymmetric protein localization involved in cell fate commitment|downregulation of asymmetric protein localization resulting in cell fate commitment|inhibition of asymmetric protein localization involved in cell fate determination|down-regulation of asymmetric protein localization involved in cell fate commitment|inhibition of asymmetric protein localization involved in cell fate commitment|downregulation of asymmetric protein localisation involved in cell fate determination|down-regulation of asymmetric protein localisation involved in cell fate determination|negative regulation of asymmetric protein localisation involved in cell fate determination|down-regulation of asymmetric protein localization involved in cell fate determination|down regulation of asymmetric protein localisation involved in cell fate determination|inhibition of asymmetric protein localisation involved in cell fate determination|down-regulation of cell fate commitment, asymmetric protein localization|inhibition of asymmetric protein localization resulting in cell fate commitment					wrm-1 in C. Elegans (Q10953) in PMID:17476329 (IMP)		es	2015-11-03T12:11:13Z					biological_process											owl:Class	
GO:0034359	biolink:NamedThing	mature chylomicron	A chylomicron that contains apolipoprotein C2 (APOC2), a cofactor for lipoprotein lipase (LPL) activity, and has a mean diameter of 500 nm and density of 0.95g/ml. Mature chylomicron particles transport exogenous (dietary) lipids from the intestines to other body tissues, via the blood and lymph.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0005762	biolink:NamedThing	mitochondrial large ribosomal subunit	The larger of the two subunits of a mitochondrial ribosome. Two sites on the ribosomal large subunit are involved in translation: the aminoacyl site (A site) and peptidyl site (P site).	tmpzr1t_l9r_go_relaxed.owl	39S ribosomal subunit, mitochondrial													cellular_component											owl:Class	
GO:0039023	biolink:NamedThing	pronephric duct morphogenesis	The process in which the anatomical structures of the pronephric duct are generated and organized. The pronephric duct collects the filtrate from the pronephric tubules and opens to the exterior of the kidney.	tmpzr1t_l9r_go_relaxed.owl								bf	2010-07-02T10:18:09Z					biological_process											owl:Class	
GO:0045881	biolink:NamedThing	positive regulation of sporulation resulting in formation of a cellular spore	Any process that activates or increases the frequency, rate or extent of sporulation.	tmpzr1t_l9r_go_relaxed.owl	upregulation of sporulation|stimulation of sporulation|up regulation of sporulation|up-regulation of sporulation|activation of sporulation													biological_process											owl:Class	
GO:0097210	biolink:NamedThing	response to gonadotropin-releasing hormone	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gonadotropin-releasing hormone stimulus. Gonadotropin-releasing hormone (GnRH) is a peptide hormone responsible for the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) from the anterior pituitary. GnRH is synthesized and released by the hypothalamus.	tmpzr1t_l9r_go_relaxed.owl	response to GnRH							pr	2012-01-09T08:48:56Z					biological_process											owl:Class	
GO:0001139	biolink:NamedThing	RNA polymerase II complex recruiting activity	Binding to an RNA polymerase II (Pol II) complex, typically composed of twelve subunits, and with another protein, macromolecule, or complex, permitting those molecules to function in a coordinated way in order to facilitate the aggregation, arrangement and bonding together of proteins on an RNA polymerase II promoter DNA to form the transcriptional preinitiation complex (PIC), the formation of which is a prerequisite for transcription by RNA polymerase.	tmpzr1t_l9r_go_relaxed.owl	core RNA polymerase II recruiting transcription factor activity|transcription factor activity, core RNA polymerase II recruiting							krc	2011-01-20T05:55:01Z					molecular_function											owl:Class	
GO:0102382	biolink:NamedThing	rebaudioside B glucosyltransferase activity	Catalysis of the reaction: rebaudioside B + UDP-alpha-D-glucose <=> rebaudioside A + UDP + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-13518									molecular_function											owl:Class	
GO:1990054	biolink:NamedThing	response to temozolomide	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a temozolomide stimulus.	tmpzr1t_l9r_go_relaxed.owl						Note that this term is in the subset of terms that should not be used for direct manual annotation of gene products. It was created to be used for cross-referencing by other ontologies. Direct annotations to this term may be amended during annotation QC.		pr	2013-02-22T10:09:44Z					biological_process											owl:Class	
GO:0070578	biolink:NamedThing	RISC-loading complex	A trimeric protein complex required for the formation of a mature RNA-induced silencing complex (RISC). In humans the complex is composed of the endonuclease Dicer (DICER1), TRBP (TARBP2) and the Argonaute protein Ago2 (EIF2C2/AGO2). Within the complex, Dicer and TRBP are required to process precursor miRNAs (pre-miRNAs) to mature miRNAs and then load them onto Ago2. Ago2 bound to the mature miRNA constitutes the minimal RISC and may subsequently dissociate from Dicer and TRBP. This complex has endoribonuclease activity.	tmpzr1t_l9r_go_relaxed.owl	microRNA loading complex|RLC|miRLC							mah	2009-04-22T01:40:19Z					cellular_component											owl:Class	
GO:0046436	biolink:NamedThing	D-alanine metabolic process	The chemical reactions and pathways involving D-alanine, the D-enantiomer of the amino acid alanine, i.e. (2R)-2-aminopropanoic acid.	tmpzr1t_l9r_go_relaxed.owl	D-alanine metabolism													biological_process											owl:Class	
GO:1905404	biolink:NamedThing	positive regulation of activated CD8-positive, alpha-beta T cell apoptotic process	Any process that activates or increases the frequency, rate or extent of activated CD8-positive, alpha-beta T cell apoptotic process.	tmpzr1t_l9r_go_relaxed.owl	up regulation of activated CD8-positive, alpha-beta T lymphocyte apoptosis|positive regulation of activated CD8-positive, alpha-beta T-cell apoptotic process|up-regulation of activated CD8-positive, alpha-beta T-lymphocyte apoptotic process|up regulation of activated CD8-positive, alpha-beta T-cell apoptosis|up-regulation of activated CD8-positive, alpha-beta T cell apoptosis|upregulation of activated CD8-positive, alpha-beta T lymphocyte apoptotic process|activation of activated CD8-positive, alpha-beta T-cell apoptotic process|up regulation of activated CD8-positive, alpha-beta T cell apoptotic process|upregulation of activated CD8-positive, alpha-beta T cell apoptotic process|activation of activated CD8-positive, alpha-beta T-cell apoptosis|up-regulation of activated CD8-positive, alpha-beta T-cell apoptosis|upregulation of activated CD8-positive, alpha-beta T lymphocyte apoptosis|upregulation of activated CD8-positive, alpha-beta T cell apoptosis|up-regulation of activated CD8-positive, alpha-beta T lymphocyte apoptosis|positive regulation of activated CD8-positive, alpha-beta T cell apoptosis|upregulation of activated CD8-positive, alpha-beta T-cell apoptotic process|activation of activated CD8-positive, alpha-beta T-lymphocyte apoptotic process|activation of activated CD8-positive, alpha-beta T lymphocyte apoptosis|activation of activated CD8-positive, alpha-beta T cell apoptotic process|upregulation of activated CD8-positive, alpha-beta T-lymphocyte apoptotic process|upregulation of activated CD8-positive, alpha-beta T-lymphocyte apoptosis|up regulation of activated CD8-positive, alpha-beta T-cell apoptotic process|activation of activated CD8-positive, alpha-beta T-lymphocyte apoptosis|up-regulation of activated CD8-positive, alpha-beta T lymphocyte apoptotic process|upregulation of activated CD8-positive, alpha-beta T-cell apoptosis|positive regulation of activated CD8-positive, alpha-beta T-lymphocyte apoptotic process|activation of activated CD8-positive, alpha-beta T cell apoptosis|up-regulation of activated CD8-positive, alpha-beta T cell apoptotic process|positive regulation of activated CD8-positive, alpha-beta T lymphocyte apoptotic process|positive regulation of activated CD8-positive, alpha-beta T-lymphocyte apoptosis|up regulation of activated CD8-positive, alpha-beta T lymphocyte apoptotic process|positive regulation of activated CD8-positive, alpha-beta T-cell apoptosis|up regulation of activated CD8-positive, alpha-beta T-lymphocyte apoptotic process|up regulation of activated CD8-positive, alpha-beta T cell apoptosis|up regulation of activated CD8-positive, alpha-beta T-lymphocyte apoptosis|up-regulation of activated CD8-positive, alpha-beta T-lymphocyte apoptosis|activation of activated CD8-positive, alpha-beta T lymphocyte apoptotic process|up-regulation of activated CD8-positive, alpha-beta T-cell apoptotic process|positive regulation of activated CD8-positive, alpha-beta T lymphocyte apoptosis							pga	2016-08-25T09:14:10Z					biological_process											owl:Class	
GO:0051747	biolink:NamedThing	cytosine C-5 DNA demethylase activity	Catalysis of the reaction: methyl-dCpdG DNA + H2O = dCpdG DNA + methanol. This reaction is the hydrolytic removal of the methyl group on the 5 position of cytosine in DNA.	tmpzr1t_l9r_go_relaxed.owl	DNA methyltransferase activity acting on cytosine C-5|hydrolytic DNA demethylase activity|DNA demethylase activity													molecular_function											owl:Class	
GO:0102690	biolink:NamedThing	isopentenyladenine UDP glycosyltransferase activity	Catalysis of the reaction: UDP-alpha-D-glucose + N(6)-dimethylallyladenine = H+ + 9-(alpha-D-glucosyl)-N(6)-isopentenyladenine + UDP.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-4728									molecular_function											owl:Class	
GO:0106055	biolink:NamedThing	mannosyl-oligosaccharide 1,2-alpha-mannosidase complex	A protein complex capable of catalysing the hydrolysis of the terminal (1->2)-linked alpha-D-mannose residues in an oligo-mannose oligosaccharide.	tmpzr1t_l9r_go_relaxed.owl						An example is MNL1 (P38888) in Saccharomyces cerevisiae. PMID:19124653 (by physical interaction evidence).		hjd	2017-09-14T15:23:28Z					cellular_component											owl:Class	
GO:0090599	biolink:NamedThing	alpha-glucosidase activity	Catalysis of the hydrolysis of terminal, non-reducing alpha-linked alpha-D-glucose residue with release of alpha-D-glucose.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-9036727|EC:3.2.1.20|Reactome:R-HSA-9036729			tb	2014-08-22T14:33:31Z					molecular_function											owl:Class	
GO:0019544	biolink:NamedThing	arginine catabolic process to glutamate	The chemical reactions and pathways resulting in the breakdown of arginine into other compounds, including glutamate.	tmpzr1t_l9r_go_relaxed.owl	arginine degradation to glutamate|arginine breakdown to glutamate				MetaCyc:ARGASEDEG-PWY|MetaCyc:ARG-GLU-PWY									biological_process											owl:Class	
GO:0070769	biolink:NamedThing	alphaIIb-beta3 integrin-CIB complex	A protein complex that consists of an alphaIIb-beta3 integrin complex bound to CIB, a protein that binds calcium as well as the alphaIIb-beta3 integrin.	tmpzr1t_l9r_go_relaxed.owl	ITGA2B-ITGB3-CIB1 complex							mah	2009-06-29T05:20:01Z					cellular_component											owl:Class	
GO:0017126	biolink:NamedThing	nucleologenesis	A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a nucleolus, a small, dense body one or more of which are present in the nucleus of eukaryotic cells.	tmpzr1t_l9r_go_relaxed.owl	nucleolus biogenesis|nucleolus assembly													biological_process											owl:Class	
GO:0034552	biolink:NamedThing	respiratory chain complex II assembly	The aggregation, arrangement and bonding together of a set of components to form respiratory chain complex II.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0061975	biolink:NamedThing	articular cartilage development	The process whose specific outcome is the progression of articular cartilage over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl	articular cartilage of joint development							dph	2018-02-12T19:57:31Z					biological_process											owl:Class	
GO:0010697	biolink:NamedThing	negative regulation of mitotic spindle pole body separation	Any process that decreases the rate, frequency or extent of the process involving the release of duplicated mitotic spindle pole bodies (SPBs) and their migration away from each other within the nuclear membrane.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of SPB separation													biological_process											owl:Class	
GO:0010695	biolink:NamedThing	regulation of mitotic spindle pole body separation	Any process that modulates the rate, frequency or extent of the process involving the release of duplicated mitotic spindle pole bodies (SPBs) and their migration away from each other within the nuclear membrane.	tmpzr1t_l9r_go_relaxed.owl	regulation of SPB separation													biological_process											owl:Class	
GO:0034706	biolink:NamedThing	sodium channel complex	An ion channel complex through which sodium ions pass.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0034272	biolink:NamedThing	phosphatidylinositol 3-kinase complex, class III, type II	A class III phosphatidylinositol 3-kinase complex that is involved in vacuolar protein sorting (VPS) via endosomes. In budding yeast, this complex consists of Vps30p, Vps34p, Vps38 and Vps15p.	tmpzr1t_l9r_go_relaxed.owl	phosphatidylinositol 3-kinase complex II|PtdIns-3-kinase complex II					Note that this term should not be confused with '1-phosphatidylinositol-4-phosphate 3-kinase, class IA complex; GO:0005943' or '1-phosphatidylinositol-4-phosphate 3-kinase, class IB complex ; GO:0005944'.								cellular_component											owl:Class	
GO:0009768	biolink:NamedThing	photosynthesis, light harvesting in photosystem I	After a photon of light is absorbed by one of the many chlorophyll molecules, in one of the light-harvesting complexes of an antenna on photosystem I, some of the absorbed energy is transferred to the pair of chlorophyll molecules in the reaction center.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0052543	biolink:NamedThing	callose deposition in cell wall	Any process in which callose is transported to, and/or maintained in, the cell wall. Callose is a linear 1,3-beta-d-glucan formed from UDP-glucose and is found in certain plant cell walls.	tmpzr1t_l9r_go_relaxed.owl	callose localization in cell wall|cell wall callose deposition|cell wall callose localization													biological_process											owl:Class	
GO:0007141	biolink:NamedThing	male meiosis I	A cell cycle process comprising the steps by which a cell progresses through male meiosis I, the first meiotic division in the male germline.	tmpzr1t_l9r_go_relaxed.owl	male meiosis I nuclear division													biological_process											owl:Class	
GO:0002876	biolink:NamedThing	positive regulation of chronic inflammatory response to antigenic stimulus	Any process that activates or increases the frequency, rate, or extent of a chronic inflammatory response to an antigenic stimulus.	tmpzr1t_l9r_go_relaxed.owl	stimulation of chronic inflammatory response to antigenic stimulus|upregulation of chronic inflammatory response to antigenic stimulus|up regulation of chronic inflammatory response to antigenic stimulus|up-regulation of chronic inflammatory response to antigenic stimulus|activation of chronic inflammatory response to antigenic stimulus													biological_process											owl:Class	
GO:1903652	biolink:NamedThing	modulation by virus of host cytoplasmic transport	Modulation by an infecting virus of host cytoplasmic transport.	tmpzr1t_l9r_go_relaxed.owl	regulation by virus of host cytoplasmic transport|regulation by virus of host cytoplasmic streaming|viral modulation of host cytoplasmic trafficking							jl	2014-11-24T17:22:04Z					biological_process											owl:Class	
GO:1990608	biolink:NamedThing	mitotic spindle pole body localization	A process in which a mitotic spindle pole body is transported to, or maintained in, a specific cellular location.	tmpzr1t_l9r_go_relaxed.owl	spindle pole body localisation in nuclear envelope|spindle pole body localization in nuclear envelope|spindle pole body localization to nuclear envelope|mitotic spindle pole body localization to nuclear envelope|spindle pole body positioning|spindle pole body docking|establishment of spindle pole body localisation|establishment of spindle pole body localization|establishment and maintenance of spindle pole body localization	https://github.com/geneontology/go-ontology/issues/19149						vw	2009-05-06T02:35:32Z			GO:0071789|GO:0070632		biological_process											owl:Class	
GO:0046482	biolink:NamedThing	para-aminobenzoic acid metabolic process	The chemical reactions and pathways involving para-aminobenzoic acid, an intermediate in the synthesis of folic acid, a compound which some organisms, e.g. prokaryotes, eukaryotic microbes, and plants, can synthesize de novo. Others, notably mammals, cannot. In yeast, it is present as a factor in the B complex of vitamins.	tmpzr1t_l9r_go_relaxed.owl	p-aminobenzoic acid metabolic process|PABA metabolism|vitamin Bx metabolic process|p-aminobenzoic acid metabolism|vitamin Bx metabolism|4-aminobenzoic acid metabolism|para-aminobenzoic acid metabolism|4-aminobenzoic acid metabolic process|PABA metabolic process													biological_process											owl:Class	
GO:0019742	biolink:NamedThing	pentacyclic triterpenoid metabolic process	The chemical reactions and pathways involving pentacyclic triterpenoid compounds, terpenoids with six isoprene units and 5 carbon rings.	tmpzr1t_l9r_go_relaxed.owl	pentacyclic triterpenoid metabolism													biological_process											owl:Class	
GO:0045302	biolink:NamedThing	choloylglycine hydrolase activity	Catalysis of the reaction: 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholan-24-oylglycine + H2O = 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholanate + glycine.	tmpzr1t_l9r_go_relaxed.owl	choloyltaurine hydrolase activity|bile salt hydrolase activity|glycocholase activity|3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-oylglycine amidohydrolase activity				MetaCyc:CHOLOYLGLYCINE-HYDROLASE-RXN|RHEA:19353|EC:3.5.1.24									molecular_function											owl:Class	
GO:2000180	biolink:NamedThing	negative regulation of androgen biosynthetic process	Any process that stops, prevents, or reduces the frequency, rate or extent of androgen biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of androgen synthesis|negative regulation of androgen formation|negative regulation of androgen anabolism|negative regulation of androgen biosynthesis							dph	2010-10-13T12:43:17Z					biological_process											owl:Class	
GO:1904865	biolink:NamedThing	positive regulation of beta-catenin-TCF complex assembly	Any process that activates or increases the frequency, rate or extent of beta-catenin-TCF complex assembly.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of beta-catenin/T-cell factor complex formation|upregulation of beta-catenin/T-cell factor complex formation|activation of beta-catenin/T-cell factor complex assembly|positive regulation of beta-catenin/LEF complex assembly|up-regulation of beta-catenin/T-cell factor complex formation|up regulation of beta-catenin/T-cell factor complex assembly|up-regulation of beta-catenin-TCF complex formation|up-regulation of beta-catenin/lymphoid enhancer binding factor complex assembly|upregulation of beta-catenin/lymphoid enhancer binding factor complex assembly|positive regulation of beta-catenin/lymphoid enhancer binding factor complex assembly|positive regulation of beta-catenin/lymphoid enhancer binding factor complex formation|activation of beta-catenin-TCF complex assembly|upregulation of beta-catenin/LEF complex formation|up regulation of beta-catenin/lymphoid enhancer binding factor complex formation|up regulation of beta-catenin-TCF complex formation|up regulation of beta-catenin-TCF complex assembly|activation of beta-catenin-TCF complex formation|positive regulation of beta-catenin/T-cell factor complex assembly|activation of beta-catenin/T-cell factor complex formation|up regulation of beta-catenin/LEF complex assembly|positive regulation of beta-catenin/LEF complex formation|up regulation of beta-catenin/lymphoid enhancer binding factor complex assembly|upregulation of beta-catenin-TCF complex formation|up regulation of beta-catenin/T-cell factor complex formation|upregulation of beta-catenin/T-cell factor complex assembly|up-regulation of beta-catenin/LEF complex formation|up-regulation of beta-catenin/lymphoid enhancer binding factor complex formation|activation of beta-catenin/lymphoid enhancer binding factor complex assembly|upregulation of beta-catenin-TCF complex assembly|activation of beta-catenin/lymphoid enhancer binding factor complex formation|up-regulation of beta-catenin-TCF complex assembly|activation of beta-catenin/LEF complex formation|up-regulation of beta-catenin/LEF complex assembly|positive regulation of beta-catenin-TCF complex formation|upregulation of beta-catenin/LEF complex assembly|up-regulation of beta-catenin/T-cell factor complex assembly|upregulation of beta-catenin/lymphoid enhancer binding factor complex formation|up regulation of beta-catenin/LEF complex formation|activation of beta-catenin/LEF complex assembly							bf	2015-12-17T13:50:53Z					biological_process											owl:Class	
GO:0047578	biolink:NamedThing	4-hydroxyglutamate transaminase activity	Catalysis of the reaction: 4-hydroxy-L-glutamate + 2-oxoglutarate = 4-hydroxy-2-oxoglutarate + L-glutamate.	tmpzr1t_l9r_go_relaxed.owl	4-hydroxy-L-glutamate:2-oxoglutarate aminotransferase activity|4-hydroxyglutamate aminotransferase activity				Reactome:R-HSA-6784393|MetaCyc:4-HYDROXYGLUTAMATE-AMINOTRANSFERASE-RXN|RHEA:10480|EC:2.6.1.23									molecular_function											owl:Class	
GO:0032941	biolink:NamedThing	secretion by tissue	The controlled release of a substance by a tissue.	tmpzr1t_l9r_go_relaxed.owl	tissue secretion|expulsion of gland contents													biological_process											owl:Class	
GO:0031001	biolink:NamedThing	response to brefeldin A	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a brefeldin A stimulus.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0031691	biolink:NamedThing	alpha-1A adrenergic receptor binding	Binding to an alpha-1A adrenergic receptor.	tmpzr1t_l9r_go_relaxed.owl	alpha-1A adrenergic receptor ligand													molecular_function											owl:Class	
GO:0051368	biolink:NamedThing	peptidyl-threonine octanoylation	The octanoylation of peptidyl-threonine to form peptidyl-O3-octanoyl-L-threonine, typical of the protein ghrelin.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0386									biological_process											owl:Class	
GO:1901675	biolink:NamedThing	negative regulation of histone H3-K27 acetylation	Any process that stops, prevents or reduces the frequency, rate or extent of histone H3-K27 acetylation.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of histone H3K27 acetylation|inhibition of histone H3K27 acetylation|down-regulation of histone H3-K27 acetylation|downregulation of histone H3-K27 acetylation|negative regulation of histone H3K27 acetylation|negative regulation of histone H3 acetylation at K27|inhibition of histone H3-K27 acetylation|inhibition of histone H3 acetylation at K27|downregulation of histone H3K27 acetylation|downregulation of histone H3 acetylation at K27|down regulation of histone H3K27 acetylation|down regulation of histone H3-K27 acetylation|down regulation of histone H3 acetylation at K27|down-regulation of histone H3 acetylation at K27							vk	2012-11-22T12:06:40Z					biological_process											owl:Class	
GO:0102845	biolink:NamedThing	1-18:3-2-16:0-monogalactosyldiacylglycerol desaturase activity	Catalysis of the reaction: 1-18:3-2-16:0-monogalactosyldiacylglycerol + O2 + a reduced electron acceptor <=> 1-18:3-2-16:1-monogalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-8307									molecular_function											owl:Class	
GO:0005901	biolink:NamedThing	caveola	A membrane raft that forms small pit, depression, or invagination that communicates with the outside of a cell and extends inward, indenting the cytoplasm and the cell membrane. Examples include flask-shaped invaginations of the plasma membrane in adipocytes associated with caveolin proteins, and minute pits or incuppings of the cell membrane formed during pinocytosis.  Caveolae may be pinched off to form free vesicles within the cytoplasm.	tmpzr1t_l9r_go_relaxed.owl	caveolar membrane|caveolae				Wikipedia:Caveolae							GO:0016599		cellular_component											owl:Class	
GO:1904770	biolink:NamedThing	intramembranous bone morphogenesis	The developmental process by which an intramembranous bone is generated and organized.	tmpzr1t_l9r_go_relaxed.owl	intramembranous bones morphogenesis|membrane bone morphogenesis							dos	2015-10-28T11:46:04Z					biological_process											owl:Class	
GO:0070152	biolink:NamedThing	mitochondrial isoleucyl-tRNA aminoacylation	The process of coupling isoleucine to isoleucyl-tRNA in a mitochondrion, catalyzed by isoleucyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0006428	biolink:NamedThing	isoleucyl-tRNA aminoacylation	The process of coupling isoleucine to isoleucyl-tRNA, catalyzed by isoleucyl-tRNA synthetase. The isoleucyl-tRNA synthetase is a  class-I synthetase. The activated amino acid is transferred to the 2'-OH group of a isoleucine-accetping tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0019695	biolink:NamedThing	choline metabolic process	The chemical reactions and pathways involving choline (2-hydroxyethyltrimethylammonium), an amino alcohol that occurs widely in living organisms as a constituent of certain types of phospholipids and in the neurotransmitter acetylcholine.	tmpzr1t_l9r_go_relaxed.owl	choline metabolism													biological_process											owl:Class	
GO:0033241	biolink:NamedThing	regulation of cellular amine catabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of amines.	tmpzr1t_l9r_go_relaxed.owl	regulation of amine breakdown|regulation of amine catabolism|regulation of amine degradation													biological_process											owl:Class	
GO:1900623	biolink:NamedThing	regulation of monocyte aggregation	Any process that modulates the frequency, rate or extent of monocyte aggregation.	tmpzr1t_l9r_go_relaxed.owl	regulation of mononuclear phagocyte aggregation							vk	2012-05-21T01:07:17Z					biological_process											owl:Class	
GO:0020036	biolink:NamedThing	Maurer's cleft	A disk-like structure that appears at the periphery of a red blood cell infected by an apicomplexan parasite, characterized by a translucent lumen and an electron-dense coat of variable thickness; often appears to be tethered to the host cell membrane by fibrous connections with the erythrocyte cytoskeleton.	tmpzr1t_l9r_go_relaxed.owl	Maurers cleft													cellular_component											owl:Class	
GO:0035446	biolink:NamedThing	cysteine-glucosaminylinositol ligase activity	Catalysis of the reaction: 1-(2-amino-2-deoxy-alpha-D-glucopyranoside)-1D-myo-inositol + L-cysteine + ATP = 1-D-myo-inosityl-2-L-cysteinylamido-2-deoxy-alpha-D-glucopyranoside + AMP + diphosphate + 2 H+. 1-(2-amino-2-deoxy-alpha-D-glucopyranoside)-1D-myo-inositol is also known as glucosaminyl-inositol or GlcN-Ins, and 1-D-myo-inosityl-2-L-cysteinylamido-2-deoxy-alpha-D-glucopyranoside as desacetylmycothiol or Cys-GlcN-Ins.	tmpzr1t_l9r_go_relaxed.owl	MshC ligase|L-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligase|desacetylmycothiol synthase				RHEA:26176|MetaCyc:RXN1G-4|EC:6.3.1.13			bf	2010-04-14T11:33:06Z					molecular_function											owl:Class	
GO:0032759	biolink:NamedThing	positive regulation of TRAIL production	Any process that activates or increases the frequency, rate, or extent of TRAIL production.	tmpzr1t_l9r_go_relaxed.owl	stimulation of TRAIL production|positive regulation of TRAIL biosynthetic process|upregulation of TRAIL production|activation of TRAIL production|up-regulation of TRAIL production|up regulation of TRAIL production											GO:0045556		biological_process											owl:Class	
GO:0098731	biolink:NamedThing	skeletal muscle satellite stem cell maintenance involved in skeletal muscle regeneration	Any process by which the number of skeletal muscle satellite stem cells in a skeletal muscle is maintained during skeletal muscle regeneration. There are at least two mechanisms by which this is achieved. Skeletal muscle satellite stem cell asymmetric division ensures satellite stem cell numbers are kept constant. Symmetric division of these cells amplifies the number of skeletal muscle satellite stem cells.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0014834	biolink:NamedThing	skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration	Any process by which the number of skeletal muscle satellite cells in a skeletal muscle is maintained during muscle regeneration. There are at least three mechanisms by which this is achieved. Skeletal muscle satellite stem cell asymmetric division ensures satellite stem cell numbers are kept constant. Symmetric division of these cells amplifies the number of skeletal muscle satellite stem cells.  Some adult skeletal muscle myoblasts (descendants of activated satellite cells) can develop back into quiescent satellite cells, replenishing the overall pool of satellite cells.	tmpzr1t_l9r_go_relaxed.owl	satellite cell compartment self-renewal involved in skeletal muscle regeneration|satellite cell population maintenance|satellite cell self-renewal													biological_process											owl:Class	
GO:0002877	biolink:NamedThing	regulation of acute inflammatory response to non-antigenic stimulus	Any process that modulates the frequency, rate, or extent of an acute inflammatory response to a non-antigenic stimulus.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0003919	biolink:NamedThing	FMN adenylyltransferase activity	Catalysis of the reaction: ATP + FMN = diphosphate + FAD.	tmpzr1t_l9r_go_relaxed.owl	riboflavin adenine dinucleotide pyrophosphorylase activity|adenosine triphosphate-riboflavin mononucleotide transadenylase activity|flavin adenine dinucleotide synthetase activity|riboflavine adenine dinucleotide adenylyltransferase activity|riboflavin mononucleotide adenylyltransferase activity|FAD diphosphorylase activity|FAD pyrophosphorylase activity|FAD synthetase activity|ATP:FMN adenylyltransferase activity|adenosine triphosphate-riboflavine mononucleotide transadenylase activity				RHEA:17237|MetaCyc:FADSYN-RXN|KEGG_REACTION:R00161|EC:2.7.7.2|Reactome:R-HSA-196929									molecular_function											owl:Class	
GO:1900010	biolink:NamedThing	regulation of corticotropin-releasing hormone receptor activity	Any process that modulates the frequency, rate or extent of corticotropin-releasing hormone receptor activity.	tmpzr1t_l9r_go_relaxed.owl	regulation of CRF receptor activity|regulation of CRH receptor activity|regulation of adrenocorticotropin-releasing hormone receptor activity|regulation of corticotropin-releasing factor receptor activity							pr	2012-01-10T02:27:23Z					biological_process											owl:Class	
GO:0098901	biolink:NamedThing	regulation of cardiac muscle cell action potential	Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a cardiac muscle cell. This typically occurs via modulation of the activity or expression of voltage-gated ion channels.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0140544	biolink:NamedThing	septin collar organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising the septin collar.	tmpzr1t_l9r_go_relaxed.owl	cellular bud neck septin hourglass organization	https://github.com/geneontology/go-ontology/issues/19534						pg	2020-11-10T13:47:48Z					biological_process											owl:Class	
GO:0032185	biolink:NamedThing	septin cytoskeleton organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising septin complexes and their associated proteins.	tmpzr1t_l9r_go_relaxed.owl	septin cytoskeleton organisation|septin cytoskeleton organization and biogenesis													biological_process											owl:Class	
GO:0009230	biolink:NamedThing	thiamine catabolic process	The chemical reactions and pathways resulting in the breakdown of thiamine (vitamin B1), a water soluble vitamin present in fresh vegetables and meats, especially liver.	tmpzr1t_l9r_go_relaxed.owl	thiamine catabolism|vitamin B1 catabolism|vitamin B1 catabolic process|thiamine breakdown|thiamine degradation|thiamin catabolic process													biological_process											owl:Class	
GO:0062163	biolink:NamedThing	pseudohyphal septin ring assembly	The aggregation, arrangement and bonding together of septins and associated proteins to form a tight ring-shaped structure that forms in the division plane at the junction between the mother cell and a pseudohyphal projection.	tmpzr1t_l9r_go_relaxed.owl								dph	2019-11-07T15:46:26Z					biological_process											owl:Class	
GO:1900698	biolink:NamedThing	regulation of o-orsellinic acid biosynthetic process	Any process that modulates the frequency, rate or extent of o-orsellinic acid biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of o-orsellinic acid formation|regulation of o-orsellinic acid biosynthesis|regulation of o-orsellinic acid synthesis|regulation of o-orsellinic acid anabolism							di	2012-05-22T04:56:46Z					biological_process											owl:Class	
GO:0090178	biolink:NamedThing	regulation of establishment of planar polarity involved in neural tube closure	Any process that modulates the rate, frequency, or extent of the establishment of planar polarity involved in neural tube closure, the coordinated organization of groups of cells in the plane of an epithelium that contributes to the closure of the neural tube.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-12-14T11:14:27Z					biological_process											owl:Class	
GO:0000820	biolink:NamedThing	regulation of glutamine family amino acid metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving amino acids of the glutamine family, comprising arginine, glutamate, glutamine and proline.	tmpzr1t_l9r_go_relaxed.owl	regulation of glutamine family amino acid metabolism													biological_process											owl:Class	
GO:0008779	biolink:NamedThing	acyl-[acyl-carrier-protein]-phospholipid O-acyltransferase activity	Catalysis of the reaction: acyl-[acyl-carrier protein] + O-(2-acyl-sn-glycero-3-phospho)ethanolamine = [acyl-carrier protein] + O-(1-beta-acyl-2-acyl-sn-glycero-3-phospho)ethanolamine.	tmpzr1t_l9r_go_relaxed.owl	acyl-ACP-phospholipid O-acyltransferase activity|acyl-acyl-carrier-protein:O-(2-acyl-sn-glycero-3-phospho)-ethanolamine O-acyltransferase activity|acyl-acyl-carrier-protein-phospholipid O-acyltransferase activity|acyl-[acyl-carrier protein]-phospholipid O-acyltransferase activity				MetaCyc:ACYLGPEACYLTRANS-RXN|RHEA:10304|EC:2.3.1.40									molecular_function											owl:Class	
GO:0004363	biolink:NamedThing	glutathione synthase activity	Catalysis of the reaction: L-gamma-glutamyl-L-cysteine + ATP + glycine = ADP + glutathione + 2 H(+) + phosphate.	tmpzr1t_l9r_go_relaxed.owl	gamma-L-glutamyl-L-cysteine:glycine ligase (ADP-forming)|glutathione synthetase activity|GSH synthetase activity				Reactome:R-HSA-5602901|RHEA:13557|MetaCyc:GLUTATHIONE-SYN-RXN|Reactome:R-HSA-174394|KEGG_REACTION:R00497|EC:6.3.2.3									molecular_function											owl:Class	
GO:0019354	biolink:NamedThing	siroheme biosynthetic process	The chemical reactions and pathways resulting in the formation of siroheme, a tetrahydroporphyrin with adjacent, reduced pyrrole rings.	tmpzr1t_l9r_go_relaxed.owl	siroheme synthesis|siroheme anabolism|siroheme synthase activity|sirohaem biosynthesis|siroheme formation|sirohaem biosynthetic process|siroheme biosynthesis				MetaCyc:PWY-5194									biological_process											owl:Class	
GO:0044179	biolink:NamedThing	hemolysis in other organism	The cytolytic destruction of red blood cells, with the release of intracellular hemoglobin, in one organism by another.	tmpzr1t_l9r_go_relaxed.owl	hemolysis of cells in other organism|hemolysis of erythrocytes in other organism|hemolysis of RBCs in other organism|hemolysis of red blood cells in other organism							jl	2009-09-04T03:36:00Z					biological_process											owl:Class	
GO:0047101	biolink:NamedThing	2-oxoisovalerate dehydrogenase (acylating) activity	Catalysis of the reaction: NAD+ + CoA + 2-keto-isovalerate = NADH + CO2 + isobutyryl-CoA.	tmpzr1t_l9r_go_relaxed.owl	2-oxoisovalerate dehydrogenase activity|3-methyl-2-oxobutanoate:NAD+ 2-oxidoreductase (CoA-methyl-propanoylating)				EC:1.2.1.25|MetaCyc:1.2.1.25-RXN|RHEA:13997									molecular_function											owl:Class	
GO:0031961	biolink:NamedThing	cortisol receptor binding	Binding to a cortisol receptor.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0035259	biolink:NamedThing	glucocorticoid receptor binding	Binding to a glucocorticoid receptor.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0102225	biolink:NamedThing	4,4'-diaponeurosporene desaturase activity	Catalysis of the reaction: 4,4'-diaponeurosporene + FAD + H+ <=> 4,4'-diapolycopene + FADH2.	tmpzr1t_l9r_go_relaxed.owl					RHEA:31407|MetaCyc:RXN-12258									molecular_function											owl:Class	
GO:1990197	biolink:NamedThing	methionine-importing ABC transporter complex	An ATP-binding cassette (ABC) transporter complex that is capable of methionine-importing activity. An example is the bacterial MetNIQ methionine transporter, that consists of the dimeric ATPase subunit MetN located at the cytoplasmic side of the plasma membrane and the dimeric transmembrane subunit MetI. MetQ is regarded as the periplasmic methionine-binding chaperon subunit, and is capable of transporting methionine from the periplasm into the cytoplasm in an ATP-dependent manner.	tmpzr1t_l9r_go_relaxed.owl	MetNIQ transport complex|ATP-dependent methionine importer complex|ATP-binding cassette (ABC) methionine importer complex|MetNIQ transporter|MetNIQ complex|ATP-dependent methionine importing complex|methionine transporter complex, ATP-dependent|MetNIQ transporter complex|MetNI transport complex|ATP-dependent methionine-importing complex|methionine transporter|MetNI complex|methionine transporter complex|methionine transport complex|MetNI transporter complex|MetNI transporter	https://github.com/geneontology/go-ontology/issues/21619						bhm	2013-09-26T09:38:26Z					cellular_component											owl:Class	
GO:1904386	biolink:NamedThing	response to L-phenylalanine derivative	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-phenylalanine derivative stimulus.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-06-23T17:56:19Z					biological_process											owl:Class	
GO:0033916	biolink:NamedThing	beta-agarase activity	Catalysis of the hydrolysis of (1->4)-beta-D-galactosidic linkages in agarose, giving the tetramer as the predominant product.	tmpzr1t_l9r_go_relaxed.owl	agarose 3-glycanohydrolase activity|agarose 4-glycanohydrolase activity|AgaB|agarase activity|AgaA				EC:3.2.1.81									molecular_function											owl:Class	
GO:0036015	biolink:NamedThing	response to interleukin-3	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-3 stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to IL-3							bf	2011-10-12T10:08:26Z					biological_process											owl:Class	
GO:0045158	biolink:NamedThing	electron transporter, transferring electrons within cytochrome b6/f complex of photosystem II activity	Enables the directed movement of electrons within the cytochrome b6/f complex of photosystem II.	tmpzr1t_l9r_go_relaxed.owl	cytochrome|cytochrome b6|cytochrome b/b6|cytochrome f													molecular_function											owl:Class	
GO:0008050	biolink:NamedThing	female courtship behavior	The behavior of a female, for the purpose of attracting a sexual partner.	tmpzr1t_l9r_go_relaxed.owl	female courtship behaviour													biological_process											owl:Class	
GO:0044584	biolink:NamedThing	cellodextrin binding	Binding to a cellodextrin, a glucose polymer of 2 or more glucose monomers.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-04-24T04:52:05Z					molecular_function											owl:Class	
GO:0061482	biolink:NamedThing	response to irinotecan	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an irinotecan stimulus.	tmpzr1t_l9r_go_relaxed.owl								dph	2012-11-07T09:15:03Z					biological_process											owl:Class	
GO:0015707	biolink:NamedThing	nitrite transport	The directed movement of nitrite into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0004949	biolink:NamedThing	cannabinoid receptor activity	Combining with a cannabinoid to initiate a change in cell activity. Cannabinoids are a class of diverse chemical compounds that include the endocannabinoids and the phytocannabinoids.	tmpzr1t_l9r_go_relaxed.owl	endocannabinoid receptor activity|cannaboid receptor													molecular_function											owl:Class	
GO:0033565	biolink:NamedThing	ESCRT-0 complex	A protein complex required for the recycling of Golgi proteins, formation of lumenal membranes and sorting of ubiquitinated proteins into those membranes. This complex includes Vps1p and Hse1p in yeast and the Hrs and STAM proteins in mammals.	tmpzr1t_l9r_go_relaxed.owl	Vps27p-Hse1p complex|Hrs/STAM complex													cellular_component											owl:Class	
GO:0035522	biolink:NamedThing	monoubiquitinated histone H2A deubiquitination	The removal of the ubiquitin group from a monoubiquitinated histone H2A protein.	tmpzr1t_l9r_go_relaxed.owl	monoubiquitinated histone H2A deubiquitinylation|monoubiquitinated histone H2A deubiquitylation							bf	2010-05-04T04:32:53Z					biological_process											owl:Class	
GO:0035521	biolink:NamedThing	monoubiquitinated histone deubiquitination	The removal of the ubiquitin group from a monoubiquitinated histone protein.	tmpzr1t_l9r_go_relaxed.owl	monoubiquitinated histone deubiquitylation|monoubiquitinated histone deubiquitinylation							bf	2010-05-04T04:32:04Z					biological_process											owl:Class	
GO:0070083	biolink:NamedThing	clathrin-sculpted monoamine transport vesicle membrane	The lipid bilayer surrounding a clathrin-sculpted monoamine transport vesicle.	tmpzr1t_l9r_go_relaxed.owl	clathrin sculpted monoamine transport vesicle membrane|clathrin sculpted monoamine constitutive secretory pathway transport vesicle membrane													cellular_component											owl:Class	
GO:0120046	biolink:NamedThing	regulation of protein localization to medial cortical node	Any process that modulates the frequency, rate or extent of protein localization to a medial cortical node.	tmpzr1t_l9r_go_relaxed.owl								krc	2017-06-02T17:29:23Z					biological_process											owl:Class	
GO:0019428	biolink:NamedThing	allantoin biosynthetic process	The chemical reactions and pathways resulting in the formation of allantoin, (2,5-dioxo-4-imidazolidinyl)urea.	tmpzr1t_l9r_go_relaxed.owl	allantoin synthesis|allantoin biosynthesis|allantoin formation|allantoin anabolism				MetaCyc:URSIN-PWY									biological_process											owl:Class	
GO:0061809	biolink:NamedThing	NAD+ nucleotidase, cyclic ADP-ribose generating	Catalysis of the reaction: NAD+ + H2O = nicotinamide + ADP-ribose that proceeds in a stepwise fashion by ADP-ribosyl cyclase activity followed by cyclic ADP-ribose hydrolase activity.	tmpzr1t_l9r_go_relaxed.owl					EC:3.2.2.6|MetaCyc:NADNUCLEOSID-RXN			dph	2016-11-11T13:14:13Z					molecular_function											owl:Class	
GO:0016432	biolink:NamedThing	tRNA-uridine aminocarboxypropyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + tRNA uridine = 5'-methylthioadenosine + tRNA 3-(3-amino-3-carboxypropyl)-uridine.	tmpzr1t_l9r_go_relaxed.owl	S-adenosyl-L-methionine:tRNA-uridine 3-(3-amino-3-carboxypropyl)transferase activity				RHEA:12300|EC:2.5.1.25|MetaCyc:2.5.1.25-RXN									molecular_function											owl:Class	
GO:0044643	biolink:NamedThing	envenomation resulting in positive regulation of complement activation, alternative pathway in other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant positive regulation of complement activation via the alternative pathway in the bitten/stung organism.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-07-11T11:56:48Z					biological_process											owl:Class	
GO:0044642	biolink:NamedThing	envenomation resulting in modulation of complement activation, alternative pathway in other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant modulation of complement activation via the alternative pathway in the bitten/stung organism.	tmpzr1t_l9r_go_relaxed.owl	envenomation resulting in regulation of complement activation, alternative pathway in other organism							jl	2012-07-11T11:53:12Z					biological_process											owl:Class	
GO:0032780	biolink:NamedThing	negative regulation of ATP-dependent activity	Any process that stops or reduces the rate of an ATP-dependent activity.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of ATPase activity|down regulation of ATPase activity|down-regulation of ATPase activity|negative regulation of adenosinetriphosphatase activity|inhibition of ATPase activity|downregulation of ATPase activity	https://github.com/geneontology/go-ontology/issues/22371												biological_process											owl:Class	
GO:0047332	biolink:NamedThing	diphosphate-serine phosphotransferase activity	Catalysis of the reaction: L-serine + diphosphate = O-phospho-L-serine + H(+) + phosphate.	tmpzr1t_l9r_go_relaxed.owl	diphosphate:L-serine O-phosphotransferase activity|pyrophosphate--serine phosphotransferase activity|pyrophosphate-L-serine phosphotransferase activity				KEGG_REACTION:R00584|MetaCyc:2.7.1.80-RXN|RHEA:23764|EC:2.7.1.80									molecular_function											owl:Class	
GO:0051537	biolink:NamedThing	2 iron, 2 sulfur cluster binding	Binding to a 2 iron, 2 sulfur (2Fe-2S) cluster; this cluster consists of two iron atoms, with two inorganic sulfur atoms found between the irons and acting as bridging ligands.	tmpzr1t_l9r_go_relaxed.owl	iron-sulphur cluster 2Fe-2S binding|iron-sulfur cluster 2Fe-2S binding|diiron disulfide cluster binding|2Fe-2S cluster binding|diiron disulphide cluster binding|2 iron, 2 sulphur cluster binding|2 Fe 2 S cluster binding													molecular_function											owl:Class	
GO:0070656	biolink:NamedThing	mechanoreceptor differentiation involved in mechanosensory epithelium regeneration	Differentiation of new mechanoreceptors to replace those lost or destroyed by injury.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-05-28T04:08:13Z					biological_process											owl:Class	
GO:0071424	biolink:NamedThing	rRNA (cytosine-N4-)-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing N4-methylcytosine.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-12-15T03:46:52Z					molecular_function											owl:Class	
GO:0061313	biolink:NamedThing	fibroblast growth factor receptor signaling pathway involved in heart development	The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands and contributing to the progression of the heart over time.	tmpzr1t_l9r_go_relaxed.owl	fibroblast growth factor receptor signalling pathway involved in heart development							dph	2010-09-24T08:15:08Z					biological_process											owl:Class	
GO:0001900	biolink:NamedThing	positive regulation of cytolysis by symbiont of host cells	Any process in which an organism activates or increases the frequency, rate or extent of cytolysis by that organism of cells in its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	up-regulation by symbiont of cytolysis of host cells|upregulation by symbiont of cytolysis of host cells|up regulation by symbiont of cytolysis of host cells|stimulation by symbiont of cytolysis of host cells|positive regulation by symbiont of cytolysis of host cells|activation by symbiont of cytolysis of host cells													biological_process											owl:Class	
GO:1901412	biolink:NamedThing	positive regulation of tetrapyrrole biosynthetic process from glutamate	Any process that activates or increases the frequency, rate or extent of tetrapyrrole biosynthetic process from glutamate.	tmpzr1t_l9r_go_relaxed.owl	activation of tetrapyrrole biosynthetic process from glutamate|upregulation of tetrapyrrole formation from glutamate|activation of tetrapyrrole anabolism from glutamate|positive regulation of tetrapyrrole biosynthesis from glutamate|upregulation of tetrapyrrole anabolism from glutamate|positive regulation of tetrapyrrole synthesis from glutamate|up regulation of tetrapyrrole synthesis from glutamate|up-regulation of tetrapyrrole synthesis from glutamate|upregulation of tetrapyrrole biosynthetic process from glutamate|up-regulation of tetrapyrrole anabolism from glutamate|up-regulation of tetrapyrrole formation from glutamate|upregulation of tetrapyrrole synthesis from glutamate|up regulation of tetrapyrrole formation from glutamate|up-regulation of tetrapyrrole biosynthetic process from glutamate|upregulation of tetrapyrrole biosynthesis from glutamate|up regulation of tetrapyrrole anabolism from glutamate|positive regulation of tetrapyrrole formation from glutamate|positive regulation of tetrapyrrole anabolism from glutamate|up-regulation of tetrapyrrole biosynthesis from glutamate|up regulation of tetrapyrrole biosynthesis from glutamate|activation of tetrapyrrole biosynthesis from glutamate|up regulation of tetrapyrrole biosynthetic process from glutamate|activation of tetrapyrrole synthesis from glutamate|activation of tetrapyrrole formation from glutamate							tt	2012-10-01T16:22:21Z					biological_process											owl:Class	
GO:1903703	biolink:NamedThing	enterocyte differentiation	The process in which a relatively unspecialized cell acquires the specialized features of an enterocyte.	tmpzr1t_l9r_go_relaxed.owl								cls	2014-12-03T15:08:51Z					biological_process											owl:Class	
GO:0009697	biolink:NamedThing	salicylic acid biosynthetic process	The chemical reactions and pathways resulting in the formation of salicylic acid (2-hydroxybenzoic acid), a derivative of benzoic acid.	tmpzr1t_l9r_go_relaxed.owl	salicylate biosynthetic process|salicylic acid biosynthesis|salicylic acid formation|salicylic acid anabolism|salicylic acid synthesis				MetaCyc:PWY-981									biological_process											owl:Class	
GO:0046537	biolink:NamedThing	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity	Catalysis of the reaction: 2-phospho-D-glycerate = 3-phospho-D glycerate; this reaction does not require the cofactor 2,3-bisphosphoglycerate.	tmpzr1t_l9r_go_relaxed.owl	PGAM-i													molecular_function											owl:Class	
GO:0017044	biolink:NamedThing	melanocyte-stimulating hormone activity	The action characteristic of melanocyte-stimulating hormone, any of three peptide hormones that are produced by the intermediate lobe of the pituitary gland and, upon receptor binding, cause dispersal of melanosomes in melanophores of poikilothermic vertebrates.	tmpzr1t_l9r_go_relaxed.owl	alpha-melanocyte stimulating hormone activity|melanocyte stimulating hormone activity|alpha-melanophore stimulating hormone activity													molecular_function											owl:Class	
GO:0005179	biolink:NamedThing	hormone activity	The action characteristic of a hormone, any substance formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells in the same organism, upon which it has a specific regulatory action. The term was originally applied to agents with a stimulatory physiological action in vertebrate animals (as opposed to a chalone, which has a depressant action). Usage is now extended to regulatory compounds in lower animals and plants, and to synthetic substances having comparable effects; all bind receptors and trigger some biological process.	tmpzr1t_l9r_go_relaxed.owl	peptide hormone|lipopeptide hormone|glycopeptide hormone|cAMP generating peptide activity					Also consider annotating to 'receptor agonist activity ; GO:0048018'.								molecular_function											owl:Class	
GO:1904431	biolink:NamedThing	positive regulation of t-circle formation	Any process that activates or increases the frequency, rate or extent of t-circle formation.	tmpzr1t_l9r_go_relaxed.owl	upregulation of telomeric circle formation|up regulation of t-circle formation|positive regulation of telomeric circle formation|activation of t-circle formation|upregulation of t-circle formation|up-regulation of telomeric circle formation|activation of telomeric circle formation|up regulation of telomeric circle formation|up-regulation of t-circle formation							nc	2015-07-03T15:15:58Z					biological_process											owl:Class	
GO:0010480	biolink:NamedThing	microsporocyte differentiation	The process aimed at the progression of a microsporocyte cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. A microsporocyte is a diploid (2n) cell that undergoes meiosis and forms four haploid (1n) microspores; also called microspore mother cell and, in seed plants, pollen mother cell.	tmpzr1t_l9r_go_relaxed.owl	pollen mother cell differentiation													biological_process											owl:Class	
GO:2000613	biolink:NamedThing	negative regulation of thyroid-stimulating hormone secretion	Any process that stops, prevents or reduces the frequency, rate or extent of thyroid-stimulating hormone secretion.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of thyroid stimulating hormone secretion|negative regulation of TSH secretion							yaf	2011-04-18T12:56:20Z					biological_process											owl:Class	
GO:0036222	biolink:NamedThing	XTP diphosphatase activity	Catalysis of the reaction: XTP + H2O <=> H+ + XDP + monophosphate.	tmpzr1t_l9r_go_relaxed.owl	hypoxanthine/xanthine dNTP pyrophosphatase|XTPase activity|XTP/dITP diphosphatase|XTP pyrophosphohydrolase activity	https://github.com/geneontology/go-ontology/issues/19078			EC:3.6.1.66|Reactome:R-HSA-2509831|KEGG_REACTION:R02720|MetaCyc:RXN0-5074|RHEA:28610|MetaCyc:RXN0-1603	While XTP is not produced by cells, deamination of purine bases can result in accumulation of such nucleotides as ITP, dITP, XTP, and dXTP. XTPase contributes to the removal of these abnormal bases from the cellular pool of nucleotide triphosphates.		bf	2012-05-08T01:47:59Z			GO:0103024		molecular_function											owl:Class	
GO:1990080	biolink:NamedThing	2-phenylethylamine receptor activity	Combining with the biogenic amine 2-phenylethylamine to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	beta-phenylethylamine receptor activity							sp	2013-04-30T10:53:19Z					molecular_function											owl:Class	
GO:0007361	biolink:NamedThing	establishment of posterior gap gene boundaries	Specification of the borders of posterior gap gene expression mediated largely by the effects of other gap genes; in insects this is exemplified by hunchback and tailless repression of knirps.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0007356	biolink:NamedThing	thorax and anterior abdomen determination	Specification of the central (trunk) regions of the embryo by the gap genes; exemplified in insects by the actions of the Kruppel gene product.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0048733	biolink:NamedThing	sebaceous gland development	The process whose specific outcome is the progression of the sebaceous gland over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0010939	biolink:NamedThing	regulation of necrotic cell death	Any process that modulates the rate, frequency or extent of necrotic cell death. Necrotic cell death is a cell death process that is morphologically characterized by a gain in cell volume (oncosis), swelling of organelles, plasma membrane rupture and subsequent loss of intracellular contents.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0071349	biolink:NamedThing	cellular response to interleukin-12	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-12 stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to IL-12							mah	2009-12-11T02:49:40Z					biological_process											owl:Class	
GO:0031838	biolink:NamedThing	haptoglobin-hemoglobin complex	A protein complex formed by the stable binding of a haptoglobin to hemoglobin.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:2000379	biolink:NamedThing	positive regulation of reactive oxygen species metabolic process	Any process that activates or increases the frequency, rate or extent of reactive oxygen species metabolic process.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of ROS metabolic process|positive regulation of reactive oxygen species metabolism							mah	2011-02-11T02:06:57Z					biological_process											owl:Class	
GO:0034988	biolink:NamedThing	Fc-gamma receptor I complex binding	Binding to one or more specific sites on the Fc-gamma receptor I complex. The complex functions primarily as an activating receptor for IgG.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0043425	biolink:NamedThing	bHLH transcription factor binding	Binding to a basic Helix-Loop-Helix (bHLH) superfamily of transcription factors, important regulatory components in transcriptional networks of many developmental pathways.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0140297	biolink:NamedThing	DNA-binding transcription factor binding	Binding to a DNA-binding transcription factor, a protein that interacts with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription.	tmpzr1t_l9r_go_relaxed.owl	activating transcription factor binding|transcription activator binding|repressing transcription factor binding	https://github.com/geneontology/go-ontology/issues/19354						pg	2018-11-28T12:48:20Z			GO:0070491|GO:0033613|GO:0001107		molecular_function											owl:Class	
GO:0120180	biolink:NamedThing	cell-substrate junction disassembly	The disaggregation of a cell-substrate junction into its constituent components.	tmpzr1t_l9r_go_relaxed.owl								krc	2018-07-12T17:33:35Z					biological_process											owl:Class	
GO:0150115	biolink:NamedThing	cell-substrate junction organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cell-substrate junction. A cell-substrate junction is a specialized region of connection between a cell and the extracellular matrix.	tmpzr1t_l9r_go_relaxed.owl								bc	2019-11-14T11:06:29Z					biological_process											owl:Class	
GO:1900023	biolink:NamedThing	positive regulation of D-erythro-sphingosine kinase activity	Any process that activates or increases the frequency, rate or extent of D-erythro-sphingosine kinase activity.	tmpzr1t_l9r_go_relaxed.owl	up regulation of sphingosine kinase activity|positive regulation of sphingosine kinase activity|up regulation of D-erythro-sphingosine kinase activity							bf	2012-01-11T04:30:33Z					biological_process											owl:Class	
GO:1900022	biolink:NamedThing	regulation of D-erythro-sphingosine kinase activity	Any process that modulates the frequency, rate or extent of D-erythro-sphingosine kinase activity.	tmpzr1t_l9r_go_relaxed.owl	regulation of sphingosine kinase activity							bf	2012-01-11T04:30:29Z					biological_process											owl:Class	
GO:0015611	biolink:NamedThing	ABC-type D-ribose transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + D-ribose(out) -> ADP + phosphate + D-ribose(in).	tmpzr1t_l9r_go_relaxed.owl	D-ribose-importing ATPase activity|D-ribose porter activity				MetaCyc:ABC-28-RXN|RHEA:29903|EC:7.5.2.8									molecular_function											owl:Class	
GO:0046000	biolink:NamedThing	positive regulation of ecdysteroid secretion	Any process that activates or increases the frequency, rate or extent of the regulated release of ecdysteroid.	tmpzr1t_l9r_go_relaxed.owl	activation of ecdysteroid secretion|stimulation of ecdysteroid secretion|upregulation of ecdysteroid secretion|up regulation of ecdysteroid secretion|up-regulation of ecdysteroid secretion													biological_process											owl:Class	
GO:0071513	biolink:NamedThing	phosphopantothenoylcysteine decarboxylase complex	A protein complex that catalyzes decarboxylation of 4'-phosphopantothenoylcysteine to yield 4'-phosphopantetheine; this is the third step in the biosynthesis of Coenzyme A. The complex is homotrimeric in many eukaryotes, but is a heterotrimer in Saccharomyces.	tmpzr1t_l9r_go_relaxed.owl						See also the molecular function term 'acetolactate synthase activity ; GO:0003984'.		mah	2010-01-05T05:23:13Z					cellular_component											owl:Class	
GO:0016577	biolink:NamedThing	histone demethylation	The modification of histones by removal of methyl groups.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0006482	biolink:NamedThing	protein demethylation	The removal of a methyl group, from a protein amino acid. A methyl group is derived from methane by the removal of a hydrogen atom.	tmpzr1t_l9r_go_relaxed.owl	protein amino acid demethylation													biological_process											owl:Class	
GO:1990799	biolink:NamedThing	mitochondrial tRNA wobble position uridine thiolation	The process in which a uridine residue at position 34 in the anticodon of a mitochondrial tRNA is post-transcriptionally thiolated at the C2 position. This process involves transfer of a sulfur from cysteine to position C2 by several steps.	tmpzr1t_l9r_go_relaxed.owl								vw	2015-07-13T08:15:15Z					biological_process											owl:Class	
GO:0070899	biolink:NamedThing	mitochondrial tRNA wobble uridine modification	The process in which a uridine in position 34 of a mitochondrial tRNA is post-transcriptionally modified.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-09-02T03:14:13Z					biological_process											owl:Class	
GO:0071505	biolink:NamedThing	response to mycophenolic acid	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mycophenolic acid stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to mycophenolate							mah	2009-12-18T03:46:00Z					biological_process											owl:Class	
GO:0019529	biolink:NamedThing	taurine catabolic process	The chemical reactions and pathways resulting in the breakdown of taurine (2-aminoethanesulfonic acid), a sulphur-containing amino acid derivative important in the metabolism of fats.	tmpzr1t_l9r_go_relaxed.owl	taurine breakdown|taurine catabolism|taurine degradation				MetaCyc:TAURINEDEG-PWY									biological_process											owl:Class	
GO:0032961	biolink:NamedThing	negative regulation of inositol trisphosphate biosynthetic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of inositol trisphosphate.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of myo-inositol trisphosphate biosynthesis|negative regulation of myo-inositol trisphosphate biosynthetic process|negative regulation of IP3 biosynthetic process|negative regulation of inositol trisphosphate biosynthesis|negative regulation of IP3 biosynthesis|negative regulation of inositol trisphosphate formation|negative regulation of inositol trisphosphate anabolism|negative regulation of inositol trisphosphate synthesis													biological_process											owl:Class	
GO:0042350	biolink:NamedThing	GDP-L-fucose biosynthetic process	The chemical reactions and pathways resulting in the formation of GDP-L-fucose, a substance composed of L-fucose in glycosidic linkage with guanosine diphosphate.	tmpzr1t_l9r_go_relaxed.owl	GDP-L-fucose formation|GDP-L-fucose biosynthesis|GDP-L-fucose anabolism|GDP-L-fucose synthesis													biological_process											owl:Class	
GO:0006663	biolink:NamedThing	platelet activating factor biosynthetic process	The chemical reactions and pathways resulting in the formation of platelet activating factor, 1-O-alkyl-2-acetyl-sn-glycerol 3-phosphocholine, where alkyl = hexadecyl or octadecyl. Platelet activating factor is an inflammatory mediator released from a variety of cells in response to various stimuli.	tmpzr1t_l9r_go_relaxed.owl	PAF biosynthesis|PAF biosynthetic process|platelet activating factor synthesis|platelet activating factor biosynthesis|platelet activating factor formation|platelet activating factor anabolism													biological_process											owl:Class	
GO:0008611	biolink:NamedThing	ether lipid biosynthetic process	The chemical reactions and pathways resulting in the formation of ether lipids, lipids that contain (normally) one lipid alcohol in ether linkage to one of the carbon atoms (normally C-1) of glycerol.	tmpzr1t_l9r_go_relaxed.owl	ether lipid biosynthesis|ether lipid formation|ether lipid anabolism|ether lipid synthesis|plasmalogen biosynthetic process													biological_process											owl:Class	
GO:0051677	biolink:NamedThing	pullulan biosynthetic process	The chemical reactions and pathways resulting in the formation of pullulan, a neutral linear polysaccharide composed of repeating units of maltotriose joined by alpha-(1,6)-linkages.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0051141	biolink:NamedThing	negative regulation of NK T cell proliferation	Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer T cell proliferation.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of natural killer T cell proliferation|downregulation of NK T cell proliferation|down regulation of NK T cell proliferation|negative regulation of NKT cell proliferation|inhibition of NK T cell proliferation|negative regulation of NK T-lymphocyte proliferation|negative regulation of NK T-cell proliferation|negative regulation of natural T cell proliferation|down-regulation of NK T cell proliferation|negative regulation of NK T lymphocyte proliferation|negative regulation of NT cell proliferation													biological_process											owl:Class	
GO:0090735	biolink:NamedThing	DNA repair complex assembly	The aggregation, arrangement and bonding together of a set of components to form a DNA repair complex.	tmpzr1t_l9r_go_relaxed.owl								tb	2017-02-06T16:42:27Z					biological_process											owl:Class	
GO:0042056	biolink:NamedThing	chemoattractant activity	Providing the environmental signal that initiates the directed movement of a motile cell or organism towards a higher concentration of that signal.	tmpzr1t_l9r_go_relaxed.owl	attractant													molecular_function											owl:Class	
GO:1901326	biolink:NamedThing	response to tetracycline	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tetracycline stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2012-08-30T10:13:26Z					biological_process											owl:Class	
GO:0000050	biolink:NamedThing	urea cycle	The sequence of reactions by which arginine is synthesized from ornithine, then cleaved to yield urea and regenerate ornithine. The overall reaction equation is NH3 + CO2 + aspartate + 3 ATP + 2 H2O = urea + fumarate + 2 ADP + 2 phosphate + AMP + diphosphate.	tmpzr1t_l9r_go_relaxed.owl	ornithine cycle|urea biosynthetic process|urea biosynthesis				Wikipedia:Urea_cycle							GO:0006871|GO:0006594		biological_process											owl:Class	
GO:0051324	biolink:NamedThing	prophase	The cell cycle phase which is the first stage of M phase of meiosis and mitosis and during which chromosomes condense and the two daughter centrioles and their asters migrate toward the poles of the cell.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Prophase	Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).								biological_process											owl:Class	
GO:1903491	biolink:NamedThing	response to simvastatin	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a simvastatin stimulus. Simvastatin is a statin used as a cholesterol-lowering and anti-cardiovascular disease drug.	tmpzr1t_l9r_go_relaxed.owl						Note that this term is in the subset of terms that should not be used for direct manual annotation of gene products. It was created to be used for cross-referencing by other ontologies. Direct annotations to this term may be amended during annotation QC.		hp	2014-09-25T10:58:06Z					biological_process											owl:Class	
GO:0036273	biolink:NamedThing	response to statin	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a statin stimulus. Statins are organooxygen compounds whose structure is related to compactin (mevastatin) and which may be used as an anticholesteremic drug due its EC:1.1.1.34/EC:1.1.1.88 (hydroxymethylglutaryl-CoA reductase) inhibitory properties.	tmpzr1t_l9r_go_relaxed.owl	response to hydroxymethylglutaryl-CoA reductase inhibitor|response to HMG-CoA reductase inhibitor					Note that this term is in the subset of terms that should not be used for direct manual annotation of gene products. It was created to be used for cross-referencing by other ontologies. Direct annotations to this term may be amended during annotation QC.		bf	2012-07-09T01:54:01Z					biological_process											owl:Class	
GO:0031137	biolink:NamedThing	regulation of conjugation with cellular fusion	Any process that modulates the rate or frequency of conjugation with cellular fusion.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1990356	biolink:NamedThing	sumoylated E2 ligase complex	A protein complex consisting of a SUMO (small ubiquitin-related modifier) protein bound to a SUMO-conjugating E2 ligase. Sumoylation of the E2 ligase is an intermediate step required for the formation of covalent bonds between a SUMO protein and its ultimate protein target. SUMO is transferred to the E2 ligase by a SUMO-activating E1 enzyme. Sumoylation of the target protein is either facilitated directly by the sumoylated E2 ligase or aided by an optional E3 ligase.	tmpzr1t_l9r_go_relaxed.owl						An example of this is UBC9 in human (UniProt symbol P63279) in PMID:18691969 (inferred from direct assay).		bhm	2014-04-02T14:06:56Z					cellular_component											owl:Class	
GO:0102212	biolink:NamedThing	unsaturated chondroitin disaccharide hydrolase activity	Catalysis of the reaction: beta-D-4-deoxy-Delta(4)-GlcpA-(1->3)-beta-D-GalpNAc6S + H2O = 5-dehydro-4-deoxy-D-glucuronate + N-acetyl-beta-D-galactosamine 6-sulfate.	tmpzr1t_l9r_go_relaxed.owl					EC:3.2.1.180|MetaCyc:RXN-12177|RHEA:31647									molecular_function											owl:Class	
GO:0031264	biolink:NamedThing	death-inducing signaling complex	A protein complex formed by the association of signaling proteins with a death receptor upon ligand binding. The complex includes procaspases and death domain-containing proteins in addition to the ligand-bound receptor, and may control the activation of caspases 8 and 10.	tmpzr1t_l9r_go_relaxed.owl	death receptor-induced signalling complex|DISC|death-inducing signalling complex|DISC protein complex|death receptor-induced signaling complex				Wikipedia:Death-inducing_signaling_complex	Gene products that may be annotated to this term include: 1) ligand-bound receptors such as FAS/CD95 (though care should be taken because FAS can also act as a non-apoptotic signal transducer); 2) signaling molecules such as FADD (FAS-associated protein with a death domain), cIAPs (cellular inhibitor of apoptosis proteins), c-FLIPs and caspases 8 and 10.								cellular_component											owl:Class	
GO:0044548	biolink:NamedThing	S100 protein binding	Binding to a S100 protein. S100 is a small calcium and zinc binding protein produced in astrocytes that is implicated in Alzheimer's disease, Down Syndrome and ALS.	tmpzr1t_l9r_go_relaxed.owl	S100 beta binding|S100 alpha binding|S100 binding							jl	2012-03-22T03:23:51Z			GO:0048155|GO:0048154		molecular_function											owl:Class	
GO:0060705	biolink:NamedThing	neuron differentiation involved in salivary gland development	The process in which a relatively unspecialized cell acquires specialized structural and/or functional features that characterize the neurons of the salivary gland.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-06-09T09:35:52Z					biological_process											owl:Class	
GO:0043984	biolink:NamedThing	histone H4-K16 acetylation	The modification of histone H4 by the addition of an acetyl group to a lysine residue at position 16 of the histone.	tmpzr1t_l9r_go_relaxed.owl	histone H4 acetylation at K16													biological_process											owl:Class	
GO:0055060	biolink:NamedThing	asymmetric neuroblast division resulting in ganglion mother cell formation	Any process resulting in the physical partitioning and separation of a neuroblast into a neuroblast and a ganglion mother cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0055059	biolink:NamedThing	asymmetric neuroblast division	The process resulting in the physical partitioning and separation of a neuroblast into two daughter cells with different developmental potentials.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0071101	biolink:NamedThing	alpha4-beta1 integrin-JAM2 complex	A protein complex that consists of an alpha4-beta1 integrin complex bound to the cell adhesion molecule JAM2.	tmpzr1t_l9r_go_relaxed.owl	ITGA4-ITGB1-JAM2 complex							mah	2009-11-06T04:52:59Z					cellular_component											owl:Class	
GO:1902340	biolink:NamedThing	negative regulation of chromosome condensation	Any process that stops, prevents or reduces the frequency, rate or extent of chromosome condensation.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of nuclear chromosome condensation|downregulation of chromosome condensation|inhibition of eukaryotic chromosome condensation|down-regulation of eukaryotic chromosome condensation|down-regulation of nuclear chromosome condensation|inhibition of chromosome condensation|downregulation of nuclear chromosome condensation|down regulation of chromosome condensation|downregulation of eukaryotic chromosome condensation|down regulation of eukaryotic chromosome condensation|negative regulation of eukaryotic chromosome condensation|down-regulation of chromosome condensation|inhibition of nuclear chromosome condensation|down regulation of nuclear chromosome condensation							dgf	2013-07-29T20:54:14Z					biological_process											owl:Class	
GO:0032448	biolink:NamedThing	DNA hairpin binding	Binding to a DNA region containing a hairpin. A hairpin structure forms when a DNA strand folds back on itself and intrachain base pairing occurs between inverted repeat sequences.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1901872	biolink:NamedThing	ecgonone methyl ester biosynthetic process	The chemical reactions and pathways resulting in the formation of ecgonone methyl ester.	tmpzr1t_l9r_go_relaxed.owl	ecgonone methyl ester formation|ecgonone methyl ester biosynthesis|ecgonone methyl ester synthesis|ecgonone methyl ester anabolism							ms	2013-02-04T11:58:39Z					biological_process											owl:Class	
GO:0036385	biolink:NamedThing	nucleoid DNA packaging	Any process in which DNA and associated proteins are formed into a compact, orderly structure within a nucleoid.	tmpzr1t_l9r_go_relaxed.owl								bf	2013-05-30T10:36:05Z					biological_process											owl:Class	
GO:0002141	biolink:NamedThing	stereocilia ankle link	A stereocilia coupling link that is composed of a fine filament present in developing stereocilia that couples the bases of individual stereocilia to one another. They are not present in mature stereocilia.	tmpzr1t_l9r_go_relaxed.owl								hjd	2009-05-06T10:31:56Z					cellular_component											owl:Class	
GO:0004858	biolink:NamedThing	dUTP pyrophosphatase inhibitor activity	Binds to and stops, prevents or reduces the activity of dUTP pyrophosphatase.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0097352	biolink:NamedThing	autophagosome maturation	Removal of PI3P and Atg8/LC3 after the closure of the phagophore and before the fusion with the endosome/lysosome (e.g. mammals and insects) or vacuole (yeast), and that very likely destabilizes other Atg proteins and thus enables their efficient dissociation and recycling.	tmpzr1t_l9r_go_relaxed.owl	autophagic vacuole fusion|autophagic vacuole maturation|autophagosome fusion							pr	2012-06-28T03:12:18Z			GO:0000046		biological_process											owl:Class	
GO:1905778	biolink:NamedThing	negative regulation of exonuclease activity	Any process that stops, prevents or reduces the frequency, rate or extent of exonuclease activity.	tmpzr1t_l9r_go_relaxed.owl	down regulation of exonuclease IX activity|downregulation of exonuclease activity|inhibition of exonuclease IX activity|down regulation of exonuclease activity|inhibition of exonuclease activity|down-regulation of exonuclease IX activity|down-regulation of exonuclease activity|downregulation of exonuclease IX activity|negative regulation of exonuclease IX activity							nc	2016-12-21T21:32:16Z					biological_process											owl:Class	
GO:0033967	biolink:NamedThing	box C/D RNA metabolic process	The chemical reactions and pathways involving box C/D type small nucleolar RNA.	tmpzr1t_l9r_go_relaxed.owl	box C/D sRNA metabolic process|box C/D snoRNA metabolic process	https://github.com/geneontology/go-ontology/issues/20416												biological_process											owl:Class	
GO:0031092	biolink:NamedThing	platelet alpha granule membrane	The lipid bilayer surrounding the platelet alpha granule.	tmpzr1t_l9r_go_relaxed.owl	platelet alpha-granule membrane													cellular_component											owl:Class	
GO:0032771	biolink:NamedThing	regulation of tyrosinase activity	Any process that modulates the activity of a tyrosinase enzyme.	tmpzr1t_l9r_go_relaxed.owl	regulation of monophenol monooxygenase activity|regulation of monophenol oxygenase activity	https://github.com/geneontology/go-ontology/issues/21024												biological_process											owl:Class	
GO:0060301	biolink:NamedThing	positive regulation of cytokine activity	Any process that increases the rate, frequency or extent of the activity of a molecule that controls the survival, growth, differentiation and effector function of tissues and cells.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0032028	biolink:NamedThing	myosin head/neck binding	Binding to the head/neck region of a myosin heavy chain.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0007634	biolink:NamedThing	optokinetic behavior	The behavior of an organism pertaining to movement of the eyes and of objects in the visual field, as in nystagmus.	tmpzr1t_l9r_go_relaxed.owl	optokinetic behaviour													biological_process											owl:Class	
GO:0007632	biolink:NamedThing	visual behavior	The behavior of an organism in response to a visual stimulus.	tmpzr1t_l9r_go_relaxed.owl	visual behaviour|behavioural response to visual stimulus|behavioral response to visual stimulus													biological_process											owl:Class	
GO:0102739	biolink:NamedThing	(gibberellin-36), 2-oxoglutarate:oxygen oxidoreductase activity	Catalysis of the reaction: gibberellin A36 + O2 + 2-oxoglutarate <=> H+ + gibberellin A4 + succinate + 2 carbon dioxide.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-7591									molecular_function											owl:Class	
GO:0099038	biolink:NamedThing	ceramide floppase activity	Catalysis of the movement of ceramide from the cytosolic to the exoplasmic leaftlet of a membrane, using energy from the hydrolysis of ATP.	tmpzr1t_l9r_go_relaxed.owl	ceramide floppase activity (cytosolic to exoplasmic leaftlet)|ATP-dependent ceramide transporter activity|ceramide-translocating ATPase activity|ATPase-coupled ceramide transporter activity													molecular_function											owl:Class	
GO:0003296	biolink:NamedThing	apoptotic process involved in atrial ventricular junction remodeling	Any apoptotic process that contributes to the reorganization of tissue resulting in the maturation of the atrial ventricular junction.	tmpzr1t_l9r_go_relaxed.owl	apoptosis involved in atrial ventricular junction remodeling|apoptosis involved in atrio-ventricular junction remodeling|apoptosis involved in atrioventricular junction remodeling							dph	2009-10-22T08:43:11Z					biological_process											owl:Class	
GO:0018648	biolink:NamedThing	methanesulfonate monooxygenase activity	Catalysis of the reaction: methanesulfonate + NADH + H+ + O2 = formaldehyde + NAD+ + sulfite + H2O.	tmpzr1t_l9r_go_relaxed.owl	methanesulfonate,FMNH2:oxygen oxidoreductase activity|methanesulfonic acid monooxygenase activity|MSAMO activity|methanesulphonic acid monooxygenase activity|methanesulfonate,NADH:oxygen oxidoreductase activity|MSA monooxygenase activity|mesylate monooxygenase activity				MetaCyc:RXN-9770|RHEA:26077|EC:1.14.13.111									molecular_function											owl:Class	
GO:1904408	biolink:NamedThing	melatonin binding	Binding to melatonin.	tmpzr1t_l9r_go_relaxed.owl								mr	2015-06-25T19:19:53Z					molecular_function											owl:Class	
GO:0019907	biolink:NamedThing	cyclin-dependent protein kinase activating kinase holoenzyme complex	A cyclin-dependent kinase activating kinase complex capable of activating cyclin-dependent kinases by threonine phosphorylation, thus regulating cell cycle progression. consists of a kinase, cyclin and optional assembly factors, in human CDK7, CCNH and MNAT1. CAK activity is itself regulated throughout the cell cycle by T-loop phosphorylation of its kinase component (CDK7 in human). Phosphorylation of serine residues during mitosis inactivates the enzyme. Also capable of CAK phosphorylating the carboxyl-terminal domain (CTD) of RNA polymerase II and other transcription activating proteins, as part of the general transcription factor TFIIH.	tmpzr1t_l9r_go_relaxed.owl	CDK-activating kinase complex|CAK complex													cellular_component											owl:Class	
GO:0002563	biolink:NamedThing	somatic diversification of immune receptors via alternate splicing	The process in which immune receptor genes are diversified through alternate splicing.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0008177	biolink:NamedThing	succinate dehydrogenase (ubiquinone) activity	Catalysis of the reaction: succinate + ubiquinone = fumarate + ubiquinol.	tmpzr1t_l9r_go_relaxed.owl	quinol:fumarate oxidoreductase activity|fumarate reductase complex (i.e. FRD, involved in anaerobic respiration, repressed in aerobic respiration)|succinate:ubiquinone oxidoreductase activity|succinate dehydrogenase complex (i. e. SDH, involved in aerobic respiration, repressed in anaerobic respiration)|respiratory complex II|menaquinol: fumarate oxidoreductase activity|succinic dehydrogenase activity				Reactome:R-HSA-70994|Reactome:R-HSA-163213|MetaCyc:SUCCINATE-DEHYDROGENASE-UBIQUINONE-RXN|RHEA:13713|EC:1.3.5.1|KEGG_REACTION:R02164							GO:0019737		molecular_function											owl:Class	
GO:0047696	biolink:NamedThing	beta-adrenergic receptor kinase activity	Catalysis of the reaction: ATP + beta-adrenergic receptor = ADP + phospho-beta-adrenergic receptor.	tmpzr1t_l9r_go_relaxed.owl	beta-adrenergic receptor-specific kinase activity|[b-adrenergic-receptor] kinase activity|beta-ARK 2|ATP:beta-adrenergic-receptor phosphotransferase activity|beta-adrenergic-receptor kinase (phosphorylating) activity|beta-AR kinase activity|betaARK1|STK15|beta-receptor kinase activity|beta2ARK|beta-ARK 1|beta-adrenoceptor kinase 1 activity|BARK1|ADRBK1|beta-adrenergic-receptor kinase activity|adrenergic receptor kinase activity|GRK3|GRK2|beta-ARK|beta-adrenoceptor kinase 2 activity|beta-adrenoceptor kinase activity				EC:2.7.11.15|Reactome:R-HSA-8851797|RHEA:19429|Reactome:R-HSA-8866268									molecular_function											owl:Class	
GO:0004828	biolink:NamedThing	serine-tRNA ligase activity	Catalysis of the reaction: ATP + L-serine + tRNA(Ser) = AMP + diphosphate + L-seryl-tRNA(Ser).	tmpzr1t_l9r_go_relaxed.owl	seryl-transfer ribonucleic acid synthetase activity|seryl-transfer RNA synthetase activity|L-serine:tRNASer ligase (AMP-forming)|seryl-tRNA synthetase activity|SerRS activity|serine translase activity|seryl-transfer ribonucleate synthetase activity				Reactome:R-HSA-380239|RHEA:12292|Reactome:R-HSA-379992|MetaCyc:SERINE--TRNA-LIGASE-RXN|EC:6.1.1.11									molecular_function											owl:Class	
GO:0160001	biolink:NamedThing	extrasynaptic signaling via GABA	Cell-cell signaling that starts with the activation of extrasynaptic GABA receptors in neurons through binding of ambient gamma-aminobutyric acid present in the extracellular fluid.	tmpzr1t_l9r_go_relaxed.owl								rl	2021-02-26T23:08:15Z					biological_process											owl:Class	
GO:1904590	biolink:NamedThing	negative regulation of protein import	Any process that stops, prevents or reduces the frequency, rate or extent of protein import.	tmpzr1t_l9r_go_relaxed.owl	down regulation of protein uptake|inhibition of protein import|inhibition of protein uptake|downregulation of protein uptake|negative regulation of protein uptake|down regulation of protein import|downregulation of protein import|down-regulation of protein import|down-regulation of protein uptake							sl	2015-08-20T21:26:36Z					biological_process											owl:Class	
GO:0052085	biolink:NamedThing	suppression by symbiont of host T-cell mediated immune response	Any process in which a symbiont stops, prevents, or reduces the frequency, rate or extent of the T-cell mediated immune response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	negative regulation by organism of T-cell mediated immune response of other organism involved in symbiotic interaction|inhibition by symbiont of host T-cell mediated immune response|negative regulation by symbiont of host T-cell mediated immune response|down regulation by symbiont of host T-cell mediated immune response|down-regulation by symbiont of host T-cell mediated immune response|downregulation by symbiont of host T-cell mediated immune response											GO:0052280		biological_process											owl:Class	
GO:0007317	biolink:NamedThing	regulation of pole plasm oskar mRNA localization	Any process that modulates the frequency, rate or extent of the process in which oskar mRNA is transported to, or maintained in, the oocyte pole plasm.	tmpzr1t_l9r_go_relaxed.owl	regulation of pole plasm oskar mRNA localisation|regulation of oocyte pole plasm oskar mRNA localization													biological_process											owl:Class	
GO:0106107	biolink:NamedThing	regulation of (R)-mevalonic acid biosynthetic process	Any process that modulates the frequency, rate or extent of (R)-mevalonic acid biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl								hjd	2018-03-27T14:08:59Z					biological_process											owl:Class	
GO:0070357	biolink:NamedThing	alphav-beta3 integrin-CD47 complex	A protein complex that consists of an alphav-beta3 integrin complex bound to CD47 (also known as IAP).	tmpzr1t_l9r_go_relaxed.owl	ITGB3-ITGAV-CD47 complex													cellular_component											owl:Class	
GO:0034879	biolink:NamedThing	2,3,6-trihydroxyisonicotinate decarboxylase activity	Catalysis of the reaction: 2,3,6-trihydroxyisonicotinate = 2,3,6-trihydroxypyridine + CO2.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r1340									molecular_function											owl:Class	
GO:0045982	biolink:NamedThing	negative regulation of purine nucleobase metabolic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving purine nucleobases.	tmpzr1t_l9r_go_relaxed.owl	downregulation of purine base metabolic process|negative regulation of purine base metabolic process|down-regulation of purine base metabolic process|negative regulation of purine base metabolism|inhibition of purine base metabolic process|down regulation of purine base metabolic process													biological_process											owl:Class	
GO:0050910	biolink:NamedThing	detection of mechanical stimulus involved in sensory perception of sound	The series of events involved in the perception of sound vibration in which the vibration is received and converted into a molecular signal.	tmpzr1t_l9r_go_relaxed.owl	perception of sound, sensory transduction of mechanical stimulus|perception of sound, detection of mechanical stimulus|sensory transduction of mechanical stimulus during perception of sound|sensory transduction of sound|perception of sound, sensory detection of mechanical stimulus|hearing, sensory transduction of sound|sensory detection of mechanical stimulus during perception of sound|detection of sound											GO:0009592|GO:0055128		biological_process											owl:Class	
GO:0080159	biolink:NamedThing	zygote elongation	The process in which the zygote irreversibly increases in size in one dimension after fertilization. An example of such a process is found in Arabidopsis thaliana.	tmpzr1t_l9r_go_relaxed.owl								dhl	2010-09-01T04:07:51Z					biological_process											owl:Class	
GO:0061822	biolink:NamedThing	ciliary cap	An intracellular compartmentalized cilium structure found in insect spermatids which is bounded by a membrane derived from the invagination of the cell membrane that remains associated with the primary cilium as it is internalized. The ciliary cap is maintained at the end of the axoneme distal to the centriole and is separated from the cytosolic axoneme/cytoplasm by a putative transition zone, which may extend into the ciliary cap, and include a structure at the base of the ciliary cap termed the ring centriole.	tmpzr1t_l9r_go_relaxed.owl	spermatid ciliary cap							dph	2017-01-14T14:14:11Z					cellular_component											owl:Class	
GO:0075110	biolink:NamedThing	induction by symbiont of host receptor-mediated signal transduction	Any process in which the symbiont activates, maintains or increases the frequency, rate or extent of receptor-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	positive regulation by symbiont of host receptor-mediated signal transduction					Note that this term is used to annotate gene products of the symbiont. To annotate host gene products, consider the biological process term "positive regulation by host of symbiont receptor-mediated signal transduction ; GO:0075079".								biological_process											owl:Class	
GO:0046214	biolink:NamedThing	enterobactin catabolic process	The chemical reactions and pathways resulting in the breakdown of enterobactin, a catechol-derived siderochrome of Enterobacteria; enterobactin (N',N',N''-(2,6,10-trioxo-1,5,9-triacyclodecane-3,7,11-triyl)tris(2,3-dihydroxy)benzamide) is a self-triester of 2,3-dihydroxy-N-benzoyl-L-serine and a product of the shikimate pathway.	tmpzr1t_l9r_go_relaxed.owl	enterobactin catabolism|enterobactin breakdown|enterobactin degradation													biological_process											owl:Class	
GO:0031979	biolink:NamedThing	plasma membrane-derived thylakoid lumen	The volume enclosed by a plasma membrane-derived thylakoid.	tmpzr1t_l9r_go_relaxed.owl	plasma membrane thylakoid lumen													cellular_component											owl:Class	
GO:1902780	biolink:NamedThing	response to nonane	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nonane stimulus.	tmpzr1t_l9r_go_relaxed.owl								tt	2014-03-21T03:24:50Z					biological_process											owl:Class	
GO:0043503	biolink:NamedThing	skeletal muscle fiber adaptation	Any process in which the skeletal muscle fibers change their phenotypic profiles in response to altered functional demands and a variety of signals. Muscle fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast.	tmpzr1t_l9r_go_relaxed.owl	skeletal myofiber plasticity|skeletal muscle fiber plasticity|skeletal muscle fibre plasticity|skeletal myofibre plasticity													biological_process											owl:Class	
GO:0008138	biolink:NamedThing	protein tyrosine/serine/threonine phosphatase activity	Catalysis of the reactions: protein serine + H2O = protein serine + phosphate; protein threonine phosphate + H2O = protein threonine + phosphate; and protein tyrosine phosphate + H2O = protein tyrosine + phosphate.	tmpzr1t_l9r_go_relaxed.owl	dual-specificity protein phosphatase	https://github.com/geneontology/go-ontology/issues/12183			Reactome:R-HSA-9652816|Reactome:R-HSA-5675373|Reactome:R-HSA-5675376	Note that this term applies only to free amino acids. Consider 'protein serine/threonine phosphatase activity' or 'protein tyrosine/serine/threonine phosphatase activity' if you want to annotate a protein phosphatase.								molecular_function											owl:Class	
GO:2000047	biolink:NamedThing	regulation of cell-cell adhesion mediated by cadherin	Any process that modulates the frequency, rate or extent of cell-cell adhesion mediated by cadherin.	tmpzr1t_l9r_go_relaxed.owl								jl	2010-08-20T12:56:44Z					biological_process											owl:Class	
GO:0030770	biolink:NamedThing	demethylmacrocin O-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine(1+) + demethylmacrocin = S-adenosyl-L-homocysteine + H(+) + macrocin.	tmpzr1t_l9r_go_relaxed.owl	demethylmacrocin methyltransferase activity|S-adenosyl-L-methionine:demethylmacrocin 2'''-O-methyltransferase activity				EC:2.1.1.102|RHEA:17573|KEGG_REACTION:R02859|MetaCyc:DEMETHYLMACROCIN-O-METHYLTRANSFERASE-RXN									molecular_function											owl:Class	
GO:0036321	biolink:NamedThing	ghrelin secretion	The regulated release of ghrelin from a cell. Ghrelin is a 28 amino acid hunger-stimulating peptide hormone.	tmpzr1t_l9r_go_relaxed.owl	pancreatic ghrelin secretion							bf	2012-09-04T14:16:43Z					biological_process											owl:Class	
GO:0071458	biolink:NamedThing	integral component of cytoplasmic side of endoplasmic reticulum membrane	The component of the endoplasmic reticulum membrane consisting of the gene products that penetrate only the cytoplasmic side of the membrane.	tmpzr1t_l9r_go_relaxed.owl	integral to cytosolic side of endoplasmic reticulum membrane|integral to cytosolic leaflet of endoplasmic reticulum membrane|integral to ER membrane, cytosolic side|integral to cytosolic side of ER membrane							mah	2009-12-17T01:43:33Z					cellular_component											owl:Class	
GO:0120206	biolink:NamedThing	photoreceptor distal connecting cilium	The distal region of the photoreceptor connecting cilium is structurally unique to the photoreceptor and is maintained by retina-specific protein, SPATA7, and its interacting partners RPGR and RPGRIP1. It is essential for photoreceptor sensory cilium stability.	tmpzr1t_l9r_go_relaxed.owl	photoreceptor DCC|DCC							krc	2019-05-10T22:54:05Z					cellular_component											owl:Class	
GO:0097747	biolink:NamedThing	RNA polymerase activity	Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1); the synthesis of RNA from ribonucleotide triphosphates in the presence of a nucleic acid template.	tmpzr1t_l9r_go_relaxed.owl								pr	2016-12-02T11:48:55Z					molecular_function											owl:Class	
GO:0090217	biolink:NamedThing	negative regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity	Any process that decreases the frequency, rate or extent of the catalysis of the reaction: ATP + 1-phosphatidyl-1D-myo-inositol 4-phosphate = ADP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate.	tmpzr1t_l9r_go_relaxed.owl								tb	2010-01-12T10:00:45Z					biological_process											owl:Class	
GO:0036435	biolink:NamedThing	K48-linked polyubiquitin modification-dependent protein binding	Binding to a protein upon poly-ubiquitination formed by linkages between lysine residues at position 48 in the target protein.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-5683077			bf	2013-09-18T14:51:06Z					molecular_function											owl:Class	
GO:0051448	biolink:NamedThing	gonadotropin-releasing hormone binding	Binding to gonadotropin-releasing hormone (GnRH), a peptide hormone responsible for the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) from the anterior pituitary. GnRH is synthesized and released by the hypothalamus.	tmpzr1t_l9r_go_relaxed.owl	gonadotrophin releasing hormone binding|GnRH binding													molecular_function											owl:Class	
GO:0150118	biolink:NamedThing	negative regulation of cell-substrate junction organization	Any process that stops, prevents or reduces the frequency, rate or extent of cell-substrate junction organization.	tmpzr1t_l9r_go_relaxed.owl								bc	2019-11-14T12:16:32Z					biological_process											owl:Class	
GO:0031818	biolink:NamedThing	P2Y9 nucleotide receptor binding	Binding to a P2Y9 nucleotide receptor.	tmpzr1t_l9r_go_relaxed.owl	P2Y9 nucleotide receptor ligand													molecular_function											owl:Class	
GO:0050456	biolink:NamedThing	cystine reductase activity	Catalysis of the reaction: 2 L-cysteine + NAD(+) = L-cystine + H(+) + NADH.	tmpzr1t_l9r_go_relaxed.owl	cystine reductase (NADH2)|NADH-dependent cystine reductase activity|cystine reductase (NADH) activity|NADH2:L-cystine oxidoreductase|NADH:L-cystine oxidoreductase activity|L-cysteine:NAD+ oxidoreductase				RHEA:20597|KEGG_REACTION:R00892|EC:1.8.1.6|MetaCyc:CYSTINE-REDUCTASE-NADH-RXN									molecular_function											owl:Class	
GO:0045225	biolink:NamedThing	negative regulation of CD4 production	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of CD4.	tmpzr1t_l9r_go_relaxed.owl	down regulation of CD4 biosynthetic process|down-regulation of CD4 biosynthetic process|negative regulation of CD4 formation|negative regulation of CD4 anabolism|inhibition of CD4 biosynthetic process|negative regulation of CD4 synthesis|negative regulation of CD4 biosynthesis|negative regulation of CD4 biosynthetic process|downregulation of CD4 biosynthetic process													biological_process											owl:Class	
GO:1903710	biolink:NamedThing	spermine transmembrane transport	The process in which spermine is transported across a membrane.	tmpzr1t_l9r_go_relaxed.owl								vw	2014-12-06T08:11:32Z					biological_process											owl:Class	
GO:0005278	biolink:NamedThing	acetylcholine:proton antiporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + acetylcholine(in) = H+(in) + acetylcholine(out).	tmpzr1t_l9r_go_relaxed.owl	acetylcholine:hydrogen antiporter activity													molecular_function											owl:Class	
GO:0018132	biolink:NamedThing	peptide cross-linking via L-cysteine oxazolecarboxylic acid	The chemical reactions and pathways resulting in the formation of a peptidyl serine-peptidyl cysteine cross-link by the condensation of a serine hydroxyl with the carbonyl of the preceding residue and alpha-beta dehydrogenation.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0238									biological_process											owl:Class	
GO:1905811	biolink:NamedThing	negative regulation of excitatory synapse pruning	Any process that stops, prevents or reduces the frequency, rate or extent of excitatory synapse pruning.	tmpzr1t_l9r_go_relaxed.owl	regulation of synapse removal|regulation of synapse elimination|down regulation of excitatory synapse disassembly|regulation of synapse disassembly|inhibition of excitatory synapse disassembly|downregulation of excitatory synapse disassembly|regulation of synapse clearance|down-regulation of excitatory synapse disassembly							tb	2017-01-12T02:38:36Z					biological_process											owl:Class	
GO:1905807	biolink:NamedThing	negative regulation of synapse pruning	Any process that stops, prevents or reduces the frequency, rate or extent of synapse pruning.	tmpzr1t_l9r_go_relaxed.owl	regulation of synapse clearance|down-regulation of synapse disassembly|regulation of synapse removal|inhibition of synapse disassembly|regulation of synapse elimination|regulation of synapse disassembly|down regulation of synapse disassembly|downregulation of synapse disassembly							tb	2017-01-11T22:03:24Z					biological_process											owl:Class	
GO:0015576	biolink:NamedThing	sorbitol transmembrane transporter activity	Enables the transfer of sorbitol from one side of a membrane to the other. Sorbitol, also known as glucitol, is the hexitol derived by the reduction of the aldehyde group of glucose.	tmpzr1t_l9r_go_relaxed.owl	glucitol permease activity|glucitol transporter activity|sorbitol permease activity											GO:0015587		molecular_function											owl:Class	
GO:0003224	biolink:NamedThing	left ventricular compact myocardium morphogenesis	The process in which the anatomical structures of cardiac left ventricular compact myocardium are generated and organized.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-10-13T10:43:36Z					biological_process											owl:Class	
GO:0140291	biolink:NamedThing	peptidyl-glutamate ADP-deribosylation	The removal of ADP-ribose from ADP-ribosylglutamate.	tmpzr1t_l9r_go_relaxed.owl								pg	2018-11-22T14:34:24Z					biological_process											owl:Class	
GO:0051725	biolink:NamedThing	protein de-ADP-ribosylation	The process of removing one or more ADP-ribose residues from a protein.	tmpzr1t_l9r_go_relaxed.owl	protein poly(ADP-ribose) catabolism|protein poly(ADP-ribose) degradation|removal of ADP-ribose from protein|protein poly(ADP-ribose) catabolic process|protein poly(ADP-ribose) hydrolysis|poly(ADP-ribose) removal from protein|protein amino acid de-ADP-ribosylation													biological_process											owl:Class	
GO:0033325	biolink:NamedThing	choline biosynthetic process via phosphoryl-ethanolamine	The chemical reactions and pathways resulting in the formation of choline (2-hydroxyethyltrimethylammonium), via the intermediate phosphoryl-ethanolamine.	tmpzr1t_l9r_go_relaxed.owl	choline biosynthesis via phosphoryl-ethanolamine|choline synthesis via phosphoryl-ethanolamine|choline formation via phosphoryl-ethanolamine|choline anabolism via phosphoryl-ethanolamine				MetaCyc:PWY-3385|MetaCyc:PWY-4762									biological_process											owl:Class	
GO:0042425	biolink:NamedThing	choline biosynthetic process	The chemical reactions and pathways resulting in the formation of choline (2-hydroxyethyltrimethylammonium), an amino alcohol that occurs widely in living organisms as a constituent of certain types of phospholipids and in the neurotransmitter acetylcholine.	tmpzr1t_l9r_go_relaxed.owl	choline synthesis|choline biosynthesis|choline formation|choline anabolism				MetaCyc:PWY-4762									biological_process											owl:Class	
GO:0060580	biolink:NamedThing	ventral spinal cord interneuron fate determination	The process in which a cell becomes capable of differentiating autonomously into a ventral spinal cord interneuron regardless of its environment; upon determination, the cell fate cannot be reversed. Ventral spinal cord interneurons are cells located in the ventral portion of the spinal cord that transmit signals between sensory and motor neurons and are required for reflexive responses.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-05-07T12:24:50Z					biological_process											owl:Class	
GO:0048664	biolink:NamedThing	neuron fate determination	The process in which a cell becomes capable of differentiating autonomously into a neuron regardless of its environment; upon determination, the cell fate cannot be reversed.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1901456	biolink:NamedThing	positive regulation of response to toluene	Any process that activates or increases the frequency, rate or extent of response to toluene.	tmpzr1t_l9r_go_relaxed.owl	activation of response to toluene|up-regulation of response to toluene|up regulation of response to toluene|upregulation of response to toluene							tt	2012-10-02T14:23:45Z					biological_process											owl:Class	
GO:0072346	biolink:NamedThing	cADPR-sensitive calcium-release channel activity	Enables the transmembrane transfer of a calcium ion by a channel that opens when cyclic adenosine diphosphate ribose (cADPR) has been bound by the channel complex or one of its constituent parts.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-11-10T01:10:51Z					molecular_function											owl:Class	
GO:0043258	biolink:NamedThing	laminin-9 complex	A laminin complex composed of alpha4, beta2 and gamma1 polypeptide chains.	tmpzr1t_l9r_go_relaxed.owl	laminin-421 complex													cellular_component											owl:Class	
GO:0033410	biolink:NamedThing	UAC codon-amino acid adaptor activity	A triplet codon-amino acid adaptor activity that recognizes a UAC codon.	tmpzr1t_l9r_go_relaxed.owl	tyrosine tRNA|TAC codon-amino acid adaptor activity					Note that in the standard genetic code, TAC codes for tyrosine.								molecular_function											owl:Class	
GO:0031295	biolink:NamedThing	T cell costimulation	The process of providing, via surface-bound receptor-ligand pairs, a second, antigen-independent, signal in addition to that provided by the T cell receptor to augment T cell activation.	tmpzr1t_l9r_go_relaxed.owl	T-cell co-stimulation|T cell co-stimulation|T-lymphocyte costimulation|T-cell costimulation|T lymphocyte costimulation													biological_process											owl:Class	
GO:0106042	biolink:NamedThing	negative regulation of GABA-A receptor activity	Any process that stops, prevents or reduces the frequency, rate or extent of GABA-A receptor activity.	tmpzr1t_l9r_go_relaxed.owl								hjd	2017-07-27T18:55:03Z					biological_process											owl:Class	
GO:0050150	biolink:NamedThing	o-pyrocatechuate decarboxylase activity	Catalysis of the reaction: 2,3-dihydroxybenzoate + H(+) = catechol + CO(2).	tmpzr1t_l9r_go_relaxed.owl	2,3-dihydroxybenzoic acid decarboxylase activity|2,3-dihydroxybenzoate decarboxylase activity|2,3-dihydroxybenzoate carboxy-lyase (catechol-forming)|2,3-dihydroxybenzoate carboxy-lyase activity|2,3-DHBA decarboxylase activity				RHEA:21492|MetaCyc:O-PYROCATECHUATE-DECARBOXYLASE-RXN|UM-BBD_reactionID:r0579|EC:4.1.1.46|KEGG_REACTION:R00821							GO:0018790		molecular_function											owl:Class	
GO:0042270	biolink:NamedThing	protection from natural killer cell mediated cytotoxicity	The process of protecting a cell from natural killer cell mediated cytotoxicity.	tmpzr1t_l9r_go_relaxed.owl	protection from NK cell mediated cell death|protection from natural killer cell mediated cell death|protection from natural killer cell mediated cell killing|protection from NK cell mediated cytotoxicity|protection from NK cell mediated cytolysis|protection from natural killer cell mediated cytolysis|protection from NK cell mediated cell killing													biological_process											owl:Class	
GO:1901837	biolink:NamedThing	negative regulation of transcription of nucleolar large rRNA by RNA polymerase I	Any process that stops, prevents or reduces the frequency, rate or extent of transcription of nuclear large rRNA transcript mediated by RNA polymerase I.	tmpzr1t_l9r_go_relaxed.owl	downregulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter|negative regulation of transcription of nuclear rRNA large Pol I transcript|inhibition of transcription of nuclear large rRNA transcript from RNA polymerase I promoter|down-regulation of transcription of nuclear rRNA large Pol I transcript|downregulation of transcription of nuclear rRNA large Pol I transcript|down regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter|inhibition of transcription of nuclear rRNA large Pol I transcript|down-regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter|down regulation of transcription of nuclear rRNA large Pol I transcript|negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter							sart	2013-01-23T10:16:31Z					biological_process											owl:Class	
GO:0102284	biolink:NamedThing	L-threo-sphinganine reductase activity	Catalysis of the reaction: L-threo-sphinganine + NADP <=> H+ + NADPH + 3-dehydrosphinganinium(1+).	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-12645									molecular_function											owl:Class	
GO:0021832	biolink:NamedThing	cell-cell adhesion involved in cerebral cortex tangential migration using cell-cell interactions	The attachment of cells to one another to form groups of cells involved in cerebral cortex tangential migration.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1904767	biolink:NamedThing	octanoic acid binding	Binding to octanoic acid.	tmpzr1t_l9r_go_relaxed.owl	caprylic acid binding							kmv	2015-10-27T21:11:49Z					molecular_function											owl:Class	
GO:0047593	biolink:NamedThing	6-acetylglucose deacetylase activity	Catalysis of the reaction: 6-acetyl-D-glucose + H(2)O = D-glucose + acetate + H(+).	tmpzr1t_l9r_go_relaxed.owl	6-acetyl-D-glucose acetylhydrolase activity|6-O-acetylglucose deacetylase activity				RHEA:18485|EC:3.1.1.33|KEGG_REACTION:R00327|MetaCyc:6-ACETYLGLUCOSE-DEACETYLASE-RXN									molecular_function											owl:Class	
GO:1905092	biolink:NamedThing	response to diosgenin	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diosgenin stimulus.	tmpzr1t_l9r_go_relaxed.owl								bc	2016-03-31T11:04:28Z					biological_process											owl:Class	
GO:0031104	biolink:NamedThing	dendrite regeneration	The regrowth of dendrites in response to their loss or damage.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1904845	biolink:NamedThing	cellular response to L-glutamine	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-glutamine stimulus.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-12-07T19:39:24Z					biological_process											owl:Class	
GO:0008389	biolink:NamedThing	coumarin 7-hydroxylase activity	Catalysis of the reaction: coumarin + O2 + NADPH + H+ = hydroxycoumarin + H2O + NADP+.	tmpzr1t_l9r_go_relaxed.owl	cytochrome P450 CYP2A5				Reactome:R-HSA-76453|Reactome:R-HSA-211881									molecular_function											owl:Class	
GO:0070048	biolink:NamedThing	endobrevin-SNAP-25-syntaxin-1a complex	A SNARE complex that contains endobrevin (VAMP8), SNAP-25, and syntaxin 1a (or orthologs thereof).	tmpzr1t_l9r_go_relaxed.owl	Stx1a-Snap25-Vamp8 complex|SNARE complex (Stx1a, Snap25, Vamp8)													cellular_component											owl:Class	
GO:0061659	biolink:NamedThing	ubiquitin-like protein ligase activity	Catalysis of the transfer of a ubiquitin-like protein (ULP) to a substrate protein via the reaction X-ULP + S --> X + S-ULP, where X is either an E2 or E3 enzyme, the X-ULP linkage is a thioester bond, and the S-ULP linkage is an isopeptide bond between the C-terminal glycine of ULP and the epsilon-amino group of lysine residues in the substrate.	tmpzr1t_l9r_go_relaxed.owl	small conjugating protein ligase activity|E3							dph	2014-11-06T13:46:23Z					molecular_function											owl:Class	
GO:0015778	biolink:NamedThing	hexuronide transport	The directed movement of hexuronide into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Hexuronides are any compound formed by combination of glycosidic linkage of a hydroxy compound (e.g. an alcohol or a saccharide) with the anomeric carbon atom of a hexuronate.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0102054	biolink:NamedThing	maleylpyruvate hydrolase activity	Catalysis of the reaction: 3-maleylpyruvate(2-) + H2O <=> H+ + maleate(2-) + pyruvate.	tmpzr1t_l9r_go_relaxed.owl					RHEA:47956|MetaCyc:RXN-10447|EC:3.7.1.23									molecular_function											owl:Class	
GO:0086026	biolink:NamedThing	atrial cardiac muscle cell to AV node cell signaling	Any process that mediates the transfer of information from an atrial cardiomyocyte to an AV node cell.	tmpzr1t_l9r_go_relaxed.owl	atrial cardiomyocyte to atrioventricular node cell signaling|atrial cardiomyocyte to AV node cell signalling|atrial cardiomyocyte to AV node cell signaling							tb	2011-11-11T02:02:14Z					biological_process											owl:Class	
GO:0098634	biolink:NamedThing	cell-matrix adhesion mediator activity	The binding by a cell-adhesion protein on the cell surface to an extracellular matrix component, to mediate adhesion of the cell to the extracellular matrix.	tmpzr1t_l9r_go_relaxed.owl	cell-matrix adhesion molecule|protein binding involved in cell-matrix adhesion													molecular_function											owl:Class	
GO:0002512	biolink:NamedThing	central T cell tolerance induction	Tolerance induction of T cells in the thymus.	tmpzr1t_l9r_go_relaxed.owl	central T-lymphocyte tolerance induction|central T-cell tolerance induction|central T lymphocyte tolerance induction													biological_process											owl:Class	
GO:0090640	biolink:NamedThing	phosphatidylcholine biosynthesis from sn-glycero-3-phosphocholine	The phosphatidylcholine biosynthetic process that involves the two-step acylation of sn-glycero-3-phosphocholine to a phosphatidylcholine.	tmpzr1t_l9r_go_relaxed.owl								tb	2015-04-23T15:56:12Z					biological_process											owl:Class	
GO:0050969	biolink:NamedThing	detection of chemical stimulus involved in magnetoreception	The series of events involved in magnetoception in which a chemical stimulus is received and converted into a molecular signal. It is believed that organisms such as birds and salamanders interpret product ratios in chemical reactions which involve transitions between different spin states.	tmpzr1t_l9r_go_relaxed.owl	magnetoreception, sensory transduction of chemical stimulus|magnetoreception, detection of chemical stimulus|sensory detection of chemical stimulus during magnetoreception|magnetoreception, sensory detection of chemical stimulus|magnetoception, sensory transduction of chemical stimulus|sensory transduction of chemical stimulus during magnetoreception													biological_process											owl:Class	
GO:0007014	biolink:NamedThing	actin ubiquitination	The modification of actin by addition of ubiquitin groups.	tmpzr1t_l9r_go_relaxed.owl	indirect flight muscle actin ubiquitination													biological_process											owl:Class	
GO:0015903	biolink:NamedThing	fluconazole transport	The directed movement of fluconazole into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Fluconazole is an antifungal drug used for oral candidiasis and cryptococcal meningitis; it is still under study for treatment of vaginal candidiasis and other fungal infections.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0021703	biolink:NamedThing	locus ceruleus development	The process whose specific outcome is the progression of the locus ceruleus over time, from its formation to the mature structure. The locus ceruleus is a dense cluster of neurons within the dorsorostral pons. This nucleus is the major location of neurons that release norepinephrine throughout the brain, and is responsible for physiological responses to stress and panic.	tmpzr1t_l9r_go_relaxed.owl	locus coeruleus development|locus caeruleus development													biological_process											owl:Class	
GO:0072562	biolink:NamedThing	blood microparticle	A phospholipid microvesicle that is derived from any of several cell types, such as platelets, blood cells, endothelial cells, or others, and contains membrane receptors as well as other proteins characteristic of the parental cell. Microparticles are heterogeneous in size, and are characterized as microvesicles free of nucleic acids.	tmpzr1t_l9r_go_relaxed.owl	cell membrane microparticle							mah	2011-01-28T11:50:56Z					cellular_component											owl:Class	
GO:1902507	biolink:NamedThing	thiazole synthase complex	A protein complex which is capable of thiazole synthase activity.	tmpzr1t_l9r_go_relaxed.owl								bhm	2013-11-14T16:19:28Z					cellular_component											owl:Class	
GO:0045965	biolink:NamedThing	negative regulation of ecdysteroid metabolic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving ecdysteroids.	tmpzr1t_l9r_go_relaxed.owl	down regulation of ecdysteroid metabolic process|negative regulation of ecdysteroid metabolism|down-regulation of ecdysteroid metabolic process|downregulation of ecdysteroid metabolic process|inhibition of ecdysteroid metabolic process													biological_process											owl:Class	
GO:0019704	biolink:NamedThing	peptidyl-L-cysteine S-myristoylation	The modification of peptidyl-cysteine to form peptidyl-S-myristoyl-L-cysteine.	tmpzr1t_l9r_go_relaxed.owl	peptidyl-S-myristoyl-L-cysteine synthesis from peptidyl-cysteine|peptidyl-S-myristoyl-L-cysteine formation from peptidyl-cysteine|peptidyl-S-myristoyl-L-cysteine anabolism from peptidyl-cysteine|peptidyl-S-myristoyl-L-cysteine biosynthetic process from peptidyl-cysteine				RESID:AA0307									biological_process											owl:Class	
GO:0050140	biolink:NamedThing	nitrate reductase (cytochrome) activity	Catalysis of the reaction: ferrocytochrome + nitrate = ferricytochrome + nitrite.	tmpzr1t_l9r_go_relaxed.owl	benzyl viologen-nitrate reductase activity|ferrocytochrome:nitrate oxidoreductase activity				RHEA:12909|MetaCyc:NITRATE-REDUCTASE-CYTOCHROME-RXN|EC:1.9.6.1									molecular_function											owl:Class	
GO:0016677	biolink:NamedThing	oxidoreductase activity, acting on a heme group of donors, nitrogenous group as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which a heme group acts as a hydrogen or electron donor and reduces a nitrogenous group.	tmpzr1t_l9r_go_relaxed.owl	oxidoreductase activity, acting on haem group of donors, nitrogenous group as acceptor				EC:1.9.6.-									molecular_function											owl:Class	
GO:0047583	biolink:NamedThing	4-methyloxaloacetate esterase activity	Catalysis of the reaction: 4-methoxy-2,4-dioxobutanoate + H(2)O = H(+) + methanol + oxaloacetate.	tmpzr1t_l9r_go_relaxed.owl	oxaloacetate-4-methyl-ester oxaloacetohydrolase activity				MetaCyc:4-METHYLOXALOACETATE-ESTERASE-RXN|EC:3.1.1.44|KEGG_REACTION:R01144|RHEA:10564									molecular_function											owl:Class	
GO:1990355	biolink:NamedThing	L-methionine salvage from methionine sulphoxide	The generation of L-methionine from methionine sulphoxide.	tmpzr1t_l9r_go_relaxed.owl	methionine salvage from methionine sulphoxide							al	2014-04-02T12:55:01Z					biological_process											owl:Class	
GO:0050082	biolink:NamedThing	maltose phosphorylase activity	Catalysis of the reaction: maltose + phosphate = D-glucose + beta-D-glucose 1-phosphate.	tmpzr1t_l9r_go_relaxed.owl	maltose:phosphate 1-beta-D-glucosyltransferase activity				EC:2.4.1.8|MetaCyc:MALTOSE-PHOSPHORYLASE-RXN|RHEA:21116									molecular_function											owl:Class	
GO:0006799	biolink:NamedThing	polyphosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of a polyphosphate, the anion or salt of polyphosphoric acid.	tmpzr1t_l9r_go_relaxed.owl	polyphosphate biosynthesis|polyphosphate synthesis|polyphosphate formation|polyphosphate anabolism													biological_process											owl:Class	
GO:0102044	biolink:NamedThing	3-chlorobenzoate-4,5-oxygenase activity	Catalysis of the reaction: 3-chlorobenzoate + O2 + a reduced electron acceptor <=> 3-chlorobenzoate-cis-4,5-diol + an oxidized electron acceptor.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-10421									molecular_function											owl:Class	
GO:0150110	biolink:NamedThing	negative regulation of cholesterol esterification	Any process that stops, prevents or reduces the frequency, rate or extent of cholesterol esterification.	tmpzr1t_l9r_go_relaxed.owl								bc	2019-07-23T15:34:42Z					biological_process											owl:Class	
GO:0052789	biolink:NamedThing	mannan 1,3-beta-mannosidase activity	Catalysis of the hydrolysis of (1->3)-beta-D-mannosidic linkages in mannans, releasing mannose.	tmpzr1t_l9r_go_relaxed.owl	exo-1,3-mannanase activity|exo-beta-1,3-mannase activity|exo-1,3-beta-mannanase activity|beta-1,3-mannan 3-mannanohydrolase activity|1,3-beta-D-mannan mannanohydrolase activity							ai	2011-10-04T01:11:41Z					molecular_function											owl:Class	
GO:0004567	biolink:NamedThing	beta-mannosidase activity	Catalysis of the hydrolysis of terminal, non-reducing beta-D-mannose residues in beta-D-mannosides.	tmpzr1t_l9r_go_relaxed.owl	beta-D-mannoside mannohydrolase activity|beta-mannoside mannohydrolase activity|mannanase activity|mannase activity|exo-beta-D-mannanase activity|beta-D-mannosidase activity				MetaCyc:3.2.1.25-RXN|Reactome:R-HSA-8853710|EC:3.2.1.25									molecular_function											owl:Class	
GO:1905583	biolink:NamedThing	cellular response to mannose	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mannose stimulus.	tmpzr1t_l9r_go_relaxed.owl								pga	2016-10-21T11:40:47Z					biological_process											owl:Class	
GO:1905582	biolink:NamedThing	response to mannose	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mannose stimulus.	tmpzr1t_l9r_go_relaxed.owl								pga	2016-10-21T11:40:40Z					biological_process											owl:Class	
GO:0070624	biolink:NamedThing	negative regulation of thiamine biosynthetic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of thiamine.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of thiamine synthesis|downregulation of thiamine biosynthetic process|negative regulation of thiamine biosynthesis|negative regulation of thiamine anabolism|down-regulation of thiamine biosynthetic process|negative regulation of thiamin biosynthetic process|inhibition of thiamine biosynthetic process|negative regulation of thiamine formation|down regulation of thiamine biosynthetic process							mah	2009-05-01T03:20:41Z					biological_process											owl:Class	
GO:0032323	biolink:NamedThing	lipoate catabolic process	The chemical reactions and pathways resulting in the breakdown of lipoate.	tmpzr1t_l9r_go_relaxed.owl	lipoic acid degradation|lipoic acid catabolism|lipoic acid breakdown													biological_process											owl:Class	
GO:0035803	biolink:NamedThing	egg coat formation	Construction of an egg coat, a specialized extracellular matrix that surrounds the ovum of animals. The egg coat provides structural support and can play an essential role in oogenesis, fertilization and early development.	tmpzr1t_l9r_go_relaxed.owl	zona pellucida assembly|ZP assembly|VE formation|vitelline envelope formation							bf	2011-04-19T01:48:43Z					biological_process											owl:Class	
GO:0071948	biolink:NamedThing	activation-induced B cell apoptotic process	B cell apoptotic process that occurs upon engagement of either the B cell receptor or CD40. Engagement of either receptor, but not both, leads to expression of fas or related receptors that make the B cell susceptible to fas-ligand mediated death.	tmpzr1t_l9r_go_relaxed.owl	activation-induced B-cell apoptosis|activated B cell apoptosis|activation-induced cell death of B cells|activation-induced B cell apoptosis|activation-induced cell death of B-lymphocytes|AICD|activation-induced cell death of B-cells|activation-induced cell death of B lymphocytes|antigen-driven apoptosis							mah	2010-10-06T02:47:46Z					biological_process											owl:Class	
GO:0047266	biolink:NamedThing	poly(ribitol-phosphate) beta-glucosyltransferase activity	Catalysis of the reaction: poly(ribitol phosphate) + UDP-D-glucose = beta-D-glucosylpoly(ribitol phosphate) + UDP.	tmpzr1t_l9r_go_relaxed.owl	UDP-glucose:poly(ribitol-phosphate) beta-D-glucosyltransferase activity|UDP-D-glucose polyribitol phosphate glucosyl transferase activity|UDPglucose:poly(ribitol-phosphate) beta-D-glucosyltransferase activity|uridine diphosphoglucose-poly(ribitol-phosphate) beta-glucosyltransferase activity|UDP-D-glucose:polyribitol phosphate glucosyl transferase activity|UDP glucose-poly(ribitol-phosphate) beta-glucosyltransferase activity				EC:2.4.1.53|RHEA:10068|MetaCyc:2.4.1.53-RXN									molecular_function											owl:Class	
GO:0051042	biolink:NamedThing	negative regulation of calcium-independent cell-cell adhesion	Any process that stops, prevents, or reduces the frequency, rate or extent of calcium-independent cell-cell adhesion.	tmpzr1t_l9r_go_relaxed.owl	downregulation of calcium-independent cell-cell adhesion|down regulation of calcium-independent cell-cell adhesion|inhibition of calcium-independent cell-cell adhesion|down-regulation of calcium-independent cell-cell adhesion													biological_process											owl:Class	
GO:0018571	biolink:NamedThing	2,3-dihydroxy-p-cumate dioxygenase activity	Catalysis of the reaction: 2,3-dihydroxy-p-cumate + O2 = 2-hydroxy-3-carboxy-6-oxo-7-methylocta-2,4-dienoate.	tmpzr1t_l9r_go_relaxed.owl	2,3-dihydroxy-p-cumate 3,4-dioxygenase|2,3-dihydroxy-p-cumate-3,4-dioxygenase				MetaCyc:RXN-666|RHEA:42568|UM-BBD_reactionID:r0397									molecular_function											owl:Class	
GO:0004960	biolink:NamedThing	thromboxane receptor activity	Combining with a thromboxane (TXA) to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	TXA receptor activity													molecular_function											owl:Class	
GO:0004954	biolink:NamedThing	prostanoid receptor activity	Combining with a prostanoid, any compound based on or derived from the prostanoate structure, to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0019492	biolink:NamedThing	proline salvage	Any process which produces the amino acid proline from derivatives of it, without de novo synthesis.	tmpzr1t_l9r_go_relaxed.owl	proline cycling													biological_process											owl:Class	
GO:0010665	biolink:NamedThing	regulation of cardiac muscle cell apoptotic process	Any process that modulates the rate or extent of cardiac cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a cardiac muscle cell and result in its death.	tmpzr1t_l9r_go_relaxed.owl	regulation of cardiac muscle cell apoptosis													biological_process											owl:Class	
GO:0033121	biolink:NamedThing	regulation of purine nucleotide catabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of purine nucleotides.	tmpzr1t_l9r_go_relaxed.owl	regulation of purine nucleotide degradation|regulation of purine nucleotide breakdown|regulation of purine nucleotide catabolism													biological_process											owl:Class	
GO:0070432	biolink:NamedThing	regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway	Any process that modulates the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing 2 (NOD2) pathway.	tmpzr1t_l9r_go_relaxed.owl	regulation of nucleotide-binding oligomerization domain containing 2 signalling pathway|regulation of NOD2 signaling pathway													biological_process											owl:Class	
GO:0034294	biolink:NamedThing	sexual spore wall assembly	The aggregation, arrangement and bonding together of a set of components to form a sexual spore wall, the specialized envelope lying outside the cell membrane of a spore derived from a product of meiosis.	tmpzr1t_l9r_go_relaxed.owl	sexual spore wall formation													biological_process											owl:Class	
GO:1902006	biolink:NamedThing	negative regulation of proline biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of proline biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	down regulation of proline synthesis|down-regulation of proline biosynthesis|downregulation of proline biosynthesis|inhibition of proline formation|down-regulation of proline anabolism|negative regulation of proline anabolism|downregulation of proline biosynthetic process|inhibition of proline biosynthesis|down regulation of proline biosynthesis|down regulation of proline anabolism|negative regulation of proline formation|downregulation of proline formation|inhibition of proline anabolism|downregulation of proline synthesis|down regulation of proline formation|inhibition of proline biosynthetic process|inhibition of proline synthesis|down-regulation of proline formation|downregulation of proline anabolism|down-regulation of proline synthesis|down regulation of proline biosynthetic process|negative regulation of proline biosynthesis|negative regulation of proline synthesis|down-regulation of proline biosynthetic process							tb	2013-03-21T21:48:12Z					biological_process											owl:Class	
GO:2000215	biolink:NamedThing	negative regulation of proline metabolic process	Any process that stops, prevents, or reduces the frequency, rate or extent of proline metabolic process.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of proline metabolism							mah	2010-11-03T02:45:24Z					biological_process											owl:Class	
GO:0061919	biolink:NamedThing	process utilizing autophagic mechanism	A cellular process involving delivery of a portion of the cytoplasm to lysosomes or to the plant or fungal vacuole that does not involve direct transport through the endocytic or vacuolar protein sorting (Vps) pathways. This process typically leads to degradation of the cargo; however, it can also be used to deliver resident proteins, such as in the cytoplasm-to-vacuole targeting (Cvt) pathway.	tmpzr1t_l9r_go_relaxed.owl								dph	2017-07-13T19:42:14Z					biological_process											owl:Class	
GO:2000660	biolink:NamedThing	negative regulation of interleukin-1-mediated signaling pathway	Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-1-mediated signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of IL-1 alpha-mediated signaling pathway|negative regulation of interleukin-1 beta-mediated signaling pathway|negative regulation of IL-1-mediated signaling pathway|negative regulation of interleukin-1-mediated signalling pathway|negative regulation of IL-1 beta-mediated signaling pathway|negative regulation of interleukin-1 alpha-mediated signaling pathway							dph	2011-05-03T07:13:37Z					biological_process											owl:Class	
GO:0022606	biolink:NamedThing	establishment of proximal/distal cell polarity	The specification and formation of the polarity of a cell along its proximal/distal axis.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0036288	biolink:NamedThing	response to ximelagatran	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ximelagatran stimulus.	tmpzr1t_l9r_go_relaxed.owl						Note that this term is in the subset of terms that should not be used for direct manual annotation of gene products. It was created to be used for cross-referencing by other ontologies. Direct annotations to this term may be amended during annotation QC.		bf	2012-07-16T05:03:56Z					biological_process											owl:Class	
GO:0032118	biolink:NamedThing	horsetail-astral microtubule organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the horsetail-astral array, a structure of astral microtubules that emanates from the spindle pole body during meiosis.	tmpzr1t_l9r_go_relaxed.owl	horsetail-astral microtubule organization and biogenesis|horsetail-astral microtubule organisation|horsetail-astral microtubule array organization													biological_process											owl:Class	
GO:2000207	biolink:NamedThing	negative regulation of ribosomal small subunit export from nucleus	Any process that stops, prevents, or reduces the frequency, rate or extent of ribosomal small subunit export from nucleus.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of 40S ribosomal subunit export from nucleus|negative regulation of ribosomal small subunit transport from nucleus to cytoplasm|negative regulation of ribosomal small subunit-nucleus export|negative regulation of ribosomal small subunit export out of nucleus|negative regulation of 30S ribosomal subunit export from nucleus|negative regulation of ribosomal small subunit export from cell nucleus							mah	2010-10-26T10:54:14Z					biological_process											owl:Class	
GO:0021937	biolink:NamedThing	cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation	The process that mediates the transfer of information from Purkinje cells to granule cell precursors resulting in an increase in rate of granule cell precursor cell proliferation.	tmpzr1t_l9r_go_relaxed.owl	Purkinje cell-granule cell precursor cell signalling involved in regulation of granule cell precursor cell proliferation													biological_process											owl:Class	
GO:0051654	biolink:NamedThing	establishment of mitochondrion localization	The directed movement of the mitochondrion to a specific location.	tmpzr1t_l9r_go_relaxed.owl	mitochondria positioning|establishment of mitochondria localization|mitochondrial migration|establishment of mitochondrion localisation|mitochondrion positioning													biological_process											owl:Class	
GO:0102965	biolink:NamedThing	alcohol-forming fatty acyl-CoA reductase activity	Catalysis of the reaction: 2 NADPH + 2 H+ + a long-chain acyl-CoA = coenzyme A + 2 NADP + a long-chain alcohol.	tmpzr1t_l9r_go_relaxed.owl					EC:1.2.1.84|MetaCyc:RXN-9344|RHEA:52716									molecular_function											owl:Class	
GO:0042432	biolink:NamedThing	indole biosynthetic process	The chemical reactions and pathways resulting in the formation of indole (2,3-benzopyrrole), the basis of many biologically active substances (e.g. serotonin, tryptophan).	tmpzr1t_l9r_go_relaxed.owl	indole anabolism|indole biosynthesis|indole synthesis|indole formation													biological_process											owl:Class	
GO:0042431	biolink:NamedThing	indole metabolic process	The chemical reactions and pathways involving indole (2,3-benzopyrrole), the basis of many biologically active substances (e.g. serotonin, tryptophan).	tmpzr1t_l9r_go_relaxed.owl	indole metabolism													biological_process											owl:Class	
GO:0002946	biolink:NamedThing	tRNA C5-cytosine methylation	The process whereby a cytosine in a tRNA is methylated at position 5 of the cytosine.	tmpzr1t_l9r_go_relaxed.owl	tRNA 5-methylcytosine biosynthesis							hjd	2012-12-07T14:23:13Z					biological_process											owl:Class	
GO:0008595	biolink:NamedThing	anterior/posterior axis specification, embryo	The specification of the anterior/posterior axis of the embryo by the products of genes expressed maternally and genes expressed in the zygote.	tmpzr1t_l9r_go_relaxed.owl	anterior/posterior axis determination, embryo													biological_process											owl:Class	
GO:0036481	biolink:NamedThing	intrinsic apoptotic signaling pathway in response to hydrogen peroxide	A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced in response to hydrogen peroxide (H2O2).	tmpzr1t_l9r_go_relaxed.owl	H2O2-induced intrinsic apoptotic signaling pathway|hydrogen peroxide-induced intrinsic apoptotic signaling pathway|hydrogen peroxide-induced apoptosis|intrinsic apoptotic signaling pathway in response to H2O2							bf	2014-08-14T13:19:21Z					biological_process											owl:Class	
GO:0035361	biolink:NamedThing	Cul8-RING ubiquitin ligase complex	A ubiquitin ligase complex in which a cullin from the Cul8 subfamily and a RING domain protein form the catalytic core. In S. cerevisiae, Mms1p acts as the adaptor protein and substrate specificity is conferred by any of a number of different proteins.	tmpzr1t_l9r_go_relaxed.owl								bf	2010-03-05T02:41:12Z					cellular_component											owl:Class	
GO:0022881	biolink:NamedThing	protein-N(PI)-phosphohistidine-N-acetylgalactosamine phosphotransferase system transporter activity	Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + N-acetylgalactosamine(out) = protein histidine + N-acetylgalactosamine phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.	tmpzr1t_l9r_go_relaxed.owl	N-acetylgalactosamine PTS transporter activity													molecular_function											owl:Class	
GO:0033551	biolink:NamedThing	monopolin complex	A protein complex required for clamping microtubule binding sites, ensuring orientation of sister kinetochores to the same pole (mono-orientation) during meiosis I. In the yeast S. cerevisiae this complex consists of Csm1p, Lrs4p, Hrr25p and Mam1p; in S. pombe Psc1 and Mde4 have been identified as subunits.	tmpzr1t_l9r_go_relaxed.owl	monopolin subcomplex Csm1/Lrs4|Pcs1/Mde4 complex													cellular_component											owl:Class	
GO:0034124	biolink:NamedThing	regulation of MyD88-dependent toll-like receptor signaling pathway	Any process that modulates the frequency, rate, or extent of MyD88-dependent toll-like receptor signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	regulation ofMyD88-dependent TLR signaling pathway|regulation ofMyD88-dependent toll-like receptor signalling pathway													biological_process											owl:Class	
GO:0042122	biolink:NamedThing	alginic acid catabolic process	The chemical reactions and pathways resulting in the breakdown of alginic acid, a hydrophilic polysaccharide occurring in, for example, the cell walls of brown algae (brown seaweeds).	tmpzr1t_l9r_go_relaxed.owl	alginate catabolism|alginic acid catabolism|alginic acid breakdown|alginic acid degradation|alginate catabolic process													biological_process											owl:Class	
GO:1904195	biolink:NamedThing	regulation of granulosa cell proliferation	Any process that modulates the frequency, rate or extent of granulosa cell proliferation.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-05-07T17:02:25Z					biological_process											owl:Class	
GO:0005294	biolink:NamedThing	neutral L-amino acid secondary active transmembrane transporter activity	Enables the transfer of a neutral L-amino acid from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters.	tmpzr1t_l9r_go_relaxed.owl	neutral L-amino acid porter activity													molecular_function											owl:Class	
GO:0070406	biolink:NamedThing	glutamine binding	Binding to glutamine, 2,5-diamino-5-oxopentanoic acid.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0015954	biolink:NamedThing	pyrimidine ribonucleotide interconversion	The chemical reactions and pathways by which a pyrimidine ribonucleotide is synthesized from another pyrimidine ribonucleotide.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0018137	biolink:NamedThing	peptide cross-linking via glycine thiazolecarboxylic acid	The chemical reactions and pathways resulting in the formation of a peptidyl cysteine-peptidyl glycine cross-link by the condensation of a cysteine thiol with the carbonyl of the preceding residue and alpha-beta dehydrogenation.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0241									biological_process											owl:Class	
GO:1904106	biolink:NamedThing	protein localization to microvillus	A process in which a protein is transported to, or maintained in, a location within a microvillus.	tmpzr1t_l9r_go_relaxed.owl	protein localisation in microvillus|protein localisation to microvillus|protein localization in microvillus							kmv	2015-04-01T18:14:41Z					biological_process											owl:Class	
GO:1904399	biolink:NamedThing	heparan sulfate binding	Binding to heparan sulfate.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-06-23T19:56:54Z					molecular_function											owl:Class	
GO:0048653	biolink:NamedThing	anther development	The process whose specific outcome is the progression of the anther over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0018271	biolink:NamedThing	biotin-protein ligase activity	Catalysis of the reaction: ATP + biotin + protein = AMP + diphosphate + biotin-protein.	tmpzr1t_l9r_go_relaxed.owl	biotin-apoprotein ligase activity				Reactome:R-HSA-9035988|Reactome:R-HSA-2993802|Reactome:R-HSA-3323184|MetaCyc:BIOTINLIG-RXN|Reactome:R-HSA-2993814|Reactome:R-HSA-4167511|EC:6.3.4.-|Reactome:R-HSA-9035987|Reactome:R-HSA-2993447|Reactome:R-HSA-9035990|Reactome:R-HSA-2993799							GO:0000106		molecular_function											owl:Class	
GO:0046220	biolink:NamedThing	pyridine biosynthetic process	The chemical reactions and pathways resulting in the formation of pyridine, a nitrogenous base (C5H5N) obtained from the distillation of bone oil or coal tar, and by the decomposition of certain alkaloids, as a colorless liquid with a peculiar pungent odor.	tmpzr1t_l9r_go_relaxed.owl	pyridine biosynthesis|pyridine formation|pyridine synthesis|pyridine anabolism													biological_process											owl:Class	
GO:0080040	biolink:NamedThing	positive regulation of cellular response to phosphate starvation	Any process that activates or increases the frequency, rate or extent of cellular response to phosphate starvation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0072670	biolink:NamedThing	mitochondrial tRNA threonylcarbamoyladenosine modification	The attachment of a carbonyl group and a threonine to the amino group of the adenine residue immediately 3' of the anticodon, in mitochondrial tRNAs that decode ANN codons (where N is any base).	tmpzr1t_l9r_go_relaxed.owl	mitochondrial tRNA t6A modification							mah	2011-02-18T11:34:35Z					biological_process											owl:Class	
GO:0002949	biolink:NamedThing	tRNA threonylcarbamoyladenosine modification	The attachment of a carbonyl group and a threonine to the amino group of the adenine residue immediately 3' of the anticodon, in tRNAs that decode ANN codons (where N is any base).	tmpzr1t_l9r_go_relaxed.owl	threonylcarbamoyladenosine biosynthesis|threonylcarbamoyladenosine formation|threonylcarbamoyladenosine biosynthetic process|threonylcarbamoyladenosine anabolism|t6A biosynthetic process|t6A biosynthesis|t6A tRNA modification|threonylcarbamoyladenosine synthesis							hjd	2014-09-19T10:15:27Z			GO:0070526		biological_process											owl:Class	
GO:0075285	biolink:NamedThing	sexual sporulation resulting in formation of a multicellular or syncytial spore	The formation of multicellular or syncytial spore via septations derived from meiosis. A multicellular or syncytial spore is a structure that can be used for dissemination, for survival of adverse conditions because of its heat and dessication resistance, and/or for reproduction.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0034293	biolink:NamedThing	sexual sporulation	The formation of spores derived from the products of meiosis.	tmpzr1t_l9r_go_relaxed.owl	meiotic sporulation|meiotic spore formation|sexual spore formation													biological_process											owl:Class	
GO:0047668	biolink:NamedThing	amygdalin beta-glucosidase activity	Catalysis of the reaction: (R)-amygdalin + H(2)O = (R)-prunasin + D-glucose.	tmpzr1t_l9r_go_relaxed.owl	amygdalin b-glucosidase activity|amygdalin beta-D-glucohydrolase activity|amygdalin hydrolase activity|amygdalin glucosidase activity|amygdalinase|(R)-amygdalin beta-glucosidase activity				RHEA:14177|KEGG_REACTION:R02985|MetaCyc:AMYGDALIN-BETA-GLUCOSIDASE-RXN|EC:3.2.1.117							GO:0080080		molecular_function											owl:Class	
GO:0046722	biolink:NamedThing	lactic acid secretion	The controlled release of lactic acid, 2-hydroxypropanoic acid, by a cell or a tissue.	tmpzr1t_l9r_go_relaxed.owl	lactate secretion													biological_process											owl:Class	
GO:0006738	biolink:NamedThing	nicotinamide riboside catabolic process	The chemical reactions and pathways resulting in the breakdown of nicotinamide riboside, the product of the formation of a glycosidic bond between ribose and nicotinamide.	tmpzr1t_l9r_go_relaxed.owl	nicotinamide riboside breakdown|nicotinamide riboside catabolism|N-ribosylnicotinamide catabolic process|nicotinamide riboside degradation													biological_process											owl:Class	
GO:0016185	biolink:NamedThing	synaptic vesicle budding from presynaptic endocytic zone membrane	Evagination of the presynaptic membrane, resulting in the formation of a new synaptic vesicle.	tmpzr1t_l9r_go_relaxed.owl	synaptic vesicle budding from pre-synaptic membrane|synaptic vesicle budding involved in synaptic vesicle endocytosis													biological_process											owl:Class	
GO:0070142	biolink:NamedThing	synaptic vesicle budding	Evagination of a membrane to form a synaptic vesicle.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0060082	biolink:NamedThing	eye blink reflex	The reflex process in which a mechanical stimulus applied to the eye elicits a response of the eyelid closing.	tmpzr1t_l9r_go_relaxed.owl	nictitating membrane reflex													biological_process											owl:Class	
GO:1900439	biolink:NamedThing	positive regulation of filamentous growth of a population of unicellular organisms in response to chemical stimulus	Any process that activates or increases the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to chemical stimulus.	tmpzr1t_l9r_go_relaxed.owl	upregulation of filamentous growth of a population of unicellular organisms in response to chemical stimulus|activation of filamentous growth of a population of unicellular organisms in response to chemical stimulus|up regulation of filamentous growth of a population of unicellular organisms in response to chemical stimulus|up-regulation of filamentous growth of a population of unicellular organisms in response to chemical stimulus							di	2012-04-25T05:55:35Z					biological_process											owl:Class	
GO:1903786	biolink:NamedThing	regulation of glutathione biosynthetic process	Any process that modulates the frequency, rate or extent of glutathione biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of glutathione anabolism|regulation of glutathione biosynthesis|regulation of glutathione synthesis|regulation of glutathione formation							bf	2015-01-08T17:14:49Z					biological_process											owl:Class	
GO:0031342	biolink:NamedThing	negative regulation of cell killing	Any process that stops, prevents, or reduces the frequency, rate or extent of cell killing.	tmpzr1t_l9r_go_relaxed.owl	down regulation of cell killing|down-regulation of cell killing|downregulation of cell killing|inhibition of cell killing													biological_process											owl:Class	
GO:0001773	biolink:NamedThing	myeloid dendritic cell activation	The change in morphology and behavior of a dendritic cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0060473	biolink:NamedThing	cortical granule	A secretory vesicle that is stored under the cell membrane of an egg. These vesicles fuse with the egg plasma membrane as part of egg activation and are part of the block to polyspermy.	tmpzr1t_l9r_go_relaxed.owl	cortical vesicle													cellular_component											owl:Class	
GO:0102646	biolink:NamedThing	14betaH-scalarane-17alpha-19-diol synthase activity	Catalysis of the reaction: 14betaH-scalarane-17alpha-19-diol <=> all-trans-geranylfarnesol + H2O.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-15759									molecular_function											owl:Class	
GO:0050413	biolink:NamedThing	D-alanine 2-hydroxymethyltransferase activity	Catalysis of the reaction: 5,10-methylenetetrahydrofolate + D-alanine + H(2)O = (6S)-5,6,7,8-tetrahydrofolate + 2-methylserine.	tmpzr1t_l9r_go_relaxed.owl	5,10-methylenetetrahydrofolate:D-alanine 2-hydroxymethyltransferase activity|2-methylserine hydroxymethyltransferase activity|D-alanine hydroxymethyltransferase activity				EC:2.1.2.7|KEGG_REACTION:R01225|MetaCyc:D-ALANINE-HYDROXYMETHYLTRANSFERASE-RXN|RHEA:10064									molecular_function											owl:Class	
GO:0010715	biolink:NamedThing	regulation of extracellular matrix disassembly	Any process that modulates the rate, frequency or extent of extracellular matrix disassembly. Extracellular matrix disassembly is a process that results in the breakdown of the extracellular matrix.	tmpzr1t_l9r_go_relaxed.owl	regulation of extracellular matrix breakdown|regulation of extracellular matrix degradation													biological_process											owl:Class	
GO:0046064	biolink:NamedThing	dCMP biosynthetic process	The chemical reactions and pathways resulting in the formation of dCMP, deoxycytidine monophosphate.	tmpzr1t_l9r_go_relaxed.owl	dCMP anabolism|dCMP synthesis|dCMP formation|dCMP biosynthesis													biological_process											owl:Class	
GO:0070587	biolink:NamedThing	regulation of cell-cell adhesion involved in gastrulation	Any process that modulates the frequency, rate, or extent of attachment of a cell to another cell affecting gastrulation.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-04-24T02:51:07Z					biological_process											owl:Class	
GO:0016935	biolink:NamedThing	glycine-gated chloride channel complex	A protein complex that forms a transmembrane channel through which chloride ions may pass in response to glycine binding to the channel complex or one of its constituent parts.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:1901223	biolink:NamedThing	negative regulation of NIK/NF-kappaB signaling	Any process that stops, prevents or reduces the frequency, rate or extent of NIK/NF-kappaB signaling.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of p52-dependent NF-kappaB signaling|down regulation of NIK/NF-kappaB cascade|down-regulation of noncanonical NF-kappaB signaling|negative regulation of non-canonical NF-KB signaling|negative regulation of noncanonical nuclear factor kappaB (NF-kappaB) pathway|inhibition of p52-dependent NF-kappaB signaling|negative regulation of NF-kappaB import into nucleus|downregulation of non-canonical NF-KB signaling|down regulation of noncanonical nuclear factor kappaB (NF-kappaB) pathway|down regulation of noncanonical NF-kappaB signaling|down regulation of non-canonical NF-KB signaling|downregulation of NIK/NF-kappaB cascade|negative regulation of noncanonical NF-kappaB signaling|down-regulation of noncanonical nuclear factor kappaB (NF-kappaB) pathway|inhibition of noncanonical NF-kappaB signaling|negative regulation of NIK/NF-kappaB cascade|down regulation of p52-dependent NF-kappaB signaling|inhibition of NIK/NF-kappaB cascade|down-regulation of NIK/NF-kappaB cascade|downregulation of noncanonical NF-kappaB signaling|inhibition of noncanonical nuclear factor kappaB (NF-kappaB) pathway|down-regulation of p52-dependent NF-kappaB signaling|inhibition of non-canonical NF-KB signaling|down-regulation of non-canonical NF-KB signaling|downregulation of p52-dependent NF-kappaB signaling|downregulation of noncanonical nuclear factor kappaB (NF-kappaB) pathway							hjd	2012-08-06T20:27:39Z			GO:0042347		biological_process											owl:Class	
GO:0019715	biolink:NamedThing	peptidyl-aspartic acid hydroxylation to form L-erythro-beta-hydroxyaspartic acid	The hydroxylation of peptidyl-aspartic acid to form peptidyl-L-erythro-beta-hydroxyaspartic acid; catalyzed by peptide-aspartate beta-dioxygenase (EC:1.14.11.16).	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0027	See also the molecular function term 'peptide-aspartate beta-dioxygenase activity ; GO:0004597'.								biological_process											owl:Class	
GO:0042264	biolink:NamedThing	peptidyl-aspartic acid hydroxylation	The hydroxylation of peptidyl-aspartic acid to form peptidyl-hydroxyaspartic acid.	tmpzr1t_l9r_go_relaxed.owl	peptidyl-aspartic acid/asparagine hydroxylation													biological_process											owl:Class	
GO:0031282	biolink:NamedThing	regulation of guanylate cyclase activity	Any process that modulates the frequency, rate or extent of guanylate cyclase activity.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0000961	biolink:NamedThing	negative regulation of mitochondrial RNA catabolic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving catabolism in the mitochondrion of RNA transcribed from the mitochondrial genome.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0102928	biolink:NamedThing	beta-solanine rhamnosyltransferase activity	Catalysis of the reaction: beta-solanine + UDP-L-rhamnose = solanine + UDP.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-8884									molecular_function											owl:Class	
GO:1904632	biolink:NamedThing	cellular response to glucoside	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucoside stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to glucosides							sl	2015-08-28T14:01:37Z					biological_process											owl:Class	
GO:0008996	biolink:NamedThing	ribonuclease G activity	Catalysis of the cleavage of single-stranded RNA that is monophosphorylated at its 5'-end; cleavage occurs predominantly at positions 5 and 6 nucleotides from the 5'-end and in A + U-rich regions, and is blocked by the presence of a 5'-triphosphate group.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0036068	biolink:NamedThing	light-independent chlorophyll biosynthetic process	The chemical reactions and pathways resulting in the formation of chlorophyll, any compound of magnesium complexed in a porphyrin (tetrapyrrole) ring and which functions as a photosynthetic pigment, from less complex precursors, which occur in the absence of light.	tmpzr1t_l9r_go_relaxed.owl	light-independent chlorophyll biosynthesis|light-independent chlorophyll formation|light-independent chlorophyll synthesis|light independent chlorophyll biosynthetic process|light-independent chlorophyll anabolism							bf	2011-12-15T04:44:18Z					biological_process											owl:Class	
GO:0044102	biolink:NamedThing	purine deoxyribosyltransferase activity	Catalysis of deoxyribose exchange between purine deoxyribonucleoside as a donor and purine base as an acceptor.	tmpzr1t_l9r_go_relaxed.owl	PTD|purine 2'-deoxyribosyltransferase activity							jl	2009-07-09T03:40:15Z					molecular_function											owl:Class	
GO:0140340	biolink:NamedThing	cerebroside transfer activity	Directly binding to a cerebroside and delivering it either to an acceptor molecule or to a specific location.	tmpzr1t_l9r_go_relaxed.owl	cerebroside carrier activity							pg	2019-05-16T11:37:31Z					molecular_function											owl:Class	
GO:1900036	biolink:NamedThing	positive regulation of cellular response to heat	Any process that activates or increases the frequency, rate or extent of cellular response to heat.	tmpzr1t_l9r_go_relaxed.owl	up regulation of cellular response to heat stress|up-regulation of cellular response to heat stress|upregulation of cellular response to heat|activation of cellular response to heat|positive regulation of cellular response to heat stress|activation of cellular response to heat stress|up-regulation of cellular response to heat|up regulation of cellular response to heat|upregulation of cellular response to heat stress							yaf	2012-01-17T09:27:47Z					biological_process											owl:Class	
GO:0102902	biolink:NamedThing	isopimaradienal hydroxylase activity	Catalysis of the reaction: isopimaradienal + NADPH + O2 <=> isopimaric acid + NADP + H2O.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-8538									molecular_function											owl:Class	
GO:0010094	biolink:NamedThing	specification of carpel identity	The process in which a floral organ primordium acquires the carpel identity. Identity is considered to be the aggregate of characteristics by which a structure is recognized.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0150061	biolink:NamedThing	amylin receptor 3 signaling pathway	A series of molecular signals initiated by an extracellular amylin, or another ligand, combining with an amylin receptor 3 (AMY3), a G protein-coupled receptor complex, on the surface of the target cell. The AMY3 signaling pathway can also be initiated by the amyloid-beta complex. AMY3 signaling results in increased import of calcium ions into the cytosol across plasma membrane, increased phosphorylation of ERK1/2, Act, and a PKA regulatory subunit II, as well as increased expression of cFos.	tmpzr1t_l9r_go_relaxed.owl	AMY3 signaling pathway							bc	2018-06-21T11:02:09Z					biological_process											owl:Class	
GO:0097647	biolink:NamedThing	amylin receptor signaling pathway	A series of molecular signals initiated by an extracellular amylin combining with a dimeric amylin receptor on the surface of the target cell.	tmpzr1t_l9r_go_relaxed.owl	amilyn receptor signalling pathway							pr	2014-09-09T17:49:52Z					biological_process											owl:Class	
GO:0090546	biolink:NamedThing	chlorophyll fluorescence	The process by which excess light energy absorbed by chlorophyll and not used to drive photosynthesis is re-emitted as light.	tmpzr1t_l9r_go_relaxed.owl								tb	2013-03-27T14:23:27Z					biological_process											owl:Class	
GO:0010759	biolink:NamedThing	positive regulation of macrophage chemotaxis	Any process that increases the rate, frequency or extent of macrophage chemotaxis. Macrophage chemotaxis is the movement of a macrophage in response to an external stimulus.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0044481	biolink:NamedThing	envenomation resulting in proteolysis in other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant hydrolysis of proteins in of the bitten organism.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-01-19T03:01:16Z					biological_process											owl:Class	
GO:1990192	biolink:NamedThing	collecting lymphatic vessel constriction	A decrease in the diameter of collecting lymphatic vessels.	tmpzr1t_l9r_go_relaxed.owl	lymphatic vessel myogenic constriction							sl	2013-09-12T14:46:05Z					biological_process											owl:Class	
GO:0050008	biolink:NamedThing	isopiperitenone delta-isomerase activity	Catalysis of the reaction: isopiperitenone = piperitenone.	tmpzr1t_l9r_go_relaxed.owl	isopiperitenone delta8-delta4-isomerase activity|isopiperitenone D-isomerase activity				RHEA:21516|KEGG_REACTION:R03782|EC:5.3.3.11|MetaCyc:ISOPIPERITENONE-DELTA-ISOMERASE-RXN									molecular_function											owl:Class	
GO:0010111	biolink:NamedThing	glyoxysome organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the glyoxysome. A glyoxysome is a microbody that contains the enzymes of the glyoxylate pathway.	tmpzr1t_l9r_go_relaxed.owl	glyoxysome organisation|glyoxysome organization and biogenesis													biological_process											owl:Class	
GO:0070700	biolink:NamedThing	BMP receptor binding	Binding to a BMP receptor.	tmpzr1t_l9r_go_relaxed.owl	bone morphogenetic protein receptor binding							mah	2009-06-04T04:24:16Z					molecular_function											owl:Class	
GO:0070696	biolink:NamedThing	transmembrane receptor protein serine/threonine kinase binding	Binding to a receptor that spans a cell membrane and possesses protein serine/threonine kinase activity.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-06-04T03:57:42Z					molecular_function											owl:Class	
GO:0150164	biolink:NamedThing	miRNA-mediated regulation of transcription by RNA polymerase II	Any process mediated by a microRNA (miRNA) that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter.	tmpzr1t_l9r_go_relaxed.owl								bc	2020-01-14T12:16:32Z					biological_process											owl:Class	
GO:0045933	biolink:NamedThing	positive regulation of muscle contraction	Any process that activates or increases the frequency, rate or extent of muscle contraction.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of muscle contraction|upregulation of muscle contraction|stimulation of muscle contraction|up regulation of muscle contraction|activation of muscle contraction													biological_process											owl:Class	
GO:0097179	biolink:NamedThing	protease inhibitor complex	A heterodimeric protein complex that contains a protease inhibitor and a protease; formation of the complex inhibits protease activity.	tmpzr1t_l9r_go_relaxed.owl	peptidase inhibitor complex							pr	2011-10-16T08:53:44Z					cellular_component											owl:Class	
GO:0098716	biolink:NamedThing	nickel cation import across plasma membrane	The directed movement of nickel cations from outside of a cell, across the plasma membrane and into the cytosol.	tmpzr1t_l9r_go_relaxed.owl	nickel cation import into cell							tb	2012-11-16T16:12:53Z			GO:0090509		biological_process											owl:Class	
GO:0018306	biolink:NamedThing	iron incorporation into iron-sulfur cluster via bis-L-cysteinyl-L-N3'-histidino-L-serinyl tetrairon tetrasulfide	The incorporation of iron into a 4Fe-4S iron-sulfur cluster via bis-L-cysteinyl-L-N3'-histidino-L-serinyl tetrairon tetrasulfide.	tmpzr1t_l9r_go_relaxed.owl	iron incorporation into iron-sulphur cluster via bis-L-cysteinyl-L-N3'-histidino-L-serinyl tetrairon tetrasulphide				RESID:AA0289									biological_process											owl:Class	
GO:1900115	biolink:NamedThing	extracellular regulation of signal transduction	Any regulation of signal transduction that takes place in the extracellular region.	tmpzr1t_l9r_go_relaxed.owl	regulation of signalling pathway in extracellular region|regulation of signaling pathway in extracellular region							bf	2012-02-22T10:21:48Z					biological_process											owl:Class	
GO:0048675	biolink:NamedThing	axon extension	Long distance growth of a single axon process involved in cellular development.	tmpzr1t_l9r_go_relaxed.owl	axon extension involved in development											GO:0048676		biological_process											owl:Class	
GO:0044229	biolink:NamedThing	host cell periplasmic space	The region between the inner (cytoplasmic) and outer host membrane (Gram-negative Bacteria) or inner host membrane and host cell wall (Fungi).	tmpzr1t_l9r_go_relaxed.owl								jl	2009-12-03T01:52:31Z					cellular_component											owl:Class	
GO:1901052	biolink:NamedThing	sarcosine metabolic process	The chemical reactions and pathways involving sarcosine.	tmpzr1t_l9r_go_relaxed.owl	sarcosine metabolism							yaf	2012-06-28T04:52:04Z					biological_process											owl:Class	
GO:0033897	biolink:NamedThing	ribonuclease T2 activity	Catalysis of the two-stage endonucleolytic cleavage to nucleoside 3'-phosphates and 3'-phosphooligonucleotides with 2',3'-cyclic phosphate intermediates.	tmpzr1t_l9r_go_relaxed.owl	ribonuclease (non-base specific) activity|RNase T2 activity|Escherichia coli ribonuclease I' ribonuclease PP2 activity|RNase (non-base specific) activity|acid RNase activity|ribonuclease M activity|non-base specific ribonuclease activity|RNase II activity|RNAase CL activity|ribonnuclease (non-base specific) activity|nonbase-specific RNase activity|ribonuclease II activity|RNase M activity|ribonucleate nucleotido-2'-transferase (cyclizing) activity|ribonuclease N2 activity|ribonuclease U4 activity|base-non-specific ribonuclease activity|acid ribonuclease activity|Escherichia coli ribonuclease II activity|RNase Ms activity|nonspecific RNase activity|ribonuclease PP3 activity|ribonucleate 3'-oligonucleotide hydrolase activity				MetaCyc:3.1.27.1-RXN|EC:4.6.1.19									molecular_function											owl:Class	
GO:0046144	biolink:NamedThing	D-alanine family amino acid metabolic process	The chemical reactions and pathways involving D-alanine and related amino acids.	tmpzr1t_l9r_go_relaxed.owl	D-alanine family amino acid metabolism													biological_process											owl:Class	
GO:0036393	biolink:NamedThing	thiocyanate peroxidase activity	Catalysis of the reaction: thiocyanate (SCN-) + hydrogen peroxide (H2O2) = hypothiocyanite (OSCN-) + 2 H2O. Catalyzes the hydrogen peroxide oxidation of thiocyanate.	tmpzr1t_l9r_go_relaxed.owl	lactoperoxidase activity							bf	2013-06-20T16:03:57Z					molecular_function											owl:Class	
GO:1901181	biolink:NamedThing	negative regulation of cellular response to caffeine	Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to caffeine.	tmpzr1t_l9r_go_relaxed.owl	down regulation of cellular response to caffeine|down-regulation of cellular response to caffeine|inhibition of cellular response to caffeine|downregulation of cellular response to caffeine							al	2012-07-19T04:11:46Z					biological_process											owl:Class	
GO:1901765	biolink:NamedThing	phosphinothricin catabolic process	The chemical reactions and pathways resulting in the breakdown of phosphinothricin.	tmpzr1t_l9r_go_relaxed.owl	phosphinothricin catabolism|phosphinothricin breakdown|phosphinothricin degradation							yaf	2013-01-15T10:02:42Z					biological_process											owl:Class	
GO:1902257	biolink:NamedThing	negative regulation of apoptotic process involved in outflow tract morphogenesis	Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic process involved in outflow tract morphogenesis.	tmpzr1t_l9r_go_relaxed.owl	inhibition of apoptotic process involved in outflow tract morphogenesis|down-regulation of apoptotic process involved in outflow tract morphogenesis|down regulation of apoptosis involved in outflow tract morphogenesis|down regulation of apoptotic process involved in outflow tract morphogenesis|down-regulation of apoptosis involved in outflow tract morphogenesis|downregulation of apoptosis involved in outflow tract morphogenesis|negative regulation of apoptosis involved in outflow tract morphogenesis|inhibition of apoptosis involved in outflow tract morphogenesis|downregulation of apoptotic process involved in outflow tract morphogenesis							dph	2013-06-24T19:12:30Z					biological_process											owl:Class	
GO:1903255	biolink:NamedThing	hercynylselenocysteine biosynthetic process	The chemical reactions and pathways resulting in the formation of hercynylselenocysteine.	tmpzr1t_l9r_go_relaxed.owl	hercynylselenocysteine biosynthesis|hercynylselenocysteine anabolism|hercynylselenocysteine formation|hercynylselenocysteine synthesis							mah	2014-08-06T09:14:16Z					biological_process											owl:Class	
GO:0038159	biolink:NamedThing	C-X-C chemokine receptor CXCR4 signaling pathway	A series of molecular signals initiated by a the C-X-C chemokine type 4 receptor on the surface of a cell binding to one of it's physiological ligands, and ending with regulation of a downstream cellular process, e.g. transcription.	tmpzr1t_l9r_go_relaxed.owl	CXCR4 signaling pathway							bf	2012-05-14T01:33:17Z					biological_process											owl:Class	
GO:0019511	biolink:NamedThing	peptidyl-proline hydroxylation	The hydroxylation of peptidyl-proline to form peptidyl-hydroxyproline.	tmpzr1t_l9r_go_relaxed.owl												GO:0006472		biological_process											owl:Class	
GO:0008147	biolink:NamedThing	structural constituent of bone	The action of a molecule that contributes to the structural integrity of bone.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0018162	biolink:NamedThing	peptide cross-linking via S-(2-aminovinyl)-3-methyl-D-cysteine	The formation of a cross-link between peptidyl-cysteine and peptidyl-threonine via the formation of S-(2-aminovinyl)-3-methyl-D-cysteine.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0253									biological_process											owl:Class	
GO:0047407	biolink:NamedThing	ADP-ribosyl-[dinitrogen reductase] hydrolase activity	Catalysis of the reaction: ADP-ribosyl-[dinitrogen reductase] = adenosine diphosphate ribose + [dinitrogen reductase].	tmpzr1t_l9r_go_relaxed.owl	azoferredoxin glycosidase activity|ADP-D-ribosyl-dinitrogen reductase ADP-ribosylhydrolase activity|ADP-ribosyl-dinitrogen reductase hydrolase activity|dinitrogenase reductase-activating glycohydrolase activity|azoferredoxin-activating enzymes|dinitrogenase reductase activating glycohydrolase activity|ADP-ribosyl glycohydrolase activity				EC:3.2.2.24|RHEA:14493|MetaCyc:3.2.2.24-RXN									molecular_function											owl:Class	
GO:0002123	biolink:NamedThing	irritable aggressive behavior	Aggressive behavior induced by frustration and directed against an available target.	tmpzr1t_l9r_go_relaxed.owl	irritable aggression													biological_process											owl:Class	
GO:1990253	biolink:NamedThing	cellular response to leucine starvation	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of leucine.	tmpzr1t_l9r_go_relaxed.owl								al	2013-12-10T11:55:10Z					biological_process											owl:Class	
GO:0047166	biolink:NamedThing	1-alkenylglycerophosphoethanolamine O-acyltransferase activity	Catalysis of the reaction: 1-alkenylglycerophosphoethanolamine + acyl-CoA = 1-alkenyl-2-acyl-glycerophosphoethanolamine + CoA.	tmpzr1t_l9r_go_relaxed.owl	acyl-CoA:1-alkenylglycerophosphoethanolamine O-acyltransferase activity				EC:2.3.1.121|MetaCyc:2.3.1.121-RXN|RHEA:16245									molecular_function											owl:Class	
GO:0031014	biolink:NamedThing	troponin T binding	Binding to troponin T, the tropomyosin-binding subunit of the troponin complex.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0047676	biolink:NamedThing	arachidonate-CoA ligase activity	Catalysis of the reaction: arachidonate + ATP + CoA = AMP + arachidonoyl-CoA + diphosphate + H(+).	tmpzr1t_l9r_go_relaxed.owl	arachidonate:CoA ligase (AMP-forming)|arachidonoyl-CoA synthetase activity				EC:6.2.1.15|KEGG_REACTION:R01598|RHEA:19713|MetaCyc:ARACHIDONATE--COA-LIGASE-RXN									molecular_function											owl:Class	
GO:0050399	biolink:NamedThing	xanthommatin reductase activity	Catalysis of the reaction: 5,12-dihydroxanthommatin + NAD(+) = H(+) + NADH + xanthommatin.	tmpzr1t_l9r_go_relaxed.owl	5,12-dihydroxanthommatin:NAD+ oxidoreductase activity				EC:1.3.1.41|RHEA:13417|MetaCyc:XANTHOMMATIN-REDUCTASE-RXN|KEGG_REACTION:R03787									molecular_function											owl:Class	
GO:0042777	biolink:NamedThing	plasma membrane ATP synthesis coupled proton transport	The transport of protons across the plasma membrane to generate an electrochemical gradient (proton-motive force) that powers ATP synthesis.	tmpzr1t_l9r_go_relaxed.owl	ATP synthesis coupled proton transport													biological_process											owl:Class	
GO:0043995	biolink:NamedThing	histone acetyltransferase activity (H4-K5 specific)	Catalysis of the reaction: acetyl-CoA + histone H4 L-lysine (position 5) = CoA + histone H4 N6-acetyl-L-lysine (position 5).	tmpzr1t_l9r_go_relaxed.owl	histone lysine N-acetyltransferase activity (H4-K5 specific)													molecular_function											owl:Class	
GO:0022018	biolink:NamedThing	lateral ganglionic eminence cell proliferation	The multiplication or reproduction of lateral ganglionic eminence cells, resulting in the expansion of the cell population.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0060431	biolink:NamedThing	primary lung bud formation	The morphogenetic process in which the foregut region specified to become the lung forms the initial left and right buds.	tmpzr1t_l9r_go_relaxed.owl	lung formation													biological_process											owl:Class	
GO:0102419	biolink:NamedThing	sn-2-glycerol-3-phosphate omega-OH-C22:0-CoA acyl transferase activity	Catalysis of the reaction: omega-hydroxy-C22:0-CoA + sn-glycerol 3-phosphate = coenzyme A + 2-omega-hydroxy-C22:0-LPA.	tmpzr1t_l9r_go_relaxed.owl					RHEA:33559|MetaCyc:RXN-13803|EC:2.3.1.198									molecular_function											owl:Class	
GO:0006708	biolink:NamedThing	ecdysone catabolic process	The chemical reactions and pathways resulting in the breakdown of ecdysone, (22R)-2-beta,3-beta,14,22,25-pentahydroxycholest-7-en-6-one, an ecdysteroid found in insects.	tmpzr1t_l9r_go_relaxed.owl	ecdysone breakdown|ecdysone degradation|ecdysone catabolism													biological_process											owl:Class	
GO:0033763	biolink:NamedThing	proline 3-hydroxylase activity	Catalysis of the reaction: L-proline + 2-oxoglutarate + O2 = cis-3-hydroxy-L-proline + succinate + CO2.	tmpzr1t_l9r_go_relaxed.owl	P-3-H|L-proline,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating) activity				EC:1.14.11.28|RHEA:20265|MetaCyc:1.14.11.28-RXN									molecular_function											owl:Class	
GO:0072101	biolink:NamedThing	specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway	A series of molecular signals generated as a consequence of any member of the BMP (bone morphogenetic protein) family binding to a cell surface receptor that results in the establishment of the ureteric bud such that there is a similar arrangement in form and relationship of parts along its anterior/posterior axis.	tmpzr1t_l9r_go_relaxed.owl	specification of ureteric bud anterior/posterior symmetry by BMP signalling pathway|specification of ureteric bud anterior/posterior asymmetry by BMP signaling pathway							mah	2010-02-10T02:21:03Z					biological_process											owl:Class	
GO:1902792	biolink:NamedThing	pyrroline-5-carboxylate reductase complex	A protein complex which is capable of pyrroline-5-carboxylate reductase activity.	tmpzr1t_l9r_go_relaxed.owl						An example of this is PYCR1 in human (P32322) in PMID:2722838 (inferred from direct assay).		bhm	2014-03-24T09:55:22Z					cellular_component											owl:Class	
GO:0071742	biolink:NamedThing	IgE immunoglobulin complex	A protein complex composed of two identical immunoglobulin heavy chains of the IgE isotype and two identical immunoglobulin light chains, held together by disulfide bonds. An IgE immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.	tmpzr1t_l9r_go_relaxed.owl						Note that an IgE immunoglobulin complex has the function of antigen binding if a suitable antigen is available.		mah	2010-03-24T01:44:53Z					cellular_component											owl:Class	
GO:0097626	biolink:NamedThing	low-affinity L-arginine transmembrane transporter activity	Enables the transfer of L-arginine from one side of a membrane to the other. In low-affinity transport the transporter is able to bind the solute only if it is present at very high concentrations.	tmpzr1t_l9r_go_relaxed.owl	low affinity L-arginine transmembrane transporter activity							pr	2014-08-20T14:24:22Z					molecular_function											owl:Class	
GO:0050442	biolink:NamedThing	3-propylmalate synthase activity	Catalysis of the reaction: glyoxylate + H(2)O + pentanoyl-CoA = 3-propylmalate + CoA + H(+).	tmpzr1t_l9r_go_relaxed.owl	beta-n-propylmalate synthase activity|3-propylmalate glyoxylate-lyase (CoA-pentanoylating) activity|3-(n-propyl)-malate synthase activity|N-propylmalate synthase activity|pentanoyl-CoA:glyoxylate C-pentanoyltransferase (thioester-hydrolysing, 1-carboxybutyl-forming)				KEGG_REACTION:R03040|MetaCyc:3-PROPYLMALATE-SYNTHASE-RXN|EC:2.3.3.12|RHEA:14457									molecular_function											owl:Class	
GO:0098540	biolink:NamedThing	lumenal side of trans-Golgi network transport vesicle membrane	The side (leaflet) of the trans-Golgi network transport vesicle membrane that faces the lumen.	tmpzr1t_l9r_go_relaxed.owl	internal side of trans-Golgi network transport vesicle membrane							dos	2013-10-24T11:55:02Z					cellular_component											owl:Class	
GO:0031703	biolink:NamedThing	type 2 angiotensin receptor binding	Binding to a type 2 angiotensin receptor.	tmpzr1t_l9r_go_relaxed.owl	AT2 receptor binding|type 2 angiotensin receptor ligand													molecular_function											owl:Class	
GO:0031701	biolink:NamedThing	angiotensin receptor binding	Binding to an angiotensin receptor.	tmpzr1t_l9r_go_relaxed.owl	angiotensin receptor ligand													molecular_function											owl:Class	
GO:1902802	biolink:NamedThing	regulation of siRNA-dependent facultative heterochromatin assembly	Any process that modulates the frequency, rate or extent of siRNA-dependent facultative heterochromatin assembly.	tmpzr1t_l9r_go_relaxed.owl	regulation of heterochromatin domain formation|regulation of HOOD assembly|regulation of heterochromatin domain assembly|regulation of HOOD formation	https://github.com/geneontology/go-ontology/issues/22326						mah	2014-03-25T14:44:54Z					biological_process											owl:Class	
GO:0047151	biolink:NamedThing	methylenetetrahydrofolate-tRNA-(uracil-5-)-methyltransferase (FADH2-oxidizing) activity	Catalysis of the reaction: 5,10-methylenetetrahydrofolate + tRNA containing uridine at position 54 + FADH + H+ = tetrahydrofolate + tRNA containing ribothymidine at position 54 + FAD+.	tmpzr1t_l9r_go_relaxed.owl	methylenetetrahydrofolate-tRNA-(uracil-5-)-methyltransferase (FADH-oxidizing) activity|methylenetetrahydrofolate-transfer ribonucleate uracil 5-methyltransferase activity|5,10-methylenetetrahydrofolate:tRNA (uracil-5-)-methyltransferase activity|folate-dependent ribothymidyl synthase activity|5,10-methylenetetrahydrofolate:tRNA-UPsiC (uracil-5-)-methyl-transferase activity				KEGG_REACTION:R03704|EC:2.1.1.74|RHEA:16873|MetaCyc:2.1.1.74-RXN									molecular_function											owl:Class	
GO:0070396	biolink:NamedThing	lipoteichoic acid catabolic process	The chemical reactions and pathways resulting in the breakdown of lipoteichoic acid, which is a major component of the cell wall of gram-positive bacteria and typically consists of a chain of glycerol-phosphate repeating units linked to a glycolipid anchor.	tmpzr1t_l9r_go_relaxed.owl	lipoteichoic acid breakdown|lipoteichoic acid degradation|lipoteichoic acid catabolism													biological_process											owl:Class	
GO:0070394	biolink:NamedThing	lipoteichoic acid metabolic process	The chemical reactions and pathways involving lipoteichoic acid, which is a major component of the cell wall of gram-positive bacteria and typically consists of a chain of glycerol-phosphate repeating units linked to a glycolipid anchor.	tmpzr1t_l9r_go_relaxed.owl	LTA metabolic process|lipoteichoic acid metabolism													biological_process											owl:Class	
GO:0042498	biolink:NamedThing	diacyl lipopeptide binding	Binding to a lipopeptide containing a nonprotein moiety consisting of two acyl groups.	tmpzr1t_l9r_go_relaxed.owl	diacylated lipopeptide binding|bacterial diacyl lipopeptide binding|bacterial diacyl lipoprotein binding					Note that bacterial lipopeptides are derived from bacterial lipoproteins, but the two terms are sometimes used interchangeably in the literature.								molecular_function											owl:Class	
GO:0071723	biolink:NamedThing	lipopeptide binding	Binding to a lipopeptide, any of a group of organic compounds comprising two or more amino acids linked by peptide bonds and containing a nonprotein group consisting of a lipid or lipids.	tmpzr1t_l9r_go_relaxed.owl	bacterial lipopeptide binding|bacterial lipoprotein binding					Note that bacterial lipopeptides are derived from bacterial lipoproteins, but the two terms are sometimes used interchangeably in the literature.		mah	2010-03-17T02:13:21Z					molecular_function											owl:Class	
GO:0061630	biolink:NamedThing	ubiquitin protein ligase activity	Catalysis of the transfer of ubiquitin to a substrate protein via the reaction X-ubiquitin + S -> X + S-ubiquitin, where X is either an E2 or E3 enzyme, the X-ubiquitin linkage is a thioester bond, and the S-ubiquitin linkage is an amide bond: an isopeptide bond between the C-terminal glycine of ubiquitin and the epsilon-amino group of lysine residues in the substrate or, in the linear extension of ubiquitin chains, a peptide bond the between the C-terminal glycine and N-terminal methionine of ubiquitin residues.	tmpzr1t_l9r_go_relaxed.owl	ER-associated E3 ligase|ubiquitin ligase activity|E3 involved in endoplasmic reticulum-associated degradation|ubiquitin ligase activity involved in ER-associated degradation pathway|ubiquitin protein ligase activity involved in ER-associated degradation pathway|ubiquitin-protein ligase activity involved in positive regulation of mitotic metaphase/anaphase transition|APC-Cdc20 complex activity|APC-fizzy related complex activity|protein ubiquitination activity|ubiquitin protein ligase activity involved in chloroplast disassembly|ubiquitin protein ligase activity involved in ERAD pathway|E3				Reactome:R-HSA-8939706|Reactome:R-HSA-8953946|Reactome:R-HSA-4608852|Reactome:R-HSA-8939335|Reactome:R-HSA-6804879|Reactome:R-HSA-5635864|Reactome:R-HSA-934604|Reactome:R-HSA-5674022|Reactome:R-HSA-8948775|Reactome:R-HSA-1225956|Reactome:R-HSA-5246693|Reactome:R-HSA-6782943|Reactome:R-HSA-5632648|Reactome:R-HSA-4641159|Reactome:R-HSA-990526|Reactome:R-HSA-5610737|Reactome:R-HSA-8952382|Reactome:R-HSA-8851011|Reactome:R-HSA-6798373|Reactome:R-HSA-68946|Reactome:R-HSA-8956026|Reactome:R-HSA-936475|Reactome:R-HSA-6781867|Reactome:R-HSA-5654679|Reactome:R-HSA-8848829|Reactome:R-HSA-9604629|Reactome:R-HSA-5690827|Reactome:R-HSA-5654684|Reactome:R-HSA-69015|Reactome:R-HSA-3640861|Reactome:R-HSA-6804441|Reactome:R-HSA-5654677|Reactome:R-HSA-4641253|Reactome:R-HSA-6807106|Reactome:R-HSA-8942101|Reactome:R-HSA-1504190|Reactome:R-HSA-5635856|Reactome:R-HSA-936462|Reactome:R-HSA-8854041|Reactome:R-HSA-8866546|Reactome:R-HSA-6790487|Reactome:R-HSA-5684071|Reactome:R-HSA-8867288|Reactome:R-HSA-6804253|Reactome:R-HSA-8877003|Reactome:R-HSA-9011300|Reactome:R-HSA-8938773|Reactome:R-HSA-5658424|Reactome:R-HSA-9706356|Reactome:R-HSA-9009308|Reactome:R-HSA-8948832|Reactome:R-HSA-8943040|Reactome:R-HSA-8956684|Reactome:R-HSA-9009403|Reactome:R-HSA-3322429|Reactome:R-HSA-8854051|Reactome:R-HSA-8952419|Reactome:R-HSA-9706354|Reactome:R-HSA-8943080|Reactome:R-HSA-9008479|Reactome:R-HSA-9686920|Reactome:R-HSA-9008076|Reactome:R-HSA-8854628|Reactome:R-HSA-8943003|Reactome:R-HSA-5689111|Reactome:R-HSA-5654672|Reactome:R-HSA-9033485|Reactome:R-HSA-5682858|Reactome:R-HSA-4641129|Reactome:R-HSA-5687081|Reactome:R-HSA-8876258|Reactome:R-HSA-9021523|Reactome:R-HSA-8875431|Reactome:R-HSA-6804942|Reactome:R-HSA-9686969|Reactome:R-HSA-201445|Reactome:R-HSA-8875183|Reactome:R-HSA-4641246|Reactome:R-HSA-6785361|Reactome:R-HSA-6804724|Reactome:R-HSA-8938815|Reactome:R-HSA-6807134|Reactome:R-HSA-8866856	This enzyme catalyzes a transferase reaction.		dph	2014-05-18T09:11:21Z			GO:1904264|GO:0090622|GO:0090302|GO:1904822		molecular_function											owl:Class	
GO:0016262	biolink:NamedThing	protein N-acetylglucosaminyltransferase activity	Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + protein = UDP + 4-N-(N-acetyl-D-glucosaminyl)-protein.	tmpzr1t_l9r_go_relaxed.owl	UDP-N-acetylglucosamine-peptide N-acetylglucosaminyltransferase activity|uridine diphosphoacetylglucosamine-protein acetylglucosaminyltransferase activity|uridine diphospho-N-acetylglucosamine:polypeptide beta-N-acetylglucosaminyltransferase activity|N-GlcNAc transferase activity|UDP-N-acetyl-D-glucosamine:protein beta-N-acetyl-D-glucosaminyl-transferase activity				RHEA:16533|EC:2.4.1.94|MetaCyc:2.4.1.94-RXN							GO:0016253		molecular_function											owl:Class	
GO:0047060	biolink:NamedThing	(R)-pantolactone dehydrogenase (flavin) activity	Catalysis of the reaction: (R)-pantolactone + A = 2-dehydropantolactone + AH(2).	tmpzr1t_l9r_go_relaxed.owl	2-dehydropantolactone reductase (flavin) activity|(R)-pantolactone:acceptor oxidoreductase (flavin-containing)|2-dehydropantoyl-lactone reductase (flavin) activity|(R)-pantoyllactone dehydrogenase (flavin) activity				MetaCyc:1.1.99.27-RXN|RHEA:21004|KEGG_REACTION:R03156|EC:1.1.99.27									molecular_function											owl:Class	
GO:0102937	biolink:NamedThing	16-alpha-hydroxygypsogenate-UDP-glucosyltransferase activity	Catalysis of the reaction: UDP-alpha-D-glucose + 16-alpha-hydroxygypsogenate = 16-alpha-hydroxygypsogenate-28-beta-D-glucoside + UDP.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-9014									molecular_function											owl:Class	
GO:0106185	biolink:NamedThing	histone H3-K37 methylation	The modification of histone H3 by addition of one or more methyl groups to lysine at position 37 of the histone.	tmpzr1t_l9r_go_relaxed.owl	histone H3K37me|histone lysine H3 K37 methylation|histone H3 K37 methylation							hjd	2019-04-24T14:36:23Z					biological_process											owl:Class	
GO:0050691	biolink:NamedThing	regulation of defense response to virus by host	Any host process that modulates the frequency, rate, or extent of the antiviral response of a host cell or organism.	tmpzr1t_l9r_go_relaxed.owl	host regulation of antiviral response|regulation by host of antiviral response|regulation of antiviral response by host													biological_process											owl:Class	
GO:0050688	biolink:NamedThing	regulation of defense response to virus	Any process that modulates the frequency, rate or extent of the antiviral response of a cell or organism.	tmpzr1t_l9r_go_relaxed.owl	regulation of antiviral response													biological_process											owl:Class	
GO:0140123	biolink:NamedThing	negative regulation of Lewy body formation	Any process that stops, prevents or reduces the frequency, rate or extent of Lewy body formation.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/14160						pg	2017-10-25T07:08:56Z					biological_process											owl:Class	
GO:0005826	biolink:NamedThing	actomyosin contractile ring	A cytoskeletal structure composed of actin filaments and myosin that forms beneath the plasma membrane of many cells, including animal cells and yeast cells, in a plane perpendicular to the axis of the spindle, i.e. the cell division plane.  In animal cells, the contractile ring is located at the cleavage furrow. In budding fungal cells, e.g. mitotic S. cerevisiae cells, the contractile ring forms at the mother-bud neck before mitosis.	tmpzr1t_l9r_go_relaxed.owl	constriction ring|CAR|actomyosin ring|cytokinetic ring|contractile actomyosin ring											GO:0030480		cellular_component											owl:Class	
GO:0070938	biolink:NamedThing	contractile ring	A cytoskeletal structure composed of filamentous protein that forms beneath the membrane of many cells or organelles, in the plane of cell or organelle division. Ring contraction is associated with centripetal growth of the membrane that divides the cytoplasm of the two daughter cells or organelles.	tmpzr1t_l9r_go_relaxed.owl	cytokinetic ring|constriction ring							mah	2009-09-22T02:41:32Z					cellular_component											owl:Class	
GO:0110091	biolink:NamedThing	negative regulation of hippocampal neuron apoptotic process	Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process in hippocampal neurons.	tmpzr1t_l9r_go_relaxed.owl								kmv	2018-02-13T21:25:01Z					biological_process											owl:Class	
GO:0001530	biolink:NamedThing	lipopolysaccharide binding	Binding to a lipopolysaccharide.	tmpzr1t_l9r_go_relaxed.owl	LPS binding|endotoxin binding													molecular_function											owl:Class	
GO:1902570	biolink:NamedThing	protein localization to nucleolus	A process in which a protein is transported to, or maintained in, a location within a nucleolus.	tmpzr1t_l9r_go_relaxed.owl	protein localisation in nucleolus|protein localisation to nucleolus|protein localization in nucleolus							mah	2013-12-10T16:25:28Z					biological_process											owl:Class	
GO:0010777	biolink:NamedThing	meiotic mismatch repair involved in reciprocal meiotic recombination	A system for the identification and correction of base-base mismatches, small insertion-deletion loops, and regions of heterology that are present in duplex DNA formed with strands from two recombining molecules resulting in meiotic recombination. Meiotic recombination is the cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1990081	biolink:NamedThing	trimethylamine receptor activity	Combining with the biogenic amine trimethylamine to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl								sp	2013-04-30T10:57:07Z					molecular_function											owl:Class	
GO:0032680	biolink:NamedThing	regulation of tumor necrosis factor production	Any process that modulates the frequency, rate or extent of tumor necrosis factor production.	tmpzr1t_l9r_go_relaxed.owl	regulation of tumor necrosis factor biosynthetic process|regulation of cachectin production|regulation of TNF-alpha production|regulation of TNF production|regulation of tumor necrosis factor secretion|regulation of tumor necrosis factor-alpha production					Note that this term refers only to the specific, original 'tumor necrosis factor' protein (TNF) and not other members of the tumor necrosis factor superfamily (those with the gene symbol root 'TNFSF').		sl	2015-07-09T19:50:02Z			GO:0042534|GO:1904467		biological_process											owl:Class	
GO:0140429	biolink:NamedThing	positive regulation of mitotic sister chromatid biorientation	Any process that activates or increases the frequency, rate or extent of mitotic sister chromatid biorientation, the mitotic cell cycle process in which sister chromatids establish stable, end-on attachments to the plus ends of microtubules emanating from opposite spindle poles, oriented such that separation can proceed.	tmpzr1t_l9r_go_relaxed.owl	repair of mitotic merotelic kinetochore attachment defects|repair of mitotic merotelic kinetochore attachment defect|repair of mitotic mono-orientation defect|correction of mono-orientation defects|repair of mitotic mono-orientation defects|correction of merotelic kinetochore attachment, mitotic|correction of syntelic kinetochore attachment, mitotic	https://github.com/geneontology/go-ontology/issues/18815						jl	2015-01-05T16:54:39Z			GO:0098783|GO:1990598		biological_process											owl:Class	
GO:0140273	biolink:NamedThing	repair of mitotic kinetochore microtubule attachment defect	The mitotic cell cycle process where kinetochore microtubule attachment defects are corrected.	tmpzr1t_l9r_go_relaxed.owl	correction of mitotic kinetochore microtubule attachment defects|repair of mitotic kinetochore microtubule attachment defects							pg	2018-10-01T11:29:24Z					biological_process											owl:Class	
GO:0046460	biolink:NamedThing	neutral lipid biosynthetic process	The chemical reactions and pathways resulting in the formation of neutral lipids, lipids only soluble in solvents of very low polarity.	tmpzr1t_l9r_go_relaxed.owl	neutral lipid biosynthesis|neutral lipid formation|neutral lipid anabolism|neutral lipid synthesis													biological_process											owl:Class	
GO:0052658	biolink:NamedThing	inositol-1,4,5-trisphosphate 5-phosphatase activity	Catalysis of the reaction: 1D-myo-inositol 1,4,5-trisphosphate + H2O = 1D-myo-inositol 1,4-bisphosphate + phosphate.	tmpzr1t_l9r_go_relaxed.owl	1D-myo-inositol-1,4,5-trisphosphate 5-phosphohydrolase activity|myo-inositol-1,4,5-trisphosphate 5-phosphatase activity|inositol phosphate 5-phosphomonoesterase activity|inositol 1,4,5-trisphosphate phosphatase activity|InsP3 5-phosphatase activity|D-myo-inositol(1,4,5)-trisphosphate 5-phosphatase activity|type II inositol polyphosphate 5-phosphatase activity|5PTase activity|L-myo-inositol 1,4,5-trisphosphate-monoesterase activity|InsP(3) 5-phosphatase activity|inositol trisphosphate phosphomonoesterase activity|inositol triphosphate 5-phosphomonoesterase activity|inosine triphosphatase activity|D-myo-inositol 1,4,5-triphosphate 5-phosphatase activity|Ins(1,4,5)P3 5-phosphatase activity|D-myo-inositol 1,4,5-trisphosphate 5-phosphatase activity|type I inositol-polyphosphate phosphatase activity|inositol polyphosphate-5-phosphatase activity				KEGG_REACTION:R03394|Reactome:R-HSA-1855174|Reactome:R-HSA-1855222|EC:3.1.3.56|MetaCyc:3.1.3.56-RXN|RHEA:19797									molecular_function											owl:Class	
GO:1905631	biolink:NamedThing	cellular response to glyceraldehyde	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glyceraldehyde stimulus.	tmpzr1t_l9r_go_relaxed.owl								sl	2016-10-31T16:32:27Z					biological_process											owl:Class	
GO:1905630	biolink:NamedThing	response to glyceraldehyde	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glyceraldehyde stimulus.	tmpzr1t_l9r_go_relaxed.owl								sl	2016-10-31T16:32:19Z					biological_process											owl:Class	
GO:2000222	biolink:NamedThing	positive regulation of pseudohyphal growth	Any process that activates or increases the frequency, rate or extent of pseudohyphal growth.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-11-03T04:37:03Z					biological_process											owl:Class	
GO:0102498	biolink:NamedThing	maltose glucosidase activity	Catalysis of the reaction: H2O + maltose = 2 glucose.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-15910									molecular_function											owl:Class	
GO:1901396	biolink:NamedThing	negative regulation of transforming growth factor beta2 activation	Any process that stops, prevents or reduces the frequency, rate or extent of transforming growth factor beta2 activation.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of TGF-beta 2 activation|inhibition of TGFbeta 2 activation|downregulation of TGF-beta 2 activation|inhibition of TGFB2 activation|down regulation of TGF-beta 2 activation|down-regulation of TGFB2 activation|inhibition of TGF-beta 2 activation|inhibition of transforming growth factor beta2 activation|down regulation of TGFbeta 2 activation|negative regulation of TGFB2 activation|down regulation of transforming growth factor beta2 activation|down regulation of TGFB2 activation|downregulation of transforming growth factor beta2 activation|downregulation of TGFbeta 2 activation|down-regulation of TGF-beta 2 activation|downregulation of TGFB2 activation|down-regulation of TGFbeta 2 activation|down-regulation of transforming growth factor beta2 activation|negative regulation of TGFbeta 2 activation							bf	2012-10-01T10:47:59Z					biological_process											owl:Class	
GO:0030413	biolink:NamedThing	competence pheromone activity	A small peptide excreted by a naturally transformable bacterium (e.g. Bacillus subtilis) that transmits a signal required for the establishment of competence.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0005186	biolink:NamedThing	pheromone activity	The activity of binding to and activating specific cell surface receptors, thereby inducing behavioral, developmental, or physiological response(s) from a responding organism or cell. The substance may be released or retained on the cell surface. Pheromones may serve as a specific attractant, social communicator, or sexual stimulant.	tmpzr1t_l9r_go_relaxed.owl						Also consider annotating to 'receptor agonist activity ; GO:0048018'.								molecular_function											owl:Class	
GO:0033340	biolink:NamedThing	pelvic fin development	The process whose specific outcome is the progression of the pelvic fin over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0060173	biolink:NamedThing	limb development	The process whose specific outcome is the progression of a limb over time, from its formation to the mature structure. A limb is an appendage of an animal used for locomotion or grasping. Examples include legs, arms or some types of fin.	tmpzr1t_l9r_go_relaxed.owl	paired limb/fin development|limb bud development				Wikipedia:Limb_development									biological_process											owl:Class	
GO:0036362	biolink:NamedThing	ascus membrane	A double layer of lipid molecules that surrounds an ascus, a capsule containing the sexual spores in some fungi.	tmpzr1t_l9r_go_relaxed.owl								bf	2012-09-21T11:21:41Z					cellular_component											owl:Class	
GO:0034917	biolink:NamedThing	2-methylhex-2-enoyl-CoA hydratase activity	Catalysis of the reaction: 2-methylhex-2-enoyl-CoA + H2O = 3-hydroxy-2-methylhexanoyl-CoA.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0929									molecular_function											owl:Class	
GO:0097608	biolink:NamedThing	transverse flagellum	A motile cilium found in dinoflagellates. It coils around the cell and provides the forward thrust for motility. It is often contained in a furrow called the cingulum, and emerges from a flagellar pore located in the cingulum.	tmpzr1t_l9r_go_relaxed.owl	transverse cilium					Note that we deem cilium and microtubule-based flagellum to be equivalent. In this case community usage refers to 'flagellum' rather than 'cilium', hence the primary term name, but the cilium parentage is deliberate.		pr	2014-06-09T11:14:37Z					cellular_component											owl:Class	
GO:0060894	biolink:NamedThing	limb spinous cell fate specification	The process in which a cell becomes capable of differentiating autonomously into a limb spinous cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-08-13T01:46:23Z					biological_process											owl:Class	
GO:0009957	biolink:NamedThing	epidermal cell fate specification	The process in which a cell becomes capable of differentiating autonomously into an epidermal cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.	tmpzr1t_l9r_go_relaxed.owl	hypodermal cell fate specification											GO:0043356		biological_process											owl:Class	
GO:0070559	biolink:NamedThing	lysosomal multienzyme complex	A protein complex found in the lysosome that contains beta-galactosidase, cathepsin A, alpha-neuraminidase and N-acetylgalactosamine-6-sulfate sulfatase, and is involved in glycosaminoglycan catabolism.	tmpzr1t_l9r_go_relaxed.owl	GALNS-lysosomal hydrolase 1.27 MDa complex													cellular_component											owl:Class	
GO:0014894	biolink:NamedThing	response to denervation involved in regulation of muscle adaptation	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a denervation stimulus. This process occurs as part of the regulation of muscle adaptation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0090724	biolink:NamedThing	central region of growth cone	The center of the migrating motile tip of a growing nerve cell axon or dendrite.	tmpzr1t_l9r_go_relaxed.owl								tb	2016-11-18T12:44:25Z					cellular_component											owl:Class	
GO:0018890	biolink:NamedThing	cyanamide metabolic process	The chemical reactions and pathways involving cyanamide, NCNH2, a cyanide compound which has been used as a fertilizer, defoliant and in many manufacturing processes. It often occurs as the calcium salt, sometimes also referred to as cyanamide. The citrated calcium salt is used in the treatment of alcoholism.	tmpzr1t_l9r_go_relaxed.owl	cyanamide metabolism				UM-BBD_pathwayID:cnm									biological_process											owl:Class	
GO:0034791	biolink:NamedThing	isobutylamine N-hydroxylase activity	Catalysis of the reaction: isobutylamine + NADPH + O2 = isobutylhydroxylamine + NADP+ + H2O.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r1053|EC:1.14.13.-									molecular_function											owl:Class	
GO:2000819	biolink:NamedThing	regulation of nucleotide-excision repair	Any process that modulates the frequency, rate or extent of nucleotide-excision repair.	tmpzr1t_l9r_go_relaxed.owl	regulation of pyrimidine-dimer repair, DNA damage excision|regulation of intrastrand cross-link repair|regulation of NER|regulation of interstrand crosslink repair							pr	2011-07-13T08:55:39Z					biological_process											owl:Class	
GO:0071750	biolink:NamedThing	dimeric IgA immunoglobulin complex	A protein complex composed of two monomeric IgA immunoglobulin complexes linked through both direct disulfide bonds and through a disulfide binded monomer of J chain acting as a bridge. Each IgA monomer consists of two identical immunoglobulin heavy chains of an IgA isotype and two identical immunoglobulin light chains, held together by disulfide bonds. Dimeric IgA is sometimes complexed additionally with secretory component, and present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.	tmpzr1t_l9r_go_relaxed.owl	dimeric IgA antibody|dimeric IgA1 antibody					Note that an IgA immunoglobulin complex has the function of antigen binding if a suitable antigen is available. Dimeric IgA is by far the most common form of polymeric IgA. In human only the IgA1 isotype is capable of a dimeric form.		mah	2010-03-24T01:44:53Z					cellular_component											owl:Class	
GO:0001797	biolink:NamedThing	negative regulation of type IIa hypersensitivity	Any process that stops, prevents, or reduces the rate of type IIa hypersensitivity, a type of inflammatory response.	tmpzr1t_l9r_go_relaxed.owl	downregulation of type IIa hypersensitivity|down-regulation of type IIa hypersensitivity|inhibition of type IIa hypersensitivity|down regulation of type IIa hypersensitivity													biological_process											owl:Class	
GO:0032908	biolink:NamedThing	regulation of transforming growth factor beta1 production	Any process that modulates the frequency, rate, or extent of production of transforming growth factor-beta1.	tmpzr1t_l9r_go_relaxed.owl	regulation of TGFB1 production|regulation of transforming growth factor-beta1 production|regulation of TGF-B1 production													biological_process											owl:Class	
GO:1905411	biolink:NamedThing	positive regulation of mitotic cohesin unloading	Any process that activates or increases the frequency, rate or extent of mitotic cohesin unloading.	tmpzr1t_l9r_go_relaxed.owl								vw	2016-08-25T15:45:30Z					biological_process											owl:Class	
GO:1905779	biolink:NamedThing	positive regulation of exonuclease activity	Any process that activates or increases the frequency, rate or extent of exonuclease activity.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of exonuclease activity|up regulation of exonuclease IX activity|positive regulation of exonuclease IX activity|up-regulation of exonuclease IX activity|activation of exonuclease IX activity|up regulation of exonuclease activity|activation of exonuclease activity|upregulation of exonuclease activity|upregulation of exonuclease IX activity							nc	2016-12-21T21:32:24Z					biological_process											owl:Class	
GO:0005004	biolink:NamedThing	GPI-linked ephrin receptor activity	Combining with a GPI-anchored ephrin to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	GPI-linked Eph receptor activity													molecular_function											owl:Class	
GO:0045692	biolink:NamedThing	negative regulation of embryo sac central cell differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of embryo sac central cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of female gametophyte central cell differentiation|down-regulation of female gametophyte central cell differentiation|inhibition of female gametophyte central cell differentiation|downregulation of female gametophyte central cell differentiation|down regulation of female gametophyte central cell differentiation													biological_process											owl:Class	
GO:0045691	biolink:NamedThing	regulation of embryo sac central cell differentiation	Any process that modulates the frequency, rate or extent of female gametophyte central cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	regulation of female gametophyte central cell differentiation													biological_process											owl:Class	
GO:1903100	biolink:NamedThing	1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate metabolic process	The chemical reactions and pathways involving 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate.	tmpzr1t_l9r_go_relaxed.owl	1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate metabolism							bhm	2014-06-04T14:14:24Z					biological_process											owl:Class	
GO:1901235	biolink:NamedThing	(R)-carnitine transmembrane transporter activity	Enables the transfer of (R)-carnitine from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl					RHEA:34959			jl	2012-08-07T14:46:17Z					molecular_function											owl:Class	
GO:1900948	biolink:NamedThing	negative regulation of isoprene biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of isoprene biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	downregulation of 2-methyl-1,3-butadiene biosynthesis|down-regulation of 2-methyl-1,3-butadiene biosynthetic process|inhibition of hemiterpene biosynthetic process|inhibition of 2-methyl-1,3-butadiene biosynthesis|inhibition of 2-methyl-1,3-butadiene biosynthetic process|down regulation of hemiterpene biosynthetic process|down regulation of 2-methyl-1,3-butadiene biosynthetic process|negative regulation of hemiterpene biosynthetic process|negative regulation of 2-methyl-1,3-butadiene biosynthetic process|negative regulation of 2-methyl-1,3-butadiene biosynthesis|downregulation of hemiterpene biosynthesis|inhibition of hemiterpene biosynthesis|down regulation of hemiterpene biosynthesis|downregulation of isoprene biosynthetic process|negative regulation of hemiterpene biosynthesis|down regulation of 2-methyl-1,3-butadiene biosynthesis|downregulation of 2-methyl-1,3-butadiene biosynthetic process|down-regulation of 2-methyl-1,3-butadiene biosynthesis|down-regulation of hemiterpene biosynthetic process|downregulation of hemiterpene biosynthetic process|down-regulation of hemiterpene biosynthesis|down-regulation of isoprene biosynthetic process|inhibition of isoprene biosynthetic process|down regulation of isoprene biosynthetic process							tt	2012-06-14T03:21:47Z					biological_process											owl:Class	
GO:0003408	biolink:NamedThing	optic cup formation involved in camera-type eye development	The developmental process pertaining to the initial formation of the optic cup, a two-walled vesicle formed from the optic vesicle.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-12-21T02:37:12Z					biological_process											owl:Class	
GO:0032419	biolink:NamedThing	extrinsic component of lysosome membrane	The component of an lysosome membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.	tmpzr1t_l9r_go_relaxed.owl	extrinsic to lysosome membrane|extrinsic to lysosomal membrane													cellular_component											owl:Class	
GO:0000306	biolink:NamedThing	extrinsic component of vacuolar membrane	The component of a vacuolar membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.	tmpzr1t_l9r_go_relaxed.owl	extrinsic to vacuolar membrane													cellular_component											owl:Class	
GO:1900370	biolink:NamedThing	positive regulation of RNA interference	Any process that activates or increases the frequency, rate or extent of RNA interference.	tmpzr1t_l9r_go_relaxed.owl	activation of posttranscriptional gene silencing by siRNA|upregulation of RNAi|upregulation of RNA interference|up-regulation of RNA interference|up regulation of RNA interference|up-regulation of RNAi|positive regulation of RNAi|activation of RNAi|positive regulation of posttranscriptional gene silencing by siRNA|upregulation of posttranscriptional gene silencing by siRNA|up regulation of posttranscriptional gene silencing by siRNA|activation of RNA interference|up regulation of RNAi|up-regulation of posttranscriptional gene silencing by siRNA							kmv	2012-04-13T08:29:00Z					biological_process											owl:Class	
GO:1903655	biolink:NamedThing	phosphorylation of RNA polymerase II C-terminal domain serine 2 residues involved in positive regulation of transcription elongation from RNA polymerase II promoter	Any phosphorylation of RNA polymerase II C-terminal domain serine 2 residues that is involved in positive regulation of transcription elongation from RNA polymerase II promoter.	tmpzr1t_l9r_go_relaxed.owl								vw	2014-11-25T11:04:16Z					biological_process											owl:Class	
GO:1905762	biolink:NamedThing	CCR4-NOT complex binding	Binding to a CCR4-NOT complex.	tmpzr1t_l9r_go_relaxed.owl								mah	2016-12-15T15:48:53Z					molecular_function											owl:Class	
GO:0050260	biolink:NamedThing	ribose-5-phosphate-ammonia ligase activity	Catalysis of the reaction: D-ribose 5-phosphate + ATP + NH(4)(+) = 5-phospho-D-ribosylamine + ADP + 2 H(+) + phosphate.	tmpzr1t_l9r_go_relaxed.owl	ammonia-ribose 5-phosphate aminotransferase activity|ribose-5-phosphate:ammonia ligase (ADP-forming)|5-phosphoribosylamine synthetase activity|ribose 5-phosphate aminotransferase activity				EC:6.3.4.7|MetaCyc:RIBOSE-5-PHOSPHATE--AMMONIA-LIGASE-RXN|KEGG_REACTION:R01053|RHEA:13777									molecular_function											owl:Class	
GO:0050990	biolink:NamedThing	N-terminal protein amino acid carbamoylation	The carbamoylation of the N-terminal amino acid of proteins.	tmpzr1t_l9r_go_relaxed.owl	N-terminal protein amino acid carbamylation													biological_process											owl:Class	
GO:0046469	biolink:NamedThing	platelet activating factor metabolic process	The chemical reactions and pathways involving platelet activating factor, 1-O-alkyl-2-acetyl-sn-glycerol 3-phosphocholine, where alkyl = hexadecyl or octadecyl. Platelet activating factor is an inflammatory mediator released from a variety of cells in response to various stimuli.	tmpzr1t_l9r_go_relaxed.owl	PAF metabolism|PAF metabolic process|platelet activating factor metabolism													biological_process											owl:Class	
GO:1902483	biolink:NamedThing	cytotoxic T cell pyroptotic process	Any pyroptotic process in a cytotoxic T cell.	tmpzr1t_l9r_go_relaxed.owl	cytotoxic T-cell apoptotic process|cytotoxic T cell apoptosis|cytotoxic T-lymphocyte apoptosis|cytotoxic T lymphocyte apoptotic process|cytotoxic T-lymphocyte apoptotic process|cytotoxic T-cell apoptosis|cytotoxic T cell apoptotic process|cytotoxic T lymphocyte apoptosis							nhn	2013-11-04T17:23:48Z					biological_process											owl:Class	
GO:0070269	biolink:NamedThing	pyroptosis	A caspase-1-dependent cell death subroutine that is associated with the generation of pyrogenic mediators such as IL-1beta and IL-18.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0048781	biolink:NamedThing	regulation of cyanophore differentiation	Any process that modulates the frequency, rate or extent of cyanophore differentiation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0120110	biolink:NamedThing	interphase mitotic telomere clustering	The process whereby the mitotic telomeres are gathered together during, or prior to, attachment to the nuclear envelope.	tmpzr1t_l9r_go_relaxed.owl	mitotic telomere clustering during interphase					It is likely that both intra chromosome telomere clustering and inter-chromosome occur because a single focus is sometimes observed, although this has yet to be proven.		krc	2017-11-01T18:09:08Z					biological_process											owl:Class	
GO:0002148	biolink:NamedThing	hypochlorous acid metabolic process	The chemical reactions and pathways involving hypochlorous acid.	tmpzr1t_l9r_go_relaxed.owl	HOCl metabolic process|HClO metabolic process|hypochlorite metabolic process|hypochlorous acid metabolism							hjd	2009-10-13T10:27:48Z					biological_process											owl:Class	
GO:0045571	biolink:NamedThing	negative regulation of imaginal disc growth	Any process that stops, prevents, or reduces the frequency, rate or extent of imaginal disc growth.	tmpzr1t_l9r_go_relaxed.owl	downregulation of imaginal disc growth|down-regulation of imaginal disc growth|down regulation of imaginal disc growth|inhibition of imaginal disc growth													biological_process											owl:Class	
GO:0030200	biolink:NamedThing	heparan sulfate proteoglycan catabolic process	The chemical reactions and pathways resulting in the breakdown of proteoglycan containing heparan sulfate, any member of a group of glycosaminoglycans that have repeat units consisting of alternating alpha-(1->4) linked hexuronic acid and glucosamine residues, the former being a mixture of sulfated and nonsulfated D-glucuronic and L-iduronic acids, and the latter being either sulfated or acetylated on its amino group as well as sulfated on one of its hydroxyl groups.	tmpzr1t_l9r_go_relaxed.owl	heparin proteoglycan catabolic process|heparan sulfate proteoglycan degradation|heparan sulphate proteoglycan catabolic process|heparan sulphate proteoglycan catabolism|heparan sulfate proteoglycan breakdown|heparan sulfate proteoglycan catabolism													biological_process											owl:Class	
GO:0008830	biolink:NamedThing	dTDP-4-dehydrorhamnose 3,5-epimerase activity	Catalysis of the reaction: dTDP-4-dehydro-6-deoxy-alpha-D-glucose = dTDP-4-dehydro-6-deoxy-L-mannose.	tmpzr1t_l9r_go_relaxed.owl	TDP-4-ketorhamnose 3,5-epimerase activity|TDP-4-keto-L-rhamnose-3,5-epimerase activity|dTDP-4-dehydro-6-deoxy-D-glucose 3,5-epimerase activity|dTDP-4-keto-6-deoxyglucose 3,5-epimerase activity|thymidine diphospho-4-ketorhamnose 3,5-epimerase activity				MetaCyc:DTDPDEHYDRHAMEPIM-RXN|RHEA:16969|EC:5.1.3.13|KEGG_REACTION:R06514									molecular_function											owl:Class	
GO:0001969	biolink:NamedThing	regulation of activation of membrane attack complex	Any process that modulates the frequency, rate or extent of the activation of the membrane attack complex components of the complement cascade.	tmpzr1t_l9r_go_relaxed.owl	regulation of activation of the terminal complement cascade|regulation of MAC formation|regulation of membrane attack complex assembly|regulation of activation of MAC|regulation of MAC assembly|regulation of membrane attack complex formation|regulation of activation of terminal complement complex|regulation of activation of TCC													biological_process											owl:Class	
GO:0102689	biolink:NamedThing	UDP-glucose:isopentenyladenine 7-N-glucosyltransferase activity	Catalysis of the reaction: UDP-alpha-D-glucose + N(6)-dimethylallyladenine <=> H+ + 7-(alpha-D-glucosyl)-N(6)-isopentenyladenine + UDP.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-4727									molecular_function											owl:Class	
GO:0102825	biolink:NamedThing	quercetin 3-O-rhamnoside-glucosyltransferase activity	Catalysis of the reaction: UDP-alpha-D-glucose(2-) + quercetin 3-O-rhamnoside <=> quercetin 3-O-rhamnoside-7-O-glucoside + UDP.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-8268									molecular_function											owl:Class	
GO:0045252	biolink:NamedThing	oxoglutarate dehydrogenase complex	A complex of multiple copies of three enzymatic components: oxoglutarate dehydrogenase (lipoamide) ; EC:1.2.4.2 (E1), dihydrolipoamide S-succinyltransferase ; EC:2.3.1.61 (E2) and dihydrolipoamide dehydrogenase ; EC:1.8.1.4 (E3); catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and carbon dioxide (CO2).	tmpzr1t_l9r_go_relaxed.owl	dihydrolipoamide S-succinyltransferase complex					See also the molecular functions term 'oxoglutarate dehydrogenase (succinyl-transferring) activity ; GO:0004591', 'dihydrolipoyllysine-residue succinyltransferase activity ; GO:0004149' and 'dihydrolipoyl dehydrogenase activity ; GO:0004148'.								cellular_component											owl:Class	
GO:2000428	biolink:NamedThing	regulation of neutrophil aggregation	Any process that modulates the frequency, rate or extent of neutrophil aggregation.	tmpzr1t_l9r_go_relaxed.owl	regulation of neutrocyte aggregation|regulation of neutrophil leucocyte aggregation|regulation of neutrophilic leukocyte aggregation							ebc	2011-02-28T05:18:54Z					biological_process											owl:Class	
GO:0018923	biolink:NamedThing	limonene metabolic process	The chemical reactions and pathways involving limonene (4-isopropenyl-1-methyl-cyclohexene), a monocyclic monoterpene.	tmpzr1t_l9r_go_relaxed.owl	limonene metabolism				UM-BBD_pathwayID:lim									biological_process											owl:Class	
GO:0018322	biolink:NamedThing	protein tyrosinylation	The addition of a tyrosine molecule to a protein amino acid.	tmpzr1t_l9r_go_relaxed.owl	protein amino acid tyrosinylation													biological_process											owl:Class	
GO:0090454	biolink:NamedThing	glutamate transmembrane import into vacuole	The directed movement of glutamate into the vacuole across the vacuolar membrane.	tmpzr1t_l9r_go_relaxed.owl	vacuolar glutamate import							tb	2012-09-24T14:12:46Z					biological_process											owl:Class	
GO:0061766	biolink:NamedThing	positive regulation of lung blood pressure	The process that increases the force with which blood travels through the lungs.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of pulmonary blood pressure							dph	2016-04-27T11:54:34Z					biological_process											owl:Class	
GO:0120094	biolink:NamedThing	negative regulation of peptidyl-lysine crotonylation	Any process that stops or reduces the rate of crotonylation of a lysine residue in a protein.	tmpzr1t_l9r_go_relaxed.owl								krc	2017-08-22T20:36:36Z					biological_process											owl:Class	
GO:0043653	biolink:NamedThing	mitochondrial fragmentation involved in apoptotic process	The change in the morphology of the mitochondria in an apoptotic cell from a highly branched network to a fragmented vesicular form.	tmpzr1t_l9r_go_relaxed.owl	mitochondrial fission during apoptosis|mitochondrial fragmentation involved in apoptosis					Although most of the processes described under 'apoptotic mitochondrial changes' take place during the signaling phase of apoptosis, 'mitochondrial fragmentation involved in apoptotic process' cannot be confidently placed there. It is still controversial whether this process is involved in the signaling phase of apoptosis or not, so it was placed under the more generic 'apoptotic mitochondrial changes' parent rather than linked to the signaling or the execution phase until further research clarifies the matter.								biological_process											owl:Class	
GO:0008637	biolink:NamedThing	apoptotic mitochondrial changes	The morphological and physiological alterations undergone by mitochondria during apoptosis.	tmpzr1t_l9r_go_relaxed.owl						This term was created to reflect the fundamental role of the mitochondrial compartment in apoptosis. Most processes under this node occur during the signaling phase of apoptosis, but e.g. GO:0043653 'mitochondrial fragmentation involved in apoptotic process' cannot be confidently placed under the signaling phase. For this reason, the parent term GO:0008637 'apoptotic mitochondrial changes' is not linked to the signaling or execution phase specifically, but its descendants are when current knowledge allows for it.								biological_process											owl:Class	
GO:1903691	biolink:NamedThing	positive regulation of wound healing, spreading of epidermal cells	Any process that activates or increases the frequency, rate or extent of wound healing, spreading of epidermal cells.	tmpzr1t_l9r_go_relaxed.owl	activation of wound healing, spreading of epidermal cells|up regulation of wound healing, spreading of epidermal cells|up-regulation of wound healing, spreading of epidermal cells|upregulation of wound healing, spreading of epidermal cells							als	2014-12-01T15:54:35Z					biological_process											owl:Class	
GO:1903467	biolink:NamedThing	negative regulation of mitotic DNA replication initiation	Any process that stops, prevents or reduces the frequency, rate or extent of DNA replication initiation involved in mitotic DNA replication.	tmpzr1t_l9r_go_relaxed.owl	down regulation of DNA replication initiation involved in mitotic DNA replication|downregulation of DNA replication initiation involved in mitotic cell cycle DNA replication|inhibition of DNA replication initiation involved in mitotic DNA replication|downregulation of DNA replication initiation involved in mitotic DNA replication|down regulation of DNA replication initiation involved in mitotic cell cycle DNA replication|negative regulation of DNA replication initiation involved in mitotic cell cycle DNA replication|down-regulation of DNA replication initiation involved in mitotic cell cycle DNA replication|inhibition of DNA replication initiation involved in mitotic cell cycle DNA replication|down-regulation of DNA replication initiation involved in mitotic DNA replication							vw	2014-09-23T13:38:58Z					biological_process											owl:Class	
GO:0010023	biolink:NamedThing	proanthocyanidin biosynthetic process	The chemical reactions and pathways resulting in the formation of proanthocyanidin.	tmpzr1t_l9r_go_relaxed.owl	proanthocyanidin formation|proanthocyanidin biosynthesis|proanthocyanidin anabolism|proanthocyanidin synthesis				MetaCyc:PWY-641									biological_process											owl:Class	
GO:0008832	biolink:NamedThing	dGTPase activity	Catalysis of the reaction: dGTP + H(2)O = 2'-deoxyguanosine + 2 H(+) + triphosphate.	tmpzr1t_l9r_go_relaxed.owl	deoxyguanosine triphosphatase activity|deoxyguanosine triphosphate triphosphohydrolase activity|deoxyguanosinetriphosphate triphosphohydrolase activity|deoxy-GTPase activity|dGTP triphosphohydrolase activity|deoxyguanosine 5-triphosphate triphosphohydrolase activity				EC:3.1.5.1|KEGG_REACTION:R01856|MetaCyc:DGTPTRIPHYDRO-RXN|RHEA:15193									molecular_function											owl:Class	
GO:0016793	biolink:NamedThing	triphosphoric monoester hydrolase activity	Catalysis of the hydrolysis of a triphosphoester to give a triphosphate group and a free hydroxyl group.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-8866601|EC:3.1.5.-									molecular_function											owl:Class	
GO:0060338	biolink:NamedThing	regulation of type I interferon-mediated signaling pathway	Any process that modulates the rate, frequency or extent of a type I interferon-mediated signaling pathway. A type I interferon-mediated signaling pathway is the series of molecular events generated as a consequence of a type I interferon binding to a cell surface receptor.	tmpzr1t_l9r_go_relaxed.owl	regulation of type I interferon-mediated signalling pathway													biological_process											owl:Class	
GO:0007442	biolink:NamedThing	hindgut morphogenesis	The process in which the anatomical structures of the hindgut are generated and organized.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0009745	biolink:NamedThing	sucrose mediated signaling	A series of molecular signals mediated by the detection of sucrose.	tmpzr1t_l9r_go_relaxed.owl	sucrose mediated signalling													biological_process											owl:Class	
GO:0060510	biolink:NamedThing	type II pneumocyte differentiation	The process in which a relatively unspecialized cell acquires specialized features of a type II pneumocyte. A type II pneumocyte is a surfactant secreting cell that contains abundant cytoplasm containing numerous lipid-rich multilamellar bodies.	tmpzr1t_l9r_go_relaxed.owl	granular pneumocyte differentiation|large alveolar cell differentiation|great alveolar cell differentiation													biological_process											owl:Class	
GO:0061140	biolink:NamedThing	lung secretory cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a lung secretory cell. A lung secretory cell is a specialized epithelial cell of the lung that contains large secretory granules in its apical part.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-05-25T09:28:53Z					biological_process											owl:Class	
GO:0102047	biolink:NamedThing	indole-3-acetyl-glycine synthetase activity	Catalysis of the reaction: indole-3-acetate + glycine + ATP(4-) <=> H+ + indole-3-acetyl-glycine + AMP(2-) + diphosphoric acid.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-10429									molecular_function											owl:Class	
GO:1901530	biolink:NamedThing	response to hypochlorite	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hypochlorite stimulus.	tmpzr1t_l9r_go_relaxed.owl								pr	2012-10-24T07:12:21Z					biological_process											owl:Class	
GO:0043078	biolink:NamedThing	polar nucleus	Either of two nuclei located centrally in a flowering plant embryo sac that eventually fuse to form the endosperm nucleus.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0098830	biolink:NamedThing	presynaptic endosome	An endosome present in the presynapse that fuses with endocytic vesicles arising in the presynaptic endocytic zone.  This organelle is believed to be involved in regeneration of synaptic vesicles.	tmpzr1t_l9r_go_relaxed.owl						As of 2015, there is still controversy over the nature of presynaptic endosomes and their relationship to regular endosomes.  See Jahne et al., 2015 (PMID:25939282) for details.								cellular_component											owl:Class	
GO:0006420	biolink:NamedThing	arginyl-tRNA aminoacylation	The process of coupling arginine to arginyl-tRNA, catalyzed by arginyl-tRNA synthetase. The arginyl-tRNA synthetase is a  class-I synthetase. The activated amino acid is transferred to the 2'-OH group of an alanine accetping tRNA.  The  2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0071726	biolink:NamedThing	cellular response to diacyl bacterial lipopeptide	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diacylated bacterial lipopeptide stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to diacylated bacterial lipoprotein					Note that bacterial lipopeptides are derived from bacterial lipoproteins, but the two terms are sometimes used interchangeably in the literature.		mah	2010-03-17T02:17:02Z					biological_process											owl:Class	
GO:0102600	biolink:NamedThing	cytochrome P450 dependent 12,13beta-epoxy-beta-amyrin hydroxylase activity	Catalysis of the reaction: 12,13beta-epoxy-beta-amyrin + O2 + H+ + NAD(P)H <=> 12,13beta-epoxy-16beta-hydroxy-beta-amyrin + H2O + NAD(P).	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-15384									molecular_function											owl:Class	
GO:1903837	biolink:NamedThing	regulation of mRNA 3'-UTR binding	Any process that modulates the frequency, rate or extent of mRNA 3'-UTR binding.	tmpzr1t_l9r_go_relaxed.owl	regulation of mRNA 3' UTR binding							als	2015-01-22T11:53:59Z					biological_process											owl:Class	
GO:1990429	biolink:NamedThing	peroxisomal importomer complex	A protein complex responsible for transporting proteins into the peroxisomal matrix. An example of this complex is Pex14 found in S. cerevisae which has 9 core components and 12 transient interaction partners.	tmpzr1t_l9r_go_relaxed.owl	peroxisomal import pore|Pex17p-Pex14p docking complex|Pex14 complex|peroxisomal protein import machinery	https://github.com/geneontology/go-ontology/issues/22100						jl	2014-07-29T14:45:28Z			GO:1990415		cellular_component											owl:Class	
GO:0033823	biolink:NamedThing	procollagen glucosyltransferase activity	Catalysis of the reaction: UDP-glucose + 5-(D-galactosyloxy)-L-lysine-procollagen = UDP + 1,2-D-glucosyl-5-D-(galactosyloxy)-L-lysine-procollagen.	tmpzr1t_l9r_go_relaxed.owl	galactosylhydroxylysine glucosyltransferase activity|UDP-glucose-collagenglucosyltransferase activity|UDP-glucose:5-(D-galactosyloxy)-L-lysine-procollagen D-glucosyltransferase activity|UDPglucose:5-(D-galactosyloxy)-L-lysine-procollagen D-glucosyltransferase activity|uridine diphosphoglucose-collagen glucosyltransferase activity|collagen glucosyltransferase activity|collagen hydroxylysyl glucosyltransferase activity|galactosylhydroxylysine-glucosyltransferase activity|galactosylhydroxylysyl glucosyltransferase activity				MetaCyc:PROCOLLAGEN-GLUCOSYLTRANSFERASE-RXN|RHEA:12576|Reactome:R-HSA-1981157|EC:2.4.1.66									molecular_function											owl:Class	
GO:0047315	biolink:NamedThing	kynurenine-glyoxylate transaminase activity	Catalysis of the reaction: L-kynurenine + glyoxylate = 4-(2-aminophenyl)-2,4-dioxobutanoate + glycine.	tmpzr1t_l9r_go_relaxed.owl	kynurenine-glyoxylate aminotransferase activity|kynurenine--glyoxylate aminotransferase activity|L-kynurenine:glyoxylate aminotransferase (cyclizing)				MetaCyc:2.6.1.63-RXN|RHEA:19249|EC:2.6.1.63|KEGG_REACTION:R01957									molecular_function											owl:Class	
GO:0051065	biolink:NamedThing	CTP reductase activity	Catalysis of the reaction: dCTP + thioredoxin disulfide + H2O = CTP + thioredoxin. Thioredoxin disulfide is the oxidized form of thioredoxin.	tmpzr1t_l9r_go_relaxed.owl	CTP reduction				EC:1.17.4.-									molecular_function											owl:Class	
GO:0008998	biolink:NamedThing	ribonucleoside-triphosphate reductase activity	Catalysis of the reaction: 2'-deoxyribonucleoside triphosphate + thioredoxin disulfide + H2O = ribonucleoside triphosphate + thioredoxin.	tmpzr1t_l9r_go_relaxed.owl	2'-deoxyribonucleoside-triphosphate:thioredoxin-disulfide 2'-oxidoreductase activity|2'-deoxyribonucleoside-triphosphate:oxidized-thioredoxin 2'-oxidoreductase activity|ribonucleotide reductase activity				MetaCyc:1.17.4.2-RXN|RHEA:12701|EC:1.17.4.2									molecular_function											owl:Class	
GO:0005402	biolink:NamedThing	carbohydrate:cation symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sugar(out) + cation(out) = sugar(in) + cation(in).	tmpzr1t_l9r_go_relaxed.owl	cation:sugar symporter activity|cation/sugar symporter activity|sugar:cation symporter activity													molecular_function											owl:Class	
GO:0003065	biolink:NamedThing	positive regulation of heart rate by epinephrine	The process in which the secretion of epinephrine into the bloodstream or released from nerve endings increases the rate of heart muscle contraction.	tmpzr1t_l9r_go_relaxed.owl	adrenaline cardiac chronotropy|adrenaline regulation of the rate of heart muscle contraction|epinephrine cardiac chronotropy|positive regulation of heart contraction rate by epinephrine|positive regulation of heart rate by adrenaline													biological_process											owl:Class	
GO:0140037	biolink:NamedThing	sumo-dependent protein binding	Binding to a protein upon sumoylation of the target protein.	tmpzr1t_l9r_go_relaxed.owl						This term should only be used when the binding is shown to require sumoylation of the target protein: the interaction needs to be tested with and without the PTM. The binding does not need to be at the site of sumoylation. It may be that the sumoylation causes a conformational change that allows binding of the protein to another region; this type of sumoylation-dependent protein binding is valid for annotation to this term.		pg	2017-05-18T06:29:27Z					molecular_function											owl:Class	
GO:0140035	biolink:NamedThing	ubiquitination-like modification-dependent protein binding	Binding to a protein upon modification by a ubiquitin-like protein of the target protein.	tmpzr1t_l9r_go_relaxed.owl						This term should only be used when the binding is shown to require a ubiquitin-like modification in the target protein: the interaction needs to be tested with and without the PTM. The binding does not need to be at the site of ubiquitin-like modification. It may be that the modification causes a conformational change that allows binding of the protein to another region; this type of modification-dependent protein binding is valid for annotation to this term.		pg	2017-05-18T06:11:27Z					molecular_function											owl:Class	
GO:1901411	biolink:NamedThing	negative regulation of tetrapyrrole biosynthetic process from glutamate	Any process that stops, prevents or reduces the frequency, rate or extent of tetrapyrrole biosynthetic process from glutamate.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of tetrapyrrole biosynthetic process from glutamate|down-regulation of tetrapyrrole anabolism from glutamate|down regulation of tetrapyrrole formation from glutamate|down-regulation of tetrapyrrole synthesis from glutamate|inhibition of tetrapyrrole formation from glutamate|down regulation of tetrapyrrole anabolism from glutamate|down-regulation of tetrapyrrole biosynthesis from glutamate|inhibition of tetrapyrrole biosynthesis from glutamate|downregulation of tetrapyrrole formation from glutamate|down-regulation of tetrapyrrole formation from glutamate|inhibition of tetrapyrrole anabolism from glutamate|negative regulation of tetrapyrrole formation from glutamate|negative regulation of tetrapyrrole synthesis from glutamate|down regulation of tetrapyrrole biosynthetic process from glutamate|inhibition of tetrapyrrole synthesis from glutamate|inhibition of tetrapyrrole biosynthetic process from glutamate|negative regulation of tetrapyrrole biosynthesis from glutamate|downregulation of tetrapyrrole anabolism from glutamate|downregulation of tetrapyrrole synthesis from glutamate|downregulation of tetrapyrrole biosynthesis from glutamate|downregulation of tetrapyrrole biosynthetic process from glutamate|down regulation of tetrapyrrole synthesis from glutamate|negative regulation of tetrapyrrole anabolism from glutamate|down regulation of tetrapyrrole biosynthesis from glutamate							tt	2012-10-01T16:22:03Z					biological_process											owl:Class	
GO:0097328	biolink:NamedThing	response to carboplatin	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carboplatin stimulus.	tmpzr1t_l9r_go_relaxed.owl								pr	2012-06-12T10:50:34Z					biological_process											owl:Class	
GO:1904144	biolink:NamedThing	phosphatidylinositol phosphate phosphatase complex	A protein complex which is capable of phosphatidylinositol phosphate phosphatase activity.	tmpzr1t_l9r_go_relaxed.owl	prostatic acid phosphatase complex					An example of this is ACPP in human (P15309) in PMID:12525165 (inferred from physical interaction).		bhm	2015-04-14T11:22:53Z					cellular_component											owl:Class	
GO:0036073	biolink:NamedThing	perichondral ossification	Intramembranous ossification from the surface of a cartilage element as the perichondrium becomes a periosteum, without replacement of cartilage.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-12-19T01:49:38Z					biological_process											owl:Class	
GO:0001957	biolink:NamedThing	intramembranous ossification	Direct ossification that occurs within mesenchyme or an accumulation of relatively unspecialized cells.	tmpzr1t_l9r_go_relaxed.owl	dermal ossification|intramembranous bone ossification				Wikipedia:Intramembranous_ossification	An instance of intramembranous ossification may also be classified as metaplastic; the former classifies based on tissue type location, and the latter based on mechanism/cell division.								biological_process											owl:Class	
GO:0008714	biolink:NamedThing	AMP nucleosidase activity	Catalysis of the reaction: AMP + H(2)O = D-ribose 5-phosphate + adenine.	tmpzr1t_l9r_go_relaxed.owl	AMP phosphoribohydrolase activity|adenylate nucleosidase activity|adenosine monophosphate nucleosidase activity				RHEA:20129|MetaCyc:AMP-NUCLEOSID-RXN|KEGG_REACTION:R00182|EC:3.2.2.4									molecular_function											owl:Class	
GO:1903995	biolink:NamedThing	regulation of non-membrane spanning protein tyrosine kinase activity	Any process that modulates the frequency, rate or extent of non-membrane spanning protein tyrosine kinase activity.	tmpzr1t_l9r_go_relaxed.owl	regulation of cytoplasmic protein tyrosine kinase activity|regulation of janus kinase 2 activity|regulation of Bruton's tyrosine kinase activity|regulation of ATP:protein-tyrosine O-phosphotransferase activity|regulation of p60c-src protein tyrosine kinase activity|regulation of janus kinase 3 activity|regulation of non-specific protein-tyrosine kinase activity|regulation of focal adhesion kinase activity|regulation of janus kinase 1 activity|regulation of ATP:protein-L-tyrosine O-phosphotransferase (non-specific) activity							nc	2015-03-05T16:34:35Z					biological_process											owl:Class	
GO:0140157	biolink:NamedThing	ammonium import across plasma membrane	The directed movement of an ammonium ion from outside of a cell, across the plasma membrane and into the cytosol.	tmpzr1t_l9r_go_relaxed.owl								pg	2018-01-26T12:39:56Z					biological_process											owl:Class	
GO:0018495	biolink:NamedThing	2-hydroxycyclohexane-1-carboxyl-CoA dehydrogenase activity	Catalysis of the reaction: 2-hydroxycyclohexane-1-carboxyl-CoA = 2 H+ + 2 e- + 2-ketocyclohexane-1-carboxyl-CoA.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0192									molecular_function											owl:Class	
GO:0034011	biolink:NamedThing	L-cysteate sulfo-lyase activity	Catalysis of the reaction: L-cysteate + H(2)O = NH(4)(+) + pyruvate + sulfite.	tmpzr1t_l9r_go_relaxed.owl	L-cysteate sulfo-lyase (deaminating) activity|CuyA|L-cysteate bisulfite-lyase (deaminating; pyruvate-forming) activity				KEGG_REACTION:R07634|EC:4.4.1.25|MetaCyc:4.4.1.25-RXN|RHEA:13441									molecular_function											owl:Class	
GO:2001227	biolink:NamedThing	quercitrin binding	Binding to quercitrin.	tmpzr1t_l9r_go_relaxed.owl								tb	2011-11-18T09:58:37Z					molecular_function											owl:Class	
GO:0043110	biolink:NamedThing	rDNA spacer replication fork barrier binding	Binding to replication fork barriers found in rDNA spacers, sites that inhibit replication forks in the direction opposite to rDNA transcription.	tmpzr1t_l9r_go_relaxed.owl	RFB binding													molecular_function											owl:Class	
GO:0018749	biolink:NamedThing	(3,5-dichlorophenylurea)acetate amidohydrolase activity	Catalysis of the reaction: (3,5-dichlorophenylurea)acetate + OH- = 3,5-dichloroaniline + N-carboxyglycine.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0708									molecular_function											owl:Class	
GO:0033086	biolink:NamedThing	negative regulation of extrathymic T cell differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of extrathymic T cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of extrathymic T cell development					Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.								biological_process											owl:Class	
GO:0015514	biolink:NamedThing	nitrite efflux transmembrane transporter activity	Enables the transfer of nitrite from the inside of the cell to the outside of the cell across a membrane.	tmpzr1t_l9r_go_relaxed.owl	nitrite extrusion permease activity													molecular_function											owl:Class	
GO:1905790	biolink:NamedThing	regulation of mechanosensory behavior	Any process that modulates the frequency, rate or extent of mechanosensory behavior.	tmpzr1t_l9r_go_relaxed.owl	regulation of behavioural response to mechanical stimulus|regulation of behavioral response to mechanical stimulus|regulation of mechanosensory behaviour							hbye	2017-01-09T15:17:07Z					biological_process											owl:Class	
GO:1990418	biolink:NamedThing	response to insulin-like growth factor stimulus	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin-like growth factor stimulus.	tmpzr1t_l9r_go_relaxed.owl								sl	2014-07-14T22:47:59Z					biological_process											owl:Class	
GO:0009249	biolink:NamedThing	protein lipoylation	The lipoylation of peptidyl-lysine to form peptidyl-N6-lipoyl-L-lysine.	tmpzr1t_l9r_go_relaxed.owl	protein-lipoic acid cofactor linkage|peptidyl-lysine lipoylation											GO:0018055		biological_process											owl:Class	
GO:0106229	biolink:NamedThing	histone glutaryltransferase activity	Catalysis of the reaction: glutaryl-CoA + histone = CoA + H+ + N6-glutaryl-histone.	tmpzr1t_l9r_go_relaxed.owl								hjd	2019-10-17T19:01:48Z					molecular_function											owl:Class	
GO:0106228	biolink:NamedThing	peptide glutaryltransferase activity	Catalysis of the reaction: glutaryl-CoA + L-lysyl-[protein] = CoA + H+ + N6-glutaryl-L-lysyl-[protein].	tmpzr1t_l9r_go_relaxed.owl					RHEA:18009			hjd	2019-10-17T18:58:56Z					molecular_function											owl:Class	
GO:1902437	biolink:NamedThing	positive regulation of male mating behavior	Any process that activates or increases the frequency, rate or extent of male mating behavior.	tmpzr1t_l9r_go_relaxed.owl	up regulation of male mating behavior|up-regulation of male mating behavior|activation of male mating behavior|upregulation of male mating behavior							mm2	2013-10-09T15:50:14Z					biological_process											owl:Class	
GO:0033968	biolink:NamedThing	glutaryl-7-aminocephalosporanic-acid acylase activity	Catalysis of the reaction: (7R)-7-(4-carboxybutanamido)cephalosporanate + H2O = (7R)-7-aminocephalosporanate + glutarate.	tmpzr1t_l9r_go_relaxed.owl	CA|GA|(7R)-7-(4-carboxybutanamido)cephalosporanate amidohydrolase activity|glutaryl-7-ACA acylase activity|cephalosporin C acylase activity|7beta-(4-carboxybutanamido)cephalosporanic acid acylase activity|GL-7-ACA acylase activity|glutaryl-7-aminocephalosporanic acid acylase activity|cephalosporin acylase activity|GCA				EC:3.5.1.93|MetaCyc:3.5.1.93-RXN|RHEA:23508									molecular_function											owl:Class	
GO:0050555	biolink:NamedThing	2-hydroxypropyl-CoM lyase activity	Catalysis of the reactions: (R)-2-hydroxypropyl-CoM = H-S-CoM + (R)-1,2-epoxypropane, and (S)-2-hydroxypropyl-CoM = H-S-CoM + (S)-1,2-epoxypropane.	tmpzr1t_l9r_go_relaxed.owl	2-hydroxypropyl-CoM:2-mercaptoethanesulfonate lyase (epoxyalkane-ring-forming)|epoxyalkyl:CoM transferase activity|epoxypropane:coenzyme M transferase activity|(R)-[or (S)-]2-hydroxypropyl-CoM:2-mercaptoethanesulfonate lyase (epoxyalkane-ring-forming)|(R)-2-hydroxypropyl-CoM 2-mercaptoethanesulfonate lyase (cyclizing; epoxyalkane-ring-forming)|epoxypropyl:CoM transferase activity|epoxyalkane:CoM transferase activity|coenzyme M-epoxyalkane ligase activity|epoxyalkane:2-mercaptoethanesulfonate transferase activity|epoxyalkane:coenzyme M transferase activity|EaCoMT activity				RHEA:19421|UM-BBD_enzymeID:e0538|MetaCyc:4.2.99.19-RXN|EC:4.4.1.23									molecular_function											owl:Class	
GO:0009748	biolink:NamedThing	hexokinase-independent signaling	A series of molecular signals mediated by hexose and independent of hexokinase.	tmpzr1t_l9r_go_relaxed.owl	hexokinase-independent signalling													biological_process											owl:Class	
GO:1903367	biolink:NamedThing	positive regulation of fear response	Any process that activates or increases the frequency, rate or extent of fear response.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of physiological fear response|up regulation of fear response|activation of fear response|up-regulation of physiological fear response|up-regulation of fear response|up regulation of physiological fear response|upregulation of fear response|upregulation of physiological fear response|activation of physiological fear response							mr	2014-08-21T23:21:53Z					biological_process											owl:Class	
GO:1902824	biolink:NamedThing	positive regulation of late endosome to lysosome transport	Any process that activates or increases the frequency, rate or extent of late endosome to lysosome transport.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of late endosome to lysosome transport|up regulation of late endosome to lysosome transport|activation of late endosome to lysosome transport|upregulation of late endosome to lysosome transport							pad	2014-03-31T10:08:57Z					biological_process											owl:Class	
GO:0002941	biolink:NamedThing	synoviocyte proliferation	The multiplication or reproduction of synoviocytes by cell division, resulting in the expansion of their population. A synoviocyte is a fibroblast-like cell found in synovial tissues.	tmpzr1t_l9r_go_relaxed.owl								hjd	2012-11-16T14:25:45Z					biological_process											owl:Class	
GO:1905169	biolink:NamedThing	regulation of protein localization to phagocytic vesicle	Any process that modulates the frequency, rate or extent of protein localization to phagocytic vesicle.	tmpzr1t_l9r_go_relaxed.owl	regulation of protein localisation to phagocytic vesicle|regulation of protein localization in phagocytic vesicle|regulation of protein localisation to phagosome|regulation of protein recruitment to phagosome|regulation of protein localisation in phagocytic vesicle							bf	2016-05-02T18:38:13Z					biological_process											owl:Class	
GO:0042880	biolink:NamedThing	D-glucuronate transmembrane transporter activity	Enables the transfer of D-glucuronate, the D-enantiomer of glucuronate, from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0060566	biolink:NamedThing	positive regulation of DNA-templated transcription, termination	Any process that increases the rate, frequency or extent of DNA-templated transcription termination, the process in which transcription is completed; the formation of phosphodiester bonds ceases, the RNA-DNA hybrid dissociates, and RNA polymerase releases the DNA.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of transcription termination, DNA-dependent|positive regulation of DNA-dependent transcription, termination|positive regulation of termination of DNA-dependent transcription							dph	2009-04-29T02:54:50Z					biological_process											owl:Class	
GO:1902298	biolink:NamedThing	cell cycle DNA replication maintenance of fidelity	Any maintenance of fidelity that is involved in cell cycle DNA replication.	tmpzr1t_l9r_go_relaxed.owl	maintenance of fidelity involved in cell cycle DNA replication|maintenance of fidelity during DNA-dependent DNA replication involved in cell cycle DNA replication							jl	2013-07-10T11:47:19Z					biological_process											owl:Class	
GO:1990736	biolink:NamedThing	regulation of vascular associated smooth muscle cell membrane depolarization	Any process that modulates the establishment or extent of a membrane potential in the depolarizing direction away from the resting potential in a vascular smooth muscle cell.	tmpzr1t_l9r_go_relaxed.owl	regulation of vascular smooth muscle cell membrane depolarization							sl	2015-04-29T22:33:19Z					biological_process											owl:Class	
GO:0046032	biolink:NamedThing	ADP catabolic process	The chemical reactions and pathways resulting in the breakdown of ADP, adenosine 5'-diphosphate.	tmpzr1t_l9r_go_relaxed.owl	ADP catabolism|ADP breakdown|ADP degradation													biological_process											owl:Class	
GO:1904743	biolink:NamedThing	negative regulation of telomeric DNA binding	Any process that stops, prevents or reduces the frequency, rate or extent of telomeric DNA binding.	tmpzr1t_l9r_go_relaxed.owl	inhibition of telomeric DNA binding|down regulation of telomeric DNA binding|down regulation of telomere binding|down-regulation of telomeric DNA binding|down-regulation of telomere binding|downregulation of telomere binding|negative regulation of telomere binding|inhibition of telomeric repeat binding|inhibition of telomere binding|negative regulation of telomeric repeat binding|down-regulation of telomeric repeat binding|downregulation of telomeric DNA binding|downregulation of telomeric repeat binding|down regulation of telomeric repeat binding							nc	2015-10-19T12:18:55Z					biological_process											owl:Class	
GO:0032064	biolink:NamedThing	positive regulation of translational initiation in response to osmotic stress	Any process that activates or increases the frequency, rate or extent of translation initiation, as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell.	tmpzr1t_l9r_go_relaxed.owl	stimulation of translation initiation in response to osmotic stress|upregulation of translation initiation in response to osmotic stress|activation of translation initiation in response to osmotic stress|up-regulation of translation initiation in response to osmotic stress|up regulation of translation initiation in response to osmotic stress													biological_process											owl:Class	
GO:0044867	biolink:NamedThing	modulation by host of viral catalytic activity	The process in which a host organism effects a change in the enzyme activity of a virus with which it is infected.	tmpzr1t_l9r_go_relaxed.owl								jl	2014-09-18T11:29:25Z					biological_process											owl:Class	
GO:0044868	biolink:NamedThing	modulation by host of viral molecular function	A process in which a host organism modulates the frequency, rate or extent of any molecular function being mediated by a virus with which it is infected.	tmpzr1t_l9r_go_relaxed.owl								jl	2014-09-18T13:34:27Z					biological_process											owl:Class	
GO:1901687	biolink:NamedThing	glutathione derivative biosynthetic process	The chemical reactions and pathways resulting in the formation of glutathione derivative.	tmpzr1t_l9r_go_relaxed.owl	glutathione derivative anabolism|glutathione derivative synthesis|glutathione derivative formation|glutathione derivative biosynthesis							pr	2012-12-05T11:57:20Z					biological_process											owl:Class	
GO:0002463	biolink:NamedThing	central tolerance induction to nonself antigen	Tolerance induction to nonself antigens in the central lymphoid organs.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0030145	biolink:NamedThing	manganese ion binding	Binding to a manganese ion (Mn).	tmpzr1t_l9r_go_relaxed.owl	manganese binding|Mn binding													molecular_function											owl:Class	
GO:0036224	biolink:NamedThing	pairing center	A special chromosome region located towards one end of a chromosome that contains dispersed copies of short, repetitive DNA sequences and functions as a cis-acting element essential for presynaptic homologous chromosome pairing and chromosome-nuclear envelope attachment.	tmpzr1t_l9r_go_relaxed.owl	homolog recognition region							bf	2012-05-09T02:28:53Z					cellular_component											owl:Class	
GO:1902755	biolink:NamedThing	sulfurated eukaryotic molybdenum cofactor(2-) metabolic process	The chemical reactions and pathways involving sulfurated eukaryotic molybdenum cofactor(2-).	tmpzr1t_l9r_go_relaxed.owl	sulfurated eukaryotic molybdenum cofactor(2-) metabolism							dph	2014-03-05T23:29:13Z					biological_process											owl:Class	
GO:0033901	biolink:NamedThing	ribonuclease V activity	Catalysis of the hydrolysis of poly(A), forming oligoribonucleotides and ultimately 3'-AMP.	tmpzr1t_l9r_go_relaxed.owl	endoribonuclease V activity				EC:3.1.27.8|MetaCyc:3.1.27.8-RXN									molecular_function											owl:Class	
GO:1902787	biolink:NamedThing	cellular response to dodecane	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dodecane stimulus.	tmpzr1t_l9r_go_relaxed.owl								tt	2014-03-21T13:41:52Z					biological_process											owl:Class	
GO:1902786	biolink:NamedThing	response to dodecane	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dodecane stimulus.	tmpzr1t_l9r_go_relaxed.owl								tt	2014-03-21T13:41:36Z					biological_process											owl:Class	
GO:0017011	biolink:NamedThing	protein-phycoerythrobilin linkage	The linkage of the chromophore phycoerythrobilin to phycoerythrins.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0132									biological_process											owl:Class	
GO:0002410	biolink:NamedThing	plasmacytoid dendritic cell chemotaxis	The movement of a plasmacytoid dendritic cell in response to an external stimulus.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0070032	biolink:NamedThing	synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex	A SNARE complex that contains synaptobrevin 2 (VAMP2), SNAP-25, syntaxin 1a, and complexin I (or orthologs thereof).	tmpzr1t_l9r_go_relaxed.owl	SNARE complex (Vamp2, Snap25, Stx1a, Cplx1)|Vamp2-Snap25-Stx1a-Cplx1 complex													cellular_component											owl:Class	
GO:0001014	biolink:NamedThing	snoRNA transcription by RNA polymerase III	The synthesis of small nucleolar RNA (snoRNA) from a DNA template by RNA polymerase III, originating at a type 2 RNA polymerase III promoter.	tmpzr1t_l9r_go_relaxed.owl	snoRNA transcription from a type 2 RNA polymerase III promoter							krc	2010-08-18T07:13:45Z					biological_process											owl:Class	
GO:0050801	biolink:NamedThing	ion homeostasis	Any process involved in the maintenance of an internal steady state of ions within an organism or cell.	tmpzr1t_l9r_go_relaxed.owl	regulation of ion homeostasis|electrolyte homeostasis|negative regulation of crystal formation											GO:2000021		biological_process											owl:Class	
GO:0033795	biolink:NamedThing	betaine reductase activity	Catalysis of the reaction: acetyl phosphate + trimethylamine + thioredoxin disulfide = N,N,N-trimethylglycine + phosphate + thioredoxin.	tmpzr1t_l9r_go_relaxed.owl	acetyl-phosphate trimethylamine:thioredoxin disulfide oxidoreductase (N,N,N-trimethylglycine-forming) activity				EC:1.21.4.4|RHEA:11848									molecular_function											owl:Class	
GO:0080058	biolink:NamedThing	protein deglutathionylation	The protein modification process in which a glutathione molecule is removed from a protein amino acid by breaking a disulfide linkage.	tmpzr1t_l9r_go_relaxed.owl	protein amino acid deglutathionylation							dhl	2009-04-13T02:48:06Z					biological_process											owl:Class	
GO:0050319	biolink:NamedThing	tartrate decarboxylase activity	Catalysis of the reaction: L-tartrate + H(+) = D-glycerate + CO(2).	tmpzr1t_l9r_go_relaxed.owl	(R,R)-tartrate carboxy-lyase (D-glycerate-forming)|(R,R)-tartrate carboxy-lyase activity				KEGG_REACTION:R01751|RHEA:13317|MetaCyc:TARTRATE-DECARBOXYLASE-RXN|EC:4.1.1.73									molecular_function											owl:Class	
GO:0006715	biolink:NamedThing	farnesol biosynthetic process	The chemical reactions and pathways resulting in the formation of the sesquiterpenoid alcohol farnesol, 3,7,11-trimethyl-2,6,10,dodecatrien-1-ol.	tmpzr1t_l9r_go_relaxed.owl	farnesol formation|farnesol anabolism|farnesol biosynthesis|farnesol synthesis													biological_process											owl:Class	
GO:1901470	biolink:NamedThing	negative regulation of syringal lignin catabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of syringal lignin catabolic process.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of syringal lignin degradation|inhibition of syringal lignin catabolism|down-regulation of S-lignin catabolic process|negative regulation of syringal lignin catabolism|downregulation of syringal lignin degradation|down-regulation of syringal lignin catabolic process|down-regulation of syringal lignin degradation|inhibition of S-lignin catabolic process|down regulation of syringal lignin degradation|inhibition of syringal lignin catabolic process|down-regulation of syringal lignin breakdown|down-regulation of syringal lignin catabolism|downregulation of S-lignin catabolic process|down regulation of syringal lignin catabolism|downregulation of syringal lignin catabolic process|down regulation of syringal lignin catabolic process|down regulation of syringal lignin breakdown|inhibition of syringal lignin degradation|inhibition of syringal lignin breakdown|negative regulation of S-lignin catabolic process|negative regulation of syringal lignin breakdown|downregulation of syringal lignin breakdown|downregulation of syringal lignin catabolism|down regulation of S-lignin catabolic process							tt	2012-10-02T14:42:21Z					biological_process											owl:Class	
GO:2000318	biolink:NamedThing	positive regulation of T-helper 17 type immune response	Any process that activates or increases the frequency, rate or extent of T-helper 17 type immune response.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of Th17 immune response							mah	2011-01-18T01:33:24Z					biological_process											owl:Class	
GO:1902987	biolink:NamedThing	negative regulation of lysine biosynthetic process via aminoadipic acid	Any process that stops, prevents or reduces the frequency, rate or extent of lysine biosynthetic process via aminoadipic acid.	tmpzr1t_l9r_go_relaxed.owl	downregulation of lysine biosynthesis, aminoadipic acid pathway|inhibition of lysine biosynthetic process via aminoadipic acid|down-regulation of lysine biosynthetic process via aminoadipic acid|negative regulation of lysine biosynthesis, aminoadipic acid pathway|negative regulation of lysine anabolism via aminoadipic acid|negative regulation of lysine biosynthetic process, aminoadipic pathway|down regulation of lysine anabolism via aminoadipic acid|inhibition of lysine biosynthesis, aminoadipic acid pathway|inhibition of lysine biosynthesis, aminoadipic pathway|downregulation of lysine formation via aminoadipic acid|down regulation of lysine biosynthesis, aminoadipic pathway|down regulation of lysine biosynthesis, aminoadipic acid pathway|down-regulation of lysine biosynthetic process, aminoadipic acid pathway|downregulation of lysine biosynthetic process, aminoadipic acid pathway|down-regulation of lysine formation via aminoadipic acid|down regulation of lysine formation via aminoadipic acid|down-regulation of lysine anabolism via aminoadipic acid|inhibition of lysine synthesis via aminoadipic acid|down-regulation of lysine biosynthetic process, aminoadipic pathway|downregulation of lysine anabolism via aminoadipic acid|downregulation of lysine synthesis via aminoadipic acid|negative regulation of lysine biosynthesis, aminoadipic pathway|down-regulation of lysine biosynthesis, aminoadipic acid pathway|inhibition of lysine biosynthetic process, aminoadipic acid pathway|inhibition of lysine biosynthetic process, aminoadipic pathway|negative regulation of lysine biosynthetic process, aminoadipic acid pathway|down regulation of lysine biosynthetic process, aminoadipic acid pathway|down-regulation of lysine synthesis via aminoadipic acid|downregulation of lysine biosynthesis, aminoadipic pathway|downregulation of lysine biosynthetic process via aminoadipic acid|negative regulation of lysine synthesis via aminoadipic acid|negative regulation of lysine formation via aminoadipic acid|downregulation of lysine biosynthetic process, aminoadipic pathway|inhibition of lysine formation via aminoadipic acid|down-regulation of lysine biosynthesis, aminoadipic pathway|down regulation of lysine biosynthetic process via aminoadipic acid|inhibition of lysine anabolism via aminoadipic acid|down regulation of lysine synthesis via aminoadipic acid|down regulation of lysine biosynthetic process, aminoadipic pathway							al	2014-05-07T08:07:15Z					biological_process											owl:Class	
GO:0002952	biolink:NamedThing	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity	Catalysis of the reaction (4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione = 3-hydroxy-5-phosphonooxypentane-2,4-dione.	tmpzr1t_l9r_go_relaxed.owl	phospho-AI-2 isomerase activity													molecular_function											owl:Class	
GO:0051752	biolink:NamedThing	phosphoglucan, water dikinase activity	Catalysis of the reaction: ATP + [phospho-alpha-glucan] + H2O = AMP + O-phospho-[phospho-alpha-glucan] + phosphate.	tmpzr1t_l9r_go_relaxed.owl	OK1|PWD|ATP:phospho-alpha-glucan, water phosphotransferase activity				EC:2.7.9.5|MetaCyc:2.7.9.5-RXN									molecular_function											owl:Class	
GO:0097234	biolink:NamedThing	epidermal lamellar body membrane	The lipid bilayer surrounding an epidermal lamellar body, a specialized secretory organelle found in keratinocytes and involved in the formation of an impermeable, lipid-containing membrane that serves as a water barrier and is required for correct skin barrier function.	tmpzr1t_l9r_go_relaxed.owl								pr	2012-01-26T10:32:13Z					cellular_component											owl:Class	
GO:0097232	biolink:NamedThing	lamellar body membrane	The lipid bilayer surrounding a lamellar body. A lamellar body is a membrane-bounded organelle, specialized for the storage and secretion of various substances (surfactant phospholipids, glycoproteins and acid phosphates) which are arranged in the form of tightly packed, concentric, membrane sheets or lamellae. Has some similar properties to, but is distinct from, a lysosome.	tmpzr1t_l9r_go_relaxed.owl								pr	2012-01-26T10:28:42Z					cellular_component											owl:Class	
GO:0102220	biolink:NamedThing	hydrogenase activity (NAD+, ferredoxin)	Catalysis of the reaction: 2 dihydrogen + NAD + 2 an oxidized ferredoxin = NADH + 3 H+ + 2 a reduced ferredoxin.	tmpzr1t_l9r_go_relaxed.owl					EC:1.12.1.4|RHEA:30279|MetaCyc:RXN-12215									molecular_function											owl:Class	
GO:0140084	biolink:NamedThing	sexual macrocyst formation	The fusion of haploid amoebae cells with matching mating types to form a larger cell, which ingests additional amoebae and forms a cellulose wall. The resulting macrocyst undergoes recombination and meiosis followed by release of haploid amoebae. An example of this process can be found in Dictyostelium discoideum.	tmpzr1t_l9r_go_relaxed.owl	sexual fusion|macrocyst formation							pg	2017-08-14T20:11:03Z					biological_process											owl:Class	
GO:0019953	biolink:NamedThing	sexual reproduction	A reproduction process that creates a new organism by combining the genetic material of two gametes, which may come from two organisms or from a single organism, in the case of self-fertilizing hermaphrodites, e.g. C. elegans, or self-fertilization in plants. It occurs both in eukaryotes and prokaryotes: in multicellular eukaryotic organisms, an individual is created anew; in prokaryotes, the initial cell has additional or transformed genetic material. In a process called genetic recombination, genetic material (DNA) originating from two gametes join up so that homologous sequences are aligned with each other, and this is followed by exchange of genetic information. After the new recombinant chromosome is formed, it is passed on to progeny.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Sexual_reproduction	Sexual reproduction may be seen as the regular alternation, in the life cycle of haplontic, diplontic and diplohaplontic organisms, of meiosis and fertilization which provides for the production offspring. In diplontic organisms there is a life cycle in which the products of meiosis behave directly as gametes, fusing to form a zygote from which the diploid, or sexually reproductive polyploid, adult organism will develop. In diplohaplontic organisms a haploid phase (gametophyte) exists in the life cycle between meiosis and fertilization (e.g. higher plants, many algae and Fungi); the products of meiosis are spores that develop as haploid individuals from which haploid gametes develop to form a diploid zygote; diplohaplontic organisms show an alternation of haploid and diploid generations. In haplontic organisms meiosis occurs in the zygote, giving rise to four haploid cells (e.g. many algae and protozoa), only the zygote is diploid and this may form a resistant spore, tiding organisms over hard times.								biological_process											owl:Class	
GO:0071620	biolink:NamedThing	phosphorylation of RNA polymerase II C-terminal domain serine 5 residues	The process of introducing a phosphate group onto a serine residue at position 5 within the heptapeptide repeat (YSPTSPS) of the C-terminal domain of RNA polymerase II. Typically, phosphorylation of serine 5 (Ser5) occurs near the 5' ends of genes. It is generally still observed in the middle of genes, overlapping with phosphorylation of serine 2, but is generally not present at the 3' ends of genes. In vivo, Ser5 phosphorylation occurs primarily through the action of TFIIH (KIN28 in S. cerevisiae, CKD7 in metazoans).	tmpzr1t_l9r_go_relaxed.owl								mah	2010-02-09T02:39:52Z					biological_process											owl:Class	
GO:0033460	biolink:NamedThing	GAG codon-amino acid adaptor activity	A triplet codon-amino acid adaptor activity that recognizes a GAG codon.	tmpzr1t_l9r_go_relaxed.owl	glutamic acid tRNA					Note that in the standard genetic code, GAG codes for glutamic acid.								molecular_function											owl:Class	
GO:0035247	biolink:NamedThing	peptidyl-arginine omega-N-methylation	The addition of a methyl group onto a terminal nitrogen (omega nitrogen) atom of an arginine residue in a protein.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0068|RESID:AA0067|RESID:AA0069									biological_process											owl:Class	
GO:0035246	biolink:NamedThing	peptidyl-arginine N-methylation	The addition of a methyl group onto a nitrogen atom of an arginine residue in a protein.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1900017	biolink:NamedThing	positive regulation of cytokine production involved in inflammatory response	Any process that activates or increases the frequency, rate or extent of cytokine production involved in inflammatory response.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of cytokine production involved in acute inflammatory response|up regulation of cytokine production involved in acute inflammatory response|up regulation of cytokine production involved in inflammatory response							rph	2012-01-11T09:34:35Z					biological_process											owl:Class	
GO:0043160	biolink:NamedThing	acrosomal lumen	The volume enclosed within the acrosome membrane.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0043202	biolink:NamedThing	lysosomal lumen	The volume enclosed within the lysosomal membrane.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0010955	biolink:NamedThing	negative regulation of protein processing	Any process that decreases the rate, frequency or extent of protein maturation by peptide bond cleavage.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of protein maturation by peptide bond cleavage							tb	2009-04-27T12:10:19Z					biological_process											owl:Class	
GO:0010886	biolink:NamedThing	positive regulation of cholesterol storage	Any process that increases the rate or extent of cholesterol storage. Cholesterol storage is the accumulation and maintenance in cells or tissues of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of cholesterol sequestration													biological_process											owl:Class	
GO:0021940	biolink:NamedThing	positive regulation of cerebellar granule cell precursor proliferation	The process that activates or increases the rate or extent of granule cell precursor proliferation.	tmpzr1t_l9r_go_relaxed.owl	activation of granule cell precursor proliferation|stimulation of granule cell precursor proliferation|up regulation of granule cell precursor proliferation|upregulation of granule cell precursor proliferation|up-regulation of granule cell precursor proliferation													biological_process											owl:Class	
GO:0120198	biolink:NamedThing	positive regulation of imaginal disc-derived wing size	Any process that increases the size of an imaginal disc-derived wing.	tmpzr1t_l9r_go_relaxed.owl								krc	2019-04-30T21:47:06Z					biological_process											owl:Class	
GO:0071223	biolink:NamedThing	cellular response to lipoteichoic acid	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipoteichoic acid stimulus; lipoteichoic acid is a major component of the cell wall of gram-positive bacteria and typically consists of a chain of glycerol-phosphate repeating units linked to a glycolipid anchor.	tmpzr1t_l9r_go_relaxed.owl	cellular response to LTA							mah	2009-12-03T01:31:00Z					biological_process											owl:Class	
GO:1900957	biolink:NamedThing	negative regulation of 17-methylnonadec-1-ene biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of 17-methylnonadec-1-ene biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	downregulation of 17-methylnonadec-1-ene biosynthetic process|down regulation of 17-methylnonadec-1-ene synthesis|inhibition of 17-methylnonadec-1-ene biosynthetic process|down regulation of 17-methylnonadec-1-ene anabolism|downregulation of 17-methylnonadec-1-ene formation|negative regulation of 17-methylnonadec-1-ene biosynthesis|inhibition of 17-methylnonadec-1-ene anabolism|down-regulation of 17-methylnonadec-1-ene anabolism|negative regulation of 17-methylnonadec-1-ene formation|inhibition of 17-methylnonadec-1-ene synthesis|down-regulation of 17-methylnonadec-1-ene synthesis|down-regulation of 17-methylnonadec-1-ene biosynthetic process|down-regulation of 17-methylnonadec-1-ene formation|inhibition of 17-methylnonadec-1-ene biosynthesis|downregulation of 17-methylnonadec-1-ene synthesis|down regulation of 17-methylnonadec-1-ene formation|down regulation of 17-methylnonadec-1-ene biosynthesis|negative regulation of 17-methylnonadec-1-ene anabolism|down regulation of 17-methylnonadec-1-ene biosynthetic process|negative regulation of 17-methylnonadec-1-ene synthesis|down-regulation of 17-methylnonadec-1-ene biosynthesis|downregulation of 17-methylnonadec-1-ene anabolism|inhibition of 17-methylnonadec-1-ene formation|downregulation of 17-methylnonadec-1-ene biosynthesis							tt	2012-06-14T03:27:39Z					biological_process											owl:Class	
GO:0015128	biolink:NamedThing	gluconate transmembrane transporter activity	Enables the transfer of gluconate from one side of a membrane to the other. Gluconate is the aldonic acid derived from glucose.	tmpzr1t_l9r_go_relaxed.owl	L-idonate/D-gluconate:hydrogen symporter activity													molecular_function											owl:Class	
GO:0071768	biolink:NamedThing	mycolic acid biosynthetic process	The chemical reactions and pathways resulting in the formation of mycolic acids, beta-hydroxy fatty acids with a long alpha-alkyl side chain.	tmpzr1t_l9r_go_relaxed.owl	mycolic acid biosynthesis|mycolic acid synthesis|mycolic acid formation|mycolic acid anabolism|mycolate biosynthetic process				MetaCyc:PWYG-321			mah	2010-03-29T04:36:10Z					biological_process											owl:Class	
GO:0071767	biolink:NamedThing	mycolic acid metabolic process	The chemical reactions and pathways involving mycolic acids, beta-hydroxy fatty acids with a long alpha-alkyl side chain.	tmpzr1t_l9r_go_relaxed.owl	mycolic acid metabolism|mycolate metabolic process							mah	2010-03-29T04:33:31Z					biological_process											owl:Class	
GO:0090225	biolink:NamedThing	regulation of spindle density	Any process that modulates the number of microtubules in a given region of the spindle.	tmpzr1t_l9r_go_relaxed.owl								tb	2010-01-13T11:24:53Z					biological_process											owl:Class	
GO:1903937	biolink:NamedThing	response to acrylamide	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acrylamide stimulus.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-02-12T22:00:24Z					biological_process											owl:Class	
GO:0042763	biolink:NamedThing	intracellular immature spore	A cell or part of the cell that constitutes an early developmental stage of a spore, a small reproductive body that is highly resistant to desiccation and heat and is capable of growing into a new organism, produced especially by certain bacteria, fungi, algae, and nonflowering plants.	tmpzr1t_l9r_go_relaxed.owl	forespore													cellular_component											owl:Class	
GO:0046557	biolink:NamedThing	glucan endo-1,6-beta-glucosidase activity	Catalysis of the random hydrolysis of (1->6) linkages in (1->6)-beta-D-glucans.	tmpzr1t_l9r_go_relaxed.owl	endo-1,6-beta-glucanase activity|endo-beta-1,6-glucanase activity|1,6-beta-D-glucan glucanohydrolase activity|beta-1,6-glucanase-pustulanase activity|beta-1,6-glucanase activity|beta-1,6-glucan 6-glucanohydrolase activity|endo-1,6-beta-D-glucanase activity|endo-(1,6)-beta-D-glucanase activity|beta-1,6-glucan hydrolase activity|beta-1->6-glucan hydrolase activity|endo-(1->6)-beta-D-glucanase activity				MetaCyc:3.2.1.75-RXN|EC:3.2.1.75									molecular_function											owl:Class	
GO:0070139	biolink:NamedThing	SUMO-specific endopeptidase activity	Catalysis of the hydrolysis of peptide bonds between an alpha-carboxyl group and an alpha-amino group within the small conjugating protein SUMO.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-2990842|Reactome:R-HSA-2993763|Reactome:R-HSA-2990840									molecular_function											owl:Class	
GO:0016929	biolink:NamedThing	SUMO-specific protease activity	Catalysis of the hydrolysis of peptide or isopeptide bonds within SUMO, or between the SUMO and a larger protein to which it has been conjugated.	tmpzr1t_l9r_go_relaxed.owl	ULP|SUSP					This term should not be used for direct manual annotation because the supporting experiments should always distinguish whether the activity is part of maturation or SUMO removal.								molecular_function											owl:Class	
GO:0034782	biolink:NamedThing	dimethylmalonate decarboxylase activity	Catalysis of the reaction: dimethylmalonate + H+ = isobutyrate + CO2.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r1031									molecular_function											owl:Class	
GO:0085037	biolink:NamedThing	extrahaustorial membrane	The membrane surrounding the symbiont haustorium during symbiosis, derived from the host plasma membrane.	tmpzr1t_l9r_go_relaxed.owl						See also: haustorium ; GO:0085035 and extrahaustorial matrix ; GO:0085036.		jl	2010-07-27T04:00:49Z					cellular_component											owl:Class	
GO:0000460	biolink:NamedThing	maturation of 5.8S rRNA	Any process involved in the maturation of a precursor 5.8S ribosomal RNA (rRNA) molecule into a mature 5.8S rRNA molecule.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0048255	biolink:NamedThing	mRNA stabilization	Prevention of degradation of mRNA molecules. In the absence of compensating changes in other processes, the slowing of mRNA degradation can result in an overall increase in the population of active mRNA molecules.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0043286	biolink:NamedThing	regulation of poly(3-hydroxyalkanoate) biosynthetic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of poly(3-hydroxyalkanoates), polyesters of 3-hydroxyacids produced as intracellular granules by a large variety of bacteria.	tmpzr1t_l9r_go_relaxed.owl	regulation of PHA|regulation of poly(3-hydroxyalkanoate) formation|regulation of poly(3-hydroxyalkanoate) anabolism|regulation of poly(3-hydroxyalkanoate) synthesis|regulation of poly(3-hydroxyalkanoate) biosynthesis													biological_process											owl:Class	
GO:0042283	biolink:NamedThing	dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase activity	Catalysis of the addition of the second glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation; the transfer of glucose from dolichyl phosphate glucose (Dol-P-Glc) on to the lipid-linked oligosaccharide Glc(1)Man(9)GlcNAc(2)-PP-Dol.	tmpzr1t_l9r_go_relaxed.owl	dolichyl-P-Glc:Glc1Man9GlcNAc2-PP-dolichyl glucosyltransferase activity				EC:2.4.1.265|MetaCyc:RXN-5471|RHEA:31307									molecular_function											owl:Class	
GO:0051112	biolink:NamedThing	peptidyl-histidine adenylylation, to form peptidyl-1'-(phospho-5'-adenosine)-L-histidine	The adenylylation of peptidyl-histidine to form peptidyl-1'-(phospho-5'-adenosine)-L-histidine (otherwise known as tau-AMP-histidine, tele-AMP-histidine).	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0371									biological_process											owl:Class	
GO:0030274	biolink:NamedThing	LIM domain binding	Binding to a LIM domain (for Lin-11 Isl-1 Mec-3) of a protein, a domain with seven conserved cysteine residues and a histidine, that binds two zinc ions and acts as an interface for protein-protein interactions.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0016446	biolink:NamedThing	somatic hypermutation of immunoglobulin genes	Mutations occurring somatically that result in amino acid changes in the rearranged V regions of immunoglobulins.	tmpzr1t_l9r_go_relaxed.owl	somatic hypermutation of antibody genes													biological_process											owl:Class	
GO:0102200	biolink:NamedThing	N-acetylphosphatidylethanolamine-hydrolysing phospholipase activity	Catalysis of the reaction: H2O + an N-acylphosphatidylethanolamine = H+ + an N-acylethanolamine + a 1,2-diacyl-sn-glycerol 3-phosphate.	tmpzr1t_l9r_go_relaxed.owl					EC:3.1.4.54|MetaCyc:RXN-12116|RHEA:33159									molecular_function											owl:Class	
GO:1905219	biolink:NamedThing	regulation of platelet formation	Any process that modulates the frequency, rate or extent of platelet formation.	tmpzr1t_l9r_go_relaxed.owl	regulation of platelet extrusion							sl	2016-06-06T22:15:46Z					biological_process											owl:Class	
GO:0045479	biolink:NamedThing	vesicle targeting to fusome	The recruitment of vesicles to the fusome. The vesicles become the fusome tubule network and are necessary for the assembly of the fusome.	tmpzr1t_l9r_go_relaxed.owl	vesicle-fusome targeting													biological_process											owl:Class	
GO:1905684	biolink:NamedThing	regulation of plasma membrane repair	Any process that modulates the frequency, rate or extent of plasma membrane repair.	tmpzr1t_l9r_go_relaxed.owl								bhm	2016-11-14T10:30:31Z					biological_process											owl:Class	
GO:0090448	biolink:NamedThing	glucosinolate:proton symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucosinolate(out) + H+(out) = glucosinolate(in) + H+(in).	tmpzr1t_l9r_go_relaxed.owl	glucosinolate:hydrogen symporter activity							tb	2012-09-07T16:10:37Z					molecular_function											owl:Class	
GO:0034915	biolink:NamedThing	2-methylhexanoyl-CoA C-acetyltransferase activity	Catalysis of the reaction: 4-methyl-3-oxooctanoyl-CoA + CoA = acetyl-CoA + 2-methylhexanoyl-CoA.	tmpzr1t_l9r_go_relaxed.owl					EC:2.3.1.-|UM-BBD_reactionID:r0927									molecular_function											owl:Class	
GO:0062048	biolink:NamedThing	lymphotoxin complex	A homo- or heterotrimeric protein containing complex consisting of alpha and beta lymphotoxin subunits in different stoichiometric combinations.	tmpzr1t_l9r_go_relaxed.owl	lymphotoxin alpha-beta							dph	2018-05-18T18:34:55Z					cellular_component											owl:Class	
GO:1904273	biolink:NamedThing	L-alanine import across plasma membrane	The directed import of L-alanine from the extracellular region across the plasma membrane and into the cytosol.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0036153	biolink:NamedThing	triglyceride acyl-chain remodeling	Remodeling the acyl chains of triacylglycerol, through sequential deacylation and re-acylation reactions, to generate triacylglycerol containing different types of fatty acid acyl chains.	tmpzr1t_l9r_go_relaxed.owl	triacylglycerol acyl-chain remodeling							bf	2012-03-14T02:49:05Z					biological_process											owl:Class	
GO:0051161	biolink:NamedThing	arabitol metabolic process	The chemical reactions and pathways involving arabitol, the pentitol derived from arabinose or lyxose by reduction of the aldehyde group.	tmpzr1t_l9r_go_relaxed.owl	arabitol metabolism													biological_process											owl:Class	
GO:0036531	biolink:NamedThing	glutathione deglycation	The removal of a sugar or dicarbonyl from glycated glutathione. Glutathione is the tripeptide glutamylcysteinylglycine.	tmpzr1t_l9r_go_relaxed.owl								bf	2016-08-04T10:45:27Z					biological_process											owl:Class	
GO:0042636	biolink:NamedThing	negative regulation of hair cycle	Any process that stops, prevents, or reduces the frequency, rate or extent of the cyclical phases of growth (anagen), regression (catagen), quiescence (telogen), and shedding (exogen) in the life of a hair.	tmpzr1t_l9r_go_relaxed.owl	inhibition of hair cycle|down-regulation of hair cycle|down regulation of hair cycle|downregulation of hair cycle													biological_process											owl:Class	
GO:0007366	biolink:NamedThing	periodic partitioning by pair rule gene	Allocation of cells to parasegments in the embryo, through the action of overlapping series of pair rule gene activities.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0007365	biolink:NamedThing	periodic partitioning	The regionalization process that divides the spatial regions of an embryo into serially repeated regions.	tmpzr1t_l9r_go_relaxed.owl						Note that examples of periodic partitions are tagmata, segments or parasegments.								biological_process											owl:Class	
GO:0010895	biolink:NamedThing	negative regulation of ergosterol biosynthetic process	Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of ergosterol.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0106119	biolink:NamedThing	negative regulation of sterol biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of a sterol biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl								hjd	2018-04-19T17:44:46Z					biological_process											owl:Class	
GO:0075047	biolink:NamedThing	negative regulation of formation by symbiont of haustorium for nutrient acquisition from host	Any process that stops, prevents, or reduces the frequency, rate or extent of symbiont haustorium formation for nutrient acquisition from host. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl						Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products from the symbiont involved in this process.								biological_process											owl:Class	
GO:0009970	biolink:NamedThing	cellular response to sulfate starvation	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of sulfate.	tmpzr1t_l9r_go_relaxed.owl	cellular response to sulphate starvation													biological_process											owl:Class	
GO:0018899	biolink:NamedThing	1,2-dichloroethane metabolic process	The chemical reactions and pathways involving 1,2-dichloroethane, a major commodity chemical used, for example, in the manufacture of vinyl chloride.	tmpzr1t_l9r_go_relaxed.owl	1,2-dichloroethane metabolism				UM-BBD_pathwayID:dce									biological_process											owl:Class	
GO:2001211	biolink:NamedThing	negative regulation of isopentenyl diphosphate biosynthetic process, mevalonate pathway	Any process that stops, prevents or reduces the frequency, rate or extent of isopentenyl diphosphate biosynthetic process, mevalonate pathway.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of Ac-MVA pathway|negative regulation of isopentenyl diphosphate formation, mevalonate pathway|negative regulation of isopentenyl diphosphate synthesis, mevalonate pathway|negative regulation of isopentenyl diphosphate anabolism, mevalonate pathway|negative regulation of acetate-mevalonate pathway							bf	2011-11-15T10:53:45Z					biological_process											owl:Class	
GO:0000969	biolink:NamedThing	tRNA exon ligation utilizing ATP as source of linkage phosphate	A tRNA exon ligation process in which the splice junction phosphate is derived from exogenous ATP. This type of ligation to rejoin the 5' and 3' exons of a tRNA is observed in vertebrate species.	tmpzr1t_l9r_go_relaxed.owl								krc	2009-04-28T10:29:37Z					biological_process											owl:Class	
GO:0008877	biolink:NamedThing	glucose-1-phosphatase activity	Catalysis of the reaction: alpha-D-glucose 1-phosphate + H2O = D-glucose + phosphate.	tmpzr1t_l9r_go_relaxed.owl	alpha-D-glucose-1-phosphate phosphohydrolase activity|D-glucose-1-phosphate phosphohydrolase activity				EC:3.1.3.10|MetaCyc:GLUCOSE-1-PHOSPHAT-RXN|KEGG_REACTION:R00304|RHEA:19933									molecular_function											owl:Class	
GO:0090032	biolink:NamedThing	negative regulation of steroid hormone biosynthetic process	Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroid hormones,compounds with a 1, 2, cyclopentanoperhydrophenanthrene nucleus that act as hormones.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-08-03T10:41:35Z					biological_process											owl:Class	
GO:0008676	biolink:NamedThing	3-deoxy-8-phosphooctulonate synthase activity	Catalysis of the reaction: D-arabinose 5-phosphate + H(2)O + phosphoenolpyruvate = 8-phospho-3-deoxy-D-manno-oct-2-ulosonate + 2 H(+) + phosphate.	tmpzr1t_l9r_go_relaxed.owl	2-keto-3-deoxy-8-phosphooctonic synthetase activity|2-dehydro-3-deoxy-phosphooctonate aldolase activity|2-dehydro-3-deoxyphosphooctonate aldolase activity|phospho-2-keto-3-deoxyoctonate aldolase activity|phosphoenolpyruvate:D-arabinose-5-phosphate C-(1-carboxyvinyl)transferase (phosphate-hydrolysing, 2-carboxy-2-oxoethyl-forming)|3-deoxy-D-manno-octulosonic acid 8-phosphate synthetase activity|2-dehydro-3-deoxy-D-octonate-8-phosphate D-arabinose-5-phosphate-lyase (pyruvate-phosphorylating) activity|3-deoxyoctulosonic 8-phosphate synthetase activity|3-deoxy-D-manno-octulosonate-8-phosphate synthase activity|3-deoxy-D-mannooctulosonate-8-phosphate synthetase activity|KDO-8-phosphate synthetase activity|KDO-8-P synthase activity|KDOP synthase activity				RHEA:14053|EC:2.5.1.55|MetaCyc:KDO-8PSYNTH-RXN|KEGG_REACTION:R03254	Note that this function was formerly EC:4.1.2.16.								molecular_function											owl:Class	
GO:0036526	biolink:NamedThing	peptidyl-cysteine deglycation	The removal of a sugar or dicarbonyl from a cysteine residue of a glycated protein.	tmpzr1t_l9r_go_relaxed.owl	deglycation of N-acetylcysteine							bf	2016-08-04T10:35:25Z					biological_process											owl:Class	
GO:0010096	biolink:NamedThing	specification of sepal identity	The process in which a floral organ primordium acquires sepal identity. Identity is considered to be the aggregate of characteristics by which a structure is recognized.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0006239	biolink:NamedThing	dCMP salvage	Any process that generates dCMP, deoxycytidine monophosphate from derivatives of it, without de novo synthesis.	tmpzr1t_l9r_go_relaxed.owl	deoxycytidine monophosphate salvage													biological_process											owl:Class	
GO:0097259	biolink:NamedThing	20-aldehyde-leukotriene B4 20-monooxygenase activity	Catalysis of the reaction: 20-oxo-leukotriene B4 + O2 + reduced [NADPH-hemoprotein reductase] = 20-carboxy-leukotriene B4 + 2 H+ + H2O + oxidized [NADPH-hemoprotein reductase].	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-2161792|Reactome:R-HSA-2161979|RHEA:48672			pr	2012-03-07T03:40:05Z					molecular_function											owl:Class	
GO:0051703	biolink:NamedThing	biological process involved in intraspecies interaction between organisms	Any process in which an organism has an effect on an organism of the same species.	tmpzr1t_l9r_go_relaxed.owl	intraspecies interaction between organisms|intraspecies interaction with other organisms	https://github.com/geneontology/go-ontology/issues/20191												biological_process											owl:Class	
GO:0070395	biolink:NamedThing	lipoteichoic acid biosynthetic process	The chemical reactions and pathways resulting in the formation of lipoteichoic acid, which is a major component of the cell wall of gram-positive bacteria and typically consists of a chain of glycerol-phosphate repeating units linked to a glycolipid anchor.	tmpzr1t_l9r_go_relaxed.owl	lipoteichoic acid synthesis|lipoteichoic acid anabolism|lipoteichoic acid formation|lipoteichoic acid biosynthesis|LTA biosynthetic process													biological_process											owl:Class	
GO:0071836	biolink:NamedThing	nectar secretion	The controlled release of a nectar by a cell or a tissue. Nectar is a fluid secreted by many angiosperms to promote pollination by providing a reward to pollinators. Nectar may also deter certain organisms from visiting or play other biological roles. Nectar is a complex solution that may include the following types of compounds: sugars, amino acids, organic acids, alkaloids, flavonoids, glycosides, vitamins, phenolics, metal ions, oils, free fatty acids, and proteins.	tmpzr1t_l9r_go_relaxed.owl	nectar production							mah	2010-09-09T01:06:04Z					biological_process											owl:Class	
GO:0060425	biolink:NamedThing	lung morphogenesis	The process in which the anatomical structures of the lung are generated and organized.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0001515	biolink:NamedThing	opioid peptide activity	Naturally occurring peptide that is an opioid (any non-alkaloid having an opiate-like effect that can be reversed by naloxone or other recognized morphine antagonist). These include Leu- and Met-enkephalin, dynorphin and neoendorphin, alpha, beta, gamma and delta endorphins formed from beta-lipotropin, various pronase-resistant peptides such as beta casamorphin, and other peptides whose opiate-like action seems to be indirect.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0033675	biolink:NamedThing	pericanalicular vesicle	A membrane-bounded vesicle found near the apical, or pericanalicular, membrane of a hepatocyte; contains proteins involved in bile salt transport and other fluid and solute transport processes.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0098806	biolink:NamedThing	mRNA deadenylation-mediated gene silencing by miRNA	Shortening of the poly(A) tail of a nuclear-transcribed mRNA following miRNA binding to mRNA, resulting in destabilization of the mRNA and a reduction in the efficiency of its translation.	tmpzr1t_l9r_go_relaxed.owl	deadenylation involved in gene silencing by miRNA	https://github.com/geneontology/go-ontology/issues/20568												biological_process											owl:Class	
GO:0035279	biolink:NamedThing	mRNA destabilization-mediated gene silencing by miRNA	The process in which microRNAs (miRNAs) direct the cleavage of target mRNAs. Once incorporated into a RNA-induced silencing complex (RISC), a miRNA base pairing with near-perfect complementarity to the target mRNA will typically direct targeted endonucleolytic cleavage of the mRNA. Many plant miRNAs downregulate gene expression through this mechanism.	tmpzr1t_l9r_go_relaxed.owl	mRNA cleavage involved in gene silencing by microRNA|mRNA cleavage involved in gene silencing by miRNA|gene silencing by miRNA, mRNA cleavage|miRNA-mediated gene silencing, mRNA cleavage	https://github.com/geneontology/go-ontology/issues/22389												biological_process											owl:Class	
GO:0018296	biolink:NamedThing	protein-FAD linkage via O4'-(8alpha-FAD)-L-tyrosine	The formation of a protein-FAD linkage via O4'-(8-alpha-FAD)-L-tyrosine.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0145									biological_process											owl:Class	
GO:2000265	biolink:NamedThing	positive regulation of blood coagulation, extrinsic pathway	Any process that activates or increases the frequency, rate or extent of blood coagulation, extrinsic pathway.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-11-23T11:44:46Z					biological_process											owl:Class	
GO:0002942	biolink:NamedThing	tRNA m2,2-guanine biosynthesis	The process whereby a guanine residue in a transfer RNA is methylated twice at the N2 position.	tmpzr1t_l9r_go_relaxed.owl								hjd	2012-11-16T16:07:20Z					biological_process											owl:Class	
GO:1905119	biolink:NamedThing	response to haloperidol	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a haloperidol stimulus.	tmpzr1t_l9r_go_relaxed.owl						Note that this term is in the subset of terms that should not be used for direct manual annotation of gene products. It was created to be used for cross-referencing by other ontologies. Direct annotations to this term may be amended during annotation QC.		dw	2016-04-08T12:36:39Z					biological_process											owl:Class	
GO:0043924	biolink:NamedThing	suramin binding	Binding to suramin, a naphthalenesulfonic acid compound which is used in the treatment of diseases caused by trypanosomes and worms.	tmpzr1t_l9r_go_relaxed.owl	Germanin binding													molecular_function											owl:Class	
GO:0035457	biolink:NamedThing	cellular response to interferon-alpha	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-alpha stimulus. Interferon-alpha is a type I interferon.	tmpzr1t_l9r_go_relaxed.owl	cellular response to interferon alfa-n3|cellular response to lymphoblastoid interferon|cellular response to lymphoblast interferon|cellular response to interferon alfa-n1|cellular response to leukocyte interferon							bf	2010-04-16T11:08:29Z					biological_process											owl:Class	
GO:0046381	biolink:NamedThing	CMP-N-acetylneuraminate metabolic process	The chemical reactions and pathways involving CMP-N-acetylneuraminate, a substance composed of 5-(acetylamino)-3,5-dideoxy-D-glycero-D-galacto-non-3-ulosonic acid in glycosidic linkage with cytidine monophosphate.	tmpzr1t_l9r_go_relaxed.owl	CMP-N-acetylneuraminate metabolism													biological_process											owl:Class	
GO:0044875	biolink:NamedThing	gamma-glutamyl hercynylcysteine sulfoxide synthase activity	Catalysis of the reaction: gamma-glutamyl cysteine + hercynine + O2 <=> gamma-glutamyl-hercynyl cysteine sulfoxide + H2O.	tmpzr1t_l9r_go_relaxed.owl	gamma-glutamyl hercynylcysteine S-oxide synthase|gamma-glutamyl hercynylcysteine sulfoxide synthase	https://github.com/geneontology/go-ontology/issues/11163			EC:1.14.99.50|RHEA:42672			jl	2014-12-15T11:44:54Z					molecular_function											owl:Class	
GO:0032445	biolink:NamedThing	fructose import	The directed movement of the hexose monosaccharide fructose into a cell or organelle.	tmpzr1t_l9r_go_relaxed.owl	fructose uptake													biological_process											owl:Class	
GO:0008876	biolink:NamedThing	quinoprotein glucose dehydrogenase activity	Catalysis of the reaction: D-glucose + ubiquinone = D-glucono-1,5-lactone + ubiquinol.	tmpzr1t_l9r_go_relaxed.owl	glucose dehydrogenase (pyrroloquinoline-quinone) activity|quinoprotein D-glucose dehydrogenase activity|glucose dehydrogenase (PQQ-dependent) activity|D-glucose:(pyrroloquinoline-quinone) 1-oxidoreductase activity|D-glucose:ubiquinone oxidoreductase activity				EC:1.1.5.2|RHEA:22152|MetaCyc:GLUCDEHYDROG-RXN	Formerly EC:1.1.99.17.								molecular_function											owl:Class	
GO:0004344	biolink:NamedThing	glucose dehydrogenase activity	Catalysis of the reaction: D-glucose + acceptor = D-glucono-1,5-lactone + reduced acceptor.	tmpzr1t_l9r_go_relaxed.owl	glucose dehydrogenase (Aspergillus) activity|D-glucose:acceptor 1-oxidoreductase|glucose dehydrogenase (acceptor) activity|glucose dehydrogenase (decarboxylating)|D-glucose:(acceptor) 1-oxidoreductase				MetaCyc:GLUCOSE-DEHYDROGENASE-ACCEPTOR-RXN|EC:1.1.99.10|KEGG_REACTION:R00305|RHEA:24540							GO:0008708		molecular_function											owl:Class	
GO:0033918	biolink:NamedThing	kappa-carrageenase activity	Catalysis of the endohydrolysis of 1,4-beta-D-linkages between D-galactose 4-sulfate and 3,6-anhydro-D-galactose in kappa-carrageenans.	tmpzr1t_l9r_go_relaxed.owl	kappa-carrageenan 4-beta-D-glycanohydrolase (configuration-retaining) activity|kappa-carrageenan 4-beta-D-glycanohydrolase activity				MetaCyc:3.2.1.83-RXN|EC:3.2.1.83									molecular_function											owl:Class	
GO:0018886	biolink:NamedThing	anaerobic carbon tetrachloride metabolic process	The chemical reactions and pathways involving carbon tetrachloride, a toxic, carcinogenic compound which is used as a general solvent in industrial degreasing operations, that occur in the absence of oxygen.	tmpzr1t_l9r_go_relaxed.owl	anaerobic carbon tetrachloride metabolism				UM-BBD_pathwayID:ctc									biological_process											owl:Class	
GO:0003412	biolink:NamedThing	establishment of epithelial cell apical/basal polarity involved in camera-type eye morphogenesis	The specification and formation of the apicobasal polarity of an epithelial cell that contributes to the shaping of a camera-type eye.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-12-21T03:09:23Z					biological_process											owl:Class	
GO:0005167	biolink:NamedThing	neurotrophin TRK receptor binding	Binding to a neurotrophin TRK receptor.	tmpzr1t_l9r_go_relaxed.owl	neurotrophin TRK receptor ligand													molecular_function											owl:Class	
GO:0071628	biolink:NamedThing	intrinsic component of fungal-type vacuolar membrane	The component of a fungal-type vacuole membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-02-10T03:53:00Z					cellular_component											owl:Class	
GO:0036309	biolink:NamedThing	protein localization to M-band	Any process in which a protein is transported to, and/or maintained in, the M band. The M band is the midline of aligned thick filaments in a sarcomere.	tmpzr1t_l9r_go_relaxed.owl	protein localization to mesophragma|protein localization to M disc|cellular protein localization to M-band|protein localization to M line							bf	2012-08-14T14:02:58Z					biological_process											owl:Class	
GO:1905473	biolink:NamedThing	positive regulation of histone H3-K79 dimethylation	Any process that activates or increases the frequency, rate or extent of histone H3-K79 dimethylation.	tmpzr1t_l9r_go_relaxed.owl	up regulation of histone H3-K79 dimethylation|up regulation of histone H3 K79 dimethylation|upregulation of histone H3 K79 dimethylation|positive regulation of histone lysine H3 K79 dimethylation|activation of histone H3-K79 dimethylation|up-regulation of histone H3 K79 dimethylation|up-regulation of histone lysine H3 K79 dimethylation|up regulation of histone lysine H3 K79 dimethylation|positive regulation of histone H3 K79 dimethylation|up-regulation of histone H3-K79 dimethylation|activation of histone lysine H3 K79 dimethylation|upregulation of histone H3-K79 dimethylation|activation of histone H3 K79 dimethylation|upregulation of histone lysine H3 K79 dimethylation							hbye	2016-09-21T15:27:17Z					biological_process											owl:Class	
GO:0050257	biolink:NamedThing	riboflavin phosphotransferase activity	Catalysis of the reaction: alpha-D-glucose 1-phosphate + riboflavin = D-glucose + FMN.	tmpzr1t_l9r_go_relaxed.owl	G-1-P phosphotransferase activity|D-glucose-1-phosphate:riboflavin 5'-phosphotransferase activity|riboflavine phosphotransferase activity|alpha-D-glucose-1-phosphate:riboflavin 5'-phosphotransferase activity				KEGG_REACTION:R00550|MetaCyc:RIBOFLAVIN-PHOSPHOTRANSFERASE-RXN|RHEA:20409|EC:2.7.1.42									molecular_function											owl:Class	
GO:0015819	biolink:NamedThing	lysine transport	The directed movement of lysine, 2,6-diaminohexanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	L-lysine import|lysine import|lysine uptake|L-lysine transport							dph	2012-10-05T10:22:26Z			GO:0034226|GO:0061461		biological_process											owl:Class	
GO:0015802	biolink:NamedThing	basic amino acid transport	The directed movement of basic amino acids, amino acids with a pH above 7, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0050911	biolink:NamedThing	detection of chemical stimulus involved in sensory perception of smell	The series of events involved in the perception of smell in which an olfactory chemical stimulus is received and converted into a molecular signal.	tmpzr1t_l9r_go_relaxed.owl	perception of smell, sensory transduction of chemical stimulus|sensory detection of smell|sensory transduction of chemical stimulus during perception of smell|perception of smell, detection of chemical stimulus|sensory detection of scent|sensory detection of chemical stimulus during perception of smell|perception of smell, sensory detection of chemical stimulus|sensory transduction of scent|sensory transduction of smell													biological_process											owl:Class	
GO:0034751	biolink:NamedThing	aryl hydrocarbon receptor complex	A protein complex that acts as an aryl hydrocarbon (Ah) receptor. Cytosolic and nuclear Ah receptor complexes have different subunit composition, but both contain the ligand-binding subunit AhR.	tmpzr1t_l9r_go_relaxed.owl	AHRC|AhR complex													cellular_component											owl:Class	
GO:1902058	biolink:NamedThing	regulation of sporocarp development involved in sexual reproduction	Any process that modulates the frequency, rate or extent of sporocarp development involved in sexual reproduction.	tmpzr1t_l9r_go_relaxed.owl	regulation of perfect stage fruiting body development|regulation of fruiting body development involved in sexual reproduction|regulation of ascus development|regulation of fruiting body formation involved in sexual reproduction							di	2013-04-16T04:08:38Z					biological_process											owl:Class	
GO:0009865	biolink:NamedThing	pollen tube adhesion	The process in which the pollen tube adheres to cells of the stigma and style.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0004873	biolink:NamedThing	asialoglycoprotein receptor activity	Receiving an asialoglycoprotein, and delivering the asialoglycoprotein into the cell via endocytosis. An asialoglycoprotein is a plasma glycoproteins from which the terminal sialic acid residue on their complex carbohydrate groups has been removed. The asialoglycoprotein receptor recognizes the terminal galactose and N-acetylgalactosamine units of the asialoglycoprotein, the receptor-ligand complex is internalized and transported to a sorting organelle where disassociation occurs before the receptor is recycled to the cell membrane.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0050289	biolink:NamedThing	spermidine dehydrogenase activity	Catalysis of the reaction: spermidine + acceptor + H2O = 1,3-diaminopropane + 4-aminobutanal + reduced acceptor.	tmpzr1t_l9r_go_relaxed.owl	spermidine:(acceptor) oxidoreductase activity|spermidine:acceptor oxidoreductase activity				RHEA:14273|EC:1.5.99.6|MetaCyc:SPERMIDINE-DEHYDROGENASE-RXN									molecular_function											owl:Class	
GO:0047758	biolink:NamedThing	ATP:2-methylpropanoate phosphotransferase activity	Catalysis of the reaction: 2-methylpropanoate + ATP = 2-methylpropanoyl phosphate + ADP + H(+).	tmpzr1t_l9r_go_relaxed.owl	ATP:isobutyrate 1-phosphotransferase activity|isobutyrate kinase activity|ATP:2-methylpropanoate 1-phosphotransferase activity|branched-chain-fatty-acid kinase activity|ATP:branched-chain-fatty-acid 1-phosphotransferase activity|branched-chain fatty acid kinase activity|ATP:2-methylpropanoate kinase activity				MetaCyc:BRANCHED-CHAIN-FATTY-ACID-KINASE-RXN|EC:2.7.2.14|KEGG_REACTION:R04002|RHEA:24156									molecular_function											owl:Class	
GO:0150016	biolink:NamedThing	basal distal dendrite	Any dendrite in a dendritic tree that emerges near the basal pole of a neuron (e.g. in bipolar neurons, basal dendrites are either on the same side of the soma as the axon, or project toward the axon), and which is farthest away from the neuronal cell body (the soma).	tmpzr1t_l9r_go_relaxed.owl								bc	2017-12-21T12:11:47Z					cellular_component											owl:Class	
GO:1901595	biolink:NamedThing	response to hesperadin	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hesperadin stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2012-11-07T17:16:57Z					biological_process											owl:Class	
GO:0061607	biolink:NamedThing	peptide alpha-N-propionyltransferase activity	Catalysis of the reaction: propionyl-CoA + peptide = CoA + N-alpha-propionylpeptide. This reaction is the propionylation of the N-terminal amino acid residue of a peptide or protein.	tmpzr1t_l9r_go_relaxed.owl	N-terminal propionyltransferase activity							dph	2014-02-11T14:24:35Z					molecular_function											owl:Class	
GO:0036110	biolink:NamedThing	cellular response to inositol starvation	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of inositol.	tmpzr1t_l9r_go_relaxed.owl								bf	2012-02-15T10:46:07Z					biological_process											owl:Class	
GO:2000751	biolink:NamedThing	histone H3-T3 phosphorylation involved in chromosome passenger complex localization to kinetochore	Any histone H3-T3 phosphorylation that is involved in chromosome passenger complex localization to kinetochore.	tmpzr1t_l9r_go_relaxed.owl	histone H3-T3 phosphorylation of chromosome passenger complex localization to kinetochore|histone H3-T3 phosphorylation of chromosomal passenger complex localization to kinetochore|histone H3-T3 phosphorylation of CPC localization to kinetochore|histone H3-T3 phosphorylation of CPC complex localization to kinetochore|histone H3-T3 phosphorylation of chromosome passenger complex localisation to kinetochore							vw	2011-06-16T12:56:29Z					biological_process											owl:Class	
GO:0035357	biolink:NamedThing	peroxisome proliferator activated receptor signaling pathway	The series of molecular signals initiated by binding of a ligand to any of the peroxisome proliferator activated receptors (alpha, beta or gamma) in the nuclear membrane, and ending with the initiation or termination of the transcription of target genes.	tmpzr1t_l9r_go_relaxed.owl	PPAR signaling pathway|peroxisome proliferator activated receptor signalling pathway|peroxisome proliferator-activated receptor signaling pathway							bf	2010-03-05T10:30:10Z					biological_process											owl:Class	
GO:1905664	biolink:NamedThing	regulation of calcium ion import across plasma membrane	Any process that modulates the frequency, rate or extent of calcium ion import across plasma membrane.	tmpzr1t_l9r_go_relaxed.owl						An example of this is PPP3CA in human (Q08209) in 17640527 (inferred from direct assay).		bhm	2016-11-11T09:26:06Z					biological_process											owl:Class	
GO:0071181	biolink:NamedThing	MAML3-RBP-Jkappa-ICN3 complex	A protein complex that consists of the intracellular domain of Notch3 (ICN3), the DNA-binding transcription factor RBP-Jkappa, and the transcriptional coactivator Mastermind-like-3 (MAML3); the complex is involved in transcriptional activation in response to Notch-mediated signaling.	tmpzr1t_l9r_go_relaxed.owl	MAML3-RBP-Jkappa-Notch3 complex							mah	2009-11-23T02:52:05Z					cellular_component											owl:Class	
GO:1905628	biolink:NamedThing	negative regulation of serotonin biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of serotonin biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	down regulation of serotonin biosynthesis|inhibition of serotonin biosynthetic process|inhibition of serotonin synthesis|downregulation of serotonin anabolism|down-regulation of serotonin anabolism|inhibition of serotonin formation|down-regulation of serotonin synthesis|inhibition of serotonin biosynthesis|down regulation of serotonin formation|downregulation of serotonin synthesis|negative regulation of serotonin biosynthesis|down regulation of serotonin anabolism|down-regulation of serotonin formation|down-regulation of serotonin biosynthetic process|down-regulation of serotonin biosynthesis|downregulation of serotonin formation|downregulation of serotonin biosynthesis|inhibition of serotonin anabolism|downregulation of serotonin biosynthetic process|down regulation of serotonin synthesis|negative regulation of serotonin formation|negative regulation of serotonin anabolism|negative regulation of serotonin synthesis|down regulation of serotonin biosynthetic process							pad	2016-10-31T14:26:28Z					biological_process											owl:Class	
GO:0047894	biolink:NamedThing	flavonol 3-sulfotransferase activity	Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + quercetin = adenosine 3',5'-diphosphate + H(+) + quercetin 3-sulfate.	tmpzr1t_l9r_go_relaxed.owl	3'-phosphoadenylyl-sulfate:quercetin 3-sulfotransferase activity|flavonol 3-sulphotransferase activity				RHEA:13453|EC:2.8.2.25|KEGG_REACTION:R02159|MetaCyc:FLAVONOL-3-SULFOTRANSFERASE-RXN									molecular_function											owl:Class	
GO:0043427	biolink:NamedThing	carbon fixation by 3-hydroxypropionate cycle	An autotrophic carbon dioxide fixation pathway by which two molecules of carbon dioxide are fixed to form glyoxylate. Acetyl coenzyme A (acetyl-CoA) is assumed to be converted to malate, and two CO2 molecules are thereby fixed. Malyl-CoA is thought to be cleaved to acetyl-CoA, the starting molecule, and glyoxylate, the carbon fixation product.	tmpzr1t_l9r_go_relaxed.owl	hydroxypropionate cycle|hydroxypropionate pathway|3-hydroxypropionate cycle|3-hydroxypropionate pathway													biological_process											owl:Class	
GO:0036290	biolink:NamedThing	protein trans-autophosphorylation	The phosphorylation by a protein of a residue on an identical protein. For example, phosphorylation by the other kinase within a homodimer.	tmpzr1t_l9r_go_relaxed.owl	trans-autophosphorylation							bf	2012-07-18T10:27:06Z					biological_process											owl:Class	
GO:0034831	biolink:NamedThing	(R)-(-)-1,2,3,4-tetrahydronaphthol dehydrogenase activity	Catalysis of the reaction: (R)-1,2,3,4-tetrahydronaphthol = 1,2,3,4-tetrahydronaphthalone + 2 H+ + 2 e-.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r1176									molecular_function											owl:Class	
GO:1904050	biolink:NamedThing	positive regulation of spontaneous neurotransmitter secretion	Any process that activates or increases the frequency, rate or extent of spontaneous neurotransmitter secretion.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of stimulus-independent neurotransmitter secretion|up regulation of spontaneous neurotransmitter secretion|upregulation of spontaneous neurotransmitter secretion|activation of stimulus-independent neurotransmitter secretion|activation of spontaneous neurotransmitter secretion|up regulation of stimulus-independent neurotransmitter secretion|up-regulation of spontaneous neurotransmitter secretion|upregulation of stimulus-independent neurotransmitter secretion|positive regulation of stimulus-independent neurotransmitter secretion					An example of this is PARK2 / parkin in human (O60260) in PMID:22314364 (inferred from mutant phenotype).		pad	2015-03-17T10:37:23Z					biological_process											owl:Class	
GO:1900167	biolink:NamedThing	negative regulation of glial cell-derived neurotrophic factor production	Any process that stops, prevents or reduces the frequency, rate or extent of glial cell-derived neurotrophic factor production.	tmpzr1t_l9r_go_relaxed.owl	inhibition of glial cell line-derived neurotrophic factor secretion|negative regulation of glial cell-derived neurotrophic factor secretion|negative regulation of GDNF secretion|inhibition of GDNF secretion|negative regulation of glial cell line-derived neurotrophic factor secretion							yaf	2012-03-08T03:44:43Z					biological_process											owl:Class	
GO:2000696	biolink:NamedThing	regulation of epithelial cell differentiation involved in kidney development	Any process that modulates the frequency, rate or extent of epithelial cell differentiation involved in kidney development.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-05-16T04:23:52Z					biological_process											owl:Class	
GO:0014832	biolink:NamedThing	urinary bladder smooth muscle contraction	A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the urinary bladder. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The urinary bladder is a musculomembranous sac along the urinary tract.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1904475	biolink:NamedThing	regulation of small GTPase binding	Any process that modulates the frequency, rate or extent of small GTPase binding.	tmpzr1t_l9r_go_relaxed.owl	regulation of Ras GTPase binding	https://github.com/geneontology/go-ontology/issues/18750						sl	2015-07-10T22:47:31Z					biological_process											owl:Class	
GO:0016994	biolink:NamedThing	precorrin-6A reductase activity	Catalysis of the reaction: precorrin-6B + NADP+ = precorrin-6A + NADPH + H+.	tmpzr1t_l9r_go_relaxed.owl	precorrin-6B:NADP+ oxidoreductase activity|precorrin-6Y:NADP+ oxidoreductase activity|precorrin-6Y:NADP(+) oxidoreductase activity|precorrin-6X reductase activity				EC:1.3.1.54|MetaCyc:1.3.1.54-RXN|RHEA:23408									molecular_function											owl:Class	
GO:0019084	biolink:NamedThing	middle viral transcription	The viral transcription that takes place after early transcription in the viral life cycle, and which involves the transcription of genes required for replication.	tmpzr1t_l9r_go_relaxed.owl	(delayed) early viral mRNA transcription													biological_process											owl:Class	
GO:0031617	biolink:NamedThing	NMS complex	A supercomplex formed by the association of two subcomplexes (known as MIND and Ndc80 in Schizosaccharomyces) with additional proteins at the kinetochores of condensed nuclear chromosomes.	tmpzr1t_l9r_go_relaxed.owl	KMN kinetochore network|Ndc80-MIND-Spc7 complex|KNL-1-Mis12-Ndc80													cellular_component											owl:Class	
GO:0044551	biolink:NamedThing	envenomation resulting in vasodilation in other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with resultant vasodilation of blood vessels, usually causing a reduction in blood pressure, in the bitten/stung organism.	tmpzr1t_l9r_go_relaxed.owl	envenomation resulting in modulation of vasodilation in other organism|envenomation resulting in regulation of vasodilation in other organism							jl	2012-03-29T02:07:45Z					biological_process											owl:Class	
GO:0140646	biolink:NamedThing	negative regulation of pre-B cell receptor expression	Any process that stops, prevents or reduces the frequency, rate or extent of the process leading up to expression of the pre-B cell receptor on the surface of pre-B cells.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/20121						pg	2021-05-19T10:50:53Z					biological_process											owl:Class	
GO:0075511	biolink:NamedThing	macropinosome lysis involved in viral entry into host cell	Viral-induced lysis of the macropinosome involved in the uptake of a virus into a host cell. Occurs after internalization of the virus in a macropinosome, and results in the release of viral contents from the macropinosome into the host cell cytoplasm.	tmpzr1t_l9r_go_relaxed.owl								jl	2011-07-27T11:38:07Z					biological_process											owl:Class	
GO:0034159	biolink:NamedThing	regulation of toll-like receptor 8 signaling pathway	Any process that modulates the frequency, rate, or extent of toll-like receptor 8 signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	regulation of TLR8 signaling pathway|regulation of toll-like receptor 8 signalling pathway													biological_process											owl:Class	
GO:0019929	biolink:NamedThing	peptide cross-linking via 4-(S-L-cysteinyl)-L-glutamic acid	The cross-linking of a cysteine residue to a glutamic acid residue to form 4-(S-L-cysteinyl)-L-glutamic acid.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0315									biological_process											owl:Class	
GO:0071164	biolink:NamedThing	RNA trimethylguanosine synthase activity	Catalysis of two successive methyl transfer reactions from AdoMet to the N-2 atom of guanosine, thereby converting 7-methylguanosine in an RNA cap to 2,2,7 trimethylguanosine.	tmpzr1t_l9r_go_relaxed.owl	snRNA methyltransferase activity|cap hypermethylase activity|small nuclear RNA methyltransferase activity							mah	2009-11-19T03:23:20Z					molecular_function											owl:Class	
GO:0052163	biolink:NamedThing	symbiont defense to host-produced nitric oxide	Any process in which a symbiont modulates the frequency, rate or extent of the production of nitric oxide as part of the innate immune response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	modulation by organism of defense-related host NO production|evasion or tolerance by organism of nitric oxide produced by other organism involved in symbiotic interaction|response to defense-related host nitric oxide production|modulation by organism of defense-related nitric oxide production in other organism involved in symbiotic interaction|defense response to host innate immune response nitric oxide production|evasion or tolerance by organism of host-produced nitric oxide|evasion or tolerance by organism of host-produced NO|response to defense-related nitric oxide production by other organism involved in symbiotic interaction|evasion or tolerance of nitric oxide produced by host in response to organism|evasion or tolerance by organism of host nitric oxide|evasion or tolerance by symbiont of host-produced nitric oxide|modulation by symbiont of defense-related host nitric oxide production|evasion or tolerance by organism of host NO|evasion or tolerance of NO produced by host in response to organism	https://github.com/geneontology/go-ontology/issues/18798										GO:0052565|GO:0052376|GO:0052551|GO:0052060|GO:0052302		biological_process											owl:Class	
GO:0044641	biolink:NamedThing	envenomation resulting in positive regulation of complement activation, lectin pathway in other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant positive regulation of complement activation via the lectin pathway in the bitten/stung organism.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-07-11T11:50:23Z					biological_process											owl:Class	
GO:0010724	biolink:NamedThing	regulation of definitive erythrocyte differentiation	Any process that modulates the rate, frequency, or extent of definitive erythrocyte differentiation. Definitive erythrocyte differentiation occurs as part of the process of definitive hemopoiesis.	tmpzr1t_l9r_go_relaxed.owl	regulation of definitive erythropoiesis|regulation of definitive RBC differentiation|regulation of definitive red blood cell differentiation													biological_process											owl:Class	
GO:1903621	biolink:NamedThing	protein localization to photoreceptor connecting cilium	A process in which a protein is transported to, or maintained in, a location within a photoreceptor connecting cilium.	tmpzr1t_l9r_go_relaxed.owl	protein localisation in photoreceptor connecting cilium|protein localisation to photoreceptor connecting cilium|protein localization in photoreceptor connecting cilium							jl	2014-11-19T17:17:17Z					biological_process											owl:Class	
GO:1904491	biolink:NamedThing	protein localization to ciliary transition zone	A process in which a protein is transported to, or maintained in, a location within a ciliary transition zone.	tmpzr1t_l9r_go_relaxed.owl	protein localisation to ciliary transition zone|protein localisation in ciliary transition zone|protein localization in ciliary transition zone							kmv	2015-07-17T20:43:21Z					biological_process											owl:Class	
GO:2000882	biolink:NamedThing	negative regulation of starch catabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of starch catabolic process.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of starch catabolism|negative regulation of starch degradation|negative regulation of starch breakdown							bf	2011-07-27T03:23:46Z					biological_process											owl:Class	
GO:0052867	biolink:NamedThing	phosphatidylinositol-1,4,5-trisphosphate 5-phosphatase activity	Catalysis of the reaction: phosphatidyl-1D-myo-inositol 1,4,5-trisphosphate + H(2)O = 1-phosphatidyl-1D-myo-inositol 1,4-bisphosphate + phosphate.	tmpzr1t_l9r_go_relaxed.owl	phosphatidylinositol-trisphosphatase activity|PtdIns(1,4,5)P3 phosphatase activity|phosphatidyl-myo-inositol-1,4,5-trisphosphate phosphatase activity|triphosphoinositide phosphatase activity|PtdIns(1,4,5)P(3) phosphatase activity|triphosphoinositide phosphomonoesterase activity|phosphatidylinositol 1,4,5-trisphosphate phosphatase activity								2012-01-11T12:07:50Z					molecular_function											owl:Class	
GO:0034594	biolink:NamedThing	phosphatidylinositol trisphosphate phosphatase activity	Catalysis of the reaction: phosphatidylinositol trisphosphate + H2O = phosphatidylinositol bisphosphate + phosphate.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1901027	biolink:NamedThing	dextrin catabolic process	The chemical reactions and pathways resulting in the breakdown of dextrin.	tmpzr1t_l9r_go_relaxed.owl	dextrin degradation|dextrin catabolism|dextrin breakdown							al	2012-06-19T03:12:19Z					biological_process											owl:Class	
GO:0102808	biolink:NamedThing	pelargonidin 3-O-glucoside 2''-O-glucosyltransferase activity	Catalysis of the reaction: UDP-alpha-D-glucose + pelargonidin 3-O-beta-D-glucoside <=> H+ + pelargonidin 3-O-sophoroside + UDP.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-8177									molecular_function											owl:Class	
GO:0034687	biolink:NamedThing	integrin alphaL-beta2 complex	An integrin complex that comprises one alphaL subunit and one beta2 subunit.	tmpzr1t_l9r_go_relaxed.owl	Itgal-Itgb2 complex|alphaL-beta2 integrin complex													cellular_component											owl:Class	
GO:0031986	biolink:NamedThing	proteinoplast	A leucoplast in which protein is stored.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Proteinoplast									cellular_component											owl:Class	
GO:0009516	biolink:NamedThing	leucoplast	A colorless plastid involved in the synthesis of monoterpenes.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Leucoplast									cellular_component											owl:Class	
GO:0005606	biolink:NamedThing	laminin-1 complex	A laminin complex composed of alpha1, beta1 and gamma1 polypeptide chains.	tmpzr1t_l9r_go_relaxed.owl	laminin-111 complex													cellular_component											owl:Class	
GO:0047555	biolink:NamedThing	3',5'-cyclic-GMP phosphodiesterase activity	Catalysis of the reaction: guanosine 3',5'-cyclic phosphate + H2O = guanosine 5'-phosphate.	tmpzr1t_l9r_go_relaxed.owl	cGMP-specific phosphodiesterase activity|cyclic 3',5'-GMP phosphodiesterase activity|cGMP-PDE|cGMP phosphodiesterase activity|guanosine cyclic 3',5'-phosphate phosphodiesterase activity|3',5' cyclic-GMP phosphodiesterase activity|cyclic GMP phosphodiesterase activity|cyclic guanosine 3',5'-monophosphate phosphodiesterase activity|3',5'-cyclic-GMP 5'-nucleotidohydrolase activity|cyclic guanosine 3',5'-phosphate phosphodiesterase activity				Reactome:R-HSA-418456|EC:3.1.4.35|Reactome:R-HSA-74059|RHEA:16957|MetaCyc:35-CYCLIC-GMP-PHOSPHODIESTERASE-RXN|Reactome:R-HSA-4086392							GO:0004116		molecular_function											owl:Class	
GO:0021621	biolink:NamedThing	hypoglossal nerve structural organization	The process that contributes to the act of creating the structural organization of the hypoglossal nerve. This process pertains to the physical shaping of a rudimentary structure. This motor nerve innervates all the intrinsic and all but one of the extrinsic muscles of the tongue.	tmpzr1t_l9r_go_relaxed.owl	hypoglossal nerve structural organisation|CN XII structural organization													biological_process											owl:Class	
GO:0098769	biolink:NamedThing	TIMP family protein binding	Binding to a member of the Tissue inhibitors of metalloproteinases (TIMPs) family. TIMPs are endogenous protein regulators of the matrix metalloproteinase (MMPs) family.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0001626	biolink:NamedThing	nociceptin receptor activity	Combining with the peptide nociceptin, and transmitting the signal across the membrane by activating an associated G-protein.	tmpzr1t_l9r_go_relaxed.owl	X-opioid receptor activity|OFQ receptor activity|nociceptin/orphanin-FQ receptor activity|ORPH receptor|orphanin-FQ receptor activity													molecular_function											owl:Class	
GO:0018321	biolink:NamedThing	protein glucuronylation	The modification of a protein by amino acid glucuronylation, the addition of a glucuronate group, the uronic acid derived from glucose.	tmpzr1t_l9r_go_relaxed.owl	protein amino acid glucuronylation													biological_process											owl:Class	
GO:0050626	biolink:NamedThing	trimethylamine-N-oxide reductase (cytochrome c) activity	Catalysis of the reaction: trimethylamine + 2 (ferricytochrome c)-subunit + H2O = trimethylamine-N-oxide + 2 (ferrocytochrome c)-subunit + 2 H+.	tmpzr1t_l9r_go_relaxed.owl	TOR activity|TMAO reductase activity|trimethylamine:cytochrome c oxidoreductase activity				RHEA:24236|Wikipedia:Trimethylamine_N-oxide_reductase|MetaCyc:1.7.2.3-RXN|EC:1.7.2.3									molecular_function											owl:Class	
GO:0097095	biolink:NamedThing	frontonasal suture morphogenesis	The process in which the frontonasal suture, between frontal and nasal bones, is generated and organized.	tmpzr1t_l9r_go_relaxed.owl	nasofrontal suture morphogenesis							pr	2011-07-05T02:57:46Z					biological_process											owl:Class	
GO:0050065	biolink:NamedThing	lysine-pyruvate 6-transaminase activity	Catalysis of the reaction: L-lysine + pyruvate = L-alanine + L-allysine.	tmpzr1t_l9r_go_relaxed.owl	lysine--pyruvate 6-aminotransferase activity|Lys-AT|lysine-pyruvate aminotransferase activity|L-lysine:pyruvate aminotransferase activity				MetaCyc:LYSINE--PYRUVATE-6-AMINOTRANSFERASE-RXN|MetaCyc:PWY-5324|RHEA:19393|EC:2.6.1.71|KEGG_REACTION:R00453									molecular_function											owl:Class	
GO:0002436	biolink:NamedThing	immune complex clearance by monocytes and macrophages	The process of immune complex clearance by monocytes or macrophages.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0002815	biolink:NamedThing	biosynthetic process of antibacterial peptides active against Gram-positive bacteria	The chemical reactions and pathways resulting in the formation of an antibacterial peptide with activity against Gram-positive bacteria.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0050333	biolink:NamedThing	thiamin-triphosphatase activity	Catalysis of the reaction: H(2)O + thiamine triphosphate = H(+) + phosphate + thiamine diphosphate.	tmpzr1t_l9r_go_relaxed.owl	thiamine-triphosphatase activity|ThTPase activity|thiamine-triphosphate phosphohydrolase activity				EC:3.6.1.28|Reactome:R-HSA-965067|KEGG_REACTION:R00618|MetaCyc:THIAMIN-TRIPHOSPHATASE-RXN|RHEA:11744							GO:0048253		molecular_function											owl:Class	
GO:0050414	biolink:NamedThing	formimidoylaspartate deiminase activity	Catalysis of the reaction: N-formimidoyl-L-aspartate + H2O = N-formyl-L-aspartate + NH3.	tmpzr1t_l9r_go_relaxed.owl	N-formimidoyl-L-aspartate iminohydrolase activity|formiminoaspartate deiminase activity				MetaCyc:FORMIMINOASPARTATE-DEIMINASE-RXN|RHEA:13661|EC:3.5.3.5									molecular_function											owl:Class	
GO:0062147	biolink:NamedThing	L-lysine 4-chlorinase activity	Catalysis of the reaction: 2-oxoglutarate + chloride + H(+) + L-lysine + O2 = 4-chloro-L-lysine + CO2 + H2O + succinate.	tmpzr1t_l9r_go_relaxed.owl					RHEA:59884			dph	2019-09-02T17:01:46Z					molecular_function											owl:Class	
GO:0031313	biolink:NamedThing	extrinsic component of endosome membrane	The component of an endosome membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.	tmpzr1t_l9r_go_relaxed.owl	extrinsic to endosome membrane													cellular_component											owl:Class	
GO:0008314	biolink:NamedThing	gurken signaling pathway	The series of molecular signals generated as a consequence of an epidermal growth factor receptor binding to a ligand Gurken.	tmpzr1t_l9r_go_relaxed.owl	signaling by Gurken|gurken receptor signalling pathway|gurken receptor signaling pathway|gurken-activated signaling pathway													biological_process											owl:Class	
GO:0071125	biolink:NamedThing	alphaV-beta3 integrin-EGFR complex	A protein complex that consists of an alphaV-beta3 integrin complex bound to epidermal growth factor receptor.	tmpzr1t_l9r_go_relaxed.owl	ITGAV-ITGB3-EGFR complex							mah	2009-11-13T02:23:18Z					cellular_component											owl:Class	
GO:0009884	biolink:NamedThing	cytokinin receptor activity	Combining with a cytokinin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0006408	biolink:NamedThing	snRNA export from nucleus	The directed movement of snRNA from the nucleus to the cytoplasm.	tmpzr1t_l9r_go_relaxed.owl	snRNA transport from nucleus to cytoplasm|snRNA export out of nucleus|snRNA export from cell nucleus|snRNA-nucleus export													biological_process											owl:Class	
GO:0008542	biolink:NamedThing	visual learning	Any process in an organism in which a change in behavior of an individual occurs in response to repeated exposure to a visual cue.	tmpzr1t_l9r_go_relaxed.owl	spatial learning													biological_process											owl:Class	
GO:0045146	biolink:NamedThing	initiation of acetate catabolic process by acetate	The activation, by acetate, of the chemical reactions and pathways resulting in the breakdown of acetate.	tmpzr1t_l9r_go_relaxed.owl	initiation of acetate breakdown by acetate|initiation of acetate degradation by acetate													biological_process											owl:Class	
GO:0043077	biolink:NamedThing	initiation of acetate catabolic process	The activation of the chemical reactions and pathways resulting in the breakdown of acetate.	tmpzr1t_l9r_go_relaxed.owl	initiation of acetate degradation|initiation of acetate breakdown|initiation of acetate catabolism													biological_process											owl:Class	
GO:0045025	biolink:NamedThing	mitochondrial degradosome	A mitochondrial protein complex with 3' to 5' exoribonuclease activity that participates in intron-independent turnover and processing of mitochondrial transcripts. In humans, the mitochondrial degradosome is a pentameric complex, and in yeast it exists as a heterodimer.	tmpzr1t_l9r_go_relaxed.owl	mtEXO													cellular_component											owl:Class	
GO:0018926	biolink:NamedThing	methanesulfonic acid metabolic process	The chemical reactions and pathways involving methanesulfonic acid, a strong acid produced by the oxidation of dimethyl sulfide.	tmpzr1t_l9r_go_relaxed.owl	methanesulphonic acid metabolism|methanesulfonic acid metabolism|methanesulphonic acid metabolic process				UM-BBD_pathwayID:msa									biological_process											owl:Class	
GO:0047826	biolink:NamedThing	D-lysine 5,6-aminomutase activity	Catalysis of the reaction: D-lysine = 2,5-diaminohexanoate.	tmpzr1t_l9r_go_relaxed.owl	D-alpha-lysine mutase activity|adenosylcobalamin-dependent D-lysine 5,6-aminomutase activity|D-2,6-diaminohexanoate 5,6-aminomutase activity				EC:5.4.3.4|RHEA:18241|KEGG_REACTION:R02852|MetaCyc:D-LYSINE-56-AMINOMUTASE-RXN									molecular_function											owl:Class	
GO:0033300	biolink:NamedThing	dehydroascorbic acid transmembrane transporter activity	Enables the transfer of dehydroascorbate, 5-(1,2-dihydroxyethyl)furan-2,3,4(5H)-trione, from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	dehydroascorbate transporter activity|dehydroascorbic acid transporter activity				RHEA:60380|Reactome:R-HSA-198818									molecular_function											owl:Class	
GO:0071441	biolink:NamedThing	negative regulation of histone H3-K14 acetylation	Any process that stops, prevents, or reduces the frequency, rate or extent of the addition of an acetyl group to histone H3 at position 14 of the histone.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of histone H3-K14 acetylation|negative regulation of histone H3K14 acetylation|negative regulation of histone H3 acetylation at K14|down regulation of histone H3-K14 acetylation|inhibition of histone H3-K14 acetylation|downregulation of histone H3-K14 acetylation							mah	2009-12-16T03:28:23Z					biological_process											owl:Class	
GO:1903264	biolink:NamedThing	nitrate reductase activity involved in anaerobic electron transport chain	Any nitrate reductase activity that is involved in anaerobic electron transport chain.	tmpzr1t_l9r_go_relaxed.owl	respiratory nitrate reductase activity involved in anaerobic electron transport chain|nitrite:acceptor oxidoreductase involved in anaerobic electron transport chain|nitrite:(acceptor) oxidoreductase involved in anaerobic electron transport chain|nitrate reductase (acceptor) involved in anaerobic electron transport chain							dos	2014-08-07T10:07:07Z					molecular_function											owl:Class	
GO:0002603	biolink:NamedThing	positive regulation of antigen processing and presentation of polysaccharide antigen via MHC class II	Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of polysaccharide antigen via MHC class II.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of antigen processing and presentation of polysaccharide antigen via MHC class II|activation of antigen processing and presentation of polysaccharide antigen via MHC class II|stimulation of antigen processing and presentation of polysaccharide antigen via MHC class II|up regulation of antigen processing and presentation of polysaccharide antigen via MHC class II|upregulation of antigen processing and presentation of polysaccharide antigen via MHC class II|positive regulation of polysaccharide antigen processing and presentation via MHC class II													biological_process											owl:Class	
GO:0002601	biolink:NamedThing	regulation of antigen processing and presentation of polysaccharide antigen via MHC class II	Any process that modulates the frequency, rate, or extent of antigen processing and presentation of polysaccharide antigen via MHC class II.	tmpzr1t_l9r_go_relaxed.owl	regulation of polysaccharide antigen processing and presentation via MHC class II													biological_process											owl:Class	
GO:0120173	biolink:NamedThing	regulation of actin filament bundle convergence involved in mitotic contractile ring assembly	Any process that modulates the frequency, rate or extent of actin filament bundle convergence involved in mitotic contractile ring assembly.	tmpzr1t_l9r_go_relaxed.owl								krc	2018-05-31T18:08:01Z					biological_process											owl:Class	
GO:0034885	biolink:NamedThing	gamma-N-formylaminovinylacetate hydrolase activity	Catalysis of the reaction: gamma-N-formylaminovinylacetate + H2O = gamma-aminovinylacetate + HCOOH.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r1350									molecular_function											owl:Class	
GO:0150020	biolink:NamedThing	basal dendrite arborization	The process in which the anatomical structures of a dendritic tree are generated on the basal neuron side and organized into dendritic branches.	tmpzr1t_l9r_go_relaxed.owl								bc	2017-12-22T11:32:31Z					biological_process											owl:Class	
GO:0045429	biolink:NamedThing	positive regulation of nitric oxide biosynthetic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nitric oxide.	tmpzr1t_l9r_go_relaxed.owl	up regulation of nitric oxide biosynthetic process|up-regulation of nitric oxide biosynthetic process|activation of nitric oxide biosynthetic process|stimulation of nitric oxide biosynthetic process|upregulation of nitric oxide biosynthetic process|positive regulation of nitric oxide biosynthesis|positive regulation of nitric oxide synthesis|positive regulation of nitric oxide formation|positive regulation of nitric oxide anabolism													biological_process											owl:Class	
GO:1990322	biolink:NamedThing	collagen type XXIII trimer	A collagen homotrimer of alpha1(XXIII) chains; type XXIII collagen triple helices span the plasma membrane.	tmpzr1t_l9r_go_relaxed.owl								bhm	2014-03-14T22:01:00Z					cellular_component											owl:Class	
GO:0033999	biolink:NamedThing	chondroitin B lyase activity	Catalysis of the reaction: dermatan sulfate = n 4-deoxy-beta-D-gluc-4-enuronosyl-(1,3)-N-acetyl-D-galactosamine 4-sulfate. This reaction is the eliminative cleavage of dermatan sulfate containing 1,4-beta-D-hexosaminyl and 1,3-beta-D-glucurosonyl or 1,3-alpha-L-iduronosyl linkages to disaccharides containing 4-deoxy-beta-D-gluc-4-enuronosyl groups to yield a 4,5-unsaturated dermatan-sulfate disaccharide (DeltaUA-GalNAC-4S). Chondroitin sulfate B is also known as dermatan sulfate.	tmpzr1t_l9r_go_relaxed.owl	ChnB|chonB|dermatan sulfate lyase activity|chondroitinase B activity				MetaCyc:4.2.2.19-RXN|EC:4.2.2.19									molecular_function											owl:Class	
GO:0102415	biolink:NamedThing	quercetin gentiobioside 1,6-glucosyltransferase activity	Catalysis of the reaction: quercetin-3-gentiobioside + UDP-alpha-D-glucose <=> quercetin-3-gentiotrioside + UDP + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-13798									molecular_function											owl:Class	
GO:0021563	biolink:NamedThing	glossopharyngeal nerve development	Various sensory and motor branches of the glossopharyngeal nerve supply nerve connections to the pharynx and back of the tongue. The branchial motor component contains motor fibers that innervate muscles that elevate the pharynx and larynx, and the tympanic branch supplies parasympathetic fibers to the otic ganglion.	tmpzr1t_l9r_go_relaxed.owl	CN IX development|cranial nerve IX development|cranial nerve 9 development													biological_process											owl:Class	
GO:0102795	biolink:NamedThing	1-naphthaldehyde:oxygen oxidoreductase activity	Catalysis of the reaction: 1-naphthaldehyde + O2 + H2O = H+ + 1-naphthoate + hydrogen peroxide.	tmpzr1t_l9r_go_relaxed.owl					EC:1.2.3.9|MetaCyc:RXN-8090									molecular_function											owl:Class	
GO:0051968	biolink:NamedThing	positive regulation of synaptic transmission, glutamatergic	Any process that activates, maintains or increases the frequency, rate or extent of glutamatergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glutamate.	tmpzr1t_l9r_go_relaxed.owl	stimulation of synaptic transmission, glutamatergic|upregulation of synaptic transmission, glutamatergic|up regulation of synaptic transmission, glutamatergic|activation of synaptic transmission, glutamatergic|up-regulation of synaptic transmission, glutamatergic													biological_process											owl:Class	
GO:0010352	biolink:NamedThing	lithium ion export across the plasma membrane	The directed movement of lithium ion out of a cell or organelle.	tmpzr1t_l9r_go_relaxed.owl	lithium ion efflux|lithium export|lithium ion export													biological_process											owl:Class	
GO:0019463	biolink:NamedThing	glycine catabolic process to creatine	The chemical reactions and pathways resulting in the breakdown of glycine into other compounds, including creatine.	tmpzr1t_l9r_go_relaxed.owl	glycine breakdown to creatine|glycine degradation to creatine				MetaCyc:GLYCGREAT-PWY									biological_process											owl:Class	
GO:0006600	biolink:NamedThing	creatine metabolic process	The chemical reactions and pathways involving creatine (N-(aminoiminomethyl)-N-methylglycine), a compound synthesized from the amino acids arginine, glycine, and methionine that occurs in muscle.	tmpzr1t_l9r_go_relaxed.owl	creatine metabolism													biological_process											owl:Class	
GO:0070415	biolink:NamedThing	trehalose metabolism in response to cold stress	The chemical reactions and pathways involving trehalose that occur as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that organism.	tmpzr1t_l9r_go_relaxed.owl	trehalose metabolic process involved in response to cold stress													biological_process											owl:Class	
GO:0102633	biolink:NamedThing	flaviolin monooxygenase activity	Catalysis of the reaction: flaviolin-2-olate + NADH + H+ + O2 <=> mompain + NAD + H2O.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-15585									molecular_function											owl:Class	
GO:1905189	biolink:NamedThing	regulation of metaphase/anaphase transition of meiosis II	Any process that modulates the frequency, rate or extent of metaphase/anaphase transition of meiosis II.	tmpzr1t_l9r_go_relaxed.owl	regulation of meiosis II metaphase/anaphase transition							vw	2016-05-10T16:46:49Z					biological_process											owl:Class	
GO:0007608	biolink:NamedThing	sensory perception of smell	The series of events required for an organism to receive an olfactory stimulus, convert it to a molecular signal, and recognize and characterize the signal. Olfaction involves the detection of chemical composition of an organism's ambient medium by chemoreceptors. This is a neurological process.	tmpzr1t_l9r_go_relaxed.owl	sense of smell|scent perception|olfaction|smell perception				Wikipedia:Olfaction									biological_process											owl:Class	
GO:0070877	biolink:NamedThing	microprocessor complex	A protein complex that binds to heme and to pri-miRNAs, and is required for the formation of a pre-microRNA (pre-miRNA), the initial step of microRNA (miRNA) biogenesis. The complex is composed of the double-stranded-RNA-specific RNase Drosha (also called RNASEN) and the RNA-binding protein DGCR8 (heme-free or heme-bound forms). Within the complex, DGCR8 function as a molecular anchor necessary for the recognition of pri-miRNA at dsRNA-ssRNA junction and directs RNASEN/Drosha to cleave the 3' and 5' strands of a stem-loop to release hairpin-shaped pre-miRNAs.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-08-20T03:56:26Z					cellular_component											owl:Class	
GO:1905741	biolink:NamedThing	calcium export from the mitochondrion involved in positive regulation of presynaptic cytosolic calcium concentration	Any mitochondrial calcium release that is involved in positive regulation of presynaptic cytosolic calcium concentration.	tmpzr1t_l9r_go_relaxed.owl	calcium ion transmembrane export from mitochondrion involved in positive regulation of presynaptic cytosolic calcium concentration|mitochondrial calcium release involved in positive regulation of presynaptic cytosolic calcium concentration							dos	2016-12-06T10:05:01Z					biological_process											owl:Class	
GO:0030527	biolink:NamedThing	structural constituent of chromatin	The action of a molecule that contributes to the structural integrity of chromatin.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0090357	biolink:NamedThing	regulation of tryptophan metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving tryptophan, the chiral amino acid 2-amino-3-(1H-indol-3-yl)propanoic acid.	tmpzr1t_l9r_go_relaxed.owl	regulation of tryptophan metabolism							tb	2010-06-29T02:38:48Z					biological_process											owl:Class	
GO:0098975	biolink:NamedThing	postsynapse of neuromuscular junction	The postsynapse of a neuromuscular junction. In vertebrate muscles this includes the motor end-plate, consisting of postjunctional folds of the sarcolemma.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0006070	biolink:NamedThing	octanol metabolic process	The chemical reactions and pathways involving octanol, the 8-carbon alcohol with the formula C8H17OH.	tmpzr1t_l9r_go_relaxed.owl	octanol metabolism													biological_process											owl:Class	
GO:0007121	biolink:NamedThing	bipolar cellular bud site selection	The process of defining subsequent sites of bud emergence such that budding takes place at alternating poles of a budding cell.	tmpzr1t_l9r_go_relaxed.owl	bipolar bud site selection|bipolar budding|polar budding													biological_process											owl:Class	
GO:1905578	biolink:NamedThing	regulation of ERBB3 signaling pathway	Any process that modulates the frequency, rate or extent of ERBB3 signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	regulation of ERBB3 signalling pathway|regulation of HER3 signaling pathway|regulation of receptor tyrosine-protein kinase erbB-3 signaling pathway							als	2016-10-19T11:46:55Z					biological_process											owl:Class	
GO:0061332	biolink:NamedThing	Malpighian tubule bud morphogenesis	The morphogenetic process in which a bud forms from the embryonic hindgut tube to form the Malpighian tubule. A bud is a protrusion that forms from the tube by localized changes in cell shape and position.	tmpzr1t_l9r_go_relaxed.owl	Malpighian tubule formation							dph	2010-09-28T01:39:32Z					biological_process											owl:Class	
GO:0060572	biolink:NamedThing	morphogenesis of an epithelial bud	The morphogenetic process in which a bud forms from an epithelial sheet. A bud is a protrusion that forms form the sheet by localized folding.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-04-30T09:38:35Z					biological_process											owl:Class	
GO:2001176	biolink:NamedThing	regulation of mediator complex assembly	Any process that modulates the frequency, rate or extent of mediator complex assembly.	tmpzr1t_l9r_go_relaxed.owl								yaf	2011-11-02T11:22:18Z					biological_process											owl:Class	
GO:1904053	biolink:NamedThing	positive regulation of protein targeting to vacuole involved in autophagy	Any process that activates or increases the frequency, rate or extent of protein targeting to vacuole involved in autophagy.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of protein targeting to vacuole involved in autophagy|activation of protein targeting to vacuole involved in autophagy|upregulation of protein targeting to vacuole involved in autophagy|up regulation of protein targeting to vacuole involved in autophagy					An example of this is SMURF1 in human (UniProt symbol Q9HCE7) in PMID:22020285 (inferred from mutant phenotype).		pad	2015-03-17T13:54:27Z					biological_process											owl:Class	
GO:0102986	biolink:NamedThing	trehalose synthase activity	Catalysis of the reaction: an NDP-alpha-D-glucose + D-glucopyranose <=> alpha,alpha-trehalose + H+ + a nucleoside diphosphate.	tmpzr1t_l9r_go_relaxed.owl					RHEA:47416|MetaCyc:RXN-9603|EC:2.4.1.245									molecular_function											owl:Class	
GO:0008087	biolink:NamedThing	light-activated voltage-gated calcium channel complex	A protein complex that forms a transmembrane channel through which calcium ions may cross a cell membrane in response to changes in membrane potential generated in response to a light stimulus.	tmpzr1t_l9r_go_relaxed.owl	light-activated voltage gated calcium channel complex|light-activated voltage-dependent calcium channel complex|light-activated voltage-sensitive calcium channel complex													cellular_component											owl:Class	
GO:1900445	biolink:NamedThing	positive regulation of filamentous growth of a population of unicellular organisms in response to biotic stimulus	Any process that activates or increases the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to biotic stimulus.	tmpzr1t_l9r_go_relaxed.owl	up regulation of filamentous growth of a population of unicellular organisms in response to biotic stimulus|activation of filamentous growth of a population of unicellular organisms in response to biotic stimulus|upregulation of filamentous growth of a population of unicellular organisms in response to biotic stimulus|up-regulation of filamentous growth of a population of unicellular organisms in response to biotic stimulus							di	2012-04-25T05:56:35Z					biological_process											owl:Class	
GO:0046322	biolink:NamedThing	negative regulation of fatty acid oxidation	Any process that stops, prevents, or reduces the frequency, rate or extent of fatty acid oxidation.	tmpzr1t_l9r_go_relaxed.owl	inhibition of fatty acid oxidation|down-regulation of fatty acid oxidation|down regulation of fatty acid oxidation|downregulation of fatty acid oxidation													biological_process											owl:Class	
GO:0072759	biolink:NamedThing	cellular response to topoisomerase inhibitor	Any process that results in a change in state or activity of a (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a topoisomerase inhibitor stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2012-11-09T11:38:08Z					biological_process											owl:Class	
GO:0072758	biolink:NamedThing	response to topoisomerase inhibitor	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a topoisomerase inhibitor stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2012-11-09T11:34:51Z					biological_process											owl:Class	
GO:1904282	biolink:NamedThing	regulation of antigen processing and presentation of endogenous peptide antigen via MHC class I	Any process that modulates the frequency, rate or extent of antigen processing and presentation of endogenous peptide antigen via MHC class I.	tmpzr1t_l9r_go_relaxed.owl	regulation of antigen processing, endogenous antigen via major histocompatibility complex class I|regulation of antigen presentation, endogenous peptide antigen|regulation of antigen processing, endogenous antigen via MHC class I|regulation of endogenous peptide antigen processing and presentation via MHC class I							rl	2015-06-04T12:05:28Z					biological_process											owl:Class	
GO:0021505	biolink:NamedThing	neural fold folding	The process of folding the neuroepithelium around the medial hinge point to create the neural elevations, and around the lateral hinge points to produce convergence of the folds.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0003185	biolink:NamedThing	sinoatrial valve morphogenesis	The process in which the structure of the sinoatrial valve is generated and organized.	tmpzr1t_l9r_go_relaxed.owl	SA valve morphogenesis							dph	2009-10-08T12:04:52Z					biological_process											owl:Class	
GO:0004845	biolink:NamedThing	uracil phosphoribosyltransferase activity	Catalysis of the reaction: diphosphate + UMP = 5-phospho-alpha-D-ribose 1-diphosphate + uracil.	tmpzr1t_l9r_go_relaxed.owl	UMP:diphosphate phospho-alpha-D-ribosyltransferase activity|UMP pyrophosphorylase activity|UMP diphosphorylase activity|UPRTase activity|uridylic pyrophosphorylase activity|uridine 5'-phosphate pyrophosphorylase activity|uridylate pyrophosphorylase activity|UMP:pyrophosphate phosphoribosyltransferase activity|uridine monophosphate pyrophosphorylase activity				MetaCyc:URACIL-PRIBOSYLTRANS-RXN|RHEA:13017|KEGG_REACTION:R00966|EC:2.4.2.9									molecular_function											owl:Class	
GO:1904630	biolink:NamedThing	cellular response to diterpene	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diterpene stimulus.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-08-28T13:52:43Z					biological_process											owl:Class	
GO:1904629	biolink:NamedThing	response to diterpene	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diterpene stimulus.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-08-28T13:52:37Z					biological_process											owl:Class	
GO:0033650	biolink:NamedThing	host cell mitochondrion	A semiautonomous, self replicating organelle as found in host cells that occurs in varying numbers, shapes, and sizes in the cell cytoplasm. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	host mitochondria													cellular_component											owl:Class	
GO:0070939	biolink:NamedThing	Dsl1/NZR complex	A multisubunit tethering complex, i.e. a protein complex involved in mediating the initial interaction between vesicles and the membranes with which they fuse, that is involved in trafficking from the Golgi apparatus to the ER. In Saccharomyces cerevisiae the Dsl1p complex contains Dsl1p, Tip20p, and Sec39p.	tmpzr1t_l9r_go_relaxed.owl	NZR complex|Dsl1p complex|CATCHR family complex					See also the molecular function term 'acetolactate synthase activity ; GO:0003984'.		mah	2009-09-22T03:41:38Z					cellular_component											owl:Class	
GO:0005785	biolink:NamedThing	signal recognition particle receptor complex	A transmembrane heterodimeric protein located in the membrane of the rough endoplasmic reticulum. Both subunits contain GTPase domains with which signal recognition particle interacts. In the presence of GTP and SRP receptor, SRP is released from the ribosome-nascent chain complex.	tmpzr1t_l9r_go_relaxed.owl	SR complex|docking protein complex													cellular_component											owl:Class	
GO:0061795	biolink:NamedThing	Golgi lumen acidification	Any process that reduces the pH of the Golgi lumen, measured by the concentration of the hydrogen ion.	tmpzr1t_l9r_go_relaxed.owl								dph	2016-10-05T08:42:40Z					biological_process											owl:Class	
GO:0034967	biolink:NamedThing	Set3 complex	A histone deacetylase complex that is involved in transcriptional regulation. In S. cerevisiae, this complex consists of Set3p, Snt1p, Hos4p, Sif2p, Cpr1p, Hos2p, and Hst1p.	tmpzr1t_l9r_go_relaxed.owl	SET3C|HDAC3 complex													cellular_component											owl:Class	
GO:0120245	biolink:NamedThing	terminal acetylenic compound catabolic process	The chemical reactions and pathways resulting in the breakdown of a terminal acetylenic compound, a compound which contains a terminal alkyne moiety in which a carbon of the carbon-carbon triple bond (aka C#C) moiety is attached to a hydrogen atom.	tmpzr1t_l9r_go_relaxed.owl	terminal alkyne substituted compound degradation|terminal alkyne substituted compound catabolism|terminal alkyne substituted compound catabolic process|terminal alkyne substituted compound breakdown	https://github.com/geneontology/go-ontology/issues/19842						krc	2020-08-17T22:48:58Z					biological_process											owl:Class	
GO:0120244	biolink:NamedThing	terminal acetylenic compound metabolic process	The chemical reactions and pathways involving a terminal acetylenic compound, involving a terminal acetylenic compound, a compound which contains a terminal alkyne moiety in which which a carbon of the carbon-carbon triple bond (aka C#C) moiety is attached to a hydrogen atom.	tmpzr1t_l9r_go_relaxed.owl	terminal alkyne substituted compound metabolic process|terminal alkyne substituted compound metabolism	https://github.com/geneontology/go-ontology/issues/19842						krc	2020-08-17T22:41:12Z					biological_process											owl:Class	
GO:0018617	biolink:NamedThing	4-aminobenzenesulfonate 3,4-dioxygenase (deaminating) activity	Catalysis of the reaction: 4-aminobenzenesulfonate + 2 H+ + O2 + 2 e- = NH3 + 4-sulfocatechol.	tmpzr1t_l9r_go_relaxed.owl	4-aminobenzenesulphonate 3,4-dioxygenase (deaminating) activity				UM-BBD_reactionID:r0580|EC:1.14.12.-									molecular_function											owl:Class	
GO:0006003	biolink:NamedThing	fructose 2,6-bisphosphate metabolic process	The chemical reactions and pathways involving fructose 2,6-bisphosphate. The D enantiomer is an important regulator of the glycolytic and gluconeogenic pathways. It inhibits fructose 1,6-bisphosphatase and activates phosphofructokinase.	tmpzr1t_l9r_go_relaxed.owl	fructose 2,6-bisphosphate metabolism													biological_process											owl:Class	
GO:0043561	biolink:NamedThing	regulation of translational initiation in response to osmotic stress	Any process that modulates the frequency, rate or extent of translation initiation, as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0051683	biolink:NamedThing	establishment of Golgi localization	The directed movement of the Golgi to a specific location.	tmpzr1t_l9r_go_relaxed.owl	establishment of Golgi localisation|establishment of Golgi apparatus localization|establishment of Golgi body localization													biological_process											owl:Class	
GO:0006789	biolink:NamedThing	bilirubin conjugation	The chemical reactions and pathways resulting in the formation of bilirubin monoglucuronide or bilirubin diglucuronide, water-soluble derivatives of bilirubin.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0102048	biolink:NamedThing	indole-3-acetyl-isoleucine synthetase activity	Catalysis of the reaction: indole-3-acetate + L-isoleucine + ATP(4-) <=> H+ + indole-3-acetyl-isoleucine + AMP(2-) + diphosphoric acid.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-10430									molecular_function											owl:Class	
GO:0070076	biolink:NamedThing	histone lysine demethylation	The modification of a histone by the removal of a methyl group from a lysine residue.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1903938	biolink:NamedThing	cellular response to acrylamide	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acrylamide stimulus.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-02-12T22:00:34Z					biological_process											owl:Class	
GO:1901869	biolink:NamedThing	ecgonine methyl ester biosynthetic process	The chemical reactions and pathways resulting in the formation of ecgonine methyl ester.	tmpzr1t_l9r_go_relaxed.owl	ecgonine methyl ester anabolism|ecgonine methyl ester biosynthesis|ecgonine methyl ester synthesis|ecgonine methyl ester formation							ms	2013-02-04T11:58:25Z					biological_process											owl:Class	
GO:1901867	biolink:NamedThing	ecgonine methyl ester metabolic process	The chemical reactions and pathways involving ecgonine methyl ester.	tmpzr1t_l9r_go_relaxed.owl	ecgonine methyl ester metabolism							ms	2013-02-04T11:58:14Z					biological_process											owl:Class	
GO:2000587	biolink:NamedThing	negative regulation of platelet-derived growth factor receptor-beta signaling pathway	Any process that stops, prevents or reduces the frequency, rate or extent of platelet-derived growth factor receptor-beta signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of PDGF receptor-beta signaling pathway|negative regulation of PDGFR-beta signaling pathway|negative regulation of betaPDGF receptor signaling pathway|negative regulation of platelet-derived growth factor receptor-beta signalling pathway							bf	2011-04-07T03:27:54Z					biological_process											owl:Class	
GO:0010290	biolink:NamedThing	chlorophyll catabolite transmembrane transporter activity	Enables the directed movement of chlorophyll catabolites such as non-fluorescent chlorophyll catabolites (NCCs), from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0033128	biolink:NamedThing	negative regulation of histone phosphorylation	Any process that stops, prevents, or reduces the frequency, rate or extent of the addition of one or more phosphate groups to a histone protein.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:2001110	biolink:NamedThing	negative regulation of lens epithelial cell proliferation	Any process that stops, prevents or reduces the frequency, rate or extent of lens epithelial cell proliferation.	tmpzr1t_l9r_go_relaxed.owl								yaf	2011-09-30T02:04:57Z					biological_process											owl:Class	
GO:0006251	biolink:NamedThing	dCDP catabolic process	The chemical reactions and pathways resulting in the breakdown of dCDP, deoxycytidine 5'-diphosphate.	tmpzr1t_l9r_go_relaxed.owl	dCDP degradation|dCDP breakdown|dCDP catabolism													biological_process											owl:Class	
GO:0036412	biolink:NamedThing	acetyl-CoA:oxalate CoA-transferase	Catalysis of the reaction: acetyl-CoA + oxalate = acetate + oxalyl-CoA.	tmpzr1t_l9r_go_relaxed.owl					RHEA:37883			bf	2013-08-22T13:43:25Z					molecular_function											owl:Class	
GO:1990692	biolink:NamedThing	trans-Golgi-derived vesicle fusion with Golgi medial cisterna membrane	The joining of the lipid bilayer membrane around a trans-Golgi-derived vesicle to the lipid bilayer membrane around the medial-Golgi cisterna. Such vesicles include COPI-coated transport vesicles involved in retrograde transport.	tmpzr1t_l9r_go_relaxed.owl	trans-Golgi-derived vesicle fusion with medial-Golgi cisterna membrane							bhm	2015-03-12T09:54:02Z					biological_process											owl:Class	
GO:0051890	biolink:NamedThing	regulation of cardioblast differentiation	Any process that modulates the frequency, rate or extent of cardioblast differentiation, the process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0003876	biolink:NamedThing	AMP deaminase activity	Catalysis of the reaction: AMP + H2O = IMP + NH3.	tmpzr1t_l9r_go_relaxed.owl	AMP aminase activity|5-AMP deaminase activity|adenyl deaminase activity|5-adenylic acid deaminase activity|5-adenylate deaminase activity|adenosine 5-monophosphate deaminase activity|AMP aminohydrolase activity|adenylic deaminase activity|adenylate deaminase reaction|adenylate aminohydrolase activity|adenylate desaminase activity|adenosine 5-phosphate aminohydrolase activity|myoadenylate deaminase activity|adenylic acid deaminase activity|adenylate deaminase activity|adenosine monophosphate deaminase activity				RHEA:14777|MetaCyc:AMP-DEAMINASE-RXN|Reactome:R-HSA-76590|EC:3.5.4.6									molecular_function											owl:Class	
GO:0047623	biolink:NamedThing	adenosine-phosphate deaminase activity	Catalysis of the reaction: an adenosine-phosphate + H20 = an inosine phosphate + NH3. Catalyzes the deamination of AMP, ADP or ATP.	tmpzr1t_l9r_go_relaxed.owl	adenosine (phosphate) deaminase activity|adenine nucleotide deaminase activity|adenosine-phosphate aminohydrolase activity				MetaCyc:ADENOSINE-PHOSPHATE-DEAMINASE-RXN|EC:3.5.4.17	Consider instead annotating to one of the more specific terms: AMP deaminase activity ; GO:0003876, ADP deaminase activity ; GO:0047629, or ATP deaminase activity ; GO:0047692.								molecular_function											owl:Class	
GO:0009257	biolink:NamedThing	10-formyltetrahydrofolate biosynthetic process	The chemical reactions and pathways resulting in the formation of 10-formyltetrahydrofolate, the formylated derivative of tetrahydrofolate.	tmpzr1t_l9r_go_relaxed.owl	10-formyltetrahydrofolate anabolism|10-formyltetrahydrofolate synthesis|10-formyl-THF biosynthesis|10-formyltetrahydrofolate biosynthesis|10-formyltetrahydrofolate formation|10-formyl-THF biosynthetic process				MetaCyc:1CMET2-PWY|MetaCyc:PWY-3841									biological_process											owl:Class	
GO:0009256	biolink:NamedThing	10-formyltetrahydrofolate metabolic process	The chemical reactions and pathways involving 10-formyltetrahydrofolate, the formylated derivative of tetrahydrofolate.	tmpzr1t_l9r_go_relaxed.owl	10-formyltetrahydrofolate metabolism|10-formyl-THF metabolic process|10-formyl-THF metabolism													biological_process											owl:Class	
GO:0036163	biolink:NamedThing	3-hexaprenyl-4-hydroxy-5-methoxybenzoic acid decarboxylase activity	Catalysis of the reaction: 3-hexaprenyl-4-hydroxy-5-methoxybenzoic acid -> 2-hexaprenyl-6-methoxyphenol + CO2.	tmpzr1t_l9r_go_relaxed.owl					KEGG_REACTION:R06866|RHEA:44768			bf	2012-03-26T01:49:54Z					molecular_function											owl:Class	
GO:0018510	biolink:NamedThing	phloroglucinol reductase activity	Catalysis of the reaction: dihydrophloroglucinol + NADP(+) = H(+) + NADPH + phloroglucinol.	tmpzr1t_l9r_go_relaxed.owl	dihydrophloroglucinol:NADP+ oxidoreductase activity				UM-BBD_reactionID:r0007|EC:1.3.1.57|RHEA:10080|MetaCyc:R5-RXN|KEGG_REACTION:R05308									molecular_function											owl:Class	
GO:0051332	biolink:NamedThing	meiotic S phase	The cell cycle phase, following G1, during which DNA synthesis takes place as part of a meiotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl	S phase of meiotic cell cycle|S-phase of meiotic cell cycle					Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).								biological_process											owl:Class	
GO:1903810	biolink:NamedThing	L-histidine import across plasma membrane	The directed movement of L-histidine from outside of a cell, across the plasma membrane and into the cytosol.	tmpzr1t_l9r_go_relaxed.owl	histidine import|L-histidine import into cell|L-histidine import							dph	2012-10-05T10:20:50Z			GO:0090466|GO:0061460		biological_process											owl:Class	
GO:0070983	biolink:NamedThing	dendrite guidance	The process in which the migration of a dendrite is directed to a specific target site in response to a combination of attractive and repulsive cues.	tmpzr1t_l9r_go_relaxed.owl	dendritic guidance							mah	2009-10-27T03:53:23Z					biological_process											owl:Class	
GO:0018578	biolink:NamedThing	protocatechuate 3,4-dioxygenase activity	Catalysis of the reaction: 3,4-dihydroxybenzoate + O2 = 3-carboxy-cis,cis-muconate.	tmpzr1t_l9r_go_relaxed.owl	protocatechuic 3,4-oxygenase activity|protocatechuate:oxygen 3,4-oxidoreductase (decyclizing)|protocatechuic acid oxidase activity|protocatechuate oxygenase activity|protocatechuic 3,4-dioxygenase activity				EC:1.13.11.3|MetaCyc:PROTOCATECHUATE-34-DIOXYGENASE-RXN|UM-BBD_reactionID:r0143|RHEA:10084									molecular_function											owl:Class	
GO:1990248	biolink:NamedThing	regulation of transcription from RNA polymerase II promoter in response to DNA damage	Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of DNA damage.	tmpzr1t_l9r_go_relaxed.owl								pg	2013-12-04T13:28:04Z					biological_process											owl:Class	
GO:0099047	biolink:NamedThing	clearance of foreign intracellular RNA	A defense process that protects an organism from invading foreign RNA.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0042613	biolink:NamedThing	MHC class II protein complex	A transmembrane protein complex composed of an MHC class II alpha and MHC class II beta chain, and with or without a bound peptide or polysaccharide antigen.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:1902662	biolink:NamedThing	regulation of peptidyl-L-cysteine S-palmitoylation	Any process that modulates the frequency, rate or extent of peptidyl-L-cysteine S-palmitoylation.	tmpzr1t_l9r_go_relaxed.owl	regulation of peptidyl-S-palmitoyl-L-cysteine anabolism from peptidyl-cysteine|regulation of peptidyl-S-palmitoyl-L-cysteine synthesis from peptidyl-cysteine|regulation of peptidyl-S-palmitoyl-L-cysteine formation from peptidyl-cysteine|regulation of peptidyl-S-palmitoyl-L-cysteine biosynthetic process from peptidyl-cysteine|regulation of peptidyl-cysteine S-palmitoylation							mm2	2014-01-29T11:33:09Z					biological_process											owl:Class	
GO:0102472	biolink:NamedThing	eriodictyol 2-hydroxylase activity	Catalysis of the reaction: eriodictyol + NADPH + O2 + 2 H+ <=> 2-hydroxyeriodictyol + NADP + H2O.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-14077|RHEA:57596									molecular_function											owl:Class	
GO:0034146	biolink:NamedThing	toll-like receptor 5 signaling pathway	Any series of molecular signals generated as a consequence of binding to toll-like receptor 5.	tmpzr1t_l9r_go_relaxed.owl	toll-like receptor 5 signalling pathway|TLR5 signaling pathway													biological_process											owl:Class	
GO:0052592	biolink:NamedThing	oxidoreductase activity, acting on CH or CH2 groups, with an iron-sulfur protein as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which a CH2 group acts as a hydrogen or electron donor and reduces an iron-sulfur protein.	tmpzr1t_l9r_go_relaxed.owl	oxidoreductase activity, acting on CH or CH2 groups, with an iron-sulphur protein as acceptor				EC:1.17.7.-									molecular_function											owl:Class	
GO:0015476	biolink:NamedThing	hemaglutinin autotransporter activity	Enables the transfer of hemaglutinin from the periplasm to the external milieu; the hemaglutinin and the porin are the N- and C-terminal regions of the same protein, respectively.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0062060	biolink:NamedThing	NuA4 histone acetyltransferase complex binding	Binding to a NuA4 histone acetyltransferase complex.	tmpzr1t_l9r_go_relaxed.owl								dph	2018-08-31T13:51:45Z					molecular_function											owl:Class	
GO:1902152	biolink:NamedThing	positive regulation of response to DNA integrity checkpoint signaling	Any process that activates or increases the frequency, rate or extent of response to DNA integrity checkpoint signaling.	tmpzr1t_l9r_go_relaxed.owl	activation of response to DNA integrity checkpoint signaling|upregulation of DNA integrity checkpoint effector process|up-regulation of response to signal involved in DNA integrity checkpoint|activation of response to signal involved in DNA integrity checkpoint|up regulation of DNA integrity checkpoint effector process|up regulation of response to signal involved in DNA integrity checkpoint|up regulation of response to DNA integrity checkpoint signaling|positive regulation of DNA integrity checkpoint effector process|up-regulation of response to DNA integrity checkpoint signaling|up-regulation of DNA integrity checkpoint effector process|upregulation of response to DNA integrity checkpoint signaling|positive regulation of response to signal involved in DNA integrity checkpoint|upregulation of response to signal involved in DNA integrity checkpoint|activation of DNA integrity checkpoint effector process							jl	2013-05-21T15:44:31Z					biological_process											owl:Class	
GO:0061728	biolink:NamedThing	GDP-mannose biosynthetic process from mannose	The chemical reactions and pathways resulting in the formation of GDP-mannose from mannose.	tmpzr1t_l9r_go_relaxed.owl								dph	2015-07-24T14:44:04Z					biological_process											owl:Class	
GO:0098718	biolink:NamedThing	serine import across plasma membrane	The directed movement of serine from outside of a cell, across the plasma membrane and into the cytosol.	tmpzr1t_l9r_go_relaxed.owl	serine import into cell							dph	2012-12-06T14:55:29Z			GO:0061491		biological_process											owl:Class	
GO:0031923	biolink:NamedThing	pyridoxine transport	The directed movement of pyridoxine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Pyridoxine, 2-methyl-3-hydroxy-4,5-bis(hydroxymethyl)pyridine, is one of the vitamin B6 compounds. Pyridoxal, pyridoxamine and pyridoxine are collectively known as vitamin B6, and are efficiently converted to the biologically active form of vitamin B6, pyridoxal phosphate.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0102304	biolink:NamedThing	sesquithujene synthase activity	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate(3-) <=> 7-epi-sesquithujene + diphosphoric acid.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-12838|EC:4.2.3.102|RHEA:31991									molecular_function											owl:Class	
GO:0007440	biolink:NamedThing	foregut morphogenesis	The process in which the anatomical structures of the foregut are generated and organized.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0016052	biolink:NamedThing	carbohydrate catabolic process	The chemical reactions and pathways resulting in the breakdown of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y.	tmpzr1t_l9r_go_relaxed.owl	single-organism carbohydrate catabolic process|catabolic carbohydrate metabolism|carbohydrate catabolism|catabolic carbohydrate metabolic process|carbohydrate degradation|carbohydrate breakdown|multicellular organismal carbohydrate catabolic process							jl	2012-10-23T16:34:39Z			GO:0044276|GO:0044724|GO:0006095		biological_process											owl:Class	
GO:1900278	biolink:NamedThing	positive regulation of proteinase activated receptor activity	Any process that activates or increases the frequency, rate or extent of proteinase activated receptor activity.	tmpzr1t_l9r_go_relaxed.owl	activation of proteinase activated receptor activity|up regulation of proteinase activated receptor activity|upregulation of proteinase activated receptor activity|up-regulation of proteinase activated receptor activity							rl	2012-04-04T01:31:37Z					biological_process											owl:Class	
GO:0060637	biolink:NamedThing	positive regulation of lactation by mesenchymal-epithelial cell signaling	The process that increases the rate, frequency, or extent of lactation as a result of the secretion of a signal from the mammary fat and its reception by a mammary epithelial cell.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of lactation by mesenchymal-epithelial cell signalling							dph	2009-05-19T03:39:24Z					biological_process											owl:Class	
GO:0009380	biolink:NamedThing	excinuclease repair complex	Any of the protein complexes formed by the UvrABC excinuclease system, which carries out nucleotide excision repair. Three different complexes are formed by the 3 proteins as they proceed through the excision repair process. First a complex consisting of two A subunits and two B subunits bind DNA and unwind it around the damaged site. Then, the A subunits disassociate leaving behind a stable complex between B subunits and DNA. Now, subunit C binds to this B+DNA complex and causes subunit B to nick the DNA on one side of the complex while subunit C nicks the DNA on the other side of the complex. DNA polymerase I and DNA ligase can then repair the resulting gap.	tmpzr1t_l9r_go_relaxed.owl	excinuclease ABC complex|UvrABC excinuclease complex													cellular_component											owl:Class	
GO:0075228	biolink:NamedThing	positive regulation of encysted zoospore germination	Any process that activates, maintains or increases the frequency, rate or extent of encysted zoospore germination.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of encysted zoospore germination on or near host													biological_process											owl:Class	
GO:0047901	biolink:NamedThing	formyl-CoA hydrolase activity	Catalysis of the reaction: formyl-CoA + H(2)O = CoA + formate + H(+).	tmpzr1t_l9r_go_relaxed.owl	formyl coenzyme A hydrolase activity				RHEA:19741|KEGG_REACTION:R00521|EC:3.1.2.10|MetaCyc:FORMYL-COA-HYDROLASE-RXN									molecular_function											owl:Class	
GO:0042296	biolink:NamedThing	ISG15 transferase activity	Catalysis of the transfer of ISG15 from one protein to another via the reaction X-ISG15 + Y --> Y-ISG15 + X, where both X-ISG15 and Y-ISG15 are covalent linkages.	tmpzr1t_l9r_go_relaxed.owl	ISG15 conjugating enzyme activity				Reactome:R-HSA-5653754									molecular_function											owl:Class	
GO:0075293	biolink:NamedThing	response to host pH environment	Any process that results in a change in state or activity of the symbiont or its cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the pH conditions in or around its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	response of symbiont to host pH environment													biological_process											owl:Class	
GO:0047453	biolink:NamedThing	ATP-dependent NAD(P)H-hydrate dehydratase activity	Catalysis of the reaction: (6S)-6beta-hydroxy-1,4,5,6-tetrahydronicotinamide adenine dinucleotide + ATP = ADP + 3 H(+) + NADH + phosphate.	tmpzr1t_l9r_go_relaxed.owl	(6S)-beta-6-hydroxy-1,4,5,6-tetrahydronicotinamide-adenine-dinucleotide hydro-lyase (ATP-hydrolysing)|ATP-dependent H(4)NAD(P)OH dehydratase activity|reduced nicotinamide adenine dinucleotide hydrate dehydratase activity|ATP-dependent H4NAD(P)OH dehydratase activity|(6S)-beta-6-hydroxy-1,4,5,6-tetrahydronicotinamide-adenine-dinucleotide hydro-lyase(ATP-hydrolysing; NADH-forming)				Reactome:R-HSA-6806967|EC:4.2.1.93|KEGG_REACTION:R00129|RHEA:19017|MetaCyc:4.2.1.93-RXN									molecular_function											owl:Class	
GO:0009095	biolink:NamedThing	aromatic amino acid family biosynthetic process, prephenate pathway	The chemical reactions and pathways resulting in the formation of phenylalanine and tyrosine from other compounds, including chorismate, via the intermediate prephenate.	tmpzr1t_l9r_go_relaxed.owl	aromatic amino acid family biosynthetic process via prephenate|aromatic amino acid family anabolism, prephenate pathway|aromatic amino acid family biosynthetic process via prephenate(2-)|aromatic amino acid family formation, prephenate pathway|aromatic amino acid family synthesis, prephenate pathway													biological_process											owl:Class	
GO:1905118	biolink:NamedThing	positive regulation of ribonucleoside-diphosphate reductase activity	Any process that activates or increases the frequency, rate or extent of ribonucleoside-diphosphate reductase activity.	tmpzr1t_l9r_go_relaxed.owl	activation of class II ribonucleoside-diphosphate reductase activity|up regulation of ribonucleotide diphosphate reductase activity|positive regulation of ribonucleoside 5'-diphosphate reductase activity|positive regulation of adenosylcobalamin-dependent ribonucleotide reductase activity|positive regulation of class III ribonucleotide reductase activity|positive regulation of nucleoside diphosphate reductase activity|upregulation of ribonucleotide diphosphate reductase activity|up-regulation of class II ribonucleoside-diphosphate reductase activity|activation of nucleoside diphosphate reductase activity|up regulation of class I ribonucleotide reductase activity|upregulation of class I ribonucleotide reductase activity|activation of ribonucleoside 5'-diphosphate reductase activity|up-regulation of anaerobic iron-sulfur-dependent ribonucleotide reductase activity|up regulation of class III ribonucleotide reductase activity|upregulation of RNR|up regulation of anaerobic iron-sulfur-dependent ribonucleotide reductase activity|activation of adenosylcobalamin-dependent ribonucleotide reductase activity|up regulation of purine/pyrimidine nucleoside diphosphate reduction|activation of class II ribonucleotide reductase activity|positive regulation of purine/pyrimidine nucleoside diphosphate reduction|positive regulation of class I ribonucleotide reductase activity|up-regulation of adenosylcobalamin-dependent ribonucleotide reductase activity|positive regulation of class II ribonucleoside-diphosphate reductase activity|positive regulation of ribonucleotide diphosphate reductase activity|activation of aerobic non-heme iron-dependent ribonucleotide reductase activity|up-regulation of class III ribonucleotide reductase activity|up-regulation of class II ribonucleotide reductase activity|positive regulation of RNR|up-regulation of ribonucleoside-diphosphate reductase activity|upregulation of class III ribonucleotide reductase activity|up-regulation of ribonucleoside 5'-diphosphate reductase activity|positive regulation of class II ribonucleotide reductase activity|up-regulation of RNR|up-regulation of class I ribonucleotide reductase activity|activation of anaerobic iron-sulfur-dependent ribonucleotide reductase activity|upregulation of anaerobic iron-sulfur-dependent ribonucleotide reductase activity|up regulation of ribonucleoside 5'-diphosphate reductase activity|up-regulation of purine/pyrimidine nucleoside diphosphate reduction|activation of class III ribonucleotide reductase activity|activation of purine/pyrimidine nucleoside diphosphate reduction|upregulation of adenosylcobalamin-dependent ribonucleotide reductase activity|upregulation of ribonucleoside 5'-diphosphate reductase activity|activation of RNR|up regulation of class II ribonucleotide reductase activity|up regulation of aerobic non-heme iron-dependent ribonucleotide reductase activity|up-regulation of aerobic non-heme iron-dependent ribonucleotide reductase activity|positive regulation of aerobic non-heme iron-dependent ribonucleotide reductase activity|upregulation of aerobic non-heme iron-dependent ribonucleotide reductase activity|upregulation of class II ribonucleotide reductase activity|upregulation of class II ribonucleoside-diphosphate reductase activity|upregulation of ribonucleoside-diphosphate reductase activity|activation of ribonucleotide diphosphate reductase activity|up regulation of RNR|up regulation of ribonucleoside-diphosphate reductase activity|up regulation of adenosylcobalamin-dependent ribonucleotide reductase activity|positive regulation of anaerobic iron-sulfur-dependent ribonucleotide reductase activity|activation of ribonucleoside-diphosphate reductase activity|activation of class I ribonucleotide reductase activity|up regulation of nucleoside diphosphate reductase activity|up-regulation of nucleoside diphosphate reductase activity|up-regulation of ribonucleotide diphosphate reductase activity|upregulation of purine/pyrimidine nucleoside diphosphate reduction|upregulation of nucleoside diphosphate reductase activity|up regulation of class II ribonucleoside-diphosphate reductase activity					An example of this is DRE2 in Saccharomyces cerevisiae (UniProt ID P36152) in PMID:24733891 (inferred from mutant phenotype).		bhm	2016-04-08T08:06:35Z					biological_process											owl:Class	
GO:1903244	biolink:NamedThing	positive regulation of cardiac muscle hypertrophy in response to stress	Any process that activates or increases the frequency, rate or extent of cardiac muscle hypertrophy in response to stress.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of cardiac muscle hypertrophy in response to stress|up regulation of cardiac muscle hypertrophy in response to stress|activation of cardiac muscle hypertrophy in response to stress|upregulation of cardiac muscle hypertrophy in response to stress							rl	2014-08-01T16:31:48Z					biological_process											owl:Class	
GO:1902432	biolink:NamedThing	protein localization to division septum	A process in which a protein is transported to, or maintained in, a location within a division septum.	tmpzr1t_l9r_go_relaxed.owl	protein localization in division septum|protein localisation to division septum|protein localisation in division septum							mah	2013-09-30T14:29:51Z					biological_process											owl:Class	
GO:0061385	biolink:NamedThing	fibroblast proliferation involved in heart morphogenesis	The multiplication or reproduction of fibroblasts, resulting in the expansion of a fibroblast population that contributes to the shaping of the heart.	tmpzr1t_l9r_go_relaxed.owl								dph	2011-02-10T01:41:59Z					biological_process											owl:Class	
GO:0034498	biolink:NamedThing	early endosome to Golgi transport	The directed movement of substances from early endosomes to the Golgi.	tmpzr1t_l9r_go_relaxed.owl	PGE to Golgi transport|post-Golgi endosome to Golgi transport													biological_process											owl:Class	
GO:0061206	biolink:NamedThing	mesonephros morphogenesis	The process in which the anatomical structures of the mesonephros are generated and organized.	tmpzr1t_l9r_go_relaxed.owl	Wolffian body morphogenesis							dph	2010-08-17T03:11:10Z					biological_process											owl:Class	
GO:0008011	biolink:NamedThing	structural constituent of pupal chitin-based cuticle	The action of a molecule that contributes to the structural integrity of the chitin-based cuticle of a pupa. An example of this is found in Drosophila melanogaster.	tmpzr1t_l9r_go_relaxed.owl	structural constituent of pupal cuticle													molecular_function											owl:Class	
GO:0010877	biolink:NamedThing	lipid transport involved in lipid storage	The directed movement of lipids into cells that is part of their accumulation and maintenance.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0004765	biolink:NamedThing	shikimate kinase activity	Catalysis of the reaction: ATP + shikimate = 3-phosphoshikimate + ADP + 2 H(+).	tmpzr1t_l9r_go_relaxed.owl	shikimate kinase II|shikimate kinase (phosphorylating)|ATP:shikimate 3-phosphotransferase activity				EC:2.7.1.71|RHEA:13121|KEGG_REACTION:R02412|MetaCyc:SHIKIMATE-KINASE-RXN									molecular_function											owl:Class	
GO:1900895	biolink:NamedThing	positive regulation of tridecane metabolic process	Any process that activates or increases the frequency, rate or extent of tridecane metabolic process.	tmpzr1t_l9r_go_relaxed.owl	activation of tridecane metabolism|up-regulation of tridecane metabolism|positive regulation of tridecane metabolism|up regulation of tridecane metabolism|upregulation of tridecane metabolic process|up-regulation of tridecane metabolic process|activation of tridecane metabolic process|up regulation of tridecane metabolic process|upregulation of tridecane metabolism							tt	2012-06-13T03:15:11Z					biological_process											owl:Class	
GO:0010889	biolink:NamedThing	regulation of sequestering of triglyceride	Any process that modulates the rate, frequency or extent of sequestering of triglyceride. Triglyceride sequestration is the process of binding or confining any triester of glycerol such that it is separated from other components of a biological system.	tmpzr1t_l9r_go_relaxed.owl	regulation of triacylglycerol sequestration|regulation of sequestering of triacylglycerol													biological_process											owl:Class	
GO:0140161	biolink:NamedThing	monocarboxylate:sodium symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: monocarboxylate(out) + Na+(out) = monocarboxylate(in) + Na+(in).	tmpzr1t_l9r_go_relaxed.owl								pg	2018-02-05T10:33:55Z					molecular_function											owl:Class	
GO:0097491	biolink:NamedThing	sympathetic neuron projection guidance	The process in which the migration of a sympathetic neuron projection is directed to a specific target site in response to a combination of attractive and repulsive cues.	tmpzr1t_l9r_go_relaxed.owl	sympathetic neurite guidance|sympathetic neuron process guidance|sympathetic neuronal cell projection guidance|sympathetic neuron protrusion guidance							pr	2013-07-10T11:49:21Z					biological_process											owl:Class	
GO:0102878	biolink:NamedThing	(+)-alpha-barbatene synthase activity	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate <=> (+)-alpha-barbatene + diphosphoric acid.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-8417|RHEA:29499|EC:4.2.3.69									molecular_function											owl:Class	
GO:1990518	biolink:NamedThing	single-stranded 3'-5' DNA helicase activity	Catalysis of the reaction: ATP + H2O = ADP + phosphate, in the presence of single-stranded DNA; drives the unwinding of the DNA helix in the direction 3' to 5'.	tmpzr1t_l9r_go_relaxed.owl								al	2014-10-22T10:17:40Z					molecular_function											owl:Class	
GO:0043138	biolink:NamedThing	3'-5' DNA helicase activity	Unwinding a DNA helix in the direction 5' to 3', driven by ATP hydrolysis.	tmpzr1t_l9r_go_relaxed.owl	ATP-dependent 3'-5' DNA helicase activity|ATP-dependent 3' to 5' DNA helicase activity|3' to 5' DNA helicase activity				Reactome:R-HSA-9613497|Reactome:R-HSA-174438|Reactome:R-HSA-9613498|Reactome:R-HSA-9613490|Reactome:R-HSA-75949|Reactome:R-HSA-9613494|Reactome:R-HSA-167097|Reactome:R-HSA-9684118							GO:0043140		molecular_function											owl:Class	
GO:0097384	biolink:NamedThing	cellular lipid biosynthetic process	The chemical reactions and pathways resulting in the formation of lipids, as carried out by individual cells.	tmpzr1t_l9r_go_relaxed.owl	cellular lipid anabolism|cellular lipid synthesis|cellular lipid biosynthesis|cellular lipid formation							pr	2012-10-16T16:47:09Z					biological_process											owl:Class	
GO:0045516	biolink:NamedThing	interleukin-19 receptor binding	Binding to an interleukin-19 receptor.	tmpzr1t_l9r_go_relaxed.owl	IL-19|interleukin-19 receptor ligand													molecular_function											owl:Class	
GO:1904918	biolink:NamedThing	transmembrane L-histidine transport from lysosomal lumen to cytosol	The directed movement of L-histidine from the lysosomal lumen across the lysosomal membrane and into the cytosol.	tmpzr1t_l9r_go_relaxed.owl								kmv	2016-01-21T16:27:55Z					biological_process											owl:Class	
GO:0045269	biolink:NamedThing	proton-transporting ATP synthase, central stalk	One of two stalks that connect the catalytic core of the hydrogen-transporting ATP synthase to the membrane-associated Fo proteins; rotates within the catalytic core during catalysis.	tmpzr1t_l9r_go_relaxed.owl	hydrogen-transporting ATP synthase, central stalk													cellular_component											owl:Class	
GO:0009751	biolink:NamedThing	response to salicylic acid	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a salicylic acid stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to salicylic acid stimulus|response to salicylate													biological_process											owl:Class	
GO:0098743	biolink:NamedThing	cell aggregation	The clustering together and adhesion of initially separate cells to form an aggregate.  Examples include the clustering of unicellular organisms or blood cells in suspension and the condensation of mesenchymal cells during cartilage formation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0035698	biolink:NamedThing	CD8-positive, alpha-beta cytotoxic T cell extravasation	The migration of a CD8-positive, alpha-beta cytotoxic T cell from the blood vessels into the surrounding tissue.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-02-28T03:09:53Z					biological_process											owl:Class	
GO:0004417	biolink:NamedThing	hydroxyethylthiazole kinase activity	Catalysis of the reaction: 5-(2-hydroxyethyl)-4-methylthiazole + ATP = 4-methyl-5-(2-phosphoethyl)-thiazole + ADP + 2 H(+).	tmpzr1t_l9r_go_relaxed.owl	4-methyl-5-(beta-hydroxyethyl)thiazole kinase activity|hydroxyethylthiazole kinase (phosphorylating)|ATP:4-methyl-5-(2-hydroxyethyl)thiazole 2-phosphotransferase activity				KEGG_REACTION:R04448|EC:2.7.1.50|MetaCyc:THIAZOLSYN3-RXN|RHEA:24212									molecular_function											owl:Class	
GO:0062059	biolink:NamedThing	FACT complex binding	Binding to a FACT complex.	tmpzr1t_l9r_go_relaxed.owl								dph	2018-08-31T13:49:30Z					molecular_function											owl:Class	
GO:0043930	biolink:NamedThing	primary ovarian follicle growth involved in primary follicle stage	Increase in size of primary follicles including oocyte growth and granulosa and/or theca cell proliferation until more than one layer of granulosa cells is present (preantral follicle) as part of the primary follicle stage of oogenesis.	tmpzr1t_l9r_go_relaxed.owl	primary ovarian follicle growth during primary follicle stage													biological_process											owl:Class	
GO:0050123	biolink:NamedThing	N-acylmannosamine 1-dehydrogenase activity	Catalysis of the reaction: N-acyl-D-mannosamine + NAD(+) = N-acyl-D-mannosaminolactone + H(+) + NADH.	tmpzr1t_l9r_go_relaxed.owl	N-acyl-D-mannosamine:NAD+ 1-oxidoreductase activity|N-acetyl-D-mannosamine dehydrogenase activity|N-acylmannosamine dehydrogenase activity|N-acyl-D-mannosamine dehydrogenase activity				MetaCyc:N-ACYLMANNOSAMINE-1-DEHYDROGENASE-RXN|KEGG_REACTION:R02651|EC:1.1.1.233|RHEA:11540									molecular_function											owl:Class	
GO:0006610	biolink:NamedThing	ribosomal protein import into nucleus	The directed movement of a ribosomal protein from the cytoplasm into the nucleus, across the nuclear membrane. At least some ribosomal proteins, including rpl12, uses the importin 11 pathway as a major route into the nucleus.	tmpzr1t_l9r_go_relaxed.owl	ribosomal protein transport from cytoplasm to nucleus|ribosomal protein-nucleus import|ribosomal protein import into cell nucleus	https://github.com/geneontology/go-annotation/issues/1700				Ribosomal protein rpl12 uses a different import pathway, which is why it has a separate GO term.								biological_process											owl:Class	
GO:1990040	biolink:NamedThing	sub-surface cisterna	Specialization of the hypolemmal cisterna consisting of either single profiles or closely apposed stacks of endoplasmic reticulum in which the lumen is obliterated, lying 10-20 nm beneath the plasma membrane.	tmpzr1t_l9r_go_relaxed.owl	sub-surface cisternae				NIF_Subcellular:sao128470897			pr	2013-02-11T15:10:47Z					cellular_component											owl:Class	
GO:1990039	biolink:NamedThing	hypolemmal cisterna	Specialized part of the smooth endoplasmic reticulum that closely underlies the plasma membrane, usually within 60 nm or closer.	tmpzr1t_l9r_go_relaxed.owl	hypolemmal cisternae				NIF_Subcellular:sao1634374950			pr	2013-02-11T15:04:56Z					cellular_component											owl:Class	
GO:0052652	biolink:NamedThing	cyclic purine nucleotide metabolic process	The chemical reactions and pathways involving a cyclic nucleotide, a nucleotide in which the phosphate group is in diester linkage to two positions on the sugar residue and the base is a purine.	tmpzr1t_l9r_go_relaxed.owl	cyclic purine nucleotide metabolism								2010-09-23T11:15:59Z					biological_process											owl:Class	
GO:0009204	biolink:NamedThing	deoxyribonucleoside triphosphate catabolic process	The chemical reactions and pathways resulting in the breakdown of a deoxyribonucleoside triphosphate, a compound consisting of a nucleobase linked to a deoxyribose sugar esterified with triphosphate on the sugar.	tmpzr1t_l9r_go_relaxed.owl	deoxyribonucleoside triphosphate degradation|deoxyribonucleoside triphosphate catabolism|deoxyribonucleoside triphosphate breakdown													biological_process											owl:Class	
GO:0061828	biolink:NamedThing	apical tubulobulbar complex	Actin-based structures involved in establishing close contact between mature spermatids and Sertoli cells at the luminal end of the Sertoli cell.	tmpzr1t_l9r_go_relaxed.owl	apical TBC							dph	2017-01-15T10:41:00Z					cellular_component											owl:Class	
GO:0036284	biolink:NamedThing	tubulobulbar complex	Actin-based structures involved in establishing close contact between Sertoli-Sertoli cells or Sertoli-spermatids in the seminiferous tubules of the testes.	tmpzr1t_l9r_go_relaxed.owl	TBC							bf	2012-07-16T10:26:35Z					cellular_component											owl:Class	
GO:0001402	biolink:NamedThing	signal transduction involved in filamentous growth	Relaying of environmental signals promoting filamentous growth.	tmpzr1t_l9r_go_relaxed.owl	MAPKKK cascade (pseudohyphal growth)|signal transduction during filamentous growth													biological_process											owl:Class	
GO:0002079	biolink:NamedThing	inner acrosomal membrane	The acrosomal membrane region that underlies the acrosomal vesicle and is located toward the sperm nucleus. This region is responsible for molecular interactions allowing the sperm to penetrate the zona pellucida and fuses with the egg plasma membrane.	tmpzr1t_l9r_go_relaxed.owl						Note that this term is not a descendant of 'organelle inner membrane ; GO:0019866' because the outer acrosomal membrane is a portion of the acrosomal membrane; the latter is a single lipid bilayer.								cellular_component											owl:Class	
GO:0097731	biolink:NamedThing	9+0 non-motile cilium	A non-motile cilium where the axoneme has a ring of nine outer microtubule doublets but no central microtubules (and is therefore called a 9+0 axoneme).	tmpzr1t_l9r_go_relaxed.owl	9+0 immotile cilium|primary cilium|non-motile 9+0 cilium					This type of cilia may be present in solitary (authentic primary cilia in many cell types) or in multiple copies (e.g. in Grueneberg ganglion neurons).		pr	2016-09-29T14:05:03Z					cellular_component											owl:Class	
GO:0050007	biolink:NamedThing	isonocardicin synthase activity	Catalysis of the reaction: S-adenosyl-L-methionine(1+) + nocardicin E = S-methyl-5'-thioadenosine + H(+) + isonocardicin A.	tmpzr1t_l9r_go_relaxed.owl	nocardicin aminocarboxypropyltransferase activity|S-adenosyl-L-methionine:nocardicin-E 3-amino-3-carboxypropyltransferase activity				KEGG_REACTION:R03072|EC:2.5.1.38|MetaCyc:ISONOCARDICIN-SYNTHASE-RXN|RHEA:19845									molecular_function											owl:Class	
GO:0010943	biolink:NamedThing	NADPH pyrophosphatase activity	Catalysis of the reaction: NADPH + H2O = NMNH + ADP.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0044734	biolink:NamedThing	envenomation resulting in positive regulation of acid-sensing ion channel activity in other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with a resultant positive regulation in the activity of an acid-sensing ion channel (ASIC) in the bitten organism.	tmpzr1t_l9r_go_relaxed.owl	envenomation resulting in positive regulation of ASIC channel activity in other organism							jl	2012-11-06T16:02:01Z					biological_process											owl:Class	
GO:1904563	biolink:NamedThing	phosphatidylinositol 5-phosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of phosphatidylinositol 5-phosphate.	tmpzr1t_l9r_go_relaxed.owl	phosphatidylinositol 5-phosphate anabolism|phosphatidylinositol 5-phosphate biosynthesis|phosphatidylinositol 5-phosphate formation|phosphatidylinositol 5-phosphate synthesis							dph	2015-08-18T16:21:50Z					biological_process											owl:Class	
GO:0035637	biolink:NamedThing	multicellular organismal signaling	The transfer of information occurring at the level of a multicellular organism.	tmpzr1t_l9r_go_relaxed.owl	multicellular organismal signalling							bf	2011-01-14T10:13:50Z					biological_process											owl:Class	
GO:0052722	biolink:NamedThing	fatty acid in-chain hydroxylase activity	Catalysis of the reaction: fatty acid + O2 + 2 NADPH + H+ = fatty acid with in-chain hydroxy group + 2 NADP+ + H2O.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-12186|RHEA:45084			ai	2011-08-15T01:41:07Z					molecular_function											owl:Class	
GO:0005503	biolink:NamedThing	all-trans retinal binding	Binding to all-trans retinal, a compound that plays an important role in the visual process in most vertebrates. All-trans retinal (trans r., visual yellow) results from the bleaching of rhodopsin by light, in which the 11-cis form is converted to the all-trans form. Retinal is one of the forms of vitamin A.	tmpzr1t_l9r_go_relaxed.owl	visual yellow binding|trans retinal binding|all-trans retinaldehyde binding|vitamin A binding|xanthopsin													molecular_function											owl:Class	
GO:0016918	biolink:NamedThing	retinal binding	Binding to retinal, one of the forms of vitamin A. Retinal plays an important role in the visual process in most vertebrates, combining with opsins to form visual pigments in the retina.	tmpzr1t_l9r_go_relaxed.owl	violet-sensitive opsin|retinaldehyde binding|red-sensitive opsin|UV-sensitive opsin|opsin|long-wave-sensitive opsin|short-wave-sensitive opsin|blue-sensitive opsin|green-sensitive opsin|vitamin A binding													molecular_function											owl:Class	
GO:1902070	biolink:NamedThing	positive regulation of sphingolipid mediated signaling pathway	Any process that activates or increases the frequency, rate or extent of sphingolipid signaling.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of sphingolipid signaling pathway|upregulation of sphingolipid mediated signaling pathway|positive regulation of sphingolipid signaling pathway|activation of sphingolipid signaling pathway|up regulation of sphingolipid signaling pathway|upregulation of sphingolipid signaling pathway|activation of sphingolipid mediated signaling pathway|up-regulation of sphingolipid mediated signaling pathway|up regulation of sphingolipid mediated signaling pathway							bf	2013-04-18T13:24:56Z					biological_process											owl:Class	
GO:1902838	biolink:NamedThing	regulation of nuclear migration along microtubule	Any process that modulates the frequency, rate or extent of nuclear migration along microtubule.	tmpzr1t_l9r_go_relaxed.owl	regulation of microtubule-mediated nuclear migration|regulation of nucleus migration|regulation of microtubule-dependent nucleus positioning|regulation of microtubule cytoskeleton-dependent nuclear positioning|regulation of transport of nucleus, microtubule-mediated|regulation of microtubule-dependent nuclear positioning|regulation of nuclear migration, microtubule-mediated|regulation of transport of nucleus by microtubules|regulation of microtubule cytoskeleton-dependent nucleus positioning|regulation of nuclear movement, microtubule-mediated							vw	2014-04-01T13:50:23Z					biological_process											owl:Class	
GO:0070223	biolink:NamedThing	sulfide oxidation, using sulfur dioxygenase	A sulfide oxidation process that proceeds via the reaction catalyzed by sulfur dioxygenase.	tmpzr1t_l9r_go_relaxed.owl	sulphide oxidation, using sulfur dioxygenase				MetaCyc:PWY-5285									biological_process											owl:Class	
GO:0000497	biolink:NamedThing	DNA template activity	Binding to nucleic acid via hydrogen bonds between the bases of a gene product molecule and the bases of a target DNA molecule.	tmpzr1t_l9r_go_relaxed.owl	base pairing with DNA					Note that with respect to annotation, "base pairing" and its child terms are intended to be used to annotate the activity of gene products composed of nucleic acid, presumably RNA, to interact with DNA molecules via base pairing. Internal base pairing with itself is considered part of the secondary structure of the molecule and is not within the scope of GO function.								molecular_function											owl:Class	
GO:0040009	biolink:NamedThing	regulation of growth rate	Any process that modulates the rate of growth of all or part of an organism.	tmpzr1t_l9r_go_relaxed.owl						Note that this term and its definition depart from the usual conventions for GO 'regulation' process terms; regulation of rate is not usually distinguished from regulation of extent or frequency, but it makes sense to do so for growth regulation.								biological_process											owl:Class	
GO:1990516	biolink:NamedThing	ribonucleotide excision repair	The pathway by which a ribonucleotide is removed from DNA and replaced by a deoxyribonucleotide. The ribonucleotide is incised by RNase H2, and further excised by an endonuclease. The resulting 1 nt gap is then repaired by DNA polymerase and DNA ligase.	tmpzr1t_l9r_go_relaxed.owl								al	2014-10-14T12:24:37Z					biological_process											owl:Class	
GO:0052577	biolink:NamedThing	germacrene-D synthase activity	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = (-)-germacrene D + diphosphate.	tmpzr1t_l9r_go_relaxed.owl	2-trans,6-trans-farnesyl-diphosphate diphosphate-lyase [(-)-Germacrene D-forming] activity				EC:4.2.3.22|KEGG_REACTION:R07648|MetaCyc:RXN-8562|RHEA:12016			ai	2010-08-09T01:39:02Z					molecular_function											owl:Class	
GO:0102400	biolink:NamedThing	dTDP-3-amino-4-oxo-2,3,6-trideoxy-alpha-D-glucose N,N-dimethyltransferase activity	Catalysis of the reaction: 2 S-adenosyl-L-methionine  + dTDP-3-amino-4-dehydro-2,3,6-trideoxy-alpha-D-glucose <=> 2 S-adenosyl-L-homocysteine  + dTDP-3-N,N-dimethylamino-4-oxo-2,3,6-trideoxy-alpha-D-glucose + 2 H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-13667									molecular_function											owl:Class	
GO:0102933	biolink:NamedThing	GDP-4-dehydro-6-deoxy-D-mannose-4-aminotransferase activity	Catalysis of the reaction: GDP-4-amino-4,6-dideoxy-alpha-D-mannose + 2-oxoglutarate = GDP-4-dehydro-6-deoxy-alpha-D-mannose + L-glutamate.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-8953|RHEA:36779|EC:2.6.1.102									molecular_function											owl:Class	
GO:0010100	biolink:NamedThing	negative regulation of photomorphogenesis	Any process that stops, reduces or prevents photomorphogenesis.	tmpzr1t_l9r_go_relaxed.owl	down regulation of photomorphogenesis|down-regulation of photomorphogenesis|inhibition of photomorphogenesis|downregulation of photomorphogenesis													biological_process											owl:Class	
GO:0002493	biolink:NamedThing	lipid antigen assembly with MHC class Ib protein complex	The binding of a lipid antigen to the antigen binding groove of an MHC class Ib protein complex. Class Ib here refers to non-classical class I molecules, such as those of the CD1 gene family.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0045325	biolink:NamedThing	peptidyl-tryptophan hydroxylation	The hydroxylation of peptidyl-tryptophan, to form peptidyl-L-3-hydroxytryptophan.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0322									biological_process											owl:Class	
GO:0042711	biolink:NamedThing	maternal behavior	Female behaviors associated with the care and rearing of offspring.	tmpzr1t_l9r_go_relaxed.owl	maternal behaviour													biological_process											owl:Class	
GO:0060746	biolink:NamedThing	parental behavior	A reproductive behavior in which a parent cares for and rears offspring.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-06-22T09:05:26Z					biological_process											owl:Class	
GO:1990213	biolink:NamedThing	negative regulation by symbiont of salicylic acid levels in host	Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of salicylic acid levels in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl								ml	2013-10-09T19:06:19Z					biological_process											owl:Class	
GO:0050135	biolink:NamedThing	NAD(P)+ nucleosidase activity	Catalysis of the reaction: NAD(P)+ + H2O = ADP-ribose(P) + nicotinamide.	tmpzr1t_l9r_go_relaxed.owl	nicotinamide adenine dinucleotide (phosphate) glycohydrolase activity|nicotinamide adenine dinucleotide (phosphate) nucleosidase activity|NAD(P)+ glycohydrolase activity|NAD(P) nucleosidase activity|NAD(P)ase activity|triphosphopyridine nucleotidase activity|NAD(P)(+) nucleosidase activity				MetaCyc:NADP+-NUCLEOSIDASE-RXN|EC:3.2.2.6									molecular_function											owl:Class	
GO:0051794	biolink:NamedThing	regulation of timing of catagen	Any process that modulates the frequency, rate or extent of timing of catagen, the regression phase of the hair cycle.	tmpzr1t_l9r_go_relaxed.owl	regulation of catagen													biological_process											owl:Class	
GO:0030254	biolink:NamedThing	protein secretion by the type III secretion system	The process in which proteins are transferred into the extracellular milieu or directly into host cells by the bacterial type III secretion system; secretion occurs in a continuous process without the distinct presence of periplasmic intermediates and does not involve proteolytic processing of secreted proteins.	tmpzr1t_l9r_go_relaxed.owl	type III protein secretion system|protein secretion by the T3S|protein secretion by the TTSS|protein secretion by the type III protein secretion system|protein secretion by the T3SS					Note that this term represents an activity and not a cellular structure. Consider also annotating to the cellular component term 'type III protein secretion system complex ; GO:0030257'. Note that this term is used for annotation of proteins that compose the secretion complex but not the proteins being secreted.								biological_process											owl:Class	
GO:0030633	biolink:NamedThing	D-alanine family amino acid catabolic process	The chemical reactions and pathways resulting in the breakdown of D-alanine and related amino acids.	tmpzr1t_l9r_go_relaxed.owl	D-alanine family amino acid degradation|D-alanine family amino acid breakdown|D-alanine family amino acid catabolism													biological_process											owl:Class	
GO:0071983	biolink:NamedThing	exit from reproductive diapause	The dormancy process that results in exit from reproductive diapause. Reproductive diapause is a form of diapause where the organism itself will remain fully active, including feeding and other routine activities, but the reproductive organs experience a tissue-specific reduction in metabolism, with characteristic triggering and releasing stimuli.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-10-21T04:48:12Z					biological_process											owl:Class	
GO:0003392	biolink:NamedThing	cell adhesion involved in retrograde extension	The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix that contributes to the process of retrograde extension.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-12-09T09:32:06Z					biological_process											owl:Class	
GO:1905470	biolink:NamedThing	positive regulation of clathrin-coated pit assembly	Any process that activates or increases the frequency, rate or extent of clathrin-coated pit assembly.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of coated pit assembly|up-regulation of coated pit formation|positive regulation of coated pit assembly|up regulation of clathrin-coated pit assembly|upregulation of coated pit formation|up-regulation of clathrin-coated pit assembly|activation of clathrin-coated pit assembly|positive regulation of clathrin-coated pit formation|up regulation of coated pit formation|positive regulation of coated pit formation|up regulation of clathrin-coated pit formation|up-regulation of clathrin-coated pit formation|up regulation of coated pit assembly|upregulation of clathrin-coated pit assembly|activation of coated pit formation|upregulation of clathrin-coated pit formation|activation of coated pit assembly|upregulation of coated pit assembly|activation of clathrin-coated pit formation							bf	2016-09-20T10:04:53Z					biological_process											owl:Class	
GO:0072649	biolink:NamedThing	interferon-kappa production	The appearance of interferon-kappa due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	tmpzr1t_l9r_go_relaxed.owl	IFN-kappa production|interferon-kappa secretion|IFNK production					Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.						GO:0072650		biological_process											owl:Class	
GO:0032606	biolink:NamedThing	type I interferon production	The appearance of type I interferon due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families.	tmpzr1t_l9r_go_relaxed.owl	type I interferon secretion|type I interferon biosynthetic process|interferon type I production|type I IFN production					Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.						GO:0072641|GO:0045351		biological_process											owl:Class	
GO:0005274	biolink:NamedThing	allantoin:proton symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: allantoin(out) + H+(out) = allantoin(in) + H+(in) by secondary active transport.	tmpzr1t_l9r_go_relaxed.owl	allantoin/allantoate transporter|allantoin uptake transmembrane transporter activity|allantoin permease activity											GO:0015206		molecular_function											owl:Class	
GO:0061473	biolink:NamedThing	murein tripeptide carboxypeptidase activity	Catalysis of the reaction L-Ala-gamma-D-Glu-meso-Dap (murein tripeptide) + H2O = L-Ala-gamma-D-Glu + meso-diaminopimelate.	tmpzr1t_l9r_go_relaxed.owl								dph	2012-11-06T12:23:39Z					molecular_function											owl:Class	
GO:0004181	biolink:NamedThing	metallocarboxypeptidase activity	Catalysis of the hydrolysis of a single C-terminal amino acid residue from a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/19681			Reactome:R-HSA-8955712|Reactome:R-HSA-2022378|Reactome:R-HSA-8866105|Reactome:R-HSA-2022379|Reactome:R-HSA-2028294|Reactome:R-HSA-9023159|Reactome:R-HSA-8852809|Reactome:R-HSA-9023163|EC:3.4.17.-									molecular_function											owl:Class	
GO:0140048	biolink:NamedThing	manganese ion export across plasma membrane	The directed movement of manganese ions from inside of a cell, across the plasma membrane and into the extracellular region.	tmpzr1t_l9r_go_relaxed.owl	manganese ion export from cell							pg	2017-06-23T14:25:00Z					biological_process											owl:Class	
GO:1902500	biolink:NamedThing	vacuolar HOPS complex	Any HOPS complex that is part of a vacuolar membrane.	tmpzr1t_l9r_go_relaxed.owl	vacuolar membrane HOPS complex							tb	2013-11-14T00:09:50Z					cellular_component											owl:Class	
GO:0097509	biolink:NamedThing	oxanine DNA N-glycosylase activity	DNA N-glycosylase activity acting on deaminated guanine where the resulting base (oxanine) is generated by NO- or HNO2-induced nitrosative deamination.	tmpzr1t_l9r_go_relaxed.owl	oxanine-DNA glycosylase activity							pr	2013-09-26T16:03:58Z					molecular_function											owl:Class	
GO:0002448	biolink:NamedThing	mast cell mediated immunity	Any process involved in the carrying out of an immune response by a mast cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0061131	biolink:NamedThing	pancreas field specification	The process in which a specific region of the gut is delineated into the area in which the pancreas will develop.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-05-17T09:39:49Z					biological_process											owl:Class	
GO:0008980	biolink:NamedThing	propionate kinase activity	Catalysis of the reaction: ATP + propanoate = ADP + propanoyl phosphate.	tmpzr1t_l9r_go_relaxed.owl	PduW|ATP:propanoate phosphotransferase activity|TdcD|propanoate kinase activity				EC:2.7.2.15|RHEA:23148									molecular_function											owl:Class	
GO:0050459	biolink:NamedThing	ethanolamine-phosphate phospho-lyase activity	Catalysis of the reaction: H(2)O + phosphoethanolamine = acetaldehyde + NH(4)(+) + phosphate.	tmpzr1t_l9r_go_relaxed.owl	O-phosphoethanolamine-phospholyase activity|amino alcohol O-phosphate phospholyase activity|ethanolamine-phosphate phospho-lyase (deaminating)|ethanolamine-phosphate phospho-lyase (deaminating; acetaldehyde-forming)|O-phosphorylethanol-amine phospho-lyase activity				EC:4.2.3.2|MetaCyc:ETHANOLAMINE-PHOSPHATE-PHOSPHO-LYASE-RXN|RHEA:17889|Reactome:R-HSA-5696415|KEGG_REACTION:R00748									molecular_function											owl:Class	
GO:0043661	biolink:NamedThing	peribacteroid membrane	A membrane that surrounds one or more bacteroids (such as nitrogen-fixing bacteroids within legume root nodule cells).	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:1905009	biolink:NamedThing	negative regulation of L-lysine import across plasma membrane	Any process that stops, prevents or reduces the frequency, rate or extent of L-lysine import into cell.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of L-lysine import into cell|downregulation of L-lysine import into cell|negative regulation of lysine import|negative regulation of lysine uptake|down regulation of L-lysine import into cell|down-regulation of L-lysine import into cell|inhibition of L-lysine import into cell							sl	2016-03-02T00:15:57Z			GO:0010806		biological_process											owl:Class	
GO:0021798	biolink:NamedThing	forebrain dorsal/ventral pattern formation	The formation of specific regional progenitor domains along the dorsal-ventral axis in the developing forebrain.	tmpzr1t_l9r_go_relaxed.owl	forebrain dorsoventral pattern formation|forebrain dorsal-ventral pattern formation													biological_process											owl:Class	
GO:0070091	biolink:NamedThing	glucagon secretion	The regulated release of glucagon from secretory granules in the A (alpha) cells of the pancreas (islets of Langerhans).	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0035798	biolink:NamedThing	2-alkenal reductase (NADP+) activity	Catalysis of the reaction: n-alkanal + NADP+ = alk-2-enal + NADPH + H+.	tmpzr1t_l9r_go_relaxed.owl	NADPH:2-alkenal alpha,beta-hydrogenase activity							bf	2011-04-14T01:11:07Z					molecular_function											owl:Class	
GO:0032440	biolink:NamedThing	2-alkenal reductase [NAD(P)+] activity	Catalysis of the reaction: n-alkanal + NAD(P)+ = alk-2-enal + NAD(P)H + H+.	tmpzr1t_l9r_go_relaxed.owl	NAD(P)H-dependent alkenal/one oxidoreductase activity|n-alkanal:NAD(P)+ 2-oxidoreductase activity				EC:1.3.1.74									molecular_function											owl:Class	
GO:0018302	biolink:NamedThing	iron incorporation into iron-sulfur cluster via tris-L-cysteinyl-L-N1'-histidino tetrairon tetrasulfide	The incorporation of iron into a 4Fe-4S iron-sulfur cluster via tris-L-cysteinyl-L-N1'-histidino tetrairon tetrasulfide.	tmpzr1t_l9r_go_relaxed.owl	iron incorporation into iron-sulphur cluster via tris-L-cysteinyl-L-N1'-histidino tetrairon tetrasulphide				RESID:AA0284									biological_process											owl:Class	
GO:0010181	biolink:NamedThing	FMN binding	Binding to flavin mono nucleotide. Flavin mono nucleotide (FMN) is the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes.	tmpzr1t_l9r_go_relaxed.owl	flavin mononucleotide binding													molecular_function											owl:Class	
GO:0002582	biolink:NamedThing	positive regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II	Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of antigen (peptide or polysaccharide) via MHC class II.	tmpzr1t_l9r_go_relaxed.owl	activation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II|up-regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II|upregulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II|up regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II|positive regulation of peptide or polysaccharide antigen processing and presentation via MHC class II|stimulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II													biological_process											owl:Class	
GO:0016232	biolink:NamedThing	HNK-1 sulfotransferase activity	Catalysis of the synthesis of the HKK-1 carbohydrate epitope; adds a sulfate group to a precursor, GlcA-beta-(1->3)-Gal-beta-(1->4)-GlcNAc-beta-(1->R), forming sulfo-3GlcA-beta-(1->3)-Gal-beta-(1->4)-GlcNAc-beta-(1->R).	tmpzr1t_l9r_go_relaxed.owl	HNK-1 sulphotransferase activity				Reactome:R-HSA-6786048									molecular_function											owl:Class	
GO:0018699	biolink:NamedThing	1,1,1-trichloroethane reductive dehalogenase activity	Catalysis of the reaction: 1,1,1-trichloroethane + 2 H+ + 2 e- = 1,1-dichloroethane + HCl.	tmpzr1t_l9r_go_relaxed.owl					EC:1.97.1.-|UM-BBD_reactionID:r1007									molecular_function											owl:Class	
GO:0071810	biolink:NamedThing	regulation of fever generation by regulation of prostaglandin secretion	Any process that modulates the rate or extent of fever generation via regulation of the frequency, rate or extent of the regulated release of a prostaglandin from a cell.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-09-03T05:09:27Z					biological_process											owl:Class	
GO:0035016	biolink:NamedThing	elongation of arista lateral	The increase in length of the aristal laterals. The arista is the terminal segment of the antenna and consists of a central core and a series of lateral extensions.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0045851	biolink:NamedThing	pH reduction	Any process that reduces the internal pH of an organism, part of an organism or a cell, measured by the concentration of the hydrogen ion.	tmpzr1t_l9r_go_relaxed.owl	acidification													biological_process											owl:Class	
GO:0080149	biolink:NamedThing	sucrose induced translational repression	Any process that stops, prevents or reduces the rate of translation as a result of increase in sucrose level.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of translation in response to sucrose							dhl	2010-03-26T04:13:15Z					biological_process											owl:Class	
GO:0099508	biolink:NamedThing	voltage-gated ion channel activity involved in regulation of presynaptic membrane potential	Voltage-gated ion channel activity, occurring in the presynaptic membrane, involved in regulation of presynaptic membrane potential. This is a key step in synaptic transmission, following the arrival of an action potential at the synapse.	tmpzr1t_l9r_go_relaxed.owl	voltage-dependent ion channel activity involved in regulation of pre-synaptic membrane potential|voltage gated ion channel activity involved in regulation of presynaptic membrane potential|voltage-dependent ion channel activity involved in regulation of presynaptic membrane potential|voltage-gated ion channel activity involved in regulation of pre-synaptic membrane potential													molecular_function											owl:Class	
GO:0102266	biolink:NamedThing	tRNA-dihydrouridine20a synthase activity	Catalysis of the reaction: a 5,6-dihydrouracil20a in tRNA + NAD(P) <=> H+ + a uracil20a in tRNA + NAD(P)H.	tmpzr1t_l9r_go_relaxed.owl					EC:1.3.1.90|MetaCyc:RXN-12475									molecular_function											owl:Class	
GO:0004493	biolink:NamedThing	methylmalonyl-CoA epimerase activity	Catalysis of the reaction: (R)-methylmalonyl-CoA = (S)-methylmalonyl-CoA.	tmpzr1t_l9r_go_relaxed.owl	methylmalonyl coenzyme A racemase activity|methylmalonyl-CoA racemase activity|DL-methylmalonyl-CoA racemase activity|methylmalonyl-CoA 2-epimerase activity|2-methyl-3-oxopropanoyl-CoA 2-epimerase activity				RHEA:20553|MetaCyc:METHYLMALONYL-COA-EPIM-RXN|EC:5.1.99.1|Reactome:R-HSA-71020|KEGG_REACTION:R02765									molecular_function											owl:Class	
GO:0102328	biolink:NamedThing	3-oxoacid decarboxylase activity	Catalysis of the reaction: H+ + a 3-oxoacid = carbon dioxide + a methylketone.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-13248									molecular_function											owl:Class	
GO:0000832	biolink:NamedThing	inositol hexakisphosphate 5-kinase activity	Catalysis of the reaction: ATP + 1D-myo-inositol 1,2,3,4,5,6-hexakisphosphate = ADP + 5-diphospho-1D-myo-inositol (1,2,3,4,6)pentakisphosphate.	tmpzr1t_l9r_go_relaxed.owl	ATP:1D-myo-inositol-hexakisphosphate 5-phosphotransferase activity				RHEA:12793|EC:2.7.4.21|MetaCyc:2.7.1.152-RXN|KEGG_REACTION:R09087									molecular_function											owl:Class	
GO:0038104	biolink:NamedThing	nodal receptor complex	A protein complex containing at least a type II activin receptor, a type I activin receptor, and a coreceptor (EGF-CFC protein) such as Cripto or Cryptic. Nodal receptor complexes are capable of binding a nodal protein and transducing the signal into the cell.	tmpzr1t_l9r_go_relaxed.owl	ActRIIB.ALK4.EGF-CFC complex					Nodal signals through activin receptors but (unlike activin) also requires EGF-CFC coreceptors (such as Cripto or Cryptic in mammals) to signal. This term is intended for receptor/co-receptor components and not a nodal-receptor complex.		bf	2012-02-17T11:12:21Z					cellular_component											owl:Class	
GO:0033270	biolink:NamedThing	paranode region of axon	An axon part that is located adjacent to the nodes of Ranvier and surrounded by lateral loop portions of myelin sheath.	tmpzr1t_l9r_go_relaxed.owl	paranode				NIF_Subcellular:sao234066064|NIF_Subcellular:sao936144858									cellular_component											owl:Class	
GO:0045135	biolink:NamedThing	poly(beta-D-mannuronate) lyase activity	Catalysis of the reaction: polysaccharides containing beta-D-mannuronate residues = oligosaccharides with 4-deoxy-alpha-L-erythro-hex-4-enopyranuronosyl end. This reaction is the eliminative cleavage of polysaccharides containing beta-D-mannuronate residues to give oligosaccharides with 4-deoxy-alpha-L-erythro-hex-4-enopyranuronosyl groups at their ends.	tmpzr1t_l9r_go_relaxed.owl	alginate lyase activity|alginase activity|alginase I|poly(beta-D-1,4-mannuronide) lyase activity|alginate lyase I activity|poly(mana) alginate lyase activity				MetaCyc:4.2.2.3-RXN|EC:4.2.2.3									molecular_function											owl:Class	
GO:0110130	biolink:NamedThing	ribitol-5-phosphatase activity	Catalysis of the reaction: ribitol-5-phosphate + H20 = ribitol + phosphate.	tmpzr1t_l9r_go_relaxed.owl					RHEA:47648			kmv	2018-10-08T19:47:57Z					molecular_function											owl:Class	
GO:0000720	biolink:NamedThing	pyrimidine dimer repair by nucleotide-excision repair	The repair of UV-induced T-T, C-T, and C-C dimers by the recognition and removal of the damaged DNA strand from the DNA helix as an oligonucleotide. The small gap left in the DNA helix is filled in by the sequential action of DNA polymerase and DNA ligase.	tmpzr1t_l9r_go_relaxed.owl						Note that the repair of pyrimidine dimers by nucleotide excision repair involves the same gene products that are involved in general nucleotide excision repair. Consider also annotating to other children of the biological process term 'nucleotide-excision repair ; GO:0006289'.								biological_process											owl:Class	
GO:0006290	biolink:NamedThing	pyrimidine dimer repair	The repair of UV-induced T-T, C-T and C-C dimers.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0007211	biolink:NamedThing	octopamine or tyramine signaling pathway	The series of molecular signals generated as a consequence of octopamine or tyramine binding to a cell surface receptor. Octopamine and tyramine are decarboxylation products of tyrosine, and are the invertebrate counterparts of the vertebrate adrenergic transmitters.	tmpzr1t_l9r_go_relaxed.owl	octopamine/tyramine signaling pathway|octopamine or tyramine signalling pathway													biological_process											owl:Class	
GO:0021878	biolink:NamedThing	forebrain astrocyte fate commitment	The process in which the developmental fate of a cell becomes restricted such that it will develop into an astrocyte that resides in the forebrain.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0060018	biolink:NamedThing	astrocyte fate commitment	The commitment of a cells to a specific astrocyte fate and its restriction to develop only into an astrocyte.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1901118	biolink:NamedThing	cephamycin C biosynthetic process	The chemical reactions and pathways resulting in the formation of cephamycin C.	tmpzr1t_l9r_go_relaxed.owl	cephamycin C formation|cephamycin C synthesis|cephamycin C anabolism|cephamycin C biosynthesis							yaf	2012-07-11T03:07:21Z					biological_process											owl:Class	
GO:1904761	biolink:NamedThing	negative regulation of myofibroblast differentiation	Any process that stops, prevents or reduces the frequency, rate or extent of myofibroblast differentiation.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of myofibroblast cell differentiation|downregulation of myofibroblast cell differentiation|inhibition of myofibroblast differentiation|negative regulation of myofibroblast cell differentiation|inhibition of myofibroblast cell differentiation|down regulation of myofibroblast differentiation|down regulation of myofibroblast cell differentiation|downregulation of myofibroblast differentiation|down-regulation of myofibroblast differentiation							rph	2015-10-23T12:15:11Z					biological_process											owl:Class	
GO:0034650	biolink:NamedThing	cortisol metabolic process	The chemical reactions and pathways involving cortisol, the steroid hormone 11-beta-17,21-trihydroxypregn-4-ene-3,20-dione. Cortisol is synthesized from cholesterol in the adrenal gland and controls carbohydrate, fat and protein metabolism and has anti-inflammatory properties.	tmpzr1t_l9r_go_relaxed.owl	cortisol metabolism													biological_process											owl:Class	
GO:0008211	biolink:NamedThing	glucocorticoid metabolic process	The chemical reactions and pathways involving glucocorticoids, hormonal C21 corticosteroids synthesized from cholesterol. Glucocorticoids act primarily on carbohydrate and protein metabolism, and have anti-inflammatory effects.	tmpzr1t_l9r_go_relaxed.owl	glucocorticosteroid metabolic process|glucocorticoid metabolism|glucocorticosteroid metabolism													biological_process											owl:Class	
GO:0099184	biolink:NamedThing	structural constituent of postsynaptic intermediate filament cytoskeleton	The action of a molecule that contributes to the structural integrity of a postsynaptic intermediate filament cytoskeleton.	tmpzr1t_l9r_go_relaxed.owl								dos	2017-12-20T13:45:35Z					molecular_function											owl:Class	
GO:0071391	biolink:NamedThing	cellular response to estrogen stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by an estrogen, C18 steroid hormones that can stimulate the development of female sexual characteristics.	tmpzr1t_l9r_go_relaxed.owl	cellular response to oestrogen stimulus							mah	2009-12-11T04:09:56Z					biological_process											owl:Class	
GO:1904358	biolink:NamedThing	positive regulation of telomere maintenance via telomere lengthening	Any process that activates or increases the frequency, rate or extent of telomere maintenance via telomere lengthening.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of telomere maintenance via telomere lengthening|upregulation of telomere maintenance via telomere lengthening|activation of telomere maintenance via telomere lengthening|up regulation of telomere maintenance via telomere lengthening							nc	2015-06-12T16:53:28Z					biological_process											owl:Class	
GO:0050855	biolink:NamedThing	regulation of B cell receptor signaling pathway	Any process that modulates the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a B cell.	tmpzr1t_l9r_go_relaxed.owl	regulation of B-lymphocyte receptor signaling pathway|regulation of B-cell receptor signaling pathway|regulation of B cell receptor signalling pathway|regulation of B-cell receptor signalling pathway|regulation of B lymphocyte receptor signaling pathway|regulation of B lymphocyte receptor signalling pathway|regulation of B-lymphocyte receptor signalling pathway													biological_process											owl:Class	
GO:0048876	biolink:NamedThing	chemical homeostasis within retina	Any process involved in the maintenance of the internal steady state of the amount of a chemical at the level of the retina.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0097712	biolink:NamedThing	vesicle targeting, trans-Golgi to periciliary membrane compartment	The process in which vesicles formed at the trans-Golgi network are directed to the plasma membrane surrounding the base of the cilium, including the ciliary pocket, mediated by molecules at the vesicle membrane and target membrane surfaces.	tmpzr1t_l9r_go_relaxed.owl								pr	2016-08-05T16:16:28Z					biological_process											owl:Class	
GO:1905058	biolink:NamedThing	calcium-induced calcium release activity involved in regulation of postsynaptic cytosolic calcium ion concentration	Any calcium-induced calcium release activity that is involved in regulation of postsynaptic cytosolic calcium ion concentration.	tmpzr1t_l9r_go_relaxed.owl	calcium-induced calcium release activity involved in regulation of postsynaptic cytosolic calcium levels							dos	2016-03-18T12:31:59Z					molecular_function											owl:Class	
GO:0008531	biolink:NamedThing	riboflavin kinase activity	Catalysis of the reaction: ATP + riboflavin = ADP + FMN + 2 H(+).	tmpzr1t_l9r_go_relaxed.owl	flavokinase activity|riboflavine kinase activity|riboflavin kinase (phosphorylating)|FK|ATP:riboflavin 5'-phosphotransferase activity				Reactome:R-HSA-196964|MetaCyc:RIBOFLAVINKIN-RXN|RHEA:14357|KEGG_REACTION:R00549|EC:2.7.1.26									molecular_function											owl:Class	
GO:0018736	biolink:NamedThing	6-oxo-2-hydroxycyclohexane-1-carboxyl-CoA hydrolase activity	Catalysis of the reaction: 6-oxo-2-hydroxycyclohexane-1-carboxyl-CoA + H2O = 3-hydroxypimeloyl-CoA.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0206									molecular_function											owl:Class	
GO:0004706	biolink:NamedThing	JUN kinase kinase kinase activity	Catalysis of the reaction: JNKK + ATP = JNKK phosphate + ADP. This reaction is the phosphorylation and activation of JUN kinase kinases (JNKKs).	tmpzr1t_l9r_go_relaxed.owl	JNKKK|JNK kinase kinase activity													molecular_function											owl:Class	
GO:0047754	biolink:NamedThing	choline sulfotransferase activity	Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + choline = adenosine 3',5'-diphosphate + choline sulfate + H(+).	tmpzr1t_l9r_go_relaxed.owl	3'-phosphoadenylyl-sulfate:choline sulfotransferase activity|choline sulphotransferase activity|choline sulphokinase activity				EC:2.8.2.6|RHEA:21984|KEGG_REACTION:R01027|MetaCyc:CHOLINE-SULFOTRANSFERASE-RXN									molecular_function											owl:Class	
GO:1903981	biolink:NamedThing	enterobactin binding	Binding to enterobactin.	tmpzr1t_l9r_go_relaxed.owl	enterochelin binding|siderophore binding							mr	2015-03-02T17:21:54Z					molecular_function											owl:Class	
GO:0032979	biolink:NamedThing	protein insertion into mitochondrial inner membrane from matrix	The process in which a protein is incorporated into the mitochondrial inner membrane from the matrix side. This includes membrane insertion of newly synthesized mitochondrially-encoded proteins, and insertion of nuclear-encoded proteins after their import into the mitochondrial matrix.	tmpzr1t_l9r_go_relaxed.owl	protein insertion into mitochondrial inner membrane from matrix side|insertion of proteins into the mitochondrial membrane from the inner side|protein insertion into mitochondrial membrane from inner side													biological_process											owl:Class	
GO:0047177	biolink:NamedThing	glycerophospholipid arachidonoyl-transferase (CoA-independent) activity	Catalysis of the reaction: 1-alkyl-2-lyso-sn-glycero-3-phosphoethanolamine + 1-alkyl-2-arachidonyl-sn-glycero-3-phosphocholine = 1-alkyl-2-lyso-sn-glycero-3-phosphocholine + 1-alkyl-2-arachidonyl-sn-glycero-3-phosphoethanolamine.	tmpzr1t_l9r_go_relaxed.owl	1-organyl-2-arachidonoyl-sn-glycero-3-phosphocholine:1-organyl-2-lyso-sn-glycero-3-phosphoethanolamine arachidonoyltransferase (CoA-independent)|1-organyl-2-arachidonyl-sn-glycero-3-phosphocholine:1-organyl-2-lyso-sn-glycero-3-phosphoethanolamine arachidonoyltransferase (CoA-independent)				MetaCyc:2.3.1.147-RXN|EC:2.3.1.147|RHEA:15409									molecular_function											owl:Class	
GO:0048322	biolink:NamedThing	axial mesodermal cell fate commitment	The process in which a cell becomes committed to become an axial mesoderm cell.	tmpzr1t_l9r_go_relaxed.owl	axial mesoderm cell fate commitment													biological_process											owl:Class	
GO:0018591	biolink:NamedThing	methyl tertiary butyl ether 3-monooxygenase activity	Catalysis of the reaction: methyl tert-butyl ether + 1/2 O2 = tert-butyl alcohol + formaldehyde.	tmpzr1t_l9r_go_relaxed.owl	MTBE 3-monooxygenase activity													molecular_function											owl:Class	
GO:1902799	biolink:NamedThing	regulation of phosphodiesterase I activity	Any process that modulates the frequency, rate or extent of phosphodiesterase I activity.	tmpzr1t_l9r_go_relaxed.owl	regulation of nucleotide pyrophosphatase/phosphodiesterase I activity|regulation of exonuclease I activity|regulation of 5'-nucleotide phosphodiesterase activity|regulation of 5' nucleotide phosphodiesterase/alkaline phosphodiesterase I activity|regulation of 5'NPDE activity|regulation of 5'-NPDase activity|regulation of oligonucleate 5'-nucleotidohydrolase activity|regulation of 5'-PDase activity|regulation of PDE I activity|regulation of 5'-PDE activity|regulation of alkaline phosphodiesterase activity|regulation of phosphodiesterase activity|regulation of 5'-phosphodiesterase activity|regulation of orthophosphoric diester phosphohydrolase activity|regulation of 5'-exonuclease activity							al	2014-03-25T08:55:48Z					biological_process											owl:Class	
GO:0008518	biolink:NamedThing	folate:anion antiporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Folate derivative (out) + anion (in) = folate derivative (in) + anion (out). The Reduced Folate Carrier (RCF(SLC19A1) acts by an antiport mechanism. RCF carries several folate derivatives: MTX, PMX, ratitrexed, pralatrexate, 5-methyl THF, and 5-formyl THF.	tmpzr1t_l9r_go_relaxed.owl	reduced folate carrier activity|reduced folate transporter|reduced folate transmembrane transporter activity	https://github.com/geneontology/go-ontology/issues/15461			TC:2.A.48									molecular_function											owl:Class	
GO:1900272	biolink:NamedThing	negative regulation of long-term synaptic potentiation	Any process that stops, prevents or reduces the frequency, rate or extent of long-term synaptic potentiation.	tmpzr1t_l9r_go_relaxed.owl	down regulation of LTP|down-regulation of long-term synaptic potentiation|negative regulation of long-term potentiation|downregulation of LTP|downregulation of long-term synaptic potentiation|inhibition of long-term synaptic potentiation|down regulation of long-term potentiation|inhibition of long-term potentiation|down regulation of long-term synaptic potentiation|inhibition of LTP|down-regulation of LTP|negative regulation of LTP|down-regulation of long-term potentiation|downregulation of long-term potentiation							rl	2012-04-04T07:17:21Z					biological_process											owl:Class	
GO:1900271	biolink:NamedThing	regulation of long-term synaptic potentiation	Any process that modulates the frequency, rate or extent of long-term synaptic potentiation.	tmpzr1t_l9r_go_relaxed.owl	regulation of LTP|regulation of long-term potentiation							rl	2012-04-04T07:17:13Z					biological_process											owl:Class	
GO:0102194	biolink:NamedThing	protein-fructosamine 3-kinase activity	Catalysis of the reaction: ATP + a [protein]-N6-D-fructosyl-L-lysine <=> ADP + H+ + a [protein]-N6-(3-O-phospho-D-fructosyl)-L-lysine.	tmpzr1t_l9r_go_relaxed.owl	fructosamine-3-kinase activity				EC:2.7.1.171|RHEA:59832|MetaCyc:RXN-12005							GO:0030387		molecular_function											owl:Class	
GO:0018619	biolink:NamedThing	benzene 1,2-dioxygenase activity	Catalysis of the reaction: benzene + H(+) + NADH + O(2) = cis-cyclohexa-3,5-diene-1,2-diol + NAD(+).	tmpzr1t_l9r_go_relaxed.owl	benzene dioxygenase activity|benzene hydroxylase activity|benzene,NADH:oxygen oxidoreductase (1,2-hydroxylating)				UM-BBD_reactionID:r0079|EC:1.14.12.3|KEGG_REACTION:R03543|MetaCyc:BENZENE-12-DIOXYGENASE-RXN|RHEA:13813									molecular_function											owl:Class	
GO:0021946	biolink:NamedThing	deep nuclear neuron cell migration	The directed movement of a deep nuclear neuron from the ventricular zone to the deep hindbrain nuclei.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1904133	biolink:NamedThing	regulation of convergent extension involved in rhombomere morphogenesis	Any process that modulates the frequency, rate or extent of convergent extension involved in rhombomere morphogenesis.	tmpzr1t_l9r_go_relaxed.owl								dph	2015-04-10T21:21:12Z					biological_process											owl:Class	
GO:0008662	biolink:NamedThing	1-phosphofructokinase activity	Catalysis of the reaction: ATP + D-fructose 1-phosphate = ADP + D-fructose 1,6-bisphosphate.	tmpzr1t_l9r_go_relaxed.owl	1-phosphofructokinase (phosphorylating)|ATP:D-fructose-phosphate 6-phosphotransferase activity|fructose-1-phosphate kinase activity|phosphofructokinase 1|D-fructose-1-phosphate kinase activity|fructose 1-phosphate kinase activity				RHEA:14213|EC:2.7.1.56|MetaCyc:1PFRUCTPHOSN-RXN									molecular_function											owl:Class	
GO:0010083	biolink:NamedThing	regulation of vegetative meristem growth	Any process involved in maintaining the size and shape of a vegetative meristem.	tmpzr1t_l9r_go_relaxed.owl	regulation of vegetative meristem size													biological_process											owl:Class	
GO:2000440	biolink:NamedThing	regulation of toll-like receptor 15 signaling pathway	Any process that modulates the frequency, rate or extent of toll-like receptor 15 signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	regulation of TLR15 signaling pathway|regulation of toll-like receptor 15 signalling pathway							bf	2011-03-04T10:28:24Z					biological_process											owl:Class	
GO:0008365	biolink:NamedThing	adult chitin-based cuticle development	Synthesis and deposition of the chitin-based cuticle of adults following the apolysis of the pupal cuticle. The adult insect cuticle contains cuticullin, a protein epicuticle and a lamellate procuticle. An example of this process is adult chitin-based cuticle development in Drosophila melanogaster.	tmpzr1t_l9r_go_relaxed.owl	adult chitin-based cuticle anabolism|adult cuticle synthesis|adult chitin-based cuticle synthesis|adult chitin-based cuticle biosynthetic process|adult cuticle anabolism|adult chitin-based cuticle formation|adult cuticle biosynthetic process|adult cuticle formation													biological_process											owl:Class	
GO:0106227	biolink:NamedThing	peptidyl-lysine glutarylation	The glutarylation of a lysine residue in a protein.	tmpzr1t_l9r_go_relaxed.owl								hjd	2019-10-17T18:57:19Z					biological_process											owl:Class	
GO:0120323	biolink:NamedThing	lipid ubiquitination	The process in which one or more ubiquitin groups are added to a lipid.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/21857						krc	2021-07-20T18:58:34Z					biological_process											owl:Class	
GO:0120322	biolink:NamedThing	lipid modification by small protein conjugation	A lipid modification process in which one or more groups of a small protein, such as ubiquitin or a ubiquitin-like protein, are covalently attached to a target lipid.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/21857						krc	2021-07-20T18:53:03Z					biological_process											owl:Class	
GO:2000100	biolink:NamedThing	regulation of establishment or maintenance of bipolar cell polarity regulating cell shape	Any process that modulates the frequency, rate or extent of establishment or maintenance of bipolar cell polarity regulating cell shape.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-09-14T04:44:57Z					biological_process											owl:Class	
GO:0051797	biolink:NamedThing	regulation of hair follicle development	Any process that modulates the frequency, rate or extent of hair follicle development.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0032428	biolink:NamedThing	beta-N-acetylgalactosaminidase activity	Catalysis of the hydrolysis of terminal non-reducing N-acetyl-D-galactosamine residues in N-acetyl-beta-D-galactosaminides.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:3.2.1.53-RXN|EC:3.2.1.53									molecular_function											owl:Class	
GO:0004563	biolink:NamedThing	beta-N-acetylhexosaminidase activity	Catalysis of the hydrolysis of terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides.	tmpzr1t_l9r_go_relaxed.owl	N-acetyl-beta-glucosaminidase activity|beta-N-acetyl-D-hexosaminide N-acetylhexosaminohydrolase activity|beta-D-hexosaminidase activity|hexosaminidase A|beta-acetylaminodeoxyhexosidase activity|N-acetyl-beta-D-hexosaminidase activity|beta-acetylhexosaminidinase activity|beta-N-acetyl-D-hexosaminidase activity|beta-D-N-acetylhexosaminidase activity|beta-hexosaminidase activity|N-acetyl-beta-hexosaminidase activity|N-acetylhexosaminidase activity				Reactome:R-HSA-3656259|Reactome:R-HSA-9638075|EC:3.2.1.52|Reactome:R-HSA-3662344|Reactome:R-HSA-9035978|Reactome:R-HSA-9035982|Reactome:R-HSA-2162225|Reactome:R-HSA-9035983|Reactome:R-HSA-1605632|MetaCyc:3.2.1.52-RXN|Reactome:R-HSA-1605595|Reactome:R-HSA-9638078|Reactome:R-HSA-9035976|Reactome:R-HSA-2105001|Reactome:R-HSA-1638053|Reactome:R-HSA-9638076									molecular_function											owl:Class	
GO:0120055	biolink:NamedThing	small intestinal transit	Migration of ingested material along the length of the small intestine.	tmpzr1t_l9r_go_relaxed.owl	small intestine transit|small bowel transit							krc	2017-06-13T20:46:41Z					biological_process											owl:Class	
GO:0031159	biolink:NamedThing	positive regulation of aggregate size involved in sorocarp development	Any process that increases the size of the aggregate formed during sorocarp formation.	tmpzr1t_l9r_go_relaxed.owl	upregulation of aggregate size|up regulation of aggregate size|activation of aggregate size|up-regulation of aggregate size|stimulation of aggregate size													biological_process											owl:Class	
GO:0036311	biolink:NamedThing	chitin disaccharide deacetylase activity	Catalysis of the reaction: 2-(acetylamino)-4-O-[2-(acetylamino)-2-deoxy-beta-D-glucopyranosyl]-2-deoxy-beta-D-glucopyranose + H2O = 2-(acetylamino)-4-O-(2-amino-2-deoxy-beta-D-glucopyranosyl)-2-deoxy-beta-D-glucopyranose + acetate.	tmpzr1t_l9r_go_relaxed.owl	chitin oligosaccharide amidohydrolase activity|chitobiose amidohydrolase activity|chitin oligosaccharide deacetylase activity					In contrast to EC:3.5.1.41 (chitin deacetylase) this enzyme is specific for the chitin disaccharide.		bf	2012-08-15T15:18:09Z					molecular_function											owl:Class	
GO:0030878	biolink:NamedThing	thyroid gland development	The process whose specific outcome is the progression of the thyroid gland over time, from its formation to the mature structure. The thyroid gland is an endoderm-derived gland that produces thyroid hormone.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:2000939	biolink:NamedThing	regulation of plant-type cell wall cellulose catabolic process	Any process that modulates the frequency, rate or extent of plant-type cell wall cellulose catabolic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of plant-type cell wall polysaccharide breakdown							tt	2011-08-01T02:07:11Z					biological_process											owl:Class	
GO:1990346	biolink:NamedThing	BID-BCL-xl complex	A heterodimeric protein complex consisting of BID and BCL-xl, members of the Bcl-2 family of anti- and proapoptotic regulators.	tmpzr1t_l9r_go_relaxed.owl								bhm	2014-03-25T00:18:41Z					cellular_component											owl:Class	
GO:0102262	biolink:NamedThing	tRNA-dihydrouridine16 synthase activity	Catalysis of the reaction: a 5,6-dihydrouracil16 in tRNA + NAD(P) <=> H+ + a uracil16 in tRNA + NAD(P)H.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-12454									molecular_function											owl:Class	
GO:0030597	biolink:NamedThing	RNA glycosylase activity	Catalysis of the hydrolysis of N-glycosidic bonds in an RNA molecule.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0051538	biolink:NamedThing	3 iron, 4 sulfur cluster binding	Binding to a 3 iron, 4 sulfur (3Fe-4S) cluster; this cluster consists of three iron atoms, with the inorganic sulfur atoms found between the irons and acting as bridging ligands. It is essentially a 4Fe-4S cluster with one iron missing.	tmpzr1t_l9r_go_relaxed.owl	3Fe-4S cluster binding|iron-sulphur cluster 3Fe-4S binding|triiron tetrasulphide cluster binding|3 Fe 4 S cluster binding|3 iron, 4 sulphur cluster binding|iron-sulfur cluster 3Fe-4S binding|triiron tetrasulfide cluster binding													molecular_function											owl:Class	
GO:0009670	biolink:NamedThing	triose-phosphate:phosphate antiporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: triose-phosphate(out) + phosphate(in) = triose-phosphate(in) + phosphate(out).	tmpzr1t_l9r_go_relaxed.owl	triose phosphate translocator|triose phosphate antiporter|dihydroxyacetone phosphate:phosphate antiporter activity|TPT											GO:0015122		molecular_function											owl:Class	
GO:0015693	biolink:NamedThing	magnesium ion transport	The directed movement of magnesium (Mg) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	magnesium transport													biological_process											owl:Class	
GO:0034315	biolink:NamedThing	regulation of Arp2/3 complex-mediated actin nucleation	Any process that modulates the frequency, rate or extent of actin nucleation mediated by the Arp2/3 complex and interacting proteins.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0043073	biolink:NamedThing	germ cell nucleus	The nucleus of a germ cell, a reproductive cell in multicellular organisms.	tmpzr1t_l9r_go_relaxed.owl	germ-cell nucleus													cellular_component											owl:Class	
GO:0140471	biolink:NamedThing	positive regulation of transepithelial migration of symbiont in host	Any process that activates or increases the frequency, rate or extent of transepithelial migration of symbiont in host.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of transmigration of symbiont in host	https://github.com/geneontology/go-ontology/issues/19601						pg	2020-06-11T15:32:38Z					biological_process											owl:Class	
GO:0061576	biolink:NamedThing	acyl-CoA ceramide synthase complex	A protein complex that catalyzes the reaction acyl-CoA + sphingosine = CoA + N-acylsphingosine. In S. cerevisiae it contains three subunits: lag1, lac1 and lip1.	tmpzr1t_l9r_go_relaxed.owl								dph	2013-10-24T14:42:06Z					cellular_component											owl:Class	
GO:0006157	biolink:NamedThing	deoxyadenosine catabolic process	The chemical reactions and pathways resulting in the breakdown of deoxyadenosine, 2-deoxyribosyladenine, one of the four major nucleosides of DNA.	tmpzr1t_l9r_go_relaxed.owl	deoxyadenosine phosphorolysis|deoxyadenosine catabolism|deoxyadenosine degradation|deoxyadenosine breakdown											GO:0006159		biological_process											owl:Class	
GO:0048824	biolink:NamedThing	pigment cell precursor differentiation	The process in which a relatively unspecialized cell acquires specialized features of a pigment cell precursor.	tmpzr1t_l9r_go_relaxed.owl	chromatophore precursor differentiation													biological_process											owl:Class	
GO:0030135	biolink:NamedThing	coated vesicle	Small membrane-bounded organelle formed by pinching off of a coated region of membrane. Some coats are made of clathrin, whereas others are made from other proteins.	tmpzr1t_l9r_go_relaxed.owl					NIF_Subcellular:sao1985096626							GO:0005909		cellular_component											owl:Class	
GO:0039701	biolink:NamedThing	microtubule-dependent intracellular transport of viral material towards cell periphery	The directed movement of the viral genome or a viral particle towards the cell periphery using host microtubules. Mostly used by viruses that replicate their genome near or in the nucleus to allows newly assembled viral progeny to reach the plasma membrane.	tmpzr1t_l9r_go_relaxed.owl					VZ:1816			bf	2013-11-06T16:09:57Z					biological_process											owl:Class	
GO:0075519	biolink:NamedThing	microtubule-dependent intracellular transport of viral material	The directed movement of the viral genome or viral particle within the host cell cytoplasm along host microtubules. Microtubule-dependent transport involves motor proteins like dynein and kinesin and is mostly used by viruses that target their genomes to the nucleus.	tmpzr1t_l9r_go_relaxed.owl								jl	2011-08-03T01:45:25Z					biological_process											owl:Class	
GO:0047044	biolink:NamedThing	androstan-3-alpha,17-beta-diol dehydrogenase activity	Catalysis of the reaction: NAD+ + androstan-3-alpha,17-beta-diol = 17-beta-hydroxyandrostan-3-one + NADH + H+.	tmpzr1t_l9r_go_relaxed.owl	20beta-hydroxysteroid dehydrogenase activity|20beta-HSD|(R)-20-hydroxysteroid dehydrogenase activity|dehydrogenase, 20beta-hydroxy steroid|3alpha,20beta-hydroxysteroid:NAD+-oxidoreductase activity|NADH-20beta-hydroxysteroid dehydrogenase activity|delta4-3-ketosteroid hydrogenase activity|3alpha(or 20beta)-hydroxysteroid dehydrogenase activity|3-alpha(or 20-beta)-hydroxysteroid dehydrogenase activity|cortisone reductase activity|3alpha(or 20beta)-hydroxysteroid:NAD+ oxidoreductase activity				EC:1.1.1.53|RHEA:22400|MetaCyc:1.1.1.53-RXN									molecular_function											owl:Class	
GO:0110061	biolink:NamedThing	regulation of angiotensin-activated signaling pathway	Any process that modulates the frequency, rate or extent of the angiotensin-activated signaling pathway.	tmpzr1t_l9r_go_relaxed.owl								kmv	2017-10-26T17:37:37Z					biological_process											owl:Class	
GO:1904310	biolink:NamedThing	cellular response to cordycepin	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cordycepin stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to 3'-deoxyadenosine							sl	2015-06-10T17:10:35Z					biological_process											owl:Class	
GO:0015854	biolink:NamedThing	guanine transport	The directed movement of guanine, 2-amino-6-hydroxypurine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0032031	biolink:NamedThing	myosin I head/neck binding	Binding to the head/neck region of a myosin I heavy chain.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0106407	biolink:NamedThing	Glc2Man9GlcNAc2 oligosaccharide glucosidase activity	Catalysis of the reaction: Glc(2)Man(9)GlcNAc(2)-[protein] + H(2)O = GlcMan(9)GlcNAc(2)-[protein] + beta-D-glucopyranose.	tmpzr1t_l9r_go_relaxed.owl	Glucosidase II					Trims Glc alpha 1,3 Glc bond in Glc2Man9GlcNAc2 oligosaccharide in inmature glycoproteins.		hjd	2021-10-28 00:35:46+00:00					molecular_function											owl:Class	
GO:0004573	biolink:NamedThing	Glc3Man9GlcNAc2 oligosaccharide glucosidase activity	Catalysis of the exohydrolysis of the non-reducing terminal glucose residue in the mannosyl-oligosaccharide Glc(3)Man(9)GlcNAc(2).	tmpzr1t_l9r_go_relaxed.owl	trimming glucosidase I|mannosyl-oligosaccharide glucosidase (processing A-glucosidase I) activity|mannosyl-oligosaccharide glucosidase activity|mannosyl-oligosaccharide glucohydrolase activity|processing A-glucosidase I activity				RHEA:55988|MetaCyc:3.2.1.106-RXN|Reactome:R-HSA-4793947|Reactome:R-HSA-532678|EC:3.2.1.106|Reactome:R-HSA-9694364									molecular_function											owl:Class	
GO:0050046	biolink:NamedThing	delta7-sterol 5(6)-desaturase activity	Catalysis of the reaction: a delta(7)-sterol + 2 ferrocytochrome b5 + O2 + 2 H+ -> a delta(5,7)-sterol + 2 ferricytochrome b5 + 2 H2O.	tmpzr1t_l9r_go_relaxed.owl	lathosterol oxidase activity|delta7-sterol 5-desaturase activity|delta7-sterol-C5(6)-desaturase activity|lathosterol 5-desaturase activity|5-DES|delta7-sterol delta5-dehydrogenase activity	https://github.com/geneontology/go-ontology/issues/21133			EC:1.14.19.20|MetaCyc:1.14.21.6-RXN|RHEA:46556									molecular_function											owl:Class	
GO:0070704	biolink:NamedThing	sterol desaturase activity	Catalysis of the introduction of a double bond into a sterol molecule.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-06-08T03:53:44Z					molecular_function											owl:Class	
GO:0102610	biolink:NamedThing	(+)-secoisolariciresinol glucosyltransferase activity	Catalysis of the reaction: (+)-secoisolariciresinol + UDP-alpha-D-glucose <=> (+)-secoisolariciresinol monoglucoside + UDP + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-15442									molecular_function											owl:Class	
GO:0002856	biolink:NamedThing	negative regulation of natural killer cell mediated immune response to tumor cell	Any process that stops, prevents, or reduces the frequency, rate, or extent of natural killer cell mediated immune response to a tumor cell.	tmpzr1t_l9r_go_relaxed.owl	inhibition of natural killer cell mediated immune response to tumor cell|down-regulation of natural killer cell mediated immune response to tumor cell|downregulation of natural killer cell mediated immune response to tumor cell|down regulation of natural killer cell mediated immune response to tumor cell													biological_process											owl:Class	
GO:0018045	biolink:NamedThing	C-terminal peptidyl-lysine amidation	The formation of a C-terminal peptidyl-lysine amide by hydrolysis and oxidation of an interior Lys-Gly peptide in a secreted protein.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0092									biological_process											owl:Class	
GO:2000561	biolink:NamedThing	regulation of CD4-positive, alpha-beta T cell proliferation	Any process that modulates the frequency, rate or extent of CD4-positive, alpha-beta T cell proliferation.	tmpzr1t_l9r_go_relaxed.owl								ebc	2011-04-03T09:01:04Z					biological_process											owl:Class	
GO:1903418	biolink:NamedThing	protein localization to plasma membrane of cell tip	A process in which a protein is transported to, or maintained in, a location within a plasma membrane of cell tip.	tmpzr1t_l9r_go_relaxed.owl	protein localisation to plasma membrane of cell tip|protein localisation in plasma membrane of cell tip|protein localization in plasma membrane of cell tip							mah	2014-09-08T15:08:51Z					biological_process											owl:Class	
GO:0000034	biolink:NamedThing	adenine deaminase activity	Catalysis of the reaction: adenine + H2O = hypoxanthine + NH3.	tmpzr1t_l9r_go_relaxed.owl	adenase activity|adenine aminase activity|adenine aminohydrolase activity|ADase activity				MetaCyc:ADENINE-DEAMINASE-RXN|EC:3.5.4.2|RHEA:23688									molecular_function											owl:Class	
GO:0004152	biolink:NamedThing	dihydroorotate dehydrogenase activity	Catalysis of the reaction: (S)-dihydroorotate + A = AH(2) + orotate.	tmpzr1t_l9r_go_relaxed.owl	dihydoorotic acid dehydrogenase activity|(S)-dihydroorotate:quinone oxidoreductase activity|(DHO) dehydrogenase activity|dihydroorotate:ubiquinone oxidoreductase activity|DHOdehase activity				EC:1.3.5.2|RHEA:18073|Reactome:R-HSA-73569|MetaCyc:DIHYDROOROTATE-DEHYDROGENASE-RXN|KEGG_REACTION:R01868									molecular_function											owl:Class	
GO:0010364	biolink:NamedThing	regulation of ethylene biosynthetic process	Any process that modulates the frequency, rate, or extent of an ethylene biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0035238	biolink:NamedThing	vitamin A biosynthetic process	The chemical reactions and pathways resulting in the formation of any of the vitamin A compounds, retinol, retinal (retinaldehyde) and retinoic acid. Animals cannot synthesize vitamin A de novo, but form it through oxidative cleavage of carotenoids.	tmpzr1t_l9r_go_relaxed.owl	vitamin A biosynthesis|vitamin A synthesis|vitamin A formation|vitamin A anabolism													biological_process											owl:Class	
GO:0140330	biolink:NamedThing	xenobiotic detoxification by transmembrane export across the cell outer membrane	A process that reduces or removes the toxicity of a xenobiotic by exporting it outside the cell through the outer membrane.	tmpzr1t_l9r_go_relaxed.owl								pg	2019-05-03T10:35:57Z					biological_process											owl:Class	
GO:0120319	biolink:NamedThing	long-chain fatty acid omega-1 hydroxylase activity	Catalysis of the reaction: an (omega-1)-ethyl long-chain fatty acid + O2 + reduced [NADPH-hemoprotein reductase] = an (omega-1)-hydroxy-long-chain fatty acid + H+ + H2O + oxidized [NADPH-hemoprotein reductase.	tmpzr1t_l9r_go_relaxed.owl	cytochrome P450 fatty acid omega-1 hydroxylase activity	https://github.com/geneontology/go-ontology/issues/21648			RHEA:60936			krc	2021-06-21T18:31:38Z					molecular_function											owl:Class	
GO:0102097	biolink:NamedThing	(22S)-22-hydroxy-5alpha-campestan-3-one C-23 hydroxylase activity	Catalysis of the reaction: (5alpha,22S,24R)-22-hydroxyergostan-3-one + O2 + NADPH + H+ <=> 3-dehydro-6-deoxoteasterone + NADP + H2O.	tmpzr1t_l9r_go_relaxed.owl					RHEA:27325|MetaCyc:RXN-11101|EC:1.14.14.147									molecular_function											owl:Class	
GO:1904793	biolink:NamedThing	regulation of euchromatin binding	Any process that modulates the frequency, rate or extent of euchromatin binding.	tmpzr1t_l9r_go_relaxed.owl								nc	2015-11-09T11:43:04Z					biological_process											owl:Class	
GO:0070206	biolink:NamedThing	protein trimerization	The formation of a protein trimer, a macromolecular structure consisting of three noncovalently associated identical or nonidentical subunits.	tmpzr1t_l9r_go_relaxed.owl	protein trimer assembly|protein trimer biosynthesis|protein trimer formation|protein trimer biosynthetic process													biological_process											owl:Class	
GO:1990859	biolink:NamedThing	cellular response to endothelin	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an endothelin stimulus. Endothelin is any of three secretory vasoconstrictive peptides (endothelin-1, -2, -3).	tmpzr1t_l9r_go_relaxed.owl								sl	2015-09-24T15:39:48Z					biological_process											owl:Class	
GO:1902156	biolink:NamedThing	positive regulation of response to G1 DNA damage checkpoint signaling	Any process that activates or increases the frequency, rate or extent of response to G1 DNA damage checkpoint signaling.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of response to mitotic cell cycle G1/S transition DNA damage checkpoint signaling|upregulation of response to signal involved in mitotic cell cycle G1/S transition DNA damage checkpoint|up regulation of response to signal involved in mitotic cell cycle G1/S transition DNA damage checkpoint|positive regulation of response to signal involved in mitotic cell cycle G1/S transition DNA damage checkpoint|up regulation of response to G1 DNA damage checkpoint signaling|up-regulation of response to mitotic cell cycle G1/S transition DNA damage checkpoint signaling|up-regulation of response to signal involved in mitotic cell cycle G1/S transition DNA damage checkpoint|upregulation of response to G1 DNA damage checkpoint signaling|activation of response to mitotic cell cycle G1/S transition DNA damage checkpoint signaling|up-regulation of response to G1 DNA damage checkpoint signaling|activation of mitotic cell cycle G1/S transition DNA damage checkpoint effector process|up regulation of response to mitotic cell cycle G1/S transition DNA damage checkpoint signaling|activation of response to G1 DNA damage checkpoint signaling|upregulation of response to mitotic cell cycle G1/S transition DNA damage checkpoint signaling|positive regulation of mitotic cell cycle G1/S transition DNA damage checkpoint effector process|upregulation of mitotic cell cycle G1/S transition DNA damage checkpoint effector process|up-regulation of mitotic cell cycle G1/S transition DNA damage checkpoint effector process|activation of response to signal involved in mitotic cell cycle G1/S transition DNA damage checkpoint|up regulation of mitotic cell cycle G1/S transition DNA damage checkpoint effector process							jl	2013-05-21T15:44:58Z					biological_process											owl:Class	
GO:0031485	biolink:NamedThing	myosin XV complex	A myosin complex containing a class XV myosin heavy chain and associated light chains. Myosin XV is single headed, and has a large extension (1200aa) at the N-terminus of the motor domain, two IQ motifs and a tail with a similar domain structure to that of the tail of myosin VII.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0035455	biolink:NamedThing	response to interferon-alpha	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-alpha stimulus. Interferon-alpha is a type I interferon.	tmpzr1t_l9r_go_relaxed.owl	response to lymphoblastoid interferon|response to leukocyte interferon|response to lymphoblast interferon|response to interferon alfa-n1|response to interferon alfa-n3							bf	2010-04-16T10:57:16Z					biological_process											owl:Class	
GO:0034306	biolink:NamedThing	regulation of sexual sporulation	Any process that modulates the frequency, rate or extent of spore formation from the products of meiosis. An example of this is found in Saccharomyces cerevisiae.	tmpzr1t_l9r_go_relaxed.owl	regulation of sexual spore formation|MAPKKK cascade during sporulation|regulation of meiotic sporulation|regulation of meiotic spore formation													biological_process											owl:Class	
GO:0006932	biolink:NamedThing	substrate-dependent cell migration, cell contraction	The translocation of the cell body forward during cell migration, mediated by tractional force on its substrate and tension in the cortical cytoskeleton. Adhesions transmit propulsive forces and serve as traction points over which the cell moves.	tmpzr1t_l9r_go_relaxed.owl	substrate-bound cell migration, cell contraction													biological_process											owl:Class	
GO:0120098	biolink:NamedThing	procentriole	A cellular structure that is the site of a developing centriole, which will become a microtubule organizing center. During the canonical pathway of centriole duplication that occurs during the cell division cycle, procentrioles grow at the proximal ends of both mother and daughter centrioles. In the newly divided cells, the original mother and daughter centrioles become mother centrioles while the procentrioles become the new daughter centrioles. Procentrioles can also arise from de novo pathways that occur in multiciliated cells. In ciliated epithelial cells, numerous procentrioles arise form electron dense material referred to as fibrous granules and deuterosomes. The pathway of procentriole formation in multiciliated protists appears to be similar to that in mammalian multiciliated epithelium. In sperm of primative land plants, multiple procentrioles are formed from a blepharoplast giving rise to multicilated sperm cells.	tmpzr1t_l9r_go_relaxed.owl								krc	2017-09-28T21:22:56Z					cellular_component											owl:Class	
GO:1900033	biolink:NamedThing	negative regulation of trichome patterning	Any process that stops, prevents or reduces the frequency, rate or extent of trichome patterning.	tmpzr1t_l9r_go_relaxed.owl	inhibition of trichome pattern formation|negative regulation of trichome spacing|down regulation of trichome pattern biosynthesis|downregulation of trichome patterning|downregulation of trichome pattern formation|down-regulation of trichome pattern specification|negative regulation of trichome pattern formation|down-regulation of trichome pattern formation|inhibition of trichome distribution|down regulation of trichome patterning|down-regulation of trichome spacing|down regulation of trichome distribution|downregulation of trichome pattern biosynthesis|down-regulation of trichome patterning|inhibition of trichome pattern specification|down-regulation of trichome pattern biosynthesis|downregulation of trichome distribution|negative regulation of trichome pattern biosynthesis|down regulation of trichome pattern specification|down-regulation of trichome distribution|negative regulation of trichome pattern specification|down regulation of trichome spacing|negative regulation of trichome distribution|inhibition of trichome patterning|downregulation of trichome spacing|inhibition of trichome pattern biosynthesis|inhibition of trichome spacing|downregulation of trichome pattern specification|down regulation of trichome pattern formation							tb	2012-01-13T11:10:50Z					biological_process											owl:Class	
GO:0047907	biolink:NamedThing	furylfuramide isomerase activity	Catalysis of the reaction: (E)-2-(2-furyl)-3-(5-nitro-2-furyl)acrylamide = (Z)-2-(2-furyl)-3-(5-nitro-2-furyl)acrylamide.	tmpzr1t_l9r_go_relaxed.owl	2-(2-furyl)-3-(5-nitro-2-furyl)acrylamide cis-trans-isomerase activity				RHEA:21848|MetaCyc:FURYLFURAMIDE-ISOMERASE-RXN|KEGG_REACTION:R04538|EC:5.2.1.6									molecular_function											owl:Class	
GO:0047819	biolink:NamedThing	D-glutamate(D-aspartate) oxidase activity	Catalysis of the reaction: D-glutamate + H2O + O2 = 2-oxoglutarate + NH3 + H2O2, and D-aspartate + H2O + O2 = oxaloacetate + NH3 + H2O2.	tmpzr1t_l9r_go_relaxed.owl	D-glutamic-aspartic oxidase activity|D-monoaminodicarboxylic acid oxidase activity|D-glutamate(D-aspartate):oxygen oxidoreductase (deaminating)				MetaCyc:D-GLUTAMATED-ASPARTATE-OXIDASE-RXN|EC:1.4.3.15	For the individual reactions, see instead 'D-glutamate oxidase activity ;GO:0047821' and 'D-aspartate oxidase activity ; GO:0008445'.								molecular_function											owl:Class	
GO:0035631	biolink:NamedThing	CD40 receptor complex	A protein complex that contains at least CD40 (a cell surface receptor of the tumour necrosis factor receptor (TNFR) superfamily), and other signaling molecules.	tmpzr1t_l9r_go_relaxed.owl								bf	2010-12-21T10:35:05Z					cellular_component											owl:Class	
GO:1903331	biolink:NamedThing	positive regulation of iron-sulfur cluster assembly	Any process that activates or increases the frequency, rate or extent of iron-sulfur cluster assembly.	tmpzr1t_l9r_go_relaxed.owl	activation of iron-sulfur cluster biosynthesis|up regulation of iron-sulfur cluster assembly|upregulation of iron-sulphur cluster assembly|activation of iron-sulfur cluster assembly|up-regulation of iron-sulfur cluster biosynthesis|upregulation of iron-sulfur cluster biosynthesis|positive regulation of iron-sulphur cluster assembly|positive regulation of iron-sulfur cluster biosynthesis|activation of iron-sulphur cluster assembly|up-regulation of iron-sulfur cluster assembly|up-regulation of iron-sulphur cluster assembly|up regulation of iron-sulfur cluster biosynthesis|up regulation of iron-sulphur cluster assembly|upregulation of iron-sulfur cluster assembly							vw	2014-08-18T13:12:57Z					biological_process											owl:Class	
GO:0070781	biolink:NamedThing	response to biotin	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biotin stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to coenzyme R|response to vitamin B7|response to Bios IIB|response to vitamin H							mah	2009-07-02T02:34:43Z					biological_process											owl:Class	
GO:0043938	biolink:NamedThing	positive regulation of sporulation	Any process that activates, maintains or increases the frequency, rate or extent of sporulation, the process whose specific outcome is the progression of a spore over time, from its initiation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0003684	biolink:NamedThing	damaged DNA binding	Binding to damaged DNA.	tmpzr1t_l9r_go_relaxed.owl	DNA repair enzyme|DNA repair protein													molecular_function											owl:Class	
GO:0045514	biolink:NamedThing	interleukin-16 receptor binding	Binding to an interleukin-16 receptor.	tmpzr1t_l9r_go_relaxed.owl	interleukin-16 receptor ligand|IL-16													molecular_function											owl:Class	
GO:1901849	biolink:NamedThing	nicotinate biosynthetic process	The chemical reactions and pathways resulting in the formation of nicotinate.	tmpzr1t_l9r_go_relaxed.owl	nicotinate formation|nicotinate anabolism|nicotinate biosynthesis|nicotinate synthesis							yaf	2013-01-28T11:23:57Z					biological_process											owl:Class	
GO:0061107	biolink:NamedThing	seminal vesicle development	The progression of the seminal vesicle over time, from its formation to the mature structure. The seminal vesicle is a gland that contributes to the production of semen.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-04-30T10:17:30Z					biological_process											owl:Class	
GO:0098547	biolink:NamedThing	lumenal side of Golgi membrane	The side of the Golgi membrane that faces the lumen.	tmpzr1t_l9r_go_relaxed.owl								dos	2013-12-03T10:44:23Z					cellular_component											owl:Class	
GO:0006542	biolink:NamedThing	glutamine biosynthetic process	The chemical reactions and pathways resulting in the formation of glutamine, 2-amino-4-carbamoylbutanoic acid.	tmpzr1t_l9r_go_relaxed.owl	glutamine anabolism|glutamine synthesis|glutamine biosynthesis|glutamine formation				MetaCyc:GLNSYN-PWY									biological_process											owl:Class	
GO:0016075	biolink:NamedThing	rRNA catabolic process	The chemical reactions and pathways resulting in the breakdown of rRNA, ribosomal RNA, a structural constituent of ribosomes.	tmpzr1t_l9r_go_relaxed.owl	rRNA catabolism|rRNA degradation|rRNA breakdown													biological_process											owl:Class	
GO:0061627	biolink:NamedThing	S-methylmethionine-homocysteine S-methyltransferase activity	Catalysis of the reaction: S-methyl-L-methionine + L-homocysteine = 2 L-methionine + H+.	tmpzr1t_l9r_go_relaxed.owl	S-methylmethionine homocysteine transmethylase activity|homocysteine methyltransferase activity|methylmethionine:homocysteine methyltransferase activity|homocysteine transmethylase activity				RHEA:26337|Reactome:R-HSA-5696838			dph	2014-05-14T14:32:02Z					molecular_function											owl:Class	
GO:0042299	biolink:NamedThing	lupeol synthase activity	Catalysis of the reaction: (S)-2,3-epoxysqualene = lupeol. This reaction is the cyclization of (S)-2,3-epoxysqualene (2,3-oxidosqualene) to lupeol.	tmpzr1t_l9r_go_relaxed.owl	oxidosqualene:lupeol cyclase activity				MetaCyc:RXN-111|EC:5.4.99.41|RHEA:31383									molecular_function											owl:Class	
GO:0070798	biolink:NamedThing	positive regulation of cleistothecium development	Any process that activates or increases the frequency, rate or extent of cleistothecium development, a process that leads to the formation of a cleistothecium. The cleistothecium is a closed sexual fruiting body that contains ascospores in linear asci, characteristic of some filamentous Ascomycete fungi such as members of the genera Aspergillus and Emericella.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-07-08T03:36:43Z					biological_process											owl:Class	
GO:2000975	biolink:NamedThing	positive regulation of pro-B cell differentiation	Any process that activates or increases the frequency, rate or extent of pro-B cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of pro-B lymphocyte differentiation|positive regulation of pro-B cell development							yaf	2011-08-02T03:05:53Z					biological_process											owl:Class	
GO:1905801	biolink:NamedThing	positive regulation of intraciliary retrograde transport	Any process that activates or increases the frequency, rate or extent of intraciliary retrograde transport.	tmpzr1t_l9r_go_relaxed.owl	activation of intraflagellar retrograde transport|positive regulation of intraflagellar retrograde transport|up-regulation of intraflagellar retrograde transport|up-regulation of intraciliary retrograde transport|upregulation of intraflagellar retrograde transport|activation of intraciliary retrograde transport|up regulation of intraciliary retrograde transport|upregulation of intraciliary retrograde transport|up regulation of intraflagellar retrograde transport							hbye	2017-01-11T12:58:35Z					biological_process											owl:Class	
GO:0047382	biolink:NamedThing	methylphosphothioglycerate phosphatase activity	Catalysis of the reaction: S-methyl-3-phospho-1-thio-D-glycerate + H(2)O = S-methyl-1-thio-D-glycerate + phosphate.	tmpzr1t_l9r_go_relaxed.owl	S-methyl-3-phospho-1-thio-D-glycerate phosphohydrolase activity|methylthiophosphoglycerate phosphatase activity				RHEA:16081|EC:3.1.3.14|MetaCyc:3.1.3.14-RXN|KEGG_REACTION:R04317									molecular_function											owl:Class	
GO:0048108	biolink:NamedThing	peptide cross-linking via 4-amino-3-isothiazolidinone	The formation of 4-amino-3-isothiazolinone cross-links by the formation of a sulfenylamide bond between cysteine or cysteine sulfenic acid, and the alpha-amido of the following residue.	tmpzr1t_l9r_go_relaxed.owl						Note that this is a generic parent because the identity of the second amino acid is not critical for formation of the cross-link.								biological_process											owl:Class	
GO:0071665	biolink:NamedThing	gamma-catenin-TCF7L2 complex	A protein complex that contains gamma-catenin and TCF7L2 (TCF4), binds to the TCF DNA motif within a promoter element, and is involved in the regulation of WNT target gene transcription.	tmpzr1t_l9r_go_relaxed.owl	plakoglobin-TCF4 complex|gamma-catenin-TCF4 complex							mah	2010-02-12T03:23:08Z					cellular_component											owl:Class	
GO:0071664	biolink:NamedThing	catenin-TCF7L2 complex	A protein complex that contains a catenin and TCF7L2 (TCF4), binds to the TCF DNA motif within a promoter element, and is involved in the regulation of WNT target gene transcription.	tmpzr1t_l9r_go_relaxed.owl	catenin-TCF4 complex							mah	2010-02-12T03:19:16Z					cellular_component											owl:Class	
GO:0042700	biolink:NamedThing	luteinizing hormone signaling pathway	The series of molecular signals mediated by luteinizing hormone.	tmpzr1t_l9r_go_relaxed.owl	luteinizing hormone signalling pathway													biological_process											owl:Class	
GO:0033892	biolink:NamedThing	deoxyribonuclease (pyrimidine dimer) activity	Catalysis of the endonucleolytic cleavage near pyrimidine dimers to products with 5'-phosphate.	tmpzr1t_l9r_go_relaxed.owl	endodeoxyribonuclease (pyrimidine dimer) activity|T4 endonuclease V activity|bacteriophage T4 endodeoxyribonuclease V activity				MetaCyc:3.1.25.1-RXN|EC:3.1.25.1									molecular_function											owl:Class	
GO:0016890	biolink:NamedThing	site-specific endodeoxyribonuclease activity, specific for altered base	Catalysis of the hydrolysis of ester linkages at specific sites within a deoxyribonucleic acid molecule by creating internal breaks.	tmpzr1t_l9r_go_relaxed.owl					EC:3.1.25.-									molecular_function											owl:Class	
GO:0015454	biolink:NamedThing	light-driven active transmembrane transporter activity	Primary active transport of a solute across a membrane, driven by light. Primary active transport is catalysis of the transport of a solute across a membrane, up the solute's concentration gradient, by binding the solute and undergoing a series of conformational changes. Transport works equally well in either direction and is driven by a primary energy source.	tmpzr1t_l9r_go_relaxed.owl	Light absorption-driven transporters|light-driven pumps				TC:3.E									molecular_function											owl:Class	
GO:1903249	biolink:NamedThing	negative regulation of citrulline biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of citrulline biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	downregulation of citrulline anabolism|downregulation of citrulline biosynthetic process|down-regulation of citrulline synthesis|down-regulation of citrulline biosynthesis|down regulation of citrulline anabolism|down-regulation of citrulline biosynthetic process|negative regulation of citrulline synthesis|down regulation of citrulline synthesis|inhibition of citrulline biosynthetic process|downregulation of citrulline biosynthesis|inhibition of citrulline formation|negative regulation of citrulline formation|inhibition of citrulline synthesis|down-regulation of citrulline anabolism|down-regulation of citrulline formation|downregulation of citrulline synthesis|inhibition of citrulline biosynthesis|inhibition of citrulline anabolism|down regulation of citrulline formation|negative regulation of citrulline anabolism|downregulation of citrulline formation|down regulation of citrulline biosynthesis|down regulation of citrulline biosynthetic process|negative regulation of citrulline biosynthesis							rl	2014-08-04T15:24:46Z					biological_process											owl:Class	
GO:0075004	biolink:NamedThing	adhesion of symbiont spore to host	The attachment of a spore of the symbiont to its host via adhesion molecules, general stickiness etc. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	adhesion of symbiont spore to host during symbiotic interaction					Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products from the symbiont involved in this process.								biological_process											owl:Class	
GO:1990851	biolink:NamedThing	Wnt-Frizzled-LRP5/6 complex	A protein complex containing a secreted Wnt protein associated with its receptor, Frizzled (Fz), and co-receptor low density lipoprotein receptor-related protein 5 (LRP5) or LRP6.	tmpzr1t_l9r_go_relaxed.owl	Frizzled-LRP5/6 complex|Wnt.Fz.LRP ternary complex|Fz/Wnt/LRP6 complex|WNT-FZD-LRP6 complex|Wnt-FZD-LRP5/6 trimeric complex|WNT-FZD-LRP5 complex|Wnt receptor complex|Wnt-induced Frizzled-LRP5/6 complex					Given the number of Wnt proteins, Frizzled proteins and LRP proteins, many different trimeric complexes are likely to form.		bf	2015-09-14T15:59:54Z					cellular_component											owl:Class	
GO:0046369	biolink:NamedThing	galactose biosynthetic process	The chemical reactions and pathways resulting in the formation of galactose, the aldohexose galacto-hexose.	tmpzr1t_l9r_go_relaxed.owl	galactose anabolism|galactose synthesis|galactose biosynthesis|galactose formation													biological_process											owl:Class	
GO:0005590	biolink:NamedThing	collagen type VII trimer	A collagen homotrimer of alpha1(VII) chains; type VII collagen triple helices form antiparallel dimer, which in turn associate laterally to form anchoring fibrils that connect type IV collagen in the basal lamina to plaques in the underlying connective tissue. It binds laminin.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0010875	biolink:NamedThing	positive regulation of cholesterol efflux	Any process that increases the frequency, rate or extent of cholesterol efflux. Cholesterol efflux is the directed movement of cholesterol, cholest-5-en-3-beta-ol, out of a cell or organelle.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0045626	biolink:NamedThing	negative regulation of T-helper 1 cell differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of T-helper 1 cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	inhibition of T-helper 1 cell differentiation|negative regulation of T-helper 1 cell development|down regulation of T-helper 1 cell differentiation|down-regulation of T-helper 1 cell differentiation|downregulation of T-helper 1 cell differentiation					Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.								biological_process											owl:Class	
GO:0060946	biolink:NamedThing	cardiac blood vessel endothelial cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a blood vessel endothelial cell of the heart. Blood vessel endothelial cells are thin flattened cells that line the inside surfaces of blood vessels.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-09-29T02:48:55Z					biological_process											owl:Class	
GO:0106049	biolink:NamedThing	regulation of cellular response to osmotic stress	Any process that modulates the frequency, rate or extent of the cellular response to osmotic stress.	tmpzr1t_l9r_go_relaxed.owl								hjd	2017-08-04T14:53:47Z					biological_process											owl:Class	
GO:0098001	biolink:NamedThing	receptor-mediated bacteriophage reversible attachment to host cell	Process by which a bacteriophage, using its tail fibers, spikes or a baseplate component, initially recognizes and binds to its specific receptor on the host cell surface. This process is reversible and allows the release of a bacteriophage without affecting infection.	tmpzr1t_l9r_go_relaxed.owl	phage reversible adsorption|reversible bacteriophage attachment, binding of host cell surface receptor					This process was historically defined by the release, by Waring blending or sonication, by dilution and centrifugation, or by filtration and washing, of infective virions from their complexes with cells, thus contrary to what is observed after irreversible adsorption.		bm						biological_process											owl:Class	
GO:0098671	biolink:NamedThing	adhesion receptor-mediated virion attachment to host cell	The process by which a virion attaches to a host cell by binding to a receptor on the host cell surface that does not mediate or trigger entry into the host cell. This binding is typically reversible and enhances significantly infectivity by concentrating the virus in the vicinity of its entry receptors, or bringing it to an organ in which its target cells are located.	tmpzr1t_l9r_go_relaxed.owl	viral attachment to host adhesion receptor				VZ:3943			dos	2017-01-16T13:22:54Z					biological_process											owl:Class	
GO:0000955	biolink:NamedThing	amino acid catabolic process via Ehrlich pathway	The chemical reactions and pathways involving the catabolism of amino acids to produce alcohols or carboxylic acids containing one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of alcohols, often collectively referred to as fusel alcohols. Depending on the redox state of the cells, carboxylic acid derivatives, sometimes referred to as fusel acids, may be produced instead of alcohols.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0060148	biolink:NamedThing	positive regulation of posttranscriptional gene silencing	Any process that increases the frequency, rate or extent of the inactivation of gene expression by a posttranscriptional mechanism.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0045770	biolink:NamedThing	positive regulation of asymmetric cell division	Any process that activates or increases the frequency, rate or extent of asymmetric cell division.	tmpzr1t_l9r_go_relaxed.owl	upregulation of asymmetric cell division|stimulation of asymmetric cell division|activation of asymmetric cell division|up-regulation of asymmetric cell division|up regulation of asymmetric cell division													biological_process											owl:Class	
GO:0070804	biolink:NamedThing	positive regulation of metula development	Any process that activates or increases the frequency, rate or extent of metula development, a process that leads to the formation of metulae. Metulae are elongated mononucleate cells that bud from the surface of the conidiophore tip.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-07-08T04:38:33Z					biological_process											owl:Class	
GO:0070497	biolink:NamedThing	6-carboxy-5,6,7,8-tetrahydropterin synthase activity	Catalysis of the reaction: 7,8-dihydroneopterin triphosphate + H2O = 6-carboxy-5,6,7,8-tetrahydropterin + triphosphate + acetaldehyde + 2 H+.	tmpzr1t_l9r_go_relaxed.owl					RHEA:27966|MetaCyc:RXN0-5507|EC:4.1.2.50									molecular_function											owl:Class	
GO:0045967	biolink:NamedThing	negative regulation of growth rate	Any process that reduces the rate of growth of all or part of an organism.	tmpzr1t_l9r_go_relaxed.owl	downregulation of growth rate|down regulation of growth rate|inhibition of growth rate|down-regulation of growth rate					Note that this term and its definition depart from the usual conventions for GO 'regulation' process terms; regulation of rate is not usually distinguished from regulation of extent or frequency, but it makes sense to do so for growth regulation.								biological_process											owl:Class	
GO:0048225	biolink:NamedThing	suberin network	An extracellular matrix part that consists of fatty acid-derived polymers, including both aromatic and aliphatic components. The suberin network is found in specialized plant cell walls, where it is laid down between the primary wall and plasma membrane, forms protective and wound-healing layers, and provides a water-impermeable diffusion barrier.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0062165	biolink:NamedThing	positive regulation of pseudohyphal septin ring assembly	Any process that increases the rate, frequency or extent of pseudohyphal septin ring formation.	tmpzr1t_l9r_go_relaxed.owl								dph	2019-11-07T15:55:38Z					biological_process											owl:Class	
GO:0044353	biolink:NamedThing	micropinosome	A membrane-bounded, uncoated intracellular vesicle formed by the process of micropinocytosis.	tmpzr1t_l9r_go_relaxed.owl								jl	2011-08-11T10:51:27Z					cellular_component											owl:Class	
GO:0044352	biolink:NamedThing	pinosome	A membrane-bounded, uncoated intracellular vesicle formed by the process of pinocytosis.	tmpzr1t_l9r_go_relaxed.owl	pinocytic vesicle				NIF_Subcellular:sao1925368674			jl	2011-08-11T10:51:13Z					cellular_component											owl:Class	
GO:1990148	biolink:NamedThing	glutamate dehydrogenase complex	A homomeric protein complex that possesses glutamate dehydrogenase activity. This complex is evolutionarily conserved except that the number of homoprotomers per complex varies.	tmpzr1t_l9r_go_relaxed.owl	glutamate dehydrogenase (NADP+) complex|glutamic dehydrogenase complex|NAD(P)H-dependent glutamate dehydrogenase complex|L-glutamic acid dehydrogenase complex|L-glutamate dehydrogenase complex|glutamic acid dehydrogenase complex|dehydrogenase, glutamate (nicotinamide adenine dinucleotide (phosphate)) complex|L-glutamate:NADP+ oxidoreductase (deaminating) complex|NAD(P)-glutamate dehydrogenase complex							pr	2013-07-26T10:14:15Z					cellular_component											owl:Class	
GO:0050304	biolink:NamedThing	nitrous-oxide reductase activity	Catalysis of the reaction: H(2)O + 2 cytochrome c + nitrogen = 2 reduced cytochrome c + nitrous oxide.	tmpzr1t_l9r_go_relaxed.owl	nitrogen:(acceptor) oxidoreductase (N2O-forming)|nitrous oxide reductase activity|N2O reductase activity|nitrogen:acceptor oxidoreductase (N2O-forming)				RHEA:43108|EC:1.7.2.4|KEGG_REACTION:R02804|MetaCyc:RXN-12130									molecular_function											owl:Class	
GO:0000772	biolink:NamedThing	mating pheromone activity	The activity of binding to and activating specific cell surface receptors, thereby inducing a behavioral or physiological response(s) from a responding organism or cell that leads to the transfer or union of genetic material between organisms or cells. The mating pheromone can either be retained on the cell surface or secreted.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0106216	biolink:NamedThing	positive regulation of vesicle fusion with Golgi apparatus	Any process that activates or increases the frequency, rate or extent of vesicle fusion with Golgi apparatus.	tmpzr1t_l9r_go_relaxed.owl								hjd	2019-06-27T15:20:59Z					biological_process											owl:Class	
GO:1901497	biolink:NamedThing	response to diphenyl ether	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diphenyl ether stimulus.	tmpzr1t_l9r_go_relaxed.owl								tt	2012-10-16T14:58:08Z					biological_process											owl:Class	
GO:0030891	biolink:NamedThing	VCB complex	A protein complex that possesses ubiquitin ligase activity; the complex is usually pentameric; for example, in mammals the subunits are pVHL, elongin B, elongin C, cullin-2 (Cul2), and Rbx1.	tmpzr1t_l9r_go_relaxed.owl	VHL complex|von Hippel-Lindau tumor suppressor complex|pVHL-elongin C-elongin B complex													cellular_component											owl:Class	
GO:0106024	biolink:NamedThing	negative regulation of pupariation	Any process that stops, prevents or reduces the rate of onset of pupariation.	tmpzr1t_l9r_go_relaxed.owl								hjd	2017-05-24T19:35:29Z					biological_process											owl:Class	
GO:1903172	biolink:NamedThing	cellular carbon dioxide homeostasis	Any biological process involved in the maintenance of an internal steady state of carbon dioxide at the level of the cell.	tmpzr1t_l9r_go_relaxed.owl								mr	2014-07-11T20:58:30Z					biological_process											owl:Class	
GO:0000471	biolink:NamedThing	endonucleolytic cleavage in 3'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	Endonucleolytic cleavage within the 3'-External Transcribed Spacer (ETS) of a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, the 5.8S rRNA, and the Large Subunit (LSU) rRNA in that order from 5' to 3' along the primary transcript. In S. cerevisiae, endonucleolytic cleavage within the 3'-ETS of the pre-RNA, which may occur cotranscriptionally, is the first step in rRNA processing, and initiates a cascade of subsequent processing and modification events.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0016442	biolink:NamedThing	RISC complex	A ribonucleoprotein complex that contains members of the Argonaute family of proteins, small interfering RNAs (siRNAs) or microRNAs (miRNAs), and miRNA or siRNA-complementary mRNAs, in addition to a number of accessory factors. The RISC complex is involved in posttranscriptional repression of gene expression through downregulation of translation or induction of mRNA degradation.	tmpzr1t_l9r_go_relaxed.owl	RNA-induced silencing complex|micro-ribonucleoprotein complex|miRNP complex				Wikipedia:RNA-induced_silencing_complex							GO:0035068		cellular_component											owl:Class	
GO:0031332	biolink:NamedThing	RNAi effector complex	Any protein complex that mediates the effects of small interfering RNAs on gene expression. Most known examples contain one or more members of the Argonaute family of proteins.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0060766	biolink:NamedThing	negative regulation of androgen receptor signaling pathway	Any process that decreases the rate, frequency, or extent of the androgen receptor signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of androgen receptor signalling pathway							dph	2009-07-06T11:09:36Z					biological_process											owl:Class	
GO:0061292	biolink:NamedThing	canonical Wnt signaling pathway involved in mesonephros development	The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes that contributes to the progression of the mesonephros over time. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes.	tmpzr1t_l9r_go_relaxed.owl	canonical Wnt receptor signaling pathway involved in mesonephros development|canonical Wnt-activated signaling pathway involved in mesonephros development|canonical Wnt receptor signalling pathway involved in mesonephros development							dph	2010-09-03T12:23:09Z					biological_process											owl:Class	
GO:0003176	biolink:NamedThing	aortic valve development	The progression of the aortic valve over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-10-08T11:18:55Z					biological_process											owl:Class	
GO:0002602	biolink:NamedThing	negative regulation of antigen processing and presentation of polysaccharide antigen via MHC class II	Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of polysaccharide antigen via MHC class II.	tmpzr1t_l9r_go_relaxed.owl	downregulation of antigen processing and presentation of polysaccharide antigen via MHC class II|down-regulation of antigen processing and presentation of polysaccharide antigen via MHC class II|negative regulation of polysaccharide antigen processing and presentation via MHC class II|down regulation of antigen processing and presentation of polysaccharide antigen via MHC class II|inhibition of antigen processing and presentation of polysaccharide antigen via MHC class II													biological_process											owl:Class	
GO:0061577	biolink:NamedThing	calcium ion transmembrane transport via high voltage-gated calcium channel	A process in which a calcium ion is transported from one side of a membrane to the other by means of a high voltage-gated calcium channel.	tmpzr1t_l9r_go_relaxed.owl	generation of L-type calcium current							dph	2013-11-15T16:20:27Z					biological_process											owl:Class	
GO:1902959	biolink:NamedThing	regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process	Any process that modulates the frequency, rate or extent of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolism|regulation of aspartic protease activity involved in amyloid precursor protein breakdown|regulation of aspartic endopeptidase activity involved in APP catabolism|regulation of aspartic endopeptidase activity involved in amyloid precursor protein degradation|regulation of aspartic-type endopeptidase activity involved in APP catabolic process|regulation of aspartic endopeptidase activity involved in APP catabolic process|regulation of aspartate protease activity involved in amyloid precursor protein breakdown|regulation of aspartate protease activity involved in amyloid precursor protein degradation|regulation of aspartyl protease activity involved in APP catabolism|regulation of aspartyl protease activity involved in amyloid precursor protein catabolism|regulation of aspartyl protease activity involved in amyloid precursor protein breakdown|regulation of aspartate protease activity involved in amyloid precursor protein catabolism|regulation of aspartyl protease activity involved in APP catabolic process|regulation of carboxyl protease activity involved in APP catabolic process|regulation of aspartic protease activity involved in amyloid precursor protein catabolism|regulation of aspartic protease activity involved in amyloid precursor protein catabolic process|regulation of aspartic endopeptidase activity involved in amyloid precursor protein breakdown|regulation of aspartic protease activity involved in APP catabolism|regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein breakdown|regulation of aspartate protease activity involved in APP catabolism|regulation of aspartic protease activity involved in amyloid precursor protein degradation|regulation of carboxyl protease activity involved in amyloid precursor protein degradation|regulation of aspartyl protease activity involved in amyloid precursor protein degradation|regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein degradation|regulation of carboxyl protease activity involved in amyloid precursor protein breakdown|regulation of aspartic protease activity involved in APP catabolic process|regulation of aspartic endopeptidase activity involved in amyloid precursor protein catabolic process|regulation of aspartate protease activity involved in amyloid precursor protein catabolic process|regulation of aspartic endopeptidase activity involved in amyloid precursor protein catabolism|regulation of carboxyl protease activity involved in amyloid precursor protein catabolism|regulation of aspartic-type endopeptidase activity involved in APP catabolism|regulation of carboxyl protease activity involved in APP catabolism|regulation of aspartyl protease activity involved in amyloid precursor protein catabolic process|regulation of carboxyl protease activity involved in amyloid precursor protein catabolic process|regulation of aspartate protease activity involved in APP catabolic process							sjp	2014-05-06T09:07:04Z					biological_process											owl:Class	
GO:0051559	biolink:NamedThing	phlobaphene biosynthetic process	The chemical reactions and pathways resulting in the formation of phlobaphenes, red pigments with oligomeric or polymeric structure derived from the flavonoid intermediate flavan-4-ols.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0007390	biolink:NamedThing	germ-band shortening	The spreading of the amnioserosa from its compressed state to cover the whole of the dorsal surface. Initiating in the thorax and spreading posteriorly, it is accompanied by the transition from a parasegmental to segmental division of the embryo.	tmpzr1t_l9r_go_relaxed.owl	germ-band retraction													biological_process											owl:Class	
GO:1904560	biolink:NamedThing	response to diphenidol	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diphenidol stimulus.	tmpzr1t_l9r_go_relaxed.owl								mr	2015-08-14T16:09:31Z					biological_process											owl:Class	
GO:0072297	biolink:NamedThing	specification of metanephric proximal tubule identity	The process in which the proximal tubule of the metanephric nephron acquires its identity.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-04-09T04:08:20Z					biological_process											owl:Class	
GO:1903185	biolink:NamedThing	L-dopa biosynthetic process	The chemical reactions and pathways resulting in the formation of L-dopa.	tmpzr1t_l9r_go_relaxed.owl	L-dopa biosynthesis|L-dopa formation|L-dopa synthesis|L-dopa anabolism							bf	2014-07-14T15:06:06Z					biological_process											owl:Class	
GO:0046687	biolink:NamedThing	response to chromate	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chromate stimulus.	tmpzr1t_l9r_go_relaxed.owl	chromate sensitivity/resistance													biological_process											owl:Class	
GO:0052063	biolink:NamedThing	induction by symbiont of defense-related host nitric oxide production	The activation by a symbiont of the production of nitric oxide as part of the defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	positive regulation by organism of defense-related host NO production|up-regulation by symbiont of defense-related host nitric oxide production|induction by organism of defense-related host NO production|stimulation by symbiont of defense-related host nitric oxide production|up regulation by symbiont of defense-related host nitric oxide production|activation by organism of defense-related host NO production|upregulation by symbiont of defense-related host nitric oxide production|induction by organism of defense-related nitric oxide production in other organism involved in symbiotic interaction|positive regulation by organism of defense-related nitric oxide production in other organism involved in symbiotic interaction|activation by symbiont of defense-related host nitric oxide production|positive regulation by symbiont of defense-related host nitric oxide production|activation by organism of defense-related host nitric oxide production											GO:0052263|GO:0052345|GO:0052347		biological_process											owl:Class	
GO:1905357	biolink:NamedThing	negative regulation of snRNA pseudouridine synthesis	Any process that stops, prevents or reduces the frequency, rate or extent of snRNA pseudouridine synthesis.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of snRNA pseudouridine synthesis|down regulation of snRNA pseudouridine synthesis|inhibition of snRNA pseudouridine synthesis|downregulation of snRNA pseudouridine synthesis							se	2016-08-09T19:12:35Z					biological_process											owl:Class	
GO:0001512	biolink:NamedThing	dihydronicotinamide riboside quinone reductase activity	Catalysis of the reaction: 1-(beta-D-ribofuranosyl)-1,4-dihydronicotinamide + a quinone = 1-(beta-D-ribofuranosyl)nicotinamide + a hydroquinone.	tmpzr1t_l9r_go_relaxed.owl	ribosyldihydronicotinamide dehydrogenase (quinone) activity|NRH:quinone oxidoreductase 2 activity|NQO2|QR2 activity|NQO(2) activity|quinone reductase 2 activity|N-ribosyldihydronicotinamide dehydrogenase (quinone) activity	https://github.com/geneontology/go-ontology/issues/21412			RHEA:12364|Reactome:R-HSA-8936519|MetaCyc:1.10.99.2-RXN|EC:1.10.5.1	Formerly EC:1.10.99.2.								molecular_function											owl:Class	
GO:0008811	biolink:NamedThing	chloramphenicol O-acetyltransferase activity	Catalysis of the reaction: chloramphenicol + acetyl-CoA = chloramphenicol 3-acetate + CoA.	tmpzr1t_l9r_go_relaxed.owl	chloramphenicol transacetylase activity|chloramphenicol acetylase activity|chloramphenicol acetyltransferase activity|CAT III|CAT I|acetyl-CoA:chloramphenicol 3-O-acetyltransferase activity|CAT II				EC:2.3.1.28|RHEA:18421|KEGG_REACTION:R03065|MetaCyc:CHLORAMPHENICOL-O-ACETYLTRANSFERASE-RXN									molecular_function											owl:Class	
GO:0017013	biolink:NamedThing	protein flavinylation	The addition of a flavin group to a protein amino acid.	tmpzr1t_l9r_go_relaxed.owl	protein amino acid flavinylation													biological_process											owl:Class	
GO:0014909	biolink:NamedThing	smooth muscle cell migration	The orderly movement of a smooth muscle cell from one site to another, often during the development of a multicellular organism.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1990119	biolink:NamedThing	RNA helicase inhibitor activity	Binds to and stops, prevents or reduces the activity of an RNA helicase.	tmpzr1t_l9r_go_relaxed.owl	ATP-dependent RNA helicase inhibitor activity							rb	2013-06-11T21:14:38Z					molecular_function											owl:Class	
GO:0050829	biolink:NamedThing	defense response to Gram-negative bacterium	Reactions triggered in response to the presence of a Gram-negative bacterium that act to protect the cell or organism.	tmpzr1t_l9r_go_relaxed.owl	defence response to Gram-negative bacteria|Gram-negative antibacterial peptide activity|defence response to Gram-negative bacterium|defense response to Gram-negative bacteria													biological_process											owl:Class	
GO:0004990	biolink:NamedThing	oxytocin receptor activity	Combining with oxytocin to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0039636	biolink:NamedThing	suppression by virus of host cell wall biogenesis	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of cell wall biogenesis in the host organism. Cell wall biogenesis includes the biosynthesis of constituent macromolecules, and the assembly and arrangement of these constituent parts.	tmpzr1t_l9r_go_relaxed.owl								bf	2012-08-10T15:04:12Z					biological_process											owl:Class	
GO:0033464	biolink:NamedThing	GGG codon-amino acid adaptor activity	A triplet codon-amino acid adaptor activity that recognizes a GGG codon.	tmpzr1t_l9r_go_relaxed.owl	glycine tRNA					Note that in the standard genetic code, GGG codes for glycine.								molecular_function											owl:Class	
GO:0035752	biolink:NamedThing	lysosomal lumen pH elevation	Any process that increases the pH of the lysosomal lumen, measured by the concentration of the hydrogen ion.	tmpzr1t_l9r_go_relaxed.owl	lysosome pH elevation							bf	2011-03-23T10:24:24Z					biological_process											owl:Class	
GO:0044688	biolink:NamedThing	7,8-dihydro-D-neopterin 2',3'-cyclic phosphate phosphodiesterase activity	Catalysis of the reaction: 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate + H2O = 7,8-dihydroneopterin 3'-phosphate + H+.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-08-15T14:28:30Z					molecular_function											owl:Class	
GO:0106146	biolink:NamedThing	sideretin biosynthesis	The chemical reactions and pathways resulting in the formation of sideretin.	tmpzr1t_l9r_go_relaxed.owl								hjd	2018-09-07T18:31:30Z					biological_process											owl:Class	
GO:0047062	biolink:NamedThing	trans-acenaphthene-1,2-diol dehydrogenase activity	Catalysis of the reaction: (+-)-trans-acenaphthene-1,2-diol + 2 NADP(+) = acenaphthene-1,2-dione + 2 H(+) + 2 NADPH.	tmpzr1t_l9r_go_relaxed.owl	trans-1,2-acenaphthenediol dehydrogenase activity|(+-)-trans-acenaphthene-1,2-diol:NADP+ oxidoreductase activity				RHEA:22184|KEGG_REACTION:R04059|MetaCyc:1.10.1.1-RXN|EC:1.10.1.1									molecular_function											owl:Class	
GO:0016680	biolink:NamedThing	oxidoreductase activity, acting on diphenols and related substances as donors, NAD or NADP as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which a diphenol, or related compound, acts as a hydrogen or electron donor and reduces NAD or NADP.	tmpzr1t_l9r_go_relaxed.owl					EC:1.10.1.-									molecular_function											owl:Class	
GO:0045669	biolink:NamedThing	positive regulation of osteoblast differentiation	Any process that activates or increases the frequency, rate or extent of osteoblast differentiation.	tmpzr1t_l9r_go_relaxed.owl	activation of osteoblast differentiation|stimulation of osteoblast differentiation|up regulation of osteoblast differentiation|upregulation of osteoblast differentiation|up-regulation of osteoblast differentiation													biological_process											owl:Class	
GO:0060422	biolink:NamedThing	peptidyl-dipeptidase inhibitor activity	Binds to and stops, prevents or reduces the activity of a peptidyl-dipeptidase. Peptidyl-dipeptidase activity catalyzes the release of C-terminal dipeptides from a polypeptide chain.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0004820	biolink:NamedThing	glycine-tRNA ligase activity	Catalysis of the reaction: ATP + glycine + tRNA(Gly) = AMP + diphosphate + glycyl-tRNA(Gly).	tmpzr1t_l9r_go_relaxed.owl	glycyl-transfer RNA synthetase activity|glycyl-tRNA synthetase activity|glycyl translase activity|glycyl-transfer ribonucleate synthetase activity|glycine:tRNAGly ligase (AMP-forming) activity|glycyl-transfer ribonucleic acid synthetase activity				MetaCyc:GLYCINE--TRNA-LIGASE-RXN|RHEA:16013|EC:6.1.1.14|Reactome:R-HSA-380240|Reactome:R-HSA-380048									molecular_function											owl:Class	
GO:0102296	biolink:NamedThing	4,5-9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase activity	Catalysis of the reaction: (1E,2Z)-3-hydroxy-5,9,17-trioxo-4,5:9,10-disecoandrosta-1(10),2-dien-4-oate + H2O <=> 9,17-dioxo-1,2,3,4,10,19-hexanorandrostan-5-oate + (2Z,4Z)-2-hydroxyhexa-2,4-dienoate + H+.	tmpzr1t_l9r_go_relaxed.owl					EC:3.7.1.17|MetaCyc:RXN-12718|RHEA:32035									molecular_function											owl:Class	
GO:0022874	biolink:NamedThing	protein-N(PI)-phosphohistidine-cellobiose phosphotransferase system transporter activity	Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + cellobiose(out) = protein histidine + cellobiose phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.	tmpzr1t_l9r_go_relaxed.owl	cellobiose PTS transporter activity													molecular_function											owl:Class	
GO:0030327	biolink:NamedThing	prenylated protein catabolic process	The chemical reactions and pathways resulting in the breakdown of prenylated proteins.	tmpzr1t_l9r_go_relaxed.owl	prenylated protein catabolism|prenylated protein breakdown|prenylated protein degradation													biological_process											owl:Class	
GO:0019650	biolink:NamedThing	glycolytic fermentation to butanediol	The anaerobic chemical reactions and pathways resulting in the breakdown of glucose into butanediol; effected by some members of the Enterobacteriaceae, e.g. Enterobacter, Erwinia, Klebsiella, and Serratia.	tmpzr1t_l9r_go_relaxed.owl	butanediol fermentation|glucose catabolic process to butanediol|glucose fermentation to butanediol				MetaCyc:P125-PWY|Wikipedia:Butanediol_fermentation							GO:0030646		biological_process											owl:Class	
GO:0034953	biolink:NamedThing	perillyl-CoA hydratase activity	Catalysis of the reaction: perillyl-CoA + H2O = 2-hydroxy-4-isopropenylcyclohexane-1-carboxyl-CoA.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r1002									molecular_function											owl:Class	
GO:1903855	biolink:NamedThing	positive regulation of stress response to copper ion	Any process that activates or increases the frequency, rate or extent of stress response to copper ion.	tmpzr1t_l9r_go_relaxed.owl	up regulation of stress response to copper ion|activation of stress response to copper ion|up-regulation of response to copper toxicity|up regulation of response to copper ion stress|up regulation of response to copper toxicity|activation of response to copper toxicity|upregulation of stress response to copper ion|positive regulation of response to copper ion stress|positive regulation of response to copper toxicity|up-regulation of stress response to copper ion|activation of response to copper ion stress|up-regulation of response to copper ion stress|upregulation of response to copper toxicity|upregulation of response to copper ion stress							kmv	2015-01-29T20:15:42Z					biological_process											owl:Class	
GO:0052628	biolink:NamedThing	4-hydroxybenzoate amino acid synthetase activity	Catalysis of the reaction: 4-hydroxybenzoate + ATP + amino acid = 4-hydroxybenzoyl amino acid conjugate + AMP + diphosphate.	tmpzr1t_l9r_go_relaxed.owl	p-hydroxybenzoate amino acid synthetase activity|p-hydroxybenzoyl amino acid synthetase activity|4-hydroxybenzoyl amino acid synthetase activity|4HBA amino acid synthetase activity													molecular_function											owl:Class	
GO:0047209	biolink:NamedThing	coniferyl-alcohol glucosyltransferase activity	Catalysis of the reaction: coniferyl alcohol + UDP-D-glucose = coniferin + UDP.	tmpzr1t_l9r_go_relaxed.owl	UDPglucose:coniferyl-alcohol 4'-beta-D-glucosyltransferase activity|uridine diphosphoglucose-coniferyl alcohol glucosyltransferase activity|UDP-glucose coniferyl alcohol glucosyltransferase activity|UDP-glucose:coniferyl-alcohol 4'-beta-D-glucosyltransferase activity				RHEA:23944|EC:2.4.1.111|MetaCyc:2.4.1.111-RXN									molecular_function											owl:Class	
GO:0060101	biolink:NamedThing	negative regulation of phagocytosis, engulfment	Any process that stops, prevents, or reduces the frequency, rate or extent of the internalization of bacteria, immune complexes and other particulate matter or of an apoptotic cell by phagocytosis.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0005604	biolink:NamedThing	basement membrane	A collagen-containing extracellular matrix consisting of a thin layer of dense material found in various animal tissues interposed between the cells and the adjacent connective tissue. It consists of the basal lamina plus an associated layer of reticulin fibers.	tmpzr1t_l9r_go_relaxed.owl	lamina densa|basement lamina|basal lamina				Wikipedia:Basement_membrane	Note that this term has no relationship to 'membrane ; GO:0016020' because the basement membrane is not a lipid bilayer.						GO:0005605|GO:0008003		cellular_component											owl:Class	
GO:1903545	biolink:NamedThing	cellular response to butyrate	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a butyrate stimulus.	tmpzr1t_l9r_go_relaxed.owl								mr	2014-10-17T13:57:35Z					biological_process											owl:Class	
GO:0033501	biolink:NamedThing	galactose homeostasis	A homeostatic process involved in the maintenance of an internal steady state of galactose within an organism or cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0018139	biolink:NamedThing	peptide cross-linking via L-phenylalanine thiazolecarboxylic acid	The chemical reactions and pathways resulting in the formation of a peptidyl cysteine-peptidyl phenylalanine cross-link by the condensation of a cysteine thiol with the carbonyl of the preceding residue and alpha-beta dehydrogenation.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0243									biological_process											owl:Class	
GO:0010789	biolink:NamedThing	meiotic sister chromatid cohesion involved in meiosis I	The cell cycle process in which sister chromatids of a replicated chromosome are joined along the entire length of the chromosome during meiosis I.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0038037	biolink:NamedThing	G protein-coupled receptor dimeric complex	A protein complex that contains two G protein-coupled receptors.	tmpzr1t_l9r_go_relaxed.owl	G-protein coupled receptor dimer|G-protein coupled receptor dimeric complex|GPCR dimer							bf	2011-11-02T04:42:44Z					cellular_component											owl:Class	
GO:1903268	biolink:NamedThing	positive regulation of ornithine catabolic process	Any process that activates or increases the frequency, rate or extent of ornithine catabolic process.	tmpzr1t_l9r_go_relaxed.owl	upregulation of ornithine catabolic process|upregulation of ornithine breakdown|activation of ornithine breakdown|up-regulation of ornithine breakdown|up regulation of ornithine catabolism|up regulation of ornithine degradation|up-regulation of ornithine catabolism|positive regulation of ornithine catabolism|activation of ornithine degradation|up-regulation of ornithine catabolic process|activation of ornithine catabolic process|upregulation of ornithine catabolism|positive regulation of ornithine degradation|activation of ornithine catabolism|up-regulation of ornithine degradation|up regulation of ornithine breakdown|up regulation of ornithine catabolic process|upregulation of ornithine degradation|positive regulation of ornithine breakdown							bhm	2014-08-08T08:29:50Z					biological_process											owl:Class	
GO:1901151	biolink:NamedThing	vistamycin catabolic process	The chemical reactions and pathways resulting in the breakdown of vistamycin.	tmpzr1t_l9r_go_relaxed.owl	vistamycin catabolism|ribostamycin degradation|ribostamycin catabolism|vistamycin degradation|ribostamycin breakdown|vistamycin breakdown|ribostamycin catabolic process							yaf	2012-07-17T04:27:07Z					biological_process											owl:Class	
GO:0097300	biolink:NamedThing	programmed necrotic cell death	A necrotic cell death process that results from the activation of endogenous cellular processes, such as signaling involving death domain receptors or Toll-like receptors.	tmpzr1t_l9r_go_relaxed.owl	programmed cell death by necrosis|regulated necrosis					This term may be used when annotating instances of programmed cell death characterized by necrotic morphology where the involvement of RIPK1 and/or RIPK3 is not shown. See PMID:23818611 for some examples.		pr	2012-05-04T03:03:39Z					biological_process											owl:Class	
GO:0070265	biolink:NamedThing	necrotic cell death	A type of cell death that is morphologically characterized by an increasingly translucent cytoplasm, swelling of organelles, minor ultrastructural modifications of the nucleus (specifically, dilatation of the nuclear membrane and condensation of chromatin into small, irregular, circumscribed patches) and increased cell volume (oncosis), culminating in the disruption of the plasma membrane and subsequent loss of intracellular contents. Necrotic cells do not fragment into discrete corpses as their apoptotic counterparts do. Moreover, their nuclei remain intact and can aggregate and accumulate in necrotic tissues.	tmpzr1t_l9r_go_relaxed.owl	cellular necrosis|necrosis					Note that the word necrosis has been widely used in earlier literature to describe forms of cell death which are now known by more precise terms, such as apoptosis. Necrosis can occur in a regulated fashion, involving a precise sequence of signals; in this case, consider annotating to GO:0097300 'programmed necrotic cell death' or to its more specific child GO:0070266 'necroptotic process'.								biological_process											owl:Class	
GO:0070522	biolink:NamedThing	ERCC4-ERCC1 complex	A heterodimeric nucleotide-excision repair complex that has endonuclease activity specific for bubble structures characteristic of certain DNA lesions. The subunits are known as XPF/ERCC4 and ERCC1 in mammals, and Rad1p and Rad10p in S. cerevisiae.	tmpzr1t_l9r_go_relaxed.owl	Rad1-Rad10 complex|XPF-ERCC1 complex					Note that process and function information are included in the term and definition for the purpose of describing and distinguishing the complex.								cellular_component											owl:Class	
GO:0000109	biolink:NamedThing	nucleotide-excision repair complex	Any complex formed of proteins that act in nucleotide-excision repair.	tmpzr1t_l9r_go_relaxed.owl	UvrB-UvrC complex|UvrBC complex					Note that process information is included in the term and definition for the purpose of describing and distinguishing the complex.								cellular_component											owl:Class	
GO:0019711	biolink:NamedThing	peptidyl-beta-carboxyaspartic acid biosynthetic process from peptidyl-aspartic acid	The chemical reactions and pathways resulting in the formation of peptidyl-beta-carboxyaspartic acid from other compounds, including peptidyl-aspartic acid.	tmpzr1t_l9r_go_relaxed.owl	peptidyl-beta-carboxyaspartic acid formation from peptidyl-aspartic acid|peptidyl-beta-carboxyaspartic acid anabolism from peptidyl-aspartic acid|peptidyl-beta-carboxyaspartic acid synthesis from peptidyl-aspartic acid													biological_process											owl:Class	
GO:0009316	biolink:NamedThing	3-isopropylmalate dehydratase complex	A heterodimeric enzyme complex composed of subunits leuC and leuD. Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.	tmpzr1t_l9r_go_relaxed.owl	isopropylmalate isomerase complex				MetaCyc:3-ISOPROPYLMALISOM-CPLX	See also the molecular function term '3-isopropylmalate dehydratase activity ; GO:0003861'.								cellular_component											owl:Class	
GO:0099635	biolink:NamedThing	voltage-gated calcium channel activity involved in positive regulation of presynaptic cytosolic calcium levels	Positive regulation of presynaptic cytosolic calcium ion concentrations via the directed movement of calcium ions across the plasma-membrane into the cytosol via the action of voltage-gated calcium ion channels.  This is the first step in synaptic transmission.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0099626	biolink:NamedThing	voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels	Regulation of presynaptic cytosolic calcium ion concentrations via the action of voltage-gated calcium ion channels.	tmpzr1t_l9r_go_relaxed.owl	voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels													molecular_function											owl:Class	
GO:0140274	biolink:NamedThing	repair of kinetochore microtubule attachment defect	The cell cycle process where kinetochore microtubule attachment defects are corrected.	tmpzr1t_l9r_go_relaxed.owl	repair of kinetochore microtubule attachment defects|correction of kinetochore microtubule attachment defects							pg	2018-10-01T11:30:19Z					biological_process											owl:Class	
GO:0030513	biolink:NamedThing	positive regulation of BMP signaling pathway	Any process that activates or increases the frequency, rate or extent of BMP signaling pathway activity.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of decapentaplegic signaling pathway|positive regulation of BMP signalling pathway|activation of BMP signaling pathway|positive regulation of decapentaplegic receptor signaling pathway|positive regulation of bone morphogenetic protein signalling pathway|up-regulation of BMP signaling pathway|upregulation of BMP signaling pathway|stimulation of BMP signaling pathway|positive regulation of bone morphogenetic protein signaling pathway|positive regulation of decapentaplegic receptor signalling pathway|positive regulation of BMP receptor signaling pathway|up regulation of BMP signaling pathway							tb	2009-11-13T10:50:41Z			GO:0090098		biological_process											owl:Class	
GO:0062129	biolink:NamedThing	chitin-based extracellular matrix	Any constituent part of a chitin-based noncellular, hardened, or membranous extracellular matrix secreted from the apical surface of an epithelial sheet.	tmpzr1t_l9r_go_relaxed.owl	chitin-based ECM							dph	2019-06-13T12:57:13Z					cellular_component											owl:Class	
GO:0030784	biolink:NamedThing	3'-hydroxy-N-methyl-(S)-coclaurine 4'-O-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + 3'-hydroxy-N-methyl-(S)-coclaurine = S-adenosyl-L-homocysteine + (S)-reticuline.	tmpzr1t_l9r_go_relaxed.owl	S-adenosyl-L-methionine:3'-hydroxy-N-methyl-(S)-coclaurine 4'-O-methyltransferase activity				MetaCyc:2.1.1.116-RXN|RHEA:17789|EC:2.1.1.116									molecular_function											owl:Class	
GO:1901295	biolink:NamedThing	regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment	Any process that modulates the frequency, rate or extent of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment.	tmpzr1t_l9r_go_relaxed.owl	regulation of canonical Wnt receptor signalling pathway involved in cardiac muscle cell fate commitment|regulation of canonical Wnt receptor signaling pathway involved in cardiac muscle cell fate commitment|regulation of canonical Wnt-activated signaling pathway involved in cardiac muscle cell fate commitment							vk	2012-08-21T09:06:32Z					biological_process											owl:Class	
GO:0045199	biolink:NamedThing	maintenance of epithelial cell apical/basal polarity	The maintenance of the apicobasal polarity of an epithelial cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0035090	biolink:NamedThing	maintenance of apical/basal cell polarity	Retaining the established polarization of a cell along its apical/basal axis.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0018442	biolink:NamedThing	peptidyl-glutamic acid esterification	The addition of an ester group to a glutamic acid residue in a protein.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0036276	biolink:NamedThing	response to antidepressant	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antidepressant stimulus, a mood-stimulating drug.	tmpzr1t_l9r_go_relaxed.owl						Note that this term is in the subset of terms that should not be used for direct manual annotation of gene products. It was created to be used for cross-referencing by other ontologies. Direct annotations to this term may be amended during annotation QC.		bf	2012-07-09T02:12:44Z					biological_process											owl:Class	
GO:0033023	biolink:NamedThing	mast cell homeostasis	The process of regulating the proliferation and elimination of mast cells such that the total number of mast cells within a whole or part of an organism is stable over time in the absence of an outside stimulus.	tmpzr1t_l9r_go_relaxed.owl						Note that this term represents the return of mast cell levels to stable numbers following an immune response as well as the proliferation and elimination of mast cells required to maintain stable numbers in the absence of an outside stimulus.								biological_process											owl:Class	
GO:0070719	biolink:NamedThing	alphaPDGFR-PLC-gamma-1-PI3K-SHP-2 complex	A protein complex that contains the platelet-derived growth factor alpha receptor (alphaPDGFR; PDGFRA), phospholipase C-gamma-1 (PLC-gamma-1), phosphatidylinositol 3-kinase (PI3K) and the adaptor protein SHP-2, and is involved signaling via the PDGFR signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	PDGFRA-PLC-gamma-1-PI3K-SHP-2 complex, PDGF stimulated							mah	2009-06-10T05:04:20Z					cellular_component											owl:Class	
GO:0046012	biolink:NamedThing	positive regulation of oskar mRNA translation	Any process that activates or increases the frequency, rate or extent of oskar mRNA translation.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of oskar mRNA translation|upregulation of oskar mRNA translation|up regulation of oskar mRNA translation|stimulation of oskar mRNA translation|activation of oskar mRNA translation													biological_process											owl:Class	
GO:1900868	biolink:NamedThing	sarcinapterin biosynthetic process	The chemical reactions and pathways resulting in the formation of sarcinapterin.	tmpzr1t_l9r_go_relaxed.owl	sarcinapterin formation|sarcinapterin synthesis|sarcinapterin biosynthesis|sarcinapterin anabolism							tt	2012-06-12T04:34:33Z					biological_process											owl:Class	
GO:0140354	biolink:NamedThing	lipid import into cell	The directed movement of a lipid from outside of a cell into a cell. This may occur via transport across the plasma membrane or via endocytosis.	tmpzr1t_l9r_go_relaxed.owl	lipid uptake							pg	2019-05-22T11:38:15Z					biological_process											owl:Class	
GO:0050401	biolink:NamedThing	xylonate dehydratase activity	Catalysis of the reaction: D-xylonate = 2-dehydro-3-deoxy-D-arabinonate + H(2)O.	tmpzr1t_l9r_go_relaxed.owl	D-xylo-aldonate dehydratase activity|D-xylonate hydro-lyase (2-dehydro-3-deoxy-D-xylonate-forming)|D-xylonate hydro-lyase activity|D-xylonate dehydratase activity				MetaCyc:XYLONATE-DEHYDRATASE-RXN|RHEA:19157|KEGG_REACTION:R02429|EC:4.2.1.82									molecular_function											owl:Class	
GO:2000894	biolink:NamedThing	cellotriose catabolic process	The chemical reactions and pathways resulting in the breakdown of a cellotriose.	tmpzr1t_l9r_go_relaxed.owl	cellotriose catabolism							jl	2011-07-28T02:02:47Z					biological_process											owl:Class	
GO:2000893	biolink:NamedThing	cellotriose metabolic process	The chemical reactions and pathways involving a cellotriose.	tmpzr1t_l9r_go_relaxed.owl	cellotriose metabolism							jl	2011-07-28T02:02:44Z					biological_process											owl:Class	
GO:0010289	biolink:NamedThing	homogalacturonan biosynthetic process	The chemical reactions and pathways resulting in the formation of the pectidic homogalacturonan, characterized by a backbone of (1->4)-linked alpha-D-GalpA residues that can be methyl-esterified at C-6 and carry acetyl groups on O-2 and O-3.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:PWY-1061									biological_process											owl:Class	
GO:0052325	biolink:NamedThing	cell wall pectin biosynthetic process	The chemical reactions and pathways resulting in the formation of pectin, a polymer containing a backbone of alpha-1,4-linked D-galacturonic acid residues, as part of the organization and biogenesis of the cell wall.	tmpzr1t_l9r_go_relaxed.owl	pectin biosynthesis during cell wall organization and biogenesis|cell wall pectin biosynthesis													biological_process											owl:Class	
GO:0031228	biolink:NamedThing	intrinsic component of Golgi membrane	The component of the Golgi membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.	tmpzr1t_l9r_go_relaxed.owl	intrinsic to Golgi membrane													cellular_component											owl:Class	
GO:0008736	biolink:NamedThing	L-fucose isomerase activity	Catalysis of the reaction: L-fucose = L-fuculose.	tmpzr1t_l9r_go_relaxed.owl	L-fucose ketol-isomerase activity|L-fucose aldose-ketose-isomerase activity				RHEA:17233|EC:5.3.1.25|MetaCyc:FUCISOM-RXN									molecular_function											owl:Class	
GO:0046558	biolink:NamedThing	arabinan endo-1,5-alpha-L-arabinosidase activity	Catalysis of the endohydrolysis of (1->5)-alpha-arabinofuranosidic linkages in (1->5) arabinans.	tmpzr1t_l9r_go_relaxed.owl	endo-1,5-alpha-L-arabinanase activity|endo-alpha-1,5-arabanase activity|endo-arabanase activity|1,5-alpha-L-arabinan 1,5-alpha-L-arabinanohydrolase activity				EC:3.2.1.99|MetaCyc:3.2.1.99-RXN									molecular_function											owl:Class	
GO:0008904	biolink:NamedThing	hygromycin-B 7''-O-phosphotransferase activity	Catalysis of the reaction: ATP + hygromycin B = 7''-O-phosphohygromycin B + ADP + 2 H(+).	tmpzr1t_l9r_go_relaxed.owl	hygromycin-B kinase activity|destomic acid ring 7''-O-phosphotransferase activity|hygromycin B phosphotransferase activity|ATP:hygromycin-B 7''-O-phosphotransferase activity|APH(7'') activity|hygromycin B kinase activity				KEGG_REACTION:R03770|MetaCyc:HYGROMYCIN-B-KINASE-RXN|RHEA:23388|EC:2.7.1.119									molecular_function											owl:Class	
GO:1902049	biolink:NamedThing	neosartoricin catabolic process	The chemical reactions and pathways resulting in the breakdown of neosartoricin.	tmpzr1t_l9r_go_relaxed.owl	neosartoricin catabolism|neosartoricin breakdown|neosartoricin degradation							di	2013-04-08T20:31:06Z					biological_process											owl:Class	
GO:0120068	biolink:NamedThing	regulation of stomach fundus smooth muscle contraction	Any process that modulates the frequency, rate or extent of any stomach fundus smooth muscle contraction.	tmpzr1t_l9r_go_relaxed.owl								krc	2017-06-13T23:22:52Z					biological_process											owl:Class	
GO:0030580	biolink:NamedThing	quinone cofactor methyltransferase activity	Catalysis of the transfer of a methyl group from S-adenosylmethionine during the synthesis of quinone cofactors such as ubiquinone (coenzyme Q), menaquinone (vitamin K2), plastoquinone and phylloquinone (vitamin K1).	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1904397	biolink:NamedThing	negative regulation of neuromuscular junction development	Any process that stops, prevents or reduces the frequency, rate or extent of neuromuscular junction development.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of neuromuscular junction organization|down-regulation of neuromuscular junction organization|negative regulation of NMJ stability|down-regulation of NMJ stability|down regulation of neuromuscular junction stability|inhibition of neuromuscular junction stability|inhibition of neuromuscular junction development|inhibition of NMJ stability|downregulation of neuromuscular junction development|downregulation of neuromuscular junction organization|down-regulation of neuromuscular junction development|down-regulation of neuromuscular junction stability|inhibition of neuromuscular junction organization|down regulation of NMJ stability|down regulation of neuromuscular junction organization|negative regulation of neuromuscular junction stability|downregulation of NMJ stability|down regulation of neuromuscular junction development|downregulation of neuromuscular junction stability							sl	2015-06-23T19:23:48Z					biological_process											owl:Class	
GO:0030941	biolink:NamedThing	chloroplast targeting sequence binding	Binding to a chloroplast targeting sequence, a specific peptide sequence that acts as a signal to localize the protein within the chloroplast.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1904462	biolink:NamedThing	ergosteryl 3-beta-D-glucoside catabolic process	The chemical reactions and pathways resulting in the breakdown of ergosteryl 3-beta-D-glucoside.	tmpzr1t_l9r_go_relaxed.owl	ergosteryl 3-beta-D-glucoside breakdown|ergosteryl 3-beta-D-glucoside degradation|ergosteryl 3-beta-D-glucoside catabolism							mcc	2015-07-09T19:36:25Z					biological_process											owl:Class	
GO:0010785	biolink:NamedThing	clathrin coating of Golgi vesicle, plasma membrane to endosome targeting	The addition of clathrin and adaptor proteins to Golgi membranes during the formation of transport vesicles that will move from the plasma membrane to the endosome, forming a vesicle coat.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0014717	biolink:NamedThing	regulation of satellite cell activation involved in skeletal muscle regeneration	Any process that modulates the frequency, rate or extent of satellite cell activation. The satellite cell activation is the process that initiates satellite cell division by causing it to move from quiescence to the G1 stage of the cell cycle. The cell swells and there are a number of other small changes. The cells then start to divide. Following cell division the cells will differentiate.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1904796	biolink:NamedThing	regulation of core promoter binding	Any process that modulates the frequency, rate or extent of core promoter binding.	tmpzr1t_l9r_go_relaxed.owl								nc	2015-11-09T12:32:23Z					biological_process											owl:Class	
GO:0034667	biolink:NamedThing	integrin alpha3-beta1 complex	An integrin complex that comprises one alpha3 subunit and one beta1 subunit.	tmpzr1t_l9r_go_relaxed.owl	alpha3-beta1 integrin complex|VLA-3 complex|ITGA3-ITGB1 complex													cellular_component											owl:Class	
GO:1904934	biolink:NamedThing	negative regulation of cell proliferation in midbrain	Any process that stops, prevents or reduces the frequency, rate or extent of cell proliferation in midbrain.	tmpzr1t_l9r_go_relaxed.owl	downregulation of mesencepahalic cell proliferation|negative regulation of mesencepahalic cell proliferation|down regulation of cell proliferation in mesencephalon|downregulation of cell proliferation in midbrain|inhibition of mesencepahalic cell proliferation|negative regulation of cell proliferation in mesencephalon|down-regulation of cell proliferation in mesencephalon|downregulation of cell proliferation in mesencephalon|down-regulation of cell proliferation in midbrain|inhibition of cell proliferation in mesencephalon|down-regulation of mesencepahalic cell proliferation|inhibition of cell proliferation in midbrain|down regulation of cell proliferation in midbrain|down regulation of mesencepahalic cell proliferation							bf	2016-02-01T13:16:19Z					biological_process											owl:Class	
GO:0042796	biolink:NamedThing	snRNA transcription by RNA polymerase III	The synthesis of small nuclear RNA (snRNA) from a DNA template by RNA Polymerase III (Pol III), originating at a Pol III promoter.	tmpzr1t_l9r_go_relaxed.owl	snRNA transcription from Pol III promoter|snRNA transcription from RNA polymerase III promoter	https://github.com/geneontology/go-ontology/issues/14854												biological_process											owl:Class	
GO:0043682	biolink:NamedThing	P-type divalent copper transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Cu2+(in) -> ADP + phosphate + Cu2+(out).	tmpzr1t_l9r_go_relaxed.owl	copper exporting ATPase activity|Cu2+-exporting ATPase activity|copper-translocating P-type ATPase activity|copper transmembrane transporter activity, phosphorylative mechanism|Cu(2+)-exporting ATPase activity|copper-exporting ATPase activity|copper-transporting ATPase activity				EC:7.2.2.9|Reactome:R-HSA-6803545|Reactome:R-HSA-3697838|Reactome:R-HSA-936895|Reactome:R-HSA-936802|RHEA:10376|MetaCyc:3.6.3.4-RXN							GO:0004008		molecular_function											owl:Class	
GO:0034938	biolink:NamedThing	pyrrole-2-carboxylate monooxygenase activity	Catalysis of the reaction: pryrole-2-carboxylate + NADH + O2 + H+ = 5-hydroxypyrrole-2-carboxylate + NAD+ + H2O.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0968|EC:1.14.14.-									molecular_function											owl:Class	
GO:0046219	biolink:NamedThing	indolalkylamine biosynthetic process	The chemical reactions and pathways resulting in the formation of indolalkylamines, indole or indole derivatives containing a primary, secondary, or tertiary amine group.	tmpzr1t_l9r_go_relaxed.owl	indolalkylamine synthesis|indolalkylamine biosynthesis|indolalkylamine anabolism|indolalkylamine formation													biological_process											owl:Class	
GO:0019820	biolink:NamedThing	P2 peroxisome	A subform of peroxisome that corresponds to an intermediate in a peroxisome assembly pathway, which operates by conversion of peroxisomal subforms in the direction P1, P2 -> P3 -> P4 -> P5 -> P6. P2 peroxisomes are distinguished from the other subforms on the bases of buoyant density and protein content; they are the least dense of the subforms observed.	tmpzr1t_l9r_go_relaxed.owl	peroxisome vesicle					Note that this peroxisome assembly pathway is described in the yeast Yarrowia lipolytica. See also the cellular component terms 'P1 peroxisome ; GO:0019819', 'P3 peroxisome ; GO:0019821', 'P4 peroxisome ; GO:0019822', 'P5 peroxisome ; GO:0019823', and 'P6 peroxisome ; GO:0019824'.								cellular_component											owl:Class	
GO:1901819	biolink:NamedThing	alpha-zeacarotene metabolic process	The chemical reactions and pathways involving alpha-zeacarotene.	tmpzr1t_l9r_go_relaxed.owl	alpha-zeacarotene metabolism							yaf	2013-01-22T10:51:02Z					biological_process											owl:Class	
GO:1900730	biolink:NamedThing	negative regulation of adenylate cyclase-inhibiting opioid receptor signaling pathway	Any process that stops, prevents or reduces the frequency, rate or extent of adenylate cyclase-inhibiting opioid receptor signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	down regulation of adenylate cyclase-inhibiting opioid receptor signaling pathway|down-regulation of adenylate cyclase-inhibiting opioid receptor signaling pathway|downregulation of adenylate cyclase-inhibiting opioid receptor signaling pathway|inhibition of adenylate cyclase-inhibiting opioid receptor signaling pathway|negative regulation of inhibition of adenylate cyclase activity by opioid receptor signalling pathway|inhibition of opioid receptor-mediated adenylate cyclase inhibition|negative regulation of inhibition of adenylate cyclase activity by opioid receptor signaling pathway							bf	2012-05-25T03:21:12Z					biological_process											owl:Class	
GO:2000475	biolink:NamedThing	negative regulation of opioid receptor signaling pathway	Any process that stops, prevents or reduces the frequency, rate or extent of opioid receptor signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of opioid receptor signalling pathway							bf	2011-03-09T09:41:03Z					biological_process											owl:Class	
GO:0045294	biolink:NamedThing	alpha-catenin binding	Binding to catenin complex alpha subunit.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0047885	biolink:NamedThing	farnesol 2-isomerase activity	Catalysis of the reaction: 2-trans,6-trans-farnesol = 2-cis,6-trans-farnesol.	tmpzr1t_l9r_go_relaxed.owl	farnesol isomerase activity|2-trans,6-trans-farnesol 2-cis-trans-isomerase activity				MetaCyc:FARNESOL-2-ISOMERASE-RXN|EC:5.2.1.9|RHEA:13401|KEGG_REACTION:R03265									molecular_function											owl:Class	
GO:0051040	biolink:NamedThing	regulation of calcium-independent cell-cell adhesion	Any process that modulates the frequency, rate or extent of the attachment of one cell to another cell via adhesion molecules that do not require the presence of calcium for the interaction.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0044666	biolink:NamedThing	MLL3/4 complex	A protein complex that can methylate lysine-4 of histone H3, and which contains either of the protein subunits MLL3 or MLL4 in mammals, or equivalent in other species.	tmpzr1t_l9r_go_relaxed.owl	Trr/COMPASS-like complex							jl	2012-08-07T14:46:40Z					cellular_component											owl:Class	
GO:0048353	biolink:NamedThing	primary endosperm nucleus	Nucleus resulting from the fusion of the male gamete and two polar nuclei in the central cell of the embryo sac.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0072334	biolink:NamedThing	UDP-galactose transmembrane transport	The process in which UDP-galactose is transported across a membrane.	tmpzr1t_l9r_go_relaxed.owl	UDP-galactose membrane transport|UDP-galactose transport					Note that this term is not intended for use in annotating lateral movement within membranes.		mah	2010-11-03T02:03:36Z			GO:0015785		biological_process											owl:Class	
GO:0043827	biolink:NamedThing	tRNA (adenine-57, 58-N(1)-) methyltransferase activity	Catalysis of the methylation of adenine-57 and adenine-58 in the T-loop of tRNA.	tmpzr1t_l9r_go_relaxed.owl	TrmI|tRNA (adenine-57, 58-N1-) methyltransferase activity|tRNA (adenine-57, 58 N1-) methyltransferase activity|tRNA (m1A) MTase													molecular_function											owl:Class	
GO:0016429	biolink:NamedThing	tRNA (adenine-N1-)-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing N1-methyladenine.	tmpzr1t_l9r_go_relaxed.owl	adenine-1-methylase activity|S-adenosyl-L-methionine:tRNA (adenine-1-N-)-methyltransferase activity|1-methyladenine transfer RNA methyltransferase activity|transfer ribonucleate adenine 1-methyltransferase activity|transfer RNA (adenine-1) methyltransferase activity|S-adenosyl-L-methionine:tRNA (adenine-N1-)-methyltransferase activity				Reactome:R-HSA-6787594|Reactome:R-HSA-6787525|Reactome:R-HSA-6783492									molecular_function											owl:Class	
GO:0061848	biolink:NamedThing	cellular response to cholecystokinin	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cholecystokinin stimulus.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0008444	biolink:NamedThing	CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity	Catalysis of the reaction: sn-glycerol 3-phosphate + CDP-diacylglycerol = 3-(3-sn-phosphatidyl)-sn-glycerol 1-phosphate + CMP + H(+).	tmpzr1t_l9r_go_relaxed.owl	3-phosphatidyl-1'-glycerol-3'-phosphate synthase activity|phosphatidylglycerophosphate synthase activity|glycerol phosphate phosphatidyltransferase activity|phosphatidylglycerolphosphate synthase activity|PGP synthase activity|phosphatidylglycerol phosphate synthase activity|glycerophosphate phosphatidyltransferase activity|CDPdiacylglycerol:glycerol-3-phosphate phosphatidyltransferase activity|CDPdiacylglycerol-sn-glycerol-3-phosphate 3-phosphatidyltransferase activity|phosphatidylglycerol phosphate synthetase activity|CDP-diacylglycerol:sn-glycerol-3-phosphate 3-phosphatidyltransferase activity|CDPdiacylglycerol:sn-glycero-3-phosphate phosphatidyltransferase activity|sn-glycerol-3-phosphate phosphatidyltransferase activity|phosphatidylglycerophosphate synthetase activity|CDPdiacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity|cytidine 5'-diphospho-1,2-diacyl-sn-glycerol (CDPdiglyceride):sn-glycerol-3-phosphate phosphatidyltransferase activity|glycerol 3-phosphate phosphatidyltransferase activity				EC:2.7.8.5|KEGG_REACTION:R01801|Reactome:R-HSA-1482939|RHEA:12593|MetaCyc:PHOSPHAGLYPSYN-RXN									molecular_function											owl:Class	
GO:0050270	biolink:NamedThing	S-adenosylhomocysteine deaminase activity	Catalysis of the reaction: S-adenosyl-L-homocysteine + H(2)O + H(+) = S-inosyl-L-homocysteine + NH(4)(+).	tmpzr1t_l9r_go_relaxed.owl	adenosylhomocysteine deaminase activity|S-adenosyl-L-homocysteine aminohydrolase activity				KEGG_REACTION:R00193|EC:3.5.4.28|MetaCyc:S-ADENOSYLHOMOCYSTEINE-DEAMINASE-RXN|RHEA:20716									molecular_function											owl:Class	
GO:0032466	biolink:NamedThing	negative regulation of cytokinesis	Any process that stops, prevents, or reduces the frequency, rate or extent of the division of the cytoplasm of a cell, and its separation into two daughter cells.	tmpzr1t_l9r_go_relaxed.owl	downregulation of cytokinesis|negative regulation of cell cycle cytokinesis|down regulation of cytokinesis|inhibition of cytokinesis|down-regulation of cytokinesis											GO:0071776		biological_process											owl:Class	
GO:1900276	biolink:NamedThing	regulation of proteinase activated receptor activity	Any process that modulates the frequency, rate or extent of proteinase activated receptor activity.	tmpzr1t_l9r_go_relaxed.owl								rl	2012-04-04T01:31:20Z					biological_process											owl:Class	
GO:0046842	biolink:NamedThing	trisporic acid biosynthetic process	The chemical reactions and pathways resulting in the formation of trisporic acid.	tmpzr1t_l9r_go_relaxed.owl	trisporic acid anabolism|trisporic acid synthesis|trisporic acid biosynthesis|trisporic acid formation													biological_process											owl:Class	
GO:0046841	biolink:NamedThing	trisporic acid metabolic process	The chemical reactions and pathways involving trisporic acid, a carotenoic acid derivative used as a pheromone in some species of Zygomycota.	tmpzr1t_l9r_go_relaxed.owl	trisporic acid metabolism													biological_process											owl:Class	
GO:0030922	biolink:NamedThing	peptidyl-tyrosine dehydrogenation to form (E)-2,3-didehydrotyrosine	The oxidation of the C alpha-C beta bond of peptidyl-tyrosine to form peptidyl-(E)-2,3-didehydrotyrosine coupled with cyclization of neighboring residues.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0365									biological_process											owl:Class	
GO:0007430	biolink:NamedThing	terminal branching, open tracheal system	Formation of terminal branches in the open tracheal system. These are long cytoplasmic extensions that form fine tubules that transport oxygen directly to the tissues. An example of the process is found in Drosophila melanogaster.	tmpzr1t_l9r_go_relaxed.owl	terminal branching of trachea, cytoplasmic projection extension													biological_process											owl:Class	
GO:0080003	biolink:NamedThing	thalianol metabolic process	The chemical reactions and pathways involving the triterpene thalianol.	tmpzr1t_l9r_go_relaxed.owl	thalianol metabolism													biological_process											owl:Class	
GO:1990134	biolink:NamedThing	epithelial cell apoptotic process involved in palatal shelf morphogenesis	An apoptotic process in a palatal shelf epithelial cell that contributes to the shaping of the palatal shelf.	tmpzr1t_l9r_go_relaxed.owl								dph	2013-06-26T11:56:00Z					biological_process											owl:Class	
GO:0044363	biolink:NamedThing	modulation of potassium channel activity in other organism	Any process in which an organism effects a change in the frequency, rate or extent of the activity of a potassium channel in another organism.	tmpzr1t_l9r_go_relaxed.owl								jl	2011-10-27T02:19:32Z					biological_process											owl:Class	
GO:0051075	biolink:NamedThing	S-adenosylmethionine:tRNA ribosyltransferase-isomerase activity	Catalysis of the reaction: S-adenosylmethionine + 7-(aminomethyl)-7-deazaguanosine-tRNA = adenine + methionine + epoxyqueuosine-tRNA. 7-(aminomethyl)-7-deazaguanosine-tRNA is also known as preQ1-tRNA, and epoxyqueuosine-tRNA as oQ-tRNA.	tmpzr1t_l9r_go_relaxed.owl	S-adenosyl methionine:tRNA ribosyltransferase-isomerase activity				EC:2.4.99.17|RHEA:32155									molecular_function											owl:Class	
GO:0140618	biolink:NamedThing	ferric-chelate reductase (NADH) activity	Catalysis of the reaction:  2 Fe3+-siderophore + NAD(+) + H(+) -> 2 Fe2+-siderophore + NADH.	tmpzr1t_l9r_go_relaxed.owl	NADH:Fe3+ oxidoreductase activity|ferric chelate reductase activity|iron chelate reductase activity|NADH:Fe(3+) oxidoreductase activity	https://github.com/geneontology/go-ontology/issues/21029			MetaCyc:FERRIC-CHELATE-REDUCTASE-RXN|RHEA:15061|EC:1.16.1.7			pg	2021-03-09T07:20:30Z					molecular_function											owl:Class	
GO:0047694	biolink:NamedThing	barbiturase activity	Catalysis of the reaction: barbiturate + H2O = malonate + urea.	tmpzr1t_l9r_go_relaxed.owl	barbiturate amidohydrolase (3-oxo-3-ureidopropanoate-forming)				RHEA:18653|MetaCyc:BARBITURASE-RXN|EC:3.5.2.1									molecular_function											owl:Class	
GO:0140217	biolink:NamedThing	positive regulation of D-aspartate import across plasma membrane	Any process that activates or increases the frequency, rate or extent of the directed import of D-aspartate from the extracellular region across the plasma membrane and into the cytosol.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/15041						pg	2018-04-11T15:45:22Z					biological_process											owl:Class	
GO:0075316	biolink:NamedThing	negative regulation of basidium development	Any process that stops, prevents, or reduces the frequency, rate or extent of basidium development, a process that leads to the formation of basidium, a small, specialized club-shaped structure typically bearing four basidiospores at the tips of minute projections. The basidium is unique to basidiomycetes and distinguishes them from other kinds of fungi.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0047903	biolink:NamedThing	fructose 5-dehydrogenase (NADP+) activity	Catalysis of the reaction: D-fructose + NADP+ = 5-dehydro-D-fructose + NADPH.	tmpzr1t_l9r_go_relaxed.owl	5-ketofructose reductase (NADP(+)) activity|fructose 5-(nicotinamide adenine dinucleotide phosphate) dehydrogenase activity|D-fructose:NADP+ 5-oxidoreductase activity|5-ketofructose reductase (NADP)|5-keto-D-fructose reductase (NADP+)|D-(-)fructose:(NADP+) 5-oxidoreductase activity|5-ketofructose reductase (NADP+) activity				RHEA:14069|EC:1.1.1.124|MetaCyc:FRUCTOSE-5-DEHYDROGENASE-NADP+-RXN									molecular_function											owl:Class	
GO:0034014	biolink:NamedThing	response to triglyceride	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a triglyceride stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to triacylglycerol|response to triacylglyceride													biological_process											owl:Class	
GO:0099538	biolink:NamedThing	synaptic signaling via neuropeptide	Cell-cell signaling to or from a synapse, mediated by a peptide.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0006194	biolink:NamedThing	dIDP phosphorylation	The process of introducing a phosphate group into dIDP, deoxyinosine diphosphate, to produce dITP.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1990229	biolink:NamedThing	iron-sulfur cluster assembly complex	A protein complex capable of assembling an iron-sulfur (Fe-S) cluster.	tmpzr1t_l9r_go_relaxed.owl	SufBCD complex|Fe-S cluster assembly complex							bhm	2013-11-12T09:15:03Z					cellular_component											owl:Class	
GO:0018146	biolink:NamedThing	keratan sulfate biosynthetic process	The chemical reactions and pathways resulting in the formation of keratan sulfate, a glycosaminoglycan with repeat units consisting of beta-1,4-linked D-galactopyranosyl-beta-(1,4)-N-acetyl-D-glucosamine 6-sulfate and with variable amounts of fucose, sialic acid and mannose units; keratan sulfate chains are covalently linked by a glycosidic attachment through the trisaccharide galactosyl-galactosyl-xylose to peptidyl-threonine or serine residues.	tmpzr1t_l9r_go_relaxed.owl	keratan sulphate biosynthesis|keratan sulfate anabolism|keratan sulfate formation|keratan sulfate biosynthesis|keratan sulphate biosynthetic process|keratan sulfate synthesis				RESID:AA0247									biological_process											owl:Class	
GO:0030713	biolink:NamedThing	ovarian follicle cell stalk formation	Development of ovarian follicle cells to create the interfollicular stalks that connect the egg chambers of progressive developmental stages. An example of this process is found in Drosophila melanogaster.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0010305	biolink:NamedThing	leaf vascular tissue pattern formation	Vascular tissue pattern formation as it occurs in the leaf of vascular plants.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0045652	biolink:NamedThing	regulation of megakaryocyte differentiation	Any process that modulates the frequency, rate or extent of megakaryocyte differentiation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0031505	biolink:NamedThing	fungal-type cell wall organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the fungal-type cell wall.	tmpzr1t_l9r_go_relaxed.owl	chitin- and beta-glucan-containing cell wall organisation|fungal-type cell wall organization and biogenesis|chitin-containing cell wall organization and biogenesis|chitin- and beta-glucan-containing cell wall organization and biogenesis|beta-glucan-containing cell wall organization and biogenesis													biological_process											owl:Class	
GO:0071852	biolink:NamedThing	fungal-type cell wall organization or biogenesis	A process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a fungal-type cell wall.	tmpzr1t_l9r_go_relaxed.owl	fungal-type cell wall organization and biogenesis|fungal-type cell wall organisation or biogenesis							mah	2010-09-10T03:07:55Z					biological_process											owl:Class	
GO:0050302	biolink:NamedThing	indole-3-acetaldehyde oxidase activity	Catalysis of the reaction: (indol-3-yl)acetaldehyde + H(2)O + O(2) = (indol-3-yl)acetate + H(2)O(2) + H(+).	tmpzr1t_l9r_go_relaxed.owl	AO1|(indol-3-yl)acetaldehyde:oxygen oxidoreductase activity|IAA oxidase activity|indole-3-acetaldehyde:oxygen oxidoreductase activity|indoleacetaldehyde oxidase activity|IAAld oxidase activity				MetaCyc:INDOLE-3-ACETALDEHYDE-OXIDASE-RXN|EC:1.2.3.7|RHEA:16277|KEGG_REACTION:R02681									molecular_function											owl:Class	
GO:1901050	biolink:NamedThing	atropine catabolic process	The chemical reactions and pathways resulting in the breakdown of atropine.	tmpzr1t_l9r_go_relaxed.owl	atropine catabolism|atropine breakdown|atropine degradation							yaf	2012-06-28T04:51:51Z					biological_process											owl:Class	
GO:0002773	biolink:NamedThing	B cell inhibitory signaling pathway	A series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of a B cell capable of inhibiting an immune effector process contributing to an immune response.	tmpzr1t_l9r_go_relaxed.owl	B-cell inhibitory signaling pathway|B cell inhibitory signalling pathway|B lymphocyte inhibitory signaling pathwayBT-lymphocyte inhibitory signaling pathway													biological_process											owl:Class	
GO:0106157	biolink:NamedThing	peptidyl-arginine 3-dioxygenase activity	Catalyzes the reaction: 2-oxoglutarate + [protein]-L-arginine + O2 = [protein]-(3R)-3-hydroxy-L-arginine + CO2 + succinate.	tmpzr1t_l9r_go_relaxed.owl	L-arginine 3-hydroxylase activity	https://github.com/geneontology/go-ontology/issues/16689			RHEA:56744			hjd	2018-11-26T15:05:57Z			GO:0140554		molecular_function											owl:Class	
GO:2000527	biolink:NamedThing	regulation of myeloid dendritic cell chemotaxis	Any process that modulates the frequency, rate or extent of myeloid dendritic cell chemotaxis.	tmpzr1t_l9r_go_relaxed.owl								ebc	2011-03-23T12:18:32Z					biological_process											owl:Class	
GO:0019436	biolink:NamedThing	sophorosyloxydocosanoate catabolic process	The chemical reactions and pathways resulting in the breakdown of sophorosyloxydocosanoate, 13-sophorosyloxydocosanoate 6',6''-diacetate.	tmpzr1t_l9r_go_relaxed.owl	sophorosyloxydocosanoate catabolism|sophorosyloxydocosanoate degradation|sophorosyloxydocosanoate breakdown				MetaCyc:SOPHOROSYLOXYDOCOSANOATE-DEG-PWY									biological_process											owl:Class	
GO:0033580	biolink:NamedThing	protein galactosylation at cell surface	The addition of a galactose unit to a protein amino acid at the surface of a cell.	tmpzr1t_l9r_go_relaxed.owl	protein amino acid galactosylation at cell surface													biological_process											owl:Class	
GO:0034099	biolink:NamedThing	luminal surveillance complex	A multiprotein complex that recognizes ERAD-luminal misfolded substrates and brings them to the ubiquitination/extraction machinery. In yeast, this complex consists of Yos9p, Kar2p and Hrd3p proteins.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:1905166	biolink:NamedThing	negative regulation of lysosomal protein catabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of lysosomal protein catabolic process.	tmpzr1t_l9r_go_relaxed.owl	down regulation of lysosomal protein degradation|inhibition of lysosomal proteolysis|inhibition of lysosomal protein catabolic process|downregulation of cellular protein catabolic process in lysosome|down regulation of cellular protein catabolic process in lysosome|negative regulation of lysosomal protein degradation|downregulation of cellular protein degradation in lysosome|down regulation of proteolysis within lysosome|negative regulation of lysosomal protein catabolism|downregulation of proteolysis within lysosome|inhibition of cellular protein breakdown in lysosome|down regulation of lysosomal proteolysis|down regulation of cellular protein catabolism in lysosome|downregulation of lysosomal proteolysis|inhibition of cellular protein catabolic process in lysosome|down regulation of lysosomal protein catabolism|downregulation of lysosomal protein catabolic process|down-regulation of cellular protein breakdown in lysosome|negative regulation of cellular protein degradation in lysosome|down-regulation of lysosomal proteolysis|down regulation of cellular protein degradation in lysosome|negative regulation of proteolysis within lysosome|downregulation of cellular protein catabolism in lysosome|down-regulation of lysosomal protein catabolic process|inhibition of cellular protein catabolism in lysosome|downregulation of lysosomal protein degradation|downregulation of cellular protein breakdown in lysosome|downregulation of lysosomal protein catabolism|down-regulation of lysosomal protein degradation|negative regulation of cellular protein catabolic process in lysosome|down regulation of cellular protein breakdown in lysosome|negative regulation of cellular protein breakdown in lysosome|down-regulation of cellular protein catabolism in lysosome|negative regulation of lysosomal proteolysis|inhibition of cellular protein degradation in lysosome|down regulation of lysosomal protein catabolic process|inhibition of lysosomal protein catabolism|inhibition of lysosomal protein degradation|inhibition of proteolysis within lysosome|down-regulation of proteolysis within lysosome|down-regulation of cellular protein catabolic process in lysosome|negative regulation of cellular protein catabolism in lysosome|down-regulation of lysosomal protein catabolism|down-regulation of cellular protein degradation in lysosome							bf	2016-04-26T12:10:10Z					biological_process											owl:Class	
GO:0047221	biolink:NamedThing	sn-glycerol-3-phosphate 2-alpha-galactosyltransferase activity	Catalysis of the reaction: sn-glycerol 3-phosphate + UDP-D-galactose = 2-(alpha-D-galactosyl)-sn-glycerol 3-phosphate + H(+) + UDP.	tmpzr1t_l9r_go_relaxed.owl	floridoside phosphate synthetase activity|floridoside-phosphate synthase activity|floridoside phosphate synthase activity|UDP-galactose:sn-glycerol-3-phosphate 2-alpha-D-galactosyltransferase activity|UDP-galactose, sn-3-glycerol phosphate:1->2' galactosyltransferase activity|UDP-galactose:sn-glycerol-3-phosphate-2-D-galactosyl transferase activity|FPS|UDPgalactose:sn-glycerol-3-phosphate 2-alpha-D-galactosyltransferase activity				EC:2.4.1.137|RHEA:14285|KEGG_REACTION:R00853|MetaCyc:2.4.1.137-RXN									molecular_function											owl:Class	
GO:0043636	biolink:NamedThing	bisphenol A catabolic process	The chemical reactions and pathways resulting in the breakdown of bisphenol A, 4,4'-(propane-2,2-diyl)diphenol, a synthetic, aromatic organic compound used as a monomer in the manufacture of polycarbonate plastic and in the manufacture of epoxy resins.	tmpzr1t_l9r_go_relaxed.owl	bisphenol-A catabolism|bisphenol-A catabolic process													biological_process											owl:Class	
GO:0031511	biolink:NamedThing	Mis6-Sim4 complex	A protein complex that forms part of the inner kinetochore, which is involved in the loading of the centromeric histone h3 variant CENP-A onto centromeres and in centromere specific heterochromatin formation. The complex contains about 12 proteins, of which two are known as Mis6 and Sim4 in S. pombe and CENP-I and CENP-H in human.	tmpzr1t_l9r_go_relaxed.owl	Mis6 centromere subcomplex|Mis6-Mal2-Sim4 centromere complex|Sim4 complex													cellular_component											owl:Class	
GO:0033777	biolink:NamedThing	lithocholate 6beta-hydroxylase activity	Catalysis of the reaction: H(+) + lithocholate + NADPH + O(2) = 6-beta-hydroxylithocholate + H(2)O + NADP(+).	tmpzr1t_l9r_go_relaxed.owl	lithocholate,NADPH:oxygen oxidoreductase (6beta-hydroxylating) activity|6beta-hydroxylase activity|cytochrome P450 3A10/lithocholic acid 6beta-hydroxylase activity|CYP3A10|lithocholate 6beta-monooxygenase activity				EC:1.14.14.138|MetaCyc:1.14.13.94-RXN|KEGG_REACTION:R07203|RHEA:18857									molecular_function											owl:Class	
GO:1900991	biolink:NamedThing	scopolamine biosynthetic process	The chemical reactions and pathways resulting in the formation of scopolamine.	tmpzr1t_l9r_go_relaxed.owl	scopolamine formation|scopolamine synthesis|scopolamine anabolism|scopolamine biosynthesis							yaf	2012-06-14T09:48:07Z					biological_process											owl:Class	
GO:1900989	biolink:NamedThing	scopolamine metabolic process	The chemical reactions and pathways involving scopolamine.	tmpzr1t_l9r_go_relaxed.owl	scopolamine metabolism							yaf	2012-06-14T09:47:38Z					biological_process											owl:Class	
GO:0080057	biolink:NamedThing	sepal vascular tissue pattern formation	Vascular tissue pattern formation as it occurs in the sepal of vascular plants.	tmpzr1t_l9r_go_relaxed.owl								dhl	2009-04-13T02:26:19Z					biological_process											owl:Class	
GO:0061742	biolink:NamedThing	chaperone-mediated autophagy translocation complex	A lysosomal membrane protein complex that enables the translocation of a target protein across the lysosomal membrane as part of chaperone-mediated autophagy.	tmpzr1t_l9r_go_relaxed.owl	CMA translocation complex|CMA receptor complex|chaperone-mediated autophagy receptor complex	https://github.com/geneontology/go-ontology/issues/20850						dph	2015-10-23T07:39:04Z					cellular_component											owl:Class	
GO:0072106	biolink:NamedThing	regulation of ureteric bud formation	Any process that modulates the developmental process pertaining to the initial formation of the ureteric bud from the Wolffian duct.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-02-12T02:34:40Z					biological_process											owl:Class	
GO:0007057	biolink:NamedThing	spindle assembly involved in female meiosis I	The aggregation, arrangement and bonding together of a set of components to form the spindle during meiosis I of a meiotic cell cycle in females. An example of this is found in Drosophila melanogaster.	tmpzr1t_l9r_go_relaxed.owl	female meiosis I spindle assembly													biological_process											owl:Class	
GO:2000978	biolink:NamedThing	negative regulation of forebrain neuron differentiation	Any process that stops, prevents or reduces the frequency, rate or extent of forebrain neuron differentiation.	tmpzr1t_l9r_go_relaxed.owl								yaf	2011-08-03T12:09:16Z					biological_process											owl:Class	
GO:0061185	biolink:NamedThing	negative regulation of dermatome development	Any process that decreases the rate, frequency, or extent of the progression of the dermatome over time, from its initial formation to the mature structure. The dermatome is the portion of a somite that will form skin.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-07-14T08:43:08Z					biological_process											owl:Class	
GO:0047501	biolink:NamedThing	(+)-neomenthol dehydrogenase activity	Catalysis of the reaction: (+)-neomenthol + NADP(+) = (2S,5R)-menthone + H(+) + NADPH.	tmpzr1t_l9r_go_relaxed.owl	monoterpenoid dehydrogenase activity|(+)-neomenthol:NADP+ oxidoreductase activity				MetaCyc:+-NEOMENTHOL-DEHYDROGENASE-RXN|KEGG_REACTION:R02548|EC:1.1.1.208|RHEA:23812									molecular_function											owl:Class	
GO:0033754	biolink:NamedThing	indoleamine 2,3-dioxygenase activity	Catalysis of the reaction: tryptophan + O2 = N-formylkynurenine. The product of the reaction depends on the substrate; D-tryptophan produces N-formyl-D-kynurenine, and L-tryptophan produces N-formyl-L-kynurenine.	tmpzr1t_l9r_go_relaxed.owl	tryptophan pyrrolase activity|IDO|D-tryptophan:oxygen 2,3-oxidoreductase (decyclizing) activity				EC:1.13.11.52|RHEA:14189|MetaCyc:RXN-8665|MetaCyc:RXN-8664									molecular_function											owl:Class	
GO:0005316	biolink:NamedThing	high-affinity inorganic phosphate:sodium symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: HPO42-(out) + Na+(out) = HPO42-(in) + Na+(in). In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.	tmpzr1t_l9r_go_relaxed.owl	high affinity inorganic phosphate:sodium symporter activity|sodium/phosphate cotransporter activity													molecular_function											owl:Class	
GO:0018895	biolink:NamedThing	dibenzothiophene metabolic process	The chemical reactions and pathways involving dibenzothiophene, a substance composed of two benzene rings linked by one sulfide bond and one carbon-carbon bond. Dibenzothiophene derivatives can be detected in diesel oil following hydrodesulfurization treatment to remove sulfur compounds that would otherwise generate sulfur oxides during combustion.	tmpzr1t_l9r_go_relaxed.owl	diphenylene sulfide metabolic process|diphenylene sulfide metabolism|dibenzothiophene metabolism													biological_process											owl:Class	
GO:0032730	biolink:NamedThing	positive regulation of interleukin-1 alpha production	Any process that activates or increases the frequency, rate, or extent of interleukin-1 alpha production.	tmpzr1t_l9r_go_relaxed.owl	stimulation of interleukin-1 alpha production|up regulation of interleukin-1 alpha production|positive regulation of interleukin-1 alpha biosynthetic process|activation of interleukin-1 alpha production|positive regulation of IL-1 alpha production|up-regulation of interleukin-1 alpha production|positive regulation of interleukin-1 alpha secretion|upregulation of interleukin-1 alpha production											GO:0050717|GO:0050726		biological_process											owl:Class	
GO:0050152	biolink:NamedThing	omega-amidase activity	Catalysis of the reaction: a monoamide of a dicarboxylic acid + H2O = a dicarboxylate + NH3.	tmpzr1t_l9r_go_relaxed.owl	omega-amidodicarboxylate amidohydrolase activity|alpha-keto acid-omega-amidase activity|w-amidase activity				MetaCyc:OMEGA-AMIDASE-RXN|RHEA:11716|EC:3.5.1.3									molecular_function											owl:Class	
GO:0046001	biolink:NamedThing	negative regulation of preblastoderm mitotic cell cycle	Any process that stops, prevents or reduces the rate or extent of progression through the preblastoderm mitotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of preblastoderm mitotic cell cycle progression|inhibition of progression through preblastoderm mitotic cell cycle|downregulation of progression through preblastoderm mitotic cell cycle|down-regulation of progression through preblastoderm mitotic cell cycle|negative regulation of progression through preblastoderm mitotic cell cycle|down regulation of progression through preblastoderm mitotic cell cycle													biological_process											owl:Class	
GO:0010433	biolink:NamedThing	bract morphogenesis	The process in which the anatomical structure of a bract are generated and organized. A bract is a leaf, usually different in form from the foliage leaves, subtending a flower or inflorescence.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0097402	biolink:NamedThing	neuroblast migration	The orderly movement of a neuroblast from one site to another, often during the development of a multicellular organism or multicellular structure. A neuroblast is any cell that will divide and give rise to a neuron.	tmpzr1t_l9r_go_relaxed.owl								pr	2012-10-29T08:24:37Z					biological_process											owl:Class	
GO:0042955	biolink:NamedThing	dextrin transport	The directed movement of dextrin, any one, or the mixture, of the intermediate polysaccharides formed during the hydrolysis of starch, which are dextrorotatory, soluble in water, and precipitable in alcohol, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1902089	biolink:NamedThing	cell wall polysaccharide catabolic process involved in lateral root development	Any cell wall polysaccharide catabolic process that is involved in lateral root development.	tmpzr1t_l9r_go_relaxed.owl	cell wall polysaccharide breakdown involved in lateral root development							tb	2013-04-26T18:34:53Z					biological_process											owl:Class	
GO:0103082	biolink:NamedThing	2-(4'-methylthio)butylmalate synthase activity	Catalysis of the reaction: 2-oxo-6-methylthiohexanoate + acetyl-CoA + H2O <=> H+ + 2-(4'-methylthio)butylmalate + coenzyme A.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXNQT-4166									molecular_function											owl:Class	
GO:0004108	biolink:NamedThing	citrate (Si)-synthase activity	Catalysis of the reaction: acetyl-CoA + H2O + oxaloacetate = citrate + CoA, where the acetyl group is added to the si-face of oxaloacetate; acetyl-CoA thus provides the two carbon atoms of the pro-S carboxymethyl group.	tmpzr1t_l9r_go_relaxed.owl	condensing enzyme activity|citrate oxaloacetate-lyase ((pro-3S)-CH2COO-rightacetyl-CoA)|citrate oxaloacetate-lyase [(pro-3S)-CH2COOrightacetyl-CoA]|citric-condensing enzyme activity|citrate condensing enzyme activity|citrogenase activity|oxaloacetate transacetase activity|citrate oxaloacetate-lyase ((pro-3S)-CH(2)COO(-)->acetyl-CoA) activity|acetyl-CoA:oxaloacetate C-acetyltransferase [thioester-hydrolysing, (pro-S)-carboxymethyl forming]|citrate synthase activity|citric synthase activity|(R)-citric synthase activity|citrate synthetase activity|citrate oxaloacetate-lyase, CoA-acetylating activity|oxalacetic transacetase activity				EC:2.3.3.1|Reactome:R-HSA-70975|MetaCyc:CITSYN-RXN	Note that this function was formerly EC:4.1.3.7.								molecular_function											owl:Class	
GO:0016828	biolink:NamedThing	hydrolase activity, acting on acid sulfur-sulfur bonds	Catalysis of the hydrolysis of any acid sulfur-sulfur bond.	tmpzr1t_l9r_go_relaxed.owl	hydrolase activity, acting on acid sulphur-sulphur bonds				EC:3.12.-.-									molecular_function											owl:Class	
GO:1990787	biolink:NamedThing	negative regulation of hh target transcription factor activity	Any process that decreases the activity of a transcription factor that activates transcription of Hedgehog-target genes in response to Smoothened signaling. In Drosophila, Cubitus interruptus (Ci) is the only identified transcription factor so far in the Hedgehog signaling pathway. In vertebrates members of the Gli protein family are activated by Hedgehog signaling.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of hedgehog target transcription factor							bhm	2015-06-26T09:54:29Z					biological_process											owl:Class	
GO:0072714	biolink:NamedThing	response to selenite ion	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a selenite ion stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2012-04-19T02:46:28Z					biological_process											owl:Class	
GO:0014701	biolink:NamedThing	junctional sarcoplasmic reticulum membrane	The part of the sarcoplasmic reticulum membrane that contains calcium release channels, is devoted to calcium release and is juxtaposed to transverse tubule membrane. The junctional sarcoplasmic reticulum membrane consists of the junctional region of the terminal cisterna membrane.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0009202	biolink:NamedThing	deoxyribonucleoside triphosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of a deoxyribonucleoside triphosphate, a compound consisting of a nucleobase linked to a deoxyribose sugar esterified with triphosphate on the sugar.	tmpzr1t_l9r_go_relaxed.owl	deoxyribonucleoside triphosphate synthesis|deoxyribonucleoside triphosphate biosynthesis|deoxyribonucleoside triphosphate formation|deoxyribonucleoside triphosphate anabolism													biological_process											owl:Class	
GO:0009200	biolink:NamedThing	deoxyribonucleoside triphosphate metabolic process	The chemical reactions and pathways involving a deoxyribonucleoside triphosphate, a compound consisting of a nucleobase linked to a deoxyribose sugar esterified with triphosphate on the sugar.	tmpzr1t_l9r_go_relaxed.owl	deoxyribonucleoside triphosphate metabolism													biological_process											owl:Class	
GO:0018203	biolink:NamedThing	peptidyl-isoleucine modification	The modification of peptidyl-isoleucine.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0051192	biolink:NamedThing	prosthetic group binding	Binding to a prosthetic group, the non-amino acid portion of certain protein molecules. Prosthetic groups may be inorganic or organic and are usually required for the biological activity of the protein.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0032166	biolink:NamedThing	chlamydospore septin filament array	Arrays of septin filaments, or bars, found in a series of filamentous structures. Observed in the chlamydospore membrane during chlamydospore formation.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:1905210	biolink:NamedThing	regulation of fibroblast chemotaxis	Any process that modulates the frequency, rate or extent of fibroblast chemotaxis.	tmpzr1t_l9r_go_relaxed.owl								sl	2016-06-02T20:08:42Z					biological_process											owl:Class	
GO:0070317	biolink:NamedThing	negative regulation of G0 to G1 transition	A cell cycle process that stops, prevents, or reduces the rate or extent of the transition from the G0 quiescent state to the G1 phase.	tmpzr1t_l9r_go_relaxed.owl	maintenance of G0 phase|maintenance of cell cycle quiescence|maintenance of cell quiescence|maintenance of G0 arrest													biological_process											owl:Class	
GO:0102820	biolink:NamedThing	norbixin methyltransferase activity	Catalysis of the reaction: norbixin + S-adenosyl-L-methionine  <=> bixin + S-adenosyl-L-homocysteine.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-8238									molecular_function											owl:Class	
GO:1903123	biolink:NamedThing	regulation of thioredoxin peroxidase activity	Any process that modulates the frequency, rate or extent of thioredoxin peroxidase activity.	tmpzr1t_l9r_go_relaxed.owl	regulation of thiol peroxidase activity|regulation of TPx activity|regulation of TrxPx activity							bf	2014-06-18T11:03:11Z					biological_process											owl:Class	
GO:0061874	biolink:NamedThing	positive regulation of hepatic stellate cell contraction	Any process that activates or increases the frequency, rate or extent of hepatic stellate cell contraction.	tmpzr1t_l9r_go_relaxed.owl								dph	2017-05-01T13:29:30Z					biological_process											owl:Class	
GO:0090459	biolink:NamedThing	aspartate homeostasis	Any process involved in the maintenance of an internal steady state of aspartate within an organism or cell.	tmpzr1t_l9r_go_relaxed.owl								tb	2012-09-24T14:22:02Z					biological_process											owl:Class	
GO:0030952	biolink:NamedThing	establishment or maintenance of cytoskeleton polarity	Any cellular process that results in the specification, formation or maintenance of polarized cytoskeletal structures.	tmpzr1t_l9r_go_relaxed.owl	cytoskeleton polarization													biological_process											owl:Class	
GO:0004460	biolink:NamedThing	L-lactate dehydrogenase (cytochrome) activity	Catalysis of the reaction: (S)-lactate + 2 [Fe(III)cytochrome c] = 2 [Fe(II)cytochrome c] + 2 H+ + pyruvate.	tmpzr1t_l9r_go_relaxed.owl	flavocytochrome b2|cytochrome b2 (flavin-free derivative of flavocytochrome b2)|lactic cytochrome c reductase activity|(S)-lactate:ferricytochrome-c 2-oxidoreductase activity|L-lactate cytochrome c reductase activity|lactic acid dehydrogenase activity|dehydrogenase, lactate (cytochrome)|L-lactate cytochrome c oxidoreductase activity|cytochrome b2|lactate dehydrogenase (cytochrome)|L-lactate ferricytochrome c oxidoreductase activity|L(+)-lactate:cytochrome c oxidoreductase activity				MetaCyc:L-LACTATE-DEHYDROGENASE-CYTOCHROME-RXN|EC:1.1.2.3|RHEA:19909									molecular_function											owl:Class	
GO:0044078	biolink:NamedThing	positive regulation by symbiont of host receptor-mediated endocytosis	Any process in which a symbiont organism activates or increases the frequency, rate or extent of receptor mediated endocytosis, the uptake of external materials by cells, utilizing receptors to ensure specificity of transport, in its host organism.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of host receptor-mediated endocytosis by symbiont													biological_process											owl:Class	
GO:0044077	biolink:NamedThing	modulation by symbiont of host receptor-mediated endocytosis	The process in which a symbiont organism modulates the frequency, rate or extent of receptor mediated endocytosis, the uptake of external materials by cells, utilizing receptors to ensure specificity of transport, in its host organism.	tmpzr1t_l9r_go_relaxed.owl	modulation of host receptor-mediated endocytosis by symbiont|regulation by symbiont of host receptor-mediated endocytosis													biological_process											owl:Class	
GO:1900879	biolink:NamedThing	(Z)-nonadeca-1,14-diene biosynthetic process	The chemical reactions and pathways resulting in the formation of (Z)-nonadeca-1,14-diene.	tmpzr1t_l9r_go_relaxed.owl	(Z)-nonadeca-1,14-diene formation|(Z)-nonadeca-1,14-diene biosynthesis|(Z)-nonadeca-1,14-diene synthesis|(Z)-nonadeca-1,14-diene anabolism							tt	2012-06-13T02:09:39Z					biological_process											owl:Class	
GO:0080085	biolink:NamedThing	signal recognition particle, chloroplast targeting	A complex consisting of a protein and RNA component which binds the signal sequence of some proteins and facilitates their export to the chloroplast.	tmpzr1t_l9r_go_relaxed.owl								dhl	2009-04-22T02:36:01Z					cellular_component											owl:Class	
GO:1900223	biolink:NamedThing	positive regulation of amyloid-beta clearance	Any process that activates or increases the frequency, rate or extent of amyloid-beta clearance.	tmpzr1t_l9r_go_relaxed.owl	up regulation of beta-amyloid clearance|activation of beta-amyloid clearance|up-regulation of beta-amyloid clearance|upregulation of beta-amyloid clearance|positive regulation of beta-amyloid clearance							vk	2012-03-22T01:29:50Z					biological_process											owl:Class	
GO:1903950	biolink:NamedThing	negative regulation of AV node cell action potential	Any process that stops, prevents or reduces the frequency, rate or extent of AV node cell action potential.	tmpzr1t_l9r_go_relaxed.owl	down regulation of AV node cardiac muscle cell action potential|negative regulation of AV node cardiac muscle cell action potential|negative regulation of atrioventricular node cardiac muscle cell action potential|downregulation of atrioventricular node cardiac muscle cell action potential|down regulation of atrioventricular node cardiac muscle cell action potential|downregulation of AV node cell action potential|inhibition of AV node cell action potential|down regulation of AV node cell action potential|down-regulation of atrioventricular node cardiac muscle cell action potential|down-regulation of AV node cardiac muscle cell action potential|inhibition of atrioventricular node cardiac muscle cell action potential|down-regulation of AV node cell action potential|inhibition of AV node cardiac muscle cell action potential|downregulation of AV node cardiac muscle cell action potential							nc	2015-02-20T14:59:41Z					biological_process											owl:Class	
GO:0044224	biolink:NamedThing	juxtaparanode region of axon	A region of an axon near a node of Ranvier that is between the paranode and internode regions.	tmpzr1t_l9r_go_relaxed.owl	juxtaparanode|juxtaparanodal region|juxta paranode axon				NIF_Subcellular:sao758620702			jl	2009-11-13T12:57:36Z					cellular_component											owl:Class	
GO:0008401	biolink:NamedThing	retinoic acid 4-hydroxylase activity	Catalysis of the conversion of retinoic acid to 4-hydroxy-retinoic acid.	tmpzr1t_l9r_go_relaxed.owl	cytochrome P450 CYP261				Reactome:R-HSA-211874|Reactome:R-HSA-212007|Reactome:R-HSA-211923|Reactome:R-HSA-5602063|Reactome:R-HSA-5602050|Reactome:R-HSA-5362525									molecular_function											owl:Class	
GO:0018903	biolink:NamedThing	1,3-dichloropropene metabolic process	The chemical reactions and pathways involving members of the 1,3-dichloropropene family, which includes cis- and trans-1,3-dichloropropene. The 1,3-dichloropropenes are chlorinated hydrocarbons and the major active ingredients of commercial products for control of plant-parasitic nematodes.	tmpzr1t_l9r_go_relaxed.owl	gamma-chloroallylchloride metabolic process|gamma-chloroallylchloride metabolism|1,3-dichloropropene metabolism|1,3-dichloropropylene metabolic process|1,3-dichloropropylene metabolism				UM-BBD_pathwayID:cpr									biological_process											owl:Class	
GO:0046628	biolink:NamedThing	positive regulation of insulin receptor signaling pathway	Any process that increases the frequency, rate or extent of insulin receptor signaling.	tmpzr1t_l9r_go_relaxed.owl	upregulation of insulin receptor signaling pathway|up-regulation of insulin receptor signaling pathway|activation of insulin receptor signaling pathway|positive regulation of insulin receptor signalling pathway|up regulation of insulin receptor signaling pathway|stimulation of insulin receptor signaling pathway													biological_process											owl:Class	
GO:0047148	biolink:NamedThing	methylamine-glutamate N-methyltransferase activity	Catalysis of the reaction: L-glutamate + methylammonium = N-methyl-L-glutamate + NH(4)(+).	tmpzr1t_l9r_go_relaxed.owl	methylamine:L-glutamate N-methyltransferase activity|N-methylglutamate synthase activity|methylamine-glutamate methyltransferase activity				EC:2.1.1.21|KEGG_REACTION:R01586|RHEA:15837|MetaCyc:2.1.1.21-RXN									molecular_function											owl:Class	
GO:0070012	biolink:NamedThing	oligopeptidase activity	Catalysis of the hydrolysis of a peptide bond in an oligopeptide, i.e. a molecule containing a small number (2 to 20) of amino acid residues connected by peptide bonds.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0033871	biolink:NamedThing	[heparan sulfate]-glucosamine 3-sulfotransferase 2 activity	Catalysis of the reaction: 3'-phosphoadenylyl sulfate + [heparan sulfate]-glucosamine = adenosine 3',5'-bisphosphate + [heparan sulfate]-glucosamine 3-sulfate; modifies selected glucosamine residues preceded by GlcA2S.	tmpzr1t_l9r_go_relaxed.owl	glucosaminyl 3-O-sulfotransferase 2 activity|3-OST-2|heparin-glucosamine 3-sulfotransferase 2 activity|3'-phosphoadenylyl-sulfate:[heparan sulfate]-glucosamine 3-sulfotransferase activity|glucosaminyl 3-O-sulfotransferase activity|heparan sulfate D-glucosaminyl 3-O-sulfotransferase activity|heparan sulfate D-glucosaminyl 3-O-sulfotransferase 2 activity|isoform/isozyme 2 (3-OST-2, HS3ST2)				MetaCyc:2.8.2.29-RXN|EC:2.8.2.29									molecular_function											owl:Class	
GO:0098942	biolink:NamedThing	retrograde trans-synaptic signaling by trans-synaptic protein complex	Cell-cell signaling from postsynapse to presynapse, across the synaptic cleft, mediated by trans-synaptic protein complex.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1990511	biolink:NamedThing	piRNA biosynthetic process	The chemical reactions and pathways resulting in the formation of piRNAs, Piwi-associated RNAs, a class of 24- to 30-nucleotide RNA derived from repeat or complex DNA sequence elements and processed by a Dicer-independent mechanism.	tmpzr1t_l9r_go_relaxed.owl	Piwi-associated RNA biosynthetic process							kmv	2014-10-07T13:47:32Z					biological_process											owl:Class	
GO:0004113	biolink:NamedThing	2',3'-cyclic-nucleotide 3'-phosphodiesterase activity	Catalysis of the reaction: nucleoside 2',3'-cyclic phosphate + H2O = nucleoside 2'-phosphate.	tmpzr1t_l9r_go_relaxed.owl	2',3'-cyclic nucleotide 3'-phosphohydrolase activity|2',3'-cyclic nucleotide 3'-phosphodiesterase activity|cyclic 2',3'-nucleotide 3'-phosphodiesterase activity|cyclic-CMP phosphodiesterase activity|nucleoside-2',3'-cyclic-phosphate 2'-nucleotidohydrolase activity|CNPase activity|2',3'-cyclic AMP phosphodiesterase activity|2',3'-cyclic nucleoside monophosphate phosphodiesterase|2':3'-cyclic nucleotide 3'-phosphodiesterase activity|cyclic 2',3'-nucleotide phosphodiesterase|2',3'-cyclic nucleotide phosphohydrolase|2':3'-CNMP-3'-ase activity				MetaCyc:3.1.4.37-RXN|EC:3.1.4.37|RHEA:14489									molecular_function											owl:Class	
GO:0019656	biolink:NamedThing	glucose catabolic process to D-lactate and ethanol	The anaerobic chemical reactions and pathways resulting in the enzymatic breakdown of D-glucose to D-lactate and ethanol, yielding energy in the form of adenosine triphosphate (ATP) at the rate of one ATP per glucose molecule.	tmpzr1t_l9r_go_relaxed.owl	heterolactate fermentation|heterofermentation|heterofermentative lactate fermentation|glucose fermentation to D-lactate and ethanol|heterofermentative pathway|heterolactic fermentation				MetaCyc:P122-PWY									biological_process											owl:Class	
GO:0032001	biolink:NamedThing	1,4-alpha-glucan 6-alpha-glucosyltransferase activity	Catalysis of the transfer an alpha-D-glucosyl residue in a (1->4)-alpha-D-glucan to the primary hydroxy group of glucose, free or combined in a (1->4)-alpha-D-glucan.	tmpzr1t_l9r_go_relaxed.owl	1,4-alpha-D-glucan 6-alpha-D-glucosyltransferase activity|D-glucosyltransferase|oligoglucan-branching glycosyltransferase activity|1,4-alpha-D-glucan:1,4-alpha-D-glucan(D-glucose) 6-alpha-D-glucosyltransferase activity|T-enzyme				EC:2.4.1.24|MetaCyc:2.4.1.24-RXN									molecular_function											owl:Class	
GO:0001111	biolink:NamedThing	promoter clearance from RNA polymerase II promoter	Any process involved in the transition from the initiation to the elongation phases of transcription by RNA polymerase II, generally including a conformational change from the initiation conformation to the elongation conformation. Promoter clearance often involves breaking contact with transcription factors involved only in the initiation phase and making contacts with elongation specific factors.	tmpzr1t_l9r_go_relaxed.owl	promoter escape from RNA polymerase II promoter							krc	2010-12-01T03:09:31Z					biological_process											owl:Class	
GO:2000261	biolink:NamedThing	negative regulation of blood coagulation, common pathway	Any process that stops, prevents or reduces the frequency, rate or extent of blood coagulation, common pathway.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-11-23T11:42:44Z					biological_process											owl:Class	
GO:1905523	biolink:NamedThing	positive regulation of macrophage migration	Any process that activates or increases the frequency, rate or extent of macrophage migration.	tmpzr1t_l9r_go_relaxed.owl	activation of macrophage migration|up-regulation of macrophage migration|up regulation of macrophage migration|upregulation of macrophage migration							sl	2016-10-03T15:29:21Z					biological_process											owl:Class	
GO:1904717	biolink:NamedThing	regulation of AMPA glutamate receptor clustering	Any process that modulates the frequency, rate or extent of AMPA glutamate receptor clustering.	tmpzr1t_l9r_go_relaxed.owl	regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor clustering|regulation of AMPA receptor clustering							hjd	2015-10-07T19:32:11Z					biological_process											owl:Class	
GO:0098897	biolink:NamedThing	spine apparatus membrane	The lipid bilayer surrounding the spine apparatus.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0010031	biolink:NamedThing	circumnutation	The organismal movement by which the tip of a plant organ follows a spiral pattern as a consequence of growth.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0019461	biolink:NamedThing	glutamine catabolic process to fumarate, using glutamate synthase (NADPH)	The chemical reactions and pathways resulting in the breakdown of glutamine into fumarate, beginning with the conversion of glutamine to glutamate catalyzed by the enzyme glutamate synthase (NADPH) (EC:1.4.1.13).	tmpzr1t_l9r_go_relaxed.owl	glutamate catabolic process to fumarate, using glutamate synthase (NADPH)|glutamine breakdown to fumarate, using glutamate synthase (NADPH)|glutamine degradation to fumarate, using glutamate synthase (NADPH)				MetaCyc:GLUTAMINEFUM-PWY									biological_process											owl:Class	
GO:0031878	biolink:NamedThing	type 1 somatostatin receptor binding	Binding to a type 1 somatostatin receptor.	tmpzr1t_l9r_go_relaxed.owl	type 1 somatostatin receptor ligand													molecular_function											owl:Class	
GO:0018377	biolink:NamedThing	protein myristoylation	The covalent attachment of a myristoyl group to a protein.	tmpzr1t_l9r_go_relaxed.owl	protein amino acid myristoylation											GO:0018319		biological_process											owl:Class	
GO:0046239	biolink:NamedThing	phthalate catabolic process	The chemical reactions and pathways resulting in the breakdown of phthalate, the anion of phthalic acid.	tmpzr1t_l9r_go_relaxed.owl	phthalate breakdown|phthalate catabolism|phthalate degradation													biological_process											owl:Class	
GO:0008234	biolink:NamedThing	cysteine-type peptidase activity	Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile.	tmpzr1t_l9r_go_relaxed.owl	cysteine protease activity|thiol protease activity				Reactome:R-HSA-2022381|Reactome:R-HSA-5660752|Reactome:R-HSA-2467809|Reactome:R-HSA-2467775							GO:0004220		molecular_function											owl:Class	
GO:0010381	biolink:NamedThing	peroxisome-chloroplast membrane tethering	The attachment of a peroxisome to a chloroplast via molecular tethers that physically bridge their respective membranes and attach them to each other. The tethering may facilitate exchange of metabolites between the organelles.	tmpzr1t_l9r_go_relaxed.owl	attachment of peroxisome to chloroplast													biological_process											owl:Class	
GO:0004925	biolink:NamedThing	prolactin receptor activity	Combining with prolactin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1903005	biolink:NamedThing	negative regulation of protein K63-linked deubiquitination	Any process that stops, prevents or reduces the frequency, rate or extent of protein K63-linked deubiquitination.	tmpzr1t_l9r_go_relaxed.owl	down regulation of protein K63-linked deubiquitination|inhibition of protein K63-linked deubiquitination|down-regulation of protein K63-linked deubiquitination|downregulation of protein K63-linked deubiquitination							bf	2014-05-12T15:40:49Z					biological_process											owl:Class	
GO:0036461	biolink:NamedThing	BLOC-2 complex binding	Binding to a BLOC-2 complex, a protein complex required for the biogenesis of specialized organelles of the endosomal-lysosomal system, such as melanosomes and platelet dense granules.	tmpzr1t_l9r_go_relaxed.owl								bf	2014-06-11T09:14:55Z					molecular_function											owl:Class	
GO:0090716	biolink:NamedThing	adaptive immune memory response	An immune response directed against a previously encountered antigen, being quicker and quantitatively better compared with the primary response.	tmpzr1t_l9r_go_relaxed.owl								tb	2016-11-11T12:32:42Z					biological_process											owl:Class	
GO:0003993	biolink:NamedThing	acid phosphatase activity	Catalysis of the reaction: an orthophosphoric monoester + H2O = an alcohol + phosphate, with an acid pH optimum.	tmpzr1t_l9r_go_relaxed.owl	acid nucleoside diphosphate phosphatase activity|uteroferrin|orthophosphoric-monoester phosphohydrolase (acid optimum)|acid phosphomonoester hydrolase activity|acid phosphomonoesterase activity|phosphate-monoester phosphohydrolase (acid optimum)|glycerophosphatase activity|phosphomonoesterase activity|acid phosphohydrolase activity|acid monophosphatase activity				Reactome:R-HSA-196950|MetaCyc:ACID-PHOSPHATASE-RXN|EC:3.1.3.2									molecular_function											owl:Class	
GO:0043580	biolink:NamedThing	periplasmic space organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the periplasmic space, the region between the inner (cytoplasmic) and outer membrane in Gram-negative bacteria, or the inner membrane and cell wall in fungi.	tmpzr1t_l9r_go_relaxed.owl	periplasmic space organisation|periplasmic space organization and biogenesis													biological_process											owl:Class	
GO:0033472	biolink:NamedThing	GDP-L-galactose biosynthetic process	The chemical reactions and pathways resulting in the formation of GDP-L-galactose, a substance composed of L-galactose in glycosidic linkage with guanosine diphosphate.	tmpzr1t_l9r_go_relaxed.owl	GDP-L-galactose anabolism|GDP-L-galactose formation|GDP-L-galactose synthesis|GDP-L-galactose biosynthesis				MetaCyc:PWY-5115									biological_process											owl:Class	
GO:2000223	biolink:NamedThing	regulation of BMP signaling pathway involved in heart jogging	Any process that modulates the frequency, rate or extent of BMP signaling pathway involved in heart jogging.	tmpzr1t_l9r_go_relaxed.owl	regulation of BMP signalling pathway involved in heart jogging pathway involved in somitogenesis							vk	2010-11-04T02:44:01Z					biological_process											owl:Class	
GO:0000085	biolink:NamedThing	mitotic G2 phase	The cell cycle 'gap' phase which is the interval between the completion of DNA synthesis and the beginning of DNA segregation by mitosis.	tmpzr1t_l9r_go_relaxed.owl	G2 phase of mitotic cell cycle					Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).								biological_process											owl:Class	
GO:0002592	biolink:NamedThing	regulation of antigen processing and presentation via MHC class Ib	Any process that modulates the frequency, rate, or extent of antigen processing and presentation of antigen via MHC class Ib.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0005680	biolink:NamedThing	anaphase-promoting complex	A ubiquitin ligase complex that degrades mitotic cyclins and anaphase inhibitory protein, thereby triggering sister chromatid separation and exit from mitosis. Substrate recognition by APC occurs through degradation signals, the most common of which is termed the Dbox degradation motif, originally discovered in cyclin B.	tmpzr1t_l9r_go_relaxed.owl	APC|cyclosome|anaphase promoting complex				Wikipedia:Anaphase-promoting_complex	Note that the synonym 'APC' should not be confused with the abbreviation for the adenomatous polyposis coli gene and protein.								cellular_component											owl:Class	
GO:0031783	biolink:NamedThing	type 5 melanocortin receptor binding	Binding to a type 5 melanocortin receptor.	tmpzr1t_l9r_go_relaxed.owl	type 5 melanocortin receptor ligand													molecular_function											owl:Class	
GO:0050291	biolink:NamedThing	sphingosine N-acyltransferase activity	Catalysis of the reaction: acyl-CoA + sphingosine = CoA + N-acylsphingosine.	tmpzr1t_l9r_go_relaxed.owl	sphingosine acyltransferase activity|dihydroceramide synthase activity|ceramide synthetase activity|acyl-CoA:sphingosine N-acyltransferase activity|ceramide synthase activity				Reactome:R-HSA-428185|RHEA:23768|EC:2.3.1.24|MetaCyc:SPHINGOSINE-N-ACYLTRANSFERASE-RXN									molecular_function											owl:Class	
GO:1902356	biolink:NamedThing	oxaloacetate(2-) transmembrane transport	The directed movement of oxaloacetate(2-) across a membrane.	tmpzr1t_l9r_go_relaxed.owl								dph	2013-08-14T14:40:37Z					biological_process											owl:Class	
GO:0017103	biolink:NamedThing	UTP:galactose-1-phosphate uridylyltransferase activity	Catalysis of the reaction: alpha-D-galactose 1-phosphate + UTP = diphosphate + UDP-D-galactose.	tmpzr1t_l9r_go_relaxed.owl	UTP:hexose-1-phosphate uridylyltransferase activity|uridine diphosphate galactose pyrophosphorylase activity|UTP-hexose-1-phosphate uridylyltransferase activity|galactose 1-phosphate uridylyltransferase activity|galactose 1-phosphate uridyltransferase activity|UDPgalactose pyrophosphorylase activity|UTP:alpha-D-hexose-1-phosphate uridylyltransferase activity|Gal-1-P uridylyltransferase activity|uridine diphosphogalactose pyrophosphorylase activity|alpha-D-galactose 1-phosphate uridylyltransferase activity|galactose-1-phosphate uridylyltransferase activity				MetaCyc:UTPHEXPURIDYLYLTRANS-RXN|RHEA:14209|EC:2.7.7.10|KEGG_REACTION:R00502							GO:0003982		molecular_function											owl:Class	
GO:0102247	biolink:NamedThing	malonyl-malonyl acyl carrier protein-condensing enzyme activity	Catalysis of the reaction: 2 H+ + 2 a malonyl-[acp] <=> 2 carbon dioxide + an acetoacetyl-[acp] + a holo-[acyl-carrier protein].	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-12361									molecular_function											owl:Class	
GO:0009194	biolink:NamedThing	pyrimidine ribonucleoside diphosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of pyrimidine ribonucleoside diphosphate, a compound consisting of a pyrimidine base linked to a ribose sugar esterified with diphosphate on the sugar.	tmpzr1t_l9r_go_relaxed.owl	pyrimidine ribonucleoside diphosphate formation|pyrimidine ribonucleoside diphosphate synthesis|pyrimidine ribonucleoside diphosphate biosynthesis|pyrimidine ribonucleoside diphosphate anabolism													biological_process											owl:Class	
GO:0047087	biolink:NamedThing	protopine 6-monooxygenase activity	Catalysis of the reaction: H(+) + NADPH + O(2) + protopine = 6-hydroxyprotopine + H(2)O + NADP(+).	tmpzr1t_l9r_go_relaxed.owl	protopine 6-hydroxylase activity|protopine,NADPH:oxygen oxidoreductase (6-hydroxylating)				EC:1.14.14.98|MetaCyc:1.14.13.55-RXN|RHEA:22644|KEGG_REACTION:R04699									molecular_function											owl:Class	
GO:0046205	biolink:NamedThing	nor-spermidine catabolic process	The chemical reactions and pathways resulting in the breakdown of nor-spermidine, a compound related to spermidine, N-(3-aminopropyl)-1,4-diaminobutane.	tmpzr1t_l9r_go_relaxed.owl	nor-spermidine breakdown|nor-spermidine catabolism|nor-spermidine degradation													biological_process											owl:Class	
GO:0005483	biolink:NamedThing	soluble NSF attachment protein activity	Binding to both N-ethylmaleimide-sensitive fusion protein (NSF) and a cis-SNARE complex (i.e. a SNARE complex in which all proteins are associated with the same membrane) and increasing the ATPase activity of NSF, thereby allowing ATP hydrolysis by NSF to disassemble the cis-SNARE complex.	tmpzr1t_l9r_go_relaxed.owl	SNAP	https://github.com/geneontology/go-ontology/issues/16807												molecular_function											owl:Class	
GO:0102645	biolink:NamedThing	17(E)-cheilanthenediol synthase activity	Catalysis of the reaction: 17(E)-cheilanthenediol <=> all-trans-geranylfarnesol + H2O.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-15758									molecular_function											owl:Class	
GO:0060962	biolink:NamedThing	regulation of ribosomal protein gene transcription by RNA polymerase II	Any process that modulates the frequency, rate or extent of the synthesis of RNA from ribosomal protein genes mediated by RNA polymerase II.	tmpzr1t_l9r_go_relaxed.owl	regulation of ribosomal protein gene transcription from RNA polymerase II promoter							dph	2009-10-05T03:00:40Z					biological_process											owl:Class	
GO:0140656	biolink:NamedThing	endodeoxyribonuclease activator activity	Binds to and increases the activity of an endodeoxyribonuclease.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/21574						pg	2021-06-10T13:31:54Z					molecular_function											owl:Class	
GO:1904867	biolink:NamedThing	protein localization to Cajal body	A process in which a protein is transported to, or maintained in, a location within a Cajal body.	tmpzr1t_l9r_go_relaxed.owl	protein localisation to Cajal body|protein localisation in Cajal body|protein localization in Cajal body							tb	2015-12-17T21:48:18Z					biological_process											owl:Class	
GO:1903405	biolink:NamedThing	protein localization to nuclear body	A process in which a protein is transported to, or maintained in, a location within a nuclear body.	tmpzr1t_l9r_go_relaxed.owl	protein localization in nuclear body|protein localisation to nuclear body|protein localisation in nuclear body							mah	2014-09-01T13:57:11Z					biological_process											owl:Class	
GO:0009759	biolink:NamedThing	indole glucosinolate biosynthetic process	The chemical reactions and pathways resulting in the formation of indole glucosinolates, sulfur-containing compounds that have a common structure linked to an R group derived from tryptophan.	tmpzr1t_l9r_go_relaxed.owl	indole glucosinolate biosynthesis|indole glucosinolate anabolism|indole glucosinolate synthesis|indole glucosinolate formation													biological_process											owl:Class	
GO:0140238	biolink:NamedThing	presynaptic endocytosis	A vesicle-mediated transport process in which the presynapse take up external materials or membrane constituents by the invagination of a small region of the plasma membrane to form a new membrane-bounded vesicle.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/synapse/issues/230				Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.		pg	2018-07-15T07:33:55Z					biological_process											owl:Class	
GO:0042340	biolink:NamedThing	keratan sulfate catabolic process	The chemical reactions and pathways resulting in the breakdown of keratan sulfate, a glycosaminoglycan with repeat units consisting of beta-1,4-linked D-galactopyranosyl-beta-(1,4)-N-acetyl-D-glucosamine 6-sulfate and with variable amounts of fucose, sialic acid and mannose units; keratan sulfate chains are covalently linked by a glycosidic attachment through the trisaccharide galactosyl-galactosyl-xylose to peptidyl-threonine or serine residues.	tmpzr1t_l9r_go_relaxed.owl	keratan sulfate catabolism|keratan sulphate catabolism|keratan sulfate degradation|keratan sulfate breakdown|keratan sulphate catabolic process													biological_process											owl:Class	
GO:0043749	biolink:NamedThing	phenol, water dikinase activity	Catalysis of the reaction: phenol + MgATP + H2O = phenylphosphate + MgAMP + orthophosphate.	tmpzr1t_l9r_go_relaxed.owl	ATP:phenol:water phosphotransferase activity|phenol:water dikinase activity|phenylphosphate synthase activity				EC:2.7.9.-									molecular_function											owl:Class	
GO:0018103	biolink:NamedThing	protein C-linked glycosylation	A protein glycosylation process in which a carbohydrate or carbohydrate derivative unit is added to a protein via a C atom.	tmpzr1t_l9r_go_relaxed.owl	protein amino acid C-linked glycosylation				RESID:AA0217									biological_process											owl:Class	
GO:0060165	biolink:NamedThing	regulation of timing of subpallium neuron differentiation	The process controlling the timing and/or rate at which a relatively unspecialized cell in the subpallium acquires features of a neuron. The subpallium is the base region of the telencephalon.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0060164	biolink:NamedThing	regulation of timing of neuron differentiation	The process controlling the activation and/or rate at which a relatively unspecialized cell acquires features of a neuron.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0031873	biolink:NamedThing	type 2 proteinase activated receptor binding	Binding to a type 2 proteinase activated receptor.	tmpzr1t_l9r_go_relaxed.owl	type 2 proteinase activated receptor ligand													molecular_function											owl:Class	
GO:1900638	biolink:NamedThing	negative regulation of asperfuranone biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of asperfuranone biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of asperfuranone anabolism|down regulation of asperfuranone anabolism|negative regulation of asperfuranone formation|down regulation of asperfuranone formation|down-regulation of asperfuranone biosynthesis|inhibition of asperfuranone anabolism|downregulation of asperfuranone synthesis|down-regulation of asperfuranone synthesis|downregulation of asperfuranone anabolism|down-regulation of asperfuranone formation|down-regulation of asperfuranone biosynthetic process|negative regulation of asperfuranone synthesis|negative regulation of asperfuranone anabolism|negative regulation of asperfuranone biosynthesis|down regulation of asperfuranone biosynthesis|inhibition of asperfuranone biosynthetic process|down regulation of asperfuranone synthesis|inhibition of asperfuranone synthesis|inhibition of asperfuranone formation|inhibition of asperfuranone biosynthesis|downregulation of asperfuranone biosynthesis|down regulation of asperfuranone biosynthetic process|downregulation of asperfuranone biosynthetic process|downregulation of asperfuranone formation							di	2012-05-22T03:50:16Z					biological_process											owl:Class	
GO:0097570	biolink:NamedThing	cyst wall	The specialized envelope lying outside the cell membrane of a cyst. A cyst is a resting or dormant stage of a microorganism, usually a bacterium or a protist or rarely an invertebrate animal, that helps the organism to survive in unfavorable environmental conditions. In protists such as protozoan parasites alternating cystic- and non-cystic stages, the cyst wall is usually composed of carbohydrates and proteins.	tmpzr1t_l9r_go_relaxed.owl								pr	2014-02-18T10:25:53Z					cellular_component											owl:Class	
GO:0002590	biolink:NamedThing	negative regulation of antigen processing and presentation of peptide antigen via MHC class I	Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class I.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of antigen processing and presentation of peptide antigen via MHC class I|down regulation of antigen processing and presentation of peptide antigen via MHC class I|negative regulation of peptide antigen processing and presentation via MHC class I|downregulation of antigen processing and presentation of peptide antigen via MHC class I|inhibition of antigen processing and presentation of peptide antigen via MHC class I													biological_process											owl:Class	
GO:1905214	biolink:NamedThing	regulation of RNA binding	Any process that modulates the frequency, rate or extent of RNA binding.	tmpzr1t_l9r_go_relaxed.owl								bf	2016-06-06T10:20:56Z					biological_process											owl:Class	
GO:0008112	biolink:NamedThing	nicotinamide N-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine(1+) + nicotinamide = 1-methylnicotinamide + S-adenosyl-L-homocysteine.	tmpzr1t_l9r_go_relaxed.owl	S-adenosyl-L-methionine:nicotinamide N-methyltransferase activity|nicotinamide methyltransferase activity				MetaCyc:NICOTINAMIDE-N-METHYLTRANSFERASE-RXN|RHEA:23884|Reactome:R-HSA-5359451|KEGG_REACTION:R01269|EC:2.1.1.1									molecular_function											owl:Class	
GO:0019956	biolink:NamedThing	chemokine binding	Binding to a chemokine. Chemokines are a family of small chemotactic cytokines; their name is derived from their ability to induce directed chemotaxis in nearby responsive cells. All chemokines possess a number of conserved cysteine residues involved in intramolecular disulfide bond formation. Some chemokines are considered pro-inflammatory and can be induced during an immune response to recruit cells of the immune system to a site of infection, while others are considered homeostatic and are involved in controlling the migration of cells during normal processes of tissue maintenance or development. Chemokines are found in all vertebrates, some viruses and some bacteria.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0070797	biolink:NamedThing	negative regulation of cleistothecium development	Any process that stops, prevents, or reduces the frequency, rate or extent of cleistothecium development, a process that leads to the formation of a cleistothecium. The cleistothecium is a closed sexual fruiting body that contains ascospores in linear asci, characteristic of some filamentous Ascomycete fungi such as members of the genera Aspergillus and Emericella.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-07-08T03:36:12Z					biological_process											owl:Class	
GO:1902442	biolink:NamedThing	regulation of ripoptosome assembly involved in necroptotic process	Any process that modulates the frequency, rate or extent of ripoptosome assembly involved in a necroptotic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of ripoptosome assembly involved in necroptosis							dph	2013-10-10T17:51:33Z					biological_process											owl:Class	
GO:0002157	biolink:NamedThing	positive regulation of thyroid hormone mediated signaling pathway	Any process that increases the frequency, rate or extent of thyroid hormone mediated signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of thyroid hormone mediated signalling pathway							hjd	2009-11-19T12:42:57Z					biological_process											owl:Class	
GO:0034771	biolink:NamedThing	histone H4-K20 monomethylation	The modification of histone H4 by addition of one methyl group to lysine at position 20 of the histone.	tmpzr1t_l9r_go_relaxed.owl	histone lysine H4 K20 monomethylation|histone H4 K20 monomethylation													biological_process											owl:Class	
GO:0018026	biolink:NamedThing	peptidyl-lysine monomethylation	The methylation of peptidyl-lysine to form peptidyl-N6-methyl-L-lysine.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0076									biological_process											owl:Class	
GO:0043652	biolink:NamedThing	engulfment of apoptotic cell	The removal of the apoptotic cell by phagocytosis, by a neighboring cell or by a phagocyte.	tmpzr1t_l9r_go_relaxed.owl	engulfment of apoptotic cell corpse|engulfment of cell corpse					This term should be used to annotate gene products from the engulfing cell that facilitate phagocytosis of apoptotic cells. It should not be mistaken with GO:0070782 'phosphatidylserine exposure on apoptotic cell surface', a process occurring in apoptotic cells that acts as a signal for engulfing cells. If gene products involved in such instances of phosphatidylserine exposure are shown to have a positive effect on engulfment, they may be annotated to GO:1901076 'positive regulation of engulfment of apoptotic cell'.								biological_process											owl:Class	
GO:0043892	biolink:NamedThing	methylglyoxal reductase (NADPH-dependent) activity	Catalysis of the reaction: lactaldehyde + NADP+ = methylglyoxal + NADPH + H+.	tmpzr1t_l9r_go_relaxed.owl	lactaldehyde:NADP+ oxidoreductase activity|lactaldehyde dehydrogenase (NADP+)|Gre2				MetaCyc:RXN-8636|EC:1.1.1.283|RHEA:21748|MetaCyc:1.1.1.283-RXN									molecular_function											owl:Class	
GO:1904598	biolink:NamedThing	positive regulation of connective tissue replacement involved in inflammatory response wound healing	Any process that activates or increases the frequency, rate or extent of connective tissue replacement involved in inflammatory response wound healing.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of fibrosis during inflammatory response|activation of fibrosis during inflammatory response|upregulation of connective tissue replacement during inflammatory response|positive regulation of connective tissue replacement during inflammatory response|up-regulation of connective tissue replacement during inflammatory response|up regulation of connective tissue replacement during inflammatory response|up regulation of fibrosis during inflammatory response|positive regulation of fibrosis during inflammatory response|activation of connective tissue replacement during inflammatory response|up regulation of connective tissue replacement involved in inflammatory response wound healing|upregulation of connective tissue replacement involved in inflammatory response wound healing|up-regulation of connective tissue replacement involved in inflammatory response wound healing|upregulation of fibrosis during inflammatory response|activation of connective tissue replacement involved in inflammatory response wound healing							krc	2015-08-25T20:52:36Z					biological_process											owl:Class	
GO:0032600	biolink:NamedThing	chemokine receptor transport out of membrane raft	The directed movement of a chemokine receptor out of a membrane raft.	tmpzr1t_l9r_go_relaxed.owl	chemokine receptor transport out of lipid raft|chemokine receptor translocation out of membrane raft													biological_process											owl:Class	
GO:0032599	biolink:NamedThing	protein transport out of membrane raft	The directed movement of a protein out of a membrane raft. Membrane rafts are small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes.	tmpzr1t_l9r_go_relaxed.owl	protein transport out of lipid raft|receptor translocation out of membrane raft|protein translocation out of membrane raft|receptor transport out of membrane raft													biological_process											owl:Class	
GO:0043889	biolink:NamedThing	(S)-3-O-geranylgeranylglyceryl phosphate synthase activity	Catalysis of the alkylation of the primary hydroxyl group in (S)-glyceryl phosphate by geranylgeranyl diphosphate to form (S)-3-O-geranylgeranylglyceryl phosphate.	tmpzr1t_l9r_go_relaxed.owl	(S)-GGGP synthase activity|GGGP synthase activity|(S)-3-O-geranylgeranylglycerylphosphate synthase activity|GGGPS					This function is involved in archaeal lipid synthesis.								molecular_function											owl:Class	
GO:0035703	biolink:NamedThing	monocyte migration into blood stream	The movement of a monocyte from the bone marrow to the blood stream.	tmpzr1t_l9r_go_relaxed.owl	release of monocytes into circulation							bf	2011-03-02T11:37:54Z					biological_process											owl:Class	
GO:0016188	biolink:NamedThing	synaptic vesicle maturation	Steps required to form an initiated synaptic vesicle into a fully formed and transmissible synaptic vesicle.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1905598	biolink:NamedThing	negative regulation of low-density lipoprotein receptor activity	Any process that stops, prevents or reduces the frequency, rate or extent of low-density lipoprotein receptor activity.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of LDL receptor|down regulation of LDLR activity|downregulation of low-density lipoprotein receptor activity|down-regulation of low-density lipoprotein receptor activity|down regulation of LDL receptor|inhibition of low-density lipoprotein receptor activity|down-regulation of LDLR activity|negative regulation of LDLR activity|inhibition of LDLR activity|down-regulation of LDL receptor|down regulation of low-density lipoprotein receptor activity|downregulation of LDL receptor|inhibition of LDL receptor|downregulation of LDLR activity							nc	2016-10-26T11:53:34Z					biological_process											owl:Class	
GO:0031723	biolink:NamedThing	CXCR4 chemokine receptor binding	Binding to a CXCR4 chemokine receptor.	tmpzr1t_l9r_go_relaxed.owl	CXCR4 chemokine receptor ligand|stromal cell-derived factor 1 receptor binding													molecular_function											owl:Class	
GO:0070931	biolink:NamedThing	Golgi-associated vesicle lumen	The volume enclosed by the membrane of a Golgi-associated vesicle.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-09-16T04:26:50Z					cellular_component											owl:Class	
GO:0061566	biolink:NamedThing	CMP phosphorylation	The process of introducing a phosphate group into CMP, cytidine monophosphate, to produce CDP. Addition of two phosphate groups produces CTP.	tmpzr1t_l9r_go_relaxed.owl								dph	2013-08-01T12:52:39Z					biological_process											owl:Class	
GO:1902430	biolink:NamedThing	negative regulation of amyloid-beta formation	Any process that stops, prevents or reduces the frequency, rate or extent of amyloid-beta formation.	tmpzr1t_l9r_go_relaxed.owl	downregulation of beta-amyloid formation|negative regulation of beta-amyloid formation|down regulation of beta-amyloid formation|down-regulation of beta-amyloid formation|inhibition of beta-amyloid formation							hjd	2013-09-25T17:41:01Z					biological_process											owl:Class	
GO:0034994	biolink:NamedThing	microtubule organizing center attachment site organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a microtubule organizing center attachment site. A microtubule organizing center attachment site is a region of the nuclear envelope to which a microtubule organizing center (MTOC) attaches.	tmpzr1t_l9r_go_relaxed.owl	microtubule organising centre attachment site organisation|MAS organization|MTOC attachment site organization													biological_process											owl:Class	
GO:0047235	biolink:NamedThing	sucrose 6F-alpha-galactotransferase activity	Catalysis of the reaction: sucrose + UDP-galactose = 6F-alpha-D-galactosylsucrose + UDP.	tmpzr1t_l9r_go_relaxed.owl	uridine diphosphogalactose-sucrose 6F-alpha-galactosyltransferase activity|UDPgalactose:sucrose 6fru-alpha-galactosyltransferase activity|UDP-galactose:sucrose 6F-alpha-D-galactosyltransferase activity|sucrose 6(F)-alpha-galactosyltransferase activity|sucrose 6F-alpha-galactosyltransferase activity|UDPgalactose:sucrose 6F-alpha-D-galactosyltransferase activity				MetaCyc:2.4.1.167-RXN|RHEA:10088|EC:2.4.1.167									molecular_function											owl:Class	
GO:0005995	biolink:NamedThing	melibiose catabolic process	The chemical reactions and pathways resulting in the breakdown of melibiose, the disaccharide 6-O-alpha-D-galactopyranosyl-D-glucose.	tmpzr1t_l9r_go_relaxed.owl	melibiose catabolism|melibiose breakdown|melibiose degradation													biological_process											owl:Class	
GO:0140612	biolink:NamedThing	DNA damage sensor activity	A molecule that recognises toxic DNA structures, for example, double-strand breaks or collapsed replication forks, and initiates a signalling response.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/19051						pg	2021-03-03T18:11:17Z					molecular_function											owl:Class	
GO:0005138	biolink:NamedThing	interleukin-6 receptor binding	Binding to an interleukin-6 receptor.	tmpzr1t_l9r_go_relaxed.owl	IL-6|interleukin-6 receptor ligand													molecular_function											owl:Class	
GO:0150168	biolink:NamedThing	negative regulation of histone H3-K4 acetylation	Any process that stops, prevents or reduces the frequency, rate or extent of histone H3-K4 acetylation.	tmpzr1t_l9r_go_relaxed.owl								bc	2020-01-14T12:34:01Z					biological_process											owl:Class	
GO:0030320	biolink:NamedThing	cellular monovalent inorganic anion homeostasis	Any process involved in the maintenance of an internal steady state of monovalent inorganic anions at the level of a cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0030002	biolink:NamedThing	cellular anion homeostasis	Any process involved in the maintenance of an internal steady state of anions at the level of a cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0048648	biolink:NamedThing	caste determination	The process in which individuals, having the potential to develop any of several distinct developmental paths, have their individual developmental fate determined in response to environmental and/or genetic cues. Individuals with distinct developmental fates perform different functions in a colony of social insects.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0102145	biolink:NamedThing	(3R)-(E)-nerolidol synthase activity	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate + H2O <=> (3R,6E)-nerolidol + diphosphoric acid.	tmpzr1t_l9r_go_relaxed.owl					RHEA:27534|MetaCyc:RXN-11575|EC:4.2.3.49									molecular_function											owl:Class	
GO:0032124	biolink:NamedThing	macronucleus organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the macronucleus.	tmpzr1t_l9r_go_relaxed.owl	macronuclear organization and biogenesis|macronuclear organization|macronucleus organisation													biological_process											owl:Class	
GO:0039629	biolink:NamedThing	T=219 icosahedral capsid	The protein coat that surrounds the infective nucleic acid in some virus particles where the subunits (capsomeres) are arranged to form an icosahedron with T=219 symmetry. T=219 icosahedral capsid is composed of 12 pentameric and 2180 hexameric capsomeres for a total of 13140 capsid proteins.	tmpzr1t_l9r_go_relaxed.owl								bf	2012-08-03T16:29:00Z					cellular_component											owl:Class	
GO:0000227	biolink:NamedThing	oxaloacetate secondary active transmembrane transporter activity	Enables the transfer of oxaloacetate from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters.	tmpzr1t_l9r_go_relaxed.owl	oxaloacetate carrier activity													molecular_function											owl:Class	
GO:1900857	biolink:NamedThing	positive regulation of fumitremorgin B biosynthetic process	Any process that activates or increases the frequency, rate or extent of fumitremorgin B biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	upregulation of fumitremorgin B biosynthetic process|up-regulation of fumitremorgin B biosynthetic process|up regulation of fumitremorgin B biosynthetic process							di	2012-06-07T09:51:09Z					biological_process											owl:Class	
GO:1905516	biolink:NamedThing	positive regulation of fertilization	Any process that activates or increases the frequency, rate or extent of fertilization.	tmpzr1t_l9r_go_relaxed.owl	upregulation of syngamy|upregulation of fertilization|activation of syngamy|up regulation of fertilization|up regulation of syngamy|activation of fertilization|up-regulation of syngamy|positive regulation of syngamy|up-regulation of fertilization							pr	2016-09-30T14:32:32Z					biological_process											owl:Class	
GO:0080025	biolink:NamedThing	phosphatidylinositol-3,5-bisphosphate binding	Binding to phosphatidylinositol-3,5-bisphosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 3' and 5' positions.	tmpzr1t_l9r_go_relaxed.owl	PtdIns(3,5)P2 binding													molecular_function											owl:Class	
GO:0047558	biolink:NamedThing	3-cyanoalanine hydratase activity	Catalysis of the reaction: L-asparagine = 3-cyano-L-alanine + H(2)O + H(+).	tmpzr1t_l9r_go_relaxed.owl	L-asparagine hydro-lyase (3-cyanoalanine-forming)|beta-CNAla hydrolase activity|L-asparagine hydro-lyase activity|beta-cyanoalanine hydratase activity|beta-cyanoalanine hydrolase activity|beta-CNA nitrilase activity				RHEA:15385|KEGG_REACTION:R01267|MetaCyc:3-CYANOALANINE-HYDRATASE-RXN|EC:4.2.1.65									molecular_function											owl:Class	
GO:0061772	biolink:NamedThing	xenobiotic transport across blood-nerve barrier	The directed movement of a xenobiotic through the blood-nerve barrier.	tmpzr1t_l9r_go_relaxed.owl	drug transport across blood-nerve barrier|drug transport across perineurial barrier							dph	2016-07-09T09:59:59Z					biological_process											owl:Class	
GO:0043027	biolink:NamedThing	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	Binds to and stops, prevents or reduces the activity of a cysteine-type endopeptidase involved in the apoptotic process.	tmpzr1t_l9r_go_relaxed.owl	caspase inhibitor activity													molecular_function											owl:Class	
GO:0019168	biolink:NamedThing	2-octaprenylphenol hydroxylase activity	Catalysis of the reaction: 2-octaprenylphenol + NADPH + O2 + H+ = 2-octaprenyl-6-hydroxyphenol + NADP+ + H2O.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:2-OCTAPRENYLPHENOL-HYDROX-RXN|RHEA:27790									molecular_function											owl:Class	
GO:0002372	biolink:NamedThing	myeloid dendritic cell cytokine production	Any process that contributes to cytokine production by a myeloid dendritic cell.	tmpzr1t_l9r_go_relaxed.owl						Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.								biological_process											owl:Class	
GO:0008193	biolink:NamedThing	tRNA guanylyltransferase activity	Catalysis of the posttranscriptional addition of a guanyl residue to the 5' end of a tRNA molecule; observed for His tRNAs.	tmpzr1t_l9r_go_relaxed.owl					EC:2.7.7.79|RHEA:54564									molecular_function											owl:Class	
GO:0008192	biolink:NamedThing	RNA guanylyltransferase activity	Catalysis of the posttranscriptional addition of a guanyl residue to the 5' end of an RNA molecule.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0120011	biolink:NamedThing	intermembrane sterol transfer	The transport of sterols between membranes in which a sterol molecule is transported through an aqueous phase from the outer leaflet of a donor membrane to the outer leaflet of an acceptor membrane. This process does not require metabolic energy and can be either spontaneous or mediated by lipid transfer proteins (LTPs).	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/12329						krc	2017-03-16T22:15:40Z					biological_process											owl:Class	
GO:0043279	biolink:NamedThing	response to alkaloid	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alkaloid stimulus. Alkaloids are a large group of nitrogenous substances found in naturally in plants, many of which have extracts that are pharmacologically active.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:2000191	biolink:NamedThing	regulation of fatty acid transport	Any process that modulates the frequency, rate or extent of fatty acid transport.	tmpzr1t_l9r_go_relaxed.owl								rl	2010-10-18T10:37:13Z					biological_process											owl:Class	
GO:0005052	biolink:NamedThing	peroxisome matrix targeting signal-1 binding	Binding to a type 1 peroxisome targeting signal, a tripeptide with the consensus sequence (S/A/C)-(K/R/H)-L.	tmpzr1t_l9r_go_relaxed.owl	PTS1 binding|peroxisome targeting signal-1 receptor|peroxisome targeting signal-1 binding|peroxisomal targeting signal 1 (PTS1) binding|PTS1 receptor|PEX5													molecular_function											owl:Class	
GO:0000268	biolink:NamedThing	peroxisome targeting sequence binding	Binding to a peroxisomal targeting sequence, a sequence of amino acids within a protein that acts as a signal for the localization of a protein into the peroxisome.	tmpzr1t_l9r_go_relaxed.owl	PTS receptor|peroxisome targeting signal receptor|PTS binding											GO:0005051		molecular_function											owl:Class	
GO:0050835	biolink:NamedThing	iron incorporation into iron-sulfur cluster via tris-L-cysteinyl S-adenosylmethion-N,O-diyl tetrairon tetrasulfide	The incorporation of iron into a 4Fe-4S iron-sulfur cluster via tris-L-cysteinyl S-adenosylmethion-N,O-diyl tetrairon tetrasulfide.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0356									biological_process											owl:Class	
GO:0033932	biolink:NamedThing	1,3-alpha-L-fucosidase activity	Catalysis of the hydrolysis of (1->3) linkages between alpha-L-fucose and N-acetylglucosamine residues in glycoproteins.	tmpzr1t_l9r_go_relaxed.owl	almond emulsin fucosidase I activity|3-alpha-L-fucosyl-N-acetylglucosaminyl-glycoprotein fucohydrolase activity				MetaCyc:3.2.1.111-RXN|EC:3.2.1.111									molecular_function											owl:Class	
GO:0004560	biolink:NamedThing	alpha-L-fucosidase activity	Catalysis of the reaction: an alpha-L-fucoside + H2O = an alcohol + L-fucose.	tmpzr1t_l9r_go_relaxed.owl	alpha-L-fucoside fucohydrolase activity|alpha-fucosidase activity				RHEA:12288|EC:3.2.1.51|MetaCyc:ALPHA-L-FUCOSIDASE-RXN|Reactome:R-HSA-5693807									molecular_function											owl:Class	
GO:0018479	biolink:NamedThing	benzaldehyde dehydrogenase (NAD+) activity	Catalysis of the reaction: benzaldehyde + NAD+ + H2O = benzoate + NADH + H+.	tmpzr1t_l9r_go_relaxed.owl	benzaldehyde (NAD) dehydrogenase activity|benzaldehyde:NAD+ oxidoreductase activity				UM-BBD_reactionID:r0269|MetaCyc:BENZALDEHYDE-DEHYDROGENASE-NAD+-RXN|RHEA:11840|EC:1.2.1.28									molecular_function											owl:Class	
GO:0034126	biolink:NamedThing	positive regulation of MyD88-dependent toll-like receptor signaling pathway	Any process that activates or increases the frequency, rate, or extent of MyD88-dependent toll-like receptor signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of MyD88-dependent toll-like receptor signalling pathway|positive regulation of MyD88-dependent TLR signaling pathway													biological_process											owl:Class	
GO:1990194	biolink:NamedThing	cytoplasmic U snRNP body assembly	The aggregation, arrangement and bonding together of proteins and RNA molecules to form a cytoplasmic U snRNP body.	tmpzr1t_l9r_go_relaxed.owl	U body assembly							tb	2013-09-12T21:54:20Z					biological_process											owl:Class	
GO:0044740	biolink:NamedThing	negative regulation of sensory perception of pain in other organism	A process that negatively regulates the sensory perception of pain in a different organism.	tmpzr1t_l9r_go_relaxed.owl	inhibition of sensory perception of pain in another organism							jl	2012-11-07T13:43:10Z					biological_process											owl:Class	
GO:0044465	biolink:NamedThing	modulation of sensory perception of pain in other organism	A process that modulates the frequency, rate or extent of the sensory perception of pain, the series of events required for an organism to receive a painful stimulus, convert it to a molecular signal, and recognize and characterize the signal, in a different organism.	tmpzr1t_l9r_go_relaxed.owl	regulation of sensory perception of pain in another organism							jl	2012-01-12T03:14:19Z					biological_process											owl:Class	
GO:0080042	biolink:NamedThing	ADP-glucose pyrophosphohydrolase activity	Catalysis of the reaction: ADP-glucose + H2O = AMP + glucose-1-phosphate.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0033772	biolink:NamedThing	flavonoid 3',5'-hydroxylase activity	Catalysis of the reactions: a flavanone + NADPH + H+ + O2 = a 3'-hydroxyflavanone + NADP+ + H2O, and a 3'-hydroxyflavanone + NADPH + H+ + O2 = a 3',5'-dihydroxyflavanone + NADP+ + H2O.	tmpzr1t_l9r_go_relaxed.owl	F3'5'H|F3',5'H|flavanone,NADPH:oxygen oxidoreductase activity				MetaCyc:RXN-8671|EC:1.14.14.81|MetaCyc:RXN-7783|RHEA:55448									molecular_function											owl:Class	
GO:1905504	biolink:NamedThing	negative regulation of motile cilium assembly	Any process that stops, prevents or reduces the frequency, rate or extent of motile cilium assembly.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of motile primary cilia assembly|down-regulation of nodal cilium formation|negative regulation of motile primary cilium assembly|negative regulation of motile primary cilia formation|downregulation of nodal cilium formation|down regulation of motile primary cilium assembly|down-regulation of motile primary cilium formation|downregulation of motile primary cilium assembly|inhibition of nodal cilium formation|downregulation of motile primary cilia assembly|negative regulation of motile primary cilia assembly|down regulation of motile primary cilia formation|negative regulation of nodal cilium assembly|down regulation of nodal cilium formation|down-regulation of nodal cilium assembly|inhibition of motile primary cilium formation|downregulation of nodal cilium assembly|inhibition of motile primary cilia formation|inhibition of motile primary cilia assembly|downregulation of motile primary cilia formation|down regulation of nodal cilium assembly|down regulation of motile primary cilia assembly|inhibition of nodal cilium assembly|down regulation of motile primary cilium formation|down-regulation of motile primary cilium assembly|inhibition of motile primary cilium assembly|downregulation of motile primary cilium formation|negative regulation of motile primary cilium formation|down-regulation of motile primary cilia formation|negative regulation of nodal cilium formation							krc	2016-09-27T18:27:55Z					biological_process											owl:Class	
GO:0021677	biolink:NamedThing	rhombomere 8 formation	The process that gives rise to rhombomere 8. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0070347	biolink:NamedThing	regulation of brown fat cell proliferation	Any process that modulates the frequency, rate or extent of brown fat cell proliferation.	tmpzr1t_l9r_go_relaxed.owl	regulation of brown adipose cell proliferation|regulation of brown adipocyte proliferation													biological_process											owl:Class	
GO:0070344	biolink:NamedThing	regulation of fat cell proliferation	Any process that modulates the frequency, rate or extent of fat cell proliferation.	tmpzr1t_l9r_go_relaxed.owl	regulation of adipocyte proliferation|regulation of adipose cell proliferation													biological_process											owl:Class	
GO:0021633	biolink:NamedThing	optic nerve structural organization	The process that contributes to the act of creating the structural organization of the optic nerve. This process pertains to the physical shaping of a rudimentary structure. The sensory optic nerve originates from the bipolar cells of the retina and conducts visual information to the brainstem. The optic nerve exits the back of the eye in the orbit, enters the optic canal, and enters the central nervous system at the optic chiasm (crossing) where the nerve fibers become the optic tract just prior to entering the hindbrain.	tmpzr1t_l9r_go_relaxed.owl	CN II structural organization|optic nerve structural organisation													biological_process											owl:Class	
GO:0006244	biolink:NamedThing	pyrimidine nucleotide catabolic process	The chemical reactions and pathways resulting in the breakdown of a pyrimidine nucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.	tmpzr1t_l9r_go_relaxed.owl	pyrimidine nucleotide catabolism|pyrimidine nucleotide degradation|pyrimidine nucleotide breakdown													biological_process											owl:Class	
GO:0048396	biolink:NamedThing	negative regulation of intermediate mesodermal cell fate determination	Any process that stops, prevents, or reduces the frequency, rate or extent of intermediate mesoderm cell fate determination.	tmpzr1t_l9r_go_relaxed.owl	inhibition of intermediate mesodermal cell fate determination|down regulation of intermediate mesodermal cell fate determination|downregulation of intermediate mesodermal cell fate determination|down-regulation of intermediate mesodermal cell fate determination													biological_process											owl:Class	
GO:1990935	biolink:NamedThing	splicing factor binding	Binding to a protein involved in the process of removing sections of the primary RNA transcript to form the mature form of the RNA.	tmpzr1t_l9r_go_relaxed.owl								sl	2016-03-21T21:57:20Z					molecular_function											owl:Class	
GO:1903451	biolink:NamedThing	negative regulation of G1 to G0 transition	Any process that stops, prevents or reduces the frequency, rate or extent of G1 to G0 transition.	tmpzr1t_l9r_go_relaxed.owl	inhibition of G1 to G0 transition|down-regulation of establishment of cell quiescence|downregulation of G1/G0 transition|down regulation of stationary phase|downregulation of cell cycle quiescence|inhibition of stationary phase|down-regulation of stationary phase|inhibition of cell cycle quiescence|inhibition of establishment of cell quiescence|inhibition of G1/G0 transition|down regulation of G1 to G0 transition|down regulation of cell cycle quiescence|downregulation of stationary phase|down-regulation of cell cycle quiescence|down regulation of G1/G0 transition|negative regulation of cell cycle quiescence|downregulation of establishment of cell quiescence|negative regulation of stationary phase|negative regulation of G1/G0 transition|negative regulation of establishment of cell quiescence|down regulation of establishment of cell quiescence|down-regulation of G1/G0 transition|down-regulation of G1 to G0 transition|downregulation of G1 to G0 transition							di	2014-09-19T22:23:22Z					biological_process											owl:Class	
GO:0048395	biolink:NamedThing	regulation of intermediate mesodermal cell fate determination	Any process that modulates the frequency, rate or extent of intermediate mesoderm cell fate determination.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0050198	biolink:NamedThing	pinosylvin synthase activity	Catalysis of the reaction: trans-cinnamoyl-CoA + 3 H(+) + 3 malonyl-CoA = 4 CO(2) + 4 CoA + pinosylvin.	tmpzr1t_l9r_go_relaxed.owl	malonyl-CoA:cinnamoyl-CoA malonyltransferase (cyclizing)|pine stilbene synthase activity|stilbene synthase activity				RHEA:12552|MetaCyc:PINOSYLVIN-SYNTHASE-RXN|KEGG_REACTION:R02505|EC:2.3.1.146									molecular_function											owl:Class	
GO:0035125	biolink:NamedThing	embryonic anal fin morphogenesis	The process, occurring in the embryo, by which the anatomical structures of the embryonic anal fin are generated and organized. An anal fin is an unpaired medial fin on the ventral aspect near the caudal end of a fish, which provides lateral stability while swimming.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0035122	biolink:NamedThing	embryonic medial fin morphogenesis	The process, occurring in the embryo, by which the anatomical structures of the medial fin are generated and organized. Medial fins are unpaired fins of fish, usually located dorsomedially or ventromedially and primarily used for stability while swimming.	tmpzr1t_l9r_go_relaxed.owl	embryonic unpaired fin morphogenesis													biological_process											owl:Class	
GO:0015636	biolink:NamedThing	short-chain fatty acid transmembrane transporter activity	Enables the transfer of short-chain fatty acids from one side of a membrane to the other. Short-chain fatty acids are fatty acids with a chain length of less than C6.	tmpzr1t_l9r_go_relaxed.owl	short-chain fatty acid uptake transporter activity|short-chain fatty acid transporter activity											GO:0015635		molecular_function											owl:Class	
GO:0015848	biolink:NamedThing	spermidine transport	The directed movement of spermidine, N-(3-aminopropyl)-1,4-diaminobutane, a polyamine formed by the transfer of a propylamine group from decarboxylated S-adenosylmethionine to putrescine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0018503	biolink:NamedThing	trans-1,2-dihydrodiolphenanthrene dehydrogenase activity	Catalysis of the reaction: trans-1,2-dihydrodiolphenanthrene + NAD+ = H+ + NADH + 1,2-dihydroxyphenanthrene.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0574									molecular_function											owl:Class	
GO:0006689	biolink:NamedThing	ganglioside catabolic process	The chemical reactions and pathways resulting in the breakdown of ganglioside, a ceramide oligosaccharide carrying, in addition to other sugar residues, one or more sialic residues.	tmpzr1t_l9r_go_relaxed.owl	ganglioside breakdown|ganglioside degradation|ganglioside catabolism													biological_process											owl:Class	
GO:0021849	biolink:NamedThing	neuroblast division in subventricular zone	The division of neuroblasts in the subventricular zone of the forebrain. The interneuron precursors that these cells give rise to include adult olfactory bulb interneurons and migrate tangentially.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0043217	biolink:NamedThing	myelin maintenance	The process of preserving the structure and function of mature myelin. This includes maintaining the compact structure of myelin necessary for its electrical insulating characteristics as well as the structure of non-compact regions such as Schmidt-Lantermann clefts and paranodal loops. This does not include processes responsible for maintaining the nodes of Ranvier, which are not part of the myelin sheath.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0047025	biolink:NamedThing	3-oxoacyl-[acyl-carrier-protein] reductase (NADH) activity	Catalysis of the reaction: NAD+ + OH-acyl-[acyl-carrier protein] = NADH + H+ + B-ketoacyl-[acyl-carrier protein].	tmpzr1t_l9r_go_relaxed.owl	(3R)-3-hydroxyacyl-acyl-carrier-protein:NAD+ oxidoreductase activity|3-oxoacyl-[acyl-carrier protein] reductase (NADH) activity|3-oxoacyl-acyl carrier protein (reduced nicotinamide adenine dinucleotide) reductase activity|3-oxoacyl-acyl-carrier-protein reductase (NADH)|3-oxoacyl-ACP reductase (NADH) activity				RHEA:19913|MetaCyc:1.1.1.212-RXN|EC:1.1.1.212									molecular_function											owl:Class	
GO:0032267	biolink:NamedThing	tRNA(Ile)-lysidine synthase activity	Catalysis of the ligation of lysine onto the cytidine residue present at the wobble position (usually position 34) of an AUA-specific isoleucine tRNA, to form the derivative lysidine. This modification converts both the codon specificity of tRNA(Ile) from AUG to AUA and its amino acid specificity from methionine to isoleucine.	tmpzr1t_l9r_go_relaxed.owl	tRNA(Ile)-lysidine synthetase activity|tRNA(Ile)-2-lysyl-cytidine synthase activity				EC:6.3.4.-									molecular_function											owl:Class	
GO:0010079	biolink:NamedThing	maintenance of vegetative meristem identity	The process in which an organism retains a population of vegetative meristem cells, preventing the commitment of all stem cell progeny to a differentiated cell fate.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0010074	biolink:NamedThing	maintenance of meristem identity	The process in which an organism retains a population of meristem cells, preventing the commitment of all stem cell progeny to a differentiated cell fate.	tmpzr1t_l9r_go_relaxed.owl	meristem cell maintenance|maintenance of meristem cell identity											GO:0032503		biological_process											owl:Class	
GO:0103020	biolink:NamedThing	1-deoxy-D-xylulose kinase activity	Catalysis of the reaction: 1-deoxy-D-xylulose + ATP <=> H+ + 1-deoxy-D-xylulose 5-phosphate + ADP.	tmpzr1t_l9r_go_relaxed.owl					RHEA:27990|MetaCyc:RXN0-382									molecular_function											owl:Class	
GO:0009601	biolink:NamedThing	detection of insect	The series of events in which a stimulus from an insect is received and converted into a molecular signal.	tmpzr1t_l9r_go_relaxed.owl	perception of insect													biological_process											owl:Class	
GO:0052680	biolink:NamedThing	epi-isozizaene synthase activity	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = (+)-epi-isozizaene + diphosphate.	tmpzr1t_l9r_go_relaxed.owl	(2E,6E)-farnesyl-diphosphate diphosphate-lyase [(+)-epi-isozizaene-forming] activity				KEGG_REACTION:R07830|RHEA:25992|MetaCyc:RXN-9349|EC:4.2.3.37									molecular_function											owl:Class	
GO:0102602	biolink:NamedThing	cytochrome P450 dependent 16beta-hydroxy-beta-amyrin epoxidase activity	Catalysis of the reaction: 16beta-hydroxy-beta-amyrin + O2 + H+ + NAD(P)H <=> 12,13beta-epoxy-16beta-hydroxy-beta-amyrin + H2O + NAD(P).	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-15386									molecular_function											owl:Class	
GO:0140621	biolink:NamedThing	type I pilus	A short filamentous structure on the surface of a bacterial cell distinguished from other pili by their D-mannose-sensitive agglutinatination of erythrocytes. In E. coli, type I pili consist of a short tip fibrillum made up of the adhesin protein (FimH) and two minor subunits (FimG and FimF) that is joined to the pilus rod, a homopolymer of ~1000 FimA subunits.	tmpzr1t_l9r_go_relaxed.owl	type 1 pilus|type I fimbriae|type I pili	https://github.com/geneontology/go-ontology/issues/14470						pg	2021-03-10T10:24:04Z					cellular_component											owl:Class	
GO:0005994	biolink:NamedThing	melibiose metabolic process	The chemical reactions and pathways involving melibiose, the disaccharide 6-O-alpha-D-galactopyranosyl-D-glucose.	tmpzr1t_l9r_go_relaxed.owl	melibiose metabolism													biological_process											owl:Class	
GO:0017017	biolink:NamedThing	MAP kinase tyrosine/serine/threonine phosphatase activity	Catalysis of the reaction: MAP kinase serine/threonine/tyrosine phosphate + H2O = MAP kinase serine/threonine/tyrosine + phosphate.	tmpzr1t_l9r_go_relaxed.owl	dual-specificity MAP kinase phosphatase activity													molecular_function											owl:Class	
GO:0033549	biolink:NamedThing	MAP kinase phosphatase activity	Catalysis of the reaction: a phosphorylated MAP kinase + H2O = a MAP kinase + phosphate.	tmpzr1t_l9r_go_relaxed.owl	MAPK phosphatase activity													molecular_function											owl:Class	
GO:0050535	biolink:NamedThing	beta-primeverosidase activity	Catalysis of the reaction: a 6-O-(beta-D-xylopyranosyl)-beta-D-glucopyranoside + H2O = 6-O-(beta-D-xylopyranosyl)-beta-D-glucopyranose + an alcohol.	tmpzr1t_l9r_go_relaxed.owl	6-O-(beta-D-xylopyranosyl)-beta-D-glucopyranoside 6-O-(beta-D-xylosyl)-beta-D-glucohydrolase activity|b-primeverosidase activity				MetaCyc:3.2.1.149-RXN|EC:3.2.1.149|RHEA:24480									molecular_function											owl:Class	
GO:1904919	biolink:NamedThing	transmembrane L-cystine transport from lysosomal lumen to cytosol	The directed movement of L-cystine from the lysosomal lumen across the lysosomal membrane and into the cytosol.	tmpzr1t_l9r_go_relaxed.owl								kmv	2016-01-21T16:28:02Z					biological_process											owl:Class	
GO:0090666	biolink:NamedThing	scaRNA localization to Cajal body	A process in which a small Cajal body-specific RNA is transported to, or maintained in, a Cajal body.	tmpzr1t_l9r_go_relaxed.owl								tb	2015-12-15T10:57:05Z					biological_process											owl:Class	
GO:0002355	biolink:NamedThing	detection of tumor cell	The series of events in which a stimulus from a tumor cell is received and converted into a molecular signal.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0044378	biolink:NamedThing	non-sequence-specific DNA binding, bending	The activity of binding selectively and non-covalently to DNA in a sequence-independent manner and distorting the original structure of DNA, typically a straight helix, into a bend, or increasing the bend if the original structure was intrinsically bent due to its sequence.	tmpzr1t_l9r_go_relaxed.owl	DNA bending involving non-sequence-specific DNA binding							jl	2011-12-08T02:02:13Z					molecular_function											owl:Class	
GO:0008301	biolink:NamedThing	DNA binding, bending	The activity of binding selectively and non-covalently to and distorting the original structure of DNA, typically a straight helix, into a bend, or increasing the bend if the original structure was intrinsically bent due to its sequence.	tmpzr1t_l9r_go_relaxed.owl	DNA bending involving DNA binding|DNA bending activity													molecular_function											owl:Class	
GO:0044470	biolink:NamedThing	envenomation resulting in negative regulation of blood coagulation in other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant stopping, prevention or reduction in the frequency, rate or extent of blood coagulation in the bitten organism.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-01-19T01:32:48Z					biological_process											owl:Class	
GO:0060354	biolink:NamedThing	negative regulation of cell adhesion molecule production	Any process that decreases the rate, frequency or extent of cell adhesion molecule production. Cell adhesion molecule production is the appearance of a cell adhesion molecule as a result of its biosynthesis or a decrease in its catabolism.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1904633	biolink:NamedThing	regulation of glomerular visceral epithelial cell apoptotic process	Any process that modulates the frequency, rate or extent of glomerular visceral epithelial cell apoptotic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of podocyte apoptotic process|regulation of glomerular visceral epithelial cell apoptosis|regulation of glomerular podocyte apoptotic process|regulation of podocyte apoptosis|regulation of glomerular podocyte apoptosis							sl	2015-08-28T14:14:44Z					biological_process											owl:Class	
GO:0030420	biolink:NamedThing	establishment of competence for transformation	The process in which a naturally transformable bacterium acquires the ability to take up exogenous DNA. This term should be applied only to naturally transformable bacteria, and should not be used in the context of artificially induced bacterial transformation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0035842	biolink:NamedThing	old cell tip after activation of bipolar cell growth	A cell tip which has existed for at least one complete cell cycle, and at which polarized growth occurs, which is part of a cell that has activated bipolar cell growth (i.e. in which new end take-off, NETO, has taken place). For example, in fission yeast the cell end that existed prior to cell division grows immediately after division, and contains a distinctive complement of proteins including actin cytoskeletal structures.	tmpzr1t_l9r_go_relaxed.owl	post-NETO old cell tip|post-new end take-off old cell tip|post-NETO old cell end							bf	2011-05-06T01:37:23Z					cellular_component											owl:Class	
GO:0004031	biolink:NamedThing	aldehyde oxidase activity	Catalysis of the reaction: an aldehyde + H2O + O2 = a carboxylic acid + hydrogen peroxide.	tmpzr1t_l9r_go_relaxed.owl	quinoline oxidase activity|aldehyde:oxygen oxidoreductase activity				Reactome:R-HSA-3204311|RHEA:16829|MetaCyc:ALDEHYDE-OXIDASE-RXN|EC:1.2.3.1									molecular_function											owl:Class	
GO:0008658	biolink:NamedThing	penicillin binding	Binding to penicillin, an antibiotic that contains the condensed beta-lactamthiazolidine ring system.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0045983	biolink:NamedThing	positive regulation of purine nucleobase metabolic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving purine bases.	tmpzr1t_l9r_go_relaxed.owl	upregulation of purine base metabolic process|activation of purine base metabolic process|up-regulation of purine base metabolic process|up regulation of purine base metabolic process|stimulation of purine base metabolic process|positive regulation of purine base metabolism|positive regulation of purine base metabolic process													biological_process											owl:Class	
GO:0102488	biolink:NamedThing	dTTP phosphohydrolase activity	Catalysis of the reaction: dTTP + 2 H2O = dTMP + 2 hydrogenphosphate + 2 H+.	tmpzr1t_l9r_go_relaxed.owl					EC:3.6.1.5|MetaCyc:RXN-14200									molecular_function											owl:Class	
GO:0046111	biolink:NamedThing	xanthine biosynthetic process	The chemical reactions and pathways resulting in the formation of xanthine, 2,6-dihydroxypurine, a purine formed in the metabolic breakdown of guanine but not present in nucleic acids.	tmpzr1t_l9r_go_relaxed.owl	xanthine biosynthesis|xanthine formation|xanthine anabolism|xanthine synthesis													biological_process											owl:Class	
GO:0042352	biolink:NamedThing	GDP-L-fucose salvage	The formation of GDP-L-fucose from L-fucose, without de novo synthesis. L-fucose is phosphorylated by fucokinase and then converted by fucose-1-phosphate guanylyltransferase (EC:2.7.7.30).	tmpzr1t_l9r_go_relaxed.owl	GDP-L-fucose biosynthetic process, salvage pathway|GDP-L-fucose biosynthesis, salvage pathway				MetaCyc:PWY-6									biological_process											owl:Class	
GO:0060621	biolink:NamedThing	negative regulation of cholesterol import	Any process that decreases the rate, frequency or extent of cholesterol import. Cholesterol import is the directed movement of cholesterol into a cell or organelle.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-05-18T01:46:21Z					biological_process											owl:Class	
GO:2000910	biolink:NamedThing	negative regulation of sterol import	Any process that stops, prevents or reduces the frequency, rate or extent of sterol import.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of sterol influx|negative regulation of sterol uptake							bf	2011-07-29T01:25:14Z					biological_process											owl:Class	
GO:0002052	biolink:NamedThing	positive regulation of neuroblast proliferation	Any process that activates or increases the rate of neuroblast proliferation.	tmpzr1t_l9r_go_relaxed.owl	stimulation of neuroblast proliferation|up-regulation of neuroblast proliferation|upregulation of neuroblast proliferation|activation of neuroblast proliferation|up regulation of neuroblast proliferation													biological_process											owl:Class	
GO:1901127	biolink:NamedThing	candicidin biosynthetic process	The chemical reactions and pathways resulting in the formation of candicidin.	tmpzr1t_l9r_go_relaxed.owl	candicidin anabolism|candicidin biosynthesis|candicidin synthesis|candicidin formation							yaf	2012-07-11T03:17:02Z					biological_process											owl:Class	
GO:0010430	biolink:NamedThing	fatty acid omega-oxidation	A fatty acid oxidation process in which the methyl group at the end of the fatty acid molecule (the omega carbon) is first oxidized to a hydroxyl group, then to an oxo group, and finally to a carboxyl group. The long chain dicarboxylates derived from omega-oxidation then enter the beta-oxidation pathway for further degradation.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:PWY-2724									biological_process											owl:Class	
GO:0018742	biolink:NamedThing	epoxide hydrolase B activity	Catalysis of the hydrolysis of the ether in chloro- or hydroxyepoxypropane to produce chloropropane diol or glycerol. Acts on R enantiomers.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_enzymeID:e0051|EC:3.3.2.-									molecular_function											owl:Class	
GO:0004301	biolink:NamedThing	epoxide hydrolase activity	Catalysis of the reaction: an epoxide + H2O = a glycol.	tmpzr1t_l9r_go_relaxed.owl	cytosolic epoxide hydrolase activity|trans-stilbene oxide hydrolase activity|epoxide hydratase activity|sEH|epoxide hydrase activity|aryl epoxide hydrase activity|soluble epoxide hydrolase activity|arene-oxide hydratase activity				Reactome:R-HSA-2161961|Reactome:R-HSA-9024993|Reactome:R-HSA-9020257|MetaCyc:3.3.2.10-RXN|Reactome:R-HSA-9026008|Reactome:R-HSA-9018862|RHEA:19037|Reactome:R-HSA-9020253|EC:3.3.2.10|Reactome:R-HSA-9020252|Reactome:R-HSA-9018877|Reactome:R-HSA-9020258|Reactome:R-HSA-9024890|Reactome:R-HSA-9026000|UM-BBD_enzymeID:e0397|Reactome:R-HSA-9024973|Reactome:R-HSA-9020270|Reactome:R-HSA-9025998									molecular_function											owl:Class	
GO:0032498	biolink:NamedThing	detection of muramyl dipeptide	The series of events in which a muramyl dipeptide stimulus is received by a cell and converted into a molecular signal. Muramyl dipeptide is derived from peptidoglycan.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0032495	biolink:NamedThing	response to muramyl dipeptide	Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a muramyl dipeptide stimulus. Muramyl dipeptide is derived from peptidoglycan.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:2000931	biolink:NamedThing	negative regulation of cellobiose metabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of cellobiose metabolic process.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of cellobiose metabolism							tt	2011-08-01T12:42:57Z					biological_process											owl:Class	
GO:0019782	biolink:NamedThing	ISG15 activating enzyme activity	Catalysis of the activation of the small ubiquitin-related modifier ISG15, through the formation of an ATP-dependent high-energy thiolester bond.	tmpzr1t_l9r_go_relaxed.owl	UBE1L													molecular_function											owl:Class	
GO:0008898	biolink:NamedThing	S-adenosylmethionine-homocysteine S-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + L-homocysteine = S-adenosyl-L-homocysteine + L-methionine.	tmpzr1t_l9r_go_relaxed.owl	homocysteine transmethylase activity|S-adenosylmethionine homocysteine transmethylase activity|S-adenosyl-L-methionine:L-homocysteine methyltransferase activity|L-homocysteine S-methyltransferase activity|adenosylmethionine:homocysteine methyltransferase activity|S-adenosyl-L-methionine:L-homocysteine S-methyltransferase activity|S-adenosylmethionine-homocysteine transmethylase activity|S-adenosylmethionine:homocysteine methyltransferase activity|adenosylmethionine transmethylase activity|homocysteine methyltransferase activity				MetaCyc:HOMOCYSTEINE-S-METHYLTRANSFERASE-RXN|RHEA:21820									molecular_function											owl:Class	
GO:0010868	biolink:NamedThing	negative regulation of triglyceride biosynthetic process	Any process that decreases the rate, frequency, or extent of triglyceride biosynthesis. Triglyceride biosynthesis is the collection of chemical reactions and pathways resulting in the formation of triglyceride, any triester of glycerol.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of triacylglycerol biosynthetic process													biological_process											owl:Class	
GO:1903892	biolink:NamedThing	negative regulation of ATF6-mediated unfolded protein response	Any process that stops, prevents or reduces the frequency, rate or extent of the ATF6-mediated unfolded protein response.	tmpzr1t_l9r_go_relaxed.owl	downregulation of ATF6 signaling in response to endoplasmic reticulum stress|inhibition of ATF6-alpha UPR branch|down-regulation of ATF6-alpha UPR branch|negative regulation of ATF6 branch of UPR|downregulation of ATF6-alpha UPR branch|downregulation of UPR signaling by ATF6 stress sensor|down regulation of activating transcription factor 6 signaling in unfolded protein response|negative regulation of ATF6 signaling in response to endoplasmic reticulum stress|down regulation of ATF6-mediated unfolded protein response|down-regulation of ATF6-beta UPR branch|down-regulation of ATF6 signaling in response to endoplasmic reticulum stress|negative regulation of ATF6-beta UPR branch|inhibition of UPR signaling by ATF6 stress sensor|down regulation of ATF6-beta UPR branch|inhibition of ATF6 signaling in response to endoplasmic reticulum stress|down-regulation of ATF6-mediated unfolded protein response|downregulation of endoplasmic reticulum unfolded protein response; ATF6 signaling|negative regulation of endoplasmic reticulum unfolded protein response; ATF6 signaling|down regulation of endoplasmic reticulum unfolded protein response; ATF6 signaling|downregulation of ATF6 branch of UPR|downregulation of ATF6-beta UPR branch|down-regulation of ATF6 branch of UPR|inhibition of ATF6-mediated unfolded protein response|down-regulation of endoplasmic reticulum unfolded protein response; ATF6 signaling|down-regulation of UPR signaling by ATF6 stress sensor|negative regulation of activating transcription factor 6 signaling in unfolded protein response|inhibition of ATF6-beta UPR branch|down regulation of UPR signaling by ATF6 stress sensor|down regulation of ATF6-alpha UPR branch|downregulation of activating transcription factor 6 signaling in unfolded protein response|inhibition of ATF6 branch of UPR|downregulation of ATF6-mediated unfolded protein response|down-regulation of activating transcription factor 6 signaling in unfolded protein response|down regulation of ATF6 branch of UPR|inhibition of activating transcription factor 6 signaling in unfolded protein response|inhibition of endoplasmic reticulum unfolded protein response; ATF6 signaling|negative regulation of ATF6-alpha UPR branch|negative regulation of UPR signaling by ATF6 stress sensor|down regulation of ATF6 signaling in response to endoplasmic reticulum stress							bf	2015-02-09T10:17:26Z					biological_process											owl:Class	
GO:0110019	biolink:NamedThing	IRES-dependent translational initiation of circular RNA	The process where translation initiation recruits the 40S ribosomal subunits via an internal ribosome entry segment (IRES) before an AUG codon is encountered in an appropriate sequence context to initiate circular mRNA translation.	tmpzr1t_l9r_go_relaxed.owl	IRES-dependent translational initiation of circRNA							kmv	2017-06-08T15:36:38Z					biological_process											owl:Class	
GO:0110018	biolink:NamedThing	cap-independent translational initiation of circular RNA	The process where translation initiation recruits the 40S ribosomal subunits in a cap and 5' end independent fashion before an AUG codon is encountered in an appropriate sequence context to initiate circRNA translation.	tmpzr1t_l9r_go_relaxed.owl	cap-independent translational initiation of circRNA							kmv	2017-06-08T15:22:35Z					biological_process											owl:Class	
GO:0051290	biolink:NamedThing	protein heterotetramerization	The formation of a protein heterotetramer, a macromolecular structure consisting of four noncovalently associated subunits, of which not all are identical.	tmpzr1t_l9r_go_relaxed.owl	protein heterotetramer formation|protein heterotetramer biosynthesis|protein heterotetramer biosynthetic process|protein heterotetramer assembly													biological_process											owl:Class	
GO:0098600	biolink:NamedThing	selenomethionine gamma-lyase activity	Catalysis of the reaction: L-Selenomethionine + H2O => Methaneselenol + Ammonia + 2-oxobutanoic acid.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-2408537			dos	2014-04-15T15:00:28Z					molecular_function											owl:Class	
GO:0098891	biolink:NamedThing	extrinsic component of presynaptic active zone membrane	The component of the presynaptic active zone membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0047703	biolink:NamedThing	beta-nitroacrylate reductase activity	Catalysis of the reaction: 3-nitropropanoate + NADP(+) = 3-nitroacrylate + H(+) + NADPH.	tmpzr1t_l9r_go_relaxed.owl	3-nitropropanoate:NADP+ oxidoreductase activity|b-nitroacrylate reductase activity				EC:1.3.1.16|RHEA:23892|MetaCyc:BETA-NITROACRYLATE-REDUCTASE-RXN|KEGG_REACTION:R03900									molecular_function											owl:Class	
GO:0010316	biolink:NamedThing	pyrophosphate-dependent phosphofructokinase complex	Heterodimeric complex that catalyzes the pyrophosphate-dependent phosphorylation of D-fructose 6-phosphate into D-fructose 1,6-bisphosphate.	tmpzr1t_l9r_go_relaxed.owl	PFK complex													cellular_component											owl:Class	
GO:0032398	biolink:NamedThing	MHC class Ib protein complex	A transmembrane protein complex composed of a MHC class Ib alpha chain and, in most cases, an invariant beta2-microglobin chain, and with or without a bound peptide or lipid antigen. Class Ib here refers to non-classical class I molecules, such as those of the CD1 or HLA-E gene families.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0003375	biolink:NamedThing	regulation of dynamin family protein polymerization involved in membrane fission	Any process that modulates the rate, frequency, or extent of dynamin family protein polymerization involved in mitochondrial fission.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-12-09T05:50:15Z					biological_process											owl:Class	
GO:0034420	biolink:NamedThing	co-translational protein acetylation	The addition of an acetyl group to one or more amino acids in a protein, occurring before the protein has been completely translated and released from the ribosome.	tmpzr1t_l9r_go_relaxed.owl	cotranslational protein amino acid acetylation|co-translational protein amino acid acetylation													biological_process											owl:Class	
GO:1901769	biolink:NamedThing	carbapenem biosynthetic process	The chemical reactions and pathways resulting in the formation of carbapenem.	tmpzr1t_l9r_go_relaxed.owl	carbapenem biosynthesis|carbapenem anabolism|carbapenem synthesis|carbapenem formation							yaf	2013-01-15T10:09:06Z					biological_process											owl:Class	
GO:0051937	biolink:NamedThing	catecholamine transport	The directed movement of catecholamines, a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1905892	biolink:NamedThing	negative regulation of cellular response to thapsigargin	Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to thapsigargin.	tmpzr1t_l9r_go_relaxed.owl	inhibition of cellular response to thapsigargin|downregulation of cellular response to thapsigargin|down regulation of cellular response to thapsigargin|down-regulation of cellular response to thapsigargin							bc	2017-02-01T11:36:15Z					biological_process											owl:Class	
GO:1905117	biolink:NamedThing	regulation of ribonucleoside-diphosphate reductase activity	Any process that modulates the frequency, rate or extent of ribonucleoside-diphosphate reductase activity.	tmpzr1t_l9r_go_relaxed.owl	regulation of purine/pyrimidine nucleoside diphosphate reduction|regulation of class I ribonucleotide reductase activity|regulation of adenosylcobalamin-dependent ribonucleotide reductase activity|regulation of aerobic non-heme iron-dependent ribonucleotide reductase activity|regulation of class II ribonucleotide reductase activity|regulation of ribonucleotide reductase activity|regulation of ribonucleoside 5'-diphosphate reductase activity|regulation of class II ribonucleoside-diphosphate reductase activity|regulation of ribonucleotide diphosphate reductase activity|regulation of RNR|regulation of nucleoside diphosphate reductase activity|regulation of class III ribonucleotide reductase activity|regulation of anaerobic iron-sulfur-dependent ribonucleotide reductase activity					An example of this is DRE2 in Saccharomyces cerevisiae (UniProt ID P36152) in PMID:24733891 (inferred from mutant phenotype).		bhm	2016-04-08T08:06:17Z					biological_process											owl:Class	
GO:0010945	biolink:NamedThing	CoA pyrophosphatase activity	Catalysis of the reaction: coenzyme A or its derivatives + H2O = 3',5'-ADP + 4'-phosphopantetheine.	tmpzr1t_l9r_go_relaxed.owl	conezyme A pyrophosphatase activity				Reactome:R-HSA-6809354|Reactome:R-HSA-6810474			tb	2009-04-22T02:06:40Z					molecular_function											owl:Class	
GO:0090439	biolink:NamedThing	tetraketide alpha-pyrone synthase activity	Catalyzes the reaction: a hydroxyacyl-CoA + 3 malonyl-CoA + 2 H+ = a hydroxylated tetraketide alpha-pyrone + 3 CO2 + 4 coenzyme A .	tmpzr1t_l9r_go_relaxed.owl								tb	2012-08-09T14:35:06Z					molecular_function											owl:Class	
GO:0102303	biolink:NamedThing	resveratrol 3,5-O-dimethyltransferase activity	Catalysis of the reaction: 2 S-adenosyl-L-methionine  + trans-resveratrol <=> 2 S-adenosyl-L-homocysteine  + pterostilbene + 2 H+.	tmpzr1t_l9r_go_relaxed.owl					RHEA:32103|EC:2.1.1.240|MetaCyc:RXN-12805									molecular_function											owl:Class	
GO:0005427	biolink:NamedThing	proton-dependent oligopeptide secondary active transmembrane transporter activity	Enables the transfer of a oligopeptide from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by proton movement.	tmpzr1t_l9r_go_relaxed.owl	hydrogen/oligopeptide symporter|proton-dependent oligopeptide transporter activity													molecular_function											owl:Class	
GO:0102411	biolink:NamedThing	quercetin-3,4'-O-glucosyltransferase activity	Catalysis of the reaction: quercetin-3-glucoside + UDP-alpha-D-glucose(2-) <=> quercetin 3,4'-O-diglucoside + UDP(3-).	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-13766									molecular_function											owl:Class	
GO:0001981	biolink:NamedThing	baroreceptor detection of arterial stretch	The series of events by which the change in diameter of an artery is detected and converted to a molecular signal.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:2001175	biolink:NamedThing	positive regulation of histone H2B conserved C-terminal lysine ubiquitination	Any process that activates or increases the frequency, rate or extent of histone H2B conserved C-terminal lysine ubiquitination.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of fission yeast H2B K119 ubiquitination|positive regulation of budding yeast H2B K123 ubiquitination|positive regulation of mammalian H2B K120 ubiquitination							se	2011-10-29T06:28:59Z					biological_process											owl:Class	
GO:2001168	biolink:NamedThing	positive regulation of histone H2B ubiquitination	Any process that activates or increases the frequency, rate or extent of histone H2B ubiquitination.	tmpzr1t_l9r_go_relaxed.owl								se	2011-10-25T10:50:01Z					biological_process											owl:Class	
GO:0010971	biolink:NamedThing	positive regulation of G2/M transition of mitotic cell cycle	Any signalling pathway that activates or increases the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to M phase of the mitotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle|positive regulation of mitotic entry							tb	2009-06-01T10:16:34Z			GO:0031662		biological_process											owl:Class	
GO:0110136	biolink:NamedThing	protein-RNA complex remodeling	The acquisition, loss, or modification of macromolecules within a protein-RNA complex, resulting in the alteration of an existing complex.	tmpzr1t_l9r_go_relaxed.owl								kmv	2019-01-22T19:23:17Z					biological_process											owl:Class	
GO:0042399	biolink:NamedThing	ectoine metabolic process	The chemical reactions and pathways involving ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidinecarboxylic acid), a tetrahydropyrimidine commonly synthesized by halophilic bacteria.	tmpzr1t_l9r_go_relaxed.owl	ectoine metabolism													biological_process											owl:Class	
GO:0034479	biolink:NamedThing	phosphatidylglycerol phospholipase C activity	Catalysis of the reaction: a phosphatidylglycerol + H2O = 1,2-diacylglycerol + glycerol 3-phosphate.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1900762	biolink:NamedThing	averantin catabolic process	The chemical reactions and pathways resulting in the breakdown of averantin.	tmpzr1t_l9r_go_relaxed.owl	averantin catabolism|averantin degradation|averantin breakdown							di	2012-06-04T09:14:45Z					biological_process											owl:Class	
GO:0047144	biolink:NamedThing	2-acylglycerol-3-phosphate O-acyltransferase activity	Catalysis of the reaction: 2-acyl-sn-glycerol 3-phosphate + acyl-CoA = L-phosphatidate + CoA.	tmpzr1t_l9r_go_relaxed.owl	2-acylglycerophosphate acyltransferase activity|acyl-CoA:2-acyl-sn-glycerol 3-phosphate O-acyltransferase activity				Reactome:R-HSA-1482635|EC:2.3.1.52|MetaCyc:2-ACYL2.3.1.15-RXN|Reactome:R-HSA-1482546|RHEA:14233|Reactome:R-HSA-1482646|Reactome:R-HSA-1482533|Reactome:R-HSA-1482691|Reactome:R-HSA-1482626									molecular_function											owl:Class	
GO:0047748	biolink:NamedThing	cholestanetetraol 26-dehydrogenase activity	Catalysis of the reaction: 5-beta-cholestane-3-alpha,7-alpha,12-alpha,26-tetraol + NAD+ = 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestan-26-al + NADH.	tmpzr1t_l9r_go_relaxed.owl	TEHC-NAD oxidoreductase activity|5beta-cholestane-3alpha,7alpha,12alpha,26-tetrol dehydrogenase activity|cholestanetetrol 26-dehydrogenase activity|5beta-cholestane-3alpha,7alpha,12alpha,26-tetraol:NAD+ 26-oxidoreductase activity				RHEA:34631|MetaCyc:CHOLESTANETETRAOL-26-DEHYDROGENASE-RXN									molecular_function											owl:Class	
GO:0097075	biolink:NamedThing	interferon regulatory factor 3-interferon regulatory factor 7 complex	An interferon regulatory factor complex that consists of a heterodimer of interferon regulatory factor 3 and interferon regulatory factor 7.	tmpzr1t_l9r_go_relaxed.owl	IRF3:IRF7 complex							pr	2011-06-15T04:33:36Z					cellular_component											owl:Class	
GO:0070072	biolink:NamedThing	vacuolar proton-transporting V-type ATPase complex assembly	The aggregation, arrangement and bonding together of a vacuolar proton-transporting V-type ATPase complex, proton-transporting two-sector ATPase complex that couples ATP hydrolysis to the transport of protons across the vacuolar membrane.	tmpzr1t_l9r_go_relaxed.owl	V-ATPase complex assembly|V-ATPase assembly													biological_process											owl:Class	
GO:0070070	biolink:NamedThing	proton-transporting V-type ATPase complex assembly	The aggregation, arrangement and bonding together of a proton-transporting V-type ATPase complex, proton-transporting two-sector ATPase complex that couples ATP hydrolysis to the transport of protons across a concentration gradient.	tmpzr1t_l9r_go_relaxed.owl	V-ATPase complex assembly|V-ATPase assembly													biological_process											owl:Class	
GO:0062071	biolink:NamedThing	Pi Mi complex	A transcription factor complex composed of a homeodomain protein and the M-specific peptide Mi that acts at the regulatory region of genes required for the activation of meiosis.	tmpzr1t_l9r_go_relaxed.owl								dph	2018-09-04T13:40:52Z					cellular_component											owl:Class	
GO:0019556	biolink:NamedThing	histidine catabolic process to glutamate and formamide	The chemical reactions and pathways resulting in the breakdown of histidine into other compounds, including glutamate and formamide.	tmpzr1t_l9r_go_relaxed.owl	histidine degradation to glutamate and formamide|histidine breakdown to glutamate and formamide				MetaCyc:HISDEG-PWY									biological_process											owl:Class	
GO:0018361	biolink:NamedThing	peptidyl-glutamine 2-methylation	The methylation of glutamine to form 2-methyl-L-glutamine.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0273									biological_process											owl:Class	
GO:0018364	biolink:NamedThing	peptidyl-glutamine methylation	The addition of a methyl group to a glutamine residue in a protein.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0047860	biolink:NamedThing	diiodophenylpyruvate reductase activity	Catalysis of the reaction: 3-(3,5-diiodo-4-hydroxyphenyl)lactate + NAD(+) = 3-(3,5-diiodo-4-hydroxyphenyl)pyruvate + H(+) + NADH.	tmpzr1t_l9r_go_relaxed.owl	KAR|2-oxo acid reductase activity|aromatic alpha-keto acid|3-(3,5-diiodo-4-hydroxyphenyl)lactate:NAD+ oxidoreductase activity				MetaCyc:DIIODOPHENYLPYRUVATE-REDUCTASE-RXN|EC:1.1.1.96|KEGG_REACTION:R03431|RHEA:20293									molecular_function											owl:Class	
GO:0046074	biolink:NamedThing	dTMP catabolic process	The chemical reactions and pathways resulting in the breakdown of dTMP, deoxyribosylthymine monophosphate.	tmpzr1t_l9r_go_relaxed.owl	dTMP breakdown|dTMP degradation|dTMP catabolism													biological_process											owl:Class	
GO:0019472	biolink:NamedThing	4-hydroxyproline biosynthetic process	The chemical reactions and pathways resulting in the formation of 4-hydroxyproline, C5H9NO3, a derivative of the amino acid proline.	tmpzr1t_l9r_go_relaxed.owl	4-hydroxyproline biosynthesis|4-hydroxyproline synthesis|4-hydroxyproline formation|4-hydroxyproline anabolism													biological_process											owl:Class	
GO:0005749	biolink:NamedThing	mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)	A protein complex located in the mitochondrial inner membrane that forms part of the mitochondrial respiratory chain. Contains the four polypeptide subunits of succinate dehydrogenase, flavin-adenine dinucleotide and iron-sulfur. Catalyzes the oxidation of succinate by ubiquinone. Connects the TCA cycle with the respiratory chain.	tmpzr1t_l9r_go_relaxed.owl	mitochondrial fumarate reductase complex											GO:0009362|GO:0019738|GO:0008136|GO:0030390		cellular_component											owl:Class	
GO:1901267	biolink:NamedThing	cephalosporin C catabolic process	The chemical reactions and pathways resulting in the breakdown of cephalosporin C.	tmpzr1t_l9r_go_relaxed.owl	cephalosporin C catabolism|cephalosporin C breakdown|cephalosporin C degradation							yaf	2012-08-17T14:26:19Z					biological_process											owl:Class	
GO:0046288	biolink:NamedThing	isoflavonoid catabolic process	The chemical reactions and pathways resulting in the breakdown of isoflavonoids, a group of water-soluble phenolic derivatives, isomeric with flavonoids.	tmpzr1t_l9r_go_relaxed.owl	isoflavonoid breakdown|isoflavonoid degradation|isoflavonoid catabolism													biological_process											owl:Class	
GO:0061710	biolink:NamedThing	L-threonylcarbamoyladenylate synthase	Catalysis of the reaction:  L-threonine + ATP + bicarbonate = L-threonylcarbamoyladenylate + diphosphate + H(2)O.	tmpzr1t_l9r_go_relaxed.owl					EC:2.7.7.87|MetaCyc:RXN-14569|RHEA:36407			dph	2015-06-23T08:25:14Z					molecular_function											owl:Class	
GO:1990452	biolink:NamedThing	Parkin-FBXW7-Cul1 ubiquitin ligase complex	A ubiquitin ligase complex containing Parkin (PARK2), the F-box protein FBXW7 (also called SEL-10) and a cullin from the Cul1 subfamily; substrate specificity is conferred by the F-box protein.	tmpzr1t_l9r_go_relaxed.owl	Parkin-HSel-10-Cullin-1 complex|Parkin-FBXW7-Cul1 protein complex|Parkin/Cul1/F-box protein complex|PRKN-FBXW7-Cul1 complex|Park2-FBXW7-Cul1 complex							bf	2014-08-07T14:25:49Z					cellular_component											owl:Class	
GO:0140347	biolink:NamedThing	N-retinylidene-phosphatidylethanolamine flippase activity	Catalysis of the movement of N-retinylidene-N-retinylphosphatidylethanolamine from the exoplasmic to the cytosolic leaftlet of a membrane, using energy from the hydrolysis of ATP.	tmpzr1t_l9r_go_relaxed.owl	N-retinylidene-phosphatidylethanolamine flippase activity (exoplasmic to cytosolic leaftlet)							pg	2019-05-16T13:44:51Z					molecular_function											owl:Class	
GO:0003045	biolink:NamedThing	regulation of systemic arterial blood pressure by physical factors	The regulation of blood pressure mediated by detection of forces within the circulatory system.	tmpzr1t_l9r_go_relaxed.owl	blood pressure regulation by physical factors													biological_process											owl:Class	
GO:0003073	biolink:NamedThing	regulation of systemic arterial blood pressure	The process that modulates the force with which blood travels through the systemic arterial circulatory system. The process is controlled by a balance of processes that increase pressure and decrease pressure.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0018365	biolink:NamedThing	protein-serine epimerase activity	Catalysis of the reaction: (protein)-L-serine = (protein)-D-serine.	tmpzr1t_l9r_go_relaxed.owl	protein-serine racemase activity				MetaCyc:5.1.1.16-RXN|RHEA:10660|EC:5.1.1.16									molecular_function											owl:Class	
GO:0045347	biolink:NamedThing	negative regulation of MHC class II biosynthetic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of MHC class II.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of MHC class II anabolism|negative regulation of MHC class II synthesis|down regulation of MHC class II biosynthetic process|negative regulation of MHC class II formation|downregulation of MHC class II biosynthetic process|negative regulation of MHC class II biosynthesis|negative regulation of major histocompatibility complex class II biosynthetic process|down-regulation of MHC class II biosynthetic process|negative regulation of major histocompatibility complex class II biosynthesis|inhibition of MHC class II biosynthetic process													biological_process											owl:Class	
GO:0006697	biolink:NamedThing	ecdysone biosynthetic process	The chemical reactions and pathways resulting in the formation of ecdysone, (22R)-2-beta,3-beta,14,22,25-pentahydroxycholest-7-en-6-one, an ecdysteroid found in insects.	tmpzr1t_l9r_go_relaxed.owl	ecdysone formation|ecdysone synthesis|ecdysone biosynthesis|ecdysone anabolism													biological_process											owl:Class	
GO:0061493	biolink:NamedThing	central plaque of mitotic spindle pole body	One of three laminate structures that form the mitotic spindle pole body; the inner plaque is on the nuclear face of the spindle pole body.	tmpzr1t_l9r_go_relaxed.owl								dph	2012-12-11T09:08:26Z					cellular_component											owl:Class	
GO:0005823	biolink:NamedThing	central plaque of spindle pole body	One of three laminate structures that form the spindle pole body; the central plaque is embedded in the nuclear envelope.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0070814	biolink:NamedThing	hydrogen sulfide biosynthetic process	The chemical reactions and pathways resulting in the formation of hydrogen sulfide, H2S.	tmpzr1t_l9r_go_relaxed.owl	hydrogen sulfide synthesis|hydrogen sulfide anabolism|hydrogen sulphide biosynthetic process|hydrogen sulfide biosynthesis|hydrogen sulphide biosynthesis|hydrogen sulfide formation							mah	2009-07-09T10:45:02Z					biological_process											owl:Class	
GO:0004612	biolink:NamedThing	phosphoenolpyruvate carboxykinase (ATP) activity	Catalysis of the reaction: ATP + oxaloacetate = ADP + CO(2) + H(+) + phosphoenolpyruvate.	tmpzr1t_l9r_go_relaxed.owl	ATP:oxaloacetate carboxy-lyase (transphosphorylating)|phosphopyruvate carboxykinase|PEPCK (ATP)|phosphopyruvate carboxykinase (adenosine triphosphate)|PEPK|phosphoenolpyruvic carboxykinase|phosphopyruvate carboxylase (ATP)|ATP:oxaloacetate carboxy-lyase (transphosphorylating; phosphoenolpyruvate-forming)|phosphoenolpyruvate carboxylase (ATP)				RHEA:18617|MetaCyc:PEPCARBOXYKIN-RXN|KEGG_REACTION:R00341|EC:4.1.1.49									molecular_function											owl:Class	
GO:0010199	biolink:NamedThing	organ boundary specification between lateral organs and the meristem	The process in which boundaries between lateral organs and the meristem is established and maintained.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0071294	biolink:NamedThing	cellular response to zinc ion	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a zinc ion stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to zinc							mah	2009-12-10T04:17:10Z					biological_process											owl:Class	
GO:0009855	biolink:NamedThing	determination of bilateral symmetry	The establishment of an organism's body plan or part of an organism with respect to a single longitudinal plane. The pattern can either be symmetric, such that the halves are mirror images, or asymmetric where the pattern deviates from this symmetry.	tmpzr1t_l9r_go_relaxed.owl	determination of bilateral asymmetry													biological_process											owl:Class	
GO:0052319	biolink:NamedThing	regulation of phytoalexin biosynthetic process	Any process that modulates the frequency, rate or extent of phytoalexin biosynthesis, the chemical reactions and pathways resulting in the formation of phytoalexins.	tmpzr1t_l9r_go_relaxed.owl	regulation of phytoalexin biosynthesis													biological_process											owl:Class	
GO:0000906	biolink:NamedThing	6,7-dimethyl-8-ribityllumazine synthase activity	Catalysis of the reaction: 3,4-dihydroxy-2-butanone-4-phosphate + 5-amino-6-ribitylamino-2,4(1H,3H)-pyrimidinedione = 6,7-dimethyl-8-ribityllumazine + phosphate.	tmpzr1t_l9r_go_relaxed.owl	lumazine synthase activity				MetaCyc:LUMAZINESYN-RXN|RHEA:26152|EC:2.5.1.78									molecular_function											owl:Class	
GO:0099632	biolink:NamedThing	protein transport within plasma membrane	A process in which protein is transported from one region of the plasma membrane to another.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0009348	biolink:NamedThing	ornithine carbamoyltransferase complex	A homotrimeric protein complex that catalyzes the transfer of a carbamoyl group to ornithine, forming citrulline.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:1901444	biolink:NamedThing	positive regulation of response to furfural	Any process that activates or increases the frequency, rate or extent of response to furfural.	tmpzr1t_l9r_go_relaxed.owl	upregulation of response to furfural|up-regulation of response to furfural|activation of response to furfural|up regulation of response to furfural							tt	2012-10-02T14:10:51Z					biological_process											owl:Class	
GO:1900751	biolink:NamedThing	4-(trimethylammonio)butanoate transport	The directed movement of a 4-(trimethylammonio)butanoate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	Actinine transport|gamma-butyrobetaine transport|butyrobetaine transport|C7H15NO2 transport|deoxycarnitine transport|gamma-Butyrobetain transport|4-(N-trimethylamino)butyrate transport|4-butyrobetaine transport							jl	2012-05-29T02:32:37Z					biological_process											owl:Class	
GO:0002365	biolink:NamedThing	gamma-delta T cell lineage commitment	The process in which a pro-T cell becomes committed to becoming a gamma-delta T cell.	tmpzr1t_l9r_go_relaxed.owl	gamma-delta T-cell lineage commitment|gamma-delta T-lymphocyte lineage commitment|gamma-delta T lymphocyte lineage commitment													biological_process											owl:Class	
GO:0051844	biolink:NamedThing	translocation of peptides or proteins into symbiont	The directed movement of peptides or proteins produced by an organism to a location inside the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	transport of peptides or proteins into symbiont													biological_process											owl:Class	
GO:0051862	biolink:NamedThing	translocation of molecules into symbiont	The directed movement of molecule(s) produced by an organism to a location inside the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	transport of molecules into symbiont													biological_process											owl:Class	
GO:0004494	biolink:NamedThing	methylmalonyl-CoA mutase activity	Catalysis of the reaction: (R)-methylmalonyl-CoA = succinyl-CoA.	tmpzr1t_l9r_go_relaxed.owl	methylmalonyl coenzyme A carbonylmutase activity|(S)-methylmalonyl-CoA mutase activity|methylmalonyl coenzyme A mutase activity|(R)-methylmalonyl-CoA CoA-carbonylmutase activity|(R)-2-methyl-3-oxopropanoyl-CoA CoA-carbonylmutase activity|methylmalonyl-CoA CoA-carbonyl mutase activity				RHEA:22888|EC:5.4.99.2|MetaCyc:METHYLMALONYL-COA-MUT-RXN|Reactome:R-HSA-3322971|Reactome:R-HSA-71010|UM-BBD_reactionID:r0922|KEGG_REACTION:R00833									molecular_function											owl:Class	
GO:0014702	biolink:NamedThing	free sarcoplasmic reticulum membrane	The part of the sarcoplasmic reticulum membrane that contains calcium pumps and is devoted to calcium uptake. The free sarcoplasmic reticulum membrane consists of the longitudinal sarcoplasmic reticulum membrane and the non-junctional region of the terminal cisterna membrane.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0009149	biolink:NamedThing	pyrimidine nucleoside triphosphate catabolic process	The chemical reactions and pathways resulting in the breakdown of pyrimidine nucleoside triphosphate, a compound consisting of a pyrimidine base linked to a ribose or deoxyribose sugar esterified with triphosphate on the sugar.	tmpzr1t_l9r_go_relaxed.owl	pyrimidine nucleoside triphosphate degradation|pyrimidine nucleoside triphosphate breakdown|pyrimidine nucleoside triphosphate catabolism													biological_process											owl:Class	
GO:1900044	biolink:NamedThing	regulation of protein K63-linked ubiquitination	Any process that modulates the frequency, rate or extent of protein K63-linked ubiquitination.	tmpzr1t_l9r_go_relaxed.owl	regulation of protein K63-linked polyubiquitination							bf	2012-01-19T11:44:37Z					biological_process											owl:Class	
GO:0140077	biolink:NamedThing	positive regulation of lipoprotein transport	Any process that activates or increases the rate or extent of lipoprotein transport.	tmpzr1t_l9r_go_relaxed.owl								pg	2017-07-21T15:41:54Z					biological_process											owl:Class	
GO:0097202	biolink:NamedThing	activation of cysteine-type endopeptidase activity	Any process that initiates the activity of the inactive enzyme cysteine-type endopeptidase.	tmpzr1t_l9r_go_relaxed.owl	activation of caspase activity|activation of metacaspase activity					This term should be used to annotate gene products within the context of cellular processes other than apoptotic cell death (e.g., cell cycle arrest). To annotate gene products involved in activation of cysteine-type endopeptidases where the activation results in apoptotic process, please use the more granular term GO:0006919.		pr	2011-12-19T02:44:04Z					biological_process											owl:Class	
GO:1905723	biolink:NamedThing	negative regulation of trypanothione biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of trypanothione biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of trypanothione biosynthesis|down-regulation of trypanothione synthesis|inhibition of trypanothione formation|down regulation of trypanothione anabolism|downregulation of trypanothione formation|negative regulation of trypanothione formation|down-regulation of trypanothione anabolism|inhibition of trypanothione synthesis|down-regulation of trypanothione formation|down-regulation of trypanothione biosynthetic process|inhibition of trypanothione biosynthetic process|negative regulation of trypanothione synthesis|down regulation of trypanothione formation|inhibition of trypanothione biosynthesis|down regulation of trypanothione biosynthetic process|downregulation of trypanothione synthesis|downregulation of trypanothione biosynthesis|inhibition of trypanothione anabolism|negative regulation of trypanothione biosynthesis|downregulation of trypanothione biosynthetic process|downregulation of trypanothione anabolism|negative regulation of trypanothione anabolism|down regulation of trypanothione biosynthesis|down regulation of trypanothione synthesis							rz	2016-11-25T14:44:42Z					biological_process											owl:Class	
GO:0002826	biolink:NamedThing	negative regulation of T-helper 1 type immune response	Any process that stops, prevents, or reduces the frequency, rate, or extent of a T-helper 1 type immune response.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of T-helper 1 type immune response|downregulation of T-helper 1 type immune response|inhibition of T-helper 1 type immune response|down regulation of T-helper 1 type immune response													biological_process											owl:Class	
GO:0061216	biolink:NamedThing	regulation of transcription from RNA polymerase II promoter involved in mesonephros development	Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the mesonephros progressing from its initial formation to the mature state.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-08-17T03:32:27Z					biological_process											owl:Class	
GO:0030641	biolink:NamedThing	regulation of cellular pH	Any process involved in the maintenance of an internal equilibrium of hydrogen ions (protons) within a cell or between a cell and its external environment.	tmpzr1t_l9r_go_relaxed.owl	cellular hydrogen ion homeostasis|proton homeostasis													biological_process											owl:Class	
GO:0140243	biolink:NamedThing	regulation of translation at synapse	Any process that regulates translation occurring at the synapse.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/synapse/issues/210				Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.		pg	2018-07-15T09:38:26Z					biological_process											owl:Class	
GO:0045755	biolink:NamedThing	negative regulation of initiation of acetate catabolic process by acetate	Any process that stops or prevents the activation, by acetate, of the chemical reactions and pathways resulting in the breakdown of acetate.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of initiation of acetate breakdown by acetate|down-regulation of initiation of acetate catabolic process by acetate|inhibition of initiation of acetate catabolic process by acetate|negative regulation of initiation of acetate degradation by acetate|downregulation of initiation of acetate catabolic process by acetate|down regulation of initiation of acetate catabolic process by acetate													biological_process											owl:Class	
GO:0031064	biolink:NamedThing	negative regulation of histone deacetylation	Any process that stops, prevents, or reduces the frequency, rate or extent of the removal of acetyl groups from histones.	tmpzr1t_l9r_go_relaxed.owl	down regulation of histone deacetylation|inhibition of histone deacetylation|downregulation of histone deacetylation|down-regulation of histone deacetylation													biological_process											owl:Class	
GO:1901559	biolink:NamedThing	response to ribavirin	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ribavirin stimulus.	tmpzr1t_l9r_go_relaxed.owl								hp	2012-11-02T09:46:28Z					biological_process											owl:Class	
GO:0010255	biolink:NamedThing	glucose mediated signaling pathway	The process in which a change in the level of mono- and disaccharide glucose trigger the expression of genes controlling metabolic and developmental processes.	tmpzr1t_l9r_go_relaxed.owl	glucose mediated signalling													biological_process											owl:Class	
GO:1901384	biolink:NamedThing	positive regulation of chorionic trophoblast cell proliferation	Any process that activates or increases the frequency, rate or extent of chorionic trophoblast cell proliferation.	tmpzr1t_l9r_go_relaxed.owl	up regulation of chorionic trophoblast cell proliferation|upregulation of chorionic trophoblast cell proliferation|up-regulation of chorionic trophoblast cell proliferation|activation of chorionic trophoblast cell proliferation							vk	2012-10-01T10:04:41Z					biological_process											owl:Class	
GO:0034661	biolink:NamedThing	ncRNA catabolic process	The chemical reactions and pathways resulting in the breakdown of non-coding RNA transcripts (ncRNAs). Includes the breakdown of cryptic unstable transcripts (CUTs).	tmpzr1t_l9r_go_relaxed.owl	ncRNA catabolism|ncRNA degradation|ncRNA breakdown													biological_process											owl:Class	
GO:0047914	biolink:NamedThing	gamma-glutamylhistamine synthase activity	Catalysis of the reaction: histamine + L-glutamate + ATP = N(alpha)-gamma-L-glutamylhistamine + products of ATP breakdown.	tmpzr1t_l9r_go_relaxed.owl	L-glutamate:histamine ligase activity|g-glutamylhistamine synthase activity|gamma-GHA synthetase activity|gamma-glutaminylhistamine synthetase activity				MetaCyc:GAMMA-GLUTAMYLHISTAMINE-SYNTHASE-RXN|RHEA:18881|EC:6.3.2.18									molecular_function											owl:Class	
GO:1903707	biolink:NamedThing	negative regulation of hemopoiesis	Any process that stops, prevents or reduces the frequency, rate or extent of hemopoiesis.	tmpzr1t_l9r_go_relaxed.owl	inhibition of haemopoiesis|downregulation of hematopoiesis|down-regulation of blood cell biosynthesis|downregulation of blood cell formation|down-regulation of hematopoiesis|negative regulation of hematopoiesis|negative regulation of blood cell biosynthesis|inhibition of hematopoiesis|inhibition of hemopoiesis|down regulation of blood cell biosynthesis|down regulation of blood cell formation|downregulation of hemopoiesis|down-regulation of hemopoiesis|inhibition of blood cell formation|down regulation of haemopoiesis|downregulation of blood cell biosynthesis|down-regulation of blood cell formation|down-regulation of haemopoiesis|down regulation of hematopoiesis|negative regulation of haemopoiesis|negative regulation of blood cell formation|downregulation of haemopoiesis|down regulation of hemopoiesis|inhibition of blood cell biosynthesis					An example of this is Atg7 in mouse (UniProt symbol, Q9D906) in PMID:20080761, inferred from mutant phenotype.		pad	2014-12-04T15:34:21Z					biological_process											owl:Class	
GO:0009309	biolink:NamedThing	amine biosynthetic process	The chemical reactions and pathways resulting in the formation of any organic compound that is weakly basic in character and contains an amino or a substituted amino group. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom.	tmpzr1t_l9r_go_relaxed.owl	amine anabolism|amine formation|amine biosynthesis|amine synthesis													biological_process											owl:Class	
GO:0102673	biolink:NamedThing	fatty aldehyde dehydrogenase activity	Catalysis of the reaction: NAD(1-) + H2O + a fatty aldehyde <=> NADH(2-) + 2 H+ + a fatty acid.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-4142									molecular_function											owl:Class	
GO:0036416	biolink:NamedThing	tRNA stabilization	Prevention of degradation of tRNA molecules.	tmpzr1t_l9r_go_relaxed.owl								bf	2013-08-22T15:41:26Z					biological_process											owl:Class	
GO:0010252	biolink:NamedThing	auxin homeostasis	A homeostatic process that maintains an endogenous steady-state concentration of primary auxin, or constant level of auxin in a biological system, by a number of biochemical processes including transport, biosynthesis, catabolism and conjugation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0044209	biolink:NamedThing	AMP salvage	The chemical reactions and pathways resulting in the formation of adenosine monophosphate (AMP) from derivatives of it (either adenine, ADP or adenosine 3',5'-bisphosphate) without de novo synthesis.	tmpzr1t_l9r_go_relaxed.owl	adenosine monophosphate salvage|AMP biosynthetic process via salvage pathway							jl	2009-10-22T02:52:11Z					biological_process											owl:Class	
GO:0099048	biolink:NamedThing	CRISPR-cas system	An adaptive immune response of bacteria that serves to clear host cells of foreign DNA and RNA. It has three distinct stage: acquisition of foreign DNA by integration into CRISPR loci in the host chromosome, CRISPR RNA (crRNA) biogenesis, and target interference. CISPR stands for Clustered Regularly Interspaced Short Palindromic Repeat, which describes the nature of the loci.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0046202	biolink:NamedThing	cyanide biosynthetic process	The chemical reactions and pathways resulting in the formation of cyanide, NC-, the anion of hydrocyanic acid. Cyanide is a potent inhibitor of respiration.	tmpzr1t_l9r_go_relaxed.owl	cyanide biosynthesis|cyanide formation|cyanide synthesis|cyanide anabolism													biological_process											owl:Class	
GO:0050695	biolink:NamedThing	benzoylformate decarboxylase activity	Catalysis of the reaction: benzoylformate = benzaldehyde + CO2.	tmpzr1t_l9r_go_relaxed.owl	benzoylformate carboxy-lyase (benzaldehyde-forming)|phenylglyoxylate decarboxylase activity|benzoylformate carboxy-lyase activity				UM-BBD_reactionID:r1049|RHEA:23368|EC:4.1.1.7|MetaCyc:BENZOYLFORMATE-DECARBOXYLASE-RXN									molecular_function											owl:Class	
GO:0070573	biolink:NamedThing	metallodipeptidase activity	Catalysis of the hydrolysis of a dipeptide by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.	tmpzr1t_l9r_go_relaxed.owl	metalloexodipeptidase activity|metallo-exo-dipeptidase activity				Reactome:R-HSA-2022398|Reactome:R-HSA-2022405|Reactome:R-HSA-2065355			mah	2009-04-15T03:11:29Z					molecular_function											owl:Class	
GO:0008650	biolink:NamedThing	rRNA (uridine-2'-O-)-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing 2'-O-methyluridine.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-6793127									molecular_function											owl:Class	
GO:0016436	biolink:NamedThing	rRNA (uridine) methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing methyluridine.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0000954	biolink:NamedThing	methionine catabolic process to 3-methylthiopropanoate	The chemical reactions and pathways involving the catabolism of amino acids to produce carboxylic acids with one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. When methionine is used as the substrate, 3-methylthiopropanoate is produced. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of carboxylic acids, sometimes collectively referred to as fusel acids. Depending on the redox state of the cells, alcohol derivatives may be produced instead of carboxylic acids.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1990512	biolink:NamedThing	Cry-Per complex	Nuclear transcriptional repressor complex that is capable of negatively regulating CLOCK-BMAL-dependent transactivation of genes in a delayed negative feedback manner which generates circadian rhythms.	tmpzr1t_l9r_go_relaxed.owl						An example of this is Cry1 in mouse (P97784) in PMID:24855952 (inferred from physical interaction).		bhm	2014-10-08T10:53:07Z					cellular_component											owl:Class	
GO:0098508	biolink:NamedThing	endothelial to hematopoietic transition	The generation of hematopoietic stem cells from hemogenic endothelial cells by a process that includes tight-junction dissolution and loss of cell polarity followed by delamination from the endothelium.	tmpzr1t_l9r_go_relaxed.owl								dos	2013-09-24T15:20:39Z					biological_process											owl:Class	
GO:0032910	biolink:NamedThing	regulation of transforming growth factor beta3 production	Any process that modulates the frequency, rate, or extent of production of transforming growth factor-beta3.	tmpzr1t_l9r_go_relaxed.owl	regulation of transforming growth factor-beta3 production|regulation of TGFB3 production|regulation of TGF-B3 production													biological_process											owl:Class	
GO:2000889	biolink:NamedThing	cellodextrin metabolic process	The chemical reactions and pathways involving a cellodextrin.	tmpzr1t_l9r_go_relaxed.owl	cellodextrin metabolism							jl	2011-07-28T01:00:04Z					biological_process											owl:Class	
GO:0044729	biolink:NamedThing	hemi-methylated DNA-binding	Binding to double-stranded hemi-methylated DNA at replication foci (one strand methylated, while the other strand is unmethylated). Methylation of cytosine or adenine in DNA is an important mechanism for establishing stable heritable epigenetic marks.	tmpzr1t_l9r_go_relaxed.owl	double-stranded hemi-methylated DNA binding							jl	2012-10-24T14:58:14Z					molecular_function											owl:Class	
GO:0033846	biolink:NamedThing	adenosyl-fluoride synthase activity	Catalysis of the reaction: S-adenosyl-L-methionine + fluoride = 5'-deoxy-5'-fluoroadenosine + L-methionine.	tmpzr1t_l9r_go_relaxed.owl	S-adenosyl-L-methionine:fluoride adenosyltransferase activity|fluorinase activity				RHEA:16661|EC:2.5.1.63|MetaCyc:2.5.1.63-RXN									molecular_function											owl:Class	
GO:0002131	biolink:NamedThing	wobble position cytosine ribose methylation	The process in which the ribose of cytidine at position 34 in the anticodon of a tRNA is post-transcriptionally methylated at the 2'-O position.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0010910	biolink:NamedThing	positive regulation of heparan sulfate proteoglycan biosynthesis by positive regulation of epimerase activity	Any process that increases the rate, frequency or extent of heparan sulfate proteoglycan biosynthesis by an increase in epimerase activity. This epimerase activity catalyzes the reaction that converts D-glucuronate into its diastereoisomer in heparan sulfate.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0061331	biolink:NamedThing	epithelial cell proliferation involved in Malpighian tubule morphogenesis	The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population and contributing to the shaping of a Malpighian tubule.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-09-28T02:01:02Z					biological_process											owl:Class	
GO:0102209	biolink:NamedThing	trans-permethrin hydrolase activity	Catalysis of the reaction: (-)-trans-permethrin + H2O <=> H+ + (3-phenoxyphenyl)methanol + (1S,3R)-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate.	tmpzr1t_l9r_go_relaxed.owl					EC:3.1.1.88|RHEA:30283|MetaCyc:RXN-12167									molecular_function											owl:Class	
GO:0070172	biolink:NamedThing	positive regulation of tooth mineralization	Any process that activates or increases the frequency, rate or extent of tooth mineralization, the deposition of calcium salts in tooth structures.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0097134	biolink:NamedThing	cyclin E1-CDK2 complex	A protein complex consisting of cyclin E1 and cyclin-dependent kinase 2 (CDK2). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner.	tmpzr1t_l9r_go_relaxed.owl								pr	2011-08-01T01:58:42Z					cellular_component											owl:Class	
GO:0046102	biolink:NamedThing	inosine metabolic process	The chemical reactions and pathways involving inosine, hypoxanthine riboside, a nucleoside found free but not in combination in nucleic acids except in the anticodons of some tRNAs.	tmpzr1t_l9r_go_relaxed.owl	inosine metabolism													biological_process											owl:Class	
GO:0097453	biolink:NamedThing	mesaxon	Portion of the ensheathing process (either myelin or non-myelin) where the enveloping lips of the ensheathing cell come together so that their apposed plasma membranes run parallel to each other, separated by a cleft 12 nm wide.	tmpzr1t_l9r_go_relaxed.owl	mesaxon of Schwann cell				NIF_Subcellular:sao2127666702			pr	2012-12-19T12:59:13Z					cellular_component											owl:Class	
GO:0061836	biolink:NamedThing	intranuclear rod	A macromolecular fiber consisting of actin and cofilin that is formed in the nucleus as a consequence of chemical or mechanical stress conditions.	tmpzr1t_l9r_go_relaxed.owl	intranuclear actin rod													cellular_component											owl:Class	
GO:0043862	biolink:NamedThing	arginine:agmatine antiporter activity	Catalysis of the reaction: arginine(out) + agmatine(in) = arginine(in) + agmatine(out).	tmpzr1t_l9r_go_relaxed.owl	arginine-agmatine exchange transporter activity|arginine/agmatine antiporter activity|arginine-agmatine antiporter activity|AdiC													molecular_function											owl:Class	
GO:0070805	biolink:NamedThing	regulation of phialide development	Any process that modulates the frequency, rate or extent of phialide development, a process that leads to the formation of phialides. Phialides are specialized cells that bud from the ends of metulae on the conidiophore tip.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-07-08T04:45:03Z					biological_process											owl:Class	
GO:0046217	biolink:NamedThing	indole phytoalexin metabolic process	The chemical reactions and pathways involving indole phytoalexins, any indole compound produced by plants as part of their defense response.	tmpzr1t_l9r_go_relaxed.owl	indole phytoalexin metabolism													biological_process											owl:Class	
GO:0035945	biolink:NamedThing	mitochondrial ncRNA surveillance	The set of processes involved in identifying and degrading defective or aberrant non-coding RNA transcripts (ncRNAs) within the mitochondrion.	tmpzr1t_l9r_go_relaxed.owl	mitochondrial non-coding RNA surveillance|mitochondrial aberrant ncRNA catabolic process|mitochondrial ncRNA quality control							bf	2011-07-28T10:34:59Z					biological_process											owl:Class	
GO:0016268	biolink:NamedThing	O-glycan processing, core 2	The stepwise addition of carbohydrate or carbohydrate derivative residues to the initially added O-linked residue (usually GalNAc) to form the core 2 O-glycan structure, GlcNAc-beta-(1->6)[Gal-beta-(1->3)]-GalNAc.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0061445	biolink:NamedThing	endocardial cushion cell fate commitment	The commitment of a cell to an endocardial cushion cell fate and its capacity to differentiate into an endocardial cushion cell.	tmpzr1t_l9r_go_relaxed.owl								dph	2012-03-13T09:11:03Z					biological_process											owl:Class	
GO:0061094	biolink:NamedThing	regulation of turning behavior involved in mating	Any process that modulates the rate, frequency or extent of turning behavior involved in mating. Turning behavior is the sharp ventral turn performed by the male as he approaches either the hermaphrodite head or tail, whilst trying to locate his partner's vulva. Turning occurs via a sharp ventral coil of the male's tail.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-04-26T02:12:24Z					biological_process											owl:Class	
GO:0019108	biolink:NamedThing	aryl-aldehyde dehydrogenase (NAD) activity	Catalysis of the reaction: an aromatic aldehyde + NAD+ + H2O = an aromatic acid + NADH + H+.	tmpzr1t_l9r_go_relaxed.owl	aryl-aldehyde:NAD+ oxidoreductase activity				RHEA:11804|UM-BBD_reactionID:r0394|MetaCyc:ARYL-ALDEHYDE-DEHYDROGENASE-RXN|EC:1.2.1.29									molecular_function											owl:Class	
GO:0097321	biolink:NamedThing	cell growth mode switching, filamentous to budding	The process in which a cell switches from growing as a filament (elongated cells attached end-to-end) to growing as a round budding cell. An example of this is observed in Candida albicans.	tmpzr1t_l9r_go_relaxed.owl								pr	2012-06-05T11:28:06Z					biological_process											owl:Class	
GO:0036091	biolink:NamedThing	positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress	Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is under oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.	tmpzr1t_l9r_go_relaxed.owl								bf	2012-01-10T02:54:43Z					biological_process											owl:Class	
GO:0036390	biolink:NamedThing	pre-replicative complex assembly involved in bacterial-type DNA replication	The aggregation, arrangement and bonding together of a set of components to form the bacterial pre-replicative complex, a protein-DNA complex that forms at the bacterial oriC during the initial step of DNA replication and allows the origin to become competent, or 'licensed', for replication.	tmpzr1t_l9r_go_relaxed.owl	bacterial pre-RC assembly|bacterial pre-replicative complex assembly							bf	2013-06-05T16:45:21Z					biological_process											owl:Class	
GO:0097127	biolink:NamedThing	cyclin B3-CDK2 complex	A protein complex consisting of cyclin B3 and cyclin-dependent kinase 2 (CDK2). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner.	tmpzr1t_l9r_go_relaxed.owl								pr	2011-08-01T01:47:16Z					cellular_component											owl:Class	
GO:1904547	biolink:NamedThing	regulation of cellular response to glucose starvation	Any process that modulates the frequency, rate or extent of cellular response to glucose starvation.	tmpzr1t_l9r_go_relaxed.owl								al	2015-08-12T09:57:52Z					biological_process											owl:Class	
GO:1990473	biolink:NamedThing	ciliary targeting signal binding	Binding to a ciliary targeting sequence, a specific peptide sequence that acts as a signal to localize a membrane protein to the ciliary membrane.	tmpzr1t_l9r_go_relaxed.owl	CTS binding							pr	2014-09-02T08:22:03Z					molecular_function											owl:Class	
GO:0048722	biolink:NamedThing	anterior cibarial plate development	The process whose specific outcome is the progression of the anterior cibarial plate over time, from their formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0046207	biolink:NamedThing	trypanothione catabolic process	The chemical reactions and pathways resulting in the breakdown of trypanothione (N1,N6,-bis(glutathionyl)spermidine), an essential redox intermediate in intracellular thiol redox regulation which also plays a role in protecting against oxidative stress.	tmpzr1t_l9r_go_relaxed.owl	trypanothione breakdown|trypanothione degradation|trypanothione catabolism													biological_process											owl:Class	
GO:0046206	biolink:NamedThing	trypanothione metabolic process	The chemical reactions and pathways involving trypanothione (N1,N6,-bis(glutathionyl)spermidine), an essential redox intermediate in intracellular thiol redox regulation which also plays a role in protecting against oxidative stress.	tmpzr1t_l9r_go_relaxed.owl	trypanothione metabolism													biological_process											owl:Class	
GO:1900443	biolink:NamedThing	regulation of filamentous growth of a population of unicellular organisms in response to biotic stimulus	Any process that modulates the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to biotic stimulus.	tmpzr1t_l9r_go_relaxed.owl								di	2012-04-25T05:56:18Z					biological_process											owl:Class	
GO:1903009	biolink:NamedThing	proteasome complex disassembly	The disaggregation of a proteasome complex into its constituent components.	tmpzr1t_l9r_go_relaxed.owl	26S proteasome disassembly|proteasome degradation|proteasome disassembly							jl	2014-05-13T12:41:59Z					biological_process											owl:Class	
GO:0052855	biolink:NamedThing	ADP-dependent NAD(P)H-hydrate dehydratase activity	Catalysis of the reaction: (6S)-6beta-hydroxy-1,4,5,6-tetrahydronicotinamide adenine dinucleotide + ADP = AMP + 3 H(+) + NADH + phosphate.	tmpzr1t_l9r_go_relaxed.owl	(6S)-beta-6-hydroxy-1,4,5,6-tetrahydronicotinamide-adenine-dinucleotide hydro-lyase(ADP-hydrolysing; NADH-forming)|(6S)-beta-6-hydroxy-1,4,5,6-tetrahydronicotinamide-adenine-dinucleotide hydro-lyase (ADP-hydrolysing)|ADP-dependent H4NAD(P)OH dehydratase activity|ADP-dependent H(4)NAD(P)OH dehydratase activity|reduced nicotinamide adenine dinucleotide hydrate dehydratase activity				EC:4.2.1.136									molecular_function											owl:Class	
GO:0031983	biolink:NamedThing	vesicle lumen	The volume enclosed by the membrane or protein that forms a vesicle.	tmpzr1t_l9r_go_relaxed.owl					NIF_Subcellular:sao797538226									cellular_component											owl:Class	
GO:0106261	biolink:NamedThing	tRNA uridine(34) acetyltransferase activity	Catalysis of the reaction: acetyl-CoA + H2O + S-adenosyl-L-methionine + uridine(34) in tRNA = 5'-deoxyadenosine + carboxymethyluridine(34) in tRNA + CoA + 2 H(+) + L-methionine.	tmpzr1t_l9r_go_relaxed.owl					RHEA:61020			hjd	2020-05-08T15:21:51Z					molecular_function											owl:Class	
GO:0090378	biolink:NamedThing	seed trichome elongation	The process in which a seed trichome irreversibly increases in size in one [spatial] dimension or along one axis, resulting in the morphogenesis of the cell.	tmpzr1t_l9r_go_relaxed.owl						The increase in length of the seed trichome without cell division. Elongation is defined to be from 5 to 20 DPA in Gossypium spp.		tb	2010-09-15T02:20:47Z					biological_process											owl:Class	
GO:1905430	biolink:NamedThing	cellular response to glycine	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glycine stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to glycin|cellular response to aminoacetic acid|cellular response to aminoethanoic acid|cellular response to Gly							sl	2016-09-08T22:09:23Z					biological_process											owl:Class	
GO:1905429	biolink:NamedThing	response to glycine	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glycine stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to Gly|response to glycin|response to aminoacetic acid|response to aminoethanoic acid							sl	2016-09-08T22:09:15Z					biological_process											owl:Class	
GO:0110015	biolink:NamedThing	positive regulation of elastin catabolic process	Any process that activates or increases the frequency, rate or extent of elastin catabolism, the chemical reactions and pathways resulting in the breakdown of elastin.	tmpzr1t_l9r_go_relaxed.owl								kmv	2017-05-10T14:54:12Z					biological_process											owl:Class	
GO:0090431	biolink:NamedThing	alkyl caffeate ester biosynthetic process	The chemical reactions and pathways resulting in the formation of ester derivatives of alkyl caffeate.	tmpzr1t_l9r_go_relaxed.owl	alkyl caffeate ester anabolism|alkyl caffeate ester synthesis|alkyl caffeate ester formation|alkyl caffeate ester biosynthesis							tb	2012-07-25T11:12:09Z					biological_process											owl:Class	
GO:1990705	biolink:NamedThing	cholangiocyte proliferation	The multiplication or reproduction of cholangiocytes, resulting in the expansion of the cholangiocyte population. A cholangiocyte is an epithelial cell that is part of the bile duct. Cholangiocytes contribute to bile secretion via net release of bicarbonate and water.	tmpzr1t_l9r_go_relaxed.owl	hepatoblast proliferation								2015-03-16T23:23:50Z					biological_process											owl:Class	
GO:0031650	biolink:NamedThing	regulation of heat generation	Any process that modulates the rate or extent of heat generation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0102686	biolink:NamedThing	UDP-glucose:trans-zeatin 9-N-glucosyltransferase	Catalysis of the reaction: UDP-alpha-D-glucose(2-) + trans-zeatin <=> H+ + 9-(alpha-D-glucosyl)-trans-zeatin + UDP(3-).	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-4722									molecular_function											owl:Class	
GO:0097594	biolink:NamedThing	ventral disc dorsal microribbon	Trilaminar structure extending perpendicularly into the cytoplasm along the length of ventral disc microtubules in Giardia species (trophozoite stage). Constituents of dorsal microribbons (also called dorsal ribbons or microribbons) include alpha-coiled-helix proteins approximately 29 to 38 kDa in size. These proteins line the edges of the microribbons but are not found in microtubules. Tubulins are not found in microribbons.	tmpzr1t_l9r_go_relaxed.owl	dorsal microribbon|dorsal ribbon|ventral disk dorsal microribbon|microribbon					Due to the asymmetric nature of the Giardia trophozoite, this term is defined spatially as the trophozoite is viewed from the dorsal side, with the two nuclei dorsal to the ventral disc, and the ventral disc toward the anterior.		pr	2014-04-03T11:20:06Z					cellular_component											owl:Class	
GO:0002678	biolink:NamedThing	positive regulation of chronic inflammatory response	Any process that activates or increases the frequency, rate, or extent of a chronic inflammatory response.	tmpzr1t_l9r_go_relaxed.owl	up regulation of chronic inflammatory response|stimulation of chronic inflammatory response|upregulation of chronic inflammatory response|activation of chronic inflammatory response|up-regulation of chronic inflammatory response													biological_process											owl:Class	
GO:0006044	biolink:NamedThing	N-acetylglucosamine metabolic process	The chemical reactions and pathways involving N-acetylglucosamine. The D isomer is a common structural unit of glycoproteins in plants, bacteria and animals; it is often the terminal sugar of an oligosaccharide group of a glycoprotein.	tmpzr1t_l9r_go_relaxed.owl	N-acetylglucosamine metabolism													biological_process											owl:Class	
GO:1904535	biolink:NamedThing	positive regulation of telomeric loop disassembly	Any process that activates or increases the frequency, rate or extent of telomeric loop disassembly.	tmpzr1t_l9r_go_relaxed.owl	upregulation of telomeric loop disassembly|up-regulation of telomeric loop disassembly|activation of T loop disassembly|positive regulation of T loop disassembly|up regulation of T loop disassembly|up-regulation of T loop disassembly|up regulation of telomeric loop disassembly|upregulation of T loop disassembly|activation of telomeric loop disassembly							nc	2015-07-31T17:15:10Z					biological_process											owl:Class	
GO:0060866	biolink:NamedThing	leaf abscission	The controlled shedding of a leaf.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-08-12T06:33:55Z					biological_process											owl:Class	
GO:0047562	biolink:NamedThing	3-hydroxyaspartate aldolase activity	Catalysis of the reaction: (3R)-3-hydroxy-L-aspartate = glycine + glyoxylate.	tmpzr1t_l9r_go_relaxed.owl	erythro-3-hydroxy-Ls-aspartate glyoxylate-lyase (glycine-forming)|erythro-3-hydroxy-L(s)-aspartate glyoxylate-lyase activity|erythro-beta-hydroxyaspartate glycine-lyase activity|erythro-beta-hydroxyaspartate aldolase activity|erythro-3-hydroxy-Ls-aspartate glyoxylate-lyase activity				MetaCyc:3-HYDROXYASPARTATE-ALDOLASE-RXN|RHEA:14377|KEGG_REACTION:R00478|EC:4.1.3.14									molecular_function											owl:Class	
GO:0016629	biolink:NamedThing	12-oxophytodienoate reductase activity	Catalysis of the reaction: 8-[(1R,2R)-3-oxo-2-{(Z)-pent-2-en-1-yl}cyclopentyl]octanoate + NADP(+) = (15Z)-12-oxophyto-10,15-dienoate + H(+) + NADPH.	tmpzr1t_l9r_go_relaxed.owl	12-oxo-phytodienoate reductase activity|12-oxo-phytodienoic acid reductase activity|8-[(1R,2R)-3-oxo-2-{(Z)-pent-2-enyl}cyclopentyl]octanoate:NADP+ 4-oxidoreductase activity				EC:1.3.1.42|MetaCyc:12-OXOPHYTODIENOATE-REDUCTASE-RXN|RHEA:21888|KEGG_REACTION:R03401									molecular_function											owl:Class	
GO:1904101	biolink:NamedThing	response to acadesine	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acadesine stimulus.	tmpzr1t_l9r_go_relaxed.owl								mr	2015-03-30T22:36:26Z					biological_process											owl:Class	
GO:0033624	biolink:NamedThing	negative regulation of integrin activation	Any process that stops, prevents, or reduces the frequency, rate, or extent of integrin activation.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of integrin complex activation													biological_process											owl:Class	
GO:0034912	biolink:NamedThing	phthalate 3,4-cis-dihydrodiol dehydrogenase activity	Catalysis of the reaction: phthalate 3,4-cis-dihydrodiol + NAD+ = 3,4-dihydroxyphthalate + NADH + H+.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r1445|MetaCyc:RXN5F9-56									molecular_function											owl:Class	
GO:0046785	biolink:NamedThing	microtubule polymerization	The addition of tubulin heterodimers to one or both ends of a microtubule.	tmpzr1t_l9r_go_relaxed.owl	microtubule assembly|microtubule formation													biological_process											owl:Class	
GO:0060927	biolink:NamedThing	cardiac pacemaker cell fate commitment	The commitment of cells to pacemaker cell fates and their capacity to differentiate into pacemaker cells. Pacemaker cells are specialized cardiomyocytes that are responsible for regulating the timing of heart contractions.	tmpzr1t_l9r_go_relaxed.owl	pacemaker cell fate commitment							dph	2009-09-29T11:54:22Z					biological_process											owl:Class	
GO:0051990	biolink:NamedThing	(R)-2-hydroxyglutarate dehydrogenase activity	Catalysis of the reaction: (R)-2-hydroxyglutarate + acceptor = 2-oxoglutarate + reduced acceptor.	tmpzr1t_l9r_go_relaxed.owl	D-2-hydroxyglutarate dehydrogenase activity				Reactome:R-HSA-880053|RHEA:38295|Reactome:R-HSA-880007|EC:1.1.99.39									molecular_function											owl:Class	
GO:0035606	biolink:NamedThing	peptidyl-cysteine S-trans-nitrosylation	Transfer of a nitric oxide (NO) group from one cysteine residue to another.	tmpzr1t_l9r_go_relaxed.owl	protein-to-protein transnitrosylation|S-transnitrosylation|cysteine to cysteine nitrosylation|cysteine-to-cysteine transnitrosylation							bf	2010-11-16T09:54:46Z					biological_process											owl:Class	
GO:0050993	biolink:NamedThing	dimethylallyl diphosphate metabolic process	The chemical reactions and pathways involving dimethylallyl diphosphate.	tmpzr1t_l9r_go_relaxed.owl	dimethylallyl diphosphate metabolism|dimethylallyl pyrophosphate metabolism|DPP metabolism|dimethylallyl pyrophosphate metabolic process|DPP metabolic process													biological_process											owl:Class	
GO:1901907	biolink:NamedThing	diadenosine pentaphosphate catabolic process	The chemical reactions and pathways resulting in the breakdown of diadenosine pentaphosphate.	tmpzr1t_l9r_go_relaxed.owl	diadenosyl pentaphosphate breakdown|diadenosine pentaphosphate catabolism|diadenosyl pentaphosphate degradation|diadenosyl pentaphosphate catabolic process|diadenosyl pentaphosphate catabolism							al	2013-02-13T13:48:21Z					biological_process											owl:Class	
GO:1903497	biolink:NamedThing	cellular response to 11-deoxycorticosterone	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 11-deoxycorticosterone stimulus.	tmpzr1t_l9r_go_relaxed.owl								mr	2014-09-25T17:01:43Z					biological_process											owl:Class	
GO:1901203	biolink:NamedThing	positive regulation of extracellular matrix assembly	Any process that activates or increases the frequency, rate or extent of extracellular matrix assembly.	tmpzr1t_l9r_go_relaxed.owl	activation of extracellular matrix assembly|up-regulation of extracellular matrix assembly|upregulation of extracellular matrix assembly|up regulation of extracellular matrix assembly							rl	2012-07-27T04:04:32Z					biological_process											owl:Class	
GO:2001291	biolink:NamedThing	codeine metabolic process	The chemical reactions and pathways involving codeine, an alkaloid found in the opium poppy, Papaver somniferum var. album. Codeine has analgesic, anti-tussive and anti-diarrhoeal properties.	tmpzr1t_l9r_go_relaxed.owl	codeine metabolism							pr	2012-02-14T01:10:03Z					biological_process											owl:Class	
GO:0032484	biolink:NamedThing	Ral protein signal transduction	A series of molecular signals within the cell that are mediated by a member of the Ral family of proteins switching to a GTP-bound active state.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0005300	biolink:NamedThing	high-affinity tryptophan transmembrane transporter activity	Catalysis of the high-affinity transfer of L-tryptophan from one side of a membrane to the other. Tryptophan is 2-amino-3-(1H-indol-3-yl)propanoic acid. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.	tmpzr1t_l9r_go_relaxed.owl	high-affinity tryptophan transporter activity													molecular_function											owl:Class	
GO:0103015	biolink:NamedThing	4-amino-4-deoxy-L-arabinose transferase activity	Catalysis of the reaction: (Kdo)2-lipid A + 2 4-amino-4-deoxy-alpha-L-arabinopyranosyl di-trans,poly-cis-undecaprenyl phosphate  = (beta-L-Ara4N)2-(KDO)2-lipid A + 2 ditrans,polycis-undecaprenyl phosphate.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN0-2001|EC:2.4.2.43|RHEA:35371									molecular_function											owl:Class	
GO:0004438	biolink:NamedThing	phosphatidylinositol-3-phosphatase activity	Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 3-phosphate + H2O = 1-phosphatidyl-1D-myo-inositol + phosphate.	tmpzr1t_l9r_go_relaxed.owl	1-phosphatidyl-1D-myo-inositol-3-phosphate 3-phosphohydrolase activity|inositol-1,3-bisphosphate 3-phosphatase activity|inositol 1,3-bisphosphate phosphatase activity|inositol-1,4,-bisphosphate 3-phosphatase activity|phosphatidyl-3-phosphate 3-phosphohydrolase activity|D-myo-inositol-1,3-bisphosphate 3-phosphohydrolase activity|inositol-polyphosphate 3-phosphatase activity				Reactome:R-HSA-1675795|RHEA:12316|Reactome:R-HSA-6809720|Reactome:R-HSA-6809975|Reactome:R-HSA-6809777|Reactome:R-HSA-1676114|EC:3.1.3.64|Reactome:R-HSA-1676141|MetaCyc:PHOSPHATIDYLINOSITOL-3-PHOSPHATASE-RXN|Reactome:R-HSA-1675994|Reactome:R-HSA-6809325	Note that this function includes EC:3.1.3.65.						GO:0016315		molecular_function											owl:Class	
GO:0052744	biolink:NamedThing	phosphatidylinositol monophosphate phosphatase activity	Catalysis of the reaction: phosphatidylinositol monophosphate + H2O = phosphatidylinositol + phosphate.	tmpzr1t_l9r_go_relaxed.owl								ai	2011-09-14T01:36:39Z					molecular_function											owl:Class	
GO:0021951	biolink:NamedThing	chemoattraction involved in precerebellar neuron migration	The creation and reception of signals that guide a precerebellar neuron towards their signals, where this process is involved in tangential migration.	tmpzr1t_l9r_go_relaxed.owl	positive chemotaxis involved in precerebellar neuron migration													biological_process											owl:Class	
GO:0102644	biolink:NamedThing	monocyclic sesterterpenediol synthase activity	Catalysis of the reaction: monocyclic sesterterpenediol <=> all-trans-geranylfarnesol + H2O.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-15756									molecular_function											owl:Class	
GO:1905895	biolink:NamedThing	negative regulation of cellular response to tunicamycin	Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to tunicamycin.	tmpzr1t_l9r_go_relaxed.owl	downregulation of cellular response to tunicamycin|down regulation of cellular response to tunicamycin|inhibition of cellular response to tunicamycin|down-regulation of cellular response to tunicamycin							bc	2017-02-01T11:36:42Z					biological_process											owl:Class	
GO:0072582	biolink:NamedThing	17-beta-hydroxysteroid dehydrogenase (NADP+) activity	Catalysis of the reaction: a 17-beta-hydroxysteroid + NADP+ = a 17-oxosteroid + NADPH + H+.	tmpzr1t_l9r_go_relaxed.owl					RHEA:24616			mah	2011-02-07T01:54:21Z					molecular_function											owl:Class	
GO:0051839	biolink:NamedThing	regulation by host of cytolysis of symbiont cells	Any process in which an organism modulates the frequency, rate or extent of the cytolysis by that organism of cells in its symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0036346	biolink:NamedThing	cellular response to L-cysteine	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-cysteine stimulus. L-cysteine is an optically active form of cysteine having L-configuration.	tmpzr1t_l9r_go_relaxed.owl								bf	2012-09-18T14:21:54Z					biological_process											owl:Class	
GO:1901367	biolink:NamedThing	response to L-cysteine	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-cysteine stimulus.	tmpzr1t_l9r_go_relaxed.owl								bf	2012-09-18T13:49:42Z					biological_process											owl:Class	
GO:0033696	biolink:NamedThing	heterochromatin boundary formation	A process that forms a boundary that limits the spreading of heterochromatin along a chromosome.	tmpzr1t_l9r_go_relaxed.owl	regulation of extent of heterochromatin formation|regulation of heterochromatin spreading|negative regulation of extent of heterochromatin formation|negative regulation of extent of heterochromatin assembly|negative regulation of heterochromatin spreading|maintenance of heterochromatin boundaries|regulation of extent of heterochromatin assembly	https://github.com/geneontology/go-ontology/issues/22028										GO:0031454		biological_process											owl:Class	
GO:1903777	biolink:NamedThing	melibiose binding	Binding to melibiose.	tmpzr1t_l9r_go_relaxed.owl								mr	2015-01-06T21:05:29Z					molecular_function											owl:Class	
GO:0061751	biolink:NamedThing	neutral sphingomyelin phosphodiesterase activity	Catalysis of the reaction: H(2)O + sphingomyelin = ceramide + choline phosphate + H(+) in a neutral environment.	tmpzr1t_l9r_go_relaxed.owl	neutral SMase|neutral sphingomyelinase							dph	2015-11-11T14:48:08Z					molecular_function											owl:Class	
GO:0018078	biolink:NamedThing	peptidyl-thyronine iodination	The iodination of peptidyl-thyronine, formed from tyrosine.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0178|RESID:AA0177									biological_process											owl:Class	
GO:0050243	biolink:NamedThing	pyruvate dehydrogenase (NADP+) activity	Catalysis of the reaction: CoA + NADP(+) + pyruvate = acetyl-CoA + CO(2) + NADPH.	tmpzr1t_l9r_go_relaxed.owl	pyruvate:NADP+ oxidoreductase activity|pyruvate:NADP+ 2-oxidoreductase (CoA-acetylating)|pyruvate:NADP(+) oxidoreductase activity				EC:1.2.1.51|RHEA:17425|MetaCyc:PYRUVATE-DEHYDROGENASE-NADP%2b-RXN|KEGG_REACTION:R00210									molecular_function											owl:Class	
GO:0046373	biolink:NamedThing	L-arabinose metabolic process	The chemical reactions and pathways involving L-arabinose, the D-enantiomer of arabino-pentose. L-arabinose occurs free, e.g. in the heartwood of many conifers, and in the combined state, in both furanose and pyranose forms, as a constituent of various plant hemicelluloses, bacterial polysaccharides etc.	tmpzr1t_l9r_go_relaxed.owl	L-arabinose metabolism													biological_process											owl:Class	
GO:0050532	biolink:NamedThing	2-phosphosulfolactate phosphatase activity	Catalysis of the reaction: (2R)-O-phospho-3-sulfolactate + H(2)O = (R)-3-sulfolactate + phosphate.	tmpzr1t_l9r_go_relaxed.owl	2-phosphosulpholactate phosphatase activity|(R)-2-phospho-3-sulfolactate phosphohydrolase activity|(2R)-phosphosulfolactate phosphohydrolase activity|ComB phosphatase activity				RHEA:23416|MetaCyc:R229-RXN|EC:3.1.3.71|KEGG_REACTION:R05789									molecular_function											owl:Class	
GO:0006788	biolink:NamedThing	heme oxidation	The chemical reactions and pathways resulting in the loss of electrons from one or more atoms in heme.	tmpzr1t_l9r_go_relaxed.owl	haem oxidation													biological_process											owl:Class	
GO:0035040	biolink:NamedThing	sperm nuclear envelope removal	Removal of the sperm nuclear envelope, allowing entry of maternal factors into the sperm nucleus.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:2000262	biolink:NamedThing	positive regulation of blood coagulation, common pathway	Any process that activates or increases the frequency, rate or extent of blood coagulation, common pathway.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-11-23T11:42:48Z					biological_process											owl:Class	
GO:0070398	biolink:NamedThing	wall teichoic acid biosynthetic process	The chemical reactions and pathways resulting in the formation of wall teichoic acid, which is a major component of the cell wall of Gram-positive bacteria and typically consists of a polymer of glycerol-phosphate or ribitol-phosphate to which are attached glycosyl and D-alanyl ester residues and which is covalently linked to peptidoglycan.	tmpzr1t_l9r_go_relaxed.owl	wall teichoic acid biosynthesis|wall teichoic acid synthesis|WTA biosynthetic process|wall teichoic acid anabolism|wall teichoic acid formation													biological_process											owl:Class	
GO:0002134	biolink:NamedThing	UTP binding	Binding to UTP, uridine 5'-triphosphate.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0032557	biolink:NamedThing	pyrimidine ribonucleotide binding	Binding to a pyrimidine ribonucleotide, any compound consisting of a pyrimidine ribonucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose moiety.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0005958	biolink:NamedThing	DNA-dependent protein kinase-DNA ligase 4 complex	A large protein complex which is involved in the repair of DNA double-strand breaks and, in mammals, V(D)J recombination events. It consists of the DNA-dependent protein kinase catalytic subunit (DNA-PKcs), the DNA end-binding heterodimer Ku, the nuclear phosphoprotein XRCC4 or a homolog thereof, and DNA ligase IV.	tmpzr1t_l9r_go_relaxed.owl												GO:0005959		cellular_component											owl:Class	
GO:0044315	biolink:NamedThing	protein secretion by the type VII secretion system	The process in which proteins are transferred into the extracellular milieu or directly into host cells, via the type VII protein secretion system.	tmpzr1t_l9r_go_relaxed.owl								jl	2010-06-02T11:57:05Z					biological_process											owl:Class	
GO:0102968	biolink:NamedThing	10-hydroxygeranial oxidoreductase activity	Catalysis of the reaction: (6E)-8-hydroxygeranial + NADP <=> (6E)-8-oxogeranial + NADPH + H+.	tmpzr1t_l9r_go_relaxed.owl					RHEA:32611|MetaCyc:RXN-9369									molecular_function											owl:Class	
GO:0098870	biolink:NamedThing	action potential propagation	The propagation of an action potential along the plane of an excitable membrane.  Action potentials typically propagate once triggered because the depolarization of adjacent membrane regions due to an action potential crosses the firing threshold.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0006017	biolink:NamedThing	deoxyribose 1,5-bisphosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of deoxyribose 1,5-bisphosphate, the diphosphorylated sugar 1,5-diphospho-2-deoxyribose.	tmpzr1t_l9r_go_relaxed.owl	deoxyribose 1,5-bisphosphate anabolism|deoxyribose 1,5-bisphosphate biosynthesis|deoxyribose 1,5-bisphosphate formation|deoxyribose 1,5-bisphosphate synthesis													biological_process											owl:Class	
GO:0033314	biolink:NamedThing	mitotic DNA replication checkpoint signaling	A signal transduction process that contributes to a mitotic DNA replication checkpoint.	tmpzr1t_l9r_go_relaxed.owl	signal transduction involved in S-M checkpoint|mitotic DNA replication checkpoint|signal transduction involved in mitotic DNA replication checkpoint|mitotic cell cycle DNA replication checkpoint|S-M DNA replication checkpoint|S-phase checkpoint|S-M checkpoint|signal transduction involved in mitotic G2/M transition decatenation checkpoint											GO:0072459|GO:0031574|GO:0072443|GO:0072446		biological_process											owl:Class	
GO:0050241	biolink:NamedThing	pyrroline-2-carboxylate reductase activity	Catalysis of the reaction: L-proline + NAD(P)+ = 1-pyrroline-2-carboxylate + NAD(P)H + H+.	tmpzr1t_l9r_go_relaxed.owl	delta1-pyrroline-2-carboxylate reductase activity|L-proline:NAD(P)+ 2-oxidoreductase activity				MetaCyc:PYRROLINE-2-CARBOXYLATE-REDUCTASE-RXN|EC:1.5.1.1									molecular_function											owl:Class	
GO:0098653	biolink:NamedThing	centromere clustering	The process by which centromeres/kinetochores become localized to clusters.	tmpzr1t_l9r_go_relaxed.owl	kinetochore clustering					As inner kinetochores are an integral part of centromeres, we treat centromere and kinetochore clustering as the same process.		dos	2014-05-23T19:03:37Z			GO:0098587		biological_process											owl:Class	
GO:0006718	biolink:NamedThing	juvenile hormone biosynthetic process	The chemical reactions and pathways resulting in the formation of juvenile hormones, the three sesquiterpenoid derivatives that function to maintain the larval state of insects at molting and that may be required for other processes, e.g. oogenesis.	tmpzr1t_l9r_go_relaxed.owl	juvenile hormone anabolism|juvenile hormone formation|juvenile hormone biosynthesis|juvenile hormone synthesis													biological_process											owl:Class	
GO:0000458	biolink:NamedThing	endonucleolytic cleavage between LSU-rRNA and 5S rRNA of tricistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 5S)	Endonucleolytic cleavage to separate a pre-LSU-rRNA from a pre-5S rRNA originally produced as a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, the Large Subunit (LSU) rRNA, and the 5S rRNA, in that order, from 5' to 3' along the primary transcript. Note that the use of the word tricistronic refers only to the number of mature rRNA molecules which will be produced from the primary transcript and ignores tRNAs that may also be present within the primary transcript.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0060578	biolink:NamedThing	superior vena cava morphogenesis	The process in which the anatomical structure of superior vena cava generated and organized. The superior vena cava is a blood vessel that transports blood from the upper body to the heart.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-05-06T08:47:21Z					biological_process											owl:Class	
GO:0030579	biolink:NamedThing	ubiquitin-dependent SMAD protein catabolic process	The chemical reactions and pathways resulting in the breakdown of SMAD signaling proteins by ubiquitination and targeting to the proteasome.	tmpzr1t_l9r_go_relaxed.owl	ubiquitin-dependent SMAD protein catabolism|ubiquitin-dependent SMAD protein degradation|ubiquitin-dependent SMAD protein breakdown													biological_process											owl:Class	
GO:0030259	biolink:NamedThing	lipid glycosylation	Covalent attachment of a glycosyl residue to a lipid molecule.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0007116	biolink:NamedThing	regulation of cell budding	Any process that modulates the frequency, rate or extent of the formation and growth of cell buds.	tmpzr1t_l9r_go_relaxed.owl	regulation of budding													biological_process											owl:Class	
GO:0005798	biolink:NamedThing	Golgi-associated vesicle	Any vesicle associated with the Golgi complex and involved in mediating transport within the Golgi or between the Golgi and other parts of the cell.	tmpzr1t_l9r_go_relaxed.owl	vesicular component|Golgi vesicle				NIF_Subcellular:sao819927218	Note that this definition includes vesicles that are transiently associated with the Golgi.								cellular_component											owl:Class	
GO:0070506	biolink:NamedThing	high-density lipoprotein particle receptor activity	Combining with a high-density lipoprotein particle and delivering the high-density lipoprotein into the cell via endocytosis.	tmpzr1t_l9r_go_relaxed.owl	high-density lipoprotein receptor activity|HDL receptor													molecular_function											owl:Class	
GO:0014815	biolink:NamedThing	initiation of skeletal muscle satellite cell activation by growth factor signaling, involved in skeletal muscle regeneration	Signalling between growth factors and their receptors that results in the activation of satellite cell, where this process is involved in skeletal muscle regeneration. Satellite cells are quiescent cells that are located between the basal lamina and the plasmalemma of the muscle fiber, which are the main contributors to postnatal muscle growth. In adult muscle, satellite cells become activated to divide and differentiate in response to muscle damage.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0006256	biolink:NamedThing	UDP catabolic process	The chemical reactions and pathways resulting in the breakdown of UDP, uridine (5'-)diphosphate.	tmpzr1t_l9r_go_relaxed.owl	UDP catabolism|UDP degradation|UDP breakdown													biological_process											owl:Class	
GO:0051114	biolink:NamedThing	peptidyl-histidine uridylylation	The uridylylation of peptidyl-histidine to form peptidyl-1'-(phospho-5'-uridine)-L-histidine (otherwise known as tau-UMP-histidine, tele-UMP-histidine) or peptidyl-3'-(phospho-5'-uridine)-L-histidine (otherwise known as pi-UMP-histidine, pros-UMP-histidine).	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0372									biological_process											owl:Class	
GO:0071622	biolink:NamedThing	regulation of granulocyte chemotaxis	Any process that modulates the rate, frequency or extent of granulocyte chemotaxis. Granulocyte chemotaxis is the movement of a granulocyte in response to an external stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-02-09T04:09:24Z					biological_process											owl:Class	
GO:0051901	biolink:NamedThing	positive regulation of mitochondrial depolarization	Any process that activates, maintains or increases the frequency, rate or extent of the change in the membrane potential of the mitochondria from negative to positive.	tmpzr1t_l9r_go_relaxed.owl	upregulation of mitochondrial depolarization|up regulation of mitochondrial depolarization|up-regulation of mitochondrial depolarization|stimulation of mitochondrial depolarization|activation of mitochondrial depolarization													biological_process											owl:Class	
GO:0044591	biolink:NamedThing	response to amylopectin	A process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of amylopectin stimulus.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-04-26T03:20:03Z					biological_process											owl:Class	
GO:0047358	biolink:NamedThing	UDP-glucose-glycoprotein glucose phosphotransferase activity	Catalysis of the reaction: glycoprotein D-mannose + UDP-D-glucose = glycoprotein 6-(D-glucose-1-phospho)-D-mannose + UMP.	tmpzr1t_l9r_go_relaxed.owl	GlcPTase activity|UDPglucose-glycoprotein glucose phosphotransferase activity|UDPglucose:glycoprotein-D-mannose glucosephosphotransferase activity|UDP-glucose:glycoprotein-D-mannose glucosephosphotransferase activity|Glc-phosphotransferase activity|UDP-glucose:glycoprotein glucose-1-phosphotransferase activity|uridine diphosphoglucose-glycoprotein glucose-1-phosphotransferase activity				RHEA:20181|MetaCyc:2.7.8.19-RXN|EC:2.7.8.19									molecular_function											owl:Class	
GO:1901323	biolink:NamedThing	response to erythromycin	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an erythromycin stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2012-08-30T10:09:59Z					biological_process											owl:Class	
GO:0070238	biolink:NamedThing	activated T cell autonomous cell death	A T cell apoptotic process that occurs towards the end of the expansion phase following the initial activation of mature T cells by antigen via the accumulation of pro-apoptotic gene products and decrease in anti-apoptotic gene products.	tmpzr1t_l9r_go_relaxed.owl	activated T cell apoptosis|ACAD|activated T-lymphocyte autonomous cell death|activated cell autonomous cell death|activated T lymphocyte autonomous cell death|activated T-cell autonomous cell death													biological_process											owl:Class	
GO:0080100	biolink:NamedThing	L-glutamine:2-oxoglutarate aminotransferase activity	Catalysis of the reaction: L-glutamine + 2-oxoglutarate = 2-oxoglutaramate + L-glutamate.	tmpzr1t_l9r_go_relaxed.owl	L-glutamine:alpha-ketoglutarate aminotransferase activity				EC:2.6.1.50	This reaction falls within the larger set of reactions associated with EC:2.6.1.50 (See BRENDA: http://www.brenda-enzymes.org/php/result_flat.php4?ecno=2.6.1.50).		dhl	2009-04-23T03:56:16Z					molecular_function											owl:Class	
GO:1902059	biolink:NamedThing	negative regulation of sporocarp development involved in sexual reproduction	Any process that stops, prevents or reduces the frequency, rate or extent of sporocarp development involved in sexual reproduction.	tmpzr1t_l9r_go_relaxed.owl	downregulation of fruiting body development involved in sexual reproduction|downregulation of ascus development|negative regulation of fruiting body formation involved in sexual reproduction|down regulation of sporocarp development involved in sexual reproduction|inhibition of perfect stage fruiting body development|down-regulation of ascus development|down-regulation of fruiting body formation involved in sexual reproduction|downregulation of fruiting body formation involved in sexual reproduction|down regulation of fruiting body development involved in sexual reproduction|inhibition of fruiting body development involved in sexual reproduction|inhibition of fruiting body formation involved in sexual reproduction|downregulation of perfect stage fruiting body development|down regulation of perfect stage fruiting body development|downregulation of sporocarp development involved in sexual reproduction|inhibition of ascus development|down regulation of ascus development|down-regulation of perfect stage fruiting body development|down-regulation of sporocarp development involved in sexual reproduction|negative regulation of ascus development|down-regulation of fruiting body development involved in sexual reproduction|down regulation of fruiting body formation involved in sexual reproduction|negative regulation of perfect stage fruiting body development|inhibition of sporocarp development involved in sexual reproduction|negative regulation of fruiting body development involved in sexual reproduction							di	2013-04-16T04:08:42Z					biological_process											owl:Class	
GO:2000111	biolink:NamedThing	positive regulation of macrophage apoptotic process	Any process that activates or increases the frequency, rate or extent of macrophage apoptotic process.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of activation-induced cell death|positive regulation of AICD|positive regulation of macrophage apoptosis							mah	2010-09-15T01:44:21Z					biological_process											owl:Class	
GO:0003911	biolink:NamedThing	DNA ligase (NAD+) activity	Catalysis of the reaction: NAD+ + deoxyribonucleotide(n) + deoxyribonucleotide(m) = AMP + nicotinamide nucleotide + deoxyribonucleotide(n+m).	tmpzr1t_l9r_go_relaxed.owl	polynucleotide synthetase (nicotinamide adenine dinucleotide)|polydeoxyribonucleotide synthase (NAD)|deoxyribonucleic acid joinase|polydeoxyribonucleotide synthase (NAD+) activity|polynucleotide ligase (NAD(+)) activity|deoxyribonucleic acid ligase|DNA ligase (NAD)|DNA-joining enzyme|deoxyribonucleic ligase|polynucleotide ligase (NAD+) activity|deoxyribonucleic joinase|Polydeoxyribonucleotide synthase (NAD(+)) activity|polynucleotide ligase (nicotinamide adenine dinucleotide)|deoxyribonucleate ligase|polynucleotide ligase|deoxyribonucleic repair enzyme|DNA joinase activity|DNA repair enzyme activity|polynucleotide ligase (NAD)|polynucleotide synthetase activity|deoxyribonucleic-joining enzyme|poly(deoxyribonucleotide):poly(deoxyribonucleotide) ligase (AMP-forming, NMN-forming)				MetaCyc:DNA-LIGASE-NAD+-RXN|EC:6.5.1.2									molecular_function											owl:Class	
GO:0098961	biolink:NamedThing	dendritic transport of ribonucleoprotein complex	The directed movement of a ribonucleoprotein complex along microtubules in nerve cell dendrites.	tmpzr1t_l9r_go_relaxed.owl	dendritic transport of RNP complex													biological_process											owl:Class	
GO:0044178	biolink:NamedThing	host cell Golgi membrane	The lipid bilayer surrounding any of the compartments of the host cell Golgi apparatus.	tmpzr1t_l9r_go_relaxed.owl	host Golgi membrane							jl	2009-09-04T03:16:14Z					cellular_component											owl:Class	
GO:0051694	biolink:NamedThing	pointed-end actin filament capping	The binding of a protein or protein complex to the pointed (or minus) end of an actin filament, thus preventing the addition, exchange or removal of further actin subunits.	tmpzr1t_l9r_go_relaxed.owl	pointed-end F-actin capping activity|minus-end F-actin capping activity|pointed-end actin capping activity|minus-end actin filament capping activity													biological_process											owl:Class	
GO:0051693	biolink:NamedThing	actin filament capping	The binding of a protein or protein complex to the end of an actin filament, thus preventing the addition, exchange or removal of further actin subunits.	tmpzr1t_l9r_go_relaxed.owl	actin capping activity|F-actin capping activity													biological_process											owl:Class	
GO:0043207	biolink:NamedThing	response to external biotic stimulus	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external biotic stimulus, an external stimulus caused by, or produced by living things.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0018811	biolink:NamedThing	cyclohex-1-ene-1-carboxyl-CoA hydratase activity	Catalysis of the reaction: cyclohex-1-ene-1-carboxyl-CoA + H2O = 2-hydroxycyclohexane-1-carboxyl-CoA.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:R266-RXN|UM-BBD_reactionID:r0191									molecular_function											owl:Class	
GO:0032791	biolink:NamedThing	lead ion binding	Binding to lead (Pb) ions.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0005965	biolink:NamedThing	protein farnesyltransferase complex	A protein complex that possesses protein farnesyltransferase activity.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0005828	biolink:NamedThing	kinetochore microtubule	Any of the spindle microtubules that attach to the kinetochores of chromosomes by their plus ends, and maneuver the chromosomes during mitotic or meiotic chromosome segregation.	tmpzr1t_l9r_go_relaxed.owl	pole-to-kinetochore microtubule													cellular_component											owl:Class	
GO:0035070	biolink:NamedThing	salivary gland histolysis	The stage-specific break down of the larval salivary glands during Drosophila metamorphosis, to allow replacement of larval structures by tissues and structures that form the adult fly.	tmpzr1t_l9r_go_relaxed.owl	salivary gland regression													biological_process											owl:Class	
GO:0110090	biolink:NamedThing	positive regulation of hippocampal neuron apoptotic process	Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process in hippocampal neurons.	tmpzr1t_l9r_go_relaxed.owl								kmv	2018-02-13T21:22:18Z					biological_process											owl:Class	
GO:0030117	biolink:NamedThing	membrane coat	Any of several different proteinaceous coats that can associate with membranes. Membrane coats include those formed by clathrin plus an adaptor complex, the COPI and COPII complexes, and possibly others. They are found associated with membranes on many vesicles as well as other membrane features such as pits and perhaps tubules.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0045812	biolink:NamedThing	negative regulation of Wnt signaling pathway, calcium modulating pathway	Any process that stops, prevents, or reduces the frequency, rate or extent of the series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors leads to an increase in intracellular calcium and activation of protein kinase C (PKC).	tmpzr1t_l9r_go_relaxed.owl	negative regulation of Wnt receptor signaling pathway, calcium modulating pathway|down-regulation of frizzled-2 signaling pathway|downregulation of frizzled-2 signaling pathway|negative regulation of Wnt-activated signaling pathway, calcium modulating pathway|inhibition of frizzled-2 signaling pathway|down regulation of frizzled-2 signaling pathway|negative regulation of frizzled-2 signalling pathway|negative regulation of frizzled-2 signaling pathway													biological_process											owl:Class	
GO:0031156	biolink:NamedThing	regulation of sorocarp development	Any process that modulates the frequency, rate or extent of sorocarp development. An example of this process is found in Dictyostelium discoideum.	tmpzr1t_l9r_go_relaxed.owl	regulation of fruiting body formation|regulation of fruiting body development													biological_process											owl:Class	
GO:0050092	biolink:NamedThing	meso-tartrate dehydrogenase activity	Catalysis of the reaction: (2R,3S)-tartrate + NAD(+) = dihydroxyfumarate + H(+) + NADH.	tmpzr1t_l9r_go_relaxed.owl	meso-tartrate:NAD+ oxidoreductase activity				EC:1.3.1.7|RHEA:18553|KEGG_REACTION:R02544|MetaCyc:MESO-TARTRATE-DEHYDROGENASE-RXN									molecular_function											owl:Class	
GO:0000311	biolink:NamedThing	plastid large ribosomal subunit	The larger of the two subunits of a plastid ribosome. Two sites on the ribosomal large subunit are involved in translation: the aminoacyl site (A site) and peptidyl site (P site).	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0001094	biolink:NamedThing	TFIID-class transcription factor complex binding	Binding to a general RNA polymerase II transcription factor belonging to the TFIID complex, one of the factors involved in formation of the preinitiation complex (PIC) by RNA polymerase II.	tmpzr1t_l9r_go_relaxed.owl	TFIID-class transcription factor binding							krc	2010-10-28T02:48:33Z					molecular_function											owl:Class	
GO:0033192	biolink:NamedThing	calmodulin-dependent protein phosphatase activity	Catalysis of the reaction: protein serine/threonine phosphate + H2O = protein serine/threonine + phosphate, dependent on the presence of calcium-bound calmodulin.	tmpzr1t_l9r_go_relaxed.owl	calcineurin activity|calcium/calmodulin-dependent protein phosphatase activity|Ca2+/CaM-dependent protein phosphatase activity|calcium- and calmodulin-dependent protein phosphatase activity				Reactome:R-HSA-4551451|Reactome:R-HSA-2730849									molecular_function											owl:Class	
GO:0004723	biolink:NamedThing	calcium-dependent protein serine/threonine phosphatase activity	Catalysis of the reactions: protein serine phosphate + H2O = protein serine + phosphate; and protein threonine phosphate + H2O = protein threonine + phosphate. These reactions require the presence of calcium ions.	tmpzr1t_l9r_go_relaxed.owl	calcium-dependent protein serine/threonine phosphatase, intrinsic catalyst activity|calcineurin				Reactome:R-HSA-2025882							GO:0008596		molecular_function											owl:Class	
GO:0106144	biolink:NamedThing	fraxetin 5-hydroxylase activity	Catalyzes the reaction fraxetin+ NAD(P)H + 02= sideretin + NAD(P)(+) + H20.	tmpzr1t_l9r_go_relaxed.owl					RHEA:57844|EC:1.14.14.164			hjd	2018-09-07T18:24:41Z					molecular_function											owl:Class	
GO:0099636	biolink:NamedThing	cytoplasmic streaming	The directed flow of cytosol (the liquid component of the cytoplasm) and the organelles it contains.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Cytoplasmic_streaming									biological_process											owl:Class	
GO:0004964	biolink:NamedThing	luteinizing hormone receptor activity	Combining with luteinizing hormone (also called lutropin) to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	LH receptor|LHR|lutropin-choriogonadotropic hormone receptor|lutropin receptor											GO:0004976		molecular_function											owl:Class	
GO:0003336	biolink:NamedThing	corneocyte desquamation	The delamination process that results in the shedding of a corneocyte from the surface of the epidermis.	tmpzr1t_l9r_go_relaxed.owl	epidermal desquamation							dph	2009-11-24T09:11:53Z					biological_process											owl:Class	
GO:0015444	biolink:NamedThing	P-type magnesium transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Mg2+(out) -> ADP + phosphate + Mg2+(in).	tmpzr1t_l9r_go_relaxed.owl	magnesium importing ATPase activity|ATP phosphohydrolase (Mg2+-importing)|Mg(2+)-importing ATPase activity|magnesium transmembrane transporter activity, phosphorylative mechanism|magnesium-translocating P-type ATPase activity|Mg2+-importing ATPase activity				MetaCyc:3.6.3.2-RXN|RHEA:10260|EC:7.2.2.14									molecular_function											owl:Class	
GO:0050097	biolink:NamedThing	methylaspartate mutase activity	Catalysis of the reaction: threo-3-methyl-L-aspartate = L-glutamate.	tmpzr1t_l9r_go_relaxed.owl	methylaspartic acid mutase activity|glutamate isomerase activity|glutamic mutase activity|glutamic isomerase activity|glutamate mutase activity|glutamic acid mutase activity|L-threo-3-methylaspartate carboxy-aminomethylmutase activity|beta-methylaspartate-glutamate mutase activity|b-methylaspartate-glutamate mutase activity|glutamic acid isomerase activity				MetaCyc:METHYLASPARTATE-MUTASE-RXN|RHEA:12857|EC:5.4.99.1|KEGG_REACTION:R00262									molecular_function											owl:Class	
GO:0010549	biolink:NamedThing	regulation of membrane disassembly	Any process that modulates the frequency, rate or extent of membrane disassembly.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0019616	biolink:NamedThing	catechol catabolic process, meta-cleavage	The chemical reactions and pathways resulting in the breakdown of catechol via the meta-cleavage pathway, in which the catechol aromatic ring is broken between a hydroxylated carbon atom and an adjacent unsubstituted carbon atom.	tmpzr1t_l9r_go_relaxed.owl	catechol breakdown, meta-cleavage|catechol degradation, meta-cleavage				MetaCyc:P183-PWY									biological_process											owl:Class	
GO:0019227	biolink:NamedThing	neuronal action potential propagation	The propagation of an action potential along an axon, away from the soma.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1990171	biolink:NamedThing	SCF complex disassembly in response to cadmium stress	The disaggregation of the SCF ubiquitin ligase complex in response to cadmium stress.	tmpzr1t_l9r_go_relaxed.owl								rb	2013-08-15T22:38:06Z					biological_process											owl:Class	
GO:0044569	biolink:NamedThing	[Ni-Fe] hydrogenase complex	A microbial enzyme complex which contains nickel and iron in its active site. In Acetomicrobium flavidum it is an alpha 2 beta 2 tetramer.	tmpzr1t_l9r_go_relaxed.owl	nickel-iron hydrogenase complex|Ni-Fe hydrogenase complex							jl	2012-04-18T01:26:35Z					cellular_component											owl:Class	
GO:2000974	biolink:NamedThing	negative regulation of pro-B cell differentiation	Any process that stops, prevents or reduces the frequency, rate or extent of pro-B cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of pro-B cell development|negative regulation of pro-B lymphocyte differentiation							yaf	2011-08-02T03:05:50Z					biological_process											owl:Class	
GO:0060985	biolink:NamedThing	epicardium-derived cardiac vascular smooth muscle cell fate commitment	The commitment of an epicardial cell to a cardiac vascular smooth muscle cell fate and its capacity to differentiate into a cardiac vascular smooth muscle cell.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-10-06T03:11:11Z					biological_process											owl:Class	
GO:0070796	biolink:NamedThing	regulation of cleistothecium development	Any process that modulates the frequency, rate or extent of cleistothecium development, a process that leads to the formation of a cleistothecium. The cleistothecium is a closed sexual fruiting body that contains ascospores in linear asci, characteristic of some filamentous Ascomycete fungi such as members of the genera Aspergillus and Emericella.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-07-08T03:30:04Z					biological_process											owl:Class	
GO:0047404	biolink:NamedThing	glucuronosyl-disulfoglucosamine glucuronidase activity	Catalysis of the reaction: H2O + 3-D-glucuronosyl-N2-,6-disulfo-beta-D-glucosamine = glucuronate + N2,6-disulfo-D-glucosamine.	tmpzr1t_l9r_go_relaxed.owl	3-D-glucuronsyl-2-N,6-disulfo-beta-D-glucosamine glucuronohydrolase activity|glucuronosyl-disulphoglucosamine glucuronidase activity|3-D-glucuronsyl-N2,6-disulfo-beta-D-glucosamine glucuronohydrolase activity				MetaCyc:3.2.1.56-RXN|RHEA:15073|EC:3.2.1.56									molecular_function											owl:Class	
GO:0005637	biolink:NamedThing	nuclear inner membrane	The inner, i.e. lumen-facing, lipid bilayer of the nuclear envelope.	tmpzr1t_l9r_go_relaxed.owl	nucleus inner membrane|inner nuclear membrane|inner envelope				NIF_Subcellular:sao1612527463									cellular_component											owl:Class	
GO:0102174	biolink:NamedThing	4alpha-formyl,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(241)-en-3beta-ol-4alpha-methyl oxidase activity	Catalysis of the reaction: 4alpha-formyl,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(241)-en-3beta-ol + NADH + O2 <=> 4alpha-carboxy-4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(241)-en-3beta-ol + NAD + H2O.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-11927|RHEA:58864									molecular_function											owl:Class	
GO:0043880	biolink:NamedThing	crotonyl-CoA reductase activity	Catalysis of the reduction of crotonyl-CoA to butyryl-CoA.	tmpzr1t_l9r_go_relaxed.owl	crotonyl-coenzyme A reductase activity|CCR													molecular_function											owl:Class	
GO:0042784	biolink:NamedThing	evasion of host immune response via regulation of host complement system	Any mechanism of active immune avoidance which works by regulating the host complement system, e.g. by possessing complement receptors which mediate attachment to, then infection of, host macrophages, which are eventually destroyed. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	active immune evasion via regulation of host complement system|active immune evasion via modulation of host complement system|active evasion of host immune response via regulation of host complement system|active evasion of immune response of other organism via regulation of complement system of other organism involved in symbiotic interaction											GO:0051811		biological_process											owl:Class	
GO:1901893	biolink:NamedThing	positive regulation of cell septum assembly	Any process that activates or increases the frequency, rate or extent of cell septum assembly.	tmpzr1t_l9r_go_relaxed.owl	up regulation of cell septum assembly|upregulation of cell septum assembly|up-regulation of cell septum assembly|activation of cell septum assembly							tb	2013-02-06T20:14:50Z					biological_process											owl:Class	
GO:1902284	biolink:NamedThing	neuron projection extension involved in neuron projection guidance	Any neuron projection extension that is involved in neuron projection guidance.	tmpzr1t_l9r_go_relaxed.owl	neuron projection extension involved in neuron protrusion guidance|neuron process extension involved in neuron process guidance|neuron process extension involved in neuron protrusion guidance|neuron process extension involved in neuron projection guidance|neuron process extension involved in neuronal cell projection guidance|neuron protrusion extension involved in neuron protrusion guidance|neuron projection extension involved in neuronal cell projection guidance|neurite extension involved in neuron projection guidance|neuronal cell projection extension involved in neuron protrusion guidance|neurite extension involved in neuronal cell projection guidance|neuron projection extension involved in neuron process guidance|neurite extension involved in neuron process guidance|neuron process extension involved in neurite guidance|neuronal cell projection extension involved in neuronal cell projection guidance|neuron projection extension involved in neurite guidance|neuron protrusion extension involved in neuronal cell projection guidance|neuronal cell projection extension involved in neuron process guidance|neurite extension involved in neurite guidance|neuronal cell projection extension involved in neuron projection guidance|neurite extension involved in neuron protrusion guidance|neuron protrusion extension involved in neuron process guidance|neuron protrusion extension involved in neuron projection guidance|neuronal cell projection extension involved in neurite guidance|neuron protrusion extension involved in neurite guidance							pr	2013-07-08T15:55:17Z					biological_process											owl:Class	
GO:0099086	biolink:NamedThing	synaptonemal structure	A proteinaceous scaffold found between homologous chromosomes during meiosis.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0110058	biolink:NamedThing	positive regulation of blood vessel endothelial cell differentiation	Any process that activates or increases the frequency, rate or extent of blood vessel endothelial cell differentiation.	tmpzr1t_l9r_go_relaxed.owl								kmv	2017-10-23T14:38:19Z					biological_process											owl:Class	
GO:0044696	biolink:NamedThing	killing by virus of host cell by post-segregational killing	The process by which a virus causes the death of daughter cells which do not contain its genes after host cell division, by a mechanism of post-segregational killing (PSK). The extrachromosomal viral DNA consist of two genes; the product of the second is long lived and toxic, while the product of the first is short lived and antagonizes the lethal action of the toxin. Daughter cells that do not contain the viral extrachromosomal element are killed by the long lived toxin, while daughter cells that do contain the viral extrachromosomal element are protected by the action of the short lived antitoxin it encodes.	tmpzr1t_l9r_go_relaxed.owl	killing by virus of host cell by toxin-antitoxin system|killing by virus of host cell by PSK					Note that this process occurs after the cell division partitioning event.		jl	2012-08-16T13:58:18Z					biological_process											owl:Class	
GO:0032021	biolink:NamedThing	NELF complex	A complex of five proteins, designated NELF-A, -B, -C, -D, and -E in human, that can physically associate with RNP polymerase II to induce transcriptional pausing.	tmpzr1t_l9r_go_relaxed.owl	negative elongation factor complex													cellular_component											owl:Class	
GO:0008023	biolink:NamedThing	transcription elongation factor complex	Any protein complex that interacts with RNA polymerase II to increase (positive transcription elongation factor) or reduce (negative transcription elongation factor) the rate of transcription elongation.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0098998	biolink:NamedThing	extrinsic component of postsynaptic early endosome membrane	The component of the postsynaptic early endosome membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0000482	biolink:NamedThing	maturation of 5S rRNA from tetracistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	Any process involved in the maturation of a precursor 5S ribosomal RNA (rRNA) molecule into a mature 5S rRNA molecule from the pre-rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, Large Subunit (LSU) the 4.5S rRNA, and the 5S rRNA in that order from 5' to 3' along the primary transcript.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0000481	biolink:NamedThing	maturation of 5S rRNA	Any process involved in the maturation of a precursor 5S ribosomal RNA (rRNA) molecule into a mature 5S rRNA molecule.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0070758	biolink:NamedThing	regulation of interleukin-35-mediated signaling pathway	Any process that modulates the rate, frequency or extent of the series of molecular events generated as a consequence of interleukin-35-mediated binding to a cell surface receptor.	tmpzr1t_l9r_go_relaxed.owl	regulation of IL-35-mediated signaling pathway|regulation of interleukin-35-mediated signalling pathway							mah	2009-06-23T01:58:43Z					biological_process											owl:Class	
GO:1905820	biolink:NamedThing	positive regulation of chromosome separation	Any process that activates or increases the frequency, rate or extent of chromosome separation.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of chromatid release|up regulation of chromosome separation|upregulation of chromosome separation|up regulation of chromatid release|upregulation of chromatid release|positive regulation of rDNA separation|up regulation of rDNA separation|up-regulation of chromosome separation|up-regulation of chromatid release|activation of chromosome separation|activation of chromatid release|activation of rDNA separation|upregulation of rDNA separation|up-regulation of rDNA separation							bhm	2017-01-13T13:55:36Z					biological_process											owl:Class	
GO:0044219	biolink:NamedThing	host cell plasmodesma	A fine cytoplasmic channel, found in all higher plants, that connects the cytoplasm of one host cell to that of an adjacent host cell.	tmpzr1t_l9r_go_relaxed.owl								jl	2009-11-12T02:50:52Z					cellular_component											owl:Class	
GO:0044156	biolink:NamedThing	host cell junction	A plasma membrane part that forms a specialized region of connection between two host cells or between a host cell and the host extracellular matrix. At a host cell junction, anchoring proteins extend through the host plasma membrane to link cytoskeletal proteins in one cell to cytoskeletal proteins in neighboring cells or to proteins in the extracellular matrix.	tmpzr1t_l9r_go_relaxed.owl								jl	2009-08-11T04:04:50Z					cellular_component											owl:Class	
GO:0102467	biolink:NamedThing	scutellarein 7-O-glucuronosyltransferase activity	Catalysis of the reaction: UDP-alpha-D-glucuronate + scutellarein <=> UDP( + scutellarin + H+.	tmpzr1t_l9r_go_relaxed.owl					RHEA:28318|MetaCyc:RXN-14058|EC:2.4.1.253									molecular_function											owl:Class	
GO:1990609	biolink:NamedThing	glutamate-cysteine ligase regulator activity	Binds to and modulates the activity of glutamate-cysteine ligase.	tmpzr1t_l9r_go_relaxed.owl								vw	2015-01-20T12:51:13Z					molecular_function											owl:Class	
GO:1900631	biolink:NamedThing	tridecane metabolic process	The chemical reactions and pathways involving tridecane.	tmpzr1t_l9r_go_relaxed.owl	tridecane metabolism							tt	2012-05-21T06:41:16Z					biological_process											owl:Class	
GO:0007311	biolink:NamedThing	maternal specification of dorsal/ventral axis, oocyte, germ-line encoded	Polarization of the oocyte along the dorsal-ventral axis, by a gene product encoded by cells of the germ line. An example of this is found in Drosophila melanogaster.	tmpzr1t_l9r_go_relaxed.owl	maternal determination of dorsal/ventral axis, oocyte, germ-line encoded|maternal specification of dorsoventral axis, oocyte, germ-line encoded|maternal specification of dorsal-ventral axis, oocyte, germ-line encoded											GO:0048124		biological_process											owl:Class	
GO:0031663	biolink:NamedThing	lipopolysaccharide-mediated signaling pathway	A series of molecular signals initiated by the binding of a lipopolysaccharide (LPS) to a receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription. Lipopolysaccharides are major components of the outer membrane of Gram-negative bacteria, making them prime targets for recognition by the immune system.	tmpzr1t_l9r_go_relaxed.owl	LPS-mediated signaling pathway|lipopolysaccharide-mediated signalling pathway													biological_process											owl:Class	
GO:1905454	biolink:NamedThing	negative regulation of myeloid progenitor cell differentiation	Any process that stops, prevents or reduces the frequency, rate or extent of myeloid progenitor cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	down regulation of myeloid progenitor cell differentiation|inhibition of myeloid progenitor cell differentiation|downregulation of myeloid progenitor cell differentiation|down-regulation of myeloid progenitor cell differentiation							rz	2016-09-16T12:32:26Z					biological_process											owl:Class	
GO:1905742	biolink:NamedThing	Ras guanyl-nucleotide exchange factor complex	A protein complex which is capable of Ras guanyl-nucleotide exchange factor activity.	tmpzr1t_l9r_go_relaxed.owl								rjd	2016-12-06T10:24:29Z					cellular_component											owl:Class	
GO:1900011	biolink:NamedThing	negative regulation of corticotropin-releasing hormone receptor activity	Any process that stops, prevents or reduces the frequency, rate or extent of corticotropin-releasing hormone receptor activity.	tmpzr1t_l9r_go_relaxed.owl	down regulation of CRH receptor activity|down regulation of corticotropin-releasing hormone receptor activity|down regulation of adrenocorticotropin-releasing hormone receptor activity|negative regulation of CRH receptor activity|negative regulation of adrenocorticotropin-releasing hormone receptor activity|negative regulation of corticotropin-releasing factor receptor activity|down regulation of CRF receptor activity|negative regulation of CRF receptor activity|down regulation of corticotropin-releasing factor receptor activity							pr	2012-01-10T02:27:27Z					biological_process											owl:Class	
GO:1904121	biolink:NamedThing	phosphatidylethanolamine transfer activity	Removes phosphatidylethanolamine from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle.	tmpzr1t_l9r_go_relaxed.owl	intermembrane phosphatidylethanolamine transfer activity|phosphatidylethanolamine transporter activity|phosphatidylethanolamine carrier activity							sl	2015-04-07T22:51:34Z					molecular_function											owl:Class	
GO:1904916	biolink:NamedThing	transmembrane L-lysine transport from lysosomal lumen to cytosol	The directed movement of L-lysine from the lysosomal lumen across the lysosomal membrane and into the cytosol.	tmpzr1t_l9r_go_relaxed.owl								kmv	2016-01-21T16:27:41Z					biological_process											owl:Class	
GO:1905764	biolink:NamedThing	regulation of protection from non-homologous end joining at telomere	Any process that modulates the frequency, rate or extent of protection from non-homologous end joining at telomere.	tmpzr1t_l9r_go_relaxed.owl	regulation of protection from NHEJ-mediated telomere fusion							nc	2016-12-20T11:28:21Z					biological_process											owl:Class	
GO:0052323	biolink:NamedThing	negative regulation of phytoalexin biosynthetic process	Any process that stops, prevents, or reduces the frequency, rate or extent of phytoalexin biosynthesis, the chemical reactions and pathways resulting in the formation of phytoalexins.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of phytoalexin biosynthesis|inhibition of phytoalexin biosynthesis|down-regulation of phytoalexin biosynthesis|downregulation of phytoalexin biosynthesis|down regulation of phytoalexin biosynthesis													biological_process											owl:Class	
GO:0019569	biolink:NamedThing	L-arabinose catabolic process to xylulose 5-phosphate	The chemical reactions and pathways resulting in the breakdown of L-arabinose into other compounds, including xylulose 5-phosphate.	tmpzr1t_l9r_go_relaxed.owl	L-arabinose degradation to xylulose 5-phosphate|L-arabinose breakdown to xylulose 5-phosphate				MetaCyc:ARABCAT-PWY									biological_process											owl:Class	
GO:0019572	biolink:NamedThing	L-arabinose catabolic process	The chemical reactions and pathways resulting in the breakdown of L-arabinose, the L-enantiomer of arabino-pentose.	tmpzr1t_l9r_go_relaxed.owl	L-arabinose catabolism|L-arabinose degradation|L-arabinose breakdown													biological_process											owl:Class	
GO:0106113	biolink:NamedThing	positive regulation of mitotic cohesin ssDNA (lagging strand) loading	Any process that activates or increases the frequency, rate or extent of mitotic cohesin ssDNA (lagging strand) loading.	tmpzr1t_l9r_go_relaxed.owl								hjd	2018-04-18T14:46:03Z					biological_process											owl:Class	
GO:0050583	biolink:NamedThing	hydrogen dehydrogenase (NADP+) activity	Catalysis of the reaction: NADP+ + H2 = NADPH + H+.	tmpzr1t_l9r_go_relaxed.owl	NADP-reducing hydrogenase activity|hydrogen:NADP+ oxidoreductase activity|NADP-linked hydrogenase activity				EC:1.12.1.3|MetaCyc:1.12.1.3-RXN|RHEA:18637									molecular_function											owl:Class	
GO:0016971	biolink:NamedThing	flavin-linked sulfhydryl oxidase activity	Catalysis of the formation of disulfide bridges in proteins using FAD as the electron acceptor.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0032149	biolink:NamedThing	response to rhamnose	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a rhamnose stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to L-rhamnose stimulus|response to rhamnose stimulus													biological_process											owl:Class	
GO:0019302	biolink:NamedThing	D-ribose biosynthetic process	The chemical reactions and pathways resulting in the formation of D-ribose, (ribo-pentose).	tmpzr1t_l9r_go_relaxed.owl	D-ribose synthesis|D-ribose formation|D-ribose anabolism|D-ribose biosynthesis													biological_process											owl:Class	
GO:0036368	biolink:NamedThing	cone photoresponse recovery	The processes required for a cone photoreceptor to recover, following light activation, so that it can respond to a subsequent light stimulus. Cone recovery requires the shutoff of active participants in the phototransduction cascade, including the visual pigment and downstream signal transducers.	tmpzr1t_l9r_go_relaxed.owl	cone phototransduction termination|cone response recovery							bf	2012-09-26T14:35:20Z					biological_process											owl:Class	
GO:1901743	biolink:NamedThing	2-deoxystreptamine catabolic process	The chemical reactions and pathways resulting in the breakdown of 2-deoxystreptamine.	tmpzr1t_l9r_go_relaxed.owl	2-deoxystreptamine catabolism|2-deoxystreptamine degradation|2-deoxystreptamine breakdown							yaf	2013-01-14T10:02:01Z					biological_process											owl:Class	
GO:0072704	biolink:NamedThing	response to mercaptoethanol	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mercaptoethanol stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to 2-sulfanylethanol							mah	2012-04-11T03:27:02Z					biological_process											owl:Class	
GO:0050151	biolink:NamedThing	oleate hydratase activity	Catalysis of the reaction: (R)-10-hydroxystearate = H(2)O + oleate.	tmpzr1t_l9r_go_relaxed.owl	(R)-10-hydroxystearate 10-hydro-lyase (oleate-forming)|(R)-10-hydroxystearate 10-hydro-lyase activity				RHEA:21852|MetaCyc:OLEATE-HYDRATASE-RXN|KEGG_REACTION:R02813|EC:4.2.1.53									molecular_function											owl:Class	
GO:1990298	biolink:NamedThing	bub1-bub3 complex	Protein complex that associates with the kinetochores.	tmpzr1t_l9r_go_relaxed.owl								al	2014-02-26T09:23:04Z					cellular_component											owl:Class	
GO:0044329	biolink:NamedThing	canonical Wnt signaling pathway involved in positive regulation of cell-cell adhesion	The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes involved in the positive regulation of cell to cell adhesion.	tmpzr1t_l9r_go_relaxed.owl	canonical Wnt-activated signaling pathway involved in positive regulation of cell-cell adhesion|canonical Wnt receptor signalling pathway involved in positive regulation of cell-cell adhesion|canonical Wnt receptor signaling pathway involved in positive regulation of cell-cell adhesion							jl	2010-08-18T04:16:50Z					biological_process											owl:Class	
GO:0090193	biolink:NamedThing	positive regulation of glomerulus development	Any process that increases the rate, frequency or extent of glomerulus development, the progression of the glomerulus over time from its initial formation until its mature state. The glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-12-18T11:17:13Z					biological_process											owl:Class	
GO:0061662	biolink:NamedThing	ISG15 ligase activity	Catalysis of the transfer of a ISG15 to a substrate protein via the reaction X-ISG15 + S --> X + S-ISG15, where X is either an E2 or E3 enzyme, the X-ISG15 linkage is a thioester bond, and the S-ISG15 linkage is an isopeptide bond between the C-terminal amino acid of ISG15 and the epsilon-amino group of lysine residues in the substrate.	tmpzr1t_l9r_go_relaxed.owl	E3							dph	2014-11-06T13:54:48Z					molecular_function											owl:Class	
GO:0061048	biolink:NamedThing	negative regulation of branching involved in lung morphogenesis	Any process that decreases the rate, frequency, or extent of the process in which a highly ordered sequence of patterning events generates the branched structures of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-02-25T10:51:31Z					biological_process											owl:Class	
GO:0016473	biolink:NamedThing	sodium ion-transporting F-type ATPase complex	A sodium ion-transporting two-sector ATPase complex that catalyzes the phosphorylation of ADP to ATP. The complex comprises a membrane sector (F0) that carries out proton transport and a cytoplasmic compartment sector (F1) that catalyzes ATP synthesis by a rotational mechanism.	tmpzr1t_l9r_go_relaxed.owl	sodium-translocating F-type ATPase complex													cellular_component											owl:Class	
GO:1901811	biolink:NamedThing	beta-carotene catabolic process	The chemical reactions and pathways resulting in the breakdown of beta-carotene.	tmpzr1t_l9r_go_relaxed.owl	beta-carotene degradation|beta-carotene catabolism|beta-carotene breakdown							yaf	2013-01-22T10:30:28Z					biological_process											owl:Class	
GO:0009687	biolink:NamedThing	abscisic acid metabolic process	The chemical reactions and pathways involving abscisic acid, 5-(1-hydroxy-2,6,6,trimethyl-4-oxocyclohex-2-en-1-y1)-3-methylpenta-2,4-dienoic acid.	tmpzr1t_l9r_go_relaxed.owl	abscisic acid metabolism													biological_process											owl:Class	
GO:0005049	biolink:NamedThing	nuclear export signal receptor activity	Combining with a nuclear export signal (NES) on a cargo to be transported, to mediate transport of a the cargo through the nuclear pore, from the nuclear lumen to the cytoplasm. The cargo can be either a RNA or a protein.	tmpzr1t_l9r_go_relaxed.owl	NES receptor|exportin activity|importin-alpha export receptor activity|importin-alpha binding	https://github.com/geneontology/go-ontology/issues/14336										GO:0008262		molecular_function											owl:Class	
GO:0140142	biolink:NamedThing	nucleocytoplasmic carrier activity	Binding to and carrying a cargo between the nucleus and the cytoplasm by moving along with the cargo. The cargo can be either a RNA or a protein.	tmpzr1t_l9r_go_relaxed.owl	pre-miRNA transporter activity|nucleocytoplasmic importin/exportin activity|miRNA transporter activity	https://github.com/geneontology/go-ontology/issues/17399|https://github.com/geneontology/go-ontology/issues/14336						pg	2017-12-06T13:40:40Z			GO:0061717|GO:0090631		molecular_function											owl:Class	
GO:0050686	biolink:NamedThing	negative regulation of mRNA processing	Any process that stops, prevents, or reduces the frequency, rate or extent of mRNA processing.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of mRNA processing|downregulation of mRNA processing|inhibition of mRNA processing|down regulation of mRNA processing													biological_process											owl:Class	
GO:1901011	biolink:NamedThing	(S)-reticuline catabolic process	The chemical reactions and pathways resulting in the breakdown of (S)-reticuline.	tmpzr1t_l9r_go_relaxed.owl	(S)-reticuline breakdown|(S)-reticuline degradation|(S)-reticuline catabolism							yaf	2012-06-15T10:46:45Z					biological_process											owl:Class	
GO:0075254	biolink:NamedThing	negative regulation of uredospore formation	Any process that stops, prevents, or reduces the frequency, rate or extent of uredospore formation, a process in which an asexual, dikaryotic, often rusty-colored spore, is formed in a structure called a uredinium.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of ureidospore formation													biological_process											owl:Class	
GO:0140261	biolink:NamedThing	BCOR complex	A protein-containing complex that monoubiquitinates histone H2A on K119, thus it facilitates the maintenance of the transcriptionally repressive state of some genes, such as BCL6. It consists of the corepressor BCOR or BCORL1, a Polycomb group (PcG) and a SCF ubiquitin ligase subcomplexes. In mammals, the core subunits of the complex include the PcG and PcG-associated proteins NSPC1, RING1, RNF2, and RYBP and the components of the SCF ubiquitin ligase, SKP1, and FBXL10.	tmpzr1t_l9r_go_relaxed.owl	non-canonical PRC1-BCOR complex|PRC1.1 complex|BCL6 corepressor (BCOR) complex|BCOR/BCORL1 complex|non-canonical BCOR-PRC1.1 complex							pg	2018-09-11T09:35:05Z					cellular_component											owl:Class	
GO:0047192	biolink:NamedThing	1-alkylglycerophosphocholine O-acetyltransferase activity	Catalysis of the reaction: 1-alkyl-sn-glycero-3-phosphocholine + acetyl-CoA = 1-alkyl-2-acetyl-sn-glycero-3-phosphocholine + CoA.	tmpzr1t_l9r_go_relaxed.owl	1-alkyl-2-lyso-sn-glycero-3-phosphocholine acetyltransferase activity|lysopaf:acetyl CoA acetyltransferase activity|acetyl-CoA:lyso-PAF acetyltransferase activity|lyso-GPC:acetyl CoA acetyltransferase activity|lyso-platelet-activating factor:acetyl-CoA acetyltransferase activity|1-alkyl-2-lysolecithin acetyltransferase activity|platelet-activating factor-synthesizing enzyme activity|platelet-activating factor acylhydrolase activity|blood platelet-activating factor acetyltransferase activity|acetyl-CoA:1-alkyl-sn-glycero-3-phosphocholine 2-O-acetyltransferase activity|acetyl-CoA:1-alkyl-2-lyso-sn-glycero-3-phosphocholine 2-O-acetyltransferase activity|lyso-platelet activating factor:acetyl-CoA acetyltransferase activity|acyl-CoA:1-alkyl-sn-glycero-3-phosphocholine acyltransferase activity				MetaCyc:2.3.1.67-RXN|RHEA:18461|EC:2.3.1.67									molecular_function											owl:Class	
GO:0020025	biolink:NamedThing	subpellicular microtubule	Singlet microtubule that lie underneath the inner membrane pellicle complex and emanate from the basal ring of the conoid.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0051003	biolink:NamedThing	ligase activity, forming nitrogen-metal bonds, forming coordination complexes	Catalysis of the ligation of two substances via a nitrogen-metal bond, forming a coordination complex.	tmpzr1t_l9r_go_relaxed.owl					EC:6.6.1.-									molecular_function											owl:Class	
GO:0051002	biolink:NamedThing	ligase activity, forming nitrogen-metal bonds	Catalysis of the joining of a metal ion to a molecule via a nitrogen-metal bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.	tmpzr1t_l9r_go_relaxed.owl					EC:6.6.-.-									molecular_function											owl:Class	
GO:1901276	biolink:NamedThing	tartrate catabolic process	The chemical reactions and pathways resulting in the breakdown of tartrate.	tmpzr1t_l9r_go_relaxed.owl	tartrate breakdown|tartrate catabolism|tartrate degradation							yaf	2012-08-17T14:52:40Z					biological_process											owl:Class	
GO:1901275	biolink:NamedThing	tartrate metabolic process	The chemical reactions and pathways involving tartrate.	tmpzr1t_l9r_go_relaxed.owl	tartrate metabolism							yaf	2012-08-17T14:52:19Z					biological_process											owl:Class	
GO:0102340	biolink:NamedThing	3-oxo-behenoyl-CoA reductase activity	Catalysis of the reaction: (R)-3-hydroxybehenoyl-CoA(4-) + NADP(3-) <=> 3-oxodocosanoyl-CoA + NADPH + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-13299|EC:1.1.1.330									molecular_function											owl:Class	
GO:1903867	biolink:NamedThing	extraembryonic membrane development	The process whose specific outcome is the progression of an extraembryonic membrane over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl								cjm	2015-02-05T00:42:16Z					biological_process											owl:Class	
GO:0015917	biolink:NamedThing	aminophospholipid transport	The directed movement of aminophospholipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Aminophospholipids contain phosphoric acid as a mono- or diester and an amino (NH2) group.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0005018	biolink:NamedThing	platelet-derived growth factor alpha-receptor activity	Combining with platelet-derived growth factor isoform PDGF-AA, PDGF-BB or PDGF-AB to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	alphaPDGF receptor activity|PDGF alpha-receptor activity													molecular_function											owl:Class	
GO:0070025	biolink:NamedThing	carbon monoxide binding	Binding to carbon monoxide (CO).	tmpzr1t_l9r_go_relaxed.owl	CO binding													molecular_function											owl:Class	
GO:0099107	biolink:NamedThing	ion channel regulator activity involved in G protein-coupled receptor signaling pathway	Modulation of the activity of an ion channel via direct interaction with it as part of G protein-coupled receptor signaling.	tmpzr1t_l9r_go_relaxed.owl	ion channel regulator activity involved in G-protein coupled receptor signaling pathway													molecular_function											owl:Class	
GO:0009407	biolink:NamedThing	toxin catabolic process	The chemical reactions and pathways resulting in the breakdown of toxin, a poisonous compound (typically a protein) that is produced by cells or organisms and that can cause disease when introduced into the body or tissues of an organism.	tmpzr1t_l9r_go_relaxed.owl	toxin catabolism|toxin degradation|toxin breakdown													biological_process											owl:Class	
GO:0015836	biolink:NamedThing	lipid-linked peptidoglycan transport	The directed movement of lipid-linked peptidoglycans into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	lipid-linked murein transport													biological_process											owl:Class	
GO:0004500	biolink:NamedThing	dopamine beta-monooxygenase activity	Catalysis of the reaction: L-ascorbate + dopamine + O(2) = (R)-noradrenaline + dehydroascorbate + H(2)O.	tmpzr1t_l9r_go_relaxed.owl	dopamine beta-oxidase activity|dopamine b-hydroxylase activity|(3,4-dihydroxyphenethylamine)beta-mono-oxygenase activity|dopamine hydroxylase activity|SDBH (soluble dopamine beta-monooxygenase)|3,4-dihydroxyphenethylamine beta-oxidase activity|dopamine beta-hydroxylase activity|phenylamine beta-hydroxylase activity|oxygenase, dopamine beta-mono-|MDBH (membrane-associated dopamine beta-monooxygenase)|4-(2-aminoethyl)pyrocatechol beta-oxidase activity|dopa beta-hydroxylase activity|dopamine-B-hydroxylase activity|3,4-dihydroxyphenethylamine,ascorbate:oxygen oxidoreductase (beta-hydroxylating)				EC:1.14.17.1|MetaCyc:DOPAMINE-BETA-MONOOXYGENASE-RXN|KEGG_REACTION:R02535|RHEA:19117|Reactome:R-HSA-209891									molecular_function											owl:Class	
GO:1900356	biolink:NamedThing	positive regulation of methanofuran metabolic process	Any process that activates or increases the frequency, rate or extent of methanofuran metabolic process.	tmpzr1t_l9r_go_relaxed.owl	upregulation of methanofuran metabolism|up-regulation of methanofuran metabolic process|up regulation of methanofuran metabolic process|up-regulation of methanofuran metabolism|up regulation of methanofuran metabolism|upregulation of methanofuran metabolic process|positive regulation of methanofuran metabolism|activation of methanofuran metabolism|activation of methanofuran metabolic process							tt	2012-04-06T02:16:01Z					biological_process											owl:Class	
GO:0102624	biolink:NamedThing	scutellarein 7-methyl ether 4'-O-methyltransferase activity	Catalysis of the reaction: scutellarein 7-methyl ether + S-adenosyl-L-methionine  <=> ladanein + S-adenosyl-L-homocysteine  + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-15529									molecular_function											owl:Class	
GO:0019632	biolink:NamedThing	shikimate metabolic process	The chemical reactions and pathways involving shikimate, (3R,4S,5R)--3,4,5-trihydroxycyclohex-1-ene-1-carboxylate, the anion of shikimic acid. It is an important intermediate in the biosynthesis of aromatic amino acids.	tmpzr1t_l9r_go_relaxed.owl	shikimate metabolism													biological_process											owl:Class	
GO:0001887	biolink:NamedThing	selenium compound metabolic process	The chemical reactions and pathways involving compounds that contain selenium, such as selenocysteine.	tmpzr1t_l9r_go_relaxed.owl	selenium compound metabolism|selenium metabolism|selenium metabolic process													biological_process											owl:Class	
GO:0044014	biolink:NamedThing	histone acetyltransferase activity (H2B-K5 specific)	Catalysis of the reaction: acetyl-CoA + histone H2B L-lysine (position 5) = CoA + histone H2B N6-acetyl-L-lysine (position 5).	tmpzr1t_l9r_go_relaxed.owl	histone lysine N-acetyltransferase activity (H2B-K5 specific)													molecular_function											owl:Class	
GO:1990302	biolink:NamedThing	Bre1-Rad6 ubiquitin ligase complex	A ubiquitin ligase complex consisting of Bre1 and Rad6 that mediates monoubiquitination of histone H2B to form H2BK123ub1. H2BK123ub1 gives a specific tag for epigenetic transcriptional activation, elongation by RNA polymerase II, telomeric silencing, and is also a prerequisite for H3K4me and H3K79me formation. It thereby plays a central role in histone code and gene regulation. It also modulates the formation of double-strand breaks during meiosis.	tmpzr1t_l9r_go_relaxed.owl	Bre1-Rad6 complex					This complex has been identified in Saccharomyces cerevisiae (P19812) - see PMID:19531475 (inferred from direct assay).		bhm	2014-02-28T16:50:34Z					cellular_component											owl:Class	
GO:0031751	biolink:NamedThing	D4 dopamine receptor binding	Binding to a D4 dopamine receptor.	tmpzr1t_l9r_go_relaxed.owl	D4 dopamine receptor ligand													molecular_function											owl:Class	
GO:0050170	biolink:NamedThing	peptidyl-glutaminase activity	Catalysis of the reaction: alpha-N-peptidyl-L-glutamine + H2O = alpha-N-peptidyl-L-glutamate + NH3.	tmpzr1t_l9r_go_relaxed.owl	peptidoglutaminase I activity|peptidoglutaminase activity|peptideglutaminase activity|peptidyl-L-glutamine amidohydrolase activity				EC:3.5.1.43|MetaCyc:PEPTIDYL-GLUTAMINASE-RXN|RHEA:10032									molecular_function											owl:Class	
GO:0140425	biolink:NamedThing	galactose import across plasma membrane	The directed movement of galactose from outside of a cell, across the plasma membrane and into the cytosol.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/18788						pg	2020-02-10T08:46:09Z					biological_process											owl:Class	
GO:0036223	biolink:NamedThing	cellular response to adenine starvation	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of adenine.	tmpzr1t_l9r_go_relaxed.owl	cellular response to adenine deprivation							bf	2012-05-09T02:26:52Z					biological_process											owl:Class	
GO:0031676	biolink:NamedThing	plasma membrane-derived thylakoid membrane	The pigmented membrane of a plasma membrane-derived thylakoid.	tmpzr1t_l9r_go_relaxed.owl	plasma membrane thylakoid membrane													cellular_component											owl:Class	
GO:0006679	biolink:NamedThing	glucosylceramide biosynthetic process	The chemical reactions and pathways resulting in the formation of glucosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of glucose by a ceramide group.	tmpzr1t_l9r_go_relaxed.owl	glucosylceramide formation|glucosylceramide synthesis|glucosylceramide biosynthesis|glucosylceramide anabolism													biological_process											owl:Class	
GO:0007614	biolink:NamedThing	short-term memory	The memory process that deals with the storage, retrieval and modification of information received a short time (up to about 30 minutes) ago. This type of memory is typically dependent on direct, transient effects of second messenger activation.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Short-term_memory									biological_process											owl:Class	
GO:0047194	biolink:NamedThing	indoleacetylglucose-inositol O-acyltransferase activity	Catalysis of the reaction: 1-O-(indol-3-ylacetyl)-beta-D-glucose + myo-inositol = 1L-1-O-(indol-3-yl)acetyl-myo-inositol + D-glucose.	tmpzr1t_l9r_go_relaxed.owl	1-O-(indol-3-ylacetyl)-beta-D-glucose:myo-inositol indole-3-ylacetyltransferase activity|1-O-(indol-3-yl)acetyl-beta-D-glucose:myo-inositol (indol-3-yl)acetyltransferase activity|indole-3-acetyl-beta-1-D-glucoside:myo-inositol indoleacetyltransferase activity				EC:2.3.1.72|RHEA:21180|KEGG_REACTION:R04333|MetaCyc:2.3.1.72-RXN									molecular_function											owl:Class	
GO:0102613	biolink:NamedThing	trimethyluric acid monooxygenase activity	Catalysis of the reaction: 1,3,7-trimethyluric acid + O2 + NADH + 3 H+ <=> 1,3,7-trimethyl-5-hydroxyisourate + NAD + H2O.	tmpzr1t_l9r_go_relaxed.owl					RHEA:48992|MetaCyc:RXN-15454									molecular_function											owl:Class	
GO:0021815	biolink:NamedThing	modulation of microtubule cytoskeleton involved in cerebral cortex radial glia guided migration	Rearrangements of the microtubule cytoskeleton that contribute to the movement of cells along radial glial cells as a component of the process of cerebral cortex glial-mediated radial migration.	tmpzr1t_l9r_go_relaxed.owl	modulation of microtubule cytoskeleton involved in cerebral cortex glial-mediated radial migration													biological_process											owl:Class	
GO:0033815	biolink:NamedThing	biphenyl synthase activity	Catalysis of the reaction: 3 malonyl-CoA + benzoyl-CoA = 4 CoA + 3,5-dihydroxybiphenyl + 4 CO2.	tmpzr1t_l9r_go_relaxed.owl	malonyl-CoA:benzoyl-CoA malonyltransferase activity|BIS				RHEA:22292|MetaCyc:2.3.1.177-RXN|EC:2.3.1.177									molecular_function											owl:Class	
GO:0006925	biolink:NamedThing	inflammatory cell apoptotic process	Any apoptotic process in an inflammatory cell, any cell participating in the inflammatory response to a foreign substance e.g. neutrophil, macrophage.	tmpzr1t_l9r_go_relaxed.owl	programmed cell death of inflammatory cells by apoptosis|inflammatory cell programmed cell death by apoptosis|programmed cell death, inflammatory cells|killing of inflammatory cells|apoptosis of inflammatory cells|inflammatory cell apoptosis													biological_process											owl:Class	
GO:0010809	biolink:NamedThing	negative regulation of synaptic vesicle priming	Any process that decreases the frequency, rate or extent of synaptic vesicle priming. Synaptic vesicle priming is the formation of SNARE-containing complexes, bringing synaptic vesicle membrane and plasma membranes into close proximity and thereby facilitating membrane fusion.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0048693	biolink:NamedThing	regulation of collateral sprouting of injured axon	Any process that modulates the frequency, rate or extent of collateral sprouting of an injured axon.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1905471	biolink:NamedThing	regulation of histone H3-K79 dimethylation	Any process that modulates the frequency, rate or extent of histone H3-K79 dimethylation.	tmpzr1t_l9r_go_relaxed.owl	regulation of histone H3 K79 dimethylation|regulation of histone lysine H3 K79 dimethylation							hbye	2016-09-21T15:27:02Z					biological_process											owl:Class	
GO:0032251	biolink:NamedThing	positive regulation of adenosine transport	Any process that activates or increases the frequency, rate or extent of the directed movement of adenosine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	upregulation of adenosine transport|up regulation of adenosine transport|stimulation of adenosine transport|activation of adenosine transport|up-regulation of adenosine transport													biological_process											owl:Class	
GO:0032248	biolink:NamedThing	positive regulation of purine nucleoside transport	Any process that activates or increases the frequency, rate or extent of the directed movement of a purine nucleoside into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	stimulation of purine nucleoside transport|up regulation of purine nucleoside transport|activation of purine nucleoside transport|upregulation of purine nucleoside transport|up-regulation of purine nucleoside transport													biological_process											owl:Class	
GO:0120040	biolink:NamedThing	regulation of macrophage proliferation	Any process that modulates the frequency, rate or extent of macrophage proliferation.	tmpzr1t_l9r_go_relaxed.owl								krc	2017-05-10T20:38:19Z					biological_process											owl:Class	
GO:1990003	biolink:NamedThing	inosine-diphosphatase activity	Catalysis of the reaction: IDP + H2O = IMP + phosphate.	tmpzr1t_l9r_go_relaxed.owl	IDP phosphatase activity|IDPase activity|inosine diphosphatase activity				Reactome:R-HSA-2509816|RHEA:35207|EC:3.6.1.64			jl	2012-12-05T16:46:52Z			GO:0090450		molecular_function											owl:Class	
GO:0071410	biolink:NamedThing	cellular response to cyclopentenone	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cyclopentenone stimulus. Cyclopentenones are oxylipins derived from polyunsaturated fatty acids. They are structurally similar to jasmonic acid, but contain a reactive unsaturated carbonyl structure in the cyclo-ring. Cyclopentenones include phytoprostanes and 12-oxo-phytodienoic acid.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-12-14T03:09:49Z					biological_process											owl:Class	
GO:0042646	biolink:NamedThing	plastid nucleoid	The region of a plastid to which the DNA is confined.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0008859	biolink:NamedThing	exoribonuclease II activity	Catalysis of the reaction: RNA + H2O = 5'-phosphomononucleotides. Cleaves RNA in the 3' to 5' direction.	tmpzr1t_l9r_go_relaxed.owl	ribonuclease II activity|BN ribonuclease activity|RNase II activity|ribonuclease Q|RNase II|5'-exoribonuclease activity|Escherichia coli exo-RNase II				MetaCyc:3.1.13.1-RXN|EC:3.1.13.1									molecular_function											owl:Class	
GO:0016896	biolink:NamedThing	exoribonuclease activity, producing 5'-phosphomonoesters	Catalysis of the hydrolysis of ester linkages within ribonucleic acids by removing nucleotide residues from the 3' or 5' end to yield 5' phosphomonoesters.	tmpzr1t_l9r_go_relaxed.owl	exoribonuclease activity, producing 5' phosphomonoesters				EC:3.1.13.-|Reactome:R-HSA-429860									molecular_function											owl:Class	
GO:0060306	biolink:NamedThing	regulation of membrane repolarization	Any process that modulates the establishment or extent of a membrane potential in the polarizing direction towards the resting potential, usually from positive to negative.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0106249	biolink:NamedThing	Nicalin-NOMO complex	A protein complex regulating Nodal signaling. Subunits are highly conserved in vertebrates and include Nicalin, NOMO and TMEM147.	tmpzr1t_l9r_go_relaxed.owl	Nicalin-TMEM147-NOMO complex							hjd	2020-02-18T17:51:43Z					cellular_component											owl:Class	
GO:0120314	biolink:NamedThing	negative regulation of oocyte karyosome formation	Any process that stops, prevents, or reduces the frequency, rate or extent of oocyte karyosome formation, the chromosome organization process in which meiotic chromosomes in the oocyte nucleus cluster together to form a compact spherical structure called the karyosome.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/21298						krc	2021-04-19T21:39:47Z					biological_process											owl:Class	
GO:0036528	biolink:NamedThing	peptidyl-lysine deglycation	The removal of a sugar or dicarbonyl from a lysine residue of a glycated protein.	tmpzr1t_l9r_go_relaxed.owl	deglycation of N-acetyllysine							bf	2016-08-04T10:37:12Z					biological_process											owl:Class	
GO:0003843	biolink:NamedThing	1,3-beta-D-glucan synthase activity	Catalysis of the reaction: UDP-glucose + [(1->3)-beta-D-glucosyl](n) = UDP + [(1->3)-beta-D-glucosyl](n+1).	tmpzr1t_l9r_go_relaxed.owl	UDP-glucose-1,3-beta-D-glucan glucosyltransferase activity|GS-II|1,3-beta-D-glucan synthetase activity|callose synthetase activity|callose synthase activity|paramylon synthetase|1,3-beta-glucan-uridine diphosphoglucosyltransferase activity|1,3-beta-D-glucan-UDP glucosyltransferase activity|(1,3)-beta-glucan (callose) synthase activity|UDP-glucose:(1,3)beta-glucan synthase activity|UDPglucose:1,3-beta-D-glucan 3-beta-D-glucosyltransferase activity|UDP-glucose-1,3-beta-glucan glucosyltransferase activity|1,3-beta-glucan synthase activity|beta-1,3-glucan synthetase activity|beta-1,3-glucan synthase activity|uridine diphosphoglucose-1,3-beta-glucan glucosyltransferase activity|UDP-glucose-beta-glucan glucosyltransferase activity|UDP-glucose:1,3-beta-D-glucan 3-beta-D-glucosyltransferase activity|UDPglucose-1,3-beta-D-glucan glucosyltransferase activity				MetaCyc:13-BETA-GLUCAN-SYNTHASE-RXN|EC:2.4.1.34|RHEA:21476							GO:0009981		molecular_function											owl:Class	
GO:1903496	biolink:NamedThing	response to 11-deoxycorticosterone	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 11-deoxycorticosterone stimulus.	tmpzr1t_l9r_go_relaxed.owl								mr	2014-09-25T17:01:35Z					biological_process											owl:Class	
GO:0009735	biolink:NamedThing	response to cytokinin	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytokinin stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to cytokinin stimulus													biological_process											owl:Class	
GO:0031707	biolink:NamedThing	endothelin A receptor binding	Binding to an endothelin A receptor.	tmpzr1t_l9r_go_relaxed.owl	endothelin-1 receptor binding|endothelin A receptor ligand													molecular_function											owl:Class	
GO:0010816	biolink:NamedThing	calcitonin catabolic process	The chemical reactions and pathways resulting in the breakdown of the peptide calcitonin.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0050515	biolink:NamedThing	4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase activity	Catalysis of the reaction: 4-CDP-2-C-methyl-D-erythritol + ATP = 4-CDP-2-C-methyl-D-erythritol 2-phosphate + ADP + 2 H(+).	tmpzr1t_l9r_go_relaxed.owl	ATP:4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol 2-phosphotransferase activity|4-diphosphocytidyl-2-C-methyl-D-erythritol kinase activity|CDP-ME kinase activity|4-diphosphocytidyl-2C-methyl-D-erythritol kinase activity|CMK activity				RHEA:18437|EC:2.7.1.148|KEGG_REACTION:R05634|MetaCyc:2.7.1.148-RXN							GO:0008698		molecular_function											owl:Class	
GO:1990744	biolink:NamedThing	primary miRNA methylation	The posttranscriptional addition of methyl groups to specific residues in an primary miRNA molecule.	tmpzr1t_l9r_go_relaxed.owl								sp	2015-05-15T05:18:47Z					biological_process											owl:Class	
GO:0150177	biolink:NamedThing	negative regulation of phosphatidylethanolamine metabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of phosphatidylethanolamine metabolic process.	tmpzr1t_l9r_go_relaxed.owl								bc	2020-01-21T14:05:00Z					biological_process											owl:Class	
GO:0003180	biolink:NamedThing	aortic valve morphogenesis	The process in which the structure of the aortic valve is generated and organized.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-10-08T11:29:42Z					biological_process											owl:Class	
GO:0033844	biolink:NamedThing	galactose-6-sulfurylase activity	Catalysis of the elimination of sulfate from the D-galactose 6-sulfate residues of porphyran, producing 3,6-anhydrogalactose residues.	tmpzr1t_l9r_go_relaxed.owl	porphyran sulfatase activity|galactose 6-sulfatase activity|D-galactose-6-sulfate:alkyltransferase (cyclizing) activity|galactose-6-sulfatase activity				EC:2.5.1.5|MetaCyc:2.5.1.5-RXN									molecular_function											owl:Class	
GO:0032970	biolink:NamedThing	regulation of actin filament-based process	Any process that modulates the frequency, rate or extent of any cellular process that depends upon or alters the actin cytoskeleton.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1900480	biolink:NamedThing	regulation of diacylglycerol biosynthetic process	Any process that modulates the frequency, rate or extent of diacylglycerol biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of diacylglycerol anabolism|regulation of diacylglycerol synthesis|regulation of diacylglycerol formation|regulation of diacylglycerol biosynthesis							al	2012-05-02T10:08:59Z					biological_process											owl:Class	
GO:1905917	biolink:NamedThing	positive regulation of cell differentiation involved in phenotypic switching	Any process that activates or increases the frequency, rate or extent of cell differentiation involved in phenotypic switching.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of cell differentiation involved in phenotypic switching|activation of cell differentiation involved in phenotypic switching|up regulation of cell differentiation involved in phenotypic switching|upregulation of cell differentiation involved in phenotypic switching							rph	2017-02-08T12:23:31Z					biological_process											owl:Class	
GO:0018113	biolink:NamedThing	lysine racemase activity	Catalysis of the reaction: L-lysine = D-lysine.	tmpzr1t_l9r_go_relaxed.owl					EC:5.1.1.5|MetaCyc:LYSINE-RACEMASE-RXN|RHEA:22864									molecular_function											owl:Class	
GO:0002121	biolink:NamedThing	inter-male aggressive behavior	Aggressive behavior based on competition between males of the same species over access to resources such as females, dominance, status, etc. and characterized by noise, threats, and is often less injurious.	tmpzr1t_l9r_go_relaxed.owl	inter-male aggression													biological_process											owl:Class	
GO:0102526	biolink:NamedThing	8-demethylnovobiocic acid C8-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine  + 8-desmethylnovobiocic acid <=> S-adenosyl-L-homocysteine  + novobiocic acid + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-14543|EC:2.1.1.284|RHEA:36651									molecular_function											owl:Class	
GO:0038184	biolink:NamedThing	cell surface bile acid receptor signaling pathway	A series of molecular signals initiated by binding of a bile acid to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.	tmpzr1t_l9r_go_relaxed.owl	membrane bile acid receptor signaling pathway							bf	2013-05-16T11:00:42Z					biological_process											owl:Class	
GO:0008671	biolink:NamedThing	2-dehydro-3-deoxygalactonokinase activity	Catalysis of the reaction: 2-dehydro-3-deoxy-D-galactonate + ATP = 6-phospho-2-dehydro-3-deoxy-D-galactonate + ADP + 2 H(+).	tmpzr1t_l9r_go_relaxed.owl	2-keto-3-deoxy-galactonokinase activity|2-keto-3-deoxygalactonokinase activity|2-oxo-3-deoxygalactonate kinase activity|ATP:2-dehydro-3-deoxy-D-galactonate 6-phosphotransferase activity|2-keto-3-deoxygalactonate kinase (phosphorylating)				KEGG_REACTION:R03387|EC:2.7.1.58|RHEA:16525|MetaCyc:DEHYDDEOXGALACTKIN-RXN									molecular_function											owl:Class	
GO:0044613	biolink:NamedThing	nuclear pore central transport channel	The central substructure of the nuclear pore complex (NPC), through which nucleocytoplasmic transport of RNAs, proteins and small molecules occurs. The central transport channel is filled with FG-nucleoporins, which form a selective barrier and provide a series of binding sites for transporter proteins. Characterized S. cerevisiae FG-nucleoporins include Nup159p, Nup145Np, Nup116p, Nup100p, Nsp1p, Nup57p, Nup49p, Nup42p, Nup53p, Nup59p/Asm4p, Nup60p and Nup1. Characterized vertebrate FG-nucleoporins include Nup214, Nup98, Nup62, Nup54, Nup58/45, NLP1, and Nup153.	tmpzr1t_l9r_go_relaxed.owl	nuclear pore central plug|karyopherin docking complex|nuclear pore transport channel|nuclear pore central channel							jl	2012-06-20T01:25:30Z					cellular_component											owl:Class	
GO:0052866	biolink:NamedThing	phosphatidylinositol phosphate phosphatase activity	Catalysis of the reaction: phosphatidylinositol phosphate(n) + H2O = phosphatidylinositol phosphate(n-1) + phosphate. This reaction is the removal of a phosphate group from a phosphatidylinositol phosphate.	tmpzr1t_l9r_go_relaxed.owl	phosphoinositide phosphatase activity							ai	2011-12-13T01:20:17Z					molecular_function											owl:Class	
GO:1903753	biolink:NamedThing	negative regulation of p38MAPK cascade	Any process that stops, prevents or reduces the frequency, rate or extent of p38MAPK cascade.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of p38 cascade|downregulation of p38 cascade|inhibition of p38MAPK cascade|down regulation of p38MAPK cascade|down-regulation of p38MAPK cascade|down-regulation of p38 MAPK cascade|down-regulation of p38 cascade|down regulation of p38 cascade|negative regulation of p38 MAPK cascade|down regulation of p38 MAPK cascade|downregulation of p38 MAPK cascade|inhibition of p38 cascade|downregulation of p38MAPK cascade|inhibition of p38 MAPK cascade							krc	2014-12-12T23:09:26Z					biological_process											owl:Class	
GO:0050474	biolink:NamedThing	(S)-norcoclaurine synthase activity	Catalysis of the reaction: 4-(2-aminoethyl)benzene-1,2-diol + 4-hydroxyphenylacetaldehyde = (S)-norcoclaurine + H2O.	tmpzr1t_l9r_go_relaxed.owl	(S)-norlaudanosoline synthase activity|4-hydroxyphenylacetaldehyde hydro-lyase (adding dopamine)|4-hydroxyphenylacetaldehyde hydro-lyase [adding dopamine; (S)-norcoclaurine-forming]				MetaCyc:S-NORLAUDANOSOLINE-SYNTHASE-RXN|EC:4.2.1.78|RHEA:16173							GO:0050475		molecular_function											owl:Class	
GO:0071967	biolink:NamedThing	lipopolysaccharide core heptosyltransferase activity	Catalysis of the reaction: glucosyl-heptosyl2-KDO2-lipid A-phosphate + ADP-L-glycero-beta-D-manno-heptose = glucosyl-heptosyl3-KDO2-lipid A-phosphate + ADP + H+.	tmpzr1t_l9r_go_relaxed.owl	LPS core heptosyltransferase activity				RHEA:29923|MetaCyc:RXN0-5122			mah	2010-10-14T05:13:31Z					molecular_function											owl:Class	
GO:0008920	biolink:NamedThing	lipopolysaccharide heptosyltransferase activity	Catalysis of the reaction: a lipopolysaccharide + ADP-L-glycero-beta-D-manno-heptose = a heptosylated lipopolysaccharide + ADP + H+.	tmpzr1t_l9r_go_relaxed.owl	LPS heptosyltransferase activity													molecular_function											owl:Class	
GO:1902077	biolink:NamedThing	negative regulation of lateral motor column neuron migration	Any process that stops, prevents or reduces the frequency, rate or extent of lateral motor column neuron migration.	tmpzr1t_l9r_go_relaxed.owl	downregulation of lateral motor column neuron migration|down-regulation of lateral motor column neuron migration|down regulation of lateral motor column neuron migration|inhibition of lateral motor column neuron migration							pr	2013-04-23T14:42:23Z					biological_process											owl:Class	
GO:0060143	biolink:NamedThing	positive regulation of syncytium formation by plasma membrane fusion	Any process that increases the frequency, rate or extent of the formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0018083	biolink:NamedThing	peptidyl-L-3-oxoalanine biosynthetic process from peptidyl-cysteine or peptidyl-serine	The modification of peptidyl-cysteine or peptidyl-serine to peptidyl-L-3-oxoalanine; characteristic of the active sites of arylsulfatases.	tmpzr1t_l9r_go_relaxed.owl	peptidyl-L-3-oxoalanine anabolism from peptidyl-cysteine or peptidyl-serine|peptidyl-L-3-oxoalanine synthesis from peptidyl-cysteine or peptidyl-serine|peptidyl-L-3-oxoalanine formation from peptidyl-cysteine or peptidyl-serine				RESID:AA0185									biological_process											owl:Class	
GO:1901621	biolink:NamedThing	negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning	Any process that stops, prevents or reduces the frequency, rate or extent of smoothened signaling pathway involved in dorsal/ventral neural tube patterning.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of hedgehog signaling pathway involved in dorsal/ventral neural tube patterning|down-regulation of smoothened signalling pathway involved in dorsal/ventral neural tube patterning|down-regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning|down-regulation of hh signaling pathway involved in dorsal/ventral neural tube patterning|inhibition of hh signaling pathway involved in dorsal/ventral neural tube patterning|down regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning|downregulation of smoothened signalling pathway involved in dorsal/ventral neural tube patterning|down regulation of hedgehog signaling pathway involved in dorsal/ventral neural tube patterning|downregulation of hh signaling pathway involved in dorsal/ventral neural tube patterning|negative regulation of hedgehog signaling pathway involved in dorsal/ventral neural tube patterning|negative regulation of smoothened signalling pathway involved in dorsal/ventral neural tube patterning|down regulation of hh signaling pathway involved in dorsal/ventral neural tube patterning|inhibition of smoothened signaling pathway involved in dorsal/ventral neural tube patterning|downregulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning|downregulation of hedgehog signaling pathway involved in dorsal/ventral neural tube patterning|down regulation of smoothened signalling pathway involved in dorsal/ventral neural tube patterning|inhibition of smoothened signalling pathway involved in dorsal/ventral neural tube patterning|negative regulation of hh signaling pathway involved in dorsal/ventral neural tube patterning|inhibition of hedgehog signaling pathway involved in dorsal/ventral neural tube patterning							krc	2012-11-13T20:12:01Z					biological_process											owl:Class	
GO:0033173	biolink:NamedThing	calcineurin-NFAT signaling cascade	Any intracellular signal transduction in which the signal is passed on within the cell by activation of a member of the NFAT protein family as a consequence of NFAT dephosphorylation by Ca(2+)-activated calcineurin. The cascade begins with calcium-dependent activation of the phosphatase calcineurin. Calcineurin dephosphorylates multiple phosphoserine residues on NFAT, resulting in the translocation of NFAT to the nucleus. The cascade ends with regulation of transcription by NFAT. The calcineurin-NFAT cascade lies downstream of many cell surface receptors, including G protein-coupled receptors (GPCRs) and receptor tyrosine kinases (RTKs) that signal to mobilize calcium ions (Ca2+).	tmpzr1t_l9r_go_relaxed.owl	calcineurin-NFAT signalling pathway|calcineurin-NFAT signaling pathway													biological_process											owl:Class	
GO:0051597	biolink:NamedThing	response to methylmercury	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methylmercury stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to MeHg+|response to CH3-Hg+													biological_process											owl:Class	
GO:1902550	biolink:NamedThing	lymphoid lineage cell migration into thymus involved in thymus epithelium morphogenesis	Any lymphoid lineage cell migration into thymus that is involved in thymus epithelium morphogenesis.	tmpzr1t_l9r_go_relaxed.owl	lymphoid lineage restricted progenitor cell migration into thymus involved in thymus epithelium morphogenesis|lymphoid lineage cell migration into thymus involved in thymic epithelium morphogenesis|lymphoid lineage restricted progenitor cell migration into thymus involved in thymic epithelium morphogenesis							pr	2013-12-04T21:13:33Z					biological_process											owl:Class	
GO:0098922	biolink:NamedThing	extrinsic component of dense core granule membrane	The component of the dense core granule membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0097326	biolink:NamedThing	melanocyte adhesion	The attachment of a melanocyte to another cell via adhesion molecules.	tmpzr1t_l9r_go_relaxed.owl								pr	2012-06-08T10:12:03Z					biological_process											owl:Class	
GO:0090136	biolink:NamedThing	epithelial cell-cell adhesion	The attachment of an epithelial cell to another epithelial cell via adhesion molecules.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-12-08T01:56:53Z					biological_process											owl:Class	
GO:0031472	biolink:NamedThing	propanediol degradation polyhedral organelle	An organelle found in bacteria consisting of a proteinaceous coat containing enzymes for the degradation of 1,2-propanediol whose purpose is the protection of the rest of the cell from the toxic propionaldehyde product of the enzyme diol dehydratase.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0031469	biolink:NamedThing	polyhedral organelle	An organelle found in bacteria consisting of a proteinaceous coat containing metabolic enzymes whose purpose is the sequestration or concentration of metabolites and which has the appearance of a polygonal granule by electron microscopy.	tmpzr1t_l9r_go_relaxed.owl	bacterial microcompartment|BAC	https://github.com/geneontology/go-ontology/issues/16852												cellular_component											owl:Class	
GO:0031386	biolink:NamedThing	protein tag	A molecular function exhibited by a protein that is covalently attached (AKA tagged or conjugated) to another protein where it acts as a marker, recognized by the cellular apparatus to target the tagged protein for some cellular process such as modification, sequestration, transport or degradation.	tmpzr1t_l9r_go_relaxed.owl	covalent modifier|ubiquitin|ubiquitin-like protein modifier|protein tagging activity					Use this term to annotate conjugated tags, not for conjugating enzymes. At the time of writing, all known gene products with this activity are ubiquitin-like, either based on overall sequence similarity or the presence of common motifs and structures.								molecular_function											owl:Class	
GO:1904524	biolink:NamedThing	negative regulation of DNA amplification	Any process that stops, prevents or reduces the frequency, rate or extent of DNA amplification.	tmpzr1t_l9r_go_relaxed.owl	down regulation of DNA amplification|inhibition of DNA amplification|down-regulation of DNA amplification|downregulation of DNA amplification							mcc	2015-07-29T16:24:19Z					biological_process											owl:Class	
GO:0033722	biolink:NamedThing	malonate-semialdehyde dehydrogenase activity	Catalysis of the reaction: 3-oxopropanoate + NAD(P)+ + H2O = malonate + NAD(P)H + H+.	tmpzr1t_l9r_go_relaxed.owl	3-oxopropanoate:NAD(P)+ oxidoreductase activity|malonic semialdehyde dehydrogenase activity				MetaCyc:MALONATE-SEMIALDEHYDE-DEHYDROGENASE-RXN|EC:1.2.1.15									molecular_function											owl:Class	
GO:0000487	biolink:NamedThing	maturation of 5.8S rRNA from tetracistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, 2S rRNA, LSU-rRNA)	Any process involved in the maturation of a precursor 5.8S ribosomal RNA (rRNA) molecule into a mature 5.8S rRNA molecule from the pre-rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, the 8.8S rRNA, the 2S rRNA, and the Large Subunit (LSU) in that order from 5' to 3' along the primary transcript.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0040022	biolink:NamedThing	feminization of hermaphroditic germ-line	The determination of female sex and sexual phenotype in the germ-line of the hermaphrodite.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0040021	biolink:NamedThing	hermaphrodite germ-line sex determination	The determination of sex and sexual phenotype in the germ line of a hermaphrodite.	tmpzr1t_l9r_go_relaxed.owl												GO:0042005		biological_process											owl:Class	
GO:0044651	biolink:NamedThing	adhesion of symbiont to host epithelial cell	The attachment of a symbiont to a host epithelial cell via adhesion molecules, general stickiness etc., either directly or indirectly.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-07-12T12:47:09Z					biological_process											owl:Class	
GO:0036256	biolink:NamedThing	cellular response to methylamine	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methylamine stimulus.	tmpzr1t_l9r_go_relaxed.owl								bf	2012-06-15T01:08:00Z					biological_process											owl:Class	
GO:0050000	biolink:NamedThing	chromosome localization	Any process in which a chromosome is transported to, or maintained in, a specific location.	tmpzr1t_l9r_go_relaxed.owl	establishment and maintenance of chromosome localization|establishment and maintenance of chromosome position|chromosome localisation													biological_process											owl:Class	
GO:1905704	biolink:NamedThing	positive regulation of inhibitory synapse assembly	Any process that activates or increases the frequency, rate or extent of inhibitory synapse assembly.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of inhibitory synapse assembly|up regulation of inhibitory synapse formation|activation of inhibitory synapse formation|up-regulation of inhibitory synapse formation|activation of inhibitory synapse assembly|up regulation of inhibitory synapse assembly|upregulation of inhibitory synapse assembly|upregulation of inhibitory synapse formation|positive regulation of inhibitory synapse formation							tb	2016-11-16T18:55:49Z					biological_process											owl:Class	
GO:0051965	biolink:NamedThing	positive regulation of synapse assembly	Any process that activates, maintains or increases the frequency, rate or extent of synapse assembly, the aggregation, arrangement and bonding together of a set of components to form a synapse.	tmpzr1t_l9r_go_relaxed.owl	stimulation of synapse assembly|positive regulation of synaptogenesis|upregulation of synapse assembly|up regulation of synapse assembly|activation of synapse assembly|up-regulation of synapse assembly|positive regulation of synapse biogenesis													biological_process											owl:Class	
GO:1902766	biolink:NamedThing	skeletal muscle satellite cell migration	The orderly movement of a skeletal muscle satellite cell from one site to another. Migration of these cells is a key step in the process of growth and repair of skeletal muscle cells.	tmpzr1t_l9r_go_relaxed.owl								mr	2014-03-10T15:20:28Z					biological_process											owl:Class	
GO:0031817	biolink:NamedThing	P2Y8 nucleotide receptor binding	Binding to a P2Y8 nucleotide receptor.	tmpzr1t_l9r_go_relaxed.owl	P2Y8 nucleotide receptor ligand													molecular_function											owl:Class	
GO:0035883	biolink:NamedThing	enteroendocrine cell differentiation	The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of an enteroendocrine cell. Enteroendocrine cells are hormonally active epithelial cells in the gut that constitute the diffuse neuroendocrine system.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-06-06T11:48:51Z					biological_process											owl:Class	
GO:0035685	biolink:NamedThing	helper T cell diapedesis	The passage of a helper T cell between the tight junctions of endothelial cells lining blood vessels, typically the fourth and final step of cellular extravasation.	tmpzr1t_l9r_go_relaxed.owl	T-helper cell diapedesis|helper T-cell diapedesis							bf	2011-02-23T01:11:52Z					biological_process											owl:Class	
GO:0050904	biolink:NamedThing	diapedesis	The passage of a leukocyte between the tight junctions of endothelial cells lining blood vessels, typically the fourth and final step of cellular extravasation.	tmpzr1t_l9r_go_relaxed.owl						Note that the term diapedesis, although sometimes used as a direct synonym for cellular extravasation, is used here for the specific final step of the process, in concordance with recent reviews of the topic.								biological_process											owl:Class	
GO:0031648	biolink:NamedThing	protein destabilization	Any process that decreases the stability of a protein, making it more vulnerable to degradative processes or aggregation.	tmpzr1t_l9r_go_relaxed.owl	protein destabilisation|negative regulation of protein stability													biological_process											owl:Class	
GO:0031647	biolink:NamedThing	regulation of protein stability	Any process that affects the structure and integrity of a protein, altering the likelihood of its degradation or aggregation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0035260	biolink:NamedThing	internal genitalia morphogenesis	The process in which the anatomical structures of the internal genitalia are generated and organized. The internal genitalia are the internal sex organs such as the uterine tube, the uterus and the vagina in female mammals, and the testis, seminal vesicle, ejaculatory duct and prostate in male mammals.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0046406	biolink:NamedThing	magnesium protoporphyrin IX methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine(1+) + magnesium protoporphyrin IX = S-adenosyl-L-homocysteine + H(+) + magnesium protoporphyrin IX 13-monomethyl ester.	tmpzr1t_l9r_go_relaxed.owl	(-)-S-adenosyl-L-methionine:magnesium-protoporphyrin IX methyltransferase activity|S-adenosyl-L-methionine:magnesium-protoporphyrin O-methyltransferase activity|S-adenosyl-L-methionine:magnesium-protoporphyrin-IX O-methyltransferase activity|S-adenosylmethionine-magnesium protoporphyrin methyltransferase activity|S-adenosylmethioninemagnesium protoporphyrin methyltransferase activity|Mg-protoporphyrin IX methyltransferase activity|S-adenosyl-L-methionine:Mg protoporphyrin methyltransferase activity|magnesium-protoporphyrin O-methyltransferase activity				EC:2.1.1.11|RHEA:17809|MetaCyc:RXN-MG-PROTOPORPHYRIN-METHYLESTER-SYN|KEGG_REACTION:R04237									molecular_function											owl:Class	
GO:0008793	biolink:NamedThing	aromatic-amino-acid:2-oxoglutarate aminotransferase activity	Catalysis of the reaction: an aromatic amino acid + 2-oxoglutarate = an aromatic oxo acid + L-glutamate.	tmpzr1t_l9r_go_relaxed.owl	aromatic amino acid transferase activity|aromatic-amino-acid transaminase activity|aromatic amino acid aminotransferase activity|aromatic aminotransferase activity|ArAT				EC:2.6.1.57|RHEA:17533|MetaCyc:2.6.1.57-RXN|UM-BBD_reactionID:r0297									molecular_function											owl:Class	
GO:0036081	biolink:NamedThing	extracellular ammonia-gated ion channel activity	Enables the transmembrane transfer of an ion by a channel that opens when extracellular ammonia (NH3) has been bound by the channel complex or one of its constituent parts.	tmpzr1t_l9r_go_relaxed.owl	ionotropic ammonia receptor activity							bf	2011-12-20T04:47:48Z					molecular_function											owl:Class	
GO:0052102	biolink:NamedThing	positive regulation by symbiont of defense-related host calcium-dependent protein kinase pathway	Any process in which an organism activates, maintains or increases the frequency, rate or extent of the host calcium-dependent protein kinase pathway during the host defense response. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	up-regulation by symbiont of defense-related host calcium-dependent protein kinase pathway|positive regulation of defense-related host CDPK pathway by organism|activation by symbiont of defense-related host calcium-dependent protein kinase pathway|stimulation by symbiont of defense-related host calcium-dependent protein kinase pathway|upregulation by symbiont of defense-related host calcium-dependent protein kinase pathway|positive regulation by organism of defense-related calcium-dependent protein kinase pathway in other organism involved in symbiotic interaction|up regulation by symbiont of defense-related host calcium-dependent protein kinase pathway											GO:0052287		biological_process											owl:Class	
GO:0010841	biolink:NamedThing	positive regulation of circadian sleep/wake cycle, wakefulness	Any process that increases the frequency, or extent of the wakeful phase of the circadian sleep/wake cycle. The wakeful phase is the part of the circadian sleep/wake cycle where the organism is not asleep.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0036067	biolink:NamedThing	light-dependent chlorophyll biosynthetic process	The chemical reactions and pathways resulting in the formation of chlorophyll, any compound of magnesium complexed in a porphyrin (tetrapyrrole) ring and which functions as a photosynthetic pigment, from less complex precursors, which occur in the presence of light.	tmpzr1t_l9r_go_relaxed.owl	light-dependent chlorophyll synthesis|light-dependent chlorophyll formation|light-dependent chlorophyll anabolism|light dependent chlorophyll biosynthetic process|light-dependent chlorophyll biosynthesis							bf	2011-12-15T04:42:47Z					biological_process											owl:Class	
GO:0036371	biolink:NamedThing	protein localization to T-tubule	A process in which a protein is transported to, or maintained in, the T-tubule. The T-tubule is an invagination of the plasma membrane of a muscle cell that extends inward from the cell surface around each myofibril.	tmpzr1t_l9r_go_relaxed.owl	protein localization to T tubule|protein localisation to T-tubule|protein localization to transverse tubule							bf	2012-10-08T17:10:29Z					biological_process											owl:Class	
GO:0097573	biolink:NamedThing	glutathione oxidoreductase activity	Catalysis of the reaction: protein-S-S-glutathione + glutathione-SH = protein-SH + glutathione-S-S-glutathione.	tmpzr1t_l9r_go_relaxed.owl						Note that this activity is different from GO:0015038 'glutathione disulfide oxidoreductase activity'. See PMID:18992757: "Grxs [glutaredoxins] can also reduce mixed disulfides between proteins or low molecular weight thiols and GSH in reactions that require only their N-terminal active- site cysteine. It is important to note that the reduction of glutathionylated substrates through the monothiol mechanism seems to be the major activity of Grxs; all dithiol Grxs described so far catalyze these reactions, but not all dithiol Grxs catalyze the reduction of protein disulfides by the dithiol mechanism".		pr	2014-02-19T13:41:38Z					molecular_function											owl:Class	
GO:0150141	biolink:NamedThing	negative regulation of CD86 production	Any process that stops, prevents or reduces the frequency, rate or extent of CD86 biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of CD86 biosynthetic process							bc	2019-12-08T09:33:39Z					biological_process											owl:Class	
GO:0140593	biolink:NamedThing	host apoplast	The apoplast region surrounding a host plant cell. Plants may be described as having two major compartments: the living symplast and the non-living apoplast. The apoplast is external to the plasma membrane and includes cell walls, intercellular spaces and the lumen of dead structures such as xylem vessels. Water and solutes pass freely through it. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	host cell apoplast	https://github.com/geneontology/go-ontology/issues/21343|https://github.com/geneontology/go-ontology/issues/20814						pg	2021-02-09T18:56:11Z					cellular_component											owl:Class	
GO:0034538	biolink:NamedThing	3-methylsalicylaldehyde dehydrogenase activity	Catalysis of the reaction: 3-methylsalicylaldehyde + NAD+ = 3-methylsalicylate + NADH + H+.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0784									molecular_function											owl:Class	
GO:0008849	biolink:NamedThing	enterochelin esterase activity	Catalysis of the reaction: enterobactin + 3 H2O = 3 N-23-dihydroxybenzoyl-L-serine + 3 H+.	tmpzr1t_l9r_go_relaxed.owl	enterobactin esterase activity				MetaCyc:RXN0-1661|RHEA:28018									molecular_function											owl:Class	
GO:0110123	biolink:NamedThing	regulation of myotube cell migration	Any process that modulates the frequency, rate or extent of myotube cell migration.	tmpzr1t_l9r_go_relaxed.owl								kmv	2018-08-22T21:06:53Z					biological_process											owl:Class	
GO:0042899	biolink:NamedThing	arabinan transmembrane transport	The process in which arabinan is transported across a lipid bilayer, from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	arabinan transport													biological_process											owl:Class	
GO:0009747	biolink:NamedThing	hexokinase-dependent signaling	A series of molecular signals mediated by hexose and dependent on the detection of hexokinase.	tmpzr1t_l9r_go_relaxed.owl	hexokinase-dependent signalling													biological_process											owl:Class	
GO:0102940	biolink:NamedThing	phloroglucinol O-methyltransferase activity	Catalysis of the reaction: phloroglucinol + S-adenosyl-L-methionine  = H+ + 3,5-dihydroxyanisole + S-adenosyl-L-homocysteine.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-9020									molecular_function											owl:Class	
GO:0036210	biolink:NamedThing	protein modification process in other organism	The covalent alteration performed by one organism of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications) in another organism. Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification).	tmpzr1t_l9r_go_relaxed.owl	protein modification in other organism							bf	2012-04-26T01:29:29Z					biological_process											owl:Class	
GO:0047529	biolink:NamedThing	2,3-dimethylmalate lyase activity	Catalysis of the reaction: (2R,3S)-2,3-dimethylmalate = propanoate + pyruvate.	tmpzr1t_l9r_go_relaxed.owl	2,3-dimethylmalate pyruvate-lyase activity|(2R,3S)-2,3-dimethylmalate pyruvate-lyase (propanoate-forming)|(2R,3S)-2,3-dimethylmalate pyruvate-lyase activity				MetaCyc:23-DIMETHYLMALATE-LYASE-RXN|EC:4.1.3.32|RHEA:10472|KEGG_REACTION:R01355									molecular_function											owl:Class	
GO:0052630	biolink:NamedThing	UDP-N-acetylgalactosamine diphosphorylase activity	Catalysis of the reaction: UTP + N-acetyl-alpha-D-galactosamine 1-phosphate = diphosphate + UDP-N-acetyl-D-galactosamine.	tmpzr1t_l9r_go_relaxed.owl	uridine diphosphate-N-acetylgalactosamine pyrophosphorylase activity|UDP-N-acetylgalactosamine pyrophosphorylase activity|UTP:2-acetamido-2-deoxy-alpha-D-galactose-1-phosphate uridylyltransferase activity|UDP-acetylgalactosamine pyrophosphorylase activity|uridine diphosphoacetylgalactosamine pyrophosphorylase activity|N-acetylgalactosamine-1-phosphate uridyltransferase activity|UDP-GalNAc pyrophosphorylase activity|uridine diphosphoacetylgalactosamine phosphorylase activity|N-acetylgalactosamine 1-phosphate uridylyltransferase|UTP:N-acetyl-alpha-D-galactosamine-1-phosphate uridylyltransferase activity				RHEA:34363|EC:2.7.7.83									molecular_function											owl:Class	
GO:0060648	biolink:NamedThing	mammary gland bud morphogenesis	The process in which anatomical structures of the mammary gland buds are generated and organized. Mammary gland buds form by an outpocketing of the mammary placodes and grow to invade the mammary fat, when they form the mammary cord.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-05-29T08:42:22Z					biological_process											owl:Class	
GO:0015747	biolink:NamedThing	urate transport	The directed movement of urate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	uric acid transport|urate transmembrane transport													biological_process											owl:Class	
GO:0060990	biolink:NamedThing	lipid tube assembly involved in organelle fission	The aggregation, arrangement and bonding together of a set of macromolecules to form a macromolecular complex that contains a tube of lipid surrounded by a protein coat involved in membrane shaping of vesicle membranes as organelles undergo fission.	tmpzr1t_l9r_go_relaxed.owl	lipid tubulation involved in organelle fission							dph	2010-01-11T02:14:48Z					biological_process											owl:Class	
GO:0043182	biolink:NamedThing	vacuolar sequestering of sodium ion	The process of transporting sodium ions into, and confining within, a vacuole.	tmpzr1t_l9r_go_relaxed.owl	sodium ion (Na+) storage in vacuole|vacuolar sequestration of sodium ion (Na+)|sequestering of sodium ion (Na+) in vacuole|vacuolar sequestering of sodium ion (Na+)|vacuolar sodium ion (Na+) storage|sequestration of sodium ion (Na+) in vacuole|vacuolar sodium ion (Na+) retention|sodium ion (Na+) retention in vacuole													biological_process											owl:Class	
GO:0043181	biolink:NamedThing	vacuolar sequestering	The process of transporting a substance into, and confining within, a vacuole.	tmpzr1t_l9r_go_relaxed.owl	vacuolar retention|vacuolar sequestration|vacuolar storage|storage in vacuole|retention in vacuole|sequestration in vacuole|sequestering in vacuole													biological_process											owl:Class	
GO:1901719	biolink:NamedThing	regulation of NMS complex assembly	Any process that modulates the frequency, rate or extent of NMS complex assembly. The NMS complex is involved in chromosome segregation.	tmpzr1t_l9r_go_relaxed.owl	regulation of NMS complex association involved in chromosome segregation|regulation of NMS complex assembly involved in kinetochore assembly|regulation of KMN network assembly involved in chromosome segregation|regulation of KMN complex assembly involved in chromosome segregation							jl	2012-12-20T11:44:17Z					biological_process											owl:Class	
GO:0018450	biolink:NamedThing	myrtenol dehydrogenase activity	Catalysis of the reaction: myrtenol + O2 + 2 H+ + 2 e- = 2 H2O + myrtenal.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0710									molecular_function											owl:Class	
GO:0002619	biolink:NamedThing	regulation of non-professional antigen presenting cell antigen processing and presentation	Any process that modulates the frequency, rate, or extent of non-professional antigen presenting cell antigen processing and presentation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0010567	biolink:NamedThing	regulation of ketone catabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a ketone, carried out by individual cells.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1990065	biolink:NamedThing	Dxr protein complex	A protein complex that is involved in the MEP pathway of IPP biosynthesis. It catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).	tmpzr1t_l9r_go_relaxed.owl	1-deoxy-D-xylulose 5-phosphate reductoisomerase complex							bhm	2013-03-27T16:58:54Z					cellular_component											owl:Class	
GO:0004846	biolink:NamedThing	urate oxidase activity	Catalysis of the reaction: urate + O2 + H2O = 5-hydroxyisourate + hydrogen peroxide.	tmpzr1t_l9r_go_relaxed.owl	urate:oxygen oxidoreductase activity|uricase II activity|uricase activity|uric acid oxidase activity				UM-BBD_reactionID:r1322|MetaCyc:URATE-OXIDASE-RXN|EC:1.7.3.3|RHEA:21368									molecular_function											owl:Class	
GO:1904803	biolink:NamedThing	regulation of translation involved in cellular response to UV	Any regulation of translation that is involved in cellular response to UV.	tmpzr1t_l9r_go_relaxed.owl	regulation of protein synthesis involved in cellular response to UV|regulation of protein biosynthesis involved in cellular response to UV|regulation of protein anabolism involved in cellular response to UV|regulation of protein formation involved in cellular response to UV|regulation of translation involved in cellular response to ultraviolet radiation stimulus|regulation of translation involved in cellular response to ultraviolet light stimulus|regulation of translation involved in cellular response to UV light stimulus|regulation of translation involved in cellular response to UV radiation stimulus							mah	2015-11-10T12:12:41Z					biological_process											owl:Class	
GO:0035520	biolink:NamedThing	monoubiquitinated protein deubiquitination	The removal of the ubiquitin group from a monoubiquitinated protein.	tmpzr1t_l9r_go_relaxed.owl	monoubiquitinated protein deubiquitinylation|monoubiquitinated protein deubiquitylation							bf	2010-05-04T04:28:38Z					biological_process											owl:Class	
GO:0070820	biolink:NamedThing	tertiary granule	A secretory granule that contains cathepsin and gelatinase and is readily exocytosed upon cell activation; found primarily in mature neutrophil cells.	tmpzr1t_l9r_go_relaxed.owl	gelatinase granule							mah	2009-07-20T03:57:00Z					cellular_component											owl:Class	
GO:0031482	biolink:NamedThing	myosin XII complex	A myosin complex containing one or more class XII myosin heavy chains and associated light chains; myosin XII contains a large tail region with two MyTH4 domains and a short region of coiled coil.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0050563	biolink:NamedThing	trans-feruloyl-CoA synthase activity	Catalysis of the reaction: ATP + CoA + trans-ferulate = (E)-feruloyl-CoA + ADP + phosphate.	tmpzr1t_l9r_go_relaxed.owl	trans-feruloyl-CoA synthetase activity|ferulate-CoA ligase activity|trans-ferulate:CoASH ligase (ATP-hydrolysing)				EC:6.2.1.34|RHEA:19389|MetaCyc:6.2.1.34-RXN			hjd	2020-07-30T15:20:51Z			GO:0106287		molecular_function											owl:Class	
GO:0036248	biolink:NamedThing	phytochelatin 4 import into vacuole	The directed movement of phytochelatin 4 (PC4) into the vacuole. Phytochelatin 4 is a glutathione-related peptide composed of (gamma-Glu-Cys)n-Gly where n=4, and where the Glu and Cys residues are linked through a gamma-carboxylamide bond.	tmpzr1t_l9r_go_relaxed.owl	PC4 import into vacuole							bf	2012-05-31T11:12:08Z					biological_process											owl:Class	
GO:1902603	biolink:NamedThing	carnitine transmembrane transport	The directed movement of carnitine across a membrane.	tmpzr1t_l9r_go_relaxed.owl								pr	2013-12-20T11:09:11Z					biological_process											owl:Class	
GO:0098964	biolink:NamedThing	anterograde dendritic transport of messenger ribonucleoprotein complex	The directed movement of a messenger ribonucleoprotein complex along microtubules in nerve cell dendrites towards the postsynapse.	tmpzr1t_l9r_go_relaxed.owl	anterograde dendritic transport of mRNA RNP complex													biological_process											owl:Class	
GO:0098937	biolink:NamedThing	anterograde dendritic transport	The directed movement of organelles or molecules along microtubules from the cell body toward the postsynapse in dendrites.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0006190	biolink:NamedThing	inosine salvage	Any process that generates inosine, hypoxanthine riboside, from derivatives of it without de novo synthesis.	tmpzr1t_l9r_go_relaxed.owl	adenine, hypoxanthine and their nucleoside salvage|guanine, xanthine and their nucleoside salvage													biological_process											owl:Class	
GO:0010245	biolink:NamedThing	radial microtubular system formation	Formation of radial microtubular systems during male meiotic cytokinesis in plants.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0004447	biolink:NamedThing	iodide peroxidase activity	Catalysis of the reaction: iodide + hydrogen peroxide = iodine + 2 H2O.	tmpzr1t_l9r_go_relaxed.owl	thyroid peroxidase activity|TPO activity|thyroperoxidase activity|iodinase activity	https://github.com/geneontology/go-ontology/issues/21027			MetaCyc:IODIDE-PEROXIDASE-RXN|EC:1.11.1.8									molecular_function											owl:Class	
GO:0032186	biolink:NamedThing	cellular bud neck septin ring organization	Control of the formation, spatial distribution, and breakdown of a septin ring located at the bud neck.	tmpzr1t_l9r_go_relaxed.owl	cellular bud neck septin ring organisation													biological_process											owl:Class	
GO:0098763	biolink:NamedThing	mitotic cell cycle phase	One of the distinct periods or stages into which the mitotic cell cycle is divided. Each phase is characterized by the occurrence of specific biochemical and morphological events.	tmpzr1t_l9r_go_relaxed.owl						This term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation should be to 'regulation of x/y phase transition' or to a process which occurs during the reported phase (e.g. mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).								biological_process											owl:Class	
GO:0035609	biolink:NamedThing	C-terminal protein deglutamylation	The removal of a C-terminal, gene-encoded glutamate residue from a protein.	tmpzr1t_l9r_go_relaxed.owl	protein primary sequence deglutamylation							bf	2010-11-18T01:06:00Z					biological_process											owl:Class	
GO:0046106	biolink:NamedThing	thymine biosynthetic process	The chemical reactions and pathways resulting in the formation of thymine, 5-methyluracil, one of the two major pyrimidine bases present (as thymidine) in DNA but not found in RNA other than (as ribothymidine) in transfer RNA, where it is a minor base.	tmpzr1t_l9r_go_relaxed.owl	thymine formation|thymine anabolism|thymine biosynthesis|thymine synthesis													biological_process											owl:Class	
GO:0070481	biolink:NamedThing	nuclear-transcribed mRNA catabolic process, non-stop decay	The chemical reactions and pathways resulting in the breakdown of the transcript body of a nuclear-transcribed mRNA that is lacking a stop codon.	tmpzr1t_l9r_go_relaxed.owl	non-stop decay|non-stop mRNA decay|nuclear-transcribed mRNA catabolism, non-stop decay|nonstop mRNA decay|nuclear-transcribed mRNA breakdown, non-stop decay|nuclear-transcribed mRNA degradation, non-stop decay													biological_process											owl:Class	
GO:0032475	biolink:NamedThing	otolith formation	The process that gives rise to an otolith. This process pertains to the initial formation of a structure from unspecified parts.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0019640	biolink:NamedThing	glucuronate catabolic process to xylulose 5-phosphate	The chemical reactions and pathways resulting in the breakdown of glucuronate into other compounds, including xylulose 5-phosphate.	tmpzr1t_l9r_go_relaxed.owl	glucuronate degradation to xylulose 5-phosphate|glucuronate breakdown to xylulose 5-phosphate													biological_process											owl:Class	
GO:0060156	biolink:NamedThing	milk ejection reflex	A reflex that occurs in response to suckling, beginning with a nerve impulse from a receptor in the mammary gland and ending with the ejection of milk from the gland. Signaling never reaches a level of consciousness.	tmpzr1t_l9r_go_relaxed.owl	milk ejection													biological_process											owl:Class	
GO:0034944	biolink:NamedThing	3-hydroxy-2,6-dimethyl-5-methylene-heptanoyl-CoA dehydrogenase activity	Catalysis of the reaction: 3-hydroxy-2,6-dimethyl-5-methylene-heptanoyl-CoA + NAD+ = 2,6-dimethyl-5-methylene-3-oxo-heptanoyl-CoA + NADH+ + H+.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0986									molecular_function											owl:Class	
GO:0052661	biolink:NamedThing	S-lactaldehyde reductase activity	Catalysis of the reaction: (S)-propane-1,2-diol + NAD+ = (S)-lactaldehyde + NADH + H+.	tmpzr1t_l9r_go_relaxed.owl	(S)-propane-1,2-diol:NAD+ oxidoreductase activity|L-lactaldehyde:propanediol oxidoreductase activity				MetaCyc:LACTALDREDUCT-RXN|RHEA:15933|KEGG_REACTION:R02258									molecular_function											owl:Class	
GO:0008912	biolink:NamedThing	lactaldehyde reductase activity	Catalysis of the reaction: propane-1,2-diol + NAD+ = lactaldehyde + NADH + H+.	tmpzr1t_l9r_go_relaxed.owl	propanediol:nicotinamide adenine dinucleotide (NAD) oxidoreductase activity|(R)- or (S)-propane-1,2-diol:NAD+ oxidoreductase activity|lactaldehyde:propanediol oxidoreductase activity|propanediol oxidoreductase activity				EC:1.1.1.77									molecular_function											owl:Class	
GO:0046727	biolink:NamedThing	capsomere	Any of the protein subunits that comprise the closed shell or coat (capsid) of certain viruses.	tmpzr1t_l9r_go_relaxed.owl	capsomer				Wikipedia:Capsomere									cellular_component											owl:Class	
GO:0036354	biolink:NamedThing	2-desacetyl-2-hydroxyethyl bacteriochlorophyllide a dehydrogenase activity	Catalysis of the reaction: 2-desacetyl-2-hydroxyethyl bacteriochlorophyllide a = bacteriochlorophyllide a + 2 H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-8787|RHEA:19733			bf	2012-09-19T14:46:31Z					molecular_function											owl:Class	
GO:0120065	biolink:NamedThing	pyloric antrum smooth muscle contraction	A process in which force is generated within gastric smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the widest part of the pylorus that is continuous with the body of the stomach.	tmpzr1t_l9r_go_relaxed.owl	antrum smooth muscle contraction							krc	2017-06-13T22:36:20Z					biological_process											owl:Class	
GO:0045794	biolink:NamedThing	negative regulation of cell volume	Any process that decreases cell volume.	tmpzr1t_l9r_go_relaxed.owl	RVD|cell regulatory volume decrease													biological_process											owl:Class	
GO:0070300	biolink:NamedThing	phosphatidic acid binding	Binding to phosphatidic acid, any of a class of glycerol phosphate in which both the remaining hydroxyl groups of the glycerol moiety are esterified with fatty acids.	tmpzr1t_l9r_go_relaxed.owl	phosphatidate binding													molecular_function											owl:Class	
GO:0002438	biolink:NamedThing	acute inflammatory response to antigenic stimulus	An acute inflammatory response to an antigenic stimulus. An acute inflammatory response occurs within a matter of minutes or hours, and either resolves within a few days or becomes a chronic inflammatory response.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0006011	biolink:NamedThing	UDP-glucose metabolic process	The chemical reactions and pathways involving UDP-glucose, uridinediphosphoglucose, a substance composed of glucose in glycosidic linkage with uridine diphosphate.	tmpzr1t_l9r_go_relaxed.owl	UDP-glucose metabolism													biological_process											owl:Class	
GO:0033768	biolink:NamedThing	SUMO-targeted ubiquitin ligase complex	A nuclear ubiquitin ligase complex that specifically targets SUMOylated proteins; the complex is formed of homodimers or heterodimers of RNF4 family ubiquitin ligases and is conserved in eukaryotes.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0009641	biolink:NamedThing	shade avoidance	Shade avoidance is a set of responses that plants display when they are subjected to the shade of another plant. It often includes elongation, altered flowering time, increased apical dominance and altered partitioning of resources. Plants are able to distinguish between the shade of an inanimate object (e.g. a rock) and the shade of another plant due to the altered balance between red and far-red light in the shade of a plant; this balance between red and far-red light is perceived by phytochrome.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Shade_avoidance									biological_process											owl:Class	
GO:0031728	biolink:NamedThing	CCR3 chemokine receptor binding	Binding to a CCR3 chemokine receptor.	tmpzr1t_l9r_go_relaxed.owl	CCR3 chemokine receptor ligand|eosinophil eotaxin receptor binding													molecular_function											owl:Class	
GO:0150001	biolink:NamedThing	primary dendrite	A dendrite emerging from the cell body (the soma) of a neuron.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0034840	biolink:NamedThing	3-hydroxymenthone dehydrogenase activity	Catalysis of the reaction: (5R)-3-hydroxymenthone + NAD+ = mentha-1,3-dione + NADH + H+.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r1185									molecular_function											owl:Class	
GO:0001785	biolink:NamedThing	prostaglandin J receptor activity	Combining with prostaglandin J (PGJ(2)), a metabolite of prostaglandin D (PGD(2)) to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	PGJ(2) receptor activity|PGJ receptor activity													molecular_function											owl:Class	
GO:0008043	biolink:NamedThing	intracellular ferritin complex	A ferritin complex located in the cell. Intracellular ferritin complexes contain 24 subunits, in a mixture of L (light) chains and H (heavy) chains.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0051388	biolink:NamedThing	positive regulation of neurotrophin TRK receptor signaling pathway	Any process that activates or increases the frequency, rate or extent of the neurotrophin TRK receptor signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	upregulation of nerve growth factor receptor signaling pathway|up regulation of nerve growth factor receptor signaling pathway|stimulation of nerve growth factor receptor signaling pathway|activation of nerve growth factor receptor signaling pathway|positive regulation of NGF receptor signaling pathway|positive regulation of NGF receptor signalling pathway|positive regulation of nerve growth factor receptor signalling pathway|up-regulation of nerve growth factor receptor signaling pathway|positive regulation of nerve growth factor receptor signaling pathway													biological_process											owl:Class	
GO:0070691	biolink:NamedThing	P-TEFb complex	A dimeric positive transcription elongation factor complex b that comprises a cyclin-dependent kinase containing the catalytic subunit, Cdk9, and a regulatory subunit, cyclin T.	tmpzr1t_l9r_go_relaxed.owl	cyclin-dependent kinase 9 (Cdk9)-cyclin T2 complex|Sgv1/Bur2 complex|dimeric positive transcription elongation factor complex b|Bur1/Bur2 complex|cyclin-dependent kinase 9 (Cdk9)-cyclin T1 complex							mah	2009-06-03T03:12:56Z					cellular_component											owl:Class	
GO:0008024	biolink:NamedThing	cyclin/CDK positive transcription elongation factor complex	A transcription elongation factor complex that facilitates the transition from abortive to productive elongation by phosphorylating the CTD domain of the large subunit of DNA-directed RNA polymerase II, holoenzyme. Contains a cyclin and a cyclin-dependent protein kinase catalytic subunit.	tmpzr1t_l9r_go_relaxed.owl	positive transcription elongation factor complex b					See also the cellular component terms 'cyclin-dependent protein kinase activating kinase holoenzyme complex ; GO:0019907' and 'DNA-directed RNA polymerase II, holoenzyme ; GO:0016591'.								cellular_component											owl:Class	
GO:0019857	biolink:NamedThing	5-methylcytosine metabolic process	The chemical reactions and pathways involving 5-methylcytosine, a methylated base of DNA.	tmpzr1t_l9r_go_relaxed.owl	5-methylcytosine metabolism													biological_process											owl:Class	
GO:0047517	biolink:NamedThing	1,4-beta-D-xylan synthase activity	Catalysis of the reaction: UDP-D-xylose + [(1->4)-beta-D-xylan](n) = UDP + [(1->4)-beta-D-xylan](n+1).	tmpzr1t_l9r_go_relaxed.owl	xylan synthetase activity|xylan synthase activity|1,4-beta-xylan synthase activity|UDP-D-xylose:1,4-beta-D-xylan 4-beta-D-xylosyltransferase activity|uridine diphosphoxylose-1,4-beta-xylan xylosyltransferase activity				RHEA:15289|EC:2.4.2.24|MetaCyc:RXN-9104									molecular_function											owl:Class	
GO:0060752	biolink:NamedThing	intestinal phytosterol absorption	Any process in which phytosterols are taken up from the contents of the intestine.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-06-22T02:08:43Z					biological_process											owl:Class	
GO:0030942	biolink:NamedThing	endoplasmic reticulum signal peptide binding	Binding to an endoplasmic reticulum signal peptide, a specific peptide sequence that acts as a signal to localize the protein within the endoplasmic reticulum.	tmpzr1t_l9r_go_relaxed.owl	ER signal peptide binding													molecular_function											owl:Class	
GO:0140562	biolink:NamedThing	EGF-domain serine xylosyltransferase activity	Catalyses the reaction: UDP-alpha-D-xylose + [protein with EGF-like domain]-L-serine <=> UDP + [protein with EGF-like domain]-3-O-(beta-D-xylosyl)-L-serine.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/16869			RHEA:62016|EC:2.4.2.63			pg	2020-11-25T14:30:56Z					molecular_function											owl:Class	
GO:0006192	biolink:NamedThing	IDP phosphorylation	The process of introducing a phosphate group into IDP, inosine (5'-)diphosphate, to produce ITP.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0002271	biolink:NamedThing	plasmacytoid dendritic cell activation involved in immune response	A change in the morphology or behavior of a plasmacytoid dendritic cell resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response.	tmpzr1t_l9r_go_relaxed.owl	plasmacytoid dendritic cell activation during immune response													biological_process											owl:Class	
GO:1902813	biolink:NamedThing	negative regulation of BMP signaling pathway involved in determination of lateral mesoderm left/right asymmetry	Any process that stops, prevents or reduces the frequency, rate or extent of BMP signaling pathway involved in determination of lateral mesoderm left/right asymmetry.	tmpzr1t_l9r_go_relaxed.owl	down regulation of BMP signaling pathway involved in determination of lateral mesoderm left/right asymmetry|negative regulation of BMP signalling pathway involved in determination of lateral mesoderm left/right asymmetry|inhibition of BMP signaling pathway involved in lateral mesoderm left/right asymmetry determination|downregulation of BMP signaling pathway involved in determination of lateral mesoderm left/right asymmetry|down-regulation of BMP signaling pathway involved in determination of lateral mesoderm left/right asymmetry|down-regulation of BMP signaling pathway involved in lateral mesoderm left/right asymmetry determination|inhibition of BMP signalling pathway involved in determination of lateral mesoderm left/right asymmetry|inhibition of BMP signaling pathway involved in determination of lateral mesoderm left/right asymmetry|downregulation of BMP signalling pathway involved in determination of lateral mesoderm left/right asymmetry|down regulation of BMP signalling pathway involved in determination of lateral mesoderm left/right asymmetry|negative regulation of BMP signaling pathway involved in lateral mesoderm left/right asymmetry determination|down regulation of BMP signaling pathway involved in lateral mesoderm left/right asymmetry determination|downregulation of BMP signaling pathway involved in lateral mesoderm left/right asymmetry determination|down-regulation of BMP signalling pathway involved in determination of lateral mesoderm left/right asymmetry							mr	2014-03-26T21:18:50Z					biological_process											owl:Class	
GO:0098962	biolink:NamedThing	regulation of postsynaptic neurotransmitter receptor activity	Any process that modulates the frequency, rate or extent of neurotransmitter receptor activity involved in synaptic transmission. Modulation may be via an effect on ligand affinity, or effector funtion such as ion selectivity or pore opening/closing in ionotropic receptors.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0030998	biolink:NamedThing	linear element	A proteinaceous scaffold associated with fission yeast chromosomes during meiotic prophase. Linear elements consist of a protein complex, LinE, with four main structural components (Rec10, Rec25, Rec27, and Mug20 in S. pombe) associated with chromatin. The resulting structure is related to but not equivalent to the synaptonemal complex.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:1902501	biolink:NamedThing	lysosomal HOPS complex	Any HOPS complex that is part of a lysosomal membrane.	tmpzr1t_l9r_go_relaxed.owl	lysosomal membrane HOPS complex							tb	2013-11-14T00:09:59Z					cellular_component											owl:Class	
GO:0004345	biolink:NamedThing	glucose-6-phosphate dehydrogenase activity	Catalysis of the reaction: D-glucose 6-phosphate + NADP+ = D-glucono-1,5-lactone 6-phosphate + NADPH + H+.	tmpzr1t_l9r_go_relaxed.owl	D-glucose-6-phosphate:NADP+ 1-oxidoreductase activity|Zwischenferment|G6PDH|6-phosphoglucose dehydrogenas|glucose 6-phosphate dehydrogenase (NADP) activity|Entner-doudoroff enzyme|glucose-6-phosphate 1-dehydrogenase activity|NADP-glucose-6-phosphate dehydrogenase activity|6-phosphoglucose dehydrogenase activity|D-glucose 6-phosphate dehydrogenase activity|GDH|G6PD activity|NADP-dependent glucose 6-phosphate dehydrogenase activity				Reactome:R-HSA-70377|RHEA:15841|MetaCyc:GLU6PDEHYDROG-RXN|EC:1.1.1.49									molecular_function											owl:Class	
GO:0030156	biolink:NamedThing	benzodiazepine receptor binding	Binding to a peripheral benzodiazepine receptor (PBR).	tmpzr1t_l9r_go_relaxed.owl	benzodiazepine receptor ligand|diazepam binding inhibitor activity													molecular_function											owl:Class	
GO:1903133	biolink:NamedThing	negative regulation of tube lumen cavitation	Any process that stops, prevents or reduces the frequency, rate or extent of tube lumen cavitation.	tmpzr1t_l9r_go_relaxed.owl	inhibition of tube lumen cavitation							dph	2014-06-25T20:19:04Z					biological_process											owl:Class	
GO:0006169	biolink:NamedThing	adenosine salvage	Any process that generates adenosine, adenine riboside, from derivatives of it without de novo synthesis.	tmpzr1t_l9r_go_relaxed.owl	adenine, hypoxanthine and their nucleoside salvage													biological_process											owl:Class	
GO:0006166	biolink:NamedThing	purine ribonucleoside salvage	Any process which produces a purine nucleoside from derivatives of it, without de novo synthesis.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:P121-PWY									biological_process											owl:Class	
GO:0033766	biolink:NamedThing	2-hydroxyquinoline 8-monooxygenase activity	Catalysis of the reaction: H(+) + NADH + O(2) + quinolin-2-ol = H(2)O + NAD(+) + quinoline-2,8-diol.	tmpzr1t_l9r_go_relaxed.owl	quinolin-2(1H)-one,NADH:oxygen oxidoreductase (8-oxygenating) activity|2-oxo-1,2-dihydroquinoline 8-monooxygenase activity				EC:1.14.13.61|RHEA:22080|MetaCyc:1.14.13.61-RXN|KEGG_REACTION:R05158									molecular_function											owl:Class	
GO:0102560	biolink:NamedThing	5-phospho-alpha-D-ribose 1,2-cyclic phosphate 1-phosphohydrolase activity	Catalysis of the reaction: 5-phosphonato-alpha-D-ribose cyclic-1,2-phosphate + H2O <=> D-ribofuranose 2,5-bisphosphate + H+.	tmpzr1t_l9r_go_relaxed.owl	phosphoribosyl 1,2-cyclic phosphate 1,2-diphosphodiesterase				RHEA:41612|MetaCyc:RXN-14995|EC:3.1.4.57									molecular_function											owl:Class	
GO:0044672	biolink:NamedThing	acetyl-CoA decarbonylase/synthase-carbon monoxide dehydrogenase complex	A multifunctional enzyme complex composed of five different polypeptides that catalyzes the decarbonylation of acetyl-CoA, cleaves the C-C and C-S bonds in the acetyl moiety of acetyl-CoA, oxidizes the carbonyl group to CO2 and transfers the methyl group to tetrahydrosarcinapterin. These reactions are important for methanogenesis.	tmpzr1t_l9r_go_relaxed.owl	CODH|carbon-monoxide:(acceptor) oxidoreductase complex|CODH/ACS complex|CO dehydrogenase/acetyl-CoA synthase complex|carbon monoxide dehydrogenase|CO dehydrogenase complex							jl	2012-08-08T16:06:03Z					cellular_component											owl:Class	
GO:0090517	biolink:NamedThing	L-lysine transmembrane import into vacuole	The directed movement of L-lysine into the vacuole across the vacuolar membrane.	tmpzr1t_l9r_go_relaxed.owl	vacuolar lysine import|lysine transmembrane import into vacuole							tb	2012-09-24T14:12:46Z			GO:0090456		biological_process											owl:Class	
GO:0106044	biolink:NamedThing	guanine deglycation	The removal of a sugar or dicarbonyl from a glycated guanine.	tmpzr1t_l9r_go_relaxed.owl								hjd	2017-08-01T18:15:28Z					biological_process											owl:Class	
GO:0015296	biolink:NamedThing	anion:cation symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: anion(out) + cation(out) = anion(in) + cation(in).	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1902285	biolink:NamedThing	semaphorin-plexin signaling pathway involved in neuron projection guidance	Any semaphorin-plexin signaling pathway that is involved in neuron projection guidance.	tmpzr1t_l9r_go_relaxed.owl	semaphorin-plexin signaling pathway involved in neuron protrusion guidance|semaphorin-plexin signalling pathway involved in neuronal cell projection guidance|semaphorin-plexin signaling pathway involved in neuronal cell projection guidance|semaphorin-plexin signalling pathway involved in neuron protrusion guidance|semaphorin-plexin signalling pathway involved in neuron projection guidance|semaphorin-plexin signaling pathway involved in neurite guidance|semaphorin-plexin signaling pathway involved in neuron process guidance|semaphorin-plexin signalling pathway involved in neurite guidance|semaphorin-plexin signalling pathway involved in neuron process guidance							pr	2013-07-08T16:06:46Z					biological_process											owl:Class	
GO:0075504	biolink:NamedThing	macropinosomal membrane permeabilization involved in viral entry into host cell	Induction of macropinosome membrane permeabilization triggered by an interaction between the host membrane and a membrane-penetration protein associated with the capsid. Occurs after internalization of the virus in a macropinosome, and results in release of the viral contents from the macropinosome into the host cell cytoplasm.	tmpzr1t_l9r_go_relaxed.owl	viral entry into host cell via macropinocytosis followed by macropinosomal membrane permeabilization							jl	2010-06-02T02:48:36Z					biological_process											owl:Class	
GO:0039665	biolink:NamedThing	permeabilization of host organelle membrane involved in viral entry into host cell	Induction of organellar membrane permeabilization triggered by an interaction between the host membrane and a membrane-penetration protein associated with a viral capsid. Results in release of the virus contents from an organelle into the host cell cytoplasm.	tmpzr1t_l9r_go_relaxed.owl	viral membrane-penetration protein|viral penetration via host endosomal membrane disruption by virus|viral penetration via permeabilization of host organellar membrane|viral entry into host cell via permeabilization of host organelle membrane|viral penetration via perforation of host organellar membrane by virus				VZ:985			bf	2013-08-29T11:57:21Z					biological_process											owl:Class	
GO:0060262	biolink:NamedThing	negative regulation of N-terminal protein palmitoylation	Any process that decreases the rate frequency or extent of the covalent attachment of a palmitoyl group to the N-terminal amino acid residue of a protein.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0140102	biolink:NamedThing	catalytic activity, acting on a rRNA	Catalytic activity that acts to modify a ribosomal RNA.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/14225						pg	2017-09-15T19:00:57Z					molecular_function											owl:Class	
GO:0070064	biolink:NamedThing	proline-rich region binding	Binding to a proline-rich region, i.e. a region that contains a high proportion of proline residues, in a protein.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0071902	biolink:NamedThing	positive regulation of protein serine/threonine kinase activity	Any process that increases the rate, frequency, or extent of protein serine/threonine kinase activity.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-09-15T03:09:57Z					biological_process											owl:Class	
GO:0044308	biolink:NamedThing	axonal spine	A spine that originates from the axon, usually from the initial segment.	tmpzr1t_l9r_go_relaxed.owl	axon spine				NIF_Subcellular:sao18239917			jl	2010-02-05T04:22:13Z					cellular_component											owl:Class	
GO:1901186	biolink:NamedThing	positive regulation of ERBB signaling pathway	Any process that activates or increases the frequency, rate or extent of ERBB signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	upregulation of ErbB signaling|positive regulation of EGF receptor family signaling pathway|up regulation of ERBB signalling pathway|activation of ERBB signalling pathway|up regulation of ErbB signaling|up regulation of EGF receptor family signaling pathway|upregulation of EGF receptor family signaling pathway|positive regulation of ERBB signalling pathway|activation of ErbB signaling|upregulation of EGFR family signaling pathway|up-regulation of ERBB signaling pathway|up regulation of EGFR family signaling pathway|up regulation of ERBB signaling pathway|activation of EGFR family signaling pathway|positive regulation of ErbB signaling|up-regulation of ErbB signaling|up-regulation of EGFR family signaling pathway|positive regulation of EGFR family signaling pathway|activation of ERBB signaling pathway|up-regulation of ERBB signalling pathway|activation of EGF receptor family signaling pathway|up-regulation of EGF receptor family signaling pathway|upregulation of ERBB signalling pathway|upregulation of ERBB signaling pathway							rl	2012-07-24T07:37:43Z					biological_process											owl:Class	
GO:0090106	biolink:NamedThing	pancreatic E cell fate commitment	The commitment of a cell to a pancreatic E cell fate and its capacity to differentiate into a pancreatic E cell.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-11-18T11:51:41Z					biological_process											owl:Class	
GO:0044161	biolink:NamedThing	host cell cytoplasmic vesicle	A vesicle formed of membrane or protein, found in the cytoplasm of a host cell.	tmpzr1t_l9r_go_relaxed.owl								jl	2009-08-11T04:22:21Z					cellular_component											owl:Class	
GO:0008317	biolink:NamedThing	gurken receptor binding	Binding to a gurken growth factor receptor.	tmpzr1t_l9r_go_relaxed.owl	gurken receptor ligand													molecular_function											owl:Class	
GO:0005154	biolink:NamedThing	epidermal growth factor receptor binding	Binding to an epidermal growth factor receptor.	tmpzr1t_l9r_go_relaxed.owl	epidermal growth factor receptor ligand|EGF receptor binding|transforming growth factor alpha|transforming growth factor alpha receptor binding|epidermal growth factor|EGF receptor ligand|EGF|TGF-alpha receptor binding|EGFR binding|transforming growth factor alpha receptor ligand|TGFalpha receptor binding											GO:0008185		molecular_function											owl:Class	
GO:0044655	biolink:NamedThing	phagosome reneutralization	Any process that increases the pH of the phagosome, measured by the concentration of the hydrogen ion, as part of the process of phagosome maturation.	tmpzr1t_l9r_go_relaxed.owl	phagosome pH elevation|phagosomal reneutralization							jl	2012-07-26T04:21:14Z					biological_process											owl:Class	
GO:0051454	biolink:NamedThing	intracellular pH elevation	Any process that increases the internal pH of a cell, measured by the concentration of the hydrogen ion.	tmpzr1t_l9r_go_relaxed.owl	intracellular alkalinization|cell pH elevation|cellular alkalinization|elevation of cellular pH|pH elevation in cell													biological_process											owl:Class	
GO:0000001	biolink:NamedThing	mitochondrion inheritance	The distribution of mitochondria, including the mitochondrial genome, into daughter cells after mitosis or meiosis, mediated by interactions between mitochondria and the cytoskeleton.	tmpzr1t_l9r_go_relaxed.owl	mitochondrial inheritance													biological_process											owl:Class	
GO:0048311	biolink:NamedThing	mitochondrion distribution	Any process that establishes the spatial arrangement of mitochondria between and within cells.	tmpzr1t_l9r_go_relaxed.owl	positioning of mitochondria|distribution of mitochondria|mitochondrial distribution													biological_process											owl:Class	
GO:0035507	biolink:NamedThing	regulation of myosin-light-chain-phosphatase activity	Any process that modulates the frequency, rate or extent of myosin-light-chain-phosphatase activity.	tmpzr1t_l9r_go_relaxed.owl								bf	2010-04-30T10:53:38Z					biological_process											owl:Class	
GO:0004739	biolink:NamedThing	pyruvate dehydrogenase (acetyl-transferring) activity	Catalysis of the reaction: pyruvate + lipoamide = S-acetyldihydrolipoamide + CO2.	tmpzr1t_l9r_go_relaxed.owl	MtPDC (mitochondrial pyruvate dehydogenase complex) activity|pyruvate:lipoamide 2-oxidoreductase (decarboxylating and acceptor-acetylating) activity|pyruvate dehydrogenase (lipoamide) activity|PDH|pyruvate dehydrogenase complex activity|pyruvate:dihydrolipoyllysine-residue acetyltransferase-lipoyllysine 2-oxidoreductase (decarboxylating, acceptor-acetylating)				RHEA:19189|EC:1.2.4.1									molecular_function											owl:Class	
GO:0071689	biolink:NamedThing	muscle thin filament assembly	The aggregation, arrangement and bonding together of proteins to form the actin-based thin filaments of myofibrils in striated muscle.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-02-25T03:54:06Z					biological_process											owl:Class	
GO:0015645	biolink:NamedThing	fatty acid ligase activity	Catalysis of the ligation of a fatty acid to an acceptor, coupled to the hydrolysis of ATP.	tmpzr1t_l9r_go_relaxed.owl	fatty acyl-coenzyme A synthetase activity|fatty-acid ligase activity|fatty acid CoA ligase activity													molecular_function											owl:Class	
GO:0045481	biolink:NamedThing	6-endo-hydroxycineole dehydrogenase activity	Catalysis of the reaction: 6-endo-hydroxycineole + NAD(+) = 6-oxocineole + H(+) + NADH.	tmpzr1t_l9r_go_relaxed.owl	6-endo-hydroxycineole:NAD+ 6-oxidoreductase activity				RHEA:11736|KEGG_REACTION:R02994|MetaCyc:6-ENDO-HYDROXYCINEOLE-DEHYDROGENASE-RXN|EC:1.1.1.241									molecular_function											owl:Class	
GO:0090700	biolink:NamedThing	maintenance of plant organ identity	The process in which the identity of a plant organ is maintained. Identity is considered to be the aggregate of characteristics by which a structure is recognized.	tmpzr1t_l9r_go_relaxed.owl								tb	2016-08-29T15:01:08Z					biological_process											owl:Class	
GO:0120028	biolink:NamedThing	negative regulation of osmosensory signaling pathway	Any process that stops, prevents or reduces the frequency, rate or extent of osmosensory signaling pathway.	tmpzr1t_l9r_go_relaxed.owl								krc	2017-03-31T15:00:28Z					biological_process											owl:Class	
GO:0070307	biolink:NamedThing	lens fiber cell development	The process whose specific outcome is the progression of a lens fiber cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a lens fiber cell fate. A lens fiber cell is any of the elongated, tightly packed cells that make up the bulk of the mature lens in a camera-type eye.	tmpzr1t_l9r_go_relaxed.owl	lens fibre cell development													biological_process											owl:Class	
GO:0016533	biolink:NamedThing	protein kinase 5 complex	A protein complex that has protein serine/threonine kinase activity; in mammals composed of catalytic subunit CDK5 and regulatory subunits CDK5R1 or CDK5R2. Contrary to its gene symbol, CDK5 is not cyclin-dependent.	tmpzr1t_l9r_go_relaxed.owl	cyclin-dependent protein kinase 5 holoenzyme complex													cellular_component											owl:Class	
GO:0052703	biolink:NamedThing	cellular modified histidine biosynthetic process	The chemical reactions and pathways resulting in the formation of compounds derived from histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid.	tmpzr1t_l9r_go_relaxed.owl	cellular modified histidine formation|cellular histidine derivative anabolism|cellular histidine derivative biosynthesis|histidine derivative biosynthetic process|cellular histidine derivative biosynthetic process|cellular modified histidine synthesis|cellular histidine derivative synthesis|cellular histidine derivative formation|cellular modified histidine biosynthesis|cellular modified histidine anabolism							ai	2011-08-01T03:49:39Z					biological_process											owl:Class	
GO:0070451	biolink:NamedThing	cell hair	A long, thin cell projection that contains F-actin and tubulin, with microtubules centrally located and F-actin peripherally located.	tmpzr1t_l9r_go_relaxed.owl	non-sensory hair|imaginal disc-derived wing hair				Wikipedia:Membrane_nanotube									cellular_component											owl:Class	
GO:0071094	biolink:NamedThing	alpha6-beta4 integrin-CD9 complex	A protein complex that consists of an alpha6-beta4 integrin complex bound to the cell surface protein CD9.	tmpzr1t_l9r_go_relaxed.owl	ITGA6-ITGB4-CD9 complex							mah	2009-11-06T04:47:44Z					cellular_component											owl:Class	
GO:0001518	biolink:NamedThing	voltage-gated sodium channel complex	A sodium channel in a cell membrane whose opening is governed by the membrane potential.	tmpzr1t_l9r_go_relaxed.owl	voltage-dependent sodium channel complex|voltage gated sodium channel complex|voltage-sensitive sodium channel complex				NIF_Subcellular:sao785001660									cellular_component											owl:Class	
GO:0002084	biolink:NamedThing	protein depalmitoylation	The removal of palymitoyl groups from a lipoprotein.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0046253	biolink:NamedThing	anaerobic toluene biosynthetic process	The chemical reactions and pathways resulting in the formation of toluene, a volatile monoaromatic hydrocarbon found in crude petroleum and petroleum products, in the absence of oxygen.	tmpzr1t_l9r_go_relaxed.owl	anaerobic toluene synthesis|anaerobic toluene formation|anaerobic toluene biosynthesis|anaerobic toluene anabolism					This term was reinstated from obsolete.								biological_process											owl:Class	
GO:0018971	biolink:NamedThing	anaerobic toluene metabolic process	The chemical reactions and pathways involving toluene, a volatile monoaromatic hydrocarbon found in crude petroleum and petroleum products, that occur in the absence of oxygen.	tmpzr1t_l9r_go_relaxed.owl	anaerobic toluene metabolism				UM-BBD_pathwayID:tol2									biological_process											owl:Class	
GO:0048838	biolink:NamedThing	release of seed from dormancy	The process in which the dormant state is broken in a seed. Dormancy is characterized by a suspension of physiological activity that can be reactivated upon release.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0071833	biolink:NamedThing	peptide pheromone export involved in positive regulation of conjugation with cellular fusion	The directed movement of a peptide pheromone out of a cell by a secretion or export pathway used solely for the export of peptide pheromones that contributes to a conjugation process that results in the union of cellular and genetic information from compatible mating types.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-09-09T11:09:43Z					biological_process											owl:Class	
GO:1901157	biolink:NamedThing	neomycin catabolic process	The chemical reactions and pathways resulting in the breakdown of neomycin.	tmpzr1t_l9r_go_relaxed.owl	neomycin catabolism|neomycin degradation|neomycin breakdown							yaf	2012-07-17T04:28:20Z					biological_process											owl:Class	
GO:0061530	biolink:NamedThing	aspartate secretion, neurotransmission	The regulated release of aspartate by a cell in which the aspartate acts as a neurotransmitter.	tmpzr1t_l9r_go_relaxed.owl								dph	2013-06-21T15:50:10Z					biological_process											owl:Class	
GO:0008553	biolink:NamedThing	P-type proton-exporting transporter activity	Enables the transfer of protons from one side of a membrane to the other according to the reaction: ATP + H2O + H+(in) -> ADP + phosphate + H+(out). These transporters use a phosphorylative mechanism, which have a phosphorylated intermediate state during the ion transport cycle.	tmpzr1t_l9r_go_relaxed.owl	H+-transporting ATPase|proton-translocating ATPase activity|hydrogen-exporting ATPase activity|hydrogen exporting ATPase activity, phosphorylative mechanism|proton transport ATPase activity|hydrogen-exporting ATPase activity, phosphorylative mechanism|H+-exporting ATPase activity|P-type H(+)-exporting ATPase activity|hydrogen-/sodium-translocating ATPase activity|H(+)-transporting ATPase activity|proton-exporting ATPase activity|proton-exporting ATPase activity, phosphorylative mechanism|proton-transporting ATPase activity				RHEA:20852|MetaCyc:3.6.3.6-RXN|EC:7.1.2.1			bf	2013-09-30T16:56:16Z			GO:0036442		molecular_function											owl:Class	
GO:0010165	biolink:NamedThing	response to X-ray	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of X-ray radiation. An X-ray is a form of electromagnetic radiation with a wavelength in the range of 10 nanometers to 100 picometers (corresponding to frequencies in the range 30 PHz to 3 EHz).	tmpzr1t_l9r_go_relaxed.owl	response to X-ray radiation stimulus													biological_process											owl:Class	
GO:0086091	biolink:NamedThing	regulation of heart rate by cardiac conduction	A cardiac conduction process that modulates the frequency or rate of heart contraction.	tmpzr1t_l9r_go_relaxed.owl								dph	2011-11-29T01:04:19Z					biological_process											owl:Class	
GO:0140642	biolink:NamedThing	meiotic spindle formation (spindle phase two)	The spindle organization process in which the spindle is maintained at a constant length during meiotic metaphase.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/21349						pg	2021-05-11T08:18:16Z					biological_process											owl:Class	
GO:0043683	biolink:NamedThing	type IV pilus assembly	The assembly from its constituent parts of a type IV pilus.	tmpzr1t_l9r_go_relaxed.owl	type IV fimbriae biogenesis|type IV pilus biogenesis|type IV fimbrium assembly|type IV fimbria assembly|type IV fimbrial assembly|type IV fimbriae assembly|type IV fimbrium biogenesis|type IV fimbria biogenesis|type IV fimbrial biogenesis	https://github.com/geneontology/go-ontology/issues/14579												biological_process											owl:Class	
GO:0070405	biolink:NamedThing	ammonium ion binding	Binding to ammonium ions (NH4+).	tmpzr1t_l9r_go_relaxed.owl	ammonium binding													molecular_function											owl:Class	
GO:0018651	biolink:NamedThing	toluene-4-sulfonate monooxygenase activity	Catalysis of the reaction: toluene-4-sulfonate + 1/2 O2 + H+ = HSO3(-) + 4-hydroxytoluene.	tmpzr1t_l9r_go_relaxed.owl	toluene-4-sulphonate monooxygenase activity				UM-BBD_reactionID:r0296|EC:1.14.13.-									molecular_function											owl:Class	
GO:0021836	biolink:NamedThing	chemorepulsion involved in postnatal olfactory bulb interneuron migration	The creation and reception of signals that repel olfactory bulb interneurons from the subventricular zone as a component process in tangential migration.	tmpzr1t_l9r_go_relaxed.owl	negative chemotaxis involved in postnatal olfactory bulb interneuron migration													biological_process											owl:Class	
GO:1902052	biolink:NamedThing	(25S)-Delta(7)-dafachronate binding	Binding to (25S)-Delta(7)-dafachronate.	tmpzr1t_l9r_go_relaxed.owl								ab	2013-04-11T08:34:38Z					molecular_function											owl:Class	
GO:0070728	biolink:NamedThing	leucine binding	Binding to 2-amino-4-methylpentanoic acid.	tmpzr1t_l9r_go_relaxed.owl	Leu binding							mah	2009-06-17T03:16:30Z					molecular_function											owl:Class	
GO:0060216	biolink:NamedThing	definitive hemopoiesis	A second wave of blood cell production that, in vertebrates, generates long-term hemopoietic stem cells that continously provide erythroid, myeloid and lymphoid lineages throughout adulthood.	tmpzr1t_l9r_go_relaxed.owl	definitive hematopoiesis|definitive haemopoiesis|definitive haematopoiesis													biological_process											owl:Class	
GO:0120283	biolink:NamedThing	protein serine/threonine kinase binding	Binding to a protein serine/threonine kinase.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/15218						krc	2020-11-17T16:26:36Z					molecular_function											owl:Class	
GO:0042864	biolink:NamedThing	pyochelin biosynthetic process	The chemical reactions and pathways resulting in the formation of the siderochrome pyochelin (2-(2-o-hydroxyphenyl-2-thiazolin-4-yl)-3-methylthiazolidine-4-carboxylic acid).	tmpzr1t_l9r_go_relaxed.owl	pyochelin biosynthetic process, peptide modification|pyochelin synthesis|pyochelin formation|pyochelin biosynthetic process, peptide formation|pyochelin biosynthesis|pyochelin anabolism											GO:0031188|GO:0031187		biological_process											owl:Class	
GO:0002902	biolink:NamedThing	regulation of B cell apoptotic process	Any process that modulates the frequency, rate, or extent of B cell apoptotic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of B cell apoptosis													biological_process											owl:Class	
GO:0004961	biolink:NamedThing	thromboxane A2 receptor activity	Combining with thromboxane A2 (TXA(2)) and transmitting the signal across the membrane to activate an associated G-protein.	tmpzr1t_l9r_go_relaxed.owl	TXA(2) receptor activity|TXA2 receptor activity													molecular_function											owl:Class	
GO:0042210	biolink:NamedThing	octamethylcyclotetrasiloxane catabolic process to dimethylsilanediol	The anaerobic chemical reactions and pathways resulting in the breakdown of octamethylcyclotetrasiloxane into dimethylsilanediol. The former is a tetramer of the latter.	tmpzr1t_l9r_go_relaxed.owl	catabolism of octamethylcyclotetrasiloxane to DMSD|octamethylcyclotetrasiloxane degradation to dimethylsilanediol|catabolic process of octamethylcyclotetrasiloxane to DMSD|octamethylcyclotetrasiloxane breakdown to dimethylsilanediol				UM-BBD_pathwayID:osi									biological_process											owl:Class	
GO:0046454	biolink:NamedThing	dimethylsilanediol metabolic process	The chemical reactions and pathways involving dimethylsilanediol, the smallest member of the dialkylsilanediols. Dimethylsilanediol is the monomer of polydimethylsiloxane, a compound which can be found in a wide range of industrial and consumer products.	tmpzr1t_l9r_go_relaxed.owl	dimethylsilanediol metabolism													biological_process											owl:Class	
GO:0033729	biolink:NamedThing	anthocyanidin reductase activity	Catalysis of the reaction: a flavan-3-ol + 2 NAD(P)+ = an anthocyanidin + 2 NAD(P)H + H+.	tmpzr1t_l9r_go_relaxed.owl	flavan-3-ol:NAD(P)+ oxidoreductase activity|MtANR|ANR|AtANR				MetaCyc:1.3.1.77-RXN|EC:1.3.1.77									molecular_function											owl:Class	
GO:0060867	biolink:NamedThing	fruit abscission	The controlled shedding of a fruit.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-08-12T06:35:28Z					biological_process											owl:Class	
GO:0020011	biolink:NamedThing	apicoplast	The plastid organelle found in apicomplexans.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Apicoplast									cellular_component											owl:Class	
GO:0018376	biolink:NamedThing	peptidyl-asparagine hydroxylation to form L-erythro-beta-hydroxyasparagine	The hydroxylation of peptidyl-asparagine to form peptidyl-L-erythro-beta-hydroxyasparagine; catalyzed by peptide-aspartate beta-dioxygenase (EC:1.14.11.16).	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0026	See also the molecular function term 'peptide-aspartate beta-dioxygenase activity ; GO:0004597'.								biological_process											owl:Class	
GO:0050690	biolink:NamedThing	regulation of defense response to virus by virus	Any viral process that modulates the frequency, rate, or extent of the antiviral response of the host cell or organism.	tmpzr1t_l9r_go_relaxed.owl	regulation of antiviral response by virus|viral regulation of antiviral response|regulation by virus of antiviral response													biological_process											owl:Class	
GO:0060513	biolink:NamedThing	prostatic bud formation	The morphogenetic process in which a region of the fetal urogenital sinus epithelium is specified to become the prostate, resulting in prostate bud outgrowth.	tmpzr1t_l9r_go_relaxed.owl	prostate gland formation|primary prostate bud formation|prostate ductal budding													biological_process											owl:Class	
GO:0061827	biolink:NamedThing	sperm head	The part of the late spermatid or spermatozoon that contains the nucleus and acrosome.	tmpzr1t_l9r_go_relaxed.owl								dph	2017-01-15T10:39:00Z					cellular_component											owl:Class	
GO:0050001	biolink:NamedThing	D-glutaminase activity	Catalysis of the reaction: H2O + L-glutamine = NH3 + D-glutamate.	tmpzr1t_l9r_go_relaxed.owl	D-glutamine amidohydrolase activity				RHEA:22840|MetaCyc:D-GLUTAMINASE-RXN|EC:3.5.1.35									molecular_function											owl:Class	
GO:0045303	biolink:NamedThing	diaminobutyrate-2-oxoglutarate transaminase activity	Catalysis of the reaction: 2-oxoglutarate + L-2,4-diaminobutyrate = L-aspartate 4-semialdehyde + L-glutamate.	tmpzr1t_l9r_go_relaxed.owl	DAB aminotransferase activity|EctB|diaminobutyrate transaminase activity|diaminibutyric acid aminotransferase activity|L-2,4-diaminobutyrate:2-oxoglutarate 4-aminotransferase activity|L-2,4-diaminobutanoate:2-oxoglutarate 4-aminotransferase activity|2,4-diaminobutyrate 4-aminotransferase activity|L-2,4-diaminobutyrate:2-ketoglutarate 4-aminotransferase activity|diaminobutyrate--2-oxoglutarate aminotransferase activity|DABA aminotransferase activity				EC:2.6.1.76|KEGG_REACTION:R06977|RHEA:11160|MetaCyc:R101-RXN									molecular_function											owl:Class	
GO:0000124	biolink:NamedThing	SAGA complex	A SAGA-type histone acetyltransferase complex that deubiquitinates H2A and/or H2B. This complex is organized into several functional submodules: a structural core including the activator binding module and consisting of ADA1 or a homolog, members of the SPT and TAF protein families as well as promotor recruitment factor TRRAP/TRA1, a histone acetyltransferase (HAT) module consisting of GCN5/KAT2A or PCAF/KAT2B, ADA2, ADA3/NGG1, and SGF29 or homologues thereof, a histone deubiquitinase (DUB) module consisting of ATXN7/SGF73, ATXN7L3/SGF11, ENY2/SUS1 and USP22/UBP8 or homologues thereof, and in some taxa a splicing module consisting of SF3B3 and SF3B5 or homologues thereof (not in fungi). In budding yeast also contains Spt8 which distinguishes it from SAGA-like (SLIK) complex (GO:0046695).	tmpzr1t_l9r_go_relaxed.owl	STAGA coactivator complex|SPT3-TAF9-GCN5 acetylase complex|PCAF histone acetylase-associated complex|Spt-Ada-Gcn5-acetyltransferase complex|STAGA complex|PCAF complex|SPT3-TAF9-PCAF acetylase complex											GO:0000125|GO:0030914		cellular_component											owl:Class	
GO:0070452	biolink:NamedThing	positive regulation of ergosterol biosynthetic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of ergosterol.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of ergosterol anabolism|up-regulation of ergosterol biosynthetic process|activation of ergosterol biosynthetic process|positive regulation of ergosterol formation|positive regulation of ergosterol synthesis|upregulation of ergosterol biosynthetic process|up regulation of ergosterol biosynthetic process|positive regulation of ergosterol biosynthesis|stimulation of ergosterol biosynthetic process													biological_process											owl:Class	
GO:0046721	biolink:NamedThing	formic acid secretion	The controlled release of formic acid, HCOOH, by a cell or a tissue.	tmpzr1t_l9r_go_relaxed.owl	formate secretion													biological_process											owl:Class	
GO:0033811	biolink:NamedThing	flavonol-3-O-triglucoside O-coumaroyltransferase activity	Catalysis of the reaction: 4-coumaroyl-CoA + a flavonol 3-O-[beta-D-glucosyl-(1->2)-beta-D-glucosyl-(1->2)-beta-D-glucoside] = CoA + a flavonol 3-O-[6-(4-coumaroyl)-beta-D-glucosyl-(1->2)-beta-D-glucosyl-(1->2)-beta-D-glucoside].	tmpzr1t_l9r_go_relaxed.owl	4-coumaroyl-CoA:flavonol-3-O-[beta-D-glucosyl-(1->2)-beta-D-glucosyl-(1->2)-beta-D-glucoside] 6'''-O-4-coumaroyltransferase activity				EC:2.3.1.173|MetaCyc:2.3.1.173-RXN|RHEA:22160									molecular_function											owl:Class	
GO:0035633	biolink:NamedThing	maintenance of blood-brain barrier	Maintaining the structure and function of the blood-brain barrier, thus ensuring specific regulated transport of substances (e.g. macromolecules, small molecules, ions) into the brain, and out of the brain into the blood circulation.	tmpzr1t_l9r_go_relaxed.owl	maintenance of BBB|maintenance of blood/brain barrier					Homeostasis and maintenance processes are regulatory processes, therefore, regulation child terms, such as: regulation of maintenance of blood-brain barrier, should not exist for these terms.  Instead, for capturing regulation at the blood-brain barrier, consider using the part_of child term: regulation of blood-brain barrier permeability.		bf	2011-01-07T10:33:11Z					biological_process											owl:Class	
GO:1904257	biolink:NamedThing	zinc ion import into Golgi apparatus	The directed import of zinc(2+) from the cytosol across the Golgi membrane into the Golgi apparatus.	tmpzr1t_l9r_go_relaxed.owl	zinc II ion import across Golgi membrane|zinc ion import into Golgi membrane|zinc ion import across Golgi membrane|zinc(2+) import across Golgi membrane							tb	2015-05-20T19:56:18Z					biological_process											owl:Class	
GO:0071830	biolink:NamedThing	triglyceride-rich lipoprotein particle clearance	The process in which a triglyceride-rich lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-09-08T11:23:55Z					biological_process											owl:Class	
GO:0090375	biolink:NamedThing	negative regulation of transcription from RNA polymerase II promoter in response to iron ion starvation	Any process that decreases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of deprivation of iron ions.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of transcription from RNA polymerase II promoter in response to iron deficiency							tb	2010-09-01T01:22:23Z					biological_process											owl:Class	
GO:0102547	biolink:NamedThing	glucosylglycerate hydrolase activity	Catalysis of the reaction: H2O + 2-O-(alpha-D-glucopyranosyl)-D-glycerate <=> alpha-D-glucose + D-glycerate.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-14901|RHEA:32059									molecular_function											owl:Class	
GO:0021855	biolink:NamedThing	hypothalamus cell migration	The directed movement of a cell into the hypothalamus region of the forebrain.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0032526	biolink:NamedThing	response to retinoic acid	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a retinoic acid stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to vitamin A acid													biological_process											owl:Class	
GO:0097738	biolink:NamedThing	substrate mycelium formation	The process by which, in some fungal species, hyphae grow as a network of invasive thread-like filaments formed from chains of attached cells within a solid or semi-solid substrate.	tmpzr1t_l9r_go_relaxed.owl								pr	2016-10-18T16:21:05Z					biological_process											owl:Class	
GO:0009428	biolink:NamedThing	bacterial-type flagellum basal body, distal rod, P ring	One of the rings of the bacterial-type flagellar basal body; anchors the basal body to the peptidoglycan layer.	tmpzr1t_l9r_go_relaxed.owl	flagellar basal body, distal rod, P ring|flagellin-based flagellum basal body, distal rod, P ring													cellular_component											owl:Class	
GO:0045130	biolink:NamedThing	keratan sulfotransferase activity	Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + keratan = adenosine 3',5'-bisphosphate + keratan 6'-sulfate.	tmpzr1t_l9r_go_relaxed.owl	3'-phosphoadenylylsulfate:keratan sulfotransferase activity|keratan sulfate sulfotransferase activity|keratan sulfate Gal-6-sulfotransferase activity|3'-phosphoadenylyl-sulfate:keratan 6'-sulfotransferase activity|keratan sulphotransferase activity|3'-phosphoadenylyl keratan sulfotransferase activity				EC:2.8.2.21|Reactome:R-HSA-2046175|MetaCyc:KERATAN-SULFOTRANSFERASE-RXN									molecular_function											owl:Class	
GO:0007270	biolink:NamedThing	neuron-neuron synaptic transmission	The process of synaptic transmission from a neuron to another neuron across a synapse.	tmpzr1t_l9r_go_relaxed.owl	nerve-nerve synaptic transmission													biological_process											owl:Class	
GO:0050060	biolink:NamedThing	long-chain-alcohol dehydrogenase activity	Catalysis of the reaction: a long-chain alcohol + 2 NAD+ + H2O = a long-chain carboxylate + 2 NADH.	tmpzr1t_l9r_go_relaxed.owl	long-chain alcohol dehydrogenase activity|fatty alcohol oxidoreductase activity|long-chain-alcohol:NAD+ oxidoreductase activity				EC:1.1.1.192|MetaCyc:LONG-CHAIN-ALCOHOL-DEHYDROGENASE-RXN|RHEA:17977									molecular_function											owl:Class	
GO:1900449	biolink:NamedThing	regulation of glutamate receptor signaling pathway	Any process that modulates the frequency, rate or extent of glutamate receptor signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	regulation of glutamate signaling pathway|regulation of glutamate signalling pathway							rl	2012-04-27T03:45:43Z					biological_process											owl:Class	
GO:0046305	biolink:NamedThing	alkanesulfonate biosynthetic process	The chemical reactions and pathways resulting in the formation of alkanesulfonates, the anion of alkanesulfonic acids, sulfonic acid derivatives containing an aliphatic hydrocarbon group.	tmpzr1t_l9r_go_relaxed.owl	alkanesulphonate biosynthetic process|alkanesulphonate biosynthesis|alkanesulfonate formation|alkanesulfonate synthesis|alkanesulfonate anabolism|alkanesulfonate biosynthesis													biological_process											owl:Class	
GO:0000255	biolink:NamedThing	allantoin metabolic process	The chemical reactions and pathways involving allantoin, (2,5-dioxo-4-imidazolidinyl)urea, an intermediate or end product of purine catabolism.	tmpzr1t_l9r_go_relaxed.owl	allantoin metabolism													biological_process											owl:Class	
GO:0060582	biolink:NamedThing	cell fate determination involved in pattern specification	A process involved in commitment of a cell to a fate in a developmental field. Once determination has taken place, a cell becomes committed to differentiate down a particular pathway regardless of its environment.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-05-07T12:48:08Z					biological_process											owl:Class	
GO:0098613	biolink:NamedThing	methaneselenol methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + methaneselenol => S-adenosyl-L-homocysteine + dimethyl selenide.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-2408541									molecular_function											owl:Class	
GO:1904074	biolink:NamedThing	negative regulation of trophectodermal cell proliferation	Any process that stops, prevents or reduces the frequency, rate or extent of trophectodermal cell proliferation.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of trophectodermal cell proliferation|down-regulation of trophectoderm cell proliferation|downregulation of trophectoderm cell proliferation|inhibition of trophectodermal cell proliferation|down regulation of trophectodermal cell proliferation|downregulation of trophectodermal cell proliferation|inhibition of trophectoderm cell proliferation|negative regulation of trophectoderm cell proliferation|down regulation of trophectoderm cell proliferation							tb	2015-03-20T16:56:02Z					biological_process											owl:Class	
GO:1903517	biolink:NamedThing	negative regulation of single strand break repair	Any process that stops, prevents or reduces the frequency, rate or extent of single strand break repair.	tmpzr1t_l9r_go_relaxed.owl	down regulation of single strand break repair|downregulation of single strand break repair|inhibition of single strand break repair|down-regulation of single strand break repair							rl	2014-10-06T10:59:01Z					biological_process											owl:Class	
GO:0039706	biolink:NamedThing	co-receptor binding	Binding to a coreceptor. A coreceptor acts in cooperation with a primary receptor to transmit a signal within the cell.	tmpzr1t_l9r_go_relaxed.owl								bf	2013-11-25T14:41:42Z					molecular_function											owl:Class	
GO:0106211	biolink:NamedThing	inositol-5-diphosphate-1,3,4,6-tetrakisphosphate diphosphatase activity	Catalysis of the reaction: 5-diphospho-1D-myo-inositol 1,3,4,6-tetrakisphosphate + H2O = 1D-myo-inositol 1,3,4,5,6-pentakisphosphate + H(+) + phosphate.	tmpzr1t_l9r_go_relaxed.owl	5-diphospho-myo-inositol 1,3,4,6-tetrakisphosphate diphosphatase activity|5-PP-InsP4 activity|5-diphosphoinositol 1,3,4,6-tetrakisphosphate diphosphatase activity				RHEA:59500			hjd	2019-06-06T19:26:38Z					molecular_function											owl:Class	
GO:0052840	biolink:NamedThing	inositol diphosphate tetrakisphosphate diphosphatase activity	Catalysis of the reaction: inositol diphosphate tetrakisphosphate + H2O = inositol 1,3,4,5,6-pentakisphosphate + phosphate.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-1855166|EC:3.6.1.52|MetaCyc:RXN-10963			ai	2011-11-29T04:14:22Z					molecular_function											owl:Class	
GO:1990508	biolink:NamedThing	CKM complex	Cyclin-dependent kinase complex which reversibly associates with the Mediator complex. In Saccharomyces cerevisiae it consists of SSN2, SSN3, SSN8 and SRB8.	tmpzr1t_l9r_go_relaxed.owl	CDK8 kinase module|SRB8/9/10/11 complex|SRB8-SRB11 complex					An example of this is SSN2 in Saccharomyces cerevisiae (P38931) in PMID:12200444 (inferred from physical interaction).		bhm	2014-10-02T10:05:58Z					cellular_component											owl:Class	
GO:0019908	biolink:NamedThing	nuclear cyclin-dependent protein kinase holoenzyme complex	Cyclin-dependent protein kinase (CDK) complex found in the nucleus.	tmpzr1t_l9r_go_relaxed.owl	CDK holoenzyme													cellular_component											owl:Class	
GO:0034270	biolink:NamedThing	Cvt complex	A protein complex that is involved in the Cvt pathway. In budding yeast, the Cvt complex consists of multimers of preApe1p.	tmpzr1t_l9r_go_relaxed.owl	cytoplasm to vacuole targeting complex|cytoplasm-to-vacuole targeting complex													cellular_component											owl:Class	
GO:0050056	biolink:NamedThing	linalool 8-monooxygenase activity	Catalysis of the reaction: AH(2) + linalool + O(2) = (2E)-2,6-dimethylocta-2,7-diene-1,6-diol + A + H(2)O.	tmpzr1t_l9r_go_relaxed.owl	3,7-dimethylocta-1,6-dien-3-ol,hydrogen-donor:oxygen oxidoreductase (8-hydroxylating)				EC:1.14.14.84|MetaCyc:LINALOOL-8-MONOOXYGENASE-RXN|RHEA:32635|KEGG_REACTION:R04366									molecular_function											owl:Class	
GO:0015919	biolink:NamedThing	peroxisomal membrane transport	The directed movement of substances to, from or across the peroxisomal membrane.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0099614	biolink:NamedThing	protein localization to spore cell wall	A process in which a protein is transported, tethered to or otherwise maintained in a spore cell wall.	tmpzr1t_l9r_go_relaxed.owl	protein targeting to spore cell wall													biological_process											owl:Class	
GO:0044478	biolink:NamedThing	envenomation resulting in positive regulation of platelet aggregation in other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant activation, maintenance or an increase in the frequency, rate or extent of platelet aggregation in the bitten organism.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-01-19T02:39:45Z					biological_process											owl:Class	
GO:0033939	biolink:NamedThing	xylan alpha-1,2-glucuronosidase activity	Catalysis of the hydrolysis of alpha-D-(1->2)-(4-O-methyl)glucuronosyl links in the main chain of hardwood xylans.	tmpzr1t_l9r_go_relaxed.owl	1,2-alpha-glucuronidase activity|xylan alpha-D-1,2-(4-O-methyl)glucuronohydrolase activity|alpha-(1->2)-glucuronidase activity				EC:3.2.1.131|MetaCyc:3.2.1.131-RXN									molecular_function											owl:Class	
GO:0061646	biolink:NamedThing	positive regulation of glutamate neurotransmitter secretion in response to membrane depolarization	Any process that activates or increases the frequency, rate or extent of glutamate secretion in response to membrane depolarization, where glutamate acts as a neurotransmitter.	tmpzr1t_l9r_go_relaxed.owl								dph	2014-10-02T14:18:49Z					biological_process											owl:Class	
GO:0045470	biolink:NamedThing	R8 cell-mediated photoreceptor organization	The regionalization process that coordinates the recruitment and organization of other non-R8 photoreceptors by the R8 photoreceptor.	tmpzr1t_l9r_go_relaxed.owl	R8-mediated photoreceptor organisation													biological_process											owl:Class	
GO:0002174	biolink:NamedThing	mammary stem cell proliferation	The expansion of a mammary stem cell population by cell division. Mammary stem cells are a source of cells for growth of the mammary gland during puberty and gestation. These cells can give rise to both the luminal and myoepithelial cell types of the gland, and can regenerate the entire organ.	tmpzr1t_l9r_go_relaxed.owl								hjd	2010-09-14T01:19:45Z					biological_process											owl:Class	
GO:0050760	biolink:NamedThing	negative regulation of thymidylate synthase biosynthetic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of the enzyme thymidylate synthase.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of thymidylate synthase formation|negative regulation of thymidylate synthase anabolism|down regulation of thymidylate synthase biosynthetic process|inhibition of thymidylate synthase biosynthetic process|negative regulation of thymidylate synthase biosynthesis|negative regulation of thymidylate synthase synthesis|downregulation of thymidylate synthase biosynthetic process|down-regulation of thymidylate synthase biosynthetic process													biological_process											owl:Class	
GO:0061211	biolink:NamedThing	mesonephric collecting duct development	The process whose specific outcome is the progression of a collecting duct in the mesonephros over time, from its formation to the mature structure. The collecting duct regulates water, electrolyte and acid-base balance. The collecting duct is the final common path through which urine flows before entering the ureter and then emptying into the bladder.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-08-17T03:25:51Z					biological_process											owl:Class	
GO:0048615	biolink:NamedThing	embryonic anterior midgut (ectodermal) morphogenesis	The process in which the anatomical structures of the anterior midgut (ectodermal) are generated and organized, during the embryonic phase.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0048613	biolink:NamedThing	embryonic ectodermal digestive tract morphogenesis	The process, occurring during the embryonic phase, by which the anatomical structures of the ectodermal digestive tract are generated and organized.	tmpzr1t_l9r_go_relaxed.owl	embryonic ectodermal gut morphogenesis													biological_process											owl:Class	
GO:0001923	biolink:NamedThing	B-1 B cell differentiation	The process in which a hemopoietic stem cell acquires the specialized features of a B-1 B cell. B-1 B cells are a distinct subset of B cells characterized as being CD5 positive, found predominantly in the peritoneum, pleural cavities, and spleen, and enriched for self-reactivity.	tmpzr1t_l9r_go_relaxed.owl	B-1 B cell development|B-1 B lymphocyte differentiation|B-1 B-lymphocyte differentiation|B-1 B-cell differentiation													biological_process											owl:Class	
GO:0070897	biolink:NamedThing	transcription preinitiation complex assembly	The aggregation, arrangement and bonding together of proteins on promoter DNA to form the transcriptional preinitiation complex (PIC), required for transcription.	tmpzr1t_l9r_go_relaxed.owl	bacterial-type RNA polymerase preinitiation complex assembly|DNA-templated transcriptional preinitiation complex assembly|transcription PIC biosynthesis|transcriptional preinitiation complex formation|transcription PIC formation|bacterial-type RNA polymerase transcription PIC formation|DNA-dependent transcriptional preinitiation complex assembly|bacterial-type RNA polymerase transcriptional preinitiation complex formation							mah	2009-09-01T04:33:47Z			GO:0001126		biological_process											owl:Class	
GO:0042717	biolink:NamedThing	plasma membrane-derived chromatophore membrane	The lipid bilayer associated with a plasma membrane-derived chromatophore; surrounds chromatophores that form complete vesicles.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0002080	biolink:NamedThing	acrosomal membrane	The membrane that surrounds the acrosomal lumen. The acrosome is a special type of lysosome in the head of a spermatozoon that contains acid hydrolases and is concerned with the breakdown of the outer membrane of the ovum during fertilization.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:1902900	biolink:NamedThing	gut granule assembly	The aggregation, arrangement and bonding together of a set of components to form a gut granule.	tmpzr1t_l9r_go_relaxed.owl	gut granule biogenesis|gut granule formation							kmv	2014-04-14T14:28:17Z					biological_process											owl:Class	
GO:0150201	biolink:NamedThing	positive regulation of transport across blood-brain barrier	Any process that activates or increases the frequency, rate or extent of transport across blood-brain barrier.	tmpzr1t_l9r_go_relaxed.owl								bc	2020-03-26T19:26:38Z					biological_process											owl:Class	
GO:0075003	biolink:NamedThing	adhesion of symbiont appressorium to host	The attachment of an appressorium of the symbiont to its host via adhesion molecules. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	adhesion of symbiont appressorium to host during symbiotic interaction	https://github.com/geneontology/go-ontology/issues/21505				Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products from the symbiont involved in this process.								biological_process											owl:Class	
GO:0075016	biolink:NamedThing	appressorium formation	The process in which a swollen, flattened portion of a symbiont filament is formed on or near its host organism, to adhere to and for the purpose of penetrating the host surface.	tmpzr1t_l9r_go_relaxed.owl	appressorium formation for entry into host, on or near host|formation of an appressorium by symbiont on or near host|appressorium formation on or near host													biological_process											owl:Class	
GO:0034169	biolink:NamedThing	positive regulation of toll-like receptor 10 signaling pathway	Any process that activates or increases the frequency, rate, or extent of toll-like receptor 10 signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of toll-like receptor 10 signalling pathway|positive regulation of TLR10 signaling pathway													biological_process											owl:Class	
GO:0048931	biolink:NamedThing	posterior lateral line nerve glial cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a glial cell in the posterior lateral line nerve.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:2000699	biolink:NamedThing	fibroblast growth factor receptor signaling pathway involved in ureteric bud formation	The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands that contributes to the formation of the ureteric bud from the Wolffian duct.	tmpzr1t_l9r_go_relaxed.owl	fibroblast growth factor receptor signalling pathway of ureteric bud formation|FGF receptor signaling pathway of ureteric bud formation|FGF receptor signalling pathway of ureteric bud formation|FGFR signaling pathway of ureteric bud formation|fibroblast growth factor receptor signaling pathway of ureteric bud formation							bf	2011-05-16T04:52:14Z					biological_process											owl:Class	
GO:1900824	biolink:NamedThing	positive regulation of ergot alkaloid biosynthetic process	Any process that activates or increases the frequency, rate or extent of ergot alkaloid biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	activation of ergot alkaloid synthesis|upregulation of ergot alkaloid anabolism|up-regulation of ergot alkaloid synthesis|positive regulation of ergot alkaloid synthesis|up regulation of ergot alkaloid biosynthesis|up-regulation of ergot alkaloid biosynthetic process|activation of ergot alkaloid biosynthetic process|up regulation of ergot alkaloid anabolism|positive regulation of ergot alkaloid biosynthesis|up regulation of ergot alkaloid synthesis|up-regulation of ergot alkaloid anabolism|up-regulation of ergot alkaloid biosynthesis|up-regulation of ergot alkaloid formation|activation of ergot alkaloid anabolism|activation of ergot alkaloid biosynthesis|positive regulation of ergot alkaloid anabolism|up regulation of ergot alkaloid formation|upregulation of ergot alkaloid synthesis|upregulation of ergot alkaloid biosynthesis|upregulation of ergot alkaloid biosynthetic process|activation of ergot alkaloid formation|positive regulation of ergot alkaloid formation|up regulation of ergot alkaloid biosynthetic process|upregulation of ergot alkaloid formation							di	2012-06-04T11:13:05Z					biological_process											owl:Class	
GO:0090206	biolink:NamedThing	negative regulation of cholesterol metabolic process	Any process that decreases the rate, frequency, or extent of cholesterol metabolism, the chemical reactions and pathways involving cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-12-23T10:27:37Z					biological_process											owl:Class	
GO:0070081	biolink:NamedThing	clathrin-sculpted monoamine transport vesicle	A clathrin-sculpted lipid bilayer membrane-enclosed vesicle after clathrin release and containing monoamines.	tmpzr1t_l9r_go_relaxed.owl	clathrin sculpted monoamine constitutive secretory pathway transport vesicle|clathrin sculpted monoamine transport vesicle													cellular_component											owl:Class	
GO:0021887	biolink:NamedThing	hypothalamus gonadotrophin-releasing hormone neuron fate commitment	The process in which the developmental fate of a cell becomes restricted such that it will develop into a hypothalamus neuron that releases gonadotrophin-releasing hormone.	tmpzr1t_l9r_go_relaxed.owl	hypothalamus gonadotropin-releasing hormone neuron fate commitment													biological_process											owl:Class	
GO:0021886	biolink:NamedThing	hypothalamus gonadotrophin-releasing hormone neuron differentiation	The process in which a relatively unspecialized cell acquires specialized features of a neuron located in the hypothalamus. These neurons release gonadotrophin-releasing hormone as a neural transmitter.	tmpzr1t_l9r_go_relaxed.owl	hypothalamus gonadotropin-releasing hormone neuron differentiation													biological_process											owl:Class	
GO:1901920	biolink:NamedThing	peptidyl-tyrosine dephosphorylation involved in activation of protein kinase activity	Any peptidyl-tyrosine dephosphorylation that is involved in activation of protein kinase activity.	tmpzr1t_l9r_go_relaxed.owl	peptidyl-tyrosine dephosphorylation involved in protein kinase activation							al	2013-02-15T18:54:53Z					biological_process											owl:Class	
GO:0001875	biolink:NamedThing	lipopolysaccharide immune receptor activity	Combining with a lipopolysaccharide and transmitting the signal across the cell membrane to initiate an innate immune response. Lipopolysaccharides (LPS) are major components of the outer membrane of Gram-negative bacteria, making them prime targets for recognition by the immune system.	tmpzr1t_l9r_go_relaxed.owl	endotoxin receptor activity|LPS receptor activity|lipopolysaccharide receptor activity													molecular_function											owl:Class	
GO:0042407	biolink:NamedThing	cristae formation	The assembly of cristae, the inwards folds of the inner mitochondrial membrane.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0051104	biolink:NamedThing	DNA-dependent DNA replication DNA ligation	The re-formation of a broken phosphodiester bond in the DNA backbone, carried out by DNA ligase, that contributes to DNA-dependent DNA replication.	tmpzr1t_l9r_go_relaxed.owl	DNA ligation during DNA-dependent DNA replication|DNA ligation involved in DNA-dependent DNA replication													biological_process											owl:Class	
GO:0071211	biolink:NamedThing	protein targeting to vacuole involved in autophagy	The process of directing proteins towards the vacuole using signals contained within the protein, occurring as part of autophagy, the process in which cells digest parts of their own cytoplasm.	tmpzr1t_l9r_go_relaxed.owl	protein targeting to autophagosome							mah	2009-11-25T02:25:27Z					biological_process											owl:Class	
GO:1903488	biolink:NamedThing	negative regulation of lactation	Any process that stops, prevents or reduces the frequency, rate or extent of lactation.	tmpzr1t_l9r_go_relaxed.owl	downregulation of lactation|down-regulation of lactation|inhibition of lactation|down regulation of lactation							mr	2014-09-24T14:44:22Z					biological_process											owl:Class	
GO:0007595	biolink:NamedThing	lactation	The regulated release of milk from the mammary glands and the period of time that a mother lactates to feed her young.	tmpzr1t_l9r_go_relaxed.owl	milk secretion				Wikipedia:Lactation									biological_process											owl:Class	
GO:0060979	biolink:NamedThing	vasculogenesis involved in coronary vascular morphogenesis	The differentiation of endothelial cells from progenitor cells that contributes to blood vessel development in the heart, and the de novo formation of blood vessels and tubes.	tmpzr1t_l9r_go_relaxed.owl	vasculogenesis involved in coronary blood vessel morphogenesis|coronary vasculogenesis							dph	2009-10-06T02:19:42Z					biological_process											owl:Class	
GO:0000056	biolink:NamedThing	ribosomal small subunit export from nucleus	The directed movement of a ribosomal small subunit from the nucleus into the cytoplasm.	tmpzr1t_l9r_go_relaxed.owl	ribosomal small subunit export out of nucleus|40S ribosomal subunit export from nucleus|30S ribosomal subunit export from nucleus|ribosomal small subunit-nucleus export|ribosomal small subunit export from cell nucleus|ribosomal small subunit transport from nucleus to cytoplasm											GO:0000058		biological_process											owl:Class	
GO:0090644	biolink:NamedThing	age-related resistance	An innate immune response that is positively correlated with host plant development. As a plant develops, its innate resistance to pathogenic infections increases. The mechanisms involved in age-related resistance differ in nature or in aspects of regulation from the hypersensitive response (HR), systemic acquired resistance (SAR), or induced systemic resistance (ISR).	tmpzr1t_l9r_go_relaxed.owl	flowering-induced resistance|mature seedling resistance|adult seedling resistance|developmental resistance|senescence-induced resistance|ontogenic resistance|ARR							tb	2015-05-19T10:36:38Z					biological_process											owl:Class	
GO:0046606	biolink:NamedThing	negative regulation of centrosome cycle	Any process that stops, prevents, or reduces the frequency, rate or extent of the centrosome cycle.	tmpzr1t_l9r_go_relaxed.owl	inhibition of centrosome cycle|down-regulation of centrosome cycle|down regulation of centrosome cycle|downregulation of centrosome cycle													biological_process											owl:Class	
GO:0030916	biolink:NamedThing	otic vesicle formation	The process resulting in the transition of the otic placode into the otic vesicle, a transient embryonic structure formed during development of the vertebrate inner ear.	tmpzr1t_l9r_go_relaxed.owl	otocyst formation|otocyst biosynthesis													biological_process											owl:Class	
GO:0110124	biolink:NamedThing	positive regulation of myotube cell migration	Any process that activates, maintains or increases the frequency, rate or extent of myotube cell migration.	tmpzr1t_l9r_go_relaxed.owl								kmv	2018-08-22T21:09:38Z					biological_process											owl:Class	
GO:0110122	biolink:NamedThing	myotube cell migration	The orderly movement of a myotube cell from one site to another, often during the development of a multicellular organism. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate, and fuse.	tmpzr1t_l9r_go_relaxed.owl								kmv	2018-08-22T20:58:09Z					biological_process											owl:Class	
GO:0050652	biolink:NamedThing	dermatan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process	The elongation of dermatan sulfate proteoglycan chains by alternate addition of N-acetylhexosamine and GlcUA residues to the GAG-protein linkage region tetrasaccharide of dermatan sulfate.	tmpzr1t_l9r_go_relaxed.owl	dermatan sulfate proteoglycan formation, polysaccharide chain formation|chondroitin sulfate B proteoglycan biosynthesis, polysaccharide chain biosynthesis|dermatan sulfate proteoglycan chain elongation|dermatan sulfate proteoglycan formation, polysaccharide chain biosynthesis|dermatan sulfate proteoglycan synthesis, polysaccharide chain synthesis|dermatan sulfate proteoglycan anabolism, polysaccharide chain anabolism|dermatan sulphate proteoglycan biosynthesis, polysaccharide chain biosynthesis|dermatan sulphate proteoglycan biosynthesis, polysaccharide chain biosynthetic process|chondroitin sulfate B proteoglycan chain elongation|chondroitin sulfate B proteoglycan biosynthesis, polysaccharide chain biosynthetic process													biological_process											owl:Class	
GO:0060546	biolink:NamedThing	negative regulation of necroptotic process	Any process that decreases the rate, frequency or extent of a necroptotic process, a necrotic cell death process that results from the activation of endogenous cellular processes, such as signaling involving death domain receptors or Toll-like receptors.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of necroptosis							dph	2009-04-13T01:49:36Z					biological_process											owl:Class	
GO:0060128	biolink:NamedThing	corticotropin hormone secreting cell differentiation	The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a corticotropic hormone secreting cell. An corticotropic hormone secreting cell is a basophil cell of the anterior pituitary that produces corticotropin.	tmpzr1t_l9r_go_relaxed.owl	corticotrophin hormone secreting cell differentiation|adrenocorticotropic hormone secreting cell differentiation|corticotrope differentiation|adrenocorticotrophic hormone secreting cell differentiation|corticotroph differentiation													biological_process											owl:Class	
GO:0034240	biolink:NamedThing	negative regulation of macrophage fusion	Any process that stops, prevents, or decreases the frequency, rate or extent of macrophage fusion.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0034238	biolink:NamedThing	macrophage fusion	The binding and fusion of a macrophage to one or more other cells to form a multinucleated cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0000817	biolink:NamedThing	COMA complex	A kinetochore multiprotein complex that bridges the subunits that are in contact with centromeric DNA and the subunits bound to microtubules during kinetochore assembly. In yeast, consists of Ctf19p, Okp1p, Mcm21p, and Ame1p.	tmpzr1t_l9r_go_relaxed.owl	Ctf19p-Okp1p-Mcm1p-Ame1p complex	https://github.com/geneontology/go-ontology/issues/21126												cellular_component											owl:Class	
GO:0043324	biolink:NamedThing	pigment metabolic process involved in developmental pigmentation	The chemical reactions and pathways involving biological pigments e.g. melanin, occurring as part of the development of an organ or organism.	tmpzr1t_l9r_go_relaxed.owl	pigment metabolic process during developmental pigmentation|pigment metabolism during developmental pigmentation													biological_process											owl:Class	
GO:0035329	biolink:NamedThing	hippo signaling	The series of molecular signals mediated by the serine/threonine kinase Hippo or one of its orthologs. In Drosophila, Hippo in complex with the scaffold protein Salvador (Sav), phosphorylates and activates Warts (Wts), which in turn phosphorylates and inactivates the Yorkie (Yki) transcriptional activator. The core fly components hippo, sav, wts and mats are conserved in mammals as STK4/3 (MST1/2), SAV1/WW45, LATS1/2 and MOB1.	tmpzr1t_l9r_go_relaxed.owl	hippo signaling cascade|hippo signaling pathway|Salvador-Warts-Hippo signaling pathway|hippo signalling cascade|SWH pathway|hippo signal transduction							bf	2010-02-26T10:43:33Z					biological_process											owl:Class	
GO:0010248	biolink:NamedThing	establishment or maintenance of transmembrane electrochemical gradient	The directed movement of ions to establish or maintain an electrochemical gradient across a membrane by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0006099	biolink:NamedThing	tricarboxylic acid cycle	A nearly universal metabolic pathway in which the acetyl group of acetyl coenzyme A is effectively oxidized to two CO2 and four pairs of electrons are transferred to coenzymes. The acetyl group combines with oxaloacetate to form citrate, which undergoes successive transformations to isocitrate, 2-oxoglutarate, succinyl-CoA, succinate, fumarate, malate, and oxaloacetate again, thus completing the cycle. In eukaryotes the tricarboxylic acid is confined to the mitochondria. See also glyoxylate cycle.	tmpzr1t_l9r_go_relaxed.owl	TCA cycle|Krebs cycle|citric acid cycle				MetaCyc:P105-PWY|MetaCyc:P42-PWY|MetaCyc:TCA|Wikipedia:Tricarboxylic_acid_cycle									biological_process											owl:Class	
GO:0072221	biolink:NamedThing	metanephric distal convoluted tubule development	The process whose specific outcome is the progression of the metanephric distal convoluted tubule over time, from its formation to the mature structure. The metanephric distal convoluted tubule is the first segment of the metanephric nephron lying just downstream from the loop of Henle, immediately after the macula densa. Among other functions, in humans it is responsible for the reabsorption of about 5% of filtered sodium via the thiazide-sensitive Na-Cl symporter.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-03-18T03:35:27Z					biological_process											owl:Class	
GO:0019226	biolink:NamedThing	transmission of nerve impulse	The neurological system process in which a signal is transmitted through the nervous system by a combination of action potential propagation and synaptic transmission.	tmpzr1t_l9r_go_relaxed.owl	conduction of nerve impulse|signal transmission along a neuron													biological_process											owl:Class	
GO:0010152	biolink:NamedThing	pollen maturation	The final stages of microgametogenesis after the trinucleate stage has been reached resulting in viable pollen grains.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0034503	biolink:NamedThing	protein localization to nucleolar rDNA repeats	Any process in which a protein is transported to, or maintained at, the rDNA repeats on a chromosome in the nucleolus.	tmpzr1t_l9r_go_relaxed.owl	protein localisation to nucleolar rDNA repeats|condensin localization to nucleolar rDNA repeats													biological_process											owl:Class	
GO:0051355	biolink:NamedThing	proprioception involved in equilibrioception	The series of events contributing to equilibrioception by which an organism senses the position, location, orientation, and movement of the body and its parts. Proprioception plays an important role in the ability of an organism to perceive its orientation with respect to gravity.	tmpzr1t_l9r_go_relaxed.owl	perception of orientation with respect to gravity by proprioception|equilibrioception by proprioception|proprioception during equilibrioception													biological_process											owl:Class	
GO:0015567	biolink:NamedThing	alkane transmembrane transporter activity	Enables the transfer of alkanes from one side of a membrane to the other. Alkanes are saturated aliphatic hydrocarbon compounds.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0015895	biolink:NamedThing	alkane transport	The directed movement of alkanes into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Alkanes are saturated aliphatic hydrocarbon compounds.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0048850	biolink:NamedThing	hypophysis morphogenesis	The process in which the anatomical structures of the hypophysis are generated and organized. The pituitary gland is an endocrine gland that secretes hormones that regulate many other glands.	tmpzr1t_l9r_go_relaxed.owl	pituitary gland morphogenesis													biological_process											owl:Class	
GO:1900160	biolink:NamedThing	plastid DNA packaging	Any process in which plastidial DNA and associated proteins are formed into a compact, orderly structure.	tmpzr1t_l9r_go_relaxed.owl	DNA organization in plastid|DNA organisation in plastid|plastidial DNA packaging							bf	2012-03-08T10:51:50Z					biological_process											owl:Class	
GO:1903475	biolink:NamedThing	mitotic actomyosin contractile ring assembly	Any actomyosin contractile ring assembly that is involved in mitotic cytokinesis.	tmpzr1t_l9r_go_relaxed.owl	actomyosin contractile ring assembly involved in cytokinesis after mitosis|contractile ring assembly involved in mitotic cytokinesis|cytokinesis, actomyosin contractile ring assembly involved in mitotic cytokinesis							vw	2014-09-23T14:42:12Z					biological_process											owl:Class	
GO:0061423	biolink:NamedThing	positive regulation of sodium ion transport by positive regulation of transcription from RNA polymerase II promoter	Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter resulting in the increased frequency, rate or extent of the directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl								dph	2012-01-26T12:52:05Z					biological_process											owl:Class	
GO:0006814	biolink:NamedThing	sodium ion transport	The directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	sodium channel auxiliary protein activity|mitochondrial sodium/calcium ion exchange|sodium/potassium transport|sodium transport|sodium:calcium exchange|sodium:solute transport											GO:0006834|GO:0016974		biological_process											owl:Class	
GO:0140528	biolink:NamedThing	bilobe structure assembly	The assembly and organization of a bilobe structure, a cytoskeletal structure in some kinetoplastid species linking the structures of the ciliary pocket collar and the flagellum attachment zone (aka cilium attachment zone).	tmpzr1t_l9r_go_relaxed.owl	kinetoplastid flagellar hook complex assembly|bilobe structure formation|bilobe structure biogenesis	https://github.com/geneontology/go-ontology/issues/20057						pg	2020-09-30T08:47:39Z					biological_process											owl:Class	
GO:0042308	biolink:NamedThing	negative regulation of protein import into nucleus	Any process that stops, prevents, or reduces the frequency, rate or extent of the movement of proteins from the cytoplasm into the nucleus.	tmpzr1t_l9r_go_relaxed.owl	down regulation of protein import into nucleus|negative regulation of protein import into cell nucleus|down-regulation of protein import into nucleus|downregulation of protein import into nucleus|negative regulation of protein transport from cytoplasm to nucleus|negative regulation of protein-nucleus import|inhibition of protein import into nucleus													biological_process											owl:Class	
GO:1901197	biolink:NamedThing	positive regulation of calcium-mediated signaling involved in cellular response to calcium ion	Any positive regulation of calcium-mediated signaling that is involved in cellular response to calcium ion.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of calcium-mediated signaling involved in response to calcium ion|up regulation of calcium-mediated signaling involved in cellular response to Ca2+ ion|activation of calcium-mediated signaling involved in cellular response to Ca2+ ion|positive regulation of calcium-mediated signalling involved in cellular response to calcium ion|upregulation of calcium-mediated signaling involved in cellular response to Ca2+ ion|positive regulation of calcium-mediated signaling involved in cellular response to Ca2+ ion|activation of calcium-mediated signaling involved in cellular response to calcium ion|stimulation of calcium-mediated signaling involved in cellular response to Ca2+ ion|upregulation of calcium-mediated signaling involved in cellular response to calcium ion|stimulation of calcium-mediated signaling involved in cellular response to calcium ion|positive regulation of calcium-mediated signalling involved in cellular response to Ca2+ ion|up regulation of calcium-mediated signaling involved in cellular response to calcium ion|up-regulation of calcium-mediated signaling involved in cellular response to Ca2+ ion							al	2012-07-27T10:57:56Z					biological_process											owl:Class	
GO:0051610	biolink:NamedThing	serotonin uptake	The directed movement of serotonin into a cell, typically presynaptic neurons or glial cells. Serotonin (5-hydroxytryptamine) is a monoamine neurotransmitter occurring in the peripheral and central nervous systems.	tmpzr1t_l9r_go_relaxed.owl	5HT uptake|5-hydroxytryptamine uptake|serotonin import|5-HT uptake													biological_process											owl:Class	
GO:1905677	biolink:NamedThing	regulation of adaptive immune effector response	Any process that modulates the frequency, rate or extent of adaptive immune effector response.	tmpzr1t_l9r_go_relaxed.owl								tb	2016-11-11T22:24:57Z					biological_process											owl:Class	
GO:0010607	biolink:NamedThing	negative regulation of cytoplasmic mRNA processing body assembly	Any process that decreases the rate, frequency, or extent of the aggregation, arrangement and bonding together of proteins and RNA molecules to form a cytoplasmic mRNA processing body.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1990764	biolink:NamedThing	myofibroblast contraction	The actin filament-based process in which cytoplasmic actin filaments slide past one another resulting in contraction of a myofibroblast.	tmpzr1t_l9r_go_relaxed.owl	MFB contraction|MF contraction							sl	2015-06-09T23:43:09Z					biological_process											owl:Class	
GO:0032889	biolink:NamedThing	regulation of vacuole fusion, non-autophagic	Any process that modulates the frequency, rate or extent of the fusion of two vacuole membranes to form a single vacuole.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0071773	biolink:NamedThing	cellular response to BMP stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bone morphogenetic protein (BMP) stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to bone morphogenetic protein stimulus							mah	2010-08-31T11:04:45Z					biological_process											owl:Class	
GO:0002349	biolink:NamedThing	histamine production involved in inflammatory response	The synthesis or release of histamine following a stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels.	tmpzr1t_l9r_go_relaxed.owl	histamine production involved in acute inflammatory response													biological_process											owl:Class	
GO:0007129	biolink:NamedThing	homologous chromosome pairing at meiosis	The meiotic cell cycle process where side by side pairing and physical juxtaposition of homologous chromosomes is created during meiotic prophase. Homologous chromosome pairing begins when the chromosome arms begin to pair from the clustered telomeres and ends when synaptonemal complex or linear element assembly is complete.	tmpzr1t_l9r_go_relaxed.owl	chromosomal synapsis|synapsis|chromosomal pairing				Wikipedia:Synapsis									biological_process											owl:Class	
GO:0035550	biolink:NamedThing	urease complex	A multiprotein nickel-containing complex that possesses urease activity (catalysis of the hydrolysis of urea to ammonia and carbon dioxide).	tmpzr1t_l9r_go_relaxed.owl						Eukaryotic microorganisms, plants, and probably Gram-positive bacteria, possess a homopolymeric urease. In contrast, urease complexes from gram-negative bacteria studied thus far clearly possess three distinct subunits (alpha, beta and gamma). Tightly bound nickel is present in all urease complexes.		bf	2010-05-12T01:00:27Z					cellular_component											owl:Class	
GO:0071769	biolink:NamedThing	mycolate cell wall layer assembly	The aggregation, arrangement and bonding together of a set of components, including arabinogalactan mycolate and trehalose dimycolate, to form the mycolate layer of the Actinobacterium-type cell wall. The mycolate layer is physically attached to the peptidoglycan layer.	tmpzr1t_l9r_go_relaxed.owl	mycolate cell wall layer biogenesis				MetaCyc:PWY-6397			mah	2010-03-29T04:40:45Z					biological_process											owl:Class	
GO:0032178	biolink:NamedThing	medial membrane band	A sterol-rich region of the plasma membrane which forms at the cell surface overlying the contractile ring and spreads into the invaginating plasma membrane surrounding the septum.	tmpzr1t_l9r_go_relaxed.owl	sterol-rich membrane band													cellular_component											owl:Class	
GO:0032153	biolink:NamedThing	cell division site	The eventual plane of cell division (also known as cell cleavage or cytokinesis) in a dividing cell. In Eukaryotes, the cleavage apparatus, composed of septin structures and the actomyosin contractile ring, forms along this plane, and the mitotic, or meiotic, spindle is aligned perpendicular to the division plane. In bacteria, the cell division site is generally located at mid-cell and is the site at which the cytoskeletal structure, the Z-ring, assembles.	tmpzr1t_l9r_go_relaxed.owl	cell division plane					Note that this term refers to the future site of division in a cell that has not yet divided.								cellular_component											owl:Class	
GO:0039536	biolink:NamedThing	negative regulation of RIG-I signaling pathway	Any process that stops, prevents, or reduces the frequency, rate or extent of the series of molecular signals generated as a consequence of the cytoplasmic pattern recognition receptor (PRR) RIG-1 (also known as DDX58) binding to viral RNA.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of retinoic acid inducible gene I signaling pathway|negative regulation of RIG-I signalling pathway|negative regulation of DDX58 signaling pathway							bf	2012-01-03T11:27:51Z					biological_process											owl:Class	
GO:0035494	biolink:NamedThing	SNARE complex disassembly	The disaggregation of the SNARE protein complex into its constituent components. The SNARE complex is a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers.	tmpzr1t_l9r_go_relaxed.owl								bf	2010-04-26T02:54:17Z					biological_process											owl:Class	
GO:0001992	biolink:NamedThing	regulation of systemic arterial blood pressure by vasopressin	The regulation of blood pressure mediated by the signaling molecule vasopressin. Vasopressin is produced in the hypothalamus, and affects vasoconstriction, and renal water transport.	tmpzr1t_l9r_go_relaxed.owl	blood pressure regulation by vasopressin|vasopressin control of blood pressure													biological_process											owl:Class	
GO:0014032	biolink:NamedThing	neural crest cell development	The process aimed at the progression of a neural crest cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0070124	biolink:NamedThing	mitochondrial translational initiation	The process preceding formation of the peptide bond between the first two amino acids of a protein in a mitochondrion. This includes the formation of a complex of the ribosome, mRNA, and an initiation complex that contains the first aminoacyl-tRNA.	tmpzr1t_l9r_go_relaxed.owl	mitochondrial translation initiation													biological_process											owl:Class	
GO:0030325	biolink:NamedThing	adrenal gland development	The process whose specific outcome is the progression of the adrenal gland over time, from its formation to the mature structure. This gland can either be a discrete structure located bilaterally above each kidney, or a cluster of cells in the head kidney that perform the functions of the adrenal gland. In either case, this organ consists of two cells types, aminergic chromaffin cells and steroidogenic cortical cells.	tmpzr1t_l9r_go_relaxed.owl	interrenal gland													biological_process											owl:Class	
GO:0038112	biolink:NamedThing	interleukin-8-mediated signaling pathway	A series of molecular signals initiated by the binding of interleukin-8 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.	tmpzr1t_l9r_go_relaxed.owl	IL-8-mediated signaling pathway|interleukin-8-mediated signalling pathway							bf	2012-03-22T10:19:59Z					biological_process											owl:Class	
GO:0021647	biolink:NamedThing	vestibulocochlear nerve maturation	A developmental process, independent of morphogenetic (shape) change, that is required for the vestibulocochlear nerve to attain its fully functional state. This sensory nerve innervates the membranous labyrinth of the inner ear. The vestibular branch innervates the vestibular apparatus that senses head position changes relative to gravity. The auditory branch innervates the cochlear duct, which is connected to the three bony ossicles which transduce sound waves into fluid movement in the cochlea.	tmpzr1t_l9r_go_relaxed.owl	CN VIII maturation|auditory nerve maturation													biological_process											owl:Class	
GO:0021562	biolink:NamedThing	vestibulocochlear nerve development	The process whose specific outcome is the progression of the vestibulocochlear nerve over time, from its formation to the mature structure. This sensory nerve innervates the membranous labyrinth of the inner ear. The vestibular branch innervates the vestibular apparatus that senses head position changes relative to gravity. The auditory branch innervates the cochlear duct, which is connected to the three bony ossicles which transduce sound waves into fluid movement in the cochlea.	tmpzr1t_l9r_go_relaxed.owl	cranial nerve 8 development|cranial nerve VIII development|CN VIII development|acoustic nerve development													biological_process											owl:Class	
GO:0002611	biolink:NamedThing	negative regulation of plasmacytoid dendritic cell antigen processing and presentation	Any process that stops, prevents, or reduces the frequency, rate, or extent of plasmacytoid dendritic cell antigen processing and presentation.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of plasmacytoid dendritic cell antigen processing and presentation|down regulation of plasmacytoid dendritic cell antigen processing and presentation|downregulation of plasmacytoid dendritic cell antigen processing and presentation|inhibition of plasmacytoid dendritic cell antigen processing and presentation													biological_process											owl:Class	
GO:0048914	biolink:NamedThing	myelination of anterior lateral line nerve axons	The formation of compact myelin sheaths around the axons of the anterior lateral line nerve.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0048940	biolink:NamedThing	anterior lateral line nerve glial cell morphogenesis involved in differentiation	The process in which the structures of a glial cell in the anterior lateral line nerve are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a glial cell in the anterior lateral line nerve.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1900164	biolink:NamedThing	nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry	A series of molecular signals initiated by the binding of a nodal protein to an activin receptor on the surface of a target cell, which contributes to the establishment of lateral mesoderm with respect to the left and right halves.	tmpzr1t_l9r_go_relaxed.owl	nodal signalling pathway involved in determination of lateral mesoderm left/right asymmetry|nodal signaling pathway of determination of left/right asymmetry in lateral mesoderm|nodal signaling of determination of left/right asymmetry in lateral mesoderm							bf	2012-03-08T02:58:39Z					biological_process											owl:Class	
GO:1904819	biolink:NamedThing	parietal peritoneum development	The process whose specific outcome is the progression of a parietal peritoneum over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl	peritoneal cavity lining development							dph	2015-11-17T19:00:24Z					biological_process											owl:Class	
GO:1904820	biolink:NamedThing	peritoneum development	The process whose specific outcome is the progression of a peritoneum over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl	peritonaeum development							dph	2015-11-18T17:23:51Z					biological_process											owl:Class	
GO:0035516	biolink:NamedThing	oxidative DNA demethylase activity	Catalysis of the reaction: a methylated nucleobase within DNA + 2-oxoglutarate + O(2) =  a nucleobase within DNA + formaldehyde + succinate + CO(2).	tmpzr1t_l9r_go_relaxed.owl	2-oxoglutarate-dependent DNA demethylase|N1-methyladenine demethylase activity|1-ethyladenine demethylase activity|N3-methylcytosine demethylase activity	https://github.com/geneontology/go-ontology/issues/21159			RHEA:30299|MetaCyc:RXN0-985|MetaCyc:RXN0-986|MetaCyc:RXN0-984|EC:1.14.11.33			bf	2010-04-30T02:38:16Z			GO:0103051|GO:0103052|GO:0103053		molecular_function											owl:Class	
GO:0035511	biolink:NamedThing	oxidative DNA demethylation	Removal of the methyl group from one or more nucleotides within a DNA molecule involving the oxidation (i.e. electron loss) of one or more atoms.	tmpzr1t_l9r_go_relaxed.owl								bf	2010-04-30T02:22:44Z					biological_process											owl:Class	
GO:0090232	biolink:NamedThing	positive regulation of spindle checkpoint	Any process that increases the rate, frequency, or extent of the spindle checkpoint, a cell cycle checkpoint that delays the metaphase/anaphase transition until the spindle is correctly assembled and oriented, and chromosomes are attached to the spindle.	tmpzr1t_l9r_go_relaxed.owl	spindle checkpoint activation							tb	2010-01-20T10:29:43Z					biological_process											owl:Class	
GO:0031577	biolink:NamedThing	spindle checkpoint signaling	A signaling process that that controls a cell cycle checkpoint that originates from the mitotic or meiotic spindle.	tmpzr1t_l9r_go_relaxed.owl	spindle checkpoint|signal transduction involved in spindle checkpoint	https://github.com/geneontology/go-ontology/issues/20935			Wikipedia:Spindle_checkpoint	Note that this term should not be used for direct manual annotation as it should always be possible to choose either a mitotic or meiotic child term.						GO:0072416		biological_process											owl:Class	
GO:0032623	biolink:NamedThing	interleukin-2 production	The appearance of interleukin-2 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	tmpzr1t_l9r_go_relaxed.owl	IL-2 production|interleukin-2 secretion|interleukin-2 biosynthetic process											GO:0042094|GO:0070970		biological_process											owl:Class	
GO:0071714	biolink:NamedThing	icosanoid transmembrane transporter activity	Enables the transfer of icosanoids from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	eicosanoid transmembrane transporter activity							mah	2010-03-10T01:50:08Z					molecular_function											owl:Class	
GO:0035263	biolink:NamedThing	genital disc sexually dimorphic development	The sex-specific patterns of primoridia growth and differentiation in the genital imaginal disc. The anal primordium of the genital disc develops in both sexes, but depending on the genetic sex gives rise to either male or female analia. Depending on the genetic sex, only one of the two genital primordia develop. In females the female genital primordium develops and gives rise to the female genitalia whereas the male primordium is repressed. Conversely, in males the male genital primordium develops and gives rise to the male genitalia whereas the female genital primordium is repressed.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0035215	biolink:NamedThing	genital disc development	Progression of the genital imaginal disc over time, from its initial formation through to its metamorphosis to form the adult terminalia, comprising the entire set of internal and external genitalia and analia. Both sexes of Drosophila have a single genital disc formed from the female and male genital primordia, and the anal primordium. The anal primordium develops in both sexes, forming either male or female analia. However, only one of the genital primordia develops in each sex, forming either the male or the female genitalia.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0034179	biolink:NamedThing	regulation of toll-like receptor 13 signaling pathway	Any process that modulates the frequency, rate, or extent of toll-like receptor 13 signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	regulation of toll-like receptor 13 signalling pathway|regulation of TLR13 signaling pathway													biological_process											owl:Class	
GO:0001713	biolink:NamedThing	ectodermal cell fate determination	The cell fate determination process that results in a cell becoming capable of differentiating autonomously into an ectoderm cell regardless of its environment; upon determination, the cell fate cannot be reversed.	tmpzr1t_l9r_go_relaxed.owl	ectoderm cell fate determination													biological_process											owl:Class	
GO:0001712	biolink:NamedThing	ectodermal cell fate commitment	The cell differentiation process that results in commitment of a cell to become part of the ectoderm.	tmpzr1t_l9r_go_relaxed.owl	ectoderm cell fate commitment													biological_process											owl:Class	
GO:0045053	biolink:NamedThing	protein retention in Golgi apparatus	The retention of proteins within the Golgi apparatus. Golgi-localized carbohydrate-modifying enzymes have a short N-terminal domain that faces the cytosol, a single transmembrane alpha helix, and a large C-terminal domain that faces the Golgi lumen and that contains the catalytic site. How the membrane-spanning alpha helix in a Golgi enzyme causes its localization and prevents its movement to the plasma membrane is not known.	tmpzr1t_l9r_go_relaxed.owl	maintenance of protein location in Golgi apparatus|protein-Golgi retention|retention of protein in Golgi													biological_process											owl:Class	
GO:0034067	biolink:NamedThing	protein localization to Golgi apparatus	A process in which a protein is transported to, or maintained in, a location within the Golgi apparatus.	tmpzr1t_l9r_go_relaxed.owl	establishment of protein localization to Golgi|establishment of protein localization in Golgi|establishment of protein localisation to Golgi|establishment of protein localization to Golgi apparatus|protein localisation in Golgi apparatus|protein-Golgi targeting|protein localization in Golgi apparatus|protein targeting to Golgi							mah	2011-02-14T02:26:36Z			GO:0072600|GO:0000042		biological_process											owl:Class	
GO:1902988	biolink:NamedThing	neurofibrillary tangle assembly	The aggregation, arrangement and bonding together of a set of components to form a neurofibrillary tangle.	tmpzr1t_l9r_go_relaxed.owl	neurofibrillary tangle formation|flame-shaped neurofibrillary tangle assembly|star-shaped neurofibrillary tangle assembly|star-shaped neurofibrillary tangle formation|flame-shaped neurofibrillary tangle formation					Neurofibrillary tangles have been found in aging population; their formation is increased in Alzheimer's disease patients (and in other neurological diseases) compared to normal controls (see PMID:848276 and PMID:8584267).		sjp	2014-05-08T09:19:51Z					biological_process											owl:Class	
GO:0140659	biolink:NamedThing	cytoskeletal motor regulator activity	Binds to and modulates the activity of a motor protein.	tmpzr1t_l9r_go_relaxed.owl	motor activity regulator activity	https://github.com/geneontology/go-ontology/issues/21627|https://github.com/geneontology/go-ontology/issues/21756						pg	2021-06-16T11:16:00Z					molecular_function											owl:Class	
GO:1905561	biolink:NamedThing	positive regulation of kinetochore assembly	Any process that activates or increases the frequency, rate or extent of kinetochore assembly.	tmpzr1t_l9r_go_relaxed.owl	up regulation of centromere/kinetochore complex maturation|upregulation of kinetochore assembly|positive regulation of chromosome-kinetochore attachment|up regulation of centromere and kinetochore complex maturation|up-regulation of centromere/kinetochore complex maturation|upregulation of kinetochore formation|up-regulation of chromosome-kinetochore attachment|activation of centromere and kinetochore complex maturation|up regulation of kinetochore assembly|activation of chromosome-kinetochore attachment|positive regulation of kinetochore formation|up regulation of kinetochore formation|upregulation of chromosome-kinetochore attachment|up-regulation of centromere and kinetochore complex maturation|activation of kinetochore formation|activation of centromere/kinetochore complex maturation|positive regulation of centromere/kinetochore complex maturation|positive regulation of centromere and kinetochore complex maturation|up-regulation of kinetochore formation|upregulation of centromere and kinetochore complex maturation|up regulation of chromosome-kinetochore attachment|activation of kinetochore assembly|up-regulation of kinetochore assembly|upregulation of centromere/kinetochore complex maturation							hbye	2016-10-14T13:47:45Z					biological_process											owl:Class	
GO:0097083	biolink:NamedThing	vascular associated smooth muscle cell fate determination	The process in which a cell becomes capable of differentiating autonomously into a vascular smooth muscle cell regardless of its environment; upon determination, the cell fate cannot be reversed. A vascular smooth muscle cell is a non-striated, elongated, spindle-shaped cell found lining the blood vessels.	tmpzr1t_l9r_go_relaxed.owl	vascular smooth muscle cell fate determination							pr	2011-06-20T04:00:28Z					biological_process											owl:Class	
GO:0061276	biolink:NamedThing	mesonephric proximal tubule morphogenesis	The process in which the anatomical structures of a mesonephric proximal tubule are generated and organized. The mesonephric proximal tubule extends from the capsule to the distal tubule.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-09-02T01:11:02Z					biological_process											owl:Class	
GO:0097484	biolink:NamedThing	dendrite extension	Long distance growth of a single dendrite involved in cellular development.	tmpzr1t_l9r_go_relaxed.owl								pr	2013-07-08T09:52:31Z					biological_process											owl:Class	
GO:0023019	biolink:NamedThing	signal transduction involved in regulation of gene expression	Any process that modulates the frequency, rate or extent of gene expression as a consequence of a process in which a signal is released and/or conveyed from one location to another.	tmpzr1t_l9r_go_relaxed.owl	regulation of gene expression as a consequence of signal transmission								2010-02-16T09:30:50Z					biological_process											owl:Class	
GO:0034457	biolink:NamedThing	Mpp10 complex	A protein complex that forms a subcomplex of the 90S preribosome. In S. cerevisiae, it is composed of Mpp10p, Imp3p and Imp4p.	tmpzr1t_l9r_go_relaxed.owl						Note that the term name uses Saccharomyces gene product names because no other names have yet arisen for this complex; the term nevertheless can be used for analogous complexes in other eukaryotes, and the name can be changed if better wording is found.								cellular_component											owl:Class	
GO:2000820	biolink:NamedThing	negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation	Any negative regulation of transcription from RNA polymerase II promoter that is involved in smooth muscle cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of global transcription from RNA polymerase II promoter involved in nonstriated muscle cell differentiation|negative regulation of transcription from RNA polymerase II promoter involved in nonstriated muscle cell differentiation|negative regulation of transcription from Pol II promoter involved in smooth muscle cell differentiation|negative regulation of gene-specific transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation|down regulation of transcription from RNA polymerase II promoter involved in nonstriated muscle cell differentiation|negative regulation of transcription from RNA polymerase II promoter, global involved in nonstriated muscle cell differentiation|down regulation of global transcription from RNA polymerase II promoter involved in nonstriated muscle cell differentiation|inhibition of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation|downregulation of transcription from RNA polymerase II promoter involved in nonstriated muscle cell differentiation|downregulation of global transcription from RNA polymerase II promoter involved in nonstriated muscle cell differentiation|inhibition of global transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation|down-regulation of global transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation|downregulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation|down regulation of global transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation|down-regulation of transcription from RNA polymerase II promoter involved in nonstriated muscle cell differentiation|inhibition of transcription from RNA polymerase II promoter involved in nonstriated muscle cell differentiation|negative regulation of gene-specific transcription from RNA polymerase II promoter involved in nonstriated muscle cell differentiation|negative regulation of global transcription from Pol II promoter involved in nonstriated muscle cell differentiation|negative regulation of transcription from Pol II promoter involved in nonstriated muscle cell differentiation|downregulation of global transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation|negative regulation of global transcription from Pol II promoter involved in smooth muscle cell differentiation|down-regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation|inhibition of global transcription from RNA polymerase II promoter involved in nonstriated muscle cell differentiation|down regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation|negative regulation of transcription from RNA polymerase II promoter, global involved in smooth muscle cell differentiation							bf	2011-07-14T08:25:05Z					biological_process											owl:Class	
GO:0070262	biolink:NamedThing	peptidyl-serine dephosphorylation	The removal of phosphoric residues from peptidyl-O-phospho-L-serine to form peptidyl-serine.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1903590	biolink:NamedThing	regulation of lysozyme activity	Any process that modulates the frequency, rate or extent of lysozyme activity.	tmpzr1t_l9r_go_relaxed.owl	regulation of PR1-lysozyme|regulation of lysozyme g|regulation of N,O-diacetylmuramidase activity|regulation of globulin G|regulation of L-7001|regulation of peptidoglycan N-acetylmuramoylhydrolase activity|regulation of mucopeptide N-acetylmuramoylhydrolase activity|regulation of mucopeptide glucohydrolase activity|regulation of globulin G1|regulation of 1,4-N-acetylmuramidase activity|regulation of muramidase activity							mr	2014-11-05T21:41:22Z					biological_process											owl:Class	
GO:0097422	biolink:NamedThing	tubular endosome	A network of fine tubules in the vicinity of the Golgi complex and around the centriole.	tmpzr1t_l9r_go_relaxed.owl	coated tip				NIF_Subcellular:sao694815499|NIF_Subcellular:sao1570660411			pr	2012-11-07T13:36:26Z					cellular_component											owl:Class	
GO:0034493	biolink:NamedThing	melanosome lumen	The volume enclosed by the melanosome membrane.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0042470	biolink:NamedThing	melanosome	A tissue-specific, membrane-bounded cytoplasmic organelle within which melanin pigments are synthesized and stored. Melanosomes are synthesized in melanocyte cells.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Melanosome									cellular_component											owl:Class	
GO:0033687	biolink:NamedThing	osteoblast proliferation	The multiplication or reproduction of osteoblasts, resulting in the expansion of an osteoblast cell population. An osteoblast is a bone-forming cell which secretes an extracellular matrix. Hydroxyapatite crystals are then deposited into the matrix to form bone.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0021728	biolink:NamedThing	inferior reticular formation development	The process whose specific outcome is the progression of the inferior reticular formation over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0060402	biolink:NamedThing	calcium ion transport into cytosol	The directed movement of calcium ions (Ca2+) into the cytosol.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0001985	biolink:NamedThing	negative regulation of heart rate involved in baroreceptor response to increased systemic arterial blood pressure	Any process that stops, prevents, or reduces the frequency, rate or extent of heart contraction as a result of the baroreceptor response to increased blood pressure.	tmpzr1t_l9r_go_relaxed.owl	downregulation of heart contraction rate in baroreceptor response to increased blood pressure|down-regulation of heart contraction rate in baroreceptor response to increased blood pressure|down regulation of heart contraction rate in baroreceptor response to increased blood pressure|negative regulation of heart contraction rate in baroreceptor response to increased blood pressure|negative regulation of cardiac contraction rate in baroreceptor response to increased blood pressure|inhibition of heart contraction rate in baroreceptor response to increased blood pressure|negative control of heart contraction rate in baroreceptor response to increased blood pressure													biological_process											owl:Class	
GO:0042412	biolink:NamedThing	taurine biosynthetic process	The chemical reactions and pathways resulting in the formation of taurine (2-aminoethanesulfonic acid), a sulphur-containing amino acid derivative important in the metabolism of fats.	tmpzr1t_l9r_go_relaxed.owl	taurine synthesis|taurine anabolism|taurine biosynthesis|taurine formation													biological_process											owl:Class	
GO:0072539	biolink:NamedThing	T-helper 17 cell differentiation	The process in which a relatively unspecialized T cell acquires the specialized features of a T-helper 17 (Th17) cell. A Th17 cell is a CD4-positive, alpha-beta T cell with the phenotype RORgamma-t-positive that produces IL-17.	tmpzr1t_l9r_go_relaxed.owl	T-helper 17 cell development					Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.		mah	2011-01-17T11:18:47Z					biological_process											owl:Class	
GO:0061227	biolink:NamedThing	pattern specification involved in mesonephros development	Any developmental process that results in the creation of defined areas or spaces within the mesonephros to which cells respond and eventually are instructed to differentiate.	tmpzr1t_l9r_go_relaxed.owl	mesonephros pattern specification|mesonephros pattern formation							dph	2010-08-19T02:22:22Z					biological_process											owl:Class	
GO:0097653	biolink:NamedThing	unencapsulated part of cell	The part of a cell encompassing the intracellular environment and the plasma membrane; it excludes any external encapsulating structures.	tmpzr1t_l9r_go_relaxed.owl	non-encapsulated part of cell							pr	2014-09-23T12:57:14Z					cellular_component											owl:Class	
GO:0060435	biolink:NamedThing	bronchiole development	The biological process whose specific outcome is the progression of a bronchiole from an initial condition to its mature state. This process begins with the formation of the bronchiole and ends with the mature structure. A bronchiole is the first airway branch that no longer contains cartilage; it is a branch of the bronchi.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1903198	biolink:NamedThing	regulation of L-dopa decarboxylase activity	Any process that modulates the frequency, rate or extent of L-dopa decarboxylase activity.	tmpzr1t_l9r_go_relaxed.owl	regulation of DDC activity|regulation of 4-dihydroxyl-L-phenylalanine decarboxylase activity|regulation of DOPA decarboxylase activity							bf	2014-07-21T09:32:31Z					biological_process											owl:Class	
GO:0031209	biolink:NamedThing	SCAR complex	A pentameric complex that includes orthologues of human PIR121, Nap1, Abi, SCAR, and HSPC300 and regulates actin polymerization and/or depolymerization through small GTPase mediated signal transduction.	tmpzr1t_l9r_go_relaxed.owl	WAVE complex|WAVE regulatory complex|WRC													cellular_component											owl:Class	
GO:0033292	biolink:NamedThing	T-tubule organization	A process that is carried out at the cellular level that results in the assembly, arrangement of constituent parts, or disassembly of the T-tubule. A T-tubule is an invagination of the plasma membrane of a muscle cell that extends inward from the cell surface around each myofibril.	tmpzr1t_l9r_go_relaxed.owl	T-tubule organization and biogenesis|T-tubule organisation|transverse tubule organization													biological_process											owl:Class	
GO:0032797	biolink:NamedThing	SMN complex	A protein complex that contains the survival motor neuron (SMN) protein and at least eight additional integral components, including the Gemin2-8 and Unrip proteins; the complex is found in the cytoplasm and in nuclear Gems, and is involved in spliceosomal snRNP assembly in the cytoplasm and in pre-mRNA splicing in the nucleus.	tmpzr1t_l9r_go_relaxed.owl	survival motor neuron complex|SMN core complex					Note that a larger complex containing Sm proteins and other subunits is also sometimes referred to as the 'SMN complex'. The larger complex is represented by 'SMN-Sm protein complex ; GO:0034719'.								cellular_component											owl:Class	
GO:0075226	biolink:NamedThing	encysted zoospore germination	The physiological, developmental and morphological changes that occur in an encysted zoospore, that germinates by developing a germ tube that may penetrate the host directly or indirectly through an appressorium. An encysted zoospore is a zoospore which has shed its flagellum and whose membrane has fused to form a walled cyst. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	encysted zoospore germination on or near host					Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products from the symbiont involved in this process.								biological_process											owl:Class	
GO:0060308	biolink:NamedThing	GTP cyclohydrolase I regulator activity	Binds to and modulates the activity of GTP cyclohydrolase I. GTP cyclohydrolase I activity catalyzes the reaction: GTP + 2 H2O = formate + 2-amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl)-dihydropteridine triphosphate.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0044549	biolink:NamedThing	GTP cyclohydrolase binding	Binding to a GTP cyclohydrolase.	tmpzr1t_l9r_go_relaxed.owl	GTP cyclohydrolase I binding							jl	2012-03-22T04:38:14Z			GO:0043106		molecular_function											owl:Class	
GO:0071722	biolink:NamedThing	detoxification of arsenic-containing substance	Any process that reduces or removes the toxicity of compounds containing arsenic, including arsenates, arsenites, and arsenides. These include transport of such compounds away from sensitive areas and to compartments or complexes whose purpose is sequestration of arsenic or arsenic-containing compounds.	tmpzr1t_l9r_go_relaxed.owl	detoxification of arsenic							mah	2010-03-17T01:35:56Z					biological_process											owl:Class	
GO:0007300	biolink:NamedThing	ovarian nurse cell to oocyte transport	Transfer of constituents synthesized in the ovarian nurse cells to the oocyte, through the ring canals, as the egg chamber is growing. An example of this is found in Drosophila melanogaster.	tmpzr1t_l9r_go_relaxed.owl	nurse cell to oocyte transport													biological_process											owl:Class	
GO:0003342	biolink:NamedThing	proepicardium development	The progression of the proepicardium from its formation to the mature structure. The proepicardium is an outpouching of the septum transversum.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-12-01T10:30:17Z					biological_process											owl:Class	
GO:0036092	biolink:NamedThing	phosphatidylinositol-3-phosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of phosphatidylinositol-3-phosphate, a phosphatidylinositol monophosphate carrying the phosphate group at the 3-position.	tmpzr1t_l9r_go_relaxed.owl	PtdIns3P biosynthesis|phosphatidylinositol-3-phosphate formation|PI(3)P biosynthesis|phosphatidylinositol-3-phosphate synthesis|phosphatidylinositol-3-phosphate anabolism|phosphatidylinositol-3-phosphate biosynthesis							bf	2012-01-13T02:13:57Z					biological_process											owl:Class	
GO:0005275	biolink:NamedThing	amine transmembrane transporter activity	Enables the transfer of amines, including polyamines, from one side of a membrane to the other. Amines are organic compounds that are weakly basic in character and contain an amino (-NH2) or substituted amino group.	tmpzr1t_l9r_go_relaxed.owl	amine/polyamine transmembrane transporter activity|amino acid-polyamine transmembrane transporter activity|amine/amide/polyamine channel activity											GO:0005279		molecular_function											owl:Class	
GO:1904243	biolink:NamedThing	negative regulation of pancreatic trypsinogen secretion	Any process that stops, prevents or reduces the frequency, rate or extent of pancreatic trypsinogen secretion.	tmpzr1t_l9r_go_relaxed.owl	downregulation of pancreatic trypsinogen secretion|negative regulation of pancreatic trypsinogen release|inhibition of pancreatic trypsinogen secretion|down regulation of pancreatic trypsinogen release|inhibition of pancreatic trypsinogen release|down regulation of pancreatic trypsinogen secretion|downregulation of pancreatic trypsinogen release|down-regulation of pancreatic trypsinogen secretion|down-regulation of pancreatic trypsinogen release							sl	2015-05-18T19:49:27Z					biological_process											owl:Class	
GO:0002492	biolink:NamedThing	peptide antigen assembly with MHC class Ib protein complex	The binding of a peptide antigen to the antigen binding groove of an MHC class Ib protein complex. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E gene family.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0072233	biolink:NamedThing	metanephric thick ascending limb development	The process whose specific outcome is the progression of the metanephric thick ascending limb over time, from its formation to the mature structure. The metanephric thick ascending limb is the last part of the metanephric loop of Henle. Its thick, mitochondria-rich epithelium characterizes the outer medulla, and is responsible for very avid active salt transport. At the macula densa, the thick ascending limb connects to the distal convoluted tubule.	tmpzr1t_l9r_go_relaxed.owl	metanephric TAL development							mah	2010-03-18T03:39:36Z					biological_process											owl:Class	
GO:0098999	biolink:NamedThing	extrinsic component of postsynaptic endosome membrane	The component of the postsynaptic endosome membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0090057	biolink:NamedThing	root radial pattern formation	The radial pattern formation process that results in the formation of the different tissues of the root around its radial axis.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-08-11T02:58:06Z					biological_process											owl:Class	
GO:0098028	biolink:NamedThing	virus tail, shaft	The tube of the non-contractile tails of some viruses.	tmpzr1t_l9r_go_relaxed.owl	bacteriophage tail shaft					This term applies in particular to the Siphoviridae bacteriophages, where the shaft is the channel for DNA translocation into the host cytoplasm.		bm	2012-07-19T14:24:28Z					cellular_component											owl:Class	
GO:1990379	biolink:NamedThing	lipid transport across blood-brain barrier	The directed movement of lipid molecules passing through the blood-brain barrier.	tmpzr1t_l9r_go_relaxed.owl	lipid transport across blood brain barrier							sjp	2014-05-08T09:52:28Z					biological_process											owl:Class	
GO:0045733	biolink:NamedThing	acetate catabolic process	The chemical reactions and pathways resulting in the breakdown of acetate, the anion of acetic acid.	tmpzr1t_l9r_go_relaxed.owl	acetate catabolism|homoacetate catabolic process|acetate breakdown|acetate degradation											GO:0019663		biological_process											owl:Class	
GO:1900144	biolink:NamedThing	positive regulation of BMP secretion	Any process that activates or increases the frequency, rate or extent of BMP secretion.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of BMP secretion|up regulation of BMP protein secretion|up-regulation of bone morphogenetic protein secretion|positive regulation of bone morphogenetic protein secretion|upregulation of BMP secretion|upregulation of bone morphogenetic protein secretion|activation of bone morphogenetic protein secretion|positive regulation of BMP protein secretion|up-regulation of BMP protein secretion|upregulation of BMP protein secretion|activation of BMP secretion|up regulation of bone morphogenetic protein secretion|activation of BMP protein secretion|up regulation of BMP secretion							sart	2012-03-06T10:31:47Z					biological_process											owl:Class	
GO:0070963	biolink:NamedThing	positive regulation of neutrophil mediated killing of gram-negative bacterium	Any process that increases the frequency, rate or extent of the directed killing of a gram-negative bacterium by a neutrophil.	tmpzr1t_l9r_go_relaxed.owl	activation of neutrophil mediated killing of gram-negative bacterium|up regulation of neutrophil mediated killing of gram-negative bacterium|upregulation of neutrophil mediated killing of gram-negative bacterium|up-regulation of neutrophil mediated killing of gram-negative bacterium|stimulation of neutrophil mediated killing of gram-negative bacterium							mah	2009-10-01T02:28:49Z					biological_process											owl:Class	
GO:0010006	biolink:NamedThing	Toc complex	Protein translocon complex at the chloroplast outer membrane.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:1900322	biolink:NamedThing	negative regulation of maltotetraose transport	Any process that stops, prevents or reduces the frequency, rate or extent of maltotetraose transport.	tmpzr1t_l9r_go_relaxed.owl	down regulation of maltotetraose transport|downregulation of maltotetraose transport|down-regulation of maltotetraose transport|inhibition of maltotetraose transport							tt	2012-04-06T01:45:45Z					biological_process											owl:Class	
GO:2000251	biolink:NamedThing	positive regulation of actin cytoskeleton reorganization	Any process that activates or increases the frequency, rate or extent of actin cytoskeleton reorganization.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of actin cytoskeleton remodeling|positive regulation of actin cytoskeleton reorganisation							vk	2010-11-11T01:25:32Z					biological_process											owl:Class	
GO:0009531	biolink:NamedThing	secondary cell wall	A plant cell wall that is no longer able to expand and so does not permit growth. Secondary cell walls contain less pectin that primary cell walls. The secondary cell is mostly composed of cellulose and is strengthened with lignin.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Secondary_cell_wall									cellular_component											owl:Class	
GO:0000354	biolink:NamedThing	cis assembly of pre-catalytic spliceosome	Assembly of a spliceosomal complex containing the intact pre-mRNA and all of the spliceosomal snRNPs. This occurs when the tri-snRNP associates with the pre-mRNA and associated snRNPs in an ATP-dependent manner.	tmpzr1t_l9r_go_relaxed.owl	cis assembly of U12-type pre-catalytic spliceosome|spliceosomal B1 complex formation|spliceosomal A2-1 complex biosynthesis|spliceosomal B1 complex biosynthesis|cis assembly of U2-type pre-catalytic spliceosome|formation of spliceosomal B1 complex|formation of spliceosomal A2-1 complex|spliceosomal A2-1 complex formation					Note that this step represents formation of the A2-1 complex (yeast) or the B1 complex (mammals).						GO:0000361|GO:0000360		biological_process											owl:Class	
GO:0031251	biolink:NamedThing	PAN complex	A complex that possesses poly(A)-specific ribonuclease activity; catalyzes the message-specific shortening of mRNA poly(A) tails. Contains at least two subunits, known as Pan2p and Pan3p in Saccharomyces.	tmpzr1t_l9r_go_relaxed.owl	poly(A) nuclease complex													cellular_component											owl:Class	
GO:0031470	biolink:NamedThing	carboxysome	An organelle consisting of a proteinaceous coat and enzymes for the fixation of CO(2). It augments the concentration of CO(2) in the vicinity of RuBisCO to increase the efficiency of CO(2) fixation under atmospheric conditions.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/19743			Wikipedia:Carboxysome									cellular_component											owl:Class	
GO:0070617	biolink:NamedThing	negative regulation of thiamine diphosphate biosynthetic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of thiamine diphosphate.	tmpzr1t_l9r_go_relaxed.owl	down regulation of thiamine diphosphate biosynthetic process|negative regulation of thiamine diphosphate biosynthesis|negative regulation of thiamine diphosphate anabolism|inhibition of thiamine diphosphate biosynthetic process|negative regulation of thiamine diphosphate formation|downregulation of thiamine diphosphate biosynthetic process|negative regulation of thiamin diphosphate biosynthetic process|down-regulation of thiamine diphosphate biosynthetic process|negative regulation of thiamine diphosphate synthesis							mah	2009-04-29T03:39:48Z					biological_process											owl:Class	
GO:0043616	biolink:NamedThing	keratinocyte proliferation	The multiplication or reproduction of keratinocytes, resulting in the expansion of a cell population. Keratinocytes are epidermal cells which synthesize keratin and undergo a characteristic change as they move upward from the basal layers of the epidermis to the cornified (horny) layer of the skin.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0032626	biolink:NamedThing	interleukin-22 production	The appearance of interleukin-22 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	tmpzr1t_l9r_go_relaxed.owl	ILTIF production|ZCYTO18 production|IL22 production|interleukin-22 biosynthetic process|interleukin-22 secretion|IL-22 production											GO:0042239|GO:0072620		biological_process											owl:Class	
GO:0098921	biolink:NamedThing	retrograde trans-synaptic signaling by endocannabinoid	Cell-cell signaling from postsynapse to presynapse, across the synaptic cleft, mediated by an  endocannabinoid ligand.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0005021	biolink:NamedThing	vascular endothelial growth factor-activated receptor activity	Combining with a vascular endothelial growth factor (VEGF) and transmitting the signal across the plasma membrane to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	VEGF receptor activity|VEGF-A-activated receptor activity|VEGF-E-activated receptor activity|VEGF-B-activated receptor activity|vascular endothelial growth factor E-activated receptor activity|VEGF-D-activated receptor activity|VEGF-C-activated receptor activity|VEGF-activated receptor activity|VEGFR activity|vascular endothelial growth factor receptor activity					Note that this term represents an activity and not a gene product, and should only be used when the receptor binds the ligand VEGF. For receptors that bind other growth factors, consider annotating to terms under 'transmembrane signaling receptor activity ; GO:0004888.						GO:0036328|GO:0036330|GO:0036326|GO:0036327|GO:0036329		molecular_function											owl:Class	
GO:0031443	biolink:NamedThing	fast-twitch skeletal muscle fiber contraction	A process in which force is generated within fast-twitch skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The fast-twitch skeletal muscle is characterized by fast time parameters, high force development and fatiguability.	tmpzr1t_l9r_go_relaxed.owl	fast-twitch skeletal muscle fibre contraction|fast-twitch skeletal fiber contraction|fast-twitch skeletal myofibre contraction|fast-twitch skeletal myofiber contraction|fast-twitch skeletal fibre contraction													biological_process											owl:Class	
GO:0016562	biolink:NamedThing	protein import into peroxisome matrix, receptor recycling	The process in which peroxisome targeting sequence receptors dissociates from cargo proteins and are returned to the cytosol.	tmpzr1t_l9r_go_relaxed.owl	peroxisome matrix protein import, receptor recycling|protein transport into peroxisome matrix, receptor recycling|receptor recycling during protein transport into peroxisome matrix|PTS receptor recycling|receptor recycling during peroxisome matrix protein import|peroxisome receptor recycling|receptor recycling during protein import into peroxisome matrix													biological_process											owl:Class	
GO:1901459	biolink:NamedThing	positive regulation of response to acetate	Any process that activates or increases the frequency, rate or extent of response to acetate.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of response to acetate|up regulation of response to acetate|activation of response to acetate|upregulation of response to acetate							tt	2012-10-02T14:26:34Z					biological_process											owl:Class	
GO:0006634	biolink:NamedThing	hexadecanal biosynthetic process	The chemical reactions and pathways resulting in the formation of hexadecanal, the C16 straight chain aldehyde.	tmpzr1t_l9r_go_relaxed.owl	hexadecanal formation|palmitaldehyde biosynthetic process|hexadecanal biosynthesis|palmitaldehyde biosynthesis|hexadecanal anabolism|hexadecanal synthesis													biological_process											owl:Class	
GO:0042884	biolink:NamedThing	microcin transport	The directed movement of microcin, a class of glycine-rich, bactericidal peptides (antibiotics) produced by some enteric bacteria, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0019073	biolink:NamedThing	viral DNA genome packaging	The packing of viral DNA into a capsid.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0035235	biolink:NamedThing	ionotropic glutamate receptor signaling pathway	A series of molecular signals initiated by glutamate binding to a glutamate receptor on the surface of the target cell, followed by the movement of ions through a channel in the receptor complex. Ends with regulation of a downstream cellular process, e.g. transcription.	tmpzr1t_l9r_go_relaxed.owl	ionotropic glutamate receptor signalling pathway													biological_process											owl:Class	
GO:0050674	biolink:NamedThing	urothelial cell proliferation	The multiplication or reproduction of urothelial cells, resulting in the expansion of a cell population. Urothelial cells make up a layer of transitional epithelium in the wall of the bladder, ureter, and renal pelvis, external to the lamina propria.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0038162	biolink:NamedThing	erythropoietin-mediated signaling pathway	A series of molecular signals initiated by the binding of erythropoietin (EPO) to the erythropoietin receptor (EPO-R) on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.	tmpzr1t_l9r_go_relaxed.owl	EPO-R signaling pathway|erythropoietin receptor signaling pathway							bf	2012-05-14T02:28:38Z					biological_process											owl:Class	
GO:0021842	biolink:NamedThing	chemorepulsion involved in interneuron migration from the subpallium to the cortex	The creation and reception of signals that result in the movement of interneurons away from the signal during migration from the subpallium to the cortex.	tmpzr1t_l9r_go_relaxed.owl	negative chemotaxis involved in interneuron migration from the subpallium to the cortex													biological_process											owl:Class	
GO:0003839	biolink:NamedThing	gamma-glutamylcyclotransferase activity	Catalysis of the reaction: (5-L-glutamyl)-L-amino acid = 5-oxoproline + L-amino acid.	tmpzr1t_l9r_go_relaxed.owl	gamma-glutamyl-amino acid cyclotransferase activity|(5-L-glutamyl)-L-amino-acid 5-glutamyltransferase (cyclizing)|L-glutamic cyclase activity|gamma-L-glutamylcyclotransferase activity				Reactome:R-HSA-6785928|RHEA:20505|Reactome:R-HSA-1247922|EC:4.3.2.9|MetaCyc:GAMMA-GLUTAMYLCYCLOTRANSFERASE-RXN									molecular_function											owl:Class	
GO:0043867	biolink:NamedThing	7-cyano-7-deazaguanine tRNA-ribosyltransferase activity	Catalysis of the reaction: tRNA guanine + 7-cyano-7-deazaguanine = tRNA 7-cyano-7-deazaguanine + guanine.	tmpzr1t_l9r_go_relaxed.owl	archaeosine tRNA-ribosyltransferase activity|archaeal tRNA-guanine transglycosylase activity|TgtA													molecular_function											owl:Class	
GO:1900096	biolink:NamedThing	negative regulation of dosage compensation by inactivation of X chromosome	Any process that stops, prevents or reduces the frequency, rate or extent of dosage compensation, by inactivation of X chromosome.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of chromosome inactivation|down regulation of dosage compensation, by inactivation of X chromosome|negative regulation of X chromosome inactivation|down regulation of chromosome inactivation|downregulation of dosage compensation, by inactivation of X chromosome|down-regulation of X chromosome inactivation|downregulation of Barr body formation|down regulation of X chromosome inactivation|down-regulation of chromosome inactivation|inhibition of Barr body formation|downregulation of chromosome inactivation|inhibition of X chromosome inactivation|downregulation of X chromosome inactivation|inhibition of chromosome inactivation|inhibition of dosage compensation, by inactivation of X chromosome|down-regulation of Barr body formation|down regulation of Barr body formation|down-regulation of dosage compensation, by inactivation of X chromosome|negative regulation of Barr body formation							hjd	2012-02-14T07:29:49Z					biological_process											owl:Class	
GO:0034469	biolink:NamedThing	Golgi stack lumen	The volume enclosed by any of the membranes of the thin, flattened cisternae that form the central portion of the Golgi complex.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0090611	biolink:NamedThing	ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway	The chemical reactions and pathways resulting in the breakdown of a protein or peptide, via the multivesicular body (MVB) sorting pathway; proteins are sorted into MVBs, and delivered to a lysosome/vacuole for degradation.  This process is independent of ubiquitination.	tmpzr1t_l9r_go_relaxed.owl								tb	2014-10-23T15:27:12Z					biological_process											owl:Class	
GO:0007039	biolink:NamedThing	protein catabolic process in the vacuole	The chemical reactions and pathways resulting in the breakdown of a protein in the vacuole, usually by the action of vacuolar proteases.	tmpzr1t_l9r_go_relaxed.owl	vacuolar protein degradation|vacuolar protein breakdown|vacuolar protein catabolism|vacuolar protein catabolic process													biological_process											owl:Class	
GO:0005892	biolink:NamedThing	acetylcholine-gated channel complex	A homo- or hetero-pentameric protein complex that forms a transmembrane channel through which ions may pass in response to acetylcholine binding.	tmpzr1t_l9r_go_relaxed.owl	nicotinic acetylcholine receptor|nicotinic acetylcholine-gated receptor-channel complex													cellular_component											owl:Class	
GO:2000550	biolink:NamedThing	negative regulation of B cell chemotaxis	Any process that stops, prevents or reduces the frequency, rate or extent of B cell chemotaxis.	tmpzr1t_l9r_go_relaxed.owl								ebc	2011-04-03T07:25:59Z					biological_process											owl:Class	
GO:0004867	biolink:NamedThing	serine-type endopeptidase inhibitor activity	Binds to and stops, prevents or reduces the activity of serine-type endopeptidases, enzymes that catalyze the hydrolysis of nonterminal peptide bonds in a polypeptide chain; a serine residue (and a histidine residue) are at the active center of the enzyme.	tmpzr1t_l9r_go_relaxed.owl	serine protease inhibitor activity|serine proteinase inhibitor activity|serpin activity				Reactome:R-HSA-159005|Reactome:R-HSA-159001|Reactome:R-HSA-158800|Reactome:R-HSA-158795|Reactome:R-HSA-158893									molecular_function											owl:Class	
GO:2001076	biolink:NamedThing	positive regulation of metanephric ureteric bud development	Any process that activates or increases the frequency, rate or extent of metanephric ureteric bud development.	tmpzr1t_l9r_go_relaxed.owl								yaf	2011-09-14T01:11:15Z					biological_process											owl:Class	
GO:0003202	biolink:NamedThing	endocardial cushion to mesenchymal transition involved in cardiac skeleton development	A transition where an endocardial cushion cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell that will give rise to the cardiac skeleton.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-10-08T01:39:57Z					biological_process											owl:Class	
GO:0021735	biolink:NamedThing	dentate nucleus development	The process whose specific outcome is the progression of the dentate nucleus over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0045463	biolink:NamedThing	R8 cell development	The process whose specific outcome is the progression of the R8 photoreceptor over time, from its formation to the mature structure. The R8 photoreceptor is the founding receptor of each ommatidium.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0060574	biolink:NamedThing	intestinal epithelial cell maturation	The developmental process, independent of morphogenetic (shape) change, that is required for a columna/cuboidal epithelial cell of the intestine to attain its fully functional state. A columnar/cuboidal epithelial cell of the intestine mature as they migrate from the intestinal crypt to the villus.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-05-06T08:10:41Z					biological_process											owl:Class	
GO:0098545	biolink:NamedThing	maintenance of protein complex location in cytoplasm	Any process in which a protein complex is maintained in a specific location within the cytoplasm and is prevented from moving elsewhere.	tmpzr1t_l9r_go_relaxed.owl								dos	2013-11-15T20:49:15Z					biological_process											owl:Class	
GO:0031613	biolink:NamedThing	nuclear proteasome regulatory particle, lid subcomplex	The subunits that form the peripheral lid of the regulatory particle of a proteasome located in the nucleus of a cell.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0031598	biolink:NamedThing	nuclear proteasome regulatory particle	The regulatory subcomplex of a proteasome located in the nucleus of a cell.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0035218	biolink:NamedThing	leg disc development	Progression of the leg imaginal disc over time, from its initial formation through to its metamorphosis to form adult structures including the leg, coxa and ventral thoracic pleura.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0003334	biolink:NamedThing	keratinocyte development	The process whose specific outcome is the progression of a keratinocyte over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-11-24T08:55:57Z					biological_process											owl:Class	
GO:0010315	biolink:NamedThing	auxin efflux	The process involved in the transport of auxin out of the cell.	tmpzr1t_l9r_go_relaxed.owl	auxin export													biological_process											owl:Class	
GO:0044339	biolink:NamedThing	canonical Wnt signaling pathway involved in osteoblast differentiation	The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes involved in osteoblast differentiation.	tmpzr1t_l9r_go_relaxed.owl	canonical Wnt receptor signalling pathway involved in osteoblast differentiation|canonical Wnt receptor signaling pathway involved in osteoblast differentiation|canonical Wnt-activated signaling pathway involved in osteoblast differentiation							jl	2010-08-20T03:52:11Z					biological_process											owl:Class	
GO:0035242	biolink:NamedThing	protein-arginine omega-N asymmetric methyltransferase activity	Catalysis of the addition of a second methyl group to methylated peptidyl-arginine. Methylation is on the same terminal nitrogen (omega nitrogen) residue that was previously methylated, resulting in asymmetrical peptidyl-N(omega),N(omega)-dimethylated arginine residues.	tmpzr1t_l9r_go_relaxed.owl	S-adenosyl-L-methionine:[protein]-L-arginine N-methyltransferase ([protein]-Nomega,Nomega-dimethyl-L-arginine-forming)|type I PRMT activity|type I protein arginine methyltransferase activity				RHEA:48096|EC:2.1.1.319|RESID:AA0069|RESID:AA0068	Note that type I protein arginine N-methyltransferase enzymes possess 'protein-arginine omega-N monomethyltransferase activity ; GO:0035241' and 'protein-arginine omega-N asymmetric methyltransferase activity ; GO:0035242'.								molecular_function											owl:Class	
GO:0019919	biolink:NamedThing	peptidyl-arginine methylation, to asymmetrical-dimethyl arginine	The process of methylation of peptidyl-arginine to form peptidyl-N(omega),N(omega)-dimethyl-L-arginine.	tmpzr1t_l9r_go_relaxed.owl	peptidyl-arginine methylation, to unsymmetrical-dimethyl arginine				RESID:AA0068|RESID:AA0069									biological_process											owl:Class	
GO:0001621	biolink:NamedThing	G protein-coupled ADP receptor activity	Combining with ADP and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.	tmpzr1t_l9r_go_relaxed.owl	K101 receptor|ADP-activated nucleotide receptor activity|ADP-activated adenosine receptor activity|platelet ADP receptor activity|ADP receptor activity											GO:0045032		molecular_function											owl:Class	
GO:0039547	biolink:NamedThing	suppression by virus of host TRAF activity	Any process in which a virus stops, prevents, or reduces the activity of a host TRAF (tumor necrosis factor receptor-associated factor) protein. TRAFs are intracellular signal transducers that lie downstream of receptors including RIG-I, MDA-5 and Toll-like receptors (TLR) and transfer the signal to other intracellular signaling components.	tmpzr1t_l9r_go_relaxed.owl	inhibition of host TRAFs by virus					This term is for annotation of viral proteins that counteract the host anti-viral innate immune response.		bf	2012-01-19T03:12:15Z					biological_process											owl:Class	
GO:0007504	biolink:NamedThing	larval fat body development	The process whose specific outcome is the progression of the larval fat body over time, from its formation to the mature structure. The larval fat body consists of a bilaterally symmetrical monolayer of cells lying between the gut and the muscles of the body wall. As in other tissues of the larva, the cells of the fat body complete their divisions in the embryo and increase in size and ploidy during larval life.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1904170	biolink:NamedThing	regulation of bleb assembly	Any process that modulates the frequency, rate or extent of bleb assembly.	tmpzr1t_l9r_go_relaxed.owl	regulation of cell blebbing							als	2015-04-23T09:32:19Z					biological_process											owl:Class	
GO:0000245	biolink:NamedThing	spliceosomal complex assembly	The aggregation, arrangement and bonding together of a spliceosomal complex, a ribonucleoprotein apparatus that catalyzes nuclear mRNA splicing via transesterification reactions.	tmpzr1t_l9r_go_relaxed.owl	spliceosome assembly													biological_process											owl:Class	
GO:0010458	biolink:NamedThing	exit from mitosis	The cell cycle transition where a cell leaves M phase and enters a new G1 phase. M phase is the part of the mitotic cell cycle during which mitosis and cytokinesis take place.	tmpzr1t_l9r_go_relaxed.owl	mitotic exit|exit from mitotic division													biological_process											owl:Class	
GO:0061180	biolink:NamedThing	mammary gland epithelium development	The process whose specific outcome is the progression of the mammary gland epithelium over time, from its formation to the mature structure. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk.	tmpzr1t_l9r_go_relaxed.owl	breast epithelium development							dph	2010-07-14T08:18:24Z					biological_process											owl:Class	
GO:0032909	biolink:NamedThing	regulation of transforming growth factor beta2 production	Any process that modulates the frequency, rate, or extent of production of transforming growth factor-beta2.	tmpzr1t_l9r_go_relaxed.owl	regulation of transforming growth factor-beta2 production|regulation of TGF-B2 production|regulation of TGFB2 production													biological_process											owl:Class	
GO:0045781	biolink:NamedThing	negative regulation of cell budding	Any process that stops, prevents, or reduces the frequency, rate or extent of cell budding.	tmpzr1t_l9r_go_relaxed.owl	down regulation of cell budding|downregulation of cell budding|negative regulation of budding|inhibition of cell budding|down-regulation of cell budding													biological_process											owl:Class	
GO:0051906	biolink:NamedThing	maintenance of pigment granule location	Any process in which a pigment granule is maintained in a location and prevented from moving elsewhere.	tmpzr1t_l9r_go_relaxed.owl	maintenance of pigment granule localization													biological_process											owl:Class	
GO:1905251	biolink:NamedThing	epidermal growth factor receptor signaling pathway involved in heart process	Any epidermal growth factor receptor signaling pathway that is involved in heart process.	tmpzr1t_l9r_go_relaxed.owl	ERBB1 signaling pathway involved in heart process|EGF receptor signaling pathway involved in cardiac process|EGF receptor signalling pathway involved in cardiac process|epidermal growth factor receptor signalling pathway involved in cardiac process|EGF receptor signalling pathway involved in heart process|EGFR signaling pathway involved in heart process|epidermal growth factor receptor signalling pathway involved in heart process|receptor tyrosine-protein kinase erbB-1 signaling pathway involved in cardiac process|EGFR signaling pathway involved in cardiac process|ERBB1 signaling pathway involved in cardiac process|receptor tyrosine-protein kinase erbB-1 signaling pathway involved in heart process|epidermal growth factor receptor signaling pathway involved in cardiac process|EGF receptor signaling pathway involved in heart process							bc	2016-06-10T09:20:54Z					biological_process											owl:Class	
GO:0044644	biolink:NamedThing	envenomation resulting in negative regulation of complement activation, alternative pathway in other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant negative regulation of complement activation via the alternative pathway in the bitten/stung organism.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-07-11T12:35:11Z					biological_process											owl:Class	
GO:0005068	biolink:NamedThing	transmembrane receptor protein tyrosine kinase adaptor activity	The binding activity of a molecule that brings together a transmembrane receptor protein tyrosine kinase and one or more other molecules, permitting them to function in a coordinated way.	tmpzr1t_l9r_go_relaxed.owl	transmembrane receptor protein tyrosine kinase docking protein activity|transmembrane receptor protein tyrosine kinase adaptor protein activity											GO:0005069		molecular_function											owl:Class	
GO:0003024	biolink:NamedThing	baroreceptor detection of decreased arterial stretch	The series of events by which a decrease in diameter of an artery is detected and converted to a molecular signal.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1904908	biolink:NamedThing	negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric	Any process that stops, prevents or reduces the frequency, rate or extent of maintenance of mitotic sister chromatid cohesion, telomeric.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of maintenance of mitotic sister chromatin cohesion at telomere|down regulation of maintenance of sister chromatin cohesion at telomere at mitosis|down regulation of maintenance of mitotic sister chromatid cohesion, telomeric|inhibition of maintenance of mitotic sister chromatin cohesion at telomere|downregulation of maintenance of sister chromatin cohesion at telomere at mitosis|inhibition of maintenance of sister chromatin cohesion at telomere at mitosis|downregulation of maintenance of telomeric mitotic sister chromatin cohesion|negative regulation of maintenance of mitotic sister chromatin cohesion at telomere|negative regulation of maintenance of telomeric mitotic sister chromatin cohesion|down-regulation of maintenance of sister chromatin cohesion at telomere at mitosis|down regulation of maintenance of telomeric mitotic sister chromatin cohesion|downregulation of maintenance of mitotic sister chromatid cohesion, telomeric|down-regulation of maintenance of mitotic sister chromatid cohesion, telomeric|inhibition of maintenance of mitotic sister chromatid cohesion, telomeric|down regulation of maintenance of mitotic sister chromatin cohesion at telomere|downregulation of maintenance of mitotic sister chromatin cohesion at telomere|down-regulation of maintenance of telomeric mitotic sister chromatin cohesion|inhibition of maintenance of telomeric mitotic sister chromatin cohesion|negative regulation of maintenance of sister chromatin cohesion at telomere at mitosis							rph	2016-01-19T10:30:36Z					biological_process											owl:Class	
GO:0000239	biolink:NamedThing	pachytene	The cell cycle phase which follows zygotene during prophase I of meiosis, and during which crossing over occurs between a chromatid in one partner and another chromatid in the homologous chromosome.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Pachytene|Wikipedia:Meiosis#Pachytene	Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).								biological_process											owl:Class	
GO:0009359	biolink:NamedThing	type II site-specific deoxyribonuclease complex	A protein complex that functions as an endonuclease to cleave DNA at or near a specific recognition site, when that site is unmethylated. These complexes may be dimers or tetramers; it is also possible for the endonuclease to be in a complex with the corresponding methyltransferase that methylates the recognition site. DNA restriction systems such as this are used by bacteria to defend against phage and other foreign DNA that may enter a cell.	tmpzr1t_l9r_go_relaxed.owl	type II restriction enzyme complex													cellular_component											owl:Class	
GO:0004902	biolink:NamedThing	granulocyte colony-stimulating factor receptor activity	Combining with granulocyte colony-stimulating factor (G-CSF) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	G-CSF receptor activity|granulocyte colony stimulating factor receptor activity|CSF3R											GO:0030524		molecular_function											owl:Class	
GO:0038158	biolink:NamedThing	granulocyte colony-stimulating factor signaling pathway	A series of molecular signals initiated by the binding of the cytokine granulocyte colony-stimulating factor (G-CSF) to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. G-CSF binds to the receptor (CSF3R).	tmpzr1t_l9r_go_relaxed.owl	granulocyte colony-stimulating factor signalling pathway|CSF3 signaling pathway|granulocyte colony-stimulating factor receptor signaling pathway|G-CSF receptor signaling pathway|G-CSF signaling pathway							bf	2012-05-14T01:30:28Z					biological_process											owl:Class	
GO:0050946	biolink:NamedThing	positive regulation of xanthophore differentiation	Any process that activates or increases the frequency, rate or extent of xanthophore differentiation.	tmpzr1t_l9r_go_relaxed.owl	up regulation of xanthophore differentiation|stimulation of xanthophore differentiation|activation of xanthophore differentiation|up-regulation of xanthophore differentiation|upregulation of xanthophore differentiation					Note that this term refers to xanthophores in the sense of specialized pigment-producing cells, and should not be confused with the cellular component term 'xanthophore ; GO:0031633', which refers to a subcellular structure.								biological_process											owl:Class	
GO:2000204	biolink:NamedThing	negative regulation of ribosomal large subunit export from nucleus	Any process that stops, prevents, or reduces the frequency, rate or extent of ribosomal large subunit export from nucleus.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of ribosomal large subunit export from cell nucleus|negative regulation of 60S ribosomal subunit export from nucleus|negative regulation of ribosomal large subunit-nucleus export|negative regulation of ribosomal large subunit transport from nucleus to cytoplasm|negative regulation of ribosomal large subunit export out of nucleus|negative regulation of 50S ribosomal subunit export from nucleus							mah	2010-10-26T10:52:39Z					biological_process											owl:Class	
GO:1904861	biolink:NamedThing	excitatory synapse assembly	The aggregation, arrangement and bonding together of a set of components to form an excitatory synapse.	tmpzr1t_l9r_go_relaxed.owl	excitatory synapse formation							bf	2015-12-17T10:31:26Z					biological_process											owl:Class	
GO:0002043	biolink:NamedThing	blood vessel endothelial cell proliferation involved in sprouting angiogenesis	The multiplication or reproduction of blood vessel endothelial cells, resulting in the expansion of a cell population contributing to sprouting angiogenesis.	tmpzr1t_l9r_go_relaxed.owl	blood vessel endothelial cell proliferation during sprouting angiogenesis													biological_process											owl:Class	
GO:0014839	biolink:NamedThing	myoblast migration involved in skeletal muscle regeneration	The process in which a myoblast migrates along an entire fiber to the site of injury. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.	tmpzr1t_l9r_go_relaxed.owl	mononucleate cell migration involved in skeletal muscle regeneration													biological_process											owl:Class	
GO:0042466	biolink:NamedThing	chemokinesis	A response by a motile cell to a soluble chemical that involves an increase or decrease in speed (positive or negative orthokinesis) or of frequency of movement or a change in the frequency or magnitude of turning behavior (klinokinesis).	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Chemokinesis									biological_process											owl:Class	
GO:0048932	biolink:NamedThing	myelination of posterior lateral line nerve axons	The formation of compact myelin sheaths around the axons of the posterior lateral line nerve.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0048942	biolink:NamedThing	posterior lateral line nerve glial cell morphogenesis involved in differentiation	The process in which the structures of a glial cell in the posterior lateral line nerve are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a glial cell in the posterior lateral line nerve.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0060174	biolink:NamedThing	limb bud formation	The process pertaining to the initial formation of a limb bud from unspecified parts. This process begins with the formation of a local condensation of mesenchyme cells within the prospective limb field, and ends when a limb bud is recognizable.	tmpzr1t_l9r_go_relaxed.owl	limbbud formation|limb formation													biological_process											owl:Class	
GO:0035108	biolink:NamedThing	limb morphogenesis	The process in which the anatomical structures of a limb are generated and organized. A limb is a paired appendage of a tetrapod used for locomotion or grasping.	tmpzr1t_l9r_go_relaxed.owl	limb bud morphogenesis													biological_process											owl:Class	
GO:0070092	biolink:NamedThing	regulation of glucagon secretion	Any process that modulates the frequency, rate or extent of the regulated release of glucagon.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0036241	biolink:NamedThing	glutamate catabolic process to 4-hydroxybutyrate	The chemical reactions and pathways resulting in the breakdown of glutamate into 4-hydroxybutyrate.	tmpzr1t_l9r_go_relaxed.owl	glutamate degradation to 4-hydroxybutyrate					In the catabolism of glutamate in mammals, succinate semialdehyde is converted to succinate (see GO:0006540). Plants can utilize an alternative route, converting succinic semialdehyde to 4-hydroxybutyrate using gamma-hydroxybutyrate dehydrogenase.		bf	2012-05-23T02:17:05Z					biological_process											owl:Class	
GO:0047577	biolink:NamedThing	4-hydroxybutyrate dehydrogenase activity	Catalysis of the reaction: 4-hydroxybutanoate + NAD(+) = H(+) + NADH + succinate semialdehyde.	tmpzr1t_l9r_go_relaxed.owl	gamma-hydroxybutyrate dehydrogenase activity|4-hydroxybutanoate:NAD+ oxidoreductase activity				MetaCyc:4-HYDROXYBUTYRATE-DEHYDROGENASE-RXN|EC:1.1.1.61|RHEA:23948|KEGG_REACTION:R01644									molecular_function											owl:Class	
GO:0002089	biolink:NamedThing	lens morphogenesis in camera-type eye	The process in which the anatomical structures of the lens are generated and organized. The lens is a transparent structure in the eye through which light is focused onto the retina. An example of this process is found in Mus musculus.	tmpzr1t_l9r_go_relaxed.owl	lens morphogenesis|lens morphogenesis in camera-style eye													biological_process											owl:Class	
GO:0045466	biolink:NamedThing	R7 cell differentiation	The process in which a relatively unspecialized cell acquires the specialized features of the R7 photoreceptor.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1905618	biolink:NamedThing	positive regulation of miRNA-mediated gene silencing by inhibition of translation	Any process that activates or increases the frequency, rate or extent of miRNA-mediated gene silencing by inhibition of translation.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of inhibition of translation involved in gene silencing by miRNA|up-regulation of miRNA-mediated gene silencing, negative regulation of translation|up-regulation of miRNA mediated inhibition of translation|positive regulation of gene silencing by miRNA, negative regulation of translation|activation of down-regulation of translation involved in gene silencing by miRNA|positive regulation of miRNA-mediated gene silencing, negative regulation of translation|upregulation of down regulation of translation involved in gene silencing by miRNA|up regulation of down regulation of translation involved in gene silencing by miRNA|activation of inhibition of translation involved in gene silencing by miRNA|positive regulation of miRNA mediated inhibition of translation|activation of gene silencing by miRNA, negative regulation of translation|up regulation of gene silencing by miRNA, negative regulation of translation|positive regulation of downregulation of translation involved in gene silencing by miRNA|up regulation of miRNA-mediated gene silencing, negative regulation of translation|upregulation of miRNA-mediated gene silencing, negative regulation of translation|upregulation of negative regulation of translation involved in gene silencing by microRNA|up-regulation of downregulation of translation involved in gene silencing by miRNA|up-regulation of down regulation of translation involved in gene silencing by miRNA|up-regulation of gene silencing by miRNA, negative regulation of translation|up regulation of downregulation of translation involved in gene silencing by miRNA|up-regulation of down-regulation of translation involved in gene silencing by miRNA|upregulation of gene silencing by miRNA, negative regulation of translation|up-regulation of negative regulation of translation involved in gene silencing by microRNA|upregulation of inhibition of translation involved in gene silencing by miRNA|up regulation of negative regulation of translation involved in gene silencing by microRNA|activation of negative regulation of translation involved in gene silencing by microRNA|positive regulation of negative regulation of translation involved in gene silencing by microRNA|up regulation of miRNA mediated inhibition of translation|positive regulation of down regulation of translation involved in gene silencing by miRNA|positive regulation of down-regulation of translation involved in gene silencing by miRNA|upregulation of downregulation of translation involved in gene silencing by miRNA|upregulation of miRNA mediated inhibition of translation|activation of down regulation of translation involved in gene silencing by miRNA|positive regulation of inhibition of translation involved in gene silencing by miRNA|activation of miRNA-mediated gene silencing, negative regulation of translation|activation of miRNA mediated inhibition of translation|up regulation of down-regulation of translation involved in gene silencing by miRNA|up regulation of inhibition of translation involved in gene silencing by miRNA|activation of downregulation of translation involved in gene silencing by miRNA|upregulation of down-regulation of translation involved in gene silencing by miRNA	https://github.com/geneontology/go-ontology/issues/22389						bc	2016-10-28T11:48:04Z					biological_process											owl:Class	
GO:0021692	biolink:NamedThing	cerebellar Purkinje cell layer morphogenesis	The process in which the anatomical structure of the cerebellar Purkinje cell layer is generated and organized. The Purkinje cell layer lies just underneath the molecular layer of the cerebellar cortex. It contains the neuronal cell bodies of the Purkinje cells that are arranged side by side in a single layer. Candelabrum interneurons are vertically oriented between the Purkinje cells. Purkinje neurons are inhibitory and provide the output of the cerebellar cortex through axons that project into the white matter. Extensive dendritic trees from the Purkinje cells extend upward in a single plane into the molecular layer where they synapse with parallel fibers of granule cells.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0031564	biolink:NamedThing	transcription antitermination	Regulation of transcription by a mechanism that allows RNA polymerase to continue transcription beyond termination site(s).	tmpzr1t_l9r_go_relaxed.owl	transcriptional readthrough													biological_process											owl:Class	
GO:2000621	biolink:NamedThing	regulation of DNA replication termination	Any process that modulates the frequency, rate or extent of DNA replication termination.	tmpzr1t_l9r_go_relaxed.owl								pr	2011-04-18T03:26:23Z					biological_process											owl:Class	
GO:0003983	biolink:NamedThing	UTP:glucose-1-phosphate uridylyltransferase activity	Catalysis of the reaction: alpha-D-glucose 1-phosphate + UTP = diphosphate + UDP-D-glucose.	tmpzr1t_l9r_go_relaxed.owl	UTP:alpha-D-glucose-1-phosphate uridylyltransferase activity|glucose-1-phosphate uridylyltransferase activity|UDPG pyrophosphorylase activity|UDP-glucose pyrophosphorylase activity|UDPG phosphorylase activity|UDP-glucose diphosphorylase activity|UDP glucose pyrophosphorylase activity|uridine diphosphoglucose pyrophosphorylase activity|uridine-diphosphate glucose pyrophosphorylase activity|uridine 5'-diphosphoglucose pyrophosphorylase activity|UTP-glucose-1-phosphate uridylyltransferase activity|uridine diphosphate-D-glucose pyrophosphorylase activity				EC:2.7.7.9|Reactome:R-HSA-70286|MetaCyc:GLUC1PURIDYLTRANS-RXN|RHEA:19889|KEGG_REACTION:R00289									molecular_function											owl:Class	
GO:0060940	biolink:NamedThing	epithelial to mesenchymal transition involved in cardiac fibroblast development	A transition where an epicardial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell that will mature into a cardiac fibroblast.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-09-29T01:32:36Z					biological_process											owl:Class	
GO:0032832	biolink:NamedThing	regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response	Any process that modulates the frequency, rate or extent of differentiation of CD4-positive, CD25-positive, alpha-beta regulatory T cells as part of an immune response.	tmpzr1t_l9r_go_relaxed.owl	regulation of CD4-positive, CD25-positive, alpha-beta regulatory T-cell differentiation during immune response|regulation of CD4-positive, CD25-positive, alpha-beta regulatory T lymphocyte differentiation during immune response|regulation of CD4-positive, CD25-positive, alpha-beta regulatory T-lymphocyte differentiation during immune response|regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell development involved in immune response|regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation during immune response					Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.								biological_process											owl:Class	
GO:0002298	biolink:NamedThing	CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response	The process in which an antigenically naive CD4-positive, alpha-beta T cell acquires the specialized features of a CD4-positive, CD25-positive, alpha-beta regulatory T cell as part of an immune response.	tmpzr1t_l9r_go_relaxed.owl	CD4-positive, CD25-positive, alpha-beta T cell development involved in immune response|CD4-positive, CD25-positive, alpha-beta regulatory T lymphocyte differentiation during immune response|CD4-positive, CD25-positive, alpha-beta regulatory T-cell differentiation during immune response|CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation during immune response|CD4-positive, CD25-positive, alpha-beta regulatory T-lymphocyte differentiation during immune response					Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.								biological_process											owl:Class	
GO:0004169	biolink:NamedThing	dolichyl-phosphate-mannose-protein mannosyltransferase activity	Catalysis of the reaction: dolichyl phosphate D-mannose + protein = dolichyl phosphate + O-D-mannosylprotein.	tmpzr1t_l9r_go_relaxed.owl	dolichol phosphomannose-protein mannosyltransferase activity|O-glycoside mannosyltransferase|dolichyl-phosphate-D-mannose:protein O-D-mannosyltransferase activity|protein O-D-mannosyltransferase activity|protein O-mannosyltransferase activity|dolichyl-phosphate-mannose-protein O-mannosyltransferase activity				Reactome:R-HSA-5615604|MetaCyc:2.4.1.109-RXN|EC:2.4.1.109|Reactome:R-HSA-5615637|Reactome:R-HSA-5615556	Note that this activity has never been observed in green plants. However, N- and C-mannosylation may occur in these species; see figure 1 in PMID:21558543.								molecular_function											owl:Class	
GO:0048896	biolink:NamedThing	lateral line nerve glial cell migration	The movement of a glial cell along the axons in a lateral line nerve.	tmpzr1t_l9r_go_relaxed.owl	glial cell migration in lateral line nerve													biological_process											owl:Class	
GO:0075194	biolink:NamedThing	positive regulation of haustorium mother cell formation	Any process that activates or increases the frequency, rate or extent of symbiont haustorium mother cell formation. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of haustorium mother cell formation on or near host					Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products from the symbiont involved in this process.								biological_process											owl:Class	
GO:0043029	biolink:NamedThing	T cell homeostasis	The process of regulating the proliferation and elimination of T cells such that the total number of T cells within a whole or part of an organism is stable over time in the absence of an outside stimulus.	tmpzr1t_l9r_go_relaxed.owl	T-cell homeostasis|T-lymphocyte homeostasis|T lymphocyte homeostasis					Note that this term represents the return of T cell levels to stable numbers following an immune response as well as the proliferation and elimination of T cells required to maintain stable numbers in the absence of an outside stimulus.								biological_process											owl:Class	
GO:0044694	biolink:NamedThing	pore-mediated entry of viral genome into host cell	Injection by a non-enveloped virus of the viral genome into the host cytoplasm through creation of a pore or channel in the host cell membrane(s). Usually mediated by a viral pore-forming peptide associated with the viral capsid or bacteriophage tail.	tmpzr1t_l9r_go_relaxed.owl	viral genome delivery via icosahedral vertex|viral genome translocation|membrane puncture-mediated penetration of viral genome into host cell|viral pore-forming protein|viral entry via genome injection|pore-mediated penetration of viral genome into host cell				VZ:979	This mechanism is used by animal viruses such as poliovirus. Various tailed bacteriophages also carry specialized proteins which open a pore or a channel in the host membrane(s) to allow genome delivery into host cytoplasm.		jl	2012-08-16T11:08:02Z					biological_process											owl:Class	
GO:0002114	biolink:NamedThing	interleukin-33 receptor activity	Combining with interleukin-33 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	IL-33R|IL-33 receptor activity													molecular_function											owl:Class	
GO:0038172	biolink:NamedThing	interleukin-33-mediated signaling pathway	A series of molecular signals initiated by the binding of interleukin-33 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.	tmpzr1t_l9r_go_relaxed.owl	IL-33-mediated signaling pathway|IL33 signaling pathway|interleukin-33-mediated signalling pathway|interleukin-33 signaling pathway							bf	2012-06-12T10:57:35Z					biological_process											owl:Class	
GO:0021968	biolink:NamedThing	corticospinal neuron axon guidance through the internal capsule	The process in which the migration of an axon growth cone of a pyramidal cell that is part of the corticospinal tract is directed after exiting the cerebral cortex through the internal capsule in response to a combination of attractive and repulsive cues.	tmpzr1t_l9r_go_relaxed.owl	corticospinal neuron axon pathfinding through the internal capsule													biological_process											owl:Class	
GO:0140709	biolink:NamedThing	Frizzled Nuclear Import pathway	The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by internalization and cleavage of the frizzled receptor to yeild a C-terminal fragment that is imported into the nucleus. The frizzled C-terminal fragment is incorporated into large ribonucleoprotein particles and stimulates their egress via nuclear budding.	tmpzr1t_l9r_go_relaxed.owl	FNI|Frizzled Nuclear Import Wnt Pathway	https://github.com/geneontology/go-ontology/issues/21483						pg	2021-09-08T09:11:25Z					biological_process											owl:Class	
GO:0033147	biolink:NamedThing	negative regulation of intracellular estrogen receptor signaling pathway	Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of an intracellular estrogen receptor signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of estrogen receptor signaling pathway|negative regulation of estrogen receptor signalling pathway													biological_process											owl:Class	
GO:0072006	biolink:NamedThing	nephron development	The process whose specific outcome is the progression of the nephron over time, from its formation to the mature structure. A nephron is the functional unit of the kidney.	tmpzr1t_l9r_go_relaxed.owl	nephrogenesis							mah	2010-01-25T01:37:16Z					biological_process											owl:Class	
GO:0010260	biolink:NamedThing	animal organ senescence	The process that occurs in an animal organ near the end of its active life that is associated with the dismantling of cell components and membranes, and an overall decline in metabolism.	tmpzr1t_l9r_go_relaxed.owl												GO:0010261		biological_process											owl:Class	
GO:0009941	biolink:NamedThing	chloroplast envelope	The double lipid bilayer enclosing the chloroplast and separating its contents from the rest of the cytoplasm; includes the intermembrane space.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0010321	biolink:NamedThing	regulation of vegetative phase change	Any process that modulates the frequency, rate or extent of vegetative phase change. Vegetative phase change is the set of post-embryonic processes involved in the transition of a plant from a juvenile phase of vegetative development to an adult phase of vegetative development.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0015467	biolink:NamedThing	G-protein activated inward rectifier potassium channel activity	Enables the transmembrane transfer of a potassium ion by an inwardly-rectifying voltage-gated channel, where the inward rectification is due to a voltage-dependent block of the channel pore by a G protein. An inwardly rectifying current-voltage relation is one where at any given driving force the inward flow of K+ ions exceeds the outward flow for the opposite driving force.	tmpzr1t_l9r_go_relaxed.owl	G-protein-activated inward rectifier potassium channel activity|G protein activated inward rectifier potassium channel activity|G protein enhanced inward rectifier potassium channel activity|G-protein enhanced inward rectifier potassium channel activity|G-protein-enhanced inward rectifier potassium channel activity				Reactome:R-HSA-1013020							GO:0015273		molecular_function											owl:Class	
GO:0002318	biolink:NamedThing	myeloid progenitor cell differentiation	The process in which a precursor cell type acquires the specialized features of a myeloid progenitor cell. Myeloid progenitor cells include progenitor cells for any of the myeloid lineages.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0072288	biolink:NamedThing	metanephric proximal tubule morphogenesis	The process in which the anatomical structures of a metanephric proximal tubule are generated and organized. The metanephric proximal tubule is a metanephric nephron tubule that connects Bowman's capsule to the descending thin limb of the loop of Henle in the metanephros. It has a brush border epithelial morphology.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-04-09T03:42:03Z					biological_process											owl:Class	
GO:1990031	biolink:NamedThing	pinceau fiber	Dense plexus formed by the descending collaterals of cerebellar basket cells that wrap around a Purkinje cell axonal initial segment.	tmpzr1t_l9r_go_relaxed.owl					NIF_Subcellular:sao109906988			pr	2013-02-07T12:56:50Z					cellular_component											owl:Class	
GO:0015227	biolink:NamedThing	acyl carnitine transmembrane transporter activity	Enables the transfer of acyl carnitine from one side of a membrane to the other. Acyl carnitine is the condensation product of a carboxylic acid and carnitine and is the transport form for a fatty acid crossing the mitochondrial membrane.	tmpzr1t_l9r_go_relaxed.owl	acylcarnitine transporter activity				Reactome:R-HSA-200424									molecular_function											owl:Class	
GO:0003404	biolink:NamedThing	optic vesicle morphogenesis	The developmental process pertaining to the formation and shaping of the optic vesicle. This process begins with the specific processes that contribute to the appearance of the vesicle and ends when the vesicle has evaginated. The optic vesicle is the evagination of neurectoderm that precedes formation of the optic cup.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-12-21T01:54:34Z					biological_process											owl:Class	
GO:0031069	biolink:NamedThing	hair follicle morphogenesis	The process in which the anatomical structures of the hair follicle are generated and organized.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0048730	biolink:NamedThing	epidermis morphogenesis	The process in which the anatomical structures of the epidermis are generated and organized. The epidermis is the outer epithelial layer of an animal, it may be a single layer that produces an extracellular material (e.g. the cuticle of arthropods) or a complex stratified squamous epithelium, as in the case of many vertebrate species.	tmpzr1t_l9r_go_relaxed.owl	hypodermis morphogenesis													biological_process											owl:Class	
GO:0046878	biolink:NamedThing	positive regulation of saliva secretion	Any process that activates or increases the frequency, rate or extent of the regulated release of saliva.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of saliva secretion|upregulation of saliva secretion|up regulation of saliva secretion|activation of saliva secretion|stimulation of saliva secretion													biological_process											owl:Class	
GO:0060931	biolink:NamedThing	sinoatrial node cell development	The process whose specific outcome is the progression of a sinoatrial (SA) node cell over time, from its formation to the mature state. SA node cells are pacemaker cells that are found in the sinoatrial node.	tmpzr1t_l9r_go_relaxed.owl	sinus node cell development|SAN cell development|SA node cell development							dph	2009-09-29T12:05:47Z					biological_process											owl:Class	
GO:0048728	biolink:NamedThing	proboscis development	The process whose specific outcome is the progression of the proboscis over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl												GO:0016349		biological_process											owl:Class	
GO:0015152	biolink:NamedThing	glucose-6-phosphate transmembrane transporter activity	Enables the transfer of glucose-6-phosphate from one side of a membrane to the other. Glucose-6-phosphate is a monophosphorylated derivative of glucose with the phosphate group attached to C-6.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0048699	biolink:NamedThing	generation of neurons	The process in which nerve cells are generated. This includes the production of neuroblasts and their differentiation into neurons.	tmpzr1t_l9r_go_relaxed.owl	neuron generation													biological_process											owl:Class	
GO:0030970	biolink:NamedThing	retrograde protein transport, ER to cytosol	The directed movement of unfolded or misfolded proteins from the endoplasmic reticulum to the cytosol through the translocon.	tmpzr1t_l9r_go_relaxed.owl	protein retrotranslocation, ER to cytosol|protein dislocation from ER|retrograde protein transport, endoplasmic reticulum to cytosol													biological_process											owl:Class	
GO:0032311	biolink:NamedThing	angiogenin-PRI complex	A stable heterodimer of angiogenin and placental ribonuclease inhibitor; interaction between angiogenin and PRI prevents angiogenin binding to its receptor to stimulate angiogenesis.	tmpzr1t_l9r_go_relaxed.owl	angiogenin-placental ribonuclease inhibitor complex													cellular_component											owl:Class	
GO:1902619	biolink:NamedThing	regulation of microtubule minus-end binding	Any process that modulates the frequency, rate or extent of microtubule minus-end binding.	tmpzr1t_l9r_go_relaxed.owl								tb	2014-01-14T22:17:16Z					biological_process											owl:Class	
GO:0051011	biolink:NamedThing	microtubule minus-end binding	Binding to the minus end of a microtubule.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0000786	biolink:NamedThing	nucleosome	A complex comprised of DNA wound around a multisubunit core and associated proteins, which forms the primary packing unit of DNA into higher order structures.	tmpzr1t_l9r_go_relaxed.owl	cytoplasmic nucleosome|nuclear nucleosome				Wikipedia:Nucleosome							GO:0000788|GO:0005718|GO:0000787		cellular_component											owl:Class	
GO:0008073	biolink:NamedThing	ornithine decarboxylase inhibitor activity	Binds to and stops, prevents or reduces the activity of ornithine decarboxylase.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0004586	biolink:NamedThing	ornithine decarboxylase activity	Catalysis of the reaction: L-ornithine + H(+) = CO(2) + putrescine.	tmpzr1t_l9r_go_relaxed.owl	L-ornithine carboxy-lyase (putrescine-forming)|SpeC|L-ornithine carboxy-lyase activity				RHEA:22964|MetaCyc:ORNDECARBOX-RXN|EC:4.1.1.17|KEGG_REACTION:R00670|Reactome:R-HSA-70692									molecular_function											owl:Class	
GO:0009841	biolink:NamedThing	mitochondrial endopeptidase Clp complex	A Clp endopeptidase complex located in the mitochondrion.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0043366	biolink:NamedThing	beta selection	The process in which successful recombination of a T cell receptor beta chain into a translatable protein coding sequence leads to rescue from apoptosis and subsequent proliferation of an immature T cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0030903	biolink:NamedThing	notochord development	The process whose specific outcome is the progression of the notochord over time, from its formation to the mature structure. The notochord is a mesoderm-derived structure located ventral of the developing nerve cord. In vertebrates, the notochord serves as a core around which other mesodermal cells form the vertebrae. In the most primitive chordates, which lack vertebrae, the notochord persists as a substitute for a vertebral column.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1903473	biolink:NamedThing	positive regulation of mitotic actomyosin contractile ring contraction	Any process that activates or increases the frequency, rate or extent of mitotic actomyosin contractile ring contraction.	tmpzr1t_l9r_go_relaxed.owl	upregulation of cytokinesis, actomyosin ring contraction involved in mitotic cell cycle|up regulation of contractile ring contraction involved in cell cycle cytokinesis involved in mitotic cell cycle|up regulation of mitotic actomyosin contractile ring contraction|up-regulation of mitotic actomyosin contractile ring contraction|positive regulation of mitotic actomyosin contractile ring constriction|up regulation of cytokinesis, actomyosin ring contraction involved in mitotic cell cycle|activation of cytokinesis, actomyosin ring contraction involved in mitotic cell cycle|up-regulation of cytokinesis, actomyosin ring contraction involved in mitotic cell cycle|activation of contractile ring contraction involved in cell cycle cytokinesis involved in mitotic cell cycle|activation of mitotic actomyosin contractile ring contraction|upregulation of mitotic actomyosin contractile ring contraction|positive regulation of contractile ring contraction involved in cell cycle cytokinesis involved in mitotic cell cycle|upregulation of contractile ring contraction involved in cell cycle cytokinesis involved in mitotic cell cycle|up-regulation of contractile ring contraction involved in cell cycle cytokinesis involved in mitotic cell cycle|positive regulation of cytokinesis, actomyosin ring contraction involved in mitotic cell cycle	https://github.com/geneontology/go-ontology/issues/21855						vw	2014-09-23T14:10:46Z					biological_process											owl:Class	
GO:0021541	biolink:NamedThing	ammon gyrus development	The process whose specific outcome is the progression of the ammon gyrus over time, from its formation to the mature structure. The ammon gyrus, often subdivided into the CA1 and CA3 regions, is one of the two interlocking gyri of the hippocampus that is rich in large pyramidal neurons.	tmpzr1t_l9r_go_relaxed.owl	Ammon's horn development|cornu ammonis development													biological_process											owl:Class	
GO:0060017	biolink:NamedThing	parathyroid gland development	The process whose specific outcome is the progression of the parathyroid gland over time, from its formation to the mature structure. The parathyroid gland is an organ specialised for secretion of parathyroid hormone.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0070148	biolink:NamedThing	mitochondrial glutaminyl-tRNA aminoacylation	The process of coupling glutamine to glutaminyl-tRNA in a mitochondrion, catalyzed by glutaminyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0140066	biolink:NamedThing	peptidyl-lysine crotonylation	The crotonylation of a lysine residue in a protein. Crotonyl is the univalent radical CH3-CH=CH-CO- derived from crotonic acid.	tmpzr1t_l9r_go_relaxed.owl								pg	2017-07-20T16:48:58Z					biological_process											owl:Class	
GO:0000349	biolink:NamedThing	generation of catalytic spliceosome for first transesterification step	Formation of a catalytic spliceosome complex ready to perform the first splicing reaction. This occurs by an ATP-dependent conformational change of the pre-catalytic spliceosome.	tmpzr1t_l9r_go_relaxed.owl	formation of catalytic spliceosome for first transesterification step|spliceosomal A2-2 complex biosynthesis|spliceosomal A2-2 complex formation|U2-type catalytic spliceosome formation for first transesterification step|U12-type catalytic spliceosome formation for first transesterification step|spliceosomal C1 complex biosynthesis|spliceosomal C1 complex formation|catalytic spliceosome assembly for first transesterification step					Note that this step represents the formation of the A2-2 complex (yeast) or the C1 complex (mammalian).						GO:0000356|GO:0000357		biological_process											owl:Class	
GO:0075278	biolink:NamedThing	negative regulation of telium development	Any process that stops, prevents, or reduces the frequency, rate or extent of telium development, a process that leads to the formation of a teliospore-bearing sorus of the rust fungi.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0075275	biolink:NamedThing	telium development	The process that leads to the development of a telium, which is a teliospore-bearing sorus of the rust fungi.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0009533	biolink:NamedThing	chloroplast stromal thylakoid	Unstacked thylakoids that connect the grana stacks through the stroma.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0055107	biolink:NamedThing	Golgi to secretory granule transport	The directed movement of proteins from the Golgi to a secretory granule. The secretory granule is a membrane-bounded particle, usually protein, formed in the granular endoplasmic reticulum and the Golgi complex.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0042463	biolink:NamedThing	ocellus photoreceptor cell development	Development of photoreceptors, sensory cells that react to the presence of light, found in the ocellus.	tmpzr1t_l9r_go_relaxed.owl	non-eye photoreceptor development											GO:0001749		biological_process											owl:Class	
GO:0003230	biolink:NamedThing	cardiac atrium development	The process whose specific outcome is the progression of a cardiac atrium over time, from its formation to the mature structure. A cardiac atrium receives blood from a vein and pumps it to a cardiac ventricle.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-10-13T11:02:07Z					biological_process											owl:Class	
GO:0070170	biolink:NamedThing	regulation of tooth mineralization	Any process that modulates the frequency, rate or extent of tooth mineralization, the deposition of calcium salts in tooth structures.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0000145	biolink:NamedThing	exocyst	A protein complex peripherally associated with the plasma membrane that determines where vesicles dock and fuse. At least eight complex components are conserved between yeast and mammals.	tmpzr1t_l9r_go_relaxed.owl	exocyst complex|Sec6/8 complex				Wikipedia:Exocyst									cellular_component											owl:Class	
GO:0120184	biolink:NamedThing	negative regulation of focal adhesion disassembly	Any process that stops, prevents, or reduces the frequency, rate or extent of a focal adhesion into its constituent components.	tmpzr1t_l9r_go_relaxed.owl								krc	2018-07-12T18:30:06Z					biological_process											owl:Class	
GO:0120181	biolink:NamedThing	focal adhesion disassembly	The disaggregation of a focal adhesion into its constituent components. A focal adhesion is a complex of intracellular signaling and structural proteins that provides a structural link between the internal actin cytoskeleton and the ECM, and also functions as a locus of signal transduction activity.	tmpzr1t_l9r_go_relaxed.owl								krc	2018-07-12T17:37:14Z					biological_process											owl:Class	
GO:0004372	biolink:NamedThing	glycine hydroxymethyltransferase activity	Catalysis of the reaction: 5,10-methylenetetrahydrofolate + glycine + H2O = tetrahydrofolate + L-serine.	tmpzr1t_l9r_go_relaxed.owl	serine hydroxymethylase activity|allothreonine aldolase activity|5,10-methylenetetrahydrofolate:glycine hydroxymethyltransferase activity|serine hydroxymethyltransferase activity|serine aldolase activity|L-serine hydroxymethyltransferase activity|serine transhydroxymethylase activity				Reactome:R-HSA-71249|Reactome:R-HSA-200651|RHEA:15481|MetaCyc:GLYOHMETRANS-RXN|EC:2.1.2.1|Reactome:R-HSA-5694137|Reactome:R-HSA-200735									molecular_function											owl:Class	
GO:0030545	biolink:NamedThing	signaling receptor regulator activity	Binds to and modulates the activity of a receptor.	tmpzr1t_l9r_go_relaxed.owl	receptor regulator activity													molecular_function											owl:Class	
GO:0048806	biolink:NamedThing	genitalia development	The process whose specific outcome is the progression of the genitalia over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl	genital development													biological_process											owl:Class	
GO:0007548	biolink:NamedThing	sex differentiation	The establishment of the sex of an organism by physical differentiation.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Sexual_differentiation									biological_process											owl:Class	
GO:0010722	biolink:NamedThing	regulation of ferrochelatase activity	Any process that modulates the frequency, rate or extent of ferrochelatase activity; catalysis of the reaction: protoporphyrin + Fe2+ = protoheme + 2 H+.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0007138	biolink:NamedThing	meiotic anaphase II	The cell cycle phase during which chromosomes separate and migrate towards the poles of the spindle the as part of meiosis II.	tmpzr1t_l9r_go_relaxed.owl						Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).								biological_process											owl:Class	
GO:0035589	biolink:NamedThing	G protein-coupled purinergic nucleotide receptor signaling pathway	The series of molecular signals generated as a consequence of a receptor binding to an extracellular purine nucleotide and transmitting the signal to a heterotrimeric G-protein complex to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	G-protein coupled purinergic nucleotide receptor signaling pathway|P2Y receptor signaling pathway|G-protein coupled purinergic nucleotide receptor signalling pathway							bf	2010-10-22T11:18:59Z					biological_process											owl:Class	
GO:0033601	biolink:NamedThing	positive regulation of mammary gland epithelial cell proliferation	Any process that activates or increases the rate or extent of mammary gland epithelial cell proliferation.	tmpzr1t_l9r_go_relaxed.owl	up regulation of mammary gland epithelial cell proliferation|stimulation of mammary gland epithelial cell proliferation|upregulation of mammary gland epithelial cell proliferation|up-regulation of mammary gland epithelial cell proliferation|activation of mammary gland epithelial cell proliferation													biological_process											owl:Class	
GO:0045259	biolink:NamedThing	proton-transporting ATP synthase complex	A proton-transporting two-sector ATPase complex that catalyzes the phosphorylation of ADP to ATP during oxidative phosphorylation. The complex comprises a membrane sector (F0) that carries out proton transport and a cytoplasmic compartment sector (F1) that catalyzes ATP synthesis by a rotational mechanism; the extramembrane sector (containing 3 a and 3 b subunits) is connected via the d-subunit to the membrane sector by several smaller subunits. Within this complex, the g and e subunits and the 9-12 c subunits rotate by consecutive 120 degree angles and perform parts of ATP synthesis. This movement is driven by the hydrogen ion electrochemical potential gradient.	tmpzr1t_l9r_go_relaxed.owl	hydrogen-translocating F-type ATPase complex|proton-transporting F-type ATPase complex|F1-F0 complex|hydrogen-transporting ATP synthase complex											GO:0045255		cellular_component											owl:Class	
GO:0060592	biolink:NamedThing	mammary gland formation	The process pertaining to the initial formation of the mammary gland from unspecified parts. The process begins with formation of the mammary line and ends when the solid mammary bud invades the primary mammary mesenchyme.	tmpzr1t_l9r_go_relaxed.owl	mammary placode formation|mammary line formation|mammary bud formation|mammary sprout formation							dph	2009-05-13T08:47:52Z					biological_process											owl:Class	
GO:0035196	biolink:NamedThing	production of miRNAs involved in gene silencing by miRNA	Cleavage of stem-loop RNA precursors into microRNAs (miRNAs), a class of small RNAs that primarily silence genes by blocking the translation of mRNA transcripts into protein, or by increasing the degradation of non-protein-coding RNA transcripts.	tmpzr1t_l9r_go_relaxed.owl	microRNA-mediated gene silencing, production of microRNAs|miRNA processing|microRNA metabolic process|production of microRNAs involved in gene silencing by microRNA|microRNA biogenesis|microRNA processing|miRNA biogenesis|microRNA metabolism|miRNA biosynthetic process|microRNA biosynthesis|microRNA biosynthetic process|miRNA-mediated gene silencing, production of miRNAs|gene silencing by miRNA, production of miRNAs											GO:0030918		biological_process											owl:Class	
GO:0002000	biolink:NamedThing	detection of renal blood flow	The process in which the juxtaglomerular cells of the kidneys receive information about the amount of blood flowing through the arterioles and converts the information to a molecular signal.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0035935	biolink:NamedThing	androgen secretion	The regulated release of an androgen into the circulatory system. Androgens are steroid hormones that stimulate or control the development and maintenance of masculine characteristics in vertebrates.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-07-20T01:11:31Z					biological_process											owl:Class	
GO:0033567	biolink:NamedThing	DNA replication, Okazaki fragment processing	The DNA metabolic process, occurring during lagging strand synthesis, by which RNA primers are removed from Okazaki fragments, the resulting gaps filled by DNA polymerization, and the ends ligated to form a continuous strand.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1990794	biolink:NamedThing	basolateral part of cell	The region of a cell situated by the cell sides which interface adjacent cells and near the base. Often used in reference to animal polarized epithelial cells.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-07-09T20:31:50Z					cellular_component											owl:Class	
GO:0001973	biolink:NamedThing	G protein-coupled adenosine receptor signaling pathway	The series of molecular signals generated as a consequence of a receptor binding to extracellular adenosine and transmitting the signal to a heterotrimeric G-protein complex to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	adenosine receptor signaling pathway|adenosine receptor signaling pathway, G-protein coupled|adenosine receptor signalling pathway|P1 receptor signaling pathway													biological_process											owl:Class	
GO:0051229	biolink:NamedThing	meiotic spindle disassembly	The controlled breakdown of the spindle during a meiotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl	meiotic spindle breakdown|spindle breakdown during meiosis|meiotic spindle catabolism|spindle degradation during meiosis|spindle disassembly during meiosis|meiotic spindle degradation													biological_process											owl:Class	
GO:0098843	biolink:NamedThing	postsynaptic endocytic zone	A stably positioned site of clathrin adjacent and physically attached to the postsynaptic specialization, which is the site of endocytosis of post-synaptic proteins.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0014044	biolink:NamedThing	Schwann cell development	The process aimed at the progression of a Schwann cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. Schwann cells are found in the peripheral nervous system, where they insulate neurons and axons, and regulate the environment in which neurons function.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0048908	biolink:NamedThing	anterior lateral line ganglion neuron differentiation	The process in which a relatively unspecialized cell acquires specialized features of a neuron of the anterior lateral line ganglion.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0048907	biolink:NamedThing	anterior lateral line ganglion development	The process whose specific outcome is the progression of the anterior lateral line ganglion over time, from its formation to the mature structure. The anterior lateral line ganglion develops from cranial ectodermal placodes situated between the eye and ear.	tmpzr1t_l9r_go_relaxed.owl	gALL development													biological_process											owl:Class	
GO:0048347	biolink:NamedThing	negative regulation of paraxial mesodermal cell fate determination	Any process that stops, prevents, or reduces the frequency, rate or extent of paraxial mesoderm cell fate determination.	tmpzr1t_l9r_go_relaxed.owl	down regulation of paraxial mesodermal cell fate determination|inhibition of paraxial mesodermal cell fate determination|downregulation of paraxial mesodermal cell fate determination|down-regulation of paraxial mesodermal cell fate determination													biological_process											owl:Class	
GO:0000319	biolink:NamedThing	sulfite transmembrane transporter activity	Enables the transfer of sulfite ions from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	sulphite transporter activity													molecular_function											owl:Class	
GO:0071944	biolink:NamedThing	cell periphery	The part of a cell encompassing the cell cortex, the plasma membrane, and any external encapsulating structures.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-10-04T01:51:47Z					cellular_component											owl:Class	
GO:0072138	biolink:NamedThing	mesenchymal cell proliferation involved in ureteric bud development	The multiplication or reproduction of cells, resulting in the expansion of a mesenchymal cell population of the ureteric bud, that contributes to ureteric bud development.	tmpzr1t_l9r_go_relaxed.owl	ureteric bud mesenchymal cell proliferation							mah	2010-02-22T02:40:38Z					biological_process											owl:Class	
GO:0001657	biolink:NamedThing	ureteric bud development	The process whose specific outcome is the progression of the ureteric bud over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1903346	biolink:NamedThing	positive regulation of protein polyglycylation	Any process that activates or increases the frequency, rate or extent of protein polyglycylation.	tmpzr1t_l9r_go_relaxed.owl	up regulation of protein polyglycylation|up-regulation of protein polyglycylation|upregulation of protein polyglycylation|activation of protein polyglycylation							sart	2014-08-19T09:32:24Z					biological_process											owl:Class	
GO:0140114	biolink:NamedThing	cellular detoxification of fluoride	Any process carried out at the cellular level that reduces or removes the toxicity of a fluoride. These may include transport of fluoride away from sensitive areas and to compartments or complexes whose purpose is sequestration of the toxic substance.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/14391						pg	2017-10-23T15:39:43Z					biological_process											owl:Class	
GO:0004517	biolink:NamedThing	nitric-oxide synthase activity	Catalysis of the reaction: L-arginine + n NADPH + n H+ + m O2 = citrulline + nitric oxide + n NADP+.	tmpzr1t_l9r_go_relaxed.owl	nitric oxide synthase activity|nitric-oxide synthetase activity|L-arginine,NADPH:oxygen oxidoreductase (nitric-oxide-forming) activity|nitric oxide synthetase activity|endothelium-derived relaxation factor-forming enzyme activity|endothelium-derived relaxing factor synthase activity|NO synthase activity|NADPH-diaphorase activity				Reactome:R-HSA-202127|MetaCyc:NITRIC-OXIDE-SYNTHASE-RXN|RHEA:19897|EC:1.14.13.39|Reactome:R-HSA-418436									molecular_function											owl:Class	
GO:0015566	biolink:NamedThing	acriflavine transmembrane transporter activity	Enables the directed movement of acriflavin from one side of a membrane to the other. Acriflavin is a fluorescent dye used as a local antiseptic and also as a biological stain. It intercalates into nucleic acids thereby inhibiting bacterial and viral replication.	tmpzr1t_l9r_go_relaxed.owl	acriflavine transporter activity|acriflavin resistant pump activity|acriflavin transporter activity											GO:0015555		molecular_function											owl:Class	
GO:0015894	biolink:NamedThing	acriflavine transport	The directed movement of acriflavine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Acriflavine is a fluorescent dye used as a local antiseptic and also as a biological stain. It intercalates into nucleic acids thereby inhibiting bacterial and viral replication.	tmpzr1t_l9r_go_relaxed.owl	acriflavin transport													biological_process											owl:Class	
GO:0140651	biolink:NamedThing	futile creatine cycle	The phosphorylation and dephosphorylation of creatine in a futile cycle, which dissipates the high energy charge of phosphocreatine as heat without performing any mechanical or chemical work. The futile creatine cycle takes place in thermogenic fat cells and is part of adaptive thermogenesis.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/21517						pg	2021-05-26T06:40:18Z					biological_process											owl:Class	
GO:0050187	biolink:NamedThing	phosphoamidase activity	Catalysis of the reaction: N-phosphocreatine + H(2)O = creatine + phosphate.	tmpzr1t_l9r_go_relaxed.owl	phosphamide hydrolase activity|creatine phosphatase activity				MetaCyc:PHOSPHOAMIDASE-RXN|EC:3.9.1.1|RHEA:12977|KEGG_REACTION:R01882									molecular_function											owl:Class	
GO:0006957	biolink:NamedThing	complement activation, alternative pathway	Any process involved in the activation of any of the steps of the alternative pathway of the complement cascade which allows for the direct killing of microbes and the regulation of other immune processes.	tmpzr1t_l9r_go_relaxed.owl	complement cascade, alternative pathway													biological_process											owl:Class	
GO:0060386	biolink:NamedThing	synapse assembly involved in innervation	The assembly of a synapse within a target tissue in which a nerve is invading.	tmpzr1t_l9r_go_relaxed.owl	synaptogenesis involved in innervation|synapse biogenesis involved in innervation													biological_process											owl:Class	
GO:0043061	biolink:NamedThing	meiotic metaphase II plate congression	The alignment of chromosomes at the metaphase plate, a plane halfway between the poles of the meiotic spindle, during meiosis II.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0060225	biolink:NamedThing	positive regulation of retinal rod cell fate commitment	Any process that increases the process in which the developmental fate of a cell becomes restricted such that it will develop into a retinal rod cell. A retinal rod cell is one of the two photoreceptor subtypes in a camera-type eye.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1901582	biolink:NamedThing	positive regulation of telomeric RNA transcription from RNA pol II promoter	Any process that activates or increases the frequency, rate or extent of telomeric RNA transcription from RNA pol II promoter.	tmpzr1t_l9r_go_relaxed.owl	up regulation of telomeric RNA transcription from Pol II promoter|activation of telomeric RNA transcription from RNA pol II promoter|up regulation of telomeric RNA transcription from RNA pol II promoter|activation of telomeric RNA transcription from Pol II promoter|upregulation of telomeric RNA transcription from RNA pol II promoter|positive regulation of telomeric RNA transcription from Pol II promoter|up-regulation of telomeric RNA transcription from Pol II promoter|up-regulation of telomeric RNA transcription from RNA pol II promoter|upregulation of telomeric RNA transcription from Pol II promoter							al	2012-11-06T11:07:25Z					biological_process											owl:Class	
GO:0061608	biolink:NamedThing	nuclear import signal receptor activity	Combining with a nuclear import signal (NIS) on a cargo to be transported, to mediate transport of the cargo through the nuclear pore, from the cytoplasm to the nuclear lumen. The cargo can be either a RNA or a protein.	tmpzr1t_l9r_go_relaxed.owl	importin activity	https://github.com/geneontology/go-ontology/issues/14336						dph	2014-03-03T07:58:18Z					molecular_function											owl:Class	
GO:0072023	biolink:NamedThing	thick ascending limb development	The process whose specific outcome is the progression of the thick ascending limb over time, from its formation to the mature structure. The thick ascending limb is the last part of the loop of Henle. Its thick, mitochondria-rich epithelium characterizes the outer medulla, and is responsible for very avid active salt transport. At the macula densa, the thick ascending limb connects to the distal convoluted tubule.	tmpzr1t_l9r_go_relaxed.owl	TAL development							mah	2010-01-25T02:39:51Z			GO:0072026		biological_process											owl:Class	
GO:0099580	biolink:NamedThing	ion antiporter activity involved in regulation of postsynaptic membrane potential	Any ion antiporter activity, occurring in the postsynaptic membrane, that is involved in regulation of postsynaptic membrane potential.	tmpzr1t_l9r_go_relaxed.owl	ion antiporter activity involved in regulation of post-synaptic membrane potential													molecular_function											owl:Class	
GO:1901541	biolink:NamedThing	ent-pimara-8(14),15-diene biosynthetic process	The chemical reactions and pathways resulting in the formation of ent-pimara-8(14),15-diene.	tmpzr1t_l9r_go_relaxed.owl	ent-pimara-8(14),15-diene synthesis|ent-pimara-8(14),15-diene formation|ent-pimara-8(14),15-diene anabolism|ent-pimara-8(14),15-diene biosynthesis							di	2012-10-25T15:38:21Z					biological_process											owl:Class	
GO:0103116	biolink:NamedThing	ABC-type D-galactofuranose transporter	Catalysis of the reaction: alpha-D-galactofuranose + ATP + H2O <=> alpha-D-galactofuranose + hydrogenphosphate + ADP + H+.	tmpzr1t_l9r_go_relaxed.owl	ATP-dependent alpha-D-galactofuranose transporter activity|alpha-D-galactofuranose transporter activity|ATPase-coupled alpha-D-galactofuranose transporter activity				RHEA:61716|EC:7.5.2.9|MetaCyc:TRANS-RXN0-491									molecular_function											owl:Class	
GO:0060591	biolink:NamedThing	chondroblast differentiation	The process in which a mesenchymal cell, acquires specialized structural and/or functional features of a chondroblast. Differentiation includes the processes involved in commitment of a cell to a chondroblast fate. A chondroblast is a precursor cell to chondrocytes.	tmpzr1t_l9r_go_relaxed.owl	chondrocyte progenitor cell differentiation							dph	2009-05-11T07:47:36Z					biological_process											owl:Class	
GO:0090112	biolink:NamedThing	COPII vesicle uncoating	The process in which COPII vesicle coat proteins are disassembled, and released.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-12-06T08:56:50Z					biological_process											owl:Class	
GO:1902680	biolink:NamedThing	positive regulation of RNA biosynthetic process	Any process that activates or increases the frequency, rate or extent of RNA biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	upregulation of RNA biosynthetic process|upregulation of RNA biosynthesis|up-regulation of RNA biosynthetic process|activation of RNA anabolism|up regulation of RNA anabolism|upregulation of RNA anabolism|positive regulation of RNA anabolism|activation of RNA biosynthetic process|activation of RNA synthesis|up regulation of RNA biosynthesis|upregulation of RNA synthesis|up regulation of RNA formation|activation of RNA formation|up-regulation of RNA synthesis|up regulation of RNA biosynthetic process|up-regulation of RNA formation|up-regulation of RNA biosynthesis|up regulation of RNA synthesis|positive regulation of RNA biosynthesis|positive regulation of RNA synthesis|activation of RNA biosynthesis|up-regulation of RNA anabolism|upregulation of RNA formation|positive regulation of RNA formation							jl	2014-02-05T16:32:10Z					biological_process											owl:Class	
GO:0072656	biolink:NamedThing	maintenance of protein location in mitochondrion	Any process in which a protein is maintained in a specific location in a mitochondrion, and is prevented from moving elsewhere.	tmpzr1t_l9r_go_relaxed.owl								mah	2011-02-14T02:30:43Z					biological_process											owl:Class	
GO:0120308	biolink:NamedThing	axonemal outer doublet assembly	The aggregation, arrangement and bonding together of a set of components to form an axonemal outer doublet, a part of an axoneme consisting of a doublet microtubule.	tmpzr1t_l9r_go_relaxed.owl	axoneme outer doublet assembly|axonemal outer doublet morphogenesis|outer-doublet microtubule assembly|axonemal outer doublet biogenesis|outer doublet assembly|axonemal outer doublet formation	https://github.com/geneontology/go-ontology/issues/21154						krc	2021-03-23T16:28:18Z					biological_process											owl:Class	
GO:0060515	biolink:NamedThing	prostate field specification	The process that results in the delineation of a specific region of the urogenital sinus epithelium into the area in which the prostate gland will develop.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0071659	biolink:NamedThing	negative regulation of IP-10 production	Any process that stops, prevents, or reduces the frequency, rate, or extent of production of IP-10.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of chemokine (C-C motif) ligand 10 production|negative regulation of CXCL10 production							mah	2010-02-12T10:41:14Z					biological_process											owl:Class	
GO:0035773	biolink:NamedThing	insulin secretion involved in cellular response to glucose stimulus	The regulated release of proinsulin from secretory granules (B granules) in the B cells of the pancreas; accompanied by cleavage of proinsulin to form mature insulin, in response to a glucose stimulus.	tmpzr1t_l9r_go_relaxed.owl	insulin secretion involved in cellular response to glucose							bf	2011-04-01T01:14:40Z					biological_process											owl:Class	
GO:2000728	biolink:NamedThing	regulation of mRNA export from nucleus in response to heat stress	Any process that modulates the frequency, rate or extent of mRNA export from nucleus in response to heat stress.	tmpzr1t_l9r_go_relaxed.owl	regulation of mRNA export from nucleus during heat stress|regulation of mRNA export from cell nucleus during heat stress							pr	2011-06-08T12:17:45Z					biological_process											owl:Class	
GO:0031990	biolink:NamedThing	mRNA export from nucleus in response to heat stress	The directed movement of mRNA from the nucleus to the cytoplasm during a heat stimulus, a temperature stimulus above the optimal temperature for the organism; in particular, a process that enables an organism withstand exposure to temperatures that would otherwise lethally impair poly(A)+ mRNA-nucleus export.	tmpzr1t_l9r_go_relaxed.owl	mRNA export from nucleus during heat stress|mRNA export from cell nucleus during heat stress													biological_process											owl:Class	
GO:0016318	biolink:NamedThing	ommatidial rotation	The process in which photoreceptors are arranged in ommatidia in the dorsal and ventral fields to be mirror images. The polarity is established in the imaginal discs concurrently with cell fate specification.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0042067	biolink:NamedThing	establishment of ommatidial planar polarity	The specification of polarized ommatidia. Ommatidia occur in two chiral forms. The trapezoidal arrangement of photoreceptors in the dorsal part of the eye is the mirror image of that in the ventral part.	tmpzr1t_l9r_go_relaxed.owl	establishment of ommatidial polarity													biological_process											owl:Class	
GO:0071701	biolink:NamedThing	regulation of MAPK export from nucleus	Any process that modulates the frequency, rate or extent of the directed movement of a MAP kinase from the nucleus to the cytoplasm.	tmpzr1t_l9r_go_relaxed.owl	regulation of cytoplasmic translocation of MAP kinase|regulation of MAPK export from cell nucleus|regulation of MAPK-nucleus export|regulation of cytoplasmic translocation of mitogen-activated protein kinase|regulation of MAPK export out of nucleus|regulation of MAPK transport from nucleus to cytoplasm							mah	2010-03-02T01:24:12Z					biological_process											owl:Class	
GO:0045204	biolink:NamedThing	MAPK export from nucleus	The directed movement of a MAP kinase from the nucleus to the cytoplasm.	tmpzr1t_l9r_go_relaxed.owl	cytoplasmic translocation of MAP kinase|MAPK-nucleus export|cytoplasmic translocation of mitogen-activated protein kinase|MAPK transport from nucleus to cytoplasm|MAPK export out of nucleus|MAPK export from cell nucleus													biological_process											owl:Class	
GO:1901482	biolink:NamedThing	L-lysine import into vacuole involved in cellular response to nitrogen starvation	A L-lysine import into the vacuole that is involved in cellular response to nitrogen starvation.	tmpzr1t_l9r_go_relaxed.owl								al	2012-10-08T08:34:03Z					biological_process											owl:Class	
GO:0030671	biolink:NamedThing	clathrin-coated phagocytic vesicle membrane	The lipid bilayer surrounding a clathrin-coated phagocytic vesicle.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:1902947	biolink:NamedThing	regulation of tau-protein kinase activity	Any process that modulates the frequency, rate or extent of tau-protein kinase activity.	tmpzr1t_l9r_go_relaxed.owl	regulation of ATP:tau-protein O-phosphotransferase activity|regulation of STK31|regulation of tau-protein kinase II activity|regulation of tau kinase activity|regulation of TPK I|regulation of protein tau kinase activity|regulation of tau-tubulin kinase activity|regulation of [Tau protein] kinase activity|regulation of TTK|regulation of tau protein kinase activity|regulation of TPK|regulation of cdk5/p20|regulation of glycogen synthase kinase-3beta activity|regulation of TPK II|regulation of tau-protein kinase I activity|regulation of brain protein kinase PK40erk activity|regulation of GSK|regulation of CDK5/p23							sjp	2014-05-02T08:43:27Z					biological_process											owl:Class	
GO:0034496	biolink:NamedThing	multivesicular body membrane disassembly	The controlled breakdown of the membranes of multivesicular bodies.	tmpzr1t_l9r_go_relaxed.owl	MVB membrane disassembly													biological_process											owl:Class	
GO:0039022	biolink:NamedThing	pronephric duct development	The process whose specific outcome is the progression of the pronephric duct over time, from its formation to the mature structure. The pronephric duct collects the filtrate from the pronephric tubules and opens to the exterior of the pronephric kidney.	tmpzr1t_l9r_go_relaxed.owl								bf	2010-07-02T10:15:03Z					biological_process											owl:Class	
GO:1902595	biolink:NamedThing	regulation of DNA replication origin binding	Any process that modulates the frequency, rate or extent of DNA replication origin binding.	tmpzr1t_l9r_go_relaxed.owl	regulation of ARS binding							mah	2013-12-19T16:19:39Z					biological_process											owl:Class	
GO:0003688	biolink:NamedThing	DNA replication origin binding	Binding to a DNA replication origin, a unique DNA sequence of a replicon at which DNA replication is initiated and proceeds bidirectionally or unidirectionally.	tmpzr1t_l9r_go_relaxed.owl	ARS binding													molecular_function											owl:Class	
GO:0014010	biolink:NamedThing	Schwann cell proliferation	The multiplication or reproduction of Schwann cells, resulting in the expansion of their population. Schwann cells are a type of glial cell in the peripheral nervous system.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0009782	biolink:NamedThing	photosystem I antenna complex	The antenna complex of photosystem I. A photosystem has two closely linked components, an antenna containing light-absorbing pigments and a reaction center. Each antenna contains one or more light-harvesting complexes (LHCs).	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0061309	biolink:NamedThing	cardiac neural crest cell development involved in outflow tract morphogenesis	The process aimed at the progression of a cardiac neural crest cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell that contributes to the shaping of the outflow tract.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-09-23T09:08:37Z					biological_process											owl:Class	
GO:0060037	biolink:NamedThing	pharyngeal system development	The process whose specific outcome is the progression of the pharyngeal system over time, from its formation to the mature structure. The pharyngeal system is a transient embryonic complex that is specific to vertebrates. It comprises the pharyngeal arches, bulges of tissues of mesoderm and neural crest derivation through which pass nerves and pharyngeal arch arteries. The arches are separated internally by pharyngeal pouches, evaginations of foregut endoderm, and externally by pharyngeal clefts, invaginations of surface ectoderm. The development of the system ends when the stucture it contributes to are forming: the thymus, thyroid, parathyroids, maxilla, mandible, aortic arch, cardiac outflow tract, external and middle ear.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0022005	biolink:NamedThing	midbrain-hindbrain boundary maturation during neural plate development	A developmental process occurring before the brain has been specified along the neural axis that is required for the midbrain-hindbrain boundary to attain its fully functional state. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate.	tmpzr1t_l9r_go_relaxed.owl	midbrain-hindbrain boundary maturation involved in neural plate development													biological_process											owl:Class	
GO:0022011	biolink:NamedThing	myelination in peripheral nervous system	The process in which neuronal axons and dendrites become coated with a segmented lipid-rich sheath (myelin) to enable faster and more energetically efficient conduction of electrical impulses. The sheath is formed by the cell membranes of Schwann cells in the peripheral nervous system. Adjacent myelin segments are separated by a non-myelinated stretch of axon called a node of Ranvier.	tmpzr1t_l9r_go_relaxed.owl	peripheral nervous system myelination													biological_process											owl:Class	
GO:0120041	biolink:NamedThing	positive regulation of macrophage proliferation	Any process that activates or increases the frequency, rate or extent of macrophage proliferation.	tmpzr1t_l9r_go_relaxed.owl								krc	2017-05-10T20:45:01Z					biological_process											owl:Class	
GO:0106098	biolink:NamedThing	NAGS/NAGK complex	A protein complex that acts both as N-acetylglutamate synthase (NAGS) catalysing the production of N-Acetylglutamate from glutamate and acetyl-CoA, and as N-acetylglutamate kinase (NAGK) catalysing the reaction ATP + N-acetyl-L-glutamate = ADP + N-acetyl-L-glutamyl 5-phosphate.	tmpzr1t_l9r_go_relaxed.owl								hjd	2018-02-15T00:22:31Z					cellular_component											owl:Class	
GO:0080091	biolink:NamedThing	regulation of raffinose metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving raffinose.	tmpzr1t_l9r_go_relaxed.owl								dhl	2009-04-22T04:36:27Z					biological_process											owl:Class	
GO:0033530	biolink:NamedThing	raffinose metabolic process	The chemical reactions and pathways involving raffinose, the trisaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside.	tmpzr1t_l9r_go_relaxed.owl	raffinose metabolism													biological_process											owl:Class	
GO:0038181	biolink:NamedThing	bile acid receptor activity	Combining with a bile acid and transmitting the signal to initiate a change in cell activity. A bile acid is any member of a group of steroid carboxylic acids occurring in bile.	tmpzr1t_l9r_go_relaxed.owl								bf	2013-05-16T10:27:02Z					molecular_function											owl:Class	
GO:0080001	biolink:NamedThing	mucilage extrusion from seed coat	The process in which seed mucilage expands through hydration and breaks the outer cell wall that encapsulates the whole seed upon imbibition. Mucilage, mainly composed of pectins, is formed during seed development and deposited into the apoplast underneath the outer wall of the seed coat.	tmpzr1t_l9r_go_relaxed.owl	secretion of mucilage from seed coat|mucilage release from seed coat													biological_process											owl:Class	
GO:0043587	biolink:NamedThing	tongue morphogenesis	The process in which the anatomical structures of the tongue are generated and organized. The tongue is the movable, muscular organ on the floor of the mouth of most vertebrates, in man other mammals is the principal organ of taste, aids in the prehension of food, in swallowing, and in modifying the voice as in speech.	tmpzr1t_l9r_go_relaxed.owl	glossa morphogenesis|lingua morphogenesis													biological_process											owl:Class	
GO:0050051	biolink:NamedThing	leukotriene-B4 20-monooxygenase activity	Catalysis of the reaction: leukotriene B4 + O2 + reduced [NADPH-hemoprotein reductase] = 20-hydroxy-leukotriene B4 + H+ + H2O + oxidized [NADPH-hemoprotein reductase].	tmpzr1t_l9r_go_relaxed.owl	LTB4 20-hydroxylase activity|LTB4 omega-hydroxylase activity|leukotriene-B4 omega-hydroxylase activity|leukotriene-B4 20-hydroxylase activity|LTB(4) 20-hydroxylase activity|LTB(4) omega-hydroxylase activity				EC:1.14.14.94|RHEA:22176|MetaCyc:LEUKOTRIENE-B4-20-MONOOXYGENASE-RXN|Reactome:R-HSA-211873									molecular_function											owl:Class	
GO:0048315	biolink:NamedThing	conidium formation	The process of producing non-motile spores, called conidia, via mitotic asexual reproduction in higher fungi. Conidia are haploid cells genetically identical to their haploid parent. They are produced by conversion of hyphal elements, or are borne on sporogenous cells on or within specialized structures termed conidiophores, and participate in dispersal of the fungus.	tmpzr1t_l9r_go_relaxed.owl	conidia formation|conidia biosynthesis													biological_process											owl:Class	
GO:0140610	biolink:NamedThing	RNA sequestering activity	The selective interaction of a protein with a specific RNA molecule to prevent it from interacting with other partners or inhibiting its localization to other areas of the cell.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/20945						pg	2021-02-24T13:53:46Z					molecular_function											owl:Class	
GO:1990583	biolink:NamedThing	phospholipase D activator activity	Increases the activity of the enzyme phospholipase D.	tmpzr1t_l9r_go_relaxed.owl								sl	2014-12-10T21:04:46Z					molecular_function											owl:Class	
GO:0071807	biolink:NamedThing	replication fork arrest involved in DNA replication termination	A replication fork arrest process that contributes to the termination of DNA replication.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-09-03T03:26:38Z					biological_process											owl:Class	
GO:0048376	biolink:NamedThing	positive regulation of lateral mesodermal cell fate determination	Any process that activates or increases the frequency, rate or extent of lateral mesoderm cell fate determination.	tmpzr1t_l9r_go_relaxed.owl	stimulation of lateral mesodermal cell fate determination|upregulation of lateral mesodermal cell fate determination|up regulation of lateral mesodermal cell fate determination|up-regulation of lateral mesodermal cell fate determination|activation of lateral mesodermal cell fate determination|positive regulation of lateral plate mesodermal cell fate determination													biological_process											owl:Class	
GO:0048373	biolink:NamedThing	lateral mesodermal cell fate determination	The process in which a cell becomes capable of differentiating autonomously into a lateral mesoderm cell regardless of its environment; upon determination, the cell fate cannot be reversed.	tmpzr1t_l9r_go_relaxed.owl	lateral plate mesodermal cell fate determination|lateral mesoderm cell fate determination|lateral plate mesoderm cell fate determination													biological_process											owl:Class	
GO:1990836	biolink:NamedThing	lysosomal matrix	A matrix composed of supramolecular assemblies of lysosomal enzymes and lipids which forms at a pH of 5.0 within the lysosome.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-08-25T17:04:12Z					cellular_component											owl:Class	
GO:1900635	biolink:NamedThing	heptadecane metabolic process	The chemical reactions and pathways involving heptadecane.	tmpzr1t_l9r_go_relaxed.owl	heptadecane metabolism							tt	2012-05-21T07:05:01Z					biological_process											owl:Class	
GO:0031450	biolink:NamedThing	negative regulation of slow-twitch skeletal muscle fiber contraction	Any process that stops, prevents, or reduces the frequency, rate or extent of slow-twitch skeletal muscle contraction.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of slow-twitch skeletal muscle contraction|inhibition of slow-twitch skeletal muscle contraction|down regulation of slow-twitch skeletal muscle contraction|downregulation of slow-twitch skeletal muscle contraction|down-regulation of slow-twitch skeletal muscle contraction													biological_process											owl:Class	
GO:0031444	biolink:NamedThing	slow-twitch skeletal muscle fiber contraction	A process in which force is generated within slow-twitch skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The slow-twitch skeletal muscle is characterized by slow time parameters, low force development and resistance to fatigue.	tmpzr1t_l9r_go_relaxed.owl	slow-twitch skeletal muscle fibre contraction													biological_process											owl:Class	
GO:0075242	biolink:NamedThing	negative regulation of zoospore formation	Any process that stops, prevents, or reduces the frequency, rate or extent of zoospore formation, a process in which a diploid cell undergoes meiosis, and the meiotic products acquire specialized features of asexual motile mononucleate flagellated spores called zoospores.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0008258	biolink:NamedThing	head involution	Movement of the anterior ectoderm to the interior of the embryo.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1902463	biolink:NamedThing	protein localization to cell leading edge	A process in which a protein is transported to, or maintained in, a location within a cell leading edge.	tmpzr1t_l9r_go_relaxed.owl	protein localisation to cell leading edge|protein localisation in cell leading edge|protein localization in cell leading edge							jl	2013-10-22T12:36:07Z					biological_process											owl:Class	
GO:0002280	biolink:NamedThing	monocyte activation involved in immune response	The change in morphology and behavior of a monocyte resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response.	tmpzr1t_l9r_go_relaxed.owl	monocyte activation during immune response													biological_process											owl:Class	
GO:0031656	biolink:NamedThing	positive regulation of heat dissipation	Any process that activates or increases the rate or extent of heat dissipation.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of heat dissipation|upregulation of heat dissipation|up regulation of heat dissipation|activation of heat dissipation|stimulation of heat dissipation													biological_process											owl:Class	
GO:0006258	biolink:NamedThing	UDP-glucose catabolic process	The chemical reactions and pathways resulting in the breakdown of UDP-glucose, uridinediphosphoglucose, a substance composed of glucose in glycosidic linkage with uridine diphosphate.	tmpzr1t_l9r_go_relaxed.owl	UDP-glucose breakdown|UDP-glucose conversion|UDP-glucose degradation|UDP-glucose catabolism											GO:0019691		biological_process											owl:Class	
GO:0090333	biolink:NamedThing	regulation of stomatal closure	Any process that modulates the rate, frequency, or extent of stomatal closure. Stomatal closure is the process of closing of stomata, pores in the epidermis of leaves and stems bordered by two guard cells and serving in gas exchange.	tmpzr1t_l9r_go_relaxed.owl								tb	2010-05-26T02:14:49Z					biological_process											owl:Class	
GO:0090332	biolink:NamedThing	stomatal closure	The process of closing of stomata, pores in the epidermis of leaves and stems bordered by two guard cells and serving in gas exchange.	tmpzr1t_l9r_go_relaxed.owl								tb	2010-05-26T02:14:49Z					biological_process											owl:Class	
GO:0045186	biolink:NamedThing	zonula adherens assembly	Assembly of the zonula adherens, a cell-cell adherens junction which forms a continuous belt near the apex of epithelial cells.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0017133	biolink:NamedThing	mitochondrial electron transfer flavoprotein complex	A protein complex located in the mitochondrion. It contains flavin adenine dinucleotide (FAD) that, together with an acyl-CoA dehydrogenase, forms a system that oxidizes an acyl-CoA molecule and reduces ubiquinone and other acceptors in the mitochondrial electron transport system.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0061598	biolink:NamedThing	molybdopterin adenylyltransferase activity	Catalysis of the reaction ATP + molybdopterin = diphosphate + adenylyl-molybdopterin.	tmpzr1t_l9r_go_relaxed.owl					RHEA:31331|EC:2.7.7.75			dph	2014-02-10T14:14:06Z					molecular_function											owl:Class	
GO:2000339	biolink:NamedThing	negative regulation of chemokine (C-X-C motif) ligand 1 production	Any process that stops, prevents or reduces the frequency, rate or extent of chemokine (C-X-C motif) ligand 1 production.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of SCYB1 production|negative regulation of CXCL1 production|negative regulation of KC production|negative regulation of keratinocyte derived chemokine production							mah	2011-02-01T10:46:31Z					biological_process											owl:Class	
GO:0072566	biolink:NamedThing	chemokine (C-X-C motif) ligand 1 production	The appearance of chemokine (C-X-C motif) ligand 1 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	tmpzr1t_l9r_go_relaxed.owl	SCYB1 production|CXCL1 production|KC production|keratinocyte derived chemokine production							mah	2011-01-31T11:31:58Z					biological_process											owl:Class	
GO:0006123	biolink:NamedThing	mitochondrial electron transport, cytochrome c to oxygen	The transfer of electrons from cytochrome c to oxygen that occurs during oxidative phosphorylation, mediated by the multisubunit enzyme known as complex IV.	tmpzr1t_l9r_go_relaxed.owl	complex IV (reduction of O2)													biological_process											owl:Class	
GO:0042584	biolink:NamedThing	chromaffin granule membrane	The lipid bilayer surrounding a chromaffin granule, a specialized secretory vesicle found in the cells of adrenal glands and various other organs, which is concerned with the synthesis, storage, metabolism, and secretion of epinephrine and norepinephrine.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:1904286	biolink:NamedThing	negative regulation of protein-pyridoxal-5-phosphate linkage	Any process that stops, prevents or reduces the frequency, rate or extent of protein-pyridoxal-5-phosphate linkage.	tmpzr1t_l9r_go_relaxed.owl	downregulation of protein-pyridoxal-5-phosphate linkage|down-regulation of protein-pyridoxal-5-phosphate linkage|inhibition of protein-pyridoxal-5-phosphate linkage|down regulation of protein-pyridoxal-5-phosphate linkage							mcc	2015-06-05T17:21:21Z					biological_process											owl:Class	
GO:0034044	biolink:NamedThing	exomer complex	A protein complex that forms a coat structure on vesicles involved in exocytosis of proteins from the trans-Golgi network to the cell surface; in Saccharomyces, the complex contains Chs5p, Chs6p, and Chs6p paralogues.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0010256	biolink:NamedThing	endomembrane system organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endomembrane system.	tmpzr1t_l9r_go_relaxed.owl	endomembrane organization|endomembrane system organisation													biological_process											owl:Class	
GO:0042012	biolink:NamedThing	interleukin-16 receptor activity	Combining with interleukin-16 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	IL-16 receptor activity|IL-16R													molecular_function											owl:Class	
GO:0042011	biolink:NamedThing	interleukin-16 binding	Binding to interleukin-16.	tmpzr1t_l9r_go_relaxed.owl	IL-16 binding													molecular_function											owl:Class	
GO:0016182	biolink:NamedThing	synaptic vesicle budding from endosome	Budding of synaptic vesicles during the formation of constitutive recycling vesicles from early endosomes.	tmpzr1t_l9r_go_relaxed.owl	endosome to synaptic vesicle budding|synaptic vesicle budding involved in synaptic vesicle exocytosis													biological_process											owl:Class	
GO:0046812	biolink:NamedThing	host cell surface binding	Binding to the surface of a host cell.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0060775	biolink:NamedThing	planar cell polarity pathway involved in gastrula mediolateral intercalation	The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors including C-Jun N-terminal kinase (JNK) contributing to the interdigitation of cells along the mediolateral axis during gastrulation.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-07-25T06:52:50Z					biological_process											owl:Class	
GO:0060031	biolink:NamedThing	mediolateral intercalation	The interdigitation of cells along the mediolateral axis during gastrulation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0075195	biolink:NamedThing	negative regulation of haustorium mother cell formation	Any process that stops, prevents, or reduces the frequency, rate or extent of symbiont haustorium mother cell formation. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of haustorium mother cell formation on or near host					Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products from the symbiont involved in this process.								biological_process											owl:Class	
GO:0002505	biolink:NamedThing	antigen processing and presentation of polysaccharide antigen via MHC class II	The process in which an antigen-presenting cell expresses a polysaccharide antigen on its cell surface in association with an MHC class II protein complex.	tmpzr1t_l9r_go_relaxed.owl	polysaccharide antigen processing and presentation via MHC class II													biological_process											owl:Class	
GO:0046861	biolink:NamedThing	glyoxysomal membrane	The lipid bilayer surrounding a glyoxysome.	tmpzr1t_l9r_go_relaxed.owl	glyoxysome membrane													cellular_component											owl:Class	
GO:0009514	biolink:NamedThing	glyoxysome	A specialized form of peroxisome that contains the enzymes of the glyoxylate pathway. The glyoxysome is found in some plant cells, notably the cells of germinating seeds.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Glyoxysome									cellular_component											owl:Class	
GO:0048242	biolink:NamedThing	epinephrine secretion	The regulated release of epinephrine by a cell. Epinephrine is a catecholamine hormone secreted by the adrenal medulla and a neurotransmitter, released by certain neurons and active in the central nervous system.	tmpzr1t_l9r_go_relaxed.owl	adrenaline secretion													biological_process											owl:Class	
GO:0033759	biolink:NamedThing	flavone synthase activity	Catalysis of the reaction: a flavanone + 2-oxoglutarate + O2 = a flavone + succinate + CO2 + H2O.	tmpzr1t_l9r_go_relaxed.owl	flavone synthase I activity|flavanone,2-oxoglutarate:oxygen oxidoreductase (dehydrating) activity|FNS I				RHEA:10448|MetaCyc:RXN-8000|EC:1.14.20.5									molecular_function											owl:Class	
GO:0090674	biolink:NamedThing	endothelial cell-matrix adhesion via fibronectin	The binding of an endothelial cell to the extracellular matrix via fibronectin.	tmpzr1t_l9r_go_relaxed.owl								tb	2016-01-15T15:40:58Z					biological_process											owl:Class	
GO:0005726	biolink:NamedThing	perichromatin fibrils	Structures of variable diameter visible in the nucleoplasm by electron microscopy, mainly observed near the border of condensed chromatin. The fibrils are enriched in RNA, and are believed to be sites of pre-mRNA splicing and polyadenylylation representing the in situ form of nascent transcripts.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0070544	biolink:NamedThing	histone H3-K36 demethylation	The modification of histone H3 by the removal of a methyl group from lysine at position 36 of the histone.	tmpzr1t_l9r_go_relaxed.owl	H3K36 demethylation													biological_process											owl:Class	
GO:0032621	biolink:NamedThing	interleukin-18 production	The appearance of interleukin-18 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	tmpzr1t_l9r_go_relaxed.owl	IL1F4 production|interleukin-18 secretion|IL-18 production|interleukin-18 biosynthetic process|IGIF production											GO:0072616|GO:0042241		biological_process											owl:Class	
GO:0021996	biolink:NamedThing	lamina terminalis formation	The process in which the anterior-most portion of the neural axis is formed by closure of the anterior neuropore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0021506	biolink:NamedThing	anterior neuropore closure	The joining together of the neural folds of the rostral opening of the neural tube. The anterior neuropore appears before the process of neural tube closure is complete.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0080020	biolink:NamedThing	regulation of coenzyme A biosynthetic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving coenzyme A.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0007277	biolink:NamedThing	pole cell development	The process whose specific outcome is the progression of the pole cell over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0001740	biolink:NamedThing	Barr body	A structure found in a female mammalian cell containing an unpaired X chromosome that has become densely heterochromatic, silenced and localized at the nuclear periphery.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Barr_body|NIF_Subcellular:sao1571698684									cellular_component											owl:Class	
GO:0030994	biolink:NamedThing	primary cell septum disassembly	Dissolution of the primary septum during cell separation.	tmpzr1t_l9r_go_relaxed.owl	hydrolysis of primary cell septum|primary septum hydrolysis|primary cell septum hydrolysis													biological_process											owl:Class	
GO:0000920	biolink:NamedThing	septum digestion after cytokinesis	The process of physically separating the septal cell wall material by enzymatic digestion, that occurs after daughter cells are separated by cytokinesis.	tmpzr1t_l9r_go_relaxed.owl	mitotic cytokinetic cell separation|cell separation after cytokinesis|cytokinetic cell separation|daughter cell separation|cell separation following cytokinesis					This term should not be used to describe the last step of cytokinesis in organisms without a cell wall, ie, the cell resealing of the plasma membrane via abscission. Consider annotating to 'GO:0061952 midbody abscission' to capture this process.						GO:1902409|GO:2000695		biological_process											owl:Class	
GO:0005692	biolink:NamedThing	U11 snRNP	A ribonucleoprotein complex that contains small nuclear RNA U11, a heptameric ring of Sm proteins, as well as several proteins that are unique to the U11 snRNP, most of which remain associated with the U11 snRNA both while the U11 snRNP is free or assembled into a series of spliceosomal complexes.	tmpzr1t_l9r_go_relaxed.owl	12S U11 snRNP|snRNP U11													cellular_component											owl:Class	
GO:0060132	biolink:NamedThing	prolactin secreting cell development	The process whose specific outcome is the progression of a prolactin secreting cell over time, from its formation to the mature structure. A prolactin secreting cell is an acidophilic cell of the anterior pituitary that produces prolactin.	tmpzr1t_l9r_go_relaxed.owl	mammotroph development|lactotropic cell development|lactotroph development|lactotrope development|mammotrophic cell development|mammotrope development|mammotropic cell development|epsilon-acidophil development													biological_process											owl:Class	
GO:0048398	biolink:NamedThing	intermediate mesodermal cell fate specification	The process in which a cell becomes capable of differentiating autonomously into an intermediate mesoderm cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.	tmpzr1t_l9r_go_relaxed.owl	intermediate mesoderm cell fate specification													biological_process											owl:Class	
GO:0072675	biolink:NamedThing	osteoclast fusion	The plasma membrane fusion process that results in fusion of mononuclear osteoclasts to form a multinuclear osteoclast.	tmpzr1t_l9r_go_relaxed.owl								mah	2011-02-22T02:14:34Z					biological_process											owl:Class	
GO:0072674	biolink:NamedThing	multinuclear osteoclast differentiation	The process in which a relatively unspecialized monocyte acquires the specialized features of a multinuclear osteoclast. An osteoclast is a specialized phagocytic cell associated with the absorption and removal of the mineralized matrix of bone tissue.	tmpzr1t_l9r_go_relaxed.owl	multinuclear osteoclast morphogenesis|multinuclear osteoclast formation							mah	2011-02-22T02:10:38Z					biological_process											owl:Class	
GO:2000714	biolink:NamedThing	positive regulation of maintenance of meiotic sister chromatid cohesion, arms	Any process that activates or increases the frequency, rate or extent of maintenance of meiotic sister chromatid cohesion along the chromosome arms.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of maintenance of meiotic sister chromatin cohesion along arms|positive regulation of maintenance of sister chromatin cohesion along arms at meiosis I							mah	2011-06-01T12:45:42Z					biological_process											owl:Class	
GO:0048185	biolink:NamedThing	activin binding	Binding to activin, a dimer of inhibin-beta subunits.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0008017	biolink:NamedThing	microtubule binding	Binding to a microtubule, a filament composed of tubulin monomers.	tmpzr1t_l9r_go_relaxed.owl	microtubule/chromatin interaction|microtubule severing activity				Reactome:R-HSA-9614343									molecular_function											owl:Class	
GO:0061407	biolink:NamedThing	positive regulation of transcription from RNA polymerase II promoter in response to hydrogen peroxide	Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a hydrogen peroxide (H2O2) stimulus.	tmpzr1t_l9r_go_relaxed.owl								dph	2012-01-12T11:39:10Z					biological_process											owl:Class	
GO:0070301	biolink:NamedThing	cellular response to hydrogen peroxide	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrogen peroxide (H2O2) stimulus.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0030724	biolink:NamedThing	testicular fusome organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the fusome of testicular cells, an organelle derived from the spectrosome.	tmpzr1t_l9r_go_relaxed.owl	testicular fusome organisation|testicular fusome organization and biogenesis													biological_process											owl:Class	
GO:0098866	biolink:NamedThing	multivesicular body fusion to apical plasma membrane	The fusion of the membrane of a multivesicular body with the apical plasma membrane, resulting in release of exosomes from the cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1990182	biolink:NamedThing	exosomal secretion	The process whereby a membrane-bounded vesicle is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane.	tmpzr1t_l9r_go_relaxed.owl	exosomal protein secretion|extracellular vesicular exosome secretion|multi-vesicular body fusion with plasma membrane|secretion of exosome|exosomal secretory pathway							hjd	2013-09-04T21:08:14Z					biological_process											owl:Class	
GO:0042906	biolink:NamedThing	xanthine transport	The directed movement of xanthine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Xanthine (2,6-dihydroxypurine) is a purine formed in the metabolic breakdown of guanine, but is not present in nucleic acids.	tmpzr1t_l9r_go_relaxed.owl	xanthine transmembrane transport													biological_process											owl:Class	
GO:0031954	biolink:NamedThing	positive regulation of protein autophosphorylation	Any process that activates or increases the frequency, rate or extent of the phosphorylation by a protein of one or more of its own residues.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of protein amino acid autophosphorylation|up regulation of protein amino acid autophosphorylation|positive regulation of protein amino acid autophosphorylation|activation of protein amino acid autophosphorylation|stimulation of protein amino acid autophosphorylation|upregulation of protein amino acid autophosphorylation													biological_process											owl:Class	
GO:0110104	biolink:NamedThing	mRNA alternative polyadenylation	The process of generating multiple mRNA molecules with variable 3'-end length formation from a given pre-mRNA by differential use of cleavage and polyadenylation signals (pA signals).	tmpzr1t_l9r_go_relaxed.owl								kmv	2018-03-27T19:26:56Z					biological_process											owl:Class	
GO:0060010	biolink:NamedThing	Sertoli cell fate commitment	The process in which the cellular identity of Sertoli cells is acquired and determined.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0019087	biolink:NamedThing	transformation of host cell by virus	A virus-induced cellular transformation resulting in immortalized cells, or cells capable of indefinite replication.	tmpzr1t_l9r_go_relaxed.owl	viral transformation|transformation of host cell|viral immortalization|host cell transformation|viral transformation of host cell|immortalization of host cell by virus|host cell immortalization|immortalization of host cell				Wikipedia:Viral_transformation							GO:0020021|GO:0019088		biological_process											owl:Class	
GO:0035072	biolink:NamedThing	ecdysone-mediated induction of salivary gland cell autophagic cell death	Any process induced by ecdysone that directly activates salivary gland programmed cell death during salivary gland histolysis.	tmpzr1t_l9r_go_relaxed.owl	ecdysone-mediated induction of autophagic cell death of salivary gland cells|ecdysone-mediated induction of salivary gland cell programmed cell death by autophagy|ecdysone-mediated induction of programmed cell death of salivary gland cells by autophagy													biological_process											owl:Class	
GO:0035071	biolink:NamedThing	salivary gland cell autophagic cell death	The stage-specific programmed cell death of salivary gland cells during salivary gland histolysis.	tmpzr1t_l9r_go_relaxed.owl	salivary gland cell death|programmed cell death of salivary gland cells by autophagy|autophagic cell death of salivary gland cells|salivary gland cell programmed cell death by autophagy													biological_process											owl:Class	
GO:0010063	biolink:NamedThing	positive regulation of trichoblast fate specification	Any process that induces or promotes trichoblast fate specification.	tmpzr1t_l9r_go_relaxed.owl	up regulation of trichoblast fate|activation of trichoblast fate|stimulation of trichoblast fate|up-regulation of trichoblast fate|upregulation of trichoblast fate													biological_process											owl:Class	
GO:1903953	biolink:NamedThing	negative regulation of voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization	Any process that stops, prevents or reduces the frequency, rate or extent of voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization|down regulation of voltage-gated potassium channel activity involved in atrial cardiomyocyte action potential repolarization|down regulation of voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization|downregulation of voltage-gated potassium channel activity involved in atrial cardiomyocyte action potential repolarization|down-regulation of voltage-gated potassium channel activity involved in atrial cardiomyocyte action potential repolarization|negative regulation of voltage-gated potassium channel activity involved in atrial cardiomyocyte action potential repolarization|inhibition of voltage-gated potassium channel activity involved in atrial cardiomyocyte action potential repolarization|downregulation of voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization|inhibition of voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization							nc	2015-02-24T10:32:16Z					biological_process											owl:Class	
GO:0045282	biolink:NamedThing	plasma membrane succinate dehydrogenase complex	A multimeric complex which consists of flavoprotein (subunit A ; InterPro:IPR003952), iron-sulfur protein (subunit B) and membrane-bound cytochrome b560 (subunit C; InterPro:IPR000701). In some Archaea, the membrane-bound subunits (C or C and D) do not necessarily contain heme. Membrane-bound subunits can bind/react with quinones. Examples of this component are found in Bacterial species.	tmpzr1t_l9r_go_relaxed.owl	succinate dehydrogenase complex													cellular_component											owl:Class	
GO:0002415	biolink:NamedThing	immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor	The process of transporting polymeric IgA and polymeric IgM immunoglobulin, via transcytosis mediated by the polymeric immunoglobulin receptor (pIgR), from the basolateral surface to apical surface of an epithelial cell. At the apical surface the immunoglobulin binding portion of the pIgRis cleaved and remains bound to the transported immunoglobulin as secretory component (SC). The same process is used for the transport and excretion of IgA immune complexes to the luminal surface of the mucosa.	tmpzr1t_l9r_go_relaxed.owl	antibody transcytosis mediated by pIgR|immunoglobulin transcytosis mediated by pIgR													biological_process											owl:Class	
GO:0070498	biolink:NamedThing	interleukin-1-mediated signaling pathway	A series of molecular signals initiated by the binding of interleukin-1 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.	tmpzr1t_l9r_go_relaxed.owl	IL-1-mediated signaling pathway|interleukin-1-mediated signalling pathway|interleukin-1 beta-mediated signaling pathway|interleukin-1 alpha-mediated signaling pathway|IL-1 beta-mediated signaling pathway|IL-1 alpha-mediated signaling pathway													biological_process											owl:Class	
GO:0005658	biolink:NamedThing	alpha DNA polymerase:primase complex	A complex of four polypeptides, comprising large and small DNA polymerase alpha subunits and two primase subunits, which are capable of catalyzing the synthesis of an RNA primer on the lagging strand of replicating DNA and the subsequent synthesis of a smal stretch of DNA. The smaller of the two primase subunits alone can catalyze oligoribonucleotide synthesis.	tmpzr1t_l9r_go_relaxed.owl	heterotetrameric polymerase alpha holoenzyme|primosome|DNA polymerase alpha:primase complex|pol-prim													cellular_component											owl:Class	
GO:0034348	biolink:NamedThing	type III interferon receptor activity	Combining with a type III interferon and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. Interferon lambda is the only member of the type III interferon found so far.	tmpzr1t_l9r_go_relaxed.owl	interferon-lambda receptor activity					Note that IL-28A, IL-28B, and IL-29 are types of interferon-lambda.								molecular_function											owl:Class	
GO:0034347	biolink:NamedThing	type III interferon binding	Binding to a type III interferon. Interferon lambda is the only member of the type III interferon found so far.	tmpzr1t_l9r_go_relaxed.owl	interferon-lambda binding					Note that IL-28A, IL-28B, and IL-29 are types of interferon-lambda.								molecular_function											owl:Class	
GO:1902433	biolink:NamedThing	positive regulation of water channel activity involved in maintenance of lens transparency	Any positive regulation of water channel activity that is involved in maintenance of lens transparency.	tmpzr1t_l9r_go_relaxed.owl	up regulation of water channel activity involved in preservation of lens transparency|upregulation of aquaporin involved in preservation of lens transparency|up regulation of aquaporin involved in maintenance of lens transparency|up regulation of aquaporin involved in preservation of lens transparency|aquaporin activation involved in preservation of lens transparency|up-regulation of water channel activity involved in maintenance of lens transparency|up-regulation of water channel activity involved in maintenance of ocular lens transparency|positive regulation of aquaporin involved in maintenance of ocular lens transparency|positive regulation of water channel activity involved in preservation of lens transparency|up regulation of aquaporin involved in maintenance of ocular lens transparency|aquaporin activation involved in maintenance of lens transparency|upregulation of water channel activity involved in maintenance of ocular lens transparency|up-regulation of water channel activity involved in preservation of lens transparency|upregulation of water channel activity involved in maintenance of lens transparency|activation of water channel activity involved in maintenance of lens transparency|aquaporin activation involved in maintenance of ocular lens transparency|upregulation of aquaporin involved in maintenance of ocular lens transparency|up-regulation of aquaporin involved in maintenance of ocular lens transparency|up-regulation of aquaporin involved in preservation of lens transparency|positive regulation of aquaporin involved in preservation of lens transparency|positive regulation of water channel activity involved in maintenance of ocular lens transparency|up-regulation of aquaporin involved in maintenance of lens transparency|activation of water channel activity involved in maintenance of ocular lens transparency|activation of water channel activity involved in preservation of lens transparency|up regulation of water channel activity involved in maintenance of ocular lens transparency|upregulation of aquaporin involved in maintenance of lens transparency|activation of aquaporin involved in maintenance of lens transparency|up regulation of water channel activity involved in maintenance of lens transparency|activation of aquaporin involved in preservation of lens transparency|activation of aquaporin involved in maintenance of ocular lens transparency|upregulation of water channel activity involved in preservation of lens transparency|positive regulation of aquaporin involved in maintenance of lens transparency							bf	2013-10-02T12:58:00Z					biological_process											owl:Class	
GO:0036438	biolink:NamedThing	maintenance of lens transparency	A homeostatic process in which the lens is maintained in a highly refractive, transparent state to allow for optimal focusing of light on the retina.	tmpzr1t_l9r_go_relaxed.owl	maintenance of ocular lens transparency|preservation of lens transparency							bf	2013-09-23T13:51:09Z					biological_process											owl:Class	
GO:1905391	biolink:NamedThing	regulation of protein localization to cell division site involved in cell separation after cytokinesis	Any regulation of protein localization to cell division site that is involved in cell separation after cytokinesis.	tmpzr1t_l9r_go_relaxed.owl	regulation of protein localisation to cell division site involved in cytokinetic cell separation|regulation of protein localisation to cell division site involved in cell separation after cytokinesis|regulation of protein localisation to cell division site involved in mitotic cytokinetic cell separation|regulation of protein localisation to cell division site involved in cell separation following cytokinesis							vw	2016-08-22T09:40:47Z					biological_process											owl:Class	
GO:0000331	biolink:NamedThing	contractile vacuole	A specialized vacuole of eukaryotic cells, especially Protozoa, that fills with water from the cytoplasm and then discharges this externally by the opening of contractile vacuole pores. One of its functions is osmoregulatory.	tmpzr1t_l9r_go_relaxed.owl	central bladder|central vacuole				Wikipedia:Contractile_vacuole									cellular_component											owl:Class	
GO:0062159	biolink:NamedThing	contractile vacuole complex	A non-membrane-bounded organelle of eukaryotic cells, especially Protozoa, that fills with water from the cytoplasm and then discharges this externally. One of its functions is osmoregulatory.	tmpzr1t_l9r_go_relaxed.owl	CVC							dph	2019-09-26T14:20:14Z					cellular_component											owl:Class	
GO:0031424	biolink:NamedThing	keratinization	The process in which the cytoplasm of the outermost cells of the vertebrate epidermis is replaced by keratin. Keratinization occurs in the stratum corneum, feathers, hair, claws, nails, hooves, and horns.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0032740	biolink:NamedThing	positive regulation of interleukin-17 production	Any process that activates or increases the frequency, rate, or extent of production of any member of the interleukin-17 family of cytokines.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of interleukin-17 secretion|upregulation of interleukin-17 production|activation of interleukin-17 production|positive regulation of Cytotoxic T-lymphocyte-associated antigen 8 production|positive regulation of IL-17 production|positive regulation of CTLA-8 production|up-regulation of interleukin-17 production|positive regulation of interleukin-17 biosynthetic process|stimulation of interleukin-17 production|up regulation of interleukin-17 production											GO:0045380|GO:1905078		biological_process											owl:Class	
GO:0042979	biolink:NamedThing	ornithine decarboxylase regulator activity	Binds to and modulates the activity of the enzyme ornithine decarboxylase.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0097102	biolink:NamedThing	endothelial tip cell fate specification	The process involved in the specification of identity of an endothelial tip cell. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment. An endothelial tip cell is a specialized endothelial cell localized to the leading edge of an angiogenic sprout that senses extracellular signals and guides the directed growth of blood vessels.	tmpzr1t_l9r_go_relaxed.owl	angiogenic tip cell fate specification							pr	2011-07-27T10:29:00Z					biological_process											owl:Class	
GO:0140397	biolink:NamedThing	versiconal hemiacetal acetate esterase activity	Catalyzes the reactions: versiconal hemiacetal acetate + H(2)O <=> versiconal + acetate, as well as versiconol acetate + H(2)O <=> versiconol + acetate.	tmpzr1t_l9r_go_relaxed.owl					RHEA:35715|EC:3.1.1.94|MetaCyc:RXN-9493|MetaCyc:RXN-9488			pg	2019-11-29T10:14:17Z					molecular_function											owl:Class	
GO:0055119	biolink:NamedThing	relaxation of cardiac muscle	The process in which the extent of cardiac muscle contraction is reduced.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0001980	biolink:NamedThing	regulation of systemic arterial blood pressure by ischemic conditions	The process that modulates blood pressure by the detection of carbon dioxide levels in the brain stem. Increased levels activate the sympathetic vasoconstrictor mechanism increasing the force with which blood flows through the circulatory system.	tmpzr1t_l9r_go_relaxed.owl	ischemic control of blood pressure|CNS ischemic response|ischemic regulation of systemic arterial blood pressure													biological_process											owl:Class	
GO:0042557	biolink:NamedThing	eukaryotic elongation factor-2 kinase activator activity	Binds to and increases the activity of the enzyme eukaryotic elongation factor-2 kinase.	tmpzr1t_l9r_go_relaxed.owl	eEF-2 kinase activator													molecular_function											owl:Class	
GO:0000800	biolink:NamedThing	lateral element	A proteinaceous core found between sister chromatids during meiotic prophase.	tmpzr1t_l9r_go_relaxed.owl	axial element					In species that have a synaptonemal complex, the lateral elements are part of this complex.  S.pombe is an example of a species that lacks a  (canonical) synaptonemal complex, but still has lateral elements.								cellular_component											owl:Class	
GO:0000795	biolink:NamedThing	synaptonemal complex	A proteinaceous scaffold found between homologous chromosomes during meiosis. It consists of 2 lateral elements and a central element, all running parallel to each other.  Transverse filaments connect the lateral elements to the central element.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Synaptonemal_complex							GO:0005716		cellular_component											owl:Class	
GO:0050115	biolink:NamedThing	myosin-light-chain-phosphatase activity	Catalysis of the reaction: myosin light-chain phosphate + H2O = myosin light chain + phosphate.	tmpzr1t_l9r_go_relaxed.owl	myosin-light-chain phosphatase activity|myosin-light-chain-phosphate phosphohydrolase activity|myosin light chain kinase phosphatase activity|protein phosphatase 2A|myosin light-chain kinase phosphatase activity|[Myosin light-chain]-phosphatase activity				Reactome:R-HSA-419232|EC:3.1.3.53|MetaCyc:MYOSIN-LIGHT-CHAIN-PHOSPHATASE-RXN									molecular_function											owl:Class	
GO:0036242	biolink:NamedThing	glutamate catabolic process to succinate via 2-oxoglutarate-dependent GABA-transaminase activity	The chemical reactions and pathways resulting in the breakdown of glutamate into succinate, that includes the conversion of 4-aminobutyrate to succinate semialdehyde by the 2-oxoglutarate-dependent gamma aminobutyrate (GABA) transaminase.	tmpzr1t_l9r_go_relaxed.owl	glutamate degradation via gamma aminobutyrate transaminase activity				MetaCyc:PWY-4321|MetaCyc:PWY3O-210	While mammals only have 2-oxoglutarate-dependent GABA-transaminase, both 2-oxoglutarate-dependent and pyruvate-dependent GABA-transaminase activities have been detected in plants.		bf	2012-05-23T02:28:33Z					biological_process											owl:Class	
GO:0034386	biolink:NamedThing	4-aminobutyrate:2-oxoglutarate transaminase activity	Catalysis of the reaction: 4-aminobutanoate + 2-oxoglutarate = succinate semialdehyde + L-glutamate.	tmpzr1t_l9r_go_relaxed.owl	4-aminobutyric acid 2-ketoglutaric acid aminotransferase activity|4-aminobutyrate-2-oxoglutarate transaminase activity|gamma-aminobutyric acid-alpha-ketoglutaric acid aminotransferase activity|gamma-aminobutyrate:alpha-oxoglutarate aminotransferase activity|GABA-2-oxoglutarate aminotransferase activity|GABA-alpha-ketoglutarate aminotransferase activity|GABA-alpha-ketoglutaric acid transaminase activity|4-aminobutyrate-2-ketoglutarate aminotransferase activity|gamma-aminobutyrate-alpha-ketoglutarate transaminase activity|GABA-oxoglutarate aminotransferase activity|4-aminobutyrate-2-oxoglutarate aminotransferase activity|gamma-aminobutyric acid-2-oxoglutarate transaminase activity|gamma-aminobutyric acid-alpha-ketoglutarate transaminase activity|gamma-aminobutyrate-alpha-ketoglutarate aminotransferase activity|4-aminobutanoate:2-oxoglutarate aminotransferase activity|GABA-2-oxoglutarate transaminase activity|GABA-alpha-oxoglutarate aminotransferase activity|GABA-alpha-ketoglutarate transaminase activity|GABA-oxoglutarate transaminase activity				EC:2.6.1.19|MetaCyc:GABATRANSAM-RXN									molecular_function											owl:Class	
GO:0061456	biolink:NamedThing	mesenchymal stem cell migration involved in uteric bud morphogenesis	The orderly movement of a mesenchymal stem cell from one site to another contributing to the shaping of the ureteric bud. A mesenchymal stem cell, or MSC, is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells.	tmpzr1t_l9r_go_relaxed.owl								dph	2012-08-22T17:19:22Z					biological_process											owl:Class	
GO:0060675	biolink:NamedThing	ureteric bud morphogenesis	The process in which the ureteric bud is generated and organized.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-06-02T01:31:41Z					biological_process											owl:Class	
GO:2000221	biolink:NamedThing	negative regulation of pseudohyphal growth	Any process that stops, prevents, or reduces the frequency, rate or extent of pseudohyphal growth.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-11-03T04:37:00Z					biological_process											owl:Class	
GO:1900072	biolink:NamedThing	positive regulation of sulfite transport	Any process that activates or increases the frequency, rate or extent of sulfite transport.	tmpzr1t_l9r_go_relaxed.owl	upregulation of sulphite transport|activation of sulphite transport|up-regulation of sulphite transport|upregulation of sulfite transport|activation of sulfite transport|up regulation of sulphite transport|up regulation of sulfite transport|up-regulation of sulfite transport|positive regulation of sulphite transport							dph	2012-01-26T08:41:16Z					biological_process											owl:Class	
GO:0060657	biolink:NamedThing	regulation of mammary gland cord elongation by mammary fat precursor cell-epithelial cell signaling	Any process that modulates the rate, frequency, or extent of mammary gland cord elongation as a result of a signal being created by a mesenchymal cell that is a precursor to the mammary fat and its subsequent reception and interpretation by an mammary cord epithelial cell.	tmpzr1t_l9r_go_relaxed.owl	regulation of mammary gland cord elongation by mammary fat precursor cell-epithelial cell signalling							dph	2009-05-29T09:43:08Z					biological_process											owl:Class	
GO:0010054	biolink:NamedThing	trichoblast differentiation	The process in which a relatively unspecialized cell acquires the specialized features of a trichoblast, a root epidermal cell that will give rise to a root hair.	tmpzr1t_l9r_go_relaxed.owl	trichoblast cell differentiation													biological_process											owl:Class	
GO:0036019	biolink:NamedThing	endolysosome	An transient hybrid organelle formed by fusion of a late endosome with a lysosome, and in which active degradation takes place.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-10-13T02:35:13Z					cellular_component											owl:Class	
GO:0031948	biolink:NamedThing	positive regulation of glucocorticoid biosynthetic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glucocorticoids.	tmpzr1t_l9r_go_relaxed.owl	activation of glucocorticoid biosynthetic process|upregulation of glucocorticoid biosynthetic process|up regulation of glucocorticoid biosynthetic process|up-regulation of glucocorticoid biosynthetic process|stimulation of glucocorticoid biosynthetic process													biological_process											owl:Class	
GO:0021880	biolink:NamedThing	Notch signaling pathway involved in forebrain neuron fate commitment	The series of molecular signals initiated by binding of an extracellular ligand to a Notch receptor on the surface of the target cell that contributes to the commitment of a neuroblast to a neuronal fate. The neuron will reside in the forebrain.	tmpzr1t_l9r_go_relaxed.owl	Notch signalling pathway involved in forebrain neuron fate commitment													biological_process											owl:Class	
GO:0061438	biolink:NamedThing	renal system vasculature morphogenesis	The process in which the renal system vasculature is generated and organized. Morphogenesis pertains to the creation of form.	tmpzr1t_l9r_go_relaxed.owl								dph	2012-03-08T12:21:56Z					biological_process											owl:Class	
GO:0060083	biolink:NamedThing	smooth muscle contraction involved in micturition	The process leading to shortening and/or development of tension in the urinary bladder smooth muscle tissue involved in the expulsion urine from the body.	tmpzr1t_l9r_go_relaxed.owl	urinary bladder smooth muscle contraction involved in micturition|smooth muscle contraction involved in urination													biological_process											owl:Class	
GO:0042020	biolink:NamedThing	interleukin-23 receptor activity	Combining with interleukin-23 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	IL-23R|IL-23 receptor activity													molecular_function											owl:Class	
GO:0038155	biolink:NamedThing	interleukin-23-mediated signaling pathway	A series of molecular signals initiated by the binding of interleukin-23 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.	tmpzr1t_l9r_go_relaxed.owl	interleukin-23-mediated signalling pathway|IL-23-mediated signaling pathway							bf	2012-05-11T11:49:56Z					biological_process											owl:Class	
GO:0009640	biolink:NamedThing	photomorphogenesis	The control of plant growth, development, and differentiation by the duration and nature of light, independent of photosynthesis.	tmpzr1t_l9r_go_relaxed.owl	plant development in response to light				Wikipedia:Photomorphogenesis									biological_process											owl:Class	
GO:0034088	biolink:NamedThing	maintenance of mitotic sister chromatid cohesion	The process in which the association between sister chromatids of a replicated chromosome is maintained as chromosomes condense, attach to the spindle in a bipolar orientation, and congress to the metaphase plate during a mitotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl	mitotic cohesion stability													biological_process											owl:Class	
GO:0021628	biolink:NamedThing	olfactory nerve formation	The process that gives rise to the olfactory nerve. This process pertains to the initial formation of a structure from unspecified parts. The olfactory nerve is a collection of sensory nerve rootlets that extend down from the olfactory bulb to the olfactory mucosa of the upper parts of the nasal cavity. This nerve conducts odor information to the brainstem.	tmpzr1t_l9r_go_relaxed.owl	CN I biosynthesis|CN I formation													biological_process											owl:Class	
GO:0021627	biolink:NamedThing	olfactory nerve morphogenesis	The process in which the anatomical structure of the olfactory nerve is generated and organized. The olfactory nerve is a collection of sensory nerve rootlets that extend down from the olfactory bulb to the olfactory mucosa of the upper parts of the nasal cavity. This nerve conducts odor information to the brainstem.	tmpzr1t_l9r_go_relaxed.owl	CN I morphogenesis													biological_process											owl:Class	
GO:0120059	biolink:NamedThing	negative regulation of small intestinal transit	Any process that decreases the frequency, rate or extent of any small intestinal transit process, the migration of ingested material along the length of the small intestine.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of small intestine transit|negative regulation of small bowel transit							krc	2017-06-13T20:58:23Z					biological_process											owl:Class	
GO:0055002	biolink:NamedThing	striated muscle cell development	The process whose specific outcome is the progression of a striated muscle cell over time, from its formation to the mature structure. Striated muscle cells contain fibers that are divided by transverse bands into striations, and cardiac and skeletal muscle are types of striated muscle.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0050253	biolink:NamedThing	retinyl-palmitate esterase activity	Catalysis of the reaction: retinyl palmitate + H2O = retinol + palmitate + H+.	tmpzr1t_l9r_go_relaxed.owl	retinyl palmitate hydrolyase activity|retinyl-palmitate palmitohydrolase activity|retinyl ester hydrolase activity|retinyl palmitate hydrolase activity				Reactome:R-HSA-975593|MetaCyc:RETINYL-PALMITATE-ESTERASE-RXN|Reactome:R-HSA-2404133|Reactome:R-HSA-975594|EC:3.1.1.21|RHEA:21508|Reactome:R-HSA-8848355|KEGG_REACTION:R02368									molecular_function											owl:Class	
GO:0072171	biolink:NamedThing	mesonephric tubule morphogenesis	The process in which the anatomical structures of a mesonephric tubule are generated and organized. A mesonephric tubule is an epithelial tube that is part of the mesonephros.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-02-26T02:02:13Z					biological_process											owl:Class	
GO:0070162	biolink:NamedThing	adiponectin secretion	The regulated release of adiponectin, a protein hormone, by adipose tissue.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1990073	biolink:NamedThing	perforation plate	A cell wall part that is the part of a wall of a vessel member and bears one or more openings (perforations).	tmpzr1t_l9r_go_relaxed.owl						Part of a vessel member (PO:0002003). May be simple, with one perforation, or multiperforate, with more than one perforation. Perforation plates are usually on the end walls of a cell, but may also be on the side walls.		tb	2013-03-29T00:53:28Z					cellular_component											owl:Class	
GO:0061854	biolink:NamedThing	positive regulation of neuroblast migration	Any process that activates or increases the frequency, rate or extent of neuroblast migration.	tmpzr1t_l9r_go_relaxed.owl								dph	2017-03-08T18:22:30Z					biological_process											owl:Class	
GO:1990395	biolink:NamedThing	meiotic spindle pole body organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the meiotic spindle pole body.	tmpzr1t_l9r_go_relaxed.owl								tb	2014-06-06T01:41:05Z					biological_process											owl:Class	
GO:0008597	biolink:NamedThing	calcium-dependent protein serine/threonine phosphatase regulator activity	Binds to and modulates of the activity of the enzyme calcium-dependent protein serine/threonine phosphatase.	tmpzr1t_l9r_go_relaxed.owl	calcium-dependent protein serine/threonine phosphatase, intrinsic regulator activity				Reactome:R-HSA-139906									molecular_function											owl:Class	
GO:0048475	biolink:NamedThing	coated membrane	A single or double lipid bilayer with any of several different proteinaceous coats that can associate with membranes. Membrane coats include those formed by clathrin plus an adaptor complex, the COPI and COPII complexes.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0090489	biolink:NamedThing	L-tryptophan,NADPH:oxygen oxidoreductase (N-hydroxylating, decarboxylating)	Catalyzes the multi-step reaction: L-Tryptophan + 2 Oxygen + 2 NADPH + 2 H+ = Indole-3-acetaldehyde oxime + 3 H2O + 2 NADP+ + CO2. The individual reactions are: (1a) L-tryptophan + O2 + NADPH + H+ = N-hydroxy-L-tryptophan + NADP+ + H2O,(1b) N-hydroxy-L-tryptophan + O2 + NADPH + H+ = N,N-dihydroxy-L-tryptophan + NADP+ + H2O, and (1c) N,N-dihydroxy-L-tryptophan = (E)-indol-3-ylacetaldoxime + CO2 + H2O.	tmpzr1t_l9r_go_relaxed.owl	tryptophan N-monooxygenase activity							tb	2012-10-16T16:22:19Z					molecular_function											owl:Class	
GO:0090490	biolink:NamedThing	L-tryptophan,NADPH:oxygen oxidoreductase (N-hydroxylating)	Catalyzes the reaction: L-Tryptophan + Oxygen + NADPH + H+ = N-Hydroxy-L-tryptophan + NADP+ + H2O.	tmpzr1t_l9r_go_relaxed.owl								tb	2012-10-16T16:27:19Z					molecular_function											owl:Class	
GO:0009925	biolink:NamedThing	basal plasma membrane	The region of the plasma membrane located at the basal end of the cell. Often used in reference to animal polarized epithelial membranes, where the basal membrane is the part attached to the extracellular matrix, or in plant cells, where the basal membrane is defined with respect to the zygotic axis.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0097356	biolink:NamedThing	perinucleolar compartment	The perinucleolar compartment (PNC) is a subnuclear structure associated with, but structurally distinct from, the nucleolus. The PNC contains large amounts of the heterogeneous nuclear ribonucleoprotein complex (hnRNP) called hnRNP 1 (PTB). Many RNA binding proteins as well as RNA polymerase III transcripts are highly enriched in this compartment. PTB and pol III transcripts are required for the integrity of the PNC.	tmpzr1t_l9r_go_relaxed.owl	perinucleolar region							pr	2012-07-03T05:11:01Z					cellular_component											owl:Class	
GO:0150107	biolink:NamedThing	positive regulation of protein localization to cell-cell junction	Any process that activates or increases the frequency, rate or extent of protein localization to cell-cell junction.	tmpzr1t_l9r_go_relaxed.owl								bc	2019-06-11T11:23:58Z					biological_process											owl:Class	
GO:0140505	biolink:NamedThing	regulation of microlipophagy	Any process that modulates the frequency, rate or extent of microlipophagy, the microautophagy-mediated direct internalization of lipid droplets into a lysosome-like vacuole during nutrient depletion.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/19869						pg	2020-08-14T12:56:29Z					biological_process											owl:Class	
GO:0140504	biolink:NamedThing	microlipophagy	Microautophagy-mediated direct internalization of lipid droplets into a lysosome-like vacuole during nutrient depletion, such as during the transition to stationary phase or in response to nutrient limitation. Microlipophagy is mediated by the formation of sterol-enriched vacuolar microdomains at sites of engulfment. Initiation of microautophagy is defined as the point where liquid-ordered microdomains are formed at sites of engulfment, that requires S. cerevisiae Atg32p and Atg21p, as well as Niemann-Pick type C (NPC) sterol transporter proteins, Ncr1p and Npc2p. This is followed by redistribution of Atg14p from ER exit sites onto liquid-ordered vacuole membrane domains through interaction with stabilized AMP-activated protein kinase (AMPK), and together with Atg6p facilities docking and internalization of lipid droplets (LDs) at sites of invagination.	tmpzr1t_l9r_go_relaxed.owl	lipid droplet autophagy	https://github.com/geneontology/go-ontology/issues/19869						pg	2020-08-14T12:53:43Z					biological_process											owl:Class	
GO:0097563	biolink:NamedThing	left middle basal body pair	Set of two basal bodies found in Giardia species (trophozoite stage). It comprises the caudal and posteriolateral basal bodies located to the right of the left nucleus of the trophozoite when viewed dorsally.	tmpzr1t_l9r_go_relaxed.owl						Due to the asymmetric nature of the Giardia trophozoite, this term is defined spatially as the trophozoite is viewed from the dorsal side, with the two nuclei dorsal to the ventral disc, and the ventral disc toward the anterior.		pr	2014-02-05T16:11:14Z					cellular_component											owl:Class	
GO:0071811	biolink:NamedThing	positive regulation of fever generation by positive regulation of prostaglandin biosynthesis	Any process that increases the rate or extent of fever generation via positive regulation of the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of prostaglandin.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-09-03T05:10:05Z					biological_process											owl:Class	
GO:0048855	biolink:NamedThing	adenohypophysis morphogenesis	The process in which the anatomical structures of the adenohypophysis are generated and organized. The adenohypophysis is the anterior part of the pituitary. It secretes a variety of hormones and its function is regulated by the hypothalamus.	tmpzr1t_l9r_go_relaxed.owl	anterior pituitary morphogenesis|adenophysis morphogenesis|anterior pituitary gland morphogenesis													biological_process											owl:Class	
GO:0042680	biolink:NamedThing	compound eye cone cell fate determination	The process in which a cell becomes capable of differentiating autonomously into a compound eye cone cell regardless of its environment; upon determination, the cell fate cannot be reversed.	tmpzr1t_l9r_go_relaxed.owl												GO:0042677		biological_process											owl:Class	
GO:0038066	biolink:NamedThing	p38MAPK cascade	An intracellular protein kinase cascade containing at least a p38 MAPK, a MAPKK and a MAP3K. The cascade can also contain an additional tier: the upstream MAP4K. The kinases in each tier phosphorylate and activate the kinases in the downstream tier to transmit a signal within a cell.	tmpzr1t_l9r_go_relaxed.owl	p38 cascade|p38 MAPK cascade							bf	2012-01-25T11:51:24Z					biological_process											owl:Class	
GO:0070129	biolink:NamedThing	regulation of mitochondrial translation	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA in a mitochondrion.	tmpzr1t_l9r_go_relaxed.owl	regulation of mitochondrial protein anabolism|regulation of mitochondrial protein biosynthesis|regulation of mitochondrial protein formation|regulation of mitochondrial protein synthesis													biological_process											owl:Class	
GO:0032543	biolink:NamedThing	mitochondrial translation	The chemical reactions and pathways resulting in the formation of a protein in a mitochondrion. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein; the mitochondrion has its own ribosomes and transfer RNAs, and uses a genetic code that differs from the nuclear code.	tmpzr1t_l9r_go_relaxed.owl	mitochondrial protein biosynthesis|mitochondrial protein anabolism|mitochondrial protein formation|mitochondrial protein synthesis|mitochondrial protein translation													biological_process											owl:Class	
GO:1903379	biolink:NamedThing	regulation of mitotic chromosome condensation	Any process that modulates the frequency, rate or extent of mitotic chromosome condensation.	tmpzr1t_l9r_go_relaxed.owl								al	2014-08-26T13:57:13Z					biological_process											owl:Class	
GO:1905258	biolink:NamedThing	regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway	Any process that modulates the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to nitrosative stress.	tmpzr1t_l9r_go_relaxed.owl	regulation of intrinsic apoptotic signaling pathway in response to nitrosative stress|regulation of nitrosative stress-induced apoptosis							bf	2016-06-13T17:04:59Z					biological_process											owl:Class	
GO:0035288	biolink:NamedThing	anterior head segmentation	Partitioning the insect head anlage into procephalic (labral, (ocular), antennal and intercalary) segments. The procephalic segments lie anterior to the gnathal (posterior head) segments, and are pattered by different segmentation gene cascades to the abdominal, thoracic and posterior head (gnathal) segments.	tmpzr1t_l9r_go_relaxed.owl	procephalic segmentation					See also the fly_anatomy.ontology term 'procephalic segment ; FBbt:00000007' and its children.								biological_process											owl:Class	
GO:0015126	biolink:NamedThing	canalicular bile acid transmembrane transporter activity	The directed movement of bile acid and bile salts out of a hepatocyte and into the bile canaliculus by means of an agent such as a transporter or pore. Bile canaliculi are the thin tubes formed by hepatocyte membranes. Bile acids are any of a group of steroid carboxylic acids occurring in bile, where they are present as the sodium salts of their amides with glycine or taurine.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0015722	biolink:NamedThing	canalicular bile acid transport	Enables the transfer of bile acid from one side of a hepatocyte plasma membrane into a bile canaliculus. Bile canaliculi are the thin tubes formed by hepatocyte membranes. Bile acids are any of a group of steroid carboxylic acids occurring in bile, where they are present as the sodium salts of their amides with glycine or taurine.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0038193	biolink:NamedThing	thromboxane A2 signaling pathway	The series of molecular signals generated as a consequence of thromboxane A2 binding to a cell surface receptor. The pathway proceeds with the receptor transmitting the signal to a heterotrimeric G-protein complex and ends with regulation of a downstream cellular process, e.g. transcription.	tmpzr1t_l9r_go_relaxed.owl	TXA(2) receptor signaling|TXA2 signaling							bf	2013-09-02T16:07:01Z					biological_process											owl:Class	
GO:1902674	biolink:NamedThing	right posteriolateral basal body	Any ciliary basal body that is part of a right posteriolateral flagellum found in Giardia species (trophozoite stage).	tmpzr1t_l9r_go_relaxed.owl	cilial basal body of right posterolateral flagellum|ciliary basal body of right posterolateral flagellum|cilium basal body of right posteriolateral flagellum|microtubule basal body of right posterolateral flagellum|cilium basal body of right posterolateral flagellum|right posteriolateral flagellum ciliary basal body|cilial basal body of right posteriolateral cilium|microtubule basal body of right posteriolateral cilium|microtubule basal body of right posteriolateral flagellum|ciliary basal body of right posterolateral cilium|cilial basal body of right posterolateral cilium|cilial basal body of right posteriolateral flagellum|microtubule basal body of right posterolateral cilium|ciliary basal body of right posteriolateral flagellum|ciliary basal body of right posteriolateral cilium|cilium basal body of right posteriolateral cilium|cilium basal body of right posterolateral cilium					Note that we deem cilium and microtubule-based flagellum to be equivalent. Also note that, due to the asymmetric nature of the Giardia trophozoite, this term is defined spatially as the trophozoite is viewed from the dorsal side, with the two nuclei dorsal to the ventral disc, and the ventral disc toward the anterior.		pr	2014-02-05T14:52:04Z					cellular_component											owl:Class	
GO:1902365	biolink:NamedThing	positive regulation of protein localization to spindle pole body	Any process that activates or increases the frequency, rate or extent of protein localization to spindle pole body.	tmpzr1t_l9r_go_relaxed.owl	up regulation of protein localisation to spindle pole body|up-regulation of protein localization to spindle pole body|up-regulation of protein localisation to spindle pole body|activation of protein localisation to spindle pole body|positive regulation of protein localisation to spindle pole body|activation of protein localization to spindle pole body|up regulation of protein localization to spindle pole body|upregulation of protein localisation to spindle pole body|upregulation of protein localization to spindle pole body							vw	2013-08-15T16:38:31Z					biological_process											owl:Class	
GO:0044155	biolink:NamedThing	host caveola	A small pit, depression, or invagination, such as any of the minute pits or incuppings of the host cell membrane formed during pinocytosis, that communicates with the outside of a host cell and extends inward, indenting the host cytoplasm and the host cell membrane. Such caveolae may be pinched off to form free vesicles within the host cytoplasm. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl								jl	2009-08-11T04:00:55Z					cellular_component											owl:Class	
GO:1904189	biolink:NamedThing	positive regulation of transformation of host cell by virus	Any process that activates or increases the frequency, rate or extent of transformation of host cell by virus.	tmpzr1t_l9r_go_relaxed.owl	upregulation of transformation of host cell by virus|up regulation of viral transformation of host cell|up-regulation of transformation of host cell by virus|activation of viral transformation of host cell|upregulation of viral transformation of host cell|activation of transformation of host cell by virus|positive regulation of viral transformation of host cell|positive regulation of viral transformation|up regulation of transformation of host cell by virus|activation of viral transformation|up-regulation of viral transformation of host cell|up-regulation of viral transformation|upregulation of viral transformation|up regulation of viral transformation							pga	2015-05-05T15:30:11Z					biological_process											owl:Class	
GO:0035735	biolink:NamedThing	intraciliary transport involved in cilium assembly	The bidirectional movement of large protein complexes along microtubules within a cilium that contributes to cilium assembly.	tmpzr1t_l9r_go_relaxed.owl	intraflagellar transport involved in cilium morphogenesis|intraflagellar transport|intraciliary transport involved in cilium morphogenesis				Reactome:R-HSA-5620924.2			bf	2011-03-17T10:55:42Z					biological_process											owl:Class	
GO:0043630	biolink:NamedThing	ncRNA polyadenylation involved in polyadenylation-dependent ncRNA catabolic process	The enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end of a non-coding RNA, occurring as part of the process of polyadenylation-dependent non-coding RNA catabolism.	tmpzr1t_l9r_go_relaxed.owl	ncRNA polyadenylation involved in poly(A)-dependent ncRNA catabolic process|ncRNA polyadenylation during polyadenylation-dependent ncRNA catabolic process													biological_process											owl:Class	
GO:0016531	biolink:NamedThing	copper chaperone activity	Directly binding to and delivering copper ions to a target protein.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0004948	biolink:NamedThing	calcitonin receptor activity	Combining with calcitonin and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1900016	biolink:NamedThing	negative regulation of cytokine production involved in inflammatory response	Any process that stops, prevents or reduces the frequency, rate or extent of cytokine production involved in inflammatory response.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of cytokine production involved in acute inflammatory response|down regulation of cytokine production involved in inflammatory response|down regulation of cytokine production involved in acute inflammatory response							rph	2012-01-11T09:34:31Z					biological_process											owl:Class	
GO:0002534	biolink:NamedThing	cytokine production involved in inflammatory response	The synthesis or release of a cytokine following a inflammatory stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels.	tmpzr1t_l9r_go_relaxed.owl	cytokine production involved in acute inflammatory response													biological_process											owl:Class	
GO:0060550	biolink:NamedThing	positive regulation of fructose 1,6-bisphosphate 1-phosphatase activity	Any process that increases the rate, frequency or extent of fructose 1,6-bisphosphate 1-phosphatase activity. Fructose 1,6-bisphosphate 1-phosphatase activity is the catalysis of the reaction: D-fructose 1,6-bisphosphate + H2O = D-fructose 6-phosphate + phosphate.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-04-13T02:12:33Z					biological_process											owl:Class	
GO:0042132	biolink:NamedThing	fructose 1,6-bisphosphate 1-phosphatase activity	Catalysis of the reaction: D-fructose 1,6-bisphosphate + H2O = D-fructose 6-phosphate + phosphate.	tmpzr1t_l9r_go_relaxed.owl	fructose 1,6-bisphosphate phosphatase activity|D-fructose-1,6-bisphosphate 1-phosphohydrolase activity|fructose bisphosphate phosphatase activity|fructose 1,6-diphosphate phosphatase activity|fructose diphosphate phosphatase activity|fructose 1,6-diphosphatase activity|hexosediphosphatase activity|hexose diphosphatase activity|fructose-bisphosphatase activity|fructose 1,6-bisphosphatase activity|D-fructose-1,6-bisphosphate phosphatase activity|hexose bisphosphatase activity|fructose-1,6-bisphosphatase activity|fructose diphosphatase activity|FBPase activity|D-fructose 1,6-diphosphatase activity				RHEA:11064|MetaCyc:F16BDEPHOS-RXN|EC:3.1.3.11|Reactome:R-HSA-70479									molecular_function											owl:Class	
GO:0070132	biolink:NamedThing	regulation of mitochondrial translational initiation	Any process that modulates the frequency, rate or extent of the process preceding formation of the peptide bond between the first two amino acids of a protein in a mitochondrion.	tmpzr1t_l9r_go_relaxed.owl	regulation of mitochondrial translation initiation													biological_process											owl:Class	
GO:0033282	biolink:NamedThing	protein C inhibitor-acrosin complex	A heterodimeric protein complex of protein C inhibitor (SERPINA5) and acrosin; formation of the complex inhibits the protease activity of acrosin.	tmpzr1t_l9r_go_relaxed.owl	serpin A5-acrosin complex|PCI-acrosin complex|SERPINA5-acrosin complex|plasma serine protease inhibitor-acrosin complex|PCI-ACR complex													cellular_component											owl:Class	
GO:0002328	biolink:NamedThing	pro-B cell differentiation	The process in which a precursor cell type acquires the specialized features of a pro-B cell. Pro-B cells are the earliest stage of the B cell lineage and undergo heavy chain D and J gene rearrangements, although they are not fully committed.	tmpzr1t_l9r_go_relaxed.owl	pro-B lymphocyte differentiation|pro-B cell development													biological_process											owl:Class	
GO:0007054	biolink:NamedThing	spindle assembly involved in male meiosis I	The formation of the spindle during meiosis I of a meiotic cell cycle in males. An example of this is found in Drosophila melanogaster.	tmpzr1t_l9r_go_relaxed.owl	male meiosis I spindle assembly													biological_process											owl:Class	
GO:1905889	biolink:NamedThing	positive regulation of cellular response to very-low-density lipoprotein particle stimulus	Any process that activates or increases the frequency, rate or extent of cellular response to very-low-density lipoprotein particle stimulus.	tmpzr1t_l9r_go_relaxed.owl	activation of cellular response to VLDL particle stimulus|upregulation of cellular response to very-low-density lipoprotein particle stimulus|up-regulation of cellular response to VLDL particle stimulus|up regulation of cellular response to VLDL particle stimulus|activation of cellular response to very-low-density lipoprotein particle stimulus|positive regulation of cellular response to VLDL particle stimulus|upregulation of cellular response to VLDL particle stimulus|up-regulation of cellular response to very-low-density lipoprotein particle stimulus|up regulation of cellular response to very-low-density lipoprotein particle stimulus							bc	2017-02-01T10:09:34Z					biological_process											owl:Class	
GO:0051484	biolink:NamedThing	isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway involved in terpenoid biosynthetic process	The chemical reactions and pathways resulting in the formation of isopentenyl diphosphate by the mevalonate-independent pathway that contributes to terpenoid biosynthesis. Isopentenyl diphosphate (IPP) is the fundamental unit in isoprenoid biosynthesis and is biosynthesized from pyruvate and glyceraldehyde 3-phosphate via intermediates, including 1-deoxy-D-xylulose 5-phosphate.	tmpzr1t_l9r_go_relaxed.owl	isopentenyl diphosphate anabolism, mevalonate-independent pathway, during terpenoid anabolism|isopentenyl diphosphate biosynthetic process, mevalonate-independent pathway involved in terpenoid biosynthetic process|isopentenyl diphosphate formation, mevalonate-independent pathway, during terpenoid biosynthesis|isopentenyl diphosphate synthesis, mevalonate-independent pathway, during terpenoid synthesis|isopentenyl diphosphate biosynthetic process, mevalonate-independent pathway, during terpenoid biosynthetic process|isopentenyl diphosphate formation, mevalonate-independent pathway, during terpenoid formation				MetaCyc:NONMEVIPP-PWY									biological_process											owl:Class	
GO:0051483	biolink:NamedThing	terpenoid biosynthetic process, mevalonate-independent	The chemical reactions and pathways resulting in the formation of terpenoids, independent of mevalonate. Isopentenyl diphosphate (IPP) is the fundamental unit in terpenoid biosynthesis, and in mevalonate-independent biosynthesis, it is produced from pyruvate and glyceraldehyde 3-phosphate via intermediates including 1-deoxy-D-xylulose 5-phosphate.	tmpzr1t_l9r_go_relaxed.owl	mevalonate-independent terpenoid biosynthesis|mevalonate-independent terpene biosynthesis|mevalonate-independent terpene biosynthetic process|terpenoid synthesis, mevalonate-independent|terpene biosynthetic process, mevalonate-independent|mevalonate-independent terpenoid biosynthetic process|terpenoid anabolism, mevalonate-independent|terpenoid formation, mevalonate-independent|terpene biosynthesis, mevalonate-independent													biological_process											owl:Class	
GO:0044331	biolink:NamedThing	cell-cell adhesion mediated by cadherin	The attachment of one cell to another cell via a cadherin, transmembrane proteins having repeating extracellular calcium ion binding domains.	tmpzr1t_l9r_go_relaxed.owl								jl	2010-08-20T10:24:54Z					biological_process											owl:Class	
GO:0034403	biolink:NamedThing	alignment of 3' and 5' splice sites of mRNA	Recognition of both the 5' and 3'-splice sites and positioning them in the correct alignment with respect to each other so that the second catalytic step of nuclear mRNA splicing can occur.	tmpzr1t_l9r_go_relaxed.owl	alignment of 3' and 5' splice sites of nuclear mRNA													biological_process											owl:Class	
GO:0000350	biolink:NamedThing	generation of catalytic spliceosome for second transesterification step	Conformational rearrangement of the spliceosomal complex containing the RNA products from the 1st step of splicing to form the catalytic site for the second step of splicing.	tmpzr1t_l9r_go_relaxed.owl	catalytic spliceosome assembly for second transesterification step|spliceosomal A2-3 complex biosynthesis|formation of catalytic spliceosome for second transesterification step|spliceosomal A2-3 complex formation|spliceosomal C2 complex formation|lariat formation, 5'-splice site cleavage|formation of spliceosomal C1 complex|formation of catalytic U12-type spliceosome for second transesterification step|formation of spliceosomal A2-2 complex|spliceosomal C2 complex biosynthesis|formation of catalytic U2-type spliceosome for second transesterification step					Note that this step represents formation of the A2-3 complex (yeast) or the C2 complex (mammalian).						GO:0000359|GO:0000358		biological_process											owl:Class	
GO:0075243	biolink:NamedThing	oospore formation	The process in which male and female gametangia develop and fuse to form an oospore, a thick-walled resting spore of Oomycetes and certain algae and fungi.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1900045	biolink:NamedThing	negative regulation of protein K63-linked ubiquitination	Any process that stops, prevents or reduces the frequency, rate or extent of protein K63-linked ubiquitination.	tmpzr1t_l9r_go_relaxed.owl	downregulation of protein K63-linked ubiquitination|down regulation of protein K63-linked ubiquitination|downregulation of protein K63-linked polyubiquitination|down-regulation of protein K63-linked ubiquitination|down-regulation of protein K63-linked polyubiquitination|down regulation of protein K63-linked polyubiquitination|negative regulation of protein K63-linked polyubiquitination|inhibition of protein K63-linked ubiquitination|inhibition of protein K63-linked polyubiquitination							bf	2012-01-19T11:44:41Z					biological_process											owl:Class	
GO:0070534	biolink:NamedThing	protein K63-linked ubiquitination	A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 63 of the ubiquitin monomers, is added to a protein. K63-linked ubiquitination does not target the substrate protein for degradation, but is involved in several pathways, notably as a signal to promote error-free DNA postreplication repair.	tmpzr1t_l9r_go_relaxed.owl	protein K63-linked polyubiquitination													biological_process											owl:Class	
GO:0052807	biolink:NamedThing	aflatoxin reductase (coenzyme F420) activity	Catalysis of the reaction: aflatoxin + 1,5-dihydrocoenzyme F420 = aflatoxin with reduced furanocoumarin moiety + coenzyme F420. 1,5-dihydrocoenzyme F420 is also known as reduced coenzyme F420.	tmpzr1t_l9r_go_relaxed.owl	coenzyme F420-aflatoxin reductase activity|aflatoxin:reduced coenzyme F420 reductase activity|coenzyme F420-dependent aflatoxin reductase activity|aflatoxin:coenzyme F420 oxidoreductase activity							ai	2011-09-22T04:08:13Z					molecular_function											owl:Class	
GO:1904531	biolink:NamedThing	positive regulation of actin filament binding	Any process that activates or increases the frequency, rate or extent of actin filament binding.	tmpzr1t_l9r_go_relaxed.owl	upregulation of actin filament binding|activation of actin filament binding|positive regulation of F-actin binding|upregulation of actin cross-linking activity|up regulation of actin cross-linking activity|upregulation of F-actin binding|activation of F-actin binding|up-regulation of F-actin binding|positive regulation of actin cross-linking activity|up-regulation of actin filament binding|up-regulation of actin cross-linking activity|up regulation of F-actin binding|activation of actin cross-linking activity|up regulation of actin filament binding							als	2015-07-30T10:42:01Z					biological_process											owl:Class	
GO:0021693	biolink:NamedThing	cerebellar Purkinje cell layer structural organization	The process that contributes to the act of creating the structural organization of the cerebellar Purkinje cell layer. This process pertains to the physical shaping of a rudimentary structure. The Purkinje cell layer lies just underneath the molecular layer of the cerebellar cortex. It contains the neuronal cell bodies of the Purkinje cells that are arranged side by side in a single layer. Candelabrum interneurons are vertically oriented between the Purkinje cells. Purkinje neurons are inhibitory and provide the output of the cerebellar cortex through axons that project into the white matter. Extensive dendritic trees from the Purkinje cells extend upward in a single plane into the molecular layer where they synapse with parallel fibers of granule cells.	tmpzr1t_l9r_go_relaxed.owl	cerebellar Purkinje cell layer structural organisation													biological_process											owl:Class	
GO:0016174	biolink:NamedThing	NAD(P)H oxidase H2O2-forming activity	Catalysis of the reaction: NAD(P)H + H+ + O2 = NAD(P)+ + hydrogen peroxide.	tmpzr1t_l9r_go_relaxed.owl	NAD(P)H oxidase activity|NAD(P)H:oxygen oxidoreductase activity|thyroid NADPH oxidase activity|thyroid oxidase activity|THOX2 activity|dual oxidase activity|ThOX activity|thyroid oxidase 2 activity|p138tox|NADPH oxidase				Reactome:R-HSA-5693681|Reactome:R-HSA-9698758|EC:1.6.3.1									molecular_function											owl:Class	
GO:1901196	biolink:NamedThing	positive regulation of calcium-mediated signaling involved in cellular response to salt stress	Any positive regulation of calcium-mediated signaling that is involved in cellular response to salt stress.	tmpzr1t_l9r_go_relaxed.owl	stimulation of calcium-mediated signaling involved in cellular response to ionic osmotic stress|upregulation of calcium-mediated signaling involved in cellular salinity response|up-regulation of calcium-mediated signaling involved in cellular response to ionic osmotic stress|activation of calcium-mediated signaling involved in cellular response to salt stress|stimulation of calcium-mediated signaling involved in cellular salinity response|up regulation of calcium-mediated signaling involved in cellular response to salt stress|activation of calcium-mediated signaling involved in cellular salinity response|up-regulation of calcium-mediated signaling involved in cellular salinity response|positive regulation of calcium-mediated signalling involved in cellular response to salt stress|up regulation of calcium-mediated signaling involved in cellular response to ionic osmotic stress|activation of calcium-mediated signaling involved in cellular response to ionic osmotic stress|positive regulation of calcium-mediated signalling involved in cellular salinity response|positive regulation of calcium-mediated signaling involved in cellular salinity response|up regulation of calcium-mediated signaling involved in cellular salinity response|positive regulation of calcium-mediated signalling involved in cellular response to ionic osmotic stress|upregulation of calcium-mediated signaling involved in cellular response to salt stress|upregulation of calcium-mediated signaling involved in cellular response to ionic osmotic stress|up-regulation of calcium-mediated signaling involved in cellular response to salt stress|stimulation of calcium-mediated signaling involved in cellular response to salt stress|positive regulation of calcium-mediated signaling involved in cellular response to ionic osmotic stress							al	2012-07-27T10:52:56Z					biological_process											owl:Class	
GO:0050653	biolink:NamedThing	chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process	The elongation of chondroitin sulfate proteoglycan chains by alternate addition of N-acetylhexosamine and GlcUA residues to the GAG-protein linkage region tetrasaccharide of chondroitin sulfate.	tmpzr1t_l9r_go_relaxed.owl	chondroitin sulfate proteoglycan formation, polysaccharide chain formation|chondroitin sulfate proteoglycan chain elongation|chondroitin sulfate proteoglycan anabolism, polysaccharide chain anabolism|chondroitin sulphate proteoglycan biosynthesis, polysaccharide chain biosynthesis|chondroitin sulphate proteoglycan biosynthesis, polysaccharide chain biosynthetic process|chondroitin sulfate proteoglycan synthesis, polysaccharide chain synthesis|chondroitin sulfate proteoglycan formation, polysaccharide chain biosynthesis													biological_process											owl:Class	
GO:0050650	biolink:NamedThing	chondroitin sulfate proteoglycan biosynthetic process	The chemical reactions and pathways resulting in the formation of chondroitin sulfate proteoglycan, any glycoprotein whose glycosaminoglycan units are chondroitin sulfate. Chondroitin sulfates are a group of 10-60 kDa glycosaminoglycans, widely distributed in cartilage and other mammalian connective tissues; the repeat units consist of beta-(1,4)-linked D-glucuronyl beta-(1,3)-N-acetyl-D-galactosamine sulfate.	tmpzr1t_l9r_go_relaxed.owl	chondroitin sulfate proteoglycan formation|chondroitin sulfate proteoglycan anabolism|chondroitin sulphate proteoglycan biosynthetic process|chondroitin sulfate proteoglycan biosynthesis|chondroitin sulphate proteoglycan biosynthesis|chondroitin sulfate proteoglycan synthesis													biological_process											owl:Class	
GO:0072660	biolink:NamedThing	maintenance of protein location in plasma membrane	Any process in which a protein is maintained in a specific location in the plasma membrane, and is prevented from moving elsewhere.	tmpzr1t_l9r_go_relaxed.owl								mah	2011-02-14T02:46:08Z					biological_process											owl:Class	
GO:0097114	biolink:NamedThing	NMDA glutamate receptor clustering	The receptor clustering process in which N-methyl-D-aspartate (NMDA) receptors are localized to distinct domains in the cell membrane.	tmpzr1t_l9r_go_relaxed.owl	NMDA receptor clustering|N-methyl-D-aspartate receptor clustering							pr	2011-07-31T05:30:15Z					biological_process											owl:Class	
GO:0034170	biolink:NamedThing	toll-like receptor 11 signaling pathway	Any series of molecular signals generated as a consequence of binding to toll-like receptor 11.	tmpzr1t_l9r_go_relaxed.owl	toll-like receptor 11 signalling pathway|TLR11 signaling pathway													biological_process											owl:Class	
GO:0030226	biolink:NamedThing	apolipoprotein receptor activity	Combining with an apolipoprotein to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1905498	biolink:NamedThing	positive regulation of triplex DNA binding	Any process that activates or increases the frequency, rate or extent of triplex DNA binding.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of triplex DNA binding|activation of triplex DNA binding|upregulation of triplex DNA binding|up regulation of triplex DNA binding							ans	2016-09-26T14:57:25Z					biological_process											owl:Class	
GO:0045142	biolink:NamedThing	triplex DNA binding	Binding to a DNA triple helix. The formation of triple helical DNA has been evoked in several cellular processes including transcription, replication, and recombination.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0097049	biolink:NamedThing	motor neuron apoptotic process	Any apoptotic process in a motor neuron, an efferent neuron that passes from the central nervous system or a ganglion toward or to a muscle and conducts an impulse that causes movement.	tmpzr1t_l9r_go_relaxed.owl	motor neuron apoptosis|motoneuron apoptosis							pr	2011-05-04T02:21:43Z					biological_process											owl:Class	
GO:0120183	biolink:NamedThing	positive regulation of focal adhesion disassembly	Any process that activates or increases the frequency, rate or extent of disaggregation of a focal adhesion into its constituent components.	tmpzr1t_l9r_go_relaxed.owl								krc	2018-07-12T18:27:19Z					biological_process											owl:Class	
GO:0097614	biolink:NamedThing	dinoflagellate hypocone	The part of a dinoflagellate cell below the cingulum; also referred to as the posterior portion of a dinoflagellate cell. It is separated from the epicone by the cingulum.	tmpzr1t_l9r_go_relaxed.owl	hypotheca|hyposome|hypocone					The term name refers to a taxonomic group to make the label unique with respect to similarly-named anatomical structures.		pr	2014-06-09T11:35:07Z					cellular_component											owl:Class	
GO:0071051	biolink:NamedThing	polyadenylation-dependent snoRNA 3'-end processing	Any process involved in forming the mature 3' end of a snoRNA molecule linked to prior polyadenylation of the 3'-end of the precursor snoRNA.	tmpzr1t_l9r_go_relaxed.owl	poly(A)-dependent snoRNA 3'-end processing							krc	2009-08-25T03:47:24Z					biological_process											owl:Class	
GO:0021890	biolink:NamedThing	olfactory bulb interneuron fate commitment	The process in which the developmental fate of a neuroblast becomes restricted such that it will develop into an interneuron residing in the olfactory bulb.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0150071	biolink:NamedThing	negative regulation of arginase activity	Any process that stops, prevents or reduces the frequency, rate or extent of arginase activity.	tmpzr1t_l9r_go_relaxed.owl								bc	2018-07-25T09:22:32Z					biological_process											owl:Class	
GO:0016014	biolink:NamedThing	dystrobrevin complex	A protein complex comprising alpha- and beta-dystrobrevin; forms part of the dystrophin glycoprotein complex.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0035448	biolink:NamedThing	extrinsic component of thylakoid membrane	The component of a thylakoid membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.	tmpzr1t_l9r_go_relaxed.owl	peripheral to thylakoid membrane|extrinsic to thylakoid membrane							bf	2010-04-16T10:11:32Z					cellular_component											owl:Class	
GO:0098946	biolink:NamedThing	intrinsic component of presynaptic endocytic zone membrane	The component of the presynaptic endocytic zone membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.	tmpzr1t_l9r_go_relaxed.owl	intrinsic to presynaptic acive zone membrane													cellular_component											owl:Class	
GO:0060734	biolink:NamedThing	regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation	Any process that modulates the rate, frequency, or extent of eIF2 alpha phosphorylation as a cellular response to endoplasmic reticulum stress.	tmpzr1t_l9r_go_relaxed.owl	regulation of eIF2 alpha phosphorylation by ER stress|regulation of ER stress-induced eIF2 alpha phosphorylation|regulation of eIF2 alpha phosphorylation by endoplasmic reticulum stress							dph	2009-06-12T02:15:16Z					biological_process											owl:Class	
GO:1990765	biolink:NamedThing	colon smooth muscle contraction	A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry of the large intestine, exclusive of the rectum. The colon is that part of the large intestine that connects the small intestine to the rectum.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-06-10T18:29:21Z					biological_process											owl:Class	
GO:0046629	biolink:NamedThing	gamma-delta T cell activation	The change in morphology and behavior of a gamma-delta T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.	tmpzr1t_l9r_go_relaxed.owl	gamma-delta T lymphocyte activation|gamma-delta T-cell activation|gamma-delta T-lymphocyte activation													biological_process											owl:Class	
GO:1900437	biolink:NamedThing	regulation of filamentous growth of a population of unicellular organisms in response to chemical stimulus	Any process that modulates the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to chemical stimulus.	tmpzr1t_l9r_go_relaxed.owl								di	2012-04-25T05:55:17Z					biological_process											owl:Class	
GO:0003161	biolink:NamedThing	cardiac conduction system development	The process whose specific outcome is the progression of the cardiac conduction system over time, from its formation to the mature structure. The cardiac conduction system consists of specialized cardiomyocytes that regulate the frequency of heart beat.	tmpzr1t_l9r_go_relaxed.owl	heart conduction system development|cardiac impulse conducting system development							dph	2009-10-01T01:57:16Z					biological_process											owl:Class	
GO:0007510	biolink:NamedThing	cardioblast cell fate determination	The cell fate determination process in which a cell becomes capable of differentiating autonomously into a cardioblast cell regardless of its environment; upon determination, the cell fate cannot be reversed. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0034171	biolink:NamedThing	regulation of toll-like receptor 11 signaling pathway	Any process that modulates the frequency, rate, or extent of toll-like receptor 11 signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	regulation of TLR11 signaling pathway|regulation of toll-like receptor 11 signalling pathway													biological_process											owl:Class	
GO:0030121	biolink:NamedThing	AP-1 adaptor complex	A heterotetrameric AP-type membrane coat adaptor complex that consists of beta1, gamma, mu1 and sigma1 subunits and links clathrin to the membrane surface of a vesicle; vesicles with AP-1-containing coats are normally found primarily in the trans-Golgi network. In at least humans, the AP-1 complex can be heterogeneric due to the existence of multiple subunit isoforms encoded by different genes (gamma1 and gamma2, mu1A and mu1B, and sigma1A, sigma1B and sigma1C).	tmpzr1t_l9r_go_relaxed.owl	AP-1 related adapter complex|HA1 clathrin adaptor|HA1													cellular_component											owl:Class	
GO:0021846	biolink:NamedThing	cell proliferation in forebrain	The creation of greater cell numbers in the forebrain due to cell division of progenitor cells.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0021713	biolink:NamedThing	inferior olivary nucleus development	The process whose specific outcome is the progression of the inferior olivary nucleus over time, from its formation to the mature structure. The inferior olivary nucleus is a capsule-shaped structure in the ventral medulla located just lateral and dorsal to the medullary pyramids. Neurons in the inferior olivary nucleus are the source of climbing fiber input to the cerebellar cortex; these neurons have been implicated in various functions, such as learning and timing of movements.	tmpzr1t_l9r_go_relaxed.owl	inferior olive development													biological_process											owl:Class	
GO:0048689	biolink:NamedThing	formation of growth cone in injured axon	The formation of a growth cone in an injured axon.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0003350	biolink:NamedThing	pulmonary myocardium development	The progression of the pulmonary myocardium over time, from its initial formation to the mature structure. The pulmonary myocardium is the myocardial tissue present in the pulmonary vein.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-12-01T12:50:06Z					biological_process											owl:Class	
GO:0061214	biolink:NamedThing	mesonephric smooth muscle tissue development	The process whose specific outcome is the progression of smooth muscle in the mesonephros over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-08-17T03:29:54Z					biological_process											owl:Class	
GO:0090368	biolink:NamedThing	regulation of ornithine metabolic process	Any process that modulates the rate, frequency, or extent of the chemical reactions and pathways involving ornithine, an amino acid only rarely found in proteins, but which is important in living organisms as an intermediate in the reactions of the urea cycle and in arginine biosynthesis.	tmpzr1t_l9r_go_relaxed.owl								tb	2010-07-12T11:14:12Z					biological_process											owl:Class	
GO:0021808	biolink:NamedThing	cytosolic calcium signaling involved in initiation of cell movement in glial-mediated radial cell migration	The process that results in the fluctuations in intracellular calcium that are responsible for the initiation of movement as a component of the process of cerebral cortex glial-mediated radial migration.	tmpzr1t_l9r_go_relaxed.owl	cytosolic calcium signalling involved in the initiation of cell movement in glial-mediated radial cell migration													biological_process											owl:Class	
GO:0044638	biolink:NamedThing	envenomation resulting in positive regulation of complement activation, classical pathway in other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the positive regulation of complement activation via the classical pathway of the bitten/stung organism.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-07-05T04:51:36Z					biological_process											owl:Class	
GO:0045706	biolink:NamedThing	positive regulation of salivary gland boundary specification	Any process that activates or increases the frequency, rate or extent of salivary gland determination.	tmpzr1t_l9r_go_relaxed.owl	upregulation of salivary gland determination|up-regulation of salivary gland determination|positive regulation of salivary gland determination|activation of salivary gland determination|stimulation of salivary gland determination|up regulation of salivary gland determination													biological_process											owl:Class	
GO:0061353	biolink:NamedThing	BMP signaling pathway involved in Malpighian tubule cell chemotaxis	A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, which contributes to the directed movement of a Malpighian tubule cell toward a stimulus, thereby contributing to the shaping of the tubule.	tmpzr1t_l9r_go_relaxed.owl	bone morphogenic protein receptor signalling pathway involved in Malpighian tubule cell chemotaxis							dph	2010-10-01T12:01:00Z					biological_process											owl:Class	
GO:0061352	biolink:NamedThing	cell chemotaxis involved in Malpighian tubule morphogenesis	The directed movement of the outgrowing Malpighian tubule guided by specific chemical cues/signals. Movement may be towards a guidance cue (positive chemotaxis) or away from it (negative chemotaxis). Guidance contributes to the final positioning of the tubule.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-10-01T11:57:28Z					biological_process											owl:Class	
GO:0035322	biolink:NamedThing	mesenchymal cell migration involved in limb bud formation	The orderly movement of a mesenchymal cell from one site to another that will contribute to the formation of a limb bud.	tmpzr1t_l9r_go_relaxed.owl								bf	2010-02-24T02:05:14Z					biological_process											owl:Class	
GO:0007263	biolink:NamedThing	nitric oxide mediated signal transduction	Any intracellular signal transduction in which the signal is passed on within the cell via nitric oxide (NO). Includes synthesis of nitric oxide, receptors/sensors for nitric oxide (such as soluble guanylyl cyclase/sGC) and downstream effectors that further transmit the signal within the cell. Nitric oxide transmits its downstream effects through either cyclic GMP (cGMP)-dependent or independent mechanisms.	tmpzr1t_l9r_go_relaxed.owl	nitric oxide signaling|NO mediated signal transduction|nitric oxide-mediated signal transduction|NO-mediated signal transduction													biological_process											owl:Class	
GO:0034985	biolink:NamedThing	Ecsit-NDUFAF1 complex	Any large protein complex that contains Ecsit and NDUFAF1, is located in the mitochondrion, and is involved in the assembly of complex I of the oxidative phosphorylation system. In mammalian cells, three complexes of approximately 500, 600, and 850 kDa containing the 45 kDa isoform of Ecsit and NDUFAF1 have been observed.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:2000822	biolink:NamedThing	regulation of behavioral fear response	Any process that modulates the frequency, rate or extent of behavioral fear response.	tmpzr1t_l9r_go_relaxed.owl	regulation of behavioural fear response							rl	2011-07-14T04:50:47Z					biological_process											owl:Class	
GO:1990260	biolink:NamedThing	negative regulation of transcription from RNA polymerase II promoter by transcription factor localization involved in response to DNA damage checkpoint signaling	Any process that stops, prevents, or reduces the frequency, rate or extent of transcription from an RNA polymerase II promoter using a mechanism that involves the localization of a transcription factor and initiated in response to the DNA damage checkpoint signaling.	tmpzr1t_l9r_go_relaxed.owl								al	2014-01-07T17:10:11Z					biological_process											owl:Class	
GO:0014009	biolink:NamedThing	glial cell proliferation	The multiplication or reproduction of glial cells by cell division, resulting in the expansion of their population. Glial cells exist throughout the nervous system, and include Schwann cells, astrocytes, and oligodendrocytes among others.	tmpzr1t_l9r_go_relaxed.owl	glia proliferation													biological_process											owl:Class	
GO:0003984	biolink:NamedThing	acetolactate synthase activity	Catalysis of the reaction: 2 pyruvate = 2-acetolactate + CO2.	tmpzr1t_l9r_go_relaxed.owl	alpha-acetohydroxyacid synthase activity|alpha-acetolactate synthetase activity|acetohydroxy acid synthetase activity|pyruvate:pyruvate acetaldehydetransferase (decarboxylating)|alpha-acetolactate synthase activity|alpha-acetohydroxy acid synthetase activity|acetohydroxyacid synthase activity|acetolactic synthetase activity|acetolactate pyruvate-lyase (carboxylating) activity				RHEA:25249|MetaCyc:ACETOLACTSYN-RXN|EC:2.2.1.6	Note that this function was formerly EC:4.1.3.18.								molecular_function											owl:Class	
GO:0075317	biolink:NamedThing	ascus development	The process that leads to the development of ascus, a sac-like structure produced by fungi of the phylum Ascomycota (sac fungi) in which sexually produced spores (ascospores), usually four or eight in number, are formed.	tmpzr1t_l9r_go_relaxed.owl						Note that ascospores and asci are separate biological structures. The ascus is the structure that contain the ascospores, but the development of the ascus is a different process than the formation of the ascospores themselves; for instance, some mutations affect sporulation without affecting ascus development. For this reason, GO:0030437 ascospore formation and GO:0075317 ascus development are different terms and are not linked.								biological_process											owl:Class	
GO:0043844	biolink:NamedThing	ADP-specific phosphofructokinase activity	Catalysis of the reaction: ADP + D-fructose 6-phosphate = AMP + D-fructose 1,6-bisphosphate.	tmpzr1t_l9r_go_relaxed.owl	ADP:D-fructose-6-phosphate 1-phosphotransferase activity|ADP-Pfk activity|ADP-6-phosphofructokinase activity|ADP-dependent phosphofructokinase activity				EC:2.7.1.146|RHEA:20105									molecular_function											owl:Class	
GO:0075523	biolink:NamedThing	viral translational frameshifting	A process which occurs during viral translation, which involves a translational recoding mechanism called programmed ribosomal frameshifting. This causes the ribosome to alter its reading of the mRNA to an a different open reading frame to produce alternate viral proteins.	tmpzr1t_l9r_go_relaxed.owl	ribosomal frameshifting involved in viral translation				VZ:860	This term is intended to annotate gene products involved in the process of viral translational frameshifting, not viral proteins produced by this translation process.		jl	2011-08-03T02:48:46Z					biological_process											owl:Class	
GO:0033550	biolink:NamedThing	MAP kinase tyrosine phosphatase activity	Catalysis of the reaction: MAP kinase tyrosine phosphate + H2O = MAP kinase tyrosine + phosphate.	tmpzr1t_l9r_go_relaxed.owl	tyrosine-specific MAP kinase phosphatase activity													molecular_function											owl:Class	
GO:0051298	biolink:NamedThing	centrosome duplication	The replication of a centrosome, a structure comprised of a pair of centrioles and peri-centriolar material from which a microtubule spindle apparatus is organized.	tmpzr1t_l9r_go_relaxed.owl	centrosome replication													biological_process											owl:Class	
GO:0031447	biolink:NamedThing	negative regulation of fast-twitch skeletal muscle fiber contraction	Any process that stops, prevents, or reduces the frequency, rate or extent of fast-twitch skeletal muscle contraction.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of fast-twitch skeletal muscle contraction|down regulation of fast-twitch skeletal muscle contraction|down-regulation of fast-twitch skeletal muscle contraction|inhibition of fast-twitch skeletal muscle contraction|downregulation of fast-twitch skeletal muscle contraction													biological_process											owl:Class	
GO:0033008	biolink:NamedThing	positive regulation of mast cell activation involved in immune response	Any process that activates or increases the frequency, rate, or extent of mast cell activation as part of an immune response.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of mast cell activation during immune response													biological_process											owl:Class	
GO:0003135	biolink:NamedThing	fibroblast growth factor receptor signaling pathway involved in heart induction	The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands that contributes to heart induction.	tmpzr1t_l9r_go_relaxed.owl	fibroblast growth factor receptor signalling pathway involved in heart induction							tb	2009-09-22T03:17:49Z					biological_process											owl:Class	
GO:0010058	biolink:NamedThing	regulation of atrichoblast fate specification	Any process that modulates atrichoblast fate specification.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0047146	biolink:NamedThing	sterigmatocystin 7-O-methyltransferase activity	Catalysis of the reaction: sterigmatocystin + S-adenosyl-L-methionine = 7-O-methylsterigmatocystin + S-adenosyl-homocysteine.	tmpzr1t_l9r_go_relaxed.owl	S-adenosyl-L-methionine:sterigmatocystin 7-O-methyltransferase activity|O-methyltransferase II activity|sterigmatocystin methyltransferase activity|sterigmatocystin 8-O-methyltransferase activity|S-adenosyl-L-methionine:sterigmatocystin 8-O-methyltransferase activity				RHEA:15561|EC:2.1.1.110|MetaCyc:2.1.1.110-RXN									molecular_function											owl:Class	
GO:0060764	biolink:NamedThing	cell-cell signaling involved in mammary gland development	Any process that mediates the transfer of information from one cell to another and contributes to the progression of the mammary gland, from its initial state to the mature structure.	tmpzr1t_l9r_go_relaxed.owl	cell-cell signalling involved in mammary gland development							dph	2009-07-06T09:24:53Z					biological_process											owl:Class	
GO:0002078	biolink:NamedThing	membrane fusion involved in acrosome reaction	The fusion of the plasma membrane of the sperm with the outer acrosomal membrane.	tmpzr1t_l9r_go_relaxed.owl	membrane fusion involved in the acrosomal reaction													biological_process											owl:Class	
GO:0001551	biolink:NamedThing	ovarian follicle endowment	Association of oocytes with supporting epithelial granulosa cells to form primordial follicles.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0022013	biolink:NamedThing	pallium cell proliferation in forebrain	The multiplication or reproduction of pallium cells in the forebrain, resulting in the expansion of the cell population.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0090367	biolink:NamedThing	negative regulation of mRNA modification	Any process that decreases the rate, frequency, or extent of the covalent alteration of one or more nucleotides within an mRNA molecule to produce an mRNA molecule with a sequence that differs from that coded genetically.	tmpzr1t_l9r_go_relaxed.owl								tb	2010-07-12T11:04:45Z					biological_process											owl:Class	
GO:1904269	biolink:NamedThing	cell leading edge cell cortex	The cell cortex of the leading edge of a cell.	tmpzr1t_l9r_go_relaxed.owl	cell periphery of front of cell|peripheral cytoplasm of leading edge of cell|peripheral cytoplasm of cell leading edge|cell cortex of leading edge of cell|cell periphery of leading edge of cell|cell periphery of cell leading edge|peripheral cytoplasm of front of cell|cell cortex of cell leading edge|cell cortex of front of cell							kmv	2015-05-28T19:16:03Z					cellular_component											owl:Class	
GO:0001560	biolink:NamedThing	regulation of cell growth by extracellular stimulus	Any process in which external signals modulate the frequency, rate or extent of cell growth, the irreversible increase in size of a cell over time.	tmpzr1t_l9r_go_relaxed.owl	regulation of growth by exogenous stimulus|interpretation of external signals that regulate cell growth|regulation of growth by exogenous signal|regulation of cell growth by sensing of exogenous stimulus|regulation of growth by external stimuli|regulation of growth by external stimulus|regulation of growth by external signal|regulation of cell growth by detection of exogenous stimulus|regulation of growth by exogenous stimuli													biological_process											owl:Class	
GO:0044131	biolink:NamedThing	negative regulation of development of symbiont in host	Any process in which the symbiont stops, prevents or reduces its progression from an initial condition to a later condition, within the cells or tissues of the host organism. The host is defined as the larger of the organisms involved in the symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl						This term partially replaces the obsolete term 'negative regulation of growth or development of symbiont in host ; GO:0033667'. See also 'negative regulation of growth of symbiont in host ; GO:0044130'.		jl	2009-08-04T02:42:56Z					biological_process											owl:Class	
GO:0020018	biolink:NamedThing	ciliary pocket membrane	That part of the plasma membrane found in the ciliary pocket (also called flagellar pocket).	tmpzr1t_l9r_go_relaxed.owl	cilium pocket membrane|cilial pocket membrane|flagellar pocket membrane					Note that cilia and eukaryotic flagella are deemed to be equivalent. In this case community usage is mostly 'flagellar', but the primary term name reflects the cilium parentage.								cellular_component											owl:Class	
GO:0020022	biolink:NamedThing	acidocalcisome	An electron-dense acidic membrane-bounded organelle which contains a matrix of pyrophosphate and polyphosphates with bound calcium and other cations.	tmpzr1t_l9r_go_relaxed.owl	metachromatic granule|polyphosphate vacuole|volutin granule													cellular_component											owl:Class	
GO:0043245	biolink:NamedThing	extraorganismal space	The environmental space outside of an organism; this may be a host organism in the case of parasitic and symbiotic organisms.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0070660	biolink:NamedThing	inner ear receptor cell differentiation involved in inner ear sensory epithelium regeneration	Differentiation of new inner ear sensory hair cells to replace those lost or destroyed by injury.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-05-28T04:24:23Z					biological_process											owl:Class	
GO:0070659	biolink:NamedThing	inner ear sensory epithelium regeneration	The regrowth of lost or destroyed inner ear sensory epithelia.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-05-28T04:21:09Z					biological_process											owl:Class	
GO:0033120	biolink:NamedThing	positive regulation of RNA splicing	Any process that activates or increases the frequency, rate or extent of RNA splicing.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0071694	biolink:NamedThing	maintenance of protein location in extracellular region	Any process in which a protein is maintained in a specific location within the extracellular region and is prevented from moving elsewhere.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-02-25T04:04:41Z					biological_process											owl:Class	
GO:0071692	biolink:NamedThing	protein localization to extracellular region	Any process in which a protein is transported from one specific location in the extracellular region to another, or maintained in a specific extracellular location.	tmpzr1t_l9r_go_relaxed.owl	protein localisation in extracellular region|protein localization in extracellular region							mah	2010-02-25T04:00:13Z					biological_process											owl:Class	
GO:0033253	biolink:NamedThing	regulation of penicillinase activity	Any process that modulates the frequency, rate or extent of nuclease activity, the hydrolysis of a penicillin to yield a substituted beta-amino acid derivative.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0033250	biolink:NamedThing	penicillinase activity	Catalysis of the reaction: a penicillin + H2O = a substituted beta-amino acid derivative of the penicillin.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:BETA-LACTAMASE-RXN									molecular_function											owl:Class	
GO:0019779	biolink:NamedThing	Atg8 activating enzyme activity	Catalysis of the activation of the small ubiquitin-related modifier APG8, through the formation of an ATP-dependent high-energy thiolester bond.	tmpzr1t_l9r_go_relaxed.owl	APG8 activating enzyme activity|APG7													molecular_function											owl:Class	
GO:1903220	biolink:NamedThing	positive regulation of malate dehydrogenase (decarboxylating) (NADP+) activity	Any process that activates or increases the frequency, rate or extent of malate dehydrogenase (decarboxylating) (NADP+) activity.	tmpzr1t_l9r_go_relaxed.owl	activation of malate dehydrogenase (NADP, decarboxylating)|activation of NADP-linked decarboxylating malic enzyme|up regulation of NADP-malic enzyme activity|positive regulation of NADP-specific malic enzyme|upregulation of L-malate:NADP oxidoreductase activity|up regulation of NADP-specific malate dehydrogenase activity|up regulation of malate dehydrogenase (NADP, decarboxylating)|upregulation of malate dehydrogenase (decarboxylating) (NADP+) activity|up-regulation of malate dehydrogenase (NADP, decarboxylating)|up-regulation of malate dehydrogenase (decarboxylating, NADP)|up-regulation of NADP-malic enzyme activity|activation of L-malate:NADP oxidoreductase activity|upregulation of malate dehydrogenase (decarboxylating, NADP)|up regulation of malate dehydrogenase (decarboxylating) (NADP+) activity|upregulation of (S)-malate:NADP+ oxidoreductase (oxaloacetate-decarboxylating)|activation of NADP-malic enzyme activity|up regulation of malate dehydrogenase (decarboxylating, NADP)|positive regulation of malate dehydrogenase (NADP, decarboxylating)|positive regulation of 'malic' enzyme|positive regulation of NADP-malic enzyme activity|positive regulation of malate dehydrogenase (decarboxylating, NADP)|up regulation of NADP-specific malic enzyme|up-regulation of NADP-specific malate dehydrogenase activity|upregulation of NADP-malic enzyme activity|up-regulation of NADP-specific malic enzyme|positive regulation of NADP-specific malate dehydrogenase activity|upregulation of 'malic' enzyme|up regulation of 'malic' enzyme|activation of malate dehydrogenase (decarboxylating, NADP)|up regulation of L-malate:NADP oxidoreductase activity|up regulation of NADP-linked decarboxylating malic enzyme|positive regulation of (S)-malate:NADP+ oxidoreductase (oxaloacetate-decarboxylating)|activation of malate dehydrogenase (decarboxylating) (NADP+) activity|activation of NADP-specific malate dehydrogenase activity|up-regulation of (S)-malate:NADP+ oxidoreductase (oxaloacetate-decarboxylating)|activation of 'malic' enzyme|upregulation of NADP-specific malic enzyme|upregulation of NADP-linked decarboxylating malic enzyme|up-regulation of NADP-linked decarboxylating malic enzyme|activation of (S)-malate:NADP+ oxidoreductase (oxaloacetate-decarboxylating)|positive regulation of NADP-linked decarboxylating malic enzyme|upregulation of NADP-specific malate dehydrogenase activity|up-regulation of 'malic' enzyme|activation of NADP-specific malic enzyme|upregulation of malate dehydrogenase (NADP, decarboxylating)|up regulation of (S)-malate:NADP+ oxidoreductase (oxaloacetate-decarboxylating)|positive regulation of L-malate:NADP oxidoreductase activity|up-regulation of malate dehydrogenase (decarboxylating) (NADP+) activity|up-regulation of L-malate:NADP oxidoreductase activity							sart	2014-07-24T11:17:34Z					biological_process											owl:Class	
GO:0070753	biolink:NamedThing	interleukin-35 production	The appearance of interleukin-35 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	tmpzr1t_l9r_go_relaxed.owl	interleukin-35 biosynthetic process|IL-35 production|interleukin-35 secretion							mah	2009-06-23T01:25:11Z			GO:0072626|GO:0070749		biological_process											owl:Class	
GO:0061067	biolink:NamedThing	negative regulation of dauer larval development	Any process that decreases the rate, frequency, or extent of dauer larval development, the process whose specific outcome is the progression of the dauer larva over time, through the facultative diapause of the dauer (enduring) larval stage, with specialized traits adapted for dispersal and long-term survival, with elevated stress resistance and without feeding.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-03-11T01:10:23Z					biological_process											owl:Class	
GO:0010662	biolink:NamedThing	regulation of striated muscle cell apoptotic process	Any process that modulates the rate or extent of striated muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a striated muscle cell and result in its death.	tmpzr1t_l9r_go_relaxed.owl	regulation of striated muscle cell apoptosis													biological_process											owl:Class	
GO:0002655	biolink:NamedThing	regulation of tolerance induction to nonself antigen	Any process that modulates the frequency, rate, or extent of tolerance induction to nonself antigen.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0007419	biolink:NamedThing	ventral cord development	The process whose specific outcome is the progression of the ventral cord over time, from its formation to the mature structure. The ventral cord is one of the distinguishing traits of the central nervous system of all arthropods (such as insects, crustaceans and arachnids) as well as many other invertebrates, such as the annelid worms.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0021897	biolink:NamedThing	forebrain astrocyte development	The process aimed at the progression of an astrocyte that resides in the forebrain, from initial commitment of the cell to its fate, to the fully functional differentiated cell. An astrocyte is the most abundant type of glial cell. Astrocytes provide support for neurons and regulate the environment in which they function.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0097503	biolink:NamedThing	sialylation	The covalent attachment of sialic acid to a substrate molecule.	tmpzr1t_l9r_go_relaxed.owl								pr	2013-09-20T09:53:10Z					biological_process											owl:Class	
GO:0001648	biolink:NamedThing	proteinase activated receptor activity	A G protein-coupled peptide receptor activity that is initiated by cleavage of the N terminus of the receptor by a serine protease, resulting in the generation of a new tethered ligand that interacts with the receptor.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0003140	biolink:NamedThing	determination of left/right asymmetry in lateral mesoderm	The establishment of the lateral mesoderm with respect to the left and right halves.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-09-22T03:58:29Z					biological_process											owl:Class	
GO:2000103	biolink:NamedThing	positive regulation of mammary stem cell proliferation	Any process that activates or increases the frequency, rate or extent of mammary stem cell proliferation.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-09-14T06:10:36Z					biological_process											owl:Class	
GO:0055120	biolink:NamedThing	striated muscle dense body	A vinculin-containing myofibril attachment structure of striated muscle that connects sarcomeres to the extracellular matrix. In nematode body wall muscle, the dense body performs the dual role of Z-disk and costamere.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0014740	biolink:NamedThing	negative regulation of muscle hyperplasia	Any process that stops, prevents, or reduces the frequency, rate, or extent of muscle hyperplasia.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0014900	biolink:NamedThing	muscle hyperplasia	A muscle system process that results in an increase in cell number by cell division, often leading to an increase in the size of an organ.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0030694	biolink:NamedThing	bacterial-type flagellum basal body, rod	The central portion of the bacterial-type flagellar basal body, which spans the periplasm and threads through the rings.	tmpzr1t_l9r_go_relaxed.owl	flagellin-based flagellum basal body, rod|flagellar basal body, rod													cellular_component											owl:Class	
GO:1904341	biolink:NamedThing	regulation of colon smooth muscle contraction	Any process that modulates the frequency, rate or extent of colon smooth muscle contraction.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-06-11T21:16:58Z					biological_process											owl:Class	
GO:0000727	biolink:NamedThing	double-strand break repair via break-induced replication	The error-free repair of a double-strand break in DNA in which the centromere-proximal end of a broken chromosome searches for a homologous region in an intact chromosome. DNA synthesis initiates from the 3' end of the invading DNA strand, using the intact chromosome as the template, and progresses to the end of the chromosome.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0004479	biolink:NamedThing	methionyl-tRNA formyltransferase activity	Catalysis of the reaction: 10-formyltetrahydrofolate + L-methionyl-tRNA + H2O = tetrahydrofolate + N-formylmethionyl-tRNA.	tmpzr1t_l9r_go_relaxed.owl	10-formyltetrahydrofolate:L-methionyl-tRNA N-formyltransferase activity|methionyl-tRNA transformylase activity|methionyl-transfer RNA transformylase activity|conversion of mitochondrial met-tRNAf to fmet-tRNA|N(10)-formyltetrahydrofolic-methionyl-transfer ribonucleic transformylase activity|methionyl-tRNA Met formyltransferase activity|N10-formyltetrahydrofolic-methionyl-transfer ribonucleic transformylase activity|conversion of met-tRNAf to fmet-tRNA|mitochondrial N-terminal peptidyl-methionine N-formylation|methionyl-transfer ribonucleic transformylase activity|methionyl-transfer ribonucleate methyltransferase activity|methionyl ribonucleic formyltransferase activity|formylmethionyl-transfer ribonucleic synthetase activity|N-terminal peptidyl-methionine N-formylation				EC:2.1.2.9|Reactome:R-HSA-5389841|MetaCyc:METHIONYL-TRNA-FORMYLTRANSFERASE-RXN|RHEA:24380							GO:0070128|GO:0001718		molecular_function											owl:Class	
GO:0071951	biolink:NamedThing	conversion of methionyl-tRNA to N-formyl-methionyl-tRNA	The modification process that results in the conversion of methionine charged on a tRNA(fMet) to N-formyl-methionine-tRNA(fMet).	tmpzr1t_l9r_go_relaxed.owl								mah	2010-10-08T11:54:38Z					biological_process											owl:Class	
GO:0044250	biolink:NamedThing	negative regulation of metabolic activity involved in hibernation	The slowing of metabolic processes to very low levels in order to conserve energy as a part of hibernation.	tmpzr1t_l9r_go_relaxed.owl	inhibition of metabolic activity during hibernation|down-regulation of metabolic activity during hibernation|downregulation of metabolic activity during hibernation|negative regulation of metabolic activity during hibernation|down regulation of metabolic activity during hibernation													biological_process											owl:Class	
GO:0042750	biolink:NamedThing	hibernation	Any process in which an organism enters and maintains a period of dormancy in which to pass the winter. It is characterized by narcosis and by sharp reduction in body temperature and metabolic activity and by a depression of vital signs.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Hibernation									biological_process											owl:Class	
GO:0015228	biolink:NamedThing	coenzyme A transmembrane transporter activity	Enables the transfer of coenzyme A from one side of a membrane to the other. Coenzyme A, 3'-phosphoadenosine-(5')diphospho(4')pantatheine, is an acyl carrier in many acylation and acyl-transfer reactions in which the intermediate is a thiol ester.	tmpzr1t_l9r_go_relaxed.owl	coenzyme A transporter activity													molecular_function											owl:Class	
GO:0021843	biolink:NamedThing	substrate-independent telencephalic tangential interneuron migration	The directional movement of tangentially migrating interneurons that are not guided by attaching to extracellular substrates.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0061194	biolink:NamedThing	taste bud morphogenesis	The process in which the anatomical structures of the taste bud are generated and organized. The taste bud is a specialized area of the tongue that contains taste receptors.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-07-27T11:01:31Z					biological_process											owl:Class	
GO:0023030	biolink:NamedThing	MHC class Ib protein binding, via antigen binding groove	Binding to a major histocompatibility complex class Ib molecules via the antigen binding groove.	tmpzr1t_l9r_go_relaxed.owl									2010-02-16T09:30:50Z					molecular_function											owl:Class	
GO:0023025	biolink:NamedThing	MHC class Ib protein complex binding	Binding to a class Ib major histocompatibility complex.	tmpzr1t_l9r_go_relaxed.owl									2010-02-16T09:30:50Z					molecular_function											owl:Class	
GO:0003371	biolink:NamedThing	establishment or maintenance of cytoskeleton polarity involved in ameboidal cell migration	Any cellular process that results in the specification, formation or maintenance of polarized cytoskeletal structures that contribute to the cell polarity of a migrating ameboid cell.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-12-08T05:42:46Z					biological_process											owl:Class	
GO:0032585	biolink:NamedThing	multivesicular body membrane	The lipid bilayer surrounding a multivesicular body.	tmpzr1t_l9r_go_relaxed.owl	MVB membrane|multivesicular endosome membrane|MVE membrane													cellular_component											owl:Class	
GO:2001134	biolink:NamedThing	methane biosynthetic process from carbon monoxide	The chemical reactions and pathways resulting in the formation of a methane from a carbon monoxide.	tmpzr1t_l9r_go_relaxed.owl								jl	2011-10-13T12:36:20Z					biological_process											owl:Class	
GO:0060084	biolink:NamedThing	synaptic transmission involved in micturition	The process of communication from a neuron to a smooth muscle in the bladder that contributes to the expulsion of urine from the body.	tmpzr1t_l9r_go_relaxed.owl	synaptic transmission involved in urination													biological_process											owl:Class	
GO:0048372	biolink:NamedThing	lateral mesodermal cell fate commitment	The process in which a cell becomes committed to become a lateral mesoderm cell.	tmpzr1t_l9r_go_relaxed.owl	lateral plate mesoderm cell fate commitment|lateral mesoderm cell fate commitment|lateral plate mesodermal cell fate commitment													biological_process											owl:Class	
GO:1904925	biolink:NamedThing	positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization	Any process that activates or increases the frequency, rate or extent of autophagy of the mitochondrion in response to mitochondrial depolarization.	tmpzr1t_l9r_go_relaxed.owl	up regulation of mitophagy in response to mitochondrial depolarization|upregulation of mitophagy in response to mitochondrial depolarization|up-regulation of mitophagy in response to mitochondrial depolarization|activation of mitophagy in response to mitochondrial depolarization							pad	2016-01-26T11:24:05Z					biological_process											owl:Class	
GO:0044326	biolink:NamedThing	dendritic spine neck	Part of the dendritic spine that connects the dendritic shaft to the head of the dendritic spine.	tmpzr1t_l9r_go_relaxed.owl	pedicle|spine neck|neck				NIF_Subcellular:sao1642908940			jl	2010-08-18T02:31:15Z					cellular_component											owl:Class	
GO:0036517	biolink:NamedThing	chemoattraction of serotonergic neuron axon	The process in which a serotonergic neuron growth cone is directed to a specific target site in response to an attractive chemical signal.	tmpzr1t_l9r_go_relaxed.owl	chemoattraction of 5-HT axon|chemoattraction of serotonergic axon							bf	2015-12-17T11:26:03Z					biological_process											owl:Class	
GO:0061592	biolink:NamedThing	phosphatidylserine exposure on osteoblast involved in bone mineralization	A phospholipid scrambling process that results in the appearance of phosphatidylserine on the surface of osteoblasts, and contributes to bone mineralization.	tmpzr1t_l9r_go_relaxed.owl								dph	2014-02-05T15:27:39Z					biological_process											owl:Class	
GO:0010756	biolink:NamedThing	positive regulation of plasminogen activation	Any process that increases the rate, frequency or extent of plasminogen activation. Plasminogen activation is the process in which plasminogen is processed to plasmin.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0110145	biolink:NamedThing	magnetosome lumen	The volume enclosed by the membrane of a magnetosome.	tmpzr1t_l9r_go_relaxed.owl								kmv	2019-05-30T17:42:14Z					cellular_component											owl:Class	
GO:0048369	biolink:NamedThing	lateral mesoderm morphogenesis	The process in which the anatomical structures of the lateral mesoderm are generated and organized.	tmpzr1t_l9r_go_relaxed.owl	lateral plate mesoderm morphogenesis													biological_process											owl:Class	
GO:1902464	biolink:NamedThing	regulation of histone H3-K27 trimethylation	Any process that modulates the frequency, rate or extent of histone H3-K27 trimethylation.	tmpzr1t_l9r_go_relaxed.owl								krc	2013-10-22T14:58:55Z					biological_process											owl:Class	
GO:0098532	biolink:NamedThing	histone H3-K27 trimethylation	The modification of histone H3 by addition of three methyl groups to lysine at position 27 of the histone.	tmpzr1t_l9r_go_relaxed.owl								dos	2013-10-18T14:11:17Z					biological_process											owl:Class	
GO:0050916	biolink:NamedThing	sensory perception of sweet taste	The series of events required to receive a sweet taste stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.	tmpzr1t_l9r_go_relaxed.owl	sweet taste perception													biological_process											owl:Class	
GO:0005011	biolink:NamedThing	macrophage colony-stimulating factor receptor activity	Combining with macrophage colony-stimulating factor (M-CSF) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: ATP + a protein-L-tyrosine = ADP + a protein-L-tyrosine phosphate.	tmpzr1t_l9r_go_relaxed.owl	macrophage colony stimulating factor receptor activity|CSF-1|M-CSF receptor activity|Fms													molecular_function											owl:Class	
GO:0031259	biolink:NamedThing	uropod membrane	The portion of the plasma membrane surrounding a uropod.	tmpzr1t_l9r_go_relaxed.owl	uropodium membrane													cellular_component											owl:Class	
GO:0198738	biolink:NamedThing	cell-cell signaling by wnt	Any process that mediates the transfer of information from one cell to another, medaited by a wnt family protein ligand. This process includes wnt signal transduction in the receiving cell, release of wnt ligand from a secreting cell as well as any processes that actively facilitate wnt transport and presentation to receptor on the recieving cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1900504	biolink:NamedThing	negative regulation of cellulosome assembly	Any process that stops, prevents or reduces the frequency, rate or extent of cellulosome assembly.	tmpzr1t_l9r_go_relaxed.owl	down regulation of cellulosome assembly|inhibition of cellulosome assembly|down-regulation of cellulosome assembly|downregulation of cellulosome assembly							tt	2012-05-02T03:58:26Z					biological_process											owl:Class	
GO:0019684	biolink:NamedThing	photosynthesis, light reaction	The light reactions of photosynthesis, which take place in photosystems II and I. Light energy is harvested and used to power the transfer of electrons among a series of electron donors and acceptors. The final electron acceptor is NADP+, which is reduced to NADPH. NADPH generated from light reactions is used in sugar synthesis in dark reactions. Light reactions also generate a proton motive force across the thylakoid membrane, and the proton gradient is used to synthesize ATP. There are two chemical reactions involved in the light reactions: water oxidation in photosystem II, and NADP reduction in photosystem I.	tmpzr1t_l9r_go_relaxed.owl	photolysis				Wikipedia:Photolysis#Photolysis_in_photosynthesis|MetaCyc:PWY-101									biological_process											owl:Class	
GO:0099581	biolink:NamedThing	ATPase coupled ion transmembrane transporter activity involved in regulation of postsynaptic membrane potential	Any ATPase coupled ion transmembrane transporter activity, occurring in the postsynaptic membrane, that is involved in regulation of postsynaptic membrane potential.	tmpzr1t_l9r_go_relaxed.owl	ATPase-coupled ion transmembrane transporter activity involved in regulation of postsynaptic membrane potential|ATPase coupled ion transmembrane transporter activity involved in regulation of post-synaptic membrane potential													molecular_function											owl:Class	
GO:1904122	biolink:NamedThing	positive regulation of fatty acid beta-oxidation by octopamine signaling pathway	An octopamine signaling pathway that results in positive regulation of fatty acid beta-oxidation.	tmpzr1t_l9r_go_relaxed.owl	up regulation of fatty acid beta-oxidation by octopamine signaling pathway|stimulation of fatty acid beta-oxidation by octopamine signaling pathway|activation of fatty acid beta-oxidation by octopamine signaling pathway|up-regulation of fatty acid beta-oxidation by octopamine signaling pathway|upregulation of fatty acid beta-oxidation by octopamine signaling pathway							kmv	2015-04-08T21:03:13Z					biological_process											owl:Class	
GO:0070757	biolink:NamedThing	interleukin-35-mediated signaling pathway	A series of molecular signals initiated by the binding of interleukin-35 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.	tmpzr1t_l9r_go_relaxed.owl	IL-35-mediated signaling pathway|interleukin-35-mediated signalling pathway							mah	2009-06-23T01:55:02Z					biological_process											owl:Class	
GO:0034745	biolink:NamedThing	APC-IQGAP1-Rac1 complex	A protein complex that contains the tumor suppressor protein adenomatous polyposis coli (APC), the small GTPase Rac1, and the Rac1 and Cdc42 effector IQGAP1; may play a role in cytoskeleton organization and cell migration.	tmpzr1t_l9r_go_relaxed.owl						Note that the gene/protein name 'APC' should not be confused with the abbreviation for 'anaphase promoting complex'.								cellular_component											owl:Class	
GO:0044741	biolink:NamedThing	envenomation resulting in negative regulation of sensory perception of pain in other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the inhibition of the sensory perception of pain in the bitten organism.	tmpzr1t_l9r_go_relaxed.owl	envenomation resulting in inhibition of sensory perception of pain in other organism							jl	2012-11-07T14:02:14Z					biological_process											owl:Class	
GO:1903127	biolink:NamedThing	positive regulation of centriole-centriole cohesion	Any process that activates or increases the frequency, rate or extent of centriole-centriole cohesion.	tmpzr1t_l9r_go_relaxed.owl	up regulation of centriole-centriole cohesion|activation of centriole-centriole cohesion|upregulation of centriole-centriole cohesion|up-regulation of centriole-centriole cohesion							als	2014-06-24T09:31:51Z					biological_process											owl:Class	
GO:0007441	biolink:NamedThing	anterior midgut (ectodermal) morphogenesis	The process in which the anatomical structures of the anterior midgut (ectodermal) are generated and organized.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0072065	biolink:NamedThing	long descending thin limb bend development	The process whose specific outcome is the progression of the long descending thin limb bend over time, from its formation to the mature structure. The long descending thin limb bend is a part of the descending thin limb of a long nephron that lies beyond the prebend segment.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-01-25T04:13:38Z					biological_process											owl:Class	
GO:0009866	biolink:NamedThing	induced systemic resistance, ethylene mediated signaling pathway	The series of molecular signals mediated by ethylene (ethene) involved in induced systemic resistance.	tmpzr1t_l9r_go_relaxed.owl	induced systemic resistance, ethylene mediated signalling pathway|ethene mediated signaling pathway (induced systemic resistance)|induced systemic resistance, ethene mediated signalling pathway|induced systemic resistance, ethene mediated signaling pathway|ethylene mediated signaling pathway (induced systemic resistance)													biological_process											owl:Class	
GO:0048460	biolink:NamedThing	flower formation	The process that gives rise to the flower. This process pertains to the initial formation of a structure from unspecified parts.	tmpzr1t_l9r_go_relaxed.owl												GO:0048410		biological_process											owl:Class	
GO:0071516	biolink:NamedThing	establishment of imprinting at mating-type locus	The initial formation of a stable single-strand DNA lesion that triggers programmed gene conversion at the mating-type locus, thereby restricting mating-type interconversion to one of the two sister chromatids during DNA replication.	tmpzr1t_l9r_go_relaxed.owl	mating type determination, establishment of imprinting							mah	2010-01-06T01:16:27Z					biological_process											owl:Class	
GO:0003026	biolink:NamedThing	regulation of systemic arterial blood pressure by aortic arch baroreceptor feedback	The process that modulates blood pressure by sensing the amount of stretch occurring in the aorta and responding to the input via central nervous system control.	tmpzr1t_l9r_go_relaxed.owl	aortic arch baroreceptor control of systemic arterial blood pressure													biological_process											owl:Class	
GO:0004969	biolink:NamedThing	histamine receptor activity	Combining with histamine to initiate a change in cell activity. Histamine is a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0051381	biolink:NamedThing	histamine binding	Binding to histamine, a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0044022	biolink:NamedThing	histone kinase activity (H3-S28 specific)	Catalysis of the transfer of a phosphate group to the serine-28 residue of the N-terminal tail of histone H3.	tmpzr1t_l9r_go_relaxed.owl	histone serine kinase activity (H3-S28 specific)|histone-serine kinase activity (H3-S28 specific)													molecular_function											owl:Class	
GO:0043988	biolink:NamedThing	histone H3-S28 phosphorylation	The modification of histone H3 by the addition of an phosphate group to a serine residue at position 28 of the histone.	tmpzr1t_l9r_go_relaxed.owl	histone H3S28 phosphorylation|histone H3 phosphorylation at S28													biological_process											owl:Class	
GO:0071809	biolink:NamedThing	regulation of fever generation by regulation of prostaglandin biosynthesis	Any process that modulates the rate or extent of fever generation via regulation of the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of prostaglandin.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-09-03T05:07:17Z					biological_process											owl:Class	
GO:0051356	biolink:NamedThing	visual perception involved in equilibrioception	The series of events during equilibrioception required for an organism to receive a visual stimulus, convert it to a molecular signal, and recognize and characterize the signal. Visual input plays an important role in the ability of an organism to perceive its orientation with respect to gravity.	tmpzr1t_l9r_go_relaxed.owl	visual perception during equilibrioception|perception of orientation with respect to gravity by visual perception|equilibrioception by visual perception													biological_process											owl:Class	
GO:0003295	biolink:NamedThing	cell proliferation involved in atrial ventricular junction remodeling	The multiplication or reproduction of cells that contributes to the reorganization of tissue resulting in the maturation of the atrial ventricular junction.	tmpzr1t_l9r_go_relaxed.owl	cell proliferation involved in atrioventricular junction remodeling|cell proliferation involved in atrio-ventricular junction remodeling							dph	2009-10-22T08:38:30Z					biological_process											owl:Class	
GO:0046836	biolink:NamedThing	glycolipid transport	The directed movement of glycolipids, compounds containing (usually) 1-4 linked monosaccharide residues joined by a glycosyl linkage to a lipid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0061682	biolink:NamedThing	seminal vesicle morphogenesis	The process in which the anatomical structures of a seminal vesicle are generated and organized.	tmpzr1t_l9r_go_relaxed.owl								dph	2015-03-04T13:33:49Z					biological_process											owl:Class	
GO:0097546	biolink:NamedThing	ciliary base	Area of the cilium (also called flagellum) where the basal body and the axoneme are anchored to the plasma membrane. The ciliary base encompasses the distal part of the basal body, transition fibers and transition zone and is structurally and functionally very distinct from the rest of the cilium. In this area proteins are sorted and filtered before entering the cilium, and many ciliary proteins localize specifically to this area.	tmpzr1t_l9r_go_relaxed.owl	cilial base|flagellar base|cilium base|flagellum base					Due to resolution issues, researchers are often unable to assign protein localization to more specific ciliary compartments such as the basal body, transition fibers or transition zone, and instead refer to 'ciliary base'. The terms GO:0036064 'ciliary basal body', GO:0097539 'ciliary transition fiber' and GO:0035869 'ciliary transition zone' represent strictly defined compartments at the ciliary base and should be used for annotation whenever possible. Also, note that cilia and eukaryotic flagella are deemed to be equivalent.		pr	2013-12-17T14:16:04Z					cellular_component											owl:Class	
GO:0001794	biolink:NamedThing	type IIa hypersensitivity	An inflammatory response resulting in cell death mediated by activation of the classical complement pathway or induction of effector cell phagocytosis or cytolysis mechanisms via complement or Fc receptors following the binding of antibodies to cell surface antigens on a target cell.	tmpzr1t_l9r_go_relaxed.owl						Note that some type IIb hypersensitivity responses (GO:0001795) are referred to simply as type II hypersensitivity in the earlier literature, but are mechanistically distinct from type IIa hypersensitivity.								biological_process											owl:Class	
GO:0043610	biolink:NamedThing	regulation of carbohydrate utilization	Any process that modulates the frequency, rate or extent of carbohydrate utilization.	tmpzr1t_l9r_go_relaxed.owl	regulation of sugar utilization													biological_process											owl:Class	
GO:1990658	biolink:NamedThing	transnitrosylase complex	A transferase complex which is capable of transferring nitrogenous groups from one component to another.	tmpzr1t_l9r_go_relaxed.owl	transferase complex, transferring nitrogenous groups					An example of this is S100A9 in human (UniProt symbol P06702) in PMID:25417112 (inferred from direct assay).		bhm	2015-02-25T11:17:17Z					cellular_component											owl:Class	
GO:0009562	biolink:NamedThing	embryo sac nuclear migration	The directed movement of an embryo sac nucleus to the pole or center of the cell.	tmpzr1t_l9r_go_relaxed.owl	embryo sac nucleus migration|megagametophyte nucleus migration|megagametophyte nuclear migration|female gametophyte nucleus migration|female gametophyte nuclear migration													biological_process											owl:Class	
GO:0031149	biolink:NamedThing	sorocarp stalk cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a sorocarp stalk cell, any of the cellulose-covered cells that form the stalk of a sorocarp. An example of this process is found in Dictyostelium discoideum.	tmpzr1t_l9r_go_relaxed.owl	stalk cell differentiation													biological_process											owl:Class	
GO:0043131	biolink:NamedThing	erythrocyte enucleation	The process in which nucleated precursor cells lose their nucleus during erythrocyte maturation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0071973	biolink:NamedThing	bacterial-type flagellum-dependent cell motility	Cell motility due to the motion of one or more bacterial-type flagella. A bacterial-type flagellum is a motor complex composed of an extracellular helical protein filament coupled to a rotary motor embedded in the cell envelope.	tmpzr1t_l9r_go_relaxed.owl	flagellin-based flagellar cell motility|bacterial-type flagellar cell motility							mah	2010-10-21T12:00:53Z					biological_process											owl:Class	
GO:1900399	biolink:NamedThing	positive regulation of pyrimidine nucleotide biosynthetic process	Any process that activates or increases the frequency, rate or extent of pyrimidine nucleotide biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	upregulation of pyrimidine nucleotide synthesis|up regulation of pyrimidine nucleotide biosynthetic process|positive regulation of pyrimidine nucleotide biosynthesis|up-regulation of pyrimidine nucleotide biosynthetic process|upregulation of pyrimidine nucleotide biosynthetic process|activation of pyrimidine nucleotide synthesis|upregulation of pyrimidine nucleotide biosynthesis|activation of pyrimidine nucleotide formation|positive regulation of pyrimidine nucleotide anabolism|up-regulation of pyrimidine nucleotide anabolism|up-regulation of pyrimidine nucleotide synthesis|up-regulation of pyrimidine nucleotide biosynthesis|up regulation of pyrimidine nucleotide formation|up-regulation of pyrimidine nucleotide formation|activation of pyrimidine nucleotide biosynthesis|upregulation of pyrimidine nucleotide anabolism|activation of pyrimidine nucleotide anabolism|up regulation of pyrimidine nucleotide anabolism|up regulation of pyrimidine nucleotide synthesis|positive regulation of pyrimidine nucleotide synthesis|upregulation of pyrimidine nucleotide formation|activation of pyrimidine nucleotide biosynthetic process|up regulation of pyrimidine nucleotide biosynthesis|positive regulation of pyrimidine nucleotide formation							jh	2012-04-19T01:05:50Z					biological_process											owl:Class	
GO:0070365	biolink:NamedThing	hepatocyte differentiation	The process in which a relatively unspecialized cell acquires the specialized features of a hepatocyte. A hepatocyte is specialized epithelial cell that is organized into interconnected plates called lobules, and is the main structural component of the liver.	tmpzr1t_l9r_go_relaxed.owl	liver cell differentiation													biological_process											owl:Class	
GO:0034106	biolink:NamedThing	regulation of erythrocyte clearance	Any process that modulates the frequency, rate, or extent of erythrocyte clearance.	tmpzr1t_l9r_go_relaxed.owl	regulation of neocytolysis|regulation of red blood cell clearance|regulation of RBC clearance													biological_process											owl:Class	
GO:0048930	biolink:NamedThing	glial cell migration in posterior lateral line nerve	The movement of a glial cell along the axons in the posterior lateral line nerve.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0062224	biolink:NamedThing	positive regulation of somatic muscle development	Any process that increases the rate, frequency or extent of somatic muscle development.	tmpzr1t_l9r_go_relaxed.owl								dph	2020-03-13T19:03:38Z					biological_process											owl:Class	
GO:0035993	biolink:NamedThing	deltoid tuberosity development	The process whose specific outcome is the progression of the deltoid tuberosity over time, from its formation to the mature structure. The deltoid tuberosity is the region on the shaft of the humerus to which the deltoid muscle attaches. The deltoid tuberosity develops through endochondral ossification in a two-phase process; an initiating tendon-dependent phase, and a muscle-dependent growth phase.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-08-30T01:46:53Z					biological_process											owl:Class	
GO:0032637	biolink:NamedThing	interleukin-8 production	The appearance of interleukin-8 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	tmpzr1t_l9r_go_relaxed.owl	interleukin-8 biosynthetic process|IL-8 production|interleukin-8 secretion											GO:0072606|GO:0042228		biological_process											owl:Class	
GO:0072143	biolink:NamedThing	mesangial cell development	The process whose specific outcome is the progression of a mesangial cell in the kidney over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-02-24T01:44:28Z					biological_process											owl:Class	
GO:0021671	biolink:NamedThing	rhombomere 7 morphogenesis	The process in which the anatomical structure of rhombomere 7 is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0021573	biolink:NamedThing	rhombomere 7 development	The process whose specific outcome is the progression of rhombomere 7 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0001757	biolink:NamedThing	somite specification	The process in which individual somites establish identity during embryogenesis.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0004634	biolink:NamedThing	phosphopyruvate hydratase activity	Catalysis of the reaction: 2-phospho-D-glycerate = phosphoenolpyruvate + H2O.	tmpzr1t_l9r_go_relaxed.owl	enolase activity|2-phospho-D-glycerate hydro-lyase activity|2-phospho-D-glycerate hydro-lyase (phosphoenolpyruvate-forming)|2-phosphoglycerate enolase activity|phosphoenolpyruvate hydratase activity|2-phosphoglyceric dehydratase activity|14-3-2-protein|gamma-enolase activity|2-phospho-D-glycerate-hydrolase activity|2-phosphoglycerate dehydratase activity|nervous-system specific enolase				RHEA:10164|EC:4.2.1.11|Reactome:R-HSA-70494|Reactome:R-HSA-71660|MetaCyc:2PGADEHYDRAT-RXN									molecular_function											owl:Class	
GO:1990896	biolink:NamedThing	protein localization to cell cortex of cell tip	A process in which a protein is transported to, or maintained in, the cell cortex of the cell tip.	tmpzr1t_l9r_go_relaxed.owl								vw	2015-11-05T08:41:49Z					biological_process											owl:Class	
GO:0044473	biolink:NamedThing	envenomation resulting in negative regulation of calcium channel activity in other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant stopping, prevention or reduction of the activity of a calcium channel in the bitten organism.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-01-19T02:19:46Z					biological_process											owl:Class	
GO:1904032	biolink:NamedThing	regulation of t-SNARE clustering	Any process that modulates the frequency, rate or extent of t-SNARE clustering.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-03-13T21:21:38Z					biological_process											owl:Class	
GO:0072030	biolink:NamedThing	short nephron development	The process whose specific outcome is the progression of a short nephron over time, from its formation to the mature structure. Short nephrons are associated with mid-cortical and superficial glomeruli, are situated entirely in the outer medulla, and have no thin ascending limb.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-01-25T02:49:32Z					biological_process											owl:Class	
GO:0080157	biolink:NamedThing	regulation of plant-type cell wall organization or biogenesis	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving plant-type cell wall organization or biogenesis. Plant-type cell wall organization or biogenesis is a process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a cellulose- and pectin-containing cell wall.	tmpzr1t_l9r_go_relaxed.owl	regulation of plant-type cell wall organisation or biogenesis							dhl	2010-09-01T04:02:37Z					biological_process											owl:Class	
GO:0043674	biolink:NamedThing	columella	A rod-like element of the sexine and ectexine, supporting either the tectum (the layer of sexine which forms a roof over the columella), or supporting a caput (an architectural element on top of a columella).	tmpzr1t_l9r_go_relaxed.owl	sexine 1													cellular_component											owl:Class	
GO:0039640	biolink:NamedThing	viral release by cytolysis via suppression of host peptidoglycan biosynthetic process	The killing by a virus of host cell by cytolysis, caused by a virus stopping, preventing, or reducing peptidoglycan biosynthesis in the host organism. Peptidoglycans are any of a class of glycoconjugates found in bacterial cell walls.	tmpzr1t_l9r_go_relaxed.owl	viral exit by cytolysis via suppression of host peptidoglycan biosynthetic process|cytolysis by virus via suppression of host peptidoglycan biosynthetic process	https://github.com/geneontology/go-ontology/issues/18852						bf	2012-08-17T10:54:55Z					biological_process											owl:Class	
GO:0039635	biolink:NamedThing	suppression by virus of host peptidoglycan biosynthetic process	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of peptidoglycan biosynthesis in the host organism. Peptidoglycans are any of a class of glycoconjugates found in bacterial cell walls.	tmpzr1t_l9r_go_relaxed.owl	viral inhibition of host peptidoglycan biosynthesis							bf	2012-08-10T14:58:12Z					biological_process											owl:Class	
GO:0042450	biolink:NamedThing	arginine biosynthetic process via ornithine	The chemical reactions and pathways resulting in the formation of arginine (2-amino-5-guanidinopentanoic acid) via the intermediate compound ornithine.	tmpzr1t_l9r_go_relaxed.owl	arginine anabolism via ornithine|arginine formation via ornithine|arginine synthesis via ornithine													biological_process											owl:Class	
GO:0060116	biolink:NamedThing	vestibular receptor cell morphogenesis	Any process that alters the size or shape of a vestibular receptor cell.	tmpzr1t_l9r_go_relaxed.owl	vestibular hair cell morphogenesis													biological_process											owl:Class	
GO:0060118	biolink:NamedThing	vestibular receptor cell development	The process whose specific outcome is the progression of a vestibular receptor cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate.	tmpzr1t_l9r_go_relaxed.owl	vestibular hair cell development													biological_process											owl:Class	
GO:0045035	biolink:NamedThing	sensory organ precursor cell division	The series of four asymmetric divisions undergone by the sensory organ precursor cells to generate cells that have distinct cell fates. For example, in the external sensory organ, the precursor cells give rise to one multidendritic neuron and four additional cells (the socket, shaft, sheath cells and the external sense neuron).	tmpzr1t_l9r_go_relaxed.owl	sense organ precursor cell division													biological_process											owl:Class	
GO:0039573	biolink:NamedThing	suppression by virus of host complement activation	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of complement activation. The activation of complement involves the sequential proteolysis of proteins to generate enzymes with catalytic activities. The biological functions of the complement include opsonization, inflammation, lysis of immune complexes, or enhancement of the humoral immune response. For example, the virus complement control protein (VCP) of vaccinia virus, and the complement control protein of herpesvirus inhibit C3 convertase.	tmpzr1t_l9r_go_relaxed.owl	inhibition of host complement cascade by virus|inhibition of host complement factors by virus|inhibition of host complement activation by virus				VZ:811			bf						biological_process											owl:Class	
GO:0038175	biolink:NamedThing	negative regulation of SREBP signaling pathway in response to increased oxygen levels	Any process that stops, prevents or reduces the frequency, rate or extent of the SREBP signaling pathway in response to an increase in oxygen levels.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of SREBP-mediated signaling pathway in presence of oxygen|negative regulation of SREBP-mediated signaling pathway in response to increased oxygen levels							bf	2012-07-20T01:28:59Z					biological_process											owl:Class	
GO:0036295	biolink:NamedThing	cellular response to increased oxygen levels	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting an increase in the level of oxygen.	tmpzr1t_l9r_go_relaxed.owl	cellular response to raised oxygen levels					This term should be used when an increase in oxygen levels is not considered a stress response. For a hyperoxic stress response, consider instead 'cellular response to hyperoxia ; GO:0071455'.		bf	2012-07-20T01:09:39Z					biological_process											owl:Class	
GO:0016240	biolink:NamedThing	autophagosome membrane docking	The initial attachment of an autophagosome membrane to a target membrane, mediated by proteins protruding from the membrane of the vesicle and the target membrane. Docking requires only that the two membranes come close enough for these proteins to interact and adhere.	tmpzr1t_l9r_go_relaxed.owl	autophagic vacuole docking													biological_process											owl:Class	
GO:0030222	biolink:NamedThing	eosinophil differentiation	The process in which a relatively unspecialized myeloid precursor cell acquires the specializes features of an eosinophil.	tmpzr1t_l9r_go_relaxed.owl	eosinophil cell development|eosinophil development|eosinophil cell differentiation											GO:0035856		biological_process											owl:Class	
GO:0140599	biolink:NamedThing	mitotic nuclear bridge midzone membrane domain	A nuclear membrane part at the midzone of the mitotic nuclear bridge. The midzone forms a bulge that is enriched in nuclear pores that lack baskets.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/20526						pg	2021-02-10T13:39:43Z					cellular_component											owl:Class	
GO:0140512	biolink:NamedThing	mitotic nuclear bridge midzone	The central region of a mitotic nuclear bridge, distal to the main portions of the daughter nuclei.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/19946|https://github.com/geneontology/go-ontology/issues/20526						pg	2020-09-07T10:08:02Z					cellular_component											owl:Class	
GO:0036507	biolink:NamedThing	protein demannosylation	The removal of one or more mannose residues from a mannosylated protein.	tmpzr1t_l9r_go_relaxed.owl	protein de-mannosylation					Consider also annotating to the term 'mannosyl-oligosaccharide 1,2-alpha-mannosidase activity ; GO:0004571'.		bf	2015-06-11T13:57:01Z					biological_process											owl:Class	
GO:0020006	biolink:NamedThing	symbiont-containing vacuolar membrane network	Tubular network of extensions from the symbiont-containing vacuole membrane that protrude into the host cytoplasm.	tmpzr1t_l9r_go_relaxed.owl	tubulovesicular network|parasitophorous vacuolar membrane network|symbiont-containing vacuole membrane network													cellular_component											owl:Class	
GO:0002267	biolink:NamedThing	follicular dendritic cell activation involved in immune response	A change in the morphology or behavior of a follicular dendritic cell resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response.	tmpzr1t_l9r_go_relaxed.owl	follicular dendritic cell activation during immune response													biological_process											owl:Class	
GO:0060649	biolink:NamedThing	mammary gland bud elongation	The process in which the mammary gland bud grows along its axis.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-05-29T08:50:39Z					biological_process											owl:Class	
GO:0044737	biolink:NamedThing	modulation of acid-sensing ion channel in other organism	Any process in which an organism effects a change in the frequency, rate or extent of the activity of an acid-sensing ion channel (ASIC) in another organism.	tmpzr1t_l9r_go_relaxed.owl	regulation of ASIC channel in other organism|regulation of acid-sensing ion channel in other organism							jl	2012-11-06T16:51:24Z					biological_process											owl:Class	
GO:0030805	biolink:NamedThing	regulation of cyclic nucleotide catabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of cyclic nucleotides.	tmpzr1t_l9r_go_relaxed.owl	regulation of cyclic nucleotide catabolism|regulation of cyclic nucleotide breakdown|regulation of cyclic nucleotide degradation													biological_process											owl:Class	
GO:0048707	biolink:NamedThing	instar larval or pupal morphogenesis	The process, occurring during instar larval or pupal development, by which anatomical structures are generated and organized.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0001555	biolink:NamedThing	oocyte growth	The developmental growth process in which an oocyte irreversibly increases in size over time by accretion and biosynthetic production of matter similar to that already present.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0021750	biolink:NamedThing	vestibular nucleus development	The process whose specific outcome is the progression of the vestibular nucleus over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0021548	biolink:NamedThing	pons development	The process whose specific outcome is the progression of the pons over time, from its formation to the mature structure. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0061277	biolink:NamedThing	mesonephric nephron tubule formation	The developmental process pertaining to the initial formation of a mesonephric nephron tubule from unspecified parts. A mesonephric nephron tubule is an epithelial tube that is part of a nephron in the mesonephros.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-09-02T01:16:21Z					biological_process											owl:Class	
GO:0140536	biolink:NamedThing	nuclear receptor corepressor activity	A transcription corepressor activity that represses or decreases the transcription of specific gene sets via binding to a DNA-bound nuclear receptor, either on its own or as part of a complex. Nuclear receptor corepressors often act by altering chromatin structure and modifications. For example, one class of transcription nuclear receptor corepressors modifies chromatin structure through covalent modification of histones. A second class remodels the conformation of chromatin in an ATP-dependent fashion. A third class modulates interactions of DNA-bound DNA-binding transcription factors with other transcription coregulators.	tmpzr1t_l9r_go_relaxed.owl	nuclear corepressor activity	https://github.com/geneontology/go-ontology/issues/20262|https://github.com/geneontology/go-ontology/issues/20464				For usage guidance, see comment in GO:0003712 ; transcription coregulator activity.		pg	2020-11-03T13:02:08Z					molecular_function											owl:Class	
GO:0006811	biolink:NamedThing	ion transport	The directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0035077	biolink:NamedThing	ecdysone-mediated polytene chromosome puffing	The decondensing (loosening) and swelling of the chromosomal sites of hormone-responsive genes on polytene chromosomes in response to increased production of the steroid hormone 20-hydroxyecdysone (ecdysone) in Drosophila larvae approaching pupation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0019531	biolink:NamedThing	oxalate transmembrane transporter activity	Enables the transfer of oxalate from one side of a membrane to the other. Oxalate, or ethanedioic acid, occurs in many plants and is highly toxic to animals.	tmpzr1t_l9r_go_relaxed.owl	oxalic acid transporter activity													molecular_function											owl:Class	
GO:0021542	biolink:NamedThing	dentate gyrus development	The process whose specific outcome is the progression of the dentate gyrus over time, from its formation to the mature structure. The dentate gyrus is one of two interlocking gyri of the hippocampus. It contains granule cells, which project to the pyramidal cells and interneurons of the CA3 region of the ammon gyrus.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0010318	biolink:NamedThing	pyrophosphate-dependent phosphofructokinase complex, beta-subunit complex	Refers to the beta subunit of the heterodimeric complex that possesses pyrophosphate-dependent phosphofructokinase activity.	tmpzr1t_l9r_go_relaxed.owl	PFK complex, beta-subunit													cellular_component											owl:Class	
GO:0045247	biolink:NamedThing	cytosolic electron transfer flavoprotein complex	A protein complex located in the cytosol containing flavin adenine dinucleotide (FAD) that, together with an acyl-CoA dehydrogenase, forms a system that oxidizes an acyl-CoA molecule and reduces ubiquinone and other acceptors.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0021994	biolink:NamedThing	progression of neural tube closure	The process in which the neural folds are fused extending from the initial closure points.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0015168	biolink:NamedThing	glycerol transmembrane transporter activity	Enables the transfer of glycerol from one side of a membrane to the other. Glycerol is 1,2,3-propanetriol, a sweet, hygroscopic, viscous liquid, widely distributed in nature as a constituent of many lipids.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0007434	biolink:NamedThing	adult salivary gland boundary specification	Determination in an adult organism of where the salivary gland forms, the total number of salivary gland cells and how many cells are allocated to each of the specialised cell types within the salivary gland.	tmpzr1t_l9r_go_relaxed.owl	larval salivary gland determination													biological_process											owl:Class	
GO:0061605	biolink:NamedThing	molybdopterin-synthase adenylyltransferase activity	Catalysis of the reaction: ATP [molybdopterin-synthase sulfur-carrier protein]-Gly-Gly = diphosphate [molybdopterin-synthase sulfur-carrier protein]-Gly-Gly-AMP.	tmpzr1t_l9r_go_relaxed.owl					EC:2.7.7.80|RHEA:43616			dph	2014-02-11T12:01:32Z					molecular_function											owl:Class	
GO:0016342	biolink:NamedThing	catenin complex	Complex of peripheral cytoplasmic proteins (alpha-, beta- and gamma-catenin) that interact with the cytoplasmic region of uvomorulin/E-cadherin to connect it to the actin cytoskeleton.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0048861	biolink:NamedThing	leukemia inhibitory factor signaling pathway	Any series of molecular signals initiated by the binding of leukemia inhibitory factor to a receptor on the surface of the target cell, and ending with regulation of a downstream cellular process, e.g. transcription.	tmpzr1t_l9r_go_relaxed.owl	leukemia inhibitory factor signalling pathway													biological_process											owl:Class	
GO:0035619	biolink:NamedThing	root hair tip	The tip portion of an outgrowth of a root epidermal cell.	tmpzr1t_l9r_go_relaxed.owl	root hair cell tip							bf	2010-12-03T01:43:55Z					cellular_component											owl:Class	
GO:0035618	biolink:NamedThing	root hair	A long, thin projection from a root epidermal cell that contains F-actin and tubulin, and a cell wall.	tmpzr1t_l9r_go_relaxed.owl						This term is a child of 'cell projection' and not 'cell hair' to distinguish it from animal cell hairs, which are morphologically distinct.		bf	2010-12-03T01:42:40Z					cellular_component											owl:Class	
GO:0099519	biolink:NamedThing	dense core granule cytoskeletal transport	The directed movement of dense core granules along cytoskeletal fibers, such as microtubules or actin filaments.	tmpzr1t_l9r_go_relaxed.owl	dense core vesicle cytoskeletal trafficking													biological_process											owl:Class	
GO:1904787	biolink:NamedThing	positive regulation of asymmetric protein localization involved in cell fate determination	Any process that activates or increases the frequency, rate or extent of asymmetric protein localization involved in cell fate determination.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of asymmetric protein localization involved in cell fate commitment|activation of cell fate commitment, asymmetric protein localization|up regulation of asymmetric protein localization involved in cell fate commitment|upregulation of asymmetric protein localisation involved in cell fate determination|up regulation of cell fate commitment, asymmetric protein localization|activation of asymmetric protein localization resulting in cell fate commitment|positive regulation of asymmetric protein localization resulting in cell fate commitment|activation of asymmetric protein localization involved in cell fate determination|positive regulation of asymmetric protein localisation involved in cell fate determination|up regulation of asymmetric protein localisation involved in cell fate determination|upregulation of asymmetric protein localization involved in cell fate commitment|activation of asymmetric protein localisation involved in cell fate determination|positive regulation of cell fate commitment, asymmetric protein localization|up regulation of asymmetric protein localization resulting in cell fate commitment|up-regulation of asymmetric protein localization involved in cell fate determination|activation of asymmetric protein localization involved in cell fate commitment|up regulation of asymmetric protein localization involved in cell fate determination|up-regulation of asymmetric protein localization resulting in cell fate commitment|up-regulation of asymmetric protein localisation involved in cell fate determination|up-regulation of cell fate commitment, asymmetric protein localization|upregulation of asymmetric protein localization involved in cell fate determination|upregulation of asymmetric protein localization resulting in cell fate commitment|positive regulation of asymmetric protein localization involved in cell fate commitment|upregulation of cell fate commitment, asymmetric protein localization					wrm-1 in C. Elegans (Q10953) in PMID:17476329 (IMP)		es	2015-11-03T12:11:19Z					biological_process											owl:Class	
GO:0045167	biolink:NamedThing	asymmetric protein localization involved in cell fate determination	Any process in which a protein is transported to, or maintained in, a specific asymmetric distribution, resulting in the formation of daughter cells of different types.	tmpzr1t_l9r_go_relaxed.owl	asymmetric protein localization resulting in cell fate commitment|cell fate commitment, asymmetric protein localization|asymmetric protein localization involved in cell fate commitment|asymmetric protein localisation involved in cell fate determination													biological_process											owl:Class	
GO:1903896	biolink:NamedThing	positive regulation of IRE1-mediated unfolded protein response	Any process that activates or increases the frequency, rate or extent of the IRE1-mediated unfolded protein response.	tmpzr1t_l9r_go_relaxed.owl	activation of IRE1-mediated unfolded protein response|upregulation of inositol-requiring transmembrane kinase/endonuclease signal transduction|upregulation of IRE1 branch of UPR|activation of UPR signaling by IRE1 stress sensor|upregulation of IRE1 signaling in response to endoplasmic reticulum stress|positive regulation of IRE1 signaling in response to endoplasmic reticulum stress|positive regulation of IRE1p unfolded protein response|upregulation of IRE1alpha unfolded protein response|positive regulation of IRE1 branch of UPR|upregulation of IRE1-mediated unfolded protein response|activation of inositol-requiring transmembrane kinase/endonuclease signal transduction|up regulation of endoplasmic reticulum unfolded protein response; IRE1 signaling|activation of IRE1p unfolded protein response|up regulation of IRE1alpha unfolded protein response|up regulation of IRE1-mediated unfolded protein response|up-regulation of UPR signaling by IRE1 stress sensor|up-regulation of IRE1p unfolded protein response|upregulation of IRE1p unfolded protein response|up regulation of IRE1 branch of UPR|up-regulation of IRE1alpha unfolded protein response|upregulation of endoplasmic reticulum unfolded protein response; IRE1 signaling|activation of IRE1 branch of UPR|positive regulation of UPR signaling by IRE1 stress sensor|up regulation of UPR signaling by IRE1 stress sensor|positive regulation of endoplasmic reticulum unfolded protein response; IRE1 signaling|activation of endoplasmic reticulum unfolded protein response; IRE1 signaling|positive regulation of ERN1-mediated unfolded protein response|activation of IRE1 signaling in response to endoplasmic reticulum stress|upregulation of UPR signaling by IRE1 stress sensor|up regulation of inositol-requiring transmembrane kinase/endonuclease signal transduction|up-regulation of inositol-requiring transmembrane kinase/endonuclease signal transduction|positive regulation of IRE1alpha unfolded protein response|up-regulation of IRE1-mediated unfolded protein response|up-regulation of IRE1 branch of UPR|up regulation of IRE1p unfolded protein response|up-regulation of endoplasmic reticulum unfolded protein response; IRE1 signaling|positive regulation of inositol-requiring transmembrane kinase/endonuclease signal transduction|up regulation of IRE1 signaling in response to endoplasmic reticulum stress|up-regulation of IRE1 signaling in response to endoplasmic reticulum stress|activation of IRE1alpha unfolded protein response							bf	2015-02-09T10:18:04Z					biological_process											owl:Class	
GO:0002291	biolink:NamedThing	T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell	The change in morphology and behavior of a mature or immature T cell resulting from exposure to an antigen for which its T cell receptor is specific bound to an MHC molecule on an antigen presenting cell, leading to the initiation or perpetuation of an immune response.	tmpzr1t_l9r_go_relaxed.owl	T-cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell|T lymphocyte activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell|T-lymphocyte activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell													biological_process											owl:Class	
GO:0003309	biolink:NamedThing	type B pancreatic cell differentiation	The process in which relatively unspecialized cells acquire specialized structural and/or functional features of a type B pancreatic cell. A type B pancreatic cell is a cell located towards center of the islets of Langerhans that secretes insulin.	tmpzr1t_l9r_go_relaxed.owl	pancreatic beta cell differentiation|pancreatic B cell differentiation							dph	2009-10-26T09:27:23Z					biological_process											owl:Class	
GO:0050917	biolink:NamedThing	sensory perception of umami taste	The series of events required to receive an umami taste stimulus, convert it to a molecular signal, and recognize and characterize the signal. Umami taste is the savory taste of meats and other foods that are rich in glutamates. This is a neurological process.	tmpzr1t_l9r_go_relaxed.owl	umami taste perception													biological_process											owl:Class	
GO:0042471	biolink:NamedThing	ear morphogenesis	The process in which the anatomical structures of the ear are generated and organized. The ear is the sense organ in vertebrates that is specialized for the detection of sound, and the maintenance of balance. Includes the outer ear and middle ear, which collect and transmit sound waves; and the inner ear, which contains the organs of balance and (except in fish) hearing. Also includes the pinna, the visible part of the outer ear, present in some mammals.	tmpzr1t_l9r_go_relaxed.owl	hearing organ morphogenesis													biological_process											owl:Class	
GO:0033526	biolink:NamedThing	tetrapyrrole biosynthetic process from glutamate	The chemical reactions and pathways leading to the formation of tetrapyrroles, natural pigments containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next, from other compounds, including L-glutamate.	tmpzr1t_l9r_go_relaxed.owl	tetrapyrrole anabolism from glutamate|tetrapyrrole synthesis from glutamate|tetrapyrrole biosynthesis from glutamate|tetrapyrrole formation from glutamate				MetaCyc:PWY-5188									biological_process											owl:Class	
GO:0008837	biolink:NamedThing	diaminopimelate epimerase activity	Catalysis of the reaction: LL-2,6-diaminopimelate = meso-2,6-diaminopimelate.	tmpzr1t_l9r_go_relaxed.owl	LL-2,6-diaminoheptanedioate 2-epimerase activity				KEGG_REACTION:R02735|EC:5.1.1.7|RHEA:15393|MetaCyc:DIAMINOPIMEPIM-RXN									molecular_function											owl:Class	
GO:0062167	biolink:NamedThing	complement component C1q complex	A protein-containing complex composed of six subunits of each of the three homologous polypeptide chains C1QA, C1QB, and C1QB. It is a subunit of the complement C1 complex. In addition to complement activation, C1q appears to have roles in homeostasis and cellular development, superoxide (O2-) production by neutrophils, blood coagulation and neurological synapse pruning.	tmpzr1t_l9r_go_relaxed.owl	C1q|Complement 1q							dph	2019-11-12T13:21:57Z					cellular_component											owl:Class	
GO:0072294	biolink:NamedThing	specification of metanephric connecting tubule identity	The process in which the connecting tubule of the metanephric nephron acquires its identity.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-04-09T04:00:31Z					biological_process											owl:Class	
GO:0072286	biolink:NamedThing	metanephric connecting tubule development	The process whose specific outcome is the progression of the metanephric connecting tubule over time, from its formation to the mature structure. The metanephric connecting tubule is a tubular segment of the metanephric nephron; it connects the distal convoluted tubule to the collecting duct in the metanephros.	tmpzr1t_l9r_go_relaxed.owl	metanephric connecting duct development							mah	2010-04-09T03:30:09Z					biological_process											owl:Class	
GO:0044458	biolink:NamedThing	motile cilium assembly	The aggregation, arrangement and bonding together of a set of components to form a motile cilium.	tmpzr1t_l9r_go_relaxed.owl	nodal cilium assembly|motile primary cilia formation|nodal cilium formation|motile primary cilium assembly|motile primary cilia assembly|motile primary cilium formation							krc	2015-02-06T17:23:23Z			GO:1903887		biological_process											owl:Class	
GO:0016360	biolink:NamedThing	sensory organ precursor cell fate determination	The process in which a cell becomes capable of differentiating autonomously into a sensory organ precursor cell regardless of its environment; upon determination, the cell fate cannot be reversed.	tmpzr1t_l9r_go_relaxed.owl	sense organ precursor cell fate determination													biological_process											owl:Class	
GO:0017050	biolink:NamedThing	D-erythro-sphingosine kinase activity	Catalysis of the reaction: sphingosine + ATP = sphingosine 1-phosphate + ADP.	tmpzr1t_l9r_go_relaxed.owl	sphingosine kinase activity				Reactome:R-HSA-428273|MetaCyc:RXN3DJ-11417|Reactome:R-HSA-9695949|Reactome:R-HSA-5218845|Reactome:R-HSA-9625814|RHEA:35847									molecular_function											owl:Class	
GO:0030433	biolink:NamedThing	ubiquitin-dependent ERAD pathway	The series of steps necessary to target endoplasmic reticulum (ER)-resident proteins for degradation by the cytoplasmic proteasome. Begins with recognition of the ER-resident protein, includes retrotranslocation (dislocation) of the protein from the ER to the cytosol, protein ubiquitination necessary for correct substrate transfer, transport of the protein to the proteasome, and ends with degradation of the protein by the cytoplasmic proteasome.	tmpzr1t_l9r_go_relaxed.owl	ER-associated ubiquitin-dependent protein degradation|ER-associated ubiquitin-dependent protein catabolic process|ERAD|ER-associated ubiquitin-dependent protein catabolism|endoplasmic reticulum-associated ubiquitin-dependent protein catabolic process|endoplasmic reticulum-associated ubiqutin-dependent protein catabolism|ubiquitin-dependent proteasomal protein catabolism of ER proteins|ER-associated ubiquitin-dependent protein breakdown					See also the biological process terms 'ERAD pathway ; GO:0036503', 'unfolded protein response ; GO:0030968' and 'retrograde protein transport, ER to cytosol ; GO:0030970'.								biological_process											owl:Class	
GO:0030993	biolink:NamedThing	axonemal heterotrimeric kinesin-II complex	A kinesin complex found in eukaryotic axonemes that contains two distinct plus end-directed kinesin motor proteins and at least one accessory subunit, and that functions in the anterograde transport of molecules (cargo) from the basal body to the distal tip of the axoneme.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0097433	biolink:NamedThing	dense body	An electron dense body which may contain granules.	tmpzr1t_l9r_go_relaxed.owl					NIF_Subcellular:sao730872736			pr	2012-11-22T15:34:04Z					cellular_component											owl:Class	
GO:0032172	biolink:NamedThing	germ tube septin ring	A tight ring-shaped structure that forms in the division plane within the germ tube of filamentous fungi at sites where a septum will form; composed of septins as well as septin-associated proteins.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0003387	biolink:NamedThing	neuron differentiation involved in amphid sensory organ development	The process in which a relatively unspecialized cell acquires specialized features of a neuron that contributes to the progression of the amphid sensory gland.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-12-09T09:15:00Z					biological_process											owl:Class	
GO:0003386	biolink:NamedThing	amphid sensory organ development	The progression of the amphid sensory organ over time, from its formation to the mature structure. Amphid sensory organs are the sensory organs of nematodes.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-12-09T09:09:20Z					biological_process											owl:Class	
GO:0010689	biolink:NamedThing	negative regulation of ribosomal protein gene transcription from RNA polymerase II promoter in response to chemical stimulus	Any process that decreases the frequency, rate or extent of the synthesis of RNA from ribosomal protein genes by RNA polymerase II, originating at an RNA polymerase II promoter, as a result of a chemical stimulus.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0098529	biolink:NamedThing	neuromuscular junction development, skeletal muscle fiber	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a neuromuscular junction that targets a skeletal muscle fiber.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0048741	biolink:NamedThing	skeletal muscle fiber development	The process whose specific outcome is the progression of the skeletal muscle fiber over time, from its formation to the mature structure. Muscle fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast.	tmpzr1t_l9r_go_relaxed.owl	skeletal muscle fibre development|skeletal myofiber development|skeletal myofibre development													biological_process											owl:Class	
GO:0038004	biolink:NamedThing	epidermal growth factor receptor ligand maturation	Any process leading to the attainment of the full functional capacity of a ligand for an epidermal growth factor receptor. The ligand is functional when it can bind to and activate an epidermal growth factor receptor.	tmpzr1t_l9r_go_relaxed.owl	peptide bond cleavage involved in epidermal growth factor receptor ligand maturation|peptide bond cleavage involved in EGFR ligand maturation|EGFR ligand processing|EGFR ligand maturation|epidermal growth factor receptor ligand processing|EGFR ligand maturation by peptide bond cleavage							bf	2011-06-07T03:08:41Z			GO:0038005		biological_process											owl:Class	
GO:1903278	biolink:NamedThing	positive regulation of sodium ion export across plasma membrane	Any process that activates or increases the frequency, rate or extent of sodium ion export across the plasma membrane.	tmpzr1t_l9r_go_relaxed.owl	up regulation of sodium ion export|up regulation of sodium export|activation of sodium ion export from cell|upregulation of sodium export|activation of sodium ion export|positive regulation of sodium ion export from cell|upregulation of sodium ion export from cell|positive regulation of sodium ion export|up-regulation of sodium export|positive regulation of sodium export|upregulation of sodium ion export|up-regulation of sodium ion export from cell|up-regulation of sodium ion export|activation of sodium export|up regulation of sodium ion export from cell							rl	2014-08-08T17:10:30Z			GO:1903275		biological_process											owl:Class	
GO:0015244	biolink:NamedThing	fluconazole transmembrane transporter activity	Enables the transfer of fluconazole from one side of a membrane to the other. Fluconazole is an antifungal drug used for oral candidiasis and cryptococcal meningitis; it is still under study for treatment of vaginal candidiasis and other fungal infections.	tmpzr1t_l9r_go_relaxed.owl	fluconazole transporter activity													molecular_function											owl:Class	
GO:0007202	biolink:NamedThing	activation of phospholipase C activity	The initiation of the activity of the inactive enzyme phospolipase C as the result of a series of molecular signals generated as a consequence of a G protein-coupled receptor binding to its physiological ligand.	tmpzr1t_l9r_go_relaxed.owl	phospholipase C activation					Note that this term refers to a signaling pathway, and should not be confused with function terms such as 'phospholipase activator activity ; GO:0016004'.								biological_process											owl:Class	
GO:0043124	biolink:NamedThing	negative regulation of I-kappaB kinase/NF-kappaB signaling	Any process that stops, prevents, or reduces the frequency, rate or extent of -kappaB kinase/NF-kappaB signaling.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of I-kappaB kinase/NF-kappaB cascade|down-regulation of I-kappaB kinase/NF-kappaB cascade|down regulation of I-kappaB kinase/NF-kappaB cascade|inhibition of I-kappaB kinase/NF-kappaB cascade|downregulation of I-kappaB kinase/NF-kappaB cascade													biological_process											owl:Class	
GO:0150064	biolink:NamedThing	vertebrate eye-specific patterning	Early postnatal vertebrate developmental process, during which axons of retinal ganglion cells (RGCs), transmitting overlapping inputs from both eyes, segregate into distinct eye-specific non-overlapping regions in the dorsal lateral geniculate nucleus (dLGN) of the thalamus.	tmpzr1t_l9r_go_relaxed.owl	eye-specific patterning|eye-specific segregation|binocular vision development|vertebrate eye-specific segregation							bc	2018-07-23T10:39:44Z					biological_process											owl:Class	
GO:0000485	biolink:NamedThing	cleavage between 2S rRNA and LSU-rRNA of tetracistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, 2S rRNA, LSU-rRNA)	Endonucleolytic cleavage between the LSU-rRNA and the 2S rRNA of an rRNA molecule originally produced as a tetracistronic rRNA transcript that contained the Small SubUnit (SSU) rRNA, the 5.8S rRNA, 2S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0000473	biolink:NamedThing	maturation of LSU-rRNA from tetracistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, 2S rRNA, LSU-rRNA)	Any process involved in the maturation of a precursor Large SubUnit (LSU) ribosomal RNA (rRNA) molecule into a mature LSU-rRNA molecule from the pre-rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, 5.8 S rRNA, 2S rRNA, and Large Subunit (LSU) in that order from 5' to 3' along the primary transcript.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1990116	biolink:NamedThing	ribosome-associated ubiquitin-dependent protein catabolic process	The chemical reactions and pathways resulting in the breakdown of a protein or peptide encoded by an aberrant message and associated with a stalled ribosome. Degradation is initiated by the covalent attachment of a ubiquitin group, or multiple ubiquitin groups, to the ribosome-associated protein.	tmpzr1t_l9r_go_relaxed.owl	ribosome-associated degradation|ribosome-associated ubiquitin-dependent protein breakdown|ribosome-associated ubiquitin-dependent protein degradation|RAD|ribosome-associated ubiquitin-dependent protein catabolism							pr	2013-06-05T11:46:01Z					biological_process											owl:Class	
GO:0032639	biolink:NamedThing	TRAIL production	The appearance of TRAIL due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	tmpzr1t_l9r_go_relaxed.owl	TRAIL biosynthetic process					Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.						GO:0045553		biological_process											owl:Class	
GO:0010603	biolink:NamedThing	regulation of cytoplasmic mRNA processing body assembly	Any process that modulates the rate, frequency, or extent of the aggregation, arrangement and bonding together of proteins and RNA molecules to form a cytoplasmic mRNA processing body.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1901220	biolink:NamedThing	negative regulation of cardiac chamber morphogenesis	Any process that stops, prevents or reduces the frequency, rate or extent of cardiac chamber morphogenesis.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of heart chamber morphogenesis|down-regulation of cardiac chamber morphogenesis|inhibition of cardiac chamber morphogenesis|inhibition of heart chamber morphogenesis|down regulation of cardiac chamber morphogenesis|downregulation of heart chamber morphogenesis|negative regulation of heart chamber morphogenesis|downregulation of cardiac chamber morphogenesis|down regulation of heart chamber morphogenesis							rl	2012-08-06T17:59:34Z					biological_process											owl:Class	
GO:0048162	biolink:NamedThing	multi-layer follicle stage	The stage in oogenesis when many layers of follicle cells surround the oocyte. There is a yolk nucleus (Balbiani's Body) near the germinal vesicle.	tmpzr1t_l9r_go_relaxed.owl	mammalian oogenesis stage 5													biological_process											owl:Class	
GO:0051601	biolink:NamedThing	exocyst localization	Any process in which an exocyst is transported to, or maintained in, a specific location. An exocyst is a protein complex peripherally associated with the plasma membrane that determines where vesicles dock and fuse.	tmpzr1t_l9r_go_relaxed.owl	establishment and maintenance of exocyst localization|exocyst localisation													biological_process											owl:Class	
GO:1904196	biolink:NamedThing	negative regulation of granulosa cell proliferation	Any process that stops, prevents or reduces the frequency, rate or extent of granulosa cell proliferation.	tmpzr1t_l9r_go_relaxed.owl	down regulation of granulosa cell proliferation|inhibition of granulosa cell proliferation|down-regulation of granulosa cell proliferation|downregulation of granulosa cell proliferation							sl	2015-05-07T17:02:34Z					biological_process											owl:Class	
GO:0061651	biolink:NamedThing	Atg12 conjugating enzyme activity	Isoenergetic transfer of Atg12 from one protein to another via the reaction X-Atg12 + Y -> Y-Atg12 + X, where both the X-Atg12 and Y-Atg12 linkages are thioester bonds between the C-terminal amino acid of Atg12 and a sulfhydryl side group of a cysteine residue.	tmpzr1t_l9r_go_relaxed.owl	E2							dph	2014-11-06T13:17:36Z					molecular_function											owl:Class	
GO:0003301	biolink:NamedThing	physiological cardiac muscle hypertrophy	The enlargement or overgrowth of all or part of the heart muscle due to an increase in size of cardiac muscle cells without cell division. This process contributes to the developmental growth of the heart.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-10-22T10:38:10Z					biological_process											owl:Class	
GO:1902990	biolink:NamedThing	mitotic telomere maintenance via semi-conservative replication	Any telomere maintenance via semi-conservative replication that is involved in mitotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl	telomeric replication fork progression involved in mitotic cell cycle|telomeric fork progression involved in mitotic cell cycle|equal telomere replication involved in mitotic cell cycle							jl	2014-05-08T11:13:49Z					biological_process											owl:Class	
GO:0001963	biolink:NamedThing	synaptic transmission, dopaminergic	The vesicular release of dopamine. from a presynapse, across a chemical synapse, the subsequent activation of dopamine receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse.	tmpzr1t_l9r_go_relaxed.owl	dopaminergic synaptic transmission													biological_process											owl:Class	
GO:0036478	biolink:NamedThing	L-dopa decarboxylase activator activity	Interacts with and increases L-dopa decarboxylase activity.	tmpzr1t_l9r_go_relaxed.owl	DDC activator activity					GO:0036478 is reserved for cases when the activator directly interacts with L-dopa decarboxylase. When activation of L-dopa decarboxylase activity is achieved without enzyme binding, or when the mechanism of regulation is unknown, instead annotate to 'positive regulation of L-dopa decarboxylase activity ; GO:1903200'.		bf	2014-07-24T10:10:51Z					molecular_function											owl:Class	
GO:1903200	biolink:NamedThing	positive regulation of L-dopa decarboxylase activity	Any process that activates or increases the frequency, rate or extent of L-dopa decarboxylase activity.	tmpzr1t_l9r_go_relaxed.owl	upregulation of 4-dihydroxyl-L-phenylalanine decarboxylase activity|up regulation of DOPA decarboxylase activity|upregulation of L-dopa decarboxylase activity|positive regulation of DOPA decarboxylase activity|activation of 4-dihydroxyl-L-phenylalanine decarboxylase activity|activation of DDC activity|up-regulation of DOPA decarboxylase activity|upregulation of DDC activity|activation of L-dopa decarboxylase activity|up regulation of L-dopa decarboxylase activity|positive regulation of 4-dihydroxyl-L-phenylalanine decarboxylase activity|activation of DOPA decarboxylase activity|up-regulation of 4-dihydroxyl-L-phenylalanine decarboxylase activity|up-regulation of DDC activity|up-regulation of L-dopa decarboxylase activity|up regulation of 4-dihydroxyl-L-phenylalanine decarboxylase activity|up regulation of DDC activity|upregulation of DOPA decarboxylase activity|positive regulation of DDC activity							bf	2014-07-21T09:32:43Z					biological_process											owl:Class	
GO:0036177	biolink:NamedThing	filamentous growth of a population of unicellular organisms in response to pH	The process in which a group of unicellular organisms grow in a threadlike, filamentous shape in response to a pH stimulus. pH is a measure of the acidity or basicity of an aqueous solution.	tmpzr1t_l9r_go_relaxed.owl								bf	2012-03-29T01:43:04Z					biological_process											owl:Class	
GO:0007529	biolink:NamedThing	establishment of synaptic specificity at neuromuscular junction	The biological process in which a synapse between a motor neuron and a muscle is initially formed.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0007528	biolink:NamedThing	neuromuscular junction development	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a neuromuscular junction.	tmpzr1t_l9r_go_relaxed.owl	NMJ stability|neuromuscular junction organization|neuromuscular junction stability													biological_process											owl:Class	
GO:0009427	biolink:NamedThing	bacterial-type flagellum basal body, distal rod, L ring	One of the rings of the bacterial-type flagellar basal body; anchors the basal body to the outer membrane.	tmpzr1t_l9r_go_relaxed.owl	flagellar basal body, distal rod, L ring|flagellin-based flagellum basal body, distal rod, L ring													cellular_component											owl:Class	
GO:0009426	biolink:NamedThing	bacterial-type flagellum basal body, distal rod	The portion of the central rod of the bacterial-type flagellar basal body that is distal to the cell membrane; spans most of the distance between the inner and outer membranes.	tmpzr1t_l9r_go_relaxed.owl	flagellin-based flagellum basal body, distal rod|flagellar basal body, distal rod													cellular_component											owl:Class	
GO:0001833	biolink:NamedThing	inner cell mass cell proliferation	The proliferation of cells in the inner cell mass.	tmpzr1t_l9r_go_relaxed.owl						See also the Anatomical Dictionary for Mouse Development ontology terms 'TS4, inner cell mass ; EMAP:14' and 'TS5, inner cell mass ; EMAP:24'.								biological_process											owl:Class	
GO:0010698	biolink:NamedThing	acetyltransferase activator activity	Binds to and increases the activity of an acetyltransferase, an enzyme which catalyzes the transfer of an acetyl group to an acceptor molecule.	tmpzr1t_l9r_go_relaxed.owl	acetyltransferase stimulator activity													molecular_function											owl:Class	
GO:0001701	biolink:NamedThing	in utero embryonic development	The process whose specific outcome is the progression of the embryo in the uterus over time, from formation of the zygote in the oviduct, to birth. An example of this process is found in Mus musculus.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0035600	biolink:NamedThing	tRNA methylthiolation	The addition of a methylthioether group (-SCH3) to a nucleotide in a tRNA molecule.	tmpzr1t_l9r_go_relaxed.owl								bf	2010-11-12T01:34:02Z					biological_process											owl:Class	
GO:1902830	biolink:NamedThing	negative regulation of spinal cord association neuron differentiation	Any process that stops, prevents or reduces the frequency, rate or extent of spinal cord association neuron differentiation.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of spinal cord dorsal interneuron differentiation|downregulation of spinal cord association neuron differentiation|down-regulation of spinal cord association neuron differentiation|inhibition of spinal cord association neuron differentiation|inhibition of spinal cord dorsal interneuron differentiation|down regulation of spinal cord dorsal interneuron differentiation|down regulation of spinal cord association neuron differentiation|downregulation of spinal cord dorsal interneuron differentiation|down-regulation of spinal cord dorsal interneuron differentiation							mr	2014-03-31T17:11:55Z					biological_process											owl:Class	
GO:0051486	biolink:NamedThing	isopentenyl diphosphate biosynthetic process, mevalonate pathway involved in terpenoid biosynthetic process	The chemical reactions and pathways resulting in the formation of isopentenyl diphosphate by the mevalonate pathway that contributes to terpenoid biosynthesis. This pathway converts acetate, in the form of acetyl-CoA, to isopentenyl diphosphate (IPP) through a series of mevalonate intermediates.	tmpzr1t_l9r_go_relaxed.owl	isopentenyl diphosphate formation, mevalonate pathway, during terpenoid biosynthesis|isopentenyl diphosphate biosynthetic process, mevalonate pathway, during terpenoid biosynthetic process|isopentenyl diphosphate synthesis, mevalonate pathway, during terpenoid synthesis|isopentenyl diphosphate formation, mevalonate pathway, during terpenoid formation|isopentenyl diphosphate anabolism, mevalonate pathway, during terpenoid anabolism													biological_process											owl:Class	
GO:0051079	biolink:NamedThing	meiosis I nuclear membrane disassembly	The controlled breakdown of the nuclear membranes during the first division of meiosis.	tmpzr1t_l9r_go_relaxed.owl	meiosis I nuclear envelope degradation|meiosis I nuclear envelope catabolism|meiosis I nuclear envelope disassembly|meiosis I nuclear envelope breakdown													biological_process											owl:Class	
GO:0071839	biolink:NamedThing	apoptotic process in bone marrow cell	The apoptotic process in cells in the bone marrow.	tmpzr1t_l9r_go_relaxed.owl	killing of bone marrow cells|apoptosis in bone marrow|programmed cell death of bone marrow cells by apoptosis|bone marrow cell programmed cell death by apoptosis|bone marrow cell apoptosis|programmed cell death, bone marrow cells							mah	2010-09-10T12:19:18Z					biological_process											owl:Class	
GO:0033557	biolink:NamedThing	Slx1-Slx4 complex	A heterodimeric protein complex that possesses an endonuclease activity that specifically cleaves certain types of branched DNA structures; because such structures often form during the replication ribosomal DNA (rDNA) repeats, the complex plays a role in the maintenance of rDNA. The subunits are known as Slx1 and Slx 4 in budding and fission yeasts, and are conserved in eukaryotes.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0070057	biolink:NamedThing	prospore membrane spindle pole body attachment site	The region of the prospore membrane to which the spindle pole body (SPB) is anchored; the prospore membrane extends from the SPB attachment site to surround the spore nucleus.	tmpzr1t_l9r_go_relaxed.owl	forespore membrane SPB attachment site|forespore membrane spindle pole body attachment site|prospore membrane SPB attachment site													cellular_component											owl:Class	
GO:0004913	biolink:NamedThing	interleukin-4 receptor activity	Combining with interleukin-4 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	IL-4 receptor activity|IL-4R													molecular_function											owl:Class	
GO:0003163	biolink:NamedThing	sinoatrial node development	The process whose specific outcome is the progression of the sinoatrial (SA) node over time, from its formation to the mature structure. The SA node is part of the cardiac conduction system that controls the timing of heart muscle contraction. It relays electrical signals to the AV node.	tmpzr1t_l9r_go_relaxed.owl	SAN development|SA node development|sinus node development							dph	2009-10-01T02:06:09Z					biological_process											owl:Class	
GO:0038092	biolink:NamedThing	nodal signaling pathway	A series of molecular signals initiated by the binding of a nodal protein to an activin receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.	tmpzr1t_l9r_go_relaxed.owl	nodal signaling|nodal signalling pathway							bf	2012-02-16T02:44:02Z					biological_process											owl:Class	
GO:2000473	biolink:NamedThing	positive regulation of hematopoietic stem cell migration	Any process that activates or increases the frequency, rate or extent of hematopoietic stem cell migration.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of hemopoietic stem cell migration							bf	2011-03-09T09:35:25Z					biological_process											owl:Class	
GO:0036516	biolink:NamedThing	chemoattraction of dopaminergic neuron axon	The process in which a dopaminergic neuron growth cone is directed to a specific target site in response to an attractive chemical signal.	tmpzr1t_l9r_go_relaxed.owl	chemoattraction of DA axon|chemoattraction of dopaminergic axon							bf	2015-12-17T11:23:11Z					biological_process											owl:Class	
GO:0036514	biolink:NamedThing	dopaminergic neuron axon guidance	The chemotaxis process that directs the migration of an axon growth cone of a dopaminergic neuron to a specific target site in response to a combination of attractive and repulsive cues.	tmpzr1t_l9r_go_relaxed.owl	mdDA axon guidance|DA axon guidance|dopaminergic axon guidance							bf	2015-12-17T11:14:20Z					biological_process											owl:Class	
GO:0061318	biolink:NamedThing	renal filtration cell differentiation	The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a renal filtration cell. Renal filtration cells are specialized cells of the renal system that filter fluids by charge, size or both. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-09-24T12:18:35Z					biological_process											owl:Class	
GO:1903373	biolink:NamedThing	positive regulation of endoplasmic reticulum tubular network organization	Any process that activates or increases the frequency, rate or extent of endoplasmic reticulum tubular network organization.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of endoplasmic reticulum tubular network organization|positive regulation of ER tubular network organization|up regulation of ER tubular network organisation|activation of endoplasmic reticulum tubular network organization|up-regulation of ER tubular network organisation|activation of ER tubular network organization|up regulation of endoplasmic reticulum tubular network organisation|upregulation of ER tubular network organization|up regulation of endoplasmic reticulum tubular network organization|positive regulation of endoplasmic reticulum tubular network organisation|activation of endoplasmic reticulum tubular network organisation|upregulation of endoplasmic reticulum tubular network organization|upregulation of endoplasmic reticulum tubular network organisation|up-regulation of ER tubular network organization|upregulation of ER tubular network organisation|activation of ER tubular network organisation|positive regulation of ER tubular network organisation|up-regulation of endoplasmic reticulum tubular network organisation|up regulation of ER tubular network organization							als	2014-08-22T11:01:31Z					biological_process											owl:Class	
GO:0061674	biolink:NamedThing	gap filling involved in double-strand break repair via nonhomologous end joining	Repair of the gaps in the DNA helix using a discontinuous template during double-strand break repair via nonhomologous end joining.	tmpzr1t_l9r_go_relaxed.owl								dph	2015-01-05T10:07:32Z					biological_process											owl:Class	
GO:0140249	biolink:NamedThing	protein catabolic process at postsynapse	The chemical reactions and pathways resulting in the breakdown of a protein at a postsynapse.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/synapse/issues/204				Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.		pg	2018-07-15T10:25:04Z					biological_process											owl:Class	
GO:2000758	biolink:NamedThing	positive regulation of peptidyl-lysine acetylation	Any process that activates or increases the frequency, rate or extent of peptidyl-lysine acetylation.	tmpzr1t_l9r_go_relaxed.owl								yaf	2011-06-16T09:51:35Z					biological_process											owl:Class	
GO:0061612	biolink:NamedThing	galactose to glucose-1-phosphate metabolic process	The chemical reactions and pathways in which galactose, the aldohexose galacto-hexose, is converted to glucose-1-phosphate.	tmpzr1t_l9r_go_relaxed.owl								dph	2014-04-04T08:18:49Z					biological_process											owl:Class	
GO:0003978	biolink:NamedThing	UDP-glucose 4-epimerase activity	Catalysis of the reaction: UDP-glucose = UDP-galactose.	tmpzr1t_l9r_go_relaxed.owl	UDPgalactose 4-epimerase activity|uridine diphosphoglucose epimerase activity|uridine diphosphoglucose 4-epimerase activity|UDPglucose 4-epimerase activity|UDP-D-galactose 4-epimerase activity|uridine diphospho-galactose-4-epimerase activity|uridine diphosphate glucose 4-epimerase activity|UDPG-4-epimerase activity|4-epimerase activity|galactowaldenase activity|UDP-glucose epimerase activity|uridine diphosphate galactose 4-epimerase activity|UDP-galactose 4-epimerase activity				EC:5.1.3.2|Reactome:R-HSA-5610036|MetaCyc:UDPGLUCEPIM-RXN|Reactome:R-HSA-70369|RHEA:22168									molecular_function											owl:Class	
GO:0014018	biolink:NamedThing	neuroblast fate specification	The process in which a cell becomes capable of differentiating autonomously into a neuroblast in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0014017	biolink:NamedThing	neuroblast fate commitment	The process in which the developmental fate of a cell becomes restricted such that it will differentiate into a neuroblast.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0032106	biolink:NamedThing	positive regulation of response to extracellular stimulus	Any process that activates, maintains or increases the rate of a response to an extracellular stimulus.	tmpzr1t_l9r_go_relaxed.owl	activation of response to extracellular stimulus|up-regulation of response to extracellular stimulus|upregulation of response to extracellular stimulus|up regulation of response to extracellular stimulus|stimulation of response to extracellular stimulus													biological_process											owl:Class	
GO:0002265	biolink:NamedThing	astrocyte activation involved in immune response	A change in the morphology or behavior of an astrocyte resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response.	tmpzr1t_l9r_go_relaxed.owl	astrocyte activation during immune response													biological_process											owl:Class	
GO:0048628	biolink:NamedThing	myoblast maturation	A developmental process, independent of morphogenetic (shape) change, that is required for a myoblast to attain its fully functional state. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0048627	biolink:NamedThing	myoblast development	The process whose specific outcome is the progression of the myoblast over time, from its formation to the mature structure. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0031240	biolink:NamedThing	external side of cell outer membrane	The side of the outer membrane that is opposite to the side that faces the periplasm of the cell.	tmpzr1t_l9r_go_relaxed.owl	external side of outer membrane|external leaflet of cell outer membrane					In GO, 'external side' still refers to part of the membrane and does not refer to components beyond (outside of) the membrane.								cellular_component											owl:Class	
GO:0002457	biolink:NamedThing	T cell antigen processing and presentation	The process in which a T cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex.	tmpzr1t_l9r_go_relaxed.owl	T-lymphocyte antigen processing and presentation|T-cell antigen processing and presentation|T lymphocyte antigen processing and presentation													biological_process											owl:Class	
GO:0034196	biolink:NamedThing	acylglycerol transport	The directed movement of an acylglycerol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. An acylglycerol is any mono-, di- or triester of glycerol with (one or more) fatty acids.	tmpzr1t_l9r_go_relaxed.owl	glyceride transport													biological_process											owl:Class	
GO:0035578	biolink:NamedThing	azurophil granule lumen	The volume enclosed by the membrane of an azurophil granule, a primary lysosomal granule found in neutrophil granulocytes that contains a wide range of hydrolytic enzymes and is released into the extracellular fluid.	tmpzr1t_l9r_go_relaxed.owl	primary granule lumen							bf	2010-10-05T01:30:33Z					cellular_component											owl:Class	
GO:0038025	biolink:NamedThing	reelin receptor activity	Combining with the secreted glycoprotein reelin, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	reeler receptor activity							bf	2011-08-02T12:01:25Z					molecular_function											owl:Class	
GO:0038026	biolink:NamedThing	reelin-mediated signaling pathway	A series of molecular signals initiated by the binding of reelin (a secreted glycoprotein) to a receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.	tmpzr1t_l9r_go_relaxed.owl	reelin-mediated signalling pathway|reelin-mediated signal transduction pathway|reeler-mediated signaling pathway							bf	2011-08-02T02:06:18Z					biological_process											owl:Class	
GO:1902978	biolink:NamedThing	premeiotic DNA replication termination	Any DNA replication termination involved in meiotic cell cycle DNA replication.	tmpzr1t_l9r_go_relaxed.owl	DNA replication termination involved in meiotic cell cycle DNA replication|DNA replication termination involved in meiotic DNA replication							jl	2014-05-06T19:19:43Z					biological_process											owl:Class	
GO:0150003	biolink:NamedThing	regulation of spontaneous synaptic transmission	Any process that modulates the frequency, rate or extent of spontaneous synaptic transmission.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:2000892	biolink:NamedThing	cellobiose catabolic process	The chemical reactions and pathways resulting in the breakdown of a cellobiose.	tmpzr1t_l9r_go_relaxed.owl	cellobiose catabolism							jl	2011-07-28T01:35:38Z					biological_process											owl:Class	
GO:2000840	biolink:NamedThing	regulation of dehydroepiandrosterone secretion	Any process that modulates the frequency, rate or extent of dehydroepiandrosterone secretion.	tmpzr1t_l9r_go_relaxed.owl	regulation of dehydroisoandrosterone secretion|regulation of DHEA secretion|regulation of 3beta-hydroxyandrost-5-en-17-one secretion							bf	2011-07-26T08:41:29Z					biological_process											owl:Class	
GO:0035942	biolink:NamedThing	dehydroepiandrosterone secretion	The regulated release of dehydroepiandrosterone (3beta-hydroxyandrost-5-en-17-one) into the circulatory system.	tmpzr1t_l9r_go_relaxed.owl	dehydroisoandrosterone secretion|DHEA secretion|3beta-hydroxyandrost-5-en-17-one secretion							bf	2011-07-25T02:13:54Z					biological_process											owl:Class	
GO:0021559	biolink:NamedThing	trigeminal nerve development	The process whose specific outcome is the progression of the trigeminal nerve over time, from its formation to the mature structure. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains sensory branches that reach the pterygopalatine fossa via the inferior orbital fissure (face, cheek and upper teeth) and pterygopalatine canal (soft and hard palate, nasal cavity and pharynx). The motor part of the mandibular branch is distributed to the muscles of mastication, the mylohyoid muscle and the anterior belly of the digastric. The mandibular nerve also innervates the tensor veli palatini and tensor tympani muscles. The sensory part of the mandibular nerve is composed of branches that carry general sensory information from the mucous membranes of the mouth and cheek, anterior two-thirds of the tongue, lower teeth, skin of the lower jaw, side of the head and scalp and meninges of the anterior and middle cranial fossae.	tmpzr1t_l9r_go_relaxed.owl	cranial nerve 5 development|cranial nerve V development|CN V development													biological_process											owl:Class	
GO:0120169	biolink:NamedThing	detection of cold stimulus involved in thermoception	The series of events in which a cold stimulus is received and converted into a molecular signal as part of thermoception.	tmpzr1t_l9r_go_relaxed.owl	sensory detection of cold stimulus during thermoception|thermoception, sensory transduction of cold stimulus|thermoception, sensory detection of cold stimulus|sensory transduction of cold stimulus during thermoception							krc	2018-05-21T20:36:05Z					biological_process											owl:Class	
GO:0062035	biolink:NamedThing	sensory perception of cold stimulus	The series of events required for an organism to receive a cold temperature stimulus, convert it to a molecular signal, and recognize and characterize the signal.	tmpzr1t_l9r_go_relaxed.owl								dph	2018-04-30T13:48:10Z					biological_process											owl:Class	
GO:0050655	biolink:NamedThing	dermatan sulfate proteoglycan metabolic process	The chemical reactions and pathways involving dermatan sulfate proteoglycan, any glycoprotein whose glycosaminoglycan units are dermatan sulfate (chondroitin sulfate B). Dermatan sulfate is a glycosaminoglycan with repeats consisting of beta-(1,4)-linked L-iduronyl-beta-(1,3)-N-acetyl-D-galactosamine 4-sulfate units.	tmpzr1t_l9r_go_relaxed.owl	chondroitin sulfate B proteoglycan metabolic process|dermatan sulphate proteoglycan metabolism|dermatan sulfate proteoglycan metabolism|chondroitin sulfate B proteoglycan metabolism|dermatan sulphate proteoglycan metabolic process													biological_process											owl:Class	
GO:1990063	biolink:NamedThing	Bam protein complex	Protein complex which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. In E. coli it is composed of BamABCDE, of the outer membrane protein BamA, and four lipoproteins BamB, BamC, BamD and BamE. BamA interacts directly with BamB and the BamCDE subcomplex.	tmpzr1t_l9r_go_relaxed.owl	OMP complex							bhm	2013-03-20T15:42:57Z					cellular_component											owl:Class	
GO:2001255	biolink:NamedThing	positive regulation of histone H3-K36 trimethylation	Any process that activates or increases the frequency, rate or extent of histone H3-K36 trimethylation.	tmpzr1t_l9r_go_relaxed.owl								pr	2011-12-06T07:38:24Z					biological_process											owl:Class	
GO:0003413	biolink:NamedThing	chondrocyte differentiation involved in endochondral bone morphogenesis	The process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte that will contribute to the development of a bone. A chondrocyte is a polymorphic cell that forms cartilage.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-12-22T08:39:58Z					biological_process											owl:Class	
GO:0012506	biolink:NamedThing	vesicle membrane	The lipid bilayer surrounding any membrane-bounded vesicle in the cell.	tmpzr1t_l9r_go_relaxed.owl					NIF_Subcellular:sao1153182838									cellular_component											owl:Class	
GO:1903980	biolink:NamedThing	positive regulation of microglial cell activation	Any process that activates or increases the frequency, rate or extent of microglial cell activation.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of microglial cell activation|up regulation of microglial cell activation|upregulation of microglial cell activation|activation of microglial cell activation							nc	2015-03-02T15:17:44Z					biological_process											owl:Class	
GO:0001774	biolink:NamedThing	microglial cell activation	The change in morphology and behavior of a microglial cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0048933	biolink:NamedThing	afferent axon development in posterior lateral line nerve	The process whose specific outcome is the progression of an afferent axon in the posterior lateral line nerve over time from its formation to the mature structure. This process includes axonogenesis and pathfinding of the afferent axons in the posterior lateral line nerve.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0072255	biolink:NamedThing	metanephric glomerular mesangial cell development	The process whose specific outcome is the progression of a glomerular mesangial cell in the metanephros over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-03-19T04:06:58Z					biological_process											owl:Class	
GO:0048195	biolink:NamedThing	Golgi membrane priming complex assembly	The aggregation, arrangement and bonding together of a set of components to form a membrane priming complex. An incoming coat component recognizes both GTPase and a membrane protein to form the priming complex.	tmpzr1t_l9r_go_relaxed.owl	formation of dictyosome membrane priming complex|formation of Golgi membrane priming complex													biological_process											owl:Class	
GO:0098564	biolink:NamedThing	trans-Golgi network transport vesicle lumen	The volume enclosed within the membrane of a trans-Golgi network transport vesicle.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0007561	biolink:NamedThing	imaginal disc eversion	The eversion (turning inside out) of imaginal discs from their peripodial sacs, resulting in movement of the epithelium to the outside of the larval epidermis.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1903996	biolink:NamedThing	negative regulation of non-membrane spanning protein tyrosine kinase activity	Any process that stops, prevents or reduces the frequency, rate or extent of non-membrane spanning protein tyrosine kinase activity.	tmpzr1t_l9r_go_relaxed.owl	down regulation of p60c-src protein tyrosine kinase activity|negative regulation of janus kinase 2 activity|downregulation of janus kinase 1 activity|negative regulation of Bruton's tyrosine kinase activity|down-regulation of Bruton's tyrosine kinase activity|down-regulation of janus kinase 3 activity|inhibition of non-specific protein-tyrosine kinase activity|negative regulation of p60c-src protein tyrosine kinase activity|negative regulation of non-specific protein-tyrosine kinase activity|down regulation of focal adhesion kinase activity|inhibition of janus kinase 3 activity|downregulation of focal adhesion kinase activity|down regulation of janus kinase 2 activity|down-regulation of ATP:protein-L-tyrosine O-phosphotransferase (non-specific) activity|downregulation of non-membrane spanning protein tyrosine kinase activity|downregulation of janus kinase 3 activity|negative regulation of focal adhesion kinase activity|down regulation of janus kinase 3 activity|down regulation of ATP:protein-L-tyrosine O-phosphotransferase (non-specific) activity|down-regulation of non-membrane spanning protein tyrosine kinase activity|down-regulation of janus kinase 1 activity|downregulation of ATP:protein-L-tyrosine O-phosphotransferase (non-specific) activity|inhibition of ATP:protein-L-tyrosine O-phosphotransferase (non-specific) activity|down regulation of non-specific protein-tyrosine kinase activity|negative regulation of ATP:protein-L-tyrosine O-phosphotransferase (non-specific) activity|negative regulation of cytoplasmic protein tyrosine kinase activity|down regulation of janus kinase 1 activity|downregulation of janus kinase 2 activity|negative regulation of janus kinase 1 activity|inhibition of cytoplasmic protein tyrosine kinase activity|down-regulation of non-specific protein-tyrosine kinase activity|inhibition of Bruton's tyrosine kinase activity|inhibition of janus kinase 1 activity|down-regulation of janus kinase 2 activity|down regulation of Bruton's tyrosine kinase activity|downregulation of non-specific protein-tyrosine kinase activity|down regulation of cytoplasmic protein tyrosine kinase activity|downregulation of p60c-src protein tyrosine kinase activity|downregulation of Bruton's tyrosine kinase activity|inhibition of focal adhesion kinase activity|down-regulation of cytoplasmic protein tyrosine kinase activity|down-regulation of focal adhesion kinase activity|down-regulation of p60c-src protein tyrosine kinase activity|down regulation of non-membrane spanning protein tyrosine kinase activity|inhibition of p60c-src protein tyrosine kinase activity|inhibition of janus kinase 2 activity|downregulation of cytoplasmic protein tyrosine kinase activity|negative regulation of janus kinase 3 activity|inhibition of non-membrane spanning protein tyrosine kinase activity							nc	2015-03-05T16:34:41Z					biological_process											owl:Class	
GO:0031392	biolink:NamedThing	regulation of prostaglandin biosynthetic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of prostaglandin.	tmpzr1t_l9r_go_relaxed.owl	regulation of prostaglandin anabolism|regulation of prostaglandin formation|regulation of prostaglandin synthesis|regulation of prostaglandin biosynthesis													biological_process											owl:Class	
GO:0001516	biolink:NamedThing	prostaglandin biosynthetic process	The chemical reactions and pathways resulting in the formation of prostaglandins, any of a group of biologically active metabolites which contain a cyclopentane ring.	tmpzr1t_l9r_go_relaxed.owl	prostaglandin anabolism|prostaglandin biosynthesis|prostaglandin formation|prostaglandin synthesis													biological_process											owl:Class	
GO:0036479	biolink:NamedThing	peroxidase inhibitor activity	Binds to and stops, prevents or reduces the activity of peroxidase.	tmpzr1t_l9r_go_relaxed.owl						GO:0036479 is reserved for cases when the inhibitor directly interacts with the peroxidase. When inhibition of peroxidase activity is achieved without enzyme binding, or when the mechanism of regulation is unknown, instead annotate to 'negative regulation of peroxidase activity ; GO:2000469'.		bf	2014-07-24T10:14:45Z					molecular_function											owl:Class	
GO:0140631	biolink:NamedThing	aldehyde dehydrogenase (NAD+) inhibitor activity	Binds to and stops, prevents or reduces the activity of aldehyde dehydrogenase (NAD+).	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/21265						pg	2021-04-09T09:40:21Z					molecular_function											owl:Class	
GO:0034672	biolink:NamedThing	anterior/posterior pattern specification involved in pronephros development	The developmental process that results in the creation of defined areas or spaces within the pronephros along the anterior/posterior axis to which cells respond and eventually are instructed to differentiate.	tmpzr1t_l9r_go_relaxed.owl	anterior/posterior pattern specification involved in pronephric kidney development													biological_process											owl:Class	
GO:0032260	biolink:NamedThing	response to jasmonic acid stimulus involved in jasmonic acid and ethylene-dependent systemic resistance	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a jasmonic acid stimulus received in the context of the jasmonic acid- and ethylene (ethene)-dependent process that confers broad spectrum systemic resistance to disease in response to wounding or a pathogen.	tmpzr1t_l9r_go_relaxed.owl	response to jasmonic acid stimulus during jasmonic acid and ethylene-dependent systemic resistance													biological_process											owl:Class	
GO:0043162	biolink:NamedThing	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway	The chemical reactions and pathways resulting in the breakdown of a protein or peptide covalently tagged with ubiquitin, via the multivesicular body (MVB) sorting pathway; ubiquitin-tagged proteins are sorted into MVBs, and delivered to a lysosome/vacuole for degradation.	tmpzr1t_l9r_go_relaxed.owl	ubiquitin-dependent protein catabolism via the MVB pathway|ubiquitin-dependent protein catabolic process via the MVB pathway|ubiquitin-dependent protein breakdown via the multivesicular body pathway|ubiquitin-dependent protein degradation via the multivesicular body pathway													biological_process											owl:Class	
GO:0014016	biolink:NamedThing	neuroblast differentiation	The process in which a relatively unspecialized cell acquires specialized features of a neuroblast. There are at least four stages through which the pluripotent cells of epiblast or blastula become neuroblasts.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0002406	biolink:NamedThing	antigen sampling by M cells in mucosal-associated lymphoid tissue	The process of antigen samples carried out by M cells in the mucosal-associated lymphoid tissue.	tmpzr1t_l9r_go_relaxed.owl	antigen sampling by M cells in MALT													biological_process											owl:Class	
GO:0048641	biolink:NamedThing	regulation of skeletal muscle tissue development	Any process that modulates the frequency, rate or extent of skeletal muscle tissue development.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0016204	biolink:NamedThing	determination of muscle attachment site	The process that mediates the transfer of information from the cells of a muscle to those of its intended target, thereby identifying the target site.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0016203	biolink:NamedThing	muscle attachment	The developmental process in which a skeletal muscle attaches to its target (such as bone or body wall).	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0034551	biolink:NamedThing	mitochondrial respiratory chain complex III assembly	The aggregation, arrangement and bonding together of a set of components to form the cytochrome bc(1) complex (also known as ubiquinol-cytochrome c reductase), in the mitochondrial inner membrane.	tmpzr1t_l9r_go_relaxed.owl	mitochondrial cytochrome bc(1) complex assembly													biological_process											owl:Class	
GO:0003066	biolink:NamedThing	positive regulation of heart rate by norepinephrine	The process in which the secretion of norepinephrine into the bloodstream or released from nerve endings increases the rate of heart muscle contraction.	tmpzr1t_l9r_go_relaxed.owl	norepinephrine cardiac chronotropy|noradrenaline cardiac chronotropy|noradrenaline regulation of the rate of heart muscle contraction|positive regulation of heart contraction rate by norepinephrine|positive regulation of heart rate by adrenaline													biological_process											owl:Class	
GO:0005125	biolink:NamedThing	cytokine activity	The activity of a soluble extracellular gene product that interacts with a receptor to effect a change in the activity of the receptor to control the survival, growth, differentiation and effector function of tissues and cells.	tmpzr1t_l9r_go_relaxed.owl	paracrine activity|autocrine activity	https://github.com/geneontology/go-ontology/issues/19116												molecular_function											owl:Class	
GO:1902944	biolink:NamedThing	aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process	Any aspartic-type endopeptidase activity that is involved in amyloid precursor protein catabolic process.	tmpzr1t_l9r_go_relaxed.owl	aspartic endopeptidase activity involved in amyloid precursor protein breakdown|aspartic endopeptidase activity involved in amyloid precursor protein catabolism|aspartic endopeptidase activity involved in APP catabolic process|carboxyl protease activity involved in APP catabolism|aspartate protease activity involved in amyloid precursor protein catabolism|aspartyl protease activity involved in APP catabolism|aspartyl protease activity involved in amyloid precursor protein breakdown|aspartic endopeptidase activity involved in amyloid precursor protein degradation|carboxyl protease activity involved in APP catabolic process|aspartic-type endopeptidase activity involved in amyloid precursor protein breakdown|aspartic protease activity involved in amyloid precursor protein breakdown|carboxyl protease activity involved in amyloid precursor protein breakdown|aspartic endopeptidase activity involved in amyloid precursor protein catabolic process|carboxyl protease activity involved in amyloid precursor protein catabolism|aspartate protease activity involved in APP catabolism|aspartic protease activity involved in amyloid precursor protein degradation|aspartic-type endopeptidase activity involved in amyloid precursor protein catabolism|aspartic protease activity involved in APP catabolic process|aspartyl protease activity involved in amyloid precursor protein catabolism|aspartic protease activity involved in amyloid precursor protein catabolic process|aspartate protease activity involved in APP catabolic process|aspartic protease activity involved in amyloid precursor protein catabolism|aspartic-type endopeptidase activity involved in APP catabolic process|carboxyl protease activity involved in amyloid precursor protein degradation|aspartic protease activity involved in APP catabolism|aspartic endopeptidase activity involved in APP catabolism|carboxyl protease activity involved in amyloid precursor protein catabolic process|aspartic-type endopeptidase activity involved in APP catabolism|aspartate protease activity involved in amyloid precursor protein breakdown|aspartyl protease activity involved in APP catabolic process|aspartyl protease activity involved in amyloid precursor protein catabolic process|aspartate protease activity involved in amyloid precursor protein catabolic process|aspartyl protease activity involved in amyloid precursor protein degradation|aspartic-type endopeptidase activity involved in amyloid precursor protein degradation|aspartate protease activity involved in amyloid precursor protein degradation							sjp	2014-05-02T07:59:42Z					molecular_function											owl:Class	
GO:0050953	biolink:NamedThing	sensory perception of light stimulus	The series of events required for an organism to receive a sensory light stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0043402	biolink:NamedThing	glucocorticoid mediated signaling pathway	A series of molecular signals mediated by the detection of a glucocorticoid hormone.	tmpzr1t_l9r_go_relaxed.owl	glucocorticoid mediated signalling													biological_process											owl:Class	
GO:0110150	biolink:NamedThing	negative regulation of biomineralization	Any process that stops, prevents, or reduces the frequency, rate or extent of biomineralization, the formation and deposition of mineral crystals by living organisms.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of mineralisation|negative regulation of mineralization|negative regulation of biomineralisation|negative regulation of biomineral formation							kmv	2019-06-10T18:12:24Z					biological_process											owl:Class	
GO:0021817	biolink:NamedThing	nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration	The microtubule-mediated movement of the nucleus that is required for the movement of cells along radial glial fibers as a component of the process of cerebral cortex glial-mediated radial cell migration.	tmpzr1t_l9r_go_relaxed.owl	nucleokinesis involved in cell locomotion in cerebral cortex radial glia guided migration|nucleokinesis involved in cell locomotion in cerebral cortex glial-mediated radial migration													biological_process											owl:Class	
GO:1905059	biolink:NamedThing	P-type calcium transporter activity involved in regulation of postsynaptic cytosolic calcium ion concentration	A calcium-transporting P-type ATPase activity involved in regulation of postsynaptic cytosolic calcium ion concentration.	tmpzr1t_l9r_go_relaxed.owl	plasma membrane Ca-ATPase involved in regulation of postsynaptic cytosolic calcium ion concentration|ATPase-coupled calcium ion transmembrane transporter activity involved in regulation of postsynaptic cytosolic calcium levels|calcium ABC transporter involved in regulation of postsynaptic cytosolic calcium ion concentration|sarcoplasmic reticulum ATPase involved in regulation of postsynaptic cytosolic calcium ion concentration|Ca(2+)-transporting ATPase activity involved in regulation of postsynaptic cytosolic calcium ion concentration|ATP phosphohydrolase (Ca2+-transporting) involved in regulation of postsynaptic cytosolic calcium ion concentration|Ca2+-pumping ATPase activity involved in regulation of postsynaptic cytosolic calcium ion concentration|Ca2+-transporting ATPase activity involved in regulation of postsynaptic cytosolic calcium ion concentration|calcium efflux ATPase involved in regulation of postsynaptic cytosolic calcium ion concentration|sarco(endo)plasmic reticulum Ca2+-ATPase involved in regulation of postsynaptic cytosolic calcium ion concentration|calcium-transporting ATPase activity involved in regulation of postsynaptic cytosolic calcium ion concentration|calcium transporting ATPase activity involved in regulation of postsynaptic cytosolic calcium ion concentration|calcium-translocating P-type ATPase activity involved in regulation of postsynaptic cytosolic calcium ion concentration|calcium-transporting ATPase activity involved in regulation of postsynaptic cytosolic calcium levels							dos	2016-03-18T12:32:08Z					molecular_function											owl:Class	
GO:0003361	biolink:NamedThing	noradrenergic neuron differentiation involved in brainstem development	The process in which a relatively unspecialized cell acquires specialized features of an noradrenergic neuron that is part of the brainstem.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-12-03T10:53:30Z					biological_process											owl:Class	
GO:0061028	biolink:NamedThing	establishment of endothelial barrier	The establishment of a barrier between endothelial cell layers, such as those in the brain, lung or intestine, to exert specific and selective control over the passage of water and solutes, thus allowing formation and maintenance of compartments that differ in fluid and solute composition.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-02-09T09:26:59Z					biological_process											owl:Class	
GO:0008428	biolink:NamedThing	ribonuclease inhibitor activity	Binds to and stops, prevents or reduces the activity of ribonuclease.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0007078	biolink:NamedThing	lamin depolymerization	The cell cycle process in which lamin is depolymerized.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:2000269	biolink:NamedThing	regulation of fibroblast apoptotic process	Any process that modulates the frequency, rate or extent of fibroblast apoptotic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of fibroblast apoptosis							jl	2010-11-23T01:07:23Z					biological_process											owl:Class	
GO:0044346	biolink:NamedThing	fibroblast apoptotic process	Any apoptotic process in a fibroblast, a connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules.	tmpzr1t_l9r_go_relaxed.owl	fibroblast apoptosis							jl	2010-09-23T11:33:38Z					biological_process											owl:Class	
GO:0040025	biolink:NamedThing	vulval development	The process whose specific outcome is the progression of the egg-laying organ of female and hermaphrodite nematodes over time, from its formation to the mature structure. In nematodes, the vulva is formed from ventral epidermal cells during larval stages to give rise to a fully formed vulva in the adult.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1902268	biolink:NamedThing	negative regulation of polyamine transmembrane transport	Any process that stops, prevents or reduces the frequency, rate or extent of polyamine transmembrane transport.	tmpzr1t_l9r_go_relaxed.owl	down regulation of polyamine transmembrane transport|downregulation of polyamine transmembrane transport|inhibition of polyamine transmembrane transport|down-regulation of polyamine transmembrane transport							mcc	2013-06-28T21:34:42Z					biological_process											owl:Class	
GO:1990926	biolink:NamedThing	short-term synaptic potentiation	The process by which synaptic transmission, induced by the arrival of a spike (action potential) at a synapse, acts to increase the amount of neurotransmitter released in response to the arrival of subsequent spikes.  This effect is seen when a train of closely space spikes arrives at a synapse with a low initial release probability.  It occurs in a timeframe of tens to hundreds of milliseconds.	tmpzr1t_l9r_go_relaxed.owl	synaptic facilitation					The mechanism of short term potentiation is thought to be either increased influx of calcium into the presynapse (Zucker and Regeh, 2002 PMID:11826273) increased sensitivity to calcium (Jackman et al., 2016 PMID:26738595) or both.		sp	2016-02-12T13:17:18Z					biological_process											owl:Class	
GO:0071517	biolink:NamedThing	maintenance of imprinting at mating-type locus	Any process involved in preserving the structure of a stable single-strand DNA lesion that triggers programmed gene conversion at the mating-type locus, thereby restricting mating-type interconversion to one of the two sister chromatids during DNA replication.	tmpzr1t_l9r_go_relaxed.owl	mating type determination, maintenance of imprinting							mah	2010-01-06T01:17:05Z					biological_process											owl:Class	
GO:1903371	biolink:NamedThing	regulation of endoplasmic reticulum tubular network organization	Any process that modulates the frequency, rate or extent of endoplasmic reticulum tubular network organization.	tmpzr1t_l9r_go_relaxed.owl	regulation of endoplasmic reticulum tubular network organisation|regulation of ER tubular network organization|regulation of ER tubular network organisation							als	2014-08-22T11:01:14Z					biological_process											owl:Class	
GO:0072124	biolink:NamedThing	regulation of glomerular mesangial cell proliferation	Any process that modulates the frequency, rate or extent of glomerular mesangial cell proliferation.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-02-22T01:46:12Z					biological_process											owl:Class	
GO:0000312	biolink:NamedThing	plastid small ribosomal subunit	The smaller of the two subunits of a plastid ribosome.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:1903348	biolink:NamedThing	positive regulation of bicellular tight junction assembly	Any process that activates or increases the frequency, rate or extent of tight junction assembly.	tmpzr1t_l9r_go_relaxed.owl	upregulation of tight junction formation|activation of tight junction formation|activation of tight junction assembly|positive regulation of tight junction formation|up-regulation of tight junction formation|up regulation of tight junction formation|up regulation of tight junction assembly|up-regulation of tight junction assembly|upregulation of tight junction assembly							pr	2014-08-19T11:05:06Z					biological_process											owl:Class	
GO:0001746	biolink:NamedThing	Bolwig's organ morphogenesis	The morphogenetic process in which the anatomical structures of the larval eye in Drosophila are generated and organized. The larval eye in Drosophila is a relatively simple sensory system composed of Bolwig's organs: two clusters, each composed of 12 photoreceptor cells from which axons extend in a single fascicle to the brain.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0055034	biolink:NamedThing	Bolwig's organ development	The process whose specific outcome is the progression of the Bolwig's organ over time, from its formation to the mature structure. The larval eye in Drosophila is a relatively simple sensory system composed of Bolwig's organs: two clusters, each composed of 12 photoreceptor cells from which axons extend in a single fascicle to the brain.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0000801	biolink:NamedThing	central element	A structural unit of the synaptonemal complex found between the lateral elements.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0061254	biolink:NamedThing	mesonephric glomerular parietal epithelial cell development	The process whose specific outcome is the progression of a mesonephric glomerular parietal epithelial cell over time, from its formation to the mature structure. Mesonephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-08-30T01:30:36Z					biological_process											owl:Class	
GO:0000088	biolink:NamedThing	mitotic prophase	The cell cycle phase which is the first stage of M phase of mitosis and during which chromosomes condense and the two daughter centrioles and their asters migrate toward the poles of the cell.	tmpzr1t_l9r_go_relaxed.owl						Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).								biological_process											owl:Class	
GO:0010709	biolink:NamedThing	heteroduplex formation involved in double-strand break repair via synthesis-dependent strand annealing	The formation of a stable duplex DNA that contains one strand from each of the two recombining DNA molecules resulting in the error-free repair of a double-strand break without the exchange of adjacent sequences.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0046813	biolink:NamedThing	receptor-mediated virion attachment to host cell	The process by which a virion attaches to a host cell by binding to a receptor on the host cell surface.	tmpzr1t_l9r_go_relaxed.owl	virion attachment, binding of host cell surface receptor													biological_process											owl:Class	
GO:1904319	biolink:NamedThing	negative regulation of smooth muscle contraction involved in micturition	Any process that stops, prevents or reduces the frequency, rate or extent of smooth muscle contraction involved in micturition.	tmpzr1t_l9r_go_relaxed.owl	downregulation of urinary bladder smooth muscle contraction involved in micturition|negative regulation of urinary bladder smooth muscle contraction involved in micturition|down regulation of smooth muscle contraction involved in micturition|inhibition of smooth muscle contraction involved in urination|downregulation of smooth muscle contraction involved in urination|inhibition of smooth muscle contraction involved in micturition|down regulation of smooth muscle contraction involved in urination|down-regulation of smooth muscle contraction involved in urination|downregulation of smooth muscle contraction involved in micturition|down-regulation of urinary bladder smooth muscle contraction involved in micturition|negative regulation of smooth muscle contraction involved in urination|inhibition of urinary bladder smooth muscle contraction involved in micturition|down-regulation of smooth muscle contraction involved in micturition|down regulation of urinary bladder smooth muscle contraction involved in micturition							sl	2015-06-10T18:46:17Z					biological_process											owl:Class	
GO:2000841	biolink:NamedThing	negative regulation of dehydroepiandrosterone secretion	Any process that stops, prevents or reduces the frequency, rate or extent of dehydroepiandrosterone secretion.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of 3beta-hydroxyandrost-5-en-17-one secretion|negative regulation of DHEA secretion|negative regulation of dehydroisoandrosterone secretion							bf	2011-07-26T08:41:33Z					biological_process											owl:Class	
GO:0098572	biolink:NamedThing	stromal side of plastid thylakoid membrane	The side (leaflet) of the plastid thylakoid membrane that faces the stroma, and any proteins embedded in it or loosely bound to its surface.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0048354	biolink:NamedThing	mucilage biosynthetic process involved in seed coat development	The chemical reactions and pathways resulting in the formation of mucilage that occur as part of seed coat development; mucilage is normally synthesized during seed coat development.	tmpzr1t_l9r_go_relaxed.owl	mucilage biosynthetic process during seed coat development|mucilage synthesis during seed coat development|mucilage anabolism during seed coat development|mucilage formation during seed coat development													biological_process											owl:Class	
GO:0048366	biolink:NamedThing	leaf development	The process whose specific outcome is the progression of the leaf over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0034383	biolink:NamedThing	low-density lipoprotein particle clearance	The process in which a low-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.	tmpzr1t_l9r_go_relaxed.owl	LDL clearance													biological_process											owl:Class	
GO:0090495	biolink:NamedThing	low-density lipoprotein particle disassembly	The disaggregation of a low-density lipoprotein particle into its constituent components.	tmpzr1t_l9r_go_relaxed.owl								tb	2012-10-17T11:48:56Z					biological_process											owl:Class	
GO:0007542	biolink:NamedThing	primary sex determination, germ-line	The transmission of information about sexual status, from the initial general determination, to signals specific to the germ-line.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0090133	biolink:NamedThing	mesendoderm migration	The process in which the population of cells that make up a mesendoderm undergo directed movement. The mesendoderm is the epithelial tissue that gives rise to both mesoderm and endoderm.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-12-07T03:22:08Z					biological_process											owl:Class	
GO:0034507	biolink:NamedThing	chromosome, centromeric outer repeat region	The portion of the centromeric region of a chromosome that flanks the core region, encompassing repeated regions of a chromosome centromere and the proteins that bind to it.	tmpzr1t_l9r_go_relaxed.owl	chromosome, centric outer repeat region													cellular_component											owl:Class	
GO:1990688	biolink:NamedThing	Golgi vesicle fusion with endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane	The joining of the lipid bilayer membrane around a Golgi vesicle to the lipid bilayer membrane of the ERGIC. Such vesicles include COPI-coated transport vesicles involved in retrograde transport.	tmpzr1t_l9r_go_relaxed.owl	Golgi vesicle fusion with ER-Golgi intermediate compartment membrane|Golgi vesicle fusion with ERGIC membrane							bhm	2015-03-12T09:34:21Z					biological_process											owl:Class	
GO:0044207	biolink:NamedThing	translation initiation ternary complex	A ribonucleoprotein complex that contains aminoacylated initiator methionine tRNA, GTP, and initiation factor 2 (either eIF2 in eukaryotes, or IF2 in prokaryotes). In prokaryotes, fMet-tRNA (initiator) is used rather than Met-tRNA (initiator).	tmpzr1t_l9r_go_relaxed.owl	Met-tRNA/eIF2.GTP ternary complex|translation initiation (ternary) complex							jl	2009-10-22T02:38:55Z					cellular_component											owl:Class	
GO:0030293	biolink:NamedThing	transmembrane receptor protein tyrosine kinase inhibitor activity	Binds to and stops, prevents or reduces the activity of a transmembrane receptor protein tyrosine kinase.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0062247	biolink:NamedThing	chloroplast vesicle	A intracellular vesicle that is part of a chloroplast.	tmpzr1t_l9r_go_relaxed.owl								dph	2020-05-01T12:10:16Z					cellular_component											owl:Class	
GO:0060254	biolink:NamedThing	regulation of N-terminal protein palmitoylation	Any process that modulates the rate frequency or extent of the covalent attachment of a palmitoyl group to the N-terminal amino acid residue of a protein.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0001669	biolink:NamedThing	acrosomal vesicle	A structure in the head of a spermatozoon that contains acid hydrolases, and is concerned with the breakdown of the outer membrane of the ovum during fertilization. It lies just beneath the plasma membrane and is derived from the lysosome.	tmpzr1t_l9r_go_relaxed.owl	acrosomal granule|acrosome				Wikipedia:Acrosome									cellular_component											owl:Class	
GO:0008526	biolink:NamedThing	phosphatidylinositol transfer activity	Removes phosphatidylinositol from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle.	tmpzr1t_l9r_go_relaxed.owl	intermembrane phosphotidylinositol transfer activity|phosphatidylinositol carrier activity|phosphatidylinositol transporter activity|intermembrane phosphatidylinositol transfer activity				Reactome:R-HSA-8869241|Reactome:R-HSA-8874470			krc	2017-03-17T04:22:47Z			GO:0120018		molecular_function											owl:Class	
GO:0021784	biolink:NamedThing	postganglionic parasympathetic fiber development	The process whose specific outcome is the progression of the postganglionic portion of the parasympathetic fiber over time, from its formation to the mature structure. The parasympathetic fiber is one of the two divisions of the vertebrate autonomic nervous system. Parasympathetic nerves emerge cranially as pre ganglionic fibers from oculomotor, facial, glossopharyngeal and vagus and from the sacral region of the spinal cord. Most neurons are cholinergic and responses are mediated by muscarinic receptors. The parasympathetic system innervates, for example: salivary glands, thoracic and abdominal viscera, bladder and genitalia.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0048486	biolink:NamedThing	parasympathetic nervous system development	The process whose specific outcome is the progression of the parasympathetic nervous system over time, from its formation to the mature structure. The parasympathetic nervous system is one of the two divisions of the vertebrate autonomic nervous system. Parasympathetic nerves emerge cranially as pre ganglionic fibers from oculomotor, facial, glossopharyngeal and vagus and from the sacral region of the spinal cord. Most neurons are cholinergic and responses are mediated by muscarinic receptors. The parasympathetic system innervates, for example: salivary glands, thoracic and abdominal viscera, bladder and genitalia.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0061681	biolink:NamedThing	Entner-Doudoroff pathway through gluconate to D-glyceraldehyde-3-phosphate	The Entner-Doudoroff pathway that proceeds through a D-gluconate intermediate and yields pyruvate and D-glyceraldehyde-3-phosphate.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:ENTNER-DOUDOROFF-PWY-III			dph	2015-01-22T08:55:22Z					biological_process											owl:Class	
GO:0015132	biolink:NamedThing	prostaglandin transmembrane transporter activity	Enables the transfer of prostaglandins from one side of a membrane to the other. A prostaglandin is any of a group of biologically active metabolites which contain a cyclopentane ring due to the formation of a bond between two carbons of a fatty acid. They have a wide range of biological activities.	tmpzr1t_l9r_go_relaxed.owl	prostaglandin/thromboxane transporter activity				Reactome:R-HSA-5661188|Reactome:R-HSA-879528									molecular_function											owl:Class	
GO:0075299	biolink:NamedThing	positive regulation of zygospore formation	Any process that activates, maintains or increases the frequency, rate or extent of frequency, rate or extent of zygospore formation, a process in which a thick-walled spore of some algae and fungi is formed by union of two similar sexual cells, usually serves as a resting spore, and produces the sporophytic phase.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0043001	biolink:NamedThing	Golgi to plasma membrane protein transport	The directed movement of proteins from the Golgi to the plasma membrane in transport vesicles that move from the trans-Golgi network to the plasma membrane.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1990207	biolink:NamedThing	EmrE multidrug transporter complex	A transmembrane protein complex capable of transporting positively charged hydrophobic drugs across the plasma membrane thereby involved in conferring resistance to a wide range of toxic compounds (e.g. methyl viologen, ethidium bromide and acriflavine). It is commonly found in bacteria. In E. coli it forms a homodimer.	tmpzr1t_l9r_go_relaxed.owl	EmrE complex							bhm	2013-10-08T08:37:52Z					cellular_component											owl:Class	
GO:0044592	biolink:NamedThing	response to pullulan	A process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of pullulan stimulus.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-04-26T03:59:06Z					biological_process											owl:Class	
GO:1905586	biolink:NamedThing	negative regulation of outer hair cell apoptotic process	Any process that stops, prevents or reduces the frequency, rate or extent of outer hair cell apoptotic process.	tmpzr1t_l9r_go_relaxed.owl	inhibition of cochlear outer hair cell apoptosis|down-regulation of cochlear outer hair cell apoptotic process|negative regulation of cochlear outer hair cell apoptotic process|downregulation of cochlear outer hair cell apoptosis|down regulation of cochlear outer hair cell apoptotic process|down-regulation of cochlear outer hair cell apoptosis|inhibition of outer hair cell apoptosis|down regulation of outer hair cell apoptosis|inhibition of cochlear outer hair cell apoptotic process|inhibition of outer hair cell apoptotic process|down-regulation of outer hair cell apoptotic process|downregulation of outer hair cell apoptotic process|downregulation of cochlear outer hair cell apoptotic process|downregulation of outer hair cell apoptosis|down regulation of outer hair cell apoptotic process|negative regulation of cochlear outer hair cell apoptosis|down-regulation of outer hair cell apoptosis|negative regulation of outer hair cell apoptosis|down regulation of cochlear outer hair cell apoptosis							sl	2016-10-24T22:35:43Z					biological_process											owl:Class	
GO:1905584	biolink:NamedThing	outer hair cell apoptotic process	Any apoptotic process in an outer hair cell.	tmpzr1t_l9r_go_relaxed.owl	cochlear outer hair cell apoptotic process|outer hair cell apoptosis|cochlear outer hair cell apoptosis							sl	2016-10-21T22:42:13Z					biological_process											owl:Class	
GO:0043534	biolink:NamedThing	blood vessel endothelial cell migration	The orderly movement of an endothelial cell into the extracellular matrix in order to form new blood vessels during angiogenesis.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0002014	biolink:NamedThing	vasoconstriction of artery involved in ischemic response to lowering of systemic arterial blood pressure	The vasoconstriction that is triggered by vasomotor excitation resulting from the detection of high carbon dioxide levels in the vasomotor center of the central nervous system.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0015823	biolink:NamedThing	phenylalanine transport	The directed movement of phenylalanine, 2-amino-3-phenylpropanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	L-phenylalanine transport													biological_process											owl:Class	
GO:0036418	biolink:NamedThing	intrinsic component of mycolate outer membrane	The component of the mycolate outer membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.	tmpzr1t_l9r_go_relaxed.owl	intrinsic to MOM|intrinsic to mycomembrane|intrinsic to mycolate outer membrane							bf	2013-09-05T20:19:04Z					cellular_component											owl:Class	
GO:0022008	biolink:NamedThing	neurogenesis	Generation of cells within the nervous system.	tmpzr1t_l9r_go_relaxed.owl	nervous system cell generation|neural cell differentiation				Wikipedia:Neurogenesis									biological_process											owl:Class	
GO:0045747	biolink:NamedThing	positive regulation of Notch signaling pathway	Any process that activates or increases the frequency, rate or extent of the Notch signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of Notch signalling pathway|positive regulation of N signalling pathway|positive regulation of N signaling pathway|upregulation of Notch signaling pathway|activation of Notch signaling pathway|stimulation of Notch signaling pathway|up regulation of Notch signaling pathway|up-regulation of Notch signaling pathway													biological_process											owl:Class	
GO:1905030	biolink:NamedThing	voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential	Any voltage-gated ion channel activity that is involved in regulation of postsynaptic membrane potential.	tmpzr1t_l9r_go_relaxed.owl	voltage gated ion channel activity involved in regulation of postsynaptic membrane potential|voltage-gated ion channel activity involved in regulation of post-synaptic membrane potential|voltage-dependent ion channel activity involved in regulation of post-synaptic membrane potential|voltage gated ion channel activity involved in regulation of post-synaptic membrane potential|voltage-dependent ion channel activity involved in regulation of postsynaptic membrane potential							dos	2016-03-04T15:51:54Z					molecular_function											owl:Class	
GO:2000009	biolink:NamedThing	negative regulation of protein localization to cell surface	Any process that stops, prevents, or reduces the frequency, rate or extent of protein localization to the cell surface.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of protein localization at cell surface|negative regulation of protein localisation at cell surface							jl	2010-08-04T01:43:52Z					biological_process											owl:Class	
GO:0034394	biolink:NamedThing	protein localization to cell surface	A process in which a protein is transported to, or maintained in, a location within the external part of the cell wall and/or plasma membrane.	tmpzr1t_l9r_go_relaxed.owl	protein localization at cell surface|protein localisation at cell surface													biological_process											owl:Class	
GO:0072029	biolink:NamedThing	long nephron development	The process whose specific outcome is the progression of a long nephron over time, from its formation to the mature structure. Long nephrons are associated with juxtamedullary glomeruli and extend into the inner medulla.	tmpzr1t_l9r_go_relaxed.owl	juxtamedullary nephron development							mah	2010-01-25T02:49:08Z					biological_process											owl:Class	
GO:0002779	biolink:NamedThing	antibacterial peptide secretion	The regulated release of an antibacterial peptide from a cell or a tissue.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1900404	biolink:NamedThing	positive regulation of DNA repair by positive regulation of transcription from RNA polymerase II promoter	A positive regulation of transcription from RNA polymerase II promoter that results in positive regulation of DNA repair.	tmpzr1t_l9r_go_relaxed.owl	activation of DNA repair by positive regulation of transcription from RNA polymerase II promoter|up-regulation of DNA repair by positive regulation of transcription from RNA polymerase II promoter|upregulation of DNA repair by positive regulation of transcription from RNA polymerase II promoter|stimulation of DNA repair by positive regulation of transcription from RNA polymerase II promoter|up regulation of DNA repair by positive regulation of transcription from RNA polymerase II promoter							mah	2012-04-20T02:45:56Z					biological_process											owl:Class	
GO:0110088	biolink:NamedThing	hippocampal neuron apoptotic process	Any apoptotic process that occurs in a hippocampal neuron.	tmpzr1t_l9r_go_relaxed.owl								kmv	2018-02-13T21:06:23Z					biological_process											owl:Class	
GO:0048459	biolink:NamedThing	floral whorl structural organization	The process that contributes to the act of creating the structural organization of the floral whorl. This process pertains to the physical shaping of a rudimentary structure.	tmpzr1t_l9r_go_relaxed.owl	floral whorl structural organisation											GO:0048416		biological_process											owl:Class	
GO:1905650	biolink:NamedThing	positive regulation of shell calcification	Any process that activates or increases the frequency, rate or extent of shell calcification.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of shell calcification|up regulation of shell calcification|upregulation of shell calcification|activation of shell calcification							pga	2016-11-08T16:24:51Z					biological_process											owl:Class	
GO:0003168	biolink:NamedThing	Purkinje myocyte differentiation	The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a Purkinje myocyte (also known as cardiac Purkinje fiber cell). These cells are specialized cardiomyocytes that receive signals from the bundle of His and innervate the ventricular cardiac muscle.	tmpzr1t_l9r_go_relaxed.owl	cardiac Purkinje fiber cell differentiation							dph	2009-10-01T02:49:54Z					biological_process											owl:Class	
GO:0003165	biolink:NamedThing	Purkinje myocyte development	The process whose specific outcome is the progression of a Purkinje myocyte over time, from its formation to the mature structure. The Purkinje myocyte (also known as cardiac Purkinje fiber) is part of the cardiac conduction system that receives signals from the bundle of His and innervates the ventricular cardiac muscle.	tmpzr1t_l9r_go_relaxed.owl	cardiac Purkinje fiber development							dph	2009-10-01T02:07:50Z					biological_process											owl:Class	
GO:0048466	biolink:NamedThing	androecium development	The process whose specific outcome is the progression of the androecium over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0090312	biolink:NamedThing	positive regulation of protein deacetylation	Any process that increases the rate, frequency, or extent of protein deacetylation, the removal of an acetyl group from a protein amino acid. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of protein amino acid deacetylation							tb	2010-04-14T01:30:45Z					biological_process											owl:Class	
GO:0032765	biolink:NamedThing	positive regulation of mast cell cytokine production	Any process that activates or increases the frequency, rate, or extent of mast cell cytokine production.	tmpzr1t_l9r_go_relaxed.owl	upregulation of mast cell cytokine production|stimulation of mast cell cytokine production|up-regulation of mast cell cytokine production|up regulation of mast cell cytokine production|activation of mast cell cytokine production													biological_process											owl:Class	
GO:0061642	biolink:NamedThing	chemoattraction of axon	The process in which a neuron growth cone is directed to a specific target site in response to an attractive chemical signal.	tmpzr1t_l9r_go_relaxed.owl								dph	2014-08-29T08:21:24Z					biological_process											owl:Class	
GO:0032833	biolink:NamedThing	negative regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response	Any process that stops, prevents, or reduces the frequency, rate or extent of differentiation of CD4-positive, CD25-positive, alpha-beta regulatory T cells as part of an immune response.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation during immune response|negative regulation of CD4-positive, CD25-positive, alpha-beta regulatory T lymphocyte differentiation during immune response|down regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation during immune response|inhibition of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation during immune response|negative regulation of CD4-positive, CD25-positive, alpha-beta regulatory T-lymphocyte differentiation during immune response|downregulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation during immune response|negative regulation of CD4-positive, CD25-positive, alpha-beta regulatory T-cell differentiation during immune response|negative regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation during immune response|negative regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell development involved in immune response					Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.								biological_process											owl:Class	
GO:0051330	biolink:NamedThing	meiotic G1 phase	The cell cycle 'gap' phase which is the interval between the completion of DNA segregation by meiosis and the beginning of DNA synthesis.	tmpzr1t_l9r_go_relaxed.owl	G1 phase of meiotic cell cycle					Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).								biological_process											owl:Class	
GO:2000156	biolink:NamedThing	regulation of retrograde vesicle-mediated transport, Golgi to ER	Any process that modulates the frequency, rate or extent of retrograde vesicle-mediated transport, Golgi to ER.	tmpzr1t_l9r_go_relaxed.owl	regulation of retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum|regulation of cis-Golgi to rough endoplasmic reticulum vesicle-mediated transport|regulation of retrograde (Golgi to ER) transport|regulation of retrograde transport, Golgi to endoplasmic reticulum|regulation of cis-Golgi to rough ER transport|regulation of cis-Golgi to rough ER vesicle-mediated transport|regulation of retrograde transport, Golgi to ER|regulation of cis-Golgi to rough endoplasmic reticulum transport							mah	2010-10-04T12:46:35Z					biological_process											owl:Class	
GO:1901400	biolink:NamedThing	positive regulation of transforming growth factor beta3 activation	Any process that activates or increases the frequency, rate or extent of transforming growth factor beta3 activation.	tmpzr1t_l9r_go_relaxed.owl	upregulation of transforming growth factor beta3 activation|positive regulation of TGF-beta 3 activation|up regulation of transforming growth factor beta3 activation|upregulation of TGF-beta 3 activation|activation of TGFbeta 3 activation|up regulation of TGFbeta 3 activation|activation of transforming growth factor beta3 activation|upregulation of TGFB3 activation|up-regulation of TGF-beta 3 activation|positive regulation of TGFbeta 3 activation|up-regulation of transforming growth factor beta3 activation|upregulation of TGFbeta 3 activation|activation of TGFB3 activation|up-regulation of TGFB3 activation|activation of TGF-beta 3 activation|up-regulation of TGFbeta 3 activation|positive regulation of TGFB3 activation|up regulation of TGFB3 activation|up regulation of TGF-beta 3 activation							bf	2012-10-01T10:50:49Z					biological_process											owl:Class	
GO:0004912	biolink:NamedThing	interleukin-3 receptor activity	Combining with interleukin-3 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	IL-3 receptor activity|IL-3R				Wikipedia:Interleukin-3_receptor									molecular_function											owl:Class	
GO:0097178	biolink:NamedThing	ruffle assembly	The aggregation, arrangement and bonding together of a set of components to form a ruffle, a projection at the leading edge of a crawling cell; the protrusions are supported by a microfilament meshwork. The formation of ruffles (also called membrane ruffling) is thought to be controlled by a group of enzymes known as Rho GTPases, specifically RhoA, Rac1 and cdc42.	tmpzr1t_l9r_go_relaxed.owl	membrane ruffle formation|membrane ruffling							pr	2011-10-16T01:46:09Z					biological_process											owl:Class	
GO:0030073	biolink:NamedThing	insulin secretion	The regulated release of proinsulin from secretory granules accompanied by cleavage of proinsulin to form mature insulin. In vertebrates, insulin is secreted from B granules in the B cells of the vertebrate pancreas and from insulin-producing cells in insects.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/11255#issuecomment-426191045												biological_process											owl:Class	
GO:0061547	biolink:NamedThing	glycogen synthase activity, transferring glucose-1-phosphate	Catalysis of the reaction: UDP-glucose + (1,4)-alpha-D-glucosyl(n) = UMP + (1,4)-alpha-D-glucosyl(n)-glucose-1-phosphate.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-3781024|Reactome:R-HSA-3780994			dph	2013-07-02T09:59:18Z					molecular_function											owl:Class	
GO:0030343	biolink:NamedThing	vitamin D3 25-hydroxylase activity	Catalysis of the reaction: vitamin D3 + NADPH + H+ + O2 = calcidiol + NADP+ + H2O.	tmpzr1t_l9r_go_relaxed.owl	cholecalciferol 25-hydroxylase activity				Reactome:R-HSA-209845|Reactome:R-HSA-5602147|MetaCyc:RXN-9829|RHEA:32903									molecular_function											owl:Class	
GO:0035729	biolink:NamedThing	cellular response to hepatocyte growth factor stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hepatocyte growth factor stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to HGF stimulus							bf	2011-03-10T03:04:19Z					biological_process											owl:Class	
GO:0036508	biolink:NamedThing	protein alpha-1,2-demannosylation	The removal of one or more alpha 1,2-linked mannose residues from a mannosylated protein.	tmpzr1t_l9r_go_relaxed.owl	mannose trimming|glycoprotein mannose trimming					Consider also annotating to 'mannosyl-oligosaccharide 1,2-alpha-mannosidase activity ; GO:0004571'.		bf	2015-06-11T13:58:50Z					biological_process											owl:Class	
GO:0004571	biolink:NamedThing	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity	Catalysis of the hydrolysis of the terminal (1->2)-linked alpha-D-mannose residues in an oligo-mannose oligosaccharide.	tmpzr1t_l9r_go_relaxed.owl	mannosidase I|exo-alpha-1,2-mannanase activity|mannose-9 processing alpha-mannosidase activity|ManI activity|mannosidase 1A activity|Man9-mannosidase activity|1,2-alpha-mannosyl-oligosaccharide alpha-D-mannohydrolase activity|1,2-alpha-mannosidase|glycoprotein processing mannosidase I|mannosidase 1B activity				Reactome:R-HSA-964830|Reactome:R-HSA-901036|Reactome:R-HSA-6782685|Reactome:R-HSA-964737|Reactome:R-HSA-901024|EC:3.2.1.113|Reactome:R-HSA-901074|Reactome:R-HSA-9696807|Reactome:R-HSA-9036008|KEGG_REACTION:R05982|Reactome:R-HSA-964825|Reactome:R-HSA-4793949|Reactome:R-HSA-901039|Reactome:R-HSA-9036012|MetaCyc:3.2.1.113-RXN|KEGG_REACTION:R06722|Reactome:R-HSA-9036011									molecular_function											owl:Class	
GO:0021769	biolink:NamedThing	orbitofrontal cortex development	The progression of the orbitofrontal cortex over time from its initial formation until its mature state. The orbitofrontal cortex is a cerebral cortex region located in the frontal lobe.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0070082	biolink:NamedThing	clathrin-sculpted monoamine transport vesicle lumen	The volume enclosed by the membrane of the clathrin-sculpted monoamine transport vesicle.	tmpzr1t_l9r_go_relaxed.owl	clathrin sculpted monoamine constitutive secretory pathway transport vesicle lumen|clathrin sculpted monoamine transport vesicle lumen													cellular_component											owl:Class	
GO:0034160	biolink:NamedThing	negative regulation of toll-like receptor 8 signaling pathway	Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 8 signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of toll-like receptor 8 signalling pathway|negative regulation of TLR8 signaling pathway													biological_process											owl:Class	
GO:0072232	biolink:NamedThing	metanephric proximal convoluted tubule segment 2 development	The process whose specific outcome is the progression of the S2 portion of the metanephric proximal convoluted tubule over time, from its formation to the mature structure. The S2 portion of the metanephric proximal tubule is involved in reabsorption of water and sodium chloride.	tmpzr1t_l9r_go_relaxed.owl	metanephric S2 development							mah	2010-03-18T03:39:28Z					biological_process											owl:Class	
GO:0071215	biolink:NamedThing	cellular response to abscisic acid stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abscisic acid stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-12-03T01:04:18Z					biological_process											owl:Class	
GO:0042735	biolink:NamedThing	protein body	A membrane-bounded plant organelle found in the developing endosperm, contains storage proteins.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0071023	biolink:NamedThing	trans spliceosomal complex	A spliceosomal complex that forms during the addition of a specific spliced leader (SL) sequence to the 5'-end of a messenger RNA primary transcript, a process which occurs in a number of eukaryotic organisms, including trypanosomatid protozoans, euglenoids, nematodes, trematodes, and chordates.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-07-30T12:00:35Z					cellular_component											owl:Class	
GO:0003058	biolink:NamedThing	hormonal regulation of the force of heart contraction	The process in which the hormones modulates the force of heart muscle contraction. A hormone is one of a group of substances formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells, in the same organism, upon which they have a specific regulatory action.	tmpzr1t_l9r_go_relaxed.owl	hormonal cardiac inotropy|hormonal regulation of the force of heart muscle contraction													biological_process											owl:Class	
GO:1902247	biolink:NamedThing	geranylgeranyl diphosphate catabolic process	The chemical reactions and pathways resulting in the breakdown of geranylgeranyl diphosphate.	tmpzr1t_l9r_go_relaxed.owl	geranylgeranyl diphosphate breakdown|geranylgeranyl diphosphate catabolism|geranylgeranyl diphosphate degradation							ms	2013-06-20T09:10:09Z					biological_process											owl:Class	
GO:0050410	biolink:NamedThing	3-oxolaurate decarboxylase activity	Catalysis of the reaction: 3-oxolaurate + H(+) = 2-undecanone + CO(2).	tmpzr1t_l9r_go_relaxed.owl	beta-ketolaurate decarboxylase activity|3-oxododecanoate carboxy-lyase activity|beta-ketoacyl decarboxylase activity|3-oxododecanoate carboxy-lyase (2-undecanone-forming)				RHEA:13385|KEGG_REACTION:R03747|MetaCyc:3-OXOLAURATE-DECARBOXYLASE-RXN|EC:4.1.1.56									molecular_function											owl:Class	
GO:0021528	biolink:NamedThing	commissural neuron differentiation in spinal cord	The process in which neuroepithelial cells in the ventral neural tube acquire specialized structural and/or functional features of commissural neurons. Commissural neurons in both vertebrates and invertebrates transfer information from one side of their bodies to the other through the midline. Differentiation includes the processes involved in commitment of a cell to a specific fate.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0050004	biolink:NamedThing	isoflavone 7-O-glucosyltransferase activity	Catalysis of the reaction: UDP-glucose + isoflavone = UDP + isoflavone 7-O-beta-D-glucoside.	tmpzr1t_l9r_go_relaxed.owl	UDPglucose:isoflavone 7-O-beta-D-glucosyltransferase activity|uridine diphosphoglucose-isoflavone 7-O-glucosyltransferase activity|UDP-glucose:isoflavone 7-O-beta-D-glucosyltransferase activity|UDPglucose:isoflavone 7-O-glucosyltransferase activity|UDPglucose-flavonoid 7-O-glucosyltransferase activity				MetaCyc:ISOFLAVONE-7-O-GLUCOSYLTRANSFERASE-RXN|RHEA:56344|EC:2.4.1.170									molecular_function											owl:Class	
GO:1990043	biolink:NamedThing	5' deoxyribonuclease (pyrimidine dimer) activity	Catalysis of the endonucleolytic cleavage immediately 5' to pyrimidine dimers to products with 5'-phosphate.	tmpzr1t_l9r_go_relaxed.owl								pr	2013-02-15T12:16:51Z					molecular_function											owl:Class	
GO:2000329	biolink:NamedThing	negative regulation of T-helper 17 cell lineage commitment	Any process that stops, prevents or reduces the frequency, rate or extent of T-helper 17 cell lineage commitment.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of T-helper 17 cell fate commitment|negative regulation of Th17 cell lineage commitment|negative regulation of Th17 fate commitment							mah	2011-01-19T09:31:53Z					biological_process											owl:Class	
GO:0030213	biolink:NamedThing	hyaluronan biosynthetic process	The chemical reactions and pathways resulting in the formation of hyaluronan, the naturally occurring anionic form of hyaluronic acid, any member of a group of glycosaminoglycans, the repeat units of which consist of beta-1,4 linked D-glucuronyl-beta-(1,3)-N-acetyl-D-glucosamine.	tmpzr1t_l9r_go_relaxed.owl	hyaluronan synthesis|hyaluronan formation|hyaluronan anabolism|hyaluronan biosynthesis													biological_process											owl:Class	
GO:0047916	biolink:NamedThing	GDP-6-deoxy-D-talose 4-dehydrogenase activity	Catalysis of the reaction: GDP-6-deoxy-D-talose + NAD(P)+ = GDP-4-dehydro-6-deoxy-D-talose + NAD(P)H + H+.	tmpzr1t_l9r_go_relaxed.owl	GDP-6-deoxy-D-talose:NAD(P)+ 4-oxidoreductase activity|guanosine diphospho-6-deoxy-D-talose dehydrogenase activity				EC:1.1.1.135|MetaCyc:GDP-6-DEOXY-D-TALOSE-4-DEHYDROGENASE-RXN									molecular_function											owl:Class	
GO:0102392	biolink:NamedThing	decanoate-[HmqF protein] ligase activity	Catalysis of the reaction: decanoate + ATP(4-) + an HmqF protein <=> AMP(2-) + diphosphoric acid + a decanoyl-HmqF protein.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-13623									molecular_function											owl:Class	
GO:1900616	biolink:NamedThing	emericellamide A catabolic process	The chemical reactions and pathways resulting in the breakdown of emericellamide A.	tmpzr1t_l9r_go_relaxed.owl	emericellamide A degradation|emericellamide A breakdown|emericellamide A catabolism							di	2012-05-15T08:00:19Z					biological_process											owl:Class	
GO:0000436	biolink:NamedThing	carbon catabolite activation of transcription from RNA polymerase II promoter	Any process involving carbon catabolites that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of transcription from RNA polymerase II promoter by carbon catabolites													biological_process											owl:Class	
GO:0030862	biolink:NamedThing	positive regulation of polarized epithelial cell differentiation	Any process that activates or increases the rate or extent of polarized epithelial cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	upregulation of polarized epithelial cell differentiation|up regulation of polarized epithelial cell differentiation|activation of polarized epithelial cell differentiation|up-regulation of polarized epithelial cell differentiation|stimulation of polarized epithelial cell differentiation													biological_process											owl:Class	
GO:0150153	biolink:NamedThing	positive regulation of interleukin-17A production	Any process that activates or increases the frequency, rate or extent of interleukin-17A production.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of interleukin-17A biosynthetic process							bc	2019-12-11T07:45:44Z					biological_process											owl:Class	
GO:0075131	biolink:NamedThing	induction by symbiont of host protein kinase-mediated signal transduction	Any process in which the symbiont activates, maintains or increases the frequency, rate or extent of protein kinase-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	positive regulation by symbiont of host protein kinase-mediated signal transduction					Note that this term is used to annotate gene products of the symbiont. To annotate host gene products, consider the biological process term "positive regulation by host of symbiont protein kinase-mediated signal transduction ; GO:0075100".								biological_process											owl:Class	
GO:0071272	biolink:NamedThing	morphine metabolic process	The chemical reactions and pathways involving morphine, 17-methyl-7,8-didehydro-4,5alpha-epoxymorphinan-3,6alpha-diol. Morphine is a highly potent opiate analgesic psychoactive drug obtained form the opium poppy, Papaver somniferum.	tmpzr1t_l9r_go_relaxed.owl	morphine metabolism				Wikipedia:Morphine			mah	2009-12-10T11:11:51Z					biological_process											owl:Class	
GO:2000447	biolink:NamedThing	negative regulation of macrophage migration inhibitory factor signaling pathway	Any process that stops, prevents or reduces the frequency, rate or extent of macrophage migration inhibitory factor signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of macrophage migration inhibitory factor signalling pathway|negative regulation of MIF signaling pathway							bf	2011-03-04T10:38:15Z					biological_process											owl:Class	
GO:0031456	biolink:NamedThing	glycine betaine biosynthetic process	The chemical reactions and pathways resulting in the formation of glycine betaine, N-trimethylglycine.	tmpzr1t_l9r_go_relaxed.owl	N-trimethylglycine biosynthesis|N-trimethylglycine biosynthetic process|glycine betaine synthesis|glycine betaine anabolism|glycine betaine formation|glycine betaine biosynthesis													biological_process											owl:Class	
GO:0080162	biolink:NamedThing	intracellular auxin transport	The directed movement of auxins within a cell. Auxins are a group of plant hormones that regulates aspects of plant growth.	tmpzr1t_l9r_go_relaxed.owl								dhl	2010-09-23T03:46:29Z					biological_process											owl:Class	
GO:0016154	biolink:NamedThing	pyrimidine-nucleoside phosphorylase activity	Catalysis of the reaction: pyrimidine nucleoside + phosphate = pyrimidine + alpha-D-ribose 1-phosphate.	tmpzr1t_l9r_go_relaxed.owl	Py-NPase activity|pyrimidine-nucleoside:phosphate alpha-D-ribosyltransferase activity				EC:2.4.2.2|MetaCyc:PYRIMIDINE-NUCLEOSIDE-PHOSPHORYLASE-RXN									molecular_function											owl:Class	
GO:0015113	biolink:NamedThing	nitrite transmembrane transporter activity	Enables the transfer of nitrite (NO2-) ions from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	nitrite/nitrate porter activity													molecular_function											owl:Class	
GO:0062112	biolink:NamedThing	fatty acid primary amide biosynthetic process	The chemical reactions and pathways resulting in the formation of a fatty acid primary amide.	tmpzr1t_l9r_go_relaxed.owl	fatty acid amide biosynthesis|FAPA biosynthetic process|FAPA biosynthesis							dph	2019-02-20T12:49:43Z					biological_process											owl:Class	
GO:0045504	biolink:NamedThing	dynein heavy chain binding	Binding to a heavy chain of the dynein complex.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0034910	biolink:NamedThing	6-hydroxy-3-succinoylpyridine hydrolase activity	Catalysis of the reaction: 6-hydroxy-3-succinoylpyridine + H2O = succinic semialdehyde + 2,5-dihydroxypyridine.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r1442									molecular_function											owl:Class	
GO:0050741	biolink:NamedThing	protein-FMN linkage via O3-riboflavin phosphoryl-L-serine	The formation of a protein-FMN linkage via O3-riboflavin phosphoryl-L-serine.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0350									biological_process											owl:Class	
GO:0002531	biolink:NamedThing	regulation of heart contraction involved in acute-phase response	Any process that modulates the frequency, rate or extent of heart contraction that contributes to the acute phase response. The acute phase response occurs during the early phases of an infection and is marked by changes in the production of plasma proteins such as C-reactive protein.	tmpzr1t_l9r_go_relaxed.owl	regulation of heart contraction during acute phase response|regulation of cardiac contraction during acute phase response													biological_process											owl:Class	
GO:0039658	biolink:NamedThing	TBK1-IKKE-DDX3 complex	A protein complex containing TBK1 (TANK-binding kinase 1), IKBKE (I-Kappa-B kinase epsilon/IKKE/IKK-epsilon) and the DEAD box family RNA helicase DDX3.	tmpzr1t_l9r_go_relaxed.owl	TBK1-IKBKE-DDX3 complex							bf	2013-07-03T16:59:27Z					cellular_component											owl:Class	
GO:0038008	biolink:NamedThing	TRAF-mediated signal transduction	The intracellular process in which a signal is passed on to downstream components within the cell via a tumor necrosis factor receptor-associated factor (TRAF). TRAFs are directly or indirectly recruited to the intracellular domains of cell surface receptors, and engage other signaling proteins to transfer the signal from a cell surface receptor to other intracellular signaling components.	tmpzr1t_l9r_go_relaxed.owl	TRAF signaling|TRAF-mediated intracellular signaling|TRAF-mediated signaling|tumor necrosis factor receptor-associated factor signaling|TRAF-mediated signalling|tumor necrosis factor receptor-associated factor signal transduction							bf	2011-06-22T04:01:54Z					biological_process											owl:Class	
GO:0032159	biolink:NamedThing	septin cap	A faint structure formed of septins found at the leading edge of growth in germ tubes and hyphae in fungal cells growing filamentously. This cap of septins colocalizes with a region of the plasma membrane that is rich in ergosterol.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0032628	biolink:NamedThing	interleukin-24 production	The appearance of interleukin-24 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	tmpzr1t_l9r_go_relaxed.owl	interleukin-24 secretion|ST16 production|interleukin-24 biosynthetic process|MDA7 production|IL-24 production											GO:0072622|GO:0045524		biological_process											owl:Class	
GO:0047394	biolink:NamedThing	glycerophosphoinositol inositolphosphodiesterase activity	Catalysis of the reaction: H2O + 1-(sn-glycero-3-phospho)-1D-myoinositol = 1D-myo-inositol 1-phosphate + glycerol.	tmpzr1t_l9r_go_relaxed.owl	D-myo-inositol 1:2-cyclic phosphate 2-phosphohydrolase activity|D-myo-inositol 1,2-cyclic phosphate 2-phosphohydrolase activity|1-D-myo-inositol-1,2-cyclic-phosphate 2-inositolphosphohydrolase activity|1-(sn-glycero-3-phospho)-1D-myo-inositol inositolphosphohydrolase activity|D-inositol 1,2-cyclic phosphate 2-phosphohydrolase activity|inositol-1,2-cyclic-phosphate 2-inositolphosphohydrolase activity|1,2-cyclic-inositol-phosphate phosphodiesterase activity				MetaCyc:3.1.4.43-RXN|EC:3.1.4.43|RHEA:14033									molecular_function											owl:Class	
GO:0033741	biolink:NamedThing	adenylyl-sulfate reductase (glutathione) activity	Catalysis of the reaction: AMP + glutathione disulfide + H(+) + sulfite = 5'-adenylyl sulfate + 2 glutathione.	tmpzr1t_l9r_go_relaxed.owl	5'-adenylylsulfate reductase activity|plant-type 5'-adenylylsulfate reductase activity|AMP,sulfite:glutathione-disulfide oxidoreductase (adenosine-5'-phosphosulfate-forming) activity|AMP,sulfite:oxidized-glutathione oxidoreductase (adenosine-5'-phosphosulfate-forming) activity				RHEA:14141|EC:1.8.4.9|KEGG_REACTION:R05717|MetaCyc:1.8.4.9-RXN									molecular_function											owl:Class	
GO:0042732	biolink:NamedThing	D-xylose metabolic process	The chemical reactions and pathways involving D-xylose, a naturally occurring plant polysaccharide.	tmpzr1t_l9r_go_relaxed.owl	D-xylose metabolism													biological_process											owl:Class	
GO:0031455	biolink:NamedThing	glycine betaine metabolic process	The chemical reactions and pathways involving glycine betaine, N-trimethylglycine.	tmpzr1t_l9r_go_relaxed.owl	glycine betaine metabolism|N-trimethylglycine metabolic process|N-trimethylglycine metabolism													biological_process											owl:Class	
GO:1900565	biolink:NamedThing	chanoclavine-I catabolic process	The chemical reactions and pathways resulting in the breakdown of chanoclavine-I.	tmpzr1t_l9r_go_relaxed.owl	chanoclavine-I catabolism|chanoclavine-I degradation|chanoclavine-I breakdown							di	2012-05-15T06:30:48Z					biological_process											owl:Class	
GO:0102042	biolink:NamedThing	dehydroquinate synthase activity	Catalysis of the reaction: 2-amino-2,3,7-trideoxy-D-lyxo-hept-6-ulosonic acid + H2O + NAD = 3-dehydroquinate + ammonium + NADH + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-10032|RHEA:25956|EC:1.4.1.24									molecular_function											owl:Class	
GO:0052873	biolink:NamedThing	FMN reductase (NADPH) activity	Catalysis of the reaction: FMNH2 + NADP+ = FMN + NADPH + 2 H+.	tmpzr1t_l9r_go_relaxed.owl	NADPH2 dehydrogenase (FMN)|FMNH2:NADP+ oxidoreductase activity|NADPH2:FMN oxidoreductase activity|flavin mononucleotide reductase activity|NADPH(2) dehydrogenase (FMN) activity|SsuE|flavine mononucleotide reductase activity|NADPH-FMN reductase activity|NADPH:flavin oxidoreductase activity|NADPH:FMN oxidoreductase activity|NADPH-dependent FMN reductase activity|NADPH(2):FMN oxidoreductase activity|NADPH dehydrogenase (FMN) activity				RHEA:21624|Reactome:R-HSA-1222399|EC:1.5.1.38|EC:1.5.1.39|KEGG_REACTION:R05706									molecular_function											owl:Class	
GO:0061421	biolink:NamedThing	positive regulation of transcription by oleic acid	Any process involving oleic acid that activates or increases the rate of transcription.	tmpzr1t_l9r_go_relaxed.owl								dph	2012-01-25T10:11:39Z					biological_process											owl:Class	
GO:0005969	biolink:NamedThing	serine-pyruvate aminotransferase complex	An enzyme complex that catalyzes the formation of hydroxypyruvate and alanine from serine and pyruvate.	tmpzr1t_l9r_go_relaxed.owl	serine-pyruvate aminotransferase, type 1 complex|serine-pyruvate aminotransferase, type 2B complex											GO:0005970		cellular_component											owl:Class	
GO:0044595	biolink:NamedThing	decaprenyldihydroxybenzoate methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + 3-decaprenyl-4,5-dihydroxybenzoate = S-adenosyl-L-homocysteine + 3-decaprenyl-4-hydroxy-5-methoxybenzoate.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-9282|RHEA:44492|Reactome:R-HSA-2162193			jl	2012-04-26T04:52:05Z					molecular_function											owl:Class	
GO:0010420	biolink:NamedThing	3,4-dihydroxy-5-polyprenylbenzoic acid O-methyltransferase activity	Catalysis of the reaction: 3,4-dihydroxy-5-polyprenylbenzoic acid + S-adenosyl-L-methionine = 3-methoxy-4-hydroxy-5-polyprenylbenzoic acid + S-adenosyl-L-homocysteine + H+.	tmpzr1t_l9r_go_relaxed.owl	polyprenyldihydroxybenzoate methyltransferase activity				MetaCyc:RXN-9281|EC:2.1.1.114|RHEA:44452			sl	2015-10-28T22:12:58Z			GO:1990886		molecular_function											owl:Class	
GO:0140140	biolink:NamedThing	mitochondrial guanine nucleotide transmembrane transport	The process in which a guanine nucleotide is transported across a mitochondrial membrane, into or out of the mitochondrion.	tmpzr1t_l9r_go_relaxed.owl								pg	2017-11-24T13:26:17Z					biological_process											owl:Class	
GO:0005584	biolink:NamedThing	collagen type I trimer	A collagen trimer containing alpha(I) chains. The most common form of type I collagen is a heterotrimer containing two alpha1(I) chains and one alpha2(I) chain; homotrimers containing three alpha1(I) chains are also found. Type I collagen triple helices associate to form banded fibrils.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Collagen_type_I									cellular_component											owl:Class	
GO:1900952	biolink:NamedThing	positive regulation of 18-methylnonadec-1-ene biosynthetic process	Any process that activates or increases the frequency, rate or extent of 18-methylnonadec-1-ene biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of 18-methylnonadec-1-ene formation|up regulation of 18-methylnonadec-1-ene biosynthetic process|up-regulation of 18-methylnonadec-1-ene synthesis|activation of 18-methylnonadec-1-ene biosynthetic process|up-regulation of 18-methylnonadec-1-ene biosynthetic process|positive regulation of 18-methylnonadec-1-ene biosynthesis|activation of 18-methylnonadec-1-ene synthesis|upregulation of 18-methylnonadec-1-ene anabolism|upregulation of 18-methylnonadec-1-ene biosynthesis|positive regulation of 18-methylnonadec-1-ene anabolism|activation of 18-methylnonadec-1-ene anabolism|activation of 18-methylnonadec-1-ene formation|positive regulation of 18-methylnonadec-1-ene synthesis|up regulation of 18-methylnonadec-1-ene formation|upregulation of 18-methylnonadec-1-ene biosynthetic process|upregulation of 18-methylnonadec-1-ene formation|activation of 18-methylnonadec-1-ene biosynthesis|up-regulation of 18-methylnonadec-1-ene biosynthesis|up-regulation of 18-methylnonadec-1-ene formation|up regulation of 18-methylnonadec-1-ene biosynthesis|up regulation of 18-methylnonadec-1-ene synthesis|up-regulation of 18-methylnonadec-1-ene anabolism|upregulation of 18-methylnonadec-1-ene synthesis|up regulation of 18-methylnonadec-1-ene anabolism							tt	2012-06-14T03:24:02Z					biological_process											owl:Class	
GO:1900955	biolink:NamedThing	positive regulation of 18-methylnonadec-1-ene metabolic process	Any process that activates or increases the frequency, rate or extent of 18-methylnonadec-1-ene metabolic process.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of 18-methylnonadec-1-ene metabolic process|upregulation of 18-methylnonadec-1-ene metabolic process|activation of 18-methylnonadec-1-ene metabolism|up-regulation of 18-methylnonadec-1-ene metabolism|positive regulation of 18-methylnonadec-1-ene metabolism|activation of 18-methylnonadec-1-ene metabolic process|upregulation of 18-methylnonadec-1-ene metabolism|up regulation of 18-methylnonadec-1-ene metabolic process|up regulation of 18-methylnonadec-1-ene metabolism							tt	2012-06-14T03:25:44Z					biological_process											owl:Class	
GO:0008663	biolink:NamedThing	2',3'-cyclic-nucleotide 2'-phosphodiesterase activity	Catalysis of the reaction: nucleoside 2',3'-cyclic phosphate + H2O = nucleoside 3'-phosphate.	tmpzr1t_l9r_go_relaxed.owl	2':3'-cyclic nucleotide phosphodiesterase:3'-nucleotidase activity|2',3'-cyclic AMP 2'-phosphohydrolase activity|2':3'-cyclic phosphodiesterase activity|2',3'-cyclic nucleotidase activity|ribonucleoside 2',3'-cyclic phosphate diesterase activity|cyclic 2',3'-nucleotide 2'-phosphodiesterase activity|nucleoside-2',3'-cyclic-phosphate 3'-nucleotidohydrolase activity|2',3'-cyclic nucleoside monophosphate phosphodiesterase|cyclic 2',3'-nucleotide phosphodiesterase|2',3 '-cyclic AMP phosphodiesterase activity|cyclic phosphodiesterase:3'-nucleotidase activity|2',3'-cyclic nucleotide phosphohydrolase				MetaCyc:CYCPHOSDIESTER-RXN|EC:3.1.4.16|RHEA:19621									molecular_function											owl:Class	
GO:0060474	biolink:NamedThing	positive regulation of flagellated sperm motility involved in capacitation	The process in which the controlled movement of a flagellated sperm cell is initiated as part of the process required for flagellated sperm to reach fertilization competence.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of sperm motility involved in capacitation													biological_process											owl:Class	
GO:0072046	biolink:NamedThing	establishment of planar polarity involved in nephron morphogenesis	Coordinated organization of groups of cells in the plane of an epithelium that contributes to the shaping of a nephron.	tmpzr1t_l9r_go_relaxed.owl	establishment of planar cell polarity involved in nephron morphogenesis							mah	2010-01-25T03:24:04Z					biological_process											owl:Class	
GO:0103103	biolink:NamedThing	UDP-glucose: 9-methylthiononylhydroximate S-glucosyltransferase activity	Catalysis of the reaction: UDP-alpha-D-glucose + 9-methylthiononylhydroximate <=> 8-methylthiooctyldesulfoglucosinolate + UDP + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXNQT-4328|EC:2.4.1.195									molecular_function											owl:Class	
GO:0061830	biolink:NamedThing	concave side of sperm head	The concave part of the late spermatid head or spermatozoon head that forms the ventral portion of the head, particularly in some rodent species.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0004477	biolink:NamedThing	methenyltetrahydrofolate cyclohydrolase activity	Catalysis of the reaction: 5,10-methenyltetrahydrofolate + H2O = 10-formyltetrahydrofolate.	tmpzr1t_l9r_go_relaxed.owl	5,10-methenyltetrahydrofolate 5-hydrolase (decyclizing)|formyl-methenyl-methylenetetrahydrofolate synthetase (combined)|5,10-methenyl-THF cyclohydrolase activity|citrovorum factor cyclodehydrase activity				Reactome:R-HSA-200661|MetaCyc:METHENYLTHFCYCLOHYDRO-RXN|RHEA:23700|Reactome:R-HSA-200740|EC:3.5.4.9|Reactome:R-HSA-6801328									molecular_function											owl:Class	
GO:0052821	biolink:NamedThing	DNA-7-methyladenine glycosylase activity	Catalysis of the reaction: DNA containing 7-methyladenine + H2O = DNA with abasic site + 7-methyladenine. This reaction is the hydrolysis of DNA by cleavage of the N-C1' glycosidic bond between the damaged DNA 7-methyladenine and the deoxyribose sugar to remove the 7-methyladenine, leaving an abasic site.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:3.2.2.21-RXN|EC:3.2.2.21			ai	2011-10-28T02:27:39Z					molecular_function											owl:Class	
GO:0039557	biolink:NamedThing	suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF7 activity	Any process in which a virus stops, prevents, or reduces a host viral-induced cytoplasmic pattern recognition receptor signaling pathway by reducing the activity of IRF7 (interferon regulatory factor-7). IRF7 a transcription factor in the RIG-I/MDA-5 signaling pathway. Viral infection triggers phosphorylation of cytoplasmic IRF7, which allows IRF7 to form a homodimer, migrate to the nucleus, and activate transcription of IFN-alpha and IFN-beta genes.	tmpzr1t_l9r_go_relaxed.owl	inhibition of host interferon regulatory factor-7 by virus|suppression by virus of host interferon regulatory factor 7 activity|inhibition of host IRF7 by virus|suppression by virus of host IRF7 activity	https://github.com/geneontology/go-ontology/issues/21985				This term is for annotation of viral proteins that counteract the host anti-viral innate immune response.		bf	2012-03-09T04:17:46Z					biological_process											owl:Class	
GO:0072545	biolink:NamedThing	tyrosine binding	Binding to 2-amino-3-(4-hydroxyphenyl)propanoic acid.	tmpzr1t_l9r_go_relaxed.owl	Tyr binding							mah	2011-01-19T05:43:55Z					molecular_function											owl:Class	
GO:0070093	biolink:NamedThing	negative regulation of glucagon secretion	Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of glucagon.	tmpzr1t_l9r_go_relaxed.owl	down regulation of glucagon secretion|down-regulation of glucagon secretion|inhibition of glucagon secretion|downregulation of glucagon secretion													biological_process											owl:Class	
GO:1904038	biolink:NamedThing	regulation of iron export across plasma membrane	Any process that modulates the frequency, rate or extent of export of iron ions from inside of a cell, across the plasma membrane and into the extracellular region.	tmpzr1t_l9r_go_relaxed.owl	regulation of ferrous iron export|regulation of iron(2+) export							kom	2015-03-16T15:36:37Z					biological_process											owl:Class	
GO:0003051	biolink:NamedThing	angiotensin-mediated drinking behavior	The drinking behavior that is mediated by the action of angiotensin in the brain. Angiotensin stimulates the brain centers that control thirst.	tmpzr1t_l9r_go_relaxed.owl	angiotensin mediated drinking behavior													biological_process											owl:Class	
GO:1901536	biolink:NamedThing	negative regulation of DNA demethylation	Any process that stops, prevents or reduces the frequency, rate or extent of DNA demethylation.	tmpzr1t_l9r_go_relaxed.owl	downregulation of DNA demethylation|down-regulation of DNA demethylation|inhibition of DNA demethylation|down regulation of DNA demethylation							jl	2012-10-24T13:52:54Z					biological_process											owl:Class	
GO:0051652	biolink:NamedThing	maintenance of chromosome location	Any process in which a chromosome is maintained in a specific location within a cell and prevented from moving elsewhere.	tmpzr1t_l9r_go_relaxed.owl	maintenance of chromosome localization													biological_process											owl:Class	
GO:0004023	biolink:NamedThing	alcohol dehydrogenase activity, metal ion-independent	Catalysis of the reaction: an alcohol + NAD+ = an aldehyde or ketone + NADH + H+; can proceed in the absence of a metal ion.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0034522	biolink:NamedThing	cis-1,2-dihydroxy-1,2-dihydro-8-carboxynaphthalene dehydrogenase activity	Catalysis of the reaction: cis-1,2-dihydroxy-1,2-dihydro-8-carboxynaphthalene = 1,2-dihydroxy-8-carboxynaphthalene + 2 H+ + 2 e-.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0774									molecular_function											owl:Class	
GO:0030131	biolink:NamedThing	clathrin adaptor complex	A membrane coat adaptor complex that links clathrin to a membrane.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0120234	biolink:NamedThing	stereocilium coat	A glycocalyx on the the endolymphatic surface of a cochlear hair cell that coats the external surface of each stereocilium and maintains a small distance between adjacent stereocilia in the bundle.	tmpzr1t_l9r_go_relaxed.owl	auditory hair cell glycocalyx|stereocilium glycocalyx	https://github.com/geneontology/go-ontology/issues/19782						krc	2020-07-15T00:56:35Z					cellular_component											owl:Class	
GO:0034027	biolink:NamedThing	(carboxyethyl)arginine beta-lactam-synthase activity	Catalysis of the reaction: N(2)-(2-carboxyethyl)-L-arginine + ATP = AMP + deoxyamidinoproclavaminate + diphosphate + 2 H(+).	tmpzr1t_l9r_go_relaxed.owl	L-2-N-(2-carboxyethyl)arginine cyclo-ligase (AMP-forming) activity|L-N2-(2-carboxyethyl)arginine cyclo-ligase (AMP-forming) activity|beta-lactam synthetase activity				KEGG_REACTION:R05467|MetaCyc:6.3.3.4-RXN|EC:6.3.3.4|RHEA:23620									molecular_function											owl:Class	
GO:2001241	biolink:NamedThing	positive regulation of extrinsic apoptotic signaling pathway in absence of ligand	Any process that activates or increases the frequency, rate or extent of extrinsic apoptotic signaling pathway in absence of ligand.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of extrinsic apoptosis in absence of ligand|positive regulation of dependence receptor signaling pathway|positive regulation of extrinsic apoptotic signalling pathway in absence of ligand							pr	2011-11-24T01:33:31Z					biological_process											owl:Class	
GO:0047988	biolink:NamedThing	hydroxyacid-oxoacid transhydrogenase activity	Catalysis of the reaction: (S)-3-hydroxybutanoate + 2-oxoglutarate = acetoacetate + (R)-2-hydroxyglutarate.	tmpzr1t_l9r_go_relaxed.owl	(S)-3-hydroxybutanoate:2-oxoglutarate oxidoreductase activity|transhydrogenase, hydroxy acid-oxo acid				Reactome:R-HSA-880002|EC:1.1.99.24|MetaCyc:HYDROXYACID-OXOACID-TRANSHYDROGENASE-RXN|Reactome:R-HSA-880033									molecular_function											owl:Class	
GO:0051174	biolink:NamedThing	regulation of phosphorus metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus.	tmpzr1t_l9r_go_relaxed.owl	regulation of phosphorus metabolism													biological_process											owl:Class	
GO:0050230	biolink:NamedThing	purine imidazole-ring cyclase activity	Catalysis of the reaction: DNA 4,6-diamino-5-formamidopyrimidine = DNA adenine + H2O.	tmpzr1t_l9r_go_relaxed.owl	DNA-4,6-diamino-5-formamidopyrimidine C8-N9-lyase (cyclizing; DNA-adenine-forming)|DNA-4,6-diamino-5-formamidopyrimidine 8-C,9-N-lyase (cyclizing; DNA-adenine-forming)|DNA-4,6-diamino-5-formamidopyrimidine 8-C,9-N-lyase (cyclizing)				MetaCyc:PURINE-IMIDAZOLE-RING-CYCLASE-RXN|EC:4.3.2.4									molecular_function											owl:Class	
GO:0071039	biolink:NamedThing	nuclear polyadenylation-dependent CUT catabolic process	The chemical reactions and pathways occurring in the nucleus and resulting in the breakdown of a cryptic unstable transcript (CUT), initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target CUT.	tmpzr1t_l9r_go_relaxed.owl	nuclear poly(A)-dependent CUT catabolic process							krc	2009-07-29T01:10:34Z					biological_process											owl:Class	
GO:0071034	biolink:NamedThing	CUT catabolic process	The chemical reactions and pathways resulting in the breakdown of cryptic unstable transcripts (CUTs).	tmpzr1t_l9r_go_relaxed.owl	cryptic unstable transcript catabolic process							krc	2009-07-29T12:38:04Z					biological_process											owl:Class	
GO:0061508	biolink:NamedThing	CDP phosphorylation	The process of introducing a phosphate group into CDP to produce a CTP.	tmpzr1t_l9r_go_relaxed.owl								dph	2013-02-21T13:38:11Z					biological_process											owl:Class	
GO:1905045	biolink:NamedThing	negative regulation of Schwann cell proliferation involved in axon regeneration	Any process that stops, prevents or reduces the frequency, rate or extent of Schwann cell proliferation involved in axon regeneration.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of Schwann cell proliferation involved in axon regeneration|downregulation of Schwann cell proliferation involved in axon regeneration|down regulation of Schwann cell proliferation involved in axon regeneration|inhibition of Schwann cell proliferation involved in axon regeneration							rph	2016-03-11T14:47:45Z					biological_process											owl:Class	
GO:0044293	biolink:NamedThing	dendriole	Small dendrites that makes up a brush structure found as the terminal specialization of a dendrite of a unipolar brush cell (UBC).	tmpzr1t_l9r_go_relaxed.owl					NIF_Subcellular:sao28175134|NIF_Subcellular:sao295057932			jl	2010-02-04T03:32:02Z					cellular_component											owl:Class	
GO:1904411	biolink:NamedThing	positive regulation of secretory granule organization	Any process that activates or increases the frequency, rate or extent of secretory granule organization.	tmpzr1t_l9r_go_relaxed.owl	upregulation of secretory granule organization|up-regulation of secretory granule organization|up-regulation of secretory granule organization and biogenesis|upregulation of secretory granule organisation|activation of secretory granule organization and biogenesis|up regulation of secretory granule organisation|upregulation of secretory granule organization and biogenesis|activation of secretory granule organization|up regulation of secretory granule organization and biogenesis|activation of secretory granule organisation|up regulation of secretory granule organization|up-regulation of secretory granule organisation|positive regulation of secretory granule organization and biogenesis|positive regulation of secretory granule organisation							sl	2015-06-25T19:40:55Z					biological_process											owl:Class	
GO:0006507	biolink:NamedThing	GPI anchor release	The GPI anchor metabolic process that results in enzymatic cleavage of the anchor, releasing an anchored protein from the membrane.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0032717	biolink:NamedThing	negative regulation of interleukin-8 production	Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-8 production.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of interleukin-8 secretion|negative regulation of IL-8 production|down regulation of interleukin-8 production|down-regulation of interleukin-8 production|inhibition of interleukin-8 production|negative regulation of interleukin-8 biosynthetic process|downregulation of interleukin-8 production											GO:0045415|GO:2000483		biological_process											owl:Class	
GO:0001666	biolink:NamedThing	response to hypoxia	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level.	tmpzr1t_l9r_go_relaxed.owl	response to lowered oxygen tension|response to sustained hypoxia|response to hypoxic stress|response to intermittent hypoxia					Note that this term should not be confused with 'response to anoxia ; GO:0034059'. Note that in laboratory studies, hypoxia is typically studied at O2 concentrations ranging from 0.1 - 5%.								biological_process											owl:Class	
GO:0097329	biolink:NamedThing	response to antimetabolite	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antimetabolite stimulus. An antimetabolite is a substance which is structurally similar to a metabolite but which competes with it or replaces it, and so prevents or reduces its normal utilization.	tmpzr1t_l9r_go_relaxed.owl								pr	2012-06-12T10:52:01Z					biological_process											owl:Class	
GO:0060166	biolink:NamedThing	olfactory pit development	The biological process whose specific outcome is the progression of the olfactory pit from an initial condition to its mature state. This process begins with the formation of the olfactory pit, which is an indentation of the olfactory placode, and ends when the pits hollows out to form the nasopharynx.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1901511	biolink:NamedThing	(-)-microperfuranone catabolic process	The chemical reactions and pathways resulting in the breakdown of (-)-microperfuranone.	tmpzr1t_l9r_go_relaxed.owl	(-)-microperfuranone degradation|(-)-microperfuranone catabolism|(-)-microperfuranone breakdown							di	2012-10-18T06:54:14Z					biological_process											owl:Class	
GO:1901510	biolink:NamedThing	(-)-microperfuranone metabolic process	The chemical reactions and pathways involving (-)-microperfuranone.	tmpzr1t_l9r_go_relaxed.owl	(-)-microperfuranone metabolism							di	2012-10-18T06:54:10Z					biological_process											owl:Class	
GO:0060959	biolink:NamedThing	cardiac neuron development	The process whose specific outcome is the progression of a cardiac neuron over time, from its formation to the mature state.	tmpzr1t_l9r_go_relaxed.owl	heart neuron development							dph	2009-09-30T10:14:56Z					biological_process											owl:Class	
GO:0060093	biolink:NamedThing	negative regulation of synaptic transmission, glycinergic	Any process that stops or decreases the frequency, rate or extent of glycinergic synaptic transmission. Glycinergic synaptic transmission is the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glycine.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of glycinergic synaptic transmission													biological_process											owl:Class	
GO:1902707	biolink:NamedThing	hexose catabolic process to ethanol	The chemical reactions and pathways resulting in the breakdown of hexose to ethanol.	tmpzr1t_l9r_go_relaxed.owl	hexose breakdown to ethanol|hexose degradation to ethanol|hexose catabolism to ethanol|solventogenesis							tb	2014-02-19T21:33:08Z			GO:1990282		biological_process											owl:Class	
GO:0047695	biolink:NamedThing	benzoin aldolase activity	Catalysis of the reaction: benzoin = 2 benzaldehyde.	tmpzr1t_l9r_go_relaxed.owl	2-hydroxy-1,2-diphenylethanone benzaldehyde-lyase 2-hydroxy-1,2-diphenylethanone benzaldehyde-lyase activity|diphenylethanone benzaldehyde-lyase activity|2-hydroxy-1,2-diphenylethanone benzaldehyde-lyase 2-hydroxy-1,2-diphenylethanone benzaldehyde-lyase (benzaldehyde-forming)|2-hydroxy-1,2-diphenylethanone benzaldehyde-lyase 2-hydroxy-1,2- activity|benzaldehyde lyase activity				MetaCyc:BENZOIN-ALDOLASE-RXN|EC:4.1.2.38|RHEA:21460|KEGG_REACTION:R00027									molecular_function											owl:Class	
GO:1990927	biolink:NamedThing	calcium ion regulated lysosome exocytosis	The process of secretion by a cell that results in the release of intracellular molecules contained within a lysosome by fusion of the vesicle with the plasma membrane of a cell, induced by a rise in cytosolic calcium-ion levels.	tmpzr1t_l9r_go_relaxed.owl								sp	2016-02-16T14:19:44Z					biological_process											owl:Class	
GO:0010451	biolink:NamedThing	floral meristem growth	The increase in size or mass of a floral meristem, a population of undifferentiated cells in a plant that gives rise to a flower.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0014899	biolink:NamedThing	cardiac muscle atrophy	A process, occurring in the heart, in which a decrease in cell mass and then in heart size occurs due to shrinking of the individual cells. The shrinkage is caused by protein degradation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0014891	biolink:NamedThing	striated muscle atrophy	A process, occurring in striated muscle, that is characterized by a decrease in protein content, fiber diameter, force production and fatigue resistance in response to different conditions such as starvation, aging and disuse.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0036080	biolink:NamedThing	purine nucleotide-sugar transmembrane transporter activity	Enables the transfer of a purine nucleotide-sugar from one side of a membrane to the other. Purine nucleotide-sugars are purine nucleotides in glycosidic linkage with a monosaccharide or monosaccharide derivative.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-12-19T03:29:06Z					molecular_function											owl:Class	
GO:0005338	biolink:NamedThing	nucleotide-sugar transmembrane transporter activity	Enables the transfer of a nucleotide-sugar from one side of a membrane to the other. A nucleotide-sugar is any nucleotide in which the distal phosphoric residue of a nucleoside 5'-diphosphate is in glycosidic linkage with a monosaccharide or monosaccharide derivative.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-744230|Reactome:R-HSA-744231							GO:0005339		molecular_function											owl:Class	
GO:1900089	biolink:NamedThing	negative regulation of inositol biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of inositol biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	down regulation of myo-inositol biosynthesis|down-regulation of vitamin Bh biosynthetic process|downregulation of inositol biosynthetic process|downregulation of myo-inositol biosynthesis|downregulation of inositol synthesis|inhibition of myo-inositol biosynthetic process|down-regulation of inositol biosynthetic process|downregulation of inositol anabolism|downregulation of vitamin Bh biosynthetic process|downregulation of inositol formation|inhibition of inositol biosynthetic process|down regulation of inositol synthesis|down regulation of inositol biosynthesis|inhibition of inositol biosynthesis|down regulation of inositol anabolism|inhibition of vitamin Bh biosynthetic process|down regulation of vitamin Bh biosynthetic process|downregulation of vitamin Bh biosynthesis|down-regulation of inositol anabolism|down-regulation of vitamin Bh biosynthesis|down regulation of vitamin Bh biosynthesis|downregulation of inositol biosynthesis|negative regulation of vitamin Bh biosynthetic process|inhibition of myo-inositol biosynthesis|negative regulation of inositol anabolism|inhibition of inositol anabolism|down regulation of inositol biosynthetic process|down-regulation of inositol formation|downregulation of myo-inositol biosynthetic process|negative regulation of myo-inositol biosynthetic process|negative regulation of inositol formation|inhibition of vitamin Bh biosynthesis|down regulation of inositol formation|negative regulation of vitamin Bh biosynthesis|down-regulation of myo-inositol biosynthetic process|down regulation of myo-inositol biosynthetic process|inhibition of inositol formation|inhibition of inositol synthesis|negative regulation of inositol synthesis|down-regulation of inositol biosynthesis|down-regulation of myo-inositol biosynthesis|negative regulation of myo-inositol biosynthesis|negative regulation of inositol biosynthesis|down-regulation of inositol synthesis							dhl	2012-02-08T06:27:28Z					biological_process											owl:Class	
GO:1901892	biolink:NamedThing	negative regulation of cell septum assembly	Any process that stops, prevents or reduces the frequency, rate or extent of cell septum assembly.	tmpzr1t_l9r_go_relaxed.owl	inhibition of cell septum assembly|down regulation of cell septum assembly|down-regulation of cell septum assembly|downregulation of cell septum assembly							tb	2013-02-06T20:14:45Z					biological_process											owl:Class	
GO:1990349	biolink:NamedThing	gap junction-mediated intercellular transport	The movement of substances between cells via gap junctions. A gap junction is a fine cytoplasmic channel, found in animal cells, that connects the cytoplasm of one cell to that of an adjacent cell, allowing ions and other molecules to pass freely between the two cells.	tmpzr1t_l9r_go_relaxed.owl								hjd	2014-03-25T18:05:44Z					biological_process											owl:Class	
GO:0033195	biolink:NamedThing	response to alkyl hydroperoxide	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alkyl hydroperoxide stimulus. Alkyl hydroperoxides are monosubstitution products of hydrogen peroxide, HOOH, where the substituent is an alkyl group.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0042297	biolink:NamedThing	vocal learning	A behavioral process whose outcome is a relatively long-lasting behavioral change whereby an organism modifies innate vocalizations to imitate sounds produced by others.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Vocal_learning	Examples include language learning by human infants and song learning in zebra finches.								biological_process											owl:Class	
GO:0031223	biolink:NamedThing	auditory behavior	The behavior of an organism in response to a sound.	tmpzr1t_l9r_go_relaxed.owl	auditory behaviour|behavioral response to sound|behavioural response to sound													biological_process											owl:Class	
GO:0106215	biolink:NamedThing	negative regulation of vesicle fusion with Golgi apparatus	Any process that stops, prevents or reduces the frequency, rate or extent of vesicle fustion with Golgi apparatus.	tmpzr1t_l9r_go_relaxed.owl								hjd	2019-06-27T15:17:17Z					biological_process											owl:Class	
GO:0038041	biolink:NamedThing	cross-receptor inhibition within G protein-coupled receptor heterodimer	Inhibition of one protomer of a G protein-coupled receptor (GPCR) heterodimer by the associated subunit. For example, agonist activation of one cytokine receptor can prevent activation of its associated cytokine receptor subunit.	tmpzr1t_l9r_go_relaxed.owl	cross-receptor inhibition within G-protein coupled receptor heterodimer							bf	2011-11-02T04:52:24Z					biological_process											owl:Class	
GO:1903546	biolink:NamedThing	protein localization to photoreceptor outer segment	A process in which a protein is transported to, or maintained in, a location within a photoreceptor outer segment.	tmpzr1t_l9r_go_relaxed.owl	protein localization in photoreceptor outer segment|protein localisation in photoreceptor outer segment|protein localisation to photoreceptor outer segment							krc	2014-10-17T21:14:11Z					biological_process											owl:Class	
GO:0047368	biolink:NamedThing	UDP-N-acetylgalactosamine-4-sulfate sulfotransferase activity	Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + UDP-N-acetyl-D-galactosamine 4-sulfate = adenosine 3',5'-diphosphate + H(+) + UDP-N-acetyl-D-galactosamine 4,6-disulfate.	tmpzr1t_l9r_go_relaxed.owl	uridine diphosphoacetylgalactosamine 4-sulfate sulfotransferase activity|3'-phosphoadenylyl-sulfate:UDP-N-acetyl-D-galactosamine-4-sulfate 6-sulfotransferase activity|uridine diphospho-N-acetylgalactosamine 4-sulfate sulfotransferase activity|UDP-N-acetylgalactosamine-4-sulphate sulphotransferase activity				EC:2.8.2.7|KEGG_REACTION:R04476|MetaCyc:2.8.2.7-RXN|RHEA:14337									molecular_function											owl:Class	
GO:2001096	biolink:NamedThing	cellotriose transport	The directed movement of a cellotrioseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl								jl	2011-09-21T02:06:27Z					biological_process											owl:Class	
GO:0097603	biolink:NamedThing	temperature-gated ion channel activity	Enables the transmembrane transfer of an ion by a channel that opens in response to a temperature stimulus (e.g. exposure to a temperature range different than the optimal temperature for that organism).	tmpzr1t_l9r_go_relaxed.owl	temperature-dependent ion channel activity|heat-activated ion channel activity|temperature-activated ion channel activity|temperature gated ion channel activity							pr	2014-05-12T13:10:42Z					molecular_function											owl:Class	
GO:0004097	biolink:NamedThing	catechol oxidase activity	Catalysis of the reaction: 2 L-dopa + O2 = 2 H2O + 2 L-dopaquinone. This reaction catalyzes exclusively the oxidation of catechols (i.e., o-diphenols) to the corresponding o-quinones.	tmpzr1t_l9r_go_relaxed.owl	o-diphenol oxidoreductase|pyrocatechol oxidase|L-DOPA monooxygenase activity|diphenol oxidase activity|dopamine monooxygenase activity|phenolase activity|o-diphenolase activity|polyphenol oxidase activity|L-dopa oxidase activity|catecholase|tyrosinase activity	https://github.com/geneontology/go-ontology/issues/21024			EC:1.10.3.1|RHEA:21632|MetaCyc:RXN-13061|MetaCyc:CATECHOL-OXIDASE-RXN	GO:0004097 describes oxidation of catechols (i.e., o-diphenols) to the corresponding o-quinones. For monooxygenation of monophenols, consider instead the term 'monophenol monooxygenase activity ; GO:0004503'.						GO:0036263|GO:0036264|GO:0102316		molecular_function											owl:Class	
GO:0090164	biolink:NamedThing	asymmetric Golgi ribbon formation	The asymmetric formation of a continuous ribbon of interconnected Golgi stacks of flat cisternae that contributes to the establishment of epithelial cell polarity.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-12-08T09:02:45Z					biological_process											owl:Class	
GO:0090161	biolink:NamedThing	Golgi ribbon formation	The formation of a continuous ribbon of interconnected Golgi stacks of flat cisternae.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-12-08T08:38:14Z					biological_process											owl:Class	
GO:0035320	biolink:NamedThing	imaginal disc-derived wing hair site selection	Determination of the site in the cell of an imaginal disc-derived wing at which a prehair initiates outgrowth. Restriction of prehair initiation to the distalmost part of a cell is essential to ensure that each wing epithelial cell produces one adult hair that points distally.	tmpzr1t_l9r_go_relaxed.owl	wing hair site selection|prehair localization													biological_process											owl:Class	
GO:0060355	biolink:NamedThing	positive regulation of cell adhesion molecule production	Any process that increases the rate, frequency or extent of cell adhesion molecule production. Cell adhesion molecule production is the appearance of a cell adhesion molecule as a result of its biosynthesis or a decrease in its catabolism.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0140715	biolink:NamedThing	serine-tRNA ligase complex	A heterodimeric enzyme complex that catalyzes the ligation of serine to tRNA(Ser), forming L-seryl-tRNA(Ser).	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/22145						pg	2021-09-15T12:38:41Z					cellular_component											owl:Class	
GO:0060203	biolink:NamedThing	clathrin-sculpted glutamate transport vesicle membrane	The lipid bilayer surrounding a clathrin-sculpted glutamate transport vesicle.	tmpzr1t_l9r_go_relaxed.owl	clathrin sculpted glutamate transport vesicle membrane|clathrin sculpted glutamate constitutive secretory pathway transport vesicle membrane													cellular_component											owl:Class	
GO:0047873	biolink:NamedThing	dolichyl-phosphatase activity	Catalysis of the reaction: dolichyl phosphate + H2O = dolichol + phosphate.	tmpzr1t_l9r_go_relaxed.owl	dolichyl monophosphate phosphatase activity|Dol-P-P phosphohydrolase activity|dolichol monophosphatase activity|polyprenylphosphate phosphatase activity|dolichol phosphate phosphatase activity|dolichyl pyrophosphate phosphatase activity|polyisoprenyl phosphate phosphatase activity|dolichyl-phosphate phosphohydrolase activity|dolichyl phosphate phosphatase activity|dolichol phosphatase activity|Dol-P phosphatase activity				RHEA:13797|MetaCyc:DOLICHYL-PHOSPHATASE-RXN|EC:3.1.3.51									molecular_function											owl:Class	
GO:0050206	biolink:NamedThing	oximinotransferase activity	Catalysis of the reaction: 2-(hydroxyimino)propanoate + acetone = acetone oxime + pyruvate.	tmpzr1t_l9r_go_relaxed.owl	transoximase activity|oximase activity|pyruvate-acetone oximinotransferase activity|oximinotransaminase activity|transoximinase activity				EC:2.6.3.1|MetaCyc:OXIMINOTRANSFERASE-RXN|KEGG_REACTION:R03796|RHEA:11624							GO:0016770		molecular_function											owl:Class	
GO:0046309	biolink:NamedThing	1,3-dichloro-2-propanol biosynthetic process	The chemical reactions and pathways resulting in the formation of 1,3-dichloro-2-propanol (DCP), a halohydrin suspected of being carcinogenic, mutagenic and genotoxic.	tmpzr1t_l9r_go_relaxed.owl	1,3-dichloro-2-propanol anabolism|1,3-dichloro-2-propanol synthesis|1,3-dichloro-2-propanol biosynthesis|1,3-dichloro-2-propanol formation													biological_process											owl:Class	
GO:0015928	biolink:NamedThing	fucosidase activity	Catalysis of the hydrolysis of fucosyl compounds, substances containing a group derived from a cyclic form of fucose or a fucose derivative.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1990423	biolink:NamedThing	RZZ complex	A kinetochore component required for both meiotic and mitotic spindle assembly checkpoints.	tmpzr1t_l9r_go_relaxed.owl	Rod-Zwilch-Zw10 complex					Example annotations for this term would be D. melanogaster mit(1)15 (Q9W4X9), rod and zwilch (Q9VA00).		jl	2014-07-23T11:16:42Z					cellular_component											owl:Class	
GO:0038168	biolink:NamedThing	epidermal growth factor receptor signaling pathway via I-kappaB kinase/NF-kappaB cascade	The series of molecular signals generated as a consequence of an epidermal growth factor receptor binding to one of its physiological ligands, where the signal is passed on within the cell via I-kappaB-kinase (IKK)-dependent activation of the transcription factor NF-kappaB.	tmpzr1t_l9r_go_relaxed.owl	EGFR signaling pathway via IKK/NF-kappaB cascade|EGFR signaling pathway via IKK-dependent activation of NF-kappaB							bf	2012-05-15T12:01:09Z					biological_process											owl:Class	
GO:0071727	biolink:NamedThing	cellular response to triacyl bacterial lipopeptide	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a triacylated bacterial lipopeptide stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to triacylated bacterial lipoprotein					Note that bacterial lipopeptides are derived from bacterial lipoproteins, but the two terms are sometimes used interchangeably in the literature.		mah	2010-03-17T02:17:49Z					biological_process											owl:Class	
GO:0071725	biolink:NamedThing	response to triacyl bacterial lipopeptide	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a triacylated bacterial lipopeptide stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to triacylated bacterial lipoprotein					Note that bacterial lipopeptides are derived from bacterial lipoproteins, but the two terms are sometimes used interchangeably in the literature.		mah	2010-03-17T02:16:40Z					biological_process											owl:Class	
GO:1902171	biolink:NamedThing	regulation of tocopherol cyclase activity	Any process that modulates the frequency, rate or extent of tocopherol cyclase activity.	tmpzr1t_l9r_go_relaxed.owl								tb	2013-05-25T00:41:14Z					biological_process											owl:Class	
GO:0099527	biolink:NamedThing	postsynapse to nucleus signaling pathway	A series of molecular signals that conveys information from the postsynapse to the nucleus via cytoskeletal transport of a protein from a postsynapse to the component to the nucleus where it affects biochemical processes that occur in the nucleus (e.g DNA transcription, mRNA splicing, or DNA/histone modifications).	tmpzr1t_l9r_go_relaxed.owl	postsynaptic signaling to nucleus													biological_process											owl:Class	
GO:1901287	biolink:NamedThing	iron-sulfur-molybdenum cofactor catabolic process	The chemical reactions and pathways resulting in the breakdown of iron-sulfur-molybdenum cofactor.	tmpzr1t_l9r_go_relaxed.owl	FeMo-co degradation|iron-molybdenum catabolic process|iron-molybdenum degradation|FeMo-co catabolism|FeMo-co breakdown|FeMo-co catabolic process|iron-sulfur-molybdenum cofactor catabolism|iron-sulfur-molybdenum cofactor degradation|iron-molybdenum catabolism|iron-sulfur-molybdenum cofactor breakdown|iron-molybdenum breakdown							yaf	2012-08-17T15:39:36Z					biological_process											owl:Class	
GO:1901286	biolink:NamedThing	iron-sulfur-molybdenum cofactor metabolic process	The chemical reactions and pathways involving iron-sulfur-molybdenum cofactor.	tmpzr1t_l9r_go_relaxed.owl	FeMo-co metabolic process|iron-molybdenum cofactor metabolism|iron-molybdenum cofactor metabolic process|FeMo-co metabolism|iron-sulfur-molybdenum cofactor metabolism							yaf	2012-08-17T15:39:14Z					biological_process											owl:Class	
GO:0097490	biolink:NamedThing	sympathetic neuron projection extension	Long distance growth of a single sympathetic neuron projection involved in cellular development. A neuron projection is a prolongation or process extending from a nerve cell, e.g. an axon or dendrite.	tmpzr1t_l9r_go_relaxed.owl	sympathetic neuronal cell projection extension|sympathetic neurite extension|sympathetic neuron process extension|sympathetic neuron protrusion extension							pr	2013-07-10T11:47:53Z					biological_process											owl:Class	
GO:1990138	biolink:NamedThing	neuron projection extension	Long distance growth of a single neuron projection involved in cellular development. A neuron projection is a prolongation or process extending from a nerve cell, e.g. an axon or dendrite.	tmpzr1t_l9r_go_relaxed.owl	neuron protrusion extension|neuronal cell projection extension|neurite extension|neuron process extension							pr	2013-07-08T08:40:45Z					biological_process											owl:Class	
GO:0018973	biolink:NamedThing	trinitrotoluene metabolic process	The chemical reactions and pathways involving trinitrotoluene, a methylated benzene molecule with three NO2 groups attached to it. This includes the explosive TNT, 1-methyl-2,4,6-trinitrobenzene.	tmpzr1t_l9r_go_relaxed.owl	trinitrotoluene metabolism				UM-BBD_pathwayID:tnt									biological_process											owl:Class	
GO:0010585	biolink:NamedThing	glutamine secretion	The controlled release of glutamine by a cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1900514	biolink:NamedThing	positive regulation of starch utilization system complex assembly	Any process that activates or increases the frequency, rate or extent of starch utilization system complex assembly.	tmpzr1t_l9r_go_relaxed.owl	activation of assembly of starch utilization system complex|activation of SUS complex assembly|up regulation of starch utilization system complex assembly|positive regulation of assembly of starch utilization system complex|up-regulation of SUS complex assembly|upregulation of SUS complex assembly|up-regulation of assembly of starch utilization system complex|activation of starch utilization system complex assembly|up regulation of assembly of starch utilization system complex|up-regulation of starch utilization system complex assembly|up regulation of SUS complex assembly|positive regulation of SUS complex assembly|upregulation of assembly of starch utilization system complex|upregulation of starch utilization system complex assembly							tt	2012-05-02T04:07:04Z					biological_process											owl:Class	
GO:1990784	biolink:NamedThing	response to dsDNA	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a double-stranded DNA stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to double-stranded DNA							sl	2015-06-24T17:54:13Z					biological_process											owl:Class	
GO:0033232	biolink:NamedThing	ABC-type D-methionine transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + D-methionine(out/in) = ADP + phosphate + D-methionine(in/out).	tmpzr1t_l9r_go_relaxed.owl	D-methionine-transporting ATPase activity|ATP-dependent D-methionine transporter activity|D-methionine transmembrane transporter activity|methionine transmembrane-transporting ATPase activity|D-methionine transporter activity|D-methionine-importing ATPase activity|D-methionine exporter|D-methionine importer|D-methionine-exporting ATPase activity|ATPase-coupled methionine transmembrane transporter activity|ATP-dependent methionine transmembrane transporter activity|ATPase-coupled D-methionine transporter activity				EC:7.4.2.11|RHEA:29779			jl	2012-08-07T15:59:50Z			GO:0032522|GO:0032521|GO:0048474|GO:1901243		molecular_function											owl:Class	
GO:0071699	biolink:NamedThing	olfactory placode morphogenesis	The process in which the anatomical structures of the olfactory placode are generated and organized. The olfactory placode is a thickening of the neural ectoderm in the head region of the vertebrate embryo which develops into the olfactory region of the nasal cavity.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-03-02T12:45:45Z					biological_process											owl:Class	
GO:0047367	biolink:NamedThing	quercetin-3,3'-bissulfate 7-sulfotransferase activity	Catalysis of the reaction: quercetin 3,3'-bissulfate + 3'-phosphoadenosine 5'-phosphosulfate = quercetin 3,3',7-trissulfate + adenosine 3',5'-bisphosphate.	tmpzr1t_l9r_go_relaxed.owl	flavonol 7-sulfotransferase activity|PAPS:flavonol 3,3'/3,4'-disulfate 7-sulfotransferase activity|3'-phosphoadenylyl-sulfate:quercetin-3,3'-bissulfate 7-sulfotransferase activity|7-sulfotransferase activity|quercetin-3,3'-bissulphate 7-sulphotransferase activity				RHEA:21860|EC:2.8.2.28|MetaCyc:2.8.2.28-RXN									molecular_function											owl:Class	
GO:0046256	biolink:NamedThing	2,4,6-trinitrotoluene catabolic process	The chemical reactions and pathways resulting in the breakdown of 2,4,6-trinitrotoluene, 1-methyl-2,4,6-trinitrobenzene, a highly explosive pale yellow crystalline solid.	tmpzr1t_l9r_go_relaxed.owl	2,4,6-trinitrotoluene degradation|2,4,6-trinitrotoluene breakdown|2,4,6-trinitrotoluene catabolism													biological_process											owl:Class	
GO:0018974	biolink:NamedThing	2,4,6-trinitrotoluene metabolic process	The chemical reactions and pathways involving 2,4,6-trinitrotoluene, 1-methyl-2,4,6-trinitrobenzene, a highly explosive pale yellow crystalline solid. It is prepared from toluene treated with concentrated sulfuric and nitric acids and is used in shells, bombs, and blasting explosives.	tmpzr1t_l9r_go_relaxed.owl	TNT metabolism|TNT metabolic process|2,4,6-trinitrotoluene metabolism													biological_process											owl:Class	
GO:0046443	biolink:NamedThing	FAD metabolic process	The chemical reactions and pathways involving FAD, the oxidized form of flavin adenine dinucleotide.	tmpzr1t_l9r_go_relaxed.owl	oxidized flavin adenine dinucleotide metabolic process|oxidized flavin-adenine dinucleotide metabolism|oxidized flavin-adenine dinucleotide metabolic process|FAD metabolism|oxidized flavin adenine dinucleotide metabolism													biological_process											owl:Class	
GO:0048825	biolink:NamedThing	cotyledon development	The process whose specific outcome is the progression of the cotyledon over time, from its formation to the mature structure. The cotyledon is the modified leaf (seed leaf), found as part of the embryo in plant seeds. It is involved in either storage or absorption of food reserves. Dicotyledonous seeds contain two cotyledons, while monocotyledonous seeds contain only one. The cotyledons may appear above ground and show photosynthetic activity in the seedling.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1903017	biolink:NamedThing	positive regulation of exo-alpha-sialidase activity	Any process that activates or increases the frequency, rate or extent of exo-alpha-sialidase activity.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of sialidase activity|up-regulation of exo-alpha-sialidase activity|up-regulation of neuraminidase activity|up regulation of exo-alpha-sialidase activity|positive regulation of alpha-neuraminidase activity|upregulation of acetylneuraminidase activity|up-regulation of N-acylneuraminate glycohydrolase activity|upregulation of neuraminidase activity|positive regulation of acetylneuraminidase activity|up regulation of acetylneuraminidase activity|activation of alpha-neuraminidase activity|positive regulation of neuraminidase activity|positive regulation of N-acylneuraminate glycohydrolase activity|upregulation of exo-alpha-sialidase activity|up regulation of acetylneuraminyl hydrolase activity|positive regulation of acetylneuraminyl hydrolase activity|up regulation of neuraminidase activity|activation of neuraminidase activity|up regulation of N-acylneuraminate glycohydrolase activity|activation of acetylneuraminidase activity|upregulation of alpha-neuraminidase activity|up-regulation of sialidase activity|up-regulation of acetylneuraminyl hydrolase activity|upregulation of N-acylneuraminate glycohydrolase activity|up-regulation of alpha-neuraminidase activity|activation of acetylneuraminyl hydrolase activity|upregulation of sialidase activity|up regulation of sialidase activity|up regulation of alpha-neuraminidase activity|upregulation of acetylneuraminyl hydrolase activity|activation of exo-alpha-sialidase activity|activation of sialidase activity|up-regulation of acetylneuraminidase activity|activation of N-acylneuraminate glycohydrolase activity					human serum amyloid P component (SAP) P02743 inhibits viral neuraminidase, NA (exo-alpha-sialidase activity) demonstrated in Figure 4A PMID:23544079, (IDA)		rl	2014-05-14T18:15:23Z					biological_process											owl:Class	
GO:0033619	biolink:NamedThing	membrane protein proteolysis	The proteolytic cleavage of a transmembrane protein leading to the release of its intracellular or ecto-domains.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0038119	biolink:NamedThing	CCL19-activated CCR7 signaling pathway	A series of molecular signals initiated by the binding of the C-C chemokine CCL19 to a C-C chemokine type 7 receptor (CCR7) on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.	tmpzr1t_l9r_go_relaxed.owl	CCL19-activated CCR7 signalling pathway							bf	2012-03-22T11:47:24Z					biological_process											owl:Class	
GO:0047020	biolink:NamedThing	15-hydroxyprostaglandin-D dehydrogenase (NADP+) activity	Catalysis of the reaction: NADP+ + (5Z,13E)-(15S)-9-alpha,15-dihydroxy-11-oxoprosta-5,13-dienoate = NADPH + H+ + (5Z,13E)-9-alpha-hydroxy-11,15-dioxoprosta-5,13-dienoate.	tmpzr1t_l9r_go_relaxed.owl	NADP-specific 15-hydroxyprostaglandin dehydrogenase|NADP-dependent 15-hydroxyprostaglandin dehydrogenase|prostaglandin D2 dehydrogenase activity|NADP-linked prostaglandin D2 dehydrogenase activity|15-hydroxyprostaglandin dehydrogenase (NADP)|prostaglandin-D 15-dehydrogenase (NADP)|(5Z,13E)-(15S)-9alpha,15-dihydroxy-11-oxoprosta-5,13-dienoate:NADP+ 15-oxidoreductase activity|prostaglandin-D 15-dehydrogenase (NADP(+)) activity|15-hydroxy PGD2 dehydrogenase activity|NADP-linked 15-hydroxyprostaglandin dehydrogenase|dehydrogenase, 15-hydroxyprostaglandin (nicotinamide adenine dinucleotide phosphate)|NADP-PGD2 dehydrogenase activity|prostaglandin-D 15-dehydrogenase (NADP+) activity|dehydrogenase, prostaglandin D2				EC:1.1.1.196|RHEA:20744|MetaCyc:1.1.1.196-RXN									molecular_function											owl:Class	
GO:1904383	biolink:NamedThing	response to sodium phosphate	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sodium phosphate stimulus.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-06-23T16:55:07Z					biological_process											owl:Class	
GO:1902074	biolink:NamedThing	response to salt	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a salt stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to salinity							mls	2013-04-22T15:41:57Z					biological_process											owl:Class	
GO:0102513	biolink:NamedThing	delphinidin 3-O-glucoside 5-O-glucosyltransferase (vanilloyl-glucose dependent) activity	Catalysis of the reaction: delphinidin 3-O-beta-D-glucoside + 1-O-vanilloyl-beta-D-glucose <=> delphinidin 3,7-di O-beta-D-glucoside + vanillate + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-14442									molecular_function											owl:Class	
GO:0043453	biolink:NamedThing	alkyne biosynthetic process	The chemical reactions and pathways resulting in the formation of an alkyne, any acyclic branched or unbranched hydrocarbon (compound composed only of carbon and hydrogen) having a carbon-carbon triple bond and the general formula CnH2n-2.	tmpzr1t_l9r_go_relaxed.owl	alkyne biosynthesis|alkyne anabolism|alkyne synthesis|alkyne formation													biological_process											owl:Class	
GO:0120247	biolink:NamedThing	acetylenic compound biosynthetic process	The chemical reactions and pathways resulting in the formation of an acetylenic compound, any compound which contains a carbon-carbon triple bond (aka C#C).	tmpzr1t_l9r_go_relaxed.owl	alkyne substituted compound anabolism|alkyne substituted compound synthesis|alkyne substituted compound biosynthetic process|alkyne substituted compound biosynthesis|alkyne substituted compound anabolic process	https://github.com/geneontology/go-ontology/issues/19842						krc	2020-08-18T01:02:36Z					biological_process											owl:Class	
GO:0019501	biolink:NamedThing	arsonoacetate catabolic process	The chemical reactions and pathways resulting in the breakdown of arsonoacetate, a synthetic, organic compound containing a single arsenic atom.	tmpzr1t_l9r_go_relaxed.owl	arsonoacetate degradation|arsonoacetate breakdown|arsonoacetate catabolism				MetaCyc:P482-PWY									biological_process											owl:Class	
GO:0002233	biolink:NamedThing	leukocyte chemotaxis involved in immune response	The movement of an immune cell in response to an external stimulus a part of an immune response.	tmpzr1t_l9r_go_relaxed.owl	leucocyte chemotaxis during immune response|immune cell chemotaxis during immune response													biological_process											owl:Class	
GO:2000869	biolink:NamedThing	positive regulation of estrone secretion	Any process that activates or increases the frequency, rate or extent of estrone secretion.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of 3-hydroxy-1,3,5(10)-estratrien-17-one secretion|positive regulation of folliculin secretion							bf	2011-07-26T08:50:19Z					biological_process											owl:Class	
GO:0021827	biolink:NamedThing	postnatal olfactory bulb interneuron migration	The migration of olfactory bulb interneuron precursors in the cerebral cortex that occurs after birth.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0031307	biolink:NamedThing	integral component of mitochondrial outer membrane	The component of the mitochondrial outer membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.	tmpzr1t_l9r_go_relaxed.owl	integral to mitochondrial outer membrane													cellular_component											owl:Class	
GO:0044693	biolink:NamedThing	trehalose:proton symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: trehalose(out) + H+(out) = trehalose(in) + H+(in).	tmpzr1t_l9r_go_relaxed.owl	trehalose:hydrogen symporter activity							jl	2012-08-15T15:19:27Z					molecular_function											owl:Class	
GO:0120138	biolink:NamedThing	regulation of phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity	Any process that modulates the frequency, rate or extent of phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity.	tmpzr1t_l9r_go_relaxed.owl								krc	2018-03-22T16:15:08Z					biological_process											owl:Class	
GO:0047621	biolink:NamedThing	acylpyruvate hydrolase activity	Catalysis of the reaction: a 3-acylpyruvate + H2O = a carboxylate + pyruvate.	tmpzr1t_l9r_go_relaxed.owl	3-acylpyruvate acylhydrolase activity				RHEA:19009|EC:3.7.1.5|UM-BBD_reactionID:r1401|MetaCyc:ACYLPYRUVATE-HYDROLASE-RXN									molecular_function											owl:Class	
GO:2001065	biolink:NamedThing	mannan binding	Binding to mannan.	tmpzr1t_l9r_go_relaxed.owl	mannoglycan binding							jl	2011-09-14T10:49:45Z					molecular_function											owl:Class	
GO:0120226	biolink:NamedThing	succinyl-CoA binding	Binding to succinyl-CoA, an omega-carboxyacyl-CoA having succinoyl as the S-acyl component.	tmpzr1t_l9r_go_relaxed.owl	succinyl-coenzyme A binding	https://github.com/geneontology/go-ontology/issues/19243						krc	2020-05-19T15:51:32Z					molecular_function											owl:Class	
GO:0061676	biolink:NamedThing	importin-alpha family protein binding	Binding to a member of the importin-alpha family.	tmpzr1t_l9r_go_relaxed.owl								dph	2015-01-10T18:25:22Z					molecular_function											owl:Class	
GO:1900803	biolink:NamedThing	brevianamide F metabolic process	The chemical reactions and pathways involving brevianamide F.	tmpzr1t_l9r_go_relaxed.owl	cyclo-L-tryptophanyl-L-proline metabolism|L-prolyl-L-tryptophan anhydride metabolic process|cyclo-L-Trp-L-Pro metabolism|cyclo-(Trp-Pro) metabolism|tryptophan-proline diketopiperazine metabolism|brevianamide F metabolism|L-prolyl-L-tryptophan anhydride metabolism|L-tryptophyl-L-proline cyclic anhydride metabolism|cyclo-L-Trp-L-Pro metabolic process|L-tryptophyl-L-proline cyclic anhydride metabolic process|cyclo-L-tryptophanyl-L-proline metabolic process|tryptophan-proline diketopiperazine metabolic process							di	2012-06-04T09:52:19Z					biological_process											owl:Class	
GO:0008892	biolink:NamedThing	guanine deaminase activity	Catalysis of the reaction: guanine + H2O = xanthine + NH3.	tmpzr1t_l9r_go_relaxed.owl	GAH activity|guanine aminohydrolase activity|guanine aminase activity|guanase activity				RHEA:14665|MetaCyc:GUANINE-DEAMINASE-RXN|EC:3.5.4.3|Reactome:R-HSA-74255									molecular_function											owl:Class	
GO:0014738	biolink:NamedThing	regulation of muscle hyperplasia	Any process that modulates the frequency, rate or extent of muscle hyperplasia.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0018865	biolink:NamedThing	acrylonitrile metabolic process	The chemical reactions and pathways involving acrylonitrile, a colorless, volatile liquid with a pungent odor. Acrylonitrile is used in the production of acrylic fibers, plastics, and synthetic rubbers.	tmpzr1t_l9r_go_relaxed.owl	acrylonitrile metabolism				UM-BBD_pathwayID:acr									biological_process											owl:Class	
GO:0046571	biolink:NamedThing	aspartate-2-keto-4-methylthiobutyrate transaminase activity	Catalysis of the reaction: 2-keto-4-methylthiobutyrate + aspartate = methionine + oxaloacetate.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0047341	biolink:NamedThing	fucose-1-phosphate guanylyltransferase activity	Catalysis of the reaction: beta-L-fucose 1-phosphate + GTP = diphosphate + GDP-L-fucose.	tmpzr1t_l9r_go_relaxed.owl	GDP-fucose diphosphorylase activity|GDP-fucose pyrophosphorylase activity|guanosine diphosphate L-fucose pyrophosphorylase activity|GTP:fucose-1-phosphate guanylyltransferase activity|GDP fucose pyrophosphorylase activity|GTP:L-fucose-1-phosphate guanylyltransferase activity|GTP:beta-L-fucose-1-phosphate guanylyltransferase activity|GDP-L-fucose pyrophosphorylase activity				MetaCyc:2.7.7.30-RXN|EC:2.7.7.30|KEGG_REACTION:R01951|RHEA:13549|Reactome:R-HSA-6787533									molecular_function											owl:Class	
GO:0044527	biolink:NamedThing	formation of peptidyl-cystine persulfide by sulphur transfer from H2S	The modification of a peptidyl-cystine residue in a protein by the direct addition of H2S, followed by the removal of 2 protons to form peptidyl-cysteine persulfide.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-03-15T09:46:23Z					biological_process											owl:Class	
GO:0103061	biolink:NamedThing	trans-methoxy-C60-meroacyl-AMP ligase activity	Catalysis of the reaction: ATP(4-) + H2O + a trans-methoxy-C60-meroacyl-[acp] <=> diphosphoric acid + a trans-methoxy-meroacyl-adenylate + a holo-[acyl-carrier protein].	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN1G-4141									molecular_function											owl:Class	
GO:0062143	biolink:NamedThing	L-propargylglycine biosynthetic process	The chemical reactions and pathways resulting in the formation of L-propargylglycine (Pra). L-propargylglycine is an antibiotic produced by Streptomyces bacteria.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/17763						dph	2019-09-02T16:45:12Z					biological_process											owl:Class	
GO:0071624	biolink:NamedThing	positive regulation of granulocyte chemotaxis	Any process that increases the rate, frequency or extent of granulocyte chemotaxis. Granulocyte chemotaxis is the movement of a granulocyte in response to an external stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-02-09T04:15:36Z					biological_process											owl:Class	
GO:0071400	biolink:NamedThing	cellular response to oleic acid	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oleic acid stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to oleate							mah	2009-12-11T04:40:38Z					biological_process											owl:Class	
GO:1990672	biolink:NamedThing	medial-Golgi-derived vesicle fusion with Golgi trans cisterna membrane	The joining of the lipid bilayer membrane around a medial-Golgi-derived vesicle to the lipid bilayer membrane around the Golgi trans cisterna. Vesicles are involved in anterograde transport.	tmpzr1t_l9r_go_relaxed.owl								bhm	2015-03-02T11:34:39Z					biological_process											owl:Class	
GO:1903499	biolink:NamedThing	regulation of mitotic actomyosin contractile ring assembly	Any process that modulates the frequency, rate or extent of mitotic actomyosin contractile ring assembly.	tmpzr1t_l9r_go_relaxed.owl	regulation of contractile ring assembly involved in mitotic cytokinesis|regulation of cytokinesis, actomyosin contractile ring assembly involved in mitotic cytokinesis|regulation of actomyosin contractile ring assembly involved in cytokinesis after mitosis|regulation of mitotic cytokinesis, actomyosin contractile ring assembly							pr	2014-09-30T10:13:50Z					biological_process											owl:Class	
GO:1905526	biolink:NamedThing	regulation of Golgi lumen acidification	Any process that modulates the frequency, rate or extent of Golgi lumen acidification.	tmpzr1t_l9r_go_relaxed.owl								dph	2016-10-05T13:16:25Z					biological_process											owl:Class	
GO:0070643	biolink:NamedThing	vitamin D 25-hydroxylase activity	Catalysis of the hydroxylation of C-25 of any form of vitamin D.	tmpzr1t_l9r_go_relaxed.owl	ergocalciferol 25-hydroxylase activity|cholecalciferol 25-hydroxylase activity|vitamin D2 25-hydroxylase activity|calciferol 25-hydroxylase activity							mah	2009-05-08T03:42:29Z					molecular_function											owl:Class	
GO:0061509	biolink:NamedThing	asymmetric protein localization to old mitotic spindle pole body	Any process in which a protein is transported to, or maintained to the old mitotic spindle pole body resulting in its being distributed asymmetrically.	tmpzr1t_l9r_go_relaxed.owl								dph	2013-02-21T13:49:26Z					biological_process											owl:Class	
GO:0061492	biolink:NamedThing	asymmetric protein localization to old or new spindle pole body	Any process in which a protein is transported to, or maintained to either the old or new spindle pole body resulting in its being distributed asymmetrically.	tmpzr1t_l9r_go_relaxed.owl								dph	2012-12-06T15:23:15Z					biological_process											owl:Class	
GO:0002171	biolink:NamedThing	low-affinity IgA receptor activity	Combining with low affinity with an immunoglobulin of an IgA isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	low affinity IgA receptor activity							hjd	2010-05-06T05:01:41Z					molecular_function											owl:Class	
GO:0019766	biolink:NamedThing	IgA receptor activity	Combining with an immunoglobulin of an IgA isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0048497	biolink:NamedThing	maintenance of floral organ identity	The process in which the identity of a floral organ is maintained. Identity is considered to be the aggregate of characteristics by which a structure is recognized.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0097073	biolink:NamedThing	interferon regulatory factor 5 complex	An interferon regulatory factor complex that consists of a homodimer of interferon regulatory factor 5.	tmpzr1t_l9r_go_relaxed.owl	IRF5:IRF5 complex							pr	2011-06-15T04:28:57Z					cellular_component											owl:Class	
GO:0005702	biolink:NamedThing	polytene chromosome weak point	A region of the polytene chromosome where the diameter is considerably decreased, probably resulting from local differences in chromosome organization.	tmpzr1t_l9r_go_relaxed.owl	constriction													cellular_component											owl:Class	
GO:0033383	biolink:NamedThing	geranyl diphosphate metabolic process	The chemical reactions and pathways involving geranyl diphosphate, the universal precursor of the monoterpenes.	tmpzr1t_l9r_go_relaxed.owl	geranyldiphosphate metabolic process|geranyl diphosphate metabolism													biological_process											owl:Class	
GO:0140539	biolink:NamedThing	regulation of melanotic encapsulation of foreign target	Any process that modulates the frequency, rate or extent of melanotic encapsulation of foreign target.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/16749						pg	2020-11-07T08:16:00Z					biological_process											owl:Class	
GO:1904018	biolink:NamedThing	positive regulation of vasculature development	Any process that activates or increases the frequency, rate or extent of vasculature development.	tmpzr1t_l9r_go_relaxed.owl	activation of vasculature development|up regulation of vascular system development|up regulation of vasculature development|up-regulation of vasculature development|activation of vascular system development|upregulation of vasculature development|up-regulation of vascular system development|positive regulation of vascular system development|upregulation of vascular system development							sl	2015-03-06T22:17:04Z					biological_process											owl:Class	
GO:0032913	biolink:NamedThing	negative regulation of transforming growth factor beta3 production	Any process that stops, prevents, or reduces the frequency, rate, or extent of production of transforming growth factor-beta3.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of TGF-B3 production|negative regulation of TGFB3 production|down regulation of transforming growth factor-beta3 production|negative regulation of transforming growth factor-beta3 production|down-regulation of transforming growth factor-beta3 production|inhibition of transforming growth factor-beta3 production|downregulation of transforming growth factor-beta3 production													biological_process											owl:Class	
GO:1901779	biolink:NamedThing	pentalenolactone catabolic process	The chemical reactions and pathways resulting in the breakdown of pentalenolactone.	tmpzr1t_l9r_go_relaxed.owl	pentalenolactone breakdown|pentalenolactone degradation|pentalenolactone catabolism							yaf	2013-01-16T09:49:42Z					biological_process											owl:Class	
GO:0110121	biolink:NamedThing	gamma-tubulin complex localization to cytoplasmic side of mitotic spindle pole body	Any process in which a gamma-tubulin complex is transported to, or maintained in, a specific location at the cytoplasmic side of the mitotic spindle pole body.	tmpzr1t_l9r_go_relaxed.owl								kmv	2018-07-27T15:49:05Z					biological_process											owl:Class	
GO:1990735	biolink:NamedThing	gamma-tubulin complex localization to mitotic spindle pole body	Any process in which a gamma-tubulin complex is transported to, or maintained in, a specific location at a mitotic spindle pole body.	tmpzr1t_l9r_go_relaxed.owl	establishment and maintenance of gamma-tubulin complex localization to mitotic spindle pole body|gamma-tubulin complex localisation to mitotic spindle pole body|gamma-tubulin complex localization to mitotic SPB							mah	2015-04-29T14:40:20Z					biological_process											owl:Class	
GO:1900533	biolink:NamedThing	palmitic acid metabolic process	The chemical reactions and pathways involving palmitic acid.	tmpzr1t_l9r_go_relaxed.owl								tb	2012-05-09T07:03:55Z					biological_process											owl:Class	
GO:1902438	biolink:NamedThing	response to vanadate(3-)	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vanadate(3-) stimulus.	tmpzr1t_l9r_go_relaxed.owl								di	2013-10-10T10:50:21Z					biological_process											owl:Class	
GO:0060511	biolink:NamedThing	creation of an inductive signal by a mesenchymal cell involved in lung induction	The process in which splanchnic mesenchymal cells send a signal over a short range to endodermal cells inducing them to form the primary lung bud.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0031130	biolink:NamedThing	creation of an inductive signal	The process in which one cell or group of cells sends a signal over a short range to another cell or group of cells of different ancestry and developmental potential, thereby effecting a developmental change in the latter.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0033320	biolink:NamedThing	UDP-D-xylose biosynthetic process	The chemical reactions and pathways resulting in the formation of UDP-D-xylose, uridinediphosphoxylose, a substance composed of xylose in glycosidic linkage with uridine diphosphate.	tmpzr1t_l9r_go_relaxed.owl	UDP-D-xylose anabolism|UDP-D-xylose formation|UDP-D-xylose synthesis|UDP-D-xylose biosynthesis				MetaCyc:PWY-4821									biological_process											owl:Class	
GO:0035126	biolink:NamedThing	post-embryonic genitalia morphogenesis	The process, occurring after embryonic development, by which the anatomical structures of the genitalia are generated and organized.	tmpzr1t_l9r_go_relaxed.owl	post-embryonic genital morphogenesis													biological_process											owl:Class	
GO:0061886	biolink:NamedThing	negative regulation of mini excitatory postsynaptic potential	Any process that decreases the frequency, rate or extent of mini excitatory postsynaptic potential. Mini excitatory postsynaptic potential is a process that leads to a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell, induced by the spontaneous release of a single vesicle of an excitatory neurotransmitter into the synapse.	tmpzr1t_l9r_go_relaxed.owl								dph	2017-05-30T15:50:08Z					biological_process											owl:Class	
GO:0032702	biolink:NamedThing	negative regulation of interleukin-19 production	Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-19 production.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of interleukin-19 biosynthetic process|inhibition of interleukin-19 production|downregulation of interleukin-19 production|down-regulation of interleukin-19 production|down regulation of interleukin-19 production|negative regulation of IL-19 production											GO:0045385		biological_process											owl:Class	
GO:1990490	biolink:NamedThing	archaeal proton-transporting A-type ATPase complex	A large proton-transporting two-sector ATPase protein complex that catalyzes the synthesis or hydrolysis of ATP by a rotational mechanism, coupled to the transport of protons across a membrane and is found in Archaea.	tmpzr1t_l9r_go_relaxed.owl	archaeal A-type ATPase protein complex|A-type ATPase protein complex							tt	2014-09-20T19:13:55Z					cellular_component											owl:Class	
GO:0047830	biolink:NamedThing	D-octopine dehydrogenase activity	Catalysis of the reaction: N2-(D-1-carboxyethyl)-L-arginine + NAD+ + H2O = L-arginine + pyruvate + NADH.	tmpzr1t_l9r_go_relaxed.owl	D-octopine synthase activity|2-N-(D-1-carboxyethyl)-L-arginine:NAD+ oxidoreductase (L-arginine-forming)|octopine:NAD oxidoreductase activity|octopine dehydrogenase activity|N2-(D-1-carboxyethyl)-L-arginine:NAD+ oxidoreductase (L-arginine-forming)|ODH activity				EC:1.5.1.11|MetaCyc:D-OCTOPINE-DEHYDROGENASE-RXN|RHEA:16285									molecular_function											owl:Class	
GO:0071494	biolink:NamedThing	cellular response to UV-C	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-C radiation stimulus. UV-C radiation (UV-C light) spans the wavelengths 100 to 280 nm.	tmpzr1t_l9r_go_relaxed.owl	cellular response to shortwave ultraviolet light stimulus|cellular response to UV-C light stimulus|cellular response to UVC light stimulus|cellular response to shortwave ultraviolet radiation stimulus|cellular response to UV-C radiation stimulus|cellular response to UVC radiation stimulus|cellular response to germicidal ultraviolet light stimulus|cellular response to germicidal ultraviolet radiation stimulus							mah	2009-12-18T02:22:01Z					biological_process											owl:Class	
GO:1904675	biolink:NamedThing	regulation of somatic stem cell division	Any process that modulates the frequency, rate or extent of somatic stem cell division.	tmpzr1t_l9r_go_relaxed.owl	regulation of somatic stem cell renewal							rph	2015-09-14T08:47:22Z					biological_process											owl:Class	
GO:0018969	biolink:NamedThing	thiocyanate metabolic process	The chemical reactions and pathways involving thiocyanate, the anion of thiocyanic acid, a toxic cyanide derivative commonly formed as a by-product in the production of gas for fuel, coke, and substances for chemical industries.	tmpzr1t_l9r_go_relaxed.owl	thiocyanic acid metabolism|thiocyanic acid metabolic process|thiocyanate metabolism				UM-BBD_pathwayID:thc|MetaCyc:P581-PWY									biological_process											owl:Class	
GO:0047057	biolink:NamedThing	vitamin-K-epoxide reductase (warfarin-sensitive) activity	Catalysis of the reaction: phylloquinol + a protein with a disulfide bond = phylloquinone + a protein with reduced L-cysteine residues.	tmpzr1t_l9r_go_relaxed.owl	vitamin K1 epoxide reductase activity|phylloquinone epoxide reductase activity	https://github.com/geneontology/go-ontology/issues/21412			RHEA:57744|Reactome:R-HSA-159790|Reactome:R-HSA-6806647|EC:1.17.4.4|MetaCyc:1.1.4.1-RXN	Formerly EC:1.1.4.1.								molecular_function											owl:Class	
GO:2001301	biolink:NamedThing	lipoxin biosynthetic process	The chemical reactions and pathways resulting in the formation of a lipoxin. A lipoxin is a non-classic eicosanoid and signalling molecule that has four conjugated double bonds and is derived from arachidonic acid.	tmpzr1t_l9r_go_relaxed.owl	lipoxin biosynthesis|lipoxin synthesis|lipoxin formation|lipoxin anabolism							bf	2012-03-07T11:11:13Z					biological_process											owl:Class	
GO:0106368	biolink:NamedThing	(deoxy)nucleoside phosphate kinase activity, dTTP as phosphate donor	Catalysis of the reaction: a 2'-deoxyribonucleoside 5'-phosphate + dTTP = a 2'-deoxyribonucleoside 5'-diphosphate + dTDP.	tmpzr1t_l9r_go_relaxed.owl					RHEA:62132			hjd	2021-03-11T20:09:34Z					molecular_function											owl:Class	
GO:0009104	biolink:NamedThing	lipopolysaccharide catabolic process	The chemical reactions and pathways resulting in the breakdown of lipopolysaccharides, any of a group of related, structurally complex components of the outer membrane of Gram-negative bacteria.	tmpzr1t_l9r_go_relaxed.owl	lipopolysaccharide catabolism|LPS catabolic process|lipopolysaccharide degradation|lipopolysaccharide breakdown													biological_process											owl:Class	
GO:0004476	biolink:NamedThing	mannose-6-phosphate isomerase activity	Catalysis of the reaction: D-mannose 6-phosphate = D-fructose 6-phosphate.	tmpzr1t_l9r_go_relaxed.owl	phosphohexomutase activity|phosphohexoisomerase activity|phosphomannose isomerase activity|D-mannose-6-phosphate aldose-ketose-isomerase activity|phosphomannoisomerase activity|D-mannose-6-phosphate ketol-isomerase activity|mannose phosphate isomerase activity				RHEA:12356|Reactome:R-HSA-532549|EC:5.3.1.8|Reactome:R-HSA-3781832|MetaCyc:MANNPISOM-RXN									molecular_function											owl:Class	
GO:0033379	biolink:NamedThing	maintenance of protease location in T cell secretory granule	A process in which a protease is maintained in a secretory granule in a T cell and prevented from moving elsewhere.	tmpzr1t_l9r_go_relaxed.owl	maintenance of protease localization in T-cell secretory granule|maintenance of protease localization in T lymphocyte secretory granule|maintenance of protease localization in T cell secretory granule|maintenance of protease localization in T-lymphocyte secretory granule													biological_process											owl:Class	
GO:0052906	biolink:NamedThing	tRNA (guanine(37)-N(1))-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + guanine(37) in tRNA = N(1)-methylguanine(37) in tRNA + S-adenosyl-L-homocysteine.	tmpzr1t_l9r_go_relaxed.owl	tRNA (m(1)G(37)) methyltransferase activity|tRNA-(N(1)G37) methyltransferase activity|transfer RNA (m(1)G(37)) methyltransferase activity				EC:2.1.1.228|MetaCyc:RXN-12458|RHEA:36899									molecular_function											owl:Class	
GO:0009019	biolink:NamedThing	tRNA (guanine-N1-)-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing N1-methylguanine.	tmpzr1t_l9r_go_relaxed.owl	S-adenosyl-L-methionine:tRNA (guanine-N1-)-methyltransferase activity|S-adenosyl-L-methionine:tRNA (guanine-1-N-)-methyltransferase activity|transfer ribonucleate guanine 1-methyltransferase activity|tRNA guanine 1-methyltransferase activity				Reactome:R-HSA-6786621|Reactome:R-HSA-6787591|Reactome:R-HSA-6782859									molecular_function											owl:Class	
GO:0000818	biolink:NamedThing	nuclear MIS12/MIND complex	A multiprotein kinetochore subcomplex that binds to centromeric chromatin and forms part of the inner kinetochore of a chromosome in the nucleus. It helps to recruit outer kinetochore subunits that will bind to microtubules. Nuclear localization arises in some organisms because the nuclear envelope is not broken down during mitosis. In S. cerevisiae, it consists of at least four proteins: Mtw1p, Nnf1p, Nsl1p, and Dsn1.	tmpzr1t_l9r_go_relaxed.owl	Mtw1p Including Nnf1p-Nsl1p-Dsn1p complex|MIND complex													cellular_component											owl:Class	
GO:0000444	biolink:NamedThing	MIS12/MIND type complex	A multiprotein kinetochore subcomplex that binds to centromeric chromatin and forms part of the inner kinetochore. It helps to recruit outer kinetochore subunits that will bind to microtubules. In humans, it consists of MIS12, DSN1, NSL1 and PMF1.	tmpzr1t_l9r_go_relaxed.owl	Mis12 complex													cellular_component											owl:Class	
GO:0000812	biolink:NamedThing	Swr1 complex	A multisubunit protein complex that is involved in chromatin remodeling. It is required for the incorporation of the histone variant H2AZ into chromatin. In S. cerevisiae, the complex contains Swr1p, a Swi2/Snf2-related ATPase, and 12 additional subunits.	tmpzr1t_l9r_go_relaxed.owl	SWR-C													cellular_component											owl:Class	
GO:0032302	biolink:NamedThing	MutSbeta complex	A heterodimer involved in binding to and correcting insertion/deletion mutations. In human the complex consists of two subunits, MSH2 and MSH3.	tmpzr1t_l9r_go_relaxed.owl	MSH2/MSH3 complex|MMR complex													cellular_component											owl:Class	
GO:0070373	biolink:NamedThing	negative regulation of ERK1 and ERK2 cascade	Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the ERK1 and ERK2 cascade.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of ERK1 and ERK2 signalling pathway|down regulation of ERK1 and ERK2 cascade|negative regulation of ERK1 and ERK2 signaling pathway|negative regulation of MAPK3 cascade|negative regulation of ERK1 cascade|down-regulation of ERK1 and ERK2 cascade|negative regulation of ERK cascade|negative regulation of ERK1/2 cascade|downregulation of ERK1 and ERK2 cascade|inhibition of ERK1 and ERK2 cascade|negative regulation of MAPK1 cascade|negative regulation of ERK2 cascade													biological_process											owl:Class	
GO:0035979	biolink:NamedThing	histone kinase activity (H2A-S139 specific)	Catalysis of the transfer of a phosphate group to the serine-139 residue of the C-terminal tail of histone H2A.	tmpzr1t_l9r_go_relaxed.owl	histone kinase activity (H2A.x-S139 specific)					Residue 1 of histone H2A is taken as the first residue following removal of the initiating Methionine (Met).		bf	2011-08-22T01:13:34Z					molecular_function											owl:Class	
GO:0039672	biolink:NamedThing	suppression by virus of host natural killer cell activation	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of natural killer cell activation in the host.	tmpzr1t_l9r_go_relaxed.owl	suppression by virus of host NK-cell activation							bf	2013-09-25T11:08:19Z					biological_process											owl:Class	
GO:1902665	biolink:NamedThing	response to isobutanol	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an isobutanol stimulus.	tmpzr1t_l9r_go_relaxed.owl	process resulting in tolerance to isobutanol|response to 2-methylpropan-1-ol											GO:1990337		biological_process											owl:Class	
GO:0016590	biolink:NamedThing	ACF complex	An ISWI complex that contains an ATPase subunit of the ISWI family (SNF2H in mammals, Isw2 in S. cerevisiae), an ACF1 homolog, and generally no other subunits, though Xenopus is an exception with a third non-conserved subunit. ACF plays roles in regulation of RNA polymerase II transcription and in DNA replication and repair.	tmpzr1t_l9r_go_relaxed.owl	ATP-utilizing chromatin assembly and remodeling factor complex													cellular_component											owl:Class	
GO:0036146	biolink:NamedThing	cellular response to mycotoxin	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mycotoxin stimulus. A mycotoxin is a toxic chemical substance produced by fungi.	tmpzr1t_l9r_go_relaxed.owl								bf	2012-03-12T11:08:22Z					biological_process											owl:Class	
GO:0044510	biolink:NamedThing	envenomation resulting in positive regulation of signal transduction in other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant positive regulation of signal transduction in the bitten organism.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-02-23T05:03:22Z					biological_process											owl:Class	
GO:0044509	biolink:NamedThing	envenomation resulting in modulation of signal transduction in other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant modulation of signal transduction in the bitten organism.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-02-23T04:58:10Z					biological_process											owl:Class	
GO:2000415	biolink:NamedThing	positive regulation of fibronectin-dependent thymocyte migration	Any process that activates or increases the frequency, rate or extent of fibronectin-dependent thymocyte migration.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of fibronectin-dependent thymic lymphocyte migration|positive regulation of fibronectin-dependent immature T-cell migration|positive regulation of fibronectin-dependent immature T cell migration|positive regulation of fibronectin-dependent immature T-lymphocyte migration|positive regulation of fibronectin-dependent immature T lymphocyte migration							mah	2011-02-23T01:39:00Z					biological_process											owl:Class	
GO:0039524	biolink:NamedThing	suppression by virus of host mRNA processing	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of mRNA processing in the host cell. mRNA processing is the conversion of a primary mRNA transcript into one or more mature mRNA(s) prior to translation into polypeptide.	tmpzr1t_l9r_go_relaxed.owl	inhibition of host pre-mRNA processing by virus|negative regulation by virus of host mRNA processing|inhibition by virus of host mRNA processing|inhibition of host mRNA processing by virus				VZ:903			bf	2011-06-22T04:51:55Z					biological_process											owl:Class	
GO:0046778	biolink:NamedThing	modification by virus of host mRNA processing	Any viral process that interferes with the processing of mRNA in the host cell.	tmpzr1t_l9r_go_relaxed.owl	viral perturbation of host mRNA processing													biological_process											owl:Class	
GO:0047675	biolink:NamedThing	arabinonate dehydratase activity	Catalysis of the reaction: D-arabinonate = 2-dehydro-3-deoxy-D-arabinonate + H(2)O.	tmpzr1t_l9r_go_relaxed.owl	D-arabinonate hydro-lyase activity|D-arabinonate hydro-lyase (2-dehydro-3-deoxy-D-arabinonate-forming)				EC:4.2.1.5|KEGG_REACTION:R03032|MetaCyc:ARABINONATE-DEHYDRATASE-RXN|RHEA:21836									molecular_function											owl:Class	
GO:1901288	biolink:NamedThing	iron-sulfur-molybdenum cofactor biosynthetic process	The chemical reactions and pathways resulting in the formation of iron-sulfur-molybdenum cofactor.	tmpzr1t_l9r_go_relaxed.owl	iron-molybdenum cofactor synthesis|iron-molybdenum cofactor biosynthetic process|iron-molybdenum cofactor formation|FeMo-co biosynthesis|FeMo-co anabolism|iron-molybdenum cofactor biosynthesis|iron-sulfur-molybdenum cofactor synthesis|FeMo-co synthesis|iron-sulfur-molybdenum cofactor biosynthesis|iron-sulfur-molybdenum cofactor formation|FeMo-co formation|FeMo-co biosynthetic process|iron-molybdenum cofactor anabolism|iron-sulfur-molybdenum cofactor anabolism							yaf	2012-08-17T15:39:48Z					biological_process											owl:Class	
GO:1990556	biolink:NamedThing	mitochondrial isopropylmalate transmembrane transport	The process in which 2-isopropylmalate(2-) is transported across a mitochondrial membrane, into or out of the mitochondrion.	tmpzr1t_l9r_go_relaxed.owl								vw	2014-11-19T12:47:11Z					biological_process											owl:Class	
GO:0050490	biolink:NamedThing	1,4-lactonase activity	Catalysis of the reaction: H2O + a 1,4-lactone = a 4-hydroxyacid.	tmpzr1t_l9r_go_relaxed.owl	1,4-lactone hydroxyacylhydrolase activity|gamma-lactonase activity				EC:3.1.1.25|RHEA:12745|MetaCyc:14-LACTONASE-RXN									molecular_function											owl:Class	
GO:0002046	biolink:NamedThing	opsin binding	Binding to an opsin, any of a group of hydrophobic, integral membrane glycoproteins located primarily in the disc membrane of rods or cones, involved in photoreception.	tmpzr1t_l9r_go_relaxed.owl	metarhodopsin binding											GO:0016030		molecular_function											owl:Class	
GO:0008447	biolink:NamedThing	L-ascorbate oxidase activity	Catalysis of the reaction: 4 L-ascorbate + O(2) <=> 4 monodehydroascorbate + 2 H(2)O.	tmpzr1t_l9r_go_relaxed.owl	AAO|AA oxidase activity|L-ascorbate:oxygen oxidoreductase activity|ascorbate dehydrogenase activity|ascorbic oxidase activity|ascorbase activity|ascorbic acid oxidase activity|L-ascorbate:O2 oxidoreductase activity|ascorbate oxidase activity|L-ascorbic acid oxidase activity	https://github.com/geneontology/go-ontology/issues/21022			RHEA:30243|EC:1.10.3.3|MetaCyc:L-ASCORBATE-OXIDASE-RXN									molecular_function											owl:Class	
GO:1900950	biolink:NamedThing	regulation of 18-methylnonadec-1-ene biosynthetic process	Any process that modulates the frequency, rate or extent of 18-methylnonadec-1-ene biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of 18-methylnonadec-1-ene biosynthesis|regulation of 18-methylnonadec-1-ene anabolism|regulation of 18-methylnonadec-1-ene synthesis|regulation of 18-methylnonadec-1-ene formation							tt	2012-06-14T03:23:34Z					biological_process											owl:Class	
GO:0098654	biolink:NamedThing	CENP-A recruiting complex	A protein complex that includes Mis16(Yippee family) and/or Mis18 (WD repeat) subunits that is involved in the deposition of centromere specific (CENP-A containing) nucleosomes at the centromere.	tmpzr1t_l9r_go_relaxed.owl	MIS18 complex													cellular_component											owl:Class	
GO:0019869	biolink:NamedThing	chloride channel inhibitor activity	Binds to and stops, prevents, or reduces the activity of a chloride channel.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0061855	biolink:NamedThing	negative regulation of neuroblast migration	Any process that stops, prevents, or reduces the frequency, rate or extent of neuroblast migration.	tmpzr1t_l9r_go_relaxed.owl								dph	2017-03-08T18:26:21Z					biological_process											owl:Class	
GO:0050943	biolink:NamedThing	negative regulation of iridophore differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of iridophore differentiation.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of iridophore differentiation|inhibition of iridophore differentiation|down regulation of iridophore differentiation|downregulation of iridophore differentiation													biological_process											owl:Class	
GO:0046180	biolink:NamedThing	ketogluconate biosynthetic process	The chemical reactions and pathways resulting in the formation of ketogluconate, the anion of ketogluconic acid, an aldonic acid derived from glucose containing a ketonic carbonyl group.	tmpzr1t_l9r_go_relaxed.owl	ketogluconate anabolism|ketogluconate biosynthesis|ketogluconate synthesis|ketogluconate formation													biological_process											owl:Class	
GO:0005148	biolink:NamedThing	prolactin receptor binding	Binding to a prolactin receptor.	tmpzr1t_l9r_go_relaxed.owl	prolactin|prolactin receptor ligand													molecular_function											owl:Class	
GO:1905062	biolink:NamedThing	positive regulation of cardioblast proliferation	Any process that activates or increases the frequency, rate or extent of cardioblast proliferation.	tmpzr1t_l9r_go_relaxed.owl	upregulation of cardioblast proliferation|activation of cardioblast proliferation|up regulation of cardioblast proliferation|up-regulation of cardioblast proliferation							bc	2016-03-21T11:00:23Z					biological_process											owl:Class	
GO:0015036	biolink:NamedThing	disulfide oxidoreductase activity	Catalysis of the reaction: substrate with reduced sulfide groups = substrate with oxidized disulfide bonds.	tmpzr1t_l9r_go_relaxed.owl	disulphide oxidoreductase activity				Reactome:R-HSA-1222644|Reactome:R-HSA-264997|Reactome:R-HSA-1222417|Reactome:R-HSA-1222690|Reactome:R-HSA-1222655									molecular_function											owl:Class	
GO:0071182	biolink:NamedThing	MAML3-RBP-Jkappa-ICN4 complex	A protein complex that consists of the intracellular domain of Notch4 (ICN4), the DNA-binding transcription factor RBP-Jkappa, and the transcriptional coactivator Mastermind-like-3 (MAML3); the complex is involved in transcriptional activation in response to Notch-mediated signaling.	tmpzr1t_l9r_go_relaxed.owl	MAML3-RBP-Jkappa-Notch4 complex							mah	2009-11-23T02:52:35Z					cellular_component											owl:Class	
GO:0030716	biolink:NamedThing	oocyte fate determination	The process in which a cell becomes capable of differentiating autonomously into an oocyte cell regardless of its environment; upon determination, the cell fate cannot be reversed.	tmpzr1t_l9r_go_relaxed.owl	oocyte cell fate determination													biological_process											owl:Class	
GO:0072010	biolink:NamedThing	glomerular epithelium development	The process whose specific outcome is the progression of the glomerular epithelium over time, from its formation to the mature structure. The glomerular epithelium is an epithelial tissue that covers the outer surfaces of the glomerulus. The glomerular epithelium consists of both parietal and visceral epithelium. Metanephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. A metanephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the metanephros.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-01-25T02:02:14Z					biological_process											owl:Class	
GO:0003829	biolink:NamedThing	beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity	Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + beta-D-galactosyl-(1->3)-N-acetyl-D-galactosaminyl-R = UDP + beta-D-galactosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->6)]-N-acetyl-D-galactosaminyl-R.	tmpzr1t_l9r_go_relaxed.owl	core 6-beta-GlcNAc-transferase A|beta6-N-acetylglucosaminyltransferase activity|beta(6)-N-acetylglucosaminyltransferase activity|uridine diphosphoacetylglucosamine-mucin beta-(1->6)-acetylglucosaminyltransferase activity|core 2 acetylglucosaminyltransferase activity|uridine diphosphoacetylglucosamine-mucin beta-(1,6)-acetylglucosaminyltransferase activity|UDP-N-acetyl-D-glucosamine:O-glycosyl-glycoprotein (N-acetyl-D-glucosamine to N-acetyl-D-galactosamine of beta-D-galactosyl-1,3-N-acetyl-D-galactosaminyl-R) beta-1,6-N-acetyl-D-glucosaminyltransferase activity|O-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase I activity	https://github.com/geneontology/go-ontology/issues/21793			Reactome:R-HSA-914012|Reactome:R-HSA-914018|RHEA:18705|MetaCyc:2.4.1.102-RXN|EC:2.4.1.102									molecular_function											owl:Class	
GO:0034436	biolink:NamedThing	glycoprotein transport	The directed movement of a glycoprotein, a protein that contains covalently bound glycose (i.e. monosaccharide) residues, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0072177	biolink:NamedThing	mesonephric duct development	The process whose specific outcome is the progression of a mesonephric duct over time, from its initial formation to a mature structure. A mesonephric duct is a tube drains the mesonephros.	tmpzr1t_l9r_go_relaxed.owl	Wolffian duct development							mah	2010-02-26T02:32:22Z					biological_process											owl:Class	
GO:0005262	biolink:NamedThing	calcium channel activity	Enables the facilitated diffusion of a calcium ion (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-139854|Reactome:R-HSA-8949145|Reactome:R-HSA-139855|Reactome:R-HSA-210420|Reactome:R-HSA-8949178|Reactome:R-HSA-3295579									molecular_function											owl:Class	
GO:0010032	biolink:NamedThing	meiotic chromosome condensation	Compaction of chromatin structure prior to meiosis in eukaryotic cells.	tmpzr1t_l9r_go_relaxed.owl	chromosome condensation involved in meiotic cell cycle													biological_process											owl:Class	
GO:0061818	biolink:NamedThing	tRNA folding	The process of assisting in the folding of tRNAs into the correct tertiary structure.	tmpzr1t_l9r_go_relaxed.owl								dph	2016-12-13T15:54:40Z					biological_process											owl:Class	
GO:0045615	biolink:NamedThing	positive regulation of plasmatocyte differentiation	Any process that activates or increases the frequency, rate or extent of plasmatocyte differentiation.	tmpzr1t_l9r_go_relaxed.owl	stimulation of plasmatocyte differentiation|up-regulation of plasmatocyte differentiation|activation of plasmatocyte differentiation|upregulation of plasmatocyte differentiation|up regulation of plasmatocyte differentiation													biological_process											owl:Class	
GO:0103073	biolink:NamedThing	anandamide amidohydrolase activity	Catalysis of the reaction: anandamide + H2O <=> arachidonate + ethanolaminium(1+).	tmpzr1t_l9r_go_relaxed.owl					RHEA:26136|MetaCyc:RXN6666-2|EC:3.5.1.99									molecular_function											owl:Class	
GO:0140431	biolink:NamedThing	DNA-(abasic site) binding	Binding to a DNA site that has neither a purine nor a pyrimidine base. Apurinic sites can form spontaneously or when DNA glycosylase removes a damaged base.	tmpzr1t_l9r_go_relaxed.owl	DNA AP site binding|DNA-(apurinic site/apyrimidinic site) binding|DNA-(apurinic site) binding|DNA-(apyrimidinic site) binding	https://github.com/geneontology/go-ontology/issues/18878						pg	2020-02-19T05:30:09Z					molecular_function											owl:Class	
GO:0018866	biolink:NamedThing	adamantanone metabolic process	The chemical reactions and pathways involving adamantanone, tricyclo(3.3.1.13,7)decanone, a white crystalline solid used as an intermediate for microelectronics in the production of photoresists.	tmpzr1t_l9r_go_relaxed.owl	adamantanone metabolism				UM-BBD_pathwayID:ada									biological_process											owl:Class	
GO:0033348	biolink:NamedThing	tetrose biosynthetic process	The chemical reactions and pathways resulting in the formation of a tetrose, any monosaccharide with a chain of four carbon atoms in the molecule.	tmpzr1t_l9r_go_relaxed.owl	tetrose synthesis|tetrose anabolism|tetrose biosynthesis|tetrose formation													biological_process											owl:Class	
GO:0033347	biolink:NamedThing	tetrose metabolic process	The chemical reactions and pathways involving a tetrose, any monosaccharide with a chain of four carbon atoms in the molecule.	tmpzr1t_l9r_go_relaxed.owl	tetrose metabolism													biological_process											owl:Class	
GO:0050249	biolink:NamedThing	Renilla-luciferin sulfotransferase activity	Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + Renilla luciferin = adenosine 3',5'-diphosphate + H(+) + luciferyl sulfate.	tmpzr1t_l9r_go_relaxed.owl	3'-phosphoadenylyl-sulfate:Renilla luciferin sulfotransferase activity|luciferin sulfokinase activity|luciferin sulfotransferase activity|luciferin sulfokinase (3'-phosphoadenylyl sulfate:luciferin sulfotransferase)|Renilla-luciferin sulphotransferase activity				KEGG_REACTION:R03138|MetaCyc:RENILLA-LUCIFERIN-SULFOTRANSFERASE-RXN|EC:2.8.2.10|RHEA:20481									molecular_function											owl:Class	
GO:0072053	biolink:NamedThing	renal inner medulla development	The process whose specific outcome is the progression of the renal inner medulla over time, from its formation to the mature structure. The renal inner medulla is unique to mammalian kidneys and is the innermost region of the mammalian kidney.	tmpzr1t_l9r_go_relaxed.owl	inner renal medulla development							mah	2010-01-25T03:59:37Z					biological_process											owl:Class	
GO:0008495	biolink:NamedThing	protoheme IX farnesyltransferase activity	Catalysis of the reaction: protoheme IX + (2E,6E)-farnesyl diphosphate + H2O = heme O + diphosphate.	tmpzr1t_l9r_go_relaxed.owl	heme A:farnesyltransferase activity|protohaem IX farnesyltransferase activity|heme O synthase activity|haem O synthase activity				EC:2.5.1.141|RHEA:28070|Reactome:R-HSA-2995330|MetaCyc:HEMEOSYN-RXN									molecular_function											owl:Class	
GO:0004311	biolink:NamedThing	farnesyltranstransferase activity	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate + isopentenyl diphosphate = diphosphate + geranylgeranyl diphosphate.	tmpzr1t_l9r_go_relaxed.owl	geranylgeranyl pyrophosphate synthase activity|farnesyltransferase activity|trans,trans-farnesyl-diphosphate:isopentenyl-diphosphate farnesyltranstransferase activity|geranylgeranyl-PP synthetase activity|geranylgeranyl-diphosphate synthase activity|geranylgeranyl pyrophosphate synthetase activity				EC:2.5.1.29|RHEA:17653|KEGG_REACTION:R02061|MetaCyc:FARNESYLTRANSTRANSFERASE-RXN	The catalyzed reaction forms (free) geranylgeranyl diphosphate.  There is no relationship between this activity and protein farnesyltransferase activity, GO:0004660, where the catalyzed reaction transfers a farnesyl group from farnesyl diphosphate to a target protein.								molecular_function											owl:Class	
GO:0070846	biolink:NamedThing	Hsp90 deacetylation	The modification of an Hsp90 protein by removal of acetyl groups.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-07-31T12:58:47Z					biological_process											owl:Class	
GO:0075002	biolink:NamedThing	adhesion of symbiont germination tube to host	The attachment of a germination tube of the symbiont to its host via adhesion molecules. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	adhesion of symbiont germination tube to host during symbiotic interaction					Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products from the symbiont involved in this process.								biological_process											owl:Class	
GO:0075001	biolink:NamedThing	adhesion of symbiont infection structure to host	The attachment of an infection structure of the symbiont to its host via adhesion molecules, general stickiness etc., either directly or indirectly. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	adhesion of symbiont infection structure to host during symbiotic interaction|attachment of symbiont infection structure to host					Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products of the symbiont involved in this process.								biological_process											owl:Class	
GO:0005132	biolink:NamedThing	type I interferon receptor binding	Binding to an interferon-type I receptor, a heterodimeric complex composed of an alpha subunit (IFNAR1) and a beta subunit (IFNAR2).	tmpzr1t_l9r_go_relaxed.owl	IFNAR2 binding|IFNAR binding|interferon-alpha/beta receptor ligand|IFNAR1 binding|interferon-alpha/beta receptor binding|interferon-alpha/beta													molecular_function											owl:Class	
GO:1902631	biolink:NamedThing	negative regulation of membrane hyperpolarization	Any process that stops, prevents or reduces the frequency, rate or extent of membrane hyperpolarization.	tmpzr1t_l9r_go_relaxed.owl	inhibition of membrane hyperpolarization|down regulation of membrane hyperpolarization|down-regulation of membrane hyperpolarization|downregulation of membrane hyperpolarization							krc	2014-01-17T18:28:05Z					biological_process											owl:Class	
GO:0019307	biolink:NamedThing	mannose biosynthetic process	The chemical reactions and pathways resulting in the formation of mannose, the aldohexose manno-hexose, the C-2 epimer of glucose.	tmpzr1t_l9r_go_relaxed.owl	mannose anabolism|mannose synthesis|mannose formation|mannose biosynthesis													biological_process											owl:Class	
GO:0006013	biolink:NamedThing	mannose metabolic process	The chemical reactions and pathways involving mannose, the aldohexose manno-hexose, the C-2 epimer of glucose. The D-(+)-form is widely distributed in mannans and hemicelluloses and is of major importance in the core oligosaccharide of N-linked oligosaccharides of glycoproteins.	tmpzr1t_l9r_go_relaxed.owl	mannose metabolism													biological_process											owl:Class	
GO:0035732	biolink:NamedThing	nitric oxide storage	The accumulation and maintenance in cells or tissues of nitric oxide (NO). Nitric oxide is stored in the form of dinitrosyl-iron complexes, which are stabilized, and possibly sequestered, by binding to glutathione S-transferase proteins.	tmpzr1t_l9r_go_relaxed.owl	NO storage							bf	2011-03-11T10:00:31Z					biological_process											owl:Class	
GO:0004848	biolink:NamedThing	ureidoglycolate hydrolase activity	Catalysis of the reaction: (S)-ureidoglycolate + H(2)O + 2 H(+) = CO(2) + glyoxylate + 2 NH(4)(+).	tmpzr1t_l9r_go_relaxed.owl	(S)-ureidoglycolate amidohydrolase (decarboxylating)				RHEA:19809|MetaCyc:UREIDOGLYCOLATE-HYDROLASE-RXN|KEGG_REACTION:R00469|EC:3.5.3.19	Take care to annotate to the reaction, not simply the enzyme name. The name "ureidoglycolate hydrolase" has variously been used to refer to two distinctly different enzymes. Both enzymes act on ureidoglycolate and produce glyoxylate, but the mechanism and reaction products are different. The "ureidoglycolate hydrolase" listed in the Enzyme commission (EC) is a ureidoglycolate amidohydrolase, releasing ammonia, (EC:3.5.3.19, GO:0004848). The "ureidoglycolate hydrolase" characterized in PMID:3915539 (published prior to the EC designation of EC:3.5.3.19) is a ureidoglycolate lyase, releasing urea (EC:4.3.2.3, GO:0050385). The inappropriate labelling of ureidoglycolate lyase as EC:3.5.3.19 has caused much confusion in the literature (see PMID:24107613). Take care to correctly annotate based on the reaction products, rather than name.								molecular_function											owl:Class	
GO:0002135	biolink:NamedThing	CTP binding	Binding to CTP, cytidine 5'-triphosphate.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0002606	biolink:NamedThing	positive regulation of dendritic cell antigen processing and presentation	Any process that activates or increases the frequency, rate, or extent of dendritic cell antigen processing and presentation.	tmpzr1t_l9r_go_relaxed.owl	activation of dendritic cell antigen processing and presentation|stimulation of dendritic cell antigen processing and presentation|upregulation of dendritic cell antigen processing and presentation|up regulation of dendritic cell antigen processing and presentation|up-regulation of dendritic cell antigen processing and presentation													biological_process											owl:Class	
GO:0018378	biolink:NamedThing	cytochrome c-heme linkage via heme-L-cysteine	The linkage of cytochromes and other heme proteins to heme via heme-L-cysteine.	tmpzr1t_l9r_go_relaxed.owl	cytochrome c-haem linkage via haem-L-cysteine				RESID:AA0135									biological_process											owl:Class	
GO:0019454	biolink:NamedThing	L-cysteine catabolic process via cystine, using glutathione-cystine transhydrogenase	The chemical reactions and pathways resulting in the breakdown, via the compound cystine, of L-cysteine, catalyzed by the enzyme glutathione-cystine transhydrogenase (EC:1.8.4.4).	tmpzr1t_l9r_go_relaxed.owl	L-cysteine degradation via cystine, using glutathione-cystine transhydrogenase|L-cysteine breakdown via cystine, using glutathione-cystine transhydrogenase													biological_process											owl:Class	
GO:0042044	biolink:NamedThing	fluid transport	The directed movement of substances that are in liquid form in normal living conditions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0009685	biolink:NamedThing	gibberellin metabolic process	The chemical reactions and pathways involving gibberellin. Gibberellins are a class of highly modified terpenes that function as plant growth regulators.	tmpzr1t_l9r_go_relaxed.owl	gibberellic acid metabolism|gibberellic acid metabolic process|gibberellin metabolism													biological_process											owl:Class	
GO:1900235	biolink:NamedThing	negative regulation of Kit signaling pathway	Any process that stops, prevents or reduces the frequency, rate or extent of Kit signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of stem cell factor receptor signaling pathway|downregulation of stem cell factor receptor signaling pathway|negative regulation of Kit signalling pathway|inhibition of stem cell factor signaling pathway|downregulation of stem cell factor signaling pathway|down-regulation of stem cell factor receptor signaling pathway|down regulation of stem cell factor receptor signaling pathway|inhibition of stem cell factor receptor signaling pathway|downregulation of Kit signaling pathway|down-regulation of stem cell factor signaling pathway|down regulation of Kit signaling pathway|inhibition of Kit signaling pathway|down-regulation of Kit signaling pathway|down regulation of stem cell factor signaling pathway|negative regulation of stem cell factor signaling pathway							bf	2012-03-23T02:54:23Z					biological_process											owl:Class	
GO:0002395	biolink:NamedThing	immune response in nasopharyngeal-associated lymphoid tissue	An immune response taking place in the nasopharyngeal-associated lymphoid tissue (NALT). NALT includes the tonsils and adenoids.	tmpzr1t_l9r_go_relaxed.owl	immune response in NALT													biological_process											owl:Class	
GO:0043836	biolink:NamedThing	xanthine hydrolase activity	Catalysis of the reaction: xanthine + H2O = 4-ureido-5-imidazole carboxylate.	tmpzr1t_l9r_go_relaxed.owl	xanthinase activity				MetaCyc:R127-RXN									molecular_function											owl:Class	
GO:0009440	biolink:NamedThing	cyanate catabolic process	The chemical reactions and pathways resulting in the breakdown of cyanate, NCO-, the anion of cyanic acid.	tmpzr1t_l9r_go_relaxed.owl	cyanate breakdown|cyanate catabolism|cyanate degradation													biological_process											owl:Class	
GO:0071598	biolink:NamedThing	neuronal ribonucleoprotein granule	A ribonucleoprotein complex that is found in the cytoplasm of axons and dendrites, and transports translationally silenced mRNAs to dendritic synapses, where they are released and translated in response to specific exogenous stimuli.	tmpzr1t_l9r_go_relaxed.owl	neuronal RNA granule|neuronal RNP granule							mah	2010-02-04T04:01:57Z					cellular_component											owl:Class	
GO:0098850	biolink:NamedThing	extrinsic component of synaptic vesicle membrane	The component of the synaptic vesicle membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0004552	biolink:NamedThing	octanol dehydrogenase activity	Catalysis of the reaction: 1-octanol + NAD(+) = 1-octanal + H(+) + NADH.	tmpzr1t_l9r_go_relaxed.owl	1-octanol dehydrogenase activity|octanol:NAD+ oxidoreductase activity				EC:1.1.1.73|MetaCyc:OCTANOL-DEHYDROGENASE-RXN|KEGG_REACTION:R02878|RHEA:24620									molecular_function											owl:Class	
GO:0047257	biolink:NamedThing	diglucosyl diacylglycerol synthase activity	Catalysis of the reaction: 1,2-diacyl-3-O-(alpha-D-glucopyranosyl)-sn-glycerol + UDP-D-glucose = UDP + 1,2-diacyl-3-O-(alpha-D-glucopyranosyl(1,2)-O-alpha-D-glucopyranosyl)-sn-glycerol.	tmpzr1t_l9r_go_relaxed.owl	MGlcDAG (1->2) glucosyltransferase activity|monoglucosyl diacylglycerol (1->2) glucosyltransferase activity|UDP-glucose:1,2-diacyl-3-O-(alpha-D-glucopyranosyl)-sn-glycerol (1->2) glucosyltransferase activity|diglucosyl diacylglycerol (DGlcDAG) synthase activity|DGlcDAG synthase activity				RHEA:19165|MetaCyc:2.4.1.208-RXN|EC:2.4.1.208									molecular_function											owl:Class	
GO:1990862	biolink:NamedThing	nuclear membrane complex Bqt3-Bqt4	A protein complex that resides in the inner nuclear membrane and anchors telomeres to the nuclear envelope. In fission yeast, it is composed of Bqt3 and Bqt4.	tmpzr1t_l9r_go_relaxed.owl								al	2015-09-25T12:14:28Z					cellular_component											owl:Class	
GO:0034549	biolink:NamedThing	N-cyclopropylammelide alkylamino hydrolase activity	Catalysis of the reaction: N-cyclopropylammelide + H2O = cyclopropylamine + cyanuric acid.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-8020|KEGG_REACTION:R06972|UM-BBD_reactionID:r0827									molecular_function											owl:Class	
GO:0039010	biolink:NamedThing	specification of pronephric distal tubule identity	The process in which the distal tubule of the pronephric nephron acquires its identity.	tmpzr1t_l9r_go_relaxed.owl								bf	2010-07-02T09:51:28Z					biological_process											owl:Class	
GO:0009302	biolink:NamedThing	sno(s)RNA transcription	The synthesis of snoRNA class RNA (also referred to as sRNA in Archaea) from a DNA template.	tmpzr1t_l9r_go_relaxed.owl	sRNA transcription|snoRNA transcription	https://github.com/geneontology/go-ontology/issues/20416												biological_process											owl:Class	
GO:0003870	biolink:NamedThing	5-aminolevulinate synthase activity	Catalysis of the reaction: glycine + H(+) + succinyl-CoA = 5-aminolevulinate + CO(2) + CoA.	tmpzr1t_l9r_go_relaxed.owl	delta-aminolevulinate synthetase activity|ALAS activity|delta-ALA synthetase activity|ALA synthase activity|succinyl-CoA:glycine C-succinyltransferase (decarboxylating)|5-aminolevulinate synthetase activity|aminolevulinic acid synthetase activity|delta-aminolevulinic acid synthetase activity|ALA synthetase activity|delta-aminolevulinic acid synthase activity|5-aminolevulinic acid synthetase activity|delta-aminolevulinic synthetase activity|aminolevulinate synthetase activity|5-aminolevulinic acid synthase activity|aminolevulinic synthetase activity|aminolevulinic acid synthase activity|delta-aminolevulinate synthase activity|alpha-aminolevulinic acid synthase activity|aminolevulinate synthase activity				EC:2.3.1.37|Reactome:R-HSA-189442|KEGG_REACTION:R00830|RHEA:12921|MetaCyc:5-AMINOLEVULINIC-ACID-SYNTHASE-RXN									molecular_function											owl:Class	
GO:0016749	biolink:NamedThing	N-succinyltransferase activity	Catalysis of the transfer of a succinyl group to a nitrogen atom on the acceptor molecule.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0019203	biolink:NamedThing	carbohydrate phosphatase activity	Catalysis of the reaction: carbohydrate phosphate + H2O = carbohydrate + phosphate.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-3791349|Reactome:R-HSA-3781011|Reactome:R-HSA-3781018									molecular_function											owl:Class	
GO:0008353	biolink:NamedThing	RNA polymerase II CTD heptapeptide repeat kinase activity	Catalysis of the reaction: ATP + (DNA-directed RNA polymerase II) = ADP + phospho-(DNA-directed RNA polymerase II); phosphorylation occurs on residues in the carboxy-terminal domain (CTD) repeats.	tmpzr1t_l9r_go_relaxed.owl	RNA polymerase subunit kinase activity|CTD kinase activity|ATP:DNA-directed RNA polymerase phosphotransferase activity|[RNA-polymerase]-subunit kinase activity|RNA polymerase II carboxy-terminal domain kinase activity|RNA-polymerase-subunit kinase activity|STK9				MetaCyc:RNA-POLYMERASE-SUBUNIT-KINASE-RXN|EC:2.7.11.23|Reactome:R-HSA-167191|RHEA:10216|Reactome:R-HSA-170706|Reactome:R-HSA-170704									molecular_function											owl:Class	
GO:0021944	biolink:NamedThing	neuronal-glial interaction involved in hindbrain glial-mediated radial cell migration	The changes in adhesion between a neuronal cell and a glial cell as a component of the process of hindbrain glial-mediated radial cell migration.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0015129	biolink:NamedThing	lactate transmembrane transporter activity	Enables the transfer of lactate from one side of a membrane to the other. Lactate is 2-hydroxypropanoate, CH3-CHOH-COOH; L(+)-lactate is formed by anaerobic glycolysis in animal tissues, and DL-lactate is found in sour milk, molasses and certain fruit juices.	tmpzr1t_l9r_go_relaxed.owl	monocarboxylate (lactate, pyruvate, mevalonate) uptake/efflux porter activity				Reactome:R-HSA-373867|Reactome:R-HSA-373875									molecular_function											owl:Class	
GO:0071245	biolink:NamedThing	cellular response to carbon monoxide	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbon monoxide (CO) stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-12-03T02:44:43Z					biological_process											owl:Class	
GO:0061801	biolink:NamedThing	laminin-5B complex	A laminin complex composed of alpha3B, beta3 and gamma2 polypeptide chains.	tmpzr1t_l9r_go_relaxed.owl	laminin 3B32 complex							dph	2016-10-26T15:05:15Z					cellular_component											owl:Class	
GO:0042724	biolink:NamedThing	thiamine-containing compound biosynthetic process	The chemical reactions and pathways resulting in the formation of thiamine (vitamin B1), and related compounds.	tmpzr1t_l9r_go_relaxed.owl	thiamine and derivative biosynthetic process|thiamine-containing compound biosynthesis|thiamin-containing compound biosynthetic process|vitamin B1 and derivative biosynthetic process|thiamine-containing compound formation|vitamin B1 and derivative biosynthesis|thiamine-containing compound anabolism|thiamin and derivative biosynthetic process|thiamine and derivative biosynthesis|thiamine-containing compound synthesis|thiamin and derivative biosynthesis													biological_process											owl:Class	
GO:0106402	biolink:NamedThing	Lewis x epitope biosynthetic process	The chemical reactions and pathways resulting in the formation of a Lewis x epitope, a trisaccharide (beta-D-galactosyl-(1,4)-[alpha-L-fucosyl-(1,3)]-N-acetyl-beta-D-glucosamine) expressed on several glycolipids, glycoproteins, and proteoglycans of the nervous system. The related Lewis x epitope is formed by alpha(1,3) fucosylation of the N-acetylglucosaminyl residue of a type 2 histo-blood group antigen precursor disaccharide.	tmpzr1t_l9r_go_relaxed.owl	sialyl-Lewis X biosynthetic process|sLeX biosynthetic process							hjd	2021-10-12T20:20:55Z					biological_process											owl:Class	
GO:2000430	biolink:NamedThing	positive regulation of neutrophil aggregation	Any process that activates or increases the frequency, rate or extent of neutrophil aggregation.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of neutrophilic leukocyte aggregation|positive regulation of neutrophil leucocyte aggregation|positive regulation of neutrocyte aggregation							ebc	2011-02-28T05:19:51Z					biological_process											owl:Class	
GO:0009811	biolink:NamedThing	stilbene biosynthetic process	The chemical reactions and pathways resulting in the formation of stilbenes, a class of polyketide compounds formed from cinnamic acid and three molecules of malonyl CoA.	tmpzr1t_l9r_go_relaxed.owl	stilbene biosynthesis|stilbene synthesis|stilbene formation|stilbene anabolism													biological_process											owl:Class	
GO:0008551	biolink:NamedThing	P-type cadmium transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Cd2+(in) -> ADP + phosphate + Cd2+(out).	tmpzr1t_l9r_go_relaxed.owl	cadmium-translocating P-type ATPase activity|cadmium-exporting ATPase activity|Cd(2+)-exporting ATPase activity|Cd2+-exporting ATPase activity|cadmium exporting ATPase activity|cadmium transmembrane transporter activity, phosphorylative mechanism				RHEA:12132|EC:7.2.2.21|MetaCyc:3.6.3.3-RXN							GO:0008561		molecular_function											owl:Class	
GO:0002538	biolink:NamedThing	arachidonic acid metabolite production involved in inflammatory response	The synthesis or release of products of arachidonic acid metabolism following a stimulus as part of an inflammatory response, resulting in an increase in their intracellular or extracellular levels.	tmpzr1t_l9r_go_relaxed.owl	arachidonic acid metabolite production involved in acute inflammatory response|production of arachidonic acid metabolites involved in acute inflammatory response|production of arachidonic acid metabolites involved in inflammatory response													biological_process											owl:Class	
GO:0032144	biolink:NamedThing	4-aminobutyrate transaminase complex	A homodimeric protein complex that possesses 4-aminobutyrate transaminase activity.	tmpzr1t_l9r_go_relaxed.owl	GABA-T complex|GABA transaminase complex|ABAT complex													cellular_component											owl:Class	
GO:1990867	biolink:NamedThing	response to gastrin	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gastrin stimulus.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-09-25T16:22:39Z					biological_process											owl:Class	
GO:0047178	biolink:NamedThing	glycerophospholipid acyltransferase (CoA-dependent) activity	Catalysis of the reaction: 1-radyl-2-lyso-sn-glycero-3-phosphoethanolamine + 1-radyl-2-acyl-sn-glycero-3-phosphocholine = 1-radyl-2-lyso-sn-glycero-3-phosphocholine + 1-radyl-2-acyl-sn-glycero-3-phosphoethanolamine.	tmpzr1t_l9r_go_relaxed.owl	1-organyl-2-acyl-sn-glycero-3-phosphocholine:1-organyl-2-lyso-sn-glycero-3-phosphoethanolamine acyltransferase (CoA-dependent)				MetaCyc:2.3.1.148-RXN|RHEA:20972|EC:2.3.1.148									molecular_function											owl:Class	
GO:0102040	biolink:NamedThing	fumarate reductase (menaquinone)	Catalysis of the reaction: fumarate + a menaquinol = succinate + a menaquinone.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:R601-RXN|RHEA:27834|EC:1.3.5.4									molecular_function											owl:Class	
GO:0070482	biolink:NamedThing	response to oxygen levels	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of oxygen.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0060998	biolink:NamedThing	regulation of dendritic spine development	Any process that modulates the rate, frequency, or extent of dendritic spine development, the process whose specific outcome is the progression of the dendritic spine over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-01-20T09:17:06Z					biological_process											owl:Class	
GO:0120060	biolink:NamedThing	regulation of gastric emptying	Any process that modulates the frequency, rate or extent of any gastric emptying process, the process in which the liquid and liquid-suspended solid contents of the stomach exit through the pylorus into the duodenum.	tmpzr1t_l9r_go_relaxed.owl	regulation of small intestine emptying|regulation of small bowel emptying							krc	2017-06-13T21:47:16Z					biological_process											owl:Class	
GO:1990427	biolink:NamedThing	stereocilia tip-link density	An electron-dense plaque at either end of a stereocilia tip link that provides the anchor in the stereocilia membrane.	tmpzr1t_l9r_go_relaxed.owl								sl	2014-07-25T20:55:36Z					cellular_component											owl:Class	
GO:0045854	biolink:NamedThing	positive regulation of bicoid mRNA localization	Any process that activates or increases the frequency, rate or extent of the process in which bicoid mRNA is transported to, or maintained in, a specific location.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of bicoid mRNA localisation|upregulation of bicoid mRNA localization|up-regulation of bicoid mRNA localization|activation of bicoid mRNA localization|stimulation of bicoid mRNA localization|up regulation of bicoid mRNA localization													biological_process											owl:Class	
GO:1903866	biolink:NamedThing	palisade mesophyll development	The process whose specific outcome is the progression of a palisade mesophyll over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl	palisade parenchyma development							tb	2015-02-04T21:51:44Z					biological_process											owl:Class	
GO:0006202	biolink:NamedThing	GMP catabolic process to guanine	The chemical reactions and pathways resulting in the breakdown of guanosine monophosphate into other compounds, including guanine.	tmpzr1t_l9r_go_relaxed.owl	GMP breakdown to guanine|GMP degradation to guanine													biological_process											owl:Class	
GO:0003947	biolink:NamedThing	(N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase activity	Catalysis of the reaction: UDP-N-acetyl-D-galactosamine + (N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide = UDP + N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide.	tmpzr1t_l9r_go_relaxed.owl	uridine diphosphoacetylgalactosamine-acetylneuraminylgalactosylglucosylceramide acetylgalactosaminyltransferase activity|ganglioside GM3 acetylgalactosaminyltransferase activity|UDP-N-acetylgalactosamine GM3 N-acetylgalactosaminyltransferase activity|UDP-N-acetyl-D-galactosamine:1-O-[O-(N-acetyl-alpha-neuraminosyl)-(2->3)-O-beta-D-galactopyranosyl-(1->4)-beta-D-glucopyranosyl]-ceramide 1,4-beta-N-acetyl-D-galactosaminyltransferase activity|GM2/GD2-synthase activity|ganglioside GM2 synthase activity|UDP-N-acetyl-D-galactosamine:(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide N-acetyl-D-galactosaminyltransferase activity|UDP acetylgalactosamine-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide acetylgalactosaminyltransferase activity|GalNAc-T activity|asialo-GM2 synthase activity|uridine diphosphoacetylgalactosamine-ganglioside GM3 acetylgalactosaminyltransferase activity|beta-1,4N-aetylgalactosaminyltransferase activity|uridine diphosphoacetylgalactosamine-hematoside acetylgalactosaminyltransferase activity|GM2 synthase activity				EC:2.4.1.92|Reactome:R-HSA-8856223|MetaCyc:2.4.1.92-RXN|RHEA:12588									molecular_function											owl:Class	
GO:0002069	biolink:NamedThing	columnar/cuboidal epithelial cell maturation	The developmental process, independent of morphogenetic (shape) change, that is required for a columna/cuboidal epithelial cell to attain its fully functional state. A columnar/cuboidal epithelial cell is a cell usually found in a two dimensional sheet with a free surface. Columnar/cuboidal epithelial cells take on the shape of a column or cube.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0071024	biolink:NamedThing	SL snRNP	A ribonucleoprotein complex that contains spliced leader (SL) RNA and associated proteins.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-07-30T12:00:35Z					cellular_component											owl:Class	
GO:0075069	biolink:NamedThing	adhesion of symbiont infection cushion to host	The attachment of an infection cushion of the symbiont to its host via adhesion molecules. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	adhesion of symbiont infection cushion to host during symbiotic interaction					Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products from the symbiont involved in this process.								biological_process											owl:Class	
GO:0019270	biolink:NamedThing	aerobactin biosynthetic process	The chemical reactions and pathways resulting in the formation of aerobactin (C22H36N4O13), a hydroxamate iron transport compound. It is a conjugate of 6-(N-acetyl-N-hydroxylamine)-2-aminohexanoic acid and citric acid.	tmpzr1t_l9r_go_relaxed.owl	aerobactin anabolism|aerobactin formation|aerobactin biosynthesis|aerobactin synthesis				MetaCyc:AEROBACTINSYN-PWY									biological_process											owl:Class	
GO:0097101	biolink:NamedThing	blood vessel endothelial cell fate specification	The process involved in the specification of identity of a blood vessel endothelial cell. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment. A blood vessel endothelial cell is an endothelial cell of the vascular tree, which includes blood vessels and lymphatic vessels.	tmpzr1t_l9r_go_relaxed.owl								pr	2011-07-27T10:24:32Z					biological_process											owl:Class	
GO:0102620	biolink:NamedThing	3-geranylgeranylindole NADPH:oxygen oxidoreductase (10,11-epoxidizing) activity	Catalysis of the reaction: 3-geranylgeranylindole + O2 + NADPH + H+ = 10,11-epoxy-3-geranylgeranylindole + NADP + H2O.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-15495									molecular_function											owl:Class	
GO:0042488	biolink:NamedThing	positive regulation of odontogenesis of dentin-containing tooth	Any process that activates or increases the frequency, rate or extent of the formation and development of teeth, the hard, bony appendages that are borne on the jaws, or on other bones in the walls of the mouth or pharynx of most vertebrates.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of odontogenesis|positive regulation of odontogenesis of dentine-containing tooth|stimulation of odontogenesis|upregulation of odontogenesis|positive regulation of odontogenesis of dentine-containing teeth|activation of odontogenesis|up regulation of odontogenesis													biological_process											owl:Class	
GO:0042482	biolink:NamedThing	positive regulation of odontogenesis	Any process that activates or increases the frequency, rate or extent of the formation and development of a tooth or teeth.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of tooth development|positive regulation of odontogenesis of calcareous or chitinous tooth|up-regulation of odontogenesis|upregulation of odontogenesis|activation of odontogenesis|stimulation of odontogenesis|up regulation of odontogenesis											GO:0042485		biological_process											owl:Class	
GO:0004512	biolink:NamedThing	inositol-3-phosphate synthase activity	Catalysis of the reaction: D-glucose 6-phosphate = 1D-myo-inositol 3-phosphate. This reaction requires NAD, which dehydrogenates the CHOH group to CO at C-5 of the glucose 6-phosphate, making C-6 into an active methylene, able to condense with the aldehyde at C-1. Finally, the enzyme-bound NADH reconverts C-5 into the CHOH form.	tmpzr1t_l9r_go_relaxed.owl	D-glucose 6-phosphate cycloaldolase activity|inositol 1-phosphate synthatase activity|glucose-6-phosphate inositol monophosphate cycloaldolase activity|glucose 6-phosphate cyclase activity|1L-myo-inositol-1-phosphate lyase (isomerizing)|glucocycloaldolase activity|inositol 1-phosphate synthetase activity				KEGG_REACTION:R07324|MetaCyc:MYO-INOSITOL-1-PHOSPHATE-SYNTHASE-RXN|Reactome:R-HSA-1855178|RHEA:10716|EC:5.5.1.4									molecular_function											owl:Class	
GO:0102144	biolink:NamedThing	carboxyspermidine dehydrogenase II activity	Catalysis of the reaction: carboxyspermidine + H2O + NADP <=> L-aspartic acid 4-semialdehyde betaine + 1,4-butanediammonium + NADPH + H+.	tmpzr1t_l9r_go_relaxed.owl					RHEA:34111|MetaCyc:RXN-11566									molecular_function											owl:Class	
GO:0098715	biolink:NamedThing	malonic acid import across plasma membrane	The directed movement of malonic acid from outside of a cell, across the plasma membrane and into the cytosol.	tmpzr1t_l9r_go_relaxed.owl	malonic acid import into cell|malonate import into cell							pr	2012-10-30T15:33:37Z			GO:0097406		biological_process											owl:Class	
GO:0040005	biolink:NamedThing	chitin-based cuticle attachment to epithelium	Attaching of a chitin-containing cuticle to the epithelium underlying it. An example of this process is found in Drosophila melanogaster.	tmpzr1t_l9r_go_relaxed.owl	cuticular attachment to epithelium													biological_process											owl:Class	
GO:0044728	biolink:NamedThing	DNA methylation or demethylation	The process of adding or removing a methyl group from one or more nucleotides within an DNA molecule.	tmpzr1t_l9r_go_relaxed.owl	changes in DNA methylation							jl	2012-10-24T14:49:41Z					biological_process											owl:Class	
GO:1903970	biolink:NamedThing	negative regulation of response to macrophage colony-stimulating factor	Any process that stops, prevents or reduces the frequency, rate or extent of response to macrophage colony-stimulating factor.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of response to M-CSF|downregulation of response to M-CSF|downregulation of response to macrophage colony-stimulating factor|negative regulation of response to macrophage colony-stimulating factor stimulus|negative regulation of response to M-CSF|down regulation of response to macrophage colony-stimulating factor stimulus|down regulation of response to M-CSF|down-regulation of response to macrophage colony-stimulating factor stimulus|inhibition of response to macrophage colony-stimulating factor|inhibition of response to M-CSF|down-regulation of response to macrophage colony-stimulating factor|downregulation of response to macrophage colony-stimulating factor stimulus|inhibition of response to macrophage colony-stimulating factor stimulus|down regulation of response to macrophage colony-stimulating factor							nc	2015-03-02T14:41:08Z					biological_process											owl:Class	
GO:0008919	biolink:NamedThing	lipopolysaccharide glucosyltransferase I activity	Catalysis of the reaction: UDP-glucose + lipopolysaccharide = UDP + D-glucosyl-lipopolysaccharide.	tmpzr1t_l9r_go_relaxed.owl	lipopolysaccharide glucosyltransferase activity|uridine diphosphoglucose-lipopolysaccharide glucosyltransferase activity|uridine diphosphate glucose:lipopolysaccharide glucosyltransferase I|UDP-glucose:lipopolysaccharide glucosyltransferase activity|UDPglucose:lipopolysaccharide glucosyltransferase activity|LPS glucosyltransferase I activity|UDPglucose:lipopolysaccharide glucosyltransferase I				MetaCyc:2.4.1.58-RXN|EC:2.4.1.58									molecular_function											owl:Class	
GO:0002810	biolink:NamedThing	regulation of antifungal peptide biosynthetic process	Any process that modulates the frequency, rate, or extent of antifungal peptide biosynthesis.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0030688	biolink:NamedThing	preribosome, small subunit precursor	A preribosomal complex consisting of 20S pre-rRNA, ribosomal proteins including late-associating small subunit proteins, and associated proteins; a precursor of the eukaryotic cytoplasmic small ribosomal subunit.	tmpzr1t_l9r_go_relaxed.owl	43S preribosome					Note that this complex is 43S in Saccharomyces.								cellular_component											owl:Class	
GO:0070770	biolink:NamedThing	alphaIIb-beta3 integrin-CD47-FAK complex	A protein complex that consists of an alphaIIb-beta3 integrin complex bound to the cell surface antigen CD47 and the kinase FAK.	tmpzr1t_l9r_go_relaxed.owl	ITGA2b-ITGB3-CD47-FAK complex							mah	2009-06-29T05:43:59Z					cellular_component											owl:Class	
GO:0045218	biolink:NamedThing	zonula adherens maintenance	Maintaining the zonula adherens junction, the cell-cell adherens junction formed near the apex of epithelial cells.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0034846	biolink:NamedThing	naphthyl-2-methylene-succinyl-CoA lyase activity	Catalysis of the reaction: naphthyl-2-methylene-succinyl-CoA + H2O = naphthyl-2-hydroxymethyl-succinyl-CoA.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r1259									molecular_function											owl:Class	
GO:0050571	biolink:NamedThing	1,5-anhydro-D-fructose reductase activity	Catalysis of the reaction: 1,5-anhydro-D-glucitol + NADP(+) = 1,5-anhydro-D-fructose + H(+) + NADPH.	tmpzr1t_l9r_go_relaxed.owl	1,5-anhydro-D-glucitol:NADP+ oxidoreductase activity|AF reductase activity				EC:1.1.1.263|KEGG_REACTION:R05682|MetaCyc:1.1.1.263-RXN|RHEA:20665									molecular_function											owl:Class	
GO:0003914	biolink:NamedThing	DNA (6-4) photolyase activity	Catalysis of the reaction: pyrimidine-pyrimidone (6-4) photoproduct (in DNA) = 2 pyrimidine residues (in DNA). Catalyzes the reactivation of ultraviolet-irradiated DNA.	tmpzr1t_l9r_go_relaxed.owl					EC:4.1.99.13|MetaCyc:RXN-10771									molecular_function											owl:Class	
GO:0042706	biolink:NamedThing	eye photoreceptor cell fate commitment	The process in which the developmental fate of a cell becomes restricted such that it will develop into an eye photoreceptor cell. A photoreceptor cell is a cell that responds to incident electromagnetic radiation. Different classes of photoreceptor have different spectral sensitivities and express different photosensitive pigments.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0043740	biolink:NamedThing	GTP cyclohydrolase IIa activity	Catalysis of the reaction: GTP + 3 H(2)O = 2-amino-5-formylamino-6-(1-D-ribosylamino)pyrimidin-4(3H)-one 5'-phosphate + 3 H(+) + 2 phosphate.	tmpzr1t_l9r_go_relaxed.owl	GTP 8,9-dihydrolase (phosphate-forming)|GTP 8,9-hydrolase (phosphate-forming)|GTP cyclohydrolase III activity				KEGG_REACTION:R07306|EC:3.5.4.29|MetaCyc:RXN-10055|RHEA:22468									molecular_function											owl:Class	
GO:0018857	biolink:NamedThing	2,4-dichlorobenzoate-CoA ligase activity	Catalysis of the reaction: 2,4-dichlorobenzoate + ATP + CoASH = AMP + diphosphate + 2,4-dichlorobenzoyl-CoA.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0137									molecular_function											owl:Class	
GO:0061869	biolink:NamedThing	regulation of hepatic stellate cell migration	Any process that modulates the frequency, rate or extent of hepatic stellate cell migration.	tmpzr1t_l9r_go_relaxed.owl								dph	2017-05-01T13:04:20Z					biological_process											owl:Class	
GO:0090613	biolink:NamedThing	5'-deoxyadenosine deaminase activity	Catalysis of the reaction: 5'deoxyadenosine + H2O = 5'deoxyinosine + NH3.	tmpzr1t_l9r_go_relaxed.owl					EC:3.5.4.41|RHEA:42892			tb	2014-10-23T15:59:38Z					molecular_function											owl:Class	
GO:1902291	biolink:NamedThing	cell cycle DNA replication DNA ligation	Any DNA ligation that is involved in cell cycle DNA replication.	tmpzr1t_l9r_go_relaxed.owl	DNA ligation involved in cell cycle DNA replication							jl	2013-07-09T16:05:45Z					biological_process											owl:Class	
GO:0016643	biolink:NamedThing	oxidoreductase activity, acting on the CH-NH2 group of donors, iron-sulfur protein as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH2 group acts as a hydrogen or electron donor and reduces an iron-sulfur protein.	tmpzr1t_l9r_go_relaxed.owl	oxidoreductase activity, acting on the CH-NH2 group of donors, iron-sulphur protein as acceptor				EC:1.4.7.-									molecular_function											owl:Class	
GO:0031624	biolink:NamedThing	ubiquitin conjugating enzyme binding	Binding to a ubiquitin conjugating enzyme, any of the E2 proteins.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0044390	biolink:NamedThing	ubiquitin-like protein conjugating enzyme binding	Binding to a ubiquitin-like protein conjugating enzyme such as ubiquitin conjugating enzyme.	tmpzr1t_l9r_go_relaxed.owl	small protein conjugating enzyme binding|E2 protein ligase binding							jl	2011-12-15T04:38:44Z					molecular_function											owl:Class	
GO:0046285	biolink:NamedThing	flavonoid phytoalexin metabolic process	The chemical reactions and pathways involving flavonoid phytoalexins, a group of water-soluble phenolic derivatives containing a flavan skeleton, which possess antibiotic activity and are produced by plant tissues in response to infection.	tmpzr1t_l9r_go_relaxed.owl	flavonoid phytoalexin metabolism													biological_process											owl:Class	
GO:0035234	biolink:NamedThing	ectopic germ cell programmed cell death	Programmed cell death of an errant germ line cell that is outside the normal migratory path or ectopic to the gonad. This is an important mechanism of regulating germ cell survival within the embryo.	tmpzr1t_l9r_go_relaxed.owl	programmed cell death of ectopic germ cells|programmed cell death, ectopic germ cells													biological_process											owl:Class	
GO:0140432	biolink:NamedThing	5'-hydroxyl dinucleotide hydrolase	Catalysis of the hydrolysis of phosphodiester bonds in 5'OH-RNA according to the reaction 5'OH-RNA + H20 = 5'OH-NpN (dinucleotide) + 5'P-RNA.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/18881						pg	2020-02-19T05:50:35Z					molecular_function											owl:Class	
GO:0019280	biolink:NamedThing	L-methionine biosynthetic process from homoserine via O-acetyl-L-homoserine and cystathionine	The chemical reactions and pathways resulting in the formation of methionine from other compounds, including homoserine, via the intermediates O-acetyl-L-homoserine and cystathionine.	tmpzr1t_l9r_go_relaxed.owl	L-methionine synthesis from homoserine via O-acetyl-L-homoserine and cystathionine|L-methionine anabolism from homoserine via O-acetyl-L-homoserine and cystathionine|methionine biosynthetic process from homoserine via O-acetyl-L-homoserine and cystathionine|L-methionine formation from homoserine via O-acetyl-L-homoserine and cystathionine				MetaCyc:HSERMETANA-PWY									biological_process											owl:Class	
GO:0045462	biolink:NamedThing	trichothecene 3-O-acetyltransferase activity	Catalysis of the 3-O-acetylation of a trichothecene. Trichothecenes are sesquiterpene epoxide mycotoxins that act as potent inhibitors of eukaryotic protein synthesis.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0102162	biolink:NamedThing	all-trans-8'-apo-beta-carotenal 15,15'-oxygenase	Catalysis of the reaction: 8'-apo-beta,psi-caroten-8'-al + O2 <=> all-trans-retinal + 2,6-dimethylocta-2,4,6-trienedial.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-11783|EC:1.13.11.75|RHEA:26385									molecular_function											owl:Class	
GO:0052489	biolink:NamedThing	negative regulation by host of symbiont programmed cell death	Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of programmed cell death in a symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	down-regulation by host of symbiont programmed cell death|inhibition by host of symbiont programmed cell death|downregulation by host of symbiont programmed cell death|inhibition of symbiont programmed cell death|down regulation by host of symbiont programmed cell death													biological_process											owl:Class	
GO:1904258	biolink:NamedThing	nuclear dicing body assembly	The aggregation, arrangement and bonding together of a set of components to form a nuclear dicing body.	tmpzr1t_l9r_go_relaxed.owl	nuclear dicing body formation|D body formation|D body assembly							lr	2015-05-20T20:48:07Z					biological_process											owl:Class	
GO:0043635	biolink:NamedThing	methylnaphthalene catabolic process	The chemical reactions and pathways resulting in the breakdown of methylnaphthalene, an organic compound, C10H7CH3, obtained from coal tar.	tmpzr1t_l9r_go_relaxed.owl	1-methylnaphthalene catabolism|1-methylnaphthalene catabolic process|2-methylnaphthalene catabolism|1-MN catabolism|2-MN catabolism|2-MN catabolic process|1-MN catabolic process|2-methylnaphthalene catabolic process													biological_process											owl:Class	
GO:0015284	biolink:NamedThing	fructose uniporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: fructose(out) = fructose(in).	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0140201	biolink:NamedThing	urea import across plasma membrane	The directed movement of urea from outside of a cell, across the plasma membrane and into the cytosol.	tmpzr1t_l9r_go_relaxed.owl								pg	2018-02-20T10:15:45Z					biological_process											owl:Class	
GO:0036377	biolink:NamedThing	arbuscular mycorrhizal association	A form of mutualism between a fungus and the roots of a vascular plant, where hyphae of the fungus penetrate the plant cell wall and invaginate its cell membrane. Once inside, the fungus forms highly branched structures for nutrient exchange with the plant called arbuscules. Aids in the acquisition by the plant of nutrients such as phosphorus from the soil.	tmpzr1t_l9r_go_relaxed.owl	arbuscular mycorrhizal symbiosis|arbuscular mycorrhizas formation|arbuscular mycorrhizae formation							bf	2013-05-07T15:07:32Z					biological_process											owl:Class	
GO:1904638	biolink:NamedThing	response to resveratrol	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a resveratrol stimulus.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-08-31T17:07:38Z					biological_process											owl:Class	
GO:0035634	biolink:NamedThing	response to stilbenoid	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of exposure to a stilbenoid. Stilbenoids are secondary products of heartwood formation in trees that can act as phytoalexins. Stilbenoids are hydroxylated derivatives of stilbene. They belong to the family of phenylpropanoids and share most of their biosynthesis pathway with chalcones.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-01-12T10:37:33Z					biological_process											owl:Class	
GO:1905188	biolink:NamedThing	positive regulation of metaphase/anaphase transition of meiosis I	Any process that activates or increases the frequency, rate or extent of metaphase/anaphase transition of meiosis I.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of meiosis I metaphase/anaphase transition							vw	2016-05-10T16:32:19Z					biological_process											owl:Class	
GO:0047870	biolink:NamedThing	discadenine synthase activity	Catalysis of the reaction: N(6)-dimethylallyladenine + S-adenosyl-L-methionine(1+) = S-methyl-5'-thioadenosine + discadenine + H(+).	tmpzr1t_l9r_go_relaxed.owl	S-adenosyl-L-methionine:N6-(Delta2-isopentenyl)-adenine 3-(3-amino-3-carboxypropyl)-transferas|discadenine synthetase activity|S-adenosyl-L-methionine:6-N-(Delta2-isopentenyl)-adenine 3-(3-amino-3-carboxypropyl)-transferase activity				KEGG_REACTION:R03726|RHEA:19581|MetaCyc:DISCADENINE-SYNTHASE-RXN|EC:2.5.1.24									molecular_function											owl:Class	
GO:0035662	biolink:NamedThing	Toll-like receptor 4 binding	Binding to a Toll-like 4 protein, a pattern recognition receptor that binds bacterial lipopolysaccharide (LPS) to initiate an innate immune response.	tmpzr1t_l9r_go_relaxed.owl	TLR4 binding							bf	2011-02-01T10:20:59Z					molecular_function											owl:Class	
GO:0035325	biolink:NamedThing	Toll-like receptor binding	Binding to a Toll-like protein, a pattern recognition receptor that binds pattern motifs from a variety of microbial sources to initiate an innate immune response.	tmpzr1t_l9r_go_relaxed.owl	TLR binding							bf	2010-02-26T10:11:55Z					molecular_function											owl:Class	
GO:1905480	biolink:NamedThing	positive regulation of glutamate-ammonia ligase activity	Any process that activates or increases the frequency, rate or extent of glutamate-ammonia ligase activity.	tmpzr1t_l9r_go_relaxed.owl	upregulation of glutamine synthetase activity|up regulation of glutamate-ammonia ligase activity|up-regulation of L-glutamine synthetase activity|activation of L-glutamine synthetase activity|activation of glutamine synthetase activity|up-regulation of L-glutamate:ammonia ligase (ADP-forming)|activation of glutamylhydroxamic synthetase activity|positive regulation of L-glutamate:ammonia ligase (ADP-forming)|up-regulation of glutamylhydroxamic synthetase activity|positive regulation of L-glutamine synthetase activity|activation of L-glutamate:ammonia ligase (ADP-forming)|upregulation of glutamate-ammonia ligase activity|up-regulation of glutamine synthetase activity|up regulation of glutamylhydroxamic synthetase activity|up-regulation of glutamate-ammonia ligase activity|upregulation of L-glutamine synthetase activity|up regulation of glutamine synthetase activity|up regulation of L-glutamine synthetase activity|upregulation of glutamylhydroxamic synthetase activity|positive regulation of glutamine synthetase activity|activation of glutamate-ammonia ligase activity|upregulation of L-glutamate:ammonia ligase (ADP-forming)|positive regulation of glutamylhydroxamic synthetase activity|up regulation of L-glutamate:ammonia ligase (ADP-forming)							pga	2016-09-22T09:58:50Z					biological_process											owl:Class	
GO:0017045	biolink:NamedThing	corticotropin-releasing hormone activity	The action characteristic of corticotropin-releasing hormone (CRH), any of a number of peptides released by the mammalian hypothalamus into the hypophyseal-portal circulation in response to neural and/or chemical stimuli. Upon receptor binding, CRH increases the rate of corticotropin secretion by the anterior pituitary.	tmpzr1t_l9r_go_relaxed.owl	adrenocorticotropin-releasing hormone				Wikipedia:Corticotropin-releasing_hormone									molecular_function											owl:Class	
GO:1990817	biolink:NamedThing	RNA adenylyltransferase activity	Catalysis of the template-independent extension of the 3'- end of an RNA strand by addition of one adenosine molecule at a time. Cannot initiate a chain 'de novo'. The primer, depending on the source of the enzyme, may be an RNA, or oligo(A) bearing a 3'-OH terminal group.	tmpzr1t_l9r_go_relaxed.owl								vw	2015-07-31T09:38:31Z					molecular_function											owl:Class	
GO:0016077	biolink:NamedThing	sno(s)RNA catabolic process	The chemical reactions and pathways resulting in the breakdown of snoRNA, small nucleolar RNA, any of a class of small RNAs that are associated with the eukaryotic nucleus as components of small nucleolar ribonucleoproteins.	tmpzr1t_l9r_go_relaxed.owl	sno(s)RNA catabolism|sno(s)RNA breakdown|sno(s)RNA degradation|sRNA catabolic process|snoRNA catabolic process	https://github.com/geneontology/go-ontology/issues/20416												biological_process											owl:Class	
GO:0098983	biolink:NamedThing	symmetric, GABA-ergic, inhibitory synapse	A neuron to neuron synapse that lacks an electron dense postsynaptic specialization, uses GABA as a neurotransmitter and whose activity results in inhibitory postsynaptic potentials.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:1990013	biolink:NamedThing	presynaptic grid	A hexagonal array of electron dense particles attached to the cytoplasmic face of the presynaptic membrane.	tmpzr1t_l9r_go_relaxed.owl	pre-synaptic grid				NIF_Subcellular:sao1730664005			pr	2012-12-13T09:00:35Z					cellular_component											owl:Class	
GO:0009504	biolink:NamedThing	cell plate	The nascent cell membrane and cell wall structure that forms between two daughter nuclei near the center of a dividing plant cell. It develops at the equitorial region of the phragmoplast. It grows outwards to join with the lateral walls and form two daughter cells.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Cell_plate									cellular_component											owl:Class	
GO:0021521	biolink:NamedThing	ventral spinal cord interneuron specification	The process in which a cell becomes capable of differentiating autonomously into a ventral spinal cord interneuron in an environment that is neutral with respect to the developmental pathway.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:2000389	biolink:NamedThing	regulation of neutrophil extravasation	Any process that modulates the frequency, rate or extent of neutrophil extravasation.	tmpzr1t_l9r_go_relaxed.owl								mah	2011-02-22T11:07:58Z					biological_process											owl:Class	
GO:1902622	biolink:NamedThing	regulation of neutrophil migration	Any process that modulates the frequency, rate or extent of neutrophil migration.	tmpzr1t_l9r_go_relaxed.owl								sl	2014-01-15T18:58:39Z					biological_process											owl:Class	
GO:0071708	biolink:NamedThing	immunoglobulin light chain V-J recombination	The process in which immunoglobulin light chain V and J gene segments are recombined within a single locus utilizing the conserved heptamer and nonomer recombination signal sequences (RSS).	tmpzr1t_l9r_go_relaxed.owl	immunoglobulin V(D)J joining|immunoglobulin V(D)J recombination|immunoglobulin V-J joining							mah	2010-03-09T04:22:29Z					biological_process											owl:Class	
GO:0033152	biolink:NamedThing	immunoglobulin V(D)J recombination	The process in which immunoglobulin gene segments are recombined within a single locus utilizing the conserved heptamer and nonomer recombination signal sequences (RSS). For immunoglobulin heavy chains V, D, and J gene segments are joined, and for immunoglobulin light chains V and J gene segments are joined.	tmpzr1t_l9r_go_relaxed.owl	immunoglobulin V-D-J recombination|immunoglobulin V-J recombination|immunoglobulin V-J joining|immunoglobulin V-D-J joining|immunoglobulin V(D)J joining													biological_process											owl:Class	
GO:1904951	biolink:NamedThing	positive regulation of establishment of protein localization	Any process that activates or increases the frequency, rate or extent of establishment of protein localization.	tmpzr1t_l9r_go_relaxed.owl	upregulation of establishment of protein localisation|upregulation of protein positioning|up-regulation of protein recruitment|activation of protein recruitment|up-regulation of establishment of protein localisation|activation of establishment of protein localisation|upregulation of establishment of protein localization|positive regulation of protein recruitment|activation of protein positioning|positive regulation of establishment of protein localisation|activation of establishment of protein localization|up regulation of establishment of protein localization|up regulation of protein recruitment|up-regulation of establishment of protein localization|positive regulation of protein positioning|up regulation of protein positioning|upregulation of protein recruitment|up-regulation of protein positioning|up regulation of establishment of protein localisation							mec	2016-02-05T09:59:32Z					biological_process											owl:Class	
GO:0030209	biolink:NamedThing	dermatan sulfate catabolic process	The chemical reactions and pathways resulting in the breakdown of dermatan sulfate, any of a group of glycosaminoglycans with repeats consisting of beta-(1,4)-linked L-iduronyl-beta-(1,3)-N-acetyl-D-galactosamine 4-sulfate units.	tmpzr1t_l9r_go_relaxed.owl	chondroitin sulfate B catabolic process|dermatan sulphate catabolic process|dermatan sulfate catabolism|dermatan sulfate degradation|dermatan sulfate breakdown|dermatan sulphate catabolism|chondroitin sulfate B catabolism													biological_process											owl:Class	
GO:0018012	biolink:NamedThing	N-terminal peptidyl-alanine trimethylation	The trimethylation of the N-terminal alanine of proteins to form the derivative peptidyl-N,N,N-trimethyl-L-alanine.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0062									biological_process											owl:Class	
GO:0018011	biolink:NamedThing	N-terminal peptidyl-alanine methylation	The methylation of the N-terminal alanine of proteins.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0061|RESID:AA0062									biological_process											owl:Class	
GO:0039674	biolink:NamedThing	exit of virus from host cell nucleus	The directed movement of the viral genome or a viral particle out of the host cell nucleus.	tmpzr1t_l9r_go_relaxed.owl					VZ:2177			bf	2013-09-25T13:59:41Z					biological_process											owl:Class	
GO:0039018	biolink:NamedThing	nephrostome development	The process whose specific outcome is the progression of the nephrostome over time, from its formation to the mature structure. The nephrostome is the opening of the pronephros into the body cavity.	tmpzr1t_l9r_go_relaxed.owl								bf	2010-07-02T10:08:16Z					biological_process											owl:Class	
GO:0004310	biolink:NamedThing	farnesyl-diphosphate farnesyltransferase activity	Catalysis of the reaction: 2 farnesyl diphosphate = diphosphate + presqualene diphosphate.	tmpzr1t_l9r_go_relaxed.owl	farnesyl-diphosphate:farnesyl-diphosphate farnesyltransferase activity|presqualene synthase activity|presqualene-diphosphate synthase activity				Reactome:R-HSA-191402|Reactome:R-HSA-191405|EC:2.5.1.21|MetaCyc:2.5.1.21-RXN	Note that the two reactions performed by EC:2.5.1.21 are represented in GO by 'farnesyl-diphosphate farnesyltransferase activity ; GO:0004310' and 'squalene synthase activity ; GO:0051996'.								molecular_function											owl:Class	
GO:0002934	biolink:NamedThing	desmosome organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a desmosome. A desmosome is a patch-like intercellular junction found in vertebrate tissues, consisting of parallel zones of two cell membranes, separated by an space of 25-35 nm, and having dense fibrillar plaques in the subjacent cytoplasm.	tmpzr1t_l9r_go_relaxed.owl								hjd	2012-05-08T02:59:08Z					biological_process											owl:Class	
GO:0022037	biolink:NamedThing	metencephalon development	The process whose specific outcome is the progression of the metencephalon over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0006057	biolink:NamedThing	mannoprotein biosynthetic process	The chemical reactions and pathways resulting in the formation of a mannoprotein, a protein that contains covalently bound mannose residues.	tmpzr1t_l9r_go_relaxed.owl	mannoprotein anabolism|mannoprotein formation|mannoprotein biosynthesis|mannoprotein synthesis													biological_process											owl:Class	
GO:0008239	biolink:NamedThing	dipeptidyl-peptidase activity	Catalysis of the hydrolysis of N-terminal dipeptides from a polypeptide chain.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/19681			EC:3.4.14.5|EC:3.4.14.1|EC:3.4.14.4|EC:3.4.14.2									molecular_function											owl:Class	
GO:0043916	biolink:NamedThing	DNA-7-methylguanine glycosylase activity	Catalysis of the reaction: DNA containing 7-methylguanine + H2O = DNA with abasic site + 7-methylguanine. This reaction is the hydrolysis of DNA by cleavage of the N-C1' glycosidic bond between the damaged DNA 7-methylguanine and the deoxyribose sugar to remove the 7-methylguanine, leaving an abasic site.	tmpzr1t_l9r_go_relaxed.owl					EC:3.2.2.21|MetaCyc:3.2.2.21-RXN									molecular_function											owl:Class	
GO:0030950	biolink:NamedThing	establishment or maintenance of actin cytoskeleton polarity	Any cellular process that results in the specification, formation or maintenance of polarized actin-based cytoskeletal structures.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1990102	biolink:NamedThing	DnaA-DiaA complex	A protein-DNA complex containing a tetramer of DiaA attached to multiple  DnaA molecule bound to oriC DNA. Regulates timely initiation of chromosomal replication during the cell cycle by stimulating assembly of DnaA-oriC complexes, conformational changes in ATP-DnaA initiation complexes, and unwinding of oriC duplex DNA.	tmpzr1t_l9r_go_relaxed.owl	DnaA-DiaA-DNA complex							bhm	2013-05-14T12:33:59Z					cellular_component											owl:Class	
GO:0061072	biolink:NamedThing	iris morphogenesis	The process in which the iris is generated and organized. The iris is an anatomical structure in the eye whose opening forms the pupil. The iris is responsible for controlling the diameter and size of the pupil and the amount of light reaching the retina.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-03-16T10:48:42Z					biological_process											owl:Class	
GO:0120182	biolink:NamedThing	regulation of focal adhesion disassembly	Any process that modulates the frequency, rate or extent of disaggregation of a focal adhesion into its constituent components.	tmpzr1t_l9r_go_relaxed.owl								krc	2018-07-12T17:44:29Z					biological_process											owl:Class	
GO:0061275	biolink:NamedThing	mesonephric proximal tubule development	The progression of the mesonephric proximal tubule over time, from its formation to the mature structure. The mesonephric proximal tubule extends from the capsule to the distal tubule.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-09-02T01:08:05Z					biological_process											owl:Class	
GO:1990873	biolink:NamedThing	intrinsic component of plasma membrane of cell tip	The component of the plasma membrane surrounding the cell tip consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the plasma membrane surrounding the cell tip or some other covalently attached group such as a GPI anchor that is similarly embedded in the plasma membrane surrounding the cell tip.	tmpzr1t_l9r_go_relaxed.owl								al	2015-09-29T10:06:25Z					cellular_component											owl:Class	
GO:0042978	biolink:NamedThing	ornithine decarboxylase activator activity	Binds to and increases ornithine decarboxylase activity.	tmpzr1t_l9r_go_relaxed.owl	L-ornithine carboxy-lyase activator activity													molecular_function											owl:Class	
GO:0003213	biolink:NamedThing	cardiac right atrium morphogenesis	The process in which the right cardiac atrium is generated and organized.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-10-13T09:49:03Z					biological_process											owl:Class	
GO:0036382	biolink:NamedThing	flavin reductase (NADH) activity	Catalysis of the reaction: reduced flavin + NAD+ = flavin + NADH + H+.	tmpzr1t_l9r_go_relaxed.owl	flavin:NADH oxidoreductase activity|NADH-dependent flavin reductase activity				RHEA:31303|MetaCyc:1.5.1.36-RXN|KEGG_REACTION:R09662|EC:1.5.1.36			bf	2013-05-23T11:23:09Z					molecular_function											owl:Class	
GO:1904378	biolink:NamedThing	maintenance of unfolded protein involved in ERAD pathway	Maintaining an endoplasmic reticulum (ER) protein in an unfolded, soluble state that contributes to its degradation by the cytoplasmic proteasome. Maintaining ER-resident proteins in an unfolded yet soluble state condition after their retro-translocation favors their turnover by the cytosolic proteasome.	tmpzr1t_l9r_go_relaxed.owl	ERAD chaperone-like activity|maintenance of unfolded protein during ERAD|maintenance of unfolded protein involved in endoplasmic reticulum-associated protein degradation pathway|maintenance of unfolded protein involved in ER-associated degradation pathway|chaperone holdase activity|maintenance of unfolded protein involved in endoplasmic reticulum-associated degradation|holdase activity							bf	2015-06-23T09:21:53Z					biological_process											owl:Class	
GO:0036506	biolink:NamedThing	maintenance of unfolded protein	Maintaining a protein in an unfolded, soluble state.	tmpzr1t_l9r_go_relaxed.owl								bf	2015-06-11T10:17:36Z					biological_process											owl:Class	
GO:1905232	biolink:NamedThing	cellular response to L-glutamate	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-glutamate(1-) stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to L-glutamate(1-)							sl	2016-06-07T17:30:08Z					biological_process											owl:Class	
GO:1902065	biolink:NamedThing	response to L-glutamate	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an L-glutamate stimulus.	tmpzr1t_l9r_go_relaxed.owl								tb	2013-04-16T21:21:14Z					biological_process											owl:Class	
GO:1904583	biolink:NamedThing	response to polyamine macromolecule	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a polyamine macromolecule stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to polyamine|response to polyamines							sl	2015-08-20T14:35:26Z					biological_process											owl:Class	
GO:0010493	biolink:NamedThing	Lewis a epitope biosynthetic process	The chemical reactions and pathways resulting in the formation of a Lewis a epitope, a trisaccharide (Fuc-alpha-(1->4)[Gal-beta-(1->3)]GlcNAc) characteristic of plant protein N-linked oligosaccharides.	tmpzr1t_l9r_go_relaxed.owl	LE A biosynthetic process													biological_process											owl:Class	
GO:0103042	biolink:NamedThing	4-hydroxy-L-threonine aldolase activity	Catalysis of the reaction: 4-hydroxy-L-threonine <=> glycolaldehyde + glycine.	tmpzr1t_l9r_go_relaxed.owl					RHEA:28779|MetaCyc:RXN0-6563									molecular_function											owl:Class	
GO:1990273	biolink:NamedThing	snRNA 5'-end processing	Any process involved in forming the mature 5' end of an snRNA molecule.	tmpzr1t_l9r_go_relaxed.owl								al	2014-01-15T15:32:06Z					biological_process											owl:Class	
GO:0035382	biolink:NamedThing	sterol transmembrane transport	The process in which a sterol is transported across a membrane. Sterols are steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule.	tmpzr1t_l9r_go_relaxed.owl	sterol membrane transport					Note that this term is not intended for use in annotating lateral movement within membranes.		bf	2010-03-18T01:24:39Z					biological_process											owl:Class	
GO:1900741	biolink:NamedThing	regulation of filamentous growth of a population of unicellular organisms in response to pH	Any process that modulates the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to pH.	tmpzr1t_l9r_go_relaxed.owl								di	2012-05-28T02:34:39Z					biological_process											owl:Class	
GO:0043259	biolink:NamedThing	laminin-10 complex	A laminin complex composed of alpha5, beta1 and gamma1 polypeptide chains.	tmpzr1t_l9r_go_relaxed.owl	laminin-511 complex													cellular_component											owl:Class	
GO:0038156	biolink:NamedThing	interleukin-3-mediated signaling pathway	A series of molecular signals initiated by the binding of interleukin-3 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.	tmpzr1t_l9r_go_relaxed.owl	interleukin-3-mediated signalling pathway|IL-3-mediated signaling pathway							bf	2012-05-11T11:50:42Z					biological_process											owl:Class	
GO:0043613	biolink:NamedThing	isoprene catabolic process	The chemical reactions and pathways resulting in the breakdown of isoprene, C5H8.	tmpzr1t_l9r_go_relaxed.owl	hemiterpene catabolism|2-methyl-1,3-butadiene catabolic process|hemiterpene catabolic process|2-methyl-1,3-butadiene catabolism													biological_process											owl:Class	
GO:0050552	biolink:NamedThing	(4S)-limonene synthase activity	Catalysis of the reaction: geranyl diphosphate = (4S)-limonene + diphosphate.	tmpzr1t_l9r_go_relaxed.owl	geranyl-diphosphate diphosphate-lyase [cyclizing, (-)-(4S)-limonene-forming]|geranyldiphosphate diphosphate lyase (limonene forming)|geranyldiphosphate diphosphate lyase [cyclizing, (4S)-limonene-forming]|4S-(-)-limonene synthase activity|(-)-(4S)-limonene synthase activity				MetaCyc:4.2.3.16-RXN|EC:4.2.3.16|RHEA:12869									molecular_function											owl:Class	
GO:0120278	biolink:NamedThing	negative regulation of cerebral blood circulation	Any process that stops, prevents or reduces the frequency, rate or extent of cerebral blood circulation.	tmpzr1t_l9r_go_relaxed.owl	downregulation of cerebral blood circulation|negative regulation of cerebrum blood circulation|negative regulation of telencephalon blood circulation|down-regulation of cerebral blood circulation|inhibition of cerebral blood circulation|down regulation of cerebral blood circulation	https://github.com/geneontology/go-ontology/issues/20107						krc	2020-10-21T07:02:05Z					biological_process											owl:Class	
GO:0021977	biolink:NamedThing	tectospinal tract morphogenesis	Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the superior colliculus of the midbrain towards target cells in the ventral spinal cord.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0052814	biolink:NamedThing	medium-chain-aldehyde dehydrogenase activity	Catalysis of the reaction: a medium-chain aldehyde + NAD+ = a medium-chain carboxylate + NADH + H+. Medium-chain aldehydes have a chain length of between 8 and 12 carbons.	tmpzr1t_l9r_go_relaxed.owl	medium-chain aliphatic aldehyde dehydrogenase activity|medium-chain fatty aldehyde dehydrogenase activity|medium-chain-aldehyde:NAD+ oxidoreductase activity				EC:1.2.1.-				2011-10-25T03:04:41Z					molecular_function											owl:Class	
GO:0008864	biolink:NamedThing	formyltetrahydrofolate deformylase activity	Catalysis of the reaction: 10-formyltetrahydrofolate + H(2)O = (6S)-5,6,7,8-tetrahydrofolate + formate + H(+).	tmpzr1t_l9r_go_relaxed.owl	formyltetrahydrofolate hydrolase activity|10-formyltetrahydrofolate amidohydrolase activity|formyl-FH(4) hydrolase activity				RHEA:19833|EC:3.5.1.10|MetaCyc:FORMYLTHFDEFORMYL-RXN|KEGG_REACTION:R00944									molecular_function											owl:Class	
GO:1902795	biolink:NamedThing	siRNA-dependent facultative heterochromatin assembly	The assembly of facultative heterochromatin to form a heterochromatin domain, enriched in histone H3 methylated on lysine 9 (H3K9me), by a process mediated by a small interfering RNA.	tmpzr1t_l9r_go_relaxed.owl	HOOD assembly|heterochromatin domain formation|HOOD formation|heterochromatin domain assembly	https://github.com/geneontology/go-ontology/issues/22326						mah	2014-03-24T12:46:56Z					biological_process											owl:Class	
GO:1905836	biolink:NamedThing	response to triterpenoid	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a triterpenoid stimulus.	tmpzr1t_l9r_go_relaxed.owl								sl	2017-01-17T19:37:36Z					biological_process											owl:Class	
GO:0016555	biolink:NamedThing	uridine to cytidine editing	The conversion of a uridine residue to cytosine in an RNA molecule by amination.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0016553	biolink:NamedThing	base conversion or substitution editing	Any base modification or substitution events that result in alterations in the coding potential or structural properties of RNAs as a result of changes in the base-pairing properties of the modified ribonucleoside(s).	tmpzr1t_l9r_go_relaxed.owl	base conversion/substitution editing													biological_process											owl:Class	
GO:0033701	biolink:NamedThing	dTDP-galactose 6-dehydrogenase activity	Catalysis of the reaction: dTDP-D-galactose + 2 NADP+ + H2O = dTDP-D-galacturonate + 2 NADPH + 2 H+.	tmpzr1t_l9r_go_relaxed.owl	dTDPgalactose 6-dehydrogenase activity|thymidine-diphosphate-galactose dehydrogenase activity|dTDP-D-galactose:NADP+ 6-oxidoreductase activity				MetaCyc:DTDP-GALACTOSE-6-DEHYDROGENASE-RXN|RHEA:12396|EC:1.1.1.186									molecular_function											owl:Class	
GO:0018878	biolink:NamedThing	aerobic beta-1,2,3,4,5,6-hexachlorocyclohexane metabolic process	The chemical reactions and pathways involving beta-1,2,3,4,5,6-hexachlorocyclohexane that occur in presence of oxygen.	tmpzr1t_l9r_go_relaxed.owl	aerobic beta-1,2,3,4,5,6-hexachlorocyclohexane metabolism													biological_process											owl:Class	
GO:0018877	biolink:NamedThing	beta-1,2,3,4,5,6-hexachlorocyclohexane metabolic process	The chemical reactions and pathways involving beta-1,2,3,4,5,6-hexachlorocyclohexane, a halogenated organic insecticide that has been used worldwide for agriculture and public health.	tmpzr1t_l9r_go_relaxed.owl	beta-1,2,3,4,5,6-hexachlorocyclohexane metabolism				UM-BBD_pathwayID:hch									biological_process											owl:Class	
GO:0102720	biolink:NamedThing	acetyl-coenzyme A:acetyl alcohol acetyltransferase activity	Catalysis of the reaction: benzyl alcohol + acetyl-CoA = benzyl acetate + coenzyme A.	tmpzr1t_l9r_go_relaxed.owl					RHEA:36147|MetaCyc:RXN-6762|EC:2.3.1.224									molecular_function											owl:Class	
GO:0071271	biolink:NamedThing	1-butanol biosynthetic process	The chemical reactions and pathways resulting in the formation of 1-butanol, an alkyl primary alcohol with the formula C4H10O.	tmpzr1t_l9r_go_relaxed.owl	butanol biosynthetic process|1-butanol biosynthesis|butan-1-ol biosynthetic process|1-butanol anabolism|1-butanol formation|1-butanol synthesis							mah	2009-12-10T10:27:24Z					biological_process											owl:Class	
GO:0050227	biolink:NamedThing	pteridine oxidase activity	Catalysis of the reaction: 2-amino-4-hydroxypteridine + O2 = 2-amino-4,7-dihydroxypteridine + unknown.	tmpzr1t_l9r_go_relaxed.owl	2-amino-4-hydroxypteridine:oxygen oxidoreductase (7-hydroxylating)				EC:1.17.3.1|MetaCyc:PTERIDINE-OXIDASE-RXN|RHEA:12777									molecular_function											owl:Class	
GO:0102852	biolink:NamedThing	1-18:3-2-16:0-phosphatidylglycerol desaturase activity	Catalysis of the reaction: 1-18:3-2-16:0-phosphatidylglycerol + O2 + a reduced electron acceptor <=> 1-18:3-2-trans-16:1-phosphatidylglycerol + 2 H2O + an oxidized electron acceptor.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-8319									molecular_function											owl:Class	
GO:0060707	biolink:NamedThing	trophoblast giant cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a trophoblast giant cell of the placenta. Trophoblast giant cells are the cell of the placenta that line the maternal decidua.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-06-09T10:32:12Z					biological_process											owl:Class	
GO:0002487	biolink:NamedThing	antigen processing and presentation of endogenous peptide antigen via MHC class I via endolysosomal pathway	The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class I protein complex. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell and becomes associated with the MHC class I molecule in an endolysosome. Class I here refers to classical class I molecules.	tmpzr1t_l9r_go_relaxed.owl	endogenous peptide antigen processing and presentation via MHC class I via endolysosomal pathway													biological_process											owl:Class	
GO:0003436	biolink:NamedThing	regulation of cell adhesion involved in growth plate cartilage morphogenesis	Any process that modulates the frequency, rate or extent of attachment of a cell to another cell or to the extracellular matrix and contributes to the shaping of the growth plate cartilage of an endochondral bone.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-12-22T01:28:15Z					biological_process											owl:Class	
GO:0035503	biolink:NamedThing	ureter part of ureteric bud development	The development of the portion of the ureteric bud that contributes to the morphogenesis of the ureter. The ureter ureteric bud is the initial structure that forms the ureter.	tmpzr1t_l9r_go_relaxed.owl								bf	2010-04-29T03:23:42Z					biological_process											owl:Class	
GO:0010144	biolink:NamedThing	pyridoxal phosphate biosynthetic process from pyridoxamine	The chemical reactions and pathways resulting in the formation of pyridoxal phosphate, the active form of vitamin B6, from pyridoxamine.	tmpzr1t_l9r_go_relaxed.owl	vitamin B6 biosynthesis from pyridoxamine|pyridoxal 5'-phosphate salvage from pyridoxamine|pyridoxal phosphate anabolism from pyridoxamine|pyridoxal phosphate synthesis from pyridoxamine|vitamin B6 biosynthetic process from pyridoxamine|pyridoxal phosphate formation from pyridoxamine													biological_process											owl:Class	
GO:1990263	biolink:NamedThing	spore wall assembly MAPK cascade	A MAPK cascade that occurs as a result of deprivation of nourishment.	tmpzr1t_l9r_go_relaxed.owl	MAPK cascade involved in nutrient response signaling|MAPK cascade in response to starvation							al	2014-01-09T12:27:52Z					biological_process											owl:Class	
GO:0075322	biolink:NamedThing	regulation of oomycete sporangium development	Any process that modulates the frequency, rate or extent of oomycete sporangium development, a process that leads to the formation of oomycete sporangium, a single-celled or many-celled structure that germinates directly to form an infection hypha or differentiate, through specialized cleavage vesicles, into between 10 and 30 zoospores, which is laterally flagellated.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1903001	biolink:NamedThing	negative regulation of lipid transport across blood-brain barrier	Any process that stops, prevents or reduces the frequency, rate or extent of lipid transport across blood-brain barrier.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of lipid transport across blood brain barrier|downregulation of lipid transport across blood brain barrier|down regulation of lipid transport across blood brain barrier|down-regulation of lipid transport across blood brain barrier|inhibition of lipid transport across blood brain barrier							sjp	2014-05-09T09:30:10Z					biological_process											owl:Class	
GO:0005744	biolink:NamedThing	TIM23 mitochondrial import inner membrane translocase complex	The protein transport machinery of the mitochondrial inner membrane that typically transports proteins that possess a matrix-targeting N-terminal presequence. The TIM23 complex contains three essential Tim proteins: Tim17 and Tim23 are thought to build a preprotein translocation channel while Tim44 interacts transiently with the matrix heat-shock protein Hsp70 to form an ATP-driven import motor.	tmpzr1t_l9r_go_relaxed.owl	mitochondrial inner membrane translocase complex|Tim23 complex|mitochondrial inner membrane presequence translocase complex|mitochondrial inner membrane pre-sequence translocase complex					See also the cellular component term 'mitochondrial inner membrane ; GO:0005743'.								cellular_component											owl:Class	
GO:0033345	biolink:NamedThing	asparagine catabolic process via L-aspartate	The chemical reactions and pathways resulting in the breakdown of glutamate, via the intermediate L-aspartate.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:ASPARAGINE-DEG1-PWY									biological_process											owl:Class	
GO:1901008	biolink:NamedThing	(S)-scoulerine catabolic process	The chemical reactions and pathways resulting in the breakdown of (S)-scoulerine.	tmpzr1t_l9r_go_relaxed.owl	(S)-scoulerine catabolism|(S)-scoulerine degradation|(S)-scoulerine breakdown							yaf	2012-06-15T10:46:10Z					biological_process											owl:Class	
GO:1901007	biolink:NamedThing	(S)-scoulerine metabolic process	The chemical reactions and pathways involving (S)-scoulerine.	tmpzr1t_l9r_go_relaxed.owl	(S)-scoulerine metabolism							yaf	2012-06-15T10:45:48Z					biological_process											owl:Class	
GO:0075522	biolink:NamedThing	IRES-dependent viral translational initiation	Process by which viral mRNA translation is initiated, where a domain in the 5' untranslated region (UTR) of the viral mRNA called an internal ribosome entry site (IRES) binds the host 43S preinitiation complex, circumventing regular cap-dependent translation initiation.	tmpzr1t_l9r_go_relaxed.owl					VZ:867			jl	2011-08-03T02:25:03Z					biological_process											owl:Class	
GO:0061525	biolink:NamedThing	hindgut development	The process whose specific outcome is the progression of the hindgut over time, from its formation to the mature structure. The hindgut is part of the alimentary canal that lies posterior to the midgut.	tmpzr1t_l9r_go_relaxed.owl								dph	2013-06-14T11:22:21Z					biological_process											owl:Class	
GO:0101011	biolink:NamedThing	inositol 1-diphosphate 2,3,4,5,6-pentakisphosphate 1-diphosphatase activity	Catalysis of the reaction: myo-inositol 1-diphosphate 2,3,4,5,6-pentakisphosphate + H2O = myo-inositol hexakisphosphate + phosphate.	tmpzr1t_l9r_go_relaxed.owl	inositol 1-pyrophosphate 2,3,4,5,6-pentakisphosphate 1-pyrophosphatase activity													molecular_function											owl:Class	
GO:0072746	biolink:NamedThing	cellular response to tetracycline	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tetracycline stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2012-08-31T12:32:43Z					biological_process											owl:Class	
GO:0004821	biolink:NamedThing	histidine-tRNA ligase activity	Catalysis of the reaction: ATP + L-histidine + tRNA(His) = AMP + diphosphate + L-histidyl-tRNA(His).	tmpzr1t_l9r_go_relaxed.owl	histidyl-transfer ribonucleate synthetase activity|histidine translase activity|histidyl-tRNA synthetase activity|L-histidine:tRNAHis ligase (AMP-forming)				RHEA:17313|Reactome:R-HSA-380234|MetaCyc:HISTIDINE--TRNA-LIGASE-RXN|Reactome:R-HSA-379844|EC:6.1.1.21									molecular_function											owl:Class	
GO:0021641	biolink:NamedThing	trochlear nerve structural organization	The process that contributes to the act of creating the structural organization of the trochlear nerve. This process pertains to the physical shaping of a rudimentary structure. The trochlear nerve is a motor nerve and is the only cranial nerve to exit the brain dorsally. The trochlear nerve innervates the superior oblique muscle.	tmpzr1t_l9r_go_relaxed.owl	trochlear nerve structural organisation|CN IV structural organization													biological_process											owl:Class	
GO:0018295	biolink:NamedThing	protein-FAD linkage via 3'-(8alpha-FAD)-L-histidine	The formation of a protein-FAD linkage via 3'-(8-alpha-FAD)-L-histidine.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0144									biological_process											owl:Class	
GO:0016072	biolink:NamedThing	rRNA metabolic process	The chemical reactions and pathways involving rRNA, ribosomal RNA, a structural constituent of ribosomes.	tmpzr1t_l9r_go_relaxed.owl	rRNA metabolism													biological_process											owl:Class	
GO:0048386	biolink:NamedThing	positive regulation of retinoic acid receptor signaling pathway	Any process that activates or increases the frequency, rate or extent of retinoic acid receptor signaling pathway activity.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of retinoic acid receptor signalling pathway|activation of retinoic acid receptor signaling pathway|stimulation of retinoic acid receptor signaling pathway|upregulation of retinoic acid receptor signaling pathway|up-regulation of retinoic acid receptor signaling pathway|positive regulation of RAR signaling pathway|up regulation of retinoic acid receptor signaling pathway													biological_process											owl:Class	
GO:0008349	biolink:NamedThing	MAP kinase kinase kinase kinase activity	Catalysis of the phosphorylation of serine and threonine residues in a mitogen-activated protein kinase kinase kinase (MAPKKK), resulting in activation of MAPKKK. MAPKKK signaling pathways relay, amplify and integrate signals from the plasma membrane to the nucleus in response to a diverse range of extracellular stimuli.	tmpzr1t_l9r_go_relaxed.owl	MAP4K activity|MAPKKKK				Reactome:R-HSA-177692|Reactome:R-HSA-9645442|Reactome:R-HSA-936991									molecular_function											owl:Class	
GO:0048294	biolink:NamedThing	negative regulation of isotype switching to IgE isotypes	Any process that stops, prevents, or reduces the frequency, rate or extent of isotype switching to IgE isotypes.	tmpzr1t_l9r_go_relaxed.owl	down regulation of isotype switching to IgE isotypes|down-regulation of isotype switching to IgE isotypes|inhibition of isotype switching to IgE isotypes|negative regulation of isotype switch recombination to IgE isotypes|negative regulation of class switching to IgE isotypes|negative regulation of class switch recombination to IgE isotypes|downregulation of isotype switching to IgE isotypes													biological_process											owl:Class	
GO:0042550	biolink:NamedThing	photosystem I stabilization	The stabilization of the photosystem I protein complex, resulting from the phosphorylation of its structural protein subunits, in a cell actively involved in photosynthesis.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0052907	biolink:NamedThing	23S rRNA (adenine(1618)-N(6))-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + adenine(1618) in 23S rRNA = S-adenosyl-L-homocysteine + rRNA containing N(6)-methyladenine(1618) in 23S rRNA.	tmpzr1t_l9r_go_relaxed.owl	M(6)A(1618) activity|rRNA large subunit methyltransferase F activity				KEGG_REACTION:R07232|EC:2.1.1.181|RHEA:16497|MetaCyc:RXN-11596									molecular_function											owl:Class	
GO:0061414	biolink:NamedThing	positive regulation of transcription from RNA polymerase II promoter by a nonfermentable carbon source	A transcription regulation process in which the presence of a nonfermentable carbon source leads to an increase of the frequency, rate, or extent of transcription, from an RNA polymerase II promoter, of specific genes involved in the metabolism of other carbon sources.	tmpzr1t_l9r_go_relaxed.owl								dph	2012-01-23T11:31:27Z					biological_process											owl:Class	
GO:0075185	biolink:NamedThing	positive regulation of infection cushion formation	Any process that activates or increases the frequency, rate or extent of symbiont infection cushion formation on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of infection cushion formation on or near host													biological_process											owl:Class	
GO:0015920	biolink:NamedThing	lipopolysaccharide transport	The directed movement of lipopolysaccharides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A lipopolysaccharide is any of a group of related, structurally complex components of the outer membrane of Gram-negative bacteria. Lipopolysaccharides consist three covalently linked regions, lipid A, core oligosaccharide, and an O side chain. Lipid A is responsible for the toxicity of the lipopolysaccharide.	tmpzr1t_l9r_go_relaxed.owl	LPS transport													biological_process											owl:Class	
GO:0000225	biolink:NamedThing	N-acetylglucosaminylphosphatidylinositol deacetylase activity	Catalysis of the reaction: N-acetyl-D-glucosaminylphosphatidylinositol + H2O = D-glucosaminylphosphatidylinositol + acetate. This reaction is the second step of the biosynthesis of glycosylphosphatidylinositol (GPI), used to anchor various eukaryotic proteins to the cell-surface membrane.	tmpzr1t_l9r_go_relaxed.owl	acetylglucosaminylphosphatidylinositol deacetylase activity|GlcNAc-PI deacetylase activity|GlcNAc-PI de-N-acetylase activity|6-(N-acetyl-alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol acetylhydrolase activity|N-acetylglucosaminylphosphatidylinositol de-N-acetylase activity|N-acetyl-D-glucosaminylphosphatidylinositol acetylhydrolase activity				RHEA:11660|Reactome:R-HSA-162857|EC:3.5.1.89|MetaCyc:3.1.1.69-RXN	Note that this function was formerly EC:3.1.1.69.								molecular_function											owl:Class	
GO:0045109	biolink:NamedThing	intermediate filament organization	Control of the spatial distribution of intermediate filaments; includes organizing filaments into meshworks, bundles, or other structures, as by cross-linking.	tmpzr1t_l9r_go_relaxed.owl	intermediate filament organisation													biological_process											owl:Class	
GO:0018360	biolink:NamedThing	protein-heme P460 linkage via heme P460-bis-L-cysteine-L-lysine	The linkage of protein to heme P460 via heme P460-bis-L-cysteine-L-lysine.	tmpzr1t_l9r_go_relaxed.owl	protein-haem P460 linkage via haem P460-bis-L-cysteine-L-lysine				RESID:AA0271							GO:0018384		biological_process											owl:Class	
GO:0018174	biolink:NamedThing	protein-heme P460 linkage	The linkage of protein to heme P460.	tmpzr1t_l9r_go_relaxed.owl	protein-haem P460 linkage				RESID:AA0266|RESID:AA0271									biological_process											owl:Class	
GO:2000085	biolink:NamedThing	negative regulation of mesenchymal to epithelial transition involved in mesonephros morphogenesis	Any process that stops, prevents, or reduces the frequency, rate or extent of mesenchymal to epithelial transition involved in mesonephros morphogenesis.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of mesonephric mesenchyme to epithelial transition							dph	2010-09-03T06:08:21Z					biological_process											owl:Class	
GO:1902300	biolink:NamedThing	galactarate transmembrane transport	The process in which galactaric acid anion (galactarate) is transported across a lipid bilayer, from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	galactarate transport|D-galactarate transport|galactaric acid anion transport							pr	2013-07-16T07:11:45Z			GO:0042871		biological_process											owl:Class	
GO:0047760	biolink:NamedThing	butyrate-CoA ligase activity	Catalysis of the reaction: ATP + an acid + CoA = AMP + diphosphate + an acyl-CoA.	tmpzr1t_l9r_go_relaxed.owl	acyl-activating enzyme activity|fatty acyl coenzyme A synthetase activity|medium chain acyl-CoA synthetase activity|short-chain acyl-CoA synthetase activity|butanoate:CoA ligase (AMP-forming)|fatty acid thiokinase (medium chain) activity|butyryl-coenzyme A synthetase activity|butyryl-CoA synthetase activity|L-(+)-3-hydroxybutyryl CoA ligase activity|fatty acid activating enzyme				Reactome:R-HSA-8875013|EC:6.2.1.2|MetaCyc:BUTYRATE--COA-LIGASE-RXN|RHEA:24336									molecular_function											owl:Class	
GO:2000520	biolink:NamedThing	regulation of immunological synapse formation	Any process that modulates the frequency, rate or extent of immunological synapse formation.	tmpzr1t_l9r_go_relaxed.owl	regulation of formation of immunological synapse							ebc	2011-03-23T10:18:14Z					biological_process											owl:Class	
GO:0140121	biolink:NamedThing	Lewy body formation	The aggregation, arrangement and bonding together of a set of components to form a Lewy body.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/14160						pg	2017-10-25T06:59:12Z					biological_process											owl:Class	
GO:1901878	biolink:NamedThing	positive regulation of calcium ion binding	Any process that activates or increases the frequency, rate or extent of calcium ion binding.	tmpzr1t_l9r_go_relaxed.owl	activation of calcium ion storage activity|upregulation of calcium ion binding|upregulation of calcium ion storage activity|up-regulation of calcium ion binding|up regulation of calcium ion binding|up-regulation of calcium ion storage activity|up regulation of calcium ion storage activity|activation of calcium ion binding|positive regulation of calcium ion storage activity							rl	2013-02-06T12:38:26Z					biological_process											owl:Class	
GO:2000471	biolink:NamedThing	regulation of hematopoietic stem cell migration	Any process that modulates the frequency, rate or extent of hematopoietic stem cell migration.	tmpzr1t_l9r_go_relaxed.owl	regulation of hemopoietic stem cell migration							bf	2011-03-09T09:34:08Z					biological_process											owl:Class	
GO:0014855	biolink:NamedThing	striated muscle cell proliferation	The multiplication or reproduction of striated muscle cells, resulting in the expansion of a cell population. Striated muscles contain fibers that are divided by transverse bands into striations, and cardiac and skeletal muscle are types of striated muscle.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0033002	biolink:NamedThing	muscle cell proliferation	The expansion of a muscle cell population by cell division.	tmpzr1t_l9r_go_relaxed.owl	myocyte proliferation													biological_process											owl:Class	
GO:1903443	biolink:NamedThing	cellular response to lipoic acid	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipoic acid stimulus.	tmpzr1t_l9r_go_relaxed.owl								jl	2014-09-17T13:52:12Z					biological_process											owl:Class	
GO:0001567	biolink:NamedThing	cholesterol 25-hydroxylase activity	Catalysis of the reaction: AH(2) + cholesterol + O(2) = 25-hydroxycholesterol + A + H(2)O.	tmpzr1t_l9r_go_relaxed.owl	cholesterol,hydrogen-donor:oxygen oxidoreductase (25-hydroxylating) activity|cholesterol 25-monooxygenase activity				MetaCyc:1.14.99.38-RXN|RHEA:21104|EC:1.14.99.38|KEGG_REACTION:R07218									molecular_function											owl:Class	
GO:0022610	biolink:NamedThing	biological adhesion	The attachment of a cell or organism to a substrate, another cell, or other organism. Biological adhesion includes intracellular attachment between membrane regions.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0090678	biolink:NamedThing	cell dedifferentiation involved in phenotypic switching	A cell dedifferentiation process that is a part of a reversible switch of a cell from one cell type or form to another, at a frequency above the expected frequency for somatic mutations.	tmpzr1t_l9r_go_relaxed.owl								tb	2016-04-28T17:32:40Z					biological_process											owl:Class	
GO:0034193	biolink:NamedThing	L-galactonate metabolic process	The chemical reactions and pathways involving L-galactonate, the anion of L-galactonic acid.	tmpzr1t_l9r_go_relaxed.owl	L-galactonate metabolism													biological_process											owl:Class	
GO:0070318	biolink:NamedThing	positive regulation of G0 to G1 transition	A cell cycle process that activates or increases the rate or extent of the transition from the G0 quiescent state to the G1 phase.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0036056	biolink:NamedThing	filtration diaphragm	A specialized cell-cell junction found between the cells of the excretory system, which provides a barrier for filtration of blood or hemolymph.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-12-12T04:36:05Z					cellular_component											owl:Class	
GO:0044302	biolink:NamedThing	dentate gyrus mossy fiber	Distinctive, unmyelinated axons produced by granule cells.	tmpzr1t_l9r_go_relaxed.owl	dentate gyrus mossy fibre|granule cell axon				NIF_Subcellular:nlx_subcell_20090601			jl	2010-02-05T11:23:55Z					cellular_component											owl:Class	
GO:0002399	biolink:NamedThing	MHC class II protein complex assembly	The aggregation, arrangement and bonding together of a set of components to form an MHC class II protein complex.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0075109	biolink:NamedThing	modulation by symbiont of host receptor-mediated signal transduction	Any process in which the symbiont modulates the frequency, rate or extent of receptor-mediated signal transduction in the host organism. The receptor is defined as a protein on the cell membrane or within the cytoplasm or cell nucleus that binds to a specific molecule (a ligand) such as a neurotransmitter or a hormone or other substance, and initiates the cellular response to the ligand. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl						Note that this term is used to annotate gene products of the symbiont. To annotate host gene products, consider the biological process term "modulation by host of symbiont receptor-mediated signal transduction ; GO:0075078".								biological_process											owl:Class	
GO:0062232	biolink:NamedThing	prostanoid catabolic process	The chemical reactions and pathways resulting in the breakdown of prostanoids.	tmpzr1t_l9r_go_relaxed.owl								dph	2020-03-23T15:17:02Z					biological_process											owl:Class	
GO:0106375	biolink:NamedThing	deoxynucleoside triphosphate hydrolase activity	Catalysis of the reaction:  dNTP + H2O = 2'-deoxynucleoside + H+ + triphosphate.	tmpzr1t_l9r_go_relaxed.owl					RHEA:46148			hjd	2021-04-15T20:44:33Z					molecular_function											owl:Class	
GO:0039697	biolink:NamedThing	negative stranded viral RNA transcription	A viral transcription process that uses negative stranded (-) single stranded (ss) RNA as a template.	tmpzr1t_l9r_go_relaxed.owl					VZ:1096			bf	2013-10-28T14:41:41Z					biological_process											owl:Class	
GO:0140292	biolink:NamedThing	ADP-ribosylserine hydrolase activity	Catalysis of the reaction: (ADP-D-ribosyl)-L-seryl-[protein] + H2O = L-seryl-[protein] + ADP-ribose.	tmpzr1t_l9r_go_relaxed.owl								pg	2018-11-22T14:35:39Z					molecular_function											owl:Class	
GO:1905680	biolink:NamedThing	regulation of innate immunity memory response	Any process that modulates the frequency, rate or extent of innate immunity memory response.	tmpzr1t_l9r_go_relaxed.owl								tb	2016-11-11T22:25:21Z					biological_process											owl:Class	
GO:0045569	biolink:NamedThing	TRAIL binding	Binding to TRAIL (TNF-related apoptosis inducing ligand), a member of the tumor necrosis factor ligand family that rapidly induces apoptosis in a variety of transformed cell lines.	tmpzr1t_l9r_go_relaxed.owl	Apo-2L binding													molecular_function											owl:Class	
GO:0042599	biolink:NamedThing	lamellar body	A membrane-bounded organelle, specialized for the storage and secretion of various substances (surfactant phospholipids, glycoproteins and acid phosphates) which are arranged in the form of tightly packed, concentric, membrane sheets or lamellae. Has some similar properties to, but is distinct from, a lysosome.	tmpzr1t_l9r_go_relaxed.owl	keratinosome|membrane-coating granule|lamellar granule|Odland body				NIF_Subcellular:sao1379604862									cellular_component											owl:Class	
GO:0102335	biolink:NamedThing	N,N'-diacetylbacillosaminyl-diphospho-undecaprenol alpha-1,3-N-acetylgalactosaminyltransferase activity	Catalysis of the reaction: N,N'-diacetyl-alpha-D-bacillosaminyl-diphospho-tri-trans,hepta-cis-undecaprenol + UDP-N-acetyl-D-galactosamine <=> N-acetyl-D-galactosaminyl-alpha-(1->3)-N,N'-diacetyl-alpha-D-bacillosaminyl-diphospho-tri-trans,hepta-cis-undecaprenol + UDP + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-13274|EC:2.4.1.290|RHEA:34511									molecular_function											owl:Class	
GO:0006666	biolink:NamedThing	3-keto-sphinganine metabolic process	The chemical reactions and pathways involving 3-keto-sphinganine, a derivative of sphinganine with a ketone group at C3. It is an intermediate in the synthesis of sphingosine.	tmpzr1t_l9r_go_relaxed.owl	3-keto-dihydrosphingosine metabolism|3-keto-dihydrosphingosine metabolic process|3-keto-sphinganine metabolism													biological_process											owl:Class	
GO:0102605	biolink:NamedThing	cyclooctat-9-en-5,7-diol C18-monooxygenase activity	Catalysis of the reaction: cyclooctat-9-en-5,7-diol + O2 + NADPH + H+ <=> cyclooctatin + H2O + NADP.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-15430|RHEA:56824									molecular_function											owl:Class	
GO:0006842	biolink:NamedThing	tricarboxylic acid transport	The directed movement of tricarboxylic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0000822	biolink:NamedThing	inositol hexakisphosphate binding	Binding to inositol hexakisphosphate.	tmpzr1t_l9r_go_relaxed.owl	IP6 binding|InsP6 binding													molecular_function											owl:Class	
GO:1905286	biolink:NamedThing	serine-type peptidase complex	A protein complex which is capable of serine-type peptidase activity.	tmpzr1t_l9r_go_relaxed.owl	Factor VII - TF complex					An example of this is F7 in human (P08709) in PMID:18640965 (inferred from direct assay).		bhm	2016-06-21T14:20:20Z					cellular_component											owl:Class	
GO:0102379	biolink:NamedThing	steviolbioside glucosyltransferase activity (stevioside forming)	Catalysis of the reaction: steviolbioside + UDP-alpha-D-glucose = stevioside + UDP + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-13514									molecular_function											owl:Class	
GO:0072502	biolink:NamedThing	cellular trivalent inorganic anion homeostasis	Any process involved in the maintenance of an internal steady state of trivalent inorganic anions at the level of a cell.	tmpzr1t_l9r_go_relaxed.owl						Note that this term was split from 'cellular di-, tri-valent inorganic anion homeostasis ; GO:0030319' (sibling term 'cellular divalent inorganic anion homeostasis' ; GO:0072501').		mah	2010-12-16T12:53:42Z					biological_process											owl:Class	
GO:0038160	biolink:NamedThing	CXCL12-activated CXCR4 signaling pathway	A series of molecular signals initiated by the binding of the C-X-C chemokine CXCL12 to a C-X-C chemokine type 4 receptor (CXCR4) on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.	tmpzr1t_l9r_go_relaxed.owl	CXCL12-activated CXCR4 signalling pathway							bf	2012-05-14T01:33:17Z					biological_process											owl:Class	
GO:0039632	biolink:NamedThing	RNA translocase activity involved in viral RNA genome packaging	Catalysis of the reaction: ATP + H2O = ADP + phosphate, to drive movement along a single- or double-stranded RNA molecule, which contributes to the packaging of viral RNA into a nucleocapsid.	tmpzr1t_l9r_go_relaxed.owl	RNA packaging ATPase activity|viral RNA packaging activity							bf	2012-08-07T11:20:53Z					molecular_function											owl:Class	
GO:0039630	biolink:NamedThing	RNA translocase activity	Generating a movement along a single- or double-stranded RNA molecule, driven by ATP hydrolysis.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/21612				Note that some gene products that possess DNA translocase activity, such as members of the FtsK/SpoIIIE family, can be fixed in place by interactions with other components of the cell; the relative movement between the protein and DNA bound to it results in movement of the DNA within the cell, often across a membrane.		bf	2012-08-06T13:24:51Z					molecular_function											owl:Class	
GO:0048926	biolink:NamedThing	electrosensory lateral line system development	The process whose specific outcome is the progression of the electrosensory lateral line system over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0006660	biolink:NamedThing	phosphatidylserine catabolic process	The chemical reactions and pathways resulting in the breakdown of phosphatidylserines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of L-serine.	tmpzr1t_l9r_go_relaxed.owl	phosphatidylserine degradation|phosphatidylserine breakdown|phosphatidylserine catabolism													biological_process											owl:Class	
GO:0075283	biolink:NamedThing	sporulation resulting in formation of a multicellular or syncytial spore	The process whose specific outcome is the progression of a multicellular or syncytial spore via septations over time, from its initiation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl	multicellular or syncytial spore formation by sporulation													biological_process											owl:Class	
GO:1990526	biolink:NamedThing	Ste12p-Dig1p-Dig2p complex	A multiprotein complex that is involved in the transcription regulation of mating genes in the yeast S. cerevisiae.	tmpzr1t_l9r_go_relaxed.owl								rb	2014-11-05T22:49:32Z					cellular_component											owl:Class	
GO:0032170	biolink:NamedThing	pseudohyphal septin ring	A tight ring-shaped structure that forms in the division plane at the junction between the mother cell and a pseudohyphal projection; composed of septins as well as septin-associated proteins.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0048882	biolink:NamedThing	lateral line development	The process whose specific outcome is the progression of the lateral line over time, from its formation to the mature structure. The lateral line consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the head and body of all fishes and most amphibians. The lateral line develops from cranial ectodermal placodes situated behind the ear and between the eye and ear.	tmpzr1t_l9r_go_relaxed.owl	LL development													biological_process											owl:Class	
GO:0070629	biolink:NamedThing	(1->4)-alpha-glucan metabolic process	The chemical reactions and pathways involving (1->4)-alpha-glucans, compounds composed of glucose residues linked by (1->4)-alpha-D-glucosidic bonds.	tmpzr1t_l9r_go_relaxed.owl	alpha-1,4 glucan metabolic process|1,4-alpha-D-glucan metabolism|(1->4)-alpha-D-glucan metabolism|1,4-alpha-glucan metabolism|alpha-1,4 glucan metabolism							mah	2009-05-01T04:45:42Z					biological_process											owl:Class	
GO:0034590	biolink:NamedThing	L-hydroxyproline transmembrane transporter activity	Enables the transfer of L-hydroxyproline from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	4-hydroxyproline transmembrane transporter activity				Reactome:R-HSA-6784213									molecular_function											owl:Class	
GO:1990722	biolink:NamedThing	DAPK1-calmodulin complex	A serine/threonine protein kinase complex involved in cell survival, apoptosis and autophagic cell death pathways. DAPK1 is activated by the dephosphorylation of a n-terminal serine and calcium-calmodulin binding.	tmpzr1t_l9r_go_relaxed.owl	death-associated protein kinase 1 - calmodulin complex							bhm	2015-04-01T13:05:17Z					cellular_component											owl:Class	
GO:0033785	biolink:NamedThing	heptose 7-phosphate kinase activity	Catalysis of the reaction: D-alpha,beta-D-heptose-7-phosphate + ATP = D-beta-D-heptose-1,7-bisphosphate + ADP.	tmpzr1t_l9r_go_relaxed.owl	D-alpha,beta-D-heptose 7-phosphate 1-kinase activity				RHEA:27473|MetaCyc:RXN0-4341|EC:2.7.1.167									molecular_function											owl:Class	
GO:0048618	biolink:NamedThing	post-embryonic foregut morphogenesis	The process in which the anatomical structures of the foregut are generated and organized, during the post-embryonic phase.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0004933	biolink:NamedThing	mating-type a-factor pheromone receptor activity	Combining with the mating-type a-factor pheromone to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	class D G-protein coupled receptor activity|class D GPCR activity|class D G protein coupled receptor activity|class D G-protein-coupled receptor activity													molecular_function											owl:Class	
GO:0031548	biolink:NamedThing	regulation of brain-derived neurotrophic factor receptor signaling pathway	Any process that modulates the frequency, rate or extent of signaling via the brain-derived neurotrophic factor receptor signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	regulation of BDNF receptor signaling pathway|regulation of brain-derived neurotrophic factor receptor signalling pathway|regulation of BDNF receptor signalling pathway													biological_process											owl:Class	
GO:0090374	biolink:NamedThing	oligopeptide export from mitochondrion	The process in which an oligopeptide is transported out of the mitochondrial matrix. Oligopeptides are molecules that contain a small number (2 to 20) of amino-acid residues connected by peptide linkages.	tmpzr1t_l9r_go_relaxed.owl								tb	2010-08-27T04:38:18Z					biological_process											owl:Class	
GO:0050502	biolink:NamedThing	cis-zeatin O-beta-D-glucosyltransferase activity	Catalysis of the reaction: cis-zeatin + UDP-D-glucose = O-beta-D-glucosyl-cis-zeatin + H(+) + UDP.	tmpzr1t_l9r_go_relaxed.owl	cis-zeatin O-b-D-glucosyltransferase activity|UDPglucose:cis-zeatin O-beta-D-glucosyltransferase activity|UDP-glucose:cis-zeatin O-beta-D-glucosyltransferase activity				MetaCyc:RXN-4735|EC:2.4.1.215|KEGG_REACTION:R07260|RHEA:20681									molecular_function											owl:Class	
GO:0009859	biolink:NamedThing	pollen hydration	The process in which water is taken up by pollen.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0006833	biolink:NamedThing	water transport	The directed movement of water (H2O) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0033356	biolink:NamedThing	UDP-L-arabinose metabolic process	The chemical reactions and pathways involving UDP-L-arabinose, uridinediphosphoarabinose, a substance composed of arabinose in glycosidic linkage with uridine diphosphate.	tmpzr1t_l9r_go_relaxed.owl	UDP-L-arabinose metabolism													biological_process											owl:Class	
GO:0000488	biolink:NamedThing	maturation of LSU-rRNA from tetracistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 4.5S-rRNA, 5S-rRNA)	Any process involved in the maturation of a precursor Large SubUnit (LSU) ribosomal RNA (rRNA) molecule into a mature LSU-rRNA molecule from the pre-rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, Large Subunit (LSU) the 4.5S rRNA, and the 5S rRNA in that order from 5' to 3' along the primary transcript.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1990387	biolink:NamedThing	isogloboside biosynthetic process	The chemical reactions and pathways resulting in the formation of a lactosyl-ceramide derivative in which a galactose is linked to the galactose via an alpha 1,3 linkage (vs alpha 1,4 for globosides).	tmpzr1t_l9r_go_relaxed.owl								hjd	2014-05-30T17:36:51Z					biological_process											owl:Class	
GO:2001281	biolink:NamedThing	regulation of muscle cell chemotaxis toward tendon cell	Any process that modulates the frequency, rate or extent of muscle cell chemotaxis toward tendon cell.	tmpzr1t_l9r_go_relaxed.owl	regulation of muscle cell chemotaxis towards tendon cell|regulation of muscle cell attraction							bf	2011-12-15T10:39:36Z					biological_process											owl:Class	
GO:0006526	biolink:NamedThing	arginine biosynthetic process	The chemical reactions and pathways resulting in the formation of arginine, 2-amino-5-(carbamimidamido)pentanoic acid.	tmpzr1t_l9r_go_relaxed.owl	arginine biosynthesis|arginine formation|arginine anabolism|arginine synthesis				MetaCyc:ARGSYN-PWY|MetaCyc:ARGININE-SYN4-PWY|MetaCyc:ARGSYNBSUB-PWY									biological_process											owl:Class	
GO:0086022	biolink:NamedThing	SA node cell-atrial cardiac muscle cell adhesion involved in cell communication	The attachment of SA node cardiomyocyte to an atrial cardiomyocyte via adhesion molecules that results in the cells being juxtaposed so that they can communicate.	tmpzr1t_l9r_go_relaxed.owl	SA cardiomyocyte-atrial cardiomyocyte adhesion involved in cell communication|sinoatrial node cardiomyocyte-atrial cardiomyocyte adhesion involved in cell communication|SAN cardiomyocyte-atrial cardiomyocyte adhesion involved in cell communication|SA cardiac muscle cell-atrial cardiac muscle cell adhesion involved in cell communication|sinus node cardiomyocyte-atrial cardiomyocyte adhesion involved in cell communication							tb	2011-11-10T09:26:52Z					biological_process											owl:Class	
GO:0070213	biolink:NamedThing	protein auto-ADP-ribosylation	The ADP-ribosylation by a protein of one or more of its own amino acid residues, or residues on an identical protein.	tmpzr1t_l9r_go_relaxed.owl	protein amino acid auto-ADP-ribosylation													biological_process											owl:Class	
GO:0006641	biolink:NamedThing	triglyceride metabolic process	The chemical reactions and pathways involving triglyceride, any triester of glycerol. The three fatty acid residues may all be the same or differ in any permutation. Triglycerides are important components of plant oils, animal fats and animal plasma lipoproteins.	tmpzr1t_l9r_go_relaxed.owl	triacylglycerol metabolism|triglyceride metabolism|triacylglycerol metabolic process													biological_process											owl:Class	
GO:0045584	biolink:NamedThing	negative regulation of cytotoxic T cell differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of cytotoxic T cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of cytotoxic T cell development|negative regulation of cytotoxic T lymphocyte differentiation|negative regulation of cytotoxic T-cell differentiation|down regulation of cytotoxic T cell differentiation|downregulation of cytotoxic T cell differentiation|negative regulation of cytotoxic T-lymphocyte differentiation|down-regulation of cytotoxic T cell differentiation|inhibition of cytotoxic T cell differentiation					Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.								biological_process											owl:Class	
GO:0005260	biolink:NamedThing	intracellularly ATP-gated chloride channel activity	Enables passage of a chloride ion through a transmembrane channel that opens when ATP is bound by the channel complex or one of its constituent parts on the intracellular side of the plasma membrane.	tmpzr1t_l9r_go_relaxed.owl	ATP-binding and phosphorylation-dependent chloride channel activity|channel-conductance-controlling ATPase activity|cystic fibrosis transmembrane conductance regulator|ATP phosphohydrolase (channel-conductance-controlling)|cystic-fibrosis membrane-conductance-regulating protein activity	https://github.com/geneontology/go-ontology/issues/14402			EC:5.6.1.6|MetaCyc:3.6.3.49-RXN							GO:0005224		molecular_function											owl:Class	
GO:0070280	biolink:NamedThing	pyridoxal binding	Binding to pyridoxal, 3-hydroxy-5-(hydroxymethyl)-2-methylpyridine-4-carbaldehyde, a form of vitamin B6.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1902466	biolink:NamedThing	positive regulation of histone H3-K27 trimethylation	Any process that activates or increases the frequency, rate or extent of histone H3-K27 trimethylation.	tmpzr1t_l9r_go_relaxed.owl	upregulation of histone H3-K27 trimethylation|up-regulation of histone H3-K27 trimethylation|up regulation of histone H3-K27 trimethylation|activation of histone H3-K27 trimethylation							krc	2013-10-22T14:59:19Z					biological_process											owl:Class	
GO:0019864	biolink:NamedThing	IgG binding	Binding to an immunoglobulin of an IgG isotype.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0047213	biolink:NamedThing	anthocyanidin 3-O-glucosyltransferase activity	Catalysis of the reaction: anthocyanidin + UDP-D-glucose = anthocyanidin-3-O-D-glucoside + UDP.	tmpzr1t_l9r_go_relaxed.owl	3-GT activity|UDP-glucose:anthocyanidin/flavonol 3-O-glucosyltransferase activity|uridine diphosphoglucose-anthocyanidin 3-O-glucosyltransferase activity|UDP-glucose:anthocyanidin 3-O-D-glucosyltransferase activity|UDP-glucose:cyanidin-3-O-glucosyltransferase activity|UDP-D-glucose:anthocyanidin 3-O-beta-D-glucosyltransferase activity				EC:2.4.1.115|RHEA:20093|MetaCyc:2.4.1.115-RXN									molecular_function											owl:Class	
GO:0097131	biolink:NamedThing	cyclin D1-CDK6 complex	A protein complex consisting of cyclin D1 and cyclin-dependent kinase 6 (CDK6). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner.	tmpzr1t_l9r_go_relaxed.owl								pr	2011-08-01T01:55:26Z					cellular_component											owl:Class	
GO:0080032	biolink:NamedThing	methyl jasmonate esterase activity	Catalysis of the reaction: a methyl jasmonate + H2O = a jasmonic acid + methanol.	tmpzr1t_l9r_go_relaxed.owl	methyl JA esterase activity|jasmonic acid methyl ester esterase activity|MEJA esterase activity				MetaCyc:RXN-10767									molecular_function											owl:Class	
GO:0004817	biolink:NamedThing	cysteine-tRNA ligase activity	Catalysis of the reaction: ATP + L-cysteine + tRNA(Cys) = AMP + diphosphate + L-cysteinyl-tRNA(Cys).	tmpzr1t_l9r_go_relaxed.owl	cysteinyl-transferRNA synthetase activity|cysteinyl-transfer ribonucleate synthetase activity|cysteine translase activity|L-cysteine:tRNACys ligase (AMP-forming)|cysteinyl-tRNA synthetase activity				Reactome:R-HSA-380158|EC:6.1.1.16|MetaCyc:CYSTEINE--TRNA-LIGASE-RXN|Reactome:R-HSA-379887|RHEA:17773									molecular_function											owl:Class	
GO:0097360	biolink:NamedThing	chorionic trophoblast cell proliferation	The multiplication or reproduction of chorionic trophoblast cells, resulting in the expansion of their population.	tmpzr1t_l9r_go_relaxed.owl								pr	2012-07-19T10:17:37Z					biological_process											owl:Class	
GO:0019146	biolink:NamedThing	arabinose-5-phosphate isomerase activity	Catalysis of the reaction: D-arabinose 5-phosphate = D-ribulose 5-phosphate + 2 H(+).	tmpzr1t_l9r_go_relaxed.owl	arabinose phosphate isomerase activity|D-arabinose-5-phosphate aldose-ketose-isomerase activity|phosphoarabinoisomerase activity|D-arabinose-5-phosphate ketol-isomerase activity				EC:5.3.1.13|RHEA:23104|KEGG_REACTION:R01530|MetaCyc:DARAB5PISOM-RXN									molecular_function											owl:Class	
GO:1990181	biolink:NamedThing	acetyl-CoA biosynthetic process from pantothenate	The chemical reactions and pathways resulting in the formation of acetyl-CoA from pantothenate via phosphopantothenate and CoA.	tmpzr1t_l9r_go_relaxed.owl	acetyl-CoA synthesis from pantothenate|acetyl-CoA anabolism from pantothenate|acetyl-CoA formation from pantothenate							mah	2013-08-30T16:20:44Z					biological_process											owl:Class	
GO:0018875	biolink:NamedThing	anaerobic benzoate metabolic process	The chemical reactions and pathways involving benzoate, the anion of benzoic acid (benzenecarboxylic acid) that occur in the absence of oxygen.	tmpzr1t_l9r_go_relaxed.owl	anaerobic benzoate metabolism				UM-BBD_pathwayID:benz|MetaCyc:CENTBENZCOA-PWY									biological_process											owl:Class	
GO:0006642	biolink:NamedThing	triglyceride mobilization	The release of triglycerides, any triester of glycerol, from storage within cells or tissues, making them available for metabolism.	tmpzr1t_l9r_go_relaxed.owl	triacylglycerol mobilization													biological_process											owl:Class	
GO:0090385	biolink:NamedThing	phagosome-lysosome fusion	The creation of a phagolysosome from a phagosome and a lysosome.	tmpzr1t_l9r_go_relaxed.owl								tb	2010-10-27T10:24:28Z					biological_process											owl:Class	
GO:1904838	biolink:NamedThing	regulation of male germ-line stem cell asymmetric division	Any process that modulates the frequency, rate or extent of male germ-line stem cell asymmetric division.	tmpzr1t_l9r_go_relaxed.owl	regulation of male germ-line stem cell renewal							sl	2015-12-05T00:28:31Z					biological_process											owl:Class	
GO:0071098	biolink:NamedThing	alpha6-beta4 integrin-Fyn complex	A protein complex that consists of an alpha6-beta4 integrin complex bound to the Src family tyrosine kinase Fyn.	tmpzr1t_l9r_go_relaxed.owl	ITGA6-ITGB4-FYN complex							mah	2009-11-06T04:52:10Z					cellular_component											owl:Class	
GO:0005183	biolink:NamedThing	gonadotropin hormone-releasing hormone activity	The action characteristic of gonadotropin hormone-releasing hormone (GnRH), any of a family of decapeptide amide hormones that are released by the hypothalamus in response to neural and/or chemical stimuli. In at least mammals, upon receptor binding, GnRH causes the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) by the anterior pituitary.	tmpzr1t_l9r_go_relaxed.owl	gonadotrophin hormone-releasing hormone activity|luteinizing hormone-releasing factor activity|luteinizing hormone/follicle-stimulating hormone releasing factor activity|LH/FSH-RF|GnRH activity|LHRH activity|luteinizing hormone-releasing hormone activity													molecular_function											owl:Class	
GO:0039519	biolink:NamedThing	modulation by virus of host autophagy	Any process in which a virus effect a change in the frequency, rate or extent of autophagy in the host.	tmpzr1t_l9r_go_relaxed.owl	regulation by virus of host autophagy							bf	2011-06-22T04:19:19Z					biological_process											owl:Class	
GO:0048798	biolink:NamedThing	swim bladder inflation	The expansion of the swim bladder by trapped gases. The swim bladder is used by some fishes to maintain buoyancy and may function in addition as a sound producing organ, a sound receptor, and a respiratory organ.	tmpzr1t_l9r_go_relaxed.owl	gas bladder inflation													biological_process											owl:Class	
GO:0001940	biolink:NamedThing	male pronucleus	The pronucleus originating from the spermatozoa that was involved in fertilization.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0097583	biolink:NamedThing	dolichyl-phosphate-mannose-protein mannosyltransferase Pmt1p-Pmt3p dimer complex	A protein dimer complex that possesses dolichyl-phosphate-mannose-protein mannosyltransferase activity and, in S. cerevisiae, is composed of Pmt1p-Pmt3p.	tmpzr1t_l9r_go_relaxed.owl	Pmt1p-Pmt3p complex							pr	2014-03-02T18:16:29Z					cellular_component											owl:Class	
GO:2000611	biolink:NamedThing	positive regulation of thyroid hormone generation	Any process that activates or increases the frequency, rate or extent of thyroid hormone generation.	tmpzr1t_l9r_go_relaxed.owl								yaf	2011-04-18T10:12:22Z					biological_process											owl:Class	
GO:0051110	biolink:NamedThing	peptidyl-histidine uridylylation, to form peptidyl-1'-(phospho-5'-uridine)-L-histidine	The uridylylation of peptidyl-histidine to form peptidyl-1'-(phospho-5'-uridine)-L-histidine (otherwise known as tau-UMP-histidine, tele-UMP-histidine).	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0372									biological_process											owl:Class	
GO:0016669	biolink:NamedThing	oxidoreductase activity, acting on a sulfur group of donors, cytochrome as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which a sulfur-containing group acts as a hydrogen or electron donor and reduces a cytochrome.	tmpzr1t_l9r_go_relaxed.owl	oxidoreductase activity, acting on sulphur group of donors, cytochrome as acceptor				EC:1.8.2.-									molecular_function											owl:Class	
GO:2000157	biolink:NamedThing	negative regulation of ubiquitin-specific protease activity	Any process that stops, prevents, or reduces the frequency, rate or extent of ubiquitin-specific protease (deubiquitinase) activity.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of UBP|negative regulation of UCH2|negative regulation of ubiquitin hydrolase activity|negative regulation of deubiquitinase activity							tb	2010-10-04T10:42:27Z					biological_process											owl:Class	
GO:0002799	biolink:NamedThing	positive regulation of antibacterial peptide secretion	Any process that activates or increases the frequency, rate, or extent of antibacterial peptide secretion.	tmpzr1t_l9r_go_relaxed.owl	stimulation of antibacterial peptide secretion|up-regulation of antibacterial peptide secretion|activation of antibacterial peptide secretion|upregulation of antibacterial peptide secretion|up regulation of antibacterial peptide secretion													biological_process											owl:Class	
GO:0015911	biolink:NamedThing	long-chain fatty acid import across plasma membrane	The directed movement of long-chain fatty acids from outside of a cell, across the plasma membrane and into the cytosol. A long-chain fatty acid is a fatty acid with a chain length between C13 and C22.	tmpzr1t_l9r_go_relaxed.owl	plasma membrane long-chain fatty acid transport													biological_process											owl:Class	
GO:1902001	biolink:NamedThing	fatty acid transmembrane transport	The process in which a fatty acid is transported across a membrane.	tmpzr1t_l9r_go_relaxed.owl								pr	2013-03-21T09:57:00Z					biological_process											owl:Class	
GO:0019596	biolink:NamedThing	mandelate catabolic process	The chemical reactions and pathways resulting in the breakdown of mandelate, the anion of mandelic acid. Mandelic acid (alpha-hydroxybenzeneacetic acid) is an 8-carbon alpha-hydroxy acid (AHA) that is used in organic chemistry and as a urinary antiseptic.	tmpzr1t_l9r_go_relaxed.owl	mandelate breakdown|mandelate degradation|mandelate catabolism													biological_process											owl:Class	
GO:0010643	biolink:NamedThing	cell communication by chemical coupling	The process that mediates signaling interactions between one cell and another cell by the transfer of small, water-soluble molecules or metabolites between their adjacent cytoplasms via intercellular protein channels.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0005328	biolink:NamedThing	neurotransmitter:sodium symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: neurotransmitter(out) + Na+(out) = neurotransmitter(in) + Na+(in).	tmpzr1t_l9r_go_relaxed.owl	sodium/neurotransmitter symporter activity													molecular_function											owl:Class	
GO:0019424	biolink:NamedThing	sulfide oxidation, using siroheme sulfite reductase	A sulfide oxidation process that proceeds via the reaction catalyzed by siroheme sulfite reductase.	tmpzr1t_l9r_go_relaxed.owl	sulphur oxidation, using siroheme sulphite reductase|sulphide oxidation, using siroheme sulphite reductase|sulfur oxidation, using siroheme sulfite reductase|sulfide oxidation, using sirohaem sulfite reductase|sulfur oxidation, using sirohaem sulfite reductase				MetaCyc:P223-PWY							GO:0019425		biological_process											owl:Class	
GO:0042023	biolink:NamedThing	DNA endoreduplication	Regulated re-replication of DNA within a single cell cycle, resulting in an increased cell ploidy. An example of this process occurs in the synthesis of Drosophila salivary gland cell polytene chromosomes.	tmpzr1t_l9r_go_relaxed.owl	DNA endoreplication|DNA re-duplication					Note that this term is only to be used in situations were this process occurs normally. Not to be used to describe mutant or diseased states.								biological_process											owl:Class	
GO:0046041	biolink:NamedThing	ITP metabolic process	The chemical reactions and pathways involving ITP, inosine triphosphate.	tmpzr1t_l9r_go_relaxed.owl	ITP metabolism													biological_process											owl:Class	
GO:1901504	biolink:NamedThing	triazole transport	The directed movement of a triazole into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl								pr	2012-10-17T09:47:46Z					biological_process											owl:Class	
GO:0015324	biolink:NamedThing	peptide-acetyl-CoA secondary active transmembrane transporter activity	Enables the transfer of peptide-acetyl-CoA from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters.	tmpzr1t_l9r_go_relaxed.owl	peptide-acetyl-CoA transporter activity													molecular_function											owl:Class	
GO:0071632	biolink:NamedThing	optomotor response	Eye, head or whole body movements that help to compensate movements of the environment in order to stabilize its image on the retina. In the case of whole body movements, these motor actions may also stabilize a locomotor course in response to some disturbance. Examples include: the optokinetic reflex, which allows human eyes to follow objects in motion while the head remains stationary reflex; the optomotor responses of flying insects and swimming fish.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Optomotor_response			mah	2010-02-11T04:06:41Z					biological_process											owl:Class	
GO:0004712	biolink:NamedThing	protein serine/threonine/tyrosine kinase activity	Catalysis of the reactions: ATP + a protein serine = ADP + protein serine phosphate; ATP + a protein threonine = ADP + protein threonine phosphate; and ATP + a protein tyrosine = ADP + protein tyrosine phosphate.	tmpzr1t_l9r_go_relaxed.owl	dual-specificity protein kinase|protein threonine/tyrosine kinase activity|dual-specificity kinase activity				Reactome:R-HSA-6802941|Reactome:R-HSA-6802916|Reactome:R-HSA-6802910|Reactome:R-HSA-9656212|EC:2.7.12.1|Reactome:R-HSA-6802927|Reactome:R-HSA-5674373|Reactome:R-HSA-6802922|Reactome:R-HSA-5672969|Reactome:R-HSA-6802921|Reactome:R-HSA-6802918|Reactome:R-HSA-6802924									molecular_function											owl:Class	
GO:1904817	biolink:NamedThing	serous membrane development	The process whose specific outcome is the progression of a serous membrane over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl	tunica serosa development|wall of serous sac development|serosa development							dph	2015-11-17T19:00:01Z					biological_process											owl:Class	
GO:0009240	biolink:NamedThing	isopentenyl diphosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of isopentenyl diphosphate, an isomer of dimethylallyl diphosphate and the key precursor of all isoprenoids.	tmpzr1t_l9r_go_relaxed.owl	isopentenyl diphosphate synthesis|isopentenyl diphosphate biosynthesis|isopentenyl diphosphate formation|IPP biosynthetic process|isopentenyl diphosphate anabolism|isopentenyl pyrophosphate biosynthesis|isopentenyl pyrophosphate biosynthetic process|IPP biosynthesis													biological_process											owl:Class	
GO:0043548	biolink:NamedThing	phosphatidylinositol 3-kinase binding	Binding to a phosphatidylinositol 3-kinase, any enzyme that catalyzes the addition of a phosphate group to an inositol lipid at the 3' position of the inositol ring.	tmpzr1t_l9r_go_relaxed.owl	phosphoinositide 3-kinase binding|PI3K binding													molecular_function											owl:Class	
GO:0098685	biolink:NamedThing	Schaffer collateral - CA1 synapse	A synapse between the Schaffer collateral axon of a CA3 pyramidal cell and a CA1 pyramidal cell.	tmpzr1t_l9r_go_relaxed.owl								dos	2017-02-05T16:29:43Z					cellular_component											owl:Class	
GO:1901953	biolink:NamedThing	positive regulation of anterograde dense core granule transport	Any process that activates or increases the frequency, rate or extent of anterograde dense core granule transport.	tmpzr1t_l9r_go_relaxed.owl	activation of anterograde dense core granule transport|up regulation of anterograde dense core granule transport|up-regulation of anterograde dense core granule transport|upregulation of anterograde dense core granule transport							pr	2013-02-19T13:36:35Z					biological_process											owl:Class	
GO:2000002	biolink:NamedThing	negative regulation of DNA damage checkpoint	Any process that stops, prevents, or reduces the frequency, rate or extent of a DNA damage checkpoint.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of DNA damage response, signal transduction resulting in cell cycle arrest							jl	2010-07-15T03:25:06Z					biological_process											owl:Class	
GO:0120084	biolink:NamedThing	endothelial tip cell filopodium assembly	The assembly of a filopodium, a thin, stiff protrusion extended by the endothelial tip cell of a vascular sprout.	tmpzr1t_l9r_go_relaxed.owl								krc	2017-07-07T18:05:10Z					biological_process											owl:Class	
GO:1990651	biolink:NamedThing	inositol-1,2,4,5,6-pentakisphosphate 5-phosphatase activity	Catalysis of the reaction: 1D-myo-inositol 1,2,4,5,6-pentakisphosphate + H2O = 1D-myo-inositol 1,2,4,6-tetrakisphosphate + phosphate.	tmpzr1t_l9r_go_relaxed.owl								al	2015-02-23T11:17:19Z					molecular_function											owl:Class	
GO:0051256	biolink:NamedThing	mitotic spindle midzone assembly	The cell cycle process in which the aggregation, arrangement and bonding together of a set of components forms the spindle midzone.	tmpzr1t_l9r_go_relaxed.owl	spindle midzone biogenesis involved in mitosis|mitotic spindle midzone biogenesis|mitotic spindle midzone formation|mitotic spindle midzone biosynthesis|spindle midzone formation involved in mitosis|spindle midzone assembly involved in mitosis													biological_process											owl:Class	
GO:0007221	biolink:NamedThing	positive regulation of transcription of Notch receptor target	The activation of transcription of specific genes as a result of Notch signaling, mediated by the Notch intracellular domain.	tmpzr1t_l9r_go_relaxed.owl	Notch receptor target transcription factor activation|N receptor target transcription factor activation													biological_process											owl:Class	
GO:0046964	biolink:NamedThing	3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity	Enables the transfer of 3'-phosphoadenosine 5'-phosphosulfate, a naturally occurring mixed anhydride synthesized from adenosine 5'-phosphosulfate, from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	3'-phosphoadenosine 5'-phosphosulphate transporter activity|PAPS transporter activity|adenosine 3'-phosphate 5'-phosphosulfate transmembrane transporter activity				Reactome:R-HSA-741449									molecular_function											owl:Class	
GO:0019604	biolink:NamedThing	toluene oxidation to catechol	The formation from toluene of catechol, dihydroxybenzene, by successive oxidations followed by loss of carbon dioxide (CO2).	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_pathwayID:tol|MetaCyc:TOLUENE-DEG-CATECHOL-PWY									biological_process											owl:Class	
GO:0043493	biolink:NamedThing	viral terminase complex	A complex of a large and small subunit which catalyze the packaging of DNA into viral heads. Note that not all viral terminases have this structure, some exist as single polypeptides.	tmpzr1t_l9r_go_relaxed.owl	phage terminase complex|virus terminase complex													cellular_component											owl:Class	
GO:0036356	biolink:NamedThing	cyclic 2,3-diphosphoglycerate synthetase activity	Catalysis of the reaction: 2,3-diphosphoglycerate (DPG) + ATP = cyclic 2,3-diphosphoglycerate (cDPG) + ADP + phosphate.	tmpzr1t_l9r_go_relaxed.owl	cDPGS activity|CPGS activity					This reaction is the intramolecular cyclization of 2,3-diphosphoglycerate to cyclic 2,3-diphosphoglycerate and is the second step in the biosynthesis of cyclic 2,3-diphosphoglycerate (cDPG).		bf	2012-09-19T14:59:19Z					molecular_function											owl:Class	
GO:0034209	biolink:NamedThing	sterol acetylation	The addition of an acetyl group to a sterol molecule. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0047331	biolink:NamedThing	diphosphate-glycerol phosphotransferase activity	Catalysis of the reaction: glycerol + diphosphate = glycerol 1-phosphate + H(+) + phosphate.	tmpzr1t_l9r_go_relaxed.owl	PPi-glycerol phosphotransferase activity|diphosphate:glycerol 1-phosphotransferase activity|pyrophosphate--glycerol phosphotransferase activity				RHEA:13689|EC:2.7.1.79|KEGG_REACTION:R01044|MetaCyc:2.7.1.79-RXN									molecular_function											owl:Class	
GO:2000270	biolink:NamedThing	negative regulation of fibroblast apoptotic process	Any process that stops, prevents or reduces the frequency, rate or extent of fibroblast apoptotic process.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of fibroblast apoptosis							jl	2010-11-23T01:07:27Z					biological_process											owl:Class	
GO:0061849	biolink:NamedThing	telomeric G-quadruplex DNA binding	Binding to telomeric G-quadruplex DNA structures, in which groups of four guanines adopt a flat, cyclic Hoogsteen hydrogen-bonding arrangement known as a guanine tetrad. The stacking of guanine tetrads results in G-quadruplex DNA structures in telomeres.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0039548	biolink:NamedThing	suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity	Any process in which a virus stops, prevents, or reduces a viral-induced cytoplasmic pattern recognition receptor signaling pathway in a host organism by reducing the activity of host IRF3 (interferon regulatory factor-3). IRF3 is a transcription factor in the RIG-I/MDA-5 signaling pathway. Viral infection triggers phosphorylation of cytoplasmic IRF3, which allows IRF3 to form a homodimer, migrate to the nucleus, and activate transcription of IFN-alpha and IFN-beta genes.	tmpzr1t_l9r_go_relaxed.owl	suppression by virus of host interferon regulatory factor 3|suppression by virus of host IRF3 activity|inhibition of host IRF3 by virus|inhibition of IRF3-dependent antiviral response	https://github.com/geneontology/go-ontology/issues/21985				This term is for annotation of viral proteins that counteract the host anti-viral innate immune response.		bf	2012-01-19T04:04:26Z					biological_process											owl:Class	
GO:0052084	biolink:NamedThing	modulation by symbiont of host ethylene-mediated defense response	Any process in which a symbiont modulates the frequency, rate or extent of the ethylene-mediated defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	modulation by symbiont of defense-related host ethylene-mediated signal transduction pathway|modulation by organism of defense-related ethylene-mediated signal transduction pathway in other organism involved in symbiotic interaction|modulation by organism of ethylene-mediated defense response of other organism involved in symbiotic interaction											GO:0052077|GO:0052279|GO:0052441		biological_process											owl:Class	
GO:0021574	biolink:NamedThing	rhombomere 8 development	The process whose specific outcome is the progression of rhombomere 8 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0090001	biolink:NamedThing	replication fork arrest at tRNA locus	A process that impedes the progress of the DNA replication fork at natural replication fork pausing sites within the eukaryotic tRNA transcription unit.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-06-24T11:36:15Z					biological_process											owl:Class	
GO:0043111	biolink:NamedThing	replication fork arrest	Any process that stops, prevents, or reduces the frequency, rate or extent of DNA replication by impeding the progress of the DNA replication fork. Replication fork arrest is one of the 'quality control' processes ensuring that DNA-dependent DNA replication occurs correctly. DNA replication fork arrest during DNA-dependent DNA replication is not known to occur outside of cases where a replication error needs to be prevented or corrected.	tmpzr1t_l9r_go_relaxed.owl	replication fork stalling|negative regulation of DNA replication at replication fork barrier|replication fork blocking					See also the biological process term 'site-specific replication termination ; GO:0071170' and its children.								biological_process											owl:Class	
GO:0050809	biolink:NamedThing	diazepam binding	Binding to diazepam, one of the most widely used benzodiazepine drugs. It is used as an anti-anxiety-hypnotic agent and has the proprietary name Valium.	tmpzr1t_l9r_go_relaxed.owl	diazepam binding inhibitor activity|Valium binding													molecular_function											owl:Class	
GO:0010423	biolink:NamedThing	negative regulation of brassinosteroid biosynthetic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of brassinosteroids.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0043155	biolink:NamedThing	negative regulation of photosynthesis, light reaction	Any process that stops, prevents, or reduces the frequency, rate or extent of the light-dependent reaction of photosynthesis.	tmpzr1t_l9r_go_relaxed.owl	downregulation of photosynthesis, light reaction|inhibition of photosynthesis, light reaction|down-regulation of photosynthesis, light reaction|down regulation of photosynthesis, light reaction													biological_process											owl:Class	
GO:0061248	biolink:NamedThing	mesonephric glomerulus vasculature morphogenesis	The process in which the anatomical structures of the mesonephric glomerulus vasculature are generated and organized. The mesonephric glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the mesonephric glomerulus.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-08-30T01:11:34Z					biological_process											owl:Class	
GO:0033576	biolink:NamedThing	protein glycosylation in cytosol	The addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid in the cytosol.	tmpzr1t_l9r_go_relaxed.owl	protein amino acid glycosylation in cytosol													biological_process											owl:Class	
GO:0009825	biolink:NamedThing	multidimensional cell growth	The process in which a cell irreversibly increases in size in two or three [spatial] dimensions or along two or three axes.	tmpzr1t_l9r_go_relaxed.owl	cell growth in two dimensions|cell growth in three dimensions													biological_process											owl:Class	
GO:0004366	biolink:NamedThing	glycerol-3-phosphate O-acyltransferase activity	Catalysis of the reaction: acyl-CoA + sn-glycerol 3-phosphate = CoA + 1-acyl-sn-glycerol 3-phosphate.	tmpzr1t_l9r_go_relaxed.owl	acyl-CoA:sn-glycerol-3-phosphate 1-O-acyltransferase activity|sn-glycerol-3-phosphate acyltransferase activity|glycerol 3-phosphate acyltransferase activity|3-glycerophosphate acyltransferase activity|alpha-glycerophosphate acyltransferase activity|glycerol phosphate transacylase activity|ACP:sn-glycerol-3-phosphate acyltransferase activity|glycerophosphate acyltransferase activity|sn-glycerol 3-phosphate acyltransferase activity|glycerophosphate transacylase activity|glycerol phosphate acyltransferase activity				Reactome:R-HSA-549112|Reactome:R-HSA-1482695|EC:2.3.1.15|Reactome:R-HSA-75886|MetaCyc:RXN-1381|RHEA:15325									molecular_function											owl:Class	
GO:0052598	biolink:NamedThing	histamine oxidase activity	Catalysis of the reaction: histamine + H2O + O2 = imidazole-4-acetaldehyde + NH3 + hydrogen peroxide + H+.	tmpzr1t_l9r_go_relaxed.owl	histamine:oxygen oxidoreductase (deaminating) activity|1H-Imidazole-4-ethanamine:oxygen oxidoreductase (deaminating) activity|1H-Imidazole-4-ethanamine oxidase activity				RHEA:25625|KEGG_REACTION:R02150|EC:1.4.3.22|MetaCyc:RXN-9600|Reactome:R-HSA-5696131									molecular_function											owl:Class	
GO:0050587	biolink:NamedThing	chlorite O2-lyase activity	Catalysis of the reaction: chloride + O(2) = chlorite.	tmpzr1t_l9r_go_relaxed.owl	chloride:oxygen oxidoreductase activity|chlorite dismutase activity				RHEA:21404|UM-BBD_reactionID:r0982|KEGG_REACTION:R05721|MetaCyc:1.13.11.49-RXN|EC:1.13.11.49							GO:0030065		molecular_function											owl:Class	
GO:0045140	biolink:NamedThing	inositol phosphoceramide synthase activity	Catalysis of the reaction: phytoceramide + inositol phosphate = inositol phosphoceramide + diacylglycerol.	tmpzr1t_l9r_go_relaxed.owl	IPC synthase activity				MetaCyc:RXN3O-581|EC:2.7.1.227									molecular_function											owl:Class	
GO:0018241	biolink:NamedThing	protein O-linked glycosylation via hydroxylysine	The glycosylation of protein via the O5 atom of peptidyl-hydroxylysine, forming O5-glycosyl-L-hydroxylysine; the most common form is galactosyl hydroxylysine.	tmpzr1t_l9r_go_relaxed.owl	protein amino acid O-linked glycosylation via hydroxylysine				RESID:AA0153									biological_process											owl:Class	
GO:0016330	biolink:NamedThing	second mitotic wave involved in compound eye morphogenesis	A discrete cell cycle in the third instar eye imaginal disc after progression of the morphogenetic furrow that contributes to compound eye morphogenesis. It is essential for generation of a sufficient pool of uncommitted cells to develop complete ommatidia.	tmpzr1t_l9r_go_relaxed.owl	second mitotic wave during compound eye morphogenesis													biological_process											owl:Class	
GO:0030669	biolink:NamedThing	clathrin-coated endocytic vesicle membrane	The lipid bilayer surrounding a clathrin-coated endocytic vesicle.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:1905414	biolink:NamedThing	negative regulation of dense core granule exocytosis	Any process that stops, prevents or reduces the frequency, rate or extent of dense core granule exocytosis.	tmpzr1t_l9r_go_relaxed.owl	downregulation of dense core vesicle exocytosis|down regulation of dense core granule exocytosis|downregulation of dense core granule exocytosis|down-regulation of dense core granule exocytosis|down-regulation of dense core vesicle exocytosis|inhibition of dense core vesicle exocytosis|negative regulation of dense core vesicle exocytosis|down regulation of dense core vesicle exocytosis|inhibition of dense core granule exocytosis							bf	2016-08-31T08:02:28Z					biological_process											owl:Class	
GO:0030187	biolink:NamedThing	melatonin biosynthetic process	The chemical reactions and pathways resulting in the formation of melatonin (N-acetyl-5-methoxytryptamine).	tmpzr1t_l9r_go_relaxed.owl	melatonin formation|melatonin synthesis|melatonin biosynthesis|melatonin anabolism													biological_process											owl:Class	
GO:1904390	biolink:NamedThing	cone retinal bipolar cell differentiation	The process in which a relatively unspecialized cell acquires the specialized features of a cone retinal bipolar cell.	tmpzr1t_l9r_go_relaxed.owl	cone bipolar cell differentiation|retinal cone bipolar cell differentiation							sl	2015-06-23T19:01:16Z					biological_process											owl:Class	
GO:0018465	biolink:NamedThing	vanillyl-alcohol oxidase activity	Catalysis of the reaction: O(2) + vanillyl alcohol = H(2)O(2) + vanillin.	tmpzr1t_l9r_go_relaxed.owl	4-hydroxy-2-methoxybenzyl alcohol oxidase activity|vanillyl alcohol:oxygen oxidoreductase activity				UM-BBD_reactionID:r0651|KEGG_REACTION:R02877|EC:1.1.3.38|RHEA:10036|MetaCyc:1.1.3.38-RXN									molecular_function											owl:Class	
GO:0042245	biolink:NamedThing	RNA repair	Any process that results in the repair of damaged RNA.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1900814	biolink:NamedThing	monodictyphenone catabolic process	The chemical reactions and pathways resulting in the breakdown of monodictyphenone.	tmpzr1t_l9r_go_relaxed.owl	monodictyphenone catabolism|monodictyphenone degradation|monodictyphenone breakdown							di	2012-06-04T10:11:27Z					biological_process											owl:Class	
GO:0045251	biolink:NamedThing	electron transfer flavoprotein complex	A protein complex facilitating the electron transfer from an acyl-CoA molecule to ubiquinone via its flavin adenine dinucleotide (FAD) cofactor. Usually contains an alpha and a beta subunit and the structural cofactor adenosine monophosphate (AMP). Part of a system that oxidizes an acyl-CoA molecule and reduces ubiquinone and other acceptors in the electron transport system.	tmpzr1t_l9r_go_relaxed.owl	ETF complex													cellular_component											owl:Class	
GO:0044856	biolink:NamedThing	plasma membrane raft localization	Any process in which plasma membrane rafts are transported to, or maintained in, a specific location.	tmpzr1t_l9r_go_relaxed.owl								jl	2014-07-23T16:12:22Z					biological_process											owl:Class	
GO:1902729	biolink:NamedThing	negative regulation of proteoglycan biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteoglycans, any glycoprotein in which the carbohydrate units are glycosaminoglycans.	tmpzr1t_l9r_go_relaxed.owl	down regulation of proteoglycan biosynthetic process|negative regulation of proteoglycan synthesis|down regulation of proteoglycan biosynthesis|inhibition of proteoglycan biosynthetic process|down-regulation of proteoglycan biosynthesis|downregulation of proteoglycan anabolism|down-regulation of proteoglycan anabolism|down regulation of proteoglycan formation|down regulation of proteoglycan synthesis|down-regulation of proteoglycan formation|downregulation of proteoglycan biosynthesis|downregulation of proteoglycan formation|downregulation of proteoglycan synthesis|negative regulation of proteoglycan anabolism|down-regulation of proteoglycan synthesis|down-regulation of proteoglycan biosynthetic process|inhibition of proteoglycan biosynthesis|negative regulation of proteoglycan biosynthesis|inhibition of proteoglycan synthesis|downregulation of proteoglycan biosynthetic process|inhibition of proteoglycan anabolism|inhibition of proteoglycan formation|down regulation of proteoglycan anabolism|negative regulation of proteoglycan formation							mr	2014-02-24T16:10:43Z					biological_process											owl:Class	
GO:0047825	biolink:NamedThing	D-lactate-2-sulfatase activity	Catalysis of the reaction: (R)-2-O-sulfolactate + H(2)O = (R)-lactate + H(+) + sulfate.	tmpzr1t_l9r_go_relaxed.owl	(S)-2-O-sulfolactate 2-sulfohydrolase activity|D-lactate-2-sulphatase activity				RHEA:20337|KEGG_REACTION:R01448|EC:3.1.6.17|MetaCyc:D-LACTATE-2-SULFATASE-RXN									molecular_function											owl:Class	
GO:0102876	biolink:NamedThing	psoralen synthase activity	Catalysis of the reaction: (+)-marmesin + NADPH + H+ + O2 <=> psoralen + NADP + acetone + 2 H2O.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-8386|RHEA:19281|EC:1.14.14.141									molecular_function											owl:Class	
GO:1903770	biolink:NamedThing	negative regulation of beta-galactosidase activity	Any process that stops, prevents or reduces the frequency, rate or extent of beta-galactosidase activity.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of beta-D-lactosidase activity|downregulation of lactozym|inhibition of beta-D-lactosidase activity|downregulation of sumiklat|inhibition of beta-D-galactoside galactohydrolase activity|inhibition of maxilact|negative regulation of beta-D-galactoside galactohydrolase activity|downregulation of beta-D-lactosidase activity|negative regulation of beta-lactosidase activity|down-regulation of hydrolact|inhibition of beta-galactosidase activity|inhibition of lactozym|downregulation of trilactase activity|downregulation of exo-(1->4)-beta-D-galactanase activity|inhibition of oryzatym|inhibition of lactose hydrolysis|down-regulation of sumiklat|down regulation of maxilact|negative regulation of maxilact|inhibition of trilactase activity|negative regulation of beta-D-galactanase activity|inhibition of exo-(1->4)-beta-D-galactanase activity|down regulation of beta-D-lactosidase activity|downregulation of beta-galactosidase activity|down-regulation of beta-D-lactosidase activity|downregulation of S 2107|downregulation of beta-D-galactanase activity|down-regulation of beta-galactosidase activity|negative regulation of S 2107|down regulation of beta-galactosidase activity|negative regulation of trilactase activity|downregulation of oryzatym|negative regulation of sumiklat|down-regulation of lactozym|down-regulation of exo-(1->4)-beta-D-galactanase activity|downregulation of maxilact|down-regulation of lactose hydrolysis|down-regulation of oryzatym|negative regulation of lactozym|inhibition of beta-D-galactanase activity|inhibition of sumiklat|down regulation of beta-D-galactoside galactohydrolase activity|down-regulation of maxilact|down regulation of hydrolact|downregulation of beta-lactosidase activity|downregulation of hydrolact|down-regulation of beta-D-galactoside galactohydrolase activity|down regulation of beta-D-galactanase activity|down regulation of exo-(1->4)-beta-D-galactanase activity|down-regulation of trilactase activity|down regulation of lactozym|downregulation of beta-D-galactoside galactohydrolase activity|down-regulation of beta-lactosidase activity|down regulation of oryzatym|down regulation of S 2107|down regulation of lactose hydrolysis|down-regulation of beta-D-galactanase activity|negative regulation of hydrolact|inhibition of S 2107|inhibition of beta-lactosidase activity|inhibition of hydrolact|negative regulation of exo-(1->4)-beta-D-galactanase activity|negative regulation of oryzatym|down-regulation of S 2107|downregulation of lactose hydrolysis|down regulation of beta-lactosidase activity|negative regulation of lactose hydrolysis|down regulation of sumiklat|down regulation of trilactase activity							nc	2015-01-06T10:53:22Z					biological_process											owl:Class	
GO:1902516	biolink:NamedThing	sn-glycerol 3-phosphate binding	Binding to sn-glycerol 3-phosphate.	tmpzr1t_l9r_go_relaxed.owl						An example of this is UgpB in E. coli [P0AG80] - see PMID:23013274.		bhm	2013-11-27T16:50:55Z					molecular_function											owl:Class	
GO:1903218	biolink:NamedThing	regulation of malate dehydrogenase (decarboxylating) (NADP+) activity	Any process that modulates the frequency, rate or extent of malate dehydrogenase (decarboxylating) (NADP+) activity.	tmpzr1t_l9r_go_relaxed.owl	regulation of malate dehydrogenase (decarboxylating, NADP)|regulation of NADP-malic enzyme activity|regulation of L-malate:NADP oxidoreductase activity|regulation of NADP-specific malate dehydrogenase activity|regulation of malate dehydrogenase (NADP, decarboxylating)|regulation of 'malic' enzyme|regulation of NADP-linked decarboxylating malic enzyme|regulation of (S)-malate:NADP+ oxidoreductase (oxaloacetate-decarboxylating)|regulation of NADP-specific malic enzyme							sart	2014-07-24T11:17:22Z					biological_process											owl:Class	
GO:0008885	biolink:NamedThing	glutathionylspermidine synthase activity	Catalysis of the reaction: gamma-L-glutamyl-L-cysteinyl-glycine + spermidine + ATP = N1-(gamma-L-glutamyl-L-cysteinyl-glycyl)-spermidine + ADP + phosphate.	tmpzr1t_l9r_go_relaxed.owl	gamma-L-glutamyl-L-cysteinyl-glycine:spermidine ligase (ADP-forming) [spermidine is numbered so that atom N-1 is in the amino group of the aminopropyl part of the molecule]|glutathionylspermidine synthetase activity|GSP synthetase activity|gamma-L-glutamyl-L-cysteinyl-glycine:spermidine ligase (ADP-forming) activity|glutathione:spermidine ligase (ADP-forming) activity				MetaCyc:GSPSYN-RXN|RHEA:21272|EC:6.3.1.8									molecular_function											owl:Class	
GO:1901429	biolink:NamedThing	negative regulation of syringal lignin biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of syringal lignin biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	downregulation of syringal lignin anabolism|negative regulation of syringal lignin synthesis|inhibition of syringal lignin synthesis|down-regulation of S-lignin biosynthetic process|negative regulation of syringal lignin formation|inhibition of syringal lignin anabolism|inhibition of S-lignin biosynthetic process|down regulation of syringal lignin biosynthesis|negative regulation of syringal lignin biosynthesis|downregulation of syringal lignin synthesis|down regulation of syringal lignin formation|inhibition of syringal lignin biosynthetic process|down regulation of syringal lignin anabolism|downregulation of syringal lignin biosynthesis|down-regulation of syringal lignin synthesis|downregulation of syringal lignin biosynthetic process|downregulation of syringal lignin formation|negative regulation of syringal lignin anabolism|down regulation of syringal lignin synthesis|negative regulation of S-lignin biosynthetic process|inhibition of syringal lignin biosynthesis|down-regulation of syringal lignin biosynthesis|downregulation of S-lignin biosynthetic process|down-regulation of syringal lignin anabolism|down-regulation of syringal lignin formation|down regulation of syringal lignin biosynthetic process|inhibition of syringal lignin formation|down-regulation of syringal lignin biosynthetic process|down regulation of S-lignin biosynthetic process							tb	2012-10-01T20:14:51Z					biological_process											owl:Class	
GO:0032327	biolink:NamedThing	W-molybdopterin cofactor catabolic process	The chemical reactions and pathways resulting in the breakdown of the W-molybdopterin cofactor, essential for the catalytic activity of some enzymes. The cofactor consists of a mononuclear tungsten ion (W) coordinated by one or two molybdopterin ligands.	tmpzr1t_l9r_go_relaxed.owl	Moco catabolism|W-molybdopterin cofactor breakdown|Moco catabolic process|W-molybdopterin cofactor degradation|W-molybdopterin cofactor catabolism													biological_process											owl:Class	
GO:0051413	biolink:NamedThing	response to cortisone	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cortisone stimulus. Cortisone is a natural glucocorticoid steroid hormone that is metabolically convertible to cortisol. Cortisone is synthesized from cholesterol in the cortex of the adrenal gland under the stimulation of adrenocorticotropin hormone (ACTH). The main physiological effect of cortisone is on carbohydrate metabolism; it can stimulate increased glucose release from the liver, increased liver glycogen synthesis, and decreased utilization of glucose by the tissues.	tmpzr1t_l9r_go_relaxed.owl	response to cortisone stimulus													biological_process											owl:Class	
GO:0031872	biolink:NamedThing	type 1 proteinase activated receptor binding	Binding to a type 1 proteinase activated receptor.	tmpzr1t_l9r_go_relaxed.owl	type 1 proteinase activated receptor ligand|thrombin receptor binding													molecular_function											owl:Class	
GO:0047742	biolink:NamedThing	chenodeoxycholoyltaurine hydrolase activity	Catalysis of the reaction: chenodeoxycholoyltaurine + H2O = chenodeoxycholate + taurine.	tmpzr1t_l9r_go_relaxed.owl	chenodeoxycholoyltaurine amidohydrolase activity				RHEA:16309|MetaCyc:CHENODEOXYCHOLOYLTAURINE-HYDROLASE-RXN|EC:3.5.1.74									molecular_function											owl:Class	
GO:1990627	biolink:NamedThing	mitochondrial inner membrane fusion	The membrane organization process that joins two mitochondrial inner membranes to form a single membrane.	tmpzr1t_l9r_go_relaxed.owl	mitochondrion inner membrane fusion							vw	2015-02-02T11:37:56Z					biological_process											owl:Class	
GO:0102277	biolink:NamedThing	2-acetamido-4-O-(2-amino-2-deoxy-beta-D-glucopyranosyl)-2-deoxy-D-glucose exo-beta-D-glucosaminidase activity	Catalysis of the reaction: 2-acetamido-4-O-(2-amino-2-deoxy-beta-D-glucopyranosyl)-2-deoxy-D-glucose + H2O = N-acetyl-D-glucosamine + D-glucosamine.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-12544									molecular_function											owl:Class	
GO:0003243	biolink:NamedThing	circumferential growth involved in left ventricle morphogenesis	The morphogenetic growth in which the left ventricle grows expanding its external boundary.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-10-13T11:33:09Z					biological_process											owl:Class	
GO:0033677	biolink:NamedThing	DNA/RNA helicase activity	Unwinding of a DNA/RNA duplex, i.e. a double helix in which a strand of DNA pairs with a complementary strand of RNA, driven by ATP hydrolysis.	tmpzr1t_l9r_go_relaxed.owl	ATP-dependent DNA/RNA helicase activity	https://github.com/geneontology/go-ontology/issues/21612										GO:0033680		molecular_function											owl:Class	
GO:0046172	biolink:NamedThing	octanol catabolic process	The chemical reactions and pathways resulting in the breakdown of octanol, the 8-carbon alcohol with the formula C8H17OH.	tmpzr1t_l9r_go_relaxed.owl	octanol catabolism|octanol degradation|octanol breakdown													biological_process											owl:Class	
GO:0043189	biolink:NamedThing	H4/H2A histone acetyltransferase complex	A multisubunit complex that catalyzes the acetylation of histones H4 and H2A.	tmpzr1t_l9r_go_relaxed.owl	H4/H2A HAT complex													cellular_component											owl:Class	
GO:0060930	biolink:NamedThing	sinoatrial node cell fate commitment	The commitment of cells to sinoatrial (SA) node cell fates and their capacity to differentiate into SA node cells. SA node cells are pacemaker cells that are found in the sinoatrial node.	tmpzr1t_l9r_go_relaxed.owl	SAN cell commitment|sinus node cell commitment|SA node cell commitment							dph	2009-09-29T12:03:38Z					biological_process											owl:Class	
GO:0047956	biolink:NamedThing	glycerol dehydrogenase [NADP+] activity	Catalysis of the reaction: glycerol + NADP+ = D-glyceraldehyde + NADPH.	tmpzr1t_l9r_go_relaxed.owl	glycerol dehydrogenase (NADP+) activity|glycerol:NADP+ oxidoreductase activity				MetaCyc:GLYCEROL-DEHYDROGENASE-NADP+-RXN|RHEA:23592|EC:1.1.1.72									molecular_function											owl:Class	
GO:0051392	biolink:NamedThing	tRNA N-acetyltransferase activity	Catalysis of the reaction: acetyl-CoA + cytidine = CoA + N4-acetylcytidine. The cytidine is within the polynucleotide chain of a tRNA.	tmpzr1t_l9r_go_relaxed.owl	tRNA cytidine N-acetyltransferase activity													molecular_function											owl:Class	
GO:0061340	biolink:NamedThing	establishment or maintenance of monopolar cell polarity regulating cell shape	Any cellular process that results in the specification, formation or maintenance of a monopolar intracellular organization or cell growth patterns that regulate the shape of a cell.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-09-29T09:13:55Z					biological_process											owl:Class	
GO:0019981	biolink:NamedThing	interleukin-6 binding	Binding to interleukin-6.	tmpzr1t_l9r_go_relaxed.owl	IL-6 binding													molecular_function											owl:Class	
GO:0102920	biolink:NamedThing	acyl coenzyme A: isopenicillin N acyltransferase activity	Catalysis of the reaction: octanoyl-CoA + isopenicillin N + H2O <=> H+ + coenzyme A + penicillin K + L-2-aminoadipate.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-8809|EC:2.3.1.164									molecular_function											owl:Class	
GO:0120017	biolink:NamedThing	ceramide transfer activity	Removes a ceramide from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle.	tmpzr1t_l9r_go_relaxed.owl	ceramide carrier activity|ceramide transporter activity|intermembrane ceramide transfer activity	https://github.com/geneontology/go-ontology/issues/12329						krc	2010-12-08T12:32:50Z			GO:0035620		molecular_function											owl:Class	
GO:0052909	biolink:NamedThing	18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase activity	Catalysis of the reaction: 4 S-adenosyl-L-methionine + adenine(1779)/adenine(1780) in 18S rRNA = 4 S-adenosyl-L-homocysteine + N(6)-dimethyladenine(1779)/N(6)-dimethyladenine(1780) in 18S rRNA.	tmpzr1t_l9r_go_relaxed.owl	M(6)(2)A dimethylase activity	https://github.com/geneontology/go-ontology/issues/14459			RHEA:42780|MetaCyc:RXN-11634|EC:2.1.1.183									molecular_function											owl:Class	
GO:0102518	biolink:NamedThing	(11Z)-eicosenoate 14-hydroxylase activity	Catalysis of the reaction: (11Z)-eicosenoyl-CoA + NADH + O2 + H+ = lesqueroloyl-CoA + NAD + H2O.	tmpzr1t_l9r_go_relaxed.owl					EC:1.14.18.4|MetaCyc:RXN-14488									molecular_function											owl:Class	
GO:0102682	biolink:NamedThing	N6-(Delta2-isopentenyl)-adenosine 5'-monophosphate phosphoribohydrolase activity	Catalysis of the reaction: N(6)-(dimethylallyl)adenosine 5'-phosphate + H2O <=> N(6)-dimethylallyladenine + D-ribofuranose 5-phosphate.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-4313|RHEA:48560									molecular_function											owl:Class	
GO:0030246	biolink:NamedThing	carbohydrate binding	Binding to a carbohydrate, which includes monosaccharides, oligosaccharides and polysaccharides as well as substances derived from monosaccharides by reduction of the carbonyl group (alditols), by oxidation of one or more hydroxy groups to afford the corresponding aldehydes, ketones, or carboxylic acids, or by replacement of one or more hydroxy group(s) by a hydrogen atom. Cyclitols are generally not regarded as carbohydrates.	tmpzr1t_l9r_go_relaxed.owl	sugar binding|selectin											GO:0005529		molecular_function											owl:Class	
GO:0047106	biolink:NamedThing	4-hydroxyphenylacetaldehyde dehydrogenase activity	Catalysis of the reaction: NAD+ + (4-hydroxyphenyl)acetaldehyde + H2O = NADH + 4-hydroxyphenylacetate.	tmpzr1t_l9r_go_relaxed.owl	4-hydroxyphenylacetaldehyde:NAD+ oxidoreductase activity|4-HPAL dehydrogenase activity				RHEA:17273|MetaCyc:1.2.1.53-RXN|EC:1.2.1.53									molecular_function											owl:Class	
GO:0047182	biolink:NamedThing	alcohol O-cinnamoyltransferase activity	Catalysis of the reaction: an alcohol + 1-O-trans-cinnamoyl-beta-D-glucopyranose = beta-D-glucose + alkyl cinnamate.	tmpzr1t_l9r_go_relaxed.owl	1-O-trans-cinnamoyl-beta-D-glucopyranose:alcohol O-cinnamoyltransferase activity				MetaCyc:2.3.1.152-RXN|EC:2.3.1.152|RHEA:23524									molecular_function											owl:Class	
GO:0032871	biolink:NamedThing	regulation of karyogamy	Any process that modulates the frequency, rate or extent of karyogamy, the creation of a single nucleus from multiple nuclei as a result of membrane fusion.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:2000747	biolink:NamedThing	negative regulation of defecation rhythm	Any process that stops, prevents or reduces the frequency, rate or extent of defecation rhythm.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of DMP|negative regulation of defecation motor program|negative regulation of defecation cycle|negative regulation of defecation behavior							bf	2011-06-15T03:23:10Z					biological_process											owl:Class	
GO:0034057	biolink:NamedThing	RNA strand-exchange activity	Facilitates the displacement of one strand of an RNA-RNA duplex and its replacement with a different strand of higher complementarity.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0060530	biolink:NamedThing	smooth muscle cell differentiation involved in prostate glandular acinus development	The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell of the prostate glandular acinus.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:2001200	biolink:NamedThing	positive regulation of dendritic cell differentiation	Any process that activates or increases the frequency, rate or extent of dendritic cell differentiation.	tmpzr1t_l9r_go_relaxed.owl								yaf	2011-11-04T02:01:36Z					biological_process											owl:Class	
GO:0042385	biolink:NamedThing	myosin III complex	A myosin complex containing a class III myosin heavy chain and associated light chains; myosin III is monomeric myosin that serves as a link between the cytoskeleton and the signaling complex involved in phototransduction, and differs from all other myosins in having an N-terminal kinase domain.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0045151	biolink:NamedThing	acetoin biosynthetic process	The chemical reactions and pathways resulting in the formation of acetoin, 3-hydroxy-2-butanone.	tmpzr1t_l9r_go_relaxed.owl	acetoin formation|acetoin synthesis|acetoin biosynthesis|acetoin anabolism													biological_process											owl:Class	
GO:2000277	biolink:NamedThing	positive regulation of oxidative phosphorylation uncoupler activity	Any process that activates or increases the frequency, rate or extent of oxidative phosphorylation uncoupler activity.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of uncoupling protein activity|positive regulation of mitochondrial uncoupling protein activity							mah	2010-12-07T12:15:02Z					biological_process											owl:Class	
GO:1903515	biolink:NamedThing	calcium ion transport from cytosol to endoplasmic reticulum	The directed movement of calcium ion from cytosol to endoplasmic reticulum.	tmpzr1t_l9r_go_relaxed.owl								rl	2014-10-02T14:51:20Z					biological_process											owl:Class	
GO:0018414	biolink:NamedThing	nickel incorporation into metallo-sulfur cluster	The incorporation of nickel into a metallo-sulfur cluster.	tmpzr1t_l9r_go_relaxed.owl	nickel incorporation into metallo-sulphur cluster													biological_process											owl:Class	
GO:0034517	biolink:NamedThing	ribophagy	The selective autophagy process in which cells degrade mature ribosomes under conditions of starvation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0045315	biolink:NamedThing	positive regulation of compound eye photoreceptor development	Any process that activates or increases the frequency, rate or extent of compound eye photoreceptor development.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of eye photoreceptor development|activation of eye photoreceptor development|stimulation of eye photoreceptor development|up regulation of eye photoreceptor development|upregulation of eye photoreceptor development|positive regulation of eye photoreceptor development													biological_process											owl:Class	
GO:0050207	biolink:NamedThing	plasmanylethanolamine desaturase activity	Catalysis of the reaction: O-1-alkyl-2-acyl-sn-glycero-3-phosphoethanolamine + donor-H2 + O2 = O-1-alk-1-enyl-2-acyl-sn-glycero-3-phosphoethanolamine + acceptor + 2 H2O.	tmpzr1t_l9r_go_relaxed.owl	alkylacylglycerophosphoethanolamine desaturase activity|alkylacylglycero-phosphorylethanolamine dehydrogenase activity|O-1-alkyl-2-acyl-sn-glycero-3-phosphoethanolamine,hydrogen-donor:oxygen oxidoreductase activity|1-O-alkyl-2-acyl-sn-glycero-3-phosphorylethanolamine desaturase activity|1-O-alkyl 2-acyl-sn-glycero-3-phosphorylethanolamine desaturase activity|dehydrogenase, alkyl-acylglycerophosphorylethanolamine|plasmenylethanolamine desaturase activity				RHEA:22956|MetaCyc:PLASMANYLETHANOLAMINE-DESATURASE-RXN|EC:1.14.19.77									molecular_function											owl:Class	
GO:0071195	biolink:NamedThing	Kv4.2-KChIP4 channel complex	A voltage-gated potassium channel complex that contains the Kv channel interacting protein KChIP4 associated with the channel via interaction with the Kv alpha subunit 4.2.	tmpzr1t_l9r_go_relaxed.owl					CORUM:3090			mah	2009-11-23T04:59:06Z					cellular_component											owl:Class	
GO:1903392	biolink:NamedThing	negative regulation of adherens junction organization	Any process that stops, prevents or reduces the frequency, rate or extent of adherens junction organization.	tmpzr1t_l9r_go_relaxed.owl	inhibition of adherens junction organisation|down regulation of adherens junction organisation|negative regulation of adherens junction assembly and maintenance|inhibition of adherens junction organization|down-regulation of adherens junction assembly and maintenance|downregulation of adherens junction assembly and maintenance|down regulation of adherens junction assembly and maintenance|downregulation of adherens junction organization|downregulation of adherens junction organisation|down regulation of adherens junction organization|negative regulation of adherens junction organisation|down-regulation of adherens junction organisation|inhibition of adherens junction assembly and maintenance|down-regulation of adherens junction organization							als	2014-08-27T10:08:47Z					biological_process											owl:Class	
GO:0045438	biolink:NamedThing	delta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine synthetase activity	Catalysis of the formation of delta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine from constituent amino acids and ATP in the presence of magnesium ions and dithioerythritol.	tmpzr1t_l9r_go_relaxed.owl	ACV synthetase activity													molecular_function											owl:Class	
GO:0047387	biolink:NamedThing	serine-ethanolaminephosphate phosphodiesterase activity	Catalysis of the reaction: H(2)O + serine phosphoethanolamine = H(+) + phosphoethanolamine + serine.	tmpzr1t_l9r_go_relaxed.owl	serine ethanolamine phosphodiester phosphodiesterase activity|SEP diesterase activity|serine-phosphoethanolamine ethanolaminephosphohydrolase activity				MetaCyc:3.1.4.13-RXN|KEGG_REACTION:R02817|EC:3.1.4.13|RHEA:17113									molecular_function											owl:Class	
GO:0103062	biolink:NamedThing	cis-keto-C60-meroacyl-AMP ligase activity	Catalysis of the reaction: ATP(4-) + H2O + a cis-keto-C60-meroacyl-[acp] <=> diphosphoric acid + a cis-keto-meroacyl-adenylate + a holo-[acyl-carrier protein].	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN1G-4142									molecular_function											owl:Class	
GO:0018069	biolink:NamedThing	peptide cross-linking via 4'-(L-tryptophan)-L-tryptophyl quinone	The cross-linking of a tryptophan residue to tryptophyl quinone to form 4'-(L-tryptophan)-L-tryptophyl quinone, a cofactor found at the active site of methylamine dehydrogenase.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0149									biological_process											owl:Class	
GO:0060877	biolink:NamedThing	regionalization involved in semicircular canal formation	The pattern specification process that results in the subdivision of the otic epithelium in space to define an area or volume in which cells will differentiate to give rise to the semicircular canals.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-08-13T09:56:45Z					biological_process											owl:Class	
GO:0099400	biolink:NamedThing	caveola neck	A membrane microdomain that forms a necklace around the bulb (crater) of a caveola.  Intramembrane particles are concentrated in this region and cytoskeletal components, including actin, are highly enriched in the area underlying it.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0098857	biolink:NamedThing	membrane microdomain	A membrane region with a lipid composition that is distinct from that of the membrane regions that surround it.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0061406	biolink:NamedThing	positive regulation of transcription from RNA polymerase II promoter in response to glucose starvation	Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of deprivation of glucose.	tmpzr1t_l9r_go_relaxed.owl								dph	2012-01-12T11:16:10Z					biological_process											owl:Class	
GO:0007253	biolink:NamedThing	cytoplasmic sequestering of NF-kappaB	The selective interaction of the transcription factor NF-kappaB with specific molecules in the cytoplasm, thereby inhibiting its translocation into the nucleus.	tmpzr1t_l9r_go_relaxed.owl	cytoplasmic storage of NF-kappaB|cytoplasmic sequestration of NF-kappaB|cytoplasmic NF-kappaB retention|cytoplasmic NF-kappaB sequestration|cytoplasmic NF-kappaB storage|cytoplasmic retention of NF-kappaB|maintenance of NF-kappaB location in cytoplasm													biological_process											owl:Class	
GO:0032088	biolink:NamedThing	negative regulation of NF-kappaB transcription factor activity	Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of the transcription factor NF-kappaB.	tmpzr1t_l9r_go_relaxed.owl	NF-kappaB inhibitor|inhibition of NF-kappaB transcription factor													biological_process											owl:Class	
GO:0035095	biolink:NamedThing	behavioral response to nicotine	Any process that results in a change in the behavior of an organism as a result of a nicotine stimulus.	tmpzr1t_l9r_go_relaxed.owl	behavioural response to nicotine													biological_process											owl:Class	
GO:0008972	biolink:NamedThing	phosphomethylpyrimidine kinase activity	Catalysis of the reaction: ATP + 4-amino-2-methyl-5-phosphomethylpyrimidine = ADP + 4-amino-2-methyl-5-diphosphomethylpyrimidine.	tmpzr1t_l9r_go_relaxed.owl	ATP:4-amino-2-methyl-5-phosphomethylpyrimidine phosphotransferase activity|hydroxymethylpyrimidine phosphokinase activity				RHEA:19893|MetaCyc:PYRIMSYN3-RXN|EC:2.7.4.7									molecular_function											owl:Class	
GO:0015935	biolink:NamedThing	small ribosomal subunit	The smaller of the two subunits of a ribosome.	tmpzr1t_l9r_go_relaxed.owl	ribosomal small subunit													cellular_component											owl:Class	
GO:0005001	biolink:NamedThing	transmembrane receptor protein tyrosine phosphatase activity	Combining with a signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: protein tyrosine phosphate + H2O = protein tyrosine + phosphate.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0010198	biolink:NamedThing	synergid death	Synergid cells undergo degeneration and death in response to penetration by the pollen tube. It is an active process that involves a dramatic decrease in cell volume, collapse of the vacuoles, and complete disintegration of the plasma membrane and most organelles.	tmpzr1t_l9r_go_relaxed.owl	synergid cell death|synergid degeneration											GO:0048470		biological_process											owl:Class	
GO:0035102	biolink:NamedThing	PRC1 complex	A multiprotein complex that mediates monoubiquitination of lysine residues of histone H2A (lysine-118 in Drosophila or lysine-119 in mammals). The complex is required for stable long-term maintenance of transcriptionally repressed states and is involved in chromatin remodeling.	tmpzr1t_l9r_go_relaxed.owl	Polycomb repressive complex 1					In Drosophila the core subunits are Pc (Polycomb), Psc (Posterior sex combs), Ph (Polyhomeotic) and Sce (Sex comb extra). In mammals, which have several orthologs for each of the Drosophila core proteins, a family of distinct PRC1-like complexes seem to exist which contain at least some PcG proteins in mutually exclusive manner.								cellular_component											owl:Class	
GO:0030127	biolink:NamedThing	COPII vesicle coat	One of two multimeric complexes that forms a membrane vesicle coat. COPII is best characterized in S. cerevisiae, where the subunits are called Sar1p, Sec13p, Sec31p, Sec23p, and Sec24p. Vesicles with COPII coats are found associated with endoplasmic reticulum (ER) membranes at steady state.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0010747	biolink:NamedThing	positive regulation of long-chain fatty acid import across plasma membrane	Any process that increases the rate, frequency or extent of plasma membrane long-chain fatty acid transport. Plasma membrane long-chain fatty acid transport is the directed movement of long-chain fatty acids across the plasma membrane. A long-chain fatty acid is a fatty acid with a chain length between C13 and C22.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of plasma membrane long-chain fatty acid transport													biological_process											owl:Class	
GO:0047546	biolink:NamedThing	2-hydroxypyridine 5-monooxygenase activity	Catalysis of the reaction: 2-hydroxypyridine + AH(2) + O(2) = 2,5-dihydroxypyridine + A + H(2)O.	tmpzr1t_l9r_go_relaxed.owl	2-hydroxypyridine oxygenase activity|2-hydroxypyridine,hydrogen-donor:oxygen oxidoreductase (5-hydroxylating)				KEGG_REACTION:R03206|MetaCyc:2-HYDROXYPYRIDINE-5-MONOOXYGENASE-RXN|EC:1.14.99.26|RHEA:16973									molecular_function											owl:Class	
GO:1904186	biolink:NamedThing	post-anaphase microtubule array organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly ofa post-anaphase microtubule array.	tmpzr1t_l9r_go_relaxed.owl	post-anaphase array organization|post-anaphase microtubule array organisation|PAA organization							mah	2015-05-05T14:40:16Z					biological_process											owl:Class	
GO:0035018	biolink:NamedThing	adult chitin-based cuticle pattern formation	The process that gives rise to the patterns of cell differentiation that will arise in the chitin-based adult cuticle. An example of this process is adult chitin-based cuticle pattern formation in Drosophila melanogaster.	tmpzr1t_l9r_go_relaxed.owl	adult cuticle pattern formation													biological_process											owl:Class	
GO:0044534	biolink:NamedThing	envenomation resulting in modulation of apoptotic process in other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant modulation of apoptosis in the bitten organism.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-03-21T11:39:44Z					biological_process											owl:Class	
GO:0102655	biolink:NamedThing	1-18:1-2-trans-16:1-phosphatidylglycerol desaturase activity	Catalysis of the reaction: 1-18:1-2-trans-16:1-phosphatidylglycerol + O2 + a reduced electron acceptor <=> 1-18:2-2-trans-16:1-phosphatidylglycerol + 2 H2O + an oxidized electron acceptor.	tmpzr1t_l9r_go_relaxed.owl					EC:1.14.19.23|MetaCyc:RXN-1726									molecular_function											owl:Class	
GO:0140132	biolink:NamedThing	iron-sulfur cluster carrier activity	Binding to an iron-sulfur cluster and delivering it to an acceptor molecule.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/14539						pg	2017-11-10T08:55:38Z					molecular_function											owl:Class	
GO:0008240	biolink:NamedThing	tripeptidyl-peptidase activity	Catalysis of the release of an N-terminal tripeptide from a polypeptide.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/19681			MetaCyc:3.4.14.10-RXN|MetaCyc:3.4.14.9-RXN|EC:3.4.14.9|EC:3.4.14.10									molecular_function											owl:Class	
GO:0046655	biolink:NamedThing	folic acid metabolic process	The chemical reactions and pathways involving folic acid, pteroylglutamic acid. Folic acid is widely distributed as a member of the vitamin B complex and is essential for the synthesis of purine and pyrimidines.	tmpzr1t_l9r_go_relaxed.owl	vitamin M metabolic process|vitamin M metabolism|folate metabolism|vitamin B9 metabolism|folate metabolic process|vitamin B9 metabolic process|folic acid metabolism													biological_process											owl:Class	
GO:1904277	biolink:NamedThing	negative regulation of wax biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of wax biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of wax synthesis|downregulation of wax formation|down-regulation of wax synthesis|down regulation of wax biosynthesis|down regulation of wax biosynthetic process|down regulation of wax anabolism|downregulation of wax synthesis|down regulation of wax formation|inhibition of wax biosynthetic process|down-regulation of wax formation|down-regulation of wax biosynthesis|negative regulation of wax biosynthesis|downregulation of wax biosynthesis|inhibition of wax biosynthesis|down-regulation of wax anabolism|down regulation of wax synthesis|negative regulation of wax anabolism|negative regulation of wax formation|downregulation of wax anabolism|inhibition of wax formation|down-regulation of wax biosynthetic process|downregulation of wax biosynthetic process|inhibition of wax synthesis|inhibition of wax anabolism							tb	2015-06-03T17:20:13Z					biological_process											owl:Class	
GO:0090130	biolink:NamedThing	tissue migration	The process in which the population of cells that make up a tissue undergo directed movement.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-12-07T03:13:55Z					biological_process											owl:Class	
GO:1900482	biolink:NamedThing	positive regulation of diacylglycerol biosynthetic process	Any process that activates or increases the frequency, rate or extent of diacylglycerol biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	upregulation of diacylglycerol anabolism|up-regulation of diacylglycerol biosynthesis|activation of diacylglycerol anabolism|positive regulation of diacylglycerol biosynthesis|upregulation of diacylglycerol synthesis|positive regulation of diacylglycerol formation|upregulation of diacylglycerol biosynthesis|up regulation of diacylglycerol synthesis|up regulation of diacylglycerol biosynthesis|activation of diacylglycerol formation|upregulation of diacylglycerol formation|up-regulation of diacylglycerol biosynthetic process|up-regulation of diacylglycerol formation|up-regulation of diacylglycerol anabolism|up regulation of diacylglycerol anabolism|up regulation of diacylglycerol biosynthetic process|activation of diacylglycerol biosynthesis|up regulation of diacylglycerol formation|activation of diacylglycerol synthesis|up-regulation of diacylglycerol synthesis|positive regulation of diacylglycerol synthesis|positive regulation of diacylglycerol anabolism|activation of diacylglycerol biosynthetic process|upregulation of diacylglycerol biosynthetic process							al	2012-05-02T10:09:18Z					biological_process											owl:Class	
GO:0102100	biolink:NamedThing	mycothiol-arsenate ligase activity	Catalysis of the reaction: arsenate + mycothiol <=> mycothiol-arsenate conjugate + H2O.	tmpzr1t_l9r_go_relaxed.owl					EC:2.8.4.2|MetaCyc:RXN-11187|RHEA:27349									molecular_function											owl:Class	
GO:0050497	biolink:NamedThing	alkylthioltransferase activity	Catalysis of the transfer of an alkylthio group from one compound (donor) to another (acceptor).	tmpzr1t_l9r_go_relaxed.owl	transferase activity, transferring alkylthio groups				EC:2.8.4.-									molecular_function											owl:Class	
GO:0046120	biolink:NamedThing	deoxyribonucleoside biosynthetic process	The chemical reactions and pathways resulting in the formation of any one of a family of organic molecules consisting of a purine or pyrimidine base covalently bonded to a sugar deoxyribose (a deoxyribonucleoside).	tmpzr1t_l9r_go_relaxed.owl	deoxyribonucleoside synthesis|deoxyribonucleoside formation|deoxyribonucleoside anabolism|deoxyribonucleoside biosynthesis													biological_process											owl:Class	
GO:0097209	biolink:NamedThing	epidermal lamellar body	A specialized secretory organelle found in keratinocytes and involved in the formation of an impermeable, lipid-containing membrane that serves as a water barrier and is required for correct skin barrier function.	tmpzr1t_l9r_go_relaxed.owl								pr	2012-01-04T02:34:27Z					cellular_component											owl:Class	
GO:0075120	biolink:NamedThing	suppression by symbiont of host G protein-coupled receptor signal transduction	Any process in which the symbiont stops, prevents, or reduces the frequency, rate or extent of the host G protein-coupled receptor signal transduction. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	negative regulation by symbiont of host G-protein coupled receptor protein signal transduction|negative regulation by symbiont of host signal transduction mediated by G-protein beta subunit|negative regulation by symbiont of host signal transduction mediated by G-protein alpha subunit|negative regulation by symbiont of host signal transduction mediated by G-protein gamma subunit|negative regulation by symbiont of host G protein-coupled receptor signal transduction					Note that this term is used to annotate gene products of the symbiont. To annotate host gene products, consider the biological process term "negative regulation by host of symbiont G protein-coupled receptor signal transduction ; GO:0075089".						GO:0075126|GO:0075123|GO:0075129		biological_process											owl:Class	
GO:0070681	biolink:NamedThing	glutaminyl-tRNAGln biosynthesis via transamidation	A tRNA aminoacylation process in which glutaminyl-tRNAGln is formed by a tRNA-dependent two-step pathway. In the first step a non-discriminating glutamyl-tRNAGlx synthetase generates the misacylated L-glutamyl-tRNAGln species, and in the second step it is amidated to the correctly charged L-glutaminyl-tRNAGln by a glutamyl-tRNAGln amidotransferase.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:PWY-5921			mah	2009-06-02T03:15:57Z					biological_process											owl:Class	
GO:0030116	biolink:NamedThing	glial cell-derived neurotrophic factor receptor binding	A growth factor that binds selectively and non-covalently to glial cell-derived neurotrophic factor receptors.	tmpzr1t_l9r_go_relaxed.owl	glial cell line-derived neurotrophic factor receptor ligand|glial cell line-derived neurotrophic factor receptor binding													molecular_function											owl:Class	
GO:0045343	biolink:NamedThing	regulation of MHC class I biosynthetic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of MHC class I.	tmpzr1t_l9r_go_relaxed.owl	regulation of MHC class I formation|regulation of major histocompatibility complex class I biosynthesis|regulation of MHC class I biosynthesis|regulation of MHC class I synthesis|regulation of major histocompatibility complex class I biosynthetic process|regulation of MHC class I anabolism													biological_process											owl:Class	
GO:0018882	biolink:NamedThing	(+)-camphor metabolic process	The chemical reactions and pathways involving (+)-camphor, a bicyclic monoterpene ketone which is one of the major components in the leaves of common sage. Camphor exists in two enantiomers, but the (+)-isomer is more widely distributed.	tmpzr1t_l9r_go_relaxed.owl	camphor metabolic process|camphor metabolism|(+)-camphor metabolism				UM-BBD_pathwayID:cam									biological_process											owl:Class	
GO:2000614	biolink:NamedThing	positive regulation of thyroid-stimulating hormone secretion	Any process that activates or increases the frequency, rate or extent of thyroid-stimulating hormone secretion.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of TSH secretion|positive regulation of thyroid stimulating hormone secretion							yaf	2011-04-18T12:56:22Z					biological_process											owl:Class	
GO:0033408	biolink:NamedThing	UCG codon-amino acid adaptor activity	A triplet codon-amino acid adaptor activity that recognizes a UCG codon.	tmpzr1t_l9r_go_relaxed.owl	TCG codon-amino acid adaptor activity|serine tRNA					Note that in the standard genetic code, TCG codes for serine.								molecular_function											owl:Class	
GO:0018284	biolink:NamedThing	iron incorporation into protein via tetrakis-L-cysteinyl iron	The incorporation of iron into a protein via tetrakis-L-cysteinyl iron (there is no exogenous sulfur, so this modification by itself does not produce an iron-sulfur protein).	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0136									biological_process											owl:Class	
GO:0090560	biolink:NamedThing	2-(3-amino-3-carboxypropyl)histidine synthase activity	Catalysis of the reaction S-adenosyl-L-methionine + L-histidine-[translation elongation factor 2] = S-methyl-5-thioadenosine + 2-[(3S)-3-amino-3-carboxypropyl]-L-histidine-[translation elongation factor 2].	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-11371|Reactome:R-HSA-5358494|RHEA:36783			tb	2014-03-27T14:58:50Z					molecular_function											owl:Class	
GO:1905293	biolink:NamedThing	negative regulation of neural crest cell differentiation	Any process that stops, prevents or reduces the frequency, rate or extent of neural crest cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of neural crest cell differentiation|down regulation of neural crest cell differentiation|downregulation of neural crest cell differentiation|inhibition of neural crest cell differentiation							rl	2016-06-28T15:02:09Z					biological_process											owl:Class	
GO:1905403	biolink:NamedThing	negative regulation of activated CD8-positive, alpha-beta T cell apoptotic process	Any process that stops, prevents or reduces the frequency, rate or extent of activated CD8-positive, alpha-beta T cell apoptotic process.	tmpzr1t_l9r_go_relaxed.owl	downregulation of activated CD8-positive, alpha-beta T lymphocyte apoptotic process|inhibition of activated CD8-positive, alpha-beta T lymphocyte apoptotic process|down regulation of activated CD8-positive, alpha-beta T lymphocyte apoptosis|negative regulation of activated CD8-positive, alpha-beta T lymphocyte apoptosis|negative regulation of activated CD8-positive, alpha-beta T cell apoptosis|down regulation of activated CD8-positive, alpha-beta T-cell apoptosis|down regulation of activated CD8-positive, alpha-beta T-lymphocyte apoptosis|down regulation of activated CD8-positive, alpha-beta T lymphocyte apoptotic process|downregulation of activated CD8-positive, alpha-beta T-lymphocyte apoptotic process|negative regulation of activated CD8-positive, alpha-beta T-lymphocyte apoptotic process|down-regulation of activated CD8-positive, alpha-beta T-cell apoptotic process|downregulation of activated CD8-positive, alpha-beta T lymphocyte apoptosis|downregulation of activated CD8-positive, alpha-beta T-cell apoptosis|downregulation of activated CD8-positive, alpha-beta T-cell apoptotic process|down-regulation of activated CD8-positive, alpha-beta T-lymphocyte apoptotic process|down-regulation of activated CD8-positive, alpha-beta T lymphocyte apoptotic process|inhibition of activated CD8-positive, alpha-beta T-cell apoptosis|downregulation of activated CD8-positive, alpha-beta T cell apoptotic process|inhibition of activated CD8-positive, alpha-beta T cell apoptosis|inhibition of activated CD8-positive, alpha-beta T cell apoptotic process|downregulation of activated CD8-positive, alpha-beta T-lymphocyte apoptosis|inhibition of activated CD8-positive, alpha-beta T lymphocyte apoptosis|down regulation of activated CD8-positive, alpha-beta T cell apoptotic process|inhibition of activated CD8-positive, alpha-beta T-lymphocyte apoptotic process|down-regulation of activated CD8-positive, alpha-beta T cell apoptosis|down-regulation of activated CD8-positive, alpha-beta T-lymphocyte apoptosis|inhibition of activated CD8-positive, alpha-beta T-lymphocyte apoptosis|inhibition of activated CD8-positive, alpha-beta T-cell apoptotic process|down regulation of activated CD8-positive, alpha-beta T cell apoptosis|downregulation of activated CD8-positive, alpha-beta T cell apoptosis|negative regulation of activated CD8-positive, alpha-beta T-cell apoptotic process|down regulation of activated CD8-positive, alpha-beta T-cell apoptotic process|down-regulation of activated CD8-positive, alpha-beta T lymphocyte apoptosis|down-regulation of activated CD8-positive, alpha-beta T-cell apoptosis|down regulation of activated CD8-positive, alpha-beta T-lymphocyte apoptotic process|negative regulation of activated CD8-positive, alpha-beta T lymphocyte apoptotic process|negative regulation of activated CD8-positive, alpha-beta T-cell apoptosis|down-regulation of activated CD8-positive, alpha-beta T cell apoptotic process|negative regulation of activated CD8-positive, alpha-beta T-lymphocyte apoptosis							pga	2016-08-25T09:14:03Z					biological_process											owl:Class	
GO:0018649	biolink:NamedThing	tetrahydrofuran hydroxylase activity	Catalysis of the reaction: tetrahydrofuran + O2 + 2 H+ + 2 e- = H2O + 2-hydroxytetrahydrofuran.	tmpzr1t_l9r_go_relaxed.owl					EC:1.14.13.-|UM-BBD_reactionID:r0017									molecular_function											owl:Class	
GO:0007497	biolink:NamedThing	posterior midgut development	The process whose specific outcome is the progression of the posterior midgut over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1901676	biolink:NamedThing	positive regulation of histone H3-K27 acetylation	Any process that activates or increases the frequency, rate or extent of histone H3-K27 acetylation.	tmpzr1t_l9r_go_relaxed.owl	upregulation of histone H3 acetylation at K27|up regulation of histone H3-K27 acetylation|up regulation of histone H3 acetylation at K27|up-regulation of histone H3-K27 acetylation|activation of histone H3-K27 acetylation|up-regulation of histone H3 acetylation at K27|positive regulation of histone H3 acetylation at K27|up regulation of histone H3K27 acetylation|up-regulation of histone H3K27 acetylation|positive regulation of histone H3K27 acetylation|activation of histone H3K27 acetylation|upregulation of histone H3K27 acetylation|activation of histone H3 acetylation at K27|upregulation of histone H3-K27 acetylation							vk	2012-11-22T12:06:45Z					biological_process											owl:Class	
GO:0005835	biolink:NamedThing	fatty acid synthase complex	A multienzyme complex that catalyses the synthesis of fatty acids from acetyl CoA.	tmpzr1t_l9r_go_relaxed.owl	cytosolic type I fatty acid synthase complex|fatty acid synthetase complex|cytosolic FAS complex|FAS complex|cytosolic type I FAS complex|cytosolic fatty acid synthase complex|holo-[acyl-carrier-protein] synthase complex				Wikipedia:Fatty_acid_synthetase_complex							GO:0031374|GO:0031373		cellular_component											owl:Class	
GO:0050556	biolink:NamedThing	deacetylisoipecoside synthase activity	Catalysis of the reaction: deacetylisoipecoside + H(2)O = dopamine + secologanin.	tmpzr1t_l9r_go_relaxed.owl	deacetylisoipecoside dopamine-lyase (secologanin-forming)|deacetylisoipecoside dopamine-lyase activity				RHEA:21756|KEGG_REACTION:R05750|EC:4.3.3.3|MetaCyc:4.3.3.3-RXN									molecular_function											owl:Class	
GO:0015311	biolink:NamedThing	monoamine:proton antiporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + monoamine(in) = H+(in) + monoamine(out).	tmpzr1t_l9r_go_relaxed.owl	monoamine:hydrogen antiporter activity													molecular_function											owl:Class	
GO:2000414	biolink:NamedThing	negative regulation of fibronectin-dependent thymocyte migration	Any process that stops, prevents or reduces the frequency, rate or extent of fibronectin-dependent thymocyte migration.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of fibronectin-dependent thymic lymphocyte migration|negative regulation of fibronectin-dependent immature T lymphocyte migration|negative regulation of fibronectin-dependent immature T-lymphocyte migration|negative regulation of fibronectin-dependent immature T-cell migration|negative regulation of fibronectin-dependent immature T cell migration							mah	2011-02-23T01:38:37Z					biological_process											owl:Class	
GO:0002881	biolink:NamedThing	negative regulation of chronic inflammatory response to non-antigenic stimulus	Any process that stops, prevents, or reduces the frequency, rate, or extent of a chronic inflammatory response to a non-antigenic stimulus.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of chronic inflammatory response to non-antigenic stimulus|down regulation of chronic inflammatory response to non-antigenic stimulus|downregulation of chronic inflammatory response to non-antigenic stimulus|inhibition of chronic inflammatory response to non-antigenic stimulus													biological_process											owl:Class	
GO:1905443	biolink:NamedThing	regulation of clathrin coat assembly	Any process that modulates the frequency, rate or extent of clathrin coat assembly.	tmpzr1t_l9r_go_relaxed.owl	regulation of clathrin cage assembly							bf	2016-09-15T14:38:22Z					biological_process											owl:Class	
GO:0022872	biolink:NamedThing	protein-N(PI)-phosphohistidine-mannitol phosphotransferase system transmembrane transporter activity	Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + mannitol(out) = protein histidine + mannitol phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.	tmpzr1t_l9r_go_relaxed.owl	mannitol PTS transporter activity													molecular_function											owl:Class	
GO:0042589	biolink:NamedThing	zymogen granule membrane	The lipid bilayer surrounding a zymogen granule.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0003873	biolink:NamedThing	6-phosphofructo-2-kinase activity	Catalysis of the reaction: beta-D-fructose 6-phosphate + ATP = beta-D-fructose 2,6-bisphosphate + ADP + 2 H(+).	tmpzr1t_l9r_go_relaxed.owl	6-phosphofructose 2-kinase activity|6-phosphofructo-2-kinase (phosphorylating)|ATP:D-fructose-6-phosphate 2-phosphotransferase activity|fructose 6-phosphate 2-kinase activity|ATP:beta-D-fructose-6-phosphate 2-phosphotransferase activity|phosphofructokinase 2 activity				Reactome:R-HSA-71802|RHEA:15653|MetaCyc:6-PHOSPHOFRUCTO-2-KINASE-RXN|KEGG_REACTION:R02732|EC:2.7.1.105									molecular_function											owl:Class	
GO:0006700	biolink:NamedThing	C21-steroid hormone biosynthetic process	The chemical reactions and pathways resulting in the formation of C21-steroid hormones, steroid compounds containing 21 carbons which function as hormones.	tmpzr1t_l9r_go_relaxed.owl	C21-steroid hormone synthesis|C21-steroid hormone anabolism|C21-steroid hormone biosynthesis|C21-steroid hormone formation													biological_process											owl:Class	
GO:0002189	biolink:NamedThing	ribose phosphate diphosphokinase complex	A protein complex having ribose phosphate diphosphokinase activity.	tmpzr1t_l9r_go_relaxed.owl	phosphoribosylpyrophosphate synthetase complex|PRPP synthetase complex					In mammals, the complex consists of two non-identical catalytic subunits and two non-identical regulatory subunits.		hjd	2011-06-27T02:49:33Z					cellular_component											owl:Class	
GO:2001070	biolink:NamedThing	starch binding	Binding to starch.	tmpzr1t_l9r_go_relaxed.owl	amylum binding|amidon binding							jl	2011-09-14T12:02:50Z					molecular_function											owl:Class	
GO:2000729	biolink:NamedThing	positive regulation of mesenchymal cell proliferation involved in ureter development	Any process that activates or increases the frequency, rate or extent of mesenchymal cell proliferation involved in ureter development.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of ureteral mesenchymal cell proliferation|positive regulation of ureter mesenchymal cell proliferation							yaf	2011-06-10T02:27:19Z					biological_process											owl:Class	
GO:0052391	biolink:NamedThing	induction by symbiont of defense-related host calcium ion flux	The activation by an organism of a flux of calcium ions that occurs as part of the defense response of a host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	induction by organism of host Ca2+ flux|positive regulation by organism of defense-related calcium ion flux in other organism involved in symbiotic interaction|positive regulation by organism of defense-related host Ca2+ flux|up-regulation by symbiont of defense-related host calcium ion flux|stimulation by symbiont of defense-related host calcium ion flux|activation by organism of host calcium ion flux|upregulation by symbiont of defense-related host calcium ion flux|positive regulation by symbiont of defense-related host calcium ion flux|activation by symbiont of defense-related host calcium ion flux|activation by organism of host Ca2+ flux|up regulation by symbiont of defense-related host calcium ion flux|induction by organism of defense-related calcium ion flux in other organism involved in symbiotic interaction											GO:0052065|GO:0052389|GO:0052265		biological_process											owl:Class	
GO:0072738	biolink:NamedThing	cellular response to diamide	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diamide (N,N,N',N'-tetramethyldiazene-1,2-dicarboxamide) stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to N,N,N',N'-tetramethyldiazene-1,2-dicarboxamide							mah	2012-07-17T10:33:00Z					biological_process											owl:Class	
GO:0072737	biolink:NamedThing	response to diamide	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diamide (N,N,N',N'-tetramethyldiazene-1,2-dicarboxamide) stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to N,N,N',N'-tetramethyldiazene-1,2-dicarboxamide							mah	2012-07-17T10:33:00Z					biological_process											owl:Class	
GO:0097436	biolink:NamedThing	entry into dormancy	The dormancy process that results in entry into dormancy. Dormancy (sometimes called a dormant state) is a suspension of most physiological activity and growth that can be reactivated.	tmpzr1t_l9r_go_relaxed.owl	induction of dormancy							pr	2012-12-05T14:55:49Z					biological_process											owl:Class	
GO:0032227	biolink:NamedThing	negative regulation of synaptic transmission, dopaminergic	Any process that stops, prevents, or reduces the frequency, rate or extent of dopaminergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter dopamine.	tmpzr1t_l9r_go_relaxed.owl	inhibition of synaptic transmission, dopaminergic|down-regulation of synaptic transmission, dopaminergic|down regulation of synaptic transmission, dopaminergic|downregulation of synaptic transmission, dopaminergic													biological_process											owl:Class	
GO:0032225	biolink:NamedThing	regulation of synaptic transmission, dopaminergic	Any process that modulates the frequency, rate or extent of dopaminergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter dopamine.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0050422	biolink:NamedThing	strictosidine beta-glucosidase activity	Catalysis of the reaction: 3alpha(S)-strictosidine + H(2)O = D-glucose + strictosidine aglycone.	tmpzr1t_l9r_go_relaxed.owl	strictosidine beta-D-glucohydrolase activity|strictosidine b-glucosidase activity				MetaCyc:STRICTOSIDINE-BETA-GLUCOSIDASE-RXN|KEGG_REACTION:R03820|EC:3.2.1.105|RHEA:12917									molecular_function											owl:Class	
GO:0033552	biolink:NamedThing	response to vitamin B3	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin B3 stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to nicotinamide|response to niacin													biological_process											owl:Class	
GO:0005609	biolink:NamedThing	laminin-4 complex	A laminin complex composed of alpha2, beta2 and gamma1 polypeptide chains.	tmpzr1t_l9r_go_relaxed.owl	laminin-221 complex													cellular_component											owl:Class	
GO:1900601	biolink:NamedThing	endocrocin catabolic process	The chemical reactions and pathways resulting in the breakdown of endocrocin.	tmpzr1t_l9r_go_relaxed.owl	endocrocin catabolism|endocrocin degradation|endocrocin breakdown							di	2012-05-15T06:57:34Z					biological_process											owl:Class	
GO:0110066	biolink:NamedThing	negative regulation of interphase mitotic telomere clustering	Any process that stops, prevents, or reduces the frequency, rate or extent of mitotic telomere clustering during interphase.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of mitotic telomere clustering during interphase|telomere dispersion during interphase							kmv	2017-11-17T22:11:59Z					biological_process											owl:Class	
GO:0102680	biolink:NamedThing	campest-4-en-3-one hydroxylase activity	Catalysis of the reaction: H+ + campest-4-en-3-one + O2 + NADPH <=> (22S)-22-hydroxycampest-4-en-3-one + H2O + NADP.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-4231									molecular_function											owl:Class	
GO:0004952	biolink:NamedThing	dopamine neurotransmitter receptor activity	Combining with the neurotransmitter dopamine to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0021749	biolink:NamedThing	ventral cochlear nucleus development	The process whose specific outcome is the progression of the ventral cochlear nucleus over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0021747	biolink:NamedThing	cochlear nucleus development	The process whose specific outcome is the progression of the cochlear nucleus over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0032290	biolink:NamedThing	peripheral nervous system myelin formation	The process in which the wraps of cell membrane that constitute myelin are laid down around an axon by Schwann cells in the peripheral nervous system.	tmpzr1t_l9r_go_relaxed.owl	myelin formation in peripheral nervous system	https://github.com/geneontology/go-ontology/issues/19106												biological_process											owl:Class	
GO:0102824	biolink:NamedThing	UDP-L-rhamnose:quercetin 3-O-rhamnosyltransferase activity	Catalysis of the reaction: quercetin-7-olate + UDP-L-rhamnose <=> H+ + quercetin 3-O-rhamnoside + UDP.	tmpzr1t_l9r_go_relaxed.owl					RHEA:61160|MetaCyc:RXN-8267									molecular_function											owl:Class	
GO:0075199	biolink:NamedThing	positive regulation of symbiont haustorium neck formation for entry into host	Any process that activates, maintains or increases the frequency, rate or extent of symbiont haustorium neck formation for entry into host. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl						Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products from the symbiont involved in this process.								biological_process											owl:Class	
GO:0032090	biolink:NamedThing	Pyrin domain binding	Binding to a Pyrin (PAAD/DAPIN) domain, a protein-protein interaction domain that has the same fold as the Death domain.	tmpzr1t_l9r_go_relaxed.owl	PAAD domain binding|DAPIN domain binding													molecular_function											owl:Class	
GO:1905785	biolink:NamedThing	negative regulation of anaphase-promoting complex-dependent catabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of anaphase-promoting complex-dependent catabolic process.	tmpzr1t_l9r_go_relaxed.owl								vw	2017-01-09T10:16:23Z					biological_process											owl:Class	
GO:1905784	biolink:NamedThing	regulation of anaphase-promoting complex-dependent catabolic process	Any process that modulates the frequency, rate or extent of anaphase-promoting complex-dependent catabolic process.	tmpzr1t_l9r_go_relaxed.owl								vw	2017-01-09T10:16:14Z					biological_process											owl:Class	
GO:0032245	biolink:NamedThing	regulation of purine nucleoside transport	Any process that modulates the frequency, rate or extent of the directed movement of a purine nucleoside into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0061791	biolink:NamedThing	GTPase motor activity	A motor activity driven by GTP hydrolysis.	tmpzr1t_l9r_go_relaxed.owl								dph	2016-09-09T13:17:29Z					molecular_function											owl:Class	
GO:0047184	biolink:NamedThing	1-acylglycerophosphocholine O-acyltransferase activity	Catalysis of the reaction: 1-acyl-sn-glycero-3-phosphocholine + acyl-CoA = phosphatidylcholine + CoA.	tmpzr1t_l9r_go_relaxed.owl	acyl coenzyme A-monoacylphosphatidylcholine acyltransferase activity|lysolecithin acyltransferase activity|lysophosphatidylcholine acyltransferase activity|1-acyl-sn-glycero-3-phosphocholine acyltransferase activity|lysophosphatide acyltransferase activity|acyl-CoA:1-acyl-sn-glycero-3-phosphocholine O-acyltransferase activity|acyl-CoA:1-acyl-glycero-3-phosphocholine transacylase activity				Reactome:R-HSA-1482794|EC:2.3.1.23|MetaCyc:2.3.1.23-RXN|RHEA:12937							GO:0000507		molecular_function											owl:Class	
GO:0030215	biolink:NamedThing	semaphorin receptor binding	Binding to a semaphorin receptor.	tmpzr1t_l9r_go_relaxed.owl	plexin ligand|plexin binding|semaphorin receptor ligand													molecular_function											owl:Class	
GO:0045918	biolink:NamedThing	negative regulation of cytolysis	Any process that stops, prevents, or reduces the frequency, rate or extent of cytolysis.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of cytolysis|inhibition of cytolysis|down regulation of cytolysis|downregulation of cytolysis													biological_process											owl:Class	
GO:0005544	biolink:NamedThing	calcium-dependent phospholipid binding	Binding to a phospholipid, a class of lipids containing phosphoric acid as a mono- or diester, in the presence of calcium.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0097715	biolink:NamedThing	cellular response to viscosity	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a viscosity stimulus.	tmpzr1t_l9r_go_relaxed.owl								pr	2016-08-23T14:34:05Z					biological_process											owl:Class	
GO:0047465	biolink:NamedThing	N-acylglucosamine-6-phosphate 2-epimerase activity	Catalysis of the reaction: N-acyl-D-glucosamine 6-phosphate = N-acyl-D-mannosamine 6-phosphate.	tmpzr1t_l9r_go_relaxed.owl	N-acetylglucosmamine 6-phosphate 2-epimerase activity|N-acetylmannosamine-6-phosphate 2-epimerase activity|acylglucosamine-6-phosphate 2-epimerase activity|acylmannosamine phosphate 2-epimerase activity|N-acyl-D-glucosamine-6-phosphate 2-epimerase activity|acylglucosamine phosphate 2-epimerase activity				MetaCyc:5.1.3.9-RXN|EC:5.1.3.9|RHEA:23932									molecular_function											owl:Class	
GO:0050847	biolink:NamedThing	progesterone receptor signaling pathway	Any series of molecular signals generated as a consequence of a progesterone binding to its receptor.	tmpzr1t_l9r_go_relaxed.owl	progesterone receptor signalling pathway													biological_process											owl:Class	
GO:0021964	biolink:NamedThing	rubrospinal tract morphogenesis	Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the red nucleus of the midbrain towards target cells in the spinal cord.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1902283	biolink:NamedThing	negative regulation of primary amine oxidase activity	Any process that stops, prevents or reduces the frequency, rate or extent of primary amine oxidase activity.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of amine oxidase (copper-containing) activity|down regulation of amine oxidase (copper-containing) activity|negative regulation of amine oxidase (copper-containing) activity|inhibition of primary-amine:oxygen oxidoreductase (deaminating) activity|downregulation of primary amine oxidase activity|inhibition of primary amine oxidase activity|down-regulation of primary-amine:oxygen oxidoreductase (deaminating) activity|down regulation of primary amine oxidase activity|downregulation of primary-amine:oxygen oxidoreductase (deaminating) activity|down regulation of primary-amine:oxygen oxidoreductase (deaminating) activity|inhibition of amine oxidase (copper-containing) activity|downregulation of amine oxidase (copper-containing) activity|down-regulation of primary amine oxidase activity|negative regulation of primary-amine:oxygen oxidoreductase (deaminating) activity							ecu	2013-07-08T13:27:59Z					biological_process											owl:Class	
GO:0035693	biolink:NamedThing	NOS2-CD74 complex	A protein complex comprising nitric oxide synthase 2 and CD74. This stable complex formation is thought to prevent CD74 degradation by caspases.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-02-25T11:35:38Z					cellular_component											owl:Class	
GO:0010276	biolink:NamedThing	phytol kinase activity	Catalysis of the reaction: phytol + CTP = phytyl monophosphate + CDP + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-7683|EC:2.7.1.182|RHEA:38055									molecular_function											owl:Class	
GO:0042580	biolink:NamedThing	mannosome	A specialised tubular organelle, assembled in hexagonal bundles within an external membrane. Mannosomes are specific to molluscs and are thought to be involved in a general stress reaction.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0004834	biolink:NamedThing	tryptophan synthase activity	Catalysis of the reaction: L-serine + (1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate = L-tryptophan + glyceraldehyde 3-phosphate + H2O.	tmpzr1t_l9r_go_relaxed.owl	L-serine hydro-lyase (adding indoleglycerol-phosphate)|tryptophan synthetase activity|L-tryptophan synthetase activity|L-serine hydro-lyase [adding 1-C-(indol-3-yl)glycerol 3-phosphate; L-tryptophan and glyceraldehyde-3-phosphate-forming]|indoleglycerol phosphate aldolase activity|tryptophan desmolase activity				MetaCyc:TRYPSYN-RXN|RHEA:10532|EC:4.2.1.20|KEGG_REACTION:R02722									molecular_function											owl:Class	
GO:0003122	biolink:NamedThing	norepinephrine-mediated vasodilation	A vasodilation process resulting from secretion of norepinephrine into the bloodstream or released by nerve endings.	tmpzr1t_l9r_go_relaxed.owl	regulation of vasodilation by neuronal noradrenaline|regulation of vasodilation by norepinephrine|regulation of vasodilation by noradrenaline|regulation of vasodilation by circulating noradrenaline|regulation of vasodilation by circulating norepinephrine|regulation of vasodilation by neuronal norepinephrine											GO:0003126|GO:0003125		biological_process											owl:Class	
GO:0052129	biolink:NamedThing	negative energy taxis	The directed movement of a motile cell or organism towards a lower level of a physical stimulus involved in energy generation, such as light, oxygen, and oxidizable substrates.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0030958	biolink:NamedThing	RITS complex	A protein complex required for heterochromatin assembly; contains an Argonaute homolog, a chromodomain protein, and at least one additional protein; named for RNA-induced initiation of transcriptional gene silencing.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0035408	biolink:NamedThing	histone H3-T6 phosphorylation	The modification of histone H3 by the addition of an phosphate group to a threonine residue at position 6 of the histone.	tmpzr1t_l9r_go_relaxed.owl								bf	2010-03-24T10:12:51Z					biological_process											owl:Class	
GO:0090135	biolink:NamedThing	actin filament branching	The formation of daughter actin filament branches at an angle on the sides of preexisting mother filaments.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-12-08T01:53:14Z					biological_process											owl:Class	
GO:0050192	biolink:NamedThing	phosphoglycerate phosphatase activity	Catalysis of the reaction: 2-phospho-D-glycerate + H(2)O = D-glycerate + phosphate.	tmpzr1t_l9r_go_relaxed.owl	glycerophosphate phosphatase activity|D-glycerate-2-phosphate phosphohydrolase activity|D-2-phosphoglycerate phosphatase activity				RHEA:21156|EC:3.1.3.20|MetaCyc:PHOSPHOGLYCERATE-PHOSPHATASE-RXN|KEGG_REACTION:R01748									molecular_function											owl:Class	
GO:0106213	biolink:NamedThing	kinetochore disassembly involved in meiotic chromosome organization	The cell cycle process in which outer kinetochore components delocalize from the centromere, contributing to the rearrangement of chromosomes into the orientation characteristic of meiotic prophase I.	tmpzr1t_l9r_go_relaxed.owl	kinetochore disassembly from spindle pole body involved in chromosome organization involved in meiotic cell cycle							hjd	2019-06-25T18:31:06Z					biological_process											owl:Class	
GO:0006571	biolink:NamedThing	tyrosine biosynthetic process	The chemical reactions and pathways resulting in the formation of tyrosine, an aromatic amino acid, 2-amino-3-(4-hydroxyphenyl)propanoic acid.	tmpzr1t_l9r_go_relaxed.owl	tyrosine biosynthesis|tyrosine synthesis|tyrosine formation|tyrosine anabolism	https://github.com/geneontology/go-ontology/issues/20583												biological_process											owl:Class	
GO:0006605	biolink:NamedThing	protein targeting	The process of targeting specific proteins to particular regions of the cell, typically membrane-bounded subcellular organelles. Usually requires an organelle specific protein sequence motif.	tmpzr1t_l9r_go_relaxed.owl	nascent polypeptide association|protein sorting along secretory pathway				Wikipedia:Protein_targeting	Note that protein targeting encompasses the transport of the protein to the specified location, and may also include additional steps such as protein processing.								biological_process											owl:Class	
GO:0042458	biolink:NamedThing	nopaline catabolic process to proline	The chemical reactions and pathways resulting in the breakdown of nopaline into other compounds, including proline.	tmpzr1t_l9r_go_relaxed.owl	nopaline breakdown to proline|nopaline degradation to proline				MetaCyc:NOPALINEDEG-PWY									biological_process											owl:Class	
GO:0140065	biolink:NamedThing	peptide butyryltransferase activity	Catalysis of the reaction: butyryl-CoA + lysine in peptide = CoA + N-butyryl-lysine-peptide.	tmpzr1t_l9r_go_relaxed.owl	protein butyryltransferase activity							pg	2017-07-20T16:46:49Z					molecular_function											owl:Class	
GO:0048893	biolink:NamedThing	afferent axon development in lateral line nerve	The process whose specific outcome is the progression of an afferent axon in a lateral line nerve over time from its formation to the mature structure. This process includes axonogenesis and pathfinding of the afferent axons in any lateral line nerve.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0051840	biolink:NamedThing	negative regulation by host of cytolysis of symbiont cells	Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of cytolysis by that organism of cells in its symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	down-regulation by host of cytolysis of symbiont cells|downregulation by host of cytolysis of symbiont cells|inhibition by host of cytolysis of symbiont cells|down regulation by host of cytolysis of symbiont cells													biological_process											owl:Class	
GO:0002848	biolink:NamedThing	positive regulation of T cell tolerance induction to tumor cell	Any process that activates or increases the frequency, rate, or extent of T cell tolerance induction to tumor cell.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of T cell tolerance induction to tumor cell|activation of T cell tolerance induction to tumor cell|upregulation of T cell tolerance induction to tumor cell|stimulation of T cell tolerance induction to tumor cell|up regulation of T cell tolerance induction to tumor cell													biological_process											owl:Class	
GO:1901063	biolink:NamedThing	guaiacyl lignin biosynthetic process	The chemical reactions and pathways resulting in the formation of guaiacyl lignin.	tmpzr1t_l9r_go_relaxed.owl	guaiacyl lignin biosynthesis|guaiacyl lignin synthesis|guaiacyl lignin anabolism|G-lignin biosynthetic process|guaiacyl lignin formation							tt	2012-06-29T03:29:53Z					biological_process											owl:Class	
GO:0090474	biolink:NamedThing	arg-arg specific dibasic protein processing	Any protein processing achieved by the cleavage of a peptide bond after two consecutive arginine amino acid residues within a protein.	tmpzr1t_l9r_go_relaxed.owl								tb	2012-10-01T10:42:30Z					biological_process											owl:Class	
GO:0055025	biolink:NamedThing	positive regulation of cardiac muscle tissue development	Any process that activates, maintains or increases the frequency, rate or extent of cardiac muscle tissue development.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of cardiac muscle development|activation of cardiac muscle development|upregulation of cardiac muscle development|up regulation of cardiac muscle development|positive regulation of heart muscle development|stimulation of cardiac muscle development													biological_process											owl:Class	
GO:0043418	biolink:NamedThing	homocysteine catabolic process	The chemical reactions and pathways resulting in the breakdown of homocysteine, the amino acid alpha-amino-gamma-mercaptobutanoic acid.	tmpzr1t_l9r_go_relaxed.owl	homocysteine catabolism|homocysteine degradation|homocysteine breakdown													biological_process											owl:Class	
GO:0061429	biolink:NamedThing	positive regulation of transcription from RNA polymerase II promoter by oleic acid	Any process involving oleic acid that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.	tmpzr1t_l9r_go_relaxed.owl								dph	2012-02-07T09:54:49Z					biological_process											owl:Class	
GO:0052344	biolink:NamedThing	positive regulation by symbiont of host phytoalexin production	Any process in which a symbiont activates, maintains or increases the frequency, rate or extent of the production of phytoalexins as part of the defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	up regulation by symbiont of host phytoalexin production|activation by symbiont of host phytoalexin production|positive regulation by organism of phytoalexin production in other organism involved in symbiotic interaction|stimulation by symbiont of host phytoalexin production|up-regulation by symbiont of host phytoalexin production|upregulation by symbiont of host phytoalexin production											GO:0052329		biological_process											owl:Class	
GO:1902295	biolink:NamedThing	synthesis of RNA primer involved in cell cycle DNA replication	Any DNA replication, synthesis of RNA primer that is involved in cell cycle DNA replication.	tmpzr1t_l9r_go_relaxed.owl	replication priming involved in cell cycle DNA replication|DNA replication, synthesis of RNA primer involved in cell cycle DNA replication							jl	2013-07-09T16:06:26Z					biological_process											owl:Class	
GO:0102591	biolink:NamedThing	delphinidin 7-O-glucoside acyltransferase (acyl-glucose dependent) activity	Catalysis of the reaction: delphinidin 3-O-rutinoside-7-O-glucoside + 1-O-4-hydroxybenzoyl-beta-D-glucose <=> delphinidin 3-O-rutinoside-7-O-(6-O-(p-hydroxybenzoyl)-glucoside) + beta-D-glucose.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-15352									molecular_function											owl:Class	
GO:0019317	biolink:NamedThing	fucose catabolic process	The chemical reactions and pathways resulting in the breakdown of fucose (6-deoxygalactose).	tmpzr1t_l9r_go_relaxed.owl	fucose catabolism|fucose degradation|fucose breakdown				MetaCyc:FUCCAT-PWY									biological_process											owl:Class	
GO:1903056	biolink:NamedThing	regulation of melanosome organization	Any process that modulates the frequency, rate or extent of melanosome organization.	tmpzr1t_l9r_go_relaxed.owl	regulation of melanosome organization and biogenesis|regulation of melanosome organisation					Lack of the transcription factor Zeb2 Q9R0G7 leads to spherical melanosomes with irregular borders, in contrast to the rod-shaped melanosomes of ZEB2MCWT hair follicles		rl	2014-05-27T13:27:49Z					biological_process											owl:Class	
GO:0045058	biolink:NamedThing	T cell selection	The process in which T cells that express T cell receptors that are restricted by self MHC protein complexes and tolerant to self antigens are selected for further maturation.	tmpzr1t_l9r_go_relaxed.owl	T lymphocyte selection|T-cell selection|T-lymphocyte selection				Wikipedia:Thymocyte									biological_process											owl:Class	
GO:0042837	biolink:NamedThing	D-glucarate biosynthetic process	The chemical reactions and pathways resulting in the formation of D-glucarate, the D-enantiomer of glucarate.	tmpzr1t_l9r_go_relaxed.owl	D-glucarate anabolism|D-glucarate formation|saccharate biosynthesis|D-glucarate biosynthesis|saccharate biosynthetic process|D-glucarate synthesis													biological_process											owl:Class	
GO:0019393	biolink:NamedThing	glucarate biosynthetic process	The chemical reactions and pathways resulting in the formation of glucarate, the anion of glucaric acid.	tmpzr1t_l9r_go_relaxed.owl	glucarate anabolism|glucarate formation|glucarate biosynthesis|glucarate synthesis													biological_process											owl:Class	
GO:0010299	biolink:NamedThing	detoxification of cobalt ion	Any process that reduces or removes the toxicity of cobalt ion. These include transport of cobalt away from sensitive areas and to compartments or complexes whose purpose is sequestration of cobalt ion.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0060196	biolink:NamedThing	positive regulation of antisense RNA transcription	Any process that increases the frequency, rate or extent of the synthesis of antisense RNA, an RNA molecule complementary in sequence to another RNA or DNA molecule, which, by binding the latter, acts to inhibit its function and/or completion of synthesis, on a template of DNA.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1990246	biolink:NamedThing	uniplex complex	A calcium channel complex in the mitochondrial inner membrane capable of highly-selective calcium channel activity. Its components include the EF-hand-containing proteins mitochondrial calcium uptake 1 (MICU1) and MICU2, the pore-forming subunit mitochondrial calcium uniporter (MCU) and its paralog MCUb, and the MCU regulator EMRE.	tmpzr1t_l9r_go_relaxed.owl	mitochondrial uniporter complex|mitochondrial uniporter holocomplex							sp	2013-12-04T06:44:35Z					cellular_component											owl:Class	
GO:0034922	biolink:NamedThing	4,5-dihydroxypyrene dioxygenase activity	Catalysis of the reaction: 4,5-dihydroxypyrene + O2 = phenanthrene-4,5-dicarboxylate + 2 H+.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0936|EC:1.13.11.-									molecular_function											owl:Class	
GO:0061973	biolink:NamedThing	membrane bone morphogenesis	The process in which bone which forms deep in the organism are generated and organized.	tmpzr1t_l9r_go_relaxed.owl								dph	2018-02-12T18:21:09Z					biological_process											owl:Class	
GO:2000595	biolink:NamedThing	regulation of optic nerve formation	Any process that modulates the frequency, rate or extent of optic nerve formation.	tmpzr1t_l9r_go_relaxed.owl	regulation of CN II formation|regulation of CN II biosynthesis							yaf	2011-04-11T03:41:30Z					biological_process											owl:Class	
GO:0090564	biolink:NamedThing	protein-phosphocysteine-glucose phosphotransferase system transporter activity	Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein S-phosphocysteine + glucose(out) = protein cysteine + glucose phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.	tmpzr1t_l9r_go_relaxed.owl								tb	2014-04-08T15:03:08Z					molecular_function											owl:Class	
GO:0045631	biolink:NamedThing	regulation of mechanoreceptor differentiation	Any process that modulates the frequency, rate or extent of mechanoreceptor differentiation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0019464	biolink:NamedThing	glycine decarboxylation via glycine cleavage system	The chemical reactions and pathways resulting in the breakdown of glycine by oxidative cleavage to carbon dioxide, ammonia, and a methylene group, mediated by enzymes of the glycine cleavage complex.	tmpzr1t_l9r_go_relaxed.owl	glycine cleavage system				MetaCyc:GLYCLEAV-PWY									biological_process											owl:Class	
GO:0051995	biolink:NamedThing	Se-methyltransferase activity	Catalysis of the transfer of a methyl group to the selenium atom of an acceptor molecule.	tmpzr1t_l9r_go_relaxed.owl								ai	2010-07-16T04:48:08Z					molecular_function											owl:Class	
GO:0071931	biolink:NamedThing	positive regulation of transcription involved in G1/S transition of mitotic cell cycle	Any process that activates or increases transcription as part of the G1/S transition of the mitotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of transcription from RNA polymerase II promoter during G1/S phase of mitotic cell cycle|positive regulation of transcription from RNA polymerase II promoter involved in G1/S transition of mitotic cell cycle							mah	2010-09-29T11:15:34Z					biological_process											owl:Class	
GO:0062097	biolink:NamedThing	chemosynthesis	The cellular metabolic process in which organic chemical compounds are synthesized from carbon-containing molecules and nutrients using energy obtained from the oxidation of inorganic compounds or methane.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Chemosynthesis			dph	2018-11-29T13:18:55Z					biological_process											owl:Class	
GO:0050882	biolink:NamedThing	voluntary musculoskeletal movement	The movement of an organism or part of an organism using mechanoreceptors, the nervous system, striated muscle and/or the skeletal system that can be controlled at will.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0030863	biolink:NamedThing	cortical cytoskeleton	The portion of the cytoskeleton that lies just beneath the plasma membrane.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:1900216	biolink:NamedThing	positive regulation of apoptotic process involved in metanephric collecting duct development	Any process that activates or increases the frequency, rate or extent of apoptotic process involved in metanephric collecting duct development.	tmpzr1t_l9r_go_relaxed.owl	upregulation of programmed cell death by apoptosis of metanephric collecting duct development|upregulation of signaling (initiator) caspase activity of metanephric collecting duct development|up-regulation of apoptosis of metanephric collecting duct development|positive regulation of programmed cell death by apoptosis of metanephric collecting duct development|up-regulation of apoptotic process involved in metanephric collecting duct development|up-regulation of apoptotic programmed cell death of metanephric collecting duct development|upregulation of apoptotic program of metanephric collecting duct development|upregulation of apoptotic process involved in metanephric collecting duct development|positive regulation of apoptotic cell death of metanephric collecting duct development|up regulation of programmed cell death by apoptosis of metanephric collecting duct development|activation of apoptotic programmed cell death of metanephric collecting duct development|activation of apoptotic process of metanephric collecting duct development|up-regulation of type I programmed cell death of metanephric collecting duct development|up regulation of type I programmed cell death of metanephric collecting duct development|upregulation of apoptosis of metanephric collecting duct development|up regulation of apoptotic programmed cell death of metanephric collecting duct development|activation of apoptotic cell death of metanephric collecting duct development|activation of programmed cell death by apoptosis of metanephric collecting duct development|up regulation of apoptotic program of metanephric collecting duct development|activation of type I programmed cell death of metanephric collecting duct development|up-regulation of apoptotic cell death of metanephric collecting duct development|activation of apoptotic program of metanephric collecting duct development|activation of apoptosis of metanephric collecting duct development|up-regulation of apoptotic process of metanephric collecting duct development|positive regulation of apoptotic program of metanephric collecting duct development|up-regulation of apoptotic program of metanephric collecting duct development|up regulation of apoptotic process involved in metanephric collecting duct development|positive regulation of type I programmed cell death of metanephric collecting duct development|up regulation of apoptotic cell death of metanephric collecting duct development|activation of apoptotic process involved in metanephric collecting duct development|up regulation of apoptosis of metanephric collecting duct development|up regulation of signaling (initiator) caspase activity of metanephric collecting duct development|positive regulation of signaling (initiator) caspase activity of metanephric collecting duct development|positive regulation of apoptotic process of metanephric collecting duct development|positive regulation of apoptosis of metanephric collecting duct development|up regulation of apoptotic process of metanephric collecting duct development|upregulation of apoptotic programmed cell death of metanephric collecting duct development|upregulation of apoptotic cell death of metanephric collecting duct development|activation of signaling (initiator) caspase activity of metanephric collecting duct development|up-regulation of programmed cell death by apoptosis of metanephric collecting duct development|upregulation of apoptotic process of metanephric collecting duct development|up-regulation of signaling (initiator) caspase activity of metanephric collecting duct development|positive regulation of apoptotic programmed cell death of metanephric collecting duct development|upregulation of type I programmed cell death of metanephric collecting duct development							yaf	2012-03-22T10:53:39Z					biological_process											owl:Class	
GO:0034836	biolink:NamedThing	6-hydroxy-2-mercaptobenzothiazole monooxygenase activity	Catalysis of the reaction: 6-hydroxy-2-mercaptobenzothiazole + 1/2 O2 = 6,7-dihydroxy-2-mercaptobenzothiazole.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r1181|EC:1.13.12.-									molecular_function											owl:Class	
GO:1902195	biolink:NamedThing	isovaleryl-CoA(4-) metabolic process	The chemical reactions and pathways involving isovaleryl-CoA(4-).	tmpzr1t_l9r_go_relaxed.owl	isovaleryl-CoA(4-) metabolism							ms	2013-06-06T09:55:55Z					biological_process											owl:Class	
GO:0071327	biolink:NamedThing	cellular response to trehalose stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a trehalose stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-12-10T05:27:54Z					biological_process											owl:Class	
GO:0050106	biolink:NamedThing	monomethyl-sulfatase activity	Catalysis of the reaction: H(2)O + monomethyl sulfate = H(+) + methanol + sulfate.	tmpzr1t_l9r_go_relaxed.owl	monomethyl-sulfate sulfohydrolase activity|monomethyl-sulphatase activity				EC:3.1.6.16|MetaCyc:MONOMETHYL-SULFATASE-RXN|RHEA:14221|KEGG_REACTION:R01145									molecular_function											owl:Class	
GO:0048100	biolink:NamedThing	wing disc anterior/posterior pattern formation	The establishment, maintenance and elaboration of the anterior/posterior axis of the wing disc, a precursor to the wing.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0010445	biolink:NamedThing	nuclear dicing body	A small round nuclear body, measuring 0.2-0.8 microns in diameter that is diffusely distributed throughout the nucleoplasm. Several proteins known to be involved in miRNA processing have been localized to these structures. D-bodies are thought to be involved in primary-miRNA processing and/or storage/assembly of miRNA processing complexes.	tmpzr1t_l9r_go_relaxed.owl	D body													cellular_component											owl:Class	
GO:0021788	biolink:NamedThing	chemoattraction of branchiomotor neuron axon in neural tube	The process in which a branchiomotor neuron growth cone in the neural tube is directed to a specific target site in the neural tube in response to an attractive chemical cue. Branchiomotor neurons are located in the hindbrain and innervate branchial arch-derived muscles that control jaw movements, facial expression, the larynx, and the pharynx.	tmpzr1t_l9r_go_relaxed.owl	positive chemotaxis of branchiomotor neuron axon in neural tube													biological_process											owl:Class	
GO:0021786	biolink:NamedThing	branchiomotor neuron axon guidance in neural tube	The process in which a branchiomotor neuron growth cone in the neural tube is directed to a specific target site in the neural tube. Branchiomotor neurons are located in the hindbrain and innervate branchial arch-derived muscles that control jaw movements, facial expression, the larynx, and the pharynx.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0008687	biolink:NamedThing	3,4-dihydroxyphenylacetate 2,3-dioxygenase activity	Catalysis of the reaction: 3,4-dihydroxyphenylacetate + O(2) = 5-formyl-2-hydroxyhepta-2,4-dienedioate + H(+).	tmpzr1t_l9r_go_relaxed.owl	HPC dioxygenase activity|3,4-dihydroxyphenylacetate:oxygen 2,3-oxidoreductase (decyclizing)|3,4-dihydroxyphenylacetic acid 2,3-dioxygenase activity|homoprotocatechuate 2,3-dioxygenase activity				KEGG_REACTION:R03303|EC:1.13.11.15|MetaCyc:1.13.11.15-RXN|UM-BBD_reactionID:r0364|RHEA:15633									molecular_function											owl:Class	
GO:0106164	biolink:NamedThing	positive regulation of exonucleolytic catabolism of deadenylated mRNA	Any process that activates or increases the frequency, rate or extent of exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay.	tmpzr1t_l9r_go_relaxed.owl								hjd	2019-01-15T15:39:19Z					biological_process											owl:Class	
GO:0098665	biolink:NamedThing	serotonin receptor complex	A protein complex that is capable of serotonin receptor activity.	tmpzr1t_l9r_go_relaxed.owl	5-HT receptor complex|5HT receptor complex|5-hydroxytryptamine receptor complex							dos	2016-12-21T12:24:56Z					cellular_component											owl:Class	
GO:1904287	biolink:NamedThing	positive regulation of protein-pyridoxal-5-phosphate linkage	Any process that activates or increases the frequency, rate or extent of protein-pyridoxal-5-phosphate linkage.	tmpzr1t_l9r_go_relaxed.owl	upregulation of protein-pyridoxal-5-phosphate linkage|activation of protein-pyridoxal-5-phosphate linkage|up regulation of protein-pyridoxal-5-phosphate linkage|stimulation of protein-pyridoxal-5-phosphate linkage|up-regulation of protein-pyridoxal-5-phosphate linkage							mcc	2015-06-05T17:21:28Z					biological_process											owl:Class	
GO:0010356	biolink:NamedThing	homogentisate geranylgeranyltransferase activity	Catalysis of the reaction: homogentisic acid + geranylgeranyl diphosphate = 2-methyl-6-geranylgeranylplastoquinol.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0050040	biolink:NamedThing	lactate 2-monooxygenase activity	Catalysis of the reaction: (S)-lactate + O(2) = acetate + CO(2) + H(2)O.	tmpzr1t_l9r_go_relaxed.owl	lactate oxygenase activity|lactate oxidase activity|L-lactate monooxygenase activity|lactic oxygenase activity|lactate oxidative decarboxylase activity|lactate monooxygenase activity|lactic oxidase activity|L-lactate-2-monooxygenase activity|(S)-lactate:oxygen 2-oxidoreductase (decarboxylating)				EC:1.13.12.4|MetaCyc:LACTATE-2-MONOOXYGENASE-RXN|RHEA:16513|KEGG_REACTION:R00319									molecular_function											owl:Class	
GO:0042086	biolink:NamedThing	5-methyl-5,6,7,8-tetrahydromethanopterin-dependent methyltransferase activity	Catalysis of the transfer of a methyl group to an acceptor molecule, dependent on the presence of 5-methyl-5,6,7,8-tetrahydromethanopterin.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0034905	biolink:NamedThing	5-chloro-4-hydroxy-2-oxopentanate aldolase activity	Catalysis of the reaction: 5-chloro-4-hydroxy-2-oxopentanate = pyruvate + chloroacetaldehyde.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r1437|EC:4.1.3.-									molecular_function											owl:Class	
GO:0034467	biolink:NamedThing	esterosome lumen	The volume enclosed by the membrane of an esterosome.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0019300	biolink:NamedThing	rhamnose biosynthetic process	The chemical reactions and pathways resulting in the formation of rhamnose, the hexose 6-deoxy-L-mannose.	tmpzr1t_l9r_go_relaxed.owl	rhamnose formation|rhamnose anabolism|rhamnose biosynthesis|rhamnose synthesis													biological_process											owl:Class	
GO:0140009	biolink:NamedThing	L-aspartate import across plasma membrane	The directed movement of L-aspartate from outside of a cell, across the plasma membrane and into the cytosol.	tmpzr1t_l9r_go_relaxed.owl								pg	2017-03-13T10:59:51Z					biological_process											owl:Class	
GO:1902161	biolink:NamedThing	positive regulation of cyclic nucleotide-gated ion channel activity	Any process that activates or increases the frequency, rate or extent of cyclic nucleotide-gated ion channel activity.	tmpzr1t_l9r_go_relaxed.owl	up regulation of cyclic nucleotide activated ion channel activity|up regulation of cyclic nucleotide-gated ion channel activity|positive regulation of cyclic nucleotide-activated ion channel activity|activation of cyclic nucleotide activated ion channel activity|upregulation of cyclic nucleotide-activated ion channel activity|up-regulation of cyclic nucleotide-activated ion channel activity|positive regulation of cyclic nucleotide activated ion channel activity|upregulation of cyclic nucleotide gated ion channel activity|activation of cyclic nucleotide gated ion channel activity|up regulation of cyclic nucleotide-activated ion channel activity|positive regulation of cyclic nucleotide gated ion channel activity|activation of cyclic nucleotide-activated ion channel activity|up regulation of cyclic nucleotide gated ion channel activity|up-regulation of cyclic nucleotide gated ion channel activity|up-regulation of cyclic nucleotide activated ion channel activity|upregulation of cyclic nucleotide activated ion channel activity|up-regulation of cyclic nucleotide-gated ion channel activity|upregulation of cyclic nucleotide-gated ion channel activity|activation of cyclic nucleotide-gated ion channel activity							sl	2013-05-21T19:24:48Z					biological_process											owl:Class	
GO:0007522	biolink:NamedThing	visceral muscle development	The process whose specific outcome is the progression of the visceral muscle over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0004453	biolink:NamedThing	juvenile-hormone esterase activity	Catalysis of the reaction: methyl (2E,6E)-(10R,11S)-10,11-epoxy-3,7,11-trimethyltrideca-2,6-dienoate + H2O = (2E,6E)-(10R,11S)-10,11-epoxy-3,7,11-trimethyltrideca-2,6-dienoate + methanol. A carboxylesterase that hydrolyzes the ester linkage of juvenile hormone.	tmpzr1t_l9r_go_relaxed.owl	juvenile hormone analog esterase activity|JH-esterase activity|JH esterase activity|juvenile hormone carboxyesterase activity|methyl-(2E,6E)-(10R,11S)-10,11-epoxy-3,7,11-trimethyltrideca-2,6-dienoate acylhydrolase activity				MetaCyc:JUVENILE-HORMONE-ESTERASE-RXN|EC:3.1.1.59|RHEA:16393									molecular_function											owl:Class	
GO:0071298	biolink:NamedThing	cellular response to L-ascorbic acid	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an L-ascorbic acid (vitamin C) stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to L-ascorbate|cellular response to vitamin C|cellular response to ascorbic acid							mah	2009-12-10T04:29:19Z					biological_process											owl:Class	
GO:0071326	biolink:NamedThing	cellular response to monosaccharide stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monosaccharide stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-12-10T05:27:18Z					biological_process											owl:Class	
GO:0047793	biolink:NamedThing	cycloeucalenol cycloisomerase activity	Catalysis of the reaction: cycloeucalenol = obtusifoliol.	tmpzr1t_l9r_go_relaxed.owl	cycloeucalenol lyase (cyclopropane-decyclizing)|cycloeucalenol--obtusifoliol isomerase activity|cycloeucalenol-obtusifoliol isomerase activity				RHEA:22800|EC:5.5.1.9|KEGG_REACTION:R03775|MetaCyc:CYCLOEUCALENOL-CYCLOISOMERASE-RXN									molecular_function											owl:Class	
GO:0016112	biolink:NamedThing	polyterpenoid biosynthetic process	The chemical reactions and pathways resulting in the formation of polyterpenoid compounds, terpenoids with more than eight isoprene units.	tmpzr1t_l9r_go_relaxed.owl	polyterpenoid biosynthesis|polyterpenoid anabolism|polyterpene biosynthesis|polyterpene biosynthetic process|polyterpenoid synthesis|polyterpenoid formation													biological_process											owl:Class	
GO:0016111	biolink:NamedThing	polyterpenoid metabolic process	The chemical reactions and pathways involving polyterpenoid compounds, terpenoids with more than eight isoprene units.	tmpzr1t_l9r_go_relaxed.owl	polyterpenoid metabolism|polyterpene metabolic process|polyterpene metabolism													biological_process											owl:Class	
GO:2000494	biolink:NamedThing	positive regulation of interleukin-18-mediated signaling pathway	Any process that activates or increases the frequency, rate or extent of interleukin-18-mediated signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of interleukin-18-mediated signalling pathway							pr	2011-03-16T02:00:50Z					biological_process											owl:Class	
GO:0102632	biolink:NamedThing	(S)-nandinine synthase activity	Catalysis of the reaction: (S)-scoulerine + [reduced NADPH--hemoprotein reductase] + O2 -> (S)-nandinine + [oxidized NADPH--hemoprotein reductase] + 2 H2O.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/21133			MetaCyc:RXN-15538|RHEA:50364|EC:1.14.19.73									molecular_function											owl:Class	
GO:1902382	biolink:NamedThing	11-oxo-beta-amyrin catabolic process	The chemical reactions and pathways resulting in the breakdown of 11-oxo-beta-amyrin.	tmpzr1t_l9r_go_relaxed.owl	11-oxo-beta-amyrin degradation|11-oxo-beta-amyrin breakdown|11-oxo-beta-amyrin catabolism							ms	2013-09-03T12:55:38Z					biological_process											owl:Class	
GO:0102807	biolink:NamedThing	cyanidin 3-O-glucoside 2''-O-glucosyltransferase activity	Catalysis of the reaction: UDP-alpha-D-glucose + cyanidin 3-O-beta-D-glucoside betaine <=> cyanidin 3-O-sophoroside + UDP + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-8176									molecular_function											owl:Class	
GO:1902458	biolink:NamedThing	positive regulation of stomatal opening	Any process that activates or increases the frequency, rate or extent of stomatal opening.	tmpzr1t_l9r_go_relaxed.owl	upregulation of stomatal opening|activation of stomatal opening|up-regulation of stomatal opening|up regulation of stomatal opening							tb	2013-10-16T22:25:33Z					biological_process											owl:Class	
GO:1902456	biolink:NamedThing	regulation of stomatal opening	Any process that modulates the frequency, rate or extent of stomatal opening.	tmpzr1t_l9r_go_relaxed.owl								tb	2013-10-16T22:25:06Z					biological_process											owl:Class	
GO:0070723	biolink:NamedThing	response to cholesterol	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cholesterol stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-06-15T02:28:27Z					biological_process											owl:Class	
GO:0106233	biolink:NamedThing	glycosome organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a glycosome, a membrane-bounded organelle found in organisms from the order Kinetoplastida that houses the enzymes of glycolysis.	tmpzr1t_l9r_go_relaxed.owl	glycosome biogenesis|glycosome organisation|glycosome organization and biogenesis							hjd	2019-11-01T18:29:46Z					biological_process											owl:Class	
GO:0060329	biolink:NamedThing	cytoplasmic actin-based contraction involved in rearward cell motility	The actin filament-based movement by which cytoplasmic actin filaments slide past one another resulting in a contraction that propels the cell in the direction that has been defined as the rear of the cell.	tmpzr1t_l9r_go_relaxed.owl	cytoplasmic actin-based contraction involved in rearward cell locomotion													biological_process											owl:Class	
GO:0051393	biolink:NamedThing	alpha-actinin binding	Binding to alpha-actinin, one of a family of proteins that cross-link F-actin as antiparallel homodimers. Alpha-actinin has a molecular mass of 93-103 KDa; at the N-terminus there are two calponin homology domains, at the C-terminus there are two EF-hands. These two domains are connected by the rod domain. This domain is formed by triple-helical spectrin repeats.	tmpzr1t_l9r_go_relaxed.owl	alpha-actinin 4 binding|nonmuscle alpha-actinin binding|alpha-actinin 1 binding											GO:0051372		molecular_function											owl:Class	
GO:0042805	biolink:NamedThing	actinin binding	Binding to actinin, any member of a family of proteins that crosslink F-actin.	tmpzr1t_l9r_go_relaxed.owl	beta-actinin binding|capZ binding											GO:0051406		molecular_function											owl:Class	
GO:0033972	biolink:NamedThing	proclavaminate amidinohydrolase activity	Catalysis of the reaction: amidinoproclavaminate + H(2)O = proclavaminate + urea.	tmpzr1t_l9r_go_relaxed.owl	proclavaminate amidino hydrolase activity|PAH|proclavaminic acid amidino hydrolase activity				RHEA:17001|KEGG_REACTION:R05357|MetaCyc:3.5.3.22-RXN|EC:3.5.3.22									molecular_function											owl:Class	
GO:1905922	biolink:NamedThing	negative regulation of acetylcholine biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of acetylcholine biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of acetylcholine formation|downregulation of acetylcholine anabolism|down-regulation of acetylcholine synthesis|inhibition of acetylcholine anabolism|down regulation of acetylcholine biosynthetic process|negative regulation of acetylcholine biosynthesis|negative regulation of acetylcholine formation|downregulation of acetylcholine formation|downregulation of acetylcholine biosynthesis|down regulation of acetylcholine formation|down-regulation of acetylcholine biosynthetic process|inhibition of acetylcholine formation|down-regulation of acetylcholine anabolism|down regulation of acetylcholine anabolism|inhibition of acetylcholine biosynthetic process|negative regulation of acetylcholine anabolism|down regulation of acetylcholine biosynthesis|negative regulation of acetylcholine synthesis|downregulation of acetylcholine biosynthetic process|down regulation of acetylcholine synthesis|downregulation of acetylcholine synthesis|inhibition of acetylcholine biosynthesis|inhibition of acetylcholine synthesis|down-regulation of acetylcholine biosynthesis							bc	2017-02-08T13:08:39Z					biological_process											owl:Class	
GO:0030144	biolink:NamedThing	alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity	Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + N-acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,3(6)-(N-acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl,1,6(3))-beta-D-mannosyl-1,4-N-acetyl-beta-D-glucosaminyl-R = UDP + N-acetyl-beta-D-glucosaminyl-1,2-(N-acetyl-beta-D-glucosaminyl-1,6)-1,2-alpha-D-mannosyl-1,3(6)-(N-acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,6(3))-beta-D-mannosyl-1,4-N-acetyl-beta-D-glucosaminyl-R. Only branched mannose glycopeptides with non-reducing N-acetylglucosamine terminal residues act as acceptors.	tmpzr1t_l9r_go_relaxed.owl	uridine diphosphoacetylglucosamine-alpha-mannoside beta1->6-acetylglucosaminyltransferase activity|GnTV activity|alpha-1,3(6)-mannosylglycoprotein beta-1,6-N-acetylglucosaminyltransferase activity|alpha-mannoside beta-1,6-N-acetylglucosaminyltransferase activity|uridine diphosphoacetylglucosamine-alpha-mannoside beta-1->6-acetylglucosaminyltransferase activity|N-acetylglucosaminyltransferase V activity|UDP-N-acetylglucosamine:alpha-mannoside-beta1,6 N-acetylglucosaminyltransferase activity|alpha-1,6-mannosyl-glycoprotein 6-beta-N-acetylglucosaminyltransferase activity|UDP-N-acetylglucosamine:alpha-mannoside-beta-1,6 N-acetylglucosaminyltransferase activity|UDP-N-acetyl-D-glucosamine:6-[2-(N-acetyl-beta-D-glucosaminyl)-alpha-D-mannosyl]-glycoprotein 6-beta-N-acetyl-D-glucosaminyltransferase activity				Reactome:R-HSA-975916|Reactome:R-HSA-9696980|EC:2.4.1.155|RHEA:16921|MetaCyc:2.4.1.155-RXN									molecular_function											owl:Class	
GO:1903639	biolink:NamedThing	regulation of gastrin-induced gastric acid secretion	Any process that modulates the frequency, rate or extent of gastrin-induced gastric acid secretion.	tmpzr1t_l9r_go_relaxed.owl								sl	2014-11-20T20:54:20Z					biological_process											owl:Class	
GO:0032720	biolink:NamedThing	negative regulation of tumor necrosis factor production	Any process that stops, prevents, or reduces the frequency, rate, or extent of tumor necrosis factor production.	tmpzr1t_l9r_go_relaxed.owl	negative regulation TNF-alpha production|down-regulation of tumor necrosis factor production|down regulation of tumor necrosis factor production|inhibition of tumor necrosis factor production|inhibition of cachectin production|negative regulation tumor necrosis factor-alpha production|negative regulation of tumor necrosis factor secretion|negative regulation of tumor necrosis factor biosynthetic process|downregulation of tumor necrosis factor production|negative regulation TNF production					Note that this term refers only to the specific, original 'tumor necrosis factor' protein (TNF) and not other members of the tumor necrosis factor superfamily (those with the gene symbol root 'TNFSF').		sl	2015-07-09T19:50:08Z			GO:0042536|GO:1904468		biological_process											owl:Class	
GO:0044466	biolink:NamedThing	glutaryl-CoA hydrolase activity	Catalysis of the reaction: glutaryl-CoA + H2O = CoA + glutarate.	tmpzr1t_l9r_go_relaxed.owl	glutaryl-CoA thioesterase activity				EC:3.1.2.3			jl	2012-01-17T04:16:43Z					molecular_function											owl:Class	
GO:0047617	biolink:NamedThing	acyl-CoA hydrolase activity	Catalysis of the reaction: acyl-CoA + H2O = CoA + a carboxylate.	tmpzr1t_l9r_go_relaxed.owl	acyl-CoA thiolesterase activity|acyl coenzyme A hydrolase activity|thioesterase B|acyl-CoA thioesterase II activity|acyl-CoA thioesterase I activity|acyl coenzyme A thioesterase activity|thioesterase II|acyl-CoA thioesterase activity				Reactome:R-HSA-5690066|MetaCyc:ACYL-COA-HYDROLASE-RXN|Reactome:R-HSA-5690042|Reactome:R-HSA-5690043|RHEA:16781|EC:3.1.2.20							GO:0016292|GO:0016291|GO:0008778		molecular_function											owl:Class	
GO:0033425	biolink:NamedThing	CAU codon-amino acid adaptor activity	A triplet codon-amino acid adaptor activity that recognizes a CAU codon.	tmpzr1t_l9r_go_relaxed.owl	histidine tRNA|CAT codon-amino acid adaptor activity					Note that in the standard genetic code, CAT codes for histidine.								molecular_function											owl:Class	
GO:0033821	biolink:NamedThing	DNA beta-glucosyltransferase activity	Catalysis of the transfer of a beta-D-glucosyl residue from UDP-glucose to a hydroxymethylcytosine residue in DNA.	tmpzr1t_l9r_go_relaxed.owl	T4-HMC-beta-glucosyl transferase activity|T4-beta-glucosyl transferase activity|uridine diphosphoglucose-deoxyribonucleate beta-glucosyltransferase activity|UDPglucose:DNA beta-D-glucosyltransferase activity|UDP glucose-DNA beta-glucosyltransferase activity|T4 phage beta-glucosyltransferase activity|UDP-glucose:DNA beta-D-glucosyltransferase activity				MetaCyc:2.4.1.27-RXN|EC:2.4.1.27									molecular_function											owl:Class	
GO:0050447	biolink:NamedThing	zeatin 9-aminocarboxyethyltransferase activity	Catalysis of the reaction: O-acetyl-L-serine + zeatin = L-lupinate + acetate + H(+).	tmpzr1t_l9r_go_relaxed.owl	lupinic acid synthetase activity|lupinic acid synthase activity|beta-(9-cytokinin)-alanine synthase activity|O-acetyl-L-serine acetate-lyase (adding N(6)-substituted adenine) activity|O3-acetyl-L-serine:zeatin 2-amino-2-carboxyethyltransferase activity|beta-(9-cytokinin)alanine synthase activity|3-O-acetyl-L-serine:zeatin 2-amino-2-carboxyethyltransferase activity|O-acetyl-L-serine acetate-lyase (adding N6-substituted adenine)|lupinate synthetase activity				EC:2.5.1.50|RHEA:17333|KEGG_REACTION:R03133|MetaCyc:BETA-9-CYTOKININ-ALANINE-SYNTHASE-RXN									molecular_function											owl:Class	
GO:0098046	biolink:NamedThing	type V protein secretion system complex	A complex of proteins that permits the translocation of proteins across the outer membrane via a transmembrane pore, formed by a beta-barrel, into the extracellular milieu or directly into host cells; the secreted proteins contain all the information required for translocation of an effector molecule through the cell envelope. The type V secretion systems includes the autotransporters (type Va), the two-partner secretion system (type Vb) and the Oca family (type Vc).	tmpzr1t_l9r_go_relaxed.owl	autotransporter system complex|T5SS complex					Note that the type II protein secretion system complex does not include components of the Sec or Tat pathways. For components of these pathways, consider annotating to 'cell envelope Sec complex ; GO:0031522' or 'TAT protein translocation system complex ; GO:0033281'.		bf	2012-08-01T10:05:49Z					cellular_component											owl:Class	
GO:2000865	biolink:NamedThing	negative regulation of estradiol secretion	Any process that stops, prevents or reduces the frequency, rate or extent of estradiol secretion.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of oestradiol secretion							bf	2011-07-26T08:49:17Z					biological_process											owl:Class	
GO:0034724	biolink:NamedThing	DNA replication-independent chromatin organization	The formation or destruction of chromatin structures, occurring outside the context of DNA replication.	tmpzr1t_l9r_go_relaxed.owl	DNA replication-independent nucleosome organisation	https://github.com/geneontology/go-ontology/issues/22130												biological_process											owl:Class	
GO:0030221	biolink:NamedThing	basophil differentiation	The process in which a relatively unspecialized myeloid precursor cell acquires specialized features of a basophil cell.	tmpzr1t_l9r_go_relaxed.owl	basophil cell differentiation													biological_process											owl:Class	
GO:0030851	biolink:NamedThing	granulocyte differentiation	The process in which a myeloid precursor cell acquires the specialized features of a granulocyte. Granulocytes are a class of leukocytes characterized by the presence of granules in their cytoplasm. These cells are active in allergic immune reactions such as arthritic inflammation and rashes. This class includes basophils, eosinophils and neutrophils.	tmpzr1t_l9r_go_relaxed.owl	granulocyte cell differentiation													biological_process											owl:Class	
GO:0099401	biolink:NamedThing	caveola bulb	The region of a caveola that extends into the cytoplasm, excluding the neck (rim).  This region is associated with intracellular caveola proteins.	tmpzr1t_l9r_go_relaxed.owl	caveola crater													cellular_component											owl:Class	
GO:0110055	biolink:NamedThing	negative regulation of actin filament annealing	Any process that stops, prevents or reduces the frequency, rate or extent of actin filament annealing, i.e. the end-to-end joining of existing actin filaments.	tmpzr1t_l9r_go_relaxed.owl								kmv	2017-09-20T20:10:55Z					biological_process											owl:Class	
GO:0110054	biolink:NamedThing	regulation of actin filament annealing	Any process that modulates the frequency, rate or extent of actin filament annealing, i.e. the end-to-end joining of existing actin filaments.	tmpzr1t_l9r_go_relaxed.owl								kmv	2017-09-20T20:07:58Z					biological_process											owl:Class	
GO:1901875	biolink:NamedThing	positive regulation of post-translational protein modification	Any process that activates or increases the frequency, rate or extent of post-translational protein modification.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of post-translational modification|activation of posttranslational modification|upregulation of post-translational protein modification|up-regulation of posttranslational modification|up-regulation of posttranslational amino acid modification|activation of post-translational protein modification|positive regulation of PTM|positive regulation of posttranslational modification|up-regulation of post-translational amino acid modification|activation of post-translational modification|up-regulation of post-translational modification|activation of PTM|positive regulation of post-translational amino acid modification|up-regulation of post-translational protein modification|activation of post-translational amino acid modification|up regulation of posttranslational protein modification|up-regulation of posttranslational protein modification|upregulation of PTM|up regulation of post-translational protein modification|activation of posttranslational protein modification|upregulation of posttranslational modification|up regulation of post-translational modification|positive regulation of posttranslational amino acid modification|up-regulation of PTM|upregulation of post-translational modification|positive regulation of posttranslational protein modification|up regulation of posttranslational modification|up regulation of PTM|up regulation of post-translational amino acid modification|up regulation of posttranslational amino acid modification|upregulation of post-translational amino acid modification|activation of posttranslational amino acid modification|upregulation of posttranslational protein modification|upregulation of posttranslational amino acid modification							yaf	2013-02-05T10:03:02Z					biological_process											owl:Class	
GO:0004162	biolink:NamedThing	dimethylnitrosamine demethylase activity	Catalysis of the removal of a methyl group from N-nitrosodimethylamine.	tmpzr1t_l9r_go_relaxed.owl	N-nitrosodimethylamine demethylase activity													molecular_function											owl:Class	
GO:0060057	biolink:NamedThing	apoptotic process involved in mammary gland involution	Any apoptotic process that triggers the activity of proteolytic caspases whose actions dismantle the mammary epithelial cells resulting in their programmed cell death.	tmpzr1t_l9r_go_relaxed.owl	apoptosis involved in mammary gland involution													biological_process											owl:Class	
GO:1903825	biolink:NamedThing	organic acid transmembrane transport	The process in which an organic acid is transported across a membrane.	tmpzr1t_l9r_go_relaxed.owl								vw	2015-01-20T10:20:58Z					biological_process											owl:Class	
GO:0039677	biolink:NamedThing	exit of virus from host cell nucleus via nuclear envelope disassembly	The directed movement of the viral genome or a viral particle out of the host cell nucleus that involves disruption of the nuclear membrane envelope by the virus.	tmpzr1t_l9r_go_relaxed.owl	exit of virus from host cell nucleus via nuclear envelope breakdown				VZ:2176			bf	2013-09-25T14:10:03Z					biological_process											owl:Class	
GO:1905682	biolink:NamedThing	positive regulation of innate immunity memory response	Any process that activates or increases the frequency, rate or extent of innate immunity memory response.	tmpzr1t_l9r_go_relaxed.owl	activation of innate immunity memory response|up regulation of innate immunity memory response|up-regulation of innate immunity memory response|upregulation of innate immunity memory response							tb	2016-11-11T22:25:36Z					biological_process											owl:Class	
GO:0098865	biolink:NamedThing	modification by symbiont of host bicellular tight junctions	The process in which an organism effects a change in the structure or function of its host bicellular tight junctions, an occluding cell-cell junction that is composed of a branching network of sealing strands that completely encircles the apical end of each cell in an epithelial sheet.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0098864	biolink:NamedThing	modification by symbiont of host tight cell-cell junction	The process in which a symbiont organism effects a change in the structure or function of its host tight junction, a cell-cell junction that seals cells together in an epithelium in a way that prevents even small molecules from leaking from one side of the sheet to the other.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0032641	biolink:NamedThing	lymphotoxin A production	The chemical reactions and pathways resulting in the formation of the cytokine lymphotoxin A.	tmpzr1t_l9r_go_relaxed.owl	TNF-beta production|lymphotoxin A formation|TNF-B production|lymphotoxin-alpha production|lymphotoxin A biosynthetic process|lymphotoxin A synthesis|LTA production|tumor necrosis factor-beta production					Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.						GO:0042109		biological_process											owl:Class	
GO:0010212	biolink:NamedThing	response to ionizing radiation	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ionizing radiation stimulus. Ionizing radiation is radiation with sufficient energy to remove electrons from atoms and may arise from spontaneous decay of unstable isotopes, resulting in alpha and beta particles and gamma rays. Ionizing radiation also includes X-rays.	tmpzr1t_l9r_go_relaxed.owl	response to ionizing radiation stimulus|response to ionising radiation													biological_process											owl:Class	
GO:0097298	biolink:NamedThing	regulation of nucleus size	Any process that modulates the size of the nucleus.	tmpzr1t_l9r_go_relaxed.owl	regulation of nuclear volume|regulation of nuclear size							pr	2012-05-03T06:21:43Z					biological_process											owl:Class	
GO:0008048	biolink:NamedThing	calcium sensitive guanylate cyclase activator activity	Binds to and increases the activity of guanylate cyclase in response to a change in calcium ion concentration.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0000333	biolink:NamedThing	telomerase catalytic core complex	The minimal catalytic core of telomerase is a ribonucleoprotein complex composed of a catalytic reverse transcriptase subunit and an RNA subunit that provides the template for telomeric DNA addition.	tmpzr1t_l9r_go_relaxed.owl	TERT-TERC complex													cellular_component											owl:Class	
GO:0097670	biolink:NamedThing	SCF-Ufo1/Pof10 ubiquitin ligase complex	An SCF ubiquitin ligase complex in which the F-box protein is Ufo1 in S. cerevisiae (Pof10 in S. pombe).	tmpzr1t_l9r_go_relaxed.owl								pr	2014-10-06T10:29:13Z					cellular_component											owl:Class	
GO:1901910	biolink:NamedThing	adenosine 5'-(hexahydrogen pentaphosphate) metabolic process	The chemical reactions and pathways involving adenosine 5'-(hexahydrogen pentaphosphate).	tmpzr1t_l9r_go_relaxed.owl	adenosine 5'-(hexahydrogen pentaphosphate) metabolism							al	2013-02-13T14:17:59Z					biological_process											owl:Class	
GO:0010838	biolink:NamedThing	positive regulation of keratinocyte proliferation	Any process that increases the rate, frequency or extent of keratinocyte proliferation. Keratinocyte proliferation is the multiplication or reproduction of keratinocytes, resulting in the expansion of a cell population.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0098920	biolink:NamedThing	retrograde trans-synaptic signaling by lipid	Cell-cell signaling from postsynapse to presynapse, across the synaptic cleft, mediated by a lipid ligand.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0005865	biolink:NamedThing	striated muscle thin filament	Filaments formed of actin and associated proteins; attached to Z discs at either end of sarcomeres in myofibrils.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0021838	biolink:NamedThing	motogenic signaling involved in interneuron migration from the subpallium to the cortex	The creation and reception of signals that result in the directional movement of interneuron precursors from the subpallium to the cortex.	tmpzr1t_l9r_go_relaxed.owl	motogenic signalling involved in interneuron migration from the subpallium to the cortex													biological_process											owl:Class	
GO:0015946	biolink:NamedThing	methanol oxidation	The chemical reactions and pathways resulting in the conversion of methanol to methyl-Coenzyme M.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:CO2FORM-PWY									biological_process											owl:Class	
GO:0015945	biolink:NamedThing	methanol metabolic process	The chemical reactions and pathways involving methanol, CH3-OH, a colorless, flammable, mobile, poisonous liquid, widely used as a solvent.	tmpzr1t_l9r_go_relaxed.owl	methanol metabolism													biological_process											owl:Class	
GO:0042639	biolink:NamedThing	telogen	The resting phase of hair cycle.	tmpzr1t_l9r_go_relaxed.owl	hair resting phase					Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase. To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).								biological_process											owl:Class	
GO:0070026	biolink:NamedThing	nitric oxide binding	Binding to nitric oxide (NO).	tmpzr1t_l9r_go_relaxed.owl	nitrosyl binding|NO binding|nitrogen monoxide binding													molecular_function											owl:Class	
GO:1990959	biolink:NamedThing	eosinophil homeostasis	The process of regulating the proliferation and elimination of eosinophils such that the total number of eosinophils within a whole or part of an organism is stable over time in the absence of an outside stimulus.	tmpzr1t_l9r_go_relaxed.owl	eosinophilic leukocyte homeostasis|eosinophilic granulocyte homeostasis|eosinocyte homeostasis|eosinophilic leucocyte homeostasis							sl	2016-06-06T22:34:31Z					biological_process											owl:Class	
GO:0015627	biolink:NamedThing	type II protein secretion system complex	A large protein complex, containing 12-15 subunits, that spans the cell envelope of Gram-negative bacteria and mediates the movement of proteins into the extracellular environment. The complex includes a component in the cytoplasm, an inner membrane subcomplex that reaches into the periplasmic compartment and a secretion pore in the outer membrane. Proteins using the Type II pathway are transported across the cytoplasmic membrane by the Sec or Tat complex.	tmpzr1t_l9r_go_relaxed.owl	MTB|T2SS-associated complexes|general secretion pathway-associated complex|Sec-dependent secretion system-associated complex|main terminal branch					Note that the type II protein secretion system complex does not include components of the Sec or Tat pathways. For components of these pathways, consider annotating to 'cell envelope Sec complex ; GO:0031522' or 'TAT protein translocation system complex ; GO:0033281'.								cellular_component											owl:Class	
GO:0102715	biolink:NamedThing	gibberellin A17,oxoglutarate:oxygen oxidoreductase activity	Catalysis of the reaction: gibberellin A17 + 2-oxoglutarate + O2 <=> gibberellin A28 + succinate + carbon dioxide.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-6546									molecular_function											owl:Class	
GO:0015966	biolink:NamedThing	diadenosine tetraphosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of diadenosine tetraphosphate, a derivative of the nucleoside adenosine with four phosphate groups attached.	tmpzr1t_l9r_go_relaxed.owl	diadenosine tetraphosphate biosynthesis|diadenosine tetraphosphate formation|diadenosine tetraphosphate anabolism|diadenosine tetraphosphate synthesis													biological_process											owl:Class	
GO:0018640	biolink:NamedThing	dibenzothiophene monooxygenase activity	Catalysis of the reaction: dibenzothiophene + NADH + H+ + O2 = dibenzothiophene-5-oxide + NAD+ + H2O.	tmpzr1t_l9r_go_relaxed.owl					RHEA:49076|UM-BBD_enzymeID:e0214|MetaCyc:RXN-621									molecular_function											owl:Class	
GO:1990743	biolink:NamedThing	protein sialylation	A protein modification process that results in the addition of a sialic acid unit to the end of an oligosaccharide chain in a glycoprotein.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-05-14T20:18:28Z					biological_process											owl:Class	
GO:0015531	biolink:NamedThing	citrate:proton symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: citrate(out) + H+(out) = citrate(in) + H+(in).	tmpzr1t_l9r_go_relaxed.owl	citrate:hydrogen symporter activity				RHEA:32123									molecular_function											owl:Class	
GO:0070572	biolink:NamedThing	positive regulation of neuron projection regeneration	Any process that activates or increases the frequency, rate or extent of neuron projection regeneration, the regrowth of neuronal processes such as axons or dendrites following their loss or damage.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-04-15T01:45:27Z					biological_process											owl:Class	
GO:0018266	biolink:NamedThing	GPI anchor biosynthetic process via N-aspartyl-glycosylphosphatidylinositolethanolamine	The chemical reactions and pathways resulting in the formation of a C-terminal peptidyl-aspartic acid ethanolamide-linked glycosylphosphatidylinositol (GPI) anchor following hydrolysis of a aspartyl-peptide bond in the carboxy-terminal region of a membrane-associated protein.	tmpzr1t_l9r_go_relaxed.owl	GPI anchor formation via N-aspartyl-glycosylphosphatidylinositolethanolamine|GPI anchor synthesis via N-aspartyl-glycosylphosphatidylinositolethanolamine|GPI anchor anabolism via N-aspartyl-glycosylphosphatidylinositolethanolamine				RESID:AA0159									biological_process											owl:Class	
GO:0018618	biolink:NamedThing	anthranilate 1,2-dioxygenase (deaminating, decarboxylating) activity	Catalysis of the reaction: anthranilate + NADPH + H+ + O2 = catechol + CO2 + NADP+ + NH3.	tmpzr1t_l9r_go_relaxed.owl	anthranilic acid hydroxylase activity|anthranilate dioxygenase reductase|anthranilate dioxygenase activity|anthranilic hydroxylase activity|anthranilate 1,2-dioxygenase|anthranilate hydroxylase activity|AntA|anthranilate,NAD(P)H:oxygen oxidoreductase (1,2-hydroxylating, deaminating, decarboxylating)|AntB|AntC				UM-BBD_reactionID:r0577|EC:1.14.12.1|MetaCyc:1.14.12.1-RXN									molecular_function											owl:Class	
GO:0030298	biolink:NamedThing	receptor signaling protein tyrosine kinase activator activity	Binds to and increases the activity of a receptor signaling protein tyrosine kinase.	tmpzr1t_l9r_go_relaxed.owl	receptor signalling protein tyrosine kinase activator activity													molecular_function											owl:Class	
GO:0031317	biolink:NamedThing	tripartite ATP-independent periplasmic transporter complex	A complex consisting of two membrane proteins and one extracytoplasmic solute receptor. Such transporters transport a variety of substrates without direct ATP power, instead using energy from ion gradients.	tmpzr1t_l9r_go_relaxed.owl	TRAP transporter complex|TRAP-T transporter complex													cellular_component											owl:Class	
GO:0031810	biolink:NamedThing	H4 histamine receptor binding	Binding to a H4 histamine receptor.	tmpzr1t_l9r_go_relaxed.owl	H4 histamine receptor ligand													molecular_function											owl:Class	
GO:1905440	biolink:NamedThing	cellular response to chondroitin 6'-sulfate	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chondroitin 6'-sulfate stimulus.	tmpzr1t_l9r_go_relaxed.owl								cvs	2016-09-14T18:56:19Z					biological_process											owl:Class	
GO:0047319	biolink:NamedThing	aspartate-phenylpyruvate transaminase activity	Catalysis of the reaction: keto-phenylpyruvate + L-aspartate = L-phenylalanine + oxaloacetate.	tmpzr1t_l9r_go_relaxed.owl	aspartate-phenylpyruvate aminotransferase activity|aspartate--phenylpyruvate aminotransferase activity|L-aspartate:phenylpyruvate aminotransferase activity				KEGG_REACTION:R00695|RHEA:14097|EC:2.6.1.70|MetaCyc:2.6.1.70-RXN									molecular_function											owl:Class	
GO:0030887	biolink:NamedThing	positive regulation of myeloid dendritic cell activation	Any process that stimulates, induces or increases the rate of myeloid dendritic cell activation.	tmpzr1t_l9r_go_relaxed.owl	stimulation of myeloid dendritic cell activation|up-regulation of myeloid dendritic cell activation|up regulation of myeloid dendritic cell activation|activation of myeloid dendritic cell activation|upregulation of myeloid dendritic cell activation													biological_process											owl:Class	
GO:0030885	biolink:NamedThing	regulation of myeloid dendritic cell activation	Any process that modulates the frequency or rate of myeloid dendritic cell activation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0047098	biolink:NamedThing	Latia-luciferin monooxygenase (demethylating) activity	Catalysis of the reaction: 2 O2 + donor-H2 + Latia luciferin = light + H2O + acceptor + formate + CO2 + oxidized Latia luciferin.	tmpzr1t_l9r_go_relaxed.owl	Latia luciferin monooxygenase (demethylating)|luciferase (Latia luciferin)|Latia-luciferin,hydrogen-donor:oxygen oxidoreductase (demethylating)				RHEA:12677|MetaCyc:1.14.99.21-RXN|EC:1.14.99.21									molecular_function											owl:Class	
GO:0033636	biolink:NamedThing	modulation by symbiont of host response to temperature stimulus	Any process in which an organism modulates a change in state or activity of a host cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a temperature stimulus. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	modulation by symbiont of host response to thermal stimulus													biological_process											owl:Class	
GO:0031537	biolink:NamedThing	regulation of anthocyanin metabolic process	Any process that modulates the frequency, rate or extent of chemical reactions and pathways involving anthocyanins.	tmpzr1t_l9r_go_relaxed.owl	regulation of anthocyanin metabolism													biological_process											owl:Class	
GO:0006728	biolink:NamedThing	pteridine biosynthetic process	The chemical reactions and pathways resulting in the formation of pteridine, pyrazino(2,3-dipyrimidine), the parent structure of pterins and the pteroyl group.	tmpzr1t_l9r_go_relaxed.owl	pterin biosynthesis|pterin biosynthetic process|pteridine formation|pteridine anabolism|pteridine biosynthesis|pteridine synthesis													biological_process											owl:Class	
GO:0043004	biolink:NamedThing	cytoplasmic sequestering of CFTR protein	The selective interaction of Cystic Fibrosis Transmembrane conductance Regulator (CFTR) protein with specific molecules in the cytoplasm, thereby inhibiting its transport to the cell membrane.	tmpzr1t_l9r_go_relaxed.owl	retention of CFTR (cystic fibrosis transmembrane conductance regulator) protein in cytoplasm|sequestration of CFTR (cystic fibrosis transmembrane conductance regulator protein) in cytoplasm|sequestering of CFTR (cystic fibrosis transmembrane conductance regulator protein) in cytoplasm|cytoplasmic sequestration of CFTR (cystic fibrosis transmembrane conductance regulator protein)|cytoplasmic retention of CFTR (cystic fibrosis transmembrane conductance regulator) protein|storage of CFTR (cystic fibrosis transmembrane conductance regulator) protein in cytoplasm|maintenance of CFTR protein location in cytoplasm|cytoplasmic storage of CFTR (cystic fibrosis transmembrane conductance regulator) protein|cytoplasmic sequestering of cystic fibrosis transmembrane conductance regulator protein													biological_process											owl:Class	
GO:0051220	biolink:NamedThing	cytoplasmic sequestering of protein	The selective interaction of a protein with specific molecules in the cytoplasm, thereby inhibiting its transport into other areas of the cell.	tmpzr1t_l9r_go_relaxed.owl	retention of protein in cytoplasm|cytoplasmic sequestration of protein|sequestering of protein in cytoplasm|sequestration of protein in cytoplasm|cytoplasmic storage of protein|cytoplasmic retention of protein|storage of protein in cytoplasm|maintenance of protein location in cytoplasm													biological_process											owl:Class	
GO:1904853	biolink:NamedThing	protein localization to ascospore wall	A process in which a protein is transported to, or maintained in, a location within an ascospore wall.	tmpzr1t_l9r_go_relaxed.owl	protein localisation to ascospore wall|protein localization in ascospore wall|protein localisation in ascospore wall							mah	2015-12-14T12:52:50Z					biological_process											owl:Class	
GO:0030706	biolink:NamedThing	germarium-derived oocyte differentiation	The process in which one relatively unspecialized immature cystocyte of the germ-line cyst in the germarium acquires the specialized features of an oocyte. An example of this process can be found in Drosophila melanogaster.	tmpzr1t_l9r_go_relaxed.owl	oocyte cell differentiation													biological_process											owl:Class	
GO:0035454	biolink:NamedThing	extrinsic component of stromal side of plastid inner membrane	The component of a plastid inner membrane consisting of gene products and protein complexes that are loosely bound to its stromal surface, but not integrated into the hydrophobic region.	tmpzr1t_l9r_go_relaxed.owl	extrinsic to stromal leaflet of plastid inner membrane|extrinsic to stromal side of plastid inner membrane|peripheral to stromal side of plastid inner membrane							bf	2010-04-16T10:23:12Z					cellular_component											owl:Class	
GO:0018908	biolink:NamedThing	organosulfide cycle	A cyclic series of interconversions involving dimethyl sulfide, methanethiol and hydrogen sulfide. Dimethylsulfoxide can also be converted to dimethyl sulfide, which enters the cycle.	tmpzr1t_l9r_go_relaxed.owl	organosulphide cycle				UM-BBD_pathwayID:sulf									biological_process											owl:Class	
GO:0007132	biolink:NamedThing	meiotic metaphase I	The cell cycle phase, following prophase I, during which chromosomes become aligned on the equatorial plate of the cell as part of meiosis I.	tmpzr1t_l9r_go_relaxed.owl						Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).								biological_process											owl:Class	
GO:0071408	biolink:NamedThing	cellular response to cycloalkane	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cycloalkane stimulus. A cycloalkane is a cyclic saturated hydrocarbon having the general formula CnH2n.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-12-14T02:57:15Z					biological_process											owl:Class	
GO:0106240	biolink:NamedThing	labd-13Z-ene-9,15,16-triol synthase activity	Catalysis of the reaction:O2 + peregrinol + reduced [NADPH--hemoprotein reductase] = H(+) + H2O + labd-13Z-ene-9,15,16-triol + oxidized [NADPH--hemoprotein reductase].	tmpzr1t_l9r_go_relaxed.owl					RHEA:62192			hjd	2019-12-19T17:43:00Z					molecular_function											owl:Class	
GO:0038203	biolink:NamedThing	TORC2 signaling	A series of intracellular molecular signals mediated by TORC2; TOR (rapamycin-insensitive companion of TOR) in complex with at least Rictor (regulatory-associated protein of TOR), or orthologs of, and other signaling components.	tmpzr1t_l9r_go_relaxed.owl	TORC2 signal transduction							bf	2013-12-09T14:43:29Z					biological_process											owl:Class	
GO:1990393	biolink:NamedThing	3M complex	A protein complex, at least composed of CUL7, CCDC8 and OBSL1, that is required for maintaining microtubule and genome integrity.	tmpzr1t_l9r_go_relaxed.owl								sp	2014-06-05T06:40:49Z					cellular_component											owl:Class	
GO:0033775	biolink:NamedThing	deoxysarpagine hydroxylase activity	Catalysis of the reaction: 10-deoxysarpagine + H(+) + NADPH + O(2) = H(2)O + NADP(+) + sarpagine.	tmpzr1t_l9r_go_relaxed.owl	DOSH|10-deoxysarpagine,NADPH:oxygen oxidoreductase (10-hydroxylating) activity				KEGG_REACTION:R05828|EC:1.14.14.136|MetaCyc:1.14.13.91-RXN|RHEA:14237									molecular_function											owl:Class	
GO:0097269	biolink:NamedThing	all-trans-decaprenyl-diphosphate synthase activity	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate + 7 isopentenyl diphosphate = 7 diphosphate + all-trans-decaprenyl diphosphate.	tmpzr1t_l9r_go_relaxed.owl	(2E,6E)-farnesyl-diphosphate:isopentenyl-diphosphate farnesyltranstransferase activity|2-trans,6-trans-farnesyl diphosphate activity				RHEA:27802|EC:2.5.1.91|Reactome:R-HSA-2162253			pr	2012-03-20T01:00:23Z					molecular_function											owl:Class	
GO:0102866	biolink:NamedThing	di-homo-gamma-linolenate delta5 desaturase activity	Catalysis of the reaction: all-cis-icosa-8,11,14-trienoate + O2 + a reduced electron acceptor <=> arachidonate + 2 H2O + an oxidized electron acceptor.	tmpzr1t_l9r_go_relaxed.owl					RHEA:46260|MetaCyc:RXN-8346									molecular_function											owl:Class	
GO:0051549	biolink:NamedThing	positive regulation of keratinocyte migration	Any process that activates or increases the frequency, rate or extent of keratinocyte migration.	tmpzr1t_l9r_go_relaxed.owl	activation of keratinocyte migration|up-regulation of keratinocyte migration|up regulation of keratinocyte migration|upregulation of keratinocyte migration|stimulation of keratinocyte migration													biological_process											owl:Class	
GO:0000483	biolink:NamedThing	endonucleolytic cleavage of tetracistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, 2S rRNA, LSU-rRNA)	Endonucleolytic cleavage of a pre-rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small SubUnit (SSU) rRNA, the 5.8S rRNA, 2S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript. Primary ribosomal RNA transcripts with four genes, in this order, are produced in the nuclei of D. melanogaster as well as in those of other dipteran species.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0090601	biolink:NamedThing	enucleation	The process in which nucleated precursor cells lose their nucleus.	tmpzr1t_l9r_go_relaxed.owl								tb	2014-09-05T16:25:16Z					biological_process											owl:Class	
GO:0061322	biolink:NamedThing	disseminated nephrocyte differentiation	The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a disseminated nephrocyte. A disseminated nephrocyte is an insect renal cell that filters hemolymph and is found at scattered locations in the fat body or other tissues. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-09-24T12:30:46Z					biological_process											owl:Class	
GO:0061319	biolink:NamedThing	nephrocyte differentiation	The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a nephrocyte. A nephrocyte is an insect renal cell that filters hemolymph. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-09-24T12:23:29Z					biological_process											owl:Class	
GO:1900594	biolink:NamedThing	(+)-kotanin metabolic process	The chemical reactions and pathways involving (+)-kotanin.	tmpzr1t_l9r_go_relaxed.owl	(+)-kotanin metabolism							di	2012-05-15T06:54:19Z					biological_process											owl:Class	
GO:0050822	biolink:NamedThing	peptide stabilization	Any process involved in maintaining the structure and integrity of a peptide and preventing it from being degraded.	tmpzr1t_l9r_go_relaxed.owl	peptide stabilisation|peptide stabilization activity													biological_process											owl:Class	
GO:0031529	biolink:NamedThing	ruffle organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a ruffle, a projection at the leading edge of a crawling cell.	tmpzr1t_l9r_go_relaxed.owl	ruffle organisation|ruffle organization and biogenesis													biological_process											owl:Class	
GO:0071497	biolink:NamedThing	cellular response to freezing	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a freezing stimulus, temperatures below 0 degrees Celsius.	tmpzr1t_l9r_go_relaxed.owl	ice nucleation inhibitor activity|antifreeze activity							mah	2009-12-18T02:41:02Z					biological_process											owl:Class	
GO:0050826	biolink:NamedThing	response to freezing	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a freezing stimulus, temperatures below 0 degrees Celsius.	tmpzr1t_l9r_go_relaxed.owl	ice nucleation inhibitor activity|antifreeze activity													biological_process											owl:Class	
GO:0071346	biolink:NamedThing	cellular response to interferon-gamma	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-gamma stimulus. Interferon gamma is the only member of the type II interferon found so far.	tmpzr1t_l9r_go_relaxed.owl	cellular response to type II interferon|cellular response to gamma-interferon|cellular response to type II IFN|cellular response to immune interferon							mah	2009-12-11T02:48:00Z					biological_process											owl:Class	
GO:0019129	biolink:NamedThing	peptidyl-leucine racemization	The racemization of peptidyl-leucine.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0197							GO:0018093|GO:0018375		biological_process											owl:Class	
GO:0051026	biolink:NamedThing	chiasma assembly	The cell cycle process in which a connection between chromatids assembles, indicating where an exchange of homologous segments has taken place by the crossing-over of non-sister chromatids.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0047773	biolink:NamedThing	carnitinamidase activity	Catalysis of the reaction: (R)-carnitinamide + H(2)O = (R)-carnitine + NH(4)(+).	tmpzr1t_l9r_go_relaxed.owl	L-carnitine amidase activity|L-carnitinamidase activity|L-carnitinamide amidohydrolase activity|carnitine amidase activity				MetaCyc:CARNITINAMIDASE-RXN|EC:3.5.1.73|RHEA:17537|KEGG_REACTION:R01922									molecular_function											owl:Class	
GO:0008760	biolink:NamedThing	UDP-N-acetylglucosamine 1-carboxyvinyltransferase activity	Catalysis of the reaction: phosphoenolpyruvate + UDP-N-acetyl-alpha-D-glucosamine = phosphate + UDP-N-acetyl-3-O-(1-carboxyvinyl)-D-glucosamine.	tmpzr1t_l9r_go_relaxed.owl	pyruvate-uridine diphospho-N-acetylglucosamine transferase activity|phosphoenolpyruvate:UDP-2-acetamido-2-deoxy-D-glucose 2-enoyl-1-carboxyethyltransferase activity|pyruvic-uridine diphospho-N-acetylglucosaminyltransferase activity|phosphoenolpyruvate-UDP-acetylglucosamine-3-enolpyruvyltransferase activity|MurA transferase activity|enoylpyruvate transferase activity|pyruvate-uridine diphospho-N-acetyl-glucosamine transferase activity|UDP-N-acetylglucosamine 1-carboxyvinyl-transferase activity|UDP-N-acetylglucosamine enoylpyruvyltransferase activity|phosphoenolpyruvate:uridine-5'-diphospho-N-acetyl-2-amino-2-deoxyglucose 3-enolpyruvyltransferase activity|phosphopyruvate-uridine diphosphoacetylglucosamine pyruvatetransferase activity|phosphoenolpyruvate:UDP-N-acetyl-D-glucosamine 1-carboxyvinyltransferase activity|phosphoenolpyruvate:uridine diphosphate N-acetylglucosamine enolpyruvyltransferase activity|pyruvate-UDP-acetylglucosamine transferase activity				EC:2.5.1.7|RHEA:18681|KEGG_REACTION:R00660|MetaCyc:UDPNACETYLGLUCOSAMENOLPYRTRANS-RXN									molecular_function											owl:Class	
GO:0046298	biolink:NamedThing	2,4-dichlorobenzoate catabolic process	The chemical reactions and pathways resulting in the breakdown of 2,4-dichlorobenzoate, a chlorinated aromatic compound which is a key intermediate in the aerobic degradation of polychlorinated biphenyls (PCBs).	tmpzr1t_l9r_go_relaxed.owl	2,4-dichlorobenzoate breakdown|2,4-dichlorobenzoate catabolism|2,4-dichlorobenzoate degradation													biological_process											owl:Class	
GO:0046047	biolink:NamedThing	TTP catabolic process	The chemical reactions and pathways resulting in the breakdown of TTP, ribosylthymine triphosphate.	tmpzr1t_l9r_go_relaxed.owl	TTP breakdown|TTP degradation|TTP catabolism|TTP hydrolysis													biological_process											owl:Class	
GO:0047530	biolink:NamedThing	2,4-diaminopentanoate dehydrogenase activity	Catalysis of the reaction: 2,4-diaminopentanoate + H2O + NAD(P)+ = 2-amino-4-oxopentanoate + NH3 + NAD(P)H + H+.	tmpzr1t_l9r_go_relaxed.owl	2,4-diaminopentanoic acid C4 dehydrogenase activity|2,4-diaminopentanoate:NAD(P)+ oxidoreductase (deaminating)				EC:1.4.1.12|MetaCyc:24-DIAMINOPENTANOATE-DEHYDROGENASE-RXN									molecular_function											owl:Class	
GO:0010398	biolink:NamedThing	xylogalacturonan metabolic process	The chemical reactions and pathways involving xylogalacturonan, a pectin characterized by a backbone of alpha-(1->4)-linked D-galacturonic acid residues substituted on C-3 with beta-D-xylopyranose residues.	tmpzr1t_l9r_go_relaxed.owl	xylogalacturonan metabolism													biological_process											owl:Class	
GO:0047308	biolink:NamedThing	alanine-oxomalonate transaminase activity	Catalysis of the reaction: L-alanine + oxomalonate = aminomalonate + pyruvate.	tmpzr1t_l9r_go_relaxed.owl	alanine--oxomalonate aminotransferase activity|L-alanine:oxomalonate aminotransferase activity|alanine-ketomalonate (mesoxalate) transaminase activity|L-alanine-ketomalonate transaminase activity|alanine-oxomalonate aminotransferase activity				RHEA:18809|KEGG_REACTION:R02970|EC:2.6.1.47|MetaCyc:2.6.1.47-RXN									molecular_function											owl:Class	
GO:0006477	biolink:NamedThing	protein sulfation	The addition of a sulfate group as an ester to a protein amino acid.	tmpzr1t_l9r_go_relaxed.owl	protein amino acid sulphation|protein amino acid sulfation													biological_process											owl:Class	
GO:0032812	biolink:NamedThing	positive regulation of epinephrine secretion	Any process that activates or increases the frequency, rate or extent of the regulated release of epinephrine.	tmpzr1t_l9r_go_relaxed.owl	stimulation of epinephrine secretion|upregulation of epinephrine secretion|activation of epinephrine secretion|up-regulation of epinephrine secretion|up regulation of epinephrine secretion|positive regulation of adrenaline secretion													biological_process											owl:Class	
GO:0047982	biolink:NamedThing	homocysteine desulfhydrase activity	Catalysis of the reaction: L-homocysteine + H2O = sulfide + NH3 + 2-oxobutanoate.	tmpzr1t_l9r_go_relaxed.owl	L-homocysteine hydrogen-sulfide-lyase (deaminating; 2-oxobutanoate-forming)|homocysteine desulfurase activity|L-homocysteine hydrogen-sulfide-lyase (deaminating)				EC:4.4.1.2|Reactome:R-HSA-1614631|MetaCyc:HOMOCYSTEINE-DESULFHYDRASE-RXN|RHEA:14501									molecular_function											owl:Class	
GO:0047095	biolink:NamedThing	2-hydroxycyclohexanone 2-monooxygenase activity	Catalysis of the reaction: 2-hydroxycyclohexan-1-one + NADPH + O(2) = 6-oxohexanoate + H(2)O + NADP(+).	tmpzr1t_l9r_go_relaxed.owl	2-hydroxycyclohexan-1-one,NADPH:oxygen 2-oxidoreductase (1,2-lactonizing)				RHEA:33283|MetaCyc:1.14.13.66-RXN|EC:1.14.13.66|KEGG_REACTION:R03281									molecular_function											owl:Class	
GO:0048630	biolink:NamedThing	skeletal muscle tissue growth	The increase in size or mass of a skeletal muscle. This may be due to a change in the fiber number or size.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1900535	biolink:NamedThing	palmitic acid biosynthetic process	The chemical reactions and pathways resulting in the formation of palmitic acid.	tmpzr1t_l9r_go_relaxed.owl								tb	2012-05-09T07:05:17Z					biological_process											owl:Class	
GO:0061159	biolink:NamedThing	establishment of bipolar cell polarity involved in cell morphogenesis	The specification and formation of bipolar intracellular organization or cell growth patterns that contribute to cell morphogenesis. Bipolar organization is the organization that is a mirror image along an axis from a plane.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-06-23T09:14:39Z					biological_process											owl:Class	
GO:0090701	biolink:NamedThing	specification of plant organ identity	The regionalization process in which the identity of a plant organ primordium is specified. Identity is considered to be the aggregate of characteristics by which a structure is recognized.	tmpzr1t_l9r_go_relaxed.owl								tb	2016-08-29T15:09:18Z					biological_process											owl:Class	
GO:0035759	biolink:NamedThing	mesangial cell-matrix adhesion	The binding of a mesangial cell to the extracellular matrix via adhesion molecules. A mesangial cell is a cell that encapsulates the capillaries and venules in the kidney.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-03-25T02:06:21Z					biological_process											owl:Class	
GO:0046665	biolink:NamedThing	amnioserosa maintenance	Maintenance of the amnioserosa, an epithelium that occupies a hole in the embryonic dorsal epidermis.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1904657	biolink:NamedThing	negative regulation of sensory perception of sweet taste	Any process that stops, prevents or reduces the frequency, rate or extent of sensory perception of sweet taste.	tmpzr1t_l9r_go_relaxed.owl	inhibition of sensory perception of sweet taste|negative regulation of sweet taste perception|downregulation of sweet taste perception|down regulation of sensory perception of sweet taste|down regulation of sweet taste perception|down-regulation of sweet taste perception|down-regulation of sensory perception of sweet taste|downregulation of sensory perception of sweet taste|inhibition of sweet taste perception							mr	2015-09-04T16:43:18Z					biological_process											owl:Class	
GO:0048307	biolink:NamedThing	ferredoxin-nitrite reductase activity	Catalysis of the reaction: NH3 + 2 H2O + 6 oxidized ferredoxin = nitrite + 6 reduced ferredoxin + 7 H+.	tmpzr1t_l9r_go_relaxed.owl	ammonia:ferredoxin oxidoreductase activity				RHEA:18041|MetaCyc:FERREDOXIN--NITRITE-REDUCTASE-RXN|EC:1.7.7.1									molecular_function											owl:Class	
GO:0018469	biolink:NamedThing	myrtenal dehydrogenase activity	Catalysis of the reaction: myrtenal + H2O = 2 H+ + 2 e- + myrtenic acid.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0711									molecular_function											owl:Class	
GO:0099081	biolink:NamedThing	supramolecular polymer	A polymeric supramolecular structure.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0071861	biolink:NamedThing	tachykinin receptor binding	Binding to a tachykinin receptor.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-09-10T03:24:34Z					molecular_function											owl:Class	
GO:1904465	biolink:NamedThing	negative regulation of matrix metallopeptidase secretion	Any process that stops, prevents or reduces the frequency, rate or extent of matrix metallopeptidase secretion.	tmpzr1t_l9r_go_relaxed.owl	down regulation of MMP secretion|inhibition of matrix metallopeptidase secretion|down-regulation of matrix metalloproteinase secretion|down regulation of matrix metalloproteinase secretion|downregulation of MMP secretion|inhibition of matrix metalloproteinase secretion|down-regulation of matrix metallopeptidase secretion|down regulation of matrix metallopeptidase secretion|down-regulation of MMP secretion|negative regulation of matrix metalloproteinase secretion|negative regulation of MMP secretion|downregulation of matrix metallopeptidase secretion|downregulation of matrix metalloproteinase secretion|inhibition of MMP secretion							sl	2015-07-09T19:46:24Z					biological_process											owl:Class	
GO:0070564	biolink:NamedThing	positive regulation of vitamin D receptor signaling pathway	Any process that activates or increases the frequency, rate or extent of vitamin D receptor signaling pathway activity.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of vitamin D receptor signaling pathway|up regulation of vitamin D receptor signaling pathway|activation of vitamin D receptor signaling pathway|upregulation of vitamin D receptor signaling pathway|positive regulation of vitamin D receptor signalling pathway|positive regulation of VDR signaling pathway|stimulation of vitamin D receptor signaling pathway							mah	2009-04-14T02:02:54Z					biological_process											owl:Class	
GO:0097303	biolink:NamedThing	lipoprotein biosynthetic process via N-acyl transfer	The chemical reactions and pathways by which N-acyl transfer leads to formation of a water-soluble protein-lipid complex.	tmpzr1t_l9r_go_relaxed.owl	lipoprotein biosynthesis (N-acyl transfer)							pr	2012-05-15T01:03:59Z					biological_process											owl:Class	
GO:0036380	biolink:NamedThing	UDP-N-acetylglucosamine-undecaprenyl-phosphate N-acetylglucosaminephosphotransferase activity	Catalysis of the reaction: UDP-N-acetyl-alpha-D-glucosamine + ditrans,octacis-undecaprenyl phosphate = UMP + N-acetyl-alpha-D-glucosaminyldiphospho-ditrans,octacis-undecaprenol.	tmpzr1t_l9r_go_relaxed.owl	UDP-N-acetylglucosamine:undecaprenyl-phosphate GlcNAc-1-phosphate transferase activity|UDP-N-acetyl-D-glucosamine:ditrans,octacis-undecaprenyl phosphate N-acetyl-D-glucosaminephosphotransferase activity|UDP-GIcNAc:undecaprenyl phosphate N-acetylglucosaminyl 1-P transferase activity|UDP-GlcNAc:undecaprenyl-phosphate GlcNAc-1-phosphate transferase activity|GlcNAc-P-P-Und synthase activity				MetaCyc:GLCNACPTRANS-RXN|KEGG_REACTION:R08856|EC:2.7.8.33|RHEA:28090			bf	2013-05-23T10:51:26Z					molecular_function											owl:Class	
GO:1904123	biolink:NamedThing	positive regulation of fatty acid beta-oxidation by serotonin receptor signaling pathway	A serotonin receptor signaling pathway that results in positive regulation of fatty acid beta-oxidation.	tmpzr1t_l9r_go_relaxed.owl	activation of fatty acid beta-oxidation by serotonin receptor signaling pathway|up-regulation of fatty acid beta-oxidation by serotonin receptor signaling pathway|stimulation of fatty acid beta-oxidation by serotonin receptor signaling pathway|upregulation of fatty acid beta-oxidation by serotonin receptor signaling pathway|up regulation of fatty acid beta-oxidation by serotonin receptor signaling pathway							kmv	2015-04-08T21:03:20Z					biological_process											owl:Class	
GO:0097310	biolink:NamedThing	cap2 mRNA methylation	Methylation of the ribose of the first and second nucleotides of a 5'-capped mRNA.	tmpzr1t_l9r_go_relaxed.owl	cap2 mRNA capping							pr	2012-05-23T04:05:07Z					biological_process											owl:Class	
GO:0031782	biolink:NamedThing	type 4 melanocortin receptor binding	Binding to a type 4 melanocortin receptor.	tmpzr1t_l9r_go_relaxed.owl	type 4 melanocortin receptor ligand													molecular_function											owl:Class	
GO:0001784	biolink:NamedThing	phosphotyrosine residue binding	Binding to a phosphorylated tyrosine residue within a protein.	tmpzr1t_l9r_go_relaxed.owl	phosphotyrosine binding													molecular_function											owl:Class	
GO:0003201	biolink:NamedThing	epithelial to mesenchymal transition involved in coronary vasculature morphogenesis	A transition where a cardiac epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell that will contribute to the shaping of the coronary vasculature.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-10-08T01:36:54Z					biological_process											owl:Class	
GO:0051030	biolink:NamedThing	snRNA transport	The directed movement of snRNA, small nuclear ribonucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0033755	biolink:NamedThing	sulfur oxygenase/reductase activity	Catalysis of the reaction: 4 sulfur + 4 H2O + O2 = 2 hydrogen sulfide + 2 bisulfite + 2 H+.	tmpzr1t_l9r_go_relaxed.owl	sulfur:oxygen oxidoreductase (hydrogen-sulfide- and sulfite-forming) activity|SOR|sulfur oxygenase activity|sulphur oxygenase/reductase activity				MetaCyc:1.13.11.55-RXN|EC:1.13.11.55|RHEA:13957									molecular_function											owl:Class	
GO:0070907	biolink:NamedThing	histidine:histamine antiporter activity	Catalysis of the reaction: histidine(out) + histamine(in) = histidine(in) + histamine(out).	tmpzr1t_l9r_go_relaxed.owl	histidine/histamine antiporter activity|histidine-histamine antiporter activity							mah	2009-09-04T03:47:07Z					molecular_function											owl:Class	
GO:0035615	biolink:NamedThing	clathrin adaptor activity	Bringing together a cargo protein with clathrin, responsible for the formation of endocytic vesicles.	tmpzr1t_l9r_go_relaxed.owl	clathrin-associated adaptor activity							bf	2010-12-01T11:17:57Z					molecular_function											owl:Class	
GO:0140312	biolink:NamedThing	cargo adaptor activity	Binding directly to the structural scaffolding elements of a vesicle coat (such as clathrin or COPII), and bridging the membrane, cargo receptor, and membrane deformation machinery.	tmpzr1t_l9r_go_relaxed.owl	endocytic adaptor activity	https://github.com/geneontology/go-ontology/issues/19454|https://github.com/geneontology/go-ontology/issues/17553						pg	2019-03-26T17:01:45Z			GO:0098748		molecular_function											owl:Class	
GO:0034949	biolink:NamedThing	1,1-dichloroethane reductive dehalogenase activity	Catalysis of the reaction: 1,1-dichloroethane + 2 H+ + 2 e- = chloroethane + HCl.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r1008|EC:1.97.1.-									molecular_function											owl:Class	
GO:0071878	biolink:NamedThing	negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway	Any process that stops, prevents, or reduces the frequency, rate or extent of an adenylate cyclase-activating adrenergic receptor protein signaling pathway activity. An adrenergic receptor signaling pathway is the series of molecular signals generated as a consequence of an adrenergic receptor binding to one of its physiological ligands.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of adrenergic receptor signalling pathway|negative regulation of adrenergic receptor signaling pathway							mah	2010-09-13T04:15:34Z					biological_process											owl:Class	
GO:0043876	biolink:NamedThing	D-threonine aldolase activity	Catalysis of the reaction: D-threonine (or D-allo-threonine) = glycine + acetaldehyde.	tmpzr1t_l9r_go_relaxed.owl	low-specificity D-threonine aldolase|D-allo-threonine aldolase activity|D-TA|D-allo-TA|DtaAS				EC:4.1.2.42|RHEA:15257|MetaCyc:4.1.2.42-RXN									molecular_function											owl:Class	
GO:0097267	biolink:NamedThing	omega-hydroxylase P450 pathway	The chemical reactions and pathways by which arachidonic acid is converted to other compounds initially by omega-hydroxylation.	tmpzr1t_l9r_go_relaxed.owl	P450 omega-hydroxylase pathway							pr	2012-03-15T12:58:15Z					biological_process											owl:Class	
GO:0001587	biolink:NamedThing	Gq/11-coupled serotonin receptor activity	Combining with serotonin and transmitting the signal across the membrane by activation of the Gq/11 subunit of an associated cytoplasmic heterotrimeric G protein complex. The Gq/11 subunit subsequently activates phospholipase C and results in an increase in inositol triphosphate (IP3) levels.	tmpzr1t_l9r_go_relaxed.owl	5-HT2 receptor activity|serotonin receptor activity, coupled via Gq/11													molecular_function											owl:Class	
GO:0072226	biolink:NamedThing	metanephric long descending thin limb bend development	The process whose specific outcome is the progression of the metanephric long descending thin limb bend over time, from its formation to the mature structure. The metanephric long descending thin limb bend is a part of the descending thin limb of a long nephron that lies beyond the prebend segment in the metanephros.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-03-18T03:37:16Z					biological_process											owl:Class	
GO:0072005	biolink:NamedThing	maintenance of kidney identity	The process in which the identity of a kidney is maintained. Identity is considered to be the aggregate of characteristics by which a structure is recognized.	tmpzr1t_l9r_go_relaxed.owl	maintenance of kidney anlage identity							mah	2010-01-25T11:57:41Z					biological_process											owl:Class	
GO:0016615	biolink:NamedThing	malate dehydrogenase activity	Catalysis of the reversible conversion of pyruvate or oxaloacetate to malate.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1990551	biolink:NamedThing	mitochondrial 2-oxoadipate transmembrane transport	The process in which 2-oxoadipate is transported across a mitochondrial membrane, into or out of the mitochondrion.	tmpzr1t_l9r_go_relaxed.owl								vw	2014-11-19T12:25:48Z					biological_process											owl:Class	
GO:0098747	biolink:NamedThing	slow, calcium ion-dependent exocytosis of neurotransmitter	The slow, second phase of calcium ion-induced neurotransmitter release, via exocytosis, into the synaptic cleft. This depends on high affinity calcium sensors and decays slowly, typically with a decay constant of over 100ms. The underlying molecular mechanisms of this process are distinct from those of the earlier, fast phase of release.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0070434	biolink:NamedThing	positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway	Any process that activates or increases the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing 2 (NOD2) pathway.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of nucleotide-binding oligomerization domain containing 2 signalling pathway|positive regulation of NOD2 signaling pathway													biological_process											owl:Class	
GO:0018990	biolink:NamedThing	ecdysis, chitin-based cuticle	The shedding of the old chitin-based cuticlar fragments during the molting cycle. An example of this is found in Drosophila melanogaster.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0150069	biolink:NamedThing	negative regulation of tubulin deacetylase activity	Any process that stops, prevents or reduces the frequency, rate or extent of tubulin deacetylase activity.	tmpzr1t_l9r_go_relaxed.owl								bc	2018-07-24T10:40:19Z					biological_process											owl:Class	
GO:0047497	biolink:NamedThing	mitochondrion transport along microtubule	The directed movement of a mitochondrion along a microtubule, mediated by motor proteins.	tmpzr1t_l9r_go_relaxed.owl	mitochondrial migration along microtubule|mitochondrial transport along microtubule													biological_process											owl:Class	
GO:1990433	biolink:NamedThing	CSL-Notch-Mastermind transcription factor complex	A DNA-binding transcription factor complex consisting of CSL and mastermind proteins in complex with the cleaved, intracellular domain of Notch. It is required for both repression and activation of Notch target genes.	tmpzr1t_l9r_go_relaxed.owl	CSL-NotchIC-MASTERMIND complex							bhm	2014-07-30T14:41:43Z					cellular_component											owl:Class	
GO:0008941	biolink:NamedThing	nitric oxide dioxygenase activity	Catalysis of the reaction: 2 NO + 2 O2 + NADPH + H+ = 2 nitrate + NADP+.	tmpzr1t_l9r_go_relaxed.owl	nitric oxide,NAD(P)H:oxygen oxidoreductase activity|NOD activity				MetaCyc:R621-RXN|Reactome:R-HSA-5340226|Reactome:R-HSA-1222723|EC:1.14.12.17									molecular_function											owl:Class	
GO:1904543	biolink:NamedThing	negative regulation of free ubiquitin chain polymerization	Any process that stops, prevents or reduces the frequency, rate or extent of free ubiquitin chain polymerization.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of free ubiquitin chain polymerization|downregulation of free ubiquitin chain polymerization|inhibition of free ubiquitin chain polymerization|down regulation of free ubiquitin chain polymerization					An example of this is PARK2 in human (UniProt symbol O60260) in PMID:24660806 (inferred from mutant phenotype).		pad	2015-08-11T11:45:00Z					biological_process											owl:Class	
GO:1903349	biolink:NamedThing	omegasome membrane	Any membrane that is part of an omegasome.	tmpzr1t_l9r_go_relaxed.owl								pr	2014-08-19T12:33:09Z					cellular_component											owl:Class	
GO:0061733	biolink:NamedThing	peptide-lysine-N-acetyltransferase activity	Catalysis of the reaction: acetyl-CoA + lysine in peptide = CoA + N-acetyl-lysine-peptide.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-6811508|Reactome:R-HSA-8951966|Reactome:R-HSA-9626945|Reactome:R-HSA-9617758|Reactome:R-HSA-9620515			dph	2015-09-10T10:22:19Z					molecular_function											owl:Class	
GO:0003785	biolink:NamedThing	actin monomer binding	Binding to monomeric actin, also known as G-actin.	tmpzr1t_l9r_go_relaxed.owl	G actin binding													molecular_function											owl:Class	
GO:0062077	biolink:NamedThing	phenylacetyl-CoA 1,2-epoxidase complex	A protein complex capable of catalysing the reaction: phenylacetyl-CoA + H(+) + NADPH + O2 = 2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA + H2O + NADP(+).	tmpzr1t_l9r_go_relaxed.owl	paaABCE complex							dph	2018-09-27T12:40:04Z					cellular_component											owl:Class	
GO:0071476	biolink:NamedThing	cellular hypotonic response	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a hypotonic environment, i.e. an environment with a lower concentration of solutes than the organism or cell.	tmpzr1t_l9r_go_relaxed.owl	cellular hypo-osmotic response							mah	2009-12-18T11:52:59Z					biological_process											owl:Class	
GO:0042935	biolink:NamedThing	achromobactin transport	The directed movement of achromobactin, a citrate siderophore, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0032423	biolink:NamedThing	regulation of mismatch repair	Any process that modulates the frequency, rate or extent of mismatch repair.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0046638	biolink:NamedThing	positive regulation of alpha-beta T cell differentiation	Any process that activates or increases the frequency, rate or extent of alpha-beta T cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	upregulation of alpha-beta T cell differentiation|positive regulation of alpha-beta T cell development|up regulation of alpha-beta T cell differentiation|positive regulation of alpha-beta T lymphocyte differentiation|up-regulation of alpha-beta T cell differentiation|positive regulation of alpha-beta T-lymphocyte differentiation|activation of alpha-beta T cell differentiation|positive regulation of alpha-beta T-cell differentiation|stimulation of alpha-beta T cell differentiation					Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.								biological_process											owl:Class	
GO:0002400	biolink:NamedThing	tolerance induction in nasopharyngeal-associated lymphoid tissue	Tolerance induction taking place in the nasopharyngeal-associated lymphoid tissue (NALT).	tmpzr1t_l9r_go_relaxed.owl	nasal tolerance|tolerance induction in NALT													biological_process											owl:Class	
GO:0018272	biolink:NamedThing	protein-pyridoxal-5-phosphate linkage via peptidyl-N6-pyridoxal phosphate-L-lysine	The modification of peptidyl-lysine to form N6-pyridoxal phosphate-L-lysine.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0119									biological_process											owl:Class	
GO:0033816	biolink:NamedThing	diaminobutyrate acetyltransferase activity	Catalysis of the reaction: L-2,4-diaminobutyrate + acetyl-CoA = N(4)-acetyl-L-2,4-diaminobutyrate + CoA + H(+).	tmpzr1t_l9r_go_relaxed.owl	2,4-diaminobutanoate acetyltransferase activity|DABAcT|acetyl-CoA:L-2,4-diaminobutanoate 4-N-acetyltransferase activity|diaminobutyric acid acetyltransferase activity|acetyl-CoA:L-2,4-diaminobutanoate N4-acetyltransferase activity|L-2,4-diaminobutyrate acetyltransferase activity|DABA acetyltransferase activity|L-2,4-diaminobutanoate acetyltransferase activity|DAB acetyltransferase activity|EctA				KEGG_REACTION:R06978|RHEA:16901|MetaCyc:R102-RXN|EC:2.3.1.178									molecular_function											owl:Class	
GO:1902877	biolink:NamedThing	positive regulation of embryonic pattern specification	Any process that activates or increases the frequency, rate or extent of embryonic pattern specification.	tmpzr1t_l9r_go_relaxed.owl	upregulation of embryonic pattern specification|positive regulation of ventral/lateral system|activation of ventral/lateral system|activation of embryonic pattern specification|up regulation of embryonic pattern specification|up-regulation of ventral/lateral system|up regulation of ventral/lateral system|upregulation of ventral/lateral system|up-regulation of embryonic pattern specification							mr	2014-04-03T15:25:26Z					biological_process											owl:Class	
GO:0018862	biolink:NamedThing	phenylphosphate carboxylase activity	Catalysis of the reaction: phenylphosphate + CO2 + H2O = H+ + phosphate + 4-hydroxybenzoate.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:PHENYLPCARB-RXN|EC:6.4.1.-|UM-BBD_reactionID:r0157									molecular_function											owl:Class	
GO:0098619	biolink:NamedThing	selenocysteine-tRNA ligase activity	Catalysis of the reaction: tRNASec + L-Ser + ATP = Ser-tRNASec + AMP + diphosphate.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-2408526									molecular_function											owl:Class	
GO:1903807	biolink:NamedThing	L-threonine import across plasma membrane	The directed movement of L-threonine from outside of a cell, across the plasma membrane and into the cytosol.	tmpzr1t_l9r_go_relaxed.owl	L-threonine uptake|L-threonine import into cell|L-threonine import							bf	2012-05-11T10:46:21Z			GO:0036231		biological_process											owl:Class	
GO:0048408	biolink:NamedThing	epidermal growth factor binding	Binding to epidermal growth factor.	tmpzr1t_l9r_go_relaxed.owl	EGF binding													molecular_function											owl:Class	
GO:0033953	biolink:NamedThing	alpha-agarase activity	Catalysis of the endohydrolysis of 1,3-alpha-L-galactosidic linkages in agarose, yielding agarotetraose as the major product.	tmpzr1t_l9r_go_relaxed.owl	agarose 3-glycanohydrolase activity|agarase A33 activity|agarase activity				MetaCyc:3.2.1.158-RXN|EC:3.2.1.158									molecular_function											owl:Class	
GO:0038017	biolink:NamedThing	Wnt receptor internalization	A receptor-mediated endocytosis process that results in the movement of a Wnt receptor from the plasma membrane to the inside of the cell.	tmpzr1t_l9r_go_relaxed.owl	Wnt receptor endocytosis							bf	2011-06-23T04:25:47Z					biological_process											owl:Class	
GO:0015411	biolink:NamedThing	ABC-type taurine transporter transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + taurine(out) = ADP + phosphate + taurine(in).	tmpzr1t_l9r_go_relaxed.owl	ATPase-coupled taurine transporter activity|taurine-transporting ATPase activity|taurine ABC transporter|ATP-dependent taurine transporter activity	https://github.com/geneontology/go-ontology/issues/21640			EC:7.6.2.7|MetaCyc:ABC-64-RXN|RHEA:14613|MetaCyc:3.6.3.36-RXN									molecular_function											owl:Class	
GO:0030505	biolink:NamedThing	inorganic diphosphate transport	The directed movement of inorganic diphosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	inorganic pyrophosphate transport													biological_process											owl:Class	
GO:0008118	biolink:NamedThing	N-acetyllactosaminide alpha-2,3-sialyltransferase activity	Catalysis of the reaction: CMP-N-acetylneuraminate + beta-D-galactosyl-1,4-N-acetyl-D-glucosaminyl-glycoprotein = CMP + alpha-N-acetylneuraminyl-2,3-beta-D-galactosyl-1,4-N-acetyl-D-glucosaminyl-glycoprotein.	tmpzr1t_l9r_go_relaxed.owl	SiaT|cytidine monophosphoacetylneuraminate-beta-galactosyl(1->4)acetylglucosaminide alpha2->3-sialyltransferase activity|CMP-N-acetylneuraminate:beta-D-galactosyl-1,4-N-acetyl-D-glucosaminyl-glycoprotein alpha-2,3-N-acetylneuraminyltransferase activity|alpha2->3 sialyltransferase activity				MetaCyc:2.4.99.6-RXN|EC:2.4.99.6|RHEA:52316									molecular_function											owl:Class	
GO:0031693	biolink:NamedThing	alpha-1D adrenergic receptor binding	Binding to an alpha-1D adrenergic receptor.	tmpzr1t_l9r_go_relaxed.owl	alpha-1D adrenergic receptor ligand													molecular_function											owl:Class	
GO:0004615	biolink:NamedThing	phosphomannomutase activity	Catalysis of the reaction: alpha-D-mannose 1-phosphate = D-mannose 6-phosphate.	tmpzr1t_l9r_go_relaxed.owl	phosphomannose mutase activity|alpha-D-mannose 1,6-phosphomutase activity|D-mannose 1,6-phosphomutase activity|mannose phosphomutase activity				KEGG_REACTION:R01818|Reactome:R-HSA-446201|MetaCyc:PHOSMANMUT-RXN|Reactome:R-HSA-3781926|EC:5.4.2.8|RHEA:11140							GO:0008971		molecular_function											owl:Class	
GO:0044482	biolink:NamedThing	envenomation resulting in blood vessel extracellular matrix damage, causing hemorrhagic damage in other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism which causes damage to the extracellular matrix of the blood vessels of the bitten organism, ultimately resulting in hemorrhage in the bitten organism.	tmpzr1t_l9r_go_relaxed.owl	envenomation resulting in blood vessel ECM, causing hemorrhagic damage in other organism							jl	2012-01-19T03:12:04Z					biological_process											owl:Class	
GO:0036239	biolink:NamedThing	taxoid 7beta-hydroxylase activity	Catalysis of the reaction: taxusin + O2 + NADPH + H+ = 7beta-hydroxytaxusin + NADP+ + H2O.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-12885|KEGG_REACTION:R09868|EC:1.14.13.147|RHEA:31975			bf	2012-05-22T02:13:21Z					molecular_function											owl:Class	
GO:0006669	biolink:NamedThing	sphinganine-1-phosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of sphinganine-1-phosphate, the phosphorylated derivative of D-erythro-2-amino-1,3-octadecanediol.	tmpzr1t_l9r_go_relaxed.owl	sphinganine-1-phosphate synthesis|sphinganine-1-phosphate biosynthesis|sphinganine-1-phosphate anabolism|sphinganine-1-phosphate formation|dihydrosphingosine-1-phosphate biosynthetic process|dihydrosphingosine-1-phosphate biosynthesis													biological_process											owl:Class	
GO:0003846	biolink:NamedThing	2-acylglycerol O-acyltransferase activity	Catalysis of the reaction: acyl-CoA + 2-acylglycerol = CoA + diacylglycerol.	tmpzr1t_l9r_go_relaxed.owl	acylglycerol palmitoyltransferase activity|acyl coenzyme A-monoglyceride acyltransferase activity|acyl-CoA:2-acylglycerol O-acyltransferase activity|monoacylglycerol acyltransferase activity|monoglyceride acyltransferase activity				Reactome:R-HSA-5696448|EC:2.3.1.22|RHEA:16741|Reactome:R-HSA-6800334|MetaCyc:2-ACYLGLYCEROL-O-ACYLTRANSFERASE-RXN									molecular_function											owl:Class	
GO:0010040	biolink:NamedThing	response to iron(II) ion	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iron(II) ion stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to iron(II)													biological_process											owl:Class	
GO:0060615	biolink:NamedThing	mammary gland bud formation	The morphogenetic process in which a bud forms from the mammary placode. A mammary bud is bulb of epithelial cells that is distinct from the surrounding epidermis.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-05-18T08:43:14Z					biological_process											owl:Class	
GO:0038057	biolink:NamedThing	TNFSF11 binding	Binding to tumor necrosis factor ligand superfamily member 11 (TNFSF11), a member of the tumor necrosis factor (TNF) cytokine family.	tmpzr1t_l9r_go_relaxed.owl	tumor necrosis factor ligand superfamily member 11 binding|osteoclast differentiation factor binding|RANKL binding|TRANCE binding|CD254 binding|receptor activator of nuclear factor kappa-B ligand binding|osteoprotegerin ligand binding|tumor necrosis factor (ligand) superfamily member 11 binding|tumor necrosis factor superfamily member 11 binding|TNF-related activation-induced cytokine binding|OPGL binding|ODF binding							bf	2012-01-04T03:25:59Z					molecular_function											owl:Class	
GO:0043120	biolink:NamedThing	tumor necrosis factor binding	Binding to tumor necrosis factor, a proinflammatory cytokine produced by monocytes and macrophages.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1903945	biolink:NamedThing	positive regulation of hepatocyte apoptotic process	Any process that activates or increases the frequency, rate or extent of hepatocyte apoptotic process.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of hepatocyte apoptosis|upregulation of hepatocyte apoptotic process|up regulation of hepatocyte apoptosis|upregulation of hepatocyte apoptosis|up regulation of hepatocyte apoptotic process|activation of hepatocyte apoptosis|up-regulation of hepatocyte apoptotic process|activation of hepatocyte apoptotic process|positive regulation of hepatocyte apoptosis							sl	2015-02-19T12:54:59Z					biological_process											owl:Class	
GO:0061792	biolink:NamedThing	secretory granule maturation	Steps required to transform an immature secretory vesicle into a mature secretory vesicle. Typically proceeds through homotypic membrane fusion and membrane remodelling.	tmpzr1t_l9r_go_relaxed.owl								dph	2016-09-09T13:24:34Z					biological_process											owl:Class	
GO:1990482	biolink:NamedThing	sphingolipid alpha-glucuronosyltransferase activity	Catalysis of the reaction: UDP-glucuronate + inositol phosphorylceramide (IPC) = UDP + GlcA-IPC.	tmpzr1t_l9r_go_relaxed.owl	inositol phosphorylceramide glucuronosyltransferase activity							tb	2014-09-12T22:10:09Z					molecular_function											owl:Class	
GO:0099525	biolink:NamedThing	presynaptic dense core vesicle exocytosis	The secretion of molecules (e.g. neuropeptides and neuromodulators such as serotonin and dopamine) contained within a membrane-bounced dense in response to increased presynaptic cytosolic calcium levels.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0005641	biolink:NamedThing	nuclear envelope lumen	The region between the two lipid bilayers of the nuclear envelope; 20-40 nm wide.	tmpzr1t_l9r_go_relaxed.owl	nuclear membrane lumen|perinuclear space|nuclear intermembrane space					Note that this term should not be confused with the cellular component term 'perinuclear region ; GO:0048471'.						GO:0005653		cellular_component											owl:Class	
GO:0090619	biolink:NamedThing	meiotic spindle pole	Either of the ends of a meiotic spindle, a spindle that forms as part of meiosis, where spindle microtubules are organized; usually contains a microtubule organizing center and accessory molecules, spindle microtubules and astral microtubules.	tmpzr1t_l9r_go_relaxed.owl								tb	2014-12-16T16:38:34Z					cellular_component											owl:Class	
GO:0007023	biolink:NamedThing	post-chaperonin tubulin folding pathway	Completion of folding of alpha- and beta-tubulin; takes place subsequent to chaperonin-mediated partial folding; mediated by a complex of folding cofactors.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1900084	biolink:NamedThing	regulation of peptidyl-tyrosine autophosphorylation	Any process that modulates the frequency, rate or extent of peptidyl-tyrosine autophosphorylation.	tmpzr1t_l9r_go_relaxed.owl	regulation of receptor tyrosine kinase autophosphorylation|regulation of tyrosine autophosphorylation							bf	2012-02-03T10:17:07Z					biological_process											owl:Class	
GO:0046038	biolink:NamedThing	GMP catabolic process	The chemical reactions and pathways resulting in the breakdown of GMP, guanosine monophosphate.	tmpzr1t_l9r_go_relaxed.owl	GMP degradation|GMP breakdown|GMP catabolism													biological_process											owl:Class	
GO:0044565	biolink:NamedThing	dendritic cell proliferation	The expansion of a dendritic cell population by cell division. A dendritic cell is a cell of hematopoietic origin, typically resident in particular tissues, specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-04-05T04:31:39Z					biological_process											owl:Class	
GO:0004082	biolink:NamedThing	bisphosphoglycerate mutase activity	Catalysis of the reaction: 3-phospho-D-glyceroyl phosphate = 2,3-bisphospho-D-glycerate.	tmpzr1t_l9r_go_relaxed.owl	diphosphoglyceromutase activity|2,3-bisphosphoglycerate synthase activity|2,3-bisphosphoglycerate mutase activity|diphosphoglyceric mutase activity|2,3-diphosphoglycerate mutase activity|diphosphoglycerate mutase activity|biphosphoglycerate synthase activity|2,3-diphosphoglyceromutase activity|bisphosphoglyceromutase|DPGM|glycerate phosphomutase activity|3-phospho-D-glycerate 1,2-phosphomutase activity|BPGM activity|bisphosphoglycerate synthase activity|2,3-diphosphoglycerate synthase activity				EC:5.4.2.4|MetaCyc:BISPHOSPHOGLYCERATE-MUTASE-RXN|RHEA:17765|Reactome:R-HSA-6798335									molecular_function											owl:Class	
GO:0070274	biolink:NamedThing	RES complex	A protein complex that is required for efficient splicing, and prevents leakage of unspliced pre-mRNAs from the nucleus (named for pre-mRNA REtention and Splicing). In Saccharomyces, the complex consists of Ist3p, Bud13p, and Pml1p.	tmpzr1t_l9r_go_relaxed.owl	pre-mRNA retention and splicing complex													cellular_component											owl:Class	
GO:0150100	biolink:NamedThing	RNA binding involved in posttranscriptional gene silencing	Any RNA binding that is involved in posttranscriptional gene silencing.	tmpzr1t_l9r_go_relaxed.owl	RNA binding involved in PTGS|RNA binding involved in cosuppression|RNA binding involved in quelling|RNA binding involved in post-transcriptional gene silencing							bc	2019-03-11T11:48:27Z					molecular_function											owl:Class	
GO:0032912	biolink:NamedThing	negative regulation of transforming growth factor beta2 production	Any process that stops, prevents, or reduces the frequency, rate, or extent of production of transforming growth factor-beta2.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of TGFB2 production|downregulation of transforming growth factor-beta2 production|down-regulation of transforming growth factor-beta2 production|down regulation of transforming growth factor-beta2 production|inhibition of transforming growth factor-beta2 production|negative regulation of transforming growth factor-beta2 production|negative regulation of TGF-B2 production													biological_process											owl:Class	
GO:0005833	biolink:NamedThing	hemoglobin complex	An iron-containing, oxygen carrying complex. In vertebrates it is made up of two pairs of associated globin polypeptide chains, each chain carrying a noncovalently bound heme prosthetic group.	tmpzr1t_l9r_go_relaxed.owl	haemoglobin complex													cellular_component											owl:Class	
GO:0003868	biolink:NamedThing	4-hydroxyphenylpyruvate dioxygenase activity	Catalysis of the reaction: 4-hydroxyphenylpyruvate + O2 = homogentisate + CO2.	tmpzr1t_l9r_go_relaxed.owl	p-hydroxyphenylpyruvic acid hydroxylase activity|p-hydroxyphenylpyruvic oxidase activity|p-hydroxyphenylpyruvate oxidase activity|4-hydroxyphenylpyruvate:oxygen oxidoreductase (hydroxylating, decarboxylating)|p-hydroxyphenylpyruvic hydroxylase activity|p-hydroxyphenylpyruvate dioxygenase activity|4-hydroxyphenylpyruvic acid dioxygenase activity|4-hydroxyphenylpyruvate hydroxylase activity|p-hydroxyphenylpyruvate hydroxylase activity				UM-BBD_reactionID:r0298|Reactome:R-HSA-71163|EC:1.13.11.27|RHEA:16189|MetaCyc:4-HYDROXYPHENYLPYRUVATE-DIOXYGENASE-RXN									molecular_function											owl:Class	
GO:0045973	biolink:NamedThing	positive regulation of juvenile hormone secretion	Any process that activates or increases the frequency, rate or extent of the regulated release of juvenile hormone.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of juvenile hormone secretion|up regulation of juvenile hormone secretion|activation of juvenile hormone secretion|stimulation of juvenile hormone secretion|upregulation of juvenile hormone secretion													biological_process											owl:Class	
GO:1903552	biolink:NamedThing	negative regulation of extracellular exosome assembly	Any process that stops, prevents or reduces the frequency, rate or extent of extracellular vesicular exosome assembly.	tmpzr1t_l9r_go_relaxed.owl	inhibition of extracellular vesicular exosome assembly|downregulation of extracellular vesicular exosome assembly|down-regulation of extracellular vesicular exosome assembly|down regulation of extracellular vesicular exosome assembly|negative regulation of extracellular vesicular exosome assembly							pga	2014-10-20T15:37:33Z					biological_process											owl:Class	
GO:0034579	biolink:NamedThing	(1-methylpentyl)succinate synthase activity	Catalysis of the reaction: fumarate + n-hexane = (1-methylpentyl)succinate.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0920									molecular_function											owl:Class	
GO:0010200	biolink:NamedThing	response to chitin	A process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chitin stimulus.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0031920	biolink:NamedThing	pyridoxal transport	The directed movement of pyridoxal into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Pyridoxal, 3-hydroxy-5-(hydroxymethyl)-2-methyl-4-pyridinecarboxaldehyde, is one of the vitamin B6 compounds. Pyridoxal, pyridoxamine and pyridoxine are collectively known as vitamin B6, and are efficiently converted to the biologically active form of vitamin B6, pyridoxal phosphate.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1904197	biolink:NamedThing	positive regulation of granulosa cell proliferation	Any process that activates or increases the frequency, rate or extent of granulosa cell proliferation.	tmpzr1t_l9r_go_relaxed.owl	upregulation of granulosa cell proliferation|up-regulation of granulosa cell proliferation|up regulation of granulosa cell proliferation|activation of granulosa cell proliferation							sl	2015-05-07T17:02:40Z					biological_process											owl:Class	
GO:1903815	biolink:NamedThing	negative regulation of collecting lymphatic vessel constriction	Any process that stops, prevents or reduces the frequency, rate or extent of collecting lymphatic vessel constriction.	tmpzr1t_l9r_go_relaxed.owl	downregulation of lymphatic vessel myogenic constriction|negative regulation of lymphatic vessel myogenic constriction|downregulation of collecting lymphatic vessel constriction|inhibition of collecting lymphatic vessel constriction|down-regulation of collecting lymphatic vessel constriction|inhibition of lymphatic vessel myogenic constriction|down-regulation of lymphatic vessel myogenic constriction|down regulation of collecting lymphatic vessel constriction|down regulation of lymphatic vessel myogenic constriction							sl	2015-01-16T17:01:58Z					biological_process											owl:Class	
GO:2001107	biolink:NamedThing	negative regulation of Rho guanyl-nucleotide exchange factor activity	Any process that stops, prevents or reduces the frequency, rate or extent of Rho guanyl-nucleotide exchange factor activity.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of RhoGEF|negative regulation of Rho guanine nucleotide exchange factor							yaf	2011-09-23T10:13:12Z					biological_process											owl:Class	
GO:1901914	biolink:NamedThing	negative regulation of capsule organization	Any process that stops, prevents or reduces the frequency, rate or extent of capsule organization.	tmpzr1t_l9r_go_relaxed.owl	downregulation of capsule organisation|inhibition of capsule organization|down-regulation of capsule organization|down regulation of capsule organization and biogenesis|down regulation of capsule organization|downregulation of capsule organization and biogenesis|negative regulation of capsule organisation|negative regulation of capsule organization and biogenesis|down regulation of capsule organisation|down-regulation of capsule organization and biogenesis|inhibition of capsule organisation|downregulation of capsule organization|down-regulation of capsule organisation|inhibition of capsule organization and biogenesis							di	2013-02-14T06:19:07Z					biological_process											owl:Class	
GO:1905295	biolink:NamedThing	regulation of neural crest cell fate specification	Any process that modulates the frequency, rate or extent of neural crest cell fate specification.	tmpzr1t_l9r_go_relaxed.owl								rl	2016-06-28T15:14:40Z					biological_process											owl:Class	
GO:1904323	biolink:NamedThing	regulation of inhibitory G protein-coupled receptor phosphorylation	Any process that modulates the frequency, rate or extent of inhibitory G protein-coupled receptor phosphorylation.	tmpzr1t_l9r_go_relaxed.owl	regulation of inhibitory G-protein coupled receptor phosphorylation							sl	2015-06-10T19:46:37Z					biological_process											owl:Class	
GO:1990574	biolink:NamedThing	meiotic spindle astral microtubule	Any of the meiotic spindle microtubules that radiate in all directions from the spindle poles and are thought to contribute to the forces that separate the poles and position them in relation to the rest of the cell.	tmpzr1t_l9r_go_relaxed.owl								vw	2014-12-04T09:55:09Z					cellular_component											owl:Class	
GO:0042668	biolink:NamedThing	auditory receptor cell fate determination	The process in which a cell becomes capable of differentiating autonomously into an auditory hair cell regardless of its environment; upon determination, the cell fate cannot be reversed.	tmpzr1t_l9r_go_relaxed.owl	auditory hair cell fate determination													biological_process											owl:Class	
GO:0044652	biolink:NamedThing	adhesion of symbiont to host endothelial cell	The attachment of a symbiont to a host endothelial cell via adhesion molecules, general stickiness etc., either directly or indirectly.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-07-12T12:49:07Z					biological_process											owl:Class	
GO:0090539	biolink:NamedThing	peptide pheromone export by transmembrane transport	The directed movement of a peptide pheromone across a membrane and out of a cell.	tmpzr1t_l9r_go_relaxed.owl	peptide pheromone export by membrane transport							tb	2013-02-11T15:44:51Z					biological_process											owl:Class	
GO:0061241	biolink:NamedThing	mesonephric nephron epithelium development	The process whose specific outcome is the progression of the mesonephric nephron epithelium over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. The mesonephric nephron epithelium is a tissue that covers the surface of a nephron in the mesonephros.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-08-19T03:11:59Z					biological_process											owl:Class	
GO:0036167	biolink:NamedThing	phenotypic switching in response to host	A reversible switch of a cell from one phenotype to another that occurs upon infection of a host or host cell. For example, Candida albicans switches from a unicellular form to an invasive multicellular filamentous form upon infection of host tissue. Phenotypic switching begins with changes in cell morphology and altered gene expression patterns and ends when the morphology of a population of cells has reverted back to the default state, accompanied by altered expression patterns.	tmpzr1t_l9r_go_relaxed.owl								bf	2012-03-27T01:44:24Z					biological_process											owl:Class	
GO:0089710	biolink:NamedThing	endocytic targeting sequence binding	Binding to a endocytic signal sequence, a specific peptide sequence, of 4-6 amino acids with an essential tyrosine (Y), found on cytoplasmic tails of some cell surface membrane proteins, which directs internalization by clathrin-coated pits.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0034475	biolink:NamedThing	U4 snRNA 3'-end processing	Any process involved in forming the mature 3' end of a U4 snRNA molecule.	tmpzr1t_l9r_go_relaxed.owl	U4 snRNA 3' end processing													biological_process											owl:Class	
GO:0035060	biolink:NamedThing	brahma complex	A SWI/SNF-type complex that contains 8 to 14 proteins, including both conserved (core) and nonconserved components; contains the ATPase product of the Drosophila brm (brahma) or mammalian SMARCA2/BAF190B/BRM gene, or an ortholog thereof.	tmpzr1t_l9r_go_relaxed.owl	BRM complex													cellular_component											owl:Class	
GO:0031237	biolink:NamedThing	intrinsic component of periplasmic side of plasma membrane	The component of a plasma membrane consisting of gene products and protein complexes that penetrate the periplasmic side of the plasma membrane only, either directly or via some covalently attached hydrophobic anchor.	tmpzr1t_l9r_go_relaxed.owl	intrinsic to periplasmic side of plasma membrane|intrinsic to external leaflet of plasma membrane, in periplasmic space											GO:0031239		cellular_component											owl:Class	
GO:0009914	biolink:NamedThing	hormone transport	The directed movement of hormones into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0032476	biolink:NamedThing	decaprenyl diphosphate synthase complex	A complex that possesses di-trans,poly-cis-decaprenylcistransferase activity; involved in ubiquinone biosynthesis.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0050537	biolink:NamedThing	mandelamide amidase activity	Catalysis of the reaction: (R)-mandelamide + H(2)O = (R)-mandelate + NH(4)(+).	tmpzr1t_l9r_go_relaxed.owl	mandelamide hydrolase activity|Pseudomonas mandelamide hydrolase activity				RHEA:22876|KEGG_REACTION:R05783|EC:3.5.1.86|MetaCyc:3.5.1.86-RXN									molecular_function											owl:Class	
GO:0050629	biolink:NamedThing	tetrachloroethene reductive dehalogenase activity	Catalysis of the reaction: trichloroethene + chloride + acceptor = tetrachloroethene + reduced acceptor.	tmpzr1t_l9r_go_relaxed.owl	tetrachloroethene reductase activity|acceptor:trichloroethene oxidoreductase (chlorinating)				EC:1.21.99.5|RHEA:20353|MetaCyc:1.97.1.8-RXN									molecular_function											owl:Class	
GO:0071784	biolink:NamedThing	endoplasmic reticulum cisternal network assembly	The aggregation, arrangement and bonding together of a set of components to form the endoplasmic reticulum (ER) cisternal network. The ER cisternal network is the ER part that comprises the membranes with low curvature in cross-section.	tmpzr1t_l9r_go_relaxed.owl	endoplasmic reticulum cisternal network formation|ER cisternal network assembly|ER cisternal network formation							mah	2010-09-01T01:50:49Z					biological_process											owl:Class	
GO:0090427	biolink:NamedThing	activation of meiosis	Any process that starts the inactive process of meiosis.	tmpzr1t_l9r_go_relaxed.owl								tb	2012-05-04T09:50:19Z					biological_process											owl:Class	
GO:1903781	biolink:NamedThing	positive regulation of cardiac conduction	Any process that activates or increases the frequency, rate or extent of cardiac conduction.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of cardiac conduction|activation of cardiac conduction|up regulation of cardiac conduction|upregulation of cardiac conduction							rph	2015-01-07T13:20:28Z					biological_process											owl:Class	
GO:0019134	biolink:NamedThing	glucosamine-1-phosphate N-acetyltransferase activity	Catalysis of the reaction: alpha-D-glucosamine 1-phosphate + acetyl-CoA = N-acetyl-alpha-D-glucosamine 1-phosphate + CoA + H(+).	tmpzr1t_l9r_go_relaxed.owl	acetyl-CoA:D-glucosamine-1-phosphate N-acetyltransferase activity|acetyl-CoA:alpha-D-glucosamine-1-phosphate N-acetyltransferase activity				RHEA:13725|KEGG_REACTION:R05332|MetaCyc:2.3.1.157-RXN|EC:2.3.1.157									molecular_function											owl:Class	
GO:0000725	biolink:NamedThing	recombinational repair	A DNA repair process that involves the exchange, reciprocal or nonreciprocal, of genetic material between the broken DNA molecule and a homologous DNA region.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Recombinational_repair									biological_process											owl:Class	
GO:2000593	biolink:NamedThing	negative regulation of metanephric DCT cell differentiation	Any process that stops, prevents or reduces the frequency, rate or extent of metanephric DCT cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of metanephric distal convoluted tubule cell differentiation							yaf	2011-04-11T01:40:38Z					biological_process											owl:Class	
GO:0034379	biolink:NamedThing	very-low-density lipoprotein particle assembly	The non-covalent aggregation and arrangement of proteins and lipids in the liver to form a very-low-density lipoprotein particle.	tmpzr1t_l9r_go_relaxed.owl	VLDL assembly													biological_process											owl:Class	
GO:0045046	biolink:NamedThing	protein import into peroxisome membrane	The targeting of proteins into the peroxisomal membrane. The process is not well understood, but both signals and mechanism differ from those involved in peroxisomal matrix protein import.	tmpzr1t_l9r_go_relaxed.owl	peroxisome membrane protein import|protein transport into peroxisome membrane													biological_process											owl:Class	
GO:0001119	biolink:NamedThing	protein-DNA-RNA complex remodeling	The acquisition, loss, or modification of macromolecules within a protein-DNA-RNA complex, resulting in the alteration of an existing complex.	tmpzr1t_l9r_go_relaxed.owl								krc	2010-12-03T04:15:52Z					biological_process											owl:Class	
GO:0051970	biolink:NamedThing	negative regulation of transmission of nerve impulse	Any process that stops, prevents, or reduces the frequency, rate or extent of transmission of a nerve impulse, the sequential electrochemical polarization and depolarization that travels across the membrane of a neuron in response to stimulation.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of conduction of nerve impulse|inhibition of transmission of nerve impulse|down-regulation of transmission of nerve impulse|down regulation of transmission of nerve impulse|downregulation of transmission of nerve impulse													biological_process											owl:Class	
GO:0009139	biolink:NamedThing	pyrimidine nucleoside diphosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of pyrimidine nucleoside diphosphate, a compound consisting of a pyrimidine base linked to a ribose or deoxyribose sugar esterified with diphosphate on the sugar.	tmpzr1t_l9r_go_relaxed.owl	pyrimidine nucleoside diphosphate biosynthesis|pyrimidine nucleoside diphosphate formation|pyrimidine nucleoside diphosphate synthesis|pyrimidine nucleoside diphosphate anabolism													biological_process											owl:Class	
GO:0103006	biolink:NamedThing	9,10-dihydroxystearate hydroxylase activity	Catalysis of the reaction: H+ + (9R,10S)-dihydroxystearate + O2 + NADPH <=> 9,10,18-trihydroxystearate + H2O + NADP.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-9807									molecular_function											owl:Class	
GO:0045314	biolink:NamedThing	regulation of compound eye photoreceptor development	Any process that modulates the frequency, rate or extent of compound eye photoreceptor development.	tmpzr1t_l9r_go_relaxed.owl	regulation of eye photoreceptor development													biological_process											owl:Class	
GO:0042478	biolink:NamedThing	regulation of eye photoreceptor cell development	Any process that modulates the frequency, rate or extent of eye photoreceptor development.	tmpzr1t_l9r_go_relaxed.owl	regulation of eye photoreceptor development													biological_process											owl:Class	
GO:0060212	biolink:NamedThing	negative regulation of nuclear-transcribed mRNA poly(A) tail shortening	Any process that decreases the frequency, rate or extent of poly(A) tail shortening of a nuclear-transcribed mRNA. Poly(A) tail shortening is the decrease in length of the poly(A) tail of an mRNA from full length to an oligo(A) length.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of mRNA deadenylation|negative regulation of 3' to 5' mRNA deadenylation|negative regulation of nuclear mRNA poly(A) tail shortening													biological_process											owl:Class	
GO:1900152	biolink:NamedThing	negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	Any process that stops, prevents or reduces the frequency, rate or extent of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay.	tmpzr1t_l9r_go_relaxed.owl	down regulation of mRNA catabolic process, deadenylylation-dependent|inhibition of mRNA catabolism, deadenylation-dependent|down regulation of mRNA catabolic process, deadenylation-dependent|down-regulation of mRNA catabolic process, deadenylation-dependent|inhibition of mRNA catabolic process, deadenylylation-dependent|down regulation of mRNA breakdown, deadenylation-dependent decay|down regulation of deadenylation-dependent mRNA decay|down-regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay|down-regulation of mRNA catabolic process, deadenylylation-dependent|downregulation of mRNA catabolic process, deadenylylation-dependent|down-regulation of mRNA degradation, deadenylation-dependent decay|down-regulation of nuclear mRNA catabolic process, deadenylation-dependent decay|negative regulation of mRNA catabolism, deadenylation-dependent|down regulation of mRNA catabolism, deadenylylation-dependent|inhibition of mRNA catabolic process, deadenylation-dependent|down regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay|down regulation of mRNA catabolism, deadenylation-dependent|down-regulation of mRNA catabolism, deadenylylation-dependent|down-regulation of deadenylation-dependent mRNA decay|downregulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay|downregulation of mRNA catabolic process, deadenylation-dependent|down-regulation of mRNA catabolism, deadenylation-dependent|downregulation of mRNA degradation, deadenylation-dependent decay|inhibition of mRNA breakdown, deadenylation-dependent decay|down regulation of mRNA degradation, deadenylation-dependent decay|downregulation of deadenylation-dependent mRNA decay|negative regulation of mRNA degradation, deadenylation-dependent decay|inhibition of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay|negative regulation of mRNA breakdown, deadenylation-dependent decay|downregulation of mRNA breakdown, deadenylation-dependent decay|downregulation of nuclear mRNA catabolic process, deadenylation-dependent decay|negative regulation of nuclear mRNA catabolic process, deadenylation-dependent decay|negative regulation of mRNA catabolism, deadenylylation-dependent|downregulation of mRNA catabolism, deadenylylation-dependent|inhibition of mRNA degradation, deadenylation-dependent decay|down regulation of nuclear mRNA catabolic process, deadenylation-dependent decay|negative regulation of deadenylation-dependent mRNA decay|negative regulation of mRNA catabolic process, deadenylylation-dependent|down-regulation of mRNA breakdown, deadenylation-dependent decay|inhibition of deadenylation-dependent mRNA decay|inhibition of nuclear mRNA catabolic process, deadenylation-dependent decay|inhibition of mRNA catabolism, deadenylylation-dependent|downregulation of mRNA catabolism, deadenylation-dependent|negative regulation of mRNA catabolic process, deadenylation-dependent							bf	2012-03-07T09:14:49Z					biological_process											owl:Class	
GO:1902737	biolink:NamedThing	dendritic filopodium	A small, membranous protrusion found primarily on dendritic stretches of developing neurons. May receive synaptic input, and can develop into dendritic spines.	tmpzr1t_l9r_go_relaxed.owl	dendrite filopodium					Dendritic filopodia are generally less-well studied than dendritic spines because their transient nature makes them difficult to detect with traditional microscopy techniques, and because they are sometimes destroyed by sample preparation. Note that filopodia on dendritic shafts are distinct from other types of filopodia (even those found in dendritic growth cones) and may react differently to stimuli, as shown in PMID:12904473.		pr	2014-02-26T14:28:26Z					cellular_component											owl:Class	
GO:0102214	biolink:NamedThing	omega-hydroxy fatty acyl-CoA synthetase activity	Catalysis of the reaction: coenzyme A + ATP + an omega-hydroxy fatty acid = diphosphoric acid + AMP + a omega-hydroxyacyl-CoA.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-12185									molecular_function											owl:Class	
GO:0052023	biolink:NamedThing	modulation by symbiont of salicylic acid levels in host	The alteration by an organism of the levels of salicylic acid in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	modulation by organism of salicylic acid levels in other organism involved in symbiotic interaction											GO:0052469		biological_process											owl:Class	
GO:0099059	biolink:NamedThing	integral component of presynaptic active zone membrane	The component of the presynaptic active zone membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:2000973	biolink:NamedThing	regulation of pro-B cell differentiation	Any process that modulates the frequency, rate or extent of pro-B cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	regulation of pro-B cell development|regulation of pro-B lymphocyte differentiation							yaf	2011-08-02T03:05:45Z					biological_process											owl:Class	
GO:0035431	biolink:NamedThing	negative regulation of gluconate transmembrane transport	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of gluconate across a membrane by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of gluconate membrane transport|down-regulation of gluconate transport|inhibition of gluconate transport|negative regulation of gluconate transport|down regulation of gluconate transport|downregulation of gluconate transport							bf	2010-04-08T10:39:08Z			GO:0032894		biological_process											owl:Class	
GO:0097037	biolink:NamedThing	heme export	The directed movement of heme out of a cell or organelle.	tmpzr1t_l9r_go_relaxed.owl								pr	2011-04-11T10:39:22Z					biological_process											owl:Class	
GO:0060206	biolink:NamedThing	estrous cycle phase	The progression of physiological phases, occurring in the endometrium during the estrous cycle that recur at regular intervals during the reproductive years. The estrous cycle is an ovulation cycle where the endometrium is resorbed if pregnancy does not occur.	tmpzr1t_l9r_go_relaxed.owl						Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase. To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).								biological_process											owl:Class	
GO:0046739	biolink:NamedThing	transport of virus in multicellular host	The transport of a virus between cells in a multicellular organism. The cells can be adjacent or spatially separated (e.g. in different tissues or organs).	tmpzr1t_l9r_go_relaxed.owl	spread of virus in multicellular host|viral spread within multicellular host|spread of virus within multicellular host													biological_process											owl:Class	
GO:0030134	biolink:NamedThing	COPII-coated ER to Golgi transport vesicle	A vesicle with a coat formed of the COPII coat complex proteins. The COPII coat complex is formed by the Sec23p/Sec24p and the Sec13p/Sec31p heterodimers. COPII-associated vesicles transport proteins from the rough endoplasmic reticulum to the Golgi apparatus (anterograde transport).	tmpzr1t_l9r_go_relaxed.owl	ER to Golgi transport vesicle|COPII-coated vesicle|ER-Golgi transport vesicle|ER to Golgi constitutive secretory pathway transport vesicle|endoplasmic reticulum-Golgi transport vesicle|COPII vesicle|COPII-associated ER to Golgi transport vesicle|endoplasmic reticulum to Golgi transport vesicle|COPII-associated vesicle							pg	2017-06-22T16:26:57Z			GO:0140045|GO:0030138		cellular_component											owl:Class	
GO:0101020	biolink:NamedThing	estrogen 16-alpha-hydroxylase activity	Catalysis of the reaction: estrogen + donor-H2 + O2 = 16-alpha-hydroxyestrogen + H2O.	tmpzr1t_l9r_go_relaxed.owl	oestrogen 16-alpha-hydroxylase activity													molecular_function											owl:Class	
GO:0019165	biolink:NamedThing	thiamine kinase activity	Catalysis of the reaction: ATP + thiamine = ADP + 2 H(+) + thiamine phosphate.	tmpzr1t_l9r_go_relaxed.owl	ATP:thiamin phosphotransferase activity|thiamin kinase (phosphorylating)|thiamin phosphokinase activity|ATP:thiamine phosphotransferase activity|thiamin kinase activity				MetaCyc:THIKIN-RXN|KEGG_REACTION:R02134|RHEA:12012|EC:2.7.1.89									molecular_function											owl:Class	
GO:0019970	biolink:NamedThing	interleukin-11 binding	Binding to interleukin-11.	tmpzr1t_l9r_go_relaxed.owl	IL-11 binding													molecular_function											owl:Class	
GO:0021858	biolink:NamedThing	GABAergic neuron differentiation in basal ganglia	The process in which a neuroblast acquires the specialized structural and functional features of a GABAergic inhibitory neuron in the basal ganglia. Differentiation includes the processes involved in commitment of a neuroblast to a GABAergic neuron.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:2001113	biolink:NamedThing	negative regulation of cellular response to hepatocyte growth factor stimulus	Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to hepatocyte growth factor stimulus.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of cellular response to HGF stimulus							dph	2011-10-05T05:43:23Z					biological_process											owl:Class	
GO:1905520	biolink:NamedThing	positive regulation of presynaptic active zone assembly	Any process that activates or increases the frequency, rate or extent of presynaptic active zone assembly.	tmpzr1t_l9r_go_relaxed.owl	upregulation of presynaptic active zone formation|activation of presynaptic active zone formation|up regulation of presynaptic active zone formation|upregulation of pre-synaptic active zone assembly|up regulation of pre-synaptic active zone component assembly|up-regulation of pre-synaptic active zone formation|upregulation of presynaptic active zone assembly|activation of pre-synaptic active zone component formation|up-regulation of presynaptic active zone assembly|up-regulation of pre-synaptic active zone component assembly|up regulation of presynaptic active zone assembly|up regulation of pre-synaptic active zone formation|positive regulation of pre-synaptic active zone formation|positive regulation of pre-synaptic active zone assembly|positive regulation of pre-synaptic active zone component formation|upregulation of pre-synaptic active zone formation|positive regulation of pre-synaptic active zone component assembly|activation of pre-synaptic active zone assembly|up-regulation of pre-synaptic active zone assembly|activation of pre-synaptic active zone formation|upregulation of pre-synaptic active zone component assembly|up regulation of pre-synaptic active zone component formation|positive regulation of presynaptic active zone formation|up regulation of pre-synaptic active zone assembly|activation of pre-synaptic active zone component assembly|up-regulation of presynaptic active zone formation|activation of presynaptic active zone assembly|up-regulation of pre-synaptic active zone component formation|upregulation of pre-synaptic active zone component formation							rl	2016-10-01T09:38:07Z					biological_process											owl:Class	
GO:0015333	biolink:NamedThing	peptide:proton symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: peptide(out) + H+(out) = peptide(in) + H+(in), up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by hydrogen ion movement.	tmpzr1t_l9r_go_relaxed.owl	peptide:hydrogen symporter activity				Reactome:R-HSA-428007|RHEA:37047|Reactome:R-HSA-427998									molecular_function											owl:Class	
GO:0061621	biolink:NamedThing	canonical glycolysis	The glycolytic process that begins with the conversion of glucose to glucose-6-phosphate by glucokinase activity. Glycolytic processes are the  chemical reactions and pathways resulting in the breakdown of a carbohydrate into pyruvate, with the concomitant production of a small amount of ATP.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:PWY66-400|Reactome:R-HSA-70171|MetaCyc:ANAGLYCOLYSIS-PWY|Wikipedia:Glycolysis			dph	2014-04-14T09:21:54Z					biological_process											owl:Class	
GO:0035742	biolink:NamedThing	activated CD8-positive, alpha-beta T cell proliferation	The expansion of an activated CD8-positive, alpha-beta T cell population by cell division.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-03-17T02:19:58Z					biological_process											owl:Class	
GO:0008918	biolink:NamedThing	lipopolysaccharide 3-alpha-galactosyltransferase activity	Catalysis of the reaction: UDP-galactose + lipopolysaccharide = UDP + 1,3 alpha-D-galactosyl-lipopolysaccharide.	tmpzr1t_l9r_go_relaxed.owl	uridine diphosphate galactose:lipopolysaccharide alpha-3-galactosyltransferase activity|LPS 3-alpha-galactosyltransferase activity|UDPgalactose:lipopolysaccharide 3-alpha-D-galactosyltransferase activity|lipopolysaccharide-alpha-1,3-D-galactosyltransferase|UDP-galactose:lipopolysaccharide alpha,3-galactosyltransferase activity|UDP-galactose:polysaccharide galactosyltransferase activity|uridine diphosphogalactose-lipopolysaccharide alpha,3-galactosyltransferase activity|lipopolysaccharide galactosyltransferase activity|UDP-galactose:lipopolysaccharide 3-alpha-D-galactosyltransferase activity|lipopolysaccharide 1,3-galactosyltransferase activity				EC:2.4.1.44|MetaCyc:2.4.1.44-RXN									molecular_function											owl:Class	
GO:0047762	biolink:NamedThing	caffeate 3,4-dioxygenase activity	Catalysis of the reaction: trans-caffeate + O(2) = 3-(2-carboxyethenyl)-cis,cis-muconate + 2 H(+).	tmpzr1t_l9r_go_relaxed.owl	3,4-dihydroxy-trans-cinnamate:oxygen 3,4-oxidoreductase (decyclizing)				EC:1.13.11.22|KEGG_REACTION:R03365|MetaCyc:CAFFEATE-34-DIOXYGENASE-RXN|RHEA:22216									molecular_function											owl:Class	
GO:0019349	biolink:NamedThing	ribitol metabolic process	The chemical reactions and pathways involving ribitol, a pentitol derived formally by reduction of the -CHO group of either D- or L-ribose. It occurs free in some plants and is a component of riboflavin.	tmpzr1t_l9r_go_relaxed.owl	ribitol metabolism													biological_process											owl:Class	
GO:0000011	biolink:NamedThing	vacuole inheritance	The distribution of vacuoles into daughter cells after mitosis or meiosis, mediated by interactions between vacuoles and the cytoskeleton.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0000719	biolink:NamedThing	photoreactive repair	The repair of UV-induced T-T, C-T and C-C dimers by directly reversing the damage to restore the original pyrimidines.	tmpzr1t_l9r_go_relaxed.owl	pyrimidine-dimer repair by photolyase													biological_process											owl:Class	
GO:0018620	biolink:NamedThing	phthalate 4,5-dioxygenase activity	Catalysis of the reaction: H(+) + NADH + O(2) + phthalate = cis-4,5-dihydroxycyclohexa-2,6-diene-1,2-dicarboxylate + NAD(+).	tmpzr1t_l9r_go_relaxed.owl	phthalate dioxygenase activity|PDO activity|phthalate,NADH:oxygen oxidoreductase (4,5-hydroxylating)				UM-BBD_reactionID:r0102|MetaCyc:PHTHALATE-45-DIOXYGENASE-RXN|RHEA:17489|EC:1.14.12.7|KEGG_REACTION:R03630									molecular_function											owl:Class	
GO:0033638	biolink:NamedThing	modulation by symbiont of host response to heat	Any process in which an organism modulates a change in state or activity of a host cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	response to heat shock													biological_process											owl:Class	
GO:0070731	biolink:NamedThing	cGMP transport	The directed movement of cyclic GMP (cGMP), into, out of or within a cell.	tmpzr1t_l9r_go_relaxed.owl	cyclic GMP transport							mah	2009-06-17T04:40:27Z					biological_process											owl:Class	
GO:0061239	biolink:NamedThing	mesenchymal stem cell differentiation involved in mesonephric nephron morphogenesis	The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal stem cell that contributes to the shaping of a nephronin the mesonephros. A mesenchymal stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-08-19T03:06:46Z					biological_process											owl:Class	
GO:0000404	biolink:NamedThing	heteroduplex DNA loop binding	Binding to a DNA segment containing a loop. A loop occurs when DNA contains a large insertion or deletion that causes a region of unpaired single-stranded DNA to loop out, while the rest of the DNA is in a paired double-stranded configuration.	tmpzr1t_l9r_go_relaxed.owl	loop DNA binding													molecular_function											owl:Class	
GO:0010301	biolink:NamedThing	xanthoxin dehydrogenase activity	Catalysis of the reaction: NAD(+) + xanthoxin = (+)-abscisic aldehyde + H(+) + NADH.	tmpzr1t_l9r_go_relaxed.owl	xanthoxin oxidase activity|xanthoxin:NAD+ oxidoreductase activity|ABA2				KEGG_REACTION:R06954|MetaCyc:1.1.1.288-RXN|RHEA:12548|EC:1.1.1.288							GO:0033710		molecular_function											owl:Class	
GO:0102458	biolink:NamedThing	cyanidin 3-O-glucoside 5-O glucosyltransferase (vanilloyl-glucose dependent) activity	Catalysis of the reaction: cyanidin 3-O-beta-D-glucoside betaine + 1-O-vanilloyl-beta-D-glucose <=> cyanin betaine + vanillate + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-13970|EC:2.4.1.299									molecular_function											owl:Class	
GO:0006148	biolink:NamedThing	inosine catabolic process	The chemical reactions and pathways resulting in the breakdown of inosine, hypoxanthine riboside, a nucleoside found free but not in combination in nucleic acids except in the anticodons of some tRNAs.	tmpzr1t_l9r_go_relaxed.owl	inosine breakdown|inosine degradation|inosine catabolism													biological_process											owl:Class	
GO:0044349	biolink:NamedThing	DNA excision	The removal of a section of DNA from a larger DNA molecule by the making of dual incisions that flank the section to be excised.	tmpzr1t_l9r_go_relaxed.owl								jl	2011-08-03T10:56:37Z					biological_process											owl:Class	
GO:0106078	biolink:NamedThing	histone succinyltransferase activity	Catalysis of the reaction: succinyl-CoA + histone = CoA + succinyl-histone.	tmpzr1t_l9r_go_relaxed.owl								hjd	2017-12-15T18:29:40Z					molecular_function											owl:Class	
GO:0106075	biolink:NamedThing	peptide N-succinyltransferase activity	Catalysis of the acetylation of an amino acid residue of a peptide or protein, according to the reaction: succinyl-CoA + peptide = CoA + N-succinylpeptide.	tmpzr1t_l9r_go_relaxed.owl								hjd	2017-12-15T18:23:58Z					molecular_function											owl:Class	
GO:0060904	biolink:NamedThing	regulation of protein folding in endoplasmic reticulum	Any process that modulates the rate, frequency or extent of the protein folding process that takes place in the endoplasmic reticulum (ER). Secreted, plasma membrane and organelle proteins are folded in the ER, assisted by chaperones and foldases (protein disulphide isomerases), and additional factors required for optimal folding (ATP, Ca2+ and an oxidizing environment to allow disulfide bond formation).	tmpzr1t_l9r_go_relaxed.owl								dph	2009-08-14T01:12:00Z					biological_process											owl:Class	
GO:0042719	biolink:NamedThing	mitochondrial intermembrane space protein transporter complex	Soluble complex of the mitochondrial intermembrane space composed of various combinations of small Tim proteins; acts as a protein transporter to guide proteins to the Tim22 complex for insertion into the mitochondrial inner membrane.	tmpzr1t_l9r_go_relaxed.owl	Tim9-Tim10 complex													cellular_component											owl:Class	
GO:1904284	biolink:NamedThing	positive regulation of antigen processing and presentation of endogenous peptide antigen via MHC class I	Any process that activates or increases the frequency, rate or extent of antigen processing and presentation of endogenous peptide antigen via MHC class I.	tmpzr1t_l9r_go_relaxed.owl	activation of antigen processing and presentation of endogenous peptide antigen via MHC class I|up-regulation of antigen processing and presentation of endogenous peptide antigen via MHC class I|up regulation of antigen processing and presentation of endogenous peptide antigen via MHC class I|activation of endogenous peptide antigen processing and presentation via MHC class I|up regulation of endogenous peptide antigen processing and presentation via MHC class I|positive regulation of endogenous peptide antigen processing and presentation via MHC class I|upregulation of antigen processing and presentation of endogenous peptide antigen via MHC class I|up-regulation of endogenous peptide antigen processing and presentation via MHC class I|upregulation of endogenous peptide antigen processing and presentation via MHC class I							rl	2015-06-04T12:05:49Z					biological_process											owl:Class	
GO:1990830	biolink:NamedThing	cellular response to leukemia inhibitory factor	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leukemia inhibitory factor stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to cholinergic differentiation factor|cellular response to CDF							sl	2015-08-20T19:30:38Z					biological_process											owl:Class	
GO:1990823	biolink:NamedThing	response to leukemia inhibitory factor	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leukemia inhibitory factor stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to cholinergic differentiation factor|response to CDF|response to LIF							sl	2015-08-19T16:44:21Z					biological_process											owl:Class	
GO:0097629	biolink:NamedThing	extrinsic component of omegasome membrane	The component of the omegasome membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.	tmpzr1t_l9r_go_relaxed.owl	omegasome peripheral membrane|extrinsic to omegasome membrane													cellular_component											owl:Class	
GO:1905442	biolink:NamedThing	cellular response to chondroitin 4'-sulfate	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chondroitin 4'-sulfate stimulus.	tmpzr1t_l9r_go_relaxed.owl								cvs	2016-09-14T18:56:34Z					biological_process											owl:Class	
GO:1901974	biolink:NamedThing	glycerate transmembrane transporter activity	Enables the transfer of glycerate from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl								ms	2013-03-05T16:48:45Z					molecular_function											owl:Class	
GO:0097144	biolink:NamedThing	BAX complex	An oligomeric protein complex consisting of BAX, a member of the Bcl-2 family of anti- and proapoptotic regulators.	tmpzr1t_l9r_go_relaxed.owl								pr	2011-08-02T01:45:15Z					cellular_component											owl:Class	
GO:0033637	biolink:NamedThing	modulation by symbiont of host response to cold	Any process in which an organism modulates a change in state or activity of a host cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	freezing tolerance													biological_process											owl:Class	
GO:0004317	biolink:NamedThing	3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity	Catalysis of the reaction: (3R)-3-hydroxypalmitoyl-[acyl-carrier protein] = 2-hexadecenoyl-[acyl-carrier protein] + H2O.	tmpzr1t_l9r_go_relaxed.owl	(3R)-3-hydroxypalmitoyl-acyl-carrier-protein hydro-lyase (hexadec-2-enoyl-acyl-carrier protein-forming)|(3R)-3-hydroxypalmitoyl-acyl-carrier-protein hydro-lyase activity|3-hydroxypalmitoyl-[acyl-carrier protein] dehydratase activity|D-3-hydroxypalmitoyl-acyl-carrier-protein dehydratase activity|(3R)-3-hydroxypalmitoyl-[acyl-carrier-protein] hydro-lyase activity|3-hydroxypalmitoyl-ACP dehydratase activity|3-hydroxypalmitoyl-acyl-carrier-protein dehydratase activity|beta-hydroxypalmitoyl thioester dehydratase activity|beta-hydroxypalmitoyl-acyl carrier protein dehydrase activity|beta-hydroxypalmityl-ACP dehydrase activity|D-3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity				RHEA:41908|MetaCyc:4.2.1.61-RXN|EC:4.2.1.59|KEGG_REACTION:R04462									molecular_function											owl:Class	
GO:0106263	biolink:NamedThing	1-acylglycerophosphoserine O-acyltransferase activity	Catalysis of the reaction:a 1-acyl-sn-glycero-3-phospho-L-serine + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phospho-L-serine + CoA.	tmpzr1t_l9r_go_relaxed.owl					RHEA:33191			hjd	2020-05-18T15:12:42Z					molecular_function											owl:Class	
GO:2000716	biolink:NamedThing	negative regulation of maintenance of mitotic sister chromatid cohesion, arms	Any process that stops, prevents or reduces the frequency, rate or extent of maintenance of mitotic sister chromatid cohesion along the chromosome arms.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of maintenance of mitotic sister chromatin cohesion along arms|negative regulation of maintenance of sister chromatin cohesion along arms at mitosis							mah	2011-06-03T10:38:32Z					biological_process											owl:Class	
GO:0009217	biolink:NamedThing	purine deoxyribonucleoside triphosphate catabolic process	The chemical reactions and pathways resulting in the breakdown of purine deoxyribonucleoside triphosphate, a compound consisting of a purine base linked to a deoxyribose sugar esterified with triphosphate on the sugar.	tmpzr1t_l9r_go_relaxed.owl	purine deoxyribonucleoside triphosphate breakdown|purine deoxyribonucleoside triphosphate catabolism|purine deoxyribonucleoside triphosphate degradation													biological_process											owl:Class	
GO:0010510	biolink:NamedThing	regulation of acetyl-CoA biosynthetic process from pyruvate	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of acetyl-CoA from pyruvate.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0110063	biolink:NamedThing	positive regulation of angiotensin-activated signaling pathway	Any process that activates or increases the frequency, rate or extent of the angiotensin-activated signaling pathway.	tmpzr1t_l9r_go_relaxed.owl								kmv	2017-10-26T17:47:37Z					biological_process											owl:Class	
GO:0035227	biolink:NamedThing	regulation of glutamate-cysteine ligase activity	Any process that modulates the activity of glutamate-cysteine ligase.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0097438	biolink:NamedThing	exit from dormancy	The dormancy process that results in exit from dormancy. Dormancy (sometimes called a dormant state) is a suspension of most physiological activity and growth that can be reactivated.	tmpzr1t_l9r_go_relaxed.owl	release from dormancy							pr	2012-12-05T15:01:24Z					biological_process											owl:Class	
GO:0047567	biolink:NamedThing	3-methyleneoxindole reductase activity	Catalysis of the reaction: 3-methyloxindole + NADP(+) = 3-methyleneoxindole + H(+) + NADPH.	tmpzr1t_l9r_go_relaxed.owl	3-methyloxindole:NADP+ oxidoreductase activity|3-methyl-1,3-dihydroindol-2-one:NADP+ oxidoreductase activity				RHEA:20257|MetaCyc:3-METHYLENEOXINDOLE-REDUCTASE-RXN|EC:1.3.1.17|KEGG_REACTION:R03930									molecular_function											owl:Class	
GO:0035504	biolink:NamedThing	regulation of myosin light chain kinase activity	Any process that modulates the frequency, rate or extent of myosin light chain kinase activity.	tmpzr1t_l9r_go_relaxed.owl								bf	2010-04-30T10:47:11Z					biological_process											owl:Class	
GO:0061191	biolink:NamedThing	positive regulation of vacuole fusion, non-autophagic	Any process that increases the frequency, rate or extent of the fusion of two vacuole membranes to form a single vacuole.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-07-14T09:33:31Z					biological_process											owl:Class	
GO:0006801	biolink:NamedThing	superoxide metabolic process	The chemical reactions and pathways involving superoxide, the superoxide anion O2- (superoxide free radical), or any compound containing this species.	tmpzr1t_l9r_go_relaxed.owl	oxygen free radical metabolic process|oxygen free radical metabolism|superoxide free radical metabolism|superoxide free radical metabolic process|superoxide metabolism													biological_process											owl:Class	
GO:0003133	biolink:NamedThing	endodermal-mesodermal cell signaling	Any process that mediates the transfer of information from endodermal cells to mesodermal cells.	tmpzr1t_l9r_go_relaxed.owl	endodermal-mesodermal cell signalling							tb	2009-09-22T03:10:29Z					biological_process											owl:Class	
GO:0004594	biolink:NamedThing	pantothenate kinase activity	Catalysis of the reaction: ATP + pantothenate = ADP + D-4'-phosphopantothenate.	tmpzr1t_l9r_go_relaxed.owl	pantothenic acid kinase activity|ATP:(R)-pantothenate 4'-phosphotransferase activity|pantothenate kinase (phosphorylating) activity|ATP:pantothenate 4'-phosphotransferase activity|D-pantothenate kinase activity				MetaCyc:PANTOTHENATE-KIN-RXN|Reactome:R-HSA-199203|EC:2.7.1.33|RHEA:16373|Reactome:R-HSA-196857									molecular_function											owl:Class	
GO:0005927	biolink:NamedThing	muscle tendon junction	A cell-substrate junction found at the terminal anchorage site of skeletal muscle cells to tendons.	tmpzr1t_l9r_go_relaxed.owl	myotendinous junction													cellular_component											owl:Class	
GO:0031750	biolink:NamedThing	D3 dopamine receptor binding	Binding to a D3 dopamine receptor.	tmpzr1t_l9r_go_relaxed.owl	D3 dopamine receptor ligand													molecular_function											owl:Class	
GO:0018952	biolink:NamedThing	parathion metabolic process	The chemical reactions and pathways involving parathion, a highly toxic organophosphate compound formerly used as a broad spectrum insecticide, acaricide, fumigant and nematocide. Degradation of parathion by sunlight or liver enzymes can result in the formation of the active compound paraoxon which interferes with the nervous system through cholinesterase inhibition.	tmpzr1t_l9r_go_relaxed.owl	parathion metabolism				UM-BBD_pathwayID:pthn									biological_process											owl:Class	
GO:0002261	biolink:NamedThing	mucosal lymphocyte homeostasis	The process of regulating the proliferation and elimination of lymphocytes such that the total number of lymphocytes within the mucosal tissue of an organism is stable over time in the absence of an outside stimulus.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1901959	biolink:NamedThing	positive regulation of cutin biosynthetic process	Any process that activates or increases the frequency, rate or extent of cutin biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of cutin biosynthesis|positive regulation of cutin formation|upregulation of cutin synthesis|activation of cutin formation|activation of cutin anabolism|upregulation of cutin formation|upregulation of cutin anabolism|up regulation of cutin anabolism|positive regulation of cutin anabolism|positive regulation of cutin synthesis|activation of cutin biosynthetic process|upregulation of cutin biosynthesis|activation of cutin biosynthesis|up regulation of cutin synthesis|up regulation of cutin formation|up-regulation of cutin formation|up-regulation of cutin anabolism|positive regulation of cutin biosynthesis|up regulation of cutin biosynthesis|activation of cutin synthesis|upregulation of cutin biosynthetic process|up regulation of cutin biosynthetic process|up-regulation of cutin biosynthetic process|up-regulation of cutin synthesis							tb	2013-02-19T19:06:19Z					biological_process											owl:Class	
GO:0016939	biolink:NamedThing	kinesin II complex	A complex consisting of two distinct motor subunits that form a heterodimer complexed with a third non-motor accessory subunit, the kinesin associated protein or KAP; the KIF3 heterodimer interacts via its C-terminal portion with KAP, which is thought to regulate the binding of the motor to cargo membranes.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0030497	biolink:NamedThing	fatty acid elongation	The elongation of a fatty acid chain by the sequential addition of two-carbon units.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0008160	biolink:NamedThing	protein tyrosine phosphatase activator activity	Binds to and increases the activity of a phosphatase, an enzyme which catalyzes of the removal of a phosphate group from a tyrosyl phenolic group of a protein.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0050588	biolink:NamedThing	apo-beta-carotenoid-14',13'-dioxygenase activity	Catalysis of the reaction: 8'-apo-beta-carotenol + O(2) = (E,E)-7-hydroxy-6-methylhepta-3,5-dienal + 14'-apo-beta-carotenal.	tmpzr1t_l9r_go_relaxed.owl	apo-b-carotenoid-14',13'-dioxygenase activity|8'-apo-beta-carotenol:O2 oxidoreductase activity				KEGG_REACTION:R08889|MetaCyc:1.13.12.12-RXN|RHEA:26023|EC:1.13.11.67									molecular_function											owl:Class	
GO:2001025	biolink:NamedThing	positive regulation of response to drug	Any process that activates or increases the frequency, rate or extent of response to drug.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of drug susceptibility/resistance|positive regulation of drug resistance							yaf	2011-08-19T01:47:27Z					biological_process											owl:Class	
GO:2001023	biolink:NamedThing	regulation of response to drug	Any process that modulates the frequency, rate or extent of response to drug.	tmpzr1t_l9r_go_relaxed.owl	regulation of drug resistance|regulation of drug susceptibility/resistance							yaf	2011-08-19T01:47:20Z					biological_process											owl:Class	
GO:0070740	biolink:NamedThing	tubulin-glutamic acid ligase activity	Catalysis of the posttranslational transfer of one or more glutamate residues to the gamma-carboxyl group(s) of one or more specific glutamate residues on a tubulin molecule.	tmpzr1t_l9r_go_relaxed.owl	tubulin glutamylase activity|tubulin-glutamate ligase activity				Reactome:R-HSA-8865774|Reactome:R-HSA-8955869			mah	2009-06-19T02:26:15Z					molecular_function											owl:Class	
GO:0050618	biolink:NamedThing	phycoerythrobilin:ferredoxin oxidoreductase activity	Catalysis of the reaction: (3Z)-phycoerythrobilin + oxidized ferredoxin = 15,16-dihydrobiliverdin + reduced ferredoxin.	tmpzr1t_l9r_go_relaxed.owl	PebB|(3Z)-phycoerythrobilin:ferredoxin oxidoreductase activity				RHEA:22092|MetaCyc:1.3.7.3-RXN|EC:1.3.7.3									molecular_function											owl:Class	
GO:1903698	biolink:NamedThing	positive regulation of microvillus assembly	Any process that activates or increases the frequency, rate or extent of microvillus assembly.	tmpzr1t_l9r_go_relaxed.owl	up regulation of microvillus assembly|up-regulation of microvillus biogenesis|up-regulation of microvillus assembly|activation of microvillus assembly|up regulation of microvillus biogenesis|activation of microvillus biogenesis|positive regulation of microvillus biogenesis|upregulation of microvillus assembly|upregulation of microvillus biogenesis							als	2014-12-03T11:45:17Z					biological_process											owl:Class	
GO:2000410	biolink:NamedThing	regulation of thymocyte migration	Any process that modulates the frequency, rate or extent of thymocyte migration.	tmpzr1t_l9r_go_relaxed.owl	regulation of immature T-lymphocyte migration|regulation of immature T-cell migration|regulation of immature T cell migration|regulation of thymic lymphocyte migration|regulation of immature T lymphocyte migration							mah	2011-02-23T01:33:32Z					biological_process											owl:Class	
GO:0097255	biolink:NamedThing	R2TP complex	A highly conserved protein complex comprised of two ATP-dependent DNA helicases (Rvb1p and Rvb2p in yeast, Pontin52 and Reptin52 in humans), Pih1p in yeast or PIH1D1 in humans, and Tah1 in yeast or RPAP3 in humans. The complex associates with Hsp90 and is thought to have a role in assembly of large protein or protein/nucleic acid complexes. In this role it is involved in multiple processes such as box C/D snoRNP biogenesis, phosphatidylinositol-3 kinase-related protein kinase (PIKK) signaling, RNA polymerase II assembly, and others.	tmpzr1t_l9r_go_relaxed.owl								pr	2012-03-06T11:16:33Z					cellular_component											owl:Class	
GO:0043399	biolink:NamedThing	tRNA A64-2'-O-ribosylphosphate transferase activity	Catalysis of the transfer of a phosphoribosyl group from 5'-phosphoribosyl-1'-pyrophosphate to position 64 of initiator tRNA.	tmpzr1t_l9r_go_relaxed.owl	initiator tRNA phosphoribosyl-transferase activity													molecular_function											owl:Class	
GO:0106378	biolink:NamedThing	2-hydroxy-dATP hydrolase activity	Catalysis of the reaction: 2-hydroxy-dATP + H2O = 2-hydroxy-dAMP + diphosphate.	tmpzr1t_l9r_go_relaxed.owl					RHEA:31583			hjd	2021-04-23T00:14:20Z					molecular_function											owl:Class	
GO:0004371	biolink:NamedThing	glycerone kinase activity	Catalysis of the reaction: ATP + glycerone = ADP + glycerone phosphate + 2 H(+).	tmpzr1t_l9r_go_relaxed.owl	ATP:glycerone phosphotransferase activity|dihydroxyacetone kinase activity|acetol kinase (phosphorylating)|acetol kinase activity				MetaCyc:GLYCERONE-KINASE-RXN|EC:2.7.1.29|KEGG_REACTION:R01011|RHEA:15773									molecular_function											owl:Class	
GO:0046782	biolink:NamedThing	regulation of viral transcription	Any process that modulates the frequency, rate or extent of the transcription of the viral genome.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1902575	biolink:NamedThing	protein localization to cell division site involved in cytokinesis, actomyosin contractile ring assembly	Any protein localization to cell division site that is involved in cytokinesis, actomyosin contractile ring assembly.	tmpzr1t_l9r_go_relaxed.owl	protein localization to cell division site involved in cytokinesis, actomyosin ring formation|protein localisation to cell division site involved in cytokinesis, actomyosin ring formation|protein localisation to cell division site involved in contractile ring assembly|protein localization to cell division site involved in cytokinesis, actomyosin contractile ring formation|protein localisation to cell division site involved in constriction ring assembly|protein localization to cell division site involved in constriction ring assembly|protein localisation to cell division site involved in cytokinesis, actomyosin ring biosynthesis|protein localization to cell division site involved in contractile ring assembly|protein localization to cell division site involved in cytokinesis, contractile ring assembly|protein localisation to cell division site involved in cytokinesis, actomyosin contractile ring assembly|protein localization to cell division site involved in cytokinesis, actomyosin ring biosynthesis|protein localisation to cell division site involved in cytokinesis, contractile ring assembly|protein localisation to cell division site involved in cytokinesis, actomyosin contractile ring formation							bf	2013-12-16T10:42:25Z					biological_process											owl:Class	
GO:0021812	biolink:NamedThing	neuronal-glial interaction involved in cerebral cortex radial glia guided migration	The changes in adhesion between neuronal cells and glial cells as a component of the process of cerebral cortex glial-mediated radial cell migration.	tmpzr1t_l9r_go_relaxed.owl	neuronal-glial interaction involved in cerebral cortex glial-mediated radial migration													biological_process											owl:Class	
GO:0044071	biolink:NamedThing	modulation by symbiont of host cell cycle	The process in which a symbiont organism effects a change in its host's cell cycle through direct interactions with the host cell macromolecular machinery.	tmpzr1t_l9r_go_relaxed.owl	modulation of host cell cycle by symbiont|regulation by symbiont of host cell cycle|modification by symbiont of host cell cycle													biological_process											owl:Class	
GO:0008713	biolink:NamedThing	ADP-heptose-lipopolysaccharide heptosyltransferase activity	Catalysis of the reaction: heptosyl-KDO2-lipid A + ADP-L-glycero-beta-D-manno-heptose = heptosyl2-KDO2-lipid A + ADP + H+.	tmpzr1t_l9r_go_relaxed.owl	ADP-heptose:LPS heptosyltransferase activity				MetaCyc:RXN0-5061|RHEA:28538									molecular_function											owl:Class	
GO:1905800	biolink:NamedThing	negative regulation of intraciliary retrograde transport	Any process that stops, prevents or reduces the frequency, rate or extent of intraciliary retrograde transport.	tmpzr1t_l9r_go_relaxed.owl	down regulation of intraflagellar retrograde transport|down-regulation of intraciliary retrograde transport|inhibition of intraciliary retrograde transport|down-regulation of intraflagellar retrograde transport|downregulation of intraciliary retrograde transport|inhibition of intraflagellar retrograde transport|downregulation of intraflagellar retrograde transport|down regulation of intraciliary retrograde transport|negative regulation of intraflagellar retrograde transport							hbye	2017-01-11T12:58:26Z					biological_process											owl:Class	
GO:0009532	biolink:NamedThing	plastid stroma	The proteinaceous ground substance of plastids.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0044394	biolink:NamedThing	protein malonylation	The modification of a protein amino acid by the addition of a malonyl (CO-CH2-CO) group.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-12-12T09:26:37Z					biological_process											owl:Class	
GO:1905415	biolink:NamedThing	positive regulation of dense core granule exocytosis	Any process that activates or increases the frequency, rate or extent of dense core granule exocytosis.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of dense core granule exocytosis|upregulation of dense core granule exocytosis|upregulation of dense core vesicle exocytosis|up-regulation of dense core vesicle exocytosis|up regulation of dense core vesicle exocytosis|activation of dense core vesicle exocytosis|activation of dense core granule exocytosis|up regulation of dense core granule exocytosis|positive regulation of dense core vesicle exocytosis							bf	2016-08-31T08:02:36Z					biological_process											owl:Class	
GO:0046502	biolink:NamedThing	uroporphyrinogen III metabolic process	The chemical reactions and pathways involving uroporphyrinogen III, a precursor for synthesis of vitamin B12, chlorophyll, and heme in organisms that produce these compounds.	tmpzr1t_l9r_go_relaxed.owl	uroporphyrinogen III metabolism													biological_process											owl:Class	
GO:0050632	biolink:NamedThing	propionyl-CoA C2-trimethyltridecanoyltransferase activity	Catalysis of the reaction: 4,8,12-trimethyltridecanoyl-CoA + propanoyl-CoA = 3-oxopristanoyl-CoA + CoA.	tmpzr1t_l9r_go_relaxed.owl	peroxisomal 3-oxoacyl coenzyme A thiolase|sterol carrier protein X-related thiolase activity|oxopristanoyl-CoA thiolase activity|3-oxopristanoyl-CoA hydrolase activity|sterol carrier protein|4,8,12-trimethyltridecanoyl-CoA:propanoyl-CoA C2-4,8,12-trimethyltridecanoyltransferase activity|SCPx|4,8,12-trimethyltridecanoyl-CoA:propanoyl-CoA 2-C-4,8,12-trimethyltridecanoyltransferase activity|3-oxopristanoyl-CoA thiolase activity|propionyl-CoA C(2)-trimethyltridecanoyltransferase activity|peroxisome sterol carrier protein thiolase				Reactome:R-HSA-192341|Reactome:R-HSA-2066781|Reactome:R-HSA-390224|EC:2.3.1.176|RHEA:10408|Reactome:R-HSA-193533|KEGG_REACTION:R05330|MetaCyc:2.3.1.154-RXN							GO:0004770		molecular_function											owl:Class	
GO:0062137	biolink:NamedThing	cargo receptor complex	Any protein complex that is part of a membrane and which functions as a cargo receptor.	tmpzr1t_l9r_go_relaxed.owl								dph	2019-07-08T18:09:01Z					cellular_component											owl:Class	
GO:0102752	biolink:NamedThing	1,4-alpha-glucan branching enzyme activity (using a glucosylated glycogenin as primer for glycogen synthesis)	Catalysis of the reaction: a glucosylated glycogenin = a glycogen.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-7669|EC:2.4.1.18									molecular_function											owl:Class	
GO:1903673	biolink:NamedThing	mitotic cleavage furrow formation	Any cleavage furrow formation that is involved in mitotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl	cleavage furrow positioning involved in mitotic cell cycle							jl	2014-11-27T15:32:18Z					biological_process											owl:Class	
GO:0008564	biolink:NamedThing	protein-exporting ATPase activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + protein+(in) -> ADP + phosphate + protein+(out); drives the concomitant secretion of proteins.	tmpzr1t_l9r_go_relaxed.owl	ATPase-coupled protein transporter activity				MetaCyc:3.6.3.50-RXN|EC:7.4.2.8	Represents ATP- hydrolyzing enzymes of the general secretory pathway (Sec or Type II), of the virulence-related secretory pathway (Type III) and of the conjugal DNA-protein transfer pathway (Type IV). Type II enzymes occur in bacteria, archaea and eukaryotes, whereas type III and type IV enzymes occur in bacteria where they form components of a multi-subunit complex.								molecular_function											owl:Class	
GO:0050404	biolink:NamedThing	zeatin O-beta-D-xylosyltransferase activity	Catalysis of the reaction: UDP-alpha-D-xylose + zeatin = O-beta-D-xylosylzeatin + H(+) + UDP.	tmpzr1t_l9r_go_relaxed.owl	zeatin O-b-D-xylosyltransferase activity|zeatin O-xylosyltransferase activity|uridine diphosphoxylose-zeatin xylosyltransferase activity|UDP-D-xylose:zeatin O-beta-D-xylosyltransferase activity				KEGG_REACTION:R02119|RHEA:14721|MetaCyc:ZEATIN-O-BETA-D-XYLOSYLTRANSFERASE-RXN|EC:2.4.2.40	Note that this function was formerly EC:2.4.1.204.								molecular_function											owl:Class	
GO:1901121	biolink:NamedThing	tobramycin biosynthetic process	The chemical reactions and pathways resulting in the formation of tobramycin.	tmpzr1t_l9r_go_relaxed.owl	tobramycin formation|tobramycin biosynthesis|tobramycin anabolism|tobramycin synthesis							yaf	2012-07-11T03:15:51Z					biological_process											owl:Class	
GO:0010128	biolink:NamedThing	benzoate catabolic process via CoA ligation	The chemical reactions and pathways resulting in the breakdown of benzoate, by its ligation to Coenzyme A to form benzoyl-CoA, which is then broken by an aerobic or anaerobic pathway.	tmpzr1t_l9r_go_relaxed.owl	anaerobic benzoate catabolic process|anaerobic benzoate breakdown|anaerobic benzoate degradation|anaerobic benzoate catabolism				MetaCyc:PWY-283									biological_process											owl:Class	
GO:0055055	biolink:NamedThing	D-glucose:proton symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: D-glucose + H+ = D-glucose + H+. Symporter activity enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported together in the same direction in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy. D-glucose is the dextrorotatory D-enantiomer of glucose.	tmpzr1t_l9r_go_relaxed.owl	D-glucose:hydrogen symporter activity													molecular_function											owl:Class	
GO:0043700	biolink:NamedThing	pterinosome	A tissue-specific, membrane-bounded cytoplasmic organelle within which pteridine pigments are synthesized and stored. Pterinosomes are synthesized in xanthophores and erythrophore cells and are yellow, orange or red in appearance.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0047845	biolink:NamedThing	deoxylimonate A-ring-lactonase activity	Catalysis of the reaction: deoxylimonoate + H(2)O = deoxylimononate D-ring-lactone + H(+).	tmpzr1t_l9r_go_relaxed.owl	deoxylimonate A-ring-lactonohydrolase activity				EC:3.1.1.46|KEGG_REACTION:R03803|MetaCyc:DEOXYLIMONATE-A-RING-LACTONASE-RXN|RHEA:14997									molecular_function											owl:Class	
GO:0097680	biolink:NamedThing	double-strand break repair via classical nonhomologous end joining	An instance of double-strand break repair via nonhomologous end joining that requires a number of factors important for V(D)J recombination, including the KU70/80 heterodimer (KU), XRCC4, ligase IV, and DNA-PKcs in mammals. It does not produce translocations (as opposed to the alternative nonhomologous end joining).	tmpzr1t_l9r_go_relaxed.owl	C-NHEJ|canonical nonhomologous end joining							pr	2014-12-17T15:15:18Z					biological_process											owl:Class	
GO:0043822	biolink:NamedThing	ribonuclease M5 activity	Catalysis of the endonucleolytic cleavage of RNA, removing 21 and 42 nucleotides, respectively, from the 5'- and 3'-termini of a 5S-rRNA precursor.	tmpzr1t_l9r_go_relaxed.owl	RNase M5 activity|5S ribosomal maturation nuclease activity|5S ribosomal RNA maturation endonuclease activity				MetaCyc:3.1.26.8-RXN|EC:3.1.26.8									molecular_function											owl:Class	
GO:0010210	biolink:NamedThing	IAA-Phe conjugate hydrolase activity	Catalysis of the reaction: indole-3-acetyl-phenylalanine + H2O = indole-3-acetate + phenylalanine.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0010178	biolink:NamedThing	IAA-amino acid conjugate hydrolase activity	Catalysis of the cleavage of the amide bond between IAA (auxin) and the conjugated amino acid.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0036183	biolink:NamedThing	asperthecin catabolic process	The chemical reactions and pathways resulting in the breakdown of asperthecin, an anthraquinone pigment obtained from the mould Aspergillus nidulans.	tmpzr1t_l9r_go_relaxed.owl	asperthecin catabolism|asperthecin degradation|asperthecin breakdown							bf	2012-04-16T11:36:38Z					biological_process											owl:Class	
GO:0047099	biolink:NamedThing	CDP-4-dehydro-6-deoxyglucose reductase activity	Catalysis of the reaction: H2O + NAD(P)+ + CDP-4-dehydro-3,6-dideoxy-D-glucose = NAD(P)H + CDP-4-dehydro-6-deoxy-D-glucose.	tmpzr1t_l9r_go_relaxed.owl	CDP-4-dehydro-3,6-dideoxy-D-glucose:NAD(P)+ 3-oxidoreductase activity|NAD(P)H:CDP-4-keto-6-deoxy-D-glucose oxidoreductase activity|CDP-4-keto-6-deoxyglucose reductase activity|cytidine diphosphate 4-keto-6-deoxy-D-glucose-3-dehydrogenase activity|cytidine diphospho-4-keto-6-deoxy-D-glucose reductase activity|CDP-4-keto-6-deoxy-D-glucose-3-dehydrogenase system activity|CDP-4-keto-deoxy-glucose reductase activity				MetaCyc:1.17.1.1-RXN|EC:1.17.1.1									molecular_function											owl:Class	
GO:0043031	biolink:NamedThing	negative regulation of macrophage activation	Any process that stops, prevents, or reduces the frequency, rate or extent of macrophage activation.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of macrophage polarization|down regulation of macrophage activation|down-regulation of macrophage activation|inhibition of macrophage activation|downregulation of macrophage activation													biological_process											owl:Class	
GO:0047408	biolink:NamedThing	alkenylglycerophosphocholine hydrolase activity	Catalysis of the reaction: H2O + 1-(1-alkenyl)-sn-glycero-3-phosphocholine = L-1-glycero-3-phosphocholine + an aldehyde.	tmpzr1t_l9r_go_relaxed.owl	lysoplasmalogenase activity|1-(1-alkenyl)-sn-glycero-3-phosphocholine aldehydohydrolase activity				EC:3.3.2.2|RHEA:22544|MetaCyc:3.3.2.2-RXN									molecular_function											owl:Class	
GO:0035802	biolink:NamedThing	adrenal cortex formation	The process that gives rise to the adrenal cortex. This process pertains to the initial formation of a structure from unspecified parts. The adrenogonadal primordium from which the adrenal cortex is formed derives from a condensation of coelomic epithelial cells (the urogenital ridge; the same structure from which gonads and kidney also originate).	tmpzr1t_l9r_go_relaxed.owl	adrenal gland cortex formation							bf	2011-04-18T10:26:49Z					biological_process											owl:Class	
GO:0030749	biolink:NamedThing	loganate O-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + loganate = S-adenosyl-L-homocysteine + loganin.	tmpzr1t_l9r_go_relaxed.owl	S-adenosyl-L-methionine:loganic acid methyltransferase activity|loganate methyltransferase activity|S-adenosyl-L-methionine:loganate 11-O-methyltransferase activity				MetaCyc:LOGANATE-O-METHYLTRANSFERASE-RXN|EC:2.1.1.50|RHEA:12508									molecular_function											owl:Class	
GO:0102764	biolink:NamedThing	6-deoxotyphasterol C-23 hydroxylase activity	Catalysis of the reaction: 6-deoxotyphasterol + O2 + a reduced electron acceptor = 6-deoxocastasterone + H2O + an oxidized electron acceptor.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-777									molecular_function											owl:Class	
GO:0048293	biolink:NamedThing	regulation of isotype switching to IgE isotypes	Any process that modulates the frequency, rate or extent of isotype switching to IgE isotypes.	tmpzr1t_l9r_go_relaxed.owl	regulation of class switch recombination to IgE isotypes|regulation of isotype switch recombination to IgE isotypes|regulation of class switching to IgE isotypes													biological_process											owl:Class	
GO:1903833	biolink:NamedThing	positive regulation of cellular response to amino acid starvation	Any process that activates or increases the frequency, rate or extent of cellular response to amino acid starvation.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of cellular response to amino acid starvation|up regulation of cellular response to amino acid starvation|upregulation of cellular response to amino acid starvation|activation of cellular response to amino acid starvation							rn	2015-01-21T18:44:37Z					biological_process											owl:Class	
GO:0110108	biolink:NamedThing	positive regulation of imaginal disc-derived wing vein specification	Any process that activates or increases the frequency, rate or extent of imaginal disc-derived wing vein specification.	tmpzr1t_l9r_go_relaxed.owl								kmv	2018-07-05T13:52:31Z					biological_process											owl:Class	
GO:0045756	biolink:NamedThing	positive regulation of initiation of acetate catabolic process by acetate	Any process that activates or increases the frequency, rate or extent of the activation, by acetate, of the chemical reactions and pathways resulting in the breakdown of acetate.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of initiation of acetate breakdown by acetate|positive regulation of initiation of acetate degradation by acetate|up regulation of initiation of acetate catabolic process by acetate|stimulation of initiation of acetate catabolic process by acetate|activation of initiation of acetate catabolic process by acetate|upregulation of initiation of acetate catabolic process by acetate|up-regulation of initiation of acetate catabolic process by acetate													biological_process											owl:Class	
GO:0004526	biolink:NamedThing	ribonuclease P activity	Catalysis of the endonucleolytic cleavage of RNA, removing 5' extra nucleotides from tRNA precursor.	tmpzr1t_l9r_go_relaxed.owl	RNase P|tRNA 5' leader endonuclease activity				MetaCyc:3.1.26.5-RXN|EC:3.1.26.5|Wikipedia:RNase_P|Reactome:R-HSA-5696810									molecular_function											owl:Class	
GO:0010618	biolink:NamedThing	aerenchyma formation	The process that gives rise to aerenchyma, parenchyma tissue containing particularly large intercellular spaces of schizogenous or lysigenous origin. This process pertains to the initial formation of a structure from unspecified parts.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0045722	biolink:NamedThing	positive regulation of gluconeogenesis	Any process that activates or increases the frequency, rate or extent of gluconeogenesis.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of gluconeogenesis|upregulation of gluconeogenesis|up regulation of gluconeogenesis|stimulation of gluconeogenesis|activation of gluconeogenesis													biological_process											owl:Class	
GO:0047895	biolink:NamedThing	formaldehyde dismutase activity	Catalysis of the reaction: 2 formaldehyde + H2O = methanol + formate.	tmpzr1t_l9r_go_relaxed.owl	nicotinoprotein aldehyde dismutase|aldehyde dismutase activity|cannizzanase activity|formaldehyde:formaldehyde oxidoreductase activity				MetaCyc:FORMALDEHYDE-DISMUTASE-RXN|EC:1.2.98.1|RHEA:19221									molecular_function											owl:Class	
GO:0035650	biolink:NamedThing	AP-1 adaptor complex binding	Binding to an AP-1 adaptor complex. The AP-1 adaptor complex is a heterotetrameric AP-type membrane coat adaptor complex that consists of beta1, gamma, mu1 and sigma1 subunits and links clathrin to the membrane surface of a vesicle. In at least humans, the AP-1 complex can be heterogeneric due to the existence of multiple subunit isoforms encoded by different genes (gamma1 and gamma2, mu1A and mu1B, and sigma1A, sigma1B and sigma1C).	tmpzr1t_l9r_go_relaxed.owl								bf	2011-01-25T10:58:52Z					molecular_function											owl:Class	
GO:0061594	biolink:NamedThing	6-deoxy-6-sulfofructose kinase activity	Catalysis of the reaction 6-deoxy-6-sulfofructose + ATP = 6-deoxy-6-sulfofructose-1-phosphate + ADP.	tmpzr1t_l9r_go_relaxed.owl					RHEA:40443|MetaCyc:RXN-15297|EC:2.7.1.184			dph	2014-02-10T09:59:26Z					molecular_function											owl:Class	
GO:0070799	biolink:NamedThing	regulation of conidiophore stalk development	Any process that modulates the frequency, rate or extent of conidiophore stalk development, a process that leads to the formation of a conidiophore stalk. The conidiophore stalk is part of a specialized hypha that extends aerially from the growth substrate and supports structures from which conidia, or asexual spores, develop.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-07-08T04:03:40Z					biological_process											owl:Class	
GO:0003104	biolink:NamedThing	positive regulation of glomerular filtration	Any process that activates or increases the frequency, rate or extent of glomerular filtration. Glomerular filtration is the processs whereby blood is filtered by the glomerulus into the renal tubule.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0042332	biolink:NamedThing	gravitaxis	The directed movement of a motile cell or organism in response to gravity.	tmpzr1t_l9r_go_relaxed.owl	taxis in response to gravitational stimulus|gravitactic behavior|taxis in response to gravity|geotaxis|geotactic behavior|geotactic behaviour|gravitactic behaviour											GO:0048062		biological_process											owl:Class	
GO:0033104	biolink:NamedThing	type VI protein secretion system complex	A complex of proteins that permits the transfer of proteins into the extracellular milieu or directly into host cells via the type VI secretion system. Proteins secreted by this complex do not require an N-terminal signal sequence.	tmpzr1t_l9r_go_relaxed.owl	T6SS complex													cellular_component											owl:Class	
GO:0035464	biolink:NamedThing	regulation of transforming growth factor receptor beta signaling pathway involved in determination of left/right asymmetry	Any process that modulates the frequency, rate or extent of activity of any TGF-beta receptor signaling pathway that is involved in the determination of organismal asymmetry with regard to its left and right halves.	tmpzr1t_l9r_go_relaxed.owl	regulation of TGF-beta receptor signalling pathway involved in determination of left/right asymmetry|regulation of TGFbeta receptor signalling pathway involved in determination of left/right asymmetry|regulation of transforming growth factor beta receptor signalling pathway involved in determination of left/right asymmetry|regulation of TGFbeta receptor signaling pathway involved in determination of left/right asymmetry|regulation of TGF-beta receptor signaling pathway involved in determination of left/right asymmetry							bf	2010-04-19T01:31:56Z					biological_process											owl:Class	
GO:0018769	biolink:NamedThing	2-hydroxy-6-oxoocta-2,4-dienoate hydrolase activity	Catalysis of the reaction: 2-hydroxy-6-oxoocta-2,4-dienoate + H2O = H+ + propanoate + cis-2-hydroxypenta-2,4-dienoate.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0311									molecular_function											owl:Class	
GO:0060357	biolink:NamedThing	regulation of leucine import	Any process that modulates the rate, frequency or extent of leucine import. Leucine import is the directed movement of leucine into a cell or organelle.	tmpzr1t_l9r_go_relaxed.owl	regulation of L-leucine import|regulation of leucine uptake|regulation of L-leucine uptake													biological_process											owl:Class	
GO:0044818	biolink:NamedThing	mitotic G2/M transition checkpoint	A cell cycle checkpoint that detects and negatively regulates progression from G2 to M phase as part of a mitotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl								jl	2013-11-19T14:20:00Z					biological_process											owl:Class	
GO:1904842	biolink:NamedThing	response to nitroglycerin	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitroglycerin stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to trinitroglycerin|response to nitroglycerine|response to trinitroglycerol|response to nitroglycerol							sl	2015-12-07T18:30:47Z					biological_process											owl:Class	
GO:0098746	biolink:NamedThing	fast, calcium ion-dependent exocytosis of neurotransmitter	The fast, initial phase of calcium ion-induced neurotransmitter release, via exocytosis, into the synaptic cleft. This depends on low affinity calcium sensors and typically begins a fraction of a millisecond after Ca2+ influx, and decays rapidly (1-10ms) with a decay constant of around 5-10ms. The underlying molecular mechanisms of this process are distinct from those of the later, slow phase of release.	tmpzr1t_l9r_go_relaxed.owl	synchronous, calcium ion-dependent exocytosis of neurotransmitter													biological_process											owl:Class	
GO:0102785	biolink:NamedThing	violaxanthin oxygenase activity	Catalysis of the reaction: violaxanthin + 2 O2 = 2 5,6-epoxy-3-hydroxy-9-apo-beta-caroten-9-one + 4,9-dimethyldodeca-2,4,6,8,10-pentaenedial.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-7886									molecular_function											owl:Class	
GO:0009135	biolink:NamedThing	purine nucleoside diphosphate metabolic process	The chemical reactions and pathways involving purine nucleoside diphosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with diphosphate on the sugar.	tmpzr1t_l9r_go_relaxed.owl	purine nucleoside diphosphate metabolism													biological_process											owl:Class	
GO:0046296	biolink:NamedThing	glycolate catabolic process	The chemical reactions and pathways resulting in the breakdown of glycolate, the anion of hydroxyethanoic acid (glycolic acid).	tmpzr1t_l9r_go_relaxed.owl	glycolate catabolism|glycolate breakdown|glycolate degradation													biological_process											owl:Class	
GO:0047541	biolink:NamedThing	2-furoate-CoA ligase activity	Catalysis of the reaction: 2-furoate + ATP + CoA = 2-furoyl-CoA + AMP + diphosphate + H(+).	tmpzr1t_l9r_go_relaxed.owl	2-furoyl coenzyme A synthetase activity|2-furoate:CoA ligase (AMP-forming)				MetaCyc:2-FUROATE--COA-LIGASE-RXN|RHEA:19269|EC:6.2.1.31|KEGG_REACTION:R02986									molecular_function											owl:Class	
GO:0098913	biolink:NamedThing	membrane depolarization during ventricular cardiac muscle cell action potential	The process in which ventricular cardiac muscle cell membrane potential changes in the depolarizing direction from the negative resting potential towards the positive membrane potential that will be the peak of the action potential.	tmpzr1t_l9r_go_relaxed.owl	electrocardiogram QRS complex|ventricular depolarization													biological_process											owl:Class	
GO:0051723	biolink:NamedThing	protein methylesterase activity	Catalysis of the reaction: protein amino acid methyl ester + H2O = protein amino acid + methanol.	tmpzr1t_l9r_go_relaxed.owl	protein carboxyl methylesterase activity|PME activity|protein carboxylic ester hydrolase activity|protein methyl-esterase activity				Reactome:R-HSA-5367022									molecular_function											owl:Class	
GO:0070340	biolink:NamedThing	detection of bacterial lipopeptide	The series of events in which a bacterial lipopeptide stimulus is received by a cell and converted into a molecular signal.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0090600	biolink:NamedThing	alpha-1,3-glucosidase activity	Catalysis of the hydrolysis of terminal, non-reducing alpha-(1->3)-linked alpha-D-glucose residues with release of alpha-D-glucose.	tmpzr1t_l9r_go_relaxed.owl								tb	2014-08-22T15:00:45Z					molecular_function											owl:Class	
GO:0042039	biolink:NamedThing	vanadium incorporation into metallo-sulfur cluster	The incorporation of vanadium a metallo-sulfur cluster such as VFe(7-8)S(n).	tmpzr1t_l9r_go_relaxed.owl	vanadium incorporation into metallo-sulphur cluster													biological_process											owl:Class	
GO:0038171	biolink:NamedThing	cannabinoid signaling pathway	The series of molecular signals generated as a consequence of a cannabinoid binding to a cell surface receptor. The pathway proceeds with the receptor transmitting the signal to a heterotrimeric G-protein complex and ends with regulation of a downstream cellular process, e.g. transcription. Cannabinoids are a class of diverse chemical compounds that include the endocannabinoids and the phytocannabinoids.	tmpzr1t_l9r_go_relaxed.owl	cannabinoid receptor signaling pathway|cannabinoid-mediated signaling pathway|cannabinoid-activated signaling pathway							bf	2012-06-12T10:47:53Z					biological_process											owl:Class	
GO:0003417	biolink:NamedThing	growth plate cartilage development	The process whose specific outcome is the progression of the cartilage that will provide a scaffold for mineralization of endochondral bones as they elongate or grow.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-12-22T08:57:42Z					biological_process											owl:Class	
GO:0035356	biolink:NamedThing	cellular triglyceride homeostasis	Any process involved in the maintenance of an internal steady state of triglyceride within a cell or between a cell and its external environment.	tmpzr1t_l9r_go_relaxed.owl								bf	2010-03-05T10:28:11Z					biological_process											owl:Class	
GO:0052793	biolink:NamedThing	pectin acetylesterase activity	Catalysis of the reaction: pectin + H2O = pectate + acetate. This reaction is the hydrolysis of acetyl esters of pectin, producing pectate, partially esterified pectin.	tmpzr1t_l9r_go_relaxed.owl								ai	2011-10-05T05:17:21Z					molecular_function											owl:Class	
GO:0043445	biolink:NamedThing	acetone biosynthetic process	The chemical reactions and pathways resulting in the formation of acetone, propan-2-one.	tmpzr1t_l9r_go_relaxed.owl	propan-2-one biosynthetic process|acetone anabolism|dimethyl ketone biosynthesis|2-propanone biosynthetic process|acetone synthesis|acetone biosynthesis|acetone formation|propan-2-one biosynthesis|2-propanone biosynthesis|dimethyl ketone biosynthetic process													biological_process											owl:Class	
GO:0005998	biolink:NamedThing	xylulose catabolic process	The chemical reactions and pathways resulting in the breakdown of xylulose, the ketopentose threo-2-pentulose.	tmpzr1t_l9r_go_relaxed.owl	xylulose catabolism|xylulose degradation|xylulose breakdown				MetaCyc:XYLCAT-PWY									biological_process											owl:Class	
GO:0035074	biolink:NamedThing	pupation	The act of becoming a pupa, a resting stage in the life cycle of organisms with complete metamorphosis. This event marks the end of the prepupal period and the beginning of the pupal period.	tmpzr1t_l9r_go_relaxed.owl	prepupal-pupal transition|head eversion				Wikipedia:Pupa									biological_process											owl:Class	
GO:0090451	biolink:NamedThing	cotyledon boundary formation	The process in which boundaries between a cotyledon and the surrounding tissue are established and maintained.	tmpzr1t_l9r_go_relaxed.owl								tb	2012-09-19T10:26:54Z					biological_process											owl:Class	
GO:0019008	biolink:NamedThing	molybdopterin synthase complex	A protein complex that possesses molybdopterin synthase activity. In E. coli, the complex is a heterotetramer consisting of two MoaD and two MoaE subunits.	tmpzr1t_l9r_go_relaxed.owl	molybdopterin converting factor complex											GO:0019009		cellular_component											owl:Class	
GO:0033925	biolink:NamedThing	mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase activity	Catalysis of the endohydrolysis of the N,N'-diacetylchitobiosyl unit in high-mannose glycopeptides and glycoproteins containing the -[Man(GlcNAc)2]Asn-structure. One N-acetyl-D-glucosamine residue remains attached to the protein; the rest of the oligosaccharide is released intact.	tmpzr1t_l9r_go_relaxed.owl	endo-beta-N-acetylglucosaminidase F activity|endo-beta-N-acetylglucosaminidase L activity|endoglycosidase H activity|endo-beta-(1->4)-N-acetylglucosaminidase activity|glycopeptide-D-mannosyl-N4-(N-acetyl-D-glucosaminyl)2-asparagine 1,4-N-acetyl-beta-glucosaminohydrolase activity|N,N'-diacetylchitobiosyl beta-N-acetylglucosaminidase activity|endo-N-acetyl-beta-glucosaminidase activity|di-N-acetylchitobiosyl beta-N-acetylglucosaminidase activity|endo-beta-acetylglucosaminidase activity|endo-beta-N-acetylglucosaminidase D activity|mannosyl-glycoprotein 1,4-N-acetamidodeoxy-beta-D-glycohydrolase activity|glycopeptide-D-mannosyl-4-N-(N-acetyl-D-glucosaminyl)2-asparagine 1,4-N-acetyl-beta-glucosaminohydrolase activity|endo-beta-N-acetylglucosaminidase H activity|endoglycosidase S activity|mannosyl-glycoprotein endo-beta-N-acetylglucosamidase activity|endo-beta-N-acetylglucosaminidase activity|endo-N-acetyl-beta-D-glucosaminidase activity				MetaCyc:3.2.1.96-RXN|EC:3.2.1.96|Reactome:R-HSA-8853379									molecular_function											owl:Class	
GO:1901060	biolink:NamedThing	p-hydroxyphenyl lignin biosynthetic process	The chemical reactions and pathways resulting in the formation of p-hydroxyphenyl lignin.	tmpzr1t_l9r_go_relaxed.owl	p-hydroxyphenyl lignin anabolism|p-hydroxyphenyl lignin synthesis|H-lignin biosynthetic process|p-hydroxyphenyl lignin formation|p-hydroxyphenyl lignin biosynthesis							tt	2012-06-29T02:42:36Z					biological_process											owl:Class	
GO:0030070	biolink:NamedThing	insulin processing	The formation of mature insulin by proteolysis of the precursor preproinsulin. The signal sequence is first cleaved from preproinsulin to form proinsulin; proinsulin is then cleaved to release the C peptide, leaving the A and B chains of mature insulin linked by disulfide bridges.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1901142	biolink:NamedThing	insulin metabolic process	The chemical reactions and pathways involving insulin.	tmpzr1t_l9r_go_relaxed.owl	insulin metabolism							pm	2012-07-13T12:32:40Z					biological_process											owl:Class	
GO:0000033	biolink:NamedThing	alpha-1,3-mannosyltransferase activity	Catalysis of the transfer of a mannose residue to an oligosaccharide, forming an alpha-(1->3) linkage.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-4549368|Reactome:R-HSA-446208|Reactome:R-HSA-446188|Reactome:R-HSA-4720473									molecular_function											owl:Class	
GO:0048864	biolink:NamedThing	stem cell development	The process whose specific outcome is the progression of the stem cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to its specific fate.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0047843	biolink:NamedThing	dehydrogluconate dehydrogenase activity	Catalysis of the reaction: 2-dehydro-D-gluconate + A = 2,5-didehydro-D-gluconate + AH(2).	tmpzr1t_l9r_go_relaxed.owl	2-dehydro-D-gluconate:acceptor 2-oxidoreductase activity|ketogluconate dehydrogenase activity|2-keto-D-gluconate dehydrogenase activity|2-oxogluconate dehydrogenase activity|alpha-ketogluconate dehydrogenase activity				MetaCyc:DEHYDROGLUCONATE-DEHYDROGENASE-RXN|KEGG_REACTION:R07153|EC:1.1.99.4|RHEA:12368									molecular_function											owl:Class	
GO:0007618	biolink:NamedThing	mating	The pairwise union of individuals for the purpose of sexual reproduction, ultimately resulting in the formation of zygotes.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0062058	biolink:NamedThing	transcription factor TFIIH holo complex binding	Binding to a transcription factor TFIIH holo complex.	tmpzr1t_l9r_go_relaxed.owl								dph	2018-08-31T13:44:17Z					molecular_function											owl:Class	
GO:2001233	biolink:NamedThing	regulation of apoptotic signaling pathway	Any process that modulates the frequency, rate or extent of apoptotic signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	regulation of apoptotic signalling pathway							pr	2011-11-24T01:20:49Z					biological_process											owl:Class	
GO:0038088	biolink:NamedThing	VEGF-activated platelet-derived growth factor receptor-beta signaling pathway	A series of molecular signals initiated by the binding of a vascular endothelial growth factor (VEGF) to a beta-type platelet-derived growth factor receptor (PDGFR) on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.	tmpzr1t_l9r_go_relaxed.owl	VEGF/PDGFRbeta signaling pathway|VEGF-activated PDGFRbeta signalling pathway|VEGF-activated platelet-derived growth factor receptor-beta signalling pathway|vascular endothelial growth factor-activated platelet-derived growth factor receptor-beta signaling pathway|VEGF-A/PDGFRbeta signaling							bf	2012-02-01T03:10:16Z					biological_process											owl:Class	
GO:0102223	biolink:NamedThing	4,4'-diapophytoene desaturase activity	Catalysis of the reaction: 4 H+ + 15-cis-4,4'-diapophytoene + 4 FAD <=> 4,4'-diapolycopene + 4 FADH2.	tmpzr1t_l9r_go_relaxed.owl					RHEA:31391|EC:1.3.8.2|MetaCyc:RXN-12224									molecular_function											owl:Class	
GO:0034935	biolink:NamedThing	tetrachlorobenzene dioxygenase activity	Catalysis of the reaction: 2,4-dichlorotoluene + NADH + H+ + O2 = 4,6-dichloro-3-methyl-cis-1,2-dihydroxycyclohexa-3,5-diene + NAD+.	tmpzr1t_l9r_go_relaxed.owl					EC:1.13.11.-|UM-BBD_reactionID:r0957									molecular_function											owl:Class	
GO:0071344	biolink:NamedThing	diphosphate metabolic process	The chemical reactions and pathways involving diphosphate, the anion or salt of diphosphoric acid.	tmpzr1t_l9r_go_relaxed.owl	pyrophosphate metabolism							mah	2009-12-11T01:43:41Z					biological_process											owl:Class	
GO:0033930	biolink:NamedThing	keratan-sulfate endo-1,4-beta-galactosidase activity	Catalysis of the endohydrolysis of (1->4)-beta-D-galactosidic linkages in keratan sulfate.	tmpzr1t_l9r_go_relaxed.owl	keratan sulfate endogalactosidase activity|keratan-sulfate 1,4-beta-D-galactanohydrolase activity|keratanase activity|endo-beta-galactosidase activity				MetaCyc:3.2.1.103-RXN|EC:3.2.1.103									molecular_function											owl:Class	
GO:0010179	biolink:NamedThing	IAA-Ala conjugate hydrolase activity	Catalysis of the reaction: indole-3-acetyl-alanine + H2O = indole-3-acetate + L-alanine.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-2981									molecular_function											owl:Class	
GO:0019770	biolink:NamedThing	IgG receptor activity	Combining with an immunoglobulin of an IgG isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0098038	biolink:NamedThing	non-replicative transposition, DNA-mediated	Process by which a transposable element is excised from the donor site and integrated at the target site without replication of the element. Also referred to as cut-and-paste transposition.	tmpzr1t_l9r_go_relaxed.owl	cut-and-paste transposition							bm	2012-07-20T16:47:50Z					biological_process											owl:Class	
GO:0046783	biolink:NamedThing	modification by virus of host polysomes	Any viral process that interferes with and inhibits the assembly and function of polysomes.	tmpzr1t_l9r_go_relaxed.owl	viral perturbation of polysomes					See also the cellular component term 'polysome ; GO:0005844'.								biological_process											owl:Class	
GO:0034217	biolink:NamedThing	ascospore wall chitin biosynthetic process	The chemical reactions and pathways resulting in the formation of ascospore wall chitin, a linear polysaccharide consisting of P-1,4-linked N-acetyl-D-glucosamine residues, found in the walls of ascospores.	tmpzr1t_l9r_go_relaxed.owl	ascospore wall chitin formation|ascospore wall chitin synthesis|ascospore wall chitin anabolism|ascospore wall chitin biosynthesis													biological_process											owl:Class	
GO:1905229	biolink:NamedThing	cellular response to thyrotropin-releasing hormone	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a thyrotropin-releasing hormone (TRH) stimulus. TRH increases the secretion of thyroid-stimulating hormone by the anterior pituitary.	tmpzr1t_l9r_go_relaxed.owl	cellular response to protirelin|cellular response to TRH							sl	2016-06-07T16:14:10Z					biological_process											owl:Class	
GO:0031931	biolink:NamedThing	TORC1 complex	A protein complex that contains at least TOR (target of rapamycin) and Raptor (regulatory-associated protein of TOR), or orthologs of, in complex with other signaling components. Mediates the phosphorylation and activation of S6K. In Saccharomyces, the complex contains Kog1p, Lst8p, Tco89p, and either Tor1p or Tor2p.	tmpzr1t_l9r_go_relaxed.owl	nutrient sensitive complex|TORC1|mTORC1|TOR complex 1|TORC 1 complex|dTOR/dRaptor complex|dTORC1|rapamycin and nutrient-sensitive TOR complex				Wikipedia:MTORC1									cellular_component											owl:Class	
GO:2000767	biolink:NamedThing	positive regulation of cytoplasmic translation	Any process that activates or increases the frequency, rate or extent of cytoplasmic translation.	tmpzr1t_l9r_go_relaxed.owl								vw	2011-06-20T10:39:26Z					biological_process											owl:Class	
GO:0106267	biolink:NamedThing	3,5 dichloro-THPH synthase activity	Catalysis of the reaction: (3-chloro-2,4,6-trihydroxyphenyl)hexan-1-one + chloride + FADH2 + O2 = (3,5-dichloro-2,4,6-trihydroxyphenyl)hexan-1-one + FAD + 2 H2O.	tmpzr1t_l9r_go_relaxed.owl					RHEA:64360			hjd	2020-06-02T18:16:23Z					molecular_function											owl:Class	
GO:0043230	biolink:NamedThing	extracellular organelle	Organized structure of distinctive morphology and function, occurring outside the cell. Includes, for example, extracellular membrane vesicles (EMVs) and the cellulosomes of anaerobic bacteria and fungi.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0033461	biolink:NamedThing	GGU codon-amino acid adaptor activity	A triplet codon-amino acid adaptor activity that recognizes a GGU codon.	tmpzr1t_l9r_go_relaxed.owl	glycine tRNA|GGT codon-amino acid adaptor activity					Note that in the standard genetic code, GGT codes for glycine.								molecular_function											owl:Class	
GO:1905265	biolink:NamedThing	blasticidin S catabolic process	The chemical reactions and pathways resulting in the breakdown of blasticidin S.	tmpzr1t_l9r_go_relaxed.owl	blasticidin S breakdown|blasticidin S degradation|blasticidin S catabolism							pr	2016-06-14T12:47:13Z					biological_process											owl:Class	
GO:0003044	biolink:NamedThing	regulation of systemic arterial blood pressure mediated by a chemical signal	The regulation of blood pressure mediated by biochemical signaling: hormonal, autocrine or paracrine.	tmpzr1t_l9r_go_relaxed.owl	blood pressure regulation mediated by a chemical signal													biological_process											owl:Class	
GO:1905197	biolink:NamedThing	endocannabinoid signaling pathway involved in retrograde trans-synaptic signaling	Any endocannabinoid signaling pathway that is involved in retrograde trans-synaptic signaling by endocannabinoid.	tmpzr1t_l9r_go_relaxed.owl	endocannabinoid signalling pathway involved in retrograde trans-synaptic signaling by endocannabinoid							dos	2016-05-12T14:29:38Z					biological_process											owl:Class	
GO:0007307	biolink:NamedThing	eggshell chorion gene amplification	Amplification by up to 60-fold of the loci containing the chorion gene clusters. Amplification is necessary for the rapid synthesis of chorion proteins by the follicle cells, and occurs by repeated firing of one or more origins located within each gene cluster.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0009035	biolink:NamedThing	type I site-specific deoxyribonuclease activity	Catalysis of the endonucleolytic cleavage of DNA to give random double-stranded fragments with terminal 5' or 3' protrusions, driven by ATP hydrolysis. Cleavage is dependent on the presence in the DNA of a specific recognition site. Cleavage may occur hundreds or thousands of base pairs away from the recognition site due to translocation of DNA.	tmpzr1t_l9r_go_relaxed.owl	adenosine triphosphate-dependent deoxyribonuclease activity|type I restriction enzyme activity|ATP-dependent DNase activity|deoxyribonuclease (adenosine triphosphate-hydrolyzing)|deoxyribonuclease (ATP- and S-adenosyl-L-methionine-dependent)	https://github.com/geneontology/go-ontology/issues/21612			EC:3.1.21.3|MetaCyc:3.1.21.3-RXN									molecular_function											owl:Class	
GO:0003299	biolink:NamedThing	muscle hypertrophy in response to stress	The enlargement or overgrowth of all or part of a muscle organ or tissue due to an increase in the size of its muscle cells as a result of a disturbance in organismal or cellular homeostasis.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-10-22T09:26:10Z					biological_process											owl:Class	
GO:0016595	biolink:NamedThing	glutamate binding	Binding to glutamate, the anion of 2-aminopentanedioic acid.	tmpzr1t_l9r_go_relaxed.owl	glutamic acid binding													molecular_function											owl:Class	
GO:0051384	biolink:NamedThing	response to glucocorticoid	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucocorticoid stimulus. Glucocorticoids are hormonal C21 corticosteroids synthesized from cholesterol with the ability to bind with the cortisol receptor and trigger similar effects. Glucocorticoids act primarily on carbohydrate and protein metabolism, and have anti-inflammatory effects.	tmpzr1t_l9r_go_relaxed.owl	response to glucocorticoid stimulus													biological_process											owl:Class	
GO:0070349	biolink:NamedThing	positive regulation of brown fat cell proliferation	Any process that activates or increases the rate or extent of brown fat cell proliferation.	tmpzr1t_l9r_go_relaxed.owl	up regulation of brown fat cell proliferation|positive regulation of brown adipocyte proliferation|activation of brown fat cell proliferation|stimulation of brown fat cell proliferation|positive regulation of brown adipose cell proliferation|upregulation of brown fat cell proliferation|up-regulation of brown fat cell proliferation													biological_process											owl:Class	
GO:0035024	biolink:NamedThing	negative regulation of Rho protein signal transduction	Any process that stops, prevents, or reduces the frequency, rate or extent of Rho protein signal transduction.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of Rho protein signal transduction|downregulation of Rho protein signal transduction|down regulation of Rho protein signal transduction|inhibition of Rho protein signal transduction													biological_process											owl:Class	
GO:0062130	biolink:NamedThing	adhesive extracellular matrix	A extracellular matrix which attaches an organism to a substrate.	tmpzr1t_l9r_go_relaxed.owl	puparial glue							dph	2019-06-21T12:35:06Z					cellular_component											owl:Class	
GO:0009703	biolink:NamedThing	nitrate reductase (NADH) activity	Catalysis of the reaction: nitrite + NAD+ + H2O = nitrate + NADH + H+.	tmpzr1t_l9r_go_relaxed.owl	NADH:nitrate oxidoreductase activity|nitrate reductase (NADH2)|nitrite:NAD+ oxidoreductase activity|NADH-nitrate reductase activity|NADH-dependent nitrate reductase activity|assimilatory NADH: nitrate reductase activity|assimilatory NADH:nitrate reductase activity|NADH:nitrate reductase activity|nitrate reductase (NADH(2)) activity|assimilatory nitrate reductase activity				EC:1.7.1.1|MetaCyc:NITRATE-REDUCTASE-NADH-RXN|RHEA:17913	Note that this function was formerly EC:1.6.6.1.								molecular_function											owl:Class	
GO:0019518	biolink:NamedThing	L-threonine catabolic process to glycine	The chemical reactions and pathways resulting in the breakdown of L-threonine (the L-enantiomer of 2-amino-3-hydroxybutyric acid) to form to form 2-amino-3-oxobutanoate, which is subsequently converted to glycine.	tmpzr1t_l9r_go_relaxed.owl	L-threonine catabolic process to pyruvate|L-threonine degradation to glycine|L-threonine catabolism to glycine|threonine catabolic process to glycine|L-threonine breakdown to glycine				MetaCyc:THREONINE-DEG2-PWY									biological_process											owl:Class	
GO:0071282	biolink:NamedThing	cellular response to iron(II) ion	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iron(II) ion stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to iron(II)							mah	2009-12-10T03:57:49Z					biological_process											owl:Class	
GO:2001312	biolink:NamedThing	lysobisphosphatidic acid biosynthetic process	The chemical reactions and pathways resulting in the formation of a lysobisphosphatidic acid. A lysobisphosphatidic acid is a lysophosphatidic acid having the unusual property of a phosphodiester moiety linked to positions sn-1 and sn1' of glycerol; and two additional fatty acids esterified to the glycerol head group.	tmpzr1t_l9r_go_relaxed.owl	LBPA synthesis|bis(monoacylglycerol) hydrogen phosphate (BMP) biosynthetic process|lysobisphosphatidic acid biosynthesis|bis(monoacylglycerol) hydrogen phosphate biosynthetic process|bis(monoacylglycerol) hydrogen phosphate formation|lysobisphosphatidic acid formation|bis(monoacylglycerol) hydrogen phosphate (BMP) anabolism|bis(monoacylglycerol) hydrogen phosphate biosynthesis|LBPA biosynthesis|bis(monoacylglycerol) hydrogen phosphate anabolism|LBPA biosynthetic process|LBPA formation|bis(monoacylglycerol) hydrogen phosphate (BMP) synthesis|bis(monoacylglycerol) hydrogen phosphate (BMP) formation|bis(monoacylglycerol) hydrogen phosphate (BMP) biosynthesis|bis(monoacylglycerol) hydrogen phosphate synthesis|lysobisphosphatidic acid anabolism|LBPA anabolism|lysobisphosphatidic acid synthesis							bf	2012-03-16T09:31:31Z					biological_process											owl:Class	
GO:0031831	biolink:NamedThing	type 5B serotonin receptor binding	Binding to a type 5B serotonin receptor.	tmpzr1t_l9r_go_relaxed.owl	type 5B serotonin receptor ligand|5-hydroxytryptamine 5B receptor binding													molecular_function											owl:Class	
GO:0016150	biolink:NamedThing	translation release factor activity, codon nonspecific	A translation release factor that is not specific to particular codons; binds to guanine nucleotides.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0008079	biolink:NamedThing	translation termination factor activity	Functions in the termination of translation.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0046010	biolink:NamedThing	positive regulation of circadian sleep/wake cycle, non-REM sleep	Any process that activates or increases the duration or quality of non-rapid eye movement (NREM) sleep.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of circadian sleep/wake cycle, non-REM sleep|stimulation of circadian sleep/wake cycle, non-REM sleep|upregulation of circadian sleep/wake cycle, non-REM sleep|activation of circadian sleep/wake cycle, non-REM sleep|up regulation of circadian sleep/wake cycle, non-REM sleep|positive regulation of non-REM sleep													biological_process											owl:Class	
GO:0015773	biolink:NamedThing	raffinose transport	The directed movement of raffinose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Raffinose occurs in plants almost as commonly as sucrose and is present in cereal grains, cotton seeds, and many legumes. It is synthesized from sucrose by transfer of a galactopyranoside from myo-inositol.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0050451	biolink:NamedThing	CoA-disulfide reductase activity	Catalysis of the reaction: 2 CoA + NAD+ = CoA-disulfide + NADH + H+.	tmpzr1t_l9r_go_relaxed.owl	CoA:NAD+ oxidoreductase activity|CoADR activity|CoA-disulfide reductase (NADH) activity|coenzyme A disulfide reductase activity|NADH:CoA-disulfide oxidoreductase activity|CoA-disulfide reductase [NAD(P)H]|CoA-disulfide reductase (NADH2)|CoA-disulphide reductase activity|CoA:NAD(P)+ oxidoreductase activity|NADH2:CoA-disulfide oxidoreductase activity|CoA-disulfide reductase (NAD(P)H) activity				MetaCyc:COA-DISULFIDE-REDUCTASE-NADH-RXN|EC:1.8.1.14|RHEA:14705									molecular_function											owl:Class	
GO:0021613	biolink:NamedThing	facial nerve maturation	A developmental process, independent of morphogenetic (shape) change, that is required for the facial nerve to attain its fully functional state. This sensory and motor nerve supplies the muscles of facial expression and the expression and taste at the anterior two-thirds of the tongue. The principal branches are the superficial opthalmic, buccal, palatine and hyomandibular. The main trunk synapses within pterygopalatine ganglion in the parotid gland and this ganglion then gives of nerve branches which supply the lacrimal gland and the mucous secreting glands of the nasal and oral cavities.	tmpzr1t_l9r_go_relaxed.owl	CN VII maturation													biological_process											owl:Class	
GO:0000176	biolink:NamedThing	nuclear exosome (RNase complex)	A ribonuclease complex that has 3-prime to 5-prime processive and distributive hydrolytic exoribonuclease activity and endoribonuclease activity, producing 5-prime-phosphomonoesters. Participates in a multitude of cellular RNA processing and degradation events preventing nuclear export and/or translation of aberrant RNAs. Restricted to processing linear and circular single-stranded RNAs (ssRNA) only. RNAs with complex secondary structures may have to be unwound or pre-processed by co-factors prior to entering the complex, esp if the 3-prime end is structured.	tmpzr1t_l9r_go_relaxed.owl	eukaryotic exosome multienzyme ribonuclease complex|nuclear exosome multienzyme ribonuclease complex|nuclear exosome (ribonuclease complex)													cellular_component											owl:Class	
GO:0031393	biolink:NamedThing	negative regulation of prostaglandin biosynthetic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of prostaglandin.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of prostaglandin biosynthesis|downregulation of prostaglandin biosynthetic process|down-regulation of prostaglandin biosynthetic process|down regulation of prostaglandin biosynthetic process|negative regulation of prostaglandin formation|inhibition of prostaglandin biosynthetic process|negative regulation of prostaglandin anabolism|negative regulation of prostaglandin synthesis													biological_process											owl:Class	
GO:0050784	biolink:NamedThing	cocaine catabolic process	The chemical reactions and pathways resulting in the breakdown of cocaine, an alkaloid obtained from the dried leaves of the shrub Erythroxylon coca. It is a cerebral stimulant and narcotic.	tmpzr1t_l9r_go_relaxed.owl	cocaine catabolism|cocaine degradation|cocaine breakdown													biological_process											owl:Class	
GO:0071648	biolink:NamedThing	positive regulation of macrophage inflammatory protein-1 gamma production	Any process that activates or increases the frequency, rate, or extent of production of macrophage inflammatory protein-1 gamma.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of CCL9 production|positive regulation of chemokine (C-C motif) ligand 9 production|positive regulation of MIP-1g production							mah	2010-02-12T10:40:19Z					biological_process											owl:Class	
GO:0050119	biolink:NamedThing	N-acetylglucosamine deacetylase activity	Catalysis of the reaction: N-acetyl-D-glucosamine + H(2)O = D-glucosamine + acetate.	tmpzr1t_l9r_go_relaxed.owl	N-acetyl-D-glucosamine amidohydrolase activity|acetylaminodeoxyglucose acetylhydrolase activity|N-acetyl-D-glucosaminyl N-deacetylase activity				MetaCyc:N-ACETYLGLUCOSAMINE-DEACETYLASE-RXN|KEGG_REACTION:R01200|RHEA:20593|EC:3.5.1.33|Reactome:R-HSA-2022887									molecular_function											owl:Class	
GO:0036374	biolink:NamedThing	glutathione hydrolase activity	Catalysis of the reaction: glutathione + H2O = L-cysteinylglycine + L-glutamate.	tmpzr1t_l9r_go_relaxed.owl	gamma-glutamyltranspeptidase activity|glutathionase activity				Reactome:R-HSA-9026916|MetaCyc:RXN-12618|Reactome:R-HSA-5602984|Reactome:R-HSA-9026927|Reactome:R-HSA-9026757|Reactome:R-HSA-9026907|RHEA:28807|EC:3.4.19.13|Reactome:R-HSA-266046|Reactome:R-HSA-5433072|Reactome:R-HSA-9035966|Reactome:R-HSA-8943279|Reactome:R-HSA-1222712|Reactome:R-HSA-9026912|KEGG_REACTION:R00494			bf	2013-05-07T09:58:07Z					molecular_function											owl:Class	
GO:0097489	biolink:NamedThing	multivesicular body, internal vesicle lumen	The volume enclosed by the membrane of the multivesicular body internal vesicle.	tmpzr1t_l9r_go_relaxed.owl								pr	2013-07-08T20:38:36Z					cellular_component											owl:Class	
GO:0102487	biolink:NamedThing	dUTP phosphohydrolase activity	Catalysis of the reaction: dUTP + 2 H2O = dUMP + 2 hydrogenphosphate + 2 H+.	tmpzr1t_l9r_go_relaxed.owl					EC:3.6.1.5|MetaCyc:RXN-14199									molecular_function											owl:Class	
GO:0042038	biolink:NamedThing	peptidyl-histidine methylation, to form tele-methylhistidine	The methylation of peptidyl-L-histidine to form peptidyl-L-1'-methyl-L-histidine (otherwise known as tau-methylhistidine, tele-methylhistidine).	tmpzr1t_l9r_go_relaxed.owl	peptidyl-histidine tele-methylation				RESID:AA0317							GO:0042261		biological_process											owl:Class	
GO:0018021	biolink:NamedThing	peptidyl-histidine methylation	The methylation of peptidyl-L-histidine to form peptidyl-L-1'-methyl-L-histidine (otherwise known as tau-methylhistidine, tele-methylhistidine) or peptidyl-L-3'-methyl-L-histidine (otherwise known as pi-methylhistidine, pros-methylhistidine).	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0317|RESID:AA0073									biological_process											owl:Class	
GO:1904274	biolink:NamedThing	tricellular tight junction assembly	The aggregation, arrangement and bonding together of a set of components to form a tricellular tight junction.	tmpzr1t_l9r_go_relaxed.owl	tricellular tight junction formation							mr	2015-05-29T16:31:00Z					biological_process											owl:Class	
GO:0004461	biolink:NamedThing	lactose synthase activity	Catalysis of the reaction: UDP-galactose + D-glucose = UDP + lactose.	tmpzr1t_l9r_go_relaxed.owl	uridine diphosphogalactose-glucose galactosyltransferase activity|UDPgalactose:D-glucose 4-beta-D-galactotransferase activity|UDPgalactose-glucose galactosyltransferase activity|UDP-galactose:D-glucose 4-beta-D-galactotransferase activity|UDP-galactose-glucose galactosyltransferase activity|lactose synthetase activity				MetaCyc:LACTOSE-SYNTHASE-RXN|EC:2.4.1.22|RHEA:12404|Reactome:R-HSA-5653878									molecular_function											owl:Class	
GO:0075258	biolink:NamedThing	negative regulation of teliospore formation	Any process that stops, prevents, or reduces the frequency, rate or extent of teliospore formation, which is the formation of a thick-walled resting or overwintering spore produced by the rust fungi (Uredinales) and smut fungi (Ustilaginales) in which karyogamy occurs.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1990209	biolink:NamedThing	negative regulation by symbiont of RNA levels in host	Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of the RNA levels in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl								ml	2013-10-09T18:09:33Z					biological_process											owl:Class	
GO:1900816	biolink:NamedThing	ochratoxin A metabolic process	The chemical reactions and pathways involving ochratoxin A.	tmpzr1t_l9r_go_relaxed.owl	Ochratoxin A metabolism							di	2012-06-04T10:13:02Z					biological_process											owl:Class	
GO:0072392	biolink:NamedThing	phenol catabolic process	The chemical reactions and pathways resulting in the breakdown of phenol, a compound that consists of a benzene ring with one attached hydroxyl group.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-12-06T04:08:44Z					biological_process											owl:Class	
GO:0102685	biolink:NamedThing	UDP-glucose:trans-zeatin 7-N-glucosyltransferase activity	Catalysis of the reaction: UDP-alpha-D-glucose + trans-zeatin <=> H+ + trans-zeatin-7-N-glucoside + UDP.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-4721									molecular_function											owl:Class	
GO:0052601	biolink:NamedThing	(S)-limonene 1,2-monooxygenase activity	Catalysis of the reaction: (4S)-limonene + NAD(P)H + H+ + O2 = NAD(P)+ + H2O + (4S)-limonene-1,2-epoxide.	tmpzr1t_l9r_go_relaxed.owl	(S)-limonene,NAD(P)H:oxygen oxidoreductase activity|(-)-limonene,NAD(P)H:oxygen oxidoreductase activity|(-)-limonene 1,2-monooxygenase activity				KEGG_REACTION:R09385|EC:1.14.13.107|MetaCyc:RXN-9409|KEGG_REACTION:R09389									molecular_function											owl:Class	
GO:0098963	biolink:NamedThing	dendritic transport of messenger ribonucleoprotein complex	The directed movement of a messenger ribonucleoprotein complex along microtubules in nerve cell dendrites.	tmpzr1t_l9r_go_relaxed.owl	dendritic transport of mRNA RNP complex													biological_process											owl:Class	
GO:0044225	biolink:NamedThing	apical pole of neuron	Portion of a neuron cell soma closest to the point where the apical dendrite emerges.	tmpzr1t_l9r_go_relaxed.owl					NIF_Subcellular:sao1186862860			jl	2009-11-13T03:49:14Z					cellular_component											owl:Class	
GO:0097749	biolink:NamedThing	membrane tubulation	A membrane organization process resulting in the formation of a tubular projection. This may face inwardly (as in tubular membrane invaginations) or outwardly (as in endosomal tubules).	tmpzr1t_l9r_go_relaxed.owl								pr	2016-12-21T12:32:24Z					biological_process											owl:Class	
GO:0033654	biolink:NamedThing	host cell chloroplast thylakoid membrane	Any sac-like membranous structures (cisternae) in a chloroplast found in host cells, combined into stacks (grana) and present singly in the stroma (stroma thylakoids or frets) as interconnections between grana. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0030046	biolink:NamedThing	parallel actin filament bundle assembly	Assembly of actin filament bundles in which the filaments are tightly packed (approximately 10-20 nm apart) and oriented with the same polarity.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0030772	biolink:NamedThing	tryptophan 2-C-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine(1+) + L-tryptophan = S-adenosyl-L-homocysteine + L-2-methyltryptophan + H(+).	tmpzr1t_l9r_go_relaxed.owl	tryptophan 2-methyltransferase activity|S-adenosylmethionine:tryptophan 2-methyltransferase activity|S-adenosyl-L-methionine:L-tryptophan 2-C-methyltransferase activity				EC:2.1.1.106|MetaCyc:TRYPTOPHAN-2-C-METHYLTRANSFERASE-RXN|RHEA:17321|KEGG_REACTION:R08547									molecular_function											owl:Class	
GO:0051540	biolink:NamedThing	metal cluster binding	Binding to a cluster of atoms including both metal ions and nonmetal atoms, usually sulfur and oxygen. Examples include iron-sulfur clusters and nickel-iron-sulfur clusters.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0090165	biolink:NamedThing	regulation of secretion by asymmetric Golgi ribbon formation	The asymmetric formation of a continuous ribbon of interconnected Golgi stacks of flat cisternae that modulates the controlled release of a substance from a polarized epithelial cell.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-12-08T09:05:16Z					biological_process											owl:Class	
GO:1905580	biolink:NamedThing	positive regulation of ERBB3 signaling pathway	Any process that activates or increases the frequency, rate or extent of ERBB3 signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	upregulation of ERBB3 signaling pathway|activation of ERBB3 signalling pathway|upregulation of HER3 signaling pathway|up regulation of HER3 signaling pathway|positive regulation of HER3 signaling pathway|up-regulation of receptor tyrosine-protein kinase erbB-3 signaling pathway|up regulation of ERBB3 signalling pathway|activation of HER3 signaling pathway|upregulation of ERBB3 signalling pathway|up-regulation of ERBB3 signaling pathway|up-regulation of ERBB3 signalling pathway|positive regulation of receptor tyrosine-protein kinase erbB-3 signaling pathway|up-regulation of HER3 signaling pathway|activation of ERBB3 signaling pathway|positive regulation of ERBB3 signalling pathway|activation of receptor tyrosine-protein kinase erbB-3 signaling pathway|up regulation of receptor tyrosine-protein kinase erbB-3 signaling pathway|upregulation of receptor tyrosine-protein kinase erbB-3 signaling pathway|up regulation of ERBB3 signaling pathway							als	2016-10-19T11:47:11Z					biological_process											owl:Class	
GO:0047514	biolink:NamedThing	1,3-beta-D-glucan phosphorylase activity	Catalysis of the reaction: [(1->3)-beta-D-glucosyl](n) + phosphate = [(1->3)-beta-D-glucosyl](n-1) + alpha-D-glucose 1-phosphate; substrates include laminarin.	tmpzr1t_l9r_go_relaxed.owl	1,3-beta-D-glucan:orthophosphate glucosyltransferase activity|laminarin phosphorylase activity|1,3-beta-D-glucan:phosphate alpha-D-glucosyltransferase activity|1,3-beta-glucan phosphorylase activity|laminarin phosphoryltransferase activity				MetaCyc:13-BETA-GLUCAN-PHOSPHORYLASE-RXN|EC:2.4.1.97									molecular_function											owl:Class	
GO:0009368	biolink:NamedThing	endopeptidase Clp complex	A protein complex comprised of members of the ClpX, ClpC, ClpD, ClpP or ClpR protein families. ClpPs are the proteolytic subunit of active complexes, and ClpA and ClpX form the regulatory subunits. Enzymatically active and inactive complexes can form.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:1990594	biolink:NamedThing	L-altrarate dehydratase activity	Catalysis of the reaction: L-altrarate = 5-dehydro-4-deoxy-D-glucarate + H(2)O.	tmpzr1t_l9r_go_relaxed.owl	L-talarate dehydratase activity				RHEA:44028			jl	2014-12-16T14:23:55Z					molecular_function											owl:Class	
GO:0000250	biolink:NamedThing	lanosterol synthase activity	Catalysis of the reaction: (S)-2,3-epoxysqualene = lanosterol. This is a cyclization reaction that forms the sterol nucleus.	tmpzr1t_l9r_go_relaxed.owl	2,3-oxidosqualene-lanosterol cyclase activity|lanosterol 2,3-oxidosqualene cyclase activity|2,3-epoxysqualene lanosterol cyclase activity|(S)-2,3-epoxysqualene mutase (cyclizing, lanosterol-forming)|oxidosqualene--lanosterol cyclase activity|2,3-epoxysqualene-lanosterol cyclase activity|2,3-oxidosqualene sterol cyclase activity|oxidosqualene:lanosterol cyclase activity|oxidosqualene-lanosterol cyclase activity|OSC|squalene epoxidase-cyclase activity|2,3-epoxysqualene--lanosterol cyclase activity|squalene 2,3-epoxide:lanosterol cyclase activity|squalene-2,3-oxide-lanosterol cyclase activity				KEGG_REACTION:R03199|MetaCyc:LANOSTEROL-SYNTHASE-RXN|RHEA:14621|EC:5.4.99.7|Reactome:R-HSA-191366									molecular_function											owl:Class	
GO:0035267	biolink:NamedThing	NuA4 histone acetyltransferase complex	A complex having histone acetylase activity on chromatin, as well as ATPase, DNA helicase and structural DNA binding activities. The complex is thought to be involved in double-strand DNA break repair. Subunits of the human complex include HTATIP/TIP60, TRRAP, RUVBL1, BUVBL2, beta-actin and BAF53/ACTL6A. In yeast, the complex has 13 subunits, including the catalytic subunit Esa1 (homologous to human Tip60).	tmpzr1t_l9r_go_relaxed.owl	TIP60 histone acetyltransferase complex|TIP60 histone acetylase complex													cellular_component											owl:Class	
GO:0043710	biolink:NamedThing	cell adhesion involved in multi-species biofilm formation	The attachment of a cell to a solid substrate, via cell adhesion molecules, contributing to the formation of a biofilm composed of microorganisms of different species.	tmpzr1t_l9r_go_relaxed.owl	cell adhesion during multi-species biofilm formation													biological_process											owl:Class	
GO:1902194	biolink:NamedThing	2-methylbut-2-enoyl-CoA(4-) biosynthetic process	The chemical reactions and pathways resulting in the formation of 2-methylbut-2-enoyl-CoA(4-).	tmpzr1t_l9r_go_relaxed.owl	2-methylbut-2-enoyl-CoA(4-) biosynthesis|2-methylbut-2-enoyl-CoA(4-) anabolism|2-methylbut-2-enoyl-CoA(4-) synthesis|2-methylbut-2-enoyl-CoA(4-) formation							ms	2013-06-06T09:40:46Z					biological_process											owl:Class	
GO:0009138	biolink:NamedThing	pyrimidine nucleoside diphosphate metabolic process	The chemical reactions and pathways involving pyrimidine nucleoside diphosphate, a compound consisting of a pyrimidine base linked to a ribose or deoxyribose sugar esterified with diphosphate on the sugar.	tmpzr1t_l9r_go_relaxed.owl	pyrimidine nucleoside diphosphate metabolism													biological_process											owl:Class	
GO:1990464	biolink:NamedThing	D-2-hydroxyacid dehydrogenase (quinone) activity	Catalysis of the reaction: (R)-2-hydroxyacid + a quinone = 2-oxoacid + a quinol.	tmpzr1t_l9r_go_relaxed.owl	(R)-2-hydroxyacid:quinone oxidoreductase activity|(R)-2-hydroxy acid dehydrogenase activity|D-lactate dehydrogenase activity|D-lactate:quinone oxidoreductase activity|(R)-2-hydroxy-acid:(acceptor) 2-oxidoreductase activity|D-lactate dehydrogenase (quinone) activity					(R)-lactate, (R)-malate and meso-tartrate are good substrates. Ubiquinone-1 and the dye 2,6-dichloroindophenol can act as acceptors; NAD+ and NADP+ are not acceptors.		pr	2014-08-22T10:13:42Z					molecular_function											owl:Class	
GO:0140367	biolink:NamedThing	antibacterial innate immune response	An defense response against a bacteria mediated through an innate immune response. An innate immune response is mediated by germline encoded components that directly recognize components of potential pathogens.	tmpzr1t_l9r_go_relaxed.owl								pg	2019-09-09T11:02:47Z					biological_process											owl:Class	
GO:1900523	biolink:NamedThing	positive regulation of response to amylopectin	Any process that activates or increases the frequency, rate or extent of response to amylopectin.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of response to amylopectin|upregulation of response to amylopectin|activation of response to amylopectin|up regulation of response to amylopectin							tt	2012-05-02T04:14:11Z					biological_process											owl:Class	
GO:0150166	biolink:NamedThing	regulation of histone H3-K4 acetylation	Any process that modulates the frequency, rate or extent of histone H3-K4 acetylation.	tmpzr1t_l9r_go_relaxed.owl								bc	2020-01-14T12:27:26Z					biological_process											owl:Class	
GO:1900383	biolink:NamedThing	regulation of synaptic plasticity by receptor localization to synapse	Any process that modulates synaptic plasticity, the ability of synapses to change as circumstances require, via receptor localization to the synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell. Processes may include receptor transport to, and/or maintenance at, the synapse.	tmpzr1t_l9r_go_relaxed.owl	regulation of synaptic plasticity by receptor localisation to synapse							kmv	2012-04-17T04:44:37Z					biological_process											owl:Class	
GO:0001001	biolink:NamedThing	mitochondrial single-subunit type RNA polymerase binding	Binding to a single subunit mitochondrial RNA polymerase enzyme, which is composed of a single catalytic subunit similar to the RNA polymerase enzymes from phages T3, T7, and SP6.	tmpzr1t_l9r_go_relaxed.owl								krc	2010-08-17T05:01:28Z					molecular_function											owl:Class	
GO:0034070	biolink:NamedThing	aminoglycoside 1-N-acetyltransferase activity	Catalysis of the reaction: acetyl-CoA + aminoglycoside = CoA + 1-N-acetylaminoglycoside. This is acetylation of the 1-amino group of the central deoxystreptamine ring.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0034069	biolink:NamedThing	aminoglycoside N-acetyltransferase activity	Catalysis of the reaction: acetyl-CoA + aminoglycoside = CoA + N-acetylaminoglycoside.	tmpzr1t_l9r_go_relaxed.owl	kanamycin acetyltransferase activity													molecular_function											owl:Class	
GO:0031764	biolink:NamedThing	type 1 galanin receptor binding	Binding to a type 1 galanin receptor.	tmpzr1t_l9r_go_relaxed.owl	type 1 galanin receptor ligand													molecular_function											owl:Class	
GO:1903709	biolink:NamedThing	uterine gland development	The process whose specific outcome is the progression of an uterine gland over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl	uterine glands set development|glandulae uterinae development|uterine glands development|set of uterine glands development|endometrium gland development|endometrial gland development|glandular part of endometrium development							cls	2014-12-04T18:57:21Z					biological_process											owl:Class	
GO:0016229	biolink:NamedThing	steroid dehydrogenase activity	Catalysis of an oxidation-reduction (redox) reaction in which one substrate is a sterol derivative.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0051585	biolink:NamedThing	negative regulation of dopamine uptake involved in synaptic transmission	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of dopamine into a presynaptic neuron or glial cell.	tmpzr1t_l9r_go_relaxed.owl	down regulation of dopamine uptake involved in synaptic transmission|down-regulation of dopamine uptake involved in synaptic transmission|downregulation of dopamine uptake involved in synaptic transmission|negative regulation of dopamine import involved in synaptic transmission													biological_process											owl:Class	
GO:0005385	biolink:NamedThing	zinc ion transmembrane transporter activity	Enables the transfer of zinc (Zn) ions from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	cobalt, zinc uptake permease activity|zinc, iron permease activity|zinc, cadmium uptake permease activity|zinc, cadmium, cobalt, nickel, lead-efflux ATPase activity				RHEA:29351|Reactome:R-HSA-442393|Reactome:R-HSA-435375|Reactome:R-HSA-437084|Reactome:R-HSA-442422|Reactome:R-HSA-442405|Reactome:R-HSA-437136|Reactome:R-HSA-435366|Reactome:R-HSA-5654125|Reactome:R-HSA-442345|Reactome:R-HSA-442317|Reactome:R-HSA-442387|Reactome:R-HSA-437085|Reactome:R-HSA-437129|Reactome:R-HSA-437139									molecular_function											owl:Class	
GO:0039644	biolink:NamedThing	suppression by virus of host NF-kappaB cascade	Any process in which a virus stops, prevents, or reduces a host NF-kappaB cascade.	tmpzr1t_l9r_go_relaxed.owl	inhibition of host NF-kappa-B by virus|suppression by virus of host NF-kappaB transcription factor activity							bf	2012-10-09T15:04:27Z					biological_process											owl:Class	
GO:0002055	biolink:NamedThing	adenine binding	Binding to adenine, a purine base.	tmpzr1t_l9r_go_relaxed.owl	6-aminopurine binding													molecular_function											owl:Class	
GO:0009444	biolink:NamedThing	pyruvate oxidation	The chemical reactions and pathways resulting in the conversion of pyruvate to acetylphosphate.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:PYRUVOX-PWY|Wikipedia:Pyruvate_decarboxylation									biological_process											owl:Class	
GO:0031839	biolink:NamedThing	type 1 neuromedin U receptor binding	Binding to a type 1 neuromedin U receptor.	tmpzr1t_l9r_go_relaxed.owl	type 1 neuromedin U receptor ligand													molecular_function											owl:Class	
GO:0042922	biolink:NamedThing	neuromedin U receptor binding	Binding to one or more specific sites on a neuromedin U receptor.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0047055	biolink:NamedThing	salutaridine synthase activity	Catalysis of the reaction: (R)-reticuline + [reduced NADPH--hemoprotein reductase] + O2 -> salutaridine + [oxidized NADPH--hemoprotein reductase] + 2 H2O.	tmpzr1t_l9r_go_relaxed.owl	(R)-reticuline oxidase (C-C phenol-coupling) activity	https://github.com/geneontology/go-ontology/issues/21133			MetaCyc:1.1.3.35-RXN|EC:1.14.19.67|KEGG_REACTION:R04696|RHEA:17713									molecular_function											owl:Class	
GO:0019503	biolink:NamedThing	stachydrine biosynthetic process	The chemical reactions and pathways resulting in the formation of stachydrine, N-methylproline methylbetaine, the betaine derivative of L-proline.	tmpzr1t_l9r_go_relaxed.owl	stachydrine formation|stachydrine synthesis|stachydrine anabolism|stachydrine biosynthesis													biological_process											owl:Class	
GO:0102917	biolink:NamedThing	(S)-reticuline 7-O-methyltransferase activity	Catalysis of the reaction: (S)-reticulinium(1+) + S-adenosyl-L-methionine  <=> H+ + laudanine(1+) + S-adenosyl-L-homocysteine.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-8700|EC:2.1.1.291|RHEA:10444									molecular_function											owl:Class	
GO:0070086	biolink:NamedThing	ubiquitin-dependent endocytosis	Endocytosis of a protein that requires the substrate to be modified by ubiquitination. Several plasma membrane proteins, including cell surface permeases and some receptors, are targeted for internalization by endocytosis, and are thereafter delivered to the vacuole or lysosome, where they are degraded.	tmpzr1t_l9r_go_relaxed.owl	ubiquitin-mediated endocytosis													biological_process											owl:Class	
GO:0043831	biolink:NamedThing	thiosulfate dehydrogenase (quinone) activity	Catalysis of the reaction: 6-decylubiquinone + 2 thiosulfate = 6-decylubiquinol + tetrathionate.	tmpzr1t_l9r_go_relaxed.owl	DoxD|thiosulphate:quinone oxidoreductase activity|thiosulfate:quinone oxidoreductase activity|DoxA|thiosulphate dehydrogenase (quinone) activity|TQO|thiosulfate:6-decylubiquinone oxidoreductase activity|thiosulfate oxidoreductase, tetrathionate-forming activity				KEGG_REACTION:R07177|MetaCyc:1.8.5.2-RXN|RHEA:10936|EC:1.8.5.2									molecular_function											owl:Class	
GO:0016672	biolink:NamedThing	oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which a sulfur-containing group acts as a hydrogen or electron donor and reduces quinone or a related compound.	tmpzr1t_l9r_go_relaxed.owl	oxidoreductase activity, acting on sulphur group of donors, quinone or similar compound as acceptor				EC:1.8.5.-									molecular_function											owl:Class	
GO:0061750	biolink:NamedThing	acid sphingomyelin phosphodiesterase activity	Catalysis of the reaction: H(2)O + sphingomyelin = ceramide + choline phosphate + H(+) in an acidic environment.	tmpzr1t_l9r_go_relaxed.owl	acid SMase|acid sphingomyelinase							dph	2015-11-11T14:47:45Z					molecular_function											owl:Class	
GO:0047966	biolink:NamedThing	glycosulfatase activity	Catalysis of the reaction: D-glucose 6-sulfate + H(2)O = D-glucose + H(+) + sulfate.	tmpzr1t_l9r_go_relaxed.owl	glucosulfatase activity|glycosulphatase activity|sugar-sulfate sulfohydrolase activity				RHEA:19145|MetaCyc:GLYCOSULFATASE-RXN|EC:3.1.6.3|KEGG_REACTION:R00534									molecular_function											owl:Class	
GO:0039687	biolink:NamedThing	viral DNA strand displacement replication	A viral DNA replication process where only one strand is replicated at once, and which releases a single stranded DNA (ssDNA).	tmpzr1t_l9r_go_relaxed.owl					VZ:1940			bf	2013-10-17T14:48:40Z					biological_process											owl:Class	
GO:0045170	biolink:NamedThing	spectrosome	A germline specific spherical organelle, rich in membrane skeletal proteins. Precursor to the fusome.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0102505	biolink:NamedThing	apigeninidin 5-O-glucosyltransferase activity	Catalysis of the reaction: apigeninidin + UDP-alpha-D-glucose <=> apigeninidin 5-O-glucoside + UDP + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-14427									molecular_function											owl:Class	
GO:0071278	biolink:NamedThing	cellular response to cesium ion	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cesium stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to cesium							mah	2009-12-10T03:55:44Z					biological_process											owl:Class	
GO:0099613	biolink:NamedThing	protein localization to cell wall	The process of directing proteins towards the cell-wall.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0052381	biolink:NamedThing	tRNA dimethylallyltransferase activity	Catalysis of the reaction: dimethylallyl diphosphate + tRNA = diphosphate + tRNA containing 6-dimethylallyladenosine.	tmpzr1t_l9r_go_relaxed.owl	tRNA prenyltransferase activity|tRNA isopentenyltransferase activity|dimethylallyl-diphosphate:tRNA dimethylallyltransferase activity				Reactome:R-HSA-6784462|Reactome:R-HSA-6787567|EC:2.5.1.75|MetaCyc:RXN0-6274|RHEA:26482	Note that this activity was formerly know in GO and EC as 'tRNA isopentenyltransferase' (EC:2.5.1.8, GO:0004811), but it is now known that dimethylallyl diphosphate, rather than isopentenyl diphosphate, is the substrate.			2010-07-23T03:07:33Z			GO:0004811		molecular_function											owl:Class	
GO:1902515	biolink:NamedThing	thioredoxin-disulfide reductase complex	A protein complex which is capable of thioredoxin-disulfide reductase activity.	tmpzr1t_l9r_go_relaxed.owl						An example of this is thioredoxin reductase (TrxB) in E. coli [P0A9P4] in PMID:10947986.		bhm	2013-11-26T11:43:38Z					cellular_component											owl:Class	
GO:0102459	biolink:NamedThing	8-oxo-deoxyadenine diphosphate phosphatase activity	Catalysis of the reaction: 8-oxo-dADP + H2O = 8-oxo-dAMP + hydrogenphosphate + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-14005									molecular_function											owl:Class	
GO:0008728	biolink:NamedThing	GTP diphosphokinase activity	Catalysis of the reaction: ATP + GTP = AMP + guanosine 3'-diphosphate 5'-triphosphate.	tmpzr1t_l9r_go_relaxed.owl	ppGpp synthetase I activity|(p)ppGpp synthetase I|ATP-GTP 3'-diphosphotransferase activity|guanosine 3',5'-polyphosphate synthase activity|GPSII|stringent factor activity|guanosine 5',3'-polyphosphate synthetase activity|GTP pyrophosphokinase activity|ATP:GTP 3'-diphosphotransferase activity|(p)ppGpp synthetase II|GPSI|guanosine pentaphosphate synthetase activity				MetaCyc:GTPPYPHOSKIN-RXN|EC:2.7.6.5|RHEA:22088									molecular_function											owl:Class	
GO:0097419	biolink:NamedThing	Pick body	Cellular inclusion composed of numerous tau fibrils arranged in a disorderly array. Tau protein is a major component, though Pick bodies also contain ubiquitin, alpha-synuclein, and apolipoprotein E.	tmpzr1t_l9r_go_relaxed.owl					NIF_Subcellular:nlx_subcell_20090102			pr	2012-11-06T20:57:02Z					cellular_component											owl:Class	
GO:0019367	biolink:NamedThing	fatty acid elongation, saturated fatty acid	Elongation of a saturated fatty acid chain.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:FASYN-ELONG-PWY									biological_process											owl:Class	
GO:0051519	biolink:NamedThing	activation of bipolar cell growth	Any process that initiates the inactive process of bipolar cell growth, polarized growth from both ends of a cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0015520	biolink:NamedThing	tetracycline:proton antiporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + tetracycline(in) = H+(in) + tetracycline(out).	tmpzr1t_l9r_go_relaxed.owl	tetracycline:hydrogen antiporter activity|tetracyclin:hydrogen antiporter activity|tetracyclin:proton antiporter activity													molecular_function											owl:Class	
GO:0017099	biolink:NamedThing	very-long-chain-acyl-CoA dehydrogenase activity	Catalysis of the reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor, where the acyl group is a very long chain fatty acid residue. A very long-chain fatty acid is a fatty acid which has a chain length greater than C22.	tmpzr1t_l9r_go_relaxed.owl	very long-chain-acyl-CoA dehydrogenase activity				Reactome:R-HSA-548831									molecular_function											owl:Class	
GO:0004466	biolink:NamedThing	long-chain-acyl-CoA dehydrogenase activity	Catalysis of the reaction: acyl-CoA + ETF = 2,3-dehydroacyl-CoA + reduced ETF.	tmpzr1t_l9r_go_relaxed.owl	palmitoyl-coenzyme A dehydrogenase activity|palmitoyl-CoA dehydrogenase activity|long-chain-acyl-CoA:acceptor 2,3-oxidoreductase activity|long-chain-acyl-CoA:(acceptor) 2,3-oxidoreductase activity|long-chain acyl-coenzyme A dehydrogenase activity				EC:1.3.8.8|MetaCyc:LONG-CHAIN-ACYL-COA-DEHYDROGENASE-RXN|RHEA:17721									molecular_function											owl:Class	
GO:0042951	biolink:NamedThing	arbutin transmembrane transporter activity	Enables the transfer of arbutin, a glycoside found in the bearberry and related plants which has been used to treat urinary-tract diseases, from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0015573	biolink:NamedThing	beta-glucoside transmembrane transporter activity	Enables the transfer of beta-glucosides from one side of a membrane to the other. Beta-glucosides are glycosides in which the sugar group is a glucose residue, and the anomeric carbon of the bond is in a beta configuration.	tmpzr1t_l9r_go_relaxed.owl	beta-glucoside permease activity											GO:0015582		molecular_function											owl:Class	
GO:0032491	biolink:NamedThing	detection of molecule of fungal origin	The series of events in which a stimulus from a molecule of fungal origin is received and converted into a molecular signal.	tmpzr1t_l9r_go_relaxed.owl	detection of fungus associated molecule|detection of fungal associated molecule													biological_process											owl:Class	
GO:0001855	biolink:NamedThing	complement component C4b binding	Binding to a C4b product of the classical complement cascade.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0031715	biolink:NamedThing	C5L2 anaphylatoxin chemotactic receptor binding	Binding to a C5L2 anaphylatoxin chemotactic receptor.	tmpzr1t_l9r_go_relaxed.owl	C5L2 anaphylatoxin chemotactic receptor ligand													molecular_function											owl:Class	
GO:0031714	biolink:NamedThing	C5a anaphylatoxin chemotactic receptor binding	Binding to a C5a anaphylatoxin chemotactic receptor.	tmpzr1t_l9r_go_relaxed.owl	C5a anaphylatoxin chemotactic receptor ligand													molecular_function											owl:Class	
GO:0046825	biolink:NamedThing	regulation of protein export from nucleus	Any process that modulates the frequency, rate or extent of the directed movement of proteins from the nucleus to the cytoplasm.	tmpzr1t_l9r_go_relaxed.owl	regulation of protein transport from nucleus to cytoplasm|regulation of protein export from cell nucleus|regulation of protein-nucleus export|regulation of protein export out of nucleus													biological_process											owl:Class	
GO:0046897	biolink:NamedThing	N-terminal peptidyl-tyrosine methylation	The methylation of the N-terminal tyrosine of proteins to form the derivative N-methyl-L-tyrosine.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0338									biological_process											owl:Class	
GO:0007594	biolink:NamedThing	puparial adhesion	The adhesion of the puparia of Diptera to their substrate; normally effected by a 'glue' secreted by the larval salivary gland and expectorated at the time of pupariation.	tmpzr1t_l9r_go_relaxed.owl	puparial glue													biological_process											owl:Class	
GO:0008955	biolink:NamedThing	peptidoglycan glycosyltransferase activity	Catalysis of the reaction: [GlcNAc-(1,4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n)-diphosphoundecaprenol + GlcNAc-(1,4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol = [GlcNAc-(1,4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n+1)-diphosphoundecaprenol + undecaprenyl diphosphate.	tmpzr1t_l9r_go_relaxed.owl	penicillin binding protein (3 or 1B) activity|peptidoglycan transglycosylase activity|PG-II activity|undecaprenyldiphospho-N-acetyl-D-glucosaminyl-(1->4)-(N-acetyl-D-muramoylpentapeptide):undecaprenyldiphospho-(N-acetyl-D-glucosaminyl-(1->4)-N-acetyl-D-muramoylpentapeptide) disaccharidetransferase activity|bactoprenyldiphospho-N-acetylmuramoyl-(N-acetyl-D-glucosaminyl)-pentapeptide:peptidoglycan N-acetylmuramoyl-N-acetyl-D-glucosaminyltransferase activity|peptidoglycan TGase activity				EC:2.4.1.129|MetaCyc:RXN0-5405|RHEA:23708									molecular_function											owl:Class	
GO:0043183	biolink:NamedThing	vascular endothelial growth factor receptor 1 binding	Binding to a vascular endothelial growth factor receptor 1.	tmpzr1t_l9r_go_relaxed.owl	VEGFR 1 binding|Flt-1 binding|VEGF receptor 1 binding													molecular_function											owl:Class	
GO:1903617	biolink:NamedThing	positive regulation of mitotic cytokinesis, site selection	Any process that activates or increases the frequency, rate or extent of mitotic cytokinesis, site selection.	tmpzr1t_l9r_go_relaxed.owl								vw	2014-11-19T10:52:25Z					biological_process											owl:Class	
GO:0106230	biolink:NamedThing	protein depropionylation	The removal of a propionyl group from a residue in a peptide or protein.	tmpzr1t_l9r_go_relaxed.owl								hjd	2019-10-17T19:10:50Z					biological_process											owl:Class	
GO:0002359	biolink:NamedThing	B-1 B cell proliferation	The expansion of a B-1 B cell by cell division. Follows B cell activation.	tmpzr1t_l9r_go_relaxed.owl	B-1 B-cell proliferation|B-1 B-lymphocyte proliferation|B-1 B lymphocyte proliferation													biological_process											owl:Class	
GO:0032884	biolink:NamedThing	regulation of cell wall chitin biosynthetic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cell wall chitin.	tmpzr1t_l9r_go_relaxed.owl	regulation of cell wall chitin synthesis|regulation of cell wall chitin anabolism|regulation of cell wall chitin biosynthesis|regulation of cell wall chitin formation													biological_process											owl:Class	
GO:0098991	biolink:NamedThing	kainate selective glutamate receptor signaling pathway	A series of molecular signals initiated by glutamate binding to an kainate-selective glutamate receptor on the surface of the target cell, followed by the movement of ions through a channel in the receptor complex. Ends with regulation of a downstream cellular process, e.g. transcription.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0035037	biolink:NamedThing	sperm entry	An endocytosis process that results in penetration of the egg shell through the micropyle (a specialized anterior opening in the vitelline envelope) and entry of the entire sperm, including the surrounding plasma membrane and the sperm tail, into the egg cytoplasm. This step in fertilization is seen in Drosophila, where a plasma membrane fusion event between the sperm and the egg does not occur.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0061085	biolink:NamedThing	regulation of histone H3-K27 methylation	Any process that modulates the rate, frequency, or extent of histone H3-K27 methylation. Histone H3-K27 methylation is the modification of histone H3 by addition of a methyl group to lysine at position 27 of the histone.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-04-26T01:23:52Z					biological_process											owl:Class	
GO:0016166	biolink:NamedThing	phytoene dehydrogenase activity	Catalysis of the dehydrogenation of phytoene to produce a carotenoid intermediate such as phytofluene.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0052075	biolink:NamedThing	positive regulation by symbiont of host jasmonic acid-mediated defense response	Any process in which a symbiont activates, maintains or increases the frequency, rate or extent of the jasmonic acid-mediated defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	induction by organism of host jasmonic acid-mediated defense response|induction by organism of host JA-mediated defense response|activation by symbiont of host jasmonic acid-mediated defense response|up-regulation by symbiont of host jasmonic acid-mediated defense response|stimulation by symbiont of host jasmonic acid-mediated defense response|positive regulation by organism of host JA-mediated defense response|upregulation by symbiont of host jasmonic acid-mediated defense response|positive regulation by organism of jasmonic acid-mediated defense response of other organism involved in symbiotic interaction|up regulation by symbiont of host jasmonic acid-mediated defense response											GO:0052273		biological_process											owl:Class	
GO:0042968	biolink:NamedThing	homoserine transport	The directed movement of homoserine, alpha-amino-gamma-hydroxybutyric acid, an intermediate in the biosynthesis of cystathionine, threonine and methionine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1903460	biolink:NamedThing	mitotic DNA replication leading strand elongation	Any leading strand elongation that is involved in mitotic cell cycle DNA replication.	tmpzr1t_l9r_go_relaxed.owl	leading strand elongation involved in DNA replication during S phase involved in mitotic cell cycle|leading strand elongation involved in DNA replication involved in S-phase involved in mitotic cell cycle|leading strand elongation involved in mitotic nuclear cell cycle DNA replication|leading strand elongation involved in DNA replication involved in S phase involved in mitotic cell cycle|leading strand elongation involved in nuclear cell cycle DNA replication involved in mitotic cell cycle|leading strand elongation involved in mitotic DNA replication							vw	2014-09-23T13:33:03Z					biological_process											owl:Class	
GO:0033056	biolink:NamedThing	D-ornithine metabolic process	The chemical reactions and pathways involving D-ornithine, the D-enantiomer of the amino acid ornithine, i.e. (2R)-2,5-diaminopentanoic acid.	tmpzr1t_l9r_go_relaxed.owl	D-ornithine metabolism													biological_process											owl:Class	
GO:0102830	biolink:NamedThing	verbascose synthase activity	Catalysis of the reaction: 2 stachyose <=> verbascose + raffinose.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-8286									molecular_function											owl:Class	
GO:0001653	biolink:NamedThing	peptide receptor activity	Combining with an extracellular or intracellular peptide to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	exogenous peptide receptor activity|endogenous peptide receptor activity													molecular_function											owl:Class	
GO:0099127	biolink:NamedThing	envenomation resulting in positive regulation of argininosuccinate synthase activity in other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the activation of the cytosolic argininosuccinate synthase in the bitten organism.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1904070	biolink:NamedThing	ascaroside biosynthetic process	The chemical reactions and pathways resulting in the formation of ascaroside.	tmpzr1t_l9r_go_relaxed.owl	ascaroside formation|ascaroside synthesis|ascaroside biosynthesis|ascaroside anabolism							kmv	2015-03-20T02:40:20Z					biological_process											owl:Class	
GO:1904069	biolink:NamedThing	ascaroside metabolic process	The chemical reactions and pathways involving ascaroside.	tmpzr1t_l9r_go_relaxed.owl	ascaroside metabolism							kmv	2015-03-20T02:40:14Z					biological_process											owl:Class	
GO:0047464	biolink:NamedThing	heparosan-N-sulfate-glucuronate 5-epimerase activity	Catalysis of the reaction: heparosan-N-sulfate D-glucuronate = heparosan-N-sulfate L-iduronate.	tmpzr1t_l9r_go_relaxed.owl	polyglucuronate epimerase activity|heparosan-N-sulfate-D-glucuronosyl 5-epimerase activity|poly[(1,4)-beta-D-glucuronosyl-(1,4)-N-sulfo-alpha-D-glucosaminyl] glucurono-5-epimerase activity|heparosan-N-sulphate-glucuronate 5-epimerase activity|D-glucuronyl C-5 epimerase activity|heparosan epimerase activity|C-5 uronosyl epimerase activity				MetaCyc:5.1.3.17-RXN|EC:5.1.3.17|RHEA:20197									molecular_function											owl:Class	
GO:0009990	biolink:NamedThing	contact guidance	Cell recognition involving the deposition of specific pathways in the extracellular matrix that guide migrating cells.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0009989	biolink:NamedThing	cell-matrix recognition	Cell recognition that involves the interaction of the cell with the extracellular matrix.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0102115	biolink:NamedThing	peptidoglycan asparagine synthase activity	Catalysis of the reaction: ditrans,octacis-undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-gamma-D-isoglutaminyl-N-(beta-D-asparatyl)-L-lysyl-D-alanyl-D-alanine + ammonium + ATP = H+ + ditrans,octacis-undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-gamma-D-isoglutaminyl-N-(beta-D-asparaginyl)-L-lysyl-D-alanyl-D-alanine + AMP + diphosphoric acid.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-11338									molecular_function											owl:Class	
GO:0032164	biolink:NamedThing	hyphal septin cap	A faint structure formed of septins found at the leading edge of growth in hyphae of fungal cells growing filamentously. This cap of septins colocalizes with a region of the plasma membrane that is rich in ergosterol.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0090491	biolink:NamedThing	N-hydroxy-L-tryptophan,NADPH:oxygen oxidoreductase (N-hydroxylating)	Catalyzes the reaction: N-Hydroxy-L-tryptophan + Oxygen + NADPH + H+ = N,N-Dihydroxy-L-tryptophan + NADP+ + H2O.	tmpzr1t_l9r_go_relaxed.owl								tb	2012-10-16T16:27:19Z					molecular_function											owl:Class	
GO:2000381	biolink:NamedThing	negative regulation of mesoderm development	Any process that stops, prevents or reduces the frequency, rate or extent of mesoderm development.	tmpzr1t_l9r_go_relaxed.owl								vk	2011-02-15T03:10:02Z					biological_process											owl:Class	
GO:2000380	biolink:NamedThing	regulation of mesoderm development	Any process that modulates the frequency, rate or extent of mesoderm development.	tmpzr1t_l9r_go_relaxed.owl								vk	2011-02-15T03:09:46Z					biological_process											owl:Class	
GO:0033364	biolink:NamedThing	mast cell secretory granule organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a secretory granule in a mast cell. A secretory granule is a small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion.	tmpzr1t_l9r_go_relaxed.owl	mast cell secretory granule maturation|mast cell secretory granule organization and biogenesis|mast cell secretory granule organisation													biological_process											owl:Class	
GO:0070835	biolink:NamedThing	chromium ion transmembrane transporter activity	Enables the transfer of chromium (Cr) ions from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-07-30T03:04:09Z					molecular_function											owl:Class	
GO:0031733	biolink:NamedThing	CCR8 chemokine receptor binding	Binding to a CCR8 chemokine receptor.	tmpzr1t_l9r_go_relaxed.owl	CCR8 chemokine receptor ligand													molecular_function											owl:Class	
GO:0031142	biolink:NamedThing	induction of conjugation upon nitrogen starvation	The process in which a cell initiates conjugation with cellular fusion upon nitrogen starvation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0000452	biolink:NamedThing	snoRNA guided rRNA 2'-O-methylation	The posttranscriptional addition of methyl groups to the 2'-oxygen atom of nucleotide residues in an rRNA molecule during ribosome biogenesis using a snoRNA guide that targets the position of methylation.	tmpzr1t_l9r_go_relaxed.owl	snoRNA guided rRNA 2'-O-ribose methylation													biological_process											owl:Class	
GO:0033512	biolink:NamedThing	L-lysine catabolic process to acetyl-CoA via saccharopine	The chemical reactions and pathways resulting in the breakdown of L-lysine into other compounds, including acetyl-CoA, via the intermediate saccharopine.	tmpzr1t_l9r_go_relaxed.owl	L-lysine degradation to acetyl-CoA via saccharopine|L-lysine breakdown to acetyl-CoA via saccharopine				MetaCyc:LYSINE-DEG1-PWY									biological_process											owl:Class	
GO:0035946	biolink:NamedThing	mitochondrial mRNA surveillance	The set of processes involved in identifying and degrading messenger RNA (mRNA) within the mitochondrion.	tmpzr1t_l9r_go_relaxed.owl	mitochondrial aberrant RNA catabolic process|mitochondrial mRNA quality control|mitochondrial messenger RNA surveillance							bf	2011-07-28T10:37:07Z					biological_process											owl:Class	
GO:0052831	biolink:NamedThing	inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity	Catalysis of the reaction: inositol-1,3,4,6-tetrakisphosphate + H2O = inositol-3,4,6-trisphosphate + phosphate.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-1855159			ai	2011-11-29T10:58:27Z					molecular_function											owl:Class	
GO:0031852	biolink:NamedThing	mu-type opioid receptor binding	Binding to a mu-type opioid receptor.	tmpzr1t_l9r_go_relaxed.owl	mu-type opioid receptor ligand|morphine receptor binding													molecular_function											owl:Class	
GO:0018061	biolink:NamedThing	peptidyl-L-3-phenyllactic acid biosynthetic process from peptidyl-phenylalanine	The modification of a N-terminal peptidyl-phenylalanine residue by either oxidative deamination or by transamination and subsequent reduction to form peptidyl-L-3-phenyllactic acid.	tmpzr1t_l9r_go_relaxed.owl	peptidyl-L-3-phenyllactic acid anabolism from peptidyl-phenylalanine|peptidyl-L-3-phenyllactic acid formation from peptidyl-phenylalanine|peptidyl-L-3-phenyllactic acid synthesis from peptidyl-phenylalanine				RESID:AA0128									biological_process											owl:Class	
GO:0007111	biolink:NamedThing	meiosis II cytokinesis	A cell cycle process that results in the division of the cytoplasm of a cell after meiosis II, resulting in the separation of the original cell into two daughter cells.	tmpzr1t_l9r_go_relaxed.owl	cytokinesis after meiosis II													biological_process											owl:Class	
GO:0080124	biolink:NamedThing	pheophytinase activity	Catalysis of the reaction: pheophytin + H2O = phytol + pheophorbide.	tmpzr1t_l9r_go_relaxed.owl	pheophytin pheophorbide hydrolase activity							dhl	2009-04-28T04:16:11Z					molecular_function											owl:Class	
GO:0010122	biolink:NamedThing	arginine catabolic process to alanine via ornithine	The chemical reactions and pathways resulting in the breakdown of arginine into other compounds, including alanine, via ornithine.	tmpzr1t_l9r_go_relaxed.owl	arginine breakdown to alanine via ornithine|arginine degradation to alanine via ornithine				MetaCyc:ARGORNPROST-PWY									biological_process											owl:Class	
GO:1904094	biolink:NamedThing	positive regulation of autophagic cell death	Any process that activates or increases the frequency, rate or extent of autophagic cell death.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of programmed cell death by macroautophagy|positive regulation of type II programmed cell death|activation of autophagic cell death|upregulation of type II programmed cell death|up-regulation of type II programmed cell death|activation of programmed cell death by macroautophagy|up-regulation of autophagic cell death|up regulation of type II programmed cell death|up-regulation of programmed cell death by macroautophagy|upregulation of programmed cell death by macroautophagy|up regulation of autophagic cell death|up regulation of programmed cell death by macroautophagy|activation of type II programmed cell death|upregulation of autophagic cell death							bhm	2015-03-26T16:41:45Z					biological_process											owl:Class	
GO:1904096	biolink:NamedThing	protein tyrosine phosphatase complex	A protein complex which is capable of protein tyrosine phosphatase activity.	tmpzr1t_l9r_go_relaxed.owl						An example of this is ACPP in human (UniProt symbol P15309) in PMID:22389722 (inferred from physical interaction).		bhm	2015-03-27T14:34:59Z					cellular_component											owl:Class	
GO:0052076	biolink:NamedThing	induction by symbiont of host ethylene-mediated defense response	Any process in which an organism activates, maintains or increases the frequency, rate or extent of the ethylene-mediated defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	positive regulation by organism of ethylene-mediated defense response of other organism involved in symbiotic interaction|positive regulation by organism of defense-related ethylene-mediated signal transduction pathway in other organism involved in symbiotic interaction|upregulation by symbiont of host ethylene-mediated defense response|up regulation by symbiont of host ethylene-mediated defense response|up-regulation by symbiont of host ethylene-mediated defense response|positive regulation by symbiont of host ethylene-mediated defense response|positive regulation by symbiont of defense-related host ethylene-mediated signal transduction pathway|activation by symbiont of host ethylene-mediated defense response|stimulation by symbiont of host ethylene-mediated defense response											GO:0052269|GO:0052071|GO:0052274		biological_process											owl:Class	
GO:0044164	biolink:NamedThing	host cell cytosol	The part of the host cell cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.	tmpzr1t_l9r_go_relaxed.owl	host cytosol							jl	2009-09-04T11:03:27Z					cellular_component											owl:Class	
GO:0031797	biolink:NamedThing	type 2 metabotropic GABA receptor binding	Binding to a type 2 metabotropic GABA receptor.	tmpzr1t_l9r_go_relaxed.owl	type 2 metabotropic GABA receptor ligand													molecular_function											owl:Class	
GO:0001975	biolink:NamedThing	response to amphetamine	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amphetamine stimulus. Amphetamines consist of a group of compounds related to alpha-methylphenethylamine.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0044064	biolink:NamedThing	modulation by symbiont of host respiratory system process	The alteration by a symbiont organism of the functioning of a respiratory system process, an organ system process carried out by any of the organs or tissues of the respiratory system.	tmpzr1t_l9r_go_relaxed.owl	regulation by symbiont of host respiratory system process													biological_process											owl:Class	
GO:0047813	biolink:NamedThing	D-arabinitol 4-dehydrogenase activity	Catalysis of the reaction: D-arabinitol + NAD+ = D-xylulose + NADH.	tmpzr1t_l9r_go_relaxed.owl					EC:1.1.1.11|RHEA:17921|MetaCyc:D-ARABINITOL-4-DEHYDROGENASE-RXN									molecular_function											owl:Class	
GO:0033447	biolink:NamedThing	AGA codon-amino acid adaptor activity	A triplet codon-amino acid adaptor activity that recognizes an AGA codon.	tmpzr1t_l9r_go_relaxed.owl	arginine tRNA					Note that in the standard genetic code, AGA codes for arginine.								molecular_function											owl:Class	
GO:2000873	biolink:NamedThing	regulation of histone H4 acetylation involved in response to DNA damage stimulus	Any process that modulates the frequency, rate or extent of histone H4 acetylation involved in response to DNA damage stimulus.	tmpzr1t_l9r_go_relaxed.owl	regulation of histone H4 acetylation involved in DNA damage response|regulation of histone H4 acetylation involved in cellular response to DNA damage stimulus|regulation of histone H4 acetylation involved in cellular DNA damage response|regulation of histone H4 acetylation involved in response to DNA damage|regulation of histone H4 acetylation involved in response to genotoxic stress							mah	2011-07-26T10:05:23Z					biological_process											owl:Class	
GO:0102814	biolink:NamedThing	caffeoyl-CoA:delphinidin-3,5,3'-triglucoside 5-O-glucoside-6-O-hydroxycinnamoyltransferase activity	Catalysis of the reaction: delphinidin 3,3',5-tri-O-beta-D-glucoside betaine + caffeoyl-CoA <=> delphinidin 3-O-glucosyl-5-O-(caffeoylglucoside-3'-O-glucoside) + coenzyme A.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-8232									molecular_function											owl:Class	
GO:0102897	biolink:NamedThing	abietadienal hydroxylase activity	Catalysis of the reaction: abietal + NADPH + O2 <=> abietate + NADP + H2O.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-8510|RHEA:56928									molecular_function											owl:Class	
GO:1901143	biolink:NamedThing	insulin catabolic process	The chemical reactions and pathways resulting in the breakdown of insulin.	tmpzr1t_l9r_go_relaxed.owl	insulin breakdown|insulin catabolism|insulin degradation							pm	2012-07-13T12:33:03Z					biological_process											owl:Class	
GO:0060683	biolink:NamedThing	regulation of branching involved in salivary gland morphogenesis by epithelial-mesenchymal signaling	Any process that modulates the rate, frequency, or extent of salivary gland branching as a result of the transfer of information from the epithelial cells to the mesenchymal cells of the salivary gland.	tmpzr1t_l9r_go_relaxed.owl	regulation of branching involved in salivary gland morphogenesis by epithelial-mesenchymal signalling							dph	2009-06-03T06:30:56Z					biological_process											owl:Class	
GO:0043098	biolink:NamedThing	purine deoxyribonucleoside salvage	Any process which produces a purine deoxyribonucleoside from derivatives of it, without de novo synthesis.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1903771	biolink:NamedThing	positive regulation of beta-galactosidase activity	Any process that activates or increases the frequency, rate or extent of beta-galactosidase activity.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of hydrolact|up-regulation of beta-D-lactosidase activity|up-regulation of trilactase activity|positive regulation of exo-(1->4)-beta-D-galactanase activity|upregulation of beta-D-galactanase activity|upregulation of hydrolact|upregulation of lactozym|positive regulation of sumiklat|upregulation of beta-D-lactosidase activity|up-regulation of lactose hydrolysis|positive regulation of maxilact|positive regulation of hydrolact|up regulation of maxilact|activation of exo-(1->4)-beta-D-galactanase activity|up regulation of trilactase activity|up-regulation of beta-lactosidase activity|up regulation of lactozym|positive regulation of lactozym|up-regulation of maxilact|up-regulation of exo-(1->4)-beta-D-galactanase activity|activation of lactose hydrolysis|activation of sumiklat|upregulation of beta-galactosidase activity|up-regulation of lactozym|up regulation of sumiklat|activation of lactozym|positive regulation of lactose hydrolysis|upregulation of beta-lactosidase activity|up-regulation of beta-D-galactanase activity|upregulation of lactose hydrolysis|activation of beta-D-galactanase activity|positive regulation of beta-D-galactanase activity|activation of beta-D-lactosidase activity|upregulation of trilactase activity|up regulation of beta-lactosidase activity|activation of S 2107|upregulation of beta-D-galactoside galactohydrolase activity|activation of oryzatym|up-regulation of S 2107|up regulation of exo-(1->4)-beta-D-galactanase activity|positive regulation of beta-lactosidase activity|upregulation of sumiklat|up regulation of beta-D-galactoside galactohydrolase activity|up regulation of oryzatym|activation of beta-lactosidase activity|activation of trilactase activity|up regulation of beta-D-lactosidase activity|up regulation of S 2107|positive regulation of oryzatym|activation of beta-galactosidase activity|activation of maxilact|positive regulation of S 2107|up-regulation of sumiklat|positive regulation of beta-D-galactoside galactohydrolase activity|upregulation of oryzatym|activation of hydrolact|up regulation of lactose hydrolysis|upregulation of exo-(1->4)-beta-D-galactanase activity|positive regulation of trilactase activity|activation of beta-D-galactoside galactohydrolase activity|up regulation of beta-galactosidase activity|up regulation of beta-D-galactanase activity|up-regulation of oryzatym|up regulation of hydrolact|up-regulation of beta-D-galactoside galactohydrolase activity|up-regulation of beta-galactosidase activity|positive regulation of beta-D-lactosidase activity|upregulation of S 2107|upregulation of maxilact							nc	2015-01-06T10:53:32Z					biological_process											owl:Class	
GO:1902561	biolink:NamedThing	origin recognition complex assembly	The aggregation, arrangement and bonding together of a set of components to form an origin recognition complex.	tmpzr1t_l9r_go_relaxed.owl	ORC assembly|origin recognition complex formation|ORC formation|origin of replication recognition complex assembly|origin of replication recognition complex formation							mah	2013-12-10T12:11:50Z					biological_process											owl:Class	
GO:0008685	biolink:NamedThing	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity	Catalysis of the reaction: 4-CDP-2-C-methyl-D-erythritol 2-phosphate = 2-C-methyl-D-erythritol 2,4-cyclic diphosphate + CMP.	tmpzr1t_l9r_go_relaxed.owl	MECDP-synthase activity|MECP synthase activity|2-phospho-4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol CMP-lyase (cyclizing)|2-phospho-4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol CMP-lyase (cyclizing; 2-C-methyl-D-erythritol 2,4-cyclodiphosphate-forming)				EC:4.6.1.12|RHEA:23864|MetaCyc:RXN0-302|KEGG_REACTION:R05637									molecular_function											owl:Class	
GO:0032150	biolink:NamedThing	ubiquinone biosynthetic process from chorismate	The chemical reactions and pathways resulting in the formation of ubiquinone, beginning with the conversion of chorismate to 4-hydroxybenzoate.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0034444	biolink:NamedThing	regulation of plasma lipoprotein oxidation	Any process that modulates the frequency, rate or extent of lipoprotein oxidation, occurring in the blood plasma.	tmpzr1t_l9r_go_relaxed.owl	regulation of plasma lipoprotein particle oxidation													biological_process											owl:Class	
GO:0035793	biolink:NamedThing	positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway	Any process that increases the frequency, rate or extent of metanephric mesenchymal cell migration as a result of the series of molecular signals generated as a consequence of a platelet-derived growth factor receptor-beta binding to one of its physiological ligands.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of metanephric mesenchymal cell migration by PDGFR-beta signaling pathway|positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signalling pathway|positive regulation of metanephric mesenchymal cell migration by PDGF receptor-beta signaling pathway|positive regulation of metanephric mesenchymal cell migration by betaPDGF receptor signaling pathway							bf	2011-04-11T01:30:03Z					biological_process											owl:Class	
GO:2000591	biolink:NamedThing	positive regulation of metanephric mesenchymal cell migration	Any process that activates or increases the frequency, rate or extent of metanephric mesenchymal cell migration.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of metanephric mesenchyme chemotaxis							bf	2011-04-07T03:29:53Z					biological_process											owl:Class	
GO:0046035	biolink:NamedThing	CMP metabolic process	The chemical reactions and pathways involving CMP, cytidine monophosphate.	tmpzr1t_l9r_go_relaxed.owl	CMP metabolism													biological_process											owl:Class	
GO:0071976	biolink:NamedThing	cell gliding	Cell motility that results in the smooth movement of a cell along a solid surface.	tmpzr1t_l9r_go_relaxed.owl	cell gliding motility							mah	2010-10-21T02:33:24Z					biological_process											owl:Class	
GO:0031489	biolink:NamedThing	myosin V binding	Binding to a class V myosin; myosin V is a dimeric molecule involved in intracellular transport.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0098625	biolink:NamedThing	methylselenol reductase activity	Catalysis of the reaction: NADPH + H+ + CH3SeOH => NADP+ + CH3SeH + H2O.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-5263614									molecular_function											owl:Class	
GO:0000700	biolink:NamedThing	mismatch base pair DNA N-glycosylase activity	Catalysis of the removal of single bases present in mismatches by the cleavage the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar. The reaction releases a free base and leaves an apurinic/apyrimidinic (AP) site.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0097702	biolink:NamedThing	response to oscillatory fluid shear stress	Any response to fluid shear stress where the fluid is moving across a solid surface with an oscillatory flow. Disturbed flow patterns at the arterial bifurcations and curvatures may cause endothelial dysfunction, which initiates atherosclerosis.	tmpzr1t_l9r_go_relaxed.owl								pr	2016-01-27T14:17:08Z					biological_process											owl:Class	
GO:0085041	biolink:NamedThing	arbuscule	Highly branched symbiont haustoria within host root cortex cells, responsible for nutrient exchange.	tmpzr1t_l9r_go_relaxed.owl						See also: periarbuscular membrane ; GO:0085042.		jl	2010-07-27T04:29:03Z					cellular_component											owl:Class	
GO:0085035	biolink:NamedThing	haustorium	A projection from a cell or tissue that penetrates the host's cell wall and invaginates the host cell membrane.	tmpzr1t_l9r_go_relaxed.owl						See also: extrahaustorial matrix ; GO:0085036 and extrahaustorial membrane ; GO:0085037.		jl	2010-07-27T03:42:24Z					cellular_component											owl:Class	
GO:0047043	biolink:NamedThing	3-alpha-hydroxycholanate dehydrogenase activity	Catalysis of the reaction: lithocholate + NAD(+) = 3-oxo-5beta-cholanate + H(+) + NADH.	tmpzr1t_l9r_go_relaxed.owl	3alpha-hydroxycholanate dehydrogenase activity|alpha-hydroxy-cholanate dehydrogenase activity|3alpha-hydroxy-5beta-cholanate:NAD+ oxidoreductase activity				KEGG_REACTION:R04139|MetaCyc:1.1.1.52-RXN|EC:1.1.1.52|RHEA:19585									molecular_function											owl:Class	
GO:0071293	biolink:NamedThing	cellular response to tellurium ion	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tellurium ion stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to tellurium							mah	2009-12-10T04:16:52Z					biological_process											owl:Class	
GO:0046690	biolink:NamedThing	response to tellurium ion	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tellurium ion stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to tellurium|tellurium sensitivity/resistance													biological_process											owl:Class	
GO:0098643	biolink:NamedThing	banded collagen fibril	A supramolecular assembly of fibrillar collagen complexes in the form of a long fiber (fibril) with transverse striations (bands).	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:1901242	biolink:NamedThing	ABC-type doxorubicin transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + doxorubicin(in) = ADP + phosphate + doxorubicin(out).	tmpzr1t_l9r_go_relaxed.owl	doxorubicin transmembrane-transporting ATPase activity|ATPase-coupled doxorubicin transmembrane transporter activity				TC:3.A.1.105.1			jl	2012-08-07T15:10:13Z					molecular_function											owl:Class	
GO:0006173	biolink:NamedThing	dADP biosynthetic process	The chemical reactions and pathways resulting in the formation of dADP, deoxyadenosine diphosphate (2'-deoxyadenosine 5'-diphosphate).	tmpzr1t_l9r_go_relaxed.owl	dADP synthesis|dADP biosynthesis|dADP anabolism|dADP formation													biological_process											owl:Class	
GO:0045741	biolink:NamedThing	positive regulation of epidermal growth factor-activated receptor activity	Any process that activates or increases the frequency, rate or extent of EGF-activated receptor activity.	tmpzr1t_l9r_go_relaxed.owl	upregulation of epidermal growth factor receptor activity|up-regulation of epidermal growth factor receptor activity|positive regulation of EGFR activity|positive regulation of EGF receptor activity|stimulation of epidermal growth factor receptor activity|positive regulation of epidermal growth factor receptor activity|up regulation of epidermal growth factor receptor activity|activation of epidermal growth factor receptor activity													biological_process											owl:Class	
GO:0062191	biolink:NamedThing	galactoxylomannan biosynthetic process	The chemical reactions and pathways resulting in the formation of the exopolysaccharide galactoxylomannan. Galactoxylomannan is produced by a pathogenic fungus and causes paralysis in some animals.	tmpzr1t_l9r_go_relaxed.owl	glucuronoxylomannogalactan biosynthetic process|galactoxylomannan formation|galactoxylomannan synthesis|galactoxylomannan biosynthesis|galactoxylomannan anabolism|GalXM biosynthetic process							dph	2019-12-06T14:44:36Z					biological_process											owl:Class	
GO:0047518	biolink:NamedThing	1-methyladenosine nucleosidase activity	Catalysis of the reaction: 1-methyladenosine + H(2)O = 1-methyladenine + ribofuranose.	tmpzr1t_l9r_go_relaxed.owl	1-methyladenosine ribohydrolase activity|1-methyladenosine hydrolase activity				MetaCyc:1-METHYLADENOSINE-NUCLEOSIDASE-RXN|RHEA:12865|EC:3.2.2.13|KEGG_REACTION:R03885									molecular_function											owl:Class	
GO:0007554	biolink:NamedThing	regulation of ecdysteroid biosynthetic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of ecdysteroids.	tmpzr1t_l9r_go_relaxed.owl	regulation of ecdysteroid anabolism|regulation of ecdysteroid synthesis|regulation of ecdysteroid biosynthesis|regulation of ecdysteroid formation													biological_process											owl:Class	
GO:0050948	biolink:NamedThing	positive regulation of early stripe melanocyte differentiation	Any process that activates or increases the frequency, rate or extent of early stripe melanocyte differentiation.	tmpzr1t_l9r_go_relaxed.owl	up regulation of early stripe melanocyte differentiation|upregulation of early stripe melanocyte differentiation|stimulation of early stripe melanocyte differentiation|activation of early stripe melanocyte differentiation|up-regulation of early stripe melanocyte differentiation|positive regulation of early stripe melanophore differentiation													biological_process											owl:Class	
GO:0070692	biolink:NamedThing	CTDK-1 complex	A positive transcription elongation factor complex that comprises the CDK kinase CTK1 (in budding yeast), Lsk1 (in fission yeast) (corresponding to the Panther PTHR24056:SF39 family), a cyclin and an additional gamma subunit (corresponding to the InterPRO entry IPR024638).	tmpzr1t_l9r_go_relaxed.owl	Ctk complex|CTDK-I complex|C-terminal domain kinase I complex|trimeric positive transcription elongation factor complex b							mah	2009-06-03T03:18:04Z					cellular_component											owl:Class	
GO:0120221	biolink:NamedThing	maintenance of ciliary planar beating movement pattern	Any process involved in maintaining the planar beating pattern of ciliary movement pattern. Connection between the outer doublets and the central pair via the radial spokes constrains ciliary movement to the planar beating pattern. Cilia that lack this connection, such as those in the embryonic node or Kupfer's vesicle, display radial movement.	tmpzr1t_l9r_go_relaxed.owl						Note that we deem cilium and microtubule-based flagellum to be equivalent.		krc	2019-12-10T21:34:54Z					biological_process											owl:Class	
GO:0018291	biolink:NamedThing	molybdenum incorporation into iron-sulfur cluster	The incorporation of molybdenum into an iron-sulfur cluster.	tmpzr1t_l9r_go_relaxed.owl	molybdenum incorporation into iron-sulphur cluster													biological_process											owl:Class	
GO:0032577	biolink:NamedThing	phosphatidylcholine:cardiolipin O-linoleoyltransferase activity	Catalysis of the transfer of a linoleoyl ((9Z,12Z)-octadeca-9,12-dienoyl) group from phosphatidylcholine to an oxygen atom on a cardiolipin molecule.	tmpzr1t_l9r_go_relaxed.owl	phosphatidylcholine:cardiolipin linoleoyltransferase													molecular_function											owl:Class	
GO:0018520	biolink:NamedThing	cis-1,2-dihydroxy-4-methylcyclohexa-3,5-diene-1-carboxylate dehydrogenase activity	Catalysis of the reaction: cis-1,2-dihydroxy-4-methylcyclohexa-3,5-diene-1-carboxylate + NADP+ = 4-methylcatechol + NADPH + H+ + CO2.	tmpzr1t_l9r_go_relaxed.owl	cis-1,2-dihydroxy-4-methylcyclohexa-3,5-diene-1-carboxylate:NAD(P)+ oxidoreductase (decarboxylating)|4-methylcyclohexa-3,5-diene-1,2-cis-diol-1-carboxylic acid dehydrogenase activity				UM-BBD_reactionID:r0179|EC:1.3.1.67|MetaCyc:1.3.1.67-RXN									molecular_function											owl:Class	
GO:0103104	biolink:NamedThing	6-methylthiohexyldesulfoglucosinolate sulfotransferase activity	Catalysis of the reaction: 6-methylthiohexyldesulfoglucosinolate + 3'-phosphonato-5'-adenylyl sulfate <=> adenosine 3',5'-bismonophosphate + H+ + 6-methylthiohexylglucosinolate.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXNQT-4331									molecular_function											owl:Class	
GO:0003172	biolink:NamedThing	sinoatrial valve development	The progression of the sinoatrial valve over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl	SA valve development							dph	2009-10-08T11:15:39Z					biological_process											owl:Class	
GO:0060107	biolink:NamedThing	annuli extracellular matrix	The extracellular matrix that is a regularly spaced circumferential ridge present in the cortical region of the cuticle. Annuli are delineated by annular furrows and are present throughout the cuticle with the exception of lateral regions where longitudinal alae are present.	tmpzr1t_l9r_go_relaxed.owl	annular rings|annule(s)|annulae|annulus													cellular_component											owl:Class	
GO:0071165	biolink:NamedThing	GINS complex assembly	The aggregation, arrangement and bonding together of a set of components to form a GINS complex, a heterotetrameric protein complex that associates with DNA replication origins and replication forks.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-11-19T03:37:20Z					biological_process											owl:Class	
GO:2000654	biolink:NamedThing	regulation of cellular response to testosterone stimulus	Any process that modulates the frequency, rate or extent of cellular response to testosterone stimulus.	tmpzr1t_l9r_go_relaxed.owl								vk	2011-05-02T03:23:56Z					biological_process											owl:Class	
GO:0106160	biolink:NamedThing	negative regulation of small RNA loading onto RISC	Any process that stops, prevents or reduces the frequency, rate or extent of small RNA loading onto RISC.	tmpzr1t_l9r_go_relaxed.owl								hjd	2018-11-30T15:42:16Z					biological_process											owl:Class	
GO:0043643	biolink:NamedThing	tetracycline metabolic process	The chemical reactions and pathways involving tetracycline, (4S,4aS,5aS,6S,12aS)-4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide, a broad-spectrum antibiotic produced by streptomyces bacteria that blocks binding of aminoacyl tRNA to the ribosomes of both Gram-positive and Gram-negative organisms (and those of organelles).	tmpzr1t_l9r_go_relaxed.owl	tetracycline metabolism|tetracyclin metabolic process|tetracyclin metabolism													biological_process											owl:Class	
GO:0032158	biolink:NamedThing	septin band	A diffuse ring composed of a series of septin bars that run parallel to the long axis of the cell. This type of septin structure has been observed in a number of locations associated with polarized grown and/or deposition of new membrane, but not with cytokinesis, such as at the shmoo (mating projection) neck, at the junction between the mother cell and the germ tube (hypha) of a fungal cell growing filamentously.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:1901279	biolink:NamedThing	D-ribose 5-phosphate catabolic process	The chemical reactions and pathways resulting in the breakdown of D-ribose 5-phosphate.	tmpzr1t_l9r_go_relaxed.owl	D-ribose 5-phosphate breakdown|D-ribose 5-phosphate degradation|D-ribose 5-phosphate catabolism							yaf	2012-08-17T15:00:19Z					biological_process											owl:Class	
GO:0102381	biolink:NamedThing	stevioside glucosyltransferase activity (rebaudioside A forming)	Catalysis of the reaction: stevioside + UDP-alpha-D-glucose = rebaudioside A + UDP + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-13517									molecular_function											owl:Class	
GO:0050518	biolink:NamedThing	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity	Catalysis of the reaction: 2-C-methyl-D-erythritol 4-phosphate + CTP = 4-CDP-2-C-methyl-D-erythritol + diphosphate.	tmpzr1t_l9r_go_relaxed.owl	CTP:2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity|MCT activity|4-diphosphocytidyl-2C-methyl-D-erythritol synthase activity|4-diphosphocytidyl-2-C-methyl-D-erythritol synthase activity|MEP cytidylyltransferase activity				KEGG_REACTION:R05633|MetaCyc:2.7.7.60-RXN|RHEA:13429|EC:2.7.7.60							GO:0008699		molecular_function											owl:Class	
GO:0099016	biolink:NamedThing	DNA end degradation evasion by virus	A process by which a virus evades and ends degradation of its DNA when free viral-DNA ends are exposed as part of its life-cycle. For example, some bacteriophages encode proteins that bind to free viral DNA ends, protecting them from degradation by host exonucleases.	tmpzr1t_l9r_go_relaxed.owl					VZ:3963									biological_process											owl:Class	
GO:0019673	biolink:NamedThing	GDP-mannose metabolic process	The chemical reactions and pathways involving GDP-mannose, a substance composed of mannose in glycosidic linkage with guanosine diphosphate.	tmpzr1t_l9r_go_relaxed.owl	GDP-mannose metabolism													biological_process											owl:Class	
GO:0033010	biolink:NamedThing	paranodal junction	A highly specialized cell-cell junction found in vertebrates, which forms between a neuron and a glial cell, and has structural similarity to Drosophila septate junctions. It flanks the node of Ranvier in myelinated nerve and electrically isolates the myelinated from unmyelinated nerve segments and physically separates the voltage-gated sodium channels at the node from the cluster of potassium channels underneath the myelin sheath.	tmpzr1t_l9r_go_relaxed.owl	paranodal axoglial junction|axoglial septate junction|paranodal septate junction													cellular_component											owl:Class	
GO:0102857	biolink:NamedThing	1-18:1-2-18:3-phosphatidylcholinedesaturase activity	Catalysis of the reaction: 1-18:1-2-18:3-phosphatidylcholine + O2 + a reduced electron acceptor <=> 1-18:2-2-18:3-phosphatidylcholine + 2 H2O + an oxidized electron acceptor.	tmpzr1t_l9r_go_relaxed.owl					EC:1.14.19.22|MetaCyc:RXN-8324									molecular_function											owl:Class	
GO:0102369	biolink:NamedThing	11alpha-30-dihydroxy beta-amyrin dehydrogenase activity	Catalysis of the reaction: 11alpha,30-dihydroxy-beta-amyrin + NADPH + O2 + H+ <=> 30-hydroxy-11-oxo-beta-amyrin + NADP + 2 H2O.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-13491									molecular_function											owl:Class	
GO:1901399	biolink:NamedThing	negative regulation of transforming growth factor beta3 activation	Any process that stops, prevents or reduces the frequency, rate or extent of transforming growth factor beta3 activation.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of TGFbeta 3 activation|negative regulation of TGFB3 activation|down regulation of TGFbeta 3 activation|down regulation of TGF-beta 3 activation|down-regulation of TGFB3 activation|down-regulation of transforming growth factor beta3 activation|downregulation of TGFB3 activation|down-regulation of TGFbeta 3 activation|downregulation of TGF-beta 3 activation|downregulation of transforming growth factor beta3 activation|inhibition of TGFB3 activation|down regulation of TGFB3 activation|down-regulation of TGF-beta 3 activation|inhibition of transforming growth factor beta3 activation|inhibition of TGFbeta 3 activation|inhibition of TGF-beta 3 activation|negative regulation of TGF-beta 3 activation|downregulation of TGFbeta 3 activation|down regulation of transforming growth factor beta3 activation							bf	2012-10-01T10:50:32Z					biological_process											owl:Class	
GO:0043969	biolink:NamedThing	histone H2B acetylation	The modification of histone H2B by the addition of an acetyl group.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0050233	biolink:NamedThing	pyranose oxidase activity	Catalysis of the reaction: D-glucose + O(2) = 2-dehydro-D-glucose + H(2)O(2).	tmpzr1t_l9r_go_relaxed.owl	pyranose:oxygen 2-oxidoreductase activity|pyranose-2-oxidase activity|glucose 2-oxidase activity				MetaCyc:PYRANOSE-OXIDASE-RXN|KEGG_REACTION:R00302|RHEA:10552|EC:1.1.3.10									molecular_function											owl:Class	
GO:0010126	biolink:NamedThing	mycothiol metabolic process	The chemical reactions and pathways involving mycothiol, which consists of N-acetyl-L-cysteine linked to a pseudodisaccharide, D-glucosamine and myo-inositol. Mycothiol is produced in actinomycetes like mycobacteria and serves similar functions to glutathione.	tmpzr1t_l9r_go_relaxed.owl	mycothiol metabolism													biological_process											owl:Class	
GO:0048370	biolink:NamedThing	lateral mesoderm formation	The process that gives rise to the lateral mesoderm. This process pertains to the initial formation of the structure from unspecified parts.	tmpzr1t_l9r_go_relaxed.owl	lateral plate mesoderm biosynthesis|lateral plate mesoderm formation													biological_process											owl:Class	
GO:0097096	biolink:NamedThing	facial suture morphogenesis	The process in which any suture between facial bones is generated and organized.	tmpzr1t_l9r_go_relaxed.owl								pr	2011-07-05T03:06:27Z					biological_process											owl:Class	
GO:0150053	biolink:NamedThing	cerebellar climbing fiber to Purkinje cell synapse	A synapse of a climbing fiber onto the dendrites of a Purkinje cell in cerebellum. The climbing fiber originates from the inferior olivary nucleus of the medulla oblongata.	tmpzr1t_l9r_go_relaxed.owl	cerebellar climbing fibre to Purkinje cell synapse							bc	2018-05-09T09:57:20Z					cellular_component											owl:Class	
GO:0035765	biolink:NamedThing	motor neuron precursor migration involved in dorsal motor nucleus of vagus nerve formation	The orderly movement of a motor neuron precursor cell that contributes to formation of the dorsal motor nucleus of the vagus nerve.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-03-29T02:52:09Z					biological_process											owl:Class	
GO:0010477	biolink:NamedThing	response to sulfur dioxide	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sulfur dioxide (SO2) stimulus.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0047139	biolink:NamedThing	glutathione-homocystine transhydrogenase activity	Catalysis of the reaction: homocystine + 2 reduced glutathione = oxidized glutathione + 2 homocysteine.	tmpzr1t_l9r_go_relaxed.owl	glutathione:homocystine oxidoreductase activity				EC:1.8.4.1|RHEA:11464|MetaCyc:1.8.4.1-RXN									molecular_function											owl:Class	
GO:0016159	biolink:NamedThing	muconolactone delta-isomerase activity	Catalysis of the reaction: 2,5-dihydro-5-oxofuran-2-acetate = 3,4-dihydro-5-oxofuran-2-acetate.	tmpzr1t_l9r_go_relaxed.owl	muconolactone D-isomerase activity|muconolactone isomerase activity|5-oxo-4,5-dihydrofuran-2-acetate delta3-delta2-isomerase activity				EC:5.3.3.4|RHEA:12348|MetaCyc:MUCONOLACTONE-DELTA-ISOMERASE-RXN									molecular_function											owl:Class	
GO:1902209	biolink:NamedThing	negative regulation of bacterial-type flagellum assembly	Any process that stops, prevents or reduces the frequency, rate or extent of bacterial-type flagellum assembly.	tmpzr1t_l9r_go_relaxed.owl	inhibition of bacterial flagellum assembly|downregulation of bacterial flagellum assembly|down-regulation of bacterial-type flagellum assembly|negative regulation of bacterial flagellum assembly|down-regulation of bacterial flagellum assembly|down regulation of bacterial-type flagellum assembly|down regulation of bacterial flagellum assembly|inhibition of bacterial-type flagellum assembly|downregulation of bacterial-type flagellum assembly							jl	2013-06-11T14:20:24Z					biological_process											owl:Class	
GO:0034775	biolink:NamedThing	glutathione transmembrane transport	A process in which glutathione is transported across a membrane.	tmpzr1t_l9r_go_relaxed.owl	transmembrane glutathione transport|glutathione membrane transport					Note that this term is not intended for use in annotating lateral movement within membranes.								biological_process											owl:Class	
GO:0098812	biolink:NamedThing	nuclear rRNA polyadenylation involved in polyadenylation-dependent rRNA catabolic process	The enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end of a rRNA, occurring as part of the process of polyadenylation-dependent rRNA catabolism in the nucleus.	tmpzr1t_l9r_go_relaxed.owl	nuclear rRNA polyadenylation involved in poly(A)-dependent rRNA catabolic process|nuclear rRNA polyadenylation during polyadenylation-dependent rRNA catabolic process													biological_process											owl:Class	
GO:0075506	biolink:NamedThing	entry of viral genome into host nucleus through nuclear pore complex via importin	Viral penetration into the host nucleus where the viral genome passes through the nuclear pore complex (NPC) using the cellular importin transport machinery.	tmpzr1t_l9r_go_relaxed.owl	entry of viral genome into host nucleus via cellular importin transport through the nuclear pore complex					This mechanism is used by some RNA viruses (e.g. Orthomyxoviridae), some dsDNA viruses (e.g. Polyomaviridae) and some ssRNA viruses (e.g. Lentivirus).		jl	2011-07-26T04:36:46Z					biological_process											owl:Class	
GO:0010161	biolink:NamedThing	red light signaling pathway	The series of molecular signals initiated upon sensing of red light by a photoreceptor molecule. Red light is electromagnetic radiation of wavelength of 580-700nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reversed by exposure to far red light. During the initial phase the phytochrome molecule is only present in the red light absorbing form, but on absorption of red light it changes to a far red light absorbing form, triggering progress through development. An immediate short period of exposure to far red light entirely returns the pigment to its initial state and prevents triggering of the developmental process. A thirty minute break between red and subsequent far red light exposure renders the red light effect irreversible, and development then occurs regardless of whether far red light exposure subsequently occurs.	tmpzr1t_l9r_go_relaxed.owl	red light signal transduction|red light signalling pathway|red light phototransduction													biological_process											owl:Class	
GO:0043406	biolink:NamedThing	positive regulation of MAP kinase activity	Any process that activates or increases the frequency, rate or extent of MAP kinase activity.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of mitogen-activated protein kinase activity|positive regulation of mitogen activated protein kinase activity|upregulation of MAPK activity|up-regulation of MAPK activity|stimulation of MAPK activity|up regulation of MAPK activity													biological_process											owl:Class	
GO:0140654	biolink:NamedThing	tryprostatin A biosynthetic process	The chemical reactions and pathways resulting in the formation of tryprostatin A.	tmpzr1t_l9r_go_relaxed.owl	tryprostatin A biosynthesis|tryprostatin A anabolism|tryprostatin A synthesis|tryprostatin A formation	https://github.com/geneontology/go-ontology/issues/21495						pg	2021-05-27T08:39:56Z					biological_process											owl:Class	
GO:0150048	biolink:NamedThing	cerebellar granule cell to Purkinje cell synapse	A synapse of a granule cell fiber onto the dendrites of a Purkinje cell in cerebellum.	tmpzr1t_l9r_go_relaxed.owl	cerebellar parallel fiber to Purkinje cell synapse							bc	2018-04-23T14:44:40Z					cellular_component											owl:Class	
GO:0047409	biolink:NamedThing	alkenylglycerophosphoethanolamine hydrolase activity	Catalysis of the reaction: H2O + 1-(1-alkenyl)-sn-glycero-3-phosphoethanolamine = sn-glycero-3-phosphoethanolamine + an aldehyde.	tmpzr1t_l9r_go_relaxed.owl	1-(1-alkenyl)-sn-glycero-3-phosphoethanolamine aldehydohydrolase activity				EC:3.3.2.5|RHEA:16905|MetaCyc:3.3.2.5-RXN									molecular_function											owl:Class	
GO:0009097	biolink:NamedThing	isoleucine biosynthetic process	The chemical reactions and pathways resulting in the formation of isoleucine, (2R*,3R*)-2-amino-3-methylpentanoic acid.	tmpzr1t_l9r_go_relaxed.owl	isoleucine anabolism|isoleucine formation|isoleucine synthesis|isoleucine biosynthesis				MetaCyc:ILEUSYN-PWY									biological_process											owl:Class	
GO:0009624	biolink:NamedThing	response to nematode	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a nematode.	tmpzr1t_l9r_go_relaxed.owl	response to nematodes													biological_process											owl:Class	
GO:0061658	biolink:NamedThing	URM1 conjugating enzyme activity	Isoenergetic transfer of URM1 from one protein to another via the reaction X-URM1 + Y -> Y-URM1 + X, where both the X-URM1 and Y-URM1 linkages are thioester bonds between the C-terminal amino acid of URM1 and a sulfhydryl side group of a cysteine residue.	tmpzr1t_l9r_go_relaxed.owl	E2							dph	2014-11-06T13:37:26Z					molecular_function											owl:Class	
GO:0042294	biolink:NamedThing	URM1 transferase activity	Catalysis of the transfer of URM1 from one protein to another via the reaction X-URM1 + Y --> Y-URM1 + X, where both X-URM1 and Y-URM1 are covalent linkages.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0030573	biolink:NamedThing	bile acid catabolic process	The chemical reactions and pathways resulting in the breakdown of bile acids, any of a group of steroid carboxylic acids occurring in bile.	tmpzr1t_l9r_go_relaxed.owl	cholate catabolic process|bile acid degradation|bile acid catabolism|bile acid breakdown|bile acid 7alpha-dehydroxylation pathway				MetaCyc:7ALPHADEHYDROX-PWY							GO:0019613		biological_process											owl:Class	
GO:0047669	biolink:NamedThing	amylosucrase activity	Catalysis of the reaction: sucrose + 1,4-alpha-D-glucosyl(n) = D-fructose + 1,4-alpha-D-glucosyl(n+1).	tmpzr1t_l9r_go_relaxed.owl	sucrose-1,4-alpha-glucan glucosyltransferase activity|sucrose:1,4-alpha-D-glucan 4-alpha-D-glucosyltransferase activity|sucrose-glucan glucosyltransferase activity				RHEA:24572|MetaCyc:AMYLOSUCRASE-RXN|EC:2.4.1.4									molecular_function											owl:Class	
GO:0032122	biolink:NamedThing	oral apparatus organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the oral apparatus. The oral apparatus is a funnel-like structure used by the cell to collect food and channel it to the cytostome, characteristic of ciliate protozoans.	tmpzr1t_l9r_go_relaxed.owl	oral apparatus organisation|oral apparatus morphogenesis|stomatogenesis|oral apparatus organization and biogenesis													biological_process											owl:Class	
GO:0043731	biolink:NamedThing	6-hydroxynicotinate 3-monooxygenase activity	Catalysis of the oxidative decarboxylation of 6-hydroxynicotinate to 2,5-dihydroxypyridine, dependent on O2, NADH +H+ and FAD.	tmpzr1t_l9r_go_relaxed.owl					EC:1.14.13.114|RHEA:27333|MetaCyc:RXN-7573									molecular_function											owl:Class	
GO:0060290	biolink:NamedThing	transdifferentiation	The conversion of a differentiated cell of one fate into a differentiated cell of another fate without first undergoing cell division or reversion to a more primitive or stem cell-like fate.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Transdifferentiation									biological_process											owl:Class	
GO:0042758	biolink:NamedThing	long-chain fatty acid catabolic process	The chemical reactions and pathways resulting in the breakdown of long-chain fatty acids, a fatty acid with a chain length between C13 and C22.	tmpzr1t_l9r_go_relaxed.owl	long-chain fatty acid degradation|long-chain fatty acid catabolism|long-chain fatty acid breakdown													biological_process											owl:Class	
GO:0008609	biolink:NamedThing	alkylglycerone-phosphate synthase activity	Catalysis of the reaction: 1-acyl-glycerone 3-phosphate + a long-chain alcohol = 1-alkyl-glycerone 3-phosphate + a long-chain acid anion.	tmpzr1t_l9r_go_relaxed.owl	1-acyl-glycerone-3-phosphate:long-chain-alcohol O-3-phospho-2-oxopropanyltransferase activity|alkyl DHAP synthetase activity|alkyl-DHAP synthase activity|dihydroxyacetone-phosphate acyltransferase activity|alkyldihydroxyacetone phosphate synthetase activity|alkyldihydroxyacetonephosphate synthase activity|alkyl-DHAP|DHAP-AT				MetaCyc:ALKYLGLYCERONE-PHOSPHATE-SYNTHASE-RXN|RHEA:36171|EC:2.5.1.26|Reactome:R-HSA-390427									molecular_function											owl:Class	
GO:0009127	biolink:NamedThing	purine nucleoside monophosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of purine nucleoside monophosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with phosphate on the sugar.	tmpzr1t_l9r_go_relaxed.owl	purine nucleoside monophosphate formation|purine nucleoside monophosphate anabolism|purine nucleoside monophosphate synthesis|purine nucleoside monophosphate biosynthesis													biological_process											owl:Class	
GO:0047337	biolink:NamedThing	dolichyl-diphosphate-polyphosphate phosphotransferase activity	Catalysis of the reaction: dolichyl diphosphate + long-chain-polyphosphate = dolichol-phosphate + long-chain-polyphosphate.	tmpzr1t_l9r_go_relaxed.owl	dolichylpyrophosphate:polyphosphate phosphotransferase activity|dolichyl-diphosphate:polyphosphate phosphotransferase activity				RHEA:19417|MetaCyc:2.7.4.20-RXN|EC:2.7.4.20									molecular_function											owl:Class	
GO:0070712	biolink:NamedThing	RNA cytidine-uridine insertion	The modification of an RNA molecule by insertion of an cytidine-uridine dinucleotide.	tmpzr1t_l9r_go_relaxed.owl	RNA CU insertion							mah	2009-06-08T05:27:01Z					biological_process											owl:Class	
GO:0021853	biolink:NamedThing	cerebral cortex GABAergic interneuron migration	The migration of GABAergic interneuron precursors from the subpallium to the cerebral cortex.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0102077	biolink:NamedThing	oleamide hydrolase activity	Catalysis of the reaction: oleamide + H2O <=> oleate + ammonium.	tmpzr1t_l9r_go_relaxed.owl					EC:3.5.1.99|RHEA:26506|MetaCyc:RXN-10756									molecular_function											owl:Class	
GO:0102779	biolink:NamedThing	cannabidiolate synthase activity	Catalysis of the reaction: cannabigerolate + O2 <=> cannabidiolate + hydrogen peroxide.	tmpzr1t_l9r_go_relaxed.owl					RHEA:34411|EC:1.21.3.8|MetaCyc:RXN-7855									molecular_function											owl:Class	
GO:0018310	biolink:NamedThing	protein-FMN linkage via S-(6-FMN)-L-cysteine	The formation of a protein-FMN linkage via S-(6-FMN)-L-cysteine.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0220									biological_process											owl:Class	
GO:0036505	biolink:NamedThing	prosaposin receptor activity	Combining with prosaposin to initiate a change in cell activity. Prosaposin is the glycoprotein precursor of four cleavage products (saposins A, B, C and D).	tmpzr1t_l9r_go_relaxed.owl	prosaposin-activated receptor activity							bf	2015-06-11T10:13:10Z					molecular_function											owl:Class	
GO:1901543	biolink:NamedThing	negative regulation of ent-pimara-8(14),15-diene biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of ent-pimara-8(14),15-diene biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	down regulation of ent-pimara-8(14),15-diene anabolism|negative regulation of ent-pimara-8(14),15-diene formation|inhibition of ent-pimara-8(14),15-diene formation|down-regulation of ent-pimara-8(14),15-diene biosynthesis|down-regulation of ent-pimara-8(14),15-diene anabolism|down-regulation of ent-pimara-8(14),15-diene formation|inhibition of ent-pimara-8(14),15-diene biosynthesis|downregulation of ent-pimara-8(14),15-diene anabolism|inhibition of ent-pimara-8(14),15-diene anabolism|down regulation of ent-pimara-8(14),15-diene biosynthesis|down regulation of ent-pimara-8(14),15-diene synthesis|inhibition of ent-pimara-8(14),15-diene biosynthetic process|negative regulation of ent-pimara-8(14),15-diene anabolism|negative regulation of ent-pimara-8(14),15-diene synthesis|negative regulation of ent-pimara-8(14),15-diene biosynthesis|downregulation of ent-pimara-8(14),15-diene biosynthesis|down-regulation of ent-pimara-8(14),15-diene biosynthetic process|downregulation of ent-pimara-8(14),15-diene formation|down-regulation of ent-pimara-8(14),15-diene synthesis|inhibition of ent-pimara-8(14),15-diene synthesis|down regulation of ent-pimara-8(14),15-diene formation|downregulation of ent-pimara-8(14),15-diene biosynthetic process|downregulation of ent-pimara-8(14),15-diene synthesis|down regulation of ent-pimara-8(14),15-diene biosynthetic process							di	2012-10-26T11:37:58Z					biological_process											owl:Class	
GO:0106361	biolink:NamedThing	protein-arginine rhamnosyltransferase activity	Catalysis of the reaction: dTDP-beta-L-rhamnose + L-arginyl-[protein] = dTDP + H(+) + N(omega)-(L-rhamnosyl)-L-arginyl-[protein].	tmpzr1t_l9r_go_relaxed.owl					RHEA:66692			hjd	2021-02-05T15:39:52Z					molecular_function											owl:Class	
GO:0044194	biolink:NamedThing	cytolytic granule	A specialized secretory lysosome that is present in cells with cytolytic capability such as cytotoxic T lymphocytes and natural killer cells. Cytolytic granules mediate the storage and regulated excretion of lytic molecules for killing of target cells.	tmpzr1t_l9r_go_relaxed.owl								jl	2009-10-20T01:22:13Z					cellular_component											owl:Class	
GO:2000348	biolink:NamedThing	regulation of CD40 signaling pathway	Any process that modulates the frequency, rate or extent of signaling via the CD40 signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	regulation of CD40 signalling pathway							mah	2011-02-03T10:29:40Z					biological_process											owl:Class	
GO:0047225	biolink:NamedThing	acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity	Catalysis of the reaction: N-acetyl-beta-D-glucosaminyl-1,3-N-acetyl-D-galactosaminyl-R + UDP-N-acetyl-D-glucosamine = N-acetyl-beta-D-glucosaminyl-1,6-(N-acetyl-beta-D-glucosaminyl-1,3)-N-acetyl-D-galactosaminyl-R + UDP.	tmpzr1t_l9r_go_relaxed.owl	core 4 beta6-GalNAc-transferase activity|uridine diphosphoacetylglucosamine-mucin beta(1->6)-acetylglucosaminyltransferase B|O-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase IV activity|UDP-N-acetyl-D-glucosamine:O-oligosaccharide-glycoprotein (N-acetyl-D-glucosamine to N-acetyl-D-galactosamine of N-acetyl-beta-D-glucosaminyl-1,3-N-acetyl-D-galactosaminyl-R) beta-1,6-N-acetyl-D-glucosaminyltransferase activity|core 6beta-GalNAc-transferase B|core 6-beta-GalNAc-transferase B activity				MetaCyc:2.4.1.148-RXN|EC:2.4.1.148									molecular_function											owl:Class	
GO:0098851	biolink:NamedThing	double-stranded miRNA binding	Binding to double-stranded miRNA. double-stranded miRNA is formed by processing of pre-miRNA stem-loop structures.	tmpzr1t_l9r_go_relaxed.owl	miRNA duplex binding													molecular_function											owl:Class	
GO:0003725	biolink:NamedThing	double-stranded RNA binding	Binding to double-stranded RNA.	tmpzr1t_l9r_go_relaxed.owl	dsRNA binding													molecular_function											owl:Class	
GO:0001068	biolink:NamedThing	transcription regulatory region RNA binding	Binding to a RNA region within the transcript that regulates the transcription of a gene, cistron, or operon.	tmpzr1t_l9r_go_relaxed.owl								krc	2010-10-21T04:15:32Z					molecular_function											owl:Class	
GO:0007174	biolink:NamedThing	epidermal growth factor catabolic process	The chemical reactions and pathways resulting in the breakdown of epidermal growth factor (EGF), following internalization of the receptor-bound ligand into the signal-receiving cell. Full breakdown of epidermal growth factor results in a ligand that is unable to bind and activate its receptor.	tmpzr1t_l9r_go_relaxed.owl	EGF breakdown|receptor-mediated EGF processing|epidermal growth factor ligand processing|intracellular EGF processing|epidermal growth factor catabolism|epidermal growth factor breakdown|EGF receptor ligand processing|EGF catabolism					This term describes the breakdown of epidermal growth factor within the cell, following internalization. For proteolysis events that result in the maturation of an epidermal growth factor receptor ligand, see 'epidermal growth factor receptor ligand maturation ; GO:'.								biological_process											owl:Class	
GO:0009046	biolink:NamedThing	zinc D-Ala-D-Ala carboxypeptidase activity	Catalysis of the cleavage of the D-alanyl-D-alanine bond in (Ac)2-L-lysyl-D-alanyl-D-alanine.	tmpzr1t_l9r_go_relaxed.owl	Zn2+ G peptidase activity|D-alanyl-D-alanine-cleaving carboxypeptidase activity|DD-carboxypeptidase-transpeptidase activity|DD-carboxypeptidase|G enzyme|Zn(2+) G peptidase activity|D-alanyl-D-alanine hydrolase activity				MetaCyc:3.4.17.14-RXN|EC:3.4.17.14									molecular_function											owl:Class	
GO:1902025	biolink:NamedThing	nitrate import	The directed movement of nitrate into a cell or organelle.	tmpzr1t_l9r_go_relaxed.owl	nitrate influx|nitrate uptake							tb	2013-03-27T21:32:58Z					biological_process											owl:Class	
GO:1905153	biolink:NamedThing	regulation of membrane invagination	Any process that modulates the frequency, rate or extent of membrane invagination.	tmpzr1t_l9r_go_relaxed.owl								bf	2016-04-18T15:43:54Z					biological_process											owl:Class	
GO:0052589	biolink:NamedThing	malate dehydrogenase (menaquinone) activity	Catalysis of the reaction: (S)-malate + a menaquinone = oxaloacetate + a menaquinol.	tmpzr1t_l9r_go_relaxed.owl	(S)-malate:menaquinone oxidoreductase activity|(S)-malate:(menaquinone) oxidoreductase activity				MetaCyc:RXNI-3|EC:1.1.5.4									molecular_function											owl:Class	
GO:0033793	biolink:NamedThing	aureusidin synthase activity	Catalysis of the reactions: 2',4,4',6'-tetrahydroxychalcone + O2 = aureusidin + H2O, and 2',3,4,4',6'-pentahydroxychalcone + 1/2 O2 = aureusidin + H2O.	tmpzr1t_l9r_go_relaxed.owl	2',4,4',6'-tetrahydroxychalcone:oxygen oxidoreductase activity													molecular_function											owl:Class	
GO:0080112	biolink:NamedThing	seed growth	The increase in size or mass of a seed. A seed is a propagating organ formed in the reproductive cycle of a spermatophyte, derived from the ovule and enclosing an embryo.	tmpzr1t_l9r_go_relaxed.owl								dhl	2009-04-27T02:52:07Z					biological_process											owl:Class	
GO:1903883	biolink:NamedThing	positive regulation of interleukin-17-mediated signaling pathway	Any process that activates or increases the frequency, rate or extent of interleukin-17-mediated signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of IL-17-mediated signalling pathway|upregulation of IL-17-mediated signalling pathway|upregulation of interleukin-17-mediated signaling pathway|up-regulation of interleukin-17-mediated signalling pathway|up regulation of IL-17-mediated signalling pathway|up-regulation of IL-17-mediated signaling pathway|positive regulation of IL-17-mediated signalling pathway|up regulation of interleukin-17-mediated signalling pathway|activation of IL-17-mediated signalling pathway|activation of IL-17-mediated signaling pathway|upregulation of interleukin-17-mediated signalling pathway|up regulation of IL-17-mediated signaling pathway|upregulation of IL-17-mediated signaling pathway|positive regulation of IL-17-mediated signaling pathway|activation of interleukin-17-mediated signaling pathway|positive regulation of interleukin-17-mediated signalling pathway|up regulation of interleukin-17-mediated signaling pathway|activation of interleukin-17-mediated signalling pathway|up-regulation of interleukin-17-mediated signaling pathway							krc	2015-02-06T16:26:56Z					biological_process											owl:Class	
GO:0008926	biolink:NamedThing	mannitol-1-phosphate 5-dehydrogenase activity	Catalysis of the reaction: D-mannitol 1-phosphate + NAD+ = D-fructose 6-phosphate + NADH + H+.	tmpzr1t_l9r_go_relaxed.owl					EC:1.1.1.17|MetaCyc:MANNPDEHYDROG-RXN|RHEA:19661									molecular_function											owl:Class	
GO:0017105	biolink:NamedThing	acyl-CoA delta11-desaturase activity	Catalysis of the reaction: acyl-CoA + reduced acceptor + O2 = delta11-acyl-CoA + acceptor + 2 H2O. The enzyme introduces a cis double bond at position C-11 of saturated fatty acyl-CoAs.	tmpzr1t_l9r_go_relaxed.owl	acyl-CoA delta(11)-desaturase activity|acyl-CoA D11-desaturase activity				EC:1.14.19.5									molecular_function											owl:Class	
GO:0060645	biolink:NamedThing	peripheral mammary gland bud epithelial cell differentiation	The process in which a relatively unspecialized epithelial cell of the mammary placode becomes an epithelial cell at the periphery of the mammary gland bud. Cells at the periphery of the bud are larger that those of the surrounding epithelium and are arranged concentrically.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-05-29T08:06:16Z					biological_process											owl:Class	
GO:0086050	biolink:NamedThing	membrane repolarization during bundle of His cell action potential	The process in which ions are transported across a membrane such that the bundle of His cardiac muscle cell membrane potential changes in the direction from the positive membrane potential at the peak of the action potential towards the negative resting potential.	tmpzr1t_l9r_go_relaxed.owl	membrane repolarization during bundle of His cardiac muscle cell action potential							dph	2011-11-16T11:50:41Z					biological_process											owl:Class	
GO:0009854	biolink:NamedThing	oxidative photosynthetic carbon pathway	The reactions of the C2 pathway bring about the metabolic conversion of two molecules of 2-phosphoglycolate to one molecule of 3-phosphoglycerate, which can be used by the C3 cycle, and one molecule of carbon dioxide (CO2).	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0052772	biolink:NamedThing	brefeldin A esterase activity	Catalysis of the hydrolysis of brefeldin A to produce brefeldin A acid. Brefeldin A is also known as gamma,4-dihydroxy-2-(6-hydroxy-1-heptenyl)-4-cyclopentanecrotonic acid lambda-lactone.	tmpzr1t_l9r_go_relaxed.owl	BFA esterase activity|brefeldin A hydrolase activity							ai	2011-10-03T12:01:00Z					molecular_function											owl:Class	
GO:0099121	biolink:NamedThing	fungal sorus development	The process whose specific outcome is the progression of a fungal sorus over time, from its formation to the mature structure. A fungal sorus is a spore containing structure.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0018277	biolink:NamedThing	protein deamination	The removal of an amino group from a protein amino acid.	tmpzr1t_l9r_go_relaxed.owl	protein amino acid deamination													biological_process											owl:Class	
GO:0102211	biolink:NamedThing	unsaturated rhamnogalacturonyl hydrolase activity	Catalysis of the reaction: 2-O-(4-deoxy-beta-L-threo-hex-4-enopyranuronosyl)-alpha-L-rhamnopyranose(1-) + H2O <=> (4S,5S)-4,5-dihydroxy-2,6-dioxohexanoate + alpha-L-rhamnopyranose.	tmpzr1t_l9r_go_relaxed.owl					RHEA:30927|EC:3.2.1.172|MetaCyc:RXN-12174									molecular_function											owl:Class	
GO:1905899	biolink:NamedThing	regulation of smooth muscle tissue development	Any process that modulates the frequency, rate or extent of smooth muscle tissue development.	tmpzr1t_l9r_go_relaxed.owl								bhm	2017-02-01T14:31:16Z					biological_process											owl:Class	
GO:0070191	biolink:NamedThing	methionine-R-sulfoxide reductase activity	Catalysis of the reaction: L-methionine R-oxide + thioredoxin = L-methionine + thioredoxin disulfide; can act on free oxidized methionine with specificity for the R enantiomer; does not act on oxidized methionine in peptide linkage. Thioredoxin disulfide is the oxidized form of thioredoxin.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0010654	biolink:NamedThing	apical cell fate commitment	The process in which the developmental fate of a cell becomes restricted such that it will develop into an apical cell. The apical cell is the upper cell formed after the first division of the zygote.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0003216	biolink:NamedThing	cardiac left atrium formation	The developmental process pertaining to the initial formation of a left cardiac atrium from unspecified parts.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-10-13T09:52:31Z					biological_process											owl:Class	
GO:0032430	biolink:NamedThing	positive regulation of phospholipase A2 activity	Any process that activates or increases the activity of the enzyme phospholipase A2.	tmpzr1t_l9r_go_relaxed.owl	stimulation of phospholipase A2 activity|up regulation of phospholipase A2 activity|up-regulation of phospholipase A2 activity|activation of phospholipase A2 activity|upregulation of phospholipase A2 activity													biological_process											owl:Class	
GO:1900116	biolink:NamedThing	extracellular negative regulation of signal transduction	Any negative regulation of signal transduction that takes place in extracellular region.	tmpzr1t_l9r_go_relaxed.owl	inhibition of signal transduction in extracellular region|downregulation of signal transduction in extracellular region|down-regulation of signal transduction in extracellular region|extracellular inhibition of signaling pathway|negative regulation of signaling pathway in extracellular region|down regulation of signal transduction in extracellular region|negative regulation of signalling pathway in extracellular region							bf	2012-02-22T10:27:56Z					biological_process											owl:Class	
GO:0016594	biolink:NamedThing	glycine binding	Binding to glycine, aminoethanoic acid.	tmpzr1t_l9r_go_relaxed.owl	aminoethanoic acid binding|aminoacetic acid binding|Gly binding													molecular_function											owl:Class	
GO:0110126	biolink:NamedThing	phloem loading	The process of loading solutes into the sieve tube or companion cell of the phloem for long distance transport from source to sink.	tmpzr1t_l9r_go_relaxed.owl								kmv	2018-09-07T21:24:54Z					biological_process											owl:Class	
GO:0005332	biolink:NamedThing	gamma-aminobutyric acid:sodium symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: gamma-aminobutyric acid(out) + Na+(out) = gamma-aminobutyric acid(in) + Na+(in).	tmpzr1t_l9r_go_relaxed.owl	4-aminobutyrate:sodium symporter activity|GABA:sodium symporter activity|sodium/chloride-dependent GABA transporter activity|betaine/GABA:sodium symporter activity|4-aminobutanoate:sodium symporter activity				Reactome:R-HSA-444007	See also the molecular function term 'neurotransmitter:sodium symporter activity ; GO:0005328'.								molecular_function											owl:Class	
GO:1902734	biolink:NamedThing	regulation of receptor-mediated virion attachment to host cell	Any process that modulates the frequency, rate or extent of receptor-mediated virion attachment to host cell.	tmpzr1t_l9r_go_relaxed.owl	regulation of virion attachment, binding of host cell surface receptor							als	2014-02-25T12:25:56Z					biological_process											owl:Class	
GO:0047115	biolink:NamedThing	trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity	Catalysis of the reaction: NADP+ + trans-1,2-dihydrobenzene-1,2-diol = NADPH + catechol.	tmpzr1t_l9r_go_relaxed.owl	dihydrodiol dehydrogenase activity|trans-1,2-dihydrobenzene-1,2-diol:NADP+ oxidoreductase activity				RHEA:16729|MetaCyc:1.3.1.20-RXN|EC:1.3.1.20									molecular_function											owl:Class	
GO:0103100	biolink:NamedThing	UDP-glucose: 6-methylthiohexylhydroximate S-glucosyltransferase activity	Catalysis of the reaction: UDP-alpha-D-glucose + 6-methylthiohexylhydroximate <=> H+ + 5-methylthiopentyldesulfoglucosinolate + UDP(3-).	tmpzr1t_l9r_go_relaxed.owl					EC:2.4.1.195|MetaCyc:RXNQT-4325									molecular_function											owl:Class	
GO:0004910	biolink:NamedThing	interleukin-1, type II, blocking receptor activity	Combining with interleukin-1 to initiate a change in cell activity by inhibiting the activity of type I interleukin receptors.	tmpzr1t_l9r_go_relaxed.owl	IL-1 type II, blocking binding|IL-1 type II, blocking receptor|interleukin-1, type II, blocking binding|interleukin-1 blocking receptor activity|interleukin-1 type II receptor activity											GO:0019968		molecular_function											owl:Class	
GO:0033291	biolink:NamedThing	eukaryotic 80S initiation complex	A protein complex composed of the large and small ribosomal subunits, methionyl-initiatior tRNA, and the capped mRNA. The initiator tRNA is positioned at the ribosomal P site at the AUG codon corresponding to the beginning of the coding region.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0019235	biolink:NamedThing	sensory perception of slow pain	The series of events required for an organism to receive a slow pain stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process. Slow pain is often subjectively described as an aching or throbbing pain; in humans, the signals from a slow pain stimulus are perceived and relayed along unmyelinated C fibers to the central nervous system, reaching their target in about 1 second. Slow pain is often associated with tissue destruction.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1990983	biolink:NamedThing	tRNA demethylation	The removal of a methyl group from one or more residues within a tRNA molecule.	tmpzr1t_l9r_go_relaxed.owl								sp	2016-10-28T08:32:59Z					biological_process											owl:Class	
GO:0043812	biolink:NamedThing	phosphatidylinositol-4-phosphate phosphatase activity	Catalysis of the reaction: phosphatidylinositol-4-phosphate + H2O = phosphatidylinositol + orthophosphate.	tmpzr1t_l9r_go_relaxed.owl	phosphatidylinositol 4-phosphate phosphatase activity													molecular_function											owl:Class	
GO:0075198	biolink:NamedThing	modulation of symbiont haustorium neck formation for entry into host	Any process that modulates the frequency, rate or extent of symbiont haustorium neck formation for entry into host. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl						Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products from the symbiont involved in this process.								biological_process											owl:Class	
GO:0019817	biolink:NamedThing	vesicle fusion with peroxisome	The joining of the lipid bilayer membrane around a vesicle with the lipid bilayer membrane around the peroxisome.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0008467	biolink:NamedThing	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity	Catalysis of the reaction: 3'-phosphoadenylyl sulfate + [heparan sulfate]-glucosamine = adenosine 3',5'-bisphosphate + [heparan sulfate]-glucosamine 3-sulfate. The [heparan sulfate]-glucosamine 3-sulfate has a substrate consensus sequence of Glc(N2S>NAc)+/-6S GlcA GlcN2S*+/-6S GlcA>IdoA+/-2S Glc(N2S/NAc)+/-6S.	tmpzr1t_l9r_go_relaxed.owl	heparin-glucosamine 3-O-sulphotransferase activity|3-OST-1 activity|3'-phosphoadenylyl-sulfate:[heparan sulfate]-glucosamine 3-sulfotransferase|glucosaminyl 3-O-sulfotransferase activity|heparan sulfate D-glucosaminyl 3-O-sulfotransferase activity|heparin-glucosamine 3-O-sulfotransferase activity|3'-phosphoadenylyl-sulfate:heparin-glucosamine 3-O-sulfotransferase activity|isoform/isozyme 1 (3-OST-1, HS3ST1)				EC:2.8.2.23|Reactome:R-HSA-2076611|MetaCyc:2.8.2.23-RXN|Reactome:R-HSA-2076383									molecular_function											owl:Class	
GO:1904276	biolink:NamedThing	regulation of wax biosynthetic process	Any process that modulates the frequency, rate or extent of wax biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of wax formation|regulation of wax biosynthesis|regulation of wax anabolism|regulation of wax synthesis							tb	2015-06-03T17:20:06Z					biological_process											owl:Class	
GO:0018220	biolink:NamedThing	peptidyl-threonine palmitoylation	The covalent attachment of a palmitoyl group to an oxygen (O) atom in a threonine residue to form peptidyl-O-palmitoyl-L-threonine.	tmpzr1t_l9r_go_relaxed.owl	peptidyl-threonine O-palmitoylation				RESID:AA0079	Palmitoylation of a non-terminal threonine residue always occurs on an oxygen (O) atom.								biological_process											owl:Class	
GO:0051073	biolink:NamedThing	adenosylcobinamide-GDP ribazoletransferase activity	Catalysis of the reaction: adenosylcobinamide-GDP + alpha-ribazole = GMP + adenosylcobalamin.	tmpzr1t_l9r_go_relaxed.owl	cobalamin (5'-phosphate) synthase activity|adenosylcobinamide-GDP:alpha-ribazole ribazoletransferase activity|cobalamin synthase activity|CobS|cobalamin-5'-phosphate synthase activity				MetaCyc:COBALAMINSYN-RXN|EC:2.7.8.26|RHEA:16049									molecular_function											owl:Class	
GO:0090324	biolink:NamedThing	negative regulation of oxidative phosphorylation	Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the phosphorylation of ADP to ATP that accompanies the oxidation of a metabolite through the operation of the respiratory chain. Oxidation of compounds establishes a proton gradient across the membrane, providing the energy for ATP synthesis.	tmpzr1t_l9r_go_relaxed.owl								tb	2010-05-14T10:21:33Z					biological_process											owl:Class	
GO:1903284	biolink:NamedThing	positive regulation of glutathione peroxidase activity	Any process that activates or increases the frequency, rate or extent of glutathione peroxidase activity.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of glutathione:hydrogen-peroxide oxidoreductase activity|positive regulation of reduced glutathione peroxidase activity|activation of glutathione peroxidase activity|up regulation of non-selenium glutathione peroxidase activity|up-regulation of glutathione peroxidase activity|up regulation of reduced glutathione peroxidase activity|upregulation of non-selenium glutathione peroxidase activity|upregulation of glutathione peroxidase activity|up regulation of glutathione peroxidase activity|up-regulation of selenium-glutathione peroxidase activity|activation of glutathione:hydrogen-peroxide oxidoreductase activity|activation of non-selenium glutathione peroxidase activity|positive regulation of non-selenium glutathione peroxidase activity|positive regulation of GSH peroxidase activity|activation of reduced glutathione peroxidase activity|up-regulation of GSH peroxidase activity|upregulation of GSH peroxidase activity|activation of selenium-glutathione peroxidase activity|activation of GSH peroxidase activity|up regulation of selenium-glutathione peroxidase activity|positive regulation of selenium-glutathione peroxidase activity|up-regulation of glutathione:hydrogen-peroxide oxidoreductase activity|up-regulation of non-selenium glutathione peroxidase activity|up regulation of GSH peroxidase activity|upregulation of glutathione:hydrogen-peroxide oxidoreductase activity|enhancement of GPX activity|upregulation of reduced glutathione peroxidase activity|up regulation of glutathione:hydrogen-peroxide oxidoreductase activity|up-regulation of reduced glutathione peroxidase activity|upregulation of selenium-glutathione peroxidase activity							bf	2014-08-11T13:14:30Z					biological_process											owl:Class	
GO:0000815	biolink:NamedThing	ESCRT III complex	A complex with membrane scission activity that plays a major role in many processes where membranes are remodelled - including endosomal transport (vesicle budding), nuclear envelope organisation (membrane closure, mitotic bridge cleavage), and cytokinesis (abscission).	tmpzr1t_l9r_go_relaxed.owl	endosomal sorting complex required for transport	https://github.com/geneontology/go-ontology/issues/22085												cellular_component											owl:Class	
GO:0030882	biolink:NamedThing	lipid antigen binding	Binding to a lipid antigen.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0099155	biolink:NamedThing	synaptic transmission, noradrenergic	The vesicular release of noradrenaline (norepinephrine) a presynapse, across a chemical synapse, the subsequent activation of noradrenaline receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse.	tmpzr1t_l9r_go_relaxed.owl	noradrenergic synaptic transmission							dos	2017-07-05T14:36:55Z					biological_process											owl:Class	
GO:0018010	biolink:NamedThing	glycoprotein N-palmitoyltransferase activity	Catalysis of the reaction: palmitoyl-CoA + glycoprotein = CoA + N-palmitoylglycoprotein.	tmpzr1t_l9r_go_relaxed.owl	palmitoyl-CoA:glycoprotein N-palmitoyltransferase activity|mucus glycoprotein fatty acyltransferase				MetaCyc:GLYCOPROTEIN-N-PALMITOYLTRANSFERASE-RXN									molecular_function											owl:Class	
GO:0043032	biolink:NamedThing	positive regulation of macrophage activation	Any process that stimulates, induces or increases the rate of macrophage activation.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of macrophage activation|up regulation of macrophage activation|stimulation of macrophage activation|activation of macrophage activation|upregulation of macrophage activation|positive regulation of macrophage polarization													biological_process											owl:Class	
GO:0043637	biolink:NamedThing	puromycin metabolic process	The chemical reactions and pathways involving puromycin, 3'-deoxy-N,N-dimethyl-3'-(O-methyl-L-tyrosinamido)adenosine, an aminonucleoside antibiotic that is a potent inhibitor of translation; produced by the bacterium Streptomyces alboniger.	tmpzr1t_l9r_go_relaxed.owl	puromycin metabolism													biological_process											owl:Class	
GO:1902231	biolink:NamedThing	positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage	Any process that activates or increases the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to DNA damage.	tmpzr1t_l9r_go_relaxed.owl	upregulation of intrinsic apoptotic signaling pathway in response to DNA damage|upregulation of DNA damage response, signal transduction resulting in induction of apoptosis|positive regulation of DNA damage response, signal transduction resulting in induction of apoptosis|up regulation of DNA damage response, signal transduction resulting in induction of apoptosis|activation of DNA damage response, signal transduction resulting in induction of apoptosis|up regulation of intrinsic apoptotic signaling pathway in response to DNA damage|up-regulation of intrinsic apoptotic signaling pathway in response to DNA damage|activation of intrinsic apoptotic signaling pathway in response to DNA damage|up-regulation of DNA damage response, signal transduction resulting in induction of apoptosis							rl	2013-06-14T09:40:03Z					biological_process											owl:Class	
GO:0010303	biolink:NamedThing	limit dextrinase activity	Catalysis of the hydrolysis of (1,6)-alpha-D-glucosidic linkages in alpha- and beta-limit dextrins of amylopectin and glycogen, and in amylopectin and pullulan.	tmpzr1t_l9r_go_relaxed.owl	R-enzyme|dextrin alpha-1,6-glucanohydrolase activity|amylopectin-1,6-glucosidase activity				MetaCyc:3.2.1.142-RXN|MetaCyc:3.2.1.10-RXN|EC:3.2.1.142|MetaCyc:RXN-1824									molecular_function											owl:Class	
GO:0038028	biolink:NamedThing	insulin receptor signaling pathway via phosphatidylinositol 3-kinase	The series of molecular signals generated as a consequence of the insulin receptor binding to its physiological ligand, where the signal is passed on via the phosphatidylinositol 3-kinase cascade.	tmpzr1t_l9r_go_relaxed.owl	insulin receptor signaling pathway via phosphatidylinositol 3-kinase cascade|insulin receptor signaling via PI3K|insulin receptor signaling pathway via PI3K cascade|insulin receptor signalling pathway via phosphatidylinositol 3-kinase cascade							bf	2011-09-08T10:35:14Z					biological_process											owl:Class	
GO:1904992	biolink:NamedThing	positive regulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway	Any process that activates or increases the frequency, rate or extent of adenylate cyclase-inhibiting dopamine receptor signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of dopamine receptor, adenylyl cyclase inhibiting pathway|upregulation of inhibition of adenylate cyclase activity by dopamine receptor signalling pathway|positive regulation of inhibition of adenylate cyclase activity by dopamine receptor signaling pathway|up regulation of dopamine receptor, adenylyl cyclase inhibiting pathway|up regulation of dopamine receptor, adenylate cyclase inhibiting pathway|activation of dopamine receptor, adenylate cyclase inhibiting pathway|up regulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway|upregulation of dopamine receptor, adenylyl cyclase inhibiting pathway|positive regulation of dopamine receptor, adenylyl cyclase inhibiting pathway|upregulation of dopamine receptor, adenylate cyclase inhibiting pathway|up regulation of inhibition of adenylate cyclase activity by dopamine receptor signalling pathway|upregulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway|activation of inhibition of adenylate cyclase activity by dopamine receptor signalling pathway|positive regulation of inhibition of adenylate cyclase activity by dopamine receptor signalling pathway|positive regulation of dopamine receptor, adenylate cyclase inhibiting pathway|activation of adenylate cyclase-inhibiting dopamine receptor signaling pathway|activation of dopamine receptor, adenylyl cyclase inhibiting pathway|up-regulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway|upregulation of inhibition of adenylate cyclase activity by dopamine receptor signaling pathway|up-regulation of inhibition of adenylate cyclase activity by dopamine receptor signalling pathway|activation of inhibition of adenylate cyclase activity by dopamine receptor signaling pathway|up regulation of inhibition of adenylate cyclase activity by dopamine receptor signaling pathway|up-regulation of inhibition of adenylate cyclase activity by dopamine receptor signaling pathway|up-regulation of dopamine receptor, adenylate cyclase inhibiting pathway							kmv	2016-02-29T22:42:33Z					biological_process											owl:Class	
GO:0001856	biolink:NamedThing	complement component C5a binding	Binding to a C5a product of the complement cascade.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0047398	biolink:NamedThing	dolichylphosphate-mannose phosphodiesterase activity	Catalysis of the reaction: dolichyl beta-D-mannosyl phosphate + H2O = dolichol-phosphate + mannose.	tmpzr1t_l9r_go_relaxed.owl	mannosylphosphodolichol phosphodiesterase activity|dolichyl-beta-D-mannosyl-phosphate dolichylphosphohydrolase activity				MetaCyc:3.1.4.49-RXN|RHEA:12989|EC:3.1.4.49									molecular_function											owl:Class	
GO:0032068	biolink:NamedThing	type IV site-specific deoxyribonuclease complex	A complex consisting of two proteins which acts as an endonuclease in DNA sequences containing a specific modified recognition site. Modifications may include methylation, hydroxymethylation, and glucosyl-hydroxymethylation.	tmpzr1t_l9r_go_relaxed.owl	type IV restriction enzyme complex													cellular_component											owl:Class	
GO:0034241	biolink:NamedThing	positive regulation of macrophage fusion	Any process that activates or increases the frequency, rate or extent of macrophage fusion.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0050346	biolink:NamedThing	trans-L-3-hydroxyproline dehydratase activity	Catalysis of the reaction: trans-L-3-hydroxyproline = 1-pyrroline-2-carboxylate + H(2)O + H(+).	tmpzr1t_l9r_go_relaxed.owl	trans-L-3-hydroxyproline hydro-lyase activity|trans-L-3-hydroxyproline hydro-lyase (Delta1-pyrroline 2-carboxylate-forming)				EC:4.2.1.77|KEGG_REACTION:R04374|MetaCyc:TRANS-L-3-HYDROXYPROLINE-DEHYDRATASE-RXN|RHEA:10320									molecular_function											owl:Class	
GO:0000340	biolink:NamedThing	RNA 7-methylguanosine cap binding	Binding to a 7-methylguanosine group added cotranscriptionally to the 5' end of RNA molecules transcribed by polymerase II.	tmpzr1t_l9r_go_relaxed.owl	RNA m7G cap binding													molecular_function											owl:Class	
GO:0000339	biolink:NamedThing	RNA cap binding	Binding to a 7-methylguanosine (m7G) group or derivative located at the 5' end of an RNA molecule.	tmpzr1t_l9r_go_relaxed.owl	snRNA cap binding|binding to mRNA cap|mRNA cap binding													molecular_function											owl:Class	
GO:0016886	biolink:NamedThing	ligase activity, forming phosphoric ester bonds	Catalysis of the joining of two molecules, or two groups within a single molecule, via a phosphoric ester bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.	tmpzr1t_l9r_go_relaxed.owl					EC:6.5.-.-									molecular_function											owl:Class	
GO:0031606	biolink:NamedThing	cytosolic proteasome core complex, alpha-subunit complex	The proteasome core subcomplex that constitutes the two outer rings of the cytosolic proteasome core complex.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0019773	biolink:NamedThing	proteasome core complex, alpha-subunit complex	The proteasome core subcomplex that constitutes the two outer rings of the proteasome core complex. An example of this component is found in Mus musculus.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0072214	biolink:NamedThing	metanephric cortex development	The process whose specific outcome is the progression of the metanephric cortex over time, from its formation to the mature structure. The metanephric cortex is the outer region of the metanephros.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-03-18T01:29:49Z					biological_process											owl:Class	
GO:0098021	biolink:NamedThing	viral capsid, decoration	Component of the virus capsid (head), located on the outer head surface. Involved in the stabilization of the head structure and usually non-essential.	tmpzr1t_l9r_go_relaxed.owl	decoration protein							bm	2012-07-19T11:52:53Z					cellular_component											owl:Class	
GO:0003159	biolink:NamedThing	morphogenesis of an endothelium	The process in which the anatomical structure of an endothelium is generated and organized. Endothelium refers to the layer of cells lining blood vessels, lymphatics, the heart, and serous cavities, and is derived from bone marrow or mesoderm. Corneal endothelium is a special case, derived from neural crest cells.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-10-01T01:34:06Z					biological_process											owl:Class	
GO:0022628	biolink:NamedThing	chloroplast large ribosomal subunit	The large subunit of a ribosome contained within a chloroplast.	tmpzr1t_l9r_go_relaxed.owl	chloroplast ribosomal LSU complex|chloroplast ribosomal large subunit complex													cellular_component											owl:Class	
GO:0004531	biolink:NamedThing	deoxyribonuclease II activity	Catalysis of the endonucleolytic cleavage of DNA to 3'-phosphodinucleotide and 3'-phosphooligonucleotide end products.	tmpzr1t_l9r_go_relaxed.owl	DNase II activity|lysosomal DNase II activity|acid deoxyribonuclease activity|acid DNase activity|pancreatic DNase II|deoxyribonucleate 3'-nucleotidohydrolase activity				EC:3.1.22.1|MetaCyc:3.1.22.1-RXN									molecular_function											owl:Class	
GO:2000210	biolink:NamedThing	positive regulation of anoikis	Any process that activates or increases the frequency, rate or extent of anoikis.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of suspension induced apoptosis|positive regulation of detachment induced cell death							mah	2010-11-03T02:00:36Z					biological_process											owl:Class	
GO:0072499	biolink:NamedThing	photoreceptor cell axon guidance	The chemotaxis process that directs the migration of a photoreceptor cell axon growth cone to its target in the optic lobe in response to a combination of attractive and repulsive cues.	tmpzr1t_l9r_go_relaxed.owl	photoreceptor cell axon pathfinding							mah	2010-12-15T05:34:10Z					biological_process											owl:Class	
GO:0085001	biolink:NamedThing	formation of stylet for nutrient acquisition	The assembly of a stylet, a hollow protrusible spear-like symbiont structure projected into the host cell for the purpose of obtaining nutrients. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	formation by symbiont of stylet for nutrient acquisition from host	https://github.com/geneontology/go-ontology/issues/20305						jl	2010-02-24T01:49:06Z					biological_process											owl:Class	
GO:0032337	biolink:NamedThing	positive regulation of activin secretion	Any process that activates or increases the frequency, rate or extent of the regulated release of activin from a cell.	tmpzr1t_l9r_go_relaxed.owl	stimulation of activin secretion|activation of activin secretion|up-regulation of activin secretion|up regulation of activin secretion|upregulation of activin secretion													biological_process											owl:Class	
GO:0048074	biolink:NamedThing	negative regulation of eye pigmentation	Any process that stops, prevents, or reduces the frequency, rate or extent of establishment of a pattern of pigment in the eye of an organism.	tmpzr1t_l9r_go_relaxed.owl	downregulation of eye pigmentation|down regulation of eye pigmentation|down-regulation of eye pigmentation|inhibition of eye pigmentation													biological_process											owl:Class	
GO:0046347	biolink:NamedThing	mannosamine biosynthetic process	The chemical reactions and pathways resulting in the formation of mannosomine, 2-amino-2-deoxymannose; the D-isomer is a constituent of neuraminic acids as well as mucolipids and mucoproteins.	tmpzr1t_l9r_go_relaxed.owl	mannosamine formation|mannosamine synthesis|mannosamine biosynthesis|mannosamine anabolism													biological_process											owl:Class	
GO:0033329	biolink:NamedThing	kaempferol O-glucoside metabolic process	The chemical reactions and pathways involving O-glucosylated derivatives of kaempferol.	tmpzr1t_l9r_go_relaxed.owl	kaempferol O-glucoside metabolism													biological_process											owl:Class	
GO:0030340	biolink:NamedThing	hyaluronate lyase activity	Catalysis of the reaction: hyaluronate = n 3-(4-deoxy-beta-D-gluc-4-enuronosyl)-N-acetyl-D-glucosamine.	tmpzr1t_l9r_go_relaxed.owl	hyaluronidase activity|mucinase activity|hyaluronidase [but cf. EC:3.2.1.35 (hyalurononglucosaminidase) and EC:3.2.1.36 (hyaluronoglucuronidase)]|glucuronoglycosaminoglycan lyase activity|spreading factor activity				EC:4.2.2.1|MetaCyc:HYALURONATE-LYASE-RXN|RHEA:50240									molecular_function											owl:Class	
GO:0033446	biolink:NamedThing	AGC codon-amino acid adaptor activity	A triplet codon-amino acid adaptor activity that recognizes an AGC codon.	tmpzr1t_l9r_go_relaxed.owl	serine tRNA					Note that in the standard genetic code, AGC codes for serine.								molecular_function											owl:Class	
GO:0071743	biolink:NamedThing	IgE immunoglobulin complex, circulating	A protein complex composed of two identical immunoglobulin heavy chains of the IgE isotype and two identical immunoglobulin light chains, held together by disulfide bonds, and present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.	tmpzr1t_l9r_go_relaxed.owl	IgE antibody					Note that an IgE immunoglobulin complex has the function of antigen binding if a suitable antigen is available.		mah	2010-03-24T01:44:53Z					cellular_component											owl:Class	
GO:1904692	biolink:NamedThing	positive regulation of type B pancreatic cell proliferation	Any process that activates or increases the frequency, rate or extent of type B pancreatic cell proliferation.	tmpzr1t_l9r_go_relaxed.owl	up regulation of pancreatic beta cell proliferation|upregulation of pancreatic beta cell proliferation|up-regulation of type B pancreatic cell proliferation|up-regulation of pancreatic beta cell proliferation|activation of pancreatic B cell proliferation|up-regulation of pancreatic B cell proliferation|positive regulation of pancreatic beta cell proliferation|activation of type B pancreatic cell proliferation|upregulation of type B pancreatic cell proliferation|upregulation of pancreatic B cell proliferation|activation of pancreatic beta cell proliferation|positive regulation of pancreatic B cell proliferation|up regulation of type B pancreatic cell proliferation|up regulation of pancreatic B cell proliferation							sl	2015-09-25T15:23:44Z					biological_process											owl:Class	
GO:0009916	biolink:NamedThing	alternative oxidase activity	Catalysis of the oxidation of ubiquinol by diverting electrons from the standard electron transfer chain, transferring them from ubiquinol to oxygen and generating water as the product.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0047981	biolink:NamedThing	histidine N-acetyltransferase activity	Catalysis of the reaction: L-histidine + acetyl-CoA = N(alpha)-acetyl-L-histidine + CoA + H(+).	tmpzr1t_l9r_go_relaxed.owl	histidine acetyltransferase activity|acetylhistidine synthetase activity|acetyl-CoA:L-histidine N-acetyltransferase activity				EC:2.3.1.33|KEGG_REACTION:R01160|MetaCyc:HISTIDINE-N-ACETYLTRANSFERASE-RXN|RHEA:24596									molecular_function											owl:Class	
GO:0097604	biolink:NamedThing	temperature-gated cation channel activity	Enables the transmembrane transfer of a cation by a channel that opens in response to a temperature stimulus (e.g. exposure to a temperature range different than the optimal temperature for that organism).	tmpzr1t_l9r_go_relaxed.owl	temperature gated cation channel activity|heat-activated cation channel activity|temperature-dependent cation channel activity|temperature-activated cation channel activity							pr	2014-05-12T13:13:46Z					molecular_function											owl:Class	
GO:0050386	biolink:NamedThing	ureidosuccinase activity	Catalysis of the reaction: N-carbamoyl-L-aspartate + H(2)O + 2 H(+) = L-aspartate + CO(2) + NH(4)(+).	tmpzr1t_l9r_go_relaxed.owl	N-carbamoyl-L-aspartate amidohydrolase activity				RHEA:14365|MetaCyc:UREIDOSUCCINASE-RXN|KEGG_REACTION:R00484|EC:3.5.1.7									molecular_function											owl:Class	
GO:0047027	biolink:NamedThing	benzyl-2-methyl-hydroxybutyrate dehydrogenase activity	Catalysis of the reaction: benzyl (2R,3S)-2-methyl-3-hydroxybutanoate + NADP(+) = benzyl 2-methyl-3-oxobutanoate + H(+) + NADPH.	tmpzr1t_l9r_go_relaxed.owl	benzyl-(2R,3S)-2-methyl-3-hydroxybutanoate:NADP+ 3-oxidoreductase activity|benzyl 2-methyl-3-hydroxybutyrate dehydrogenase activity				EC:1.1.1.217|RHEA:16405|KEGG_REACTION:R04370|MetaCyc:1.1.1.217-RXN									molecular_function											owl:Class	
GO:0047543	biolink:NamedThing	2-hexadecenal reductase activity	Catalysis of the reaction: NADP(+) + palmitaldehyde = trans-hexadec-2-enal + H(+) + NADPH.	tmpzr1t_l9r_go_relaxed.owl	hexadecanal: NADP+ oxidoreductase activity|hexadecanal:NADP+ delta2-oxidoreductase activity				MetaCyc:2-HEXADECENAL-REDUCTASE-RXN|RHEA:12444|EC:1.3.1.27|KEGG_REACTION:R02463									molecular_function											owl:Class	
GO:0010501	biolink:NamedThing	RNA secondary structure unwinding	The process in which a secondary structure of RNA are broken or 'melted'.	tmpzr1t_l9r_go_relaxed.owl	RNA duplex unwinding													biological_process											owl:Class	
GO:0075210	biolink:NamedThing	suppression by symbiont of host cAMP-mediated signal transduction	Any process in which the symbiont organism stops, prevents, or reduces the frequency, rate or extent of cAMP-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	negative regulation by symbiont of host cAMP-mediated signal transduction|negative regulation by symbiont of host cAMP-mediated signaling					Note that this term is used to annotate gene products of the symbiont. To annotate host gene products, consider the biological process term "Negative regulation by host of symbiont cAMP-mediated signal transduction ; GO:0075207".								biological_process											owl:Class	
GO:1905425	biolink:NamedThing	negative regulation of Wnt-mediated midbrain dopaminergic neuron differentiation	Any process that stops, prevents or reduces the frequency, rate or extent of Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation.	tmpzr1t_l9r_go_relaxed.owl	downregulation of Wnt signaling pathway involved in midbrain DA neurogenesis|down-regulation of Wnt receptor signalling pathway involved in midbrain DA neurogenesis|down regulation of Wg signaling pathway involved in DA neurogenesis from midbrain floor plate|negative regulation of Wnt signaling pathway involved in mDA neuron differentiation|down-regulation of Wingless signaling pathway involved in midbrain DA neurogenesis|negative regulation of frizzled signalling pathway involved in midbrain DA neurogenesis|downregulation of Wnt-activated signaling pathway involved in midbrain DA neurogenesis|down regulation of Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation|down-regulation of Wnt receptor signaling pathway involved in midbrain dopaminergic neuron differentiation|down regulation of Wnt receptor signalling pathway involved in mDA neuron differentiation|negative regulation of Wingless signaling pathway involved in DA neurogenesis from midbrain floor plate|inhibition of Wnt receptor signalling pathway involved in midbrain dopaminergic neuron differentiation|inhibition of Wingless signaling pathway involved in midbrain dopaminergic neuron production|down regulation of Wingless signalling pathway involved in midbrain dopaminergic neuron production|down regulation of Wingless signaling pathway involved in DA neurogenesis from midbrain floor plate|down-regulation of Wg signaling pathway involved in DA neurogenesis from midbrain floor plate|negative regulation of Wnt receptor signalling pathway involved in midbrain dopaminergic neuron differentiation|down regulation of Wnt receptor signaling pathway involved in DA neurogenesis from midbrain floor plate|downregulation of Wnt receptor signalling pathway involved in mDA neuron differentiation|downregulation of Wnt-activated signaling pathway involved in DA neurogenesis from midbrain floor plate|down-regulation of Wg signalling pathway involved in midbrain DA neurogenesis|inhibition of Wnt-activated signaling pathway involved in DA neurogenesis from midbrain floor plate|inhibition of Wnt-mediated midbrain DA neuron differentiation|down regulation of frizzled signaling pathway involved in midbrain dopaminergic neuron production|negative regulation of Wnt receptor signalling pathway involved in DA neurogenesis from midbrain floor plate|down-regulation of Wg signalling pathway involved in DA neurogenesis from midbrain floor plate|downregulation of frizzled signalling pathway involved in mDA neuron differentiation|inhibition of Wingless signaling pathway involved in midbrain DA neurogenesis|down regulation of Wg signaling pathway involved in mDA neuron differentiation|negative regulation of Wingless signalling pathway involved in mDA neuron differentiation|downregulation of frizzled signalling pathway involved in midbrain DA neurogenesis|negative regulation of Wg signaling pathway involved in mDA neuron differentiation|negative regulation of Wg signalling pathway involved in midbrain dopaminergic neuron differentiation|negative regulation of Wingless signaling pathway involved in midbrain DA neurogenesis|inhibition of frizzled signalling pathway involved in midbrain dopaminergic neuron production|down-regulation of frizzled signaling pathway involved in midbrain dopaminergic neuron production|downregulation of Wnt receptor signalling pathway involved in DA neurogenesis from midbrain floor plate|negative regulation of Wnt signaling pathway involved in midbrain dopaminergic neuron production|down-regulation of Wg signaling pathway involved in midbrain DA neurogenesis|inhibition of frizzled signaling pathway involved in mDA neuron differentiation|down regulation of Wnt receptor signaling pathway involved in midbrain DA neurogenesis|downregulation of Wnt-mediated midbrain DA neuron differentiation|inhibition of frizzled signaling pathway involved in DA neurogenesis from midbrain floor plate|inhibition of Wingless signaling pathway involved in midbrain dopaminergic neuron differentiation|downregulation of frizzled signalling pathway involved in midbrain dopaminergic neuron production|downregulation of Wingless signalling pathway involved in DA neurogenesis from midbrain floor plate|down-regulation of Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation|downregulation of Wg signaling pathway involved in mDA neuron differentiation|negative regulation of Wg signaling pathway involved in midbrain dopaminergic neuron differentiation|down regulation of Wnt-activated signaling pathway involved in midbrain dopaminergic neuron differentiation|down regulation of Wingless signaling pathway involved in midbrain dopaminergic neuron production|negative regulation of frizzled signaling pathway involved in DA neurogenesis from midbrain floor plate|down-regulation of Wnt signaling pathway involved in midbrain DA neurogenesis|downregulation of Wingless signaling pathway involved in mDA neuron differentiation|down regulation of Wingless signalling pathway involved in DA neurogenesis from midbrain floor plate|inhibition of Wingless signalling pathway involved in midbrain dopaminergic neuron differentiation|inhibition of Wnt receptor signaling pathway involved in DA neurogenesis from midbrain floor plate|downregulation of Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation|down-regulation of frizzled signaling pathway involved in midbrain dopaminergic neuron differentiation|inhibition of Wnt receptor signalling pathway involved in mDA neuron differentiation|down-regulation of Wnt-activated signaling pathway involved in midbrain dopaminergic neuron differentiation|down-regulation of Wnt signaling pathway involved in midbrain dopaminergic neuron production|inhibition of Wnt signaling pathway involved in midbrain DA neurogenesis|down-regulation of Wnt-activated signaling pathway involved in DA neurogenesis from midbrain floor plate|downregulation of Wnt receptor signaling pathway involved in mDA neuron differentiation|down-regulation of Wnt receptor signalling pathway involved in midbrain dopaminergic neuron production|negative regulation of Wnt receptor signalling pathway involved in midbrain DA neurogenesis|inhibition of Wingless signalling pathway involved in DA neurogenesis from midbrain floor plate|negative regulation of Wnt-mediated midbrain DA neuron differentiation|down-regulation of Wnt-mediated midbrain DA neuron differentiation|negative regulation of Wingless signalling pathway involved in DA neurogenesis from midbrain floor plate|negative regulation of Wingless signalling pathway involved in midbrain dopaminergic neuron production|negative regulation of midbrain dopaminergic neuron differentiation by negative regulation of Wnt signaling|down regulation of Wnt receptor signalling pathway involved in DA neurogenesis from midbrain floor plate|down regulation of Wingless signalling pathway involved in mDA neuron differentiation|down regulation of Wnt signaling pathway involved in midbrain dopaminergic neuron production|negative regulation of Wg signaling pathway involved in DA neurogenesis from midbrain floor plate|down regulation of Wg signalling pathway involved in DA neurogenesis from midbrain floor plate|inhibition of Wg signaling pathway involved in DA neurogenesis from midbrain floor plate|negative regulation of frizzled signaling pathway involved in mDA neuron differentiation|downregulation of Wg signalling pathway involved in midbrain dopaminergic neuron production|downregulation of Wg signaling pathway involved in DA neurogenesis from midbrain floor plate|negative regulation of Wg signalling pathway involved in midbrain DA neurogenesis|inhibition of Wnt signaling pathway involved in mDA neuron differentiation|inhibition of Wg signalling pathway involved in DA neurogenesis from midbrain floor plate|inhibition of frizzled signaling pathway involved in midbrain DA neurogenesis|down regulation of Wg signaling pathway involved in midbrain dopaminergic neuron production|down regulation of Wnt-activated signaling pathway involved in DA neurogenesis from midbrain floor plate|down-regulation of Wg signalling pathway involved in midbrain dopaminergic neuron production|down regulation of Wnt receptor signaling pathway involved in midbrain dopaminergic neuron production|inhibition of frizzled signalling pathway involved in mDA neuron differentiation|negative regulation of Wnt-activated signaling pathway involved in mDA neuron differentiation|inhibition of Wingless signaling pathway involved in mDA neuron differentiation|downregulation of Wingless signalling pathway involved in mDA neuron differentiation|down-regulation of frizzled signaling pathway involved in DA neurogenesis from midbrain floor plate|downregulation of frizzled signalling pathway involved in midbrain dopaminergic neuron differentiation|negative regulation of Wnt receptor signalling pathway involved in midbrain dopaminergic neuron production|down regulation of Wnt signaling pathway involved in midbrain DA neurogenesis|inhibition of Wingless signaling pathway involved in DA neurogenesis from midbrain floor plate|down-regulation of Wnt-activated signaling pathway involved in midbrain DA neurogenesis|negative regulation of Wnt receptor signaling pathway involved in midbrain DA neurogenesis|downregulation of Wnt receptor signaling pathway involved in midbrain dopaminergic neuron production|down-regulation of frizzled signaling pathway involved in mDA neuron differentiation|downregulation of frizzled signaling pathway involved in midbrain dopaminergic neuron differentiation|negative regulation of frizzled signaling pathway involved in midbrain dopaminergic neuron differentiation|down regulation of Wnt signaling pathway involved in DA neurogenesis from midbrain floor plate|inhibition of Wnt-activated signaling pathway involved in midbrain dopaminergic neuron production|inhibition of frizzled signalling pathway involved in midbrain dopaminergic neuron differentiation|inhibition of Wnt receptor signalling pathway involved in midbrain dopaminergic neuron production|down-regulation of Wnt-activated signaling pathway involved in midbrain dopaminergic neuron production|down-regulation of Wg signalling pathway involved in mDA neuron differentiation|inhibition of Wg signaling pathway involved in midbrain dopaminergic neuron differentiation|inhibition of Wingless signalling pathway involved in midbrain dopaminergic neuron production|down-regulation of Wingless signaling pathway involved in midbrain dopaminergic neuron differentiation|down regulation of frizzled signalling pathway involved in DA neurogenesis from midbrain floor plate|inhibition of Wingless signalling pathway involved in mDA neuron differentiation|downregulation of Wnt receptor signalling pathway involved in midbrain dopaminergic neuron production|negative regulation of Wg signalling pathway involved in midbrain dopaminergic neuron production|down regulation of Wnt-activated signaling pathway involved in midbrain dopaminergic neuron production|negative regulation of frizzled signalling pathway involved in DA neurogenesis from midbrain floor plate|inhibition of Wnt signaling pathway involved in midbrain dopaminergic neuron production|down-regulation of Wingless signaling pathway involved in mDA neuron differentiation|down-regulation of frizzled signalling pathway involved in midbrain DA neurogenesis|downregulation of Wingless signaling pathway involved in midbrain dopaminergic neuron production|negative regulation of Wingless signaling pathway involved in midbrain dopaminergic neuron production|down-regulation of Wg signaling pathway involved in midbrain dopaminergic neuron production|negative regulation of frizzled signalling pathway involved in midbrain dopaminergic neuron production|down-regulation of Wnt-activated signaling pathway involved in mDA neuron differentiation|downregulation of frizzled signalling pathway involved in DA neurogenesis from midbrain floor plate|down regulation of frizzled signaling pathway involved in midbrain dopaminergic neuron differentiation|down-regulation of Wingless signalling pathway involved in midbrain dopaminergic neuron production|down regulation of Wg signalling pathway involved in midbrain dopaminergic neuron differentiation|downregulation of Wnt-activated signaling pathway involved in mDA neuron differentiation|down-regulation of Wingless signaling pathway involved in DA neurogenesis from midbrain floor plate|downregulation of Wingless signaling pathway involved in DA neurogenesis from midbrain floor plate|downregulation of frizzled signaling pathway involved in mDA neuron differentiation|downregulation of Wnt receptor signalling pathway involved in midbrain dopaminergic neuron differentiation|downregulation of Wg signalling pathway involved in midbrain dopaminergic neuron differentiation|inhibition of Wg signalling pathway involved in midbrain DA neurogenesis|down regulation of Wingless signaling pathway involved in midbrain DA neurogenesis|down regulation of Wg signaling pathway involved in midbrain DA neurogenesis|down-regulation of Wingless signalling pathway involved in midbrain DA neurogenesis|down regulation of Wingless signalling pathway involved in midbrain dopaminergic neuron differentiation|down-regulation of Wnt receptor signaling pathway involved in DA neurogenesis from midbrain floor plate|down regulation of Wingless signaling pathway involved in mDA neuron differentiation|down regulation of Wnt-mediated midbrain DA neuron differentiation|downregulation of frizzled signaling pathway involved in midbrain DA neurogenesis|negative regulation of Wnt-activated signaling pathway involved in midbrain dopaminergic neuron production|downregulation of Wnt signaling pathway involved in midbrain dopaminergic neuron production|negative regulation of Wnt-activated signaling pathway involved in midbrain dopaminergic neuron differentiation|inhibition of frizzled signaling pathway involved in midbrain dopaminergic neuron production|negative regulation of Wingless signalling pathway involved in midbrain dopaminergic neuron differentiation|down-regulation of Wnt receptor signaling pathway involved in midbrain DA neurogenesis|inhibition of frizzled signalling pathway involved in DA neurogenesis from midbrain floor plate|down regulation of Wnt receptor signalling pathway involved in midbrain DA neurogenesis|downregulation of Wnt receptor signaling pathway involved in midbrain DA neurogenesis|down-regulation of Wg signaling pathway involved in mDA neuron differentiation|down regulation of Wnt receptor signalling pathway involved in midbrain dopaminergic neuron differentiation|down-regulation of Wg signalling pathway involved in midbrain dopaminergic neuron differentiation|down regulation of frizzled signalling pathway involved in midbrain dopaminergic neuron differentiation|downregulation of Wingless signaling pathway involved in midbrain DA neurogenesis|downregulation of Wnt signaling pathway involved in DA neurogenesis from midbrain floor plate|downregulation of Wingless signaling pathway involved in midbrain dopaminergic neuron differentiation|inhibition of frizzled signaling pathway involved in midbrain dopaminergic neuron differentiation|down-regulation of frizzled signalling pathway involved in midbrain dopaminergic neuron production|negative regulation of Wg signaling pathway involved in midbrain DA neurogenesis|downregulation of Wnt receptor signaling pathway involved in midbrain dopaminergic neuron differentiation|down regulation of frizzled signaling pathway involved in mDA neuron differentiation|negative regulation of Wg signalling pathway involved in mDA neuron differentiation|negative regulation of frizzled signaling pathway involved in midbrain DA neurogenesis|negative regulation of frizzled signalling pathway involved in mDA neuron differentiation|downregulation of Wnt signaling pathway involved in mDA neuron differentiation|down-regulation of Wnt signaling pathway involved in DA neurogenesis from midbrain floor plate|down-regulation of Wingless signaling pathway involved in midbrain dopaminergic neuron production|negative regulation of Wg signaling pathway involved in midbrain dopaminergic neuron production|inhibition of Wnt receptor signalling pathway involved in midbrain DA neurogenesis|negative regulation of Wnt receptor signaling pathway involved in midbrain dopaminergic neuron differentiation|negative regulation of Wingless signaling pathway involved in midbrain dopaminergic neuron differentiation|negative regulation of frizzled signaling pathway involved in midbrain dopaminergic neuron production|downregulation of Wg signalling pathway involved in midbrain DA neurogenesis|inhibition of Wg signalling pathway involved in midbrain dopaminergic neuron differentiation|down-regulation of Wnt receptor signalling pathway involved in mDA neuron differentiation|downregulation of Wingless signalling pathway involved in midbrain dopaminergic neuron differentiation|down-regulation of Wingless signalling pathway involved in DA neurogenesis from midbrain floor plate|down regulation of frizzled signalling pathway involved in mDA neuron differentiation|negative regulation of Wnt receptor signalling pathway involved in mDA neuron differentiation|inhibition of Wingless signalling pathway involved in midbrain DA neurogenesis|down-regulation of frizzled signalling pathway involved in DA neurogenesis from midbrain floor plate|inhibition of Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation|down regulation of Wnt signaling pathway involved in mDA neuron differentiation|down regulation of Wingless signaling pathway involved in midbrain dopaminergic neuron differentiation|negative regulation of Wnt-activated signaling pathway involved in DA neurogenesis from midbrain floor plate|down regulation of Wnt-activated signaling pathway involved in midbrain DA neurogenesis|negative regulation of Wnt signaling pathway involved in DA neurogenesis from midbrain floor plate|negative regulation of Wnt signaling pathway involved in midbrain DA neurogenesis|inhibition of Wnt-activated signaling pathway involved in mDA neuron differentiation|downregulation of Wg signalling pathway involved in mDA neuron differentiation|inhibition of Wnt receptor signaling pathway involved in midbrain dopaminergic neuron differentiation|negative regulation of Wnt-activated signaling pathway involved in midbrain DA neurogenesis|inhibition of Wg signaling pathway involved in midbrain dopaminergic neuron production|down-regulation of Wnt receptor signaling pathway involved in midbrain dopaminergic neuron production|negative regulation of Wnt receptor signaling pathway involved in DA neurogenesis from midbrain floor plate|downregulation of Wnt-activated signaling pathway involved in midbrain dopaminergic neuron production|down regulation of frizzled signaling pathway involved in DA neurogenesis from midbrain floor plate|down regulation of Wg signalling pathway involved in mDA neuron differentiation|down regulation of Wingless signalling pathway involved in midbrain DA neurogenesis|negative regulation of frizzled signalling pathway involved in midbrain dopaminergic neuron differentiation|inhibition of Wnt receptor signaling pathway involved in mDA neuron differentiation|down regulation of Wnt-activated signaling pathway involved in mDA neuron differentiation|down regulation of Wnt receptor signaling pathway involved in mDA neuron differentiation|down regulation of Wnt receptor signaling pathway involved in midbrain dopaminergic neuron differentiation|down regulation of frizzled signaling pathway involved in midbrain DA neurogenesis|negative regulation of Wingless signaling pathway involved in mDA neuron differentiation|downregulation of Wnt receptor signaling pathway involved in DA neurogenesis from midbrain floor plate|down-regulation of frizzled signalling pathway involved in mDA neuron differentiation|negative regulation of Wnt receptor signaling pathway involved in midbrain dopaminergic neuron production|down-regulation of Wg signaling pathway involved in midbrain dopaminergic neuron differentiation|downregulation of Wingless signalling pathway involved in midbrain dopaminergic neuron production|down regulation of Wg signalling pathway involved in midbrain DA neurogenesis|inhibition of Wnt receptor signaling pathway involved in midbrain DA neurogenesis|downregulation of Wg signaling pathway involved in midbrain dopaminergic neuron differentiation|downregulation of Wg signaling pathway involved in midbrain DA neurogenesis|inhibition of Wnt receptor signalling pathway involved in DA neurogenesis from midbrain floor plate|down-regulation of Wingless signalling pathway involved in mDA neuron differentiation|downregulation of Wg signaling pathway involved in midbrain dopaminergic neuron production|down-regulation of Wnt receptor signalling pathway involved in DA neurogenesis from midbrain floor plate|negative regulation of Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation|downregulation of Wnt-activated signaling pathway involved in midbrain dopaminergic neuron differentiation|down-regulation of Wnt signaling pathway involved in mDA neuron differentiation|downregulation of frizzled signaling pathway involved in DA neurogenesis from midbrain floor plate|down-regulation of Wnt receptor signaling pathway involved in mDA neuron differentiation|inhibition of Wg signalling pathway involved in midbrain dopaminergic neuron production|downregulation of Wg signalling pathway involved in DA neurogenesis from midbrain floor plate|inhibition of frizzled signalling pathway involved in midbrain DA neurogenesis|downregulation of Wnt receptor signalling pathway involved in midbrain DA neurogenesis|negative regulation of Wg signalling pathway involved in DA neurogenesis from midbrain floor plate|down regulation of Wg signalling pathway involved in midbrain dopaminergic neuron production|inhibition of Wg signaling pathway involved in mDA neuron differentiation|inhibition of Wg signaling pathway involved in midbrain DA neurogenesis|inhibition of Wnt signaling pathway involved in DA neurogenesis from midbrain floor plate|inhibition of Wnt-activated signaling pathway involved in midbrain dopaminergic neuron differentiation|negative regulation of Wingless signalling pathway involved in midbrain DA neurogenesis|down regulation of frizzled signalling pathway involved in midbrain dopaminergic neuron production|down regulation of Wg signaling pathway involved in midbrain dopaminergic neuron differentiation|inhibition of Wnt receptor signaling pathway involved in midbrain dopaminergic neuron production|downregulation of frizzled signaling pathway involved in midbrain dopaminergic neuron production|negative regulation of Wnt receptor signaling pathway involved in mDA neuron differentiation|inhibition of Wg signalling pathway involved in mDA neuron differentiation|down-regulation of Wingless signalling pathway involved in midbrain dopaminergic neuron differentiation|down-regulation of frizzled signalling pathway involved in midbrain dopaminergic neuron differentiation|down-regulation of frizzled signaling pathway involved in midbrain DA neurogenesis|down regulation of Wnt receptor signalling pathway involved in midbrain dopaminergic neuron production|downregulation of Wingless signalling pathway involved in midbrain DA neurogenesis|inhibition of Wnt-activated signaling pathway involved in midbrain DA neurogenesis|down regulation of frizzled signalling pathway involved in midbrain DA neurogenesis|down-regulation of Wnt receptor signalling pathway involved in midbrain dopaminergic neuron differentiation							bf	2016-09-07T10:03:44Z					biological_process											owl:Class	
GO:0045149	biolink:NamedThing	acetoin metabolic process	The chemical reactions and pathways involving acetoin, 3-hydroxy-2-butanone, often as part of a fermentation pathway or for use as a carbon source.	tmpzr1t_l9r_go_relaxed.owl	acetoin metabolism													biological_process											owl:Class	
GO:0044375	biolink:NamedThing	regulation of peroxisome size	Any process that modulates the volume of a peroxisome, a small, membrane-bounded organelle that uses dioxygen (O2) to oxidize organic molecules.	tmpzr1t_l9r_go_relaxed.owl								jl	2011-12-01T04:37:59Z					biological_process											owl:Class	
GO:0042795	biolink:NamedThing	snRNA transcription by RNA polymerase II	The synthesis of small nuclear RNA (snRNA) from a DNA template by RNA Polymerase II (Pol II), originating at a Pol II promoter.	tmpzr1t_l9r_go_relaxed.owl	snRNA transcription from RNA polymerase II promoter|snRNA transcription from Pol II promoter	https://github.com/geneontology/go-ontology/issues/14854												biological_process											owl:Class	
GO:0043422	biolink:NamedThing	protein kinase B binding	Binding to protein kinase B, an intracellular kinase that is important in regulating glucose metabolism.	tmpzr1t_l9r_go_relaxed.owl	Akt binding|PKB binding													molecular_function											owl:Class	
GO:0032739	biolink:NamedThing	positive regulation of interleukin-16 production	Any process that activates or increases the frequency, rate, or extent of interleukin-16 production.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of interleukin-16 production|activation of interleukin-16 production|positive regulation of IL-16 production|stimulation of interleukin-16 production|upregulation of interleukin-16 production|up regulation of interleukin-16 production|positive regulation of interleukin-16 biosynthetic process											GO:0045377		biological_process											owl:Class	
GO:0009064	biolink:NamedThing	glutamine family amino acid metabolic process	The chemical reactions and pathways involving amino acids of the glutamine family, comprising arginine, glutamate, glutamine and proline.	tmpzr1t_l9r_go_relaxed.owl	glutamine family amino acid metabolism													biological_process											owl:Class	
GO:0102342	biolink:NamedThing	3-oxo-cerotoyl-CoA reductase activity	Catalysis of the reaction: (R)-3-hydroxycerotoyl-CoA + NADP <=> 3-oxohexacosanoyl-CoA + NADPH + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-13301|EC:1.1.1.330									molecular_function											owl:Class	
GO:0000973	biolink:NamedThing	posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery	The chromosome organization process in which the DNA sequence containing a gene transcribed by RNA polymerase II is maintained in a specific location at the nuclear periphery even after transcription has been repressed.	tmpzr1t_l9r_go_relaxed.owl								krc	2009-09-10T12:28:04Z					biological_process											owl:Class	
GO:0000972	biolink:NamedThing	transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery	The chromosome organization process in which the DNA sequence containing a gene transcribed by RNA polymerase II is maintained in a specific location at the nuclear periphery. In S. cerevisiae, this process involves cis-acting DNA sequences such as the TATA box and upstream activating sequence (UAS) elements, trans-acting transcriptional activators, and also the 3'-UTR of the transcript.	tmpzr1t_l9r_go_relaxed.owl								krc	2009-09-10T12:25:11Z					biological_process											owl:Class	
GO:0071448	biolink:NamedThing	cellular response to alkyl hydroperoxide	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alkyl hydroperoxide stimulus. Alkyl hydroperoxides are monosubstitution products of hydrogen peroxide, HOOH, where the substituent is an alkyl group.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-12-16T04:17:52Z					biological_process											owl:Class	
GO:0071447	biolink:NamedThing	cellular response to hydroperoxide	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydroperoxide stimulus. Hydroperoxides are monosubstitution products of hydrogen peroxide, HOOH.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-12-16T04:16:42Z					biological_process											owl:Class	
GO:0106288	biolink:NamedThing	regulation of deadenylation-dependent decapping of nuclear-transcribed mRNA	Any process that modulates the frequency, rate or extent of deadenylation-dependent decapping of nuclear-transcribed mRNA.	tmpzr1t_l9r_go_relaxed.owl								hjd	2020-08-13T17:06:31Z					biological_process											owl:Class	
GO:0047704	biolink:NamedThing	bile-salt sulfotransferase activity	Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + taurolithocholate = adenosine 3',5'-bisphosphate + taurolithocholate sulfate.	tmpzr1t_l9r_go_relaxed.owl	glycolithocholate sulfotransferase activity|BAST I activity|bile acid:3'-phosphoadenosine-5'-phosphosulfate sulfotransferase activity|bile salt:3'phosphoadenosine-5'-phosphosulfate:sulfotransferase activity|3'-phosphoadenylyl-sulfate:glycolithocholate sulfotransferase activity|bile-salt sulphotransferase activity|bile acid sulfotransferase I activity				EC:2.8.2.14|MetaCyc:BILE-SALT-SULFOTRANSFERASE-RXN|RHEA:14013									molecular_function											owl:Class	
GO:0047075	biolink:NamedThing	2,5-dihydroxypyridine 5,6-dioxygenase activity	Catalysis of the reaction: H2O + O2 + 2,5-dihydroxypyridine = formate + maleamate.	tmpzr1t_l9r_go_relaxed.owl	pyridine-2,5-diol dioxygenase activity|2,5-dihydroxypyridine:oxygen 5,6-oxidoreductase activity|2,5-dihydroxypyridine oxygenase activity				EC:1.13.11.9|RHEA:27522|UM-BBD_reactionID:r1443|MetaCyc:1.13.11.9-RXN									molecular_function											owl:Class	
GO:0016737	biolink:NamedThing	oxidoreductase activity, acting on reduced flavodoxin as donor	Catalysis of an oxidation-reduction (redox) reaction in which reduced flavodoxin acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.	tmpzr1t_l9r_go_relaxed.owl					EC:1.19.-.-									molecular_function											owl:Class	
GO:1901087	biolink:NamedThing	benzylpenicillin catabolic process	The chemical reactions and pathways resulting in the breakdown of benzylpenicillin.	tmpzr1t_l9r_go_relaxed.owl	penicillin G catabolic process|benzylpenicillin breakdown|benzylpenicillin degradation|benzylpenicillin catabolism|penicillin G degradation|penicillin G breakdown|penicillin G catabolism							yaf	2012-07-05T10:28:59Z					biological_process											owl:Class	
GO:0120231	biolink:NamedThing	DNA recombinase auxiliary factor complex	A protein complex that binds to a recombinase and incrseases its activity.	tmpzr1t_l9r_go_relaxed.owl	DNA recombinase accessory factor complex|DNA recombinase activator complex	https://github.com/geneontology/go-ontology/issues/19631						krc	2020-06-18T16:12:52Z					cellular_component											owl:Class	
GO:0051362	biolink:NamedThing	peptide cross-linking via 2-tetrahydropyridinyl-5-imidazolinone glycine	The formation of a 2-tetrahydropyridinyl-5-imidazolinone protein chromophore cross-link from the alpha-carboxyl carbon of residue n, a lysine, to the alpha-amino nitrogen of residue n+2, a glycine, and a dehydration to form a double bond to the alpha-amino nitrogen of residue n+1. This cross-linking is coupled with a dehydrogenation of residue n+1 to form a double bond between the alpha and beta carbons. In addition, the residue N lysine undergoes cyclization. The alpha-amino nitrogen is replaced by the epsilon-amino nitrogen, the peptide chain is broken, residue N-1 is released as an amide, and a double bond is formed between the alpha-carbon and the nitrogen so that a tetrahydropyridine ring results. This modification is found in the GFP-like fluorescent chromoprotein FP538 from the sea anemone Zoanthus species.	tmpzr1t_l9r_go_relaxed.owl	biosynthetic process of protein-protein cross-link via 2-tetrahydropyridinyl-5-imidazolinone glycine|biosynthesis of protein-protein cross-link via 2-tetrahydropyridinyl-5-imidazolinone glycine				RESID:AA0382	See also the biological process term 'peptidyl-tyrosine dehydrogenation ; GO:0018251'.								biological_process											owl:Class	
GO:1990222	biolink:NamedThing	ProVWX complex	The ProVWX complex belongs to the family of ATP-binding cassette (ABC) transporter proteins complexes. It consists of a cytoplasmic ATPase subunit ProV, a transmembrane subunit ProW and a periplasmic binding protein ProX. It is capable of translocating a wide variety of solute (e.g. glycine betaine) across the plasma membrane and is activated under osmotic stress conditions.	tmpzr1t_l9r_go_relaxed.owl	ATP-binding cassette (ABC) transporter complex ProVWX							bhm	2013-10-16T09:09:17Z					cellular_component											owl:Class	
GO:0039523	biolink:NamedThing	suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host mRNA transcription by directly inhibiting RNA polymerase II activity.	tmpzr1t_l9r_go_relaxed.owl	negative regulation by virus of host RNA polymerase II activity|inhibition of host RNA polymerase II by virus|suppression by virus of host RNA polymerase II activity|inhibition of host RNA polymerase II activity by virus	https://github.com/geneontology/go-ontology/issues/22148						bf	2011-06-22T04:38:59Z					biological_process											owl:Class	
GO:0005237	biolink:NamedThing	inhibitory extracellular ligand-gated ion channel activity	Enables the transmembrane transfer of an ion by a channel that opens when a specific extracellular inhibitory ligand has been bound by the channel complex or one of its constituent parts. Inhibitory ligands, such as GABA or glycine, open chloride-selective channels.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0006032	biolink:NamedThing	chitin catabolic process	The chemical reactions and pathways resulting in the breakdown of chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues.	tmpzr1t_l9r_go_relaxed.owl	chitin breakdown|chitin catabolism|chitin degradation|beta-1,4-linked N-acetylglucosamine catabolism|beta-1,4-linked N-acetylglucosamine catabolic process													biological_process											owl:Class	
GO:0097148	biolink:NamedThing	BCL-2 complex	A homodimeric protein complex consisting of BCL-2, a member of the Bcl-2 family of anti- and proapoptotic regulators.	tmpzr1t_l9r_go_relaxed.owl								pr	2011-08-02T01:51:16Z					cellular_component											owl:Class	
GO:0047531	biolink:NamedThing	2,5-diaminovalerate transaminase activity	Catalysis of the reaction: 2-oxoglutarate + ornithine = 5-amino-2-oxopentanoate + L-glutamate.	tmpzr1t_l9r_go_relaxed.owl	2,5-diaminopentanoate:2-oxoglutarate aminotransferase activity|2,5-diaminovalerate aminotransferase activity|diamino-acid transaminase activity|diamino acid aminotransferase activity|diamino-acid aminotransferase activity				EC:2.6.1.8|KEGG_REACTION:R03248|MetaCyc:25-DIAMINOVALERATE-AMINOTRANSFERASE-RXN|RHEA:16017									molecular_function											owl:Class	
GO:0102388	biolink:NamedThing	UDP-N,N'-diacetylbacillosamine 2-epimerase activity	Catalysis of the reaction: UDP-N,N'-diacetylbacillosamine + H2O <=> 2,4-diacetamido-2,4,6-trideoxy-alpha-D-mannopyranose + UDP + H+.	tmpzr1t_l9r_go_relaxed.owl					EC:3.2.1.184|RHEA:34491|MetaCyc:RXN-13574									molecular_function											owl:Class	
GO:0060801	biolink:NamedThing	negative regulation of trophoblast cell differentiation by transforming growth factor beta signaling pathway	The transforming growth factor signaling process that decreases the rate, frequency, or extent of trophoblast stem cells differentiating into the more mature cells of the trophoblast.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of trophoblast cell differentiation by transforming growth factor beta signalling pathway							dph	2009-08-06T01:24:24Z					biological_process											owl:Class	
GO:1901812	biolink:NamedThing	beta-carotene biosynthetic process	The chemical reactions and pathways resulting in the formation of beta-carotene.	tmpzr1t_l9r_go_relaxed.owl	beta-carotene anabolism|beta-carotene synthesis|beta-carotene formation|beta-carotene biosynthesis							yaf	2013-01-22T10:30:32Z					biological_process											owl:Class	
GO:0070789	biolink:NamedThing	metula development	The process whose specific outcome is the progression of metulae over time, from its formation to the mature structure. Metulae are elongated mononucleate cells that bud from the surface of the conidiophore tip.	tmpzr1t_l9r_go_relaxed.owl	development of primary sterigmata							mah	2009-07-08T01:33:46Z					biological_process											owl:Class	
GO:0031725	biolink:NamedThing	CXCR6 chemokine receptor binding	Binding to a CXCR6 chemokine receptor.	tmpzr1t_l9r_go_relaxed.owl	CXCR6 chemokine receptor ligand|bonzo receptor binding|STRL33 receptor binding													molecular_function											owl:Class	
GO:0060646	biolink:NamedThing	internal mammary gland bud epithelial cell differentiation	The process in which a relatively unspecialized epithelial cell of the mammary placode becomes an internal epithelial cell of the mammary gland bud. Internal cells are small and of irregular shape.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-05-29T08:10:48Z					biological_process											owl:Class	
GO:0071299	biolink:NamedThing	cellular response to vitamin A	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin A stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to retinol							mah	2009-12-10T04:29:30Z					biological_process											owl:Class	
GO:0072589	biolink:NamedThing	box H/ACA scaRNP complex	A box H/ACA RNP complex that is located in the Cajal body of the nucleoplasm. In higher eukaryotes, box H/ACA RNP located in Cajal bodies mediate pseudouridylation of spliceosomal snRNAs.	tmpzr1t_l9r_go_relaxed.owl	nucleoplasmic box H/ACA RNP pseudouridylase complex							mah	2011-02-10T02:47:17Z					cellular_component											owl:Class	
GO:0047926	biolink:NamedThing	geranyl-diphosphate cyclase activity	Catalysis of the reaction: geranyl diphosphate = (2S)-bornyl diphosphate.	tmpzr1t_l9r_go_relaxed.owl	bornyl diphosphate synthase activity|bornyl pyrophosphate synthase activity|bornyl pyrophosphate synthetase activity|(+)-bornylpyrophosphate cyclase activity|(+)-bornyl-diphosphate lyase (decyclizing)				EC:5.5.1.8|KEGG_REACTION:R02007|RHEA:18209|MetaCyc:GERANYL-DIPHOSPHATE-CYCLASE-RXN									molecular_function											owl:Class	
GO:0019495	biolink:NamedThing	proline catabolic process to 2-oxoglutarate	The chemical reactions and pathways resulting in the breakdown of proline into other compounds, including 2-oxoglutarate.	tmpzr1t_l9r_go_relaxed.owl	proline catabolism to 2-ketoglutarate|proline catabolism to alpha-oxoglutarate|proline degradation to 2-oxoglutarate|proline breakdown to 2-oxoglutarate|proline catabolic process to 2-ketoglutarate|proline catabolic process to alpha-ketoglutarate|proline catabolic process to alpha-oxoglutarate|proline catabolism to alpha-ketoglutarate													biological_process											owl:Class	
GO:0035779	biolink:NamedThing	angioblast cell differentiation	The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of an angioblast cell. Angioblasts are one of the two products formed from hemangioblast cells (the other being pluripotent hemopoietic stem cells).	tmpzr1t_l9r_go_relaxed.owl	angioblastic mesenchymal cell differentiation							bf	2011-04-04T11:10:38Z					biological_process											owl:Class	
GO:0003237	biolink:NamedThing	sinus venosus formation	The developmental process pertaining to the initial formation of the sinus venosus from unspecified parts. The sinus venosus is a heart chamber attached to the atrium on the venous side of the embryonic heart.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-10-13T11:18:34Z					biological_process											owl:Class	
GO:0046581	biolink:NamedThing	intercellular canaliculus	An extremely narrow tubular channel located between adjacent cells. An instance of this is the secretory canaliculi occurring between adjacent parietal cells in the gastric mucosa of vertebrates.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0005315	biolink:NamedThing	inorganic phosphate transmembrane transporter activity	Enables the transfer of a inorganic phosphate from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters.	tmpzr1t_l9r_go_relaxed.owl												GO:0005317		molecular_function											owl:Class	
GO:1903508	biolink:NamedThing	positive regulation of nucleic acid-templated transcription	Any process that activates or increases the frequency, rate or extent of nucleic acid-templated transcription.	tmpzr1t_l9r_go_relaxed.owl	up regulation of nucleic acid-templated transcription|up-regulation of nucleic acid-templated transcription|upregulation of nucleic acid-templated transcription|activation of nucleic acid-templated transcription							pr	2014-10-01T14:45:04Z					biological_process											owl:Class	
GO:0031625	biolink:NamedThing	ubiquitin protein ligase binding	Binding to a ubiquitin protein ligase enzyme, any of the E3 proteins.	tmpzr1t_l9r_go_relaxed.owl	ubiquitin ligase binding													molecular_function											owl:Class	
GO:1904734	biolink:NamedThing	positive regulation of electron transfer activity	Any process that activates or increases the frequency, rate or extent of electron transfer activity.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of amicyanin|up regulation of iron-sulfur electron transfer carrier|activation of dicluster bacterial-type ferredoxin|up regulation of 2Fe-2S electron transfer carrier|activation of polyferredoxin|positive regulation of electron acceptor activity|up regulation of electron acceptor activity|up-regulation of electron transfer flavoprotein, group II|activation of electron transfer flavoprotein|activation of electron carrier, chlorophyll electron transport system|up regulation of azurin|activation of rubredoxin|upregulation of 2Fe-2S electron transfer carrier|up regulation of redox-active disulfide bond electron carrier|up regulation of thioredoxin-like 2Fe-2S ferredoxin|upregulation of monocluster bacterial-type ferredoxin|upregulation of adrenodoxin-type ferredoxin|positive regulation of electron transfer flavoprotein, group II|positive regulation of electron donor activity|up regulation of electron transporter activity|up-regulation of adrenodoxin-type ferredoxin|upregulation of bacterial-type ferredoxin|up regulation of polyferredoxin|activation of iron-sulfur electron transfer carrier|up regulation of electron transfer flavoprotein, group II|up regulation of copper electron carrier|up-regulation of dicluster bacterial-type ferredoxin|positive regulation of small blue copper electron carrier|up-regulation of mononuclear iron electron carrier|up-regulation of electron carrier, chlorophyll electron transport system|upregulation of electron transfer flavoprotein|activation of bacterial-type ferredoxin|up regulation of chloroplast-type ferredoxin|activation of thioredoxin-like 2Fe-2S ferredoxin|up-regulation of copper electron carrier|positive regulation of copper electron carrier|up-regulation of chloroplast-type ferredoxin|activation of high-potential iron-sulfur carrier|up regulation of amicyanin|positive regulation of 3Fe-4S/4Fe-4S electron transfer carrier|upregulation of electron acceptor activity|activation of electron acceptor activity|upregulation of polyferredoxin|activation of azurin|activation of electron carrier activity|up-regulation of electron donor activity|up regulation of adrenodoxin-type ferredoxin|upregulation of electron carrier activity|up regulation of rubredoxin|up regulation of high-potential iron-sulfur carrier|upregulation of amicyanin|up-regulation of electron acceptor activity|activation of electron donor activity|upregulation of electron carrier, chlorophyll electron transport system|up regulation of mononuclear iron electron carrier|positive regulation of polyferredoxin|activation of 2Fe-2S electron transfer carrier|positive regulation of rubredoxin|up-regulation of electron transporter activity|upregulation of electron transfer flavoprotein, group II|positive regulation of electron carrier, chlorophyll electron transport system|up regulation of small blue copper electron carrier|positive regulation of thioredoxin-like 2Fe-2S ferredoxin|up regulation of electron carrier, chlorophyll electron transport system|positive regulation of mononuclear iron electron carrier|positive regulation of azurin|activation of electron transfer flavoprotein, group II|up regulation of electron donor activity|positive regulation of electron transfer flavoprotein|activation of redox-active disulfide bond electron carrier|activation of adrenodoxin-type ferredoxin|positive regulation of chloroplast-type ferredoxin|up-regulation of polyferredoxin|upregulation of rubredoxin|up-regulation of rubredoxin|up-regulation of amicyanin|up-regulation of azurin|up-regulation of monocluster bacterial-type ferredoxin|positive regulation of iron-sulfur electron transfer carrier|activation of 3Fe-4S/4Fe-4S electron transfer carrier|activation of amicyanin|upregulation of 3Fe-4S/4Fe-4S electron transfer carrier|up-regulation of high-potential iron-sulfur carrier|up-regulation of thioredoxin-like 2Fe-2S ferredoxin|positive regulation of monocluster bacterial-type ferredoxin|upregulation of mononuclear iron electron carrier|positive regulation of bacterial-type ferredoxin|up regulation of bacterial-type ferredoxin|upregulation of electron transporter activity|up-regulation of 2Fe-2S electron transfer carrier|upregulation of chloroplast-type ferredoxin|positive regulation of dicluster bacterial-type ferredoxin|positive regulation of electron transfer flavoprotein, group I|positive regulation of electron transporter activity|up-regulation of redox-active disulfide bond electron carrier|up-regulation of electron transfer flavoprotein, group I|up regulation of 3Fe-4S/4Fe-4S electron transfer carrier|activation of electron transfer flavoprotein, group I|upregulation of iron-sulfur electron transfer carrier|up regulation of monocluster bacterial-type ferredoxin|upregulation of redox-active disulfide bond electron carrier|upregulation of copper electron carrier|upregulation of dicluster bacterial-type ferredoxin|upregulation of thioredoxin-like 2Fe-2S ferredoxin|upregulation of azurin|positive regulation of 2Fe-2S electron transfer carrier|activation of copper electron carrier|activation of mononuclear iron electron carrier|up-regulation of electron transfer flavoprotein|activation of electron transporter activity|up regulation of electron transfer flavoprotein, group I|upregulation of electron transfer flavoprotein, group I|upregulation of small blue copper electron carrier|up-regulation of electron carrier activity|up-regulation of bacterial-type ferredoxin|upregulation of electron donor activity|positive regulation of adrenodoxin-type ferredoxin|up regulation of electron transfer flavoprotein|up regulation of dicluster bacterial-type ferredoxin|upregulation of high-potential iron-sulfur carrier|up-regulation of iron-sulfur electron transfer carrier|activation of chloroplast-type ferredoxin|activation of monocluster bacterial-type ferredoxin|up regulation of electron carrier activity|up-regulation of 3Fe-4S/4Fe-4S electron transfer carrier|up-regulation of small blue copper electron carrier|activation of small blue copper electron carrier|positive regulation of high-potential iron-sulfur carrier|positive regulation of redox-active disulfide bond electron carrier							lb	2015-10-15T07:51:32Z					biological_process											owl:Class	
GO:0017051	biolink:NamedThing	retinol dehydratase activity	Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + retinol = adenosine 3',5'-bisphosphate + anhydroretinol.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0006228	biolink:NamedThing	UTP biosynthetic process	The chemical reactions and pathways resulting in the formation of UTP, uridine (5'-)triphosphate.	tmpzr1t_l9r_go_relaxed.owl	UTP synthesis|UTP formation|UTP biosynthesis|UTP anabolism													biological_process											owl:Class	
GO:0046051	biolink:NamedThing	UTP metabolic process	The chemical reactions and pathways involving UTP, uridine (5'-)triphosphate.	tmpzr1t_l9r_go_relaxed.owl	UTP metabolism													biological_process											owl:Class	
GO:0018125	biolink:NamedThing	peptidyl-cysteine methylation	The methylation of peptidyl-cysteine to form peptidyl-S-methyl-L-cysteine.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0234									biological_process											owl:Class	
GO:0032142	biolink:NamedThing	single guanine insertion binding	Binding to a double-stranded DNA region containing a single guanine insertion or a deletion that results in an unpaired guanine.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1903767	biolink:NamedThing	sweet taste receptor complex	A protein complex which is capable of sweet taste receptor activity.	tmpzr1t_l9r_go_relaxed.owl								rl	2014-12-22T16:49:24Z					cellular_component											owl:Class	
GO:0050933	biolink:NamedThing	early stripe melanocyte differentiation	The process in which a relatively unspecialized cell acquires the specialized features of an early stripe melanocyte (ESM). In zebrafish, ESMs develop during the first phase (2-3 weeks of development) of the larva to adult transition (2-4 weeks of development).	tmpzr1t_l9r_go_relaxed.owl	early stripe melanocyte cell differentiation|early stripe melanophore differentiation													biological_process											owl:Class	
GO:1905554	biolink:NamedThing	negative regulation of vessel branching	Any process that stops, prevents or reduces the frequency, rate or extent of blood vessel branching.	tmpzr1t_l9r_go_relaxed.owl	down regulation of patterning of blood vessels|downregulation of branching involved in blood vessel morphogenesis|inhibition of branching involved in blood vessel morphogenesis|negative regulation of branching involved in blood vessel morphogenesis|down-regulation of branching involved in blood vessel morphogenesis|down-regulation of patterning of blood vessels|inhibition of patterning of blood vessels|down regulation of branching involved in blood vessel morphogenesis|downregulation of patterning of blood vessels							nc	2016-10-12T14:19:41Z					biological_process											owl:Class	
GO:0039579	biolink:NamedThing	suppression by virus of host ISG15-protein conjugation	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host ubiquitin-like protein ISG15 conjugation to a susbtrate. ISG15 is a ubiquitin-like protein that is conjugated to lysine residues on various target proteins. Viruses escape from the antiviral activity of ISG15 by using different mechanisms; the influenza B virus NS1 protein for instance blocks the covalent linkage of ISG15 to its target proteins by directly interacting with ISG15. The papain-like protease from the coronavirus cleaves ISG15 derivatives.	tmpzr1t_l9r_go_relaxed.owl	suppression by virus of host ISG15 activity	https://github.com/geneontology/go-ontology/issues/22157						bf						biological_process											owl:Class	
GO:0097705	biolink:NamedThing	vascular endothelial cell response to pulsatile fluid shear stress	Any response to pulsatile fluid shear stress that occurs in a vascular endothelial cell.	tmpzr1t_l9r_go_relaxed.owl	blood vessel endothelial cell response to pulsatile fluid shear stress							pr	2016-01-27T14:22:44Z					biological_process											owl:Class	
GO:0019462	biolink:NamedThing	glutamine catabolic process to fumarate, using glutaminase	The chemical reactions and pathways resulting in the breakdown of glutamine into fumarate, beginning with conversion of glutamine into glutamate catalyzed by the enzyme glutaminase (EC:3.5.1.2).	tmpzr1t_l9r_go_relaxed.owl	glutamate catabolic process to fumarate, using glutaminase|glutamine breakdown to fumarate, using glutaminase|glutamine degradation to fumarate, using glutaminase				MetaCyc:GLUTAMINDEG-PWY									biological_process											owl:Class	
GO:0090129	biolink:NamedThing	positive regulation of synapse maturation	Any process that increases the extent of synapse maturation, the process that organizes a synapse so that it attains its fully functional state.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-12-07T03:00:58Z					biological_process											owl:Class	
GO:1905360	biolink:NamedThing	GTPase complex	A protein complex which is capable of GTPase activity.	tmpzr1t_l9r_go_relaxed.owl	RASH-SOS1 complex|HRAS-SOS1 complex					An example of this is HRAS in human (P01112) in PMID:9178006 (inferred from direct assay).		bhm	2016-08-11T15:34:44Z					cellular_component											owl:Class	
GO:0050261	biolink:NamedThing	ribose isomerase activity	Catalysis of the reaction: ribofuranose = D-ribulose.	tmpzr1t_l9r_go_relaxed.owl	D-ribose aldose-ketose-isomerase activity|D-ribose isomerase activity|D-ribose ketol-isomerase activity				RHEA:20796|KEGG_REACTION:R01081|MetaCyc:RIBOSE-ISOMERASE-RXN|EC:5.3.1.20									molecular_function											owl:Class	
GO:0102374	biolink:NamedThing	ursolic aldehyde 28-monooxygenase activity	Catalysis of the reaction: ursolic aldehyde + NADPH + O2 + H+ <=> ursolic acid + NADP + H2O.	tmpzr1t_l9r_go_relaxed.owl					EC:1.14.14.126|MetaCyc:RXN-13502									molecular_function											owl:Class	
GO:0047919	biolink:NamedThing	GDP-mannose 6-dehydrogenase activity	Catalysis of the reaction: GDP-alpha-D-mannose + H(2)O + 2 NAD(+) = GDP-D-mannuronate + 3 H(+) + 2 NADH.	tmpzr1t_l9r_go_relaxed.owl	GDP mannose dehydrogenase activity|guanosine diphospho-D-mannose dehydrogenase activity|guanosine diphosphomannose dehydrogenase activity|GDPmannose 6-dehydrogenase activity|GDP-D-mannose:NAD+ 6-oxidoreductase activity				RHEA:21728|MetaCyc:GDP-MANNOSE-6-DEHYDROGENASE-RXN|KEGG_REACTION:R00880|EC:1.1.1.132									molecular_function											owl:Class	
GO:1900709	biolink:NamedThing	positive regulation of tensidol A biosynthetic process	Any process that activates or increases the frequency, rate or extent of tensidol A biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	up regulation of tensidol A biosynthetic process|positive regulation of tensidol A biosynthesis|activation of tensidol A formation|positive regulation of tensidol A anabolism|activation of tensidol A anabolism|positive regulation of tensidol A synthesis|activation of tensidol A synthesis|upregulation of tensidol A biosynthetic process|up regulation of tensidol A biosynthesis|up-regulation of tensidol A anabolism|positive regulation of tensidol A formation|up regulation of tensidol A formation|upregulation of tensidol A biosynthesis|up regulation of tensidol A synthesis|activation of tensidol A biosynthesis|activation of tensidol A biosynthetic process|upregulation of tensidol A synthesis|up-regulation of tensidol A formation|up-regulation of tensidol A biosynthetic process|upregulation of tensidol A formation|up regulation of tensidol A anabolism|up-regulation of tensidol A biosynthesis|upregulation of tensidol A anabolism|up-regulation of tensidol A synthesis							di	2012-05-22T05:02:12Z					biological_process											owl:Class	
GO:0046891	biolink:NamedThing	peptidyl-cysteine S-carbamoylation	The carbamoylation of peptidyl-cysteine to form peptidyl-S-carbamoyl-L-cysteine.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0332									biological_process											owl:Class	
GO:0052902	biolink:NamedThing	spermidine:oxygen oxidoreductase (3-aminopropanal-forming) activity	Catalysis of the reaction: H(2)O + O(2) + spermidine = 3-aminopropanal + H(2)O(2) + putrescine.	tmpzr1t_l9r_go_relaxed.owl	polyamine oxidase activity|non-specific polyamine oxidase activity|N(1)-acetylpolyamine oxidase activity				MetaCyc:RXN-10461|MetaCyc:RXN-12089|EC:1.5.3.13|KEGG_REACTION:R09077|RHEA:25808|EC:1.5.3.17									molecular_function											owl:Class	
GO:0008184	biolink:NamedThing	glycogen phosphorylase activity	Catalysis of the reaction: glycogen + phosphate = maltodextrin + alpha-D-glucose 1-phosphate.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:GLYCOPHOSPHORYL-RXN|Reactome:R-HSA-71590|Reactome:R-HSA-453339|Reactome:R-HSA-453358|Reactome:R-HSA-71515									molecular_function											owl:Class	
GO:0044717	biolink:NamedThing	8-hydroxy-dADP phosphatase activity	Catalysis of the reaction: 8-hydroxy-dADP + H2O = 8-hydroxy-dAMP + phosphate.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-2395965			jl	2012-10-18T13:33:32Z					molecular_function											owl:Class	
GO:0102199	biolink:NamedThing	nitric oxide reductase activity (NAD(P)H-dependent) activity	Catalysis of the reaction: dinitrogen oxide + H2O + NAD(P) = 2 nitric oxide + H+ + NAD(P)H.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-12112|EC:1.7.1.14									molecular_function											owl:Class	
GO:0018481	biolink:NamedThing	4-hydroxymuconic-semialdehyde dehydrogenase activity	Catalysis of the reaction: <stereo>cis,trans</stereo>-4-hydroxymuconate semialdehyde + H(2)O + NAD(+) = 2 H(+) + maleylacetate + NADH.	tmpzr1t_l9r_go_relaxed.owl	4-hydroxymuconic-semialdehyde:NAD+ oxidoreductase activity				UM-BBD_reactionID:r0229|EC:1.2.1.61|RHEA:22420|MetaCyc:1.2.1.61-RXN|KEGG_REACTION:R05236									molecular_function											owl:Class	
GO:0018445	biolink:NamedThing	prothoracicotrophic hormone activity	The action characteristic of prothoracicotrophic hormone, a peptide hormone that is secreted by the brain and, upon receptor binding, acts on the prothoracic gland to stimulate the release of ecdysone in insects.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0032976	biolink:NamedThing	release of matrix enzymes from mitochondria	The process in which enzymes, such as aspartate aminotransferase, are enabled to move from the mitochondrial matrix into the cytosol, as part of the apoptotic process.	tmpzr1t_l9r_go_relaxed.owl	release of aspartate aminotransferase from mitochondria|mAST release from mitochondria					Annotation to this term should be done with caution, particularly if the mechanism is not well clarified.								biological_process											owl:Class	
GO:0043158	biolink:NamedThing	heterocyst differentiation	The process in which a relatively unspecialized cell acquires specialized features of a heterocyst, a differentiated cell in certain cyanobacteria whose purpose is to fix nitrogen.	tmpzr1t_l9r_go_relaxed.owl	heterocyst cell differentiation|heterocyst biosynthesis|heterocyst formation													biological_process											owl:Class	
GO:1990027	biolink:NamedThing	S bouton	Synaptic bouton found in the ventral horn of the spinal cord. S boutons range in diameter from 0.5 to 8 um and contain spherical synaptic vesicles.	tmpzr1t_l9r_go_relaxed.owl					NIF_Subcellular:nlx_subcell_100207			pr	2013-02-06T10:35:12Z					cellular_component											owl:Class	
GO:1990699	biolink:NamedThing	palmitoleyl hydrolase activity	Catalysis of a hydrolase reaction that removes a palmitoleyl moiety, a 16-carbon monounsaturated fatty acid (C16:1), from some substrate.	tmpzr1t_l9r_go_relaxed.owl								sp	2015-03-13T09:00:05Z					molecular_function											owl:Class	
GO:0051665	biolink:NamedThing	membrane raft localization	Any process in which membrane rafts are transported to, or maintained in, a specific location. Membrane rafts are small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes.	tmpzr1t_l9r_go_relaxed.owl	lipid raft localization|establishment and maintenance of membrane raft localization|membrane raft localisation													biological_process											owl:Class	
GO:1904054	biolink:NamedThing	regulation of cholangiocyte proliferation	Any process that modulates the frequency, rate or extent of cholangiocyte proliferation.	tmpzr1t_l9r_go_relaxed.owl	regulation of hepatoblast proliferation							sl	2015-03-18T17:56:14Z					biological_process											owl:Class	
GO:0140640	biolink:NamedThing	catalytic activity, acting on a nucleic acid	Catalytic activity that acts to modify a nucleic acid.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/21402						pg	2021-05-11T06:31:07Z					molecular_function											owl:Class	
GO:0043758	biolink:NamedThing	acetate-CoA ligase (ADP-forming) activity	Catalysis of the reaction: ATP + acetate + CoA = ADP + phosphate + acetyl-CoA.	tmpzr1t_l9r_go_relaxed.owl	acetate thiokinase activity|acetate--CoA ligase (ADP-forming) activity|acetyl-CoA synthetase (ADP-forming) activity|acetyl coenzyme A synthetase (adenosine diphosphate-forming)|aryl-CoA synthetase (ADP-forming) activity|acetate:CoA ligase (ADP-forming)				EC:6.2.1.13|RHEA:15081|MetaCyc:ACETATE--COA-LIGASE-ADP-FORMING-RXN							GO:0043762		molecular_function											owl:Class	
GO:1902849	biolink:NamedThing	positive regulation of neuronal signal transduction	Any process that activates or increases the frequency, rate or extent of neuronal signal transduction.	tmpzr1t_l9r_go_relaxed.owl	upregulation of neuronal signal transduction|up-regulation of neuronal signal transduction|activation of neuronal signal transduction|up regulation of neuronal signal transduction							sjp	2014-04-02T10:11:24Z					biological_process											owl:Class	
GO:0050437	biolink:NamedThing	(-)-endo-fenchol synthase activity	Catalysis of the reaction: geranyl diphosphate + H(2)O = (-)-endo-fenchol + diphosphate.	tmpzr1t_l9r_go_relaxed.owl	(-)-endo-fenchol cyclase activity|geranyl-diphosphate diphosphate-lyase [cyclizing, (-)-endo-fenchol-forming]|geranyl pyrophosphate:(-)-endo-fenchol cyclase activity				RHEA:20565|MetaCyc:4.2.3.10-RXN|KEGG_REACTION:R02004|EC:4.2.3.10									molecular_function											owl:Class	
GO:0042861	biolink:NamedThing	achromobactin biosynthetic process	The chemical reactions and pathways resulting in the formation of achromobactin, a citrate siderophore.	tmpzr1t_l9r_go_relaxed.owl	achromobactin anabolism|achromobactin formation|achromobactin synthesis|achromobactin biosynthesis											GO:0031182|GO:0031181		biological_process											owl:Class	
GO:0060249	biolink:NamedThing	anatomical structure homeostasis	A homeostatic process involved in the maintenance of an internal steady state within a defined anatomical structure of an organism, including control of cellular proliferation and death and control of metabolic function. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome.	tmpzr1t_l9r_go_relaxed.owl	anatomical structure maintenance													biological_process											owl:Class	
GO:0010736	biolink:NamedThing	serum response element binding	Binding to a serum response element (SRE), a short sequence with dyad symmetry found in the promoters of some of the cellular immediate-early genes, regulated by serum.	tmpzr1t_l9r_go_relaxed.owl						Note that as agreed during the transcription overhaul, terms specifying binding to specific transcription regulatory motifs are no longer being created. The level of specificity GO has decided to go to is the "core promoter", "core promoter proximal region" and "enhancer". To capture more detail, please consider using column 16.								molecular_function											owl:Class	
GO:1990846	biolink:NamedThing	ribonucleoside-diphosphate reductase inhibitor activity	Binds to and stops, prevents or reduces the activity of ribonucleoside-diphosphate reductase.	tmpzr1t_l9r_go_relaxed.owl								vw	2015-09-04T18:13:15Z					molecular_function											owl:Class	
GO:1903033	biolink:NamedThing	positive regulation of microtubule plus-end binding	Any process that activates or increases the frequency, rate or extent of microtubule plus-end binding.	tmpzr1t_l9r_go_relaxed.owl	up regulation of microtubule plus-end binding|activation of microtubule plus-end binding|up-regulation of microtubule plus-end binding|upregulation of microtubule plus-end binding							hjd	2014-05-16T18:38:38Z					biological_process											owl:Class	
GO:1903031	biolink:NamedThing	regulation of microtubule plus-end binding	Any process that modulates the frequency, rate or extent of microtubule plus-end binding.	tmpzr1t_l9r_go_relaxed.owl								hjd	2014-05-16T18:38:26Z					biological_process											owl:Class	
GO:0023022	biolink:NamedThing	termination of T cell signal transduction	The signaling process in which T cell signal transduction is brought to an end rather than being reversibly modulated.	tmpzr1t_l9r_go_relaxed.owl									2010-02-16T09:30:50Z					biological_process											owl:Class	
GO:1904914	biolink:NamedThing	negative regulation of establishment of protein-containing complex localization to telomere	Any process that stops, prevents or reduces the frequency, rate or extent of establishment of the localization of a protein-containing macromolecular complex to a telomere.	tmpzr1t_l9r_go_relaxed.owl	inhibition of establishment of macromolecular complex localization to telomere|down-regulation of establishment of macromolecular complex localisation to telomere|negative regulation of establishment of macromolecular complex localisation to telomere|downregulation of establishment of macromolecular complex localization to telomere|down-regulation of establishment of macromolecular complex localization to telomere|downregulation of establishment of macromolecular complex localisation to telomere|negative regulation of establishment of macromolecular complex localization to telomere|inhibition of establishment of macromolecular complex localisation to telomere|down regulation of establishment of macromolecular complex localization to telomere|down regulation of establishment of macromolecular complex localisation to telomere							rph	2016-01-19T10:38:29Z					biological_process											owl:Class	
GO:0031941	biolink:NamedThing	filamentous actin	A two-stranded helical polymer of the protein actin.	tmpzr1t_l9r_go_relaxed.owl	F-actin				Wikipedia:Actin	Note that this term refers only to the actin portion of a microfilament, and does not encompass associated proteins. See also the cellular component term 'actin filament ; GO:0005884'.								cellular_component											owl:Class	
GO:0047431	biolink:NamedThing	3-hydroxy-2-methylpyridine-4,5-dicarboxylate 4-decarboxylase activity	Catalysis of the reaction: 5-hydroxy-6-methylpyridine-3,4-dicarboxylate + H(+) = 5-hydroxy-6-methylpyridine-3-carboxylate + CO(2).	tmpzr1t_l9r_go_relaxed.owl	3-hydroxy-2-methylpyridine-4,5-dicarboxylate 4-carboxy-lyase (3-hydroxy-2-methylpyridine-5-carboxylate-forming)|3-hydroxy-2-methylpyridine-4,5-dicarboxylate 4-carboxy-lyase activity				EC:4.1.1.51|RHEA:13669|KEGG_REACTION:R03461|MetaCyc:4.1.1.51-RXN									molecular_function											owl:Class	
GO:0050465	biolink:NamedThing	nitroquinoline-N-oxide reductase activity	Catalysis of the reaction: 4-(hydroxyamino)quinoline N-oxide + 2 NAD(P)+ + H2O = 4-nitroquinoline N-oxide + 2 NAD(P)H + 2 H+.	tmpzr1t_l9r_go_relaxed.owl	NAD(P)H:4-nitroquinoline-N-oxide oxidoreductase activity|NAD(P)H2:4-nitroquinoline-N-oxide oxidoreductase activity|4NQO reductase activity|4-nitroquinoline 1-oxide reductase activity|4-(hydroxyamino)quinoline N-oxide:NADP+ oxidoreductase activity				MetaCyc:1.7.1.9-RXN|EC:1.7.1.9									molecular_function											owl:Class	
GO:0019467	biolink:NamedThing	ornithine catabolic process, by decarboxylation	The chemical reactions and pathways resulting in the breakdown of ornithine by decarboxylation.	tmpzr1t_l9r_go_relaxed.owl	ornithine breakdown, by decarboxylation|ornithine degradation, by decarboxylation				MetaCyc:ORNDEG-PWY									biological_process											owl:Class	
GO:0018593	biolink:NamedThing	4-chlorophenoxyacetate monooxygenase activity	Catalysis of the reaction: 4-chlorophenoxyacetate + 1/2 O2 = glyoxylate + 4-chlorophenol.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0281									molecular_function											owl:Class	
GO:0008294	biolink:NamedThing	calcium- and calmodulin-responsive adenylate cyclase activity	Catalysis of the reaction: ATP = 3',5'-cyclic AMP + diphosphate, stimulated by calcium-bound calmodulin.	tmpzr1t_l9r_go_relaxed.owl	calcium/calmodulin-responsive adenylate cyclase activity|calcium- and calmodulin-responsive adenylyl cyclase activity				Reactome:R-HSA-442715|Reactome:R-HSA-111930									molecular_function											owl:Class	
GO:0051908	biolink:NamedThing	double-stranded DNA 5'-3' exodeoxyribonuclease activity	Catalysis of the sequential cleavage of mononucleotides from a free 5' terminus of a double-stranded DNA molecule.	tmpzr1t_l9r_go_relaxed.owl	double-stranded DNA specific 5'-3' exodeoxyribonuclease activity													molecular_function											owl:Class	
GO:0070889	biolink:NamedThing	platelet alpha granule organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a platelet alpha granule. A platelet alpha granule is a secretory organelle found in blood platelets.	tmpzr1t_l9r_go_relaxed.owl	platelet alpha granule organisation|platelet alpha granule organization and biogenesis|platelet alpha-granule organization							mah	2009-08-28T10:43:31Z					biological_process											owl:Class	
GO:0046169	biolink:NamedThing	methanol biosynthetic process	The chemical reactions and pathways resulting in the formation of methanol, CH3-OH, a colorless, flammable, mobile, poisonous liquid, widely used as a solvent.	tmpzr1t_l9r_go_relaxed.owl	methanol synthesis|methanol anabolism|methanol biosynthesis|methanol formation													biological_process											owl:Class	
GO:0015330	biolink:NamedThing	high-affinity glutamine transmembrane transporter activity	Enables the transfer of glutamine from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.	tmpzr1t_l9r_go_relaxed.owl	high affinity glutamine transmembrane transporter activity|high affinity glutamine permease activity													molecular_function											owl:Class	
GO:0050999	biolink:NamedThing	regulation of nitric-oxide synthase activity	Any process that modulates the activity of the enzyme nitric-oxide synthase.	tmpzr1t_l9r_go_relaxed.owl	regulation of NOS activity|NOS regulator|nitric-oxide synthase regulator													biological_process											owl:Class	
GO:0021567	biolink:NamedThing	rhombomere 1 development	The process whose specific outcome is the progression of rhombomere 1 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0002588	biolink:NamedThing	positive regulation of antigen processing and presentation of peptide antigen via MHC class II	Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class II.	tmpzr1t_l9r_go_relaxed.owl	upregulation of antigen processing and presentation of peptide antigen via MHC class II|activation of antigen processing and presentation of peptide antigen via MHC class II|positive regulation of peptide antigen processing and presentation via MHC class II|up-regulation of antigen processing and presentation of peptide antigen via MHC class II|stimulation of antigen processing and presentation of peptide antigen via MHC class II|up regulation of antigen processing and presentation of peptide antigen via MHC class II													biological_process											owl:Class	
GO:1905823	biolink:NamedThing	negative regulation of mitotic sister chromatid arm separation	Any process that stops, prevents or reduces the frequency, rate or extent of mitotic sister chromatid arm separation.	tmpzr1t_l9r_go_relaxed.owl	down regulation of mitotic sister chromatid arm separation|inhibition of mitotic sister chromatid arm separation|down-regulation of mitotic sister chromatid arm separation|downregulation of mitotic sister chromatid arm separation							als	2017-01-16T13:36:38Z					biological_process											owl:Class	
GO:0046589	biolink:NamedThing	ribonuclease T1 activity	Catalysis of the endonucleolytic cleavage to nucleoside 3'-phosphates and 3'-phosphooligonucleotides ending in Gp with 2',3'-cyclic phosphate intermediates.	tmpzr1t_l9r_go_relaxed.owl	ribonuclease N1|binase activity|RNase G|ribonuclease U1|ribonuclease Ch|RNase F1|guanyloribonuclease activity|ribonuclease SA|RNase N1 activity|Aspergillus oryzae ribonuclease activity|RNase N2 activity|RNase Sa|RNase T1 activity|ribonuclease N3|RNase T1|ribonuclease PP1|guanyl-specific RNase activity|ribonuclease guaninenucleotido-2'-transferase (cyclizing)|ribonuclease C2|ribonuclease F1				MetaCyc:3.1.27.3-RXN|EC:4.6.1.24									molecular_function											owl:Class	
GO:0006086	biolink:NamedThing	acetyl-CoA biosynthetic process from pyruvate	The chemical reactions and pathways resulting in the formation of acetyl-CoA from pyruvate.	tmpzr1t_l9r_go_relaxed.owl	acetyl-CoA formation from pyruvate|pyruvate dehydrogenase pathway|acetyl-CoA anabolism from pyruvate|acetyl-CoA synthesis from pyruvate				MetaCyc:PYRUVDEHYD-PWY									biological_process											owl:Class	
GO:0043857	biolink:NamedThing	N-acetylornithine carbamoyltransferase activity	Catalysis of the reaction: N(2)-acetyl-L-ornithine + carbamoyl phosphate = N(2)-acetyl-L-citrulline + H(+) + phosphate.	tmpzr1t_l9r_go_relaxed.owl	carbamoyl-phosphate:2-N-acetyl-L-ornithine carbamoyltransferase activity|carbamoyl-phosphate:N2-acetyl-L-ornithine carbamoyltransferase activity|acetylornithine transcarbamylase activity|N-acetylornithine transcarbamylase activity|AOTC				RHEA:18609|KEGG_REACTION:R07245|EC:2.1.3.9|MetaCyc:2.1.3.9-RXN									molecular_function											owl:Class	
GO:0046725	biolink:NamedThing	negative regulation by virus of viral protein levels in host cell	Any process where the infecting virus reduces the levels of viral proteins in a cell.	tmpzr1t_l9r_go_relaxed.owl	inhibition of viral protein levels in host cell|negative regulation of viral protein levels|downregulation of viral protein levels in host cell|down-regulation of viral protein levels in host cell|down regulation of viral protein levels in host cell													biological_process											owl:Class	
GO:0103084	biolink:NamedThing	methylthiobutylmalate dehydrogenase activity	Catalysis of the reaction: 3-(4'-methylthio)butylmalate <=> H+ + 2-oxo-7-methylthioheptanoate + carbon dioxide.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXNQT-4168									molecular_function											owl:Class	
GO:0021624	biolink:NamedThing	oculomotor nerve structural organization	The process that contributes to the act of creating the structural organization of the oculomotor nerve. This process pertains to the physical shaping of a rudimentary structure. This motor nerve innervates all extraocular muscles except the superior oblique and the lateral rectus muscles. The superior division supplies the levator palpebrae superioris and superior rectus muscles. The inferior division supplies the medial rectus, inferior rectus and inferior oblique muscles. This nerve also innervates the striated muscles of the eyelid. Pupillary constriction and lens movement are mediated by this nerve for near vision. In the orbit the inferior division sends branches that enter the ciliary ganglion where they form functional contacts (synapses) with the ganglion cells. The ganglion cells send nerve fibers into the back of the eye where they travel to ultimately innervate the ciliary muscle and the constrictor pupillae muscle.	tmpzr1t_l9r_go_relaxed.owl	CN III structural organization|oculomotor nerve structural organisation													biological_process											owl:Class	
GO:0051469	biolink:NamedThing	vesicle fusion with vacuole	The joining of the lipid bilayer membrane around a vesicle with the lipid bilayer membrane around the vacuole.	tmpzr1t_l9r_go_relaxed.owl	heterotypic vacuole fusion, non-autophagic|heterotypic vacuole fusion (non-autophagic)											GO:0042146		biological_process											owl:Class	
GO:1903842	biolink:NamedThing	response to arsenite ion	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an arsenite ion stimulus.	tmpzr1t_l9r_go_relaxed.owl								mr	2015-01-22T19:56:05Z					biological_process											owl:Class	
GO:0018299	biolink:NamedThing	iron incorporation into the Rieske iron-sulfur cluster via bis-L-cysteinyl bis-L-histidino diiron disulfide	The incorporation of iron into a Rieske 4Fe-4S iron-sulfur cluster via bis-L-cysteinyl bis-L-histidino diiron disulfide.	tmpzr1t_l9r_go_relaxed.owl	iron incorporation into the Rieske iron-sulphur cluster via bis-L-cysteinyl bis-L-histidino diiron disulphide				RESID:AA0225									biological_process											owl:Class	
GO:0030043	biolink:NamedThing	actin filament fragmentation	The severing of actin filaments into numerous short fragments, usually mediated by actin severing proteins.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0072162	biolink:NamedThing	metanephric mesenchymal cell differentiation	The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesenchymal cells of the metanephros as it progresses from its formation to the mature state.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-02-26T01:35:00Z					biological_process											owl:Class	
GO:0033286	biolink:NamedThing	ATPase-coupled ectoine transmembrane transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + ectoine(out/in) = ADP + phosphate + ectoine(in/out).	tmpzr1t_l9r_go_relaxed.owl	ectoine transmembrane transporter activity|ATP-dependent ectoine transmembrane transporter activity|ectoine-transporting ATPase activity				RHEA:32787							GO:0051471		molecular_function											owl:Class	
GO:0061873	biolink:NamedThing	regulation of hepatic stellate cell contraction	Any process that modulates the frequency, rate or extent of hepatic stellate cell contraction.	tmpzr1t_l9r_go_relaxed.owl								dph	2017-05-01T13:26:49Z					biological_process											owl:Class	
GO:0033780	biolink:NamedThing	taurochenodeoxycholate 6alpha-hydroxylase activity	Catalysis of the reactions: taurochenodeoxycholate + NADPH + H+ + O2 = taurohyocholate + NADP+ + H2O, and lithocholate + NADPH + H+ + O2 = hyodeoxycholate + NADP+ + H2O.	tmpzr1t_l9r_go_relaxed.owl	CYP3A4|taurochenodeoxycholate 6alpha-monooxygenase activity|CYP4A21|taurochenodeoxycholate,NADPH:oxygen oxidoreductase (6alpha-hydroxylating) activity				MetaCyc:RXN-7977|EC:1.14.13.97|RHEA:23644									molecular_function											owl:Class	
GO:1904674	biolink:NamedThing	positive regulation of somatic stem cell population maintenance	Any process that activates or increases the frequency, rate or extent of somatic stem cell population maintenance.	tmpzr1t_l9r_go_relaxed.owl	up regulation of somatic stem cell population maintenance|up-regulation of somatic stem cell population maintenance|activation of somatic stem cell population maintenance|upregulation of somatic stem cell population maintenance							rph	2015-09-14T08:40:32Z					biological_process											owl:Class	
GO:0044323	biolink:NamedThing	retinoic acid-responsive element binding	Binding to a retinoic acid-responsive element, a variable direct repeat of the sequence PuGGTCA spaced by five nucleotides (DR5) found in the promoters of retinoic acid-responsive genes, to which retinoic acid receptors bind.	tmpzr1t_l9r_go_relaxed.owl	RARE binding					Note that as agreed during the transcription overhaul, terms specifying binding to specific transcription regulatory motifs are no longer being created. The level of specificity GO has decided to go to is the "core promoter", "core promoter proximal region" and "enhancer". To capture more detail, please consider using column 16.		jl	2010-08-03T03:19:05Z					molecular_function											owl:Class	
GO:0140643	biolink:NamedThing	hydroxymethylglutaryl-CoA reductase (NADH) activity	Catalysis of the reaction: (R)-mevalonate + CoA + 2 NAD(+) <=> 3-hydroxy-3-methylglutaryl-CoA + 2 NADH.	tmpzr1t_l9r_go_relaxed.owl	beta-hydroxy-beta-methylglutaryl CoA-reductase activity|hydroxymethylglutaryl coenzyme A reductase activity|3-hydroxy-3-methylglutaryl coenzyme A reductase activity|HMG-CoA reductase activity|beta-hydroxy-beta-methylglutaryl coenzyme A reductase activity	https://github.com/geneontology/go-ontology/issues/21411			RHEA:14833|EC:1.1.1.88|MetaCyc:HYDROXYMETHYLGLUTARYL-COA-REDUCTASE-RXN|KEGG_REACTION:R02081	Note that this activity is not present in eukaryotes, see PMID:29224355.		pg	2021-05-11T16:00:35Z					molecular_function											owl:Class	
GO:0000244	biolink:NamedThing	spliceosomal tri-snRNP complex assembly	The formation of a tri-snRNP complex containing U4 and U6 (or U4atac and U6atac) snRNAs and U5 snRNAs and associated proteins. This includes reannealing of U4 and U6 (or U4atac and U6atac) snRNAs released from previous rounds of splicing to reform the U4/U6 snRNP (or U4atac/U6atac snRNP) as well as the subsequent association of the U5 snRNP with the U4/U6 snRNP (or U4atac/U6atac snRNP) to form a tri-snRNP that is ready to reassemble into another spliceosome complex.	tmpzr1t_l9r_go_relaxed.owl	spliceosomal tri-snRNP assembly|spliceosomal tri-snRNP U4/U6.U5 assembly|assembly of spliceosomal tri-snRNP|spliceosomal tri-snRNP U4atac/U6atac.U5 assembly|snRNP recycling|assembly of spliceosomal tri-snRNP U4/U6.U5|assembly of spliceosomal tri-snRNP U4atac/U6atac.U5											GO:0000351|GO:0000355		biological_process											owl:Class	
GO:0072179	biolink:NamedThing	nephric duct formation	The developmental process pertaining to the initial formation of a nephric duct. A nephric duct is a tube that drains a primitive kidney.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-02-26T02:35:55Z					biological_process											owl:Class	
GO:2000887	biolink:NamedThing	glucuronoarabinoxylan catabolic process	The chemical reactions and pathways resulting in the breakdown of a glucuronoarabinoxylan.	tmpzr1t_l9r_go_relaxed.owl	glucuronoarabinoxylan catabolism							jl	2011-07-28T09:39:26Z					biological_process											owl:Class	
GO:0007096	biolink:NamedThing	regulation of exit from mitosis	Any process involved in the progression from anaphase/telophase to G1 that is associated with a conversion from high to low mitotic CDK activity.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0036050	biolink:NamedThing	peptidyl-lysine succinylation	The modification of a peptidyl-lysine residue by the addition of a succinyl group (CO-CH2-CH2-CO) to form N6-succinyl-L-lysine.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0545			bf	2011-12-12T09:51:27Z					biological_process											owl:Class	
GO:0070404	biolink:NamedThing	NADH binding	Binding to the reduced form, NADH, of nicotinamide adenine dinucleotide, a coenzyme involved in many redox and biosynthetic reactions.	tmpzr1t_l9r_go_relaxed.owl	reduced nicotinamide adenine dinucleotide binding|NAD (reduced) binding|reduced NAD binding													molecular_function											owl:Class	
GO:0072587	biolink:NamedThing	DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activator activity	Binds to and increases the activity of ATP-hydrolyzing DNA topoisomerase. DNA topoisomerase (ATP-hydrolyzing) regulator activity catalyzes a DNA topological transformation by transiently cleaving a pair of complementary DNA strands to form a gate through which a second double-stranded DNA segment is passed, after which the severed strands in the first DNA segment are rejoined; product release is coupled to ATP binding and hydrolysis; changes the linking number in multiples of 2.	tmpzr1t_l9r_go_relaxed.owl								mah	2011-02-09T05:34:47Z					molecular_function											owl:Class	
GO:0090069	biolink:NamedThing	regulation of ribosome biogenesis	Any process that modulates the rate, frequency or extent of ribosome biogenesis. Ribosome biogenesis is the cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-09-11T10:32:17Z					biological_process											owl:Class	
GO:0070642	biolink:NamedThing	vitamin D5 metabolic process	The chemical reactions and pathways involving vitamin D5, (1S,3Z)-3-[(2E)-2-[(1R,3aS,7aR)-1-[(1R,4S)-4-ethyl-1,5-dimethylhexyl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylene-1-cyclohexanol.	tmpzr1t_l9r_go_relaxed.owl	vitamin D5 metabolism							mah	2009-05-08T02:47:41Z					biological_process											owl:Class	
GO:0072736	biolink:NamedThing	cellular response to tert-butyl hydroperoxide	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tert-butyl hydroperoxide (t-BOOH) stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to 2-methyl-prop-2-yl-hydroperoxide|cellular response to t-BOOH							mah	2012-07-17T10:33:00Z					biological_process											owl:Class	
GO:0072735	biolink:NamedThing	response to tert-butyl hydroperoxide	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tert-butyl hydroperoxide (t-BOOH) stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to t-BOOH|response to 2-methyl-prop-2-yl-hydroperoxide							mah	2012-07-17T10:33:00Z					biological_process											owl:Class	
GO:0080107	biolink:NamedThing	8-methylthiopropyl glucosinolate S-oxygenase activity	Catalysis of the reaction: 8-methylthiopropyl-glucosinolate = 8-methylsulfinylpropyl-glucosinolate.	tmpzr1t_l9r_go_relaxed.owl								dhl	2009-04-23T04:30:08Z					molecular_function											owl:Class	
GO:1905346	biolink:NamedThing	protein localization to cleavage furrow rim	A process in which a protein is transported to, or maintained in, a location within a cleavage furrow rim.	tmpzr1t_l9r_go_relaxed.owl	protein localization in cleavage furrow rim|protein localisation in cleavage furrow rim|protein localisation to cleavage furrow rim							mah	2016-08-01T13:20:13Z					biological_process											owl:Class	
GO:1905345	biolink:NamedThing	protein localization to cleavage furrow	A process in which a protein is transported to, or maintained in, a location within a cleavage furrow.	tmpzr1t_l9r_go_relaxed.owl	protein localisation in cleavage furrow|protein localisation to cleavage furrow|protein localization in cleavage furrow							mah	2016-08-01T13:20:05Z					biological_process											owl:Class	
GO:0031833	biolink:NamedThing	type 7 serotonin receptor binding	Binding to a type 7 serotonin receptor.	tmpzr1t_l9r_go_relaxed.owl	5-hydroxytryptamine 7 receptor binding|type 7 serotonin receptor ligand													molecular_function											owl:Class	
GO:0008761	biolink:NamedThing	UDP-N-acetylglucosamine 2-epimerase activity	Catalysis of the reaction: UDP-N-acetyl-D-glucosamine = UDP-N-acetyl-D-mannosamine.	tmpzr1t_l9r_go_relaxed.owl	UDP-GlcNAc-2-epimerase activity|UDP-N-acetylglucosamine 2'-epimerase activity|uridine diphospho-N-acetylglucosamine 2'-epimerase activity|UDP-N-acetyl-D-glucosamine 2-epimerase activity|uridine diphosphoacetylglucosamine 2'-epimerase activity|uridine diphosphate-N-acetylglucosamine-2'-epimerase activity				RHEA:17213|Reactome:R-HSA-4088338|EC:5.1.3.14|Reactome:R-HSA-4085021|MetaCyc:UDPGLCNACEPIM-RXN									molecular_function											owl:Class	
GO:0016118	biolink:NamedThing	carotenoid catabolic process	The chemical reactions and pathways resulting in the breakdown of carotenoids, tetraterpenoid compounds in which two units of 4 isoprenoid residues joined head-to-tail are themselves joined tail-to-tail.	tmpzr1t_l9r_go_relaxed.owl	carotenoid degradation|carotenoid breakdown|carotenoid catabolism													biological_process											owl:Class	
GO:0036027	biolink:NamedThing	protein C inhibitor-PLAU complex	A heterodimeric protein complex that contains protein C inhibitor (SERPINA5) and urokinase-type plasminogen activator (PLAU); formation of the complex inhibits the serine protease activity of urokinase-type plasminogen activator.	tmpzr1t_l9r_go_relaxed.owl	protein C inhibitor-uPA complex|protein C inhibitor-urokinase-type plasminogen activator complex|SERPINA5-PLAU complex|serpin A5-PLAU complex|PCI-PLAU complex|plasma serine protease inhibitor-PLAU complex|protein C inhibitor-U-plasminogen activator complex							bf	2011-10-19T01:37:03Z					cellular_component											owl:Class	
GO:0050480	biolink:NamedThing	imidazolonepropionase activity	Catalysis of the reaction: (S)-3-(4-oxo-4,5-dihydro-1H-imidazol-5-yl)propanoic acid + H(2)O = N-formimidoyl-L-glutamate + H(+).	tmpzr1t_l9r_go_relaxed.owl	imidazolone propionic acid hydrolase activity|imidazolone-5-propionate hydrolase activity|4(5)-imidazolone-5(4)-propionic acid hydrolase activity|3-(5-oxo-4,5-dihydro-3H-imidazol-4-yl)propanoate amidohydrolase activity				EC:3.5.2.7|MetaCyc:IMIDAZOLONEPROPIONASE-RXN|KEGG_REACTION:R02288|RHEA:23660									molecular_function											owl:Class	
GO:0042736	biolink:NamedThing	NADH kinase activity	Catalysis of the reaction: ATP + NADH = ADP + 2 H(+) + NADPH.	tmpzr1t_l9r_go_relaxed.owl	ATP:NADH 2'-phosphotransferase activity|reduced diphosphopyridine nucleotide kinase activity|reduced nicotinamide adenine dinucleotide kinase (phosphorylating)|DPNH kinase activity				EC:2.7.1.86|RHEA:12260|KEGG_REACTION:R00105|MetaCyc:NADH-KINASE-RXN									molecular_function											owl:Class	
GO:0048906	biolink:NamedThing	anterior lateral line neuromast support cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of an anterior lateral line neuromast support cell. Support cells are non-sensory cells of the neuromast that extend between the sensory hair cells from the basement membrane to the apical surface; they are surrounded by mantle cells.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0140358	biolink:NamedThing	P-type transmembrane transporter activity	Primary active transporter that auto-phosphorylates (hence P) at a key conserved aspartate residue, generating a conformational change that allows transport of the substrate. Hydrolysis of the phosphorylated Asp residue, catalyzed by the actuator (A) domain, results in another state with occluded substrates. Upon dissociation of Mg2+ and inorganic phosphate (Pi), the enzyme reverts to the initial state, in which the counter-transported substrate is released into the cytosol.	tmpzr1t_l9r_go_relaxed.owl	P-type ATPase|E1-E2 ATPase	https://github.com/geneontology/go-ontology/issues/21273|https://github.com/geneontology/go-ontology/issues/20529			TC:3.A.3|Wikipedia:P-type_ATPase			pg	2019-06-25T19:07:46Z					molecular_function											owl:Class	
GO:0102140	biolink:NamedThing	heparan sulfate N-deacetylase activity	Catalysis of the reaction: H2O + [heparan sulfate]-N-acetyl-alpha-D-glucosamine = acetate + H+ + [heparan sulfate]-alpha-D-glucosamine.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-11557									molecular_function											owl:Class	
GO:1902046	biolink:NamedThing	positive regulation of Fas signaling pathway	Any process that activates or increases the frequency, rate or extent of Fas signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	activation of Fas receptor signaling pathway|positive regulation of Fas-FasL signaling pathway|up-regulation of FasR signaling pathway|up-regulation of CD95 signaling pathway|activation of Apo-1 signaling pathway|positive regulation of Apo-1 signaling pathway|activation of CD95 signaling pathway|upregulation of Fas-FasL signaling pathway|up regulation of Apo-1 signaling pathway|positive regulation of Fas receptor signaling pathway|up-regulation of FAS ligand-Fas signaling pathway|positive regulation of CD95 signaling pathway|activation of FasL signaling pathway|upregulation of Fas receptor signaling pathway|up-regulation of FasL signaling pathway|up regulation of Fas-FasL signaling pathway|up regulation of Fas signaling pathway|up-regulation of Fas receptor signaling pathway|upregulation of Fas signaling pathway|up-regulation of Fas signaling pathway|activation of Fas-FasL signaling pathway|upregulation of Apo-1 signaling pathway|upregulation of FasL signaling pathway|upregulation of FAS ligand-Fas signaling pathway|activation of FAS ligand-Fas signaling pathway|up regulation of FasL signaling pathway|up regulation of Fas receptor signaling pathway|up-regulation of Apo-1 signaling pathway|up regulation of FAS ligand-Fas signaling pathway|up regulation of CD95 signaling pathway|activation of FasR signaling pathway|up regulation of FasR signaling pathway|activation of Fas signaling pathway|positive regulation of FasL signaling pathway|positive regulation of FasR signaling pathway|up-regulation of Fas-FasL signaling pathway|upregulation of FasR signaling pathway|upregulation of CD95 signaling pathway|positive regulation of FAS ligand-Fas signaling pathway							lb	2013-04-03T07:21:33Z					biological_process											owl:Class	
GO:0018043	biolink:NamedThing	C-terminal peptidyl-isoleucine amidation	The formation of a C-terminal peptidyl-isoleucine amide by hydrolysis and oxidation of an interior Ile-Gly peptide in a secreted protein.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0090									biological_process											owl:Class	
GO:0030266	biolink:NamedThing	quinate 3-dehydrogenase (NAD+) activity	Catalysis of the reaction: (-)-quinate + NAD+ = (-)-3-dehydroquinate + NADH + H+.	tmpzr1t_l9r_go_relaxed.owl	quinate:NAD(+) 5-oxidoreductase activity|quinic dehydrogenase activity|quinate:NAD 3-oxidoreductase activity|quinate:NAD 5-oxidoreductase activity|quinate:NAD(+) 3-oxidoreductase activity				MetaCyc:QUINATE-5-DEHYDROGENASE-RXN|RHEA:22364|EC:1.1.1.24|EC:1.1.1.282|KEGG_REACTION:R01872									molecular_function											owl:Class	
GO:0015160	biolink:NamedThing	beta-glucan transmembrane transporter activity	Enables the transfer of beta-glucans from one side of a membrane to the other. Beta-glucans are compounds composed of glucose residues linked by beta-glucosidic bonds.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0016243	biolink:NamedThing	regulation of autophagosome size	Any process that modulates the size of the autophagosome.	tmpzr1t_l9r_go_relaxed.owl	regulation of autophagic vacuole size													biological_process											owl:Class	
GO:0010622	biolink:NamedThing	specification of ovule identity	The regionalization process in which the identity of an ovule is specified. Identity is considered to be the aggregate of characteristics by which a structure is recognized.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0005547	biolink:NamedThing	phosphatidylinositol-3,4,5-trisphosphate binding	Binding to phosphatidylinositol-3,4,5-trisphosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 3', 4' and 5' positions.	tmpzr1t_l9r_go_relaxed.owl	PIP3 binding													molecular_function											owl:Class	
GO:0018555	biolink:NamedThing	phenanthrene dioxygenase activity	Catalysis of the reaction: phenanthrene + NADH + H+ + O2 = NAD+ + cis-3,4-dihydroxy-3,4-dihydrophenanthrene.	tmpzr1t_l9r_go_relaxed.owl					EC:1.13.11.-|UM-BBD_reactionID:r0455									molecular_function											owl:Class	
GO:0042765	biolink:NamedThing	GPI-anchor transamidase complex	An enzyme complex which in humans and yeast consists of at least five proteins; for example, the complex contains GAA1, GPI8, PIG-S, PIG-U, and PIG-T in human, and Gaa1p, Gab1p, Gpi8p, Gpi16p, and Gpi17p in yeast. Catalyzes the posttranslational attachment of the carboxy-terminus of a precursor protein to a GPI-anchor.	tmpzr1t_l9r_go_relaxed.owl	GPIT complex					Note that this term should not be confused with 'glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex ; GO:0000506', which represents a distinct complex with a different catalytic activity.								cellular_component											owl:Class	
GO:0033694	biolink:NamedThing	oxidoreductase activity, acting on the CH-NH group of donors, iron-sulfur protein as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH group acts as a hydrogen or electron donor and reduces an iron-sulfur protein.	tmpzr1t_l9r_go_relaxed.owl					EC:1.5.7.-									molecular_function											owl:Class	
GO:1900063	biolink:NamedThing	regulation of peroxisome organization	Any process that modulates the frequency, rate or extent of peroxisome organization.	tmpzr1t_l9r_go_relaxed.owl	regulation of peroxisome organisation|regulation of peroxisome-assembly ATPase activity|regulation of peroxisome organization and biogenesis							dph	2012-01-26T01:49:05Z					biological_process											owl:Class	
GO:0018252	biolink:NamedThing	peptide cross-linking via L-seryl-5-imidazolinone glycine	The formation of the green fluorescent protein chromophore cross-link from the alpha-carboxyl carbon of residue n, a serine, to the alpha-amino nitrogen of residue n+2, a glycine, and a dehydration to form a double bond to the alpha-amino nitrogen of residue n+1. This cross-linking is coupled with a dehydrogenation of residue n+1 to form a double bond between the alpha and beta carbons.	tmpzr1t_l9r_go_relaxed.owl	biosynthesis of protein-protein cross-link via L-seryl-5-imidazolinone glycine|biosynthetic process of protein-protein cross-link via L-seryl-5-imidazolinone glycine				RESID:AA0184	See also the biological process term 'peptidyl-tyrosine dehydrogenation ; GO:0018251'.								biological_process											owl:Class	
GO:0099052	biolink:NamedThing	vesicle scission involved in clathrin-mediated endocytosis	The membrane scission process that is the final step in the formation of a clathrin-coated endocytic vesicle: separation from the plasma membrane.	tmpzr1t_l9r_go_relaxed.owl						Like other vesicle scission events this involves dynamin. At least some of the dynamin recruiting factors are distinct to scission of clathrin-coated vesicles (PMID:21779028).								biological_process											owl:Class	
GO:0034431	biolink:NamedThing	bis(5'-adenosyl)-hexaphosphatase activity	Catalysis of the reaction: P1-P6-bis(5'-adenosyl) hexaphosphate + H2O = AMP + adenosine 5'-pentaphosphate.	tmpzr1t_l9r_go_relaxed.owl	AP6A hydrolase activity|AP(6)A hydrolase activity|diadenosine 5',5'''-P1,P6-hexaphosphate hydrolase activity|AP-6-A hydrolase activity				RHEA:32047									molecular_function											owl:Class	
GO:0002397	biolink:NamedThing	MHC class I protein complex assembly	The aggregation, arrangement and bonding together of a set of components to form an MHC class I protein complex. Class I here refers to classical class I molecules.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0015131	biolink:NamedThing	oxaloacetate transmembrane transporter activity	Enables the transfer of oxaloacetate, the anion of oxobutanedioic acid, from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1905381	biolink:NamedThing	negative regulation of snRNA transcription by RNA polymerase II	Any process that stops, prevents or reduces the frequency, rate or extent of snRNA transcription mediated by RNA polymerase II.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of snRNA transcription from RNA polymerase II promoter|downregulation of snRNA transcription from Pol II promoter|down-regulation of snRNA transcription from RNA polymerase II promoter|down-regulation of snRNA transcription from Pol II promoter|negative regulation of snRNA transcription from Pol II promoter|inhibition of snRNA transcription from RNA polymerase II promoter|downregulation of snRNA transcription from RNA polymerase II promoter|inhibition of snRNA transcription from Pol II promoter|down regulation of snRNA transcription from RNA polymerase II promoter|down regulation of snRNA transcription from Pol II promoter							bhm	2016-08-18T13:39:27Z					biological_process											owl:Class	
GO:0032723	biolink:NamedThing	positive regulation of connective tissue growth factor production	Any process that activates or increases the frequency, rate, or extent of connective tissue growth factor production.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of Hcs24 production|activation of connective tissue growth factor production|positive regulation of Fisp12 production|positive regulation of CTGF production|positive regulation of CCN2 production|positive regulation of hypertrophic chondrocyte-specific gene product 24 production|up-regulation of connective tissue growth factor production|positive regulation of connective tissue growth factor biosynthetic process|upregulation of connective tissue growth factor production|positive regulation of IGFBP8 production|up regulation of connective tissue growth factor production|stimulation of connective tissue growth factor production											GO:0045422		biological_process											owl:Class	
GO:0032643	biolink:NamedThing	regulation of connective tissue growth factor production	Any process that modulates the frequency, rate, or extent of connective tissue growth factor production.	tmpzr1t_l9r_go_relaxed.owl	regulation of connective tissue growth factor biosynthetic process|regulation of CCN2 production|regulation of Fisp12 production|regulation of CTGF production|regulation of IGFBP8 production|regulation of Hcs24 production|regulation of hypertrophic chondrocyte-specific gene product 24 production											GO:0045420		biological_process											owl:Class	
GO:0009404	biolink:NamedThing	toxin metabolic process	The chemical reactions and pathways involving a toxin, a poisonous compound (typically a protein) that is produced by cells or organisms and that can cause disease when introduced into the body or tissues of an organism.	tmpzr1t_l9r_go_relaxed.owl	toxin metabolism													biological_process											owl:Class	
GO:0050021	biolink:NamedThing	L-arabinonolactonase activity	Catalysis of the reaction: L-arabinono-1,4-lactone + H(2)O = L-arabinonate + H(+).	tmpzr1t_l9r_go_relaxed.owl	L-arabinono-1,4-lactone lactonohydrolase activity				MetaCyc:L-ARABINONOLACTONASE-RXN|EC:3.1.1.15|KEGG_REACTION:R02526|RHEA:16217									molecular_function											owl:Class	
GO:0072059	biolink:NamedThing	cortical collecting duct development	The process whose specific outcome is the progression of the cortical collecting duct over time, from its formation to the mature structure. The cortical collecting duct is the portion of the collecting duct that resides in the renal cortex.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-01-25T04:07:07Z					biological_process											owl:Class	
GO:0002497	biolink:NamedThing	proteasomal proteolysis associated with antigen processing and presentation	The hydrolysis of a peptide bond or bonds within a protein by the proteasome complex contributing to antigen processing and presentation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0034930	biolink:NamedThing	1-hydroxypyrene sulfotransferase activity	Catalysis of the reaction: 1-hydroxypyrene + XSO3- = 1-pyrenylsulfate + HX.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0952									molecular_function											owl:Class	
GO:0034692	biolink:NamedThing	E.F.G complex	A protein complex that comprises three core spliceosomal proteins, designated E, F, and G. Formation of the E.F.G complex is essential but not sufficient for the formation of a stable U1 snRNP complex.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0004039	biolink:NamedThing	allophanate hydrolase activity	Catalysis of the reaction: H(2)O + 3 H(+) + urea-1-carboxylate = 2 CO(2) + 2 NH(4)(+).	tmpzr1t_l9r_go_relaxed.owl	allophanate lyase activity|urea-1-carboxylate amidohydrolase activity				UM-BBD_reactionID:r0848|MetaCyc:ALLOPHANATE-HYDROLASE-RXN|RHEA:19029|EC:3.5.1.54|KEGG_REACTION:R00005									molecular_function											owl:Class	
GO:0150163	biolink:NamedThing	miRNA-mediated activation of transcription by RNA polymerase II	Any process mediated by a microRNA (miRNA) that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.	tmpzr1t_l9r_go_relaxed.owl								bc	2020-01-14T12:08:14Z					biological_process											owl:Class	
GO:0002897	biolink:NamedThing	positive regulation of central B cell tolerance induction	Any process that activates or increases the frequency, rate, or extent of central B cell tolerance induction.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of central B cell tolerance induction|upregulation of central B cell tolerance induction|stimulation of central B cell tolerance induction|up regulation of central B cell tolerance induction|activation of central B cell tolerance induction													biological_process											owl:Class	
GO:0097036	biolink:NamedThing	regulation of plasma membrane sterol distribution	Any process that modulates the proportions or spatial arrangement of sterols in the plasma membrane.	tmpzr1t_l9r_go_relaxed.owl								pr	2011-04-08T02:08:08Z					biological_process											owl:Class	
GO:0002203	biolink:NamedThing	proteolysis by cytosolic proteases associated with antigen processing and presentation	The hydrolysis of a peptide bond or bonds within a protein by cytosolic resident proteases during antigen processing and presentation.	tmpzr1t_l9r_go_relaxed.owl						Note that a separate term covers proteolysis by the proteasome complex (proteasomal proteolysis associated with antigen processing and presentation ; GO:0002497).								biological_process											owl:Class	
GO:0045517	biolink:NamedThing	interleukin-20 receptor binding	Binding to an interleukin-20 receptor.	tmpzr1t_l9r_go_relaxed.owl	IL-20|interleukin-20 receptor ligand													molecular_function											owl:Class	
GO:0004503	biolink:NamedThing	tyrosinase activity	Catalysis of the reaction: L-tyrosine + O2 = L-DOPAquinone + H2O. This reaction can use both monophenols (such as tyrosine) and catechols (o-diphenols) as substrates.	tmpzr1t_l9r_go_relaxed.owl	monophenol monooxygenase activity|phenol oxidase activity|phenolase activity|N-acetyl-6-hydroxytryptophan oxidase activity|o-diphenol:O2 oxidoreductase activity|cresolase activity|catecholase|chlorogenic acid oxidase activity|monophenol oxidase activity|pyrocatechol oxidase|dopa oxidase|chlorogenic oxidase activity|o-diphenol oxidoreductase|monophenol monooxidase activity|prophenol oxidase activity|L-tyrosine monooxygenase activity|tyrosine-dopa oxidase activity|monophenol oxygenase|monophenolase activity|prophenoloxidase activity|o-diphenol oxidase activity	https://github.com/geneontology/go-ontology/issues/21024#issuecomment-909025243			MetaCyc:MONOPHENOL-MONOOXYGENASE-RXN|EC:1.14.18.1	In mammals, L-DOPA can act as a cofactor for the catalyzed reaction; therefore in some resources L-DOPA is shown on both sides of the reaction. GO:0004503 describes the monooxygenation of the monophenol, L-tyrosine. For oxidation of diphenols (including L-DOPA and dopamine), consider instead the term 'catechol oxidase activity ; GO:0004097' and its children.								molecular_function											owl:Class	
GO:0071957	biolink:NamedThing	old mitotic spindle pole body	The spindle pole body that exists in a cell prior to spindle pole body duplication. An old spindle pole body segregates to the daughter cell upon mitosis, and lacks active proteins involved in signaling exit from mitosis.	tmpzr1t_l9r_go_relaxed.owl	old SPB							mah	2011-06-01T02:32:10Z					cellular_component											owl:Class	
GO:0047601	biolink:NamedThing	acetate kinase (diphosphate) activity	Catalysis of the reaction: acetate + diphosphate = acetyl phosphate + phosphate.	tmpzr1t_l9r_go_relaxed.owl	acetate kinase (pyrophosphate) activity|diphosphate:acetate phosphotransferase activity|pyrophosphate-acetate phosphotransferase activity				KEGG_REACTION:R00320|RHEA:24276|MetaCyc:ACETATE-KINASE-PYROPHOSPHATE-RXN|EC:2.7.2.12									molecular_function											owl:Class	
GO:0033802	biolink:NamedThing	isoliquiritigenin 2'-O-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + isoliquiritigenin = 2'-O-methylisoliquiritigenin + S-adenosyl-L-homocysteine + H(+).	tmpzr1t_l9r_go_relaxed.owl	S-adenosyl-L-methionine:isoliquiritigenin 2'-O-methyltransferase activity|CHMT|chalcone OMT				EC:2.1.1.154|MetaCyc:RXN-3501|KEGG_REACTION:R07242|RHEA:21608									molecular_function											owl:Class	
GO:0001945	biolink:NamedThing	lymph vessel development	The process whose specific outcome is the progression of a lymph vessel over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0006254	biolink:NamedThing	CTP catabolic process	The chemical reactions and pathways resulting in the breakdown of CTP, cytidine 5'-triphosphate.	tmpzr1t_l9r_go_relaxed.owl	CTP catabolism|CTP hydrolysis|CTP breakdown|CTP degradation													biological_process											owl:Class	
GO:0032728	biolink:NamedThing	positive regulation of interferon-beta production	Any process that activates or increases the frequency, rate, or extent of interferon-beta production.	tmpzr1t_l9r_go_relaxed.owl	stimulation of interferon-beta production|positive regulation of interferon-beta secretion|activation of interferon-beta production|positive regulation of interferon-beta biosynthetic process|upregulation of interferon-beta production|up-regulation of interferon-beta production|up regulation of interferon-beta production|positive regulation of IFN-beta production											GO:0045359|GO:0035549		biological_process											owl:Class	
GO:0120289	biolink:NamedThing	positive regulation of aspartic endopeptidase activity, intramembrane cleaving	Any process that increases the frequency, rate or extent of intramembrane cleaving aspartic-type endopeptidase activity.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/20341						krc	2020-11-19T22:27:57Z					biological_process											owl:Class	
GO:0106162	biolink:NamedThing	mRNA N-acetyltransferase activity	Catalysis of the reaction: a cytidine in mRNA + acetyl-CoA + ATP + H2O = ADP + an N(4)-acetylcytidine in mRNA + CoA + H(+) + phosphate.	tmpzr1t_l9r_go_relaxed.owl					RHEA:58480			hjd	2018-12-18T19:19:06Z					molecular_function											owl:Class	
GO:0120174	biolink:NamedThing	stress-induced homeostatically regulated protein degradation pathway	A stress-inducible protein catabolic pathway that promotes protein quality control by accelerating the degradation of misfolded ER membrane and cytosolic proteins, as well as native proteins. The pathway starts with the activation, by stress, of the Nma111p/Ynm3p serine protease, which cleaves the stress-induced hydrophilin Roq1p, resulting in the generation of a Roq1p cleavage product that selectively interacts with Ubr1p, an E3 ubiquitin ligase. Interaction with the Ubr1p type-1 substrate binding site reprograms the substrate specificity of this ubiquitin ligase resulting in the selective proteasome-mediated degradation of misfolded and native proteins. The pathway ends with degradation of the protein by the cytoplasmic proteasome. Currently, NMA111, ROQ1, UBR1, RAD6, and CDC48 are considered to be involved in this quality control pathway.	tmpzr1t_l9r_go_relaxed.owl	SHRED pathway					Note, although the SHRED pathway may contain some components in common with ER-associated protein degradation (ERAD) pathways (GO:0036503), such as UBR1, RAD6 and CDC48, other ERAD components, such as HRD1 and DOA10 do not appear to be involved, and as such these pathways are currently considered to be distinct. ERAD pathways target misfolded ER lumenal proteins (ERAD-L), ER membrane proteins (ERAD-M) and ER proteins with misfolded cytosolic domains (ERAD-C) by recognizing aberrant proteins, retrotranslocating these substrates to the cytosol, followed by subsequent substrate ubiquitination and proteosome-mediated degradation. In contrast the SHRED pathway, although inducible by stress, targets diverse ER membrane and cytosolic proteins as well as numerous other native proteins in the absence of stress. In the SHRED pathway an Nma111p serine protease-mediated cleavage results in the generation of a Roq1p fragment that then binds to the type-1 active site of Ubr1p, altering its substrate specificity, and leading to the proteasome-mediated degradation of both misfolded and native proteins. SHRED is also considered to be distinct from the endoplasmic reticulum unfolded protein response (GO:0030968), a process by which ER stress activates the ER membrane protein Ire1p, resulting in splicing of the HAC1 mRNA, followed by Hac1p-mediated up-regulation of UPR genes. Induction of SHRED does not require IRE1 or HAC1, and as such is currently considered to be distinct.		krc	2018-06-07T16:16:43Z					biological_process											owl:Class	
GO:0090532	biolink:NamedThing	L-ascorbic acid biosynthetic process via UDP-alpha-D-glucuronate	The chemical reactions and pathways resulting in the formation of L-ascorbic acid via the intermediate UDP-alpha-D-glucuronate.	tmpzr1t_l9r_go_relaxed.owl	L-ascorbic acid biosynthesis via UDP-alpha-D-glucuronate					This pathway occurs in most vertebrates, although not in guinea pigs and primates, including humans.		tb	2013-02-06T15:31:01Z					biological_process											owl:Class	
GO:1990948	biolink:NamedThing	ubiquitin ligase inhibitor activity	Binds to and stops, prevents or reduces the activity of a ubiquitin ligase.	tmpzr1t_l9r_go_relaxed.owl	mitotic anaphase-promoting complex inhibitor activity|APC-Cdc20 complex inhibitor activity							vw	2016-04-21T16:36:54Z			GO:0090645|GO:0061637		molecular_function											owl:Class	
GO:0015593	biolink:NamedThing	allose transmembrane transporter activity	Enables the transfer of allose from one side of a membrane to the other. Allose is an aldohexose similar to glucose, differing only in the configuration of the hydroxyl group of C-3.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0042208	biolink:NamedThing	propylene catabolic process	The chemical reactions and pathways resulting in the breakdown of propylene, an alkene produced by catalytic or thermal cracking of hydrocarbons or as a by-product of petroleum refining.	tmpzr1t_l9r_go_relaxed.owl	propylene degradation|propylene breakdown|propylene catabolism				UM-BBD_pathwayID:pro									biological_process											owl:Class	
GO:1902995	biolink:NamedThing	positive regulation of phospholipid efflux	Any process that activates or increases the frequency, rate or extent of phospholipid efflux.	tmpzr1t_l9r_go_relaxed.owl	up regulation of phospholipid export|activation of phospholipid export|activation of phospholipid efflux|positive regulation of phospholipid export|up-regulation of phospholipid efflux|upregulation of phospholipid export|up regulation of phospholipid efflux|up-regulation of phospholipid export|upregulation of phospholipid efflux							sjp	2014-05-08T14:55:22Z					biological_process											owl:Class	
GO:0097652	biolink:NamedThing	phosphatidylinositol 3-kinase complex, class II	A phosphatidylinositol 3-kinase complex that contains a catalytic subunit of a phosphatidylinositol 3-kinase (PI3K) enzyme and one or more adaptor proteins. There is no known obligatory regulatory subunit. The class II PI3K (PI3KC2) subfamily of genes has members in vertebrates, worm and fly, but none in yeast.	tmpzr1t_l9r_go_relaxed.owl	class II PI3K complex|class II phosphatidylinositol 3-kinase complex							pr	2014-09-16T13:14:17Z					cellular_component											owl:Class	
GO:1903171	biolink:NamedThing	carbon dioxide homeostasis	Any process involved in the maintenance of an internal steady state of carbon dioxide within an organism or cell.	tmpzr1t_l9r_go_relaxed.owl								mr	2014-07-11T20:58:24Z					biological_process											owl:Class	
GO:0006613	biolink:NamedThing	cotranslational protein targeting to membrane	The targeting of proteins to a membrane that occurs during translation. The transport of most secretory proteins, particularly those with more than 100 amino acids, into the endoplasmic reticulum lumen occurs in this manner, as does the import of some proteins into mitochondria.	tmpzr1t_l9r_go_relaxed.owl	cotranslational protein-membrane targeting|cotranslational membrane targeting|cotranslational protein membrane targeting													biological_process											owl:Class	
GO:0030095	biolink:NamedThing	chloroplast photosystem II	An integral chloroplast membrane complex containing the P680 reaction center. In the light, PSII functions as a water-plastoquinone oxidoreductase, transferring electrons from water to plastoquinone.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0060507	biolink:NamedThing	epidermal growth factor receptor signaling pathway involved in lung development	The series of molecular signals generated as a consequence of an epidermal growth factor-type receptor binding to one of its physiological ligands. This process contributes to lung development.	tmpzr1t_l9r_go_relaxed.owl	epidermal growth factor receptor signalling pathway involved in lung development													biological_process											owl:Class	
GO:0070391	biolink:NamedThing	response to lipoteichoic acid	Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipoteichoic acid stimulus; lipoteichoic acid is a major component of the cell wall of gram-positive bacteria and typically consists of a chain of glycerol-phosphate repeating units linked to a glycolipid anchor.	tmpzr1t_l9r_go_relaxed.owl	response to LTA													biological_process											owl:Class	
GO:0051008	biolink:NamedThing	Hsp27 protein binding	Binding to Hsp27 proteins, a lightweight heat shock protein.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0061590	biolink:NamedThing	calcium activated phosphatidylcholine scrambling	The movement of a population of phosphatidylcholine molecules from one leaflet of the plasma membrane bilayer to the opposite leaflet as a result of a calcium stimulus.	tmpzr1t_l9r_go_relaxed.owl								dph	2014-02-05T15:23:03Z					biological_process											owl:Class	
GO:0048842	biolink:NamedThing	positive regulation of axon extension involved in axon guidance	Any process that activates, maintains or increases the frequency, rate or extent of axon extension involved in axon guidance.	tmpzr1t_l9r_go_relaxed.owl	stimulation of axon extension involved in axon guidance|up regulation of axon extension involved in axon guidance|up-regulation of axon extension involved in axon guidance|upregulation of axon extension involved in axon guidance|activation of axon extension involved in axon guidance													biological_process											owl:Class	
GO:0102356	biolink:NamedThing	isoitalicene synthase activity	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate(3-) <=> diphosphoric acid + (+)-isoitalicene.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-13373									molecular_function											owl:Class	
GO:1903260	biolink:NamedThing	protein localization to mating projection tip	A process in which a protein is transported to, or maintained in, a location within a mating projection tip.	tmpzr1t_l9r_go_relaxed.owl	protein localization to shmoo tip|protein localization in mating projection tip|protein localisation to mating projection tip|protein localisation in mating projection tip|protein localization to conjugation tube tip							mah	2014-08-06T13:26:14Z					biological_process											owl:Class	
GO:0072051	biolink:NamedThing	juxtaglomerular apparatus development	The process whose specific outcome is the progression of the juxtaglomerular apparatus over time, from its formation to the mature structure. The juxtaglomerular apparatus is an anatomical structure that lies adjacent to the glomerulus and regulates kidney function.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-01-25T03:52:23Z					biological_process											owl:Class	
GO:1902108	biolink:NamedThing	regulation of mitochondrial membrane permeability involved in apoptotic process	Any regulation of mitochondrial membrane permeability that is involved in apoptotic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of mitochondrial membrane permeability involved in apoptotic program|regulation of transport across mitochondrial membrane involved in apoptosis|regulation of transport across mitochondrial membrane involved in type I programmed cell death|regulation of transport across mitochondrial membrane involved in apoptotic program|regulation of transport across mitochondrial membrane involved in signaling (initiator) caspase activity|regulation of mitochondrial membrane permeability involved in apoptotic programmed cell death|regulation of mitochondrial membrane permeability involved in type I programmed cell death|regulation of mitochondrial membrane permeability involved in programmed cell death by apoptosis|regulation of transport across mitochondrial membrane involved in apoptotic cell death|regulation of transport across mitochondrial membrane involved in apoptotic process|regulation of transport across mitochondrial membrane involved in programmed cell death by apoptosis|regulation of transport across mitochondrial membrane involved in apoptotic programmed cell death|regulation of mitochondrial membrane permeability involved in apoptotic cell death|regulation of mitochondrial membrane permeability involved in signaling (initiator) caspase activity|regulation of mitochondrial membrane permeability involved in apoptosis							pr	2013-05-03T12:09:35Z					biological_process											owl:Class	
GO:0044063	biolink:NamedThing	modulation by symbiont of host nervous system process	The alteration by a symbiont organism of the functioning of a host neurophysiological process, an organ system process carried out by any of the organs or tissues of neurological system.	tmpzr1t_l9r_go_relaxed.owl	regulation by symbiont of host neurological system process|modulation by symbiont of host neurological system process													biological_process											owl:Class	
GO:0097262	biolink:NamedThing	eoxin D4 synthase activity	Catalysis of the reaction: eoxin C4 = eoxin D4 + 5-L-glutamyl amino acid.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-2161945			pr	2012-03-08T03:01:00Z					molecular_function											owl:Class	
GO:0099517	biolink:NamedThing	synaptic vesicle transport along microtubule	The directed movement of synaptic vesicles along microtubules within a cell, powered by molecular motors.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0099514	biolink:NamedThing	synaptic vesicle cytoskeletal transport	The directed movement of synaptic vesicles along cytoskeletal fibers such as microfilaments or microtubules within a cell, powered by molecular motors.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0014881	biolink:NamedThing	regulation of myofibril size	Any process that modulates the size of myofibrils. A myofibril is the contractile element of skeletal and cardiac muscle. It is a long, highly organized bundle of actin, myosin, and other proteins that contracts by a sliding filament mechanism.	tmpzr1t_l9r_go_relaxed.owl	change of myofibril size													biological_process											owl:Class	
GO:0044873	biolink:NamedThing	lipoprotein localization to membrane	A process in which a lipoprotein is transported to, or maintained in, a specific location in a membrane.	tmpzr1t_l9r_go_relaxed.owl								jl	2014-11-25T16:28:43Z					biological_process											owl:Class	
GO:0048463	biolink:NamedThing	carpel structural organization	The process that contributes to the act of creating the structural organization of the carpel. This process pertains to the physical shaping of a rudimentary structure.	tmpzr1t_l9r_go_relaxed.owl	carpel structural organisation											GO:0048432		biological_process											owl:Class	
GO:0003746	biolink:NamedThing	translation elongation factor activity	Functions in chain elongation during polypeptide synthesis at the ribosome.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-192704|Reactome:R-HSA-192841							GO:0008183|GO:0008182		molecular_function											owl:Class	
GO:0034194	biolink:NamedThing	D-galactonate catabolic process	The chemical reactions and pathways resulting in the breakdown of D-galactonate, the anion of D-galactonic acid.	tmpzr1t_l9r_go_relaxed.owl	D-galactonate degradation|D-galactonate breakdown|D-galactonate catabolism				MetaCyc:GALACTCAT-PWY									biological_process											owl:Class	
GO:0034192	biolink:NamedThing	D-galactonate metabolic process	The chemical reactions and pathways involving D-galactonate, the anion of D-galactonic acid.	tmpzr1t_l9r_go_relaxed.owl	D-galactonate metabolism													biological_process											owl:Class	
GO:0047761	biolink:NamedThing	butyrate kinase activity	Catalysis of the reaction: ATP + butanoate = ADP + butanoyl phosphate + H(+).	tmpzr1t_l9r_go_relaxed.owl	ATP:butanoate 1-phosphotransferase activity				KEGG_REACTION:R01688|EC:2.7.2.7|RHEA:13585|MetaCyc:BUTYRATE-KINASE-RXN									molecular_function											owl:Class	
GO:1990788	biolink:NamedThing	GLI-SUFU complex	A protein repressing GLI's transcription factor activity when SMO signalling is inactive. Upon ligand binding to the upstream receptor PTC (Patched) GLI dissociates from SUFU and activates transcription of hedgehog-target genes. In mammals it consists of SUFU and one of the GLI family proteins.	tmpzr1t_l9r_go_relaxed.owl						An example of this is SUFU in human (Q9UMX1) in PMID:24311597 (inferred from direct assay).		bhm	2015-06-26T13:49:47Z					cellular_component											owl:Class	
GO:0033052	biolink:NamedThing	cyanoamino acid metabolic process	The chemical reactions and pathways involving cyanoamino acids, amino acid derivatives that contain a cyanide group.	tmpzr1t_l9r_go_relaxed.owl	cyanoamino acid metabolism													biological_process											owl:Class	
GO:0102640	biolink:NamedThing	paspalinine synthase activity	Catalysis of the reaction: paspalicine + O2 + NADPH + H+ <=> paspalinine + NADP + H2O.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-15738									molecular_function											owl:Class	
GO:0021592	biolink:NamedThing	fourth ventricle development	The process whose specific outcome is the progression of the fourth ventricle over time, from its formation to the mature structure. The fourth ventricle is an irregularly shaped cavity in the rhombencephalon, between the medulla oblongata, the pons, and the isthmus in front, and the cerebellum behind. It is continuous with the central canal of the cord below and with the cerebral aqueduct above, and through its lateral and median apertures it communicates with the subarachnoid space.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0044803	biolink:NamedThing	multi-organism membrane organization	A process which results in the assembly, arrangement of constituent parts, or disassembly of a membrane, involving more than one organism.	tmpzr1t_l9r_go_relaxed.owl								jl	2013-09-10T15:11:41Z					biological_process											owl:Class	
GO:0070196	biolink:NamedThing	eukaryotic translation initiation factor 3 complex assembly	The aggregation, arrangement and bonding together of a set of components to form the eukaryotic translation initiation factor 3 complex.	tmpzr1t_l9r_go_relaxed.owl	eIF-3 assembly|eIF3 assembly													biological_process											owl:Class	
GO:0004506	biolink:NamedThing	squalene monooxygenase activity	Catalysis of the reaction: H(+) + NADPH + O(2) + squalene = (S)-2,3-epoxysqualene + H(2)O + NADP(+).	tmpzr1t_l9r_go_relaxed.owl	squalene,NADPH:oxygen oxidoreductase (2,3-epoxidizing) activity|squalene 2,3-oxidocyclase activity|squalene-2,3-epoxide cyclase activity|squalene hydroxylase activity|squalene oxydocyclase activity|squalene-2,3-epoxidase activity|squalene epoxidase activity				KEGG_REACTION:R02874|EC:1.14.14.17|RHEA:25282|MetaCyc:SQUALENE-MONOOXYGENASE-RXN|Reactome:R-HSA-191299									molecular_function											owl:Class	
GO:0061765	biolink:NamedThing	modulation by virus of host NIK/NF-kappaB cascade	Any process in which a virus effect a change in the frequency, rate or extent of NIK/NF-kappaB signaling in the host.	tmpzr1t_l9r_go_relaxed.owl	modulation by virus of host NIK/NF-kappaB signaling							dph	2016-04-19T10:41:22Z					biological_process											owl:Class	
GO:0102981	biolink:NamedThing	4-hydroxy-5-methyl-2-propyl-3(2H)-furanone oxidoreductase activity	Catalysis of the reaction: 4-hydroxy-5-methyl-2-propyl-3(2H)-furanone + NADP <=> (2E)-4-hydroxy-5-methyl-2-propylidene-3(2H)-furanone + NADPH + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-9567									molecular_function											owl:Class	
GO:1900302	biolink:NamedThing	positive regulation of laminarabiose transport	Any process that activates or increases the frequency, rate or extent of laminarabiose transport.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of laminarabiose transport|upregulation of laminarabiose transport|up regulation of laminarabiose transport|activation of laminarabiose transport							tt	2012-04-05T07:57:37Z					biological_process											owl:Class	
GO:0018680	biolink:NamedThing	deethylatrazine monooxygenase activity	Catalysis of the reaction: 2 deethylatrazine + O2 = 2 CH3COCH3 + 2 deisopropyldeethylatrazine.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0128|EC:1.14.15.-									molecular_function											owl:Class	
GO:0071029	biolink:NamedThing	nuclear ncRNA surveillance	The set of processes involved in identifying and degrading defective or aberrant ncRNAs within the nucleus.	tmpzr1t_l9r_go_relaxed.owl	nuclear aberrant ncRNA catabolic process|nuclear ncRNA quality control							krc	2009-07-28T04:22:31Z					biological_process											owl:Class	
GO:0035285	biolink:NamedThing	appendage segmentation	Division of an appendage, an organ or part that is attached to the main body of an organism, into a series of semi-repetitive parts or segments. Most arthropod appendages, such as the legs and antennae, are visibly segmented.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:2000165	biolink:NamedThing	regulation of planar cell polarity pathway involved in pericardium morphogenesis	Any process that modulates the frequency, rate or extent of planar cell polarity pathway involved in pericardium morphogenesis.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-10-05T01:07:36Z					biological_process											owl:Class	
GO:0003390	biolink:NamedThing	dendrite development by retrograde extension	The progression of a dendrite over time by the attachment of a part of the neuron to an anchor and the subsequent migration of the cell body away from the anchor point.	tmpzr1t_l9r_go_relaxed.owl	dendrite retrograde extension							dph	2009-12-09T09:25:24Z					biological_process											owl:Class	
GO:0052657	biolink:NamedThing	guanine phosphoribosyltransferase activity	Catalysis of the reaction: GMP + diphosphate = guanine + 5-phospho-alpha-D-ribose 1-diphosphate.	tmpzr1t_l9r_go_relaxed.owl	guanosine phosphoribosyltransferase activity|Transphosphoribosidase activity|guanylic pyrophosphorylase activity|GPRT|6-mercaptopurine phosphoribosyltransferase activity|6-hydroxypurine phosphoribosyltransferase activity|purine-6-thiol phosphoribosyltransferase activity|guanosine 5'-phosphate pyrophosphorylase activity|guanine-hypoxanthine phosphoribosyltransferase activity|GMP pyrophosphorylase activity|guanylate pyrophosphorylase activity|hypoxanthine-guanine phosphoribosyltransferase activity				RHEA:25424|KEGG_REACTION:R01229|EC:2.4.2.8|MetaCyc:GUANPRIBOSYLTRAN-RXN									molecular_function											owl:Class	
GO:2001127	biolink:NamedThing	methane biosynthetic process from formic acid	The chemical reactions and pathways resulting in the formation of a methane from a formic acid.	tmpzr1t_l9r_go_relaxed.owl								jl	2011-10-13T09:54:03Z					biological_process											owl:Class	
GO:0098915	biolink:NamedThing	membrane repolarization during ventricular cardiac muscle cell action potential	The process in which ions are transported across a membrane such that the ventricular cardiomyocyte membrane potential changes in the direction from the positive membrane potential at the peak of the action potential towards the negative resting potential.	tmpzr1t_l9r_go_relaxed.owl	regulation of ventricular cardiac muscle repolarization|electrocardiogram T wave|ventricular repolarization													biological_process											owl:Class	
GO:0019570	biolink:NamedThing	L-arabinose catabolic process to 2-oxoglutarate	The chemical reactions and pathways resulting in the breakdown of L-arabinose into other compounds, including 2-oxoglutarate.	tmpzr1t_l9r_go_relaxed.owl	L-arabinose catabolic process to 2-ketoglutarate|L-arabinose catabolic process to alpha-oxoglutarate|L-arabinose catabolism to alpha-oxoglutarate|L-arabinose degradation to 2-oxoglutarate|L-arabinose catabolic process to alpha-ketoglutarate|L-arabinose catabolism to 2-ketoglutarate|L-arabinose breakdown to 2-oxoglutarate|L-arabinose catabolism to alpha-ketoglutarate													biological_process											owl:Class	
GO:0000966	biolink:NamedThing	RNA 5'-end processing	Any process involved in forming the mature 5' end of an RNA molecule.	tmpzr1t_l9r_go_relaxed.owl	RNA 5' end processing													biological_process											owl:Class	
GO:0047958	biolink:NamedThing	glycine:2-oxoglutarate aminotransferase activity	Catalysis of the reaction: glycine + 2-oxoglutarate = glyoxylate + L-glutamate.	tmpzr1t_l9r_go_relaxed.owl	glutamic-glyoxylic transaminase activity|glutamate-glyoxylate transaminase activity|glycine aminotransferase activity|glyoxylate-glutamate aminotransferase activity|glycine transaminase activity|glyoxylate-glutamic transaminase activity|L-glutamate:glyoxylate aminotransferase activity				EC:2.6.1.4|MetaCyc:GLYCINE-AMINOTRANSFERASE-RXN|RHEA:14089									molecular_function											owl:Class	
GO:0042140	biolink:NamedThing	late meiotic recombination nodule assembly	During meiosis, the aggregation, arrangement and bonding together of strand exchange proteins (recombinases) to form small, electron dense structures in association with meiotic chromosomes during pachytene. Involved in the catalysis crossing over.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1905003	biolink:NamedThing	picolinic acid metabolic process	The chemical reactions and pathways involving picolinic acid.	tmpzr1t_l9r_go_relaxed.owl	picolinate metabolism|picolinic acid metabolism							bf	2016-03-01T14:06:28Z					biological_process											owl:Class	
GO:0051638	biolink:NamedThing	barbed-end actin filament uncapping	The removal of capping protein from the barbed (or plus) end of actin filaments to free the ends for addition, exchange or removal of further actin subunits.	tmpzr1t_l9r_go_relaxed.owl	plus-end F-actin uncapping|barbed end actin filament uncapping|plus end F-actin uncapping|plus end actin filament uncapping|barbed-end F-actin uncapping|plus-end actin filament uncapping|barbed end F-actin uncapping													biological_process											owl:Class	
GO:1903875	biolink:NamedThing	corticosterone binding	Binding to corticosterone.	tmpzr1t_l9r_go_relaxed.owl								mr	2015-02-06T16:02:35Z					molecular_function											owl:Class	
GO:0106029	biolink:NamedThing	tRNA pseudouridine synthase activity	Catalysis of the reaction: tRNA uridine = tRNA pseudouridine. Conversion of uridine in a tRNA molecule to pseudouridine by rotation of the C1'-N-1 glycosidic bond of uridine in RNA to a C1'-C5.	tmpzr1t_l9r_go_relaxed.owl	transfer ribonucleate pseudouridine synthetase activity|tRNA pseudouridine(31) synthase|tRNA pseudouridylate synthase I activity|tRNA pseudouridine(55) synthase|tRNA pseudouridine(32) synthase|tRNA-pseudouridine synthase activity|transfer RNA pseudouridine synthetase activity|tRNA pseudouridine(38-40) synthase|Mitochondrial tRNA pseudouridine(27/28) synthase|tRNA-uridine uracilmutase activity|tRNA pseudouridine(13) synthase|tRNA pseudouridine(38/39) synthase|tRNA-pseudouridine synthase I activity|tRNA-uridine isomerase activity|tRNA pseudouridine(65) synthase				EC:5.4.99.27|EC:5.4.99.42|RHEA:22376|EC:5.4.99.45|EC:5.4.99.26|EC:5.4.99.28|MetaCyc:TRNA-PSEUDOURIDINE-SYNTHASE-I-RXN|EC:5.4.99.12|EC:5.4.99.25|EC:5.4.99.44			hjd	2017-06-26T17:37:30Z					molecular_function											owl:Class	
GO:0002570	biolink:NamedThing	somatic diversification of immunoglobulin genes by N region addition	The addition of variable numbers of random nucleotides by terminal deoxytransferase in the N regions of heavy chain immunoglobulin genes. N regions are found at the V-D and D-J recombinational junctions.	tmpzr1t_l9r_go_relaxed.owl	somatic diversification of antibody genes by N region addition													biological_process											owl:Class	
GO:0034105	biolink:NamedThing	positive regulation of tissue remodeling	Any process that activates or increases the frequency, rate, or extent of tissue remodeling.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0106334	biolink:NamedThing	3'-deoxyribose phosphate lyase activity	Catalysis of the conversion of a 3'-deoxyribose phosphate in DNA to a 3'-phosphate.	tmpzr1t_l9r_go_relaxed.owl	3'-dRP lyase|3'-dRP lyase activity							hjd	2020-10-20T19:04:24Z					molecular_function											owl:Class	
GO:0015818	biolink:NamedThing	isoleucine transport	The directed movement of isoleucine, (2R*,3R*)-2-amino-3-methylpentanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	L-isoleucine transport													biological_process											owl:Class	
GO:0098691	biolink:NamedThing	dopaminergic synapse	A synapse that uses dopamine as a neurotransmitter.	tmpzr1t_l9r_go_relaxed.owl								dos	2017-03-07T14:51:52Z					cellular_component											owl:Class	
GO:0102438	biolink:NamedThing	laricitrin 4'-O-methyltransferase activity	Catalysis of the reaction: laricitrin(1-) + S-adenosyl-L-methionine  <=> H+ + 3',4'-dimethylmyricetin + S-adenosyl-L-homocysteine.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-13914									molecular_function											owl:Class	
GO:0003039	biolink:NamedThing	detection of reduced oxygen by carotid body chemoreceptor signaling	The process in which information about the levels of oxygen are received and are converted to a molecular signal by chemoreceptors in a carotid body.	tmpzr1t_l9r_go_relaxed.owl	detection of reduced oxygen by carotid body chemoreceptor signalling													biological_process											owl:Class	
GO:0003020	biolink:NamedThing	detection of reduced oxygen by chemoreceptor signaling	The process in which information about the levels of oxygen are received and are converted to a molecular signal by chemoreceptors in the carotid bodies and the aortic bodies.	tmpzr1t_l9r_go_relaxed.owl	detection of reduced oxygen by chemoreceptor signalling													biological_process											owl:Class	
GO:0000006	biolink:NamedThing	high-affinity zinc transmembrane transporter activity	Enables the transfer of zinc ions (Zn2+) from one side of a membrane to the other, probably powered by proton motive force. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.	tmpzr1t_l9r_go_relaxed.owl	high-affinity zinc uptake transmembrane transporter activity|high affinity zinc uptake transmembrane transporter activity													molecular_function											owl:Class	
GO:0001523	biolink:NamedThing	retinoid metabolic process	The chemical reactions and pathways involving retinoids, any member of a class of isoprenoids that contain or are derived from four prenyl groups linked head-to-tail. Retinoids include retinol and retinal and structurally similar natural derivatives or synthetic compounds, but need not have vitamin A activity.	tmpzr1t_l9r_go_relaxed.owl	retinoid metabolism													biological_process											owl:Class	
GO:0060718	biolink:NamedThing	chorionic trophoblast cell differentiation	The process in which relatively unspecialized cells of the ectoplacental cone acquire specialized structural and/or functional features that characterize chorionic trophoblasts. These cells will migrate towards the spongiotrophoblast layer and give rise to syncytiotrophoblasts of the labyrinthine layer.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-06-11T02:48:27Z					biological_process											owl:Class	
GO:1903413	biolink:NamedThing	cellular response to bile acid	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bile acid stimulus.	tmpzr1t_l9r_go_relaxed.owl								rl	2014-09-03T12:45:51Z					biological_process											owl:Class	
GO:0090249	biolink:NamedThing	regulation of cell migration involved in somitogenic axis elongation	Any process that modulates the frequency, rate, or extent of the controlled self-propelled movement of a cell that contributes to somitogenic axis elongation.	tmpzr1t_l9r_go_relaxed.owl	regulation of cell motility involved in somitogenic axis elongation	https://github.com/geneontology/go-annotation/issues/2040						tb	2010-01-22T11:20:05Z					biological_process											owl:Class	
GO:0052728	biolink:NamedThing	capsorubin synthase activity	Catalysis of the reaction: violaxanthin = capsorubin.	tmpzr1t_l9r_go_relaxed.owl	violaxanthin-capsorubin isomerase (ketone-forming) activity|CCS|capsanthin-capsorubin synthase activity|ketoxanthophyll synthase activity				MetaCyc:RXN-7946|EC:5.3.99.8|RHEA:21752			ai	2011-08-16T03:09:26Z					molecular_function											owl:Class	
GO:0042793	biolink:NamedThing	plastid transcription	The synthesis of RNA from a plastid DNA template, usually by a specific plastid RNA polymerase.	tmpzr1t_l9r_go_relaxed.owl	transcription from plastid promoter	https://github.com/geneontology/go-ontology/issues/14854												biological_process											owl:Class	
GO:0015705	biolink:NamedThing	iodide transport	The directed movement of iodide into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0031918	biolink:NamedThing	positive regulation of synaptic metaplasticity	A process that increases synaptic metaplasticity. Metaplasticity is a higher-order form of plasticity and is manifest as a change in the ability to induce subsequent synaptic plasticity that is the ability of synapses to change as circumstances require.	tmpzr1t_l9r_go_relaxed.owl	activation of synaptic metaplasticity|up-regulation of synaptic metaplasticity|up regulation of synaptic metaplasticity|upregulation of synaptic metaplasticity|stimulation of synaptic metaplasticity													biological_process											owl:Class	
GO:0044594	biolink:NamedThing	17-beta-hydroxysteroid dehydrogenase (NAD+) activity	Catalysis of the reaction: a 17-beta-hydroxysteroid + NAD+ = a 17-oxosteroid + NADH + H+.	tmpzr1t_l9r_go_relaxed.owl					RHEA:24612			jl	2012-04-26T04:49:13Z					molecular_function											owl:Class	
GO:0015312	biolink:NamedThing	polyamine:proton antiporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + polyamine(in) = H+(in) + polyamine(out).	tmpzr1t_l9r_go_relaxed.owl	polyamine:hydrogen antiporter activity													molecular_function											owl:Class	
GO:0070525	biolink:NamedThing	tRNA threonylcarbamoyladenosine metabolic process	The chemical reactions and pathways involving tRNA threonylcarbamoyladenosine, a modified nucleoside found in some tRNA molecules.	tmpzr1t_l9r_go_relaxed.owl	t6A metabolic process|t6A metabolism|threonylcarbamoyladenosine metabolism													biological_process											owl:Class	
GO:0018832	biolink:NamedThing	halohydrin hydrogen-halide-lyase B activity	Catalysis of the elimination of HCl from a chloropropanol, yielding an epoxypropane.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_enzymeID:e0050									molecular_function											owl:Class	
GO:0019181	biolink:NamedThing	halohydrin hydrogen-halide-lyase activity	Catalysis of the reaction: a halohydrin = an epoxide + a hydrogen halide.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0008463	biolink:NamedThing	formylmethionine deformylase activity	Catalysis of the reaction: N-formyl-L-methionine + H(2)O = L-methionine + formate.	tmpzr1t_l9r_go_relaxed.owl	N-formyl-L-methionine amidohydrolase activity				RHEA:17781|KEGG_REACTION:R00653|EC:3.5.1.31|MetaCyc:FORMYLMETHIONINE-DEFORMYLASE-RXN									molecular_function											owl:Class	
GO:0002650	biolink:NamedThing	negative regulation of tolerance induction to self antigen	Any process that stops, prevents, or reduces the frequency, rate, or extent of tolerance induction to self antigen.	tmpzr1t_l9r_go_relaxed.owl	inhibition of tolerance induction to self antigen|downregulation of tolerance induction to self antigen|down regulation of tolerance induction to self antigen|down-regulation of tolerance induction to self antigen													biological_process											owl:Class	
GO:0044020	biolink:NamedThing	histone methyltransferase activity (H4-R3 specific)	Catalysis of the reaction: S-adenosyl-L-methionine + (histone H4)-arginine (position 3) = S-adenosyl-L-homocysteine + (histone H4)-N-methyl-arginine (position 3). This reaction is the addition of a methyl group to arginine at position 3 of histone H4.	tmpzr1t_l9r_go_relaxed.owl	histone-arginine N-methyltransferase activity (H4-R3 specific)|histone methylase activity (H4-R3 specific)													molecular_function											owl:Class	
GO:0022877	biolink:NamedThing	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity	Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + fructose(out) = protein histidine + fructose phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.	tmpzr1t_l9r_go_relaxed.owl	fructose PTS transporter activity													molecular_function											owl:Class	
GO:1990235	biolink:NamedThing	diamine N-acetyltransferase complex	A protein complex which is capable of diamine N-acetyltransferase activity.	tmpzr1t_l9r_go_relaxed.owl	SAT tetramer|spermidine acetyltransferase complex|SAT complex							bhm	2013-11-13T16:29:45Z					cellular_component											owl:Class	
GO:2000970	biolink:NamedThing	regulation of detection of glucose	Any process that modulates the frequency, rate or extent of detection of glucose.	tmpzr1t_l9r_go_relaxed.owl	regulation of glucose sensing|regulation of glucose perception|regulation of glucose detection							vk	2011-08-02T10:18:52Z					biological_process											owl:Class	
GO:0036335	biolink:NamedThing	intestinal stem cell homeostasis	Any biological process involved in the maintenance of the steady-state number of intestinal stem cells within a population of cells.	tmpzr1t_l9r_go_relaxed.owl								bf	2012-09-05T10:23:41Z					biological_process											owl:Class	
GO:2000255	biolink:NamedThing	negative regulation of male germ cell proliferation	Any process that stops, prevents or reduces the frequency, rate or extent of male germ cell proliferation.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-11-18T09:29:47Z					biological_process											owl:Class	
GO:0005043	biolink:NamedThing	netrin receptor activity involved in chemorepulsion	Combining with a netrin signal and transmitting the signal from one side of the membrane to the other to contribute to the directed movement of a motile cell away from a higher concentration of netrin.	tmpzr1t_l9r_go_relaxed.owl	repulsive netrin receptor activity|netrin receptor activity involved in negative chemotaxis													molecular_function											owl:Class	
GO:0005042	biolink:NamedThing	netrin receptor activity	Combining with a netrin signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0051431	biolink:NamedThing	corticotropin-releasing hormone receptor 2 binding	Binding to a corticotropin-releasing hormone receptor type 2 (CRHR2). The CRHR2 has several splice variants that are located in sub-cortical areas of the brain and in the periphery.	tmpzr1t_l9r_go_relaxed.owl	CRHR2 binding|type 2 corticotropin-releasing factor receptor binding|type 2 corticotropin releasing factor receptor ligand|type 2 corticotropin releasing factor receptor binding											GO:0031744		molecular_function											owl:Class	
GO:0014872	biolink:NamedThing	myoblast division	The process resulting in the physical partitioning and separation of a myoblast into daughter cells. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0043929	biolink:NamedThing	primary ovarian follicle growth involved in double layer follicle stage	Increase in size of primary follicles including oocyte growth and granulosa and/or theca cell proliferation until more than one layer of granulosa cells is present (preantral follicle), as part of the double layer follicle stage of oogenesis.	tmpzr1t_l9r_go_relaxed.owl	primary ovarian follicle growth during double layer follicle stage													biological_process											owl:Class	
GO:0097553	biolink:NamedThing	calcium ion transmembrane import into cytosol	A process in which a calcium ion is transported from one side of a membrane to the other into the cytosol by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	calcium transmembrane import into cytosol							pr	2014-01-23T11:05:13Z					biological_process											owl:Class	
GO:0047582	biolink:NamedThing	4-methyleneglutaminase activity	Catalysis of the reaction: 4-methylene-L-glutamine + H(2)O = 4-methylene-L-glutamate + NH(4)(+).	tmpzr1t_l9r_go_relaxed.owl	4-methyleneglutamine amidohydrolase activity|4-methyleneglutamine deamidase activity|4-methylene-L-glutamine amidohydrolase activity				KEGG_REACTION:R02712|RHEA:14741|EC:3.5.1.67|MetaCyc:4-METHYLENEGLUTAMINASE-RXN									molecular_function											owl:Class	
GO:0035501	biolink:NamedThing	MH1 domain binding	Binding to a MH1 (MAD homology 1) protein domain. The MH1 domain is found at the amino terminus of MAD related proteins such as Smads and can mediate DNA binding in some proteins. Smads also use the MH1 domain to interact with some transcription factors.	tmpzr1t_l9r_go_relaxed.owl	MAD homology 1 domain binding							bf	2010-04-29T03:17:27Z					molecular_function											owl:Class	
GO:0010931	biolink:NamedThing	macrophage tolerance induction	A process involving any mechanism for tolerance induction in macrophages.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0110017	biolink:NamedThing	cap-independent translational initiation of linear mRNA	The process where translation initiation recruits the 40S ribosomal subunits in a cap and 5' end independent fashion before an AUG codon is encountered in an appropriate sequence context to initiate linear mRNA translation.	tmpzr1t_l9r_go_relaxed.owl								kmv	2017-06-08T15:13:55Z					biological_process											owl:Class	
GO:0033835	biolink:NamedThing	flavanone 7-O-glucoside 2''-O-beta-L-rhamnosyltransferase activity	Catalysis of the reaction: UDP-L-rhamnose + a flavanone 7-O-glucoside = UDP + a flavanone 7-O-[beta-L-rhamnosyl-(1->2)-beta-D-glucoside].	tmpzr1t_l9r_go_relaxed.owl	UDP-L-rhamnose:flavanone-7-O-glucoside 2''-O-beta-L-rhamnosyltransferase activity|UDP-rhamnose:flavanone-7-O-glucoside-2''-O-rhamnosyltransferase activity|1->2 UDP-rhamnosyltransferase activity				MetaCyc:RXN-5002|MetaCyc:RXN-7759|MetaCyc:RXN-5004|EC:2.4.1.236|MetaCyc:RXN-9699|RHEA:15473|MetaCyc:RXN-5001									molecular_function											owl:Class	
GO:1990725	biolink:NamedThing	cord factor receptor activity	Combining with a cord factor, an M. tuberculosis cell wall glycolipid, and transmitting a signal from one side of the membrane to the other to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	TMD receptor activity|trehalose 6,6'-dimycolate receptor activity				Wikipedia:Cord_factor			hjd	2015-04-07T20:53:31Z					molecular_function											owl:Class	
GO:0051629	biolink:NamedThing	inhibition of epinephrine uptake	Any process that prevents the activation of the directed movement of epinephrine into a cell.	tmpzr1t_l9r_go_relaxed.owl	inhibition of epinephrine import|inhibition of adrenaline uptake													biological_process											owl:Class	
GO:0061529	biolink:NamedThing	epinephrine secretion, neurotransmission	The regulated release of epinephrine by a cell in which the epinephrine acts as a neurotransmitter.	tmpzr1t_l9r_go_relaxed.owl	adrenaline secretion, neurotransmission							dph	2013-06-21T15:47:22Z					biological_process											owl:Class	
GO:0018579	biolink:NamedThing	protocatechuate 4,5-dioxygenase activity	Catalysis of the reaction: protocatechuate + O2 = 4-carboxy-2-hydroxymuconate semialdehyde.	tmpzr1t_l9r_go_relaxed.owl	protocatechuic 4,5-dioxygenase activity|protocatechuate 4,5-oxygenase activity|protocatechuate:oxygen 4,5-oxidoreductase (decyclizing)|protocatechuic 4,5-oxygenase activity				UM-BBD_reactionID:r0144|RHEA:24044|MetaCyc:PROTOCATECHUATE-45-DIOXYGENASE-RXN|EC:1.13.11.8									molecular_function											owl:Class	
GO:0032904	biolink:NamedThing	negative regulation of nerve growth factor production	Any process that stops, prevents, or reduces the frequency, rate, or extent of production of nerve growth factor (NGF).	tmpzr1t_l9r_go_relaxed.owl	negative regulation of NGF production|inhibition of nerve growth factor production|down-regulation of nerve growth factor production|downregulation of nerve growth factor production|down regulation of nerve growth factor production													biological_process											owl:Class	
GO:0103057	biolink:NamedThing	gibberellin A19, 2-oxoglutarate:oxygen oxidoreductase activity	Catalysis of the reaction: gibberellin A19 + O2 + 2-oxoglutarate <=> H+ + gibberellin A20 + 2 carbon dioxide + succinate.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN1F-169									molecular_function											owl:Class	
GO:0010146	biolink:NamedThing	fructan biosynthetic process	The chemical reactions and pathways resulting in the formation of fructan a polysaccharide consisting of fructose residues.	tmpzr1t_l9r_go_relaxed.owl	fructan formation|levan biosynthesis|fructan biosynthesis|fructan synthesis|levan biosynthetic process|fructan anabolism				MetaCyc:PWY-822									biological_process											owl:Class	
GO:0014812	biolink:NamedThing	muscle cell migration	The orderly movement of a muscle cell from one site to another, often during the development of a multicellular organism.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0004730	biolink:NamedThing	pseudouridylate synthase activity	Catalysis of the reaction: D-ribose 5-phosphate + uracil = H(2)O + pseudouridine 5'-phosphate.	tmpzr1t_l9r_go_relaxed.owl	pseudouridine monophosphate synthetase activity|pseudouridylic acid synthetase activity|uracil hydro-lyase (adding D-ribose 5-phosphate; pseudouridine-5'-phosphate-forming)|uracil hydro-lyase (adding D-ribose 5-phosphate)|pseudouridine monophosphate synthase activity|pseudouridylate synthetase activity|uracil hydrolyase activity|5-ribosyluracil 5-phosphate synthetase activity|psiUMP synthetase activity|pseudouridine-5'-phosphate glycosidase activity				EC:4.2.1.70|RHEA:18337|KEGG_REACTION:R01055|MetaCyc:PSEUDOURIDYLATE-SYNTHASE-RXN	Note that this term should not be confused with 'pseudouridine synthase activity ; GO:0009982', which refers to the intramolecular isomerization of uridine to pseudouridine.								molecular_function											owl:Class	
GO:1904418	biolink:NamedThing	regulation of telomeric loop formation	Any process that modulates the frequency, rate or extent of telomeric loop formation.	tmpzr1t_l9r_go_relaxed.owl	regulation of t-loop formation|regulation of t-loop biosynthesis							nc	2015-07-01T10:40:24Z					biological_process											owl:Class	
GO:0009673	biolink:NamedThing	low-affinity phosphate transmembrane transporter activity	Enables the transfer of phosphate from one side of a membrane to the other. In low-affinity transport the transporter is able to bind the solute only if it is present at very high concentrations.	tmpzr1t_l9r_go_relaxed.owl	low affinity phosphate transmembrane transporter activity													molecular_function											owl:Class	
GO:0031496	biolink:NamedThing	positive regulation of mating type switching	Any process that activates or increases the frequency, rate or extent of mating type switching.	tmpzr1t_l9r_go_relaxed.owl	stimulation of mating type switching|activation of mating type switching|upregulation of mating type switching|up regulation of mating type switching|up-regulation of mating type switching													biological_process											owl:Class	
GO:0039532	biolink:NamedThing	negative regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway	Any process that stops, prevents, or reduces the frequency, rate or extent of the series of molecular signals generated as a consequence of a virus or viral RNA binding to a pattern recognition receptor (PRR) located in the cytoplasm.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of viral-induced cytoplasmic pattern recognition receptor signalling pathway|negative regulation of cytoplasmic pattern recognition receptor signaling pathway in response to virus|negative regulation of MAVS signaling							bf	2012-01-03T11:14:48Z					biological_process											owl:Class	
GO:0035229	biolink:NamedThing	positive regulation of glutamate-cysteine ligase activity	Any process that activates or increases the activity of glutamate-cysteine ligase, typically by lowering its sensitivity to inhibition by glutathione and by increasing its affinity for glutamate.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of glutamate-cysteine ligase activity|stimulation of glutamate-cysteine ligase activity|upregulation of glutamate-cysteine ligase activity|up regulation of glutamate-cysteine ligase activity|activation of glutamate-cysteine ligase activity													biological_process											owl:Class	
GO:0033521	biolink:NamedThing	phytyl diphosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of phytyl diphosphate, (2E)-3,7,11,15-tetramethylhexadec-2-en-1-yl trihydrogen diphosphate.	tmpzr1t_l9r_go_relaxed.owl	phytyl diphosphate anabolism|phytyl diphosphate formation|phytyl diphosphate biosynthesis|phytyl diphosphate synthesis				MetaCyc:PWY-5063									biological_process											owl:Class	
GO:0033424	biolink:NamedThing	CCG codon-amino acid adaptor activity	A triplet codon-amino acid adaptor activity that recognizes a CCG codon.	tmpzr1t_l9r_go_relaxed.owl	proline tRNA					Note that in the standard genetic code, CCG codes for proline.								molecular_function											owl:Class	
GO:0070693	biolink:NamedThing	P-TEFb-cap methyltransferase complex	A protein complex that is formed by the association of positive transcription elongation factor complex b (P-TEFb) with the mRNA capping methyltransferase.	tmpzr1t_l9r_go_relaxed.owl	P-TEFb-Pcm1 complex|Cdk9-Pcm1 complex							mah	2009-06-04T02:38:58Z					cellular_component											owl:Class	
GO:0005175	biolink:NamedThing	CD27 receptor binding	Binding to a CD27, a receptor found on the surface of T cells and some B cells and NK cells.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0009274	biolink:NamedThing	peptidoglycan-based cell wall	A protective structure outside the cytoplasmic membrane composed of peptidoglycan (also known as murein), a molecule made up of a glycan (sugar) backbone of repetitively alternating N-acetylglucosamine and N-acetylmuramic acid with short, attached, cross-linked peptide chains containing unusual amino acids. An example of this component is found in Escherichia coli.	tmpzr1t_l9r_go_relaxed.owl	murein sacculus|peptidoglycan|envelope													cellular_component											owl:Class	
GO:0039507	biolink:NamedThing	suppression by virus of host molecular function	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of the functional activity of a host protein.	tmpzr1t_l9r_go_relaxed.owl	inhibition of host protein function|negative regulation by virus of host molecular function|inhibition by virus of host protein function|down-regulation by virus of host protein function|negative regulation by virus of host protein function|down regulation by virus of host protein function							bf	2011-06-02T02:47:03Z					biological_process											owl:Class	
GO:0070675	biolink:NamedThing	hypoxanthine oxidase activity	Catalysis of the reaction: hypoxanthine + H2O + O2 = xanthine + H2O2.	tmpzr1t_l9r_go_relaxed.owl	hypoxanthine:oxygen oxidoreductase activity|hypoxanthine:O2 oxidoreductase activity|schardinger enzyme|hypoxanthine-xanthine oxidase activity|xanthine oxidoreductase activity|Schardinger enzyme activity|hypoxanthine:O(2) oxidoreductase activity							mah	2009-05-29T01:12:55Z					molecular_function											owl:Class	
GO:0070466	biolink:NamedThing	alpha2-beta1 integrin-alpha3(VI) complex	A protein complex that consists of an alpha2-beta1 integrin complex bound to a type VI collagen triple helix containing an alpha3(VI) chain.	tmpzr1t_l9r_go_relaxed.owl	ITGA2-ITGB1-COL6A3 complex													cellular_component											owl:Class	
GO:0080179	biolink:NamedThing	1-methylguanosine metabolic process	The chemical reactions and pathways involving 1-methylguanosine.	tmpzr1t_l9r_go_relaxed.owl								dhl	2011-04-28T04:38:13Z					biological_process											owl:Class	
GO:1900067	biolink:NamedThing	regulation of cellular response to alkaline pH	Any process that modulates the frequency, rate or extent of cellular response to alkalinity.	tmpzr1t_l9r_go_relaxed.owl	regulation of cellular response to alkalinity|regulation of cellular response to basic pH							pr	2012-01-26T02:34:59Z					biological_process											owl:Class	
GO:0035572	biolink:NamedThing	N-terminal peptidyl-serine dimethylation	The dimethylation of the N-terminal serine of proteins to form the derivative N,N-dimethylserine.	tmpzr1t_l9r_go_relaxed.owl								bf	2010-08-06T02:00:17Z					biological_process											owl:Class	
GO:0097664	biolink:NamedThing	SCF-Grr1/Pof2 ubiquitin ligase complex	An SCF ubiquitin ligase complex in which the F-box protein is Grr1 in S. cerevisiae (Pof2 in S. pombe).	tmpzr1t_l9r_go_relaxed.owl								pr	2014-10-06T10:27:10Z					cellular_component											owl:Class	
GO:0120214	biolink:NamedThing	negative regulation of histidine biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of histidine biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	down regulation of histidine biosynthetic process|inhibition of histidine biosynthetic process|down regulation of histidine formation|down-regulation of histidine anabolism|inhibition of histidine synthesis|downregulation of histidine biosynthesis|down regulation of histidine biosynthesis|downregulation of histidine formation|down-regulation of histidine biosynthesis|downregulation of histidine synthesis|downregulation of histidine anabolism|inhibition of histidine anabolism|down-regulation of histidine biosynthetic process|negative regulation of histidine anabolism|negative regulation of histidine formation|inhibition of histidine biosynthesis|negative regulation of histidine synthesis|down-regulation of histidine synthesis|downregulation of histidine biosynthetic process|down regulation of histidine anabolism|negative regulation of histidine biosynthesis|down regulation of histidine synthesis|down-regulation of histidine formation|inhibition of histidine formation							krc	2019-06-27T20:56:35Z					biological_process											owl:Class	
GO:0019629	biolink:NamedThing	propionate catabolic process, 2-methylcitrate cycle	The chemical reactions and pathways resulting in the breakdown of propionate that occurs in the 2-methylcitrate cycle.	tmpzr1t_l9r_go_relaxed.owl	propionate degradation, 2-methylcitrate cycle|propionate breakdown, 2-methylcitrate cycle													biological_process											owl:Class	
GO:0071919	biolink:NamedThing	G-quadruplex DNA formation	A DNA metabolic process that results in the formation of G-quadruplex DNA structures, in which groups of four guanines adopt a flat, cyclic Hoogsteen hydrogen-bonding arrangement known as a guanine tetrad or G-quartet. The stacking of several layers of G-quartets forms G-quadruplexes, in which one or more DNA single strands are assembled in parallel and/or antiparallel, with interactions that can be either intra- or intermolecular in nature.	tmpzr1t_l9r_go_relaxed.owl	G quadruplex DNA formation|G-quartet DNA formation|G quartet DNA formation							mah	2010-09-24T10:57:43Z					biological_process											owl:Class	
GO:1905753	biolink:NamedThing	positive regulation of argininosuccinate synthase activity	Any process that activates or increases the frequency, rate or extent of argininosuccinate synthase activity.	tmpzr1t_l9r_go_relaxed.owl	activation of arginosuccinate synthetase activity|up regulation of L-citrulline:L-aspartate ligase (AMP-forming)|activation of argininosuccinate synthase activity|positive regulation of argininosuccinate synthetase activity|up-regulation of argininosuccinic acid synthetase activity|up regulation of arginine succinate synthetase activity|up regulation of arginosuccinate synthetase activity|activation of L-citrulline:L-aspartate ligase (AMP-forming)|positive regulation of L-citrulline:L-aspartate ligase (AMP-forming)|up regulation of argininosuccinate synthetase activity|positive regulation of arginosuccinate synthetase activity|up-regulation of argininosuccinate synthase activity|up-regulation of citrulline--aspartate ligase activity|positive regulation of citrulline--aspartate ligase activity|positive regulation of argininosuccinic acid synthetase activity|activation of citrulline--aspartate ligase activity|up regulation of citrulline--aspartate ligase activity|upregulation of argininosuccinate synthase activity|up-regulation of L-citrulline:L-aspartate ligase (AMP-forming)|upregulation of arginine succinate synthetase activity|activation of argininosuccinic acid synthetase activity|activation of arginine succinate synthetase activity|positive regulation of arginine succinate synthetase activity|activation of argininosuccinate synthetase activity|up regulation of argininosuccinate synthase activity|upregulation of L-citrulline:L-aspartate ligase (AMP-forming)|up regulation of argininosuccinic acid synthetase activity|up-regulation of argininosuccinate synthetase activity|upregulation of arginosuccinate synthetase activity|upregulation of argininosuccinic acid synthetase activity|up-regulation of arginosuccinate synthetase activity|upregulation of argininosuccinate synthetase activity|up-regulation of arginine succinate synthetase activity|upregulation of citrulline--aspartate ligase activity							dos	2016-12-12T11:44:09Z					biological_process											owl:Class	
GO:0045221	biolink:NamedThing	negative regulation of FasL production	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of FasL.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of FasL biosynthetic process|inhibition of FasL biosynthetic process|negative regulation of FasL anabolism|down regulation of FasL biosynthetic process|negative regulation of FasL formation|downregulation of FasL biosynthetic process|negative regulation of FasL biosynthesis|negative regulation of FasL biosynthetic process|negative regulation of FasL synthesis													biological_process											owl:Class	
GO:0002145	biolink:NamedThing	4-amino-5-hydroxymethyl-2-methylpyrimidine diphosphatase activity	Catalysis of the reaction: 4-amino-5-hydroxymethyl-2-methylpyrimidine pyrophosphate + H2O = hydroxymethylpyrimidine phosphate + phosphate + H(+).	tmpzr1t_l9r_go_relaxed.owl	HMP-PP pyrophosphatase|HMP-PP diphosphatase				RHEA:27914|MetaCyc:RXN0-3543			hjd	2009-06-10T11:21:35Z					molecular_function											owl:Class	
GO:0150060	biolink:NamedThing	amylin receptor 2 signaling pathway	A series of molecular signals initiated by an extracellular amylin, or another ligand, combining with an amylin receptor 2 (AMY2), a G protein-coupled receptor complex, on the surface of the target cell. The AMY2 signaling pathway can also be initiated by adrenomedullin (AM/ADM).	tmpzr1t_l9r_go_relaxed.owl	AMY2 signaling pathway							bc	2018-06-21T11:00:22Z					biological_process											owl:Class	
GO:1990575	biolink:NamedThing	mitochondrial L-ornithine transmembrane transport	The process in which L-ornithine is transported across a mitochondrial membrane, into or out of the mitochondrion.	tmpzr1t_l9r_go_relaxed.owl	mitochondrial ornithine transport|mitochondrial ornithine transmembrane transport							mah	2014-12-05T11:29:49Z			GO:0000066		biological_process											owl:Class	
GO:0047883	biolink:NamedThing	ethanolamine oxidase activity	Catalysis of the reaction: ethanolamine + H2O + O2 = glycolaldehyde + NH3 + H2O2.	tmpzr1t_l9r_go_relaxed.owl	ethanolamine:oxygen oxidoreductase (deaminating)				MetaCyc:ETHANOLAMINE-OXIDASE-RXN|EC:1.4.3.8|RHEA:18581									molecular_function											owl:Class	
GO:0044682	biolink:NamedThing	archaeal-specific GTP cyclohydrolase activity	Catalysis of the reaction: GTP + H2O <=> 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate + diphosphate +formate + H+. This activity is part of the biosynthesis of methanopterin in Archaea, and requires Fe2+.	tmpzr1t_l9r_go_relaxed.owl	Fe(2+)-dependent archaeal-specific GTP cyclohydrolase activity|MptA activity							jl	2012-08-15T11:18:40Z					molecular_function											owl:Class	
GO:0006336	biolink:NamedThing	DNA replication-independent chromatin assembly	The formation of chromatin outside the context of DNA replication.	tmpzr1t_l9r_go_relaxed.owl	DNA replication-independent nucleosome assembly|transcription-coupled nucleosome assembly	https://github.com/geneontology/go-ontology/issues/22130												biological_process											owl:Class	
GO:0055078	biolink:NamedThing	sodium ion homeostasis	Any process involved in the maintenance of an internal steady state of sodium ions within an organism or cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0001766	biolink:NamedThing	membrane raft polarization	The clustering and aggregation of a membrane into domains. This serves as a mechanism to compartmentalize cellular activities and to establish cell polarity.	tmpzr1t_l9r_go_relaxed.owl	membrane polarization|lipid raft polarization	https://github.com/geneontology/go-ontology/issues/20666												biological_process											owl:Class	
GO:0071963	biolink:NamedThing	establishment or maintenance of cell polarity regulating cell shape	Any cellular process that results in the specification, formation or maintenance of a polarized intracellular organization or cell growth patterns that regulate the shape of a cell.	tmpzr1t_l9r_go_relaxed.owl								mah	2011-06-21T03:47:21Z					biological_process											owl:Class	
GO:0097336	biolink:NamedThing	response to risperidone	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a risperidone stimulus.	tmpzr1t_l9r_go_relaxed.owl								pr	2012-06-12T11:04:31Z					biological_process											owl:Class	
GO:0050010	biolink:NamedThing	isovitexin beta-glucosyltransferase activity	Catalysis of the reaction: isovitexin + UDP-D-glucose = H(+) + isovitexin 2''-O-beta-D-glucoside + UDP.	tmpzr1t_l9r_go_relaxed.owl	uridine diphosphoglucose-isovitexin 2''-glucosyltransferase activity|isovitexin b-glucosyltransferase activity|UDP-glucose:isovitexin 2''-O-beta-D-glucosyltransferase activity|UDPglucose:isovitexin 2''-O-beta-D-glucosyltransferase activity				MetaCyc:ISOVITEXIN-BETA-GLUCOSYLTRANSFERASE-RXN|KEGG_REACTION:R03686|EC:2.4.1.106|RHEA:19529									molecular_function											owl:Class	
GO:0072326	biolink:NamedThing	vulval cell fate determination	The process in which a cell becomes capable of differentiating autonomously into a nematode vulval cell regardless of its environment; upon determination, the cell fate cannot be reversed. In nematodes, the vulva is formed from ventral epidermal cells during larval stages to give rise to a fully formed adult vulva, which is the egg-laying organ of female and hermaphrodite nematodes.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-11-01T02:04:46Z					biological_process											owl:Class	
GO:1990515	biolink:NamedThing	3' transitive RNA interference	An RNA interference where the silencing signal spreads 3' along the target mRNA, outside of the initial target sequence. Typically involves the formation of secondary siRNAs formed when the initial mRNA target sequence functions as a template for 5' to 3' synthesis of new dsRNA.	tmpzr1t_l9r_go_relaxed.owl								jl	2014-10-09T15:31:01Z					biological_process											owl:Class	
GO:0036453	biolink:NamedThing	transitive RNA interference	An RNA interference where the silencing signal spreads along the target mRNA in a 5' or 3' direction, outside of the initial target sequence.	tmpzr1t_l9r_go_relaxed.owl	transitive RNAi							bf	2013-11-07T11:14:03Z					biological_process											owl:Class	
GO:0017032	biolink:NamedThing	amino acid:potassium symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: amino acid(out) + K+(out) = amino acid(in) + K+(in).	tmpzr1t_l9r_go_relaxed.owl	potassium:amino acid symporter activity													molecular_function											owl:Class	
GO:0019705	biolink:NamedThing	protein-cysteine S-myristoyltransferase activity	Catalysis of the transfer of a myristoyl (systematic name, tetradecanoyl) group to a sulfur atom on a cysteine residue of a protein molecule in the reaction: tetradecanoyl-CoA + L-cysteinyl-[protein] = CoA + S-tetradecanoyl-L-cysteinyl-[protein].	tmpzr1t_l9r_go_relaxed.owl					RHEA:59736									molecular_function											owl:Class	
GO:0045092	biolink:NamedThing	interleukin-18 receptor complex	A protein complex that binds interleukin-18; comprises an alpha and a beta subunit.	tmpzr1t_l9r_go_relaxed.owl	IL-18 receptor complex													cellular_component											owl:Class	
GO:0035041	biolink:NamedThing	sperm DNA decondensation	Unwinding of the condensed nuclear chromatin of an inactive sperm nucleus.	tmpzr1t_l9r_go_relaxed.owl	sperm chromatin decondensation													biological_process											owl:Class	
GO:1903684	biolink:NamedThing	regulation of border follicle cell migration	Any process that modulates the frequency, rate or extent of border follicle cell migration.	tmpzr1t_l9r_go_relaxed.owl	regulation of border cell migration							als	2014-12-01T13:35:39Z					biological_process											owl:Class	
GO:0006043	biolink:NamedThing	glucosamine catabolic process	The chemical reactions and pathways resulting in the breakdown of glucosamine (2-amino-2-deoxyglucopyranose), an aminodeoxysugar that occurs in combined form in chitin.	tmpzr1t_l9r_go_relaxed.owl	glucosamine degradation|chitosamine catabolic process|glucosamine breakdown|chitosamine catabolism|glucosamine catabolism				MetaCyc:GLUAMCAT-PWY									biological_process											owl:Class	
GO:0051548	biolink:NamedThing	negative regulation of keratinocyte migration	Any process that stops, prevents, or reduces the frequency, rate or extent of keratinocyte migration.	tmpzr1t_l9r_go_relaxed.owl	down regulation of keratinocyte migration|downregulation of keratinocyte migration|down-regulation of keratinocyte migration|inhibition of keratinocyte migration													biological_process											owl:Class	
GO:1900839	biolink:NamedThing	positive regulation of fumigaclavine C biosynthetic process	Any process that activates or increases the frequency, rate or extent of fumigaclavine C biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	upregulation of fumigaclavine C biosynthetic process|up-regulation of fumigaclavine C biosynthetic process|up regulation of fumigaclavine C biosynthetic process							di	2012-06-07T09:36:52Z					biological_process											owl:Class	
GO:0006175	biolink:NamedThing	dATP biosynthetic process	The chemical reactions and pathways resulting in the formation of dATP, deoxyadenosine triphosphate (2'-deoxyadenosine 5'-triphosphate).	tmpzr1t_l9r_go_relaxed.owl	dATP biosynthesis|dATP anabolism|dATP synthesis|dATP formation													biological_process											owl:Class	
GO:0048065	biolink:NamedThing	male courtship behavior, veined wing extension	The process during courtship where the male insect extends his wings. An example of this process is found in Drosophila melanogaster.	tmpzr1t_l9r_go_relaxed.owl	male courtship behaviour, wing extension|male courtship behavior, wing extension|male courtship behaviour, veined wing extension													biological_process											owl:Class	
GO:0006809	biolink:NamedThing	nitric oxide biosynthetic process	The chemical reactions and pathways resulting in the formation of nitric oxide, nitrogen monoxide (NO), a colorless gas only slightly soluble in water.	tmpzr1t_l9r_go_relaxed.owl	nitric oxide formation|nitric oxide biosynthesis|nitric oxide synthesis|nitric oxide anabolism													biological_process											owl:Class	
GO:0004934	biolink:NamedThing	mating-type alpha-factor pheromone receptor activity	Combining with the mating-type alpha-factor pheromone to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	class D G protein coupled receptor activity|class D G-protein-coupled receptor activity|class D GPCR activity|class D G-protein coupled receptor activity													molecular_function											owl:Class	
GO:0030989	biolink:NamedThing	dynein-driven meiotic oscillatory nuclear movement	Oscillatory movement of the nucleus involved in meiosis I. This oscillatory movement is led by an astral microtubule array emanating from the spindle pole body, and driven by the microtubule motor cytoplasmic dynein.	tmpzr1t_l9r_go_relaxed.owl	horsetail nuclear movement|HNM|horsetail movement					Dynein-driven meiotic oscillatory nuclear movement precedes meiotic recombination.								biological_process											owl:Class	
GO:0004449	biolink:NamedThing	isocitrate dehydrogenase (NAD+) activity	Catalysis of the reaction: isocitrate + NAD+ = 2-oxoglutarate + CO2 + NADH + H+.	tmpzr1t_l9r_go_relaxed.owl	nicotinamide adenine dinucleotide isocitrate dehydrogenase activity|NAD dependent isocitrate dehydrogenase activity|NAD-linked isocitrate dehydrogenase activity|NAD isocitrate dehydrogenase activity|isocitrate dehydrogenase (NAD) activity|isocitrate:NAD+ oxidoreductase (decarboxylating)|NAD-specific isocitrate dehydrogenase activity|NAD isocitric dehydrogenase activity				MetaCyc:ISOCITRATE-DEHYDROGENASE-NAD+-RXN|EC:1.1.1.41|Reactome:R-HSA-70967|RHEA:23632									molecular_function											owl:Class	
GO:0004448	biolink:NamedThing	isocitrate dehydrogenase activity	Catalysis of the reaction: isocitrate + acceptor = 2-oxoglutarate + CO2 + reduced acceptor.	tmpzr1t_l9r_go_relaxed.owl	oxalsuccinic decarboxylase activity|IDP1|isocitric dehydrogenase activity|isocitric acid dehydrogenase activity|IDP2|oxalosuccinate decarboxylase activity|IDH activity|IDP3|oxalosuccinate carboxylase activity|beta-ketoglutaric-isocitric carboxylase activity|IDP activity				MetaCyc:ISOCITDEH-RXN									molecular_function											owl:Class	
GO:0031421	biolink:NamedThing	invertasome	A complex formed by a recombinase, a regulatory protein, and the DNA sequences bound by each protein; catalyzes a reversible site-specific recombination reaction that results in the alternate expression of one or more genes in various contexts.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0004974	biolink:NamedThing	leukotriene receptor activity	Combining with a leukotriene to initiate a change in cell activity. Leukotrienes are pharmacologically active substances with a set of three conjugated double bonds; some contain a peptide group based on cysteine.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0033277	biolink:NamedThing	abortive mitotic cell cycle	A cell cycle in which mitosis is begun and progresses normally through the end of anaphase, but not completed, resulting in a cell with increased ploidy.	tmpzr1t_l9r_go_relaxed.owl	abortive mitosis					Note that this term should be used only for abortive mitotic events that occur normally, e.g. during megakaryocyte differentiation; it should not be used for incomplete mitosis resulting from mutation or other abnormal occurrences. Note that this term should not be confused with 'endomitotic cell cycle ; GO:0007113', which describes a process in which no mitotic spindle forms.								biological_process											owl:Class	
GO:0047728	biolink:NamedThing	carnitine 3-dehydrogenase activity	Catalysis of the reaction: carnitine + NAD(+) = 3-dehydrocarnitine + H(+) + NADH.	tmpzr1t_l9r_go_relaxed.owl	carnitine:NAD+ 3-oxidoreductase activity				KEGG_REACTION:R02395|RHEA:19265|EC:1.1.1.108|MetaCyc:CARNITINE-3-DEHYDROGENASE-RXN									molecular_function											owl:Class	
GO:0018597	biolink:NamedThing	ammonia monooxygenase activity	Catalysis of the oxidation of alkanes (up to C8) to alcohols and alkenes (up to C5) to epoxides and alcohols in the presence of ammonium ions.	tmpzr1t_l9r_go_relaxed.owl					EC:1.14.99.39|RHEA:27341|UM-BBD_enzymeID:e0061									molecular_function											owl:Class	
GO:0047294	biolink:NamedThing	phosphoglycerol geranylgeranyltransferase activity	Catalysis of the reaction: sn-glycerol 1-phosphate + all-trans-geranylgeranyl diphosphate = sn-3-O-(geranylgeranyl)glycerol 1-phosphate + diphosphate.	tmpzr1t_l9r_go_relaxed.owl	geranylgeranyl-transferase activity|geranylgeranyl diphosphate:sn-glyceryl phosphate geranylgeranyltransferase activity|glycerol phosphate geranylgeranyltransferase activity				RHEA:23404|MetaCyc:2.5.1.41-RXN|KEGG_REACTION:R04158|EC:2.5.1.41									molecular_function											owl:Class	
GO:1903965	biolink:NamedThing	monounsaturated fatty acid catabolic process	The chemical reactions and pathways resulting in the breakdown of monounsaturated fatty acid.	tmpzr1t_l9r_go_relaxed.owl	monounsaturated fatty acid degradation|monounsaturated fatty acid breakdown|monounsaturated fatty acid catabolism							pr	2015-02-25T20:35:58Z					biological_process											owl:Class	
GO:0097640	biolink:NamedThing	L-ornithine import across plasma membrane	The directed movement of L-ornithine from outside of a cell, across the plasma membrane and into the cytosol.	tmpzr1t_l9r_go_relaxed.owl	L-ornithine import into cell							pr	2014-09-03T09:48:14Z			GO:1903411		biological_process											owl:Class	
GO:1900860	biolink:NamedThing	positive regulation of brevianamide F biosynthetic process	Any process that activates or increases the frequency, rate or extent of brevianamide F biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	up regulation of brevianamide F biosynthetic process|up-regulation of brevianamide F biosynthetic process|upregulation of brevianamide F biosynthetic process							di	2012-06-07T09:53:25Z					biological_process											owl:Class	
GO:0039634	biolink:NamedThing	killing by virus of host cell during superinfection exclusion	The viral-killing of a host cell by a pre-existing virus in response to a subsequent infection of the host cell by second virus.	tmpzr1t_l9r_go_relaxed.owl	Rex exclusion|killing by virus of host cells involved in superinfection exclusion|killing by virus of host cells during superinfection exclusion							bf	2012-08-10T14:46:03Z					biological_process											owl:Class	
GO:0102180	biolink:NamedThing	4alpha-hydroxymethyl-stigmasta-7,24(241)-dien-3beta-ol-methyl oxidase activity	Catalysis of the reaction: 4alpha-hydroxymethyl-stigmasta-7,24(241)-dien-3beta-ol + NADH + O2 + H+ <=> 4alpha-formyl-stigmasta-7,24(241)-dien-3beta-ol + NAD + 2 H2O.	tmpzr1t_l9r_go_relaxed.owl					RHEA:59036|MetaCyc:RXN-11936									molecular_function											owl:Class	
GO:0033806	biolink:NamedThing	fluorothreonine transaldolase activity	Catalysis of the reaction: L-threonine + fluoroacetaldehyde = acetaldehyde + 4-fluoro-L-threonine.	tmpzr1t_l9r_go_relaxed.owl	fluoroacetaldehyde:L-threonine aldehydetransferase activity				RHEA:11748|EC:2.2.1.8									molecular_function											owl:Class	
GO:0009253	biolink:NamedThing	peptidoglycan catabolic process	The chemical reactions and pathways resulting in the breakdown of peptidoglycans, any of a class of glycoconjugates found in bacterial cell walls.	tmpzr1t_l9r_go_relaxed.owl	peptidoglycan degradation|peptidoglycan breakdown|murein catabolic process|murein catabolism|peptidoglycan catabolism											GO:0009286		biological_process											owl:Class	
GO:0042985	biolink:NamedThing	negative regulation of amyloid precursor protein biosynthetic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of amyloid precursor protein (APP), the precursor of amyloid-beta.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of amyloid precursor protein biosynthesis|negative regulation of amyloid precursor protein anabolism|down-regulation of amyloid precursor protein biosynthetic process|inhibition of amyloid precursor protein biosynthetic process|downregulation of amyloid precursor protein biosynthetic process|negative regulation of amyloid precursor protein synthesis|negative regulation of APP biosynthesis|negative regulation of APP biosynthetic process|down regulation of amyloid precursor protein biosynthetic process|negative regulation of amyloid precursor protein formation													biological_process											owl:Class	
GO:0002729	biolink:NamedThing	positive regulation of natural killer cell cytokine production	Any process that activates or increases the frequency, rate, or extent of natural killer cell cytokine production.	tmpzr1t_l9r_go_relaxed.owl	up regulation of natural killer cell cytokine production|positive regulation of NK cell cytokine production|upregulation of natural killer cell cytokine production|stimulation of natural killer cell cytokine production|activation of natural killer cell cytokine production|up-regulation of natural killer cell cytokine production													biological_process											owl:Class	
GO:0034299	biolink:NamedThing	reproductive blastospore formation	The formation of a spore following the marked enlargement of part of a cell before separation by a septum. Blastospores are a type of asexual spore found in some fungi, most notably the class Glomeromycota.	tmpzr1t_l9r_go_relaxed.owl	blastoconidium formation					Note that this term should not be confused with the usage of 'blastospore' to mean any yeast-form fungal cell, as in Candida species.								biological_process											owl:Class	
GO:0043838	biolink:NamedThing	phosphatidylethanolamine:Kdo2-lipid A phosphoethanolamine transferase activity	Catalysis of the reaction: Kdo2-lipid A + phosphatidylethanolamine = phosphoethanolamine-Kdo2-lipid A + diacylglycerol.	tmpzr1t_l9r_go_relaxed.owl	phosphoethanolamine transferase|EptB					Note that Kdo is an abbreviation for 3-deoxy-D-manno-oct-2-ulosonic acid.								molecular_function											owl:Class	
GO:0047346	biolink:NamedThing	aldose-1-phosphate adenylyltransferase activity	Catalysis of the reaction: aldose 1-phosphate + ADP = phosphate + ADP-aldose.	tmpzr1t_l9r_go_relaxed.owl	ADP:alpha-D-aldose-1-phosphate adenylyltransferase activity|ADP-aldose phosphorylase activity|ADPaldose phosphorylase activity|adenosine diphosphosugar phosphorylase activity|ADP sugar phosphorylase activity|sugar-1-phosphate adenylyltransferase activity|adenosine diphosphate glucose:orthophosphate adenylyltransferase activity|ADP-sugar phosphorylase activity|ADP:aldose-1-phosphate adenylyltransferase activity				MetaCyc:2.7.7.36-RXN|EC:2.7.7.36									molecular_function											owl:Class	
GO:0098758	biolink:NamedThing	response to interleukin-8	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-8 stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to IL-8													biological_process											owl:Class	
GO:0050278	biolink:NamedThing	sedoheptulose-bisphosphatase activity	Catalysis of the reaction: sedoheptulose 1,7-bisphosphate + H2O = sedoheptulose 7-phosphate + phosphate.	tmpzr1t_l9r_go_relaxed.owl	sedoheptulose-1,7-bisphosphatase activity|sedoheptulose diphosphatase activity|sedoheptulose-1,7-bisphosphate 1-phosphohydrolase activity|sedoheptulose 1,7-diphosphatase activity|sedoheptulose bisphosphatase activity|sedoheptulose 1,7-diphosphate phosphatase activity|sedoheptulose 1,7-bisphosphatase activity|SBPase activity				MetaCyc:SEDOHEPTULOSE-BISPHOSPHATASE-RXN|RHEA:17461|EC:3.1.3.37									molecular_function											owl:Class	
GO:1904430	biolink:NamedThing	negative regulation of t-circle formation	Any process that stops, prevents or reduces the frequency, rate or extent of t-circle formation.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of telomeric circle formation|down regulation of t-circle formation|downregulation of telomeric circle formation|inhibition of telomeric circle formation|inhibition of t-circle formation|down-regulation of t-circle formation|down regulation of telomeric circle formation|down-regulation of telomeric circle formation|downregulation of t-circle formation							nc	2015-07-03T15:15:52Z					biological_process											owl:Class	
GO:0008312	biolink:NamedThing	7S RNA binding	Binding to a 7S RNA, the RNA component of the signal recognition particle (SRP).	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0046358	biolink:NamedThing	butyrate biosynthetic process	The chemical reactions and pathways resulting in the formation of butyrate, the anion of butyric acid.	tmpzr1t_l9r_go_relaxed.owl	butanoic acid biosynthetic process|butanoic acid formation|butanoic acid synthesis|butyrate biosynthesis|butyrate anabolism|butyrate synthesis|butanoic acid biosynthesis|butanoic acid anabolism|butyrate formation											GO:0043439		biological_process											owl:Class	
GO:0070477	biolink:NamedThing	endospore core	An intracellular part that represents the innermost portion of an endospore; the endospore core is dehydrated, enriched in dipicolinic acid and divalent cations, and metabolically inactive.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0071342	biolink:NamedThing	regulation of establishment of actomyosin contractile ring localization	Any process that modulates the frequency, rate or extent of the process in which a contractile ring is assembled in a specific location that contributes to cytokinesis during cell cycle.	tmpzr1t_l9r_go_relaxed.owl	regulation of establishment of contractile ring localization involved in cytokinesis during cell cycle|regulation of establishment of contractile ring localisation involved in cell cycle cytokinesis|regulation of establishment of contractile ring localization involved in cell cycle cytokinesis							mah	2009-12-11T01:22:11Z					biological_process											owl:Class	
GO:0022841	biolink:NamedThing	potassium ion leak channel activity	Enables the transport of a potassium ion across a membrane via a narrow pore channel that is open even in an unstimulated or 'resting' state.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0022840	biolink:NamedThing	leak channel activity	Enables the transport of a solute across a membrane via a narrow pore channel that is open even in an unstimulated or 'resting' state.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0050606	biolink:NamedThing	4-carboxy-2-hydroxymuconate semialdehyde hemiacetal dehydrogenase activity	Catalysis of the reaction: 4-carboxy-2-hydroxymuconate semialdehyde hemiacetal + NADP(+) = 2-oxo-2H-pyran-4,6-dicarboxylate + H(+) + NADPH.	tmpzr1t_l9r_go_relaxed.owl	alpha-hydroxy-gamma-carboxymuconic epsilon-semialdehyde dehydrogenase activity|4-carboxy-2-hydroxy-cis,cis-muconate-6-semialdehyde:NADP(+) oxidoreductase activity|4-carboxy-2-hydroxymuconate-6-semialdehyde dehydrogenase activity|2-hydroxy-4-carboxymuconate 6-semialdehyde dehydrogenase activity				EC:1.1.1.312|RHEA:29587|KEGG_REACTION:R04279|MetaCyc:1.2.1.45-RXN									molecular_function											owl:Class	
GO:0018396	biolink:NamedThing	peptidyl-lysine hydroxylation to 4-hydroxy-L-lysine	The hydroxylation of peptidyl-lysine to peptidyl-4-hydroxy-L-lysine.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0235									biological_process											owl:Class	
GO:0070138	biolink:NamedThing	ubiquitin-like protein-specific isopeptidase activity	Catalysis of the hydrolysis of an isopeptide bond between a small protein such as ubiquitin or a ubiquitin-like protein (e.g. APG8, ISG15, NEDD8, SUMO) and a protein to which the small protein has been conjugated.	tmpzr1t_l9r_go_relaxed.owl	small conjugating protein-specific isopeptidase activity													molecular_function											owl:Class	
GO:0051967	biolink:NamedThing	negative regulation of synaptic transmission, glutamatergic	Any process that stops, prevents, or reduces the frequency, rate or extent of glutamatergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glutamate.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of synaptic transmission, glutamatergic|down regulation of synaptic transmission, glutamatergic|inhibition of synaptic transmission, glutamatergic|downregulation of synaptic transmission, glutamatergic													biological_process											owl:Class	
GO:0044580	biolink:NamedThing	butyryl-CoA catabolic process	The chemical reactions a resulting in the resulting in the breakdown of butyryl-CoA.	tmpzr1t_l9r_go_relaxed.owl	butyryl-CoA catabolism							jl	2012-04-19T04:28:46Z					biological_process											owl:Class	
GO:0032095	biolink:NamedThing	regulation of response to food	Any process that modulates the frequency, rate or extent of a response to a food stimulus.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1990428	biolink:NamedThing	miRNA transport	The directed movement of microRNA (miRNA) into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	microRNA transport							jl	2014-07-29T14:03:46Z					biological_process											owl:Class	
GO:1904542	biolink:NamedThing	regulation of free ubiquitin chain polymerization	Any process that modulates the frequency, rate or extent of free ubiquitin chain polymerization.	tmpzr1t_l9r_go_relaxed.owl						An example of this is PARK2 in human (UniProt symbol O60260) in PMID:24660806 (inferred from mutant phenotype).		pad	2015-08-11T11:44:53Z					biological_process											owl:Class	
GO:0071021	biolink:NamedThing	U2-type post-spliceosomal complex	A spliceosomal complex that is formed following the second splicing event and contains the spliced product, the excised intron, and three snRNPs, U5, U2 and U6.	tmpzr1t_l9r_go_relaxed.owl	major post-spliceosomal complex|mammalian U2-type spliceosomal complex C2|yeast U2-type spliceosomal complex A2-3|GT-AG post-spliceosomal complex							mah	2009-07-30T12:00:35Z					cellular_component											owl:Class	
GO:0071020	biolink:NamedThing	post-spliceosomal complex	A spliceosomal complex that is formed following the second splicing event and contains the spliced product, the excised intron, and three snRNPs, including U5.	tmpzr1t_l9r_go_relaxed.owl	mammalian spliceosomal complex C2|yeast spliceosomal complex A2-3							mah	2009-07-30T12:00:35Z					cellular_component											owl:Class	
GO:1903137	biolink:NamedThing	regulation of cell wall integrity MAPK cascade	Any process that modulates the frequency, rate or extent of MAPK cascade involved in cell wall organization or biogenesis.	tmpzr1t_l9r_go_relaxed.owl	regulation of MAPK cascade involved in cell wall organization or biogenesis|regulation of cell integrity MAPK pathway|regulation of PMK1-MAPK signal transduction pathway|regulation of Pmk1 MAPK cell integrity signaling|regulation of Slt2 cascade|regulation of MAPKKK cascade involved in cell wall biogenesis|regulation of Pmk1 mitogen-activated protein kinase (MAPK) cell integrity pathway|regulation of Mpk1 cascade|regulation of MAPK cascade involved in cell wall biogenesis|regulation of cell wall biogenesis, MAPKKK cascade	https://github.com/geneontology/go-ontology/issues/20131						mah	2014-07-01T10:21:53Z					biological_process											owl:Class	
GO:0090083	biolink:NamedThing	regulation of inclusion body assembly	Any process that modulates the rate, frequency, or extent of inclusion body assembly. Inclusion body assembly is the aggregation, arrangement and bonding together of a set of components to form an inclusion body.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-10-23T11:07:22Z					biological_process											owl:Class	
GO:0043980	biolink:NamedThing	histone H2B-K12 acetylation	The modification of histone H2B by the addition of an acetyl group to a lysine residue at position 12 of the histone.	tmpzr1t_l9r_go_relaxed.owl	histone H2B acetylation at K12													biological_process											owl:Class	
GO:0102133	biolink:NamedThing	limonene hydroxylase activity	Catalysis of the reaction: (4R)-limonene + O2 + NADH + H+ <=> (4R)-perillyl alcohol + NAD + H2O.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-11493									molecular_function											owl:Class	
GO:0018780	biolink:NamedThing	dichloroacetate halidohydrolase activity	Catalysis of the reaction: dichloroacetate + H2O = 2 HCl + glyoxylate.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0383									molecular_function											owl:Class	
GO:0071467	biolink:NamedThing	cellular response to pH	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus. pH is a measure of the acidity or basicity of an aqueous solution.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-12-18T11:41:54Z					biological_process											owl:Class	
GO:0060234	biolink:NamedThing	neuroblast delamination	The negative regulation of cell adhesion process in which a neuroblast splits off of a neurectodermal sheet.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0046624	biolink:NamedThing	sphingolipid transporter activity	Enables the directed movement of sphingolipids into, out of or within a cell, or between cells. Sphingolipids are a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid).	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-9695890									molecular_function											owl:Class	
GO:0047415	biolink:NamedThing	D-benzoylarginine-4-nitroanilide amidase activity	Catalysis of the reaction: N(2)-benzoyl-D-arginine-4-nitroanilide + H(2)O = 4-nitroaniline + N(2)-benzoyl-D-arginine + H(+).	tmpzr1t_l9r_go_relaxed.owl	N-benzoyl-D-arginine-4-nitroanilide amidohydrolase activity|D-BAPA-ase activity|benzoyl-D-arginine arylamidase activity				KEGG_REACTION:R04113|EC:3.5.1.72|RHEA:14421|MetaCyc:3.5.1.72-RXN									molecular_function											owl:Class	
GO:0052804	biolink:NamedThing	nitroimidazole catabolic process	The chemical reactions and pathways resulting in the breakdown of nitroimidazoles, imidazole derivatives with a nitro group attached to one ring.	tmpzr1t_l9r_go_relaxed.owl	nitroimidazole degradation|nitroimidazole catabolism|nitroimidazole breakdown													biological_process											owl:Class	
GO:0019447	biolink:NamedThing	D-cysteine catabolic process	The chemical reactions and pathways resulting in the breakdown of D-cysteine, (S)-2-amino-3-mercaptopropanoic acid, which occurs naturally in firefly luciferin.	tmpzr1t_l9r_go_relaxed.owl	D-cysteine catabolism|D-cysteine breakdown|D-cysteine degradation													biological_process											owl:Class	
GO:0033235	biolink:NamedThing	positive regulation of protein sumoylation	Any process that activates or increases the frequency, rate or extent of the addition of SUMO groups to a protein.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of sumoylation													biological_process											owl:Class	
GO:0004865	biolink:NamedThing	protein serine/threonine phosphatase inhibitor activity	Binds to and stops, prevents or reduces the activity of a serine/threonine protein phosphatase, an enzyme that catalyzes the reaction: protein serine/threonine phosphate + H2O = protein serine/threonine + phosphate.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1904239	biolink:NamedThing	regulation of VCP-NPL4-UFD1 AAA ATPase complex assembly	Any process that modulates the frequency, rate or extent of VCP-NPL4-UFD1 AAA ATPase complex assembly.	tmpzr1t_l9r_go_relaxed.owl	regulation of VCP-NPL4-UFD1 AAA ATPase complex formation|regulation of p97-Ufd1-Npl4 complex assembly|regulation of p97-Ufd1-Npl4 complex formation|regulation of Cdc48p-Npl4p-Ufd1p AAA ATPase complex assembly|regulation of Cdc48p-Npl4p-Ufd1p AAA ATPase complex formation							bf	2015-05-18T09:50:21Z					biological_process											owl:Class	
GO:0010590	biolink:NamedThing	regulation of septum digestion after cytokinesis	Any process that modulates the rate, frequency or extent of the process of physically separating the septal cell wall material by enzymatic digestion, that occurs after daughter cells are separated by cytokinesis.	tmpzr1t_l9r_go_relaxed.owl	regulation of mitotic cytokinetic cell separation|regulation of cell separation following cytokinesis|regulation of cell separation after cytokinesis											GO:1902467|GO:2001041		biological_process											owl:Class	
GO:0102083	biolink:NamedThing	7,8-dihydromonapterin aldolase activity	Catalysis of the reaction: 7,8-dihydromonapterin <=> glycolaldehyde + 2-amino-6-(hydroxymethyl)-7,8-dihydropteridin-4-ol.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-10857									molecular_function											owl:Class	
GO:0032468	biolink:NamedThing	Golgi calcium ion homeostasis	Any process involved in the maintenance of an internal steady state of calcium ions within the Golgi apparatus of a cell or between the Golgi and its surroundings.	tmpzr1t_l9r_go_relaxed.owl	regulation of calcium ion concentration in Golgi|Golgi calcium ion concentration regulation|regulation of Golgi calcium ion concentration|calcium ion homeostasis in Golgi													biological_process											owl:Class	
GO:0015860	biolink:NamedThing	purine nucleoside transmembrane transport	The process in which a purine nucleoside is transported across a membrane. A purine nucleoside is a purine base covalently bonded to a ribose or deoxyribose sugar.	tmpzr1t_l9r_go_relaxed.owl	purine nucleoside membrane transport|purine nucleoside transport					Note that this term is not intended for use in annotating lateral movement within membranes.						GO:0035427		biological_process											owl:Class	
GO:0110089	biolink:NamedThing	regulation of hippocampal neuron apoptotic process	Any process that modulates the occurrence or rate of cell death by apoptotic process in hippocampal neurons.	tmpzr1t_l9r_go_relaxed.owl								kmv	2018-02-13T21:18:29Z					biological_process											owl:Class	
GO:1902725	biolink:NamedThing	negative regulation of satellite cell differentiation	Any process that stops, prevents or reduces the frequency, rate or extent of satellite cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	inhibition of satellite cell differentiation|down-regulation of satellite cell differentiation|down regulation of satellite cell differentiation|downregulation of satellite cell differentiation							mr	2014-02-24T16:10:05Z					biological_process											owl:Class	
GO:0061232	biolink:NamedThing	mesonephric glomerular epithelium development	The process whose specific outcome is the progression of the mesonephric glomerular epithelium over time, from its formation to the mature structure. The mesonephric glomerular epithelium is an epithelial tissue that covers the outer surfaces of the glomerulus in the mesonephros. The mesonephric glomerular epithelium consists of both parietal and visceral epithelium. Mesonephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. A mesonephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the mesonephros.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-08-19T02:49:46Z					biological_process											owl:Class	
GO:0060846	biolink:NamedThing	blood vessel endothelial cell fate commitment	The commitment of a cell to a blood vessel endothelial cell fate and its capacity to differentiate into a blood vessel endothelial cell.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-08-12T10:56:14Z					biological_process											owl:Class	
GO:1990883	biolink:NamedThing	rRNA cytidine N-acetyltransferase activity	Catalysis of the reaction: acetyl-CoA + cytidine = CoA + N4-acetylcytidine. The cytidine is within the polynucleotide chain of an rRNA.	tmpzr1t_l9r_go_relaxed.owl								al	2015-10-28T13:27:35Z					molecular_function											owl:Class	
GO:2001147	biolink:NamedThing	camalexin binding	Binding to camalexin.	tmpzr1t_l9r_go_relaxed.owl	3-(1,3-thiazol-2-yl)-1H-indole binding							tb	2011-10-19T10:54:19Z					molecular_function											owl:Class	
GO:0005848	biolink:NamedThing	mRNA cleavage stimulating factor complex	A protein complex required for mRNA cleavage but not for poly(A) addition.	tmpzr1t_l9r_go_relaxed.owl	CstF complex|cleavage stimulation factor activity													cellular_component											owl:Class	
GO:0031822	biolink:NamedThing	type 1B serotonin receptor binding	Binding to a type 1B serotonin receptor.	tmpzr1t_l9r_go_relaxed.owl	5-hydroxytryptamine 1B receptor binding|type 1B serotonin receptor ligand													molecular_function											owl:Class	
GO:0018675	biolink:NamedThing	(S)-limonene 6-monooxygenase activity	Catalysis of the reaction: (-)-limonene + NADPH + H+ + O2 = (-)-trans-carveol + NADP+ + H2O.	tmpzr1t_l9r_go_relaxed.owl	(-)-limonene 6-monooxygenase activity|(-)-limonene,NADPH:oxygen oxidoreductase (6-hydroxylating) activity|(S)-limonene,NADPH:oxygen oxidoreductase (6-hydroxylating)|limonene 6-hydroxylase activity|(-)-limonene 6-hydroxylase activity				UM-BBD_reactionID:r0713|RHEA:17945|EC:1.14.14.51|MetaCyc:--LIMONENE-6-MONOOXYGENASE-RXN									molecular_function											owl:Class	
GO:0070056	biolink:NamedThing	prospore membrane leading edge	The region of the prospore membrane that extends to surround the spore nucleus; coated with specific proteins that are thought to play a role in prospore membrane organization.	tmpzr1t_l9r_go_relaxed.owl	forespore membrane leading edge													cellular_component											owl:Class	
GO:0098725	biolink:NamedThing	symmetric cell division	Cell division in which both daughter cells are of the same type.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0004381	biolink:NamedThing	fucosylgalactoside 3-alpha-galactosyltransferase activity	Catalysis of the reaction: UDP-galactose + glycoprotein-alpha-L-fucosyl-(1,2)-D-galactose = UDP + glycoprotein-alpha-D-galactosyl-(1,3)-(alpha-L-fucosyl-(1,2))-D-galactose.	tmpzr1t_l9r_go_relaxed.owl	UDP-galactose:alpha-L-fucosyl-(1,2)-D-galactoside 3-alpha-D-galactosyltransferase activity|UDPgalactose:alpha-L-fucosyl-(1,2)-D-galactoside 3-alpha-D-galactosyltransferase activity|UDPgalactose:alpha-L-fucosyl-(1->2)-D-galactoside 3-alpha-D-galactosyltransferase activity|UDP-galactose:alpha-L-fucosyl-(1->2)-D-galactoside 3-alpha-D-galactosyltransferase activity|histo-blood substance B-dependent galactosyltransferase activity|histo-blood substance beta-dependent galactosyltransferase activity|histo-blood group B transferase activity|glycoprotein-fucosylgalactoside alpha-galactosyltransferase activity|blood-group substance beta-dependent galactosyltransferase activity|[blood group substance] alpha-galactosyltransferase activity|B transferase activity|UDPgalactose:glycoprotein-alpha-L-fucosyl-(1,2)-D-galactose 3-alpha-D-galactosyltransferase activity|fucosylglycoprotein 3-alpha-galactosyltransferase activity|blood-group substance B-dependent galactosyltransferase activity|UDPgalactose:O-alpha-L-fucosyl(1,2)D-galactose alpha-D-galactosyltransferase activity|UDPgalactose:O-alpha-L-fucosyl(1->2)D-galactose alpha-D-galactosyltransferase activity				Reactome:R-HSA-9034053|MetaCyc:2.4.1.37-RXN|Reactome:R-HSA-9033961|RHEA:14349|EC:2.4.1.37									molecular_function											owl:Class	
GO:0015764	biolink:NamedThing	N-acetylglucosamine transport	The directed movement of N-acetylglucosamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0031318	biolink:NamedThing	detection of folic acid	The series of events in which a folic acid stimulus is received by a cell and converted into a molecular signal.	tmpzr1t_l9r_go_relaxed.owl	folate detection|detection of folate|folate sensing|folic acid sensing|folic acid detection													biological_process											owl:Class	
GO:0009594	biolink:NamedThing	detection of nutrient	The series of events in which a nutrient stimulus is received by a cell and converted into a molecular signal.	tmpzr1t_l9r_go_relaxed.owl	nutrient sensing|detection of nutrients|perception of nutrients													biological_process											owl:Class	
GO:0102179	biolink:NamedThing	24-ethylidenelophenol 4alpha-methyl oxidase activity	Catalysis of the reaction: 24-ethylidenelophenol + NADH + O2 + H+ <=> 4alpha-hydroxymethyl-stigmasta-7,24(241)-dien-3beta-ol + NAD + H2O.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-11935|RHEA:59032									molecular_function											owl:Class	
GO:0007182	biolink:NamedThing	common-partner SMAD protein phosphorylation	The process of introducing a phosphate group on to a common-partner SMAD protein. A common partner SMAD protein binds to pathway-restricted SMAD proteins forming a complex that translocates to the nucleus.	tmpzr1t_l9r_go_relaxed.owl	common partner SMAD protein phosphorylation|common-mediator SMAD protein phosphorylation|common mediator SMAD protein phosphorylation|co-SMAD protein phosphorylation													biological_process											owl:Class	
GO:0007437	biolink:NamedThing	adult salivary gland morphogenesis	The process in which the anatomical structures of the adult salivary gland are generated and organized.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0032830	biolink:NamedThing	negative regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of differentiation of CD4-positive, CD25-positive, alpha-beta regulatory T cells.	tmpzr1t_l9r_go_relaxed.owl	inhibition of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation|down-regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation|negative regulation of CD4-positive, CD25-positive, alpha-beta regulatory T-cell differentiation|negative regulation of CD4-positive, CD25-positive, alpha-beta regulatory T lymphocyte differentiation|negative regulation of CD4-positive, CD25-positive, alpha-beta regulatory T-lymphocyte differentiation|negative regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell development|down regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation|downregulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation					Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.								biological_process											owl:Class	
GO:0050104	biolink:NamedThing	L-gulonate 3-dehydrogenase activity	Catalysis of the reaction: L-gulonate + NAD(+) = 3-dehydro-L-gulonate + H(+) + NADH.	tmpzr1t_l9r_go_relaxed.owl	L-gulonic acid dehydrogenase activity|L-3-aldonic dehydrogenase activity|L-beta-hydroxy-acid-NAD-oxidoreductase activity|L-3-aldonate dehydrogenase activity|L-3-hydroxyacid dehydrogenase activity|L-gulonate:NAD+ 3-oxidoreductase activity|L-beta-hydroxyacid dehydrogenase activity				KEGG_REACTION:R02640|MetaCyc:L-GULONATE-3-DEHYDROGENASE-RXN|Reactome:R-HSA-5661290|RHEA:12889|EC:1.1.1.45									molecular_function											owl:Class	
GO:0018630	biolink:NamedThing	3,5-xylenol methylhydroxylase activity	Catalysis of the reaction: 3-hydroxytoluene + NADH + O2 = NAD+ + OH- + 3-hydroxybenzyl alcohol.	tmpzr1t_l9r_go_relaxed.owl					EC:1.14.13.-|MetaCyc:3-5-XYLENOL-METHYLHYDROXYLASE-RXN|UM-BBD_reactionID:r0081									molecular_function											owl:Class	
GO:0102746	biolink:NamedThing	tetrahydrogeranylgeranyl-PP reductase activity	Catalysis of the reaction: H+ + tetrahydrogeranylgeranyl-PP + NADPH = (E)-3,7,11,15-tetramethylhexadec-2-en-1-yl diphosphate + NADP.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-7660									molecular_function											owl:Class	
GO:0050194	biolink:NamedThing	phosphonoacetaldehyde hydrolase activity	Catalysis of the reaction: H(2)O + phosphonoacetaldehyde = acetaldehyde + H(+) + phosphate.	tmpzr1t_l9r_go_relaxed.owl	2-oxoethylphosphonate phosphonohydrolase activity|2-phosphonoacetylaldehyde phosphonohydrolase activity|phosphonatase activity|phosphonoacetylaldehyde phosphonohydrolase activity				KEGG_REACTION:R00747|RHEA:18905|MetaCyc:PHOSPHONOACETALDEHYDE-HYDROLASE-RXN|EC:3.11.1.1									molecular_function											owl:Class	
GO:0033399	biolink:NamedThing	cis-zeatin metabolic process	The chemical reactions and pathways involving cis-zeatin, (2Z)-2-methyl-4-(9H-purin-6-ylamino)but-2-en-1-ol.	tmpzr1t_l9r_go_relaxed.owl	cis-zeatin metabolism													biological_process											owl:Class	
GO:0000378	biolink:NamedThing	RNA exon ligation	The RNA metabolic process that joins two exons, each of which has free ends that were generated by endonucleolytic cleavages, by a ligation reaction.	tmpzr1t_l9r_go_relaxed.owl						Note that this is not a part of spliceosomal RNA splicing.								biological_process											owl:Class	
GO:0019390	biolink:NamedThing	glucuronoside biosynthetic process	The chemical reactions and pathways resulting in the formation of glucuronosides, compound composed of a hydroxy compound linked to a glucuronate residue.	tmpzr1t_l9r_go_relaxed.owl	glucuronoside anabolism|glucuronoside biosynthesis|glucuronoside synthesis|glucuronide biosynthetic process|glucuronide biosynthesis|glucuronoside formation													biological_process											owl:Class	
GO:0018660	biolink:NamedThing	4-hydroxyphenylacetate,NADH:oxygen oxidoreductase (3-hydroxylating) activity	Catalysis of the reaction: 4-hydroxyphenylacetate + NADH + H+ + O2 = 3,4-dihydroxyphenylacetate + NAD+ + H2O.	tmpzr1t_l9r_go_relaxed.owl	p-hydroxyphenylacetate hydroxylase activity|4-hydroxyphenylacetate 3-hydroxylase activity|p-hydroxyphenylacetate 3-hydroxylase activity|4-hydroxyphenylacetate 3-monooxygenase activity|4 HPA 3-hydroxylase activity				RHEA:16681|KEGG_REACTION:R02698|EC:1.14.14.9									molecular_function											owl:Class	
GO:0052780	biolink:NamedThing	chitobiose metabolic process	The chemical reactions and pathways involving chitobioses, a family of compounds derived from chitin and based on the structure of D-glucosaminyl-(1->4)-D-glucosamine.	tmpzr1t_l9r_go_relaxed.owl								ai	2011-10-03T08:48:09Z					biological_process											owl:Class	
GO:0061222	biolink:NamedThing	mesonephric mesenchymal cell proliferation involved in mesonephros development	The multiplication or reproduction of cells, resulting in the expansion of a mesonephric mesenchymal cell population.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-08-19T01:20:14Z					biological_process											owl:Class	
GO:0062068	biolink:NamedThing	chloroplast photosystem II binding	Binding to a chloroplast photosystem II.	tmpzr1t_l9r_go_relaxed.owl								dph	2018-08-31T14:09:17Z					molecular_function											owl:Class	
GO:0070737	biolink:NamedThing	protein-glycine ligase activity, elongating	Catalysis of the posttranslational transfer of one or more glycine residues to a glycine residue covalently attached to the gamma-carboxyl group of a glutamate residue on a target protein, resulting in the elongation of a polyglycine side chain.	tmpzr1t_l9r_go_relaxed.owl	protein glycylase activity, elongating							mah	2009-06-19T02:00:21Z					molecular_function											owl:Class	
GO:0030629	biolink:NamedThing	U6 snRNA 3'-end binding	Binding to a U6 small nuclear RNA (U6 snRNA) at the 3' end.	tmpzr1t_l9r_go_relaxed.owl	U6 snRNA 3' end binding					Note that this term may be useful for annotating small nuclear RNAs (snRNAs).								molecular_function											owl:Class	
GO:0017070	biolink:NamedThing	U6 snRNA binding	Binding to a U6 small nuclear RNA (U6 snRNA).	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1905204	biolink:NamedThing	negative regulation of connective tissue replacement	Any process that stops, prevents or reduces the frequency, rate or extent of connective tissue replacement.	tmpzr1t_l9r_go_relaxed.owl	downregulation of connective tissue replacement|inhibition of connective tissue replacement|down-regulation of connective tissue replacement|down regulation of connective tissue replacement							bc	2016-05-17T09:54:27Z					biological_process											owl:Class	
GO:0014734	biolink:NamedThing	skeletal muscle hypertrophy	The enlargement or overgrowth of all or part of an organ due to an increase in size (not length) of individual muscle fibers without cell division. In the case of skeletal muscle cells this happens due to the additional synthesis of sarcomeric proteins and assembly of myofibrils.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0031729	biolink:NamedThing	CCR4 chemokine receptor binding	Binding to a CCR4 chemokine receptor.	tmpzr1t_l9r_go_relaxed.owl	CCR4 chemokine receptor ligand													molecular_function											owl:Class	
GO:0042946	biolink:NamedThing	glucoside transport	The directed movement of glucosides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Glucosides are glycosides in which the sugar group is a glucose residue.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0106333	biolink:NamedThing	subcortical maternal complex	Comprised of at least NLRP5, OOEP, TLE6, and KHDC3/KHDC3L with evidence of additional SCMC-associated proteins that interact with one or multiple members of the core complex.	tmpzr1t_l9r_go_relaxed.owl	SCMC							hjd	2020-10-14T13:49:57Z					cellular_component											owl:Class	
GO:0032556	biolink:NamedThing	pyrimidine deoxyribonucleotide binding	Binding to a pyrimidine deoxyribonucleotide, any compound consisting of a pyrimidine deoxyribonucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the deoxyribose moiety.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0047838	biolink:NamedThing	D-xylose 1-dehydrogenase (NAD) activity	Catalysis of the reaction: D-xylose + NAD+ = D-xylonolactone + NADH.	tmpzr1t_l9r_go_relaxed.owl	NAD-D-xylose dehydrogenase activity|D-xylose:NAD+ 1-oxidoreductase activity|(NAD)-linked D-xylose dehydrogenase activity|NAD-D-xylose|NAD-linked D-xylose dehydrogenase activity|D-xylose dehydrogenase activity				EC:1.1.1.175|MetaCyc:D-XYLOSE-1-DEHYDROGENASE-RXN|RHEA:13861									molecular_function											owl:Class	
GO:0070315	biolink:NamedThing	G1 to G0 transition involved in cell differentiation	A cell cycle arrest process that results in arrest during G1 phase, whereupon the cell enters G0 phase, in the context of cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	G1/G0 transition involved in cell differentiation													biological_process											owl:Class	
GO:0050026	biolink:NamedThing	L-glycol dehydrogenase activity	Catalysis of the reaction: an L-glycol + NAD(P)+ = a 2-hydroxycarbonyl compound + NAD(P)H + H+.	tmpzr1t_l9r_go_relaxed.owl	L-glycol:NAD(P)+ oxidoreductase activity|L-(+)-glycol:NAD(P) oxidoreductase activity|L-glycol:NAD(P) dehydrogenase activity|glycol (nicotinamide adenine dinucleotide (phosphate)) dehydrogenase activity				EC:1.1.1.185|MetaCyc:L-GLYCOL-DEHYDROGENASE-RXN									molecular_function											owl:Class	
GO:0010384	biolink:NamedThing	cell wall proteoglycan metabolic process	The chemical reactions and pathways involving cell wall peptidoglycan, a group of glycoproteins that consist of a core-protein backbone O-glycosylated by one or more complex carbohydrates.	tmpzr1t_l9r_go_relaxed.owl	cell wall proteoglycan metabolism													biological_process											owl:Class	
GO:1903998	biolink:NamedThing	regulation of eating behavior	Any process that modulates the frequency, rate or extent of eating behavior.	tmpzr1t_l9r_go_relaxed.owl	regulation of eating behaviour							sl	2015-03-05T20:40:22Z					biological_process											owl:Class	
GO:0030491	biolink:NamedThing	heteroduplex formation	The formation of a stable duplex DNA that contains one strand from each of the two recombining DNA molecules.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0002937	biolink:NamedThing	tRNA 4-thiouridine biosynthesis	The processes whereby a uridine residue in a tRNA is converted to 4-thiouridine. Typically 4-thiouridine is found at position 8, in many transfer RNAs.	tmpzr1t_l9r_go_relaxed.owl						In E. coli, two genes are involved, nuvA (aka Thi) and NuvC (aka iscS) . NuvA converts the trNA into an unidentified intermediate in an ATP dependent manner. NucC catalyzes the second step, transferring the sulfur from cysteine to an unidentified intermediate. NuvC also participates in thiamine synthesis.		hjd	2012-10-19T15:26:28Z					biological_process											owl:Class	
GO:0005527	biolink:NamedThing	macrolide binding	Binding to a macrolide, any of a large group of structurally related antibiotics produced by Streptomyces species.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0036059	biolink:NamedThing	nephrocyte diaphragm assembly	The aggregation, arrangement and bonding together of a set of components to form a nephrocyte diaphragm, a specialized cell-cell junction found between nephrocytes of the insect kidney.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-12-12T04:38:40Z					biological_process											owl:Class	
GO:0038113	biolink:NamedThing	interleukin-9-mediated signaling pathway	A series of molecular signals initiated by the binding of interleukin-9 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.	tmpzr1t_l9r_go_relaxed.owl	IL-9-mediated signaling pathway|interleukin-9-mediated signalling pathway							bf	2012-03-22T10:20:33Z					biological_process											owl:Class	
GO:0060919	biolink:NamedThing	auxin influx	The process involved in the transport of auxin into the cell.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-09-28T02:49:18Z					biological_process											owl:Class	
GO:0048795	biolink:NamedThing	swim bladder morphogenesis	The process in which the anatomical structure of the swim bladder is generated and organized. The swim bladder is used by some fishes to maintain buoyancy and may function in addition as a sound producing organ, a sound receptor, and a respiratory organ.	tmpzr1t_l9r_go_relaxed.owl	gas bladder morphogenesis													biological_process											owl:Class	
GO:0034798	biolink:NamedThing	fosfomycin 2-L-cysteine ligase activity	Catalysis of the reaction: hydrogen (2R,3S)-3-methyloxiran-2-ylphosphonic acid + L-cysteine = hydrogen (1R,2R)-1-L-cysteine-2-hydroxypropylphosphonic acid.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r1074									molecular_function											owl:Class	
GO:0033964	biolink:NamedThing	glycosphingolipid deacylase activity	Catalysis of the hydrolysis of gangliosides and neutral glycosphingolipids, releasing fatty acids to form the lyso-derivatives.	tmpzr1t_l9r_go_relaxed.owl	glycosphingolipid amidohydrolase activity|glycosphingolipid ceramide deacylase activity				MetaCyc:3.5.1.69-RXN|EC:3.5.1.69									molecular_function											owl:Class	
GO:0050361	biolink:NamedThing	tryptophan 2-monooxygenase activity	Catalysis of the reaction: L-tryptophan + O(2) = CO(2) + H(2)O + indole-3-acetamide.	tmpzr1t_l9r_go_relaxed.owl	L-tryptophan:oxygen 2-oxidoreductase (decarboxylating)				RHEA:16165|MetaCyc:TRYPTOPHAN-2-MONOOXYGENASE-RXN|KEGG_REACTION:R00679|EC:1.13.12.3									molecular_function											owl:Class	
GO:0102261	biolink:NamedThing	8-hydroxy-5-deazaflavin:NADPH oxidoreductase activity	Catalysis of the reaction: NADP + a reduced coenzyme F420 <=> NADPH + H+ + an oxidized coenzyme F420.	tmpzr1t_l9r_go_relaxed.owl					EC:1.5.1.40|RHEA:31363|MetaCyc:RXN-12450									molecular_function											owl:Class	
GO:1905307	biolink:NamedThing	response to miconazole	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a miconazole stimulus.	tmpzr1t_l9r_go_relaxed.owl								al	2016-07-06T11:55:22Z					biological_process											owl:Class	
GO:0070764	biolink:NamedThing	gamma-secretase-Delta1 complex	A protein complex that is formed by the association of the Notch ligand Delta1 with the gamma-secretase complex.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-06-29T01:11:51Z					cellular_component											owl:Class	
GO:1900237	biolink:NamedThing	positive regulation of induction of conjugation with cellular fusion	Any process that activates or increases the frequency, rate or extent of induction of conjugation with cellular fusion.	tmpzr1t_l9r_go_relaxed.owl	up regulation of induction of conjugation with cellular fusion|up-regulation of induction of conjugation with cellular fusion|upregulation of induction of conjugation with cellular fusion							al	2012-03-26T10:14:16Z					biological_process											owl:Class	
GO:0043136	biolink:NamedThing	glycerol-3-phosphatase activity	Catalysis of the reaction: glycerol 3-phosphate + H2O = glycerol + phosphate.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-8955794|MetaCyc:GLYCEROL-1-PHOSPHATASE-RXN									molecular_function											owl:Class	
GO:0097751	biolink:NamedThing	spore-bearing structure formation	The process of generating a spore-bearing structure. A spore-bearing structure is an anatomical structure that produces new spores.	tmpzr1t_l9r_go_relaxed.owl	sporangium formation|sporophore formation							pr	2017-01-11T13:55:24Z					biological_process											owl:Class	
GO:0043208	biolink:NamedThing	glycosphingolipid binding	Binding to glycosphingolipid, a compound with residues of sphingoid and at least one monosaccharide.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1901604	biolink:NamedThing	dethiobiotin transmembrane transporter activity	Enables the transfer of dethiobiotin from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl								al	2012-11-08T14:42:53Z					molecular_function											owl:Class	
GO:0003693	biolink:NamedThing	P-element binding	Binding to a P-element, a class of Drosophila transposon responsible for hybrid dysgenesis.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0047671	biolink:NamedThing	anthranilate adenylyltransferase activity	Catalysis of the reaction: anthranilate + ATP = N-adenylylanthranilate + diphosphate + H(+).	tmpzr1t_l9r_go_relaxed.owl	anthranilic acid adenylyltransferase activity|ATP:anthranilate adenylyltransferase activity|ATP:anthranilate N-adenylyltransferase activity				EC:6.3.2.40|RHEA:35091|MetaCyc:ANTHRANILATE-ADENYLYLTRANSFERASE-RXN|KEGG_REACTION:R00979									molecular_function											owl:Class	
GO:0032540	biolink:NamedThing	positive regulation of host-seeking behavior	Any process that activates or increases the frequency, rate or extent of any behavior associated with finding a host organism.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of host-seeking behavior|activation of host-seeking behavior|up regulation of host-seeking behavior|positive regulation of host-seeking behaviour|stimulation of host-seeking behavior|upregulation of host-seeking behavior													biological_process											owl:Class	
GO:2000123	biolink:NamedThing	positive regulation of stomatal complex development	Any process that activates or increases the frequency, rate or extent of stomatal complex development.	tmpzr1t_l9r_go_relaxed.owl								dhl	2010-09-27T08:28:28Z					biological_process											owl:Class	
GO:0018363	biolink:NamedThing	peroxidase-heme linkage via dihydroxyheme-L-aspartyl ester-L-glutamyl ester-L-methionine sulfonium	The covalent linkage of heme to peroxidase via dihydroxyheme-L-aspartyl ester-L-glutamyl ester-L-methionine sulfonium.	tmpzr1t_l9r_go_relaxed.owl	peroxidase-heme linkage via dihydroxyheme-L-aspartyl ester-L-glutamyl ester-L-methionine sulphonium|peroxidase-haem linkage via dihydroxyhaem-L-aspartyl ester-L-glutamyl ester-L-methionine sulfonium				RESID:AA0280							GO:0019925		biological_process											owl:Class	
GO:0047147	biolink:NamedThing	trimethylsulfonium-tetrahydrofolate N-methyltransferase activity	Catalysis of the reaction: (6S)-5,6,7,8-tetrahydrofolate + trimethylsulfonium = (6S)-5-methyl-5,6,7,8-tetrahydrofolate + dimethyl sulfide + H(+).	tmpzr1t_l9r_go_relaxed.owl	trimethylsulphonium-tetrahydrofolate N-methyltransferase activity|trimethylsulfonium-tetrahydrofolate methyltransferase activity|trimethylsulfonium:tetrahydrofolate N-methyltransferase activity				MetaCyc:2.1.1.19-RXN|EC:2.1.1.19|RHEA:13693|KEGG_REACTION:R02573									molecular_function											owl:Class	
GO:0008263	biolink:NamedThing	pyrimidine-specific mismatch base pair DNA N-glycosylase activity	Catalysis of the removal of mismatched pyrimidine bases in DNA. Enzymes with this activity recognize and remove pyrimidines present in mismatches by cleaving the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar. The reaction releases a free base and leaves an apyrimidinic (AP) site.	tmpzr1t_l9r_go_relaxed.owl	G/T-mismatch-specific thymine-DNA glycosylase activity													molecular_function											owl:Class	
GO:1903588	biolink:NamedThing	negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis	Any process that stops, prevents or reduces the frequency, rate or extent of blood vessel endothelial cell proliferation involved in sprouting angiogenesis.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of blood vessel endothelial cell proliferation during sprouting angiogenesis|downregulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis|negative regulation of blood vessel endothelial cell proliferation during sprouting angiogenesis|downregulation of blood vessel endothelial cell proliferation during sprouting angiogenesis|down-regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis|inhibition of blood vessel endothelial cell proliferation during sprouting angiogenesis|down regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis|down regulation of blood vessel endothelial cell proliferation during sprouting angiogenesis|inhibition of blood vessel endothelial cell proliferation involved in sprouting angiogenesis							pga	2014-11-04T11:39:39Z					biological_process											owl:Class	
GO:0097677	biolink:NamedThing	STAT family protein binding	Binding to a member of the signal transducers and activators of transcription (STAT) protein family. STATs are, as the name indicates, both signal transducers and transcription factors. STATs are activated by cytokines and some growth factors and thus control important biological processes including cell growth, cell differentiation, apoptosis and immune responses.	tmpzr1t_l9r_go_relaxed.owl	signal transducers and activators of transcription family protein binding							pr	2014-11-04T11:31:03Z					molecular_function											owl:Class	
GO:0060851	biolink:NamedThing	vascular endothelial growth factor receptor signaling pathway involved in lymphatic endothelial cell fate commitment	The series of molecular signals generated as a consequence of vascular endothelial growth factor receptor binding to one of its physiological ligands that contributes to the commitment of a venous endothelial cell to a lymphatic endothelial cell fate.	tmpzr1t_l9r_go_relaxed.owl	vascular endothelial growth factor receptor signalling pathway involved in lymphatic endothelial cell fate commitment							dph	2009-08-12T11:45:19Z					biological_process											owl:Class	
GO:0008802	biolink:NamedThing	betaine-aldehyde dehydrogenase activity	Catalysis of the reaction: betaine aldehyde + NAD+ + H2O = betaine + NADH + H+.	tmpzr1t_l9r_go_relaxed.owl	betaine aldehyde oxidase activity|BetB|betaine aldehyde dehydrogenase activity|BADH activity|betaine-aldehyde:NAD+ oxidoreductase activity				MetaCyc:BADH-RXN|Reactome:R-HSA-6797955|EC:1.2.1.8|RHEA:15305									molecular_function											owl:Class	
GO:0019554	biolink:NamedThing	glutamate catabolic process to oxaloacetate	The chemical reactions and pathways resulting in the breakdown of glutamate into other compounds, including oxaloacetate.	tmpzr1t_l9r_go_relaxed.owl	glutamate degradation to oxaloacetate|glutamate breakdown to oxaloacetate													biological_process											owl:Class	
GO:0060905	biolink:NamedThing	regulation of induction of conjugation upon nitrogen starvation	Any process that modulates the frequency of induction of conjugation upon nitrogen starvation, the process in which a cell initiates conjugation with cellular fusion upon nitrogen starvation.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-08-14T01:17:50Z					biological_process											owl:Class	
GO:0043688	biolink:NamedThing	conversion of aspartyl-tRNA to asparaginyl-tRNA	The modification process that results in the conversion of aspartate charged on a tRNA(Asn) to asparaginyl-tRNA.	tmpzr1t_l9r_go_relaxed.owl						Note that this process has been observed in some archaeal and bacterial species.								biological_process											owl:Class	
GO:0046371	biolink:NamedThing	dTDP-mannose metabolic process	The chemical reactions and pathways involving dTDP-mannose, a substance composed of mannose in glycosidic linkage with deoxyribosylthymine diphosphate.	tmpzr1t_l9r_go_relaxed.owl	dTDP-mannose metabolism													biological_process											owl:Class	
GO:0042619	biolink:NamedThing	poly-hydroxybutyrate biosynthetic process	The chemical reactions and pathways resulting in the formation of poly-hydroxybutyrate (PHB), a polymer of beta-hydroxybutyrate and a common storage material of prokaryotic cells.	tmpzr1t_l9r_go_relaxed.owl	poly-hydroxybutyrate anabolism|poly-hydroxybutyrate biosynthesis|PHB biosynthesis|poly-hydroxybutyrate formation|PHB biosynthetic process|poly-hydroxybutyrate synthesis													biological_process											owl:Class	
GO:0099192	biolink:NamedThing	cerebellar Golgi cell to granule cell synapse	A synapse formed by a cerebellar Golgi cell synapsing on to a cerebellar granule cell.	tmpzr1t_l9r_go_relaxed.owl								dos	2017-12-20T16:12:25Z					cellular_component											owl:Class	
GO:0097318	biolink:NamedThing	invasive growth in response to abiotic stimulus	The growth of colonies in filamentous chains of cells as a result of a abiotic stimulus. An example of this process is found in Candida albicans.	tmpzr1t_l9r_go_relaxed.owl								pr	2012-05-31T10:39:31Z					biological_process											owl:Class	
GO:0106301	biolink:NamedThing	arachidonic acid 5,6-epoxygenase activity	Catalysis of an NADPH- and oxygen-dependent reaction that converts arachidonic acid to cis-5,6-epoxyeicosatrienoic acid.	tmpzr1t_l9r_go_relaxed.owl					RHEA:49936			hjd	2020-08-28T19:08:45Z					molecular_function											owl:Class	
GO:0034568	biolink:NamedThing	isoproturon dimethylaminedehydrogenase activity	Catalysis of the reaction: isoproturon + H2O = formaldehyde + monodemethylisoproturon + 2 H+ + 2 e-.	tmpzr1t_l9r_go_relaxed.owl					EC:1.5.99.-|UM-BBD_reactionID:r0892									molecular_function											owl:Class	
GO:0047800	biolink:NamedThing	cysteamine dioxygenase activity	Catalysis of the reaction: cysteamine + O(2) = H(+) + hypotaurine.	tmpzr1t_l9r_go_relaxed.owl	cysteamine:oxygen oxidoreductase activity|cysteamine oxygenase activity|2-aminoethanethiol:oxygen oxidoreductase activity|persulfurase activity				KEGG_REACTION:R02467|MetaCyc:CYSTEAMINE-DIOXYGENASE-RXN|EC:1.13.11.19|Reactome:R-HSA-6814153|RHEA:14409									molecular_function											owl:Class	
GO:0042628	biolink:NamedThing	mating plug formation	The deposition of a plug of sperm or other gelatinous material into the opening of the vulva by a male at the termination of copulation. Probably acts to prevent subsequent matings by other males.	tmpzr1t_l9r_go_relaxed.owl	copulatory plug biosynthesis|copulatory plug deposition|mating plug deposition|copulatory plug formation													biological_process											owl:Class	
GO:0004052	biolink:NamedThing	arachidonate 12(S)-lipoxygenase activity	Catalysis of the reaction: arachidonate + O(2) = (5Z,8Z,10E,12S,14Z)-12-hydroperoxyicosa-5,8,10,14-tetraenoate.	tmpzr1t_l9r_go_relaxed.owl	LTA4 synthase activity|delta12-lipoxygenase activity|12Delta-lipoxygenase activity|leukotriene A4 synthase|C-12 lipoxygenase activity|12-lipoxygenase activity|arachidonate:oxygen 12-oxidoreductase activity|12S-lipoxygenase activity				Reactome:R-HSA-9026007|Reactome:R-HSA-9026006|Reactome:R-HSA-2161948|Reactome:R-HSA-2161964|RHEA:10428|Reactome:R-HSA-9025957|Reactome:R-HSA-9024983|EC:1.13.11.31|MetaCyc:ARACHIDONATE-12-LIPOXYGENASE-RXN|KEGG_REACTION:R01596|Reactome:R-HSA-2161950									molecular_function											owl:Class	
GO:0051061	biolink:NamedThing	ADP reductase activity	Catalysis of the reaction: dADP + thioredoxin disulfide + H2O = ADP + thioredoxin.	tmpzr1t_l9r_go_relaxed.owl	ADP reduction				MetaCyc:ADPREDUCT-RXN|RHEA:28034									molecular_function											owl:Class	
GO:0062161	biolink:NamedThing	regulation of pyocyanine biosynthetic process	Any process that modulates the frequency, rate or extent of a pyocyanine biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of pyocyanin biosynthetic process							dph	2019-11-06T14:36:27Z					biological_process											owl:Class	
GO:0039666	biolink:NamedThing	virion attachment to host cell pilus	The process by which a virion attaches to a host cell by binding to a pilus on the host cell surface. Pili are retractile filaments that protrude from gram-negative bacteria. Filamentous viruses can attach to the pilus tip, whereas icosahedral viruses can attach to the pilus side.	tmpzr1t_l9r_go_relaxed.owl	pilus-mediated viral adsorption onto host cell|pilus-adsorption protein|viral attachment to host cell pilus|pilus-mediated viral attachment to host cell				VZ:981			bf	2013-08-29T13:31:10Z					biological_process											owl:Class	
GO:0048212	biolink:NamedThing	Golgi vesicle uncoating	The process in which Golgi vesicle coat proteins are depolymerized, and released for reuse.	tmpzr1t_l9r_go_relaxed.owl	Golgi vesicle coat protein depolymerization|Golgi vesicle coat depolymerization|Golgi-derived vesicle uncoating|dictyosome vesicle coat depolymerization													biological_process											owl:Class	
GO:0072319	biolink:NamedThing	vesicle uncoating	A protein depolymerization process that results in the disassembly of vesicle coat proteins.	tmpzr1t_l9r_go_relaxed.owl	vesicle coat disassembly							mah	2010-10-26T12:09:21Z					biological_process											owl:Class	
GO:0060440	biolink:NamedThing	trachea formation	The process pertaining to the initial formation of a trachea from unspecified parts. The process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the trachea is recognizable. The trachea is the portion of the airway that attaches to the bronchi as it branches.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0060233	biolink:NamedThing	oenocyte delamination	The negative regulation of cell adhesion process in which an oenocyte splits off of an existing epithelial sheet.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0140661	biolink:NamedThing	cytoskeletal motor inhibitor activity	Binds to and stops, prevents, or reduces the activity of a motor protein.	tmpzr1t_l9r_go_relaxed.owl	motor activity inhibitor activity	https://github.com/geneontology/go-ontology/issues/21627|https://github.com/geneontology/go-ontology/issues/21756						pg	2021-06-16T11:22:54Z					molecular_function											owl:Class	
GO:1990630	biolink:NamedThing	IRE1-RACK1-PP2A complex	A protein complex consisting of IRE1 (Inositol-requiring enzyme-1), RACK1 (Receptor of activated protein kinase C 1, GNB2L1) and PP2A (protein phosphatase 2A). RACK1 acts as an adaptor to bridge an interaction between IRE1 and PP2A.	tmpzr1t_l9r_go_relaxed.owl	IRE1alpha-RACK1-PP2A complex|ERN1-RACK1-PP2A complex							bf	2015-02-05T15:37:58Z					cellular_component											owl:Class	
GO:1901030	biolink:NamedThing	positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway	Any process that activates or increases the frequency, rate or extent of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of MOMP|positive regulation of mitochondrial outer membrane permeabilization|up regulation of MOMP|upregulation of mitochondrial outer membrane permeabilization|up-regulation of MOMP|up-regulation of mitochondrial outer membrane permeabilization|activation of MOMP|upregulation of MOMP|activation of mitochondrial outer membrane permeabilization|up regulation of mitochondrial outer membrane permeabilization					Caspase 8 may be annotated to this term when it is shown to stimulate MOMP by cleaving the BH3-only protein BID.		pr	2012-06-20T09:19:46Z					biological_process											owl:Class	
GO:0033894	biolink:NamedThing	ribonuclease P4 activity	Catalysis of the endonucleolytic cleavage of RNA, removing 3'-extranucleotides from tRNA precursor.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:3.1.26.7-RXN|EC:3.1.26.7									molecular_function											owl:Class	
GO:0052654	biolink:NamedThing	L-leucine transaminase activity	Catalysis of the reaction: 2-oxoglutarate + L-leucine = 4-methyl-2-oxopentanoate + L-glutamatic acid.	tmpzr1t_l9r_go_relaxed.owl	L-leucine aminotransferase activity				EC:2.6.1.42|MetaCyc:BRANCHED-CHAINAMINOTRANSFERLEU-RXN|KEGG_REACTION:R01090									molecular_function											owl:Class	
GO:0021844	biolink:NamedThing	interneuron sorting involved in substrate-independent cerebral cortex tangential migration	The establishment and response to guidance cues that distribute interneurons to different cerebral cortex structures.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1990503	biolink:NamedThing	dendritic lamellar body	A specialized secretory organelle found in neurons and associated with the formation of dendrodendritic gap junctions.	tmpzr1t_l9r_go_relaxed.owl	DLB							sl	2014-09-30T20:47:28Z					cellular_component											owl:Class	
GO:2000522	biolink:NamedThing	positive regulation of immunological synapse formation	Any process that activates or increases the frequency, rate or extent of immunological synapse formation.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of formation of immunological synapse							ebc	2011-03-23T10:18:23Z					biological_process											owl:Class	
GO:0150087	biolink:NamedThing	multiple synapse bouton, contacting single dendrite	A single axon terminal bouton making contact onto two or more dendritic spines protruding from the same dendrite.	tmpzr1t_l9r_go_relaxed.owl	type 1 multisynapse bouton|MSB1|type 1 multi-synaptic bouton|type 1 multisynaptic bouton|type 1 multi-synapse bouton|type 1 multiple spine synapse bouton|type 1 multiple-synapse bouton							bc	2018-08-08T13:26:34Z					cellular_component											owl:Class	
GO:0150086	biolink:NamedThing	multiple synapse bouton	A single axon terminal bouton making contact onto two or more dendritic spines protruding either from a single dendrite or from multiple dendrites.	tmpzr1t_l9r_go_relaxed.owl	multisynaptic bouton|multiple-synapse bouton|multi-synaptic bouton|MSB|multisynapse bouton|multi-synapse|multisynapse|multiple synapse|multi-synapse bouton|multiple spine synapse bouton							bc	2018-08-08T13:21:17Z					cellular_component											owl:Class	
GO:0097118	biolink:NamedThing	neuroligin clustering involved in postsynaptic membrane assembly	The receptor clustering process involved in assembly of the postsynaptic membrane in which neuroligins are localized to distinct domains in the cell membrane. Neuroligins are neuronal cell surface proteins on the postsynaptic membrane that mediate synapse formation between neurons.	tmpzr1t_l9r_go_relaxed.owl	neuroligin clustering|postsynaptic neuroligin clustering|Nlgn clustering							pr	2011-07-31T05:47:25Z					biological_process											owl:Class	
GO:0034062	biolink:NamedThing	5'-3' RNA polymerase activity	Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1); the synthesis of RNA from ribonucleotide triphosphates in the presence of a nucleic acid template, via extension of the 3'-end.	tmpzr1t_l9r_go_relaxed.owl	RNA nucleotidyltransferase activity|ribonucleic acid transcriptase activity|ribonucleate nucleotidyltransferase activity|transcriptase|ribonucleic transcriptase activity|RNA transcriptase activity|ribonucleate polymerase activity|RNA polymerase activity|ribonucleic acid nucleotidyltransferase|C RNA formation factors|C ribonucleic acid formation factors|ribonucleic polymerase activity|ribonucleic acid polymerase activity				Reactome:R-HSA-6786881|Reactome:R-HSA-5696807									molecular_function											owl:Class	
GO:0050461	biolink:NamedThing	L-mimosine synthase activity	Catalysis of the reaction: 3,4-dihydroxypyridine + O-acetyl-L-serine = 3-(3,4-dihydroxypyridinium-1-yl)-L-alanine + acetate.	tmpzr1t_l9r_go_relaxed.owl	O(3)-acetyl-L-serine acetate-lyase (adding 3,4-dihydroxypyridin-1-yl) activity|3-O-acetyl-L-serine:3,4-dihydroxypyridine 1-(2-amino-2-carboxyethyl)transferase activity|O3-acetyl-L-serine acetate-lyase (adding 3,4-dihydroxypyridin-1-yl)|O3-acetyl-L-serine:3,4-dihydroxypyridine 1-(2-amino-2-carboxyethyl)transferase activity				RHEA:12693|MetaCyc:RXN-7461|KEGG_REACTION:R04091|EC:2.5.1.52									molecular_function											owl:Class	
GO:0036520	biolink:NamedThing	astrocyte-dopaminergic neuron signaling	Cell-cell signaling that mediates the transfer of information from an astrocyte to a dopaminergic neuron.	tmpzr1t_l9r_go_relaxed.owl	astrocyte-dopaminergic neuron cell signaling|mesencephalic dopaminergic neuron-astrocyte crosstalk|midbrain dopaminergic neuron-astrocyte crosstalk|dopaminergic neuron-astrocyte crosstalk							bf	2016-02-29T14:05:47Z					biological_process											owl:Class	
GO:0150098	biolink:NamedThing	glial cell-neuron signaling	Cell-cell signaling that mediates the transfer of information from a glial cell to a neuron. This signaling has been shown to be mediated by various molecules, depending on which glial cells release them, and in which tissues the signalling occurs, e.g. microglial cell-derived nerve growth factor (NGF) in the retina, or microglial cell-derived superoxide ions in the cerebellum.	tmpzr1t_l9r_go_relaxed.owl	glial cell-neurone signalling|glia-neuron signalling|glia-neuron signaling|glia-neurone signalling|glial cell-neurone singaling|glial cell- neuron signalling|glia-neurone signaling							bc	2018-12-17T12:28:09Z					biological_process											owl:Class	
GO:0062082	biolink:NamedThing	HLA-E specific inhibitory MHC class Ib receptor activity	Combining with a MHC class Ib molecule of the HLA-A subclass to mediate signaling that inhibits activation of a lymphocyte.	tmpzr1t_l9r_go_relaxed.owl								dph	2018-10-15T15:06:22Z					molecular_function											owl:Class	
GO:0046826	biolink:NamedThing	negative regulation of protein export from nucleus	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of proteins from the nucleus into the cytoplasm.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of protein-nucleus export|down regulation of protein export from nucleus|downregulation of protein export from nucleus|inhibition of protein export from nucleus|negative regulation of protein export out of nucleus|negative regulation of protein transport from nucleus to cytoplasm|down-regulation of protein export from nucleus|negative regulation of protein export from cell nucleus													biological_process											owl:Class	
GO:0006430	biolink:NamedThing	lysyl-tRNA aminoacylation	The process of coupling lysine to lysyl-tRNA, catalyzed by lysyl-tRNA synthetase. The lysyl-tRNA synthetase is a  class-II synthetase. The activated amino acid is transferred to the 3'-OH group of a lysine-accetping tRNA.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0045317	biolink:NamedThing	equator specification	The formation and development of the equator that forms the boundary between the photoreceptors in the dorsal sector of the eye and those in the ventral sector, dividing the eye into dorsal and ventral halves.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1902185	biolink:NamedThing	positive regulation of shoot apical meristem development	Any process that activates or increases the frequency, rate or extent of shoot apical meristem development.	tmpzr1t_l9r_go_relaxed.owl	activation of promeristem development|upregulation of SAM development|up regulation of shoot apical meristem development|positive regulation of SAM development|upregulation of promeristem development|up regulation of primary shoot meristem development|upregulation of shoot apical meristem development|positive regulation of promeristem development|activation of primary shoot meristem development|up-regulation of shoot apical meristem development|activation of shoot apical meristem development|activation of SAM development|up regulation of SAM development|up-regulation of SAM development|up-regulation of primary shoot meristem development|up-regulation of promeristem development|positive regulation of primary shoot meristem development|upregulation of primary shoot meristem development|up regulation of promeristem development							tb	2013-05-31T16:34:05Z					biological_process											owl:Class	
GO:0090554	biolink:NamedThing	phosphatidylcholine floppase activity	Catalysis of the movement of phosphatidylcholine from the cytosolic to the exoplasmic leaftlet of a membrane, using energy from the hydrolysis of ATP.	tmpzr1t_l9r_go_relaxed.owl	ATP-dependent phosphatidylcholine transporter activity|phosphatidylcholine-translocating ATPase activity|phosphatidylcholine floppase activity (cytosolic to exoplasmic leaftlet)|ATPase-coupled phosphatidylcholine transporter activity				RHEA:38583			tb	2013-10-24T16:07:20Z					molecular_function											owl:Class	
GO:1901346	biolink:NamedThing	negative regulation of vasculature development involved in avascular cornea development in camera-type eye	Any negative regulation of vasculature development that is involved in developing an avascular cornea of a camera-type eye.	tmpzr1t_l9r_go_relaxed.owl	downregulation of vascular system development involved in avascular cornea development|down-regulation of vasculature development involved in avascular cornea development in camera-type eye|inhibition of vascular system development involved in avascular cornea development in camera-type eye|inhibition of vascular system development involved in avascular cornea development|downregulation of vascular system development involved in avascular cornea development in camera-type eye|downregulation of vasculature development involved in avascular cornea development in camera-type eye|negative regulation of vascular system development involved in avascular cornea development|inhibition of vasculature development involved in avascular cornea development in camera-type eye|down-regulation of vascular system development involved in avascular cornea development in camera-type eye|negative regulation of vasculature development involved in avascular cornea development|down regulation of vasculature development involved in avascular cornea development|downregulation of vasculature development involved in avascular cornea development|down regulation of vascular system development involved in avascular cornea development|down regulation of vasculature development involved in avascular cornea development in camera-type eye|down-regulation of vascular system development involved in avascular cornea development|down regulation of vascular system development involved in avascular cornea development in camera-type eye|negative regulation of vascular system development involved in avascular cornea development in camera-type eye|down-regulation of vasculature development involved in avascular cornea development|inhibition of vasculature development involved in avascular cornea development							bf	2012-09-07T15:53:40Z					biological_process											owl:Class	
GO:0050988	biolink:NamedThing	N-terminal peptidyl-methionine carboxylation	The carboxylation of the N-terminal methionine of proteins to form the derivative N-carboxy-L-methionine.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0363									biological_process											owl:Class	
GO:0006975	biolink:NamedThing	DNA damage induced protein phosphorylation	The widespread phosphorylation of various molecules, triggering many downstream processes, that occurs in response to the detection of DNA damage.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0002202	biolink:NamedThing	somatic diversification of variable lymphocyte receptors of jawless fish	The somatic process that results in the generation of sequence diversity of the variable lymphocyte receptors (VLR) of jawless fish.	tmpzr1t_l9r_go_relaxed.owl						Note that jawless fish refers to both lampreys (Petremyzontidae, ncbi_taxonomy_id:7746) and hagfish (Myxinidae, ncbi_taxonomy_id:7762).								biological_process											owl:Class	
GO:0033402	biolink:NamedThing	UUC codon-amino acid adaptor activity	A triplet codon-amino acid adaptor activity that recognizes a UUC codon.	tmpzr1t_l9r_go_relaxed.owl	TTC codon-amino acid adaptor activity|phenylalanine tRNA					Note that in the standard genetic code, TTC codes for phenylalanine.								molecular_function											owl:Class	
GO:0036159	biolink:NamedThing	inner dynein arm assembly	The aggregation, arrangement and bonding together of a set of components to form an axonemal dynein inner arm, an inner arm structure present on the outer doublet microtubules of ciliary and flagellar axonemes.	tmpzr1t_l9r_go_relaxed.owl	IDA assembly							bf	2012-03-21T02:25:01Z					biological_process											owl:Class	
GO:0018860	biolink:NamedThing	anthranilate-CoA ligase activity	Catalysis of the reaction: ATP + anthranilate + CoA = AMP + diphosphate + anthranilyl-CoA.	tmpzr1t_l9r_go_relaxed.owl	anthranilate--CoA ligase activity|anthraniloyl coenzyme A synthetase activity|2-aminobenzoate-CoA ligase activity|2-aminobenzoate coenzyme A ligase activity|anthranilate:CoA ligase (AMP-forming)|2-aminobenzoate-coenzyme A ligase activity				MetaCyc:AMINOBENZCOALIG-RXN|UM-BBD_reactionID:r0341|EC:6.2.1.32|KEGG_REACTION:R00982|RHEA:10828									molecular_function											owl:Class	
GO:0098676	biolink:NamedThing	modulation of host virulence by virus	Any process by which a virus modulates the ability of its host to infect and/or damage an organism for which it is a host.  Typically this involves a phage modulating the virulence of a bacterium.  Mechanisms include the expression of factors that modulate a bacterial adhesion to a host cell, spread through host tissues, production exotoxins or provide protection against host immune defenses.	tmpzr1t_l9r_go_relaxed.owl					VZ:3965			dos	2017-01-19T11:59:46Z					biological_process											owl:Class	
GO:0004528	biolink:NamedThing	phosphodiesterase I activity	Catalysis of the sequential hydrolytic removal of 5'-nucleotides from the 3'-hydroxy termini of 3'-hydroxy-terminated oligonucleotides.	tmpzr1t_l9r_go_relaxed.owl	5'NPDE activity|exonuclease I activity|5'-NPDase activity|orthophosphoric diester phosphohydrolase activity|5'-phosphodiesterase activity|phosphodiesterase activity|nucleotide pyrophosphatase/phosphodiesterase I activity|5'-exonuclease activity|PDE I activity|oligonucleate 5'-nucleotidohydrolase activity|5'-PDE activity|5' nucleotide phosphodiesterase/alkaline phosphodiesterase I activity|5'-nucleotide phosphodiesterase activity|alkaline phosphodiesterase activity|5'-PDase activity				EC:3.1.4.1|MetaCyc:3.1.4.1-RXN									molecular_function											owl:Class	
GO:0018140	biolink:NamedThing	peptide cross-linking via L-cysteine thiazolecarboxylic acid	The chemical reactions and pathways resulting in the formation of a peptidyl cysteine-peptidyl cysteine cross-link by the condensation of a cysteine thiol with the carbonyl of the preceding residue and alpha-beta dehydrogenation.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0244									biological_process											owl:Class	
GO:0002314	biolink:NamedThing	germinal center B cell differentiation	The process in which a B cell in the spleen acquires the specialized features of a germinal center B cell. Germinal center B cells are rapidly cycling B cells which have downregulated IgD expression and exhibit high levels of binding by peanut agglutinin (PNA).	tmpzr1t_l9r_go_relaxed.owl	germinal center B cell development|germinal center B-cell differentiation|germinal center B lymphocyte differentiation|germinal center B-lymphocyte differentiation					Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.								biological_process											owl:Class	
GO:0060152	biolink:NamedThing	microtubule-based peroxisome localization	The microtubule-based process in which a peroxisome is transported to, and/or maintained in, a specific location. A peroxisome is a small membrane-bounded organelle that uses dioxygen (O2) to oxidize organic molecules.	tmpzr1t_l9r_go_relaxed.owl	microtubule-based peroxisome localisation													biological_process											owl:Class	
GO:0102280	biolink:NamedThing	choline monooxygenase activity (NADP-dependent)	Catalysis of the reaction: choline + NADP = betaine aldehyde + NADPH + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-12582									molecular_function											owl:Class	
GO:0000953	biolink:NamedThing	branched-chain amino acid catabolic process to carboxylic acid via Ehrlich pathway	The chemical reactions and pathways involving the catabolism of amino acids to produce carboxylic acids with one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. When a branched chain family amino acid, leucine, isoleucine, or valine, is used as the substrate, 3-methylbutanoate, 2-methylbutanoate, or 2-methylpropanoate, respectively, is produced. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of carboxylic acids, sometimes collectively referred to as fusel acids. Depending on the redox state of the cells, alcohol derivatives may be produced instead of carboxylic acids.	tmpzr1t_l9r_go_relaxed.owl	branched chain family amino acid catabolic process to carboxylic acid via Ehrlich pathway													biological_process											owl:Class	
GO:1900662	biolink:NamedThing	negative regulation of emericellamide A biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of emericellamide A biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	inhibition of emericellamide A synthesis|negative regulation of emericellamide A biosynthesis|down-regulation of emericellamide A biosynthetic process|downregulation of emericellamide A biosynthesis|downregulation of emericellamide A formation|negative regulation of emericellamide A anabolism|inhibition of emericellamide A anabolism|down regulation of emericellamide A formation|inhibition of emericellamide A biosynthesis|down-regulation of emericellamide A biosynthesis|down regulation of emericellamide A anabolism|down-regulation of emericellamide A synthesis|inhibition of emericellamide A formation|negative regulation of emericellamide A formation|down-regulation of emericellamide A anabolism|inhibition of emericellamide A biosynthetic process|negative regulation of emericellamide A synthesis|downregulation of emericellamide A biosynthetic process|downregulation of emericellamide A anabolism|down regulation of emericellamide A synthesis|down regulation of emericellamide A biosynthesis|down regulation of emericellamide A biosynthetic process|downregulation of emericellamide A synthesis|down-regulation of emericellamide A formation							di	2012-05-22T04:13:28Z					biological_process											owl:Class	
GO:0047455	biolink:NamedThing	16-alpha-hydroxyprogesterone dehydratase activity	Catalysis of the reaction: 16-alpha-hydroxyprogesterone = H2O + 16-dehydroprogesterone.	tmpzr1t_l9r_go_relaxed.owl	16-dehydroprogesterone hydratase activity|16-alpha-hydroxyprogesterone dehydroxylase activity|16alpha-hydroxyprogesterone hydro-lyase (16,17-didehydroprogesterone-forming)|16alpha-hydroxyprogesterone hydro-lyase activity|16alpha-hydroxyprogesterone dehydratase activity|16alpha-hydroxyprogesterone dehydroxylase activity|16-alpha-dehydroxylase activity|hydroxyprogesterone dehydroxylase activity|16alpha-dehydroxylase activity				RHEA:12584|MetaCyc:4.2.1.98-RXN|EC:4.2.1.98							GO:0047523		molecular_function											owl:Class	
GO:0106343	biolink:NamedThing	glutarate dioxygenase activity	Catalysis of the reaction glutarate + 2-oxoglutarate + O2 = (S)-2-hydroxyglutarate + succinate + CO2.	tmpzr1t_l9r_go_relaxed.owl					RHEA:13821|EC:1.14.11.64			hjd	2020-11-17T18:04:10Z					molecular_function											owl:Class	
GO:0047289	biolink:NamedThing	galactosyldiacylglycerol alpha-2,3-sialyltransferase activity	Catalysis of the reaction: 1,2-diacyl-3-beta-D-galactosyl-sn-glycerol + CMP-N-acetyl-beta-neuraminate = 1,2-diacyl-3-[3-(alpha-D-N-acetylneuraminyl)-beta-D-galactosyl]-sn-glycerol + CMP + H(+).	tmpzr1t_l9r_go_relaxed.owl	CMP-N-acetylneuraminate:1,2-diacyl-3-beta-D-galactosyl-sn-glycerol N-acetylneuraminyltransferase activity				EC:2.4.99.5|MetaCyc:2.4.99.5-RXN|KEGG_REACTION:R03468|RHEA:11664									molecular_function											owl:Class	
GO:0097268	biolink:NamedThing	cytoophidium	A subcellular filamentary structure where CTP synthase is compartmentalized in a range of organisms including bacteria, yeast, fruit fly, rat and human.	tmpzr1t_l9r_go_relaxed.owl								pr	2012-03-15T01:00:20Z					cellular_component											owl:Class	
GO:2000504	biolink:NamedThing	positive regulation of blood vessel remodeling	Any process that activates or increases the frequency, rate or extent of blood vessel remodeling.	tmpzr1t_l9r_go_relaxed.owl								pr	2011-03-21T10:33:20Z					biological_process											owl:Class	
GO:0006850	biolink:NamedThing	mitochondrial pyruvate transmembrane transport	The process in which pyruvate is transported across a mitochondrial membrane, into or out of the mitochondrion.	tmpzr1t_l9r_go_relaxed.owl	pyruvate transmembrane transport in mitochondria|pyruvate membrane transport in mitochondrion|pyruvate membrane transport in mitochondria|mitochondrial pyruvate transport|pyruvate transmembrane transport in mitochondrion							dph	2013-08-15T11:19:35Z			GO:1902361		biological_process											owl:Class	
GO:0098697	biolink:NamedThing	ryanodine-sensitive calcium-release channel activity involved in regulation of postsynaptic cytosolic calcium levels	Any ryanodine-sensitive calcium-release channel activity that is involved in regulation of postsynaptic cytosolic calcium ion concentration.	tmpzr1t_l9r_go_relaxed.owl								dos	2017-04-04T17:11:38Z					molecular_function											owl:Class	
GO:0005020	biolink:NamedThing	stem cell factor receptor activity	Combining with stem cell factor (SCF) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: ATP + a protein-L-tyrosine = ADP + a protein-L-tyrosine phosphate. Stem cell factor is a cytokine that stimulates mast cell growth and differentiation.	tmpzr1t_l9r_go_relaxed.owl	KIT|KIT ligand receptor activity|SCF receptor activity|KL receptor activity													molecular_function											owl:Class	
GO:1901586	biolink:NamedThing	negative regulation of acid-sensing ion channel activity	Any process that stops, prevents or reduces the frequency, rate or extent of acid-sensing ion channel activity.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of acid-sensing ion channel activity|downregulation of acid-sensing ion channel activity|down regulation of ASIC activity|negative regulation of ASIC activity|down-regulation of ASIC activity|down regulation of acid-sensing ion channel activity|inhibition of ASIC activity|inhibition of acid-sensing ion channel activity|downregulation of ASIC activity							jl	2012-11-07T13:37:32Z					biological_process											owl:Class	
GO:0044526	biolink:NamedThing	formation of peptidyl-cystine persulfide by sulphur transfer from free cysteine	The modification of a peptidyl-cystine residue in a protein by the transfer of a sulfur atom from a free cysteine (in the process converting the free cysteine to alanine) to the peptidyl-cysteine to form peptidyl-cysteine persulfide.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-03-15T09:45:19Z					biological_process											owl:Class	
GO:0072689	biolink:NamedThing	MCM complex assembly	The aggregation, arrangement and bonding together of a set of components to form an MCM complex, a hexameric protein complex required for the initiation and regulation of DNA replication.	tmpzr1t_l9r_go_relaxed.owl								mah	2011-08-12T10:57:29Z					biological_process											owl:Class	
GO:0140481	biolink:NamedThing	ABC-type iron-sulfur cluster transporter activity	Catalysis of the reaction: ATP + H2O + iron-sulfur cluster(in) = ADP + phosphate + iron-sulfur cluster(out).	tmpzr1t_l9r_go_relaxed.owl	ATPase-coupled iron-sulfur cluster transmembrane transporter activity|ATPase-coupled Fe-S cluster transmembrane transporter activity	https://github.com/geneontology/go-ontology/issues/19685			TC:3.A.1.210.1			pg	2020-06-25T17:41:01Z					molecular_function											owl:Class	
GO:0004734	biolink:NamedThing	pyrimidodiazepine synthase activity	Catalysis of the reaction: a pyrimidodiazepine + oxidized glutathione = 6-pyruvoyltetrahydropterin + 2 glutathione.	tmpzr1t_l9r_go_relaxed.owl	pyrimidodiazepine:glutathione-disulfide oxidoreductase (ring-opening, cyclizing)|PDA synthase activity				MetaCyc:1.5.4.1-RXN|RHEA:10720|EC:1.5.4.1									molecular_function											owl:Class	
GO:0016648	biolink:NamedThing	oxidoreductase activity, acting on the CH-NH group of donors, disulfide as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH group acts as a hydrogen or electron donor and reduces disulfide.	tmpzr1t_l9r_go_relaxed.owl	oxidoreductase activity, acting on the CH-NH group of donors, disulphide as acceptor				EC:1.5.4.-									molecular_function											owl:Class	
GO:0097001	biolink:NamedThing	ceramide binding	Binding to a ceramide, a class of lipids composed of sphingosine linked to a fatty acid. Ceramides are a major component of cell membranes.	tmpzr1t_l9r_go_relaxed.owl								pr	2011-03-09T11:34:09Z					molecular_function											owl:Class	
GO:0005610	biolink:NamedThing	laminin-5 complex	A laminin complex composed of alpha3, beta3 and gamma2 polypeptide chains.	tmpzr1t_l9r_go_relaxed.owl	laminin-3A32 complex|laminin-332 complex|laminin-5A complex													cellular_component											owl:Class	
GO:0031371	biolink:NamedThing	ubiquitin conjugating enzyme complex	Any complex that possesses ubiquitin conjugating enzyme activity.	tmpzr1t_l9r_go_relaxed.owl	E2 complex													cellular_component											owl:Class	
GO:0070694	biolink:NamedThing	deoxyribonucleoside 5'-monophosphate N-glycosidase activity	Catalysis of the reaction: a deoxyribonucleoside 5'-monophosphate + H2O = deoxyribose 5-monophosphate + a purine or pyrimidine base.	tmpzr1t_l9r_go_relaxed.owl	deoxynucleoside 5'-monophosphate N-glycosidase activity				Reactome:R-HSA-8953339			mah	2009-06-04T03:06:57Z					molecular_function											owl:Class	
GO:1990969	biolink:NamedThing	modulation by host of viral RNA-binding transcription factor activity	A process in which a host organism modulates the frequency, rate or extent of the activity of a viral RNA-binding transcription factor.	tmpzr1t_l9r_go_relaxed.owl	modulation by host of viral Tat activity							bf	2016-06-21T12:12:31Z					biological_process											owl:Class	
GO:1902610	biolink:NamedThing	response to N-phenylthiourea	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a N-phenylthiourea stimulus.	tmpzr1t_l9r_go_relaxed.owl								rjd	2014-01-08T01:57:49Z					biological_process											owl:Class	
GO:0097721	biolink:NamedThing	ciliary vesicle	A Golgi-derived vesicle to which the ciliary basal body docks via its transitional fibers. Its membrane is compositionally distinct from Golgi membranes, and will become the ciliary membrane once the ciliary vesicle is fused to the plasma membrane. The ciliary vesicle is thought to be formed by multiple smaller vesicles that attach to the transitional fibers and then fuse to form a larger vesicle.	tmpzr1t_l9r_go_relaxed.owl	CV|primary ciliary vesicle							pr	2016-08-30T13:54:38Z					cellular_component											owl:Class	
GO:0005289	biolink:NamedThing	high-affinity L-arginine transmembrane transporter activity	Enables the transfer of arginine from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.	tmpzr1t_l9r_go_relaxed.owl	high affinity arginine transmembrane transporter activity|high-affinity arginine transmembrane transporter activity|high-affinity arginine transporter activity													molecular_function											owl:Class	
GO:1904055	biolink:NamedThing	negative regulation of cholangiocyte proliferation	Any process that stops, prevents or reduces the frequency, rate or extent of cholangiocyte proliferation.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of hepatoblast proliferation|inhibition of cholangiocyte proliferation|downregulation of cholangiocyte proliferation|downregulation of hepatoblast proliferation|down regulation of hepatoblast proliferation|down regulation of cholangiocyte proliferation|down-regulation of cholangiocyte proliferation|negative regulation of hepatoblast proliferation|inhibition of hepatoblast proliferation							sl	2015-03-18T17:56:20Z					biological_process											owl:Class	
GO:1905110	biolink:NamedThing	negative regulation of pulmonary blood vessel remodeling	Any process that stops, prevents or reduces the frequency, rate or extent of pulmonary blood vessel remodeling.	tmpzr1t_l9r_go_relaxed.owl	down regulation of pulmonary blood vessel remodeling|downregulation of pulmonary blood vessel remodeling|inhibition of pulmonary blood vessel remodeling|down-regulation of pulmonary blood vessel remodeling							bc	2016-04-06T13:07:33Z					biological_process											owl:Class	
GO:0120189	biolink:NamedThing	positive regulation of bile acid secretion	Any process that activates or increases the frequency, rate or extent of the controlled release of bile acid from a cell or a tissue.	tmpzr1t_l9r_go_relaxed.owl								krc	2018-07-16T22:36:17Z					biological_process											owl:Class	
GO:0061538	biolink:NamedThing	histamine secretion, neurotransmission	The controlled release of histamine by a cell, in which the histamine acts as a neurotransmitter.	tmpzr1t_l9r_go_relaxed.owl								dph	2013-06-21T16:21:21Z					biological_process											owl:Class	
GO:0046931	biolink:NamedThing	pore complex assembly	The aggregation, arrangement and bonding together of a set of components to form a pore complex. A pore complex is a small opening in a membrane that allows the passage of liquids and/or gases.	tmpzr1t_l9r_go_relaxed.owl	pore biosynthesis|pore formation|pore complex biogenesis|pore-forming toxin activity					See also the cellular component term 'pore complex ; GO:0046930'.								biological_process											owl:Class	
GO:0033820	biolink:NamedThing	DNA alpha-glucosyltransferase activity	Catalysis of the transfer of an alpha-D-glucosyl residue from UDP-glucose to a hydroxymethylcytosine residue in DNA.	tmpzr1t_l9r_go_relaxed.owl	T6-HMC-alpha-glucosyl transferase activity|T4-HMC-alpha-glucosyl transferase activity|UDPglucose-DNA alpha-glucosyltransferase activity|uridine diphosphoglucose-deoxyribonucleate alpha-glucosyltransferase activity|UDP-glucose:DNA alpha-D-glucosyltransferase activity|T2-HMC-alpha-glucosyl transferase activity				EC:2.4.1.26|MetaCyc:2.4.1.26-RXN									molecular_function											owl:Class	
GO:0042994	biolink:NamedThing	cytoplasmic sequestering of transcription factor	The selective interaction of a transcription factor with specific molecules in the cytoplasm, thereby inhibiting its translocation into the nucleus.	tmpzr1t_l9r_go_relaxed.owl	cytoplasmic sequestration of transcription factor|sequestration of transcription factor in cytoplasm|sequestering of transcription factor in cytoplasm|cytoplasmic retention of transcription factor|maintenance of transcription factor protein location in cytoplasm|storage of transcription factor in cytoplasm|transcription factor binding, cytoplasmic sequestering|cytoplasmic storage of transcription factor|retention of transcription factor in cytoplasm													biological_process											owl:Class	
GO:0001682	biolink:NamedThing	tRNA 5'-leader removal	Generation of the mature 5'-end of the tRNA, usually via an endonucleolytic cleavage by RNase P.	tmpzr1t_l9r_go_relaxed.owl	tRNA 5' leader removal													biological_process											owl:Class	
GO:0030132	biolink:NamedThing	clathrin coat of coated pit	The coat found on coated pits and the coated vesicles derived from coated pits; comprises clathrin and the AP-2 adaptor complex.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:1905791	biolink:NamedThing	negative regulation of mechanosensory behavior	Any process that stops, prevents or reduces the frequency, rate or extent of mechanosensory behavior.	tmpzr1t_l9r_go_relaxed.owl	downregulation of mechanosensory behaviour|down-regulation of behavioral response to mechanical stimulus|inhibition of mechanosensory behavior|inhibition of behavioural response to mechanical stimulus|down regulation of mechanosensory behavior|inhibition of behavioral response to mechanical stimulus|down regulation of behavioral response to mechanical stimulus|downregulation of behavioural response to mechanical stimulus|downregulation of mechanosensory behavior|down-regulation of behavioural response to mechanical stimulus|inhibition of mechanosensory behaviour|down regulation of mechanosensory behaviour|down-regulation of mechanosensory behavior|down regulation of behavioural response to mechanical stimulus|downregulation of behavioral response to mechanical stimulus|negative regulation of behavioral response to mechanical stimulus|negative regulation of behavioural response to mechanical stimulus|down-regulation of mechanosensory behaviour|negative regulation of mechanosensory behaviour							hbye	2017-01-09T15:17:15Z					biological_process											owl:Class	
GO:0072747	biolink:NamedThing	cellular response to chloramphenicol	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chloramphenicol stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2012-08-31T12:33:30Z					biological_process											owl:Class	
GO:0090578	biolink:NamedThing	RNA polymerase V transcription regulator complex	A transcription factor complex that acts at a regulatory region of a gene transcribed by RNA polymerase V.	tmpzr1t_l9r_go_relaxed.owl	RNA polymerase V transcription factor complex							tb	2014-05-09T14:04:37Z					cellular_component											owl:Class	
GO:1901231	biolink:NamedThing	positive regulation of non-canonical Wnt signaling pathway via JNK cascade	Any process that activates or increases the frequency, rate or extent of non-canonical Wnt signaling pathway via JNK cascade.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of non-canonical Wnt-activated signaling pathway via JNK cascade|up regulation of non-canonical Wnt receptor signaling pathway via JNK cascade|up-regulation of non-canonical Wnt receptor signaling pathway via JNK cascade|up regulation of non-canonical Wnt receptor signalling pathway via JNK cascade|activation of non-canonical Wnt receptor signalling pathway via JNK cascade|positive regulation of non-canonical Wnt receptor signalling pathway via JNK cascade|upregulation of non-canonical Wnt receptor signaling pathway via JNK cascade|up-regulation of non-canonical Wnt receptor signalling pathway via JNK cascade|activation of non-canonical Wnt receptor signaling pathway via JNK cascade|upregulation of non-canonical Wnt receptor signalling pathway via JNK cascade|positive regulation of non-canonical Wnt receptor signaling pathway via JNK cascade							vk	2012-08-07T14:14:48Z					biological_process											owl:Class	
GO:0046442	biolink:NamedThing	aerobactin metabolic process	The chemical reactions and pathways involving aerobactin (C22H36N4O13), a hydroxamate iron transport compound. It is a conjugate of 6-(N-acetyl-N-hydroxylamine)-2-aminohexanoic acid and citric acid.	tmpzr1t_l9r_go_relaxed.owl	aerobactin metabolism													biological_process											owl:Class	
GO:0047274	biolink:NamedThing	galactinol-sucrose galactosyltransferase activity	Catalysis of the reaction: sucrose + 1-alpha-D-galactosyl-myo-inositol = raffinose + myo-inositol.	tmpzr1t_l9r_go_relaxed.owl	raffinose synthase activity|alpha-D-galactosyl-(1->3)-myo-inositol:sucrose 6-alpha-D-galactosyltransferase activity|galactinol:sucrose 6-galactosyl transferase activity|1-alpha-D-galactosyl-myo-inositol:sucrose 6-alpha-D-galactosyltransferase activity|galactosyltransferase, galactinol-sucrose				RHEA:20161|MetaCyc:2.4.1.82-RXN|EC:2.4.1.82									molecular_function											owl:Class	
GO:0047203	biolink:NamedThing	13-hydroxylupinine O-tigloyltransferase activity	Catalysis of the reaction: 13-hydroxylupanine + 2-methylcrotonoyl-CoA = 13-(2-methylcrotonoyloxy)lupanine + CoA.	tmpzr1t_l9r_go_relaxed.owl	(E)-2-methylcrotonoyl-CoA:13-hydroxylupinine O-2-methylcrotonoyltransferase activity|tigloyl-CoA:13-hydroxylupanine O-tigloyltransferase activity|13-hydroxylupanine acyltransferase activity				MetaCyc:2.3.1.93-RXN|KEGG_REACTION:R04205|RHEA:12360|EC:2.3.1.93									molecular_function											owl:Class	
GO:0033970	biolink:NamedThing	N-malonylurea hydrolase activity	Catalysis of the reaction: 3-oxo-3-ureidopropanoate + H(2)O = H(+) + malonate + urea.	tmpzr1t_l9r_go_relaxed.owl	3-oxo-3-ureidopropanoate amidohydrolase (urea- and malonate-forming) activity|ureidomalonase activity				EC:3.5.1.95|KEGG_REACTION:R07629|MetaCyc:3.5.1.95-RXN|RHEA:17361									molecular_function											owl:Class	
GO:0009288	biolink:NamedThing	bacterial-type flagellum	A motor complex composed of an extracellular helical protein filament coupled to a rotary motor embedded in the cell envelope.	tmpzr1t_l9r_go_relaxed.owl	flagellin-based flagellum													cellular_component											owl:Class	
GO:0044344	biolink:NamedThing	cellular response to fibroblast growth factor stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an fibroblast growth factor stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to FGF stimulus							jl	2010-08-25T02:00:51Z					biological_process											owl:Class	
GO:0097686	biolink:NamedThing	dinoflagellate apical horn	A horn-shaped dinoflagellate apex found in thecate species.	tmpzr1t_l9r_go_relaxed.owl								pr	2014-12-18T09:38:15Z					cellular_component											owl:Class	
GO:0036049	biolink:NamedThing	peptidyl-lysine desuccinylation	The removal of a succinyl group (CO-CH2-CH2-CO) from a succinylated lysine residue in a peptide or protein.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-12-12T09:44:54Z					biological_process											owl:Class	
GO:0097569	biolink:NamedThing	lateral shield	Region of the ventral side of the cell body found in Giardia species (trophozoite stage). It is located posterior on either side of the ventral groove; the upper boundary is the ventral disc, and the lower boundary is marked by the posteriolateral flagella.	tmpzr1t_l9r_go_relaxed.owl						Note that we deem cilium and microtubule-based flagellum to be equivalent. Also note that, due to the asymmetric nature of the Giardia trophozoite, this term is defined spatially as the trophozoite is viewed from the dorsal side, with the two nuclei dorsal to the ventral disc, and the ventral disc toward the anterior.		pr	2014-02-11T13:37:10Z					cellular_component											owl:Class	
GO:0070348	biolink:NamedThing	negative regulation of brown fat cell proliferation	Any process that stops or decreases the rate or extent of brown fat cell proliferation.	tmpzr1t_l9r_go_relaxed.owl	downregulation of brown fat cell proliferation|down regulation of brown fat cell proliferation|inhibition of brown fat cell proliferation|down-regulation of brown fat cell proliferation|negative regulation of brown adipocyte proliferation|negative regulation of brown adipose cell proliferation													biological_process											owl:Class	
GO:0035660	biolink:NamedThing	MyD88-dependent toll-like receptor 4 signaling pathway	Any series of molecular signals generated as a consequence of binding to a toll-like 4 receptor, where the MyD88 adaptor molecule mediates transduction of the signal. Toll-like 4 receptors bind bacterial lipopolysaccharide (LPS) to initiate an innate immune response.	tmpzr1t_l9r_go_relaxed.owl	MyD88-dependent toll-like receptor 4 signalling pathway|MyD88-dependent TLR4 signaling pathway							bf	2011-02-01T10:10:04Z					biological_process											owl:Class	
GO:0002755	biolink:NamedThing	MyD88-dependent toll-like receptor signaling pathway	Any series of molecular signals generated as a consequence of binding to a toll-like receptor where the MyD88 adaptor molecule mediates transduction of the signal. Toll-like receptors directly bind pattern motifs from a variety of microbial sources to initiate innate immune response.	tmpzr1t_l9r_go_relaxed.owl	MyD88-dependent toll-like receptor signalling pathway|MyD88-dependent TLR signaling pathway													biological_process											owl:Class	
GO:0035439	biolink:NamedThing	halimadienyl-diphosphate synthase activity	Catalysis of the reaction: geranylgeranyl diphosphate = halima-5(6),13-dien-15-yl diphosphate.	tmpzr1t_l9r_go_relaxed.owl	halimadienyl diphosphate synthase activity|halima-5(6),13-dien-15-yl-diphosphate lyase (cyclizing)				EC:5.5.1.16|RHEA:25621			bf	2010-04-09T02:59:35Z					molecular_function											owl:Class	
GO:0046430	biolink:NamedThing	non-phosphorylated glucose metabolic process	The chemical reactions and pathways involving non-phosphorylated forms of glucose.	tmpzr1t_l9r_go_relaxed.owl	non-phosphorylated glucose metabolism													biological_process											owl:Class	
GO:0102245	biolink:NamedThing	lupan-3beta,20-diol synthase activity	Catalysis of the reaction: lupan-3beta,20-diol <=> (S)-2,3-epoxysqualene + H2O.	tmpzr1t_l9r_go_relaxed.owl					RHEA:31351|MetaCyc:RXN-12338|EC:4.2.1.128									molecular_function											owl:Class	
GO:0048712	biolink:NamedThing	negative regulation of astrocyte differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of astrocyte differentiation.	tmpzr1t_l9r_go_relaxed.owl	downregulation of astrocyte differentiation|inhibition of astrocyte differentiation|down regulation of astrocyte differentiation|down-regulation of astrocyte differentiation													biological_process											owl:Class	
GO:0047951	biolink:NamedThing	glutathione thiolesterase activity	Catalysis of the reaction: S-acylglutathione + H(2)O = a carboxylate + glutathione + H(+).	tmpzr1t_l9r_go_relaxed.owl	citryl-glutathione thioesterhydrolase activity|glutathione thioesterase activity|S-acylglutathione hydrolase activity				RHEA:22708|KEGG_REACTION:R00547|MetaCyc:GLUTATHIONE-THIOESTERASE-RXN|EC:3.1.2.7									molecular_function											owl:Class	
GO:1904537	biolink:NamedThing	negative regulation of mitotic telomere tethering at nuclear periphery	Any process that stops, prevents or reduces the frequency, rate or extent of mitotic telomere tethering at nuclear periphery.	tmpzr1t_l9r_go_relaxed.owl	down regulation of mitotic telomere tethering at nuclear periphery|downregulation of mitotic telomere tethering at nuclear periphery|down-regulation of mitotic telomere tethering at nuclear periphery|inhibition of mitotic telomere tethering at nuclear periphery							al	2015-08-04T14:24:32Z					biological_process											owl:Class	
GO:0003293	biolink:NamedThing	heart valve cell differentiation	The process in which an endocardial cushion cell give rise to a cell that is part of a heart valve.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-10-20T11:06:46Z					biological_process											owl:Class	
GO:0001562	biolink:NamedThing	response to protozoan	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a protozoan.	tmpzr1t_l9r_go_relaxed.owl	response to protozoa|resistance to pathogenic protozoa|response to protozoon											GO:0042833		biological_process											owl:Class	
GO:0102150	biolink:NamedThing	3-oxo-myristoyl-CoA hydrolase activity	Catalysis of the reaction: 3-oxotetradecanoyl-CoA + H2O <=> 3-oxo-myristate + coenzyme A + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-11668									molecular_function											owl:Class	
GO:1901721	biolink:NamedThing	positive regulation of NMS complex assembly	Any process that activates or increases the frequency, rate or extent of NMS complex assembly. The NMS complex is involved in chromosome segregation.	tmpzr1t_l9r_go_relaxed.owl	up regulation of NMS complex interaction involved in chromosome segregation|activation of NMS complex association involved in chromosome segregation|up regulation of KMN network assembly involved in chromosome segregation|up-regulation of NMS complex interaction involved in chromosome segregation|upregulation of KMN complex interaction involved in chromosome segregation|upregulation of NMS complex interaction involved in chromosome segregation|upregulation of NMS complex association involved in chromosome segregation|positive regulation of KMN complex interaction involved in chromosome segregation|up-regulation of NMS complex association involved in chromosome segregation|up regulation of NMS complex association involved in chromosome segregation|activation of NMS complex interaction involved in chromosome segregation|positive regulation of KMN network assembly involved in chromosome segregation|up regulation of KMN complex interaction involved in chromosome segregation|positive regulation of NMS complex association involved in chromosome segregation|upregulation of KMN network assembly involved in chromosome segregation|positive regulation of NMS complex assembly involved in kinetochore assembly|up-regulation of KMN network assembly involved in chromosome segregation|activation of KMN network assembly involved in chromosome segregation|activation of KMN complex assembly involved in chromosome segregation|up-regulation of KMN complex interaction involved in chromosome segregation							jl	2012-12-20T11:44:26Z					biological_process											owl:Class	
GO:0021743	biolink:NamedThing	hypoglossal nucleus development	The process whose specific outcome is the progression of the hypoglossal nucleus over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0032131	biolink:NamedThing	alkylated DNA binding	Binding to an alkylated residue in DNA.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0102741	biolink:NamedThing	paraxanthine:S-adenosyl-L-methionine 3-N-methyltransferase activity	Catalysis of the reaction: 1,7-dimethylxanthine + S-adenosyl-L-methionine  <=> H+ + caffeine + S-adenosyl-L-homocysteine.	tmpzr1t_l9r_go_relaxed.owl					EC:2.1.1.160|MetaCyc:RXN-7601|RHEA:10280									molecular_function											owl:Class	
GO:0019595	biolink:NamedThing	non-phosphorylated glucose catabolic process	The chemical reactions and pathways resulting in the breakdown of non-phosphorylated forms of glucose.	tmpzr1t_l9r_go_relaxed.owl	non-phosphorylated glucose catabolism|non-phosphorylated glucose degradation|non-phosphorylated glucose breakdown				MetaCyc:NPGLUCAT-PWY									biological_process											owl:Class	
GO:0043824	biolink:NamedThing	succinylglutamate-semialdehyde dehydrogenase activity	Catalysis of the reaction: N-succinyl-L-glutamate 5-semialdehyde + H(2)O + NAD(+) = N-succinyl-L-glutamate + 2 H(+) + NADH.	tmpzr1t_l9r_go_relaxed.owl	AruD|SGSD|succinylglutamic semialdehyde dehydrogenase activity|N-succinyl-L-glutamate 5-semialdehyde:NAD+ oxidoreductase activity|N-succinylglutamate 5-semialdehyde dehydrogenase activity|succinyl glutamate-semialdehyde dehydrogenase activity|AstD				KEGG_REACTION:R05049|RHEA:10812|EC:1.2.1.71|MetaCyc:SUCCGLUALDDEHYD-RXN									molecular_function											owl:Class	
GO:1990917	biolink:NamedThing	ooplasm	The cytoplasm of an ovum.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-12-10T21:40:16Z					cellular_component											owl:Class	
GO:0001057	biolink:NamedThing	RNA polymerase IV activity	Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template that contains an RNA polymerase IV specific promoter to direct initiation and catalyses DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'.	tmpzr1t_l9r_go_relaxed.owl	DNA-directed RNA polymerase activity involved in transcription from RNA polymerase IV promoter							krc	2010-09-23T03:44:55Z					molecular_function											owl:Class	
GO:0090675	biolink:NamedThing	intermicrovillar adhesion	The biological adhesion process by which adjacent microvilli attach to each other through Ca(2+)-dependent adhesion links made of protocadherin-24 and mucin-like protocadherin.	tmpzr1t_l9r_go_relaxed.owl								tb	2016-02-19T13:34:07Z					biological_process											owl:Class	
GO:0060725	biolink:NamedThing	regulation of coreceptor activity	Any process that modulates the rate or frequency of coreceptor activity, combining with an extracellular or intracellular messenger, and in cooperation with a nearby primary receptor, initiating a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-06-12T01:20:11Z					biological_process											owl:Class	
GO:0086079	biolink:NamedThing	gap junction channel activity involved in Purkinje myocyte-ventricular cardiac muscle cell electrical coupling	A wide pore channel activity that enables a direct cytoplasmic connection from a Purkinje myocyte to a ventricular cardiac muscle cell. The gap junction passes electrical signals between the cells contributing to cardiac conduction.	tmpzr1t_l9r_go_relaxed.owl								dph	2011-11-22T10:36:23Z					molecular_function											owl:Class	
GO:0099098	biolink:NamedThing	microtubule polymerization based movement	The movement of a cellular component as a result of microtubule polymerization.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1903984	biolink:NamedThing	positive regulation of TRAIL-activated apoptotic signaling pathway	Any process that activates or increases the frequency, rate or extent of TRAIL-activated apoptotic signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of tumor necrosis factor-related apoptosis-inducing ligand apoptotic signaling pathway|up-regulation of TRAIL-activated extrinsic apoptotic signaling pathway|up regulation of tumor necrosis factor-related apoptosis-inducing ligand apoptotic signaling pathway|up-regulation of TRAIL-activated apoptotic signaling pathway|up regulation of TRAIL-activated extrinsic apoptotic signaling pathway|upregulation of TRAIL-induced apoptotic signaling pathway|up regulation of TRAIL-activated apoptotic signaling pathway|upregulation of TRAIL-activated apoptotic signaling pathway|activation of tumor necrosis factor-related apoptosis-inducing ligand apoptotic signaling pathway|activation of TRAIL-activated apoptotic signaling pathway|up regulation of TRAIL-induced apoptotic signaling pathway|positive regulation of TRAIL-activated extrinsic apoptotic signaling pathway|up-regulation of TRAIL-induced apoptotic signaling pathway|positive regulation of TRAIL-induced apoptotic signaling pathway|activation of TRAIL-activated extrinsic apoptotic signaling pathway|upregulation of TRAIL-activated extrinsic apoptotic signaling pathway|up-regulation of tumor necrosis factor-related apoptosis-inducing ligand apoptotic signaling pathway|upregulation of tumor necrosis factor-related apoptosis-inducing ligand apoptotic signaling pathway|activation of TRAIL-induced apoptotic signaling pathway							bf	2015-03-03T15:04:21Z					biological_process											owl:Class	
GO:0071031	biolink:NamedThing	nuclear mRNA surveillance of mRNA 3'-end processing	The set of processes involved in identifying and degrading mRNAs with incorrectly formed 3'-ends within the nucleus.	tmpzr1t_l9r_go_relaxed.owl	nuclear mRNA quality control of mRNAs with aberrant 3'-ends|nuclear mRNA catabolic process of mRNA with aberrant 3'-ends							krc	2009-07-28T04:29:17Z					biological_process											owl:Class	
GO:0071765	biolink:NamedThing	nuclear inner membrane organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear inner membrane.	tmpzr1t_l9r_go_relaxed.owl	nuclear inner membrane organisation|nuclear inner membrane organization and biogenesis							mah	2010-03-29T04:04:57Z					biological_process											owl:Class	
GO:0036401	biolink:NamedThing	pyrokinin receptor activity	Combining with a pyrokinin and transmitting the signal within the cell to induce a change in cell activity. Pyrokinins are a group of insect neuropeptides that share the common C-terminal pentapeptide sequence Phe-X-Pro-Arg-Leu-NH2 (X = S, T, K, A, or G). They play a central role in diverse physiological processes including stimulation of gut motility, production and release of sex pheromones, diapause, and pupariation.	tmpzr1t_l9r_go_relaxed.owl	PK receptor activity							bf	2013-07-18T15:10:55Z					molecular_function											owl:Class	
GO:0015124	biolink:NamedThing	allantoate transmembrane transporter activity	Enables the transfer of allantoate from one side of a membrane to the other. Allantoate is the end product of purine metabolism in mammals and some fish, formed form allantoin. It is widely distributed in plants as an important source of stored nitrogen.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0033843	biolink:NamedThing	xyloglucan 6-xylosyltransferase activity	Catalysis of the transfer of an alpha-D-xylosyl residue from UDP-D-xylose to a glucose residue in xyloglucan, forming an alpha-1,6-D-xylosyl-D-glucose linkage.	tmpzr1t_l9r_go_relaxed.owl	uridine diphosphoxylose-xyloglucan 6alpha-xylosyltransferase activity|UDP-D-xylose:xyloglucan 1,6-alpha-D-xylosyltransferase activity|xyloglucan 6-alpha-D-xylosyltransferase activity				EC:2.4.2.39|MetaCyc:2.4.2.39-RXN									molecular_function											owl:Class	
GO:0043802	biolink:NamedThing	hydrogenobyrinic acid a,c-diamide synthase (glutamine-hydrolysing) activity	Catalysis of the reaction: 2 L-glutamine + 2 ATP + 2 H(2)O + hydrogenobyrinate = 2 L-glutamate + 2 ADP + 4 H(+) + hydrogenobyrinate a,c-diamide + 2 phosphate.	tmpzr1t_l9r_go_relaxed.owl	hydrogenobyrinic acid a,c diamide synthase (glutamine-hydrolysing) activity|hydrogenobyrinic-acid:L-glutamine amido-ligase (AMP-forming)|CobB				MetaCyc:R341-RXN|EC:6.3.5.9|KEGG_REACTION:R05224|RHEA:12544									molecular_function											owl:Class	
GO:0099602	biolink:NamedThing	neurotransmitter receptor regulator activity	A molecular function that directly (via physical interaction or direct modification) activates, inhibits or otherwise modulates the activity of a neurotransmitter receptor. Modulation of activity includes changes in desensitization rate, ligand affinity, ion selectivity and pore-opening/closing.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0034945	biolink:NamedThing	2,6-dimethyl-5-methylene-3-oxo-heptanoyl-CoA C-acetyltransferase activity	Catalysis of the reaction: 2,6-dimethyl-5-methylene-3-oxo-heptanoyl-CoA + CoASH = 3-isopropylbut-3-enoyl-CoA + propanoyl-CoA.	tmpzr1t_l9r_go_relaxed.owl					EC:2.3.1.-|UM-BBD_reactionID:r0987									molecular_function											owl:Class	
GO:0034499	biolink:NamedThing	late endosome to Golgi transport	The directed movement of substances from late endosomes to the Golgi.	tmpzr1t_l9r_go_relaxed.owl	PVE to Golgi transport|prevacuolar endosome to Golgi transport													biological_process											owl:Class	
GO:0030257	biolink:NamedThing	type III protein secretion system complex	A complex of approximately 20 proteins, most of which are located in the cytoplasmic membrane that carries out protein secretion in the bacterial type III secretion system; type III secretion also requires a cytoplasmic, probably membrane-associated ATPase.	tmpzr1t_l9r_go_relaxed.owl	TTSS complex|T3SS complex													cellular_component											owl:Class	
GO:0070358	biolink:NamedThing	actin polymerization-dependent cell motility	A process involved in the controlled movement of a bacterial cell powered by the continuous polymerization of actin at one pole of the cell.	tmpzr1t_l9r_go_relaxed.owl	cell motility by actin tail formation													biological_process											owl:Class	
GO:0043515	biolink:NamedThing	kinetochore binding	Binding to a kinetochore, a proteinaceous structure on a condensed chromosome, beside the centromere, to which the spindle fibers are attached.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0097290	biolink:NamedThing	alpha-ribazole biosynthetic process	The chemical reactions and pathways resulting in the formation of alpha-ribazole, the benzimidazole nucleoside in adenosyl cobalamin (vitamin B12).	tmpzr1t_l9r_go_relaxed.owl	alpha-ribazole anabolism|alpha-ribazole formation|alpha-ribazole biosynthesis|alpha-ribazole synthesis							pr	2012-04-25T11:51:07Z					biological_process											owl:Class	
GO:1990852	biolink:NamedThing	protein transport along microtubule to spindle pole body	The directed movement of a protein along a microtubule to the spindle pole body, mediated by motor proteins.	tmpzr1t_l9r_go_relaxed.owl								vw	2015-09-15T11:09:54Z					biological_process											owl:Class	
GO:0071989	biolink:NamedThing	establishment of protein localization to spindle pole body	The directed movement of a protein to a specific location at the spindle pole body.	tmpzr1t_l9r_go_relaxed.owl	establishment of protein localisation to spindle pole body							mah	2010-10-25T11:01:17Z					biological_process											owl:Class	
GO:0102450	biolink:NamedThing	kaempferide 7-O-methyltransferase activity	Catalysis of the reaction: kaempferide + S-adenosyl-L-methionine  <=> 7,4'-dimethylkaempferol + S-adenosyl-L-homocysteine.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-13936									molecular_function											owl:Class	
GO:0071235	biolink:NamedThing	cellular response to proline	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a proline stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-12-03T02:09:45Z					biological_process											owl:Class	
GO:2001124	biolink:NamedThing	regulation of translational frameshifting	Any process that modulates the frequency, rate or extent of translational frameshifting.	tmpzr1t_l9r_go_relaxed.owl								dph	2011-10-12T05:52:22Z					biological_process											owl:Class	
GO:0042428	biolink:NamedThing	serotonin metabolic process	The chemical reactions and pathways involving serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties.	tmpzr1t_l9r_go_relaxed.owl	serotonin metabolism													biological_process											owl:Class	
GO:0140530	biolink:NamedThing	MCM complex loading	The protein localization process in which two MCM complexes become associated with chromatin at replication origins. MCM loading begins when origin-bound ORC and Cdc6 (Cdc18 in fission yeast) recruit one MCM2-7/Cdt1 complex to the origin, includes formation of a succession of intermediate complexes and ATP hydrolysis-dependent Mcm2-7 ring closure, and ends when two MCM hexamers fully encircle DNA, and are oriented head-to-head. The double hexamer is inactive for DNA unwinding. MCM loading takes place during G1 phase, and precedes CMG complex assembly.	tmpzr1t_l9r_go_relaxed.owl	MCM complex loading at replication origin|MCM double hexamer formation at replication origin	https://github.com/geneontology/go-ontology/issues/16570						pg	2020-10-12T16:46:23Z					biological_process											owl:Class	
GO:0050645	biolink:NamedThing	limonoid glucosyltransferase activity	Catalysis of the reaction: UDP-glucose + limonin = glucosyl-limonin + UDP.	tmpzr1t_l9r_go_relaxed.owl	limonoid UDP-glucosyltransferase activity|uridine diphosphoglucose-limonoid glucosyltransferase activity|LGTase activity				EC:2.4.1.210|RHEA:11256|MetaCyc:2.4.1.210-RXN									molecular_function											owl:Class	
GO:0017197	biolink:NamedThing	N-terminal peptidyl-proline acetylation	The acetylation of the N-terminal proline of proteins to form the derivative N-acetyl-L-proline.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0050									biological_process											owl:Class	
GO:0033691	biolink:NamedThing	sialic acid binding	Binding to a sialic acid, a N- or O- substituted derivative of neuraminic acid, a nine carbon monosaccharide. Sialic acids often occur in polysaccharides, glycoproteins, and glycolipids in animals and bacteria.	tmpzr1t_l9r_go_relaxed.owl	N-acetylneuraminic acid binding													molecular_function											owl:Class	
GO:0009918	biolink:NamedThing	sterol delta7 reductase activity	Catalysis of the reaction: 5-dehydroepisterol = 24-methylenecholesterol.	tmpzr1t_l9r_go_relaxed.owl	sterol delta-7 reductase activity				MetaCyc:RXN-707									molecular_function											owl:Class	
GO:0031945	biolink:NamedThing	positive regulation of glucocorticoid metabolic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving glucocorticoids.	tmpzr1t_l9r_go_relaxed.owl	activation of glucocorticoid metabolic process|positive regulation of glucocorticoid metabolism|stimulation of glucocorticoid metabolic process|up-regulation of glucocorticoid metabolic process|up regulation of glucocorticoid metabolic process|upregulation of glucocorticoid metabolic process													biological_process											owl:Class	
GO:0045658	biolink:NamedThing	regulation of neutrophil differentiation	Any process that modulates the frequency, rate or extent of neutrophil differentiation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0030957	biolink:NamedThing	Tat protein binding	Binding to Tat, a viral transactivating regulatory protein from the human immunodeficiency virus, or the equivalent protein from another virus.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0061386	biolink:NamedThing	closure of optic fissure	The closure of the temporary ventral gap in the optic cup that contributes to its shaping.	tmpzr1t_l9r_go_relaxed.owl	closure or choriod fissure							dph	2011-03-30T08:14:59Z					biological_process											owl:Class	
GO:0060936	biolink:NamedThing	cardiac fibroblast cell development	The process whose specific outcome is the progression of a cardiac fibroblast over time, from its formation to the mature state. A cardiac fibroblast is a connective tissue cell of the heart which secretes an extracellular matrix rich in collagen and other macromolecules.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-09-29T01:23:03Z					biological_process											owl:Class	
GO:0050696	biolink:NamedThing	trichloroethylene catabolic process	The chemical reactions and pathways resulting in the breakdown of trichloroethylene, a toxic, colorless, photoreactive, chlorinated hydrocarbon liquid, commonly used as a metal degreaser and solvent.	tmpzr1t_l9r_go_relaxed.owl	trichloroethylene catabolism|trichloroethene catabolism|trichloroethene catabolic process|trichloroethylene breakdown|trichloroethylene degradation													biological_process											owl:Class	
GO:0061753	biolink:NamedThing	substrate localization to autophagosome	The localization process by which an autophagic substrate is delivered to a forming autophagosome.	tmpzr1t_l9r_go_relaxed.owl	substrate sequestration to autophagosome|substrate sequestration to phagophore							dph	2015-11-20T11:14:22Z					biological_process											owl:Class	
GO:0047587	biolink:NamedThing	5-alpha-hydroxysteroid dehydratase activity	Catalysis of the reaction: 5alpha-ergosta-7,22-diene-3beta,5-diol = ergosterol + H(2)O.	tmpzr1t_l9r_go_relaxed.owl	5alpha-ergosta-7,22-diene-3beta,5-diol 5,6-hydro-lyase activity|5alpha-hydroxysteroid dehydratase activity|5alpha-ergosta-7,22-diene-3beta,5-diol 5,6-hydro-lyase (ergosterol-forming)				RHEA:22064|MetaCyc:5-ALPHA-HYDROXYSTEROID-DEHYDRATASE-RXN|EC:4.2.1.62|KEGG_REACTION:R03675									molecular_function											owl:Class	
GO:0071449	biolink:NamedThing	cellular response to lipid hydroperoxide	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipid hydroperoxide stimulus. Lipid hydroperoxide is the highly reactive primary oxygenated products of polyunsaturated fatty acids.	tmpzr1t_l9r_go_relaxed.owl	cellular response to LHPO							mah	2009-12-16T04:17:57Z					biological_process											owl:Class	
GO:0015834	biolink:NamedThing	peptidoglycan-associated peptide transport	The directed movement of peptidoglycan peptides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Peptidoglycan peptides are the oligopeptides found in peptidoglycan networks which cross-link the polysaccharide chains.	tmpzr1t_l9r_go_relaxed.owl	peptidoglycan peptide transport|muropeptide transport|murein peptide transport													biological_process											owl:Class	
GO:1904422	biolink:NamedThing	cellular response to D-galactosamine	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a D-galactosamine stimulus.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-07-02T15:38:36Z					biological_process											owl:Class	
GO:0070679	biolink:NamedThing	inositol 1,4,5 trisphosphate binding	Binding to inositol 1,4,5 trisphosphate.	tmpzr1t_l9r_go_relaxed.owl	IP3 binding|InsP3 binding							mah	2009-05-29T04:07:00Z					molecular_function											owl:Class	
GO:0043975	biolink:NamedThing	histone H3-K36 acetylation	The modification of histone H3 by the addition of an acetyl group to a lysine residue at position 36 of the histone.	tmpzr1t_l9r_go_relaxed.owl	histone H3K36 acetylation|histone H3 acetylation at K36													biological_process											owl:Class	
GO:0035857	biolink:NamedThing	eosinophil fate specification	The process involved in the specification of identity of an eosinophil cell. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment.	tmpzr1t_l9r_go_relaxed.owl	eosinophil cell fate specification							bf	2011-05-17T10:42:54Z					biological_process											owl:Class	
GO:0051005	biolink:NamedThing	negative regulation of lipoprotein lipase activity	Any process that stops or reduces the activity of the enzyme lipoprotein lipase.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of lipoprotein lipase activity|inhibition of lipoprotein lipase activity|down regulation of lipoprotein lipase activity|downregulation of lipoprotein lipase activity													biological_process											owl:Class	
GO:0033416	biolink:NamedThing	UGG codon-amino acid adaptor activity	A triplet codon-amino acid adaptor activity that recognizes a UGG codon.	tmpzr1t_l9r_go_relaxed.owl	TGG codon-amino acid adaptor activity|tryptophan tRNA					Note that in the standard genetic code, TGG codes for tryptophan.								molecular_function											owl:Class	
GO:1905757	biolink:NamedThing	negative regulation of primary cell septum biogenesis	Any process that stops, prevents or reduces the frequency, rate or extent of primary cell septum biogenesis.	tmpzr1t_l9r_go_relaxed.owl								vw	2016-12-12T18:09:59Z					biological_process											owl:Class	
GO:0009010	biolink:NamedThing	sorbitol-6-phosphate 2-dehydrogenase activity	Catalysis of the reaction: D-sorbitol 6-phosphate + NAD+ = D-fructose 6-phosphate + NADH + H+.	tmpzr1t_l9r_go_relaxed.owl	D-sorbitol-6-phosphate:NAD+ 2-oxidoreductase activity|D-glucitol-6-phosphate dehydrogenase activity|sorbitol-6-P-dehydrogenase activity|D-sorbitol-6-phosphate dehydrogenase activity|glucitol-6-phosphate dehydrogenase activity|ketosephosphate reductase activity|D-sorbitol 6-phosphate dehydrogenase activity				MetaCyc:SORB6PDEHYDROG-RXN|EC:1.1.1.140|RHEA:19837									molecular_function											owl:Class	
GO:0097414	biolink:NamedThing	classical Lewy body	Cytoplasmic inclusion, 5 to 15 micrometers in diameter, with a dense core surrounded by a halo of 10 to 20 nm wide radially oriented alpha-synuclein fibrils.	tmpzr1t_l9r_go_relaxed.owl	brainstem Lewy body				NIF_Subcellular:sao4749542545			pr	2012-11-06T16:27:41Z					cellular_component											owl:Class	
GO:1900037	biolink:NamedThing	regulation of cellular response to hypoxia	Any process that modulates the frequency, rate or extent of cellular response to hypoxia.	tmpzr1t_l9r_go_relaxed.owl	regulation of cellular response to lowered oxygen tension|regulation of cellular response to hypoxic stress							yaf	2012-01-17T09:29:03Z					biological_process											owl:Class	
GO:0039654	biolink:NamedThing	fusion of virus membrane with host endosome membrane	Fusion of a virus membrane with a host endosome membrane. Occurs after internalization of the virus through the endosomal pathway, and results in release of the virus contents into the cell.	tmpzr1t_l9r_go_relaxed.owl	fusion of virus membrane with host endosomal membrane|viral entry into host cell via caveolin-mediated endocytosis followed by membrane fusion with the endosome membrane|viral entry into host cell via endocytosis followed by membrane fusion with host endosome|viral penetration via endocytosis followed by caveolae-mediated membrane fusion with the endosome membrane|viral entry into host cell via endocytosis followed by membrane fusion with the endosome membrane|viral entry into host cell via caveolae-mediated endocytosis followed by membrane fusion with the endosome membrane|viral penetration via endocytosis followed by clathrin-mediated membrane fusion with the endosome membrane|viral entry into host cell via clathrin-mediated endocytosis followed by membrane fusion with the endosome membrane				VZ:992			bf	2013-06-20T14:24:05Z			GO:0075501|GO:0075517		biological_process											owl:Class	
GO:0043564	biolink:NamedThing	Ku70:Ku80 complex	Heterodimeric protein complex composed of a 70 kDa and a 80 kDa subunit, binds DNA through a channel formed by the heterodimer. Functions in DNA double stranded break repair, chromosome maintenance, transcription regulation, V(D)J recombination, and activation of DNA-PK.	tmpzr1t_l9r_go_relaxed.owl	Ku70:Ku80 heterodimer													cellular_component											owl:Class	
GO:0048895	biolink:NamedThing	lateral line nerve glial cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a glial cell in a lateral line nerve.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0030412	biolink:NamedThing	formimidoyltetrahydrofolate cyclodeaminase activity	Catalysis of the reaction: 5-formimidoyltetrahydrofolate + 2 H(+) = 5,10-methenyltetrahydrofolate + NH(4)(+).	tmpzr1t_l9r_go_relaxed.owl	5-formimidoyltetrahydrofolate ammonia-lyase (cyclizing; 5,10-methenyltetrahydrofolate-forming)|5-formimidoyltetrahydrofolate ammonia-lyase (cyclizing)|formiminotetrahydrofolate cyclodeaminase activity				MetaCyc:4.3.1.4-RXN|KEGG_REACTION:R02302|RHEA:22736|Reactome:R-HSA-70920|EC:4.3.1.4	Note that cyclodeaminases are lyases according to EC, whereas deaminases are hydrolases.								molecular_function											owl:Class	
GO:0047549	biolink:NamedThing	2-nitrophenol 2-monooxygenase activity	Catalysis of the reaction: 2-nitrophenol + 2 H(+) + 2 NADPH + O(2) = catechol + H(2)O + 2 NADP(+) + nitrite.	tmpzr1t_l9r_go_relaxed.owl	2-nitrophenol oxygenase activity|nitrophenol oxygenase activity|2-nitrophenol,NADPH:oxygen 2-oxidoreductase (2-hydroxylating, nitrite-forming)				EC:1.14.13.31|RHEA:19457|MetaCyc:2-NITROPHENOL-2-MONOOXYGENASE-RXN|UM-BBD_reactionID:r1494|KEGG_REACTION:R00828									molecular_function											owl:Class	
GO:1990255	biolink:NamedThing	subsynaptic reticulum organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a subsynaptic reticulum. A subsynaptic reticulum is an elaborate tubulolamellar membrane system that underlies the postsynaptic cell membrane.	tmpzr1t_l9r_go_relaxed.owl								tb	2013-12-13T23:05:21Z					biological_process											owl:Class	
GO:0090682	biolink:NamedThing	GPCR bitter taste receptor activity	A G protein-coupled receptor activity that is responsible for the sense of bitter taste.	tmpzr1t_l9r_go_relaxed.owl	G protein-coupled receptor bitter taste receptor activity|G-protein coupled receptor bitter taste receptor activity							tb	2016-05-20T15:49:18Z					molecular_function											owl:Class	
GO:0102482	biolink:NamedThing	5-deoxy-D-glucuronate isomerase activity	Catalysis of the reaction: 5-deoxy-D-glucuronate = 5-dehydro-2-deoxy-D-gluconate.	tmpzr1t_l9r_go_relaxed.owl					RHEA:25840|MetaCyc:RXN-14150|EC:5.3.1.30									molecular_function											owl:Class	
GO:0110077	biolink:NamedThing	vesicle-mediated intercellular transport	A cellular transport process in which transported substances are moved in extracellular vesicles between cells; transported substances are enclosed in the vesicle lumen or located in the extracellular vesicle membrane.	tmpzr1t_l9r_go_relaxed.owl								kmv	2018-01-29T14:46:52Z					biological_process											owl:Class	
GO:0047012	biolink:NamedThing	sterol-4-alpha-carboxylate 3-dehydrogenase (decarboxylating) activity	Catalysis of the reaction: NAD(P)+ + 3-beta-hydroxy-4-alpha-methyl-5-alpha-cholest-7-ene-4-beta-carboxylate = NAD(P)H + H+ + CO2 + 4-alpha-methyl-5-alpha-cholest-7-en-3-one.	tmpzr1t_l9r_go_relaxed.owl	3-beta-hydroxy-4-alpha-methylcholestenecarboxylate 3-dehydrogenase (decarboxylating) activity|3-beta-hydroxy-4-beta-methylcholestenoate dehydrogenase activity|sterol 4-alpha-carboxylic decarboxylase activity|3beta-hydroxy-4alpha-methylcholestenecarboxylate 3-dehydrogenase (decarboxylating)|3-beta-hydroxy-4-beta-methylcholestenecarboxylate 3-dehydrogenase (decarboxylating) activity				MetaCyc:1.1.1.170-RXN|EC:1.1.1.170									molecular_function											owl:Class	
GO:0044561	biolink:NamedThing	modulation of ion channel activity in other organism	Any process in which an organism effects a change in the frequency, rate or extent of the activity of an ion channel in another organism.	tmpzr1t_l9r_go_relaxed.owl	regulation of ion channel activity in other organism							jl	2012-04-05T03:48:28Z					biological_process											owl:Class	
GO:0035916	biolink:NamedThing	modulation of calcium channel activity in other organism	Any process in which an organism effects a change in the frequency, rate or extent of the activity of a calcium channel in another organism.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-07-01T11:51:38Z					biological_process											owl:Class	
GO:0004591	biolink:NamedThing	oxoglutarate dehydrogenase (succinyl-transferring) activity	Catalysis of the reaction: 2-oxoglutarate + lipoamide = S-succinyldihydrolipoamide + CO2.	tmpzr1t_l9r_go_relaxed.owl	alpha-ketoglutarate dehydrogenase activity|AKGDH activity|oxoglutarate dehydrogenase activity|oxoglutarate dehydrogenase (lipoamide) activity|alpha-ketoglutaric dehydrogenase activity|2-oxoglutarate:lipoamide 2-oxidoreductase (decarboxylating and acceptor-succinylating) activity|oxoglutarate decarboxylase activity|2-oxoglutarate:dihydrolipoyllysine-residue succinyltransferase-lipoyllysine 2-oxidoreductase (decarboxylating, acceptor-succinylating)|ketoglutaric dehydrogenase activity|2-oxoglutarate dehydrogenase activity|2-ketoglutarate dehydrogenase activity|alpha-ketoglutaric acid dehydrogenase activity|2-oxoglutarate: lipoate oxidoreductase activity|alpha-oxoglutarate dehydrogenase activity|OGDC activity				MetaCyc:2OXOGLUTDECARB-RXN|RHEA:12188|EC:1.2.4.2									molecular_function											owl:Class	
GO:0016624	biolink:NamedThing	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which an aldehyde or ketone (oxo) group acts as a hydrogen or electron donor and reduces a disulfide.	tmpzr1t_l9r_go_relaxed.owl	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulphide as acceptor				EC:1.2.4.-									molecular_function											owl:Class	
GO:0047238	biolink:NamedThing	glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity	Catalysis of the reaction: D-glucuronyl-N-acetyl-1,3-beta-D-galactosaminylproteoglycan + UDP-N-acetylgalactosamine = N-acetyl-D-galactosaminyl-1,4-beta-D-glucuronyl-N-acetyl-1,3-beta-D-galactosaminylproteoglycan + UDP.	tmpzr1t_l9r_go_relaxed.owl	UDP-N-acetyl-D-galactosamine:beta-D-glucuronosyl-(1->3)-N-acetyl-beta-D-galactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity|chondroitin synthase activity|UDP-N-acetyl-D-galactosamine:D-glucuronyl-N-acetyl-1,3-beta-D-galactosaminylproteoglycan beta-1,4-N-acetylgalactosaminyltransferase activity|uridine diphosphoacetylgalactosamine-chondroitin acetylgalactosaminyltransferase II activity|glucuronyl-N-acetylgalactosaminylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity|glucuronyl-N-acetylgalactosaminylproteoglycan beta-1,4-N-acetylgalactosaminyltransferase activity|N-acetylgalactosaminyltransferase II activity				Reactome:R-HSA-3595176|EC:2.4.1.175|Reactome:R-HSA-1971487|Reactome:R-HSA-1971482|Reactome:R-HSA-9632033|MetaCyc:2.4.1.175-RXN									molecular_function											owl:Class	
GO:0018388	biolink:NamedThing	N-terminal peptidyl-valine condensation with pyruvate to form N-pyruvic acid 2-iminyl-L-valine	The condensation of pyruvate through the 2-oxo group with the N-terminal valine of proteins to form the derivative N-pyruvic acid 2-iminyl-L-valine.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0275									biological_process											owl:Class	
GO:0019036	biolink:NamedThing	viral transcriptional complex	Specific locations and structures in the virus infected cell involved in transcribing the viral genome.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0102574	biolink:NamedThing	3-oxo-myristoyl-ACP hydrolase activity	Catalysis of the reaction: H2O + a 3-oxo-myristoyl-[acp] = 3-oxo-myristate + H+ + a holo-[acyl-carrier protein].	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-15280									molecular_function											owl:Class	
GO:0047032	biolink:NamedThing	3-alpha-hydroxyglycyrrhetinate dehydrogenase activity	Catalysis of the reaction: 3alpha-hydroxyglycyrrhetinate + NADP(+) = 3-oxoglycyrrhetinate + H(+) + NADPH.	tmpzr1t_l9r_go_relaxed.owl	3alpha-hydroxyglycyrrhetinate dehydrogenase activity|3alpha-hydroxyglycyrrhetinate:NADP+ 3-oxidoreductase activity				KEGG_REACTION:R04099|RHEA:20816|MetaCyc:1.1.1.230-RXN|EC:1.1.1.230									molecular_function											owl:Class	
GO:0031713	biolink:NamedThing	B2 bradykinin receptor binding	Binding to a B2 bradykinin receptor.	tmpzr1t_l9r_go_relaxed.owl	B2 bradykinin receptor ligand													molecular_function											owl:Class	
GO:1901154	biolink:NamedThing	paromomycin catabolic process	The chemical reactions and pathways resulting in the breakdown of paromomycin.	tmpzr1t_l9r_go_relaxed.owl	paromomycin degradation|paromomycin breakdown|paromomycin catabolism							yaf	2012-07-17T04:27:44Z					biological_process											owl:Class	
GO:0007499	biolink:NamedThing	ectoderm and mesoderm interaction	A cell-cell signaling process occurring between the two gastrulation-generated layers of the ectoderm and the mesoderm.	tmpzr1t_l9r_go_relaxed.owl	ectoderm/mesoderm interaction													biological_process											owl:Class	
GO:1905386	biolink:NamedThing	positive regulation of protein localization to presynapse	Any process that activates or increases the frequency, rate or extent of protein localization to presynapse.	tmpzr1t_l9r_go_relaxed.owl	activation of protein localisation in presynapse|up regulation of protein localisation in presynapse|positive regulation of protein localisation in presynapse|up-regulation of protein localization to presynapse|activation of protein localization in presynapse|positive regulation of protein localisation to presynapse|up-regulation of protein localisation to presynapse|up-regulation of protein localization in presynapse|up regulation of protein localization in presynapse|activation of recruitment of presynaptic proteins|upregulation of protein localization to presynapse|up regulation of recruitment of presynaptic proteins|upregulation of protein localisation in presynapse|up-regulation of recruitment of presynaptic proteins|upregulation of recruitment of presynaptic proteins|activation of protein localization to presynapse|up regulation of protein localisation to presynapse|activation of protein localisation to presynapse|upregulation of protein localization in presynapse|up-regulation of protein localisation in presynapse|positive regulation of recruitment of presynaptic proteins|up regulation of protein localization to presynapse|upregulation of protein localisation to presynapse|positive regulation of protein localization in presynapse							dos	2016-08-18T14:56:21Z					biological_process											owl:Class	
GO:0043105	biolink:NamedThing	negative regulation of GTP cyclohydrolase I activity	Any process that stops or reduces the activity of the enzyme GTP cyclohydrolase I.	tmpzr1t_l9r_go_relaxed.owl	inhibition of GTP cyclohydrolase I activity|down regulation of GTP cyclohydrolase I activity|downregulation of GTP cyclohydrolase I activity|down-regulation of GTP cyclohydrolase I activity													biological_process											owl:Class	
GO:0018896	biolink:NamedThing	dibenzothiophene catabolic process	The chemical reactions and pathways resulting in the breakdown of dibenzothiophene, a substance composed of two benzene rings linked by one sulfide bond and one carbon-carbon bond.	tmpzr1t_l9r_go_relaxed.owl	dibenzothiophene degradation|dibenzothiophene breakdown|dibenzothiophene catabolism				UM-BBD_pathwayID:dbt2									biological_process											owl:Class	
GO:0033378	biolink:NamedThing	establishment of protease localization to T cell secretory granule	The directed movement of a protease to a location within a secretory granule in a T cell.	tmpzr1t_l9r_go_relaxed.owl	establishment of protease localization in T cell secretory granule|establishment of protease localization in T lymphocyte secretory granule|establishment of protease localization in T-cell secretory granule|establishment of protease localisation in T cell secretory granule|establishment of protease localization in T-lymphocyte secretory granule													biological_process											owl:Class	
GO:0033376	biolink:NamedThing	establishment of protein localization to T cell secretory granule	The directed movement of a protein to a location within a secretory granule in a T cell.	tmpzr1t_l9r_go_relaxed.owl	establishment of protein localization in T-lymphocyte secretory granule|establishment of protein localization in T cell secretory granule|establishment of protein localization in T lymphocyte secretory granule|establishment of protein localisation in T cell secretory granule|establishment of protein localization in T-cell secretory granule													biological_process											owl:Class	
GO:0006185	biolink:NamedThing	dGDP biosynthetic process	The chemical reactions and pathways resulting in the formation of dGDP, deoxyguanosine diphosphate, (2'-deoxyguanosine 5'-diphosphate).	tmpzr1t_l9r_go_relaxed.owl	dGDP anabolism|dGDP synthesis|dGDP formation|dGDP biosynthesis													biological_process											owl:Class	
GO:0097322	biolink:NamedThing	7SK snRNA binding	Binding to a 7SK small nuclear RNA (7SK snRNA).	tmpzr1t_l9r_go_relaxed.owl	7SK small nuclear RNA binding							pr	2012-06-05T11:42:23Z					molecular_function											owl:Class	
GO:0048644	biolink:NamedThing	muscle organ morphogenesis	The process in which the anatomical structures of muscle are generated and organized.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0050224	biolink:NamedThing	prunasin beta-glucosidase activity	Catalysis of the reaction: (R)-prunasin + H(2)O = D-glucose + mandelonitrile.	tmpzr1t_l9r_go_relaxed.owl	prunasin hydrolase activity|prunasin b-glucosidase activity|prunasin beta-D-glucohydrolase activity				MetaCyc:PRUNASIN-BETA-GLUCOSIDASE-RXN|EC:3.2.1.118|KEGG_REACTION:R02558|RHEA:16489									molecular_function											owl:Class	
GO:0060861	biolink:NamedThing	positive regulation of floral organ abscission	Any process that increases the rate, frequency, or extent of floral organ shedding, the controlled shedding of floral organs.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-08-12T04:03:09Z					biological_process											owl:Class	
GO:0031441	biolink:NamedThing	negative regulation of mRNA 3'-end processing	Any process that stops, prevents, or reduces the frequency, rate or extent of mRNA 3'-end processing.	tmpzr1t_l9r_go_relaxed.owl	down regulation of mRNA 3'-end processing|inhibition of mRNA 3'-end processing|downregulation of mRNA 3'-end processing|down-regulation of mRNA 3'-end processing													biological_process											owl:Class	
GO:0102293	biolink:NamedThing	pheophytinase b activity	Catalysis of the reaction: pheophytin b + H2O <=> H+ + pheophorbide b + phytol.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-12686|EC:3.1.1.14									molecular_function											owl:Class	
GO:0018036	biolink:NamedThing	C-terminal peptidyl-asparagine amidation	The formation of a C-terminal peptidyl-asparagine amide by hydrolysis and oxidation of an interior Asn-Gly peptide in a secreted protein.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0083									biological_process											owl:Class	
GO:0010254	biolink:NamedThing	nectary development	The process whose specific outcome is the progression of the floral nectaries over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0052849	biolink:NamedThing	NADPH-dependent curcumin reductase activity	Catalysis of the reaction: curcumin + NADPH + H+ = dihydrocurcumin + NADP+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN0-6676|EC:1.3.1.n3			ai	2011-12-05T11:03:23Z					molecular_function											owl:Class	
GO:0015721	biolink:NamedThing	bile acid and bile salt transport	The directed movement of bile acid and bile salts into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	bile salt transport|bile acid transport													biological_process											owl:Class	
GO:2001089	biolink:NamedThing	maltotriose transport	The directed movement of a maltotrioseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl								jl	2011-09-21T01:24:26Z					biological_process											owl:Class	
GO:0018653	biolink:NamedThing	3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity	Catalysis of the reaction: 3-methyl-2-oxo-1,2-dihydroquinoline + O2 + 2 H+ + 2 e- = H2O + 6-hydroxy-3-methyl-2-oxo-1,2-dihydroquinoline.	tmpzr1t_l9r_go_relaxed.owl					EC:1.14.13.-|UM-BBD_reactionID:r0046									molecular_function											owl:Class	
GO:0003310	biolink:NamedThing	pancreatic A cell differentiation	The process in which relatively unspecialized cells acquire specialized structural and functional features of a pancreatic A cell. A pancreatic A cell is a cell in the pancreas that secretes glucagon.	tmpzr1t_l9r_go_relaxed.owl	pancreatic alpha cell differentiation							dph	2009-10-26T09:28:05Z					biological_process											owl:Class	
GO:0048273	biolink:NamedThing	mitogen-activated protein kinase p38 binding	Binding to mitogen-activated protein kinase p38, an enzyme that catalyzes the transfer of phosphate from ATP to hydroxyl side chains on proteins in response to mitogen activation.	tmpzr1t_l9r_go_relaxed.owl	MAPK p38 binding													molecular_function											owl:Class	
GO:0097297	biolink:NamedThing	activation of cysteine-type endopeptidase activity involved in execution phase of apoptosis	Any process that initiates the activity of an inactive cysteine-type endopeptidase involved in the execution phase of apoptosis.	tmpzr1t_l9r_go_relaxed.owl	activation of effector caspase activity					Note that this term should only be used to annotate gene products directly involved in the initiation or start up of an inactive cysteine-type endopeptidase activity involved in the execution phase of apoptosis (also known as an effector caspase). If the evidence provided is not sufficient to account for direct activation of this enzymatic activity, consider using the more generic terms GO:2001272 positive regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis or GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process.		pr	2012-05-02T03:23:01Z					biological_process											owl:Class	
GO:2001272	biolink:NamedThing	positive regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis	Any process that activates or increases the frequency, rate or extent of cysteine-type endopeptidase activity involved in execution phase of apoptosis.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of effector caspase activity							pr	2011-12-13T07:59:47Z					biological_process											owl:Class	
GO:0102778	biolink:NamedThing	Delta9-tetrahydrocannabinolate synthase activity	Catalysis of the reaction: cannabigerolate + O2 <=> Delta(9)-tetrahydrocannabinolic acid + hydrogen peroxide.	tmpzr1t_l9r_go_relaxed.owl					RHEA:34135|EC:1.21.3.7|MetaCyc:RXN-7854									molecular_function											owl:Class	
GO:0005307	biolink:NamedThing	choline:sodium symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: choline(out) + Na+(out) = choline(in) + Na+(in).	tmpzr1t_l9r_go_relaxed.owl	sodium/choline symporter activity													molecular_function											owl:Class	
GO:0110046	biolink:NamedThing	signal transduction involved in cell cycle switching, mitotic to meiotic cell cycle	A signal transduction process that contributes to cell cycle switching, mitotic to meiotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl								kmv	2017-08-09T12:28:08Z					biological_process											owl:Class	
GO:0002901	biolink:NamedThing	mature B cell apoptotic process	Any apoptotic process in a B cell that is mature, having left the bone marrow.	tmpzr1t_l9r_go_relaxed.owl	mature B lymphocyte apoptosis|apoptosis of mature B-lymphocytes|mature B-cell apoptosis|mature B-lymphocyte apoptosis|mature B cell apoptosis|programmed cell death, mature B lymphocytes|programmed cell death of mature B cells by apoptosis|mature B lymphocyte programmed cell death by apoptosis|programmed cell death of mature B-lymphocytes by apoptosis|mature B cell programmed cell death by apoptosis|programmed cell death of mature B lymphocytes by apoptosis|programmed cell death, mature B cells|programmed cell death, mature B-lymphocytes|apoptosis of mature B-cells|programmed cell death, mature B-cells|programmed cell death of mature B-cells by apoptosis|apoptosis of mature B lymphocytes|apoptosis of mature B cells|mature B-cell programmed cell death by apoptosis|mature B-lymphocyte programmed cell death by apoptosis													biological_process											owl:Class	
GO:0010358	biolink:NamedThing	leaf shaping	The developmental process that pertains to the organization of a leaf in three-dimensional space once the structure has initially formed.	tmpzr1t_l9r_go_relaxed.owl	leaf structural organization													biological_process											owl:Class	
GO:0052684	biolink:NamedThing	L-serine hydro-lyase (adding indole, L-tryptophan-forming) activity	Catalysis of the reaction: indole + L-serine = L-tryptophan + H2O.	tmpzr1t_l9r_go_relaxed.owl	L-serine hydro-lyase (adding indole; L-tryptophan-forming) activity|tryptophan synthase beta subunit activity				RHEA:26434|KEGG_REACTION:R00674|EC:4.2.1.122|MetaCyc:RXN0-2382									molecular_function											owl:Class	
GO:2000785	biolink:NamedThing	regulation of autophagosome assembly	Any process that modulates the frequency, rate or extent of autophagosome assembly.	tmpzr1t_l9r_go_relaxed.owl	regulation of autophagic vacuole formation|regulation of autophagosome formation|regulation of autophagosome biosynthesis|regulation of PAS formation|regulation of autophagic vacuole assembly							rl	2011-06-24T11:19:08Z					biological_process											owl:Class	
GO:0015390	biolink:NamedThing	purine-specific nucleoside:sodium symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: purine(out) + Na+(out) = nucleoside(in) + Na+(in).	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0048158	biolink:NamedThing	oogonium stage	The stage in mammalian oogenesis when the primordial germ cell is hardly distinguishable from other cortical cells of the ovary.	tmpzr1t_l9r_go_relaxed.owl	mammalian oogenesis stage 1													biological_process											owl:Class	
GO:0015089	biolink:NamedThing	high-affinity copper ion transmembrane transporter activity	Enables the transfer of a copper ions (Cu2+) from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.	tmpzr1t_l9r_go_relaxed.owl	high affinity copper transporter activity|high affinity copper ion transmembrane transporter activity													molecular_function											owl:Class	
GO:0002610	biolink:NamedThing	regulation of plasmacytoid dendritic cell antigen processing and presentation	Any process that modulates the frequency, rate, or extent of plasmacytoid dendritic cell antigen processing and presentation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0060371	biolink:NamedThing	regulation of atrial cardiac muscle cell membrane depolarization	Any process that modulates the establishment or extent of a membrane potential in the depolarizing direction away from the resting potential in an atrial cardiomyocyte.	tmpzr1t_l9r_go_relaxed.owl	atrial depolarization|regulation of atrial cardiomyocyte membrane depolarization|electrocardiogram PR interval|regulation of atrial cardiac muscle cell depolarization													biological_process											owl:Class	
GO:0080012	biolink:NamedThing	trihydroxyferuloyl spermidine O-methyltransferase activity	Catalysis of the reaction: trihydroxyferuloyl spermidine + S-adenosyl-L-methionine = dihydroxyferuloyl-sinapoyl spermidine + S-adenosyl-L-homocysteine + H+.	tmpzr1t_l9r_go_relaxed.owl	N1,N5,N10-tris-(5-hydroxyferuloyl)spermidine O-methyltransferase activity				MetaCyc:RXN-11263									molecular_function											owl:Class	
GO:0102071	biolink:NamedThing	9,10-epoxy-18-hydroxystearate hydrolase activity	Catalysis of the reaction: 9,10-epoxy-18-hydroxystearate + H2O <=> 9,10,18-trihydroxystearate.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-1065									molecular_function											owl:Class	
GO:0036057	biolink:NamedThing	slit diaphragm	A specialized cell-cell junction found between the interdigitating foot processes of the glomerular epithelium (the podocytes) in the vertebrate kidney, which is adapted for facilitating glomerular filtration.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-12-12T04:36:42Z					cellular_component											owl:Class	
GO:0140275	biolink:NamedThing	MIB complex	A mitochondrial intermembrane space bridging complex consisting of components of the MICOS complex in the inner mitochondrial membrane, the SAM complex in the outer membrane, a conserved DNAJ protein (human DNAJC11) and Metaxin 1.	tmpzr1t_l9r_go_relaxed.owl	mitochondrial intermembrane space bridging complex|mitofilin complex							pg	2018-10-01T17:10:27Z					cellular_component											owl:Class	
GO:0018141	biolink:NamedThing	peptide cross-linking via L-lysine thiazolecarboxylic acid	The chemical reactions and pathways resulting in the formation of a peptidyl cysteine-peptidyl lysine cross-link by the condensation of a cysteine thiol with the carbonyl of the preceding residue and alpha-beta dehydrogenation.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0245									biological_process											owl:Class	
GO:0120008	biolink:NamedThing	positive regulation of glutamatergic neuron differentiation	Any process that activates or increases the frequency, rate or extent of glutamatergic neuron differentiation.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/13107						krc	2017-03-01T16:35:45Z					biological_process											owl:Class	
GO:1901921	biolink:NamedThing	phosphorylation of RNA polymerase II C-terminal domain involved in recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex	Any phosphorylation of RNA polymerase II C-terminal domain that is involved in recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex.	tmpzr1t_l9r_go_relaxed.owl	CTD domain phosphorylation of RNA polymerase II involved in recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex							rb	2013-02-15T19:09:31Z					biological_process											owl:Class	
GO:0008241	biolink:NamedThing	peptidyl-dipeptidase activity	Catalysis of the release of C-terminal dipeptides from a polypeptide chain.	tmpzr1t_l9r_go_relaxed.owl					EC:3.4.15.-									molecular_function											owl:Class	
GO:0031004	biolink:NamedThing	potassium ion-transporting ATPase complex	Protein complex that carries out the reaction: ATP + H2O + K+(out) = ADP + phosphate + K+(in). It is a high affinity potassium uptake system. The E. coli complex consists of 4 proteins: KdpA is the potassium ion translocase, KdpB is the ATPase, and KdpC and KdpF seem to be involved in assembly and stabilization of the complex.	tmpzr1t_l9r_go_relaxed.owl	Kdp system complex													cellular_component											owl:Class	
GO:0090533	biolink:NamedThing	cation-transporting ATPase complex	Protein complex that carries out the reaction: ATP + H2O + cation(out) = ADP + phosphate + cation(in).	tmpzr1t_l9r_go_relaxed.owl								tb	2013-02-07T15:50:28Z					cellular_component											owl:Class	
GO:0046786	biolink:NamedThing	viral replication complex formation and maintenance	The process of organizing and assembling viral replication proteins in preparation for viral replication.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0047791	biolink:NamedThing	cucurbitacin delta23-reductase activity	Catalysis of the reaction: 23,24-dihydrocucurbitacin + NAD(P)+ = cucurbitacin + NAD(P)H + H+.	tmpzr1t_l9r_go_relaxed.owl	cucurbitacin delta(23) reductase activity|cucurbitacin D23-reductase activity|23,24-dihydrocucurbitacin:NAD(P)+ delta23-oxidoreductase activity|NAD(P)H: cucurbitacin B delta23-oxidoreductase activity				EC:1.3.1.5|MetaCyc:CUCURBITACIN-DELTA-23-REDUCTASE-RXN									molecular_function											owl:Class	
GO:0060749	biolink:NamedThing	mammary gland alveolus development	The progression of the mammary gland alveolus over time, from its formation to its mature state. The mammary gland alveolus is a sac-like structure that is found in the mature gland.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-06-22T10:52:12Z					biological_process											owl:Class	
GO:0001406	biolink:NamedThing	glycerophosphodiester transmembrane transporter activity	Enables the transfer of glycerophosphodiesters from one side of a membrane to the other. Glycerophosphodiesters are small molecules composed of glycerol-3-phosphate and an alcohol, for example, glycerophosphoinositol.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0016113	biolink:NamedThing	polyterpenoid catabolic process	The chemical reactions and pathways resulting in the breakdown of polyterpenoid compounds, terpenoids with more than eight isoprene units.	tmpzr1t_l9r_go_relaxed.owl	polyterpenoid catabolism|polyterpene catabolism|polyterpenoid degradation|polyterpenoid breakdown|polyterpene catabolic process													biological_process											owl:Class	
GO:0036265	biolink:NamedThing	RNA (guanine-N7)-methylation	The addition of a methyl group to the N7 atom in the base portion of a guanine nucleotide residue in an RNA molecule.	tmpzr1t_l9r_go_relaxed.owl								bf	2012-06-25T10:28:25Z					biological_process											owl:Class	
GO:0097239	biolink:NamedThing	positive regulation of transcription from RNA polymerase II promoter in response to methylglyoxal	Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter in response to a methylglyoxal stimulus.	tmpzr1t_l9r_go_relaxed.owl								pr	2012-02-02T12:28:46Z					biological_process											owl:Class	
GO:0102325	biolink:NamedThing	2,2',3-trihydroxybiphenyl monooxygenase activity	Catalysis of the reaction: biphenyl-2,2',3-triol + O2 + NADH + H+ <=> 2,2',3,3'-tetrahydroxybiphenyl + NAD + H2O.	tmpzr1t_l9r_go_relaxed.owl					RHEA:63516|MetaCyc:RXN-13169									molecular_function											owl:Class	
GO:0060315	biolink:NamedThing	negative regulation of ryanodine-sensitive calcium-release channel activity	Any process that decreases the activity of a ryanodine-sensitive calcium-release channel. The ryanodine-sensitive calcium-release channel catalyzes the transmembrane transfer of a calcium ion by a channel that opens when a ryanodine class ligand has been bound by the channel complex or one of its constituent parts.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0061051	biolink:NamedThing	positive regulation of cell growth involved in cardiac muscle cell development	Any process that increases the rate, frequency, or extent of the growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-02-25T01:08:08Z					biological_process											owl:Class	
GO:0033947	biolink:NamedThing	mannosylglycoprotein endo-beta-mannosidase activity	Catalysis of the hydrolysis of the alpha-D-mannosyl-(1->6)-beta-D-mannosyl-(1->4)-beta-D-N-acetylglucosaminyl-(1->4)-beta-D-N-acetylglucosaminyl sequence of glycoprotein to alpha-D-mannosyl-(1->6)-D-mannose and beta-D-N-acetylglucosaminyl-(1->4)-beta-D-N-acetylglucosaminyl sequences.	tmpzr1t_l9r_go_relaxed.owl	endo-beta-mannosidase activity				MetaCyc:3.2.1.152-RXN|EC:3.2.1.152									molecular_function											owl:Class	
GO:0046694	biolink:NamedThing	sperm incapacitation	The process in which the use of stored sperm from the first-mating male is inhibited by the seminal fluid of subsequently mating males.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1904307	biolink:NamedThing	response to desipramine	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a desipramine stimulus.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-06-10T17:00:31Z					biological_process											owl:Class	
GO:0005608	biolink:NamedThing	laminin-3 complex	A laminin complex composed of alpha1, beta2 and gamma1 polypeptide chains.	tmpzr1t_l9r_go_relaxed.owl	laminin-121 complex													cellular_component											owl:Class	
GO:1902800	biolink:NamedThing	positive regulation of phosphodiesterase I activity	Any process that activates or increases the frequency, rate or extent of phosphodiesterase I activity.	tmpzr1t_l9r_go_relaxed.owl	up regulation of exonuclease I activity|positive regulation of PDE I activity|up regulation of alkaline phosphodiesterase activity|activation of oligonucleate 5'-nucleotidohydrolase activity|positive regulation of 5' nucleotide phosphodiesterase/alkaline phosphodiesterase I activity|up-regulation of alkaline phosphodiesterase activity|positive regulation of 5'-nucleotide phosphodiesterase activity|activation of phosphodiesterase I activity|up regulation of 5' nucleotide phosphodiesterase/alkaline phosphodiesterase I activity|up-regulation of 5'-PDase activity|up regulation of 5'NPDE activity|activation of alkaline phosphodiesterase activity|up-regulation of nucleotide pyrophosphatase/phosphodiesterase I activity|up-regulation of 5'-PDE activity|up regulation of oligonucleate 5'-nucleotidohydrolase activity|positive regulation of 5'-NPDase activity|activation of 5'-PDE activity|up-regulation of 5' nucleotide phosphodiesterase/alkaline phosphodiesterase I activity|upregulation of phosphodiesterase I activity|positive regulation of oligonucleate 5'-nucleotidohydrolase activity|up-regulation of 5'NPDE activity|up regulation of 5'-NPDase activity|activation of 5'NPDE activity|up-regulation of 5'-exonuclease activity|positive regulation of 5'-exonuclease activity|upregulation of orthophosphoric diester phosphohydrolase activity|up regulation of 5'-nucleotide phosphodiesterase activity|positive regulation of 5'NPDE activity|activation of 5'-PDase activity|up regulation of 5'-PDE activity|upregulation of 5'-exonuclease activity|activation of 5' nucleotide phosphodiesterase/alkaline phosphodiesterase I activity|up regulation of 5'-exonuclease activity|upregulation of oligonucleate 5'-nucleotidohydrolase activity|up-regulation of PDE I activity|upregulation of 5'NPDE activity|activation of PDE I activity|up regulation of PDE I activity|positive regulation of 5'-PDase activity|up-regulation of oligonucleate 5'-nucleotidohydrolase activity|upregulation of exonuclease I activity|upregulation of 5'-nucleotide phosphodiesterase activity|positive regulation of nucleotide pyrophosphatase/phosphodiesterase I activity|upregulation of 5'-PDase activity|upregulation of alkaline phosphodiesterase activity|upregulation of 5'-PDE activity|activation of nucleotide pyrophosphatase/phosphodiesterase I activity|up-regulation of 5'-nucleotide phosphodiesterase activity|activation of exonuclease I activity|positive regulation of exonuclease I activity|positive regulation of orthophosphoric diester phosphohydrolase activity|upregulation of 5'-phosphodiesterase activity|upregulation of nucleotide pyrophosphatase/phosphodiesterase I activity|up-regulation of exonuclease I activity|up-regulation of 5'-phosphodiesterase activity|activation of 5'-phosphodiesterase activity|activation of 5'-NPDase activity|upregulation of 5' nucleotide phosphodiesterase/alkaline phosphodiesterase I activity|up regulation of 5'-PDase activity|positive regulation of 5'-PDE activity|activation of 5'-exonuclease activity|upregulation of 5'-NPDase activity|upregulation of PDE I activity|positive regulation of alkaline phosphodiesterase activity|positive regulation of 5'-phosphodiesterase activity|up-regulation of phosphodiesterase I activity|up regulation of phosphodiesterase I activity|up regulation of orthophosphoric diester phosphohydrolase activity|up-regulation of 5'-NPDase activity|up regulation of nucleotide pyrophosphatase/phosphodiesterase I activity|up regulation of 5'-phosphodiesterase activity|up-regulation of orthophosphoric diester phosphohydrolase activity|activation of orthophosphoric diester phosphohydrolase activity|activation of 5'-nucleotide phosphodiesterase activity							al	2014-03-25T08:55:54Z					biological_process											owl:Class	
GO:1901289	biolink:NamedThing	succinyl-CoA catabolic process	The chemical reactions and pathways resulting in the breakdown of succinyl-CoA.	tmpzr1t_l9r_go_relaxed.owl	succinyl-CoA degradation|succinyl-CoA catabolism|succinyl-CoA breakdown							yaf	2012-08-17T16:13:37Z					biological_process											owl:Class	
GO:0050512	biolink:NamedThing	lactosylceramide 4-alpha-galactosyltransferase activity	Catalysis of the reaction: beta-D-galactosyl-(1,4)-D-glucosylceramide + UDP-galactose = alpha-D-galactosyl-(1,4)-beta-D-galactosyl-(1,4)-D-glucosylceramide + UDP.	tmpzr1t_l9r_go_relaxed.owl	histo-blood group P(k) UDP-galactose activity|Gal-beta-1,4-Glc-beta-1-Cer alpha-1,4-galactosyltransferase activity|histo-blood group Pk UDP-galactose|UDP-galactose:lactosylceramide 4II-alpha-D-galactosyltransferase activity|lactosylceramide 4-a-galactosyltransferase activity|Gal-beta-(1,4)-Glc-beta-1-Cer alpha-(1,4)-galactosyltransferase activity|globotriaosylceramide/CD77 synthase activity				RHEA:11924|EC:2.4.1.228|MetaCyc:2.4.1.228-RXN									molecular_function											owl:Class	
GO:0031876	biolink:NamedThing	secretin receptor binding	Binding to a secretin receptor.	tmpzr1t_l9r_go_relaxed.owl	secretin receptor ligand													molecular_function											owl:Class	
GO:0018650	biolink:NamedThing	styrene monooxygenase activity	Catalysis of the reaction: styrene + NADPH + FADH + O2 = NADP+ + FAD+ + H2O + styrene oxide.	tmpzr1t_l9r_go_relaxed.owl					EC:1.14.13.-|UM-BBD_reactionID:r0225									molecular_function											owl:Class	
GO:1902771	biolink:NamedThing	positive regulation of choline O-acetyltransferase activity	Any process that activates or increases the frequency, rate or extent of choline O-acetyltransferase activity.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of choline acetyltransferase activity|upregulation of choline O-acetyltransferase activity|activation of CHOACTase activity|positive regulation of choline acetyltransferase activity|activation of choline acetylase activity|up regulation of choline acetylase activity|up regulation of choline acetyltransferase activity|upregulation of acetyl-CoA:choline O-acetyltransferase activity|activation of choline acetyltransferase activity|up regulation of CHOACTase activity|up regulation of choline O-acetyltransferase activity|up regulation of acetyl-CoA:choline O-acetyltransferase activity|upregulation of choline acetyltransferase activity|positive regulation of choline acetylase activity|upregulation of choline acetylase activity|positive regulation of CHOACTase activity|up-regulation of CHOACTase activity|activation of choline O-acetyltransferase activity|up-regulation of acetyl-CoA:choline O-acetyltransferase activity|up-regulation of choline O-acetyltransferase activity|upregulation of CHOACTase activity|positive regulation of acetyl-CoA:choline O-acetyltransferase activity|up-regulation of choline acetylase activity|activation of acetyl-CoA:choline O-acetyltransferase activity							mr	2014-03-11T18:58:39Z					biological_process											owl:Class	
GO:0033063	biolink:NamedThing	Rad51B-Rad51C-Rad51D-XRCC2 complex	A DNA recombinase mediator complex that contains the Rad51 paralogs RAD51B, RAD51C, RAD51D, and XRCC2, or orthologs thereof.	tmpzr1t_l9r_go_relaxed.owl	BCDX2 complex													cellular_component											owl:Class	
GO:0071233	biolink:NamedThing	cellular response to leucine	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leucine stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-12-03T02:09:26Z					biological_process											owl:Class	
GO:1990410	biolink:NamedThing	adrenomedullin receptor signaling pathway	A series of molecular signals initiated by an extracellular adrenomedullin combining with a dimeric adrenomedullin receptor on the surface of the target cell.	tmpzr1t_l9r_go_relaxed.owl	AM receptor signaling pathway					An example of a protein that could be annotated to this term is CALCRL in human (Q16602) in PMID:10882736.		bhm	2014-07-02T14:43:31Z					biological_process											owl:Class	
GO:0045019	biolink:NamedThing	negative regulation of nitric oxide biosynthetic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nitric oxide.	tmpzr1t_l9r_go_relaxed.owl	downregulation of nitric oxide biosynthetic process|negative regulation of nitric oxide biosynthesis|down-regulation of nitric oxide biosynthetic process|negative regulation of nitric oxide anabolism|down regulation of nitric oxide biosynthetic process|negative regulation of nitric oxide synthesis|inhibition of nitric oxide biosynthetic process|negative regulation of nitric oxide formation													biological_process											owl:Class	
GO:0036114	biolink:NamedThing	medium-chain fatty-acyl-CoA catabolic process	The chemical reactions and pathways resulting in the breakdown of medium-chain fatty-acyl-CoAs, any derivative of coenzyme A in which the sulfhydryl group is in a thioester linkage with a medium-chain fatty-acyl group. A medium-chain fatty acid is a fatty acid with a chain length of between C6 and C12.	tmpzr1t_l9r_go_relaxed.owl	medium-chain fatty-acyl-CoA catabolism|medium-chain fatty-acyl-CoA degradation|medium-chain fatty-acyl-CoA breakdown							bf	2012-02-15T11:23:16Z					biological_process											owl:Class	
GO:1990462	biolink:NamedThing	omegasome	Omega-shaped (as in the Greek capital letter) intracellular membrane-bounded organelle enriched in phosphatidylinositol 3-phosphate and dynamically connected to the endoplasmic reticulum. Omegasomes are the first step of the formation of autophagosomes via the phagophore assembly sites.	tmpzr1t_l9r_go_relaxed.owl								pr	2014-08-19T12:26:40Z					cellular_component											owl:Class	
GO:1902907	biolink:NamedThing	proteasome storage granule disassembly	The disaggregation of a proteasome storage granule into its constituent components.	tmpzr1t_l9r_go_relaxed.owl	PSG disassembly							di	2014-04-16T01:59:47Z					biological_process											owl:Class	
GO:0102684	biolink:NamedThing	L-phenylalanine N-monooxygenase activity	Catalysis of the reaction: L-phenylalanine  + 2 NADPH + 2 O2 + 2 H+ <=> (E)-phenylacetaldehyde oxime + 2 NADP + 3 H2O + carbon dioxide.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-4602|RHEA:33263|EC:1.14.14.40									molecular_function											owl:Class	
GO:1902936	biolink:NamedThing	phosphatidylinositol bisphosphate binding	Binding to phosphatidylinositol bisphosphate.	tmpzr1t_l9r_go_relaxed.owl						An example of this is KCNJ2 in human (P63252) in PMID:18690034 (inferred from direct assay)		bhm	2014-04-25T15:14:12Z					molecular_function											owl:Class	
GO:0001921	biolink:NamedThing	positive regulation of receptor recycling	Any process that activates or increases the frequency, rate or extent of receptor recycling.	tmpzr1t_l9r_go_relaxed.owl	stimulation of receptor recycling|up-regulation of receptor recycling|activation of receptor recycling|up regulation of receptor recycling|upregulation of receptor recycling													biological_process											owl:Class	
GO:0016938	biolink:NamedThing	kinesin I complex	A complex of two kinesin heavy chains and two kinesin light chains.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0120286	biolink:NamedThing	tryptophan sensor activity	Binding to and responding, e.g. by conformational change, to changes in the cellular level of tryptophan.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/20181						krc	2020-11-18T01:25:01Z					molecular_function											owl:Class	
GO:0044535	biolink:NamedThing	very-long-chain fatty acyl-CoA oxidase activity	Catalysis of the reaction: very-long-chain fatty acyl-CoA (C22 - C24) + O2 = trans-2,3-dehydroacyl-CoA + hydrogen peroxide.	tmpzr1t_l9r_go_relaxed.owl	very-long-chain acyl-CoA oxidase activity|VLC fatty-acyl-CoA oxidase activity|very long chain fatty-acyl-CoA oxidase activity				EC:1.3.3.-			jl	2012-03-21T02:04:42Z					molecular_function											owl:Class	
GO:0021852	biolink:NamedThing	pyramidal neuron migration to cerebral cortex	The migration of a pyramidal neuron precursor from the ventricular zone to the correct layer of the cerebral cortex.	tmpzr1t_l9r_go_relaxed.owl	pyramidal neuron migration|projection neuron migration	https://github.com/geneontology/go-ontology/issues/21476												biological_process											owl:Class	
GO:0140650	biolink:NamedThing	radial glia-guided pyramidal neuron migration	The radial migration of a pyramidal neuron along radial glial cells.	tmpzr1t_l9r_go_relaxed.owl	radial glia-dependent neuronal migration	https://github.com/geneontology/go-ontology/issues/21476						pg	2021-05-25T12:48:12Z					biological_process											owl:Class	
GO:0004796	biolink:NamedThing	thromboxane-A synthase activity	Catalysis of the reaction: prostaglandin H(2) = thromboxane A(2).	tmpzr1t_l9r_go_relaxed.owl	thromboxane synthetase activity|(5Z,13E)-(15S)-9alpha,11alpha-epidioxy-15-hydroxyprosta-5,13-dienoate isomerase activity|cytochrome P450 CYP5|(5Z,13E)-(15S)-9alpha,11alpha-epidioxy-15-hydroxyprosta-5,13-dienoate thromboxane-A2-isomerase activity|thromboxane synthase activity				KEGG_REACTION:R02268|RHEA:17137|Reactome:R-HSA-5603275|EC:5.3.99.5|MetaCyc:THROMBOXANE-A-SYNTHASE-RXN|Reactome:R-HSA-76500							GO:0008400		molecular_function											owl:Class	
GO:0050547	biolink:NamedThing	vanillin synthase activity	Catalysis of the reaction: 3-hydroxy-3-(4-hydroxy-3-methoxyphenyl)propanoyl-CoA = acetyl-CoA + vanillin.	tmpzr1t_l9r_go_relaxed.owl	3-hydroxy-3-(4-hydroxy-3-methoxyphenyl)propanoyl-CoA vanillin-lyase (acetyl-CoA-forming)|3-hydroxy-3-(4-hydroxy-3-methoxyphenyl)propionyl-CoA:vanillin lyase (acetyl-CoA-forming)				KEGG_REACTION:R05773|MetaCyc:4.1.2.41-RXN|EC:4.1.2.61|RHEA:18725									molecular_function											owl:Class	
GO:0046397	biolink:NamedThing	galacturonate catabolic process	The chemical reactions and pathways resulting in the breakdown of galacturonate, the anion of galacturonic acid.	tmpzr1t_l9r_go_relaxed.owl	galacturonate breakdown|galacturonate catabolism|galacturonate degradation											GO:0019587		biological_process											owl:Class	
GO:0045103	biolink:NamedThing	intermediate filament-based process	Any cellular process that depends upon or alters the intermediate filament cytoskeleton, that part of the cytoskeleton comprising intermediate filaments and their associated proteins.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1902620	biolink:NamedThing	positive regulation of microtubule minus-end binding	Any process that activates or increases the frequency, rate or extent of microtubule minus-end binding.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of microtubule minus-end binding|activation of microtubule minus-end binding|up regulation of microtubule minus-end binding|upregulation of microtubule minus-end binding							tb	2014-01-14T22:17:25Z					biological_process											owl:Class	
GO:0052200	biolink:NamedThing	response to host defenses	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detecting the defenses of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	maintenance of symbiont tolerance to host defense molecules|response to host defense molecules|response of symbiont to host defense molecules	https://github.com/geneontology/go-ontology/issues/18827|https://github.com/geneontology/go-ontology/issues/18951				Note that this term is used to annotate gene products of the symbiont.						GO:0075140|GO:0075145		biological_process											owl:Class	
GO:0052173	biolink:NamedThing	response to defenses of other organism	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detecting the defenses of another organism.	tmpzr1t_l9r_go_relaxed.owl	response to defenses of other organism during symbiotic interaction|response to defenses of other organism involved in symbiotic interaction	https://github.com/geneontology/go-ontology/issues/17930												biological_process											owl:Class	
GO:0030921	biolink:NamedThing	peptidyl-tyrosine dehydrogenation to form (Z)-2,3-didehydrotyrosine	The oxidation of the C alpha-C beta bond of peptidyl-tyrosine to form peptidyl-(Z)-2,3-didehydrotyrosine coupled with cyclization of neighboring residues.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0183									biological_process											owl:Class	
GO:1990317	biolink:NamedThing	Gin4 complex	A protein complex involved in septin ring formation during mitosis. In Saccharomyces cerevisiae it consists of BNI5, CDC3, CDC10, CDC11, CDC12, GIN4, NAP1 and SHS1. At least 2 GIN4 molecules are involved.	tmpzr1t_l9r_go_relaxed.owl	Gin4-septin complex							bhm	2014-03-14T12:07:05Z					cellular_component											owl:Class	
GO:0036240	biolink:NamedThing	septal periplasm	The region between the plasma membrane and the cell wall, as found in organisms such as filamentous fungi.	tmpzr1t_l9r_go_relaxed.owl	cell wall-enclosed septal periplasm							bf	2012-05-23T10:18:09Z					cellular_component											owl:Class	
GO:0007568	biolink:NamedThing	aging	A developmental process that is a deterioration and loss of function over time. Aging includes loss of functions such as resistance to disease, homeostasis, and fertility, as well as wear and tear. Aging includes cellular senescence, but is more inclusive. May precede death and may succeed developmental maturation (GO:0021700).	tmpzr1t_l9r_go_relaxed.owl	ageing				Wikipedia:Aging							GO:0016280		biological_process											owl:Class	
GO:0032372	biolink:NamedThing	negative regulation of sterol transport	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of sterols into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	downregulation of sterol transport|down-regulation of sterol transport|down regulation of sterol transport|inhibition of sterol transport													biological_process											owl:Class	
GO:0019678	biolink:NamedThing	propionate metabolic process, methylmalonyl pathway	The chemical reactions and pathways involving propionate that occur in the methylmalonyl pathway.	tmpzr1t_l9r_go_relaxed.owl	propionate metabolism, methylmalonyl pathway				MetaCyc:PROPIONMET-PWY									biological_process											owl:Class	
GO:0102971	biolink:NamedThing	phosphinothricin N-acetyltransferase activity	Catalysis of the reaction: acetyl-CoA + phosphinothricin <=> H+ + coenzyme A(4-) + N-acetylphosphinatothricinate.	tmpzr1t_l9r_go_relaxed.owl					RHEA:12597|EC:2.3.1.183|MetaCyc:RXN-9382									molecular_function											owl:Class	
GO:0060736	biolink:NamedThing	prostate gland growth	The increase in size or mass of the prostate gland where the increase in size or mass has the specific outcome of the progression of the gland, from its formation to its mature state.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-06-15T09:21:52Z					biological_process											owl:Class	
GO:2000814	biolink:NamedThing	positive regulation of barbed-end actin filament capping	Any process that activates or increases the frequency, rate or extent of barbed-end actin filament capping.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of barbed-end F-actin capping activity|positive regulation of barbed-end actin capping activity|positive regulation of plus-end F-actin capping activity|positive regulation of plus-end actin filament capping activity							rl	2011-07-07T04:08:23Z					biological_process											owl:Class	
GO:0061435	biolink:NamedThing	positive regulation of transcription from a mobile element promoter	Any process that activates or increases the frequency, rate or extent of transcription from a mobile element promoter.	tmpzr1t_l9r_go_relaxed.owl								dph	2012-02-09T10:01:33Z					biological_process											owl:Class	
GO:0033757	biolink:NamedThing	glucoside 3-dehydrogenase activity	Catalysis of the reaction: sucrose + acceptor = 3-dehydro-alpha-D-glucosyl-beta-D-fructofuranoside + reduced acceptor.	tmpzr1t_l9r_go_relaxed.owl	D-aldohexoside:(acceptor) 3-oxidoreductase|D-aldohexopyranoside dehydrogenase|D-aldohexoside:cytochrome c oxidoreductase|D-aldohexoside:acceptor 3-oxidoreductase|hexopyranoside-cytochrome c oxidoreductase				RHEA:16589|MetaCyc:GLUCOSIDE-3-DEHYDROGENASE-RXN|EC:1.1.99.13|Wikipedia:Glucoside_3-dehydrogenase									molecular_function											owl:Class	
GO:1990168	biolink:NamedThing	protein K33-linked deubiquitination	A protein deubiquitination process in which a K33-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 33 of the ubiquitin monomers, is removed from a protein.	tmpzr1t_l9r_go_relaxed.owl								sp	2013-08-14T11:19:39Z					biological_process											owl:Class	
GO:1904425	biolink:NamedThing	negative regulation of GTP binding	Any process that stops, prevents or reduces the frequency, rate or extent of GTP binding.	tmpzr1t_l9r_go_relaxed.owl	inhibition of GTP binding|down regulation of GTP binding|downregulation of GTP binding|down-regulation of GTP binding							sl	2015-07-02T20:35:01Z					biological_process											owl:Class	
GO:0046289	biolink:NamedThing	isoflavonoid phytoalexin metabolic process	The chemical reactions and pathways involving isoflavonoid phytoalexins, a group of water-soluble phenolic derivatives isomeric with flavonoids that possess antibiotic activity and are produced by plant tissues in response to infection.	tmpzr1t_l9r_go_relaxed.owl	isoflavonoid phytoalexin metabolism													biological_process											owl:Class	
GO:0009258	biolink:NamedThing	10-formyltetrahydrofolate catabolic process	The chemical reactions and pathways resulting in the breakdown of 10-formyltetrahydrofolate, the formylated derivative of tetrahydrofolate.	tmpzr1t_l9r_go_relaxed.owl	10-formyl-THF catabolic process|10-formyltetrahydrofolate breakdown|10-formyltetrahydrofolate degradation|10-formyl-THF catabolism|10-formyltetrahydrofolate catabolism													biological_process											owl:Class	
GO:0103027	biolink:NamedThing	FMN phosphatase activity	Catalysis of the reaction: FMN + H2O = riboflavin + hydrogenphosphate.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN0-5187									molecular_function											owl:Class	
GO:0050348	biolink:NamedThing	trehalose O-mycolyltransferase activity	Catalysis of the reaction: 2 alpha,alpha'-trehalose 6-mycolate = alpha,alpha'-trehalose 6,6'-bismycolate + alpha,alpha-trehalose.	tmpzr1t_l9r_go_relaxed.owl	alpha,alpha'-trehalose-6-mycolate:alpha,alpha'-trehalose-6-mycolate 6'-mycolyltransferase activity|alpha,alpha'-trehalose 6-monomycolate:alpha,alpha'-trehalose mycolyltransferase activity				KEGG_REACTION:R07248|RHEA:23472|MetaCyc:RXN1G-874|EC:2.3.1.122									molecular_function											owl:Class	
GO:0004096	biolink:NamedThing	catalase activity	Catalysis of the reaction: 2 hydrogen peroxide = O2 + 2 H2O.	tmpzr1t_l9r_go_relaxed.owl	haem catalase activity|bacterial catalase-peroxidase activity|CAT|caperase activity|catalase-peroxidase activity|equilase activity|hydrogen-peroxide:hydrogen-peroxide oxidoreductase activity|optidase activity|heme catalase activity|catalase reaction|manganese catalase activity				UM-BBD_enzymeID:e0834|Reactome:R-HSA-76031|Reactome:R-HSA-1222704|EC:1.11.1.6|RHEA:20309|MetaCyc:CATAL-RXN							GO:0016952|GO:0016953		molecular_function											owl:Class	
GO:0099055	biolink:NamedThing	integral component of postsynaptic membrane	The component of the postsynaptic membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0048495	biolink:NamedThing	Roundabout binding	Binding to Roundabout (ROBO) receptor, a transmembrane receptor.	tmpzr1t_l9r_go_relaxed.owl	Roundabout receptor binding													molecular_function											owl:Class	
GO:0090078	biolink:NamedThing	smooth muscle derived foam cell differentiation	The process in which a smooth muscle cell acquires the specialized features of a foam cell. A foam cell is a type of cell containing lipids in small vacuoles and typically seen in atherosclerotic lesions, as well as other conditions.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-09-15T03:48:10Z					biological_process											owl:Class	
GO:0090077	biolink:NamedThing	foam cell differentiation	The process in which a relatively unspecialized cell acquires the specialized features of a foam cell. A foam cell is a type of cell containing lipids in small vacuoles and typically seen in atherosclerotic lesions, as well as other conditions.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-09-15T03:46:30Z					biological_process											owl:Class	
GO:0048490	biolink:NamedThing	anterograde synaptic vesicle transport	The directed movement of synaptic vesicle along axonal microtubules from the cell body to the presynapse.	tmpzr1t_l9r_go_relaxed.owl	anterograde axonal transport of synaptic vesicle													biological_process											owl:Class	
GO:0044172	biolink:NamedThing	host cell endoplasmic reticulum-Golgi intermediate compartment	A complex system of membrane-bounded compartments located between host cell endoplasmic reticulum (ER) and the host Golgi complex, with a distinctive membrane protein composition; involved in ER-to-Golgi transport.	tmpzr1t_l9r_go_relaxed.owl	host cell ER-Golgi intermediate compartment|host ER-Golgi intermediate compartment							jl	2009-09-04T02:44:07Z					cellular_component											owl:Class	
GO:0047021	biolink:NamedThing	15-hydroxyprostaglandin dehydrogenase (NADP+) activity	Catalysis of the reaction: NADP(+) + prostaglandin E(1) = 15-dehydro-prostaglandin E1 + H(+) + NADPH.	tmpzr1t_l9r_go_relaxed.owl	type II 15-hydroxyprostaglandin dehydrogenase activity|NADP-linked 15-hydroxyprostaglandin dehydrogenase|NADP-specific 15-hydroxyprostaglandin dehydrogenase|(13E)-(15S)-11alpha,15-dihydroxy-9-oxoprost-13-enoate:NADP+ 15-oxidoreductase activity|NADP-dependent 15-hydroxyprostaglandin dehydrogenase				MetaCyc:1.1.1.197-RXN|KEGG_REACTION:R04552|EC:1.1.1.197|RHEA:11636									molecular_function											owl:Class	
GO:0075189	biolink:NamedThing	positive regulation of hyphopodium formation	Any process that activates or increases the frequency, rate or extent of symbiont hyphopodium formation on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of hyphopodium formation on or near host													biological_process											owl:Class	
GO:0070143	biolink:NamedThing	mitochondrial alanyl-tRNA aminoacylation	The process of coupling alanine to alanyl-tRNA in a mitochondrion, catalyzed by alanyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0019345	biolink:NamedThing	cysteine biosynthetic process via S-sulfo-L-cysteine	The chemical reactions and pathways resulting in the formation of cysteine, via the intermediate S-sulfo-L-cysteine.	tmpzr1t_l9r_go_relaxed.owl	cysteine synthesis via S-sulfo-L-cysteine|cysteine biosynthetic process via S-sulpho-L-cysteine|cysteine biosynthesis via S-sulpho-L-cysteine|cysteine formation via S-sulfo-L-cysteine|cysteine anabolism via S-sulfo-L-cysteine													biological_process											owl:Class	
GO:0019344	biolink:NamedThing	cysteine biosynthetic process	The chemical reactions and pathways resulting in the formation of cysteine, 2-amino-3-mercaptopropanoic acid.	tmpzr1t_l9r_go_relaxed.owl	cysteine synthesis|cysteine biosynthesis|cysteine formation|cysteine anabolism													biological_process											owl:Class	
GO:0004814	biolink:NamedThing	arginine-tRNA ligase activity	Catalysis of the reaction: ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).	tmpzr1t_l9r_go_relaxed.owl	arginyl-transfer ribonucleate synthetase activity|arginine-tRNA synthetase activity|arginine translase activity|arginyl-transfer RNA synthetase activity|L-arginine:tRNAArg ligase (AMP-forming)|arginyl transfer ribonucleic acid synthetase activity|arginyl-tRNA synthetase activity				RHEA:20301|Reactome:R-HSA-380224|Reactome:R-HSA-379993|MetaCyc:ARGININE--TRNA-LIGASE-RXN|EC:6.1.1.19									molecular_function											owl:Class	
GO:0004361	biolink:NamedThing	glutaryl-CoA dehydrogenase activity	Catalysis of the reaction: glutaryl-CoA + acceptor = crotonoyl-CoA + CO2 + reduced acceptor.	tmpzr1t_l9r_go_relaxed.owl	glutaryl-CoA:acceptor 2,3-oxidoreductase (decarboxylating)|glutaryl-CoA:(acceptor) 2,3-oxidoreductase (decarboxylating)|glutaryl coenzyme A dehydrogenase activity				Reactome:R-HSA-71046|MetaCyc:GLUTARYL-COA-DEHYDROGENASE-RXN|UM-BBD_reactionID:r0198|EC:1.3.8.6|RHEA:13389									molecular_function											owl:Class	
GO:0120301	biolink:NamedThing	histone lactyltransferase activity	Catalysis of the reaction: (L-lysyl-[histone] + lactoyl-CoA = CoA + H(+) + N(6)-lactoyl-L-lysyl-[histone].	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/20685						krc	2021-01-19T03:38:56Z					molecular_function											owl:Class	
GO:0120300	biolink:NamedThing	peptide lactyltransferase activity	Catalysis of the reaction: (L-lysyl-[protein] + lactoyl-CoA = CoA + H(+) + N(6)-lactoyl-L-lysyl-[protein].	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/20685			RHEA:61996			krc	2021-01-19T03:35:54Z					molecular_function											owl:Class	
GO:2000812	biolink:NamedThing	regulation of barbed-end actin filament capping	Any process that modulates the frequency, rate or extent of barbed-end actin filament capping.	tmpzr1t_l9r_go_relaxed.owl	regulation of barbed-end F-actin capping activity|regulation of plus-end actin filament capping activity|regulation of plus-end F-actin capping activity|regulation of barbed-end actin capping activity							rl	2011-07-07T04:08:13Z					biological_process											owl:Class	
GO:1990215	biolink:NamedThing	negative regulation by symbiont of host intracellular transport	Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of intracellular transport in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl								ml	2013-10-10T15:42:22Z					biological_process											owl:Class	
GO:0097086	biolink:NamedThing	amniotic stem cell differentiation	The process whereby a relatively unspecialized cell acquires specialized features of an amniotic stem cell. An amniotic stem cell is a mesenchymal stem cell extracted from amniotic fluid. Amniotic stem cells are able to differentiate into various tissue types such as skin, cartilage, cardiac tissue, nerves, muscle, and bone.	tmpzr1t_l9r_go_relaxed.owl								pr	2011-06-22T11:17:52Z					biological_process											owl:Class	
GO:0003200	biolink:NamedThing	endocardial cushion to mesenchymal transition involved in heart chamber septation	A transition where an endocardial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell that will contribute to the formation of the heart septum.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-10-08T01:34:31Z					biological_process											owl:Class	
GO:0051358	biolink:NamedThing	peptide cross-linking via 2-imino-glutamic acid 5-imidazolinone glycine	The formation of the non-fluorescent protein chromophore cross-link from the alpha-carboxyl carbon of residue n, a glutamic acid, to the alpha-amino nitrogen of residue n+2, a glycine, and a dehydration to form a double bond to the alpha-amino nitrogen of residue n+1. This cross-linking is coupled with a dehydrogenation of residue n+1 to form a double bond between the alpha and beta carbons. This modification is found in the GFP-like non-fluorescent red chromoprotein from the sea anemone Radianthus macrodactylus.	tmpzr1t_l9r_go_relaxed.owl	biosynthesis of protein-protein cross-link via 2-imino-glutamic acid 5-imidazolinone glycine|biosynthetic process of protein-protein cross-link via 2-imino-glutamic acid 5-imidazolinone glycine				RESID:AA0378	See also the biological process term 'peptidyl-tyrosine dehydrogenation ; GO:0018251'.								biological_process											owl:Class	
GO:0034292	biolink:NamedThing	pinholin activity	A compound function consisting of the regulated formation of a pore via oligomerisation of an existing pool of subunits in the plasma membrane.  The resulting ion channel activity indirectly allows endolysin (murein hydrolyases) to access their cell wall substrate by collapsing the proton motive force (PMF) across the membrane, allowing the endolysin to fold to an active form and hydrolyze bonds in the peptidoglycan cell wall.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0004720	biolink:NamedThing	protein-lysine 6-oxidase activity	Catalysis of the reaction: peptidyl-L-lysyl-peptide + H2O + O2 = peptidyl-allysyl-peptide + NH3 + hydrogen peroxide.	tmpzr1t_l9r_go_relaxed.owl	lysyl oxidase activity|protein-L-lysine:oxygen 6-oxidoreductase (deaminating)				EC:1.4.3.13|Reactome:R-HSA-2129375|Reactome:R-HSA-2002466|Reactome:R-HSA-2395340|RHEA:24544|MetaCyc:PROTEIN-LYSINE-6-OXIDASE-RXN							GO:0018056		molecular_function											owl:Class	
GO:0004165	biolink:NamedThing	dodecenoyl-CoA delta-isomerase activity	Catalysis of the reaction: 3-cis-dodecenoyl-CoA = 2-trans-dodecenoyl-CoA.	tmpzr1t_l9r_go_relaxed.owl	dodecenoyl-CoA isomerase activity|dodecenoyl-CoA delta3-cis-delta2-trans-isomerase activity|3,2-trans-enoyl-CoA isomerase activity|acetylene-allene isomerase activity|dodecenoyl-CoA D-isomerase activity|delta(3),Delta(2)-enoyl-CoA isomerase activity|delta3,Delta2-enoyl-CoA isomerase activity|dodecenoyl-CoA (3Z)-(2E)-isomerase activity|delta(3)-cis-Delta(2)-trans-enoyl-CoA isomerase activity|delta3-cis-delta2-trans-enoyl-CoA isomerase				RHEA:23716|MetaCyc:ENOYL-COA-DELTA-ISOM-RXN|Reactome:R-HSA-6809808|Reactome:R-HSA-109338|EC:5.3.3.8							GO:0008461		molecular_function											owl:Class	
GO:0048179	biolink:NamedThing	activin receptor complex	A protein complex that acts as an activin receptor. Heterodimeric activin receptors, comprising one Type I activin receptor and one Type II receptor polypeptide, and heterotrimeric receptors have been observed.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0035737	biolink:NamedThing	injection of substance in to other organism	The process of forcing a substance into another organism, either by penetrating the skin of the other organism or by applying the substance externally to a sensitive tissue such as those that surround the eyes.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-03-17T10:58:57Z					biological_process											owl:Class	
GO:0021776	biolink:NamedThing	smoothened signaling pathway involved in spinal cord motor neuron cell fate specification	The series of molecular signals initiated by binding of a ligand to the transmembrane receptor smoothened in a precursor cell in the spinal cord that contributes to the process of a precursor cell becoming capable of differentiating autonomously into a motor neuron in an environment that is neutral with respect to the developmental pathway.	tmpzr1t_l9r_go_relaxed.owl	smoothened signalling pathway involved in spinal cord motor neuron cell fate specification|hh signaling pathway involved in spinal cord motor neuron cell fate specification|hedgehog signaling pathway involved in spinal cord motor neuron cell fate specification													biological_process											owl:Class	
GO:0140406	biolink:NamedThing	L-alanine export across the plasma membrane	The directed movement of L-alanine from inside of a cell, across the plasma membrane and into the extracellular region.	tmpzr1t_l9r_go_relaxed.owl								pg	2019-12-11T14:13:07Z					biological_process											owl:Class	
GO:0098982	biolink:NamedThing	GABA-ergic synapse	A synapse that uses GABA as a neurotransmitter.  These synapses are typically inhibitory.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0010346	biolink:NamedThing	shoot axis formation	The process that gives rise to a shoot axis. This process pertains to the initial formation of a structure from unspecified parts.	tmpzr1t_l9r_go_relaxed.owl	shoot formation													biological_process											owl:Class	
GO:0000038	biolink:NamedThing	very long-chain fatty acid metabolic process	The chemical reactions and pathways involving a fatty acid which has a chain length greater than C22.	tmpzr1t_l9r_go_relaxed.owl	very-long-chain fatty acid metabolic process|very-long-chain fatty acid metabolism|very long chain fatty acid metabolic process													biological_process											owl:Class	
GO:0010967	biolink:NamedThing	regulation of polyamine biosynthetic process	Any process that modulates the frequency, rate or extent of polyamine biosynthesis. Polyamine biosynthesis is the chemical reactions and pathways resulting in the formation of polyamines, any organic compound containing two or more amino groups.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-05-20T11:45:37Z					biological_process											owl:Class	
GO:0009001	biolink:NamedThing	serine O-acetyltransferase activity	Catalysis of the reaction: L-serine + acetyl-CoA = O-acetyl-L-serine + CoA.	tmpzr1t_l9r_go_relaxed.owl	acetyl-CoA:L-serine O-acetyltransferase activity|SATase activity|serine acetyltransferase activity|serine transacetylase activity|L-serine acetyltransferase activity				EC:2.3.1.30|KEGG_REACTION:R00586|MetaCyc:SERINE-O-ACETTRAN-RXN|RHEA:24560									molecular_function											owl:Class	
GO:0098875	biolink:NamedThing	epididymosome	A microvesicle of the epididymal fluid, from which spermatozoa aquire membrane proteins.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0050157	biolink:NamedThing	ornithine racemase activity	Catalysis of the reaction: L-ornithine = D-ornithine.	tmpzr1t_l9r_go_relaxed.owl					RHEA:11584|MetaCyc:ORNITHINE-RACEMASE-RXN|EC:5.1.1.12									molecular_function											owl:Class	
GO:0070140	biolink:NamedThing	SUMO-specific isopeptidase activity	Catalysis of the hydrolysis of an isopeptide bond between the small conjugating protein SUMO and a protein to which SUMO has been conjugated.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1904347	biolink:NamedThing	regulation of small intestine smooth muscle contraction	Any process that modulates the frequency, rate or extent of small intestine smooth muscle contraction.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-06-11T21:37:34Z					biological_process											owl:Class	
GO:0102086	biolink:NamedThing	N-vanillate-L-glutamate synthetase activity	Catalysis of the reaction: vanillate + L-glutamate(1-) + ATP <=> H+ + N-vanillate-L-glutamate + AMP + diphosphoric acid.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-10885									molecular_function											owl:Class	
GO:0000418	biolink:NamedThing	RNA polymerase IV complex	RNA polymerase IV is a multisubunit RNA polymerase complex found in the nucleus of plants and involved in accumulation of siRNAs and in DNA methylation-dependent silencing of endogenous repeated sequences. Pol IV is composed of subunits that are paralogous or identical to the 12 subunits of Pol II. The largest and second-largest subunits of Pol IV are the catalytic subunits and share similarity with the corresponding subunits of other eukaryotic and bacterial multisubunit RNA polymerases. The second largest subunit is also found in RNA polymerase V, while the largest subunit is found only in RNAP IV complex.	tmpzr1t_l9r_go_relaxed.owl	DNA-directed RNA polymerase IV complex|DNA-directed RNA polymerase IVa complex											GO:0000420		cellular_component											owl:Class	
GO:0033450	biolink:NamedThing	GUC codon-amino acid adaptor activity	A triplet codon-amino acid adaptor activity that recognizes a GUC codon.	tmpzr1t_l9r_go_relaxed.owl	GTC codon-amino acid adaptor activity|valine tRNA					Note that in the standard genetic code, GTC codes for valine.								molecular_function											owl:Class	
GO:0050378	biolink:NamedThing	UDP-glucuronate 4-epimerase activity	Catalysis of the reaction: UDP-alpha-D-glucuronate = UDP-alpha-D-galacturonate.	tmpzr1t_l9r_go_relaxed.owl	uridine diphosphoglucuronate epimerase activity|UDP-D-galacturonic acid 4-epimerase activity|UDPglucuronate 4-epimerase activity|UDP glucuronic epimerase activity|uridine diphospho-D-galacturonic acid|UDP-galacturonate 4-epimerase activity|uridine diphosphoglucuronic epimerase activity				RHEA:11404|KEGG_REACTION:R01385|EC:5.1.3.6|MetaCyc:UDP-GLUCURONATE-4-EPIMERASE-RXN|MetaCyc:PWY-4861									molecular_function											owl:Class	
GO:0030698	biolink:NamedThing	5,10-methylenetetrahydrofolate-dependent tRNA (m5U54) methyltransferase activity	Catalysis of the transfer of a methyl group from 5,10-methylenetetrahydrofolate to the C5 atom of the uridine residue at position 54 in a tRNA molecule. This occurs in most Gram-positive bacteria and some Gram-negative bacteria.	tmpzr1t_l9r_go_relaxed.owl	RUMT													molecular_function											owl:Class	
GO:0030696	biolink:NamedThing	tRNA (m5U54) methyltransferase activity	Catalysis of the transfer of a methyl group from a donor to the C5 atom of the uridine residue at position 54 in a tRNA molecule.	tmpzr1t_l9r_go_relaxed.owl	RUMT					Note that the term name mentions a specific position within a tRNA because no other names have yet arisen for this activity, and because the position is conserved in nearly all tRNAs. The term nevertheless can be used for activities that methylase an analogous residue at a position other than 54, if such is found, and synonyms that mention positions applicable to other tRNAs or species may also be added.								molecular_function											owl:Class	
GO:0097602	biolink:NamedThing	cullin family protein binding	Binding to a member of the cullin family, hydrophobic proteins that act as scaffolds for ubiquitin ligases (E3).	tmpzr1t_l9r_go_relaxed.owl	cullin binding							pr	2014-05-11T20:41:10Z					molecular_function											owl:Class	
GO:0050693	biolink:NamedThing	LBD domain binding	Binding to a protein's ligand binding domain (LBD) domain, found in nuclear receptors. In general, the LBDs consist of three layers comprised of twelve alpha-helices and several beta-strands that are organized around a lipophilic ligand-binding pocket.	tmpzr1t_l9r_go_relaxed.owl	ligand binding domain binding													molecular_function											owl:Class	
GO:1990044	biolink:NamedThing	protein localization to lipid droplet	A process in which a protein is transported to, or maintained in, a location on or within a lipid droplet.	tmpzr1t_l9r_go_relaxed.owl	protein localization to lipid body|protein localisation to adiposome|protein localisation to lipid particle|protein localization to adiposome|protein localization to lipid particle|protein localisation to lipid droplet|protein localisation to lipid body							sart	2013-02-15T12:40:57Z					biological_process											owl:Class	
GO:0008212	biolink:NamedThing	mineralocorticoid metabolic process	The chemical reactions and pathways involving mineralocorticoids, hormonal C21 corticosteroids synthesized from cholesterol. Mineralocorticoids act primarily on water and electrolyte balance.	tmpzr1t_l9r_go_relaxed.owl	mineralocorticoid metabolism													biological_process											owl:Class	
GO:0003917	biolink:NamedThing	DNA topoisomerase type I (single strand cut, ATP-independent) activity	Catalysis of a DNA topological transformation by transiently cleaving one DNA strand at a time to allow passage of another strand; changes the linking number by +1 per catalytic cycle.	tmpzr1t_l9r_go_relaxed.owl	untwisting enzyme activity|relaxing enzyme activity|type I DNA topoisomerase activity|type I topoisomerase activity|DNA topoisomerase I activity|deoxyribonucleate topoisomerase|topoisomerase|swivelase activity|omega-protein activity|nicking-closing enzyme activity				MetaCyc:5.99.1.2-RXN|EC:5.6.2.1	Note that a further distinction, between type IA and type IB topoisomerases, is based on sequence or structural similarity between gene products that possess type I catalytic activity.								molecular_function											owl:Class	
GO:0102371	biolink:NamedThing	betulin dehydrogenase activity	Catalysis of the reaction: betulin + NADPH(4-) + H+ + O2 <=> betulinic aldehyde + NADP(3-) + 2 H2O.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-13498									molecular_function											owl:Class	
GO:0007367	biolink:NamedThing	segment polarity determination	Division of the 14 parasegments of the embryo into anterior and posterior compartments; exemplified by the actions of the segment polarity gene products.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0050226	biolink:NamedThing	psychosine sulfotransferase activity	Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + galactosylsphingosine = adenosine 3',5'-bisphosphate + psychosine sulfate.	tmpzr1t_l9r_go_relaxed.owl	PAPS:psychosine sulphotransferase activity|3'-phosphoadenosine 5'-phosphosulfate-psychosine sulphotransferase activity|psychosine sulphotransferase activity|3'-phosphoadenylyl-sulfate:galactosylsphingosine sulfotransferase activity				EC:2.8.2.13|RHEA:14137|MetaCyc:PSYCHOSINE-SULFOTRANSFERASE-RXN									molecular_function											owl:Class	
GO:1902832	biolink:NamedThing	negative regulation of cell proliferation in dorsal spinal cord	Any process that stops, prevents or reduces the frequency, rate or extent of cell proliferation in dorsal spinal cord.	tmpzr1t_l9r_go_relaxed.owl	inhibition of cell proliferation in dorsal spinal cord|downregulation of cell proliferation in dorsal spinal cord|down-regulation of cell proliferation in dorsal spinal cord|down regulation of cell proliferation in dorsal spinal cord							mr	2014-03-31T17:42:50Z					biological_process											owl:Class	
GO:0072719	biolink:NamedThing	cellular response to cisplatin	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cisplatin stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2012-04-30T11:31:12Z					biological_process											owl:Class	
GO:0072718	biolink:NamedThing	response to cisplatin	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cisplatin stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2012-04-30T11:31:05Z					biological_process											owl:Class	
GO:0071300	biolink:NamedThing	cellular response to retinoic acid	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a retinoic acid stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to vitamin A acid							mah	2009-12-10T04:30:34Z					biological_process											owl:Class	
GO:0036160	biolink:NamedThing	melanocyte-stimulating hormone secretion	The regulated release of a melanocyte-stimulating hormone, any of a group of peptide hormones that are produced by cells in the intermediate lobe of the pituitary gland, and stimulate the production of melanin to increase pigmentation.	tmpzr1t_l9r_go_relaxed.owl	MSH secretion							bf	2012-03-26T01:16:55Z					biological_process											owl:Class	
GO:0008768	biolink:NamedThing	UDP-sugar diphosphatase activity	Catalysis of the reaction: UDP-sugar + H2O = UMP + sugar 1-phosphate.	tmpzr1t_l9r_go_relaxed.owl	nucleosidediphosphate-sugar pyrophosphatase activity|UDP-sugar pyrophosphatase activity|UDP-sugar hydrolase activity|UDP-sugar sugarphosphohydrolase activity|nucleosidediphosphate-sugar diphosphatase activity				MetaCyc:UDPSUGARHYDRO-RXN|Reactome:R-HSA-6810464|EC:3.6.1.45									molecular_function											owl:Class	
GO:0080051	biolink:NamedThing	cutin transport	The directed movement of cutin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Cutin, which consists of C16-18 fatty acids, is the major component of the cuticle that covers the plant surface.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0004482	biolink:NamedThing	mRNA (guanine-N7-)-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + G(5')pppR-RNA = S-adenosyl-L-homocysteine + m7G(5')pppR-RNA. m7G(5')pppR-RNA is mRNA containing an N7-methylguanine cap; R may be guanosine or adenosine.	tmpzr1t_l9r_go_relaxed.owl	guanine-7-methyltransferase activity|S-adenosyl-L-methionine:mRNA (guanine-7-N-)-methyltransferase activity|messenger ribonucleate guanine 7-methyltransferase activity|S-adenosyl-L-methionine:mRNA (guanine-N7-)-methyltransferase activity|messenger RNA guanine 7-methyltransferase activity				Reactome:R-HSA-9694476|EC:2.1.1.56|Reactome:R-HSA-9694492|Reactome:R-HSA-77090|MetaCyc:MRNA-GUANINE-N7--METHYLTRANSFERASE-RXN|Reactome:R-HSA-9684018|Reactome:R-HSA-9684017|Reactome:R-HSA-9694737|Reactome:R-HSA-9684016									molecular_function											owl:Class	
GO:0071265	biolink:NamedThing	L-methionine biosynthetic process	The chemical reactions and pathways resulting in the formation of L-methionine, the L-enantiomer of (2S)-2-amino-4-(methylsulfanyl)butanoic acid.	tmpzr1t_l9r_go_relaxed.owl	L-methionine biosynthesis|L-methionine anabolism|L-methionine synthesis|L-methionine formation							mah	2009-12-09T04:28:15Z					biological_process											owl:Class	
GO:0015792	biolink:NamedThing	arabinitol transmembrane transport	The process in which arabitol is transported across a lipid bilayer, from one side of a membrane to the other. Arabitol is the pentitol derived from arabinose or lyxose by reduction of the aldehyde group. The D enantiomer is present in lichens and mushrooms.	tmpzr1t_l9r_go_relaxed.owl	arabitol transport|arabinitol transport													biological_process											owl:Class	
GO:0031921	biolink:NamedThing	pyridoxal phosphate transport	The directed movement of pyridoxal phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore; pyridoxal phosphate is pyridoxal phosphorylated at the hydroxymethyl group of C-5, and is the active form of vitamin B6.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0048792	biolink:NamedThing	spontaneous exocytosis of neurotransmitter	The release of a neurotransmitter into the synaptic cleft, where the release step is independent of the presence of calcium ions (Ca2+). The neurotransmitter is contained within a membrane-bounded vesicle, and is released by fusion of the vesicle with the presynaptic plasma membrane of a nerve cell.	tmpzr1t_l9r_go_relaxed.owl	spontaneous synaptic vesicle exocytosis													biological_process											owl:Class	
GO:1904870	biolink:NamedThing	negative regulation of protein localization to Cajal body	Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to Cajal body.	tmpzr1t_l9r_go_relaxed.owl	down regulation of protein localization in Cajal body|downregulation of protein localization to Cajal body|negative regulation of protein localisation to Cajal body|down-regulation of protein localization to Cajal body|down-regulation of protein localisation to Cajal body|down-regulation of protein localisation in Cajal body|inhibition of protein localisation in Cajal body|negative regulation of protein localisation in Cajal body|downregulation of protein localisation in Cajal body|down regulation of protein localisation in Cajal body|inhibition of protein localization to Cajal body|down regulation of protein localization to Cajal body|down-regulation of protein localization in Cajal body|inhibition of protein localisation to Cajal body|down regulation of protein localisation to Cajal body|inhibition of protein localization in Cajal body|downregulation of protein localization in Cajal body|downregulation of protein localisation to Cajal body|negative regulation of protein localization in Cajal body							nc	2015-12-18T11:17:38Z					biological_process											owl:Class	
GO:0005920	biolink:NamedThing	smooth septate junction	A septate junction that lacks the regular arrays of electron-dense septae found in pleated septate junctions.	tmpzr1t_l9r_go_relaxed.owl	zonula continua													cellular_component											owl:Class	
GO:0005918	biolink:NamedThing	septate junction	A cell-cell junction that forms a continuous band around each cell in an epithelium; within the septate junction the membranes of adjacent cells maintain a constant distance of approximately 15 nm; found in arthropods.	tmpzr1t_l9r_go_relaxed.owl	septate desmosome				NIF_Subcellular:sao427941916									cellular_component											owl:Class	
GO:0000704	biolink:NamedThing	pyrimidine dimer DNA N-glycosylase activity	Catalysis of the removal of pyrimidine dimers by removing the 5' pyrimidine of the dimer by cleaving the N-C1' glycosidic bond between the 5' pyrimidine of the dimer and the deoxyribose sugar. The reaction releases the 5' pyrimidine of the dimer and leaves an apurinic (AP) site. The reaction involves the formation of a covalent enzyme substrate intermediate. Release of the enzyme and free base by a beta-elimination or a beta, gamma-elimination mechanism results in the cleavage of the DNA backbone 3' of the apyrimidinic (AP) site.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0048360	biolink:NamedThing	root cap mucilage metabolic process	The chemical reactions and pathways involving mucilage that occur in the root cap; mucilage is normally synthesized during root growth.	tmpzr1t_l9r_go_relaxed.owl	root cap mucilage metabolism													biological_process											owl:Class	
GO:0070483	biolink:NamedThing	detection of hypoxia	The series of events in which a stimulus indicating lowered oxygen tension is received by a cell and converted into a molecular signal. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level.	tmpzr1t_l9r_go_relaxed.owl	detection of reduced oxygen levels													biological_process											owl:Class	
GO:0008316	biolink:NamedThing	structural constituent of vitelline membrane	The action of a molecule that contributes to the structural integrity of the vitelline membrane of an egg. An example of this is found in Drosophila melanogaster.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0030302	biolink:NamedThing	deoxynucleotide transport	The directed movement of a deoxynucleotide, a deoxyribonucleoside in ester linkage to phosphate, commonly at the 5' position of deoxyribose, into, out of or within a cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0061995	biolink:NamedThing	ATP-dependent protein-DNA complex displacement activity	An activity that displaces proteins or protein complexes from DNA, sometimes in a 'wire stripping' fashion, driven by ATP hydrolysis.	tmpzr1t_l9r_go_relaxed.owl	ATP-dependent protein-nucleic acid complex displacement activity	https://github.com/geneontology/go-ontology/issues/21612						dph	2018-02-16T15:46:47Z			GO:0061994		molecular_function											owl:Class	
GO:0008737	biolink:NamedThing	L-fuculokinase activity	Catalysis of the reaction: L-fuculose + ATP = L-fuculose 1-phosphate + ADP + 2 H(+).	tmpzr1t_l9r_go_relaxed.owl	ATP:L-fuculose 1-phosphotransferase activity|L-fuculokinase (phosphorylating)|L-fuculose kinase activity				MetaCyc:FUCULOKIN-RXN|RHEA:12376|EC:2.7.1.51|KEGG_REACTION:R03241									molecular_function											owl:Class	
GO:0048174	biolink:NamedThing	negative regulation of short-term neuronal synaptic plasticity	A process that decreases short-term neuronal synaptic plasticity, the ability of neuronal synapses to change in the short-term as circumstances require. Short-term neuronal synaptic plasticity generally involves increasing or decreasing synaptic sensitivity.	tmpzr1t_l9r_go_relaxed.owl	down regulation of short-term neuronal synaptic plasticity|down-regulation of short-term neuronal synaptic plasticity|inhibition of short-term neuronal synaptic plasticity|downregulation of short-term neuronal synaptic plasticity					Note that the syntax of the definition of this term is different from the usual regulation syntax because it describes regulation of a trait rather than regulation of a process.								biological_process											owl:Class	
GO:1905378	biolink:NamedThing	cellular response to D-galactose	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a D-galactose stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to D-Gal|cellular response to D-galacto-hexose							sl	2016-08-17T22:17:32Z					biological_process											owl:Class	
GO:1901952	biolink:NamedThing	negative regulation of anterograde dense core granule transport	Any process that stops, prevents or reduces the frequency, rate or extent of anterograde dense core granule transport.	tmpzr1t_l9r_go_relaxed.owl	inhibition of anterograde dense core granule transport|downregulation of anterograde dense core granule transport|down-regulation of anterograde dense core granule transport|down regulation of anterograde dense core granule transport							pr	2013-02-19T13:36:30Z					biological_process											owl:Class	
GO:1901951	biolink:NamedThing	regulation of anterograde dense core granule transport	Any process that modulates the frequency, rate or extent of anterograde dense core granule transport.	tmpzr1t_l9r_go_relaxed.owl								pr	2013-02-19T13:36:21Z					biological_process											owl:Class	
GO:0050087	biolink:NamedThing	mannitol dehydrogenase (cytochrome) activity	Catalysis of the reaction: 2 [Fe(III)cytochrome c] + D-mannitol = 2 [Fe(II)cytochrome c] + D-fructose + 2 H+.	tmpzr1t_l9r_go_relaxed.owl	polyol dehydrogenase activity|D-mannitol:ferricytochrome-c 2-oxidoreductase activity				MetaCyc:MANNITOL-DEHYDROGENASE-CYTOCHROME-RXN|RHEA:17597|EC:1.1.2.2									molecular_function											owl:Class	
GO:0031972	biolink:NamedThing	chloroplast intermembrane space	The region between the inner and outer lipid bilayers of a chloroplast envelope.	tmpzr1t_l9r_go_relaxed.owl	chloroplast envelope lumen													cellular_component											owl:Class	
GO:1902789	biolink:NamedThing	cellular response to isooctane	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an isooctane stimulus.	tmpzr1t_l9r_go_relaxed.owl								tt	2014-03-21T20:52:58Z					biological_process											owl:Class	
GO:1902788	biolink:NamedThing	response to isooctane	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an isooctane stimulus.	tmpzr1t_l9r_go_relaxed.owl								tt	2014-03-21T20:52:51Z					biological_process											owl:Class	
GO:0002586	biolink:NamedThing	regulation of antigen processing and presentation of peptide antigen via MHC class II	Any process that modulates the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class II.	tmpzr1t_l9r_go_relaxed.owl	regulation of peptide antigen processing and presentation via MHC class II													biological_process											owl:Class	
GO:0003116	biolink:NamedThing	regulation of vasoconstriction by norepinephrine	Any process that modulates the frequency, rate or extent of reductions in the diameter of blood vessels as a result of secretion of norepinephrine into the bloodstream or released by nerve endings.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0018784	biolink:NamedThing	(S)-2-haloacid dehalogenase activity	Catalysis of the reaction: (S)-2-haloacid + H2O = (R)-2-hydroxyacid + halide.	tmpzr1t_l9r_go_relaxed.owl	2-haloacid dehalogenase activity|L-DEX activity|2-haloalkanoid acid halidohydrolase activity|halocarboxylic acid halidohydrolase activity|2-haloacid halidohydrolase activity|L-2-haloacid dehalogenase activity|DL-2-haloacid dehalogenase activity|2-halocarboxylic acid dehalogenase II activity|(S)-2-haloacid halidohydrolase activity|2-haloalkanoic acid dehalogenase activity				EC:3.8.1.2|MetaCyc:2-HALOACID-DEHALOGENASE-RXN|UM-BBD_reactionID:r0090|RHEA:11192									molecular_function											owl:Class	
GO:0036175	biolink:NamedThing	ribonucleoside-diphosphate reductase activity, glutaredoxin disulfide as acceptor	Catalysis of the reaction: 2'-deoxyribonucleoside diphosphate + glutaredoxin disulfide + H2O -> ribonucleoside diphosphate + glutaredoxin.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-8866405|Reactome:R-HSA-111742			bf	2012-03-29T11:12:42Z					molecular_function											owl:Class	
GO:1901975	biolink:NamedThing	glycerate transmembrane transport	The process in which glycerate is transported across a membrane.	tmpzr1t_l9r_go_relaxed.owl								ms	2013-03-05T16:48:50Z					biological_process											owl:Class	
GO:0070401	biolink:NamedThing	NADP+ binding	Binding to the oxidized form, NADP+, of nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions.	tmpzr1t_l9r_go_relaxed.owl	oxidized NADP binding|oxidized nicotinamide adenine dinucleotide phosphate binding|NADP (oxidized) binding|NADP binding													molecular_function											owl:Class	
GO:0006535	biolink:NamedThing	cysteine biosynthetic process from serine	The chemical reactions and pathways resulting in the formation of cysteine from other compounds, including serine.	tmpzr1t_l9r_go_relaxed.owl	cysteine synthesis from serine|cysteine anabolism from serine|cysteine formation from serine				MetaCyc:CYSTSYN-PWY									biological_process											owl:Class	
GO:0044567	biolink:NamedThing	primary cell wall cellulose synthase complex	A large, multimeric protein complex which catalyzes the biosynthesis of cellulose for the plant primary cell wall. In Arabidopsis, contains the essential component proteins CESA1 and -3, and a CESA6-related protein.	tmpzr1t_l9r_go_relaxed.owl	primary cell wall CESA complex|primary cell-wall cellulose synthase complex							jl	2012-04-18T12:24:16Z					cellular_component											owl:Class	
GO:0010330	biolink:NamedThing	cellulose synthase complex	A large, multimeric protein complex, organized in a rosette, which catalyzes the biosynthesis of cellulose for the plant cell wall.	tmpzr1t_l9r_go_relaxed.owl	CESA complex													cellular_component											owl:Class	
GO:0008488	biolink:NamedThing	gamma-glutamyl carboxylase activity	Catalysis of the reaction: peptidyl-glutamate + reduced vitamin K + CO2 + O2 = peptidyl-gamma-carboxyglutamate + vitamin K epoxide.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-159819|Reactome:R-HSA-159752|Reactome:R-HSA-9673231|Reactome:R-HSA-159761|Reactome:R-HSA-159826|Reactome:R-HSA-159803|Reactome:R-HSA-163810|EC:4.1.1.90|Reactome:R-HSA-6807214|RHEA:45140|Reactome:R-HSA-163820|Reactome:R-HSA-159795									molecular_function											owl:Class	
GO:0097354	biolink:NamedThing	prenylation	The covalent attachment of a prenyl group to a molecule; geranyl, farnesyl, or geranylgeranyl groups may be added.	tmpzr1t_l9r_go_relaxed.owl								pr	2012-07-03T01:12:19Z					biological_process											owl:Class	
GO:0016207	biolink:NamedThing	4-coumarate-CoA ligase activity	Catalysis of the reaction: ATP + 4-coumarate + CoA = AMP + diphosphate + 4-coumaroyl-CoA.	tmpzr1t_l9r_go_relaxed.owl	p-coumaryl-CoA synthetase activity|4-coumarate:coenzyme A ligase activity|4-coumarate-CoA synthetase activity|p-hydroxycinnamic acid:CoA ligase activity|4-coumaryl-CoA synthetase activity|4CL|p-hydroxycinnamoyl coenzyme A synthetase activity|sinapoyl coenzyme A synthetase activity|4-coumaroyl-CoA synthetase activity|p-coumaryl-CoA ligase activity|hydroxycinnamoyl CoA synthetase activity|feruloyl CoA ligase activity|feruloyl coenzyme A synthetase activity|4-coumarate:CoA ligase activity|4-coumaroyl-CoA synthase activity|caffeolyl coenzyme A synthetase activity|p-coumaryl coenzyme A synthetase activity|4-coumarate:CoA ligase (AMP-forming)|hydroxycinnamate:CoA ligase activity|p-coumaroyl CoA ligase activity				KEGG_REACTION:R01616|RHEA:19641|EC:6.2.1.12|MetaCyc:4-COUMARATE--COA-LIGASE-RXN									molecular_function											owl:Class	
GO:0102890	biolink:NamedThing	naringenin chalcone 4'-O-glucosyltransferase activity	Catalysis of the reaction: UDP-alpha-D-glucose + 2',4,4',6'-tetrahydroxychalcone <=> UDP + 2',4,4',6'-tetrahydroxychalcone 4'-O-beta-D-glucoside + H+.	tmpzr1t_l9r_go_relaxed.owl					EC:2.4.1.286|MetaCyc:RXN-8453|RHEA:34291									molecular_function											owl:Class	
GO:0008953	biolink:NamedThing	penicillin amidase activity	Catalysis of the reaction: penicillin + H2O = a carboxylate + 6-aminopenicillanate.	tmpzr1t_l9r_go_relaxed.owl	palmitoleoyl [acyl-carrier protein]-dependent acyltransferase activity|benzylpenicillin acylase activity|semacylase activity|penicillin acylase activity|penicillin amidohydrolase activity|alpha-acylamino-beta-lactam acylhydrolase activity|novozym 217|ampicillin acylase activity				RHEA:18693|MetaCyc:PENICILLIN-AMIDASE-RXN|EC:3.5.1.11									molecular_function											owl:Class	
GO:1901006	biolink:NamedThing	ubiquinone-6 biosynthetic process	The chemical reactions and pathways resulting in the formation of ubiquinone-6.	tmpzr1t_l9r_go_relaxed.owl	ubiquinone-6 formation|ubiquinone-6 anabolism|ubiquinone-6 synthesis|ubiquinone-6 biosynthesis							bf	2012-06-15T09:59:58Z					biological_process											owl:Class	
GO:0044354	biolink:NamedThing	macropinosome	A membrane-bounded, uncoated intracellular vesicle formed by the process of macropinocytosis.	tmpzr1t_l9r_go_relaxed.owl								jl	2011-08-11T10:51:42Z					cellular_component											owl:Class	
GO:0038131	biolink:NamedThing	neuregulin receptor activity	Combining with a neuregulin, a member of the EGF family of growth factors, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	NRG receptor activity|NRG1 receptor activity|NRG2 receptor activity					Consider also annotating to 'ERBB3 signaling pathway ; GO:0038129' and/or 'ERBB4 signaling pathway ; GO:0038130'.		bf	2012-03-30T10:47:11Z					molecular_function											owl:Class	
GO:1901450	biolink:NamedThing	positive regulation of response to butan-1-ol	Any process that activates or increases the frequency, rate or extent of response to butan-1-ol.	tmpzr1t_l9r_go_relaxed.owl	upregulation of response to butan-1-ol|up-regulation of response to butan-1-ol|up regulation of response to butan-1-ol|activation of response to butan-1-ol							tt	2012-10-02T14:17:17Z					biological_process											owl:Class	
GO:0001550	biolink:NamedThing	ovarian cumulus expansion	Increase in size of the cumulus surrounding the oocyte including change in morphology due to proliferation and dispersion of cumulus cells.	tmpzr1t_l9r_go_relaxed.owl	ovarian cumulus growth													biological_process											owl:Class	
GO:0042272	biolink:NamedThing	nuclear RNA export factor complex	A protein complex that contains two proteins (know in several organisms, including Drosophila, as NXF1 and NXF2) and is required for the export of the majority of mRNAs from the nucleus to the cytoplasm; localized in the nucleoplasm and at both the nucleoplasmic and cytoplasmic faces of the nuclear pore complex; shuttles between the nucleus and the cytoplasm.	tmpzr1t_l9r_go_relaxed.owl	TAP-p15 complex|NXF1-NXT1 complex|Mex67-Mtr2 complex													cellular_component											owl:Class	
GO:0010997	biolink:NamedThing	anaphase-promoting complex binding	Binding to an anaphase-promoting complex. A ubiquitin ligase complex that degrades mitotic cyclins and anaphase inhibitory protein, thereby triggering sister chromatid separation and exit from mitosis.	tmpzr1t_l9r_go_relaxed.owl	APC binding							tb	2009-06-10T11:18:22Z					molecular_function											owl:Class	
GO:0098709	biolink:NamedThing	glutathione import across plasma membrane	The directed movement of glutathione from outside of a cell, across the plasma membrane and into the cytosol.	tmpzr1t_l9r_go_relaxed.owl	glutathione uptake|glutathione import into cell							bf	2012-09-18T14:29:19Z			GO:0036347		biological_process											owl:Class	
GO:0000762	biolink:NamedThing	pheromone-induced unidirectional conjugation	The process of unidirectional (polarized) transfer of genetic information in response to a pheromone. It involves direct cellular contact between a donor and recipient cell; the contact is followed by the formation of a cellular bridge that physically connects the cells; some or all of the chromosome(s) of one cell ('male') is then transferred into the other cell ('female'); unidirectional conjugation occurs between cells of different mating types.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0072016	biolink:NamedThing	glomerular parietal epithelial cell development	The process whose specific outcome is the progression of a glomerular parietal epithelial cell over time, from its formation to the mature structure. Glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport.	tmpzr1t_l9r_go_relaxed.owl	Bowman's capsule development							mah	2010-01-25T02:13:16Z					biological_process											owl:Class	
GO:0001048	biolink:NamedThing	RNA polymerase IV core binding	Binding to RNA polymerase IV core enzyme, a multisubunit eukaryotic nuclear RNA polymerase found in plants and involved in siRNA production.	tmpzr1t_l9r_go_relaxed.owl								krc	2010-09-23T01:41:03Z					molecular_function											owl:Class	
GO:0039668	biolink:NamedThing	viral entry into host cell via pilus basal pore	The uptake of a virus or viral genetic material into a host cell which occurs through retraction of the virion-bound pilus, followed by entry of the viral genome into the host cell through the pilus basal pore. Filamentous bacteriophages absorb to the tip of the F-pili and can enter the bacterial cell in this way.	tmpzr1t_l9r_go_relaxed.owl	filamentous viral entry into host cell via pilus retraction							bf	2013-09-04T14:33:18Z					biological_process											owl:Class	
GO:0004799	biolink:NamedThing	thymidylate synthase activity	Catalysis of the reaction: 5,10-methylenetetrahydrofolate + dUMP = 7,8-dihydrofolate + thymidylate.	tmpzr1t_l9r_go_relaxed.owl	TMP synthetase activity|5,10-methylenetetrahydrofolate:dUMP C-methyltransferase activity|dTMP synthase activity|methylenetetrahydrofolate:dUMP C-methyltransferase activity|thymidylate synthetase activity				EC:2.1.1.45|MetaCyc:THYMIDYLATESYN-RXN|Reactome:R-HSA-73605|RHEA:12104|KEGG_REACTION:R02101									molecular_function											owl:Class	
GO:0052829	biolink:NamedThing	inositol-1,3,4-trisphosphate 1-phosphatase activity	Catalysis of the reaction: D-myo-inositol 1,3,4-trisphosphate + H2O = myo-inositol 3,4-bisphosphate + phosphate.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-1855232			ai	2011-11-29T09:58:00Z					molecular_function											owl:Class	
GO:0046081	biolink:NamedThing	dUTP catabolic process	The chemical reactions and pathways resulting in the breakdown of dUTP, deoxyuridine (5'-)triphosphate.	tmpzr1t_l9r_go_relaxed.owl	dUTP breakdown|dUTP degradation|dUTP catabolism													biological_process											owl:Class	
GO:0042543	biolink:NamedThing	protein N-linked glycosylation via arginine	The glycosylation of protein via peptidyl-arginine, omega-N-glycosyl-L-arginine.	tmpzr1t_l9r_go_relaxed.owl	protein amino acid N-linked glycosylation via arginine				RESID:AA0327									biological_process											owl:Class	
GO:0047525	biolink:NamedThing	2'-hydroxydaidzein reductase activity	Catalysis of the reaction: 2'-hydroxydihydrodaidzein + NADP+ = 2'-hydroxydaidzein + NADPH + H+.	tmpzr1t_l9r_go_relaxed.owl	HDR activity|2'-hydroxydihydrodaidzein:NADP(+) 2'-oxidoreductase activity|NADPH:2'-hydroxydaidzein oxidoreductase activity|2'-hydroxydihydrodaidzein:NADP+ 2'-oxidoreductase activity|2'-hydroxy-2,3-dihydrodaidzein:NADP+ 2'-oxidoreductase activity				RHEA:17145|EC:1.3.1.51|MetaCyc:RXN-4502									molecular_function											owl:Class	
GO:1990655	biolink:NamedThing	4 iron, 3 sulfur cluster binding	Binding to a 4 iron, 3 sulfur (4Fe-3S) cluster, an uncommon iron-sulfur cluster with unique properties found in oxygen-tolerant Ni-Fe hydrogenases of various bacteria.	tmpzr1t_l9r_go_relaxed.owl	4Fe-3S cluster binding							pr	2015-02-24T17:07:23Z					molecular_function											owl:Class	
GO:0060288	biolink:NamedThing	formation of a compartment boundary	Formation of a lineage restriction boundary within a developing tissue which does not correspond to some morphological barrier.	tmpzr1t_l9r_go_relaxed.owl	compartment boundary formation													biological_process											owl:Class	
GO:1904348	biolink:NamedThing	negative regulation of small intestine smooth muscle contraction	Any process that stops, prevents or reduces the frequency, rate or extent of small intestine smooth muscle contraction.	tmpzr1t_l9r_go_relaxed.owl	inhibition of small intestine smooth muscle contraction|downregulation of small intestine smooth muscle contraction|down regulation of small intestine smooth muscle contraction|down-regulation of small intestine smooth muscle contraction							sl	2015-06-11T21:37:40Z					biological_process											owl:Class	
GO:0036244	biolink:NamedThing	cellular response to neutral pH	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a neutral pH (pH close to 7) stimulus. pH is a measure of the acidity or basicity of an aqueous solution.	tmpzr1t_l9r_go_relaxed.owl								bf	2012-05-28T10:21:03Z					biological_process											owl:Class	
GO:0102887	biolink:NamedThing	beta-sesquiphellandrene synthase activity	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate <=> beta-sesquiphellandrene + diphosphoric acid.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-8430|EC:4.2.3.123|RHEA:32699									molecular_function											owl:Class	
GO:0140526	biolink:NamedThing	double membrane vesicle viral factory assembly	A process that results in the assembly of a cytoplasmic viral factory consisting of a double-membrane bound vesicle.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/19943						pg	2020-09-29T08:26:51Z					biological_process											owl:Class	
GO:0016155	biolink:NamedThing	formyltetrahydrofolate dehydrogenase activity	Catalysis of the reaction: 10-formyltetrahydrofolate + H(2)O + NADP(+) = (6S)-5,6,7,8-tetrahydrofolate + CO(2) + H(+) + NADPH.	tmpzr1t_l9r_go_relaxed.owl	10-formyltetrahydrofolate:NADP+ oxidoreductase activity|10-formyl-H2PtGlu:NADP oxidoreductase activity|10-formyltetrahydrofolate dehydrogenase activity|N10-formyltetrahydrofolate dehydrogenase activity|10-formyl tetrahydrofolate:NADP oxidoreductase activity|10-formyl-H4folate dehydrogenase activity				MetaCyc:FORMYLTETRAHYDROFOLATE-DEHYDROGENASE-RXN|EC:1.5.1.6|RHEA:10180|KEGG_REACTION:R00941									molecular_function											owl:Class	
GO:0004190	biolink:NamedThing	aspartic-type endopeptidase activity	Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which a water molecule bound by the side chains of aspartic residues at the active center acts as a nucleophile.	tmpzr1t_l9r_go_relaxed.owl	carboxyl protease activity|aspartate protease activity|aspartic protease activity|aspartic endopeptidase activity|aspartyl protease activity				Reactome:R-HSA-2022403|Reactome:R-HSA-157640|Reactome:R-HSA-2220988|Reactome:R-HSA-2065357|Reactome:R-HSA-9013361|Reactome:R-HSA-9604294|Reactome:R-HSA-2022412|Reactome:R-HSA-9017817|Reactome:R-HSA-157353|EC:3.4.23.-|Reactome:R-HSA-373705									molecular_function											owl:Class	
GO:0002236	biolink:NamedThing	detection of misfolded protein	The series of events in which a misfolded protein stimulus is received and converted into a molecular signal.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0055075	biolink:NamedThing	potassium ion homeostasis	Any process involved in the maintenance of an internal steady state of potassium ions within an organism or cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0018464	biolink:NamedThing	3-hydroxypimeloyl-CoA dehydrogenase activity	Catalysis of the reaction: 3-hydroxypimelyl-CoA + NAD(+) = 3-oxopimelyl-CoA + H(+) + NADH.	tmpzr1t_l9r_go_relaxed.owl	3-hydroxypimeloyl-CoA:NAD+ oxidoreductase activity				MetaCyc:1.1.1.259-RXN|KEGG_REACTION:R05305|UM-BBD_reactionID:r0196|RHEA:11168|EC:1.1.1.259									molecular_function											owl:Class	
GO:1904758	biolink:NamedThing	protein localization to new growing cell tip	A process in which a protein is transported to, or maintained in, a location within a new growing cell tip.	tmpzr1t_l9r_go_relaxed.owl	protein localization in new growing cell tip|protein localisation in new growing cell tip|protein localization to post-new end take-off new cell tip|protein localisation to new growing cell tip|protein localization to new growing cell end|protein localization to new cell tip after activation of bipolar cell growth|protein localization to post-NETO new cell tip|protein localization to post-NETO new cell end							mah	2015-10-21T12:37:48Z					biological_process											owl:Class	
GO:0042959	biolink:NamedThing	alkanesulfonate transmembrane transporter activity	Enables the directed movement of alkanesulfonate from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	alkanesulphonate transporter activity|alkanesulfonate transporter activity													molecular_function											owl:Class	
GO:0090486	biolink:NamedThing	small RNA 2'-O-methyltransferase	Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to the oxygen atom of a nucleoside residue in a small RNA molecule. Reaction: S-adenosyl-L-methionine + small RNA <=> S-adenosyl-L-homocysteine + small RNA containing a 3'-terminal 2'-O-methylnucleotide.	tmpzr1t_l9r_go_relaxed.owl								tb	2012-10-15T16:32:49Z					molecular_function											owl:Class	
GO:2001149	biolink:NamedThing	negative regulation of dipeptide transmembrane transport	Any process that stops, prevents or reduces the frequency, rate or extent of dipeptide transmembrane transport.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of dipeptide membrane transport							kmv	2011-10-21T06:09:59Z					biological_process											owl:Class	
GO:0072476	biolink:NamedThing	response to mitotic spindle checkpoint signaling	A process that occurs in response to signals generated as a result of mitotic cell cycle spindle checkpoint signaling.	tmpzr1t_l9r_go_relaxed.owl	response to mitotic cell cycle spindle checkpoint signaling|response to signal involved in mitotic cell cycle spindle checkpoint|mitotic cell cycle spindle checkpoint effector process							mah	2010-12-09T11:50:09Z					biological_process											owl:Class	
GO:0072417	biolink:NamedThing	response to spindle checkpoint signaling	A process that occurs in response to signals generated as a result of spindle checkpoint signaling.	tmpzr1t_l9r_go_relaxed.owl	spindle checkpoint effector process|response to signal involved in spindle checkpoint							mah	2010-12-08T03:56:04Z					biological_process											owl:Class	
GO:0031622	biolink:NamedThing	positive regulation of fever generation	Any process that activates or increases the frequency, rate, or extent of fever generation.	tmpzr1t_l9r_go_relaxed.owl	activation of fever|upregulation of fever|up-regulation of fever|stimulation of fever|up regulation of fever|positive regulation of pyrexia													biological_process											owl:Class	
GO:0061177	biolink:NamedThing	type Is terminal bouton	Terminal inflated portion of the axon of a glutamatergic neuron, containing the specialized apparatus necessary for the phasic release neurotransmitters that will induce the contraction of muscle. Type Is terminal boutons are smaller than type Ib terminal boutons.	tmpzr1t_l9r_go_relaxed.owl	type Is terminal button							dph	2010-07-13T09:25:15Z					cellular_component											owl:Class	
GO:1902950	biolink:NamedThing	regulation of dendritic spine maintenance	Any process that modulates the frequency, rate or extent of dendritic spine maintenance.	tmpzr1t_l9r_go_relaxed.owl								sjp	2014-05-02T08:48:47Z					biological_process											owl:Class	
GO:0090455	biolink:NamedThing	ornithine transmembrane import into vacuole	The directed movement of ornithine into the vacuole across the vacuolar membrane.	tmpzr1t_l9r_go_relaxed.owl	vacuolar ornithine import							tb	2012-09-24T14:12:46Z					biological_process											owl:Class	
GO:2001159	biolink:NamedThing	regulation of protein localization by the Cvt pathway	Any process that modulates the frequency, rate or extent of protein localization by the Cvt pathway.	tmpzr1t_l9r_go_relaxed.owl	regulation of cytoplasm-to-vacuole targeting|regulation of cytoplasm to vacuole targeting							jp	2011-10-25T10:22:24Z					biological_process											owl:Class	
GO:0005121	biolink:NamedThing	Toll binding	Binding to a Toll protein, a transmembrane receptor.	tmpzr1t_l9r_go_relaxed.owl	Toll ligand|Tl binding|Toll receptor binding													molecular_function											owl:Class	
GO:0039593	biolink:NamedThing	suppression by virus of host exit from mitosis	Any viral process which decreases the rate or extent of a host cell leaving M phase of the cell cycle. M phase is the part of the mitotic cell cycle during which mitosis and cytokinesis take place.	tmpzr1t_l9r_go_relaxed.owl	inhibition of host mitotic exit by virus				VZ:877			bf	2012-06-25T02:21:20Z					biological_process											owl:Class	
GO:0000823	biolink:NamedThing	inositol-1,4,5-trisphosphate 6-kinase activity	Catalysis of the reaction: D-myo-inositol 1,4,5-trisphosphate + ATP = D-myo-inositol 1,4,5,6-tetrakisphosphate + ADP + 2 H(+).	tmpzr1t_l9r_go_relaxed.owl	inositol polyphosphate multikinase activity|IpmK|ATP:1D-myo-inositol-1,4,5-trisphosphate 6-phosphotransferase activity|inositol trisphosphate 6-kinase activity				MetaCyc:2.7.1.151-RXN|KEGG_REACTION:R05800|EC:2.7.1.151									molecular_function											owl:Class	
GO:0051766	biolink:NamedThing	inositol trisphosphate kinase activity	Catalysis of the reaction: inositol trisphosphate + ATP = inositol tetrakisphosphate + ADP.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1902040	biolink:NamedThing	positive regulation of seed dormancy process	Any process that activates or increases the frequency, rate or extent of seed dormancy process.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of seed dormancy|activation of seed dormancy process|up-regulation of seed dormancy process|positive regulation of seed dormancy|upregulation of seed dormancy process|activation of seed dormancy|up regulation of seed dormancy process|up regulation of seed dormancy|upregulation of seed dormancy							tb	2013-04-02T22:13:20Z					biological_process											owl:Class	
GO:1902517	biolink:NamedThing	glycerol-3-phosphate-transporting ATPase complex	A protein complex which is capable of glycerol-3-phosphate-transporting ATPase activity.	tmpzr1t_l9r_go_relaxed.owl						An example of this is UgpB in E. coli in PMID:23013274.		bhm	2013-11-27T16:53:33Z					cellular_component											owl:Class	
GO:0051753	biolink:NamedThing	mannan synthase activity	Catalysis of the reaction: mannan(n) + GDP-mannose = mannan(n+1) + GDP. This reaction is the formation of the beta-(1->4)-linked mannan backbone in substrates such as galactomannan.	tmpzr1t_l9r_go_relaxed.owl	mannan beta-1,4-mannosyltransferase activity|galactomannan beta-1,4-mannosyltransferase activity													molecular_function											owl:Class	
GO:0070965	biolink:NamedThing	positive regulation of neutrophil mediated killing of fungus	Any process that increases the frequency, rate or extent of the directed killing of a fungal cell by a neutrophil.	tmpzr1t_l9r_go_relaxed.owl	upregulation of neutrophil mediated killing of fungus|up-regulation of neutrophil mediated killing of fungus|up regulation of neutrophil mediated killing of fungus|activation of neutrophil mediated killing of fungus|stimulation of neutrophil mediated killing of fungus							mah	2009-10-01T02:28:49Z					biological_process											owl:Class	
GO:1900667	biolink:NamedThing	regulation of endocrocin biosynthetic process	Any process that modulates the frequency, rate or extent of endocrocin biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of endocrocin biosynthesis|regulation of endocrocin anabolism|regulation of endocrocin formation|regulation of endocrocin synthesis							di	2012-05-22T04:16:04Z					biological_process											owl:Class	
GO:0102137	biolink:NamedThing	7-oxateasterone synthase activity	Catalysis of the reaction: H+ + teasterone + NADPH + O2 <=> 7-oxateasterone + NADP + H2O.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-11537									molecular_function											owl:Class	
GO:0016688	biolink:NamedThing	L-ascorbate peroxidase activity	Catalysis of the reaction: L-ascorbate + hydrogen peroxide = dehydroascorbate + 2 H2O.	tmpzr1t_l9r_go_relaxed.owl	L-ascorbic acid peroxidase activity|L-ascorbate:hydrogen-peroxide oxidoreductase activity|L-ascorbic acid-specific peroxidase activity|ascorbic acid peroxidase activity|ascorbate peroxidase activity				EC:1.11.1.11|MetaCyc:L-ASCORBATE-PEROXIDASE-RXN|RHEA:22996									molecular_function											owl:Class	
GO:0031584	biolink:NamedThing	activation of phospholipase D activity	Any process that initiates the activity of inactive phospholipase D.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0043506	biolink:NamedThing	regulation of JUN kinase activity	Any process that modulates the frequency, rate or extent of JUN kinase activity.	tmpzr1t_l9r_go_relaxed.owl	regulation of JUNK activity													biological_process											owl:Class	
GO:1904314	biolink:NamedThing	cellular response to methamphetamine hydrochloride	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methamphetamine hydrochloride stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to methamphetamine HCL							sl	2015-06-10T17:47:15Z					biological_process											owl:Class	
GO:0045459	biolink:NamedThing	iron incorporation into iron-sulfur cluster via tetrakis-L-cysteinyl triiron tetrasulfide	The incorporation of iron into a 3Fe-4S iron-sulfur cluster via tetrakis-L-cysteinyl triiron tetrasulfide.	tmpzr1t_l9r_go_relaxed.owl	iron incorporation into iron-sulphur cluster via tetrakis-L-cysteinyl triiron tetrasulphide				RESID:AA0326									biological_process											owl:Class	
GO:0051462	biolink:NamedThing	regulation of cortisol secretion	Any process that modulates the frequency, rate or extent of the regulated release of cortisol from a cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0016180	biolink:NamedThing	snRNA processing	Any process involved in the conversion of a primary small nuclear RNA (snRNA) transcript into a mature snRNA molecule.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0090396	biolink:NamedThing	leaf papilla	A plant cell papilla that is part of a leaf papilla cell.	tmpzr1t_l9r_go_relaxed.owl						Part of leaf papilla cell (PO:0025167).		tb	2010-12-15T03:26:20Z					cellular_component											owl:Class	
GO:0044668	biolink:NamedThing	sodium:malonate symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sodium(out)+ malonate(out) = sodium(in) + malonate(in).	tmpzr1t_l9r_go_relaxed.owl					RHEA:33135			jl	2012-08-08T11:59:48Z					molecular_function											owl:Class	
GO:0042663	biolink:NamedThing	regulation of endodermal cell fate specification	Any process that mediates the specification of a cell into an endoderm cell.	tmpzr1t_l9r_go_relaxed.owl	regulation of endoderm cell fate specification													biological_process											owl:Class	
GO:0062181	biolink:NamedThing	1-alpha,25-dihydroxyvitamin D3 23-hydroxylase activity	Catatlysis of the reaction: calcitriol + 2 H(+) + O2 + 2 reduced [adrenodoxin] = 1alpha,23S,25-trihydroxycholecalciferol + H2O + 2 oxidized [adrenodoxin].	tmpzr1t_l9r_go_relaxed.owl					RHEA:49192			dph	2019-11-26T17:16:39Z					molecular_function											owl:Class	
GO:0062179	biolink:NamedThing	vitamin D 23-hydroxylase activity	Catalysis of the hydroxylation of C-23 of any form of vitamin D.	tmpzr1t_l9r_go_relaxed.owl								dph	2019-11-26T17:10:29Z					molecular_function											owl:Class	
GO:0042377	biolink:NamedThing	vitamin K catabolic process	The chemical reactions and pathways resulting in the breakdown of any of the forms of vitamin K, quinone-derived vitamins which are involved in the synthesis of blood-clotting factors in mammals.	tmpzr1t_l9r_go_relaxed.owl	vitamin K breakdown|naphthoquinone catabolic process|naphthoquinone catabolism|vitamin K catabolism|vitamin K degradation													biological_process											owl:Class	
GO:0047682	biolink:NamedThing	aryl-alcohol oxidase activity	Catalysis of the reaction: an aromatic primary alcohol + O2 = an aromatic aldehyde + H2O2.	tmpzr1t_l9r_go_relaxed.owl	aryl alcohol oxidase activity|arom. alcohol oxidase activity|aryl-alcohol:oxygen oxidoreductase activity|veratryl alcohol oxidase activity				MetaCyc:ARYL-ALCOHOL-OXIDASE-RXN|RHEA:17541|EC:1.1.3.7									molecular_function											owl:Class	
GO:1904985	biolink:NamedThing	negative regulation of quinolinate biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of quinolinate biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of quinolinate formation|downregulation of quinolinate synthesis|downregulation of quinolinate anabolism|down regulation of quinolinate biosynthetic process|inhibition of quinolinate biosynthetic process|negative regulation of quinolinate formation|downregulation of quinolinate biosynthesis|inhibition of quinolinate formation|inhibition of quinolinate anabolism|down regulation of quinolinate formation|down regulation of quinolinate synthesis|down regulation of quinolinate anabolism|negative regulation of quinolinate anabolism|down-regulation of quinolinate biosynthetic process|down-regulation of quinolinate anabolism|negative regulation of quinolinate biosynthesis|negative regulation of quinolinate synthesis|down regulation of quinolinate biosynthesis|down-regulation of quinolinate biosynthesis|down-regulation of quinolinate synthesis|inhibition of quinolinate synthesis|inhibition of quinolinate biosynthesis|downregulation of quinolinate biosynthetic process|downregulation of quinolinate formation							bf	2016-02-29T15:54:21Z					biological_process											owl:Class	
GO:0071374	biolink:NamedThing	cellular response to parathyroid hormone stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a parathyroid hormone stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-12-11T03:19:29Z					biological_process											owl:Class	
GO:0044388	biolink:NamedThing	small protein activating enzyme binding	Binding to a small protein activating enzyme, such as ubiquitin-activating enzyme.	tmpzr1t_l9r_go_relaxed.owl								jl	2011-12-15T04:28:17Z					molecular_function											owl:Class	
GO:0032988	biolink:NamedThing	ribonucleoprotein complex disassembly	The disaggregation of a protein-RNA complex into its constituent components.	tmpzr1t_l9r_go_relaxed.owl	RNP complex disassembly|RNA-protein complex disassembly|protein-RNA complex disassembly													biological_process											owl:Class	
GO:0003110	biolink:NamedThing	positive regulation of the force of heart contraction by neuronal norepinephrine	The process in which the release of norepinephrine from nerve endings modulates the force of heart muscle contraction.	tmpzr1t_l9r_go_relaxed.owl	increased force of heart contraction by neuronal norepinephrine|increased force of heart contraction by neuronal noradrenaline													biological_process											owl:Class	
GO:1903926	biolink:NamedThing	cellular response to bisphenol A	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bisphenol A stimulus.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-02-11T00:17:04Z					biological_process											owl:Class	
GO:1903925	biolink:NamedThing	response to bisphenol A	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bisphenol A stimulus.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-02-11T00:16:46Z					biological_process											owl:Class	
GO:0102658	biolink:NamedThing	2-oxo-5-methylthiopentanoate aminotransferase activity	Catalysis of the reaction: 5-methylthio-2-oxopentanoate + a standard alpha amino acid <=> L-homomethionine + a 2-oxo carboxylate.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-2205									molecular_function											owl:Class	
GO:0019375	biolink:NamedThing	galactolipid biosynthetic process	The chemical reactions and pathways resulting in the formation of galactolipids, any glycolipid containing one of more residues of galactose and/or N-acetylgalactosamine.	tmpzr1t_l9r_go_relaxed.owl	galactolipid anabolism|galactolipid biosynthesis|galactolipid synthesis|galactolipid formation													biological_process											owl:Class	
GO:0097488	biolink:NamedThing	multivesicular body, internal vesicle membrane	The lipid bilayer surrounding a multivesicular body internal vesicle.	tmpzr1t_l9r_go_relaxed.owl								pr	2013-07-08T20:36:33Z					cellular_component											owl:Class	
GO:0018687	biolink:NamedThing	biphenyl 2,3-dioxygenase activity	Catalysis of the reaction: biphenyl + NADH + H+ + O2 = (2R,3S)-3-phenylcyclohexa-3,5-diene-1,2-diol + NAD+. This reaction requires Fe2+.	tmpzr1t_l9r_go_relaxed.owl	biphenyl dioxygenase activity|biphenyl,NADH:oxygen oxidoreductase (2,3-hydroxylating)				RHEA:18165|EC:1.14.12.18|UM-BBD_enzymeID:e0089|MetaCyc:1.14.12.18-RXN									molecular_function											owl:Class	
GO:0032220	biolink:NamedThing	plasma membrane fusion involved in cytogamy	The joining of two or more lipid bilayer membranes that surround cells, that contributes to cytogamy.	tmpzr1t_l9r_go_relaxed.owl	plasma membrane fusion during cytogamy|plasma membrane organization involved in conjugation with cellular fusion	https://github.com/geneontology/go-ontology/issues/16258						mah	2009-08-20T02:24:56Z			GO:0070872		biological_process											owl:Class	
GO:0036429	biolink:NamedThing	adenosylcobinamide kinase (ATP-specific) activity	Catalysis of the reaction: adenosylcobinamide + ATP = adenosylcobinamide phosphate + ADP + H+.	tmpzr1t_l9r_go_relaxed.owl					RHEA:15769|KEGG_REACTION:R05221|MetaCyc:COBINAMIDEKIN-RXN			bf	2013-09-16T14:05:56Z					molecular_function											owl:Class	
GO:0043752	biolink:NamedThing	adenosylcobinamide kinase activity	Catalysis of the reaction: RTP + adenosylcobinamide = adenosylcobinamide phosphate + RDP (where RTP is either ATP or GTP).	tmpzr1t_l9r_go_relaxed.owl	adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase|RTP:adenosylcobinamide phosphotransferase activity|CobU|AdoCbi kinase/AdoCbi-phosphate guanylyltransferase				MetaCyc:2.7.1.156-RXN|EC:2.7.1.156									molecular_function											owl:Class	
GO:0034153	biolink:NamedThing	positive regulation of toll-like receptor 6 signaling pathway	Any process that activates or increases the frequency, rate, or extent of toll-like receptor 6 signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of toll-like receptor 6 signalling pathway|positive regulation of TLR6 signaling pathway													biological_process											owl:Class	
GO:1905905	biolink:NamedThing	pharyngeal gland morphogenesis	The developmental process by which a pharyngeal gland is generated and organized.	tmpzr1t_l9r_go_relaxed.owl	pharynx gland morphogenesis|glandulae pharyngeae morphogenesis							rz	2017-02-03T14:39:10Z					biological_process											owl:Class	
GO:0008879	biolink:NamedThing	glucose-1-phosphate thymidylyltransferase activity	Catalysis of the reaction: alpha-D-glucose 1-phosphate + dTTP = diphosphate + dTDP-glucose.	tmpzr1t_l9r_go_relaxed.owl	dTDP-glucose pyrophosphorylase activity|TDP-glucose pyrophosphorylase activity|thymidine diphosphoglucose pyrophosphorylase activity|dTDP-glucose diphosphorylase activity|dTDP-glucose synthase activity|dTTP:alpha-D-glucose-1-phosphate thymidylyltransferase activity|glucose 1-phosphate thymidylyltransferase activity|thymidine diphosphate glucose pyrophosphorylase activity				EC:2.7.7.24|RHEA:15225|KEGG_REACTION:R02328|MetaCyc:DTDPGLUCOSEPP-RXN									molecular_function											owl:Class	
GO:0035704	biolink:NamedThing	helper T cell chemotaxis	The directed movement of a helper T cell in response to an external stimulus.	tmpzr1t_l9r_go_relaxed.owl	T-helper cell chemotaxis							bf	2011-03-02T02:31:48Z					biological_process											owl:Class	
GO:2001106	biolink:NamedThing	regulation of Rho guanyl-nucleotide exchange factor activity	Any process that modulates the frequency, rate or extent of Rho guanyl-nucleotide exchange factor activity.	tmpzr1t_l9r_go_relaxed.owl	regulation of RhoGEF|regulation of Rho guanine nucleotide exchange factor							yaf	2011-09-23T10:13:06Z					biological_process											owl:Class	
GO:0061480	biolink:NamedThing	response to asparaginase	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an asparaginase stimulus.	tmpzr1t_l9r_go_relaxed.owl								dph	2012-11-07T09:13:08Z					biological_process											owl:Class	
GO:0045249	biolink:NamedThing	cytosol pyruvate dehydrogenase (lipoamide) phosphatase complex	A cytosolic complex of a regulatory and catalytic subunit that catalyzes the dephosphorylation and concomitant reactivation of the alpha subunit of the E1 component of the pyruvate dehydrogenase complex.	tmpzr1t_l9r_go_relaxed.owl						See also the cellular component term 'cytosolic pyruvate dehydrogenase complex ; GO:0045250'.								cellular_component											owl:Class	
GO:0061672	biolink:NamedThing	glutathione hydrolase complex	Enzyme complex that in S. cerevisiae has components Dug2/Dug3 and is able to catalyze the cleavage of glutathione into glutamate and Cys-Gly.	tmpzr1t_l9r_go_relaxed.owl	glutamine amidotransferase II complex|gamma-glutamyltranspeptidase complex|glutathionase complex							dph	2014-11-24T14:38:08Z					cellular_component											owl:Class	
GO:0050580	biolink:NamedThing	2,5-didehydrogluconate reductase activity	Catalysis of the reaction: 2-dehydro-D-gluconate + NADP+ = 2,5-didehydro-D-gluconate + NADPH + H+.	tmpzr1t_l9r_go_relaxed.owl	2,5-diketo-D-gluconate reductase activity|2-dehydro-D-gluconate:NADP+ 2-oxidoreductase activity|YqhE reductase				RHEA:23828|MetaCyc:1.1.1.274-RXN|EC:1.1.1.274									molecular_function											owl:Class	
GO:0032485	biolink:NamedThing	regulation of Ral protein signal transduction	Any process that modulates the frequency, rate or extent of Ral protein signal transduction.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0150090	biolink:NamedThing	multiple spine synapse organization, single dendrite	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a synapse between a multiple synapse bouton and a single dendrite.	tmpzr1t_l9r_go_relaxed.owl								bc	2018-08-08T14:59:49Z					biological_process											owl:Class	
GO:0150089	biolink:NamedThing	multiple spine synapse organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a synapse between a multiple synapse bouton and one or more dendritic spines.	tmpzr1t_l9r_go_relaxed.owl	multisynapse organization|multiple spine synapse organisation|multisynapse organisation|multisynaptic organization|multi-synaptic organisation|multi-synapse organization|multisynaptic organisation|multi-synaptic organization|multi-synapse organisation							bc	2018-08-08T14:54:50Z					biological_process											owl:Class	
GO:0140141	biolink:NamedThing	mitochondrial potassium ion transmembrane transport	The process in which a potassium ion is transported across a mitochondrial membrane, into or out of the mitochondrion.	tmpzr1t_l9r_go_relaxed.owl								pg	2017-11-24T13:26:42Z					biological_process											owl:Class	
GO:0071942	biolink:NamedThing	XPC complex	A nucleotide-excision repair complex that is involved in damage sensing during global genome nucleotide excision repair (GG-NER). It is part of the pre-incision (or initial recognition) complex bound to sites of DNA damage. In human, it is composed of XPC, RAD23B and CETN2.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-10-01T11:09:36Z					cellular_component											owl:Class	
GO:0098853	biolink:NamedThing	endoplasmic reticulum-vacuole membrane contact site	A zone of apposition between endoplasmic-reticulum and lytic vacuole membranes, structured by bridging complexes.	tmpzr1t_l9r_go_relaxed.owl	ER-vacuole membrane contact site													cellular_component											owl:Class	
GO:0003991	biolink:NamedThing	acetylglutamate kinase activity	Catalysis of the reaction: ATP + N-acetyl-L-glutamate = ADP + N-acetyl-L-glutamate-5-phosphate.	tmpzr1t_l9r_go_relaxed.owl	N-acetylglutamate kinase activity|N-acetylglutamic 5-phosphotransferase activity|ATP:N-acetyl-L-glutamate 5-phosphotransferase activity|acetylglutamate phosphokinase activity|N-acetylglutamate 5-phosphotransferase activity|N-acetylglutamate phosphokinase activity				MetaCyc:ACETYLGLUTKIN-RXN|EC:2.7.2.8|RHEA:14629									molecular_function											owl:Class	
GO:0045152	biolink:NamedThing	antisigma factor binding	Binding to an antisigma factor, a factor which inhibits the ability of the sigma factor to function as a transcriptional initiator.	tmpzr1t_l9r_go_relaxed.owl	antisigma factor antagonist activity													molecular_function											owl:Class	
GO:0050411	biolink:NamedThing	agaritine gamma-glutamyltransferase activity	Catalysis of the reaction: agaritine + acceptor-NH2 = 4-hydroxymethylphenylhydrazine + gamma-L-glutamyl-acceptor.	tmpzr1t_l9r_go_relaxed.owl	(gamma-L-glutamyl)-N1-(4-hydroxymethylphenyl)hydrazine:(acceptor) gamma-glutamyltransferase activity|(gamma-L-glutamyl)-1-N-(4-hydroxymethylphenyl)hydrazine:(acceptor) gamma-glutamyltransferase activity|agaritine g-glutamyltransferase activity				MetaCyc:AGARITINE-GAMMA-GLUTAMYLTRANSFERASE-RXN|EC:2.3.2.9									molecular_function											owl:Class	
GO:0002861	biolink:NamedThing	regulation of inflammatory response to antigenic stimulus	Any process that modulates the frequency, rate, or extent of an inflammatory response to an antigenic stimulus.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0071260	biolink:NamedThing	cellular response to mechanical stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mechanical stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular mechanical stimulus response							mah	2009-12-04T03:55:44Z					biological_process											owl:Class	
GO:0019013	biolink:NamedThing	viral nucleocapsid	The complete protein-nucleic acid complex that is the packaged form of the genome in a virus particle.	tmpzr1t_l9r_go_relaxed.owl	nucleocapsid|core											GO:0019014		cellular_component											owl:Class	
GO:0043909	biolink:NamedThing	N-acetylcitrulline deacetylase activity	Catalysis of the reaction: N-acetyl-L-citrulline + H2O = citrulline + acetate.	tmpzr1t_l9r_go_relaxed.owl	N-acetyl-L-citrulline deacetylase activity|acetylcitrulline deacetylase activity				RHEA:61092									molecular_function											owl:Class	
GO:0033812	biolink:NamedThing	3-oxoadipyl-CoA thiolase activity	Catalysis of the reaction: succinyl-CoA + acetyl-CoA = CoA + 3-oxoadipyl-CoA.	tmpzr1t_l9r_go_relaxed.owl	succinyl-CoA:acetyl-CoA C-succinyltransferase activity				MetaCyc:RXN-3641|EC:2.3.1.174|RHEA:19481									molecular_function											owl:Class	
GO:1900996	biolink:NamedThing	benzene catabolic process	The chemical reactions and pathways resulting in the breakdown of benzene.	tmpzr1t_l9r_go_relaxed.owl	benzene degradation|benzene catabolism|benzene breakdown							yaf	2012-06-14T02:53:38Z					biological_process											owl:Class	
GO:0004358	biolink:NamedThing	glutamate N-acetyltransferase activity	Catalysis of the reaction: N(2)-acetyl-L-ornithine + L-glutamate = N-acetyl-L-glutamate + L-ornithine.	tmpzr1t_l9r_go_relaxed.owl	N-acetylglutamate synthase activity|acetylglutamic-acetylornithine transacetylase activity|acetylornithine glutamate acetyltransferase activity|N2-acetyl-L-ornithine:L-glutamate N-acetyltransferase activity|alpha-N-acetyl-L-ornithine:L-glutamate N-acetyltransferase activity|acetylornithinase activity|2-N-acetyl-L-ornithine:L-glutamate N-acetyltransferase activity|ornithine transacetylase activity|ornithine acetyltransferase activity|N-acetylglutamate synthetase activity|acetylglutamate synthetase activity|acetylglutamic synthetase activity|acetylglutamate-acetylornithine transacetylase activity|N-acetyl-L-glutamate synthetase activity|glutamate acetyltransferase activity				KEGG_REACTION:R02282|RHEA:15349|EC:2.3.1.35|MetaCyc:GLUTAMATE-N-ACETYLTRANSFERASE-RXN									molecular_function											owl:Class	
GO:0033740	biolink:NamedThing	hydroxylamine oxidoreductase activity	Catalysis of the reactions: hydroxylamine + NH3 = hydrazine + H2O, and hydrazine + acceptor = N2 + reduced acceptor.	tmpzr1t_l9r_go_relaxed.owl	hydroxylamine:acceptor oxidoreductase activity				RHEA:23232|EC:1.7.2.8|MetaCyc:1.7.99.8-RXN									molecular_function											owl:Class	
GO:0090617	biolink:NamedThing	mitochondrial mRNA 5'-end processing	Any process involved in forming the mature 5' end of an mRNA molecule that derives from the mitochondrial genome.	tmpzr1t_l9r_go_relaxed.owl								tb	2014-10-24T12:45:08Z					biological_process											owl:Class	
GO:1990190	biolink:NamedThing	peptide-glutamate-N-acetyltransferase activity	Catalysis of the reaction: acetyl-CoA + N-terminal L-glutamate in peptide = CoA + N-acetyl-L-glutamate-peptide.	tmpzr1t_l9r_go_relaxed.owl								tb	2013-09-11T20:21:25Z					molecular_function											owl:Class	
GO:0052496	biolink:NamedThing	occlusion by host of symbiont xylem	The process in which an organism reduces the flow of fluid within the symbiont xylem, the tissue in plants that carries water and nutrients up from the roots to the shoot and leaves. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0052494	biolink:NamedThing	occlusion by host of symbiont vascular system	The process in which an organism reduces the flow of fluid within its symbiont's vascular system, the vessels and tissue that carry or circulate fluids, such as blood, lymph or sap, through the body of an animal or plant. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0097498	biolink:NamedThing	endothelial tube lumen extension	Any endothelial tube morphogenesis process by which the tube is increased in length.	tmpzr1t_l9r_go_relaxed.owl								pr	2013-08-12T13:49:54Z					biological_process											owl:Class	
GO:0018166	biolink:NamedThing	C-terminal protein-tyrosinylation	The ATP-dependent addition of a tyrosine residue to the C-terminus of a protein; typically the addition of tyrosine to the C-terminus of detyrosinated alpha-tubulin by the enzyme tubulin-tyrosine ligase.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0257	See also the molecular function term 'tubulin-tyrosine ligase activity ; GO:0004835'.								biological_process											owl:Class	
GO:0051120	biolink:NamedThing	hepoxilin A3 synthase activity	Catalysis of the reaction: 12S-5Z,8Z,10E,14Z-12-hydro(pero)xy-eicosa-5,8,10,14-tetraenoic acid = (5Z,9E,14Z)-(8,11R,12S)-11,12-epoxy-8-hydroxyicosa-5,9,14-trienoate. 12S-5Z,8Z,10E,14Z-12-hydro(pero)xy-eicosa-5,8,10,14-tetraenoic acid is also known as 12S-HpETE, and (5Z,9E,14Z)-(8,11R,12S)-11,12-epoxy-8-hydroxyicosa-5,9,14-trienoate as hepoxilin A3.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-8942208|Reactome:R-HSA-2161794									molecular_function											owl:Class	
GO:0103002	biolink:NamedThing	16-hydroxypalmitate dehydrogenase activity	Catalysis of the reaction: 16-hydroxypalmitate + NADP <=> H+ + 16-oxo-palmitate + NADPH.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-9802									molecular_function											owl:Class	
GO:0043638	biolink:NamedThing	puromycin biosynthetic process	The chemical reactions and pathways resulting in the formation of puromycin, an aminonucleoside antibiotic that is a potent inhibitor of translation; produced by the bacterium Streptomyces alboniger.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0061011	biolink:NamedThing	hepatic duct development	The progression of the hepatic duct over time, from its formation to the mature structure. The hepatic duct is the duct that leads from the liver to the common bile duct.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-01-22T09:44:39Z					biological_process											owl:Class	
GO:0061009	biolink:NamedThing	common bile duct development	The progression of the common bile duct over time, from its formation to the mature structure. The common bile duct is formed from the joining of the common hepatic duct running from the liver, and the cystic duct running from the gall bladder. The common bile duct transports bile from the liver and gall bladder to the intestine.	tmpzr1t_l9r_go_relaxed.owl	bile duct development|CBD development|EHBD development|extrahepatic bile duct development							dph	2010-01-22T09:17:13Z					biological_process											owl:Class	
GO:0010099	biolink:NamedThing	regulation of photomorphogenesis	Any process that modulates the rate or extent of photomorphogenesis.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0036227	biolink:NamedThing	mitotic G2 cell cycle arrest in response to glucose starvation	The process in which the mitotic cell cycle is halted during G2 phase as a result of deprivation of glucose.	tmpzr1t_l9r_go_relaxed.owl								bf	2012-05-09T02:45:49Z					biological_process											owl:Class	
GO:0004014	biolink:NamedThing	adenosylmethionine decarboxylase activity	Catalysis of the reaction: S-adenosyl-L-methionine + H(+) = S-adenosylmethioninamine + CO(2).	tmpzr1t_l9r_go_relaxed.owl	S-adenosyl-L-methionine carboxy-lyase [(5-deoxy-5-adenosyl)(3-aminopropyl)-methylsulfonium-salt-forming]|S-adenosyl-L-methionine decarboxylase activity|S-adenosyl-L-methionine carboxy-lyase activity|S-adenosylmethionine decarboxylase activity|adenosyl methionine decarboxylase activity				RHEA:15981|Reactome:R-HSA-351222|MetaCyc:SAMDECARB-RXN|EC:4.1.1.50|KEGG_REACTION:R00178									molecular_function											owl:Class	
GO:1902804	biolink:NamedThing	negative regulation of synaptic vesicle transport	Any process that stops, prevents or reduces the frequency, rate or extent of synaptic vesicle transport.	tmpzr1t_l9r_go_relaxed.owl	down regulation of synaptic vesicle transport|down-regulation of synaptic vesicle fusion|downregulation of synaptic vesicle transport|down-regulation of synaptic vesicle transport|down regulation of synaptic vesicle fission|down-regulation of synaptic vesicle fission|down regulation of synaptic vesicle fusion|negative regulation of synaptic vesicle fission|negative regulation of synaptic vesicle fusion|downregulation of synaptic vesicle fusion|inhibition of synaptic vesicle transport|downregulation of synaptic vesicle fission|inhibition of synaptic vesicle fission|inhibition of synaptic vesicle fusion							kmv	2014-03-25T14:56:40Z					biological_process											owl:Class	
GO:0140596	biolink:NamedThing	TOM complex	A large mitochondrial outer membrane translocase complex that mediates transport of proteins into mitochondrial compartments. TOM transports beta-barrel precursors across the outer membrane and the sorting and assembly machinery (SAM complex) inserts them into the target membrane.	tmpzr1t_l9r_go_relaxed.owl	translocase of the outer mitochondrial membrane	https://github.com/geneontology/go-ontology/issues/20669						pg	2021-02-09T19:43:51Z					cellular_component											owl:Class	
GO:0005742	biolink:NamedThing	mitochondrial outer membrane translocase complex	A large complex of the mitochondrial outer membrane that mediates transport of proteins into all mitochondrial compartments.	tmpzr1t_l9r_go_relaxed.owl	GIP complex|mitochondrion outer membrane translocase complex													cellular_component											owl:Class	
GO:0006588	biolink:NamedThing	activation of tryptophan 5-monooxygenase activity	The process in which the tryptophan 5-monooxygenase enzyme is changed so that it can carry out its enzymatic activity.	tmpzr1t_l9r_go_relaxed.owl	tryptophan hydroxylase activation													biological_process											owl:Class	
GO:0008310	biolink:NamedThing	single-stranded DNA 3'-5' exodeoxyribonuclease activity	Catalysis of the sequential cleavage of mononucleotides from a free 3' terminus of a single-stranded DNA molecule.	tmpzr1t_l9r_go_relaxed.owl	single-stranded DNA specific 3'-5' exodeoxyribonuclease activity|ssDNA-specific 3'-5' exodeoxyribonuclease activity													molecular_function											owl:Class	
GO:0008296	biolink:NamedThing	3'-5'-exodeoxyribonuclease activity	Catalysis of the sequential cleavage of mononucleotides from a free 3' terminus of a DNA molecule.	tmpzr1t_l9r_go_relaxed.owl	3'-5' exodeoxyribonuclease activity				Reactome:R-HSA-9023943									molecular_function											owl:Class	
GO:0098733	biolink:NamedThing	hemidesmosome associated protein complex	Any protein complex that is part of or has some part in a hemidesmosome.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0102597	biolink:NamedThing	3alpha-hydroxy-ent-sandaracopimardiene 9-beta-monooxygenase activity	Catalysis of the reaction: ent-sandaracopimaradien-3-beta-ol + NADPH + H+ + O2 <=> oryzalexin E + NADP + H2O.	tmpzr1t_l9r_go_relaxed.owl					RHEA:41468|EC:1.14.14.122|MetaCyc:RXN-15381									molecular_function											owl:Class	
GO:0061238	biolink:NamedThing	establishment of planar polarity involved in mesonephric nephron morphogenesis	Coordinated organization of groups of cells in the plane of an epithelium that contributes to the shaping of a nephron in the mesonephros.	tmpzr1t_l9r_go_relaxed.owl	establishment of planar cell polarity involved in mesonephric nephron morphogenesis							dph	2010-08-19T03:04:40Z					biological_process											owl:Class	
GO:0050584	biolink:NamedThing	linoleate 11-lipoxygenase activity	Catalysis of the reaction: linoleate + O(2) = (9Z,11S,12Z)-11-hydroperoxyoctadeca-9,12-dienoate.	tmpzr1t_l9r_go_relaxed.owl	manganese lipoxygenase activity|linoleate:oxygen 11S-oxidoreductase activity|linoleate dioxygenase activity				KEGG_REACTION:R05718|EC:1.13.11.45|RHEA:18993|MetaCyc:1.13.11.45-RXN									molecular_function											owl:Class	
GO:2001080	biolink:NamedThing	chitosan binding	Binding to chitosan.	tmpzr1t_l9r_go_relaxed.owl								jl	2011-09-15T01:17:32Z					molecular_function											owl:Class	
GO:0016905	biolink:NamedThing	myosin heavy chain kinase activity	Catalysis of the reaction: ATP + myosin-heavy-chain = ADP + myosin-heavy-chain phosphate.	tmpzr1t_l9r_go_relaxed.owl	calmodulin-dependent myosin heavy chain kinase activity|myosin heavy-chain kinase activity|myosin-heavy-chain kinase activity|myosin heavy chain kinase A activity|STK6|ATP:myosin-heavy-chain O-phosphotransferase activity|myosin II heavy-chain kinase activity|MIHC kinase activity|ATP:myosin heavy-chain O-phosphotransferase activity|myosin I heavy-chain kinase activity|MHCK|myosin I heavy chain kinase activity|myosin II heavy chain kinase activity				EC:2.7.11.7|RHEA:11424									molecular_function											owl:Class	
GO:0006702	biolink:NamedThing	androgen biosynthetic process	The chemical reactions and pathways resulting in the formation of androgens, C19 steroid hormones that can stimulate the development of male sexual characteristics.	tmpzr1t_l9r_go_relaxed.owl	androgen formation|androgen biosynthesis|androgen synthesis|androgen anabolism													biological_process											owl:Class	
GO:0031144	biolink:NamedThing	proteasome localization	Any process in which the proteasome is transported to, or maintained in, a specific location.	tmpzr1t_l9r_go_relaxed.owl	establishment and maintenance of proteasome localization|proteasome localisation													biological_process											owl:Class	
GO:0018626	biolink:NamedThing	2-chlorobenzoate 1,2-dioxygenase activity	Catalysis of the reaction: 2-chlorobenzoate + NADH + H+ + O2 = catechol + chloride + NAD+ + CO2.	tmpzr1t_l9r_go_relaxed.owl	2-chlorobenzoate,NADH:oxygen oxidoreductase (1,2-hydroxylating, dechlorinating, decarboxylating)|2-halobenzoate 1,2-dioxygenase activity				MetaCyc:2-CHLOROBENZOATE-12-DIOXYGENASE-RXN|EC:1.14.12.13|RHEA:21652|UM-BBD_reactionID:r0632									molecular_function											owl:Class	
GO:0047729	biolink:NamedThing	carnitine decarboxylase activity	Catalysis of the reaction: carnitine + H(+) = 2-methylcholine + CO(2).	tmpzr1t_l9r_go_relaxed.owl	carnitine carboxy-lyase (2-methylcholine-forming)|carnitine carboxy-lyase activity				KEGG_REACTION:R02398|EC:4.1.1.42|RHEA:21576|MetaCyc:CARNITINE-DECARBOXYLASE-RXN									molecular_function											owl:Class	
GO:0052895	biolink:NamedThing	N1-acetylspermine:oxygen oxidoreductase (N1-acetylspermidine-forming) activity	Catalysis of the reaction: N1-acetylspermine + oxygen + H2O = N1-acetylspermidine + 3-aminopropanal + hydrogen peroxide.	tmpzr1t_l9r_go_relaxed.owl	N1-acetylspermine oxidase activity				MetaCyc:POLYAMINE-OXIDASE-RXN|EC:1.5.3.16									molecular_function											owl:Class	
GO:1904172	biolink:NamedThing	positive regulation of bleb assembly	Any process that activates or increases the frequency, rate or extent of bleb assembly.	tmpzr1t_l9r_go_relaxed.owl	activation of cell blebbing|up-regulation of cell blebbing|activation of bleb assembly|upregulation of cell blebbing|positive regulation of cell blebbing|upregulation of bleb assembly|up-regulation of bleb assembly|up regulation of cell blebbing|up regulation of bleb assembly							als	2015-04-23T09:32:31Z					biological_process											owl:Class	
GO:1901593	biolink:NamedThing	response to GW 7647	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a GW 7647 stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2012-11-07T17:16:48Z					biological_process											owl:Class	
GO:1905705	biolink:NamedThing	cellular response to paclitaxel	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a paclitaxel stimulus.	tmpzr1t_l9r_go_relaxed.owl								sl	2016-11-16T21:40:32Z					biological_process											owl:Class	
GO:1901555	biolink:NamedThing	response to paclitaxel	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a paclitaxel stimulus.	tmpzr1t_l9r_go_relaxed.owl								hp	2012-11-02T09:46:08Z					biological_process											owl:Class	
GO:0042797	biolink:NamedThing	tRNA transcription by RNA polymerase III	The synthesis of transfer RNA (tRNA) from a DNA template by RNA polymerase III (Pol III), originating at a Pol III promoter.	tmpzr1t_l9r_go_relaxed.owl	tRNA transcription from Pol III promoter|tRNA transcription from RNA polymerase III promoter	https://github.com/geneontology/go-ontology/issues/14854												biological_process											owl:Class	
GO:0140627	biolink:NamedThing	ubiquitin-dependent protein catabolic process via the C-end degron rule pathway	The chemical reactions and pathways resulting in the breakdown of a protein or peptide covalently tagged with ubiquitin, via the DesCEND (destruction via C-end degron) pathway. In the DesCEND pathway, C-terminal residues (C-end degrons) in substrates are recognized by Cul2-RING and Cul4-RING E3 ligases, whereupon the substrates are linked to ubiquitin and then delivered to the proteasome for degradation. C-end degrons can be present in full-length proteins, truncated proteins or proteolytically cleaved forms.	tmpzr1t_l9r_go_relaxed.owl	DesCEND	https://github.com/geneontology/go-ontology/issues/21184						pg	2021-03-24T07:30:47Z					biological_process											owl:Class	
GO:0032773	biolink:NamedThing	positive regulation of tyrosinase activity	Any process that activates or increases the activity of a tyrosinase enzyme monophenol oxygenase.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of monophenol monooxygenase activity|activation of monophenol oxygenase activity|positive regulation of monophenol oxygenase activity|up-regulation of monophenol oxygenase activity|up regulation of monophenol oxygenase activity|upregulation of monophenol oxygenase activity|stimulation of monophenol oxygenase activity	https://github.com/geneontology/go-ontology/issues/21024												biological_process											owl:Class	
GO:0070054	biolink:NamedThing	mRNA splicing, via endonucleolytic cleavage and ligation	Splicing of mRNA substrates via recognition of the folded RNA structure that brings the 5' and 3' splice sites into proximity and cleavage of the RNA at both the 3' and 5' splice sites by an endonucleolytic mechanism, followed by ligation of the exons.	tmpzr1t_l9r_go_relaxed.owl	cytosolic mRNA splicing					Note that while typically associated with tRNA splicing, splicing via endonucleolytic cleavages and subsequent ligation of the free exon ends is known to be used for some non-tRNA substrates, e.g. HAC1 (YFL031W) in S. cerevisiae and an intron in the 23S rRNA of the Archaeal species Desulfurococcus mobilis.						GO:0061012		biological_process											owl:Class	
GO:0007232	biolink:NamedThing	osmosensory signaling pathway via Sho1 osmosensor	A series of molecular signals generated in response to osmotic change, as mediated through a Sho1 osmosensor system.	tmpzr1t_l9r_go_relaxed.owl	signal transduction during osmotic stress via Sho1 osmosensor|osmosensory signalling pathway via Sho1 osmosensor													biological_process											owl:Class	
GO:0007231	biolink:NamedThing	osmosensory signaling pathway	The series of molecular signals initiated in response to osmotic change.	tmpzr1t_l9r_go_relaxed.owl	osmosensory signalling pathway|osmolarity sensing signalling pathway|osmolarity sensing|signal transduction during osmotic stress|osmosensory signal transduction|osmolarity sensing signaling pathway	https://github.com/geneontology/go-ontology/issues/20368												biological_process											owl:Class	
GO:0042902	biolink:NamedThing	peptidoglycan-protein cross-linking via L-threonyl-pentaglycyl-murein	The process of linking a protein to peptidoglycan via a carboxy terminal threonine carboxyl group through a pentaglycyl peptide to the lysine or diaminopimelic acid of the peptidoglycan.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0345									biological_process											owl:Class	
GO:0047725	biolink:NamedThing	inulosucrase activity	Catalysis of the reaction: sucrose + 2,1-beta-D-fructosyl(n) = glucose + 2,1-beta-D-fructosyl(n+1).	tmpzr1t_l9r_go_relaxed.owl	sucrose 1-fructosyl transferase activity|sucrose 1-fructosyltransferase activity|sucrose:2,1-beta-D-fructan 1-beta-D-fructosyltransferase activity				RHEA:15745|EC:2.4.1.9|MetaCyc:INULOSUCRASE-RXN									molecular_function											owl:Class	
GO:0007376	biolink:NamedThing	cephalic furrow formation	Formation of a partial necklace of inturning tissue on the lateral sides of the embryo, along the dorsal-ventral axis. This furrow demarcates head from thorax in the developing protostome.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1902192	biolink:NamedThing	2-methylbut-2-enoyl-CoA(4-) metabolic process	The chemical reactions and pathways involving 2-methylbut-2-enoyl-CoA(4-).	tmpzr1t_l9r_go_relaxed.owl	2-methylbut-2-enoyl-CoA(4-) metabolism							ms	2013-06-06T09:40:30Z					biological_process											owl:Class	
GO:0047428	biolink:NamedThing	arylacetonitrilase activity	Catalysis of the reaction: 2 H2O + 4-chlorophenylacetonitrile = 4-chlorophenylacetate + NH3.	tmpzr1t_l9r_go_relaxed.owl	arylacetonitrile aminohydrolase activity				RHEA:20657|EC:3.5.5.5|MetaCyc:3.5.5.5-RXN									molecular_function											owl:Class	
GO:0005168	biolink:NamedThing	neurotrophin TRKA receptor binding	Binding to a neurotrophin TRKA receptor.	tmpzr1t_l9r_go_relaxed.owl	neurotrophin TRKA receptor ligand													molecular_function											owl:Class	
GO:1902111	biolink:NamedThing	response to diethyl maleate	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diethyl maleate stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2013-05-08T16:00:35Z					biological_process											owl:Class	
GO:0097228	biolink:NamedThing	sperm principal piece	The segment of the sperm flagellum where the mitochondrial sheath ends, and the outer dense fibers (ODFs) associated with outer axonemal doublets 3 and 8 are replaced by the 2 longitudinal columns of the fibrous sheath (FS) which run the length of the principal piece and are stabilized by circumferential ribs. The principal piece makes up ~2/3 of the length of the sperm flagellum and is defined by the presence of the FS and of only 7 (rather than 9) ODFs which taper and then terminate near the distal end of the principal piece.	tmpzr1t_l9r_go_relaxed.owl								pr	2012-01-25T01:27:27Z					cellular_component											owl:Class	
GO:0033961	biolink:NamedThing	cis-stilbene-oxide hydrolase activity	Catalysis of the reaction: cis-stilbene oxide + H2O = (+)-(1R,2R)-1,2-diphenylethane-1,2-diol.	tmpzr1t_l9r_go_relaxed.owl	benzo[a]pyrene-4,5-oxide hydratase activity|microsomal epoxide hydratase activity|epoxide hydrase activity|mEH|aryl epoxide hydrase activity|microsomal epoxide hydrase activity|cis-epoxide hydrolase activity|benzo(a)pyrene-4,5-epoxide hydratase activity|epoxide hydratase activity|microsomal epoxide hydrolase activity|arene-oxide hydratase activity				RHEA:23900|EC:3.3.2.9|MetaCyc:3.3.2.9-RXN|Reactome:R-HSA-5694077									molecular_function											owl:Class	
GO:0009338	biolink:NamedThing	exodeoxyribonuclease V complex	An enzyme complex that catalyzes exonucleolytic cleavage (in the presence of ATP) in either 5' to 3' or 3' to 5' direction to yield 5'-phosphooligonucleotides. Exodeoxyribonuclease V shows a preference for double-stranded DNA and possesses DNA-dependent ATPase activity. It acts endonucleolytically on single-stranded circular DNA.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0016844	biolink:NamedThing	strictosidine synthase activity	Catalysis of the reaction: 3alpha(S)-strictosidine + H(2)O = secologanin + tryptamine.	tmpzr1t_l9r_go_relaxed.owl	STR activity|3-alpha(S)-strictosidine tryptamine-lyase activity|3-alpha(S)-strictosidine tryptamine-lyase (secologanin-forming)|strictosidine synthetase activity				KEGG_REACTION:R03738|EC:4.3.3.2|RHEA:15013|MetaCyc:STRICTOSIDINE-SYNTHASE-RXN									molecular_function											owl:Class	
GO:0031799	biolink:NamedThing	type 2 metabotropic glutamate receptor binding	Binding to a type 2 metabotropic glutamate receptor.	tmpzr1t_l9r_go_relaxed.owl	type 2 metabotropic glutamate receptor ligand													molecular_function											owl:Class	
GO:0090113	biolink:NamedThing	regulation of ER to Golgi vesicle-mediated transport by GTP hydrolysis	The GTP hydrolysis process that modulates the rate, frequency, or extent of ER to Golgi vesicle-mediated transport, the directed movement of substances from the endoplasmic reticulum (ER) to the Golgi, mediated by COP II vesicles.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-12-06T09:16:14Z					biological_process											owl:Class	
GO:0097750	biolink:NamedThing	endosome membrane tubulation	A membrane tubulation process occurring in an endosome membrane.	tmpzr1t_l9r_go_relaxed.owl	endosomal membrane tubulation							pr	2016-12-21T12:33:09Z					biological_process											owl:Class	
GO:0018979	biolink:NamedThing	trichloroethylene metabolic process	The chemical reactions and pathways involving trichloroethylene, a toxic, colorless, photoreactive, chlorinated hydrocarbon liquid, commonly used as a metal degreaser and solvent.	tmpzr1t_l9r_go_relaxed.owl	trichloroethene metabolism|TCE metabolism|trichloroethylene metabolism|trichloroethene metabolic process|TCE metabolic process				UM-BBD_pathwayID:tce									biological_process											owl:Class	
GO:1904983	biolink:NamedThing	glycine import into mitochondrion	The process in which glycine is transported from the cytosol into the mitochondrial matrix.	tmpzr1t_l9r_go_relaxed.owl	transmembrane glycine transport from cytosol to mitochondrion							vw	2016-02-28T21:53:44Z					biological_process											owl:Class	
GO:0033097	biolink:NamedThing	amyloplast membrane	Either of the lipid bilayers that surround an amyloplast and form the amyloplast envelope.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0032807	biolink:NamedThing	DNA ligase IV complex	A eukaryotically conserved protein complex that contains DNA ligase IV and is involved in DNA repair by non-homologous end joining; in addition to the ligase, the complex also contains XRCC4 or a homolog, e.g. Saccharomyces Lif1p.	tmpzr1t_l9r_go_relaxed.owl	DNA ligase IV-XRCC4 complex													cellular_component											owl:Class	
GO:0010949	biolink:NamedThing	negative regulation of intestinal phytosterol absorption	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of phytosterols into the blood by absorption from the small intestine.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-04-27T11:02:06Z					biological_process											owl:Class	
GO:0061872	biolink:NamedThing	hepatic stellate cell contraction	The actin filament-based process in which cytoplasmic actin filaments slide past one another resulting in contraction of a hepatic stellate cell.	tmpzr1t_l9r_go_relaxed.owl								dph	2017-05-01T13:25:18Z					biological_process											owl:Class	
GO:0009146	biolink:NamedThing	purine nucleoside triphosphate catabolic process	The chemical reactions and pathways resulting in the breakdown of purine nucleoside triphosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with triphosphate on the sugar.	tmpzr1t_l9r_go_relaxed.owl	purine nucleoside triphosphate catabolism|purine nucleoside triphosphate degradation|purine nucleoside triphosphate breakdown													biological_process											owl:Class	
GO:0031483	biolink:NamedThing	myosin XIII complex	A myosin complex containing one or more class XIII myosin heavy chains and associated light chains.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0009554	biolink:NamedThing	megasporogenesis	The process in which the megasporocyte undergoes meiosis, giving rise to four haploid megaspores in the nucellus.	tmpzr1t_l9r_go_relaxed.owl	megaspore mother cell meiosis|megaspore development|meiosis of the megasporocyte|meiotic division of the megasporocyte													biological_process											owl:Class	
GO:0086062	biolink:NamedThing	voltage-gated sodium channel activity involved in Purkinje myocyte action potential	Enables the transmembrane transfer of a sodium ion by a voltage-gated channel through the plasma membrane of a Purkinje myocyte contributing to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.	tmpzr1t_l9r_go_relaxed.owl								dph	2011-11-17T01:50:43Z					molecular_function											owl:Class	
GO:0018739	biolink:NamedThing	4-hydroxybenzoyl-CoA thioesterase activity	Catalysis of the reaction: 4-hydroxybenzoyl-CoA + H(2)O = 4-hydroxybenzoate + CoA + H(+).	tmpzr1t_l9r_go_relaxed.owl	4-hydroxybenzoyl-CoA hydrolase activity|4-hydroxybenzoyl-CoA thiolesterase activity				MetaCyc:3.1.2.23-RXN|UM-BBD_reactionID:r0141|KEGG_REACTION:R01301|RHEA:11948|EC:3.1.2.23									molecular_function											owl:Class	
GO:0004808	biolink:NamedThing	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + tRNA containing 5-aminomethyl-2-thiouridine = S-adenosyl-L-homocysteine + tRNA containing 5-methylaminomethyl-2-thiouridylate.	tmpzr1t_l9r_go_relaxed.owl	tRNA 5-methylaminomethyl-2-thiouridylate 5'-methyltransferase activity|S-adenosyl-L-methionine:tRNA (5-methylaminomethyl-2-thio-uridylate)-methyltransferase activity|transfer ribonucleate 5-methylaminomethyl-2-thiouridylate 5-methyltransferase activity				MetaCyc:2.1.1.61-RXN|RHEA:19569|EC:2.1.1.61|KEGG_REACTION:R00601							GO:0016425		molecular_function											owl:Class	
GO:1901795	biolink:NamedThing	3-(3-hydroxyphenyl)propanoate biosynthetic process	The chemical reactions and pathways resulting in the formation of 3-(3-hydroxyphenyl)propanoate.	tmpzr1t_l9r_go_relaxed.owl	3-(3-hydroxyphenyl)propanoate synthesis|3-(3-hydroxyphenyl)propanoate anabolism|3-(3-hydroxyphenyl)propanoate biosynthesis|3-(3-hydroxyphenyl)propanoate formation							yaf	2013-01-16T11:47:21Z					biological_process											owl:Class	
GO:0009749	biolink:NamedThing	response to glucose	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucose stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to glucose stimulus													biological_process											owl:Class	
GO:0070379	biolink:NamedThing	high mobility group box 1 binding	Binding to high mobility group box 1 (HMBGB1).	tmpzr1t_l9r_go_relaxed.owl	HMGB1 binding													molecular_function											owl:Class	
GO:0047513	biolink:NamedThing	1,2-alpha-L-fucosidase activity	Catalysis of the reaction: H2O + methyl-2-alpha-L-fucopyranosyl-beta-D-galactoside = L-fucose + methyl beta-D-galactoside.	tmpzr1t_l9r_go_relaxed.owl	almond emulsin fucosidase II activity|2-alpha-L-fucopyranosyl-beta-D-galactoside fucohydrolase activity|almond emulsin fucosidase activity|alpha-(1->2)-L-fucosidase activity				EC:3.2.1.63|RHEA:10816|MetaCyc:12-ALPHA-L-FUCOSIDASE-RXN									molecular_function											owl:Class	
GO:0070776	biolink:NamedThing	MOZ/MORF histone acetyltransferase complex	A histone acetyltransferase complex that has histone H3 acetyltransferase and coactivator activities. Subunits of the human complex include MYST3/MOZ, MYST4/MORF, ING5, EAF6 and one of BRPF1, BRD1/BRPF2 and BRPF3.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-07-02T12:06:04Z					cellular_component											owl:Class	
GO:0047846	biolink:NamedThing	deoxynucleotide 3'-phosphatase activity	Catalysis of the reaction: a deoxynucleoside 3'-phosphate + H2O = a deoxynucleoside + phosphate.	tmpzr1t_l9r_go_relaxed.owl	3'-deoxyribonucleotidase activity|3'-deoxynucleotidase activity|deoxyribonucleotide 3'-phosphohydrolase activity				MetaCyc:DEOXYNUCLEOTIDE-3-PHOSPHATASE-RXN|EC:3.1.3.34|RHEA:10092									molecular_function											owl:Class	
GO:1905075	biolink:NamedThing	positive regulation of tight junction disassembly	Any process that activates or increases the frequency, rate or extent of tight junction disassembly.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of occluding cell junction disassembly|activation of occluding cell junction disassembly|upregulation of tight junction disassembly|up-regulation of tight junction disassembly|up regulation of occluding cell junction disassembly|upregulation of occluding cell junction disassembly|positive regulation of occluding junction disassembly|activation of occluding junction disassembly|activation of tight junction disassembly|up-regulation of occluding cell junction disassembly|up regulation of tight junction disassembly							rl	2016-03-23T19:33:10Z					biological_process											owl:Class	
GO:0070788	biolink:NamedThing	conidiophore stalk development	The process whose specific outcome is the progression of the conidiophore stalk over time, from its formation to the mature structure. The conidiophore stalk is part of a specialized hypha that extends aerially from the growth substrate and supports structures from which conidia, or asexual spores, develop.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-07-08T01:31:44Z					biological_process											owl:Class	
GO:0015970	biolink:NamedThing	guanosine tetraphosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of guanine tetraphosphate (5'-ppGpp-3'), a derivative of guanine riboside with four phosphates.	tmpzr1t_l9r_go_relaxed.owl	guanosine tetraphosphate (5'-ppGpp-3') biosynthesis|guanosine tetraphosphate anabolism|guanosine tetraphosphate synthesis|guanosine tetraphosphate (5'-ppGpp-3') biosynthetic process|guanosine tetraphosphate formation|guanosine tetraphosphate biosynthesis													biological_process											owl:Class	
GO:0033715	biolink:NamedThing	nucleoside oxidase activity	Catalysis of the reactions: inosine + O2 = 9-riburonosylhypoxanthine + 2 H2O; (1a) 2 inosine + O2 = 2 5'-dehydroinosine + 2 H2O, and (1b) 2 5'-dehydroinosine + O2 = 2 9-riburonosylhypoxanthine + 2 H2O.	tmpzr1t_l9r_go_relaxed.owl	nucleoside:oxygen 5'-oxidoreductase activity				EC:1.1.3.28|RHEA:28651|MetaCyc:NUCLEOSIDE-OXIDASE-RXN									molecular_function											owl:Class	
GO:1901061	biolink:NamedThing	guaiacyl lignin metabolic process	The chemical reactions and pathways involving guaiacyl lignin.	tmpzr1t_l9r_go_relaxed.owl	G-lignin metabolic process|guaiacyl lignin metabolism							tt	2012-06-29T02:46:39Z					biological_process											owl:Class	
GO:0008936	biolink:NamedThing	nicotinamidase activity	Catalysis of the reaction: nicotinamide + H2O = nicotinate + NH3.	tmpzr1t_l9r_go_relaxed.owl	YNDase activity|nicotinamide amidohydrolase activity|nicotinamide amidase activity|nicotinamide deaminase activity|NAMase activity|nicotine deamidase activity				EC:3.5.1.19|RHEA:14545|MetaCyc:NICOTINAMID-RXN									molecular_function											owl:Class	
GO:2001139	biolink:NamedThing	negative regulation of phospholipid transport	Any process that stops, prevents or reduces the frequency, rate or extent of phospholipid transport.	tmpzr1t_l9r_go_relaxed.owl								kmv	2011-10-14T06:16:11Z					biological_process											owl:Class	
GO:0016426	biolink:NamedThing	tRNA (adenine) methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing methyladenine.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0102946	biolink:NamedThing	soyasapogenol E UDP-glucosyltransferase activity	Catalysis of the reaction: UDP-alpha-D-glucose + soyasapogenol E <=> UDP + a soyasapogenol E monoglucoside.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-9038									molecular_function											owl:Class	
GO:0033651	biolink:NamedThing	host cell plastid	Any member of a family of organelles as found in the cytoplasm of host cells, which are membrane-bounded and contain DNA. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0120149	biolink:NamedThing	host cell peroxisome	A small host cell organelle enclosed by a single membrane, and found in most eukaryotic cells. Contains peroxidases and other enzymes involved in a variety of metabolic processes including free radical detoxification, lipid catabolism and biosynthesis, and hydrogen peroxide metabolism.	tmpzr1t_l9r_go_relaxed.owl	host peroxisome							krc	2018-04-13T15:36:40Z					cellular_component											owl:Class	
GO:0018746	biolink:NamedThing	phenanthrene-3,4-epoxide hydrolase activity	Catalysis of the reaction: phenanthrene-3,4-oxide + H2O = trans-3,4-dihydrodiolphenanthrene.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0535									molecular_function											owl:Class	
GO:0046712	biolink:NamedThing	GDP catabolic process	The chemical reactions and pathways resulting in the breakdown of GDP, guanosine 5'-diphosphate.	tmpzr1t_l9r_go_relaxed.owl	GDP catabolism|GDP degradation|GDP breakdown													biological_process											owl:Class	
GO:0047126	biolink:NamedThing	N5-(carboxyethyl)ornithine synthase activity	Catalysis of the reaction: N(5)-[1(S)-1-carboxyethyl]-L-ornithine + H(2)O + NADP(+) = L-ornithine + H(+) + NADPH + pyruvate.	tmpzr1t_l9r_go_relaxed.owl	N5-(L-1-carboxyethyl)-L-ornithine:NADP+ oxidoreductase (L-ornithine-forming)|5-N-(L-1-carboxyethyl)-L-ornithine:NADP+ oxidoreductase (L-ornithine-forming)				MetaCyc:1.5.1.24-RXN|EC:1.5.1.24|KEGG_REACTION:R00666|RHEA:18661									molecular_function											owl:Class	
GO:0005722	biolink:NamedThing	beta-heterochromatin	A diffusely banded region of heterochromatin located between euchromatin and alpha-heterochromatin in the polytene chromosome chromocenter; normally replicated during polytenization.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0031413	biolink:NamedThing	regulation of buoyancy	Any process that modulates an organism's tendency or ability to rise or float in a fluid medium such as water or air, often through the use of stored gases.	tmpzr1t_l9r_go_relaxed.owl	buoyancy regulation													biological_process											owl:Class	
GO:0050267	biolink:NamedThing	rubber cis-polyprenylcistransferase activity	Catalysis of the reaction: poly-cis-polyprenyl diphosphate + isopentenyl diphosphate = diphosphate + a poly-cis-polyprenyl diphosphate longer by one C5 unit.	tmpzr1t_l9r_go_relaxed.owl	cis-prenyl transferase activity|rubber polymerase activity|isopentenyl pyrophosphate cis-1,4-polyisoprenyl transferase activity|rubber allyltransferase activity|rubber prenyltransferase activity|poly-cis-polyprenyl-diphosphate:isopentenyl-diphosphate polyprenylcistransferase activity|rubber transferase activity				EC:2.5.1.20|RHEA:18801|MetaCyc:2.5.1.20-RXN									molecular_function											owl:Class	
GO:0015504	biolink:NamedThing	cytosine:proton symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: cytosine(out) + H+(out) = cytosine(in) + H+(in).	tmpzr1t_l9r_go_relaxed.owl	cytosine permease activity|cytosine:hydrogen ion symporter activity													molecular_function											owl:Class	
GO:0005952	biolink:NamedThing	cAMP-dependent protein kinase complex	An enzyme complex, composed of regulatory and catalytic subunits, that catalyzes protein phosphorylation. Inactive forms of the enzyme have two regulatory chains and two catalytic chains; activation by cAMP produces two active catalytic monomers and a regulatory dimer.	tmpzr1t_l9r_go_relaxed.owl	cyclic AMP-dependent protein kinase complex|adenosine 3',5'-cyclophosphate-dependent protein kinase complex|3',5' cAMP-dependent protein kinase complex|PKA|3',5'-cAMP-dependent protein kinase complex													cellular_component											owl:Class	
GO:0035364	biolink:NamedThing	thymine transport	The directed movement of thymine, 5-methyluracil, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	thymine transmembrane transport|5-methyluracil transport							bf	2010-03-11T10:20:24Z					biological_process											owl:Class	
GO:0050744	biolink:NamedThing	protein-FMN linkage via 3'-(8alpha-FMN)-L-histidine	The formation of a protein-FMN linkage via 3'-(8alpha-FMN)-L-histidine.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0353									biological_process											owl:Class	
GO:0035896	biolink:NamedThing	positive regulation of mast cell degranulation in other organism	Any process in which an organism increases the frequency, rate or extent of blood mast cell degranulation in another organism.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of mast cell degranulation in other organism|upregulation of mast cell degranulation in other organism							bf	2011-06-15T02:49:03Z					biological_process											owl:Class	
GO:0070543	biolink:NamedThing	response to linoleic acid	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a linoleic acid stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to linoleate													biological_process											owl:Class	
GO:0001079	biolink:NamedThing	nitrogen catabolite regulation of transcription from RNA polymerase II promoter	A transcription regulation process in which the presence of one nitrogen source leads to the modulation of the frequency, rate, or extent of transcription, from an RNA polymerase II promoter, of specific genes involved in the metabolism of other nitrogen sources.	tmpzr1t_l9r_go_relaxed.owl	regulation of transcription from RNA polymerase II promoter by nitrogen catabolites							krc	2010-10-27T03:29:01Z					biological_process											owl:Class	
GO:1904885	biolink:NamedThing	beta-catenin destruction complex assembly	The aggregation, arrangement and bonding together of a set of components to form a beta-catenin destruction complex.	tmpzr1t_l9r_go_relaxed.owl	beta-catenin degradation complex formation|beta-catenin destruction complex formation|APC-Axin-1-beta-catenin complex formation|Axin-APC-beta-catenin-GSK3B complex formation|23S APC complex formation|BDC formation|beta-catenin degradation complex assembly|APC-Axin-1-beta-catenin complex assembly|Axin-APC-beta-catenin-GSK3B complex assembly|BDC assembly|destruction complex formation|23S APC complex assembly							bf	2016-01-05T11:40:55Z					biological_process											owl:Class	
GO:0036342	biolink:NamedThing	post-anal tail morphogenesis	The process in which a post-anal tail is generated and organized. A post-anal tail is a muscular region of the body that extends posterior to the anus. The post-anal tail may aid locomotion and balance.	tmpzr1t_l9r_go_relaxed.owl								bf	2012-09-11T13:54:49Z					biological_process											owl:Class	
GO:0009134	biolink:NamedThing	nucleoside diphosphate catabolic process	The chemical reactions and pathways resulting in the breakdown of a nucleoside diphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with diphosphate on the sugar.	tmpzr1t_l9r_go_relaxed.owl	nucleoside diphosphate degradation|nucleoside diphosphate breakdown|nucleoside diphosphate catabolism													biological_process											owl:Class	
GO:0035020	biolink:NamedThing	regulation of Rac protein signal transduction	Any process that modulates the frequency, rate or extent of Rac protein signal transduction.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0051558	biolink:NamedThing	phlobaphene metabolic process	The chemical reactions and pathways involving phlobaphenes, red pigments with oligomeric or polymeric structure derived from the flavonoid intermediate flavan-4-ols.	tmpzr1t_l9r_go_relaxed.owl	phlobaphene metabolism													biological_process											owl:Class	
GO:0061270	biolink:NamedThing	mesonephric intraglomerular mesangial cell proliferation	The multiplication or reproduction of intraglomerular glomerular mesangium cells in the mesonephros by cell division, resulting in the expansion of their population. Intraglomerular mesangial cells are specialized pericytes located among the glomerular capillaries within a renal corpuscle of a kidney. They are required for filtration, structural support and phagocytosis.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-08-30T03:23:10Z					biological_process											owl:Class	
GO:1900213	biolink:NamedThing	positive regulation of mesenchymal cell apoptotic process involved in metanephros development	Any process that activates or increases the frequency, rate or extent of mesenchymal cell apoptotic process involved in metanephros development.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of mesenchymal cell apoptosis involved in metanephros development|activation of mesenchymal cell apoptosis involved in metanephros development|positive regulation of mesenchymal cell apoptosis involved in metanephros development|upregulation of mesenchymal cell apoptosis involved in metanephros development|up regulation of mesenchymal cell apoptosis involved in metanephros development							yaf	2012-03-22T10:53:09Z					biological_process											owl:Class	
GO:1901833	biolink:NamedThing	all-trans-neoxanthin biosynthetic process	The chemical reactions and pathways resulting in the formation of all-trans-neoxanthin.	tmpzr1t_l9r_go_relaxed.owl	neoxanthin anabolism|neoxanthin formation|neoxanthin biosynthesis|neoxanthin synthesis|all-trans-neoxanthin anabolism|all-trans-neoxanthin synthesis|neoxanthin biosynthetic process|all-trans-neoxanthin biosynthesis|all-trans-neoxanthin formation							yaf	2013-01-22T12:43:56Z					biological_process											owl:Class	
GO:0099182	biolink:NamedThing	presynaptic intermediate filament cytoskeleton	The intermediate filament cytoskeleton that is part of a presynapse.	tmpzr1t_l9r_go_relaxed.owl								dos	2017-12-01T18:10:21Z					cellular_component											owl:Class	
GO:0047905	biolink:NamedThing	fructose-6-phosphate phosphoketolase activity	Catalysis of the reaction: D-fructose 6-phosphate + phosphate = acetyl phosphate + D-erythrose 4-phosphate + H2O.	tmpzr1t_l9r_go_relaxed.owl	D-fructose-6-phosphate D-erythrose-4-phosphate-lyase (adding phosphate; acetyl-phosphate-forming)|D-fructose-6-phosphate D-erythrose-4-phosphate-lyase (phosphate-acetylating) activity				EC:4.1.2.22|MetaCyc:FRUCTOSE-6-PHOSPHATE-PHOSPHOKETOLASE-RXN|RHEA:12196									molecular_function											owl:Class	
GO:0070416	biolink:NamedThing	trehalose metabolism in response to water deprivation	The chemical reactions and pathways involving trehalose that occur as a result of deprivation of water.	tmpzr1t_l9r_go_relaxed.owl	trehalose metabolic process involved in response to water deprivation													biological_process											owl:Class	
GO:0031607	biolink:NamedThing	nuclear proteasome core complex, beta-subunit complex	The subunits forming the inner ring of the core complex of a proteasome located in the nucleus of a cell.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0047231	biolink:NamedThing	pyridoxine 5'-O-beta-D-glucosyltransferase activity	Catalysis of the reaction: pyridoxine + UDP-D-glucose = 5'-O-beta-D-glucosylpyridoxine + H(+) + UDP.	tmpzr1t_l9r_go_relaxed.owl	UDPglucose:pyridoxine 5'-O-beta-D-glucosyltransferase activity|UDP-glucose:pyridoxine 5'-O-beta-D-glucosyltransferase activity|UDP-glucose-pyridoxine glucosyltransferase activity|UDP-glucose:pyridoxine 5'-O-beta-glucosyltransferase activity|uridine diphosphoglucose-pyridoxine 5'-beta-glucosyltransferase activity				RHEA:20177|KEGG_REACTION:R01912|EC:2.4.1.160|MetaCyc:2.4.1.160-RXN									molecular_function											owl:Class	
GO:0036004	biolink:NamedThing	GAF domain binding	Binding to a GAF protein domain.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-09-20T04:20:42Z					molecular_function											owl:Class	
GO:0019937	biolink:NamedThing	protein catenane formation via N6-(L-isoaspartyl)-L-lysine, autocatalytic	The autocatalytic formation of isopeptide bonds by ligation of peptidyl-lysine and peptidyl-asparagine residues; known to occur in the capsid of some bacteriophage, such as HK97, where it is thought to provide a mechanism for stabilizing the capsid.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0294									biological_process											owl:Class	
GO:0018419	biolink:NamedThing	protein catenane formation	The aggregation, arrangement and bonding together of a protein structure comprising two or more rings that are interlocked but not covalently joined; resembling the links of a chain.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0006052	biolink:NamedThing	N-acetylmannosamine biosynthetic process	The chemical reactions and pathways resulting in the formation of N-acetylmannosamine, the acetylated derivative of mannosamine, 2-amino-2-deoxymannose.	tmpzr1t_l9r_go_relaxed.owl	N-acetylmannosamine anabolism|N-acetylmannosamine formation|N-acetylmannosamine synthesis|N-acetylmannosamine biosynthesis													biological_process											owl:Class	
GO:0062056	biolink:NamedThing	compound eye pigment cell differentiation	The process in which a relatively unspecialized cell acquires the specialized features of a compound eye pigment cell, a cell of the retina containing screening pigments that functions to screen photoreceptors from light leaking from adjacent ommatidia.	tmpzr1t_l9r_go_relaxed.owl								dph	2018-08-01T12:59:42Z					biological_process											owl:Class	
GO:0047973	biolink:NamedThing	guanidinoacetate kinase activity	Catalysis of the reaction: ATP + guanidinoacetate = ADP + 2 H(+) + phosphoguanidinoacetate.	tmpzr1t_l9r_go_relaxed.owl	guanidoacetate kinase activity|glycocyamine kinase activity|ATP:guanidinoacetate N-phosphotransferase activity				MetaCyc:GUANIDOACETATE-KINASE-RXN|EC:2.7.3.1|RHEA:14145|KEGG_REACTION:R02575									molecular_function											owl:Class	
GO:1904616	biolink:NamedThing	regulation of actin binding	Any process that modulates the frequency, rate or extent of actin binding.	tmpzr1t_l9r_go_relaxed.owl	regulation of membrane associated actin binding							mr	2015-08-27T19:08:56Z					biological_process											owl:Class	
GO:0016989	biolink:NamedThing	sigma factor antagonist activity	The function of binding to a sigma factor and stopping, preventing or reducing the rate of its transcriptional activity.	tmpzr1t_l9r_go_relaxed.owl	anti-sigma factor activity													molecular_function											owl:Class	
GO:0036169	biolink:NamedThing	3-methoxy-4-hydroxy-5-decaprenylbenzoic acid decarboxylase activity	Catalysis of the reaction: 3-methoxy-4-hydroxy-5-decaprenylbenzoic acid -> 2-methoxy-6-decaprenylphenol + CO2.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-2162195			bf	2012-03-27T04:47:47Z					molecular_function											owl:Class	
GO:0031826	biolink:NamedThing	type 2A serotonin receptor binding	Binding to a type 2A serotonin receptor.	tmpzr1t_l9r_go_relaxed.owl	type 2A serotonin receptor ligand|5-hydroxytryptamine 2A receptor binding													molecular_function											owl:Class	
GO:0032194	biolink:NamedThing	ubiquinone biosynthetic process via 3,4-dihydroxy-5-polyprenylbenzoate	The chemical reactions and pathways resulting in the formation of ubiquinone, via the intermediates 3,4-dihydroxy-5-polyprenylbenzoate and 3-methoxy-4-hydroxy-5-polyprenylbenzoate.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0047702	biolink:NamedThing	beta-lysine 5,6-aminomutase activity	Catalysis of the reaction: (3S)-3,6-diaminohexanoate = (3S,5S)-3,5-diaminohexanoate.	tmpzr1t_l9r_go_relaxed.owl	(3S)-3,6-diaminohexanoate 5,6-aminomutase activity|b-lysine 5,6-aminomutase activity|L-beta-lysine 5,6-aminomutase activity|beta-lysine mutase activity				RHEA:21736|MetaCyc:BETA-LYSINE-56-AMINOMUTASE-RXN|EC:5.4.3.3|KEGG_REACTION:R03275									molecular_function											owl:Class	
GO:0035995	biolink:NamedThing	detection of muscle stretch	The series of events by which a muscle stretch stimulus is received by a cell and converted into a molecular signal.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-08-30T01:53:35Z					biological_process											owl:Class	
GO:0035994	biolink:NamedThing	response to muscle stretch	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a myofibril being extended beyond its slack length.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-08-30T01:52:31Z					biological_process											owl:Class	
GO:1990933	biolink:NamedThing	microtubule cytoskeleton attachment to nuclear envelope	A process in which the microtubule cytoskeleton is attached to the nuclear envelope.	tmpzr1t_l9r_go_relaxed.owl								vw	2016-03-17T08:32:37Z					biological_process											owl:Class	
GO:1901485	biolink:NamedThing	positive regulation of transcription factor catabolic process	Any process that activates or increases the frequency, rate or extent of transcription factor catabolic process.	tmpzr1t_l9r_go_relaxed.owl	activation of transcription factor degradation|activation of proteasome-mediated transcription factor catabolism|upregulation of transcription factor catabolism|up regulation of transcription factor catabolism|up-regulation of proteasome-mediated transcription factor catabolism|upregulation of transcription factor breakdown|positive regulation of transcription factor degradation|up-regulation of transcription factor catabolism|up regulation of sequence-specific DNA binding transcription factor catabolic process|activation of sequence-specific DNA binding transcription factor catabolic process|up-regulation of transcription factor catabolic process|activation of transcription factor breakdown|up regulation of transcription factor degradation|positive regulation of proteasome-mediated transcription factor catabolism|activation of transcription factor catabolic process|upregulation of transcription factor catabolic process|up-regulation of transcription factor breakdown|upregulation of proteasome-mediated transcription factor catabolism|upregulation of transcription factor degradation|up regulation of proteasome-mediated transcription factor catabolism|up regulation of transcription factor catabolic process|positive regulation of sequence-specific DNA binding transcription factor catabolic process|activation of transcription factor catabolism|positive regulation of transcription factor catabolism|up-regulation of transcription factor degradation|positive regulation of transcription factor breakdown|up-regulation of sequence-specific DNA binding transcription factor catabolic process|up regulation of transcription factor breakdown|upregulation of sequence-specific DNA binding transcription factor catabolic process							bf	2012-10-08T09:03:27Z					biological_process											owl:Class	
GO:0090416	biolink:NamedThing	nicotinate transmembrane transporter activity	Enables the transfer of nicotinate from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-8869603			tb	2011-10-19T11:09:59Z					molecular_function											owl:Class	
GO:0043295	biolink:NamedThing	glutathione binding	Binding to glutathione; a tripeptide composed of the three amino acids cysteine, glutamic acid and glycine.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0033950	biolink:NamedThing	xyloglucan-specific exo-beta-1,4-glucanase activity	Catalysis of the reaction: xyloglucan + H2O = xyloglucan oligosaccharides. This reaction is the exohydrolysis of 1,4-beta-D-glucosidic linkages in xyloglucan.	tmpzr1t_l9r_go_relaxed.owl	Cel74A|[(1->6)-alpha-D-xylo]-(1->4)-beta-D-glucan exo-glucohydrolase activity				EC:3.2.1.155|MetaCyc:3.2.1.155-RXN									molecular_function											owl:Class	
GO:0043774	biolink:NamedThing	coenzyme F420-2 alpha-glutamyl ligase activity	Catalysis of the reaction: coenzyme F420-2 + L-glutamate + GTP = coenzyme F420-3 + GDP + orthophosphate.	tmpzr1t_l9r_go_relaxed.owl	F420-2 alpha-glutamyl ligase activity				RHEA:42332|EC:6.3.2.32									molecular_function											owl:Class	
GO:0003055	biolink:NamedThing	circadian regulation of heart rate by the suprachiasmatic nucleus	The process in which the suprachiasmatic nucleus modulates heart rate at different values with a regularity of approximately 24 hours.	tmpzr1t_l9r_go_relaxed.owl	circadian regulation of heart contraction rate by the suprachiasmatic nucleus|SCN regulation of heart rate|master pacemaker clock regulation of heart rate													biological_process											owl:Class	
GO:0003053	biolink:NamedThing	circadian regulation of heart rate	Any process in which an organism modulates its heart rate at different values with a regularity of approximately 24 hours.	tmpzr1t_l9r_go_relaxed.owl	circadian regulation of heart contraction rate													biological_process											owl:Class	
GO:1903841	biolink:NamedThing	cellular response to arsenite(3-)	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an arsenite(3-) stimulus.	tmpzr1t_l9r_go_relaxed.owl								mr	2015-01-22T19:49:35Z					biological_process											owl:Class	
GO:1903843	biolink:NamedThing	cellular response to arsenite ion	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an arsenite ion stimulus.	tmpzr1t_l9r_go_relaxed.owl								mr	2015-01-22T19:56:14Z					biological_process											owl:Class	
GO:0044025	biolink:NamedThing	histone kinase activity (H2B-S14 specific)	Catalysis of the transfer of a phosphate group to the serine-14 or an equivalent residue of the N-terminal tail of histone H2B.	tmpzr1t_l9r_go_relaxed.owl	histone serine kinase activity (H2B-S14 specific)|histone-serine kinase activity (H2B-S14 specific)													molecular_function											owl:Class	
GO:1904766	biolink:NamedThing	negative regulation of macroautophagy by TORC1 signaling	A TORC1 signaling that results in negative regulation of macroautophagy.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of autophagy in response to cellular starvation by TORC1 signaling|negative regulation of non-specific autophagy by TORC1 signaling|negative regulation of starvation-induced autophagy by TORC1 signaling|negative regulation of macroautophagy by TORC1 signal transduction|negative regulation of starvation-induced autophagy by TORC1 signal transduction|negative regulation of autophagy in response to cellular starvation by TORC1 signal transduction|negative regulation of non-specific autophagy by TORC1 signal transduction							dph	2015-10-26T18:34:47Z					biological_process											owl:Class	
GO:0102481	biolink:NamedThing	3D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase activity	Catalysis of the reaction: 3D-3,5/4-trihydroxycyclohexane-1,2-dione + H2O <=> 5-deoxy-D-glucuronate + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-14149|EC:3.7.1.22|RHEA:25836									molecular_function											owl:Class	
GO:0034076	biolink:NamedThing	cucurbitadienol synthase activity	Catalysis of the reaction: oxidosqualene = cucurbitadienol.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0021888	biolink:NamedThing	hypothalamus gonadotrophin-releasing hormone neuron development	The process whose specific outcome is the progression of a hypothalamus gonadotrophin-releasing hormone neuron over time, from initial commitment of its fate, to the fully functional differentiated cell.	tmpzr1t_l9r_go_relaxed.owl	hypothalamus gonadotropin-releasing hormone neuron development													biological_process											owl:Class	
GO:0021884	biolink:NamedThing	forebrain neuron development	The process whose specific outcome is the progression of a neuron that resides in the forebrain, from its initial commitment to its fate, to the fully functional differentiated cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1900477	biolink:NamedThing	negative regulation of G1/S transition of mitotic cell cycle by negative regulation of transcription from RNA polymerase II promoter	Any process that stops, prevents, or reduces the frequency, rate or extent of G1/S transition of mitotic cell cycle by stopping, preventing, or reducing the frequency, rate or extent of transcription from an RNA polymerase II promoter.	tmpzr1t_l9r_go_relaxed.owl								dgf	2012-05-01T09:01:04Z					biological_process											owl:Class	
GO:0070007	biolink:NamedThing	glutamic-type endopeptidase activity	Catalysis of the hydrolysis of internal peptide bonds in a polypeptide chain by a mechanism involving a glutamate/glutamine catalytic dyad.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0019308	biolink:NamedThing	dTDP-mannose biosynthetic process	The chemical reactions and pathways resulting in the formation of dTDP-mannose, a substance composed of mannose in glycosidic linkage with deoxyribosylthymine diphosphate.	tmpzr1t_l9r_go_relaxed.owl	dTDP-mannose synthesis|dTDP-mannose formation|dTDP-mannose biosynthesis|dTDP-mannose anabolism													biological_process											owl:Class	
GO:0061403	biolink:NamedThing	positive regulation of transcription from RNA polymerase II promoter in response to nitrosative stress	Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a nitrosative stress stimulus. Nitrosative stress is a state often resulting from exposure to high levels of nitric oxide (NO) or the highly reactive oxidant peroxynitrite, which is produced following interaction of NO with superoxide anions.	tmpzr1t_l9r_go_relaxed.owl								dph	2012-01-10T03:15:30Z					biological_process											owl:Class	
GO:0031860	biolink:NamedThing	telomeric 3' overhang formation	The formation of the single stranded telomeric 3' overhang, a conserved feature that ranges in length from 12 nt in budding yeast to approximately 500 nt in humans.	tmpzr1t_l9r_go_relaxed.owl	telomere 3'-end processing|telomere end processing													biological_process											owl:Class	
GO:0018077	biolink:NamedThing	protein iodination	The addition of one or more iodine atoms to an amino acid residue in a protein.	tmpzr1t_l9r_go_relaxed.owl	protein amino acid iodination													biological_process											owl:Class	
GO:0000403	biolink:NamedThing	Y-form DNA binding	Binding to a DNA segment shaped like a Y. This shape occurs when DNA contains a region of paired double-stranded DNA on one end and a region of unpaired DNA strands on the opposite end.	tmpzr1t_l9r_go_relaxed.owl	forked DNA binding|splayed Y-form DNA binding													molecular_function											owl:Class	
GO:0034816	biolink:NamedThing	anthracene 9,10-dioxygenase activity	Catalysis of the reaction: anthracene + 2 H2O = cis-9,10-dihydroanthracene-9,10-diol.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r1141									molecular_function											owl:Class	
GO:0046175	biolink:NamedThing	aldonic acid biosynthetic process	The chemical reactions and pathways resulting in the formation of aldonic acid, a monocarboxylic acid with a chain of three or more carbon atoms, derived from an aldose by oxidation of the aldehydic group.	tmpzr1t_l9r_go_relaxed.owl	aldonic acid formation|aldonic acid biosynthesis|aldonic acid synthesis|aldonic acid anabolism													biological_process											owl:Class	
GO:0033779	biolink:NamedThing	5beta-cholestane-3alpha,7alpha-diol 12alpha-hydroxylase activity	Catalysis of the reaction: 5beta-cholestane-3alpha,7alpha-diol + H(+) + NADPH + O(2) = 5beta-cholestane-3alpha,7alpha,12alpha-triol + H(2)O + NADP(+).	tmpzr1t_l9r_go_relaxed.owl	sterol 12alpha-hydroxylase activity|cytochrome P450 8B1|5beta-cholestane-3alpha,7alpha-diol,NADPH:oxygen oxidoreductase (12alpha-hydroxylating) activity|5beta-cholestane-3alpha,7alpha-diol 12alpha-monooxygenase activity|CYP8B1				RHEA:15261|MetaCyc:1.14.13.96-RXN|KEGG_REACTION:R07204|EC:1.14.14.139									molecular_function											owl:Class	
GO:0046862	biolink:NamedThing	chromoplast membrane	Either of the lipid bilayers that surround a chromoplast and form the chromoplast envelope.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0051572	biolink:NamedThing	negative regulation of histone H3-K4 methylation	Any process that stops, prevents, or reduces the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 4 of histone H3.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of histone H3-K4 methylation|down regulation of histone H3-K4 methylation|downregulation of histone H3-K4 methylation|inhibition of histone H3-K4 methylation													biological_process											owl:Class	
GO:0071113	biolink:NamedThing	alphaIIb-beta3 integrin-ICAM-4 complex	A protein complex that consists of an alphaIIb-beta3 integrin complex bound to the cell adhesion molecule ICAM-4.	tmpzr1t_l9r_go_relaxed.owl	ITGAIIb-ITGB3-ICAM4 complex							mah	2009-11-13T02:17:59Z					cellular_component											owl:Class	
GO:0052791	biolink:NamedThing	3-deoxy-D-glycero-D-galacto-2-nonulosonic acid hydrolase activity	Catalysis of the reaction: (2-keto-3-deoxynononic acid)n + H2O = (2-keto-3-deoxynononic acid)n-1 + 2-keto-3-deoxynononic acid. This reaction is the hydrolysis of a 2-keto-3-deoxynononic acid residue from a poly-2-keto-3-deoxynononic acid chain.	tmpzr1t_l9r_go_relaxed.owl	2-keto-3-deoxynononic acid sialidase activity							ai	2011-10-04T04:53:49Z					molecular_function											owl:Class	
GO:0016997	biolink:NamedThing	alpha-sialidase activity	Catalysis of the hydrolysis of alpha-glycosidic linkages in oligo- or poly(sialic) acids.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1901949	biolink:NamedThing	5alpha,9alpha,10beta-labda-8(20),13-dien-15-yl diphosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of 5alpha,9alpha,10beta-labda-8(20),13-dien-15-yl diphosphate.	tmpzr1t_l9r_go_relaxed.owl	5alpha,9alpha,10beta-labda-8(20),13-dien-15-yl diphosphate synthesis|5alpha,9alpha,10beta-labda-8(20),13-dien-15-yl diphosphate biosynthesis|5alpha,9alpha,10beta-labda-8(20),13-dien-15-yl diphosphate anabolism|5alpha,9alpha,10beta-labda-8(20),13-dien-15-yl diphosphate formation							ms	2013-02-18T15:50:50Z					biological_process											owl:Class	
GO:0080189	biolink:NamedThing	primary growth	Growth of a plant structure from the time of its initiation by an apical meristem until its expansion is completed.	tmpzr1t_l9r_go_relaxed.owl						Has its inception in the apical meristems (PO:0020144) and continues in their derivative meristems - protoderm (PO:0006210) and procambium (PO:0025275) - even in older tissues. Primary and secondary growth can occur simultaneously in the same organism.		dhl	2012-12-06T15:20:41Z					biological_process											owl:Class	
GO:0008210	biolink:NamedThing	estrogen metabolic process	The chemical reactions and pathways involving estrogens, C18 steroid hormones that can stimulate the development of female sexual characteristics. Also found in plants.	tmpzr1t_l9r_go_relaxed.owl	oestrogen metabolic process|oestrogen metabolism|estrogen metabolism													biological_process											owl:Class	
GO:0031851	biolink:NamedThing	kappa-type opioid receptor binding	Binding to a kappa-type opioid receptor.	tmpzr1t_l9r_go_relaxed.owl	kappa-type opioid receptor ligand|dynorphin receptor binding													molecular_function											owl:Class	
GO:0003863	biolink:NamedThing	3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity	Catalysis of the reaction: 3-methyl-2-oxobutanoate + lipoamide = S-(2-methylpropanoyl)dihydrolipoamide + CO2.	tmpzr1t_l9r_go_relaxed.owl	alpha-keto-alpha-methylvalerate dehydrogenase activity|3-methyl-2-oxobutanoate:dihydrolipoyllysine-residue (2-methylpropanoyl)transferase-lipoyllysine 2-oxidoreductase (decarboxylating, acceptor-2-methylpropanoylating)|2-oxoisocaproate dehydrogenase activity|dehydrogenase, branched chain alpha-keto acid activity|BCKDH activity|3-methyl-2-oxobutanoate:lipoamide oxidoreductase (decarboxylating and acceptor-2-methylpropanoylating) activity|branched-chain alpha-keto acid dehydrogenase activity|branched-chain keto acid dehydrogenase activity|alpha-oxoisocaproate dehydrogenase activity|dehydrogenase, 2-oxoisovalerate (lipoate) activity|3-methyl-2-oxobutanoate dehydrogenase (lipoamide) activity|branched chain keto acid dehydrogenase activity|branched-chain (-2-oxoacid) dehydrogenase (BCD) activity|branched-chain ketoacid dehydrogenase activity|alpha-ketoisocaproic dehydrogenase activity|alpha-ketoisovalerate dehydrogenase activity|branched-chain 2-keto acid dehydrogenase activity|alpha-ketoisocaproic-alpha-keto-alpha-methylvaleric dehydrogenase activity|branched-chain 2-oxo acid dehydrogenase activity|branched-chain alpha-oxo acid dehydrogenase activity|2-oxoisovalerate (lipoate) dehydrogenase activity|alpha-ketoacid dehydrogenase activity|alpha-ketoisocaproate dehydrogenase activity|BCOAD activity	https://github.com/geneontology/go-ontology/issues/21144			EC:1.2.4.4|RHEA:13457|MetaCyc:1.2.4.4-RXN							GO:0003826		molecular_function											owl:Class	
GO:1904160	biolink:NamedThing	protein localization to chloroplast starch grain	A process in which a protein is transported to, or maintained in, a location within a chloroplast starch grain.	tmpzr1t_l9r_go_relaxed.owl	protein localisation to chloroplast starch grain|protein localisation in chloroplast starch grain|protein localization in chloroplast starch grain							lr	2015-04-20T18:06:17Z					biological_process											owl:Class	
GO:1904066	biolink:NamedThing	G protein-coupled receptor signaling pathway involved in dauer larval development	Any G protein-coupled receptor signaling pathway that is involved in dauer larval development.	tmpzr1t_l9r_go_relaxed.owl	GPCR signaling pathway involved in dauer larval development|G protein coupled receptor protein signalling pathway involved in dauer larval development|G-protein coupled receptor protein signal transduction involved in dauer larval development|GPCR signalling pathway involved in dauer larval development|G-protein-coupled receptor protein signalling pathway involved in dauer larval development|G protein coupled receptor protein signaling pathway involved in dauer larval development|G-protein coupled receptor protein signaling pathway involved in dauer larval development|G-protein coupled receptor signalling pathway involved in dauer larval development							kmv	2015-03-20T00:51:06Z					biological_process											owl:Class	
GO:0031960	biolink:NamedThing	response to corticosteroid	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a corticosteroid hormone stimulus. A corticosteroid is a steroid hormone that is produced in the adrenal cortex. Corticosteroids are involved in a wide range of physiologic systems such as stress response, immune response and regulation of inflammation, carbohydrate metabolism, protein catabolism, blood electrolyte levels, and behavior. They include glucocorticoids and mineralocorticoids.	tmpzr1t_l9r_go_relaxed.owl	response to corticosteroid stimulus													biological_process											owl:Class	
GO:0009717	biolink:NamedThing	isoflavonoid biosynthetic process	The chemical reactions and pathways resulting in the formation of isoflavonoids, a group of water-soluble phenolic derivatives, isomeric with flavonoids.	tmpzr1t_l9r_go_relaxed.owl	isoflavonoid formation|isoflavonoid biosynthesis|isoflavonoid anabolism|isoflavonoid synthesis													biological_process											owl:Class	
GO:0046170	biolink:NamedThing	methanol catabolic process	The chemical reactions and pathways resulting in the breakdown of methanol, CH3-OH, a colorless, flammable, mobile, poisonous liquid, widely used as a solvent.	tmpzr1t_l9r_go_relaxed.owl	methanol breakdown|methanol catabolism|methanol degradation													biological_process											owl:Class	
GO:0005602	biolink:NamedThing	complement component C1 complex	A protein complex composed of six subunits of C1q, each formed of the three homologous polypeptide chains C1QA, C1QB, and C1QB, and tetramer of two C1QR and two C1QS polypeptide chains.	tmpzr1t_l9r_go_relaxed.owl	complement component C1q complex													cellular_component											owl:Class	
GO:0047920	biolink:NamedThing	geissoschizine dehydrogenase activity	Catalysis of the reaction: geissoschizine + NADP(+) = 4,21-dehydrogeissoschizine + H(+) + NADPH.	tmpzr1t_l9r_go_relaxed.owl	geissoschizine:NADP+ 4,21-oxidoreductase activity				MetaCyc:GEISSOSCHIZINE-DEHYDROGENASE-RXN|RHEA:11376|EC:1.3.1.36|KEGG_REACTION:R03860									molecular_function											owl:Class	
GO:0071234	biolink:NamedThing	cellular response to phenylalanine	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a phenylalanine stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-12-03T02:09:36Z					biological_process											owl:Class	
GO:0034024	biolink:NamedThing	glutamate-putrescine ligase activity	Catalysis of the reaction: L-glutamate + ATP + putrescine = gamma-L-glutamylputrescine + ADP + 2 H(+) + phosphate.	tmpzr1t_l9r_go_relaxed.owl	L-glutamate:putrescine ligase (ADP-forming) activity|YcjK|gamma-glutamylputrescine synthetase activity				KEGG_REACTION:R07414|RHEA:13633|EC:6.3.1.11|MetaCyc:RXN0-3901									molecular_function											owl:Class	
GO:0102694	biolink:NamedThing	kinetin UDP glycosyltransferase activity	Catalysis of the reaction: UDP-alpha-D-glucose + kinetin <=> H+ + 9-(alpha-D-glucosyl)kinetin + UDP.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-4732									molecular_function											owl:Class	
GO:0018463	biolink:NamedThing	6-hydroxyhexanoate dehydrogenase activity	Catalysis of the reaction: 6-hydroxyhexanoate + NAD(+) = 6-oxohexanoate + H(+) + NADH.	tmpzr1t_l9r_go_relaxed.owl	6-hydroxyhexanoate:NAD+ oxidoreductase activity				UM-BBD_reactionID:r0174|RHEA:14225|MetaCyc:6-HYDROXYHEXANOATE-OXIDATION-RXN|EC:1.1.1.258|KEGG_REACTION:R05283									molecular_function											owl:Class	
GO:1900696	biolink:NamedThing	negative regulation of N',N'',N'''-triacetylfusarinine C biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of N',N'',N'''-triacetylfusarinine C biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	inhibition of N',N'',N'''-triacetylfusarinine C biosynthetic process|downregulation of N',N'',N'''-triacetylfusarinine C biosynthesis|inhibition of N',N'',N'''-triacetylfusarinine C biosynthesis|down regulation of N',N'',N'''-triacetylfusarinine C formation|down-regulation of N',N'',N'''-triacetylfusarinine C biosynthetic process|down regulation of N',N'',N'''-triacetylfusarinine C biosynthetic process|down-regulation of N',N'',N'''-triacetylfusarinine C formation|down-regulation of N',N'',N'''-triacetylfusarinine C anabolism|down-regulation of N',N'',N'''-triacetylfusarinine C synthesis|downregulation of N',N'',N'''-triacetylfusarinine C biosynthetic process|negative regulation of N',N'',N'''-triacetylfusarinine C synthesis|downregulation of N',N'',N'''-triacetylfusarinine C synthesis|down-regulation of N',N'',N'''-triacetylfusarinine C biosynthesis|inhibition of N',N'',N'''-triacetylfusarinine C synthesis|negative regulation of N',N'',N'''-triacetylfusarinine C biosynthesis|negative regulation of N',N'',N'''-triacetylfusarinine C anabolism|inhibition of N',N'',N'''-triacetylfusarinine C anabolism|downregulation of N',N'',N'''-triacetylfusarinine C formation|downregulation of N',N'',N'''-triacetylfusarinine C anabolism|down regulation of N',N'',N'''-triacetylfusarinine C biosynthesis|inhibition of N',N'',N'''-triacetylfusarinine C formation|down regulation of N',N'',N'''-triacetylfusarinine C anabolism|down regulation of N',N'',N'''-triacetylfusarinine C synthesis|negative regulation of N',N'',N'''-triacetylfusarinine C formation							di	2012-05-22T04:54:45Z					biological_process											owl:Class	
GO:1990206	biolink:NamedThing	jasmonyl-Ile conjugate hydrolase activity	Catalysis of the reaction: jasmonyl-Ile + H2O = jasmonic acid + L-isoleucine.	tmpzr1t_l9r_go_relaxed.owl	JA-Ile hydrolase							tb	2013-10-07T18:37:49Z					molecular_function											owl:Class	
GO:0043541	biolink:NamedThing	UDP-N-acetylglucosamine transferase complex	A multienzyme, heterooligomeric complex involved in dolichyl-linked oligosaccharide synthesis. In yeast the complex is composed of Alg7p, which catalyzes the first step (GlcNAc1-PP-Dol from dolichol-phosphate and UDP-GlcNAc), and Alg13p plus Alg14p, the catalytic and anchoring subunits respectively, which together catalyze the second step (GlcNAc2-PP-dolichol from GlcNAc1-PP-Dol and UDP-GlcNAc) of dolichyl-linked oligosaccharide synthesis.	tmpzr1t_l9r_go_relaxed.owl						See also the molecular function term 'N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity ; GO:0004577'.								cellular_component											owl:Class	
GO:0003945	biolink:NamedThing	N-acetyllactosamine synthase activity	Catalysis of the reaction: UDP-galactose + N-acetyl-D-glucosamine = UDP + N-acetyllactosamine.	tmpzr1t_l9r_go_relaxed.owl	UDP-galactose-acetylglucosamine galactosyltransferase activity|UDP-Gal:N-acetylglucosamine beta-1,4-galactosyltransferase activity|UDPgalactose-N-acetylglucosamine beta-D-galactosyltransferase activity|beta-(1,4)-galactosyltransferase activity|UDP-galactose N-acetylglucosamine beta-4-galactosyltransferase activity|N-acetylglucosamine (beta-1,4)galactosyltransferase activity|Gal-T|UDPgalactose:N-acetyl-D-glucosamine 4-beta-D-galactosyltransferase activity|beta-1,4-GalT|UDP-galactose-N-acetylglucosamine galactosyltransferase activity|acetyllactosamine synthetase activity|UDP-galactose-N-acetylglucosamine beta-D-galactosyltransferase activity|lactosamine synthetase activity|lactose synthetase A protein|UDP-beta-1,4-galactosyltransferase activity|lactosamine synthase activity|UDP-galactose:N-acetyl-D-glucosamine 4-beta-D-galactosyltransferase activity|beta-1,4-galactosyltransferase activity|UDP-galactose:N-acetylglucosaminide beta-1,4-galactosyltransferase activity|uridine diphosphogalactose-acetylglucosamine galactosyltransferase activity|UDP-galactose-N-acetylglucosamine beta-1,4-galactosyltransferase activity|NAL synthetase activity|N-acetylglucosamine beta-(1,4)-galactosyltransferase activity|UDPgalactose:N-acetylglucosaminyl(beta-1,4)galactosyltransferase activity|beta-N-acetylglucosaminide beta-1,4-galactosyltransferase activity|N-acetyllactosamine synthetase activity				RHEA:17745|EC:2.4.1.90|MetaCyc:N-ACETYLLACTOSAMINE-SYNTHASE-RXN									molecular_function											owl:Class	
GO:0071819	biolink:NamedThing	DUBm complex	A protein complex that forms part of SAGA-type complexes SAGA and SLIK, and mediates deubiquitination of histone H2B. In S. cerevisiae, the DUBm consists of the proteins Ubp8p, Sgf11p, Sus1p, and Sgf73p.	tmpzr1t_l9r_go_relaxed.owl	deubiquitinating module|SAGA DUBm complex|deubiquitination module							mah	2010-09-07T11:19:28Z					cellular_component											owl:Class	
GO:0002169	biolink:NamedThing	3-methylcrotonyl-CoA carboxylase complex, mitochondrial	A mitochondrial protein complex which is capable of 3-methylcrotonyl-CoA carboxylase activity. In mammals, at least, consists as a dodecamer of 6 alpha and 6 beta subunits. MCCC-alpha has a covalently bound biotin essential for the ATP-dependent carboxylation. MCCC-beta possesses carboxyltransferase activity which presumably is essential for binding to 3-methylcrotonyl-CoA.	tmpzr1t_l9r_go_relaxed.owl	mitochondrial MCCC complex|mitochondrial 3-methylcrotonyl-CoA carboxylase holoenzyme|mitochondrial methylcrotonoyl-CoA carboxylase complex							hjd	2010-03-15T04:58:08Z					cellular_component											owl:Class	
GO:1905202	biolink:NamedThing	methylcrotonoyl-CoA carboxylase complex	A protein complex which is capable of methylcrotonoyl-CoA carboxylase activity.	tmpzr1t_l9r_go_relaxed.owl								bf	2016-05-16T11:03:20Z					cellular_component											owl:Class	
GO:0140468	biolink:NamedThing	HRI-mediated signaling	A series of reactions in which a signal is passed on to downstream proteins within the cell via HRI (also known as EIF2AK1), an intracellular protein kinase that is activated by stress signals, such as heme deficiency, oxidative stress, osmotic shock, mitochondrial dysfunction and heat shock.	tmpzr1t_l9r_go_relaxed.owl	EIF2AK1-mediated signaling	https://github.com/geneontology/go-ontology/issues/19153						pg	2020-05-26T08:46:15Z					biological_process											owl:Class	
GO:0140374	biolink:NamedThing	antiviral innate immune response	A defense response against viruses mediated through an innate immune response. An innate immune response is mediated by germline encoded components that directly recognize components of potential pathogens.	tmpzr1t_l9r_go_relaxed.owl								pg	2019-10-10T16:41:12Z					biological_process											owl:Class	
GO:0035686	biolink:NamedThing	sperm fibrous sheath	A cytoskeletal structure surrounding the axoneme and outer dense fibers of the sperm flagellum. Consists of two longitudinal columns connected by closely arrayed semicircular ribs that assemble from distal to proximal throughout spermiogenesis. The fibrous sheath probably influences the degree of flexibility, plane of flagellar motion, and the shape of the flagellar beat.	tmpzr1t_l9r_go_relaxed.owl	flagellum fibrous sheath|flagellar fibrous sheath							bf	2011-02-24T09:10:58Z					cellular_component											owl:Class	
GO:1990974	biolink:NamedThing	actin-dependent nuclear migration	The process whereby the centrosome is held at the cell center while the nucleus moves to the cell rear by actin retrograde flow resulting in the position of the centrosome between the nucleus and the leading edge of the cell.	tmpzr1t_l9r_go_relaxed.owl	actin-dependent nuclear movement							hjd	2016-06-22T19:17:02Z					biological_process											owl:Class	
GO:0035352	biolink:NamedThing	NAD transmembrane transport	The process in which a nicotinamide adenine dinucleotide is transported across a membrane; transport may be of either the oxidized form, NAD, or the reduced form, NADH.	tmpzr1t_l9r_go_relaxed.owl	NAD membrane transport					Note that this term is not intended for use in annotating lateral movement within membranes.		bf	2010-03-04T03:46:20Z					biological_process											owl:Class	
GO:0019398	biolink:NamedThing	gallate catabolic process via gallate dioxygenase activity	The chemical reactions and pathways resulting in the breakdown of gallate, the anion of gallic acid, where the first step is the conversion of gallate to (1E)-4-oxobut-1-ene-1,2,4-tricarboxylate catalyzed by gallate dioxygenase.	tmpzr1t_l9r_go_relaxed.owl	gallate catabolic process via 4-carboxy-2-hydroxhexa-2,3-dienedioate|gallic acid catabolism via 4-carboxy-2-hydroxhexa-2,3-dienedioate|gallate breakdown via 4-carboxy-2-hydroxhexa-2,3-dienedioate|gallate degradation via 4-carboxy-2-hydroxhexa-2,3-dienedioate|gallic acid catabolic process via 4-carboxy-2-hydroxhexa-2,3-dienedioate				MetaCyc:GALLATE-DEGRADATION-II-PWY									biological_process											owl:Class	
GO:1902703	biolink:NamedThing	hexose catabolic process to butan-1-ol	The chemical reactions and pathways resulting in the breakdown of hexose to butan-1-ol.	tmpzr1t_l9r_go_relaxed.owl	hexose catabolic process to butanol|hexose catabolism to butan-1-ol|hexose degradation to butan-1-ol|solventogenesis|hexose catabolic process to 1-butanol|hexose breakdown to butan-1-ol							tb	2014-02-19T18:43:04Z			GO:1990284		biological_process											owl:Class	
GO:0008110	biolink:NamedThing	L-histidine:2-oxoglutarate aminotransferase activity	Catalysis of the reaction: 2-oxoglutarate + L-histidine = 3-(imidazol-5-yl)pyruvate + L-glutamate.	tmpzr1t_l9r_go_relaxed.owl	histidine-2-oxoglutarate aminotransferase activity|histidine transaminase activity|histidine aminotransferase activity				MetaCyc:HISTTRANSAM-RXN|EC:2.6.1.38|KEGG_REACTION:R01161|RHEA:16565									molecular_function											owl:Class	
GO:0019653	biolink:NamedThing	anaerobic purine nucleobase catabolic process	The anaerobic chemical reactions and pathways resulting in the breakdown of purine nucleobases, yielding energy in the form of ATP.	tmpzr1t_l9r_go_relaxed.owl	anaerobic purine catabolic process|anaerobic purine base catabolism|purine fermentation|anaerobic purine base catabolic process|purine base fermentation				MetaCyc:P164-PWY|MetaCyc:PWY-5044|MetaCyc:PWY-5497									biological_process											owl:Class	
GO:0019666	biolink:NamedThing	nitrogenous compound fermentation	The anaerobic chemical reactions and pathways resulting in the breakdown of a nitrogen-containing compound, yielding energy in the form of ATP.	tmpzr1t_l9r_go_relaxed.owl	nitrogenous compound catabolic process													biological_process											owl:Class	
GO:0015660	biolink:NamedThing	formate efflux transmembrane transporter activity	Enables the transfer of formate from the inside of the cell to the outside of the cell across a membrane.	tmpzr1t_l9r_go_relaxed.owl	formate efflux permease activity											GO:0015509		molecular_function											owl:Class	
GO:0031019	biolink:NamedThing	mitochondrial mRNA editing complex	An mRNA editing complex found in the mitochondrion. The best characterized example is that of Trypanosoma brucei, which catalyzes the insertion and deletion of uridylates.	tmpzr1t_l9r_go_relaxed.owl	mitochondrial editosome													cellular_component											owl:Class	
GO:0102712	biolink:NamedThing	gibberellin A13,oxoglutarate:oxygen oxidoreductase activity	Catalysis of the reaction: gibberellin A13 + 2-oxoglutarate + O2 <=> gibberellin A43 + succinate + carbon dioxide.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-6542									molecular_function											owl:Class	
GO:0008884	biolink:NamedThing	glutathionylspermidine amidase activity	Catalysis of the reaction: N1-(gamma-L-glutamyl-L-cysteinyl-glycyl)-spermidine + H2O = gamma-L-glutamyl-L-cysteinyl-glycine + spermidine.	tmpzr1t_l9r_go_relaxed.owl	gamma-L-glutamyl-L-cysteinyl-glycine:spermidine amidase activity|GSP amidase activity|glutathionylspermidine amidohydrolase (spermidine-forming) activity				EC:3.5.1.78|RHEA:17173|MetaCyc:GSPAMID-RXN									molecular_function											owl:Class	
GO:0031218	biolink:NamedThing	arabinogalactan endo-1,4-beta-galactosidase activity	Catalysis of the endohydrolysis of (1->4)-beta-D-galactosidic linkages in arabinogalactans.	tmpzr1t_l9r_go_relaxed.owl	arabinogalactan 4-beta-D-galactanohydrolase activity|arabinogalactanase activity|galactanase activity|endo-1,4-beta-galactanase activity				EC:3.2.1.89|MetaCyc:3.2.1.89-RXN									molecular_function											owl:Class	
GO:0036402	biolink:NamedThing	proteasome-activating activity	Catalysis of the reaction: ATP + H2O = ADP + phosphate, which promotes unfolding of protein substrates, and channel opening of the core proteasome.	tmpzr1t_l9r_go_relaxed.owl	proteasome channel opening activity|proteasome channel gating activity|ATPase involved in positive regulation of proteasomal protein catabolic process|proteasome-activating ATPase activity|proteasomal ATPase activity	https://github.com/geneontology/go-ontology/issues/20879			EC:5.6.1.5			bf	2013-08-12T11:38:20Z					molecular_function											owl:Class	
GO:0052039	biolink:NamedThing	disruption by symbiont of host cytoskeleton	The process in which an organism effects a change that impairs the structure or function of the host cytoskeleton. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	rounding by symbiont of host cells|modification by symbiont of host cytoskeleton											GO:0044054		biological_process											owl:Class	
GO:0140548	biolink:NamedThing	envenomation resulting in blood agglutination in other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with specific proteins binding to cell-surface carbohydrates and causing calcium-dependent agglutination of blood cells in the bitten organism.	tmpzr1t_l9r_go_relaxed.owl	envenomation resulting in erythrocytes agglutination in other organism|envenomation resulting in red blood cells agglutination in other organism	https://github.com/geneontology/go-ontology/issues/18979						pg	2020-11-11T21:42:31Z					biological_process											owl:Class	
GO:0140658	biolink:NamedThing	ATP-dependent chromatin remodeler activity	An activity, driven by ATP hydrolysis, that modulates the contacts between histones and DNA, resulting in a change in chromosome architecture within the nucleosomal array, leading to chromatin remodeling.	tmpzr1t_l9r_go_relaxed.owl	nucleosome-dependent ATPase activity|ATP hydrolysis-dependent chromatin remodeler activity|ATPase-dependent chromatin remodeler activity|nucleosome-activated ATPase activity	https://github.com/geneontology/go-ontology/issues/21786|https://github.com/geneontology/go-ontology/issues/21609|https://github.com/geneontology/go-ontology/issues/6075						pg	2021-06-15T13:57:18Z			GO:0070615		molecular_function											owl:Class	
GO:0052739	biolink:NamedThing	phosphatidylserine 1-acylhydrolase activity	Catalysis of the reaction: phosphatidylserine + H2O = 2-acyl-sn-glycero-3-phosphoserine + fatty acid.	tmpzr1t_l9r_go_relaxed.owl	phosphatidylserine-specific phospholipase A1 activity				EC:3.1.1.32|KEGG_REACTION:R04034|Reactome:R-HSA-8869425									molecular_function											owl:Class	
GO:0018621	biolink:NamedThing	4-sulfobenzoate 3,4-dioxygenase activity	Catalysis of the reaction: 4-sulfobenzoate + H(+) + NADH + O(2) = 3,4-dihydroxybenzoate + NAD(+) + sulfite.	tmpzr1t_l9r_go_relaxed.owl	4-sulfobenzoate 3,4-dioxygenase system|4-sulfobenzoate,NADH:oxygen oxidoreductase (3,4-hydroxylating, sulfite-forming)|4-sulfobenzoate dioxygenase activity|4-sulphobenzoate 3,4-dioxygenase activity				KEGG_REACTION:R01636|RHEA:13937|EC:1.14.12.8|UM-BBD_reactionID:r0293|MetaCyc:4-SULFOBENZOATE-34-DIOXYGENASE-RXN									molecular_function											owl:Class	
GO:0009904	biolink:NamedThing	chloroplast accumulation movement	The relocation process in which chloroplasts in photosynthetic cells move toward a brighter area in a cell to optimize photosynthesis.	tmpzr1t_l9r_go_relaxed.owl	low-fluence-rate response													biological_process											owl:Class	
GO:0097430	biolink:NamedThing	copper ion import across prospore membrane	The directed movement of copper ions from outside of a cell, across an ascospore-type prospore membrane and into the cytosol.	tmpzr1t_l9r_go_relaxed.owl	copper ion transport into forespores|copper ion import into ascospore-type prospore							pr	2012-11-16T12:37:05Z					biological_process											owl:Class	
GO:0017192	biolink:NamedThing	N-terminal peptidyl-glutamine acetylation	The acetylation of a glutamine residue in protein to form the N5-methyl-L-glutamine derivative. The occurrence of this modification has not been confirmed. Its annotation in sequence databases is either due to the misidentification of 2-pyrrolidone-5-carboxylic acid, or to inappropriate homolog comparisons when proteolytic modification is more probable.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0045									biological_process											owl:Class	
GO:0102001	biolink:NamedThing	isoleucine N-monooxygenase (oxime forming) activity	Catalysis of the reaction: L-isoleucine + 2 O2 + 2 NADPH(4-) + 2 H+ <=> (E)-2-methylbutanal oxime + 2 NADP(3-) + carbon dioxide + 3 H2O.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:1.14.13.117-RXN|RHEA:28602|EC:1.14.14.39									molecular_function											owl:Class	
GO:0015971	biolink:NamedThing	guanosine tetraphosphate catabolic process	The chemical reactions and pathways resulting in the breakdown of guanine tetraphosphate (5'-ppGpp-3'), a derivative of guanine riboside with four phosphates.	tmpzr1t_l9r_go_relaxed.owl	guanosine tetraphosphate (5'-ppGpp-3') catabolic process|guanosine tetraphosphate breakdown|guanosine tetraphosphate catabolism|guanosine tetraphosphate degradation|guanosine tetraphosphate (5'-ppGpp-3') catabolism													biological_process											owl:Class	
GO:1902110	biolink:NamedThing	positive regulation of mitochondrial membrane permeability involved in apoptotic process	Any positive regulation of mitochondrial membrane permeability that is involved in apoptotic process.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of transport across mitochondrial membrane involved in apoptotic programmed cell death|positive regulation of mitochondrial membrane permeability involved in apoptotic program|positive regulation of transport across mitochondrial membrane involved in type I programmed cell death|mitochondrial membrane permeability transition involved in programmed cell death by apoptosis|positive regulation of transport across mitochondrial membrane involved in apoptotic process|mitochondrial permeability transition involved in signaling (initiator) caspase activity|positive regulation of transport across mitochondrial membrane involved in signaling (initiator) caspase activity|mitochondrial membrane permeabilization involved in type I programmed cell death|positive regulation of transport across mitochondrial membrane involved in apoptotic program|mitochondrial permeability transition involved in apoptotic cell death|positive regulation of transport across mitochondrial membrane involved in programmed cell death by apoptosis|positive regulation of mitochondrial membrane permeability involved in apoptotic cell death|mitochondrial membrane permeability transition involved in apoptotic cell death|mitochondrial membrane permeabilization involved in apoptosis|mitochondrial membrane permeabilization involved in apoptotic program|positive regulation of mitochondrial membrane permeability involved in type I programmed cell death|mitochondrial membrane permeability transition involved in type I programmed cell death|positive regulation of transport across mitochondrial membrane involved in apoptotic cell death|mitochondrial permeability transition involved in apoptotic process|positive regulation of mitochondrial membrane permeability involved in programmed cell death by apoptosis|mitochondrial permeability transition involved in type I programmed cell death|positive regulation of mitochondrial membrane permeability involved in signaling (initiator) caspase activity|mitochondrial membrane permeabilization involved in apoptotic cell death|mitochondrial membrane permeabilization involved in apoptotic process|mitochondrial membrane permeability transition involved in apoptotic programmed cell death|mitochondrial permeability transition involved in apoptosis|positive regulation of transport across mitochondrial membrane involved in apoptosis|mitochondrial membrane permeabilization involved in signaling (initiator) caspase activity|mitochondrial membrane permeability transition involved in signaling (initiator) caspase activity|mitochondrial membrane permeability transition involved in apoptotic program|mitochondrial membrane permeabilization involved in apoptotic programmed cell death|mitochondrial membrane permeability transition involved in apoptosis|positive regulation of mitochondrial membrane permeability involved in apoptotic programmed cell death|mitochondrial permeability transition involved in apoptotic programmed cell death|mitochondrial permeability transition involved in apoptotic program|mitochondrial permeability transition involved in programmed cell death by apoptosis|mitochondrial membrane permeabilization involved in programmed cell death by apoptosis|positive regulation of mitochondrial membrane permeability involved in apoptosis|mitochondrial membrane permeability transition involved in apoptotic process					Individual components of the mitochondrial permeability transition pore complex, such as the voltage-dependent anion channel (VDAC), the adenine nucleotide translocase (ANT) and cyclophilin-D (CyP-D), are involved in this process.		pr	2013-05-03T12:13:56Z					biological_process											owl:Class	
GO:0036340	biolink:NamedThing	chitin-based cuticle sclerotization by biomineralization	The process of hardening a chitin-based cuticle by mineral incorporation. For example, the cuticle of crustaceans is hardened by the incorporation of calcium carbonate.	tmpzr1t_l9r_go_relaxed.owl	chitin-based cuticle hardening by biomineralisation							bf	2012-09-11T13:50:04Z					biological_process											owl:Class	
GO:0052620	biolink:NamedThing	thymine dehydrogenase activity	Catalysis of the reaction: H2O + thymine + acceptor = 5-methyl-barbiturate + donor-H2.	tmpzr1t_l9r_go_relaxed.owl					EC:1.17.99.4|MetaCyc:RXN-8646|RHEA:13469									molecular_function											owl:Class	
GO:0071925	biolink:NamedThing	thymic stromal lymphopoietin production	The appearance of thymic stromal lymphopoietin (TSLP) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	tmpzr1t_l9r_go_relaxed.owl	TSLP production							mah	2010-09-28T11:38:55Z					biological_process											owl:Class	
GO:0008231	biolink:NamedThing	repressor ecdysone receptor complex	A protein complex consisting of a heterodimer of Ecdysone receptor (EcR) and ultraspiracle (usp) plus an associated corepressor such as SMRTER, which represses transcription of target genes.	tmpzr1t_l9r_go_relaxed.owl	repressor ecdysone receptor holocomplex													cellular_component											owl:Class	
GO:0033979	biolink:NamedThing	box H/ACA RNA metabolic process	The chemical reactions and pathways involving box H/ACA type small nucleolar RNA.	tmpzr1t_l9r_go_relaxed.owl	box H/ACA snoRNA metabolic process|box H/ACA sRNA metabolic process	https://github.com/geneontology/go-ontology/issues/20416												biological_process											owl:Class	
GO:0021623	biolink:NamedThing	oculomotor nerve formation	The process that gives rise to the oculomotor nerve. This process pertains to the initial formation of a structure from unspecified parts. This motor nerve innervates all extraocular muscles except the superior oblique and the lateral rectus muscles. The superior division supplies the levator palpebrae superioris and superior rectus muscles. The inferior division supplies the medial rectus, inferior rectus and inferior oblique muscles. This nerve also innervates the striated muscles of the eyelid. Pupillary constriction and lens movement are mediated by this nerve for near vision. In the orbit the inferior division sends branches that enter the ciliary ganglion where they form functional contacts (synapses) with the ganglion cells. The ganglion cells send nerve fibers into the back of the eye where they travel to ultimately innervate the ciliary muscle and the constrictor pupillae muscle.	tmpzr1t_l9r_go_relaxed.owl	CN III biosynthesis|CN III formation													biological_process											owl:Class	
GO:0006712	biolink:NamedThing	mineralocorticoid catabolic process	The chemical reactions and pathways resulting in the breakdown of mineralocorticoids, hormonal C21 corticosteroids synthesized from cholesterol.	tmpzr1t_l9r_go_relaxed.owl	mineralocorticoid catabolism|mineralocorticoid breakdown|mineralocorticoid degradation													biological_process											owl:Class	
GO:2000940	biolink:NamedThing	negative regulation of plant-type cell wall cellulose catabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of plant-type cell wall cellulose catabolic process.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of plant-type cell wall polysaccharide breakdown							tt	2011-08-01T02:07:17Z					biological_process											owl:Class	
GO:0051685	biolink:NamedThing	maintenance of ER location	Any process in which the endoplasmic reticulum is maintained in a specific location within a cell and prevented from moving elsewhere.	tmpzr1t_l9r_go_relaxed.owl	maintenance of endoplasmic reticulum localization|maintenance of ER localization													biological_process											owl:Class	
GO:0034542	biolink:NamedThing	trimethylarsine oxidase activity	Catalysis of the reaction: trimethylarsine oxide + 2 H+ + 2 e- = trimethylarsine + H2O.	tmpzr1t_l9r_go_relaxed.owl					EC:1.97.1.-|UM-BBD_reactionID:r0807									molecular_function											owl:Class	
GO:0047069	biolink:NamedThing	7,8-dihydroxykynurenate 8,8a-dioxygenase activity	Catalysis of the reaction: 7,8-dihydroxykynurenate + O(2) = 5-(3-carboxylato-3-oxoprop-1-en-1-yl)-4,6-dihydroxypyridine-2-carboxylate + H(+).	tmpzr1t_l9r_go_relaxed.owl	7,8-dihydroxykynurenate oxygenase activity|7,8-dihydroxykynurenate 8,8alpha-dioxygenase activity|7,8-dihydroxykynurenate:oxygen 8,8a-oxidoreductase (decyclizing)|7,8-dihydroxykynurenate:oxygen 8,8alpha-oxidoreductase (decyclizing)				EC:1.13.11.10|MetaCyc:1.13.11.10-RXN|RHEA:23400|KEGG_REACTION:R03253									molecular_function											owl:Class	
GO:1904996	biolink:NamedThing	positive regulation of leukocyte adhesion to vascular endothelial cell	Any process that activates or increases the frequency, rate or extent of leukocyte adhesion to vascular endothelial cell.	tmpzr1t_l9r_go_relaxed.owl	up regulation of leukocyte adhesion to vascular endothelial cell|upregulation of leukocyte adhesion to vascular endothelial cell|activation of leukocyte adhesion to vascular endothelial cell|up-regulation of leukocyte adhesion to vascular endothelial cell							bc	2016-03-01T10:59:22Z					biological_process											owl:Class	
GO:1904566	biolink:NamedThing	cellular response to 1-oleoyl-sn-glycerol 3-phosphate	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 1-oleoyl-sn-glycerol 3-phosphate stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to lysophosphatidic acid|cellular response to LPA|cellular response to 1-oleoyl lysophosphatidic acid|cellular response to oleoyl-L-alpha-lysophosphatidic acid|cellular response to oleoyl lysophosphatidic acid							sl	2015-08-19T15:37:05Z					biological_process											owl:Class	
GO:1990680	biolink:NamedThing	response to melanocyte-stimulating hormone	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a melanocyte-stimulating hormone stimulus. The binding of any one of three melanocyte-stimulating hormones causes dispersal of melanosomes in melanophores of poikilothermic vertebrates.	tmpzr1t_l9r_go_relaxed.owl	response to MSH							sl	2015-03-02T20:49:46Z					biological_process											owl:Class	
GO:0045657	biolink:NamedThing	positive regulation of monocyte differentiation	Any process that activates or increases the frequency, rate or extent of monocyte differentiation.	tmpzr1t_l9r_go_relaxed.owl	upregulation of monocyte differentiation|activation of monocyte differentiation|stimulation of monocyte differentiation|up-regulation of monocyte differentiation|up regulation of monocyte differentiation													biological_process											owl:Class	
GO:0070888	biolink:NamedThing	E-box binding	Binding to an E-box, a DNA motif with the consensus sequence CANNTG that is found in the promoters of a wide array of genes expressed in neurons, muscle and other tissues.	tmpzr1t_l9r_go_relaxed.owl	E-box promoter binding					Note that as agreed during the transcription overhaul, terms specifying binding to specific transcription regulatory motifs are no longer being created. The level of specificity GO has decided to go to is the "core promoter", "core promoter proximal region" and "enhancer". To capture more detail, please consider using column 16.		mah	2009-08-28T10:37:01Z					molecular_function											owl:Class	
GO:1901024	biolink:NamedThing	4-hydroxyphenylacetate biosynthetic process	The chemical reactions and pathways resulting in the formation of 4-hydroxyphenylacetate.	tmpzr1t_l9r_go_relaxed.owl	4-hydroxyphenylacetate formation|4-hydroxyphenylacetate anabolism|4-hydroxyphenylacetate biosynthesis|4-hydroxyphenylacetate synthesis							yaf	2012-06-18T02:32:06Z					biological_process											owl:Class	
GO:0035498	biolink:NamedThing	carnosine metabolic process	The chemical reactions and pathways involving the dipeptide beta-alanyl-L-histidine (carnosine).	tmpzr1t_l9r_go_relaxed.owl	carnosine metabolism							bf	2010-04-29T01:19:52Z					biological_process											owl:Class	
GO:1904536	biolink:NamedThing	regulation of mitotic telomere tethering at nuclear periphery	Any process that modulates the frequency, rate or extent of mitotic telomere tethering at nuclear periphery.	tmpzr1t_l9r_go_relaxed.owl								al	2015-08-04T14:24:26Z					biological_process											owl:Class	
GO:0015313	biolink:NamedThing	fluconazole:proton antiporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + fluconazole(in) = H+(in) + fluconazole(out).	tmpzr1t_l9r_go_relaxed.owl	fluconazole:hydrogen antiporter activity													molecular_function											owl:Class	
GO:0016738	biolink:NamedThing	oxidoreductase activity, acting on reduced flavodoxin as donor, dinitrogen as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which reduced flavodoxin acts as a hydrogen or electron donor and reduces dinitrogen.	tmpzr1t_l9r_go_relaxed.owl					EC:1.19.6.-									molecular_function											owl:Class	
GO:0071882	biolink:NamedThing	phospholipase C-activating adrenergic receptor signaling pathway	The series of molecular signals generated as a consequence of an adrenergic receptor binding to its physiological ligand, where the pathway proceeds with activation of phospholipase C (PLC) and a subsequent release of inositol trisphosphate (IP3) and diacylglycerol (DAG).	tmpzr1t_l9r_go_relaxed.owl	activation of phospholipase C activity by adrenergic receptor signalling pathway|activation of phospholipase C activity by adrenergic receptor signaling pathway|adrenergic receptor, phospholipase C activating pathway							mah	2010-09-13T04:32:03Z					biological_process											owl:Class	
GO:0047473	biolink:NamedThing	D-alanine [D-alanyl carrier protein] ligase activity	Catalysis of the ATP-dependent activation of D-alanine and its transfer as a thiol ester to the phosphopantheinyl prosthetic group of a D-alanyl carrier protein, according to the reaction: ATP + D-alanine + a [D-alaninyl carrier protein] = a D-alanyl-[D-alanyl carrier protein] + AMP + diphosphate.	tmpzr1t_l9r_go_relaxed.owl	D-alanine-D-alanyl carrier protein ligase activity|D-alanine:poly(phosphoribitol) ligase (AMP-forming)|D-alanine-poly(phosphoribitol) ligase activity|D-alanine-activating enzyme activity	https://github.com/geneontology/go-ontology/issues/14237			MetaCyc:6.2.1.M5-RXN|EC:6.2.1.-									molecular_function											owl:Class	
GO:0031235	biolink:NamedThing	intrinsic component of the cytoplasmic side of the plasma membrane	The component of a plasma membrane consisting of gene products and protein complexes that have some covalently attached part (e.g. peptide sequence or GPI anchor) which is embedded in the cytoplasmic side of the plasma membrane only.	tmpzr1t_l9r_go_relaxed.owl	intrinsic to internal side of plasma membrane|intrinsic to internal leaflet of plasma membrane|intrinsic to cytoplasmic side of plasma membrane													cellular_component											owl:Class	
GO:0106340	biolink:NamedThing	tRNA (guanosine 32-2'-O)-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + guanosine 32 in tRNA= S-adenosyl-L-homocysteine + 2'-O-methylguanosine 32 in tRNA.	tmpzr1t_l9r_go_relaxed.owl								hjd	2020-11-05T22:52:49Z					molecular_function											owl:Class	
GO:1901166	biolink:NamedThing	neural crest cell migration involved in autonomic nervous system development	Any neural crest cell migration that is involved in autonomic nervous system development.	tmpzr1t_l9r_go_relaxed.owl								vk	2012-07-19T08:39:56Z					biological_process											owl:Class	
GO:1901961	biolink:NamedThing	isobutanol biosynthetic process	The chemical reactions and pathways resulting in the formation of isobutanol.	tmpzr1t_l9r_go_relaxed.owl	isobutanol anabolism|isobutanol biosynthesis|isobutanol synthesis|isobutanol formation							tt	2013-02-19T21:49:49Z					biological_process											owl:Class	
GO:0019540	biolink:NamedThing	catechol-containing siderophore biosynthetic process	The chemical reactions and pathways resulting in the formation of a siderophore from other compounds, including catechol. Catechol is one of the three major chemical groups incorporated into siderophore structures with hydroxamate and a-hydroxycarboxylate, each having a high selectivity for iron(3+).	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/20975										GO:0031190|GO:0031189		biological_process											owl:Class	
GO:0036324	biolink:NamedThing	vascular endothelial growth factor receptor-2 signaling pathway	Any series of molecular signals initiated by the binding of an extracellular ligand to a vascular endothelial growth factor receptor-2 (VEGFR-2) located on the surface of the receiving cell, and ending with regulation of a downstream cellular process, e.g. transcription.	tmpzr1t_l9r_go_relaxed.owl	FLK-1 signaling pathway|VEGFR-2 signaling pathway|KDR signaling pathway|VEGFR2 signaling pathway							bf	2012-09-04T15:15:40Z					biological_process											owl:Class	
GO:0015654	biolink:NamedThing	tellurite transmembrane transporter activity	Enables the transfer of tellurite from one side of a membrane to the other. Tellurite is a salt of tellurous acid or an oxide of tellurium which occurs sparingly in tufts of white or yellowish crystals.	tmpzr1t_l9r_go_relaxed.owl	tellurite-resistance uptake permease activity|tellurite-resistance uptake transmembrane transporter activity|tellurite uptake transmembrane transporter activity											GO:0015118		molecular_function											owl:Class	
GO:0002263	biolink:NamedThing	cell activation involved in immune response	A change in the morphology or behavior of a cell resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response.	tmpzr1t_l9r_go_relaxed.owl	cell activation during immune response													biological_process											owl:Class	
GO:0009695	biolink:NamedThing	jasmonic acid biosynthetic process	The chemical reactions and pathways resulting in the formation of jasmonic acid, a fatty acid derivative.	tmpzr1t_l9r_go_relaxed.owl	jasmonic acid synthesis|jasmonic acid formation|jasmonic acid anabolism|jasmonic acid biosynthesis				MetaCyc:PWY-735									biological_process											owl:Class	
GO:0018785	biolink:NamedThing	haloacetate dehalogenase activity	Catalysis of the reaction: haloacetate + H2O = glycolate + halide.	tmpzr1t_l9r_go_relaxed.owl	haloacetate halidohydrolase activity|monohaloacetate dehalogenase activity				MetaCyc:HALOACETATE-DEHALOGENASE-RXN|EC:3.8.1.3|RHEA:11044|UM-BBD_enzymeID:e0006									molecular_function											owl:Class	
GO:2000088	biolink:NamedThing	negative regulation of mesonephric glomerulus development	Any process that stops, prevents, or reduces the frequency, rate or extent of mesonephric glomerulus development.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-09-03T06:09:22Z					biological_process											owl:Class	
GO:0102608	biolink:NamedThing	tetracenomycin B3 8-O-methyl transferase activity	Catalysis of the reaction: tetracenomycin B3 + S-adenosyl-L-methionine  <=> tetracenomycin E + S-adenosyl-L-homocysteine  + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-15435									molecular_function											owl:Class	
GO:0098714	biolink:NamedThing	malate import across plasma membrane	The directed movement of malate from outside of a cell, across the plasma membrane and into the cytosol.	tmpzr1t_l9r_go_relaxed.owl	malate import into cell							pr	2012-10-29T11:18:48Z			GO:0097405		biological_process											owl:Class	
GO:0004416	biolink:NamedThing	hydroxyacylglutathione hydrolase activity	Catalysis of the reaction: (S)-(2-hydroxyacyl)glutathione + H2O = glutathione + a 2-hydroxy carboxylate.	tmpzr1t_l9r_go_relaxed.owl	S-2-hydroxylacylglutathione hydrolase activity|acetoacetylglutathione hydrolase activity|S-(2-hydroxyacyl)glutathione hydrolase activity|glyoxalase II activity				Reactome:R-HSA-6783221|RHEA:25245|MetaCyc:GLYOXII-RXN|EC:3.1.2.6									molecular_function											owl:Class	
GO:1903589	biolink:NamedThing	positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis	Any process that activates or increases the frequency, rate or extent of blood vessel endothelial cell proliferation involved in sprouting angiogenesis.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of blood vessel endothelial cell proliferation during sprouting angiogenesis|positive regulation of blood vessel endothelial cell proliferation during sprouting angiogenesis|upregulation of blood vessel endothelial cell proliferation during sprouting angiogenesis|activation of blood vessel endothelial cell proliferation during sprouting angiogenesis|upregulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis|up-regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis|up regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis|up regulation of blood vessel endothelial cell proliferation during sprouting angiogenesis|activation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis							pga	2014-11-04T11:39:47Z					biological_process											owl:Class	
GO:1901693	biolink:NamedThing	negative regulation of compound eye retinal cell apoptotic process	Any process that stops, prevents or reduces the frequency, rate or extent of compound eye retinal cell apoptotic process.	tmpzr1t_l9r_go_relaxed.owl	downregulation of compound eye retinal cell apoptotic process|down-regulation of compound eye retinal cell apoptotic process|inhibition of compound eye retinal cell apoptotic process|down regulation of compound eye retinal cell apoptotic process							pr	2012-12-12T10:28:40Z					biological_process											owl:Class	
GO:0052112	biolink:NamedThing	occlusion by symbiont of host xylem	The process in which an organism reduces the flow of fluid within the host xylem, the tissue in plants that carries water and nutrients up from the roots to the shoot and leaves. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0052110	biolink:NamedThing	occlusion by symbiont of host vascular system	The process in which an organism reduces the flow of fluid within its host's vascular system, the vessels and tissue that carry or circulate fluids, such as blood, lymph or sap, through the body of an animal or plant. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0002194	biolink:NamedThing	hepatocyte cell migration	The orderly movement of a hepatocyte during the development of the liver. Hepatocytes emerge from the hepatic epithelium, populating the septum transversum and lateral mesenchymal areas of the hepatic lobes.	tmpzr1t_l9r_go_relaxed.owl								hjd	2011-08-30T04:27:39Z					biological_process											owl:Class	
GO:0032407	biolink:NamedThing	MutSalpha complex binding	Binding to a MutSalpha mismatch repair complex.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0062055	biolink:NamedThing	photosynthetic state transition	A regulation of the phtosynthetic light reaction in which the light harvesting antenna complexes transition between photosystems.	tmpzr1t_l9r_go_relaxed.owl								dph	2018-07-16T14:00:57Z					biological_process											owl:Class	
GO:1905285	biolink:NamedThing	fibrous ring of heart morphogenesis	The developmental process by which a fibrous ring of heart is generated and organized.	tmpzr1t_l9r_go_relaxed.owl	annulus fibrosus cordis morphogenesis|anulus fibrosus cordis morphogenesis|coronary tendon morphogenesis|anulus fibrosus of heart morphogenesis|Lower's ring morphogenesis|aortic annulus morphogenesis|atrioventricular ring morphogenesis							rl	2016-06-21T09:46:54Z					biological_process											owl:Class	
GO:0016496	biolink:NamedThing	substance P receptor activity	Combining with substance P, the peptide Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met, to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0043760	biolink:NamedThing	acetyldiaminopimelate aminotransferase activity	Catalysis of the reaction: N-acetyl-L-2,6-diaminoheptanedioate + 2-oxoglutarate = N-acetyl-2-L-amino-6-oxoheptanedioate + L-glutamate.	tmpzr1t_l9r_go_relaxed.owl	N-acetyl-diaminopimelate aminotransferase activity|N-acetyl-L,L-diaminopimelate aminotransferase activity													molecular_function											owl:Class	
GO:0019330	biolink:NamedThing	aldoxime metabolic process	The chemical reactions and pathways involving aldoximes, compounds derived by the reaction of an aldose with hydroxylamine, thus containing the aldoxime group -HC=NOH.	tmpzr1t_l9r_go_relaxed.owl	aldoxime metabolism				MetaCyc:P345-PWY									biological_process											owl:Class	
GO:0030759	biolink:NamedThing	methylquercetagetin 6-O-methyltransferase activity	Catalysis of the reaction: 3',4',5,6-tetrahydroxy-3,7-dimethoxyflavone + S-adenosyl-L-methionine(1+) = 3',4',5-trihydroxy-3,6,7-trimethoxyflavone + S-adenosyl-L-homocysteine + H(+).	tmpzr1t_l9r_go_relaxed.owl	S-adenosyl-L-methionine:3',4',5,6-tetrahydroxy-3,7-dimethoxyflavone 6-O-methyltransferase activity|flavonol 6-O-methyltransferase activity|6-OMT|flavonol 6-methyltransferase activity				KEGG_REACTION:R04505|EC:2.1.1.84|MetaCyc:2.1.1.84-RXN|RHEA:18717									molecular_function											owl:Class	
GO:0047502	biolink:NamedThing	(+)-sabinol dehydrogenase activity	Catalysis of the reaction: (+)-cis-sabinol + NAD(+) = (1S,5S)-sabinone + H(+) + NADH.	tmpzr1t_l9r_go_relaxed.owl	(+)-cis-sabinol:NAD+ oxidoreductase activity|(+)-cis-sabinol dehydrogenase activity				MetaCyc:+-SABINOL-DEHYDROGENASE-RXN|RHEA:18329|KEGG_REACTION:R03745|EC:1.1.1.228									molecular_function											owl:Class	
GO:0046276	biolink:NamedThing	methylgallate catabolic process	The chemical reactions and pathways resulting in the breakdown of methylgallate, trihydroxymethylbenzoate, the anion of methylgallic acid.	tmpzr1t_l9r_go_relaxed.owl	methylgallate breakdown|methylgallate degradation|methylgallate catabolism				MetaCyc:METHYLGALLATE-DEGRADATION-PWY									biological_process											owl:Class	
GO:0018412	biolink:NamedThing	protein O-glucuronidation	The modification of a protein by glucuronidation on an amino acid oxygen atom.	tmpzr1t_l9r_go_relaxed.owl	protein amino acid O-glucuronidation													biological_process											owl:Class	
GO:0019515	biolink:NamedThing	lactose catabolic process via UDP-galactose	The chemical reactions and pathways resulting in the breakdown of lactose, via the intermediate UDP-galactose.	tmpzr1t_l9r_go_relaxed.owl	lactose degradation via UDP-galactose|lactose breakdown via UDP-galactose													biological_process											owl:Class	
GO:0035794	biolink:NamedThing	positive regulation of mitochondrial membrane permeability	Any process that increases the frequency, rate or extent of the passage or uptake of molecules by the mitochondrial membrane.	tmpzr1t_l9r_go_relaxed.owl	MPT|mitochondrial permeability transition|mitochondrial membrane permeabilization|mitochondrial membrane permeability transition|positive regulation of transport across mitochondrial membrane							bf	2011-04-11T01:44:06Z					biological_process											owl:Class	
GO:0003109	biolink:NamedThing	positive regulation of the force of heart contraction by circulating norepinephrine	The process in which the secretion of norepinephrine into the bloodstream modulates the force of heart muscle contraction.	tmpzr1t_l9r_go_relaxed.owl	increased force of heart contraction by circulating noradrenaline|increased force of heart contraction by circulating norepinephrine													biological_process											owl:Class	
GO:1904494	biolink:NamedThing	regulation of substance P secretion, neurotransmission	Any process that modulates the frequency, rate or extent of substance P secretion, neurotransmission.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-07-21T19:09:04Z					biological_process											owl:Class	
GO:0080002	biolink:NamedThing	UDP-glucose:4-aminobenzoate acylglucosyltransferase activity	Catalysis of the reaction: 4-aminobenzoate + UDP-glucose = p-aminobenzoate-beta-D-glucopyranosyl ester + UDP.	tmpzr1t_l9r_go_relaxed.owl	UDP-glucose:p-aminobenzoate glucosyltransferase activity|UDP-glucose:p-aminobenzoate acylglucosyltransferase activity|UDP-glucose:pABA acylglucosyltransferase activity				MetaCyc:RXN-6142									molecular_function											owl:Class	
GO:0014820	biolink:NamedThing	tonic smooth muscle contraction	A process in which force is generated within tonic smooth muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. In the tonic smooth muscle, the muscle contraction occurs without an ordered sarcomeric structure. Tonic smooth muscle contraction occurs as a sustained continuous contraction.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0050889	biolink:NamedThing	determination of stimulus intensity	The determination of the perceived strength of a sensory stimulus.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0000025	biolink:NamedThing	maltose catabolic process	The chemical reactions and pathways resulting in the breakdown of the disaccharide maltose (4-O-alpha-D-glucopyranosyl-D-glucopyranose).	tmpzr1t_l9r_go_relaxed.owl	maltose breakdown|maltose degradation|malt sugar catabolism|malt sugar catabolic process|maltose hydrolysis				MetaCyc:MALTOSECAT-PWY									biological_process											owl:Class	
GO:1902131	biolink:NamedThing	(+)-lariciresinol catabolic process	The chemical reactions and pathways resulting in the breakdown of (+)-lariciresinol.	tmpzr1t_l9r_go_relaxed.owl	(+)-lariciresinol catabolism|(+)-lariciresinol breakdown|(+)-lariciresinol degradation							ms	2013-05-21T08:49:54Z					biological_process											owl:Class	
GO:0015863	biolink:NamedThing	xanthosine transport	The directed movement of xanthosine, xanthine riboside, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0033169	biolink:NamedThing	histone H3-K9 demethylation	The modification of histone H3 by the removal of a methyl group from lysine at position 9 of the histone.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0003939	biolink:NamedThing	L-iditol 2-dehydrogenase activity	Catalysis of the reaction: L-iditol + NAD+ = L-sorbose + NADH + H+.	tmpzr1t_l9r_go_relaxed.owl	NAD-sorbitol dehydrogenase|L-iditol:NAD oxidoreductase activity|polyol dehydrogenase activity|sorbitol dehydrogenase activity|glucitol dehydrogenase activity|NAD-dependent sorbitol dehydrogenase activity|L-iditol (sorbitol) dehydrogenase activity|L-iditol:NAD+ 5-oxidoreductase activity|NAD+-dependent sorbitol dehydrogenase activity				EC:1.1.1.14|Reactome:R-HSA-5652195|RHEA:10160|MetaCyc:L-IDITOL-2-DEHYDROGENASE-RXN	Note that enzymes with this activity also act on D-glucitol (giving D-fructose) and other closely related sugar alcohols.								molecular_function											owl:Class	
GO:0036399	biolink:NamedThing	TCR signalosome assembly	The aggregation, arrangement and bonding together of a set of components to form a TCR signalosome.	tmpzr1t_l9r_go_relaxed.owl	LAT signalosome assembly|linker for activation of T cells signalosome assembly							bf	2013-07-18T14:02:53Z					biological_process											owl:Class	
GO:0018721	biolink:NamedThing	trans-9R,10R-dihydrodiolphenanthrene sulfotransferase activity	Catalysis of the reaction: trans-9R,10R-dihydrodiolphenanthrene + 2 X-SO3(-) = 2 HX + phenanthrene-9,10-dihydrodiolsulfate conjugate.	tmpzr1t_l9r_go_relaxed.owl	trans-9R,10R-dihydrodiolphenanthrene sulphotransferase activity				UM-BBD_reactionID:r0559									molecular_function											owl:Class	
GO:0098996	biolink:NamedThing	disruption of host cell glycocalyx during viral entry	The disruption of host cell glycocalyx by viral proteins during virus entry.	tmpzr1t_l9r_go_relaxed.owl	disassembly of glycocalyx during viral entry|catabolism of host glycocalyx during viral entry|degradation of host capsule during virus entry|degradation of host glycocalyx during viral entry				VZ:3938									biological_process											owl:Class	
GO:0019618	biolink:NamedThing	protocatechuate catabolic process, ortho-cleavage	The chemical reactions and pathways resulting in the breakdown of protocatechuate, the anion of 3,4-dihydroxybenzoic acid, to yield beta-ketoadipate.	tmpzr1t_l9r_go_relaxed.owl	protocatechuate catabolic process to beta-ketoadipate|protocatechuate breakdown, ortho-cleavage|protocatechuate degradation, ortho-cleavage|3,4-dihydroxybenzoate catabolic process, ortho-cleavage				MetaCyc:PROTOCATECHUATE-ORTHO-CLEAVAGE-PWY									biological_process											owl:Class	
GO:0047614	biolink:NamedThing	aconitate delta-isomerase activity	Catalysis of the reaction: trans-aconitate = cis-aconitate.	tmpzr1t_l9r_go_relaxed.owl	aconitate delta2-delta3-isomerase activity|aconitate isomerase activity|aconitate D-isomerase activity				EC:5.3.3.7|KEGG_REACTION:R02244|MetaCyc:ACONITATE-DELTA-ISOMERASE-RXN|RHEA:17265									molecular_function											owl:Class	
GO:0036088	biolink:NamedThing	D-serine catabolic process	The chemical reactions and pathways resulting in the breakdown of D-serine, the D-enantiomer of serine, i.e. (2S)-2-amino-3-hydroxypropanoic acid.	tmpzr1t_l9r_go_relaxed.owl	D-serine degradation|D-serine breakdown|D-serine catabolism							bf	2012-01-06T10:58:51Z					biological_process											owl:Class	
GO:0001223	biolink:NamedThing	transcription coactivator binding	Binding to a transcription coactivator, a protein involved in positive regulation of transcription via protein-protein interactions with transcription factors and other proteins that positively regulate transcription. Transcription coactivators do not bind DNA directly, but rather mediate protein-protein interactions between activating transcription factors and the basal transcription machinery.	tmpzr1t_l9r_go_relaxed.owl	RNA polymerase II transcription coactivator binding	https://github.com/geneontology/go-ontology/issues/19354						krc	2012-04-16T03:30:16Z			GO:0001225		molecular_function											owl:Class	
GO:0015670	biolink:NamedThing	carbon dioxide transport	The directed movement of carbon dioxide (CO2) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0035850	biolink:NamedThing	epithelial cell differentiation involved in kidney development	The process in which relatively unspecialized cells acquire specialized structural and/or functional features of an epithelial cell that characterize the cells of the kidney as it progresses from its formation to the mature state.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-05-11T11:34:21Z					biological_process											owl:Class	
GO:0047732	biolink:NamedThing	CDP-abequose epimerase activity	Catalysis of the reaction: CDP-3,6-dideoxy-D-glucose = CDP-3,6-dideoxy-D-mannose.	tmpzr1t_l9r_go_relaxed.owl	cytidine diphosphoparatose epimerase activity|cytidine diphosphoabequose epimerase activity|CDP-tyvelose 2-epimerase activity|cytidine diphosphate paratose-2-epimerase activity|cytidine diphosphodideoxyglucose epimerase activity|CDP-paratose epimerase activity|CDP-D-abequose 2-epimerase activity|CDP-3,6-dideoxy-D-glucose 2-epimerase activity|CDP-paratose 2-epimerase activity				RHEA:21656|EC:5.1.3.10|MetaCyc:RXN-9160|KEGG_REACTION:R04266									molecular_function											owl:Class	
GO:0001540	biolink:NamedThing	amyloid-beta binding	Binding to an amyloid-beta peptide/protein.	tmpzr1t_l9r_go_relaxed.owl	beta-amyloid binding	https://github.com/geneontology/go-ontology/issues/20109												molecular_function											owl:Class	
GO:0015123	biolink:NamedThing	acetate transmembrane transporter activity	Enables the transfer of acetate from one side of a membrane to the other. Acetate is the 2-carbon carboxylic acid ethanoic acid.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0060800	biolink:NamedThing	regulation of cell differentiation involved in embryonic placenta development	Any process that modulates the rate, frequency or extent of cell differentiation that contributes to the progression of the placenta over time, from its initial condition to its mature state.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-08-06T01:20:25Z					biological_process											owl:Class	
GO:0061606	biolink:NamedThing	N-terminal protein amino acid propionylation	The propionylation of the N-terminal amino acid of proteins.	tmpzr1t_l9r_go_relaxed.owl								dph	2014-02-11T14:13:05Z					biological_process											owl:Class	
GO:0140713	biolink:NamedThing	histone chaperone activity	Binding to and carrying a histone or a histone complex until it is deposited on DNA, or degraded.	tmpzr1t_l9r_go_relaxed.owl	histone carrier activity	https://github.com/geneontology/go-ontology/issues/22126						pg	2021-09-10T15:22:31Z					molecular_function											owl:Class	
GO:1903179	biolink:NamedThing	regulation of dopamine biosynthetic process	Any process that modulates the frequency, rate or extent of dopamine biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of dopamine synthesis|regulation of dopamine formation|regulation of dopamine biosynthesis|regulation of dopamine anabolism							bf	2014-07-14T12:17:41Z					biological_process											owl:Class	
GO:0042053	biolink:NamedThing	regulation of dopamine metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving dopamine.	tmpzr1t_l9r_go_relaxed.owl	regulation of dopamine metabolism													biological_process											owl:Class	
GO:0008307	biolink:NamedThing	structural constituent of muscle	The action of a molecule that contributes to the structural integrity of a muscle fiber.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0120133	biolink:NamedThing	negative regulation of actin cortical patch assembly	Any process that stops, prevents, or reduces the frequency, rate or extent of the assembly of actin cortical patches.	tmpzr1t_l9r_go_relaxed.owl	downregulation of actin cortical patch assembly|down regulation of actin cortical patch assembly|down-regulation of actin cortical patch assembly|inhibition of actin cortical patch assembly							krc	2018-02-20T16:23:53Z					biological_process											owl:Class	
GO:0010231	biolink:NamedThing	maintenance of seed dormancy	Any process that maintains a seed in a dormant state.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0097437	biolink:NamedThing	maintenance of dormancy	The dormancy process that results in an organism remaining in dormancy. Dormancy (sometimes called a dormant state) is a suspension of most physiological activity and growth that can be reactivated.	tmpzr1t_l9r_go_relaxed.owl								pr	2012-12-05T15:00:24Z					biological_process											owl:Class	
GO:0008753	biolink:NamedThing	NADPH dehydrogenase (quinone) activity	Catalysis of the reaction: NADPH + H+ + a quinone = NADP+ + a quinol.	tmpzr1t_l9r_go_relaxed.owl	reduced nicotinamide adenine dinucleotide phosphate (quinone) dehydrogenase|NADPH oxidase|NADPH:(quinone-acceptor) oxidoreductase				RHEA:46164|KEGG_REACTION:R07359|EC:1.6.5.10|MetaCyc:NADPH-DEHYDROGENASE-QUINONE-RXN									molecular_function											owl:Class	
GO:0097523	biolink:NamedThing	transcription ternary complex	A protein-DNA-RNA complex composed of RNA polymerase, template DNA, and an RNA transcript.	tmpzr1t_l9r_go_relaxed.owl	transcription protein-DNA-RNA complex							pr	2013-10-18T11:29:57Z					cellular_component											owl:Class	
GO:0001114	biolink:NamedThing	protein-DNA-RNA complex	A macromolecular complex containing protein, DNA, and RNA molecules.	tmpzr1t_l9r_go_relaxed.owl								krc	2010-12-03T02:09:38Z					cellular_component											owl:Class	
GO:0072374	biolink:NamedThing	carotene epsilon hydroxylase activity	Catalysis of the reaction: a carotene + NADPH + O2 + H+ = a beta-ring hydroxylcarotene + NADP+ + H2O. Adds a hydroxyl group to the epsilon ring of the alpha-carotene.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-11-19T03:57:55Z					molecular_function											owl:Class	
GO:0042729	biolink:NamedThing	DASH complex	A large protein complex, containing around 8-10 subunits in yeast, including Duo1p, Dam1p, Dad1p and Ask1p. The complex forms part of the outer kinetochore, associates with microtubules when the kinetochore attaches to the spindle, and plays a role in spindle attachment, chromosome segregation and spindle stability.	tmpzr1t_l9r_go_relaxed.owl	Duo1p-Dam1p-Dad1p complex|Dam1 complex|condensed nuclear chromosome kinetochore-associated DASH complex|DDD complex	https://github.com/geneontology/go-ontology/issues/21126				Note that this complex is conserved in fungi but has not been observed in metazoans.						GO:0043925|GO:0043926		cellular_component											owl:Class	
GO:0007038	biolink:NamedThing	endocytosed protein transport to vacuole	The directed movement of proteins imported into a cell by endocytosis to the vacuole.	tmpzr1t_l9r_go_relaxed.owl	delivery of endocytosed proteins to the vacuole					See also the biological process term 'endocytosis ; GO:0006897'.								biological_process											owl:Class	
GO:0010313	biolink:NamedThing	phytochrome binding	Binding to a phytochrome.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0032795	biolink:NamedThing	heterotrimeric G-protein binding	Binding to a heterotrimeric G-protein.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0043751	biolink:NamedThing	polyphosphate:AMP phosphotransferase activity	Catalysis of the reaction: (polyphosphate)n + AMP = (polyphosphate)n-1 + ADP.	tmpzr1t_l9r_go_relaxed.owl	PAP|PPT													molecular_function											owl:Class	
GO:0019974	biolink:NamedThing	interleukin-14 binding	Binding to interleukin-14.	tmpzr1t_l9r_go_relaxed.owl	IL-14 binding													molecular_function											owl:Class	
GO:1903180	biolink:NamedThing	negative regulation of dopamine biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of dopamine biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of dopamine anabolism|inhibition of dopamine formation|down regulation of dopamine formation|downregulation of dopamine biosynthetic process|down-regulation of dopamine biosynthesis|downregulation of dopamine anabolism|down regulation of dopamine anabolism|negative regulation of dopamine biosynthesis|down regulation of dopamine biosynthetic process|negative regulation of dopamine formation|negative regulation of dopamine anabolism|down regulation of dopamine synthesis|down-regulation of dopamine synthesis|inhibition of dopamine biosynthetic process|down regulation of dopamine biosynthesis|downregulation of dopamine biosynthesis|down-regulation of dopamine biosynthetic process|downregulation of dopamine synthesis|down-regulation of dopamine formation|inhibition of dopamine anabolism|inhibition of dopamine synthesis|downregulation of dopamine formation|inhibition of dopamine biosynthesis|negative regulation of dopamine synthesis							bf	2014-07-14T12:17:47Z					biological_process											owl:Class	
GO:1904646	biolink:NamedThing	cellular response to amyloid-beta	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a amyloid-beta stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to beta-amyloids|cellular response to beta-amyloid							sl	2015-08-31T20:44:49Z					biological_process											owl:Class	
GO:0018177	biolink:NamedThing	protein uridylylation	The addition of phospho-uridine to a protein amino acid.	tmpzr1t_l9r_go_relaxed.owl	protein amino acid uridylylation													biological_process											owl:Class	
GO:0031266	biolink:NamedThing	TRAIL death-inducing signaling complex	A protein complex formed upon binding of TRAIL to its ligand. The complex includes FADD/Mort1 and procaspase-8 addition to the ligand-bound receptor.	tmpzr1t_l9r_go_relaxed.owl	TRAIL death-inducing signalling complex|TRAIL DISC													cellular_component											owl:Class	
GO:0070354	biolink:NamedThing	GATA2-TAL1-TCF3-Lmo2 complex	A protein complex that contains the zinc finger transcription factor GATA2, the LIM domain protein Lmo2 (RBTN2), the basic helix-loop-helix protein TAL1 and its binding partner TCF3. The complex is involved transcriptional regulation in hematopoiesis.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:1904880	biolink:NamedThing	response to hydrogen sulfide	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrogen sulfide stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to sulfane|response to dihydridosulfur							sl	2016-01-04T23:56:27Z					biological_process											owl:Class	
GO:0035505	biolink:NamedThing	positive regulation of myosin light chain kinase activity	Any process that activates or increases the frequency, rate or extent of myosin light chain kinase activity.	tmpzr1t_l9r_go_relaxed.owl								bf	2010-04-30T10:48:09Z					biological_process											owl:Class	
GO:0072390	biolink:NamedThing	phenol metabolic process	The chemical reactions and pathways involving phenol, a compound that consists of a benzene ring with one attached hydroxyl group.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-12-06T04:05:51Z					biological_process											owl:Class	
GO:0001995	biolink:NamedThing	norepinephrine-epinephrine catabolic process in blood stream	The chemical reactions and pathways resulting in the breakdown of norepinephrine or epinephrine in the bloodstream.	tmpzr1t_l9r_go_relaxed.owl	noradrenaline-adrenalin catabolic process in blood stream													biological_process											owl:Class	
GO:0102540	biolink:NamedThing	D-mannose 6-phosphate 1-epimerase activity	Catalysis of the reaction: alpha-D-mannose 6-phosphate = beta-D-mannose 6-phosphate.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-14815									molecular_function											owl:Class	
GO:0003222	biolink:NamedThing	ventricular trabecula myocardium morphogenesis	The process in which the anatomical structures of the trabecular cardiac ventricle muscle are generated and organized.	tmpzr1t_l9r_go_relaxed.owl	trabecula carnea morphogenesis							dph	2009-10-13T10:33:00Z					biological_process											owl:Class	
GO:0050510	biolink:NamedThing	N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity	Catalysis of the reaction: N-acetyl-beta-D-galactosaminyl-(1,4)-beta-D-glucuronosyl-proteoglycan + UDP-alpha-D-glucuronate = beta-D-glucuronosyl-(1,3)-N-acetyl-beta-D-galactosaminyl-(1,4)-beta-D-glucuronosyl-proteoglycan + UDP.	tmpzr1t_l9r_go_relaxed.owl	alpha-D-glucuronate:N-acetyl-beta-D-galactosaminyl-(1->4)-beta-D-glucuronosyl-proteoglycan 3-beta-glucuronosyltransferase activity|N-acetylgalactosaminyl-proteoglycan 3-b-glucuronosyltransferase activity|chondroitin glucuronyltransferase II activity				Reactome:R-HSA-3595178|MetaCyc:2.4.1.226-RXN|Reactome:R-HSA-9632034|Reactome:R-HSA-1971491|EC:2.4.1.226									molecular_function											owl:Class	
GO:0071565	biolink:NamedThing	nBAF complex	A SWI/SNF-type complex that is found in post-mitotic neurons, and in human contains actin and proteins encoded by the ARID1A/BAF250A or ARID1B/BAF250B, SMARCD1/BAF60A, SMARCD3/BAF60C, SMARCA2/BRM/BAF190B, SMARCA4/BRG1/BAF190A, SMARCB1/BAF47, SMARCC1/BAF155, SMARCE1/BAF57, SMARCC2/BAF170, DPF1/BAF45B, DPF3/BAF45C, ACTL6B/BAF53B genes. The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-01-20T03:41:19Z					cellular_component											owl:Class	
GO:0033592	biolink:NamedThing	RNA strand annealing activity	An activity that facilitates the formation of a complementary double-stranded RNA molecule.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/2161												molecular_function											owl:Class	
GO:0030023	biolink:NamedThing	extracellular matrix constituent conferring elasticity	A component of the extracellular matrix that enables the matrix to recoil after transient stretching.	tmpzr1t_l9r_go_relaxed.owl	core extracellular matrix|elastin|core matrisome					Extracellular matrix elastin proteins may be annotated to this term. PMID:27009176, PMID:24443019								molecular_function											owl:Class	
GO:0090704	biolink:NamedThing	nicotinate-O-glucosyltransferase activity	Catalysis of the reaction: nicotinate + UDP-D-glucose = O-D-glucosylnicotinate + UDP.	tmpzr1t_l9r_go_relaxed.owl								tb	2016-09-21T12:46:21Z					molecular_function											owl:Class	
GO:1904975	biolink:NamedThing	response to bleomycin	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bleomycin stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2016-02-18T15:21:23Z					biological_process											owl:Class	
GO:1901012	biolink:NamedThing	(S)-reticuline biosynthetic process	The chemical reactions and pathways resulting in the formation of (S)-reticuline.	tmpzr1t_l9r_go_relaxed.owl	(S)-reticuline biosynthesis|(S)-reticuline anabolism|(S)-reticuline formation|(S)-reticuline synthesis							yaf	2012-06-15T10:46:52Z					biological_process											owl:Class	
GO:0009708	biolink:NamedThing	benzyl isoquinoline alkaloid biosynthetic process	The chemical reactions and pathways resulting in the formation of benzyl isoquinoline alkaloids, compounds with bicyclic N-containing aromatic rings.	tmpzr1t_l9r_go_relaxed.owl	benzyl isoquinoline alkaloid formation|benzyl isoquinoline alkaloid anabolism|benzyl isoquinoline alkaloid biosynthesis|benzyl isoquinoline alkaloid synthesis													biological_process											owl:Class	
GO:0045030	biolink:NamedThing	G protein-coupled UTP receptor activity	Combining with a nucleotide and transmitting the signal to a heterotrimeric G-protein complex to initiate a change in cell activity, activated by UTP.	tmpzr1t_l9r_go_relaxed.owl	uridine nucleotide receptor activity|UTP-activated nucleotide receptor activity|purinoceptor type U											GO:0015065		molecular_function											owl:Class	
GO:0008922	biolink:NamedThing	long-chain fatty acid [acyl-carrier-protein] ligase activity	Catalysis of the reaction: ATP + an acid + [acyl-carrier protein] = AMP + diphosphate + acyl-[acyl-carrier protein]. A long-chain fatty acid is fatty acid with a chain length between C13 and C22.	tmpzr1t_l9r_go_relaxed.owl	acyl-[acyl-carrier-protein] synthetase activity|acyl-acyl-carrier-proteinsynthetase activity|long-chain-fatty-acid-ACP ligase activity|long-chain-fatty-acid:acyl-carrier-protein ligase (AMP-forming) activity|stearoyl-ACP synthetase activity|acyl-acyl carrier protein synthetase|long-chain fatty acid-[acyl-carrier-protein] ligase activity|acyl-ACP synthetase activity|long-chain-fatty-acid-[acyl-carrier protein] ligase activity|long-chain-fatty-acid-[acyl-carrier-protein] ligase activity|acyl-acyl-carrier-protein synthetase activity|long-chain-fatty-acid-acyl-carrier-protein ligase activity				MetaCyc:ACYLACPSYNTH-RXN|EC:6.2.1.20|RHEA:45588|KEGG_REACTION:R07325							GO:0010300		molecular_function											owl:Class	
GO:0055016	biolink:NamedThing	hypochord development	The process whose specific outcome is the progression of the hypochord over time, from its formation to the mature structure. The hypochord is a transient rod-like structure in the embryos of fish, lampreys and amphibians that is located immediately ventral to the notochord. The hypochord may play a role in positioning the dorsal aorta.	tmpzr1t_l9r_go_relaxed.owl	subnotochordal rod development													biological_process											owl:Class	
GO:0032465	biolink:NamedThing	regulation of cytokinesis	Any process that modulates the frequency, rate or extent of the division of the cytoplasm of a cell and its separation into two daughter cells.	tmpzr1t_l9r_go_relaxed.owl	regulation of cell cycle cytokinesis											GO:0071775		biological_process											owl:Class	
GO:0047864	biolink:NamedThing	dimethylaniline-N-oxide aldolase activity	Catalysis of the reaction: N,N-dimethylaniline N-oxide = N-methylaniline + formaldehyde.	tmpzr1t_l9r_go_relaxed.owl	N,N-dimethylaniline-N-oxide formaldehyde-lyase (N-methylaniline-forming)|N,N-dimethylaniline-N-oxide formaldehyde-lyase activity|microsomal N-oxide dealkylase activity|microsomal oxidase II				KEGG_REACTION:R03345|EC:4.1.2.24|RHEA:19321|MetaCyc:DIMETHYLANILINE-N-OXIDE-ALDOLASE-RXN									molecular_function											owl:Class	
GO:0031857	biolink:NamedThing	type 1 parathyroid hormone receptor binding	Binding to a type 1 parathyroid hormone receptor.	tmpzr1t_l9r_go_relaxed.owl	type 1 parathyroid hormone receptor ligand													molecular_function											owl:Class	
GO:0006843	biolink:NamedThing	mitochondrial citrate transmembrane transport	The directed movement of citrate, 2-hydroxy-1,2,3-propanetricarboyxlate, into or out of a mitochondrial matrix.	tmpzr1t_l9r_go_relaxed.owl	mitochondrial citrate transport							vw	2014-11-19T11:08:45Z			GO:1990541		biological_process											owl:Class	
GO:0019894	biolink:NamedThing	kinesin binding	Interacting selectively and non-covalently and stoichiometrically with kinesin, a member of a superfamily of microtubule-based motor proteins that perform force-generating tasks such as organelle transport and chromosome segregation.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0102033	biolink:NamedThing	long-chain fatty acid omega-hydroxylase activity	Catalysis of the reaction: an omega-methyl-long-chain fatty acid + O2 + reduced [NADPH--hemoprotein reductase] = an omega-hydroxy-long-chain fatty acid + H(+) + H2O + oxidized [NADPH--hemoprotein reductase].	tmpzr1t_l9r_go_relaxed.owl	cytochrome P450 fatty acid omega-hydroxylase activity	https://github.com/geneontology/go-ontology/issues/19899|https://github.com/geneontology/go-ontology/issues/14194			MetaCyc:RXN-16394|EC:1.14.14.80|RHEA:56748									molecular_function											owl:Class	
GO:0019112	biolink:NamedThing	phenanthrol glycosyltransferase activity	Catalysis of the reaction: phenanthrol + glucose = phenanthryl-beta-D-glucopyranoside + H2O.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0033465	biolink:NamedThing	cis-zeatin biosynthetic process	The chemical reactions and pathways resulting in the formation of cis-zeatin, (2Z)-2-methyl-4-(9H-purin-6-ylamino)but-2-en-1-ol.	tmpzr1t_l9r_go_relaxed.owl	cis-zeatin formation|cis-zeatin biosynthesis|cis-zeatin synthesis|cis-zeatin anabolism				MetaCyc:PWY-2781									biological_process											owl:Class	
GO:0090432	biolink:NamedThing	myristoyl-CoA ligase activity	Catalysis of the reaction: ATP + myristic acid + CoA = AMP + diphosphate + myristoyl-CoA.	tmpzr1t_l9r_go_relaxed.owl	myristoyl-CoA synthetase activity							tb	2012-07-25T03:31:31Z					molecular_function											owl:Class	
GO:0047068	biolink:NamedThing	N5,N10-methenyltetrahydromethanopterin hydrogenase activity	Catalysis of the reaction: 5,10-methenyl-5,6,7,8-tetrahydromethanopterin + H(2) = 5,10-methylenetetrahydromethanopterin + H(+).	tmpzr1t_l9r_go_relaxed.owl	5,10-methenyltetrahydromethanopterin hydrogenase activity|hydrogen:5,10-methenyltetrahydromethanopterin oxidoreductase activity|hydrogen:N5,N10-methenyltetrahydromethanopterin oxidoreductase activity|H2-forming N5,N10-methylenetetrahydromethanopterin dehydrogenase activity|N5,N10-methylenetetrahydromethanopterin dehydrogenase activity|hydrogen:N(5),N(10)-methenyltetrahydromethanopterin oxidoreductase activity|N(5),N(10)-methenyltetrahydromethanopterin hydrogenase activity|nonmetal hydrogenase activity|H(2)-forming N(5),N(10)-methylenetetrahydromethanopterin dehydrogenase activity|H2-dependent methylene-H4MPT dehydrogenase activity|H(2)-dependent methylene-H(4)MPT dehydrogenase activity				KEGG_REACTION:R04455|RHEA:20017|EC:1.12.98.2|MetaCyc:H2-METHYLENE-THMPT-DEHYDRO-RXN							GO:0016947		molecular_function											owl:Class	
GO:0046995	biolink:NamedThing	oxidoreductase activity, acting on hydrogen as donor, with other known acceptors	Catalysis of an oxidation-reduction (redox) reaction in which hydrogen reduces a known acceptor other than a cytochrome, an iron-sulfur protein, NAD, NADP, or a quinone or similar compound.	tmpzr1t_l9r_go_relaxed.owl					EC:1.12.98.-									molecular_function											owl:Class	
GO:0090683	biolink:NamedThing	GPCR sweet taste receptor activity	A G protein-coupled receptor activity that is responsible for the sense of sweet taste.	tmpzr1t_l9r_go_relaxed.owl	G-protein coupled receptor sweet taste receptor activity							tb	2016-05-20T15:49:18Z					molecular_function											owl:Class	
GO:0021773	biolink:NamedThing	striatal medium spiny neuron differentiation	The process in which a relatively unspecialized cell acquires specialized features of a medium spiny neuron residing in the striatum.	tmpzr1t_l9r_go_relaxed.owl	medium-sized spiny neuron differentiation|striatal MSN differentiation													biological_process											owl:Class	
GO:0018800	biolink:NamedThing	5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase activity	Catalysis of the reaction: 5-oxopent-3-ene-1,2,5-tricarboxylate = 2-oxohept-3-enedioate + CO2.	tmpzr1t_l9r_go_relaxed.owl	HpaG2|OPET decarboxylase activity|5-carboxymethyl-2-oxo-hex-3-ene-1,6-dioate decarboxylase activity|5-carboxymethyl-2-oxo-hex-3-ene-1,7-dioate decarboxylase activity|5-oxopent-3-ene-1,2,5-tricarboxylate carboxy-lyase activity|HpaG-2|5-oxopent-3-ene-1,2,5-tricarboxylate carboxy-lyase (2-oxohept-3-enedioate-forming)				MetaCyc:4.1.1.68-RXN|EC:4.1.1.68|RHEA:14397|UM-BBD_reactionID:r0367									molecular_function											owl:Class	
GO:0038009	biolink:NamedThing	regulation of signal transduction by receptor internalization	Any process that modulates the frequency, rate or extent of signal transduction by the movement of a signaling receptor from the plasma membrane to the inside of the cell. Receptor internalization can have a positive or negative effect on a signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	regulation of signaling pathway by receptor endocytosis							bf	2011-06-23T03:28:47Z					biological_process											owl:Class	
GO:0102665	biolink:NamedThing	indole-3-acetyl-glutamate synthetase activity	Catalysis of the reaction: indole-3-acetate + L-glutamate + ATP <=> H+ + indole-3-acetyl-glutamate + AMP + diphosphoric acid.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-2947									molecular_function											owl:Class	
GO:0070697	biolink:NamedThing	activin receptor binding	Binding to an activin receptor.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-06-04T04:02:13Z					molecular_function											owl:Class	
GO:0050585	biolink:NamedThing	4-hydroxymandelate synthase activity	Catalysis of the reaction: 4-hydroxyphenylpyruvate + O2 = 4-hydroxymandelate + CO2.	tmpzr1t_l9r_go_relaxed.owl	4-hydroxyphenylpyruvate:oxygen oxidoreductase (decarboxylating)|4-hydroxyphenylpyruvate dioxygenase II activity				RHEA:21376|EC:1.13.11.46|MetaCyc:1.13.11.46-RXN									molecular_function											owl:Class	
GO:0030685	biolink:NamedThing	nucleolar preribosome	Any complex of pre-rRNAs, ribosomal proteins, and associated proteins formed in the nucleolus during ribosome biogenesis.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:1902706	biolink:NamedThing	hexose catabolic process to acetate	The chemical reactions and pathways resulting in the breakdown of hexose to acetate.	tmpzr1t_l9r_go_relaxed.owl	hexose breakdown to acetate|hexose catabolism to acetate|acidogenesis|hexose degradation to acetate							tb	2014-02-19T18:43:23Z			GO:1990286		biological_process											owl:Class	
GO:0070989	biolink:NamedThing	oxidative demethylation	The process of removing one or more methyl groups from a molecule, involving the oxidation (i.e. electron loss) of one or more atoms in the substrate.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-10-29T03:33:25Z					biological_process											owl:Class	
GO:0009018	biolink:NamedThing	sucrose phosphorylase activity	Catalysis of the reaction: sucrose + phosphate = D-fructose + alpha-D-glucose 1-phosphate.	tmpzr1t_l9r_go_relaxed.owl	sucrose glucosyltransferase activity|disaccharide glucosyltransferase activity|sucrose:phosphate alpha-D-glucosyltransferase activity				RHEA:24048|EC:2.4.1.7|MetaCyc:SUCROSE-PHOSPHORYLASE-RXN									molecular_function											owl:Class	
GO:0000732	biolink:NamedThing	strand displacement	The rejection of the broken 3' single-strand DNA molecule that formed heteroduplex DNA with its complement in an intact duplex DNA. The Watson-Crick base pairing in the original duplex is restored. The rejected 3' single-strand DNA molecule reanneals with its original complement to reform two intact duplex molecules.	tmpzr1t_l9r_go_relaxed.owl	displacement loop processing|D-loop processing|displacement loop dissociation|D-loop dissociation													biological_process											owl:Class	
GO:0003252	biolink:NamedThing	negative regulation of cell proliferation involved in heart valve morphogenesis	Any process that decreases the rate, frequency or extent of cell proliferation that contributes to the shaping of a heart valve.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-10-13T02:10:39Z					biological_process											owl:Class	
GO:0003250	biolink:NamedThing	regulation of cell proliferation involved in heart valve morphogenesis	Any process that modulates the rate, frequency or extent of cell proliferation that contributes to the shaping of a heart valve.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-10-13T02:03:42Z					biological_process											owl:Class	
GO:0032266	biolink:NamedThing	phosphatidylinositol-3-phosphate binding	Binding to phosphatidylinositol-3-phosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 3' position.	tmpzr1t_l9r_go_relaxed.owl	PtdIns-3-P binding|phosphatidylinositol 3-phosphate binding													molecular_function											owl:Class	
GO:0002315	biolink:NamedThing	marginal zone B cell differentiation	The process in which a B cell in the spleen acquires the specialized features of a marginal zone B cell. Marginal zone B cells are localized in a distinct anatomical region of the spleen that represents the major antigen-filtering and scavenging area (by specialized macrophages resident there). It appears that they are preselected to express a BCR repertoire similar to B-1 B cells, biased toward bacterial cell wall constituents and senescent self-components (such as oxidized LDL).	tmpzr1t_l9r_go_relaxed.owl	marginal zone B-lymphocyte differentiation|marginal zone B lymphocyte differentiation|marginal zone B-cell differentiation|marginal zone B cell development					Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.								biological_process											owl:Class	
GO:0050247	biolink:NamedThing	raucaffricine beta-glucosidase activity	Catalysis of the reaction: H(2)O + raucaffricine = D-glucose + vomilenine.	tmpzr1t_l9r_go_relaxed.owl	raucaffricine b-glucosidase activity|raucaffricine beta-D-glucosidase activity|raucaffricine beta-D-glucohydrolase activity|raucaffricine glucosidase activity				MetaCyc:RAUCAFFRICINE-BETA-GLUCOSIDASE-RXN|KEGG_REACTION:R03703|RHEA:14557|EC:3.2.1.125									molecular_function											owl:Class	
GO:0002338	biolink:NamedThing	B-1b B cell differentiation	The process in which B cells acquire the specialized features of B-1b B cells. B-1b B cells are B-1 cells that do not express CD5.	tmpzr1t_l9r_go_relaxed.owl	B-1b B cell development|B-1b B-cell differentiation|B-1b B lymphocyte differentiation|B-1b B-lymphocyte differentiation					Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.								biological_process											owl:Class	
GO:0033626	biolink:NamedThing	positive regulation of integrin activation by cell surface receptor linked signal transduction	Any series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell that lead to the increased affinity of an integrin, a heterodimeric adhesion receptor formed by the non-covalent association of particular alpha and beta subunits, for its extracellular ligands.	tmpzr1t_l9r_go_relaxed.owl	cell surface receptor linked signal transduction leading to integrin complex activation|cell surface receptor linked signal transduction leading to integrin activation													biological_process											owl:Class	
GO:0103047	biolink:NamedThing	methyl beta-D-glucoside 6-phosphate glucohydrolase activity	Catalysis of the reaction: methyl beta-D-glucoside 6-phosphate + H2O = beta-D-glucose 6-phosphate + methanol.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN0-6994|EC:3.2.1.86									molecular_function											owl:Class	
GO:0046948	biolink:NamedThing	hydroxylysine catabolic process	The chemical reactions and pathways resulting in the breakdown of hydroxylysine (5-hydroxy-2,6-diaminohexanoic acid), a chiral alpha-amino acid.	tmpzr1t_l9r_go_relaxed.owl	hydroxylysine catabolism|hydroxylysine degradation|hydroxylysine breakdown													biological_process											owl:Class	
GO:0006551	biolink:NamedThing	leucine metabolic process	The chemical reactions and pathways involving leucine, 2-amino-4-methylpentanoic acid.	tmpzr1t_l9r_go_relaxed.owl	leucine metabolism													biological_process											owl:Class	
GO:0043508	biolink:NamedThing	negative regulation of JUN kinase activity	Any process that stops, prevents, or reduces the frequency, rate or extent of JUN kinase activity.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of JNK activity|down regulation of JNK activity|negative regulation of JUNK activity|downregulation of JNK activity|inhibition of JNK activity													biological_process											owl:Class	
GO:0046329	biolink:NamedThing	negative regulation of JNK cascade	Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the JNK cascade.	tmpzr1t_l9r_go_relaxed.owl	inhibition of JNK cascade|downregulation of JNK cascade|down regulation of JNK cascade|down-regulation of JNK cascade													biological_process											owl:Class	
GO:1903865	biolink:NamedThing	sigma factor antagonist complex	A protein complex which is capable of sigma factor antagonist activity.	tmpzr1t_l9r_go_relaxed.owl								bhm	2015-02-04T15:39:34Z					cellular_component											owl:Class	
GO:0032348	biolink:NamedThing	negative regulation of aldosterone biosynthetic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of aldosterone.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of aldosterone biosynthetic process|downregulation of aldosterone biosynthetic process|inhibition of aldosterone biosynthetic process|down regulation of aldosterone biosynthetic process													biological_process											owl:Class	
GO:0099585	biolink:NamedThing	release of sequestered calcium ion into presynaptic cytosol	The process in which calcium ions sequestered in the endoplasmic reticulum, Golgi apparatus or mitochondria are released into the presynaptic cytosol.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0019399	biolink:NamedThing	cyclohexanol oxidation	The cyclohexanol metabolic process in which cyclohexanol is converted to adipate.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:CYCLOHEXANOL-OXIDATION-PWY									biological_process											owl:Class	
GO:0034553	biolink:NamedThing	mitochondrial respiratory chain complex II assembly	The aggregation, arrangement and bonding together of a set of components to form respiratory chain complex II, in the mitochondrial inner membrane.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0035135	biolink:NamedThing	post-embryonic anal fin morphogenesis	The process, occurring after embryonic development, by which the anatomical structures of the anal fin are generated and organized. An anal fin is an unpaired medial fin on the ventral aspect near the caudal end of a fish, which provides lateral stability while swimming.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0102529	biolink:NamedThing	apigenin 7-O-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine  + apigenin-7-olate <=> S-adenosyl-L-homocysteine  + genkwanin.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-14661									molecular_function											owl:Class	
GO:0080099	biolink:NamedThing	L-methionine:2-oxoglutarate aminotransferase activity	Catalysis of the reaction: L-methionine + 2-oxoglutarate = 4-methylthio-2-oxobutyrate + L-glutamate.	tmpzr1t_l9r_go_relaxed.owl	L-methionine:alpha-ketoglutarate aminotransferase activity					This reaction falls within the larger set of reactions associated with EC:2.6.1.5 (See BRENDA: http://www.brenda-enzymes.org/php/result_flat.php4?ecno=2.6.1.5).		dhl	2009-04-23T03:51:20Z					molecular_function											owl:Class	
GO:0034856	biolink:NamedThing	2-hydroxyhexa-2,4-dienoate hydratase activity	Catalysis of the reaction: (2E,4E)-2-hydroxyhexa-2,4-dienoate + H2O = 4-hydroxy-2-oxohexanoate.	tmpzr1t_l9r_go_relaxed.owl					EC:4.2.1.132|UM-BBD_reactionID:r1281|RHEA:32535									molecular_function											owl:Class	
GO:0046387	biolink:NamedThing	deoxyribose 1,5-bisphosphate metabolic process	The chemical reactions and pathways involving deoxyribose 1,5-bisphosphate, the diphosphorylated sugar 1,5-diphospho-2-deoxyribose.	tmpzr1t_l9r_go_relaxed.owl	deoxyribose 1,5-bisphosphate metabolism													biological_process											owl:Class	
GO:0031956	biolink:NamedThing	medium-chain fatty acid-CoA ligase activity	Catalysis of the reaction: ATP + a medium-chain carboxylic acid + CoA = AMP + diphosphate + an acyl-CoA; a medium-chain fatty acid is any fatty acid with a chain length of between C6 and C12.	tmpzr1t_l9r_go_relaxed.owl	medium-chain fatty-acid-CoA ligase activity|medium-chain fatty acid activation|medium-chain-fatty-acid-CoA ligase activity	https://github.com/geneontology/go-ontology/issues/18967			RHEA:48340|EC:6.2.1.2									molecular_function											owl:Class	
GO:0019611	biolink:NamedThing	4-toluenecarboxylate metabolic process	The chemical reactions and pathways involving 4-toluenecarboxylate, 4-methylbenzenecarboxylate, the anion of carboxylic acid attached to a methylbenzene molecule.	tmpzr1t_l9r_go_relaxed.owl	4-toluenecarboxylate metabolism|p-toluate metabolism|p-toluate metabolic process													biological_process											owl:Class	
GO:0080120	biolink:NamedThing	CAAX-box protein maturation	A series of specific posttranslational modifications to the CAAX box region of CAAX box proteins. CAAX box proteins are eukaryotic proteins that contain a CAAX motif where the C is a cysteine, the two A residues are aliphatic amino acids and the X can be one of several amino acids. The CAAX-box proteins undergo three sequential, enzymatic, post-translational modifications essential to their targeting: First, the proteins are prenylated by one of two prenyltransferases called farnesyltransferase and geranylgeranyltransferase-I. Prenylation results in the covalent attachment of either farnesyl or geranylgeranyl isoprenoid groups to the cysteine in the CAAX box motif. Prenylation is followed by proteolytic removal of the last three amino acids of the protein (AAX). Finally, the newly exposed carboxylate group of the isoprenylcysteine is methylated by an ER-associated prenyl-dependent carboxylmethyltransferase.	tmpzr1t_l9r_go_relaxed.owl	farnesylated protein maturation|CAAX-box protein processing							dhl	2009-04-28T03:06:13Z					biological_process											owl:Class	
GO:0015824	biolink:NamedThing	proline transport	The directed movement of proline, pyrrolidine-2-carboxylic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	L-proline transport													biological_process											owl:Class	
GO:0060748	biolink:NamedThing	tertiary branching involved in mammary gland duct morphogenesis	The branching process in which the mammary gland ducts form tertiary branches off of the secondary branches as part of diestrus and pregnancy.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-06-22T10:44:51Z					biological_process											owl:Class	
GO:0018662	biolink:NamedThing	phenol 2-monooxygenase activity	Catalysis of the reaction: phenol + NADPH + H+ + O2 = catechol + NADP+ + H2O.	tmpzr1t_l9r_go_relaxed.owl	phenol,NADPH:oxygen oxidoreductase (2-hydroxylating)|phenol hydroxylase activity|phenol o-hydroxylase activity				EC:1.14.13.7|UM-BBD_enzymeID:e0208|MetaCyc:PHENOL-2-MONOOXYGENASE-RXN|RHEA:17061									molecular_function											owl:Class	
GO:0018188	biolink:NamedThing	peptidyl-proline di-hydroxylation	The modification of peptidyl-proline to form trans-2,3-cis-3,4-dihydroxy-L-proline.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0282									biological_process											owl:Class	
GO:0045183	biolink:NamedThing	translation factor activity, non-nucleic acid binding	A translation regulator activity that does not involve binding to nucleic acids.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0090125	biolink:NamedThing	cell-cell adhesion involved in synapse maturation	The attachment of the pre-synaptic cell to the post-synaptic cell via adhesion molecules that contributes to synapse maturation.	tmpzr1t_l9r_go_relaxed.owl	trans-synaptic adhesion							tb	2009-12-07T02:43:24Z					biological_process											owl:Class	
GO:2001240	biolink:NamedThing	negative regulation of extrinsic apoptotic signaling pathway in absence of ligand	Any process that stops, prevents or reduces the frequency, rate or extent of extrinsic apoptotic signaling pathway in absence of ligand.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of dependence receptor signaling pathway|negative regulation of extrinsic apoptotic signalling pathway in absence of ligand|negative regulation of extrinsic apoptosis in absence of ligand							pr	2011-11-24T01:33:25Z					biological_process											owl:Class	
GO:0036196	biolink:NamedThing	zymosterol metabolic process	The chemical reactions and pathways involving zymosterol, (5alpha-cholesta-8,24-dien-3beta-ol).	tmpzr1t_l9r_go_relaxed.owl								bf	2012-04-20T10:27:06Z					biological_process											owl:Class	
GO:0009930	biolink:NamedThing	longitudinal side of cell surface	The side of the cell parallel to the zygotic axis.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0032683	biolink:NamedThing	negative regulation of connective tissue growth factor production	Any process that stops, prevents, or reduces the frequency, rate, or extent of connective tissue growth factor production.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of IGFBP8 production|downregulation of connective tissue growth factor production|negative regulation of hypertrophic chondrocyte-specific gene product 24 production|negative regulation of Hcs24 production|down-regulation of connective tissue growth factor production|down regulation of connective tissue growth factor production|inhibition of connective tissue growth factor production|negative regulation of CTGF production|negative regulation of Fisp12 production|negative regulation of connective tissue growth factor biosynthetic process|negative regulation of CCN2 production											GO:0045421		biological_process											owl:Class	
GO:0002668	biolink:NamedThing	negative regulation of T cell anergy	Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell anergy.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of T-lymphocyte anergy|negative regulation of T-cell anergy|negative regulation of T lymphocyte anergy|inhibition of T cell anergy|down-regulation of T cell anergy|down regulation of T cell anergy|downregulation of T cell anergy													biological_process											owl:Class	
GO:0042049	biolink:NamedThing	cellular acyl-CoA homeostasis	Any process involved in the maintenance of an internal steady state of acyl-CoA within a cell or between a cell and its external environment.	tmpzr1t_l9r_go_relaxed.owl	cell acyl-CoA homeostasis													biological_process											owl:Class	
GO:1901551	biolink:NamedThing	negative regulation of endothelial cell development	Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell development.	tmpzr1t_l9r_go_relaxed.owl	downregulation of endothelial cell development|down regulation of endothelial cell development|down-regulation of endothelial cell development|inhibition of endothelial cell development							pr	2012-10-30T12:59:54Z					biological_process											owl:Class	
GO:1902336	biolink:NamedThing	positive regulation of retinal ganglion cell axon guidance	Any process that activates or increases the frequency, rate or extent of retinal ganglion cell axon guidance.	tmpzr1t_l9r_go_relaxed.owl	upregulation of retinal ganglion cell axon guidance|positive regulation of retinal ganglion cell axon pathfinding|upregulation of retinal ganglion cell axon pathfinding|up-regulation of retinal ganglion cell axon guidance|activation of retinal ganglion cell axon guidance|activation of retinal ganglion cell axon pathfinding|up regulation of retinal ganglion cell axon pathfinding|up-regulation of retinal ganglion cell axon pathfinding|up regulation of retinal ganglion cell axon guidance							rl	2013-07-29T13:02:25Z					biological_process											owl:Class	
GO:0030536	biolink:NamedThing	larval feeding behavior	Feeding behavior in a larval (immature) organism.	tmpzr1t_l9r_go_relaxed.owl	larval feeding behaviour					See also the biological process term 'feeding behavior ; GO:0007631'.								biological_process											owl:Class	
GO:0043220	biolink:NamedThing	Schmidt-Lanterman incisure	Regions within compact myelin in which the cytoplasmic faces of the enveloping myelin sheath are not tightly juxtaposed, and include cytoplasm from the cell responsible for making the myelin. Schmidt-Lanterman incisures occur in the compact myelin internode, while lateral loops are analogous structures found in the paranodal region adjacent to the nodes of Ranvier.	tmpzr1t_l9r_go_relaxed.owl	Schmidt-Lanterman cleft				NIF_Subcellular:sao254777664							GO:0044287		cellular_component											owl:Class	
GO:0042654	biolink:NamedThing	ecdysis-triggering hormone receptor activity	Combining with ecdysis-triggering hormone to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	ecdysis-triggering hormone binding|ETH receptor													molecular_function											owl:Class	
GO:0106275	biolink:NamedThing	NADP+-protein-arginine ADP-ribosyltransferase activity	Catalysis of the reaction: NADP+ + L-arginine = nicotinamide + N2-(ADP-D-ribosyl)-L-arginine.	tmpzr1t_l9r_go_relaxed.owl					EC:2.4.2.31|RHEA:54884			hjd	2020-07-02T01:39:04Z					molecular_function											owl:Class	
GO:0050692	biolink:NamedThing	DNA binding domain binding	Binding to a protein's DNA binding domain (DBD).	tmpzr1t_l9r_go_relaxed.owl	DBD binding													molecular_function											owl:Class	
GO:0034203	biolink:NamedThing	glycolipid translocation	The translocation, or flipping, of glycolipid molecules from one monolayer of a membrane bilayer to the opposite monolayer.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0048371	biolink:NamedThing	lateral mesodermal cell differentiation	The process in which a relatively unspecialized cell acquires the specialized features of a lateral mesoderm cell.	tmpzr1t_l9r_go_relaxed.owl	lateral mesoderm cell differentiation|lateral plate mesoderm cell differentiation|lateral plate mesodermal cell differentiation													biological_process											owl:Class	
GO:0003831	biolink:NamedThing	beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity	Catalysis of the reaction: UDP-galactose + N-acetyl-beta-D-glucosaminylglycopeptide = UDP + beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminylglycopeptide.	tmpzr1t_l9r_go_relaxed.owl	glycoprotein 4-beta-galactosyltransferase activity|glycoprotein 4-beta-galactosyl-transferase activity|GalT activity|beta-N-acetyl-beta-(1,4)-galactosyltransferase activity|UDP-galactose:N-acetyl-beta-D-glucosaminylglycopeptide beta-1,4-galactosyltransferase activity|uridine diphosphogalactose-glycoprotein galactosyltransferase activity|UDPgalactose-glycoprotein galactosyltransferase activity|thyroid glycoprotein beta-galactosyltransferase|beta-N-acetyl-beta-1,4-galactosyltransferase activity|glycoprotein beta-galactosyltransferase activity|UDP-galactose--glycoprotein galactosyltransferase activity|UDPgalactose:N-acetyl-beta-D-glucosaminylglycopeptide beta-1,4-galactosyltransferase activity|thyroid galactosyltransferase activity				Reactome:R-HSA-9035949|Reactome:R-HSA-3656230|Reactome:R-HSA-2046298|Reactome:R-HSA-2025723|RHEA:22932|Reactome:R-HSA-975919|Reactome:R-HSA-9035950|Reactome:R-HSA-1912352|EC:2.4.1.38|MetaCyc:2.4.1.38-RXN|Reactome:R-HSA-4793956|Reactome:R-HSA-2046265									molecular_function											owl:Class	
GO:0004088	biolink:NamedThing	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity	Catalysis of the reaction: 2 ATP + L-glutamine + CO2 + H2O = 2 ADP + phosphate + glutamate + carbamoyl phosphate.	tmpzr1t_l9r_go_relaxed.owl	carbamoyl-phosphate synthetase (glutamine-hydrolyzing) activity|glutamine-dependent carbamoyl-phosphate synthase activity|hydrogen-carbonate:L-glutamine amido-ligase (ADP-forming, carbamate-phosphorylating) activity|CPS activity|carbamoyl phosphate synthetase activity|GD-CPSase activity|carbamyl phosphate synthetase (glutamine) activity|carbamoyl phosphate synthase (glutamine-hydrolyzing) activity|glutamine-dependent carbamyl phosphate synthetase activity|carbamoyl-phosphate synthetase (glutamine-hydrolysing) activity|carbamoylphosphate synthetase II activity|carbamoyl-phosphate synthase (glutamine-hydrolysing) activity|carbon-dioxide::L-glutamine amido-ligase (ADP-forming, carbamate-phosphorylating) activity				EC:6.3.5.5|Reactome:R-HSA-73577|MetaCyc:CARBPSYN-RXN|RHEA:18633									molecular_function											owl:Class	
GO:1904828	biolink:NamedThing	positive regulation of hydrogen sulfide biosynthetic process	Any process that activates or increases the frequency, rate or extent of hydrogen sulfide biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	activation of hydrogen sulphide biosynthesis|upregulation of hydrogen sulfide biosynthesis|up-regulation of hydrogen sulphide biosynthesis|upregulation of hydrogen sulfide anabolism|activation of hydrogen sulfide anabolism|up-regulation of hydrogen sulfide biosynthesis|positive regulation of hydrogen sulfide formation|up regulation of hydrogen sulfide formation|up regulation of hydrogen sulfide biosynthesis|up regulation of hydrogen sulphide biosynthetic process|upregulation of hydrogen sulfide biosynthetic process|up regulation of hydrogen sulfide synthesis|positive regulation of hydrogen sulphide biosynthesis|activation of hydrogen sulfide biosynthesis|up-regulation of hydrogen sulfide synthesis|upregulation of hydrogen sulfide formation|activation of hydrogen sulfide biosynthetic process|activation of hydrogen sulfide synthesis|positive regulation of hydrogen sulfide biosynthesis|up regulation of hydrogen sulfide anabolism|up regulation of hydrogen sulphide biosynthesis|activation of hydrogen sulphide biosynthetic process|up regulation of hydrogen sulfide biosynthetic process|upregulation of hydrogen sulphide biosynthesis|activation of hydrogen sulfide formation|up-regulation of hydrogen sulphide biosynthetic process|upregulation of hydrogen sulfide synthesis|positive regulation of hydrogen sulfide synthesis|up-regulation of hydrogen sulfide biosynthetic process|up-regulation of hydrogen sulfide formation|positive regulation of hydrogen sulfide anabolism|up-regulation of hydrogen sulfide anabolism|upregulation of hydrogen sulphide biosynthetic process|positive regulation of hydrogen sulphide biosynthetic process							rph	2015-11-24T10:15:41Z					biological_process											owl:Class	
GO:0043180	biolink:NamedThing	rhythmic inhibition	Any process involved in the generation of rhythmic, synchronous inhibitory synaptic inputs in a neural circuit.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0046574	biolink:NamedThing	glycuronidase activity	Catalysis of the hydrolysis of glucuronosides, yielding free glucuronic acid.	tmpzr1t_l9r_go_relaxed.owl	glucuronyl hydrolase activity													molecular_function											owl:Class	
GO:0018041	biolink:NamedThing	C-terminal peptidyl-glycine amidation	The formation of a C-terminal peptidyl-glycine acid amide by hydrolysis and oxidation of an interior Gly-Gly peptide in a secreted protein.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0088									biological_process											owl:Class	
GO:0044629	biolink:NamedThing	negative regulation of complement activation, classical pathway in other organism	Any process that stops, prevents, or reduces the frequency, rate or extent of complement activation by the classical pathway, in a different organism.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-07-05T01:03:25Z					biological_process											owl:Class	
GO:0034572	biolink:NamedThing	monodemethylisoproturon dimethylaminedehydrogenase activity	Catalysis of the reaction: monodemethylisoproturon + H2O = didemethylisoproturon + formaldehyde + 2 H+ + 2 e-.	tmpzr1t_l9r_go_relaxed.owl					EC:1.5.99.-|UM-BBD_reactionID:r0897									molecular_function											owl:Class	
GO:0001830	biolink:NamedThing	trophectodermal cell fate commitment	The cell fate commitment of precursor cells that will become trophectoderm cells.	tmpzr1t_l9r_go_relaxed.owl	trophectoderm cell fate commitment					See also the Anatomical Dictionary for Mouse Development ontology terms 'TS4, trophectoderm ; EMAP:19'.								biological_process											owl:Class	
GO:0032120	biolink:NamedThing	ascospore-type prospore membrane formation	The process in which the nascent membrane forms at the meiotic outer plaque and grows until closure occurs and forespores, or prospores, are formed.	tmpzr1t_l9r_go_relaxed.owl	ascospore-type prospore membrane assembly|FSM assembly|prospore membrane biogenesis|forespore membrane biosynthesis|FSM formation|FSM biosynthesis|forespore membrane formation	https://github.com/geneontology/go-ontology/issues/14712										GO:0099097		biological_process											owl:Class	
GO:0045604	biolink:NamedThing	regulation of epidermal cell differentiation	Any process that modulates the frequency, rate or extent of epidermal cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	regulation of hypodermal cell differentiation													biological_process											owl:Class	
GO:0001533	biolink:NamedThing	cornified envelope	A type of plasma membrane that has been modified through addition of distinct intracellular and extracellular components, including ceramide, found in cornifying epithelial cells (corneocytes).	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0071093	biolink:NamedThing	alpha5-beta1 integrin-fibronectin-tissue transglutaminase complex	A protein complex that consists of an alpha5-beta1 integrin complex bound to fibronectin and tissue transglutaminase.	tmpzr1t_l9r_go_relaxed.owl	ITGA5-ITGB1-FN1-TGM2 complex							mah	2009-11-06T04:47:22Z					cellular_component											owl:Class	
GO:0102055	biolink:NamedThing	12-hydroxyjasmonate sulfotransferase activity	Catalysis of the reaction: 3'-phosphonato-5'-adenylyl sulfate + a 12-hydroxyjasmonate <=> adenosine 3',5'-bismonophosphate + a 12-hydroxyjasmonate sulfate.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-10451|EC:2.8.2.39|RHEA:52728									molecular_function											owl:Class	
GO:0015016	biolink:NamedThing	[heparan sulfate]-glucosamine N-sulfotransferase activity	Catalysis of the reaction: 3'-phosphoadenylyl sulfate + [heparan sulfate]-glucosamine = adenosine 3',5'-bisphosphate + [heparan sulfate]-N-sulfoglucosamine.	tmpzr1t_l9r_go_relaxed.owl	heparitin sulfotransferase activity|N-heparan sulfate sulfotransferase activity|desulfoheparin sulfotransferase activity|heparan sulfate N-sulfotransferase activity|N-desulfoheparin sulfotransferase activity|3'-phosphoadenylyl-sulfate:[heparan sulfate]-glucosamine N-sulfotransferase activity|heparin-glucosamine N-sulfotransferase activity|3'-phosphoadenylylsulfate:N-desulfoheparin sulfotransferase activity|heparitin N-sulfotransferase activity|glucosaminyl N-deacetylase/N-sulfotransferase activity|3'-phosphoadenylyl-sulfate:N-desulfoheparin N-sulfotransferase activity|3'-phosphoadenylyl-sulfate:heparitin N-sulfotransferase activity|heparan sulfate 2-N-sulfotransferase activity|heparin N-sulfotransferase activity|heparitin N-sulphotransferase activity|heparan sulfate N-deacetylase/N-sulfotransferase activity|PAPS:DSH sulfotransferase activity|heparin N-deacetylase/N-sulfotransferase activity|N-HSST activity|PAPS:N-desulfoheparin sulfotransferase activity|[heparan sulphate]-glucosamine N-sulphotransferase activity|heparin N-deacetylase/N-sulphotransferase activity				EC:2.8.2.8|RHEA:21980|Reactome:R-HSA-2022860|MetaCyc:HEPARITIN-SULFOTRANSFERASE-RXN	Note that this activity includes EC:2.8.2.12 (deleted from EC).						GO:0051910|GO:0015022|GO:0004393		molecular_function											owl:Class	
GO:0009011	biolink:NamedThing	starch synthase activity	Catalysis of the reaction: ADP-glucose + (1,4)-alpha-D-glucosyl(n) = ADP + (1,4)-alpha-D-glucosyl(n+1).	tmpzr1t_l9r_go_relaxed.owl	ADP-glucose transglucosylase activity|glycogen synthase activity|ADPG-starch glucosyltransferase activity|adenosine diphosphate glucose-starch glucosyltransferase activity|ADP-glucose:1,4-alpha-D-glucan 4-alpha-D-glucosyltransferase activity|starch synthetase activity|ADP-glucose--starch glucosyltransferase activity|ADPglucose-starch glucosyltransferase activity|adenosine diphosphoglucose-starch glucosyltransferase activity|starch (bacterial glycogen) synthase activity|ADPglucose:1,4-alpha-D-glucan 4-alpha-D-glucosyltransferase activity|ADP-glucose starch synthase activity|ADPG starch synthetase activity				MetaCyc:GLYCOGENSYN-RXN|EC:2.4.1.21									molecular_function											owl:Class	
GO:0050255	biolink:NamedThing	ribitol 2-dehydrogenase activity	Catalysis of the reaction: D-ribitol + NAD(+) = D-ribulose + H(+) + NADH.	tmpzr1t_l9r_go_relaxed.owl	ribitol:NAD+ 2-oxidoreductase activity|ribitol dehydrogenase B (mutant enzyme with different properties)|ribitol dehydrogenase A (wild type)|adonitol dehydrogenase activity|ribitol dehydrogenase D (mutant enzyme with different properties)				RHEA:20053|KEGG_REACTION:R01895|EC:1.1.1.56|MetaCyc:RIBITOL-2-DEHYDROGENASE-RXN									molecular_function											owl:Class	
GO:1990481	biolink:NamedThing	mRNA pseudouridine synthesis	The intramolecular conversion of uridine to pseudouridine in an mRNA molecule.	tmpzr1t_l9r_go_relaxed.owl	mRNA pseudouridylation							mcc	2014-09-12T15:13:39Z					biological_process											owl:Class	
GO:0016596	biolink:NamedThing	thienylcyclohexylpiperidine binding	Binding to thienylcyclohexylpiperidine.	tmpzr1t_l9r_go_relaxed.owl	TCP binding													molecular_function											owl:Class	
GO:0015902	biolink:NamedThing	carbonyl cyanide m-chlorophenylhydrazone transport	The directed movement of carbonyl cyanide m-chlorophenylhydrazone into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Carbonyl cyanide m-chlorophenylhydrazone is a proton ionophore, commonly used as an uncoupling agent and inhibitor of photosynthesis because of its effects on mitochondrial and chloroplast membranes.	tmpzr1t_l9r_go_relaxed.owl	CCCP transport													biological_process											owl:Class	
GO:0033878	biolink:NamedThing	hormone-sensitive lipase activity	Catalysis of the reactions: diacylglycerol + H2O = monoacylglycerol + a carboxylate; triacylglycerol + H2O = diacylglycerol + a carboxylate; and monoacylglycerol + H2O = glycerol + a carboxylate.	tmpzr1t_l9r_go_relaxed.owl	diacylglycerol acylhydrolase activity|HSL				MetaCyc:STEROL-ESTERASE-RXN|EC:3.1.1.79|MetaCyc:TRIACYLGLYCEROL-LIPASE-RXN									molecular_function											owl:Class	
GO:0033588	biolink:NamedThing	elongator holoenzyme complex	A heterohexameric protein complex composed two discrete heterotrimeric subcomplexes that is involved in modification of wobble nucleosides in tRNA.	tmpzr1t_l9r_go_relaxed.owl	Elongator core complex	https://github.com/geneontology/go-ontology/issues/22076				Despite its name, this complex is not directly involved in transcriptional elongation (PMID:23165209).						GO:0033589		cellular_component											owl:Class	
GO:1903943	biolink:NamedThing	regulation of hepatocyte apoptotic process	Any process that modulates the frequency, rate or extent of hepatocyte apoptotic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of hepatocyte apoptosis							sl	2015-02-19T12:54:40Z					biological_process											owl:Class	
GO:1905829	biolink:NamedThing	negative regulation of prostaglandin catabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of prostaglandin catabolic process.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of prostaglandin catabolism|down-regulation of prostaglandin breakdown|downregulation of prostaglandin degradation|inhibition of prostaglandin catabolism|down regulation of prostaglandin catabolic process|inhibition of prostaglandin breakdown|inhibition of prostaglandin degradation|inhibition of prostaglandin catabolic process|down regulation of prostaglandin degradation|downregulation of prostaglandin catabolic process|down regulation of prostaglandin catabolism|down-regulation of prostaglandin catabolism|down regulation of prostaglandin breakdown|downregulation of prostaglandin breakdown|negative regulation of prostaglandin degradation|down-regulation of prostaglandin degradation|downregulation of prostaglandin catabolism|down-regulation of prostaglandin catabolic process|negative regulation of prostaglandin breakdown							sl	2017-01-16T21:36:48Z					biological_process											owl:Class	
GO:0019387	biolink:NamedThing	methanogenesis, from methanol	The formation of methane, a colorless, odorless, flammable gas with the formula CH4, from other components, including methanol.	tmpzr1t_l9r_go_relaxed.owl	methane biosynthetic process from methanol|methane biosynthesis from methanol				MetaCyc:METHFORM-PWY									biological_process											owl:Class	
GO:0075135	biolink:NamedThing	suppression by symbiont of host calcium or calmodulin-mediated signal transduction	Any process in which the symbiont organism stops, prevents, or reduces the frequency, rate or extent of calcium or calmodulin-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	negative regulation by symbiont of host calcium or calmodulin-mediated signal transduction|negative regulation by symbiont of host Ca++ or calmodulin-mediated signal transduction					Note that this term is used to annotate gene products of the symbiont. To annotate host gene products, consider the biological process term "Negative regulation by host of symbiont calcium or calmodulin-mediated signal transduction ; GO:0075105".								biological_process											owl:Class	
GO:0075133	biolink:NamedThing	modulation by symbiont of host calcium or calmodulin-mediated signal transduction	Any process in which the symbiont modulates the frequency, rate or extent of calcium or calmodulin-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	modulation by symbiont of host Ca++ or calmodulin-mediated signal transduction					Note that this term is used to annotate gene products of the symbiont. To annotate host gene products, consider the biological process term "modulation by host of symbiont calcium or calmodulin-mediated signal transduction ; GO:0075103".								biological_process											owl:Class	
GO:0048710	biolink:NamedThing	regulation of astrocyte differentiation	Any process that modulates the frequency, rate or extent of astrocyte differentiation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0047119	biolink:NamedThing	2-methyl-branched-chain-enoyl-CoA reductase activity	Catalysis of the reaction: 2-methylbutanoyl-CoA + NAD(+) = 2-methylbut-2-enoyl-CoA + H(+) + NADH.	tmpzr1t_l9r_go_relaxed.owl	2-methyl-branched-chain-acyl-CoA:NAD+ 2-oxidoreductase activity				MetaCyc:1.3.1.52-RXN|EC:1.3.8.5|KEGG_REACTION:R03169|RHEA:43780									molecular_function											owl:Class	
GO:0072710	biolink:NamedThing	response to hydroxyurea	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydroxyurea stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to HU							mah	2012-04-11T04:15:42Z					biological_process											owl:Class	
GO:0046505	biolink:NamedThing	sulfolipid metabolic process	The chemical reactions and pathways involving sulfolipids, any compound containing a sulfonic acid residue joined by a carbon-sulfur bond to a lipid.	tmpzr1t_l9r_go_relaxed.owl	sulfolipid metabolism|sulpholipid metabolism|sulpholipid metabolic process													biological_process											owl:Class	
GO:0008541	biolink:NamedThing	proteasome regulatory particle, lid subcomplex	The subcomplex of the proteasome regulatory particle that forms the peripheral lid, which is added on top of the base subcomplex.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0018673	biolink:NamedThing	anthraniloyl-CoA monooxygenase activity	Catalysis of the reaction: 2-aminobenzoyl-CoA + 2 NADPH + 2 H+ + O2 = 2-amino-5-oxocyclohex-1-enecarboxyl-CoA + H2O + 2 NADP+.	tmpzr1t_l9r_go_relaxed.owl	2-aminobenzoyl-CoA,NAD(P)H:oxygen oxidoreductase (de-aromatizing)|2-aminobenzoyl-CoA monooxygenase/reductase activity|anthraniloyl coenzyme A reductase activity				EC:1.14.13.40|UM-BBD_reactionID:r0568|MetaCyc:ANTHRANILOYL-COA-MONOOXYGENASE-RXN									molecular_function											owl:Class	
GO:0015753	biolink:NamedThing	D-xylose transmembrane transport	The process in which D-xylose is transported across a lipid bilayer, from one side of a membrane to the other. D-xylose (the naturally occurring enantiomer is always D-) is a constituent of plant polysaccharides.	tmpzr1t_l9r_go_relaxed.owl	D-xylose transport													biological_process											owl:Class	
GO:0048078	biolink:NamedThing	positive regulation of compound eye pigmentation	Any process that activates or increases the frequency, rate or extent of establishment of a pattern of pigment in the compound eye.	tmpzr1t_l9r_go_relaxed.owl	stimulation of eye pigmentation|upregulation of eye pigmentation|positive regulation of eye pigmentation|activation of eye pigmentation|up-regulation of eye pigmentation|up regulation of eye pigmentation													biological_process											owl:Class	
GO:0043907	biolink:NamedThing	Cys-tRNA(Pro) hydrolase activity	Catalysis of the hydrolysis of misacylated Cys-tRNA(Pro).	tmpzr1t_l9r_go_relaxed.owl	Cys-tRNA(Pro) deacetylase activity|Cys-tRNAPro hydrolase activity				EC:3.1.1.-									molecular_function											owl:Class	
GO:1990534	biolink:NamedThing	thermospermine oxidase activity	Catalysis of the reaction: S-methyl-5'-thioadenosine + thermospermine + H+ = S-adenosyl 3-(methylthio)propylamine + spermidine.	tmpzr1t_l9r_go_relaxed.owl								tb	2014-11-13T00:41:59Z					molecular_function											owl:Class	
GO:0046328	biolink:NamedThing	regulation of JNK cascade	Any process that modulates the frequency, rate or extent of signal transduction mediated by the JNK cascade.	tmpzr1t_l9r_go_relaxed.owl	regulation of SAPK cascade													biological_process											owl:Class	
GO:0021530	biolink:NamedThing	spinal cord oligodendrocyte cell fate specification	The process in which a cell becomes capable of differentiating autonomously into an oligodendrocyte in an environment that is neutral with respect to the developmental pathway.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0036190	biolink:NamedThing	indole-2-monooxygenase activity	Catalysis of the reaction: indole + NAD(P)H + H+ + O2 = indolin-2-one + NAD(P)+ + H2O.	tmpzr1t_l9r_go_relaxed.owl					KEGG_REACTION:R07403|RHEA:31899|EC:1.14.14.153			bf	2012-04-19T11:24:48Z					molecular_function											owl:Class	
GO:0071499	biolink:NamedThing	cellular response to laminar fluid shear stress	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a laminar fluid shear stress stimulus. Laminar fluid flow is the force acting on an object in a system where the fluid is moving across a solid surface in parallel layers.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-12-18T02:43:02Z					biological_process											owl:Class	
GO:0034616	biolink:NamedThing	response to laminar fluid shear stress	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a laminar fluid shear stress stimulus. Laminar fluid flow is the force acting on an object in a system where the fluid is moving across a solid surface in parallel layers. As an example, laminar shear stress can be seen where blood flows against the luminal side of blood vessel walls.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0090121	biolink:NamedThing	low-density lipoprotein particle disassembly involved in cholesterol transport	The disassembly into constituent parts of the low-density lipoprotein particle in the lysosome that contributes to cholesterol transport.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-12-07T12:59:14Z					biological_process											owl:Class	
GO:0061712	biolink:NamedThing	tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase	Catalysis of the reaction: N(6)-L-threonylcarbamoyladenine(37) in tRNA + sulfur-(sulfur carrier) + 2 S-adenosyl-L-methionine = 2-methylthio-N(6)-L-threonylcarbamoyladenine(37) in tRNA + S-adenosyl-L-homocysteine + (sulfur carrier) + L-methionine + 5'-deoxyadenosine.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-14531|RHEA:37075|EC:2.8.4.5			dph	2015-06-23T08:47:10Z					molecular_function											owl:Class	
GO:0140573	biolink:NamedThing	histone H3-containing nucleosome	A complex comprised of DNA wound around a multisubunit core and associated proteins containing the histone H3, which forms the primary packing unit of DNA into higher order structures.	tmpzr1t_l9r_go_relaxed.owl	histone H3 containing nucleosome	https://github.com/geneontology/go-ontology/issues/20585						pg	2021-01-04T16:22:43Z					cellular_component											owl:Class	
GO:0038197	biolink:NamedThing	type I interferon receptor complex	A heterodimeric protein complex that binds a type I interferon and transmits the signal across the membrane into the cell. Consists of an alpha subunit (IFNAR1) and a beta subunit (IFNAR2).	tmpzr1t_l9r_go_relaxed.owl	interferon-alpha/beta receptor complex							bf	2013-11-27T14:53:50Z					cellular_component											owl:Class	
GO:0070450	biolink:NamedThing	interleukin4-interleukin-4 receptor complex	A protein complex that is formed by the association of a heterodimeric interleukin-4 receptor complex with an interleukin-4 molecule.	tmpzr1t_l9r_go_relaxed.owl	IL4-IL4 receptor complex|IL4-IL4R-IL2RG complex													cellular_component											owl:Class	
GO:0036275	biolink:NamedThing	response to 5-fluorouracil	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 5-fluorouracil stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to 5-fluoropyrimidine-2,4(1H,3H)-dione|response to fluorouracil					Note that this term is in the subset of terms that should not be used for direct manual annotation of gene products. It was created to be used for cross-referencing by other ontologies. Direct annotations to this term may be amended during annotation QC.		bf	2012-07-09T02:08:23Z					biological_process											owl:Class	
GO:0033435	biolink:NamedThing	AUA codon-amino acid adaptor activity	A triplet codon-amino acid adaptor activity that recognizes an AUA codon.	tmpzr1t_l9r_go_relaxed.owl	ATA codon-amino acid adaptor activity|isoleucine tRNA					Note that in the standard genetic code, ATA codes for isoleucine.								molecular_function											owl:Class	
GO:0140227	biolink:NamedThing	serotonin-gated cation-selective signaling pathway	A series of molecular signals initiated by serotonin binding to a seratonin receptor on the surface of the target cell, followed by the movement of ions through a channel in the receptor complex. Ends with regulation of a downstream cellular process, e.g. transcription.	tmpzr1t_l9r_go_relaxed.owl	5-HT-gated cation-selective signalling pathway|5-HT-gated cation-selective signaling pathway|5-hydroxytryptamine-gated cation-selective signalling pathway|5-hydroxytryptamine-gated cation-selective signaling pathway|serotonin-gated cation-selective signalling pathway							pg	2018-06-02T13:34:51Z					biological_process											owl:Class	
GO:0106362	biolink:NamedThing	protein-arginine N-acetylglucosaminyltransferase activity	Catalysis of the reaction: L-arginyl-[protein] + UDP-N-acetyl-alpha-D-glucosamine = H(+) + N(omega)-(N-acetyl-beta-D-glucosaminyl)-L-arginyl-[protein] + UDP.	tmpzr1t_l9r_go_relaxed.owl					RHEA:66632			hjd	2021-02-05T15:42:52Z					molecular_function											owl:Class	
GO:1901827	biolink:NamedThing	zeaxanthin biosynthetic process	The chemical reactions and pathways resulting in the formation of zeaxanthin.	tmpzr1t_l9r_go_relaxed.owl	zeaxanthin biosynthesis|zeaxanthin formation|zeaxanthin anabolism|zeaxanthin synthesis							yaf	2013-01-22T11:37:07Z					biological_process											owl:Class	
GO:0044653	biolink:NamedThing	dextrin alpha-glucosidase activity	Catalysis of the reaction: dextrin + H2O = alpha-D-glucose.	tmpzr1t_l9r_go_relaxed.owl					EC:3.2.1.-			jl	2012-07-23T02:01:12Z					molecular_function											owl:Class	
GO:0034978	biolink:NamedThing	PDX1-PBX1b-MRG1 complex	A protein complex that contains the homeodomain proteins PDX1, PBX1b and MRG1 (MEIS2) and is involved in the transcriptional regulation of pancreatic acinar cell-specific genes.	tmpzr1t_l9r_go_relaxed.owl	acinar cell-specific C complex													cellular_component											owl:Class	
GO:0010086	biolink:NamedThing	embryonic root morphogenesis	The process in which the anatomical structures of the embryonic root are generated and organized.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1902170	biolink:NamedThing	cellular response to reactive nitrogen species	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reactive nitrogen species stimulus.	tmpzr1t_l9r_go_relaxed.owl								tb	2013-05-23T00:23:59Z			GO:1990106		biological_process											owl:Class	
GO:1904855	biolink:NamedThing	proteasome regulatory particle binding	Binding to a proteasome regulatory particle.	tmpzr1t_l9r_go_relaxed.owl	PA700-dependent proteasome activator binding|modulator complex binding|19S regulatory particle binding|PA700 proteasome activator binding							mah	2015-12-15T11:54:27Z					molecular_function											owl:Class	
GO:0071503	biolink:NamedThing	response to heparin	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heparin stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-12-18T03:33:49Z					biological_process											owl:Class	
GO:0043559	biolink:NamedThing	insulin binding	Binding to insulin, a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0016254	biolink:NamedThing	preassembly of GPI anchor in ER membrane	The stepwise addition of the components of the GPI anchor on to phosphatidylinositol lipids in the endoplasmic reticulum membrane.	tmpzr1t_l9r_go_relaxed.owl	preassembly of GPI anchor in endoplasmic reticulum membrane													biological_process											owl:Class	
GO:1903191	biolink:NamedThing	glyoxal biosynthetic process	The chemical reactions and pathways resulting in the formation of glyoxal.	tmpzr1t_l9r_go_relaxed.owl	glyoxal biosynthesis|glyoxal formation|glyoxal synthesis|glyoxal anabolism							bf	2014-07-15T10:11:57Z					biological_process											owl:Class	
GO:0008906	biolink:NamedThing	inosine kinase activity	Catalysis of the reaction: ATP + inosine = ADP + IMP.	tmpzr1t_l9r_go_relaxed.owl	inosine-guanosine kinase activity|ATP:inosine 5'-phosphotransferase activity|inosine kinase (phosphorylating)				RHEA:21140|EC:2.7.1.73|MetaCyc:INOSINEKIN-RXN									molecular_function											owl:Class	
GO:0050842	biolink:NamedThing	copper incorporation via L-cysteinyl copper sulfido molybdopterin cytosine dinucleotide	The incorporation of copper into a protein by L-cysteinyl copper sulfido molybdopterin cytosine dinucleotide.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0355									biological_process											owl:Class	
GO:0051584	biolink:NamedThing	regulation of dopamine uptake involved in synaptic transmission	Any process that modulates the frequency, rate or extent of the directed movement of the catecholamine neurotransmitter dopamine into a cell.	tmpzr1t_l9r_go_relaxed.owl	regulation of dopamine import involved in synaptic transmission													biological_process											owl:Class	
GO:1901104	biolink:NamedThing	tetracenomycin C metabolic process	The chemical reactions and pathways involving tetracenomycin C.	tmpzr1t_l9r_go_relaxed.owl	tetracenomycin C metabolism							yaf	2012-07-11T02:50:32Z					biological_process											owl:Class	
GO:0019121	biolink:NamedThing	peptidoglycan-protein cross-linking via N6-mureinyl-L-lysine	The process of linking a protein to peptidoglycan via the epsilon amino group of lysine to the diaminopimelic acid of the peptidoglycan.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0218									biological_process											owl:Class	
GO:2000842	biolink:NamedThing	positive regulation of dehydroepiandrosterone secretion	Any process that activates or increases the frequency, rate or extent of dehydroepiandrosterone secretion.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of DHEA secretion|positive regulation of dehydroisoandrosterone secretion|positive regulation of 3beta-hydroxyandrost-5-en-17-one secretion							bf	2011-07-26T08:41:36Z					biological_process											owl:Class	
GO:0097111	biolink:NamedThing	endoplasmic reticulum-Golgi intermediate compartment organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endoplasmic reticulum (ER)-Golgi intermediate compartment.	tmpzr1t_l9r_go_relaxed.owl	endoplasmic reticulum-Golgi intermediate compartment organisation|endoplasmic reticulum-Golgi intermediate compartment organization and biogenesis|ERGIC organization|ER-Golgi intermediate compartment organization							pr	2011-07-29T04:45:54Z					biological_process											owl:Class	
GO:0004999	biolink:NamedThing	vasoactive intestinal polypeptide receptor activity	Combining with vasoactive intestinal polypeptide to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0015042	biolink:NamedThing	trypanothione-disulfide reductase activity	Catalysis of the reaction: NADP+ + trypanothione = NADPH + H+ + trypanothione disulfide.	tmpzr1t_l9r_go_relaxed.owl	NADPH:trypanothione oxidoreductase activity|N1,N8-bis(glutathionyl)spermidine reductase activity|N(1),N(8)-bis(glutathionyl)spermidine reductase activity|trypanothione:NADP+ oxidoreductase activity|trypanothione-disulphide reductase activity|trypanothione reductase activity				MetaCyc:1.8.1.12-RXN|EC:1.8.1.12|RHEA:16757	Note that this function was formerly EC:1.6.4.8.								molecular_function											owl:Class	
GO:1990603	biolink:NamedThing	dark adaptation	The process by which the rods of the retina gradually become fully responsive to dim light when no longer exposed to bright light.	tmpzr1t_l9r_go_relaxed.owl						The proteins RGS9-1 and Gb5L localize to the rod inner segment during dark adaptation, but to the rod outer segment during light adaptation. PMID:23555598		hjd	2015-01-09T20:35:46Z					biological_process											owl:Class	
GO:1901170	biolink:NamedThing	naphthalene catabolic process	The chemical reactions and pathways resulting in the breakdown of naphthalene.	tmpzr1t_l9r_go_relaxed.owl	naphthalene breakdown|naphthalene degradation|naphthalene metabolic process|naphthalene catabolism|naphthalene metabolism	https://github.com/geneontology/go-ontology/issues/20974			UM-BBD_pathwayID:naph			yaf	2012-07-19T09:33:50Z			GO:0018931		biological_process											owl:Class	
GO:0072485	biolink:NamedThing	response to spindle assembly checkpoint signaling	A process that occurs in response to signals generated as a result of spindle assembly checkpoint signaling.	tmpzr1t_l9r_go_relaxed.owl	response to signal involved in spindle assembly checkpoint|spindle assembly checkpoint effector process							mah	2010-12-09T12:19:35Z					biological_process											owl:Class	
GO:0101026	biolink:NamedThing	mitotic nuclear membrane biogenesis	A process in which the nuclear inner or outer membrane is synthesized, aggregates, and bonds together during mitotic nuclear division.	tmpzr1t_l9r_go_relaxed.owl	nuclear membrane biogenesis involved in mitotic nuclear division													biological_process											owl:Class	
GO:0110012	biolink:NamedThing	protein localization to P-body	Any process in which a protein is transported to, or maintained at, a P-body.	tmpzr1t_l9r_go_relaxed.owl	protein localisation to P-body|protein localization to cytoplasmic mRNA processing body|protein localization to P body							kmv	2017-05-03T14:04:51Z					biological_process											owl:Class	
GO:0015798	biolink:NamedThing	myo-inositol transport	The directed movement of myo-inositol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Myo-inositol is 1,2,3,4,5/4,6-cyclohexanehexol, a growth factor for animals and microorganisms.	tmpzr1t_l9r_go_relaxed.owl	vitamin Bh transport													biological_process											owl:Class	
GO:0061609	biolink:NamedThing	fructose-1-phosphate aldolase activity	Catalysis of the reaction: D-fructose-1-phosphate = dihydroxyacetone phosphate + D-glyceraldehyde.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-5656438|Reactome:R-HSA-70342|RHEA:30851			dph	2014-03-28T08:54:24Z					molecular_function											owl:Class	
GO:0102919	biolink:NamedThing	5,6-dimethylbenzimidazole synthase activity	Catalysis of the reaction: FMNH2 + O2 <=> 5,6-dimethylbenzimidazole + D-erythrose 4-phosphate + dialuric acid.	tmpzr1t_l9r_go_relaxed.owl					RHEA:27345|EC:1.13.11.79|MetaCyc:RXN-8771									molecular_function											owl:Class	
GO:0140472	biolink:NamedThing	cell cortex of non-growing cell tip	The region directly beneath the plasma membrane at the cell tip at which no growth takes place.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/17249						pg	2020-06-18T13:33:58Z					cellular_component											owl:Class	
GO:0090572	biolink:NamedThing	RNA polymerase III transcription repressor complex	A protein complex, located in the nucleus, that possesses activity that prevents or downregulates transcription from a RNA polymerase III promoter.	tmpzr1t_l9r_go_relaxed.owl								tb	2014-05-09T13:26:16Z					cellular_component											owl:Class	
GO:0071246	biolink:NamedThing	cellular response to chlorate	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chlorate stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-12-03T02:45:36Z					biological_process											owl:Class	
GO:0047046	biolink:NamedThing	homoisocitrate dehydrogenase activity	Catalysis of the reaction: NAD+ + 3-carboxy-2-hydroxyadipate = NADH + H+ + CO2 + 2-keto-adipate.	tmpzr1t_l9r_go_relaxed.owl	(1R,2S)-1-hydroxybutane-1,2,4-tricarboxylate:NAD+ oxidoreductase (decarboxylating)|homoisocitric dehydrogenase activity|3-carboxy-2-hydroxyadipate:NAD+ oxidoreductase (decarboxylating)|2-hydroxy-3-carboxyadipate dehydrogenase activity|3-carboxy-2-hydroxyadipate:NAD(+) oxidoreductase (decarboxylating) activity|(-)-1-hydroxy-1,2,4-butanetricarboxylate:NAD+ oxidoreductase (decarboxylating)|3-carboxy-2-hydroxyadipate dehydrogenase activity|(-)-1-hydroxy-1,2,4-butanetricarboxylate:NAD(+) oxidoreductase (decarboxylating) activity				EC:1.1.1.87|MetaCyc:1.1.1.87-RXN|RHEA:11900	Note that EC:1.1.1.155 was merged into EC:1.1.1.87 as they are identical.						GO:0047984		molecular_function											owl:Class	
GO:0102126	biolink:NamedThing	coniferyl aldehyde 5-hydroxylase activity	Catalysis of the reaction: H+ + coniferyl aldehyde + NADPH + O2 <=> 5-hydroxy-coniferaldehyde + NADP + H2O.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-1142									molecular_function											owl:Class	
GO:0102412	biolink:NamedThing	valerena-4,7(11)-diene synthase activity	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate(3-) <=> valerena-4,7(11)-diene + diphosphoric acid.	tmpzr1t_l9r_go_relaxed.owl					RHEA:34467|EC:4.2.3.139|MetaCyc:RXN-13769									molecular_function											owl:Class	
GO:1990231	biolink:NamedThing	STING complex	A protein dimer containing two STING monomers. It binds cyclic purine di-nucleotides.  Activation of the sting complex by 2',5'-3'-5'-cyclic GMP-AMP activates nuclear transcription factor kB (NF-kB) and interferon regulatory factor 3 (IRF3) which then induce transcription of the genes encoding type I IFN and cytokines active in the  innate immune response.	tmpzr1t_l9r_go_relaxed.owl	stimulator of interferon genes complex							bhm	2013-11-12T10:58:34Z					cellular_component											owl:Class	
GO:0097708	biolink:NamedThing	intracellular vesicle	Any vesicle that is part of the intracellular region.	tmpzr1t_l9r_go_relaxed.owl								pr	2016-03-29T17:39:45Z					cellular_component											owl:Class	
GO:0090348	biolink:NamedThing	regulation of cellular organofluorine metabolic process	Any process that modulates the rate, frequency or extent of the chemical reactions and pathways involving organofluorine compounds, as carried out by individual cells.	tmpzr1t_l9r_go_relaxed.owl								tb	2010-06-02T10:36:42Z					biological_process											owl:Class	
GO:0102776	biolink:NamedThing	UDP-D-glucose:pelargonidin-3-O-beta-D-glucoside 5-O-glucosyltransferase activity	Catalysis of the reaction: pelargonidin 3-O-beta-D-glucoside + UDP-alpha-D-glucose <=> anthocyanidin 3,5-di-O-beta-D-glucoside + UDP + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-7828									molecular_function											owl:Class	
GO:0042275	biolink:NamedThing	error-free postreplication DNA repair	The conversion of DNA-damage induced single-stranded gaps into large molecular weight DNA via processes such as template switching, which does not remove the replication-blocking lesions but does not increase the endogenous mutation rate.	tmpzr1t_l9r_go_relaxed.owl	error-free PRR|error-free replication restart					Note that 'error-free' does not mean that literally zero errors occur during DNA synthesis, but that the error rate is low, comparable to that of DNA synthesis during replication.								biological_process											owl:Class	
GO:0004375	biolink:NamedThing	glycine dehydrogenase (decarboxylating) activity	Catalysis of the reaction: glycine + lipoylprotein = S-aminomethyldihydrolipoylprotein + CO2.	tmpzr1t_l9r_go_relaxed.owl	glycine decarboxylase activity|protein P1|glycine-cleavage complex P-protein activity|glycine-cleavage complex|glycine:H-protein-lipoyllysine oxidoreductase (decarboxylating, acceptor-amino-methylating)|glycine:lipoylprotein oxidoreductase (decarboxylating and acceptor-aminomethylating)|glycine cleavage system P-protein activity|P-protein				MetaCyc:GCVP-RXN|EC:1.4.4.2|RHEA:24304|Reactome:R-HSA-5693967									molecular_function											owl:Class	
GO:0035851	biolink:NamedThing	Krueppel-associated box domain binding	Binding to a Krueppel-associated box (KRAB) domain of a protein. The approximately 75 amino acid KRAB domain is enriched in charged amino acids, and is found in the N-terminal regions of many zinc finger-containing transcription factors.	tmpzr1t_l9r_go_relaxed.owl	KRAB domain binding|Krueppel-associated box binding							bf	2011-05-11T11:41:16Z					molecular_function											owl:Class	
GO:1900947	biolink:NamedThing	regulation of isoprene biosynthetic process	Any process that modulates the frequency, rate or extent of isoprene biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of hemiterpene biosynthetic process|regulation of 2-methyl-1,3-butadiene biosynthesis|regulation of hemiterpene biosynthesis|regulation of 2-methyl-1,3-butadiene biosynthetic process							tt	2012-06-14T03:21:26Z					biological_process											owl:Class	
GO:0008457	biolink:NamedThing	beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity	Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide = UDP + N-acetyl-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide.	tmpzr1t_l9r_go_relaxed.owl	uridine diphosphoacetylglucosamine-acetyllactosaminide beta1->3-acetylglucosaminyltransferase|poly-N-acetyllactosamine extension enzyme activity|UDP-N-acetyl-D-glucosamine:beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide beta-1,3-acetylglucosaminyltransferase activity				RHEA:23004|MetaCyc:2.4.1.163-RXN|EC:2.4.1.149									molecular_function											owl:Class	
GO:0140382	biolink:NamedThing	tryptamine 4-monooxygenase activity	Catalysis of the reaction: tryptamine + reduced acceptor + O(2) <=> 4-hydroxytryptamine + acceptor + H(2)O.	tmpzr1t_l9r_go_relaxed.owl					EC:1.14.99.59|RHEA:15865			pg	2019-11-20T10:26:21Z					molecular_function											owl:Class	
GO:0001885	biolink:NamedThing	endothelial cell development	The progression of an endothelial cell over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1904483	biolink:NamedThing	synthetic cannabinoid binding	Binding to synthetic cannabinoid.	tmpzr1t_l9r_go_relaxed.owl								mr	2015-07-14T22:30:09Z					molecular_function											owl:Class	
GO:0034733	biolink:NamedThing	transcription factor TFIIIB-beta complex	A transcription factor TFIIIB-beta complex that contains the TATA-binding protein (TBP), B'' and BRF, and is involved in the regulation of transcription from type 2 RNA polymerase III promoters.	tmpzr1t_l9r_go_relaxed.owl						Note that the subunits of TFIIIB-beta are conserved between human and yeast; however, in yeast a single TFIIIB complex regulates transcription of tRNA, 5S rRNA and U6 snRNA genes, whereas two different TBP-dependent TFIIIB activities exist in humans.								cellular_component											owl:Class	
GO:0102168	biolink:NamedThing	5-methyl-phenazine-1-carboxylate N-methyltransferase activity	Catalysis of the reaction: phenazine-1-carboxylate + S-adenosyl-L-methionine  <=> 5-methylphenazine-1-carboxylate + S-adenosyl-L-homocysteine.	tmpzr1t_l9r_go_relaxed.owl					RHEA:49112|MetaCyc:RXN-11897									molecular_function											owl:Class	
GO:0045974	biolink:NamedThing	regulation of translation, ncRNA-mediated	Any process, mediated by small non-coding RNAs, that modulates the frequency, rate or extent that mRNAs are effectively translated into protein.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0031610	biolink:NamedThing	nuclear proteasome regulatory particle, base subcomplex	The subunits of the regulatory particle that directly associate with the core complex of a proteasome located in the nucleus of a cell.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:1901708	biolink:NamedThing	(+)-3'-hydroxylarreatricin biosynthetic process	The chemical reactions and pathways resulting in the formation of (+)-3'-hydroxylarreatricin.	tmpzr1t_l9r_go_relaxed.owl	(+)-3'-hydroxylarreatricin biosynthesis|(+)-3'-hydroxylarreatricin formation|(+)-3'-hydroxylarreatricin synthesis|(+)-3'-hydroxylarreatricin anabolism							ms	2012-12-19T14:39:32Z					biological_process											owl:Class	
GO:0034177	biolink:NamedThing	positive regulation of toll-like receptor 12 signaling pathway	Any process that activates or increases the frequency, rate, or extent of toll-like receptor 12 signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of toll-like receptor 12 signalling pathway|positive regulation of TLR12 signaling pathway													biological_process											owl:Class	
GO:0009132	biolink:NamedThing	nucleoside diphosphate metabolic process	The chemical reactions and pathways involving a nucleoside diphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with diphosphate on the sugar.	tmpzr1t_l9r_go_relaxed.owl	nucleoside diphosphate metabolism													biological_process											owl:Class	
GO:0008057	biolink:NamedThing	eye pigment granule organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of intracellular pigment storage granules in the eye.	tmpzr1t_l9r_go_relaxed.owl	eye pigment granule organisation|eye pigment granule organization and biogenesis											GO:0048751|GO:0045318|GO:0008059		biological_process											owl:Class	
GO:0048753	biolink:NamedThing	pigment granule organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a pigment granule.	tmpzr1t_l9r_go_relaxed.owl	pigment granule organisation|pigment granule organization and biogenesis													biological_process											owl:Class	
GO:0046487	biolink:NamedThing	glyoxylate metabolic process	The chemical reactions and pathways involving glyoxylate, the anion of glyoxylic acid, HOC-COOH.	tmpzr1t_l9r_go_relaxed.owl	glyoxylate metabolism													biological_process											owl:Class	
GO:0052716	biolink:NamedThing	hydroquinone:oxygen oxidoreductase activity	Catalysis of the reaction: 4 hydroquinone + O2 = 4 benzosemiquinone + 4 H2O.	tmpzr1t_l9r_go_relaxed.owl	p-diphenol:oxygen oxidoreductase activity|laccase reaction|benzenediol:oxygen oxidoreductase activity				KEGG_REACTION:R00083|RHEA:11276|MetaCyc:LACCASE-RXN|EC:1.10.3.2			ai	2011-08-11T03:18:19Z					molecular_function											owl:Class	
GO:0090322	biolink:NamedThing	regulation of superoxide metabolic process	Any process that modulates the rate, frequency, or extent of superoxide metabolism, the chemical reactions and pathways involving superoxide, the superoxide anion O2- (superoxide free radical), or any compound containing this species.	tmpzr1t_l9r_go_relaxed.owl	regulation of superoxide metabolism							tb	2010-05-06T02:29:05Z					biological_process											owl:Class	
GO:0090655	biolink:NamedThing	double-stranded/single-stranded junction telomeric DNA binding	Binding to a junction formed at the point where double-stranded telomeric DNA becomes a single-stranded G-rich telomeric DNA 3' overhang.	tmpzr1t_l9r_go_relaxed.owl								tb	2015-07-02T11:33:39Z					molecular_function											owl:Class	
GO:0000406	biolink:NamedThing	double-strand/single-strand DNA junction binding	Binding to a DNA segment that contains double-stranded DNA flanked by a region of single-stranded DNA.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0004522	biolink:NamedThing	ribonuclease A activity	Catalysis of the endonucleolytic cleavage of RNA to 3'-phosphomononucleotides and 3'-phosphooligonucleotides ending in C-P or U-P with 2',3'-cyclic phosphate intermediates.	tmpzr1t_l9r_go_relaxed.owl	gene S locus-specific glycoproteins|ribonucleic phosphatase activity|ceratitis capitata alkaline ribonuclease activity|S-genotype-assocd. glycoproteins|RNase activity|SLSG glycoproteins|gene S glycoproteins|RNase A activity|ribonucleate 3'-pyrimidino-oligonucleotidohydrolase activity|endoribonuclease I|alkaline ribonuclease activity|pancreatic RNase activity|ribonuclease I activity|RNase I activity|pancreatic ribonuclease activity				MetaCyc:3.1.27.5-RXN|EC:4.6.1.18|Wikipedia:Ribonuclease_A									molecular_function											owl:Class	
GO:0015526	biolink:NamedThing	hexose-phosphate:inorganic phosphate antiporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: hexose phosphate(out) + inorganic phosphate(in) = hexose phosphate(in) + inorganic phosphate(out).	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0008031	biolink:NamedThing	eclosion hormone activity	The action characteristic of eclosion hormone, a peptide hormone that, upon receptor binding, triggers the death of certain muscles and neurons during insect metamorphosis.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0046714	biolink:NamedThing	borate binding	Binding to borate, the anion (BO3)3-.	tmpzr1t_l9r_go_relaxed.owl	boron binding													molecular_function											owl:Class	
GO:0046439	biolink:NamedThing	L-cysteine metabolic process	The chemical reactions and pathways involving L-cysteine, the L-enantiomer of 2-amino-3-mercaptopropanoic acid, i.e. (2R)-2-amino-3-mercaptopropanoic acid.	tmpzr1t_l9r_go_relaxed.owl	L-cysteine metabolism													biological_process											owl:Class	
GO:0030779	biolink:NamedThing	10-hydroxydihydrosanguinarine 10-O-methyltransferase activity	Catalysis of the reaction: 10-hydroxydihydrosanguinarine + S-adenosyl-L-methionine(1+) = S-adenosyl-L-homocysteine + dihydrochelirubine + H(+).	tmpzr1t_l9r_go_relaxed.owl	S-adenosyl-L-methionine:10-hydroxydihydrosanguinarine 10-O-methyltransferase activity				KEGG_REACTION:R04707|MetaCyc:2.1.1.119-RXN|RHEA:18541|EC:2.1.1.119									molecular_function											owl:Class	
GO:0045497	biolink:NamedThing	female analia development	The process whose specific outcome is the progression of the analia of the female over time, from formation to the mature structure. The analia is the posterior-most vertral appendage that develops from the genital disc. An example of this process is found in Drosophila melanogaster.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0007487	biolink:NamedThing	analia development	The process whose specific outcome is the progression of the analia over time, from its formation to the mature structure. The analia is the posterior-most vertral appendage that develops from the genital disc. An example of this process is analia development in Drosophila melanogaster.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0046524	biolink:NamedThing	sucrose-phosphate synthase activity	Catalysis of the reaction: UDP-glucose + D-fructose 6-phosphate = UDP + sucrose 6-phosphate.	tmpzr1t_l9r_go_relaxed.owl	sucrosephosphate-UDP glucosyltransferase activity|SPS|sucrose phosphate synthetase activity|UDPglucose:D-fructose-6-phosphate 2-alpha-D-glucosyltransferase activity|UDP-glucose-fructose-phosphate glucosyltransferase activity|UDP-glucose:D-fructose-6-phosphate 2-alpha-D-glucosyltransferase activity|sucrose phosphate-uridine diphosphate glucosyltransferase activity|sucrose 6-phosphate synthase activity|UDPglucose-fructose-phosphate glucosyltransferase activity|uridine diphosphoglucose-fructose phosphate glucosyltransferase activity				MetaCyc:SUCROSE-PHOSPHATE-SYNTHASE-RXN|EC:2.4.1.14|RHEA:22172									molecular_function											owl:Class	
GO:0048874	biolink:NamedThing	host-mediated regulation of intestinal microbiota composition	The biological process involved in maintaining the steady-state number of cells within a population of free-living cells such as the bacteria in the gut.	tmpzr1t_l9r_go_relaxed.owl	host-induced regulation of intestinal microbiota composition|homeostasis of number of cells in a free-living population	https://github.com/geneontology/go-ontology/issues/15748												biological_process											owl:Class	
GO:0031107	biolink:NamedThing	septin ring disassembly	The controlled breakdown of a septin ring.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0034460	biolink:NamedThing	uropod assembly	The assembly of a uropod by rearrangement of the cytoskeleton and overlying membrane.	tmpzr1t_l9r_go_relaxed.owl	uropod formation													biological_process											owl:Class	
GO:0004809	biolink:NamedThing	tRNA (guanine-N2-)-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + tRNA containing guanine = S-adenosyl-L-homocysteine + tRNA containing N2-methylguanine.	tmpzr1t_l9r_go_relaxed.owl	tRNA 2,2-dimethylguanosine-26 methyltransferase activity|tRNA(m(2,2)G26)dimethyltransferase activity|transfer ribonucleate guanine 2-methyltransferase activity|N2,N2-dimethylguanine tRNA methyltransferase activity|S-adenosyl-L-methionine:tRNA (guanine-N2-)-methyltransferase activity|transfer ribonucleate guanine N2-methyltransferase activity|N(2),N(2)-dimethylguanine tRNA methyltransferase activity|S-adenosyl-L-methionine:tRNA (guanine-2-N-)-methyltransferase activity|transfer RNA guanine 2-methyltransferase activity|guanine-N2-methylase activity|tRNA(guanine-26,N(2)-N(2)) methyltransferase activity|tRNA(guanine-26,N2-N2) methyltransferase activity				Reactome:R-HSA-6786501|Reactome:R-HSA-6782416									molecular_function											owl:Class	
GO:0035354	biolink:NamedThing	Toll-like receptor 1-Toll-like receptor 2 protein complex	A heterodimeric protein complex containing Toll-like receptor 1 (TLR1) and Toll-like receptor 2 (TLR2).	tmpzr1t_l9r_go_relaxed.owl	TLR1:TLR2 complex|TLR1-TLR2 protein complex|TLR2:TLR1 heterodimer|toll-like receptor TLR1:TLR2 heterodimeric complex							bf	2010-03-04T04:35:44Z			GO:0038125		cellular_component											owl:Class	
GO:0043627	biolink:NamedThing	response to estrogen	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by an estrogen, C18 steroid hormones that can stimulate the development of female sexual characteristics.	tmpzr1t_l9r_go_relaxed.owl	response to oestrogen stimulus|response to estrogen stimulus													biological_process											owl:Class	
GO:0033489	biolink:NamedThing	cholesterol biosynthetic process via desmosterol	The chemical reactions and pathways resulting in the formation of cholesterol, cholest-5-en-3 beta-ol, via the intermediate desmosterol.	tmpzr1t_l9r_go_relaxed.owl	cholesterol formation via desmosterol|cholesterol synthesis via desmosterol|cholesterol biosynthesis via desmosterol|cholesterol anabolism via desmosterol				MetaCyc:PWY66-4									biological_process											owl:Class	
GO:1900636	biolink:NamedThing	heptadecane biosynthetic process	The chemical reactions and pathways resulting in the formation of heptadecane.	tmpzr1t_l9r_go_relaxed.owl	heptadecane synthesis|heptadecane anabolism|heptadecane formation|heptadecane biosynthesis							tt	2012-05-21T07:05:21Z					biological_process											owl:Class	
GO:0034932	biolink:NamedThing	1-methoxypyrene 6,7-monooxygenase activity	Catalysis of the reaction: 1-methoxypyrene + O2 + 2 H+ + 2 e- = 1-methoxypyrene-6,7-oxide + H2O.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0954									molecular_function											owl:Class	
GO:0046509	biolink:NamedThing	1,2-diacylglycerol 3-beta-galactosyltransferase activity	Catalysis of the reaction: 1,2-diacyl-sn-glycerol + UDP-D-galactose = 1,2-diacyl-3-beta-D-galactosyl-sn-glycerol + H(+) + UDP.	tmpzr1t_l9r_go_relaxed.owl	UDP galactose-1,2-diacylglycerol galactosyltransferase activity|UDPgalactose:1,2-diacylglycerol 3-beta-D-galactosyltransferase activity|MGDG synthase activity|UDP-galactose-diacylglyceride galactosyltransferase activity|1-beta-MGDG activity|monogalactosyldiacylglycerol synthase activity|uridine diphosphogalactose-1,2-diacylglycerol galactosyltransferase activity|UDP-galactose:1,2-diacyl-sn-glycerol 3-beta-D-galactosyltransferase activity|1beta-MGDG|UDP-galactose:diacylglycerol galactosyltransferase activity				KEGG_REACTION:R02691|EC:2.4.1.46|MetaCyc:2.4.1.46-RXN|RHEA:14945									molecular_function											owl:Class	
GO:0043918	biolink:NamedThing	cadaverine aminopropyltransferase activity	Catalysis of the reaction: S-adenosylmethioninamine + cadaverine = 5'-methylthioadenosine + N-(3-aminopropyl)cadaverine.	tmpzr1t_l9r_go_relaxed.owl	cadaverine aminopropyl transferase activity				EC:2.5.1.104									molecular_function											owl:Class	
GO:0019513	biolink:NamedThing	lactose catabolic process, using glucoside 3-dehydrogenase	The chemical reactions and pathways resulting in the breakdown of lactose, catalyzed by the enzyme glucoside 3-dehydrogenase (EC:1.1.99.13).	tmpzr1t_l9r_go_relaxed.owl	lactose degradation, using glucoside 3-dehydrogenase|lactose breakdown, using glucoside 3-dehydrogenase				MetaCyc:LACTOSEUTIL-PWY									biological_process											owl:Class	
GO:0060282	biolink:NamedThing	positive regulation of oocyte development	Any process that increases the rate or extent of the process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0033327	biolink:NamedThing	Leydig cell differentiation	The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a Leydig cell. A Leydig cell is a testosterone-secreting cell in the interstitial area, between the seminiferous tubules, in the testis.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0036249	biolink:NamedThing	cadmium ion import into vacuole	The directed movement of cadmium ions into the vacuole.	tmpzr1t_l9r_go_relaxed.owl	vacuolar cadmium import							bf	2012-05-31T11:13:44Z					biological_process											owl:Class	
GO:0060420	biolink:NamedThing	regulation of heart growth	Any process that modulates the rate or extent of heart growth. Heart growth is the increase in size or mass of the heart.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0018228	biolink:NamedThing	peptidyl-S-geranylgeranyl-L-cysteine biosynthetic process from peptidyl-cysteine	The modification of peptidyl-cysteine to form peptidyl-S-geranylgeranylcysteine; formation of S-geranylgeranyl-L-cysteine may be coupled with subsequent cleavage of a carboxy-terminal tripeptide for the CAAX motif and methyl esterification of the geranylgeranylated cysteine; methyl esterification but not cleavage occurs for the CXC motif. For the type II geranylgeranyltransferase the residue may be found at the first and final positions in the sequence motif C-X-C* or at the final position in the sequence motif C-C*. These motifs are necessary but not sufficient for modification.	tmpzr1t_l9r_go_relaxed.owl	peptidyl-S-geranylgeranyl-L-cysteine anabolism from peptidyl-cysteine|peptidyl-S-geranylgeranyl-L-cysteine formation from peptidyl-cysteine|peptidyl-S-geranylgeranyl-L-cysteine synthesis from peptidyl-cysteine				RESID:AA0104									biological_process											owl:Class	
GO:0050282	biolink:NamedThing	serine 2-dehydrogenase activity	Catalysis of the reaction: L-serine + H2O + NAD+ = 3-hydroxypyruvate + NH3 + NADH.	tmpzr1t_l9r_go_relaxed.owl	L-serine:NAD oxidoreductase (deaminating) activity|L-serine:NAD+ 2-oxidoreductase (deaminating)|serine dehydrogenase activity				EC:1.4.1.7|RHEA:20884|MetaCyc:SERINE-DEHYDROGENASE-RXN									molecular_function											owl:Class	
GO:0005951	biolink:NamedThing	carbamoyl-phosphate synthase complex	A protein complex that catalyzes the formation of carbamoyl phosphate; comprises a small subunit that binds and cleaves glutamine, and a large subunit that accepts the ammonia group cleaved from glutamine, binds all of the remaining substrates and effectors, and carries out all of the other catalytic events.	tmpzr1t_l9r_go_relaxed.owl	arginine-specific carbamoyl phosphate synthetase complex|carbamoyl phosphate synthase complex|carbamoyl-phosphate synthase arginine-specific complex					Note that in higher eukaryotes, carbamoyl-phosphate synthase is usually a single polypeptide, not a complex, and should therefore not be annotated to this component term.								cellular_component											owl:Class	
GO:0070614	biolink:NamedThing	tungstate ion transport	The directed movement of tungstate (WO4 2-) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Tungstate is a bivalent oxoanion of tungsten.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-04-29T03:07:40Z					biological_process											owl:Class	
GO:0016281	biolink:NamedThing	eukaryotic translation initiation factor 4F complex	The eukaryotic translation initiation factor 4F complex is composed of eIF4E, eIF4A and eIF4G; it is involved in the recognition of the mRNA cap, ATP-dependent unwinding of the 5'-terminal secondary structure and recruitment of the mRNA to the ribosome.	tmpzr1t_l9r_go_relaxed.owl	eIF-4F|eukaryotic translation initiation factor 4 complex													cellular_component											owl:Class	
GO:0018147	biolink:NamedThing	molybdenum incorporation via L-selenocysteinyl molybdenum bis(molybdopterin guanine dinucleotide)	The incorporation of molybdenum into a protein via L-selenocysteinyl molybdenum bis(molybdopterin guanine dinucleotide).	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0248									biological_process											owl:Class	
GO:0050844	biolink:NamedThing	peptidyl-selenocysteine modification	The modification of peptidyl-selenocysteine.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0010432	biolink:NamedThing	bract development	The process whose specific outcome is the progression of the bract over time, from its formation to the mature structure. A bract is a leaf, usually different in form from the foliage leaves, subtending a flower or inflorescence.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0039646	biolink:NamedThing	modulation by virus of host G0/G1 transition checkpoint	Any viral process that modulates the frequency, rate or extent of the host cell G0/G1 transition checkpoint.	tmpzr1t_l9r_go_relaxed.owl	G0/G1 host cell cycle checkpoint dysregulation by virus				VZ:881			bf	2012-10-09T15:11:22Z					biological_process											owl:Class	
GO:0047435	biolink:NamedThing	5-guanidino-2-oxopentanoate decarboxylase activity	Catalysis of the reaction: 5-guanidino-2-oxopentanoate + H(+) = 4-guanidinobutanal + CO(2).	tmpzr1t_l9r_go_relaxed.owl	2-oxo-5-guanidinopentanoate decarboxylase activity|2-oxo-5-guanidinopentanoate carboxy-lyase (4-guanidinobutanal-forming)|alpha-ketoarginine decarboxylase activity|2-oxo-5-guanidinopentanoate carboxy-lyase activity|2-oxo-5-guanidinovalerate alpha-ketoarginine decarboxylase activity				RHEA:11340|KEGG_REACTION:R03178|MetaCyc:4.1.1.75-RXN|EC:4.1.1.75									molecular_function											owl:Class	
GO:0070655	biolink:NamedThing	mechanosensory epithelium regeneration	The regrowth of lost or destroyed mechanosensory epithelia.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-05-28T04:05:18Z					biological_process											owl:Class	
GO:0070654	biolink:NamedThing	sensory epithelium regeneration	The regrowth of a sensory epithelium following its loss or destruction.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-05-28T04:02:27Z					biological_process											owl:Class	
GO:0018403	biolink:NamedThing	protein-dermatan sulfate linkage via dermatan 4-sulfate D-glucuronyl-D-galactosyl-D-galactosyl-D-xylosyl-L-serine	Dermatan sulfate components are covalently linked to a core glycoprotein via O-glycosidic linkages between xylose and serine residues.	tmpzr1t_l9r_go_relaxed.owl	protein-dermatan sulphate linkage via dermatan 4-sulphate D-glucuronyl-D-galactosyl-D-galactosyl-D-xylosyl-L-serine				RESID:AA0209									biological_process											owl:Class	
GO:0015703	biolink:NamedThing	chromate transport	The directed movement of chromate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1903199	biolink:NamedThing	negative regulation of L-dopa decarboxylase activity	Any process that stops, prevents or reduces the frequency, rate or extent of L-dopa decarboxylase activity.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of DDC activity|downregulation of DDC activity|down regulation of L-dopa decarboxylase activity|down-regulation of DDC activity|down regulation of DOPA decarboxylase activity|inhibition of 4-dihydroxyl-L-phenylalanine decarboxylase activity|negative regulation of 4-dihydroxyl-L-phenylalanine decarboxylase activity|inhibition of DDC activity|down regulation of 4-dihydroxyl-L-phenylalanine decarboxylase activity|downregulation of DOPA decarboxylase activity|downregulation of 4-dihydroxyl-L-phenylalanine decarboxylase activity|downregulation of L-dopa decarboxylase activity|inhibition of DOPA decarboxylase activity|down-regulation of L-dopa decarboxylase activity|inhibition of L-dopa decarboxylase activity|down regulation of DDC activity|down-regulation of 4-dihydroxyl-L-phenylalanine decarboxylase activity|down-regulation of DOPA decarboxylase activity|negative regulation of DOPA decarboxylase activity							bf	2014-07-21T09:32:37Z					biological_process											owl:Class	
GO:0075277	biolink:NamedThing	positive regulation of telium development	Any process that activates, maintains or increases the frequency, rate or extent of telium development, a process that leads to the formation of a teliospore-bearing sorus of the rust fungi.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0106341	biolink:NamedThing	omega-hydroxyceramide transacylase activity	Catalysis of the reaction: 1,2,3-tri-(9Z,12Z)-octadecadienoylglycerol + N-(30-hydroxytriacontanoyl)-sphing-4-enine = di-(9Z,12Z)-octadecadienoylglycerol + N-[30-(9Z,12Z-octadecadienoyloxy)-triacontanoyl]-sphing-4-enine.	tmpzr1t_l9r_go_relaxed.owl					RHEA:55264			hjd	2020-11-17T17:12:43Z					molecular_function											owl:Class	
GO:0102914	biolink:NamedThing	N-methyl-3-aminomethylindole N-methyltransferase activity	Catalysis of the reaction: N-methyl-3-aminomethylindole + S-adenosyl-L-methionine  = H+ + gramine + S-adenosyl-L-homocysteine.	tmpzr1t_l9r_go_relaxed.owl					RHEA:52272|MetaCyc:RXN-8687									molecular_function											owl:Class	
GO:0140331	biolink:NamedThing	aminophospholipid translocation	The movement of an aminophospholipid molecule from one leaflet of a membrane bilayer to the opposite leaflet.	tmpzr1t_l9r_go_relaxed.owl								pg	2019-05-10T13:46:34Z					biological_process											owl:Class	
GO:0003921	biolink:NamedThing	GMP synthase activity	Catalysis of the reaction: ATP + XMP + NH4(+) = AMP + diphosphate + GMP + 2H(+).	tmpzr1t_l9r_go_relaxed.owl					RHEA:18301|MetaCyc:GMP-SYN-NH3-RXN									molecular_function											owl:Class	
GO:0047042	biolink:NamedThing	androsterone dehydrogenase (B-specific) activity	Catalysis of the reaction: NAD(P)+ + androsterone = NAD(P)H + H+ + 5-alpha-androstane-3,17-dione. The reaction is B-specific (i.e. the pro-S hydrogen is transferred from the 4-position of reduced nicotinamide cofactor) with respect to NAD(P)+.	tmpzr1t_l9r_go_relaxed.owl	3-alpha-HSD activity|3alpha-hydroxysteroid:NAD(P)+ oxidoreductase (B-specific)|sterognost 3alpha|hydroxyprostaglandin dehydrogenase activity|3alpha-hydroxysteroid oxidoreductase activity|3alpha-HSD|3alpha-hydroxysteroid dehydrogenase (B-specific)|3-alpha-hydroxysteroid dehydrogenase (B-specific) activity				Wikipedia:3alpha-hydroxysteroid_dehydrogenase_(B-specific)|EC:1.1.1.50|MetaCyc:1.1.1.50-RXN									molecular_function											owl:Class	
GO:0047023	biolink:NamedThing	androsterone dehydrogenase activity	Catalysis of the reaction: NAD(P)+ + androsterone = NAD(P)H + H+ + 5-alpha-androstane-3,17-dione.	tmpzr1t_l9r_go_relaxed.owl	3(or 17)alpha-hydroxysteroid:NAD(P)+ oxidoreductase activity|3(17)alpha-hydroxysteroid dehydrogenase activity|3(or 17)-alpha-hydroxysteroid dehydrogenase activity|3(or 17)alpha-hydroxysteroid dehydrogenase activity				EC:1.1.1.209|MetaCyc:1.1.1.209-RXN									molecular_function											owl:Class	
GO:0097084	biolink:NamedThing	vascular associated smooth muscle cell development	The process aimed at the progression of a vascular smooth muscle cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. A vascular smooth muscle cell is a non-striated, elongated, spindle-shaped cell found lining the blood vessels.	tmpzr1t_l9r_go_relaxed.owl	vascular smooth muscle cell development							pr	2011-06-20T04:03:08Z					biological_process											owl:Class	
GO:0150091	biolink:NamedThing	multiple spine synapse organization, multiple dendrites	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a synapse between a multiple synapse bouton and two or more dendritic spines protruding either from a single dendrite or from multiple dendrites.	tmpzr1t_l9r_go_relaxed.owl								bc	2018-08-08T15:05:29Z					biological_process											owl:Class	
GO:0032221	biolink:NamedThing	Rpd3S/Clr6-CII complex	A eukaryotically conserved histone deacetylase complex which deacetylates histones across gene coding regions. Composed of a catalytic histone deacetylase subunit, a chromodomain protein, a SIN3 family co-repressor, and a WD repeat protein (Clr6p, Alp13p, Pst2p, and Prw1p respectively in Schizosaccharomyces; Rpd3p, Sin3p, Ume1p, Rco1p and Eaf3 in Saccharomyces; homologs thereof in other species).	tmpzr1t_l9r_go_relaxed.owl	Clr6-CII|Clr6 histone deacetylase complex II'|Clr6 histone deacetylase complex II|Clr6S complex|Rpd3S complex|Rpd3C(S)	https://github.com/geneontology/go-ontology/issues/19819										GO:0000509		cellular_component											owl:Class	
GO:0050415	biolink:NamedThing	formimidoylglutamase activity	Catalysis of the reaction: N-formimidoyl-L-glutamate + H(2)O = L-glutamate + formamide.	tmpzr1t_l9r_go_relaxed.owl	N-formiminoglutamate hydrolase activity|formiminoglutamase activity|N-formimino-L-glutamate formiminohydrolase activity|N-formimidoyl-L-glutamate formimidoylhydrolase activity|formiminoglutamate hydrolase activity				EC:3.5.3.8|RHEA:22492|MetaCyc:FORMIMINOGLUTAMASE-RXN|KEGG_REACTION:R02285									molecular_function											owl:Class	
GO:0018064	biolink:NamedThing	protein-L-histidine N-tele-methyltransferase activity	Catalysis of the reaction: L-histidyl-[protein] + S-adenosyl-L-methionine = N(tele)-methyl-L-histidyl-[protein] + S-adenosyl-L-homocysteine.	tmpzr1t_l9r_go_relaxed.owl	protein (histidine) methyltransferase activity|actin-specific histidine methyltransferase activity|S-adenosyl-L-methionine:protein-L-histidine N-tele-methyltransferase activity|protein methylase IV activity|S-adenosyl methionine:protein-histidine N-methyltransferase activity|protein-histidine N-methyltransferase activity|peptidyl-histidine N-methyltransferase activity				RHEA:19369|EC:2.1.1.85|MetaCyc:2.1.1.85-RXN									molecular_function											owl:Class	
GO:0018032	biolink:NamedThing	protein amidation	Addition of an amide group from a glycine to a protein amino acid.	tmpzr1t_l9r_go_relaxed.owl	protein amino acid amidation													biological_process											owl:Class	
GO:2000271	biolink:NamedThing	positive regulation of fibroblast apoptotic process	Any process that activates or increases the frequency, rate or extent of fibroblast apoptotic process.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of fibroblast apoptosis							jl	2010-11-23T01:07:29Z					biological_process											owl:Class	
GO:2000384	biolink:NamedThing	negative regulation of ectoderm development	Any process that stops, prevents or reduces the frequency, rate or extent of ectoderm development.	tmpzr1t_l9r_go_relaxed.owl								vk	2011-02-15T03:17:27Z					biological_process											owl:Class	
GO:1903942	biolink:NamedThing	positive regulation of respiratory gaseous exchange	Any process that activates or increases the frequency, rate or extent of respiratory gaseous exchange.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of respiratory gaseous exchange|activation of respiratory gaseous exchange|up regulation of respiratory gaseous exchange|upregulation of respiratory gaseous exchange							sl	2015-02-17T20:26:35Z					biological_process											owl:Class	
GO:0102191	biolink:NamedThing	4alpha-carboxy-5alpha-cholesta-7,24-dien-3beta-ol dehydrogenase/C4-decarboxylase activity	Catalysis of the reaction: 4alpha-carboxy-5alpha-cholesta-7,24-dien-3beta-ol + NAD(1-) <=> 5alpha-cholesta-7,24-dien-3-one + NADH(2-) + carbon dioxide.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-11959|RHEA:59016|EC:1.1.1.418									molecular_function											owl:Class	
GO:0150191	biolink:NamedThing	positive regulation of interleukin-32 production	Any process that activates or increases the frequency, rate or extent of interleukin-32 production.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of interleukin-32 biosynthetic process|positive regulation of interleukin-32 secretion							bc	2020-02-21T10:33:39Z			GO:0150194		biological_process											owl:Class	
GO:0019397	biolink:NamedThing	gallate catabolic process via 2-pyrone-4,6-dicarboxylate	The chemical reactions and pathways resulting in the breakdown of gallate, the anion of gallic acid, via the intermediate 2-pyrone-4,6-dicarboxylate.	tmpzr1t_l9r_go_relaxed.owl	gallic acid catabolic process via 2-pyrone-4,6-dicarboxylate|gallate breakdown via 2-pyrone-4,6-dicarboxylate|gallate degradation via 2-pyrone-4,6-dicarboxylate|gallic acid catabolism via 2-pyrone-4,6-dicarboxylate				MetaCyc:GALLATE-DEGRADATION-I-PWY									biological_process											owl:Class	
GO:0015963	biolink:NamedThing	diadenosine triphosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of diadenosine triphosphate, a derivative of the nucleoside adenosine with three phosphate groups attached.	tmpzr1t_l9r_go_relaxed.owl	diadenosine triphosphate synthesis|diadenosine triphosphate formation|diadenosine triphosphate biosynthesis|diadenosine triphosphate anabolism													biological_process											owl:Class	
GO:0015962	biolink:NamedThing	diadenosine triphosphate metabolic process	The chemical reactions and pathways involving diadenosine triphosphate, a derivative of the nucleoside adenosine with three phosphate groups attached.	tmpzr1t_l9r_go_relaxed.owl	diadenosine triphosphate metabolism													biological_process											owl:Class	
GO:0002357	biolink:NamedThing	defense response to tumor cell	Reactions triggered in response to the presence of a tumor cell that act to protect the cell or organism.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1903013	biolink:NamedThing	response to differentiation-inducing factor 1	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one|response to DIF-1|DIF-1|response to DIF1							rjd	2014-05-14T16:18:11Z					biological_process											owl:Class	
GO:0060778	biolink:NamedThing	primary leaflet morphogenesis	The process in which the primary leaflet attains its shape. A primary leaflet is a leaflet that develops directly from the rachis.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-07-25T07:15:48Z					biological_process											owl:Class	
GO:0002771	biolink:NamedThing	inhibitory killer cell immunoglobulin-like receptor signaling pathway	A series of molecular signals initiated by the binding of an extracellular ligand to a inhibitory killer cell immunoglobulin-like receptor capable of inhibiting an immune effector process contributing to an immune response.	tmpzr1t_l9r_go_relaxed.owl	KIR signaling pathway|inhibitory killer cell immunoglobulin-like receptor signalling pathway|killer cell inhibitory receptor signaling pathway													biological_process											owl:Class	
GO:0030122	biolink:NamedThing	AP-2 adaptor complex	A heterotetrameric AP-type membrane coat adaptor complex that consists of alpha, beta2, mu2 and sigma2 subunits, and links clathrin to the membrane surface of a vesicle, and the cargo receptors during receptor/clathrin mediated endocytosis. Vesicles with AP-2-containing coats are normally found primarily near the plasma membrane, on endocytic vesicles. In at least humans, the AP-2 complex can be heterogeneric due to the existence of multiple subunit isoforms encoded by different alpha genes (alphaA and alphaC).	tmpzr1t_l9r_go_relaxed.owl	HA2 clathrin adaptor|HA2													cellular_component											owl:Class	
GO:0031905	biolink:NamedThing	early endosome lumen	The volume enclosed by the membrane of an early endosome.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0043830	biolink:NamedThing	thiol-driven fumarate reductase activity	Catalysis of the reaction: fumarate + coenzyme M + coenzyme B = succinate + coenzyme M + coenzyme B + heterodisulfide.	tmpzr1t_l9r_go_relaxed.owl					EC:1.3.99.-									molecular_function											owl:Class	
GO:0008909	biolink:NamedThing	isochorismate synthase activity	Catalysis of the reaction: chorismate = isochorismate.	tmpzr1t_l9r_go_relaxed.owl	isochorismate hydroxymutase activity|isochorismate synthetase activity|isochorismate mutase activity				KEGG_REACTION:R01717|RHEA:18985|EC:5.4.4.2|MetaCyc:ISOCHORSYN-RXN	Note that this function was formerly EC:5.4.99.6.								molecular_function											owl:Class	
GO:0033153	biolink:NamedThing	T cell receptor V(D)J recombination	The process in which T cell receptor V, D, and J, or V and J gene segments, depending on the specific locus, are recombined within a single locus utilizing the conserved heptamer and nonomer recombination signal sequences (RSS).	tmpzr1t_l9r_go_relaxed.owl	T cell receptor V-D-J joining|T cell receptor V-D-J recombination|T-cell receptor V(D)J recombination|T cell receptor V-J recombination|T cell receptor V(D)J joining|T cell receptor V-J joining|TCR V(D)J recombination													biological_process											owl:Class	
GO:1904972	biolink:NamedThing	negative regulation of viral translation	Any process that stops, prevents or reduces the frequency, rate or extent of viral translation.	tmpzr1t_l9r_go_relaxed.owl	inhibition of viral protein biosynthetic process|downregulation of viral protein anabolism|inhibition of viral protein anabolism|down regulation of viral protein biosynthesis|inhibition of viral protein synthesis|down-regulation of viral protein anabolism|down-regulation of viral translation|down-regulation of viral protein formation|down regulation of viral protein formation|inhibition of viral protein formation|downregulation of viral protein biosynthesis|downregulation of viral translation|down regulation of viral protein biosynthetic process|negative regulation of viral protein anabolism|down regulation of viral translation|down-regulation of viral protein synthesis|negative regulation of viral protein biosynthetic process|downregulation of viral protein synthesis|negative regulation of viral protein biosynthesis|downregulation of viral protein formation|down regulation of viral protein anabolism|negative regulation of viral protein formation|inhibition of viral protein biosynthesis|down regulation of viral protein synthesis|down-regulation of viral protein biosynthetic process|inhibition of viral translation|downregulation of viral protein biosynthetic process|negative regulation of viral protein synthesis|down-regulation of viral protein biosynthesis							bhm	2016-02-17T15:53:08Z					biological_process											owl:Class	
GO:0038085	biolink:NamedThing	vascular endothelial growth factor binding	Binding to a vascular endothelial growth factor.	tmpzr1t_l9r_go_relaxed.owl	VEGF binding							bf	2012-02-01T02:36:36Z					molecular_function											owl:Class	
GO:0097519	biolink:NamedThing	DNA recombinase complex	A protein-DNA complex consisting of a higher-order oligomer of strand exchange proteins (recombinases) on single-stranded DNA.	tmpzr1t_l9r_go_relaxed.owl								pr	2013-10-16T15:43:22Z					cellular_component											owl:Class	
GO:1902853	biolink:NamedThing	negative regulation of nuclear migration during mitotic telophase	Any process that stops, prevents or reduces the frequency, rate or extent of nuclear migration during mitotic telophase.	tmpzr1t_l9r_go_relaxed.owl	downregulation of nuclear migration during mitotic telophase|inhibition of nuclear migration during mitotic telophase|down-regulation of nuclear migration during mitotic telophase|down regulation of nuclear migration during mitotic telophase							vw	2014-04-02T15:35:56Z					biological_process											owl:Class	
GO:1902839	biolink:NamedThing	negative regulation of nuclear migration along microtubule	Any process that stops, prevents or reduces the frequency, rate or extent of nuclear migration along microtubule.	tmpzr1t_l9r_go_relaxed.owl	inhibition of transport of nucleus, microtubule-mediated|downregulation of nuclear migration, microtubule-mediated|down regulation of nuclear migration, microtubule-mediated|down regulation of microtubule cytoskeleton-dependent nuclear positioning|down-regulation of transport of nucleus, microtubule-mediated|negative regulation of transport of nucleus by microtubules|negative regulation of transport of nucleus, microtubule-mediated|down-regulation of microtubule cytoskeleton-dependent nucleus positioning|downregulation of microtubule-dependent nucleus positioning|negative regulation of nuclear migration, microtubule-mediated|down regulation of microtubule-dependent nuclear positioning|down-regulation of nuclear migration, microtubule-mediated|down regulation of nuclear migration along microtubule|down-regulation of microtubule-dependent nucleus positioning|inhibition of microtubule-mediated nuclear migration|inhibition of microtubule cytoskeleton-dependent nucleus positioning|inhibition of nuclear migration, microtubule-mediated|negative regulation of microtubule-mediated nuclear migration|down regulation of microtubule cytoskeleton-dependent nucleus positioning|downregulation of transport of nucleus, microtubule-mediated|negative regulation of microtubule cytoskeleton-dependent nucleus positioning|inhibition of nuclear migration along microtubule|downregulation of nuclear migration along microtubule|down-regulation of transport of nucleus by microtubules|down-regulation of nuclear migration along microtubule|negative regulation of microtubule-dependent nuclear positioning|down regulation of microtubule-dependent nucleus positioning|downregulation of microtubule cytoskeleton-dependent nucleus positioning|negative regulation of microtubule-dependent nucleus positioning|down regulation of microtubule-mediated nuclear migration|downregulation of microtubule-dependent nuclear positioning|inhibition of microtubule-dependent nucleus positioning|downregulation of microtubule cytoskeleton-dependent nuclear positioning|down regulation of transport of nucleus by microtubules|negative regulation of microtubule cytoskeleton-dependent nuclear positioning|inhibition of microtubule cytoskeleton-dependent nuclear positioning|inhibition of microtubule-dependent nuclear positioning|inhibition of transport of nucleus by microtubules|down-regulation of microtubule-mediated nuclear migration|down-regulation of microtubule cytoskeleton-dependent nuclear positioning|downregulation of microtubule-mediated nuclear migration|down-regulation of microtubule-dependent nuclear positioning|downregulation of transport of nucleus by microtubules|down regulation of transport of nucleus, microtubule-mediated							vw	2014-04-01T13:50:29Z					biological_process											owl:Class	
GO:1903105	biolink:NamedThing	negative regulation of insulin receptor signaling pathway involved in determination of adult lifespan	Any process that stops, prevents or reduces the frequency, rate or extent of insulin receptor signaling pathway involved in determination of adult lifespan.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of daf-2 receptor signaling pathway of determination of adult lifespan|down-regulation of insulin receptor signalling pathway of determination of adult lifespan|down regulation of insulin receptor signalling pathway of determination of adult lifespan|downregulation of insulin receptor signaling pathway of determination of adult lifespan|down-regulation of daf-2 receptor signaling pathway of determination of adult lifespan|down-regulation of insulin receptor signaling pathway of determination of adult lifespan|down regulation of insulin receptor signaling pathway of determination of adult lifespan|inhibition of daf-2 receptor signaling pathway of determination of adult lifespan|inhibition of insulin receptor signalling pathway of determination of adult lifespan|negative regulation of insulin receptor signaling pathway of determination of adult lifespan|down-regulation of insulin receptor signaling pathway involved in determination of adult lifespan|inhibition of insulin receptor signaling pathway of determination of adult lifespan|inhibition of insulin receptor signaling pathway involved in determination of adult lifespan|negative regulation of insulin receptor signalling pathway of determination of adult lifespan|downregulation of insulin receptor signaling pathway involved in determination of adult lifespan|downregulation of insulin receptor signalling pathway of determination of adult lifespan|down regulation of insulin receptor signaling pathway involved in determination of adult lifespan|down regulation of daf-2 receptor signaling pathway of determination of adult lifespan|downregulation of daf-2 receptor signaling pathway of determination of adult lifespan							kmv	2014-06-05T20:56:12Z					biological_process											owl:Class	
GO:0102861	biolink:NamedThing	1-18:2-2-18:1-phosphatidylcholine desaturase activity (SN2-18:2 forming)	Catalysis of the reaction: 1-18:2-2-18:1-phosphatidylcholine + O2 + a reduced electron acceptor = 1-18:2-2-18:2-sn-glycerol-3-phosphocholine + 2 H2O + an oxidized electron acceptor.	tmpzr1t_l9r_go_relaxed.owl					EC:1.14.19.22|MetaCyc:RXN-8328									molecular_function											owl:Class	
GO:0018972	biolink:NamedThing	toluene-4-sulfonate metabolic process	The chemical reactions and pathways involving toluene-4-sulfonate, the anion of 4-toluene sulfonic acid, a white crystalline solid which is highly hygroscopic and soluble in water.	tmpzr1t_l9r_go_relaxed.owl	toluene-4-sulphonate metabolic process|toluene-4-sulphonate metabolism|4-methylbenzenesulfonate metabolism|toluene-4-sulfonate metabolism|4-toluenesulfonate metabolism|4-toluenesulfonate metabolic process|4-methylbenzenesulfonate metabolic process				UM-BBD_pathwayID:tsa|MetaCyc:TOLSULFDEG-PWY									biological_process											owl:Class	
GO:0106058	biolink:NamedThing	positive regulation of calcineurin-mediated signaling	Any process that activates or increases the frequency, rate or extent of calcineurin-mediated signaling.	tmpzr1t_l9r_go_relaxed.owl								hjd	2017-09-18T16:57:06Z					biological_process											owl:Class	
GO:0046563	biolink:NamedThing	methanol oxidase activity	Catalysis of the reaction: O2 + methanol = H2O2 + formaldehyde.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:METHANOL-OXIDASE-RXN|EC:1.1.3.-	Note that EC:1.1.3.31 was deleted from EC as it cannot be distinguished from alcohol oxidase (EC:1.1.3.13).								molecular_function											owl:Class	
GO:0075510	biolink:NamedThing	macropinocytosis involved in viral entry into host cell	Any macropinocytosis that is involved in the uptake of a virus into a host cell.	tmpzr1t_l9r_go_relaxed.owl	viral entry into host cell via macropinocytosis				VZ:800			jl	2011-07-27T11:24:59Z					biological_process											owl:Class	
GO:0047849	biolink:NamedThing	dextransucrase activity	Catalysis of the reaction: sucrose + 1,6-alpha-D-glucosyl(n) = D-fructose + 1,6-alpha-D-glucosyl(n+1).	tmpzr1t_l9r_go_relaxed.owl	CEP|sucrose 6-glucosyltransferase activity|SGE|sucrose-1,6-alpha-glucan glucosyltransferase activity|sucrose:1,6-alpha-D-glucan 6-alpha-D-glucosyltransferase activity				MetaCyc:DEXTRANSUCRASE-RXN|EC:2.4.1.5									molecular_function											owl:Class	
GO:0004778	biolink:NamedThing	succinyl-CoA hydrolase activity	Catalysis of the reaction: H(2)O + succinyl-CoA = CoA + H(+) + succinate.	tmpzr1t_l9r_go_relaxed.owl	succinyl coenzyme A deacylase activity|succinyl coenzyme A hydrolase activity|succinyl-CoA acylase activity				MetaCyc:SUCCINYL-COA-HYDROLASE-RXN|RHEA:11516|EC:3.1.2.3|KEGG_REACTION:R00407									molecular_function											owl:Class	
GO:0040040	biolink:NamedThing	thermosensory behavior	Behavior that is dependent upon the sensation of temperature.	tmpzr1t_l9r_go_relaxed.owl	thermosensory behaviour|behavioral response to temperature stimulus|behavioural response to temperature stimulus													biological_process											owl:Class	
GO:0001917	biolink:NamedThing	photoreceptor inner segment	The inner segment of a vertebrate photoreceptor containing mitochondria, ribosomes and membranes where opsin molecules are assembled and passed to be part of the outer segment discs.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0050156	biolink:NamedThing	ornithine N-benzoyltransferase activity	Catalysis of the reaction: L-ornithine + 2 benzoyl-CoA = N(2),N(5)-dibenzoyl-L-ornithine + 2 CoA + 2 H(+).	tmpzr1t_l9r_go_relaxed.owl	benzoyl-CoA:L-ornithine N-benzoyltransferase activity|ornithine N-acyltransferase activity				EC:2.3.1.127|KEGG_REACTION:R00664|RHEA:16929|MetaCyc:ORNITHINE-N-BENZOYLTRANSFERASE-RXN									molecular_function											owl:Class	
GO:0047847	biolink:NamedThing	deoxyuridine phosphorylase activity	Catalysis of the reaction: deoxyuridine + phosphate = uracil + deoxy-D-ribose 1-phosphate.	tmpzr1t_l9r_go_relaxed.owl	2'-deoxyuridine:phosphate 2-deoxy-alpha-D-ribosyltransferase activity|deoxyuridine:phosphate deoxy-D-ribosyltransferase activity|deoxyuridine:phosphate deoxy-alpha-D-ribosyltransferase activity				EC:2.4.2.23|MetaCyc:DEOXYURIDINE-PHOSPHORYLASE-RXN|RHEA:22824									molecular_function											owl:Class	
GO:0046892	biolink:NamedThing	peptidyl-S-carbamoyl-L-cysteine dehydration	The dehydration of peptidyl-S-carbamoyl-L-cysteine to form peptidyl-S-cyano-L-cysteine.	tmpzr1t_l9r_go_relaxed.owl	formation of peptidyl-serine thiocyanate ester|formation of peptidyl-S-cyanocysteine				RESID:AA0333									biological_process											owl:Class	
GO:0006676	biolink:NamedThing	mannosyl diphosphorylinositol ceramide metabolic process	The chemical reactions and pathways involving mannosyl diphosphorylinositol ceramide, any lipid with a phosphodiester bridge between an inositol residue and the ceramide group which contains two phosphoryl (-P(O)=) groups and a mannose derivative.	tmpzr1t_l9r_go_relaxed.owl	M(IP)2C metabolism|M(IP)2C metabolic process|mannosyl diphosphorylinositol ceramide metabolism													biological_process											owl:Class	
GO:0000315	biolink:NamedThing	organellar large ribosomal subunit	The larger of the two subunits of an organellar ribosome. Two sites on the ribosomal large subunit are involved in translation: the aminoacyl site (A site) and peptidyl site (P site).	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0010424	biolink:NamedThing	DNA methylation on cytosine within a CG sequence	The covalent transfer of a methyl group to C-5 or N-4 of a cytosine located within a CG sequence in a DNA molecule.	tmpzr1t_l9r_go_relaxed.owl	cytosine methylation within a CG sequence													biological_process											owl:Class	
GO:0102931	biolink:NamedThing	(Z,E)-alpha- farnesene synthase activity	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = (Z,E)-alpha-farnesene + diphosphoric acid.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-8931									molecular_function											owl:Class	
GO:0050469	biolink:NamedThing	sabinene-hydrate synthase activity	Catalysis of the reaction: geranyl diphosphate + H(2)O = diphosphate + sabinene hydrate.	tmpzr1t_l9r_go_relaxed.owl	sabinene hydrate cyclase activity|geranyl-diphosphate diphosphate-lyase (cyclizing, sabinene-hydrate-forming)				KEGG_REACTION:R02006|MetaCyc:4.2.3.11-RXN|EC:4.2.3.11|RHEA:19565									molecular_function											owl:Class	
GO:0008791	biolink:NamedThing	arginine N-succinyltransferase activity	Catalysis of the reaction: succinyl-CoA + L-arginine = CoA + N2-succinyl-L-arginine.	tmpzr1t_l9r_go_relaxed.owl	arginine and ornithine N(2)-succinyltransferase activity|arginine and ornithine N2-succinyltransferase activity|AST activity|AstA|arginine succinyltransferase activity|succinyl-CoA:L-arginine 2-N-succinyltransferase activity|succinyl-CoA:L-arginine N2-succinyltransferase activity|AOST activity				EC:2.3.1.109|MetaCyc:ARGININE-N-SUCCINYLTRANSFERASE-RXN|RHEA:15185									molecular_function											owl:Class	
GO:0042380	biolink:NamedThing	hydroxymethylbutenyl pyrophosphate reductase activity	Catalysis of the formation of both isopentenyl pyrophosphate and dimethylallyl pyrophosphate from (E)-4-hydroxy-3-methyl-but-2-enyl pyrophosphate.	tmpzr1t_l9r_go_relaxed.owl	(E)-4-hydroxy-3-methyl-but-2-enyl pyrophosphate reductase (IPP and DMAPP forming)													molecular_function											owl:Class	
GO:0060023	biolink:NamedThing	soft palate development	The biological process whose specific outcome is the progression of the soft palate from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. The soft palate is the posterior portion of the palate extending from the posterior edge of the hard palate.	tmpzr1t_l9r_go_relaxed.owl	palatum molle development|velum palatum development													biological_process											owl:Class	
GO:1900275	biolink:NamedThing	negative regulation of phospholipase C activity	Any process that stops, prevents or reduces the frequency, rate or extent of phospholipase C activity.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of lecithinase C activity|down-regulation of lecithinase C activity|inhibition of phospholipase C activity|downregulation of lipophosphodiesterase C|down-regulation of phosphatidase C|downregulation of phospholipase C activity|negative regulation of lipophosphodiesterase C|downregulation of lecithinase C activity|inhibition of phosphatidase C|down-regulation of lipophosphodiesterase C|negative regulation of phosphatidase C|downregulation of phosphatidase C|down-regulation of phospholipase C activity|inhibition of lecithinase C activity|down regulation of phosphatidase C|down regulation of lecithinase C activity|inhibition of lipophosphodiesterase C|down regulation of phospholipase C activity|down regulation of lipophosphodiesterase C							rl	2012-04-04T01:19:10Z					biological_process											owl:Class	
GO:0050635	biolink:NamedThing	acridone synthase activity	Catalysis of the reaction: N-methylanthranilyl-CoA + 3 H(+) + 3 malonyl-CoA = 1,3-dihydroxy-N-methylacridone + 3 CO(2) + 4 CoA + H(2)O.	tmpzr1t_l9r_go_relaxed.owl	malonyl-CoA:N-methylanthraniloyl-CoA malonyltransferase (cyclizing)				KEGG_REACTION:R07250|EC:2.3.1.159|RHEA:22224|MetaCyc:2.3.1.159-RXN									molecular_function											owl:Class	
GO:0034683	biolink:NamedThing	integrin alphav-beta3 complex	An integrin complex that comprises one alphav subunit and one beta3 subunit.	tmpzr1t_l9r_go_relaxed.owl	alphav-beta3 integrin complex|ITGAV-ITGB3 complex													cellular_component											owl:Class	
GO:0036339	biolink:NamedThing	lymphocyte adhesion to endothelial cell of high endothelial venule	The attachment of a lymphocyte to an endothelial cell of a high endothelial venule (HEV) via adhesion molecules. A HEV cell is an endothelial cell that is cuboidal, expresses leukocyte-specific receptors, and allows for passage of lymphocytes into bloodstream.	tmpzr1t_l9r_go_relaxed.owl	lymphocyte adhesion to HEV cell|lymphocyte adhesion to high endothelial venule					For the transition of leukocytes from rolling to adhered, consider instead annotating to 'leukocyte adhesive activation ; GO:0050902'.		bf	2012-09-10T16:00:23Z					biological_process											owl:Class	
GO:0047646	biolink:NamedThing	alkanal monooxygenase (FMN-linked) activity	Catalysis of the reaction: R-CHO + reduced FMN + O2 = R-COOH + FMN + H2O + light.	tmpzr1t_l9r_go_relaxed.owl	alkanal,reduced-FMN:oxygen oxidoreductase (1-hydroxylating, luminescing)|bacterial luciferase activity|aldehyde monooxygenase activity|vibrio fischeri luciferase activity				RHEA:17181|EC:1.14.14.3|MetaCyc:ALKANAL-MONOOXYGENASE-FMN-LINKED-RXN									molecular_function											owl:Class	
GO:0110093	biolink:NamedThing	nucleus lagging edge	The area of a motile nucleus furthest from the direction of movement.	tmpzr1t_l9r_go_relaxed.owl								kmv	2018-02-14T22:56:12Z					cellular_component											owl:Class	
GO:0035380	biolink:NamedThing	very long-chain-3-hydroxyacyl-CoA dehydrogenase activity	Catalysis of the reaction: (S)-3-hydroxyacyl-CoA + NAD(P)+ = 3-oxoacyl-CoA + NAD(P)H + H+, where the acyl group is a very long-chain fatty acid residue. A very long-chain fatty acid is a fatty acid which has a chain length greater than C22.	tmpzr1t_l9r_go_relaxed.owl	very-long-chain-3-hydroxyacyl-CoA dehydrogenase activity							bf	2010-03-18T11:23:05Z					molecular_function											owl:Class	
GO:1990265	biolink:NamedThing	platelet-derived growth factor complex	A protein complex consisting of two chains of platelet-derived growth factor (PDGF) subunits. PDGF dimers bind to PDGF receptors in the plasma membrane and induce receptor dimerisation and activation. PDGFs are involved in a wide variety of signalling processes. PDGFs are found in all vertebrates where at least 2 different chains (A and B) exist. In human (and other mammals), four types of PDGF chains (A, B, C, and D) are known which form five different dimers (AA, AB, BB, CC and DD).	tmpzr1t_l9r_go_relaxed.owl	PDGF-BB dimer|PDGF-CC dimer|PDGF-AB dimer|PDGF-AA dimer|PDGF complex|PDGF-DD dimer					An example of this is PDGFA in human (P04085) in PMID:20534510 (inferred from direct assay).		bhm	2014-01-09T16:09:11Z					cellular_component											owl:Class	
GO:0046490	biolink:NamedThing	isopentenyl diphosphate metabolic process	The chemical reactions and pathways involving isopentenyl diphosphate, an isomer of dimethylallyl diphosphate and the key precursor of all isoprenoids.	tmpzr1t_l9r_go_relaxed.owl	IPP metabolism|isopentenyl diphosphate metabolism|IPP metabolic process|isopentenyl pyrophosphate metabolism|isopentenyl pyrophosphate metabolic process													biological_process											owl:Class	
GO:0060074	biolink:NamedThing	synapse maturation	The process that organizes a synapse so that it attains its fully functional state. Synaptic maturation plays a critical role in the establishment of effective synaptic connections in early development.	tmpzr1t_l9r_go_relaxed.owl	synaptic maturation													biological_process											owl:Class	
GO:0106142	biolink:NamedThing	rRNA (adenine-N1-)-methyltransferase activity	Catalysis of the reaction:  S-adenosyl-L-methionine + adenine(645) in 25S rRNA = S-adenosyl-L-homocysteine + N(1)-methyladenine(645) in 25S rRNA.	tmpzr1t_l9r_go_relaxed.owl	25S rRNA (adenine(645)-N(1))-methyltransferase|25S rRNA m(1)A(645) methyltransferase				RHEA:43792|EC:2.1.1.287	The m(1)A modification at position 645 in the large rRNA is highly conserved in eukaryotes.		hjd	2018-08-22T20:13:21Z					molecular_function											owl:Class	
GO:0007425	biolink:NamedThing	epithelial cell fate determination, open tracheal system	The cell fate determination process in which a cell becomes capable of differentiating autonomously into an epithelial cell within an open tracheal system regardless of its environment; upon determination, the cell fate cannot be reversed. Tracheal cells are set aside as 10 clusters of approximately 80 cells on each side of the embryo (termed tracheal placodes). An example of this is found in Drosophila melanogaster.	tmpzr1t_l9r_go_relaxed.owl	tracheal cell fate determination|tracheal epithelial cell fate determination|tracheal placode cell fate determination											GO:0046846		biological_process											owl:Class	
GO:0000825	biolink:NamedThing	inositol tetrakisphosphate 6-kinase activity	Catalysis of the reaction: 1D-myo-inositol 1,3,4,5-tetrakisphosphate + ATP = 1D-myo-inositol 1,3,4,5,6-pentakisphosphate + ADP.	tmpzr1t_l9r_go_relaxed.owl	inositol 1,3,4,5-tetrakisphosphate 6-kinase activity|1D-myo-inositol-tetrakisphosphate 6-kinase activity				Reactome:R-HSA-1855206|MetaCyc:RXN-7184									molecular_function											owl:Class	
GO:1990641	biolink:NamedThing	response to iron ion starvation	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of iron ion.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-02-11T18:43:28Z					biological_process											owl:Class	
GO:0102475	biolink:NamedThing	2-hydroxyeriodictyol 6C-glucoside dehydratase activity	Catalysis of the reaction: 6C-beta-D-glucosyl-2-hydroxyeriodictyol <=> isoorientin + H2O.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-14081									molecular_function											owl:Class	
GO:0061408	biolink:NamedThing	positive regulation of transcription from RNA polymerase II promoter in response to heat stress	Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.	tmpzr1t_l9r_go_relaxed.owl								dph	2012-01-12T11:50:30Z					biological_process											owl:Class	
GO:1990435	biolink:NamedThing	upper tip-link density	An electron-dense plaque at the upper end of a stereocilia tip link that provides the anchor in the stereocilia membrane on the side of the stereocilium where the tip link ends.	tmpzr1t_l9r_go_relaxed.owl	UTLD							sl	2014-07-30T16:36:32Z					cellular_component											owl:Class	
GO:1902091	biolink:NamedThing	negative regulation of fumagillin biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of fumagillin biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	downregulation of fumagillin formation|down-regulation of fumagillin synthesis|downregulation of fumagillin biosynthesis|down regulation of fumagillin biosynthesis|inhibition of fumagillin formation|down-regulation of fumagillin biosynthetic process|downregulation of fumagillin synthesis|downregulation of fumagillin biosynthetic process|down-regulation of fumagillin anabolism|down regulation of fumagillin formation|negative regulation of fumagillin anabolism|down-regulation of fumagillin formation|inhibition of fumagillin biosynthesis|inhibition of fumagillin biosynthetic process|negative regulation of fumagillin biosynthesis|down regulation of fumagillin synthesis|negative regulation of fumagillin synthesis|inhibition of fumagillin anabolism|inhibition of fumagillin synthesis|downregulation of fumagillin anabolism|negative regulation of fumagillin formation|down regulation of fumagillin anabolism|down-regulation of fumagillin biosynthesis|down regulation of fumagillin biosynthetic process							di	2013-04-27T03:45:04Z					biological_process											owl:Class	
GO:0070834	biolink:NamedThing	phosphatidylcholine biosynthesis from phosphoryl-ethanolamine via N-dimethylethanolamine phosphate and CDP-N-dimethylethanolamine	The phosphatidylcholine biosynthetic process that begins with two N-methylations with phospho-base phosphoethanolamine and phospho-N-methylethanolamine, followed by a downstream N-methylation on phosphatidyl-base phosphatidyl-N-dimethylethanolamine; the process ends with the conversion of a phosphatidyl-N-dimethylethanolamine to a phosphatidylcholine.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:PWY4FS-4			mah	2009-07-29T03:54:47Z					biological_process											owl:Class	
GO:0071906	biolink:NamedThing	CRD domain binding	Binding to a CRD (context dependent regulatory) domain, a domain of about 130 residues that is the most divergent region among the LEF/TCF proteins.	tmpzr1t_l9r_go_relaxed.owl	context dependent regulatory domain binding							mah	2010-09-21T04:08:53Z					molecular_function											owl:Class	
GO:0052913	biolink:NamedThing	16S rRNA (guanine(966)-N(2))-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + guanosine(966) in 16S rRNA = N(2)-methylguanosine(966) in 16S rRNA + S-adenosyl-L-homocysteine.	tmpzr1t_l9r_go_relaxed.owl					EC:2.1.1.171|RHEA:23548|KEGG_REACTION:R07234|MetaCyc:RXN0-6515									molecular_function											owl:Class	
GO:0050073	biolink:NamedThing	macrolide 2'-kinase activity	Catalysis of the reaction: ATP + oleandomycin = ADP + 2 H(+) + oleandomycin 2'-O-phosphate.	tmpzr1t_l9r_go_relaxed.owl	ATP:macrolide 2'-O-phosphotransferase activity				EC:2.7.1.136|KEGG_REACTION:R03780|MetaCyc:MACROLIDE-2-KINASE-RXN|RHEA:18333									molecular_function											owl:Class	
GO:1990465	biolink:NamedThing	aldehyde oxygenase (deformylating) activity	Catalysis of the reaction a long-chain aldehyde + O(2) + 2 NADPH = an alkane + formate + H(2)O + 2 NADP(+).	tmpzr1t_l9r_go_relaxed.owl					EC:4.1.99.5|RHEA:21440			tt	2014-08-25T15:16:43Z					molecular_function											owl:Class	
GO:0070023	biolink:NamedThing	interleukin-12-interleukin-12 receptor complex	A protein complex that is formed by the association of a heterodimeric interleukin-12 receptor complex with an interleukin-12 heterodimer.	tmpzr1t_l9r_go_relaxed.owl	IL12B-IL12RB1-IL12RB2 complex|IL12-IL12 receptor complex													cellular_component											owl:Class	
GO:0102064	biolink:NamedThing	gamma-curcumene synthase activity	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate <=> gamma-curcumene + diphosphoric acid.	tmpzr1t_l9r_go_relaxed.owl					EC:4.2.3.94|MetaCyc:RXN-10599|RHEA:32031									molecular_function											owl:Class	
GO:1905308	biolink:NamedThing	cellular response to miconazole	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a miconazole stimulus.	tmpzr1t_l9r_go_relaxed.owl								al	2016-07-06T11:55:30Z					biological_process											owl:Class	
GO:0034396	biolink:NamedThing	negative regulation of transcription from RNA polymerase II promoter in response to iron	Any process that stops, prevents or reduces the rate of transcription from an RNA polymerase II promoter in response to an iron stimulus.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of transcription from Pol II promoter in response to iron|down regulation of transcription from RNA polymerase II promoter in response to iron|inhibition of transcription from RNA polymerase II promoter in response to iron|downregulation of transcription from RNA polymerase II promoter in response to iron|down-regulation of transcription from RNA polymerase II promoter in response to iron													biological_process											owl:Class	
GO:0033466	biolink:NamedThing	trans-zeatin biosynthetic process	The chemical reactions and pathways resulting in the formation of trans-zeatin, (2E)-2-methyl-4-(9H-purin-6-ylamino)but-2-en-1-ol.	tmpzr1t_l9r_go_relaxed.owl	trans-zeatin anabolism|trans-zeatin synthesis|trans-zeatin biosynthesis|trans-zeatin formation				MetaCyc:PWY-2681									biological_process											owl:Class	
GO:0090537	biolink:NamedThing	CERF complex	An ISWI complex that contains an ATPase subunit of the ISWI family (specifically SNF2L in mammals, which contain two ISWI homologs) and a CECR2 homolog. In mammals, CERF is involved in regulation of transcription from RNA polymerase II promoters.	tmpzr1t_l9r_go_relaxed.owl								tb	2013-02-11T14:07:14Z					cellular_component											owl:Class	
GO:0036020	biolink:NamedThing	endolysosome membrane	The lipid bilayer surrounding an endolysosome. An endolysosome is a transient hybrid organelle formed by fusion of a late endosome with a lysosome.	tmpzr1t_l9r_go_relaxed.owl	endolysosomal membrane							bf	2011-10-13T04:32:00Z					cellular_component											owl:Class	
GO:0036488	biolink:NamedThing	CHOP-C/EBP complex	A heterodimeric protein complex that is composed of the transcription factor CHOP (GADD153) and a member of the C/EBP family of transcription factors.	tmpzr1t_l9r_go_relaxed.owl	GADD153-C/EBP-alpha complex|CHOP-C/EBP dimer|GADD153-C/EBP complex|CHOP-C/EBP heterodimer							bf	2014-11-06T13:18:49Z					cellular_component											owl:Class	
GO:0033358	biolink:NamedThing	UDP-L-arabinose biosynthetic process	The chemical reactions and pathways resulting in the formation of UDP-L-arabinose, uridinediphosphoarabinose, a substance composed of arabinose in glycosidic linkage with uridine diphosphate.	tmpzr1t_l9r_go_relaxed.owl	UDP-L-arabinose formation|UDP-L-arabinose biosynthesis|UDP-L-arabinose synthesis|UDP-L-arabinose anabolism				MetaCyc:PWY-82|MetaCyc:PWY-63									biological_process											owl:Class	
GO:0002277	biolink:NamedThing	myeloid dendritic cell activation involved in immune response	The change in morphology and behavior of a myeloid dendritic cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response.	tmpzr1t_l9r_go_relaxed.owl	myeloid dendritic cell activation during immune response													biological_process											owl:Class	
GO:0030746	biolink:NamedThing	isoflavone 4'-O-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + isoflavone = S-adenosyl-L-homocysteine + 4'-O-methylisoflavone.	tmpzr1t_l9r_go_relaxed.owl	4'-hydroxyisoflavone methyltransferase activity|S-adenosyl-L-methionine:isoflavone 4'-O-methyltransferase activity|isoflavone O-methyltransferase activity|isoflavone methyltransferase activity				MetaCyc:ISOFLAVONE-4-O-METHYLTRANSFERASE-RXN|RHEA:31739|EC:2.1.1.46									molecular_function											owl:Class	
GO:0061040	biolink:NamedThing	female gonad morphogenesis	The process in which a female gonad is generated and organized.	tmpzr1t_l9r_go_relaxed.owl	ovary morphogenesis							dph	2010-02-22T11:29:28Z					biological_process											owl:Class	
GO:0043811	biolink:NamedThing	phosphate:acyl-[acyl carrier protein] acyltransferase activity	Catalysis of the reaction: acyl-[acyl-carrier protein] + orthophosphate = acyl phosphate + [acyl-carrier protein].	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0045246	biolink:NamedThing	cytosolic tricarboxylic acid cycle enzyme complex	Any of the heteromeric enzymes, located in the cytosol, that act in the tricarboxylic acid (TCA) cycle.	tmpzr1t_l9r_go_relaxed.owl	tricarboxylic acid cycle enzyme complex|TCA cycle enzyme complex													cellular_component											owl:Class	
GO:0014716	biolink:NamedThing	skeletal muscle satellite stem cell asymmetric division involved in skeletal muscle regeneration	Skeletal muscle satellite cell asymmetric division that occurs during a process in which damaged muscle tissue is being rebuilt.	tmpzr1t_l9r_go_relaxed.owl	satellite cell asymmetric division involved in skeletal muscle regeneration					Occurrence of this process outside of the context of muscle repair is probably very rare, so there is a good case for merging this with the parent class.								biological_process											owl:Class	
GO:0086077	biolink:NamedThing	gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling	A wide pore channel activity that enables a direct cytoplasmic connection from an AV node cell to a bundle of His cell. The gap junction passes electrical signals between the cells contributing to cardiac conduction.	tmpzr1t_l9r_go_relaxed.owl	gap junction channel activity involved in atrioventricular node cell-bundle of His cell electrical coupling							dph	2011-11-22T10:29:53Z					molecular_function											owl:Class	
GO:0021914	biolink:NamedThing	negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning	Any process that stops, prevents, or reduces the frequency, rate or extent of smoothened signaling that is involved in the patterns of cell differentiation in the ventral spinal cord.	tmpzr1t_l9r_go_relaxed.owl	inhibition of smoothened signaling pathway in ventral spinal cord patterning|down-regulation of smoothened signaling pathway in ventral spinal cord patterning|negative regulation of hedgehog signaling pathway involved in ventral spinal cord patterning|negative regulation of hh signaling pathway involved in ventral spinal cord patterning|down regulation of smoothened signaling pathway in ventral spinal cord patterning|downregulation of smoothened signaling pathway in ventral spinal cord patterning|negative regulation of smoothened signalling pathway in ventral spinal cord patterning													biological_process											owl:Class	
GO:1903492	biolink:NamedThing	response to acetylsalicylate	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an aspirin (acetylsalicylate) stimulus. Aspirin is a non-steroidal anti-inflammatory drug with moA cyclooxygenase inhibitor activity.	tmpzr1t_l9r_go_relaxed.owl								hp	2014-09-25T10:58:23Z					biological_process											owl:Class	
GO:0043444	biolink:NamedThing	acetone catabolic process	The chemical reactions and pathways resulting in the breakdown of acetone, propan-2-one.	tmpzr1t_l9r_go_relaxed.owl	2-propanone catabolic process|acetone degradation|2-propanone catabolism|dimethyl ketone catabolic process|acetone catabolism|propan-2-one catabolism|propan-2-one catabolic process|dimethyl ketone catabolism|acetone breakdown													biological_process											owl:Class	
GO:1902857	biolink:NamedThing	positive regulation of non-motile cilium assembly	Any process that activates or increases the frequency, rate or extent of non-motile cilium assembly.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of nonmotile primary cilium assembly|activation of sensory cilium assembly|up regulation of sensory cilium assembly|upregulation of nonmotile primary cilia assembly|positive regulation of nonmotile primary cilium assembly|upregulation of sensory cilium biogenesis|positive regulation of immotile primary cilium assembly|up regulation of sensory cilium biogenesis|up regulation of nonmotile primary cilia assembly|activation of immotile primary cilium assembly|positive regulation of sensory cilium biogenesis|upregulation of immotile primary cilium assembly|up regulation of immotile primary cilium assembly|positive regulation of nonmotile primary cilia assembly|activation of nonmotile primary cilia assembly|activation of nonmotile primary cilium assembly|up regulation of nonmotile primary cilium assembly|upregulation of nonmotile primary cilium assembly|upregulation of sensory cilium assembly|up-regulation of immotile primary cilium assembly|activation of sensory cilium biogenesis|up-regulation of sensory cilium biogenesis|up-regulation of nonmotile primary cilia assembly|up-regulation of sensory cilium assembly|positive regulation of sensory cilium assembly							kmv	2014-04-02T15:42:31Z					biological_process											owl:Class	
GO:1990079	biolink:NamedThing	cartilage homeostasis	A tissue homeostatic process involved in the maintenance of an internal equilibrium within cartilage, including control of cellular proliferation and death and control of metabolic function.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of cartilage homeostasis|positive regulation of cartilage homeostasis|regulation of cartilage homeostasis							hjd	2013-04-29T20:10:15Z			GO:1902094|GO:1902095|GO:1902096		biological_process											owl:Class	
GO:0009879	biolink:NamedThing	determination of radial symmetry	The establishment of an organism's body plan or a part of an organism such that it is symmetric around a central axis.	tmpzr1t_l9r_go_relaxed.owl	determination of radial asymmetry													biological_process											owl:Class	
GO:0036085	biolink:NamedThing	GDP-fucose import into Golgi lumen	The directed movement of GDP-fucose into the Golgi lumen. GDP-fucose is a substance composed of fucose in glycosidic linkage with guanosine diphosphate.	tmpzr1t_l9r_go_relaxed.owl	GDP-fucose transport into Golgi lumen|GDP-fucose transport across Golgi membrane|GDP-fucose import into Golgi							bf	2011-12-21T01:52:10Z					biological_process											owl:Class	
GO:0015783	biolink:NamedThing	GDP-fucose transmembrane transport	The directed movement of GDP-fucose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GDP-fucose is a substance composed of fucose in glycosidic linkage with guanosine diphosphate.	tmpzr1t_l9r_go_relaxed.owl	GDP-fucose transport													biological_process											owl:Class	
GO:0038123	biolink:NamedThing	toll-like receptor TLR1:TLR2 signaling pathway	A series of molecular signals initiated by the binding of a heterodimeric TLR1:TLR2 complex to one of it's physiological ligands, followed by transmission of the signal by the activated receptor, and ending with regulation of a downstream cellular process, e.g. transcription.	tmpzr1t_l9r_go_relaxed.owl	toll-like receptor TLR1:TLR2 signalling pathway|TLR2:TLR1 signaling pathway							bf	2012-03-23T10:20:13Z					biological_process											owl:Class	
GO:1901116	biolink:NamedThing	cephamycin C metabolic process	The chemical reactions and pathways involving cephamycin C.	tmpzr1t_l9r_go_relaxed.owl	cephamycin C metabolism							yaf	2012-07-11T03:06:51Z					biological_process											owl:Class	
GO:0045711	biolink:NamedThing	positive regulation of adult salivary gland boundary specification	Any process that activates or increases the frequency, rate or extent of salivary gland determination in an adult organism.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of adult salivary gland determination|upregulation of adult salivary gland determination|up regulation of adult salivary gland determination|stimulation of adult salivary gland determination|positive regulation of adult salivary gland determination|activation of adult salivary gland determination													biological_process											owl:Class	
GO:0018406	biolink:NamedThing	protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan	The glycosylation of a peptidyl-tryptophan residue by the transfer of alpha-mannopyranose from dolichyl-activated mannose to the indole ring.	tmpzr1t_l9r_go_relaxed.owl	protein amino acid C-linked mannosylation|protein amino acid C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan				RESID:AA0217							GO:0032004		biological_process											owl:Class	
GO:0018317	biolink:NamedThing	protein C-linked glycosylation via tryptophan	The glycosylation of a carbon atom of a peptidyl-tryptophan residue.	tmpzr1t_l9r_go_relaxed.owl	protein amino acid C-linked glycosylation via tryptophan													biological_process											owl:Class	
GO:0031719	biolink:NamedThing	type 2 cannabinoid receptor binding	Binding to a type 2 cannabinoid receptor.	tmpzr1t_l9r_go_relaxed.owl	type 2 cannabinoid receptor ligand													molecular_function											owl:Class	
GO:0031717	biolink:NamedThing	cannabinoid receptor binding	Binding to a cannabinoid receptor.	tmpzr1t_l9r_go_relaxed.owl	cannabinoid receptor ligand													molecular_function											owl:Class	
GO:0034828	biolink:NamedThing	4-(2-oxocyclohexyl)-2-hydroxy-buta-2,4-dienoate hydrolase activity	Catalysis of the reaction: 4-(2-oxocyclohexyl)-2-hydroxy-buta-2,4-dienoate + H2O = 2-hydroxydec-2,4-diene-1,10-dioate + H+.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r1172									molecular_function											owl:Class	
GO:0102148	biolink:NamedThing	N-acetyl-beta-D-galactosaminidase activity	Catalysis of the reaction: H2O + an N-acetyl-beta-D-galactosalaminyl-[glycan] = N-acetyl-beta-D-galactosamine + a glycan.	tmpzr1t_l9r_go_relaxed.owl					EC:3.2.1.52|MetaCyc:RXN-11622									molecular_function											owl:Class	
GO:0042904	biolink:NamedThing	9-cis-retinoic acid biosynthetic process	The chemical reactions and pathways resulting in the formation of 9-cis-retinoic acid, a metabolically active vitamin A derivative.	tmpzr1t_l9r_go_relaxed.owl	9-cis-retinoic acid formation|9-cis-retinoic acid synthesis|9-cis-retinoic acid anabolism|9-cis-retinoic acid biosynthesis													biological_process											owl:Class	
GO:0005519	biolink:NamedThing	cytoskeletal regulatory protein binding	Binding to a protein involved in modulating the reorganization of the cytoskeleton.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0098514	biolink:NamedThing	detection of high humidity stimulus involved in sensory perception	The series of events in which a high humidity stimulus is detected and converted into a molecular signal as a part of the sensory detection of high humidity.	tmpzr1t_l9r_go_relaxed.owl								dos	2013-09-25T14:20:54Z					biological_process											owl:Class	
GO:0060235	biolink:NamedThing	lens induction in camera-type eye	Signaling at short range between the head ectoderm and the optic vesicle that results in the head ectoderm forming a lens.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0102457	biolink:NamedThing	cyanidin 3-O-glucoside 7-O-glucosyltransferase (vanilloyl-glucose dependent) activity	Catalysis of the reaction: cyanidin 3-O-beta-D-glucoside betaine + 1-O-vanilloyl-beta-D-glucose <=> H+ + cyanidin 3,7-di-O-beta-D-glucoside betaine + vanillate.	tmpzr1t_l9r_go_relaxed.owl					EC:2.4.1.300|RHEA:35431|MetaCyc:RXN-13969									molecular_function											owl:Class	
GO:1990965	biolink:NamedThing	cytosylglucuronate decarboxylase activity	Catalysis of the reaction: cytosylglucuronic acid + H(+) = cytosylarabinopyranose + CO(2).	tmpzr1t_l9r_go_relaxed.owl						This enzymatic activity was shown to be involved in the bacterial blasticidin S biosynthetic pathway.		pr	2016-06-09T13:05:27Z					molecular_function											owl:Class	
GO:0051670	biolink:NamedThing	inulinase activity	Catalysis of the endohydrolysis of 2,1-beta-D-fructosidic linkages in inulin.	tmpzr1t_l9r_go_relaxed.owl	indoinulinase activity|endo-inulinase activity|exoinulinase activity|inulase activity|2,1-beta-D-fructan fructanohydrolase activity				MetaCyc:3.2.1.7-RXN|EC:3.2.1.7									molecular_function											owl:Class	
GO:0032047	biolink:NamedThing	mitosome	A double-membrane-bounded organelle that functions in iron-sulfur protein maturation; evolutionarily derived from mitochondria. The mitosome has been detected only in anaerobic or microaerophilic organisms that do not have mitochondria, such as Entamoeba histolytica, Giardia intestinalis and several species of Microsporidia. These organisms are not capable of gaining energy from oxidative phosphorylation, which is normally performed by mitochondria.	tmpzr1t_l9r_go_relaxed.owl	crypton				Wikipedia:Mitosome	In Giardia species, mitosomes are sometimes present between the two nuclei.								cellular_component											owl:Class	
GO:0070995	biolink:NamedThing	NADPH oxidation	A metabolic process that results in the oxidation of reduced nicotinamide adenine dinucleotide, NADPH, to the oxidized form, NADP.	tmpzr1t_l9r_go_relaxed.owl	reduced nicotinamide adenine dinucleotide phosphate dehydrogenation|NADP (reduced) oxidation|NADP (reduced) dehydrogenation|reduced NADP oxidation|reduced nicotinamide adenine dinucleotide phosphate oxidation|NADPH dehydrogenation|reduced NADP dehydrogenation							mah	2009-11-03T12:02:15Z					biological_process											owl:Class	
GO:0061990	biolink:NamedThing	beta-ketodecanoyl-[acyl-carrier-protein] synthase activity	Catalysis of the reaction: octanoyl-CoA + a malonyl-[acyl-carrier protein] = a 3-oxodecanoyl-[acyl-carrier protein] + CoA + CO2.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-13613|RHEA:42264			dph	2018-02-15T22:29:03Z					molecular_function											owl:Class	
GO:0090023	biolink:NamedThing	positive regulation of neutrophil chemotaxis	Any process that increases the frequency, rate, or extent of neutrophil chemotaxis. Neutrophil chemotaxis is the directed movement of a neutrophil cell, the most numerous polymorphonuclear leukocyte found in the blood, in response to an external stimulus, usually an infection or wounding.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-08-03T10:12:23Z					biological_process											owl:Class	
GO:0016732	biolink:NamedThing	oxidoreductase activity, acting on iron-sulfur proteins as donors, dinitrogen as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which an iron-sulfur protein acts as a hydrogen or electron donor and reduces dinitrogen.	tmpzr1t_l9r_go_relaxed.owl					EC:1.18.6.-									molecular_function											owl:Class	
GO:1990544	biolink:NamedThing	mitochondrial ATP transmembrane transport	The process in which ATP is transported across a mitochondrial membrane, into or out of the mitochondrion.	tmpzr1t_l9r_go_relaxed.owl								vw	2014-11-19T11:43:33Z					biological_process											owl:Class	
GO:0002187	biolink:NamedThing	mitochondrial creatine kinase complex	An octomeric protein complex having creatine kinase activity.	tmpzr1t_l9r_go_relaxed.owl								hjd	2011-06-14T02:15:29Z					cellular_component											owl:Class	
GO:0070736	biolink:NamedThing	protein-glycine ligase activity, initiating	Catalysis of the posttranslational transfer of a glycine residue to the gamma-carboxyl group(s) of one or more specific glutamate residues on a target protein.	tmpzr1t_l9r_go_relaxed.owl	protein glycylase activity, initiating							mah	2009-06-19T01:56:32Z					molecular_function											owl:Class	
GO:0106001	biolink:NamedThing	intestinal hexose absorption	Uptake of hexoses, notably D-glucose, fructose, and galactose, into the blood by absorption from the small intestine.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0044692	biolink:NamedThing	exoribonuclease activator activity	Binds to and increases the activity of an exoribonuclease.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-08-15T15:13:57Z					molecular_function											owl:Class	
GO:0098645	biolink:NamedThing	collagen network	A supramolecular complex that consists of collagen triple helices associated to form a network.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0051262	biolink:NamedThing	protein tetramerization	The formation of a protein tetramer, a macromolecular structure consisting of four noncovalently associated identical or nonidentical subunits.	tmpzr1t_l9r_go_relaxed.owl	protein tetramer biosynthetic process|protein tetramer formation|protein tetramer biosynthesis|protein tetramer assembly													biological_process											owl:Class	
GO:0031863	biolink:NamedThing	prostaglandin D2 receptor binding	Binding to a prostaglandin D2 receptor.	tmpzr1t_l9r_go_relaxed.owl	prostaglandin D2 receptor ligand|prostanoid DP receptor binding													molecular_function											owl:Class	
GO:1902958	biolink:NamedThing	positive regulation of mitochondrial electron transport, NADH to ubiquinone	Any process that activates or increases the frequency, rate or extent of mitochondrial electron transport, NADH to ubiquinone.	tmpzr1t_l9r_go_relaxed.owl	upregulation of complex I (NADH to ubiquinone)|activation of oxidative phosphorylation, NADH to ubiquinone|up-regulation of complex I (NADH to ubiquinone)|up-regulation of mitochondrial electron transport, NADH to ubiquinone|positive regulation of complex I (NADH to ubiquinone)|up regulation of oxidative phosphorylation, NADH to ubiquinone|positive regulation of oxidative phosphorylation, NADH to ubiquinone|up regulation of mitochondrial electron transport, NADH to ubiquinone|upregulation of mitochondrial electron transport, NADH to ubiquinone|activation of mitochondrial electron transport, NADH to ubiquinone|up-regulation of oxidative phosphorylation, NADH to ubiquinone|activation of complex I (NADH to ubiquinone)|upregulation of oxidative phosphorylation, NADH to ubiquinone|up regulation of complex I (NADH to ubiquinone)							dph	2014-05-02T15:30:24Z					biological_process											owl:Class	
GO:0090522	biolink:NamedThing	vesicle tethering involved in exocytosis	The initial, indirect interaction between a secretory vesicle membrane and a site of exocytosis in the plasma membrane. This interaction is mediated by tethering factors (or complexes), which interact with both membranes. Interaction can occur via direct binding  to membrane phospholipids or membrane proteins, or via binding to vesicle coat proteins. This process is distinct from and prior to docking and fusion.	tmpzr1t_l9r_go_relaxed.owl	vesicle tethering to plasma membrane							tb	2013-01-08T15:07:50Z					biological_process											owl:Class	
GO:0018005	biolink:NamedThing	N-terminal peptidyl-glycine N-formylation	The formylation of the N-terminal glycine of proteins to form the derivative N-formylglycine.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0057									biological_process											owl:Class	
GO:0044108	biolink:NamedThing	cellular alcohol biosynthetic process	The chemical reactions and pathways resulting in the formation of alcohols, any of a class of compounds containing one or more hydroxyl groups attached to a saturated carbon atom, carried out at the level of an individual cell.	tmpzr1t_l9r_go_relaxed.owl								jl	2009-07-15T01:38:25Z					biological_process											owl:Class	
GO:0090540	biolink:NamedThing	bacterial cellulose biosynthetic process	The chemical reactions and pathways resulting in the formation of cellulose, a linear beta1-4 glucan of molecular mass 50-400 kDa with the pyranose units in the -4C1 conformation, as it occurs in certain types of bacteria, mainly Acetobacter, Sarcina ventriculi and Agrobacteria.	tmpzr1t_l9r_go_relaxed.owl	bacterial cellulose biosynthesis							tb	2013-02-11T16:32:44Z					biological_process											owl:Class	
GO:1903192	biolink:NamedThing	sesquarterpene metabolic process	The chemical reactions and pathways involving sesquarterpene.	tmpzr1t_l9r_go_relaxed.owl	sesquarterpene metabolism							tt	2014-07-16T17:04:47Z					biological_process											owl:Class	
GO:1990257	biolink:NamedThing	piccolo-bassoon transport vesicle	A cytoplasmic dense-core vesicle that transports a range of proteins including piccolo, bassoon, N-cadherin and syntaxin. The transported proteins may be associated with the external side of the vesicle, rather than being contained within the vesicle, therefore forming an aggregate of vesicle and proteins. Piccolo-bassoon transport vesicles (or PTVs) range in size from approximately 80 nm in diameter for dense core vesicles to 130 nm by 220 nm in area for aggregates. They are packaged via the trans-Golgi network before being transported through the axon.	tmpzr1t_l9r_go_relaxed.owl	PTV							pr	2013-12-19T14:12:09Z					cellular_component											owl:Class	
GO:0009386	biolink:NamedThing	translational attenuation	Translational attenuation is a regulatory mechanism analogous to ribosome-mediated transcriptional attenuation. The system requires the presence of a short ORF, called a leader peptide, encoded in the mRNA upstream of the ribosome-binding site and start codon of the gene whose translation is to be regulated. Certain conditions, such as presence of the antibiotic tetracycline in bacteria or amino acid starvation, may cause slowing or stalling of the ribosome translating the leader peptide. The stalled ribosome masks a region of the mRNA and affects which of two alternative mRNA folded structures will form, therefore controlling whether or not a ribosome will bind and initiate translation of the downstream gene. Translational attenuation is analogous to ribosome-mediated transcriptional attenuation, in which mRNA remodeling caused by ribosome stalling regulates transcriptional termination rather than translational initiation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0102410	biolink:NamedThing	quercetin-4',3-O-glucosyltransferase activity	Catalysis of the reaction: quercetin 4'-O-glucoside + UDP-alpha-D-glucose(2-) <=> quercetin 3,4'-O-diglucoside + UDP(3-).	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-13765									molecular_function											owl:Class	
GO:0015186	biolink:NamedThing	L-glutamine transmembrane transporter activity	Enables the transfer of L-glutamine from one side of a membrane to the other. L-glutamine is 2-amino-4-carbamoylbutanoic acid.	tmpzr1t_l9r_go_relaxed.owl	asparagine/glutamine permease activity													molecular_function											owl:Class	
GO:0052769	biolink:NamedThing	beta-6-sulfate-N-acetylglucosaminidase activity	Catalysis of the glycosidic cleavage of the terminal 2-acetamido-2-deoxy-beta-D-glucopyranoside 6-sulfate (6-SO3-GlcNAc) residue from sulfomucin, a sulfated mucin derivative.	tmpzr1t_l9r_go_relaxed.owl	sulfoglycosidase activity|sulfomucin beta-6-sulfate-N-acetylglucosaminidase activity|exosulfoglycosidase activity|beta-6-SO3-N-acetylglucosaminidase activity							ai	2011-09-30T12:55:24Z					molecular_function											owl:Class	
GO:0150074	biolink:NamedThing	positive regulation of protein-glutamine gamma-glutamyltransferase activity	Any process that activates or increases the frequency, rate or extent of protein-glutamine gamma-glutamyltransferase activity.	tmpzr1t_l9r_go_relaxed.owl								bc	2018-07-25T10:08:19Z					biological_process											owl:Class	
GO:1900550	biolink:NamedThing	N',N'',N'''-triacetylfusarinine C catabolic process	The chemical reactions and pathways resulting in the breakdown of N',N'',N'''-triacetylfusarinine C.	tmpzr1t_l9r_go_relaxed.owl	N',N'',N'''-triacetylfusarinine C catabolism|N',N'',N'''-triacetylfusarinine C breakdown|N',N'',N'''-triacetylfusarinine C degradation							di	2012-05-15T01:00:07Z					biological_process											owl:Class	
GO:1904906	biolink:NamedThing	positive regulation of endothelial cell-matrix adhesion via fibronectin	Any process that activates or increases the frequency, rate or extent of endothelial cell-matrix adhesion via fibronectin.	tmpzr1t_l9r_go_relaxed.owl	up regulation of endothelial cell-matrix adhesion via fibronectin|upregulation of endothelial cell-matrix adhesion via fibronectin|activation of endothelial cell-matrix adhesion via fibronectin|up-regulation of endothelial cell-matrix adhesion via fibronectin							bc	2016-01-19T10:23:16Z					biological_process											owl:Class	
GO:0006201	biolink:NamedThing	GMP catabolic process to IMP	The chemical reactions and pathways resulting in the breakdown of guanosine monophosphate into other compounds, including inosine monophosphate.	tmpzr1t_l9r_go_relaxed.owl	GMP breakdown to IMP|GMP degradation to IMP													biological_process											owl:Class	
GO:0015964	biolink:NamedThing	diadenosine triphosphate catabolic process	The chemical reactions and pathways resulting in the breakdown of diadenosine triphosphate, a derivative of the nucleoside adenosine with three phosphate groups attached.	tmpzr1t_l9r_go_relaxed.owl	diadenosine triphosphate catabolism|diadenosine triphosphate degradation|diadenosine triphosphate breakdown													biological_process											owl:Class	
GO:0047929	biolink:NamedThing	gluconate dehydratase activity	Catalysis of the reaction: D-gluconate = 2-dehydro-3-deoxy-D-gluconate + H(2)O.	tmpzr1t_l9r_go_relaxed.owl	D-gluconate hydro-lyase (2-dehydro-3-deoxy-D-gluconate-forming)|D-gluconate hydro-lyase activity|D-gluconate dehydratase activity				EC:4.2.1.39|KEGG_REACTION:R01538|MetaCyc:GLUCONATE-DEHYDRATASE-RXN|RHEA:21612									molecular_function											owl:Class	
GO:1990678	biolink:NamedThing	histone H4-K16 deacetylation	The modification of histone H4 by the removal of an acetyl group from lysine at position 16 of the histone.	tmpzr1t_l9r_go_relaxed.owl								al	2015-03-02T15:25:56Z					biological_process											owl:Class	
GO:0120015	biolink:NamedThing	sterol transfer activity	Removes a sterol from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle.	tmpzr1t_l9r_go_relaxed.owl	sterol carrier activity|intermembrane sterol transfer activity	https://github.com/geneontology/go-ontology/issues/12329						krc	2017-03-17T03:46:28Z					molecular_function											owl:Class	
GO:0004919	biolink:NamedThing	interleukin-9 receptor activity	Combining with interleukin-9 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	IL-9 receptor activity|IL-9R													molecular_function											owl:Class	
GO:0052752	biolink:NamedThing	reduced coenzyme F420:heterodisulfide oxidoreductase activity	Catalysis of the reaction: reduced coenzyme F420 + CoB-S-S-CoM = coenzyme F420 + CoM-SH + CoB-SH.	tmpzr1t_l9r_go_relaxed.owl	F420H2:heterodisulfide oxidoreductase activity|coenzyme F420-dependent heterodisulfide oxidoreductase activity|F420-dependent heterodisulfide oxidoreductase activity							ai	2011-09-21T04:21:16Z					molecular_function											owl:Class	
GO:0098622	biolink:NamedThing	selenodiglutathione-disulfide reductase activity	Catalysis of the reaction: H+ + selenodiglutathione + NADPH => gluthathioselenol + glutathione + NADP+.	tmpzr1t_l9r_go_relaxed.owl					RHEA:34927|Reactome:R-HSA-2408542									molecular_function											owl:Class	
GO:1905151	biolink:NamedThing	negative regulation of voltage-gated sodium channel activity	Any process that stops, prevents or reduces the frequency, rate or extent of voltage-gated sodium channel activity.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of voltage-gated sodium channel activity|inhibition of voltage-gated sodium ion channel activity|down-regulation of voltage-gated sodium ion channel activity|down regulation of voltage gated sodium channel activity|inhibition of voltage-gated sodium channel activity|down-regulation of voltage-sensitive sodium channel|down regulation of voltage-sensitive sodium channel|down-regulation of voltage gated sodium channel activity|downregulation of voltage-dependent sodium channel activity|downregulation of voltage gated sodium channel activity|down regulation of voltage-dependent sodium channel activity|negative regulation of voltage-sensitive sodium channel|negative regulation of voltage-dependent sodium channel activity|downregulation of voltage-sensitive sodium channel|downregulation of voltage-gated sodium channel activity|down regulation of voltage-gated sodium channel activity|downregulation of voltage-gated sodium ion channel activity|inhibition of voltage-dependent sodium channel activity|inhibition of voltage-sensitive sodium channel|negative regulation of voltage-gated sodium ion channel activity|down-regulation of voltage-dependent sodium channel activity|negative regulation of voltage gated sodium channel activity|down regulation of voltage-gated sodium ion channel activity|inhibition of voltage gated sodium channel activity							sl	2016-04-15T21:47:49Z					biological_process											owl:Class	
GO:0098681	biolink:NamedThing	synaptic ribbon	A non-membrane bound, electron dense structure associated that extends perpendicular to the presynaptic membrane in ribbon synapses. The ribbon's surface is studded with small particles to which synaptic vesicles tether via fine filaments. The tethered vesicles function as a pool, several fold greater than the docked pool available for fast release, which supports sustained release of vesicles.  Synaptic ribbons may be plate like or spherical.	tmpzr1t_l9r_go_relaxed.owl								dos	2017-02-05T15:59:43Z					cellular_component											owl:Class	
GO:0001665	biolink:NamedThing	alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity	Catalysis of the reaction: CMP-N-acetylneuraminate + glycano-(1->3)-(N-acetyl-alpha-D-galactosaminyl)-glycoprotein = CMP + glycano-[(2->6)-alpha-N-acetylneuraminyl]-(N-acetyl-D-galactosaminyl)-glycoprotein.	tmpzr1t_l9r_go_relaxed.owl	CMP-N-acetylneuraminate:glycano-1,3-(N-acetyl-alpha-D-galactosaminyl)-glycoprotein alpha-2,6-N-acetylneuraminyltransferase activity|GalNAc alpha-2,6-sialyltransferase I activity				MetaCyc:2.4.99.3-RXN|Reactome:R-HSA-4084980|EC:2.4.99.3|Reactome:R-HSA-9603991|RHEA:11136									molecular_function											owl:Class	
GO:0018600	biolink:NamedThing	alpha-pinene dehydrogenase activity	Catalysis of the reaction: alpha-pinene + O2 + 2 H+ + 2 e- = H2O + myrtenol.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0709|EC:1.14.-.-									molecular_function											owl:Class	
GO:0015838	biolink:NamedThing	amino-acid betaine transport	The directed movement of betaine, the N-trimethyl derivative of an amino acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	betaine transport													biological_process											owl:Class	
GO:2000391	biolink:NamedThing	positive regulation of neutrophil extravasation	Any process that activates or increases the frequency, rate or extent of neutrophil extravasation.	tmpzr1t_l9r_go_relaxed.owl								mah	2011-02-22T11:08:42Z					biological_process											owl:Class	
GO:1902678	biolink:NamedThing	right caudal basal body	Any ciliary basal body that is part of a right caudal flagellum found in Giardia species (trophozoite stage).	tmpzr1t_l9r_go_relaxed.owl	cilial basal body of right caudal cilium|ciliary basal body of right caudal flagellum|cilium basal body of right caudal cilium|right caudal flagellum ciliary basal body|microtubule basal body of right caudal flagellum|microtubule basal body of right caudal cilium|cilial basal body of right caudal flagellum|cilium basal body of right caudal flagellum|ciliary basal body of right caudal cilium					Note that we deem cilium and microtubule-based flagellum to be equivalent. Also note that, due to the asymmetric nature of the Giardia trophozoite, this term is defined spatially as the trophozoite is viewed from the dorsal side, with the two nuclei dorsal to the ventral disc, and the ventral disc toward the anterior.		pr	2014-02-05T15:02:56Z					cellular_component											owl:Class	
GO:0000737	biolink:NamedThing	DNA catabolic process, endonucleolytic	The chemical reactions and pathways resulting in the breakdown of DNA, involving the hydrolysis of internal 3',5'-phosphodiester bonds in one or two strands of deoxyribonucleotides.	tmpzr1t_l9r_go_relaxed.owl	endonucleolytic DNA catabolism|endonucleolytic degradation of DNA|DNA degradation, endonucleolytic|DNA breakdown, endonucleolytic													biological_process											owl:Class	
GO:0072197	biolink:NamedThing	ureter morphogenesis	The process in which the anatomical structures of the ureter are generated and organized. The ureter is a muscular tube that transports urine from the kidney to the urinary bladder.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-03-01T02:24:55Z					biological_process											owl:Class	
GO:0071813	biolink:NamedThing	lipoprotein particle binding	Binding to a lipoprotein particle. A lipoprotein particle, also known as a lipoprotein, is a clathrate complex consisting of a lipid enwrapped in a protein host without covalent binding in such a way that the complex has a hydrophilic outer surface consisting of all the protein and the polar ends of any phospholipids.	tmpzr1t_l9r_go_relaxed.owl	plasma lipoprotein particle binding|plasma lipoprotein binding|lipoprotein binding							mah	2010-09-06T03:16:01Z					molecular_function											owl:Class	
GO:0071814	biolink:NamedThing	protein-lipid complex binding	Binding to a protein-lipid complex, any macromolecular complex that contains both protein and lipid molecules.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-09-06T04:26:27Z					molecular_function											owl:Class	
GO:0140626	biolink:NamedThing	opioid growth factor receptor signaling pathway	The series of molecular signals generated as a consequence of an opioid growth factor receptor binding to its physiological ligand, opioid growth factor (OGF, met-enkephalin). The OGF-OGFr complex leads to the increase in the synthesis of the selective cyclin-dependent kinase (CDK) inhibitor proteins, p12 (POLD4) and p16 (CDKN2A).	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/21110			Wikipedia:OGFr|Wikipedia:Opioid_receptor	Note that this term represents the activation of the zeta-opioid receptor. Do not confuse with GO:0038003 ; G protein-coupled opioid receptor signaling pathway, activated by the delta, kappa, mu, and nociceptin opioid receptors.		pg	2021-03-18T08:30:43Z					biological_process											owl:Class	
GO:0034615	biolink:NamedThing	GCH1 complex	A protein complex that possesses GTP cyclohydrolase I activity. In E. coli and human, the complex is a homodecamer, and monomers are catalytically inactive.	tmpzr1t_l9r_go_relaxed.owl	GTP cyclohydrolase I complex													cellular_component											owl:Class	
GO:2000455	biolink:NamedThing	regulation of T-helper 17 cell extravasation	Any process that modulates the frequency, rate or extent of T-helper 17 cell extravasation.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-03-04T10:49:51Z					biological_process											owl:Class	
GO:0034643	biolink:NamedThing	establishment of mitochondrion localization, microtubule-mediated	The directed movement of the mitochondrion to a specific location, by a process involving microtubules.	tmpzr1t_l9r_go_relaxed.owl	microtubule-mediated mitochondrion localization|establishment of mitochondrion localisation, microtubule-mediated|mitochondrial localization, microtubule-mediated													biological_process											owl:Class	
GO:0014714	biolink:NamedThing	myoblast fate commitment in head	The process, taking place in the head, whereby the developmental fate of a cell becomes restricted such that it will develop into a myoblast. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0019342	biolink:NamedThing	trypanothione biosynthetic process	The chemical reactions and pathways resulting in the formation of trypanothione (N1,N6,-bis(glutathionyl)spermidine) in two steps from glutathione and spermidine via an N1- or N8-glutathionylspermidine intermediate. Trypanothione appears to be an essential redox intermediate in intracellular thiol redox regulation. It also plays a role in protecting against oxidative stress.	tmpzr1t_l9r_go_relaxed.owl	trypanothione biosynthesis|trypanothione anabolism|trypanothione synthesis|trypanothione formation				MetaCyc:TRYPANOSYN-PWY									biological_process											owl:Class	
GO:1900184	biolink:NamedThing	negative regulation of xanthone-containing compound biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of xanthone-containing compound biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	inhibition of xanthone biosynthetic process|down regulation of xanthone-containing compound biosynthetic process|down-regulation of xanthone-containing compound biosynthesis|inhibition of xanthone-containing compound biosynthesis|down regulation of xanthone-containing compound formation|down regulation of xanthone-containing compound synthesis|down regulation of xanthone biosynthetic process|inhibition of xanthone biosynthesis|downregulation of xanthone biosynthetic process|downregulation of xanthone-containing compound formation|downregulation of xanthone-containing compound synthesis|negative regulation of xanthone-containing compound formation|inhibition of xanthone-containing compound formation|down-regulation of xanthone biosynthetic process|downregulation of xanthone-containing compound biosynthetic process|downregulation of xanthone biosynthesis|down-regulation of xanthone biosynthesis|negative regulation of xanthone-containing compound synthesis|down regulation of xanthone-containing compound biosynthesis|downregulation of xanthone-containing compound biosynthesis|down regulation of xanthone biosynthesis|inhibition of xanthone-containing compound synthesis|negative regulation of xanthone-containing compound anabolism|negative regulation of xanthone-containing compound biosynthesis|negative regulation of xanthone biosynthesis|negative regulation of xanthone biosynthetic process|inhibition of xanthone-containing compound anabolism|down-regulation of xanthone-containing compound synthesis|down regulation of xanthone-containing compound anabolism|negative regulation of xanthones anabolism|down-regulation of xanthone-containing compound biosynthetic process|down-regulation of xanthone-containing compound anabolism|downregulation of xanthone-containing compound anabolism|down-regulation of xanthone-containing compound formation|inhibition of xanthone-containing compound biosynthetic process							di	2012-03-16T03:30:24Z					biological_process											owl:Class	
GO:0071653	biolink:NamedThing	negative regulation of chemokine (C-C motif) ligand 1 production	Any process that stops, prevents, or reduces the frequency, rate, or extent of production of chemokine (C-C motif) ligand 1.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of CCL1 production|negative regulation of T cell activation 3 production|negative regulation of TCA-3 production							mah	2010-02-12T10:41:14Z					biological_process											owl:Class	
GO:0050117	biolink:NamedThing	N-acetyl-beta-alanine deacetylase activity	Catalysis of the reaction: N-acetyl-beta-alanine + H(2)O = beta-alanine + acetate.	tmpzr1t_l9r_go_relaxed.owl	N-acetyl-beta-alanine amidohydrolase activity				RHEA:23212|EC:3.5.1.21|KEGG_REACTION:R00909|MetaCyc:N-ACETYL-BETA-ALANINE-DEACETYLASE-RXN									molecular_function											owl:Class	
GO:0048355	biolink:NamedThing	root cap mucilage biosynthetic process	The chemical reactions and pathways resulting in the formation of mucilage that occur in the root cap; mucilage is normally synthesized during root growth.	tmpzr1t_l9r_go_relaxed.owl	root cap mucilage anabolism|root cap mucilage formation|root cap mucilage biosynthesis|root cap mucilage synthesis													biological_process											owl:Class	
GO:0010192	biolink:NamedThing	mucilage biosynthetic process	The chemical reactions and pathways resulting in the formation of mucilage, a gelatinous substance secreted by plants.	tmpzr1t_l9r_go_relaxed.owl	mucilage anabolism|mucilage synthesis|mucilage biosynthesis|mucilage formation													biological_process											owl:Class	
GO:0016080	biolink:NamedThing	synaptic vesicle targeting	The process in which synaptic vesicles are directed to specific destination membranes, mediated by molecules at the vesicle membrane and target membrane surfaces.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0061127	biolink:NamedThing	negative regulation of positive chemotaxis to cAMP by DIF-1	Any process that decreases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of DIF-1. DIF-1 is a chlorinated alkylphenone.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-05-17T08:45:03Z					biological_process											owl:Class	
GO:0140296	biolink:NamedThing	general transcription initiation factor binding	Binding to a general transcription initiation factor, a protein that contributes to transcription start site selection and transcription initiation.	tmpzr1t_l9r_go_relaxed.owl								pg	2018-11-28T12:48:06Z					molecular_function											owl:Class	
GO:0031262	biolink:NamedThing	Ndc80 complex	An outer kinetochore protein complex that is part of the KMN kinetochore network (also known as the NMS complex) providing the platform with which the plus ends of spindle microtubules directly interact to form stable kinetochore-microtubule attachments. A common subunit nomenclature is used from yeast to human: Ndc80, Nuf2, Spc24, and Spc25.	tmpzr1t_l9r_go_relaxed.owl	Nuf2-Ndc80 complex													cellular_component											owl:Class	
GO:1902716	biolink:NamedThing	cell cortex of growing cell tip	Any cell cortex that is part of a growing cell tip.	tmpzr1t_l9r_go_relaxed.owl	cell cortex of growing cell end							mah	2014-02-24T15:46:57Z					cellular_component											owl:Class	
GO:1904156	biolink:NamedThing	DN3 thymocyte differentiation	The process in which a relatively unspecialized cell acquires the specialized features of a DN3 thymocyte. A DN3 thymocyte is a CD4-,CD8- thymocyte that is also CD44+,CD25+.	tmpzr1t_l9r_go_relaxed.owl								dph	2015-04-15T12:53:00Z					biological_process											owl:Class	
GO:0050468	biolink:NamedThing	reticuline oxidase activity	Catalysis of the reaction: (S)-reticuline + O(2) = (S)-scoulerine + H(2)O(2) + H(+).	tmpzr1t_l9r_go_relaxed.owl	BBE|(S)-reticuline:oxygen oxidoreductase (methylene-bridge-forming)|berberine bridge enzyme activity|tetrahydroprotoberberine synthase activity|berberine-bridge-forming enzyme activity				MetaCyc:RETICULINE-OXIDASE-RXN|RHEA:19885|KEGG_REACTION:R03831|EC:1.21.3.3									molecular_function											owl:Class	
GO:0070224	biolink:NamedThing	sulfide:quinone oxidoreductase activity	Catalysis of the reaction: hydrogen sulfide + a quinone = S0 + a hydroquinone.	tmpzr1t_l9r_go_relaxed.owl	sulphide:quinone oxidoreductase activity|sulfide-quinone reductase activity				Reactome:R-HSA-1614665|MetaCyc:R17-RXN|RHEA:30239									molecular_function											owl:Class	
GO:1903877	biolink:NamedThing	21-deoxycortisol binding	Binding to 21-deoxycortisol.	tmpzr1t_l9r_go_relaxed.owl								mr	2015-02-06T16:02:54Z					molecular_function											owl:Class	
GO:1990384	biolink:NamedThing	hyaloid vascular plexus regression	The developmental process in which the hyaloid vascular plexus is destroyed as a part of its normal progression.	tmpzr1t_l9r_go_relaxed.owl								hjd	2014-05-28T18:43:21Z					biological_process											owl:Class	
GO:0052155	biolink:NamedThing	modulation by symbiont of host cell-mediated immune response	Any process in which an organism modulates the frequency, rate or extent of any form of cell-based immune response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	modulation by organism of host cell-based immune response|modulation by organism of cell-mediated immune response of other organism involved in symbiotic interaction											GO:0052294		biological_process											owl:Class	
GO:0022004	biolink:NamedThing	midbrain-hindbrain boundary maturation during brain development	A developmental process occurring after the brain has been specified along the neural axis that is required for the midbrain-hindbrain boundary to attain its fully functional state. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0052386	biolink:NamedThing	cell wall thickening	A type of cell wall modification in which the cell wall is reinforced and made thicker.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0103041	biolink:NamedThing	thiosulfate-thioredoxin sulfurtransferase activity	Catalysis of the reaction: hydroxidodioxidosulfidosulfate + a reduced thioredoxin = sulfite + hydrogen sulfide + H+ + an oxidized thioredoxin.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN0-6385									molecular_function											owl:Class	
GO:0044098	biolink:NamedThing	DNA secretion by the type IV secretion system	The controlled release of DNA by a cell, via the type IV secretion system.	tmpzr1t_l9r_go_relaxed.owl	DNA secretion via the type IV secretion system							jl	2009-06-09T02:26:57Z					biological_process											owl:Class	
GO:0036243	biolink:NamedThing	succinate-semialdehyde dehydrogenase (NADP+) activity	Catalysis of the reaction: succinate semialdehyde + NADP+ + H2O = succinate + NADPH + 2 H+.	tmpzr1t_l9r_go_relaxed.owl	NADP-dependent succinate-semialdehyde dehydrogenase activity|succinate semialdehyde:NADP+ oxidoreductase activity|succinic semialdehyde dehydrogenase (NADP+) activity|succinyl semialdehyde dehydrogenase (NADP+) activity				RHEA:13213|EC:1.2.1.79	This function is similar to EC:1.2.1.24 [succinate-semialdehyde dehydrogenase (NAD+)], and EC:1.2.1.16 [succinate-semialdehyde dehydrogenase (NAD(P)+)], but is specific for NADP+.		bf	2012-05-23T02:47:52Z					molecular_function											owl:Class	
GO:0016941	biolink:NamedThing	natriuretic peptide receptor activity	Combining with a natriuretic peptide and transmitting the signal to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0018297	biolink:NamedThing	protein-FAD linkage via 1'-(8alpha-FAD)-L-histidine	The formation of a protein-FAD linkage via 1'-(8-alpha-FAD)-L-histidine.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0221									biological_process											owl:Class	
GO:0099157	biolink:NamedThing	trans-synaptic signalling via exosome	Transynaptic signaling in which the ligand is carried across the synapse by an exosome.	tmpzr1t_l9r_go_relaxed.owl	exosome mediated transynaptic signalling							dos	2017-07-05T16:49:44Z					biological_process											owl:Class	
GO:0019703	biolink:NamedThing	coenzyme A-peptidyl-cysteine covalent linking	The covalent linkage of coenzyme A and peptidyl-cysteine to form L-cysteine coenzyme A disulfide.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0306									biological_process											owl:Class	
GO:0043485	biolink:NamedThing	endosome to pigment granule transport	The directed movement of substances from endosomes to pigment granules.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0055112	biolink:NamedThing	delamination involved in gastrulation with mouth forming second	The splitting or migration of one epithelial sheet into two involved in the process of deuterostomic gastrulation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0046183	biolink:NamedThing	L-idonate catabolic process	The chemical reactions and pathways resulting in the breakdown of L-idonate, the anion of idonic acid, an aldonic acid derived from L-idose, an aldohexose which is epimeric with D-glucose.	tmpzr1t_l9r_go_relaxed.owl	L-idonate degradation|L-idonate breakdown|L-idonate catabolism													biological_process											owl:Class	
GO:0003874	biolink:NamedThing	6-pyruvoyltetrahydropterin synthase activity	Catalysis of the reaction: 7,8-dihydroneopterin 3'-triphosphate = 6-pyruvoyl-5,6,7,8-tetrahydropterin + H(+) + triphosphate.	tmpzr1t_l9r_go_relaxed.owl	2-amino-4-oxo-6-[(1S,2R)-1,2-dihydroxy-3-triphosphooxypropyl]-7,8-dihydroxypteridine triphosphate lyase activity|PTPS activity|6-pyruvoyl tetrahydrobiopterin synthase activity|2-amino-4-oxo-6-[(1S,2R)-1,2-dihydroxy-3-triphosphooxypropyl]-7,8-dihydroxypteridine triphosphate-lyase (6-pyruvoyl-5,6,7,8-tetrahydropterin-forming)				KEGG_REACTION:R04286|RHEA:22048|MetaCyc:4.2.3.12-RXN|Reactome:R-HSA-1474184|EC:4.2.3.12									molecular_function											owl:Class	
GO:0009716	biolink:NamedThing	flavonoid phytoalexin biosynthetic process	The chemical reactions and pathways resulting in the formation of flavonoid phytoalexins, a group of water-soluble phenolic derivatives containing a flavan skeleton, which possess antibiotic activity and are produced by plant tissues in response to infection.	tmpzr1t_l9r_go_relaxed.owl	flavonoid phytoalexin synthesis|flavonoid phytoalexin anabolism|flavonoid phytoalexin biosynthesis|flavonoid phytoalexin formation													biological_process											owl:Class	
GO:0040026	biolink:NamedThing	positive regulation of vulval development	Any process that activates or increases the frequency, rate or extent of development of the vulva. Vulval development is the process whose specific outcome is the progression of the egg-laying organ of female and hermaphrodite nematodes over time, from its formation to the mature structure. In nematodes, the vulva is formed from ventral epidermal cells during larval stages to give rise to a fully formed vulva in the adult.	tmpzr1t_l9r_go_relaxed.owl	up regulation of vulval development|activation of vulval development|stimulation of vulval development|up-regulation of vulval development|upregulation of vulval development													biological_process											owl:Class	
GO:0040028	biolink:NamedThing	regulation of vulval development	Any process that modulates the frequency, rate or extent of development of the vulva. Vulval development is the process whose specific outcome is the progression of the egg-laying organ of female and hermaphrodite nematodes over time, from its formation to the mature structure. In nematodes, the vulva is formed from ventral epidermal cells during larval stages to give rise to a fully formed vulva in the adult.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1904868	biolink:NamedThing	telomerase catalytic core complex assembly	The aggregation, arrangement and bonding together of a set of components to form a telomerase catalytic core complex.	tmpzr1t_l9r_go_relaxed.owl	telomerase catalytic core complex formation|TERT-TERC complex formation|TERT-TERC complex assembly							rph	2015-12-18T10:02:45Z					biological_process											owl:Class	
GO:1905323	biolink:NamedThing	telomerase holoenzyme complex assembly	The aggregation, arrangement and bonding together of a set of components to form a telomerase holoenzyme complex.	tmpzr1t_l9r_go_relaxed.owl	telomerase holoenzyme complex formation							mah	2016-07-18T10:38:14Z					biological_process											owl:Class	
GO:0044129	biolink:NamedThing	positive regulation of development of symbiont in host	Any process in which the symbiont activates or maintains its progression from an initial condition to a later condition, within the cells or tissues of the host organism. The host is defined as the larger of the organisms involved in the symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl						This term partially replaces the obsolete term 'positive regulation of growth or development of symbiont in host ; GO:0033666'. See also 'positive regulation of growth of symbiont in host ; GO:0044128'.		jl	2009-08-04T02:25:41Z					biological_process											owl:Class	
GO:0004026	biolink:NamedThing	alcohol O-acetyltransferase activity	Catalysis of the reaction: acetyl-CoA + an alcohol = CoA + an acetyl ester.	tmpzr1t_l9r_go_relaxed.owl	alcohol acetyltransferase activity|AATASE activity|acetyl-CoA:alcohol O-acetyltransferase activity				EC:2.3.1.84|RHEA:17229|MetaCyc:ALCOHOL-O-ACETYLTRANSFERASE-RXN									molecular_function											owl:Class	
GO:0016920	biolink:NamedThing	pyroglutamyl-peptidase activity	Catalysis of the release of the N-terminal pyroglutamyl group from a peptide or protein.	tmpzr1t_l9r_go_relaxed.owl					EC:3.4.19.-									molecular_function											owl:Class	
GO:1905601	biolink:NamedThing	negative regulation of receptor-mediated endocytosis involved in cholesterol transport	Any process that stops, prevents or reduces the frequency, rate or extent of receptor-mediated endocytosis involved in cholesterol transport.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of receptor-mediated endocytosis involved in intracellular cholesterol transport|down-regulation of receptor-mediated endocytosis of low-density lipoprotein involved in cholesterol transport|negative regulation of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport|down regulation of receptor-mediated endocytosis involved in intracellular cholesterol transport|inhibition of receptor-mediated endocytosis of LDL|downregulation of receptor-mediated endocytosis involved in intracellular cholesterol transport|inhibition of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport|inhibition of receptor-mediated endocytosis involved in cholesterol transport|down-regulation of receptor-mediated endocytosis of LDL|down-regulation of receptor-mediated endocytosis involved in intracellular cholesterol transport|down regulation of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport|negative regulation of receptor-mediated endocytosis of low-density lipoprotein involved in cholesterol transport|downregulation of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport|negative regulation of receptor-mediated endocytosis of LDL|down-regulation of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport|downregulation of receptor-mediated endocytosis involved in cholesterol transport|down regulation of receptor-mediated endocytosis of low-density lipoprotein involved in cholesterol transport|downregulation of receptor-mediated endocytosis of LDL|down regulation of receptor-mediated endocytosis involved in cholesterol transport|downregulation of receptor-mediated endocytosis of low-density lipoprotein involved in cholesterol transport|down-regulation of receptor-mediated endocytosis involved in cholesterol transport|inhibition of receptor-mediated endocytosis of low-density lipoprotein involved in cholesterol transport|down regulation of receptor-mediated endocytosis of LDL|inhibition of receptor-mediated endocytosis involved in intracellular cholesterol transport							pr	2016-10-26T13:01:52Z					biological_process											owl:Class	
GO:0061207	biolink:NamedThing	mesonephric juxtaglomerulus cell differentiation	The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the juxtaglomerulus cells of the mesonephros as it progresses from its formation to the mature state.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-08-19T12:54:08Z					biological_process											owl:Class	
GO:0102796	biolink:NamedThing	protocatechualdehyde:oxygen oxidoreductase activity	Catalysis of the reaction: 3,4-dihydroxybenzaldehyde + O2 + H2O <=> H+ + 3,4-dihydroxybenzoate + hydrogen peroxide.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-8091|EC:1.2.3.9									molecular_function											owl:Class	
GO:0075503	biolink:NamedThing	fusion of virus membrane with host macropinosome membrane	Fusion of a viral membrane with a host macropinosome membrane, that occurs after internalization of the virus through the endosomal pathway, and results in release of the viral contents into the host cell cytoplasm.	tmpzr1t_l9r_go_relaxed.owl	viral entry into host cell via macropinocytosis followed by membrane fusion with the endosome membrane|viral entry into host cell via macropinocytosis followed by membrane fusion with the host macropinosome membrane							jl	2010-06-02T02:45:47Z					biological_process											owl:Class	
GO:0070356	biolink:NamedThing	synaptotagmin-synaptobrevin 2-SNAP-25-syntaxin-1a-syntaxin-1b-Rab3a complex	A SNARE complex that contains synaptotagmin, synaptobrevin 2 (VAMP2), SNAP-25, syntaxin 1a, syntaxin1b, and Rab3a (or orthologs thereof).	tmpzr1t_l9r_go_relaxed.owl	SNARE complex (STX1a, STX1b, SNAP25, RAB3a, SYT1, VAMP2)|STX1a-STX1b-SNAP25-RAB3a-SYT1-VAMP2 complex													cellular_component											owl:Class	
GO:1990324	biolink:NamedThing	collagen type XXVI trimer	A collagen homotrimer of alpha1(XXVI) chains.	tmpzr1t_l9r_go_relaxed.owl								bhm	2014-03-16T23:02:35Z					cellular_component											owl:Class	
GO:0080017	biolink:NamedThing	alpha-humulene synthase activity	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = alpha-humulene + diphosphate.	tmpzr1t_l9r_go_relaxed.owl					RHEA:31895|EC:4.2.3.104|MetaCyc:RXN-8415									molecular_function											owl:Class	
GO:0090692	biolink:NamedThing	mitochondrial membrane scission site	The site on the mitochondrial membrane where the separation of a single continuous mitochondrial membrane into two membranes occurs as a final step in mitochondrial fission.	tmpzr1t_l9r_go_relaxed.owl								tb	2016-08-24T10:46:09Z					cellular_component											owl:Class	
GO:0034391	biolink:NamedThing	regulation of smooth muscle cell apoptotic process	Any process that modulates the frequency, rate, or extent of smooth muscle cell apoptotic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of SMC apoptosis|regulation of smooth muscle cell apoptosis													biological_process											owl:Class	
GO:0044188	biolink:NamedThing	host cell lysosomal membrane	The lipid bilayer surrounding the host cell lysosome and separating its contents from the host cell cytoplasm.	tmpzr1t_l9r_go_relaxed.owl								jl	2009-10-15T03:27:54Z					cellular_component											owl:Class	
GO:0061569	biolink:NamedThing	UDP phosphorylation	The process of introducing a phosphate group into UDP, uridine diphosphate, to produce UTP.	tmpzr1t_l9r_go_relaxed.owl								dph	2013-08-01T12:59:32Z					biological_process											owl:Class	
GO:0021501	biolink:NamedThing	prechordal plate formation	The formation of the prechordal plate. The prechordal plate is a thickening of the endoderm at the cranial end of the primitive streak formed by the involution of Spemann's organizer cells. The prechordal plate and the notochord induce the formation of the neural plate from the overlying ectodermal cells.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0050223	biolink:NamedThing	protocatechuate decarboxylase activity	Catalysis of the reaction: 3,4-dihydroxybenzoate + H(+) = catechol + CO(2).	tmpzr1t_l9r_go_relaxed.owl	3,4-dihydrobenzoate decarboxylase activity|3,4-dihydroxybenzoate decarboxylase activity|3,4-dihydroxybenzoate carboxy-lyase (catechol-forming)|protocatechuate carboxy-lyase activity				KEGG_REACTION:R00822|EC:4.1.1.63|RHEA:22416|MetaCyc:PROTOCATECHUATE-DECARBOXYLASE-RXN									molecular_function											owl:Class	
GO:0018954	biolink:NamedThing	pentaerythritol tetranitrate metabolic process	The chemical reactions and pathways involving pentaerythritol tetranitrate, C(CH2-O-NO2)4, a substance produced for use as an explosive and a vasodilator.	tmpzr1t_l9r_go_relaxed.owl	pentaerythritol tetranitrate metabolism				UM-BBD_pathwayID:petn									biological_process											owl:Class	
GO:0033927	biolink:NamedThing	glucan 1,4-alpha-maltohexaosidase activity	Catalysis of the hydrolysis of (1->4)-alpha-D-glucosidic linkages in amylaceous polysaccharides, to remove successive maltohexaose residues from the non-reducing chain ends.	tmpzr1t_l9r_go_relaxed.owl	G6-amylase activity|1,4-alpha-D-glucan maltohexaohydrolase activity|maltohexaose-producing amylase activity|exo-maltohexaohydrolase activity				MetaCyc:3.2.1.98-RXN|EC:3.2.1.98									molecular_function											owl:Class	
GO:0015759	biolink:NamedThing	beta-glucoside transport	The directed movement of beta-glucosides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Beta-glucosides are glycosides in which the sugar group is a glucose residue, and the anomeric carbon of the bond is in a beta configuration.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0099148	biolink:NamedThing	regulation of synaptic vesicle docking	Any process that modulates the frequency, rate or extent of synaptic vesicle docking.	tmpzr1t_l9r_go_relaxed.owl								dos	2017-07-05T13:10:10Z					biological_process											owl:Class	
GO:0048724	biolink:NamedThing	epistomal sclerite development	The process whose specific outcome is the progression of the epistomal sclerite over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0034006	biolink:NamedThing	amorpha-4,11-diene synthase activity	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = amorpha-4,11-diene + diphosphate.	tmpzr1t_l9r_go_relaxed.owl	2-trans,6-trans-farnesyl-diphosphate diphosphate-lyase (amorpha-4,11-diene-forming) activity|amorphadiene synthase activity				MetaCyc:4.2.3.24-RXN|EC:4.2.3.24|RHEA:18325|MetaCyc:RXN-8046|KEGG_REACTION:R07630									molecular_function											owl:Class	
GO:0071831	biolink:NamedThing	intermediate-density lipoprotein particle clearance	The process in which a intermediate-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.	tmpzr1t_l9r_go_relaxed.owl	IDL clearance							mah	2010-09-08T11:26:12Z					biological_process											owl:Class	
GO:0009496	biolink:NamedThing	plastoquinol--plastocyanin reductase activity	Catalysis of the reaction: 2 H(+)[side 1] + 2 oxidized plastocyanin + plastoquinol-1 = 2 H(+)[side 2] + 2 reduced plastocyanin + plastoquinone. This reaction involves the concomitant transfer of 2 H+ ions across a membrane.	tmpzr1t_l9r_go_relaxed.owl	plastoquinol:oxidized-plastocyanin oxidoreductase activity|cytochrome b6f|plastoquinol-plastocyanin reductase activity|plastoquinol/plastocyanin oxidoreductase activity|cytochrome b6f complex activity				MetaCyc:PLASTOQUINOL--PLASTOCYANIN-REDUCTASE-RXN|RHEA:22148|KEGG_REACTION:R03817|EC:7.1.1.6									molecular_function											owl:Class	
GO:0031436	biolink:NamedThing	BRCA1-BARD1 complex	A heterodimeric complex comprising BRCA1 and BARD1, which possesses ubiquitin ligase activity and is involved in genome maintenance, possibly by functioning in surveillance for DNA damage.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0102798	biolink:NamedThing	heptaldehyde:oxygen oxidoreductase activity	Catalysis of the reaction: heptanal + O2 + H2O = H+ + heptanoate + hydrogen peroxide.	tmpzr1t_l9r_go_relaxed.owl					EC:1.2.3.1|MetaCyc:RXN-8094									molecular_function											owl:Class	
GO:0032798	biolink:NamedThing	Swi5-Sfr1 complex	A conserved DNA recombinase mediator complex that contains two Swi5 monomers and one Sfr1 monomer in Schizosaccharomyces, or orthologs thereof (e.g. Sae3p and Mei5p in Saccharomyces).	tmpzr1t_l9r_go_relaxed.owl	Sae3-Mei5 complex|Swi5 complex					Note that this term refers to Schizosaccharomyces pombe Swi5, which should not be confused with the unrelated Saccharomyces Swi5p.								cellular_component											owl:Class	
GO:0140489	biolink:NamedThing	molecular template activity	The action of a molecule that provides a shape or a sequence mimicking or complementary to the final product, providing template for copying the original molecule's shape or sequence.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/19709						pg	2020-07-01T08:42:18Z					molecular_function											owl:Class	
GO:0140457	biolink:NamedThing	protein demethylase activity	Catalysis of the removal of a methyl group from a protein.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/19325						pg	2020-04-23T07:39:14Z					molecular_function											owl:Class	
GO:0033914	biolink:NamedThing	xylan 1,3-beta-xylosidase activity	Catalysis of the hydrolysis of successive xylose residues from the non-reducing termini of (1->3)-beta-D-xylans.	tmpzr1t_l9r_go_relaxed.owl	1,3-beta-D-xylan xylohydrolase activity|1,3-beta-D-xylosidase, exo-1,3-beta-xylosidase activity|beta-1,3'-xylanase activity|exo-beta-1,3'-xylanase activity|exo-1,3-beta-xylosidase activity				MetaCyc:3.2.1.72-RXN|EC:3.2.1.72									molecular_function											owl:Class	
GO:1903700	biolink:NamedThing	caecum development	The process whose specific outcome is the progression of a caecum over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl	blindgut development|intestinum caecum development|blind intestine development|cecum development|ceca development|intestinum crassum caecum development|caeca development|intestinum crassum cecum development							cls	2014-12-03T12:05:00Z					biological_process											owl:Class	
GO:0018219	biolink:NamedThing	peptidyl-cysteine S-acetylation	The acetylation of peptidyl-cysteine to form peptidyl-S-acetyl-L-cysteine.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0056									biological_process											owl:Class	
GO:0019103	biolink:NamedThing	pyrimidine nucleotide binding	Binding to a pyrimidine nucleotide, a pyrimidine nucleoside esterified with (ortho)phosphate.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1902184	biolink:NamedThing	negative regulation of shoot apical meristem development	Any process that stops, prevents or reduces the frequency, rate or extent of shoot apical meristem development.	tmpzr1t_l9r_go_relaxed.owl	downregulation of promeristem development|down-regulation of SAM development|down-regulation of primary shoot meristem development|downregulation of shoot apical meristem development|inhibition of promeristem development|downregulation of SAM development|down-regulation of promeristem development|inhibition of SAM development|down regulation of shoot apical meristem development|downregulation of primary shoot meristem development|down regulation of SAM development|negative regulation of promeristem development|down regulation of primary shoot meristem development|inhibition of shoot apical meristem development|down regulation of promeristem development|negative regulation of SAM development|down-regulation of shoot apical meristem development|negative regulation of primary shoot meristem development|inhibition of primary shoot meristem development							tb	2013-05-31T16:34:00Z					biological_process											owl:Class	
GO:2001293	biolink:NamedThing	malonyl-CoA metabolic process	The chemical reactions and pathways involving malonyl-CoA, the S-malonyl derivative of coenzyme A.	tmpzr1t_l9r_go_relaxed.owl	malonyl-CoA metabolism							pr	2012-02-14T02:23:11Z					biological_process											owl:Class	
GO:0033405	biolink:NamedThing	UCU codon-amino acid adaptor activity	A triplet codon-amino acid adaptor activity that recognizes a UCU codon.	tmpzr1t_l9r_go_relaxed.owl	serine tRNA|TCT codon-amino acid adaptor activity					Note that in the standard genetic code, TCT codes for serine.								molecular_function											owl:Class	
GO:0047797	biolink:NamedThing	cyclohexanone dehydrogenase activity	Catalysis of the reaction: A + cyclohexanone = AH(2) + cyclohex-2-enone.	tmpzr1t_l9r_go_relaxed.owl	cyclohexanone:(acceptor) 2-oxidoreductase activity|cyclohexanone:acceptor 2-oxidoreductase activity				RHEA:21780|EC:1.3.99.14|KEGG_REACTION:R02234|MetaCyc:CYCLOHEXANONE-DEHYDROGENASE-RXN									molecular_function											owl:Class	
GO:0030377	biolink:NamedThing	urokinase plasminogen activator receptor activity	Combining with the urokinase plasminogen activator to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	uPAR|U-plasminogen activator receptor activity|urokinase plasminogen activator receptor				Wikipedia:Urokinase_receptor									molecular_function											owl:Class	
GO:0034987	biolink:NamedThing	immunoglobulin receptor binding	Binding to one or more specific sites on an immunoglobulin receptor molecule.	tmpzr1t_l9r_go_relaxed.owl	Fc receptor binding													molecular_function											owl:Class	
GO:0071685	biolink:NamedThing	NADH dehydrogenase complex (plastoquinone)	An NADH dehydrogenase complex that catalyzes the transfer of electrons to plastoquinone. The complex is involved in the non-photochemical reduction of plastoquinones and the cyclic electron transport around photosystem I, and is found in plastid thylakoids.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-02-19T05:20:45Z					cellular_component											owl:Class	
GO:0070553	biolink:NamedThing	nicotinic acid receptor activity	Combining with nicotinic acid to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	niacin receptor activity													molecular_function											owl:Class	
GO:0062240	biolink:NamedThing	euchromatin-nuclear membrane anchor activity	Binding to euchromatin and the nuclear inner membrane, in order to establish and maintain the euchromatin location and organization.	tmpzr1t_l9r_go_relaxed.owl	euchromatin-nuclear membrane tether activity|nuclear membrane-euchromatin tether activity|nuclear membrane-euchromatin anchor activity							dph	2020-04-20T18:22:35Z					molecular_function											owl:Class	
GO:0090694	biolink:NamedThing	Scc2-Scc4 cohesin loading complex	A eukaryotically conserved heterodimeric protein complex (comprising adherin and the chromatid cohesion factor MAU2/Scc4/Ssl3) required for the loading of a cohesin, complex onto DNA.	tmpzr1t_l9r_go_relaxed.owl	Mis4-Ssl3 cohesin loading complex							tb	2016-08-24T17:09:11Z					cellular_component											owl:Class	
GO:0019285	biolink:NamedThing	glycine betaine biosynthetic process from choline	The chemical reactions and pathways resulting in the formation of betaine (N-trimethylglycine) from the oxidation of choline.	tmpzr1t_l9r_go_relaxed.owl	glycine betaine formation from choline|N-trimethylglycine biosynthesis from choline|glycine betaine anabolism from choline|choline oxidation|glycine betaine synthesis from choline|N-trimethylglycine biosynthetic process from choline				MetaCyc:P542-PWY|MetaCyc:BETSYN-PWY|MetaCyc:CHOLINE-BETAINE-ANA-PWY									biological_process											owl:Class	
GO:0106236	biolink:NamedThing	rhamnolipid biosynthesis	The chemical reactions and pathways resulting in the formation/production of a glycolipid surfactant that acts as a bacterial biofilm dispersal.	tmpzr1t_l9r_go_relaxed.owl	rhamnolipid production							hjd	2019-12-09T18:37:49Z					biological_process											owl:Class	
GO:0002626	biolink:NamedThing	negative regulation of T cell antigen processing and presentation	Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell antigen processing and presentation.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of T-cell antigen processing and presentation|down regulation of T cell antigen processing and presentation|negative regulation of T lymphocyte antigen processing and presentation|down-regulation of T cell antigen processing and presentation|inhibition of T cell antigen processing and presentation|negative regulation of T-lymphocyte antigen processing and presentation|downregulation of T cell antigen processing and presentation													biological_process											owl:Class	
GO:0018637	biolink:NamedThing	1-hydroxy-2-naphthoate hydroxylase activity	Catalysis of the reaction: 1-hydroxy-2-naphthoate + O2 + NADPH + 2 H+ = NADP+ + H2O + CO2 + 1,2-dihydroxynaphthalene.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0491|EC:1.14.13.-									molecular_function											owl:Class	
GO:0060217	biolink:NamedThing	hemangioblast cell differentiation	The process in which a relatively unspecialized cell acquires the characteristics of a mature hemangioblast. Hemangioblasts are the proposed common precursor of blood and endothelial lineages.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0052879	biolink:NamedThing	9,12-octadecadienoate 8-hydroperoxide 8S-isomerase activity	Catalysis of the reaction: (8R,9Z,12Z)-8-hydroperoxyoctadeca-9,12-dienoate = (7S,8S,9Z,12Z)-7,8-dihydroxyoctadeca-9,12-dienoate.	tmpzr1t_l9r_go_relaxed.owl	(8R,9Z,12Z)-8-hydroperoxy-9,12-octadecadienoate mutase ((7S,8S,9Z,12Z)-5,8-dihydroxy-9,12-octadecadienoate-forming) activity|8-hydroperoxide isomerase activity|linoleate diol synthase activity				RHEA:25399|EC:5.4.4.6|KEGG_REACTION:R07062|MetaCyc:1.13.11.44-RXN									molecular_function											owl:Class	
GO:0018171	biolink:NamedThing	peptidyl-cysteine oxidation	The oxidation of peptidyl-cysteine to peptidyl-L-cysteine sulfinic acid or peptidyl-L-cysteine sulfenic acid.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0205|RESID:AA0262									biological_process											owl:Class	
GO:2000388	biolink:NamedThing	positive regulation of antral ovarian follicle growth	Any process that activates or increases the frequency, rate or extent of antral ovarian follicle growth.	tmpzr1t_l9r_go_relaxed.owl								yaf	2011-02-16T04:54:01Z					biological_process											owl:Class	
GO:0052811	biolink:NamedThing	1-phosphatidylinositol-3-phosphate 4-kinase activity	Catalysis of the reaction: a 1-phosphatidyl-1D-myo-inositol 3-phosphate + ATP = a 1-phosphatidyl-1D-myo-inositol 3,4-bisphosphate + ADP + 2 H(+).	tmpzr1t_l9r_go_relaxed.owl	ATP:1-phosphatidyl-1D-myo-inositol-3-phosphate 4-phosphotransferase activity|phosphatidylinositol 3-phosphate 4-kinase activity				RHEA:63688|Reactome:R-HSA-1676145			ai	2011-10-21T03:47:58Z					molecular_function											owl:Class	
GO:0042258	biolink:NamedThing	molybdenum incorporation via L-serinyl molybdopterin guanine dinucleotide	The incorporation of molybdenum into a protein via L-serinyl molybdopterin guanine dinucleotide.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0319									biological_process											owl:Class	
GO:0015527	biolink:NamedThing	glycerol-phosphate:inorganic phosphate antiporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glycerol phosphate(out) + inorganic phosphate(in) = glycerol phosphate(in) + inorganic phosphate(out).	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0062034	biolink:NamedThing	L-pipecolic acid biosynthetic process	The chemical reactions and pathways resulting in the formation of L-pipecolic acid, a metabolite of lysine.	tmpzr1t_l9r_go_relaxed.owl	L-pipecolate biosynthetic process							dph	2018-04-24T12:19:36Z					biological_process											owl:Class	
GO:0000214	biolink:NamedThing	tRNA-intron endonuclease complex	A protein complex that catalyzes the endonucleolytic cleavage of pre-tRNA, producing 5'-hydroxyl and 2',3'-cyclic phosphate termini, and specifically removing the intron.	tmpzr1t_l9r_go_relaxed.owl	SEN complex|tRNA splicing endonuclease complex													cellular_component											owl:Class	
GO:2001294	biolink:NamedThing	malonyl-CoA catabolic process	The chemical reactions and pathways resulting in the breakdown of malonyl-CoA, the S-malonyl derivative of coenzyme A.	tmpzr1t_l9r_go_relaxed.owl	malonyl-CoA degradation|malonyl-CoA catabolism|malonyl-CoA breakdown							pr	2012-02-14T02:23:17Z					biological_process											owl:Class	
GO:0047897	biolink:NamedThing	formate-dihydrofolate ligase activity	Catalysis of the reaction: 7,8-dihydrofolate + ATP + formate = 10-formyldihydrofolate + ADP + H(+) + phosphate.	tmpzr1t_l9r_go_relaxed.owl	formyl dihydrofolate synthase activity|formate:dihydrofolate ligase (ADP-forming)|dihydrofolate formyltransferase activity				RHEA:24328|MetaCyc:FORMATE--DIHYDROFOLATE-LIGASE-RXN|EC:6.3.4.17|KEGG_REACTION:R02238									molecular_function											owl:Class	
GO:0072711	biolink:NamedThing	cellular response to hydroxyurea	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydroxyurea stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to HU							mah	2012-04-11T04:15:56Z					biological_process											owl:Class	
GO:0048241	biolink:NamedThing	epinephrine transport	The directed movement of epinephrine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	adrenaline transport													biological_process											owl:Class	
GO:0034175	biolink:NamedThing	regulation of toll-like receptor 12 signaling pathway	Any process that modulates the frequency, rate, or extent of toll-like receptor 12 signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	regulation of toll-like receptor 12 signalling pathway|regulation of TLR12 signaling pathway													biological_process											owl:Class	
GO:0030884	biolink:NamedThing	exogenous lipid antigen binding	Binding to an exogenous lipid antigen (examples include microbial lipids and glycolipids).	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0061513	biolink:NamedThing	glucose 6-phosphate:inorganic phosphate antiporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucose 6-phosphate(out) + inorganic phosphate(in) = glucose 6-phosphate(in) + inorganic phosphate(out).	tmpzr1t_l9r_go_relaxed.owl	glucose 6-phosphate:phosphate antiporter activity				Reactome:R-HSA-198513|Reactome:R-HSA-3257122|Reactome:R-HSA-3229118			dph	2013-04-17T08:47:40Z			GO:0008524		molecular_function											owl:Class	
GO:0071237	biolink:NamedThing	cellular response to bacteriocin	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bacteriocin stimulus. A bacteriocin is a protein substance released by certain bacteria that kills but does not lyse closely related strains of bacteria. Specific bacteriocins attach to specific receptors on cell walls and induce specific metabolic block, e.g. cessation of nucleic acid or protein synthesis of oxidative phosphorylation.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-12-03T02:25:43Z					biological_process											owl:Class	
GO:0008855	biolink:NamedThing	exodeoxyribonuclease VII activity	Catalysis of the exonucleolytic cleavage in either 5' to 3' or 3' to 5' direction to yield 5'-phosphomononucleotides.	tmpzr1t_l9r_go_relaxed.owl	exonuclease VII activity|E. coli exonuclease VII|endodeoxyribonuclease VII|E. coli exonuclease VII activity|Escherichia coli exonuclease VII				EC:3.1.11.6|MetaCyc:3.1.11.6-RXN									molecular_function											owl:Class	
GO:0033553	biolink:NamedThing	rDNA heterochromatin	A region of heterochromatin located at the rDNA repeats in a chromosome.	tmpzr1t_l9r_go_relaxed.owl	ribosomal DNA heterochromatin|ribosomal DNA heterochromatin of cell nucleus|nuclear rDNA heterochromatin|ribosomal DNA heterochromatin of nucleus											GO:1902377		cellular_component											owl:Class	
GO:0106094	biolink:NamedThing	nuclear membrane microtubule tethering complex	A nuclear membrane protein complex which connects the nuclear outer and inner membranes together, and links thereby links the nuclear lumen to cytoplasmic microtubules.	tmpzr1t_l9r_go_relaxed.owl		nuclear membrane microtubule tethering complex						hjd	2018-02-02T18:58:35Z					cellular_component											owl:Class	
GO:0046080	biolink:NamedThing	dUTP metabolic process	The chemical reactions and pathways involving dUTP, deoxyuridine (5'-)triphosphate.	tmpzr1t_l9r_go_relaxed.owl	dUTP metabolism													biological_process											owl:Class	
GO:0097451	biolink:NamedThing	glial limiting end-foot	Terminal process of astrocyte that extends to the surface of the central nervous system. Together, glial limiting end-feet form the glial limiting membrane or glia limitans.	tmpzr1t_l9r_go_relaxed.owl	glial limiting endfoot				NIF_Subcellular:sao181458425			pr	2012-12-17T13:36:34Z					cellular_component											owl:Class	
GO:0097450	biolink:NamedThing	astrocyte end-foot	Terminal process of astrocyte abutting non-neuronal surfaces in the brain.	tmpzr1t_l9r_go_relaxed.owl	astrocyte endfoot				NIF_Subcellular:sao388182739			pr	2012-12-17T13:33:55Z					cellular_component											owl:Class	
GO:0031975	biolink:NamedThing	envelope	A multilayered structure surrounding all or part of a cell; encompasses one or more lipid bilayers, and may include a cell wall layer; also includes the space between layers.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0034562	biolink:NamedThing	2,2-bis(4-hydroxyphenyl)-1-propanol hydroxylase activity	Catalysis of the reaction: 2,2-bis(4-hydroxyphenyl)-1-propanol + NADH + H+ + O2 = 2,3-bis(4-hydroxyphenyl)-1,2-propanediol + NAD+ + H2O.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0864									molecular_function											owl:Class	
GO:0075134	biolink:NamedThing	induction by symbiont of host calcium or calmodulin-mediated signal transduction	Any process in which the symbiont activates, maintains or increases the frequency, rate or extent of calcium or calmodulin-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	positive regulation by symbiont of host Ca++ or calmodulin-mediated signal transduction|positive regulation by symbiont of host calcium or calmodulin-mediated signal transduction					Note that this term is used to annotate gene products of the symbiont. To annotate host gene products, consider the biological process term "positive regulation by host of symbiont calcium or calmodulin-mediated signal transduction ; GO:0075104".								biological_process											owl:Class	
GO:0051380	biolink:NamedThing	norepinephrine binding	Binding to norepinephrine, (3,4-dihydroxyphenyl-2-aminoethanol), a hormone secreted by the adrenal medulla and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts of the CNS. It is also the biosynthetic precursor of epinephrine.	tmpzr1t_l9r_go_relaxed.owl	noradrenaline binding													molecular_function											owl:Class	
GO:1901338	biolink:NamedThing	catecholamine binding	Binding to catecholamine.	tmpzr1t_l9r_go_relaxed.owl								bf	2012-09-03T14:08:44Z					molecular_function											owl:Class	
GO:0004019	biolink:NamedThing	adenylosuccinate synthase activity	Catalysis of the reaction: L-aspartate + GTP + IMP = N(6)-(1,2-dicarboxyethyl)-AMP + GDP + 3 H(+) + phosphate.	tmpzr1t_l9r_go_relaxed.owl	adenylosuccinate synthetase activity|IMP--aspartate ligase activity|succinoadenylic kinosynthetase activity|IMP:L-aspartate ligase (GDP-forming)|succino-AMP synthetase activity				Reactome:R-HSA-111524|KEGG_REACTION:R01135|EC:6.3.4.4|RHEA:15753|MetaCyc:ADENYLOSUCCINATE-SYNTHASE-RXN									molecular_function											owl:Class	
GO:2001136	biolink:NamedThing	negative regulation of endocytic recycling	Any process that stops, prevents or reduces the frequency, rate or extent of endocytic recycling.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of retrograde transport of endocytic vesicles							kmv	2011-10-14T03:34:43Z					biological_process											owl:Class	
GO:0070275	biolink:NamedThing	aerobic ammonia oxidation to nitrite via pyruvic oxime	The metabolic process in which ammonia (NH3) is oxidized to nitrite (NO2) in the presence of oxygen. Hydroxylamine is produced enzymatically, and, in the presence of pyruvate, forms pyruvic oxime in a spontaneous, non-enzymatic reaction; pyruvic oxime is then converted to nitrite.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:PWY-2242									biological_process											owl:Class	
GO:0019329	biolink:NamedThing	ammonia oxidation	The chemical reactions and pathways by which ammonia or ammonium is converted to molecular nitrogen or another nitrogen compound, with accompanying loss of electrons.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0098804	biolink:NamedThing	non-motile cilium membrane	The portion of the plasma membrane surrounding a non-motile cilium.	tmpzr1t_l9r_go_relaxed.owl	nonmotile primary cilium membrane													cellular_component											owl:Class	
GO:0002788	biolink:NamedThing	regulation of antifungal peptide production	Any process that modulates the frequency, rate, or extent of antifungal peptide production.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0002680	biolink:NamedThing	pro-T cell lineage commitment	The process in which a lymphoid progenitor cell becomes committed to becoming a pro-T cell.	tmpzr1t_l9r_go_relaxed.owl	pro-T lymphocyte lineage commitment|pro-T cell fate commitment|pro-T lymphocyte fate commitment													biological_process											owl:Class	
GO:0008786	biolink:NamedThing	allose 6-phosphate isomerase activity	Catalysis of the reaction: D-allose-6-phosphate = D-allulose-6-phosphate.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN0-303|RHEA:28430									molecular_function											owl:Class	
GO:0002566	biolink:NamedThing	somatic diversification of immune receptors via somatic mutation	The process in which immune receptor genes are diversified through somatic mutation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0046419	biolink:NamedThing	octopine metabolic process	The chemical reactions and pathways involving octopine, (N-(1-carboxy-4-guanidinobutyl)-L-alanine), an amino acid derived opine.	tmpzr1t_l9r_go_relaxed.owl	octopine metabolism													biological_process											owl:Class	
GO:0002752	biolink:NamedThing	cell surface pattern recognition receptor signaling pathway	Any series of molecular signals generated as a consequence of a cell surface pattern recognition receptor (PRR) binding to one of its physiological ligands. PRRs bind pathogen-associated molecular pattern (PAMPs), structures conserved among microbial species.	tmpzr1t_l9r_go_relaxed.owl	cell surface PAMP receptor signaling pathway|cell surface pattern recognition receptor signalling pathway|cell surface PRR signaling pathway|cell surface pathogen receptor signaling pathway	https://github.com/geneontology/go-ontology/issues/18588												biological_process											owl:Class	
GO:0036151	biolink:NamedThing	phosphatidylcholine acyl-chain remodeling	Remodeling the acyl chains of phosphatidylcholine, through sequential deacylation and re-acylation reactions, to generate phosphatidylcholine containing different types of fatty acid acyl chains.	tmpzr1t_l9r_go_relaxed.owl								bf	2012-03-14T01:54:13Z					biological_process											owl:Class	
GO:0071732	biolink:NamedThing	cellular response to nitric oxide	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitric oxide stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-03-17T04:12:52Z					biological_process											owl:Class	
GO:0044269	biolink:NamedThing	glycerol ether catabolic process	The chemical reactions and pathways resulting in the breakdown of glycerol ethers, any anhydride formed between two organic hydroxy compounds, one of which is glycerol.	tmpzr1t_l9r_go_relaxed.owl	glycerol ether degradation|glycerol ether catabolism|glycerol ether breakdown													biological_process											owl:Class	
GO:0001065	biolink:NamedThing	mitochondrial single subunit type RNA polymerase activity	Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template that contains a single-subunit-type mitochondrial RNA polymerase-specific promoter to direct initiation and catalyses DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'.	tmpzr1t_l9r_go_relaxed.owl								krc	2010-10-19T03:50:51Z					molecular_function											owl:Class	
GO:0097426	biolink:NamedThing	glial filament	An intermediate filament composed of glial fibrillary acidic protein (GFAP) and found in astrocytes.	tmpzr1t_l9r_go_relaxed.owl					NIF_Subcellular:sao1863852493			pr	2012-11-07T14:59:55Z					cellular_component											owl:Class	
GO:0019114	biolink:NamedThing	catechol dioxygenase activity	Catalysis of the reaction: catechol + O2 = a muconate.	tmpzr1t_l9r_go_relaxed.owl					EC:1.13.11.-									molecular_function											owl:Class	
GO:0097504	biolink:NamedThing	Gemini of coiled bodies	Nuclear bodies frequently found near or associated with Cajal bodies (also called coiled bodies or CBs). Gemini of coiled bodies, or 'gems', are similar in size and shape to CBs, and often indistinguishable under the microscope. Unlike CBs, gems do not contain small nuclear ribonucleoproteins (snRNPs); they contain a protein called survivor of motor neurons (SMN) whose function relates to snRNP biogenesis. Gems are believed to assist CBs in snRNP biogenesis, and to play a role in the etiology of spinal muscular atrophy (SMA).	tmpzr1t_l9r_go_relaxed.owl	Gems							pr	2013-09-24T15:20:12Z					cellular_component											owl:Class	
GO:0002045	biolink:NamedThing	regulation of cell adhesion involved in intussusceptive angiogenesis	The process that modulates the frequency, rate or extent of attachment of a blood vessel endothelial cell to another cell or to the extracellular matrix involved in intussusceptive angiogenesis.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0046529	biolink:NamedThing	imaginal disc fusion, thorax closure	The joining of the parts of the wing imaginal discs, giving rise to the adult thorax.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0008056	biolink:NamedThing	ocellus development	The process whose specific outcome is the progression of the ocellus over time, from its formation to the mature structure. The ocellus is a simple visual organ of insects.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1990816	biolink:NamedThing	vacuole-mitochondrion membrane contact site	A zone of apposition between the vacuolar membrane and the mitochondrial outer membrane, important for transfer of lipids between the two organelles.	tmpzr1t_l9r_go_relaxed.owl	vacuole and mitochondria patch|vCLAMP							mcc	2015-07-29T21:06:41Z					cellular_component											owl:Class	
GO:0016059	biolink:NamedThing	deactivation of rhodopsin mediated signaling	The process of restoring the photoreceptor cell to its unexcited state after termination of the stimulus (photon).	tmpzr1t_l9r_go_relaxed.owl	deactivation of rhodopsin mediated signalling|rod response recovery													biological_process											owl:Class	
GO:0004068	biolink:NamedThing	aspartate 1-decarboxylase activity	Catalysis of the reaction: L-aspartate = beta-alanine + CO2.	tmpzr1t_l9r_go_relaxed.owl	L-aspartate 1-carboxy-lyase (beta-alanine-forming)|L-aspartate alpha-decarboxylase activity|aspartic alpha-decarboxylase|aspartate alpha-decarboxylase activity|L-aspartate 1-carboxy-lyase activity				MetaCyc:ASPDECARBOX-RXN|EC:4.1.1.11|RHEA:19497|MetaCyc:PWY-5155									molecular_function											owl:Class	
GO:0102171	biolink:NamedThing	DMNT synthase activity	Catalysis of the reaction: H+ + (3S,6E)-nerolidol + NADPH + O2 <=> (E)-4,8-dimethyl-1,3,7-nonatriene + buten-2-one + NADP + 2 H2O.	tmpzr1t_l9r_go_relaxed.owl					RHEA:55424|MetaCyc:RXN-11911									molecular_function											owl:Class	
GO:0080005	biolink:NamedThing	photosystem stoichiometry adjustment	Adjustment of Photosystem I/Photosystem II ratio in response to light conditions. The function of photosystem stoichiometry adjustment is to compensate for any deficiency in energy conversion at either photosystem I or photosystem II by increasing the quantity the photosystem that will otherwise become the rate-limiting to overall photosynthesis.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1990416	biolink:NamedThing	cellular response to brain-derived neurotrophic factor stimulus	A process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a brain-derived neurotrophic factor stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to BDNF stimulus							sl	2014-07-11T17:55:59Z					biological_process											owl:Class	
GO:0070708	biolink:NamedThing	RNA cytidine insertion	The modification of an RNA molecule by insertion of a cytidine nucleotide.	tmpzr1t_l9r_go_relaxed.owl	RNA C insertion							mah	2009-06-08T04:52:49Z					biological_process											owl:Class	
GO:0031709	biolink:NamedThing	gastrin-releasing peptide receptor binding	Binding to a gastrin-releasing peptide receptor.	tmpzr1t_l9r_go_relaxed.owl	GRP receptor binding|gastrin-releasing peptide receptor ligand													molecular_function											owl:Class	
GO:0048810	biolink:NamedThing	female analia morphogenesis	The process in which the anatomical structures of the analia of the female are generated and organized. The analia is the posterior-most vertral appendage that develops from the genital disc. An example of this process is found in Drosophila melanogaster.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0046701	biolink:NamedThing	insecticide catabolic process	The chemical reactions and pathways resulting in the breakdown of insecticides, chemicals used to kill insects.	tmpzr1t_l9r_go_relaxed.owl	insecticide degradation|insecticide breakdown|insecticide catabolism													biological_process											owl:Class	
GO:0052916	biolink:NamedThing	23S rRNA (guanine(1835)-N(2))-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + guanosine(1835) in 23S rRNA = N(2)-methylguanosine(1835) in 23S rRNA + S-adenosyl-L-homocysteine.	tmpzr1t_l9r_go_relaxed.owl					RHEA:42744|MetaCyc:RXN-11635|KEGG_REACTION:R07234|EC:2.1.1.174									molecular_function											owl:Class	
GO:1990477	biolink:NamedThing	MTREC complex	Protein complex formed by an RNA binding protein Red1, an RNA helicase Mtl1, Red5, Rmn1, Iss10/Pir1, and Ars2/Pir2. This complex is required for the recruitment of the nuclear exosome to Mmi1 nuclear focus. It is likely related to the human CBCN complex. This complex is also known as RNA silencing (NURS) complex.	tmpzr1t_l9r_go_relaxed.owl	Mtl1-Red1 core complex|PAXT complex|NURS complex	https://github.com/geneontology/go-ontology/issues/19059|https://github.com/geneontology/go-ontology/issues/21207				An example of this is the complex formed by Red1 and Mtl1 in S. pombe (UniProt symbols Q9UTR8 and O13799 respectively) in PMID:24210919 (inferred from direct assay).		mah	2014-03-24T13:30:52Z			GO:1990345		cellular_component											owl:Class	
GO:0034510	biolink:NamedThing	centromere separation	The cell cycle process in which centromeres are physically detached from each other during chromosome separation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0008107	biolink:NamedThing	galactoside 2-alpha-L-fucosyltransferase activity	Catalysis of the reaction: GDP-L-fucose + beta-D-galactosyl-R = GDP + alpha-L-fucosyl-(1,2)-beta-D-galactosyl-R.	tmpzr1t_l9r_go_relaxed.owl	guanosine diphosphofucose-galactoside 2-L-fucosyltransferase activity|secretor-type beta-galactoside alpha1->2 fucosyltransferase activity|GDP fucose-lactose fucosyltransferase activity|beta-galactoside alpha-1->2 fucosyltransferase activity|H-gene-encoded beta-galactoside alpha1->2 fucosyltransferase activity|secretor-type beta-galactoside alpha-1->2 fucosyltransferase activity|guanosine diphosphofucose-galactosylacetylglucosaminylgalactosyl-glucosylceramide alpha-L-fucosyltransferase activity|alpha(1,2)-L-fucosyltransferase activity|GDP-L-fucose:lactose fucosyltransferase activity|alpha-2-fucosyltransferase activity|guanosine diphosphofucose-lactose fucosyltransferase activity|galactoside 2-L-fucosyltransferase activity|GDP-beta-L-fucose:beta-D-galactosyl-R 2-alpha-L-fucosyltransferase activity|blood group H alpha-2-fucosyltransferase activity|beta-galactoside alpha1->2 fucosyltransferase activity|guanosine diphosphofucose-galactosylacetylglucosaminylgalactosylglucosylceramide alpha-L-fucosyltransferase activity|guanosine diphosphofucose-beta-D-galactosyl-alpha-2-L-fucosyltransferase activity|guanosine diphosphofucose-glycoprotein 2-alpha-L-fucosyltransferase activity|blood-group substance H-dependent fucosyltransferase activity|guanosine diphospho-L-fucose-lactose fucosyltransferase activity|alpha-2-L-fucosyltransferase activity|guanosine diphosphofucose-glycoprotein 2-alpha-fucosyltransferase activity|alpha-(1->2)-L-fucosyltransferase activity|H-gene-encoded beta-galactoside alpha-1->2 fucosyltransferase activity				Reactome:R-HSA-9603982|Reactome:R-HSA-9603983|MetaCyc:GALACTOSIDE-2-L-FUCOSYLTRANSFERASE-RXN|RHEA:50664|EC:2.4.1.69|Reactome:R-HSA-9036987									molecular_function											owl:Class	
GO:0031127	biolink:NamedThing	alpha-(1,2)-fucosyltransferase activity	Catalysis of the transfer of an L-fucosyl group from GDP-beta-L-fucose to an acceptor molecule to form an alpha-(1->2) linkage.	tmpzr1t_l9r_go_relaxed.owl	alpha-1,2-fucosyltransferase activity|alpha-(1->2)-fucosyltransferase activity													molecular_function											owl:Class	
GO:0042185	biolink:NamedThing	m-xylene catabolic process	The chemical reactions and pathways resulting in the breakdown of m-xylene, 1,3-dimethylbenzene, a colorless, liquid aromatic hydrocarbon.	tmpzr1t_l9r_go_relaxed.owl	meta-xylene catabolic process|meta-xylene catabolism|m-xylene catabolism|m-xylene degradation|m-xylene breakdown				MetaCyc:PWY-142									biological_process											owl:Class	
GO:0018949	biolink:NamedThing	m-xylene metabolic process	The chemical reactions and pathways involving m-xylene, (1,3-dimethylbenzene) a colorless, liquid aromatic hydrocarbon.	tmpzr1t_l9r_go_relaxed.owl	meta-xylene metabolism|m-xylene metabolism|meta-xylene metabolic process				UM-BBD_pathwayID:mxy									biological_process											owl:Class	
GO:0070290	biolink:NamedThing	N-acylphosphatidylethanolamine-specific phospholipase D activity	Catalysis of the release of N-acylethanolamine from N-acyl-phosphatidylethanolamine (NAPE) to generate N-acylethanolamine (NAE).	tmpzr1t_l9r_go_relaxed.owl	N-acyl-phosphatidylethanolamine-specific phospholipase D activity|NAPE-specific phospholipase D activity				EC:3.1.4.4|Reactome:R-HSA-2466831									molecular_function											owl:Class	
GO:0047777	biolink:NamedThing	(S)-citramalyl-CoA lyase activity	Catalysis of the reaction: (3S)-citramalyl-CoA = acetyl-CoA + pyruvate.	tmpzr1t_l9r_go_relaxed.owl	(3S)-citramalyl-CoA lyase activity|citramalyl-CoA lyase activity|(3S)-citramalyl-CoA pyruvate-lyase activity|(+)-CMA-CoA lyase activity|citramalyl coenzyme A lyase activity|(3S)-citramalyl-CoA pyruvate-lyase (acetyl-CoA-forming)				RHEA:22612|KEGG_REACTION:R00237|MetaCyc:CITRAMALYL-COA-LYASE-RXN|EC:4.1.3.25									molecular_function											owl:Class	
GO:0040019	biolink:NamedThing	positive regulation of embryonic development	Any process that activates or increases the frequency, rate or extent of embryonic development.	tmpzr1t_l9r_go_relaxed.owl	upregulation of embryonic development|up-regulation of embryonic development|up regulation of embryonic development|activation of embryonic development|stimulation of embryonic development													biological_process											owl:Class	
GO:0016435	biolink:NamedThing	rRNA (guanine) methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing methylguanine.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0008403	biolink:NamedThing	25-hydroxycholecalciferol-24-hydroxylase activity	Catalysis of the hydroxylation of C-24 of 25-hydroxycholecalciferol (25-hydroxyvitamin D3) to form 24(R),25-dihydroxycholecalciferol.	tmpzr1t_l9r_go_relaxed.owl	25-hydroxyvitamin D3 24-hydroxylase activity|cytochrome P450 CYP24											GO:0030344		molecular_function											owl:Class	
GO:0070611	biolink:NamedThing	histone methyltransferase activity (H3-R2 specific)	Catalysis of the reaction: S-adenosyl-L-methionine + (histone H3)-arginine (position 2) = S-adenosyl-L-homocysteine + (histone H3)-N-methyl-arginine (position 2). This reaction is the addition of a methyl group to arginine at position 2 of histone H3.	tmpzr1t_l9r_go_relaxed.owl	histone methylase activity (H3-R2 specific)|histone-arginine N-methyltransferase activity (H3-R2 specific)							mah	2009-04-29T02:04:44Z					molecular_function											owl:Class	
GO:0036195	biolink:NamedThing	muscle cell projection membrane	The portion of the plasma membrane surrounding a muscle cell projection.	tmpzr1t_l9r_go_relaxed.owl								bf	2012-04-20T10:21:51Z					cellular_component											owl:Class	
GO:0050265	biolink:NamedThing	RNA uridylyltransferase activity	Catalysis of the reaction: UTP + RNA(n) = diphosphate + RNA(n+1).	tmpzr1t_l9r_go_relaxed.owl	UTP:RNA uridylyltransferase activity|polynucleotide uridylyltransferase activity|terminal uridylyltransferase activity|poly(U) polymerase activity|TUT activity				Reactome:R-HSA-8941312|MetaCyc:RNA-URIDYLYLTRANSFERASE-RXN|RHEA:14785|EC:2.7.7.52									molecular_function											owl:Class	
GO:0061661	biolink:NamedThing	FAT10 ligase activity	Catalysis of the transfer of FAT10 to a substrate protein via the reaction X-FAT10 + S --> X + S-FAT10, where X is either an E2 or E3 enzyme, the X-FAT10 linkage is a thioester bond, and the S-FAT10 linkage is an isopeptide bond between the C-terminal glycine of FAT10 and the epsilon-amino group of lysine residues in the substrate.	tmpzr1t_l9r_go_relaxed.owl	E3							dph	2014-11-06T13:53:10Z					molecular_function											owl:Class	
GO:1903801	biolink:NamedThing	L-leucine import across plasma membrane	The directed movement of L-leucine from outside of a cell, across the plasma membrane and into the cytosol.	tmpzr1t_l9r_go_relaxed.owl	leucine import|L-leucine uptake|L-leucine import into cell|leucine uptake|L-leucine import							mah	2015-01-16T14:34:46Z			GO:0060356		biological_process											owl:Class	
GO:0021688	biolink:NamedThing	cerebellar molecular layer formation	The process that gives rise to the cerebellar molecular layer. This process pertains to the initial formation of a structure from unspecified parts. The molecular layer is the outermost layer of the cerebellar cortex. It contains the parallel fibers of the granule cells, interneurons such as stellate and basket cells, and the dendrites of the underlying Purkinje cells.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0046569	biolink:NamedThing	glyoxal oxidase activity	Catalysis of the reaction: glyoxal + O2 + H2O = glyoxalate + H2O2.	tmpzr1t_l9r_go_relaxed.owl	GLOX													molecular_function											owl:Class	
GO:0008715	biolink:NamedThing	CDP-diacylglycerol diphosphatase activity	Catalysis of the reaction: CDP-diacylglycerol + H(2)O = a phosphatidate + CMP + 2 H(+).	tmpzr1t_l9r_go_relaxed.owl	CDP-diacylglycerol phosphatidylhydrolase activity|CDP-diacylglycerol pyrophosphatase activity|cytidine diphosphodiacylglycerol pyrophosphatase activity|CDP diacylglycerol hydrolase activity				MetaCyc:CDPDIGLYPYPHOSPHA-RXN|KEGG_REACTION:R01797|RHEA:15221|EC:3.6.1.26									molecular_function											owl:Class	
GO:0097416	biolink:NamedThing	Lewy body-like hyaline inclusion	Cytoplasmic inclusion found in neurons. It consists of filaments and granular materials, exhibits a dense core with a rough peripheral halo and lacks a limiting membrane. The filaments of these inclusions are composed of approximately 15-25 nm granule-coated fibrils in association with normal 10-nm neurofilaments.	tmpzr1t_l9r_go_relaxed.owl	LBHI				NIF_Subcellular:nlx_subcell_20090105			pr	2012-11-06T16:46:15Z					cellular_component											owl:Class	
GO:0051659	biolink:NamedThing	maintenance of mitochondrion location	Any process in which a mitochondrion is maintained in a specific location within a cell and prevented from moving elsewhere.	tmpzr1t_l9r_go_relaxed.owl	maintenance of mitochondrion localization|maintenance of mitochondria localization													biological_process											owl:Class	
GO:0001591	biolink:NamedThing	dopamine neurotransmitter receptor activity, coupled via Gi/Go	Combining with the neurotransmitter dopamine and activating adenylate cyclase via coupling to Gi/Go to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	dopamine D4 receptor activity|dopamine D3 receptor activity|dopamine D2 receptor activity											GO:0001592|GO:0001593|GO:0001670		molecular_function											owl:Class	
GO:0046811	biolink:NamedThing	histone deacetylase inhibitor activity	Binds to and stops, prevents or reduces the activity of histone deacetylase, which catalyzes of the removal of acetyl groups from histones, proteins complexed to DNA in chromatin and chromosomes.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0071965	biolink:NamedThing	multicellular organismal locomotion	Locomotion in a multicellular organism, i.e. self-propelled movement of a multicellular organism from one location to another.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-10-14T10:34:35Z					biological_process											owl:Class	
GO:0018606	biolink:NamedThing	benzenesulfonate dioxygenase activity	Catalysis of the reaction: toluene-4-sulfonate + NADH + O2 + H+ = NAD+ + HSO3(-) + 4-methylcatechol.	tmpzr1t_l9r_go_relaxed.owl	benzenesulphonate dioxygenase activity				EC:1.14.12.-|UM-BBD_reactionID:r0295									molecular_function											owl:Class	
GO:0008213	biolink:NamedThing	protein alkylation	The addition of an alkyl group to a protein amino acid. Alkyl groups are derived from alkanes by removal of one hydrogen atom.	tmpzr1t_l9r_go_relaxed.owl	protein amino acid alkylation													biological_process											owl:Class	
GO:0047639	biolink:NamedThing	alcohol oxidase activity	Catalysis of the reaction: a primary alcohol + O2 = an aldehyde + H2O2.	tmpzr1t_l9r_go_relaxed.owl	ethanol oxidase activity|alcohol:oxygen oxidoreductase activity|AOX activity				MetaCyc:ALCOHOL-OXIDASE-RXN|EC:1.1.3.13|RHEA:19829	Note that the enzyme alcohol oxidase also has methanol oxidase activity (GO:0046563).								molecular_function											owl:Class	
GO:0009317	biolink:NamedThing	acetyl-CoA carboxylase complex	A protein complex that catalyzes the first step in long-chain fatty acid biosynthesis. For example, in E. coli the complex is heterohexameric and composed of biotin carbonyl carrier protein, biotin carboxylase and the acetate CoA-transferase complex.	tmpzr1t_l9r_go_relaxed.owl	ACCase complex													cellular_component											owl:Class	
GO:0035228	biolink:NamedThing	negative regulation of glutamate-cysteine ligase activity	Any process that stops or reduces the activity of the enzyme glutamate-cysteine ligase.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of glutamate-cysteine ligase activity|downregulation of glutamate-cysteine ligase activity|inhibition of glutamate-cysteine ligase activity|down regulation of glutamate-cysteine ligase activity													biological_process											owl:Class	
GO:0047114	biolink:NamedThing	kynurenate-7,8-dihydrodiol dehydrogenase activity	Catalysis of the reaction: 7,8-dihydro-7,8-dihydroxykynurenate + NAD(+) = 7,8-dihydroxykynurenate + H(+) + NADH.	tmpzr1t_l9r_go_relaxed.owl	7,8-dihydro-7,8-dihydroxykynurenate:NAD+ oxidoreductase activity|7,8-dihydro-7,8-dihydroxykynurenate dehydrogenase activity|7,8-dihydroxykynurenic acid 7,8-diol dehydrogenase activity				KEGG_REACTION:R03251|EC:1.3.1.18|RHEA:22248|MetaCyc:1.3.1.18-RXN									molecular_function											owl:Class	
GO:0031586	biolink:NamedThing	negative regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity	Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of the inositol 1,4,5-trisphosphate-sensitive calcium-release channel.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of IP3 receptor activity|down regulation of IP3 receptor activity|inhibition of IP3 receptor activity|negative regulation of IP3 receptor activity|negative regulation of inositol 1,4,5-trisphosphate receptor activity|downregulation of IP3 receptor activity													biological_process											owl:Class	
GO:0033375	biolink:NamedThing	protease localization to T cell secretory granule	Any process in which a protease is transported to, or maintained in, a location within a secretory granule in a T cell.	tmpzr1t_l9r_go_relaxed.owl	protease localization in T cell secretory granule|protease localization in T-cell secretory granule|protease localization in T-lymphocyte secretory granule|protease localization in T lymphocyte secretory granule|protease localisation in T cell secretory granule													biological_process											owl:Class	
GO:1902362	biolink:NamedThing	melanocyte apoptotic process	Any apoptotic process in a melanocyte, the main structural component of the epidermis.	tmpzr1t_l9r_go_relaxed.owl	melanophore apoptosis|melanophore apoptotic process|melanocyte apoptosis							pr	2013-08-15T16:35:45Z					biological_process											owl:Class	
GO:0102235	biolink:NamedThing	1-penten-3-one reductase activity	Catalysis of the reaction: 1-penten-3-one + NADPH + H+ <=> 1-pentan-3-one + NADP.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-12295									molecular_function											owl:Class	
GO:0019862	biolink:NamedThing	IgA binding	Binding to an immunoglobulin of an IgA isotype.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0039588	biolink:NamedThing	suppression by virus of host antigen processing and presentation	Any viral process that inhibits a host antigen-presenting cell expressing a peptide antigen on its cell surface in association with an MHC protein complex.	tmpzr1t_l9r_go_relaxed.owl	inhibition of host proteasome antigen processing by virus				VZ:815			bf	2012-05-04T04:34:52Z					biological_process											owl:Class	
GO:0061565	biolink:NamedThing	dAMP phosphorylation	The process of introducing a phosphate group into dAMP, deoxyadenosine monophosphate, to produce dADP. Addition of two phosphate groups produces dATP.	tmpzr1t_l9r_go_relaxed.owl								dph	2013-08-01T12:50:38Z					biological_process											owl:Class	
GO:1901789	biolink:NamedThing	benzoyl-CoA biosynthetic process	The chemical reactions and pathways resulting in the formation of benzoyl-CoA.	tmpzr1t_l9r_go_relaxed.owl	benzoyl-CoA biosynthesis|benzoyl-CoA anabolism|benzoyl-CoA synthesis|benzoyl-CoA formation							yaf	2013-01-16T11:14:03Z					biological_process											owl:Class	
GO:1903840	biolink:NamedThing	response to arsenite(3-)	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an arsenite(3-) stimulus.	tmpzr1t_l9r_go_relaxed.owl								mr	2015-01-22T19:49:25Z					biological_process											owl:Class	
GO:0035211	biolink:NamedThing	spermathecum morphogenesis	The process in which the anatomical structures of a spermathecum, a sperm storage organ, are generated and organized. Paired spermathecae lie at the anterior end of the insect uterus on the dorsal side. Each spermatheca consists of an oval shaped capsule, connected to the uterus by a spermathecal stalk.	tmpzr1t_l9r_go_relaxed.owl						See also the fly_anatomy.ontology term 'spermathecum ; FBbt:00004921'.								biological_process											owl:Class	
GO:1905712	biolink:NamedThing	cellular response to phosphatidylethanolamine	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a phosphatidylethanolamine stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to phosphatidylethanolamines|cellular response to phosphatidyl(amino)ethanols|cellular response to PtdEtn|cellular response to PE							sl	2016-11-21T19:55:40Z					biological_process											owl:Class	
GO:0018478	biolink:NamedThing	malonate-semialdehyde dehydrogenase (acetylating) activity	Catalysis of the reaction: 3-oxopropanoate + CoA + NADP+ = acetyl-CoA + CO2 + NADPH + H+.	tmpzr1t_l9r_go_relaxed.owl	3-oxopropanoate:NAD(P)+ oxidoreductase (decarboxylating, CoA-acetylating)|malonic semialdehyde oxidative decarboxylase activity				EC:1.2.1.18|RHEA:22988|MetaCyc:1.2.1.18-RXN									molecular_function											owl:Class	
GO:0010626	biolink:NamedThing	negative regulation of Schwann cell proliferation	Any process that decreases the frequency or extent of the multiplication or reproduction of Schwann cells, resulting in the expansion of their population. Schwann cells are a type of glial cell in the peripheral nervous system.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1904489	biolink:NamedThing	regulation of reactive oxygen species metabolic process by negative regulation of transcription from RNA polymerase II promoter	A negative regulation of transcription from RNA polymerase II promoter that results in regulation of reactive oxygen species metabolic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of reactive oxygen species metabolism by down regulation of global transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolism by down regulation of transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolism by negative regulation of transcription from Pol II promoter|regulation of reactive oxygen species metabolism by negative regulation of global transcription from Pol II promoter|regulation of reactive oxygen species metabolic process by negative regulation of gene-specific transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolic process by down-regulation of transcription from RNA polymerase II promoter|regulation of ROS metabolic process by downregulation of global transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolism by inhibition of transcription from RNA polymerase II promoter|regulation of ROS metabolic process by negative regulation of transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolic process by down regulation of transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolism by down-regulation of global transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolism by negative regulation of transcription from RNA polymerase II promoter|regulation of ROS metabolic process by negative regulation of transcription from Pol II promoter|regulation of reactive oxygen species metabolism by downregulation of global transcription from RNA polymerase II promoter|regulation of ROS metabolic process by negative regulation of transcription from RNA polymerase II promoter, global|regulation of reactive oxygen species metabolic process by inhibition of global transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolism by down-regulation of transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolism by downregulation of transcription from RNA polymerase II promoter|regulation of ROS metabolic process by down regulation of global transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolism by negative regulation of transcription from RNA polymerase II promoter, global|regulation of ROS metabolic process by down-regulation of transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolism by inhibition of global transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolic process by downregulation of global transcription from RNA polymerase II promoter|regulation of ROS metabolic process by down-regulation of global transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolic process by negative regulation of global transcription from Pol II promoter|regulation of reactive oxygen species metabolic process by negative regulation of transcription from RNA polymerase II promoter, global|regulation of ROS metabolic process by inhibition of global transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolic process by negative regulation of transcription from Pol II promoter|regulation of ROS metabolic process by negative regulation of gene-specific transcription from RNA polymerase II promoter|regulation of ROS metabolic process by inhibition of transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolic process by down regulation of global transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolic process by down-regulation of global transcription from RNA polymerase II promoter|regulation of ROS metabolic process by down regulation of transcription from RNA polymerase II promoter|regulation of ROS metabolic process by downregulation of transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolic process by downregulation of transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolism by negative regulation of gene-specific transcription from RNA polymerase II promoter|regulation of reactive oxygen species metabolic process by inhibition of transcription from RNA polymerase II promoter|regulation of ROS metabolic process by negative regulation of global transcription from Pol II promoter							kmv	2015-07-17T18:12:06Z					biological_process											owl:Class	
GO:0033849	biolink:NamedThing	chrysanthemyl diphosphate synthase activity	Catalysis of the reaction: 2 dimethylallyl diphosphate = (R,R)-chrysanthemyl diphosphate + diphosphate.	tmpzr1t_l9r_go_relaxed.owl	CPPase activity|dimethylallyl-diphosphate:dimethylallyl-diphosphate dimethylallyltransferase (chrysanthemyl-diphosphate-forming) activity				EC:2.5.1.67|MetaCyc:2.5.1.67-RXN|RHEA:14009|KEGG_REACTION:R08948									molecular_function											owl:Class	
GO:1905268	biolink:NamedThing	negative regulation of chromatin organization	Any process that stops, prevents or reduces the frequency, rate or extent of chromatin organization.	tmpzr1t_l9r_go_relaxed.owl	down regulation of chromatin organisation|inhibition of chromatin organisation|inhibition of chromatin organization|down-regulation of chromatin organisation|negative regulation of chromatin modification|downregulation of chromatin organization|inhibition of establishment or maintenance of chromatin architecture|down regulation of chromatin organization|down regulation of establishment or maintenance of chromatin architecture|negative regulation of establishment or maintenance of chromatin architecture|negative regulation of chromatin organisation|down-regulation of chromatin organization|downregulation of chromatin organisation|down-regulation of establishment or maintenance of chromatin architecture|downregulation of establishment or maintenance of chromatin architecture							pr	2016-06-15T20:14:47Z			GO:1903309		biological_process											owl:Class	
GO:0120217	biolink:NamedThing	DNA gyrase complex	A bacterial type IIA topoisomerase that is unique in its function of introducing negative supercoils into DNA at the expense of ATP hydrolysis and is also capable of relaxing positive supercoils, an activity shared with topoisomerase IV. Typically, it is composed of two copies each of an A subunit (GyrA) and a B subunit (GyrB).	tmpzr1t_l9r_go_relaxed.owl	topoisomerase II complex							krc	2019-08-20T18:36:35Z					cellular_component											owl:Class	
GO:1902767	biolink:NamedThing	isoprenoid biosynthetic process via mevalonate	The chemical reactions and pathways resulting in the formation of isoprenoid via mevalonate.	tmpzr1t_l9r_go_relaxed.owl	isoprenoid synthesis via mevalonate|isoprenoid formation via mevalonate|isoprenoid anabolism via mevalonate|isoprenoid biosynthesis via mevalonate							tt	2014-03-10T23:45:10Z					biological_process											owl:Class	
GO:1902597	biolink:NamedThing	positive regulation of DNA replication origin binding	Any process that activates or increases the frequency, rate or extent of DNA replication origin binding.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of ARS binding|upregulation of DNA replication origin binding|up regulation of DNA replication origin binding|up-regulation of ARS binding|upregulation of ARS binding|activation of ARS binding|up regulation of ARS binding|up-regulation of DNA replication origin binding|activation of DNA replication origin binding							mah	2013-12-19T16:19:57Z					biological_process											owl:Class	
GO:0050558	biolink:NamedThing	maltose epimerase activity	Catalysis of the reaction: alpha-maltose = beta-maltose.	tmpzr1t_l9r_go_relaxed.owl	maltose 1-epimerase activity				MetaCyc:5.1.3.21-RXN|KEGG_REACTION:R07319|RHEA:21228|EC:5.1.3.21									molecular_function											owl:Class	
GO:0018963	biolink:NamedThing	phthalate metabolic process	The chemical reactions and pathways involving phthalate, the anion of phthalic acid. Phthalic acid diesters are used industrially in the production of a variety of household and consumer goods including plastic polymers, lubricating oils, and carriers for perfumes in cosmetics, while phthalic acid itself is used industrially as a plasticizer. Terephthalate is used in the synthesis of polyethylene terephthalate (polyethene terephthlate, abbreviated PET or PETE), a plastic polymer with many commercial uses.	tmpzr1t_l9r_go_relaxed.owl	phthalate metabolism|phthalic acid metabolism|phthalic acid metabolic process				UM-BBD_pathwayID:pth									biological_process											owl:Class	
GO:0035240	biolink:NamedThing	dopamine binding	Binding to dopamine, a catecholamine neurotransmitter formed by aromatic-L-amino-acid decarboxylase from 3,4-dihydroxy-L-phenylalanine.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0050205	biolink:NamedThing	oxamate carbamoyltransferase activity	Catalysis of the reaction: carbamoyl phosphate + oxamate = oxalurate + phosphate.	tmpzr1t_l9r_go_relaxed.owl	carbamoyl-phosphate:oxamate carbamoyltransferase activity|oxamic transcarbamylase activity				RHEA:22984|EC:2.1.3.5|KEGG_REACTION:R02937|MetaCyc:OXAMATE-CARBAMOYLTRANSFERASE-RXN									molecular_function											owl:Class	
GO:0051722	biolink:NamedThing	protein C-terminal methylesterase activity	Catalysis of the reaction: C-terminal protein amino acid methyl ester + H2O = protein amino acid + methanol.	tmpzr1t_l9r_go_relaxed.owl	protein phosphatase methylesterase activity				Reactome:R-HSA-8856951									molecular_function											owl:Class	
GO:0080046	biolink:NamedThing	quercetin 4'-O-glucosyltransferase activity	Catalysis of the transfer of a glucosyl group from UDP-glucose to the 4'-hydroxy group of a quercetin molecule.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-10788									molecular_function											owl:Class	
GO:0050178	biolink:NamedThing	phenylpyruvate tautomerase activity	Catalysis of the reaction: keto-phenylpyruvate = enol-phenylpyruvate.	tmpzr1t_l9r_go_relaxed.owl	phenylpyruvic keto--enol isomerase activity|phenylpyruvate keto-enol-isomerase activity|phenylpyruvate keto--enol tautomerase activity				MetaCyc:PHENYLPYRUVATE-TAUTOMERASE-RXN|RHEA:17097|EC:5.3.2.1									molecular_function											owl:Class	
GO:0039671	biolink:NamedThing	evasion by virus of host natural killer cell activity	Any process by which a virus avoids the effects mediated by the host organism's natural killer (NK) cells.	tmpzr1t_l9r_go_relaxed.owl	evasion by virus of host NK cell killing|viral immunoevasion of host NK cell|protection by virus against host NK cell cytotoxicity|modulation of host NK-cell activity by virus|evasion by virus of host natural killer cell response|suppression by virus of host natural killer cell function							bf	2013-09-25T11:04:53Z					biological_process											owl:Class	
GO:0034780	biolink:NamedThing	glyphosate dehydrogenase activity	Catalysis of the reaction: glyphosate + OH- = glyoxylate + aminomethylphosphonic acid + H+ + 2 e-.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0073									molecular_function											owl:Class	
GO:0140289	biolink:NamedThing	protein mono-ADP-ribosylation	The transfer, from NAD, of a single (mono) ADP-ribose molecule to protein amino acids.	tmpzr1t_l9r_go_relaxed.owl								pg	2018-11-22T13:52:54Z					biological_process											owl:Class	
GO:0061105	biolink:NamedThing	regulation of stomach neuroendocrine cell differentiation	Any process that modulates the rate, frequency or extent of the differentiation of a neuroendocrine cell in the stomach.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-04-29T12:19:37Z					biological_process											owl:Class	
GO:0005915	biolink:NamedThing	zonula adherens	A cell-cell adherens junction which forms a continuous belt near the apex of epithelial cells.	tmpzr1t_l9r_go_relaxed.owl	belt desmosome|adhesion belt|intermediate junction|zonula adhaerens				NIF_Subcellular:sao1400623473									cellular_component											owl:Class	
GO:1902104	biolink:NamedThing	positive regulation of metaphase/anaphase transition of meiotic cell cycle	Any process that activates or increases the frequency, rate or extent of metaphase/anaphase transition of meiotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of meiotic metaphase/anaphase transition|upregulation of metaphase/anaphase transition of meiotic cell cycle|upregulation of meiotic metaphase/anaphase transition|activation of meiotic metaphase/anaphase transition|up-regulation of metaphase/anaphase transition of meiotic cell cycle|positive regulation of meiotic metaphase/anaphase transition|up regulation of metaphase/anaphase transition of meiotic cell cycle|up regulation of meiotic metaphase/anaphase transition|activation of metaphase/anaphase transition of meiotic cell cycle							jl	2013-05-02T12:45:48Z					biological_process											owl:Class	
GO:0003098	biolink:NamedThing	tubuloglomerular feedback	The process in which blood volume is regulated due to a change in the rate of glomerular filtration. This is accomplished by a feedback mechanism that senses changes in the juxtaglomerular apparatus.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Tubuloglomerular_feedback									biological_process											owl:Class	
GO:0050322	biolink:NamedThing	taurine-2-oxoglutarate transaminase activity	Catalysis of the reaction: taurine + 2-oxoglutarate = sulfoacetaldehyde + L-glutamate.	tmpzr1t_l9r_go_relaxed.owl	taurine:2-oxoglutarate aminotransferase activity|taurine--glutamate transaminase activity|taurine--alpha-ketoglutarate aminotransferase activity|taurine aminotransferase activity|taurine transaminase activity				RHEA:16353|MetaCyc:RXN-2301|EC:2.6.1.55									molecular_function											owl:Class	
GO:0039691	biolink:NamedThing	double stranded viral RNA replication	A viral genome replication process where the template genome is double stranded RNA (dsRNA). Genomic dsRNA is first transcribed into single-stranded (ss) mRNA, which is then replicated to ds-genomic RNA.	tmpzr1t_l9r_go_relaxed.owl					VZ:1936			bf	2013-10-17T15:52:19Z					biological_process											owl:Class	
GO:0047954	biolink:NamedThing	glycerol-2-phosphatase activity	Catalysis of the reaction: glycerol 2-phosphate + H(2)O = glycerol + phosphate.	tmpzr1t_l9r_go_relaxed.owl	2-glycerophosphatase activity|glycerol-2-phosphate phosphohydrolase activity|beta-glycerophosphate phosphatase activity|beta-glycerophosphatase activity				EC:3.1.3.19|RHEA:13105|KEGG_REACTION:R01043|MetaCyc:GLYCEROL-2-PHOSPHATASE-RXN									molecular_function											owl:Class	
GO:0015757	biolink:NamedThing	galactose transmembrane transport	The process in which galactose is transported across a lipid bilayer, from one side of a membrane to the other. D-galactose is widely distributed in combined form in plants, animals and microorganisms as a constituent of oligo- and polysaccharides; it also occurs in galactolipids and as its glucoside in lactose and melibiose.	tmpzr1t_l9r_go_relaxed.owl	galactose transport													biological_process											owl:Class	
GO:1900705	biolink:NamedThing	negative regulation of siderophore biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of siderophore biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of siderochrome biosynthesis|down-regulation of siderochrome biosynthetic process|inhibition of siderochrome biosynthesis|down regulation of siderophore biosynthesis|down regulation of siderophore formation|down regulation of siderophore synthesis|down-regulation of siderophore anabolism|downregulation of siderochrome biosynthetic process|down-regulation of siderophore formation|inhibition of siderophore biosynthetic process|negative regulation of siderophore formation|negative regulation of siderophore biosynthetic process, peptide formation|downregulation of siderophore biosynthetic process, peptide formation|down regulation of siderochrome biosynthetic process|down regulation of siderophore biosynthetic process|downregulation of siderophore biosynthesis|downregulation of siderophore biosynthetic process|downregulation of siderochrome biosynthesis|down-regulation of siderophore biosynthesis|downregulation of siderophore formation|down-regulation of siderophore biosynthetic process, peptide formation|negative regulation of siderophore anabolism|inhibition of siderophore biosynthesis|negative regulation of siderophore biosynthetic process, peptide modification|downregulation of siderophore anabolism|inhibition of siderophore anabolism|inhibition of siderophore biosynthetic process, peptide modification|down regulation of siderophore anabolism|down-regulation of siderophore biosynthetic process|negative regulation of siderophore synthesis|negative regulation of siderochrome biosynthesis|inhibition of siderochrome biosynthetic process|down regulation of siderophore biosynthetic process, peptide formation|down regulation of siderochrome biosynthesis|downregulation of siderophore synthesis|negative regulation of siderochrome biosynthetic process|down-regulation of siderophore biosynthetic process, peptide modification|inhibition of siderophore formation|inhibition of siderophore synthesis|downregulation of siderophore biosynthetic process, peptide modification|inhibition of siderophore biosynthetic process, peptide formation|down regulation of siderophore biosynthetic process, peptide modification|down-regulation of siderophore synthesis|negative regulation of siderophore biosynthesis							di	2012-05-22T04:59:49Z					biological_process											owl:Class	
GO:0047663	biolink:NamedThing	aminoglycoside 6'-N-acetyltransferase activity	Catalysis of the reaction: acetyl-CoA + kanamycin B = N(6')-acetylkanamycin B + CoA + H(+). This is acetylation of the 6'-amino group of the 6-deoxy-6-aminoglucose ring.	tmpzr1t_l9r_go_relaxed.owl	AAC(6') activity|aminoglycoside-6-N-acetyltransferase activity|acetyl-CoA:kanamycin-B N6'-acetyltransferase activity|kanamycin 6'-N-acetyltransferase activity|6'-aminoglycoside-N-acetyltransferase activity|aminoglycoside-6'-acetyltransferase activity|aminoglycoside N6'-acetyltransferase activity				MetaCyc:AMINOGLYCOSIDE-N6-ACETYLTRANSFERASE-RXN|KEGG_REACTION:R01889|EC:2.3.1.82|RHEA:16449									molecular_function											owl:Class	
GO:0070071	biolink:NamedThing	proton-transporting two-sector ATPase complex assembly	The aggregation, arrangement and bonding together of a proton-transporting two-sector ATPase complex, a large protein complex that catalyzes the synthesis or hydrolysis of ATP by a rotational mechanism, coupled to the transport of protons across a membrane.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0008841	biolink:NamedThing	dihydrofolate synthase activity	Catalysis of the reaction: ATP + dihydropterate + L-glutamate = ADP + phosphate + dihydrofolate.	tmpzr1t_l9r_go_relaxed.owl	folylpoly-(gamma-glutamate) synthetase-dihydrofolate synthase activity|DHFS activity|7,8-dihydrofolate synthetase activity|H2-folate synthetase activity|dihydropteroate:L-glutamate ligase (ADP-forming) activity|H(2)-folate synthetase activity|FHFS/FPGS activity|7,8-dihydropteroate:L-glutamate ligase (ADP) activity|7,8-dihydropteroate:L-glutamate ligase (ADP-forming)|FHFS activity|dihydrofolate synthetase activity|dihydrofolate synthetase-folylpolyglutamate synthetase activity				RHEA:23584|MetaCyc:DIHYDROFOLATESYNTH-RXN|EC:6.3.2.12									molecular_function											owl:Class	
GO:1990173	biolink:NamedThing	protein localization to nucleoplasm	A process in which a protein is transported to, or maintained in, a location within the nucleoplasm.	tmpzr1t_l9r_go_relaxed.owl	nucleolus to nucleoplasm transport|protein localisation to nucleoplasm	https://github.com/geneontology/go-ontology/issues/14690						mah	2013-08-23T15:01:16Z			GO:0032066		biological_process											owl:Class	
GO:0018522	biolink:NamedThing	benzoyl-CoA reductase activity	Catalysis of the reaction: 2 ADP + cyclohexa-1,5-diene-1-carbonyl-CoA + oxidized ferredoxin + 2 phosphate = 2 ATP + 2 H(2)O + benzoyl-CoA + reduced ferredoxin.	tmpzr1t_l9r_go_relaxed.owl	benzoyl-CoA reductase (dearomatizing) activity|cyclohexa-1,5-diene-1-carbonyl-CoA:ferredoxin oxidoreductase (aromatizing, ATP-forming) activity				RHEA:30199|EC:1.3.7.8|UM-BBD_reactionID:r0190|KEGG_REACTION:R02451|MetaCyc:1.3.99.15-RXN									molecular_function											owl:Class	
GO:0044648	biolink:NamedThing	histone H3-K4 dimethylation	The modification of histone H3 by addition of two methyl groups to lysine at position 4 of the histone.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-07-11T01:27:33Z					biological_process											owl:Class	
GO:0102066	biolink:NamedThing	alpha-patchoulene synthase activityy	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = diphosphoric acid + alpha-patchoulene.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-10603									molecular_function											owl:Class	
GO:0019710	biolink:NamedThing	peptidyl-asparagine methylation	The methylation of peptidyl-asparagine to form peptidyl-N4-methyl-L-asparagine or peptidyl-N4,N4-dimethyl-L-asparagine.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0070|RESID:AA0311							GO:0018018		biological_process											owl:Class	
GO:0016085	biolink:NamedThing	myoinhibitory hormone activity	The action characteristic of myostimulatory hormone, a peptide hormone that inhibits muscle contraction.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0071932	biolink:NamedThing	replication fork reversal	Replication fork processing that involves the unwinding of blocked forks to form four-stranded structures resembling Holliday junctions, which are subsequently resolved.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-09-29T02:34:22Z					biological_process											owl:Class	
GO:0030380	biolink:NamedThing	interleukin-17E receptor binding	Binding to an interleukin-17E receptor.	tmpzr1t_l9r_go_relaxed.owl	interleukin-17E receptor ligand|IL-17E													molecular_function											owl:Class	
GO:0050966	biolink:NamedThing	detection of mechanical stimulus involved in sensory perception of pain	The series of events involved in the perception of pain in which a mechanical stimulus is received and converted into a molecular signal.	tmpzr1t_l9r_go_relaxed.owl	sensory transduction of mechanical stimulus during perception of pain|perception of pain, sensory detection of mechanical stimulus|perception of pain, detection of mechanical stimulus|sensory detection of mechanical stimulus during perception of pain|mechanical nociception|perception of pain, sensory transduction of mechanical stimulus													biological_process											owl:Class	
GO:0002464	biolink:NamedThing	peripheral tolerance induction to nonself antigen	Tolerance induction to nonself antigens in the periphery.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0004065	biolink:NamedThing	arylsulfatase activity	Catalysis of the reaction: a phenol sulfate + H2O = a phenol + sulfate.	tmpzr1t_l9r_go_relaxed.owl	nitrocatechol sulfatase activity|4-methylumbelliferyl sulfatase activity|aryl-sulphate sulphohydrolase activity|aryl-sulfate sulfohydrolase activity|phenolsulfatase activity|sulfatase activity|arylsulphatase activity|estrogen sulfatase activity|arylsulfohydrolase activity|aryl-sulfate sulphohydrolase activity|phenylsulfatase activity|p-nitrophenyl sulfatase activity				RHEA:17261|MetaCyc:ARYLSULFAT-RXN|EC:3.1.6.1									molecular_function											owl:Class	
GO:0034558	biolink:NamedThing	technetium (VII) reductase activity	Catalysis of the reaction: pertechnetate ion + 3/2 H2 = technetium (IV) oxide + H2O + OH-.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0859									molecular_function											owl:Class	
GO:0051646	biolink:NamedThing	mitochondrion localization	Any process in which a mitochondrion or mitochondria are transported to, and/or maintained in, a specific location within the cell.	tmpzr1t_l9r_go_relaxed.owl	mitochondria localization|mitochondrion localisation|localization of mitochondrion|establishment and maintenance of mitochondria localization|establishment and maintenance of mitochondrion localization|mitochondrial localization|localization of mitochondria													biological_process											owl:Class	
GO:1990704	biolink:NamedThing	integral component of Golgi trans cisterna membrane	The component of the Golgi trans membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.	tmpzr1t_l9r_go_relaxed.owl	integral component of trans-Golgi cisterna membrane							bhm	2015-03-16T16:08:07Z					cellular_component											owl:Class	
GO:2000173	biolink:NamedThing	negative regulation of branching morphogenesis of a nerve	Any process that stops, prevents, or reduces the frequency, rate or extent of branching morphogenesis of a nerve.	tmpzr1t_l9r_go_relaxed.owl								rl	2010-10-07T12:07:56Z					biological_process											owl:Class	
GO:0021670	biolink:NamedThing	lateral ventricle development	The process whose specific outcome is the progression of the lateral ventricles over time, from the formation to the mature structure. The two lateral ventricles are a cavity in each of the cerebral hemispheres derived from the cavity of the embryonic neural tube. They are separated from each other by the septum pellucidum, and each communicates with the third ventricle by the foramen of Monro, through which also the choroid plexuses of the lateral ventricles become continuous with that of the third ventricle.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0036082	biolink:NamedThing	extracellular phenylacetaldehyde-gated ion channel activity	Enables the transmembrane transfer of an ion by a channel that opens when extracellular phenylacetaldehyde has been bound by the channel complex or one of its constituent parts.	tmpzr1t_l9r_go_relaxed.owl	ionotropic phenylacetaldehyde receptor activity							bf	2011-12-20T04:49:31Z					molecular_function											owl:Class	
GO:1903944	biolink:NamedThing	negative regulation of hepatocyte apoptotic process	Any process that stops, prevents or reduces the frequency, rate or extent of hepatocyte apoptotic process.	tmpzr1t_l9r_go_relaxed.owl	down regulation of hepatocyte apoptotic process|inhibition of hepatocyte apoptosis|down-regulation of hepatocyte apoptosis|down regulation of hepatocyte apoptosis|downregulation of hepatocyte apoptosis|negative regulation of hepatocyte apoptosis|down-regulation of hepatocyte apoptotic process|downregulation of hepatocyte apoptotic process|inhibition of hepatocyte apoptotic process							sl	2015-02-19T12:54:50Z					biological_process											owl:Class	
GO:0030248	biolink:NamedThing	cellulose binding	Binding to cellulose.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0071817	biolink:NamedThing	MMXD complex	A protein complex that contains the proteins MMS19, MIP18 and XPD, localizes to mitotic spindle during mitosis, and is required for proper chromosome segregation.	tmpzr1t_l9r_go_relaxed.owl	MMS19-MIP18-XPD complex							mah	2010-09-07T10:53:42Z					cellular_component											owl:Class	
GO:0002106	biolink:NamedThing	endonucleolytic cleaveage between SSU-rRNA and LSU-rRNA of tetracistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 4.5S-rRNA, 5S-rRNA)	Endonucleolytic cleavages between the SSU-rRNA and the LSU-rRNA of an rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, Large Subunit (LSU) the 4.5S rRNA, and the 5S rRNA in that order from 5' to 3' along the primary transcript. These cleavages liberate tRNAs from the polycistronic transcript as well as separating the SSU and LSU containing transcript. Note that the use of the word tetracistronic refers only to the number of mature rRNA molecules which will be produced from the primary transcript and ignores tRNAs that may also be present within the primary transcript.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1905591	biolink:NamedThing	regulation of optical nerve axon regeneration	Any process that modulates the frequency, rate or extent of optical nerve axon regeneration.	tmpzr1t_l9r_go_relaxed.owl								pga	2016-10-25T12:58:43Z					biological_process											owl:Class	
GO:0042781	biolink:NamedThing	3'-tRNA processing endoribonuclease activity	Catalysis of the endonucleolytic cleavage of RNA, removing extra 3' nucleotides from tRNA precursor, generating 3' termini of tRNAs. A 3'-hydroxy group is left at the tRNA terminus and a 5'-phosphoryl group is left at the trailer molecule.	tmpzr1t_l9r_go_relaxed.owl	ribonuclease Z activity|RNase Z activity|tRNAse Z|3' tRNase activity|tRNA 3' endonuclease activity|3 tRNase activity|tRNA 3 endonuclease activity|3' tRNA processing endoribonuclease activity	https://github.com/geneontology/go-ontology/issues/21383			MetaCyc:3.1.26.11-RXN|EC:3.1.26.11									molecular_function											owl:Class	
GO:0018766	biolink:NamedThing	dihydrophloroglucinol hydrolase activity	Catalysis of the reaction: dihydrophloroglucinol + OH- = 3-hydroxy-5-oxohexanoate.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0008|KEGG_REACTION:R07831|MetaCyc:R6-RXN									molecular_function											owl:Class	
GO:0032715	biolink:NamedThing	negative regulation of interleukin-6 production	Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-6 production.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of interleukin-6 production|negative regulation of interleukin-6 secretion|down regulation of interleukin-6 production|negative regulation of interleukin-6 biosynthetic process|inhibition of interleukin-6 production|downregulation of interleukin-6 production|negative regulation of IL-6 production											GO:0045409|GO:1900165		biological_process											owl:Class	
GO:0044198	biolink:NamedThing	zf-TRAF domain binding	Binding to a TRAF-type zinc finger domain of a protein.	tmpzr1t_l9r_go_relaxed.owl	zinc-finger-TRAF domain binding|TRAF-type zinc finger domain binding|zinc finger TRAF-type domain binding							jl	2009-10-20T04:09:08Z					molecular_function											owl:Class	
GO:0031391	biolink:NamedThing	Elg1 RFC-like complex	A pentameric replication factor C (RLC) complex, which unloads the DNA polymerase processivity factor proliferating cell nuclear antigen (PCNA) from chromatin and has roles in telomere length regulation and other aspects of genome stability. In Saccharomyces the subunits are known as Elg1p, Rfc2p, Rfc3p, Rfc4p, and Rfc5p.	tmpzr1t_l9r_go_relaxed.owl	Elg1-RLC|RFC (Elg1)|Elg1-RFC													cellular_component											owl:Class	
GO:0071193	biolink:NamedThing	Kv4.2-KChIP2 channel complex	A voltage-gated potassium channel complex that contains the Kv channel interacting protein KChIP2 associated with the channel via interaction with the Kv alpha subunit 4.2.	tmpzr1t_l9r_go_relaxed.owl					CORUM:607			mah	2009-11-23T04:58:09Z					cellular_component											owl:Class	
GO:0050453	biolink:NamedThing	cob(II)alamin reductase activity	Catalysis of the reaction: 2 cob(I)alamin + H(+) + NAD(+) = 2 cob(II)alamin + NADH.	tmpzr1t_l9r_go_relaxed.owl	B12r reductase activity|NADH:cob(II)alamin oxidoreductase activity|vitamin B(12r) reductase activity|vitamin B12 reduction|cob(I)alamin:NAD+ oxidoreductase activity|B(12r) reductase activity|vitamin B12 reductase activity|NADH2:cob(II)alamin oxidoreductase activity|vitamin B12r reductase activity				KEGG_REACTION:R00099|Reactome:R-HSA-3149560|EC:1.16.1.4|MetaCyc:COBIIALAMIN-REDUCTASE-RXN|RHEA:17481									molecular_function											owl:Class	
GO:0022852	biolink:NamedThing	glycine-gated chloride ion channel activity	Enables the transmembrane transfer of a chloride ion by a channel that opens when glycine has been bound by the channel complex or one of its constituent parts.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1900329	biolink:NamedThing	positive regulation of mannotriose transport	Any process that activates or increases the frequency, rate or extent of mannotriose transport.	tmpzr1t_l9r_go_relaxed.owl	upregulation of mannotriose transport|up-regulation of mannotriose transport|up regulation of mannotriose transport|activation of mannotriose transport							tt	2012-04-06T01:50:22Z					biological_process											owl:Class	
GO:0008767	biolink:NamedThing	UDP-galactopyranose mutase activity	Catalysis of the reaction: UDP-D-galactopyranose = UDP-D-galacto-1,4-furanose.	tmpzr1t_l9r_go_relaxed.owl	UDP-D-galactopyranose furanomutase activity|UDPgalactopyranose mutase activity				MetaCyc:GALPMUT-RXN|RHEA:24132|EC:5.4.99.9									molecular_function											owl:Class	
GO:0090371	biolink:NamedThing	regulation of glycerol transport	Any process that modulates the rate, frequency, or extent of the directed movement of glycerol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl								tb	2010-07-12T11:30:22Z					biological_process											owl:Class	
GO:0010348	biolink:NamedThing	lithium:proton antiporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Li+(in) + H+(out) = Li+(out) + H+(in).	tmpzr1t_l9r_go_relaxed.owl	lithium:hydrogen antiporter activity													molecular_function											owl:Class	
GO:0016104	biolink:NamedThing	triterpenoid biosynthetic process	The chemical reactions and pathways resulting in the formation of triterpenoid compounds, terpenoids with six isoprene units.	tmpzr1t_l9r_go_relaxed.owl	triterpenoid formation|triterpene biosynthesis|triterpenoid biosynthesis|triterpenoid anabolism|triterpene biosynthetic process|triterpenoid synthesis													biological_process											owl:Class	
GO:0071092	biolink:NamedThing	alpha3-beta1 integrin-tissue transglutaminase complex	A protein complex that consists of an alpha3-beta1 integrin complex bound to tissue transglutaminase.	tmpzr1t_l9r_go_relaxed.owl	ITGA3-ITGB1-TGM2 complex							mah	2009-11-06T04:47:04Z					cellular_component											owl:Class	
GO:0097671	biolink:NamedThing	SCF-YDR131C ubiquitin ligase complex	An SCF ubiquitin ligase complex in which the F-box protein is YDR131C in S. cerevisiae.	tmpzr1t_l9r_go_relaxed.owl								pr	2014-10-06T10:29:35Z					cellular_component											owl:Class	
GO:1904864	biolink:NamedThing	negative regulation of beta-catenin-TCF complex assembly	Any process that stops, prevents or reduces the frequency, rate or extent of beta-catenin-TCF complex assembly.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of beta-catenin/T-cell factor complex assembly|negative regulation of beta-catenin/LEF complex formation|downregulation of beta-catenin/LEF complex assembly|down regulation of beta-catenin/lymphoid enhancer binding factor complex formation|down regulation of beta-catenin/lymphoid enhancer binding factor complex assembly|down-regulation of beta-catenin/lymphoid enhancer binding factor complex formation|inhibition of beta-catenin/T-cell factor complex assembly|negative regulation of beta-catenin/T-cell factor complex formation|inhibition of beta-catenin-TCF complex assembly|down-regulation of beta-catenin/T-cell factor complex formation|downregulation of beta-catenin/lymphoid enhancer binding factor complex formation|down regulation of beta-catenin-TCF complex assembly|down-regulation of beta-catenin/lymphoid enhancer binding factor complex assembly|down regulation of beta-catenin/LEF complex assembly|down regulation of beta-catenin/LEF complex formation|negative regulation of beta-catenin/lymphoid enhancer binding factor complex assembly|down-regulation of beta-catenin/LEF complex formation|down regulation of beta-catenin/T-cell factor complex assembly|inhibition of beta-catenin/lymphoid enhancer binding factor complex assembly|negative regulation of beta-catenin/T-cell factor complex assembly|inhibition of beta-catenin-TCF complex formation|downregulation of beta-catenin/T-cell factor complex assembly|inhibition of beta-catenin/LEF complex assembly|downregulation of beta-catenin/lymphoid enhancer binding factor complex assembly|inhibition of beta-catenin/lymphoid enhancer binding factor complex formation|downregulation of beta-catenin/T-cell factor complex formation|downregulation of beta-catenin-TCF complex formation|inhibition of beta-catenin/T-cell factor complex formation|down regulation of beta-catenin/T-cell factor complex formation|downregulation of beta-catenin/LEF complex formation|negative regulation of beta-catenin/lymphoid enhancer binding factor complex formation|down-regulation of beta-catenin/LEF complex assembly|negative regulation of beta-catenin-TCF complex formation|negative regulation of beta-catenin/LEF complex assembly|down-regulation of beta-catenin-TCF complex assembly|downregulation of beta-catenin-TCF complex assembly|down regulation of beta-catenin-TCF complex formation|inhibition of beta-catenin/LEF complex formation|down-regulation of beta-catenin-TCF complex formation							bf	2015-12-17T13:50:46Z					biological_process											owl:Class	
GO:0017023	biolink:NamedThing	myosin phosphatase complex	An enzyme complex that catalyzes the removal of the phosphate group from phosphomyosin.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0071372	biolink:NamedThing	cellular response to follicle-stimulating hormone stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a follicle-stimulating hormone stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to FSH stimulus|cellular response to follicle stimulating hormone stimulus							mah	2009-12-11T03:15:56Z					biological_process											owl:Class	
GO:0033933	biolink:NamedThing	branched-dextran exo-1,2-alpha-glucosidase activity	Catalysis of the hydrolysis of (1->2)-alpha-D-glucosidic linkages at the branch points of dextrans and related polysaccharides, producing free D-glucose.	tmpzr1t_l9r_go_relaxed.owl	dextran alpha-1,2 debranching enzyme|1,2-alpha-D-glucosyl-branched-dextran 2-glucohydrolase activity|dextran 1,2-alpha-glucosidase activity				MetaCyc:3.2.1.115-RXN|EC:3.2.1.115									molecular_function											owl:Class	
GO:0097109	biolink:NamedThing	neuroligin family protein binding	Binding to a member of the neuroligin protein family, neuronal cell surface proteins that mediate synapse formation.	tmpzr1t_l9r_go_relaxed.owl								pr	2011-07-28T05:15:22Z					molecular_function											owl:Class	
GO:0044537	biolink:NamedThing	regulation of circulating fibrinogen levels	Any process that modulates the quantity of fibrinogen circulating in the bloodstream.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-03-21T03:15:09Z					biological_process											owl:Class	
GO:0046077	biolink:NamedThing	dUDP metabolic process	The chemical reactions and pathways involving dUDP, deoxyuridine (5'-)diphosphate.	tmpzr1t_l9r_go_relaxed.owl	dUDP metabolism													biological_process											owl:Class	
GO:0061810	biolink:NamedThing	NAD glycohydrolase activity	Catalysis of the reaction: NAD+ + H2O = nicotinamide + ADP-ribose without proceeding through a cyclic ADP-ribose intermediate.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-9637699|EC:3.2.2.5			dph	2016-11-11T13:18:54Z					molecular_function											owl:Class	
GO:1901328	biolink:NamedThing	response to cytochalasin B	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytochalasin B stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2012-08-30T16:36:35Z					biological_process											owl:Class	
GO:0071834	biolink:NamedThing	mating pheromone secretion	The regulated release of a mating pheromone, a peptide hormone that induces a behavioral or physiological response(s) from a responding organism or cell, that contributes to a process of sexual reproduction.	tmpzr1t_l9r_go_relaxed.owl	mating-type pheromone secretion							mah	2010-09-09T11:22:35Z					biological_process											owl:Class	
GO:0039592	biolink:NamedThing	suppression by virus of G2/M transition of host mitotic cell cycle	Any viral process that decreases the rate or extent of progression from G2 phase to M phase of the host mitotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl	host G2/M cell cycle arrest by virus				VZ:876			bf	2012-06-25T02:07:18Z					biological_process											owl:Class	
GO:0120152	biolink:NamedThing	calcium-dependent outer dynein arm binding	Binding to an outer dynein arm in the presence of calcium.	tmpzr1t_l9r_go_relaxed.owl								krc	2018-04-27T16:33:39Z					molecular_function											owl:Class	
GO:1990160	biolink:NamedThing	DnaB-DnaC-Rep-PriC complex	A protein-DNA complex consisting of the helicase loading complex DnaB-DnaC, replication restart proteins Rep and PriC, and associated DNA. Involved in the restart of DNA replication after a stalled replication fork has been repaired.	tmpzr1t_l9r_go_relaxed.owl	DnaB-DnaC-Rep-PriC preprimosome|phi-X174-type preprimosome							bhm	2013-08-02T12:05:25Z					cellular_component											owl:Class	
GO:0098706	biolink:NamedThing	iron ion import across cell outer membrane	The directed movement of iron ions from outside of a cell, across the cell outer membrane and into the periplasmic space.	tmpzr1t_l9r_go_relaxed.owl	ferric iron transmembrane transport|ferric iron import into cell|high affinity ferric iron transport|high-affinity ferric iron transmembrane transport|ferric ion import into cell|ferric iron import across cell outer membrane							pr	2012-12-20T08:33:03Z			GO:0097461|GO:0015683		biological_process											owl:Class	
GO:0035396	biolink:NamedThing	positive regulation of chemokine (C-X-C motif) ligand 9 production	Any process that activates or increases the frequency, rate, or extent of production of chemokine (C-X-C motif) ligand 9.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of MIG production|positive regulation of CXCL9 production							bf	2010-03-23T10:07:17Z					biological_process											owl:Class	
GO:0018138	biolink:NamedThing	peptide cross-linking via L-serine thiazolecarboxylic acid	The chemical reactions and pathways resulting in the formation of a peptidyl cysteine-peptidyl serine cross-link by the condensation of a cysteine thiol with the carbonyl of the preceding residue and alpha-beta dehydrogenation.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0242									biological_process											owl:Class	
GO:0050024	biolink:NamedThing	L-galactonolactone oxidase activity	Catalysis of the reaction: L-galactono-1,4-lactone + O(2) = L-ascorbate + H(2)O(2) + H(+).	tmpzr1t_l9r_go_relaxed.owl	L-galactono-1,4-lactone oxidase activity|L-galactono-1,4-lactone:oxygen 3-oxidoreductase activity|L-xylono-1,4-lactone oxidase activity				EC:1.3.3.12|MetaCyc:1.3.3.12-RXN|RHEA:20617|KEGG_REACTION:R00643							GO:0033733		molecular_function											owl:Class	
GO:0050562	biolink:NamedThing	lysine-tRNA(Pyl) ligase activity	Catalysis of the reaction: tRNA(Pyl) + L-lysine + ATP = L-lysyl-tRNA(Pyl) + diphosphate + AMP.	tmpzr1t_l9r_go_relaxed.owl	L-lysine:tRNAPyl ligase (AMP-forming)|lysine-tRNAPyl ligase activity				MetaCyc:6.1.1.25-RXN									molecular_function											owl:Class	
GO:0044029	biolink:NamedThing	hypomethylation of CpG island	An decrease in the epigenetic methylation of cytosine and adenosine residues in a CpG island in DNA. CpG islands are genomic regions that contain a high frequency of the CG dinucleotide and are often associated with the transcription start site of genes.	tmpzr1t_l9r_go_relaxed.owl	DNA hypomethylation of CpG island													biological_process											owl:Class	
GO:1902567	biolink:NamedThing	negative regulation of eosinophil activation	Any process that stops, prevents or reduces the frequency, rate or extent of eosinophil activation.	tmpzr1t_l9r_go_relaxed.owl	inhibition of eosinophil activation|downregulation of eosinophil activation|down regulation of eosinophil activation|down-regulation of eosinophil activation							ecu	2013-12-10T15:54:43Z					biological_process											owl:Class	
GO:0018353	biolink:NamedThing	protein-phycocyanobilin linkage via S-phycocyanobilin-L-cysteine	The linkage of the chromophore phycocyanobilin to phycocyanin or allophycocyanin via S-phycocyanobilin-L-cysteine.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0131							GO:0018380		biological_process											owl:Class	
GO:0016509	biolink:NamedThing	long-chain-3-hydroxyacyl-CoA dehydrogenase activity	Catalysis of the reaction: (S)-3-hydroxyacyl-CoA + NAD(P)+ = 3-oxoacyl-CoA + NAD(P)H + H+, where the acyl group is a long-chain fatty acid residue. A long-chain fatty acid is a fatty acid with a chain length between C13 and C22.	tmpzr1t_l9r_go_relaxed.owl	LCHAD|long-chain-(S)-3-hydroxyacyl-CoA:NAD+ oxidoreductase activity|beta-hydroxyacyl-CoA dehydrogenase activity|long-chain 3-hydroxyacyl coenzyme A dehydrogenase activity				Reactome:R-HSA-548818|MetaCyc:1.1.1.211-RXN|EC:1.1.1.211	Also see '3-hydroxyacyl-CoA dehydrogenase activity ; GO:0003857'.								molecular_function											owl:Class	
GO:1905237	biolink:NamedThing	response to cyclosporin A	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cyclosporin A stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to cyclophilin							sl	2016-06-07T21:32:06Z					biological_process											owl:Class	
GO:1990048	biolink:NamedThing	anterograde neuronal dense core vesicle transport	The directed movement of substances in neuronal dense core vesicles along axonal microtubules towards the presynapse.	tmpzr1t_l9r_go_relaxed.owl	anterograde dense core granule transport|anterograde dense core granule trafficking													biological_process											owl:Class	
GO:0021709	biolink:NamedThing	cerebellar basket cell differentiation	The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature cerebellar basket cell. Differentiation includes the processes involved in commitment of a neuroblast to a cerebellar basket cell fate. A cerebellar basket cell is an inhibitory GABAergic interneuron found in the cerebellar cortex.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0003940	biolink:NamedThing	L-iduronidase activity	Catalysis of the hydrolysis of alpha-L-iduronosidic linkages in dermatan sulfate.	tmpzr1t_l9r_go_relaxed.owl	alpha-L-iduronidase activity|glycosaminoglycan alpha-L-iduronohydrolase activity				Reactome:R-HSA-9036037|Reactome:R-HSA-1678716|Reactome:R-HSA-2090037|Reactome:R-HSA-1793186|MetaCyc:3.2.1.76-RXN|Reactome:R-HSA-9036041|EC:3.2.1.76|Reactome:R-HSA-2206299									molecular_function											owl:Class	
GO:1990706	biolink:NamedThing	MAD1 complex	A protein complex involved in the assembly of the mitotic checkpoint complex that in turn inhibits the anaphase promoting complex/cyclosome (APC/C).	tmpzr1t_l9r_go_relaxed.owl	MAD1 homodimer							bhm	2015-03-17T15:49:16Z					cellular_component											owl:Class	
GO:0015626	biolink:NamedThing	L-diaminopimelate transmembrane transporter activity	Enables the transfer of L-diaminopimelate from one side of a membrane to the other. L-diaminopimelate is the L-enantiomer anion of 2,6-diaminoheptanedioic acid.	tmpzr1t_l9r_go_relaxed.owl	L-diaminopimelate transporter activity|cystine/diaminopimelate porter activity													molecular_function											owl:Class	
GO:0090603	biolink:NamedThing	sieve element differentiation	The process whereby a relatively unspecialized cell acquires specialized features of a sieve element.	tmpzr1t_l9r_go_relaxed.owl								tb	2014-09-05T16:38:20Z					biological_process											owl:Class	
GO:0030339	biolink:NamedThing	fatty-acyl-ethyl-ester synthase activity	Catalysis of the reaction: a long-chain-acyl ethyl ester + H2O = a long-chain carboxylic acid + ethanol.	tmpzr1t_l9r_go_relaxed.owl	FAEES activity|fatty-acyl ethyl ester synthase|FAEE synthase activity|long-chain-fatty-acyl-ethyl-ester acylhydrolase activity				MetaCyc:FATTY-ACYL-ETHYL-ESTER-SYNTHASE-RXN|EC:3.1.1.67|RHEA:16641									molecular_function											owl:Class	
GO:0034332	biolink:NamedThing	adherens junction organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an adherens junction. An adherens junction is a cell-cell junction composed of the epithelial cadherin-catenin complex at which the cytoplasmic face of the plasma membrane is attached to actin filaments.	tmpzr1t_l9r_go_relaxed.owl	adherens junction organisation													biological_process											owl:Class	
GO:1904619	biolink:NamedThing	response to dimethyl sulfoxide	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dimethyl sulfoxide stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to DMSO							sl	2015-08-27T19:13:49Z					biological_process											owl:Class	
GO:0071586	biolink:NamedThing	CAAX-box protein processing	The second process in a series of specific posttranslational modifications to the CAAX box region of CAAX box proteins, in which the last three amino acids of the protein (AAX) are removed by proteolysis.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-01-28T04:42:45Z					biological_process											owl:Class	
GO:0102237	biolink:NamedThing	ATP:farnesol kinase activity	Catalysis of the reaction: 2-trans,-6-trans-farnesol + ATP = 2-trans,-6-trans-farnesyl monophosphate + ADP + H+.	tmpzr1t_l9r_go_relaxed.owl	ATP-dependent farnesol kinase activity	https://github.com/geneontology/go-ontology/issues/21619			RHEA:61656|MetaCyc:RXN-12304									molecular_function											owl:Class	
GO:0047456	biolink:NamedThing	2-methylisocitrate dehydratase activity	Catalysis of the reaction: (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate = cis-2-methylaconitate + H(2)O.	tmpzr1t_l9r_go_relaxed.owl	(2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate hydro-lyase [(Z)-but-2-ene-1,2,3-tricarboxylate-forming]|(2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate hydro-lyase activity				RHEA:17941|KEGG_REACTION:R04425|MetaCyc:4.2.1.99-RXN|EC:4.2.1.99									molecular_function											owl:Class	
GO:0035081	biolink:NamedThing	induction of programmed cell death by hormones	Any process induced by hormones that directly activates any of the steps required for programmed cell death.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0012502	biolink:NamedThing	induction of programmed cell death	A process which directly activates any of the steps required for programmed cell death.	tmpzr1t_l9r_go_relaxed.owl	induction of nonapoptotic programmed cell death|induction of non-apoptotic programmed cell death											GO:0012503		biological_process											owl:Class	
GO:0070029	biolink:NamedThing	alphav-beta3 integrin-osteopontin complex	A protein complex that consists of an alphav-beta3 integrin complex bound to osteopontin.	tmpzr1t_l9r_go_relaxed.owl	ITGAV-ITGB3-SPP1 complex													cellular_component											owl:Class	
GO:0018577	biolink:NamedThing	catechol 2,3-dioxygenase activity	Catalysis of the reaction: catechol + O2 = 2-hydroxymuconate semialdehyde.	tmpzr1t_l9r_go_relaxed.owl	metapyrocatechase activity|2,3-pyrocatechase activity|catechol 2,3-oxygenase|cato2ase activity|catechol:oxygen 2,3-oxidoreductase (decyclizing)|catechol oxygenase|pyrocatechol 2,3-dioxygenase				UM-BBD_enzymeID:e0156|EC:1.13.11.2|MetaCyc:CATECHOL-23-DIOXYGENASE-RXN|RHEA:17337									molecular_function											owl:Class	
GO:0019102	biolink:NamedThing	male somatic sex determination	The determination of sex and sexual phenotypes in a male organism's soma.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0071257	biolink:NamedThing	cellular response to electrical stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electrical stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to electricity							mah	2009-12-04T03:27:03Z					biological_process											owl:Class	
GO:0009336	biolink:NamedThing	sulfate adenylyltransferase complex (ATP)	An enzyme complex that catalyzes the formation adenylylsulfate from sulfate and ATP.	tmpzr1t_l9r_go_relaxed.owl	sulphate adenylyltransferase complex (ATP)													cellular_component											owl:Class	
GO:0034202	biolink:NamedThing	glycolipid floppase activity	Catalysis of the movement of a glycolipid from the cytosolic to the exoplasmic leaftlet of a membrane, using energy from the hydrolysis of ATP.	tmpzr1t_l9r_go_relaxed.owl	ATPase-coupled intramembrane glycolipid transporter activity|ATP-dependent intramembrane glycolipid transporter activity|glycolipid floppase activity (cytosolic to exoplasmic leaftlet)|glycolipid-translocating activity				Reactome:R-HSA-4570573|Reactome:R-HSA-446212									molecular_function											owl:Class	
GO:0032709	biolink:NamedThing	negative regulation of interleukin-25 production	Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-25 production.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of interleukin-25 production|downregulation of interleukin-25 production|negative regulation of interleukin-25 biosynthetic process|down regulation of interleukin-25 production|negative regulation of IL-25 production|negative regulation of interleukin-25 secretion|inhibition of interleukin-25 production											GO:0045533|GO:0150149		biological_process											owl:Class	
GO:1904093	biolink:NamedThing	negative regulation of autophagic cell death	Any process that stops, prevents or reduces the frequency, rate or extent of autophagic cell death.	tmpzr1t_l9r_go_relaxed.owl	inhibition of autophagic cell death|down-regulation of autophagic cell death|negative regulation of programmed cell death by macroautophagy|inhibition of type II programmed cell death|downregulation of autophagic cell death|inhibition of programmed cell death by macroautophagy|negative regulation of type II programmed cell death|down regulation of autophagic cell death|downregulation of type II programmed cell death|down regulation of programmed cell death by macroautophagy|down-regulation of type II programmed cell death|down regulation of type II programmed cell death|downregulation of programmed cell death by macroautophagy|down-regulation of programmed cell death by macroautophagy							bhm	2015-03-26T16:41:39Z					biological_process											owl:Class	
GO:0071563	biolink:NamedThing	Myo2p-Vac17p-Vac8p transport complex	A protein complex that is involved in transport of vacuoles to a newly formed daughter cell. In yeast, this complex is composed of Myo2p, Vac17p, and Vac8p.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-01-20T03:03:24Z					cellular_component											owl:Class	
GO:0060204	biolink:NamedThing	clathrin-sculpted glutamate transport vesicle lumen	The volume enclosed by the membrane of the clathrin-sculpted glutamate transport vesicle.	tmpzr1t_l9r_go_relaxed.owl	clathrin sculpted glutamate constitutive secretory pathway transport vesicle lumen|clathrin sculpted glutamate transport vesicle lumen													cellular_component											owl:Class	
GO:0032659	biolink:NamedThing	regulation of interleukin-16 production	Any process that modulates the frequency, rate, or extent of interleukin-16 production.	tmpzr1t_l9r_go_relaxed.owl	regulation of interleukin-16 biosynthetic process|regulation of IL-16 production											GO:0045375		biological_process											owl:Class	
GO:0002541	biolink:NamedThing	activation of plasma proteins involved in acute inflammatory response	Any process activating plasma proteins by proteolysis as part of an acute inflammatory response.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0007210	biolink:NamedThing	serotonin receptor signaling pathway	The series of molecular signals generated as a consequence of a serotonin receptor binding to one of its physiological ligands.	tmpzr1t_l9r_go_relaxed.owl	serotonin receptor signalling pathway													biological_process											owl:Class	
GO:1903351	biolink:NamedThing	cellular response to dopamine	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dopamine stimulus.	tmpzr1t_l9r_go_relaxed.owl								mr	2014-08-19T19:33:35Z					biological_process											owl:Class	
GO:0008897	biolink:NamedThing	holo-[acyl-carrier-protein] synthase activity	Catalysis of the reaction: CoA + substrate-serine = adenosine 3',5'-bisphosphate + substrate-serine-4'-phosphopantetheine. The transfer of the 4'-phosphopantetheine (Ppant) co-factor from coenzyme A to the hydroxyl side chain of the serine residue of acyl- or peptidyl-carrier protein (ACP or PCP) to convert them from the apo to the holo form.	tmpzr1t_l9r_go_relaxed.owl	alpha-aminoadipate reductase phosphopantetheinyl transferase activity|PPTase activity|alpha-aminoadipic semialdehyde dehydrogenase-phosphopantetheinyl transferase activity|phosphopantetheinyl transferase|CoA:apo-acyl-carrier-protein pantetheinephosphotransferase activity|acyl carrier protein synthetase activity|acyl carrier protein holoprotein (holo-ACP) synthetase activity|ACPS activity|holo-ACP synthetase activity|phosphopantetheinyltransferase activity|acyl carrier protein synthase activity|CoA-[4'-phosphopantetheine]:apo-acyl-carrier-protein 4'-pantetheinephosphotransferase activity|holosynthase activity|L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase activity|coenzyme A:fatty acid synthetase apoenzyme 4'-phosphopantetheine transferase activity|holo-ACP synthase activity|4'-phosphopantetheinyltransferase activity|holo-[peptidyl-carrier protein] synthase activity|4'-phosphopantetheinyl transferase activity|alphaaminoadipic semialdehyde dehydrogenase-phosphopantetheinyl transferase activity|AcpS|holo-acyl-carrier-protein synthase activity|P-pant transferase activity	https://github.com/geneontology/go-ontology/issues/18113			Reactome:R-HSA-199202|RHEA:12068|EC:2.7.8.7|MetaCyc:HOLO-ACP-SYNTH-RXN							GO:0008958		molecular_function											owl:Class	
GO:0018215	biolink:NamedThing	protein phosphopantetheinylation	The modification of a protein amino acid by phosphopantetheinylation.	tmpzr1t_l9r_go_relaxed.owl	protein amino acid phosphopantetheinylation													biological_process											owl:Class	
GO:0042788	biolink:NamedThing	polysomal ribosome	A ribosome bound to mRNA that forms part of a polysome.	tmpzr1t_l9r_go_relaxed.owl	active ribosome													cellular_component											owl:Class	
GO:0005844	biolink:NamedThing	polysome	A multiribosomal structure representing a linear array of ribosomes held together by messenger RNA. They represent the active complexes in cellular protein synthesis and are able to incorporate amino acids into polypeptides both in vivo and in vitro.	tmpzr1t_l9r_go_relaxed.owl	polyribosome				NIF_Subcellular:sao1038025871|Wikipedia:Polysome									cellular_component											owl:Class	
GO:0033334	biolink:NamedThing	fin morphogenesis	The process in which the anatomical structures of a fin are generated and organized.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0099078	biolink:NamedThing	BORC complex	A protein complex that is involved in positioning of the lysosome within the cytoplasm and which is composed of BLOC1S1, BLOC1S2, BORCS5, BORCS6, BORCS7, BORCS8, KXD1 and SNAPIN. The BORC complex recruits ARL8 at the cytosolic face of lysosomes and couples them to microtubule plus-end-directed kinesin motors.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0030018	biolink:NamedThing	Z disc	Platelike region of a muscle sarcomere to which the plus ends of actin filaments are attached.	tmpzr1t_l9r_go_relaxed.owl	Z band|Z disk|Z line													cellular_component											owl:Class	
GO:0006367	biolink:NamedThing	transcription initiation from RNA polymerase II promoter	Any process involved in the assembly of the RNA polymerase II preinitiation complex (PIC) at an RNA polymerase II promoter region of a DNA template, resulting in the subsequent synthesis of RNA from that promoter. The initiation phase includes PIC assembly and the formation of the first few bonds in the RNA chain, including abortive initiation, which occurs when the first few nucleotides are repeatedly synthesized and then released. Promoter clearance, or release, is the transition between the initiation and elongation phases of transcription.	tmpzr1t_l9r_go_relaxed.owl	transcription initiation from Pol II promoter					Note that promoter clearance is represented as a separate step, not part_of either initiation or elongation.								biological_process											owl:Class	
GO:0090346	biolink:NamedThing	cellular organofluorine metabolic process	The chemical reactions and pathways involving organofluorine compounds, as carried out by individual cells.	tmpzr1t_l9r_go_relaxed.owl								tb	2010-06-02T10:36:42Z					biological_process											owl:Class	
GO:0034423	biolink:NamedThing	autophagosome lumen	The volume enclosed within the autophagosome double-membrane.	tmpzr1t_l9r_go_relaxed.owl	autophagic vacuole lumen					Note that this term should be used for annotating gene products with caution: it should be used only to annotate gene products demonstrated to reside and function normally in the autophagic vacuole lumen, not for molecules that are temporarily found in the lumen prior to degradation.								cellular_component											owl:Class	
GO:2001074	biolink:NamedThing	regulation of metanephric ureteric bud development	Any process that modulates the frequency, rate or extent of metanephric ureteric bud development.	tmpzr1t_l9r_go_relaxed.owl								yaf	2011-09-14T01:11:06Z					biological_process											owl:Class	
GO:0048744	biolink:NamedThing	negative regulation of skeletal muscle fiber development	Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle fiber development. Muscle fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of skeletal muscle fibre development|negative regulation of skeletal myofiber development|downregulation of skeletal muscle fiber development|negative regulation of skeletal myofibre development|down-regulation of skeletal muscle fiber development|down regulation of skeletal muscle fiber development|inhibition of skeletal muscle fiber development													biological_process											owl:Class	
GO:1902358	biolink:NamedThing	sulfate transmembrane transport	The directed movement of sulfate across a membrane.	tmpzr1t_l9r_go_relaxed.owl								dph	2013-08-14T14:46:04Z					biological_process											owl:Class	
GO:0003379	biolink:NamedThing	establishment of cell polarity involved in gastrulation cell migration	The specification and formation of anisotropic intracellular organization that contributes to the self-propelled directed movement of an ameboid cell taking part in gastrulation.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-12-09T06:54:44Z					biological_process											owl:Class	
GO:0003003	biolink:NamedThing	follicular fluid formation in ovarian follicle antrum involved in fused antrum stage	The ovulation cycle process in which one central cavity separating the oocyte/cumulus complex from mural granulosa and theca cells is formed as part of the fused antrum stage of oogenesis.	tmpzr1t_l9r_go_relaxed.owl	follicular fluid formation in ovarian follicle antrum during fused antrum stage													biological_process											owl:Class	
GO:0035708	biolink:NamedThing	interleukin-4-dependent isotype switching to IgE isotypes	The switching of activated B cells from IgM biosynthesis to IgE biosynthesis, accomplished through a recombination process involving an intrachromosomal deletion between switch regions that reside 5' of the IgM and IgE constant region gene segments in the immunoglobulin heavy chain locus, that is dependent on the activity of interleukin 4 (IL-4).	tmpzr1t_l9r_go_relaxed.owl	IL-4-dependent isotype switching to IgE isotypes							bf	2011-03-02T02:40:35Z					biological_process											owl:Class	
GO:0009780	biolink:NamedThing	photosynthetic NADP+ reduction	An NADPH regeneration process that contributes to the light reactions of photosynthesis. The light reactions of photosynthesis use energy from photons to generate high-energy electrons. These electrons are used directly to reduce NADP+ to NADPH. NADPH is a relatively stable molecule and can pass on its hydrogen atom to other molecules in chemical reactions.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0010620	biolink:NamedThing	negative regulation of transcription by transcription factor catabolism	Any process that stops, prevents, or reduces the frequency, rate or extent of DNA-dependent transcription using a mechanism that involves the catabolism of a sequence-specific DNA-binding transcription factor by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1902946	biolink:NamedThing	protein localization to early endosome	A process in which a protein is transported to, or maintained in, a location within an early endosome.	tmpzr1t_l9r_go_relaxed.owl	protein localization in early endosome|protein localisation in early endosome|protein localisation to early endosome							sjp	2014-05-02T08:26:00Z					biological_process											owl:Class	
GO:0005085	biolink:NamedThing	guanyl-nucleotide exchange factor activity	Stimulates the exchange of GDP to GTP on a signaling GTPase, changing its conformation to its active form. Guanine nucleotide exchange factors (GEFs) act by stimulating the release of guanosine diphosphate (GDP) to allow binding of guanosine triphosphate (GTP), which is more abundant in the cell under normal cellular physiological conditions.	tmpzr1t_l9r_go_relaxed.owl	Rho guanyl-nucleotide exchange factor activity|GNRP|GDS|Rho guanine nucleotide exchange factor|cAMP-dependent guanyl-nucleotide exchange factor activity|guanyl-nucleotide releasing factor|GEF|Ral guanyl-nucleotide exchange factor activity|Sar guanyl-nucleotide exchange factor activity|RhoGEF|Rap guanyl-nucleotide exchange factor activity|Rac guanyl-nucleotide exchange factor activity|GDP-dissociation stimulator activity|guanyl-nucleotide release factor activity|ARF guanyl-nucleotide exchange factor activity|Rab guanyl-nucleotide exchange factor activity|Ran guanyl-nucleotide exchange factor activity|Ras guanyl-nucleotide exchange factor activity	https://github.com/geneontology/go-ontology/issues/18749|https://github.com/geneontology/go-ontology/issues/18750			Reactome:R-HSA-416588|Reactome:R-HSA-5617816|Reactome:R-HSA-8877475|Reactome:R-HSA-9695853|Reactome:R-HSA-5655277|Reactome:R-HSA-8877760|Reactome:R-HSA-5623521|Reactome:R-HSA-825631|Reactome:R-HSA-3928633|Reactome:R-HSA-9619803|Reactome:R-HSA-1225951|Reactome:R-HSA-194518|Reactome:R-HSA-1250498|Reactome:R-HSA-5655241|Reactome:R-HSA-442314|Reactome:R-HSA-177945|Reactome:R-HSA-392054|Reactome:R-HSA-8851899|Reactome:R-HSA-205039|Reactome:R-HSA-8876190|Reactome:R-HSA-418850|Reactome:R-HSA-416530|Reactome:R-HSA-8876193|Reactome:R-HSA-5686318|Reactome:R-HSA-8964604|Reactome:R-HSA-8875568|Reactome:R-HSA-9640167|Reactome:R-HSA-5672965|Reactome:R-HSA-8850041|Reactome:R-HSA-9672170|Reactome:R-HSA-171026|Reactome:R-HSA-9026891|Reactome:R-HSA-389348|Reactome:R-HSA-194913|Reactome:R-HSA-8877998|Reactome:R-HSA-8876454|Reactome:R-HSA-5694409|Reactome:R-HSA-8851827|Reactome:R-HSA-420883|Reactome:R-HSA-2029445|Reactome:R-HSA-3965444|Reactome:R-HSA-8876188|Reactome:R-HSA-186834|Reactome:R-HSA-2730840|Reactome:R-HSA-9665408|Reactome:R-HSA-109817|Reactome:R-HSA-419166|Reactome:R-HSA-1250383|Reactome:R-HSA-210977|Reactome:R-HSA-9665009|Reactome:R-HSA-3928651|Reactome:R-HSA-9639286|Reactome:R-HSA-8877612|Reactome:R-HSA-749453|Reactome:R-HSA-379048|Reactome:R-HSA-8876837|Reactome:R-HSA-8877311|Reactome:R-HSA-3928592|Reactome:R-HSA-5218850|Reactome:R-HSA-5654600|Reactome:R-HSA-169904|Reactome:R-HSA-8875591|Reactome:R-HSA-5218839|Reactome:R-HSA-9624845|Reactome:R-HSA-9032067|Reactome:R-HSA-5218829|Reactome:R-HSA-8876615|Reactome:R-HSA-2485180|Reactome:R-HSA-5654647|Reactome:R-HSA-5637806|Reactome:R-HSA-379044|Reactome:R-HSA-8875320|Reactome:R-HSA-6811418|Reactome:R-HSA-9033292|Reactome:R-HSA-3928642|Reactome:R-HSA-5655347|Reactome:R-HSA-354173|Reactome:R-HSA-9666428|Reactome:R-HSA-8853307|Reactome:R-HSA-5654392|Reactome:R-HSA-9607304|Reactome:R-HSA-5654402|Reactome:R-HSA-8848618|Reactome:R-HSA-109807|Reactome:R-HSA-9664991|Reactome:R-HSA-428750|Reactome:R-HSA-8877308|Reactome:R-HSA-1225957|Reactome:R-HSA-445064|Reactome:R-HSA-6807868|Reactome:R-HSA-3928632|Reactome:R-HSA-4093336|Reactome:R-HSA-1433415|Reactome:R-HSA-2179407|Reactome:R-HSA-1433471|Reactome:R-HSA-6811429|Reactome:R-HSA-8875318|Reactome:R-HSA-2029467|Reactome:R-HSA-170979|Reactome:R-HSA-2424477|Reactome:R-HSA-3928628|Reactome:R-HSA-8876191|Reactome:R-HSA-5637808|Reactome:R-HSA-9660824|Reactome:R-HSA-177938|Reactome:R-HSA-1250463|Reactome:R-HSA-5655326|Reactome:R-HSA-6811414|Reactome:R-HSA-8982637|Reactome:R-HSA-939265|Reactome:R-HSA-2424476|Reactome:R-HSA-8877451|Reactome:R-HSA-428917|Reactome:R-HSA-5654618|Reactome:R-HSA-418579|Reactome:R-HSA-5686071|Reactome:R-HSA-180687|Reactome:R-HSA-418856|Reactome:R-HSA-8876616|Reactome:R-HSA-9666430|Reactome:R-HSA-187746|Reactome:R-HSA-156913|Reactome:R-HSA-399938|Reactome:R-HSA-3928612|Reactome:R-HSA-8982640|Reactome:R-HSA-5654413|Reactome:R-HSA-2029451|Reactome:R-HSA-5654663|Reactome:R-HSA-442273|Reactome:R-HSA-442291|Reactome:R-HSA-9665404|Reactome:R-HSA-9672163|Reactome:R-HSA-9634418|Reactome:R-HSA-8877813|Reactome:R-HSA-9665707|Reactome:R-HSA-1168636|Reactome:R-HSA-751029|Reactome:R-HSA-9670436|Reactome:R-HSA-392195|Reactome:R-HSA-399995|Reactome:R-HSA-428535|Reactome:R-HSA-9029158|Reactome:R-HSA-114544|Reactome:R-HSA-380073|Reactome:R-HSA-350769|Reactome:R-HSA-5654426|Reactome:R-HSA-9703441|Reactome:R-HSA-5623508|Reactome:R-HSA-8851877|Reactome:R-HSA-9032798|Reactome:R-HSA-203977|Reactome:R-HSA-442732|Reactome:R-HSA-1306972|Reactome:R-HSA-9665700|Reactome:R-HSA-389350|Reactome:R-HSA-392870							GO:0017112|GO:0005089|GO:0030676|GO:0017034|GO:0005088|GO:0008321|GO:0016220|GO:0019839|GO:0016219|GO:0005086|GO:0008433|GO:0017132|GO:0005087|GO:0005090		molecular_function											owl:Class	
GO:0010072	biolink:NamedThing	primary shoot apical meristem specification	The specification of the meristem which will give rise to all post-embryonic above-ground structures of the plant as well as the non-root below-ground structures, such as rhizomes and tubers.	tmpzr1t_l9r_go_relaxed.owl	embryo shoot apical meristem specification													biological_process											owl:Class	
GO:0009320	biolink:NamedThing	phosphoribosylaminoimidazole carboxylase complex	A protein complex that possesses phosphoribosylaminoimidazole carboxylase activity.	tmpzr1t_l9r_go_relaxed.owl						See also the molecular function term 'phosphoribosylaminoimidazole carboxylase activity ; GO:0004638'.								cellular_component											owl:Class	
GO:0072198	biolink:NamedThing	mesenchymal cell proliferation involved in ureter development	The multiplication or reproduction of cells, resulting in the expansion of a mesenchymal cell population of the ureter, that contributes to ureter development.	tmpzr1t_l9r_go_relaxed.owl	ureteral mesenchymal cell proliferation|ureter mesenchymal cell proliferation							mah	2010-03-01T03:24:41Z					biological_process											owl:Class	
GO:0005814	biolink:NamedThing	centriole	A cellular organelle, found close to the nucleus in many eukaryotic cells, consisting of a small cylinder with microtubular walls, 300-500 nm long and 150-250 nm in diameter. It contains nine short, parallel, peripheral microtubular fibrils, each fibril consisting of one complete microtubule fused to two incomplete microtubules. Cells usually have two centrioles, lying at right angles to each other. At division, each pair of centrioles generates another pair and the twin pairs form the pole of the mitotic spindle.	tmpzr1t_l9r_go_relaxed.owl	daughter centriole|mother centriole				NIF_Subcellular:sao95019936|Wikipedia:Centriole	In most eukaryotic cells, 'ciliary basal body' (GO:0036064) and 'centriole' (GO:0005814) represent a common entity that cycles through its function in cell division, then ciliogenesis, then cell division again. However, these structures are modified extensively as they transition into each other, and may contain different proteins, specific to each component.								cellular_component											owl:Class	
GO:0032608	biolink:NamedThing	interferon-beta production	The appearance of interferon-beta due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	tmpzr1t_l9r_go_relaxed.owl	interferon-beta biosynthetic process|IFN-beta production|IFNB production|interferon-beta secretion					Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.						GO:0035546|GO:0045350		biological_process											owl:Class	
GO:0038157	biolink:NamedThing	granulocyte-macrophage colony-stimulating factor signaling pathway	A series of molecular signals initiated by the binding of the cytokine granulocyte macrophage colony-stimulating factor (GM-CSF) to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. GM-CSF binds to a heterodimer receptor (CSF2R) consisting of an alpha ligand-binding subunit, and a common beta subunit that is shared with other cytokine receptors.	tmpzr1t_l9r_go_relaxed.owl	granulocyte-macrophage colony-stimulating factor signalling pathway|GM-CSF signaling pathway|GM-CSF receptor signaling pathway|CSF2 signaling pathway|granulocyte-macrophage colony-stimulating factor receptor signaling pathway							bf	2012-05-14T01:22:15Z					biological_process											owl:Class	
GO:0038194	biolink:NamedThing	thyroid-stimulating hormone signaling pathway	The series of molecular signals generated as a consequence of thyroid-stimulating hormone (thyrotropin) binding to a cell surface receptor. The pathway proceeds with the receptor transmitting the signal to a heterotrimeric G-protein complex and ends with regulation of a downstream cellular process, e.g. transcription.	tmpzr1t_l9r_go_relaxed.owl	TSH signaling pathway|thyrotropin signaling pathway							bf	2013-10-28T09:03:48Z					biological_process											owl:Class	
GO:0005007	biolink:NamedThing	fibroblast growth factor-activated receptor activity	Combining with a fibroblast growth factor and transmitting the signal across the plasma membrane to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	FGF receptor activity|FGFR|FGF-activated receptor activity|fibroblast growth factor receptor activity					Note that this term represents an activity and not a gene product, and should only be used when the receptor binds the ligand FGF. For receptors that bind other growth factors, consider annotating to terms under 'transmembrane signaling receptor activity ; GO:0004888.								molecular_function											owl:Class	
GO:2000789	biolink:NamedThing	positive regulation of venous endothelial cell fate commitment	Any process that activates or increases the frequency, rate or extent of venous endothelial cell fate commitment.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-06-24T01:26:19Z					biological_process											owl:Class	
GO:0003300	biolink:NamedThing	cardiac muscle hypertrophy	The enlargement or overgrowth of all or part of the heart muscle due to an increase in size of cardiac muscle cells without cell division.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-10-22T10:33:56Z					biological_process											owl:Class	
GO:0002282	biolink:NamedThing	microglial cell activation involved in immune response	The change in morphology and behavior of a microglial cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response.	tmpzr1t_l9r_go_relaxed.owl	microglial cell activation during immune response													biological_process											owl:Class	
GO:0015134	biolink:NamedThing	hexuronate transmembrane transporter activity	Enables the transfer of hexuronates from one side of a membrane to the other. A hexuronate is any monocarboxylic acid derived from a hexose by oxidation of C-6.	tmpzr1t_l9r_go_relaxed.owl	hexuronide transmembrane transporter activity											GO:0015163		molecular_function											owl:Class	
GO:0015736	biolink:NamedThing	hexuronate transmembrane transport	The process in which hexuronate is transported across a lipid bilayer, from one side of a membrane to the other. A hexuronate is any monocarboxylic acid derived from a hexose by oxidation of C-6.	tmpzr1t_l9r_go_relaxed.owl	hexuronate transport													biological_process											owl:Class	
GO:1990745	biolink:NamedThing	EARP complex	A quatrefoil tethering complex required for endocytic recycling.	tmpzr1t_l9r_go_relaxed.owl								sp	2015-05-15T10:23:25Z					cellular_component											owl:Class	
GO:0035146	biolink:NamedThing	tube fusion	The joining of specific branches of a tubular system to form a continuous network.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0000754	biolink:NamedThing	adaptation of signaling pathway by response to pheromone involved in conjugation with cellular fusion	In organisms that undergo conjugation with cellular fusion, the process resulting in desensitization following exposure to pheromone stimulus that act to down-regulate further stimulation or block initial conjugation responses. An example of this is the adaptation to pheromone during conjugation with cellular fusion in Saccharomyces cerevisiae.	tmpzr1t_l9r_go_relaxed.owl	desensitization to pheromone during conjugation with cellular fusion|adaptation to pheromone during conjugation with cellular fusion|adaptation of signalling pathway by response to pheromone involved in conjugation with cellular fusion											GO:0030453|GO:0007331		biological_process											owl:Class	
GO:0014835	biolink:NamedThing	myoblast differentiation involved in skeletal muscle regeneration	The process in which a relatively unspecialized satellite cell acquires specialized features of a myoblast. This occurs as part of skeletal muscle regeneration. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0006409	biolink:NamedThing	tRNA export from nucleus	The directed movement of tRNA from the nucleus to the cytoplasm.	tmpzr1t_l9r_go_relaxed.owl	tRNA transport from nucleus to cytoplasm|tRNA export out of nucleus|tRNA export from cell nucleus|tRNA-nucleus export													biological_process											owl:Class	
GO:0099539	biolink:NamedThing	neuropeptide secretion from presynapse	The secretion of neuropeptides contained within a dense core vesicle by fusion of the granule with the presynaptic membrane, stimulated by a rise in cytosolic calcium ion concentration.	tmpzr1t_l9r_go_relaxed.owl	neuropeptide secretion from presynapse via dense core granule exocytosis													biological_process											owl:Class	
GO:0061535	biolink:NamedThing	glutamate secretion, neurotransmission	The controlled release of glutamate by a cell, in which the glutamate acts as a neurotransmitter.	tmpzr1t_l9r_go_relaxed.owl								dph	2013-06-21T16:14:47Z					biological_process											owl:Class	
GO:2000346	biolink:NamedThing	negative regulation of hepatocyte proliferation	Any process that stops, prevents or reduces the frequency, rate or extent of hepatocyte proliferation.	tmpzr1t_l9r_go_relaxed.owl								mah	2011-02-03T10:27:20Z					biological_process											owl:Class	
GO:0007066	biolink:NamedThing	female meiosis sister chromatid cohesion	The joining of the sister chromatids of a replicated chromosome along the entire length of the chromosome that occurs during meiosis in a female.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1904124	biolink:NamedThing	microglial cell migration	The orderly movement of a microglial cell from one site to another.	tmpzr1t_l9r_go_relaxed.owl								nc	2015-04-10T16:04:49Z					biological_process											owl:Class	
GO:0140222	biolink:NamedThing	pathogen-containing vacuole lumen	The enclosed volume within the sealed membrane of a pathogen-containing vacuole.	tmpzr1t_l9r_go_relaxed.owl	pathogen inclusion lumen|lumen of a pathogen-containing vacuole|pathogen-containing compartment lumen|pathogen-containing vacuolar lumen	https://github.com/geneontology/go-ontology/issues/15580						pg	2018-04-20T06:24:02Z					cellular_component											owl:Class	
GO:0044474	biolink:NamedThing	envenomation resulting in negative regulation of voltage-gated calcium channel activity in other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant stopping, prevention or reduction of the activity of a voltage-gated calcium channel in the bitten organism.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-01-19T02:25:04Z					biological_process											owl:Class	
GO:1901348	biolink:NamedThing	positive regulation of secondary cell wall biogenesis	Any process that activates or increases the frequency, rate or extent of secondary cell wall biogenesis.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of plant-type secondary cell wall biogenesis|positive regulation of cellulose and pectin-containing secondary cell wall biogenesis|positive regulation of secondary cell wall biosynthetic process|positive regulation of secondary cell wall synthesis|upregulation of cellulose and pectin-containing secondary cell wall biogenesis|positive regulation of secondary cell wall anabolism|activation of secondary cell wall biosynthetic process|up-regulation of secondary cell wall formation|up regulation of cellulose and pectin-containing secondary cell wall biogenesis|activation of secondary cell wall formation|upregulation of secondary cell wall biosynthetic process|upregulation of secondary cell wall biogenesis|up-regulation of plant-type secondary cell wall biogenesis|up regulation of secondary cell wall anabolism|up regulation of plant-type secondary cell wall biogenesis|up regulation of secondary cell wall formation|activation of secondary cell wall synthesis|up regulation of secondary cell wall biogenesis|up-regulation of secondary cell wall biosynthetic process|activation of secondary cell wall anabolism|up-regulation of secondary cell wall biogenesis|upregulation of plant-type secondary cell wall biogenesis|up regulation of secondary cell wall biosynthetic process|upregulation of secondary cell wall synthesis|upregulation of secondary cell wall anabolism|up-regulation of secondary cell wall synthesis|upregulation of secondary cell wall formation|up-regulation of secondary cell wall anabolism|up regulation of secondary cell wall synthesis|activation of secondary cell wall biogenesis|positive regulation of secondary cell wall formation|activation of cellulose and pectin-containing secondary cell wall biogenesis|up-regulation of cellulose and pectin-containing secondary cell wall biogenesis|activation of plant-type secondary cell wall biogenesis							tb	2012-09-07T17:59:14Z					biological_process											owl:Class	
GO:0022897	biolink:NamedThing	proton-dependent peptide secondary active transmembrane transporter activity	Enables the transfer of a peptide from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by proton movement.	tmpzr1t_l9r_go_relaxed.owl	hydrogen/oligopeptide symporter													molecular_function											owl:Class	
GO:0000814	biolink:NamedThing	ESCRT II complex	An endosomal sorting complex required for transport and functions downstream of ESCRT I complex. It consists of the class E vacuolar protein sorting (Vps) proteins and is required for the membrane recruitment of ESCRT III complex and binds to ubiquitinated cargoes.	tmpzr1t_l9r_go_relaxed.owl	endosomal sorting complex required for transport													cellular_component											owl:Class	
GO:0038200	biolink:NamedThing	ethylene receptor histidine kinase activity	Combining with ethylene and transmitting the signal within the cell to initiate a change in cell activity by catalysis of the reaction: ATP + a protein-L-histidine = ADP + a protein-L-histidine phosphate.	tmpzr1t_l9r_go_relaxed.owl								bf	2013-12-05T16:25:15Z					molecular_function											owl:Class	
GO:0060434	biolink:NamedThing	bronchus morphogenesis	The process in which the bronchus is generated and organized. The bronchus is the portion of the airway that connects to the lungs.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0021985	biolink:NamedThing	neurohypophysis development	The progression of the neurohypophysis over time from its initial formation until its mature state. The neurohypophysis is the part of the pituitary gland that secretes hormones involved in blood pressure regulation.	tmpzr1t_l9r_go_relaxed.owl	neurophysis development|posterior pituitary development|posterior pituitary gland development													biological_process											owl:Class	
GO:1905685	biolink:NamedThing	negative regulation of plasma membrane repair	Any process that stops, prevents or reduces the frequency, rate or extent of plasma membrane repair.	tmpzr1t_l9r_go_relaxed.owl	down regulation of plasma membrane repair|downregulation of plasma membrane repair|inhibition of plasma membrane repair|down-regulation of plasma membrane repair							bhm	2016-11-14T10:30:38Z					biological_process											owl:Class	
GO:0001778	biolink:NamedThing	plasma membrane repair	The resealing of a cell plasma membrane after cellular wounding due to, for instance, mechanical stress.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0038121	biolink:NamedThing	C-C motif chemokine 21 receptor activity	Combining with the C-C motif chemokine 21 (CCL21) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	CCL21 receptor activity							bf	2012-03-22T01:28:06Z					molecular_function											owl:Class	
GO:0035758	biolink:NamedThing	chemokine (C-C motif) ligand 21 binding	Binding to chemokine (C-C motif) ligand 21.	tmpzr1t_l9r_go_relaxed.owl	CCL21 binding							bf	2011-03-25T02:03:53Z					molecular_function											owl:Class	
GO:0046209	biolink:NamedThing	nitric oxide metabolic process	The chemical reactions and pathways involving nitric oxide, nitrogen monoxide (NO), a colorless gas only slightly soluble in water.	tmpzr1t_l9r_go_relaxed.owl	nitric oxide metabolism													biological_process											owl:Class	
GO:0070657	biolink:NamedThing	neuromast regeneration	The regrowth of a neuromast following its loss or destruction.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-05-28T04:11:44Z					biological_process											owl:Class	
GO:1990596	biolink:NamedThing	histone H3-K4 deacetylation	The modification of histone H3 by the removal of an acetyl group from lysine at position 4 of the histone.	tmpzr1t_l9r_go_relaxed.owl								al	2014-12-23T19:37:15Z					biological_process											owl:Class	
GO:0090361	biolink:NamedThing	regulation of platelet-derived growth factor production	Any process that modulates the rate, frequency, or extent of the appearance of any platelet-derived growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	tmpzr1t_l9r_go_relaxed.owl								tb	2010-07-12T10:32:27Z					biological_process											owl:Class	
GO:0044475	biolink:NamedThing	envenomation resulting in negative regulation of high voltage-gated calcium channel activity in other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant stopping, prevention or reduction of the activity of a high voltage-gated calcium channel in the bitten organism.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-01-19T02:28:11Z					biological_process											owl:Class	
GO:0002525	biolink:NamedThing	acute inflammatory response to non-antigenic stimulus	An acute inflammatory response to non-antigenic stimuli such as heat or physical trauma.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0015120	biolink:NamedThing	phosphoglycerate transmembrane transporter activity	Enables the transfer of phosphoglycerates from one side of a membrane to the other. Phosphoglycerates are important intermediates in glycolysis and 3-phosphoglycerate is a precursor in serine biosynthesis.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0015713	biolink:NamedThing	phosphoglycerate transmembrane transport	The process in which phosphoglycerate is transported across a lipid bilayer, from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	phosphoglycerate transport													biological_process											owl:Class	
GO:0048939	biolink:NamedThing	anterior lateral line nerve glial cell development	The process aimed at the progression of a glial cell in the anterior lateral line nerve over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0140660	biolink:NamedThing	cytoskeletal motor activator activity	Binds to and increases the activity of a motor protein.	tmpzr1t_l9r_go_relaxed.owl	motor activity activator activity	https://github.com/geneontology/go-ontology/issues/21756|https://github.com/geneontology/go-ontology/issues/21627						pg	2021-06-16T11:18:55Z					molecular_function											owl:Class	
GO:0007446	biolink:NamedThing	imaginal disc growth	The increase in mass of imaginal discs by cell proliferation prior to metamorphosis. Imaginal discs are epithelial infoldings in the larvae of holometabolous insects that develop into adult structures (legs, antennae, wings, etc.) during metamorphosis from larval to adult form.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0140676	biolink:NamedThing	oscillatory cAMP signaling	Fluctuation in the extracellular cAMP levels due to the alternate activation of adenylate cyclase, which produces cAMP, and phosphodiesterase, which degrades it. Occurs in Dictyostelium during early sorocarp development. Oscillation in signaling result is directional chemotaxis of cells towards the center of the aggregate.	tmpzr1t_l9r_go_relaxed.owl	cAMP relay	https://github.com/geneontology/go-ontology/issues/21369						pg	2021-06-29T14:14:39Z					biological_process											owl:Class	
GO:0140582	biolink:NamedThing	adenylate cyclase-activating G protein-coupled cAMP receptor signaling pathway	A series of molecular signals initiated by cAMP binding to its receptor on the surface of the target cell, and proceeding with the activated receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex.	tmpzr1t_l9r_go_relaxed.owl	extracellular cAMP signaling pathway	https://github.com/geneontology/go-ontology/issues/20487						pg	2021-01-18T19:30:30Z					biological_process											owl:Class	
GO:0098698	biolink:NamedThing	postsynaptic specialization assembly	The aggregation, arrangement and bonding together of a set of components to form a postsynaptic specialization, a region that lies adjacent to the cytoplasmic face of the postsynaptic membrane.	tmpzr1t_l9r_go_relaxed.owl								dos	2017-04-04T17:22:01Z					biological_process											owl:Class	
GO:0071918	biolink:NamedThing	urea transmembrane transport	The process in which urea, the water-soluble compound H2N-CO-NH2, is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	urea membrane transport					Note that this term is not intended for use in annotating lateral movement within membranes.		mah	2010-09-24T10:41:36Z					biological_process											owl:Class	
GO:0003212	biolink:NamedThing	cardiac left atrium morphogenesis	The process in which the left cardiac atrium is generated and organized.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-10-13T09:48:16Z					biological_process											owl:Class	
GO:0005745	biolink:NamedThing	m-AAA complex	Protease complex of the mitochondrial inner membrane that is involved in mitochondrial protein turnover and in processing of proteins imported into mitochondria.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0098842	biolink:NamedThing	postsynaptic early endosome	An early endosome of the postsynapse. It acts as the major sorting station on the endocytic pathway, targeting neurotransmitter receptors for degregation or recycling.	tmpzr1t_l9r_go_relaxed.owl						Commonly used markers for postsynaptic early endosomes include RAB5A and EEA1.								cellular_component											owl:Class	
GO:0090137	biolink:NamedThing	epithelial cell-cell adhesion involved in epithelium migration	The attachment of an epithelial cell to another epithelial cell via adhesion molecules that contributes to epithelium migration.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-12-08T01:58:19Z					biological_process											owl:Class	
GO:0090132	biolink:NamedThing	epithelium migration	The process in which the population of cells that make up an epithelium undergo directed movement.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-12-07T03:19:34Z					biological_process											owl:Class	
GO:0015640	biolink:NamedThing	peptidoglycan peptide transmembrane transporter activity	Enables the transfer of peptidoglycan peptides from one side of a membrane to the other. Peptidoglycan peptides are the oligopeptides found in peptidoglycan networks which cross-link the polysaccharide chains.	tmpzr1t_l9r_go_relaxed.owl	murein peptide transporter activity|muropeptide transporter activity													molecular_function											owl:Class	
GO:0071637	biolink:NamedThing	regulation of monocyte chemotactic protein-1 production	Any process that modulates the frequency, rate, or extent of production of monocyte chemotactic protein-1.	tmpzr1t_l9r_go_relaxed.owl	regulation of CCL2 production|regulation of MCP-1 production							mah	2010-02-12T10:39:51Z					biological_process											owl:Class	
GO:0003268	biolink:NamedThing	fibroblast growth factor receptor signaling pathway involved in regulation of secondary heart field cardioblast proliferation	The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands contributing to the modulation of the frequency, rate or extent of cardioblast proliferation in the secondary heart field. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.	tmpzr1t_l9r_go_relaxed.owl	fibroblast growth factor receptor signalling pathway involved in regulation of secondary heart field cardioblast cell proliferation|fibroblast growth factor receptor signaling pathway involved in regulation of second heart field cardioblast cell proliferation|fibroblast growth factor receptor signaling pathway involved in regulation of secondary heart field cardioblast cell proliferation							dph	2009-10-15T02:43:03Z					biological_process											owl:Class	
GO:0044490	biolink:NamedThing	positive regulation of voltage-gated sodium channel activity in other organism	Any process that activates or increases the frequency, rate or extent of the activity of a voltage-gated sodium channel in another organism.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-02-01T12:21:26Z					biological_process											owl:Class	
GO:0045121	biolink:NamedThing	membrane raft	Any of the small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes. Small rafts can sometimes be stabilized to form larger platforms through protein-protein and protein-lipid interactions.	tmpzr1t_l9r_go_relaxed.owl	lipid raft|glycolipid-enriched membrane domain|GEM domain				Wikipedia:Lipid_raft									cellular_component											owl:Class	
GO:0046975	biolink:NamedThing	histone methyltransferase activity (H3-K36 specific)	Catalysis of the reaction: S-adenosyl-L-methionine + histone H3 L-lysine (position 36) = S-adenosyl-L-homocysteine + histone H3 N6-methyl-L-lysine (position 36). This reaction is the addition of a methyl group onto lysine at position 36 of the histone H3 protein.	tmpzr1t_l9r_go_relaxed.owl	histone lysine N-methyltransferase activity (H3-K36 specific)|histone methylase activity (H3-K36 specific)													molecular_function											owl:Class	
GO:0021577	biolink:NamedThing	hindbrain structural organization	The process that contributes to the act of creating the structural organization of the hindbrain. This process pertains to the physical shaping of a rudimentary structure. The hindbrain is the region consisting of the medulla, pons and cerebellum. Areas of the hindbrain control motor and autonomic functions.	tmpzr1t_l9r_go_relaxed.owl	hindbrain structural organisation													biological_process											owl:Class	
GO:0048853	biolink:NamedThing	forebrain morphogenesis	The process in which the anatomical structures of the forebrain are generated and organized. The forebrain is the anterior of the three primary divisions of the developing chordate brain or the corresponding part of the adult brain (in vertebrates, includes especially the cerebral hemispheres, the thalamus, and the hypothalamus and especially in higher vertebrates is the main control center for sensory and associative information processing, visceral functions, and voluntary motor functions).	tmpzr1t_l9r_go_relaxed.owl	prosencephalon morphogenesis													biological_process											owl:Class	
GO:0048854	biolink:NamedThing	brain morphogenesis	The process in which the anatomical structures of the brain are generated and organized. The brain is one of the two components of the central nervous system and is the center of thought and emotion. It is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.).	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0035658	biolink:NamedThing	Mon1-Ccz1 complex	A protein complex that functions as a guanine nucleotide exchange factor (GEF) and converts Rab-GDP to Rab-GTP. In S. cerevisiae, this complex consists of at least Mon1 and Ccz1, and serves as a GEF for the Rab Ypt7p.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-01-28T11:31:20Z					cellular_component											owl:Class	
GO:0001184	biolink:NamedThing	promoter clearance from RNA polymerase I promoter for nuclear large rRNA transcript	Any process involved in the transition from the initiation to the elongation phases of transcription by RNA polymerase I at a promoter for the nuclear large ribosomal RNA (rRNA) transcript, generally including a conformational change from the initiation conformation to the elongation conformation. Promoter clearance often involves breaking contact with transcription factors involved only in the initiation phase and making contacts with elongation specific factors.	tmpzr1t_l9r_go_relaxed.owl								krc	2011-08-15T04:03:52Z					biological_process											owl:Class	
GO:0036238	biolink:NamedThing	gallate dioxygenase activity	Catalysis of the reaction: gallate + O2 = (1E)-4-oxobut-1-ene-1,2,4-tricarboxylate.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:GALLATE-DIOXYGENASE-RXN|EC:1.13.11.57|RHEA:28927|KEGG_REACTION:R09565			bf	2012-05-22T01:54:09Z					molecular_function											owl:Class	
GO:0035739	biolink:NamedThing	CD4-positive, alpha-beta T cell proliferation	The expansion of a CD4-positive, alpha-beta T cell population by cell division.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-03-17T02:12:48Z					biological_process											owl:Class	
GO:1900249	biolink:NamedThing	positive regulation of cytoplasmic translational elongation	Any process that activates or increases the frequency, rate or extent of cytoplasmic translational elongation.	tmpzr1t_l9r_go_relaxed.owl	activation of cytoplasmic translational elongation|up-regulation of cytoplasmic translational elongation|upregulation of cytoplasmic translational elongation|up regulation of cytoplasmic translational elongation							vw	2012-04-03T05:07:24Z					biological_process											owl:Class	
GO:0021775	biolink:NamedThing	smoothened signaling pathway involved in ventral spinal cord interneuron specification	The series of molecular signals initiated by binding of a ligand to the transmembrane receptor smoothened in a precursor cell in the ventral spinal cord that contributes to the commitment of the precursor cell to an interneuron fate.	tmpzr1t_l9r_go_relaxed.owl	smoothened signalling pathway involved in ventral spinal cord interneuron specification|hh signaling pathway involved in ventral spinal cord interneuron specification|hedgehog signaling pathway involved in ventral spinal cord interneuron specification													biological_process											owl:Class	
GO:0070183	biolink:NamedThing	mitochondrial tryptophanyl-tRNA aminoacylation	The process of coupling tryptophan to tryptophanyl-tRNA in a mitochondrion, catalyzed by tryptophanyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0061006	biolink:NamedThing	regulation of cell proliferation involved in kidney morphogenesis	Any process that modulates the frequency, rate or extent of cell proliferation that contributes to the shaping of the kidney.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-01-21T11:25:23Z					biological_process											owl:Class	
GO:0034735	biolink:NamedThing	transcription factor TFIIIC2 complex	A transcription factor complex that forms part of the TFIIIC complex, observed in human; composed of five subunits (GTF3C1/hTFIIIC220/TFIIICalpha, GTF3C2/hTFIIIC110/TFIIICbeta, GTF3C3/hTFIIIC102/TFIIICgamma, GTF3C4/hTFIIIC90/TFIIICdelta and GTF3C5/hTFIIIC63/TFIIICepsilon in human) that together recognize the type 2 RNA polymerase III promoter.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:1902690	biolink:NamedThing	positive regulation of NAD metabolic process	Any process that activates or increases the frequency, rate or extent of NAD metabolic process.	tmpzr1t_l9r_go_relaxed.owl	upregulation of oxidized nicotinamide adenine dinucleotide metabolic process|up regulation of NAD metabolic process|activation of NAD (oxidized) metabolism|activation of NAD (oxidized) metabolic process|up-regulation of NAD (oxidized) metabolic process|upregulation of oxidized NAD metabolism|up regulation of oxidized NAD metabolic process|activation of oxidized nicotinamide adenine dinucleotide metabolic process|up-regulation of NAD (oxidized) metabolism|upregulation of nicotinamide adenine dinucleotide metabolic process|up regulation of oxidized NAD metabolism|activation of oxidized NAD metabolic process|up regulation of NAD (oxidized) metabolic process|upregulation of oxidized NAD metabolic process|up-regulation of oxidized NAD metabolism|positive regulation of NAD (oxidized) metabolic process|up-regulation of NAD phosphorylation and dephosphorylation|up-regulation of NAD metabolism|positive regulation of NAD (oxidized) metabolism|up regulation of NAD (oxidized) metabolism|activation of oxidized nicotinamide adenine dinucleotide metabolism|upregulation of oxidized nicotinamide adenine dinucleotide metabolism|up regulation of NAD metabolism|positive regulation of NAD phosphorylation and dephosphorylation|positive regulation of oxidized nicotinamide adenine dinucleotide metabolism|activation of oxidized NAD metabolism|activation of NAD metabolic process|up-regulation of oxidized NAD metabolic process|positive regulation of oxidized NAD metabolism|up regulation of oxidized nicotinamide adenine dinucleotide metabolism|activation of nicotinamide adenine dinucleotide metabolism|upregulation of NAD metabolic process|up-regulation of nicotinamide adenine dinucleotide metabolic process|positive regulation of NAD metabolism|up-regulation of oxidized nicotinamide adenine dinucleotide metabolic process|upregulation of NAD metabolism|up-regulation of nicotinamide adenine dinucleotide metabolism|upregulation of NAD (oxidized) metabolism|activation of NAD phosphorylation and dephosphorylation|up-regulation of NAD metabolic process|activation of nicotinamide adenine dinucleotide metabolic process|up-regulation of oxidized nicotinamide adenine dinucleotide metabolism|positive regulation of oxidized NAD metabolic process|upregulation of NAD (oxidized) metabolic process|positive regulation of nicotinamide adenine dinucleotide metabolism|up regulation of nicotinamide adenine dinucleotide metabolic process|positive regulation of oxidized nicotinamide adenine dinucleotide metabolic process|upregulation of NAD phosphorylation and dephosphorylation|up regulation of NAD phosphorylation and dephosphorylation|upregulation of nicotinamide adenine dinucleotide metabolism|positive regulation of nicotinamide adenine dinucleotide metabolic process|activation of NAD metabolism|up regulation of nicotinamide adenine dinucleotide metabolism|up regulation of oxidized nicotinamide adenine dinucleotide metabolic process							di	2014-02-12T18:59:09Z					biological_process											owl:Class	
GO:0140416	biolink:NamedThing	transcription regulator inhibitor activity	A molecular function regulator that inhibits the activity of a transcription regulator via direct binding and/or post-translational modification.	tmpzr1t_l9r_go_relaxed.owl	DNA-binding transcription factor inhibitor activity	https://github.com/geneontology/go-ontology/issues/18596|https://github.com/geneontology/go-ontology/issues/16132				Usage guidance: transcription regulator inhibitors bind to a transcription regulator to prevent it from reaching the chromatin. This activity does not occur at the promoter. For activities that do occur at the promoter, consider GO:0001217 ; DNA-binding transcription repressor activity or GO:0003714 ; transcription corepressor activity. An example of a transcription regulator is TCF23 Q7RTU1 is an example of a protein that regulates transcription factors by heterodimerising or binding to DbTFs and prevent DNA binding and their specific genomic binding site where the dbTF would have activated or repressed transcription. Also an example is NFKBIA P25963 which has a different way of regulating transcription factor activity by sequestering the dbTF (complex) in the cytoplasm. Another example is the HSP90 and HSP23 proteins that sequester steroid receptors away from the DNA.		pg	2020-01-21T14:17:39Z					molecular_function											owl:Class	
GO:2000496	biolink:NamedThing	negative regulation of cell proliferation involved in compound eye morphogenesis	Any process that stops, prevents or reduces the frequency, rate or extent of cell proliferation involved in compound eye morphogenesis.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-03-18T02:19:22Z					biological_process											owl:Class	
GO:0001836	biolink:NamedThing	release of cytochrome c from mitochondria	The process that results in the movement of cytochrome c from the mitochondrial intermembrane space into the cytosol, which is part of the apoptotic signaling pathway and leads to caspase activation.	tmpzr1t_l9r_go_relaxed.owl						The release of cytochrome c from mitochondria is a central event in the signaling phase of the apoptotic process, and it is often used by researchers to monitor this type of cell death. Any event that induces apoptosis will at some point induce the release of cytochrome c from mitochondria. Therefore, this term should only be used to annotate gene products that are directly involved in this process. An example is Drp1 (DNM1L, UniProt symbol O00429) in PMID:20850011.								biological_process											owl:Class	
GO:0072284	biolink:NamedThing	metanephric S-shaped body morphogenesis	The process in which the metanephric S-shaped body is generated and organized. The metanephric S-shaped body is the successor of the metanephric comma-shaped body that contributes to the morphogenesis of a nephron in the metanephros.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-04-01T03:41:36Z					biological_process											owl:Class	
GO:0000381	biolink:NamedThing	regulation of alternative mRNA splicing, via spliceosome	Any process that modulates the frequency, rate or extent of alternative splicing of nuclear mRNAs.	tmpzr1t_l9r_go_relaxed.owl	regulation of alternative nuclear mRNA splicing, via spliceosome|splice site selection													biological_process											owl:Class	
GO:0080177	biolink:NamedThing	plastoglobule organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the plastoglobule. Plastoglobule is a lipoprotein particle present in chloroplasts. They are rich in non-polar lipids (triglycerides, esters) as well as in prenylquinones, plastoquinone and tocopherols. Plastoglobules are often associated with thylakoid membranes, suggesting an exchange of lipids with thylakoids.	tmpzr1t_l9r_go_relaxed.owl	plastoglobule organisation							dhl	2011-04-28T04:13:07Z					biological_process											owl:Class	
GO:0035878	biolink:NamedThing	nail development	The process whose specific outcome is the progression of a nail over time, from its formation to the mature structure. A nail is a horn-like envelope covering the outer end of a finger or toe, and consists of the nail plate, the nail matrix and the nail bed below it, and the grooves surrounding it.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-05-31T02:30:34Z					biological_process											owl:Class	
GO:0060478	biolink:NamedThing	acrosomal vesicle exocytosis	The calcium ion regulated exocytosis which results in fusion of the acrosomal vesicle with the plasma membrane of the sperm as part of the acrosome reaction.	tmpzr1t_l9r_go_relaxed.owl	acrosomal granule exocytosis|acrosome exocytosis													biological_process											owl:Class	
GO:0031924	biolink:NamedThing	vitamin B6 transmembrane transporter activity	Enables the transfer of any of the vitamin B6 compounds, pyridoxal, pyridoxamine and pyridoxine and the active form, pyridoxal phosphate, from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	vitamin B6 transporter activity													molecular_function											owl:Class	
GO:0001673	biolink:NamedThing	male germ cell nucleus	The nucleus of a male germ cell, a reproductive cell in males.	tmpzr1t_l9r_go_relaxed.owl	male germ-cell nucleus											GO:0043081		cellular_component											owl:Class	
GO:0070892	biolink:NamedThing	lipoteichoic acid immune receptor activity	Combining with lipoteichoic acid and transmitting the signal to initiate an innate immune response.	tmpzr1t_l9r_go_relaxed.owl	lipoteichoic acid receptor activity							mah	2009-09-01T02:59:24Z					molecular_function											owl:Class	
GO:0070891	biolink:NamedThing	lipoteichoic acid binding	Binding to lipoteichoic acid.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-09-01T02:56:36Z					molecular_function											owl:Class	
GO:0002391	biolink:NamedThing	platelet activating factor production involved in inflammatory response	The synthesis or release of platelet activating factor following a stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels.	tmpzr1t_l9r_go_relaxed.owl	platelet activating factor secretion involved in acute inflammatory response|platelet activating factor secretion|platelet activating factor secretion involved in inflammatory response|platelet activating factor production involved in acute inflammatory response|platelet activating factor production	https://github.com/geneontology/go-ontology/issues/20154										GO:0002535|GO:0002392|GO:0002390		biological_process											owl:Class	
GO:0072025	biolink:NamedThing	distal convoluted tubule development	The process whose specific outcome is the progression of the distal convoluted tubule over time, from its formation to the mature structure. The distal convoluted tubule is the first segment of the nephron lying just downstream from the loop of Henle, immediately after the macula densa. Among other functions, in humans it is responsible for the reabsorption of about 5% of filtered sodium via the thiazide-sensitive Na-Cl symporter.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-01-25T02:40:45Z					biological_process											owl:Class	
GO:0150073	biolink:NamedThing	regulation of protein-glutamine gamma-glutamyltransferase activity	Any process that modulates the frequency, rate or extent of protein-glutamine gamma-glutamyltransferase activity.	tmpzr1t_l9r_go_relaxed.owl								bc	2018-07-25T10:03:10Z					biological_process											owl:Class	
GO:0030316	biolink:NamedThing	osteoclast differentiation	The process in which a relatively unspecialized monocyte acquires the specialized features of an osteoclast. An osteoclast is a specialized phagocytic cell associated with the absorption and removal of the mineralized matrix of bone tissue.	tmpzr1t_l9r_go_relaxed.owl	osteoclast cell differentiation													biological_process											owl:Class	
GO:0021804	biolink:NamedThing	negative regulation of cell adhesion in ventricular zone	The process that results in the loss of attachments of a cell in the ventricular zone.	tmpzr1t_l9r_go_relaxed.owl	down regulation of cell adhesion in ventricular zone|down-regulation of cell adhesion in ventricular zone|inhibition of cell adhesion in ventricular zone|downregulation of cell adhesion in ventricular zone													biological_process											owl:Class	
GO:0045178	biolink:NamedThing	basal part of cell	The region of a cell situated near the base. For example, in a polarized epithelial cell, the basal surface rests on the basal lamina that separates the epithelium from other tissue.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:1904503	biolink:NamedThing	negative regulation of lipophagy	Any process that stops, prevents or reduces the frequency, rate or extent of lipophagy.	tmpzr1t_l9r_go_relaxed.owl	down regulation of lipophagy|inhibition of lipophagy|down-regulation of lipophagy|downregulation of lipophagy							dph	2015-07-24T11:37:18Z					biological_process											owl:Class	
GO:0061602	biolink:NamedThing	molybdenum cofactor cytidylyltransferase activity	Catalysis of the reaction CTP + molybdenum cofactor = diphosphate + cytidylyl molybdenum cofactor.	tmpzr1t_l9r_go_relaxed.owl					RHEA:31335|EC:2.7.7.76			dph	2014-02-10T14:46:38Z					molecular_function											owl:Class	
GO:0043312	biolink:NamedThing	neutrophil degranulation	The regulated exocytosis of secretory granules containing preformed mediators such as proteases, lipases, and inflammatory mediators by a neutrophil.	tmpzr1t_l9r_go_relaxed.owl	heterophil degranulation|neutrophil granule exocytosis													biological_process											owl:Class	
GO:1902868	biolink:NamedThing	positive regulation of retina development in camera-type eye	Any process that activates or increases the frequency, rate or extent of retina development in camera-type eye.	tmpzr1t_l9r_go_relaxed.owl	upregulation of retina development in camera-type eye|positive regulation of retinal development|activation of retina development in camera-type eye|up-regulation of retina development in camera-type eye|up regulation of retina development in camera-style eye|activation of retina development in camera-style eye|positive regulation of retina development in camera-style eye|up-regulation of retina development in camera-style eye|upregulation of retinal development|activation of retinal development|upregulation of retina development in camera-style eye|up regulation of retinal development|up regulation of retina development in camera-type eye|up-regulation of retinal development							mr	2014-04-03T15:24:29Z					biological_process											owl:Class	
GO:1990202	biolink:NamedThing	FMN reductase complex	A protein complex capable of FMN reductase activity. Reduces FMN to FMNH2 in a NAD(P)H-dependent manner. In E.coli, consists of a SsuE dimer.	tmpzr1t_l9r_go_relaxed.owl	flavin oxidoreductase complex, NAD(P)H-dependent|FMN reductase complex, NAD(P)H-dependent|SsuE complex|FMN oxidoreductase complex, NAD(P)H-dependent							bhm	2013-10-03T15:07:20Z					cellular_component											owl:Class	
GO:0032282	biolink:NamedThing	plastid acetyl-CoA carboxylase complex	An acetyl-CoA carboxylase complex located in the stroma of a plastid.	tmpzr1t_l9r_go_relaxed.owl	plastid ACCase complex													cellular_component											owl:Class	
GO:0004911	biolink:NamedThing	interleukin-2 receptor activity	Combining with interleukin-2 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	IL-2R|IL-2 receptor activity													molecular_function											owl:Class	
GO:0032454	biolink:NamedThing	histone H3-methyl-lysine-9 demethylase activity	Catalysis of the removal of a methyl group from a modified lysine residue at position 9 of the histone H3 protein.	tmpzr1t_l9r_go_relaxed.owl	H3K49 demethylase activity|histone demethylase activity (H3-K9 specific)	https://github.com/geneontology/go-ontology/issues/21089			Reactome:R-HSA-9011985|Reactome:R-HSA-997263|Reactome:R-HSA-9011949									molecular_function											owl:Class	
GO:1900461	biolink:NamedThing	positive regulation of pseudohyphal growth by positive regulation of transcription from RNA polymerase II promoter	Any process that activates or increases the frequency, rate or extent of pseudohyphal growth by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter.	tmpzr1t_l9r_go_relaxed.owl								dgf	2012-05-01T07:01:40Z					biological_process											owl:Class	
GO:0060358	biolink:NamedThing	negative regulation of leucine import	Any process that decreases the rate, frequency or extent of leucine import. Leucine import is the directed movement of leucine into a cell or organelle.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0090166	biolink:NamedThing	Golgi disassembly	A cellular process that results in the breakdown of a Golgi apparatus that contributes to Golgi inheritance.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-12-08T09:15:11Z					biological_process											owl:Class	
GO:0015210	biolink:NamedThing	uracil transmembrane transporter activity	Enables the transfer of uracil, 2,4-dioxopyrimidine, from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	uracil/uridine permease activity													molecular_function											owl:Class	
GO:0042874	biolink:NamedThing	D-glucuronate transmembrane transport	The process in which D-glucuronate, the D-enantiomer of glucuronate, is transported across a lipid bilayer, from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	D-glucuronate transport													biological_process											owl:Class	
GO:1904436	biolink:NamedThing	negative regulation of transferrin receptor binding	Any process that stops, prevents or reduces the frequency, rate or extent of transferrin receptor binding.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of transferrin receptor binding|downregulation of transferrin receptor binding|down regulation of transferrin receptor binding|inhibition of transferrin receptor binding							kom	2015-07-06T13:49:07Z					biological_process											owl:Class	
GO:0060352	biolink:NamedThing	cell adhesion molecule production	The appearance of a cell adhesion molecule due to biosynthesis or secretion.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0030479	biolink:NamedThing	actin cortical patch	An endocytic patch  that consists of an actin-containing structure found at the plasma membrane in cells; formed of networks of branched actin filaments that lie just beneath the plasma membrane and assemble, move, and disassemble rapidly. An example of this is the actin cortical patch found in Saccharomyces cerevisiae.	tmpzr1t_l9r_go_relaxed.owl	actin patch											GO:0005857		cellular_component											owl:Class	
GO:0050873	biolink:NamedThing	brown fat cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a brown adipocyte, an animal connective tissue cell involved in adaptive thermogenesis. Brown adipocytes contain multiple small droplets of triglycerides and a high number of mitochondria.	tmpzr1t_l9r_go_relaxed.owl	brown adipocyte cell differentiation|brown adipocyte differentiation													biological_process											owl:Class	
GO:0007303	biolink:NamedThing	cytoplasmic transport, nurse cell to oocyte	The directed movement of cytoplasmic constituents synthesized in the nurse cells to the oocyte.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0061564	biolink:NamedThing	axon development	The progression of an axon over time. Covers axonogenesis (de novo generation of an axon) and axon regeneration (regrowth), as well as processes pertaining to the progression of the axon over time (fasciculation and defasciculation).	tmpzr1t_l9r_go_relaxed.owl								dph	2013-07-18T14:43:01Z					biological_process											owl:Class	
GO:0000709	biolink:NamedThing	meiotic joint molecule formation	The conversion of the paired broken DNA and homologous duplex DNA into a four-stranded branched intermediate, known as a joint molecule, formed during meiotic recombination. These joint molecules contain Holliday junctions on either side of heteroduplex DNA.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0014904	biolink:NamedThing	myotube cell development	The process aimed at the progression of a myotube cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0021764	biolink:NamedThing	amygdala development	The progression of the amygdala over time from its initial formation until its mature state. The amygdala is an almond-shaped set of neurons in the medial temporal lobe of the brain that play a key role in processing emotions such as fear and pleasure.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0044671	biolink:NamedThing	sorocarp spore cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a sorocarp spore cell, a cell of the sorocarp sorus. A sorocarp is the fruiting body characteristic of certain cellular slime moulds (e.g., Dictyosteliida) and consists of both stalk and a sorus (spore mass).	tmpzr1t_l9r_go_relaxed.owl								jl	2012-08-08T13:10:48Z					biological_process											owl:Class	
GO:0018989	biolink:NamedThing	apolysis	The first process of molting, characterized by the detachment of the old cuticle from the underlying epidermal cells.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Apolysis									biological_process											owl:Class	
GO:0032002	biolink:NamedThing	interleukin-28 receptor complex	A protein complex that binds interleukin-28 and interleukin-29. It is composed of an alpha and a beta receptor subunit (in human IFNLR1/IL28Ralpha & IL10RB) and either Interleukin-28 (IFNL2 or IFNL3) or Interleukin-29 (IFNL1).	tmpzr1t_l9r_go_relaxed.owl	IL-28 receptor complex													cellular_component											owl:Class	
GO:0007464	biolink:NamedThing	R3/R4 cell fate commitment	The process in which the R3/R4 photoreceptors commit to their cell fate. R3 and R4 are paired photoreceptors which contribute the outer rhabdomeres.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1905349	biolink:NamedThing	ciliary transition zone assembly	The aggregation, arrangement and bonding together of a set of components to form a ciliary transition zone.	tmpzr1t_l9r_go_relaxed.owl	ciliary transition zone formation|cilium transition zone assembly|cilial transition zone assembly|cilial transition zone formation|cilium transition zone formation							pr	2016-08-04T14:49:43Z					biological_process											owl:Class	
GO:1903931	biolink:NamedThing	positive regulation of pyrimidine-containing compound salvage	Any process that activates or increases the frequency, rate or extent of pyrimidine-containing compound salvage.	tmpzr1t_l9r_go_relaxed.owl	up regulation of pyrimidine-containing compound salvage|up-regulation of pyrimidine salvage|upregulation of pyrimidine-containing compound salvage|upregulation of pyrimidine salvage|activation of pyrimidine-containing compound salvage|activation of pyrimidine salvage|up-regulation of pyrimidine-containing compound salvage|positive regulation of pyrimidine salvage|up regulation of pyrimidine salvage							al	2015-02-12T14:09:15Z					biological_process											owl:Class	
GO:0048099	biolink:NamedThing	anterior/posterior lineage restriction, imaginal disc	Formation and/or maintenance of a lineage boundary between anterior and posterior compartments that cells cannot cross, thus separating the populations of cells in each compartment.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0060532	biolink:NamedThing	bronchus cartilage development	The process whose specific outcome is the progression of lung cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate.	tmpzr1t_l9r_go_relaxed.owl	pulmonary cartilage development							dph	2009-04-10T08:12:06Z					biological_process											owl:Class	
GO:0097166	biolink:NamedThing	lens epithelial cell proliferation	The multiplication or reproduction of lens epithelial cells, resulting in the expansion of a cell population. Lens epithelial cells make up the lens epithelium, which is located in the anterior portion of the lens between the lens capsule and the lens fibers and is a simple cuboidal epithelium. The epithelial cells of the lens regulate most of the homeostatic functions of the lens such as osmolarity and liquid volume. The lens epithelial cells also serve as the progenitors for new lens fibers. The lens epithelium constantly lays down fibers in the embryo, fetus, infant, and adult, and continues to lay down fibers for lifelong growth.	tmpzr1t_l9r_go_relaxed.owl								pr	2011-09-29T01:27:50Z					biological_process											owl:Class	
GO:0019432	biolink:NamedThing	triglyceride biosynthetic process	The chemical reactions and pathways resulting in the formation of a triglyceride, any triester of glycerol.	tmpzr1t_l9r_go_relaxed.owl	triglyceride formation|triglyceride biosynthesis|triacylglycerol biosynthetic process|triglyceride anabolism|triacylglycerol biosynthesis|triglyceride synthesis				MetaCyc:TRIGLSYN-PWY									biological_process											owl:Class	
GO:0061705	biolink:NamedThing	sucrose catabolic process to fructose-6-phosphate through glucose and fructose	The chemical reactions and pathways resulting in the breakdown of sucrose, to yield fructose-6-phosphate through both glucose and fructose intermediates.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:PWY-621			dph	2015-06-11T13:32:05Z					biological_process											owl:Class	
GO:0002317	biolink:NamedThing	plasma cell differentiation	The process in which a B cell acquires the specialized features of a plasma cell. A plasma cell is a lymphocyte which develops from a B cell and produces high amounts of antibody.	tmpzr1t_l9r_go_relaxed.owl	plasma cell development					Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.								biological_process											owl:Class	
GO:0008131	biolink:NamedThing	primary amine oxidase activity	Catalysis of the reaction: a primary amine + H2O + O2 = an aldehyde + NH3 + hydrogen peroxide.	tmpzr1t_l9r_go_relaxed.owl	amine oxidase activity|primary-amine:oxygen oxidoreductase (deaminating) activity|amine oxidase (copper-containing) activity				MetaCyc:RXN-9597|Reactome:R-HSA-5696183|KEGG_REACTION:R01853|Reactome:R-HSA-141200|EC:1.4.3.21|Reactome:R-HSA-5603108|Reactome:R-HSA-5696146|Reactome:R-HSA-141186|Reactome:R-HSA-379395|Reactome:R-HSA-374909|Reactome:R-HSA-379382|Reactome:R-HSA-141202							GO:0008122|GO:0004041		molecular_function											owl:Class	
GO:0008494	biolink:NamedThing	translation activator activity	Any of a group of soluble proteins functioning in the activation of ribosome-mediated translation of mRNA into a polypeptide.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0070565	biolink:NamedThing	telomere-telomerase complex	A complex of DNA and protein located at the end of a linear chromosome that enables replication of the telomeric repeat sequences at the end of a linear chromosome.	tmpzr1t_l9r_go_relaxed.owl						Note that this term can be used in place of the obsolete cellular component term 'telomere ; GO:0005696'. Use with caution because this term refers to a specific protein complex and not a region of the chromosome.		mah	2009-04-14T03:07:50Z					cellular_component											owl:Class	
GO:0060966	biolink:NamedThing	regulation of gene silencing by RNA	Any process that regulates the rate, frequency, or extent of gene silencing by RNA. Gene silencing by RNA is the process in which RNA molecules inactivate expression of target genes.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-10-05T03:17:02Z					biological_process											owl:Class	
GO:0045105	biolink:NamedThing	intermediate filament polymerization or depolymerization	Assembly or disassembly of intermediate filaments by the addition or removal of component parts from a filament.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1903949	biolink:NamedThing	positive regulation of atrial cardiac muscle cell action potential	Any process that activates or increases the frequency, rate or extent of atrial cardiac muscle cell action potential.	tmpzr1t_l9r_go_relaxed.owl	activation of atrial cardiac muscle cell action potential|up-regulation of atrial cardiac muscle cell action potential|upregulation of atrial cardiac muscle cell action potential|up regulation of atrial cardiac muscle cell action potential							nc	2015-02-20T14:36:42Z					biological_process											owl:Class	
GO:0060537	biolink:NamedThing	muscle tissue development	The progression of muscle tissue over time, from its initial formation to its mature state. Muscle tissue is a contractile tissue made up of actin and myosin fibers.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-04-10T08:05:37Z					biological_process											owl:Class	
GO:0097342	biolink:NamedThing	ripoptosome	A protein complex whose core components are the receptor-interacting serine/threonine-protein kinases RIPK1 and RIPK3 (also called RIP1 and RIP3). Formation of the ripoptosome can induce an extrinsic apoptotic signaling pathway or a necroptotic signaling pathway. The composition of this protein complex may depend on several factors including nature of the signal, cell type and more.	tmpzr1t_l9r_go_relaxed.owl	TNFR1 complex II|Tnfr1-CII|necrosome					It has been shown that receptor-mediated necroptotic signaling pathway requires assembly of a ripoptosome protein complex consisting of caspase-8, caspase-10, Fas-associated death domain protein (FADD), casp8 and FADD-like apoptosis regulator (CFLAR) as well as the two receptor-interacting serine/threonine-protein kinases RIPK1 and RIPK3 (PMID:21737330). Optionally, depending on the receptor activated, this complex may contain TLR3 adaptor protein TRIF (PMID:21737330).		pr	2012-06-18T12:55:34Z					cellular_component											owl:Class	
GO:0005008	biolink:NamedThing	hepatocyte growth factor-activated receptor activity	Combining with hepatocyte growth factor and transmitting the signal across the plasma membrane to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	hepatocyte growth factor receptor activity|HGF receptor activity|HGF-activated receptor activity					Note that this term represents an activity and not a gene product, and should only be used when the receptor binds the ligand HGF. For receptors that bind other growth factors, consider annotating to other terms under 'transmembrane signaling receptor activity ; GO:0004888.								molecular_function											owl:Class	
GO:0036458	biolink:NamedThing	hepatocyte growth factor binding	Binding to a hepatocyte growth factor.	tmpzr1t_l9r_go_relaxed.owl	HGF binding							bf	2013-12-09T14:07:20Z					molecular_function											owl:Class	
GO:1990475	biolink:NamedThing	synaptic vesicle, recycling pool	A synaptic vesicle belonging to the pool that repopulate vacancies within the readily releasable pool (RRP) of synaptic vesicles, and require more significant stimuli than the RRP in order to release neurotransmitter; about 10-15% of the total number of synaptic vesicles at a resting terminal bouton are in this state.	tmpzr1t_l9r_go_relaxed.owl	recycling pool of synaptic vesicles							pr	2014-09-02T09:08:22Z					cellular_component											owl:Class	
GO:0005931	biolink:NamedThing	axonemal nexin link	A protein complex found in the axoneme of eukaryotic cilia and flagella. It forms interconnections between the microtubule outer doublets that surround the inner central pair of microtubules.	tmpzr1t_l9r_go_relaxed.owl	nexin complex|axonemal interdoublet link													cellular_component											owl:Class	
GO:0021683	biolink:NamedThing	cerebellar granular layer morphogenesis	The process in which the anatomical structure of the cerebellar granular layer is generated and organized. The granular layer is the innermost layer of the cerebellar cortex. This layer contains densely packed small neurons, mostly granule cells. Some Golgi cells are found at the outer border. Granule neurons send parallel fibers to the upper molecular layer, where they synapse with Purkinje cell dendrites. Mossy fibers from the pontine nuclei in the white matter synapse with granule cell axons, Golgi cell axons and unipolar brush interneuron axons at cerebellar glomeruli in the granule cell layer.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0060915	biolink:NamedThing	mesenchymal cell differentiation involved in lung development	The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal cell of the lung. A mesenchymal cell is a loosely associated cell that is part of the connective tissue in an organism. Mesenchymal cells give rise to more mature connective tissue cell types.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-09-18T11:45:33Z					biological_process											owl:Class	
GO:0045009	biolink:NamedThing	chitosome	An intracellular membrane-bounded particle found in fungi and containing chitin synthase; it synthesizes chitin microfibrils. Chitin synthase activity exists in chitosomes and they are proposed to act as a reservoir for regulated transport of chitin synthase enzymes to the division septum.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0048759	biolink:NamedThing	xylem vessel member cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a vessel member cell. A vessel member cell is one of the components of a vessel in the xylem. It is a dead cell with the wall between adjacent members being variously perforated and the walls that persist variously thickened.	tmpzr1t_l9r_go_relaxed.owl	vessel member cell differentiation|vessel element cell differentiation													biological_process											owl:Class	
GO:0071442	biolink:NamedThing	positive regulation of histone H3-K14 acetylation	Any process that activates or increases the frequency, rate or extent of the addition of an acetyl group to histone H3 at position 14 of the histone.	tmpzr1t_l9r_go_relaxed.owl	up regulation of histone H3-K14 acetylation|upregulation of histone H3-K14 acetylation|stimulation of histone H3-K14 acetylation|up-regulation of histone H3-K14 acetylation|activation of histone H3-K14 acetylation|positive regulation of histone H3 acetylation at K14|positive regulation of histone H3K14 acetylation							mah	2009-12-16T03:29:49Z					biological_process											owl:Class	
GO:0043384	biolink:NamedThing	pre-T cell receptor complex	A receptor complex found on immature T cells consisting of a T cell receptor beta chain and the pre-TCR-alpha chain, along with additional signaling components including CD3 family members and additional signaling proteins.	tmpzr1t_l9r_go_relaxed.owl	pre-T-cell receptor complex|pre-TCR complex|pre-T-lymphocyte receptor complex|pre-T lymphocyte receptor complex													cellular_component											owl:Class	
GO:0070898	biolink:NamedThing	RNA polymerase III preinitiation complex assembly	The aggregation, arrangement and bonding together of proteins on promoter DNA to form the transcriptional preinitiation complex (PIC), the formation of which is a prerequisite for transcription from an RNA polymerase III promoter.	tmpzr1t_l9r_go_relaxed.owl	RNA polymerase III transcription PIC formation|RNA polymerase III transcriptional preinitiation complex formation|RNA polymerase III type 3 promoter transcriptional preinitiation complex assembly|RNA polymerase III transcriptional preinitiation complex assembly|RNA polymerase III type 1 promoter transcriptional preinitiation complex assembly|RNA polymerase III transcription PIC biosynthesis|RNA polymerase III hybrid type promoter transcriptional preinitiation complex assembly|RNA polymerase III type 2 promoter transcriptional preinitiation complex assembly							mah	2010-08-19T04:16:04Z			GO:0001021|GO:0001043|GO:0001020|GO:0000999		biological_process											owl:Class	
GO:2000806	biolink:NamedThing	positive regulation of termination of RNA polymerase II transcription, poly(A)-coupled	Any process that activates or increases the frequency, rate or extent of termination of RNA polymerase II transcription, poly(A)-coupled.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of transcription termination from Pol II promoter, poly(A) coupled|positive regulation of transcription termination from Pol II promoter, RNA polymerase(A) coupled|positive regulation of termination of RNA polymerase II transcription, polyadenylation-coupled							pr	2011-07-04T08:41:39Z					biological_process											owl:Class	
GO:1901898	biolink:NamedThing	negative regulation of relaxation of cardiac muscle	Any process that stops, prevents or reduces the frequency, rate or extent of relaxation of cardiac muscle.	tmpzr1t_l9r_go_relaxed.owl	downregulation of relaxation of cardiac muscle|inhibition of relaxation of cardiac muscle|down-regulation of relaxation of cardiac muscle|down regulation of relaxation of cardiac muscle							rl	2013-02-06T21:27:02Z					biological_process											owl:Class	
GO:0060360	biolink:NamedThing	negative regulation of leucine import in response to ammonium ion	Any process that decreases the rate, frequency or extent of leucine import as a result of an ammonium ion stimulus. Leucine import is the directed movement of leucine into a cell or organelle.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of leucine uptake in response to ammonium ion													biological_process											owl:Class	
GO:0070998	biolink:NamedThing	sensory perception of gravity	The series of events required for an organism to receive a gravitational stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-11-03T03:25:12Z					biological_process											owl:Class	
GO:0004918	biolink:NamedThing	interleukin-8 receptor activity	Combining with interleukin-8 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	IL-8 receptor activity|IL-8R													molecular_function											owl:Class	
GO:0021757	biolink:NamedThing	caudate nucleus development	The progression of the caudate nucleus over time from its initial formation until its mature state. The caudate nucleus is the C-shaped structures of the striatum containing input neurons involved with control of voluntary movement in the brain.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0021756	biolink:NamedThing	striatum development	The progression of the striatum over time from its initial formation until its mature state. The striatum is a region of the forebrain consisting of the caudate nucleus, putamen and fundus striati.	tmpzr1t_l9r_go_relaxed.owl	neostriatum development|striate nucleus development													biological_process											owl:Class	
GO:1990411	biolink:NamedThing	hercynylcysteine sulfoxide lyase activity (ergothioneine-forming)	Catalysis of the reaction: hercynylcysteine sulfoxide + 2H+ = ergothioneine + pyruvate + ammonium.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-14428|RHEA:42688			mah	2014-07-02T15:45:43Z					molecular_function											owl:Class	
GO:0048400	biolink:NamedThing	positive regulation of intermediate mesodermal cell fate specification	Any process that activates or increases the frequency, rate or extent of intermediate mesoderm cell fate specification.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of intermediate mesodermal cell fate specification|up regulation of intermediate mesodermal cell fate specification|stimulation of intermediate mesodermal cell fate specification|activation of intermediate mesodermal cell fate specification|upregulation of intermediate mesodermal cell fate specification													biological_process											owl:Class	
GO:0090091	biolink:NamedThing	positive regulation of extracellular matrix disassembly	Any process that increases the rate, frequency or extent of extracellular matrix disassembly. Extracellular matrix disassembly is a process that results in the breakdown of the extracellular matrix.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-11-04T10:03:25Z					biological_process											owl:Class	
GO:2000040	biolink:NamedThing	regulation of planar cell polarity pathway involved in axis elongation	Any process that modulates the frequency, rate or extent of planar cell polarity pathway involved in axis elongation.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-08-18T02:47:49Z					biological_process											owl:Class	
GO:0031162	biolink:NamedThing	sulfur incorporation into metallo-sulfur cluster	The incorporation of exogenous sulfur into a metallo-sulfur cluster.	tmpzr1t_l9r_go_relaxed.owl	sulphur incorporation into metallo-sulphur cluster													biological_process											owl:Class	
GO:0072426	biolink:NamedThing	response to G2 DNA damage checkpoint signaling	A process that occurs in response to signals generated as a result of G2/M transition DNA damage checkpoint signaling.	tmpzr1t_l9r_go_relaxed.owl	G2/M transition DNA damage checkpoint effector process|response to signal involved in G2/M transition DNA damage checkpoint							mah	2010-12-08T04:26:35Z					biological_process											owl:Class	
GO:0098689	biolink:NamedThing	latency-replication decision	The process by which a virus switches on its replication cycle in an infected cell.   The process is typically controlled by a genetic swtich controlled by environmental factors such as cell type, cell shape, the availability of nutrients, superinfection or exposure of infected cells to UV or various chemical stimuli.	tmpzr1t_l9r_go_relaxed.owl	reactivation of latent virus|proviral switch|lytic switch|prophage induction|Latency-replication switch|proviral induction				VZ:3964			dos	2017-02-28T11:24:26Z					biological_process											owl:Class	
GO:1900295	biolink:NamedThing	negative regulation of heptasaccharide transport	Any process that stops, prevents or reduces the frequency, rate or extent of heptasaccharide transport.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of heptasaccharide transport|inhibition of heptasaccharide transport|down regulation of heptasaccharide transport|downregulation of heptasaccharide transport							tt	2012-04-05T07:40:49Z					biological_process											owl:Class	
GO:0097541	biolink:NamedThing	axonemal basal plate	Part of the axoneme consisting of a highly electron-dense region at the distal end of the ciliary transition zone within the axonemal lumen at which the axonemal central pair of microtubules is connected to the rest of the axonemal structure.	tmpzr1t_l9r_go_relaxed.owl	axoneme basal plate|basal plate							pr	2013-12-12T11:10:39Z					cellular_component											owl:Class	
GO:0003291	biolink:NamedThing	atrial septum intermedium morphogenesis	The process in which anatomical structure of an atrial septum intermedium is generated and organized.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-10-20T10:35:04Z					biological_process											owl:Class	
GO:0003286	biolink:NamedThing	atrial septum intermedium development	The progression of the atrial septum intermedium over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-10-20T10:23:52Z					biological_process											owl:Class	
GO:0106172	biolink:NamedThing	COPI-coated vesicle lumen	The volume enclosed by the membrane of a COPI-coated endocytic vesicle.	tmpzr1t_l9r_go_relaxed.owl								hjd	2019-02-11T18:04:08Z					cellular_component											owl:Class	
GO:2000653	biolink:NamedThing	regulation of genetic imprinting	Any process that modulates the frequency, rate or extent of genetic imprinting.	tmpzr1t_l9r_go_relaxed.owl	regulation of DNA imprinting							vk	2011-04-30T02:42:19Z					biological_process											owl:Class	
GO:0008865	biolink:NamedThing	fructokinase activity	Catalysis of the reaction: ATP + D-fructose = ADP + D-fructose 6-phosphate.	tmpzr1t_l9r_go_relaxed.owl	D-fructose(D-mannose)kinase activity|D-fructokinase activity|fructokinase (phosphorylating)|ATP:D-fructose 6-phosphotransferase activity				MetaCyc:FRUCTOKINASE-RXN|RHEA:16125|EC:2.7.1.4									molecular_function											owl:Class	
GO:1902325	biolink:NamedThing	negative regulation of chlorophyll biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of chlorophyll biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	down regulation of chlorophyll biosynthesis|down-regulation of chlorophyll synthesis|down regulation of chlorophyll synthesis|down-regulation of chlorophyll formation|down regulation of chlorophyll biosynthetic process|negative regulation of chlorophyll formation|downregulation of chlorophyll anabolism|downregulation of chlorophyll formation|downregulation of chlorophyll biosynthetic process|down-regulation of chlorophyll biosynthesis|inhibition of chlorophyll formation|inhibition of chlorophyll biosynthesis|down-regulation of chlorophyll biosynthetic process|negative regulation of chlorophyll anabolism|down regulation of chlorophyll anabolism|inhibition of chlorophyll anabolism|down-regulation of chlorophyll anabolism|negative regulation of chlorophyll synthesis|inhibition of chlorophyll synthesis|negative regulation of chlorophyll biosynthesis|down regulation of chlorophyll formation|downregulation of chlorophyll biosynthesis|inhibition of chlorophyll biosynthetic process|downregulation of chlorophyll synthesis							tb	2013-07-24T22:47:29Z					biological_process											owl:Class	
GO:0120107	biolink:NamedThing	bacterial-type flagellum rotor complex	The rotor complex of the bacterial-type flagellum consists of a membrane-anchored ring and the motor switch complex, which participates in the conversion of proton/Na+ energy into the mechanical work of rotation and controls the direction of flagellar rotation.	tmpzr1t_l9r_go_relaxed.owl								krc	2017-10-17T20:54:45Z					cellular_component											owl:Class	
GO:0044476	biolink:NamedThing	envenomation resulting in negative regulation of low voltage-gated calcium channel activity in other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant stopping, prevention or reduction of the activity of a low voltage-gated calcium channel in the bitten organism.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-01-19T02:28:42Z					biological_process											owl:Class	
GO:0035919	biolink:NamedThing	negative regulation of low voltage-gated calcium channel activity in other organism	Any process in which an organism stops, prevents or reduces the frequency, rate or extent of the activity of a low voltage-gated calcium channel in another organism. A low voltage-gated channel is a channel whose open state is dependent on low voltage across the membrane in which it is embedded.	tmpzr1t_l9r_go_relaxed.owl	downregulation of low voltage-gated calcium channel activity in other organism|inhibition of low voltage-gated calcium channel activity in other organism|down-regulation of low voltage-gated calcium channel activity in other organism|negative regulation of low voltage-dependent calcium channel activity in other organism|negative regulation of low voltage gated calcium channel activity in other organism							bf	2011-07-01T11:56:21Z					biological_process											owl:Class	
GO:0015701	biolink:NamedThing	bicarbonate transport	The directed movement of bicarbonate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0036130	biolink:NamedThing	prostaglandin H2 endoperoxidase reductase activity	Catalysis of the reaction: prostaglandin H2 + NADPH + H+ -> prostaglandin F2alpha + NADP+. This reaction is the reduction of prostaglandin H2 ((5Z,13E)-(15S)-9alpha,11alpha-Epidioxy-15-hydroxyprosta-5,13-dienoate) to prostaglandin F2alpha ((5Z,13E)-(15S)-9alpha,11alpha,15-Trihydroxyprosta-5,13-dienoate).	tmpzr1t_l9r_go_relaxed.owl	PGH2 9,11-endoperoxidase|PGH2 9-,11-endoperoxide reductase				RHEA:45312|Reactome:R-HSA-2161549|KEGG_REACTION:R02264			bf	2012-03-05T09:25:03Z					molecular_function											owl:Class	
GO:0002109	biolink:NamedThing	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, LSU-rRNA,5S)	Any process involved in the maturation of a precursor Small SubUnit (SSU) ribosomal RNA (rRNA) molecule into a mature SSU-rRNA molecule from the pre-rRNA molecule originally produced as a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, Large Subunit (LSU) the 5S rRNA in that order from 5' to 3' along the primary transcript.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0035764	biolink:NamedThing	dorsal motor nucleus of vagus nerve formation	The process that gives rise to the dorsal motor nucleus of the vagus nerve. This process pertains to the initial formation of a structure from unspecified parts.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-03-29T02:48:26Z					biological_process											owl:Class	
GO:0098025	biolink:NamedThing	virus tail, baseplate	Multiprotein component at the distal (head) end of the virus tail to which fibers of tailed viruses may be attached.	tmpzr1t_l9r_go_relaxed.owl	bacteriophage baseplate|tail structure|tail tip					Tail fibers are often attached to the baseplate of Caudovirales (tailed bacteriophages with dsDNA genomes). Sometimes referred to as the tail tip or tip structure in Siphoviridae.		bm	2012-07-19T14:16:51Z					cellular_component											owl:Class	
GO:1905344	biolink:NamedThing	prostaglandin catabolic process	The chemical reactions and pathways resulting in the breakdown of prostaglandin.	tmpzr1t_l9r_go_relaxed.owl	prostaglandin degradation|prostaglandin breakdown|prostaglandin catabolism							rl	2016-07-31T08:20:02Z					biological_process											owl:Class	
GO:1902488	biolink:NamedThing	cholangiocyte apoptotic process	Any apoptotic process in a cholangiocyte.	tmpzr1t_l9r_go_relaxed.owl	epithelial cell of bile duct apoptosis|epithelial cell of bile duct apoptotic process|cholangiocyte apoptosis							cls	2013-11-12T15:30:08Z					biological_process											owl:Class	
GO:0030142	biolink:NamedThing	COPI-coated Golgi to ER transport vesicle	A vesicle that mediates transport from the Golgi to the endoplasmic reticulum.	tmpzr1t_l9r_go_relaxed.owl	Golgi-ER transport vesicle|retrograde transport vesicle|Golgi to endoplasmic reticulum transport vesicle|Golgi to ER constitutive secretory pathway transport vesicle|Golgi-endoplasmic reticulum transport vesicle													cellular_component											owl:Class	
GO:0044499	biolink:NamedThing	envenomation resulting in positive regulation of blood pressure in other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant increase of the force with which blood travels through the circulatory system of the bitten/stung organism.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-02-01T02:39:06Z					biological_process											owl:Class	
GO:0044497	biolink:NamedThing	positive regulation of blood pressure in other organism	A process by which one organism increases the force with which blood travels through the circulatory system of another organism.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-02-01T02:17:21Z					biological_process											owl:Class	
GO:0043490	biolink:NamedThing	malate-aspartate shuttle	The process of transferring reducing equivalents from the cytosol into the mitochondria; NADH is used to synthesise malate in the cytosol; this compound is then transported into the mitochondria where it is converted to oxaloacetate using NADH, the oxaloacetate reacts with gluamate to form aspartate, and the aspartate then returns to the cytosol to complete the cycle.	tmpzr1t_l9r_go_relaxed.owl	malate aspartate shuttle|malate:aspartate shuttle|malate/aspartate shuttle				Wikipedia:Malate-aspartate_shuttle									biological_process											owl:Class	
GO:0052776	biolink:NamedThing	diacetylchitobiose catabolic process to glucosamine and acetate	The pathway resulting in the breakdown of diacetylchitobiose into simpler products, including glucosamine and glucosamine. The catabolism proceeds by the deacetylation of diacetylchitobiose, producing acetate and GlcN-GlcNAc; the latter is cleaved to produce glucosamine (GlcN) and N-acetylglucosamine (GlcNAc). The N-acetylglucosamine (GlcNAc) is then deacetylated to produce glucosamine (GlcN) and acetate.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0052773	biolink:NamedThing	diacetylchitobiose deacetylase activity	Catalysis of the reaction: N,N'-diacetylchitobiose (GlcNac2) + H2O = acetate + 2-acetamido-4-O-(2-amino-2-deoxy-beta-D-glucopyranosyl)-2-deoxy-D-glucose (GlcN-GlcNAc).	tmpzr1t_l9r_go_relaxed.owl	N,N'-diacetylchitobiose deacetylase (nonreducing end)				MetaCyc:RXN-12543	In this reaction N,N'-diacetylchitobiose is deacetylated at the non-reducing residue to produce 2-acetamido-4-O-(2-amino-2-deoxy-beta-D-glucopyranosyl)-2-deoxy-D-glucose (GlcN-GlcNAc). This is in contrast to EC:3.5.1.105 in which N,N'-diacetylchitobiose is deacetylated at the reducing residue to produce 4-O-(N-acetyl-beta-D-glucosaminyl)-D-glucosamine (GlcNAc-GlcN). For the latter reaction, see GO:0036311.		ai	2011-10-03T12:01:05Z					molecular_function											owl:Class	
GO:0004839	biolink:NamedThing	ubiquitin activating enzyme activity	Catalysis of the reaction: E1 + ubiquitin + ATP--> E1-ubiquitin + AMP + PPi, where the E1-ubiquitin linkage is a thioester bond between the C-terminal glycine of Ub and a sulfhydryl side group of an E1 cysteine residue. This is the first step in a cascade of reactions in which ubiquitin is ultimately added to a protein substrate.	tmpzr1t_l9r_go_relaxed.owl	E1 ubiquitin-activating enzyme				Reactome:R-HSA-8852134|Reactome:R-HSA-8865050|Reactome:R-HSA-8852133|EC:6.2.1.45|Reactome:R-HSA-8865098|Reactome:R-HSA-8852132|Reactome:R-HSA-8865090	The ubiquitin activating enzyme catalyzes a ligation reaction.								molecular_function											owl:Class	
GO:0070001	biolink:NamedThing	aspartic-type peptidase activity	Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a mechanism in which a water molecule bound by the side chains of aspartic residues at the active center acts as a nucleophile.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0048727	biolink:NamedThing	posterior cibarial plate development	The process whose specific outcome is the progression of the posterior cibarial plate over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0106005	biolink:NamedThing	RNA 5'-cap (guanine-N7)-methylation	The process whereby a guanine in 5-cap is methylated at the N7 position of guanine.	tmpzr1t_l9r_go_relaxed.owl								hjd	2017-04-07T19:19:57Z					biological_process											owl:Class	
GO:0007567	biolink:NamedThing	parturition	The reproductive process in which the parent is separated from its offspring either by giving birth to live young or by laying eggs.	tmpzr1t_l9r_go_relaxed.owl	egg laying|giving birth													biological_process											owl:Class	
GO:0035099	biolink:NamedThing	hemocyte migration	The directed movement of a hemocyte within the embryo. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. In Drosophila, embryonic hemocytes originate from the head mesoderm as a cluster of cells. The cluster splits into two and one group of cells crosses the amnioserosa. Both populations then spread toward the middle of the embryo and then disperse evenly throughout the embryo.	tmpzr1t_l9r_go_relaxed.owl	arthropod blood cell migration|hemocyte cell migration													biological_process											owl:Class	
GO:0048148	biolink:NamedThing	behavioral response to cocaine	Any process that results in a change in the behavior of an organism as a result of a cocaine stimulus.	tmpzr1t_l9r_go_relaxed.owl	behavioural response to cocaine													biological_process											owl:Class	
GO:0120264	biolink:NamedThing	regulation of chromosome attachment to the nuclear envelope	Any process that modulates the frequency, rate, extent or location of chromosome attachment to the nuclear envelope.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/20020						krc	2020-09-29T20:26:49Z					biological_process											owl:Class	
GO:1903370	biolink:NamedThing	positive regulation of foraging behavior	Any process that activates or increases the frequency, rate or extent of foraging behavior.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of foraging behavior|activation of foraging behavior|upregulation of foraging behavior|up regulation of foraging behavior							mr	2014-08-22T03:03:20Z					biological_process											owl:Class	
GO:1903361	biolink:NamedThing	protein localization to basolateral plasma membrane	Any process in which a protein is transported to, or maintained in, basolateral regions of the plasma membrane.	tmpzr1t_l9r_go_relaxed.owl	protein localisation to basolateral plasma membrane|protein localisation in basolateral plasma membrane|protein localization in basolateral plasma membrane|basolateral protein localization							dph	2012-10-19T13:58:04Z			GO:0061467		biological_process											owl:Class	
GO:0106106	biolink:NamedThing	cold-induced thermogenesis	The process by which heat is generated by increasing metabolism in response to cold ambient temperatures in order to maintain a stable core body temperature.	tmpzr1t_l9r_go_relaxed.owl	CIT							hjd	2018-03-21T20:30:52Z					biological_process											owl:Class	
GO:0021615	biolink:NamedThing	glossopharyngeal nerve morphogenesis	The process in which the anatomical structure of the glossopharyngeal nerve is generated and organized. Various sensory and motor branches of the glossopharyngeal nerve supply nerve connections to the pharynx and back of the tongue. The branchial motor component contains motor fibers that innervate muscles that elevate the pharynx and larynx, and the tympanic branch supplies parasympathetic fibers to the otic ganglion.	tmpzr1t_l9r_go_relaxed.owl	CN IX morphogenesis													biological_process											owl:Class	
GO:0014062	biolink:NamedThing	regulation of serotonin secretion	Any process that modulates the frequency, rate or extent of the regulated release of serotonin.	tmpzr1t_l9r_go_relaxed.owl	regulation of serotonin release													biological_process											owl:Class	
GO:1904862	biolink:NamedThing	inhibitory synapse assembly	The aggregation, arrangement and bonding together of a set of components to form an inhibitory synapse.	tmpzr1t_l9r_go_relaxed.owl	inhibitory synapse formation							bf	2015-12-17T10:31:34Z					biological_process											owl:Class	
GO:0005950	biolink:NamedThing	anthranilate synthase complex	A heterotetrameric enzyme complex made up of two components I and two components II. Catalyzes the formation of anthranilate, pyruvate and L-glutamate from chorismate and L-glutamine.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0002432	biolink:NamedThing	granuloma formation	The formation of nodular inflammatory lesions, usually small or granular, firm, persistent, well-structured, and containing compactly grouped T lymphocytes and modified phagocytes such as epithelioid cells, giant cells, and other macrophages. Granuloma formation represents a chronic inflammatory response initiated by various infectious and noninfectious agents. The center of a granuloma consists of fused macrophages, which can become necrotic.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1901426	biolink:NamedThing	response to furfural	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a furfural stimulus.	tmpzr1t_l9r_go_relaxed.owl								tt	2012-10-01T18:45:43Z					biological_process											owl:Class	
GO:0035911	biolink:NamedThing	descending aorta morphogenesis	The process in which the anatomical structures of the descending aorta are generated and organized. The descending aorta is the portion of the aorta in a two-pass circulatory system from the arch of aorta to the point where it divides into the common iliac arteries. In a two-pass circulatory system blood passes twice through the heart to supply the body once.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-06-24T11:19:24Z					biological_process											owl:Class	
GO:0051504	biolink:NamedThing	diterpene phytoalexin precursor biosynthetic process pathway	A branched pathway that produces the precursors to four structurally distinct types of polycyclic diterpenes. The pathway starts with the cyclization of geranylgeranyl diphosphate into ent-copalyl diphosphate and syn-copalyl diphosphate. The catalytic conversion by diterpene cyclases of these two compounds produces the four diterpene hydrocarbons which are precursors to the four structurally distinct classes of diterpene phytoalexins.	tmpzr1t_l9r_go_relaxed.owl	diterpene phytoalexin precursor formation pathway|diterpene phytoalexin precursor synthesis pathway|diterpene phytoalexin precursor anabolism pathway				MetaCyc:PWY-2981									biological_process											owl:Class	
GO:0035724	biolink:NamedThing	CD24 biosynthetic process	The chemical reactions and pathways resulting in the formation of CD24, a CD marker and cell adhesion molecule that occurs on many B-lineage cells and mature granulocytes, and is involved in B cell activation and differentiation as well as T cell co-stimulation.	tmpzr1t_l9r_go_relaxed.owl	CD24 anabolism|CD24 formation|CD24 synthesis|CD24 biosynthesis							bf	2011-03-07T11:32:54Z					biological_process											owl:Class	
GO:1903862	biolink:NamedThing	positive regulation of oxidative phosphorylation	Any process that activates or increases the frequency, rate or extent of oxidative phosphorylation.	tmpzr1t_l9r_go_relaxed.owl	up regulation of respiratory-chain phosphorylation|upregulation of oxidative phosphorylation|up-regulation of respiratory-chain phosphorylation|upregulation of respiratory-chain phosphorylation|up regulation of oxidative phosphorylation|activation of respiratory-chain phosphorylation|activation of oxidative phosphorylation|up-regulation of oxidative phosphorylation|positive regulation of respiratory-chain phosphorylation							sl	2015-02-02T23:40:22Z					biological_process											owl:Class	
GO:0046666	biolink:NamedThing	retinal cell programmed cell death	Programmed cell death that occurs in the developing retina.	tmpzr1t_l9r_go_relaxed.owl	programmed cell death, retinal cells|retina programmed cell death|programmed cell death, retina cells|retinal programmed cell death|retina cell programmed cell death													biological_process											owl:Class	
GO:0097027	biolink:NamedThing	ubiquitin-protein transferase activator activity	Binds to and increases the activity of a ubiquitin-protein transferase, an enzyme that catalyzes the covalent attachment of ubiquitin to lysine in a substrate protein.	tmpzr1t_l9r_go_relaxed.owl								pr	2011-03-31T05:19:23Z					molecular_function											owl:Class	
GO:0019959	biolink:NamedThing	interleukin-8 binding	Binding to interleukin-8.	tmpzr1t_l9r_go_relaxed.owl	IL-8 binding													molecular_function											owl:Class	
GO:2001271	biolink:NamedThing	negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis	Any process that stops, prevents or reduces the frequency, rate or extent of cysteine-type endopeptidase activity involved in execution phase of apoptosis.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of effector caspase activity							pr	2011-12-13T07:59:42Z					biological_process											owl:Class	
GO:0021673	biolink:NamedThing	rhombomere 7 formation	The process that gives rise to rhombomere 7. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0090250	biolink:NamedThing	cell-cell adhesion involved in establishment of planar polarity	The attachment of one cell to another cell via adhesion molecules that contributes to the establishment of planar cell polarity.	tmpzr1t_l9r_go_relaxed.owl								tb	2010-01-22T11:28:03Z					biological_process											owl:Class	
GO:0004909	biolink:NamedThing	interleukin-1, type I, activating receptor activity	Combining with interleukin-1 to initiate a change in cell activity via signaling pathways and mediated by adaptor proteins.	tmpzr1t_l9r_go_relaxed.owl	interleukin-1 activating receptor activity|IL-1 type I, activating receptor|interleukin-1 type I receptor activity|IL-1 type I, activating binding|interleukin-1, type I, activating binding											GO:0019967		molecular_function											owl:Class	
GO:0001614	biolink:NamedThing	purinergic nucleotide receptor activity	Combining with a purine nucleotide and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	purinoceptor|P2 receptor|purinoreceptor|purinergic receptor activity							bf	2010-10-22T10:57:12Z			GO:0035586		molecular_function											owl:Class	
GO:0061860	biolink:NamedThing	DNA clamp unloader activity	Facilitating the opening of the ring structure of the PCNA complex, or any of the related sliding clamp complexes, and their removal from the DNA duplex, driven by ATP hydrolysis.	tmpzr1t_l9r_go_relaxed.owl								dph	2017-04-03T11:49:46Z					molecular_function											owl:Class	
GO:0042949	biolink:NamedThing	arbutin transport	The directed movement of arbutin, a glycoside found in the bearberry and related plants which has been used to treat urinary-tract diseases, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0021718	biolink:NamedThing	superior olivary nucleus development	The process whose specific outcome is the progression of the superior olivary nucleus over time, from its formation to the mature structure. In mice, the superior olivary nucleus is a small cylindrical mass on the dorsal surface of the lateral part of the trapezoid body of the pons, and it is situated immediately above the inferior olivary nucleus. It receives projections from the cochlear nucleus and thus is involved in the perception of sound.	tmpzr1t_l9r_go_relaxed.owl	superior olive development													biological_process											owl:Class	
GO:0035800	biolink:NamedThing	deubiquitinase activator activity	Binds to and increases the activity of deubiquitinase, an enzyme that catalyzes the hydrolysis of various forms of polymeric ubiquitin sequences.	tmpzr1t_l9r_go_relaxed.owl									2011-04-18T10:20:15Z					molecular_function											owl:Class	
GO:0044748	biolink:NamedThing	3'-5'-exoribonuclease activity involved in mature miRNA 3'-end processing	Catalysis of the sequential cleavage of mononucleotides from a free 3' terminus of an RNA molecule that contributes to forming distinct miRNA isoforms from a mature miRNA.	tmpzr1t_l9r_go_relaxed.owl	exonucleolytic trimming to generate 3' end of miRNA							jl	2012-11-20T13:48:29Z					molecular_function											owl:Class	
GO:0045266	biolink:NamedThing	plasma membrane proton-transporting ATP synthase, stator stalk	One of two stalks that connect the catalytic core of the hydrogen-transporting ATP synthase to the plasma membrane-associated F0 proteins; is thought to prevent futile rotation of the catalytic core. Examples of this component are found in Bacterial species.	tmpzr1t_l9r_go_relaxed.owl	proton-transporting ATP synthase, stator stalk|hydrogen-transporting ATP synthase, stator stalk													cellular_component											owl:Class	
GO:0090598	biolink:NamedThing	male anatomical structure morphogenesis	The processes by which anatomical structures that are only present in the male organism are generated and organized.	tmpzr1t_l9r_go_relaxed.owl								tb	2014-08-22T13:29:45Z					biological_process											owl:Class	
GO:0072093	biolink:NamedThing	metanephric renal vesicle formation	The developmental process pertaining to the initial formation of the metanephros.	tmpzr1t_l9r_go_relaxed.owl	metanephros formation							mah	2010-02-10T01:17:11Z					biological_process											owl:Class	
GO:0021771	biolink:NamedThing	lateral geniculate nucleus development	The progression of the lateral geniculate nucleus over time from its initial formation until its mature state. The lateral geniculate nucleus is the primary processor of visual information received from the retina.	tmpzr1t_l9r_go_relaxed.owl	LGN development													biological_process											owl:Class	
GO:0048899	biolink:NamedThing	anterior lateral line development	The process whose specific outcome is the progression of the anterior lateral line over time, from its formation to the mature structure. The anterior lateral line consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the head of all fishes and most amphibians. The anterior lateral line develops from cranial ectodermal placodes situated between the eye and ear.	tmpzr1t_l9r_go_relaxed.owl	anterior LL development													biological_process											owl:Class	
GO:0016358	biolink:NamedThing	dendrite development	The process whose specific outcome is the progression of the dendrite over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0009945	biolink:NamedThing	radial axis specification	The establishment, maintenance and elaboration of an axis that initiates at a point and radiates outward from the point.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0010892	biolink:NamedThing	positive regulation of mitochondrial translation in response to stress	Any process that activates or increases the frequency, rate or extent of mitochondrial translation as a result of a stimulus indicating the organism is under stress.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0061382	biolink:NamedThing	Malpighian tubule tip cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a Malpighian tubule tip cell. A Malpighian tubule tip cell is a mitogenic signaling cell that controls the proliferation of its neighboring cells.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-11-23T09:52:44Z					biological_process											owl:Class	
GO:0061219	biolink:NamedThing	mesonephric mesenchyme development	The biological process whose specific outcome is the progression of a mesonephric mesenchyme from an initial condition to its mature state. This process begins with the formation of mesonephric mesenchyme and ends with the mature structure. Mesonephric mesenchyme is the tissue made up of loosely connected mesenchymal cells in the mesonephros.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-08-17T03:45:44Z					biological_process											owl:Class	
GO:0106037	biolink:NamedThing	apicomedial cortex	The region that lies just beneath the plasma membrane in the middle of the apical edge of a cell.	tmpzr1t_l9r_go_relaxed.owl	medioapical cortex							hjd	2017-07-12T16:59:52Z					cellular_component											owl:Class	
GO:0000390	biolink:NamedThing	spliceosomal complex disassembly	Disassembly of a spliceosomal complex with the ATP-dependent release of the product RNAs, one of which is composed of the joined exons. In cis splicing, the other product is the excised sequence, often a single intron, in a lariat structure.	tmpzr1t_l9r_go_relaxed.owl	U2-type spliceosome disassembly|spliceosome complex disassembly|spliceosome disassembly|U12-type spliceosome disassembly											GO:0000392|GO:0000391		biological_process											owl:Class	
GO:0099042	biolink:NamedThing	nucleation of clathrin-coated pit	The first step in clathrin-dependent endocytosis: invagination of the plasma membrane to form a pit.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0014802	biolink:NamedThing	terminal cisterna	The portion of sarcoplasmic reticulum devoted to calcium ion storage and calcium ion release.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Terminal_cisterna									cellular_component											owl:Class	
GO:0019037	biolink:NamedThing	viral assembly intermediate	Specific locations and structures in the virus infected cell involved in assembling new virions.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:1990144	biolink:NamedThing	intrinsic apoptotic signaling pathway in response to hypoxia	A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced in response to hypoxia (lowered oxygen tension). Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level. The pathway ends when the execution phase of apoptosis is triggered.	tmpzr1t_l9r_go_relaxed.owl								pr	2013-07-23T10:18:10Z					biological_process											owl:Class	
GO:0090740	biolink:NamedThing	integral component of pigment granule membrane	The component of the pigment granule membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.	tmpzr1t_l9r_go_relaxed.owl								tb	2017-05-16T17:48:35Z					cellular_component											owl:Class	
GO:0005797	biolink:NamedThing	Golgi medial cisterna	The middle Golgi cisterna (or cisternae).	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0061844	biolink:NamedThing	antimicrobial humoral immune response mediated by antimicrobial peptide	An immune response against microbes mediated by anti-microbial peptides in body fluid.	tmpzr1t_l9r_go_relaxed.owl	antimicrobial peptide-mediated antimicrobial humoral response|peptide-mediated antimicrobial humoral response													biological_process											owl:Class	
GO:0003432	biolink:NamedThing	cell growth involved in growth plate cartilage chondrocyte morphogenesis	The growth of a growth plate cartilage chondrocyte, where growth contributes to the shaping of the chondrocyte over time.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-12-22T12:37:48Z					biological_process											owl:Class	
GO:0140235	biolink:NamedThing	RNA polyadenylation at postsynapse	A polyadenylation event (the enzymatic addition of a sequence of adenylyl residues at the 3' end of an RNA molecule) that takes place at a postsynapse.	tmpzr1t_l9r_go_relaxed.owl						Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.		pg	2018-07-13T12:03:28Z					biological_process											owl:Class	
GO:0097734	biolink:NamedThing	extracellular exosome biogenesis	The assembly and secretion of an extracellular exosome, a membrane-bounded vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane.	tmpzr1t_l9r_go_relaxed.owl	exosome biogenesis|exosome production|ILV assembly|intraluminal vesicle assembly|exosome assembly or secretion							pr	2016-10-03T14:35:25Z					biological_process											owl:Class	
GO:0002075	biolink:NamedThing	somitomeric trunk muscle development	The process whose specific outcome is the progression of the somitomeric trunk muscle over time, from its formation to the mature structure. The somitomeric trunk muscle is derived from somitomeric mesoderm. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle. An example of this process is found in Mus musculus.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0004124	biolink:NamedThing	cysteine synthase activity	Catalysis of the reaction: O3-acetyl-L-serine + hydrogen sulfide = L-cysteine + acetate.	tmpzr1t_l9r_go_relaxed.owl	O-acetyl-L-serine sulfohydrolase activity|O-acetyl-L-serine sulfhydrylase activity|O3-acetyl-L-serine:hydrogen-sulfide 2-amino-2-carboxyethyltransferase activity|O3-acetyl-L-serine acetate-lyase (adding hydrogen-sulfide)|O-acetylserine (thiol)-lyase activity|3-O-acetyl-L-serine:hydrogen-sulfide 2-amino-2-carboxyethyltransferase activity|O-acetylserine sulfhydrylase activity|OAS sulfhydrylase activity|O-acetylserine (thiol)-lyase A activity|acetylserine sulfhydrylase activity|O(3)-acetyl-L-serine acetate-lyase (adding hydrogen-sulfide) activity|cysteine synthetase activity				MetaCyc:ACSERLY-RXN|EC:2.5.1.47|RHEA:14829	Note that this function was formerly 4.2.99.8.								molecular_function											owl:Class	
GO:0038102	biolink:NamedThing	activin receptor antagonist activity	Interacting with an activin receptor complex to reduce the action of another ligand, the agonist. A receptor antagonist does not initiate signaling upon binding to a receptor, but instead blocks an agonist from binding to the receptor.	tmpzr1t_l9r_go_relaxed.owl						This term refers to inhibition of a member of the activin receptor family; activin receptors bind to multiple ligands including activin and nodal.		bf	2012-02-17T11:28:59Z					molecular_function											owl:Class	
GO:0090289	biolink:NamedThing	regulation of osteoclast proliferation	Any process that modulates the rate, frequency, or extent of the multiplication or reproduction of osteoclasts, resulting in the expansion of an osteoclast cell population.	tmpzr1t_l9r_go_relaxed.owl								tb	2010-02-18T03:11:03Z					biological_process											owl:Class	
GO:0036018	biolink:NamedThing	cellular response to erythropoietin	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an erythropoietin stimulus.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-10-12T10:12:18Z					biological_process											owl:Class	
GO:2000989	biolink:NamedThing	negative regulation of hemicellulose catabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of hemicellulose catabolic process.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of hemicellulose catabolism							tt	2011-08-08T03:08:20Z					biological_process											owl:Class	
GO:0031902	biolink:NamedThing	late endosome membrane	The lipid bilayer surrounding a late endosome.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0001787	biolink:NamedThing	natural killer cell proliferation	The expansion of a natural killer cell population by cell division.	tmpzr1t_l9r_go_relaxed.owl	NK cell proliferation													biological_process											owl:Class	
GO:0035987	biolink:NamedThing	endodermal cell differentiation	The process in which a relatively unspecialized cell acquires the specialized features of an endoderm cell, a cell of the inner of the three germ layers of the embryo.	tmpzr1t_l9r_go_relaxed.owl	endoderm cell differentiation							bf	2011-08-25T04:50:36Z					biological_process											owl:Class	
GO:0035694	biolink:NamedThing	mitochondrial protein catabolic process	The chemical reactions and pathways resulting in the breakdown of a mitochondrial protein. This process is necessary to maintain the healthy state of mitochondria and is thought to occur via the induction of an intramitochondrial lysosome-like organelle that acts to eliminate the damaged oxidised mitochondrial proteins without destroying the mitochondrial structure.	tmpzr1t_l9r_go_relaxed.owl	catabolism of mitochondrial protein|degradation of damaged mitochondrial protein							bf	2011-02-28T11:06:40Z					biological_process											owl:Class	
GO:2000535	biolink:NamedThing	regulation of entry of bacterium into host cell	Any process that modulates the frequency, rate or extent of entry of bacterium into host cell.	tmpzr1t_l9r_go_relaxed.owl	regulation of bacterial entry into host cell|regulation of invasion of bacteria into host cell							ebc	2011-03-28T09:52:16Z					biological_process											owl:Class	
GO:0010950	biolink:NamedThing	positive regulation of endopeptidase activity	Any process that increases the frequency, rate or extent of endopeptidase activity, the endohydrolysis of peptide bonds within proteins.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-04-27T11:45:39Z					biological_process											owl:Class	
GO:0004367	biolink:NamedThing	glycerol-3-phosphate dehydrogenase [NAD+] activity	Catalysis of the reaction: sn-glycerol 3-phosphate + NAD+ = glycerone phosphate + NADH + H+.	tmpzr1t_l9r_go_relaxed.owl	L-glycerol phosphate dehydrogenase activity|NAD-alpha-glycerophosphate dehydrogenase activity|alpha-glycerol phosphate dehydrogenase (NAD) activity|NAD-dependent glycerol-3-phosphate dehydrogenase activity|L-glycerophosphate dehydrogenase activity|NAD-L-glycerol-3-phosphate dehydrogenase activity|NAD-dependent glycerol phosphate dehydrogenase activity|glycerol 1-phosphate dehydrogenase activity|L-alpha-glycerophosphate dehydrogenase activity|L-alpha-glycerol phosphate dehydrogenase activity|glycerol-3-phosphate dehydrogenase (NAD) activity|glycerophosphate dehydrogenase (NAD) activity|hydroglycerophosphate dehydrogenase activity|NADH-dihydroxyacetone phosphate reductase activity|NAD-linked glycerol 3-phosphate dehydrogenase activity|alpha-glycerophosphate dehydrogenase (NAD) activity|glycerol phosphate dehydrogenase (NAD) activity				RHEA:11092|Reactome:R-HSA-75889|KEGG_REACTION:R00842|MetaCyc:1.1.1.8-RXN|EC:1.1.1.8									molecular_function											owl:Class	
GO:0043973	biolink:NamedThing	histone H3-K4 acetylation	The modification of histone H3 by the addition of an acetyl group to a lysine residue at position 4 of the histone.	tmpzr1t_l9r_go_relaxed.owl	histone H3K4 acetylation|histone H3 acetylation at K4													biological_process											owl:Class	
GO:0060439	biolink:NamedThing	trachea morphogenesis	The process in which a trachea is generated and organized. The trachea is the portion of the airway that attaches to the bronchi as it branches.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0032169	biolink:NamedThing	prospore septin ring	A tight ring-shaped structure that forms in the division plane at the site of cytokinesis in a prospore; composed of septins as well as septin-associated proteins.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0033616	biolink:NamedThing	plasma membrane proton-transporting ATP synthase complex assembly	The aggregation, arrangement and bonding together of a proton-transporting ATP synthase in the plasma membrane.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0120075	biolink:NamedThing	positive regulation of endocardial cushion cell differentiation	Any process that activates or increases the frequency, rate or extent of endocardial cushion cell differentiation.	tmpzr1t_l9r_go_relaxed.owl								krc	2017-06-26T23:36:59Z					biological_process											owl:Class	
GO:0036063	biolink:NamedThing	acroblast	A cone-shaped structure in the head of a spermatozoon, which is formed by the coalescence of Golgi fragments following the completion of meiosis. The acroblast is situated adjacent to the acrosomal vesicle.	tmpzr1t_l9r_go_relaxed.owl	spermatid acroblast					See also the fly_anatomy.ontology term 'acroblast ; FBbt:00004947'.		bf	2011-12-14T02:29:05Z					cellular_component											owl:Class	
GO:0038132	biolink:NamedThing	neuregulin binding	Binding to a neuregulin, a member of the EGF family of growth factors.	tmpzr1t_l9r_go_relaxed.owl								bf	2012-03-30T10:59:56Z					molecular_function											owl:Class	
GO:0002617	biolink:NamedThing	negative regulation of macrophage antigen processing and presentation	Any process that stops, prevents, or reduces the frequency, rate, or extent of macrophage antigen processing and presentation.	tmpzr1t_l9r_go_relaxed.owl	inhibition of macrophage antigen processing and presentation|downregulation of macrophage antigen processing and presentation|down regulation of macrophage antigen processing and presentation|down-regulation of macrophage antigen processing and presentation													biological_process											owl:Class	
GO:0031422	biolink:NamedThing	RecQ family helicase-topoisomerase III complex	A complex containing a RecQ family helicase and a topoisomerase III homologue (a member of the topoisomerase type IA subfamily); may also include one or more additional proteins; conserved from E. coli to human.	tmpzr1t_l9r_go_relaxed.owl	RecQ helicase-Topo III complex|Sgs1-Top3 complex													cellular_component											owl:Class	
GO:0004170	biolink:NamedThing	dUTP diphosphatase activity	Catalysis of the reaction: dUTP + H2O = dUMP + diphosphate.	tmpzr1t_l9r_go_relaxed.owl	deoxyuridine-triphosphatase activity|dUTPase activity|dUTP nucleotidohydrolase activity|desoxyuridine 5'-triphosphate nucleotidohydrolase activity|desoxyuridine 5'-triphosphatase activity|dUTP pyrophosphatase activity				RHEA:10248|KEGG_REACTION:R02100|MetaCyc:DUTP-PYROP-RXN|EC:3.6.1.23|Reactome:R-HSA-73666									molecular_function											owl:Class	
GO:0042551	biolink:NamedThing	neuron maturation	A developmental process, independent of morphogenetic (shape) change, that is required for a neuron to attain its fully functional state.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0032902	biolink:NamedThing	nerve growth factor production	The appearance of nerve growth factor (NGF) due to biosynthesis or secretion by cells in a neuron's target field, resulting in an increase in its intracellular or extracellular levels.	tmpzr1t_l9r_go_relaxed.owl	NGF production|beta-nerve growth factor production													biological_process											owl:Class	
GO:1902440	biolink:NamedThing	protein localization to mitotic spindle pole body	A process in which a protein is transported to, or maintained in, a location within a mitotic spindle pole body.	tmpzr1t_l9r_go_relaxed.owl	protein localisation in mitotic spindle pole body|protein localisation to mitotic spindle pole body|protein localization in mitotic spindle pole body|establishment of protein localization to mitotic spindle pole body							mah	2013-10-10T14:44:55Z			GO:1990975		biological_process											owl:Class	
GO:0048483	biolink:NamedThing	autonomic nervous system development	The process whose specific outcome is the progression of the autonomic nervous system over time, from its formation to the mature structure. The autonomic nervous system is composed of neurons that are not under conscious control, and is comprised of two antagonistic components, the sympathetic and parasympathetic nervous systems. The autonomic nervous system regulates key functions including the activity of the cardiac (heart) muscle, smooth muscles (e.g. of the gut), and glands.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0007403	biolink:NamedThing	glial cell fate determination	The cell fate determination process in which a cell becomes capable of differentiating autonomously into a glial cell regardless of its environment; upon determination, the cell fate cannot be reversed.	tmpzr1t_l9r_go_relaxed.owl												GO:0043361		biological_process											owl:Class	
GO:0043117	biolink:NamedThing	positive regulation of vascular permeability	Any process that increases the extent to which blood vessels can be pervaded by fluid.	tmpzr1t_l9r_go_relaxed.owl	up regulation of vascular permeability|up-regulation of vascular permeability|activation of vascular permeability|stimulation of vascular permeability|upregulation of vascular permeability													biological_process											owl:Class	
GO:0001829	biolink:NamedThing	trophectodermal cell differentiation	The process in which a relatively unspecialized cell acquires the specialized features of a trophectoderm cell.	tmpzr1t_l9r_go_relaxed.owl	trophectoderm cell differentiation					See also the Anatomical Dictionary for Mouse Development ontology terms 'TS4, trophectoderm ; EMAP:19'.								biological_process											owl:Class	
GO:0044814	biolink:NamedThing	glycolytic fermentation via PFL pathway	The glycolytic fermentation beginning with the anaerobic conversion of glucose to pyruvate by the glycolytic pathway, followed by pyruvate:formate lyase (PFL) activity. This pathway is found in facultative anaerobes such as E. coli.	tmpzr1t_l9r_go_relaxed.owl								jl	2013-09-18T16:56:02Z					biological_process											owl:Class	
GO:0002248	biolink:NamedThing	connective tissue replacement involved in inflammatory response wound healing	The series of events leading to growth of connective tissue when loss of tissues that are incapable of regeneration occurs, or when fibrinous exudate cannot be adequately cleared that contribute to an inflammatory response.	tmpzr1t_l9r_go_relaxed.owl	fibrosis during inflammatory response|connective tissue replacement during inflammatory response													biological_process											owl:Class	
GO:0003043	biolink:NamedThing	vasoconstriction of artery involved in aortic body chemoreceptor response to lowering of systemic arterial blood pressure	A process that is triggered by aortic body-vasomotor excitation and results in a decrease in the diameter of an artery during the chemoreceptor response to decreased blood pressure.	tmpzr1t_l9r_go_relaxed.owl	vasoconstriction of artery during aortic body chemoreceptor response to lowering of systemic arterial blood pressure													biological_process											owl:Class	
GO:0072066	biolink:NamedThing	prebend segment development	The process whose specific outcome is the progression of the prebend segment over time, from its formation to the mature structure. The prebend segment is a part of the descending thin limb that lies before the bend and exhibits permeabilities characteristic of the ascending limb, especially negligible water permeability.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-01-25T04:14:02Z					biological_process											owl:Class	
GO:0034150	biolink:NamedThing	toll-like receptor 6 signaling pathway	Any series of molecular signals generated as a consequence of binding to toll-like receptor 6.	tmpzr1t_l9r_go_relaxed.owl	TLR6 signaling pathway|toll-like receptor 6 signalling pathway													biological_process											owl:Class	
GO:0007195	biolink:NamedThing	adenylate cyclase-inhibiting dopamine receptor signaling pathway	The series of molecular signals generated as a consequence of a dopamine receptor binding to its physiological ligand, where the pathway proceeds with inhibition of adenylyl cyclase and a subsequent decrease in the concentration of cyclic AMP (cAMP).	tmpzr1t_l9r_go_relaxed.owl	inhibition of adenylate cyclase activity by dopamine receptor signalling pathway|inhibition of adenylate cyclase activity by dopamine receptor signaling pathway|dopamine receptor, adenylate cyclase inhibiting pathway|dopamine receptor, adenylyl cyclase inhibiting pathway													biological_process											owl:Class	
GO:1990098	biolink:NamedThing	core primosome complex	A protein-DNA complex containing at least one DNA helicase and one primase. Can also contain associated proteins. The helicase component continues to unwind the double-stranded DNA (dsDNA) and the primase component synthesizes a RNA primer during initiation or restart of replication.	tmpzr1t_l9r_go_relaxed.owl	core primosome					The core primosome refers to a helicase-primase complex, and should not be confused with the more general GO term 'primosome complex ; GO:1990077'.		bhm	2013-05-14T10:30:02Z					cellular_component											owl:Class	
GO:0048323	biolink:NamedThing	axial mesodermal cell fate determination	The process in which a cell becomes capable of differentiating autonomously into an axial mesoderm cell regardless of its environment; upon determination, the cell fate cannot be reversed.	tmpzr1t_l9r_go_relaxed.owl	axial mesoderm cell fate determination													biological_process											owl:Class	
GO:0098694	biolink:NamedThing	regulation of synaptic vesicle budding from presynaptic endocytic zone membrane	Any process that modulates the frequency, rate or extent of synaptic vesicle budding from presynaptic endocytic zone membrane.	tmpzr1t_l9r_go_relaxed.owl								dos	2017-04-04T17:03:29Z					biological_process											owl:Class	
GO:0015349	biolink:NamedThing	thyroid hormone transmembrane transporter activity	Enables the transfer of thyroid hormones from one side of a membrane to the other. Thyroid hormone are any of the compounds secreted by the thyroid gland, largely thyroxine and triiodothyronine.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-9631987|Reactome:R-HSA-879575									molecular_function											owl:Class	
GO:0070327	biolink:NamedThing	thyroid hormone transport	The directed movement of thyroid hormone into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	triiodothyronine transport|thyroxine transport													biological_process											owl:Class	
GO:0000093	biolink:NamedThing	mitotic telophase	The cell cycle phase which follows anaphase during M phase of mitosis and during which the chromosomes arrive at the poles of the cell and the division of the cytoplasm starts.	tmpzr1t_l9r_go_relaxed.owl						Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).								biological_process											owl:Class	
GO:0033215	biolink:NamedThing	reductive iron assimilation	A process in which iron is solubilized by reduction from Fe3+ to Fe2+ via a cell surface reductase and subsequent transport of the iron across the membrane by iron uptake proteins.	tmpzr1t_l9r_go_relaxed.owl	iron assimilation by reduction and transport													biological_process											owl:Class	
GO:2001266	biolink:NamedThing	Roundabout signaling pathway involved in axon guidance	Any Roundabout signaling pathway that is involved in axon guidance.	tmpzr1t_l9r_go_relaxed.owl	ROBO/SLIT signaling pathway involved in axon chemotaxis|Roundabout signaling pathway involved in axon growth cone guidance|Roundabout signalling pathway involved in axon pathfinding|Roundabout signalling pathway involved in axon guidance|ROBO signaling pathway involved in axon guidance|ROBO/SLIT signaling pathway involved in axon guidance|ROBO signaling pathway involved in axon pathfinding|ROBO/SLIT signaling pathway involved in axon pathfinding|Roundabout signaling pathway involved in axon chemotaxis|ROBO signaling pathway involved in axon chemotaxis|Roundabout signalling pathway involved in axon growth cone guidance|ROBO signaling pathway involved in axon growth cone guidance|Roundabout signalling pathway involved in axon chemotaxis|Roundabout signaling pathway involved in axon pathfinding|ROBO/SLIT signaling pathway involved in axon growth cone guidance							bf	2011-12-12T03:40:20Z					biological_process											owl:Class	
GO:0090651	biolink:NamedThing	apical cytoplasm	The region of the cytoplasm located at the apical side of the cell. Used in reference to animal polarized epithelial cells.	tmpzr1t_l9r_go_relaxed.owl								tb	2015-07-01T15:46:19Z					cellular_component											owl:Class	
GO:0086059	biolink:NamedThing	voltage-gated calcium channel activity involved SA node cell action potential	Enables the transmembrane transfer of a calcium ion by a voltage-gated channel across the plasma membrane of an SA node cardiac muscle cell that contributes to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.	tmpzr1t_l9r_go_relaxed.owl	voltage-gated calcium channel activity involved in SAN cardiac muscle cell action potential|voltage-gated calcium channel activity involved in sinus node cardiac muscle cell action potential|voltage-gated calcium channel activity involved in sinoatrial node cardiac muscle cell action potential|voltage-gated calcium channel activity involved in SA node cardiac muscle cell action potential							dph	2011-11-17T12:39:27Z					molecular_function											owl:Class	
GO:0072068	biolink:NamedThing	late distal convoluted tubule development	The process whose specific outcome is the progression of the late distal convoluted tubule over time, from its formation to the mature structure. The late distal convoluted tubule contains DCT cells and intercalated (IC) alpha and beta cells and is vasopressin-sensitive.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-01-25T04:15:50Z					biological_process											owl:Class	
GO:0042672	biolink:NamedThing	retinal cone cell fate specification	The process in which a cell becomes capable of differentiating autonomously into a retinal cone cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0009863	biolink:NamedThing	salicylic acid mediated signaling pathway	A series of molecular signals mediated by salicylic acid.	tmpzr1t_l9r_go_relaxed.owl	salicylic acid mediated signal transduction|salicylic acid mediated signalling pathway|salicylic acid-mediated signaling pathway													biological_process											owl:Class	
GO:1902626	biolink:NamedThing	assembly of large subunit precursor of preribosome	The aggregation, arrangement and bonding together of a set of components to form the large subunit precursor of the preribosome.	tmpzr1t_l9r_go_relaxed.owl	66S preribosome formation|preribosome, large subunit precursor formation|66S preribosome assembly							tb	2014-01-16T19:38:05Z					biological_process											owl:Class	
GO:0061347	biolink:NamedThing	planar cell polarity pathway involved in outflow tract morphogenesis	The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors including C-Jun N-terminal kinase (JNK) to modulate cytoskeletal elements and control cell polarity that contributes to the shaping of the outflow tract.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-10-01T10:38:56Z					biological_process											owl:Class	
GO:0003242	biolink:NamedThing	cardiac chamber ballooning	The morphogenic growth in which the chambers of the heart expand in size, contributing to their shaping.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-10-13T11:30:30Z					biological_process											owl:Class	
GO:0043577	biolink:NamedThing	chemotropism	The movement of an organism, or part of an organism, in response to an external chemical gradient, usually toward or away from it.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Chemotropism									biological_process											owl:Class	
GO:0021631	biolink:NamedThing	optic nerve morphogenesis	The process in which the anatomical structure of the optic nerve is generated and organized. The sensory optic nerve originates from the bipolar cells of the retina and conducts visual information to the brainstem. The optic nerve exits the back of the eye in the orbit, enters the optic canal, and enters the central nervous system at the optic chiasm (crossing) where the nerve fibers become the optic tract just prior to entering the hindbrain.	tmpzr1t_l9r_go_relaxed.owl	CN II morphogenesis													biological_process											owl:Class	
GO:0021969	biolink:NamedThing	corticospinal neuron axon guidance through the cerebral peduncle	The process in which the migration of an axon growth cone of a pyramidal cell that is part of the corticospinal tract is directed after exiting the internal capsule through the cerebral peduncle in response to a combination of attractive and repulsive cues.	tmpzr1t_l9r_go_relaxed.owl	corticospinal neuron axon pathfinding through the cerebral peduncle													biological_process											owl:Class	
GO:0032488	biolink:NamedThing	Cdc42 protein signal transduction	A series of molecular signals within the cell that are mediated by the Cdc42 protein switching to a GTP-bound active state.	tmpzr1t_l9r_go_relaxed.owl	Cdc42 signaling|Cdc42 signaling pathway|cdc42 signalling pathway													biological_process											owl:Class	
GO:0030504	biolink:NamedThing	inorganic diphosphate transmembrane transporter activity	Enables the transfer of inorganic diphosphate across a membrane.	tmpzr1t_l9r_go_relaxed.owl	inorganic pyrophosphate transporter activity				Reactome:R-HSA-5226964									molecular_function											owl:Class	
GO:0061151	biolink:NamedThing	BMP signaling pathway involved in renal system segmentation	A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, which contributes to the segmentation of the renal system.	tmpzr1t_l9r_go_relaxed.owl	BMP signalling pathway involved in renal system segmentation							dph	2010-06-02T09:29:43Z					biological_process											owl:Class	
GO:0004357	biolink:NamedThing	glutamate-cysteine ligase activity	Catalysis of the reaction: L-cysteine + L-glutamate + ATP = L-gamma-glutamyl-L-cysteine + ADP + 2 H(+) + phosphate.	tmpzr1t_l9r_go_relaxed.owl	gamma-glutamyl-L-cysteine synthetase activity|L-glutamate:L-cysteine gamma-ligase (ADP-forming) activity|gamma-glutamylcysteine synthetase activity|gamma-glutamylcysteinyl synthetase activity				Reactome:R-HSA-174367|MetaCyc:GLUTCYSLIG-RXN|RHEA:13285|Reactome:R-HSA-5602892|EC:6.3.2.2|KEGG_REACTION:R00894									molecular_function											owl:Class	
GO:0048291	biolink:NamedThing	isotype switching to IgG isotypes	The switching of activated B cells from IgM biosynthesis to biosynthesis of an IgG isotype, accomplished through a recombination process involving an intrachromosomal deletion between switch regions that reside 5' of the IgM and one of the IgG constant region gene segments in the immunoglobulin heavy chain locus.	tmpzr1t_l9r_go_relaxed.owl	isotype switch recombination to IgG isotypes|class switching to IgG isotypes													biological_process											owl:Class	
GO:1903750	biolink:NamedThing	regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide	Any process that modulates the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to hydrogen peroxide.	tmpzr1t_l9r_go_relaxed.owl	regulation of intrinsic apoptotic signaling pathway in response to H2O2|regulation of hydrogen peroxide-induced intrinsic apoptotic signaling pathway|regulation of H2O2-induced intrinsic apoptotic signaling pathway|regulation of hydrogen peroxide-induced apoptosis							krc	2014-12-12T23:04:28Z					biological_process											owl:Class	
GO:1900287	biolink:NamedThing	positive regulation of cellotriose transport	Any process that activates or increases the frequency, rate or extent of cellotriose transport.	tmpzr1t_l9r_go_relaxed.owl	activation of cellotriose transport|upregulation of cellotriose transport|up regulation of cellotriose transport|up-regulation of cellotriose transport							tt	2012-04-05T05:57:05Z					biological_process											owl:Class	
GO:1990629	biolink:NamedThing	phospholamban complex	A protein complex found as a homopentamer of the phospholamban (PLN) protein in the sarcoplasmic reticulum (SR) membrane of cardiomyocytes. Cardiac PLN is a main determinant of muscle contraction and relaxation, by regulating intracellular calcium levels.	tmpzr1t_l9r_go_relaxed.owl	cardiac PLN complex|cardiac PLB complex|cardiac phospholamban complex					An example of this is PLN in human (UniProt symbol P26678) in PMID:16043693 (inferred from direct assay).		ame	2015-02-05T14:12:36Z					cellular_component											owl:Class	
GO:0071657	biolink:NamedThing	positive regulation of granulocyte colony-stimulating factor production	Any process that activates or increases the frequency, rate, or extent of production of granulocyte colony-stimulating factor.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of pluripoietin production|positive regulation of granulocyte colony stimulating factor production|positive regulation of colony stimulating factor 3 (granulocyte) production|positive regulation of lenograstim production|positive regulation of G-CSF production|positive regulation of CSF3 production|positive regulation of filgrastim production							mah	2010-02-12T10:41:14Z					biological_process											owl:Class	
GO:0072089	biolink:NamedThing	stem cell proliferation	The multiplication or reproduction of stem cells, resulting in the expansion of a stem cell population. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-02-08T02:03:36Z					biological_process											owl:Class	
GO:0010025	biolink:NamedThing	wax biosynthetic process	The chemical reactions and pathways resulting in the formation of wax, which includes C16 and C18 fatty acids.	tmpzr1t_l9r_go_relaxed.owl	wax anabolism|wax synthesis|wax formation|wax biosynthesis				MetaCyc:PWY-282									biological_process											owl:Class	
GO:1990913	biolink:NamedThing	sperm head plasma membrane	The plasma membrane that is part of the head section of a sperm cell.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-12-07T23:14:04Z					cellular_component											owl:Class	
GO:1903080	biolink:NamedThing	regulation of C-C chemokine receptor CCR7 signaling pathway	Any process that modulates the frequency, rate or extent of C-C chemokine receptor CCR7 signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	regulation of CCR7 signaling pathway|regulation of C-C chemokine receptor CCR7 signalling pathway							rl	2014-05-29T18:32:49Z					biological_process											owl:Class	
GO:0097025	biolink:NamedThing	MPP7-DLG1-LIN7 complex	A heterotrimeric protein complex formed by the association of MMP7, DLG1 and either LIN7A or LIN7C; regulates the stability and localization of DLG1 to cell junctions.	tmpzr1t_l9r_go_relaxed.owl								pr	2011-03-30T05:03:33Z					cellular_component											owl:Class	
GO:0072116	biolink:NamedThing	pronephros formation	The developmental process pertaining to the initial formation of the pronephros. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life.	tmpzr1t_l9r_go_relaxed.owl	pronephric kidney formation							mah	2010-02-22T11:16:26Z					biological_process											owl:Class	
GO:0021705	biolink:NamedThing	locus ceruleus formation	The process that gives rise to the locus ceruleus. This process pertains to the initial formation of a structure from unspecified parts. In mice, the locus ceruleus is a dense cluster of neurons within the dorsorostral pons. This nucleus is the major location of neurons that release norepinephrine throughout the brain, and is responsible for physiological responses to stress and panic.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0009537	biolink:NamedThing	proplastid	The precursor of other plastids.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0070102	biolink:NamedThing	interleukin-6-mediated signaling pathway	A series of molecular signals initiated by the binding of interleukin-6 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.	tmpzr1t_l9r_go_relaxed.owl	IL-6-mediated signaling pathway|interleukin-6-mediated signalling pathway													biological_process											owl:Class	
GO:0071354	biolink:NamedThing	cellular response to interleukin-6	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-6 stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to IL-6							mah	2009-12-11T02:51:14Z					biological_process											owl:Class	
GO:0007199	biolink:NamedThing	G protein-coupled receptor signaling pathway coupled to cGMP nucleotide second messenger	The series of molecular signals generated as a consequence of a G protein-coupled receptor binding to its physiological ligand, followed by activation of guanylyl cyclase (GC) activity and a subsequent increase in the concentration of cyclic GMP (cGMP).	tmpzr1t_l9r_go_relaxed.owl	G-protein signalling, coupled to cGMP nucleotide second messenger|G protein signalling, coupled to cGMP nucleotide second messenger|guanylate cyclase-activating G-protein coupled receptor signaling pathway|G-protein signaling, coupled to cGMP nucleotide second messenger|GPCR signaling pathway via activation of guanylate cyclase activity|G protein signaling, coupled to cGMP nucleotide second messenger|GPCR signaling pathway via cGMP second messenger|G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger													biological_process											owl:Class	
GO:0090629	biolink:NamedThing	lagging strand initiation	The process in which the synthesis of DNA from a template strand in a net 3' to 5' direction is started.	tmpzr1t_l9r_go_relaxed.owl								tb	2015-02-11T14:37:13Z					biological_process											owl:Class	
GO:1904808	biolink:NamedThing	positive regulation of protein oxidation	Any process that activates or increases the frequency, rate or extent of protein oxidation.	tmpzr1t_l9r_go_relaxed.owl	up regulation of protein amino acid oxidation|up regulation of protein oxidation|upregulation of protein oxidation|positive regulation of protein amino acid oxidation|activation of protein oxidation|up-regulation of protein amino acid oxidation|activation of protein amino acid oxidation|upregulation of protein amino acid oxidation|up-regulation of protein oxidation							mec	2015-11-10T14:06:15Z					biological_process											owl:Class	
GO:0030745	biolink:NamedThing	dimethylhistidine N-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + N-alpha,N-alpha-dimethyl-L-histidine = S-adenosyl-L-homocysteine + N-alpha,N-alpha,N-alpha-trimethyl-L-histidine.	tmpzr1t_l9r_go_relaxed.owl	S-adenosyl-L-methionine:Nalpha,Nalpha-dimethyl-L-histidine nalpha-methyltransferase activity|histidine-alpha-N-methyltransferase activity|S-adenosyl-L-methionine:alpha-N,alpha-N-dimethyl-L-histidine alpha-N-methyltransferase activity|dimethylhistidine methyltransferase activity				RHEA:11104|EC:2.1.1.44|MetaCyc:2.1.1.44-RXN|KEGG_REACTION:R04436									molecular_function											owl:Class	
GO:0001552	biolink:NamedThing	ovarian follicle atresia	A periodic process in which immature ovarian follicles degenerate and are subsequently re-absorbed.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0051014	biolink:NamedThing	actin filament severing	The process in which an actin filament is broken down into smaller filaments.	tmpzr1t_l9r_go_relaxed.owl	actin filament severing activity|barbed-end actin capping/severing activity|F-actin severing													biological_process											owl:Class	
GO:0070937	biolink:NamedThing	CRD-mediated mRNA stability complex	A protein complex that binds to, and promotes stabilization of, mRNA molecules containing the coding region instability determinant (CRD). In human, it may consist of IGF2BP1, HNRNPU, SYNCRIP/HNRNPQ, YBX1, and DHX9.	tmpzr1t_l9r_go_relaxed.owl	coding-region determinant of instability-mediated mRNA stability complex|coding-region instability determinant -mediated mRNA stability complex					See also the molecular function term 'alkyl hydroperoxide reductase activity ; GO:0008785'.		mah	2009-09-22T02:00:22Z					cellular_component											owl:Class	
GO:0101027	biolink:NamedThing	optical nerve axon regeneration	The regrowth of axons of the optical nerve following their loss or damage.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0085036	biolink:NamedThing	extrahaustorial matrix	The space between the symbiont plasma membrane and the extrahaustorial membrane of the host.	tmpzr1t_l9r_go_relaxed.owl						See also: haustorium ; GO:0085035 and extrahaustorial membrane ; GO:0085037.		jl	2010-07-27T03:58:20Z					cellular_component											owl:Class	
GO:0043655	biolink:NamedThing	host extracellular space	The space within a host but external to the plasma membrane of host cells, e.g. within host bloodstream.	tmpzr1t_l9r_go_relaxed.owl	extracellular space of host													cellular_component											owl:Class	
GO:0003367	biolink:NamedThing	cell-cell adhesion involved in ameboidal cell migration	The attachment of one ameboid cell to another that contributes to the establishment of cell polarity that is part of the directed movement of one of the cells.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-12-08T05:15:49Z					biological_process											owl:Class	
GO:0003365	biolink:NamedThing	establishment of cell polarity involved in ameboidal cell migration	The specification and formation of anisotropic intracellular organization that contributes to the self-propelled directed movement of an ameboid cell.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-12-08T04:50:41Z					biological_process											owl:Class	
GO:0005723	biolink:NamedThing	alpha-heterochromatin	A small, compact region of heterochromatin located in the middle of the polytene chromosome chromocenter, which undergoes little or no replication during polytenization.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0052706	biolink:NamedThing	histidine N-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + L-histidine = S-adenosyl-L-homocysteine + N-alpha,N-alpha,N-alpha-trimethyl-L-histidine.	tmpzr1t_l9r_go_relaxed.owl	histidine methyltransferase activity|histidine-alpha-N-methyltransferase activity|S-adenosyl-L-methionine:L-histidine Nalpha-methyltransferase activity|S-adenosyl-L-methionine:L-histidine alpha-N-methyltransferase activity							ai	2011-08-05T11:57:40Z					molecular_function											owl:Class	
GO:0031526	biolink:NamedThing	brush border membrane	The portion of the plasma membrane surrounding the brush border.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0005903	biolink:NamedThing	brush border	The dense covering of microvilli on the apical surface of an epithelial cell in tissues such as the intestine, kidney, and choroid plexus; the microvilli aid absorption by increasing the surface area of the cell.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Brush_border									cellular_component											owl:Class	
GO:0048288	biolink:NamedThing	nuclear membrane fusion involved in karyogamy	The joining of 2 or more lipid bilayer membranes that surround the nucleus during the creation of a single nucleus from multiple nuclei.	tmpzr1t_l9r_go_relaxed.owl	nuclear membrane fusion during karyogamy													biological_process											owl:Class	
GO:2001239	biolink:NamedThing	regulation of extrinsic apoptotic signaling pathway in absence of ligand	Any process that modulates the frequency, rate or extent of extrinsic apoptotic signaling pathway in absence of ligand.	tmpzr1t_l9r_go_relaxed.owl	regulation of extrinsic apoptotic signalling pathway in absence of ligand|regulation of extrinsic apoptosis in absence of ligand|regulation of dependence receptor signaling pathway							pr	2011-11-24T01:33:18Z					biological_process											owl:Class	
GO:0030292	biolink:NamedThing	protein tyrosine kinase inhibitor activity	Stops, prevents or reduces the activity of a protein tyrosine kinase.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1990270	biolink:NamedThing	platelet-derived growth factor receptor-ligand complex	A tetrameric protein complex consisting of two platelet-derived growth factor (PDGF) receptor subunits and two PDGF ligand subunits. Binding of the PDGF ligand dimer to the PDGF receptor in the plasma membrane induces receptor dimerisation and activation. PDGFs are involved in a wide variety of signalling processes and are found in all vertebrates. At least two different receptor chains (A and B) and four types of ligand chains (A, B, C, and D) are known forming a wide variety of combinations of receptor-ligand complexes.	tmpzr1t_l9r_go_relaxed.owl	PDGF-CC-receptor alpha complex|PDGF-CC-receptor beta complex|PDGF-AB-receptor alpha complex|PDGF-BB-receptor alpha-beta complex|PDGF-DD-receptor alpha-beta complex|PDGF-AA-receptor alpha complex|PDGF-AB-receptor beta complex|PDGF receptor-ligand complex|PDGF-BB-receptor beta complex|PDGF-BB-receptor alpha complex|PDGF-DD-receptor beta complex|receptor-ligand complex|PDGF-CC-receptor alpha-beta complex|PDGF complex					An example of this is PDGFA-PGFRA in human (UniProt symbols P04085, P16234) in PMID:7679113 (inferred from direct assay).		bhm	2014-01-14T11:12:22Z					cellular_component											owl:Class	
GO:0060855	biolink:NamedThing	venous endothelial cell migration involved in lymph vessel development	The orderly movement of venous endothelial cells out of the veins giving rise to the precursors of lymphatic endothelial cells.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-08-12T12:07:27Z					biological_process											owl:Class	
GO:1902979	biolink:NamedThing	mitotic DNA replication termination	Any DNA replication termination involved in mitotic cell cycle DNA replication.	tmpzr1t_l9r_go_relaxed.owl	DNA replication termination involved in mitotic cell cycle DNA replication							jl	2014-05-06T19:19:49Z					biological_process											owl:Class	
GO:0031145	biolink:NamedThing	anaphase-promoting complex-dependent catabolic process	The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, with ubiquitin-protein ligation catalyzed by the anaphase-promoting complex, and mediated by the proteasome.	tmpzr1t_l9r_go_relaxed.owl	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolism|cyclin catabolism|APC-dependent proteasomal ubiquitin-dependent protein catabolism|anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein degradation|degradation of cyclin|cyclin breakdown|cyclin catabolic process|negative regulation of cyclin-dependent protein serine/threonine kinase by cyclin degradation|anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process|APC-dependent proteasomal ubiquitin-dependent protein catabolic process|cyclin degradation|anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein breakdown											GO:0008054		biological_process											owl:Class	
GO:0060664	biolink:NamedThing	epithelial cell proliferation involved in salivary gland morphogenesis	The multiplication or reproduction of epithelial cells of the submandibular salivary gland, resulting in the expansion of a cell population and the shaping of the gland.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-06-01T08:36:13Z					biological_process											owl:Class	
GO:0003033	biolink:NamedThing	detection of hypoxic conditions in blood by aortic body chemoreceptor signaling	The process in which information about a lack of oxygen are received and are converted to a molecular signal by chemoreceptors in the aortic bodies.	tmpzr1t_l9r_go_relaxed.owl	detection of hypoxic conditions in blood by aortic body chemoreceptor signalling													biological_process											owl:Class	
GO:0002778	biolink:NamedThing	antibacterial peptide production	The synthesis or release of an antibacterial peptide during an immune response, resulting in an increase in intracellular or extracellular levels.	tmpzr1t_l9r_go_relaxed.owl						Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.								biological_process											owl:Class	
GO:0032284	biolink:NamedThing	plastid biotin carboxylase complex	A biotin carboxylase complex located in the stroma of a plastid.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0000914	biolink:NamedThing	phragmoplast assembly	The formation of a structure composed of actin, myosin, and associated proteins that will function in cytokinesis in cells that perform cytokinesis by cell plate formation. The structure usually contains antiparallel microtubules and membrane (often visible as vesicles).	tmpzr1t_l9r_go_relaxed.owl	phragmoplast formation													biological_process											owl:Class	
GO:1905432	biolink:NamedThing	regulation of retrograde trans-synaptic signaling by neuropeptide	Any process that modulates the frequency, rate or extent of retrograde trans-synaptic signaling by neuropeptide.	tmpzr1t_l9r_go_relaxed.owl	regulation of neuropeptide-mediated retrograde trans-synaptic signaling							bf	2016-09-14T10:56:47Z					biological_process											owl:Class	
GO:0071166	biolink:NamedThing	ribonucleoprotein complex localization	Any process in which a ribonucleoprotein complex is transported to, or maintained in, a specific location within a cell.	tmpzr1t_l9r_go_relaxed.owl	establishment and maintenance of ribonucleoprotein complex localization|cellular ribonucleoprotein complex localization|RNP localization|ribonucleoprotein complex localisation							mah	2009-11-19T04:46:05Z					biological_process											owl:Class	
GO:0007496	biolink:NamedThing	anterior midgut development	The process whose specific outcome is the progression of the anterior midgut over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0035253	biolink:NamedThing	ciliary rootlet	A cytoskeleton-like structure, originating from the basal body at the proximal end of a cilium, and extending proximally toward the cell nucleus. Rootlets are typically 80-100 nm in diameter and contain cross striae distributed at regular intervals of approximately 55-70 nm.	tmpzr1t_l9r_go_relaxed.owl	cilium rootlet|cilial rootlet													cellular_component											owl:Class	
GO:0048802	biolink:NamedThing	notum morphogenesis	The process in which the anatomical structures of the dorsal part of the body are generated and organized.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0007472	biolink:NamedThing	wing disc morphogenesis	The process in which the anatomical structures derived from the wing disc are generated and organized. This includes the transformation of a wing imaginal disc from a monolayered epithelium in the larvae of holometabolous insects into recognizable adult structures including the wing hinge, wing blade and pleura.	tmpzr1t_l9r_go_relaxed.owl	wing disc metamorphosis													biological_process											owl:Class	
GO:0000486	biolink:NamedThing	cleavage between 5.8S rRNA and 2S rRNA of tetracistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, 2S rRNA, LSU-rRNA)	Endonucleolytic cleavage between the 5.8S rRNA and the 2S rRNA of an rRNA molecule originally produced as a tetracistronic rRNA transcript that contained the Small SubUnit (SSU) rRNA, the 5.8S rRNA, 2S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0060670	biolink:NamedThing	branching involved in labyrinthine layer morphogenesis	The process in which the branches of the fetal placental villi are generated and organized. The villous part of the placenta is called the labyrinth layer.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-06-02T10:40:40Z					biological_process											owl:Class	
GO:1901664	biolink:NamedThing	regulation of NAD+ ADP-ribosyltransferase activity	Any process that modulates the frequency, rate or extent of NAD+ ADP-ribosyltransferase activity.	tmpzr1t_l9r_go_relaxed.owl	regulation of poly(ADP-ribose)polymerase activity|regulation of poly(adenosine diphosphate ribose) polymerase activity|regulation of ADP-ribosyltransferase (polymerizing) activity|regulation of poly(ADP-ribose) synthase activity|regulation of NAD ADP-ribosyltransferase activity|regulation of NAD+:poly(adenine-diphosphate-D-ribosyl)-acceptor ADP-D-ribosyl-transferase activity|regulation of poly(ADP-ribose) synthetase activity							vk	2012-11-20T18:50:07Z					biological_process											owl:Class	
GO:0003360	biolink:NamedThing	brainstem development	The progression of the brainstem from its formation to the mature structure. The brainstem is the part of the brain that connects the brain with the spinal cord.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-12-03T10:47:20Z					biological_process											owl:Class	
GO:0070575	biolink:NamedThing	peptide mating pheromone maturation involved in regulation of pheromone-induced unidirectional conjugation	The formation of a mature peptide mating pheromone by proteolysis and/or modification of a peptide precursor, occurring in the context of pheromone-induced unidirectional conjugation.	tmpzr1t_l9r_go_relaxed.owl	peptide mating pheromone formation involved in pheromone-induced unidirectional conjugation|peptide mating pheromone processing involved in pheromone-induced unidirectional conjugation							mah	2009-04-20T04:32:07Z					biological_process											owl:Class	
GO:0060242	biolink:NamedThing	contact inhibition	The series of events in which information about the density of cells in a population is received by direct cell-cell contact and is converted into a molecular signal, resulting in the cessation of cell growth or proliferation.	tmpzr1t_l9r_go_relaxed.owl	detection of cell density by contact stimulus|detection of cell density by contact stimulus involved in contact inhibition				Wikipedia:Contact_inhibition							GO:0060248|GO:0060246		biological_process											owl:Class	
GO:1903575	biolink:NamedThing	cornified envelope assembly	The aggregation, arrangement and bonding together of a set of components to form a cornified envelope.	tmpzr1t_l9r_go_relaxed.owl	cornified envelope formation					An example of this is syntaxin 4 in PMID:22226963.		pr	2014-10-28T10:22:49Z					biological_process											owl:Class	
GO:1902982	biolink:NamedThing	DNA strand elongation involved in premeiotic DNA replication	Any DNA strand elongation involved in meiotic cell cycle DNA replication.	tmpzr1t_l9r_go_relaxed.owl	DNA strand elongation involved in meiotic cell cycle DNA replication							jl	2014-05-06T20:33:15Z					biological_process											owl:Class	
GO:0005933	biolink:NamedThing	cellular bud	A protuberance from a cell of an organism that reproduces by budding, which will grow larger and become a separate daughter cell after nuclear division, cytokinesis, and cell wall formation (when appropriate). The daughter cell may completely separate from the mother cell, or the mother and daughter cells may remain associated.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0003393	biolink:NamedThing	neuron migration involved in retrograde extension	The directed, self-propelled movement of a neuron that contributes to the process of retrograde extension.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-12-09T09:36:03Z					biological_process											owl:Class	
GO:0031134	biolink:NamedThing	sister chromatid biorientation	The cell cycle process in which sister chromatids establish stable attachments to microtubules emanating from opposite spindle poles.	tmpzr1t_l9r_go_relaxed.owl	chromosome biorientation|sister kinetochore biorientation													biological_process											owl:Class	
GO:0007274	biolink:NamedThing	neuromuscular synaptic transmission	The process of synaptic transmission from a neuron to a muscle, across a synapse.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0061811	biolink:NamedThing	ADP-ribosyl cyclase activity	Catalysis of the reaction: NAD = cyclic ADP-ribose + nicotinamide.	tmpzr1t_l9r_go_relaxed.owl								dph	2016-11-11T13:25:18Z					molecular_function											owl:Class	
GO:0036186	biolink:NamedThing	early phagosome membrane	The lipid bilayer surrounding an early phagosome.	tmpzr1t_l9r_go_relaxed.owl	early phagocytic vesicle membrane							bf	2012-04-16T02:37:30Z					cellular_component											owl:Class	
GO:0055097	biolink:NamedThing	high density lipoprotein particle mediated signaling	A series of molecular signals mediated by the detection of high density lipoprotein particle.	tmpzr1t_l9r_go_relaxed.owl	high density lipoprotein particle-mediated signaling|high density lipoprotein mediated signalling|high density lipoprotein particle mediated signal transduction													biological_process											owl:Class	
GO:0071403	biolink:NamedThing	cellular response to high density lipoprotein particle stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a high density lipoprotein particle stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to high-density lipoprotein particle stimulus|response to high density lipoprotein particle|response to high density lipoprotein particle stimulus							mah	2009-12-14T02:51:43Z			GO:0055099		biological_process											owl:Class	
GO:0004915	biolink:NamedThing	interleukin-6 receptor activity	Combining with interleukin-6 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	gp130|IL-6 receptor activity|IL-6R													molecular_function											owl:Class	
GO:0036365	biolink:NamedThing	transforming growth factor beta2 activation	The release of transforming growth factor beta 2 (TGF-beta2) from its latent state.	tmpzr1t_l9r_go_relaxed.owl	TGF-beta 2 activation|TGFB2 activation|TGFbeta 2 activation							bf	2012-09-24T10:15:11Z					biological_process											owl:Class	
GO:0010783	biolink:NamedThing	proboscis morphogenesis, eye-antennal disc-derived	The process in which the anatomical structures of the proboscis that are derived from the eye-antennal disc are generated and organized.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0016592	biolink:NamedThing	mediator complex	A protein complex that interacts with the carboxy-terminal domain of the largest subunit of RNA polymerase II and plays an active role in transducing the signal from a transcription factor to the transcriptional machinery. The mediator complex is required for activation of transcription of most protein-coding genes, but can also act as a transcriptional corepressor. The Saccharomyces complex contains several identifiable subcomplexes: a head domain comprising Srb2, -4, and -5, Med6, -8, and -11, and Rox3 proteins; a middle domain comprising Med1, -4, and -7, Nut1 and -2, Cse2, Rgr1, Soh1, and Srb7 proteins; a tail consisting of Gal11p, Med2p, Pgd1p, and Sin4p; and a regulatory subcomplex comprising Ssn2, -3, and -8, and Srb8 proteins. Metazoan mediator complexes have similar modular structures and include homologs of yeast Srb and Med proteins.	tmpzr1t_l9r_go_relaxed.owl	TRAP complex|Srb-mediator complex|L mediator complex|CDK8-containing TRAP/mediator complex				Wikipedia:Mediator_(coactivator)							GO:0000119		cellular_component											owl:Class	
GO:0014818	biolink:NamedThing	skeletal muscle satellite cell fate determination	The process in which a cell becomes capable of differentiating autonomously into a skeletal muscle satellite cell regardless of its environment; upon determination, the cell fate cannot be reversed.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0003047	biolink:NamedThing	regulation of systemic arterial blood pressure by epinephrine	The regulation of blood pressure mediated by the catecholamine signaling molecule epinephrine.	tmpzr1t_l9r_go_relaxed.owl	blood pressure regulation by epinephrine|regulation of blood pressure by adrenaline													biological_process											owl:Class	
GO:0003153	biolink:NamedThing	closure of embryonic heart tube	Creation of the central hole of the embryonic heart tube by sealing the edges of an epithelial fold.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-09-23T10:14:54Z					biological_process											owl:Class	
GO:0007493	biolink:NamedThing	endodermal cell fate determination	The cell fate determination process in which a cell becomes capable of differentiating autonomously into an endoderm cell regardless of its environment; upon determination, the cell fate cannot be reversed.	tmpzr1t_l9r_go_relaxed.owl	endoderm cell fate determination					Note that this term was 'endoderm determination'. Changed string to make it more consistent with parent term 'cell fate determination'.								biological_process											owl:Class	
GO:2000543	biolink:NamedThing	positive regulation of gastrulation	Any process that activates or increases the frequency, rate or extent of gastrulation.	tmpzr1t_l9r_go_relaxed.owl								yaf	2011-04-01T04:10:15Z					biological_process											owl:Class	
GO:0005638	biolink:NamedThing	lamin filament	Any of a group of intermediate-filament proteins that form the fibrous matrix on the inner surface of the nuclear envelope. They are classified as lamins A, B and C.	tmpzr1t_l9r_go_relaxed.owl	type V intermediate filament													cellular_component											owl:Class	
GO:0030540	biolink:NamedThing	female genitalia development	The process whose specific outcome is the progression of the female genitalia over time, from formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl	female genital development													biological_process											owl:Class	
GO:2001109	biolink:NamedThing	regulation of lens epithelial cell proliferation	Any process that modulates the frequency, rate or extent of lens epithelial cell proliferation.	tmpzr1t_l9r_go_relaxed.owl								yaf	2011-09-30T02:04:53Z					biological_process											owl:Class	
GO:1902212	biolink:NamedThing	negative regulation of prolactin signaling pathway	Any process that stops, prevents or reduces the frequency, rate or extent of prolactin signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of prolactin-mediated signaling pathway|inhibition of PRL signaling pathway|down regulation of prolactin signaling pathway|down regulation of PRL signaling pathway|downregulation of prolactin-mediated signaling pathway|inhibition of prolactin-mediated signaling pathway|down regulation of prolactin-mediated signaling pathway|inhibition of prolactin signaling pathway|downregulation of prolactin signaling pathway|downregulation of PRL signaling pathway|down-regulation of PRL signaling pathway|negative regulation of prolactin-mediated signaling pathway|negative regulation of PRL signaling pathway|down-regulation of prolactin signaling pathway							lb	2013-06-12T10:10:12Z					biological_process											owl:Class	
GO:0062120	biolink:NamedThing	LinE complex assembly	The aggregation, arrangement and bonding together of a set of components during meiotic prophase to form a LinE complex, the protein complex that associates with chromatin to form linear elements in fission yeast. In S. pombe, the LinE complex contains four main structural components (Rec10, Rec25, Rec27, and Mug20) and other associated proteins.	tmpzr1t_l9r_go_relaxed.owl								dph	2019-03-19T14:14:25Z					biological_process											owl:Class	
GO:0048226	biolink:NamedThing	Casparian strip	Region of plant cell wall specialised to act as a seal to prevent back leakage of secreted material (analogous to tight junction between epithelial cells). Found particularly where root parenchymal cells secrete solutes into xylem vessels. The barrier is composed of suberin; a fatty substance, containing long chain fatty acids and fatty esters, also found in the cell walls of cork cells (phellem) in higher plants.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Casparian_strip									cellular_component											owl:Class	
GO:0014055	biolink:NamedThing	acetylcholine secretion, neurotransmission	The regulated release of acetylcholine by a cell. The acetylcholine acts as a neurotransmitter that acts in both the peripheral nervous system (PNS) and central nervous system (CNS).	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0035801	biolink:NamedThing	adrenal cortex development	The process whose specific outcome is the progression of the adrenal cortex over time, from its formation to the mature structure. The adrenal cortex is located at the periphery of the adrenal gland and controls glucose and electrolyte metabolism, response to stress and sexual development through the production of different classes of steroid hormones (glucocorticoids, mineralocorticoids and androgens).	tmpzr1t_l9r_go_relaxed.owl	adrenal gland cortex development							bf	2011-04-18T10:25:39Z					biological_process											owl:Class	
GO:0140213	biolink:NamedThing	negative regulation of long-chain fatty acid import into cell	Any process that stops, prevents or reduces the frequency, rate or extent of long-chain fatty acid import into a cell.	tmpzr1t_l9r_go_relaxed.owl								pg	2018-04-10T15:13:28Z					biological_process											owl:Class	
GO:0004705	biolink:NamedThing	JUN kinase activity	Catalysis of the reaction: JUN + ATP = JUN phosphate + ADP. This reaction is the phosphorylation and activation of members of the JUN family, a gene family that encodes nuclear transcription factors.	tmpzr1t_l9r_go_relaxed.owl	c-Jun N-terminal kinase activity|SAPK1|JNK|JNK3alpha1				Reactome:R-HSA-168136|Reactome:R-HSA-205132|Reactome:R-HSA-9673789|Reactome:R-HSA-205075|Reactome:R-HSA-204949									molecular_function											owl:Class	
GO:0046982	biolink:NamedThing	protein heterodimerization activity	Binding to a nonidentical protein to form a heterodimer.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0003305	biolink:NamedThing	cell migration involved in heart jogging	The orderly movement of a cell of the myocardium from one site to another that will contribute to heart jogging.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-10-22T11:05:46Z					biological_process											owl:Class	
GO:0015901	biolink:NamedThing	cycloheximide transport	The directed movement of cycloheximide into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Cycloheximide is an antibiotic produced by Streptomyces which interferes with protein synthesis in eukaryotes.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0035161	biolink:NamedThing	imaginal disc lineage restriction	Formation and/or maintenance of a lineage boundary between compartments in an imaginal disc that cells cannot cross, thus separating the populations of cells in each compartment.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0032584	biolink:NamedThing	growth cone membrane	The portion of the plasma membrane surrounding a growth cone.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0070246	biolink:NamedThing	natural killer cell apoptotic process	Any apoptotic process in a natural killer cell, a lymphocyte that can spontaneously kill a variety of target cells without prior antigenic activation.	tmpzr1t_l9r_go_relaxed.owl	natural killer cell apoptosis|NK cell apoptosis													biological_process											owl:Class	
GO:0032123	biolink:NamedThing	deep fiber	Inward projections of the cytoskeletal structures of the oral apparatus, which form a fiber that extends past the cytostome into the cytoplasm.	tmpzr1t_l9r_go_relaxed.owl	deep fibre													cellular_component											owl:Class	
GO:0031460	biolink:NamedThing	glycine betaine transport	The directed movement of glycine betaine, N-trimethylglycine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	N-trimethylglycine transport													biological_process											owl:Class	
GO:1902066	biolink:NamedThing	regulation of cell wall pectin metabolic process	Any process that modulates the frequency, rate or extent of cell wall pectin metabolic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of plant-type cell wall pectin metabolic process|regulation of pectin metabolism during cell wall biogenesis|regulation of cell wall pectin metabolism|regulation of cellulose and pectin-containing cell wall pectin metabolic process							tb	2013-04-17T20:05:56Z					biological_process											owl:Class	
GO:1903144	biolink:NamedThing	actomyosin contractile ring actin filament	Any actin filament that is part of a actomyosin contractile ring.	tmpzr1t_l9r_go_relaxed.owl	actin filament of CAR|actin filament of actomyosin ring|actin filament of actomyosin contractile ring|actin filament of contractile actomyosin ring|actin filament of cytokinetic ring							vw	2014-07-06T16:20:05Z					cellular_component											owl:Class	
GO:0035344	biolink:NamedThing	hypoxanthine transport	The directed movement of hypoxanthine, 6-hydroxypurine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	6-hydroxypurine transport|hypoxanthine transmembrane transport							bf	2010-03-04T10:39:55Z					biological_process											owl:Class	
GO:0032903	biolink:NamedThing	regulation of nerve growth factor production	Any process that modulates the frequency, rate, or extent of production of nerve growth factor (NGF).	tmpzr1t_l9r_go_relaxed.owl	regulation of NGF production|regulation of beta-nerve growth factor production													biological_process											owl:Class	
GO:0004385	biolink:NamedThing	guanylate kinase activity	Catalysis of the reaction: ATP + GMP = ADP + GDP.	tmpzr1t_l9r_go_relaxed.owl	GMP kinase activity|deoxyguanylate kinase activity|membrane-associated guanylate kinase|ATP:(d)GMP phosphotransferase activity|ATP:GMP phosphotransferase activity|5'-GMP kinase activity|guanosine monophosphate kinase activity				MetaCyc:GUANYL-KIN-RXN|RHEA:20780|Reactome:R-HSA-110133|EC:2.7.4.8|Reactome:R-HSA-73788									molecular_function											owl:Class	
GO:0000743	biolink:NamedThing	nuclear migration involved in conjugation with cellular fusion	The microtubule-based movement of nuclei towards one another as a prelude to karyogamy in organisms undergoing conjugation with cellular fusion.	tmpzr1t_l9r_go_relaxed.owl	nuclear migration during conjugation with cellular fusion|nuclear congression											GO:0006946		biological_process											owl:Class	
GO:1903107	biolink:NamedThing	insulin receptor signaling pathway involved in dauer larval development	Any insulin receptor signaling pathway that is involved in dauer larval development.	tmpzr1t_l9r_go_relaxed.owl	daf-2 receptor signaling pathway involved in dauer larval development|insulin receptor signalling pathway involved in dauer larval development							kmv	2014-06-05T21:30:03Z					biological_process											owl:Class	
GO:1905427	biolink:NamedThing	intracellular signal transduction involved in positive regulation of cell growth	Any intracellular signal transduction that is involved in positive regulation of cell growth.	tmpzr1t_l9r_go_relaxed.owl	intracellular signaling pathway involved in upregulation of cell growth|intracellular protein kinase cascade involved in activation of cell growth|intracellular signal transduction pathway involved in positive regulation of cell growth|protein kinase cascade involved in up-regulation of cell growth|intracellular signaling cascade involved in upregulation of cell growth|intracellular signaling chain involved in up regulation of cell growth|intracellular protein kinase cascade involved in stimulation of cell growth|intracellular signal transduction pathway involved in up-regulation of cell growth|intracellular signaling chain involved in stimulation of cell growth|protein kinase cascade involved in stimulation of cell growth|signal transduction via intracellular signaling cascade involved in positive regulation of cell growth|intracellular signaling pathway involved in positive regulation of cell growth|intracellular signal transduction involved in up regulation of cell growth|intracellular signaling pathway involved in stimulation of cell growth|intracellular signaling chain involved in up-regulation of cell growth|protein kinase cascade involved in activation of cell growth|intracellular protein kinase cascade involved in positive regulation of cell growth|intracellular signal transduction involved in stimulation of cell growth|signal transduction via intracellular signaling cascade involved in up-regulation of cell growth|signal transduction via intracellular signaling cascade involved in activation of cell growth|signal transmission via intracellular cascade involved in activation of cell growth|intracellular protein kinase cascade involved in up-regulation of cell growth|signal transmission via intracellular cascade involved in positive regulation of cell growth|protein kinase cascade involved in positive regulation of cell growth|intracellular signaling pathway involved in up regulation of cell growth|protein kinase cascade involved in up regulation of cell growth|intracellular signal transduction involved in upregulation of cell growth|intracellular signal transduction involved in activation of cell growth|intracellular signaling pathway involved in up-regulation of cell growth|intracellular signaling cascade involved in activation of cell growth|intracellular signaling cascade involved in up regulation of cell growth|intracellular signal transduction pathway involved in upregulation of cell growth|intracellular protein kinase cascade involved in upregulation of cell growth|signal transduction via intracellular signaling cascade involved in up regulation of cell growth|intracellular signaling chain involved in positive regulation of cell growth|signal transmission via intracellular cascade involved in stimulation of cell growth|intracellular signaling chain involved in upregulation of cell growth|intracellular signaling cascade involved in stimulation of cell growth|intracellular signaling pathway involved in activation of cell growth|intracellular signaling cascade involved in up-regulation of cell growth|signal transmission via intracellular cascade involved in upregulation of cell growth|intracellular signaling cascade involved in positive regulation of cell growth|intracellular protein kinase cascade involved in up regulation of cell growth|signal transmission via intracellular cascade involved in up-regulation of cell growth|signal transmission via intracellular cascade involved in up regulation of cell growth|intracellular signal transduction pathway involved in up regulation of cell growth|signal transduction via intracellular signaling cascade involved in upregulation of cell growth|intracellular signaling chain involved in activation of cell growth|intracellular signal transduction involved in up-regulation of cell growth|intracellular signal transduction pathway involved in activation of cell growth|signal transduction via intracellular signaling cascade involved in stimulation of cell growth|protein kinase cascade involved in upregulation of cell growth|intracellular signal transduction pathway involved in stimulation of cell growth							dph	2016-09-07T18:15:01Z					biological_process											owl:Class	
GO:0021722	biolink:NamedThing	superior olivary nucleus maturation	A developmental process, independent of morphogenetic (shape) change, that is required for the superior olivary nucleus to attain its fully functional state. The superior olivary nucleus is a small cylindrical mass on the dorsal surface of the lateral part of the trapezoid body of the pons, and it is situated immediately above the inferior olivary nucleus. It receives projections from the cochlear nucleus and thus is involved in the perception of sound.	tmpzr1t_l9r_go_relaxed.owl	superior olive maturation													biological_process											owl:Class	
GO:0035689	biolink:NamedThing	chemokine (C-C motif) ligand 5 signaling pathway	A series of molecular signals initiated by the binding of the chemokine CCL5 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.	tmpzr1t_l9r_go_relaxed.owl	CCL5-mediated signaling pathway|chemokine (C-C motif) ligand 5 signalling pathway|RANTES-mediated signaling pathway							bf	2011-02-24T12:56:13Z					biological_process											owl:Class	
GO:0021588	biolink:NamedThing	cerebellum formation	The process that gives rise to the cerebellum. This process pertains to the initial formation of a structure from unspecified parts. The cerebellum is the portion of the brain in the back of the head between the cerebrum and the pons. The cerebellum controls balance for walking and standing, modulates the force and range of movement and is involved in the learning of motor skills.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0062242	biolink:NamedThing	double membrane vesicle viral factory membrane	One of the two endoplasmic reticulum-derived lipid bilayer membranes that bound a double membrane vesicle viral factory.	tmpzr1t_l9r_go_relaxed.owl	membrane of double membrane vesicle viral factory							dph	2020-04-20T20:42:28Z					cellular_component											owl:Class	
GO:0035849	biolink:NamedThing	nephric duct elongation	The process in which the nephric duct grows along its axis. A nephric duct is a tube that drains a primitive kidney.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-05-11T11:31:39Z					biological_process											owl:Class	
GO:0061939	biolink:NamedThing	c-di-GMP signaling	Any process that mediates the transfer of information from one cell to another using c-di-GMP as the signal.	tmpzr1t_l9r_go_relaxed.owl	cyclic di-(3':5')-guanosine monophosphate signaling|3',5'-cyclic di-GMP signaling|cyclic diguanylate signaling|cyclic di-GMP signaling							dph	2017-09-14T18:59:04Z					biological_process											owl:Class	
GO:0006824	biolink:NamedThing	cobalt ion transport	The directed movement of cobalt (Co) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	cobalt transport													biological_process											owl:Class	
GO:0072086	biolink:NamedThing	specification of loop of Henle identity	The process in which the loop of Henle of the kidney nephron acquires its identity.	tmpzr1t_l9r_go_relaxed.owl	specification of intermediate tubule identity							mah	2010-02-01T02:49:35Z			GO:0072083		biological_process											owl:Class	
GO:0060506	biolink:NamedThing	smoothened signaling pathway involved in lung development	The series of molecular signals generated as a consequence of activation of the transmembrane Smoothened-type protein. This process contributes to lung development.	tmpzr1t_l9r_go_relaxed.owl	hh signaling pathway involved in lung development|hedgehog signaling pathway involved in lung development|smoothened signalling pathway involved in lung development													biological_process											owl:Class	
GO:0001059	biolink:NamedThing	transcription by RNA polymerase IV	The synthesis of RNA from a DNA template by RNA polymerase IV, originating at a Pol IV-specific promoter.	tmpzr1t_l9r_go_relaxed.owl	transcription from RNA polymerase IV promoter|transcription from RNA pol IV promoter	https://github.com/geneontology/go-ontology/issues/14854						krc	2010-09-23T03:51:35Z					biological_process											owl:Class	
GO:0015761	biolink:NamedThing	mannose transmembrane transport	The process in which mannose is transported across a lipid bilayer, from one side of a membrane to the other. Mannose is the aldohexose manno-hexose, the C-2 epimer of glucose. The D-(+)-form is widely distributed in mannans and hemicelluloses and is of major importance in the core oligosaccharide of N-linked oligosaccharides of glycoproteins.	tmpzr1t_l9r_go_relaxed.owl	mannose transport													biological_process											owl:Class	
GO:0097480	biolink:NamedThing	establishment of synaptic vesicle localization	The directed movement of a synaptic vesicle or vesicles to a specific location.	tmpzr1t_l9r_go_relaxed.owl	establishment of synaptic vesicle localisation							pr	2013-05-22T14:32:12Z					biological_process											owl:Class	
GO:0048823	biolink:NamedThing	nucleate erythrocyte development	The process aimed at the progression of a nucleate erythrocyte over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.	tmpzr1t_l9r_go_relaxed.owl	nucleate RBC development|nucleate red blood cell development													biological_process											owl:Class	
GO:0043363	biolink:NamedThing	nucleate erythrocyte differentiation	The process in which a myeloid precursor cell acquires specializes features of an erythrocyte with a nucleus, as found in non-mammalian vertebrates such as birds.	tmpzr1t_l9r_go_relaxed.owl	nucleate RBC differentiation|nucleate red blood cell differentiation													biological_process											owl:Class	
GO:0060337	biolink:NamedThing	type I interferon signaling pathway	A series of molecular signals initiated by the binding of a type I interferon to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families.	tmpzr1t_l9r_go_relaxed.owl	type I interferon-mediated signaling pathway|type I interferon-activated signaling pathway|type I interferon-mediated signalling pathway													biological_process											owl:Class	
GO:0090139	biolink:NamedThing	mitochondrial DNA packaging	Any process in which mitochondrial DNA and associated proteins are formed into a compact, orderly structure.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-12-08T02:12:19Z					biological_process											owl:Class	
GO:1902263	biolink:NamedThing	apoptotic process involved in embryonic digit morphogenesis	Any apoptotic process that is involved in embryonic digit morphogenesis.	tmpzr1t_l9r_go_relaxed.owl	programmed cell death by apoptosis involved in embryonic digit morphogenesis|type I programmed cell death involved in embryonic digit morphogenesis|apoptotic cell death involved in embryonic digit morphogenesis|signaling (initiator) caspase activity involved in embryonic digit morphogenesis|apoptotic programmed cell death involved in embryonic digit morphogenesis|apoptotic program involved in embryonic digit morphogenesis|apoptosis involved in embryonic digit morphogenesis							dph	2013-06-25T16:19:22Z					biological_process											owl:Class	
GO:0015150	biolink:NamedThing	fucose transmembrane transporter activity	Enables the transfer of fucose from one side of a membrane to the other. Fucose is 6-deoxygalactose and has two enantiomers, D-fucose and L-fucose.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0015756	biolink:NamedThing	fucose transmembrane transport	The process in which fucose is transported across a lipid bilayer, from one side of a membrane to the other. Fucose is 6-deoxygalactose and has two enantiomers, D-fucose and L-fucose.	tmpzr1t_l9r_go_relaxed.owl	fucose transport													biological_process											owl:Class	
GO:0021901	biolink:NamedThing	early neuron fate commitment in forebrain	The commitment of neuroepithelial cell to become a neuron that will reside in the forebrain.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0052616	biolink:NamedThing	ent-kaur-16-en-19-ol oxidase activity	Catalysis of the reaction: H+ + NADPH + ent-kaur-16-en-19-ol + oxygen = 2 H2O + NADP+ + ent-kaur-16-en-19-al.	tmpzr1t_l9r_go_relaxed.owl					RHEA:21304|EC:1.14.14.86|MetaCyc:RXN-5242									molecular_function											owl:Class	
GO:0021687	biolink:NamedThing	cerebellar molecular layer morphogenesis	The process in which the anatomical structure of the cerebellar molecular layer is generated and organized. The molecular layer is the outermost layer of the cerebellar cortex. It contains the parallel fibers of the granule cells, interneurons such as stellate and basket cells, and the dendrites of the underlying Purkinje cells.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0060109	biolink:NamedThing	medial layer of collagen and cuticulin-based cuticle extracellular matrix	The fluid-filled cuticle layer that lies between the cortical and basal layers and is characterized by the presence of regularly spaced columnar struts that lie on either side of the annular furrows and link the two surrounding layers. In C. elegans, a defined medial layer is found only in adult animals.	tmpzr1t_l9r_go_relaxed.owl	medial layer struts													cellular_component											owl:Class	
GO:0015211	biolink:NamedThing	purine nucleoside transmembrane transporter activity	Enables the transfer of a purine nucleoside, a purine base covalently bonded to a ribose or deoxyribose sugar, from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1902980	biolink:NamedThing	synthesis of RNA primer involved in premeiotic DNA replication	Any synthesis of RNA primer involved in meiotic cell cycle DNA replication.	tmpzr1t_l9r_go_relaxed.owl	synthesis of RNA primer involved in meiotic cell cycle DNA replication							jl	2014-05-06T19:19:54Z					biological_process											owl:Class	
GO:0010154	biolink:NamedThing	fruit development	The process whose specific outcome is the progression of the fruit over time, from its formation to the mature structure. The fruit is a reproductive body of a seed plant.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0038176	biolink:NamedThing	positive regulation of SREBP signaling pathway in response to decreased oxygen levels	Any process that activates or increases the frequency, rate or extent of the SREBP signaling pathway in response to a decrease in oxygen levels.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of SREBP-mediated signaling pathway in absence of oxygen|positive regulation of SREBP-mediated signaling pathway in response to decreased oxygen levels							bf	2012-07-20T01:30:25Z					biological_process											owl:Class	
GO:0003228	biolink:NamedThing	atrial cardiac muscle tissue development	The process whose specific outcome is the progression of cardiac muscle of the atrium over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl	atrial myocardium development							dph	2009-10-13T10:53:18Z					biological_process											owl:Class	
GO:0086057	biolink:NamedThing	voltage-gated calcium channel activity involved in bundle of His cell action potential	Enables the transmembrane transfer of a calcium ion by a voltage-gated channel across the plasma membrane of a bundle of His cardiac muscle cell that contributes to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.	tmpzr1t_l9r_go_relaxed.owl	voltage-gated calcium channel activity involved in bundle of His cardiac muscle cell action potential							dph	2011-11-17T12:32:51Z					molecular_function											owl:Class	
GO:0048888	biolink:NamedThing	neuromast mantle cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a neuromast mantle cell. Mantle cells are non-sensory cells that surround the sensory strip, separating the neuromast from the epidermis. Mantle cells secrete the cupula in which the ciliary bundles of all of the hair cells are embedded.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0120120	biolink:NamedThing	bilobe structure	A cytoskeletal structure in some kinetoplastid species linking the structures of the ciliary pocket collar and the flagellum attachment zone (aka cilium attachment zone).	tmpzr1t_l9r_go_relaxed.owl	kinetoplastid flagellar hook complex					Note that we deem cilium and microtubule-based flagellum to be equivalent; the primary term name reflects frequency of use.		krc	2017-12-11T23:47:20Z					cellular_component											owl:Class	
GO:1904228	biolink:NamedThing	positive regulation of glycogen synthase activity, transferring glucose-1-phosphate	Any process that activates or increases the frequency, rate or extent of glycogen synthase activity, transferring glucose-1-phosphate.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of glycogen synthase activity, transferring glucose-1-phosphate|up regulation of glycogen synthase activity, transferring glucose-1-phosphate|upregulation of glycogen synthase activity, transferring glucose-1-phosphate|activation of glycogen synthase activity, transferring glucose-1-phosphate							rl	2015-05-15T09:23:20Z					biological_process											owl:Class	
GO:0045250	biolink:NamedThing	cytosolic pyruvate dehydrogenase complex	Complex that carries out the oxidative decarboxylation of pyruvate to form acetyl-CoA; comprises subunits possessing three catalytic activities: pyruvate dehydrogenase (E1), dihydrolipoamide S-acetyltransferase (E2), and dihydrolipoamide dehydrogenase (E3). Usually contains fewer subunits than its eukaryotic counterpart; for example, the E. coli complex contains 12 E1 dimers, 8 E2 trimers, and 6 E3 dimers arranged in highly symmetric cubic order.	tmpzr1t_l9r_go_relaxed.owl	pyruvate dehydrogenase complex (lipoamide)					Note that this term represents a location and not a function; the activity possessed by this complex is mentioned in the definition for the purpose of describing and distinguishing the complex. The functions of this complex are represented by the molecular function terms 'pyruvate dehydrogenase (lipoamide) activity ; GO:0004739', 'dihydrolipoamide S-acetyltransferase activity ; GO:0004742', and 'dihydrolipoamide dehydrogenase activity ; GO:0004148'.								cellular_component											owl:Class	
GO:0014704	biolink:NamedThing	intercalated disc	A complex cell-cell junction at which myofibrils terminate in cardiomyocytes; mediates mechanical and electrochemical integration between individual cardiomyocytes. The intercalated disc contains regions of tight mechanical attachment (fasciae adherentes and desmosomes) and electrical coupling (gap junctions) between adjacent cells.	tmpzr1t_l9r_go_relaxed.owl	intercalated disk				Wikipedia:Intercalated_disc									cellular_component											owl:Class	
GO:0015719	biolink:NamedThing	allantoate transport	The directed movement of allantoate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	allantoin/allantoate transport													biological_process											owl:Class	
GO:1901026	biolink:NamedThing	ripoptosome assembly involved in necroptotic process	The aggregation, arrangement and bonding together of ripoptosome components leading to a necroptotic process.	tmpzr1t_l9r_go_relaxed.owl	ripoptosome assembly involved in necroptosis							pr	2012-06-19T08:54:28Z					biological_process											owl:Class	
GO:0033118	biolink:NamedThing	esterosome membrane	The lipid bilayer surrounding an esterosome. This membrane has characteristics of rough endoplasmic reticulum (RER) membranes.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0033117	biolink:NamedThing	esterosome	A vesicle filled with crystalline protein that shows sequence similarities with various esterases.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0061303	biolink:NamedThing	cornea development in camera-type eye	The progression of the cornea over time, from its formation to the mature structure. The cornea is the transparent structure that covers the anterior of the eye.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-09-14T02:09:08Z					biological_process											owl:Class	
GO:0045451	biolink:NamedThing	pole plasm oskar mRNA localization	Any process in which oskar mRNA is transported to, or maintained in, the oocyte pole plasm.	tmpzr1t_l9r_go_relaxed.owl	establishment and maintenance of pole plasm oskar mRNA localization|oocyte pole plasm oskar mRNA localization|pole plasm oskar mRNA localisation|establishment and maintenance of oskar mRNA localization in pole plasm													biological_process											owl:Class	
GO:0015689	biolink:NamedThing	molybdate ion transport	The directed movement of molybdate (MoO4 2-) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Molybdate is the bivalent anion derived from molybdic acid.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0042813	biolink:NamedThing	Wnt-activated receptor activity	Combining with a Wnt protein and transmitting the signal across the plasma membrane to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	Wnt receptor activity|frizzled receptor activity|frizzled-2 receptor activity													molecular_function											owl:Class	
GO:0009553	biolink:NamedThing	embryo sac development	The process whose specific outcome is the progression of the embryo sac over time, from its formation to the mature structure. The process begins with the meiosis of the megasporocyte to form four haploid megaspores. Three of the megaspores disintegrate, and the fourth undergoes mitosis giving rise to a binucleate syncytial embryo sac. The two haploid nuclei migrate to the opposite poles of the embryo sac and then undergo two rounds of mitosis generating four haploid nuclei at each pole. One nucleus from each set of four migrates to the center of the cell. Cellularization occurs, resulting in an eight-nucleate seven-celled structure. This structure contains two synergid cells and an egg cell at the micropylar end, and three antipodal cells at the other end. A binucleate endosperm mother cell is formed at the center. The two polar nuclei fuse resulting in a mononucleate diploid endosperm mother cell. The three antipodal cells degenerate.	tmpzr1t_l9r_go_relaxed.owl	female gametophyte development											GO:0048230		biological_process											owl:Class	
GO:0055040	biolink:NamedThing	periplasmic flagellum	Flagellar filaments located in the periplasmic space; characterized in spirochetes, in which they are essential for shape and motility. Composed of a core surrounded by two sheath layers, the flagella rotate to allow migration of the cell through viscous media, which would not be possible using external flagella.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0034089	biolink:NamedThing	establishment of meiotic sister chromatid cohesion	The process in which the sister chromatids of a replicated chromosome become joined along the entire length of the chromosome during S phase during a meiotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0048837	biolink:NamedThing	sorocarp sorus development	The process whose specific outcome is the progression of the sorocarp sorus over time, from its formation to the mature structure.  A sorocarp sorus is the spore containing structure of a sorocarp.	tmpzr1t_l9r_go_relaxed.owl	sorocarp spore head morphogenesis|sorocarp sorus formation|sorocarp spore head formation													biological_process											owl:Class	
GO:0021668	biolink:NamedThing	rhombomere 6 structural organization	The process that contributes to creating the structural organization of rhombomere 6. This process pertains to the physical shaping of a rudimentary structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.	tmpzr1t_l9r_go_relaxed.owl	rhombomere 6 structural organisation													biological_process											owl:Class	
GO:0032678	biolink:NamedThing	regulation of interleukin-9 production	Any process that modulates the frequency, rate, or extent of interleukin-9 production.	tmpzr1t_l9r_go_relaxed.owl	regulation of interleukin-9 biosynthetic process|regulation of IL-9 production											GO:0045417		biological_process											owl:Class	
GO:0048887	biolink:NamedThing	cupula development	The process whose specific outcome is the progression of the cupula over time, from its formation to the mature structure. The cupula is secreted by mantle cells and the ciliary bundles of all of the hair cells of the neuromast are embedded in it. The cupula provides a mechanical linkage between the hair cells and the external hydrodynamic environment. The cupula of superficial neuromasts grows continuously, while the height of the cupula of canal neuromasts is limited by canal diameter.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1904298	biolink:NamedThing	regulation of transcytosis	Any process that modulates the frequency, rate or extent of transcytosis.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-06-09T22:53:26Z					biological_process											owl:Class	
GO:0043056	biolink:NamedThing	forward locomotion	Anterior movement of an organism, following the direction of the head of the animal.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0009539	biolink:NamedThing	photosystem II reaction center	An integral membrane complex containing P680, the chlorophyll a molecule that functions as a primary electron donor. In the light, functioning as a water-plastoquinone oxidoreductase, it transfers electrons from water to plastoquinone.	tmpzr1t_l9r_go_relaxed.owl	photosystem II reaction centre													cellular_component											owl:Class	
GO:0048383	biolink:NamedThing	mesectoderm development	The process whose specific outcome is the progression of the mesectoderm over time, from its formation to the mature structure. In animal embryos, mesectoderm development processes give rise to both mesoderm and ectoderm tissues.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1990244	biolink:NamedThing	histone kinase activity (H2A-T120 specific)	Catalysis of the transfer of a phosphate group to the threonine-120 residue of histone H2A.	tmpzr1t_l9r_go_relaxed.owl	histone threonine kinase activity (H2A-T120 specific)							sp	2013-12-04T06:38:32Z					molecular_function											owl:Class	
GO:0044183	biolink:NamedThing	protein folding chaperone	Binding to a protein or a protein-containing complex to assist the protein folding process.	tmpzr1t_l9r_go_relaxed.owl	protein binding involved in protein folding|chaperone activity				Reactome:R-HSA-9018785			jl	2009-09-25T11:33:48Z					molecular_function											owl:Class	
GO:0051082	biolink:NamedThing	unfolded protein binding	Binding to an unfolded protein.	tmpzr1t_l9r_go_relaxed.owl	chaperone activity	https://github.com/geneontology/go-ontology/issues/21436			Reactome:R-HSA-9694337|Reactome:R-HSA-9683772									molecular_function											owl:Class	
GO:0043505	biolink:NamedThing	CENP-A containing nucleosome	A form of nucleosome located only at the centromere, in which the histone H3 is replaced by the variant form CENP-A (sometimes known as CenH3).	tmpzr1t_l9r_go_relaxed.owl	CENP-S-T-W-X|CenH3 containing nucleosome|centromere specific nucleosome|centromere-specific nucleosome|centromeric nucleosome|CNP-T-W-S-X complex													cellular_component											owl:Class	
GO:0035574	biolink:NamedThing	histone H4-K20 demethylation	The modification of histone H4 by the removal of a methyl group from lysine at position 20 of the histone.	tmpzr1t_l9r_go_relaxed.owl								bf	2010-08-13T10:50:06Z					biological_process											owl:Class	
GO:0030539	biolink:NamedThing	male genitalia development	The process whose specific outcome is the progression of the male genitalia over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl	male genital development													biological_process											owl:Class	
GO:0061300	biolink:NamedThing	cerebellum vasculature development	The process whose specific outcome is the progression of the vasculature of the cerebellum over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-09-06T03:36:40Z					biological_process											owl:Class	
GO:0021971	biolink:NamedThing	corticospinal neuron axon guidance through the medullary pyramid	The process in which the migration of an axon growth cone of a pyramidal cell that is part of the corticospinal tract is directed after exiting the basilar pons through the medullary pyramid in response to a combination of attractive and repulsive cues.	tmpzr1t_l9r_go_relaxed.owl	corticospinal neuron axon pathfinding through the medullary pyramid													biological_process											owl:Class	
GO:0060324	biolink:NamedThing	face development	The biological process whose specific outcome is the progression of a face from an initial condition to its mature state. The face is the ventral division of the head.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0044327	biolink:NamedThing	dendritic spine head	Distal part of the dendritic spine, that carries the post-synaptic density.	tmpzr1t_l9r_go_relaxed.owl	spine head				NIF_Subcellular:sao952643730			jl	2010-08-18T02:33:12Z					cellular_component											owl:Class	
GO:1901490	biolink:NamedThing	regulation of lymphangiogenesis	Any process that modulates the frequency, rate or extent of lymphangiogenesis.	tmpzr1t_l9r_go_relaxed.owl	regulation of lymph vessel formation							dph	2012-10-15T13:08:17Z					biological_process											owl:Class	
GO:0033985	biolink:NamedThing	acidocalcisome lumen	The volume enclosed by the membranes of an acidocalcisome.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0071139	biolink:NamedThing	resolution of recombination intermediates	The cleavage and rejoining of intermediates, such as Holliday junctions, formed during DNA recombination to produce two intact molecules in which genetic material has been exchanged.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-11-16T12:02:21Z					biological_process											owl:Class	
GO:0072032	biolink:NamedThing	proximal convoluted tubule segment 2 development	The process whose specific outcome is the progression of the S2 portion of the proximal convoluted tubule over time, from its formation to the mature structure. The S2 portion of the tubule is involved in reabsorption of water and sodium chloride.	tmpzr1t_l9r_go_relaxed.owl	S2 development							mah	2010-01-25T02:56:36Z					biological_process											owl:Class	
GO:0060091	biolink:NamedThing	kinocilium	A nonmotile primary cilium that is found at the apical surface of auditory receptor cells. The kinocilium is surrounded by actin-based stereocilia.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Kinocilium									cellular_component											owl:Class	
GO:0140399	biolink:NamedThing	aflatoxin B synthase activity	Catalyzes the reaction: 8-O-methylsterigmatocystin + 2 [reduced NADPH--hemoprotein reductase] + 2 O(2) <=> aflatoxin B + 2 [oxidized NADPH--hemoprotein reductase] + H(2)O + methanol + CO(2). Produces both aflatoxin B(1) and aflatoxin B(2).	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-9497|EC:1.14.14.117|MetaCyc:RXN-9502|RHEA:35759			pg	2019-11-29T11:06:07Z					molecular_function											owl:Class	
GO:0043054	biolink:NamedThing	dauer exit	Exit from the facultative diapause of the dauer (enduring) larval stage of nematode development.	tmpzr1t_l9r_go_relaxed.owl	exit from nematode dormancy													biological_process											owl:Class	
GO:0009353	biolink:NamedThing	mitochondrial oxoglutarate dehydrogenase complex	A complex of multiple copies of three enzymatic components: oxoglutarate dehydrogenase (lipoamide) ; EC:1.2.4.2 (E1), dihydrolipoamide S-succinyltransferase ; EC:2.3.1.61 (E2) and dihydrolipoamide dehydrogenase ; EC:1.8.1.4 (E3); catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and carbon dioxide (CO2) within the mitochondrial matrix. An example of this complex is found in Mus musculus.	tmpzr1t_l9r_go_relaxed.owl						See also the molecular functions term 'oxoglutarate dehydrogenase (succinyl-transferring) activity ; GO:0004591', 'dihydrolipoyllysine-residue succinyltransferase activity ; GO:0004149' and 'dihydrolipoyl dehydrogenase activity ; GO:0004148'.								cellular_component											owl:Class	
GO:0072359	biolink:NamedThing	circulatory system development	The process whose specific outcome is the progression of the circulatory system over time, from its formation to the mature structure. The circulatory system is the organ system that passes nutrients (such as amino acids and electrolytes), gases, hormones, blood cells, etc. to and from cells in the body to help fight diseases and help stabilize body temperature and pH to maintain homeostasis.	tmpzr1t_l9r_go_relaxed.owl	cardiovascular system development							mah	2010-11-16T11:27:39Z			GO:0072358		biological_process											owl:Class	
GO:0000328	biolink:NamedThing	fungal-type vacuole lumen	The volume enclosed within the vacuolar membrane of a vacuole, the shape of which correlates with cell cycle phase. An example of this structure is found in Saccharomyces cerevisiae.	tmpzr1t_l9r_go_relaxed.owl	lumen of vacuole with cell cycle-correlated morphology													cellular_component											owl:Class	
GO:0002144	biolink:NamedThing	cytosolic tRNA wobble base thiouridylase complex	A complex of two proteins involved in the thiolation of uridine 34 (U34) of tRNAs decoding two-family box triplets.	tmpzr1t_l9r_go_relaxed.owl	tRNA thiouridylase|Cut1-Cut2 complex							hjd	2009-05-08T02:32:55Z					cellular_component											owl:Class	
GO:0070867	biolink:NamedThing	mating projection tip membrane	The portion of the plasma membrane surrounding a mating projection tip.	tmpzr1t_l9r_go_relaxed.owl	mating projection membrane fusion domain|shmoo tip membrane							mah	2009-08-19T04:05:58Z					cellular_component											owl:Class	
GO:0008035	biolink:NamedThing	high-density lipoprotein particle binding	Binding to high-density lipoprotein particle, a lipoprotein particle with a high density (typically 1.063-1.21 g/ml) and a diameter of 5-10 nm that contains APOAs and may contain APOCs and APOE.	tmpzr1t_l9r_go_relaxed.owl	HDL binding													molecular_function											owl:Class	
GO:0034154	biolink:NamedThing	toll-like receptor 7 signaling pathway	Any series of molecular signals generated as a consequence of binding to toll-like receptor 7.	tmpzr1t_l9r_go_relaxed.owl	TLR7 signaling pathway|toll-like receptor 7 signalling pathway													biological_process											owl:Class	
GO:0035893	biolink:NamedThing	negative regulation of platelet aggregation in other organism	Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of platelet aggregation in a second organism.	tmpzr1t_l9r_go_relaxed.owl	inhibition of platelet aggregation in other organism|suppression of platelet aggregation in other organism|downregulation of platelet aggregation in other organism|down-regulation of platelet aggregation in other organism							bf	2011-06-15T02:24:43Z					biological_process											owl:Class	
GO:0098004	biolink:NamedThing	virus tail fiber assembly	The aggregation, arrangement and bonding together of a set of components to form a virus tail fiber.	tmpzr1t_l9r_go_relaxed.owl								bm	2012-07-18T16:08:15Z					biological_process											owl:Class	
GO:0098003	biolink:NamedThing	viral tail assembly	The aggregation, arrangement and bonding together of a set of components to form a virus tail.	tmpzr1t_l9r_go_relaxed.owl	bacteriophage tail assembly|virus tail assembly							bm	2012-07-18T16:01:59Z					biological_process											owl:Class	
GO:1904039	biolink:NamedThing	negative regulation of iron export across plasma membrane	Any process that stops, prevents or reduces the frequency, rate or extent of export of iron ions from inside of a cell, across the plasma membrane and into the extracellular region.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of ferrous iron export|down-regulation of iron(2+) export|down regulation of iron(2+) export|downregulation of iron(2+) export|downregulation of ferrous iron export|negative regulation of iron(2+) export|down regulation of ferrous iron export|inhibition of ferrous iron export|down-regulation of ferrous iron export|inhibition of iron(2+) export							kom	2015-03-16T15:36:43Z					biological_process											owl:Class	
GO:0033095	biolink:NamedThing	aleurone grain	A membrane-bounded storage granule found in cells of the aleurone layer in plants; contains either a protein matrix, protein-carbohydrate bodies and/or globoids. Aleurone grains are formed by the vacuole, rough endoplasmic reticulum and dictyosomes.	tmpzr1t_l9r_go_relaxed.owl	aleurone body													cellular_component											owl:Class	
GO:0034435	biolink:NamedThing	cholesterol esterification	A lipid modification process in which a sterol ester is formed by the combination of a carboxylic acid (often a fatty acid) and cholesterol. In the blood this process is associated with the conversion of free cholesterol into cholesteryl ester, which is then sequestered into the core of a lipoprotein particle.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0003887	biolink:NamedThing	DNA-directed DNA polymerase activity	Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1); the synthesis of DNA from deoxyribonucleotide triphosphates in the presence of a DNA template and a 3'hydroxyl group.	tmpzr1t_l9r_go_relaxed.owl	DNA duplicase activity|Klenow fragment|Tca DNA polymerase|epsilon DNA polymerase activity|DNA polymerase gamma|kappa DNA polymerase activity|lambda DNA polymerase activity|nu DNA polymerase activity|zeta DNA polymerase activity|alpha DNA polymerase activity|beta DNA polymerase activity|DNA nucleotidyltransferase (DNA-directed) activity|mu DNA polymerase activity|theta DNA polymerase activity|deoxyribonucleic duplicase activity|DNA polymerase V activity|DNA polymerase I|DNA-dependent DNA polymerase activity|DNA polymerase alpha|DNA polymerase II|deoxyribonucleic polymerase I|duplicase|DNA replicase activity|DNA polymerase beta|delta DNA polymerase activity|Taq DNA polymerase|sigma DNA polymerase activity|deoxyribonucleic acid duplicase activity|iota DNA polymerase activity|sequenase|deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (DNA-directed) activity|eta DNA polymerase activity|gamma DNA-directed DNA polymerase activity|DNA polymerase III|Taq Pol I				Reactome:R-HSA-5655892|Reactome:R-HSA-68950|Reactome:R-HSA-5358579|Reactome:R-HSA-110368|Reactome:R-HSA-5649883|Reactome:R-HSA-5656148|Reactome:R-HSA-110311|Reactome:R-HSA-6782208|Reactome:R-HSA-5649723|Reactome:R-HSA-111253|Reactome:R-HSA-6786166|Reactome:R-HSA-174444|MetaCyc:DNA-DIRECTED-DNA-POLYMERASE-RXN|Reactome:R-HSA-5656158|Reactome:R-HSA-5687360|Reactome:R-HSA-5653840|Reactome:R-HSA-69116|Reactome:R-HSA-164505|EC:2.7.7.7|Reactome:R-HSA-5693593|Reactome:R-HSA-164513|Reactome:R-HSA-73932|Reactome:R-HSA-5655965|Reactome:R-HSA-5687640|Reactome:R-HSA-5691001|Reactome:R-HSA-110317|Reactome:R-HSA-174427|Reactome:R-HSA-110319							GO:0016449|GO:0016451|GO:0003888|GO:0003895|GO:0003893|GO:0016452|GO:0003894|GO:0016448|GO:0008723|GO:0003890|GO:0016000|GO:0019984|GO:0003889|GO:0015999|GO:0016450|GO:0003891		molecular_function											owl:Class	
GO:1900001	biolink:NamedThing	negative regulation of anthocyanin catabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of anthocyanin catabolic process.	tmpzr1t_l9r_go_relaxed.owl	down regulation of anthocyanin catabolic process|down regulation of anthocyanin degradation|negative regulation of anthocyanin breakdown|negative regulation of anthocyanin degradation|down regulation of anthocyanin catabolism|negative regulation of anthocyanin catabolism|down regulation of anthocyanin breakdown							tb	2011-12-20T07:12:11Z					biological_process											owl:Class	
GO:0099542	biolink:NamedThing	trans-synaptic signaling by endocannabinoid	Cell-cell signaling in either direction across the synaptic cleft, mediated by an endocannabinoid ligand.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0009515	biolink:NamedThing	granal stacked thylakoid	Appressed thylakoid membranes that are part of a granum (stacked regions). A characteristic of these appressed regions is the preferential localization of photosystem II.	tmpzr1t_l9r_go_relaxed.owl	chloroplast stacked thylakoid													cellular_component											owl:Class	
GO:0009542	biolink:NamedThing	granum	Distinct stack of lamellae seen within chloroplasts. Grana contain the pigments, electron transfer compounds, and enzymes essential to the light-dependent reactions of photosynthesis.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0070147	biolink:NamedThing	mitochondrial cysteinyl-tRNA aminoacylation	The process of coupling cysteine to cysteinyl-tRNA in a mitochondrion, catalyzed by cysteinyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0000138	biolink:NamedThing	Golgi trans cisterna	The Golgi cisterna farthest from the endoplasmic reticulum; the final processing compartment through which proteins pass before exiting the Golgi apparatus; the compartment in which N-linked protein glycosylation is completed.	tmpzr1t_l9r_go_relaxed.owl	late Golgi													cellular_component											owl:Class	
GO:0046790	biolink:NamedThing	virion binding	Binding to a virion, either by binding to components of the capsid or the viral envelope.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0120317	biolink:NamedThing	sperm mitochondrial sheath assembly	The assembly and organization of the sperm mitochondrial sheath, the tightly packed helical sheath of ATP-producing mitochondria restricted to the midpiece of the sperm flagellum.	tmpzr1t_l9r_go_relaxed.owl								krc	2021-04-29T01:52:38Z					biological_process											owl:Class	
GO:0075303	biolink:NamedThing	positive regulation of basidiospore formation	Any process that activates, maintains or increases the frequency, rate or extent of frequency, rate or extent of basidiospore formation, a process in which a sexually produced fungal spore is formed on a basidium in the fungi basidiomycetes.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0006856	biolink:NamedThing	eye pigment precursor transport	The directed movement of eye pigment precursors, the inactive forms of visual pigments, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0004505	biolink:NamedThing	phenylalanine 4-monooxygenase activity	Catalysis of the reaction: L-phenylalanine + tetrahydrobiopterin + O2 = L-tyrosine + 4-alpha-hydroxytetrahydrobiopterin.	tmpzr1t_l9r_go_relaxed.owl	phenylalaninase activity|phenylalanine hydroxylase activity|PAH activity|L-phenylalanine,tetrahydrobiopterin:oxygen oxidoreductase (4-hydroxylating)|phenylalanine 4-hydroxylase activity	https://github.com/geneontology/go-ontology/issues/20583			EC:1.14.16.1|MetaCyc:PHENYLALANINE-4-MONOOXYGENASE-RXN|RHEA:20273|Reactome:R-HSA-71118|Reactome:R-HSA-5649483									molecular_function											owl:Class	
GO:0019293	biolink:NamedThing	tyrosine biosynthetic process, by oxidation of phenylalanine	The conversion of phenylalanine to tyrosine.	tmpzr1t_l9r_go_relaxed.owl	tyrosine synthesis, by oxidation of phenylalanine|tyrosine anabolism, by oxidation of phenylalanine|L-tyrosine biosynthesis IV|tyrosine formation, by oxidation of phenylalanine	https://github.com/geneontology/go-ontology/issues/20583			MetaCyc:PWY-6134							GO:0019291		biological_process											owl:Class	
GO:0098755	biolink:NamedThing	maintenance of seed dormancy by absisic acid	The process by which seed dormancy is maintained by the presence of absisic acid.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0035281	biolink:NamedThing	pre-miRNA export from nucleus	Transport of pre-microRNAs (pre-miRNAs) from the nucleus to the cytoplasm. Pre-miRNAs are a ~60-70 nucleotide stem loop intermediate in miRNA production, produced by the nuclear cleavage of a primary miRNA (pri-mRNA) transcript. Pre-miRNAs are transported from the nucleus to the cytoplasm where further cleavage occurs to produce a mature miRNA product.	tmpzr1t_l9r_go_relaxed.owl	pre-microRNA export out of nucleus|pre-microRNA export from nucleus|pre-microRNA transport from nucleus to cytoplasm|pre-microRNA export from cell nucleus|pre-microRNA-nucleus export	https://github.com/geneontology/go-ontology/issues/22245												biological_process											owl:Class	
GO:0044793	biolink:NamedThing	negative regulation by host of viral process	A process in which a host organism stops, prevents or reduces the frequency, rate or extent of a process being mediated by a virus with which it is infected.	tmpzr1t_l9r_go_relaxed.owl								jl	2013-06-06T11:16:00Z					biological_process											owl:Class	
GO:0021721	biolink:NamedThing	superior olivary nucleus structural organization	The process that contributes to the act of creating the structural organization of the superior olivary nucleus structure. In mice, the superior olivary nucleus is a small cylindrical mass on the dorsal surface of the lateral part of the trapezoid body of the pons, and it is situated immediately above the inferior olivary nucleus. It receives projections from the cochlear nucleus and thus is involved in the perception of sound.	tmpzr1t_l9r_go_relaxed.owl	superior olivary nucleus structural organisation													biological_process											owl:Class	
GO:0099546	biolink:NamedThing	protein catabolic process, modulating synaptic transmission	Any protein degradation process, occurring at a presynapse, that regulates synaptic transmission.	tmpzr1t_l9r_go_relaxed.owl						Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.								biological_process											owl:Class	
GO:0060318	biolink:NamedThing	definitive erythrocyte differentiation	Erythrocyte differentiation which occurs as part of the process of definitive hemopoiesis.	tmpzr1t_l9r_go_relaxed.owl	definitive RBC differentiation|definitive erythropoiesis|definitive red blood cell differentiation													biological_process											owl:Class	
GO:0060916	biolink:NamedThing	mesenchymal cell proliferation involved in lung development	The multiplication or reproduction of cells, resulting in the expansion of a mesenchymal cell population that contributes to the progression of the lung over time. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-09-18T11:50:17Z					biological_process											owl:Class	
GO:0006924	biolink:NamedThing	activation-induced cell death of T cells	A T cell apoptotic process that occurs towards the end of the expansion phase following the initial activation of mature T cells by antigen and is triggered by T cell receptor stimulation and signals transmitted via various surface-expressed members of the TNF receptor family such as Fas ligand, Fas, and TNF and the p55 and p75 TNF receptors.	tmpzr1t_l9r_go_relaxed.owl	AICD|antigen-driven apoptosis|activated T cell apoptosis|activation-induced cell death of T lymphocytes|activation-induced cell death of T-lymphocytes|activation-induced cell death of T-cells													biological_process											owl:Class	
GO:1905061	biolink:NamedThing	negative regulation of cardioblast proliferation	Any process that stops, prevents or reduces the frequency, rate or extent of cardioblast proliferation.	tmpzr1t_l9r_go_relaxed.owl	downregulation of cardioblast proliferation|down-regulation of cardioblast proliferation|inhibition of cardioblast proliferation|down regulation of cardioblast proliferation							bc	2016-03-21T11:00:13Z					biological_process											owl:Class	
GO:0015214	biolink:NamedThing	pyrimidine nucleoside transmembrane transporter activity	Enables the transfer of a pyrimidine nucleoside, a pyrimidine base covalently bonded to a ribose or deoxyribose sugar from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0097575	biolink:NamedThing	lateral cell cortex	The region directly beneath the plasma membrane of the lateral portion of the cell.	tmpzr1t_l9r_go_relaxed.owl								pr	2014-02-26T13:29:22Z					cellular_component											owl:Class	
GO:1904199	biolink:NamedThing	positive regulation of regulation of vascular associated smooth muscle cell membrane depolarization	Any process that activates or increases the frequency, rate or extent of regulation of vascular smooth muscle cell membrane depolarization.	tmpzr1t_l9r_go_relaxed.owl	up regulation of regulation of vascular smooth muscle cell membrane depolarization|upregulation of regulation of vascular smooth muscle cell membrane depolarization|positive regulation of regulation of vascular smooth muscle cell membrane depolarization|up-regulation of regulation of vascular smooth muscle cell membrane depolarization|activation of regulation of vascular smooth muscle cell membrane depolarization							sl	2015-05-07T17:16:50Z					biological_process											owl:Class	
GO:0048726	biolink:NamedThing	labrum development	The process whose specific outcome is the progression of the labrum over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1901067	biolink:NamedThing	ferulate catabolic process	The chemical reactions and pathways resulting in the breakdown of ferulate.	tmpzr1t_l9r_go_relaxed.owl	ferulate catabolism|ferulate degradation|ferulate breakdown							tt	2012-06-29T08:06:37Z					biological_process											owl:Class	
GO:0016495	biolink:NamedThing	C-X3-C chemokine receptor activity	Combining with a C-X3-C chemokine and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. A C-X3-C chemokine has three amino acids between the first two cysteines of the characteristic four-cysteine motif.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0019960	biolink:NamedThing	C-X3-C chemokine binding	Binding to a C-X3-C chemokine; C-X3-C chemokines have three amino acids between the first two cysteines of the characteristic four-cysteine motif.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0016515	biolink:NamedThing	interleukin-13 receptor activity	Combining with interleukin-13 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	IL-13R|IL-13 receptor activity													molecular_function											owl:Class	
GO:0047666	biolink:NamedThing	ammonia kinase activity	Catalysis of the reaction: ATP + NH(4)(+) = ADP + 3 H(+) + phosphoramidate.	tmpzr1t_l9r_go_relaxed.owl	phosphoramidate-adenosine diphosphate phosphotransferase activity|ATP:ammonia phosphotransferase activity|phosphoramidate-ADP-phosphotransferase activity				MetaCyc:AMMONIA-KINASE-RXN|RHEA:11024|KEGG_REACTION:R00141|EC:2.7.3.8									molecular_function											owl:Class	
GO:0102803	biolink:NamedThing	thebane O-demethylase activity	Catalysis of the reaction: thebaine + 2-oxoglutarate + O2 <=> oripavine + formaldehyde + succinate + carbon dioxide.	tmpzr1t_l9r_go_relaxed.owl					EC:1.14.11.32|MetaCyc:RXN-8149									molecular_function											owl:Class	
GO:0034889	biolink:NamedThing	endosulfan hemisulfate sulfatase activity	Catalysis of the reaction: endosulfan hemisulfate + H2O = endosulfan monoalcohol + 2 H+ + sulfate.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r1384									molecular_function											owl:Class	
GO:0004343	biolink:NamedThing	glucosamine 6-phosphate N-acetyltransferase activity	Catalysis of the reaction: D-glucosamine 6-phosphate + acetyl-CoA = N-acetyl-D-glucosamine 6-phosphate + CoA + H(+).	tmpzr1t_l9r_go_relaxed.owl	phosphoglucosamine N-acetylase activity|glucosamine-6-phosphate acetylase activity|acetyl-CoA:D-glucosamine-6-phosphate N-acetyltransferase activity|glucosamine-phosphate N-acetyltransferase activity|N-acetylglucosamine-6-phosphate synthase activity|aminodeoxyglucosephosphate acetyltransferase activity|glucosamine 6-phosphate acetylase activity|phosphoglucosamine transacetylase activity|phosphoglucosamine acetylase activity|D-glucosamine-6-P N-acetyltransferase activity				KEGG_REACTION:R02058|RHEA:10292|MetaCyc:GLUCOSAMINEPNACETYLTRANS-RXN|EC:2.3.1.4|Reactome:R-HSA-449734									molecular_function											owl:Class	
GO:0019150	biolink:NamedThing	D-ribulokinase activity	Catalysis of the reaction: ATP + D-ribulose = ADP + D-ribulose 5-phosphate.	tmpzr1t_l9r_go_relaxed.owl	D-ribulokinase (phosphorylating)|ATP:D-ribulose 5-phosphotransferase activity				EC:2.7.1.47|RHEA:17601|MetaCyc:D-RIBULOKIN-RXN									molecular_function											owl:Class	
GO:0080066	biolink:NamedThing	3-methylthiopropyl-desulfoglucosinolate sulfotransferase activity	Catalysis of the reaction: 3-methylthiopropyl-desulfoglucosinolate + 3'-phosphoadenosine 5'-phosphosulfate = 3-methylthiopropyl-glucosinolate + adenosine 3',5'-bisphosphate.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-2209			dhl	2009-04-13T04:04:08Z					molecular_function											owl:Class	
GO:0102813	biolink:NamedThing	UDP-D-glucose:cyanidin 3-(p-coumaroyl)-glucoside 5-O-glucosyltransferase activity	Catalysis of the reaction: UDP-alpha-D-glucose + cyanidin 3-(p-coumaroyl)-glucoside = shisonin + UDP + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-8205									molecular_function											owl:Class	
GO:0033417	biolink:NamedThing	CUU codon-amino acid adaptor activity	A triplet codon-amino acid adaptor activity that recognizes a CUU codon.	tmpzr1t_l9r_go_relaxed.owl	CTT codon-amino acid adaptor activity|leucine tRNA					Note that in the standard genetic code, CTT codes for leucine.								molecular_function											owl:Class	
GO:0005137	biolink:NamedThing	interleukin-5 receptor binding	Binding to an interleukin-5 receptor.	tmpzr1t_l9r_go_relaxed.owl	interleukin-5 receptor ligand|IL-5													molecular_function											owl:Class	
GO:0031211	biolink:NamedThing	endoplasmic reticulum palmitoyltransferase complex	A complex of the endoplasmic reticulum that catalyzes S-palmitoylation, the addition of palmitate (C16:0) or other long-chain fatty acids to proteins at a cysteine residue.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:1905961	biolink:NamedThing	protein-cysteine S-palmitoyltransferase complex	A protein complex which is capable of protein-cysteine S-palmitoyltransferase activity.	tmpzr1t_l9r_go_relaxed.owl	Palmitoyltransferase ERF2-SHR5 complex|Palmitoyltransferase ERF2/SHR5 complex					An example of this is ERF2 in Saccharomyces cerevisiae (Q06551) in PMID:20851885 (inferred from direct assay)		bhm	2017-02-23T13:33:15Z					cellular_component											owl:Class	
GO:0046230	biolink:NamedThing	2-aminobenzenesulfonate catabolic process	The chemical reactions and pathways resulting in the breakdown of 2-aminobenzenesulfonate, an aromatic sulfonate used in organic synthesis and in the manufacture of various dyes and medicines.	tmpzr1t_l9r_go_relaxed.owl	2-aminobenzenesulphonate catabolic process|2-aminobenzenesulfonate degradation|2-aminobenzenesulfonate breakdown|2-aminobenzenesulfonate catabolism|2-aminobenzenesulphonate catabolism													biological_process											owl:Class	
GO:0031255	biolink:NamedThing	lateral part of motile cell	The area of a motile cell perpendicular to the direction of movement.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0034186	biolink:NamedThing	apolipoprotein A-I binding	Binding to apolipoprotein A-I.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1903285	biolink:NamedThing	positive regulation of hydrogen peroxide catabolic process	Any process that activates or increases the frequency, rate or extent of hydrogen peroxide catabolic process.	tmpzr1t_l9r_go_relaxed.owl	activation of detoxification of H2O2|positive regulation of H2O2 catabolic process|up regulation of detoxification of H2O2|up regulation of hydrogen peroxide catabolic process|activation of hydrogen peroxide removal|positive regulation of detoxification of hydrogen peroxide|positive regulation of hydrogen peroxide breakdown|upregulation of hydrogen peroxide degradation|up regulation of hydrogen peroxide degradation|positive regulation of hydrogen peroxide scavenging|activation of H2O2 catabolic process|up regulation of hydrogen peroxide breakdown|activation of hydrogen peroxide scavenging|up regulation of detoxification of hydrogen peroxide|activation of H2O2 scavenging|up-regulation of detoxification of H2O2|positive regulation of detoxification of H2O2|up-regulation of hydrogen peroxide catabolic process|activation of hydrogen peroxide breakdown|up-regulation of hydrogen peroxide breakdown|upregulation of hydrogen peroxide breakdown|up-regulation of hydrogen peroxide catabolism|up-regulation of detoxification of hydrogen peroxide|up-regulation of hydrogen peroxide removal|upregulation of hydrogen peroxide catabolic process|up regulation of hydrogen peroxide removal|up regulation of hydrogen peroxide scavenging|activation of hydrogen peroxide degradation|activation of hydrogen peroxide catabolism|up-regulation of H2O2 scavenging|upregulation of H2O2 catabolic process|upregulation of hydrogen peroxide catabolism|up-regulation of H2O2 catabolic process|up regulation of H2O2 scavenging|up regulation of hydrogen peroxide catabolism|upregulation of hydrogen peroxide removal|up-regulation of hydrogen peroxide degradation|positive regulation of hydrogen peroxide degradation|positive regulation of hydrogen peroxide catabolism|activation of detoxification of hydrogen peroxide|positive regulation of H2O2 scavenging|up-regulation of hydrogen peroxide scavenging|upregulation of hydrogen peroxide scavenging|activation of hydrogen peroxide catabolic process|upregulation of detoxification of H2O2|positive regulation of hydrogen peroxide removal|upregulation of detoxification of hydrogen peroxide|upregulation of H2O2 scavenging|up regulation of H2O2 catabolic process							bf	2014-08-11T13:28:40Z					biological_process											owl:Class	
GO:0102362	biolink:NamedThing	esculetin 3-O-glucosyltransferase activity	Catalysis of the reaction: esculetin + UDP-alpha-D-glucose <=> 3-O-beta-D-glucosyl-esculetin + UDP + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-13472									molecular_function											owl:Class	
GO:0016199	biolink:NamedThing	axon midline choice point recognition	The recognition of molecules at the central nervous system midline choice point by an axon growth cone; this choice point determines whether the growth cone will cross the midline.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0015944	biolink:NamedThing	formate oxidation	The chemical reactions and pathways by which formate is converted to CO2.	tmpzr1t_l9r_go_relaxed.owl	formic acid oxidation				MetaCyc:PWY-1881									biological_process											owl:Class	
GO:0004130	biolink:NamedThing	cytochrome-c peroxidase activity	Catalysis of the reaction: 2 ferrocytochrome c + hydrogen peroxide = 2 ferricytochrome c + 2 H2O.	tmpzr1t_l9r_go_relaxed.owl	cytochrome c-551 peroxidase activity|cytochrome c peroxidase activity|ferrocytochrome-c:hydrogen-peroxide oxidoreductase activity|cytochrome peroxidase activity|mesocytochrome c peroxidase cyanide|cytochrome c-H2O oxidoreductase activity|apocytochrome c peroxidase activity|mesocytochrome c peroxidase cyanate|mesocytochrome c peroxidase azide				EC:1.11.1.5|MetaCyc:CYTOCHROME-C-PEROXIDASE-RXN|RHEA:16581									molecular_function											owl:Class	
GO:0050280	biolink:NamedThing	sequoyitol dehydrogenase activity	Catalysis of the reaction: 1D-5-O-methyl-myo-inositol + NAD(+) = 2D-5-O-methyl-2,3,5/4,6-pentahydroxycyclohexanone + H(+) + NADH.	tmpzr1t_l9r_go_relaxed.owl	5-O-methyl-myo-inositol:NAD+ oxidoreductase activity				RHEA:11300|MetaCyc:SEQUOYITOL-DEHYDROGENASE-RXN|KEGG_REACTION:R03497|EC:1.1.1.143									molecular_function											owl:Class	
GO:0102389	biolink:NamedThing	polyprenol reductase activity	Catalysis of the reaction: NADP + a ditrans,polycis-dolichol = NADPH + H+ + a di-trans, poly-cis-polyprenol.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-13604|RHEA:34279|EC:1.3.1.94									molecular_function											owl:Class	
GO:0097598	biolink:NamedThing	sperm cytoplasmic droplet	A small amount of cytoplasm surrounded by a cell membrane that is generally retained in spermatozoa after spermiogenesis, when the majority of the cytoplasm is phagocytosed by Sertoli cells to produce what are called residual bodies. Initially, the droplet is located at the neck just behind the head of an elongated spermatid. During epididymal transit, the cytoplasmic droplet migrates caudally to the annulus at the end of the midpiece; the exact position and time varies by species. The cytoplasmic droplet consists of lipids, lipoproteins, RNAs, a variety of hydrolytic enzymes, receptors, ion channels, and Golgi-derived vesicles. The droplet may be involved in regulatory volume loss (RVD) at ejaculation, and in most species, though not in humans, the cytoplasmic droplet is lost at ejaculation. Note that the cytoplasmic droplet is distinct from 'excessive residual cytoplasm' that sometimes remains in epididymal spermatozoa, particularly when spermiogenesis has been disrupted.	tmpzr1t_l9r_go_relaxed.owl	sperm residual cytoplasm							pr	2014-04-10T14:03:30Z					cellular_component											owl:Class	
GO:0071070	biolink:NamedThing	alpha4-beta1 integrin-thrombospondin-2 complex	A protein complex that consists of an alpha4-beta1 integrin complex bound to thrombospondin-2.	tmpzr1t_l9r_go_relaxed.owl	ITGA4-ITGB1-THBS2 complex							mah	2009-11-03T04:05:56Z					cellular_component											owl:Class	
GO:0017014	biolink:NamedThing	protein nitrosylation	The covalent addition of a nitric oxide group to an amino acid within a protein.	tmpzr1t_l9r_go_relaxed.owl	protein amino acid nitrosylation													biological_process											owl:Class	
GO:0060364	biolink:NamedThing	frontal suture morphogenesis	The process in which the frontal suture is generated and organized.	tmpzr1t_l9r_go_relaxed.owl	interfrontal suture morphogenesis													biological_process											owl:Class	
GO:0098569	biolink:NamedThing	internal side of mycolate outer membrane	The side of the mycolate outer membrane that faces the cell wall peptidoglycan. It is rich in long-chain mycolic acids (hydroxylated branched-chain fatty acids) that are covalently linked to the cell wall peptidoglycan via an arabinogalactan network.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0007601	biolink:NamedThing	visual perception	The series of events required for an organism to receive a visual stimulus, convert it to a molecular signal, and recognize and characterize the signal. Visual stimuli are detected in the form of photons and are processed to form an image.	tmpzr1t_l9r_go_relaxed.owl	vision|sense of sight|sensory visual perception				Wikipedia:Visual_perception									biological_process											owl:Class	
GO:0080184	biolink:NamedThing	response to phenylpropanoid	Any process that results in a change in state or activity of a cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as the result of a phenylpropanoid stimulus. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism. A phenylpropanoid is any of secondary metabolites with structures based on a phenylpropane skeleton. The class includes phenylpropanoid esters, flavonoids, anthocyanins, coumarins and many small phenolic molecules. Phenylpropanoids are also precursors of lignin.	tmpzr1t_l9r_go_relaxed.owl								dhl	2011-08-10T04:28:21Z					biological_process											owl:Class	
GO:0035088	biolink:NamedThing	establishment or maintenance of apical/basal cell polarity	Any cellular process that results in the specification, formation or maintenance polarization of a cell's architecture along its apical/basal axis so that the apical and basal regions of the cell have different membrane, extracellular matrix and sub-membrane cellular components.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0061761	biolink:NamedThing	alpha-latrotoxin receptor binding	Binding to an alpha-latrotoxin receptor.	tmpzr1t_l9r_go_relaxed.owl	latrophilin binding|lasso receptor binding							dph	2016-04-13T10:46:42Z					molecular_function											owl:Class	
GO:0071416	biolink:NamedThing	cellular response to tropane	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tropane stimulus. Tropane is a nitrogenous bicyclic organic compound mainly known for a group of alkaloids derived from it (called tropane alkaloids), which include, among others, atropine and cocaine.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-12-14T03:12:24Z					biological_process											owl:Class	
GO:0002155	biolink:NamedThing	regulation of thyroid hormone mediated signaling pathway	Any process that modulates the frequency, rate or extent of a thyroid hormone mediated signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	regulation of thyroid hormone mediated signalling pathway							hjd	2009-11-19T12:37:46Z					biological_process											owl:Class	
GO:1990203	biolink:NamedThing	MdtBC Complex	A protein complex containing two transmembrane subunits; a MdtB dimer and one unit of MdtC. Capable of exporting substrates across the cell membrane. Involved in conferring antibiotic resistance of Gram-negative bacteria by transporting drugs across the membrane.	tmpzr1t_l9r_go_relaxed.owl	multidrug efflux pump MdtBC							bhm	2013-10-04T21:22:18Z					cellular_component											owl:Class	
GO:0047378	biolink:NamedThing	acetylalkylglycerol acetylhydrolase activity	Catalysis of the reaction: 2-acetyl-1-alkyl-sn-glycerol + H(2)O = 1-alkyl-sn-glycerol + acetate + H(+).	tmpzr1t_l9r_go_relaxed.owl	alkylacetylglycerol acetylhydrolase activity|2-acetyl-1-alkyl-sn-glycerol acetylhydrolase activity				EC:3.1.1.71|KEGG_REACTION:R04043|RHEA:11552|MetaCyc:3.1.1.71-RXN									molecular_function											owl:Class	
GO:0099069	biolink:NamedThing	synaptic vesicle tethering involved in synaptic vesicle exocytosis	The initial, indirect interaction between a synaptic vesicle membrane and a the preseynaptic membrane active zone. This interaction is mediated by tethering factors (or complexes), which interact with both membranes. This process is distinct from and prior to synaptic vesicle priming and fusion.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0019133	biolink:NamedThing	choline monooxygenase activity	Catalysis of the reaction: choline + 2 reduced ferredoxin + O2 + 2 H+ = betaine aldehyde hydrate + 2 oxidized ferredoxin + H2O.	tmpzr1t_l9r_go_relaxed.owl	choline,reduced-ferredoxin:oxygen oxidoreductase activity				RHEA:17769|MetaCyc:RXN1F-357|EC:1.14.15.7									molecular_function											owl:Class	
GO:0072168	biolink:NamedThing	specification of anterior mesonephric tubule identity	The process in which the tubules of the anterior mesonephros acquire their identity.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-02-26T01:52:36Z					biological_process											owl:Class	
GO:0034068	biolink:NamedThing	aminoglycoside nucleotidyltransferase activity	Catalysis of the reaction: nucleoside triphosphate + aminoglycoside = diphosphate + nucleotidylaminoglycoside.	tmpzr1t_l9r_go_relaxed.owl	aminoglycoside adenylyltransferase activity|streptomycin-spectinomycin adenylyltransferase activity|streptomycin adenylate synthetase activity|streptomycin adenylyltransferase activity|streptomycin adenyltransferase activity|streptomycin adenylylase activity													molecular_function											owl:Class	
GO:0039685	biolink:NamedThing	rolling hairpin viral DNA replication	A viral DNA replication process where a 3' hairpin structure in the viral single-stranded DNA (ssDNA) template serves as a primer for host enzymes to synthesize DNA.	tmpzr1t_l9r_go_relaxed.owl	ssDNA rolling hairpin viral DNA replication				VZ:2656			bf	2013-10-17T14:33:55Z					biological_process											owl:Class	
GO:0050700	biolink:NamedThing	CARD domain binding	Binding to a CARD (N-terminal caspase recruitment) domain, a protein-protein interaction domain that belongs to the death domain-fold superfamily. These protein molecule families are similar in structure with each consisting of six or seven anti-parallel alpha-helices that form highly specific homophilic interactions between signaling partners. CARD exists in the N-terminal prodomains of several caspases and in apoptosis-regulatory proteins and mediates the assembly of CARD-containing proteins that participate in activation or suppression of CARD carrying members of the caspase family.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0102679	biolink:NamedThing	(5alpha)-campestan-3-one hydroxylase activity	Catalysis of the reaction: H+ + (5alpha)-campestan-3-one + O2 + NADPH <=> (5alpha,22S,24R)-22-hydroxyergostan-3-one + H2O + NADP.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-4230									molecular_function											owl:Class	
GO:0071055	biolink:NamedThing	alpha9-beta1 integrin-ADAM9 complex	A protein complex that consists of an alpha9-beta1 integrin complex bound to the transmembrane metallopeptidase ADAM9.	tmpzr1t_l9r_go_relaxed.owl	ITGA9-ITGB1-ADAM9 complex							mah	2009-11-03T03:59:24Z					cellular_component											owl:Class	
GO:1903193	biolink:NamedThing	sesquarterpene biosynthetic process	The chemical reactions and pathways resulting in the formation of sesquarterpene.	tmpzr1t_l9r_go_relaxed.owl	sesquarterpene formation|sesquarterpene synthesis|sesquarterpene anabolism|sesquarterpene biosynthesis							tt	2014-07-16T17:04:53Z					biological_process											owl:Class	
GO:0008217	biolink:NamedThing	regulation of blood pressure	Any process that modulates the force with which blood travels through the circulatory system. The process is controlled by a balance of processes that increase pressure and decrease pressure.	tmpzr1t_l9r_go_relaxed.owl	control of blood pressure|blood pressure regulation|blood pressure homeostasis				Wikipedia:Blood_pressure#Regulation									biological_process											owl:Class	
GO:0102123	biolink:NamedThing	gibberellin A4 16alpha,17 epoxidase activity	Catalysis of the reaction: gibberellin A4 + O2 + H+ + NAD(P)H <=> 16alpha,17-epoxy gibberellin A4 + H2O + NAD(P).	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-11385									molecular_function											owl:Class	
GO:0018813	biolink:NamedThing	trans-o-hydroxybenzylidenepyruvate hydratase-aldolase activity	Catalysis of the reaction: 2-oxo-3-enoate-4-benzenoid + H2O = pyruvate + benzaldehyde derivative. Substrates are (3E)-4-(5-amino-2-hydroxy-phenyl)-2-oxo-but-3-ene-1-oic-acid (forms 5-aminosalicylaldehyde) and trans-o-hydroxybenzylidenepyruvate (forms salicylaldehyde).	tmpzr1t_l9r_go_relaxed.owl					EC:4.1.2.45|RHEA:27389|UM-BBD_enzymeID:e0257									molecular_function											owl:Class	
GO:1903713	biolink:NamedThing	asparagine transmembrane transport	The directed movement of asparagine across a membrane.	tmpzr1t_l9r_go_relaxed.owl								vw	2014-12-06T08:17:55Z					biological_process											owl:Class	
GO:0050018	biolink:NamedThing	L-amino-acid dehydrogenase activity	Catalysis of the reaction: an L-amino acid + H2O + NAD+ = a 2-oxo acid + NH3 + NADH.	tmpzr1t_l9r_go_relaxed.owl	L-amino-acid:NAD+ oxidoreductase (deaminating)				MetaCyc:L-AMINO-ACID-DEHYDROGENASE-RXN|EC:1.4.1.5|RHEA:10396									molecular_function											owl:Class	
GO:0071890	biolink:NamedThing	bicarbonate binding	Binding to bicarbonate ions (CHO3-).	tmpzr1t_l9r_go_relaxed.owl	hydrogencarbonate binding|CHO3- ion binding binding							mah	2010-09-14T01:47:43Z					molecular_function											owl:Class	
GO:0047347	biolink:NamedThing	aldose-1-phosphate nucleotidyltransferase activity	Catalysis of the reaction: aldose 1-phosphate + NDP = phosphate + NDP-aldose.	tmpzr1t_l9r_go_relaxed.owl	NDP:aldose-1-phosphate nucleotidyltransferase activity|nucleoside diphosphosugar phosphorylase activity|glucose 1-phosphate inosityltransferase activity|sugar phosphate nucleotidyltransferase activity|sugar-1-phosphate nucleotidyltransferase activity|sugar nucleotide phosphorylase activity|NDPaldose phosphorylase activity|nucleoside diphosphate sugar:orthophosphate nucleotidyltransferase activity|NDP:alpha-D-aldose-1-phosphate nucleotidyltransferase activity|NDP sugar phosphorylase activity|NDP-aldose phosphorylase activity|NDP-sugar phosphorylase activity				EC:2.7.7.37|MetaCyc:2.7.7.37-RXN									molecular_function											owl:Class	
GO:0140339	biolink:NamedThing	phosphatidylglycerol transfer activity	Directly binding to phosphatidylglycerol and delivering it either to an acceptor molecule or to a specific location.	tmpzr1t_l9r_go_relaxed.owl	phosphatidylglycerol carrier activity							pg	2019-05-16T11:34:45Z					molecular_function											owl:Class	
GO:1905810	biolink:NamedThing	regulation of excitatory synapse pruning	Any process that modulates the frequency, rate or extent of excitatory synapse pruning.	tmpzr1t_l9r_go_relaxed.owl	regulation of synapse clearance|regulation of synapse removal|regulation of synapse elimination|regulation of synapse disassembly							tb	2017-01-12T02:38:27Z					biological_process											owl:Class	
GO:1905806	biolink:NamedThing	regulation of synapse pruning	Any process that modulates the frequency, rate or extent of synapse pruning.	tmpzr1t_l9r_go_relaxed.owl	regulation of synapse clearance|regulation of synapse elimination|regulation of synapse removal|regulation of synapse disassembly							tb	2017-01-11T22:03:15Z					biological_process											owl:Class	
GO:1904225	biolink:NamedThing	positive regulation of glucuronosyltransferase activity	Any process that activates or increases the frequency, rate or extent of glucuronosyltransferase activity.	tmpzr1t_l9r_go_relaxed.owl	activation of 1-naphthol-UDP-glucuronosyltransferase activity|activation of bilirubin uridine diphosphoglucuronyltransferase activity|activation of UDPGA transferase activity|positive regulation of UDP-glucuronate-bilirubin glucuronyltransferase activity|activation of estrone UDPglucuronosyltransferase activity|positive regulation of uridine diphosphoglucuronate-estriol 16alpha-glucuronosyltransferase activity|activation of UDP glucuronate-estriol glucuronosyltransferase activity|upregulation of uridine diphosphoglucuronyltransferase activity|activation of 4-nitrophenol UDP-glucuronyltransferase activity|up regulation of UDP glucuronate-estradiol-glucuronosyltransferase activity|positive regulation of bilirubin uridine diphosphoglucuronyltransferase activity|up regulation of estrone UDPglucuronosyltransferase activity|upregulation of uridine diphosphoglucuronate-estriol 16-alpha-glucuronosyltransferase activity|upregulation of estriol UDPglucuronosyltransferase activity|upregulation of UDPGT activity|up regulation of UDP glucuronyltransferase activity|up-regulation of PNP-UDPGT|upregulation of uridine diphosphoglucuronate-bilirubin glucuronoside glucuronosyltransferase activity|up regulation of pnp-UDPGT activity|upregulation of PNP-UDPGT|activation of UDPGT activity|up regulation of uridine diphosphoglucuronate-estriol 16alpha-glucuronosyltransferase activity|up regulation of UDPGA-glucuronyltransferase activity|up regulation of uridine diphosphoglucuronate-bilirubin glucuronosyltransferase activity|activation of UDP-glucuronate beta-D-glucuronosyltransferase (acceptor-unspecific)|up regulation of p-hydroxybiphenyl UDP glucuronyltransferase activity|up regulation of 17-OH steroid UDPGT activity|activation of p-phenylphenol glucuronyltransferase activity|up regulation of UDP glucuronosyltransferase activity|up-regulation of uridine diphosphoglucuronyltransferase activity|activation of uridine diphosphoglucuronate-1,2-diacylglycerol glucuronosyltransferase activity|upregulation of uridine diphosphoglucuronate-4-hydroxybiphenyl glucuronosyltransferase activity|positive regulation of 3alpha-hydroxysteroid UDP-glucuronosyltransferase activity|activation of UDP glucuronic acid transferase activity|positive regulation of 3-alpha-hydroxysteroid UDP-glucuronosyltransferase activity|up regulation of 17-beta-hydroxysteroid UDP-glucuronosyltransferase activity|up-regulation of uridine diphosphoglucuronate-estriol glucuronosyltransferase activity|up regulation of p-nitrophenylglucuronosyltransferase activity|up regulation of phenyl-UDP-glucuronosyltransferase activity|positive regulation of UDPGT activity|upregulation of uridine diphosphoglucuronate-bilirubin glucuronosyltransferase activity|up-regulation of p-nitrophenol UDP-glucuronyltransferase activity|up-regulation of bilirubin glucuronyltransferase activity|up regulation of 3-OH androgenic UDPGT activity|positive regulation of p-nitrophenol UDP-glucuronosyltransferase activity|up regulation of uridine diphosphate glucuronyltransferase activity|up regulation of uridine diphosphoglucuronyltransferase activity|upregulation of UDP glucuronosyltransferase activity|up-regulation of uridine 5'-diphosphoglucuronyltransferase activity|positive regulation of uridine 5'-diphosphoglucuronyltransferase activity|upregulation of uridine diphosphoglucuronate-estriol 16alpha-glucuronosyltransferase activity|up-regulation of p-nitrophenylglucuronosyltransferase activity|up-regulation of 3-OH androgenic UDPGT activity|activation of ciramadol UDP-glucuronyltransferase activity|upregulation of bilirubin UDP-glucuronosyltransferase activity|up regulation of uridine diphosphoglucuronate-estradiol glucuronosyltransferase activity|activation of UDPglucuronate beta-D-glucuronosyltransferase (acceptor-unspecific) activity|up-regulation of UDP glucuronate-estriol glucuronosyltransferase activity|positive regulation of uridine diphosphoglucuronate-bilirubin glucuronosyltransferase activity|activation of uridine diphosphoglucuronate-estriol 16alpha-glucuronosyltransferase activity|upregulation of 3-alpha-hydroxysteroid UDP-glucuronosyltransferase activity|up regulation of p-nitrophenol UDP-glucuronosyltransferase activity|up regulation of bilirubin UDPGT activity|up regulation of UDP-glucuronyltransferase activity|upregulation of p-phenylphenol glucuronyltransferase activity|activation of uridine diphosphoglucuronate-estriol glucuronosyltransferase activity|positive regulation of 4-nitrophenol UDP-glucuronyltransferase activity|up-regulation of UDP-glucuronate-bilirubin glucuronyltransferase activity|upregulation of UDPGA-glucuronyltransferase activity|upregulation of UDP-glucuronate-4-hydroxybiphenyl glucuronosyltransferase activity|positive regulation of UDP glucuronate-estriol glucuronosyltransferase activity|up-regulation of p-hydroxybiphenyl UDP glucuronyltransferase activity|activation of 17-beta-hydroxysteroid UDP-glucuronosyltransferase activity|upregulation of 17-beta-hydroxysteroid UDP-glucuronosyltransferase activity|upregulation of UDP-glucuronate beta-D-glucuronosyltransferase (acceptor-unspecific)|upregulation of 4-nitrophenol UDPGT activity|up-regulation of GT activity|positive regulation of p-nitrophenol UDP-glucuronyltransferase activity|up-regulation of UDP-glucuronosyltransferase activity|activation of uridine diphosphoglucuronate-estriol 16-alpha-glucuronosyltransferase activity|up-regulation of UDPGA transferase activity|positive regulation of estriol UDPglucuronosyltransferase activity|upregulation of uridine diphosphoglucuronate-estriol glucuronosyltransferase activity|activation of UDP-glucuronate-4-hydroxybiphenyl glucuronosyltransferase activity|up-regulation of UDP-glucuronyltransferase activity|positive regulation of uridine diphosphoglucuronate-estradiol glucuronosyltransferase activity|positive regulation of UDP-glucuronate beta-D-glucuronosyltransferase (acceptor-unspecific)|up-regulation of 3-alpha-hydroxysteroid UDP-glucuronosyltransferase activity|activation of uridine diphosphoglucuronyltransferase activity|up-regulation of bilirubin uridine diphosphoglucuronyltransferase activity|up-regulation of 17-OH steroid UDPGT activity|up-regulation of 4-methylumbelliferone UDP-glucuronosyltransferase activity|activation of 17-OH steroid UDPGT activity|activation of bilirubin UDP-glucuronosyltransferase activity|up regulation of 4-nitrophenol UDPGT activity|upregulation of bilirubin glucuronyltransferase activity|activation of uridine diphosphoglucuronate-4-hydroxybiphenyl glucuronosyltransferase activity|up-regulation of UDPGT activity|activation of 4-hydroxybiphenyl UDP-glucuronosyltransferase activity|up regulation of 3alpha-hydroxysteroid UDP-glucuronosyltransferase activity|positive regulation of 3-OH androgenic UDPGT activity|up regulation of bilirubin monoglucuronide glucuronyltransferase activity|positive regulation of ciramadol UDP-glucuronyltransferase activity|positive regulation of 17-beta-hydroxysteroid UDP-glucuronosyltransferase activity|positive regulation of p-nitrophenylglucuronosyltransferase activity|activation of bilirubin UDPGT activity|up-regulation of UDP-glucuronate beta-D-glucuronosyltransferase (acceptor-unspecific)|up regulation of UDPGT activity|up-regulation of uridine diphosphoglucuronate-1,2-diacylglycerol glucuronosyltransferase activity|up-regulation of UDP glucuronosyltransferase activity|activation of UDPGA-glucuronyltransferase activity|activation of estriol UDPglucuronosyltransferase activity|upregulation of phenyl-UDP-glucuronosyltransferase activity|up-regulation of uridine diphosphoglucuronate-estriol 16alpha-glucuronosyltransferase activity|up regulation of uridine diphosphoglucuronate-estriol glucuronosyltransferase activity|upregulation of uridine diphosphoglucuronosyltransferase activity|up-regulation of 1-naphthol glucuronyltransferase activity|positive regulation of bilirubin UDP-glucuronosyltransferase activity|upregulation of p-nitrophenylglucuronosyltransferase activity|positive regulation of bilirubin glucuronyltransferase activity|activation of 4-methylumbelliferone UDP-glucuronosyltransferase activity|activation of uridine diphosphoglucuronate-bilirubin glucuronoside glucuronosyltransferase activity|up regulation of 1-naphthol-UDP-glucuronosyltransferase activity|activation of uridine diphosphate glucuronyltransferase activity|activation of UDP glucuronosyltransferase activity|up regulation of p-nitrophenol UDP-glucuronyltransferase activity|up-regulation of bilirubin monoglucuronide glucuronyltransferase activity|positive regulation of pnp-UDPGT activity|activation of 3-alpha-hydroxysteroid UDP-glucuronosyltransferase activity|upregulation of 4-methylumbelliferone UDP-glucuronosyltransferase activity|up regulation of uridine 5'-diphosphoglucuronyltransferase activity|up-regulation of uridine diphosphate glucuronyltransferase activity|upregulation of 17beta-hydroxysteroid UDP-glucuronosyltransferase activity|up regulation of UDP glucuronic acid transferase activity|up regulation of 17beta-hydroxysteroid UDP-glucuronosyltransferase activity|up regulation of 4-nitrophenol UDP-glucuronyltransferase activity|upregulation of bilirubin monoglucuronide glucuronyltransferase activity|upregulation of bilirubin uridine diphosphoglucuronyltransferase activity|up-regulation of 4-hydroxybiphenyl UDP-glucuronosyltransferase activity|up regulation of bilirubin glucuronyltransferase activity|activation of morphine glucuronyltransferase activity|positive regulation of uridine diphosphoglucuronate-4-hydroxybiphenyl glucuronosyltransferase activity|activation of 1-naphthol glucuronyltransferase activity|positive regulation of bilirubin UDPGT activity|up-regulation of UDP glucuronic acid transferase activity|positive regulation of uridine diphosphoglucuronate-estriol 16-alpha-glucuronosyltransferase activity|positive regulation of uridine diphosphoglucuronate-1,2-diacylglycerol glucuronosyltransferase activity|upregulation of UDPGA transferase activity|up regulation of uridine diphosphoglucuronate-estriol 16-alpha-glucuronosyltransferase activity|upregulation of 4-nitrophenol UDP-glucuronyltransferase activity|positive regulation of UDPGA transferase activity|activation of uridine 5'-diphosphoglucuronyltransferase activity|activation of 3-OH androgenic UDPGT activity|upregulation of p-nitrophenol UDP-glucuronosyltransferase activity|positive regulation of bilirubin monoglucuronide glucuronyltransferase activity|upregulation of UDP glucuronyltransferase activity|up-regulation of estrone UDPglucuronosyltransferase activity|activation of uridine diphosphoglucuronate-estradiol glucuronosyltransferase activity|activation of GT activity|upregulation of 3-OH androgenic UDPGT activity|up-regulation of phenyl-UDP-glucuronosyltransferase activity|upregulation of UDP glucuronic acid transferase activity|up-regulation of 17-beta-hydroxysteroid UDP-glucuronosyltransferase activity|up-regulation of morphine glucuronyltransferase activity|positive regulation of UDP glucuronic acid transferase activity|activation of p-hydroxybiphenyl UDP glucuronyltransferase activity|up regulation of UDP-glucuronate beta-D-glucuronosyltransferase (acceptor-unspecific)|up regulation of 3-alpha-hydroxysteroid UDP-glucuronosyltransferase activity|activation of 3alpha-hydroxysteroid UDP-glucuronosyltransferase activity|activation of 17beta-hydroxysteroid UDP-glucuronosyltransferase activity|positive regulation of uridine diphosphoglucuronate-bilirubin glucuronoside glucuronosyltransferase activity|up regulation of uridine diphosphoglucuronosyltransferase activity|up-regulation of glucuronosyltransferase activity|upregulation of 3alpha-hydroxysteroid UDP-glucuronosyltransferase activity|up regulation of glucuronosyltransferase activity|up regulation of UDPglucuronate beta-D-glucuronosyltransferase (acceptor-unspecific) activity|up regulation of ciramadol UDP-glucuronyltransferase activity|upregulation of GT activity|activation of UDP-glucuronate-bilirubin glucuronyltransferase activity|upregulation of uridine diphosphate glucuronyltransferase activity|activation of glucuronosyltransferase activity|up-regulation of uridine diphosphoglucuronate-estradiol glucuronosyltransferase activity|positive regulation of UDP glucuronyltransferase activity|positive regulation of 17-OH steroid UDPGT activity|positive regulation of 17beta-hydroxysteroid UDP-glucuronosyltransferase activity|up regulation of UDP glucuronate-estriol glucuronosyltransferase activity|activation of bilirubin glucuronyltransferase activity|upregulation of 17-OH steroid UDPGT activity|up-regulation of estriol UDPglucuronosyltransferase activity|activation of UDP-glucuronyltransferase activity|positive regulation of morphine glucuronyltransferase activity|up-regulation of uridine diphosphoglucuronate-bilirubin glucuronosyltransferase activity|positive regulation of PNP-UDPGT|activation of p-nitrophenol UDP-glucuronyltransferase activity|upregulation of UDP-glucuronate-bilirubin glucuronyltransferase activity|upregulation of bilirubin UDPGT activity|upregulation of UDP glucuronate-estriol glucuronosyltransferase activity|upregulation of UDPglucuronate beta-D-glucuronosyltransferase (acceptor-unspecific) activity|positive regulation of uridine diphosphoglucuronosyltransferase activity|activation of 4-nitrophenol UDPGT activity|up-regulation of p-phenylphenol glucuronyltransferase activity|up regulation of 4-methylumbelliferone UDP-glucuronosyltransferase activity|positive regulation of p-phenylphenol glucuronyltransferase activity|up regulation of bilirubin uridine diphosphoglucuronyltransferase activity|up-regulation of UDP-glucuronate-4-hydroxybiphenyl glucuronosyltransferase activity|activation of phenyl-UDP-glucuronosyltransferase activity|up-regulation of 4-nitrophenol UDP-glucuronyltransferase activity|upregulation of morphine glucuronyltransferase activity|upregulation of glucuronosyltransferase activity|positive regulation of uridine diphosphoglucuronate-estriol glucuronosyltransferase activity|up regulation of UDP-glucuronate-4-hydroxybiphenyl glucuronosyltransferase activity|activation of UDP-glucuronosyltransferase activity|up regulation of UDP-glucuronosyltransferase activity|up-regulation of uridine diphosphoglucuronosyltransferase activity|positive regulation of UDPGA-glucuronyltransferase activity|upregulation of UDP glucuronate-estradiol-glucuronosyltransferase activity|up regulation of 1-naphthol glucuronyltransferase activity|up regulation of morphine glucuronyltransferase activity|up-regulation of uridine diphosphoglucuronate-estriol 16-alpha-glucuronosyltransferase activity|up regulation of p-phenylphenol glucuronyltransferase activity|activation of bilirubin monoglucuronide glucuronyltransferase activity|up regulation of uridine diphosphoglucuronate-1,2-diacylglycerol glucuronosyltransferase activity|up-regulation of pnp-UDPGT activity|up-regulation of UDP glucuronate-estradiol-glucuronosyltransferase activity|up regulation of UDP-glucuronate-bilirubin glucuronyltransferase activity|upregulation of 4-hydroxybiphenyl UDP-glucuronosyltransferase activity|upregulation of uridine 5'-diphosphoglucuronyltransferase activity|up regulation of GT activity|positive regulation of 4-methylumbelliferone UDP-glucuronosyltransferase activity|upregulation of p-hydroxybiphenyl UDP glucuronyltransferase activity|activation of p-nitrophenylglucuronosyltransferase activity|upregulation of 1-naphthol glucuronyltransferase activity|upregulation of p-nitrophenol UDP-glucuronyltransferase activity|positive regulation of 4-hydroxybiphenyl UDP-glucuronosyltransferase activity|up-regulation of 17beta-hydroxysteroid UDP-glucuronosyltransferase activity|up regulation of estriol UDPglucuronosyltransferase activity|up-regulation of uridine diphosphoglucuronate-bilirubin glucuronoside glucuronosyltransferase activity|positive regulation of uridine diphosphoglucuronyltransferase activity|activation of uridine diphosphoglucuronate-bilirubin glucuronosyltransferase activity|positive regulation of UDP-glucuronyltransferase activity|up regulation of PNP-UDPGT|positive regulation of UDP-glucuronate-4-hydroxybiphenyl glucuronosyltransferase activity|activation of PNP-UDPGT|up-regulation of UDPglucuronate beta-D-glucuronosyltransferase (acceptor-unspecific) activity|up-regulation of ciramadol UDP-glucuronyltransferase activity|upregulation of uridine diphosphoglucuronate-1,2-diacylglycerol glucuronosyltransferase activity|positive regulation of UDP-glucuronosyltransferase activity|up-regulation of UDPGA-glucuronyltransferase activity|up-regulation of bilirubin UDP-glucuronosyltransferase activity|up regulation of uridine diphosphoglucuronate-4-hydroxybiphenyl glucuronosyltransferase activity|activation of pnp-UDPGT activity|upregulation of estrone UDPglucuronosyltransferase activity|up-regulation of p-nitrophenol UDP-glucuronosyltransferase activity|up regulation of UDPGA transferase activity|upregulation of 1-naphthol-UDP-glucuronosyltransferase activity|positive regulation of UDPglucuronate beta-D-glucuronosyltransferase (acceptor-unspecific) activity|activation of UDP glucuronyltransferase activity|positive regulation of 1-naphthol-UDP-glucuronosyltransferase activity|positive regulation of p-hydroxybiphenyl UDP glucuronyltransferase activity|positive regulation of UDP glucuronate-estradiol-glucuronosyltransferase activity|activation of p-nitrophenol UDP-glucuronosyltransferase activity|up-regulation of uridine diphosphoglucuronate-4-hydroxybiphenyl glucuronosyltransferase activity|up regulation of bilirubin UDP-glucuronosyltransferase activity|upregulation of pnp-UDPGT activity|upregulation of ciramadol UDP-glucuronyltransferase activity|activation of uridine diphosphoglucuronosyltransferase activity|positive regulation of uridine diphosphate glucuronyltransferase activity|up regulation of uridine diphosphoglucuronate-bilirubin glucuronoside glucuronosyltransferase activity|up-regulation of 4-nitrophenol UDPGT activity|positive regulation of phenyl-UDP-glucuronosyltransferase activity|positive regulation of 1-naphthol glucuronyltransferase activity|upregulation of uridine diphosphoglucuronate-estradiol glucuronosyltransferase activity|up regulation of 4-hydroxybiphenyl UDP-glucuronosyltransferase activity|upregulation of UDP-glucuronyltransferase activity|up-regulation of 3alpha-hydroxysteroid UDP-glucuronosyltransferase activity|up-regulation of 1-naphthol-UDP-glucuronosyltransferase activity|positive regulation of GT activity|positive regulation of 4-nitrophenol UDPGT activity|positive regulation of estrone UDPglucuronosyltransferase activity|positive regulation of UDP glucuronosyltransferase activity|up-regulation of bilirubin UDPGT activity|activation of UDP glucuronate-estradiol-glucuronosyltransferase activity|up-regulation of UDP glucuronyltransferase activity|upregulation of UDP-glucuronosyltransferase activity					i2 UDP-glucuronosyltransferase splice species alter glucuronidation activity of i1 UDP-glucuronosyltransferase splice species		rl	2015-05-15T08:44:32Z					biological_process											owl:Class	
GO:0010792	biolink:NamedThing	DNA double-strand break processing involved in repair via single-strand annealing	The 5' to 3' exonucleolytic resection of the DNA at the site of the break to form a 3' single-strand DNA overhang that results in the repair of a double strand break via single-strand annealing.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0016796	biolink:NamedThing	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	Catalysis of the hydrolysis of ester linkages within nucleic acids by removing nucleotide residues from the 3' or 5' end to yield 5' phosphomonoesters.	tmpzr1t_l9r_go_relaxed.owl	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5' phosphomonoesters				EC:3.1.15.-	Note that this activity can catalyze cleavage of DNA or RNA.								molecular_function											owl:Class	
GO:0018827	biolink:NamedThing	1-chloro-2,2-bis(4-chlorophenyl)ethane dehydrochlorinase activity	Catalysis of the reaction: 1-chloro-2,2-bis(4-chlorophenyl)ethane = HCl + unsym-bis(4-chlorophenyl)ethene. 1-chloro-2,2-bis(4-chlorophenyl)ethane is also known as DDMS; unsym-bis(4-chlorophenyl)ethene is also known as DDNU.	tmpzr1t_l9r_go_relaxed.owl	DDMS dehydrochlorinase activity				EC:4.5.1.-|UM-BBD_reactionID:r0515									molecular_function											owl:Class	
GO:0004056	biolink:NamedThing	argininosuccinate lyase activity	Catalysis of the reaction: N-(L-arginino)succinate = fumarate + L-arginine.	tmpzr1t_l9r_go_relaxed.owl	omega-N-(L-arginino)succinate arginine-lyase activity|2-(Nomega-L-arginino)succinate arginine-lyase (fumarate-forming)|argininosuccinic acid lyase activity|N-(L-argininosuccinate) arginine-lyase activity|2-(omega-N-L-arginino)succinate arginine-lyase (fumarate-forming)|arginosuccinase activity|arginine-succinate lyase activity				Reactome:R-HSA-70573|RHEA:24020|MetaCyc:ARGSUCCINLYA-RXN|EC:4.3.2.1									molecular_function											owl:Class	
GO:0030011	biolink:NamedThing	maintenance of cell polarity	The maintenance of established anisotropic intracellular organization or cell growth patterns.	tmpzr1t_l9r_go_relaxed.owl												GO:0030469|GO:0030013		biological_process											owl:Class	
GO:0099009	biolink:NamedThing	viral genome circularization	The circularization of a viral genome following infection of a host cell. This is common amongst bacterial viruses to protect the viral genome ends from nucleases, to convert the linear genome to an integrative precursor or to give rise to the replicative form of the genome. It can be mediated by covalent closure of the DNA sticky ends, recombinaison between redundant terminal sequences or via the binding of a protein at the viral DNA extremities.	tmpzr1t_l9r_go_relaxed.owl					VZ:3968									biological_process											owl:Class	
GO:0022856	biolink:NamedThing	protein-N(PI)-phosphohistidine-sorbitol phosphotransferase system transporter activity	Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + sorbitol(out) = protein histidine + sorbitol phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.	tmpzr1t_l9r_go_relaxed.owl	sorbitol PTS transporter activity													molecular_function											owl:Class	
GO:0008345	biolink:NamedThing	larval locomotory behavior	Locomotory behavior in a larval (immature) organism.	tmpzr1t_l9r_go_relaxed.owl	larval locomotory behaviour					See also the biological process term 'locomotory behavior ; GO:0007626'.								biological_process											owl:Class	
GO:0071018	biolink:NamedThing	U12-type catalytic step 2 spliceosome	A spliceosomal complex that contains the U12, U5 and U6atac snRNPs bound to a splicing intermediate in which the first catalytic cleavage of the 5' splice site has occurred. The precise subunit composition differs significantly from that of the catalytic step 1, or activated, spliceosome, and includes many proteins in addition to those found in the U12, U5 and U6atac snRNPs.	tmpzr1t_l9r_go_relaxed.owl	AT-AC catalytic step 2 spliceosome|minor catalytic step 2 spliceosome|mammalian U12-type spliceosomal complex C1|yeast U12-type spliceosomal complex A2-2|mammalian U12-type spliceosomal complex C							mah	2009-07-30T12:00:35Z					cellular_component											owl:Class	
GO:1900759	biolink:NamedThing	positive regulation of D-amino-acid oxidase activity	Any process that activates or increases the frequency, rate or extent of D-amino-acid oxidase activity.	tmpzr1t_l9r_go_relaxed.owl	activation of D-amino-acid oxidase activity|positive regulation of D-amino-acid:oxygen oxidoreductase (deaminating)|up-regulation of D-amino-acid oxidase activity|up-regulation of new yellow enzyme|upregulation of L-amino acid:O2 oxidoreductase activity|upregulation of new yellow enzyme|activation of L-amino acid:O2 oxidoreductase activity|up-regulation of D-amino-acid:oxygen oxidoreductase (deaminating)|up regulation of new yellow enzyme|positive regulation of L-amino acid:O2 oxidoreductase activity|upregulation of D-amino-acid oxidase activity|activation of new yellow enzyme|up regulation of D-amino-acid:oxygen oxidoreductase (deaminating)|up-regulation of L-amino acid:O2 oxidoreductase activity|upregulation of D-amino-acid:oxygen oxidoreductase (deaminating)|activation of D-amino-acid:oxygen oxidoreductase (deaminating)|positive regulation of new yellow enzyme|up regulation of D-amino-acid oxidase activity|up regulation of L-amino acid:O2 oxidoreductase activity							pm	2012-05-31T11:24:14Z					biological_process											owl:Class	
GO:0019163	biolink:NamedThing	pyridoxamine-phosphate transaminase activity	Catalysis of the reaction: pyridoxamine 5'-phosphate + 2-oxoglutarate = pyridoxal 5'-phosphate + D-glutamate.	tmpzr1t_l9r_go_relaxed.owl	pyridoxamine 5'-phosphate transaminase activity|pyridoxamine phosphate aminotransferase activity|pyridoxamine-phosphate aminotransferase activity|pyridoxamine-5'-phosphate:2-oxoglutarate aminotransferase (D-glutamate-forming)|pyridoxamine 5'-phosphate-alpha-ketoglutarate transaminase activity				RHEA:15877|MetaCyc:PYRDAMPTRANS-RXN|EC:2.6.1.54									molecular_function											owl:Class	
GO:0110034	biolink:NamedThing	negative regulation of adenylate cyclase-activating glucose-activated G protein-coupled receptor signaling pathway	Any process that stops, prevents, or reduces the frequency, rate or extent of the adenylate cyclase-activating glucose-activated G protein-coupled receptor signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of adenylate cyclase-activating glucose-activated G-protein coupled receptor signaling pathway							kmv	2017-07-17T20:35:55Z					biological_process											owl:Class	
GO:0061059	biolink:NamedThing	positive regulation of peptidoglycan recognition protein signaling pathway	Any process that increases the rate, frequency, or extent of the peptidoglycan recognition protein signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of peptidoglycan recognition protein signalling pathway							dph	2010-03-02T12:37:44Z					biological_process											owl:Class	
GO:0008814	biolink:NamedThing	citrate CoA-transferase activity	Catalysis of the reaction: acetyl-CoA + citrate = acetate + (3S)-citryl-CoA.	tmpzr1t_l9r_go_relaxed.owl	acetyl-CoA:citrate CoA-transferase activity				EC:2.8.3.10|MetaCyc:CITTRANS-RXN|RHEA:19405									molecular_function											owl:Class	
GO:1904586	biolink:NamedThing	cellular response to putrescine	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a putrescine stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to 1,4-Butanediamine|cellular response to 1,4-Diaminobutane|cellular response to tetramethylenediamine							sl	2015-08-20T14:35:45Z					biological_process											owl:Class	
GO:0043707	biolink:NamedThing	cell adhesion involved in single-species biofilm formation in or on host organism	The attachment of a cell to either a host cell or a microbial cell of the same species, or to an underlying host substrate, such as the extracellular matrix, via cell adhesion molecules, occurring during the formation of a biofilm in or on a host species.	tmpzr1t_l9r_go_relaxed.owl	cell adhesion during single-species biofilm formation in or on host organism													biological_process											owl:Class	
GO:0099541	biolink:NamedThing	trans-synaptic signaling by lipid	Cell-cell signaling from post to pre-synapse, across the synaptic cleft, mediated by a lipid.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1901561	biolink:NamedThing	response to benomyl	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a benomyl stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2012-11-02T15:32:33Z					biological_process											owl:Class	
GO:0044730	biolink:NamedThing	bone sialoprotein binding	Binding to a bone sialoprotein, an extracellular matrix glycoprotein found on the surface of bones and dentin.	tmpzr1t_l9r_go_relaxed.owl	bone sialoprotein II binding				InterPro:IPR008412			jl	2012-11-06T13:05:56Z					molecular_function											owl:Class	
GO:0090612	biolink:NamedThing	cAMP deaminase activity	Catalysis of the reaction: cyclic adenosine monophosphate + H2O = cyclic inosine monophosphate + NH3.	tmpzr1t_l9r_go_relaxed.owl	cyclic adenosine monophosphate deaminase activity				EC:3.5.4.46|RHEA:22908			tb	2014-10-23T15:46:42Z					molecular_function											owl:Class	
GO:0047812	biolink:NamedThing	D-amino-acid N-acetyltransferase activity	Catalysis of the reaction: acetyl-CoA + a D-amino acid = CoA + an N-acetyl-D-amino-acid.	tmpzr1t_l9r_go_relaxed.owl	D-amino acid-alpha-N-acetyltransferase activity|acetyl-CoA:D-amino-acid N-acetyltransferase activity|D-amino acid acetyltransferase activity				RHEA:20704|MetaCyc:D-AMINO-ACID-N-ACETYLTRANSFERASE-RXN|EC:2.3.1.36									molecular_function											owl:Class	
GO:0034429	biolink:NamedThing	tectobulbar tract morphogenesis	Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the optic tectum towards target cells in the premotor reticulospinal system in the hindbrain.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0052020	biolink:NamedThing	modification by symbiont of host cell wall	The process in which an organism effects a change in the structure or function of the host cell wall. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	metabolism of host cell wall by organism													biological_process											owl:Class	
GO:0071392	biolink:NamedThing	cellular response to estradiol stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by estradiol, a C18 steroid hormone hydroxylated at C3 and C17 that acts as a potent estrogen.	tmpzr1t_l9r_go_relaxed.owl	cellular response to E2 stimulus							mah	2009-12-11T04:10:31Z					biological_process											owl:Class	
GO:0008754	biolink:NamedThing	O antigen ligase activity	Catalysis of the reaction: Lipid A-core + colanic acid = MLPS.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN0-5294									molecular_function											owl:Class	
GO:0090408	biolink:NamedThing	phloem nitrate loading	The process of loading nitrate into the sieve tube or companion cell of the phloem for long distance transport from source to sink.	tmpzr1t_l9r_go_relaxed.owl								tb	2011-06-01T10:06:21Z					biological_process											owl:Class	
GO:0097675	biolink:NamedThing	SCF-Hrt3/Pof7 ubiquitin ligase complex	An SCF ubiquitin ligase complex in which the F-box protein is Hrt3 in S. cerevisiae (Pof7 in S. pombe).	tmpzr1t_l9r_go_relaxed.owl								pr	2014-10-06T10:31:14Z					cellular_component											owl:Class	
GO:0051743	biolink:NamedThing	red chlorophyll catabolite reductase activity	Catalysis of the reaction: red chlorophyll catabolite + reduced ferredoxin + 2 H+ = primary fluorescent catabolite + oxidized ferredoxin. This reaction is the reduction of the C20/C1 double bond in the pyrrole system of red chlorophyll catabolite (RCC) to a colorless tetrapyrrole (pFCC) with a strong blue fluorescence.	tmpzr1t_l9r_go_relaxed.owl	RCC reductase activity				MetaCyc:RXN-7741|RHEA:24752									molecular_function											owl:Class	
GO:1900210	biolink:NamedThing	positive regulation of cardiolipin metabolic process	Any process that activates or increases the frequency, rate or extent of cardiolipin metabolic process.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of cardiolipin metabolism|upregulation of cardiolipin metabolic process|activation of diphosphatidylglycerol metabolism|activation of cardiolipin metabolism|positive regulation of diphosphatidylglycerol metabolism|up-regulation of cardiolipin metabolic process|positive regulation of cardiolipin metabolism|activation of cardiolipin metabolic process|up regulation of cardiolipin metabolism|up-regulation of diphosphatidylglycerol metabolism|upregulation of cardiolipin metabolism|positive regulation of diphosphatidylglycerol metabolic process|up regulation of cardiolipin metabolic process|up regulation of diphosphatidylglycerol metabolism|up-regulation of diphosphatidylglycerol metabolic process|upregulation of diphosphatidylglycerol metabolic process|up regulation of diphosphatidylglycerol metabolic process|activation of diphosphatidylglycerol metabolic process|upregulation of diphosphatidylglycerol metabolism							jl	2012-03-22T10:43:51Z					biological_process											owl:Class	
GO:0050218	biolink:NamedThing	propionate-CoA ligase activity	Catalysis of the reaction: ATP + propanoate + CoA = AMP + diphosphate + propanoyl-CoA.	tmpzr1t_l9r_go_relaxed.owl	propionyl-CoA synthetase activity|propanoate:CoA ligase (AMP-forming)				RHEA:20373|MetaCyc:PROPIONATE--COA-LIGASE-RXN|EC:6.2.1.17									molecular_function											owl:Class	
GO:0071356	biolink:NamedThing	cellular response to tumor necrosis factor	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tumor necrosis factor stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to TNF							mah	2009-12-11T02:51:37Z					biological_process											owl:Class	
GO:0042905	biolink:NamedThing	9-cis-retinoic acid metabolic process	The chemical reactions and pathways involving 9-cis-retinoic acid, a metabolically active vitamin A derivative.	tmpzr1t_l9r_go_relaxed.owl	9-cis-retinoic acid metabolism													biological_process											owl:Class	
GO:0047058	biolink:NamedThing	vitamin-K-epoxide reductase (warfarin-insensitive) activity	Catalysis of the reaction: 3-hydroxy-2-methyl-3-phytyl-2,3-dihydronaphthoquinone + oxidized dithiothreitol + H2O = 2,3-epoxy-2,3-dihydro-2-methyl-3-phytyl-1,4-naphthoquinone + 1,4-dithiothreitol.	tmpzr1t_l9r_go_relaxed.owl	vitamin K 2,3-epoxide reductase activity	https://github.com/geneontology/go-ontology/issues/21412			MetaCyc:1.1.4.2-RXN|EC:1.17.4.5|RHEA:21560	Formerly EC:1.1.4.2.								molecular_function											owl:Class	
GO:0010385	biolink:NamedThing	double-stranded methylated DNA binding	Binding to double-stranded methylated DNA. Methylation of cytosine or adenine in DNA is an important mechanism for establishing stable heritable epigenetic marks.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0032184	biolink:NamedThing	SUMO polymer binding	Binding to a polymer of the small ubiquitin-like protein SUMO.	tmpzr1t_l9r_go_relaxed.owl	Smt3 polymer binding													molecular_function											owl:Class	
GO:0032183	biolink:NamedThing	SUMO binding	Binding to the small ubiquitin-like protein SUMO.	tmpzr1t_l9r_go_relaxed.owl	Smt3 binding|Smt3 monomer binding													molecular_function											owl:Class	
GO:0015471	biolink:NamedThing	nucleoside-specific channel forming porin activity	Enables the energy independent passage of nucleoside, sized less than 1000 Da, across a membrane. The transmembrane portions of porins consist exclusively of beta-strands which form a beta-barrel. They are found in the outer membranes of Gram-negative bacteria, mitochondria, plastids and possibly acid-fast Gram-positive bacteria.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0043237	biolink:NamedThing	laminin-1 binding	Binding to laminin-1, a glycoprotein trimer with the subunit composition alpha1, beta1, gamma1.	tmpzr1t_l9r_go_relaxed.owl	laminin-111 binding													molecular_function											owl:Class	
GO:0008883	biolink:NamedThing	glutamyl-tRNA reductase activity	Catalysis of the reaction: (S)-4-amino-5-oxopentanoate + NADP(+) + tRNA(Glu) = L-glutamyl-tRNA(Glu) + H(+) + NADPH.	tmpzr1t_l9r_go_relaxed.owl	L-glutamate-semialdehyde: NADP+ oxidoreductase (L-glutamyl-tRNAGlu-forming)				KEGG_REACTION:R04109|MetaCyc:GLUTRNAREDUCT-RXN|RHEA:12344|EC:1.2.1.70									molecular_function											owl:Class	
GO:0010170	biolink:NamedThing	glucose-1-phosphate adenylyltransferase complex	Complex that catalyzes the synthesis of ADP-glucose and pyrophosphate from glucose-1-phosphate and ATP. In plants, the complex is a heterotetramer composed of two types of subunits (small and large). In bacteria, the enzyme complex is composed of four identical subunits.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0034039	biolink:NamedThing	8-oxo-7,8-dihydroguanine DNA N-glycosylase activity	Catalysis of the removal of 8-oxo-7,8-dihydroguanine bases by cleaving the N-C1' glycosidic bond between the oxidized purine and the deoxyribose sugar.	tmpzr1t_l9r_go_relaxed.owl	8-oxoG DNA N-glycosylase activity													molecular_function											owl:Class	
GO:0008534	biolink:NamedThing	oxidized purine nucleobase lesion DNA N-glycosylase activity	Catalysis of the removal of oxidized purine bases by cleaving the N-C1' glycosidic bond between the oxidized purine and the deoxyribose sugar. The reaction involves the formation of a covalent enzyme-substrate intermediate. Release of the enzyme and free base by a beta-elimination or a beta, gamma-elimination mechanism results in the cleavage of the DNA backbone 3' of the apurinic (AP) site.	tmpzr1t_l9r_go_relaxed.owl	2,6-diamino-4-hydroxy-5(N-methyl)formamidopyrimidine-DNA glycosylase activity|DNA-formamidopyrimidine glycosylase activity|DNA glycohydrolase [2,6-diamino-4-hydroxy-5-(N-methyl)formamidopyrimide releasing]|DNA glycosylase/beta-lyase activity|purine-specific oxidized base lesion DNA N-glycosylase activity|Fpg protein|DNA glycosylase/AP-lyase activity|2,6-diamino-4-hydroxy-5N-formamidopyrimidine-DNA glycosylase activity|oxidized purine base lesion DNA N-glycosylase activity|formamidopyrimidine-DNA glycosylase activity|deoxyribonucleate glycosidase activity|8-oxoguanine DNA glycosylase activity|Fapy-DNA glycosylase activity|bifunctional DNA glycosylase activity				MetaCyc:3.2.2.23-RXN|Reactome:R-HSA-110244|EC:3.2.2.23|Reactome:R-HSA-110243|Reactome:R-HSA-110229	Consider also annotating to the molecular function term 'DNA-(apurinic or apyrimidinic site) lyase activity ; GO:0003906'.						GO:0003907		molecular_function											owl:Class	
GO:0102357	biolink:NamedThing	mithramycin dehydrogenase activity	Catalysis of the reaction: mithramycin + NADP <=> mithramycin DK + NADPH + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-13385									molecular_function											owl:Class	
GO:0051178	biolink:NamedThing	meiotic chromosome decondensation	The cell cycle process in which chromosome structure is altered from the condensed form held during meiosis to the relaxed dispersed form held in resting cells.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0033533	biolink:NamedThing	verbascose metabolic process	The chemical reactions and pathways involving verbascose, the pentasaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside.	tmpzr1t_l9r_go_relaxed.owl	verbascose metabolism													biological_process											owl:Class	
GO:0072181	biolink:NamedThing	mesonephric duct formation	The developmental process pertaining to the initial formation of a mesonephric duct. A mesonephric duct is a tube that drains the mesonephros.	tmpzr1t_l9r_go_relaxed.owl	Wolffian duct formation							mah	2010-02-26T02:38:03Z					biological_process											owl:Class	
GO:0072180	biolink:NamedThing	mesonephric duct morphogenesis	The process in which the anatomical structures of the mesonephric duct are generated and organized. A mesonephric duct is a tube drains the mesonephros.	tmpzr1t_l9r_go_relaxed.owl	Wolffian duct morphogenesis							mah	2010-02-26T02:37:13Z					biological_process											owl:Class	
GO:0005966	biolink:NamedThing	cyclic-nucleotide phosphodiesterase complex	An enzyme complex that catalyzes the hydrolysis of bonds in a cyclic nucleotide.	tmpzr1t_l9r_go_relaxed.owl	photoreceptor cyclic-nucleotide phosphodiesterase complex													cellular_component											owl:Class	
GO:0009667	biolink:NamedThing	plastid inner membrane organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the inner membrane of a plastid.	tmpzr1t_l9r_go_relaxed.owl	plastid inner membrane organisation|plastid inner membrane organization and biogenesis													biological_process											owl:Class	
GO:2000158	biolink:NamedThing	positive regulation of ubiquitin-specific protease activity	Any process that activates or increases the frequency, rate or extent of ubiquitin-specific protease (deubiquitinase) activity.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of deubiquitinase activity|positive regulation of UBP|positive regulation of ubiquitin hydrolase activity|positive regulation of UCH2							tb	2010-10-04T10:42:29Z					biological_process											owl:Class	
GO:0031245	biolink:NamedThing	extrinsic component of periplasmic side of cell outer membrane	The component of the cell outer membrane consisting of gene products and protein complexes that are loosely bound to periplasmic surface, but not integrated into the hydrophobic region.	tmpzr1t_l9r_go_relaxed.owl	extrinsic to internal leaflet of cell outer membrane|extrinsic to internal side of outer membrane|extrinsic to periplasmic side of cell outer membrane|extrinsic to internal side of cell outer membrane													cellular_component											owl:Class	
GO:0070501	biolink:NamedThing	poly-gamma-glutamate biosynthetic process	The chemical reactions and pathways resulting in the formation of poly-gamma-glutamate, a polymer of D- and/or L-glutamic acid residues linked by gamma-peptidyl bonds.	tmpzr1t_l9r_go_relaxed.owl	poly-gamma-glutamate anabolism|poly-gamma-glutamate biosynthesis|poly-gamma-glutamate formation|poly-gamma-glutamate synthesis													biological_process											owl:Class	
GO:0070500	biolink:NamedThing	poly-gamma-glutamate metabolic process	The chemical reactions and pathways involving poly-gamma-glutamate, a polymer of D- and/or L-glutamic acid residues linked by gamma-peptidyl bonds.	tmpzr1t_l9r_go_relaxed.owl	poly-gamma-glutamate metabolism													biological_process											owl:Class	
GO:0062073	biolink:NamedThing	histone mRNA stem-loop binding complex	A protein-containing complex composed of a stem-loop binding protein (in most species SLBP) and its interacting partner (SLIP1 or MIF4GD in most species) that binds to the histone mRNA (hmRNA) 3-prime-stem-loop structure. Facilitates hmRNA translation initiation and may also be involved in its processing and nuclear export.	tmpzr1t_l9r_go_relaxed.owl	SLBP-SLIP1 complex|SLBP-MIF4GD complex							dph	2018-09-10T13:46:56Z					cellular_component											owl:Class	
GO:0051795	biolink:NamedThing	positive regulation of timing of catagen	Any process that activates or increases the frequency, rate or extent of timing of catagen, the regression phase of the hair cycle.	tmpzr1t_l9r_go_relaxed.owl	up regulation of catagen|up-regulation of catagen|upregulation of catagen|activation of catagen|positive regulation of catagen|stimulation of catagen													biological_process											owl:Class	
GO:0070817	biolink:NamedThing	P-TEFb-cap methyltransferase complex localization	Any process in which the P-TEFb-cap methyltransferase complex is transported to, or maintained in, a specific location.	tmpzr1t_l9r_go_relaxed.owl	P-TEFb-cap methyltransferase complex localisation|establishment and maintenance of P-TEFb-cap methyltransferase complex localization							mah	2009-07-13T04:20:17Z					biological_process											owl:Class	
GO:1903219	biolink:NamedThing	negative regulation of malate dehydrogenase (decarboxylating) (NADP+) activity	Any process that stops, prevents or reduces the frequency, rate or extent of malate dehydrogenase (decarboxylating) (NADP+) activity.	tmpzr1t_l9r_go_relaxed.owl	down regulation of NADP-specific malate dehydrogenase activity|negative regulation of 'malic' enzyme|inhibition of L-malate:NADP oxidoreductase activity|down regulation of NADP-specific malic enzyme|inhibition of malate dehydrogenase (decarboxylating, NADP)|down-regulation of NADP-linked decarboxylating malic enzyme|negative regulation of (S)-malate:NADP+ oxidoreductase (oxaloacetate-decarboxylating)|down-regulation of L-malate:NADP oxidoreductase activity|inhibition of NADP-malic enzyme activity|negative regulation of malate dehydrogenase (NADP, decarboxylating)|down regulation of malate dehydrogenase (NADP, decarboxylating)|negative regulation of NADP-specific malic enzyme|downregulation of 'malic' enzyme|inhibition of malate dehydrogenase (decarboxylating) (NADP+) activity|down-regulation of malate dehydrogenase (decarboxylating) (NADP+) activity|downregulation of (S)-malate:NADP+ oxidoreductase (oxaloacetate-decarboxylating)|down regulation of malate dehydrogenase (decarboxylating, NADP)|negative regulation of L-malate:NADP oxidoreductase activity|inhibition of malate dehydrogenase (NADP, decarboxylating)|negative regulation of NADP-malic enzyme activity|negative regulation of NADP-linked decarboxylating malic enzyme|down-regulation of NADP-specific malic enzyme|inhibition of (S)-malate:NADP+ oxidoreductase (oxaloacetate-decarboxylating)|down regulation of L-malate:NADP oxidoreductase activity|inhibition of NADP-specific malic enzyme|downregulation of NADP-specific malic enzyme|down regulation of 'malic' enzyme|downregulation of malate dehydrogenase (decarboxylating, NADP)|down regulation of malate dehydrogenase (decarboxylating) (NADP+) activity|down-regulation of (S)-malate:NADP+ oxidoreductase (oxaloacetate-decarboxylating)|down-regulation of NADP-malic enzyme activity|downregulation of L-malate:NADP oxidoreductase activity|down regulation of (S)-malate:NADP+ oxidoreductase (oxaloacetate-decarboxylating)|negative regulation of NADP-specific malate dehydrogenase activity|down-regulation of malate dehydrogenase (decarboxylating, NADP)|inhibition of 'malic' enzyme|downregulation of malate dehydrogenase (decarboxylating) (NADP+) activity|inhibition of NADP-linked decarboxylating malic enzyme|inhibition of NADP-specific malate dehydrogenase activity|downregulation of NADP-specific malate dehydrogenase activity|downregulation of malate dehydrogenase (NADP, decarboxylating)|down regulation of NADP-linked decarboxylating malic enzyme|downregulation of NADP-linked decarboxylating malic enzyme|down-regulation of 'malic' enzyme|down-regulation of malate dehydrogenase (NADP, decarboxylating)|down-regulation of NADP-specific malate dehydrogenase activity|negative regulation of malate dehydrogenase (decarboxylating, NADP)|downregulation of NADP-malic enzyme activity|down regulation of NADP-malic enzyme activity							sart	2014-07-24T11:17:28Z					biological_process											owl:Class	
GO:0031716	biolink:NamedThing	calcitonin receptor binding	Binding to a calcitonin receptor.	tmpzr1t_l9r_go_relaxed.owl	calcitonin receptor ligand													molecular_function											owl:Class	
GO:1904389	biolink:NamedThing	rod bipolar cell differentiation	The process in which a relatively unspecialized cell acquires the specialized features of a rod bipolar cell.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-06-23T19:01:11Z					biological_process											owl:Class	
GO:0018911	biolink:NamedThing	1,2,4-trichlorobenzene metabolic process	The chemical reactions and pathways involving 1,2,4-trichlorobenzene, a derivative of benzene with chlorine atoms attached to positions 1, 2 and 4 of the ring. It is a colorless liquid used as a solvent in chemical manufacturing, in dyes and intermediates, dielectric fluid, synthetic transformer oils, lubricants, heat-transfer medium and insecticides.	tmpzr1t_l9r_go_relaxed.owl	1,2,4-trichlorobenzene metabolism				UM-BBD_pathwayID:tbz									biological_process											owl:Class	
GO:0048189	biolink:NamedThing	Lid2 complex	A protein complex involved in regulation of chromatin remodeling. In Schizosaccharomyces the complex contains Lid2, Ash2, Jmj3, Snt2, and Sdc1.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/22010												cellular_component											owl:Class	
GO:0102901	biolink:NamedThing	isopimaradienol hydroxylase activity	Catalysis of the reaction: H+ + isopimaradienol + NADPH + O2 <=> isopimaradiene-diol + NADP + H2O.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-8536									molecular_function											owl:Class	
GO:1905007	biolink:NamedThing	positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation	Any process that activates or increases the frequency, rate or extent of epithelial to mesenchymal transition involved in endocardial cushion formation.	tmpzr1t_l9r_go_relaxed.owl	upregulation of epithelial to mesenchymal transition involved in endocardial cushion formation|up-regulation of epithelial to mesenchymal transition involved in endocardial cushion formation|activation of epithelial to mesenchymal transition involved in endocardial cushion formation|up regulation of epithelial to mesenchymal transition involved in endocardial cushion formation							rl	2016-03-01T15:38:54Z					biological_process											owl:Class	
GO:0038140	biolink:NamedThing	ERBB4-ERBB3 complex	A heterodimeric complex between the tyrosine kinase receptors ERBB4 (also called HER4) and ERBB3 (also called HER3). ERBB3 has impaired kinase activity so relies on the kinase activity of its heterodimer partner for activation and signal transmission.	tmpzr1t_l9r_go_relaxed.owl	ERBB4:ERBB3 heterodimer|ERBB3-ERBB4 complex							bf	2012-03-30T02:04:16Z					cellular_component											owl:Class	
GO:0004731	biolink:NamedThing	purine-nucleoside phosphorylase activity	Catalysis of the reaction: purine nucleoside + phosphate = purine + alpha-D-ribose 1-phosphate.	tmpzr1t_l9r_go_relaxed.owl	purine deoxynucleoside phosphorylase activity|inosine-guanosine phosphorylase activity|purine nucleoside phosphorylase activity|purine-nucleoside:phosphate ribosyltransferase activity|inosine phosphorylase activity|purine ribonucleoside phosphorylase activity|PUNPII|PUNPI|purine deoxyribonucleoside phosphorylase activity|PNPase activity				Reactome:R-HSA-74249|RHEA:19805|EC:2.4.2.1|Reactome:R-HSA-112033|MetaCyc:PNP-RXN|Reactome:R-HSA-74242|Reactome:R-HSA-112034									molecular_function											owl:Class	
GO:0071891	biolink:NamedThing	N-terminal peptidyl-proline dimethylation involved in translation	An N-terminal peptidyl-proline dimethylation process that contributes to translation.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-09-14T02:19:40Z					biological_process											owl:Class	
GO:2000383	biolink:NamedThing	regulation of ectoderm development	Any process that modulates the frequency, rate or extent of ectoderm development.	tmpzr1t_l9r_go_relaxed.owl								vk	2011-02-15T03:17:10Z					biological_process											owl:Class	
GO:0071760	biolink:NamedThing	IgY immunoglobulin complex	A protein complex composed of two identical immunoglobulin heavy chains of the IgY isotype and two identical immunoglobulin light chains, held together by disulfide bonds. An IgY immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.	tmpzr1t_l9r_go_relaxed.owl						Note that an IgY immunoglobulin complex has the function of antigen binding if a suitable antigen is available. Note that IgY is found in amphibians, reptiles, and birds.		mah	2010-03-24T01:44:53Z					cellular_component											owl:Class	
GO:0033832	biolink:NamedThing	alpha,alpha-trehalose phosphorylase (configuration-retaining) activity	Catalysis of the reaction: alpha,alpha-trehalose + phosphate = alpha-D-glucose + alpha-D-glucose 1-phosphate.	tmpzr1t_l9r_go_relaxed.owl	trehalose phosphorylase activity|alpha,alpha-trehalose:phosphate alpha-D-glucosyltransferase activity				RHEA:16257|MetaCyc:RXN-4441									molecular_function											owl:Class	
GO:0070678	biolink:NamedThing	preprotein binding	Binding to a preprotein, the unprocessed form of a protein destined to undergo co- or post-translational processing.	tmpzr1t_l9r_go_relaxed.owl	unprocessed protein binding							mah	2009-05-29T03:41:54Z					molecular_function											owl:Class	
GO:0032171	biolink:NamedThing	germ tube septin cap	A faint structure formed of septins found at the leading edge of growth in germ tubes of fungal cells growing filamentously. This cap of septins colocalizes with a region of the plasma membrane that is rich in ergosterol.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0018049	biolink:NamedThing	C-terminal peptidyl-serine amidation	The formation of a C-terminal peptidyl-serine amide by hydrolysis and oxidation of an interior Ser-Gly peptide in a secreted protein.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0096									biological_process											owl:Class	
GO:0019807	biolink:NamedThing	aspartoacylase activity	Catalysis of the reaction: N-acyl-L-aspartate + H2O = a fatty acid anion + L-aspartate.	tmpzr1t_l9r_go_relaxed.owl	acylase II|N-acetylaspartate amidohydrolase activity|acetyl-aspartic deaminase activity|aminoacylase II activity|N-acyl-L-aspartate amidohydrolase activity				MetaCyc:ASPARTOACYLASE-RXN|EC:3.5.1.15|RHEA:10872|Reactome:R-HSA-5691507									molecular_function											owl:Class	
GO:0008770	biolink:NamedThing	[acyl-carrier-protein] phosphodiesterase activity	Catalysis of the reaction: [acyl-carrier protein] + H2O = 4'-phosphopantetheine + apoprotein.	tmpzr1t_l9r_go_relaxed.owl	ACP phosphodiesterase activity|AcpH|holo-acyl-carrier-protein 4'-pantetheine-phosphohydrolase activity|ACP hydrolyase activity|acyl-carrier-protein 4'-pantetheine-phosphohydrolase activity|[acyl-carrier-protein] 4'-pantetheine-phosphohydrolase activity|[acyl-carrier protein] phosphodiesterase activity|acyl-carrier-protein phosphodiesterase activity				MetaCyc:3.1.4.14-RXN|EC:3.1.4.14|RHEA:20537									molecular_function											owl:Class	
GO:0098744	biolink:NamedThing	1-phosphatidylinositol 4-kinase activator activity	Binds to and increases the activity of 1-phosphatidylinositol 4-kinase.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1900135	biolink:NamedThing	positive regulation of renin secretion into blood stream	Any process that activates or increases the frequency, rate or extent of renin secretion into blood stream.	tmpzr1t_l9r_go_relaxed.owl	up regulation of renin release into blood stream|up regulation of renin secretion into blood stream|upregulation of renin secretion into blood stream|upregulation of renin release into blood stream|activation of renin release into blood stream|up-regulation of renin release into blood stream|positive regulation of renin release into blood stream|activation of renin secretion into blood stream|up-regulation of renin secretion into blood stream							rph	2012-02-27T10:32:08Z					biological_process											owl:Class	
GO:0016851	biolink:NamedThing	magnesium chelatase activity	Catalysis of the reaction: ATP + H(2)O + Mg(2+) + protoporphyrin IX = ADP + 2 H(+) + magnesium protoporphyrin IX + phosphate.	tmpzr1t_l9r_go_relaxed.owl	Mg-chelatase activity|magnesium-protoporphyrin IX chelatase activity|protoporphyrin IX magnesium-chelatase activity|Mg-protoporphyrin IX magnesio-lyase activity|magnesium-protoporphyrin chelatase activity|Mg-protoporphyrin IX chelatase activity|magnesium-chelatase activity|Mg-protoporphyrin IX magnesium-lyase activity|protoporphyrin IX Mg-chelatase activity				MetaCyc:RXN1F-20|RHEA:13961|EC:6.6.1.1|KEGG_REACTION:R03877	Note that this was EC:4.99.1.1.								molecular_function											owl:Class	
GO:0034544	biolink:NamedThing	trans-ACOHDA hydrolase activity	Catalysis of the reaction: trans-4-amino-6-carboxy-2-oxo-hexa-3,5-dienoate + H2O = fumarylpyruvate + NH3.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0810|EC:3.5.99.-									molecular_function											owl:Class	
GO:0050328	biolink:NamedThing	tetrahydroberberine oxidase activity	Catalysis of the reaction: (S)-tetrahydroberberine + 2 O2 = berberine + 2 H2O2.	tmpzr1t_l9r_go_relaxed.owl	(S)-tetrahydroberberine:oxygen oxidoreductase activity|(S)-THB oxidase activity|THB oxidase activity				RHEA:13489|EC:1.3.3.8|MetaCyc:TETRAHYDROBERBERINE-OXIDASE-RXN									molecular_function											owl:Class	
GO:0050126	biolink:NamedThing	N-carbamoylputrescine amidase activity	Catalysis of the reaction: N-carbamoylputrescine + H(2)O + 2 H(+) = CO(2) + NH(4)(+) + putrescine.	tmpzr1t_l9r_go_relaxed.owl	carbamoylputrescine hydrolase activity|NCP|N-carbamoylputrescine amidohydrolase activity				EC:3.5.1.53|KEGG_REACTION:R01152|RHEA:22284|MetaCyc:N-CARBAMOYLPUTRESCINE-AMIDASE-RXN									molecular_function											owl:Class	
GO:0044350	biolink:NamedThing	micropinocytosis	An endocytosis process that results in the uptake of liquid material by cells from their external environment by invagination of the plasma membrane to form uncoated micropinosomes, differentiated from macropinosomes by their smaller size, on average 95 nm.	tmpzr1t_l9r_go_relaxed.owl	single-organism micropinocytosis|clathrin-independent pinocytosis							jl	2013-12-02T14:26:30Z			GO:1902540		biological_process											owl:Class	
GO:0031363	biolink:NamedThing	N-terminal protein amino acid deamination	The removal of an amino group from the N-terminal amino acid residue of a protein.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0042018	biolink:NamedThing	interleukin-22 receptor activity	Combining with interleukin-22 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	IL-22R|IL-22 receptor activity													molecular_function											owl:Class	
GO:0034366	biolink:NamedThing	spherical high-density lipoprotein particle	A mature high-density lipoprotein (HDL) particle, converted from discoidal HDL particles following the esterification of cholesterol in the particle by phosphatidylcholine-sterol O-acyltransferase (lecithin cholesterol acyltransferase; LCAT).	tmpzr1t_l9r_go_relaxed.owl	mature high-density lipoprotein particle|mature HDL|spherical HDL													cellular_component											owl:Class	
GO:0071720	biolink:NamedThing	sodium-independent prostaglandin transport	The directed, sodium-independent, movement of prostaglandins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-03-10T03:09:10Z					biological_process											owl:Class	
GO:0070552	biolink:NamedThing	BRISC complex	A protein complex that contains the FAM175B/ABRO1, BRCC3/BRCC36, BRE/BRCC45 and MERIT40/NBA1 proteins, and specifically cleaves K63-linked polyubiquitin chains.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0061345	biolink:NamedThing	planar cell polarity pathway involved in cardiac muscle cell fate commitment	The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via effectors other than beta-catenin and contributing to a cardioblast being committed to a cardiac muscle cell fate.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-09-30T12:39:05Z					biological_process											owl:Class	
GO:0090624	biolink:NamedThing	endoribonuclease activity, cleaving miRNA-paired mRNA	Catalysis of the endonucleolytic cleavage of the mRNA in a double-stranded RNA molecule formed by the base pairing of an mRNA with an miRNA.	tmpzr1t_l9r_go_relaxed.owl								tb	2015-01-21T16:28:52Z					molecular_function											owl:Class	
GO:0008710	biolink:NamedThing	8-amino-7-oxononanoate synthase activity	Catalysis of the reaction: L-alanine + H(+) + pimelyl-CoA = 8-amino-7-oxononanoate + CO(2) + CoA.	tmpzr1t_l9r_go_relaxed.owl	7-keto-8-aminopelargonic synthetase activity|8-amino-7-oxopelargonate synthase activity|7-KAP synthetase activity|8-amino-7-ketopelargonate synthase activity|AONS activity|7-keto-8-amino-pelargonic acid synthetase activity|6-carboxyhexanoyl-CoA:L-alanine C-carboxyhexanoyltransferase (decarboxylating)|7-keto-8-aminopelargonic acid synthetase activity				RHEA:20712|EC:2.3.1.47|MetaCyc:7KAPSYN-RXN|KEGG_REACTION:R03210									molecular_function											owl:Class	
GO:0048620	biolink:NamedThing	post-embryonic hindgut morphogenesis	The process in which the anatomical structures of the hindgut are generated and organized, during the post-embryonic phase.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1904790	biolink:NamedThing	regulation of shelterin complex assembly	Any process that modulates the frequency, rate or extent of shelterin complex assembly.	tmpzr1t_l9r_go_relaxed.owl	regulation of Pot1 complex assembly|regulation of telosome assembly|regulation of shelterin complex formation|regulation of Pot1-Tpz1 complex assembly							nc	2015-11-06T16:13:03Z					biological_process											owl:Class	
GO:0033484	biolink:NamedThing	nitric oxide homeostasis	A homeostatic process involved in the maintenance of an internal steady state of nitric oxide within an organism or cell.	tmpzr1t_l9r_go_relaxed.owl	NO homeostasis													biological_process											owl:Class	
GO:0015699	biolink:NamedThing	antimonite transport	The directed movement of antimonite into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0034228	biolink:NamedThing	ethanolamine transmembrane transporter activity	Enables the transfer of ethanolamine from one side of a membrane to the other. Ethanolamine (2-aminoethanol, monoethanolamine) is an amino alcohol that occurs widely in living organisms as a constituent of certain types of phospholipids, such as phosphatidylethanolamine.	tmpzr1t_l9r_go_relaxed.owl	2-aminoethanol transmembrane transporter activity|ethanolamine permease activity|monoethanolamine transmembrane transporter activity				RHEA:32747									molecular_function											owl:Class	
GO:0010157	biolink:NamedThing	response to chlorate	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chlorate stimulus.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1901048	biolink:NamedThing	transforming growth factor beta receptor signaling pathway involved in regulation of multicellular organism growth	A series of molecular signals initiated by the binding of an extracellular ligand to a transforming growth factor beta receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription, that modulates the frequency, rate or extent of growth of the body of an organism so that it reaches its usual body size.	tmpzr1t_l9r_go_relaxed.owl	TGF-beta receptor signaling pathway of regulation of body growth|transforming growth factor beta receptor signaling pathway of regulation of body growth|TGFbeta receptor signalling pathway of regulation of body size|TGFbeta receptor signaling pathway of regulation of body size|TGFbeta receptor signalling pathway of regulation of multicellular organism growth|TGFbeta receptor signaling pathway of regulation of body growth|TGF-beta receptor signalling pathway of regulation of multicellular organism growth|transforming growth factor beta receptor signalling pathway of regulation of multicellular organism growth|transforming growth factor beta receptor signaling pathway of regulation of multicellular organism growth|transforming growth factor beta receptor signalling pathway of regulation of body growth|TGFbeta receptor signalling pathway of regulation of body growth|transforming growth factor beta receptor signalling pathway of regulation of body size|TGFbeta receptor signaling pathway of regulation of multicellular organism growth|TGF-beta receptor signalling pathway of regulation of body growth|TGF-beta receptor signaling pathway of regulation of body size|TGF-beta receptor signaling pathway of regulation of multicellular organism growth|TGF-beta receptor signalling pathway of regulation of body size|transforming growth factor beta receptor signaling pathway of regulation of body size							kmv	2012-06-27T07:37:22Z					biological_process											owl:Class	
GO:0099119	biolink:NamedThing	3-demethylubiquinol-8 3-O-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + 3-demethylubiquinol-8 = S-adenosyl-L-homocysteine + ubiquinol-8.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0018786	biolink:NamedThing	haloalkane dehalogenase activity	Catalysis of the reaction: 1-haloalkane + H2O = a primary alcohol + halide.	tmpzr1t_l9r_go_relaxed.owl	1-haloalkane dehalogenase activity|1-chlorohexane halidohydrolase activity|1-haloalkane halidohydrolase activity				RHEA:19081|MetaCyc:HALOALKANE-DEHALOGENASE-RXN|UM-BBD_enzymeID:e0003|EC:3.8.1.5									molecular_function											owl:Class	
GO:0047383	biolink:NamedThing	guanidinodeoxy-scyllo-inositol-4-phosphatase activity	Catalysis of the reaction: 1-guanidino-1-deoxy-scyllo-inositol 4-phosphate + H(2)O = 1-guanidino-1-deoxy-scyllo-inositol + phosphate.	tmpzr1t_l9r_go_relaxed.owl	1-guanidino-1-deoxy-scyllo-inositol-4-P phosphohydrolase activity|1-guanidino-scyllo-inositol 4-phosphatase activity|1-guanidino-1-deoxy-scyllo-inositol-4-phosphate 4-phosphohydrolase activity				RHEA:15777|MetaCyc:3.1.3.40-RXN|EC:3.1.3.40|KEGG_REACTION:R03496									molecular_function											owl:Class	
GO:0048619	biolink:NamedThing	embryonic hindgut morphogenesis	The process in which the anatomical structures of the hindgut are generated and organized, during the embryonic phase.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0000292	biolink:NamedThing	RNA fragment catabolic process	The chemical reactions and pathways resulting in the breakdown of a fragment of RNA, such as excised introns or sequences removed from ribosomal RNA during processing.	tmpzr1t_l9r_go_relaxed.owl	RNA fragment degradation|RNA fragment catabolism|group I intron catabolic process|RNA fragment breakdown											GO:0030452		biological_process											owl:Class	
GO:0060121	biolink:NamedThing	vestibular receptor cell stereocilium organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a stereocilium. A stereocilium is an actin-based protrusion from the apical surface of vestibular hair cells.	tmpzr1t_l9r_go_relaxed.owl	vestibular receptor cell stereocilium organisation|vestibular receptor cell stereocilium organization and biogenesis|vestibular hair cell stereocilium organization													biological_process											owl:Class	
GO:0036338	biolink:NamedThing	viral membrane	The lipid bilayer of a virion, a complete fully infectious extracellular virus particle.	tmpzr1t_l9r_go_relaxed.owl								bf	2012-09-07T13:28:21Z					cellular_component											owl:Class	
GO:0140366	biolink:NamedThing	galectin lattice	A non-stoichiometric protein complex formed by several galectins crosslinking glycosylated ligands to form a dynamic lattice. The galectin lattice modulates receptor kinase signaling and the functionality of membrane receptors, by regulating the diffusion, compartmentalization and endocytosis of plasma membrane glycoproteins and glycolipids.	tmpzr1t_l9r_go_relaxed.owl								pg	2019-07-25T19:35:05Z					cellular_component											owl:Class	
GO:0003035	biolink:NamedThing	detection of increased carbon dioxide by carotid body chemoreceptor signaling	The process in which information about the levels of carbon dioxide are received and are converted to a molecular signal by chemoreceptors in a carotid body.	tmpzr1t_l9r_go_relaxed.owl	detection of increased carbon dioxide by carotid body chemoreceptor signalling													biological_process											owl:Class	
GO:0016501	biolink:NamedThing	prostacyclin receptor activity	Combining with prostacyclin (PGI(2)) to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	PGI receptor activity|prostaglandin I receptor activity|PGI(2) receptor activity											GO:0004959		molecular_function											owl:Class	
GO:0080072	biolink:NamedThing	spermidine:sinapoyl CoA N-acyltransferase activity	Catalysis of the transfer of a sinapoyl group to a nitrogen atom on the spermidine molecule.	tmpzr1t_l9r_go_relaxed.owl								dhl	2009-04-13T04:16:28Z					molecular_function											owl:Class	
GO:0033462	biolink:NamedThing	GGC codon-amino acid adaptor activity	A triplet codon-amino acid adaptor activity that recognizes a GGC codon.	tmpzr1t_l9r_go_relaxed.owl	glycine tRNA					Note that in the standard genetic code, GGC codes for glycine.								molecular_function											owl:Class	
GO:0050816	biolink:NamedThing	phosphothreonine residue binding	Binding to a phosphorylated threonine residue within a protein.	tmpzr1t_l9r_go_relaxed.owl	phosphothreonine binding													molecular_function											owl:Class	
GO:0002192	biolink:NamedThing	IRES-dependent translational initiation of linear mRNA	The process where translation initiation recruits the 40S ribosomal subunits via an internal ribosome entry segment (IRES) before an AUG codon is encountered in an appropriate sequence context to initiate linear mRNA translation.	tmpzr1t_l9r_go_relaxed.owl								hjd	2011-08-11T02:32:45Z					biological_process											owl:Class	
GO:1901612	biolink:NamedThing	cardiolipin binding	Binding to cardiolipin.	tmpzr1t_l9r_go_relaxed.owl								kmv	2012-11-12T21:19:50Z					molecular_function											owl:Class	
GO:0052621	biolink:NamedThing	diguanylate cyclase activity	Catalysis of the reaction: 2 GTP = cyclic di-3',5'-guanylate + 2 diphosphate + 2 H(+).	tmpzr1t_l9r_go_relaxed.owl	GTP:GTP guanylyltransferase activity				RHEA:24898|EC:2.7.7.65|MetaCyc:RXN0-5359|KEGG_REACTION:R08057							GO:0043789		molecular_function											owl:Class	
GO:0042962	biolink:NamedThing	acridine:proton antiporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + acridine(in) = H+(in) + acridine(out).	tmpzr1t_l9r_go_relaxed.owl	acridine efflux pump activity|acridine:hydrogen antiporter activity													molecular_function											owl:Class	
GO:0070157	biolink:NamedThing	mitochondrial prolyl-tRNA aminoacylation	The process of coupling proline to prolyl-tRNA in a mitochondrion, catalyzed by prolyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0015710	biolink:NamedThing	tellurite transport	The directed movement of tellurite into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1903495	biolink:NamedThing	cellular response to dehydroepiandrosterone	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dehydroepiandrosterone stimulus.	tmpzr1t_l9r_go_relaxed.owl								mr	2014-09-25T17:01:26Z					biological_process											owl:Class	
GO:0001596	biolink:NamedThing	angiotensin type I receptor activity	An angiotensin receptor activity that acts via Gq-mediated activation of phospholipase C followed by phosphoinositide hydrolysis and Ca2+ signaling, and may act via additional signaling mechanisms.	tmpzr1t_l9r_go_relaxed.owl	PLC-activating angiotensin receptor activity													molecular_function											owl:Class	
GO:0110035	biolink:NamedThing	rDNA spacer replication fork barrier binding, bending	The activity of binding selectively, and in a sequence-specific manner, a replication fork barrier found in rDNA spacers, and distorting the original structure of DNA, typically a straight helix, into a bend, or increasing the bend if the original structure was intrinsically bent due to its sequence.	tmpzr1t_l9r_go_relaxed.owl								kmv	2017-07-17T21:09:50Z					molecular_function											owl:Class	
GO:0031767	biolink:NamedThing	gastric inhibitory polypeptide receptor binding	Binding to a gastric inhibitory polypeptide receptor.	tmpzr1t_l9r_go_relaxed.owl	gastric inhibitory polypeptide receptor ligand													molecular_function											owl:Class	
GO:0070115	biolink:NamedThing	organellar chromatophore intermembrane space	The region between the inner and outer lipid bilayers that surround an organellar chromatophore.	tmpzr1t_l9r_go_relaxed.owl	Paulinella-type chromatophore intermembrane space													cellular_component											owl:Class	
GO:0008574	biolink:NamedThing	plus-end-directed microtubule motor activity	A motor activity that generates movement along a microtubule toward the plus end, driven by ATP hydrolysis.	tmpzr1t_l9r_go_relaxed.owl	ATP-dependent microtubule motor activity, plus-end-directed|ATP-dependent plus-end-directed microtubule motor activity|kinesin ATP phosphohydrolase (plus-end-directed)|kinesin activity|plus-end-directed kinesin ATPase activity|microtubule motor activity, plus-end-directed|plus-end-directed ATP-dependent microtubule motor activity	https://github.com/geneontology/go-ontology/issues/18664			EC:5.6.1.3|MetaCyc:3.6.4.4-RXN									molecular_function											owl:Class	
GO:0018063	biolink:NamedThing	cytochrome c-heme linkage	The linkage of cytochromes and other heme proteins to heme.	tmpzr1t_l9r_go_relaxed.owl	cytochrome c-haem linkage				RESID:AA0135|RESID:AA0134									biological_process											owl:Class	
GO:0044820	biolink:NamedThing	mitotic telomere tethering at nuclear periphery	The process in which a telomere is maintained in a specific location at the nuclear periphery, as part of a mitotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl								jl	2013-11-19T16:16:22Z					biological_process											owl:Class	
GO:0034398	biolink:NamedThing	telomere tethering at nuclear periphery	The process in which a telomere is maintained in a specific location at the nuclear periphery.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0030294	biolink:NamedThing	receptor signaling protein tyrosine kinase inhibitor activity	Stops, prevents or reduces the activity of a receptor signaling protein tyrosine kinase.	tmpzr1t_l9r_go_relaxed.owl	receptor signalling protein tyrosine kinase inhibitor activity													molecular_function											owl:Class	
GO:0110120	biolink:NamedThing	gamma-tubulin complex localization to nuclear side of mitotic spindle pole body	Any process in which a gamma-tubulin complex is transported to, or maintained in, a specific location at the nuclear side of the mitotic spindle pole body.	tmpzr1t_l9r_go_relaxed.owl								kmv	2018-07-27T15:42:46Z					biological_process											owl:Class	
GO:0047552	biolink:NamedThing	2-oxoaldehyde dehydrogenase (NADP+) activity	Catalysis of the reaction: a 2-oxoaldehyde + NADP+ + H2O = a 2-oxo acid + NADPH + H+.	tmpzr1t_l9r_go_relaxed.owl	NADP-dependent alpha-ketoaldehyde dehydrogenase activity|2-ketoaldehyde dehydrogenase|alpha-ketoaldehyde dehydrogenase activity|NADP-linked alpha-ketoaldehyde dehydrogenase activity|methylglyoxal dehydrogenase activity|2-oxoaldehyde:NADP+ 2-oxidoreductase activity				EC:1.2.1.49|MetaCyc:2-OXOALDEHYDE-DEHYDROGENASE-NADP+-RXN|RHEA:18129									molecular_function											owl:Class	
GO:0033721	biolink:NamedThing	aldehyde dehydrogenase (NADP+) activity	Catalysis of the reaction: an aldehyde + NADP+ + H2O = an acid + NADPH + H+.	tmpzr1t_l9r_go_relaxed.owl	NADP-dependent aldehyde dehydrogenase activity|aldehyde:NADP+ oxidoreductase activity|NADP-acetaldehyde dehydrogenase activity				EC:1.2.1.4|MetaCyc:ALDEHYDE-DEHYDROGENASE-NADP+-RXN|RHEA:11888									molecular_function											owl:Class	
GO:0007384	biolink:NamedThing	specification of segmental identity, thorax	The specification of the characteristic structures of the thoracic segments following establishment of segment boundaries. Identity is considered to be the aggregate of characteristics by which a structure is recognized.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0090536	biolink:NamedThing	NoRC complex	An ISWI complex that contains an ATPase subunit of the ISWI family (specifically SNF2H in mammals, which contain two ISWI homologs) and a Tip5 homolog. In mammals, NoRC is involved in regulation of transcription from RNAP I and RNA polymerase III promoters.	tmpzr1t_l9r_go_relaxed.owl								tb	2013-02-11T14:07:14Z					cellular_component											owl:Class	
GO:0033606	biolink:NamedThing	chemokine receptor transport within lipid bilayer	The directed movement of a chemokine receptor within a lipid bilayer.	tmpzr1t_l9r_go_relaxed.owl	chemokine receptor translocation within membrane													biological_process											owl:Class	
GO:0003944	biolink:NamedThing	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase activity	Catalysis of the reaction: glycoprotein N-acetyl-D-glucosaminyl-phospho-D-mannose + H2O = N-acetyl-D-glucosamine + glycoprotein phospho-D-mannose.	tmpzr1t_l9r_go_relaxed.owl	glycoprotein-N-acetyl-D-glucosaminyl-phospho-D-mannose N-acetyl-D-glucosaminylphosphohydrolase activity|alpha-N-acetyl-D-glucosamine-1-phosphodiester N-acetylglucosaminidase activity|phosphodiester glycosidase activity|alpha-N-acetylglucosaminyl phosphodiesterase activity|2-acetamido-2-deoxy-alpha-D-glucose 1-phosphodiester acetamidodeoxyglucohydrolase activity|lysosomal alpha-N-acetylglucosaminidase activity				EC:3.1.4.45|MetaCyc:3.1.4.45-RXN|RHEA:24372									molecular_function											owl:Class	
GO:0046421	biolink:NamedThing	methylisocitrate lyase activity	Catalysis of the reaction: (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate = pyruvate + succinate.	tmpzr1t_l9r_go_relaxed.owl	(2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate pyruvate-lyase (succinate-forming)|(2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate pyruvate-lyase activity|2-methylisocitrate lyase activity|MICL				EC:4.1.3.30|KEGG_REACTION:R00409|RHEA:16809|MetaCyc:METHYLISOCITRATE-LYASE-RXN									molecular_function											owl:Class	
GO:0009509	biolink:NamedThing	chromoplast	A plastid containing pigments other than chlorophyll, usually yellow and orange carotenoid pigments.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Chromoplast									cellular_component											owl:Class	
GO:0018483	biolink:NamedThing	6-oxohexanoate dehydrogenase activity	Catalysis of the reaction: 6-oxohexanoate + NADP+ + H2O = adipate + NADPH + H+.	tmpzr1t_l9r_go_relaxed.owl	6-oxohexanoate:NADP+ oxidoreductase activity				MetaCyc:6-OXOHEXANOATE-OXIDATION-RXN|EC:1.2.1.63|UM-BBD_reactionID:r0175|RHEA:13397									molecular_function											owl:Class	
GO:0097167	biolink:NamedThing	circadian regulation of translation	Any process that modulates the frequency, rate or extent of mRNA translation with a regularity of approximately 24 hours.	tmpzr1t_l9r_go_relaxed.owl	regulation of mRNA translation in response to circadian clock							pr	2011-09-29T03:13:31Z					biological_process											owl:Class	
GO:0102955	biolink:NamedThing	S-adenosylmethionine:2-demethylmenaquinol-7 methyltransferase activity	Catalysis of the reaction: 2-demethylmenaquinol-7 + S-adenosyl-L-methionine  = menaquinol-7 + S-adenosyl-L-homocysteine  + H+.	tmpzr1t_l9r_go_relaxed.owl					EC:2.1.1.163|RHEA:33255|MetaCyc:RXN-9191									molecular_function											owl:Class	
GO:0010247	biolink:NamedThing	detection of phosphate ion	The series of events in which a phosphate ion stimulus is received by a cell and converted into a molecular signal.	tmpzr1t_l9r_go_relaxed.owl	phosphate ion perception|phosphate ion sensing|phosphate ion detection													biological_process											owl:Class	
GO:1901382	biolink:NamedThing	regulation of chorionic trophoblast cell proliferation	Any process that modulates the frequency, rate or extent of chorionic trophoblast cell proliferation.	tmpzr1t_l9r_go_relaxed.owl								vk	2012-10-01T10:03:13Z					biological_process											owl:Class	
GO:0043221	biolink:NamedThing	SMC family protein binding	Binding to a protein from the structural maintenance of chromosomes (SMC) family, a group of chromosomal ATPases with a role in mitotic chromosome organization.	tmpzr1t_l9r_go_relaxed.owl	structural maintenance of chromosomes family protein binding													molecular_function											owl:Class	
GO:0034450	biolink:NamedThing	ubiquitin-ubiquitin ligase activity	Isoenergetic transfer of ubiquitin from one protein to an existing ubiquitin chain via the reaction X-ubiquitin + Y-ubiquitin -> Y-ubiquitin-ubiquitin + X, where both the X-ubiquitin and Y-ubiquitin-ubiquitin linkages are thioester bonds between the C-terminal glycine of ubiquitin and a sulfhydryl side group of a cysteine residue.	tmpzr1t_l9r_go_relaxed.owl	E4				Reactome:R-HSA-975122|Reactome:R-HSA-937050									molecular_function											owl:Class	
GO:0085026	biolink:NamedThing	tubovesicular membrane network	A complex, symbiont-induced host-derived organelle that is comprised of multiple protein and lipid domains.	tmpzr1t_l9r_go_relaxed.owl	TVM network|TVN							jl	2010-07-09T03:55:41Z					cellular_component											owl:Class	
GO:0004507	biolink:NamedThing	steroid 11-beta-monooxygenase activity	Catalysis of the reaction: a steroid + reduced adrenal ferredoxin + O2 = an 11-beta-hydroxysteroid + oxidized adrenal ferredoxin + H2O.	tmpzr1t_l9r_go_relaxed.owl	cytochrome p450 XIB1 activity|steroid 11beta-monooxygenase activity|steroid,reduced-adrenal-ferredoxin:oxygen oxidoreductase (11beta-hydroxylating)|cytochrome P450 CYP11B1|steroid 11beta/18-hydroxylase activity|steroid 11-beta-hydroxylase activity|cytochrome P450 CYP11B2|steroid 11-beta/18-hydroxylase activity|steroid 11beta-hydroxylase activity|oxygenase, steroid 11beta -mono-				Reactome:R-HSA-194017|EC:1.14.15.4|RHEA:15629|Reactome:R-HSA-5600598|Reactome:R-HSA-193997|Reactome:R-HSA-5580292|MetaCyc:STEROID-11-BETA-MONOOXYGENASE-RXN									molecular_function											owl:Class	
GO:0021956	biolink:NamedThing	central nervous system interneuron axonogenesis	Generation of a long process that carries efferent (outgoing) action potentials from the cell body towards target cells from a neuron located in the central nervous system whose axons remain within a single brain region.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0047297	biolink:NamedThing	asparagine-oxo-acid transaminase activity	Catalysis of the reaction: a 2-oxo acid + L-asparagine = an amino acid + 2-oxosuccinamate.	tmpzr1t_l9r_go_relaxed.owl	asparagine--oxo-acid aminotransferase activity|asparagine-oxo-acid aminotransferase activity|asparagine-keto acid aminotransferase activity|L-asparagine:2-oxo-acid aminotransferase activity				MetaCyc:2.6.1.14-RXN|EC:2.6.1.14|RHEA:19813									molecular_function											owl:Class	
GO:0050391	biolink:NamedThing	valine dehydrogenase (NADP) activity	Catalysis of the reaction: L-valine + H2O + NADP+ = 3-methyl-2-oxobutanoate + NH3 + NADPH.	tmpzr1t_l9r_go_relaxed.owl	valine dehydrogenase (nicotinanide adenine dinucleotide phosphate)|L-valine:NADP+ oxidoreductase (deaminating)|valine dehydrogenase (NADP+) activity				EC:1.4.1.8|MetaCyc:VALINE-DEHYDROGENASE-NADP+-RXN|RHEA:11156									molecular_function											owl:Class	
GO:0071453	biolink:NamedThing	cellular response to oxygen levels	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of oxygen.	tmpzr1t_l9r_go_relaxed.owl	cellular response to oxygen							mah	2009-12-16T04:43:59Z					biological_process											owl:Class	
GO:1990375	biolink:NamedThing	baculum development	The reproductive developmental process whose specific outcome is the progression of the baculum over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl	penile bone development|os penis development|penis bone development							sl	2014-05-01T23:59:13Z					biological_process											owl:Class	
GO:0010575	biolink:NamedThing	positive regulation of vascular endothelial growth factor production	Any process that increases or activates the frequency, rate, or extent of production of vascular endothelial growth factor.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0098620	biolink:NamedThing	seryl-selenocysteinyl-tRNA kinase activity	Catalysis of the reaction: Ser-tRNA(Sec) + ATP = Sep-tRNA(Sec) + ADP.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-2408507									molecular_function											owl:Class	
GO:0047910	biolink:NamedThing	galactose 1-dehydrogenase (NADP+) activity	Catalysis of the reaction: D-galactose + NADP+ = D-galactonolactone + NADPH.	tmpzr1t_l9r_go_relaxed.owl	D-galactose dehydrogenase (NADP+)|D-galactose:NADP+ 1-oxidoreductase activity				MetaCyc:GALACTOSE-1-DEHYDROGENASE-NADP+-RXN|EC:1.1.1.120|RHEA:18625									molecular_function											owl:Class	
GO:0043716	biolink:NamedThing	2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase activity	Catalysis of the reaction: 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate + H2O = 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + phosphate. 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate is also known as HK-MTPenyl-P, and 1,2-dihydroxy-3-keto-5-methylthiopentene as DHK-MTPene.	tmpzr1t_l9r_go_relaxed.owl	2-hydroxy-3-keto-5-methylthio-phosphopentene phosphatase activity|HK-MTPenyl-1-P phosphatase activity				RHEA:14481|KEGG_REACTION:R07394|MetaCyc:R83-RXN									molecular_function											owl:Class	
GO:1901387	biolink:NamedThing	positive regulation of voltage-gated calcium channel activity	Any process that activates or increases the frequency, rate or extent of voltage-gated calcium channel activity.	tmpzr1t_l9r_go_relaxed.owl	up regulation of dihydropyridine-sensitive calcium channel activity|activation of voltage-dependent calcium channel activity|activation of depolarization-activated voltage-gated calcium channel activity|up regulation of depolarization-activated voltage-gated calcium channel activity|up-regulation of voltage-dependent calcium channel activity|positive regulation of voltage-gated calcium ion channel activity|up-regulation of voltage-gated calcium ion channel activity|positive regulation of dihydropyridine-sensitive calcium channel activity|positive regulation of voltage-sensitive calcium channel|positive regulation of depolarization-activated voltage gated calcium channel activity|activation of dihydropyridine-sensitive calcium channel activity|positive regulation of depolarization-activated voltage-gated calcium channel|up regulation of depolarization-activated calcium channel|upregulation of voltage-gated calcium channel activity|up-regulation of voltage-sensitive calcium channel|activation of depolarization-activated calcium channel|up regulation of voltage-gated calcium channel activity|up regulation of depolarization-activated voltage gated calcium channel activity|positive regulation of voltage gated calcium channel activity|upregulation of voltage-sensitive calcium channel|up-regulation of voltage-gated calcium channel activity|activation of voltage-gated calcium channel activity|up-regulation of depolarization-activated voltage-gated calcium channel|positive regulation of depolarization-activated calcium channel|upregulation of voltage-gated calcium ion channel activity|up-regulation of depolarization-activated voltage gated calcium channel activity|up-regulation of depolarization-activated calcium channel|positive regulation of voltage-dependent calcium channel activity|activation of voltage-gated calcium ion channel activity|up regulation of voltage gated calcium channel activity|activation of voltage gated calcium channel activity|activation of voltage-sensitive calcium channel|up-regulation of dihydropyridine-sensitive calcium channel activity|up-regulation of voltage gated calcium channel activity|upregulation of voltage-dependent calcium channel activity|up regulation of voltage-gated calcium ion channel activity|up-regulation of depolarization-activated voltage-gated calcium channel activity|up regulation of voltage-sensitive calcium channel|up regulation of voltage-dependent calcium channel activity|upregulation of voltage gated calcium channel activity|upregulation of depolarization-activated voltage-gated calcium channel|upregulation of dihydropyridine-sensitive calcium channel activity|activation of depolarization-activated voltage-gated calcium channel|upregulation of depolarization-activated calcium channel|upregulation of depolarization-activated voltage-gated calcium channel activity|positive regulation of depolarization-activated voltage-gated calcium channel activity|upregulation of depolarization-activated voltage gated calcium channel activity|activation of depolarization-activated voltage gated calcium channel activity|up regulation of depolarization-activated voltage-gated calcium channel							vk	2012-10-01T10:35:32Z					biological_process											owl:Class	
GO:0019679	biolink:NamedThing	propionate metabolic process, methylcitrate cycle	The chemical reactions and pathways involving propionate that occur in the methylcitrate cycle.	tmpzr1t_l9r_go_relaxed.owl	propionate metabolism, methylcitrate cycle				MetaCyc:PWY0-42									biological_process											owl:Class	
GO:0086087	biolink:NamedThing	voltage-gated potassium channel activity involved in bundle of His cell action potential repolarization	Enables the transmembrane transfer of a potassium ion by a voltage-gated channel through the plasma membrane of a bundle of His cell contributing to the repolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.	tmpzr1t_l9r_go_relaxed.owl								dph	2011-11-22T01:30:20Z					molecular_function											owl:Class	
GO:0071473	biolink:NamedThing	cellular response to cation stress	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of cation stress, an increase or decrease in the concentration of positively charged ions in the environment.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-12-18T11:49:46Z					biological_process											owl:Class	
GO:1902752	biolink:NamedThing	regulation of renal amino acid absorption	Any process that modulates the frequency, rate or extent of renal amino acid absorption.	tmpzr1t_l9r_go_relaxed.owl								hjd	2014-03-05T15:43:55Z					biological_process											owl:Class	
GO:0035760	biolink:NamedThing	cytoplasmic polyadenylation-dependent rRNA catabolic process	The chemical reactions and pathways occurring in the cytoplasm and resulting in the breakdown of a ribosomal RNA (rRNA) molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target rRNA truncated degradation intermediate.	tmpzr1t_l9r_go_relaxed.owl	cytoplasmic poly(A)-dependent rRNA catabolic process							bf	2011-03-25T02:14:50Z					biological_process											owl:Class	
GO:0036078	biolink:NamedThing	minus-end specific microtubule depolymerization	The removal of tubulin heterodimers from the minus end of a microtubule.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-12-19T03:20:25Z					biological_process											owl:Class	
GO:0019056	biolink:NamedThing	modulation by virus of host transcription	Any process in which a virus modulates the frequency, rate or extent of its host's transcription.	tmpzr1t_l9r_go_relaxed.owl	viral perturbation of host cell transcription|modification by virus of host transcription													biological_process											owl:Class	
GO:0001988	biolink:NamedThing	positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure	Any process that activates, maintains or increases the frequency, rate or extent of heart contraction as a result of the baroreceptor response to decreased blood pressure.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of heart contraction rate in baroreceptor response to decreased blood pressure|positive regulation of cardiac contraction rate in baroreceptor response to decreased blood pressure|stimulation of heart contraction rate in baroreceptor response to decreased blood pressure|upregulation of heart contraction rate in baroreceptor response to decreased blood pressure|activation of heart contraction rate in baroreceptor response to decreased blood pressure|positive control of heart contraction rate in baroreceptor response to decreased blood pressure|positive regulation of heart contraction rate in baroreceptor response to decreased blood pressure|up regulation of heart contraction rate in baroreceptor response to decreased blood pressure													biological_process											owl:Class	
GO:0046313	biolink:NamedThing	phosphoarginine catabolic process	The chemical reactions and pathways resulting in the breakdown of phosphoarginine, a phosphorylated derivative of the amino acid arginine.	tmpzr1t_l9r_go_relaxed.owl	phosphoarginine breakdown|phosphoarginine catabolism|phosphoarginine degradation													biological_process											owl:Class	
GO:0031761	biolink:NamedThing	fMet-Leu-Phe receptor binding	Binding to a fMet-Leu-Phe receptor.	tmpzr1t_l9r_go_relaxed.owl	fMet-Leu-Phe receptor ligand|N-formyl peptide receptor binding													molecular_function											owl:Class	
GO:0006189	biolink:NamedThing	'de novo' IMP biosynthetic process	The chemical reactions and pathways resulting in the formation of IMP, inosine monophosphate, by the stepwise assembly of a purine ring on ribose 5-phosphate.	tmpzr1t_l9r_go_relaxed.owl	'de novo' purine biosynthetic process|'de novo' IMP biosynthesis|'de novo' purine biosynthesis|'de novo' IMP anabolism|'de novo' IMP synthesis|'de novo' IMP formation													biological_process											owl:Class	
GO:1904116	biolink:NamedThing	response to vasopressin	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vasopressin stimulus.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-04-06T19:39:42Z					biological_process											owl:Class	
GO:0044795	biolink:NamedThing	trans-Golgi network to recycling endosome transport	The directed movement of substances, in membrane-bounded vesicles, from the trans-Golgi network to the recycling endosomes.	tmpzr1t_l9r_go_relaxed.owl								jl	2013-08-27T16:04:00Z					biological_process											owl:Class	
GO:0036400	biolink:NamedThing	short neuropeptide F receptor activity	Combining with a short neuropeptide F and transmitting the signal within the cell to initiate a change in cell activity. Short neuropeptide F is an arthropod peptide of less than 28 residues (as small as 8-10 residues in some species) with a C-terminal RFamide or LRFamide.	tmpzr1t_l9r_go_relaxed.owl	sNPF receptor activity					Despite their naming, neuropeptide F (NPF) and short neuropeptide F (sNPF) are not closely related.		bf	2013-07-18T14:46:40Z					molecular_function											owl:Class	
GO:0071279	biolink:NamedThing	cellular response to cobalt ion	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cobalt ion stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-12-10T03:55:55Z					biological_process											owl:Class	
GO:0032025	biolink:NamedThing	response to cobalt ion	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cobalt ion stimulus.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0019444	biolink:NamedThing	tryptophan catabolic process to catechol	The chemical reactions and pathways resulting in the breakdown of tryptophan into other compounds, including catechol.	tmpzr1t_l9r_go_relaxed.owl	tryptophan degradation to catechol|tryptophan breakdown to catechol				MetaCyc:TRPCAT-PWY									biological_process											owl:Class	
GO:0050545	biolink:NamedThing	sulfopyruvate decarboxylase activity	Catalysis of the reaction: 3-sulfopyruvate + H(+) = CO(2) + sulfoacetaldehyde.	tmpzr1t_l9r_go_relaxed.owl	sulfopyruvate carboxy-lyase activity|sulfopyruvate carboxy-lyase (2-sulfoacetaldehyde-forming)|sulphopyruvate decarboxylase activity				RHEA:20948|MetaCyc:R231-RXN|EC:4.1.1.79|KEGG_REACTION:R05774									molecular_function											owl:Class	
GO:0039686	biolink:NamedThing	bidirectional double-stranded viral DNA replication	A viral DNA replication process where replication occurs in both directions from the starting point. This creates two replication forks, moving in opposite directions.	tmpzr1t_l9r_go_relaxed.owl	viral bidirectional dsDNA replication				VZ:1939			bf	2013-10-17T14:42:09Z					biological_process											owl:Class	
GO:0019979	biolink:NamedThing	interleukin-4 binding	Binding to interleukin-4.	tmpzr1t_l9r_go_relaxed.owl	IL-4 binding													molecular_function											owl:Class	
GO:0018599	biolink:NamedThing	2-hydroxyisobutyrate 3-monooxygenase activity	Catalysis of the reaction: 2-hydroxyisobutyrate + 1/2 O2 = 2,3-dihydroxy-2-methyl propionate.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0619									molecular_function											owl:Class	
GO:0050488	biolink:NamedThing	ecdysteroid UDP-glucosyltransferase activity	Catalysis of the reaction: UDP-glucose + ecdysteroid = UDP + glucosyl-ecdysteroid.	tmpzr1t_l9r_go_relaxed.owl	ecdysteroid UDP-glucosyl/UDP-glucuronosyl transferase activity											GO:0050489		molecular_function											owl:Class	
GO:0102332	biolink:NamedThing	fatty-acyl-[acp] elongase/decarboxylase activity	Catalysis of the reaction: malonyl-CoA + H+ + a long-chain acyl-[acp] + a reduced electron acceptor = 2 carbon dioxide + coenzyme A + a terminal olefin + a holo-[acyl-carrier protein] + an oxidized electron acceptor.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-13260									molecular_function											owl:Class	
GO:0042349	biolink:NamedThing	guiding stereospecific synthesis activity	The orientation of free radical substrates in such a way that only a particular stereoisomer is synthesized by an enzyme. Best characterized as a function during lignan biosynthesis.	tmpzr1t_l9r_go_relaxed.owl	dirigent protein													molecular_function											owl:Class	
GO:0021556	biolink:NamedThing	central nervous system formation	The process that gives rise to the central nervous system. This process pertains to the initial formation of a structure from unspecified parts. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain, spinal cord and spinal nerves. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0099557	biolink:NamedThing	trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission	Cell-cell signaling between presynapse and postsynapse, mediated by transynaptic protein complexes, that modulates the synaptic transmission properties of the synapse.	tmpzr1t_l9r_go_relaxed.owl						Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.								biological_process											owl:Class	
GO:0061109	biolink:NamedThing	dense core granule organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a dense core granule. A dense core granule is a secretory organelle found in endocrine cells.	tmpzr1t_l9r_go_relaxed.owl	dense core granule organisation							dph	2010-05-01T09:34:37Z					biological_process											owl:Class	
GO:0042383	biolink:NamedThing	sarcolemma	The outer membrane of a muscle cell, consisting of the plasma membrane, a covering basement membrane (about 100 nm thick and sometimes common to more than one fiber), and the associated loose network of collagen fibers.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Sarcolemma									cellular_component											owl:Class	
GO:0048075	biolink:NamedThing	positive regulation of eye pigmentation	Any process that activates or increases the frequency, rate or extent of establishment of a pattern of pigment in the eye of an organism.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of eye pigmentation|up regulation of eye pigmentation|activation of eye pigmentation|upregulation of eye pigmentation|stimulation of eye pigmentation													biological_process											owl:Class	
GO:0042078	biolink:NamedThing	germ-line stem cell division	The self-renewing division of a germline stem cell to produce a daughter stem cell and a daughter germ cell, which will divide to form the gametes.	tmpzr1t_l9r_go_relaxed.owl	germ-line stem cell renewal											GO:0048131		biological_process											owl:Class	
GO:0018753	biolink:NamedThing	cyanuric acid amidohydrolase activity	Catalysis of the reaction: cyanuric acid + H2O = biuret + CO2.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0116|MetaCyc:R468-RXN|RHEA:14641|EC:3.5.2.15									molecular_function											owl:Class	
GO:0043770	biolink:NamedThing	demethylmenaquinone methyltransferase activity	Catalysis of the reaction: 2-demethylmenaquinone + S-adenosyl-L-methionine = menaquinone + S-adenosyl-L-homocysteine.	tmpzr1t_l9r_go_relaxed.owl					EC:2.1.1.163									molecular_function											owl:Class	
GO:0047379	biolink:NamedThing	ADP-dependent short-chain-acyl-CoA hydrolase activity	Catalysis of the reaction: H2O + a short-chain acyl-CoA = a short-chain carboxylate + CoA.	tmpzr1t_l9r_go_relaxed.owl	ADP-dependent propionyl coenzyme A hydrolase activity|ADP-dependent short-chain acyl-CoA thioesterase activity|ADP-dependent propionyl-CoA hydrolase activity|ADP-dependent short-chain acyl-CoA hydrolase activity|ADP-dependent short-chain acyl coenzyme A hydrolase activity|ADP-dependent propionyl-CoA thioesterase activity|ADP-dependent-short-chain-acyl-CoA hydrolase activity				EC:3.1.2.18|MetaCyc:3.1.2.18-RXN									molecular_function											owl:Class	
GO:0097407	biolink:NamedThing	Bunina body	Small granular inclusions (about 1-3 microns in diameter) found in the anterior horn cells, and appearing either singly or in a group. Sometimes they are arranged in small beaded chains. Bunina bodies express cystatin C and consist of electron-dense amorphous material that contains tubules or vesicular structures. The amorphous material frequently includes a cytoplasmic island containing neurofilaments and other micro-organelles.	tmpzr1t_l9r_go_relaxed.owl					NIF_Subcellular:nlx_subcell_20090101			pr	2012-10-31T13:52:30Z					cellular_component											owl:Class	
GO:0062206	biolink:NamedThing	manoyl oxide synthase activity	Catalysis of the reaction: 8-hydroxycopalyl diphosphate = (13R)-manoyl oxide + diphosphate.	tmpzr1t_l9r_go_relaxed.owl					EC:4.2.3.190|RHEA:54516			dph	2020-01-03T14:48:52Z					molecular_function											owl:Class	
GO:0000805	biolink:NamedThing	X chromosome	The sex chromosome present in both sexes of species in which the male is the heterogametic sex. Two copies of the X chromosome are present in each somatic cell of females and one copy is present in males.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:X_chromosome									cellular_component											owl:Class	
GO:0003101	biolink:NamedThing	regulation of systemic arterial blood pressure by circulatory epinephrine-norepinephrine	The process in which epinephrine-norepinephrine modulate the force with which blood passes through the circulatory system.	tmpzr1t_l9r_go_relaxed.owl	regulation of blood pressure by circulating adrenaline-noradrenaline													biological_process											owl:Class	
GO:0047706	biolink:NamedThing	biochanin-A reductase activity	Catalysis of the reaction: dihydrobiochanin A + NADP(+) = biochanin A + H(+) + NADPH.	tmpzr1t_l9r_go_relaxed.owl	dihydrobiochanin-A:NADP+ delta2-oxidoreductase activity				RHEA:12817|KEGG_REACTION:R02954|EC:1.3.1.46|MetaCyc:BIOCHANIN-A-REDUCTASE-RXN									molecular_function											owl:Class	
GO:0106238	biolink:NamedThing	peregrinol diphosphate synthase activity	Catalysis of the reaction:peregrinol diphosphate = all-trans-geranylgeranyl diphosphate + H2O.	tmpzr1t_l9r_go_relaxed.owl					EC:4.2.1.174|RHEA:54652			hjd	2019-12-19T15:28:28Z					molecular_function											owl:Class	
GO:0060586	biolink:NamedThing	multicellular organismal iron ion homeostasis	Any process involved in the maintenance of the distribution of iron stores within tissues and organs of a multicellular organism.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-05-08T02:18:21Z					biological_process											owl:Class	
GO:0015657	biolink:NamedThing	branched-chain amino acid:sodium symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: branched-chain amino acid(out) + cation(out) = branched-chain amino acid(in) + cation(in).	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0033454	biolink:NamedThing	GCC codon-amino acid adaptor activity	A triplet codon-amino acid adaptor activity that recognizes a GCC codon.	tmpzr1t_l9r_go_relaxed.owl	alanine tRNA					Note that in the standard genetic code, GCC codes for alanine.								molecular_function											owl:Class	
GO:0010188	biolink:NamedThing	response to microbial phytotoxin	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a microbial phytotoxin stimulus. A microbial phytotoxin is a chemical substance produced by microbes which is toxic to plants.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0021650	biolink:NamedThing	vestibulocochlear nerve formation	The process that gives rise to the vestibulocochlear nerve. This process pertains to the initial formation of a structure from unspecified parts. This sensory nerve innervates the membranous labyrinth of the inner ear. The vestibular branch innervates the vestibular apparatus that senses head position changes relative to gravity. The auditory branch innervates the cochlear duct, which is connected to the three bony ossicles which transduce sound waves into fluid movement in the cochlea.	tmpzr1t_l9r_go_relaxed.owl	CN VII formation													biological_process											owl:Class	
GO:1990509	biolink:NamedThing	PYM-mago-Y14 complex	Protein complex involved in the disassembly of Mago-Y14 from the spliced mRNA during first round of translation, independently of the translational machinery. Conserved from fission yeast to humans.	tmpzr1t_l9r_go_relaxed.owl	PYM-mago-RNA-binding protein 8A complex|wibg-mago-tsu complex					An example of this is wibg in Drosophila melanogaster (P82804) in PMID:14968132 (inferred from physical interaction).		bhm	2014-10-03T12:52:01Z					cellular_component											owl:Class	
GO:1900082	biolink:NamedThing	negative regulation of arginine catabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of arginine catabolic process.	tmpzr1t_l9r_go_relaxed.owl	down regulation of arginine breakdown|down-regulation of arginine catabolic process|downregulation of arginine degradation|down-regulation of arginine degradation|inhibition of arginine degradation|downregulation of arginine catabolic process|downregulation of arginine breakdown|inhibition of arginine catabolic process|negative regulation of arginine catabolism|inhibition of arginine catabolism|down regulation of arginine degradation|negative regulation of arginine breakdown|inhibition of arginine breakdown|down regulation of arginine catabolism|negative regulation of arginine degradation|down-regulation of arginine breakdown|down-regulation of arginine catabolism|down regulation of arginine catabolic process|downregulation of arginine catabolism							pr	2012-02-01T04:04:45Z					biological_process											owl:Class	
GO:0070066	biolink:NamedThing	cellubrevin-VAMP4-endobrevin-syntaxin-6 complex	A SNARE complex that contains cellubrevin (VAMP3), VAMP4, endobrevin (VAMP8), and syntaxin 6 (or orthologs thereof).	tmpzr1t_l9r_go_relaxed.owl	SNARE complex (Vamp3, Vamp4, Vam8, Stx6)|Vamp3-Vamp4-Vam8-Stx6 complex													cellular_component											owl:Class	
GO:0061782	biolink:NamedThing	vesicle fusion with vesicle	Fusion of the membrane of a transport vesicle with a target membrane on another vesicle.	tmpzr1t_l9r_go_relaxed.owl	vesicle-vesicle fusion|vesicle to vesicle fusion							dph	2016-09-06T13:29:49Z					biological_process											owl:Class	
GO:0071254	biolink:NamedThing	cytoplasmic U snRNP body	A ribonucleoprotein complex that can be visualized as a focus in the cytoplasm, and contains uridine-rich small nuclear ribonucleoproteins (U snRNPs) and essential snRNP assembly factors. These U bodies are invariably found in association with P bodies.	tmpzr1t_l9r_go_relaxed.owl	U body|U-body							mah	2009-12-04T10:31:29Z					cellular_component											owl:Class	
GO:0051218	biolink:NamedThing	tungsten incorporation via L-selenocysteinyl tungsten bis(molybdopterin guanine dinucleotide)	The incorporation of tungsten into a protein via L-selenocysteinyl tungsten bis(molybdopterin guanine dinucleotide).	tmpzr1t_l9r_go_relaxed.owl					RESID:AA02376									biological_process											owl:Class	
GO:0089706	biolink:NamedThing	L-ornithine transmembrane export from vacuole	The directed movement of L-ornithine out of the vacuole, across the vacuolar membrane.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1901970	biolink:NamedThing	positive regulation of mitotic sister chromatid separation	Any process that activates or increases the frequency, rate or extent of mitotic sister chromatid separation.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of chromosome separation during mitosis|activation of chromosome separation during mitosis|positive regulation of mitotic chromosome separation|up regulation of mitotic sister chromatid separation|positive regulation of sister chromatid separation during mitosis|up regulation of mitotic chromosome separation|activation of mitotic sister chromatid separation|upregulation of mitotic chromosome separation|up-regulation of chromosome separation during mitosis|upregulation of sister chromatid separation during mitosis|up regulation of sister chromatid separation during mitosis|activation of sister chromatid separation during mitosis|up-regulation of sister chromatid separation during mitosis|up-regulation of mitotic sister chromatid separation|upregulation of mitotic sister chromatid separation|activation of mitotic sister chromatid resolution|positive regulation of mitotic sister chromatid resolution|up-regulation of mitotic sister chromatid resolution|upregulation of chromosome separation during mitosis|up regulation of mitotic sister chromatid resolution|up-regulation of mitotic chromosome separation|upregulation of mitotic sister chromatid resolution|activation of mitotic chromosome separation|up regulation of chromosome separation during mitosis							al	2013-02-22T19:06:19Z					biological_process											owl:Class	
GO:0031534	biolink:NamedThing	minus-end directed microtubule sliding	The movement of one microtubule along another microtubule, where the motion is directed towards the minus ends of the microtubules.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0051012	biolink:NamedThing	microtubule sliding	The movement of one microtubule along another microtubule.	tmpzr1t_l9r_go_relaxed.owl	microtubule translocation													biological_process											owl:Class	
GO:1990934	biolink:NamedThing	nucleolus-like body	A nuclear compartment containing significant amounts of non-nucleolar, spliceosomal components. It is commonly found in germinal vesicle (GV) stage oocytes, and is similar to both nucleoli and sphere organelles.	tmpzr1t_l9r_go_relaxed.owl	NLB|compact nucleolus							sl	2016-03-21T21:28:14Z					cellular_component											owl:Class	
GO:0016761	biolink:NamedThing	cellulose synthase (GDP-forming) activity	Catalysis of the reaction: GDP-glucose + ((1,4)-beta-D-glucosyl)(n) = GDP + ((1,4)-beta-D-glucosyl)(n+1).	tmpzr1t_l9r_go_relaxed.owl	GDPglucose:1,4-beta-D-glucan 4-beta-D-glucosyltransferase activity|cellulose synthase (guanosine diphosphate-forming) activity|guanosine diphosphoglucose-1,4-beta-glucan glucosyltransferase activity|GDP-glucose-cellulose glucosyltransferase activity|GDP-glucose:1,4-beta-D-glucan 4-beta-D-glucosyltransferase activity|GDP-glucose-beta-D-glucan glucosyltransferase activity|guanosine diphosphoglucose-cellulose glucosyltransferase activity				EC:2.4.1.29|MetaCyc:CELLULOSE-SYNTHASE-GDP-FORMING-RXN|RHEA:17797									molecular_function											owl:Class	
GO:0016759	biolink:NamedThing	cellulose synthase activity	Catalysis of the reaction: nucleoside-disphosphate-glucose + ((1,4)-beta-D-glucosyl)(n) = nucleoside-disphosphate + ((1,4)-beta-D-glucosyl)(n+1).	tmpzr1t_l9r_go_relaxed.owl	cellulose synthetase activity													molecular_function											owl:Class	
GO:1990889	biolink:NamedThing	H4K20me3 modified histone binding	Binding to a histone H4 in which the lysine residue at position 20 has been modified by trimethylation.	tmpzr1t_l9r_go_relaxed.owl								al	2015-10-30T15:43:09Z					molecular_function											owl:Class	
GO:0001002	biolink:NamedThing	RNA polymerase III type 1 promoter sequence-specific DNA binding	Binding to a sequence of DNA that is a part of a type 1 promoter that controls transcription by RNA polymerase III. Type 1 promoters are found in 5S rRNA genes, downstream of the transcription start site within the sequence of the mature RNA, and require TFIIIA for recognition.	tmpzr1t_l9r_go_relaxed.owl	RNA polymerase III type 1 promoter DNA binding							krc	2010-08-18T05:38:20Z			GO:0001030		molecular_function											owl:Class	
GO:0009366	biolink:NamedThing	enterobactin synthetase complex	A multienzyme complex usually composed of four proteins, EntB, EntD, EntE and EntF. Plays a role in the enterobactin biosynthesis pathway.	tmpzr1t_l9r_go_relaxed.owl	enterochelin synthetase complex				MetaCyc:ENTMULTI-CPLX									cellular_component											owl:Class	
GO:0061030	biolink:NamedThing	epithelial cell differentiation involved in mammary gland alveolus development	The process in which a relatively unspecialized epithelial cell becomes a more specialized epithelial cell of the mammary gland alveolus.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-02-09T09:43:00Z					biological_process											owl:Class	
GO:0001162	biolink:NamedThing	RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding	Binding to an RNA polymerase II intronic DNA sequence that regulates the transcription of the transcript it is contained within.	tmpzr1t_l9r_go_relaxed.owl						To minimize ambiguity in the use of the word "promoter" in GO, we have chosen the phrase "transcription regulatory region" to refer to all of the regulatory regions. Regulatory regions in the DNA which control initiation may include the "core promoter" where the basal transcription machinery binds, the "core promoter proximal region" where regulatory factors other than the basal machinery bind. There are also additional regulatory regions, in both the DNA and the RNA transcript, which regulate elongation or termination of transcription.		krc	2011-01-28T03:46:19Z					molecular_function											owl:Class	
GO:1901899	biolink:NamedThing	positive regulation of relaxation of cardiac muscle	Any process that activates or increases the frequency, rate or extent of relaxation of cardiac muscle.	tmpzr1t_l9r_go_relaxed.owl	upregulation of relaxation of cardiac muscle|up regulation of relaxation of cardiac muscle|up-regulation of relaxation of cardiac muscle|activation of relaxation of cardiac muscle							rl	2013-02-06T21:27:07Z					biological_process											owl:Class	
GO:1904844	biolink:NamedThing	response to L-glutamine	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-glutamine stimulus.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-12-07T19:39:17Z					biological_process											owl:Class	
GO:0060404	biolink:NamedThing	axonemal microtubule depolymerization	The removal of tubulin heterodimers from one or both ends of an axonemal microtubule. An axonemal microtubule is a microtubule in the axoneme of a cilium or flagellum; an axoneme contains nine modified doublet microtubules surrounding a pair of single microtubules.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1990029	biolink:NamedThing	vasomotion	The rhythmical contraction and relaxation of arterioles, observed as slow and fast waves, with frequencies of 1-2 and 10-20 cpm.	tmpzr1t_l9r_go_relaxed.owl								tb	2013-02-06T22:30:21Z					biological_process											owl:Class	
GO:0034534	biolink:NamedThing	1-methylnaphthalene hydroxylase activity	Catalysis of the reaction: 1-methylnaphthalene + NADH + H+ + O2 = 1-hydroxymethylnaphthalene + NAD+ + H2O.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0795|EC:1.14.13.-									molecular_function											owl:Class	
GO:0018454	biolink:NamedThing	acetoacetyl-CoA reductase activity	Catalysis of the reaction: (R)-3-hydroxyacyl-CoA + NADP+ = 3-oxoacyl-CoA + NADPH + H+.	tmpzr1t_l9r_go_relaxed.owl	D-3-hydroxyacyl-CoA reductase activity|(R)-3-hydroxyacyl-CoA dehydrogenase activity|short chain beta-ketoacetyl(acetoacetyl)-CoA reductase activity|beta-ketoacyl-CoA reductase|(R)-3-hydroxyacyl-CoA:NADP+ oxidoreductase activity|acetoacetyl coenzyme A reductase activity|D(-)-beta-hydroxybutyryl CoA-NADP oxidoreductase activity|hydroxyacyl coenzyme-A dehydrogenase activity|NADPH:acetoacetyl-CoA reductase activity|NADP-linked acetoacetyl CoA reductase activity				RHEA:22256|MetaCyc:RXN-7698|EC:1.1.1.36|UM-BBD_reactionID:r0202									molecular_function											owl:Class	
GO:0002316	biolink:NamedThing	follicular B cell differentiation	The process in which a B cell in the spleen acquires the specialized features of a follicular B cell. Follicular B cells are major population of mature recirculating B cells in the spleen and are located in the B-cell follicle region.	tmpzr1t_l9r_go_relaxed.owl	follicular B lymphocyte differentiation|follicular B-lymphocyte differentiation|follicular B cell development|follicular B-cell differentiation					Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.								biological_process											owl:Class	
GO:0043196	biolink:NamedThing	varicosity	Non-terminal inflated portion of the axon, containing the specialized apparatus necessary to release neurotransmitters.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0043079	biolink:NamedThing	antipodal cell nucleus	The nucleus of an antipodal cell, one of three cells of the embryo sac in angiosperms, found at the chalazal end of the embryo away from the point of entry of the pollen tube, and its descendents.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0099110	biolink:NamedThing	microtubule polymerization based protein transport to cell tip cortex	The transport of a protein to the cortex of the cell tip, driven by polymerization of a microtubule to which the protein is attached.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0047724	biolink:NamedThing	inosine nucleosidase activity	Catalysis of the reaction: inosine + H2O = D-ribose + hypoxanthine.	tmpzr1t_l9r_go_relaxed.owl	inosine-guanosine nucleosidase activity|inosinase activity|inosine ribohydrolase activity				EC:3.2.2.2|RHEA:16657|MetaCyc:INOSINE-NUCLEOSIDASE-RXN									molecular_function											owl:Class	
GO:1901859	biolink:NamedThing	negative regulation of mitochondrial DNA metabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrial DNA metabolic process.	tmpzr1t_l9r_go_relaxed.owl	inhibition of mtDNA metabolism|downregulation of mitochondrial DNA metabolism|inhibition of mtDNA metabolic process|down-regulation of mitochondrial DNA metabolic process|down-regulation of mtDNA metabolism|down regulation of mitochondrial DNA metabolic process|negative regulation of mtDNA metabolism|inhibition of mitochondrial DNA metabolism|down regulation of mtDNA metabolic process|inhibition of mitochondrial DNA metabolic process|down-regulation of mtDNA metabolic process|negative regulation of mtDNA metabolic process|down regulation of mitochondrial DNA metabolism|downregulation of mtDNA metabolic process|down-regulation of mitochondrial DNA metabolism|downregulation of mitochondrial DNA metabolic process|down regulation of mtDNA metabolism|downregulation of mtDNA metabolism|negative regulation of mitochondrial DNA metabolism							yaf	2013-02-01T10:05:09Z					biological_process											owl:Class	
GO:0052685	biolink:NamedThing	perillic acid-CoA ligase (ADP-forming) activity	Catalysis of the reaction: perillic acid + CoA-SH + ATP = H2O + ADP + phosphate + perillyl-CoA.	tmpzr1t_l9r_go_relaxed.owl	perillyl-CoA synthetase activity|perillic acid:CoA ligase (ADP-forming) activity				EC:6.2.1.-|KEGG_REACTION:R06367									molecular_function											owl:Class	
GO:1900679	biolink:NamedThing	negative regulation of ferricrocin biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of ferricrocin biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of ferricrocin synthesis|negative regulation of ferricrocin biosynthesis|downregulation of ferricrocin anabolism|downregulation of ferricrocin biosynthetic process|inhibition of ferricrocin synthesis|down-regulation of ferricrocin biosynthesis|downregulation of ferricrocin biosynthetic process, peptide formation|down-regulation of ferricrocin biosynthetic process|negative regulation of ferricrocin biosynthetic process, peptide formation|down-regulation of ferricrocin anabolism|down regulation of ferricrocin biosynthetic process, peptide modification|down regulation of ferricrocin synthesis|downregulation of ferricrocin synthesis|down regulation of ferricrocin biosynthetic process|negative regulation of ferricrocin biosynthetic process, peptide modification|negative regulation of ferricrocin anabolism|down regulation of ferricrocin formation|down-regulation of ferricrocin formation|down regulation of ferricrocin biosynthetic process, peptide formation|down regulation of ferricrocin anabolism|down regulation of ferricrocin biosynthesis|down-regulation of ferricrocin synthesis|inhibition of ferricrocin biosynthetic process, peptide modification|inhibition of ferricrocin formation|down-regulation of ferricrocin biosynthetic process, peptide formation|inhibition of ferricrocin anabolism|inhibition of ferricrocin biosynthesis|negative regulation of ferricrocin formation|downregulation of ferricrocin biosynthesis|downregulation of ferricrocin formation|inhibition of ferricrocin biosynthetic process|inhibition of ferricrocin biosynthetic process, peptide formation|down-regulation of ferricrocin biosynthetic process, peptide modification|downregulation of ferricrocin biosynthetic process, peptide modification							di	2012-05-22T04:28:15Z					biological_process											owl:Class	
GO:0007294	biolink:NamedThing	germarium-derived oocyte fate determination	The cell fate determination process in which a germarium-derived cell becomes capable of differentiating autonomously into an oocyte cell regardless of its environment; upon determination, the cell fate cannot be reversed. An example of this is found in Drosophila melanogaster.	tmpzr1t_l9r_go_relaxed.owl	maintenance of oocyte identity|oocyte cell fate determination											GO:0016350		biological_process											owl:Class	
GO:0050530	biolink:NamedThing	glucosylglycerol 3-phosphatase activity	Catalysis of the reaction: 2-O-(beta-D-glucosyl)-sn-glycerol 3-phosphate + H(2)O = 2-O-(beta-D-glucosyl)-sn-glycerol + phosphate.	tmpzr1t_l9r_go_relaxed.owl	2-(beta-D-glucosyl)-sn-glycerol-3-phosphate phosphohydrolase activity|StpA|salt tolerance protein A				MetaCyc:3.1.3.69-RXN|EC:3.1.3.69|RHEA:22652|KEGG_REACTION:R05791									molecular_function											owl:Class	
GO:0018386	biolink:NamedThing	N-terminal peptidyl-cysteine condensation with pyruvate to form N-pyruvic acid 2-iminyl-L-cysteine	The condensation of pyruvate through the 2-oxo group with the N-terminal cysteine of proteins to form the derivative N-pyruvic acid 2-iminyl-L-cysteine.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0274									biological_process											owl:Class	
GO:0103086	biolink:NamedThing	methylthiopentylmalate isomerase activity	Catalysis of the reaction: 2-(5'-methylthio)pentylmalate <=> 3-(5'-methylthio)pentylmalate.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXNQT-4170									molecular_function											owl:Class	
GO:1905947	biolink:NamedThing	positive regulation of response to calcium ion	Any process that activates or increases the frequency, rate or extent of response to calcium ion.	tmpzr1t_l9r_go_relaxed.owl	activation of response to Ca2+ ion|positive regulation of response to Ca2+ ion|activation of response to calcium ion|up regulation of response to Ca2+ ion|up-regulation of response to Ca2+ ion|upregulation of response to Ca2+ ion|up regulation of response to calcium ion|up-regulation of response to calcium ion|upregulation of response to calcium ion							bc	2017-02-13T10:56:49Z					biological_process											owl:Class	
GO:0039700	biolink:NamedThing	fusion of viral membrane with host outer nuclear membrane	Fusion of a viral primary envelope with the host outer nuclear membrane during nuclear egress. The transitory primary envelope is acquired by the virus as it buds at the inner nuclear membrane and gains access to the perinuclear space. This membrane is lost by fusing with the host outer nuclear membrane during nuclear exit.	tmpzr1t_l9r_go_relaxed.owl	fusion of viral membrane with host outer nuclear membrane involved in nuclear egress|viral primary envelope fusion with host outer nuclear membrane							bf	2013-11-06T15:07:46Z					biological_process											owl:Class	
GO:0061249	biolink:NamedThing	mesonephric glomerular capillary formation	The process that gives rise to a mesonephric glomerular capillary. This process pertains to the initial formation of a structure from unspecified parts.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-08-30T01:17:08Z					biological_process											owl:Class	
GO:0070670	biolink:NamedThing	response to interleukin-4	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-4 stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to IL-4							mah	2009-05-29T10:01:46Z					biological_process											owl:Class	
GO:0043874	biolink:NamedThing	acireductone synthase activity	Catalysis of the reactions: 5-(methylthio)-2,3-dioxopentyl phosphate + H2O = 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + phosphate; (1a) 5-(methylthio)-2,3-dioxopentyl phosphate = 2-hydroxy-5-(methylthio)-3-oxopent-1-enyl phosphate; (1b) 2-hydroxy-5-(methylthio)-3-oxopent-1-enyl phosphate + H2O = 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + phosphate.	tmpzr1t_l9r_go_relaxed.owl	E-1|5-(methylthio)-2,3-dioxopentyl-phosphate phosphohydrolase (isomerizing)|E-1 enolase-phosphatase				Reactome:R-HSA-1237129|EC:3.1.3.77|MetaCyc:3.1.3.77-RXN|RHEA:21700	This function is involved in the process of methionine salvage.								molecular_function											owl:Class	
GO:1903680	biolink:NamedThing	acinar cell of sebaceous gland differentiation	The process in which a relatively unspecialized cell acquires the specialized features of an acinar cell of sebaceous gland.	tmpzr1t_l9r_go_relaxed.owl	sebocyte differentiation							cls	2014-11-30T11:51:57Z					biological_process											owl:Class	
GO:1905298	biolink:NamedThing	regulation of intestinal epithelial cell development	Any process that modulates the frequency, rate or extent of intestinal epithelial cell development.	tmpzr1t_l9r_go_relaxed.owl								rph	2016-06-30T11:40:47Z					biological_process											owl:Class	
GO:0110142	biolink:NamedThing	ubiquinone biosynthesis complex	The cytosolic ubiquinone biosynthesis complex is composed of enzymes and accessory factors of the ubiquinone biosynthesis pathway and enables synthesis of the extremely hydrophobic molecule ubiquinone. In E. coli, the complex is composed of seven proteins: UbiE, F, G, H, I, J and K.	tmpzr1t_l9r_go_relaxed.owl	CoQ metabolon|Ubi complex							kmv	2019-04-25T15:48:21Z					cellular_component											owl:Class	
GO:0003948	biolink:NamedThing	N4-(beta-N-acetylglucosaminyl)-L-asparaginase activity	Catalysis of the reaction: N(4)-(beta-N-acetyl-D-glucosaminyl)-L-asparagine + H(2)O = N-acetyl-beta-D-glucosaminylamine + L-aspartate + H(+).	tmpzr1t_l9r_go_relaxed.owl	aspartylglucosaminidase activity|4-N-(beta-N-acetyl-D-glucosaminyl)-L-asparagine amidohydrolase activity|aspartylglucosylaminase activity|N4-(beta-N-acetyl-D-glucosaminyl)-L-asparagine amidohydrolase activity|glycosylasparaginase activity|aspartylglycosylamine amidohydrolase activity|N-aspartyl-beta-glucosaminidase activity|aspartylglucosylamine deaspartylase activity|aspartylglucosylaminidase activity|beta-aspartylglucosylamine amidohydrolase activity|glucosylamidase activity				KEGG_REACTION:R03421|EC:3.5.1.26|MetaCyc:3.5.1.26-RXN|RHEA:11544									molecular_function											owl:Class	
GO:0030743	biolink:NamedThing	rRNA (adenosine-2'-O-)-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing a single residue of 2'-O-methyladenosine.	tmpzr1t_l9r_go_relaxed.owl	rRNA adenosine 2'-methylase activity|S-adenosyl-L-methionine:rRNA (adenosine-2'-O)-methyltransferase activity|ribosomal ribonucleate adenosine 2'-methyltransferase activity|RNA-pentose methylase activity|thiostrepton-resistance methylase activity				RHEA:43212|EC:2.1.1.230|MetaCyc:2.1.1.66-RXN									molecular_function											owl:Class	
GO:0006640	biolink:NamedThing	monoacylglycerol biosynthetic process	The chemical reactions and pathways resulting in the formation of monoacylglycerol, any ester of glycerol in which any one of its hydroxyl groups has been acylated with a fatty acid, the other being non-esterified.	tmpzr1t_l9r_go_relaxed.owl	monoacylglycerol formation|monoglyceride biosynthesis|monoacylglycerol anabolism|monoacylglycerol synthesis|monoglyceride biosynthetic process|monoacylglycerol biosynthesis													biological_process											owl:Class	
GO:0060607	biolink:NamedThing	cell-cell adhesion involved in sealing an epithelial fold	The attachment of one cell to another cell along the edges of two epithelial folds, giving rise to the lumen of an epithelial tube.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-05-15T09:48:49Z					biological_process											owl:Class	
GO:0061476	biolink:NamedThing	response to anticoagulant	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an anticoagulant stimulus.	tmpzr1t_l9r_go_relaxed.owl								dph	2012-11-07T09:07:00Z					biological_process											owl:Class	
GO:0102404	biolink:NamedThing	linalyl 6-O-alpha-L-arabinopyranosyl-beta-D-glucopyranoside glucosidase (Yabukita) activity	Catalysis of the reaction: linalyl 6-O-alpha-L-arabinopyranosyl- beta-D-glucopyranoside + H2O <=> vicianose + linalool.	tmpzr1t_l9r_go_relaxed.owl					EC:3.2.1.149|MetaCyc:RXN-13701									molecular_function											owl:Class	
GO:0019647	biolink:NamedThing	formaldehyde assimilation via ribulose monophosphate cycle	The pathway in which formaldehyde is used as a carbon source in the ribulose monophosphate cycle. Methanotrophic bacteria produce formaldehyde from the oxidation of methane and methanol, and then assimilate it via the ribulose monophosphate cycle to form intermediates of the central metabolic routes that are subsequently used for biosynthesis of cell material. Three molecules of formaldehyde are assimilated, forming a three-carbon intermediate of central metabolism; in this pathway, all cellular carbon is assimilated at the oxidation level of formaldehyde.	tmpzr1t_l9r_go_relaxed.owl	ribulose monophosphate cycle|formaldehyde assimilation via RuMP cycle				MetaCyc:PWY-1861									biological_process											owl:Class	
GO:0019649	biolink:NamedThing	formaldehyde assimilation	The pathways in which formaldehyde is processed and used as a carbon source for the cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0002926	biolink:NamedThing	tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridinylation	The process whereby a wobble base uridine residue in a tRNA is modified to 5-methoxycarbonylmethyl-2-thiouridine.	tmpzr1t_l9r_go_relaxed.owl	mcm5s2U34 biosynthesis|mcm5 modification|tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridine biosynthesis							hjd	2012-01-17T02:50:54Z					biological_process											owl:Class	
GO:0046370	biolink:NamedThing	fructose biosynthetic process	The chemical reactions and pathways resulting in the formation of fructose, the ketohexose arabino-2-hexulose.	tmpzr1t_l9r_go_relaxed.owl	fructose formation|fructose anabolism|fructose synthesis|fructose biosynthesis													biological_process											owl:Class	
GO:0050158	biolink:NamedThing	orotate reductase (NADPH) activity	Catalysis of the reaction: (S)-dihydroorotate + NADP(+) = H(+) + NADPH + orotate.	tmpzr1t_l9r_go_relaxed.owl	(S)-dihydroorotate:NADP+ oxidoreductase activity|dihydro-orotic dehydrogenase activity|L-5,6-dihydro-orotate:NAD oxidoreductase activity|orotate reductase activity				RHEA:14861|KEGG_REACTION:R01866|MetaCyc:OROTATE-REDUCTASE-NADPH-RXN|EC:1.3.1.15									molecular_function											owl:Class	
GO:0004756	biolink:NamedThing	selenide, water dikinase activity	Catalysis of the reaction: ATP + H(2)O + hydrogen selenide = AMP + 3 H(+) + phosphate + selenophosphorate.	tmpzr1t_l9r_go_relaxed.owl	selenide,water dikinase activity|selenophosphate synthase activity|selenophosphate synthetase activity|ATP:selenide, water phosphotransferase activity|selenium donor protein activity				EC:2.7.9.3|KEGG_REACTION:R03595|MetaCyc:2.7.9.3-RXN|RHEA:18737|UM-BBD_reactionID:r0833|Reactome:R-HSA-8959510									molecular_function											owl:Class	
GO:0102725	biolink:NamedThing	24-methyldesmosterol reductase activity	Catalysis of the reaction: H+ + 24-methyldesmosterol + NADPH = campesterol + NADP.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-708									molecular_function											owl:Class	
GO:0050238	biolink:NamedThing	pyridoxine 5-dehydrogenase activity	Catalysis of the reaction: pyridoxine + acceptor = isopyridoxal + reduced acceptor.	tmpzr1t_l9r_go_relaxed.owl	pyridoxine 5'-dehydrogenase activity|pyridoxol 5-dehydrogenase activity|pyridoxal-5-dehydrogenase activity|pyridoxine:(acceptor) 5-oxidoreductase activity|pyridoxin 5-dehydrogenase activity|pyridoxine:acceptor 5-oxidoreductase activity				EC:1.1.99.9|MetaCyc:PYRIDOXINE-5-DEHYDROGENASE-RXN|RHEA:14497									molecular_function											owl:Class	
GO:0003017	biolink:NamedThing	lymph circulation	The flow of lymph through the body of an animal.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0034083	biolink:NamedThing	type III polyketide synthase complex	A polyketide synthase complex that consists of two identical ketosynthase polypeptides.	tmpzr1t_l9r_go_relaxed.owl	type III PKS|type III polyketide synthase|type III PKS complex													cellular_component											owl:Class	
GO:1900168	biolink:NamedThing	positive regulation of glial cell-derived neurotrophic factor production	Any process that activates or increases the frequency, rate or extent of glial cell-derived neurotrophic factor production.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of glial cell line-derived neurotrophic factor secretion|activation of glial cell line-derived neurotrophic factor secretion|positive regulation of glial cell-derived neurotrophic factor secretion|positive regulation of GDNF production							yaf	2012-03-08T03:44:47Z					biological_process											owl:Class	
GO:0018292	biolink:NamedThing	molybdenum incorporation via L-cysteinyl molybdopterin	The incorporation of molybdenum into a protein via L-cysteinyl molybdopterin.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0142									biological_process											owl:Class	
GO:0048897	biolink:NamedThing	myelination of lateral line nerve axons	The formation of compact myelin sheaths around the axons of a lateral line nerve.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0052912	biolink:NamedThing	23S rRNA (guanine(748)-N(1))-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + guanine(748) in 23S rRNA = N(1)-methylguanine(748) in 23S rRNA + S-adenosyl-L-homocysteine.	tmpzr1t_l9r_go_relaxed.owl	23S rRNA m(1)G(748) methyltransferase activity				EC:2.1.1.188|KEGG_REACTION:R07233|RHEA:42904|MetaCyc:RXN-11599									molecular_function											owl:Class	
GO:0090169	biolink:NamedThing	regulation of spindle assembly	Any process that modulates the rate, frequency or extent of spindle assembly. Spindle assembly is the aggregation, arrangement and bonding together of a set of components to form the spindle, the array of microtubules and associated molecules that serves to move duplicated chromosomes apart.	tmpzr1t_l9r_go_relaxed.owl	regulation of spindle formation							tb	2009-12-11T10:17:51Z					biological_process											owl:Class	
GO:0004401	biolink:NamedThing	histidinol-phosphatase activity	Catalysis of the reaction: L-histidinol phosphate + H(2)O = L-histidinol + phosphate.	tmpzr1t_l9r_go_relaxed.owl	histidinol phosphate phosphatase activity|HPpase activity|L-histidinol phosphate phosphatase activity|histidinolphosphatase activity|histidinolphosphate phosphatase activity|L-histidinol-phosphate phosphohydrolase activity				MetaCyc:HISTIDPHOS-RXN|EC:3.1.3.15|RHEA:14465|KEGG_REACTION:R03013									molecular_function											owl:Class	
GO:0016754	biolink:NamedThing	sinapoylglucose-malate O-sinapoyltransferase activity	Catalysis of the reaction: (S)-malate + 1-O-sinapoyl-beta-D-glucose = D-glucose + sinapoyl (S)-malate.	tmpzr1t_l9r_go_relaxed.owl	1-O-sinapoyl-beta-D-glucose:(S)-malate O-sinapoyltransferase activity|1-sinapoylglucose-L-malate sinapoyltransferase activity|sinapoylglucose:malate sinapoyltransferase activity				EC:2.3.1.92|KEGG_REACTION:R03323|RHEA:12625|MetaCyc:2.3.1.92-RXN									molecular_function											owl:Class	
GO:0093001	biolink:NamedThing	glycolysis from storage polysaccharide through glucose-1-phosphate	The chemical reactions and pathways resulting in the breakdown of a storage polysaccharide into pyruvate through a glucose-1-phosphate intermediate, with the concomitant production of a small amount of ATP and the reduction of NAD to NADH.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0002738	biolink:NamedThing	positive regulation of plasmacytoid dendritic cell cytokine production	Any process that activates or increases the frequency, rate, or extent of plasmacytoid dendritic cell cytokine production.	tmpzr1t_l9r_go_relaxed.owl	activation of plasmacytoid dendritic cell cytokine production|stimulation of plasmacytoid dendritic cell cytokine production|upregulation of plasmacytoid dendritic cell cytokine production|up-regulation of plasmacytoid dendritic cell cytokine production|up regulation of plasmacytoid dendritic cell cytokine production													biological_process											owl:Class	
GO:0002736	biolink:NamedThing	regulation of plasmacytoid dendritic cell cytokine production	Any process that modulates the frequency, rate, or extent of plasmacytoid dendritic cell cytokine production.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0038191	biolink:NamedThing	neuropilin binding	Binding to a member of the neuropilin family.	tmpzr1t_l9r_go_relaxed.owl	Nrp binding|neuropilin-binding|Nrp ligand							bf	2013-08-01T16:11:33Z					molecular_function											owl:Class	
GO:1905530	biolink:NamedThing	negative regulation of uracil import across plasma membrane	Any process that stops, prevents or reduces the frequency, rate or extent of uracil import across plasma membrane.	tmpzr1t_l9r_go_relaxed.owl								vw	2016-10-05T21:03:48Z					biological_process											owl:Class	
GO:0034871	biolink:NamedThing	1-hydroxy-4,4-dimethylpentan-3-one dehydrogenase activity	Catalysis of the reaction: 1-hydroxy-4,4-dimethylpentan-3-one = 4,4-dimethyl-3-oxopentanal + 2 H+ + 2 e-.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r1308									molecular_function											owl:Class	
GO:0031366	biolink:NamedThing	N-terminal peptidyl-asparagine deamination	The removal of an amino group from the side chain of an N-terminal asparagine residue of a protein.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0031364	biolink:NamedThing	N-terminal protein amino acid deamination, from side chain	The removal of an amino group from the side chain of an N-terminal asparagine or glutamine residue of a protein.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0035136	biolink:NamedThing	forelimb morphogenesis	The process in which the anatomical structures of the forelimb are generated and organized. The forelimbs are the front limbs of an animal, e.g. the arms of a human.	tmpzr1t_l9r_go_relaxed.owl	arm morphogenesis											GO:0035140		biological_process											owl:Class	
GO:0071140	biolink:NamedThing	resolution of mitotic recombination intermediates	The cleavage and rejoining of intermediates, mitotic recombination to produce two intact molecules in which genetic material has been exchanged.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-11-16T12:06:05Z					biological_process											owl:Class	
GO:0102631	biolink:NamedThing	caffeoylglucose 3-O-methyltransferase activity	Catalysis of the reaction: 1-O-caffeoyl-beta-D-glucose + S-adenosyl-L-methionine  <=> 1-O-feruloyl-beta-D-glucose + S-adenosyl-L-homocysteine  + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-15537									molecular_function											owl:Class	
GO:0050643	biolink:NamedThing	10-deacetylbaccatin III 10-O-acetyltransferase activity	Catalysis of the reaction: 10-deacetylbaccatin III + acetyl-CoA = baccatin III + CoA.	tmpzr1t_l9r_go_relaxed.owl	acetyl-CoA:taxan-10beta-ol O-acetyltransferase				EC:2.3.1.167|KEGG_REACTION:R06311|RHEA:20137|MetaCyc:2.3.1.167-RXN									molecular_function											owl:Class	
GO:0044836	biolink:NamedThing	D-xylose fermentation	The anaerobic enzymatic conversion of D-xylose to ethanol, yielding energy in the form of ATP.	tmpzr1t_l9r_go_relaxed.owl								jl	2014-02-19T16:14:57Z					biological_process											owl:Class	
GO:0098867	biolink:NamedThing	intramembranous bone growth	The increase in size or mass of an intramembranous bone that contributes to the shaping of the bone.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0098868	biolink:NamedThing	bone growth	The increase in size or mass of a bone that contributes to the shaping of that bone.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0032711	biolink:NamedThing	negative regulation of interleukin-27 production	Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-27 production.	tmpzr1t_l9r_go_relaxed.owl	inhibition of interleukin-27 production|negative regulation of IL-27 production|down-regulation of interleukin-27 production|down regulation of interleukin-27 production|downregulation of interleukin-27 production|negative regulation of interleukin-27 biosynthetic process											GO:0045535		biological_process											owl:Class	
GO:0008750	biolink:NamedThing	NAD(P)+ transhydrogenase (AB-specific) activity	Catalysis of the reaction: NADPH + H+ + NAD+ = NADP+ + NADH + H+. The reaction is A-specific (i.e. the pro-R hydrogen is transferred from the 4-position of reduced nicotinamide cofactor) with respect to NAD+ and B-specific (i.e. the pro-S hydrogen is transferred) with respect to NADP+.	tmpzr1t_l9r_go_relaxed.owl	NADPH:NAD+ oxidoreductase (AB-specific)|transhydrogenase activity|pyridine nucleotide transhydrogenase activity|NAD(P) transhydrogenase (AB-specific) activity				EC:1.6.1.2|MetaCyc:1.6.1.2-RXN									molecular_function											owl:Class	
GO:0015107	biolink:NamedThing	chlorate transmembrane transporter activity	Enables the transfer of chlorate, ClO3-, from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1901809	biolink:NamedThing	capsanthin biosynthetic process	The chemical reactions and pathways resulting in the formation of capsanthin.	tmpzr1t_l9r_go_relaxed.owl	capsanthin anabolism|capsanthin biosynthesis|capsanthin synthesis|capsanthin formation							yaf	2013-01-22T10:21:50Z					biological_process											owl:Class	
GO:0039554	biolink:NamedThing	suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity	Any process in which a virus stops, prevents, or reduces a host viral-induced cytoplasmic pattern recognition receptor signaling pathway by inhibiting the activity of MDA-5 (also known as IFIH1). The cytoplasmic pattern recognition receptor MDA-5 detects dsRNA synthesized during active viral replication and triggers a signaling pathway to protect the host against viral infection, for example by inducing the expression of antiviral cytokines.	tmpzr1t_l9r_go_relaxed.owl	suppression by virus of host MDA-5 signalling pathway|Inhibition of host MDA5 by virus|suppression by virus of host IFIH1 signaling pathway|suppression by virus of host MDA-5 activity|inhibition of host IFIH1/MDA5 by virus|suppression by virus of host MDA-5 signaling pathway|inhibition by virus of host MDA-5 signaling	https://github.com/geneontology/go-ontology/issues/21984						bf	2012-03-09T03:03:49Z			GO:0039539		biological_process											owl:Class	
GO:0033838	biolink:NamedThing	flavonol-3-O-glucoside glucosyltransferase activity	Catalysis of the reaction: UDP-glucose + a flavonol 3-O-beta-D-glucoside = UDP + a flavonol 3-O-beta-D-glucosyl-(1->2)-beta-D-glucoside.	tmpzr1t_l9r_go_relaxed.owl	UDP-glucose:flavonol-3-O-glucoside 2''-O-beta-D-glucosyltransferase activity				MetaCyc:2.4.1.239-RXN|EC:2.4.1.239|RHEA:18893									molecular_function											owl:Class	
GO:0140533	biolink:NamedThing	suppression of host RNAi-mediated antiviral immune response	Any process in which a symbiont stops, prevents, or reduces the rate or extent of the host's RNAi-mediated antiviral immune response. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	suppression of host RNAi-mediated gene silencing|suppression of host RNAi-mediated antiviral immunity	https://github.com/geneontology/go-ontology/issues/19958						pg	2020-10-28T07:55:27Z					biological_process											owl:Class	
GO:0085014	biolink:NamedThing	dormancy entry of symbiont in host	Entry into a dormant state of the symbiont within the host organism.	tmpzr1t_l9r_go_relaxed.owl								jl	2010-05-19T02:33:26Z					biological_process											owl:Class	
GO:0047128	biolink:NamedThing	1,2-dehydroreticulinium reductase (NADPH) activity	Catalysis of the reaction: (R)-reticuline + NADP(+) = 1,2-dehydroreticuline + H(+) + NADPH.	tmpzr1t_l9r_go_relaxed.owl	(R)-reticuline:NADP+ oxidoreductase activity|1,2-dehydroreticulinium ion reductase activity				RHEA:17569|KEGG_REACTION:R04695|MetaCyc:1.5.1.27-RXN|EC:1.5.1.27									molecular_function											owl:Class	
GO:0060383	biolink:NamedThing	positive regulation of DNA strand elongation	Any process that increases the rate, frequency or extent of DNA strand elongation. DNA strand elongation is the DNA metabolic process in which an existing DNA strand is extended by activities including the addition of nucleotides to the 3' end of the strand.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0060388	biolink:NamedThing	vitelline envelope	A glycoprotein-based structure that lies outside the plasma membrane and surrounds the egg before fertilization.	tmpzr1t_l9r_go_relaxed.owl	fertilization membrane													cellular_component											owl:Class	
GO:0002133	biolink:NamedThing	polycystin complex	A stable heterodimeric complex composed of polycystin-1 and polycystin-2.	tmpzr1t_l9r_go_relaxed.owl						Different forms of the complex differing in type of N-glycosylation of polycystin-1 can exist (endoglycosidase sensitive and endoglycosidase resistant).								cellular_component											owl:Class	
GO:1905163	biolink:NamedThing	negative regulation of phagosome maturation	Any process that stops, prevents or reduces the frequency, rate or extent of phagosome maturation.	tmpzr1t_l9r_go_relaxed.owl	down regulation of phagosome maturation|inhibition of phagosome maturation|downregulation of phagosome maturation|down-regulation of phagosome maturation							bf	2016-04-25T16:28:11Z					biological_process											owl:Class	
GO:0102439	biolink:NamedThing	3',4',5'-trimethylmyricetin 7-O-methyltransferase activity	Catalysis of the reaction: 3',4',5'-trimethylmyricetin + S-adenosyl-L-methionine  <=> 7,3',4',5'-tetramethylmyricetin + S-adenosyl-L-homocysteine  + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-13916									molecular_function											owl:Class	
GO:0008880	biolink:NamedThing	glucuronate isomerase activity	Catalysis of the reaction: D-glucuronate = D-fructuronate.	tmpzr1t_l9r_go_relaxed.owl	uronic isomerase activity|D-glucuronate aldose-ketose-isomerase activity|uronic acid isomerase activity|D-glucuronate ketol-isomerase activity|D-glucuronate isomerase activity|uronate isomerase activity				MetaCyc:GLUCUROISOM-RXN|EC:5.3.1.12|RHEA:13049									molecular_function											owl:Class	
GO:0005595	biolink:NamedThing	collagen type XII trimer	A collagen homotrimer of alpha1(XII) chains; type XII collagen triple helices may link sheet-forming or fibrillar collagens to other structures.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0070574	biolink:NamedThing	cadmium ion transmembrane transport	A process in which a cadmium ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	transmembrane cadmium transport|cadmium ion membrane transport					Note that this term is not intended for use in annotating lateral movement within membranes.		mah	2009-04-20T03:31:47Z					biological_process											owl:Class	
GO:0022629	biolink:NamedThing	chloroplast small ribosomal subunit	The small subunit of a ribosome contained within a chloroplast.	tmpzr1t_l9r_go_relaxed.owl	chloroplast ribosomal small subunit complex|chloroplast ribosomal SSU complex													cellular_component											owl:Class	
GO:0097455	biolink:NamedThing	spiny bracelet of Nageotte	Paranodal terminations of Schwann cells that do not directly contact the paranodal axon membrane. Usually found in thicker myelin.	tmpzr1t_l9r_go_relaxed.owl					NIF_Subcellular:sao937871668			pr	2012-12-19T13:02:33Z					cellular_component											owl:Class	
GO:0003247	biolink:NamedThing	post-embryonic cardiac muscle cell growth involved in heart morphogenesis	The growth of a cardiac muscle cell during the postembryonic period that contributes to the shaping of the heart.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-10-13T11:50:29Z					biological_process											owl:Class	
GO:2000636	biolink:NamedThing	positive regulation of primary miRNA processing	Any process that activates or increases the frequency, rate or extent of primary microRNA processing.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of pri-miRNA processing|positive regulation of primary microRNA processing							dph	2011-04-18T03:50:56Z					biological_process											owl:Class	
GO:0080128	biolink:NamedThing	anther septum development	The process whose specific outcome is the progression of the anther septum over time, from its formation to the mature structure. The anther septum is a thin partition or stretch of cells that are present in the anther dehiscence zone.	tmpzr1t_l9r_go_relaxed.owl								dhl	2009-04-28T04:41:16Z					biological_process											owl:Class	
GO:0090452	biolink:NamedThing	lithium ion transmembrane transport	The directed movement of lithium ions across a membrane.	tmpzr1t_l9r_go_relaxed.owl	lithium ion uptake|lithium ion import							tb	2012-09-24T14:04:41Z					biological_process											owl:Class	
GO:0044874	biolink:NamedThing	lipoprotein localization to outer membrane	A process in which a lipoprotein is transported to, or maintained in, a specific location in an outer membrane.	tmpzr1t_l9r_go_relaxed.owl								jl	2014-11-25T16:30:30Z					biological_process											owl:Class	
GO:0005476	biolink:NamedThing	carnitine:acyl carnitine antiporter activity	Catalysis of the reaction: carnitine (mitochondrial) + acyl carnitine (cytoplasm) = carnitine (cytoplasm) + acyl carnitine (mitochondrial).	tmpzr1t_l9r_go_relaxed.owl	fatty acyl carnitine carrier|carnitine/acyl carnitine carrier activity|carnitine:acyl carnitine carrier activity													molecular_function											owl:Class	
GO:0032523	biolink:NamedThing	silicon efflux transmembrane transporter activity	Enables the transfer of silicon from the inside of the cell to the outside of the cell across a membrane.	tmpzr1t_l9r_go_relaxed.owl	silicon efflux transporter activity													molecular_function											owl:Class	
GO:0140615	biolink:NamedThing	ATP-dependent citrate lyase complex	A protein complex that catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA.	tmpzr1t_l9r_go_relaxed.owl	citrate synthase complex|citrate lyase complex	https://github.com/geneontology/go-ontology/issues/21028						pg	2021-03-08T14:15:18Z					cellular_component											owl:Class	
GO:2000596	biolink:NamedThing	negative regulation of optic nerve formation	Any process that stops, prevents or reduces the frequency, rate or extent of optic nerve formation.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of CN II formation|negative regulation of CN II biosynthesis							yaf	2011-04-11T03:41:35Z					biological_process											owl:Class	
GO:0044673	biolink:NamedThing	7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase complex	A heterodimer which catalyses the reaction of 5-amino-6-(D-ribitylamino)uracil and 4-hydroxyphenylpyruvate to form 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO), an intermediate of coenzyme F420.	tmpzr1t_l9r_go_relaxed.owl	FO-synthase complex							jl	2012-08-09T10:49:05Z					cellular_component											owl:Class	
GO:0032492	biolink:NamedThing	detection of molecule of oomycetes origin	The series of events in which a stimulus from a molecule of oomycetes origin is received and converted into a molecular signal.	tmpzr1t_l9r_go_relaxed.owl	detection of oomycetes associated molecule													biological_process											owl:Class	
GO:0006301	biolink:NamedThing	postreplication repair	The conversion of DNA-damage induced single-stranded gaps into large molecular weight DNA after replication. Includes pathways that remove replication-blocking lesions in conjunction with DNA replication.	tmpzr1t_l9r_go_relaxed.owl	postreplication DNA repair				Wikipedia:Postreplication_repair									biological_process											owl:Class	
GO:0000951	biolink:NamedThing	methionine catabolic process to 3-methylthiopropanol	The chemical reactions and pathways involving the catabolism of branched chain amino acids to produce branched chain alcohols with one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. When methionine is used as the substrate, 3-methylthiopropanol is produced. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of alcohols, often collectively referred to as fusel alcohols. Depending on the redox state of the cells, carboxylic acid derivatives may be produced instead of alcohols.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1990269	biolink:NamedThing	RNA polymerase II C-terminal domain phosphoserine binding	Binding to phosphorylated serine residues in the C-terminal domain of RNA polymerase II.	tmpzr1t_l9r_go_relaxed.owl	RNAP II C-terminal domain phosphoserine binding|RNA Pol II C-terminal domain phosphoserine binding							tb	2014-01-11T00:34:59Z					molecular_function											owl:Class	
GO:0099122	biolink:NamedThing	RNA polymerase II C-terminal domain binding	Binding to the C-terminal domain (CTD) of the largest subunit of RNA polymerase II. The CTD is comprised of repeats of a heptapeptide with the consensus sequence YSPTSPS. The number of repeats varies with the species and a minimum number of repeats is required for RNAP II function.	tmpzr1t_l9r_go_relaxed.owl	RNAP II C-terminal binding													molecular_function											owl:Class	
GO:0018116	biolink:NamedThing	peptidyl-lysine adenylylation	The adenylylation of peptidyl-lysine to form peptidyl-N6-(phospho-5'-adenosine)-L-lysine.	tmpzr1t_l9r_go_relaxed.owl	peptidyl-lysine adenylation				RESID:AA0227									biological_process											owl:Class	
GO:0030774	biolink:NamedThing	anthranilate N-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + anthranilate = N-methylanthranilate + S-adenosyl-L-homocysteine + H(+).	tmpzr1t_l9r_go_relaxed.owl	anthranilic acid N-methyltransferase activity|S-adenosyl-L-methionine:anthranilate N-methyltransferase activity				KEGG_REACTION:R00984|MetaCyc:ANTHRANILATE-N-METHYLTRANSFERASE-RXN|RHEA:12180|EC:2.1.1.111									molecular_function											owl:Class	
GO:0120063	biolink:NamedThing	stomach smooth muscle contraction	A process in which force is generated within gastric smooth muscle tissue, resulting in a change in muscle geometry. This process occurs throughout the length of the stomach.	tmpzr1t_l9r_go_relaxed.owl								krc	2017-06-13T22:20:16Z					biological_process											owl:Class	
GO:0004798	biolink:NamedThing	thymidylate kinase activity	Catalysis of the reaction: ATP + thymidine 5'-phosphate = ADP + thymidine 5'-diphosphate.	tmpzr1t_l9r_go_relaxed.owl	thymidine 5'-monophosphate kinase activity|dTMP kinase activity|thymidylic kinase activity|thymidylate monophosphate kinase activity|ATP:dTMP phosphotransferase activity|deoxythymidine 5'-monophosphate kinase activity|thymidylic acid kinase activity|thymidine monophosphate kinase activity|TMPK activity				EC:2.7.4.9|MetaCyc:DTMPKI-RXN|RHEA:13517									molecular_function											owl:Class	
GO:0033517	biolink:NamedThing	myo-inositol hexakisphosphate metabolic process	The chemical reactions and pathways involving phytic acid, myo-inositol hexakisphosphate, a regulator of intracellular signaling, a highly abundant animal anti-nutrient and a phosphate and mineral storage compound in plant seeds.	tmpzr1t_l9r_go_relaxed.owl	phytate metabolic process|myo-inositol hexakisphosphate metabolism|phytate metabolism													biological_process											owl:Class	
GO:0043184	biolink:NamedThing	vascular endothelial growth factor receptor 2 binding	Binding to a vascular endothelial growth factor receptor 2.	tmpzr1t_l9r_go_relaxed.owl	kinase domain region binding|VEGFR 2 binding|KDR binding|Flk-1 binding|VEGF receptor 2 binding													molecular_function											owl:Class	
GO:0016009	biolink:NamedThing	minor mitochondrial derivative	The smaller of the two mitochondrial derivatives that arise by the unfolding of the Nebenkern during flagellum elongation.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/20737												cellular_component											owl:Class	
GO:0120147	biolink:NamedThing	Formylglycine-generating oxidase activity	Catalysis of the reaction: A [sulfatase]-L-cysteine + O(2) + 2 a thiol = a [sulfatase]-3-oxo-L-alanine + hydrogen sulfide + a disulfide + H(2)O.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-16226|RHEA:51152|EC:1.8.3.7			krc	2018-04-06T15:38:52Z					molecular_function											owl:Class	
GO:0034854	biolink:NamedThing	4,4-dimethyl-3-oxopentanoate decarboxylase activity	Catalysis of the reaction: 4,4-dimethyl-3-oxopentanoate + H+ = 3,3-dimethyl-2-butanone + CO2.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r1280									molecular_function											owl:Class	
GO:0019866	biolink:NamedThing	organelle inner membrane	The inner, i.e. lumen-facing, lipid bilayer of an organelle envelope; usually highly selective to most ions and metabolites.	tmpzr1t_l9r_go_relaxed.owl						See also the cellular component term 'outer membrane ; GO:0019867'.								cellular_component											owl:Class	
GO:0000346	biolink:NamedThing	transcription export complex	The transcription export (TREX) complex couples transcription elongation by RNA polymerase II to mRNA export. The complex associates with the polymerase and travels with it along the length of the transcribed gene. TREX is composed of the THO transcription elongation complex as well as other proteins that couple THO to mRNA export proteins. The TREX complex is known to be found in a wide range of eukaryotes, including S. cerevisiae and metazoans.	tmpzr1t_l9r_go_relaxed.owl	TREX complex													cellular_component											owl:Class	
GO:0048161	biolink:NamedThing	double layer follicle stage	The stage in oogenesis when a double layer of distinct follicle cells surrounds the oocyte. An example of this process is found in Mus musculus.	tmpzr1t_l9r_go_relaxed.owl	mammalian oogenesis stage 4													biological_process											owl:Class	
GO:0102561	biolink:NamedThing	D-ribose 2,5-bisphosphate 2-phosphohydrolase activity	Catalysis of the reaction: H2O + D-ribofuranose 2,5-bisphosphate <=> hydrogenphosphate + D-ribofuranose 5-phosphate.	tmpzr1t_l9r_go_relaxed.owl					RHEA:41616|EC:3.1.4.57|MetaCyc:RXN-14996									molecular_function											owl:Class	
GO:0015913	biolink:NamedThing	short-chain fatty acid import	The directed movement of short-chain fatty acids into a cell or organelle. Short-chain fatty acids are fatty acids with a chain length of less than C6.	tmpzr1t_l9r_go_relaxed.owl	short-chain fatty acid uptake													biological_process											owl:Class	
GO:0102127	biolink:NamedThing	8-oxoguanine deaminase activity	Catalysis of the reaction: H+ + 7,8-dihydro-8-oxoguanine + H2O <=> 7,9-dihydro-1H-purine-2,6,8(3H)-trione + ammonium.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-11455|EC:3.5.4.32|RHEA:32067									molecular_function											owl:Class	
GO:0018446	biolink:NamedThing	pinocarveol dehydrogenase activity	Catalysis of the reaction: pinocarveol = pinocarvone + 2 H+ + 2 e-.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0717									molecular_function											owl:Class	
GO:0031265	biolink:NamedThing	CD95 death-inducing signaling complex	A protein complex formed upon binding of Fas/CD95/APO-1 to its ligand. The complex includes FADD/Mort1, procaspase-8/10 and c-FLIP in addition to the ligand-bound receptor.	tmpzr1t_l9r_go_relaxed.owl	Fas death-inducing signaling complex|CD95 DISC|CD95 death-inducing signalling complex													cellular_component											owl:Class	
GO:0022028	biolink:NamedThing	tangential migration from the subventricular zone to the olfactory bulb	The migration of cells in the telencephalon from the subventricular zone to the olfactory bulb in which cells move orthogonally to the direction of radial migration and do not use radial glial cell processes as substrates for migration.	tmpzr1t_l9r_go_relaxed.owl	rostral migratory stream migration													biological_process											owl:Class	
GO:0055096	biolink:NamedThing	low-density lipoprotein particle mediated signaling	A series of molecular signals mediated by the detection of low-density lipoprotein particle.	tmpzr1t_l9r_go_relaxed.owl	low-density lipoprotein particle mediated signal transduction|low-density lipoprotein mediated signalling|low-density lipoprotein particle-mediated signaling													biological_process											owl:Class	
GO:0055095	biolink:NamedThing	lipoprotein particle mediated signaling	A series of molecular signals mediated by the detection of a lipoprotein particle.	tmpzr1t_l9r_go_relaxed.owl	lipoprotein particle-mediated signaling|lipoprotein mediated signalling|lipoprotein particle mediated signal transduction													biological_process											owl:Class	
GO:0034803	biolink:NamedThing	3-hydroxy-2-naphthoate 2,3-dioxygenase activity	Catalysis of the reaction: 3-hydroxy-2-naphthoate + O2 = (3E)-3-[(6Z)-6-(carboxymethylene)cyclohexa-2,4-dien-1-ylidene]-2-oxopropanate.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r1104|EC:1.13.11.-									molecular_function											owl:Class	
GO:0005157	biolink:NamedThing	macrophage colony-stimulating factor receptor binding	Binding to a macrophage colony-stimulating factor receptor.	tmpzr1t_l9r_go_relaxed.owl	M-CSF receptor binding|macrophage colony stimulating factor receptor binding|macrophage colony-stimulating factor receptor ligand													molecular_function											owl:Class	
GO:0046729	biolink:NamedThing	viral procapsid	A stable empty viral capsid produced during the assembly of viruses.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:1990055	biolink:NamedThing	phenylacetaldehyde synthase activity	Catalyzes the reaction: L-phenylalanine + O2 + H2O -> phenylacetaldehyde + ammonia + hydrogen peroxide + CO2.	tmpzr1t_l9r_go_relaxed.owl	aromatic aldehyde synthase				RHEA:55532|EC:4.1.1.109			tb	2013-02-25T20:22:35Z					molecular_function											owl:Class	
GO:1990960	biolink:NamedThing	basophil homeostasis	The process of regulating the proliferation and elimination of basophils such that the total number of basophils within a whole or part of an organism is stable over time in the absence of an outside stimulus.	tmpzr1t_l9r_go_relaxed.owl	basophilic leucocyte homeostasis							sl	2016-06-06T22:38:22Z					biological_process											owl:Class	
GO:0001681	biolink:NamedThing	sialate O-acetylesterase activity	Catalysis of the reaction: N-acetyl-O-acetylneuraminate (free or glycosidically bound) + H2O = N-acetylneuraminate + acetate.	tmpzr1t_l9r_go_relaxed.owl	N-acetylneuraminate acetyltransferase activity|sialate 9(4)-O-acetylesterase activity|N-acyl-O-acetylneuraminate O-acetylhydrolase activity				MetaCyc:SIALATE-O-ACETYLESTERASE-RXN|EC:3.1.1.53									molecular_function											owl:Class	
GO:0008126	biolink:NamedThing	acetylesterase activity	Catalysis of the reaction: an acetic ester + H2O = an alcohol + acetate.	tmpzr1t_l9r_go_relaxed.owl	acetic ester hydrolase activity|citrus acetylesterase|p-nitrophenyl acetate esterase|C-esterase (in animal tissues)|acetic-ester acetylhydrolase activity|chloroesterase				EC:3.1.1.6|RHEA:12957|UM-BBD_reactionID:r0170|MetaCyc:ACETYLESTERASE-RXN									molecular_function											owl:Class	
GO:0017098	biolink:NamedThing	sulfonylurea receptor binding	Binding to a sulfonylurea receptor, a regulatory subunit of the ATP-sensitive potassium ion channel.	tmpzr1t_l9r_go_relaxed.owl	sulphonylurea receptor binding|sulfonylurea receptor ligand													molecular_function											owl:Class	
GO:0006009	biolink:NamedThing	glucose 1-phosphate phosphorylation	The process of introducing a phosphate group into glucose 1-phosphate to produce glucose bisphosphate.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1990869	biolink:NamedThing	cellular response to chemokine	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemokine stimulus.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-09-25T16:39:55Z					biological_process											owl:Class	
GO:0061726	biolink:NamedThing	mitochondrion disassembly	The disaggregation of a mitochondrion into its constituent components.	tmpzr1t_l9r_go_relaxed.owl	mitochondrion degradation							dph	2015-07-08T13:59:16Z					biological_process											owl:Class	
GO:0010625	biolink:NamedThing	positive regulation of Schwann cell proliferation	Any process that increases the frequency or rate of the multiplication or reproduction of Schwann cells, resulting in the expansion of their population. Schwann cells are a type of glial cell in the peripheral nervous system.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0106004	biolink:NamedThing	tRNA (guanine-N7)-methylation	The process whereby a guanine in a tRNA is methylated at the N7 position of guanine.	tmpzr1t_l9r_go_relaxed.owl								hjd	2017-04-07T18:17:38Z					biological_process											owl:Class	
GO:0047354	biolink:NamedThing	sphingosine cholinephosphotransferase activity	Catalysis of the reaction: CDP-choline + sphingosine = CMP + H(+) + sphingosyl-phosphocholine.	tmpzr1t_l9r_go_relaxed.owl	cytidine diphosphocholine-sphingosine cholinephosphotransferase activity|sphingosine choline phosphotransferase activity|CDP-choline:sphingosine cholinephosphotransferase activity|CDP-choline-sphingosine cholinephosphotransferase activity|phosphorylcholine-sphingosine transferase activity				EC:2.7.8.10|MetaCyc:2.7.8.10-RXN|KEGG_REACTION:R01929|RHEA:21224									molecular_function											owl:Class	
GO:0099037	biolink:NamedThing	anchored component of presynaptic endosome membrane	The component of the presynaptic endosome membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0047356	biolink:NamedThing	CDP-ribitol ribitolphosphotransferase activity	Catalysis of the reaction: ribitol phosphate(n) + CDP-ribitol = ribitol phosphate(n+1) + CMP.	tmpzr1t_l9r_go_relaxed.owl	teichoate synthetase activity|teichoic-acid synthase activity|CDPribitol ribitolphosphotransferase activity|poly(ribitol phosphate) synthetase activity|polyribitol phosphate synthetase activity|CDP-ribitol:poly(ribitol phosphate) ribitolphosphotransferase activity|polyribitol phosphate polymerase activity|teichoate synthase activity				RHEA:13353|EC:2.7.8.14|MetaCyc:2.7.8.14-RXN									molecular_function											owl:Class	
GO:1903527	biolink:NamedThing	positive regulation of membrane tubulation	Any process that activates or increases the frequency, rate or extent of membrane tubulation.	tmpzr1t_l9r_go_relaxed.owl	up regulation of plasma membrane tubulation|up regulation of membrane tubulation|positive regulation of plasma membrane tubulation|activation of membrane tubulation|up-regulation of plasma membrane tubulation|up-regulation of membrane tubulation|upregulation of plasma membrane tubulation|upregulation of membrane tubulation|activation of plasma membrane tubulation							pm	2014-10-07T12:52:53Z					biological_process											owl:Class	
GO:0102607	biolink:NamedThing	3beta-hydroxy-12,15-cassadiene-11-one 2-hydroxylase activity	Catalysis of the reaction: 3beta-hydroxy-12,15-cassadiene-11-one + NADPH + O2 + H+ <=> 2beta,3beta-dihydroxy-12,15-cassadiene-11-one + NADP + H2O.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-15433									molecular_function											owl:Class	
GO:0039649	biolink:NamedThing	modulation by virus of host ubiquitin-protein ligase activity	The process in which a virus effects a change in host ubiquitin-protein ligase activity. Ubiquitin-protein ligase activity catalyzes the reaction: ATP + ubiquitin + protein lysine = AMP + diphosphate + protein N-ubiquityllysine.	tmpzr1t_l9r_go_relaxed.owl	modulation of host E3 ubiquitin ligases by virus							bf	2012-10-09T15:26:56Z					biological_process											owl:Class	
GO:0008058	biolink:NamedThing	ocellus pigment granule organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of intracellular pigment storage granules in the ocellus.	tmpzr1t_l9r_go_relaxed.owl	ocellus pigment granule organization and biogenesis|ocellus pigment granule organisation													biological_process											owl:Class	
GO:0051721	biolink:NamedThing	protein phosphatase 2A binding	Binding to protein phosphatase 2A.	tmpzr1t_l9r_go_relaxed.owl	protein phosphatase 2 binding													molecular_function											owl:Class	
GO:0045549	biolink:NamedThing	9-cis-epoxycarotenoid dioxygenase activity	Catalysis of the reactions: a 9-cis-epoxycarotenoid + O2 = 2-cis,4-trans-xanthoxin + a 12'-apo-carotenal; 9-cis-violaxanthin + O2 = 2-cis,4-trans-xanthoxin + (3S,5R,6S)-5,6-epoxy-3-hydroxy-5,6-dihydro-12'-apo-beta-caroten-12'-al; and 9'-cis-neoxanthin + O2 = 2-cis,4-trans-xanthoxin + (3S,5R,6R)-5,6-dihydroxy-6,7-didehydro-5,6-dihydro-12'-apo-beta-caroten-12'-al.	tmpzr1t_l9r_go_relaxed.owl	neoxanthin cleavage enzyme|AtNCED3|9-cis-epoxycarotenoid 11,12-dioxygenase activity|NCED|nine-cis-epoxycarotenoid dioxygenase activity|PvNCED1|VP14				EC:1.13.11.51									molecular_function											owl:Class	
GO:0140355	biolink:NamedThing	cargo receptor ligand activity	The activity of a gene product that interacts with a cargo receptor and initiates endocytosis.	tmpzr1t_l9r_go_relaxed.owl	cargo							pg	2019-05-27T09:56:50Z					molecular_function											owl:Class	
GO:0060421	biolink:NamedThing	positive regulation of heart growth	Any process that increases the rate or extent of heart growth. Heart growth is the increase in size or mass of the heart.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0034567	biolink:NamedThing	chromate reductase activity	Catalysis of the reaction: chromate = chromium (III).	tmpzr1t_l9r_go_relaxed.owl					EC:1.97.1.-|UM-BBD_reactionID:r0884									molecular_function											owl:Class	
GO:0035210	biolink:NamedThing	prepupal development	The process whose specific outcome is the progression of the prepupa over time, from its formation to the mature structure. The prepupal stage is a life stage interposed between the larval and the pupal stages in insects that undergo a complete metamorphosis. The start of the pre-pupal stage is marked by pupariation, and the end is marked by pupation.	tmpzr1t_l9r_go_relaxed.owl						See also the fly_anatomy.ontology term 'prepupa ; FBbt:00002952'.								biological_process											owl:Class	
GO:0015383	biolink:NamedThing	sulfate:bicarbonate antiporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sulfate(out) + bicarbonate(in) = sulfate(in) + bicarbonate(out).	tmpzr1t_l9r_go_relaxed.owl	sulphate:bicarbonate antiporter activity													molecular_function											owl:Class	
GO:0004998	biolink:NamedThing	transferrin receptor activity	Combining selectively with transferrin, and delivering transferrin into the cell via endocytosis. Transferrin is a major iron carrier protein in vertebrates.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0002511	biolink:NamedThing	central B cell receptor editing	Receptor editing occurring in B cells in the bone marrow.	tmpzr1t_l9r_go_relaxed.owl	central B-cell receptor editing|central B lymphocyte receptor editing|central B-lymphocyte receptor editing													biological_process											owl:Class	
GO:0046990	biolink:NamedThing	N-hydroxyarylamine O-acetyltransferase activity	Catalysis of the reaction: acetyl-CoA + an N-hydroxyarylamine = CoA + an N-acetoxyarylamine.	tmpzr1t_l9r_go_relaxed.owl	acetyl-CoA:N-hydroxyarylamine O-acetyltransferase activity|arylhydroxamate N,O-acetyltransferase activity|N-hydroxy-2-aminofluorene-O-acetyltransferase activity				EC:2.3.1.118|RHEA:20277|MetaCyc:2.3.1.118-RXN									molecular_function											owl:Class	
GO:0003896	biolink:NamedThing	DNA primase activity	Catalysis of the synthesis of a short RNA primer on a DNA template, providing a free 3'-OH that can be extended by DNA-directed DNA polymerases.	tmpzr1t_l9r_go_relaxed.owl					EC:2.7.7.101							GO:0003898|GO:0003897		molecular_function											owl:Class	
GO:0047056	biolink:NamedThing	(S)-canadine synthase activity	Catalysis of the reaction: (S)-tetrahydrocolumbamine + [reduced NADPH--hemoprotein reductase] + O2 -> (S)-canadine + [oxidized NADPH--hemoprotein reductase] + 2 H2O.	tmpzr1t_l9r_go_relaxed.owl	(S)-tetrahydroberberine synthase activity|(S)-tetrahydrocolumbamine oxidase (methylenedioxy-bridge-forming) activity	https://github.com/geneontology/go-ontology/issues/21133			RHEA:21456|MetaCyc:1.1.3.36-RXN|KEGG_REACTION:R04400|EC:1.14.19.68									molecular_function											owl:Class	
GO:0009550	biolink:NamedThing	primary plasmodesma	A plasmodesma that consists of a simple, single channel; found predominantly in young tissue and formed as a function of cell plate formation during cytokinesis.	tmpzr1t_l9r_go_relaxed.owl	simple plasmodesma													cellular_component											owl:Class	
GO:0070285	biolink:NamedThing	pigment cell development	The process whose specific outcome is the progression of a pigment cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a pigment cell fate.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0017122	biolink:NamedThing	protein N-acetylglucosaminyltransferase complex	A protein complex capable of protein N-acetylglucosaminyltransferase activity, the addition of nucleotide-activated sugars onto the polypeptide according to reaction: UDP-N-acetyl-D-glucosamine + protein = UDP + 4-N-(N-acetyl-D-glucosaminyl)-protein. The complex has different compositions in different species: In mammals it is often a homotrimer, in bacteria a heterotetramer of 2 different subunits.	tmpzr1t_l9r_go_relaxed.owl	UDP-N-acetylglucosamine-peptide N-acetylglucosaminyltransferase|O-GlcNAc transferase complex	https://github.com/geneontology/go-ontology/issues/16994												cellular_component											owl:Class	
GO:0034455	biolink:NamedThing	t-UTP complex	A protein complex that forms a subcomplex of the 90S preribosome and is required for the subsequent assembly of the rest of the preribosome. In S. cerevisiae, it is composed of Utp5p, Utp4p, Nan1p, Utp8p, Utp9p, Utp10 and Utp15p.	tmpzr1t_l9r_go_relaxed.owl	Nan1p-containing subcomplex of 90S preribosome					Note that the term name uses Saccharomyces gene product names because no other names have yet arisen for this complex; the term nevertheless can be used for analogous complexes in other eukaryotes, and the name can be changed if better wording is found.								cellular_component											owl:Class	
GO:0034265	biolink:NamedThing	isopentenyl adenine biosynthetic process	The chemical reactions and pathways resulting in the formation of the cytokinin 6-isopentenyladenine.	tmpzr1t_l9r_go_relaxed.owl	isopentenyl adenine formation|isopentenyl adenine anabolism|isopentenyladenine biosynthetic process|isopentenyl adenine synthesis|isopentenyl adenine biosynthesis													biological_process											owl:Class	
GO:0099142	biolink:NamedThing	intracellularly ATP-gated ion channel activity	Enables the transmembrane transfer of an ion by a channel that opens when ATP has been bound by the channel complex or one of its constituent parts on the intracellular side of the plasma membrane.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0008867	biolink:NamedThing	galactarate dehydratase activity	Catalysis of the reaction: galactarate = 5-dehydro-4-deoxy-D-glucarate + H(2)O.	tmpzr1t_l9r_go_relaxed.owl	D-galactarate hydro-lyase (5-dehydro-4-deoxy-D-glucarate-forming)|D-galactarate hydro-lyase activity				MetaCyc:GALACTARDEHYDRA-RXN|KEGG_REACTION:R05608|RHEA:16005|EC:4.2.1.42									molecular_function											owl:Class	
GO:1905375	biolink:NamedThing	cellular response to homocysteine	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a homocysteine stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to Hcy|cellular response to 2-amino-4-mercaptobutyric acid|cellular response to 2-amino-4-sulfanylbutanoic acid							sl	2016-08-17T20:18:00Z					biological_process											owl:Class	
GO:0106272	biolink:NamedThing	protein localization to ERGIC	A process in which a protein is transported to, or maintained in, a location within the endoplasmic reticulum-Golgi intermediate compartment (ERGIC).	tmpzr1t_l9r_go_relaxed.owl								hjd	2020-07-01T17:04:35Z					biological_process											owl:Class	
GO:0050023	biolink:NamedThing	L-fuconate dehydratase activity	Catalysis of the reaction: L-fuconate = 2-dehydro-3-deoxy-L-fuconate + H(2)O.	tmpzr1t_l9r_go_relaxed.owl	L-fuconate hydratase activity|L-fuconate hydro-lyase (2-dehydro-3-deoxy-L-fuconate-forming)|L-fuconate hydro-lyase activity				MetaCyc:L-FUCONATE-HYDRATASE-RXN|RHEA:22772|EC:4.2.1.68|KEGG_REACTION:R03688									molecular_function											owl:Class	
GO:0001118	biolink:NamedThing	transcription ternary complex disassembly	The disaggregation of a transcription ternary complex, composed of RNA polymerase, template DNA, and an RNA transcript, into its constituent components.	tmpzr1t_l9r_go_relaxed.owl	transcription protein-DNA-RNA complex disassembly							krc	2010-12-03T04:11:34Z					biological_process											owl:Class	
GO:0003416	biolink:NamedThing	endochondral bone growth	The increase in size or mass of an endochondral bone that contributes to the shaping of the bone.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-12-22T08:52:55Z					biological_process											owl:Class	
GO:0043882	biolink:NamedThing	malate:sodium symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: malate(out) + Na+(out) = malate(in) + Na+(in).	tmpzr1t_l9r_go_relaxed.owl	malate:sodium cotransporter activity|sodium-dependent malate transporter|malate:Na+ symporter activity|malate/sodium symporter activity|malate-sodium symporter activity|malate/sodium cotransporter activity|sodium/malate symporter activity|malate Na(+) symporter activity|sodium:malate symporter activity|Na(+)-malate symporter activity|Na+:malate symporter activity													molecular_function											owl:Class	
GO:0047413	biolink:NamedThing	N(alpha)-benzyloxycarbonylleucine hydrolase activity	Catalysis of the reaction: N-benzyloxycarbonyl-L-leucine + H(2)O + H(+) = L-leucine + benzyl alcohol + CO(2).	tmpzr1t_l9r_go_relaxed.owl	nalpha-benzyloxycarbonylleucine hydrolase activity|nalpha-benzyloxycarbonyl amino acid urethane hydrolase IV|nalpha-benzyloxycarbonyl-L-leucine urethanehydrolase activity|benzyloxycarbonylleucine hydrolase activity|alpha-N-benzyloxycarbonyl-L-leucine urethanehydrolase activity				MetaCyc:3.5.1.64-RXN|EC:3.5.1.64|KEGG_REACTION:R02552|RHEA:18901									molecular_function											owl:Class	
GO:0008486	biolink:NamedThing	diphosphoinositol-polyphosphate diphosphatase activity	Catalysis of the reaction: diphospho-myo-inositol polyphosphate + H2O = myo-inositol polyphosphate + phosphate.	tmpzr1t_l9r_go_relaxed.owl	diphosphoinositol-polyphosphate phosphohydrolase activity|DIPP activity|diphosphoinositol polyphosphate phosphohydrolase activity|diphospho-myo-inositol-polyphosphate diphosphohydrolase activity				EC:3.6.1.52|KEGG_REACTION:R05777|MetaCyc:3.6.1.52-RXN									molecular_function											owl:Class	
GO:0000334	biolink:NamedThing	3-hydroxyanthranilate 3,4-dioxygenase activity	Catalysis of the reaction: 3-hydroxyanthranilate + O(2) = cis,cis-2-amino-3-(3-oxoprop-1-enyl)but-2-enedioate + H(+).	tmpzr1t_l9r_go_relaxed.owl	3-hydroxyanthranilic acid dioxygenase activity|3-hydroxyanthranilate:oxygen 3,4-oxidoreductase (decyclizing)|3HAO|3-hydroxyanthranilic acid oxygenase activity|3-hydroxyanthranilate oxygenase activity|3-hydroxyanthranilic oxygenase activity				RHEA:17953|MetaCyc:1.13.11.6-RXN|Reactome:R-HSA-71218|KEGG_REACTION:R02665|UM-BBD_reactionID:r1027|EC:1.13.11.6									molecular_function											owl:Class	
GO:0102365	biolink:NamedThing	taxusin 2-alpha-hydroxylase activity	Catalysis of the reaction: taxusin + NADPH + O2 + H+ = 2-alpha-hydroxytaxusin + NADP + H2O.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-13486									molecular_function											owl:Class	
GO:0034363	biolink:NamedThing	intermediate-density lipoprotein particle	A triglyceride-rich lipoprotein particle that typically contains APOB100, APOE and APOCs and has a density of 1.006-1.019 g/ml and a diameter of between 25-30 nm. IDL particles are found in blood and are formed by the delipidation of very-low-density lipoprotein particles (VLDL). IDL particles are removed from blood by the liver, following binding to the APOE receptor, or are converted to low-density lipoprotein (LDL).	tmpzr1t_l9r_go_relaxed.owl	IDL complex|IDL particle|intermediate-density lipoprotein complex													cellular_component											owl:Class	
GO:0036246	biolink:NamedThing	phytochelatin 2 import into vacuole	The directed movement of phytochelatin 2 (PC2) into the vacuole. Phytochelatin 2 is a glutathione-related peptide composed of (gamma-Glu-Cys)n-Gly where n=2, and where the Glu and Cys residues are linked through a gamma-carboxylamide bond.	tmpzr1t_l9r_go_relaxed.owl	PC2 import into vacuole							bf	2012-05-31T11:09:20Z					biological_process											owl:Class	
GO:0046547	biolink:NamedThing	trans-aconitate 3-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine(1+) + trans-aconitate = (E)-2-(methoxycarbonylmethyl)but-2-enedioate + S-adenosyl-L-homocysteine.	tmpzr1t_l9r_go_relaxed.owl	S-adenosyl-L-methionine:(E)-prop-1-ene-1,2,3-tricarboxylate 3'-O-methyltransferase activity				EC:2.1.1.145|KEGG_REACTION:R05764|RHEA:22200|MetaCyc:2.1.1.145-RXN									molecular_function											owl:Class	
GO:0000210	biolink:NamedThing	NAD+ diphosphatase activity	Catalysis of the reaction: NAD+ + H2O = AMP + NMN.	tmpzr1t_l9r_go_relaxed.owl	NAD pyrophosphatase activity|nicotinamide adenine dinucleotide pyrophosphatase activity|NAD(+) pyrophosphatase activity|NAD+ pyrophosphatase activity|NAD diphosphatase activity|NADP pyrophosphatase activity|NAD+ phosphohydrolase activity|NADH pyrophosphatase activity				EC:3.6.1.22|RHEA:11800|MetaCyc:NADPYROPHOSPHAT-RXN									molecular_function											owl:Class	
GO:0003856	biolink:NamedThing	3-dehydroquinate synthase activity	Catalysis of the reaction: 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate = 3-dehydroquinate + phosphate.	tmpzr1t_l9r_go_relaxed.owl					EC:4.2.3.4|KEGG_REACTION:R03083|RHEA:21968|MetaCyc:3-DEHYDROQUINATE-SYNTHASE-RXN									molecular_function											owl:Class	
GO:0080191	biolink:NamedThing	secondary thickening	Lateral growth of a plant axis (shoot axis or root) that is an increase in thickness resulting from formation of tissue from a secondary thickening meristem.	tmpzr1t_l9r_go_relaxed.owl						Occurs in shoot axes in some monocotyledons such as Dracaena, and rarely in roots of monocotyledons. Distinct from primary thickening, because it is distant from and generally discontinuous with the apical meristem.		dhl	2012-12-06T15:50:33Z					biological_process											owl:Class	
GO:0008302	biolink:NamedThing	female germline ring canal formation, actin assembly	Recruitment and organization of actin filaments in female germline ring canals.	tmpzr1t_l9r_go_relaxed.owl	nurse cell ring canal formation, actin assembly|ring canal formation, actin assembly|ovarian ring canal formation, actin assembly													biological_process											owl:Class	
GO:0033534	biolink:NamedThing	verbascose biosynthetic process	The chemical reactions and pathways resulting in the formation of verbascose, the pentasaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside.	tmpzr1t_l9r_go_relaxed.owl	verbascose anabolism|verbascose synthesis|verbascose biosynthesis|verbascose formation													biological_process											owl:Class	
GO:0050846	biolink:NamedThing	teichuronic acid metabolic process	The chemical reactions and pathways involving teichuronic acid, a polymer containing chains of uronic acids and N-acetylglucosamine found in the cell wall, membrane or capsule of Gram-positive bacteria.	tmpzr1t_l9r_go_relaxed.owl	teichuronic acid metabolism													biological_process											owl:Class	
GO:0018453	biolink:NamedThing	2-hydroxytetrahydrofuran dehydrogenase activity	Catalysis of the reaction: 2-hydroxytetrahydrofuran = 2 H+ + 2 e- + butyrolactone.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0018									molecular_function											owl:Class	
GO:0036189	biolink:NamedThing	abieta-7,13-diene hydroxylase activity	Catalysis of the reaction: abieta-7,13-diene + NADPH + H+ + O2 = abieta-7,13-dien-18-ol + NADP+ + H2O.	tmpzr1t_l9r_go_relaxed.owl	abietadiene hydroxylase				RHEA:26217|EC:1.14.14.144|MetaCyc:RXN-8507|KEGG_REACTION:R06351			bf	2012-04-19T10:57:05Z					molecular_function											owl:Class	
GO:1903664	biolink:NamedThing	regulation of asexual reproduction	Any process that modulates the frequency, rate or extent of asexual reproduction.	tmpzr1t_l9r_go_relaxed.owl								pf	2014-11-26T21:13:24Z					biological_process											owl:Class	
GO:0019548	biolink:NamedThing	arginine catabolic process to spermine	The chemical reactions and pathways resulting in the breakdown of arginine into other compounds, including spermine.	tmpzr1t_l9r_go_relaxed.owl	arginine degradation to spermine|arginine breakdown to spermine				MetaCyc:ARGSPECAT-PWY									biological_process											owl:Class	
GO:0070096	biolink:NamedThing	mitochondrial outer membrane translocase complex assembly	The aggregation, arrangement and bonding together of a set of components to form a mitochondrial outer membrane translocase complex.	tmpzr1t_l9r_go_relaxed.owl	TOM complex assembly|mitochondrion outer membrane translocase complex assembly													biological_process											owl:Class	
GO:0038163	biolink:NamedThing	thrombopoietin-mediated signaling pathway	A series of molecular signals initiated by the binding of a thrombopoietin to the thrombopoietin receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.	tmpzr1t_l9r_go_relaxed.owl	THPO signaling pathway|thrombopoietin receptor signaling pathway|THPO/MPL signaling pathway							bf	2012-05-14T02:45:53Z					biological_process											owl:Class	
GO:0070355	biolink:NamedThing	synaptotagmin-synaptobrevin 2-SNAP-25-syntaxin-1a-syntaxin-1b-Rab3a-complexin II complex	A SNARE complex that contains synaptotagmin, synaptobrevin 2 (VAMP2), SNAP-25, syntaxin 1a, syntaxin1b, Rab3a, and complexin II (or orthologs thereof).	tmpzr1t_l9r_go_relaxed.owl	STX1a-STX1b-SNAP25-RAB3a-SYT1-VAMP2-CPLX2 complex|SNARE complex (STX1a, STX1b, SNAP25, RAB3a, SYT1, VAMP2, CPLX2)													cellular_component											owl:Class	
GO:1903493	biolink:NamedThing	response to clopidogrel	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a clopidogrel stimulus. Clopidogrel is a is an oral, thienopyridine-class antiplatelet agent used to inhibit blood clots in coronary artery disease, peripheral vascular disease, and cerebrovascular disease.	tmpzr1t_l9r_go_relaxed.owl								hp	2014-09-25T11:36:42Z					biological_process											owl:Class	
GO:0097392	biolink:NamedThing	chemokine (C-X-C motif) ligand 16 production	The appearance of chemokine (C-X-C motif) ligand 16 (CXCL16) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	tmpzr1t_l9r_go_relaxed.owl	CXCL16 production							pr	2012-10-23T07:59:43Z					biological_process											owl:Class	
GO:0045299	biolink:NamedThing	otolith mineralization	The precipitation of specific crystal forms of calcium carbonate with extracellular matrix proteins in the otolith organs of the vertebrate inner ear.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0071399	biolink:NamedThing	cellular response to linoleic acid	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a linoleic acid stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to linoleate							mah	2009-12-11T04:40:22Z					biological_process											owl:Class	
GO:0102224	biolink:NamedThing	GDP-2,4-diacetamido-2,4,6-trideoxy-alpha-D-glucopyranose hydrolase/2-epimerase activity	Catalysis of the reaction: GDP-2,4-diacetamido-2,4,6-trideoxy-alpha-D-glucopyranose + H2O <=> 2,4-diacetamido-2,4,6-trideoxy-alpha-D-mannopyranose + GDP + H+.	tmpzr1t_l9r_go_relaxed.owl					RHEA:46316|MetaCyc:RXN-12236									molecular_function											owl:Class	
GO:0061667	biolink:NamedThing	URM1 ligase activity	Catalysis of the transfer of URM1 to a substrate protein via the reaction X-URM1 + S --> X + S-URM1, where X is either an E2 or E3 enzyme, the X-URM1 linkage is a thioester bond, and the S-URM1 linkage is an isopeptide bond between the C-terminal amino acid of URM1 and the epsilon-amino group of lysine residues in the substrate.	tmpzr1t_l9r_go_relaxed.owl	E3							dph	2014-11-06T14:04:43Z					molecular_function											owl:Class	
GO:0090253	biolink:NamedThing	convergent extension involved in imaginal disc-derived wing morphogenesis	The morphogenetic process in which the wing epithelium narrows along one axis and lengthens in a perpendicular axis that contributes to imaginal disc-derived wing morphogenesis.	tmpzr1t_l9r_go_relaxed.owl								tb	2010-01-22T11:40:46Z					biological_process											owl:Class	
GO:1904850	biolink:NamedThing	negative regulation of establishment of protein localization to telomere	Any process that stops, prevents or reduces the frequency, rate or extent of establishment of protein localization to telomere.	tmpzr1t_l9r_go_relaxed.owl	inhibition of establishment of protein localisation to telomere|down-regulation of establishment of protein localization to telomere|down-regulation of establishment of protein localization to chromosome, telomeric region|down regulation of establishment of protein localization to chromosome, telomeric region|inhibition of establishment of protein localization to telomere|negative regulation of establishment of protein localisation to telomere|downregulation of establishment of protein localisation to telomere|negative regulation of establishment of protein localization to chromosome, telomeric region|down-regulation of establishment of protein localisation to telomere|downregulation of establishment of protein localization to chromosome, telomeric region|downregulation of establishment of protein localization to telomere|inhibition of establishment of protein localization to chromosome, telomeric region|down regulation of establishment of protein localisation to telomere|down regulation of establishment of protein localization to telomere							nc	2015-12-10T15:37:51Z					biological_process											owl:Class	
GO:0090602	biolink:NamedThing	sieve element enucleation	The process in which nucleated precursor cells lose their nucleus as part of sieve element differentiation. The nuclear contents are released and degraded in the cytoplasm at the same time as other organelles are rearranged and the cytosol is degraded.	tmpzr1t_l9r_go_relaxed.owl								tb	2014-09-05T16:25:16Z					biological_process											owl:Class	
GO:0017179	biolink:NamedThing	peptidyl-diphthine metabolic process	The chemical reactions and pathways involving peptidyl-diphthine, a modified histidine residue.	tmpzr1t_l9r_go_relaxed.owl	peptidyl-diphthine metabolism													biological_process											owl:Class	
GO:0052576	biolink:NamedThing	carbohydrate storage	The accumulation and maintenance in cells or tissues of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y.	tmpzr1t_l9r_go_relaxed.owl									2010-07-23T04:16:56Z					biological_process											owl:Class	
GO:0150094	biolink:NamedThing	amyloid-beta clearance by cellular catabolic process	The process in which amyloid-beta is removed from extracellular brain regions by cell surface receptor-mediated endocytosis, followed by intracellular degradation.	tmpzr1t_l9r_go_relaxed.owl	amyloid-beta clearance by phagocytosis							bc	2018-08-16T14:38:09Z					biological_process											owl:Class	
GO:0106223	biolink:NamedThing	germacrene A hydroxylase activity	Catalysis of the reaction:(+)-(R)-germacrene A + 3 O2 + 3 reduced [NADPH--hemoprotein reductase] = germacra-1(10),4,11(13)-trien-12-oate + 4 H(+) + 4 H2O + 3 oxidized [NADPH--hemoprotein reductase].	tmpzr1t_l9r_go_relaxed.owl	germacrene A alcohol dehydrogenase activity	https://github.com/geneontology/go-ontology/issues/21412			EC:1.14.14.95|MetaCyc:RXN-12449|RHEA:30303	Formerly EC:1.1.1.314.		hjd	2019-09-06T16:36:25Z			GO:0102260		molecular_function											owl:Class	
GO:0018729	biolink:NamedThing	propionate CoA-transferase activity	Catalysis of the reaction: acetyl-CoA + propanoate = acetate + propanoyl-CoA.	tmpzr1t_l9r_go_relaxed.owl	propionyl-CoA transferase activity|propionate-CoA:lactoyl-CoA transferase activity|propionate coenzyme A-transferase activity|propionyl CoA:acetate CoA transferase activity|acetyl-CoA:propanoate CoA-transferase activity				RHEA:23520|EC:2.8.3.1|UM-BBD_reactionID:r0087|MetaCyc:PROPIONATE-COA-TRANSFERASE-RXN									molecular_function											owl:Class	
GO:0050487	biolink:NamedThing	sulfoacetaldehyde acetyltransferase activity	Catalysis of the reaction: acetyl phosphate + sulfite = phosphate + sulfoacetaldehyde.	tmpzr1t_l9r_go_relaxed.owl	sulphoacetaldehyde acetyltransferase activity|acetyl-phosphate:sulfite S-acetyltransferase (acyl-phosphate hydrolysing, 2-oxoethyl-forming)				EC:2.3.3.15|KEGG_REACTION:R05651|MetaCyc:RXN-2364|RHEA:24204	Note that the enzyme sulfoacetaldehyde acetyltransferase also has sulfoacetaldehyde lyase activity (GO:0050312).								molecular_function											owl:Class	
GO:0030115	biolink:NamedThing	S-layer	A crystalline protein layer surrounding some bacteria.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:S-layer									cellular_component											owl:Class	
GO:0016205	biolink:NamedThing	selenocysteine methyltransferase activity	Catalysis of the reaction: selenocysteine + S-adenosyl-L-methionine = Se-methylselenocysteine + S-adenosyl-homocysteine.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-11061|RHEA:26341|EC:2.1.1.280									molecular_function											owl:Class	
GO:1903374	biolink:NamedThing	subarachnoid space development	The process whose specific outcome is the progression of a subarachnoid space over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl	spatium subarachnoideum development|subarachnoid cavity development|cavum subarachnoideale development|cavitas subarachnoidea development|spatium leptomeningeum development	https://github.com/geneontology/go-ontology/issues/21883						pr	2014-08-22T12:20:56Z					biological_process											owl:Class	
GO:0050294	biolink:NamedThing	steroid sulfotransferase activity	Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + a phenolic steroid = adenosine 3',5'-bisphosphate + steroid O-sulfate.	tmpzr1t_l9r_go_relaxed.owl	steroid sulphotransferase activity|steroid alcohol sulfotransferase|3'-phosphoadenylyl-sulfate:phenolic-steroid sulfotransferase activity				Reactome:R-HSA-176631|Reactome:R-HSA-176517|Reactome:R-HSA-176521|EC:2.8.2.15|MetaCyc:STEROID-SULFOTRANSFERASE-RXN									molecular_function											owl:Class	
GO:0018634	biolink:NamedThing	alpha-pinene monooxygenase [NADH] activity	Catalysis of the reaction: alpha-pinene + NADH + H+ + O2 = NAD+ + H2O + alpha-pinene oxide.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0742|EC:1.14.13.-									molecular_function											owl:Class	
GO:0106400	biolink:NamedThing	double-strand break repair via transcription-associated homologous recombination	A mechanism of homologous recombination and DNA repair in which transcript RNA is used as a template for DSB repair.	tmpzr1t_l9r_go_relaxed.owl								hjd	2021-10-11T20:48:06Z					biological_process											owl:Class	
GO:0102075	biolink:NamedThing	OPC4-trans-2-enoyl-CoA hydratase activity	Catalysis of the reaction: OPC4-3-hydroxyacyl-CoA <=> OPC4-trans-2-enoyl-CoA + H2O.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-10705									molecular_function											owl:Class	
GO:0018968	biolink:NamedThing	tetrahydrofuran metabolic process	The chemical reactions and pathways involving tetrahydrofuran, a cyclic 4 carbon ether. It is one of the most polar ethers and is a widely used solvent for polar reagents. Since THF is very soluble in water and has a relatively low boiling point, significant amounts are often released into the environment, causing contamination problems.	tmpzr1t_l9r_go_relaxed.owl	THF metabolism|THF metabolic process|tetrahydrofuran metabolism				UM-BBD_pathwayID:thf									biological_process											owl:Class	
GO:0019264	biolink:NamedThing	glycine biosynthetic process from serine	The chemical reactions and pathways resulting in the formation of glycine from other compounds, including serine.	tmpzr1t_l9r_go_relaxed.owl	glycine formation from serine|glycine synthesis from serine|glycine anabolism from serine				MetaCyc:GLYSYN-PWY									biological_process											owl:Class	
GO:0097754	biolink:NamedThing	clathrin-mediated membrane bending	A membrane bending process mediated by clathrin.	tmpzr1t_l9r_go_relaxed.owl								pr	2017-01-25T16:38:42Z					biological_process											owl:Class	
GO:0098683	biolink:NamedThing	cochlear hair cell ribbon synapse	A ribbon synpase of an auditory hair cell of the cochlear. These ribbon synapses contain spherical synaptic ribbons and lack and arciform density.	tmpzr1t_l9r_go_relaxed.owl								dos	2017-02-05T16:16:49Z					cellular_component											owl:Class	
GO:0097470	biolink:NamedThing	ribbon synapse	Type of synapse characterized by an electron-dense ribbon, lamella (bar) or spherical body in the presynaptic process cytoplasm.	tmpzr1t_l9r_go_relaxed.owl	synapsis fasciolaris				NIF_Subcellular:sao1884931180			pr	2013-02-21T07:40:01Z					cellular_component											owl:Class	
GO:0106250	biolink:NamedThing	DNA-binding transcription repressor activity, RNA polymerase III-specific	A DNA-binding transcription factor activity that represses or decreases the transcription of specific genes sets transcribed by RNA polymerase III.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/20253				For usage guidance, see comment in GO:0003700 ; DNA-binding transcription factor activity.		hjd	2020-02-19T19:34:18Z					molecular_function											owl:Class	
GO:0000332	biolink:NamedThing	template for synthesis of G-rich strand of telomere DNA activity	Provision of the template used by reverse transcriptase to synthesize the G-rich strand of telomeric DNA.	tmpzr1t_l9r_go_relaxed.owl	telomerase, template|telomerase RNA					Note that this term describes the activity of an RNA gene product that interacts with other nucleic acid molecules via base pairing; it should not be used to annotate proteins.								molecular_function											owl:Class	
GO:0102156	biolink:NamedThing	2,5-DHBA UDP-glucosyltransferase activity	Catalysis of the reaction: 2,5-dihydroxybenzoate + UDP-alpha-D-glucose <=> 2,5-dihydroxybenzoate 5-O-beta-D-glucoside + UDP + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-11705									molecular_function											owl:Class	
GO:0031752	biolink:NamedThing	D5 dopamine receptor binding	Binding to a D5 dopamine receptor.	tmpzr1t_l9r_go_relaxed.owl	D5 dopamine receptor ligand|D1B dopamine receptor binding													molecular_function											owl:Class	
GO:0017172	biolink:NamedThing	cysteine dioxygenase activity	Catalysis of the reaction: L-cysteine + O(2) = 3-sulfino-L-alanine + H(+).	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:CYSTEINE-DIOXYGENASE-RXN|Reactome:R-HSA-1614645|EC:1.13.11.20|RHEA:20441|KEGG_REACTION:R00893									molecular_function											owl:Class	
GO:0090574	biolink:NamedThing	RNA polymerase V transcription repressor complex	A protein complex, located in the nucleus, that possesses activity that prevents or downregulates transcription from a RNA polymerase V promoter.	tmpzr1t_l9r_go_relaxed.owl								tb	2014-05-09T13:26:16Z					cellular_component											owl:Class	
GO:0042105	biolink:NamedThing	alpha-beta T cell receptor complex	A T cell receptor complex in which the TCR heterodimer comprises alpha and beta chains, associated with the CD3 complex; recognizes a complex consisting of an antigen-derived peptide bound to a class I or class II MHC protein.	tmpzr1t_l9r_go_relaxed.owl	alpha-beta T lymphocyte receptor complex|alpha-beta T-cell receptor complex|alpha-beta T-lymphocyte receptor complex|alpha-beta TCR complex													cellular_component											owl:Class	
GO:0047868	biolink:NamedThing	dimethylmaleate hydratase activity	Catalysis of the reaction: (2R,3S)-2,3-dimethylmalate = dimethylmaleate + H(2)O.	tmpzr1t_l9r_go_relaxed.owl	(2R,3S)-2,3-dimethylmalate hydro-lyase (dimethylmaleate-forming)|(2R,3S)-2,3-dimethylmalate hydro-lyase activity				RHEA:20253|KEGG_REACTION:R03069|MetaCyc:DIMETHYLMALEATE-HYDRATASE-RXN|EC:4.2.1.85									molecular_function											owl:Class	
GO:0106217	biolink:NamedThing	tRNA C3-cytosine methylation	The process whereby a cytosine in a tRNA is methylated at position 3 of the cytosine.	tmpzr1t_l9r_go_relaxed.owl								hjd	2019-07-19T19:52:40Z					biological_process											owl:Class	
GO:0016340	biolink:NamedThing	calcium-dependent cell-matrix adhesion	The binding of a cell to the extracellular matrix via adhesion molecules that require the presence of calcium for the interaction.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0047955	biolink:NamedThing	glycerol dehydrogenase (acceptor) activity	Catalysis of the reaction: A + glycerol = AH(2) + glycerone.	tmpzr1t_l9r_go_relaxed.owl	glycerol:(acceptor) 1-oxidoreductase activity|glycerol:acceptor 1-oxidoreductase activity				EC:1.1.99.22|MetaCyc:GLYCEROL-DEHYDROGENASE-ACCEPTOR-RXN|RHEA:17493|KEGG_REACTION:R01045									molecular_function											owl:Class	
GO:0089716	biolink:NamedThing	Pip2-Oaf1 complex	A heterodimeric complex consisting of Zn(2)Cys(6) containing transcription factors Pip2 and Oaf1. It binds to the oleate response element (ORE), found in the promoters of fatty acid-inducible genes in Saccharomyces where, in the presence of oleate this bound complex activates the transcription of genes encoding peroxisomal proteins.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0102252	biolink:NamedThing	cellulose 1,4-beta-cellobiosidase activity (reducing end)	Catalysis of the reaction: n H2O + a cellodextrin = n beta-cellobiose, releasing cellobiose from the reducing ends of the chains.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-12420|EC:3.2.1.176									molecular_function											owl:Class	
GO:0004903	biolink:NamedThing	growth hormone receptor activity	Combining with a growth hormone and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0042649	biolink:NamedThing	prothylakoid	Underdeveloped thylakoids found in etioplasts, lacking competent photosynthetic membranes. Rapidly develop into mature thylakoids in the presence of light.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0033973	biolink:NamedThing	dCTP deaminase (dUMP-forming) activity	Catalysis of the reaction: dCTP + 2 H(2)O = diphosphate + dUMP + H(+) + NH(4)(+).	tmpzr1t_l9r_go_relaxed.owl	dCTP aminohydrolase (dUMP-forming) activity				EC:3.5.4.30|MetaCyc:3.5.4.30-RXN|RHEA:19205|KEGG_REACTION:R07307									molecular_function											owl:Class	
GO:0035370	biolink:NamedThing	UBC13-UEV1A complex	A heterodimeric ubiquitin conjugating enzyme complex that catalyzes assembly of K63-linked polyubiquitin chains and is involved in NF-kappaB activation. In humans at least, the complex comprises the ubiquitin-conjugating enzyme UBC13 and ubiquitin-conjugating enzyme variant 1A (UEV1A).	tmpzr1t_l9r_go_relaxed.owl								bf	2010-03-11T10:53:09Z					cellular_component											owl:Class	
GO:0033825	biolink:NamedThing	oligosaccharide 4-alpha-D-glucosyltransferase activity	Catalysis of the transfer of the non-reducing terminal alpha-D-glucose residue from a 1,4-alpha-D-glucan to the 4-position of an alpha-D-glucan, thus bringing about the hydrolysis of oligosaccharides.	tmpzr1t_l9r_go_relaxed.owl	1,4-alpha-D-glucan:1,4-alpha-D-glucan 4-alpha-D-glucosyltransferase activity|1,4-alpha-glucan:1,4-alpha-glucan 4-alpha-glucosyltransferase activity|amylase III activity				EC:2.4.1.161|MetaCyc:2.4.1.161-RXN									molecular_function											owl:Class	
GO:0051698	biolink:NamedThing	saccharopine oxidase activity	Catalysis of the reaction: L-saccharopine + O2 = L-2-aminoadipic 6-semialdehyde + L-glutamate + H2O2.	tmpzr1t_l9r_go_relaxed.owl	SAX activity													molecular_function											owl:Class	
GO:0032578	biolink:NamedThing	aleurone grain membrane	The lipid bilayer surrounding an aleurone grain.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0071990	biolink:NamedThing	maintenance of protein location to spindle pole body	Any process in which a protein is maintained in a specific location at the spindle pole body, and is prevented from moving elsewhere.	tmpzr1t_l9r_go_relaxed.owl	maintenance of protein location in spindle pole body|maintenance of protein location at spindle pole body							mah	2010-10-25T11:02:31Z					biological_process											owl:Class	
GO:0005176	biolink:NamedThing	ErbB-2 class receptor binding	Binding to a protein-tyrosine kinase receptor Neu/ErbB-2/HER2.	tmpzr1t_l9r_go_relaxed.owl	ErbB-2 class receptor ligand|Neu receptor ligand|HER2 receptor ligand|Neu receptor binding|HER2 receptor binding													molecular_function											owl:Class	
GO:0043373	biolink:NamedThing	CD4-positive, alpha-beta T cell lineage commitment	The process in which an immature T cell becomes committed to becoming a CD4-positive, alpha-beta T cell.	tmpzr1t_l9r_go_relaxed.owl	CD4-positive, alpha-beta T lymphocyte lineage commitment|CD4-positive, alpha-beta T-lymphocyte lineage commitment|CD4-positive, alpha-beta T-cell lineage commitment													biological_process											owl:Class	
GO:0061573	biolink:NamedThing	actin filament bundle retrograde transport	A process of actin filament bundle distribution that results in the arrangement of actin filament bundles from the periphery toward the interior of the cell.	tmpzr1t_l9r_go_relaxed.owl	actin filament cable retrograde transport							dph	2013-08-02T11:31:04Z					biological_process											owl:Class	
GO:0033913	biolink:NamedThing	glucan endo-1,2-beta-glucosidase activity	Catalysis of the random hydrolysis of (1->2)-glucosidic linkages in (1->2)-beta-D-glucans.	tmpzr1t_l9r_go_relaxed.owl	endo-(1->2)-beta-D-glucanase activity|1,2-beta-D-glucan glucanohydrolase activity|endo-1,2-beta-glucanase activity|beta-D-1,2-glucanase activity				MetaCyc:3.2.1.71-RXN|EC:3.2.1.71									molecular_function											owl:Class	
GO:0090358	biolink:NamedThing	positive regulation of tryptophan metabolic process	Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving tryptophan, the chiral amino acid 2-amino-3-(1H-indol-3-yl)propanoic acid.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of tryptophan metabolism							tb	2010-06-29T02:38:48Z					biological_process											owl:Class	
GO:0102916	biolink:NamedThing	sesamin synthase activity	Catalysis of the reaction: H+ + (+)-piperitol + NADPH + O2 <=> (+)-sesamin + NADP + 2 H2O.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-8696|EC:1.14.19.74									molecular_function											owl:Class	
GO:0010283	biolink:NamedThing	pinoresinol reductase activity	Catalysis of the reaction: pinoresinol + NADPH + H+ = lariciresinol + NADP+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-8683|MetaCyc:RXN-8678									molecular_function											owl:Class	
GO:0018233	biolink:NamedThing	peptide cross-linking via 2'-(S-L-cysteinyl)-L-histidine	The modification of peptidyl-histidine and peptidyl-cysteine to form a 2'-(S-L-cysteinyl)-L-histidine protein cross-link.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0109									biological_process											owl:Class	
GO:0046588	biolink:NamedThing	negative regulation of calcium-dependent cell-cell adhesion	Any process that stops, prevents, or reduces the frequency, rate or extent of calcium-dependent cell-cell adhesion.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of calcium-dependent cell-cell adhesion|inhibition of calcium-dependent cell-cell adhesion|down regulation of calcium-dependent cell-cell adhesion|downregulation of calcium-dependent cell-cell adhesion													biological_process											owl:Class	
GO:0072559	biolink:NamedThing	NLRP3 inflammasome complex	An inflammasome complex that consists of three components, NLRP3 (NALP3), PYCARD and caspase-1. It is activated upon exposure to whole pathogens, as well as a number of structurally diverse pathogen- and danger-associated molecular patterns (PAMPs and DAMPs) and environmental irritants. Whole pathogens demonstrated to activate the NLRP3 inflammasome complex include the fungi Candida albicans and Saccharomyces cerevisiae, bacteria that produce pore-forming toxins, including Listeria monocytogenes and Staphylococcus aureus, and viruses such as Sendai virus, adenovirus, and influenza virus.	tmpzr1t_l9r_go_relaxed.owl	NALP3 inflammasome complex							mah	2011-01-27T12:04:30Z					cellular_component											owl:Class	
GO:0075219	biolink:NamedThing	modulation of zoospore encystment on host	Any process that modulates the frequency, rate or extent of zoospore encystment on host. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0032794	biolink:NamedThing	GTPase activating protein binding	Binding to a GTPase activating protein.	tmpzr1t_l9r_go_relaxed.owl	GAP binding													molecular_function											owl:Class	
GO:0004063	biolink:NamedThing	aryldialkylphosphatase activity	Catalysis of the reaction: aryl dialkyl phosphate + H2O = dialkyl phosphate + an aryl alcohol.	tmpzr1t_l9r_go_relaxed.owl	A-esterase activity|esterase B1|phosphotriesterase activity|organophosphate hydrolase activity|paraoxon hydrolase activity|esterase E4|pirimiphos-methyloxon esterase activity|paraoxon esterase activity|OPH|paraoxonase activity|organophosphorus hydrolase activity|organophosphorus acid anhydrase activity|aryltriphosphate dialkylphosphohydrolase activity|aryltriphosphatase activity|organophosphate esterase activity				UM-BBD_enzymeID:e0054|RHEA:18053|MetaCyc:ARYLDIALKYLPHOSPHATASE-RXN|EC:3.1.8.1									molecular_function											owl:Class	
GO:0023059	biolink:NamedThing	positive adaptation of signaling pathway	The positive regulation of a signal transduction pathway in response to a stimulus upon prolonged exposure to that stimulus.	tmpzr1t_l9r_go_relaxed.owl	positive adaptation of signalling pathway								2010-02-16T09:30:50Z					biological_process											owl:Class	
GO:0023058	biolink:NamedThing	adaptation of signaling pathway	The regulation of a signal transduction pathway in response to a stimulus upon prolonged exposure to that stimulus.	tmpzr1t_l9r_go_relaxed.owl	adaptation of signalling pathway								2010-02-16T09:30:50Z					biological_process											owl:Class	
GO:0097706	biolink:NamedThing	vascular endothelial cell response to oscillatory fluid shear stress	Any response to oscillatory fluid shear stress that occurs in a vascular endothelial cell.	tmpzr1t_l9r_go_relaxed.owl	blood vessel endothelial cell response to oscillatory fluid shear stress							pr	2016-01-27T14:25:34Z					biological_process											owl:Class	
GO:0097704	biolink:NamedThing	cellular response to oscillatory fluid shear stress	Any response to oscillatory fluid shear stress that occurs at the level of a cell.	tmpzr1t_l9r_go_relaxed.owl								pr	2016-01-27T14:20:54Z					biological_process											owl:Class	
GO:0038003	biolink:NamedThing	G protein-coupled opioid receptor signaling pathway	The series of molecular signals generated as a consequence of an opioid receptor binding to one of its physiological ligands.	tmpzr1t_l9r_go_relaxed.owl	opioid receptor signalling pathway|opioid receptor signaling pathway	https://github.com/geneontology/go-ontology/issues/21110			Wikipedia:Opioid_receptor			bf	2011-03-03T02:00:02Z					biological_process											owl:Class	
GO:0061821	biolink:NamedThing	telomeric D-loop binding	Binding to a telomeric D-loop. A telomeric D-loop is a three-stranded DNA displacement loop that forms at the site where the telomeric 3' single-stranded DNA overhang (formed of the repeat sequence TTAGGG in mammals) is tucked back inside the double-stranded component of telomeric DNA molecule, thus forming a t-loop or telomeric-loop and protecting the chromosome terminus.	tmpzr1t_l9r_go_relaxed.owl	telomeric Displacement-loop binding							dph						molecular_function											owl:Class	
GO:0010236	biolink:NamedThing	plastoquinone biosynthetic process	The chemical reactions and pathways resulting in the formation of plastoquinone, a lipid-soluble electron-transporting coenzyme present in the chloroplast.	tmpzr1t_l9r_go_relaxed.owl	plastoquinone biosynthesis|plastoquinone synthesis|plastoquinone formation|plastoquinone anabolism				MetaCyc:PWY-1581									biological_process											owl:Class	
GO:0015221	biolink:NamedThing	lipopolysaccharide transmembrane transporter activity	Enables the transfer of lipopolysaccharides from one side of a membrane to the other. A lipopolysaccharide is any of a group of related, structurally complex components of the outer membrane of Gram-negative bacteria. Lipopolysaccharides consist three covalently linked regions, lipid A, core oligosaccharide, and an O side chain. Lipid A is responsible for the toxicity of the lipopolysaccharide.	tmpzr1t_l9r_go_relaxed.owl	LPS transmembrane transporter activity													molecular_function											owl:Class	
GO:0043692	biolink:NamedThing	monoterpene metabolic process	The chemical reactions and pathways involving monoterpenes, terpenes with a C10 structure.	tmpzr1t_l9r_go_relaxed.owl	monoterpene metabolism													biological_process											owl:Class	
GO:0033822	biolink:NamedThing	glucosyl-DNA beta-glucosyltransferase activity	Catalysis of the transfer of a beta-D-glucosyl residue from UDP-glucose to a glucosylhydroxymethylcytosine residue in DNA.	tmpzr1t_l9r_go_relaxed.owl	UDP-glucose:D-glucosyl-DNA beta-D-glucosyltransferase activity|UDPglucose:D-glucosyl-DNA beta-D-glucosyltransferase activity|uridine diphosphoglucose-glucosyldeoxyribonucleate beta-glucosyltransferase activity|T6-beta-glucosyl transferase activity|T6-glucosyl-HMC-beta-glucosyl transferase activity				EC:2.4.1.28|MetaCyc:2.4.1.28-RXN									molecular_function											owl:Class	
GO:0000101	biolink:NamedThing	sulfur amino acid transport	The directed movement of amino acids containing sulfur (cystine, methionine and their derivatives) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	sulphur amino acid transport													biological_process											owl:Class	
GO:0051089	biolink:NamedThing	constitutive protein ectodomain proteolysis	The proteolytic cleavage of transmembrane proteins and release of their ectodomain that occurs constantly, regardless of environmental conditions or demands.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0039553	biolink:NamedThing	suppression by virus of host chemokine activity	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host chemokine activity.	tmpzr1t_l9r_go_relaxed.owl	inhibition of host chemokines by virus|inhibition by virus of host chemokine activity|downregulation by virus of host chemokine activity|negative regulation by virus of host chemokine activity|down-regulation by virus of host chemokine activity				VZ:813			bf	2012-02-28T01:29:55Z					biological_process											owl:Class	
GO:0039518	biolink:NamedThing	suppression by virus of host cytokine activity	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host cytokine activity.	tmpzr1t_l9r_go_relaxed.owl	down-regulation by virus of host cytokine activity|inhibition by virus of host cytokine activity|downregulation by virus of host cytokine activity|negative regulation by virus of host cytokine activity							bf	2011-06-22T04:09:41Z					biological_process											owl:Class	
GO:0004642	biolink:NamedThing	phosphoribosylformylglycinamidine synthase activity	Catalysis of the reaction: N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide + L-glutamine + ATP + H(2)O = 2-(formamido)-N(1)-(5-phospho-D-ribosyl)acetamidine + L-glutamate + ADP + 2 H(+) + phosphate.	tmpzr1t_l9r_go_relaxed.owl	2-N-formyl-1-N-(5-phospho-D-ribosyl)glycinamide:L-glutamine amido-ligase (ADP-forming)|FGAR amidotransferase activity|phosphoribosylformylglycinamidine synthetase activity|FGAM synthase activity|formylglycinamide ribotide amidotransferase activity|formylglycinamide ribonucloetide amidotransferase activity|FGAM synthetase activity|FGARAT activity|phosphoribosylformylglycineamidine synthetase activity|5'-phosphoribosylformylglycinamide:L-glutamine amido-ligase (ADP-forming)|N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide:L-glutamine amido-ligase (ADP-forming)				KEGG_REACTION:R04463|EC:6.3.5.3|RHEA:17129|Reactome:R-HSA-73812|MetaCyc:FGAMSYN-RXN									molecular_function											owl:Class	
GO:1901853	biolink:NamedThing	5,6,7,8-tetrahydrosarcinapterin metabolic process	The chemical reactions and pathways involving 5,6,7,8-tetrahydrosarcinapterin.	tmpzr1t_l9r_go_relaxed.owl	5,6,7,8-tetrahydrosarcinapterin metabolism							yaf	2013-01-28T11:47:52Z					biological_process											owl:Class	
GO:0045776	biolink:NamedThing	negative regulation of blood pressure	Any process in which the force of blood traveling through the circulatory system is decreased.	tmpzr1t_l9r_go_relaxed.owl	down regulation of blood pressure|inhibition of blood pressure|down-regulation of blood pressure|downregulation of blood pressure													biological_process											owl:Class	
GO:0051912	biolink:NamedThing	CoB--CoM heterodisulfide reductase activity	Catalysis of the reaction: coenzyme B + coenzyme M + methanophenazine = N-{7-[(2-sulfoethyl)dithio]heptanoyl}-3-O-phospho-L-threonine + dihydromethanophenazine.	tmpzr1t_l9r_go_relaxed.owl	coenzyme B--coenzyme M heterodisulfide reductase activity|soluble heterodisulfide reductase activity|CoB-CoM heterodisulfide reductase activity|coenzyme-M-7-mercaptoheptanoylthreonine-phosphate-heterodisulfide hydrogenase activity|heterodisulfide reductase activity|coenzyme B:coenzyme M:methanophenazine oxidoreductase activity				MetaCyc:1.8.98.1-RXN|EC:1.8.98.1|RHEA:18085									molecular_function											owl:Class	
GO:0070353	biolink:NamedThing	GATA1-TAL1-TCF3-Lmo2 complex	A protein complex that contains the zinc finger transcription factor GATA1, the LIM domain protein Lmo2 (RBTN2), the basic helix-loop-helix protein TAL1 and its binding partner TCF3. The complex is involved transcriptional regulation in hematopoiesis.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0099619	biolink:NamedThing	UDP-4-amino-4-deoxy-L-arabinose formyltransferase activity	Catalysis of the reaction: 10-formyltetrahydrofolate + UDP-4-amino-4-deoxy-beta-L-arabinopyranose = 5,6,7,8-tetrahydrofolate + UDP-4-deoxy-4-formamido-beta-L-arabinopyranose.	tmpzr1t_l9r_go_relaxed.owl	10-formyltetrahydrofolate:UDP-4-amino-4-deoxy-beta-L-arabinose N-formyltransferase activity|UDP-L-Ara4N formyltransferase activity|ArnAFT activity				EC:2.1.2.13|RHEA:24706									molecular_function											owl:Class	
GO:0048149	biolink:NamedThing	behavioral response to ethanol	Any process that results in a change in the behavior of an organism as a result of an ethanol stimulus.	tmpzr1t_l9r_go_relaxed.owl	behavioural response to ethanol													biological_process											owl:Class	
GO:0045599	biolink:NamedThing	negative regulation of fat cell differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of adipocyte differentiation.	tmpzr1t_l9r_go_relaxed.owl	inhibition of fat cell differentiation|negative regulation of adipocyte differentiation|negative regulation of adipocyte cell differentiation|down-regulation of fat cell differentiation|down regulation of fat cell differentiation|downregulation of fat cell differentiation													biological_process											owl:Class	
GO:0061543	biolink:NamedThing	3-demethylubiquinol-6 3-O-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + 3-demethylubiquinol-6 = S-adenosyl-L-homocysteine + ubiquinol-6.	tmpzr1t_l9r_go_relaxed.owl								dph	2013-06-25T08:05:14Z					molecular_function											owl:Class	
GO:0071074	biolink:NamedThing	eukaryotic initiation factor eIF2 binding	Binding to eukaryotic initiation factor eIF2, a protein complex involved in the initiation of ribosome-mediated translation.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-11-06T01:39:02Z					molecular_function											owl:Class	
GO:0000348	biolink:NamedThing	mRNA branch site recognition	Recognition of the pre-mRNA branch site sequence by components of the assembling spliceosome.	tmpzr1t_l9r_go_relaxed.owl	nuclear mRNA branch site recognition|spliceosomal B complex biosynthesis|U12-type nuclear mRNA branch site recognition|spliceosomal B complex formation|U2-type nuclear mRNA branch site recognition|spliceosomal A complex biosynthesis|spliceosomal A complex formation					Note that this step represents the formation of the B complex (yeast) or the A complex (mammalian).						GO:0000371|GO:0000370		biological_process											owl:Class	
GO:0021791	biolink:NamedThing	chemoattraction of branchiomotor neuron axon in branchial arch mesenchyme	The process in which a branchiomotor neuron growth cone in the branchial arch mesenchyme is directed to a specific target site in the branchial arch mesenchyme in response to an attractive chemical cue. Branchiomotor neurons are located in the hindbrain and innervate branchial arch-derived muscles that control jaw movements, facial expression, the larynx, and the pharynx.	tmpzr1t_l9r_go_relaxed.owl	positive chemotaxis of branchiomotor neuron axon in branchial arch mesenchyme													biological_process											owl:Class	
GO:0021789	biolink:NamedThing	branchiomotor neuron axon guidance in branchial arch mesenchyme	The process in which a branchiomotor neuron growth cone in the branchial arch mesenchyme is directed to a specific target site in the branchial arch mesenchyme. Branchiomotor neurons are located in the hindbrain and innervate branchial arch-derived muscles that control jaw movements, facial expression, the larynx, and the pharynx.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0010716	biolink:NamedThing	negative regulation of extracellular matrix disassembly	Any process that decreases the rate, frequency or extent of extracellular matrix disassembly. Extracellular matrix disassembly is a process that results in the breakdown of the extracellular matrix.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of extracellular matrix disassembly|negative regulation of extracellular matrix degradation|down regulation of extracellular matrix disassembly|downregulation of extracellular matrix disassembly|negative regulation of extracellular matrix breakdown|inhibition of extracellular matrix disassembly													biological_process											owl:Class	
GO:0052672	biolink:NamedThing	CTP:geranylgeraniol kinase activity	Catalysis of the reaction: geranylgeraniol + CTP = all-trans-geranyl-geranyl monophosphate + CDP.	tmpzr1t_l9r_go_relaxed.owl	CTP:geranylgeraniol phosphotransferase activity				EC:2.7.1.216|MetaCyc:RXN-11629			ai	2011-04-11T03:26:04Z					molecular_function											owl:Class	
GO:0070336	biolink:NamedThing	flap-structured DNA binding	Binding to a flap structure in DNA. A DNA flap structure is one in which a single-stranded length of DNA or RNA protrudes from a double-stranded DNA molecule.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0097454	biolink:NamedThing	Schwann cell microvillus	Small finger-like extension of a Schwann cell that contacts the nodal membrane.	tmpzr1t_l9r_go_relaxed.owl					NIF_Subcellular:sao1890444066			pr	2012-12-19T13:01:02Z					cellular_component											owl:Class	
GO:0031411	biolink:NamedThing	gas vesicle	An intracellular non-membrane-bounded organelle; a hollow structure made of protein, which usually has the form of a cylindrical tube closed by conical end caps. By regulating their relative gas vesicle content, aquatic microbes are able to perform vertical migrations.	tmpzr1t_l9r_go_relaxed.owl	gas vacuole					Note that although this organelle is commonly referred to as a 'vesicle' or 'vacuole' in the literature, it is not surrounded by a membrane.								cellular_component											owl:Class	
GO:0102215	biolink:NamedThing	thiocyanate methyltransferase activity	Catalysis of the reaction: thiocyanate + S-adenosyl-L-methionine  <=> methyl thiocyanate + S-adenosyl-L-homocysteine.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-12189|RHEA:28014									molecular_function											owl:Class	
GO:0033607	biolink:NamedThing	SOD1-Bcl-2 complex	A heterodimeric protein complex formed of superoxide dismutase 1 and Bcl-2. Complex formation is thought to link superoxide dismutase to an apoptotic pathway.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0071419	biolink:NamedThing	cellular response to amphetamine	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amphetamine stimulus. Amphetamines consist of a group of compounds related to alpha-methylphenethylamine.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-12-14T04:09:02Z					biological_process											owl:Class	
GO:0071418	biolink:NamedThing	cellular response to amine stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amine stimulus. An amine is a compound formally derived from ammonia by replacing one, two or three hydrogen atoms by hydrocarbyl groups.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-12-14T04:08:17Z					biological_process											owl:Class	
GO:0015951	biolink:NamedThing	purine ribonucleotide interconversion	The chemical reactions and pathways by which a purine ribonucleotide is synthesized from another purine ribonucleotide.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0015544	biolink:NamedThing	phenyl propionate uniporter activity	Enables the transfer of phenyl propionate from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	phenyl propionate permease activity													molecular_function											owl:Class	
GO:0015292	biolink:NamedThing	uniporter activity	Catalysis of the transport of a single molecular species across a membrane; transport is independent of the movement of any other molecular species.	tmpzr1t_l9r_go_relaxed.owl	facilitated diffusion carrier|uniport|single-species transporter activity													molecular_function											owl:Class	
GO:0039622	biolink:NamedThing	T=16 icosahedral viral capsid	The protein coat that surrounds the infective nucleic acid in some virus particles where the subunits (capsomeres) are arranged to form an icosahedron with T=16 symmetry. The T=16 capsid is composed of 12 pentameric and 150 hexameric capsomeres.	tmpzr1t_l9r_go_relaxed.owl					VZ:807			bf	2012-07-18T02:20:23Z					cellular_component											owl:Class	
GO:0102877	biolink:NamedThing	alpha-copaene synthase activity	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate <=> alpha-copaene + diphosphoric acid.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-8416|EC:4.2.3.133|RHEA:33991									molecular_function											owl:Class	
GO:0005528	biolink:NamedThing	FK506 binding	Binding to a 23-membered macrolide lactone FK506.	tmpzr1t_l9r_go_relaxed.owl	FK506-sensitive peptidyl-prolyl cis-trans isomerase													molecular_function											owl:Class	
GO:1903063	biolink:NamedThing	negative regulation of reverse cholesterol transport	Any process that stops, prevents or reduces the frequency, rate or extent of reverse cholesterol transport.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of reverse cholesterol transport|downregulation of reverse cholesterol transport|inhibition of reverse cholesterol transport|down regulation of reverse cholesterol transport							rl	2014-05-28T15:15:34Z					biological_process											owl:Class	
GO:0103048	biolink:NamedThing	tRNA m2A37 methyltransferase activity	Catalysis of the reaction: 2 S-adenosyl-L-methionine  + an adenine37 in tRNA <=> S-adenosyl-L-homocysteine  + L-methionine  + 5'-deoxyadenosine + a 2-methyladenine37 in tRNA.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN0-7007									molecular_function											owl:Class	
GO:0061715	biolink:NamedThing	miRNA 2'-O-methylation	The posttranscriptional addition of a methyl group to the 2' oxygen atom of a nucleotide residue in an miRNA molecule.	tmpzr1t_l9r_go_relaxed.owl								dph	2015-06-29T08:41:03Z					biological_process											owl:Class	
GO:0001510	biolink:NamedThing	RNA methylation	Posttranscriptional addition of a methyl group to either a nucleotide or 2'-O ribose in a polyribonucleotide. Usually uses S-adenosylmethionine as a cofactor.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0043163	biolink:NamedThing	cell envelope organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the cell envelope, everything external to, but not including, the cytoplasmic membrane of bacteria, encompassing the periplasmic space, cell wall, and outer membrane if present.	tmpzr1t_l9r_go_relaxed.owl	cell envelope organisation|cell envelope organization and biogenesis													biological_process											owl:Class	
GO:0097245	biolink:NamedThing	flavanol binding	Binding to a flavanol.	tmpzr1t_l9r_go_relaxed.owl	flavan-3-ol binding							pr	2012-02-17T03:52:10Z					molecular_function											owl:Class	
GO:0102422	biolink:NamedThing	curcumin-4'-O-beta-D-gentiotrioside 1,6-glucosyltransferase activity	Catalysis of the reaction: curcumin 4'-O-beta-D-gentiotrioside + UDP-alpha-D-glucose <=> curcumin 4'-O-beta-D-gentiotetraside + UDP + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-13814									molecular_function											owl:Class	
GO:0047807	biolink:NamedThing	cytokinin 7-beta-glucosyltransferase activity	Catalysis of the reaction: 6-alkylaminopurine + UDP-D-glucose = 6-alkylamino-7-beta-D-glucosylpurine + H+ + UDP. This reaction is an N-glucosylation event.	tmpzr1t_l9r_go_relaxed.owl	cytokinin 7-glucosyltransferase activity|UDP-glucose:zeatin 7-glucosyltransferase activity|cytokinin 7-b-glucosyltransferase activity|UDPglucose:zeatin 7-glucosyltransferase activity|uridine diphosphoglucose-zeatin 7-glucosyltransferase activity|UDP-glucose-zeatin 7-glucosyltransferase activity				EC:2.4.1.118|KEGG_REACTION:R04071|RHEA:23272|MetaCyc:CYTOKININ-7-BETA-GLUCOSYLTRANSFERASE-RXN									molecular_function											owl:Class	
GO:0004335	biolink:NamedThing	galactokinase activity	Catalysis of the reaction: D-galactose + ATP = alpha-D-galactose 1-phosphate + ADP + 2 H(+).	tmpzr1t_l9r_go_relaxed.owl	ATP:D-galactose-1-phosphotransferase activity|ATP:D-galactose 1-phosphotransferase activity|galactokinase (phosphorylating)				EC:2.7.1.6|MetaCyc:GALACTOKIN-RXN|Reactome:R-HSA-5610026|RHEA:13553|KEGG_REACTION:R01092|Reactome:R-HSA-70355									molecular_function											owl:Class	
GO:0033175	biolink:NamedThing	chloroplast proton-transporting ATP synthase complex, coupling factor CF(o)	All non-F1 subunits of the chloroplast hydrogen-transporting ATP synthase, including integral and peripheral chloroplast thylakoid membrane proteins.	tmpzr1t_l9r_go_relaxed.owl	chloroplast proton-transporting F-type ATPase complex, coupling factor CF(o)|chloroplast proton-transporting ATP synthase complex, coupling factor CF(0)													cellular_component											owl:Class	
GO:0070630	biolink:NamedThing	(1->4)-alpha-glucan biosynthetic process	The chemical reactions and pathways resulting in the formation of (1->4)-alpha-glucans, compounds composed of glucose residues linked by (1->4)-alpha-D-glucosidic bonds.	tmpzr1t_l9r_go_relaxed.owl	alpha-1,4 glucan biosynthetic process|1,4-alpha-glucan biosynthetic process|1,4-alpha-glucan formation|alpha-1,4 glucan biosynthesis|1,4-alpha-glucan anabolism|alpha-1,4 glucan formation|alpha-1,4 glucan anabolism|(1->4)-alpha-D-glucan synthesis|1,4-alpha-glucan synthesis|(1->4)-alpha-D-glucan formation|1,4-alpha-glucan biosynthesis|(1->4)-alpha-D-glucan anabolism|(1->4)-alpha-D-glucan biosynthesis|alpha-1,4 glucan synthesis							mah	2009-05-01T04:46:34Z					biological_process											owl:Class	
GO:0060687	biolink:NamedThing	regulation of branching involved in prostate gland morphogenesis	Any process that modulates the rate, frequency, or extent of prostate gland branching, the process in which the branching structure of the prostate gland is generated and organized. A branch is a division or offshoot from a main stem.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-06-05T12:37:14Z					biological_process											owl:Class	
GO:0039675	biolink:NamedThing	exit of virus from host cell nucleus through nuclear pore	The directed movement of the viral genome or a viral particle out of the host cell nucleus through the nuclear pore.	tmpzr1t_l9r_go_relaxed.owl	exit of virus from host cell nucleus through nuclear pore complex|nuclear pore exit of virus|viral enome export through nuclear pore				VZ:1953			bf	2013-09-25T14:10:03Z					biological_process											owl:Class	
GO:0006747	biolink:NamedThing	FAD biosynthetic process	The chemical reactions and pathways resulting in the formation of FAD, the oxidized form of flavin-adenine dinucleotide.	tmpzr1t_l9r_go_relaxed.owl	FAD biosynthesis|oxidized flavin-adenine dinucleotide biosynthetic process|oxidized flavin adenine dinucleotide biosynthesis|oxidized flavin-adenine dinucleotide biosynthesis|oxidized flavin adenine dinucleotide biosynthetic process|FAD anabolism|FAD synthesis|FAD formation													biological_process											owl:Class	
GO:0044518	biolink:NamedThing	positive regulation of vasoactive intestinal polypeptide receptor activity in other organism	A process that activates or increases the frequency, rate or extent of the activity of a vasoactive intestinal polypeptide receptor in a second organism.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of VIP receptor activity in other organism							jl	2012-02-26T11:50:34Z					biological_process											owl:Class	
GO:0044517	biolink:NamedThing	modulation of vasoactive intestinal polypeptide receptor activity in other organism	The process in which an organism effects a change in the activity of a vasoactive intestinal polypeptide receptor in a second organism.	tmpzr1t_l9r_go_relaxed.owl	modulation of VIP receptor activity in other organism|regulation of vasoactive intestinal polypeptide receptor activity in other organism							jl	2012-02-26T11:48:32Z					biological_process											owl:Class	
GO:0019706	biolink:NamedThing	protein-cysteine S-palmitoyltransferase activity	Catalysis of the transfer of a palmitoyl (systematic name, hexadecanoyl) group to a sulfur atom on the cysteine of a protein molecule, in the reaction hexadecanoyl-CoA + L-cysteinyl-[protein] = CoA + S-hexadecanoyl-L-cysteinyl-[protein].	tmpzr1t_l9r_go_relaxed.owl	protein-cysteine S-palmitoleyltransferase activity				RHEA:36683|Reactome:R-HSA-9647982|Reactome:R-HSA-9021072|EC:2.3.1.225|Reactome:R-HSA-5682084									molecular_function											owl:Class	
GO:1904719	biolink:NamedThing	positive regulation of AMPA glutamate receptor clustering	Any process that activates or increases the frequency, rate or extent of AMPA glutamate receptor clustering.	tmpzr1t_l9r_go_relaxed.owl	activation of AMPA glutamate receptor clustering|up-regulation of AMPA glutamate receptor clustering|upregulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor clustering|activation of AMPA receptor clustering|up regulation of AMPA glutamate receptor clustering|positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor clustering|up-regulation of AMPA receptor clustering|up regulation of AMPA receptor clustering|activation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor clustering|positive regulation of AMPA receptor clustering|up regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor clustering|upregulation of AMPA glutamate receptor clustering|upregulation of AMPA receptor clustering|up-regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor clustering							hjd	2015-10-07T19:32:34Z					biological_process											owl:Class	
GO:0015328	biolink:NamedThing	cystine secondary active transmembrane transporter activity	Enables the transfer of cystine from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters.	tmpzr1t_l9r_go_relaxed.owl	lysosomal cystine transporter|cystinosin|cystine porter activity													molecular_function											owl:Class	
GO:0070219	biolink:NamedThing	cellular sulfide ion homeostasis	Any process involved in the maintenance of an internal steady state of sulfide ions at the level of a cell.	tmpzr1t_l9r_go_relaxed.owl	cellular sulphide ion homeostasis|cellular sulphide homeostasis|cellular sulfide homeostasis													biological_process											owl:Class	
GO:0050397	biolink:NamedThing	Watasenia-luciferin 2-monooxygenase activity	Catalysis of the reaction: Watasenia luciferin + O2 = oxidized Watasenia luciferin + CO2 + light.	tmpzr1t_l9r_go_relaxed.owl	Watasenia-luciferin:oxygen 2-oxidoreductase (decarboxylating)|Watasenia-type luciferase activity|luciferase activity				MetaCyc:WATASEMIA-LUCIFERIN-2-MONOOXYGENASE-RXN|RHEA:18057|EC:1.13.12.8									molecular_function											owl:Class	
GO:0035573	biolink:NamedThing	N-terminal peptidyl-serine trimethylation	The trimethylation of the N-terminal serine of proteins to form the derivative N,N,N-trimethylserine.	tmpzr1t_l9r_go_relaxed.owl								bf	2010-08-06T02:00:42Z					biological_process											owl:Class	
GO:2000971	biolink:NamedThing	negative regulation of detection of glucose	Any process that stops, prevents or reduces the frequency, rate or extent of detection of glucose.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of glucose detection|negative regulation of glucose perception|negative regulation of glucose sensing							vk	2011-08-02T10:18:54Z					biological_process											owl:Class	
GO:1990523	biolink:NamedThing	bone regeneration	The regrowth of bone following its loss or destruction.	tmpzr1t_l9r_go_relaxed.owl								sl	2014-10-30T15:47:39Z					biological_process											owl:Class	
GO:2000549	biolink:NamedThing	positive regulation of dendritic cell dendrite assembly	Any process that activates or increases the frequency, rate or extent of dendritic cell dendrite assembly.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of dendritic extension							ebc	2011-04-03T07:22:06Z					biological_process											owl:Class	
GO:0106138	biolink:NamedThing	Sec61 translocon complex binding	Binding to a Sec61 translocon complex.	tmpzr1t_l9r_go_relaxed.owl								hjd	2018-08-15T14:50:29Z					molecular_function											owl:Class	
GO:0072743	biolink:NamedThing	cellular response to erythromycin	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an erythromycin stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2012-08-31T12:24:52Z					biological_process											owl:Class	
GO:0007445	biolink:NamedThing	determination of imaginal disc primordium	Allocation of embryonic cells to the imaginal disc founder populations, groups of cells that are committed to contribute to the formation of an imaginal disc compartment.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0016248	biolink:NamedThing	channel inhibitor activity	Binds to and stops, prevents, or reduces the activity of a channel.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0008718	biolink:NamedThing	D-amino-acid dehydrogenase activity	Catalysis of the reaction: a D-amino acid + H2O + acceptor = a 2-oxo acid + NH3 + reduced acceptor.	tmpzr1t_l9r_go_relaxed.owl	D-amino-acid:(acceptor) oxidoreductase (deaminating)|D-amino-acid:acceptor oxidoreductase (deaminating)				RHEA:18125|MetaCyc:DAADEHYDROG-RXN									molecular_function											owl:Class	
GO:0002478	biolink:NamedThing	antigen processing and presentation of exogenous peptide antigen	The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC protein complex. The peptide is typically a fragment of a larger exogenous protein which has been degraded within the cell.	tmpzr1t_l9r_go_relaxed.owl	exogenous peptide antigen processing and presentation													biological_process											owl:Class	
GO:0106336	biolink:NamedThing	yolk syncytial layer development	The progression of the yolk syncytial layer over time, from its initial formation to the mature structure. The yolk syncytial layer is the peripheral layer of the yolk cell including nuclei and non-yolky cytoplasm.	tmpzr1t_l9r_go_relaxed.owl	YSL development					The "yolk syncytial layer" structure can be found in Teleostei, Myxini, Chondrichthyes, Lepisosteiformes and Cephalopoda according.		hjd	2020-11-05T17:56:43Z					biological_process											owl:Class	
GO:0047247	biolink:NamedThing	luteolin-7-O-diglucuronide 4'-O-glucuronosyltransferase activity	Catalysis of the reaction: luteolin 7-O-[(beta-D-glucosiduronate)-(1->2)-(beta-D-glucosiduronate)] + UDP-alpha-D-glucuronate = H(+) + luteolin 7-O-[(beta-D-glucosiduronate)-(1->2)-(beta-D-glucosiduronate)] 4'-O-beta-D-glucosiduronate + UDP.	tmpzr1t_l9r_go_relaxed.owl	UDP-glucuronate:luteolin-7-O-beta-D-diglucuronide 4'-O-glucuronosyltransferase activity|UDPglucuronate:luteolin-7-O-beta-D-diglucuronide 4'-O-glucuronosyltransferase activity|uridine diphosphoglucuronate-luteolin 7-O-diglucuronide glucuronosyltransferase activity|UDPglucuronate:luteolin 7-O-diglucuronide-4'-O-glucuronosyl-transferase activity|UDP-glucuronate:luteolin 7-O-diglucuronide-glucuronosyltransferase activity|LDT				KEGG_REACTION:R06828|EC:2.4.1.191|RHEA:22116|MetaCyc:2.4.1.191-RXN									molecular_function											owl:Class	
GO:0047745	biolink:NamedThing	chlorogenate hydrolase activity	Catalysis of the reaction: chlorogenate + H(2)O = (-)-quinate + cis-caffeate + H(+).	tmpzr1t_l9r_go_relaxed.owl	chlorogenase activity|chlorogenic acid esterase activity				MetaCyc:CHLOROGENATE-HYDROLASE-RXN|KEGG_REACTION:R02997|EC:3.1.1.42|RHEA:20689									molecular_function											owl:Class	
GO:0022613	biolink:NamedThing	ribonucleoprotein complex biogenesis	A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a complex containing RNA and proteins. Includes the biosynthesis of the constituent RNA and protein molecules, and those macromolecular modifications that are involved in synthesis or assembly of the ribonucleoprotein complex.	tmpzr1t_l9r_go_relaxed.owl	RNA-protein complex biogenesis|ribonucleoprotein complex biogenesis and assembly													biological_process											owl:Class	
GO:0140496	biolink:NamedThing	gamma-tubulin complex binding	Binding to a gamma-tubulin complex.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/19788						pg	2020-07-17T08:14:32Z					molecular_function											owl:Class	
GO:0007541	biolink:NamedThing	sex determination, primary response to X:A ratio	The developmental process in which an organism interprets its X to autosomal chromosomal complement.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0030795	biolink:NamedThing	methyl jasmonate methylesterase activity	Catalysis of the reaction: S-adenosyl-L-methionine + a jasmonate = S-adenosyl-L-homocysteine + a methyljasmonate.	tmpzr1t_l9r_go_relaxed.owl	S-adenosyl-L-methionine:jasmonate O-methyltransferase activity|S-adenosyl-L-methionine:jasmonic acid carboxyl methyltransferase activity|jasmonic acid carboxyl methyltransferase activity				RHEA:13349|EC:2.1.1.141|MetaCyc:RXN-10768							GO:0102078|GO:0045546		molecular_function											owl:Class	
GO:1903511	biolink:NamedThing	orotic acid metabolic process	The chemical reactions and pathways involving orotic acid.	tmpzr1t_l9r_go_relaxed.owl	orotic acid metabolism							dph	2014-10-01T21:58:06Z					biological_process											owl:Class	
GO:0098551	biolink:NamedThing	lumenal side of late endosome membrane	The side (leaflet) of the late endosome membrane that faces the lumen.	tmpzr1t_l9r_go_relaxed.owl	internal side of late endosome membrane|internal leaflet of late endosome membrane													cellular_component											owl:Class	
GO:0046900	biolink:NamedThing	tetrahydrofolylpolyglutamate metabolic process	The chemical reactions and pathways involving tetrahydrofolylpolyglutamate, a folate derivative comprising tetrahydrofolate attached to a chain of glutamate residues.	tmpzr1t_l9r_go_relaxed.owl	tetrahydrofolyl-[Glu](n) metabolic process|tetrahydrofolyl-[Glu](n) metabolism|tetrahydrofolylpolyglutamate metabolism													biological_process											owl:Class	
GO:0018101	biolink:NamedThing	protein citrullination	The hydrolysis of peptidyl-arginine to form peptidyl-citrulline.	tmpzr1t_l9r_go_relaxed.owl	peptidyl-citrulline synthesis from peptidyl-arginine|peptidyl-citrulline biosynthetic process from peptidyl-arginine|peptidyl-citrulline anabolism from peptidyl-arginine|deimination|peptidyl-citrulline formation from peptidyl-arginine				RESID:AA0214	Citrullination is distinct from the formation of the free amino acid citrulline (e.g. as part of the urea cycle).								biological_process											owl:Class	
GO:0000834	biolink:NamedThing	inositol heptakisphosphate 6-kinase activity	Catalysis of the reaction: ATP + 5-diphospho-1D-myo-inositol (1,2,3,4,6)pentakisphosphate = 5,6-bisdiphosphoinositol-1D-myoinositol (1,2,3,4)tetrakisphosphate.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0062122	biolink:NamedThing	histone methyltransferase activity (H3-K37 specific)	Catalysis of the reaction: S-adenosyl-L-methionine + histone H3 L-lysine (position 37) = S-adenosyl-L-homocysteine + histone H3 N6-methyl-L-lysine (position 37). This reaction is the addition of a methyl group onto lysine at position 37 of the histone H3 protein.	tmpzr1t_l9r_go_relaxed.owl	histone lysine N-methyltransferase activity (H3-K37 specific)							dph	2019-04-01T13:30:11Z					molecular_function											owl:Class	
GO:0044104	biolink:NamedThing	2,5-dioxovalerate dehydrogenase (NAD+) activity	Catalysis of the reaction: 2,5-dioxopentanoate + NAD+ + H2O = 2-oxoglutarate + NADH + H+.	tmpzr1t_l9r_go_relaxed.owl	2,5-dioxopentanoate:NAD+ 5-oxidoreductase activity|2,5-dioxopentanoate dehydrogenase (NAD+) activity							jl	2009-07-09T04:15:14Z					molecular_function											owl:Class	
GO:0060710	biolink:NamedThing	chorio-allantoic fusion	The cell-cell adhesion process in which the cells of the chorion fuse to the cells of the allantois.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-06-09T03:24:27Z					biological_process											owl:Class	
GO:1990037	biolink:NamedThing	Lewy body core	The center portion of a Lewy body. In Parkinson's disease, it contains a matted meshwork of filaments.	tmpzr1t_l9r_go_relaxed.owl					NIF_Subcellular:sao6587439252			pr	2013-02-08T12:56:59Z					cellular_component											owl:Class	
GO:0030733	biolink:NamedThing	fatty acid O-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + a fatty acid = S-adenosyl-L-homocysteine + a fatty acid methyl ester.	tmpzr1t_l9r_go_relaxed.owl	S-adenosyl-L-methionine:fatty-acid O-methyltransferase activity|fatty acid methyltransferase activity|fatty-acid O-methyltransferase activity				MetaCyc:FATTY-ACID-O-METHYLTRANSFERASE-RXN|RHEA:23012|EC:2.1.1.15									molecular_function											owl:Class	
GO:0102969	biolink:NamedThing	10-oxogeraniol oxidoreductase activity	Catalysis of the reaction: (6E)-8-oxogeraniol + NADP <=> (6E)-8-oxogeranial + NADPH + H+.	tmpzr1t_l9r_go_relaxed.owl					RHEA:32615|MetaCyc:RXN-9370									molecular_function											owl:Class	
GO:1904185	biolink:NamedThing	equatorial microtubule organizing center assembly	The aggregation, arrangement and bonding together of a set of components to form an equatorial microtubule organizing center.	tmpzr1t_l9r_go_relaxed.owl	EMTOC formation|equatorial microtubule organising centre assembly|equatorial microtubule organizing center formation|equatorial microtubule organising centre formation|EMTOC assembly							mah	2015-05-05T14:24:30Z					biological_process											owl:Class	
GO:0047801	biolink:NamedThing	L-cysteine:2-oxoglutarate aminotransferase activity	Catalysis of the reaction: L-cysteine + 2-oxoglutarate = mercaptopyruvate + L-glutamate.	tmpzr1t_l9r_go_relaxed.owl	L-cysteine aminotransferase activity|cysteine transaminase activity|cysteine aminotransferase activity|CGT				EC:2.6.1.3|Reactome:R-HSA-9012597|RHEA:17441|MetaCyc:CYSTEINE-AMINOTRANSFERASE-RXN									molecular_function											owl:Class	
GO:0034546	biolink:NamedThing	2,4-dichloroaniline reductive dehalogenase activity	Catalysis of the reaction: 2,4-dichloroaniline + 2 H+ + 2 e- = 4-chloroaniline + HCl.	tmpzr1t_l9r_go_relaxed.owl					EC:1.97.1.-|UM-BBD_reactionID:r0819									molecular_function											owl:Class	
GO:0051013	biolink:NamedThing	microtubule severing	The process in which a microtubule is broken down into smaller segments. Severing enzymes remove dimers from the middle of the filament to create new ends, unlike depolymerizing kinesins that use ATP to uncap microtubules at their ends.	tmpzr1t_l9r_go_relaxed.owl	microtubule severing activity													biological_process											owl:Class	
GO:0035486	biolink:NamedThing	cytosine/cytosine mispair binding	Binding to a double-stranded DNA region containing a C/C mispair.	tmpzr1t_l9r_go_relaxed.owl	C/C mispair binding							bf	2010-04-23T10:56:10Z					molecular_function											owl:Class	
GO:0030778	biolink:NamedThing	columbamine O-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + columbamine = S-adenosyl-L-homocysteine + H(+) + palmatine.	tmpzr1t_l9r_go_relaxed.owl	S-adenosyl-L-methionine:columbamine O-methyltransferase activity				MetaCyc:2.1.1.118-RXN|RHEA:15373|KEGG_REACTION:R03721|EC:2.1.1.118									molecular_function											owl:Class	
GO:0050363	biolink:NamedThing	tryptophan dehydrogenase activity	Catalysis of the reaction: L-tryptophan + NAD(P)+ = (indol-3-yl)pyruvate + NH3 + NAD(P)H + H+.	tmpzr1t_l9r_go_relaxed.owl	TrpDH activity|L-tryptophan dehydrogenase activity|L-Trp-dehydrogenase activity|TDH|L-tryptophan:NAD(P)+ oxidoreductase (deaminating)|NAD(P)+-L-tryptophan dehydrogenase activity				MetaCyc:TRYPTOPHAN-DEHYDROGENASE-RXN|EC:1.4.1.19									molecular_function											owl:Class	
GO:0051754	biolink:NamedThing	meiotic sister chromatid cohesion, centromeric	The cell cycle process in which centromeres of sister chromatids are joined during meiosis.	tmpzr1t_l9r_go_relaxed.owl	centromeric meiotic sister chromatin cohesion|meiotic sister chromatid cohesion at centromere|sister chromatid cohesion at centromere at meiosis I													biological_process											owl:Class	
GO:0015989	biolink:NamedThing	light-driven proton transport	The transport of protons against an electrochemical gradient, using energy from light.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1902064	biolink:NamedThing	regulation of transcription from RNA polymerase II promoter involved in spermatogenesis	Any regulation of transcription from RNA polymerase II promoter that is involved in spermatogenesis.	tmpzr1t_l9r_go_relaxed.owl	regulation of global transcription from Pol II promoter involved in generation of spermatozoa|regulation of transcription from RNA polymerase II promoter, global involved in generation of spermatozoa|regulation of transcription from RNA polymerase II promoter, global involved in spermatogenesis|regulation of transcription from RNA polymerase II promoter involved in generation of spermatozoa|regulation of gene-specific transcription from RNA polymerase II promoter involved in spermatogenesis|regulation of gene-specific transcription from RNA polymerase II promoter involved in generation of spermatozoa|global transcription regulation from Pol II promoter involved in generation of spermatozoa|regulation of transcription from Pol II promoter involved in generation of spermatozoa|regulation of global transcription from Pol II promoter involved in spermatogenesis|regulation of transcription from Pol II promoter involved in spermatogenesis|global transcription regulation from Pol II promoter involved in spermatogenesis							kmv	2013-04-16T20:27:18Z					biological_process											owl:Class	
GO:0015666	biolink:NamedThing	restriction endodeoxyribonuclease activity	Catalysis of endonucleolytic cleavage of DNA in a site-specific manner, resulting in double-strand breaks.	tmpzr1t_l9r_go_relaxed.owl	restriction endonuclease activity|restriction enzyme activity													molecular_function											owl:Class	
GO:0080115	biolink:NamedThing	myosin XI tail binding	Binding to the tail region of a myosin XI heavy chain.	tmpzr1t_l9r_go_relaxed.owl								dhl	2009-04-27T03:31:45Z					molecular_function											owl:Class	
GO:1900725	biolink:NamedThing	osmoregulated periplasmic glucan metabolic process	The chemical reactions and pathways involving osmoregulated periplasmic glucan.	tmpzr1t_l9r_go_relaxed.owl	osmoregulated periplasmic glucan metabolism							jl	2012-05-24T03:18:32Z					biological_process											owl:Class	
GO:1903816	biolink:NamedThing	positive regulation of collecting lymphatic vessel constriction	Any process that activates or increases the frequency, rate or extent of collecting lymphatic vessel constriction.	tmpzr1t_l9r_go_relaxed.owl	up regulation of lymphatic vessel myogenic constriction|activation of collecting lymphatic vessel constriction|up-regulation of collecting lymphatic vessel constriction|positive regulation of lymphatic vessel myogenic constriction|upregulation of collecting lymphatic vessel constriction|activation of lymphatic vessel myogenic constriction|upregulation of lymphatic vessel myogenic constriction|up regulation of collecting lymphatic vessel constriction|up-regulation of lymphatic vessel myogenic constriction							sl	2015-01-16T17:02:08Z					biological_process											owl:Class	
GO:0050534	biolink:NamedThing	3-deoxyoctulosonase activity	Catalysis of the reaction: 3-deoxyoctulosonyl-lipopolysaccharide + H2O = 3-deoxyoctulosonic acid + lipopolysaccharide.	tmpzr1t_l9r_go_relaxed.owl	3-deoxyoctulosonyl-lipopolysaccharide hydrolase activity|alpha-Kdo-ase activity				EC:3.2.1.144|MetaCyc:3.2.1.144-RXN									molecular_function											owl:Class	
GO:0032130	biolink:NamedThing	medial membrane band assembly	The assembly of a sterol-rich region of the plasma membrane at the cell surface overlying the contractile ring.	tmpzr1t_l9r_go_relaxed.owl	medial membrane band formation													biological_process											owl:Class	
GO:0042893	biolink:NamedThing	polymyxin transport	The directed movement of polymyxin, any of a group of related antibiotics produced by Bacillus polymyxa and active against most Gram-negative bacteria, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0098826	biolink:NamedThing	endoplasmic reticulum tubular network membrane	The membrane of the endoplasmic reticulum tubular network.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0001651	biolink:NamedThing	dense fibrillar component	A structure found in the nucleolus, which contains newly synthesized preribosomal RNA (pre-rRNA) and a collection of proteins.	tmpzr1t_l9r_go_relaxed.owl	pars fibrosa				NIF_Subcellular:sao1841764412									cellular_component											owl:Class	
GO:0042915	biolink:NamedThing	group A colicin transport	The directed movement of group A colicins (colicins E1, E2, E3, A, K, and N) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0043579	biolink:NamedThing	elaioplast organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an elaioplast, a leucoplast in which oil is stored.	tmpzr1t_l9r_go_relaxed.owl	elaioplast organization and biogenesis|elaioplast organisation													biological_process											owl:Class	
GO:0009659	biolink:NamedThing	leucoplast organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a leucoplast. A leucoplast is a colorless plastid involved in the synthesis of monoterpenes.	tmpzr1t_l9r_go_relaxed.owl	leucoplast organisation|leucoplast organization and biogenesis													biological_process											owl:Class	
GO:0046544	biolink:NamedThing	development of secondary male sexual characteristics	The process whose specific outcome is the progression of the secondary male sexual characteristics over time, from their formation to the mature structures. In male humans, these include growth of axillary, chest, and pubic hair, voice changes, and testicular/penile enlargement. Development occurs in response to sex hormone secretion.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0007633	biolink:NamedThing	pattern orientation	The actions or reactions of an individual in response to the orientation of a visual pattern. This is exemplified by some classes of insects which are able to detect and learn the orientation of a set of stripes and subsequently behaviorally discriminate between horizontal, vertical or 45 degree stripes.	tmpzr1t_l9r_go_relaxed.owl	behavioral response to pattern orientation|behavioural response to pattern orientation													biological_process											owl:Class	
GO:0047559	biolink:NamedThing	3-dehydro-L-gulonate 2-dehydrogenase activity	Catalysis of the reaction: 3-dehydro-L-gulonate + NAD(P)+ = (4R,5S)-4,5,6-trihydroxy-2,3-dioxohexanoate + NAD(P)H + H+.	tmpzr1t_l9r_go_relaxed.owl	3-keto-L-gulonate dehydrogenase activity|2,3-diketo-L-gulonate reductase activity|3-ketogulonate dehydrogenase activity|3-dehydro-L-gulonate:NAD(P)+ 2-oxidoreductase activity				MetaCyc:3-DEHYDRO-L-GULONATE-2-DEHYDROGENASE-RXN|EC:1.1.1.130									molecular_function											owl:Class	
GO:0001154	biolink:NamedThing	TFIIIB-class transcription factor complex binding	Binding to a general RNA polymerase III transcription factor belonging to the TFIIB complex, one of the factors involved in formation of the preinitiation complex (PIC) by RNA polymerase III.	tmpzr1t_l9r_go_relaxed.owl	TFIIIB-class transcription factor binding							krc	2011-01-27T04:53:50Z					molecular_function											owl:Class	
GO:1904285	biolink:NamedThing	regulation of protein-pyridoxal-5-phosphate linkage	Any process that modulates the frequency, rate or extent of protein-pyridoxal-5-phosphate linkage.	tmpzr1t_l9r_go_relaxed.owl								mcc	2015-06-05T17:21:14Z					biological_process											owl:Class	
GO:0019746	biolink:NamedThing	hopanoid biosynthetic process	The chemical reactions and pathways resulting in the formation of hopanoids, pentacyclic sterol-like compounds based on the hopane nucleus.	tmpzr1t_l9r_go_relaxed.owl	hopanoid biosynthesis|hopanoid formation|hopanoid synthesis|hopanoid anabolism													biological_process											owl:Class	
GO:0004419	biolink:NamedThing	hydroxymethylglutaryl-CoA lyase activity	Catalysis of the reaction: (S)-3-hydroxy-3-methylglutaryl-CoA = acetoacetate + acetyl-CoA.	tmpzr1t_l9r_go_relaxed.owl	3-hydroxy-3-methylglutaryl coenzyme A lyase activity|3-hydroxy-3-methylglutarate-CoA lyase activity|(S)-3-hydroxy-3-methylglutaryl-CoA acetoacetate-lyase activity|(S)-3-hydroxy-3-methylglutaryl-CoA acetoacetate-lyase (acetyl-CoA-forming)|3-hydroxy-3-methylglutaryl-CoA lyase activity|3-hydroxy-3-methylglutaryl CoA cleaving enzyme|hydroxymethylglutaryl coenzyme A-cleaving enzyme|HMG-CoA lyase activity|hydroxymethylglutaryl coenzyme A lyase activity				MetaCyc:HYDROXYMETHYLGLUTARYL-COA-LYASE-RXN|EC:4.1.3.4|RHEA:24404|Reactome:R-HSA-6788597|Reactome:R-HSA-74180|KEGG_REACTION:R01360									molecular_function											owl:Class	
GO:0051982	biolink:NamedThing	copper-nicotianamine transmembrane transporter activity	Enables the transfer of the copper chelate copper-nicotianamine (Cu-NA) from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	Cu-NA chelate transporter activity													molecular_function											owl:Class	
GO:0018341	biolink:NamedThing	peptidyl-lysine modification to peptidyl-N6-pyruvic acid 2-iminyl-L-lysine	The modification of peptidyl-lysine to form peptidyl-N6-pyruvic acid 2-iminyl-L-lysine.	tmpzr1t_l9r_go_relaxed.owl	peptidyl-N6-pyruvic acid 2-iminyl-L-lysine anabolism|peptidyl-N6-pyruvic acid 2-iminyl-L-lysine synthesis|peptidyl-N6-pyruvic acid 2-iminyl-L-lysine biosynthesis|peptidyl-N6-pyruvic acid 2-iminyl-L-lysine formation|peptidyl-N6-pyruvic acid 2-iminyl-L-lysine biosynthetic process													biological_process											owl:Class	
GO:0061623	biolink:NamedThing	glycolytic process from galactose	The chemical reactions and pathways resulting in the breakdown of galactose into pyruvate, with the concomitant production of a small amount of ATP.	tmpzr1t_l9r_go_relaxed.owl								dph	2014-04-28T08:13:38Z					biological_process											owl:Class	
GO:1900248	biolink:NamedThing	negative regulation of cytoplasmic translational elongation	Any process that stops, prevents or reduces the frequency, rate or extent of cytoplasmic translational elongation.	tmpzr1t_l9r_go_relaxed.owl	inhibition of cytoplasmic translational elongation|downregulation of cytoplasmic translational elongation|down-regulation of cytoplasmic translational elongation|down regulation of cytoplasmic translational elongation							vw	2012-04-03T05:07:14Z					biological_process											owl:Class	
GO:0007007	biolink:NamedThing	inner mitochondrial membrane organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the mitochondrial inner membrane.	tmpzr1t_l9r_go_relaxed.owl	inner mitochondrial membrane organization and biogenesis|inner mitochondrial membrane organisation|mitochondrial inner membrane organization					See also the cellular component term 'mitochondrial inner membrane ; GO:0005743'.								biological_process											owl:Class	
GO:0015624	biolink:NamedThing	ABC-type ferric-enterobactin transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + ferric-enterobactin(out) = ADP + phosphate + ferric-enterobactin(in).	tmpzr1t_l9r_go_relaxed.owl	ATP-dependent ferric-enterobactin transmembrane transporter activity|ferric-enterobactin ABC transporter|ferric-enterobactin porter activity|ATPase-coupled ferric-enterobactin transmembrane transporter activity|ferric-enterobactin-transporting ATPase activity				MetaCyc:ABC-10-RXN|RHEA:58492|EC:7.2.2.17									molecular_function											owl:Class	
GO:0033208	biolink:NamedThing	UDP-N-acetylgalactosamine:N-acetylneuraminyl-alpha-2,3-galactosyl-beta-R 1,4-N-acetylgalactosaminyltransferase activity	Catalysis of the reaction: UDP-N-acetylgalactosamine + N-acetylneuraminyl-alpha-2,3-galactosyl-beta-oligosaccharide = UDP + N-acetylgalactosaminyl-N-acetylneuraminyl-alpha-2,3-galactosyl-beta-oligosaccharide.	tmpzr1t_l9r_go_relaxed.owl	UDP-GalNAc:Neu5Ac-alpha-2-Gal-beta-1-R beta-1,4-N-acetylgalactosaminyltransferase activity|Sda beta 1,4GalNAc transferase													molecular_function											owl:Class	
GO:0033207	biolink:NamedThing	beta-1,4-N-acetylgalactosaminyltransferase activity	Catalysis of the transfer of an N-acetylgalactosaminyl residue from UDP-N-acetyl-galactosamine to an acceptor molecule, forming a beta-1,4 linkage.	tmpzr1t_l9r_go_relaxed.owl	beta-1,4-GalNAc transferase activity													molecular_function											owl:Class	
GO:0002117	biolink:NamedThing	amphibian larval development	The process whose specific outcome is the progression of the amphibian larva over time, from its formation to the mature structure. Amphibian larvae, sometimes called pollywogs or tadpoles, hatch from eggs and begin to grow limbs and other adult physical features at various times, depending on the species, before they metamorphose into the adult form.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0040035	biolink:NamedThing	hermaphrodite genitalia development	The process whose specific outcome is the progression of the hermaphrodite genitalia over time, from formation to the mature structures.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0031274	biolink:NamedThing	positive regulation of pseudopodium assembly	Any process that activates or increases the frequency, rate or extent of the assembly of pseudopodia.	tmpzr1t_l9r_go_relaxed.owl	stimulation of pseudopodium formation|up-regulation of pseudopodium formation|activation of pseudopodium formation|up regulation of pseudopodium formation|positive regulation of pseudopodium formation|upregulation of pseudopodium formation													biological_process											owl:Class	
GO:0010486	biolink:NamedThing	manganese:proton antiporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Mn2+(in) + H+(out) = Mn2+(out) + H+(in).	tmpzr1t_l9r_go_relaxed.owl	manganese:hydrogen antiporter activity													molecular_function											owl:Class	
GO:0060594	biolink:NamedThing	mammary gland specification	The regionalization process in which the mammary line is specified. The mammary line is a ridge of epidermal cells that will form the mammary placodes.	tmpzr1t_l9r_go_relaxed.owl	mammary line specification							dph	2009-05-13T10:09:10Z					biological_process											owl:Class	
GO:0019092	biolink:NamedThing	mitochondrial srRNA export from mitochondrion	The process in which a srRNA, small subunit ribosomal ribonucleic acid, is transported from the mitochondrial matrix into the cytosol.	tmpzr1t_l9r_go_relaxed.owl	mitochondrial srRNA export from mitochondria|export of mitochondrial srRNA|mitochondrial srRNA transport from mitochondrion|mitochondrial srRNA, mitochondrial export|mitochondrial srRNA export out of mitochondrion|mitochondrial srRNA export													biological_process											owl:Class	
GO:0043621	biolink:NamedThing	protein self-association	Binding to a domain within the same polypeptide.	tmpzr1t_l9r_go_relaxed.owl	protein self binding|protein self association|intramolecular protein binding													molecular_function											owl:Class	
GO:0052034	biolink:NamedThing	effector-mediated suppression of host pattern-triggered immunity	A process mediated by a molecule secreted by a symbiont that results in the suppression of the innate immune response of the host organism via recognition of a microbe-associated molecular pattern. The innate immune response is the host's first line of defense against infection. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	suppression of general elicitor induced host innate immunity|suppression of MAMP-induced host innate immunity|negative regulation by symbiont of microbe-associated molecular pattern-induced host innate immune response|negative regulation by symbiont of microbe-associated molecular pattern-induced host innate immunity|inhibition by symbiont of pathogen-associated molecular pattern-induced host innate immunity|negative regulation by organism of pathogen-associated molecular pattern-induced innate immune response of other organism involved in symbiotic interaction|downregulation by symbiont of pathogen-associated molecular pattern-induced host innate immunity|suppression by symbiont of microbe-associated molecular pattern-induced host innate immune response|suppression of PAMP induced host innate immunity|down regulation by symbiont of pathogen-associated molecular pattern-induced host innate immunity|down-regulation by symbiont of pathogen-associated molecular pattern-induced host innate immunity|suppression of MAMP induced host innate immunity|suppression of general elicitor-induced host innate immunity|suppression of PAMP-induced host innate immunity|suppression of pathogen-associated molecular pattern-induced host innate immunity	https://github.com/geneontology/go-ontology/issues/21161										GO:0052258		biological_process											owl:Class	
GO:0009061	biolink:NamedThing	anaerobic respiration	The enzymatic release of energy from inorganic and organic compounds (especially carbohydrates and fats) which uses compounds other than oxygen (e.g. nitrate, sulfate) as the terminal electron acceptor.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Cellular_respiration#Anaerobic_respiration|MetaCyc:ANARESP1-PWY|Wikipedia:Anaerobic_respiration									biological_process											owl:Class	
GO:0020020	biolink:NamedThing	food vacuole	Vacuole within a parasite used for digestion of the host cell cytoplasm. An example of this component is found in the Apicomplexa.	tmpzr1t_l9r_go_relaxed.owl	digestive vacuole											GO:0005772		cellular_component											owl:Class	
GO:0051788	biolink:NamedThing	response to misfolded protein	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a misfolded protein stimulus.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0047579	biolink:NamedThing	4-hydroxymandelate oxidase activity	Catalysis of the reaction: (S)-4-hydroxymandelate + H(+) + O(2) = 4-hydroxybenzaldehyde + CO(2) + H(2)O(2).	tmpzr1t_l9r_go_relaxed.owl	L-4-hydroxymandelate oxidase (decarboxylating)|(S)-2-hydroxy-2-(4-hydroxyphenyl)acetate:oxygen 1-oxidoreductase activity				MetaCyc:4-HYDROXYMANDELATE-OXIDASE-RXN|RHEA:15833|KEGG_REACTION:R02673|EC:1.1.3.19									molecular_function											owl:Class	
GO:0015974	biolink:NamedThing	guanosine pentaphosphate catabolic process	The chemical reactions and pathways resulting in the breakdown of guanine pentaphosphate (5'-pppGpp-3'), a derivative of guanine riboside with five phosphates.	tmpzr1t_l9r_go_relaxed.owl	guanosine pentaphosphate breakdown|guanosine pentaphosphate (5'-pppGpp-3') catabolism|guanosine pentaphosphate catabolism|guanosine pentaphosphate (5'-pppGpp-3') catabolic process|guanosine pentaphosphate degradation													biological_process											owl:Class	
GO:0017025	biolink:NamedThing	TBP-class protein binding	Binding to a member of the class of TATA-binding proteins (TBP), including any of the TBP-related factors (TRFs).	tmpzr1t_l9r_go_relaxed.owl	TATA-binding protein binding|TBP-related factor (TRF) protein binding|TBP binding													molecular_function											owl:Class	
GO:0061015	biolink:NamedThing	snRNA import into nucleus	The directed movement of snRNA, small nuclear ribonucleic acid into the nucleus.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-01-29T02:36:00Z					biological_process											owl:Class	
GO:0060333	biolink:NamedThing	interferon-gamma-mediated signaling pathway	A series of molecular signals initiated by the binding of interferon-gamma to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. Interferon gamma is the only member of the type II interferon found so far.	tmpzr1t_l9r_go_relaxed.owl	type II interferon-mediated signaling pathway|immune interferon signaling pathway|gamma-interferon-mediated signaling pathway|type II IFN-mediated signaling pathway|interferon-gamma-mediated signalling pathway													biological_process											owl:Class	
GO:0098029	biolink:NamedThing	icosahedral viral capsid, spike	A short structure attached to an icosahedral virion capsid, and used for attachment to the host cell.	tmpzr1t_l9r_go_relaxed.owl								bm	2012-07-19T14:37:11Z					cellular_component											owl:Class	
GO:0006670	biolink:NamedThing	sphingosine metabolic process	The chemical reactions and pathways involving sphingosine (sphing-4-enine), trans-D-erytho-2-amino-octadec-4-ene-1,3-diol, a long chain amino diol sphingoid base that occurs in most sphingolipids in animal tissues.	tmpzr1t_l9r_go_relaxed.owl	(4E)-sphing-4-enine metabolism|sphingosine metabolism|sphing-4-enine metabolism|(4E)-sphing-4-enine metabolic process|sphing-4-enine metabolic process													biological_process											owl:Class	
GO:0071920	biolink:NamedThing	cleavage body	A nuclear body that contains proteins involved in pre-mRNA 3'-end cleavage and polyadenylation, such as DDX1, CSTF2 and CPSFs, as well as the transcription factors TFIIE and TFIIF. Cleavage bodies are localized adjacent to Cajal bodies and are involved in mRNA3'-end processing.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-09-28T10:35:05Z					cellular_component											owl:Class	
GO:0015505	biolink:NamedThing	uracil:cation symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: uracil(out) + cation(out) = uracil(in) + cation(in).	tmpzr1t_l9r_go_relaxed.owl	uracil permease activity													molecular_function											owl:Class	
GO:0042008	biolink:NamedThing	interleukin-18 receptor activity	Combining with interleukin-18 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	IL-18R|IL-18 receptor activity													molecular_function											owl:Class	
GO:0010473	biolink:NamedThing	GDP-galactose:myoinositol-1-phosphate guanylyltransferase activity	Catalysis of the reaction: GDP-L-galactose + myo-inositol 1-phosphate = alpha-L-galactose-1-phosphate + GDP-myoinositol.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0033058	biolink:NamedThing	directional locomotion	Self-propelled movement of a cell or organism from one location to another along an axis.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0098820	biolink:NamedThing	trans-synaptic protein complex	A protein complex that spans the synaptic cleft and has parts in both the pre- and post-synaptic membranes.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0050815	biolink:NamedThing	phosphoserine residue binding	Binding to a phosphorylated serine residue within a protein.	tmpzr1t_l9r_go_relaxed.owl	phosphoserine binding													molecular_function											owl:Class	
GO:1904384	biolink:NamedThing	cellular response to sodium phosphate	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sodium phosphate stimulus.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-06-23T16:55:13Z					biological_process											owl:Class	
GO:0018569	biolink:NamedThing	hydroquinone 1,2-dioxygenase activity	Catalysis of the reaction: hydroquinone + O2 = cis,trans-4-hydroxymuconic semialdehyde.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0228|EC:1.13.11.-									molecular_function											owl:Class	
GO:0005151	biolink:NamedThing	interleukin-1, type II receptor binding	Binding to a Type II interleukin-1 receptor.	tmpzr1t_l9r_go_relaxed.owl	interleukin-1, type II receptor ligand|IL-1 type II													molecular_function											owl:Class	
GO:0052925	biolink:NamedThing	dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase activity	Catalysis of the reaction: an alpha-D-man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-(alpha-D-Man-(1->6))-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-diphosphodolichol + dolichyl D-mannosyl phosphate = H(+) + alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-(alpha-D-Man-(1->3)-alpha-D-Man-(1->6))-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-diphosphodolichol + dolichyl phosphate.	tmpzr1t_l9r_go_relaxed.owl	dolichyl-P-Man:Man(5)GlcNAc(2)-PP-dolichyl mannosyltransferase activity|man(5)GlcNAc(2)-PP-Dol mannosyltransferase activity				MetaCyc:RXN-5466|RHEA:29527|EC:2.4.1.258|KEGG_REACTION:R06258									molecular_function											owl:Class	
GO:0001732	biolink:NamedThing	formation of cytoplasmic translation initiation complex	Joining of the large subunit, with release of IF2/eIF2 and IF3/eIF3. This leaves the functional ribosome at the AUG, with the methionyl/formyl-methionyl-tRNA positioned at the P site.	tmpzr1t_l9r_go_relaxed.owl	translation initiation complex assembly|cytoplasmic translation initiation complex assembly|formation of translation initiation complex													biological_process											owl:Class	
GO:0017176	biolink:NamedThing	phosphatidylinositol N-acetylglucosaminyltransferase activity	Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + phosphatidylinositol = UDP + N-acetyl-D-glucosaminylphosphatidylinositol.	tmpzr1t_l9r_go_relaxed.owl	uridine diphosphoacetylglucosamine alpha-1,6-acetyl-D-glucosaminyltransferase activity|UDP-N-acetyl-D-glucosamine:1-phosphatidyl-1D-myo-inositol 6-(N-acetyl-alpha-D-glucosaminyl)transferase activity|uridine diphosphoacetylglucosamine alpha1,6-acetyl-D-glucosaminyltransferase activity|UDP-N-acetyl-D-glucosamine:phosphatidylinositol N-acetyl-D-glucosaminyltransferase activity				RHEA:14789|EC:2.4.1.198|MetaCyc:2.4.1.198-RXN									molecular_function											owl:Class	
GO:0097375	biolink:NamedThing	spinal sensory neuron axon guidance	The process in which the migration of an axon growth cone of a spinal sensory neuron is directed to a specific target site in response to a combination of attractive and repulsive cues. A spinal sensory neuron is a sensory neuron that project to the spinal cord.	tmpzr1t_l9r_go_relaxed.owl								pr	2012-10-01T10:17:20Z					biological_process											owl:Class	
GO:1905903	biolink:NamedThing	negative regulation of mesoderm formation	Any process that stops, prevents or reduces the frequency, rate or extent of mesoderm formation.	tmpzr1t_l9r_go_relaxed.owl	inhibition of mesoderm formation|downregulation of mesoderm formation|down-regulation of mesoderm formation|down regulation of mesoderm formation							rph	2017-02-03T12:28:29Z					biological_process											owl:Class	
GO:1990028	biolink:NamedThing	intermediate voltage-gated calcium channel activity	Enables the transmembrane transfer of a calcium ion by an intermediate voltage-gated channel. An intermediate voltage-gated channel is a channel whose open state is dependent on intermediate voltage across the membrane in which it is embedded.	tmpzr1t_l9r_go_relaxed.owl	R-type calcium channel							pr	2013-02-06T20:55:41Z					molecular_function											owl:Class	
GO:0102165	biolink:NamedThing	(Z)-3-hexen-1-ol acetyltransferase activity	Catalysis of the reaction: acetyl-CoA + (Z)-hex-3-en-1-ol <=> (3Z)-hex-3-en-1-yl acetate + coenzyme A.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-11852|RHEA:28254|EC:2.3.1.195									molecular_function											owl:Class	
GO:0030790	biolink:NamedThing	chlorophenol O-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + trichlorophenol = S-adenosyl-L-homocysteine + trichloroanisole.	tmpzr1t_l9r_go_relaxed.owl	S-adenosyl-L-methionine:trichlorophenol O-methyltransferase activity|trichlorophenol O-methyltransferase activity|halogenated phenol O-methyltransferase activity				MetaCyc:2.1.1.136-RXN|RHEA:18909|EC:2.1.1.136									molecular_function											owl:Class	
GO:0051876	biolink:NamedThing	pigment granule dispersal	The directed movement of pigment granules within a cell towards the cell periphery.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0048061	biolink:NamedThing	positive gravitaxis	The directed movement of a motile cell or organism towards the source of gravity.	tmpzr1t_l9r_go_relaxed.owl	positive taxis in response to gravity|positive geotactic behavior|positive geotactic behaviour|positive taxis in response to gravitytaxis in response to gravitational stimulus|positive gravitactic behavior|positive gravitactic behaviour											GO:0048064		biological_process											owl:Class	
GO:0048375	biolink:NamedThing	negative regulation of lateral mesodermal cell fate determination	Any process that stops, prevents, or reduces the frequency, rate or extent of lateral mesoderm cell fate determination.	tmpzr1t_l9r_go_relaxed.owl	inhibition of lateral mesodermal cell fate determination|down regulation of lateral mesodermal cell fate determination|down-regulation of lateral mesodermal cell fate determination|downregulation of lateral mesodermal cell fate determination|negative regulation of lateral plate mesodermal cell fate determination													biological_process											owl:Class	
GO:0031053	biolink:NamedThing	primary miRNA processing	Any process involved in the conversion of a primary microRNA transcript into a pre-microRNA molecule.	tmpzr1t_l9r_go_relaxed.owl	primary microRNA processing|pri-miRNA processing													biological_process											owl:Class	
GO:0023028	biolink:NamedThing	MHC class I protein binding, via lateral surface	Binding to a major histocompatibility complex class I molecules via the lateral surface.	tmpzr1t_l9r_go_relaxed.owl									2010-02-16T09:30:50Z					molecular_function											owl:Class	
GO:0071562	biolink:NamedThing	nucleus-vacuole junction assembly	The aggregation, arrangement and bonding together of a set of components to form a nucleus-vacuole junction, which are membrane contact sites formed between the vacuole membrane and the outer nuclear membrane. In S. cerevisiae these contacts are mediated through direct physical interaction between Vac8p and Nvj1p.	tmpzr1t_l9r_go_relaxed.owl	NVJ formation|nucleus-vacuole junction formation|NV junction formation|NV junction assembly|NVJ assembly							mah	2010-01-20T02:16:36Z					biological_process											owl:Class	
GO:0033717	biolink:NamedThing	gluconate 2-dehydrogenase (acceptor) activity	Catalysis of the reaction: D-gluconate + acceptor = 2-dehydro-D-gluconate + reduced acceptor.	tmpzr1t_l9r_go_relaxed.owl	D-gluconate dehydrogenase activity|gluconate oxidase activity|2-ketogluconate reductase activity|gluconic acid dehydrogenase activity|gluconic dehydrogenase activity|D-gluconate dehydrogenase, 2-keto-D-gluconate-yielding activity|D-gluconate:(acceptor) 2-oxidoreductase activity|D-gluconate:acceptor 2-oxidoreductase activity				EC:1.1.99.3|RHEA:12769|MetaCyc:GLUCONATE-2-DEHYDROGENASE-RXN									molecular_function											owl:Class	
GO:0016403	biolink:NamedThing	dimethylargininase activity	Catalysis of the reaction: N(G),N(G)-dimethyl-L-arginine + H2O = dimethylamine + L-citrulline.	tmpzr1t_l9r_go_relaxed.owl	N(G),N(G)-dimethylarginine dimethylaminohydrolase activity|NG,NG-dimethyl-L-arginine dimethylamidohydrolase activity|dimethylarginine dimethylaminohydrolase activity|NG,NG-dimethylarginine dimethylaminohydrolase activity				EC:3.5.3.18|Reactome:R-HSA-5693373|RHEA:17305|MetaCyc:DIMETHYLARGININASE-RXN									molecular_function											owl:Class	
GO:0019669	biolink:NamedThing	anaerobic glycine catabolic process	The anaerobic chemical reactions and pathways resulting in the breakdown of glycine, yielding energy in the form of ATP.	tmpzr1t_l9r_go_relaxed.owl	glycine fermentation													biological_process											owl:Class	
GO:0050069	biolink:NamedThing	lysine dehydrogenase activity	Catalysis of the reaction: L-lysine + NAD+ = 1,2-didehydropiperidine-2-carboxylate + NH3 + NADH.	tmpzr1t_l9r_go_relaxed.owl	L-lysine:NAD+ oxidoreductase (deaminating, cyclizing)				RHEA:18505|MetaCyc:LYSINE-DEHYDROGENASE-RXN|EC:1.4.1.15									molecular_function											owl:Class	
GO:0102554	biolink:NamedThing	lipoyl synthase activity (acting on 2-oxoglutarate-dehydrogenase E2 protein	Catalysis of the reaction: 2 S-adenosyl-L-methionine  + a [2-oxoglutarate-dehydrogenase E2 protein] N6-octanoyl-L-lysine + 2 a sulfurated [sulfur carrier] = 2 L-methionine  + 2 5'-deoxyadenosine + 2 H+ + a [2-oxoglutarate dehydrogenase E2 protein] N6-lipoyl-L-lysine + 2 an unsulfurated [sulfur carrier].	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-14959									molecular_function											owl:Class	
GO:0016514	biolink:NamedThing	SWI/SNF complex	A SWI/SNF-type complex that contains 8 to 14 proteins, including both conserved (core) and nonconserved components; contains the ATPase product of the yeast SNF2 or mammalian SMARCA4/BAF190A/BRG1 gene, or an ortholog thereof.	tmpzr1t_l9r_go_relaxed.owl	SWI-SNF complex													cellular_component											owl:Class	
GO:0042806	biolink:NamedThing	fucose binding	Binding to fucose, the pentose 6-deoxygalactose.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0102205	biolink:NamedThing	cholesterol alpha-glucosyltransferase activity	Catalysis of the reaction: UDP-alpha-D-glucose + cholesterol = UDP + cholesteryl beta-D-glucoside + H+.	tmpzr1t_l9r_go_relaxed.owl	cholesterol UDP-glucosyltransferase activity|cholesterol allpha-glucosyltransferase activity				MetaCyc:RXN-12127|EC:2.4.1.173|RHEA:61848							GO:0051505		molecular_function											owl:Class	
GO:0010881	biolink:NamedThing	regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion	Any process that modulates the frequency, rate or extent of cardiac muscle contraction via the regulation of the release of sequestered calcium ion by sarcoplasmic reticulum into cytosol. The sarcoplasmic reticulum is the endoplasmic reticulum of striated muscle, specialised for the sequestration of calcium ions that are released upon receipt of a signal relayed by the T tubules from the neuromuscular junction.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0050473	biolink:NamedThing	arachidonate 15-lipoxygenase activity	Catalysis of the reaction: arachidonate + O2 = (5Z,8Z,11Z,13E)-(15S)-15-hydroperoxyicosa-5,8,11,13-tetraenoate.	tmpzr1t_l9r_go_relaxed.owl	15-lipoxygenase activity|arachidonate omega6 lipoxygenase activity|linoleic acid omega6-lipoxygenase activity|arachidonate:oxygen 15-oxidoreductase activity|omega6 lipoxygenase activity|arachidonate omega(6) lipoxygenase activity				Reactome:R-HSA-2162002|Reactome:R-HSA-9020275|Reactome:R-HSA-9028255|RHEA:16869|Reactome:R-HSA-9020262|Reactome:R-HSA-9018907|EC:1.13.11.33|Reactome:R-HSA-9026003|Reactome:R-HSA-9024872|Reactome:R-HSA-2161951|Reactome:R-HSA-9025152|Reactome:R-HSA-9027532|MetaCyc:ARACHIDONATE-15-LIPOXYGENASE-RXN|Reactome:R-HSA-9024881|Reactome:R-HSA-9020261|Reactome:R-HSA-9027607|Reactome:R-HSA-9027627|Reactome:R-HSA-9020610									molecular_function											owl:Class	
GO:0071186	biolink:NamedThing	protocadherin-alpha-v4-protocadherin-gamma-b2 complex	A protein complex that contains the cell adhesion molecules protocadherin-alpha-v4 and protocadherin-gamma-b2, and is involved in the regulation of protein localization to the plasma membrane.	tmpzr1t_l9r_go_relaxed.owl	Pcdhga1-Pcdhgb2 complex							mah	2009-11-23T04:21:33Z					cellular_component											owl:Class	
GO:0009423	biolink:NamedThing	chorismate biosynthetic process	The chemical reactions and pathways resulting in the formation of the unsymmetrical ether derived from phosphoenolpyruvate and 5-phosphoshikimic acid formed as an intermediate in the biosynthesis of aromatic amino acids and many other compounds.	tmpzr1t_l9r_go_relaxed.owl	chorismate formation|shikimate synthesis|shikimate pathway|shikimate anabolism|shikimate biosynthetic process|shikimate biosynthesis|chorismate synthesis|chorismate anabolism|chorismate biosynthesis				MetaCyc:ARO-PWY							GO:0033587		biological_process											owl:Class	
GO:0034958	biolink:NamedThing	aminohydroquinone monooxygenase activity	Catalysis of the reaction: aminohydroquinone + 2 e- + 2 H+ + 1/2 O2 = 1,2,4-benzenetriol + NH3.	tmpzr1t_l9r_go_relaxed.owl					EC:3.5.99.-|UM-BBD_reactionID:r1497									molecular_function											owl:Class	
GO:0008667	biolink:NamedThing	2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase activity	Catalysis of the reaction: (2S,3S)-2,3-dihydroxy-2,3-dihydrobenzoate + NAD(+) = 2,3-dihydroxybenzoate + H(+) + NADH.	tmpzr1t_l9r_go_relaxed.owl	2,3-dihydro-2,3-dihydroxybenzoate:NAD+ oxidoreductase activity|2,3-DHB dehydrogenase activity				KEGG_REACTION:R01505|EC:1.3.1.28|MetaCyc:DHBDEHYD-RXN|RHEA:23824									molecular_function											owl:Class	
GO:0044516	biolink:NamedThing	positive regulation of glucagon-like peptide receptor 1 activity in other organism	A process that activates or increases the frequency, rate or extent of the activity of a glucagon-like peptide receptor 1 in a second organism.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-02-26T11:09:44Z					biological_process											owl:Class	
GO:0098736	biolink:NamedThing	negative regulation of the force of heart contraction	Any process that decreases the force of heart muscle contraction.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0033154	biolink:NamedThing	ABC-type oligogalacturonide transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + oligogalacturonide(out) = ADP + phosphate + oligogalacturonide(in).	tmpzr1t_l9r_go_relaxed.owl	ATPase-coupled oligogalacturonide transmembrane transporter activity|oligogalacturonide transmembrane transporter activity|ATP-dependent oligogalacturonide transmembrane transporter activity|oligogalacturonide-transporting ATPase activity|oligogalacturonide transporting ATPase activity				TC:3.A.1.1.11							GO:0033155		molecular_function											owl:Class	
GO:0008442	biolink:NamedThing	3-hydroxyisobutyrate dehydrogenase activity	Catalysis of the reaction: 3-hydroxy-2-methylpropanoate + NAD+ = 2-methyl-3-oxopropanoate + NADH + H+.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-70885|RHEA:17681|MetaCyc:3-HYDROXYISOBUTYRATE-DEHYDROGENASE-RXN|Reactome:R-HSA-508473|EC:1.1.1.31									molecular_function											owl:Class	
GO:0097129	biolink:NamedThing	cyclin D2-CDK4 complex	A protein complex consisting of cyclin D2 and cyclin-dependent kinase 4 (CDK4). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner.	tmpzr1t_l9r_go_relaxed.owl								pr	2011-08-01T01:53:15Z					cellular_component											owl:Class	
GO:0000249	biolink:NamedThing	C-22 sterol desaturase activity	Catalysis of the formation of the C-22(23) double bond in the sterol side chain. An example reaction: 5,7,24(28)-ergostatrienol + O2 + NADPH = 5,7,22,24(28)-ergostatetraenol + 2 H2O + NADP+.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0047107	biolink:NamedThing	gamma-guanidinobutyraldehyde dehydrogenase activity	Catalysis of the reaction: 4-guanidinobutanal + H(2)O + NAD(+) = 4-guanidinobutanoate + 2 H(+) + NADH.	tmpzr1t_l9r_go_relaxed.owl	4-guanidinobutanal:NAD+ 1-oxidoreductase activity|alpha-guanidinobutyraldehyde dehydrogenase activity|4-guanidinobutyraldehyde dehydrogenase activity|GBAL dehydrogenase activity				KEGG_REACTION:R03177|RHEA:14381|EC:1.2.1.54|MetaCyc:1.2.1.54-RXN									molecular_function											owl:Class	
GO:0102588	biolink:NamedThing	cyanidin 3-O-glucoside 6''-O-malonyltransferase activity	Catalysis of the reaction: cyanidin 3-O-beta-D-glucoside betaine + malonyl-CoA <=> cyanidin 3-O-(6-O-malonyl-beta-D-glucoside) + coenzyme A.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-15335|EC:2.3.1.171									molecular_function											owl:Class	
GO:0030382	biolink:NamedThing	sperm mitochondrion organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of sperm mitochondria; the process in which they take on their characteristic morphology; they are flattened, elongated, and arranged circumferentially into a tight helical coil around the tail-dense fibers of the mature sperm.	tmpzr1t_l9r_go_relaxed.owl	sperm mitochondria organisation|sperm mitochondria organization and biogenesis|sperm mitochondrion organization and biogenesis													biological_process											owl:Class	
GO:0022620	biolink:NamedThing	vegetative cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a vegetative cell. The vegetative cell is gives rise to the pollen tube.	tmpzr1t_l9r_go_relaxed.owl	tube cell differentiation													biological_process											owl:Class	
GO:0001602	biolink:NamedThing	pancreatic polypeptide receptor activity	Combining with pancreatic polypeptide PP to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0004983	biolink:NamedThing	neuropeptide Y receptor activity	Combining with neuropeptide Y to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0072050	biolink:NamedThing	S-shaped body morphogenesis	The process in which the S-shaped body is generated and organized. The S-shaped body is the successor of the comma-shaped body that contributes to the morphogenesis of the nephron.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-01-25T03:45:19Z					biological_process											owl:Class	
GO:0071178	biolink:NamedThing	MAML2-RBP-Jkappa-ICN4 complex	A protein complex that consists of the intracellular domain of Notch4 (ICN4), the DNA-binding transcription factor RBP-Jkappa, and the transcriptional coactivator Mastermind-like-2 (MAML2); the complex is involved in transcriptional activation in response to Notch-mediated signaling.	tmpzr1t_l9r_go_relaxed.owl	MAML2-RBP-Jkappa-Notch4 complex							mah	2009-11-23T02:49:21Z					cellular_component											owl:Class	
GO:1903048	biolink:NamedThing	regulation of acetylcholine-gated cation channel activity	Any process that modulates the frequency, rate or extent of acetylcholine-gated cation channel activity.	tmpzr1t_l9r_go_relaxed.owl								bf	2014-05-22T14:46:53Z					biological_process											owl:Class	
GO:0019496	biolink:NamedThing	serine-isocitrate lyase pathway	A one-carbon metabolic process in which acetyl-CoA is produced from formaldehyde and carbon dioxide.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0006730	biolink:NamedThing	one-carbon metabolic process	The chemical reactions and pathways involving the transfer of one-carbon units in various oxidation states.	tmpzr1t_l9r_go_relaxed.owl	one-carbon metabolism|one-carbon transfer metabolism|one-carbon transfer metabolic process|one carbon metabolism|one carbon metabolic process				UM-BBD_pathwayID:C1cyc							GO:0019754|GO:0019753		biological_process											owl:Class	
GO:0070251	biolink:NamedThing	pristanate-CoA ligase activity	Catalysis of the reaction: ATP + pristanate + CoA = AMP + diphosphate + pristanoyl-CoA.	tmpzr1t_l9r_go_relaxed.owl	pristanoyl-CoA ligase activity|pristanate:CoA ligase (AMP-forming)				Reactome:R-HSA-389632|RHEA:47264									molecular_function											owl:Class	
GO:0102377	biolink:NamedThing	steviol 13-O glucosyltransferase activity	Catalysis of the reaction: steviol + UDP-alpha-D-glucose = steviolmonoside + UDP + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-13511									molecular_function											owl:Class	
GO:1902223	biolink:NamedThing	erythrose 4-phosphate/phosphoenolpyruvate family amino acid biosynthetic process	The chemical reactions and pathways resulting in the formation of erythrose 4-phosphate/phosphoenolpyruvate family amino acid.	tmpzr1t_l9r_go_relaxed.owl	erythrose 4-phosphate/phosphoenolpyruvate family amino acid synthesis|erythrose 4-phosphate/phosphoenolpyruvate family amino acid biosynthesis|erythrose 4-phosphate/phosphoenolpyruvate family amino acid formation|erythrose 4-phosphate/phosphoenolpyruvate family amino acid anabolism							pr	2013-06-13T10:37:49Z					biological_process											owl:Class	
GO:0097327	biolink:NamedThing	response to antineoplastic agent	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antineoplastic agent stimulus. An antineoplastic agent is a substance that inhibits or prevents the proliferation of neoplasms.	tmpzr1t_l9r_go_relaxed.owl								pr	2012-06-12T10:48:28Z					biological_process											owl:Class	
GO:0042000	biolink:NamedThing	translocation of peptides or proteins into host	The directed movement of peptides or proteins produced by an organism to a location inside its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	transport of peptides or proteins into host|translocation of peptides or proteins into other organism involved in symbiotic interaction|transport of peptides or proteins into other organism during symbiotic interaction|translocation of peptides or proteins into other organism during symbiotic interaction											GO:0051808		biological_process											owl:Class	
GO:0120197	biolink:NamedThing	mucociliary clearance	The respiratory system process driven by motile cilia on epithelial cells of the respiratory tract by which mucus and associated inhaled particles and pathogens trapped within it are moved out of the airways.	tmpzr1t_l9r_go_relaxed.owl	MCC|MCT|mucociliary transport							krc	2019-04-26T16:16:50Z					biological_process											owl:Class	
GO:0047959	biolink:NamedThing	glycine dehydrogenase (cytochrome) activity	Catalysis of the reaction: glycine + H2O + 2 ferricytochrome c = glyoxylate + NH3 + 2 ferrocytochrome c.	tmpzr1t_l9r_go_relaxed.owl	glycine:ferricytochrome-c oxidoreductase (deaminating)|reductase, glycine-cytochrome c|glycine-cytochrome c reductase activity				RHEA:16909|MetaCyc:GLYCINE-DEHYDROGENASE-CYTOCHROME-RXN|EC:1.4.2.1									molecular_function											owl:Class	
GO:0016640	biolink:NamedThing	oxidoreductase activity, acting on the CH-NH2 group of donors, cytochrome as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH2 group acts as a hydrogen or electron donor and reduces a cytochrome molecule.	tmpzr1t_l9r_go_relaxed.owl					EC:1.4.2.-									molecular_function											owl:Class	
GO:0102463	biolink:NamedThing	quercetin 3-gentiobioside 7-O-rhamnosyltransferase activity	Catalysis of the reaction: quercetin-3-gentiobioside + UDP-L-rhamnose <=> quercetin 3-O-gentiobioside-7-O-rhamnoside + UDP + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-14012									molecular_function											owl:Class	
GO:0003304	biolink:NamedThing	myocardial epithelial involution involved in heart jogging	The morphogenetic process in which the myocardium bends along a linear axis and contributes to the process of heart jogging.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-10-22T11:03:33Z					biological_process											owl:Class	
GO:0000476	biolink:NamedThing	maturation of 4.5S rRNA	Any process involved in the maturation of a precursor 4.5S ribosomal RNA (rRNA) molecule into a mature 4.5S rRNA molecule.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1902084	biolink:NamedThing	fumagillin metabolic process	The chemical reactions and pathways involving fumagillin.	tmpzr1t_l9r_go_relaxed.owl	fumagillin metabolism							di	2013-04-25T14:00:41Z					biological_process											owl:Class	
GO:0070626	biolink:NamedThing	(S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido) succinate lyase (fumarate-forming) activity	Catalysis of the reaction: (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate = fumarate + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide.	tmpzr1t_l9r_go_relaxed.owl	succino AMP-lyase activity|SAICAR-lyase (fumarate forming) activity|(S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity|adenylosuccinase activity|adenylosuccinate lyase activity				KEGG_REACTION:R04559|EC:4.3.2.2|MetaCyc:AICARSYN-RXN|RHEA:23920			mah	2009-05-01T04:13:49Z					molecular_function											owl:Class	
GO:0102538	biolink:NamedThing	UDP-N-acetyl-alpha-D-quinovosamine dehydrogenase activity	Catalysis of the reaction: UDP-N-acetyl-alpha-D-quinovosamine + NAD(P) = UDP-2-acetamido-4-dehydro-2,6-dideoxy-beta-D-glucose + H+ + NAD(P)H.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-14767									molecular_function											owl:Class	
GO:0046988	biolink:NamedThing	asioloorosomucoid beta-1,3-glucuronosyltransferase activity	Catalysis of the transfer, in a beta 1,3 linkage, of D-glucuronic acid (GlcUA) from UDP-GlcUA to asioloorosomucoid.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0008894	biolink:NamedThing	guanosine-5'-triphosphate,3'-diphosphate diphosphatase activity	Catalysis of the reaction: guanosine 5'-triphosphate,3'-diphosphate + H2O = guanosine 5'-diphosphate,3'-diphosphate + phosphate.	tmpzr1t_l9r_go_relaxed.owl	guanosine-5'-triphosphate,3'-diphosphate 5'-phosphohydrolase activity|pppGpp 5'-phosphohydrolase activity|guanosine 5'-triphosphate-3'-diphosphate 5'-phosphohydrolase activity|guanosine 5'-triphosphate 3'-diphosphate 5'-phosphatase activity|guanosine pentaphosphatase activity|guanosine pentaphosphate phosphatase activity|guanosine pentaphosphate phosphohydrolase activity|guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase activity				MetaCyc:PPPGPPHYDRO-RXN|RHEA:13073|EC:3.6.1.40									molecular_function											owl:Class	
GO:0007536	biolink:NamedThing	activation of recombination (HML)	The activation of recombination at a mating type locus, such that it is used in preference to the other donor locus for mating type switching; exemplified by the HML locus and surrounding sequences on Chromosome III in Saccharomyces cerevisiae.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0008179	biolink:NamedThing	adenylate cyclase binding	Binding to an adenylate cyclase.	tmpzr1t_l9r_go_relaxed.owl	adenylyl cyclase binding				Reactome:R-HSA-170672									molecular_function											owl:Class	
GO:0097383	biolink:NamedThing	dIDP diphosphatase activity	Catalysis of the reaction: dIDP + H2O = dIMP + phosphate.	tmpzr1t_l9r_go_relaxed.owl	deoxyinosine-diphosphatase activity				RHEA:35211|Reactome:R-HSA-2509793			pr	2012-10-11T16:04:40Z					molecular_function											owl:Class	
GO:0097382	biolink:NamedThing	deoxynucleoside-diphosphatase activity	Catalysis of the reaction: a deoxynucleoside diphosphate + H2O = a deoxynucleotide + phosphate.	tmpzr1t_l9r_go_relaxed.owl								pr	2012-10-11T16:03:22Z					molecular_function											owl:Class	
GO:0071068	biolink:NamedThing	alpha9-beta1 integrin-ADAM12 complex	A protein complex that consists of an alpha9-beta1 integrin complex bound to the transmembrane metallopeptidase ADAM12.	tmpzr1t_l9r_go_relaxed.owl	ITGA9-ITGB1-ADAM12 complex							mah	2009-11-03T04:05:15Z					cellular_component											owl:Class	
GO:0050149	biolink:NamedThing	o-aminophenol oxidase activity	Catalysis of the reaction: 2 2-aminophenol + 3 O2 = 2 isophenoxazine + 6 H2O.	tmpzr1t_l9r_go_relaxed.owl	o-aminophenol:O2 oxidoreductase activity|isophenoxazine synthase activity|2-aminophenol:O2 oxidoreductase activity|GriF|2-aminophenol:oxygen oxidoreductase activity				MetaCyc:O-AMINOPHENOL-OXIDASE-RXN|EC:1.10.3.4|RHEA:40963									molecular_function											owl:Class	
GO:0047136	biolink:NamedThing	4-(dimethylamino)phenylazoxybenzene reductase activity	Catalysis of the reaction: 4-(dimethylamino)azobenzene + H(2)O + NADP(+) = 4-(dimethylamino)phenylazoxybenzene + H(+) + NADPH.	tmpzr1t_l9r_go_relaxed.owl	NADPH-dependent DMAB N-oxide reductase activity|NADPH2:4-(dimethylamino)phenylazoxybenzene oxidoreductase activity|4-(dimethylamino)phenylazobenzene:NADP+ oxidoreductase activity|dimethylaminoazobenzene N-oxide reductase activity|NADPH:4-(dimethylamino)phenylazoxybenzene oxidoreductase activity|N,N-dimethyl-p-aminoazobenzene oxide reductase activity				MetaCyc:1.6.6.12-RXN|EC:1.7.1.11|KEGG_REACTION:R04303|RHEA:19789									molecular_function											owl:Class	
GO:0060489	biolink:NamedThing	planar dichotomous subdivision of terminal units involved in lung branching morphogenesis	The process in which a lung bud bifurcates parallel to the plane of the previous bud.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0047683	biolink:NamedThing	aryl-aldehyde dehydrogenase (NADP+) activity	Catalysis of the reaction: an aromatic aldehyde + NADP+ + AMP + diphosphate + H2O = an aromatic acid + NADPH + ATP.	tmpzr1t_l9r_go_relaxed.owl	aryl-aldehyde:NADP+ oxidoreductase (ATP-forming)|aromatic acid reductase activity				MetaCyc:ARYL-ALDEHYDE-DEHYDROGENASE-NADP+-RXN|EC:1.2.1.30|RHEA:19229									molecular_function											owl:Class	
GO:0009429	biolink:NamedThing	bacterial-type flagellum basal body, proximal rod	The portion of the central rod of the bacterial-type flagellar basal body that is proximal to the cell membrane; the proximal rod connects the distal rod to the flagellar motor.	tmpzr1t_l9r_go_relaxed.owl	flagellar basal body, proximal rod|flagellin-based flagellum basal body, proximal rod													cellular_component											owl:Class	
GO:0070978	biolink:NamedThing	voltage-gated calcium channel complex assembly	Cellular protein complex assembly that results in the formation of a voltage-gated calcium channel complex.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-10-06T04:51:13Z					biological_process											owl:Class	
GO:0016520	biolink:NamedThing	growth hormone-releasing hormone receptor activity	Combining with growth hormone-releasing hormone to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0019935	biolink:NamedThing	cyclic-nucleotide-mediated signaling	Any intracellular signal transduction in which the signal is passed on within the cell via a cyclic nucleotide. Includes production or release of the cyclic nucleotide, and downstream effectors that further transmit the signal within the cell.	tmpzr1t_l9r_go_relaxed.owl	cyclic-nucleotide-mediated signalling													biological_process											owl:Class	
GO:0008566	biolink:NamedThing	mitochondrial protein-transporting ATPase activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O = ADP + phosphate; drives the transport of proteins into the mitochondrion via the mitochondrial inner membrane translocase complex.	tmpzr1t_l9r_go_relaxed.owl	ATPase-coupled mitochondrial protein transporter activity				MetaCyc:3.6.3.51-RXN|EC:7.4.2.3	See also the cellular component term 'mitochondrial inner membrane presequence translocase complex ; GO:0005744'.								molecular_function											owl:Class	
GO:0102264	biolink:NamedThing	tRNA-dihydrouridine20 synthase activity	Catalysis of the reaction: a 5,6-dihydrouracil20 in tRNA + NAD(P) <=> H+ + a uracil20 in tRNA + NAD(P)H.	tmpzr1t_l9r_go_relaxed.owl					EC:1.3.1.91|MetaCyc:RXN-12456									molecular_function											owl:Class	
GO:0102118	biolink:NamedThing	gibberellin A4 carboxyl methyltransferase activity	Catalysis of the reaction: gibberellin A4 + S-adenosyl-L-methionine  <=> gibberellin A4 methyl ester + S-adenosyl-L-homocysteine.	tmpzr1t_l9r_go_relaxed.owl					RHEA:36107|MetaCyc:RXN-11359|EC:2.1.1.276									molecular_function											owl:Class	
GO:1905079	biolink:NamedThing	regulation of cerebellar neuron development	Any process that modulates the frequency, rate or extent of cerebellar neuron development.	tmpzr1t_l9r_go_relaxed.owl								hjd	2016-03-24T19:45:17Z					biological_process											owl:Class	
GO:0098579	biolink:NamedThing	active sex chromosome	A sex chromosome that has not been inactivated.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0033991	biolink:NamedThing	aldos-2-ulose dehydratase activity	Catalysis of the reactions: 1,5-anhydro-D-fructose = 2-hydroxy-2-(hydroxymethyl)-2H-pyran-3(6H)-one + H2O; (1a) 1,5-anhydro-D-fructose = 1,5-anhydro-4-deoxy-D-glycero-hex-3-en-2-ulose + H2O and (1b) 1,5-anhydro-4-deoxy-D-glycero-hex-3-en-2-ulose = 2-hydroxy-2-(hydroxymethyl)-2H-pyran-3(6H)-one.	tmpzr1t_l9r_go_relaxed.owl	1,5-anhydro-D-fructose hydro-lyase (microthecin-forming) activity|1,5-anhydro-D-fructose dehydratase (microthecin-forming) activity|AUDH|pyranosone dehydratase activity				RHEA:12100|MetaCyc:4.2.1.110-RXN|EC:4.2.1.110									molecular_function											owl:Class	
GO:0019871	biolink:NamedThing	sodium channel inhibitor activity	Binds to and stops, prevents, or reduces the activity of a sodium channel.	tmpzr1t_l9r_go_relaxed.owl												GO:0019868		molecular_function											owl:Class	
GO:0052766	biolink:NamedThing	mannoside alpha-1,4-mannosidase activity	Catalysis of the hydrolysis of the alpha-(1->4) linkage of the terminal, non-reducing alpha-D-mannose residues in alpha-D-mannosides.	tmpzr1t_l9r_go_relaxed.owl	mannoside alpha-1,4-exomannosidase activity|alpha-1,4-exomannosidase activity|mannoside exo-alpha-1,4-mannosidase activity|alpha-1,4-mannosidase activity							ai	2011-09-30T12:55:24Z					molecular_function											owl:Class	
GO:0030285	biolink:NamedThing	integral component of synaptic vesicle membrane	The component of the synaptic vesicle membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.	tmpzr1t_l9r_go_relaxed.owl	integral to synaptic vesicle membrane													cellular_component											owl:Class	
GO:0051787	biolink:NamedThing	misfolded protein binding	Binding to a misfolded protein.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-5324632									molecular_function											owl:Class	
GO:0018596	biolink:NamedThing	dimethylsilanediol hydroxylase activity	Catalysis of the reaction: dimethylsilanediol + O2 + 2 H+ + 2 e- = H2O + hydroxymethylmethylsilanediol.	tmpzr1t_l9r_go_relaxed.owl	DMSD hydroxylase activity				UM-BBD_reactionID:r0637									molecular_function											owl:Class	
GO:0034797	biolink:NamedThing	fosfomycin 2-glutathione ligase activity	Catalysis of the reaction: hydrogen (2R,3S)-3-methyloxiran-2-ylphosphonic acid + glutathione = hydrogen (1R,2R)-1-glutathio-2-hydroxypropylphosphonic acid.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r1073									molecular_function											owl:Class	
GO:0044083	biolink:NamedThing	modulation by symbiont of host Rho protein signal transduction	Any process in which a symbiont organism modulates the frequency, rate or extent of Rho protein signal transduction in its host organism.	tmpzr1t_l9r_go_relaxed.owl	modulation by symbiont of host Rho protein-mediated signal transduction|modulation by symbiont of host Rho protein mediated signal transduction|modulation of host Rho protein signaling by symbiont|regulation by symbiont of host Rho protein signal transduction|modulation of host Rho protein signal transduction by symbiont|modulation of host Rho protein signalling by symbiont													biological_process											owl:Class	
GO:0015652	biolink:NamedThing	quaternary ammonium group:proton symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: quaternary ammonium group(out) + H+(out) = quaternary ammonium group(in) + H+(in).	tmpzr1t_l9r_go_relaxed.owl	quaternary ammonium group:hydrogen symporter activity													molecular_function											owl:Class	
GO:0033323	biolink:NamedThing	choline biosynthetic process via CDP-choline	The chemical reactions and pathways resulting in the formation of choline (2-hydroxyethyltrimethylammonium), via the intermediate CDP-choline.	tmpzr1t_l9r_go_relaxed.owl	choline biosynthesis via CDP-choline|choline formation via CDP-choline|choline synthesis via CDP-choline|choline anabolism via CDP-choline				MetaCyc:PWY-4762|MetaCyc:PWY-3561									biological_process											owl:Class	
GO:1902728	biolink:NamedThing	positive regulation of growth factor dependent skeletal muscle satellite cell proliferation	Any process that activates or increases the frequency, rate or extent of satellite cell proliferation; dependent on specific growth factor activity such as fibroblast growth factors and transforming growth factor beta.	tmpzr1t_l9r_go_relaxed.owl								mr	2014-02-24T16:10:33Z					biological_process											owl:Class	
GO:2000287	biolink:NamedThing	positive regulation of myotome development	Any process that activates or increases the frequency, rate or extent of myotome development.	tmpzr1t_l9r_go_relaxed.owl								rl	2010-12-16T05:17:15Z					biological_process											owl:Class	
GO:0052712	biolink:NamedThing	inositol phosphosphingolipid phospholipase activity	Catalysis of the reaction: inositol phosphosphingolipid + H2O = sphingolipid + phosphorylinositol.	tmpzr1t_l9r_go_relaxed.owl								ai	2011-08-05T04:49:13Z					molecular_function											owl:Class	
GO:0055079	biolink:NamedThing	aluminum ion homeostasis	Any process involved in the maintenance of an internal steady state of aluminum ions within an organism or cell.	tmpzr1t_l9r_go_relaxed.owl	aluminium ion homeostasis													biological_process											owl:Class	
GO:0043817	biolink:NamedThing	phosphosulfolactate synthase activity	Catalysis of the reaction: (2R)-O-phospho-3-sulfolactate = phosphoenolpyruvate + sulfite.	tmpzr1t_l9r_go_relaxed.owl	(2R)-O-phospho-3-sulfolactate sulfo-lyase activity|(2R)-phospho-3-sulfolactate synthase activity|PSL synthase activity|(2R)-O-phospho-3-sulfolactate sulfo-lyase (phosphoenolpyruvate-forming)				EC:4.4.1.19|RHEA:22784|MetaCyc:R228-RXN|MetaCyc:4.4.1.19-RXN|KEGG_REACTION:R07476									molecular_function											owl:Class	
GO:1901908	biolink:NamedThing	diadenosine hexaphosphate metabolic process	The chemical reactions and pathways involving diadenosine hexaphosphate.	tmpzr1t_l9r_go_relaxed.owl	diadenosyl hexaphosphate metabolism|diadenosine hexaphosphate metabolism|diadenosyl hexaphosphate metabolic process							al	2013-02-13T13:50:40Z					biological_process											owl:Class	
GO:0030507	biolink:NamedThing	spectrin binding	Binding to spectrin, a protein that is the major constituent of the erythrocyte cytoskeletal network. It associates with band 4.1 (see band protein) and actin to form the cytoskeletal superstructure of the erythrocyte plasma membrane. It is composed of nonhomologous chains, alpha and beta, which aggregate side-to-side in an antiparallel fashion to form dimers, tetramers, and higher polymers.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1902258	biolink:NamedThing	positive regulation of apoptotic process involved in outflow tract morphogenesis	Any process that activates or increases the frequency, rate or extent of apoptotic process involved in outflow tract morphogenesis.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of apoptotic process involved in outflow tract morphogenesis|up-regulation of apoptosis involved in outflow tract morphogenesis|activation of apoptosis involved in outflow tract morphogenesis|activation of apoptotic process involved in outflow tract morphogenesis|upregulation of apoptotic process involved in outflow tract morphogenesis|upregulation of apoptosis involved in outflow tract morphogenesis|up regulation of apoptosis involved in outflow tract morphogenesis|up regulation of apoptotic process involved in outflow tract morphogenesis|positive regulation of apoptosis involved in outflow tract morphogenesis							dph	2013-06-24T19:12:42Z					biological_process											owl:Class	
GO:1902711	biolink:NamedThing	GABA-A receptor complex	A protein complex which is capable of GABA-A receptor activity. In human, it is usually composed of either two alpha, two beta and one gamma chain of the GABA-A receptor subunits or 5 chains of the GABA-A receptor subunits rho1-3 (formally known as GABA-C receptor).	tmpzr1t_l9r_go_relaxed.owl						An example of this is GBRA1 in human (UniProt symbol P14867) in PMID:18790874.		bhm	2014-02-21T09:19:58Z					cellular_component											owl:Class	
GO:2000743	biolink:NamedThing	negative regulation of anterior head development	Any process that stops, prevents or reduces the frequency, rate or extent of anterior head development.	tmpzr1t_l9r_go_relaxed.owl								yaf	2011-06-14T09:44:14Z					biological_process											owl:Class	
GO:0018470	biolink:NamedThing	4-hydroxybutaraldehyde dehydrogenase activity	Catalysis of the reaction: 4-hydroxybutyraldehyde + H2O = 2 H+ + 2 e- + 4-hydroxybutanoate.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0014									molecular_function											owl:Class	
GO:0031208	biolink:NamedThing	POZ domain binding	Binding to a POZ (poxvirus and zinc finger) domain of a protein, a protein-protein interaction domain found in many transcription factors.	tmpzr1t_l9r_go_relaxed.owl	BTB domain|broad-complex, tramtrack, and bric-a-brac domain binding													molecular_function											owl:Class	
GO:0003833	biolink:NamedThing	beta-alanyl-dopamine synthase activity	Catalysis of the synthesis of beta-alanyl-dopamine from the precursor dopamine (3,4-dihydroxyphenylethylamine).	tmpzr1t_l9r_go_relaxed.owl	N-beta-alanyl dopamine synthetase activity|NBAD transferase activity													molecular_function											owl:Class	
GO:0019161	biolink:NamedThing	diamine transaminase activity	Catalysis of the reaction: an alpha,omega-diamine + 2-oxoglutarate = an omega-aminoaldehyde + L-glutamate.	tmpzr1t_l9r_go_relaxed.owl	diamine-ketoglutaric transaminase activity|diamine aminotransferase activity|diamine:2-oxoglutarate aminotransferase activity|amine transaminase activity|amine-ketoacid transaminase activity				MetaCyc:DIAMTRANSAM-RXN|RHEA:18217|EC:2.6.1.29									molecular_function											owl:Class	
GO:0030735	biolink:NamedThing	carnosine N-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + carnosine = S-adenosyl-L-homocysteine + anserine + H(+).	tmpzr1t_l9r_go_relaxed.owl	S-adenosyl-L-methionine:carnosine N-methyltransferase activity				KEGG_REACTION:R02144|EC:2.1.1.22|RHEA:14205|Reactome:R-HSA-8876789|MetaCyc:CARNOSINE-N-METHYLTRANSFERASE-RXN									molecular_function											owl:Class	
GO:0070533	biolink:NamedThing	BRCA1-C complex	A protein complex that contains the BRCA1-BARD1 heterodimer, CtIP and Mre11/Rad50/NBS1 (M/R/N) complex, and binds to DNA at DNA damage sites. BRCA1-C binding ta damaged DNA is required for DNA damage-induced Chk1 phosphorylation and the G2/M transition checkpoint.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0048238	biolink:NamedThing	smooth endoplasmic reticulum lumen	The volume enclosed by the membranes of the smooth endoplasmic reticulum.	tmpzr1t_l9r_go_relaxed.owl	smooth ER lumen|SER lumen				NIF_Subcellular:sao927884761									cellular_component											owl:Class	
GO:0102031	biolink:NamedThing	4-acetamido-4,6-dideoxy-D-galactose transferase activity	Catalysis of the reaction: dTDP-4-acetamido-4,6-dideoxy-alpha-D-galactose + beta-D-ManNAcA-(1->4)-alpha-D-GlcNAc-1-diphospho-ditrans,polycis-undecaprenol <=> H+ + alpha-D-FucNAc4-(1->4)-beta-D-ManNAcA-(1->4)-D-GlcNAc-undecaprenyl diphosphate + dTDP.	tmpzr1t_l9r_go_relaxed.owl					RHEA:28759|EC:2.4.1.325|MetaCyc:FUC4NACTRANS-RXN									molecular_function											owl:Class	
GO:1903905	biolink:NamedThing	positive regulation of establishment of T cell polarity	Any process that activates or increases the frequency, rate or extent of establishment of T cell polarity.	tmpzr1t_l9r_go_relaxed.owl	upregulation of T lymphocyte polarization|up-regulation of T-cell polarization|positive regulation of establishment of T-cell polarity|up-regulation of establishment of T lymphocyte polarity|upregulation of T-cell polarization|upregulation of T cell polarization|positive regulation of T-cell polarization|upregulation of establishment of T-lymphocyte polarity|activation of establishment of T cell polarity|up regulation of T cell polarization|up-regulation of establishment of T cell polarity|up regulation of establishment of T cell polarity|up-regulation of T lymphocyte polarization|activation of T cell polarization|positive regulation of T lymphocyte polarization|up regulation of establishment of T-lymphocyte polarity|positive regulation of establishment of T lymphocyte polarity|up regulation of establishment of T-cell polarity|activation of T-cell polarization|positive regulation of T cell polarization|up regulation of T lymphocyte polarization|up regulation of establishment of T lymphocyte polarity|activation of establishment of T-cell polarity|upregulation of establishment of T lymphocyte polarity|activation of establishment of T-lymphocyte polarity|up-regulation of T cell polarization|activation of T lymphocyte polarization|up regulation of T-cell polarization|up-regulation of establishment of T-cell polarity|upregulation of establishment of T-cell polarity|up-regulation of establishment of T-lymphocyte polarity|activation of establishment of T lymphocyte polarity|upregulation of establishment of T cell polarity|positive regulation of establishment of T-lymphocyte polarity							als	2015-02-09T10:50:40Z					biological_process											owl:Class	
GO:1901749	biolink:NamedThing	leukotriene D4 catabolic process	The chemical reactions and pathways resulting in the breakdown of leukotriene D4.	tmpzr1t_l9r_go_relaxed.owl	leukotriene D4 degradation|leukotriene D4 catabolism|leukotriene D4 breakdown							yaf	2013-01-14T10:56:17Z					biological_process											owl:Class	
GO:0071658	biolink:NamedThing	regulation of IP-10 production	Any process that modulates the frequency, rate, or extent of production of IP-10.	tmpzr1t_l9r_go_relaxed.owl	regulation of chemokine (C-C motif) ligand 10 production|regulation of CXCL10 production							mah	2010-02-12T10:41:14Z					biological_process											owl:Class	
GO:0008948	biolink:NamedThing	oxaloacetate decarboxylase activity	Catalysis of the reaction: oxaloacetate = pyruvate + CO2.	tmpzr1t_l9r_go_relaxed.owl	oxaloacetate carboxy-lyase (pyruvate-forming)|oxalate beta-decarboxylase activity|oxalacetic acid decarboxylase activity|oxaloacetate carboxy-lyase activity|oxaloacetate beta-decarboxylase activity				MetaCyc:OXALODECARB-RXN|EC:1.1.1.38|EC:1.1.1.40|EC:4.1.1.112|Reactome:R-HSA-9012016|KEGG_REACTION:R00217|RHEA:15641									molecular_function											owl:Class	
GO:1904270	biolink:NamedThing	pyroptosome complex assembly	The aggregation, arrangement and bonding together of a set of components to form a pyroptosome complex.	tmpzr1t_l9r_go_relaxed.owl	ASC pyroptosome assembly|pyroptosome complex formation|ASC pyroptosome formation							lb	2015-05-29T08:25:45Z					biological_process											owl:Class	
GO:0043512	biolink:NamedThing	inhibin A complex	Heterodimeric hormone composed of an inhibin alpha subunit complexed with an inhibin beta-A subunit.	tmpzr1t_l9r_go_relaxed.owl						Note that the actions of the inhibin complex are the opposite of those of the activin complex, which is a dimer of an inhibin beta-A and/or inhibin beta-B subunit. See also the cellular component term 'activin complex ; GO:0048180'.								cellular_component											owl:Class	
GO:0019860	biolink:NamedThing	uracil metabolic process	The chemical reactions and pathways involving uracil, 2,4-dioxopyrimidine, one of the pyrimidine bases occurring in RNA, but not in DNA.	tmpzr1t_l9r_go_relaxed.owl	uracil metabolism													biological_process											owl:Class	
GO:0090294	biolink:NamedThing	nitrogen catabolite activation of transcription	A transcription regulation process in which the presence of one nitrogen source leads to an increase in the frequency, rate, or extent of transcription of specific genes involved in the metabolism of other nitrogen sources.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of transcription by nitrogen catabolites							tb	2010-02-24T02:31:53Z					biological_process											owl:Class	
GO:0019917	biolink:NamedThing	peptidyl-D-alanine racemization via peptidyl-L-serine	The dehydration of peptidyl-serine, followed by hydrogenation to produce peptidyl-D-alanine.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0191									biological_process											owl:Class	
GO:0031179	biolink:NamedThing	peptide modification	The covalent alteration of one or more amino acid residues within a peptide, resulting in a change in the properties of that peptide.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0070149	biolink:NamedThing	mitochondrial glutamyl-tRNA aminoacylation	The process of coupling glutamate to glutamyl-tRNA in a mitochondrion, catalyzed by glutamyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0006424	biolink:NamedThing	glutamyl-tRNA aminoacylation	The process of coupling glutamate to glutamyl-tRNA, catalyzed by glutamyl-tRNA synthetase. The glutamyl-tRNA synthetase is a  class-I synthetase. The activated amino acid is transferred to the 2'-OH group of a glutamic acid-accetping tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1903572	biolink:NamedThing	positive regulation of protein kinase D signaling	Any process that activates or increases the frequency, rate or extent of protein kinase D signaling.	tmpzr1t_l9r_go_relaxed.owl	activation of PKD signal transduction|up-regulation of PKD signaling cascade|up-regulation of protein kinase D signaling|up regulation of protein kinase D signal transduction|upregulation of protein kinase D signaling cascade|upregulation of PKD signal transduction|up regulation of PKD signal transduction|positive regulation of protein kinase D signal transduction|activation of PKD signaling cascade|up-regulation of PKD signal transduction|positive regulation of PKD signal transduction|activation of protein kinase D signaling cascade|positive regulation of protein kinase D signalling cascade|positive regulation of protein kinase D signaling cascade|upregulation of protein kinase D signaling|up-regulation of protein kinase D signal transduction|upregulation of protein kinase D signalling cascade|up regulation of PKD signaling cascade|activation of protein kinase D signalling cascade|upregulation of PKD signaling cascade|upregulation of protein kinase D signal transduction|activation of protein kinase D signaling|up-regulation of protein kinase D signalling cascade|activation of protein kinase D signal transduction|up regulation of protein kinase D signalling cascade|up regulation of protein kinase D signaling cascade|up-regulation of protein kinase D signaling cascade|positive regulation of PKD signaling cascade|up regulation of protein kinase D signaling							rl	2014-10-27T15:18:18Z					biological_process											owl:Class	
GO:0072754	biolink:NamedThing	cellular response to purvalanol A	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a purvalanol A stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2012-11-07T12:05:57Z					biological_process											owl:Class	
GO:1901560	biolink:NamedThing	response to purvalanol A	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a purvalanol A stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2012-11-02T15:32:28Z					biological_process											owl:Class	
GO:0007355	biolink:NamedThing	anterior region determination	Specification of the anterior (head and thoracic segments) of the embryo by the gap genes; exemplified in insects by the actions of hunchback gene product.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0075038	biolink:NamedThing	negative regulation of appressorium maturation	Any process that stops, prevents, or reduces the frequency, rate or extent symbiont appressorium maturation.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of maturation of appressorium on or near host|negative regulation of appressorium maturation on or near host													biological_process											owl:Class	
GO:0062151	biolink:NamedThing	catalase complex	A protein-containing complex that is capable of catalase activity.	tmpzr1t_l9r_go_relaxed.owl								dph	2019-09-17T12:18:02Z					cellular_component											owl:Class	
GO:0035617	biolink:NamedThing	stress granule disassembly	The disaggregation of a stress granule into its constituent protein and RNA parts.	tmpzr1t_l9r_go_relaxed.owl	SG disassembly							bf	2010-12-03T10:38:57Z					biological_process											owl:Class	
GO:0090363	biolink:NamedThing	regulation of proteasome core complex assembly	Any process that modulates the rate, frequency, or extent of the aggregation, arrangement and bonding together of a mature, active 20S proteasome core particle complex that does not contain any regulatory particles.	tmpzr1t_l9r_go_relaxed.owl								tb	2010-07-12T10:48:57Z					biological_process											owl:Class	
GO:0018120	biolink:NamedThing	peptidyl-arginine ADP-ribosylation	The transfer, from NAD, of ADP-ribose to peptidyl-arginine to form omega-N-(ADP-ribosyl)-L-arginine.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0168									biological_process											owl:Class	
GO:0047911	biolink:NamedThing	galacturan 1,4-alpha-galacturonidase activity	Catalysis of the reaction: [(1->4)-alpha-D-galacturonide](n) + H2O = [(1->4)-alpha-D-galacturonide](n-1) + D-galacturonate.	tmpzr1t_l9r_go_relaxed.owl	exo-D-galacturonase activity|exo-polygalacturonase activity|exo-D-galacturonanase activity|poly(1,4-alpha-D-galacturonide) galacturonohydrolase activity|exopolygalacturonase activity|exopoly-D-galacturonase activity|galacturan alpha-1,4-galacturonidase activity|poly(galacturonate) hydrolase activity				MetaCyc:GALACTURAN-14-ALPHA-GALACTURONIDASE-RXN|RHEA:14117|EC:3.2.1.67									molecular_function											owl:Class	
GO:0001762	biolink:NamedThing	beta-alanine transport	The directed movement of beta-alanine, 3-aminopropanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0001080	biolink:NamedThing	nitrogen catabolite activation of transcription from RNA polymerase II promoter	A transcription regulation process in which the presence of one nitrogen source leads to an increase in the frequency, rate, or extent of transcription, from an RNA polymerase II promoter, of specific genes involved in the metabolism of other nitrogen sources.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of transcription from RNA polymerase II promoter by nitrogen catabolites							krc	2010-10-27T03:32:34Z					biological_process											owl:Class	
GO:0051730	biolink:NamedThing	GTP-dependent polyribonucleotide 5'-hydroxyl-kinase activity	Catalysis of the reaction: GTP + 5'-dephospho-RNA = GDP + 5'-phospho-RNA.	tmpzr1t_l9r_go_relaxed.owl	GTP-dependent RNA kinase activity|GTP-dependent RNA 5'-hydroxyl-kinase activity|GTP:5'-dephosphopolyribonucleotide 5'-phosphotransferase activity|GTP-dependent polynucleotide 5'-hydroxyl-kinase activity|GTP-dependent polyribonucleotide kinase activity													molecular_function											owl:Class	
GO:0034584	biolink:NamedThing	piRNA binding	Binding to a piRNA, a Piwi-associated RNA, a 24- to 30-nucleotide RNA derived from repeat or complex DNA sequence elements and processed by a Dicer-independent mechanism.	tmpzr1t_l9r_go_relaxed.owl	Piwi-associated RNA binding													molecular_function											owl:Class	
GO:0061980	biolink:NamedThing	regulatory RNA binding	Binding to a small regulatory RNA, a short RNA (usually 50-200 nt long) that is either independently transcribed or processed from a longer RNA by an RNAse enzyme.	tmpzr1t_l9r_go_relaxed.owl								dph	2018-02-13T21:46:08Z					molecular_function											owl:Class	
GO:0110103	biolink:NamedThing	RNA polymerase II termination complex	A conserved protein complex capable of 5'-3' exoribonuclease activity. It is able to promote RNA polymerase II (RNAPII) transcription termination by degrading pre-mRNA from the newly formed 5' phosphorylated end.	tmpzr1t_l9r_go_relaxed.owl	TXT complex					In S. cerevisiae, this complex is formed by RAI1 and RAT1; in H. sapiens it is formed by Twi12, Xrn2 and Tan1.		kmv	2018-03-16T18:55:17Z					cellular_component											owl:Class	
GO:0071478	biolink:NamedThing	cellular response to radiation	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electromagnetic radiation stimulus. Electromagnetic radiation is a propagating wave in space with electric and magnetic components. These components oscillate at right angles to each other and to the direction of propagation.	tmpzr1t_l9r_go_relaxed.owl	cellular response to radiation stimulus|cellular response to electromagnetic radiation stimulus					Note that 'radiation' refers to electromagnetic radiation of any wavelength.		mah	2009-12-18T01:59:37Z					biological_process											owl:Class	
GO:0052864	biolink:NamedThing	1-deoxy-D-xylulose 5-phosphate catabolic process	The chemical reactions and pathways resulting in the breakdown of 1-deoxy-D-xylulose 5-phosphate, the 5-phospho derivative of 1-deoxy-D-xylulose. 1-deoxy-D-xylulose 5-phosphate is an intermediate in the non-mevalonate pathway and a common precursor for isoprenoid, thiamin, and pyridoxol biosynthesis.	tmpzr1t_l9r_go_relaxed.owl	(2R,3S)-2,3-dihydroxy-4-oxopentyl dihydrogen phosphate catabolic process|1-deoxy-D-xylulose 5-phosphate degradation|1-deoxy-D-xylulose 5-phosphate catabolism|(2R,3S)-2,3-dihydroxy-4-oxopentyl dihydrogen phosphate catabolism|(2R,3S)-2,3-dihydroxy-4-oxopentyl dihydrogen phosphate breakdown|(2R,3S)-2,3-dihydroxy-4-oxopentyl dihydrogen phosphate degradation|1-deoxy-D-xylulose 5-phosphate breakdown													biological_process											owl:Class	
GO:2000096	biolink:NamedThing	positive regulation of Wnt signaling pathway, planar cell polarity pathway	Any process that activates or increases the frequency, rate or extent of Wnt signaling pathway, planar cell polarity pathway.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of PCP pathway|positive regulation of Wnt receptor signaling pathway, planar cell polarity pathway|positive regulation of Wnt receptor signalling pathway, planar cell polarity pathway|positive regulation of non-canonical Wnt signaling pathway|positive regulation of Wnt-JNK signaling pathway|positive regulation of Wnt-PCP signaling pathway|positive regulation of Wnt-activated signaling pathway, planar cell polarity pathway							jl	2010-09-08T01:07:42Z					biological_process											owl:Class	
GO:0071678	biolink:NamedThing	olfactory bulb axon guidance	The process in which the migration of an axon growth cone of a neuron in the olfactory bulb is directed to its target in the brain in response to a combination of attractive and repulsive cues.	tmpzr1t_l9r_go_relaxed.owl	olfactory bulb axon pathfinding							mah	2010-02-17T02:09:34Z					biological_process											owl:Class	
GO:0047052	biolink:NamedThing	(S)-stylopine synthase activity	Catalysis of the reaction: (S)-cheilanthifoline + [reduced NADPH--hemoprotein reductase] + O2 -> (S)-stylopine + [oxidized NADPH--hemoprotein reductase] + 2 H2O.	tmpzr1t_l9r_go_relaxed.owl	(S)-cheilanthifoline,NADPH:oxygen oxidoreductase (methylenedioxy-bridge-forming)|(S)-cheilanthifoline oxidase (methylenedioxy-bridge-forming) activity	https://github.com/geneontology/go-ontology/issues/21133			EC:1.14.19.64|MetaCyc:1.1.3.32-RXN|RHEA:13773|KEGG_REACTION:R04690									molecular_function											owl:Class	
GO:0097276	biolink:NamedThing	cellular creatinine homeostasis	Any biological process involved in the maintenance of an internal steady state of creatinine at the level of the cell.	tmpzr1t_l9r_go_relaxed.owl								pr	2012-03-22T02:55:46Z					biological_process											owl:Class	
GO:0015870	biolink:NamedThing	acetylcholine transport	The directed movement of acetylcholine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Acetylcholine is an acetic acid ester of the organic base choline and functions as a neurotransmitter, released at the synapses of parasympathetic nerves and at neuromuscular junctions.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0042773	biolink:NamedThing	ATP synthesis coupled electron transport	The transfer of electrons through a series of electron donors and acceptors, generating energy that is ultimately used for synthesis of ATP.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0019034	biolink:NamedThing	viral replication complex	Specific locations and structures in the virus infected cell involved in replicating the viral genome.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0072208	biolink:NamedThing	metanephric smooth muscle tissue development	The process whose specific outcome is the progression of smooth muscle in the metanephros over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-03-18T11:51:59Z					biological_process											owl:Class	
GO:0080129	biolink:NamedThing	proteasome core complex assembly	The aggregation, arrangement and bonding together of a mature, active 20S proteasome core particle complex that does not contain any regulatory particles.	tmpzr1t_l9r_go_relaxed.owl	20S proteasome assembly							dhl	2009-04-29T03:34:50Z					biological_process											owl:Class	
GO:1902269	biolink:NamedThing	positive regulation of polyamine transmembrane transport	Any process that activates or increases the frequency, rate or extent of polyamine transmembrane transport.	tmpzr1t_l9r_go_relaxed.owl	activation of polyamine transmembrane transport|up regulation of polyamine transmembrane transport|upregulation of polyamine transmembrane transport|up-regulation of polyamine transmembrane transport							mcc	2013-06-28T21:34:47Z					biological_process											owl:Class	
GO:0062031	biolink:NamedThing	filamentous growth MAPK cascade	The MAPK cascade which is activated as a result of partial nutrient deprivation and which results in filamentous growth.	tmpzr1t_l9r_go_relaxed.owl								dph	2018-04-17T15:18:44Z					biological_process											owl:Class	
GO:0008145	biolink:NamedThing	phenylalkylamine binding	Binding to phenylalkylamine or one of its derivatives.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0047096	biolink:NamedThing	androst-4-ene-3,17-dione monooxygenase activity	Catalysis of the reaction: AH(2) + androst-4-ene-3,17-dione + O(2) = A + H(2)O + testololactone.	tmpzr1t_l9r_go_relaxed.owl	4-androstene-3,17-dione monooxygenase activity|androstene-3,17-dione hydroxylase activity|androstenedione monooxygenase activity|androst-4-ene-3,17-dione 17-oxidoreductase activity|androst-4-ene-3,17-dione hydroxylase activity|androst-4-ene-3,17-dione-hydrogen-donor:oxygen oxidoreductase (13-hydroxylating, lactonizing)				KEGG_REACTION:R01833|RHEA:22696|EC:1.14.99.12|MetaCyc:1.14.99.12-RXN									molecular_function											owl:Class	
GO:0047444	biolink:NamedThing	N-acylneuraminate-9-phosphate synthase activity	Catalysis of the reaction: H2O + phosphoenolpyruvate + N-acyl-D-mannosamine 6-phosphate = phosphate + N-acylneuraminate 9-phosphate.	tmpzr1t_l9r_go_relaxed.owl	N-acetylneuraminic acid phosphate synthase activity|phosphoenolpyruvate:N-acyl-D-mannosamine-6-phosphate 1-(2-carboxy-2-oxoethyl)transferase activity|N-acylneuraminate-9-phosphate pyruvate-lyase (pyruvate-phosphorylating) activity|N-acetylneuraminate 9-phosphate sialic acid 9-phosphate synthase activity|N-acetylneuraminate 9-phosphate lyase activity|sialic acid 9-phosphate synthetase activity|N-acetylneuraminate 9-phosphate synthetase activity				RHEA:13421|Reactome:R-HSA-4084976|MetaCyc:4.1.3.20-RXN|EC:2.5.1.57							GO:0019007		molecular_function											owl:Class	
GO:0061553	biolink:NamedThing	ganglion maturation	A developmental process, independent of morphogenetic (shape) change, that is required for ganglion to attain its fully functional state.	tmpzr1t_l9r_go_relaxed.owl	ganglia maturation							dph	2013-07-10T08:45:59Z					biological_process											owl:Class	
GO:0008747	biolink:NamedThing	N-acetylneuraminate lyase activity	Catalysis of the reaction: N-acetylneuraminate = N-acetyl-D-mannosamine + pyruvate.	tmpzr1t_l9r_go_relaxed.owl	sialic aldolase activity|acetylneuraminate lyase activity|N-acetylneuraminic lyase activity|N-acetylneuraminic aldolase activity|neuraminic acid aldolase activity|NANA lyase activity|N-acetylneuraminate pyruvate-lyase activity|neuraminate aldolase activity|N-acetylneuraminic acid aldolase activity|N-acetylneuraminic acid lyase activity|NPL|sialic acid aldolase activity|N-acetylneuraminate aldolase activity|N-acetylneuraminate pyruvate-lyase (N-acetyl-D-mannosamine-forming)|acetylneuraminate pyruvate-lyase activity|neuraminic aldolase activity|NALase activity|sialate lyase activity				Reactome:R-HSA-4085217|EC:4.1.3.3|RHEA:23296|MetaCyc:ACNEULY-RXN|KEGG_REACTION:R01811									molecular_function											owl:Class	
GO:0070690	biolink:NamedThing	L-threonine catabolic process to acetyl-CoA	The chemical reactions and pathways resulting in the breakdown of L-threonine (the L-enantiomer of 2-amino-3-hydroxybutyric acid) into glycine and acetaldehyde, with acetaldehyde being subsequently converted to acetyl-CoA.	tmpzr1t_l9r_go_relaxed.owl	L-threonine catabolism to acetyl-CoA|L-threonine degradation to acetyl-CoA|L-threonine breakdown to acetyl-CoA|threonine catabolic process to acetyl-CoA				MetaCyc:PWY-5436			mah	2009-06-03T01:40:22Z					biological_process											owl:Class	
GO:0031372	biolink:NamedThing	UBC13-MMS2 complex	A heterodimeric ubiquitin conjugating enzyme complex that catalyzes assembly of K63-linked polyubiquitin chains, which act as a signal to promote error-free DNA postreplication repair; in Saccharomyces the complex comprises Ubc13p and Mms2p.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0047574	biolink:NamedThing	4-acetamidobutyryl-CoA deacetylase activity	Catalysis of the reaction: 4-acetamidobutanoyl-CoA + H(2)O = 4-aminobutanoyl-CoA + acetate.	tmpzr1t_l9r_go_relaxed.owl	deacetylase-thiolesterase activity|aminobutyryl-CoA thiolesterase activity|4-acetamidobutanoyl-CoA amidohydrolase activity				RHEA:22928|MetaCyc:4-ACETAMIDOBUTYRYL-COA-DEACETYLASE-RXN|KEGG_REACTION:R04056|EC:3.5.1.51									molecular_function											owl:Class	
GO:1900760	biolink:NamedThing	negative regulation of sterigmatocystin biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of sterigmatocystin biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	inhibition of sterigmatocystin biosynthesis|downregulation of sterigmatocystin formation|downregulation of sterigmatocystin biosynthesis|down-regulation of sterigmatocystin synthesis|downregulation of sterigmatocystin biosynthetic process|down-regulation of sterigmatocystin anabolism|negative regulation of sterigmatocystin synthesis|down regulation of sterigmatocystin anabolism|negative regulation of sterigmatocystin biosynthesis|inhibition of sterigmatocystin synthesis|downregulation of sterigmatocystin synthesis|down regulation of sterigmatocystin formation|down regulation of sterigmatocystin biosynthesis|inhibition of sterigmatocystin anabolism|downregulation of sterigmatocystin anabolism|negative regulation of sterigmatocystin anabolism|down-regulation of sterigmatocystin biosynthesis|inhibition of sterigmatocystin formation|down regulation of sterigmatocystin biosynthetic process|inhibition of sterigmatocystin biosynthetic process|down-regulation of sterigmatocystin formation|down regulation of sterigmatocystin synthesis|down-regulation of sterigmatocystin biosynthetic process|negative regulation of sterigmatocystin formation							di	2012-06-04T08:38:30Z					biological_process											owl:Class	
GO:1902704	biolink:NamedThing	hexose catabolic process to acetone	The chemical reactions and pathways resulting in the breakdown of hexose to acetone.	tmpzr1t_l9r_go_relaxed.owl	solventogenesis|hexose breakdown to acetone|hexose catabolic process to 2-propanone|hexose catabolism to acetone|hexose degradation to acetone							tb	2014-02-19T18:43:13Z			GO:1990285		biological_process											owl:Class	
GO:0021514	biolink:NamedThing	ventral spinal cord interneuron differentiation	The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of ventral spinal cord interneurons. Ventral spinal cord interneurons are cells located in the ventral portion of the spinal cord that transmit signals between sensory and motor neurons and are required for reflexive responses. Differentiation includes the processes involved in commitment of a cell to a specific fate.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0102484	biolink:NamedThing	esculetin glucosyltransferase activity	Catalysis of the reaction: esculetin + UDP-alpha-D-glucose(2-) <=> esculin + UDP(3-) + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-14182									molecular_function											owl:Class	
GO:0008818	biolink:NamedThing	cobalamin 5'-phosphate synthase activity	Catalysis of the reaction: adenosylcobinamide-GDP + alpha-ribazole-5'-phosphate = adenosylcobalamin-5'-phosphate + GMP.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:COBALAMIN5PSYN-RXN|RHEA:23560									molecular_function											owl:Class	
GO:0047014	biolink:NamedThing	glycerol-3-phosphate 1-dehydrogenase [NADP+] activity	Catalysis of the reaction: sn-glycerol 3-phosphate + NADP(+) = D-glyceraldehyde 3-phosphate + H(+) + NADPH.	tmpzr1t_l9r_go_relaxed.owl	sn-glycerol-3-phosphate:NADP+ 1-oxidoreductase activity|glycerin-3-phosphate dehydrogenase activity|NADPH-dependent glycerin-3-phosphate dehydrogenase activity|L-glycerol 3-phosphate:NADP oxidoreductase activity|glycerol phosphate (nicotinamide adenine dinucleotide phosphate) dehydrogenase activity				RHEA:19773|EC:1.1.1.177|KEGG_REACTION:R00845|MetaCyc:1.1.1.177-RXN									molecular_function											owl:Class	
GO:0005988	biolink:NamedThing	lactose metabolic process	The chemical reactions and pathways involving lactose, the disaccharide galactopyranosyl-glucose.	tmpzr1t_l9r_go_relaxed.owl	lactose metabolism													biological_process											owl:Class	
GO:0008866	biolink:NamedThing	fructuronate reductase activity	Catalysis of the reaction: D-mannonate + NAD(+) = D-fructuronate + H(+) + NADH.	tmpzr1t_l9r_go_relaxed.owl	D-mannonate:NAD oxidoreductase activity|mannonic dehydrogenase activity|mannonate oxidoreductase activity|D-mannonate dehydrogenase activity|D-mannonate:NAD+ 5-oxidoreductase activity|D-mannonate oxidoreductase activity				RHEA:15729|MetaCyc:MANNONOXIDOREDUCT-RXN|KEGG_REACTION:R02454|EC:1.1.1.57									molecular_function											owl:Class	
GO:0047324	biolink:NamedThing	phosphoenolpyruvate-glycerone phosphotransferase activity	Catalysis of the reaction: glycerone + phosphoenolpyruvate = glycerone phosphate + pyruvate.	tmpzr1t_l9r_go_relaxed.owl	phosphoenolpyruvate:glycerone phosphotransferase activity				EC:2.7.1.121|KEGG_REACTION:R01012|RHEA:18381|MetaCyc:2.7.1.121-RXN									molecular_function											owl:Class	
GO:1901125	biolink:NamedThing	candicidin metabolic process	The chemical reactions and pathways involving candicidin.	tmpzr1t_l9r_go_relaxed.owl	candicidin metabolism							yaf	2012-07-11T03:16:32Z					biological_process											owl:Class	
GO:0042370	biolink:NamedThing	thiamine diphosphate dephosphorylation	The removal of one or more phosphate groups from thiamine diphosphate, a derivative of thiamine (vitamin B1) which acts as a coenzyme in a range of processes including the Krebs cycle.	tmpzr1t_l9r_go_relaxed.owl	TPP dephosphorylation|thiamin diphosphate dephosphorylation													biological_process											owl:Class	
GO:0071858	biolink:NamedThing	corazonin receptor binding	Binding to a corazonin receptor.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-09-10T03:23:40Z					molecular_function											owl:Class	
GO:0002401	biolink:NamedThing	tolerance induction in mucosal-associated lymphoid tissue	Tolerance induction taking place in the mucosal-associated lymphoid tissue (MALT).	tmpzr1t_l9r_go_relaxed.owl	tolerance induction in MALT													biological_process											owl:Class	
GO:1990659	biolink:NamedThing	sequestering of manganese ion	The process of binding or confining manganese ions such that they are separated from other components of a biological system.	tmpzr1t_l9r_go_relaxed.owl	manganese ion storage|storage of manganese ion|retention of manganese ion|manganese ion sequestration|manganese ion sequestering|manganese ion retention|sequestration of manganese ion					An example of this is S100A9 in human (UniProt symbol P06702) in PMID:25417112 (inferred from direct assay).		bhm	2015-02-25T11:41:12Z					biological_process											owl:Class	
GO:0034376	biolink:NamedThing	conversion of discoidal high-density lipoprotein particle to spherical high-density lipoprotein particle	The process in which a discoidal high-density lipoprotein (HDL) particle acquires additional lipid or protein molecules, and cholesterol in the particle is converted to tightly bound cholesterol esters by the action of phosphatidylcholine-sterol O-acyltransferase (lecithin cholesterol acyltransferase; LCAT), resulting in the formation of a spherical HDL particle.	tmpzr1t_l9r_go_relaxed.owl	conversion of discoidal HDL to spherical HDL|discoidal HDL remodeling|discoidal high-density lipoprotein remodeling													biological_process											owl:Class	
GO:0036116	biolink:NamedThing	long-chain fatty-acyl-CoA catabolic process	The chemical reactions and pathways resulting in the breakdown of long-chain fatty-acyl-CoAs, any derivative of coenzyme A in which the sulfhydryl group is in a thioester linkage with a medium-chain fatty-acyl group. A long-chain fatty acid is a fatty acid with a chain length between C13 and C22.	tmpzr1t_l9r_go_relaxed.owl	long-chain fatty-acyl-CoA degradation|long-chain fatty-acyl-CoA breakdown|long-chain fatty-acyl-CoA catabolism							bf	2012-02-15T11:30:24Z					biological_process											owl:Class	
GO:1905509	biolink:NamedThing	protein localization to interphase microtubule organizing center	A process in which a protein is transported to, or maintained in, a location within an interphase microtubule organizing center.	tmpzr1t_l9r_go_relaxed.owl	protein localisation to interphase microtubule organizing center|protein localisation in interphase microtubule organizing center|protein localization in interphase microtubule organizing center							mah	2016-09-28T12:32:24Z					biological_process											owl:Class	
GO:0004733	biolink:NamedThing	pyridoxamine-phosphate oxidase activity	Catalysis of the reaction: pyridoxamine 5'-phosphate + H2O + O2 = pyridoxal 5'-phosphate + NH3 + hydrogen peroxide.	tmpzr1t_l9r_go_relaxed.owl	pyridoxine (pyridoxamine)phosphate oxidase activity|pyridoxamine phosphate oxidase activity|pyridoxine (pyridoxamine) 5'-phosphate oxidase activity|pyridoxal 5'-phosphate synthase activity|PMP oxidase activity|PdxH|pyridoxaminephosphate oxidase deaminating|pyridoxamine 5'-phosphate oxidase activity|pyridoxamine-5'-phosphate:oxygen oxidoreductase (deaminating)|pyridoxol-5'-phosphate:oxygen oxidoreductase (deaminating)				MetaCyc:PMPOXI-RXN|EC:1.4.3.5|RHEA:15817|Reactome:R-HSA-965019|Reactome:R-HSA-965079									molecular_function											owl:Class	
GO:0071641	biolink:NamedThing	negative regulation of macrophage inflammatory protein 1 alpha production	Any process that stops, prevents, or reduces the frequency, rate, or extent of production of macrophage inflammatory protein 1 alpha.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of CCL3 production|negative regulation of MIP-1a production|negative regulation of macrophage inflammatory protein production|negative regulation of chemokine (C-C motif) ligand 3 production							mah	2010-02-12T10:39:51Z					biological_process											owl:Class	
GO:0047102	biolink:NamedThing	aminomuconate-semialdehyde dehydrogenase activity	Catalysis of the reaction: H2O + NAD+ + 2-aminomuconate semialdehyde = NADH + 2-amino-muconate.	tmpzr1t_l9r_go_relaxed.owl	2-aminomuconate-6-semialdehyde:NAD+ 6-oxidoreductase activity|2-hydroxymuconic semialdehyde dehydrogenase activity|2-hydroxymuconic acid semialdehyde dehydrogenase activity|alpha-aminomuconic epsilon-semialdehyde dehydrogenase activity|2-aminomuconate semialdehyde dehydrogenase activity|2-hydroxymuconate semialdehyde dehydrogenase activity|alpha-hydroxymuconic epsilon-semialdehyde dehydrogenase activity				Reactome:R-HSA-71239|MetaCyc:1.2.1.32-RXN|RHEA:14469|EC:1.2.1.32|UM-BBD_reactionID:r1434									molecular_function											owl:Class	
GO:0062226	biolink:NamedThing	regulation of adult somatic muscle development	Any process that modulates the rate, frequency or extent of adult somatic muscle development.	tmpzr1t_l9r_go_relaxed.owl								dph	2020-03-16T13:24:07Z					biological_process											owl:Class	
GO:0036047	biolink:NamedThing	peptidyl-lysine demalonylation	The process of removing a malonyl group (CO-CH2-CO) from an malonylated lysine residue in a peptide or protein.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-12-12T09:39:17Z					biological_process											owl:Class	
GO:0099138	biolink:NamedThing	altruistic, chimeric sorocarp development	Development of a chimeric sorocarp in which cells of all genotypes have an equal chance of becoming a spore cell.	tmpzr1t_l9r_go_relaxed.owl	fully co-operative, chimeric sorocarp development													biological_process											owl:Class	
GO:0031673	biolink:NamedThing	H zone	A relatively pale zone traversing the center of the A band of a sarcomere, visible in relaxed muscle fibers; consists of the central portion of thick (myosin) filaments that are not overlapped by thin (actin) filaments.	tmpzr1t_l9r_go_relaxed.owl	H disc|H band				Wikipedia:Sarcomere#bands									cellular_component											owl:Class	
GO:0071483	biolink:NamedThing	cellular response to blue light	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a blue light stimulus. Blue light is electromagnetic radiation with a wavelength of between 440 and 500nm.	tmpzr1t_l9r_go_relaxed.owl	cellular response to blue light stimulus							mah	2009-12-18T02:09:48Z					biological_process											owl:Class	
GO:0034612	biolink:NamedThing	response to tumor necrosis factor	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tumor necrosis factor stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to TNF													biological_process											owl:Class	
GO:1990646	biolink:NamedThing	cellular response to prolactin	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prolactin stimulus.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-02-18T16:53:11Z					biological_process											owl:Class	
GO:1990637	biolink:NamedThing	response to prolactin	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prolactin stimulus. The anterior pituitary hormone prolactin has a number of roles including being essential for lactation.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-02-10T23:47:11Z					biological_process											owl:Class	
GO:0102407	biolink:NamedThing	sn-2-glycerol-3-phosphate C22:0-DCA-CoA acyl transferase activity	Catalysis of the reaction: C22:0-DCA-CoA + sn-glycerol 3-phosphate <=> coenzyme A + 2-C22:0-DCA-LPA.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-13734									molecular_function											owl:Class	
GO:0008745	biolink:NamedThing	N-acetylmuramoyl-L-alanine amidase activity	Catalysis of the hydrolysis of the link between N-acetylmuramoyl residues and L-amino acid residues in certain bacterial cell-wall glycopeptides.	tmpzr1t_l9r_go_relaxed.owl	acetylmuramoyl-alanine amidase activity|N-acetylmuramylalanine amidase activity|N-acetylmuramic acid L-alanine amidase activity|N-acylmuramyl-L-alanine amidase activity|N-acetylmuramyl-L-alanine amidase activity|acetylmuramyl-L-alanine amidase activity|N-acetylmuramoyl-L-alanine amidase type II|acetylmuramyl-alanine amidase activity|N-acetylmuramoyl-L-alanine amidase type I				MetaCyc:3.5.1.28-RXN|Reactome:R-HSA-6799977|EC:3.5.1.28									molecular_function											owl:Class	
GO:0030723	biolink:NamedThing	ovarian fusome organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the fusome of ovarian cells, an organelle derived from the spectrosome. It anchors the mitotic spindle pole to provide orientation during cystoblast cell divisions.	tmpzr1t_l9r_go_relaxed.owl	ovarian fusome organisation|ovarian fusome organization and biogenesis													biological_process											owl:Class	
GO:0051699	biolink:NamedThing	proline oxidase activity	Catalysis of the reaction: L-proline + O2 + H2O = L-delta1-pyrroline-5-carboxylate + H2O2.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-821|RHEA:26124									molecular_function											owl:Class	
GO:0035180	biolink:NamedThing	larval wandering behavior	The movement of a third instar larva through a substrate in search of a pupation site. This movement occurs without feeding and is characterized by short bursts of forward movement, separated by stops and repeated side-to-side head probes, followed normally by a change in direction.	tmpzr1t_l9r_go_relaxed.owl	larval wandering behaviour													biological_process											owl:Class	
GO:0019547	biolink:NamedThing	arginine catabolic process to ornithine	The chemical reactions and pathways resulting in the breakdown of arginine into other compounds, including ornithine.	tmpzr1t_l9r_go_relaxed.owl	arginine degradation to ornithine|arginine breakdown to ornithine													biological_process											owl:Class	
GO:0097226	biolink:NamedThing	sperm mitochondrial sheath	The tightly packed helical sheath of ATP-producing mitochondria restricted to the midpiece of the sperm flagellum.	tmpzr1t_l9r_go_relaxed.owl								pr	2012-01-25T01:25:08Z					cellular_component											owl:Class	
GO:0097658	biolink:NamedThing	Asi complex	A nuclear ubiquitin ligase multiprotein complex located in the inner nuclear membrane (INM) that recognizes and ubiquitinates misfolded INM proteins and also some proteins involved in sterol biosynthesis, during ER-associated protein degradation (ERAD). In S. cerevisiae, this complex contains the ubiquitin ligases Asi1p and Asi3p.	tmpzr1t_l9r_go_relaxed.owl								pr	2014-09-29T15:08:29Z					cellular_component											owl:Class	
GO:2001013	biolink:NamedThing	epithelial cell proliferation involved in renal tubule morphogenesis	Any epithelial cell proliferation that is involved in renal tubule morphogenesis.	tmpzr1t_l9r_go_relaxed.owl								yaf	2011-08-12T11:37:29Z					biological_process											owl:Class	
GO:0000341	biolink:NamedThing	RNA trimethylguanosine cap binding	Binding to the trimethylguanosine (m(3)(2,2,7)-GTP) group located at the 5' end of some RNA molecules. Such trimethylated cap structures, generally produced by posttranscriptional modification of a 7-methylguanosine cap, are often found on snRNAs and snoRNAs transcribed by RNA polymerase II, but have also be found on snRNAs transcribed by RNA polymerase III. They have also been found on a subset of the mRNA population in some species, e.g. C. elegans.	tmpzr1t_l9r_go_relaxed.owl	RNA m2,2,7G cap binding													molecular_function											owl:Class	
GO:0051036	biolink:NamedThing	regulation of endosome size	Any process that modulates the volume of an endosome, a membrane-bounded organelle that carries materials newly ingested by endocytosis.	tmpzr1t_l9r_go_relaxed.owl	endosome enlargement													biological_process											owl:Class	
GO:0060365	biolink:NamedThing	coronal suture morphogenesis	The process in which the coronal suture is generated and organized.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0035928	biolink:NamedThing	rRNA import into mitochondrion	The process in which a rRNA, ribosomal ribonucleic acid, transported from the cytosol into the mitochondrial matrix.	tmpzr1t_l9r_go_relaxed.owl	cytoplasmic rRNA import into mitochondrion|nuclear-encoded rRNA import into mitochondrion							bf	2011-07-19T09:41:42Z					biological_process											owl:Class	
GO:0120285	biolink:NamedThing	tyrosine sensor activity	Binding to and responding, e.g. by conformational change, to changes in the cellular level of tyrosine.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/20181						krc	2020-11-18T01:19:42Z					molecular_function											owl:Class	
GO:0046054	biolink:NamedThing	dGMP metabolic process	The chemical reactions and pathways involving dGMP, deoxyguanosine monophosphate (2'-deoxyguanosine 5'-phosphate).	tmpzr1t_l9r_go_relaxed.owl	dGMP metabolism													biological_process											owl:Class	
GO:0039651	biolink:NamedThing	induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process	Any process in which a virus increases the frequency, rate or extent of host cysteine-type endopeptidase activity (also called caspase activity) which contributes to the apoptotic process.	tmpzr1t_l9r_go_relaxed.owl	induction by virus of host caspase activity|activation of host caspases by virus							bf	2012-10-09T15:44:29Z					biological_process											owl:Class	
GO:0033887	biolink:NamedThing	chondro-4-sulfatase activity	Catalysis of the reaction: 4-deoxy-beta-D-gluc-4-enuronosyl-(1->3)-N-acetyl-D-galactosamine 4-sulfate + H(2)O = 4-deoxy-beta-D-gluc-4-enuronosyl-(1->3)-N-acetyl-D-galactosamine + H(+) + sulfate.	tmpzr1t_l9r_go_relaxed.owl	4-deoxy-beta-D-gluc-4-enuronosyl-(1,3)-N-acetyl-D-galactosamine-4-sulfate 4-sulfohydrolase activity				RHEA:11444|MetaCyc:CHONDRO-4-SULFATASE-RXN|EC:3.1.6.9|KEGG_REACTION:R03517									molecular_function											owl:Class	
GO:0060545	biolink:NamedThing	positive regulation of necroptotic process	Any process that increases the rate, frequency or extent of a necroptotic process, a necrotic cell death process that results from the activation of endogenous cellular processes, such as signaling involving death domain receptors or Toll-like receptors.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of necroptosis							dph	2009-04-13T01:47:27Z					biological_process											owl:Class	
GO:0060544	biolink:NamedThing	regulation of necroptotic process	Any process that modulates the rate, frequency or extent of a necroptotic process, a necrotic cell death process that results from the activation of endogenous cellular processes, such as signaling involving death domain receptors or Toll-like receptors.	tmpzr1t_l9r_go_relaxed.owl	regulation of necroptosis							dph	2009-04-13T01:43:22Z					biological_process											owl:Class	
GO:0120187	biolink:NamedThing	positive regulation of protein localization to chromatin	Any process that activates or increases the frequency, rate or extent of protein localization to chromatin.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of protein localisation to chromatin							krc	2018-07-14T00:21:28Z					biological_process											owl:Class	
GO:1901709	biolink:NamedThing	(+)-larreatricin metabolic process	The chemical reactions and pathways involving (+)-larreatricin.	tmpzr1t_l9r_go_relaxed.owl	(+)-larreatricin metabolism							ms	2012-12-19T14:44:29Z					biological_process											owl:Class	
GO:0072517	biolink:NamedThing	host cell viral assembly compartment	A membrane-bounded compartment that forms in the cytoplasm of the host cell, in which virus assembly takes place.	tmpzr1t_l9r_go_relaxed.owl	host cell viral assembly site|viral assembly site|virion assembly compartment|viral assembly compartment|host cell virion assembly compartment							mah	2010-12-21T03:08:42Z			GO:0072516		cellular_component											owl:Class	
GO:0080081	biolink:NamedThing	4-methylumbelliferyl-beta-D-glucopyranoside beta-glucosidase activity	Catalysis of the hydrolysis of glucosidic link in 4-methylumbelliferyl-beta-D-glucopyranoside.	tmpzr1t_l9r_go_relaxed.owl								dhl	2009-04-14T04:09:06Z					molecular_function											owl:Class	
GO:1905499	biolink:NamedThing	trichome papilla formation	The aggregation, arrangement and bonding together of a set of components to form a trichome papilla.	tmpzr1t_l9r_go_relaxed.owl	trichome papilla assembly							tb	2016-09-27T00:28:06Z					biological_process											owl:Class	
GO:1902014	biolink:NamedThing	poly(glycerol phosphate) teichoic acid biosynthetic process	The chemical reactions and pathways resulting in the formation of poly(glycerol phosphate) teichoic acid.	tmpzr1t_l9r_go_relaxed.owl	poly(glycerol phosphate) teichoic acid formation|poly(glycerol phosphate) teichoic acid biosynthesis|poly(glycerol phosphate) teichoic acid anabolism|poly(glycerol phosphate) teichoic acid synthesis							tb	2013-03-22T15:43:50Z					biological_process											owl:Class	
GO:0047022	biolink:NamedThing	7-beta-hydroxysteroid dehydrogenase (NADP+) activity	Catalysis of the reaction: NADP+ + a 7-beta-hydroxysteroid = NADPH + H+ + a 7-oxosteroid.	tmpzr1t_l9r_go_relaxed.owl	7beta-hydroxysteroid:NADP+ 7-oxidoreductase activity|NADP-dependent 7-beta-hydroxysteroid dehydrogenase activity|NADP-dependent 7beta-hydroxysteroid dehydrogenase activity|7beta-hydroxysteroid dehydrogenase (NADP+)				MetaCyc:1.1.1.201-RXN|Wikipedia:7beta-hydroxysteroid_dehydrogenase_(NADP+)|EC:1.1.1.201|RHEA:20233									molecular_function											owl:Class	
GO:0000810	biolink:NamedThing	diacylglycerol diphosphate phosphatase activity	Catalysis of the reaction: a 1,2-diacyl-sn-glycerol 3-diphosphate + H2O = a 1,2-diacyl-sn-glycerol 3-phosphate + phosphate.	tmpzr1t_l9r_go_relaxed.owl	DGPP phosphatase activity|diacylglycerol pyrophosphate phosphatase activity|DGPP phosphohydrolase activity				RHEA:27449|EC:3.1.3.81|MetaCyc:RXN-11277									molecular_function											owl:Class	
GO:1905838	biolink:NamedThing	regulation of telomeric D-loop disassembly	Any process that modulates the frequency, rate or extent of telomeric D-loop disassembly.	tmpzr1t_l9r_go_relaxed.owl								nc	2017-01-18T11:01:38Z					biological_process											owl:Class	
GO:0021654	biolink:NamedThing	rhombomere boundary formation	The process that gives rise to a rhombomere boundary. This process pertains to the initial formation of a boundary delimiting a rhombomere. Rhombomeres are transverse segments of the developing rhombencephalon that are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0035778	biolink:NamedThing	pronephric nephron tubule epithelial cell differentiation	The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the pronephric nephron tubule as it progresses from its formation to the mature state.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-04-04T11:07:47Z					biological_process											owl:Class	
GO:0047160	biolink:NamedThing	alkylglycerophosphate 2-O-acetyltransferase activity	Catalysis of the reaction: 1-alkyl-sn-glycerol 3-phosphate + acetyl-CoA = 1-alkyl-2-acetyl-sn-glycerol 3-phosphate + CoA.	tmpzr1t_l9r_go_relaxed.owl	acetyl-CoA:1-alkyl-sn-glycero-3-phosphate 2-O-acetyltransferase activity|alkyllyso-GP:acetyl-CoA acetyltransferase activity				RHEA:18557|KEGG_REACTION:R03455|MetaCyc:2.3.1.105-RXN|EC:2.3.1.105									molecular_function											owl:Class	
GO:1990305	biolink:NamedThing	RAD6-UBR2 ubiquitin ligase complex	A ubiquitin ligase complex consisting of RAD6 and UBR2 components. It may act in a quality control pathway for proteins synthesized on cytosolic ribosomes. The UBR2 component lacks sequence motifs required for N-end rule degradation.	tmpzr1t_l9r_go_relaxed.owl	RAD6-UBR2 complex					This complex has been identified in Saccharomyces cerevisiae (P19812) - see PMID:15504724		bhm	2014-03-03T22:14:32Z					cellular_component											owl:Class	
GO:0021989	biolink:NamedThing	olfactory cortex development	The progression of the olfactory cortex over time from its initial formation until its mature state. The olfactory cortex is involved in the perception of smell. It receives input from the olfactory bulb and is responsible for the identification of odors.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0046025	biolink:NamedThing	precorrin-6Y C5,15-methyltransferase (decarboxylating) activity	Catalysis of the reaction: 2 S-adenosyl-L-methionine + precorrin-6Y = 2 S-adenosyl-L-homocysteine + precorrin-8X + CO2.	tmpzr1t_l9r_go_relaxed.owl	S-adenosyl-L-methionine:1-precorrin-6Y C5,15-methyltransferase (C-12-decarboxylating)|precorrin-6 methyltransferase activity|precorrin-6Y methylase activity				EC:2.1.1.132|MetaCyc:2.1.1.132-RXN|RHEA:17477									molecular_function											owl:Class	
GO:0017118	biolink:NamedThing	lipoyltransferase activity	Catalysis of the transfer of the lipoyl group from lipoyl-AMP to the lysine residue of lipoate-dependent enzyme.	tmpzr1t_l9r_go_relaxed.owl					RHEA:20473									molecular_function											owl:Class	
GO:0009327	biolink:NamedThing	NAD(P)+ transhydrogenase complex (AB-specific)	A protein complex that possesses NAD(P)+ transhydrogenase (AB-specific) activity. Homodimeric, trimeric, and heterotetrameric complexes have been identified.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0044295	biolink:NamedThing	axonal growth cone	The migrating motile tip of a growing nerve cell axon.	tmpzr1t_l9r_go_relaxed.owl	axon growth cone				NIF_Subcellular:sao203987954|NIF_Subcellular:sao1594955670			jl	2010-02-04T03:57:16Z					cellular_component											owl:Class	
GO:0006405	biolink:NamedThing	RNA export from nucleus	The directed movement of RNA from the nucleus to the cytoplasm.	tmpzr1t_l9r_go_relaxed.owl	RNA export from cell nucleus|RNA-nucleus export|RNA transport from nucleus to cytoplasm|RNA export out of nucleus													biological_process											owl:Class	
GO:0070392	biolink:NamedThing	detection of lipoteichoic acid	The series of events in which a lipoteichoic acid stimulus is received by a cell and converted into a molecular signal; lipoteichoic acid is a major component of the cell wall of gram-positive bacteria and typically consists of a chain of glycerol-phosphate repeating units linked to a glycolipid anchor.	tmpzr1t_l9r_go_relaxed.owl	detection of LTA													biological_process											owl:Class	
GO:0032418	biolink:NamedThing	lysosome localization	Any process in which a lysosome is transported to, and/or maintained in, a specific location.	tmpzr1t_l9r_go_relaxed.owl	lysosome localisation													biological_process											owl:Class	
GO:0034583	biolink:NamedThing	21U-RNA binding	Binding to a 21U-RNA, a 21-nucleotide RNA characterized by a uridine 5'-monophosphate and a modified 3' end resistant to periodate degradation. 21U-RNAs are derived from distinct, autonomously expressed loci within the genome.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1900598	biolink:NamedThing	demethylkotanin catabolic process	The chemical reactions and pathways resulting in the breakdown of demethylkotanin.	tmpzr1t_l9r_go_relaxed.owl	demethylkotanin breakdown|demethylkotanin degradation|demethylkotanin catabolism							di	2012-05-15T06:55:14Z					biological_process											owl:Class	
GO:1900357	biolink:NamedThing	regulation of nigerotriose transport	Any process that modulates the frequency, rate or extent of nigerotriose transport.	tmpzr1t_l9r_go_relaxed.owl								tt	2012-04-06T02:18:06Z					biological_process											owl:Class	
GO:0002394	biolink:NamedThing	tolerance induction in gut-associated lymphoid tissue	Tolerance induction taking place in the gut-associated lymphoid tissue (GALT).	tmpzr1t_l9r_go_relaxed.owl	tolerance induction in GALT|oral tolerance													biological_process											owl:Class	
GO:0046753	biolink:NamedThing	non-lytic viral release	The exit of a viral particle from a cell that does not involve cell lysis.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/18852												biological_process											owl:Class	
GO:0060924	biolink:NamedThing	atrial cardiac muscle cell fate commitment	The commitment of cells to atrial cardiac muscle cell fates and their capacity to differentiate into cardiac muscle cells of the atrium. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction.	tmpzr1t_l9r_go_relaxed.owl	atrial cardiomyocyte cell fate commitment|atrial heart muscle cell fate commitment							dph	2009-09-29T11:46:10Z					biological_process											owl:Class	
GO:0019250	biolink:NamedThing	aerobic cobalamin biosynthetic process	The chemical reactions and pathways resulting in the formation of cobalamin (vitamin B12) in the presence of oxygen.	tmpzr1t_l9r_go_relaxed.owl	aerobic cobalamin formation|vitamin B12 biosynthesis, aerobic|aerobic vitamin B12 biosynthetic process|vitamin B12 biosynthetic process, aerobic|aerobic cobalamin biosynthesis|cobalamin biosynthesis, aerobic|aerobic cobalamin anabolism|aerobic cobalamin synthesis|cobalamin biosynthetic process, aerobic|aerobic vitamin B12 biosynthesis				MetaCyc:P381-PWY									biological_process											owl:Class	
GO:0033808	biolink:NamedThing	6'-deoxychalcone synthase activity	Catalysis of the reaction: 3 malonyl-CoA + 4-coumaroyl-CoA + NADPH + H+ = 4 CoA + isoliquiritigenin + 3 CO2 + NADP+ + H2O.	tmpzr1t_l9r_go_relaxed.owl	malonyl-CoA:4-coumaroyl-CoA malonyltransferase (cyclizing, reducing) activity				RHEA:10584|EC:2.3.1.170|MetaCyc:RXN-3142									molecular_function											owl:Class	
GO:0060214	biolink:NamedThing	endocardium formation	Formation of the endocardium of the heart. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0015898	biolink:NamedThing	amiloride transport	The directed movement amiloride into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Amiloride is a potent and specific inhibitor of sodium ion entry into cells. It is used as a potassium-sparing diuretic.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0097338	biolink:NamedThing	response to clozapine	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a clozapine stimulus.	tmpzr1t_l9r_go_relaxed.owl								pr	2012-06-12T11:07:01Z					biological_process											owl:Class	
GO:0034425	biolink:NamedThing	etioplast envelope	The double lipid bilayer enclosing the etioplast and separating its contents from the rest of the cytoplasm; includes the intermembrane space.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0033290	biolink:NamedThing	eukaryotic 48S preinitiation complex	A protein complex composed of the small ribosomal subunit, eIF3, eIF1A, methionyl-initiatior methionine and a capped mRNA. The complex is initially positioned at the 5'-end of the capped mRNA.	tmpzr1t_l9r_go_relaxed.owl	eukaryotic 48S initiation complex|eukaryotic 48S pre-initiation complex											GO:0016283		cellular_component											owl:Class	
GO:0102960	biolink:NamedThing	momilactone-A synthase activity	Catalysis of the reaction: 3beta-hydroxy-9beta-pimara-7,15-diene-19,6beta-olide + NAD(P) = momilactone A + H+ + NAD(P)H.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-9290|RHEA:25367|EC:1.1.1.295									molecular_function											owl:Class	
GO:0047191	biolink:NamedThing	1-alkylglycerophosphocholine O-acyltransferase activity	Catalysis of the reaction: 1-alkyl-sn-glycero-3-phosphocholine + acyl-CoA = 1-alkyl-2-acyl-sn-glycero-3-phosphocholine + CoA.	tmpzr1t_l9r_go_relaxed.owl	acyl-CoA:1-alkyl-sn-glycero-3-phosphocholine O-acyltransferase activity				RHEA:23992|EC:2.3.1.63|MetaCyc:2.3.1.63-RXN									molecular_function											owl:Class	
GO:1901704	biolink:NamedThing	L-glutamine biosynthetic process	The chemical reactions and pathways resulting in the formation of L-glutamine.	tmpzr1t_l9r_go_relaxed.owl	L-glutamine biosynthesis|L-glutamine synthesis|L-glutamine anabolism|L-glutamine formation							pde	2012-12-13T23:32:52Z					biological_process											owl:Class	
GO:0110064	biolink:NamedThing	lncRNA catabolic process	The chemical reactions and pathways resulting in the breakdown of lncRNAs, non-coding RNAs over 200 nucleotides in length.	tmpzr1t_l9r_go_relaxed.owl	lncRNA breakdown|lncRNA catabolism|lncRNA degradation							kmv	2017-11-06T13:49:49Z					biological_process											owl:Class	
GO:0072588	biolink:NamedThing	box H/ACA RNP complex	A ribonucleoprotein complex that contains an RNA of the box H/ACA type and the four core proteins dyskerin, NOP10, NHP2, and GAR1 (human protein nomenclature). RNA pseudouridylation (isomerization of uridine to pseudouridine) is the major, and most likely the ancestral, function of H/ACA RNPs. Pseudouridylation targets include both large and small ribosomal RNAs (rRNAs), and small nuclear RNA (U2 snRNA). In addition to these catalytic H/ACA RNPs, a less abundant but more diverse class of structural H/ACA RNPs exists, which does not have pseudouridylation activity. These include the vertebrate telomerase RNP complex.	tmpzr1t_l9r_go_relaxed.owl	sRNP complex|box H/ACA snoRNP pseudouridylase complex	https://github.com/geneontology/go-ontology/issues/20416						mah	2011-02-10T01:43:37Z					cellular_component											owl:Class	
GO:0120204	biolink:NamedThing	methylcytosine to 5-glyceryl-methylcytosine dioxygenase activity	Catalysis of the reaction: methylcytosine + L-ascorbate + O2 = 5-glyceryl-methylcytosine + glyoxylate + CO2.	tmpzr1t_l9r_go_relaxed.owl								krc	2019-05-10T15:58:47Z					molecular_function											owl:Class	
GO:0070850	biolink:NamedThing	TACC/TOG complex	A protein complex that contains the transforming acidic coiled coil (TACC) protein and the TOG protein (Mia1p/Alp7p and Alp14, respectively, in fission yeast), and is involved in microtubule array remodeling as cells progress through the cell cycle. The TACC/TOG complex is conserved in eukaryotes, associates with microtubules, and shuttles between the nucleus and the cytoplasm during interphase.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-08-05T03:06:08Z					cellular_component											owl:Class	
GO:0034512	biolink:NamedThing	box C/D RNA binding	Binding to a box C/D small nucleolar RNA.	tmpzr1t_l9r_go_relaxed.owl	box C/D sRNA binding|box C/D snoRNA binding	https://github.com/geneontology/go-ontology/issues/20416												molecular_function											owl:Class	
GO:0102248	biolink:NamedThing	diacylglycerol transacylase activity	Catalysis of the reaction: 2 a 1,2-diacyl-sn-glycerol = a triacyl-sn-glycerol + a 2-monoglyceride.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-12383									molecular_function											owl:Class	
GO:0004589	biolink:NamedThing	orotate reductase (NADH) activity	Catalysis of the reaction: (S)-dihydroorotate + NAD(+) = H(+) + NADH + orotate.	tmpzr1t_l9r_go_relaxed.owl	(S)-dihydroorotate:NAD+ oxidoreductase activity				KEGG_REACTION:R01869|MetaCyc:OROTATE-REDUCTASE-NADH-RXN|EC:1.3.1.14|RHEA:13513									molecular_function											owl:Class	
GO:0039576	biolink:NamedThing	suppression by virus of host JAK-STAT cascade via inhibition of JAK1 activity	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of a JAK-STAT signal cascade in a host organism by reducing the activity of host JAK1 (Janus Kinase 1).	tmpzr1t_l9r_go_relaxed.owl	suppression by virus of host janus kinase 1 activity|inhibition of host JAK activity by virus|suppression by virus of tyrosine phosphorylation of host STAT protein|negative regulation by virus of tyrosine phosphorylation of host STAT protein|negative regulation by virus of host JAK|viral inhibition of tyrosine phosphorylation of host STAT protein|suppression by virus of host JAK1 activity	https://github.com/geneontology/go-ontology/issues/21963			VZ:784			bf				GO:0039515		biological_process											owl:Class	
GO:0045793	biolink:NamedThing	positive regulation of cell size	Any process that increases cell size.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of cell size|up regulation of cell size|activation of cell size|upregulation of cell size|stimulation of cell size													biological_process											owl:Class	
GO:0052801	biolink:NamedThing	bicyclic nitroimidazole metabolic process	The chemical reactions and pathways involving bicyclic nitroimidazoles, imidazole derivatives with two rings and a nitro group attached to one ring.	tmpzr1t_l9r_go_relaxed.owl	bicyclic nitroimidazole metabolism													biological_process											owl:Class	
GO:0055054	biolink:NamedThing	fructose:proton symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: fructose + H+ = fructose + H+.	tmpzr1t_l9r_go_relaxed.owl	fructose:hydrogen symporter activity													molecular_function											owl:Class	
GO:0010426	biolink:NamedThing	DNA methylation on cytosine within a CHH sequence	The covalent transfer of a methyl group, to C-5 or N-4, of a cytosine located within an asymmetric CHH sequence in a DNA molecule. H stands for an adenine, cytosine, or thymine nucleotide.	tmpzr1t_l9r_go_relaxed.owl	cytosine methylation within a CHH sequence|DNA methylation on cytosine within a CNN sequence|cytosine methylation within a CNN sequence													biological_process											owl:Class	
GO:0050108	biolink:NamedThing	monoterpenyl-diphosphatase activity	Catalysis of the reaction: monoterpenyl diphosphate + H2O = monoterpenol + diphosphate.	tmpzr1t_l9r_go_relaxed.owl	monoterpenyl-pyrophosphatase activity|bornyl diphosphate hydrolase activity|bornyl pyrophosphate hydrolase activity|monoterpenyl-diphosphate diphosphohydrolase activity				EC:3.1.7.3|MetaCyc:MONOTERPENYL-PYROPHOSPHATASE-RXN									molecular_function											owl:Class	
GO:1902056	biolink:NamedThing	(25S)-Delta(7)-dafachronate metabolic process	The chemical reactions and pathways involving (25S)-Delta(7)-dafachronate.	tmpzr1t_l9r_go_relaxed.owl	(25S)-Delta(7)-dafachronate metabolism							ab	2013-04-13T09:05:27Z					biological_process											owl:Class	
GO:0047449	biolink:NamedThing	2-dehydro-3-deoxy-L-arabinonate dehydratase activity	Catalysis of the reaction: 2-dehydro-3-deoxy-L-arabinonate = 2,5-dioxopentanoate + H(2)O.	tmpzr1t_l9r_go_relaxed.owl	2-dehydro-3-deoxy-L-arabinonate hydro-lyase (2,5-dioxopentanoate-forming)|2-keto-3-deoxy-L-arabinonate dehydratase activity|2-dehydro-3-deoxy-L-arabinonate hydro-lyase activity				EC:4.2.1.43|RHEA:17201|KEGG_REACTION:R02278|MetaCyc:4.2.1.43-RXN									molecular_function											owl:Class	
GO:0009401	biolink:NamedThing	phosphoenolpyruvate-dependent sugar phosphotransferase system	The uptake and phosphorylation of specific carbohydrates from the extracellular environment; uptake and phosphorylation are coupled, making the PTS a link between the uptake and metabolism of sugars; phosphoenolpyruvate is the original phosphate donor; phosphoenolpyruvate passes the phosphate via a signal transduction pathway, to enzyme 1 (E1), which in turn passes it on to the histidine protein, HPr; the next step in the system involves sugar-specific membrane-bound complex, enzyme 2 (EII), which transports the sugar into the cell; it includes the sugar permease, which catalyzes the transport reactions; EII is usually divided into three different domains, EIIA, EIIB, and EIIC.	tmpzr1t_l9r_go_relaxed.owl	PTS system													biological_process											owl:Class	
GO:0052818	biolink:NamedThing	heteroglycan 3-alpha-mannosyltransferase activity	Catalysis of the reaction: heteroglycan + GDP-mannose = (1->3)-alpha-D-mannosylheteroglycan + GDP.	tmpzr1t_l9r_go_relaxed.owl	guanosine diphosphomannose-heteroglycan 3-alpha-mannosyltransferase activity|heteropolysaccharide 3-alpha-mannosyltransferase activity|GDP mannose 3-alpha-mannosyltransferase activity|GDP-mannose:heteroglycan 3-alpha-D-mannosyltransferase activity				MetaCyc:RXN-7992|EC:2.4.1.48|KEGG_REACTION:R03769			ai	2011-10-27T12:36:10Z					molecular_function											owl:Class	
GO:1904952	biolink:NamedThing	hydroxycinnamic acid transport	The directed movement of a hydroxycinnamic acid into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl								lr	2016-02-05T22:00:38Z					biological_process											owl:Class	
GO:0050110	biolink:NamedThing	mucinaminylserine mucinaminidase activity	Catalysis of the reaction: D-galactosyl-3-(N-acetyl-beta-D-galactosaminyl)-L-serine + H2O = D-galactosyl-3-N-acetyl-beta-D-galactosamine + L-serine.	tmpzr1t_l9r_go_relaxed.owl	endo-beta-N-acetylgalactosaminidase|endo-beta-N-acetyl-D-galactosaminidase activity|D-galactosyl-3-(N-acetyl-beta-D-galactosaminyl)-L-serine mucinaminohydrolase activity				EC:3.2.1.97|MetaCyc:3.2.1.110-RXN|KEGG_REACTION:R04527									molecular_function											owl:Class	
GO:0006174	biolink:NamedThing	dADP phosphorylation	The process of introducing a phosphate group into dADP, deoxyadenosine diphosphate, to produce dATP.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0018748	biolink:NamedThing	iprodione amidohydrolase activity	Catalysis of the reaction: iprodione + OH- = 3,5-dichlorophenylcarboximide + N-isopropylcarbamate.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0706									molecular_function											owl:Class	
GO:0018948	biolink:NamedThing	xylene metabolic process	The chemical reactions and pathways involving xylene, a mixture of three colorless, aromatic hydrocarbon liquids, ortho-, meta- and para-xylene.	tmpzr1t_l9r_go_relaxed.owl	xylene metabolism													biological_process											owl:Class	
GO:0071196	biolink:NamedThing	Kv4.3-KChIP1 channel complex	A voltage-gated potassium channel complex that contains the Kv channel interacting protein KChIP1 associated with the channel via interaction with the Kv alpha subunit 4.3.	tmpzr1t_l9r_go_relaxed.owl					CORUM:3091			mah	2009-11-23T04:59:38Z					cellular_component											owl:Class	
GO:0150137	biolink:NamedThing	interleukin-37 production	The appearance of interleukin-37 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	tmpzr1t_l9r_go_relaxed.owl	interleukin-37 biosynthetic process							bc	2019-12-08T08:43:09Z					biological_process											owl:Class	
GO:0014845	biolink:NamedThing	stomach body smooth muscle contraction	A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the body of stomach. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The body of stomach is the part of the stomach that lies between the fundus above and the pyloric antrum below; its boundaries are poorly defined.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0007387	biolink:NamedThing	anterior compartment pattern formation	The process giving rise to specification of cell identity in the anterior compartments of the segmented embryo.	tmpzr1t_l9r_go_relaxed.owl	anterior compartment pattern specification													biological_process											owl:Class	
GO:0034527	biolink:NamedThing	1,2-dihydroxy-8-carboxynaphthalene dioxygenase activity	Catalysis of the reaction: 1,2-dihydroxy-8-carboxynaphthalene + O2 = 2-carboxy-2-hydroxy-8-carboxychromene.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0790									molecular_function											owl:Class	
GO:1990300	biolink:NamedThing	cellulosome binding	Binding to a cellulosome, an extracellular multi-enzyme complex containing several enzymes aligned on a non-catalytic scaffolding that functions to hydrolyze plant cell wall polysaccharides.	tmpzr1t_l9r_go_relaxed.owl	scaffoldin complex binding								2014-02-26T22:41:22Z			GO:1990301		molecular_function											owl:Class	
GO:0048867	biolink:NamedThing	stem cell fate determination	The process in which a cell becomes capable of differentiating autonomously into a stem cell regardless of its environment; upon determination, the cell fate cannot be reversed.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0102756	biolink:NamedThing	very-long-chain 3-ketoacyl-CoA synthase activity	Catalysis of the reaction: malonyl-CoA + a very-long-chain 2,3,4-saturated fatty acyl CoA = carbon dioxide + coenzyme A + a very-long-chain oxoacyl-CoA.	tmpzr1t_l9r_go_relaxed.owl					RHEA:32727|MetaCyc:RXN-7697|EC:2.3.1.199									molecular_function											owl:Class	
GO:0005005	biolink:NamedThing	transmembrane-ephrin receptor activity	Combining with a transmembrane ephrin to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	transmembrane-Eph receptor activity													molecular_function											owl:Class	
GO:0060207	biolink:NamedThing	diestrus	The estrous cycle phase which is a period of sexual quiescence and represents the phase of the mature corpus luteum.	tmpzr1t_l9r_go_relaxed.owl						Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase. To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).								biological_process											owl:Class	
GO:0001010	biolink:NamedThing	RNA polymerase II sequence-specific DNA-binding transcription factor recruiting activity	The function of binding to a specific DNA sequence and recruiting another transcription factor to the DNA in order to modulate transcription. The recruited factor may bind DNA directly, or may be colocalized via protein-protein interactions.	tmpzr1t_l9r_go_relaxed.owl	sequence-specific DNA binding transcription factor recruiting transcription factor activity|transcription factor activity, sequence-specific DNA-binding transcription factor recruiting|transcription factor activity, sequence-specific DNA binding transcription factor recruiting							krc	2010-08-18T06:46:33Z					molecular_function											owl:Class	
GO:0018556	biolink:NamedThing	2,2',3-trihydroxybiphenyl dioxygenase activity	Catalysis of the reaction: 2,3-dihydroxybenzenoid + O2 = H+ + distal extradiol ring cleavage. Substrates are 2,2',3-trihydroxybiphenyl (forms 2-hydroxy-6-oxo-6-(2-hydroxyphenyl)-hexa-2,4-dienoate) and 2,2',3-trihydroxydiphenylether (forms 2,3-hydroxy-6-oxo-6-(2-hydroxyphenyl)-hexa-2,4-dienoate).	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_enzymeID:e0032|EC:1.13.11.-									molecular_function											owl:Class	
GO:0097589	biolink:NamedThing	archaeal-type flagellum	A non-membrane-bounded organelle superficially similar to a bacterial-type flagellum; they both consist of filaments extending outside the cell, and rotate to propel the cell, but the archaeal flagella (also called archaella) have a unique structure which lacks a central channel. Similar to bacterial type IV pilins, the archaeal flagellins (archaellins) are made with class 3 signal peptides and they are processed by a type IV prepilin peptidase-like enzyme. The archaellins are typically modified by the addition of N-linked glycans which are necessary for proper assembly and/or function.	tmpzr1t_l9r_go_relaxed.owl	archaeal flagellum|archaellum|archaella							pr	2014-03-25T20:36:24Z					cellular_component											owl:Class	
GO:0010402	biolink:NamedThing	pectic arabinan metabolic process	The chemical reactions and pathways involving pectic arabinan, a polymer with an alpha-(1->5)-linked L-arabinofuranose (Araf) backbone that can be substituted with Araf-alpha-(1->2)-, Araf-alpha-(1->3)-, and/or Araf-alpha-(1->3)-Araf-alpha-(1->3)-side chains. Arabinan can be found as a side chain of the pectin rhamnogalacturonan I.	tmpzr1t_l9r_go_relaxed.owl	pectic arabinan metabolism													biological_process											owl:Class	
GO:0060469	biolink:NamedThing	positive regulation of transcription involved in egg activation	Any process that increases the rate, frequency or extent of transcription as a part of the process of egg activation.	tmpzr1t_l9r_go_relaxed.owl	activation of the maternal genome|activation of the egg genome													biological_process											owl:Class	
GO:0010047	biolink:NamedThing	fruit dehiscence	The process leading to the spontaneous opening of the fruit permitting the escape of seeds.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0140490	biolink:NamedThing	microtubule nucleator activity	The action of a molecule that provides a shape mimicking the end of a microtubule to seed the formation of a new microtubule via self-assembly.	tmpzr1t_l9r_go_relaxed.owl	microtubule nucleation template activity	https://github.com/geneontology/go-ontology/issues/19709						pg	2020-07-01T08:47:54Z					molecular_function											owl:Class	
GO:0047645	biolink:NamedThing	alkan-1-ol dehydrogenase (acceptor) activity	Catalysis of the reaction: primary alcohol + acceptor = aldehyde + reduced acceptor.	tmpzr1t_l9r_go_relaxed.owl	alkan-1-ol:acceptor oxidoreductase activity|alkan-1-ol:(acceptor) oxidoreductase activity|polyethylene glycol dehydrogenase activity				MetaCyc:ALKAN-1-OL-DEHYDROGENASE-ACCEPTOR-RXN|EC:1.1.99.20|RHEA:14685									molecular_function											owl:Class	
GO:0140381	biolink:NamedThing	4-hydroxytryptamine 4-phosphate methyltransferase activity	Catalysis of the reaction: 2 S-adenosyl-L-methionine (SAM) + 4-hydroxytryptamine 4-phosphate (norbaeocystin) <=> 2 S-adenosyl-L-homocysteine + psilocybin.	tmpzr1t_l9r_go_relaxed.owl	psilocybin synthase|norbaeocystin methyltransferase				EC:2.1.1.345|RHEA:55568			pg	2019-11-20T10:16:28Z					molecular_function											owl:Class	
GO:0051571	biolink:NamedThing	positive regulation of histone H3-K4 methylation	Any process that activates or increases the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 4 of histone H3.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of histone H3-K4 methylation|stimulation of histone H3-K4 methylation|upregulation of histone H3-K4 methylation|activation of histone H3-K4 methylation|up regulation of histone H3-K4 methylation													biological_process											owl:Class	
GO:0033225	biolink:NamedThing	ATPase-coupled 2-aminoethylphosphonate transporter activity	Enables the directed movement of 2-aminoethylphosphonate from one side of a membrane to the other by catalysis of the reaction: ATP + H2O + 2-aminoethylphosphonate(out) = ADP + phosphate + 2-aminoethylphosphonate(in).	tmpzr1t_l9r_go_relaxed.owl	ciliatine transporter activity|2-phosphonoethylamine transporting ATPase activity|2-aminoethylphosphonate-transporting ATPase activity|2-phosphonoethylamine transmembrane transporter activity|ATP-dependent 2-aminoethylphosphonate transporter activity|2-aminoethylphosphonate transmembrane transporter activity|2-aminoethylphosphonate transporting ATPase activity|ciliatine transportingATPase activity				RHEA:32775	There is no annotated example of this MF; therefore we cannot classify it more precisely.						GO:0033224		molecular_function											owl:Class	
GO:1905703	biolink:NamedThing	negative regulation of inhibitory synapse assembly	Any process that stops, prevents or reduces the frequency, rate or extent of inhibitory synapse assembly.	tmpzr1t_l9r_go_relaxed.owl	down regulation of inhibitory synapse formation|inhibition of inhibitory synapse assembly|downregulation of inhibitory synapse assembly|negative regulation of inhibitory synapse formation|inhibition of inhibitory synapse formation|down regulation of inhibitory synapse assembly|down-regulation of inhibitory synapse formation|downregulation of inhibitory synapse formation|down-regulation of inhibitory synapse assembly							tb	2016-11-16T18:55:40Z					biological_process											owl:Class	
GO:0070463	biolink:NamedThing	tubulin-dependent ATPase activity	Catalysis of the reaction: ATP + H2O = ADP + phosphate. This reaction requires the presence of a tubulin dimer to accelerate release of ADP and phosphate.	tmpzr1t_l9r_go_relaxed.owl	tubulin-activated ATPase activity													molecular_function											owl:Class	
GO:0075530	biolink:NamedThing	establishment of latency as a linear episome	A process by which a virus establishes a latent state within its host as an episome, where the viral genome remains silent in the cytoplasm or nucleus as linear structure.	tmpzr1t_l9r_go_relaxed.owl	establishment of linear plasmid latency|establishment of latency as a linear plasmid							jl	2011-08-04T03:14:23Z					biological_process											owl:Class	
GO:0047786	biolink:NamedThing	cortisone alpha-reductase activity	Catalysis of the reaction: 4,5alpha-dihydrocortisone + NADP(+) = cortisone + H(+) + NADPH.	tmpzr1t_l9r_go_relaxed.owl	microsomal steroid reductase (5alpha)|delta4-3-ketosteroid reductase (5alpha)|delta4-5alpha-reductase activity|4,5alpha-dihydrocortisone:NADP+ delta4-oxidoreductase activity|delta4-3-oxosteroid-5alpha-reductase|cortisone a-reductase activity|NADPH:Delta4-3-oxosteroid-5alpha-oxidoreductase activity|cortisone delta4-5alpha-reductase activity				KEGG_REACTION:R02892|RHEA:17981|MetaCyc:CORTISONE-ALPHA-REDUCTASE-RXN									molecular_function											owl:Class	
GO:0011000	biolink:NamedThing	replication fork arrest at mating type locus	A process that impedes the progress of the DNA replication fork at natural replication fork pausing sites within the mating type locus.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-06-24T12:02:48Z					biological_process											owl:Class	
GO:0046331	biolink:NamedThing	lateral inhibition	Signaling between cells of equivalent developmental potential that results in these cells adopting different developmental fates. An example is the suppression by cells with a particular fate of the adoption of the same fate by surrounding cells.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0086053	biolink:NamedThing	AV node cell to bundle of His cell communication by electrical coupling	The process that mediates signaling interactions between an AV node cardiomyocyte and a bundle of His cardiac muscle cell by transfer of current between their adjacent cytoplasms via intercellular protein channels.	tmpzr1t_l9r_go_relaxed.owl	atrioventricular node cell to bundle of His cell communication by electrical coupling							dph	2011-11-16T12:31:08Z					biological_process											owl:Class	
GO:0051896	biolink:NamedThing	regulation of protein kinase B signaling	Any process that modulates the frequency, rate or extent of protein kinase B signaling, a series of reactions mediated by the intracellular serine/threonine kinase protein kinase B.	tmpzr1t_l9r_go_relaxed.owl	regulation of AKT signaling cascade|regulation of PKB signaling cascade|regulation of protein kinase B signaling cascade|regulation of PKB signalling cascade|regulation of AKT signalling cascade|regulation of protein kinase B signalling cascade													biological_process											owl:Class	
GO:1990463	biolink:NamedThing	lateral cortical node	A protein complex that is anchored at the cortical face of the plasma membrane, and contains proteins involved in regulating cell cycle progression. In Schizosaccharomyces pombe, lateral cortical nodes are several megadaltons in size, and contain Slf1, which anchors the complex at the membrane, and the methyltransferase Skb1 in stoichiometric quantities, and may contain other proteins.	tmpzr1t_l9r_go_relaxed.owl	Skb1-containing cortical node							pr	2014-08-20T09:04:45Z					cellular_component											owl:Class	
GO:0047524	biolink:NamedThing	16-hydroxysteroid epimerase activity	Catalysis of the reaction: 16-alpha-hydroxysteroid = 16-beta-hydroxysteroid.	tmpzr1t_l9r_go_relaxed.owl	16-hydroxysteroid 16-epimerase activity				RHEA:15829|MetaCyc:16-HYDROXYSTEROID-EPIMERASE-RXN|EC:5.1.99.2									molecular_function											owl:Class	
GO:1902346	biolink:NamedThing	meiotic strand displacement involved in double-strand break repair via SDSA	Any meiotic strand displacement that is involved in double-strand break repair via synthesis-dependent strand annealing (SDSA).	tmpzr1t_l9r_go_relaxed.owl	meiotic strand displacement involved in SDSA|meiotic D-loop dissociation involved in mitotic gene conversion|meiotic displacement loop processing involved in mitotic gene conversion|meiotic strand displacement involved in mitotic gene conversion|meiotic displacement loop processing involved in double-strand break repair via synthesis-dependent strand annealing|meiotic displacement loop dissociation involved in mitotic gene conversion|meiotic displacement loop dissociation involved in double-strand break repair via synthesis-dependent strand annealing|meiotic D-loop processing involved in mitotic gene conversion|meiotic strand displacement involved in double-strand break repair via synthesis-dependent strand annealing|meiotic D-loop processing involved in double-strand break repair via synthesis-dependent strand annealing|meiotic D-loop dissociation involved in double-strand break repair via synthesis-dependent strand annealing							pr	2013-08-07T12:56:20Z					biological_process											owl:Class	
GO:0000714	biolink:NamedThing	meiotic strand displacement	The cell cycle process in which the broken 3' single-strand DNA molecule that formed heteroduplex DNA with its complement in an intact duplex DNA is rejected. The Watson-Crick base pairing in the original duplex is restored. The rejected 3' single-strand DNA molecule reanneals with its original complement to reform two intact duplex molecules. This occurs during meiosis.	tmpzr1t_l9r_go_relaxed.owl	meiotic displacement loop processing|meiotic D-loop dissociation|meiotic D-loop processing|meiotic displacement loop dissociation													biological_process											owl:Class	
GO:0050531	biolink:NamedThing	mannosyl-3-phosphoglycerate phosphatase activity	Catalysis of the reaction: 2-(alpha-D-mannosyl)-3-phosphoglycerate + H(2)O = 2-(alpha-D-mannosyl)-D-glycerate + phosphate.	tmpzr1t_l9r_go_relaxed.owl	alpha-D-mannosyl-3-phosphoglycerate phosphohydrolase activity				RHEA:19309|EC:3.1.3.70|MetaCyc:3.1.3.70-RXN|KEGG_REACTION:R05790									molecular_function											owl:Class	
GO:0106330	biolink:NamedThing	sialate 9-O-acetylesterase activity	Catalysis of the reaction: H2O + N-acetyl-9-O-acetylneuraminate = acetate + H(+) + N-acetylneuraminate.	tmpzr1t_l9r_go_relaxed.owl					RHEA:22600|EC:3.1.1.53			hjd	2020-09-30T19:38:44Z					molecular_function											owl:Class	
GO:0010690	biolink:NamedThing	negative regulation of ribosomal protein gene transcription from RNA polymerase II promoter in response to stress	Any process that decreases the frequency, rate or extent of the synthesis of RNA from ribosomal protein genes by RNA polymerase II, originating at an RNA polymerase II promoter, as a result of a disturbance in organismal or cellular homeostasis.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0046100	biolink:NamedThing	hypoxanthine metabolic process	The chemical reactions and pathways involving hypoxanthine, 6-hydroxy purine, an intermediate in the degradation of adenylate. Its ribonucleoside is known as inosine and its ribonucleotide as inosinate.	tmpzr1t_l9r_go_relaxed.owl	hypoxanthine metabolism													biological_process											owl:Class	
GO:0004836	biolink:NamedThing	tyramine-beta hydroxylase activity	Catalysis of the hydroxylation of tyramine to form octopamine.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0005516	biolink:NamedThing	calmodulin binding	Binding to calmodulin, a calcium-binding protein with many roles, both in the calcium-bound and calcium-free states.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0052748	biolink:NamedThing	baicalin beta-D-glucuronidase activity	Catalysis of the reaction: baicalin + H2O = baicalein + D-glucuronate.	tmpzr1t_l9r_go_relaxed.owl	5,6,7-trihydroxyflavone-7-O-beta-D-glucupyranosiduronate glucuronosylhydrolase activity|baicalinase activity				KEGG_REACTION:R09533|EC:3.2.1.167|MetaCyc:RXN-11760|RHEA:28130			ai	2011-09-21T12:58:43Z					molecular_function											owl:Class	
GO:0035096	biolink:NamedThing	larval midgut cell programmed cell death	The stage-specific programmed cell death of cells of the larval midgut, during histolysis of the larval organ.	tmpzr1t_l9r_go_relaxed.owl	larval midgut cell death|programmed cell death of larval midgut cells													biological_process											owl:Class	
GO:0036530	biolink:NamedThing	protein deglycation, methylglyoxal removal	The removal of methylglyoxal from a glycated protein, to form lactate and a deglycated protein.	tmpzr1t_l9r_go_relaxed.owl	protein deglycation of methylglyoxal-glycated protein							bf	2016-08-04T10:42:26Z					biological_process											owl:Class	
GO:0019635	biolink:NamedThing	2-aminoethylphosphonate catabolic process	The chemical reactions and pathways resulting in the breakdown of 2-aminoethylphosphonate, also known as ciliatine.	tmpzr1t_l9r_go_relaxed.owl	ciliatine catabolic process|ciliatine catabolism|2-aminoethylphosphonate degradation|2-aminoethylphosphonate catabolism|2-phosphonoethylamine catabolism|2-phosphonoethylamine catabolic process|2-aminoethylphosphonate breakdown				MetaCyc:PHOSPHONOTASE-PWY									biological_process											owl:Class	
GO:0060805	biolink:NamedThing	negative regulation of trophoblast cell differentiation by transcription regulation from RNA polymerase II promoter	Any process that modulates the rate, frequency or extent of transcription from an RNA polymerase II promoter ultimately resulting in a decrease in trophoblast stem cells differentiating into the more mature cells of the trophoblast.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-08-06T01:58:25Z					biological_process											owl:Class	
GO:0015571	biolink:NamedThing	N-acetylgalactosamine transmembrane transporter activity	Enables the transfer of N-acetylgalactosamine from one side of a membrane to the other. N-acetylgalactosamine, 2-acetamido-2-deoxygalactopyranose, is the n-acetyl derivative of galactosamine.	tmpzr1t_l9r_go_relaxed.owl	N-acetylgalactosamine permease activity											GO:0015590		molecular_function											owl:Class	
GO:0032532	biolink:NamedThing	regulation of microvillus length	A process that modulates the length of a microvillus.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0043529	biolink:NamedThing	GET complex	An endoplasmic reticulum protein-containing complex that is conserved in eukaryotics and that mediates the insertion of tail-anchored proteins into the ER membrane. In yeast, includes Get1p, Get2p and Get3p proteins.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/20244												cellular_component											owl:Class	
GO:0050985	biolink:NamedThing	peptidyl-threonine sulfation	The sulfation of peptidyl-threonine to form peptidyl-O-sulfo-L-threonine.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0362									biological_process											owl:Class	
GO:1905773	biolink:NamedThing	8-hydroxy-2'-deoxyguanosine DNA binding	Binding to 8-hydroxy-2'-deoxyguanosine an oxidized purine residue found in damaged DNA.	tmpzr1t_l9r_go_relaxed.owl								nc	2016-12-21T15:57:27Z					molecular_function											owl:Class	
GO:0120225	biolink:NamedThing	coenzyme A binding	Binding to coenzyme A, 3'-phosphoadenosine-(5')diphospho(4')pantatheine, an acyl carrier in many acylation and acyl-transfer reactions in which the intermediate is a thiol ester.	tmpzr1t_l9r_go_relaxed.owl	CoA binding							krc	2020-05-06T18:22:56Z					molecular_function											owl:Class	
GO:0032033	biolink:NamedThing	myosin II light chain binding	Binding to a light chain of a myosin II complex.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0017054	biolink:NamedThing	negative cofactor 2 complex	A heterodimeric protein complex that can stably associate with TATA-binding protein on promoters, thereby preventing the assembly of transcription factors TFIIA and TFIIB and leading to repression of RNA polymerase II transcription. The two subunits, NC2alpha (Drap1) and NC2beta (Dr1), dimerize through histone fold domains of the H2A/H2B type present in the amino termini.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0019256	biolink:NamedThing	acrylonitrile catabolic process	The chemical reactions and pathways resulting in the breakdown of acrylonitrile, a colorless, volatile liquid with a pungent odor. Acrylonitrile is used in the production of acrylic fibers, plastics, and synthetic rubbers.	tmpzr1t_l9r_go_relaxed.owl	acrylonitrile breakdown|acrylonitrile degradation|acrylonitrile catabolism				MetaCyc:P344-PWY									biological_process											owl:Class	
GO:0061409	biolink:NamedThing	positive regulation of transcription from RNA polymerase II promoter in response to freezing	Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a freezing stimulus, temperatures below 0 degrees Celsius.	tmpzr1t_l9r_go_relaxed.owl								dph	2012-01-12T12:11:06Z					biological_process											owl:Class	
GO:0046423	biolink:NamedThing	allene-oxide cyclase activity	Catalysis of the reaction: (9Z,13S,15Z)-12,13-epoxyoctadeca-9,11,15-trienoate = (15Z)-12-oxophyto-10,15-dienoate.	tmpzr1t_l9r_go_relaxed.owl	(9Z)-(13S)-12,13-epoxyoctadeca-9,11,15-trienoate isomerase (cyclizing)				RHEA:22592|MetaCyc:ALLENE-OXIDE-CYCLASE-RXN|KEGG_REACTION:R03402|EC:5.3.99.6									molecular_function											owl:Class	
GO:0102625	biolink:NamedThing	cirsimaritin 4'-O-methyltransferase activity	Catalysis of the reaction: cirsimaritin + S-adenosyl-L-methionine  <=> salvigenin + S-adenosyl-L-homocysteine  + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-15530									molecular_function											owl:Class	
GO:1990310	biolink:NamedThing	type-III dockerin domain binding	Binding to a type-III dockerin domain of a protein. Type-III dockerin domain is the binding partner of type-III cohesin domain.	tmpzr1t_l9r_go_relaxed.owl								tt	2014-03-07T03:22:36Z					molecular_function											owl:Class	
GO:0008116	biolink:NamedThing	prostaglandin-I synthase activity	Catalysis of the reaction: prostaglandin H(2) = prostaglandin I(2).	tmpzr1t_l9r_go_relaxed.owl	PGI2 synthase activity|PGI(2) synthetase activity|PGI(2) synthase activity|prostacyclin synthase activity|PGI2 synthetase activity|prostacycline synthetase activity|(5Z,13E)-(15S)-9alpha,11alpha-epidioxy-15-hydroxyprosta-5,13-dienoate 6-isomerase activity|prostagladin I2 synthetase activity|cytochrome P450 CYP8A1				EC:5.3.99.4|RHEA:23580|KEGG_REACTION:R02267|Reactome:R-HSA-76496|MetaCyc:PROSTAGLANDIN-I-SYNTHASE-RXN									molecular_function											owl:Class	
GO:0047824	biolink:NamedThing	D-iditol 2-dehydrogenase activity	Catalysis of the reaction: D-iditol + NAD+ = D-sorbose + NADH.	tmpzr1t_l9r_go_relaxed.owl					RHEA:12725|MetaCyc:D-IDITOL-2-DEHYDROGENASE-RXN|EC:1.1.1.15									molecular_function											owl:Class	
GO:0090660	biolink:NamedThing	cerebrospinal fluid circulation	The neurological system process driven by motile cilia on ependymal cells of the brain by which cerebrospinal fluid circulates from the sites of secretion to the sites of absorption. In ventricular cavities, the flow is unidirectional and rostrocaudal, in subarachnoid spaces, the flow is multi-directional.	tmpzr1t_l9r_go_relaxed.owl	CSF circulation|cerebrospinal fluid flow|CSF flow							tb	2015-09-11T15:49:59Z					biological_process											owl:Class	
GO:0140212	biolink:NamedThing	regulation of long-chain fatty acid import into cell	Any process that modulates the frequency, rate or extent of long-chain fatty acid import into a cell.	tmpzr1t_l9r_go_relaxed.owl								pg	2018-04-10T15:10:41Z					biological_process											owl:Class	
GO:2001081	biolink:NamedThing	(1->4)-beta-D-galactan binding	Binding to (1->4)-beta-D-galactan.	tmpzr1t_l9r_go_relaxed.owl	(1,4)-beta-D-galactan binding							jl	2011-09-15T01:21:50Z					molecular_function											owl:Class	
GO:0071529	biolink:NamedThing	cementum mineralization	The process in which calcium salts, mainly carbonated hydroxyapatite, are deposited into the initial acellular cementum.	tmpzr1t_l9r_go_relaxed.owl	cementum formation							mah	2010-01-07T04:18:54Z					biological_process											owl:Class	
GO:0021619	biolink:NamedThing	hypoglossal nerve maturation	A developmental process, independent of morphogenetic (shape) change, that is required for the hypoglossal nerve to attain its fully functional state. This motor nerve innervates all the intrinsic and all but one of the extrinsic muscles of the tongue.	tmpzr1t_l9r_go_relaxed.owl	CN XII maturation													biological_process											owl:Class	
GO:0102829	biolink:NamedThing	ajugose synthase activity	Catalysis of the reaction: 2 verbascose <=> ajugose + stachyose.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-8285									molecular_function											owl:Class	
GO:0052579	biolink:NamedThing	(+)-pulegone reductase, (+)-isomenthone as substrate, activity	Catalysis of the reaction: (+)-isomenthone + NADP+ = (+)-pulegone + NADPH + H+.	tmpzr1t_l9r_go_relaxed.owl	(+)-isomenthone:NADP+ oxidoreductase activity				MetaCyc:RXN-5164|EC:1.3.1.81			ai	2010-08-09T04:28:00Z					molecular_function											owl:Class	
GO:0097156	biolink:NamedThing	fasciculation of motor neuron axon	The collection of motor neuron axons into a bundle of rods, known as a fascicle.	tmpzr1t_l9r_go_relaxed.owl								pr	2011-09-16T09:20:46Z					biological_process											owl:Class	
GO:0097372	biolink:NamedThing	NAD-dependent histone deacetylase activity (H3-K18 specific)	Catalysis of the reaction: histone H3 N6-acetyl-L-lysine (position 18) + H2O = histone H3 L-lysine (position 18) + acetate. This reaction requires the presence of NAD, and represents the removal of an acetyl group from lysine at position 18 of the histone H3 protein.	tmpzr1t_l9r_go_relaxed.owl								pr	2012-09-05T13:16:39Z					molecular_function											owl:Class	
GO:0052545	biolink:NamedThing	callose localization	Any process in which callose is transported to, and/or maintained in, a specific location. Callose is a linear 1,3-beta-d-glucan formed from UDP-glucose and is found in certain plant cell walls.	tmpzr1t_l9r_go_relaxed.owl	callose localisation													biological_process											owl:Class	
GO:0102972	biolink:NamedThing	gibberellin A12,2-oxoglutarate:oxygen oxidoreductase activity (gibberellin A110-forming)	Catalysis of the reaction: gibberellin A12 + 2-oxoglutarate + O2 = gibberellin A110 + succinate + carbon dioxide.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-947									molecular_function											owl:Class	
GO:0000113	biolink:NamedThing	nucleotide-excision repair factor 4 complex	One of several protein complexes involved in nucleotide-excision repair; possesses DNA damage recognition and DNA-dependent ATPase activities. In S. cerevisiae, it is composed of Rad7p and Rad16p.	tmpzr1t_l9r_go_relaxed.owl	NEF4 complex					Note that process and function information are included in the term and definition for the purpose of describing and distinguishing the complex.								cellular_component											owl:Class	
GO:0102466	biolink:NamedThing	beta-carotene 2,2'-beta-hydroxylase activity	Catalysis of the reaction: beta-carotene + 2 NADH + 2 H+ + 2 O2 = (2R,2'R)-dihydroxy-all-trans-beta-carotene + 2 NAD + 2 H2O.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-14019									molecular_function											owl:Class	
GO:0070110	biolink:NamedThing	ciliary neurotrophic factor receptor complex	A protein complex that acts as a receptor for the cytokine ciliary neurotrophic factor (CNTF). In humans the receptor complex is a hexamer composed of two molecules each of CNTF and CNTFR and one molecule each of gp130 and LIFR.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0019331	biolink:NamedThing	anaerobic respiration, using ammonium as electron donor	The oxidation of ammonium (NH4) to nitrogen (N2) in the absence of oxygen, using nitrite (NO2) as the electron acceptor. It is suggested that hydroxylamine and ammonium are combined to yield hydrazine, which is subsequently oxidized to N2.	tmpzr1t_l9r_go_relaxed.owl	anammox|anaerobic ammonium oxidation				Wikipedia:Anammox|MetaCyc:P303-PWY									biological_process											owl:Class	
GO:0102536	biolink:NamedThing	sakuranetin 6-hydroxylase activity	Catalysis of the reaction: sakuranetin + O2 + NADPH + H+ <=> carthamidin-7-methyl ether + H2O + NADP.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-14754									molecular_function											owl:Class	
GO:0050343	biolink:NamedThing	trans-2-enoyl-CoA reductase (NAD+) activity	Catalysis of the reaction: acyl-CoA + NAD+ = trans-didehydroacyl-CoA + NADH.	tmpzr1t_l9r_go_relaxed.owl	acyl-CoA:NAD+ trans-2-oxidoreductase activity				EC:1.3.1.44|MetaCyc:TRANS-2-ENOYL-COA-REDUCTASE-NAD+-RXN|RHEA:18177									molecular_function											owl:Class	
GO:0043338	biolink:NamedThing	CTP:2,3-di-O-geranylgeranyl-sn-glycero-1-phosphate cytidyltransferase activity	Catalysis of the reaction: CTP + 2,3-di-O-geranylgeranyl-sn-glycero-1-phosphate = CDP-2,3-di-O-geranylgeranyl-sn-glycerol.	tmpzr1t_l9r_go_relaxed.owl	CDP-2,3-di-O-geranylgeranyl-sn-glycerol synthase				EC:2.7.7.67|RHEA:25690									molecular_function											owl:Class	
GO:0000937	biolink:NamedThing	dolipore septum	A septum, or cross-wall, between two portions of a cell or hypha; contains a central pore around which the septum is swollen to form a barrel-shaped structure; pore is covered on each side of the septum by a septal pore cap (parenthosome).	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0033937	biolink:NamedThing	3-deoxy-2-octulosonidase activity	Catalysis of the endohydrolysis of the beta-ketopyranosidic linkages of 3-deoxy-D-manno-2-octulosonate in capsular polysaccharides.	tmpzr1t_l9r_go_relaxed.owl	octulosylono hydrolase activity|octulofuranosylono hydrolase activity|2-keto-3-deoxyoctonate hydrolase activity|capsular-polysaccharide 3-deoxy-D-manno-2-octulosonohydrolase activity|octulopyranosylonohydrolase activity				EC:3.2.1.124|MetaCyc:3.2.1.124-RXN									molecular_function											owl:Class	
GO:0035334	biolink:NamedThing	Notch receptor processing, ligand-independent	The proteolytic cleavages to the Notch protein that occur prior to ligand binding. A primary cleavage event within the extracellular domain whilst the Notch protein in still in the secretory pathway, leads to the transportation of a processed heterodimer to the cell surface.	tmpzr1t_l9r_go_relaxed.owl	Notch S1 cleavage							bf	2010-02-26T02:32:46Z					biological_process											owl:Class	
GO:0032014	biolink:NamedThing	positive regulation of ARF protein signal transduction	Any process that activates or increases the frequency, rate or extent of ARF protein signal transduction.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of ARF protein signal transduction|activation of ARF protein signal transduction|up regulation of ARF protein signal transduction|stimulation of ARF protein signal transduction|upregulation of ARF protein signal transduction													biological_process											owl:Class	
GO:0097611	biolink:NamedThing	dinoflagellate cingulum	A cell surface furrow that wraps around a dinoflagellate cell; the transverse flagellum lies in it.	tmpzr1t_l9r_go_relaxed.owl	girdle|cingulum|transverse groove					The term name refers to a taxonomic group to make the label unique with respect to similarly-named anatomical structures.		pr	2014-06-09T11:28:22Z					cellular_component											owl:Class	
GO:0062061	biolink:NamedThing	TAP complex binding	Binding to a TAP complex.	tmpzr1t_l9r_go_relaxed.owl								dph	2018-08-31T13:54:22Z					molecular_function											owl:Class	
GO:0070311	biolink:NamedThing	nucleosomal methylation activator complex	A protein complex that contains eight subunits in common with the SWI/SNF complex, plus the ATPase BRG1 (SMARCA4) and the histone methyltransferase CARM1; the complex is involved in regulating nuclear receptor-dependent transcription.	tmpzr1t_l9r_go_relaxed.owl	NUMAC													cellular_component											owl:Class	
GO:0106319	biolink:NamedThing	(R)-limonene 1,2-monooxygenase NADH activity	Catalysis of the reaction: (4R)-limonene + NADH + H+ + O2 = NAD+ + H2O + (4R)-limonene-1,2-epoxide.	tmpzr1t_l9r_go_relaxed.owl					EC:1.14.13.107|RHEA:26093			hjd	2020-09-23T15:20:27Z					molecular_function											owl:Class	
GO:0098892	biolink:NamedThing	extrinsic component of postsynaptic specialization membrane	The component of the postsynaptic specialization membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0061793	biolink:NamedThing	chromatin lock complex	A chromatin silencing complex that binds and bridges separate nucleosomal histones resulting in heterochromatin assembly and chromatin looping.	tmpzr1t_l9r_go_relaxed.owl	nucleosome bridging complex							dph	2016-09-09T13:47:27Z					cellular_component											owl:Class	
GO:0000246	biolink:NamedThing	delta24(24-1) sterol reductase activity	Catalysis of the reaction: ergosterol + NADP(+) = ergosta-5,7,22,24(24(1))-tetraen-3beta-ol + H(+) + NADPH.	tmpzr1t_l9r_go_relaxed.owl	sterol delta24(28)-methylene reductase activity|C-24(28) sterol reductase activity|D24(24-1)-sterol reductase activity|sterol delta-24(28) methylene reductase activity|sterol Delta(24(28))-reductase activity|sterol delta-24(28) reductase activity|ergosterol:NADP+ delta24(241)-oxidoreductase activity|sterol delta24(28)-reductase activity|delta24(241)-sterol reductase activity|sterol Delta(24(28))-methylene reductase activity				MetaCyc:1.3.1.71-RXN|KEGG_REACTION:R05641|RHEA:18501|EC:1.3.1.71									molecular_function											owl:Class	
GO:0080172	biolink:NamedThing	petal epidermis patterning	The regionalization process that regulates the coordinated growth and establishes the non-random spatial arrangement of the cells in the petal epidermis.	tmpzr1t_l9r_go_relaxed.owl								dhl	2011-04-25T04:44:06Z					biological_process											owl:Class	
GO:0030908	biolink:NamedThing	protein splicing	The post-translational removal of peptide sequences from within a protein sequence.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Protein_splicing									biological_process											owl:Class	
GO:0031889	biolink:NamedThing	urotensin receptor binding	Binding to a urotensin receptor.	tmpzr1t_l9r_go_relaxed.owl	urotensin receptor ligand													molecular_function											owl:Class	
GO:0016314	biolink:NamedThing	phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity	Catalysis of the reaction: phosphatidylinositol-3,4,5-trisphosphate + H2O = phosphatidylinositol-4,5-bisphosphate + phosphate.	tmpzr1t_l9r_go_relaxed.owl	PtdIns(3,4,5)P3 3-phosphatase activity|1-phosphatidyl-1D-myo-inositol-3,4,5-trisphosphate 3-phosphohydrolase activity|PI(3,4,5)P3 3-phosphatase activity|PI(3)P 3-phosphatase activity|phosphatidylinositol-3,4,5-trisphosphate 3-phosphohydrolase activity|MMAC1				Reactome:R-HSA-2317387|RHEA:25017|EC:3.1.3.67|Reactome:R-HSA-199456|MetaCyc:3.1.3.67-RXN|Reactome:R-HSA-202237									molecular_function											owl:Class	
GO:0044686	biolink:NamedThing	cysteate synthase activity	Catalysis of the reaction: L-phosphoserine + SO32- = L-cysteate + HPO4-.	tmpzr1t_l9r_go_relaxed.owl					EC:2.5.1.76|MetaCyc:RXN-11108|RHEA:26486			jl	2012-08-15T14:16:05Z					molecular_function											owl:Class	
GO:1900777	biolink:NamedThing	fumiquinazoline A catabolic process	The chemical reactions and pathways resulting in the breakdown of fumiquinazoline A.	tmpzr1t_l9r_go_relaxed.owl	fumiquinazoline A degradation|fumiquinazoline A breakdown|fumiquinazoline A catabolism							di	2012-06-04T09:30:18Z					biological_process											owl:Class	
GO:0018567	biolink:NamedThing	styrene dioxygenase activity	Catalysis of the reaction: styrene + O2 + NADH + H+ = NAD+ + styrene cis-glycol.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0256|EC:1.13.11.-									molecular_function											owl:Class	
GO:1990647	biolink:NamedThing	C/EBP complex	A dimeric, sequence specific DNA-binding transcription factor complex regulating the expression of genes involved in immune and inflammatory responses. Exists at least as alpha and beta homodimeric forms. Binds to regulatory regions of several acute-phase and cytokines genes and probably plays a role in the regulation of acute-phase reaction, inflammation and hemopoiesis. The consensus recognition site is 5'-T[TG]NNGNAA[TG]-3'. Transcription factor activity is inhibited by binding of CHOP forming heterodimers with alternative transcription factor activities.	tmpzr1t_l9r_go_relaxed.owl	C/EBPalpha complex|C/EBPbeta complex|C/EBP homodimer complex|C/EBPalpha homodimer complex|C/EBPbeta homodimer complex|C/EBP transcription factor complex					An example of this is Cebpa in rat (P05554) in PMID:8657121 (inferred from direct assay).		bhm	2015-02-19T11:00:09Z					cellular_component											owl:Class	
GO:0042382	biolink:NamedThing	paraspeckles	Discrete subnuclear bodies in the interchromatin nucleoplasmic space, often located adjacent to nuclear specks. 10-20 paraspeckles are typically found in human cell nuclei.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Paraspeckle									cellular_component											owl:Class	
GO:0009885	biolink:NamedThing	transmembrane histidine kinase cytokinin receptor activity	Combining with a cytokinin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: ATP + a protein-L-histidine = ADP + a protein-L-histidine phosphate.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0008801	biolink:NamedThing	beta-phosphoglucomutase activity	Catalysis of the reaction: beta-D-glucose 1-phosphate = beta-D-glucose 6-phosphate.	tmpzr1t_l9r_go_relaxed.owl	beta-D-glucose 1,6-phosphomutase activity				MetaCyc:BETA-PHOSPHOGLUCOMUTASE-RXN|RHEA:20113|KEGG_REACTION:R02728|EC:5.4.2.6									molecular_function											owl:Class	
GO:0050654	biolink:NamedThing	chondroitin sulfate proteoglycan metabolic process	The chemical reactions and pathways involving chondroitin sulfate proteoglycan, any glycoprotein whose glycosaminoglycan units are chondroitin sulfate. Chondroitin sulfates are a group of 10-60 kDa glycosaminoglycans, widely distributed in cartilage and other mammalian connective tissues; the repeat units consist of beta-(1,4)-linked D-glucuronyl beta-(1,3)-N-acetyl-D-galactosamine sulfate.	tmpzr1t_l9r_go_relaxed.owl	chondroitin sulphate proteoglycan metabolism|chondroitin sulphate proteoglycan metabolic process|chondroitin sulfate proteoglycan metabolism													biological_process											owl:Class	
GO:0003225	biolink:NamedThing	left ventricular trabecular myocardium morphogenesis	The process in which the anatomical structures of cardiac left ventricular trabecular myocardium are generated and organized.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-10-13T10:45:09Z					biological_process											owl:Class	
GO:0052168	biolink:NamedThing	modulation by symbiont of defense-related host calcium-dependent protein kinase pathway	Any process in which an organism modulates the frequency, rate or extent of the host calcium-dependent protein kinase signal transduction pathways during the host defense response. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	modulation by organism of defense-related calcium-dependent protein kinase pathway in other organism involved in symbiotic interaction|modulation by organism of defense-related host CDPK pathway											GO:0052307		biological_process											owl:Class	
GO:0008819	biolink:NamedThing	cobinamide kinase activity	Catalysis of the reaction: cobinamide + ATP = cobinamide phosphate + ADP. This reaction is the phosphorylation of the hydroxyl group of the 1-amino-2-propanol residue of cobinamide, in the presence of ATP, to form cobinamide phosphate.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0016992	biolink:NamedThing	lipoate synthase activity	Catalysis of the reaction: protein N6-(octanoyl)lysine + 2 sulfur + 2 S-adenosyl-L-methionine = protein N6-(lipoyl)lysine + 2 L-methionine + 2 5'-deoxyadenosyl.	tmpzr1t_l9r_go_relaxed.owl	lipoyl synthase activity|lipoic acid synthase|protein 6-N-(octanoyl)lysine:sulfur sulfurtransferase activity|LipA|LS|protein N6-(octanoyl)lysine:sulfur sulfurtransferase activity				Reactome:R-HSA-6793591|EC:2.8.1.8|MetaCyc:RXN0-949|RHEA:16585							GO:0017140		molecular_function											owl:Class	
GO:0010018	biolink:NamedThing	far-red light signaling pathway	The series of molecular signals initiated upon sensing of far red light by a photoreceptor molecule. Far red light is electromagnetic radiation of wavelength 700-800nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reversed by exposure to far red light. During the initial phase the phytochrome molecule is only present in the red light absorbing form, but on absorption of red light it changes to a far red light absorbing form, triggering progress through development. An immediate short period of exposure to far red light entirely returns the pigment to its initial state and prevents triggering of the developmental process. A thirty minute break between red and subsequent far red light exposure renders the red light effect irreversible, and development then occurs regardless of whether far red light exposure subsequently occurs.	tmpzr1t_l9r_go_relaxed.owl	far-red light signal transduction|far red light signalling pathway|far red signaling pathway													biological_process											owl:Class	
GO:0070337	biolink:NamedThing	3'-flap-structured DNA binding	Binding to a 3'-flap structure in DNA. A DNA flap structure is one in which a single-stranded 3'-end of DNA or RNA protrudes from a double-stranded DNA molecule.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0018095	biolink:NamedThing	protein polyglutamylation	The addition of one or more alpha-linked glutamyl units to the gamma carboxyl group of peptidyl-glutamic acid.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0202									biological_process											owl:Class	
GO:0072095	biolink:NamedThing	regulation of branch elongation involved in ureteric bud branching	Any process that modulates the frequency, rate or extent of branch elongation involved in ureteric bud branching, the growth of a branch of the ureteric bud along its axis.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-02-10T01:41:18Z					biological_process											owl:Class	
GO:0042329	biolink:NamedThing	structural constituent of collagen and cuticulin-based cuticle	The action of a molecule that contributes to the structural integrity of a collagen and cuticulin-based cuticle. An example of this process is found in Caenorhabditis elegans.	tmpzr1t_l9r_go_relaxed.owl	structural constituent of cuticle													molecular_function											owl:Class	
GO:0045515	biolink:NamedThing	interleukin-18 receptor binding	Binding to an interleukin-18 receptor.	tmpzr1t_l9r_go_relaxed.owl	interleukin-18 receptor ligand|IL-18													molecular_function											owl:Class	
GO:0034297	biolink:NamedThing	oidium formation	The process in which oidia, a type of asexual spore found in fungi, are formed. Oidia are borne a few at a time on very simple hyphae that protrude a short distance into the substrate, and are usually presumed not to constitute the main reproductive strategy of the fungus.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1990976	biolink:NamedThing	protein transport along microtubule to mitotic spindle pole body	The directed movement of a protein along a microtubule to the mitotic spindle pole body, mediated by motor proteins.	tmpzr1t_l9r_go_relaxed.owl								vw	2016-06-30T13:09:08Z					biological_process											owl:Class	
GO:0003328	biolink:NamedThing	pancreatic D cell fate commitment	The commitment of a cell to a pancreatic D cell fate and its capacity to differentiate into a pancreatic D cell. A delta cell is a cell of the pancreas that produces somatostatin.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-11-02T08:33:36Z					biological_process											owl:Class	
GO:0071909	biolink:NamedThing	determination of stomach left/right asymmetry	Determination of the asymmetric location of the stomach with respect to the left and right halves of the organism.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-09-22T10:25:30Z					biological_process											owl:Class	
GO:0046918	biolink:NamedThing	N-terminal peptidyl-glycine N-palmitoylation	The covalent attachment of a palmitoyl group to a nitrogen (N) atom in an N-terminal glycine residue to form N-palmitoyl-glycine.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0339	Palmitoylation of glycine only occurs when glycine is at the N-terminal position of a protein.								biological_process											owl:Class	
GO:0071542	biolink:NamedThing	dopaminergic neuron differentiation	The process in which a neuroblast acquires the specialized structural and functional features of a dopaminergic neuron, a neuron that secretes dopamine.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-01-12T02:28:44Z					biological_process											owl:Class	
GO:0006207	biolink:NamedThing	'de novo' pyrimidine nucleobase biosynthetic process	The chemical reactions and pathways resulting in the formation of pyrimidine nucleobases, 1,3-diazine, organic nitrogenous bases, beginning with the synthesis of a pyrimidine ring from simpler precursors.	tmpzr1t_l9r_go_relaxed.owl	'de novo' pyrimidine base formation|'de novo' pyrimidine base biosynthetic process|'de novo' pyrimidine base anabolism|'de novo' pyrimidine base synthesis|'de novo' pyrimidine base biosynthesis													biological_process											owl:Class	
GO:0106235	biolink:NamedThing	ceramide-1-phosphate phosphatase activity	Catalysis of the reaction: ceramide-1-phosphate + H2O = ceramide+ phosphate.	tmpzr1t_l9r_go_relaxed.owl					RHEA:50888			hjd	2019-11-21T20:40:39Z					molecular_function											owl:Class	
GO:0042577	biolink:NamedThing	lipid phosphatase activity	Catalysis of the reaction: a phospholipid + H2O = a lipid + phosphate.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1904843	biolink:NamedThing	cellular response to nitroglycerin	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitroglycerin stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to nitroglycerine|cellular response to nitroglycerol|cellular response to trinitroglycerol|cellular response to trinitroglycerin							sl	2015-12-07T18:30:55Z					biological_process											owl:Class	
GO:1904198	biolink:NamedThing	negative regulation of regulation of vascular associated smooth muscle cell membrane depolarization	Any process that stops, prevents or reduces the frequency, rate or extent of regulation of vascular smooth muscle cell membrane depolarization.	tmpzr1t_l9r_go_relaxed.owl	down regulation of regulation of vascular smooth muscle cell membrane depolarization|inhibition of regulation of vascular smooth muscle cell membrane depolarization|down-regulation of regulation of vascular smooth muscle cell membrane depolarization|negative regulation of regulation of vascular smooth muscle cell membrane depolarization|downregulation of regulation of vascular smooth muscle cell membrane depolarization							sl	2015-05-07T17:16:44Z					biological_process											owl:Class	
GO:0008812	biolink:NamedThing	choline dehydrogenase activity	Catalysis of the reaction: A + choline = AH(2) + betaine aldehyde.	tmpzr1t_l9r_go_relaxed.owl	choline:acceptor 1-oxidoreductase activity|choline oxidase activity|choline:(acceptor) 1-oxidoreductase activity|choline:(acceptor) oxidoreductase activity|choline-cytochrome c reductase activity				Reactome:R-HSA-6797961|RHEA:17433|EC:1.1.99.1|KEGG_REACTION:R01025|MetaCyc:CHD-RXN									molecular_function											owl:Class	
GO:0009979	biolink:NamedThing	16:0 monogalactosyldiacylglycerol desaturase activity	Catalysis of the introduction of an omega-3 double bond into an unsaturated 16-carbon fatty acid in a monogalactosyldiacylglycerol molecule.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0042389	biolink:NamedThing	omega-3 fatty acid desaturase activity	Catalysis of the introduction of an omega-3 double bond into the fatty acid hydrocarbon chain.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0003949	biolink:NamedThing	1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase activity	Catalysis of the reaction: 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide = 5-[(5-phospho-1-deoxy-D-ribulos-1-ylimino)methylamino]-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide.	tmpzr1t_l9r_go_relaxed.owl	1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide aldose-ketose-isomerase activity|1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide ketol-isomerase activity|phosphoribosylformiminoaminophosphoribosylimidazolecarboxamide isomerase activity|N-(phosphoribosylformimino) aminophosphoribosylimidazolecarboxamide isomerase activity|phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase activity|N-(5'-phospho-D-ribosylformimino)-5-amino-1-(5''-phosphoribosyl)-4-imidazolecarboxamide isomerase activity				MetaCyc:PRIBFAICARPISOM-RXN|EC:5.3.1.16|RHEA:15469|KEGG_REACTION:R04640									molecular_function											owl:Class	
GO:0060982	biolink:NamedThing	coronary artery morphogenesis	The process in which the anatomical structures of coronary arteries are generated and organized. Coronary arteries are blood vessels that transport blood to the heart muscle.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-10-06T02:58:52Z					biological_process											owl:Class	
GO:0047157	biolink:NamedThing	myelin-proteolipid O-palmitoyltransferase activity	Catalysis of the reaction: [myelin proteolipid] + palmityl-CoA = [myelin proteolipid] O-palmitoylprotein + CoA.	tmpzr1t_l9r_go_relaxed.owl	myelin PLP acyltransferase activity|[myelin-proteolipid] O-palmitoyltransferase activity|acyl-protein synthase activity|palmitoyl-CoA:[myelin-proteolipid] O-palmitoyltransferase activity	https://github.com/geneontology/go-ontology/issues/21319			EC:2.3.1.100|MetaCyc:2.3.1.100-RXN									molecular_function											owl:Class	
GO:0010367	biolink:NamedThing	extracellular isoamylase complex	A protein complex whose composition varies amongst species; in rice it probably exists in a homo-tetramer to homo-hexamer form and in Gram negative bacteria as a dimer. Functions in the hydrolysis of alpha-(1,6)-D-glucosidic branch linkages. Isoamylases in animals are localized in the extracellular space.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0047730	biolink:NamedThing	carnosine synthase activity	Catalysis of the reaction: ATP + L-histidine + beta-alanine = AMP + diphosphate + carnosine.	tmpzr1t_l9r_go_relaxed.owl	carnosine-homocarnosine synthetase activity|L-histidine:beta-alanine ligase (AMP-forming)|carnosine synthetase activity|homocarnosine-carnosine synthetase activity|carnosine-anserine synthetase activity				MetaCyc:CARNOSINE-SYNTHASE-RXN|EC:6.3.2.11|Reactome:R-HSA-6786245|RHEA:19297									molecular_function											owl:Class	
GO:0006785	biolink:NamedThing	heme B biosynthetic process	The chemical reactions and pathways resulting in the formation of heme B, a Fe(II) porphyrin complex readily isolated from the hemoglobin of beef blood, but also found in other proteins including other hemoglobins, myoglobins, cytochromes P-450, catalases, peroxidases as well as b type cytochromes.	tmpzr1t_l9r_go_relaxed.owl	heme B synthesis|protoheme biosynthesis|heme B biosynthesis|heme B anabolism|heme B formation|protoheme biosynthetic process|haem B biosynthesis|haem B biosynthetic process													biological_process											owl:Class	
GO:1990328	biolink:NamedThing	RPB4-RPB7 complex	A protein complex that cycles between the nucleus where it is part of the RNA polymerase II and the cytoplasmic mRNA processing body where it mediates the two major cytoplasmic mRNA decay pathways.	tmpzr1t_l9r_go_relaxed.owl	RNA polymerase II, RPB4-RPB7 subcomplex	https://github.com/geneontology/go-ontology/issues/10931						bhm	2014-03-17T09:37:07Z					cellular_component											owl:Class	
GO:0061055	biolink:NamedThing	myotome development	The progression of the myotome over time, from its formation to the mature structure. The myotome is the portion of the somite that will give rise to muscle.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-03-02T12:11:01Z					biological_process											owl:Class	
GO:0000703	biolink:NamedThing	oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity	Catalysis of the removal oxidized pyrimidine bases by cleaving the N-C1' glycosidic bond between the oxidized pyrimidine and the deoxyribose sugar. The reaction involves formation of a covalent enzyme-pyrimidine base intermediate. Release of the enzyme and free base by a beta-elimination or a beta, gamma-elimination mechanism results in the cleavage of the DNA backbone 3' of the apyrimidinic (AP) site.	tmpzr1t_l9r_go_relaxed.owl	pyrimidine-specific oxidized base lesion DNA N-glycosylase activity|endonuclease III|oxidized pyrimidine base lesion DNA N-glycosylase activity|DNA glycosylase/beta-lyase|bifunctional DNA glycosylase|endodeoxyribonuclease III|endonuclease VIII activity|DNA glycosylase/AP-lyase				Reactome:R-HSA-110227|Reactome:R-HSA-110226|Reactome:R-HSA-110224	Consider also annotating to the molecular function term 'DNA-(apurinic or apyrimidinic site) lyase activity ; GO:0003906'.						GO:0019004		molecular_function											owl:Class	
GO:0010349	biolink:NamedThing	L-galactose dehydrogenase activity	Catalysis of the reaction: L-galactose + NAD+ = L-galactono-1,4-lactone + NADH + H+.	tmpzr1t_l9r_go_relaxed.owl	L-galactose 1-dehydrogenase activity	https://github.com/geneontology/go-ontology/issues/21831|https://github.com/geneontology/go-ontology/issues/3975			MetaCyc:RXN-1884|EC:1.1.1.316|RHEA:31559									molecular_function											owl:Class	
GO:0140208	biolink:NamedThing	apoptotic process in response to mitochondrial fragmentation	Any apoptotic process that occurs as a result of mitochondrial fragmentation.	tmpzr1t_l9r_go_relaxed.owl	apoptosis in response to mitochondrial fragmentation							pg	2018-03-08T16:54:17Z					biological_process											owl:Class	
GO:1901499	biolink:NamedThing	response to hexane	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hexane stimulus.	tmpzr1t_l9r_go_relaxed.owl								tt	2012-10-16T15:14:49Z					biological_process											owl:Class	
GO:0034690	biolink:NamedThing	integrin alphaD-beta2 complex	An integrin complex that comprises one alphaD subunit and one beta2 subunit.	tmpzr1t_l9r_go_relaxed.owl	Itgad-Itgb2 complex|alphaD-beta2 integrin complex													cellular_component											owl:Class	
GO:0018727	biolink:NamedThing	2-phenanthrol sulfotransferase activity	Catalysis of the reaction: 2-phenanthrol + X-SO3(-) = HX + 2-phenanthrylsulfate.	tmpzr1t_l9r_go_relaxed.owl	2-phenanthrol sulphotransferase activity				UM-BBD_reactionID:r0563									molecular_function											owl:Class	
GO:0010583	biolink:NamedThing	response to cyclopentenone	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cyclopentenone stimulus. Cyclopentenones are oxylipins derived from polyunsaturated fatty acids. They are structurally similar to jasmonic acid, but contain a reactive unsaturated carbonyl structure in the cyclo-ring. Cyclopentenones include phytoprostanes and 12-oxo-phytodienoic acid.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1902286	biolink:NamedThing	semaphorin-plexin signaling pathway involved in dendrite guidance	Any semaphorin-plexin signaling pathway that is involved in dendrite guidance.	tmpzr1t_l9r_go_relaxed.owl	semaphorin-plexin signaling pathway involved in dendritic guidance|semaphorin-plexin signalling pathway involved in dendritic guidance|semaphorin-plexin signalling pathway involved in dendrite guidance							pr	2013-07-08T16:06:55Z					biological_process											owl:Class	
GO:0097593	biolink:NamedThing	ventral disc microtubule array	A part of the ventral disc of Giardia species (trophozoite stage) consisting of a spiral array of microtubules linked to the ventral membrane. These microtubules form the base of the ventral disc dorsal microribbons that extend nearly perpendicular from the membrane.	tmpzr1t_l9r_go_relaxed.owl	ventral disc spiral microtubule array|ventral disk microtubule array|spiral microtubule array					Due to the asymmetric nature of the Giardia trophozoite, this term is defined spatially as the trophozoite is viewed from the dorsal side, with the two nuclei dorsal to the ventral disc, and the ventral disc toward the anterior.		pr	2014-04-03T11:17:17Z					cellular_component											owl:Class	
GO:0005582	biolink:NamedThing	collagen type XV trimer	A collagen homotrimer of alpha1(XV) chains; a chondroitin sulfate proteoglycan often found in specialized basement membranes where it bridges between fibrils.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0070709	biolink:NamedThing	RNA guanosine insertion	The modification of an RNA molecule by insertion of a guanosine nucleotide.	tmpzr1t_l9r_go_relaxed.owl	RNA G insertion							mah	2009-06-08T04:57:26Z					biological_process											owl:Class	
GO:0061945	biolink:NamedThing	regulation of protein K48-linked ubiquitination	Any process that modulates the rate, frequency or extent of protein K-48-linked ubiquitination, a protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 48 of the ubiquitin monomers, is added to a protein. K48-linked ubiquitination targets the substrate protein for degradation.	tmpzr1t_l9r_go_relaxed.owl								dph	2017-09-22T11:45:43Z					biological_process											owl:Class	
GO:0062205	biolink:NamedThing	miltiradiene synthase activity	Catalysis of the reaction: (+)-copalyl diphosphate = diphosphate + miltiradiene.	tmpzr1t_l9r_go_relaxed.owl	multiradiene synthase activity				MetaCyc:RXN-13338|EC:4.2.3.131|RHEA:33983			dph	2020-01-03T14:05:49Z			GO:0102353		molecular_function											owl:Class	
GO:0031830	biolink:NamedThing	type 5A serotonin receptor binding	Binding to a type 5A serotonin receptor.	tmpzr1t_l9r_go_relaxed.owl	5-hydroxytryptamine 5A receptor binding|type 5A serotonin receptor ligand													molecular_function											owl:Class	
GO:0071549	biolink:NamedThing	cellular response to dexamethasone stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dexamethasone stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-01-13T01:24:49Z					biological_process											owl:Class	
GO:0048170	biolink:NamedThing	positive regulation of long-term neuronal synaptic plasticity	A process that increases long-term neuronal synaptic plasticity, the ability of neuronal synapses to change long-term as circumstances require. Long-term neuronal synaptic plasticity generally involves increase or decrease in actual synapse numbers.	tmpzr1t_l9r_go_relaxed.owl	up regulation of long-term neuronal synaptic plasticity|up-regulation of long-term neuronal synaptic plasticity|activation of long-term neuronal synaptic plasticity|stimulation of long-term neuronal synaptic plasticity|upregulation of long-term neuronal synaptic plasticity					Note that the syntax of the definition of this term is different from the usual regulation syntax because it describes regulation of a trait rather than regulation of a process.								biological_process											owl:Class	
GO:0098505	biolink:NamedThing	G-rich strand telomeric DNA binding	Binding to G-rich, single-stranded, telomere-associated DNA.	tmpzr1t_l9r_go_relaxed.owl								dos	2013-09-23T13:16:24Z					molecular_function											owl:Class	
GO:0070766	biolink:NamedThing	endobrevin-synaptobrevin 2-alpha-SNAP-NSF-syntaxin-4 complex	A SNARE complex that contains endobrevin (VAMP8), synaptobrevin 2 (VAMP2), alpha-SNAP, NSF, and syntaxin 4 (or orthologs thereof).	tmpzr1t_l9r_go_relaxed.owl	Stx4-Napa-Vamp3-Nsf-Vamp2 complex|SNARE complex (Stx4, Napa, Vamp3, Nsf, Vamp2)							mah	2009-06-29T04:41:55Z					cellular_component											owl:Class	
GO:0034633	biolink:NamedThing	retinol transport	The directed movement of retinol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Retinol is vitamin A1, 2,6,6-trimethyl-1-(9'-hydroxy-3',7'-dimethylnona-1',3',5',7'-tetraenyl)cyclohex-1-ene, one of the three components that makes up vitamin A.	tmpzr1t_l9r_go_relaxed.owl	vitamin A1 transport													biological_process											owl:Class	
GO:0035093	biolink:NamedThing	spermatogenesis, exchange of chromosomal proteins	The replacement of somatic histones within sperm chromatin with sperm-specific histones or protamines with unique DNA-binding properties, resulting in condensation of the sperm chromatin.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/22255												biological_process											owl:Class	
GO:0140301	biolink:NamedThing	pollen-stigma interaction	The interactions (or cell to cell communication) that occur between the pollen grain (male gametophyte) and the stigmatic tissues of the female sporophyte after the pollen reaches the stigmatic papillae.	tmpzr1t_l9r_go_relaxed.owl								pg	2019-02-22T13:58:21Z					biological_process											owl:Class	
GO:0098846	biolink:NamedThing	podocyte foot	A cell projection of a podocyte (glomerular visceral epithelial cell) forming a foot-like structure projecting from a podocyte primary projection, that wraps around capillaries of a renal glomerulus. Adjacent feet (pedicels) interdigitate, leaving thin filtration slits between them, which are covered by slit diaphragms.	tmpzr1t_l9r_go_relaxed.owl	secondary podocyte projection|pedicel|podocyte foot process				Wikipedia:Podocyte									cellular_component											owl:Class	
GO:0014031	biolink:NamedThing	mesenchymal cell development	The process aimed at the progression of a mesenchymal cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0051525	biolink:NamedThing	NFAT protein binding	Binding to NFAT (nuclear factor of activated T cells) proteins, a family of transcription factors. NFAT proteins have crucial roles in the development and function of the immune system.	tmpzr1t_l9r_go_relaxed.owl	NFATx binding|NFATc4 binding|non-calcium-regulated NFAT protein binding|NFATc2 binding|NFATc binding|NFAT3 protein binding|NFAT2 protein binding|NFAT4 protein binding|NFATp binding|NFAT1 protein binding|nuclear factor of activated T cell protein binding|NFATc1 binding|NFAT binding|NFAT5 protein binding|NFATc3 binding											GO:0051526|GO:0051529|GO:0051527|GO:0051530|GO:0051528		molecular_function											owl:Class	
GO:0051433	biolink:NamedThing	BH2 domain binding	Binding to a BH2 protein domain, present in Bcl-2 family members. Proteins that act as inhibitors of apoptosis harbour at least three BH domains: BH1, BH2 and BH3; the BH1 and BH2 domains are found in all death antagonists of the Bcl-2 family but only in one class of death agonists.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0046036	biolink:NamedThing	CTP metabolic process	The chemical reactions and pathways involving CTP, cytidine triphosphate.	tmpzr1t_l9r_go_relaxed.owl	CTP metabolism|CTP deamination											GO:0006243		biological_process											owl:Class	
GO:0048528	biolink:NamedThing	post-embryonic root development	The process whose specific outcome is the progression of the post-embryonic root over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0018008	biolink:NamedThing	N-terminal peptidyl-glycine N-myristoylation	The myristoylation of the N-terminal glycine of proteins to form the derivative N-myristoyl-glycine.	tmpzr1t_l9r_go_relaxed.owl	N-terminal peptidyl-glycine N-myristylation				RESID:AA0059									biological_process											owl:Class	
GO:0140625	biolink:NamedThing	opioid growth factor receptor activity	Combining with the opioid growth factor (OGF, met-enkephalin) and transmitting the signal across the nuclear membrane. Met-enkephalin is an endogenous opioid peptide that binds to opioid and opioid growth factor receptors, regulating tissue growth in a variety of cellular processes.	tmpzr1t_l9r_go_relaxed.owl	methionine enkephalin receptor activity|metenkefalin receptor activity|met-enkephalin receptor activity	https://github.com/geneontology/go-ontology/issues/21110						pg	2021-03-17T13:15:33Z					molecular_function											owl:Class	
GO:0006211	biolink:NamedThing	5-methylcytosine catabolic process	The chemical reactions and pathways resulting in the breakdown of 5-methylcytosine, a methylated base of DNA.	tmpzr1t_l9r_go_relaxed.owl	5-methylcytosine breakdown|5-methylcytosine catabolism|5-methylcytosine degradation													biological_process											owl:Class	
GO:1903563	biolink:NamedThing	microtubule bundle formation involved in horsetail-astral microtubule organization	Any microtubule bundle formation that is involved in horsetail-astral microtubule organization.	tmpzr1t_l9r_go_relaxed.owl	microtubule bundling involved in horsetail-astral microtubule organisation|microtubule bundling involved in horsetail-astral microtubule organization|microtubule bundle formation involved in horsetail-astral microtubule organisation|microtubule bundle formation involved in horsetail-astral microtubule array organization|microtubule bundling involved in horsetail-astral microtubule array organization							vw	2014-10-23T11:06:35Z					biological_process											owl:Class	
GO:0009538	biolink:NamedThing	photosystem I reaction center	A photochemical system containing P700, the chlorophyll a dimer that functions as a primary electron donor. Functioning as a light-dependent plastocyanin-ferredoxin oxidoreductase, it transfers electrons from plastocyanin to ferredoxin.	tmpzr1t_l9r_go_relaxed.owl	photosystem I reaction centre													cellular_component											owl:Class	
GO:0052662	biolink:NamedThing	zeaxanthin epoxidase activity	Catalysis of the reaction:  all-trans-zeaxanthin + 4 H+ + 2 O2 + 4 reduced [2Fe-2S]-[ferredoxin] = all-trans-violaxanthin + 2 H2O + 4 oxidized [2Fe-2S]-[ferredoxin].	tmpzr1t_l9r_go_relaxed.owl	zeaxanthin epoxidase [overall] activity|antheraxanthin epoxidase activity|zea-epoxidase activity	https://github.com/geneontology/go-ontology/issues/21412			KEGG_REACTION:R06947|KEGG_REACTION:R07200|KEGG_REACTION:R07199|EC:1.14.15.21|MetaCyc:RXN-7979|MetaCyc:RXN-7978|KEGG_REACTION:R06946|RHEA:24084	Multi-step reaction: RHEA:14937 and RHEA:24084. Formerly EC:1.14.13.90.						GO:0052663|GO:0009540		molecular_function											owl:Class	
GO:0004530	biolink:NamedThing	deoxyribonuclease I activity	Catalysis of the endonucleolytic cleavage of DNA to 5'-phosphodinucleotide and 5'-phosphooligonucleotide end products.	tmpzr1t_l9r_go_relaxed.owl	DNase I|thymonuclease, dornase activity|thymonuclease activity|pancreatic deoxyribonuclease|pancreatic dornase|dornava|Escherichia coli endonuclease I|DNA endonuclease activity|DNase activity|deoxyribonuclease A|DNA nuclease activity|endodeoxyribonuclease I|deoxyribonuclease (pancreatic)|pancreatic DNase activity|DNAase activity|deoxyribonucleic phosphatase activity|dornavac|DNA depolymerase activity|alkaline deoxyribonuclease activity|alkaline DNase activity				EC:3.1.21.1|MetaCyc:3.1.21.1-RXN									molecular_function											owl:Class	
GO:0007546	biolink:NamedThing	somatic processes downstream of sex determination signal	The events determining the somatic sexual phenotype after the initial transmission of that phenotype to soma-specific information pathways.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0032482	biolink:NamedThing	Rab protein signal transduction	A series of molecular signals within the cell that are mediated by a member of the Rab family of proteins switching to a GTP-bound active state.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0033401	biolink:NamedThing	UUU codon-amino acid adaptor activity	A triplet codon-amino acid adaptor activity that recognizes a UUU codon.	tmpzr1t_l9r_go_relaxed.owl	phenylalanine tRNA|TTT codon-amino acid adaptor activity					Note that in the standard genetic code, TTT codes for phenylalanine.								molecular_function											owl:Class	
GO:1990909	biolink:NamedThing	Wnt signalosome	A multiprotein protein complex containing membrane-localized Wnt receptors and cytosolic protein complexes, which is capable of transmitting the Wnt signal. Contains at least a Wnt protein, LRP5 or LRP6, a member of the Frizzled (Fz) family, Axin and and a Dishevelled (DVL) protein.	tmpzr1t_l9r_go_relaxed.owl	Wnt-LRP5/6 signalosome|LRP5/6 signalosome|Wnt signalosome complex|LRP6 signalosome					Within the Wnt signalosome, beta-catenin phosphorylation is inhibited through internalization of the signalosome complex, resulting in the sequestration of GSK3-beta into multi-vesicular bodies. No longer phosphorylated and targeted for degradation, beta-catenin is free to enter the nucleus and modulate downstream transcription.		bf	2015-12-07T14:04:23Z					cellular_component											owl:Class	
GO:0097420	biolink:NamedThing	skein-like inclusion	Intracytoplasmic filamentous structure frequently encountered in preparations immunostained for ubiquitin.	tmpzr1t_l9r_go_relaxed.owl					NIF_Subcellular:nlx_subcell_20090103			pr	2012-11-06T20:58:35Z					cellular_component											owl:Class	
GO:0016664	biolink:NamedThing	oxidoreductase activity, acting on other nitrogenous compounds as donors, iron-sulfur protein as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which a nitrogenous group, excluding NH and NH2 groups, acts as a hydrogen or electron donor and reduces an iron-sulfur protein.	tmpzr1t_l9r_go_relaxed.owl	oxidoreductase activity, acting on other nitrogenous compounds as donors, iron-sulphur protein as acceptor				EC:1.7.7.-									molecular_function											owl:Class	
GO:1904428	biolink:NamedThing	negative regulation of tubulin deacetylation	Any process that stops, prevents or reduces the frequency, rate or extent of tubulin deacetylation.	tmpzr1t_l9r_go_relaxed.owl	inhibition of tubulin deacetylation|down regulation of tubulin deacetylation|downregulation of tubulin deacetylation|down-regulation of tubulin deacetylation							sart	2015-07-03T14:42:58Z					biological_process											owl:Class	
GO:0021606	biolink:NamedThing	accessory nerve maturation	A developmental process, independent of morphogenetic (shape) change, that is required for the accessory nerve to attain its fully functional state. The spinal branch of this motor nerve innervates the trapezius and the sternocleidomastoid muscles. The cranial branch joins the vagus nerve and innervates the same targets as the vagus nerve.	tmpzr1t_l9r_go_relaxed.owl	CN XI maturation|spinal accessory nerve maturation													biological_process											owl:Class	
GO:0039683	biolink:NamedThing	rolling circle double-stranded viral DNA replication	A rolling circle viral DNA replication that begins with a double-stranded viral DNA genome.	tmpzr1t_l9r_go_relaxed.owl	dsDNA rolling circle replication				VZ:2676			bf	2013-10-17T14:15:04Z					biological_process											owl:Class	
GO:0072494	biolink:NamedThing	host multivesicular body	A late endosome in which regions of the limiting host cell endosomal membrane invaginate to form internal vesicles; host membrane proteins that enter the internal vesicles are sequestered from the host cytoplasm.	tmpzr1t_l9r_go_relaxed.owl	host cell multivesicular body							mah	2010-12-15T11:48:39Z					cellular_component											owl:Class	
GO:0034809	biolink:NamedThing	benzo(a)pyrene-cis-4,5-dihydrodiol dehydrogenase activity	Catalysis of the reaction: benzo(a)pyrene-cis-4,5-dihydrodiol = 4,5-dihydroxybenzo(a)pyrene + H2.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r1127									molecular_function											owl:Class	
GO:0042818	biolink:NamedThing	pyridoxamine metabolic process	The chemical reactions and pathways involving 4-(aminomethyl)-5-(hydroxymethyl)-2-methylpyridin-3-ol, one of the vitamin B6 compounds. Pyridoxal, pyridoxamine and pyridoxine are collectively known as vitamin B6, and are efficiently converted to the biologically active form of vitamin B6, pyridoxal phosphate.	tmpzr1t_l9r_go_relaxed.owl	pyridoxamine metabolism													biological_process											owl:Class	
GO:0070843	biolink:NamedThing	misfolded protein transport	The directed movement of misfolded proteins in a cell, including the movement of proteins between specific compartments or structures within a cell.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-07-31T12:50:00Z					biological_process											owl:Class	
GO:0047516	biolink:NamedThing	1,3-propanediol dehydrogenase activity	Catalysis of the reaction: propane-1,3-diol + NAD+ = 3-hydroxypropanal + NADH + H+.	tmpzr1t_l9r_go_relaxed.owl	1,3-PD:NAD+ oxidoreductase activity|3-hydroxypropionaldehyde reductase activity|propane-1,3-diol:NAD+ 1-oxidoreductase activity|1,3-propanediol oxidoreductase activity|1,3-propanediol:NAD+ oxidoreductase activity				EC:1.1.1.202|MetaCyc:13-PROPANEDIOL-DEHYDROGENASE-RXN|RHEA:23188									molecular_function											owl:Class	
GO:0120154	biolink:NamedThing	negative regulation of ERBB4 signaling pathway	Any process that stops, prevents or reduces the frequency, rate or extent of ERBB4 signaling pathway.	tmpzr1t_l9r_go_relaxed.owl								krc	2018-05-01T17:12:23Z					biological_process											owl:Class	
GO:0043015	biolink:NamedThing	gamma-tubulin binding	Binding to the microtubule constituent protein gamma-tubulin.	tmpzr1t_l9r_go_relaxed.owl	gamma tubulin binding													molecular_function											owl:Class	
GO:0034458	biolink:NamedThing	3'-5' RNA helicase activity	Unwinding of an RNA helix in the 3' to 5' direction, driven by ATP hydrolysis.	tmpzr1t_l9r_go_relaxed.owl	3' to 5' RNA helicase activity|ATP-dependent 3' to 5' RNA helicase activity|ATP-dependent 3'-5' RNA helicase activity	https://github.com/geneontology/go-ontology/issues/21612										GO:0034459		molecular_function											owl:Class	
GO:0038170	biolink:NamedThing	somatostatin signaling pathway	The series of molecular signals generated as a consequence of the peptide somatostatin (SST) binding to a somatostatin receptor (SSTR). The pathway proceeds with the receptor transmitting the signal to a heterotrimeric G-protein complex and ends with regulation of a downstream cellular process, e.g. transcription.	tmpzr1t_l9r_go_relaxed.owl	somatostatin signalling pathway|somatotrophin release inhibiting factor signaling pathway|SST signaling pathway|SRIF signaling pathway|somatostatin-activated somatostatin receptor signaling pathway|somatostatin-mediated signaling pathway							bf	2012-06-12T10:33:21Z					biological_process											owl:Class	
GO:0038169	biolink:NamedThing	somatostatin receptor signaling pathway	The series of molecular signals generated as a consequence of a somatostatin receptor (SSTR) binding to one of its physiological ligands and transmitting the signal to a heterotrimeric G-protein complex. The pathway ends with regulation of a downstream cellular process, e.g. transcription.	tmpzr1t_l9r_go_relaxed.owl	SSTR signaling pathway|SST receptor signaling pathway					In addition to somatostatin (SST), the somatostatin receptors (SSTRs) can also be activated by the agonist cortistatin (CST). For signal transduction specifically initiated by the ligand somatostatin, consider instead annotating to the child term 'somatostatin signaling pathway ; GO:0038170'.		bf	2012-06-12T10:30:01Z					biological_process											owl:Class	
GO:0039530	biolink:NamedThing	MDA-5 signaling pathway	Any series of molecular signals generated as a consequence of the cytoplasmic pattern recognition receptor (PRR) MDA-5 (also known as IFIH1) binding to viral RNA. MDA-5 detects RNA synthesized during active viral replication and triggers a signaling pathway to protect the host against viral infection, for example by inducing the expression of antiviral cytokines.	tmpzr1t_l9r_go_relaxed.owl	MDA5 signaling pathway|MDA-5 signalling pathway|melanoma differentiation-associated gene 5 signaling pathway|IFIH1 signaling pathway							bf	2011-12-20T03:14:52Z					biological_process											owl:Class	
GO:0000493	biolink:NamedThing	box H/ACA snoRNP assembly	The aggregation, arrangement and bonding together of proteins and a box H/ACA snoRNA to form a box H/ACA small nucleolar ribonucleoprotein (snoRNP) complex.	tmpzr1t_l9r_go_relaxed.owl	box H/ACA small nucleolar ribonucleoprotein complex assembly													biological_process											owl:Class	
GO:0034925	biolink:NamedThing	pyrene 4,5-monooxygenase activity	Catalysis of the reaction: pyrene + O2 + 2 H+ + 2 e- = pyrene-4,5-oxide + H2O.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0941									molecular_function											owl:Class	
GO:0008114	biolink:NamedThing	phosphogluconate 2-dehydrogenase activity	Catalysis of the reaction: 6-phospho-D-gluconate + NADP+ = 6-phospho-2-dehydro-D-gluconate + NADPH.	tmpzr1t_l9r_go_relaxed.owl	phosphogluconate dehydrogenase activity|6-phosphogluconate dehydrogenase (NAD)|gluconate 6-phosphate dehydrogenase activity|6-phosphogluconate 2-dehydrogenase activity|6-phospho-D-gluconate:NAD(P)+ 2-oxidoreductase activity|6-phosphogluconic dehydrogenase activity|2-keto-6-phosphogluconate reductase activity				EC:1.1.1.43|MetaCyc:1.1.1.43-RXN									molecular_function											owl:Class	
GO:0036216	biolink:NamedThing	cellular response to stem cell factor stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stem cell factor (SCF) stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to KITLG|cellular response to KIT ligand|cellular response to SCF|cellular response to hematopoietic growth factor KL							bf	2012-04-27T10:30:53Z					biological_process											owl:Class	
GO:2000099	biolink:NamedThing	regulation of establishment or maintenance of bipolar cell polarity	Any process that modulates the frequency, rate or extent of establishment or maintenance of bipolar cell polarity.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-09-14T04:40:51Z					biological_process											owl:Class	
GO:0030741	biolink:NamedThing	inositol 1-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine(1+) + myo-inositol = 1D-1-O-methyl-myo-inositol + S-adenosyl-L-homocysteine + H(+).	tmpzr1t_l9r_go_relaxed.owl	inositol 3-O-methyltransferase activity|inositol 3-O-methyltransferase (name based on 1L-numbering system and not 1D-numbering)|S-adenosylmethionine:myo-inositol 3-methyltransferase activity|myo-inositol 3-O-methyltransferase activity|S-adenosyl-L-methionine:myo-inositol 3-O-methyltransferase activity|inositol D-1-methyltransferase activity|S-adenosyl-L-methionine:1D-myo-inositol 1-O-methyltransferase activity				KEGG_REACTION:R01188|EC:2.1.1.40|MetaCyc:MYO-INOSITOL-3-O-METHYLTRANSFERASE-RXN|RHEA:17565									molecular_function											owl:Class	
GO:0052792	biolink:NamedThing	endo-xylogalacturonan hydrolase activity	Catalysis of the endohydrolysis of xylogalacturonate by cleavage of the alpha-(1,4)-linkage. Xylogalacturonate (XGA) is composed of a chain of alpha-(1,4)-linked D-galacturonic acid residues with beta-D-xylose substituted at the O3 position.	tmpzr1t_l9r_go_relaxed.owl	endo-galacturonase activity							ai	2011-10-05T03:57:30Z					molecular_function											owl:Class	
GO:0052813	biolink:NamedThing	phosphatidylinositol bisphosphate kinase activity	Catalysis of the reaction: ATP + a phosphatidylinositol bisphosphate = ADP + a phosphatidylinositol trisphosphate.	tmpzr1t_l9r_go_relaxed.owl								ai	2011-10-21T03:55:36Z					molecular_function											owl:Class	
GO:0030554	biolink:NamedThing	adenyl nucleotide binding	Binding to an adenyl nucleotide, an adenosine esterified with (ortho)phosphate.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0061857	biolink:NamedThing	endoplasmic reticulum stress-induced pre-emptive quality control	The response to endoplasimic reticulum stress in which nascent proteins are degraded by attenuation of their translocation into the ER followed by rerouting to the cytosol without cleavage of the signal peptide, and subsequent degradation by the proteasome.	tmpzr1t_l9r_go_relaxed.owl	ER pQC|ER stress-indiced pre-emptive quality control							dph	2017-03-28T13:05:03Z					biological_process											owl:Class	
GO:0030287	biolink:NamedThing	cell wall-bounded periplasmic space	The region between the plasma membrane and the cell wall in organisms lacking an outer cell membrane such as yeast and Gram positive bacteria. The region is thinner than the equivalent in Gram negative bacteria.	tmpzr1t_l9r_go_relaxed.owl	cell wall-enclosed periplasmic space|IWZ|inner wall zone|cell wall bounded periplasmic space													cellular_component											owl:Class	
GO:0052675	biolink:NamedThing	3-methylbutanol:NADP oxidoreductase activity	Catalysis of the reaction: 3-methylbutanol + NADP+ = 3-methylbutanal + NADPH + H+. 3-methylbutanal is also known as isovaleraldehyde.	tmpzr1t_l9r_go_relaxed.owl	3-methylbutanol:NADP+ oxidoreductase activity|3-methylbutyraldehyde reductase (NADP) activity|3-methylbutanal reductase (NADP) activity|isoamyl alcohol oxidase (NADP) activity				KEGG_REACTION:R05686|RHEA:18525			ai	2011-04-12T11:19:27Z					molecular_function											owl:Class	
GO:0097164	biolink:NamedThing	ammonium ion metabolic process	The chemical reactions and pathways involving the ammonium ion.	tmpzr1t_l9r_go_relaxed.owl	ammonium metabolic process|ammonium ion metabolism							pr	2011-09-28T04:21:30Z					biological_process											owl:Class	
GO:0008396	biolink:NamedThing	oxysterol 7-alpha-hydroxylase activity	Catalysis of the reaction: an oxysterol + NADPH + O2 = 7-alpha-hydroxylated oxysterol + NADP+ + H2O.	tmpzr1t_l9r_go_relaxed.owl	cytochrome P450 CYP7B1				Reactome:R-HSA-5602885|Reactome:R-HSA-192178|Reactome:R-HSA-191972|Reactome:R-HSA-192065									molecular_function											owl:Class	
GO:0001860	biolink:NamedThing	complement component C3d receptor activity	Combining with the C3d product of the complement cascade and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0048847	biolink:NamedThing	adenohypophysis formation	The process that gives rise to adenohypophysis. This process pertains to the initial formation of a structure from unspecified parts. The adenohypophysis is the anterior part of the pituitary. It secretes a variety of hormones and its function is regulated by the hypothalamus.	tmpzr1t_l9r_go_relaxed.owl	anterior pituitary gland biosynthesis|anterior pituitary biosynthesis|adenophysis biosynthesis|adenophysis formation|anterior pituitary gland formation|anterior pituitary formation													biological_process											owl:Class	
GO:0050208	biolink:NamedThing	polysialic-acid O-acetyltransferase activity	Catalysis of the reaction: acetyl-CoA + an alpha-2,8-linked polymer of sialic acid = CoA + polysialic acid acetylated at O-7 or O-9.	tmpzr1t_l9r_go_relaxed.owl	acetyl-CoA:polysialic-acid O-acetyltransferase activity				MetaCyc:POLYSIALIC-ACID-O-ACETYLTRANSFERASE-RXN|RHEA:11604|EC:2.3.1.136									molecular_function											owl:Class	
GO:2000518	biolink:NamedThing	negative regulation of T-helper 1 cell activation	Any process that stops, prevents or reduces the frequency, rate or extent of T-helper 1 cell activation.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of Th1 cell activation							ebc	2011-03-22T10:40:26Z					biological_process											owl:Class	
GO:0016546	biolink:NamedThing	male courtship behavior, proboscis-mediated licking	The process during courtship where the male fly licks the genitalia of a stationary female fly with his proboscis. An example of this is found in Drosophila melanogaster.	tmpzr1t_l9r_go_relaxed.owl	male courtship behaviour, proboscis-mediated licking|male courtship behavior, licking|male courtship behaviour, licking													biological_process											owl:Class	
GO:0050042	biolink:NamedThing	lactate-malate transhydrogenase activity	Catalysis of the reaction: (S)-lactate + oxaloacetate = malate + pyruvate.	tmpzr1t_l9r_go_relaxed.owl	malate-lactate transhydrogenase activity|(S)-lactate:oxaloacetate oxidoreductase activity				EC:1.1.99.7|RHEA:10984|KEGG_REACTION:R01447|MetaCyc:LACTATE-MALATE-TRANSHYDROGENASE-RXN									molecular_function											owl:Class	
GO:0004610	biolink:NamedThing	phosphoacetylglucosamine mutase activity	Catalysis of the reaction: N-acetyl-alpha-D-glucosamine 1-phosphate = N-acetyl-D-glucosamine 6-phosphate.	tmpzr1t_l9r_go_relaxed.owl	N-acetyl-alpha-D-glucosamine 1,6-phosphomutase activity|N-acetylglucosamine-phosphate mutase activity|N-acetyl-D-glucosamine 1,6-phosphomutase activity|acetylaminodeoxyglucose phosphomutase activity|acetylglucosamine phosphomutase activity|phospho-N-acetylglucosamine mutase activity				Reactome:R-HSA-446185|RHEA:23804|EC:5.4.2.3|KEGG_REACTION:R08193|MetaCyc:PHOSACETYLGLUCOSAMINEMUT-RXN									molecular_function											owl:Class	
GO:0031567	biolink:NamedThing	mitotic cell size control checkpoint signaling	A signal transduction process that contributes to a cell size control checkpoint during mitosis.	tmpzr1t_l9r_go_relaxed.owl	mitotic cell cycle cell size control checkpoint|signal transduction involved in cell size control checkpoint|mitotic cell size control checkpoint											GO:0072471		biological_process											owl:Class	
GO:0098899	biolink:NamedThing	spine apparatus lumen	The volume enclosed by the spine apparatus membrane.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0042242	biolink:NamedThing	cobyrinic acid a,c-diamide synthase activity	Catalysis of the conversion of cobyrinic acid to cobyrinic acid a,c-diamide via the intermediate formation of cobyrinic acid c-monoamide.	tmpzr1t_l9r_go_relaxed.owl	cobyrinate a,c-diamide synthase activity|cobyrinate a,c diamide synthase activity|cobyrinate a c diamide synthase activity|CobB|cobyrinate a c-diamide synthase activity				EC:6.3.5.11|RHEA:26289							GO:0043775		molecular_function											owl:Class	
GO:0090323	biolink:NamedThing	prostaglandin secretion involved in immune response	The regulated release of a prostaglandin that contributes to the immune response. Prostaglandins are a group of biologically active metabolites which contain a cyclopentane ring.	tmpzr1t_l9r_go_relaxed.owl						Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.		tb	2010-05-12T10:41:04Z					biological_process											owl:Class	
GO:0019768	biolink:NamedThing	high-affinity IgE receptor activity	Combining with high affinity with an immunoglobulin of the IgE isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	high affinity IgE receptor activity|high affinity Fc receptor activity													molecular_function											owl:Class	
GO:0050171	biolink:NamedThing	phenol beta-glucosyltransferase activity	Catalysis of the reaction: UDP-glucose + a phenol = UDP + an aryl beta-D-glucoside.	tmpzr1t_l9r_go_relaxed.owl	uridine diphosphoglucosyltransferase activity|phenol-beta-D-glucosyltransferase activity|UDP-glucose glucosyltransferase activity|UDP-glucose:phenol beta-D-glucosyltransferase activity|UDPglucose:phenol beta-D-glucosyltransferase activity|UDPglucosyltransferase activity|phenol b-glucosyltransferase activity|UDP glucosyltransferase activity				MetaCyc:PHENOL-BETA-GLUCOSYLTRANSFERASE-RXN|EC:2.4.1.35									molecular_function											owl:Class	
GO:0047925	biolink:NamedThing	geranoyl-CoA carboxylase activity	Catalysis of the reaction: ATP + bicarbonate + geranoyl-CoA = 3-(4-methylpent-3-en-1-yl)pent-2-enedioyl-CoA + ADP + 2 H(+) + phosphate.	tmpzr1t_l9r_go_relaxed.owl	geranyl-CoA carboxylase activity|geranoyl coenzyme A carboxylase activity|geranoyl-CoA:carbon-dioxide ligase (ADP-forming)				MetaCyc:GERANOYL-COA-CARBOXYLASE-RXN|UM-BBD_reactionID:r1166|EC:6.4.1.5|KEGG_REACTION:R03494|RHEA:17701									molecular_function											owl:Class	
GO:0071159	biolink:NamedThing	NF-kappaB complex	A protein complex that consists of a homo- or heterodimer of members of a family of structurally related proteins that contain a conserved N-terminal region called the Rel homology domain (RHD). In the nucleus, NF-kappaB complexes act as transcription factors. In unstimulated cells, NF-kappaB dimers are sequestered in the cytoplasm by IkappaB monomers; signals that induce NF-kappaB activity cause degradation of IkappaB, allowing NF-kappaB dimers to translocate to the nucleus and induce gene expression.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-11-17T02:03:34Z					cellular_component											owl:Class	
GO:0001671	biolink:NamedThing	ATPase activator activity	Binds to and increases the activity of an ATP hydrolysis activity.	tmpzr1t_l9r_go_relaxed.owl	ATPase stimulator activity	https://github.com/geneontology/go-ontology/issues/20955			Reactome:R-HSA-5251955|Reactome:R-HSA-5251959									molecular_function											owl:Class	
GO:0002389	biolink:NamedThing	tolerance induction in Peyer's patch	Tolerance induction taking place in the Peyer's patches.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0044488	biolink:NamedThing	modulation of voltage-gated sodium channel activity in other organism	Any process in which an organism effects a change in the frequency, rate or extent of the activity of a voltage-gated sodium channel in another organism.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-02-01T11:48:25Z					biological_process											owl:Class	
GO:1905431	biolink:NamedThing	microcystin transport	The directed movement of a microcystin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl								cvs	2016-09-13T23:15:51Z					biological_process											owl:Class	
GO:0120058	biolink:NamedThing	positive regulation of small intestinal transit	Any process that increases the frequency, rate or extent of any small intestinal transit process, the migration of ingested material along the length of the small intestine.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of small intestine transit|positive regulation of small bowel transit							krc	2017-06-13T20:58:23Z					biological_process											owl:Class	
GO:0034195	biolink:NamedThing	L-galactonate catabolic process	The chemical reactions and pathways resulting in the breakdown of L-galactonate, the anion of L-galactonic acid.	tmpzr1t_l9r_go_relaxed.owl	L-galactonate degradation|L-galactonate breakdown|L-galactonate catabolism				MetaCyc:GALACTCAT-PWY									biological_process											owl:Class	
GO:0019886	biolink:NamedThing	antigen processing and presentation of exogenous peptide antigen via MHC class II	The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class II protein complex. The peptide antigen is typically, but not always, processed from a whole protein.	tmpzr1t_l9r_go_relaxed.owl	antigen presentation, exogenous antigen via MHC class II|antigen processing, exogenous antigen via major histocompatibility complex class II|antigen presentation, exogenous peptide antigen|exogenous peptide antigen processing and presentation via MHC class II											GO:0048005|GO:0042591		biological_process											owl:Class	
GO:0004754	biolink:NamedThing	saccharopine dehydrogenase (NAD+, L-lysine-forming) activity	Catalysis of the reaction: L-saccharopine + H(2)O + NAD(+) = 2-oxoglutarate + L-lysine + H(+) + NADH.	tmpzr1t_l9r_go_relaxed.owl	N6-(glutar-2-yl)-L-lysine:NAD oxidoreductase (L-lysine-forming)|N6-(L-1,3-dicarboxypropyl)-L-lysine:NAD+ oxidoreductase (L-lysine-forming)|6-N-(L-1,3-dicarboxypropyl)-L-lysine:NAD+ oxidoreductase (L-lysine-forming)|dehydrogenase, saccharopine (nicotinamide adenine dinucleotide, lysine forming)|epsilon-N-(L-glutaryl-2)-L-lysine:NAD oxidoreductase (L-lysine forming)				EC:1.5.1.7|MetaCyc:1.5.1.7-RXN|KEGG_REACTION:R00715|RHEA:12440									molecular_function											owl:Class	
GO:1903428	biolink:NamedThing	positive regulation of reactive oxygen species biosynthetic process	Any process that activates or increases the frequency, rate or extent of reactive oxygen species biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of reactive oxygen species generation|upregulation of reactive oxygen species biosynthetic process|up regulation of reactive oxygen species synthesis|upregulation of ROS generation|activation of reactive oxygen species synthesis|up-regulation of reactive oxygen species formation|upregulation of reactive oxygen species synthesis|activation of reactive oxygen species biosynthetic process|up-regulation of reactive oxygen species biosynthesis|up-regulation of ROS generation|upregulation of reactive oxygen species formation|positive regulation of reactive oxygen species biosynthesis|upregulation of reactive oxygen species anabolism|activation of reactive oxygen species anabolism|positive regulation of reactive oxygen species anabolism|up regulation of ROS formation|up regulation of reactive oxygen species biosynthesis|up regulation of reactive oxygen species formation|activation of ROS formation|up-regulation of reactive oxygen species anabolism|activation of reactive oxygen species generation|upregulation of ROS formation|up-regulation of reactive oxygen species generation|upregulation of reactive oxygen species biosynthesis|activation of ROS generation|positive regulation of reactive oxygen species synthesis|upregulation of reactive oxygen species generation|positive regulation of ROS formation|up regulation of reactive oxygen species generation|up regulation of ROS generation|up-regulation of reactive oxygen species synthesis|up-regulation of reactive oxygen species biosynthetic process|up-regulation of ROS formation|up regulation of reactive oxygen species biosynthetic process|positive regulation of ROS generation|positive regulation of reactive oxygen species formation|up regulation of reactive oxygen species anabolism|activation of reactive oxygen species formation|activation of reactive oxygen species biosynthesis							bf	2014-09-11T10:02:05Z					biological_process											owl:Class	
GO:0071690	biolink:NamedThing	cardiac muscle myosin thick filament assembly	The aggregation, arrangement and bonding together of proteins to form the myosin-based thick filaments of myofibrils in cardiac muscle.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-02-25T03:55:44Z					biological_process											owl:Class	
GO:0032611	biolink:NamedThing	interleukin-1 beta production	The appearance of interleukin-1 beta due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	tmpzr1t_l9r_go_relaxed.owl	interleukin-1 beta secretion|interleukin-1 beta biosynthetic process|IL-1 beta production											GO:0050720|GO:0050702		biological_process											owl:Class	
GO:0034028	biolink:NamedThing	5-(carboxyamino)imidazole ribonucleotide synthase activity	Catalysis of the reaction: 5-amino-1-(5-phospho-D-ribosyl)imidazole + ATP + bicarbonate = 5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole + ADP + 3 H(+) + phosphate.	tmpzr1t_l9r_go_relaxed.owl	5-amino-1-(5-phospho-D-ribosyl)imidazole:carbon-dioxide ligase (ADP-forming) activity|N5-carboxyaminoimidazole ribonucleotide synthetase activity|PurK|N5-CAIR synthetase activity				EC:6.3.4.18|RHEA:19317|MetaCyc:RXN0-742|KEGG_REACTION:R07404									molecular_function											owl:Class	
GO:0090587	biolink:NamedThing	protein-phosphocysteine-glucosamine phosphotransferase system transporter activity	Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein S-phosphocysteine + glucosamine (out) = protein cysteine + glucosamine-6-phosphate (in).	tmpzr1t_l9r_go_relaxed.owl								tb	2014-06-04T16:22:31Z					molecular_function											owl:Class	
GO:0047698	biolink:NamedThing	beta-alanyl-CoA ammonia-lyase activity	Catalysis of the reaction: beta-alanyl-CoA = acryloyl-CoA + NH3.	tmpzr1t_l9r_go_relaxed.owl	beta-alanyl coenzyme A ammonia-lyase activity|b-alanyl-CoA ammonia-lyase activity|beta-alanyl-CoA ammonia-lyase (acryloyl-CoA-forming)				EC:4.3.1.6|RHEA:12416|MetaCyc:BETA-ALANYL-COA-AMMONIA-LYASE-RXN									molecular_function											owl:Class	
GO:0044296	biolink:NamedThing	dendritic tuft	The terminal specialization found in some types of dendrites which consists of numerous small terminal branches, giving the dendrite a tufted appearance.	tmpzr1t_l9r_go_relaxed.owl	dendrite tuft				NIF_Subcellular:sao1340260079			jl	2010-02-04T04:03:29Z					cellular_component											owl:Class	
GO:0033509	biolink:NamedThing	glutamate catabolic process to propionate	The chemical reactions and pathways resulting in the breakdown of glutamate into other compounds, including propionate.	tmpzr1t_l9r_go_relaxed.owl	glutamate breakdown to propionate|glutamate degradation to propionate				MetaCyc:PWY-5088									biological_process											owl:Class	
GO:0031367	biolink:NamedThing	N-terminal peptidyl-glutamine deamination	The removal of an amino group from the side chain of an N-terminal glutamine residue of a protein.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0008872	biolink:NamedThing	glucarate dehydratase activity	Catalysis of the reaction: D-glucarate = 5-dehydro-4-deoxy-D-glucarate + H2O.	tmpzr1t_l9r_go_relaxed.owl	D-glucarate dehydratase activity|D-glucarate hydro-lyase (5-dehydro-4-deoxy-D-glucarate-forming)|D-glucarate hydro-lyase activity				RHEA:14573|EC:4.2.1.40|MetaCyc:GLUCARDEHYDRA-RXN									molecular_function											owl:Class	
GO:0102390	biolink:NamedThing	mycophenolic acid acyl-glucuronide esterase activity	Catalysis of the reaction: mycophenolic acid O-acyl-glucuronide(1-) + H2O <=> mycophenolate + H+ + D-glucopyranuronate.	tmpzr1t_l9r_go_relaxed.owl					RHEA:34179|MetaCyc:RXN-13605|EC:3.1.1.93									molecular_function											owl:Class	
GO:0031955	biolink:NamedThing	short-chain fatty acid-CoA ligase activity	Catalysis of the reaction: ATP + a short-chain fatty acid + CoA = AMP + diphosphate + an acyl-CoA; short-chain fatty acids are fatty acids with a chain length of less than C6.	tmpzr1t_l9r_go_relaxed.owl	short-chain fatty acid activation|short-chain-fatty-acid-CoA ligase activity|short-chain fatty-acid-CoA ligase activity													molecular_function											owl:Class	
GO:0070325	biolink:NamedThing	lipoprotein particle receptor binding	Binding to a lipoprotein particle receptor.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0001093	biolink:NamedThing	TFIIB-class transcription factor binding	Binding to a general RNA polymerase II transcription factor of the TFIIB class, one of the factors involved in formation of the preinitiation complex (PIC) by RNA polymerase II.	tmpzr1t_l9r_go_relaxed.owl								krc	2010-10-28T02:46:15Z					molecular_function											owl:Class	
GO:0018039	biolink:NamedThing	C-terminal peptidyl-glutamine amidation	The formation of a C-terminal peptidyl-glutamine amide by hydrolysis and oxidation of an interior Gln-Gly peptide in a secreted protein.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0086									biological_process											owl:Class	
GO:0032082	biolink:NamedThing	negative regulation of type III site-specific deoxyribonuclease activity	Any process that stops or reduces the rate of type III restriction endodeoxyribonuclease activity.	tmpzr1t_l9r_go_relaxed.owl	inhibition of type III restriction endodeoxyribonuclease activity|downregulation of type III restriction endodeoxyribonuclease activity|type III restriction enzyme inhibitor|type III restriction endodeoxyribonuclease inhibitor|negative regulation of type III restriction endodeoxyribonuclease activity|down-regulation of type III restriction endodeoxyribonuclease activity|down regulation of type III restriction endodeoxyribonuclease activity													biological_process											owl:Class	
GO:0032073	biolink:NamedThing	negative regulation of restriction endodeoxyribonuclease activity	Any process that stops or reduces the rate of a restriction endodeoxyribonuclease activity, the catalysis of endonucleolytic cleavage of DNA in a site-specific manner, resulting in double-strand breaks.	tmpzr1t_l9r_go_relaxed.owl	restriction alleviation|restriction endodeoxyribonuclease inhibitor|restriction enzyme inhibitor|down regulation of restriction endodeoxyribonuclease activity|downregulation of restriction endodeoxyribonuclease activity|inhibition of restriction endodeoxyribonuclease activity|down-regulation of restriction endodeoxyribonuclease activity													biological_process											owl:Class	
GO:2000444	biolink:NamedThing	negative regulation of toll-like receptor 21 signaling pathway	Any process that stops, prevents or reduces the frequency, rate or extent of toll-like receptor 21 signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of toll-like receptor 21 signalling pathway|negative regulation of TLR21 signaling pathway							bf	2011-03-04T10:32:29Z					biological_process											owl:Class	
GO:0018444	biolink:NamedThing	translation release factor complex	A heterodimeric complex involved in the release of a nascent polypeptide chain from a ribosome.	tmpzr1t_l9r_go_relaxed.owl	eukaryotic peptide chain release factor|peptide chain release factor													cellular_component											owl:Class	
GO:0005922	biolink:NamedThing	connexin complex	An assembly of six molecules of connexin, made in the Golgi apparatus and subsequently transported to the plasma membrane, where docking of two connexons on apposed plasma membranes across the extracellular space forms a gap junction.	tmpzr1t_l9r_go_relaxed.owl	connexon|connexon complex				NIF_Subcellular:sao445019788									cellular_component											owl:Class	
GO:0102511	biolink:NamedThing	pelargonidin 3-O-glucoside 7-O-glucosyltransferase (acyl-glucose dependent) activity	Catalysis of the reaction: pelargonidin 3-O-beta-D-glucoside + 1-O-vanilloyl-beta-D-glucose <=> pelargonidin 3,7-di-O-beta-D-glucoside + vanillate + H+.	tmpzr1t_l9r_go_relaxed.owl					EC:2.4.1.300|MetaCyc:RXN-14440									molecular_function											owl:Class	
GO:0072706	biolink:NamedThing	response to sodium dodecyl sulfate	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sodium dodecyl sulfate (SDS) stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to SDS							mah	2012-04-11T03:35:07Z					biological_process											owl:Class	
GO:1905846	biolink:NamedThing	regulation of cellular response to oxidopamine	Any process that modulates the frequency, rate or extent of cellular response to oxidopamine.	tmpzr1t_l9r_go_relaxed.owl								rz	2017-01-19T10:46:46Z					biological_process											owl:Class	
GO:0008772	biolink:NamedThing	[isocitrate dehydrogenase (NADP+)] kinase activity	Catalysis of the reaction: ATP + (isocitrate dehydrogenase (NADP)) = ADP + (isocitrate dehydrogenase (NADP)) phosphate.	tmpzr1t_l9r_go_relaxed.owl	isocitrate dehydrogenase kinase/phosphatase activity|IDH kinase/phosphatase activity|isocitrate dehydrogenase (NADP+) kinase activity|IDHK/P|isocitrate dehydrogenase kinase activity|ICDH kinase/phosphatase activity|ATP:isocitrate dehydrogenase (NADP+) phosphotransferase activity|isocitrate dehydrogenase kinase (phosphorylating) activity|isocitrate dehydrogenase (NADP) kinase activity|IDH kinase activity|IDH-K/P				RHEA:43540|EC:2.7.11.5|MetaCyc:PHOSICITDEHASE-RXN									molecular_function											owl:Class	
GO:0042106	biolink:NamedThing	gamma-delta T cell receptor complex	A T cell receptor complex in which the TCR heterodimer comprises gamma and delta chains, associated with the CD3 complex; recognizes antigen directly, without a requirement for processing and presentation by an MHC protein.	tmpzr1t_l9r_go_relaxed.owl	gamma-delta T-lymphocyte receptor complex|gamma-delta T-cell receptor complex|gamma-delta T lymphocyte receptor complex|gamma-delta TCR complex													cellular_component											owl:Class	
GO:0018752	biolink:NamedThing	epsilon-caprolactam lactamase activity	Catalysis of the reaction: epsilon-caprolactam + H2O = H+ + 6-aminohexanoate.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0448|MetaCyc:R561-RXN									molecular_function											owl:Class	
GO:0061819	biolink:NamedThing	telomeric DNA-containing double minutes formation	A telomere maintenance process that results in the formation of small fragments of circular extrachromosomal DNA elements which contain telomeric DNA. It is speculated that telomeric DNA-containing double minutes are formed through a recombination event between the telomere and chromosome-internal TTAGGG-like sequences. Telomeric DNA-containing double minutes appear as two closely positioned dots in metaphase.	tmpzr1t_l9r_go_relaxed.owl	TDMs formation							dph	2016-12-20T09:49:03Z					biological_process											owl:Class	
GO:0032478	biolink:NamedThing	heterotetrameric decaprenyl diphosphate synthase complex	A heterotetrameric complex located in the mitochondrial inner membrane that possesses di-trans,poly-cis-decaprenylcistransferase activity; involved in ubiquinone biosynthesis. In S. pombe it is a heterotetramer of Dlp1 and Dps1.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0046101	biolink:NamedThing	hypoxanthine biosynthetic process	The chemical reactions and pathways resulting in the formation of hypoxanthine, 6-hydroxy purine, an intermediate in the degradation of adenylate. Its ribonucleoside is known as inosine and its ribonucleotide as inosinate.	tmpzr1t_l9r_go_relaxed.owl	hypoxanthine synthesis|hypoxanthine biosynthesis|hypoxanthine formation|hypoxanthine anabolism													biological_process											owl:Class	
GO:0106245	biolink:NamedThing	L-serine-phosphatidylethanolamine phosphatidyltransferase activity	Catalysis of the reaction: L-1-phosphatidylethanolamine + L-serine <=> L-1-phosphatidylserine + ethanolamine.	tmpzr1t_l9r_go_relaxed.owl					RHEA:27606|EC:2.7.8.29			hjd	2020-01-22T15:27:57Z					molecular_function											owl:Class	
GO:0071304	biolink:NamedThing	cellular response to vitamin B6	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin B6 stimulus. Vitamin B6 encompasses pyridoxal, pyridoxamine and pyridoxine and the active form, pyridoxal phosphate.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-12-10T04:35:23Z					biological_process											owl:Class	
GO:0050508	biolink:NamedThing	glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity	Catalysis of the reaction: beta-D-glucuronosyl-(1,4)-N-acetyl-alpha-D-glucosaminyl-proteoglycan + UDP-N-acetyl-D-glucosamine = N-acetyl-alpha-D-glucosaminyl-(1,4)-beta-D-glucuronosyl-(1,4)-N-acetyl-alpha-D-glucosaminyl-proteoglycan + UDP.	tmpzr1t_l9r_go_relaxed.owl	glucuronyl-N-acetylglucosaminylproteoglycan alpha-1,4-N-acetylglucosaminyltransferase activity|UDP-N-acetyl-D-glucosamine:beta-D-glucuronosyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity|alpha-N-acetylglucosaminyltransferase II activity|glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-a-N-acetylglucosaminyltransferase activity				Reactome:R-HSA-2022851|RHEA:16213|Reactome:R-HSA-3656254|MetaCyc:2.4.1.224-RXN|Reactome:R-HSA-2022919|Reactome:R-HSA-9036283|Reactome:R-HSA-9036290|Reactome:R-HSA-3656261|EC:2.4.1.224									molecular_function											owl:Class	
GO:0018846	biolink:NamedThing	styrene-oxide isomerase activity	Catalysis of the reaction: styrene oxide = phenylacetaldehyde.	tmpzr1t_l9r_go_relaxed.owl	styrene-oxide isomerase (epoxide-cleaving)|styrene oxide isomerase activity|SOI activity				KEGG_REACTION:R02615|UM-BBD_reactionID:r0034|EC:5.3.99.7|RHEA:21604|MetaCyc:STYRENE-OXIDE-ISOMERASE-RXN									molecular_function											owl:Class	
GO:0102564	biolink:NamedThing	aurachin C epoxide hydrolase/isomerase activity	Catalysis of the reaction: aurachin C epoxide + H+ + NAD(P)H <=> aurachin B + H2O + NAD(P).	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-15030|RHEA:48728									molecular_function											owl:Class	
GO:0048473	biolink:NamedThing	D-methionine transport	The directed movement of D-methionine into, out of, within, or between cells.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0021672	biolink:NamedThing	rhombomere 7 structural organization	The process that contributes to creating the structural organization of rhombomere 7. This process pertains to the physical shaping of a rudimentary structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.	tmpzr1t_l9r_go_relaxed.owl	rhombomere 7 structural organisation													biological_process											owl:Class	
GO:0031289	biolink:NamedThing	actin phosphorylation	The transfer of one or more phosphate groups to an actin molecule.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0042135	biolink:NamedThing	neurotransmitter catabolic process	The chemical reactions and pathways resulting in the breakdown of any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell.	tmpzr1t_l9r_go_relaxed.owl	neurotransmitter catabolism|neurotransmitter breakdown|neurotransmitter degradation													biological_process											owl:Class	
GO:0018254	biolink:NamedThing	peptidyl-tyrosine adenylylation	The adenylylation of peptidyl-tyrosine to form peptidyl-O4'-(phospho-5'-adenosine)-L-tyrosine.	tmpzr1t_l9r_go_relaxed.owl	peptidyl-tyrosine adenylation				RESID:AA0203									biological_process											owl:Class	
GO:0051434	biolink:NamedThing	BH3 domain binding	Binding to a BH3 protein domain, present in Bcl-2 family members. The BH3 domain is a potent death domain and has an important role in protein-protein interactions and in cell death.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1902809	biolink:NamedThing	regulation of skeletal muscle fiber differentiation	Any process that modulates the frequency, rate or extent of skeletal muscle fiber differentiation.	tmpzr1t_l9r_go_relaxed.owl								mr	2014-03-26T21:18:26Z					biological_process											owl:Class	
GO:0060013	biolink:NamedThing	righting reflex	A reflex process in which an animal immediately tries to turn over after being placed in a supine position.	tmpzr1t_l9r_go_relaxed.owl	righting response													biological_process											owl:Class	
GO:0023003	biolink:NamedThing	nuclear migration to the embryo sac center	Migration of one of the four nuclei at each pole of the eight-nucleate embryo sac, to the center of the cell.	tmpzr1t_l9r_go_relaxed.owl	nuclear migration to the embryo sac centre|nucleus migration to the female gametophyte center|nucleus migration to the female gametophyte centre|nuclear migration to the megagametophyte center|nuclear migration to the female gametophyte center|nuclear migration to the female gametophyte centre|nuclear migration to the megagametophyte centre													biological_process											owl:Class	
GO:0060870	biolink:NamedThing	cell wall disassembly involved in floral organ abscission	A cellular process that results in the breakdown of the cell wall that contributes to the process of floral organ abscission.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-08-12T07:15:36Z					biological_process											owl:Class	
GO:0047282	biolink:NamedThing	dTDP-dihydrostreptose-streptidine-6-phosphate dihydrostreptosyltransferase activity	Catalysis of the reaction: dTDP-L-dihydrostreptose + streptidine 6-phosphate = O-(1->4)-alpha-L-dihydrostreptosyl-streptidine 6-phosphate + dTDP + H(+).	tmpzr1t_l9r_go_relaxed.owl	dTDPdihydrostreptose-streptidine-6-phosphate dihydrostreptosyltransferase activity|dTDP-L-dihydrostreptose:streptidine-6-phosphate dihydrostreptosyltransferase activity|thymidine diphosphodihydrostreptose-streptidine 6-phosphate dihydrostreptosyltransferase activity				EC:2.4.2.27|KEGG_REACTION:R04222|RHEA:24392|MetaCyc:2.4.2.27-RXN									molecular_function											owl:Class	
GO:0071381	biolink:NamedThing	cellular response to prostaglandin F stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin F stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-12-11T03:34:57Z					biological_process											owl:Class	
GO:0034652	biolink:NamedThing	extrachromosomal circular DNA localization involved in cell aging	A process in which extrachromosomal circular DNA molecules are transported to, or maintained in, a specific location in cells contributing to their aging.	tmpzr1t_l9r_go_relaxed.owl	extrachromosomal circular DNA localisation involved in cell aging|extrachromosomal circular DNA localization during cell ageing|extrachromosomal circular DNA localization during cell aging					Note that the term string was changed to be consistent with placement of this term in cell aging hierarchy.								biological_process											owl:Class	
GO:0097295	biolink:NamedThing	morphine biosynthetic process	The chemical reactions and pathways resulting in the formation of morphine, 17-methyl-7,8-didehydro-4,5alpha-epoxymorphinan-3,6alpha-diol. Morphine is a highly potent opiate analgesic psychoactive drug obtained form the opium poppy, Papaver somniferum.	tmpzr1t_l9r_go_relaxed.owl	morphine biosynthesis|morphine anabolism|morphine synthesis|morphine formation							pr	2012-05-02T09:51:19Z					biological_process											owl:Class	
GO:1900942	biolink:NamedThing	negative regulation of (Z)-nonadeca-1,14-diene biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of (Z)-nonadeca-1,14-diene biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	down regulation of (Z)-nonadeca-1,14-diene synthesis|negative regulation of (Z)-nonadeca-1,14-diene anabolism|inhibition of (Z)-nonadeca-1,14-diene anabolism|downregulation of (Z)-nonadeca-1,14-diene formation|negative regulation of (Z)-nonadeca-1,14-diene synthesis|inhibition of (Z)-nonadeca-1,14-diene biosynthesis|downregulation of (Z)-nonadeca-1,14-diene biosynthetic process|down regulation of (Z)-nonadeca-1,14-diene anabolism|down regulation of (Z)-nonadeca-1,14-diene biosynthetic process|down-regulation of (Z)-nonadeca-1,14-diene biosynthesis|down-regulation of (Z)-nonadeca-1,14-diene anabolism|down-regulation of (Z)-nonadeca-1,14-diene synthesis|inhibition of (Z)-nonadeca-1,14-diene synthesis|inhibition of (Z)-nonadeca-1,14-diene formation|negative regulation of (Z)-nonadeca-1,14-diene biosynthesis|down-regulation of (Z)-nonadeca-1,14-diene biosynthetic process|negative regulation of (Z)-nonadeca-1,14-diene formation|down-regulation of (Z)-nonadeca-1,14-diene formation|inhibition of (Z)-nonadeca-1,14-diene biosynthetic process|downregulation of (Z)-nonadeca-1,14-diene biosynthesis|down regulation of (Z)-nonadeca-1,14-diene formation|downregulation of (Z)-nonadeca-1,14-diene anabolism|downregulation of (Z)-nonadeca-1,14-diene synthesis|down regulation of (Z)-nonadeca-1,14-diene biosynthesis							tt	2012-06-14T03:17:54Z					biological_process											owl:Class	
GO:0016990	biolink:NamedThing	arginine deiminase activity	Catalysis of the reaction: L-arginine + H2O = L-citrulline + NH3.	tmpzr1t_l9r_go_relaxed.owl	L-arginine deiminase activity|citrulline iminase activity|L-arginine iminohydrolase activity|arginine dihydrolase activity				RHEA:19597|MetaCyc:ARGININE-DEIMINASE-RXN|EC:3.5.3.6									molecular_function											owl:Class	
GO:0034886	biolink:NamedThing	gamma-aminovinylacetate deaminase activity	Catalysis of the reaction: gamma-aminovinylacetate + H2O = succinic semialdehyde + NH3.	tmpzr1t_l9r_go_relaxed.owl					EC:3.5.99.-|UM-BBD_reactionID:r1351									molecular_function											owl:Class	
GO:0003112	biolink:NamedThing	positive regulation of heart rate by neuronal epinephrine	The process in which the secretion of epinephrine from nerve endings increases the rate of heart muscle contraction.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of heart rate by neuronal adrenaline													biological_process											owl:Class	
GO:0044816	biolink:NamedThing	Nsk1-Dlc1 complex	A dimer of Nsk1 (nucleolus spindle kinetochore 1) and the dynein light chain, Dlc1. The dimers form an oligomeric chain structure. Functions in the regulation of kinetochore-microtubule interactions and chromosome segregation.	tmpzr1t_l9r_go_relaxed.owl								jl	2013-10-21T14:38:16Z					cellular_component											owl:Class	
GO:0033221	biolink:NamedThing	ATPase-coupled urea transmembrane transporter activity	Catalysis of the reaction: ATP + H2O + urea(out) = ADP + phosphate + urea(in).	tmpzr1t_l9r_go_relaxed.owl	ATP-dependent urea transmembrane transporter activity|carbamide-transporting ATPase activity|urea-transporting ATPase activity				RHEA:32803									molecular_function											owl:Class	
GO:0047403	biolink:NamedThing	lacto-N-biosidase activity	Catalysis of the reaction: H2O + beta-D-Gal-(1,3)-beta-D-GlcNAc-(1,3)-beta-D-Gal-(1,4)-D-Glc = beta-D-Gal-(1,4)-D-Glc + beta-D-Gal-(1,3)-D-GlcNAc.	tmpzr1t_l9r_go_relaxed.owl	oligosaccharide lacto-N-biosylhydrolase activity				EC:3.2.1.140|RHEA:21568									molecular_function											owl:Class	
GO:0003712	biolink:NamedThing	transcription coregulator activity	A transcription regulator activity that modulates the transcription of specific gene sets via binding to a DNA-bound DNA-binding transcription factor, either on its own or as part of a complex. Coregulators often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second class remodels the conformation of chromatin in an ATP-dependent fashion. A third class modulates interactions of DNA-bound DNA-binding transcription factors with other transcription coregulators.	tmpzr1t_l9r_go_relaxed.owl	RNA polymerase II transcriptional cofactor activity|transcription cofactor activity|transcriptional co-regulator	https://github.com/geneontology/go-ontology/issues/20464|https://github.com/geneontology/go-ontology/issues/15998|https://github.com/geneontology/go-ontology/issues/15665|https://github.com/geneontology/go-ontology/issues/20962|https://github.com/geneontology/go-ontology/issues/20862|https://github.com/geneontology/go-ontology/issues/20253|https://github.com/geneontology/go-ontology/issues/15536				Usage guidance: Most transcription coregulators do not bind DNA. Those that do usually bind DNA either in a non-specific or non-direct manner. If a protein binds DNA specifically, consider annotating to GO:0003700 DNA binding transcription factor activity.		krc	2010-11-24T03:02:15Z			GO:0016455|GO:0001104		molecular_function											owl:Class	
GO:0047074	biolink:NamedThing	4-hydroxycatechol 1,2-dioxygenase activity	Catalysis of the reaction: O2 + benzene-1,2,4-triol = maleylacetate.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:R308-RXN|MetaCyc:RXN-10137|RHEA:35595|EC:1.13.11.37									molecular_function											owl:Class	
GO:0034189	biolink:NamedThing	very-low-density lipoprotein particle binding	Binding to a very-low-density lipoprotein particle, a triglyceride-rich lipoprotein particle that is typically composed of APOB100, APOE and APOCs and has a density of about 1.006 g/ml and a diameter of between 20-80 nm.	tmpzr1t_l9r_go_relaxed.owl	VLDL binding|very-low-density lipoprotein binding													molecular_function											owl:Class	
GO:0003941	biolink:NamedThing	L-serine ammonia-lyase activity	Catalysis of the reaction: L-serine = pyruvate + NH3.	tmpzr1t_l9r_go_relaxed.owl	L-hydroxyaminoacid dehydratase activity|L-serine deaminase activity|L-serine dehydratase activity|L-serine ammonia-lyase (pyruvate-forming) activity|L-serine hydro-lyase (deaminating) activity|L-serine dehydration activity|serine deaminase activity				MetaCyc:4.3.1.17-RXN|EC:4.3.1.17|RHEA:19169	Note that this function was formerly EC:4.3.1.13.								molecular_function											owl:Class	
GO:0080160	biolink:NamedThing	selenate transport	The directed movement of selenate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl								dhl	2010-09-01T04:17:38Z					biological_process											owl:Class	
GO:0097258	biolink:NamedThing	20-hydroxy-leukotriene B4 omega oxidase activity	Catalysis of the reaction:  20-hydroxy-leukotriene B4 + O2 + reduced [NADPH-hemoprotein reductase] = 20-oxo-leukotriene B4 + H+ + 2 H2O + oxidized [NADPH-hemoprotein reductase].	tmpzr1t_l9r_go_relaxed.owl	20-hydroxy-leukotriene B4 omega-oxidase activity|20-hydroxy-leukotriene B4 omega-oxidation				Reactome:R-HSA-2161745|RHEA:48668			pr	2012-03-07T03:37:53Z					molecular_function											owl:Class	
GO:0062041	biolink:NamedThing	positive regulation of meiotic sister chromatid arm separation	Any process that increases the rate or exent of meiotic sister chromatid arm separation, the cell cycle process in which sister chromatid arms are physically detached from each other during meiosis.	tmpzr1t_l9r_go_relaxed.owl								dph	2018-05-04T18:20:28Z					biological_process											owl:Class	
GO:0019623	biolink:NamedThing	atrazine catabolic process to urea	The chemical reactions and pathways resulting in the breakdown of atrazine, a triazine ring-containing herbicide, into urea.	tmpzr1t_l9r_go_relaxed.owl	atrazine breakdown to urea|atrazine degradation to urea													biological_process											owl:Class	
GO:0043821	biolink:NamedThing	propionyl-CoA:succinate CoA-transferase activity	Catalysis of the reaction: succinate + propionyl-CoA = succinyl-CoA + propionate.	tmpzr1t_l9r_go_relaxed.owl	propionyl-CoA:succinate CoA transferase activity|propionyl-CoA succinate CoA-transferase activity				RHEA:28010|MetaCyc:RXN0-268									molecular_function											owl:Class	
GO:1905636	biolink:NamedThing	positive regulation of RNA polymerase II regulatory region sequence-specific DNA binding	Any process that activates or increases the frequency, rate or extent of RNA polymerase II regulatory region sequence-specific DNA binding.	tmpzr1t_l9r_go_relaxed.owl	up regulation of RNA polymerase II regulatory region sequence-specific DNA binding|activation of RNA polymerase II regulatory region sequence-specific DNA binding|upregulation of RNA polymerase II regulatory region sequence-specific DNA binding|up-regulation of RNA polymerase II regulatory region sequence-specific DNA binding							bc	2016-11-03T12:03:07Z					biological_process											owl:Class	
GO:0099574	biolink:NamedThing	regulation of protein catabolic process at synapse, modulating synaptic transmission	Any process that modulates synaptic transmission by regulating protein degradation at the synapse.	tmpzr1t_l9r_go_relaxed.owl						Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.								biological_process											owl:Class	
GO:0098608	biolink:NamedThing	methylselenol demethylase activity	Catalysis of the reaction: methylselenol + H2O => H2Se + CH3OH.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-2408530			dos	2014-04-16T11:28:00Z					molecular_function											owl:Class	
GO:1901140	biolink:NamedThing	p-coumaryl alcohol transport	The directed movement of a p-coumaryl alcohol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	4-hydroxycinnamyl alcohol transport							tb	2012-07-12T09:46:16Z					biological_process											owl:Class	
GO:0034018	biolink:NamedThing	ascopyrone tautomerase activity	Catalysis of the reaction: 1,5-anhydro-4-deoxy-D-glycero-hex-3-en-2-ulose = 1,5-anhydro-4-deoxy-D-glycero-hex-1-en-3-ulose.	tmpzr1t_l9r_go_relaxed.owl	APTM|1,5-anhydro-D-glycero-hex-3-en-2-ulose delta3-delta1-isomerase activity|ascopyrone P tautomerase activity|1,5-anhydro-D-glycero-hex-3-en-2-ulose tautomerase activity|APM tautomerase activity|ascopyrone isomerase activity|ascopyrone intramolecular oxidoreductase activity				MetaCyc:5.3.3.15-RXN|RHEA:22568|EC:5.3.2.7									molecular_function											owl:Class	
GO:0031741	biolink:NamedThing	type B gastrin/cholecystokinin receptor binding	Binding to a type B gastrin/cholecystokinin receptor.	tmpzr1t_l9r_go_relaxed.owl	type B gastrin/cholecystokinin receptor ligand													molecular_function											owl:Class	
GO:0047002	biolink:NamedThing	L-arabinitol 2-dehydrogenase activity	Catalysis of the reaction: L-arabinitol + NAD(+) = L-ribulose + H(+) + NADH.	tmpzr1t_l9r_go_relaxed.owl	L-arabinitol 2-dehydrogenase (ribulose forming) activity				MetaCyc:1.1.1.13-RXN|EC:1.1.1.13|KEGG_REACTION:R02441|RHEA:21356									molecular_function											owl:Class	
GO:1900130	biolink:NamedThing	regulation of lipid binding	Any process that modulates the frequency, rate or extent of lipid binding.	tmpzr1t_l9r_go_relaxed.owl								pm	2012-02-23T04:05:03Z					biological_process											owl:Class	
GO:0004755	biolink:NamedThing	saccharopine dehydrogenase (NADP+, L-glutamate-forming) activity	Catalysis of the reaction: L-saccharopine + H(2)O + NADP(+) = L-allysine + L-glutamate + H(+) + NADPH.	tmpzr1t_l9r_go_relaxed.owl	aminoadipic semialdehyde-glutamate reductase activity|saccharopine reductase activity|aminoadipic semialdehyde-glutamic reductase activity|saccharopine (nicotinamide adenine dinucleotide phosphate, glutamate-forming) dehydrogenase activity|aminoadipate semialdehyde-glutamate reductase activity|epsilon-N-(L-glutaryl-2)-L-lysine:NAD+(P) oxidoreductase (L-2-aminoadipate-semialdehyde forming)|N6-(L-1,3-dicarboxypropyl)-L-lysine:NADP+ oxidoreductase (L-glutamate-forming)|6-N-(L-1,3-dicarboxypropyl)-L-lysine:NADP+ oxidoreductase (L-glutamate-forming)				MetaCyc:RXN3O-127|RHEA:10020|EC:1.5.1.10|KEGG_REACTION:R02315									molecular_function											owl:Class	
GO:0039661	biolink:NamedThing	host organelle outer membrane	The outer, i.e. cytoplasm-facing in a cellular organelle, lipid bilayer of an organelle envelope, occurring in a host cell.	tmpzr1t_l9r_go_relaxed.owl								bf	2013-08-25T10:44:43Z					cellular_component											owl:Class	
GO:0098841	biolink:NamedThing	protein localization to cell division site after cytokinesis	A cellular protein localization process in which a protein is transported to, or maintained at, the site of cell division following cytokinesis.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0042151	biolink:NamedThing	nematocyst	An organelle found in cnidoblast (nematoblast) cells. When matured, these stinging organelles store toxins and can deliver them when the cnidocil (a short extension of the cnidocyst) is stimulated by a prey or another stimulus.	tmpzr1t_l9r_go_relaxed.owl	cnidocyst				Wikipedia:Cnidocyte									cellular_component											owl:Class	
GO:0036485	biolink:NamedThing	dorsolateral trunk neural crest cell migration	The movement of trunk neural crest cells from the neural tube, travelling dorso-laterally into the ectoderm and continuing toward the ventral midline of the belly. These migrating trunk neural crest cells become melanocytes, the melanin-forming pigment cells.	tmpzr1t_l9r_go_relaxed.owl	dorsolateral trunk NCC migration							bf	2014-08-26T15:29:04Z					biological_process											owl:Class	
GO:0016608	biolink:NamedThing	growth hormone-releasing hormone activity	The action characteristic of growth hormone-releasing hormone, any of a family of peptide hormones that act on the anterior pituitary to stimulate the secretion of growth hormone and exert a trophic effect on the gland.	tmpzr1t_l9r_go_relaxed.owl	GHRH activity|GHRF activity													molecular_function											owl:Class	
GO:0019602	biolink:NamedThing	toluene oxidation via 3-hydroxytoluene	The degradation of toluene to form pyruvate and acetaldehyde; the first step in the pathway is the oxidation of toluene to form 3-hydroxytoluene (m-cresol).	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:TOLUENE-DEG-3-OH-PWY									biological_process											owl:Class	
GO:0071618	biolink:NamedThing	lysophosphatidylethanolamine acyltransferase activity	Catalysis of the transfer of acyl groups from an acyl-CoA to lysophosphatidylethanolamine.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-02-08T04:59:07Z					molecular_function											owl:Class	
GO:0042544	biolink:NamedThing	melibiose biosynthetic process	The chemical reactions and pathways resulting in the formation of melibiose, the disaccharide 6-O-alpha-D-galactopyranosyl-D-glucose.	tmpzr1t_l9r_go_relaxed.owl	melibiose formation|melibiose synthesis|melibiose biosynthesis|melibiose anabolism													biological_process											owl:Class	
GO:1901431	biolink:NamedThing	regulation of response to cycloalkane	Any process that modulates the frequency, rate or extent of response to cycloalkane.	tmpzr1t_l9r_go_relaxed.owl								tt	2012-10-01T21:01:58Z					biological_process											owl:Class	
GO:0044399	biolink:NamedThing	multi-species biofilm formation	A process in which planktonically growing microorganisms of different species grow at a liquid-air interface or on a solid substrate under the flow of a liquid and produce extracellular polymers that facilitate matrix formation, resulting in a change in the organisms' growth rate and gene transcription.	tmpzr1t_l9r_go_relaxed.owl	multi-species submerged biofilm formation|multi-species surface biofilm formation|multi-species biofilm formation in or on host organism|multi-species biofilm formation on inanimate substrate											GO:0090607|GO:0090608|GO:0044400|GO:0044401		biological_process											owl:Class	
GO:0047149	biolink:NamedThing	thetin-homocysteine S-methyltransferase activity	Catalysis of the reaction: L-homocysteine + dimethylsulfonioacetate = (methylthio)acetate + L-methionine + H(+).	tmpzr1t_l9r_go_relaxed.owl	dimethylsulfonioacetate:L-homocysteine S-methyltransferase activity|dimethylthetin-homocysteine methyltransferase activity|thetin-homocysteine methylpherase activity				RHEA:22788|EC:2.1.1.3|KEGG_REACTION:R04153|MetaCyc:2.1.1.3-RXN									molecular_function											owl:Class	
GO:0018803	biolink:NamedThing	4-(2-carboxyphenyl)-2-oxobut-3-enoate aldolase activity	Catalysis of the reaction: (3E)-4-(2-carboxyphenyl)-2-oxobut-3-enoate = 2-carboxybenzaldehyde + pyruvate.	tmpzr1t_l9r_go_relaxed.owl	trans-2'-carboxybenzalpyruvate hydratase-aldolase activity|(3Z)-4-(2-carboxyphenyl)-2-oxobut-3-enoate 2-carboxybenzaldehyde-lyase (pyruvate-forming)|2'-carboxybenzalpyruvate aldolase activity|(3Z)-4-(2-carboxyphenyl)-2-oxobut-3-enoate 2-carboxybenzaldehyde-lyase activity|(3E)-4-(2-carboxyphenyl)-2-oxobut-3-enoate 2-carboxybenzaldehyde-lyase activity				RHEA:16453|EC:4.1.2.34|UM-BBD_reactionID:r0487|MetaCyc:4.1.2.34-RXN									molecular_function											owl:Class	
GO:0021643	biolink:NamedThing	vagus nerve maturation	A developmental process, independent of morphogenetic (shape) change, that is required for the vagus nerve to attain its fully functional state. This nerve is primarily sensory but also has visceromotor components. It originates in the brain stem and controls many autonomic functions of the heart, lungs, stomach, pharynx, larynx, trachea, esophagus and other gastrointestinal tract components. It controls some motor functions such as speech. The sensory branches mediate sensation from the pharynx, larynx, thorax and abdomen; it also innervates taste buds in the epiglottis.	tmpzr1t_l9r_go_relaxed.owl	CN X maturation													biological_process											owl:Class	
GO:0007139	biolink:NamedThing	meiotic telophase II	The cell cycle phase which follows anaphase II of meiosis and during which the chromosomes arrive at the poles of the cell and the division of the cytoplasm starts.	tmpzr1t_l9r_go_relaxed.owl						Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).								biological_process											owl:Class	
GO:0014810	biolink:NamedThing	positive regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion	Any process that activates, maintains or increases the frequency, rate or extent of skeletal muscle contraction via the regulation of the release of sequestered calcium ion by sarcoplasmic reticulum into cytosol. The sarcoplasmic reticulum is the endoplasmic reticulum of striated muscle, specialised for the sequestration of calcium ions that are released upon receipt of a signal relayed by the T tubules from the neuromuscular junction.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1902629	biolink:NamedThing	regulation of mRNA stability involved in cellular response to UV	Any regulation of mRNA stability that is involved in cellular response to UV.	tmpzr1t_l9r_go_relaxed.owl	regulation of mRNA stability involved in cellular response to ultraviolet radiation stimulus|regulation of mRNA stability involved in cellular response to UV radiation stimulus|regulation of mRNA stability involved in cellular response to UV light stimulus|regulation of mRNA stability involved in cellular response to ultraviolet light stimulus							mah	2014-01-17T12:23:38Z					biological_process											owl:Class	
GO:0006583	biolink:NamedThing	melanin biosynthetic process from tyrosine	The chemical reactions and pathways resulting in the formation of melanin from other compounds, including tyrosine.	tmpzr1t_l9r_go_relaxed.owl	melanin synthesis from tyrosine|melanin formation from tyrosine|melanin anabolism from tyrosine													biological_process											owl:Class	
GO:0102074	biolink:NamedThing	OPC6-trans-2-enoyl-CoA hydratase activity	Catalysis of the reaction: OPC6-3-hydroxyacyl-CoA <=> OPC6-trans-2-enoyl-CoA + H2O.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-10704									molecular_function											owl:Class	
GO:0045243	biolink:NamedThing	cytosolic isocitrate dehydrogenase complex (NAD+)	Cytosolic complex that possesses isocitrate dehydrogenase (NAD+) activity.	tmpzr1t_l9r_go_relaxed.owl	isocitrate dehydrogenase complex (NAD+)													cellular_component											owl:Class	
GO:0045242	biolink:NamedThing	isocitrate dehydrogenase complex (NAD+)	Complex that possesses isocitrate dehydrogenase (NAD+) activity.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:1901182	biolink:NamedThing	regulation of camalexin biosynthetic process	Any process that modulates the frequency, rate or extent of camalexin biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of camalexin synthesis|regulation of camalexin biosynthesis|regulation of camalexin anabolism|regulation of camalexin formation							tb	2012-07-23T02:16:52Z					biological_process											owl:Class	
GO:0050365	biolink:NamedThing	tryptophanamidase activity	Catalysis of the reaction: L-tryptophanamide + H(2)O = L-tryptophan + NH(4)(+).	tmpzr1t_l9r_go_relaxed.owl	L-tryptophanamide amidohydrolase activity|L-tryptophan aminopeptidase|tryptophan aminopeptidase				KEGG_REACTION:R00682|MetaCyc:TRYPTOPHANAMIDASE-RXN|EC:3.5.1.57|RHEA:11012									molecular_function											owl:Class	
GO:0050342	biolink:NamedThing	tocopherol O-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + gamma-tocopherol = S-adenosyl-L-homocysteine + alpha-tocopherol.	tmpzr1t_l9r_go_relaxed.owl	S-adenosyl-L-methionine:gamma-tocopherol 5-O-methyltransferase activity|gamma-tocopherol methyltransferase activity				EC:2.1.1.95|MetaCyc:TOCOPHEROL-O-METHYLTRANSFERASE-RXN|RHEA:24012									molecular_function											owl:Class	
GO:0102085	biolink:NamedThing	N-(4-aminobenzoyl)-L-glutamate synthetase activity	Catalysis of the reaction: 4-aminobenzoate + L-glutamate + ATP <=> H+ + p-aminobenzoyl glutamate + AMP + diphosphoric acid.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-10884									molecular_function											owl:Class	
GO:0001096	biolink:NamedThing	TFIIF-class transcription factor complex binding	Binding to a general RNA polymerase II transcription factor belonging to the TFIIF complex, one of the factors involved in formation of the preinitiation complex (PIC) by RNA polymerase II.	tmpzr1t_l9r_go_relaxed.owl	TFIIF-class transcription factor binding							krc	2010-10-28T02:51:20Z					molecular_function											owl:Class	
GO:0070523	biolink:NamedThing	11-beta-hydroxysteroid dehydrogenase (NAD+) activity	Catalysis of the reaction: an 11-beta-hydroxysteroid + NAD+ = an 11-oxosteroid + NADH + H+.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/21915			Wikipedia:11beta-hydroxysteroid_dehydrogenase|RHEA:53116									molecular_function											owl:Class	
GO:0003845	biolink:NamedThing	11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity	Catalysis of the reaction: an 11-beta-hydroxysteroid + NAD(P)+ = an 11-oxosteroid + NAD(P)H + H(+).	tmpzr1t_l9r_go_relaxed.owl	11beta-hydroxysteroid dehydrogenase|11beta-hydroxy steroid dehydrogenase|corticosteroid 11-reductase|corticosteroid 11beta-dehydrogenase|beta-hydroxysteroid dehydrogenase	https://github.com/geneontology/go-ontology/issues/21915			Reactome:R-HSA-194023|MetaCyc:11-BETA-HYDROXYSTEROID-DEHYDROGENASE-RXN|Wikipedia:11beta-hydroxysteroid_dehydrogenase									molecular_function											owl:Class	
GO:0008615	biolink:NamedThing	pyridoxine biosynthetic process	The chemical reactions and pathways resulting in the formation of pyridoxine, 2-methyl-3-hydroxy-4,5-bis(hydroxymethyl)pyridine, one of the vitamin B6 compounds.	tmpzr1t_l9r_go_relaxed.owl	pyridoxine biosynthesis|pyridoxine synthesis|pyridoxine formation|pyridoxine anabolism													biological_process											owl:Class	
GO:0072647	biolink:NamedThing	interferon-epsilon production	The appearance of interferon-epsilon due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	tmpzr1t_l9r_go_relaxed.owl	IFN-epsilon production|interferon-epsilon secretion|IFNE production					Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.						GO:0072648		biological_process											owl:Class	
GO:0050049	biolink:NamedThing	leucine dehydrogenase activity	Catalysis of the reaction: L-leucine + H2O + NAD+ = 4-methyl-2-oxopentanoate + NH3 + NADH.	tmpzr1t_l9r_go_relaxed.owl	LeuDH activity|L-leucine:NAD+ oxidoreductase, deaminating|L-leucine:NAD+ oxidoreductase (deaminating)|L-leucine dehydrogenase activity				MetaCyc:LEUCINE-DEHYDROGENASE-RXN|EC:1.4.1.9|RHEA:12220									molecular_function											owl:Class	
GO:0050340	biolink:NamedThing	thymidylate 5'-phosphatase activity	Catalysis of the reaction: thymidylate + H2O = thymidine + phosphate.	tmpzr1t_l9r_go_relaxed.owl	deoxythymidylic 5'-nucleotidase activity|thymidylate 5'-phosphohydrolase activity|thymidylate 5' phosphatase activity|deoxythymidylate 5'-nucleotidase activity|thymidylate nucleotidase activity|dTMPase activity|deoxythymidylate phosphohydrolase activity|thymidylate 5'-nucleotidase activity				MetaCyc:THYMIDYLATE-5-PHOSPHATASE-RXN|EC:3.1.3.35|RHEA:11080									molecular_function											owl:Class	
GO:1990779	biolink:NamedThing	glycoprotein Ib-IX-V complex	A transmembrane signalling receptor complex found exclusively on platelets. Involved in haemostasis and thrombosis where it aids blood coagulation.	tmpzr1t_l9r_go_relaxed.owl	GPIb-IX-V complex|CD42|GPIb-V-IX complex					An example of this is GB1BA in human (P07359) in PMID:1730602 (inferred from direct assay).		bhm	2015-06-23T11:22:12Z					cellular_component											owl:Class	
GO:0106097	biolink:NamedThing	cellular response to ceramide	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ceramide stimulus.	tmpzr1t_l9r_go_relaxed.owl								hjd	2018-02-12T19:52:55Z					biological_process											owl:Class	
GO:0047620	biolink:NamedThing	acylglycerol kinase activity	Catalysis of the reaction: ATP + acylglycerol = ADP + acyl-sn-glycerol 3-phosphate.	tmpzr1t_l9r_go_relaxed.owl	monoglyceride kinase activity|sn-2-monoacylglycerol kinase activity|monoacylglycerol kinase activity|ATP:acylglycerol 3-phosphotransferase activity|monoacylglycerol kinase (phosphorylating)|MGK|monoglyceride phosphokinase activity				EC:2.7.1.94|MetaCyc:ACYLGLYCEROL-KINASE-RXN|RHEA:19293|Reactome:R-HSA-5696074									molecular_function											owl:Class	
GO:0102124	biolink:NamedThing	gibberellin A12 16alpha,17 epoxidase activity	Catalysis of the reaction: gibberellin A12 + O2 + H+ + NAD(P)H <=> 16alpha, 17-epoxy gibberellin A12 + H2O + NAD(P).	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-11387									molecular_function											owl:Class	
GO:0034972	biolink:NamedThing	histone H3-R26 methylation	The modification of histone H3 by addition of a methyl group to arginine at position 26 of the histone.	tmpzr1t_l9r_go_relaxed.owl	histone lysine H3 R26 methylation|histone H3 R26 methylation|histone H3R26me													biological_process											owl:Class	
GO:1901813	biolink:NamedThing	astaxanthin metabolic process	The chemical reactions and pathways involving astaxanthin.	tmpzr1t_l9r_go_relaxed.owl	astaxanthin metabolism							yaf	2013-01-22T10:36:59Z					biological_process											owl:Class	
GO:0070418	biolink:NamedThing	DNA-dependent protein kinase complex	A protein complex that is involved in the repair of DNA double-strand breaks and, in mammals, V(D)J recombination events. It consists of the DNA-dependent protein kinase catalytic subunit (DNA-PKcs) and the DNA end-binding heterodimer Ku.	tmpzr1t_l9r_go_relaxed.owl	DNA-PK-Ku antigen complex|DNA-PK complex|DNA-dependent protein kinase, DNA-end-binding complex													cellular_component											owl:Class	
GO:0033826	biolink:NamedThing	xyloglucan 4-glucosyltransferase activity	Catalysis of the transfer of a beta-D-glucosyl residue from UDP-glucose on to a glucose residue in xyloglucan, forming a beta-1,4-D-glucosyl-D-glucose linkage.	tmpzr1t_l9r_go_relaxed.owl	UDP-glucose:xyloglucan 1,4-beta-D-glucosyltransferase activity|uridine diphosphoglucose-xyloglucan 4beta-glucosyltransferase activity|xyloglucan glucosyltransferase activity|xyloglucan 4beta-D-glucosyltransferase activity|UDPglucose:xyloglucan 1,4-beta-D-glucosyltransferase activity				MetaCyc:2.4.1.168-RXN|EC:2.4.1.168									molecular_function											owl:Class	
GO:0019198	biolink:NamedThing	transmembrane receptor protein phosphatase activity	Combining with a signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: a phosphoprotein + H2O = a protein + phosphate.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0150092	biolink:NamedThing	regulation of synaptic scaling	A process that modulates synaptic scaling. Synaptic scaling is a form of synaptic plasticity, which entails uniform adjustments in the strength of all synapses on a cell in response to prolonged changes in the electrical activity of the cell.	tmpzr1t_l9r_go_relaxed.owl	regulation of homeostatic synaptic scaling|homeostatic synaptic scaling							bc	2018-08-09T16:27:28Z					biological_process											owl:Class	
GO:0050213	biolink:NamedThing	progesterone 5-alpha-reductase activity	Catalysis of the reaction: 5-alpha-pregnan-3,20-dione + NADP+ = progesterone + NADPH.	tmpzr1t_l9r_go_relaxed.owl	delta4-steroid 5alpha-reductase (progesterone)|progesterone 5a-reductase activity|progesterone 5alpha-reductase activity|5alpha-pregnan-3,20-dione:NADP+ 5-oxidoreductase activity|steroid 5-alpha-reductase activity				EC:1.3.1.30|MetaCyc:PROGESTERONE-5-ALPHA-REDUCTASE-RXN|RHEA:21952									molecular_function											owl:Class	
GO:0050186	biolink:NamedThing	phosphoadenylylsulfatase activity	Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + H2O = adenosine 3',5'-bisphosphate + sulfate.	tmpzr1t_l9r_go_relaxed.owl	3-phosphoadenosine 5-phosphosulfate sulfatase activity|phosphoadenylylsulphatase activity|3-phosphoadenylyl sulfatase activity|PAPS sulfatase activity|3'-phosphoadenylylsulfate sulfohydrolase activity				MetaCyc:PHOSPHOADENYLYLSULFATASE-RXN|RHEA:11232|EC:3.6.2.2									molecular_function											owl:Class	
GO:0097714	biolink:NamedThing	response to viscosity	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a viscosity stimulus.	tmpzr1t_l9r_go_relaxed.owl								pr	2016-08-23T14:32:46Z					biological_process											owl:Class	
GO:0052730	biolink:NamedThing	sarcosine N-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + sarcosine = S-adenosyl-L-homocysteine + N,N-dimethylglycine.	tmpzr1t_l9r_go_relaxed.owl	SDMT|S-adenosyl-L-methionine:N,N-sarcosine N-methyltransferase activity				RHEA:15453|EC:2.1.1.162|EC:2.1.1.156|MetaCyc:RXN-9679|EC:2.1.1.157|MetaCyc:RXN-7042|KEGG_REACTION:R07243|MetaCyc:R481-RXN			ai	2011-08-16T03:45:39Z					molecular_function											owl:Class	
GO:0010742	biolink:NamedThing	macrophage derived foam cell differentiation	The process in which a monocyte acquires the specialized features of a foam cell. A foam cell is a type of cell containing lipids in small vacuoles and typically seen in atherosclerotic lesions, as well as other conditions.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0070699	biolink:NamedThing	type II activin receptor binding	Binding to a type II activin receptor.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-06-04T04:16:26Z					molecular_function											owl:Class	
GO:2000566	biolink:NamedThing	positive regulation of CD8-positive, alpha-beta T cell proliferation	Any process that activates or increases the frequency, rate or extent of CD8-positive, alpha-beta T cell proliferation.	tmpzr1t_l9r_go_relaxed.owl								ebc	2011-04-03T09:03:24Z					biological_process											owl:Class	
GO:0103092	biolink:NamedThing	methylthioalkylmalate isomerase activity	Catalysis of the reaction: 2-(7'-methylthio)heptylmalate <=> 3-(7'-methylthio)heptylmalate.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXNQT-4176									molecular_function											owl:Class	
GO:0019389	biolink:NamedThing	glucuronoside metabolic process	The chemical reactions and pathways involving glucuronosides, any compound formed by combination in glycosidic linkage of a hydroxy compound with the anomeric carbon atom of a glucuronate.	tmpzr1t_l9r_go_relaxed.owl	glucuronoside metabolism|glucuronide metabolic process|glucuronide metabolism													biological_process											owl:Class	
GO:0010307	biolink:NamedThing	acetylglutamate kinase regulator activity	Modulates the enzyme activity of acetylglutamate kinase.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0044850	biolink:NamedThing	menstrual cycle	A type of ovulation cycle where the endometrium is shed if pregnancy does not occur.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Menstrual_cycle			jl	2014-07-16T13:51:29Z					biological_process											owl:Class	
GO:0097547	biolink:NamedThing	synaptic vesicle protein transport vesicle	A cytoplasmic vesicle composed of both tubulovesicular and clear core vesicles that transport synaptic vesicle-associated proteins. Proteins carried by synaptic vesicle protein transport vesicles (STVs) include synaptophysin, synapsin Ia, synaptotagmin and synaptobrevin/vesicle-associated membrane protein 2 (VAMP2). STVs are packaged via the trans-Golgi network before being transported through the axon.	tmpzr1t_l9r_go_relaxed.owl	STV					This term should not be confused with GO:0008021 'synaptic vesicle'. STVs and synaptic vesicles differ both functionally and morphologically. Functionally, STVs are transport vesicles that deliver synaptic vesicle proteins to synapses, while synaptic vesicles are responsible for transmitter release at synapses. Morphologically, synaptic vesicles are very homogeneous, while STVs are very heterogeneous in size and shape. STVs might be a precursor for synaptic vesicles.		pr	2013-12-20T09:22:03Z					cellular_component											owl:Class	
GO:0008154	biolink:NamedThing	actin polymerization or depolymerization	Assembly or disassembly of actin filaments by the addition or removal of actin monomers from a filament.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0030240	biolink:NamedThing	skeletal muscle thin filament assembly	The aggregation, arrangement and bonding together of proteins to form the actin-based thin filaments of myofibrils in skeletal muscle.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0061843	biolink:NamedThing	Sertoli cell barrier remodeling	The tissue remodeling process by which the Sertoli cell barrier is temporarily disrupted and reorganized to accommodate the transit of preleptotene spermatocytes at stage VIII of the epithelial cycle.	tmpzr1t_l9r_go_relaxed.owl	blood testis barrier restructuring|restructuring of blood-testis barrier|restructuring of BTB|Sertoli cell barrier restructuring|restructuring of SCB|SCB remodeling													biological_process											owl:Class	
GO:0099035	biolink:NamedThing	anchored component of spine apparatus membrane	The component of the spine apparatus membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0102637	biolink:NamedThing	5-aminolevulinate-CoA ligase activity	Catalysis of the reaction: 5-ammoniolevulinate + coenzyme A + ATP <=> 5-aminolevulinyl-CoA + AMP + diphosphoric acid.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-15714									molecular_function											owl:Class	
GO:0047217	biolink:NamedThing	sucrose-1,6-alpha-glucan 3(6)-alpha-glucosyltransferase activity	Catalysis of the reaction: sucrose + 1,6-alpha-D-glucosyl(n) = 1,6-alpha-D-glucosyl(n+1) + fructose.	tmpzr1t_l9r_go_relaxed.owl	GTF-S|sucrose:1,6-alpha-D-glucan 3-alpha- and 6-alpha-glucosyltransferase activity|sucrose:1,6-, 1,3-alpha-D-glucan 3-alpha- and 6-alpha-D-glucosyltransferase|sucrose:1,6-alpha-D-glucan 3(6)-alpha-D-glucosyltransferase activity|water-soluble-glucan synthase activity				MetaCyc:2.4.1.125-RXN|EC:2.4.1.125									molecular_function											owl:Class	
GO:0102804	biolink:NamedThing	oripavine 6-O-demethylase activity	Catalysis of the reaction: oripavine + 2-oxoglutarate + O2 <=> morphinone + formaldehyde + succinate + carbon dioxide.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-8151|EC:1.14.11.31									molecular_function											owl:Class	
GO:0033938	biolink:NamedThing	1,6-alpha-L-fucosidase activity	Catalysis of the hydrolysis of (1->6) linkages between alpha-L-fucose and N-acetyl-D-glucosamine in glycopeptides such as immunoglobulin G glycopeptide and fucosyl-asialo-agalacto-fetuin.	tmpzr1t_l9r_go_relaxed.owl	1,6-L-fucosyl-N-acetyl-D-glucosaminylglycopeptide fucohydrolase activity				MetaCyc:3.2.1.127-RXN|EC:3.2.1.127									molecular_function											owl:Class	
GO:1903142	biolink:NamedThing	positive regulation of establishment of endothelial barrier	Any process that activates or increases the frequency, rate or extent of establishment of endothelial barrier.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of establishment of endothelial barrier|up regulation of establishment of endothelial barrier|upregulation of establishment of endothelial barrier|activation of establishment of endothelial barrier							als	2014-07-01T12:12:52Z					biological_process											owl:Class	
GO:1901552	biolink:NamedThing	positive regulation of endothelial cell development	Any process that activates or increases the frequency, rate or extent of endothelial cell development.	tmpzr1t_l9r_go_relaxed.owl	upregulation of endothelial cell development|activation of endothelial cell development|up regulation of endothelial cell development|up-regulation of endothelial cell development							pr	2012-10-30T12:59:58Z					biological_process											owl:Class	
GO:0034980	biolink:NamedThing	FHL2-CREB complex	A protein complex that contains CREB and FHL2, and is involved in transcriptional regulation.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0019333	biolink:NamedThing	denitrification pathway	The reduction of nitrate to dinitrogen by four reactions; each intermediate is transformed to the next lower oxidation state; also part of cellular bioenergetics; the nitrogen compounds can serve as terminal acceptors for electron transport phosphorylation in place of oxygen.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:DENITRIFICATION-PWY									biological_process											owl:Class	
GO:0070334	biolink:NamedThing	alpha6-beta4 integrin-laminin 5 complex	A protein complex that consists of an alpha6-beta4 integrin complex bound to laminin 5.	tmpzr1t_l9r_go_relaxed.owl	alpha6-beta4 integrin-laminin-332 complex|ITGA6-ITGB4-LAMA5 complex													cellular_component											owl:Class	
GO:0061735	biolink:NamedThing	DNM1L-mediated stimulation of mitophagy in response to mitochondrial depolarization	A positive regulation of the macromitophagy pathway that is triggered by mitochondrial depolarization and requires the function of a DNM1L-family molecule.	tmpzr1t_l9r_go_relaxed.owl	dynamin-like protein-mediated stimulation of mitophagy in response to mitochondrial depolarization							dph	2015-09-14T14:00:43Z					biological_process											owl:Class	
GO:0018001	biolink:NamedThing	N-terminal peptidyl-valine acetylation	The acetylation of the N-terminal tyrosine of proteins to form the derivative N-acetyl-L-valine.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0054									biological_process											owl:Class	
GO:0071401	biolink:NamedThing	cellular response to triglyceride	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a triglyceride stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to triacylglyceride|cellular response to triacylglycerol							mah	2009-12-11T04:40:56Z					biological_process											owl:Class	
GO:0047977	biolink:NamedThing	hepoxilin-epoxide hydrolase activity	Catalysis of the reaction: (5Z,9E,14Z)-(8x,11R,12S)-11,12-epoxy-8-hydroxyicosa-5,9,14-trienoate + H2O = (5Z,9E,14Z)-(8x,11x,12S)-8,11,12-trihydroxyicosa-5,9,14-trienoate.	tmpzr1t_l9r_go_relaxed.owl	(5Z,9E,14Z)-(8xi,11R,12S)-11,12-epoxy-8-hydroxyicosa-5,9,14-trienoate hydrolase activity|hepoxilin A3 hydrolase activity|hepoxilin epoxide hydrolase activity|hepoxilin A(3) hydrolase activity|hepoxylin hydrolase activity				MetaCyc:HEPOXILIN-EPOXIDE-HYDROLASE-RXN|RHEA:16665|Reactome:R-HSA-2161949|EC:3.3.2.7									molecular_function											owl:Class	
GO:2001043	biolink:NamedThing	positive regulation of septum digestion after cytokinesis	Any process that activates or increases the frequency, rate or extent of the process of physically separating the septal cell wall material by enzymatic digestion, that occurs after daughter cells are separated by cytokinesis.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of cell separation after cytokinesis|positive regulation of cytokinetic cell separation							mcc	2011-08-30T05:16:57Z					biological_process											owl:Class	
GO:0004515	biolink:NamedThing	nicotinate-nucleotide adenylyltransferase activity	Catalysis of the reaction: ATP + nicotinate ribonucleotide = diphosphate + deamido-NAD+.	tmpzr1t_l9r_go_relaxed.owl	ATP:nicotinate-ribonucleotide adenylyltransferase activity|ATP:nicotinate-nucleotide adenylyltransferase activity|deamidonicotinamide adenine dinucleotide pyrophosphorylase activity|deamido-NAD+ pyrophosphorylase activity|nicotinate mononucleotide adenylyltransferase activity|nicotinic acid mononucleotide adenylyltransferase|deamido-NAD(+) diphosphorylase activity|deamido-NAD(+) pyrophosphorylase activity|NaMN-ATase activity				Reactome:R-HSA-200512|EC:2.7.7.18|Reactome:R-HSA-197235|MetaCyc:NICONUCADENYLYLTRAN-RXN|RHEA:22860|Reactome:R-HSA-200474									molecular_function											owl:Class	
GO:0048197	biolink:NamedThing	Golgi membrane coat protein complex assembly	The aggregation, arrangement and bonding together of priming complexes to form a coat on a Golgi membrane. Priming complexes associate laterally and additional coat proteins are recruited from the cytosol to the forming coat. Cargo proteins diffuse into the budding site and become trapped by their interactions with the coat.	tmpzr1t_l9r_go_relaxed.owl	dictyosome membrane binding by cytosolic coat proteins|dictyosome membrane bud coat oligomerisation|Golgi membrane bud coat oligomerisation													biological_process											owl:Class	
GO:0004876	biolink:NamedThing	complement component C3a receptor activity	Combining with the C3a product of the complement cascade and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	C3a anaphylatoxin receptor activity											GO:0004943		molecular_function											owl:Class	
GO:0102592	biolink:NamedThing	delphinidin 7-O-(6-O-(4-O-(glucosyl)-oxybenzoyl)-glucoside) acyltransferase (acyl-glucose dependent activity	Catalysis of the reaction: delphinidin 3-O-rutinoside-7-O-(6-O-(4-O-(glucosyl)-oxybenzoyl)-glucoside) + 1-O-4-hydroxybenzoyl-beta-D-glucose <=> violdelphin + beta-D-glucose.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-15354									molecular_function											owl:Class	
GO:0102660	biolink:NamedThing	caffeoyl-CoA:shikimate O-(hydroxycinnamoyl)transferase activity	Catalysis of the reaction: caffeoylshikimate + coenzyme A <=> caffeoyl-CoA + shikimate.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-2621									molecular_function											owl:Class	
GO:0102634	biolink:NamedThing	1,3,6,8-tetrahydroxynaphthalene monooxygenase (quinone-forming) activity	Catalysis of the reaction: naphthalene-1,3,6,8-tetrol + O2 <=> flaviolin-2-olate + H2O + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-15586									molecular_function											owl:Class	
GO:0019140	biolink:NamedThing	inositol 3-kinase activity	Catalysis of the reaction: ATP + myo-inositol = ADP + 1D-myo-inositol 3-phosphate.	tmpzr1t_l9r_go_relaxed.owl	myoinositol kinase activity|myo-inositol 1-kinase activity|myo-inositol 3-kinase activity|inositol-1-kinase (phosphorylating)|inositol 1-kinase activity|ATP:myo-inositol 1-phosphotransferase activity				EC:2.7.1.64|RHEA:21804|MetaCyc:MYO-INOSITOL-1-KINASE-RXN									molecular_function											owl:Class	
GO:0009276	biolink:NamedThing	Gram-negative-bacterium-type cell wall	The peptidoglycan layer of the Gram-negative cell envelope. In Gram-negative cells the peptidoglycan is relatively thin (1-2nm) and is linked to the outer membrane by lipoproteins. In Gram-negative cells the peptidoglycan is too thin to retain the primary stain in the Gram staining procedure and therefore cells appear red after Gram stain.	tmpzr1t_l9r_go_relaxed.owl	1-2nm peptidoglycan-based cell wall|cell wall inner membrane													cellular_component											owl:Class	
GO:1903032	biolink:NamedThing	negative regulation of microtubule plus-end binding	Any process that stops, prevents or reduces the frequency, rate or extent of microtubule plus-end binding.	tmpzr1t_l9r_go_relaxed.owl	inhibition of microtubule plus-end binding|down regulation of microtubule plus-end binding|down-regulation of microtubule plus-end binding|downregulation of microtubule plus-end binding							hjd	2014-05-16T18:38:32Z					biological_process											owl:Class	
GO:0034900	biolink:NamedThing	3-(N-formyl)-formiminopyruvate hydrolase activity	Catalysis of the reaction: 3-(N-formyl)-formiminopyruvate + H2O = 3-formiminopyruvate + formate.	tmpzr1t_l9r_go_relaxed.owl					EC:3.5.99.-|UM-BBD_reactionID:r1399									molecular_function											owl:Class	
GO:0043908	biolink:NamedThing	Ser(Gly)-tRNA(Ala) hydrolase activity	Catalysis of the hydrolysis of misacylated Ser-tRNA(Ala) and Gly-tRNA(Ala).	tmpzr1t_l9r_go_relaxed.owl	Ser(Gly)-tRNAAla hydrolase activity				EC:3.1.1.-									molecular_function											owl:Class	
GO:0072305	biolink:NamedThing	negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis	Any process that reduces the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the metanephros.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of mesenchymal stem cell apoptosis involved in metanephric nephron morphogenesis|negative regulation of mesenchymal stem cell apoptotic process involved in metanephric nephron morphogenesis							mah	2010-04-09T05:03:41Z					biological_process											owl:Class	
GO:1904614	biolink:NamedThing	response to biphenyl	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biphenyl stimulus.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-08-27T19:08:43Z					biological_process											owl:Class	
GO:0008899	biolink:NamedThing	homoserine O-succinyltransferase activity	Catalysis of the reaction: L-homoserine + succinyl-CoA = O-succinyl-L-homoserine + CoA.	tmpzr1t_l9r_go_relaxed.owl	succinyl-CoA:L-homoserine O-succinyltransferase activity|homoserine succinyltransferase activity|homoserine O-transsuccinylase activity				MetaCyc:HOMSUCTRAN-RXN|RHEA:22008|KEGG_REACTION:R01777|EC:2.3.1.46									molecular_function											owl:Class	
GO:0034786	biolink:NamedThing	9-fluorenone-3,4-dioxygenase activity	Catalysis of the reaction: 9-fluorenone + O2 + 2 H+ + 2 e- = 1-hydro-1,1a-dihydroxy-9-fluorenone.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r1039									molecular_function											owl:Class	
GO:0016528	biolink:NamedThing	sarcoplasm	The cytoplasm of a muscle cell; includes the sarcoplasmic reticulum.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Sarcoplasm									cellular_component											owl:Class	
GO:0016309	biolink:NamedThing	1-phosphatidylinositol-5-phosphate 4-kinase activity	Catalysis of the reaction: ATP + 1-phosphatidyl-1D-myo-inositol 5-phosphate = ADP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate.	tmpzr1t_l9r_go_relaxed.owl	1-phosphatidylinositol-5-phosphate kinase|PIP4K|ATP:1-phosphatidyl-1D-myo-inositol-5-phosphate 4-phosphotransferase activity|type II PIP kinase activity				Reactome:R-HSA-1675776|MetaCyc:2.7.1.149-RXN|RHEA:12280|EC:2.7.1.149|Reactome:R-HSA-6811522									molecular_function											owl:Class	
GO:0047412	biolink:NamedThing	N-(long-chain-acyl)ethanolamine deacylase activity	Catalysis of the reaction: H2O + N-(long-chain-acyl)ethanolamine = ethanolamine + a fatty acid.	tmpzr1t_l9r_go_relaxed.owl	acylethanolamine amidase activity|N-(long-chain-acyl)ethanolamine amidohydrolase activity|N-acylethanolamine amidohydrolase activity				RHEA:17505|MetaCyc:3.5.1.60-RXN|EC:3.5.1.60									molecular_function											owl:Class	
GO:0071749	biolink:NamedThing	polymeric IgA immunoglobulin complex	A protein complex composed of two, three, or four monomeric IgA immunoglobulin complexes linked through both direct disulfide bonds and through disulfide binded monomers of J chain acting as a bridge. Each IgA monomer consists of two identical immunoglobulin heavy chains of an IgA isotype and two identical immunoglobulin light chains, held together by disulfide bonds. Dimeric IgA is sometimes complexed additionally with secretory component, and present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.	tmpzr1t_l9r_go_relaxed.owl	pIgA1 antibody|polymeric IgA antibody|polymeric IgA1 antibody|pIgA antibody					Note that an IgA immunoglobulin complex has the function of antigen binding if a suitable antigen is available. Dimeric IgA is by far the most common form of polymeric IgA. In human only the IgA1 isotype is capable of a polymeric forms.		mah	2010-03-24T01:44:53Z					cellular_component											owl:Class	
GO:0003195	biolink:NamedThing	tricuspid valve formation	The developmental process pertaining to the initial formation of the tricuspid valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-10-08T01:14:40Z					biological_process											owl:Class	
GO:0102299	biolink:NamedThing	linolenate 9R-lipoxygenase activity	Catalysis of the reaction: alpha-linolenate + O2 <=> (9R,10E,12Z,15Z)-9-hydroperoxyoctadeca-10,12,15-trienoate.	tmpzr1t_l9r_go_relaxed.owl					EC:1.13.11.61|RHEA:31687|MetaCyc:RXN-12759									molecular_function											owl:Class	
GO:0031914	biolink:NamedThing	negative regulation of synaptic plasticity	A process that decreases synaptic plasticity, the ability of synapses to change as circumstances require. They may alter function, such as increasing or decreasing their sensitivity, or they may increase or decrease in actual numbers.	tmpzr1t_l9r_go_relaxed.owl	downregulation of synaptic plasticity|inhibition of synaptic plasticity|down regulation of synaptic plasticity|down-regulation of synaptic plasticity													biological_process											owl:Class	
GO:0010021	biolink:NamedThing	amylopectin biosynthetic process	The chemical reactions and pathways resulting in the formation of amylopectin, the (1->4) linked alpha glucose units with alpha-(1->6) linkages.	tmpzr1t_l9r_go_relaxed.owl	amylopectin formation|amylopectin synthesis|amylopectin biosynthesis|amylopectin anabolism													biological_process											owl:Class	
GO:0031316	biolink:NamedThing	extrinsic component of nuclear outer membrane	The component of a nuclear outer membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.	tmpzr1t_l9r_go_relaxed.owl	extrinsic to nuclear outer membrane													cellular_component											owl:Class	
GO:0047892	biolink:NamedThing	flavone apiosyltransferase activity	Catalysis of the reaction: UDP-apiose + 7-O-beta-D-glucosyl-5,7,4'-trihydroxyflavone = UDP + 7-O-(beta-D-apiofuranosyl-1,2-beta-D-glucosyl)-5,7,4'-trihydroxyflavone.	tmpzr1t_l9r_go_relaxed.owl	UDP-apiose:5,4'-dihydroxyflavone 7-O-beta-D-glucoside 2''-O-beta-D-apiofuranosyltransferase activity|uridine diphosphoapiose-flavone apiosyltransferase activity|UDP-apiose:7-O-(beta-D-glucosyl)-flavone apiosyltransferase activity				MetaCyc:FLAVONE-APIOSYLTRANSFERASE-RXN|RHEA:19153|EC:2.4.2.25									molecular_function											owl:Class	
GO:0042794	biolink:NamedThing	plastid rRNA transcription	The synthesis of ribosomal RNA (rRNA) from a plastid DNA template, usually by a specific plastid RNA polymerase.	tmpzr1t_l9r_go_relaxed.owl	rRNA transcription from plastid promoter	https://github.com/geneontology/go-ontology/issues/14854												biological_process											owl:Class	
GO:0021967	biolink:NamedThing	corticospinal neuron axon guidance through the cerebral cortex	The process in which the migration of an axon growth cone of a pyramidal cell that is part of the corticospinal tract is directed from its cell body in layer V through the cerebral cortex in response to a combination of attractive and repulsive cues.	tmpzr1t_l9r_go_relaxed.owl	corticospinal neuron axon pathfinding through the cerebral cortex													biological_process											owl:Class	
GO:1990919	biolink:NamedThing	proteasome-nuclear membrane anchor activity	The binding activity of a molecule that brings together a proteasome complex and a nuclear inner membrane, to maintain the nuclear membrane localization of the proteasome.	tmpzr1t_l9r_go_relaxed.owl	nuclear membrane proteasome tether activity|nuclear membrane proteasome tether|nuclear membrane-proteasome anchor activity|tethering factor for nuclear proteasome|nuclear membrane-proteasome tether activity|nuclear membrane proteasome adaptor|nuclear membrane proteasome anchor	https://github.com/geneontology/go-ontology/issues/19119						vw	2015-12-14T14:01:45Z					molecular_function											owl:Class	
GO:0002499	biolink:NamedThing	proteolysis within endosome associated with antigen processing and presentation	The hydrolysis of a peptide bond or bonds within a protein by endosomal resident proteases contributing to antigen processing and presentation.	tmpzr1t_l9r_go_relaxed.owl	endosomal proteolysis associated with antigen processing and presentation													biological_process											owl:Class	
GO:0097333	biolink:NamedThing	response to olanzapine	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an olanzapine stimulus.	tmpzr1t_l9r_go_relaxed.owl								pr	2012-06-12T11:00:04Z					biological_process											owl:Class	
GO:0030474	biolink:NamedThing	spindle pole body duplication	Construction of a new spindle pole body.	tmpzr1t_l9r_go_relaxed.owl	spindle pole body duplication in cytoplasm|spindle pole body biogenesis|spindle pole body biosynthesis|spindle pole body replication|spindle pole body assembly|spindle pole body duplication associated with nuclear envelope|spindle pole body formation											GO:0007103|GO:0031046		biological_process											owl:Class	
GO:0031962	biolink:NamedThing	mineralocorticoid receptor binding	Binding to a mineralocorticoid receptor.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0120232	biolink:NamedThing	prenyl-FMNH2 biosynthetic process	The chemical reactions and pathways resulting in prenyl-FMNH2, an essential cofactor for the decarboxylase enzymes UbiD and Fdc1.	tmpzr1t_l9r_go_relaxed.owl	prenylated FMNH2 anabolism|prenyl-FMNH2 synthesis|prenylated FMNH2 biosynthetic process|prenyl-FMNH2 biosynthesis|prenylated FMNH2 formation|prenyl-FMNH2 anabolism|prenylated FMNH2 synthesis|prenyl-FMNH2 formation|prenylated FMNH2 biosynthesis	https://github.com/geneontology/go-ontology/issues/19244						krc	2020-06-30T19:09:11Z					biological_process											owl:Class	
GO:1990964	biolink:NamedThing	actin cytoskeleton-regulatory complex	A protein complex probably required for the internalization of endosomes during actin-coupled endocytosis. Links the site of endocytosis to the cell membrane-associated actin cytoskeleton, coordinating ARP2/3 stimulation at the later stages of endocytosis. Present in the late endocytic coat.	tmpzr1t_l9r_go_relaxed.owl						An example of this is Pan1 in Saccharomyces cerevisiae (UniProt ID P32521) in PMID:10594004 (inferred from direct assay).		bhm	2016-06-09T12:18:30Z					cellular_component											owl:Class	
GO:0047482	biolink:NamedThing	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate-L-lysine ligase activity	Catalysis of the reaction: L-lysine + ATP + UDP-N-acetylmuramoyl-L-alanyl-D-glutamate = ADP + 2 H(+) + phosphate + UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysine.	tmpzr1t_l9r_go_relaxed.owl	UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysine synthetase activity|UPD-MurNAc-L-Ala-D-Glu:L-Lys ligase activity|MurE synthetase activity|uridine diphospho-N-acetylmuramoylalanyl-D-glutamyllysine synthetase activity|L-lysine-adding enzyme activity|UDP-N-acetylmuramoyl-L-alanyl-D-glutamate:L-lysine gamma-ligase (ADP-forming)				EC:6.3.2.7|MetaCyc:6.3.2.7-RXN|RHEA:17969|KEGG_REACTION:R02786									molecular_function											owl:Class	
GO:0072375	biolink:NamedThing	medium-term memory	The memory process that deals with the storage, retrieval and modification of information received at a time ago that is intermediate between that of short and long term memory (30min - 7hrs in Drosophila melanogaster).	tmpzr1t_l9r_go_relaxed.owl	MTM|middle-term memory							mah	2010-11-22T11:26:54Z					biological_process											owl:Class	
GO:1903283	biolink:NamedThing	negative regulation of glutathione peroxidase activity	Any process that stops, prevents or reduces the frequency, rate or extent of glutathione peroxidase activity.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of glutathione:hydrogen-peroxide oxidoreductase activity|down regulation of non-selenium glutathione peroxidase activity|down-regulation of glutathione peroxidase activity|down regulation of glutathione:hydrogen-peroxide oxidoreductase activity|downregulation of glutathione peroxidase activity|down regulation of selenium-glutathione peroxidase activity|down regulation of GSH peroxidase activity|down-regulation of selenium-glutathione peroxidase activity|down-regulation of non-selenium glutathione peroxidase activity|negative regulation of selenium-glutathione peroxidase activity|downregulation of reduced glutathione peroxidase activity|downregulation of non-selenium glutathione peroxidase activity|inhibition of selenium-glutathione peroxidase activity|inhibition of GSH peroxidase activity|downregulation of glutathione:hydrogen-peroxide oxidoreductase activity|negative regulation of reduced glutathione peroxidase activity|negative regulation of non-selenium glutathione peroxidase activity|down-regulation of GSH peroxidase activity|down-regulation of reduced glutathione peroxidase activity|inhibition of reduced glutathione peroxidase activity|down regulation of glutathione peroxidase activity|down regulation of reduced glutathione peroxidase activity|down-regulation of glutathione:hydrogen-peroxide oxidoreductase activity|negative regulation of GSH peroxidase activity|inhibition of non-selenium glutathione peroxidase activity|inhibition of glutathione:hydrogen-peroxide oxidoreductase activity|inhibition of glutathione peroxidase activity|downregulation of selenium-glutathione peroxidase activity|downregulation of GSH peroxidase activity							bf	2014-08-11T13:14:22Z					biological_process											owl:Class	
GO:0061752	biolink:NamedThing	telomeric repeat-containing RNA binding	Binding to long non-coding RNA molecules transcribed from subtelomeric regions in most eukaryotes. Telomeric repeat-containing RNA (TERRA) molecules consist of subtelomeric-derived sequences and G-rich telomeric repeats.	tmpzr1t_l9r_go_relaxed.owl	TERRA binding							dph	2015-11-13T07:55:06Z					molecular_function											owl:Class	
GO:0009186	biolink:NamedThing	deoxyribonucleoside diphosphate metabolic process	The chemical reactions and pathways involving a deoxyribonucleoside diphosphate, a compound consisting of a nucleobase linked to a deoxyribose sugar esterified with diphosphate on the sugar.	tmpzr1t_l9r_go_relaxed.owl	deoxyribonucleoside diphosphate metabolism													biological_process											owl:Class	
GO:0045320	biolink:NamedThing	chloroplast proton-transporting ATP synthase complex	A proton-transporting ATP synthase complex found in the chloroplast thylakoid membrane; it catalyzes the phosphorylation of ADP to ATP during photo-phosphorylation.	tmpzr1t_l9r_go_relaxed.owl	chloroplast hydrogen-translocating F-type ATPase complex|hydrogen-translocating F-type ATPase complex|chloroplast proton-transporting F-type ATPase complex													cellular_component											owl:Class	
GO:0071754	biolink:NamedThing	IgM immunoglobulin complex, circulating	A polymer of five or six IgM core units each composed of two identical immunoglobulin heavy chains of the IgM isotype and two identical immunoglobulin light chains, held together by disulfide bonds; the individual IgM core units are held together via disulfide bonds with a single J chain polypeptide acting as a bridge between two of the polymeric units. Circulating IgM is present in the extracellular space, in mucosal areas or other tissues, or in the blood or lymph.	tmpzr1t_l9r_go_relaxed.owl	IgM antibody					Note that an IgM immunoglobulin complex has the function of antigen binding if a suitable antigen is available.		mah	2010-03-24T01:44:53Z					cellular_component											owl:Class	
GO:0039660	biolink:NamedThing	structural constituent of virion	The action of a molecule that contributes to the structural integrity of a virion.	tmpzr1t_l9r_go_relaxed.owl	viral matrix protein							bf	2013-07-22T16:43:41Z					molecular_function											owl:Class	
GO:0099112	biolink:NamedThing	microtubule polymerization based protein transport	The transport of a protein driven by polymerization of a microtubule to which it is attached.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0048531	biolink:NamedThing	beta-1,3-galactosyltransferase activity	Catalysis of the transfer of a galactose residue from a donor molecule to an oligosaccharide, forming a beta-1,3-linkage.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0036305	biolink:NamedThing	ameloblast differentiation	The process in which a relatively unspecialized cell acquires specialized features of an ameloblast, a cylindrical epithelial cell in the innermost layer of the enamel organ.	tmpzr1t_l9r_go_relaxed.owl								bf	2012-08-08T13:49:15Z					biological_process											owl:Class	
GO:0036070	biolink:NamedThing	light-independent bacteriochlorophyll biosynthetic process	The chemical reactions and pathways resulting in the formation of a bacteriochlorophyll, which occur in the absence of light. Bacteriochlorophylls are any of the chlorophylls of photosynthetic bacteria; they differ structurally from the chlorophylls of higher plants.	tmpzr1t_l9r_go_relaxed.owl	light independent bacteriochlorophyll biosynthetic process|light-independent bacteriochlorophyll synthesis|light-independent bacteriochlorophyll formation|light-independent bacteriochlorophyll biosynthesis|light-independent bacteriochlorophyll anabolism							bf	2011-12-15T04:46:25Z					biological_process											owl:Class	
GO:0017061	biolink:NamedThing	S-methyl-5-thioadenosine phosphorylase activity	Catalysis of the reaction: 5'-methylthioadenosine + phosphate = adenine + 5-methylthio-D-ribose 1-phosphate.	tmpzr1t_l9r_go_relaxed.owl	MeSAdo phosphorylase activity|5'-deoxy-5'-methylthioadenosine phosphorylase activity|5'-methylthioadenosine:phosphate methylthio-D-ribosyl-transferase activity|methylthioadenosine phosphorylase activity|MTA phosphorylase activity|methylthioadenosine nucleoside phosphorylase activity|S-methyl-5-thioadenosine:phosphate S-methyl-5-thio-alpha-D-ribosyl-transferase activity|MTAPase activity|5'-methylthioadenosine phosphorylase activity|MeSAdo/Ado phosphorylase activity				MetaCyc:5-METHYLTHIOADENOSINE-PHOSPHORYLASE-RXN|Reactome:R-HSA-1237160|EC:2.4.2.28|RHEA:11852									molecular_function											owl:Class	
GO:0071835	biolink:NamedThing	mating pheromone secretion involved in regulation of conjugation	The regulated release of a mating pheromone, a peptide hormone that induces a behavioral or physiological response(s) from a responding organism or cell, that regulates the union or introduction of genetic information from compatible mating types that results in a genetically different individual. Conjugation requires direct cellular contact between the organisms.	tmpzr1t_l9r_go_relaxed.owl	mating-type pheromone secretion involved in conjugation							mah	2010-09-09T11:23:19Z					biological_process											owl:Class	
GO:0009346	biolink:NamedThing	ATP-independent citrate lyase complex	Citrate lyase is a multienzyme complex with three constituents: the alpha subunit, citrate-ACP transferase; the beta subunit, citryl-ACP lyase; and the gamma subunit, an acyl-carrier protein which also carries the prosthetic group components. All three subunits are required for citrate lyase enzyme activity. This enzyme has only been found in bacteria.	tmpzr1t_l9r_go_relaxed.owl	citrate synthase complex|citrate lyase complex	https://github.com/geneontology/go-ontology/issues/21028			MetaCyc:ACECITLY-CPLX	Note that this complex has only been found in bacteria. For eukaryotic cytrate lyases, consider GO:0140615 ; ATP-dependent citrate lyase complex.								cellular_component											owl:Class	
GO:0140031	biolink:NamedThing	phosphorylation-dependent protein binding	Binding to a protein upon phosphorylation of the target protein.	tmpzr1t_l9r_go_relaxed.owl						This term should only be used when the binding is shown to require phosphorylation of the target protein: the interaction needs to be tested with and without the PTM. The binding does not need to be at the site of phosphorylation. It may be that the phosphorylation causes a conformational change that allows binding of the protein to another region; this type of phosphorylation-dependent protein binding is valid for annotation to this term.		pg	2017-05-17T15:15:19Z					molecular_function											owl:Class	
GO:0044073	biolink:NamedThing	modulation by symbiont of host translation	The process in which a symbiont organism effects a change in translation, the chemical reactions and pathways resulting in the formation of a protein, in its host organism.	tmpzr1t_l9r_go_relaxed.owl	modification by symbiont of host translation|regulation by symbiont of host translation|modulation of host translation by symbiont													biological_process											owl:Class	
GO:0004168	biolink:NamedThing	dolichol kinase activity	Catalysis of the reaction: CTP + dolichol = CDP + dolichyl phosphate.	tmpzr1t_l9r_go_relaxed.owl	dolichol phosphokinase activity|CTP:dolichol O-phosphotransferase activity				MetaCyc:DOLICHOL-KINASE-RXN|RHEA:13133|Reactome:R-HSA-4755600|EC:2.7.1.108|Reactome:R-HSA-446195									molecular_function											owl:Class	
GO:0000159	biolink:NamedThing	protein phosphatase type 2A complex	A protein complex that has protein serine/threonine phosphatase activity that is polycation-stimulated (PCS), being directly stimulated by protamine, polylysine, or histone H1; it constitutes a subclass of several enzymes activated by different histones and polylysine, and consists of catalytic, scaffolding, and regulatory subunits. The catalytic and scaffolding subunits form the core enzyme, and the holoenzyme also includes the regulatory subunit.	tmpzr1t_l9r_go_relaxed.owl	PP2A-pi|PP2A complex|PP2a-protector|protein phosphatase 2 complex													cellular_component											owl:Class	
GO:1905542	biolink:NamedThing	negative regulation of L-arginine import across plasma membrane	Any process that stops, prevents or reduces the frequency, rate or extent of L-arginine import across plasma membrane.	tmpzr1t_l9r_go_relaxed.owl	inhibition of L-arginine import into cell|negative regulation of L-arginine import into cell|downregulation of L-arginine import into cell|down regulation of L-arginine import into cell							mah	2014-03-31T14:30:46Z			GO:1902827		biological_process											owl:Class	
GO:0007225	biolink:NamedThing	patched ligand maturation	The posttranslational modification of members of the Hedgehog family of signaling proteins in order for Hedgehog to exert its biological activity. These modifications include cleavage of its signal sequence, autocatalytic protein cleavage and the attachment of sterol groups.	tmpzr1t_l9r_go_relaxed.owl	hh protein processing|patched ligand processing|Hedgehog protein processing													biological_process											owl:Class	
GO:0071316	biolink:NamedThing	cellular response to nicotine	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nicotine stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-12-10T05:05:05Z					biological_process											owl:Class	
GO:1901130	biolink:NamedThing	gentamycin biosynthetic process	The chemical reactions and pathways resulting in the formation of gentamycin.	tmpzr1t_l9r_go_relaxed.owl	gentamycin anabolism|gentamycin formation|gentamycin synthesis|gentamycin biosynthesis							yaf	2012-07-11T03:26:59Z					biological_process											owl:Class	
GO:0097160	biolink:NamedThing	polychlorinated biphenyl binding	Binding to a polychlorinated biphenyl (PCB), a biphenyl compound containing between 2 and 10 chlorine atoms attached to the two benzene rings.	tmpzr1t_l9r_go_relaxed.owl	polychlorobiphenyl binding|PCB binding							pr	2011-09-23T02:33:22Z					molecular_function											owl:Class	
GO:0099167	biolink:NamedThing	integral component of postsynaptic specialization membrane of symmetric synapse	The component of the postsynaptic specialization membrane of a symmetric synapse consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.	tmpzr1t_l9r_go_relaxed.owl								dos	2017-09-10T11:58:46Z					cellular_component											owl:Class	
GO:0048040	biolink:NamedThing	UDP-glucuronate decarboxylase activity	Catalysis of the reaction: H(+) + UDP-alpha-D-glucuronate = CO(2) + UDP-alpha-D-xylose.	tmpzr1t_l9r_go_relaxed.owl	UDP-D-glucuronate carboxy-lyase activity|UDP-D-glucuronate carboxy-lyase (UDP-D-xylose-forming)|uridine-diphosphoglucuronate decarboxylase activity|UDPglucuronate decarboxylase activity|UDP-glucuronic acid decarboxylase activity				RHEA:23916|MetaCyc:UDP-GLUCURONATE-DECARBOXYLASE-RXN|EC:4.1.1.35|KEGG_REACTION:R01384									molecular_function											owl:Class	
GO:0018311	biolink:NamedThing	peptidyl-N4-hydroxymethyl-L-asparagine biosynthetic process from peptidyl-asparagine	The chemical reactions and pathways resulting in the formation of N4-hydroxymethyl-L-asparagine from other compounds, including peptidyl-asparagine.	tmpzr1t_l9r_go_relaxed.owl	peptidyl-N4-hydroxymethyl-L-asparagine synthesis from peptidyl-asparagine|peptidyl-N4-hydroxymethyl-L-asparagine formation from peptidyl-asparagine|peptidyl-N4-hydroxymethyl-L-asparagine anabolism from peptidyl-asparagine				RESID:AA0236									biological_process											owl:Class	
GO:0018944	biolink:NamedThing	tri-n-butyltin metabolic process	The chemical reactions and pathways involving tri-n-butyltin, an organometallic compound composed of three butyl chains attached to a tin atom. Tri-n-butyltin is used as an antifouling agent in ship bottom paints and can be toxic to many marine organisms.	tmpzr1t_l9r_go_relaxed.owl	tri-n-butyltin metabolism				UM-BBD_pathwayID:tbt									biological_process											owl:Class	
GO:0018943	biolink:NamedThing	organotin metabolic process	The chemical reactions and pathways involving organotin, an organic compound containing a tin atom.	tmpzr1t_l9r_go_relaxed.owl	organotin metabolism													biological_process											owl:Class	
GO:0035644	biolink:NamedThing	phosphoanandamide dephosphorylation	The process of removing one or more phosphate groups from a phosphorylated anandamide.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-01-21T02:14:04Z					biological_process											owl:Class	
GO:0017146	biolink:NamedThing	NMDA selective glutamate receptor complex	An assembly of four or five subunits which form a structure with an extracellular N-terminus and a large loop that together form the ligand binding domain. The C-terminus is intracellular. The ionotropic glutamate receptor complex itself acts as a ligand gated ion channel; on binding glutamate, charged ions pass through a channel in the center of the receptor complex. NMDA receptors are composed of assemblies of NR1 subunits (Figure 3) and NR2 subunits, which can be one of four separate gene products (NR2A-D). Expression of both subunits are required to form functional channels. The glutamate binding domain is formed at the junction of NR1 and NR2 subunits. NMDA receptors are permeable to calcium ions as well as being permeable to other ions. Thus NMDA receptor activation leads to a calcium influx into the post-synaptic cells, a signal thought to be crucial for the induction of NMDA-receptor dependent LTP and LTD.	tmpzr1t_l9r_go_relaxed.owl	N-methyl-D-aspartate selective glutamate receptor complex|NMDA-selective glutamate receptor													cellular_component											owl:Class	
GO:0098958	biolink:NamedThing	retrograde axonal transport of mitochondrion	The directed movement of mitochondria along microtubules in axons towards the cell body and away from the presynapse.	tmpzr1t_l9r_go_relaxed.owl	retrograde axon transport of mitochondria													biological_process											owl:Class	
GO:0150025	biolink:NamedThing	oxidised low-density lipoprotein particle receptor activity	Combining with an oxidised low-density lipoprotein particle and delivering the oxidised low-density lipoprotein particle into the cell via endocytosis.	tmpzr1t_l9r_go_relaxed.owl	oxidised LDL particle receptor activity|ox-LDL receptor activity|oxidised low-density lipoprotein receptor activity|ox-LDL particle receptor activity|oxidized LDL particle receptor activity|oxidized LDL receptor activity|oxidised LDL receptor activity|oxidized low-density lipoprotein receptor activity|oxLDL particle receptor activity|oxidized low-density lipoprotein particle receptor activity|oxLDL receptor activity							bc	2018-02-06T14:17:33Z					molecular_function											owl:Class	
GO:0042134	biolink:NamedThing	rRNA primary transcript binding	Binding to an unprocessed ribosomal RNA transcript.	tmpzr1t_l9r_go_relaxed.owl	pre-rRNA binding													molecular_function											owl:Class	
GO:1901928	biolink:NamedThing	cadinene biosynthetic process	The chemical reactions and pathways resulting in the formation of cadinene.	tmpzr1t_l9r_go_relaxed.owl	cadinene synthesis|cadinene formation|cadinene biosynthesis|cadinene anabolism							ms	2013-02-18T14:54:34Z					biological_process											owl:Class	
GO:0061405	biolink:NamedThing	positive regulation of transcription from RNA polymerase II promoter in response to hydrostatic pressure	Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a hydrostatic pressure stimulus. Hydrostatic pressure is the force acting on an object in a system where the fluid is at rest (as opposed to moving). The weight of the fluid above the object creates pressure on it.	tmpzr1t_l9r_go_relaxed.owl								dph	2012-01-10T03:24:51Z					biological_process											owl:Class	
GO:0018513	biolink:NamedThing	dibenzothiophene dihydrodiol dehydrogenase activity	Catalysis of the reaction: cis-1,2-dihydroxy-1,2-dihydrodibenzothiophene + NAD(+) = 1,2-dihydroxydibenzothiophene + H(+) + NADH.	tmpzr1t_l9r_go_relaxed.owl	cis-1,2-dihydroxy-1,2-dihydrodibenzothiophene:NAD+ oxidoreductase activity				KEGG_REACTION:R05310|EC:1.3.1.60|MetaCyc:1.3.1.60-RXN|RHEA:24188|UM-BBD_reactionID:r0161									molecular_function											owl:Class	
GO:1901740	biolink:NamedThing	negative regulation of myoblast fusion	Any process that stops, prevents or reduces the frequency, rate or extent of myoblast fusion.	tmpzr1t_l9r_go_relaxed.owl	down regulation of myoblast fusion|down-regulation of myoblast fusion|downregulation of myoblast fusion|inhibition of myoblast fusion							rl	2013-01-11T20:23:55Z					biological_process											owl:Class	
GO:0019231	biolink:NamedThing	perception of static position	The perception of the orientation of different parts of the body with respect to one another.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0033432	biolink:NamedThing	CGG codon-amino acid adaptor activity	A triplet codon-amino acid adaptor activity that recognizes a CGG codon.	tmpzr1t_l9r_go_relaxed.owl	arginine tRNA					Note that in the standard genetic code, CGG codes for arginine.								molecular_function											owl:Class	
GO:0043804	biolink:NamedThing	imidazolone hydrolase activity	Catalysis of the reaction: N-formimidoylglycine => H2O + imidazol-4-one.	tmpzr1t_l9r_go_relaxed.owl					RHEA:24935	Note that this reaction can occur spontaneously (see RHEA:24937).								molecular_function											owl:Class	
GO:0018838	biolink:NamedThing	mandelate racemase activity	Catalysis of the reaction: (S)-mandelate = (R)-mandelate.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:MANDELATE-RACEMASE-RXN|RHEA:13945|EC:5.1.2.2|UM-BBD_reactionID:r0091									molecular_function											owl:Class	
GO:0045895	biolink:NamedThing	positive regulation of mating-type specific transcription, DNA-templated	Any mating-type specific process that activates or increases the rate of cellular DNA-templated transcription.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of mating-type specific transcription, DNA-dependent|up regulation of transcription, mating-type specific|up-regulation of transcription, mating-type specific|activation of transcription, mating-type specific|stimulation of transcription, mating-type specific|upregulation of transcription, mating-type specific													biological_process											owl:Class	
GO:0102996	biolink:NamedThing	beta,beta digalactosyldiacylglycerol galactosyltransferase activity	Catalysis of the reaction: a 1,2-diacyl-3-beta-D-galactosyl-sn-glycerol + a beta,beta digalactosyldiacylglycerol <=> a trigalactosyldiacylglycerol + a 1,2-diacyl-sn-glycerol.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-9721|EC:2.4.1.184									molecular_function											owl:Class	
GO:0075527	biolink:NamedThing	viral RNA editing	The process by which bases in viral mRNA are chemically altered during viral transcription. This is usually the incorporation of 1 - 6 additional nucleotides, which shifts the reading frame, allowing the generation of different protein products or through a specific nucleotide change that eliminates the termination codon.	tmpzr1t_l9r_go_relaxed.owl	RNA editing involved in viral mRNA transcription				VZ:857			jl	2011-08-04T02:07:03Z					biological_process											owl:Class	
GO:0046910	biolink:NamedThing	pectinesterase inhibitor activity	Binds to and stops, prevents or reduces the activity of pectinesterase.	tmpzr1t_l9r_go_relaxed.owl						See also the molecular function term 'pectinesterase activity ; GO:0030599'.								molecular_function											owl:Class	
GO:0050175	biolink:NamedThing	phenylalanine dehydrogenase activity	Catalysis of the reaction: L-phenylalanine + H2O + NAD+ = phenylpyruvate + NH3 + NADH.	tmpzr1t_l9r_go_relaxed.owl	L-phenylalanine dehydrogenase activity|PHD|L-phenylalanine:NAD+ oxidoreductase (deaminating)|PheDH activity				EC:1.4.1.20|MetaCyc:PHENYLALANINE-DEHYDROGENASE-RXN|RHEA:21408									molecular_function											owl:Class	
GO:0033487	biolink:NamedThing	pelargonidin 3-O-glucoside biosynthetic process	The chemical reactions and pathways resulting in the formation of pelargonidin 3-O-glucoside, a basic anthocyanin responsible for red to magenta coloration of flowers and fruits.	tmpzr1t_l9r_go_relaxed.owl	pelargonidin 3-O-glucoside anabolism|pelargonidin 3-O-glucoside biosynthesis|pelargonidin 3-O-glucoside formation|pelargonidin 3-O-glucoside synthesis				MetaCyc:PWY-5125									biological_process											owl:Class	
GO:0018782	biolink:NamedThing	cis-chloroacrylic acid dehalogenase activity	Catalysis of the reaction: cis-3-chloroacrylic acid + H2O = H+ + HCl + malonate semialdehyde.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0688									molecular_function											owl:Class	
GO:0051199	biolink:NamedThing	regulation of prosthetic group metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a prosthetic group.	tmpzr1t_l9r_go_relaxed.owl	regulation of coenzyme and prosthetic group metabolism|regulation of prosthetic group metabolism|regulation of coenzyme and prosthetic group metabolic process													biological_process											owl:Class	
GO:0098869	biolink:NamedThing	cellular oxidant detoxification	Any process carried out at the cellular level that reduces or removes the toxicity superoxide radicals or hydrogen peroxide.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0098669	biolink:NamedThing	superinfection exclusion	The process by which a preexisting viral infection prevents a secondary infection with the same or a closely related virus.  Typically some aspect of viral entry is inhibited, but post entry mechanisms have also been documented.	tmpzr1t_l9r_go_relaxed.owl					VZ:3971			dos	2017-01-16T17:25:21Z					biological_process											owl:Class	
GO:0106015	biolink:NamedThing	negative regulation of inflammatory response to wounding	Any process that stops, prevents, or reduces the frequency, rate or extent of the inflammatory response to wounding.	tmpzr1t_l9r_go_relaxed.owl								hjd	2017-04-28T20:09:46Z					biological_process											owl:Class	
GO:1990460	biolink:NamedThing	leptin receptor binding	Binding to a leptin receptor.	tmpzr1t_l9r_go_relaxed.owl								tb	2014-08-18T20:17:43Z					molecular_function											owl:Class	
GO:0003050	biolink:NamedThing	regulation of systemic arterial blood pressure by atrial natriuretic peptide	The regulation of blood pressure mediated by the signaling molecule atrial natriuretic peptide.	tmpzr1t_l9r_go_relaxed.owl	blood pressure regulation by atrial natriuretic peptide|blood pressure regulation by ANP													biological_process											owl:Class	
GO:0090163	biolink:NamedThing	establishment of epithelial cell planar polarity	The specification and formation of the polarity of an epithelial cell along the plane of the epithelial tissue.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-12-08T08:59:57Z					biological_process											owl:Class	
GO:0070905	biolink:NamedThing	serine binding	Binding to 2-amino-3-hydroxypropanoic acid.	tmpzr1t_l9r_go_relaxed.owl	Ser binding							mah	2009-09-04T03:28:29Z					molecular_function											owl:Class	
GO:0033889	biolink:NamedThing	N-sulfoglucosamine-3-sulfatase activity	Catalysis of the hydrolysis of the 3-sulfate groups of the N-sulfo-D-glucosamine 3-O-sulfate units of heparin.	tmpzr1t_l9r_go_relaxed.owl	chondroitinsulfatase activity|N-sulfo-3-sulfoglucosamine 3-sulfohydrolase activity				MetaCyc:3.1.6.15-RXN|EC:3.1.6.15									molecular_function											owl:Class	
GO:0036455	biolink:NamedThing	iron-sulfur transferase activity	Catalysis of the transfer of a iron-sulfur cluster from one compound (donor) to another (acceptor).	tmpzr1t_l9r_go_relaxed.owl	Fe-S transferase activity				Reactome:R-HSA-2564828			bf	2013-11-14T11:17:37Z					molecular_function											owl:Class	
GO:0102339	biolink:NamedThing	3-oxo-arachidoyl-CoA reductase activity	Catalysis of the reaction: (R)-3-hydroxyicosanoyl-CoA(4-) + NADP(3-) <=> 3-oxoicosanoyl-CoA + NADPH + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-13298|EC:1.1.1.330									molecular_function											owl:Class	
GO:0070075	biolink:NamedThing	tear secretion	The regulated release of the aqueous layer of the tear film from the lacrimal glands. Tears are the liquid product of a process of lacrimation to clean and lubricate the eyes. Tear fluid contains water, mucin, lipids, lysozyme, lactoferrin, lipocalin, lacritin, immunoglobulins, glucose, urea, sodium, and potassium.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0098872	biolink:NamedThing	G protein-coupled neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration	A G protein-coupled neurotransmitter receptor activity occurring in the postsynaptic membrane, that is involved in regulating the cytosolic concentration of calcium ions in the postsynapse.	tmpzr1t_l9r_go_relaxed.owl	G-protein coupled neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium levels|G-protein coupled neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration													molecular_function											owl:Class	
GO:0006060	biolink:NamedThing	sorbitol metabolic process	The chemical reactions and pathways involving sorbitol (D-glucitol), one of the ten stereoisomeric hexitols. It can be derived from glucose by reduction of the aldehyde group.	tmpzr1t_l9r_go_relaxed.owl	sorbitol metabolism				MetaCyc:P461-PWY									biological_process											owl:Class	
GO:0001081	biolink:NamedThing	nitrogen catabolite repression of transcription from RNA polymerase II promoter	A transcription regulation process in which the presence of one nitrogen source leads to a decrease in the frequency, rate, or extent of transcription, from an RNA polymerase II promoter, of specific genes involved in the metabolism of other nitrogen sources.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of transcription from RNA polymerase II promoter by nitrogen catabolites							krc	2010-10-27T03:38:05Z					biological_process											owl:Class	
GO:0015421	biolink:NamedThing	ABC-type oligopeptide transporter activity	Catalysis of the reaction: ATP + H2O + oligopeptide(out) = ADP + phosphate + oligopeptide(in).	tmpzr1t_l9r_go_relaxed.owl	ABC-type oligopeptide transporter|oligopeptide ABC transporter|ATP-dependent oligopeptide transmembrane transporter activity|oligopeptide permease activity|ATPase-coupled oligopeptide transmembrane transporter activity|oligopeptide-transporting ATPase activity				EC:7.4.2.6|RHEA:37271|Reactome:R-HSA-5223317|MetaCyc:3.6.3.23-RXN									molecular_function											owl:Class	
GO:0070230	biolink:NamedThing	positive regulation of lymphocyte apoptotic process	Any process that activates or increases the frequency, rate or extent of lymphocyte death by apoptotic process.	tmpzr1t_l9r_go_relaxed.owl	upregulation of lymphocyte apoptosis|positive regulation of lymphocyte apoptosis|stimulation of lymphocyte apoptosis|up regulation of lymphocyte apoptosis|up-regulation of lymphocyte apoptosis|activation of lymphocyte apoptosis					Note that a lymphocyte is a cell of the B cell, T cell, or natural killer cell lineage (CL:0000542).								biological_process											owl:Class	
GO:0050944	biolink:NamedThing	negative regulation of xanthophore differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of xanthophore differentiation.	tmpzr1t_l9r_go_relaxed.owl	downregulation of xanthophore differentiation|inhibition of xanthophore differentiation|down-regulation of xanthophore differentiation|down regulation of xanthophore differentiation					Note that this term refers to xanthophores in the sense of specialized pigment-producing cells, and should not be confused with the cellular component term 'xanthophore ; GO:0031633', which refers to a subcellular structure.								biological_process											owl:Class	
GO:0032686	biolink:NamedThing	negative regulation of hepatocyte growth factor production	Any process that stops, prevents, or reduces the frequency, rate, or extent of hepatocyte growth factor production.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of HGF production|negative regulation of scatter factor production|down regulation of hepatocyte growth factor production|negative regulation of hepatocyte growth factor biosynthetic process|inhibition of hepatocyte growth factor production|downregulation of hepatocyte growth factor production|down-regulation of hepatocyte growth factor production											GO:0048178		biological_process											owl:Class	
GO:0005131	biolink:NamedThing	growth hormone receptor binding	Binding to a growth hormone receptor.	tmpzr1t_l9r_go_relaxed.owl	growth hormone|growth hormone receptor ligand													molecular_function											owl:Class	
GO:0008782	biolink:NamedThing	adenosylhomocysteine nucleosidase activity	Catalysis of the reaction: S-adenosyl-L-homocysteine + H2O = adenine + S-D-ribosyl-L-homocysteine.	tmpzr1t_l9r_go_relaxed.owl	AdoHcy/MTA nucleosidase activity|S-adenosylhomocysteine/5'-methylthioadenosine nucleosidase activity|5'-methyladenosine nucleosidase activity|S-adenosyl-L-homocysteine homocysteinylribohydrolase activity|S-adenosylhomocysteine nucleosidase activity|S-adenosylhomocysteine hydrolase activity				MetaCyc:ADENOSYLHOMOCYSTEINE-NUCLEOSIDASE-RXN|EC:3.2.2.9|RHEA:17805									molecular_function											owl:Class	
GO:0009711	biolink:NamedThing	purine alkaloid biosynthetic process	The chemical reactions and pathways resulting in the breakdown of purine alkaloids, compounds derived from purine and composed of an N-containing double ring structure.	tmpzr1t_l9r_go_relaxed.owl	purine alkaloid anabolism|purine alkaloid synthesis|purine alkaloid biosynthesis|purine alkaloid formation													biological_process											owl:Class	
GO:0097624	biolink:NamedThing	UDP-galactose transmembrane import into Golgi lumen	The directed movement of UDP-galactose into the Golgi lumen across the Golgi membrane.	tmpzr1t_l9r_go_relaxed.owl	UDP-galactose import into Golgi lumen							pr	2014-08-18T14:59:23Z					biological_process											owl:Class	
GO:0036127	biolink:NamedThing	3-sulfino-L-alanine binding	Binding to 3-sulfino-L-alanine (cysteine sulfinate).	tmpzr1t_l9r_go_relaxed.owl	cysteine sulfinate binding							bf	2012-02-28T03:15:40Z					molecular_function											owl:Class	
GO:0048017	biolink:NamedThing	inositol lipid-mediated signaling	A series of molecular signals in which a cell uses an inositol-containing lipid to convert a signal into a response. Inositol lipids include the phosphoinositides (phosphatidylinositol and its phosphorylated derivatives), ceramides containing inositol, and inositol glycolipids.	tmpzr1t_l9r_go_relaxed.owl	inositol phospholipid-mediated signaling|inositol lipid-mediated signal transduction|inositol lipid-mediated signalling													biological_process											owl:Class	
GO:0016251	biolink:NamedThing	RNA polymerase II general transcription initiation factor activity	A general transcription initiation factor activity that contributes to transcription start site selection and transcription initiation of genes transcribed by RNA polymerase II. The general transcription factors for RNA polymerase II include TFIIB, TFIID, TFIIE, TFIIF, TFIIH and TATA-binding protein (TBP). In most species, RNA polymerase II transcribes all messenger RNAs (mRNAs), most untranslated regulatory RNAs, the majority of the snoRNAs, four of the five snRNAs (U1, U2, U4, and U5), and other small noncoding RNAs. For some small RNAs there is variability between species as to whether it is transcribed by RNA polymerase II or RNA polymerase III. However there are also rare exceptions, such as Trypanosoma brucei, where RNA polymerase I transcribes certain mRNAs in addition to its normal role in rRNA transcription.	tmpzr1t_l9r_go_relaxed.owl	RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity|transcription factor activity, RNA polymerase II core promoter sequence-specific DNA binding|RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity involved in preinitiation complex assembly|sequence-specific core promoter binding RNA polymerase II transcription factor activity involved in preinitiation complex assembly|general RNA polymerase II transcription factor activity|GTF2 activity|transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly|basal RNA polymerase II transcription factor activity	https://github.com/geneontology/go-ontology/issues/20253				General transcription factors assemble with the RNA polymerase at promoter DNA to form the pre-initiation complex (PIC), bind to and open promoter DNA, initiate RNA synthesis and stimulate the escape of the polymerase from the promoter. Not all subunits of the general transcription factor are necessarily present in all promoters to initiate transcription. The distinction between general transcription factors and DNA-binding transcription factors is that the latter modulate the selection of which genes are expressed under specific conditions, while general transcription factors belong to the constitutive machinery required for transcription to occur.						GO:0001075|GO:0000983|GO:0003703		molecular_function											owl:Class	
GO:0050590	biolink:NamedThing	desacetoxyvindoline 4-hydroxylase activity	Catalysis of the reaction: desacetoxyvindoline + 2-oxoglutarate + O2 = desacetylvindoline + succinate + CO2.	tmpzr1t_l9r_go_relaxed.owl	desacetoxyvindoline,2-oxoglutarate:oxygen oxidoreductase (4beta-hydroxylating)|desacetoxyvindoline,2-oxoglutarate:oxygen oxidoreductase (4-beta-hydroxylating) activity|desacetoxyvindoline-4-hydroxylase activity|D17H activity|deacetoxyvindoline,2-oxoglutarate:oxygen oxidoreductase (4beta-hydroxylating)|desacetyoxyvindoline-17-hydroxylase activity				KEGG_REACTION:R05857|MetaCyc:1.14.11.20-RXN|RHEA:18973|EC:1.14.11.20									molecular_function											owl:Class	
GO:0042017	biolink:NamedThing	interleukin-22 binding	Binding to interleukin-22.	tmpzr1t_l9r_go_relaxed.owl	IL-22 binding													molecular_function											owl:Class	
GO:0061880	biolink:NamedThing	regulation of anterograde axonal transport of mitochondrion	Any process that modulates the frequency, rate or extent of the directed movement of mitochondria along microtubules in axons away from the cell body and towards the presynapse.	tmpzr1t_l9r_go_relaxed.owl	regulation of anterograde axon transport of mitochondria							dph	2017-05-30T14:15:46Z					biological_process											owl:Class	
GO:1903135	biolink:NamedThing	cupric ion binding	Binding to a cupric ion, copper(2+).	tmpzr1t_l9r_go_relaxed.owl	Cu(II) binding|copper(2+)binding|Cu(2+) binding							bf	2014-06-26T14:38:16Z					molecular_function											owl:Class	
GO:0008833	biolink:NamedThing	deoxyribonuclease IV (phage-T4-induced) activity	Catalysis of the endonucleolytic cleavage to 5'-phosphooligonucleotide end-products.	tmpzr1t_l9r_go_relaxed.owl	E. coli endonuclease IV|DNA-adenine-transferase activity|endonuclease II|endonuclease IV activity|endodeoxyribonuclease IV (phage T4-induced) activity|Escherichia coli endonuclease II|endodeoxyribonuclease IV (phage T(4)-induced) activity|redoxyendonuclease activity|deoxriboendonuclease activity|deoxyribonuclease IV (phage T4-induced) activity				EC:3.1.21.2|MetaCyc:3.1.21.2-RXN									molecular_function											owl:Class	
GO:0015092	biolink:NamedThing	high-affinity ferric iron transmembrane transporter activity	Enables the transfer of ferric iron (Fe(III) or Fe3+) ions from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.	tmpzr1t_l9r_go_relaxed.owl	high affinity ferric uptake transmembrane transporter activity	https://github.com/geneontology/go-ontology/issues/14372												molecular_function											owl:Class	
GO:1903876	biolink:NamedThing	11-deoxycortisol binding	Binding to 11-deoxycortisol.	tmpzr1t_l9r_go_relaxed.owl								mr	2015-02-06T16:02:44Z					molecular_function											owl:Class	
GO:0034321	biolink:NamedThing	alcohol O-octanoyltransferase activity	Catalysis of the reaction: octanoyl-CoA + an alcohol = CoA + an octyl ester.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0071748	biolink:NamedThing	monomeric IgA immunoglobulin complex	A protein complex composed of two identical immunoglobulin heavy chains of an IgA isotype and two identical immunoglobulin light chains, held together by disulfide bonds, and present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.	tmpzr1t_l9r_go_relaxed.owl	monomeric IgA1 antibody|monomeric IgA antibody|monomeric IgA2 antibody					Note that an IgA immunoglobulin complex has the function of antigen binding if a suitable antigen is available.		mah	2010-03-24T01:44:53Z					cellular_component											owl:Class	
GO:0034717	biolink:NamedThing	Gemin6-Gemin7-unrip complex	A protein complex that contains Gemin6, Gemin7, and unrip (STRAP), and can bind to snRNAs; may play a role in snRNP assembly.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0070928	biolink:NamedThing	regulation of mRNA stability, ncRNA-mediated	Any process, mediated by small non-coding RNAs, that modulates the propensity of mRNA molecules to degradation. Includes processes that both stabilize and destabilize mRNAs.	tmpzr1t_l9r_go_relaxed.owl	regulation of mRNA stability, non-coding RNA-mediated|ncRNA-mediated regulation of mRNA stability							mah	2009-09-16T03:26:21Z					biological_process											owl:Class	
GO:0061675	biolink:NamedThing	RBL family protein binding	Binding to a member of the rhamnose-binding lectin (RBL) family, a family of animal lectins that show specific binding activities to L-rhamnose or D-galactose.	tmpzr1t_l9r_go_relaxed.owl	rhamnose-binding lectin family protein binding							dph	2015-01-10T18:22:42Z					molecular_function											owl:Class	
GO:0036370	biolink:NamedThing	D-alanyl carrier activity	Binding a D-alanine and presenting it for processing or offloading to a cognate enzyme. Covalently binds the D-alanine via a phosphopantetheine prosthetic group and mediates protein-protein interactions with the enzyme conferring specificity. The carrier protein provides an essential link between the D-alanine-D-alanyl carrier protein ligase and the incorporation of D-alanine into lipoteichoic acid by transferring activated D-alanine to cell membrane phosphatidylglycerol (PG).	tmpzr1t_l9r_go_relaxed.owl	D-alanyl carrier protein							bf	2012-10-08T10:30:33Z					molecular_function											owl:Class	
GO:0009671	biolink:NamedThing	nitrate:proton symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: nitrate(out) + H+(out) = nitrate(in) + H+(in).	tmpzr1t_l9r_go_relaxed.owl	nitrate:hydrogen symporter activity|nitrate(chlorate):hydrogen symporter activity|nitrate(chlorate):proton symporter activity													molecular_function											owl:Class	
GO:0018801	biolink:NamedThing	glutaconyl-CoA decarboxylase activity	Catalysis of the reaction: trans-glutaconyl-CoA + H(+) = but-2-enoyl-CoA + CO(2).	tmpzr1t_l9r_go_relaxed.owl	pent-2-enoyl-CoA carboxy-lyase activity|4-carboxybut-2-enoyl-CoA carboxy-lyase activity|4-carboxybut-2-enoyl-CoA carboxy-lyase (but-2-enoyl-CoA-forming)|glutaconyl coenzyme A decarboxylase activity				EC:7.2.4.5|MetaCyc:GLUTACONYL-COA-DECARBOXYLASE-RXN|UM-BBD_reactionID:r0199|RHEA:23972|KEGG_REACTION:R03028									molecular_function											owl:Class	
GO:0070885	biolink:NamedThing	negative regulation of calcineurin-NFAT signaling cascade	Any process that stops, prevents, or reduces the frequency, rate or extent of the calcineurin-NFAT signaling cascade.	tmpzr1t_l9r_go_relaxed.owl	inhibition of NFAT protein import into nucleus|negative regulation of NFAT protein import into nucleus|down-regulation of calcineurin-NFAT signaling cascade|negative regulation of calcineurin-NFAT signaling pathway|termination of calcineurin-NFAT signaling cascade|inhibition of calcineurin-NFAT signaling cascade|downregulation of calcineurin-NFAT signaling cascade|down regulation of calcineurin-NFAT signaling cascade|negative regulation of calcineurin-NFAT signalling cascade							mah	2009-08-26T03:29:33Z			GO:0051534		biological_process											owl:Class	
GO:0004732	biolink:NamedThing	pyridoxal oxidase activity	Catalysis of the reaction: pyridoxal + H2O + O2 = 4-pyridoxate + hydrogen peroxide.	tmpzr1t_l9r_go_relaxed.owl	pyridoxal:oxygen 4-oxidoreductase activity				MetaCyc:PYRIDOXAL-OXIDASE-RXN|EC:1.2.3.8|RHEA:23724									molecular_function											owl:Class	
GO:0005159	biolink:NamedThing	insulin-like growth factor receptor binding	Binding to an insulin-like growth factor receptor.	tmpzr1t_l9r_go_relaxed.owl	insulin-like growth factor receptor ligand|insulin-like growth factor|IGF receptor binding											GO:0005067		molecular_function											owl:Class	
GO:2000638	biolink:NamedThing	regulation of SREBP signaling pathway	Any process that modulates the frequency, rate or extent of the SREBP signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	regulation of SREBP-mediated signaling pathway|regulation of SREBP-mediated signalling pathway							vk	2011-04-20T02:45:59Z					biological_process											owl:Class	
GO:0015840	biolink:NamedThing	urea transport	The directed movement of urea into, out of or within the cell. Urea is the water-soluble compound H2N-CO-NH2.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0046052	biolink:NamedThing	UTP catabolic process	The chemical reactions and pathways resulting in the breakdown of UTP, uridine (5'-)triphosphate.	tmpzr1t_l9r_go_relaxed.owl	UTP catabolism|UTP degradation|UTP hydrolysis|UTP breakdown													biological_process											owl:Class	
GO:0102250	biolink:NamedThing	linear malto-oligosaccharide phosphorylase activity	Catalysis of the reaction: hydrogenphosphate + a linear malto-oligosaccharide = alpha-D-glucose 1-phosphate + a linear malto-oligosaccharide.	tmpzr1t_l9r_go_relaxed.owl					EC:2.4.1.1|MetaCyc:RXN-12392									molecular_function											owl:Class	
GO:0085034	biolink:NamedThing	suppression by symbiont of host I-kappaB kinase/NF-kappaB cascade	Any process that stops, prevents, or reduces the frequency, rate or extent of host NF-kappaB-mediated signal transduction pathways during the host defense response. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	negative regulation by symbiont of host I-kappaB kinase/NF-kappaB cascade							jl	2010-07-27T03:32:44Z					biological_process											owl:Class	
GO:0045509	biolink:NamedThing	interleukin-27 receptor activity	Combining with interleukin-27 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	IL-27 receptor activity|IL-27R													molecular_function											owl:Class	
GO:1904681	biolink:NamedThing	response to 3-methylcholanthrene	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 3-methylcholanthrene stimulus.	tmpzr1t_l9r_go_relaxed.owl								mr	2015-09-22T19:50:03Z					biological_process											owl:Class	
GO:0005461	biolink:NamedThing	UDP-glucuronic acid transmembrane transporter activity	Enables the transfer of a UDP-glucuronic acid from one side of a membrane to the other. UDP-glucuronic acid is a substance composed of glucuronic acid in glycosidic linkage with uridine diphosphate.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-5603297|Reactome:R-HSA-174368									molecular_function											owl:Class	
GO:0046452	biolink:NamedThing	dihydrofolate metabolic process	The chemical reactions and pathways involving dihydrofolate, the dihydroxylated derivative of folate.	tmpzr1t_l9r_go_relaxed.owl	dihydrofolate metabolism|dihydrofolate reduction													biological_process											owl:Class	
GO:0071364	biolink:NamedThing	cellular response to epidermal growth factor stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an epidermal growth factor stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to EGF stimulus							mah	2009-12-11T03:05:34Z					biological_process											owl:Class	
GO:1903101	biolink:NamedThing	1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate catabolic process	The chemical reactions and pathways resulting in the breakdown of 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate.	tmpzr1t_l9r_go_relaxed.owl	1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate degradation|1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate breakdown|1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate catabolism							bhm	2014-06-04T14:14:30Z					biological_process											owl:Class	
GO:0052856	biolink:NamedThing	NADHX epimerase activity	Catalysis of the reaction: (R)-NADHX = (S)-NADHX.	tmpzr1t_l9r_go_relaxed.owl					RHEA:32215|EC:5.1.99.6									molecular_function											owl:Class	
GO:0039719	biolink:NamedThing	tube viral factory	A cytoplasmic viral factory derived from the Golgi in which Bunyaviridae replication takes place. Tubes are membranous structures close to the assembly and budding sites, and their function may be to connect viral replication and morphogenesis inside viral factories.	tmpzr1t_l9r_go_relaxed.owl								bf	2013-12-19T15:34:56Z					cellular_component											owl:Class	
GO:0004173	biolink:NamedThing	ecdysone O-acyltransferase activity	Catalysis of the reaction: Ecdysone + palmitoyl-CoA = CoA + ecdysone palmitate.	tmpzr1t_l9r_go_relaxed.owl	fatty acyl-CoA:ecdysone acyltransferase activity|acyl-CoA:ecdysone acyltransferase activity|palmitoyl-CoA:ecdysone palmitoyltransferase activity				MetaCyc:ECDYSONE-O-ACYLTRANSFERASE-RXN|KEGG_REACTION:R02375|EC:2.3.1.139|RHEA:15217									molecular_function											owl:Class	
GO:0044585	biolink:NamedThing	cellobiose binding	Binding to cellobiose, a disaccharide that represents the basic repeating unit of cellulose.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-04-24T04:55:10Z					molecular_function											owl:Class	
GO:0021746	biolink:NamedThing	solitary nucleus development	The process whose specific outcome is the progression of the solitary nucleus over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0090345	biolink:NamedThing	cellular organohalogen metabolic process	The chemical reactions and pathways involving organohalogen compounds, as carried out by individual cells.	tmpzr1t_l9r_go_relaxed.owl								tb	2010-06-02T10:36:42Z					biological_process											owl:Class	
GO:1901002	biolink:NamedThing	positive regulation of response to salt stress	Any process that activates or increases the frequency, rate or extent of response to salt stress.	tmpzr1t_l9r_go_relaxed.owl	upregulation of response to ionic osmotic stress|up-regulation of response to ionic osmotic stress|positive regulation of response to ionic osmotic stress|activation of response to salt stress|activation of response to ionic osmotic stress|up-regulation of response to salt stress|up regulation of response to ionic osmotic stress|up regulation of response to salt stress|upregulation of response to salt stress|upregulation of salinity response|positive regulation of salinity response|activation of salinity response|up regulation of salinity response|up-regulation of salinity response							dhl	2012-06-14T05:41:50Z					biological_process											owl:Class	
GO:0140067	biolink:NamedThing	peptidyl-lysine butyrylation	The butyrylation of a lysine residue in a protein. Butyryl is the univalent radical C3H7COO- derived from butyric acid.	tmpzr1t_l9r_go_relaxed.owl								pg	2017-07-20T16:52:19Z					biological_process											owl:Class	
GO:0002056	biolink:NamedThing	cytosine binding	Binding to cytosine.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0021518	biolink:NamedThing	spinal cord commissural neuron specification	The process in which a cell becomes capable of differentiating autonomously into a commissural neuron in an environment that is neutral with respect to the developmental pathway.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0102084	biolink:NamedThing	L-dopa O-methyltransferase activity	Catalysis of the reaction: L-dopa + S-adenosyl-L-methionine  <=> 3-O-methyldopa + S-adenosyl-L-homocysteine + H+.	tmpzr1t_l9r_go_relaxed.owl					EC:2.1.1.6|MetaCyc:RXN-10870									molecular_function											owl:Class	
GO:0030466	biolink:NamedThing	silent mating-type cassette heterochromatin assembly	Repression of transcription at silent mating-type loci by alteration of the structure of chromatin.	tmpzr1t_l9r_go_relaxed.owl	chromatin silencing at silent mating-type cassette|heterochromatic silencing at silent mating-type cassette|silent mating-type cassette chromatin silencing|aging-dependent sterility|establishment of chromatin silencing at silent mating-type cassette|chromatin silencing at HML and HMR	https://github.com/geneontology/go-ontology/issues/19112										GO:0035389|GO:0006347		biological_process											owl:Class	
GO:0103031	biolink:NamedThing	L-Ala-D/L-Glu epimerase activity	Catalysis of the reaction: L-alanyl-D-glutamate = L-alanyl-L-glutamate.	tmpzr1t_l9r_go_relaxed.owl					RHEA:28394|MetaCyc:RXN0-5228									molecular_function											owl:Class	
GO:0120298	biolink:NamedThing	peptide noradrenalinyltransferase activity	Catalysis of the reaction: (R)-noradrenaline + L-glutaminyl-[protein] = 5-(R)-noradrenalinyl-L-glutamyl-[protein] + NH4(+).	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/20685			RHEA:66560			krc	2021-01-19T03:20:26Z					molecular_function											owl:Class	
GO:0070210	biolink:NamedThing	Rpd3L-Expanded complex	A protein complex that contains a histone deacetylase and is part of the chromatin remodeling machinery. In Saccharomyces cerevisiae this complex contains the Rpd3p, Sin3p, Ume1p, Pho23p, Sap30p, Sds3p, Cti6p, Rxt2p, Rxt3p, Dep1p, Ume6p, Ash1p, Dot6p, Snt1, Sif2p, Set3p, Hos2p, Tos4p and Tod6p proteins.	tmpzr1t_l9r_go_relaxed.owl	Clr6-LE complex													cellular_component											owl:Class	
GO:2000086	biolink:NamedThing	positive regulation of mesenchymal to epithelial transition involved in mesonephros morphogenesis	Any process that activates or increases the frequency, rate or extent of mesenchymal to epithelial transition involved in mesonephros morphogenesis.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of mesonephric mesenchyme to epithelial transition							dph	2010-09-03T06:08:24Z					biological_process											owl:Class	
GO:0071493	biolink:NamedThing	cellular response to UV-B	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-B radiation stimulus. UV-B radiation (UV-B light) spans the wavelengths 280 to 315 nm.	tmpzr1t_l9r_go_relaxed.owl	cellular response to UV-B light stimulus|cellular response to UVB radiation stimulus|cellular response to UVB light stimulus|cellular response to medium wave ultraviolet light stimulus|cellular response to UV-B radiation stimulus|cellular response to medium wave ultraviolet radiation stimulus							mah	2009-12-18T02:21:56Z					biological_process											owl:Class	
GO:0010224	biolink:NamedThing	response to UV-B	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-B radiation stimulus. UV-B radiation (UV-B light) spans the wavelengths 280 to 315 nm.	tmpzr1t_l9r_go_relaxed.owl	response to medium wave ultraviolet radiation stimulus|response to UVB light stimulus|response to medium wave ultraviolet light stimulus|response to UVB radiation stimulus|response to UV-B light stimulus|response to UV-B radiation stimulus													biological_process											owl:Class	
GO:1902197	biolink:NamedThing	isovaleryl-CoA(4-) biosynthetic process	The chemical reactions and pathways resulting in the formation of isovaleryl-CoA(4-).	tmpzr1t_l9r_go_relaxed.owl	isovaleryl-CoA(4-) synthesis|isovaleryl-CoA(4-) biosynthesis|isovaleryl-CoA(4-) anabolism|isovaleryl-CoA(4-) formation							ms	2013-06-06T09:56:05Z					biological_process											owl:Class	
GO:0060659	biolink:NamedThing	nipple sheath formation	The developmental process pertaining to the initial formation of the nipple sheath from the unspecified epidermis. This process begins with a circular ingrowth of the epidermis around the region of the mammary sprout. It ends before the region begins to elevate.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-05-29T10:48:39Z					biological_process											owl:Class	
GO:0070309	biolink:NamedThing	lens fiber cell morphogenesis	The process in which the structures of a lens fiber cell are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a lens fiber cell. A lens fiber cell is any of the elongated, tightly packed cells that make up the bulk of the mature lens in a camera-type eye.	tmpzr1t_l9r_go_relaxed.owl	lens fiber cell morphogenesis during differentiation|elongation of lens fiber cell|lens fibre cell morphogenesis													biological_process											owl:Class	
GO:0060141	biolink:NamedThing	positive regulation of syncytium formation by virus	The process in which a virus increases the frequency, rate or extent of the formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells.	tmpzr1t_l9r_go_relaxed.owl	syncytium formation induced by viral infection													biological_process											owl:Class	
GO:0005298	biolink:NamedThing	proline:sodium symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: proline(out) + Na+(out) = proline(in) + Na+(in).	tmpzr1t_l9r_go_relaxed.owl	sodium/proline symporter activity				Reactome:R-HSA-444100|RHEA:28967									molecular_function											owl:Class	
GO:0097335	biolink:NamedThing	response to quetiapine	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a quetiapine stimulus.	tmpzr1t_l9r_go_relaxed.owl								pr	2012-06-12T11:03:22Z					biological_process											owl:Class	
GO:0032729	biolink:NamedThing	positive regulation of interferon-gamma production	Any process that activates or increases the frequency, rate, or extent of interferon-gamma production. Interferon-gamma is also known as type II interferon.	tmpzr1t_l9r_go_relaxed.owl	upregulation of interferon-gamma production|activation of interferon-gamma production|stimulation of interferon-gamma production|up regulation of interferon-gamma production|positive regulation of interferon-gamma biosynthetic process|up-regulation of interferon-gamma production|positive regulation of interferon-gamma secretion|positive regulation of type II interferon production											GO:0045078|GO:1902715		biological_process											owl:Class	
GO:0090159	biolink:NamedThing	sphingolipid biosynthesis involved in endoplasmic reticulum membrane organization	The chemical reactions and pathways resulting in the formation of sphingolipids that contributes to endoplasmic reticulum membrane organization.	tmpzr1t_l9r_go_relaxed.owl	sphingolipid biosynthesis involved in endoplasmic reticulum membrane organisation							tb	2009-12-08T08:31:13Z					biological_process											owl:Class	
GO:0004936	biolink:NamedThing	alpha-adrenergic receptor activity	Combining with epinephrine or norepinephrine to initiate a change in cell activity via activation of a G protein, with pharmacological characteristics of alpha-adrenergic receptors.	tmpzr1t_l9r_go_relaxed.owl	alpha adrenoceptor													molecular_function											owl:Class	
GO:0043820	biolink:NamedThing	propionyl-CoA dehydrogenase activity	Catalysis of the irreversible NADH-dependent formation of propionyl-CoA from acryloyl-CoA.	tmpzr1t_l9r_go_relaxed.owl					EC:1.3.99.-									molecular_function											owl:Class	
GO:0097520	biolink:NamedThing	nucleotide-excision repair, preincision complex	A multiprotein complex involved in damage recognition, DNA helix unwinding, and endonucleolytic cleavage at the site of DNA damage.	tmpzr1t_l9r_go_relaxed.owl	UvrB dimer|UvrA(2)-UvrB(2) complex|UvrA(2)B(2) complex							pr	2013-10-17T14:32:37Z					cellular_component											owl:Class	
GO:0051700	biolink:NamedThing	fructosyl-amino acid oxidase activity	Catalysis of the reaction: fructosyl-amino acid + O2 = corresponding amino acid + glucosone + H2O2.	tmpzr1t_l9r_go_relaxed.owl	FAOD activity													molecular_function											owl:Class	
GO:0007490	biolink:NamedThing	tergite morphogenesis	The process in which the anatomical structures of the tergite are generated and organized. The tergite is the primary plate or sclerite forming the dorsal surface of any insect body segment.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0090444	biolink:NamedThing	regulation of nematode larval development, heterochronic	Any process that modulates the consistent predetermined time point at which a nematode larva progresses from an initial condition to a later condition and the rate at which this time point is reached.	tmpzr1t_l9r_go_relaxed.owl								tb	2012-08-24T13:24:43Z					biological_process											owl:Class	
GO:0140348	biolink:NamedThing	lysophosphatidylcholine flippase activity	Catalysis of the movement of lysophosphatidylcholine from the exoplasmic to the cytosolic leaftlet of a membrane, using energy from the hydrolysis of ATP.	tmpzr1t_l9r_go_relaxed.owl	lysophosphatidylcholine flippase activity (exoplasmic to cytosolic leaftlet)							pg	2019-05-16T13:45:17Z					molecular_function											owl:Class	
GO:0022894	biolink:NamedThing	Intermediate conductance calcium-activated potassium channel activity	Enables the transmembrane transfer of potassium by a channel with a unit conductance of 20 to 85 picoSiemens that opens in response to stimulus by internal calcium ions. Intermediate conductance calcium-activated potassium channels are more sensitive to calcium than are large conductance calcium-activated potassium channels. Transport by a channel involves catalysis of facilitated diffusion of a solute (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel, without evidence for a carrier-mediated mechanism.	tmpzr1t_l9r_go_relaxed.owl	IK KCa channels|intermdiate conductance KCa channels|IK calcium-activated potassium channel activity													molecular_function											owl:Class	
GO:0043658	biolink:NamedThing	host symbiosome	A double-enveloped cell compartment, composed of the endosymbiont with its plasmalemma (as inner envelope) and an outer envelope (the perisymbiontic membrane) derived from the host cell.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0140455	biolink:NamedThing	cytoplasm protein quality control	The chemical reactions and pathways resulting in the breakdown of misfolded proteins in the cytoplasm, which are either targeted to cytoplasmic proteasomes for degradation or protected by chaperones to shield thermosensitive proteins from degradation until conditions allow disaggregation and refolding.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/19172						pg	2020-04-20T15:46:20Z					biological_process											owl:Class	
GO:0042838	biolink:NamedThing	D-glucarate catabolic process	The chemical reactions and pathways resulting in the breakdown of D-glucarate, the D-enantiomer of glucarate.	tmpzr1t_l9r_go_relaxed.owl	D-glucarate breakdown|D-glucarate catabolism|D-glucarate degradation|saccharate catabolic process|saccharate catabolism													biological_process											owl:Class	
GO:0046575	biolink:NamedThing	rhamnogalacturonan acetylesterase activity	Catalysis of the removal of acetylesters (as acetate) from galacturonic acid residues in the backbone of rhamnogalacturonan.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0071261	biolink:NamedThing	Ssh1 translocon complex	A translocon complex that contains a core heterotrimer of alpha, beta and gamma subunits, and may contain additional proteins (translocon-associated proteins or TRAPs); in budding yeast the core proteins are Ssh1p, Sbh2p, and Sss1p. The Ssh1 translocon complex is involved in the cotranslational pathway of protein transport across the ER membrane, and recognizes proteins bearing strongly hydrophobic signal sequences.	tmpzr1t_l9r_go_relaxed.owl	Ssh1p-Sss1p-Sbh2p complex							mah	2009-12-08T02:22:55Z					cellular_component											owl:Class	
GO:0020030	biolink:NamedThing	infected host cell surface knob	Protrusion that develops in the plasma membrane of a parasitized erythrocyte. An example of this component is found in Plasmodium species.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0052842	biolink:NamedThing	inositol diphosphate pentakisphosphate diphosphatase activity	Catalysis of the reaction: inositol diphosphate pentakisphosphate + H2O = inositol hexakisphosphate + phosphate.	tmpzr1t_l9r_go_relaxed.owl					KEGG_REACTION:R05779|Reactome:R-HSA-1855198|RHEA:22384|Reactome:R-HSA-2023971|EC:3.6.1.52			ai	2011-11-29T04:14:22Z					molecular_function											owl:Class	
GO:0030346	biolink:NamedThing	protein phosphatase 2B binding	Binding to a protein phosphatase 2B.	tmpzr1t_l9r_go_relaxed.owl	calcineurin binding|protein phosphatase 3 binding													molecular_function											owl:Class	
GO:0018044	biolink:NamedThing	C-terminal peptidyl-leucine amidation	The formation of a C-terminal peptidyl-leucine amide by hydrolysis and oxidation of an interior Leu-Gly peptide in a secreted protein.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0091									biological_process											owl:Class	
GO:0061649	biolink:NamedThing	ubiquitin modification-dependent histone binding	Binding to a histone protein in which a residue has been modified by ubiquitination. Histones are any of a group of water-soluble proteins found in association with the DNA of eukaroytic chromosomes.	tmpzr1t_l9r_go_relaxed.owl	ubiquitinated histone binding							dph	2014-11-04T10:21:04Z					molecular_function											owl:Class	
GO:0140036	biolink:NamedThing	ubiquitin-dependent protein binding	Binding to a protein upon ubiquitination of the target protein.	tmpzr1t_l9r_go_relaxed.owl						This term should only be used when the binding is shown to require ubiquitination of the target protein: the interaction needs to be tested with and without the PTM. The binding does not need to be at the site of ubiquitination. It may be that the ubiquitination causes a conformational change that allows binding of the protein to another region; this type of ubiquitination-dependent protein binding is valid for annotation to this term.		pg	2017-05-18T06:29:14Z					molecular_function											owl:Class	
GO:0071846	biolink:NamedThing	actin filament debranching	An actin filament severing process that results in the removal of actin filament branches specifically at the branch points.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-09-10T02:15:42Z					biological_process											owl:Class	
GO:0050141	biolink:NamedThing	nitroethane oxidase activity	Catalysis of the reaction: nitroethane + H2O + O2 = acetaldehyde + nitrite + H2O2.	tmpzr1t_l9r_go_relaxed.owl	nitroethane:oxygen oxidoreductase activity|nitroethane reductase activity				MetaCyc:NITROETHANE-OXIDASE-RXN|EC:1.7.3.1									molecular_function											owl:Class	
GO:0052664	biolink:NamedThing	nitroalkane oxidase activity	Catalysis of the reaction: nitroalkane + H2O + O2 = an aldehyde or ketone + nitrite + H2O2.	tmpzr1t_l9r_go_relaxed.owl	NAO activity|nitroalkane:oxygen oxidoreductase activity|nitroalkane reductase activity				MetaCyc:RXN-11045|EC:1.7.3.1|KEGG_REACTION:R00799				2010-10-11T10:50:59Z					molecular_function											owl:Class	
GO:0001967	biolink:NamedThing	suckling behavior	Specific behavior of a newborn or infant mammal that results in the derivation of nourishment from the breast.	tmpzr1t_l9r_go_relaxed.owl	nursing behavior													biological_process											owl:Class	
GO:0070369	biolink:NamedThing	beta-catenin-TCF7L2 complex	A protein complex that contains beta-catenin and TCF7L2 (TCF4), binds to the TCF DNA motif within a promoter element, and is involved in the regulation of WNT target gene transcription.	tmpzr1t_l9r_go_relaxed.owl	beta-catenin-TCF4 complex													cellular_component											owl:Class	
GO:1990907	biolink:NamedThing	beta-catenin-TCF complex	A protein complex that contains beta-catenin and a member of the T-cell factor (TCF)/lymphoid enhancer binding factor (LEF) family of transcription factors.	tmpzr1t_l9r_go_relaxed.owl	beta-catenin/LEF complex|beta-catenin/lymphoid enhancer binding factor complex|beta-catenin/T-cell factor complex							bf	2015-12-01T16:32:44Z					cellular_component											owl:Class	
GO:0042190	biolink:NamedThing	vanillin catabolic process	The chemical reactions and pathways resulting in the breakdown of vanillin, an aromatic hydrocarbon which occurs naturally in black vanilla bean pods.	tmpzr1t_l9r_go_relaxed.owl	vanillin degradation|vanillin breakdown|vanillin catabolism|vanillic aldehyde catabolic process|vanillic aldehyde catabolism													biological_process											owl:Class	
GO:0016287	biolink:NamedThing	glycerone-phosphate O-acyltransferase activity	Catalysis of the reaction: acyl-CoA + glycerone phosphate = 1-acylglycerone 3-phosphate + CoA.	tmpzr1t_l9r_go_relaxed.owl	dihydroxyacetone phosphate acyltransferase activity|acyl-CoA:glycerone-phosphate O-acyltransferase activity				RHEA:17657|EC:2.3.1.42|MetaCyc:2.3.1.42-RXN|Reactome:R-HSA-75879|KEGG_REACTION:R01013|Reactome:R-HSA-1483002									molecular_function											owl:Class	
GO:0106176	biolink:NamedThing	clathrin-coated endocytic vesicle lumen	The volume enclosed by the membrane of a clathrin-coated endocytic vesicle.	tmpzr1t_l9r_go_relaxed.owl								hjd	2019-02-12T15:44:51Z					cellular_component											owl:Class	
GO:0004534	biolink:NamedThing	5'-3' exoribonuclease activity	Catalysis of the sequential cleavage of mononucleotides from a free 5' terminus of an RNA molecule.	tmpzr1t_l9r_go_relaxed.owl					EC:3.1.13.-|Reactome:R-HSA-429845									molecular_function											owl:Class	
GO:0097203	biolink:NamedThing	phagocytic cup lip	The tip or margin of the progressing circular lamella that engulfs a particle during phagocytosis. When the two lips of the cup fuse it is converted into a phagosome.	tmpzr1t_l9r_go_relaxed.owl								pr	2011-12-21T10:26:41Z					cellular_component											owl:Class	
GO:0090392	biolink:NamedThing	sepal giant cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a sepal giant cell. A sepal giant cell is a pavement cell that is part of the sepal epidermis and stretches one fifth the length of the sepal with a chromosome content of 16C.	tmpzr1t_l9r_go_relaxed.owl								tb	2010-12-14T04:38:06Z					biological_process											owl:Class	
GO:1903265	biolink:NamedThing	positive regulation of tumor necrosis factor-mediated signaling pathway	Any process that activates or increases the frequency, rate or extent of tumor necrosis factor-mediated signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of adipocytokine signaling pathway|upregulation of tumor necrosis factor alpha-mediated signaling pathway|upregulation of adipocytokine signaling pathway|up regulation of tumor necrosis factor-mediated signaling pathway|positive regulation of TNF-alpha-mediated signaling pathway|activation of tumor necrosis factor alpha-mediated signaling pathway|up regulation of adipocytokine signaling pathway|activation of adipocytokine signaling pathway|positive regulation of tumor necrosis factor-mediated signalling pathway|positive regulation of tumor necrosis factor alpha-mediated signaling pathway|up-regulation of tumor necrosis factor-mediated signaling pathway|up-regulation of TNF-alpha-mediated signaling pathway|upregulation of tumor necrosis factor-mediated signalling pathway|up-regulation of tumor necrosis factor-mediated signalling pathway|activation of TNF-alpha-mediated signaling pathway|activation of tumor necrosis factor-mediated signaling pathway|activation of tumor necrosis factor-mediated signalling pathway|upregulation of TNF-alpha-mediated signaling pathway|up-regulation of adipocytokine signaling pathway|up regulation of tumor necrosis factor-mediated signalling pathway|up regulation of tumor necrosis factor alpha-mediated signaling pathway|up-regulation of tumor necrosis factor alpha-mediated signaling pathway|upregulation of tumor necrosis factor-mediated signaling pathway|up regulation of TNF-alpha-mediated signaling pathway							bf	2014-08-07T10:26:59Z					biological_process											owl:Class	
GO:0045667	biolink:NamedThing	regulation of osteoblast differentiation	Any process that modulates the frequency, rate or extent of osteoblast differentiation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0005365	biolink:NamedThing	myo-inositol transmembrane transporter activity	Enables the transfer of myo-inositol from one side of a membrane to the other. Myo-inositol is 1,2,3,4,5/4,6-cyclohexanehexol, a growth factor for animals and microorganisms.	tmpzr1t_l9r_go_relaxed.owl	vitamin Bh transporter activity													molecular_function											owl:Class	
GO:0034940	biolink:NamedThing	5-oxo-4,5-dihydropyrrole-2-carboxylate amidase activity	Catalysis of the reaction: 5-oxo-4,5-dihydropyrrole-2-carboxylate + 2 H2O = 2-oxoglutarate + NH3.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0984									molecular_function											owl:Class	
GO:0033749	biolink:NamedThing	histone H3-methyl-arginine-3 demethylase activity	Catalysis of the removal of the methyl group from a modified arginine residue at position 3 of the histone H3 protein. This is a dioxygenase reaction that is dependent on Fe(II) and 2-oxoglutarate.	tmpzr1t_l9r_go_relaxed.owl	histone H3R3me demethylase activity|histone demethylase activity (H4-R3 specific)	https://github.com/geneontology/go-ontology/issues/21089												molecular_function											owl:Class	
GO:0035214	biolink:NamedThing	eye-antennal disc development	Progression of the eye-antennal imaginal disc over time, from its initial formation through to its metamorphosis to form adult structures including the eye, antenna, head capsule and maxillary palps.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0071583	biolink:NamedThing	negative regulation of zinc ion transmembrane transport	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of zinc ions (Zn2+) from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of zinc ion membrane transport							mah	2010-01-28T03:15:54Z					biological_process											owl:Class	
GO:0052096	biolink:NamedThing	formation of syncytium involving giant cell for nutrient acquisition	The assembly of a syncytium, a multi-nucleate and physiologically active aggregation of fused root cells induced by a symbiotic nematode in a plant host. The syncytium exclusively provides the nematode with nourishment during its sedentary life, for the purpose of obtaining nutrients from its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	formation by organism of syncytium involving giant cell for nutrient acquisition from host|formation by symbiont of syncytium involving giant cell for nutrient acquisition from host	https://github.com/geneontology/go-ontology/issues/20305												biological_process											owl:Class	
GO:0036228	biolink:NamedThing	protein localization to nuclear inner membrane	A process in which a protein is transported to, or maintained in, a location within the nuclear inner membrane.	tmpzr1t_l9r_go_relaxed.owl	protein targeting to nuclear inner membrane|protein targeting to INM							bf	2012-05-11T10:42:34Z					biological_process											owl:Class	
GO:0097442	biolink:NamedThing	CA3 pyramidal cell dendrite	A dendrite of a hippocampal CA3 pyramidal cell.	tmpzr1t_l9r_go_relaxed.owl					NIF_Subcellular:nlx_subcell_1005001			pr	2012-12-06T13:47:23Z					cellular_component											owl:Class	
GO:0009307	biolink:NamedThing	DNA restriction-modification system	A defense process found in many bacteria and archaea that protects the organism from invading foreign DNA by cleaving it with a restriction endonuclease. The organism's own DNA is protected by methylation of a specific nucleotide, which occurs immediately following replication, in the same target site as the restriction enzyme.	tmpzr1t_l9r_go_relaxed.owl	DNA restriction													biological_process											owl:Class	
GO:0004638	biolink:NamedThing	phosphoribosylaminoimidazole carboxylase activity	Catalysis of the reaction: 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + 2 H(+) = 5-amino-1-(5-phospho-D-ribosyl)imidazole + CO(2).	tmpzr1t_l9r_go_relaxed.owl	5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate carboxy-lyase activity|AIR carboxylase activity|class II PurE|5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate carboxy-lyase [5-amino-1-(5-phospho-D-ribosyl)imidazole-forming]|ADE2|5-amino-1-ribosylimidazole 5-phosphate carboxylase activity|1-(5-phosphoribosyl)-5-amino-4-imidazolecarboxylate carboxy-lyase activity|5-phosphoribosyl-5-aminoimidazole carboxylase activity				RHEA:10792|MetaCyc:AIRCARBOXY-RXN|EC:4.1.1.21|Reactome:R-HSA-73806|KEGG_REACTION:R04209									molecular_function											owl:Class	
GO:0042006	biolink:NamedThing	masculinization of hermaphroditic germ-line	The determination of male sex and sexual phenotype in the germ-line of the hermaphrodite. An example of this is found in Caenorhabditis elegans.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0070580	biolink:NamedThing	base J metabolic process	The chemical reactions and pathways involving base J (beta-D-glucosyl-hydroxymethyluracil), a hypermodified thymidine residue found in the genome of kinetoplastid parasites. This modified base is localized primarily to repetitive DNA, namely the telomeres, and is implicated in the regulation of antigenic variation. The base is synthesized in a two-step pathway. Initially, a thymidine residue in DNA is hydroxylated by a thymidine hydroxylase (TH) to form the intermediate hydroxymethyluracil, which is then glucosylated to form base J.	tmpzr1t_l9r_go_relaxed.owl	beta-D-glucosyl-hydroxymethyluracil metabolism|beta-D-glucosyl-HOMedU metabolic process|base J metabolism							mah	2009-04-22T02:37:23Z					biological_process											owl:Class	
GO:0047093	biolink:NamedThing	4-hydroxyquinoline 3-monooxygenase activity	Catalysis of the reaction: H(+) + NADH + O(2) + quinolin-4-ol = H(2)O + NAD(+) + quinoline-3,4-diol.	tmpzr1t_l9r_go_relaxed.owl	quinolin-4(1H)-one 3-monooxygenase activity|quinolin-4(1H)-one,NADH:oxygen oxidoreductase (3-oxygenating)|1-H-4-oxoquinoline 3-monooxygenase activity				EC:1.14.13.62|MetaCyc:1.14.13.62-RXN|KEGG_REACTION:R05154|RHEA:19325									molecular_function											owl:Class	
GO:0070883	biolink:NamedThing	pre-miRNA binding	Binding to a precursor microRNA (pre-miRNA) transcript, a stem-loop-containing precursor of microRNA.	tmpzr1t_l9r_go_relaxed.owl	precursor microRNA binding|pre-microRNA binding							mah	2009-08-24T04:36:24Z					molecular_function											owl:Class	
GO:0043796	biolink:NamedThing	glyceraldehyde dehydrogenase (NADP) activity	Catalysis of the reaction: D-glyceraldehyde + H2O + NADP+ = D-glycerate + NADPH + H+.	tmpzr1t_l9r_go_relaxed.owl					EC:1.2.1.89|RHEA:40163									molecular_function											owl:Class	
GO:0034573	biolink:NamedThing	didemethylisoproturon amidohydrolase activity	Catalysis of the reaction: didemethylisoproturon + H2O = carbamic acid + 4-isopropylaniline.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0898									molecular_function											owl:Class	
GO:0098974	biolink:NamedThing	postsynaptic actin cytoskeleton organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins in the postsynaptic actin cytoskeleton.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1901085	biolink:NamedThing	pyrrolizidine alkaloid biosynthetic process	The chemical reactions and pathways resulting in the formation of pyrrolizidine alkaloid.	tmpzr1t_l9r_go_relaxed.owl	pyrrolizidine alkaloid formation|pyrrolizidine alkaloid synthesis|pyrrolizidine alkaloid anabolism|pyrrolizidine alkaloid biosynthesis							yaf	2012-07-05T10:28:28Z					biological_process											owl:Class	
GO:0071707	biolink:NamedThing	immunoglobulin heavy chain V-D-J recombination	The process in which immunoglobulin heavy chain V, D, and J gene segments are recombined within a single locus utilizing the conserved heptamer and nonomer recombination signal sequences (RSS).	tmpzr1t_l9r_go_relaxed.owl	immunoglobulin V(D)J joining|immunoglobulin V-D-J joining|immunoglobulin V(D)J recombination							mah	2010-03-09T04:20:31Z					biological_process											owl:Class	
GO:0036307	biolink:NamedThing	23S rRNA (adenine(2030)-N(6))-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + adenine(2030) in 23S rRNA = S-adenosyl-L-homocysteine + rRNA containing N(6)-methyladenine(2030) in 23S rRNA.	tmpzr1t_l9r_go_relaxed.owl								bf	2012-08-08T14:15:48Z					molecular_function											owl:Class	
GO:0033748	biolink:NamedThing	hydrogenase (acceptor) activity	Catalysis of the reaction: H2 + A = AH2.	tmpzr1t_l9r_go_relaxed.owl	hydrogenlyase activity|uptake hydrogenase activity|H2 producing hydrogenase activity|hydrogen:(acceptor) oxidoreductase activity|hydrogen-lyase activity|hydrogen:acceptor oxidoreductase activity				MetaCyc:RXN0-5256|RHEA:12116|EC:1.12.99.6|MetaCyc:RXN0-4141									molecular_function											owl:Class	
GO:0032866	biolink:NamedThing	D-xylose:NADP reductase activity	Catalysis of the reaction: D-xylitol + NADP+ = D-xylose + NADPH + H+.	tmpzr1t_l9r_go_relaxed.owl	xylose reductase activity|D-xylose reductase activity				MetaCyc:RXN-8773|RHEA:27445									molecular_function											owl:Class	
GO:0072061	biolink:NamedThing	inner medullary collecting duct development	The process whose specific outcome is the progression of the inner medullary collecting duct over time, from its formation to the mature structure. The inner medullary collecting duct is the portion of the collecting duct that lies in the renal inner medulla.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-01-25T04:08:45Z					biological_process											owl:Class	
GO:0018519	biolink:NamedThing	cis-dihydroethylcatechol dehydrogenase activity	Catalysis of the reaction: cis-1,2-dihydro-3-ethylcatechol + NAD(+) = 3-ethylcatechol + H(+) + NADH.	tmpzr1t_l9r_go_relaxed.owl	cis-1,2-dihydro-3-ethylcatechol:NAD+ oxidoreductase activity|cis-ethylbenzene glycol dehydrogenase activity				UM-BBD_reactionID:r0309|RHEA:18101|KEGG_REACTION:R05313|EC:1.3.1.66|MetaCyc:1.3.1.66-RXN									molecular_function											owl:Class	
GO:0016711	biolink:NamedThing	flavonoid 3'-monooxygenase activity	Catalysis of the reaction: a flavonoid + NADPH + H+ + O2 = 3'-hydroxyflavonoid + NADP+ + H2O.	tmpzr1t_l9r_go_relaxed.owl	flavonoid,NADPH:oxygen oxidoreductase (3'-hydroxylating)|NADPH:flavonoid-3'-hydroxylase activity|flavonoid 3'-hydroxylase activity|flavonoid 3-monooxygenase|flavonoid 3-hydroxylase				EC:1.14.14.82|MetaCyc:FLAVONOID-3-MONOOXYGENASE-RXN|RHEA:16337									molecular_function											owl:Class	
GO:0000372	biolink:NamedThing	Group I intron splicing	The splicing of Group I introns. This occurs by a ribozymic mechanism where the intron sequence forms a distinct 3D structure, characteristic of Group I introns and involved in determining the locations of the splice sites (there do not appear to be consensus splice site sequences) as well as having a role in catalyzing the splicing reactions, though protein factors are also required in vivo. Splicing occurs by a series of two transesterification reactions, generally with exogenous guanosine as the initiating nucleophile. The intron is excised as a linear piece (though it may subsequently circularize).	tmpzr1t_l9r_go_relaxed.owl	mRNA splicing					Note that Group I introns are known to be found in a number of places: rRNA, mRNA, and tRNA in organelles of fungi, plants, and protists; tRNA and mRNA of bacteria and bacteriophage; rRNA of protists and fungi; and occasionally in mRNA of animal mitochondria (e.g. sea anemone).								biological_process											owl:Class	
GO:0004640	biolink:NamedThing	phosphoribosylanthranilate isomerase activity	Catalysis of the reaction: N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate.	tmpzr1t_l9r_go_relaxed.owl	PRA isomerase activity|PRAI activity|IGPS:PRAI (indole-3-glycerol-phosphate synthetase/N-5'-phosphoribosylanthranilate isomerase complex)|N-(5-phospho-beta-D-ribosyl)anthranilate aldose-ketose-isomerase activity|N-(5-phospho-beta-D-ribosyl)anthranilate ketol-isomerase activity|N-(5'-phosphoribosyl)anthranilate isomerase activity				EC:5.3.1.24|MetaCyc:PRAISOM-RXN|KEGG_REACTION:R03509|RHEA:21540									molecular_function											owl:Class	
GO:0032216	biolink:NamedThing	glucosaminyl-phosphatidylinositol O-acyltransferase activity	Catalysis of the reaction: glucosaminyl-phosphatidylinositol + fatty acyl-CoA = glucosaminyl-acyl-phasphotidylinositol + CoA.	tmpzr1t_l9r_go_relaxed.owl	glucosaminyl-phosphotidylinositol O-acyltransferase activity|GPI-inositol acyltransferase													molecular_function											owl:Class	
GO:0080146	biolink:NamedThing	L-cysteine desulfhydrase activity	Catalysis of the reaction: L-cysteine + H2O = ammonia + pyruvate + hydrogen sulfide + H+.	tmpzr1t_l9r_go_relaxed.owl					EC:4.4.1.1|RHEA:24931|Reactome:R-HSA-1614591|MetaCyc:LCYSDESULF-RXN|Reactome:R-HSA-1614614			dhl	2010-01-27T04:50:43Z					molecular_function											owl:Class	
GO:0031780	biolink:NamedThing	corticotropin hormone receptor binding	Binding to a corticotropin hormone receptor.	tmpzr1t_l9r_go_relaxed.owl	adrenocorticotropin hormone receptor binding|adrenocorticotropic hormone receptor ligand|ACTH receptor binding|corticotropin receptor binding|adrenocorticotropin receptor binding											GO:0071856		molecular_function											owl:Class	
GO:0003276	biolink:NamedThing	apoptotic process involved in heart valve morphogenesis	Any apoptotic process that contributes to the shaping of a heart valve.	tmpzr1t_l9r_go_relaxed.owl	apoptosis involved in heart valve morphogenesis							dph	2009-10-20T09:34:29Z					biological_process											owl:Class	
GO:0045952	biolink:NamedThing	regulation of juvenile hormone catabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of juvenile hormone.	tmpzr1t_l9r_go_relaxed.owl	regulation of juvenile hormone breakdown|regulation of juvenile hormone degradation|regulation of juvenile hormone catabolism													biological_process											owl:Class	
GO:0009042	biolink:NamedThing	valine-pyruvate transaminase activity	Catalysis of the reaction: L-valine + pyruvate = 3-methyl-2-oxobutanoate + L-alanine.	tmpzr1t_l9r_go_relaxed.owl	alanine--valine transaminase activity|alanine-oxoisovalerate aminotransferase activity|transaminase C activity|valine-pyruvate aminotransferase activity|valine--pyruvate aminotransferase activity|L-valine:pyruvate aminotransferase activity				RHEA:22912|EC:2.6.1.66|MetaCyc:VALINE-PYRUVATE-AMINOTRANSFER-RXN|KEGG_REACTION:R01215									molecular_function											owl:Class	
GO:0106291	biolink:NamedThing	superoxide-generating NADH oxidase activity.	Catalysis of the reaction: NADH + 2 O2 = H(+) + NAD(+) + 2 superoxide.	tmpzr1t_l9r_go_relaxed.owl					RHEA:63184			hjd	2020-08-19T15:56:43Z					molecular_function											owl:Class	
GO:1904288	biolink:NamedThing	BAT3 complex binding	Binding to a BAT3 complex.	tmpzr1t_l9r_go_relaxed.owl	BAT3-TRC35-UBL4A complex binding|BAG6-UBL4A-TRC35 complex binding|Bag6 complex binding							bf	2015-06-07T19:48:55Z					molecular_function											owl:Class	
GO:0106304	biolink:NamedThing	mannogen biosynthetic process	The chemical reactions and pathways resulting in the formation of mannogen, a mannose-containing polysaccharide that is a major energy reserve in Leishmania.	tmpzr1t_l9r_go_relaxed.owl	mannogen biosynthesis|mannogen formation|mannogen anabolism|beta-1,2-mannan biosynthetic process|mannogen synthesis							hjd	2020-09-09T13:52:26Z					biological_process											owl:Class	
GO:0033896	biolink:NamedThing	ribonuclease IX activity	Catalysis of the endonucleolytic cleavage of poly(U) or poly(C) to fragments terminated by 3'-hydroxy and 5'-phosphate groups.	tmpzr1t_l9r_go_relaxed.owl	poly(U)- and poly(C)-specific endoribonuclease activity				MetaCyc:3.1.26.10-RXN|EC:3.1.26.10									molecular_function											owl:Class	
GO:0080156	biolink:NamedThing	mitochondrial mRNA modification	The covalent alteration within the mitochondrion of one or more nucleotides within an mRNA to produce an mRNA molecule with a sequence that differs from that coded genetically.	tmpzr1t_l9r_go_relaxed.owl	mitochondrial mRNA editing|mitochondrial RNA editing							dhl	2010-09-01T03:55:48Z					biological_process											owl:Class	
GO:1901199	biolink:NamedThing	positive regulation of calcium ion transport into cytosol involved in cellular response to salt stress	Any positive regulation of calcium ion transport into cytosol that is involved in cellular response to salt stress.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of calcium ion transport into cytosol involved in cellular response to ionic osmotic stress|positive regulation of calcium ion transport into cytosol involved in cellular salinity response							al	2012-07-27T11:09:37Z					biological_process											owl:Class	
GO:0018759	biolink:NamedThing	methenyltetrahydromethanopterin cyclohydrolase activity	Catalysis of the reaction: 5,10-methenyl-5,6,7,8-tetrahydromethanopterin + H(2)O = N(5)-formyl-5,6,7,8-tetrahydromethanopterin + H(+).	tmpzr1t_l9r_go_relaxed.owl	N5,N10-methenyltetrahydromethanopterin cyclohydrolase activity|5,10-methenyltetrahydromethanopterin 10-hydrolase (decyclizing)|methenyl-H4MPT cyclohydrolase activity|5,10-methenyltetrahydromethanopterin cyclohydrolase activity|methenyl-H(4)MPT cyclohydrolase activity				RHEA:19053|MetaCyc:3.5.4.27-RXN|KEGG_REACTION:R03464|EC:3.5.4.27|UM-BBD_reactionID:r0347									molecular_function											owl:Class	
GO:0009365	biolink:NamedThing	protein histidine kinase complex	A complex that possesses protein histidine kinase activity.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0051478	biolink:NamedThing	mannosylglycerate metabolic process	The chemical reactions and pathways involving mannosylglycerate, a very common compatible solute in thermophilic and hyperthermophilic organisms.	tmpzr1t_l9r_go_relaxed.owl	mannosylglycerate metabolism													biological_process											owl:Class	
GO:0052572	biolink:NamedThing	response to host immune response	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detecting the immune response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	response to immune response of other organism involved in symbiotic interaction											GO:0052564		biological_process											owl:Class	
GO:0047670	biolink:NamedThing	anhydrotetracycline monooxygenase activity	Catalysis of the reaction: anhydrotetracycline + H(+) + NADPH + O(2) = 12-dehydrotetracycline + H(2)O + NADP(+).	tmpzr1t_l9r_go_relaxed.owl	ATC oxygenase activity|anhydrotetracycline,NADPH:oxygen oxidoreductase (6-hydroxylating)|anhydrotetracycline oxygenase activity				MetaCyc:ANHYDROTETRACYCLINE-MONOOXYGENASE-RXN|KEGG_REACTION:R04060|RHEA:11976|EC:1.14.13.38									molecular_function											owl:Class	
GO:0034991	biolink:NamedThing	nuclear meiotic cohesin complex	A cohesin complex that mediates sister chromatid cohesion in the nucleus during meiosis; has a subunit composition distinct from that of the mitotic cohesin complex.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0120230	biolink:NamedThing	recombinase activator activity	Binds to and increases the activity of a recombinase.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/19631|https://github.com/geneontology/go-ontology/issues/19555						krc	2020-06-18T15:54:26Z					molecular_function											owl:Class	
GO:0034139	biolink:NamedThing	regulation of toll-like receptor 3 signaling pathway	Any process that modulates the frequency, rate, or extent of toll-like receptor 3 signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	regulation of TLR3 signaling pathway|regulation of toll-like receptor 3 signalling pathway													biological_process											owl:Class	
GO:0010474	biolink:NamedThing	glucose-1-phosphate guanylyltransferase (GDP) activity	Catalysis of the reaction: GDP + D-glucose 1-phosphate = phosphate + GDP-glucose.	tmpzr1t_l9r_go_relaxed.owl	GDP:glucose-1-phosphate guanyltransferase activity													molecular_function											owl:Class	
GO:0016210	biolink:NamedThing	naringenin-chalcone synthase activity	Catalysis of the reaction: 3 malonyl-CoA + 4-coumaroyl-CoA = 4 CoA + naringenin chalcone + 3 CO2.	tmpzr1t_l9r_go_relaxed.owl	DOCS|malonyl-CoA:4-coumaroyl-CoA malonyltransferase (cyclizing)				RHEA:11128|EC:2.3.1.74|MetaCyc:NARINGENIN-CHALCONE-SYNTHASE-RXN									molecular_function											owl:Class	
GO:0097022	biolink:NamedThing	lymphocyte migration into lymph node	The movement of a lymphocyte within the lymphatic system into a lymph node, and its subsequent positioning within defined functional compartments such as sites of cell activation by antigen.	tmpzr1t_l9r_go_relaxed.owl	lymphocyte homing							pr	2011-03-29T04:29:27Z					biological_process											owl:Class	
GO:0097021	biolink:NamedThing	lymphocyte migration into lymphoid organs	The movement of a lymphocyte within the lymphatic system into lymphoid organs such as lymph nodes, spleen or Peyer's patches, and its subsequent positioning within defined functional compartments such as sites of cell activation by antigen.	tmpzr1t_l9r_go_relaxed.owl	lymphocyte homing							pr	2011-03-29T04:26:08Z					biological_process											owl:Class	
GO:1905223	biolink:NamedThing	epicardium morphogenesis	The developmental process by which an epicardium is generated and organized.	tmpzr1t_l9r_go_relaxed.owl	heart epicardium morphogenesis|visceral serous pericardium of heart morphogenesis|visceral serous pericardium proper morphogenesis|pericardium visceral mesothelium morphogenesis							rl	2016-06-07T10:02:32Z					biological_process											owl:Class	
GO:1905072	biolink:NamedThing	cardiac jelly development	The process whose specific outcome is the progression of cardiac jelly over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl	heart cardiac jelly development							rl	2016-03-23T13:17:59Z					biological_process											owl:Class	
GO:1904148	biolink:NamedThing	cellular response to nonylphenol	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nonylphenol stimulus.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-04-14T17:01:50Z					biological_process											owl:Class	
GO:0110056	biolink:NamedThing	positive regulation of actin filament annealing	Any process that activates or increases the frequency, rate or extent of actin filament annealing, i.e. the end-to-end joining of existing actin filaments.	tmpzr1t_l9r_go_relaxed.owl								kmv	2017-09-20T20:13:09Z					biological_process											owl:Class	
GO:0018777	biolink:NamedThing	1,3,4,6-tetrachloro-1,4-cyclohexadiene halidohydrolase activity	Catalysis of the reaction: alkyl halide + H2O = alcohol + HCl. Substrates are 1,3(R),4,6(R)-tetrachloro-1,4-cyclohexadiene (forms 2,4,5-trichloro-2,5-cyclohexadiene-1-ol) and 2,4,5-trichloro-2,5-cyclohexadiene-1-ol (forms 2,5-dichloro-2,5-cyclohexadiene-1,4-diol).	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0070502	biolink:NamedThing	capsule poly-gamma-glutamate biosynthetic process	The chemical reactions and pathways resulting in the formation of poly-gamma-glutamate, a polymer of D- and/or L-glutamic acid residues linked by gamma-peptidyl bonds, that forms all or part of a bacterial capsule.	tmpzr1t_l9r_go_relaxed.owl	capsule poly-gamma-glutamate formation|capsule poly-gamma-glutamate synthesis|capsule poly-gamma-glutamate anabolism|capsule poly-gamma-glutamate biosynthesis|capsular poly-gamma-glutamate biosynthetic process													biological_process											owl:Class	
GO:0030431	biolink:NamedThing	sleep	Any process in which an organism enters and maintains a periodic, readily reversible state of reduced awareness and metabolic activity. Usually accompanied by physical relaxation, the onset of sleep in humans and other mammals is marked by a change in the electrical activity of the brain.	tmpzr1t_l9r_go_relaxed.owl	diapause|lethargus|dormancy				Wikipedia:Sleep									biological_process											owl:Class	
GO:0061956	biolink:NamedThing	penetration of cumulus oophorus	The infiltration by sperm of the cumulus oophorus to reach the oocyte. The process involves digestive enzymes from a modified lysosome called the acrosome, situated at the head of the sperm.	tmpzr1t_l9r_go_relaxed.owl	penetration of cumulus mass|penetration of cumulus cells layer							dph	2017-11-10T20:14:18Z					biological_process											owl:Class	
GO:1904558	biolink:NamedThing	response to dextromethorphan	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dextromethorphan stimulus.	tmpzr1t_l9r_go_relaxed.owl								mr	2015-08-14T16:09:17Z					biological_process											owl:Class	
GO:0120164	biolink:NamedThing	conidium germination	The physiological and developmental changes that occur in a conidium or asexual spore following release from dormancy up to the earliest signs of development such as swelling of conidia, adhesion and nuclear decondensation followed by hyphal growth several hours later. In many genera of plant pathogenic fungi (e.g. Magnaporthe, Colletotrichum, Ustilago), swelling of the hyphal tips to form appressorium, metabolic activities including respiration, RNA and protein synthesis and trehalose breakdown and changes in cell wall composition can be detected in conidium germination.	tmpzr1t_l9r_go_relaxed.owl								krc	2018-05-17T17:03:32Z					biological_process											owl:Class	
GO:0033971	biolink:NamedThing	hydroxyisourate hydrolase activity	Catalysis of the reaction: 5-hydroxyisourate + H(2)O = 5-hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate + H(+).	tmpzr1t_l9r_go_relaxed.owl	HIUHase activity|5-hydroxyisourate hydrolase activity|5-hydroxyisourate amidohydrolase activity				MetaCyc:3.5.2.17-RXN|KEGG_REACTION:R06601|EC:3.5.2.17|RHEA:23736									molecular_function											owl:Class	
GO:0102699	biolink:NamedThing	2-methylpropionitrile hydroxylase activity	Catalysis of the reaction: H+ + 2-methylpropionitrile + O2 + NADPH <=> 2-hydroxy-2-methylpropanenitrile + NADP + H2O.	tmpzr1t_l9r_go_relaxed.owl					RHEA:51964|MetaCyc:RXN-5082									molecular_function											owl:Class	
GO:2001111	biolink:NamedThing	positive regulation of lens epithelial cell proliferation	Any process that activates or increases the frequency, rate or extent of lens epithelial cell proliferation.	tmpzr1t_l9r_go_relaxed.owl								yaf	2011-09-30T02:04:59Z					biological_process											owl:Class	
GO:0018237	biolink:NamedThing	urease activator activity	Increases the activity of urease by promoting the incorporation of nickel into the active site.	tmpzr1t_l9r_go_relaxed.owl	urease activase activity													molecular_function											owl:Class	
GO:0036266	biolink:NamedThing	Cdc48p-Npl4p-Vms1p AAA ATPase complex	A multiprotein ATPase complex involved in the release of polyubiquitinated proteins, including those damaged by oxidative stress, from the outer mitochondria membrane into the cytoplasm where they are presented to the proteasome for proteolysis, a process also referred to as mitochondria-associated degradation (MAD). In budding yeast, this complex includes Cdc48p, Npl4p and Vms1p.	tmpzr1t_l9r_go_relaxed.owl	Vms1p-Cdc48p-Npl4p complex|Cdc48p-Npl4p-Vms1p complex|Vms1-Cdc48-Npl4 complex							bf	2012-06-29T10:57:48Z					cellular_component											owl:Class	
GO:0102091	biolink:NamedThing	phosphatidylinositol-5-phosphate 5-phosphatase activity	Catalysis of the reaction: H2O + a 1-phosphatidyl-1D-myo-inositol 5-phosphate = hydrogenphosphate + an L-1-phosphatidyl-inositol.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-10962									molecular_function											owl:Class	
GO:0050273	biolink:NamedThing	S-succinylglutathione hydrolase activity	Catalysis of the reaction: S-succinylglutathione + H(2)O = glutathione + H(+) + succinate.	tmpzr1t_l9r_go_relaxed.owl					KEGG_REACTION:R00499|MetaCyc:S-SUCCINYLGLUTATHIONE-HYDROLASE-RXN|RHEA:16713|EC:3.1.2.13									molecular_function											owl:Class	
GO:0035831	biolink:NamedThing	palmatine biosynthetic process	The chemical reactions and pathways resulting in the formation of palmatine, a berberine alkaloid found in many plants.	tmpzr1t_l9r_go_relaxed.owl	palmatine anabolism|palmatine biosynthesis|palmatine formation|palmatine synthesis							bf	2011-05-04T03:06:06Z					biological_process											owl:Class	
GO:0043776	biolink:NamedThing	cobalt-precorrin-6B C5-methyltransferase activity	Catalysis of the reaction: S-adenosylmethionine + cobalt-precorrin 6B = S-adenosylhomocysteine + cobalt-precorrin 7.	tmpzr1t_l9r_go_relaxed.owl	precorrin-6Y methylase|precorrin-6 methyltransferase activity|cobalt-precorrin 6B C5-methyltransferase activity|precorrin-6Y C5,15-methyltransferase (decarboxylating)				MetaCyc:RXN-8766|RHEA:36067									molecular_function											owl:Class	
GO:0061899	biolink:NamedThing	11-cis-retinal 3,4-desaturase activity	Catalysis of the reaction: 11-cis-retinal + 2 H(+) + O2 + 2 reduced [adrenodoxin] = 11-cis-3,4-didehydro-retinal + 2 H2O + 2 oxidized [adrenodoxin].	tmpzr1t_l9r_go_relaxed.owl								dph	2017-06-12T15:03:57Z					molecular_function											owl:Class	
GO:0050423	biolink:NamedThing	thiamine oxidase activity	Catalysis of the reaction: thiamine + 2 O2 = thiamine acetic acid + 2 H2O2.	tmpzr1t_l9r_go_relaxed.owl	thiamin:oxygen 5-oxidoreductase activity|thiamine dehydrogenase activity|thiamin dehydrogenase activity|thiamine:oxygen 5-oxidoreductase activity|thiamin oxidase activity				RHEA:21280|EC:1.1.3.23|MetaCyc:THIAMIN-OXIDASE-RXN									molecular_function											owl:Class	
GO:0007042	biolink:NamedThing	lysosomal lumen acidification	Any process that reduces the pH of the lysosomal lumen, measured by the concentration of the hydrogen ion.	tmpzr1t_l9r_go_relaxed.owl	lysosome pH reduction													biological_process											owl:Class	
GO:0050505	biolink:NamedThing	hydroquinone glucosyltransferase activity	Catalysis of the reaction: hydroquinone + UDP-D-glucose = H(+) + hydroquinone O-beta-D-glucopyranoside + UDP.	tmpzr1t_l9r_go_relaxed.owl	arbutin synthase activity|UDP-glucose:hydroquinone-O-beta-D-glucosyltransferase activity|hydroquinone:O-glucosyltransferase activity|UDPglucose:hydroquinone-O-beta-D-glucosyltransferase activity				RHEA:12560|KEGG_REACTION:R05769|MetaCyc:2.4.1.218-RXN|EC:2.4.1.218									molecular_function											owl:Class	
GO:0030622	biolink:NamedThing	U4atac snRNA binding	Binding to a U4atac small nuclear RNA (U4atac snRNA).	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1902920	biolink:NamedThing	poly(hydroxyvalerate) metabolic process	The chemical reactions and pathways involving poly(hydroxyvalerate).	tmpzr1t_l9r_go_relaxed.owl	poly(hydroxyvalerate) metabolism							tt	2014-04-21T19:12:32Z					biological_process											owl:Class	
GO:0098530	biolink:NamedThing	positive regulation of strand invasion	Any process that increases the rate, frequency or extent of strand invasion. Strand invasion is the process in which the nucleoprotein complex (composed of the broken single-strand DNA and the recombinase) searches and identifies a region of homology in intact duplex DNA. The broken single-strand DNA displaces the like strand and forms Watson-Crick base pairs with its complement, forming a duplex in which each strand is from one of the two recombining DNA molecules.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of D-loop formation|positive regulation of Rad51-mediated strand invasion|positive regulation of D-loop biosynthesis							dos	2013-10-16T12:15:59Z					biological_process											owl:Class	
GO:0047629	biolink:NamedThing	ADP deaminase activity	Catalysis of the reaction: ADP + H2O = IDP + NH3.	tmpzr1t_l9r_go_relaxed.owl	adenosine diphosphate deaminase activity|adenosinepyrophosphate deaminase activity|ADP aminohydrolase activity				RHEA:12741|EC:3.5.4.7|MetaCyc:ADP-DEAMINASE-RXN									molecular_function											owl:Class	
GO:1990564	biolink:NamedThing	protein polyufmylation	Covalent attachment of the ubiquitin-like protein UFM1 to a protein, forming an UFM1 chain.	tmpzr1t_l9r_go_relaxed.owl								jl	2014-11-26T14:15:36Z					biological_process											owl:Class	
GO:0071569	biolink:NamedThing	protein ufmylation	Covalent attachment of the ubiquitin-like protein UFM1 to another protein.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-01-20T04:12:01Z					biological_process											owl:Class	
GO:0072637	biolink:NamedThing	interleukin-32 production	The appearance of interleukin-32 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	tmpzr1t_l9r_go_relaxed.owl	interleukin-32 biosynthetic process|IL-32 production|NK4 production|TAIF production|interleukin-32 secretion|IL32 production							bc	2020-02-21T10:26:40Z			GO:0150188|GO:0072638		biological_process											owl:Class	
GO:0030060	biolink:NamedThing	L-malate dehydrogenase activity	Catalysis of the reaction: (S)-malate + NAD+ = oxaloacetate + NADH + H+.	tmpzr1t_l9r_go_relaxed.owl	(S)-malate:NAD+ oxidoreductase activity|malic dehydrogenase activity|NAD-malate dehydrogenase activity|NAD-linked malate dehydrogenase activity|MDH|NAD-dependent malic dehydrogenase activity|malic acid dehydrogenase activity|L-malate-NAD+ oxidoreductase activity|NAD-L-malate dehydrogenase activity|malate (NAD) dehydrogenase activity|NAD-dependent malate dehydrogenase activity|NAD-malic dehydrogenase activity|NAD-specific malate dehydrogenase activity				MetaCyc:MALATE-DEH-RXN|EC:1.1.1.37|Reactome:R-HSA-198508|Reactome:R-HSA-70979|RHEA:21432|Reactome:R-HSA-71783									molecular_function											owl:Class	
GO:0060691	biolink:NamedThing	epithelial cell maturation involved in salivary gland development	The developmental process, independent of morphogenetic (shape) change, that is required for an epithelial cell of the salivary gland to attain its fully functional state.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-06-08T01:06:00Z					biological_process											owl:Class	
GO:1990180	biolink:NamedThing	mitochondrial tRNA 3'-end processing	The process in which the 3' end of a pre-tRNA molecule is converted to that of a mature tRNA in the mitochondrion.	tmpzr1t_l9r_go_relaxed.owl	tRNA 3' processing in mitochondria|tRNA 3'-end processing in mitochondria|tRNA 3' processing in mitochondrion							mah	2013-08-30T16:17:36Z					biological_process											owl:Class	
GO:0047215	biolink:NamedThing	indole-3-acetate beta-glucosyltransferase activity	Catalysis of the reaction: (indol-3-yl)acetate + UDP-D-glucose = 1-O-(indol-3-ylacetyl)-beta-D-glucose + UDP.	tmpzr1t_l9r_go_relaxed.owl	UDPG-indol-3-ylacetyl glucosyl transferase activity|UDP-glucose:indol-3-acetic acid glucosyltransferase activity|indol-3-ylacetylglucose synthase activity|UDP-glucose:auxin glucosyltransferase activity|UDP-glucose:(indol-3-yl)acetate beta-D-glucosyltransferase activity|UDP-glucose:indol-3-ylacetate glucosyl-transferase activity|IAA-Glu synthetase activity|uridine diphosphoglucose-indoleacetate glucosyltransferase activity|IAGlu synthase activity|UDPglucose:indole-3-acetate beta-D-glucosyltransferase activity|IAA-glucose synthase activity|UDP-glucose:indol-3-ylacetate glucosyltransferase activity				KEGG_REACTION:R03094|MetaCyc:2.4.1.121-RXN|RHEA:14921|EC:2.4.1.121									molecular_function											owl:Class	
GO:0060813	biolink:NamedThing	anterior mRNA localization involved in anterior/posterior axis specification	Any process in which a mRNA is transported to, and maintained in the anterior portion of the oocyte and/or syncytial embryo contributing to the specification of the anterior/posterior axis.	tmpzr1t_l9r_go_relaxed.owl	anterior mRNA localisation involved in anterior/posterior axis specification							dph	2009-08-07T09:51:47Z					biological_process											owl:Class	
GO:0008124	biolink:NamedThing	4-alpha-hydroxytetrahydrobiopterin dehydratase activity	Catalysis of the reaction: (6R)-6-(L-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4a-hydroxypterin = (6R)-6-(L-erythro-1,2-dihydroxypropyl)-7,8-dihydro-6H-pterin + H(2)O.	tmpzr1t_l9r_go_relaxed.owl	4alpha-hydroxy-tetrahydropterin dehydratase activity|4a-hydroxytetrahydrobiopterin dehydratase activity|pterin-4-alpha-carbinolamine dehydratase activity|pterin-4alpha-carbinolamine dehydratase activity|4-alpha-hydroxy-tetrahydropterin dehydratase activity|tetrahydrobiopterin dehydratase activity|4a-hydroxytetrahydrobiopterin hydro-lyase activity|pterin-4a-carbinolamine dehydratase activity|(6R)-6-(L-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4a-hydroxypterin hydro-lyase [(6R)-6-(L-erythro-1,2-dihydroxypropyl)-7,8-dihydro-6H-pterin-forming]				RHEA:11920|KEGG_REACTION:R04734|MetaCyc:RXN-7908|EC:4.2.1.96|Reactome:R-HSA-71146									molecular_function											owl:Class	
GO:0034606	biolink:NamedThing	response to hermaphrodite contact	The response by the male to a hermaphrodite after initial contact following mate finding. The male stops forward locomotion, presses the ventral side of his tail against his partner's body, and begins moving backward along the hermaphrodite. Male response behavior is initiated when sensory neurons located in the rays of his tail contact a potential mate.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0042608	biolink:NamedThing	T cell receptor binding	Binding to a T cell receptor, the antigen-recognizing receptor on the surface of T cells.	tmpzr1t_l9r_go_relaxed.owl	T-cell receptor binding|T-lymphocyte receptor binding|TCR binding|T lymphocyte receptor binding													molecular_function											owl:Class	
GO:1901784	biolink:NamedThing	p-cresol metabolic process	The chemical reactions and pathways involving p-cresol.	tmpzr1t_l9r_go_relaxed.owl	p-cresol metabolism							yaf	2013-01-16T11:03:59Z					biological_process											owl:Class	
GO:0009631	biolink:NamedThing	cold acclimation	Any process that increases freezing tolerance of an organism in response to low, nonfreezing temperatures.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0106358	biolink:NamedThing	glycerol-1-phosphate dehydrogenase [NADP+] activity	Catalysis of the reaction: NADP+ + sn-glycerol 1-phosphate = dihydroxyacetone phosphate + H+ + NADPH.	tmpzr1t_l9r_go_relaxed.owl					RHEA:21416			hjd	2021-02-02T06:08:14Z					molecular_function											owl:Class	
GO:0050492	biolink:NamedThing	glycerol-1-phosphate dehydrogenase [NAD(P)+] activity	Catalysis of the reaction: NAD(P)+ + sn-glycerol-1-phosphate = NAD(P)H + H+ + dihydroxy-acetone-phosphate.	tmpzr1t_l9r_go_relaxed.owl	sn-glycerol-1-phosphate:NAD(P)+ 2-oxidoreductase activity				MetaCyc:1.1.1.261-RXN|EC:1.1.1.261									molecular_function											owl:Class	
GO:0042500	biolink:NamedThing	aspartic endopeptidase activity, intramembrane cleaving	Catalysis of the hydrolysis of nonterminal peptide bonds in a polypeptide chain, occurring within a membrane.	tmpzr1t_l9r_go_relaxed.owl					EC:3.4.23.-|Reactome:R-HSA-8863101	Note that although GO generally avoids the use of localization information in terms, in this case an exception was made. This is because the fact that the cleavage occurs within the membrane is integral to its function, as it is the only thing that distinguishes this group from other aspartic endopeptidases.								molecular_function											owl:Class	
GO:0070402	biolink:NamedThing	NADPH binding	Binding to the reduced form, NADPH, of nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions.	tmpzr1t_l9r_go_relaxed.owl	reduced nicotinamide adenine dinucleotide phosphate binding|reduced NADP binding|NADP (reduced) binding													molecular_function											owl:Class	
GO:0021790	biolink:NamedThing	chemorepulsion of branchiomotor neuron axon in branchial arch mesenchyme	The process in which a branchiomotor neuron growth cone in the branchial arch mesenchyme is directed to a specific target site in the branchial arch mesenchyme in response to a repulsive chemical cue. Branchiomotor neurons are located in the hindbrain and innervate branchial arch-derived muscles that control jaw movements, facial expression, the larynx, and the pharynx.	tmpzr1t_l9r_go_relaxed.owl	negative chemotaxis of branchiomotor neuron axon in branchial arch mesenchyme													biological_process											owl:Class	
GO:0103118	biolink:NamedThing	UDP-3-O-(R-3-hydroxymyristoyl)-glucosamine N-acyltransferase activity	Catalysis of the reaction: UDP-3-O-[(3R)-3-hydroxytetradecanoyl]-alpha-D-glucosamine(1-) + an (3R)-3-hydroxymyristoyl-[acp] <=> UDP-2,3-bis[O-(3R)-3-hydroxymyristoyl]-alpha-D-glucosamine + H+ + a holo-[acyl-carrier protein].	tmpzr1t_l9r_go_relaxed.owl	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase activity				MetaCyc:UDPHYDROXYMYRGLUCOSAMNACETYLTRANS-RXN|EC:2.3.1.191|RHEA:17817							GO:0043764		molecular_function											owl:Class	
GO:0019074	biolink:NamedThing	viral RNA genome packaging	The packaging of viral RNA (single-stranded or double-stranded) into a nucleocapsid.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0003692	biolink:NamedThing	left-handed Z-DNA binding	Binding to DNA in the Z form, i.e. a left-handed helix in which the phosphate backbone zigzags.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1905904	biolink:NamedThing	positive regulation of mesoderm formation	Any process that activates or increases the frequency, rate or extent of mesoderm formation.	tmpzr1t_l9r_go_relaxed.owl	activation of mesoderm formation|up regulation of mesoderm formation|up-regulation of mesoderm formation|upregulation of mesoderm formation							rph	2017-02-03T12:28:38Z					biological_process											owl:Class	
GO:2000382	biolink:NamedThing	positive regulation of mesoderm development	Any process that activates or increases the frequency, rate or extent of mesoderm development.	tmpzr1t_l9r_go_relaxed.owl								vk	2011-02-15T03:10:12Z					biological_process											owl:Class	
GO:0007258	biolink:NamedThing	JUN phosphorylation	The process of introducing a phosphate group into a JUN protein.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0000338	biolink:NamedThing	protein deneddylation	The removal of a ubiquitin-like protein of the NEDD8 type from a protein.	tmpzr1t_l9r_go_relaxed.owl	cullin deneddylation											GO:0010388		biological_process											owl:Class	
GO:0004027	biolink:NamedThing	alcohol sulfotransferase activity	Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + an alcohol = adenosine 3',5'-bisphosphate + an alkyl sulfate.	tmpzr1t_l9r_go_relaxed.owl	hydroxysteroid sulfotransferase activity|delta5-3beta-hydroxysteroid sulfokinase activity|HST|3'-phosphoadenylyl-sulfate:alcohol sulfotransferase activity|alcohol sulphotransferase activity|3beta-hydroxy steroid sulfotransferase activity|steroid sulfokinase activity|steroid alcohol sulfotransferase|alcohol/hydroxysteroid sulfotransferase activity|sterol sulfotransferase activity|5alpha-androstenol sulfotransferase activity|3-hydroxysteroid sulfotransferase activity|3beta-hydroxysteroid sulfotransferase activity|estrogen sulfokinase activity|sterol sulfokinase activity|dehydroepiandrosterone sulfotransferase activity|estrogen sulfotransferase				EC:2.8.2.2|Reactome:R-HSA-176609|MetaCyc:ALCOHOL-SULFOTRANSFERASE-RXN|Reactome:R-HSA-176494|RHEA:22552									molecular_function											owl:Class	
GO:0098724	biolink:NamedThing	symmetric stem cell division	Symmetric division of a stem cell to produce two stem cells of the same type as the parent. Symmetric stem cell division is necessary for amplification of stem cell populations in the absence of sources of stem cells external to an existing population.	tmpzr1t_l9r_go_relaxed.owl						Examples include the self-renewal of spermatogonial stem cells and (some) division during amplification of skeletal muscle satellite cell populations.								biological_process											owl:Class	
GO:0102714	biolink:NamedThing	gibberellin A12,oxoglutarate:oxygen oxidoreductase activity	Catalysis of the reaction: gibberellin A12 + 2-oxoglutarate + O2 <=> gibberellin A14 + succinate + carbon dioxide.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-6544									molecular_function											owl:Class	
GO:0070952	biolink:NamedThing	regulation of neutrophil mediated killing of gram-positive bacterium	Any process that modulates the rate, frequency or extent of neutrophil mediated killing of a gram-positive bacterium, the directed killing of a gram-positive bacterium by a neutrophil.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-10-01T02:14:36Z					biological_process											owl:Class	
GO:0018009	biolink:NamedThing	N-terminal peptidyl-L-cysteine N-palmitoylation	The covalent attachment of a palmitoyl group to a nitrogen (N) atom in an N-terminal cysteine residue to form N-palmitoyl-L-cysteine.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0060									biological_process											owl:Class	
GO:0050250	biolink:NamedThing	retinal oxidase activity	Catalysis of the reaction: retinal + O2 + H2O = retinoate + H2O2.	tmpzr1t_l9r_go_relaxed.owl	retinene oxidase activity|retinal:oxygen oxidoreductase activity				RHEA:22520|MetaCyc:RETINAL-OXIDASE-RXN|EC:1.2.3.11									molecular_function											owl:Class	
GO:0070338	biolink:NamedThing	5'-flap-structured DNA binding	Binding to a 5'-flap structure in DNA. A DNA flap structure is one in which a single-stranded 5'-end of DNA or RNA protrudes from a double-stranded DNA molecule. 5'-flap structures can be formed during DNA repair or lagging strand synthesis; in the latter case RNA flaps form from lagging strand RNA primers.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1900086	biolink:NamedThing	positive regulation of peptidyl-tyrosine autophosphorylation	Any process that activates or increases the frequency, rate or extent of peptidyl-tyrosine autophosphorylation.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of tyrosine autophosphorylation|activation of receptor tyrosine kinase autophosphorylation|up-regulation of peptidyl-tyrosine autophosphorylation|upregulation of tyrosine autophosphorylation|upregulation of peptidyl-tyrosine autophosphorylation|activation of peptidyl-tyrosine autophosphorylation|up regulation of peptidyl-tyrosine autophosphorylation|positive regulation of tyrosine autophosphorylation|up-regulation of receptor tyrosine kinase autophosphorylation|activation of tyrosine autophosphorylation|positive regulation of receptor tyrosine kinase autophosphorylation|up regulation of tyrosine autophosphorylation|upregulation of receptor tyrosine kinase autophosphorylation|up regulation of receptor tyrosine kinase autophosphorylation							bf	2012-02-03T10:17:15Z					biological_process											owl:Class	
GO:0035753	biolink:NamedThing	maintenance of DNA trinucleotide repeats	Any process involved in sustaining the fidelity and copy number of DNA trinucleotide repeats. DNA trinucleotide repeats are naturally occurring runs of three base-pairs.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-03-23T10:29:02Z					biological_process											owl:Class	
GO:0075053	biolink:NamedThing	penetration peg formation	The assembly by the symbiont of a peg-like structure for the purpose of penetration into its host organism, which penetrates through the host cuticle and epidermal cell wall. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	initiation of symbiont penetration peg|symbiont penetration peg formation for entry into host|symbiont penetration peg initiation|formation of symbiont penetration peg for entry into host	https://github.com/geneontology/go-ontology/issues/18557				Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products from the symbiont involved in this process.						GO:0075057		biological_process											owl:Class	
GO:0003127	biolink:NamedThing	detection of nodal flow	The series of events by which an endogenous stimulus is received by a cilium on a cell and converted to a molecular signal contributing to left/right asymmetry.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-09-22T02:45:48Z					biological_process											owl:Class	
GO:0030661	biolink:NamedThing	chitosome membrane	The lipid bilayer surrounding a chitosome.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0044807	biolink:NamedThing	macrophage migration inhibitory factor production	The appearance of macrophage migration inhibitory factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	tmpzr1t_l9r_go_relaxed.owl	MIF production							jl	2013-09-11T12:04:09Z					biological_process											owl:Class	
GO:0090284	biolink:NamedThing	positive regulation of protein glycosylation in Golgi	Any process that increases the rate, frequency, or extent of the addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid in any compartment of the Golgi apparatus.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of protein amino acid glycosylation in Golgi							tb	2010-02-18T02:43:55Z					biological_process											owl:Class	
GO:0039716	biolink:NamedThing	viroplasm viral factory	A cytoplasmic viral factory that is electron dense due to high levels of viral RNA. Produced by nucleo-cytoplasmic large DNA viruses (NCLDV) like Poxviridae, Asfarviridae and Iridoviridae, and dsRNA viruses like Reoviridae.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Viroplasm			bf	2013-12-19T15:22:29Z					cellular_component											owl:Class	
GO:0034016	biolink:NamedThing	polyenoic fatty acid isomerase activity	Catalysis of the reaction: all-cis-icosa-5,8,11,14,17-pentaenoate = (5Z,7E,9E,14Z,17Z)-icosapentaenoate.	tmpzr1t_l9r_go_relaxed.owl	(5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate delta8,11-delta7,9-isomerase (trans-double-bond-forming) activity|(5Z,8Z,11Z,14Z,17Z)-icosapentaenoate delta8,11-delta7,9-isomerase (trans-double-bond-forming) activity|(5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate delta8,11-delta7,8-isomerase activity|eicosapentaenoate cis-delta5,8,11,14,17-eicosapentaenoate cis-delta5-trans-delta7,9-cis-delta14,17 isomerase activity|PFI				KEGG_REACTION:R06502|EC:5.3.3.13|MetaCyc:5.3.3.13-RXN|RHEA:14889									molecular_function											owl:Class	
GO:0071703	biolink:NamedThing	detection of organic substance	The series of events in which an organic substance stimulus is received by a cell and converted into a molecular signal.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-03-08T03:18:44Z					biological_process											owl:Class	
GO:0036211	biolink:NamedThing	protein modification process	The covalent alteration of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications). Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification).	tmpzr1t_l9r_go_relaxed.owl	protein modification							bf	2012-04-26T01:47:12Z					biological_process											owl:Class	
GO:0007280	biolink:NamedThing	pole cell migration	The directed movement of a pole cell (germline progenitors in insects) from its site of production at the posterior pole of the embryo through to the site where the gonads will form.	tmpzr1t_l9r_go_relaxed.owl						See also the Cell Ontology term 'pole cell ; CL:0000301'.								biological_process											owl:Class	
GO:0008683	biolink:NamedThing	2-oxoglutarate decarboxylase activity	Catalysis of the reaction: 2-oxoglutarate + H(+) = CO(2) + succinate semialdehyde.	tmpzr1t_l9r_go_relaxed.owl	2-oxoglutarate carboxy-lyase activity|alpha-ketoglutaric decarboxylase activity|2-oxoglutarate carboxy-lyase (succinate-semialdehyde-forming)|pre-2-oxoglutarate decarboxylase activity|alpha-ketoglutarate decarboxylase activity				RHEA:10524|MetaCyc:RXN-7774|EC:4.1.1.71|KEGG_REACTION:R00272									molecular_function											owl:Class	
GO:0034531	biolink:NamedThing	2-hydroxy-4-hydroxymethylbenzalpyruvate hydratase-aldolase activity	Catalysis of the reaction: 2-hydroxy-4-hydroxymethylbenzalpyruvate + H2O = pyruvate + 4-hydroxymethylsalicylaldehyde.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0766									molecular_function											owl:Class	
GO:0106262	biolink:NamedThing	1-acylglycerophosphoethanolamine O-acyltransferase activity	Catalysis of the reaction: a 1-acyl-sn-glycero-3-phosphoethanolamine + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + CoA.	tmpzr1t_l9r_go_relaxed.owl					RHEA:32995			hjd	2020-05-18T15:09:57Z					molecular_function											owl:Class	
GO:1900548	biolink:NamedThing	heme B catabolic process	The chemical reactions and pathways resulting in the breakdown of heme b, a Fe(II) porphyrin complex readily isolated from the hemoglobin of beef blood, but also found in other proteins including other hemoglobins, myoglobins, cytochromes P-450, catalases, peroxidases as well as b type cytochromes.	tmpzr1t_l9r_go_relaxed.owl	protoheme catabolic process|heme B breakdown|heme B degradation|protoheme degradation|heme B catabolism				MetaCyc:PWY-5874			pr	2012-05-14T12:35:18Z					biological_process											owl:Class	
GO:0046492	biolink:NamedThing	heme B metabolic process	The chemical reactions and pathways involving heme b, a Fe(II) porphyrin complex readily isolated from the hemoglobin of beef blood, but also found in other proteins including other hemoglobins, myoglobins, cytochromes P-450, catalases, peroxidases as well as b type cytochromes.	tmpzr1t_l9r_go_relaxed.owl	haem B metabolism|protoheme metabolism|heme B metabolism|haem B metabolic process|protoheme metabolic process													biological_process											owl:Class	
GO:0006425	biolink:NamedThing	glutaminyl-tRNA aminoacylation	The process of coupling glutamine to glutaminyl-tRNA, catalyzed by glutaminyl-tRNA synthetase. The glutaminyl-tRNA synthetase is a  class-I synthetase. The activated amino acid is transferred to the 2'-OH group of a glutamine-accetping tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0031480	biolink:NamedThing	myosin X complex	A myosin complex containing one or more class X myosin heavy chains and associated light chains.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:1901277	biolink:NamedThing	tartrate biosynthetic process	The chemical reactions and pathways resulting in the formation of tartrate.	tmpzr1t_l9r_go_relaxed.owl	tartrate anabolism|tartrate biosynthesis|tartrate synthesis|tartrate formation							yaf	2012-08-17T14:52:48Z					biological_process											owl:Class	
GO:0018610	biolink:NamedThing	dibenzofuran 4,4a-dioxygenase activity	Catalysis of the reaction: dibenzofuran + NADH + H+ + O2 = 2,2',3-trihydroxybiphenyl + NAD+.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_enzymeID:e0030|MetaCyc:R606-RXN|RHEA:42460									molecular_function											owl:Class	
GO:0042169	biolink:NamedThing	SH2 domain binding	Binding to a SH2 domain (Src homology 2) of a protein, a protein domain of about 100 amino-acid residues and belonging to the alpha + beta domain class.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0008831	biolink:NamedThing	dTDP-4-dehydrorhamnose reductase activity	Catalysis of the reaction: dTDP-6-deoxy-L-mannose + NADP(+) = dTDP-4-dehydro-6-deoxy-L-mannose + H(+) + NADPH.	tmpzr1t_l9r_go_relaxed.owl	dTDP-4-ketorhamnose reductase activity|thymidine diphospho-4-ketorhamnose reductase activity|TDP-4-keto-rhamnose reductase activity|dTDP-6-deoxy-L-mannose:NADP+ 4-oxidoreductase activity|dTDP-6-deoxy-L-mannose dehydrogenase activity|dTDP-4-keto-L-rhamnose reductase activity|reductase, thymidine diphospho-4-ketorhamnose				RHEA:21796|MetaCyc:DTDPDEHYRHAMREDUCT-RXN|EC:1.1.1.133|KEGG_REACTION:R02777									molecular_function											owl:Class	
GO:0047200	biolink:NamedThing	tetrahydrodipicolinate N-acetyltransferase activity	Catalysis of the reaction: (S)-2,3,4,5-tetrahydrodipicolinate + acetyl-CoA + H(2)O = L-2-acetamido-6-oxopimelate + CoA.	tmpzr1t_l9r_go_relaxed.owl	acetyl-CoA:(S)-2,3,4,5-tetrahydrodipicolinate-2,6-dicarboxylate N2-acetyltransferase activity|tetrahydrodipicolinate:acetyl-CoA acetyltransferase activity|acetyl-CoA:L-2,3,4,5-tetrahydrodipicolinate N2-acetyltransferase activity|tetrahydrodipicolinate acetylase activity|acetyl-CoA:(S)-2,3,4,5-tetrahydropyridine-2,6-dicarboxylate 2-N-acetyltransferase activity				MetaCyc:2.3.1.89-RXN|KEGG_REACTION:R04364|RHEA:13085|EC:2.3.1.89									molecular_function											owl:Class	
GO:0018847	biolink:NamedThing	alpha-pinene lyase activity	Catalysis of the reaction: alpha-pinene = limonene.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0712|EC:5.5.1.-									molecular_function											owl:Class	
GO:0007228	biolink:NamedThing	positive regulation of hh target transcription factor activity	Any process that increases the activity of a transcription factor that activates transcription of Hedgehog-target genes in response to Smoothened signaling. In Drosophila, Cubitus interruptus (Ci) is the only identified transcription factor so far in the Hedgehog signaling pathway. In vertebrates, members of the Gli protein family are activated in this way. Activation of the Gli/Ci transcription factor is distinct from its stabilization, when proteolytic cleavage is inhibited.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of hedgehog target transcription factor|activation of hh target transcription factor													biological_process											owl:Class	
GO:1901545	biolink:NamedThing	response to raffinose	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a raffinose stimulus.	tmpzr1t_l9r_go_relaxed.owl								al	2012-10-26T14:32:23Z					biological_process											owl:Class	
GO:0045679	biolink:NamedThing	regulation of R8 cell differentiation	Any process that modulates the frequency, rate or extent of R8 differentiation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0016217	biolink:NamedThing	N-ethylammeline chlorohydrolase activity	Catalysis of the reaction: deethylsimazine + H2O = N-ethylammeline + chloride + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:R465-RXN									molecular_function											owl:Class	
GO:0009756	biolink:NamedThing	carbohydrate mediated signaling	A series of molecular signals mediated by the detection of carbohydrate.	tmpzr1t_l9r_go_relaxed.owl	carbohydrate mediated signalling													biological_process											owl:Class	
GO:0010296	biolink:NamedThing	prenylcysteine methylesterase activity	Catalysis of the reaction: protein C-terminal S-farnesyl-L-cysteine methyl ester + H2O = protein C-terminal S-farnesyl-L-cysteine + methanol + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-8409|RHEA:48520									molecular_function											owl:Class	
GO:0004106	biolink:NamedThing	chorismate mutase activity	Catalysis of the reaction: chorismate = prephenate.	tmpzr1t_l9r_go_relaxed.owl	chorismate pyruvatemutase activity|hydroxyphenylpyruvate synthase activity				KEGG_REACTION:R01715|RHEA:13897|MetaCyc:CHORISMATEMUT-RXN|EC:5.4.99.5									molecular_function											owl:Class	
GO:0018082	biolink:NamedThing	peptidyl-(Z)-dehydrobutyrine biosynthetic process from peptidyl-threonine	The formation of (Z)-dehydrobutyrine by the dehydration of peptidyl-threonine.	tmpzr1t_l9r_go_relaxed.owl	peptidyl-(Z)-dehydrobutyrine formation from peptidyl-threonine|peptidyl-(Z)-dehydrobutyrine anabolism from peptidyl-threonine|peptidyl-(Z)-dehydrobutyrine synthesis from peptidyl-threonine				RESID:AA0182									biological_process											owl:Class	
GO:0007508	biolink:NamedThing	larval heart development	The process whose specific outcome is the progression of the larval heart over time, from its formation to the mature structure. In Drosophila the larval heart (dorsal vessel) is a continuous tube of mesodormal cells that runs beneath the dorsal midline of the epidermis, divided into an anterior aorta and a posterior heart proper.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0097389	biolink:NamedThing	chemokine (C-C motif) ligand 21 production	The appearance of chemokine (C-C motif) ligand 21 (CCL21) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	tmpzr1t_l9r_go_relaxed.owl	CCL21 production							pr	2012-10-23T07:56:26Z					biological_process											owl:Class	
GO:0003396	biolink:NamedThing	cell adhesion involved in amphid sensory organ dendrite retrograde extension	The directed, self-propelled movement of a neuron that contributes to the process of retrograde extension of a dendrite in a neuron of the amphid sensory organ.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-12-09T09:50:18Z					biological_process											owl:Class	
GO:1903412	biolink:NamedThing	response to bile acid	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bile acid stimulus.	tmpzr1t_l9r_go_relaxed.owl								rl	2014-09-03T12:45:43Z					biological_process											owl:Class	
GO:0080077	biolink:NamedThing	trihydroxyferuloyl spermidine:S-adenosyl-L-methionine O-methyltransferase activity	Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to the oxygen atom of a trihydroxyferuloyl spermidine molecule.	tmpzr1t_l9r_go_relaxed.owl								dhl	2009-04-14T04:00:45Z					molecular_function											owl:Class	
GO:1990893	biolink:NamedThing	mitotic chromosome centromere condensation	The cell cycle process in which centromere chromatin structure is compacted prior to and during mitosis.	tmpzr1t_l9r_go_relaxed.owl	mitotic chromosome condensation at kinetochore							vw	2015-11-03T14:26:29Z					biological_process											owl:Class	
GO:1901936	biolink:NamedThing	beta-caryophyllene catabolic process	The chemical reactions and pathways resulting in the breakdown of beta-caryophyllene.	tmpzr1t_l9r_go_relaxed.owl	beta-caryophyllene degradation|beta-caryophyllene catabolism|beta-caryophyllene breakdown							ms	2013-02-18T14:55:13Z					biological_process											owl:Class	
GO:0034513	biolink:NamedThing	box H/ACA snoRNA binding	Binding to a box H/ACA small nucleolar RNA.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0033853	biolink:NamedThing	aspartate-prephenate aminotransferase activity	Catalysis of the reaction: L-arogenate + oxaloacetate = prephenate + L-aspartate.	tmpzr1t_l9r_go_relaxed.owl	PAT|L-aspartate:prephenate aminotransferase activity|prephenate transaminase activity|prephenate aspartate aminotransferase activity|L-arogenate:oxaloacetate aminotransferase activity				EC:2.6.1.78|RHEA:20445|MetaCyc:PREPHENATE-ASP-TRANSAMINE-RXN									molecular_function											owl:Class	
GO:1902497	biolink:NamedThing	iron-sulfur cluster transmembrane transport	A process in which an iron-sulfur cluster is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	iron-sulfur cluster transport							dph	2013-11-13T16:33:00Z					biological_process											owl:Class	
GO:0098782	biolink:NamedThing	mechanosensitived potassium channel activity	Enables the transmembrane transfer of a potassium ion by a channel that opens in response to a mechanical stress.	tmpzr1t_l9r_go_relaxed.owl	mechanically-gated potassium channel activity													molecular_function											owl:Class	
GO:0038019	biolink:NamedThing	Wnt receptor recycling	The process that results in the return of a Wnt receptor to an active state at the plasma membrane. An active state is when the receptor is ready to receive a Wnt signal. Internalized Wnt receptors can be recycled to the plasma membrane or sorted to lysosomes for protein degradation.	tmpzr1t_l9r_go_relaxed.owl	Frizzled recycling							bf	2011-06-23T04:46:11Z					biological_process											owl:Class	
GO:0015762	biolink:NamedThing	rhamnose transmembrane transport	The process in which rhamnose is transported across a lipid bilayer, from one side of a membrane to the other. Rhamnose occurs commonly as a compound of plant glycosides, in polysaccharides of gums and mucilages, and in bacterial polysaccharides. It is also a component of some plant cell wall polysaccharides and frequently acts as the sugar components of flavonoids.	tmpzr1t_l9r_go_relaxed.owl	rhamnose transport													biological_process											owl:Class	
GO:2001087	biolink:NamedThing	sophorose transport	The directed movement of a sophoroseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl								jl	2011-09-21T12:58:08Z					biological_process											owl:Class	
GO:0018745	biolink:NamedThing	epoxide hydrolase A activity	Catalysis of the hydrolysis of the ether in chloro-, bromo- or hydroxyepoxypropane to produce a chloro- or bromopropane diol or glycerol.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_enzymeID:e0049|EC:3.3.2.-									molecular_function											owl:Class	
GO:0070068	biolink:NamedThing	VAMP4-syntaxin-6-syntaxin-16-Vti1a complex	A SNARE complex that contains VAMP4, syntaxin 6, syntaxin 16, and Vti1a (or orthologs thereof).	tmpzr1t_l9r_go_relaxed.owl	Vamp4-Stx6-Stx16-Vti1a complex|SNARE complex (Vamp4, Stx6, Stx16, Vti1a)													cellular_component											owl:Class	
GO:0010012	biolink:NamedThing	steroid 22-alpha hydroxylase activity	Catalysis of the reaction: 5-alpha-campestanaol + O2 = 6-deoxocathasterone + H2O.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0097474	biolink:NamedThing	retinal cone cell apoptotic process	Any apoptotic process in a retinal cone cell, one of the two photoreceptor cell types of the vertebrate retina.	tmpzr1t_l9r_go_relaxed.owl	cone photoreceptor apoptotic process							pr	2013-03-21T09:46:22Z					biological_process											owl:Class	
GO:0098533	biolink:NamedThing	ATPase dependent transmembrane transport complex	A transmembrane protein complex that functions in ATPase dependent active transport across a membrane.	tmpzr1t_l9r_go_relaxed.owl						The location of this complex is implicit in its activity, so its location is asserted as a regular relationship rather than as a part of an intersection.		dos	2013-10-22T12:12:52Z					cellular_component											owl:Class	
GO:0052682	biolink:NamedThing	epi-cedrol synthase activity	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate + H2O = epi-cedrol + diphosphate.	tmpzr1t_l9r_go_relaxed.owl	epicedrol synthase activity|8-epicedrol synthase activity|(2E,6E)-farnesyl-diphosphate diphosphate-lyase (8-epi-cedrol-forming) activity				KEGG_REACTION:R09140|EC:4.2.3.39|RHEA:26115|MetaCyc:RXN-10004									molecular_function											owl:Class	
GO:0015702	biolink:NamedThing	chlorate transport	The directed movement of chlorate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0085017	biolink:NamedThing	entry into host cell by a symbiont-containing vacuole	The invasion by a symbiont of a cell of a host organism, forming a vacuole in which the symbiont resides. The vacuole membrane is formed from lipids and proteins derived from both host and symbiont. Begins when the symbiont attaches on to the host cell membrane which invaginates and deepens as the symbiont enters, and ends when the host cell membrane closes behind the newly-formed vacuole.	tmpzr1t_l9r_go_relaxed.owl	symbiont entry into host cell forming a parasitophorous vacuole|symbiont entry into host cell forming a symbiont-containing vacuole|symbiont entry into host cell forming a pathogen-containing vacuole							jl	2010-05-20T02:55:34Z			GO:0052370		biological_process											owl:Class	
GO:0047355	biolink:NamedThing	CDP-glycerol glycerophosphotransferase activity	Catalysis of the reaction: glycerophosphate(n) + CDP-glycerol = glycerophosphate(n+1) + CMP.	tmpzr1t_l9r_go_relaxed.owl	CDPglycerol glycerophosphotransferase activity|poly(glycerol phosphate) polymerase activity|cytidine diphosphoglycerol glycerophosphotransferase activity|teichoic-acid synthase activity|teichoic acid glycerol transferase activity|glycerophosphate synthetase activity|CGPTase activity|CDP-glycerol:poly(glycerophosphate) glycerophosphotransferase activity				MetaCyc:2.7.8.12-RXN|RHEA:13565|EC:2.7.8.12									molecular_function											owl:Class	
GO:1901115	biolink:NamedThing	erythromycin biosynthetic process	The chemical reactions and pathways resulting in the formation of erythromycin.	tmpzr1t_l9r_go_relaxed.owl	erythromycin biosynthesis|erythromycin synthesis|erythromycin anabolism|erythromycin formation							yaf	2012-07-11T03:06:46Z					biological_process											owl:Class	
GO:0050440	biolink:NamedThing	2-methylcitrate synthase activity	Catalysis of the reaction: H(2)O + oxaloacetate + propanoyl-CoA = (2R,3S)-2-methylcitrate + CoA + H(+).	tmpzr1t_l9r_go_relaxed.owl	methylcitrate synthase activity|2-methylcitrate oxaloacetate-lyase activity|methylcitrate synthetase activity|propanoyl-CoA:oxaloacetate C-propanoyltransferase (thioester-hydrolysing, 1-carboxyethyl-forming)|MCS activity				MetaCyc:2-METHYLCITRATE-SYNTHASE-RXN|RHEA:23780|KEGG_REACTION:R00931|EC:2.3.3.5									molecular_function											owl:Class	
GO:0046981	biolink:NamedThing	beta-1,4-mannosylglycolipid beta-1,3-N-acetylglucosaminyltransferase activity	Catalysis of the transfer of N-acetylglucosamine (GlcNAc) in a beta-1,3 linkage to the mannose(beta-1,4)Glc disaccharide core of glycolipids.	tmpzr1t_l9r_go_relaxed.owl	UDP-N-acetylglucosamine:beta-D-mannosyl-glycolipid beta-1,3-N-acetylglucosaminyltransferase activity													molecular_function											owl:Class	
GO:1990617	biolink:NamedThing	CHOP-ATF4 complex	A heterodimeric transcription factor complex that is composed of CHOP (C/EBP homology protein, GADD153) and ATF4 (activating transcription factor 4, also known as cAMP response element binding protein-2/CREB-2) subunits.	tmpzr1t_l9r_go_relaxed.owl	ATF4-CHOP heterodimer|CHOP-CREB-2 complex|CHOP-ATF4 heterodimer|GADD153-ATF4 complex|CHOP/ATF4 complex							bf	2015-01-22T11:29:51Z					cellular_component											owl:Class	
GO:0030107	biolink:NamedThing	HLA-A specific inhibitory MHC class I receptor activity	Combining with a MHC class I molecule of the HLA-A subclass to mediate signaling that inhibits activation of a lymphocyte.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0048772	biolink:NamedThing	leucophore differentiation	The process in which a relatively unspecialized cell acquires the specialized features of a leucophore cell. Leucophores are pigment cells derived from the neural crest. They contain uric acid or other purine crystals, deposited in stacks called leucosomes. This gives them a white appearance.	tmpzr1t_l9r_go_relaxed.owl	leucophore cell differentiation													biological_process											owl:Class	
GO:0097366	biolink:NamedThing	response to bronchodilator	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bronchodilator stimulus. A bronchodilator is a chemical that causes an increase in the expansion of a bronchus or bronchial tubes.	tmpzr1t_l9r_go_relaxed.owl	response to broncholytic agent|response to bronchodilator agent					Note that this term is in the subset of terms that should not be used for direct manual annotation of gene products. It was created to be used for cross-referencing by other ontologies. Direct annotations to this term may be amended during annotation QC.		pr	2012-08-01T16:13:31Z					biological_process											owl:Class	
GO:1990805	biolink:NamedThing	central cylinder	A scaffolding structure present within the inner region of the ciliary transition zone. The central cylinder lies between the outer doublet and inner singlet microtubules.	tmpzr1t_l9r_go_relaxed.owl								kmv	2015-07-17T17:48:17Z					cellular_component											owl:Class	
GO:0002947	biolink:NamedThing	tumor necrosis factor receptor superfamily complex	A receptor complex that contains one or more members of the tumor necrosis factor (TNF) receptor superfamily.	tmpzr1t_l9r_go_relaxed.owl	TNF receptor superfamily complex							hjd	2012-12-20T13:26:39Z					cellular_component											owl:Class	
GO:0006683	biolink:NamedThing	galactosylceramide catabolic process	The chemical reactions and pathways resulting in the breakdown of galactosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of galactose by a ceramide group.	tmpzr1t_l9r_go_relaxed.owl	galactosylceramide catabolism|galactosylceramide degradation|galactosylceramide breakdown													biological_process											owl:Class	
GO:0102157	biolink:NamedThing	(R)-sulfopropanediol 2-dehydrogenase activity	Catalysis of the reaction: (2R)-3-sulfopropanediol(1-) + NAD <=> 2-oxo-3-hydroxy-propane-1-sulfonate + NADH + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-11729									molecular_function											owl:Class	
GO:0050225	biolink:NamedThing	pseudouridine kinase activity	Catalysis of the reaction: ATP + pseudouridine = ADP + 2 H(+) + pseudouridine 5'-phosphate.	tmpzr1t_l9r_go_relaxed.owl	ATP:pseudouridine 5'-phosphotransferase activity|pseudouridine kinase (phosphorylating)				RHEA:22448|KEGG_REACTION:R03315|MetaCyc:PSEUDOURIDINE-KINASE-RXN|EC:2.7.1.83									molecular_function											owl:Class	
GO:0050661	biolink:NamedThing	NADP binding	Binding to nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions; binding may be to either the oxidized form, NADP+, or the reduced form, NADPH.	tmpzr1t_l9r_go_relaxed.owl	NADP or NADPH binding|nicotinamide adenine dinucleotide phosphate binding|NADP+ or NADPH binding													molecular_function											owl:Class	
GO:0071576	biolink:NamedThing	tetrahydrodictyopterin binding	Binding to tetrahydrodictyopterin, the pterin 2-amino-6-[(1R,2R)-1,2-dihydroxypropyl]-5,6,7,8-tetrahydropteridin-4(3H)-one.	tmpzr1t_l9r_go_relaxed.owl	D-threo-tetrahydrobiopterin|DH4 binding							mah	2010-01-26T05:24:59Z					molecular_function											owl:Class	
GO:0008788	biolink:NamedThing	alpha,alpha-phosphotrehalase activity	Catalysis of the reaction: alpha,alpha-trehalose 6-phosphate + H2O = D-glucose + D-glucose 6-phosphate.	tmpzr1t_l9r_go_relaxed.owl	trehalose-6-phosphate hydrolase activity|alpha,alpha-trehalose-6-phosphate phosphoglucohydrolase activity|phosphotrehalase activity				MetaCyc:TRE6PHYDRO-RXN|EC:3.2.1.93|RHEA:23008									molecular_function											owl:Class	
GO:0044417	biolink:NamedThing	translocation of molecules into host	The directed movement of a molecule(s) produced by an organism to a location inside its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	translocation of molecules into other organism during symbiotic interaction|transport of molecules into other organism during symbiotic interaction|translocation of molecules into other organism involved in symbiotic interaction|transport of molecules into host											GO:0051836		biological_process											owl:Class	
GO:0046265	biolink:NamedThing	thiocyanate catabolic process	The chemical reactions and pathways resulting in the breakdown of thiocyanate, any anion of thiocyanic acid.	tmpzr1t_l9r_go_relaxed.owl	thiocyanate degradation|thiocyanate breakdown|thiocyanate catabolism													biological_process											owl:Class	
GO:0150142	biolink:NamedThing	positive regulation of CD86 production	Any process that activates or increases the frequency, rate or extent of CD86 biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of CD86 biosynthetic process							bc	2019-12-08T09:35:35Z					biological_process											owl:Class	
GO:0031412	biolink:NamedThing	gas vesicle organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a gas vesicle. A gas vesicle is a hollow structure made of protein, which usually has the form of a cylindrical tube closed by conical end caps.	tmpzr1t_l9r_go_relaxed.owl	gas vesicle formation|gas vesicle organization and biogenesis|gas vesicle organisation|gas vesicle biosynthesis					Note that although gas vesicles are commonly referred to as 'vesicles' or 'vacuoles' in the literature, they are not surrounded by a membrane.								biological_process											owl:Class	
GO:0017062	biolink:NamedThing	respiratory chain complex III assembly	The aggregation, arrangement and bonding together of a set of components to form the cytochrome bc(1) complex, a transmembrane lipoprotein complex that it catalyzes the reduction of cytochrome c by accepting reducing equivalents from Coenzyme Q, by the aggregation, arrangement and bonding together of its constituents.	tmpzr1t_l9r_go_relaxed.owl	cytochrome bc(1) complex assembly|coenzyme Q and cytochrome c reductase complex biogenesis|coenzyme Q and cytochrome c reductase complex assembly|complex III assembly|complex III biogenesis|cytochrome bc(1) complex biogenesis													biological_process											owl:Class	
GO:0004667	biolink:NamedThing	prostaglandin-D synthase activity	Catalysis of the reaction: prostaglandin H(2) = prostaglandin D(2).	tmpzr1t_l9r_go_relaxed.owl	prostaglandin D2 synthase activity|(5,13)-(15S)-9alpha,11alpha-epidioxy-15-hydroxyprosta-5,13-dienoate D-isomerase activity|PGH-PGD isomerase activity|prostaglandin-R-prostaglandin D isomerase activity|prostaglandin-H2 D-isomerase activity|PGD2 synthase activity				EC:5.3.99.2|MetaCyc:PROSTAGLANDIN-D-SYNTHASE-RXN|RHEA:10600|KEGG_REACTION:R02266|Reactome:R-HSA-2161701|Reactome:R-HSA-2161620									molecular_function											owl:Class	
GO:0048487	biolink:NamedThing	beta-tubulin binding	Binding to the microtubule constituent protein beta-tubulin.	tmpzr1t_l9r_go_relaxed.owl	beta tubulin binding													molecular_function											owl:Class	
GO:0006265	biolink:NamedThing	DNA topological change	The process in which a transformation is induced in the topological structure of a double-stranded DNA helix, resulting in a change in linking number.	tmpzr1t_l9r_go_relaxed.owl	DNA underwinding					Note that the synonym 'DNA underwinding' should not be confused with 'DNA unwinding ; GO:0006268', which refers to DNA strand separation, and is a type of geometric change. GO:0006265 refers to alteration of the superhelical density of double-stranded DNA. Note that DNA topological change and DNA geometric change (GO:0032392) are distinct, but are usually coupled in vivo.								biological_process											owl:Class	
GO:0070193	biolink:NamedThing	synaptonemal complex organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a synaptonemal complex. A synaptonemal complex is a proteinaceous scaffold formed between homologous chromosomes during meiosis.	tmpzr1t_l9r_go_relaxed.owl	synaptonemal complex organisation													biological_process											owl:Class	
GO:0061816	biolink:NamedThing	proteaphagy	The selective autophagy process that clears 26S proteasomes; homeostatic mechanism within the ubiquitin system that modulates proteolytic capacity and eliminates damaged particles.	tmpzr1t_l9r_go_relaxed.owl								dph	2016-12-01T20:21:28Z					biological_process											owl:Class	
GO:0090687	biolink:NamedThing	activation of meiosis I spindle assembly checkpoint	Any process that starts the inactive process of a meiosis I cell cycle spindle assembly checkpoint.	tmpzr1t_l9r_go_relaxed.owl								tb	2016-07-20T16:49:17Z					biological_process											owl:Class	
GO:0043398	biolink:NamedThing	HLH domain binding	Binding to a Helix Loop Helix domain, a domain of 40-50 residues that occurs in specific DNA-binding proteins that act as transcription factors. The domain is formed of two amphipathic helices joined by a variable length linker region that can form a loop and it mediates protein dimerization.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0032444	biolink:NamedThing	activin responsive factor complex	A transcriptionally active complex that binds to an activin response element (ARE) in the promoter of target genes, and is composed of two SMAD2 proteins, one SMAD4 protein and a Forkhead activin signal transducer (FAST) transcription factor.	tmpzr1t_l9r_go_relaxed.owl	ARF complex					Note that this term should not be confused with any of the molecular function and biological process terms that refer to the small GTPase ARF (ADP-ribosylation factor).								cellular_component											owl:Class	
GO:0009248	biolink:NamedThing	K antigen biosynthetic process	The chemical reactions and pathways resulting in the formation of a K antigen, a capsular polysaccharide antigen carried on the surface of bacterial capsules that masks somatic (O) antigens.	tmpzr1t_l9r_go_relaxed.owl	K antigen synthesis|K antigen formation|K antigen biosynthesis|K antigen anabolism													biological_process											owl:Class	
GO:1903920	biolink:NamedThing	positive regulation of actin filament severing	Any process that activates or increases the frequency, rate or extent of actin filament severing.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of F-actin severing|upregulation of actin filament severing|up regulation of actin filament severing|upregulation of F-actin severing|upregulation of actin filament severing activity|activation of actin filament severing|positive regulation of actin filament severing activity|activation of barbed-end actin capping/severing activity|upregulation of barbed-end actin capping/severing activity|up-regulation of F-actin severing|up regulation of actin filament severing activity|up-regulation of actin filament severing activity|up-regulation of actin filament severing|up regulation of barbed-end actin capping/severing activity|activation of F-actin severing|positive regulation of barbed-end actin capping/severing activity|up regulation of F-actin severing|up-regulation of barbed-end actin capping/severing activity|activation of actin filament severing activity							als	2015-02-10T11:01:40Z					biological_process											owl:Class	
GO:1905006	biolink:NamedThing	negative regulation of epithelial to mesenchymal transition involved in endocardial cushion formation	Any process that stops, prevents or reduces the frequency, rate or extent of epithelial to mesenchymal transition involved in endocardial cushion formation.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of epithelial to mesenchymal transition involved in endocardial cushion formation|inhibition of epithelial to mesenchymal transition involved in endocardial cushion formation|downregulation of epithelial to mesenchymal transition involved in endocardial cushion formation|down regulation of epithelial to mesenchymal transition involved in endocardial cushion formation							rl	2016-03-01T15:38:47Z					biological_process											owl:Class	
GO:0002950	biolink:NamedThing	ceramide phosphoethanolamine synthase activity	Catalysis of the reaction: CDP-ethanolamine + a ceramide = CMP + a ceramide phosphoethanolamine.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-8959462			hjd	2016-08-16T13:41:21Z					molecular_function											owl:Class	
GO:1903486	biolink:NamedThing	establishment of mitotic actomyosin contractile ring localization	Any establishment of actomyosin contractile ring localization that is involved in mitotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl	establishment of actomyosin contractile ring localization involved in mitotic cell cycle							vw	2014-09-23T16:17:09Z					biological_process											owl:Class	
GO:0080104	biolink:NamedThing	5-methylthiopropyl glucosinolate S-oxygenase activity	Catalysis of the reaction: 5-methylthiopropyl-glucosinolate = 5-methylsulfinylpropyl-glucosinolate.	tmpzr1t_l9r_go_relaxed.owl								dhl	2009-04-23T04:28:25Z					molecular_function											owl:Class	
GO:0030744	biolink:NamedThing	luteolin O-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + luteolin = 4',5,7-trihydroxy-3'-methoxyflavone + S-adenosyl-L-homocysteine + H(+).	tmpzr1t_l9r_go_relaxed.owl	luteolin 3'-O-methyltransferase activity|S-adenosylmethionine:flavone/flavonol 3'-O-methyltransferase activity|o-dihydric phenol meta-O-methyltransferase activity|o-dihydric phenol methyltransferase activity|luteolin methyltransferase activity|o-diphenol m-O-methyltransferase activity|S-adenosyl-L-methionine:5,7,3',4'-tetrahydroxyflavone 3'-O-methyltransferase activity				RHEA:14589|MetaCyc:LUTEOLIN-O-METHYLTRANSFERASE-RXN|KEGG_REACTION:R03587|EC:2.1.1.42									molecular_function											owl:Class	
GO:0106033	biolink:NamedThing	spine synapse	A type of synapse occurring between an axon and a dendritic spine.	tmpzr1t_l9r_go_relaxed.owl	dendritic spine synapse							hjd	2017-07-05T19:20:48Z					cellular_component											owl:Class	
GO:0102051	biolink:NamedThing	indole-3-acetyl-tryptophan synthetase activity	Catalysis of the reaction: indole-3-acetate + L-tryptophan + ATP(4-) <=> H+ + indole-3-acetyl-tryptophan + AMP(2-) + diphosphoric acid.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-10433									molecular_function											owl:Class	
GO:0034373	biolink:NamedThing	intermediate-density lipoprotein particle remodeling	The acquisition, loss or modification of a protein or lipid within an intermediate-density lipoprotein particle.	tmpzr1t_l9r_go_relaxed.owl	LDL formation|IDL remodeling|low-density lipoprotein particle formation													biological_process											owl:Class	
GO:0019714	biolink:NamedThing	peptidyl-glutamine esterification	The addition of an ester group to a glutamine residue in a protein.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0018070	biolink:NamedThing	peptidyl-serine phosphopantetheinylation	The phosphopantetheinylation of peptidyl-serine to form peptidyl-O-phosphopantetheine-L-serine.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0150									biological_process											owl:Class	
GO:0045735	biolink:NamedThing	nutrient reservoir activity	Functions in the storage of nutritious substrates.	tmpzr1t_l9r_go_relaxed.owl	yolk protein|storage protein of fat body|storage protein					Note that this term can be used in place of the obsolete terms 'storage protein ; GO:0005187' and 'storage protein of fat body (sensu Insecta) ; GO:0008041'.								molecular_function											owl:Class	
GO:0043953	biolink:NamedThing	protein transport by the Tat complex	The process in which folded proteins are transported across cytoplasmic membranes of bacteria and membranes of organelles derived from bacteria (chloroplasts and mitochondria) by the TAT complex.	tmpzr1t_l9r_go_relaxed.owl	protein translocation by the twin-arginine translocation complex|protein translocation by the TAT complex|twin-arginine translocation pathway|protein secretion by the TAT complex					Note that this term represents an activity and not a cellular structure. Consider also annotating to the cellular structure term 'TAT protein translocation system complex ; GO:0033281'. Note that this term is used for annotation of proteins that compose the transport complex but not the proteins being transported.								biological_process											owl:Class	
GO:0019933	biolink:NamedThing	cAMP-mediated signaling	Any intracellular signal transduction in which the signal is passed on within the cell via cyclic AMP (cAMP). Includes production of cAMP, and downstream effectors that further transmit the signal within the cell.	tmpzr1t_l9r_go_relaxed.owl	cAMP-mediated signal transduction|cAMP-mediated signalling|adenosine 3',5'-cyclophosphate-mediated signaling|cAMP signalling|3',5'-cAMP-mediated signaling|cyclic AMP-mediated signaling|cyclic AMP-mediated signalling|3',5' cAMP-mediated signaling|3',5'-cAMP-mediated signalling|3',5' cAMP-mediated signalling|adenosine 3',5'-cyclophosphate-mediated signalling|cAMP signaling													biological_process											owl:Class	
GO:0008659	biolink:NamedThing	(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity	Catalysis of the reaction: (3R)-3-hydroxytetradecanoyl-[acyl-carrier protein] = tetradecenoyl-[acyl-carrier protein] + H2O.	tmpzr1t_l9r_go_relaxed.owl	(3R)-hydroxymyristoyl-[acyl-carrier protein] dehydratase activity|(3R)-hydroxymyristoyl-ACP dehydratase activity				RHEA:41892|EC:4.2.1.59									molecular_function											owl:Class	
GO:0072354	biolink:NamedThing	histone kinase activity (H3-T3 specific)	Catalysis of the transfer of a phosphate group to the threonine-3 residue of the N-terminal tail of histone H3.	tmpzr1t_l9r_go_relaxed.owl	histone threonine kinase activity (H3-T3 specific)|histone-threonine kinase activity (H3-T3 specific)							mah	2010-11-12T04:27:57Z					molecular_function											owl:Class	
GO:1900927	biolink:NamedThing	negative regulation of L-threonine import across plasma membrane	Any process that stops, prevents or reduces the frequency, rate or extent of L-threonine import into cell.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of L-threonine import|downregulation of L-threonine uptake|inhibition of L-threonine uptake|down regulation of L-threonine uptake|inhibition of L-threonine import|downregulation of L-threonine import|negative regulation of L-threonine uptake|down regulation of L-threonine import|down-regulation of L-threonine uptake							al	2012-06-13T07:41:52Z					biological_process											owl:Class	
GO:0047180	biolink:NamedThing	salutaridinol 7-O-acetyltransferase activity	Catalysis of the reaction: (7S)-salutaridinol + acetyl-CoA = (7S)-O-acetylsalutaridinol + CoA.	tmpzr1t_l9r_go_relaxed.owl	acetyl-CoA:salutaridinol 7-O-acetyltransferase activity				EC:2.3.1.150|KEGG_REACTION:R04723|MetaCyc:2.3.1.150-RXN|RHEA:22856									molecular_function											owl:Class	
GO:0003861	biolink:NamedThing	3-isopropylmalate dehydratase activity	Catalysis of the reaction: (2R,3S)-3-isopropylmalate = (2S)-2-isopropylmalate.	tmpzr1t_l9r_go_relaxed.owl	isopropylmalate isomerase activity|(2R,3S)-3-isopropylmalate hydro-lyase activity|alpha-IPM isomerase activity|beta-isopropylmalate dehydratase activity|alpha-isopropylmalate isomerase activity|(2R,3S)-3-isopropylmalate hydro-lyase (2-isopropylmaleate-forming)				MetaCyc:3-ISOPROPYLMALISOM-RXN|RHEA:32287|EC:4.2.1.33									molecular_function											owl:Class	
GO:0035101	biolink:NamedThing	FACT complex	An abundant nuclear complex, which was originally identified in mammalian systems as a factor required for transcription elongation on chromatin templates. The FACT complex has been shown to destablilize the interaction between the H2A/H2B dimer and the H3/H4 tetramer of the nucleosome, thus reorganizing the structure of the nucleosome. In this way, the FACT complex may play a role in DNA replication and other processes that traverse the chromatin, as well as in transcription elongation. FACT is composed of two proteins that are evolutionarily conserved in all eukaryotes and homologous to mammalian Spt16 and SSRP1. In metazoans, the SSRP1 homolog contains an HMG domain; however in fungi and protists, it does not. For example, in S. cerevisiae the Pob3 protein is homologous to SSRP1, but lacks the HMG chromatin binding domain. Instead, the yFACT complex of Spt16p and Pob3p, binds to nucleosomes where multiple copies of the HMG-domain containing protein Nhp6p have already bound, but Nhp6p does not form a stable complex with the Spt16p/Pob3p heterodimer.	tmpzr1t_l9r_go_relaxed.owl	Facilitates chromatin transcription complex	https://github.com/geneontology/go-ontology/issues/19572												cellular_component											owl:Class	
GO:0003292	biolink:NamedThing	cardiac septum cell differentiation	The process in which an endocardial cushion cell becomes a cell of a cardiac septum.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-10-20T11:03:46Z					biological_process											owl:Class	
GO:0004435	biolink:NamedThing	phosphatidylinositol phospholipase C activity	Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H(2)O = 1,2-diacylglycerol + 1D-myo-inositol 1,4,5-trisphosphate + H(+).	tmpzr1t_l9r_go_relaxed.owl	phosphoinositidase C activity|1-phosphatidyl-1D-myo-inositol-4,5-bisphosphate inositoltrisphosphohydrolase activity|1-phosphatidyl-D-myo-inositol-4,5-bisphosphate inositoltrisphosphohydrolase activity|1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase activity|triphosphoinositide phosphodiesterase activity|phosphoinositide phospholipase C activity|monophosphatidylinositol phosphodiesterase activity|phosphatidylinositol-4,5-bisphosphate hydrolysis|PI-PLC activity				Reactome:R-HSA-9032478|EC:3.1.4.11|Reactome:R-HSA-1855214|Reactome:R-HSA-111879|RHEA:33179|Reactome:R-HSA-1855177|MetaCyc:3.1.4.11-RXN|Reactome:R-HSA-2730847|Reactome:R-HSA-202407|Reactome:R-HSA-167686|Reactome:R-HSA-1855221|Reactome:R-HSA-622382|KEGG_REACTION:R03435|Reactome:R-HSA-5607735									molecular_function											owl:Class	
GO:0030782	biolink:NamedThing	(S)-tetrahydroprotoberberine N-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + (S)-7,8,13,14-tetrahydroprotoberberine = S-adenosyl-L-homocysteine + cis-N-methyl-(S)-7,8,13,14-tetrahydroprotoberberine.	tmpzr1t_l9r_go_relaxed.owl	S-adenosyl-L-methionine:(S)-7,8,13,14-tetrahydroprotoberberine cis-N-methyltransferase activity|tetrahydroprotoberberine cis-N-methyltransferase activity				RHEA:12805|MetaCyc:2.1.1.122-RXN|EC:2.1.1.122									molecular_function											owl:Class	
GO:0103096	biolink:NamedThing	CYP79F1 dihomomethionine monooxygenase activity	Catalysis of the reaction: dihomomethionine + 2 O2 + 2 NADPH + 2 H+ <=> 5-methylthiopentanaldoxime + 3 H2O + carbon dioxide + 2 NADP.	tmpzr1t_l9r_go_relaxed.owl					RHEA:32719|MetaCyc:RXNQT-4309									molecular_function											owl:Class	
GO:0010216	biolink:NamedThing	maintenance of DNA methylation	Any process involved in maintaining the methylation state of a nucleotide sequence.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1990727	biolink:NamedThing	tubulin folding cofactor complex	A multimeric protein complex involved in tubulin alpha-beta-subunit folding assembly consisting of beta-tubulin-TFC-D, alpha-tubulin-TFC-E and TFC-C, through which tubulin subunit association and dimer release occur.	tmpzr1t_l9r_go_relaxed.owl								pr	2015-04-08T10:29:43Z					cellular_component											owl:Class	
GO:0060903	biolink:NamedThing	positive regulation of meiosis I	Any process that increases the rate, frequency, or extent of meiosis I, a cell cycle process comprising the steps by which a cell progresses through the first phase of meiosis, in which cells divide and homologous chromosomes are paired and segregated from each other, producing two daughter cells.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-08-14T01:06:57Z					biological_process											owl:Class	
GO:0018462	biolink:NamedThing	4-(hydroxymethyl)benzenesulfonate dehydrogenase activity	Catalysis of the reaction: 4-(hydroxymethyl)benzenesulfonate + NAD(+) = 4-formylbenzenesulfonate + H(+) + NADH.	tmpzr1t_l9r_go_relaxed.owl	4-(hydroxymethyl)benzenesulfonate:NAD+ oxidoreductase activity|4-(hydroxymethyl)benzenesulphonate dehydrogenase activity|4-sulfobenzyl alcohol dehydrogenase activity				KEGG_REACTION:R05271|RHEA:24412|UM-BBD_reactionID:r0291|MetaCyc:1.1.1.257-RXN|EC:1.1.1.257									molecular_function											owl:Class	
GO:0034677	biolink:NamedThing	integrin alpha7-beta1 complex	An integrin complex that comprises one alpha7 subunit and one beta1 subunit.	tmpzr1t_l9r_go_relaxed.owl	alpha7-beta1 integrin complex|ITGA7-ITGB1 complex													cellular_component											owl:Class	
GO:1900647	biolink:NamedThing	negative regulation of chanoclavine-I aldehyde biosynthetic process	Any process that stops, prevents or reduces the frequency, rate or extent of chanoclavine-I aldehyde biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	down regulation of chanoclavine-I aldehyde formation|downregulation of chanoclavine-I aldehyde formation|inhibition of chanoclavine-I aldehyde synthesis|inhibition of chanoclavine-I aldehyde biosynthesis|inhibition of chanoclavine-I aldehyde anabolism|downregulation of chanoclavine-I aldehyde biosynthetic process|down-regulation of chanoclavine-I aldehyde biosynthetic process|inhibition of chanoclavine-I aldehyde biosynthetic process|down regulation of chanoclavine-I aldehyde biosynthetic process|down-regulation of chanoclavine-I aldehyde formation|inhibition of chanoclavine-I aldehyde formation|negative regulation of chanoclavine-I aldehyde formation|negative regulation of chanoclavine-I aldehyde biosynthesis|downregulation of chanoclavine-I aldehyde anabolism|down regulation of chanoclavine-I aldehyde synthesis|downregulation of chanoclavine-I aldehyde synthesis|down regulation of chanoclavine-I aldehyde anabolism|negative regulation of chanoclavine-I aldehyde synthesis|down-regulation of chanoclavine-I aldehyde synthesis|down regulation of chanoclavine-I aldehyde biosynthesis|down-regulation of chanoclavine-I aldehyde anabolism|down-regulation of chanoclavine-I aldehyde biosynthesis|negative regulation of chanoclavine-I aldehyde anabolism|downregulation of chanoclavine-I aldehyde biosynthesis							di	2012-05-22T04:04:59Z					biological_process											owl:Class	
GO:0098768	biolink:NamedThing	meiotic prometaphase I	The meiotic cell cycle phase in eukaryotes between meiotic prophase I and meiotic metaphase I. During meiotic prometaphase I, the nuclear envelope breaks down and one kinetochore forms per chromosome. Chromosomes attach to spindle microtubules and begin to move towards the metaphase plate.	tmpzr1t_l9r_go_relaxed.owl						This term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation should be to 'regulation of x/y phase transition' or to a process which occurs during the reported phase (e.g. mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).								biological_process											owl:Class	
GO:0070581	biolink:NamedThing	rolling circle DNA replication	A DNA-dependent DNA replication process in which a single-stranded DNA molecule is synthesized from a circular duplex template. Replication typically does not cease when one circumference has been replicated, but continues around the circumference several more times, producing a long single strand comprising multimers of the replicon.	tmpzr1t_l9r_go_relaxed.owl	rolling circle replication							mah	2009-04-22T02:53:52Z					biological_process											owl:Class	
GO:0009432	biolink:NamedThing	SOS response	An error-prone process for repairing damaged microbial DNA.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:SOS_response									biological_process											owl:Class	
GO:0015155	biolink:NamedThing	lactose transmembrane transporter activity	Enables the transfer of lactose from one side of a membrane to the other. Lactose is a disaccharide 4-O-beta-D-galactopyranosyl-D-glucose, and constitutes roughly 5% of the milk in almost all mammals.	tmpzr1t_l9r_go_relaxed.owl	lactose/glucose efflux transporter activity|lactose permease activity											GO:0019189		molecular_function											owl:Class	
GO:0018763	biolink:NamedThing	hydroxydechloroatrazine ethylaminohydrolase activity	Catalysis of the reaction: 4-(ethylamino)-2-hydroxy-6-(isopropylamino)-1,3,5-triazine + H2O = N-isopropylammelide + ethylamine.	tmpzr1t_l9r_go_relaxed.owl	hydroxyatrazine ethylaminohydrolase activity|AtzB|4-(ethylamino)-2-hydroxy-6-(isopropylamino)-1,3,5-triazine ethylaminohydrolase activity|hydroxyatrazine hydrolase activity				RHEA:23092|UM-BBD_enzymeID:e0085|EC:3.5.4.43|MetaCyc:R122-RXN									molecular_function											owl:Class	
GO:0006847	biolink:NamedThing	plasma membrane acetate transport	The directed movement of acetate across a plasma membrane.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0031530	biolink:NamedThing	gonadotropin-releasing hormone receptor binding	Binding to a receptor for gonadotropin-releasing hormone (GnRH), a peptide hormone that is synthesized and released by the hypothalamus and is responsible for the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) from the anterior pituitary.	tmpzr1t_l9r_go_relaxed.owl	GnRH receptor binding|gonadotrophin-releasing hormone receptor binding													molecular_function											owl:Class	
GO:0050100	biolink:NamedThing	methylitaconate delta-isomerase activity	Catalysis of the reaction: 2-methylene-3-methylsuccinate = dimethylmaleate.	tmpzr1t_l9r_go_relaxed.owl	methylitaconate D-isomerase activity|methylitaconate isomerase activity|methylitaconate delta2-delta3-isomerase activity				MetaCyc:METHYLITACONATE-DELTA-ISOMERASE-RXN|EC:5.3.3.6|RHEA:23480|KEGG_REACTION:R03070									molecular_function											owl:Class	
GO:0098757	biolink:NamedThing	cellular response to interleukin-21	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-21 stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to IL-21													biological_process											owl:Class	
GO:0098756	biolink:NamedThing	response to interleukin-21	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-21 stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to IL-21													biological_process											owl:Class	
GO:1990038	biolink:NamedThing	Lewy body corona	The periphery of a Lewy body. In Parkinson's disease, it contains spherical accumulations of filaments arranged in a loose, radiating array.	tmpzr1t_l9r_go_relaxed.owl	halo				NIF_Subcellular:sao5764355747			pr	2013-02-08T13:03:27Z					cellular_component											owl:Class	
GO:0048535	biolink:NamedThing	lymph node development	The process whose specific outcome is the progression of lymph nodes over time, from their formation to the mature structure. A lymph node is a round, oval, or bean shaped structure localized in clusters along the lymphatic vessels, with a distinct internal structure including specialized vasculature and B- and T-zones for the activation of lymphocytes.	tmpzr1t_l9r_go_relaxed.owl	lymph gland development													biological_process											owl:Class	
GO:0120043	biolink:NamedThing	stereocilium shaft	The shaft comprises the majority of the length of the stereocilium. This region is notable for the extreme stability of actin filaments, which are highly crosslinked into a parallel bundle.	tmpzr1t_l9r_go_relaxed.owl								krc	2017-05-15T20:38:32Z					cellular_component											owl:Class	
GO:0050144	biolink:NamedThing	nucleoside deoxyribosyltransferase activity	Catalysis of the reaction: 2-deoxy-D-ribosyl-base1 + base2 = 2-deoxy-D-ribosyl-base2 + base1.	tmpzr1t_l9r_go_relaxed.owl	nucleoside deoxyribosyltransferase II [purine(pyrimidine) nucleoside:purine(pyrimidine) deoxyribosyltransferase]|purine(pyrimidine) nucleoside:purine(pyrimidine) deoxyribosyl transferase activity|trans-deoxyribosylase activity|nucleoside trans-N-deoxyribosylase activity|nucleoside:purine(pyrimidine) deoxy-D-ribosyltransferase activity|nucleoside deoxyribosyltransferase I (purine nucleoside:purine deoxyribosyltransferase: strictly specific for transfer between purine bases)|deoxyribose transferase activity|trans-N-deoxyribosylase activity|trans-N-glycosidase activity				MetaCyc:NUCLEOSIDE-DEOXYRIBOSYLTRANSFERASE-RXN|EC:2.4.2.6									molecular_function											owl:Class	
GO:0050039	biolink:NamedThing	lactaldehyde reductase (NADPH) activity	Catalysis of the reaction: NADP(+) + propane-1,2-diol = (S)-lactaldehyde + H(+) + NADPH.	tmpzr1t_l9r_go_relaxed.owl	1,2-propanediol:NADP+ oxidoreductase activity|propanediol dehydrogenase activity|propane-1,2-diol:NADP+ oxidoreductase activity|lactaldehyde (reduced nicotinamide adenine dinucleotide phosphate) reductase activity|NADP-1,2-propanediol dehydrogenase activity				EC:1.1.1.55|MetaCyc:LACTALDEHYDE-REDUCTASE-NADPH-RXN|KEGG_REACTION:R02259|RHEA:15885									molecular_function											owl:Class	
GO:0018269	biolink:NamedThing	GPI anchor biosynthetic process via N-seryl-glycosylphosphatidylinositolethanolamine	The chemical reactions and pathways resulting in the formation of a C-terminal peptidyl-serine ethanolamide-linked glycosylphosphatidylinositol (GPI) anchor following hydrolysis of a seryl-peptide bond in the carboxy-terminal region of a membrane-associated protein.	tmpzr1t_l9r_go_relaxed.owl	GPI anchor anabolism via N-seryl-glycosylphosphatidylinositolethanolamine|GPI anchor synthesis via N-seryl-glycosylphosphatidylinositolethanolamine|GPI anchor formation via N-seryl-glycosylphosphatidylinositolethanolamine				RESID:AA0162									biological_process											owl:Class	
GO:1901883	biolink:NamedThing	4-hydroxycoumarin catabolic process	The chemical reactions and pathways resulting in the breakdown of 4-hydroxycoumarin.	tmpzr1t_l9r_go_relaxed.owl	4-hydroxycoumarin catabolism|4-hydroxycoumarin degradation|4-hydroxycoumarin breakdown							ms	2013-02-06T14:05:54Z					biological_process											owl:Class	
GO:0048478	biolink:NamedThing	replication fork protection	Any process that prevents the collapse of stalled replication forks.	tmpzr1t_l9r_go_relaxed.owl	replication fork maintenance|replication fork stabilization													biological_process											owl:Class	
GO:0046875	biolink:NamedThing	ephrin receptor binding	Binding to an ephrin receptor.	tmpzr1t_l9r_go_relaxed.owl	GPI-linked ephrin|transmembrane ephrin|Eph receptor binding|ephrin													molecular_function											owl:Class	
GO:0071205	biolink:NamedThing	protein localization to juxtaparanode region of axon	Any process in which a protein is transported to, or maintained at, the juxtaparanode region of an axon.	tmpzr1t_l9r_go_relaxed.owl	protein localisation to juxtaparanode region of axon							mah	2009-11-25T01:13:55Z					biological_process											owl:Class	
GO:0000016	biolink:NamedThing	lactase activity	Catalysis of the reaction: lactose + H2O = D-glucose + D-galactose.	tmpzr1t_l9r_go_relaxed.owl	lactase-phlorizin hydrolase activity|lactose galactohydrolase activity				EC:3.2.1.108|Reactome:R-HSA-5658001|Reactome:R-HSA-189062|MetaCyc:LACTASE-RXN|RHEA:10076									molecular_function											owl:Class	
GO:0060230	biolink:NamedThing	lipoprotein lipase activator activity	Binds to and increases the activity of a lipoprotein lipase, an enzyme that catalyzes of the hydrolysis of a lipid within a lipoprotein.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0034199	biolink:NamedThing	activation of protein kinase A activity	Any process that initiates the activity of the inactive enzyme protein kinase A.	tmpzr1t_l9r_go_relaxed.owl	protein kinase A activation													biological_process											owl:Class	
GO:0051777	biolink:NamedThing	ent-kaurenoate oxidase activity	Catalysis of the reaction: ent-kaurenoate + NADPH + O2 = ent-7-alpha-hydroxykaurenoate + NADP+ + H2O. This is the first of three successive reactions resulting in the oxidation of ent-kaurenoate (ent-kaurenoic acid) to gibberellin 12 (GA12).	tmpzr1t_l9r_go_relaxed.owl	ent-kaurenoic acid oxidase activity|ent-kaur-16-en-19-oate,NADPH:oxygen oxidoreductase (hydroxylating) activity				MetaCyc:1.14.13.79-RXN|RHEA:19241	Note that the enzyme ent-kaurenoate oxidase also catalyzes the reactions represented by the molecular function terms 'ent-7-alpha-hydroxykaurenoate oxidase activity ; GO:0051778' and 'gibberellin 12-aldehyde oxidase activity ; GO:0051779'.								molecular_function											owl:Class	
GO:1900703	biolink:NamedThing	positive regulation of orcinol biosynthetic process	Any process that activates or increases the frequency, rate or extent of orcinol biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of orcinol anabolism|up-regulation of orcinol anabolism|up regulation of orcinol biosynthetic process|up-regulation of orcinol synthesis|up-regulation of orcinol formation|activation of orcinol biosynthesis|positive regulation of orcinol synthesis|upregulation of orcinol biosynthesis|up regulation of orcinol formation|up regulation of orcinol synthesis|up regulation of orcinol biosynthesis|up-regulation of orcinol biosynthesis|up-regulation of orcinol biosynthetic process|positive regulation of orcinol biosynthesis|upregulation of orcinol synthesis|activation of orcinol anabolism|upregulation of orcinol biosynthetic process|positive regulation of orcinol formation|activation of orcinol biosynthetic process|activation of orcinol formation|up regulation of orcinol anabolism|upregulation of orcinol formation|upregulation of orcinol anabolism|activation of orcinol synthesis							di	2012-05-22T04:58:28Z					biological_process											owl:Class	
GO:0140262	biolink:NamedThing	mRNA cap binding complex binding	Binding to a mRNA cap binding complex.	tmpzr1t_l9r_go_relaxed.owl								pg	2018-09-12T12:56:16Z					molecular_function											owl:Class	
GO:0099180	biolink:NamedThing	zinc ion import into synaptic vesicle	The directed movement of Zn2+ ions from the cytoplasm into the lumen of a cytoplasmic vesicle.	tmpzr1t_l9r_go_relaxed.owl	Zn2+ import into synaptic vesicle|zinc import into synaptic vesicle													biological_process											owl:Class	
GO:0018165	biolink:NamedThing	peptidyl-tyrosine uridylylation	The uridylylation of peptidyl-tyrosine to form peptidyl-O4'-(phospho-5'-uridine)-L-tyrosine, found in glutamine synthetase.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0256									biological_process											owl:Class	
GO:0030098	biolink:NamedThing	lymphocyte differentiation	The process in which a relatively unspecialized precursor cell acquires specialized features of a lymphocyte. A lymphocyte is a leukocyte commonly found in the blood and lymph that has the characteristics of a large nucleus, a neutral staining cytoplasm, and prominent heterochromatin.	tmpzr1t_l9r_go_relaxed.owl	lymphocyte cell differentiation|lymphocytic blood cell differentiation|lymphocyte development					Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.						GO:0046650		biological_process											owl:Class	
GO:0010024	biolink:NamedThing	phytochromobilin biosynthetic process	The chemical reactions and pathways resulting in the formation of phytochromobilin, which involves the oxidative cleavage of heme by a heme oxygenase(HO) to form biliverdin IX alpha.	tmpzr1t_l9r_go_relaxed.owl	phytochromobilin synthesis|phytochromobilin anabolism|phytochromobilin formation|phytochromobilin biosynthesis													biological_process											owl:Class	
GO:2001299	biolink:NamedThing	N(omega),N(omega)-dimethyl-L-arginine catabolic process	The chemical reactions and pathways resulting in the breakdown of N(omega),N(omega)-dimethyl-L-arginine, a methyl-L-arginine having two methyl groups both attached to the primary amino moiety of the guanidino group.	tmpzr1t_l9r_go_relaxed.owl	N(omega),N(omega)-dimethyl-L-arginine catabolism|N(omega),N(omega)-dimethyl-L-arginine breakdown|N(omega),N(omega)-dimethyl-L-arginine degradation							pr	2012-02-14T03:40:03Z					biological_process											owl:Class	
GO:0036204	biolink:NamedThing	abieta-7,13-dien-18-ol hydroxylase activity	Catalysis of the reaction: abieta-7,13-dien-18-ol + NADPH + H+ + O2 = abieta-7,13-dien-18-al + NADP+ + 2 H2O. This is a two step reaction. The first step is: abieta-7,13-dien-18-ol + NADPH + H+ + O2 = abieta-7,13-dien-18,18-diol + + NADP+ + H2O. The second step is a spontaneous reaction: abieta-7,13-dien-18,18-diol = abieta-7,13-dien-18-al + H2O.	tmpzr1t_l9r_go_relaxed.owl					KEGG_REACTION:R06354|EC:1.14.14.145|MetaCyc:RXN-12799|RHEA:26221			bf	2012-04-24T02:37:15Z					molecular_function											owl:Class	
GO:0052691	biolink:NamedThing	UDP-arabinopyranose mutase activity	Catalysis of the reaction: UDP-beta-L-arabinofuranose = UDP-beta-L-arabinopyranose.	tmpzr1t_l9r_go_relaxed.owl	UDP-L-Ara mutase activity|UDP-L-arabinose mutase activity|uridine-diphosphate-L-arabinose mutase activity|UDP-L-arabinopyranose furanomutase activity|UDP-arabinopyranose pyranomutase activity				RHEA:28350|EC:5.4.99.30|MetaCyc:RXN-11552									molecular_function											owl:Class	
GO:0046424	biolink:NamedThing	ferulate 5-hydroxylase activity	Catalysis of the reaction: ferulic acid + NADPH + H+ + O2 = 5-hydroxyferulic acid + H2O + NADP+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-1121									molecular_function											owl:Class	
GO:0006062	biolink:NamedThing	sorbitol catabolic process	The chemical reactions and pathways resulting in the breakdown of sorbitol (D-glucitol), one of the ten stereoisomeric hexitols. It can be derived from glucose by reduction of the aldehyde group.	tmpzr1t_l9r_go_relaxed.owl	sorbitol degradation|sorbitol catabolism|sorbitol breakdown				MetaCyc:SORBDEG-PWY									biological_process											owl:Class	
GO:0071756	biolink:NamedThing	pentameric IgM immunoglobulin complex	A circulating form of IgM consisting of a pentamer of IgM core units with a single J chain polypeptide.	tmpzr1t_l9r_go_relaxed.owl	pentameric IgM antibody					Note that an IgM immunoglobulin complex has the function of antigen binding if a suitable antigen is available.		mah	2010-03-24T01:44:53Z					cellular_component											owl:Class	
GO:0102899	biolink:NamedThing	dehydroabietadienol hydroxylase activity	Catalysis of the reaction: H+ + dehydroabietadienol + NADPH + O2 <=> dehydroabietadiene-diol + NADP + H2O.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-8532									molecular_function											owl:Class	
GO:0015309	biolink:NamedThing	cycloheximide:proton antiporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + cycloheximide(in) = H+(in) + cycloheximide(out).	tmpzr1t_l9r_go_relaxed.owl	cycloheximide:hydrogen antiporter activity													molecular_function											owl:Class	
GO:0032015	biolink:NamedThing	regulation of Ran protein signal transduction	Any process that modulates the frequency, rate or extent of Ran protein signal transduction.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0060459	biolink:NamedThing	left lung development	The biological process whose specific outcome is the progression of a left lung from an initial condition to its mature state. This process begins with the formation of the left lung and ends with the mature structure. The left lung is the lung which is on the left side of the anterior posterior axis looking from a dorsal to ventral aspect.	tmpzr1t_l9r_go_relaxed.owl	left pulmonary development													biological_process											owl:Class	
GO:0019916	biolink:NamedThing	peptidyl-D-alanine racemization, direct	The racemization of peptidyl-alanine.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0191									biological_process											owl:Class	
GO:0043573	biolink:NamedThing	leucoplast fission	The creation of two or more leucoplasts by division of one leucoplast. A leucoplast is a colorless plastid involved in the synthesis of monoterpenes.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0003842	biolink:NamedThing	1-pyrroline-5-carboxylate dehydrogenase activity	Catalysis of the reaction: 1-pyrroline-5-carboxylate + NAD+ + H2O = L-glutamate + NADH + H(+).	tmpzr1t_l9r_go_relaxed.owl	delta1-pyrroline-5-carboxylate dehydrogenase activity|L-pyrroline-5-carboxylate-NAD+ oxidoreductase activity|pyrroline-5-carboxylate dehydrogenase activity|pyrroline-5-carboxylic acid dehydrogenase activity|1-pyrroline-5-carboxylate:NAD+ oxidoreductase activity|1-pyrroline dehydrogenase				RHEA:16417|MetaCyc:PYRROLINECARBDEHYDROG-RXN|Reactome:R-HSA-6784399|EC:1.2.1.88|Reactome:R-HSA-70679									molecular_function											owl:Class	
GO:2001125	biolink:NamedThing	negative regulation of translational frameshifting	Any process that stops, prevents or reduces the frequency, rate or extent of translational frameshifting.	tmpzr1t_l9r_go_relaxed.owl								dph	2011-10-12T05:52:27Z					biological_process											owl:Class	
GO:0014719	biolink:NamedThing	skeletal muscle satellite cell activation	The change of a skeletal muscle satellite cell from a mitotically quiescent to a mitotically active state following exposure to some activating factor  such as a cellular or soluble ligand. In adult muscle, satellite cells become activated to divide and differentiate in response to muscle damage.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0102320	biolink:NamedThing	1,8-cineole 2-exo-monooxygenase activity	Catalysis of the reaction: 1,8-cineole + NADPH + H+ + O2 <=> 2-exo-hydroxy-1,8-cineole + NADP + H2O.	tmpzr1t_l9r_go_relaxed.owl					RHEA:32895|MetaCyc:RXN-13133|EC:1.14.14.56									molecular_function											owl:Class	
GO:0090443	biolink:NamedThing	FAR/SIN/STRIPAK complex	A conserved protein phosphatase type 2A complex which contains a protein phosphatase type 2A, a protein phosphatase regulatory subunit, a striatin, an FHA domain protein and other subunits (at least six proteins). In fission yeast this complex negatively regulate the septation initiation network at the spindle pole body.	tmpzr1t_l9r_go_relaxed.owl	FAR complex|SIP complex|STRIPAK signalling complex|striatin interacting phosphatase and kinase complex							tb	2012-08-23T14:20:39Z					cellular_component											owl:Class	
GO:0035900	biolink:NamedThing	response to isolation stress	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lack of contact with other members of the same species.	tmpzr1t_l9r_go_relaxed.owl	response to social isolation							bf	2011-06-22T09:39:57Z					biological_process											owl:Class	
GO:0031425	biolink:NamedThing	chloroplast RNA processing	The conversion of a primary RNA molecule transcribed from a chloroplast genome into one or more mature RNA molecules.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0035316	biolink:NamedThing	non-sensory hair organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of non-sensory hairs. These hairs are polarized cellular extensions that cover much of the insect epidermis.	tmpzr1t_l9r_go_relaxed.owl	non-sensory hair organization and biogenesis|trichome organization and biogenesis|trichome organisation					See also the fly_anatomy.ontology term 'trichome ; FBbt:00004979'.								biological_process											owl:Class	
GO:0018391	biolink:NamedThing	C-terminal peptidyl-glutamic acid tyrosinylation	The ATP-dependent addition of a tyrosine residue to a glutamic acid residue at the C-terminus of a protein.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0017195	biolink:NamedThing	N-terminal peptidyl-lysine N2-acetylation	The acetylation of the N-terminal lysine of proteins to form the derivative N2-acetyl-L-lysine. The occurrence of this modification has not been confirmed.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0048									biological_process											owl:Class	
GO:0102103	biolink:NamedThing	demethoxycurcumin synthase	Catalysis of the reaction: (4-coumaroyl)acetyl-CoA + 4-coumaryl-CoA + H2O <=> bisdemethoxycurcumin + 2 coenzyme A + carbon dioxide.	tmpzr1t_l9r_go_relaxed.owl					RHEA:35119|MetaCyc:RXN-11223|EC:2.3.1.219									molecular_function											owl:Class	
GO:0062032	biolink:NamedThing	cichorine biosynthetic process	The chemical reactions and pathways resulting in the formation of cichorine, a secondary metabolite found in some species of fungi.	tmpzr1t_l9r_go_relaxed.owl	cichorine formation|cichorine synthesis|cichorine anabolism|cichorine biosynthesis							dph	2018-04-19T16:22:09Z					biological_process											owl:Class	
GO:0102697	biolink:NamedThing	trans-zeatin-O-glucoside UDP glycosyltransferase activity	Catalysis of the reaction: UDP-alpha-D-glucose + O-beta-D-glucosyl-trans-zeatin = H+ + trans-zeatin-O-glucoside-7-N-glucoside + UDP.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-4736									molecular_function											owl:Class	
GO:0046553	biolink:NamedThing	D-malate dehydrogenase (decarboxylating) activity	Catalysis of the reaction: (R)-malate + NAD(+) = CO(2) + NADH + pyruvate.	tmpzr1t_l9r_go_relaxed.owl	bifunctional L(+)-tartrate dehydrogenase-D(+)-malate (decarboxylating)|(R)-malate:NAD+ oxidoreductase (decarboxylating)|D-malic enzyme|D-malate dehydrogenase activity				KEGG_REACTION:R00215|EC:1.1.1.83|RHEA:18365|MetaCyc:1.1.1.83-RXN									molecular_function											owl:Class	
GO:0005832	biolink:NamedThing	chaperonin-containing T-complex	A multisubunit ring-shaped complex that mediates protein folding in the cytosol without a cofactor.	tmpzr1t_l9r_go_relaxed.owl	CCT particle|TriC													cellular_component											owl:Class	
GO:0090590	biolink:NamedThing	protein-N(PI)-phosphohistidine-D-glucosamine phosphotransferase system transporter activity	Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + D-glucosamine(out) = protein histidine + glucosamine-6-phosphate(in).	tmpzr1t_l9r_go_relaxed.owl								tb	2014-06-04T16:33:01Z					molecular_function											owl:Class	
GO:0140541	biolink:NamedThing	piRNA transcription	The cellular synthesis of Piwi-interacting RNA piRNAs, a class of 24- to 30-nucleotide RNA derived from repeat or complex DNA sequence elements and processed by a Dicer-independent mechanism.	tmpzr1t_l9r_go_relaxed.owl	Piwi-associated RNA transcription|PIWI-interacting RNA transcription	https://github.com/geneontology/go-ontology/issues/19530						pg	2020-11-09T16:53:25Z					biological_process											owl:Class	
GO:0018938	biolink:NamedThing	2-nitropropane metabolic process	The chemical reactions and pathways involving 2-nitropropane, a clear, colorless liquid with a mild, fruity odor. 2-nitropropane is used principally as a solvent and chemical intermediate. As a solvent, it is used in inks, paints, adhesives, varnishes, polymers, and synthetic materials. It is a feedstock for the manufacture of 2-nitro-2-methyl-1-propanol and 2-amino-2-methyl-1-propanol.	tmpzr1t_l9r_go_relaxed.owl	2-nitropropane metabolism				MetaCyc:PWY-723|UM-BBD_pathwayID:npp									biological_process											owl:Class	
GO:1900447	biolink:NamedThing	regulation of cell morphogenesis involved in phenotypic switching	Any process that modulates the frequency, rate or extent of cell morphogenesis contributing a phenotypic switch. Cell morphogenesis involved in differentiation is the change in form (cell shape and size) that occurs when relatively unspecialized cells, such as the opaque cells of C. albicans, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of cell shape and cell size of phenotypic dimorphism|negative regulation of cell shape and cell size of phenotypic dimorphism|regulation of cell morphogenesis of phenotypic dimorphism|regulation of cell shape and cell size of phenotypic dimorphism|negative regulation of cell shape and cell size of phenotypic switching|regulation of cell morphogenesis of phenotypic switching|regulation of cell shape and cell size of phenotypic switching|positive regulation of cell shape and cell size of phenotypic switching							di	2012-04-27T02:43:32Z					biological_process											owl:Class	
GO:0120310	biolink:NamedThing	amastigogenesis	The morphological, biochemical and genetic changes that induce the differentiation of metacyclic parasites into amastigotes in some of the Trypanosomatidae species such as Leishmania parasites and Trypanosoma cruzi. This process occurs inside the cells of the mammalian hosts, particularly in macrophages and other phagocytic cells for Leishmania parasites.	tmpzr1t_l9r_go_relaxed.owl								krc	2021-03-23T21:17:19Z					biological_process											owl:Class	
GO:1904349	biolink:NamedThing	positive regulation of small intestine smooth muscle contraction	Any process that activates or increases the frequency, rate or extent of small intestine smooth muscle contraction.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of small intestine smooth muscle contraction|up regulation of small intestine smooth muscle contraction|activation of small intestine smooth muscle contraction|upregulation of small intestine smooth muscle contraction							sl	2015-06-11T21:37:46Z					biological_process											owl:Class	
GO:1902858	biolink:NamedThing	propionyl-CoA metabolic process	The chemical reactions and pathways involving propionyl-CoA.	tmpzr1t_l9r_go_relaxed.owl	propionyl-CoA metabolism							tt	2014-04-03T03:10:17Z					biological_process											owl:Class	
GO:1902330	biolink:NamedThing	synthesis of RNA primer involved in bacterial-type DNA replication	Any synthesis of RNA primer that is involved in bacterial-type DNA replication.	tmpzr1t_l9r_go_relaxed.owl	replication priming involved in bacterial-type DNA replication							jl	2013-07-25T10:48:18Z					biological_process											owl:Class	
GO:0046762	biolink:NamedThing	viral budding from endoplasmic reticulum membrane	A viral budding that starts with formation of a membrane curvature in the host ER membrane.	tmpzr1t_l9r_go_relaxed.owl	viral budding from ER membrane|virus budding from ER membrane|ER membrane viral budding|endoplasmic reticulum membrane viral budding|virus budding from ER membrane during viral capsid envelopment|viral budding from ER membrane by viral capsid envelopment|ER membrane viral budding during viral capsid envelopment|viral budding from ER membrane during viral capsid envelopment|endoplasmic reticulum membrane viral budding during viral capsid envelopment|virus budding from ER membrane by viral capsid envelopment											GO:0046751|GO:0046764		biological_process											owl:Class	
GO:0071095	biolink:NamedThing	alpha3-beta1 integrin-thrombospondin complex	A protein complex that consists of an alpha3-beta1 integrin complex bound to thrombospondin.	tmpzr1t_l9r_go_relaxed.owl	ITGA3-ITGB1-THBS1 complex							mah	2009-11-06T04:48:03Z					cellular_component											owl:Class	
GO:0033409	biolink:NamedThing	UAU codon-amino acid adaptor activity	A triplet codon-amino acid adaptor activity that recognizes a UAU codon.	tmpzr1t_l9r_go_relaxed.owl	tyrosine tRNA|TAT codon-amino acid adaptor activity					Note that in the standard genetic code, TAT codes for tyrosine.								molecular_function											owl:Class	
GO:1905353	biolink:NamedThing	ciliary transition fiber assembly	The aggregation, arrangement and bonding together of a set of components to form a ciliary transition fiber.	tmpzr1t_l9r_go_relaxed.owl	distal appendage of mother centriole formation|cilial transition fibre formation|cilial transition fiber formation|centriolar distal appendage assembly|distal appendage of basal body assembly|cilial transition fiber assembly|cilium transition fiber formation|centriolar distal appendage formation|ciliary transition fiber formation|distal appendage of mother centriole assembly|cilium transition fibre formation|distal appendage of centriole assembly|ciliary transition fibre assembly|cilium transition fiber assembly|ciliary transition fibre formation|cilium transition fibre assembly|cilial transition fibre assembly|distal appendage of basal body formation|distal appendage of centriole formation							pr	2016-08-05T14:01:32Z					biological_process											owl:Class	
GO:0000131	biolink:NamedThing	incipient cellular bud site	The portion of the budding yeast plasma membrane where a daughter cell will emerge. The yeast marks this spot with bud-site selection proteins before bud emergence occurs. Actin is polarized to this spot just prior to and during bud emergence.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0072259	biolink:NamedThing	metanephric interstitial fibroblast development	The process whose specific outcome is the progression of a metanephric interstitial fibroblast over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl	metanephros interstitial cell development							mah	2010-03-19T04:18:00Z					biological_process											owl:Class	
GO:0051064	biolink:NamedThing	TTP reductase activity	Catalysis of the reaction: dTTP + thioredoxin disulfide + H2O = TTP + thioredoxin. Thioredoxin disulfide is the oxidized form of thioredoxin.	tmpzr1t_l9r_go_relaxed.owl	TTP reduction				EC:1.17.4.-									molecular_function											owl:Class	
GO:0030283	biolink:NamedThing	testosterone dehydrogenase [NAD(P)] activity	Catalysis of the reaction: testosterone + NAD(P)+ = androst-4-ene-3,17-dione + NAD(P)H + H+.	tmpzr1t_l9r_go_relaxed.owl	3beta-hydroxysteroid dehydrogenase|3beta-hydroxy steroid dehydrogenase|17beta-hydroxy steroid dehydrogenase|3(or 17)beta-hydroxysteroid dehydrogenase activity|beta-hydroxy steroid dehydrogenase|3(or 17)beta-hydroxysteroid:NAD(P)+ oxidoreductase				EC:1.1.1.51|MetaCyc:1.1.1.51-RXN|Reactome:R-HSA-193064									molecular_function											owl:Class	
GO:0098615	biolink:NamedThing	dimethyl selenide methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + dimethyl selenide => S-adenosyl-L-homocysteine + trimethylselenonium.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-2408554									molecular_function											owl:Class	
GO:0034793	biolink:NamedThing	cyclopropanecarboxylate-CoA ligase activity	Catalysis of the reaction: cyclopropanecarboxylate + CoASH = cyclopropanecarboxyl-CoA + OH-.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r1056									molecular_function											owl:Class	
GO:2000070	biolink:NamedThing	regulation of response to water deprivation	Any process that modulates the frequency, rate or extent of response to water deprivation.	tmpzr1t_l9r_go_relaxed.owl	regulation of drought tolerance|regulation of response to dehydration|regulation of response to thirst|regulation of response to drought							tb	2010-08-23T11:32:32Z					biological_process											owl:Class	
GO:0036447	biolink:NamedThing	cellular response to sugar-phosphate stress	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the accumulation of sugar-phosphate.	tmpzr1t_l9r_go_relaxed.owl	cellular response to presence of non-metabolizable sugars							bf	2013-10-31T11:18:09Z					biological_process											owl:Class	
GO:0061707	biolink:NamedThing	extracellular exosome macropinocytosis	The single-organism macropinocytosis process that results in the uptake of an extracellular exosome.	tmpzr1t_l9r_go_relaxed.owl								dph	2015-06-15T16:02:38Z					biological_process											owl:Class	
GO:0019922	biolink:NamedThing	protein-chromophore linkage via peptidyl-cysteine	The covalent linking of a chromophore to a protein via peptidyl-cysteines.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0043807	biolink:NamedThing	3-methyl-2-oxobutanoate dehydrogenase (ferredoxin) activity	Catalysis of the reaction: 3-methyl-2-oxobutanoate + CoA + oxidized ferredoxin = S-(2-methylpropanoyl)-CoA + CO2 + reduced ferredoxin.	tmpzr1t_l9r_go_relaxed.owl	ketoisovalerate ferredoxin reductase activity|3-methyl-2-oxobutanoate synthase (ferredoxin) activity|branched-chain oxo acid ferredoxin reductase activity|keto-valine-ferredoxin oxidoreductase activity|3-methyl-2-oxobutanoate:ferredoxin oxidoreductase (decarboxylating; CoA-2-methylpropanoylating)|ketoisovalerate oxidoreductase activity|branched-chain ketoacid ferredoxin reductase activity|2-oxoisovalerate ferredoxin reductase activity|VOR|2-ketoisovalerate ferredoxin reductase activity				RHEA:11712|EC:1.2.7.7|MetaCyc:1.2.7.7-RXN									molecular_function											owl:Class	
GO:0120320	biolink:NamedThing	lateral pseudopodium retraction	The myosin-based contraction and retraction of a lateral pseudopodium.	tmpzr1t_l9r_go_relaxed.owl	lateral pseudopodium suppression							krc	2021-06-23T21:50:09Z					biological_process											owl:Class	
GO:0016507	biolink:NamedThing	mitochondrial fatty acid beta-oxidation multienzyme complex	A complex that includes the long-chain 3-hydroxyacyl-CoA dehydrogenase and long-chain enoyl-CoA hydratase activities in two subunits (alpha and beta), catalyzing two steps of the fatty acid beta-oxidation cycle within the mitochondrial matrix.	tmpzr1t_l9r_go_relaxed.owl	trifunctional enzyme|fatty acid beta-oxidation multienzyme complex													cellular_component											owl:Class	
GO:0075032	biolink:NamedThing	negative regulation of formation of symbiont germ tube hook structure for appressorium development	Any process that stops, prevents, or reduces the frequency, rate or extent of symbiont germ tube hook structure formation.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of germ tube tip of symbiont on or near the exterior of host|negative regulation of formation of symbiont germ tube hook structure on or near host|negative regulation of symbiont germ tube hook structure formation on or near host													biological_process											owl:Class	
GO:0051281	biolink:NamedThing	positive regulation of release of sequestered calcium ion into cytosol	Any process that activates or increases the frequency, rate or extent of the release into the cytosolic compartment of calcium ions sequestered in the endoplasmic reticulum or mitochondria.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of calcium ion (Ca2+) mobilization|positive regulation of release of sequestered calcium ion into cytoplasm|positive regulation of cytosolic release of sequestered calcium ion (Ca2+)|positive regulation of calcium mobilization|activation of release of sequestered calcium ion into cytosol|positive regulation of release of stored calcium ion (Ca2+)|positive regulation of release of stored calcium ion (Ca2+) into cytoplasm|up regulation of release of sequestered calcium ion into cytosol|positive regulation of cytoplasmic release of sequestered calcium ion (Ca2+)|positive regulation of cytoplasmic release of stored calcium ion (Ca2+)|upregulation of release of sequestered calcium ion into cytosol|stimulation of release of sequestered calcium ion into cytosol|positive regulation of release of stored calcium ion (Ca2+) into cytosol|positive regulation of cytosolic release of stored calcium ion (Ca2+)|up-regulation of release of sequestered calcium ion into cytosol|positive regulation of release of sequestered calcium ion (Ca2+)													biological_process											owl:Class	
GO:0070662	biolink:NamedThing	mast cell proliferation	The expansion of a mast cell population by cell division.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-05-28T05:27:51Z					biological_process											owl:Class	
GO:0044418	biolink:NamedThing	translocation of DNA into host	The directed movement of DNA from an organism to a location inside its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	transport of DNA into other organism during symbiotic interaction|transport of DNA into host|translocation of DNA into other organism involved in symbiotic interaction|translocation of DNA into other organism during symbiotic interaction											GO:0051837		biological_process											owl:Class	
GO:0033854	biolink:NamedThing	glutamate-prephenate aminotransferase activity	Catalysis of the reaction: 2-oxoglutarate + L-arogenate = L-glutamate + prephenate.	tmpzr1t_l9r_go_relaxed.owl	L-arogenate:2-oxoglutarate aminotransferase activity|L-glutamate:prephenate aminotransferase activity|PAT|prephenate transaminase activity				RHEA:22880|MetaCyc:PREPHENATE-TRANSAMINE-RXN|KEGG_REACTION:R07276|EC:2.6.1.79									molecular_function											owl:Class	
GO:0042585	biolink:NamedThing	germinal vesicle	The enlarged, fluid filled nucleus of a primary oocyte, the development of which is suspended in prophase I of the first meiotic division between embryohood and sexual maturity.	tmpzr1t_l9r_go_relaxed.owl	primary oocyte nucleus													cellular_component											owl:Class	
GO:0001674	biolink:NamedThing	female germ cell nucleus	The nucleus of the female germ cell, a reproductive cell in females.	tmpzr1t_l9r_go_relaxed.owl	female germ-cell nucleus											GO:0043080		cellular_component											owl:Class	
GO:0008686	biolink:NamedThing	3,4-dihydroxy-2-butanone-4-phosphate synthase activity	Catalysis of the reaction: D-ribulose 5-phosphate = (2S)-2-hydroxy-3-oxobutyl phosphate + formate + H(+).	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:DIOHBUTANONEPSYN-RXN|RHEA:18457|EC:4.1.99.12|KEGG_REACTION:R07281									molecular_function											owl:Class	
GO:0097220	biolink:NamedThing	simple sieve plate	A sieve plate that contains a single specialized sieve area.	tmpzr1t_l9r_go_relaxed.owl						Often located on an end wall of a sieve tube member. Unspecialized sieve areas may occur on other parts of the cell.		pr	2012-01-13T05:46:46Z					cellular_component											owl:Class	
GO:0031171	biolink:NamedThing	ferricrocin biosynthetic process	The chemical reactions and pathways resulting in the formation of ferricrocin, a cyclic hexapeptide siderophore with the structure Gly-Ser-Gly-(N5-acetyl-N5-hydroxyornithine)3.	tmpzr1t_l9r_go_relaxed.owl	ferricrocin formation|ferricrocin synthesis|ferricrocin biosynthetic process, peptide modification|ferricrocin biosynthetic process, peptide formation|ferricrocin biosynthesis|ferricrocin anabolism											GO:0031185|GO:0031186		biological_process											owl:Class	
GO:0047863	biolink:NamedThing	dimethylallylcistransferase activity	Catalysis of the reaction: dimethylallyl diphosphate + isopentenyl diphosphate = diphosphate + neryl diphosphate.	tmpzr1t_l9r_go_relaxed.owl	neryl-diphosphate synthase activity|dimethylallyl-diphosphate:isopentenyl-diphosphate dimethylallylcistransferase activity				MetaCyc:DIMETHYLALLYLCISTRANSFERASE-RXN|EC:2.5.1.28|RHEA:11328|KEGG_REACTION:R01659									molecular_function											owl:Class	
GO:0050479	biolink:NamedThing	glyceryl-ether monooxygenase activity	Catalysis of the reaction: 1-alkyl-sn-glycerol + O2 + (tetrahydrobiopterin/tetrahydropteridine) = 1-hydroxyalkyl-sn-glycerol + H2O + (dihydrobiopterin/dihydropteridine).	tmpzr1t_l9r_go_relaxed.owl	glyceryl ether oxygenase activity|O-alkylglycerol monooxygenase activity|1-alkyl-sn-glycerol,tetrahydrobiopterin:oxygen oxidoreductase activity|glyceryl-ether cleaving enzyme activity|glyceryl etherase activity|alkylglycerol monooxygenase activity				Reactome:R-HSA-5696119|RHEA:36255|MetaCyc:GLYCERYL-ETHER-MONOOXYGENASE-RXN|EC:1.14.16.5									molecular_function											owl:Class	
GO:0070715	biolink:NamedThing	sodium-dependent organic cation transport	The directed, sodium-dependent, movement of organic cations into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-06-09T03:26:27Z					biological_process											owl:Class	
GO:0030598	biolink:NamedThing	rRNA N-glycosylase activity	Catalysis of the hydrolysis of the N-glycosylic bond at A-4324 in 28S rRNA from rat ribosomes or corresponding sites in 28S RNA from other species.	tmpzr1t_l9r_go_relaxed.owl	RNA N-glycosidase activity|gelonin|rRNA N-glycohydrolase activity|mirabilis antiviral protein|saporins|ribosomal ribonucleate N-glycosidase activity|rRNA N-glycosidase activity|ricin|nigrin b|momorcochin-S				MetaCyc:3.2.2.22-RXN|EC:3.2.2.22									molecular_function											owl:Class	
GO:0075028	biolink:NamedThing	negative regulation of appressorium initiation	Any process that stops, prevents, or reduces the frequency, rate or extent symbiont appressorium initiation.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of initiation of appressorium on or near host|negative regulation of appressorium initiation on or near host													biological_process											owl:Class	
GO:0047338	biolink:NamedThing	UTP:xylose-1-phosphate uridylyltransferase activity	Catalysis of the reaction: alpha-D-xylose 1-phosphate + UTP = UDP-D-xylose + diphosphate.	tmpzr1t_l9r_go_relaxed.owl	UDP-xylose pyrophosphorylase activity|UTP-xylose-1-phosphate uridylyltransferase activity|uridine diphosphoxylose pyrophosphorylase activity|UTP:alpha-D-xylose-1-phosphate uridylyltransferase activity|xylose 1-phosphate uridylyltransferase activity|xylose-1-phosphate uridylyltransferase activity|uridylyltransferase, xylose 1-phosphate				EC:2.7.7.11|MetaCyc:2.7.7.11-RXN|RHEA:18389									molecular_function											owl:Class	
GO:0043514	biolink:NamedThing	interleukin-12 complex	A protein complex that is composed of an interleukin-12 alpha (p35, product of the IL12A gene) and an interleukin-12 beta subunit (p40, product of the IL12B gene) and is secreted into the extracellular space.	tmpzr1t_l9r_go_relaxed.owl	p35|IL12B|IL12A|p40|IL-12 complex					Note that this heterodimeric cytokine utilizes the IL-12p35 subunit as its alpha chain, which is also used by IL-35 as its alpha chain, and utilizes the IL-12p40 subunit as its beta chain, which is also used by IL-23 as its beta chain.								cellular_component											owl:Class	
GO:1900875	biolink:NamedThing	heptadec-1-ene biosynthetic process	The chemical reactions and pathways resulting in the formation of heptadec-1-ene.	tmpzr1t_l9r_go_relaxed.owl	heptadec-1-ene synthesis|heptadec-1-ene formation|heptadec-1-ene biosynthesis|heptadec-1-ene anabolism							tt	2012-06-13T01:50:11Z					biological_process											owl:Class	
GO:1902000	biolink:NamedThing	homogentisate catabolic process	The chemical reactions and pathways resulting in the breakdown of homogentisate.	tmpzr1t_l9r_go_relaxed.owl	homogentisate degradation|homogentisate breakdown|homogentisate catabolism							tb	2013-03-21T00:01:12Z					biological_process											owl:Class	
GO:0047018	biolink:NamedThing	indole-3-acetaldehyde reductase (NADH) activity	Catalysis of the reaction: indole-3-ethanol + NAD(+) = (indol-3-yl)acetaldehyde + H(+) + NADH.	tmpzr1t_l9r_go_relaxed.owl	(indol-3-yl)ethanol:NAD+ oxidoreductase activity|indole-3-ethanol:NAD+ oxidoreductase activity|indoleacetaldehyde reductase activity				RHEA:14873|EC:1.1.1.190|KEGG_REACTION:R02679|MetaCyc:1.1.1.190-RXN									molecular_function											owl:Class	
GO:0090429	biolink:NamedThing	detection of endogenous biotic stimulus	The series of events in which an endogenous biotic stimulus is received by a cell and converted into a molecular signal.	tmpzr1t_l9r_go_relaxed.owl								tb	2012-05-11T09:19:39Z					biological_process											owl:Class	
GO:1990388	biolink:NamedThing	xylem-to-phloem iron transport	The directed movement of iron ions into the phloem from the xylem.	tmpzr1t_l9r_go_relaxed.owl								tb	2014-05-30T21:06:50Z					biological_process											owl:Class	
GO:0102639	biolink:NamedThing	paspalicine synthase activity	Catalysis of the reaction: 13-desoxypaxilline + NADPH + O2 + H+ <=> paspalicine + NADP + 2 H2O.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-15737									molecular_function											owl:Class	
GO:0140337	biolink:NamedThing	diacylglyceride transfer activity	Directly binding to diacylglyceride and delivering it either to an acceptor molecule or to a specific location.	tmpzr1t_l9r_go_relaxed.owl	diacylglyceride carrier activity							pg	2019-05-16T11:28:08Z					molecular_function											owl:Class	
GO:0004324	biolink:NamedThing	ferredoxin-NADP+ reductase activity	Catalysis of the reaction: reduced ferredoxin + NADP+ = oxidized ferredoxin + NADPH + H+.	tmpzr1t_l9r_go_relaxed.owl	NADPH:ferredoxin oxidoreductase activity|TPNH-ferredoxin reductase activity|NADP:ferredoxin oxidoreductase activity|ferredoxin-nicotinamide-adenine dinucleotide phosphate (oxidized) reductase activity|ferredoxin-TPN reductase activity|ferredoxin:NADP+ oxidoreductase activity|ferredoxin-NADP oxidoreductase activity|ferredoxin-nicotinamide adenine dinucleotide phosphate reductase activity|reduced nicotinamide adenine dinucleotide phosphate-adrenodoxin reductase activity|ferredoxin-NADP reductase activity|ferredoxin-NADP-oxidoreductase activity				EC:1.18.1.2|MetaCyc:1.18.1.2-RXN|RHEA:20125	Note that this term specifically refers to the reaction proceeding in the direction shown; it should therefore be used to annotate gene products that catalyze the oxidation of reduced ferredoxin or adrenodoxin; also consider annotating to the molecular function term 'NADPH-adrenodoxin reductase activity ; GO:0015039'.								molecular_function											owl:Class	
GO:0008937	biolink:NamedThing	ferredoxin-NAD(P) reductase activity	Catalysis of the reaction: reduced ferredoxin + NAD(P)+ = oxidized ferredoxin + NAD(P)H + H+.	tmpzr1t_l9r_go_relaxed.owl	ferredoxin reductase activity													molecular_function											owl:Class	
GO:0036355	biolink:NamedThing	2-iminoacetate synthase activity	Catalysis of the reaction: L-tyrosine + S-adenosyl-L-methionine + reduced acceptor = 2-iminoacetate + 4-methylphenol + 5'-deoxyadenosine + L-methionine + acceptor + 2 H+.	tmpzr1t_l9r_go_relaxed.owl					RHEA:26361|EC:4.1.99.19|MetaCyc:RXN-11319			bf	2012-09-19T14:52:51Z					molecular_function											owl:Class	
GO:0030020	biolink:NamedThing	extracellular matrix structural constituent conferring tensile strength	A constituent of the extracellular matrix that enables the matrix to resist longitudinal stress.	tmpzr1t_l9r_go_relaxed.owl	core matrisome|core extracellular matrix					Extracellular matrix collagen proteins may be annotated to this term. PMID:29632050, PMID:24443019								molecular_function											owl:Class	
GO:0097158	biolink:NamedThing	pre-mRNA intronic pyrimidine-rich binding	Binding to a pyrimidine-rich (CU-rich) intronic sequence of a pre-messenger RNA (pre-mRNA).	tmpzr1t_l9r_go_relaxed.owl	pre-messenger RNA intronic pyrimidine-rich binding							pr	2011-09-23T11:29:03Z					molecular_function											owl:Class	
GO:0097157	biolink:NamedThing	pre-mRNA intronic binding	Binding to an intronic sequence of a pre-messenger RNA (pre-mRNA).	tmpzr1t_l9r_go_relaxed.owl	pre-messenger RNA intronic binding							pr	2011-09-23T11:27:01Z					molecular_function											owl:Class	
GO:0043433	biolink:NamedThing	negative regulation of DNA-binding transcription factor activity	Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of a transcription factor, any factor involved in the initiation or regulation of transcription.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of DNA binding transcription factor activity|down regulation of transcription factor activity|downregulation of transcription factor activity|negative regulation of sequence-specific DNA binding transcription factor activity|negative regulation of androgen receptor activity|inhibition of transcription factor activity|down-regulation of transcription factor activity|negative regulation of transcription factor activity|negative regulation of thyroid hormone receptor activity								2011-07-15T10:56:12Z			GO:1904168|GO:2000824		biological_process											owl:Class	
GO:0046787	biolink:NamedThing	viral DNA repair	The process of restoring viral DNA after damage or errors in replication.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1904585	biolink:NamedThing	response to putrescine	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a putrescine stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to tetramethylenediamine|response to 1,4-Butanediamine|response to 1,4-Diaminobutane							sl	2015-08-20T14:35:39Z					biological_process											owl:Class	
GO:0008748	biolink:NamedThing	N-ethylmaleimide reductase activity	Catalysis of the reaction: N-ethylmaleimide + NADPH + 2 H+ = N-ethylsuccinimide + NADP+.	tmpzr1t_l9r_go_relaxed.owl					RHEA:35523|MetaCyc:RXN0-5101									molecular_function											owl:Class	
GO:0052608	biolink:NamedThing	echinenone 3-hydroxylase activity	Catalysis of the reaction: echinenone + a reduced electron acceptor + oxygen = 3-hydroxyechinenone + an oxidized electron acceptor + H2O.	tmpzr1t_l9r_go_relaxed.owl	beta-carotene hydroxylase activity|carotene beta-ring hydroxylase activity|beta-ring carotenoid 3-hydroxylase activity				MetaCyc:RXN-8214									molecular_function											owl:Class	
GO:0033421	biolink:NamedThing	CCU codon-amino acid adaptor activity	A triplet codon-amino acid adaptor activity that recognizes a CCU codon.	tmpzr1t_l9r_go_relaxed.owl	proline tRNA|CCT codon-amino acid adaptor activity					Note that in the standard genetic code, CCT codes for proline.								molecular_function											owl:Class	
GO:0047228	biolink:NamedThing	1,2-diacylglycerol 3-glucosyltransferase activity	Catalysis of the reaction: 1,2-diacylglycerol + UDP-D-glucose = 3-D-glucosyl-1,2-diacylglycerol + UDP.	tmpzr1t_l9r_go_relaxed.owl	UDPglucose:diacylglycerol glucosyltransferase activity|uridine diphosphoglucose-diacylglycerol glucosyltransferase activity|UDP-glucose:1,2-diacylglycerol glucosyltransferase activity|UDP-glucose:1,2-diacylglycerol 3-D-glucosyltransferase activity|UDPglucose:1,2-diacylglycerol 3-D-glucosyltransferase activity|UDP-glucose-diacylglycerol glucosyltransferase activity				EC:2.4.1.157|MetaCyc:2.4.1.157-RXN									molecular_function											owl:Class	
GO:1990962	biolink:NamedThing	xenobiotic transport across blood-brain barrier	The directed movement of a xenobiotic through the blood-brain barrier.	tmpzr1t_l9r_go_relaxed.owl	drug transport across blood-brain barrier							sl	2016-06-07T17:39:33Z					biological_process											owl:Class	
GO:0102287	biolink:NamedThing	4-coumaroylhexanoylmethane synthase activity	Catalysis of the reaction: 4-coumaryl-CoA + 3-oxooctanoyl-CoA + H2O <=> 4-coumaroylhexanoylmethane + 2 coenzyme A + carbon dioxide.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-12668									molecular_function											owl:Class	
GO:0010706	biolink:NamedThing	ganglioside biosynthetic process via lactosylceramide	The chemical reactions and pathways resulting in the formation of gangliosides that begins with the formation of lactosylceramides, Gal-beta-(1->4)-Glc-beta-(1->1') ceramides, any compound formed by the replacement of the glycosidic C1 hydroxyl group of lactose by a ceramide group.	tmpzr1t_l9r_go_relaxed.owl	lactosylceramide biosynthetic process leading to ganglioside|ganglioside biosynthesis via lactosylceramide biosynthesis|lactosylceramide biosynthesis leading to ganglioside|biosynthesis of lactosylceramide precursor to ganglioside													biological_process											owl:Class	
GO:0016057	biolink:NamedThing	regulation of membrane potential in photoreceptor cell	Hyperpolarization (vertebrates) or depolarization (invertebrates) of the photoreceptor cell membrane via closing/opening of cation specific channels as a result of signals generated by rhodopsin activation by a photon.	tmpzr1t_l9r_go_relaxed.owl	changes in polarization state of photoreceptor cell membrane													biological_process											owl:Class	
GO:1904435	biolink:NamedThing	regulation of transferrin receptor binding	Any process that modulates the frequency, rate or extent of transferrin receptor binding.	tmpzr1t_l9r_go_relaxed.owl								kom	2015-07-06T13:49:01Z					biological_process											owl:Class	
GO:0018914	biolink:NamedThing	chlorobenzene metabolic process	The chemical reactions and pathways involving chlorobenzene, a derivative of benzene with a chlorine atoms attached to the ring. It is a colorless liquid that is manufactured for use as a solvent. It quickly evaporates in the air and is degraded by hydroxyl radicals that are produced photochemically. The gas acts as a source of ClOx, which helps in the breakdown of stratospheric ozone.	tmpzr1t_l9r_go_relaxed.owl	chlorobenzene metabolism				UM-BBD_pathwayID:cb									biological_process											owl:Class	
GO:0046686	biolink:NamedThing	response to cadmium ion	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cadmium (Cd) ion stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to cadmium|cadmium sensitivity/resistance													biological_process											owl:Class	
GO:0008346	biolink:NamedThing	larval walking behavior	The behavior of a larval organism relating to the progression of that organism along the ground by the process of lifting and setting down each leg.	tmpzr1t_l9r_go_relaxed.owl	larval walking behaviour													biological_process											owl:Class	
GO:0031686	biolink:NamedThing	A1 adenosine receptor binding	Binding to an A1 adenosine receptor.	tmpzr1t_l9r_go_relaxed.owl	A1 adenosine receptor ligand													molecular_function											owl:Class	
GO:0033193	biolink:NamedThing	Lsd1/2 complex	A nucleosome-binding protein complex that comprises two SWIRM domain histone demethylases and two PHD finger proteins. The complex is involved in transcriptional regulation via heterochromatic silencing and the regulation of chromatin boundary formation, and was first identified in fission yeast.	tmpzr1t_l9r_go_relaxed.owl	Swm1/2 complex|SAPHIRE complex|Swm complex													cellular_component											owl:Class	
GO:0052843	biolink:NamedThing	inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity	Catalysis of the reaction: inositol 1-diphosphate 2,3,4,5,6-pentakisphosphate + H2O = inositol 1,2,3,4,5,6-hexakisphosphate + phosphate + 2 H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-10977			ai	2011-12-05T10:42:00Z					molecular_function											owl:Class	
GO:1905962	biolink:NamedThing	glutamatergic neuron differentiation	The process in which a relatively unspecialized cell acquires the specialized features of a glutamatergic neuron.	tmpzr1t_l9r_go_relaxed.owl								sl	2017-02-23T17:40:43Z					biological_process											owl:Class	
GO:0106326	biolink:NamedThing	acetylgalactosaminyl-O-glycosyl-threonyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity	Catalysis of the reaction: 3-O-[N-acetyl-beta-D-glucosaminyl-(1->3)-N-acetyl-alpha-D-galactosaminyl]-L-threonyl-[protein] + UDP-N-acetyl-alpha-D-glucosamine = 3-O-[N-acetyl-beta-D-glucosaminyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->6)]-N-acetyl-alpha-D-galactosaminyl]-L-threonyl-[protein] + H(+) + UDP.	tmpzr1t_l9r_go_relaxed.owl					RHEA:56192|EC:2.4.1.148			hjd	2020-09-30T13:40:25Z					molecular_function											owl:Class	
GO:1902698	biolink:NamedThing	pentose catabolic process to butyrate	The chemical reactions and pathways resulting in the breakdown of pentose to butyrate.	tmpzr1t_l9r_go_relaxed.owl	acidogenesis|pentose breakdown to butyrate|pentose catabolism to butyrate|pentose degradation to butyrate							tb	2014-02-19T18:28:28Z			GO:1990288		biological_process											owl:Class	
GO:0018793	biolink:NamedThing	3,5-dibromo-4-hydroxybenzoate decarboxylase activity	Catalysis of the reaction: 3,5-dibromo-4-hydroxybenzoate + H+ = CO2 + 2,6-dibromophenol.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0546									molecular_function											owl:Class	
GO:0031880	biolink:NamedThing	type 3 somatostatin receptor binding	Binding to a type 3 somatostatin receptor.	tmpzr1t_l9r_go_relaxed.owl	type 3 somatostatin receptor ligand													molecular_function											owl:Class	
GO:0046401	biolink:NamedThing	lipopolysaccharide core region metabolic process	The chemical reactions and pathways resulting in the formation of the core region of bacterial lipopolysaccharides, which contains ten saccharide residues. The structure of this core oligosaccharide appears to be similar in closely related bacterial strains.	tmpzr1t_l9r_go_relaxed.owl	LPS core region metabolic process|lipopolysaccharide core region metabolism													biological_process											owl:Class	
GO:0030959	biolink:NamedThing	peptide cross-linking via 3'-(3'-L-tyrosinyl)-L-tyrosine	The modification of two peptidyl-tyrosines to form a 3'-(3'-L-tyrosinyl)-L-tyrosine protein cross-link.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0367									biological_process											owl:Class	
GO:0043825	biolink:NamedThing	succinylornithine transaminase activity	Catalysis of the reaction: 2-oxoglutarate + N(2)-succinyl-L-ornithine = N-succinyl-L-glutamate 5-semialdehyde + L-glutamate.	tmpzr1t_l9r_go_relaxed.owl	N2-succinylornithine 5-aminotransferase activity|N(2)-succinylornithine 5-aminotransferase activity|succinyl ornithine transaminase activity|2-N-succinyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity|succinyl-ornithine transaminase activity|AstC|succinylornithine aminotransferase activity|N2-succinyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity|SOAT				MetaCyc:SUCCORNTRANSAM-RXN|EC:2.6.1.81|KEGG_REACTION:R04217|RHEA:16953									molecular_function											owl:Class	
GO:0044076	biolink:NamedThing	positive regulation by symbiont of host vacuole organization	The process in which a symbiont organism activates or increases the frequency, rate or extent of vacuole organization in its host organism.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of host vacuole organization by symbiont|positive regulation by symbiont of host vacuole organisation|positive regulation by symbiont of host vacuole biogenesis													biological_process											owl:Class	
GO:0033257	biolink:NamedThing	Bcl3/NF-kappaB2 complex	A protein complex containing one Bcl protein and one or more copies of NF-kappaB2; formation of complexes of different stoichiometry depends on the Bcl3:NF-kappaB2 ratio, and allow Bcl3 to exert different regulatory effects on NF-kappaB2-dependent transcription.	tmpzr1t_l9r_go_relaxed.owl	Bcl3-NFKB2 complex|Bcl3-p52 complex													cellular_component											owl:Class	
GO:0033256	biolink:NamedThing	I-kappaB/NF-kappaB complex	A protein complex containing an inhibitory-kappaB (I-kappaB/IKB) protein and one or more copies of an NF-kappaB protein. In the resting state, NF-kappaB dimers are bound to I-kappaB proteins, sequestering NF-kappaB in the cytoplasm.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0004329	biolink:NamedThing	formate-tetrahydrofolate ligase activity	Catalysis of the reaction: ATP + formate + tetrahydrofolate = ADP + phosphate + 10-formyltetrahydrofolate.	tmpzr1t_l9r_go_relaxed.owl	10-formyl-THF synthetase activity|tetrahydrofolic formylase activity|10-formyltetrahydrofolate synthetase activity|formyltetrahydrofolate synthetase activity|formate:tetrahydrofolate ligase (ADP-forming)|tetrahydrofolate formylase activity				RHEA:20221|Reactome:R-HSA-5696839|Reactome:R-HSA-6801456|MetaCyc:FORMATETHFLIG-RXN|EC:6.3.4.3|Reactome:R-HSA-200711									molecular_function											owl:Class	
GO:0106100	biolink:NamedThing	beta-pinacene synthase activity	Catalysis of the cyclization of geranylgeranyl pyrophosphate (GGPP) to yield the monocyclic diterpene beta-pinacene.	tmpzr1t_l9r_go_relaxed.owl								hjd	2018-02-15T16:51:59Z					molecular_function											owl:Class	
GO:0005642	biolink:NamedThing	annulate lamellae	Stacks of endoplasmic reticulum (ER) membranes containing a high density of nuclear pores, thought to form from excess nuclear membrane components, that have been described in a number of different cells. Annulate lamellar membranes are continuous with and embedded within the ER.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0102327	biolink:NamedThing	3-oxoacyl-CoA hydrolase activity	Catalysis of the reaction: H2O + a 3-oxoacyl-CoA = H+ + coenzyme A + a 3-oxoacid.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-13247									molecular_function											owl:Class	
GO:1901481	biolink:NamedThing	L-glutamate import involved in cellular response to nitrogen starvation	Any L-glutamate import that is involved in cellular response to nitrogen starvation.	tmpzr1t_l9r_go_relaxed.owl	L-glutamate uptake involved in cellular response to nitrogen starvation							al	2012-10-08T08:32:29Z					biological_process											owl:Class	
GO:0099103	biolink:NamedThing	channel activator activity	Direct interaction with a channel (binding or modification), resulting in its opening. A channel catalyzes energy-independent facilitated diffusion, mediated by passage of a solute through a transmembrane aqueous pore or channel.	tmpzr1t_l9r_go_relaxed.owl	channel gating activity													molecular_function											owl:Class	
GO:0016937	biolink:NamedThing	short-branched-chain-acyl-CoA dehydrogenase activity	Catalysis of the reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor, where the acyl group is a short branched chain fatty acid residue.	tmpzr1t_l9r_go_relaxed.owl					EC:1.3.99.-									molecular_function											owl:Class	
GO:0001401	biolink:NamedThing	SAM complex	A large complex of the mitochondrial outer membrane that mediates sorting of some imported proteins to the outer membrane and their assembly in the membrane; functions after import of incoming proteins by the mitochondrial outer membrane translocase complex.	tmpzr1t_l9r_go_relaxed.owl	TOB complex|mitochondrial sorting and assembly machinery complex					See also the cellular component term 'mitochondrial outer membrane translocase complex ; GO:0005742'.								cellular_component											owl:Class	
GO:0044053	biolink:NamedThing	translocation of peptides or proteins into host cell cytoplasm	The directed movement of peptides or proteins produced by a symbiont organism to a location within the host cell cytoplasm.	tmpzr1t_l9r_go_relaxed.owl	transport of peptides or proteins into host cell cytoplasm|translocation of symbiont peptides or proteins into host cell cytoplasm													biological_process											owl:Class	
GO:0019096	biolink:NamedThing	pole plasm mitochondrial lrRNA localization	Any process in which mitochondrial large ribosomal RNA is transported to, or maintained in, the oocyte pole plasm. An example of this is found in Drosophila melanogaster.	tmpzr1t_l9r_go_relaxed.owl	establishment and maintenance of mitochondrial lrRNA localization in pole plasm|oocyte pole plasm mitochondrial lrRNA localization|pole plasm mitochondrial lrRNA localisation											GO:0048118		biological_process											owl:Class	
GO:0046659	biolink:NamedThing	digestive hormone activity	The action characteristic of a hormone that takes part in the digestion process.	tmpzr1t_l9r_go_relaxed.owl	secretin													molecular_function											owl:Class	
GO:0048244	biolink:NamedThing	phytanoyl-CoA dioxygenase activity	Catalysis of the reaction: 2-oxoglutarate + O(2) + phytanoyl-CoA = 2-hydroxyphytanoyl-CoA + CO(2) + succinate.	tmpzr1t_l9r_go_relaxed.owl	phytanoyl-CoA, 2-oxoglutarate:oxygen oxidoreductase (2-hydroxylating)|phytanoyl-CoA 2-hydroxylase activity|phytanoyl-CoA 2 oxoglutarate dioxygenase activity|phytanoyl-CoA alpha-hydroxylase activity|phytanoyl-CoA hydroxylase activity				RHEA:16065|EC:1.14.11.18|KEGG_REACTION:R05722|Reactome:R-HSA-389639|MetaCyc:1.14.11.18-RXN									molecular_function											owl:Class	
GO:0042262	biolink:NamedThing	DNA protection	Any process in which DNA is protected from damage by, for example, oxidative stress.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0008803	biolink:NamedThing	bis(5'-nucleosyl)-tetraphosphatase (symmetrical) activity	Catalysis of the reaction: P(1),P(4)-bis(5'-adenosyl) tetraphosphate + H(2)O = 2 ADP + 2 H(+).	tmpzr1t_l9r_go_relaxed.owl	diadenosinetetraphosphatase (symmetrical) activity|diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolase activity|adenosine tetraphosphate phosphodiesterase activity|diadenosine 5',5'''-P(1),P(4)-tetraphosphate pyrophosphohydrolase activity|symmetrical diadenosine tetraphosphate hydrolase activity|dinucleosidetetraphosphate (symmetrical)|P1,P4-bis(5'-nucleosyl)-tetraphosphate nucleosidebisphosphohydrolase activity|diadenosine 5',5'''-P1,P4-tetraphosphatase activity|Ap4A hydrolase activity|diadenosine tetraphosphatase (symmetrical)|diadenosine tetraphosphate hydrolase activity|diadenosine polyphosphate hydrolase activity|1-P,4-P-bis(5'-nucleosyl)-tetraphosphate nucleosidebisphosphohydrolase activity|dinucleosidetetraphosphatase (symmetrical) activity|bis(5'-adenosyl) tetraphosphatase activity|Ap(4)A hydrolase activity				MetaCyc:3.6.1.41-RXN|EC:3.6.1.41|RHEA:24252|KEGG_REACTION:R00125									molecular_function											owl:Class	
GO:0106139	biolink:NamedThing	symbiont cell surface	The cell surface of a secondary, endosymbiont organism with which the first organism is interacting. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	endosymbiont cell surface							hjd	2018-08-15T18:56:57Z					cellular_component											owl:Class	
GO:0102664	biolink:NamedThing	indole-3-acetyl-leucine synthetase activity	Catalysis of the reaction: indole-3-acetate + L-leucine  + ATP <=> H+ + indole-3-acetyl-leucine + diphosphoric acid + AMP.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-2945									molecular_function											owl:Class	
GO:0060784	biolink:NamedThing	regulation of cell proliferation involved in tissue homeostasis	Any process that modulates the frequency, rate or extent of cell proliferation resulting in the maintenance of a steady-state number of cells within a tissue.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-07-31T01:46:28Z					biological_process											owl:Class	
GO:0050359	biolink:NamedThing	tropomyosin kinase activity	Catalysis of the reaction: ATP + tropomyosin = ADP + O-phosphotropomyosin.	tmpzr1t_l9r_go_relaxed.owl	tropomyosin kinase (phosphorylating) activity|STK|ATP:tropomyosin O-phosphotransferase activity				MetaCyc:TROPOMYOSIN-KINASE-RXN|EC:2.7.11.28									molecular_function											owl:Class	
GO:0046415	biolink:NamedThing	urate metabolic process	The chemical reactions and pathways involving urate, the anion of uric acid, 2,6,8-trioxypurine, the end product of purine metabolism in certain mammals and the main excretory product in uricotelic animals.	tmpzr1t_l9r_go_relaxed.owl	urate metabolism													biological_process											owl:Class	
GO:0047369	biolink:NamedThing	succinate-hydroxymethylglutarate CoA-transferase activity	Catalysis of the reaction: (S)-3-hydroxy-3-methylglutarate + succinyl-CoA = 3-hydroxy-3-methyl-glutaryl-CoA + succinate.	tmpzr1t_l9r_go_relaxed.owl	dicarboxyl-CoA:dicarboxylic acid coenzyme A transferase activity|succinate:(S)-3-hydroxy-3-methylglutarate CoA-transferase activity|hydroxymethylglutarate coenzyme A-transferase activity				MetaCyc:2.8.3.13-RXN|EC:2.8.3.13|RHEA:12284									molecular_function											owl:Class	
GO:0006821	biolink:NamedThing	chloride transport	The directed movement of chloride into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0003860	biolink:NamedThing	3-hydroxyisobutyryl-CoA hydrolase activity	Catalysis of the reaction: 3-hydroxy-2-methylpropanoyl-CoA + H2O = CoA + 3-hydroxy-2-methylpropanoate.	tmpzr1t_l9r_go_relaxed.owl	HIB CoA deacylase activity|3-hydroxy-isobutyryl CoA hydrolase activity|3-hydroxy-2-methylpropanoyl-CoA hydrolase activity				MetaCyc:3-HYDROXYISOBUTYRYL-COA-HYDROLASE-RXN|EC:3.1.2.4|RHEA:20888|Reactome:R-HSA-70881									molecular_function											owl:Class	
GO:0018472	biolink:NamedThing	1-hydroxy-2-naphthaldehyde dehydrogenase activity	Catalysis of the reaction: 1-hydroxy-2-naphthaldehyde + NAD+ + H2O = NADH + H+ + 1-hydroxy-2-naphthoate.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0485									molecular_function											owl:Class	
GO:0140608	biolink:NamedThing	cysteine-type endopeptidase activator activity	Binds to and increases the activity of a cysteine-type endopeptidase.	tmpzr1t_l9r_go_relaxed.owl	caspase activator activator activity	https://github.com/geneontology/go-ontology/issues/20916						pg	2021-02-18T08:58:58Z					molecular_function											owl:Class	
GO:0008780	biolink:NamedThing	acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity	Catalysis of the reaction: (R)-3-hydroxytetradecanoyl-[acyl-carrier protein] + UDP-N-acetylglucosamine = [acyl-carrier protein] + UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine.	tmpzr1t_l9r_go_relaxed.owl	acyl-[acyl-carrier protein]-UDP-N-acetylglucosamine O-acyltransferase activity|UDP-N-acetylglucosamine acyltransferase activity|acyl-acyl-carrier-protein-UDP-N-acetylglucosamine O-acyltransferase|uridine diphosphoacetylglucosamine acyltransferase activity|acyl-ACP-UDP-N-acetylglucosamine O-acyltransferase activity|(R)-3-hydroxytetradecanoyl-acyl-carrier-protein:UDP-N-acetylglucosamine 3-O-(3-hydroxytetradecanoyl)transferase activity				RHEA:13925|MetaCyc:UDPNACETYLGLUCOSAMACYLTRANS-RXN|EC:2.3.1.129									molecular_function											owl:Class	
GO:0043870	biolink:NamedThing	N-acetyl-gamma-aminoadipyl-phosphate reductase activity	Catalysis of the reaction: N(2)-acetyl-L-aminoadipate-semialdehyde + NADP+ + phosphate = N(2)-acetyl-L-gamma-aminoadipyl phosphate + NADPH.	tmpzr1t_l9r_go_relaxed.owl	ArgC|N-acetyl-alpha-glutamyl-phosphate reductase activity|AGPR|N-acetyl-aminoadipate semialdehyde dehydrogenase activity|NAGSA dehydrogenase activity|LysY				RHEA:41948|MetaCyc:RXN-5183	This function is part of the prokaryotic alpha-aminoadipate lysine biosynthesis pathway.								molecular_function											owl:Class	
GO:0000095	biolink:NamedThing	S-adenosyl-L-methionine transmembrane transporter activity	Enables the transfer of S-adenosylmethionine from one side of a membrane to the other. S-adenosylmethionine is S-(5'-adenosyl)-L-methionine, an important intermediate in one-carbon metabolism.	tmpzr1t_l9r_go_relaxed.owl	S-adenosyl methionine permease activity|SAM transmembrane transporter activity|S-adenosylmethionine transmembrane transporter activity|S-adenosyl methionine transporter activity|S-adenosylmethionine permease activity|S-adenosylmethionine transporter activity				Reactome:R-HSA-8855062							GO:0015177		molecular_function											owl:Class	
GO:0031908	biolink:NamedThing	glyoxysomal lumen	The volume enclosed by the membranes of a glyoxysome.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0047205	biolink:NamedThing	quinate O-hydroxycinnamoyltransferase activity	Catalysis of the reaction: feruloyl-CoA + quinate = O-feruloylquinate + CoA.	tmpzr1t_l9r_go_relaxed.owl	hydroxycinnamoyl coenzyme A-quinate transferase activity|feruloyl-CoA:quinate O-(hydroxycinnamoyl)transferase activity				RHEA:15021|EC:2.3.1.99|MetaCyc:2.3.1.99-RXN									molecular_function											owl:Class	
GO:1901527	biolink:NamedThing	abscisic acid-activated signaling pathway involved in stomatal movement	Any abscisic acid mediated signaling pathway that is involved in stomatal movement.	tmpzr1t_l9r_go_relaxed.owl	abscisic acid mediated signalling involved in stomatal movement|abscisic acid mediated signaling pathway involved in stomatal movement							tb	2012-10-23T23:09:34Z					biological_process											owl:Class	
GO:0005900	biolink:NamedThing	oncostatin-M receptor complex	A heterodimeric receptor for the cytokine oncostatin-M (OSM). In humans the receptor complex is made up of the gene products gp130 and OSMR-beta.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0060295	biolink:NamedThing	regulation of cilium movement involved in cell motility	Any process that modulates the rate frequency or extent of cilium movement involved in ciliary motility.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0036391	biolink:NamedThing	medial cortex septin ring	A ring-shaped structure that forms at the medial cortex of a symmetrically dividing cell at the onset of cytokinesis; composed of members of the conserved family of filament forming proteins called septins as well as septin-associated proteins.	tmpzr1t_l9r_go_relaxed.owl								bf	2013-06-06T16:12:06Z					cellular_component											owl:Class	
GO:1903611	biolink:NamedThing	negative regulation of calcium-dependent ATPase activity	Any process that stops, prevents or reduces the frequency, rate or extent of calcium-dependent ATPase activity.	tmpzr1t_l9r_go_relaxed.owl	down regulation of calcium-dependent ATPase activity|downregulation of calcium-dependent ATPase activity|down-regulation of calcium-dependent ATPase activity|inhibition of calcium-dependent ATPase activity							sl	2014-11-18T00:42:57Z					biological_process											owl:Class	
GO:0003960	biolink:NamedThing	NADPH:quinone reductase activity	Catalysis of the reaction: NADPH + H+ + quinone = NADP+ + semiquinone.	tmpzr1t_l9r_go_relaxed.owl	quinone oxidoreductase activity|zeta-crystallin activity|NADPH:quinone oxidoreductase activity				RHEA:14269|Reactome:R-HSA-6799722|EC:1.6.5.5|MetaCyc:QOR-RXN									molecular_function											owl:Class	
GO:0060655	biolink:NamedThing	branching involved in mammary gland cord morphogenesis	The process in which the branching structure of the mammary gland cord is generated and organized. The mammary gland cord is a solid epithelial structure that will hollow out, forming the mammary duct.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-05-29T09:29:32Z					biological_process											owl:Class	
GO:0018716	biolink:NamedThing	1-phenanthrol glycosyltransferase activity	Catalysis of the reaction: 1-phenanthrol + glucose = 1-phenanthryl-beta-D-glucopyranoside + H2O.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0525									molecular_function											owl:Class	
GO:0004079	biolink:NamedThing	biotin-[methylmalonyl-CoA-carboxytransferase] ligase activity	Catalysis of the reaction: ATP + biotin + apo-(methylmalonyl-CoA:pyruvate carboxytransferase) = AMP + diphosphate + (methylmalonyl-CoA:pyruvate carboxytransferase).	tmpzr1t_l9r_go_relaxed.owl	methylmalonyl coenzyme A holotranscarboxylase synthetase activity|biotin-methylmalonyl-CoA-carboxyltransferase synthetase|biotin--[methylmalonyl-CoA-carboxyltransferase] synthetase activity|biotin-transcarboxylase synthetase activity|biotin--[methylmalonyl-CoA-carboxyltransferase] ligase activity|biotin-methylmalonyl-CoA-carboxytransferase ligase activity|biotin-methylmalonyl coenzyme A carboxyltransferase synthetase activity|biotin-methylmalonyl-CoA-carboxyltransferase ligase activity|biotin:apomethylmalonyl-CoA:pyruvate carboxyltransferase ligase (AMP-forming)|biotin-methylmalonyl-CoA-carboxytransferase synthetase activity|biotin--[methylmalonyl-CoA-carboxytransferase] synthetase activity|biotin:apomethylmalonyl-CoA:pyruvate carboxytransferase ligase (AMP-forming)|biotin-[methylmalonyl-CoA-carboxyltransferase] ligase activity				MetaCyc:6.3.4.9-RXN|RHEA:23668|EC:6.3.4.9									molecular_function											owl:Class	
GO:0097317	biolink:NamedThing	invasive growth in response to biotic stimulus	The growth of colonies in filamentous chains of cells as a result of a biotic stimulus. An example of this is Candida albicans forming invasive filaments in agar medium in response to a serum stimulus.	tmpzr1t_l9r_go_relaxed.owl								pr	2012-05-31T10:38:16Z					biological_process											owl:Class	
GO:0035080	biolink:NamedThing	heat shock-mediated polytene chromosome puffing	The decondensing (loosening) and swelling of the chromosomal sites of heat shock genes on polytene chromosomes in response to a heat shock stimulus.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0061972	biolink:NamedThing	dermal bone morphogenesis	The process in which bone which forms superficially in the organism are generated and organized.	tmpzr1t_l9r_go_relaxed.owl								dph	2018-02-12T18:16:21Z					biological_process											owl:Class	
GO:0052718	biolink:NamedThing	tRNA-specific adenosine-34 deaminase complex	A protein complex that possesses tRNA-specific adenosine-34 deaminase activity. In eukaryotes the complex is a heterodimer; the subunits are known as Tad2p and Tad3p in yeasts and Adat2 and Adat3 in human.	tmpzr1t_l9r_go_relaxed.owl	tRNA-A34 deaminase complex							ai	2011-08-12T11:53:26Z					cellular_component											owl:Class	
GO:1901198	biolink:NamedThing	positive regulation of calcium ion transport into cytosol involved in cellular response to calcium ion	Any positive regulation of calcium ion transport into cytosol that is involved in cellular response to calcium ion.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of calcium ion transport into cytosol involved in cellular response to Ca2+ ion							al	2012-07-27T11:07:43Z					biological_process											owl:Class	
GO:1902793	biolink:NamedThing	glutamate decarboxylase complex	A protein complex which is capable of glutamate decarboxylase activity.	tmpzr1t_l9r_go_relaxed.owl						An example of this is GAD1 in human (Q99259) in PMID:17384644 (inferred from direct assay).		bhm	2014-03-24T10:59:45Z					cellular_component											owl:Class	
GO:1905325	biolink:NamedThing	regulation of meiosis I spindle assembly checkpoint	Any process that modulates the frequency, rate or extent of the meiosis I spindle assembly checkpoint.	tmpzr1t_l9r_go_relaxed.owl								mah	2016-07-20T12:48:40Z					biological_process											owl:Class	
GO:0030268	biolink:NamedThing	methylenetetrahydromethanopterin dehydrogenase activity	Catalysis of the reaction: 5,10-methylenetetrahydromethanopterin + coenzyme F420 + 2 H(+) = 5,10-methenyl-5,6,7,8-tetrahydromethanopterin + reduced coenzyme F420.	tmpzr1t_l9r_go_relaxed.owl	N(5),N(10)-methylenetetrahydromethanopterin dehydrogenase activity|5,10-methylenetetrahydromethanopterin:coenzyme-F420 oxidoreductase activity|5,10-methylenetetrahydromethanopterin dehydrogenase activity				MetaCyc:1.5.99.9-RXN|KEGG_REACTION:R04456|RHEA:16721|UM-BBD_reactionID:r0348|EC:1.5.98.1							GO:0018536		molecular_function											owl:Class	
GO:1905593	biolink:NamedThing	positive regulation of optical nerve axon regeneration	Any process that activates or increases the frequency, rate or extent of optical nerve axon regeneration.	tmpzr1t_l9r_go_relaxed.owl	activation of optical nerve axon regeneration|upregulation of optical nerve axon regeneration|up-regulation of optical nerve axon regeneration|up regulation of optical nerve axon regeneration							pga	2016-10-25T12:58:58Z					biological_process											owl:Class	
GO:1904673	biolink:NamedThing	negative regulation of somatic stem cell population maintenance	Any process that stops, prevents or reduces the frequency, rate or extent of somatic stem cell population maintenance.	tmpzr1t_l9r_go_relaxed.owl	downregulation of somatic stem cell population maintenance|down-regulation of somatic stem cell population maintenance|down regulation of somatic stem cell population maintenance|inhibition of somatic stem cell population maintenance							rph	2015-09-14T08:40:25Z					biological_process											owl:Class	
GO:1904609	biolink:NamedThing	cellular response to monosodium L-glutamate	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monosodium L-glutamate stimulus.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-08-27T18:43:14Z					biological_process											owl:Class	
GO:0120023	biolink:NamedThing	somatostatin binding	Binding to somatostatin, a polypeptide hormone involved in regulating pancreatic alpha and pancreatic beta cells and controlling growth hormone secretion as well as many other functions. Somatostatin is produced by several cell types including pancreatic delta cells. There are several different mature forms of somatostatin.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/13143						krc	2017-03-17T14:54:21Z					molecular_function											owl:Class	
GO:0102549	biolink:NamedThing	1-18:1-2-16:0-monogalactosyldiacylglycerol lipase activity	Catalysis of the reaction: 1-18:1-2-16:0-monogalactosyldiacylglycerol + H2O <=> sn-1-lyso-2-16:0-monogalactosyldiacylglycerol + oleate + H+.	tmpzr1t_l9r_go_relaxed.owl					EC:3.1.1.26|MetaCyc:RXN-14912									molecular_function											owl:Class	
GO:0004418	biolink:NamedThing	hydroxymethylbilane synthase activity	Catalysis of the reaction: H(2)O + 4 porphobilinogen = hydroxymethylbilane + 4 NH(4)(+).	tmpzr1t_l9r_go_relaxed.owl	pre-uroporphyrinogen synthase activity|(4-(2-carboxyethyl)-3-(carboxymethyl)pyrrol-2-yl)methyltransferase (hydrolyzing) activity|uroporphyrinogen synthetase activity|porphobilinogen:(4-[2-carboxyethyl]-3-[carboxymethyl]pyrrol-2-yl)methyltransferase (hydrolysing)|uroporphyrinogen synthase activity|(4-[2-carboxyethyl]-3-[carboxymethyl]pyrrol-2-yl)methyltransferase (hydrolysing)|porphobilinogen deaminase activity|porphobilinogen ammonia-lyase (polymerizing)|uroporphyrinogen I synthetase activity|HMB-synthase activity|uroporphyrinogen I synthase activity				RHEA:13185|MetaCyc:OHMETHYLBILANESYN-RXN|EC:2.5.1.61|KEGG_REACTION:R00084|Reactome:R-HSA-189406	Note that this function was formerly EC:4.3.1.8.								molecular_function											owl:Class	
GO:0097219	biolink:NamedThing	compound sieve plate	A sieve plate that contains several specialized sieve areas in either a scalariform or reticulate arrangement.	tmpzr1t_l9r_go_relaxed.owl						Often located on an end wall of a sieve tube member. Unspecialized sieve areas may occur on other parts of the cell.		pr	2012-01-13T05:45:23Z					cellular_component											owl:Class	
GO:0003409	biolink:NamedThing	optic cup structural organization	The process that contributes to creating the structural organization of the optic cup. This process pertains to the physical shaping of the rudimentary structure.	tmpzr1t_l9r_go_relaxed.owl	optic cup structural organisation							dph	2009-12-21T02:44:20Z					biological_process											owl:Class	
GO:0019654	biolink:NamedThing	acetate fermentation	The anaerobic chemical reactions and pathways resulting in the breakdown of acetate, yielding energy in the form of ATP.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:P142-PWY									biological_process											owl:Class	
GO:0072386	biolink:NamedThing	plus-end-directed organelle transport along microtubule	The directed movement of an organelle towards the plus end of a microtubule, mediated by motor proteins. This process begins with the attachment of an organelle to a microtubule, and ends when the organelle reaches its final destination.	tmpzr1t_l9r_go_relaxed.owl	microtubule plus-end-directed organelle distribution|microtubule plus-end-directed organelle localization							mah	2010-12-01T05:02:09Z					biological_process											owl:Class	
GO:0031533	biolink:NamedThing	mRNA cap methyltransferase complex	A protein complex that consists of an RNA 5' triphosphatase and a guanyl transferase (Cet1p and Ceg1p in S. cerevisiae; Pct1 and Ceg1 in S. pombe) and is involved in mRNA capping.	tmpzr1t_l9r_go_relaxed.owl	mRNA (guanine-N7) methyltransferase complex|mRNA capping enzyme complex													cellular_component											owl:Class	
GO:0045964	biolink:NamedThing	positive regulation of dopamine metabolic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving dopamine.	tmpzr1t_l9r_go_relaxed.owl	activation of dopamine metabolic process|up-regulation of dopamine metabolic process|positive regulation of dopamine metabolism|stimulation of dopamine metabolic process|upregulation of dopamine metabolic process|up regulation of dopamine metabolic process													biological_process											owl:Class	
GO:0021659	biolink:NamedThing	rhombomere 3 structural organization	The process that contributes to creating the structural organization of rhombomere 3. This process pertains to the physical shaping of a rudimentary structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.	tmpzr1t_l9r_go_relaxed.owl	rhombomere 3 structural organisation													biological_process											owl:Class	
GO:0120269	biolink:NamedThing	ciliary centrin arm	A rod-shaped protein complex containing Centrin4 protein that flanks the flagellum attachment zone (FAZ) filament and the quartet microtubules.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/20062				Note that cilia and eukaryotic flagella are deemed to be equivalent. In diplomonad species, such as Giardia, the axoneme may extend intracellularly up to 5um away from the plane of the plasma membrane.		krc	2020-09-30T18:20:22Z					cellular_component											owl:Class	
GO:0031819	biolink:NamedThing	P2Y10 nucleotide receptor binding	Binding to a P2Y10 nucleotide receptor.	tmpzr1t_l9r_go_relaxed.owl	P2Y10 nucleotide receptor ligand													molecular_function											owl:Class	
GO:0102688	biolink:NamedThing	dihydrozeatin UDP glycosyltransferase activity	Catalysis of the reaction: UDP-alpha-D-glucose + dihydrozeatin <=> H+ + 9-(alpha-D-glucosyl)dihydrozeatin + UDP.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-4725									molecular_function											owl:Class	
GO:0047785	biolink:NamedThing	cortisol sulfotransferase activity	Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + cortisol = adenosine 3',5'-diphosphate + cortisol 21-sulfate + H(+).	tmpzr1t_l9r_go_relaxed.owl	glucocorticoid sulfotransferase activity|cortisol sulphotransferase activity|3'-phosphoadenylyl-sulfate:cortisol 21-sulfotransferase activity|glucocorticosteroid sulfotransferase activity				KEGG_REACTION:R02839|MetaCyc:CORTISOL-SULFOTRANSFERASE-RXN|EC:2.8.2.18|RHEA:11884									molecular_function											owl:Class	
GO:0006607	biolink:NamedThing	NLS-bearing protein import into nucleus	The directed movement of a protein bearing a nuclear localization signal (NLS) from the cytoplasm into the nucleus, across the nuclear envelope.	tmpzr1t_l9r_go_relaxed.owl	NLS-bearing substrate import into nucleus|NLS-bearing substrate import into cell nucleus|NLS-bearing substrate transport from cytoplasm to nucleus|NLS-bearing substrate-nucleus import													biological_process											owl:Class	
GO:0042620	biolink:NamedThing	poly(3-hydroxyalkanoate) metabolic process	The chemical reactions and pathways involving poly(3-hydroxyalkanoates), polyesters of 3-hydroxyacids produced as intracellular granules by a large variety of bacteria.	tmpzr1t_l9r_go_relaxed.owl	poly(3-hydroxyalkanoate) metabolism|PHA metabolism|PHA metabolic process													biological_process											owl:Class	
GO:0004157	biolink:NamedThing	dihydropyrimidinase activity	Catalysis of the reaction: 5,6-dihydrouracil + H2O = 3-ureidopropionate.	tmpzr1t_l9r_go_relaxed.owl	hydantoin peptidase activity|hydropyrimidine hydrase activity|pyrimidine hydrase activity|5,6-dihydropyrimidine amidohydrolase activity|D-hydantoinase activity|hydantoinase activity				EC:3.5.2.2|Reactome:R-HSA-73618|MetaCyc:DIHYDROPYRIMIDINASE-RXN|Reactome:R-HSA-73589|RHEA:16121									molecular_function											owl:Class	
GO:0048924	biolink:NamedThing	posterior lateral line neuromast mantle cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a posterior lateral line neuromast mantle cell. (N.B. This may be development of neuromast mantle cell type or a set of cells of neuromast mantle cell type. This will involve the change of a cell or set of cells from one cell identity to another). Mantle cells are non-sensory cells that surround the sensory strip, separating the neuromast from the epidermis. Mantle cells secrete the cupula in which the ciliary bundles of all of the hair cells are embedded.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0051391	biolink:NamedThing	tRNA acetylation	The modification of tRNA structure by addition of an acetyl group to tRNA. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0043964	biolink:NamedThing	induction by symbiont of host adenylate cyclase-mediated signal transduction	Any process in which an organism activates, maintains or increases the frequency, rate or extent of adenylate cyclase-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	positive regulation by symbiont of host adenylate cyclase-mediated signal transduction													biological_process											owl:Class	
GO:0043963	biolink:NamedThing	modulation by symbiont of host adenylate cyclase-mediated signal transduction	Any process in which the symbiont modulates the frequency, rate or extent of adenylate cyclase-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0030034	biolink:NamedThing	microvillar actin bundle assembly	Assembly of the parallel bundle of actin filaments at the core of a microvillus.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0047259	biolink:NamedThing	glucomannan 4-beta-mannosyltransferase activity	Catalysis of the reaction: glucomannan(n) + GDP-mannose = glucomannan(n+1) + GDP.	tmpzr1t_l9r_go_relaxed.owl	glucomannan 4-b-mannosyltransferase activity|GDP-mannose:glucomannan 1,4-beta-D-mannosyltransferase activity|glucomannan-synthase activity|GDP-man-beta-mannan mannosyltransferase activity				EC:2.4.1.32|MetaCyc:2.4.1.32-RXN									molecular_function											owl:Class	
GO:1990417	biolink:NamedThing	snoRNA release from pre-rRNA	The release of snoRNA from pre-rRNA.	tmpzr1t_l9r_go_relaxed.owl						An example of this process is yeast HAS1 from PMID:16908538, inferred from mutant phenotype assay.		rb	2014-07-11T21:43:27Z					biological_process											owl:Class	
GO:0009088	biolink:NamedThing	threonine biosynthetic process	The chemical reactions and pathways resulting in the formation of threonine (2-amino-3-hydroxybutyric acid), a polar, uncharged, essential amino acid found in peptide linkage in proteins.	tmpzr1t_l9r_go_relaxed.owl	threonine anabolism|threonine biosynthesis|threonine formation|threonine synthesis				MetaCyc:HOMOSER-THRESYN-PWY|MetaCyc:THRESYN-PWY									biological_process											owl:Class	
GO:0102496	biolink:NamedThing	GA5 2,3 epoxidase activity	Catalysis of the reaction: gibberellin A5 + O2 + 2-oxoglutarate <=> gibberellin A6 + succinate + carbon dioxide.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-14327									molecular_function											owl:Class	
GO:0070437	biolink:NamedThing	Grb2-Shc complex	A protein complex that contains Grb2 and the adaptor protein Shc, and is involved in linking epidermal growth factor receptor (EGFR) activation to the p21-Ras pathway.	tmpzr1t_l9r_go_relaxed.owl	Grb2-Shc complex, EGF stimulated													cellular_component											owl:Class	
GO:0008764	biolink:NamedThing	UDP-N-acetylmuramoylalanine-D-glutamate ligase activity	Catalysis of the reaction: D-glutamate + ATP + UDP-N-acetylmuramoyl-L-alanine = ADP + 2 H(+) + phosphate + UDP-N-acetylmuramoyl-L-alanyl-D-glutamate.	tmpzr1t_l9r_go_relaxed.owl	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase activity|UDP-N-acetylmuramoyl-L-alanine:glutamate ligase (ADP-forming)|UDP-Mur-NAC-L-Ala:D-Glu ligase activity|uridine diphospho-N-acetylmuramoylalanyl-D-glutamate synthetase activity|D-glutamate-adding enzyme activity|D-glutamate ligase activity|MurD synthetase activity				EC:6.3.2.9|MetaCyc:UDP-NACMURALA-GLU-LIG-RXN|KEGG_REACTION:R02783|RHEA:16429									molecular_function											owl:Class	
GO:0003962	biolink:NamedThing	cystathionine gamma-synthase activity	Catalysis of the reaction: O-succinyl-L-homoserine + L-cysteine = cystathionine + succinate.	tmpzr1t_l9r_go_relaxed.owl	CTT gamma synthase activity|O-succinyl-L-homoserine (thiol)-lyase activity|cystathionine synthase activity|homoserine O-transsuccinylase activity|cystathionine gamma synthase activity|cystathionine synthetase activity|O-succinylhomoserine (thiol)-lyase activity|O-succinylhomoserine synthetase activity|cystathionine g-synthase activity|O-succinyl-L-homoserine succinate-lyase activity|homoserine transsuccinylase activity|O4-succinyl-L-homoserine:L-cysteine S-(3-amino-3-carboxypropyl)transferase activity|O-succinyl-L-homoserine succinate-lyase (adding cysteine) activity|O-succinylhomoserine synthase activity				RHEA:20397|MetaCyc:O-SUCCHOMOSERLYASE-RXN|EC:2.5.1.48							GO:0000505		molecular_function											owl:Class	
GO:0034790	biolink:NamedThing	3,4-dihydroxy-3,4-dihydrofluorene dehydrogenase activity	Catalysis of the reaction: (+)-(3S,4R)-cis-3,4-dihydroxy-3,4-dihydrofluorene = 3,4-dihydroxyfluorene + 2 H+ + 2 e-.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r1043									molecular_function											owl:Class	
GO:0047199	biolink:NamedThing	phosphatidylcholine-dolichol O-acyltransferase activity	Catalysis of the reaction: 1,2-diacyl-sn-glycero-3-phosphocholine + dolichol = 1-acyl-sn-glycero-3-phosphocholine + acyldolichol.	tmpzr1t_l9r_go_relaxed.owl	3-sn-phosphatidylcholine:dolichol O-acyltransferase activity				KEGG_REACTION:R04227|RHEA:19285|EC:2.3.1.83|MetaCyc:2.3.1.83-RXN									molecular_function											owl:Class	
GO:0018820	biolink:NamedThing	cyanamide hydratase activity	Catalysis of the reaction: urea = cyanamide + H(2)O.	tmpzr1t_l9r_go_relaxed.owl	urea hydro-lyase (cyanamide-forming)|urea hydro-lyase activity				EC:4.2.1.69|KEGG_REACTION:R00778|MetaCyc:CYANAMIDE-HYDRATASE-RXN|UM-BBD_reactionID:r0668|RHEA:23056									molecular_function											owl:Class	
GO:0004412	biolink:NamedThing	homoserine dehydrogenase activity	Catalysis of the reaction: L-homoserine + NADP+ = L-aspartate-4-semialdehyde + NADPH + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:HOMOSERDEHYDROG-RXN|RHEA:15761|EC:1.1.1.3									molecular_function											owl:Class	
GO:0062040	biolink:NamedThing	fungal biofilm matrix	An extracellular matrix lying external to fungal cells. The fungal biofilm matrix consists of polysaccharides, proteins, lipids, and nucleic acids. Fungal biofilms mediate adherence to host tissues, and provide protection from host immune defenses.	tmpzr1t_l9r_go_relaxed.owl								dph	2018-05-04T12:54:39Z					cellular_component											owl:Class	
GO:2000025	biolink:NamedThing	regulation of leaf formation	Any process that modulates the frequency, rate or extent of leaf formation.	tmpzr1t_l9r_go_relaxed.owl								tb	2010-08-05T11:25:37Z					biological_process											owl:Class	
GO:0090059	biolink:NamedThing	protoxylem development	The process whose specific outcome is the progression of the protoxylem over time, from its formation to the mature structure. The protoxylem comprises the first formed elements of the primary xylem.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-08-11T03:08:06Z					biological_process											owl:Class	
GO:0007087	biolink:NamedThing	mitotic nuclear pore complex reassembly	The cell cycle process in which nuclear pore complexes reform during mitotic cell division.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0097462	biolink:NamedThing	Lewy neurite	Elongated neuronal process, often with side branches and more than one branching point, described in brains of patients with Parkinson's disease. Lewy neurites stain positively for ubiquitin in brainstem and forebrain regions affected in Parkinson's disease.	tmpzr1t_l9r_go_relaxed.owl					NIF_Subcellular:sao601362597			pr	2012-12-21T07:57:58Z					cellular_component											owl:Class	
GO:0035632	biolink:NamedThing	mitochondrial prohibitin complex	A complex composed of two proteins, prohibitin 1 and prohibitin 2 (PHB1/PHB-1 and PHB2/PHB-2) that is highly conserved amongst eukaryotes and associated with the inner mitochondrial membrane. The mitochondrial prohibitin complex is a macromolecular supercomplex composed of repeating heterodimeric subunits of PHB1 and PHB2. The mitochondrial prohibitin complex plays a role in a number of biological processes, including mitochondrial biogenesis and function, development, replicative senescence, and cell death.	tmpzr1t_l9r_go_relaxed.owl	mitochondrial inner membrane prohibitin complex							bf	2010-12-21T10:38:59Z					cellular_component											owl:Class	
GO:0030170	biolink:NamedThing	pyridoxal phosphate binding	Binding to pyridoxal 5' phosphate, 3-hydroxy-5-(hydroxymethyl)-2-methyl4-pyridine carboxaldehyde 5' phosphate, the biologically active form of vitamin B6.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0106063	biolink:NamedThing	G protein-coupled folate receptor activity	Combining with folate and transmitting the signal from one side of the membrane to the other by activating an associated G-protein, initiating a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	G-protein coupled folic acid receptor activity|G-protein coupled folate receptor activity							hjd	2017-10-27T17:10:07Z					molecular_function											owl:Class	
GO:1990224	biolink:NamedThing	NMN phosphatase activity	Catalysis of the reaction: beta-nicotinamide D-ribonucleotide (NMN-) + H2O = beta-nicotinamide D-riboside (nicotinamide ribose, NmR) + phosphate.	tmpzr1t_l9r_go_relaxed.owl	nicotinamide mononucleotide phosphatase activity|beta-nicotinamide D-ribonucleotide phosphatase activity				RHEA:30815			rb	2013-10-21T18:03:41Z					molecular_function											owl:Class	
GO:0102948	biolink:NamedThing	luteolin C-glucosyltransferase activity	Catalysis of the reaction: 2-(3,4-dihydroxyphenyl)-5-hydroxy-4-oxo-4H-chromen-7-olate luteolin-7-olate + a glucosylated glucose acceptor = isoorientin + a non glucosylated glucose acceptor.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-9081									molecular_function											owl:Class	
GO:0047596	biolink:NamedThing	6-methylsalicylate decarboxylase activity	Catalysis of the reaction: 6-methylsalicylate + H(+) = 3-cresol + CO(2).	tmpzr1t_l9r_go_relaxed.owl	6-methylsalicylate carboxy-lyase activity|6-methylsalicylic acid (2,6-cresotic acid) decarboxylase activity|6-MSA decarboxylase activity|6-methylsalicylate carboxy-lyase (3-cresol-forming)				EC:4.1.1.52|KEGG_REACTION:R03567|RHEA:23112|MetaCyc:6-METHYLSALICYLATE-DECARBOXYLASE-RXN									molecular_function											owl:Class	
GO:0062131	biolink:NamedThing	3-butenylglucosinolate 2-hydroxylase activity	Catalysis of the reaction: gluconapin + a reduced electron acceptor + O2 = xi-progoitrin + an oxidized electron acceptor + H2O.	tmpzr1t_l9r_go_relaxed.owl	But-3-enyl Glucosinolate-2-hydroxylase activity				RHEA:60628|MetaCyc:RXNQT-4343			dph	2019-06-24T16:45:18Z					molecular_function											owl:Class	
GO:0097467	biolink:NamedThing	type III terminal bouton	Terminal inflated portion of the axon of a non-glutamatergic neuron, containing the specialized apparatus necessary to release neurotransmitters at a regulatory synapse. The axon terminus is considered to be the whole region of thickening and the terminal bouton is a specialized region of it. Type III terminal boutons are larger than type II ones.	tmpzr1t_l9r_go_relaxed.owl	type III terminal button							pr	2013-02-06T09:39:18Z					cellular_component											owl:Class	
GO:0050608	biolink:NamedThing	vanillin dehydrogenase activity	Catalysis of the reaction: H(2)O + NAD(+) + vanillin = 2 H(+) + NADH + vanillate.	tmpzr1t_l9r_go_relaxed.owl	vanillin:NAD+ oxidoreductase activity				MetaCyc:1.2.1.67-RXN|KEGG_REACTION:R05699|RHEA:13309|EC:1.2.1.67									molecular_function											owl:Class	
GO:0106293	biolink:NamedThing	NADH oxidase H202-forming activity	Catalysis of the reaction: NADH + H+ + O2 = NAD + hydrogen peroxide (H2O2).	tmpzr1t_l9r_go_relaxed.owl					RHEA:11264			hjd	2020-08-19T17:35:22Z					molecular_function											owl:Class	
GO:0039721	biolink:NamedThing	peristromal region viral factory	A nuclear viral factory formed at the periphery of the host cell nucleus by Baculoviruses.	tmpzr1t_l9r_go_relaxed.owl	PR							bf	2013-12-19T15:54:00Z					cellular_component											owl:Class	
GO:0051989	biolink:NamedThing	coproporphyrinogen dehydrogenase activity	Catalysis of the reaction: coproporphyrinogen III + 2 S-adenosyl-L-methionine = protoporphyrinogen IX + 2 CO2 + 2 L-methionine + 2 5'-deoxyadenosine.	tmpzr1t_l9r_go_relaxed.owl	HemN|coproporphyrinogen-III:S-adenosyl-L-methionine oxidoreductase (decarboxylating)|oxygen-independent coproporphyrinogen-III oxidase activity|radical SAM enzyme activity|coproporphyrinogen III oxidase activity				EC:1.3.98.3|RHEA:15425|MetaCyc:HEMN-RXN									molecular_function											owl:Class	
GO:0017125	biolink:NamedThing	deoxycytidyl transferase activity	Catalysis of the insertion of a dCMP residue opposite a template abasic site in DNA.	tmpzr1t_l9r_go_relaxed.owl	deoxycytidyl transferase activity, template-dependent				Reactome:R-HSA-110308							GO:0019986		molecular_function											owl:Class	
GO:0042334	biolink:NamedThing	taxis to electron acceptor	The directed movement of a motile cell or organism in response to the presence of an alternative electron acceptor, for example, nitrate.	tmpzr1t_l9r_go_relaxed.owl	taxis in response to electron acceptor													biological_process											owl:Class	
GO:0072371	biolink:NamedThing	histone kinase activity (H2A-S121 specific)	Catalysis of the transfer of a phosphate group to the serine-121 residue of the N-terminal tail of histone H2A.	tmpzr1t_l9r_go_relaxed.owl	histone-serine kinase activity (H2A-S121 specific)|histone serine kinase activity (H2A-S121 specific)							mah	2010-11-16T03:42:59Z					molecular_function											owl:Class	
GO:0061593	biolink:NamedThing	sulfoquinovose isomerase activity	Catalysis of the reaction sulfoquinovose = 6-deoxy-6-sulfofructose.	tmpzr1t_l9r_go_relaxed.owl								dph	2014-02-10T09:56:04Z					molecular_function											owl:Class	
GO:0034867	biolink:NamedThing	2,4,4-trimethylpent-2-enoyl-CoA hydratase activity	Catalysis of the reaction: 2,4,4-trimethylpent-2-enoyl-CoA + H2O = 2,4,4-trimethyl-3-hydroxypentanoyl-CoA.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r1277									molecular_function											owl:Class	
GO:0032942	biolink:NamedThing	inositol tetrakisphosphate 2-kinase activity	Catalysis of the reaction: 1D-myo-inositol tetrakisphosphate + ATP = 1D-myo-inositol pentakisphosphate (containing 2-phosphate) + ADP.	tmpzr1t_l9r_go_relaxed.owl	1D-myo-inositol-tetrakisphosphate 2-kinase activity|inositol 1,3,4,6-tetrakisphosphate 2-kinase activity|inositol-tetrakisphosphate 2-kinase activity				EC:2.7.1.-									molecular_function											owl:Class	
GO:0085042	biolink:NamedThing	periarbuscular membrane	A host-derived membrane surrounding the symbiont arbuscule during symbiosis.	tmpzr1t_l9r_go_relaxed.owl						See also: arbuscule ; GO:0085041.		jl	2010-07-27T04:31:37Z					cellular_component											owl:Class	
GO:0036334	biolink:NamedThing	epidermal stem cell homeostasis	Any biological process involved in the maintenance of the steady-state number of epidermal stem cells within a population of cells.	tmpzr1t_l9r_go_relaxed.owl								bf	2012-09-05T10:21:23Z					biological_process											owl:Class	
GO:0061412	biolink:NamedThing	positive regulation of transcription from RNA polymerase II promoter in response to amino acid starvation	Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of deprivation of amino acids.	tmpzr1t_l9r_go_relaxed.owl								dph	2012-01-12T12:54:05Z					biological_process											owl:Class	
GO:0032294	biolink:NamedThing	peripheral nervous system non-myelinated axon ensheathment	The process in which a non-myelinating Schwann cell membrane encircles an axon in the peripheral nervous system. A single non-myelinating Schwann cell will typically associate with multiple axons.	tmpzr1t_l9r_go_relaxed.owl	ensheathment of non-myelinated axons in peripheral nervous system													biological_process											owl:Class	
GO:0010148	biolink:NamedThing	transpiration	Release of water by the plant into the air as water vapor mainly through leaves.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Transpiration									biological_process											owl:Class	
GO:0140226	biolink:NamedThing	RNA topoisomerase activity	Catalysis of the transient cleavage and passage of individual RNA strands or double helices through one another, resulting a topological transformation in RNA.	tmpzr1t_l9r_go_relaxed.owl								pg	2018-05-29T11:06:37Z					molecular_function											owl:Class	
GO:0008358	biolink:NamedThing	maternal determination of anterior/posterior axis, embryo	The specification of the anterior/posterior axis of the embryo by gradients of maternally-transcribed gene products; exemplified in insects by the morphogens, bicoid and nanos.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0004978	biolink:NamedThing	corticotropin receptor activity	Combining with corticotropin to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	ACTH receptor activity|adrenocorticotropin receptor activity|adrenocorticotropic hormone receptor activity													molecular_function											owl:Class	
GO:0051916	biolink:NamedThing	granulocyte colony-stimulating factor binding	Binding to granulocyte colony-stimulating factor, G-CSF.	tmpzr1t_l9r_go_relaxed.owl	granulocyte colony stimulating factor binding|G-CSF binding													molecular_function											owl:Class	
GO:0061969	biolink:NamedThing	maintenance of left sidedness	The organization process that preserves the left sidedness in an organism's body plan or part of an organism with respect to the left and right halves.	tmpzr1t_l9r_go_relaxed.owl								dph	2018-02-12T16:41:30Z					biological_process											owl:Class	
GO:0004078	biolink:NamedThing	biotin-[methylcrotonoyl-CoA-carboxylase] ligase activity	Catalysis of the reaction: ATP + biotin + apo-(3-methylcrotonoyl-CoA:carbon-dioxide ligase (ADP-forming)) = AMP + diphosphate + (3-methylcrotonoyl-CoA:carbon-dioxide ligase (ADP-forming)).	tmpzr1t_l9r_go_relaxed.owl	biotin-methylcrotonoyl-CoA-carboxylase synthetase|biotin--[methylcrotonoyl-CoA-carboxylase] synthetase activity|biotin:apo-3-methylcrotonoyl-CoA:carbon-dioxide ligase (ADP-forming) ligase (AMP-forming)|biotin-methylcrotonoyl-CoA-carboxylase ligase activity|beta-methylcrotonyl coenzyme A holocarboxylase synthetase activity|biotin-beta-methylcrotonyl coenzyme A carboxylase synthetase activity				RHEA:24376|MetaCyc:6.3.4.11-RXN|EC:6.3.4.11									molecular_function											owl:Class	
GO:1900333	biolink:NamedThing	regulation of methane biosynthetic process from 3-(methylthio)propionic acid	Any process that modulates the frequency, rate or extent of methane biosynthetic process from 3-(methylthio)propionic acid.	tmpzr1t_l9r_go_relaxed.owl								tt	2012-04-06T01:56:13Z					biological_process											owl:Class	
GO:0003841	biolink:NamedThing	1-acylglycerol-3-phosphate O-acyltransferase activity	Catalysis of the reaction: acyl-CoA + 1-acyl-sn-glycerol-3-phosphate = CoA + 1,2-diacyl-sn-glycerol-3-phosphate.	tmpzr1t_l9r_go_relaxed.owl	1-acyl-sn-glycerol 3-phosphate acyltransferase activity|1-acylglycero-3-phosphate acyltransferase activity|acyl-CoA:1-acyl-sn-glycerol-3-phosphate 2-O-acyltransferase activity|1-acylglycerophosphate acyltransferase activity|lysophosphatidic acid-acyltransferase activity|lysophosphatidate acyltransferase activity|1-acyl-sn-glycero-3-phosphate acyltransferase activity|1-acylglycerolphosphate acyltransferase activity|1-acyl-sn-glycerol-3-phosphate acyltransferase activity				Reactome:R-HSA-1482636|Reactome:R-HSA-8849345|Reactome:R-HSA-1482548|MetaCyc:RXN-1623|Reactome:R-HSA-1482598|Reactome:R-HSA-75885|Reactome:R-HSA-1482667|Reactome:R-HSA-1482894|Reactome:R-HSA-1482539|Reactome:R-HSA-1482547|RHEA:19709|EC:2.3.1.51|Reactome:R-HSA-1482689							GO:0004469		molecular_function											owl:Class	
GO:0004069	biolink:NamedThing	L-aspartate:2-oxoglutarate aminotransferase activity	Catalysis of the reaction: L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate.	tmpzr1t_l9r_go_relaxed.owl	oxaloacetate-aspartate aminotransferase activity|L-aspartate transaminase activity|aspartic acid aminotransferase activity|glutamic--aspartic transaminase activity|oxaloacetate transferase activity|L-aspartate-2-oxoglutarate aminotransferase activity|transaminase A activity|aspartic aminotransferase activity|AAT|aspartate aminotransferase activity|L-aspartate-2-ketoglutarate aminotransferase activity|2-oxoglutarate-glutamate aminotransferase activity|glutamic-oxalacetic transaminase activity|glutamate oxaloacetate transaminase activity|L-aspartic aminotransferase activity|aspartate transaminase activity|glutamic--oxaloacetic transaminase activity|aspartate alpha-ketoglutarate transaminase activity|glutamate-oxalate transaminase activity|aspartate:2-oxoglutarate aminotransferase activity|L-aspartate-alpha-ketoglutarate transaminase activity|aspartyl aminotransferase activity|L-aspartate-2-oxoglutarate-transaminase activity|glutamic oxalic transaminase activity|glutamic-aspartic aminotransferase activity|AspT|GOT (enzyme)|glutamate-oxalacetate aminotransferase activity|aspartate-2-oxoglutarate transaminase activity				Reactome:R-HSA-70581|EC:2.6.1.1|Reactome:R-HSA-70592|KEGG_REACTION:R00355|Reactome:R-HSA-70613|Reactome:R-HSA-70596|MetaCyc:ASPAMINOTRANS-RXN|RHEA:21824									molecular_function											owl:Class	
GO:0072631	biolink:NamedThing	interleukin-29 production	The appearance of interleukin-29 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	tmpzr1t_l9r_go_relaxed.owl	IL29 production|IL-29 production|interleukin-29 secretion|interferon lambda 1 production					Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.						GO:0072632		biological_process											owl:Class	
GO:0002173	biolink:NamedThing	low-affinity IgM receptor activity	Combining with low affinity with an immunoglobulin of an IgM isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	low affinity IgM receptor activity							hjd	2010-05-06T05:04:24Z					molecular_function											owl:Class	
GO:0047716	biolink:NamedThing	imidazole N-acetyltransferase activity	Catalysis of the reaction: 1H-imidazole + acetyl-CoA = N-acetylimidazole + CoA.	tmpzr1t_l9r_go_relaxed.owl	imidazole acetylase activity|imidazole acetyltransferase activity|acetyl-CoA:imidazole N-acetyltransferase activity				RHEA:15813|KEGG_REACTION:R03621|MetaCyc:IMIDAZOLE-N-ACETYLTRANSFERASE-RXN|EC:2.3.1.2									molecular_function											owl:Class	
GO:0102334	biolink:NamedThing	N,N'-diacetylbacilliosaminyl-1-phosphate transferase activity	Catalysis of the reaction: ditrans,polycis-undecaprenyl phosphate + UDP-N,N'-diacetylbacillosamine <=> N,N'-diacetyl-alpha-D-bacillosaminyl-diphospho-tri-trans,hepta-cis-undecaprenol + UMP.	tmpzr1t_l9r_go_relaxed.owl					RHEA:34515|EC:2.7.8.36|MetaCyc:RXN-13269									molecular_function											owl:Class	
GO:0035577	biolink:NamedThing	azurophil granule membrane	The lipid bilayer surrounding an azurophil granule, a primary lysosomal granule found in neutrophil granulocytes that contains a wide range of hydrolytic enzymes and is released into the extracellular fluid.	tmpzr1t_l9r_go_relaxed.owl	primary granule membrane							bf	2010-10-05T01:29:10Z					cellular_component											owl:Class	
GO:0033434	biolink:NamedThing	AUC codon-amino acid adaptor activity	A triplet codon-amino acid adaptor activity that recognizes an AUC codon.	tmpzr1t_l9r_go_relaxed.owl	ATC codon-amino acid adaptor activity|isoleucine tRNA					Note that in the standard genetic code, ATC codes for isoleucine.								molecular_function											owl:Class	
GO:0018794	biolink:NamedThing	2-hydroxyisobutyrate decarboxylase activity	Catalysis of the reaction: 2-hydroxyisobutyrate + H+ = CO2 + 2-propanol.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0617									molecular_function											owl:Class	
GO:2001132	biolink:NamedThing	methane biosynthetic process from 3-(methylthio)propionic acid	The chemical reactions and pathways resulting in the formation of a methane from a 3-(methylthio)propionic acid.	tmpzr1t_l9r_go_relaxed.owl								jl	2011-10-13T12:19:33Z					biological_process											owl:Class	
GO:0050477	biolink:NamedThing	acyl-lysine deacylase activity	Catalysis of the reaction: H2O + N6-acyl-L-lysine = L-lysine + a carboxylate.	tmpzr1t_l9r_go_relaxed.owl	epsilon-lysine acylase activity|N6-acyl-L-lysine amidohydrolase activity|6-N-acyl-L-lysine amidohydrolase activity				MetaCyc:ACYL-LYSINE-DEACYLASE-RXN|EC:3.5.1.17|RHEA:24548									molecular_function											owl:Class	
GO:0018313	biolink:NamedThing	peptide cross-linking via L-alanyl-5-imidazolinone glycine	The formation of a protein active site cross-link from the alpha-carboxyl carbon of residue N, an alanine, to the alpha-amino nitrogen of residue N+2, a glycine, coupled with the formation of a double bond to the alpha-amino nitrogen of residue N+1 which loses one hydrogen, and the loss of a molecule of water.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0187									biological_process											owl:Class	
GO:0099176	biolink:NamedThing	regulation of retrograde trans-synaptic signaling by trans-synaptic protein complex	Any process that modulates the frequency, rate or extent of retrograde trans-synaptic signaling by a trans-synaptic complex.	tmpzr1t_l9r_go_relaxed.owl	regulation of trans-synaptic complex mediated retrograde trans-synaptic signaling													biological_process											owl:Class	
GO:0044495	biolink:NamedThing	modulation of blood pressure in other organism	A process by which one organism modulates the force with which blood travels through the circulatory system of another organism.	tmpzr1t_l9r_go_relaxed.owl	regulation of blood pressure in other organism							jl	2012-02-01T02:10:15Z					biological_process											owl:Class	
GO:0035728	biolink:NamedThing	response to hepatocyte growth factor	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hepatocyte growth factor stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to hepatocyte growth factor stimulus|response to HGF stimulus							bf	2011-03-10T03:02:47Z					biological_process											owl:Class	
GO:0048249	biolink:NamedThing	high-affinity phosphate transmembrane transporter activity	Enables the transfer of phosphate from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.	tmpzr1t_l9r_go_relaxed.owl	high affinity phosphate transmembrane transporter activity													molecular_function											owl:Class	
GO:0032685	biolink:NamedThing	negative regulation of granulocyte macrophage colony-stimulating factor production	Any process that stops, prevents, or reduces the frequency, rate, or extent of granulocyte macrophage colony-stimulating factor production.	tmpzr1t_l9r_go_relaxed.owl	down regulation of granulocyte macrophage colony-stimulating factor production|negative regulation of granulocyte macrophage colony-stimulating factor biosynthetic process|down-regulation of granulocyte macrophage colony-stimulating factor production|inhibition of granulocyte macrophage colony-stimulating factor production|negative regulation of GM-CSF production|downregulation of granulocyte macrophage colony-stimulating factor production|negative regulation of granulocyte macrophage colony stimulating factor production											GO:0045424		biological_process											owl:Class	
GO:0050633	biolink:NamedThing	acetyl-CoA C-myristoyltransferase activity	Catalysis of the reaction: myristoyl-CoA + acetyl-CoA = 3-oxopalmitoyl-CoA + CoA.	tmpzr1t_l9r_go_relaxed.owl	3-oxopalmitoyl-CoA-CoA acetyltransferase activity|myristoyl-CoA:acetyl-CoA C-myristoyltransferase activity|3-oxopalmitoyl-CoA hydrolase activity|myristoyl-CoA C-acetyltransferase activity				MetaCyc:2.3.1.155-RXN|EC:2.3.1.155|RHEA:18161									molecular_function											owl:Class	
GO:0043864	biolink:NamedThing	indoleacetamide hydrolase activity	Catalysis of the reaction: indole-3-acetamide + H2O = indole-3-acetate + NH3. Indole-3-acetamide is known as IAM and indole-3-acetate as IAA.	tmpzr1t_l9r_go_relaxed.owl	Tms2|IaaH|indole-3-acetamide hydrolase activity|indole acetamide hydrolase activity|IAH				EC:3.5.1.4|MetaCyc:G-5841|RHEA:34371									molecular_function											owl:Class	
GO:0039556	biolink:NamedThing	MDA-5 binding	Binding to MDA-5, a cytosolic pattern recognition receptor that initiates an antiviral signaling pathway upon binding to viral dsRNA.	tmpzr1t_l9r_go_relaxed.owl	MDA5 binding							bf	2012-03-09T04:12:33Z					molecular_function											owl:Class	
GO:0046600	biolink:NamedThing	negative regulation of centriole replication	Any process that stops, prevents, or reduces the frequency, rate or extent of centriole replication.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of centriole replication|inhibition of centriole replication|downregulation of centriole replication|down regulation of centriole replication													biological_process											owl:Class	
GO:0071979	biolink:NamedThing	cytoskeleton-mediated cell swimming	Cell motility in which contractile cytoskeletal elements alter cell shape, resulting in the smooth movement of a cell through a liquid medium.	tmpzr1t_l9r_go_relaxed.owl	cytoskeleton-mediated swimming motility							mah	2010-10-21T03:02:36Z					biological_process											owl:Class	
GO:2000019	biolink:NamedThing	negative regulation of male gonad development	Any process that stops, prevents, or reduces the frequency, rate or extent of male gonad development.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of testicular development|negative regulation of testis development							jl	2010-07-15T03:29:10Z					biological_process											owl:Class	
GO:0047631	biolink:NamedThing	ADP-ribose diphosphatase activity	Catalysis of the reaction: ADP-ribose + H2O = AMP + D-ribose 5-phosphate.	tmpzr1t_l9r_go_relaxed.owl	adenosine diphosphoribose pyrophosphatase activity|ADP-ribose pyrophosphatase activity|ADP-ribose ribophosphohydrolase activity|ADPribose pyrophosphatase activity|ADPR-PPase activity|ADPribose diphosphatase activity|ADP-ribose phosphohydrolase activity				RHEA:10412|Reactome:R-HSA-2393954|EC:3.6.1.13|Reactome:R-HSA-5696049|MetaCyc:RXN0-1441|Reactome:R-HSA-2393939									molecular_function											owl:Class	
GO:0030341	biolink:NamedThing	chondroitin AC lyase activity	Catalysis of the eliminative degradation of polysaccharides containing 1,4-beta-D-hexosaminyl and 1,3-beta-D-glucuronosyl linkages to disaccharides containing 4-deoxy-beta-D-gluc-4-enuronosyl groups.	tmpzr1t_l9r_go_relaxed.owl	chondroitin sulfate lyase activity|chondroitin lyase activity|ChnAC|chondroitinase activity|chondroitinase AC|chondroitin AC eliminase activity				MetaCyc:4.2.2.5-RXN|EC:4.2.2.5									molecular_function											owl:Class	
GO:0039641	biolink:NamedThing	viral inner membrane	The lipid bilayer of a virion contained inside the protein capsid.	tmpzr1t_l9r_go_relaxed.owl	virion inner membrane							bf	2012-09-07T13:29:48Z					cellular_component											owl:Class	
GO:0050637	biolink:NamedThing	lovastatin nonaketide synthase activity	Catalysis of the reaction: S-adenosyl-L-methionine(1+) + acetyl-CoA + 18 H(+) + 8 malonyl-CoA + 11 NADPH = S-adenosyl-L-homocysteine + 8 CO(2) + 9 CoA + dihydromonacolin L + 6 H(2)O + 11 NADP(+).	tmpzr1t_l9r_go_relaxed.owl	acyl-CoA:malonyl-CoA C-acyltransferase (decarboxylating, oxoacyl- and enoyl-reducing, thioester-hydrolysing)				KEGG_REACTION:R07251|MetaCyc:2.3.1.161-RXN|RHEA:18565|EC:2.3.1.161									molecular_function											owl:Class	
GO:0102532	biolink:NamedThing	genkwanin 6-hydroxylase activity	Catalysis of the reaction: genkwanin + O2 + NADPH + H+ <=> scutellarein 7-methyl ether + H2O + NADP.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-14748									molecular_function											owl:Class	
GO:2000713	biolink:NamedThing	negative regulation of maintenance of meiotic sister chromatid cohesion, arms	Any process that stops, prevents or reduces the frequency, rate or extent of maintenance of meiotic sister chromatid cohesion along the chromosome arms.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of maintenance of meiotic sister chromatin cohesion along arms|negative regulation of maintenance of sister chromatin cohesion along arms at meiosis I							mah	2011-06-01T12:45:39Z					biological_process											owl:Class	
GO:0038018	biolink:NamedThing	Wnt receptor catabolic process	The chemical reactions and pathways resulting in the breakdown of a Wnt receptor. Internalized Wnt receptors can be recycled to the plasma membrane or sorted to lysosomes for protein degradation.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of Wnt receptor signaling pathway by Wnt receptor degradation|Wnt receptor breakdown|Frizzled degradation|Wnt receptor catabolism|Wnt receptor degradation							bf	2011-06-23T04:38:12Z					biological_process											owl:Class	
GO:0021565	biolink:NamedThing	accessory nerve development	The process whose specific outcome is the progression of the accessory nerve over time, from its formation to the mature structure. In mice, the spinal branch of this motor nerve innervates the trapezius and the sternocleidomastoid muscles. The cranial branch joins the vagus nerve and innervates the same targets as the vagus nerve.	tmpzr1t_l9r_go_relaxed.owl	cranial nerve 11 development|spinal accessory nerve development|cranial nerve XI development|CN XI development													biological_process											owl:Class	
GO:0070154	biolink:NamedThing	mitochondrial lysyl-tRNA aminoacylation	The process of coupling lysine to lysyl-tRNA in a mitochondrion, catalyzed by lysyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0045436	biolink:NamedThing	lycopene beta cyclase activity	Catalysis of the cyclization of beta rings at one or both ends of the lycopene molecule (psi, psi-carotene) to form gamma-carotene or the bicyclic beta-carotene (beta, beta-carotene), respectively.	tmpzr1t_l9r_go_relaxed.owl	crtL|lycopene cyclase				MetaCyc:RXN1F-150|RHEA:32219									molecular_function											owl:Class	
GO:1990902	biolink:NamedThing	new cell pole	The cell pole proximal to the most recent cell division.	tmpzr1t_l9r_go_relaxed.owl								pr	2015-11-17T16:44:53Z					cellular_component											owl:Class	
GO:0021686	biolink:NamedThing	cerebellar granular layer maturation	A developmental process, independent of morphogenetic (shape) change, that is required for the cerebellar granular layer to attain its fully functional state. The granular layer is the innermost layer of the cerebellar cortex. This layer contains densely packed small neurons, mostly granule cells. Some Golgi cells are found at the outer border. Granule neurons send parallel fibers to the upper molecular layer, where they synapse with Purkinje cell dendrites. Mossy fibers from the pontine nuclei in the white matter synapse with granule cell axons, Golgi cell axons and unipolar brush interneuron axons at cerebellar glomeruli in the granule cell layer.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0030956	biolink:NamedThing	glutamyl-tRNA(Gln) amidotransferase complex	A protein complex that possesses glutamyl-tRNA(Gln) amidotransferase activity, and therefore creates Gln-tRNA by amidating Glu-tRNA; usually composed of 3 subunits: A, B, and C. Note that the C subunit may not be required in all organisms.	tmpzr1t_l9r_go_relaxed.owl	AdT|GatCAB|GatFAB					Note that this term represents a location and not a function; the activity possessed by this complex is mentioned in the definition for the purpose of describing and distinguishing the complex. The function possessed by this complex is represented by the molecular function term 'glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity ; GO:0050567'.								cellular_component											owl:Class	
GO:0022869	biolink:NamedThing	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity	Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + lactose(out) = protein histidine + lactose phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.	tmpzr1t_l9r_go_relaxed.owl	lactose PTS transporter activity													molecular_function											owl:Class	
GO:0043560	biolink:NamedThing	insulin receptor substrate binding	Binding to an insulin receptor substrate (IRS) protein, an adaptor protein that bind to the transphosphorylated insulin and insulin-like growth factor receptors, are themselves phosphorylated and in turn recruit SH2 domain-containing signaling molecules to form a productive signaling complex.	tmpzr1t_l9r_go_relaxed.owl	IRS binding|insulin receptor substrate [protein] binding|IRS [protein] binding													molecular_function											owl:Class	
GO:0050743	biolink:NamedThing	protein-FMN linkage via 1'-(8alpha-FMN)-L-histidine	The formation of a protein-FMN linkage via 1'-(8alpha-FMN)-L-histidine.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0352									biological_process											owl:Class	
GO:0120311	biolink:NamedThing	ciliary pro-basal body maturation	A process that is carried out at the cellular level which results in the conversion of an immature and partially assembled ciliary pro-basal body into a mature basal body that is capable of nucleating a cilium.	tmpzr1t_l9r_go_relaxed.owl	flagellar pro-basal body maturation|pro-basal body maturation|flagellar probasal body maturation							krc	2021-03-26T17:41:59Z					biological_process											owl:Class	
GO:1901427	biolink:NamedThing	response to propan-1-ol	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a propan-1-ol stimulus.	tmpzr1t_l9r_go_relaxed.owl								tt	2012-10-01T18:55:48Z					biological_process											owl:Class	
GO:1903962	biolink:NamedThing	arachidonate transmembrane transporter activity	Enables the transfer of arachidonate from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	arachidonate transporter activity|arachidonic acid transporter activity					An example of this is S100A9 in human (P06702) in PMID:15642721 (inferred from direct assay).		bhm	2015-02-25T15:51:12Z					molecular_function											owl:Class	
GO:0039642	biolink:NamedThing	virion nucleoid	The region of a virion in which the nucleic acid is confined.	tmpzr1t_l9r_go_relaxed.owl								bf	2012-09-07T14:14:52Z					cellular_component											owl:Class	
GO:0043816	biolink:NamedThing	phosphoserine-tRNA(Cys) ligase activity	Catalysis of the reaction: tRNA(Cys) + O-phospho-L-serine + ATP = AMP + diphosphate + phosphoseryl-tRNA(Cys).	tmpzr1t_l9r_go_relaxed.owl	phosphoserine-tRNACys ligase activity|O-phosphoseryl-tRNA(Cys) synthetase activity|phosphoserine--tRNA(Cys) ligase activity|SepRS				EC:6.1.1.27|RHEA:25678									molecular_function											owl:Class	
GO:0090663	biolink:NamedThing	galanin-activated signaling pathway	The series of molecular signals generated as a consequence of the peptide neurotransmitter galanin binding to a cell surface receptor.	tmpzr1t_l9r_go_relaxed.owl	galanin-activated signalling pathway|galanin signaling pathway|galanin signalling pathway							tb	2015-10-21T13:38:04Z					biological_process											owl:Class	
GO:0046682	biolink:NamedThing	response to cyclodiene	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cyclodiene stimulus. A cyclodiene is any organic insecticide (as dieldrin or chlordane) with a chlorinated methylene group forming a bridge across a 6-membered carbon ring.	tmpzr1t_l9r_go_relaxed.owl	cyclodiene resistance|cyclodiene susceptibility/resistance													biological_process											owl:Class	
GO:0036179	biolink:NamedThing	osteoclast maturation	A developmental process, independent of morphogenetic (shape) change, that is required for an osteoclast cell to attain its fully functional state. An osteoclast is a specialized phagocytic cell associated with the absorption and removal of the mineralized matrix of bone tissue, and which typically differentiates from monocytes.	tmpzr1t_l9r_go_relaxed.owl	chondroclast maturation							bf	2012-03-29T02:04:00Z					biological_process											owl:Class	
GO:0102453	biolink:NamedThing	anthocyanidin 3-O-glucoside 6''-O-acyltransferase activity	Catalysis of the reaction: 4-coumaryl-CoA + H+ + an anthocyanidin-3-O-beta-D-glucoside = coenzyme A + H+ + an anthocyanidin-3-O-[6-O-(hydroxycinnamoyl)-beta-D-glucoside].	tmpzr1t_l9r_go_relaxed.owl					RHEA:35411|EC:2.3.1.215|MetaCyc:RXN-13959									molecular_function											owl:Class	
GO:1990350	biolink:NamedThing	glucose transporter complex	A protein complex facilitating glucose transport into, out of or within a cell, or between cells.	tmpzr1t_l9r_go_relaxed.owl						An example of this is GTR1 in human (UniProt symbol P11166) in PMID:15449578 (inferred from direct assay).		bhm	2014-03-26T14:12:05Z					cellular_component											owl:Class	
GO:0002575	biolink:NamedThing	basophil chemotaxis	The movement of a basophil in response to an external stimulus.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0099540	biolink:NamedThing	trans-synaptic signaling by neuropeptide	Cell-cell signaling between presynapse and postsynapse mediated by a peptide ligand crossing the synaptic cleft.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0060397	biolink:NamedThing	growth hormone receptor signaling pathway via JAK-STAT	The process in which STAT proteins (Signal Transducers and Activators of Transcription) are activated by members of the JAK (janus activated kinase) family of tyrosine kinases, following the binding of physiological ligands to the growth hormone receptor. Once activated, STATs dimerize and translocate to the nucleus and modulate the expression of target genes.	tmpzr1t_l9r_go_relaxed.owl	JAK-STAT cascade involved in growth hormone signalling pathway													biological_process											owl:Class	
GO:0030604	biolink:NamedThing	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity	Catalysis of the reaction: 2-C-methyl-D-erythritol 4-phosphate + NADP(+) = 1-deoxy-D-xylulose 5-phosphate + H(+) + NADPH.	tmpzr1t_l9r_go_relaxed.owl	2-C-methyl-D-erythritol-4-phosphate:NADP+ oxidoreductase (isomerizing)|1-deoxyxylulose-5-phosphate reductoisomerase activity|2C-methyl-D-erythritol-4-phosphate (MEP) synthase activity|1-deoxy-D-xylulose-5-phosphate isomeroreductase activity|DOXP reductoisomerase activity|DXP-reductoisomerase activity				MetaCyc:DXPREDISOM-RXN|EC:1.1.1.267|KEGG_REACTION:R05688|RHEA:13717									molecular_function											owl:Class	
GO:0030197	biolink:NamedThing	extracellular matrix constituent, lubricant activity	Functions as a lubricant for an extracellular matrix, such as a mucous membrane.	tmpzr1t_l9r_go_relaxed.owl	core matrisome|core extracellular matrix					Extracellular matrix mucin proteins may be annotated to this term. PMID:14711375, PMID:18601586								molecular_function											owl:Class	
GO:0001647	biolink:NamedThing	G protein-coupled cytokinin receptor activity	Combining with cytokinin and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.	tmpzr1t_l9r_go_relaxed.owl	G protein coupled cytokinin receptor activity|cytokinin receptor activity, G-protein coupled|G-protein coupled cytokinin receptor activity													molecular_function											owl:Class	
GO:0106302	biolink:NamedThing	arachidonic acid 8,9-epoxygenase activity	Catalysis of an NADPH- and oxygen-dependent reaction that converts arachidonic acid to cis-8,9-epoxyeicosatrienoic acid.	tmpzr1t_l9r_go_relaxed.owl					RHEA:64984			hjd	2020-08-28T19:10:07Z					molecular_function											owl:Class	
GO:1904724	biolink:NamedThing	tertiary granule lumen	Any membrane-enclosed lumen that is part of a tertiary granule.	tmpzr1t_l9r_go_relaxed.owl	tertiary granule membrane-enclosed lumen|membrane-enclosed lumen of tertiary granule|gelatinase granule membrane-enclosed lumen|membrane-enclosed lumen of gelatinase granule							mec	2015-10-12T12:53:10Z					cellular_component											owl:Class	
GO:0047296	biolink:NamedThing	homospermidine synthase activity	Catalysis of the reaction: 2 putrescine = NH3 + sym-homospermidine.	tmpzr1t_l9r_go_relaxed.owl	putrescine:putrescine 4-aminobutyltransferase (ammonia-forming)				MetaCyc:2.5.1.44-RXN|EC:2.5.1.44|RHEA:18645									molecular_function											owl:Class	
GO:1905867	biolink:NamedThing	epididymis development	The process whose specific outcome is the progression of an epididymis over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl	epididymus development							sl	2017-01-27T00:00:33Z					biological_process											owl:Class	
GO:0002125	biolink:NamedThing	maternal aggressive behavior	Aggressive behavior of a female to protect her offspring from a threat.	tmpzr1t_l9r_go_relaxed.owl	maternal aggression					Paternal aggression also exists. Serves to protect the offspring from intruders.								biological_process											owl:Class	
GO:1900828	biolink:NamedThing	D-tyrosine metabolic process	The chemical reactions and pathways involving D-tyrosine.	tmpzr1t_l9r_go_relaxed.owl	D-tyrosine metabolism							se	2012-06-06T09:27:00Z					biological_process											owl:Class	
GO:0061342	biolink:NamedThing	regulation of cell adhesion involved in heart morphogenesis by non-canonical Wnt signaling pathway	Any process that decreased the extent of cell adhesion that contributes to the shaping of the heart.	tmpzr1t_l9r_go_relaxed.owl	regulation of cell adhesion involved in heart morphogenesis by non-canonical Wnt signalling pathway							dph	2010-09-29T11:30:15Z					biological_process											owl:Class	
GO:0102826	biolink:NamedThing	kaempferol-3-glucoside-glucosyltransferase activity	Catalysis of the reaction: UDP-alpha-D-glucose + kaempferol 3-O-glucoside <=> kaempferol 3,7-O-diglucoside + UDP.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-8270									molecular_function											owl:Class	
GO:0106294	biolink:NamedThing	NADPH oxidase H202-forming activity	Catalysis of the reaction: NADPH + H+ + O2 = NADP + hydrogen peroxide (H2O2).	tmpzr1t_l9r_go_relaxed.owl					RHEA:11260			hjd	2020-08-19T17:38:36Z					molecular_function											owl:Class	
GO:0061786	biolink:NamedThing	peptidoglycan stem peptide endopeptidase activity	A peptidoglycan endopeptidase activity that acts on a stem peptide of peptidoglycan.	tmpzr1t_l9r_go_relaxed.owl								dph	2016-09-07T16:47:04Z					molecular_function											owl:Class	
GO:0039643	biolink:NamedThing	host cell viral nucleoid	The region of a host cell that contains the viral genome.	tmpzr1t_l9r_go_relaxed.owl						To annotate the region of the complete virus particle in which the viral genome is contained, instead use 'virion nucleoid ; GO:0039642'.		bf	2012-09-07T15:41:18Z					cellular_component											owl:Class	
GO:0016235	biolink:NamedThing	aggresome	An inclusion body formed by dynein-dependent retrograde transport of an aggregated protein on microtubules.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Aggresome									cellular_component											owl:Class	
GO:0062072	biolink:NamedThing	H3K9me3 modified histone binding	Binding to a histone H3 in which the lysine residue at position 9 has been modified by trimethylation.	tmpzr1t_l9r_go_relaxed.owl								dph	2018-09-05T12:58:43Z					molecular_function											owl:Class	
GO:0071535	biolink:NamedThing	RING-like zinc finger domain binding	Binding to a RING-like zinc finger domain domain of a protein. The RING-like domain is a zinc finger domain that is related to the C3HC4 RING finger domain.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-01-08T03:10:14Z					molecular_function											owl:Class	
GO:1904021	biolink:NamedThing	negative regulation of G protein-coupled receptor internalization	Any process that stops, prevents or reduces the frequency, rate or extent of G protein-coupled receptor internalization.	tmpzr1t_l9r_go_relaxed.owl	inhibition of G-protein coupled receptor internalization|negative regulation of G-protein coupled receptor internalization|down-regulation of G-protein coupled receptor internalization|down regulation of G-protein coupled receptor internalization|downregulation of G-protein coupled receptor internalization							pga	2015-03-10T17:10:50Z					biological_process											owl:Class	
GO:0140122	biolink:NamedThing	regulation of Lewy body formation	Any process that modulates the frequency, rate or extent of Lewy body formation.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/14160						pg	2017-10-25T07:03:29Z					biological_process											owl:Class	
GO:1900804	biolink:NamedThing	brevianamide F catabolic process	The chemical reactions and pathways resulting in the breakdown of brevianamide F.	tmpzr1t_l9r_go_relaxed.owl	tryptophan-proline diketopiperazine catabolic process|L-prolyl-L-tryptophan anhydride breakdown|cyclo-L-tryptophanyl-L-proline catabolic process|cyclo-(Trp-Pro) degradation|L-tryptophyl-L-proline cyclic anhydride breakdown|cyclo-L-tryptophanyl-L-proline breakdown|brevianamide F catabolism|cyclo-L-Trp-L-Pro catabolism|tryptophan-proline diketopiperazine degradation|cyclo-L-Trp-L-Pro catabolic process|L-tryptophyl-L-proline cyclic anhydride catabolism|L-tryptophyl-L-proline cyclic anhydride catabolic process|cyclo-(Trp-Pro) catabolism|tryptophan-proline diketopiperazine catabolism|tryptophan-proline diketopiperazine breakdown|brevianamide F breakdown|cyclo-(Trp-Pro) catabolic process|L-prolyl-L-tryptophan anhydride catabolism|cyclo-L-Trp-L-Pro degradation|brevianamide F degradation|L-prolyl-L-tryptophan anhydride degradation|cyclo-L-tryptophanyl-L-proline degradation|cyclo-L-tryptophanyl-L-proline catabolism|L-tryptophyl-L-proline cyclic anhydride degradation|L-prolyl-L-tryptophan anhydride catabolic process|cyclo-L-Trp-L-Pro breakdown|cyclo-(Trp-Pro) breakdown							di	2012-06-04T09:52:41Z					biological_process											owl:Class	
GO:0106080	biolink:NamedThing	GATOR1 complex binding	Binding to a GATOR1 complex.	tmpzr1t_l9r_go_relaxed.owl								hjd	2017-12-22T14:49:54Z					molecular_function											owl:Class	
GO:0140644	biolink:NamedThing	neutrophil extracellular trap	Extracellular microbicidal structure composed of nuclear chromatin, histones and granular antimicrobial proteins. Histones and several neutrophil granule proteins associated with the DNA framework damage entrapped microorganisms.	tmpzr1t_l9r_go_relaxed.owl	NET	https://github.com/geneontology/go-ontology/issues/21416						pg	2021-05-12T07:03:05Z					cellular_component											owl:Class	
GO:0046761	biolink:NamedThing	viral budding from plasma membrane	A viral budding that starts with formation of a membrane curvature in the host plasma membrane.	tmpzr1t_l9r_go_relaxed.owl	viral budding from plasma membrane during viral capsid envelopment|virus budding from plasma membrane|plasma membrane viral budding|viral budding from plasma membrane by viral capsid envelopment|plasma membrane viral budding during viral capsid envelopment|virus budding from plasma membrane by viral capsid envelopment|virus budding from plasma membrane during viral capsid envelopment											GO:0046766|GO:0046767		biological_process											owl:Class	
GO:0035049	biolink:NamedThing	juvenile hormone acid methyltransferase activity	Catalysis of the transfer of a methyl group to juvenile hormone acid.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0061917	biolink:NamedThing	leading edge of dendritic growth cone	That part of the dendritic growth cone which represents the distal part of the structure.	tmpzr1t_l9r_go_relaxed.owl	dendritic growth cone leading edge|distal tip of dendritic growth cone							dph	2017-07-10T19:25:23Z					cellular_component											owl:Class	
GO:0071924	biolink:NamedThing	chemokine (C-C motif) ligand 22 production	The appearance of chemokine (C-C motif) ligand 22 (CCL22) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	tmpzr1t_l9r_go_relaxed.owl	CCL-22 production|C-C motif chemokine 22 production|CCL22 production							mah	2010-09-28T11:33:13Z					biological_process											owl:Class	
GO:0022842	biolink:NamedThing	narrow pore channel activity	Enables the transport of a solute across a membrane via a narrow pore channel that may be gated or ungated.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0047692	biolink:NamedThing	ATP deaminase activity	Catalysis of the reaction: ATP + H2O = ITP + NH3.	tmpzr1t_l9r_go_relaxed.owl	ATP aminohydrolase activity|adenosine triphosphate deaminase activity				MetaCyc:ATP-DEAMINASE-RXN|RHEA:13037|EC:3.5.4.18									molecular_function											owl:Class	
GO:0010471	biolink:NamedThing	GDP-galactose:mannose-1-phosphate guanylyltransferase activity	Catalysis of the reaction: GDP-L-galactose + alpha-D-mannose 1-phosphate = GDP-alpha-D-mannose + alpha-L-galactose-1-phosphate.	tmpzr1t_l9r_go_relaxed.owl	GDP-L-galactose phosphorylase activity|GDP-L-galactose:mannose-1-phosphate guanylyltransferase activity				MetaCyc:RXN4FS-12									molecular_function											owl:Class	
GO:0006370	biolink:NamedThing	7-methylguanosine mRNA capping	Addition of the 7-methylguanosine cap to the 5' end of a nascent messenger RNA transcript.	tmpzr1t_l9r_go_relaxed.owl	5' mRNA capping|5'-end processing|mRNA capping|5' end capping|5'-end mRNA processing													biological_process											owl:Class	
GO:0015528	biolink:NamedThing	lactose:proton symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: lactose(out) + H+(out) = lactose(in) + H+(in).	tmpzr1t_l9r_go_relaxed.owl	lactose:hydrogen symporter activity|lactose, galactose:hydrogen symporter activity													molecular_function											owl:Class	
GO:0018502	biolink:NamedThing	2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase activity	Catalysis of the reaction: 2,5-dichloro-2,5-cyclohexadiene-1,4-diol + NAD+ = NADH + H+ + 2,5-dichlorohydroquinone.	tmpzr1t_l9r_go_relaxed.owl					RHEA:15741|UM-BBD_reactionID:r0553|MetaCyc:LINC-RXN									molecular_function											owl:Class	
GO:0047377	biolink:NamedThing	5-(3,4-diacetoxybut-1-ynyl)-2,2'-bithiophene deacetylase activity	Catalysis of the reaction: 5-(3,4-diacetoxybut-1-ynyl)-2,2'-bithiophene + H(2)O = 5-(3-hydroxy-4-acetoxybut-1-ynyl)-2,2'-bithiophene + acetate + H(+).	tmpzr1t_l9r_go_relaxed.owl	5-(3,4-diacetoxybut-1-ynyl)-2,2'-bithiophene acetylhydrolase activity|3,4-diacetoxybutinylbithiophene:4-acetate esterase activity|diacetoxybutynylbithiophene acetate esterase activity				EC:3.1.1.66|KEGG_REACTION:R04525|MetaCyc:3.1.1.66-RXN|RHEA:16313									molecular_function											owl:Class	
GO:0008856	biolink:NamedThing	exodeoxyribonuclease X activity	Catalysis of the endonucleolytic cleavage of supercoiled plasma DNA to linear DNA duplexes.	tmpzr1t_l9r_go_relaxed.owl	Escherichia coli endodeoxyribonuclease activity|Escherichia coli endodeoxyribonuclease X activity|deoxyribonuclease X activity				MetaCyc:3.1.22.5-RXN|EC:3.1.11.-									molecular_function											owl:Class	
GO:0000243	biolink:NamedThing	commitment complex	A spliceosomal complex that is formed by association of the U1 snRNP with the 5' splice site of an unspliced intron in an RNA transcript.	tmpzr1t_l9r_go_relaxed.owl	mammalian spliceosomal E complex|mammalian spliceosomal complex E|yeast spliceosomal complex CC													cellular_component											owl:Class	
GO:0048811	biolink:NamedThing	male analia morphogenesis	The process in which the anatomical structures of the analia of the male are generated and organized. The analia is the posterior-most vertral appendage that develops from the genital disc.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0052653	biolink:NamedThing	3',5'-cyclic diguanylic acid metabolic process	The chemical reactions and pathways involving 3',5'-cyclic diguanylic acid, a cyclic purine dinucleotide in which the base groups are guanine.	tmpzr1t_l9r_go_relaxed.owl	cyclic diguanylate metabolic process|cdiGMP metabolism|cyclic diguanylate metabolism|cdiGMP metabolic process|3',5'-cyclic diguanylic acid metabolism							ai	2010-09-23T11:16:56Z					biological_process											owl:Class	
GO:0071114	biolink:NamedThing	alphaV-beta3 integrin-tumstatin complex	A protein complex that consists of an alphaV-beta3 integrin complex bound to tumstatin, the NC1 domain of the alpha3 chain of type IV collagen.	tmpzr1t_l9r_go_relaxed.owl	ITGAV-ITGB3-COL4A3 complex							mah	2009-11-13T02:18:29Z					cellular_component											owl:Class	
GO:0018278	biolink:NamedThing	N-terminal peptidyl-threonine deamination	The deamination of N-terminal peptidyl-threonine to form peptidyl-2-oxobutanoic acid.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0129									biological_process											owl:Class	
GO:0047856	biolink:NamedThing	dihydrocoumarin hydrolase activity	Catalysis of the reaction: 3,4-dihydrocoumarin + H(2)O = 3-(2-hydroxyphenyl)propanoate + H(+).	tmpzr1t_l9r_go_relaxed.owl	dihydrocoumarin lactonohydrolase activity|dihydrocoumarin lipase activity				KEGG_REACTION:R03692|EC:3.1.1.35|RHEA:10360|MetaCyc:DIHYDROCOUMARIN-LIPASE-RXN									molecular_function											owl:Class	
GO:0047779	biolink:NamedThing	citrate-CoA ligase activity	Catalysis of the reaction: ATP + citrate + CoA = (3S)-citryl-CoA + ADP + H(+) + phosphate.	tmpzr1t_l9r_go_relaxed.owl	citrate thiokinase activity|citrate:CoA ligase (ADP-forming)|citrate:CoA ligase activity|citryl-CoA synthetase activity				MetaCyc:CITRATE--COA-LIGASE-RXN|RHEA:21472|EC:6.2.1.18|KEGG_REACTION:R01322									molecular_function											owl:Class	
GO:0042567	biolink:NamedThing	insulin-like growth factor ternary complex	A complex of three proteins, which in animals is approximately 150kDa and consists of the insulin-like growth factor (IGF), the insulin-like growth factor binding protein-3 (IGFBP-3), or -5 (IGFBP-5) and an acid-labile subunit (ALS). The complex plays a role in growth and development.	tmpzr1t_l9r_go_relaxed.owl	IGF ternary complex													cellular_component											owl:Class	
GO:0030538	biolink:NamedThing	embryonic genitalia morphogenesis	The process, occurring in the embryo, by which the anatomical structures of the genitalia are generated and organized.	tmpzr1t_l9r_go_relaxed.owl	embryonic genital morphogenesis													biological_process											owl:Class	
GO:0102867	biolink:NamedThing	molybdenum cofactor sulfurtransferase activity	Catalysis of the reaction: 2 H+ + MoO2-molybdopterin cofactor(2-) + L-cysteine  <=> thio-molybdenum cofactor + L-alanine  + H2O.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-8351|EC:2.8.1.9|RHEA:42636									molecular_function											owl:Class	
GO:0034511	biolink:NamedThing	U3 snoRNA binding	Binding to a U3 small nucleolar RNA.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1903139	biolink:NamedThing	positive regulation of cell wall integrity MAPK cascade	Any process that activates or increases the frequency, rate or extent of MAPK cascade involved in cell wall organization or biogenesis.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of Slt2 cascade|up regulation of MAPK cascade involved in cell wall biogenesis|upregulation of PMK1-MAPK signal transduction pathway|upregulation of MAPKKK cascade involved in cell wall biogenesis|up-regulation of cell integrity MAPK pathway|upregulation of Pmk1 MAPK cell integrity signaling|positive regulation of Slt2 cascade|positive regulation of Mpk1 cascade|up regulation of cell integrity MAPK pathway|positive regulation of MAPKKK cascade involved in cell wall biogenesis|activation of cell integrity MAPK pathway|upregulation of cell integrity MAPK pathway|activation of Slt2 cascade|positive regulation of Pmk1 MAPK cell integrity signaling|up regulation of PMK1-MAPK signal transduction pathway|up-regulation of MAPK cascade involved in cell wall organization or biogenesis|up regulation of Mpk1 cascade|up regulation of Slt2 cascade|up regulation of Pmk1 MAPK cell integrity signaling|positive regulation of cell integrity MAPK pathway|upregulation of Pmk1 mitogen-activated protein kinase (MAPK) cell integrity pathway|upregulation of MAPK cascade involved in cell wall biogenesis|activation of MAPK cascade involved in cell wall organization or biogenesis|up-regulation of MAPKKK cascade involved in cell wall biogenesis|upregulation of MAPK cascade involved in cell wall organization or biogenesis|positive regulation of cell wall biogenesis, MAPKKK cascade|up-regulation of cell wall biogenesis, MAPKKK cascade|up-regulation of Pmk1 MAPK cell integrity signaling|activation of Pmk1 mitogen-activated protein kinase (MAPK) cell integrity pathway|positive regulation of MAPK cascade involved in cell wall organization or biogenesis|activation of MAPKKK cascade involved in cell wall biogenesis|up-regulation of PMK1-MAPK signal transduction pathway|activation of cell wall biogenesis, MAPKKK cascade|activation of Mpk1 cascade|activation of MAPK cascade involved in cell wall biogenesis|upregulation of Slt2 cascade|up-regulation of Mpk1 cascade|up regulation of MAPKKK cascade involved in cell wall biogenesis|activation of Pmk1 MAPK cell integrity signaling|upregulation of Mpk1 cascade|up regulation of MAPK cascade involved in cell wall organization or biogenesis|up-regulation of MAPK cascade involved in cell wall biogenesis|up regulation of Pmk1 mitogen-activated protein kinase (MAPK) cell integrity pathway|positive regulation of Pmk1 mitogen-activated protein kinase (MAPK) cell integrity pathway|upregulation of cell wall biogenesis, MAPKKK cascade|positive regulation of PMK1-MAPK signal transduction pathway|activation of PMK1-MAPK signal transduction pathway|positive regulation of MAPK cascade involved in cell wall biogenesis|up-regulation of Pmk1 mitogen-activated protein kinase (MAPK) cell integrity pathway|up regulation of cell wall biogenesis, MAPKKK cascade	https://github.com/geneontology/go-ontology/issues/20131						mah	2014-07-01T10:22:05Z					biological_process											owl:Class	
GO:0005199	biolink:NamedThing	structural constituent of cell wall	The action of a molecule that contributes to the structural integrity of a cell wall.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0102947	biolink:NamedThing	(+)-delta-cadinene-8-hydroxylase activity	Catalysis of the reaction: H+ + (+)-delta-cadinene + NADPH + O2 <=> 8-hydroxy-(+)-delta-cadinene + NADP + H2O.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-9045									molecular_function											owl:Class	
GO:0120165	biolink:NamedThing	perithecium development	The process whose specific outcome is the progression of a perithecium over time, from its formation to the mature structure. Peritheicum is a flask-shaped fruiting body of certain molds and ascomycetous fungi having a pore for the escape of spores. In the ascomycetous fungi such as Neurospora crassa and Sordaria macrospora, these perithecia are formed in the sexual phase and they discharge ascospores through the ostiolum at the tip of the perithecial neck.	tmpzr1t_l9r_go_relaxed.owl								krc	2018-05-17T17:17:44Z					biological_process											owl:Class	
GO:0050323	biolink:NamedThing	taurine dehydrogenase activity	Catalysis of the reaction: A + H(2)O + taurine = AH(2) + NH(4)(+) + sulfoacetaldehyde.	tmpzr1t_l9r_go_relaxed.owl	taurine:(acceptor) oxidoreductase (deaminating)|taurine:acceptor oxidoreductase (deaminating)				EC:1.4.99.2|RHEA:18709|KEGG_REACTION:R07167|MetaCyc:TAURINE-DEHYDROGENASE-RXN									molecular_function											owl:Class	
GO:0120047	biolink:NamedThing	positive regulation of protein localization to medial cortical node	Any process that activates or increases the frequency, rate or extent of protein localization to a medial cortical node.	tmpzr1t_l9r_go_relaxed.owl								krc	2017-06-02T17:30:38Z					biological_process											owl:Class	
GO:0008272	biolink:NamedThing	sulfate transport	The directed movement of sulfate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	sulphate transport											GO:0006870		biological_process											owl:Class	
GO:0001193	biolink:NamedThing	maintenance of transcriptional fidelity during DNA-templated transcription elongation from RNA polymerase II promoter	Suppression of the occurrence of transcriptional errors, such as substitutions and/or insertions of nucleotides that do not correctly match the template base, during the process of transcription elongation from an RNA polymerase II promoter.	tmpzr1t_l9r_go_relaxed.owl	maintenance of transcriptional fidelity during DNA-dependent transcription elongation from RNA polymerase II promoter							krc	2011-09-02T02:31:00Z					biological_process											owl:Class	
GO:1902518	biolink:NamedThing	response to cyclophosphamide	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cyclophosphamide stimulus.	tmpzr1t_l9r_go_relaxed.owl						Note that this term is in the subset of terms that should not be used for direct manual annotation of gene products. It was created to be used for cross-referencing by other ontologies. Direct annotations to this term may be amended during annotation QC.		dw	2013-12-02T09:34:08Z					biological_process											owl:Class	
GO:0103075	biolink:NamedThing	indole-3-pyruvate monooxygenase activity	Catalysis of the reaction: 3-(indol-3-yl)pyruvate + NADPH + O2 + H+ <=> indole-3-acetate + carbon dioxide + NADP + H2O.	tmpzr1t_l9r_go_relaxed.owl					RHEA:34331|MetaCyc:RXNDQC-2|EC:1.14.13.168									molecular_function											owl:Class	
GO:0003866	biolink:NamedThing	3-phosphoshikimate 1-carboxyvinyltransferase activity	Catalysis of the reaction: 3-phosphoshikimate + phosphoenolpyruvate = 5-O-(1-carboxyvinyl)-3-phosphoshikimate + phosphate.	tmpzr1t_l9r_go_relaxed.owl	phosphoenolpyruvate:3-phosphoshikimate 5-O-(1-carboxyvinyl)-transferase activity|5-enolpyruvylshikimate-3-phosphate synthase activity|EPSP synthase activity|3-enol-pyruvoylshikimate-5-phosphate synthase activity				EC:2.5.1.19|KEGG_REACTION:R03460|MetaCyc:2.5.1.19-RXN|RHEA:21256									molecular_function											owl:Class	
GO:0018661	biolink:NamedThing	orcinol 2-monooxygenase activity	Catalysis of the reaction: H(+) + NADH + O(2) + orcinol = 2,3,5-trihydroxytoluene + H(2)O + NAD(+).	tmpzr1t_l9r_go_relaxed.owl	orcinol,NADH:oxygen oxidoreductase (2-hydroxylating)|orcinol hydroxylase activity				MetaCyc:ORCINOL-2-MONOOXYGENASE-RXN|RHEA:19601|EC:1.14.13.6|UM-BBD_reactionID:r0092|KEGG_REACTION:R02830									molecular_function											owl:Class	
GO:0140343	biolink:NamedThing	phosphatidylserine transfer activity	Removes phosphatidylserine from the outer leaflet of a donor membrane, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to the outer leaflet of an acceptor membrane.	tmpzr1t_l9r_go_relaxed.owl	intermembrane phosphatidylserine carrier activity							pg	2019-05-16T11:46:19Z					molecular_function											owl:Class	
GO:0070313	biolink:NamedThing	RGS6-DNMT1-DMAP1 complex	A protein complex formed by the association of RGS6, a negative regulator of heterotrimeric G protein signaling, with the DMAP1-Dnmt1 transcriptional repressor complex; in the complex, RGS6 inhibits the transcriptional repressor activity of DMAP1.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:1905642	biolink:NamedThing	negative regulation of DNA methylation	Any process that stops, prevents or reduces the frequency, rate or extent of DNA methylation.	tmpzr1t_l9r_go_relaxed.owl	down regulation of DNA methylation|inhibition of DNA methylation|downregulation of DNA methylation|down-regulation of DNA methylation							bc	2016-11-04T16:43:13Z					biological_process											owl:Class	
GO:0047538	biolink:NamedThing	2-carboxy-D-arabinitol-1-phosphatase activity	Catalysis of the reaction: 2-carboxy-D-arabinitol 1-phosphate + H(2)O = 2-carboxy-D-arabinitol + phosphate.	tmpzr1t_l9r_go_relaxed.owl	2-carboxy-D-arabinitol 1-phosphate phosphohydrolase activity|2-carboxy-D-arabinitol-1-phosphate 1-phosphohydrolase activity|2-carboxyarabinitol 1-phosphatase activity				RHEA:17837|MetaCyc:2-CARBOXY-D-ARABINITOL-1-PHOSPHATASE-RXN|EC:3.1.3.63|KEGG_REACTION:R04167									molecular_function											owl:Class	
GO:0021599	biolink:NamedThing	abducens nerve formation	The process that gives rise to the abducens nerve. This process pertains to the initial formation of a structure from unspecified parts. The motor function of the abducens nerve is to contract the lateral rectus which results in abduction of the eye.	tmpzr1t_l9r_go_relaxed.owl	CN VI formation|CN VI biosynthesis													biological_process											owl:Class	
GO:0042468	biolink:NamedThing	klinokinesis	The movement of a cell or organism in response to a stimulus in which the frequency or magnitude of turning behavior is altered.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1990624	biolink:NamedThing	guanyl nucleotide exchange factor inhibitor activity	Binds to and stops, prevents or reduces the activity of a guanyl nucleotide exchange factor.	tmpzr1t_l9r_go_relaxed.owl								vw	2015-01-31T15:17:01Z					molecular_function											owl:Class	
GO:0046523	biolink:NamedThing	S-methyl-5-thioribose-1-phosphate isomerase activity	Catalysis of the reaction: S-methyl-5-thio-alpha-D-ribose 1-phosphate = S-methyl-5-thio-D-ribulose 1-phosphate.	tmpzr1t_l9r_go_relaxed.owl	S-methyl-5-thio-alpha-D-ribose-1-phosphate aldose-ketose-isomerase activity|1-phospho-5'-S-methylthioribose isomerase activity|methylthioribose 1-phosphate isomerase activity|S-methyl-5-thio-5-deoxy-D-ribose-1-phosphate ketol-isomerase activity|5-methylthioribose-1-phosphate isomerase activity|MTR-1-P isomerase activity|S-methyl-5-thio-D-ribose-1-phosphate aldose-ketose-isomerase activity|S-methyl-5-thio-5-deoxy-D-ribose-1-phosphate aldose-ketose-isomerase activity|1-PMTR isomerase activity|5-methylthio-5-deoxy-D-ribose-1-phosphate ketol-isomerase activity				MetaCyc:5.3.1.23-RXN|Reactome:R-HSA-1299507|Reactome:R-HSA-1237096|RHEA:19989|KEGG_REACTION:R04420|EC:5.3.1.23									molecular_function											owl:Class	
GO:0072571	biolink:NamedThing	mono-ADP-D-ribose binding	Binding to monomeric ADP-D-ribose, an ADP-aldose having ribose as the aldose fragment.	tmpzr1t_l9r_go_relaxed.owl	mono-ADP-ribose binding|mADPr binding							mah	2011-01-31T02:39:12Z					molecular_function											owl:Class	
GO:0032799	biolink:NamedThing	low-density lipoprotein receptor particle metabolic process	The chemical reactions and pathways involving low-density lipoprotein receptors.	tmpzr1t_l9r_go_relaxed.owl	low-density lipoprotein receptor metabolic process|low-density lipoprotein receptor metabolism|LDL receptor metabolic process													biological_process											owl:Class	
GO:1905633	biolink:NamedThing	establishment of protein localization to euchromatin	The directed movement of a protein to a specific location in an euchromatin.	tmpzr1t_l9r_go_relaxed.owl	establishment of protein localisation in euchromatin|establishment of protein localization in euchromatin|establishment of protein localisation to euchromatin							pga	2016-11-01T16:16:22Z					biological_process											owl:Class	
GO:1905632	biolink:NamedThing	protein localization to euchromatin	A process in which a protein is transported to, or maintained in, a location within an euchromatin.	tmpzr1t_l9r_go_relaxed.owl	protein localization in euchromatin|protein localisation in euchromatin|protein localisation to euchromatin							pga	2016-11-01T16:16:14Z					biological_process											owl:Class	
GO:0110113	biolink:NamedThing	positive regulation of lipid transporter activity	Any process that increases the frequency, rate, or extent of lipid transporter activity.	tmpzr1t_l9r_go_relaxed.owl								kmv	2018-07-06T19:14:13Z					biological_process											owl:Class	
GO:0050568	biolink:NamedThing	protein-glutamine glutaminase activity	Catalysis of the reaction: protein L-glutamine + H2O = protein L-glutamate + NH3.	tmpzr1t_l9r_go_relaxed.owl	peptidylglutaminase II|glutaminylpeptide glutaminase activity|destabilase activity|peptidoglutaminase II activity|protein-L-glutamine amidohydrolase activity|glutaminyl-peptide glutaminase activity				EC:3.5.1.44|RHEA:16441|MetaCyc:CHEBDEAMID-RXN									molecular_function											owl:Class	
GO:0061148	biolink:NamedThing	extracellular matrix organization involved in endocardium development	A process which results in the assembly, arrangement of constituent parts, or disassembly of an extracellular matrix of the endocardium. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers.	tmpzr1t_l9r_go_relaxed.owl	extracellular matrix organisation involved in endocardium development							dph	2010-06-03T09:18:02Z					biological_process											owl:Class	
GO:0033499	biolink:NamedThing	galactose catabolic process via UDP-galactose	The chemical reactions and pathways resulting in the breakdown of galactose, via the intermediate UDP-galactose.	tmpzr1t_l9r_go_relaxed.owl	galactose catabolism via UDP-galactose|galactose breakdown via UDP-galactose|Leloir Pathway|galactose degradation via UDP-galactose				MetaCyc:PWY-3821									biological_process											owl:Class	
GO:0005128	biolink:NamedThing	erythropoietin receptor binding	Binding to an erythropoietin receptor.	tmpzr1t_l9r_go_relaxed.owl	erythropoietin|erythropoietin receptor ligand													molecular_function											owl:Class	
GO:0050264	biolink:NamedThing	rifamycin-B oxidase activity	Catalysis of the reaction: 2 H(+) + O(2) + rifamycin B = H(2)O(2) + rifamycin O.	tmpzr1t_l9r_go_relaxed.owl	rifamycin B oxidase activity|rifamycin-B:oxygen oxidoreductase activity|rifamycin-B-oxidase activity				KEGG_REACTION:R03736|MetaCyc:RIFAMYCIN-B-OXIDASE-RXN|RHEA:11292|EC:1.10.3.6									molecular_function											owl:Class	
GO:0021739	biolink:NamedThing	mesencephalic trigeminal nucleus development	The process whose specific outcome is the progression of the mesencephalic trigeminal nucleus over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0047848	biolink:NamedThing	dephospho-[reductase kinase] kinase activity	Catalysis of the reaction: ATP + dephospho-[[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase] = ADP + [[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase].	tmpzr1t_l9r_go_relaxed.owl	reductase kinase activity|AMP-activated protein kinase kinase activity|hydroxymethylglutaryl coenzyme A reductase kinase kinase activity|dephospho-reductase kinase kinase activity|hydroxymethylglutaryl coenzyme A reductase kinase kinase (phosphorylating) activity|AMP-activated kinase activity|STK30|ATP:dephospho-{hydroxymethylglutaryl-CoA reductase (NADPH)kinase} phosphotransferase activity|reductase kinase kinase activity				EC:2.7.11.3|MetaCyc:DEPHOSPHO-REDUCTASE-KINASE-KINASE-RXN									molecular_function											owl:Class	
GO:0052924	biolink:NamedThing	all-trans-nonaprenyl-diphosphate synthase (geranylgeranyl-diphosphate specific) activity	Catalysis of the reaction: geranylgeranyl diphosphate + 5 isopentenyl diphosphate = 5 diphosphate + all-trans-nonaprenyl diphosphate.	tmpzr1t_l9r_go_relaxed.owl	nonaprenyl diphosphate synthase activity|solanesyl diphosphate synthetase activity|solanesyl diphosphate synthase activity				KEGG_REACTION:R09251|RHEA:27594|MetaCyc:RXN-11486|EC:2.5.1.85									molecular_function											owl:Class	
GO:0004794	biolink:NamedThing	L-threonine ammonia-lyase activity	Catalysis of the reaction: L-threonine = 2-oxobutanoate + NH3.	tmpzr1t_l9r_go_relaxed.owl	threonine dehydrase activity|L-threonine hydro-lyase (deaminating) activity|L-threonine deaminase activity|L-threonine dehydratase activity|threonine dehydratase activity|threonine deaminase activity|serine deaminase activity|threonine ammonia-lyase activity|L-threonine ammonia-lyase (2-oxobutanoate-forming)|L-serine dehydratase activity				UM-BBD_reactionID:r0433|EC:4.3.1.19|RHEA:22108|MetaCyc:THREDEHYD-RXN	Note that this function was formerly EC:4.2.1.16.								molecular_function											owl:Class	
GO:0030796	biolink:NamedThing	cycloartenol 24-C-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + cycloartenol = (24R)-24-methylcycloart-25-en-3beta-ol + S-adenosyl-L-homocysteine + H(+).	tmpzr1t_l9r_go_relaxed.owl	S-adenosyl-L-methionine:cycloartenol 24-C-methyltransferase activity|sterol C-methyltransferase activity				EC:2.1.1.142|RHEA:13137|MetaCyc:2.1.1.142-RXN|KEGG_REACTION:R05760									molecular_function											owl:Class	
GO:0051909	biolink:NamedThing	acetylenecarboxylate hydratase activity, producing 3-hydroxypropenoate	Catalysis of the reaction: 3-hydroxypropenoate = propynoate + H2O.	tmpzr1t_l9r_go_relaxed.owl	acetylenecarboxylate hydratase activity|acetylenemonocarboxylate hydratase activity|3-hydroxypropenoate dehydratase activity|alkynoate hydratase activity				EC:4.2.1.27									molecular_function											owl:Class	
GO:0086076	biolink:NamedThing	gap junction channel activity involved in atrial cardiac muscle cell-AV node cell electrical coupling	A wide pore channel activity that enables a direct cytoplasmic connection from an atrial cardiomyocyte to an AV node cell. The gap junction passes electrical signals between the cells contributing to cardiac conduction.	tmpzr1t_l9r_go_relaxed.owl	gap junction channel activity involved in atrial cardiomyocyte-atrioventricular node cell electrical coupling|gap junction channel activity involved in atrial cardiomyocyte-AV node cell electrical coupling							dph	2011-11-22T10:26:27Z					molecular_function											owl:Class	
GO:0019680	biolink:NamedThing	L-methylmalonyl-CoA biosynthetic process	The chemical reactions and pathways resulting in the formation of L-methylmalonyl-CoA, the L-enantiomer of 2-carboxypropanoyl-CoA.	tmpzr1t_l9r_go_relaxed.owl	L-methylmalonyl-CoA formation|L-methylmalonyl-CoA anabolism|L-methylmalonyl-CoA biosynthesis|L-methylmalonyl-CoA synthesis				MetaCyc:PWY0-43									biological_process											owl:Class	
GO:0062102	biolink:NamedThing	female germline stem cell symmetric division	Division of a female germline stem cell to produce two germline stem cells of the same type as the parent.	tmpzr1t_l9r_go_relaxed.owl								dph	2018-12-18T14:17:54Z					biological_process											owl:Class	
GO:1905233	biolink:NamedThing	response to codeine	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a codeine stimulus.	tmpzr1t_l9r_go_relaxed.owl								sl	2016-06-07T21:26:45Z					biological_process											owl:Class	
GO:0007524	biolink:NamedThing	adult visceral muscle development	The process whose specific outcome is the progression of the adult visceral muscle over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0033414	biolink:NamedThing	UGC codon-amino acid adaptor activity	A triplet codon-amino acid adaptor activity that recognizes a UGC codon.	tmpzr1t_l9r_go_relaxed.owl	cysteine tRNA|TGC codon-amino acid adaptor activity					Note that in the standard genetic code, TGC codes for cysteine.								molecular_function											owl:Class	
GO:0120073	biolink:NamedThing	negative regulation of pyloric antrum smooth muscle contraction	Any process that decreases the frequency, rate or extent of any pyloric antrum smooth muscle contraction.	tmpzr1t_l9r_go_relaxed.owl								krc	2017-06-13T23:33:11Z					biological_process											owl:Class	
GO:0005041	biolink:NamedThing	low-density lipoprotein particle receptor activity	Combining with a low-density lipoprotein particle and delivering the low-density lipoprotein particle into the cell via endocytosis.	tmpzr1t_l9r_go_relaxed.owl	low-density lipoprotein receptor activity|LDLR activity|LDL receptor				Wikipedia:LDL_receptor|Reactome:R-HSA-2404131|Reactome:R-HSA-2424254							GO:0008032		molecular_function											owl:Class	
GO:0034206	biolink:NamedThing	enhanceosome	A protein-DNA complex formed by the association of a distinct set of general and specific transcription factors with a region of enhancer DNA. The cooperative assembly of an enhanceosome confers specificity of transcriptional regulation.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Enhanceosome									cellular_component											owl:Class	
GO:0032793	biolink:NamedThing	positive regulation of CREB transcription factor activity	Any process that activates or increases the frequency, rate or extent of activity of the transcription factor CREB.	tmpzr1t_l9r_go_relaxed.owl	activation of CREB transcription factor|activation of CREB|CREB activator													biological_process											owl:Class	
GO:0080113	biolink:NamedThing	regulation of seed growth	Any process that modulates the frequency, rate or extent of growth of the seed of an plant.	tmpzr1t_l9r_go_relaxed.owl	regulation of seed size							dhl	2009-04-27T02:55:01Z					biological_process											owl:Class	
GO:0008113	biolink:NamedThing	peptide-methionine (S)-S-oxide reductase activity	Catalysis of the reactions: peptide-L-methionine + thioredoxin disulfide + H2O = peptide-L-methionine (S)-S-oxide + thioredoxin, and L-methionine + thioredoxin disulfide + H2O = L-methionine (S)-S-oxide + thioredoxin. Can act on oxidized methionine in peptide linkage with specificity for the S enantiomer. Thioredoxin disulfide is the oxidized form of thioredoxin.	tmpzr1t_l9r_go_relaxed.owl	methionine S-oxide reductase activity|peptide methionine sulfoxide reductase activity|methionine sulfoxide reductase A activity|methionine sulfoxide (protein) reductase activity|peptide-L-methionine:thioredoxin-disulfide S-oxidoreductase [L-methionine (S)-S-oxide-forming] activity|peptide-methionine-(S)-S-oxide reductase activity|MsrA|methionine sulphoxide reductase A activity|methionine sulfoxide reductase activity|protein-methionine-S-oxide reductase activity|methionine S-oxide reductase (S-form oxidizing) activity|peptide Met(O) reductase activity				EC:1.8.4.11|Reactome:R-HSA-1222363|RHEA:14217|MetaCyc:RXN-8669|Reactome:R-HSA-5676940|MetaCyc:RXN-8668							GO:0072561|GO:0033742		molecular_function											owl:Class	
GO:0015191	biolink:NamedThing	L-methionine transmembrane transporter activity	Enables the transfer of L-methionine from one side of a membrane to the other. L-methionine is 2-amino-4-(methylthio)butanoic acid.	tmpzr1t_l9r_go_relaxed.owl	L-methionine transporter activity													molecular_function											owl:Class	
GO:0021972	biolink:NamedThing	corticospinal neuron axon guidance through spinal cord	The process in which the migration of an axon growth cone of a pyramidal cell that is part of the corticospinal tract is directed after decussation through the spinal cord in response to a combination of attractive and repulsive cues.	tmpzr1t_l9r_go_relaxed.owl	corticospinal neuron axon pathfinding through spinal cord													biological_process											owl:Class	
GO:0030963	biolink:NamedThing	peptidyl-lysine dihydroxylation to 4,5-dihydroxy-L-lysine	The dihydroxylation of peptidyl-lysine to peptidyl-4,5-dihydroxy-L-lysine.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0370									biological_process											owl:Class	
GO:0000053	biolink:NamedThing	argininosuccinate metabolic process	The chemical reactions and pathways involving argininosuccinate, 2-(N(omega)-arginino)succinate, an intermediate in the ornithine-urea cycle, where it is synthesized from citrulline and aspartate.	tmpzr1t_l9r_go_relaxed.owl	argininosuccinate metabolism													biological_process											owl:Class	
GO:0033486	biolink:NamedThing	delphinidin 3-O-glucoside biosynthetic process	The chemical reactions and pathways resulting in the formation of delphinidin 3-O-glucoside, a basic, water-soluble anthocyanin responsible for blue coloration of flowers and fruits.	tmpzr1t_l9r_go_relaxed.owl	delphinidin 3-O-glucoside anabolism|delphinidin 3-O-glucoside synthesis|delphinidin 3-O-glucoside formation|delphinidin 3-O-glucoside biosynthesis				MetaCyc:PWY-5153									biological_process											owl:Class	
GO:0043912	biolink:NamedThing	D-lysine oxidase activity	Catalysis of the reaction: D-lysine + O2 + H2O = 6-amino-2-oxohexanoate + NH3 + hydrogen peroxide.	tmpzr1t_l9r_go_relaxed.owl					EC:1.4.3.-									molecular_function											owl:Class	
GO:0034906	biolink:NamedThing	N-isopropylaniline 1,2-dixoxygenase activity	Catalysis of the reaction: N-isopropylaniline + O2 + 2 H+ + NADH = catechol + NAD+ + isopropylamine.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0721|EC:1.14.12.-									molecular_function											owl:Class	
GO:0047065	biolink:NamedThing	sulochrin oxidase [(-)-bisdechlorogeodin-forming] activity	Catalysis of the reaction: O(2) + 2 sulochrin = 2 (2R)-bisdechlorogeodin + 2 H(2)O.	tmpzr1t_l9r_go_relaxed.owl	sulochrin oxidase activity|sulochrin:oxygen oxidoreductase (cyclizing, (-)-specific)				MetaCyc:1.10.3.8-RXN|RHEA:22616|KEGG_REACTION:R00061|EC:1.21.3.5									molecular_function											owl:Class	
GO:0010773	biolink:NamedThing	meiotic DNA recombinase assembly involved in meiotic gene conversion	The aggregation, arrangement and bonding together of strand exchange proteins (recombinases) to form higher order oligomers on single-stranded DNA resulting in meiotic gene conversion. Meiotic gene conversion is the cell cycle process in which genetic information is transferred from one helix to another.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0051923	biolink:NamedThing	sulfation	The addition of a sulfate group to a molecule.	tmpzr1t_l9r_go_relaxed.owl	sulfonation|phase II metabolism|sulphation|sulfur addition|sulphur addition													biological_process											owl:Class	
GO:0070080	biolink:NamedThing	titin Z domain binding	Binding to a titin Z protein domain, which recognizes and binds to the C-terminal calmodulin-like domain of alpha-actinin-2 (Act-EF34), adopts a helical structure, and binds in a groove formed by the two planes between the helix pairs of Act-EF34.	tmpzr1t_l9r_go_relaxed.owl	Z repeat domain binding													molecular_function											owl:Class	
GO:2000253	biolink:NamedThing	positive regulation of feeding behavior	Any process that activates or increases the frequency, rate or extent of feeding behavior.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of drinking|positive regulation of feeding behaviour|positive regulation of behavioral response to food|positive regulation of behavioural response to food|positive regulation of eating							yaf	2010-11-18T11:24:18Z					biological_process											owl:Class	
GO:0030369	biolink:NamedThing	ICAM-3 receptor activity	Combining with ICAM-3, intercellular adhesion molecule 3, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. ICAM-3, or CD50, are constitutively expressed on monocytes, granulocytes and lymphocytes; on physiological stimulation, they become transiently phosphorylated on serine residues.	tmpzr1t_l9r_go_relaxed.owl						Note that this term represents an activity and not a gene product. Consider also annotating to the molecular function terms 'cell adhesion molecule binding ; GO:0050839' and 'receptor binding ; GO:0005102' and the biological process term 'cell adhesion ; GO:0007155'.								molecular_function											owl:Class	
GO:0102793	biolink:NamedThing	soyasapogenol B glucuronosyltransferase activity	Catalysis of the reaction: UDP-alpha-D-glucuronate + soyasapogenol B <=> H+ + UDP + soyasapogenol B 3-O-beta-glucuronate.	tmpzr1t_l9r_go_relaxed.owl					EC:2.4.1.262|MetaCyc:RXN-8086|RHEA:31475									molecular_function											owl:Class	
GO:0009655	biolink:NamedThing	PSII associated light-harvesting complex II, core complex	The pigment-protein complex primarily associated to PSII in higher plants, green algae and cyanobacteria that directly transfers electrons to the reaction center.	tmpzr1t_l9r_go_relaxed.owl	PSII associated light-harvesting complex II, core complex, LHCIIa subcomplex|PSII associated light-harvesting complex II, core complex, LHCIIc subcomplex|PSII associated light-harvesting complex II, core complex, LHCIId subcomplex													cellular_component											owl:Class	
GO:0102238	biolink:NamedThing	geraniol kinase activity (ATP-dependent) activity	Catalysis of the reaction: geraniol + ATP = geranyl monophosphate + ADP + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-12307									molecular_function											owl:Class	
GO:0047094	biolink:NamedThing	3-hydroxyphenylacetate 6-hydroxylase activity	Catalysis of the reaction: O2 + NAD(P)H + 3-hydroxyphenylacetate = H2O + NAD(P)+ + homogentisate.	tmpzr1t_l9r_go_relaxed.owl	3-hydroxyphenylacetate,NAD(P)H:oxygen oxidoreductase (6-hydroxylating)|3-hydroxyphenylacetate 6-monooxygenase activity				MetaCyc:1.14.13.63-RXN|EC:1.14.13.63									molecular_function											owl:Class	
GO:0070273	biolink:NamedThing	phosphatidylinositol-4-phosphate binding	Binding to phosphatidylinositol-4-phosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 4' position.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0097353	biolink:NamedThing	centrolateral pattern formation	The regionalization process in which the areas along the centrolateral axis are established that will lead to differences in cell differentiation, or in which cells interpret a specific environment.	tmpzr1t_l9r_go_relaxed.owl	mediolateral pattern formation							pr	2012-07-02T11:34:08Z					biological_process											owl:Class	
GO:1905275	biolink:NamedThing	Rohon-Beard neuron differentiation	The process in which a relatively unspecialized cell acquires the specialized features of a Rohon-Beard neuron.	tmpzr1t_l9r_go_relaxed.owl								cjm	2016-06-16T23:17:04Z					biological_process											owl:Class	
GO:0035044	biolink:NamedThing	sperm aster formation	Formation and organization of an aster composed of microtubule arrays originating from the sperm basal body and extending virtually to the egg periphery. The sperm aster ensures the appropriate positioning of the male and female pronuclei.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1902672	biolink:NamedThing	right anterior basal body	Any ciliary basal body that is part of a right anterior flagellum found in Giardia species (trophozoite stage).	tmpzr1t_l9r_go_relaxed.owl	cilial basal body of right anterior cilium|ciliary basal body of right anterior flagellum|cilium basal body of right anterior flagellum|microtubule basal body of right anterior flagellum|right anterior flagellum ciliary basal body|cilial basal body of right anterior flagellum|ciliary basal body of right anterior cilium|cilium basal body of right anterior cilium|microtubule basal body of right anterior cilium					Note that we deem cilium and microtubule-based flagellum to be equivalent. Also note that, due to the asymmetric nature of the Giardia trophozoite, this term is defined spatially as the trophozoite is viewed from the dorsal side, with the two nuclei dorsal to the ventral disc, and the ventral disc toward the anterior.		pr	2014-02-05T14:46:26Z					cellular_component											owl:Class	
GO:0047945	biolink:NamedThing	L-glutamine:pyruvate aminotransferase activity	Catalysis of the reaction: L-glutamine + pyruvate = 2-oxoglutaramate + L-alanine.	tmpzr1t_l9r_go_relaxed.owl	glutamine-keto acid aminotransferase activity|glutamine--pyruvate aminotransferase activity|glutamine-alpha-keto acid transaminase activity|glutamine-pyruvate transaminase activity|glutamine-oxo acid aminotransferase activity|L-glutamine transaminase L|gamma-glutaminyltransferase activity|glutamine--oxo-acid transaminase activity|glutaminase II activity|glutamine transaminase activity|glutamine-alpha-keto acid transamidase activity|glutamine transaminase L activity				KEGG_REACTION:R00576|RHEA:10400|MetaCyc:GLUTAMINE--PYRUVATE-AMINOTRANSFERASE-RXN|Reactome:R-HSA-893616|EC:2.6.1.15									molecular_function											owl:Class	
GO:0047185	biolink:NamedThing	N-acetylneuraminate 4-O-acetyltransferase activity	Catalysis of the reaction: N-acetylneuraminate + acetyl-CoA = N-acetyl-4-O-acetylneuraminate + CoA.	tmpzr1t_l9r_go_relaxed.owl	sialate O-acetyltransferase|acetyl-CoA:N-acetylneuraminate 4-O-acetyltransferase activity				EC:2.3.1.44|KEGG_REACTION:R01806|RHEA:18305|MetaCyc:2.3.1.44-RXN									molecular_function											owl:Class	
GO:1902790	biolink:NamedThing	undecan-2-one metabolic process	The chemical reactions and pathways involving undecan-2-one.	tmpzr1t_l9r_go_relaxed.owl	undecan-2-one metabolism							tt	2014-03-22T02:13:01Z					biological_process											owl:Class	
GO:0046254	biolink:NamedThing	anaerobic toluene catabolic process	The chemical reactions and pathways resulting in the breakdown of toluene, a volatile monoaromatic hydrocarbon found in crude petroleum and petroleum products, in the absence of oxygen.	tmpzr1t_l9r_go_relaxed.owl	anaerobic toluene catabolism|anaerobic toluene degradation|anaerobic toluene breakdown				MetaCyc:PWY-81									biological_process											owl:Class	
GO:0098684	biolink:NamedThing	photoreceptor ribbon synapse	A ribbon synapse between a retinal photoreceptor cell (rod or cone) and a retinal bipolar cell.  These contain a plate-like synaptic ribbon.	tmpzr1t_l9r_go_relaxed.owl								dos	2017-02-05T16:26:27Z					cellular_component											owl:Class	
GO:0018460	biolink:NamedThing	cyclohexanol dehydrogenase activity	Catalysis of the reaction: cyclohexanol + NAD+ = cyclohexanone + NADH + H+.	tmpzr1t_l9r_go_relaxed.owl	cyclohexanol:NAD+ oxidoreductase activity				EC:1.1.1.245|UM-BBD_reactionID:r0165|RHEA:10044|MetaCyc:CYCLOHEXANOL-DEHYDROGENASE-RXN									molecular_function											owl:Class	
GO:0004316	biolink:NamedThing	3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity	Catalysis of the reaction: (3R)-3-hydroxyacyl-[acyl-carrier protein] + NADP+ = 3-oxoacyl-[acyl-carrier protein] + NADPH + H+.	tmpzr1t_l9r_go_relaxed.owl	beta-ketoacyl-acyl-carrier protein(ACP) reductase activity|beta-ketoacyl thioester reductase activity|beta-ketoacyl acyl carrier protein (ACP) reductase activity|beta-ketoacyl-acyl carrier protein reductase activity|3-oxoacyl-acyl-carrier-protein reductase activity|3-oxoacyl-[acyl-carrier protein] reductase activity|3-ketoacyl acyl carrier protein reductase activity|NADPH-specific 3-oxoacyl-acylcarrier proteinreductase activity|3-oxoacyl-ACP reductase activity|beta-ketoacyl-ACP reductase activity|beta-ketoacyl reductase activity|3-oxoacyl-ACPreductase activity|(3R)-3-hydroxyacyl-acyl-carrier-protein:NADP+ oxidoreductase activity	https://github.com/geneontology/go-ontology/issues/21876			RHEA:17397|EC:1.1.1.100|Reactome:R-HSA-8862152|MetaCyc:3-OXOACYL-ACP-REDUCT-RXN									molecular_function											owl:Class	
GO:0046163	biolink:NamedThing	heme C catabolic process	The chemical reactions and pathways resulting in the breakdown of heme C, a derivative of heme found in cytochromes c, b4, and f.	tmpzr1t_l9r_go_relaxed.owl	haem C catabolism|heme C breakdown|heme C catabolism|heme C degradation|haem C catabolic process													biological_process											owl:Class	
GO:0002301	biolink:NamedThing	CD4-positive, alpha-beta intraepithelial T cell differentiation	The process in which a precursor cell type acquires the specialized features of a CD4-positive, alpha-beta intraepithelial T cell. Intraepithelial T cells are found among epithelial cells in mucosal areas and have distinct phenotypes and developmental pathways.	tmpzr1t_l9r_go_relaxed.owl	CD4-positive, alpha-beta intraepithelial T-lymphocyte differentiation|CD4-positive, alpha-beta intraepithelial T cell development|CD4-positive, alpha-beta intraepithelial T lymphocyte differentiation|CD4-positive, alpha-beta intraepithelial T-cell differentiation					Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.								biological_process											owl:Class	
GO:0047491	biolink:NamedThing	poly(alpha-L-guluronate) lyase activity	Catalysis of the reaction: polysaccharides containing a terminal alpha-L-guluronate group = oligosaccharides with 4-deoxy-alpha-L-erythro-hex-4-enuronosyl end. This reaction is the eliminative cleavage of polysaccharides containing a terminal a-L-guluronate group, to give oligopolysaccharides with 4-deoxy-a-L-erythro-hex-4-enuronosyl groups at their nonreducing ends.	tmpzr1t_l9r_go_relaxed.owl	poly-alpha-L-guluronate lyase activity|polyguluronate-specific alginate lyase activity|L-guluronan lyase activity|alginase II activity|guluronate lyase activity|poly(alpha-L-1,4-guluronide) exo-lyase activity|L-guluronate lyase activity				MetaCyc:4.2.2.11-RXN|EC:4.2.2.11									molecular_function											owl:Class	
GO:1904612	biolink:NamedThing	response to 2,3,7,8-tetrachlorodibenzodioxine	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 2,3,7,8-tetrachlorodibenzodioxine stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to dioxin|response to TCDD							sl	2015-08-27T19:01:52Z					biological_process											owl:Class	
GO:0002149	biolink:NamedThing	hypochlorous acid biosynthetic process	The chemical reactions and pathways resulting in the formation of hypochlorous acid.	tmpzr1t_l9r_go_relaxed.owl	HOCl biosynthetic process|HClO biosynthetic process|hypochlorite biosynthetic process|hypochlorous acid biosynthesis					Note that this reaction is catalyzed by myeloperoxidase in neutrophils.		hjd	2009-10-13T10:32:35Z					biological_process											owl:Class	
GO:0006564	biolink:NamedThing	L-serine biosynthetic process	The chemical reactions and pathways resulting in the formation of L-serine, the L-enantiomer of serine, i.e. (2S)-2-amino-3-hydroxypropanoic acid.	tmpzr1t_l9r_go_relaxed.owl	L-serine formation|L-serine biosynthesis|L-serine anabolism|L-serine synthesis				MetaCyc:SERSYN-PWY									biological_process											owl:Class	
GO:1904097	biolink:NamedThing	acid phosphatase complex	A protein complex which is capable of acid phosphatase activity.	tmpzr1t_l9r_go_relaxed.owl						An example of this is ACPP in human (UniProt symbol P15309) in PMID:22389722 (inferred from physical interaction).		bhm	2015-03-27T14:36:36Z					cellular_component											owl:Class	
GO:0050296	biolink:NamedThing	stipitatonate decarboxylase activity	Catalysis of the reaction: H(2)O + stipitatonate = CO(2) + H(+) + stipitatate.	tmpzr1t_l9r_go_relaxed.owl	stipitatonate carboxy-lyase (decyclizing, stipitatate-forming)|stipitatonate carboxy-lyase (decyclizing)				KEGG_REACTION:R03739|MetaCyc:STIPITATONATE-DECARBOXYLASE-RXN|EC:4.1.1.60|RHEA:13885									molecular_function											owl:Class	
GO:0009234	biolink:NamedThing	menaquinone biosynthetic process	The chemical reactions and pathways resulting in the formation of any of the menaquinones. Structurally, menaquinones consist of a methylated naphthoquinone ring structure and side chains composed of a variable number of unsaturated isoprenoid residues. Menaquinones that have vitamin K activity and are known as vitamin K2.	tmpzr1t_l9r_go_relaxed.owl	vitamin K2 biosynthesis|menaquinone anabolism|vitamin K2 biosynthetic process|multiprenylmenaquinone biosynthesis|menatetrenone biosynthetic process|menaquinone formation|menatetrenone biosynthesis|menaquinone biosynthesis|menaquinone synthesis|multiprenylmenaquinone biosynthetic process				MetaCyc:MENAQUINONESYN-PWY									biological_process											owl:Class	
GO:0090582	biolink:NamedThing	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity	Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein S-phosphocysteine + D-fructose(out) = protein cysteine + D-fructose-1-phosphate(in).	tmpzr1t_l9r_go_relaxed.owl								tb	2014-06-04T16:22:31Z					molecular_function											owl:Class	
GO:0047540	biolink:NamedThing	2-enoate reductase activity	Catalysis of the reaction: butanoate + NAD+ = 2-butenoate + NADH + H+.	tmpzr1t_l9r_go_relaxed.owl	enoate reductase activity|butanoate:NAD+ delta2-oxidoreductase activity				EC:1.3.1.31|MetaCyc:2-ENOATE-REDUCTASE-RXN|RHEA:10200									molecular_function											owl:Class	
GO:0012507	biolink:NamedThing	ER to Golgi transport vesicle membrane	The lipid bilayer surrounding a vesicle transporting substances from the endoplasmic reticulum to the Golgi.	tmpzr1t_l9r_go_relaxed.owl	endoplasmic reticulum-Golgi transport vesicle membrane|ER to Golgi constitutive secretory pathway transport vesicle membrane|endoplasmic reticulum to Golgi transport vesicle membrane|COPII coated vesicle membrane|ER-Golgi transport vesicle membrane											GO:0030664		cellular_component											owl:Class	
GO:0031964	biolink:NamedThing	beta-alanyl-histamine hydrolase activity	Catalysis of the reaction: N-beta-alanyl histamine + H2O = histamine + beta-alanine.	tmpzr1t_l9r_go_relaxed.owl	carcinine hydrolase activity													molecular_function											owl:Class	
GO:0004768	biolink:NamedThing	stearoyl-CoA 9-desaturase activity	Catalysis of the reaction: stearoyl-CoA + 2 ferrocytochrome b5 + O2 + 2 H+ = oleoyl-CoA + 2 ferricytochrome b5 + 2 H2O.	tmpzr1t_l9r_go_relaxed.owl	delta9-desaturase|delta(9)-desaturase activity|fatty acid desaturase|stearoyl-CoA desaturase activity|acyl-CoA desaturase				EC:1.14.19.1|MetaCyc:1.14.19.1-RXN|RHEA:19721|Reactome:R-HSA-5690565|Reactome:R-HSA-8847579	Note that this function was formerly EC:1.14.99.5.						GO:0016214|GO:0043735		molecular_function											owl:Class	
GO:1904768	biolink:NamedThing	all-trans-retinol binding	Binding to all-trans-retinol.	tmpzr1t_l9r_go_relaxed.owl								kmv	2015-10-27T21:14:47Z					molecular_function											owl:Class	
GO:0030769	biolink:NamedThing	macrocin O-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine(1+) + macrocin = S-adenosyl-L-homocysteine + H(+) + tylosin.	tmpzr1t_l9r_go_relaxed.owl	S-adenosyl-L-methionine:macrocin 3'''-O-methyltransferase activity|macrocin methyltransferase activity|S-adenosyl-L-methionine-macrocin O-methyltransferase activity				KEGG_REACTION:R02858|EC:2.1.1.101|MetaCyc:MACROCIN-O-METHYLTRANSFERASE-RXN|RHEA:17269									molecular_function											owl:Class	
GO:0106239	biolink:NamedThing	9,13-epoxylabda-14-ene synthase activity	Catalysis of the reaction:peregrinol diphosphate = (13R)-9,13-epoxylabd-14-ene + diphosphate.	tmpzr1t_l9r_go_relaxed.owl					RHEA:54512|EC:4.2.3.189			hjd	2019-12-19T16:00:49Z					molecular_function											owl:Class	
GO:0050080	biolink:NamedThing	malonyl-CoA decarboxylase activity	Catalysis of the reaction: malonyl-CoA = acetyl-CoA + CO2.	tmpzr1t_l9r_go_relaxed.owl	malonyl-CoA carboxy-lyase activity|malonyl-CoA carboxy-lyase (acetyl-CoA-forming)|malonyl coenzyme A decarboxylase activity				RHEA:18781|MetaCyc:MALONYL-COA-DECARBOXYLASE-RXN|Reactome:R-HSA-977317|EC:4.1.1.9									molecular_function											owl:Class	
GO:0018703	biolink:NamedThing	2,4-dichlorophenoxyacetate dehalogenase activity	Catalysis of the reaction: 2,4-dichlorophenoxyacetic acid + H+ + 2 e- = Cl- + 4-chlorophenoxyacetate.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0280									molecular_function											owl:Class	
GO:0044299	biolink:NamedThing	C-fiber	The axon of a dorsal root ganglion cell that are responsive to pain and temperature. C-fibers are small in diameter (0.2-1.5 um) and unmyelinated.	tmpzr1t_l9r_go_relaxed.owl	C-fibre				NIF_Subcellular:nlx_subcell_20090210			jl	2010-02-05T11:14:51Z					cellular_component											owl:Class	
GO:0018581	biolink:NamedThing	hydroxyquinol 1,2-dioxygenase activity	Catalysis of the reaction: benzene-1,2,4-triol + O2 = 3-hydroxy-cis,cis-muconate.	tmpzr1t_l9r_go_relaxed.owl	hydroxyquinol dioxygenase activity|benzene-1,2,4-triol:oxygen 1,2-oxidoreductase (decyclizing)				UM-BBD_reactionID:r0232|EC:1.13.11.37|RHEA:19441|MetaCyc:HYDROXYQUINOL-12-DIOXYGENASE-RXN									molecular_function											owl:Class	
GO:0050006	biolink:NamedThing	isomaltulose synthase activity	Catalysis of the reaction: sucrose = 6-O-alpha-D-glucopyranosyl-D-fructofuranose.	tmpzr1t_l9r_go_relaxed.owl	trehalulose synthase activity|sucrose glucosylmutase activity|isomaltulose synthetase activity|sucrose alpha-glucosyltransferase activity				RHEA:24032|EC:5.4.99.11|MetaCyc:ISOMALTULOSE-SYNTHASE-RXN									molecular_function											owl:Class	
GO:0061527	biolink:NamedThing	dopamine secretion, neurotransmission	The regulated release of dopamine by a cell in which the dopamine acts as a neurotransmitter.	tmpzr1t_l9r_go_relaxed.owl								dph	2013-06-21T15:43:15Z					biological_process											owl:Class	
GO:0022831	biolink:NamedThing	narrow pore, gated channel activity	Enables the transport of a solute across a membrane via a narrow pore channel that opens in response to a particular stimulus.	tmpzr1t_l9r_go_relaxed.owl	ion channels				Wikipedia:Ion_channels									molecular_function											owl:Class	
GO:0106273	biolink:NamedThing	cytosol to ERGIC protein transport	The directed movement of proteins from the cystosol to the endoplasmic reticulum-Golgi intermediate compartment (ERGIC).	tmpzr1t_l9r_go_relaxed.owl								hjd	2020-07-01T17:28:07Z					biological_process											owl:Class	
GO:0000111	biolink:NamedThing	nucleotide-excision repair factor 2 complex	One of several protein complexes involved in nucleotide-excision repair; possesses damaged DNA binding activity. In S. cerevisiae, it is composed of Rad4p and Rad23p.	tmpzr1t_l9r_go_relaxed.owl	NEF2 complex					Note that process and function information are included in the term and definition for the purpose of describing and distinguishing the complex.								cellular_component											owl:Class	
GO:0008456	biolink:NamedThing	alpha-N-acetylgalactosaminidase activity	Catalysis of the hydrolysis of terminal non-reducing N-acetyl-D-galactosamine residues in N-acetyl-alpha-D-galactosaminides.	tmpzr1t_l9r_go_relaxed.owl	alpha-NAGA activity|alpha-N-acetyl-D-galactosaminide N-acetylgalactosaminohydrolase activity|N-acetyl-alpha-galactosaminidase activity|alpha-acetylgalactosaminidase activity|N-acetyl-alpha-D-galactosaminidase activity|alpha-galactosidase B activity				EC:3.2.1.49|MetaCyc:3.2.1.49-RXN|RHEA:15085									molecular_function											owl:Class	
GO:0102627	biolink:NamedThing	parthenolide 3beta-hydroxylase activity	Catalysis of the reaction: parthenolide + NADPH + O2 + H+ <=> 3beta-hydroxyparthenolide + NADP + H2O.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-15532									molecular_function											owl:Class	
GO:0070412	biolink:NamedThing	R-SMAD binding	Binding to a receptor-regulated SMAD signaling protein.	tmpzr1t_l9r_go_relaxed.owl	pathway-restricted SMAD binding|receptor-regulated SMAD binding|pathway restricted SMAD binding|receptor regulated SMAD binding													molecular_function											owl:Class	
GO:0071315	biolink:NamedThing	cellular response to morphine	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a morphine stimulus. Morphine is an opioid alkaloid, isolated from opium, with a complex ring structure.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-12-10T04:53:46Z					biological_process											owl:Class	
GO:0044101	biolink:NamedThing	(R)-citramalyl-CoA lyase activity	Catalysis of the reaction: (R)-citramalyl-CoA = pyruvate + acetyl-CoA.	tmpzr1t_l9r_go_relaxed.owl	R-citramalyl-CoA lyase activity|Ccl				EC:4.1.3.46|MetaCyc:RXN-8967			jl	2009-07-09T03:14:15Z					molecular_function											owl:Class	
GO:0048537	biolink:NamedThing	mucosa-associated lymphoid tissue development	The process whose specific outcome is the progression of mucosal-associated lymphoid tissue over time, from its formation to the mature structure. Mucosal-associated lymphoid tissue is typically found as nodules associated with mucosal epithelia with distinct internal structures including B- and T-zones for the activation of lymphocytes.	tmpzr1t_l9r_go_relaxed.owl	GALT development|NALT development|BALT development|nasopharyngeal-associated lymphoid tissue development|gut-associated lymphoid tissue development|mucosal-associated lymphoid tissue development|bronchial-associated lymphoid tissue development	https://github.com/geneontology/go-ontology/issues/19918												biological_process											owl:Class	
GO:0071874	biolink:NamedThing	cellular response to norepinephrine stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a norepinephrine stimulus. Norepinephrine is a catecholamine that has the formula C8H11NO3; it acts as a hormone, and as a neurotransmitter in most of the sympathetic nervous system.	tmpzr1t_l9r_go_relaxed.owl	cellular response to noradrenaline stimulus					Note that epinephrine and norepinephrine are ligands for the same receptors, and there are multiple adrenergic receptors.		mah	2010-09-13T03:33:32Z					biological_process											owl:Class	
GO:0008935	biolink:NamedThing	1,4-dihydroxy-2-naphthoyl-CoA synthase activity	Catalysis of the reaction: 2-succinylbenzoyl-CoA + H+ = 1,4-dihydroxy-2-naphthoyl-CoA + H2O.	tmpzr1t_l9r_go_relaxed.owl	dihydroxynaphthoic acid synthetase activity|O-succinylbenzoyl-CoA 1,4-dihydroxy-2-naphthoate-lyase (cyclizing) activity|dihydroxynaphthoate synthase activity|DHNA synthetase activity|naphthoate synthase activity	https://github.com/geneontology/go-ontology/issues/21763			RHEA:26562|KEGG_REACTION:R04150|EC:4.1.3.36|MetaCyc:NAPHTHOATE-SYN-RXN									molecular_function											owl:Class	
GO:0036038	biolink:NamedThing	MKS complex	A protein complex that is located at the ciliary transition zone and consists of several proteins some of which are membrane bound. Acts as an organiser of transition zone inner structure, specifically the Y-shaped links, in conjunction with the NPHP complex. The MKS complex also acts as part of the selective barrier that prevents diffusion of proteins between the ciliary cytoplasm and cellular cytoplasm as well as between the ciliary membrane and plasma membrane.	tmpzr1t_l9r_go_relaxed.owl	tectonic complex|tectonic-like complex|MKS module|TCTN-B9D complex|B9 complex					Although there is some evidence, it is still unclear if the MKS and NPHP complexes are constituents parts of the Y-shaped links or are simply responsible for aligning and attaching the Y-shaped links to the membrane and axoneme.		bf	2011-11-22T11:21:28Z					cellular_component											owl:Class	
GO:0033891	biolink:NamedThing	CC-preferring endodeoxyribonuclease activity	Catalysis of the endonucleolytic cleavage to give 5'-phosphooligonucleotide end-products, with a preference for cleavage within the sequence CC.	tmpzr1t_l9r_go_relaxed.owl	Streptomyces glaucescens exocytoplasmic dodeoxyribonuclease activity|Streptomyces glaucescens exocytoplasmic endonuclease activity|Streptomyces glaucescens exocytoplasmic endodeoxyribonuclease activity|5'-CC-3'-preferring endodeoxyribonuclease activity				EC:3.1.21.6|MetaCyc:3.1.21.6-RXN									molecular_function											owl:Class	
GO:0102832	biolink:NamedThing	verbascose galactinol:ajugose galactosyltransferase activity	Catalysis of the reaction: verbascose + alpha-D-galactosyl-(1->3)-1D-myo-inositol <=> ajugose + myo-inositol.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-8288									molecular_function											owl:Class	
GO:1902860	biolink:NamedThing	propionyl-CoA biosynthetic process	The chemical reactions and pathways resulting in the formation of propionyl-CoA.	tmpzr1t_l9r_go_relaxed.owl	propionyl-CoA formation|propionyl-CoA anabolism|propionyl-CoA synthesis|propionyl-CoA biosynthesis							tt	2014-04-03T03:10:29Z					biological_process											owl:Class	
GO:0051719	biolink:NamedThing	DNA (cytosine-5-)-methyltransferase activity, acting on CpN substrates	Catalysis of the reaction: S-adenosyl-L-methionine + DNA containing CpN = S-adenosyl-L-homocysteine + DNA containing 5-MeCpN.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-5334097|Reactome:R-HSA-5334152									molecular_function											owl:Class	
GO:0031173	biolink:NamedThing	otolith mineralization completed early in development	The formation of otoliths during embryogenesis with completion in early postembryonic development. Formation occurs by precipitation of specific crystal forms of calcium carbonate around an organic core of extracellular matrix proteins. Otoconia (otoliths) are small (~10 micron) dense extracellular particles present in the otolith end organs of the vertebrate inner ear.	tmpzr1t_l9r_go_relaxed.owl	otoconium mineralization|otoconia mineralization													biological_process											owl:Class	
GO:0048036	biolink:NamedThing	central complex development	The process whose specific outcome is the progression of the central complex over time, from its formation to the mature structure. The central complex region of the insect brain is thought to be crucial for control of locomotive behavior. Located in the middle of the two protocerebral hemispheres, it comprises four neuropilar regions, the fan-shaped body, the ellipsoid body, the protocerebral bridge and the paired noduli.	tmpzr1t_l9r_go_relaxed.owl	central body development													biological_process											owl:Class	
GO:0033391	biolink:NamedThing	chromatoid body	A ribonucleoprotein complex found in the cytoplasm of male germ cells, composed of exceedingly thin filaments that are consolidated into a compact mass or into dense strands of varying thickness that branch to form an irregular network. Contains mRNAs, miRNAs, and protein components involved in miRNA processing (such as Argonaute proteins and the endonuclease Dicer) and in RNA decay (such as the decapping enzyme DCP1a and GW182).	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0102604	biolink:NamedThing	naringenin,NADPH:oxygen oxidoreductase activity	Catalysis of the reaction: (S)-naringenin(1-) + O2 + NADPH + H+ <=> 2-hydroxy-2,3-dihydrogenistein-7-olate + NADP + H2O.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-1541|RHEA:35487|EC:1.14.14.87									molecular_function											owl:Class	
GO:0021608	biolink:NamedThing	accessory nerve formation	The process that gives rise to the accessory nerve. This process pertains to the initial formation of a structure from unspecified parts. The spinal branch of this motor nerve innervates the trapezius and the sternocleidomastoid muscles. The cranial branch joins the vagus nerve and innervates the same targets as the vagus nerve.	tmpzr1t_l9r_go_relaxed.owl	CN XI biosynthesis|CN XI formation													biological_process											owl:Class	
GO:0015680	biolink:NamedThing	protein maturation by copper ion transfer	A process that contributes to the delivery of copper ions to a target protein.	tmpzr1t_l9r_go_relaxed.owl	intracellular copper ion delivery|intracellular copper ion transport|intracellular copper delivery													biological_process											owl:Class	
GO:0103083	biolink:NamedThing	methylthiobutylmalate isomerase activity	Catalysis of the reaction: 2-(4'-methylthio)butylmalate <=> 3-(4'-methylthio)butylmalate.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXNQT-4167									molecular_function											owl:Class	
GO:0140552	biolink:NamedThing	TEAD-YAP complex	A transcription factor complex that is composed of the one DNA binding protein of the TEAD family and the transcriptional coactivator YAP.	tmpzr1t_l9r_go_relaxed.owl	TEAD-4-YAP complex|TEAD-2 multiprotein complex|TEAD-1-YAP complex|TEAD-2-YAP complex|TEAD-3-YAP complex	https://github.com/geneontology/go-ontology/issues/9300			CORUM:2870			pg	2020-11-17T07:05:23Z			GO:0071150|GO:0071148|GO:0071149|GO:0071151|GO:0071147		cellular_component											owl:Class	
GO:0002160	biolink:NamedThing	desmosome maintenance	The maintenance of a desmosome. A desmosome is a patch-like intercellular junctions found in vertebrate tissues, consisting of parallel zones of two cell membranes, separated by an interspace of 25-35 nm, and having dense fibrillar plaques in the subjacent cytoplasm.	tmpzr1t_l9r_go_relaxed.owl						Desmosomes link two cells together; hemidesmosomes attach one cell to the extracellular matrix.		hjd	2010-02-09T10:50:59Z					biological_process											owl:Class	
GO:0032944	biolink:NamedThing	regulation of mononuclear cell proliferation	Any process that modulates the frequency, rate or extent of mononuclear cell proliferation.	tmpzr1t_l9r_go_relaxed.owl	regulation of peripheral blood mononuclear cell proliferation|regulation of PBMC proliferation													biological_process											owl:Class	
GO:0050096	biolink:NamedThing	methylaspartate ammonia-lyase activity	Catalysis of the reaction: threo-3-methyl-L-aspartate = mesaconate + NH(4)(+).	tmpzr1t_l9r_go_relaxed.owl	L-threo-3-methylaspartate ammonia-lyase (mesaconate-forming)|L-threo-3-methylaspartate ammonia-lyase activity|beta-methylaspartase activity|3-methylaspartase activity				KEGG_REACTION:R03696|EC:4.3.1.2|RHEA:12829|MetaCyc:METHYLASPARTATE-AMMONIA-LYASE-RXN									molecular_function											owl:Class	
GO:0019458	biolink:NamedThing	methionine catabolic process via 2-oxobutanoate	The chemical reactions and pathways resulting in the breakdown of methionine, via the intermediate 2-oxobutanoate.	tmpzr1t_l9r_go_relaxed.owl	methionine breakdown via 2-oxobutanoate|methionine degradation via 2-oxobutanoate				MetaCyc:PWY-701									biological_process											owl:Class	
GO:0017067	biolink:NamedThing	tyrosine-ester sulfotransferase activity	Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + L-tyrosine methyl ester = L-tyrosine methyl ester 4-sulfate + adenosine 3',5'-diphosphate + H(+).	tmpzr1t_l9r_go_relaxed.owl	aryl sulfotransferase IV|3'-phosphoadenylyl-sulfate:L-tyrosine-methyl-ester sulfotransferase activity|tyrosine-ester sulphotransferase activity|L-tyrosine methyl ester sulfotransferase activity				KEGG_REACTION:R04213|EC:2.8.2.9|MetaCyc:TYROSINE-ESTER-SULFOTRANSFERASE-RXN|RHEA:19977							GO:0008128		molecular_function											owl:Class	
GO:0050272	biolink:NamedThing	S-carboxymethylcysteine synthase activity	Catalysis of the reaction: 3-chloro-L-alanine + thioglycolate = S-carboxymethyl-L-cysteine + chloride + H(+).	tmpzr1t_l9r_go_relaxed.owl	3-chloro-L-alanine chloride-lyase (adding thioglycolate)|3-chloro-L-alanine chloride-lyase (adding thioglycolate; S-carboxymethyl-L-cysteine-forming)|S-carboxymethyl-L-cysteine synthase activity				RHEA:22868|KEGG_REACTION:R04003|MetaCyc:S-CARBOXYMETHYLCYSTEINE-SYNTHASE-RXN|EC:4.5.1.5									molecular_function											owl:Class	
GO:0042410	biolink:NamedThing	6-carboxyhexanoate-CoA ligase activity	Catalysis of the reaction: ATP + CoA + pimelate = AMP + diphosphate + H(+) + pimelyl-CoA.	tmpzr1t_l9r_go_relaxed.owl	6-carboxyhexanoate:CoA ligase (AMP-forming)|pimeloyl-CoA synthetase activity|6-carboxyhexanoyl-CoA synthetase activity|pimelyl-CoA synthetase activity				RHEA:14781|KEGG_REACTION:R03209|MetaCyc:6-CARBOXYHEXANOATE--COA-LIGASE-RXN|EC:6.2.1.14									molecular_function											owl:Class	
GO:0009342	biolink:NamedThing	glutamate synthase complex (NADPH)	A complex that possesses glutamate synthase (NADPH) activity.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0097487	biolink:NamedThing	multivesicular body, internal vesicle	A membrane-bounded vesicle wholly contained within a multivesicular body.	tmpzr1t_l9r_go_relaxed.owl								pr	2013-07-08T20:34:51Z					cellular_component											owl:Class	
GO:0090213	biolink:NamedThing	regulation of radial pattern formation	Any process that modulates the rate, frequency or extent of radial pattern formation, the regionalization process that results in defined areas around a point in which specific types of cell differentiation will occur.	tmpzr1t_l9r_go_relaxed.owl	regulation of radial pattern specification							tb	2010-01-05T10:59:10Z					biological_process											owl:Class	
GO:0003233	biolink:NamedThing	bulbus arteriosus morphogenesis	The process in which the bulbus arteriosus is generated and organized. The bulbus arteriosus is an elastic cardiac chamber.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-10-13T11:07:30Z					biological_process											owl:Class	
GO:0047840	biolink:NamedThing	dCTP diphosphatase activity	Catalysis of the reaction: dCTP + H2O = dCMP + diphosphate.	tmpzr1t_l9r_go_relaxed.owl	dCTPase activity|dCTP pyrophosphatase activity|dCTP nucleotidohydrolase activity|deoxy-CTPase activity|deoxycytidine-triphosphatase activity|deoxycytidine triphosphatase activity				EC:3.6.1.12|RHEA:22636|Reactome:R-HSA-6786257|MetaCyc:DCTP-PYROPHOSPHATASE-RXN									molecular_function											owl:Class	
GO:0047597	biolink:NamedThing	6-oxocineole dehydrogenase activity	Catalysis of the reaction: 6-oxocineole + H(+) + NADPH + O(2) = 1,6,6-trimethyl-2,7-dioxabicyclo[3.2.2]nonan-3-one + H(2)O + NADP(+).	tmpzr1t_l9r_go_relaxed.owl	6-oxocineole oxygenase activity|6-oxocineole,NADPH:oxygen oxidoreductase activity				KEGG_REACTION:R02995|EC:1.14.13.51|RHEA:24324|MetaCyc:6-OXOCINEOLE-DEHYDROGENASE-RXN									molecular_function											owl:Class	
GO:0140295	biolink:NamedThing	pathogen-derived receptor ligand activity	The activity of a pathogen-derived entity that interacts with a host receptor to activate effector-triggered immunity.	tmpzr1t_l9r_go_relaxed.owl	innate receptor ligand activity	https://github.com/geneontology/go-ontology/issues/16656|https://github.com/geneontology/go-ontology/issues/19194				Note that this term is meant to annotate effectors for which the evolved activity is to act as a ligand to activate (for necrotrophs) or suppress (for biotrophs) the host immune system. It should not be used to annotate PAMPs (pathogen-associated molecular pattern molecules) or similar types of microbial proteins recognized by the host innate immune system (for example, PAMPs are recognized by toll-like receptors (TLRs) and other pattern recognition receptors (PRRs) in both plants and animals). PAMPs activate innate immune responses, protecting the host from infection, but this is not the molecular function of PAMPs; those usually form the structure of the bacterial cell wall.		pg	2018-11-26T13:30:21Z					molecular_function											owl:Class	
GO:0006307	biolink:NamedThing	DNA dealkylation involved in DNA repair	The repair of alkylation damage, e.g. the removal of the alkyl group at the O6-position of guanine by O6-alkylguanine-DNA alkyltransferase (AGT).	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0043818	biolink:NamedThing	precorrin-3B synthase activity	Catalysis of the reaction: H(+) + NADH + O(2) + precorrin-3A = H(2)O + NAD(+) + precorrin-3B.	tmpzr1t_l9r_go_relaxed.owl	precorrin-3A,NADH:oxygen oxidoreductase (20-hydroxylating)|precorrin-3X synthase activity|CobG				RHEA:17293|MetaCyc:R321-RXN|EC:1.14.13.83|KEGG_REACTION:R05217									molecular_function											owl:Class	
GO:0039009	biolink:NamedThing	rectal diverticulum development	The process whose specific outcome is the progression of the rectal diverticulum over time, from its formation to the mature structure. The rectal diverticulum is an outgrowth of the cloaca and links the pronephric kidney to the exterior.	tmpzr1t_l9r_go_relaxed.owl	pronephric rectal diverticulum development							bf	2010-07-02T09:48:58Z					biological_process											owl:Class	
GO:0015167	biolink:NamedThing	arabitol transmembrane transporter activity	Enables the transfer of an arabitol from one side of a membrane to the other. Arabitol is the pentitol derived from arabinose or lyxose by reduction of the aldehyde group. The D enantiomer is present in lichens and mushrooms.	tmpzr1t_l9r_go_relaxed.owl	arabinitol transporter activity													molecular_function											owl:Class	
GO:0033957	biolink:NamedThing	lambda-carrageenase activity	Catalysis of the endohydrolysis of beta-1,4-linkages in the backbone of lambda-carrageenan, resulting in the tetrasaccharide alpha-D-Galp2,6S2-(1->3)-beta-D-Galp2S-(1->4)-alpha-D-Galp2,6S2-(1->3)-D-Galp2S.	tmpzr1t_l9r_go_relaxed.owl	endo-beta-1,4-carrageenose 2,6,2'-trisulfate-hydrolase activity				MetaCyc:3.2.1.162-RXN|EC:3.2.1.162									molecular_function											owl:Class	
GO:0003049	biolink:NamedThing	regulation of systemic arterial blood pressure by capillary fluid shift	The intrinsic circulatory process resulting from capillary fluid shift that modulates the force with which blood travels through the systemic arterial circulatory system. Capillary fluid shift is the movement of fluid across the capillary membrane between the blood and the interstitial fluid compartment.	tmpzr1t_l9r_go_relaxed.owl	blood pressure regulation by capillary fluid shift													biological_process											owl:Class	
GO:0072551	biolink:NamedThing	diferuloyl mono-(hydroxyferuloyl) spermidine meta-hydroxylase activity	Catalysis of the reaction: diferuloyl mono-(hydroxyferuloyl) spermidine + NADPH + O2 = monoferuloyl di-(hydroxyferuloyl) spermidine + NADP+ + H2O.	tmpzr1t_l9r_go_relaxed.owl								mah	2011-01-25T03:04:16Z					molecular_function											owl:Class	
GO:0004773	biolink:NamedThing	steryl-sulfatase activity	Catalysis of the reaction: 3-beta-hydroxyandrost-5-en-17-one 3-sulfate + H2O = 3-beta-hydroxyandrost-5-en-17-one + sulfate.	tmpzr1t_l9r_go_relaxed.owl	dehydroepiandrosterone sulfate sulfatase activity|steroid sulfate sulfohydrolase activity|steryl-sulfate sulfohydrolase activity|arylsulfatase C activity|steroid sulfatase activity|dehydroepiandrosterone sulfatase activity|phenolic steroid sulfatase activity|sterol sulfatase activity|steroid 3-sulfatase activity|3-beta-hydroxysteroid sulfate sulfatase activity|steryl-sulphatase activity|pregnenolone sulfatase activity				RHEA:19873|MetaCyc:STERYL-SULFATASE-RXN|EC:3.1.6.2|Reactome:R-HSA-1606839									molecular_function											owl:Class	
GO:0047452	biolink:NamedThing	protoaphin-aglucone dehydratase (cyclizing) activity	Catalysis of the reaction: protoaphin aglucone = H(2)O + xanthoaphin.	tmpzr1t_l9r_go_relaxed.owl	protoaphin dehydratase activity|protoaphin-aglucone hydro-lyase (cyclizing; xanthoaphin-forming)|protoaphin-aglucone hydro-lyase (cyclizing)|protoaphin dehydratase (cyclizing)				MetaCyc:4.2.1.73-RXN|EC:4.2.1.73|RHEA:23876|KEGG_REACTION:R03742									molecular_function											owl:Class	
GO:0040039	biolink:NamedThing	inductive cell migration	Migration of a cell in a multicellular organism that, having changed its location, is required to induce normal properties in one or more cells at its new location. An example of this would be the distal tip cells of Caenorhabditis elegans.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0070635	biolink:NamedThing	nicotinamide riboside hydrolase activity	Catalysis of the reaction: nicotinamide riboside + H2O = nicotinamide + D-ribose.	tmpzr1t_l9r_go_relaxed.owl	N-ribosylnicotinamide hydrolase activity|nicotinamide ribonucleoside hydrolase activity				MetaCyc:RXN-8441			mah	2009-05-07T02:01:42Z					molecular_function											owl:Class	
GO:0071122	biolink:NamedThing	alpha9-beta1 integrin-VEGF-A complex	A protein complex that consists of an alpha9-beta1 integrin complex bound to vascular endothelial growth factor A.	tmpzr1t_l9r_go_relaxed.owl	ITGA9-ITGB1-VEGFA complex							mah	2009-11-13T02:22:01Z					cellular_component											owl:Class	
GO:0019658	biolink:NamedThing	glucose fermentation to lactate and acetate	The anaerobic chemical reactions and pathways resulting in the breakdown of glucose to lactate and acetate, yielding energy in the form of ATP.	tmpzr1t_l9r_go_relaxed.owl	glucose catabolic process to lactate and acetate|bifidum pathway				MetaCyc:P124-PWY									biological_process											owl:Class	
GO:0060640	biolink:NamedThing	positive regulation of dentin-containing tooth bud formation by mesenchymal-epithelial signaling	Any process that initiates the formation of a tooth bud by the secretion of a signal from a mesenchymal cell and its reception and subsequent change in the identity of an epithelial cell of the tooth bud.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of dentine-containing tooth bud formation by mesenchymal-epithelial signaling|positive regulation of dentine-containing tooth bud formation by mesenchymal-epithelial signalling							dph	2009-05-20T04:33:52Z					biological_process											owl:Class	
GO:0043252	biolink:NamedThing	sodium-independent organic anion transport	The directed, sodium-independent, movement of organic anions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0033350	biolink:NamedThing	apiose biosynthetic process	The chemical reactions and pathways resulting in the formation of apiose, the branched tetrose 3-C-(hydroxymethyl)-D-glycero-tetrose.	tmpzr1t_l9r_go_relaxed.owl	apiose anabolism|apiose synthesis|apiose formation|apiose biosynthesis													biological_process											owl:Class	
GO:0033349	biolink:NamedThing	apiose metabolic process	The chemical reactions and pathways involving apiose, the branched tetrose 3-C-(hydroxymethyl)-D-glycero-tetrose.	tmpzr1t_l9r_go_relaxed.owl	apiose metabolism													biological_process											owl:Class	
GO:1990389	biolink:NamedThing	CUE1-UBC7 ubiquitin-conjugating enzyme complex	A protein complex capable of ubiquitin-conjugating enzyme activity during ER-associated protein degradation (ERAD). In S. cerevisiae, UBC7 is the ubiquitin-conjugating enzyme (E2) and requires binding to the ER surface by CUE1.	tmpzr1t_l9r_go_relaxed.owl	CUE1-UBC7 ubiquitin-conjugating enzyme (E2)					An example of this is UBC7 in Saccharomyces cerevisiae (Q02159) in PMID:16179953 (inferred from direct assay).		bhm	2014-06-02T15:35:58Z					cellular_component											owl:Class	
GO:0031172	biolink:NamedThing	ornithine N5-monooxygenase activity	Catalysis of the reaction: L-ornithine + O2 + H+ = N5-hydroxy-L-ornithine + H2O.	tmpzr1t_l9r_go_relaxed.owl	L-ornithine 5-monooxygenase activity				MetaCyc:RXN-11128|RHEA:41508									molecular_function											owl:Class	
GO:1990527	biolink:NamedThing	Tec1p-Ste12p-Dig1p complex	A multiprotein complex that is involved in the transcriptional regulation of primarily filamentation genes, but also mating genes, in the yeast S. cerevisiae.	tmpzr1t_l9r_go_relaxed.owl								rb	2014-11-05T22:55:17Z					cellular_component											owl:Class	
GO:0062213	biolink:NamedThing	peroxynitrite isomerase activity	Catalysis of the reaction: peroxynitrite = nitrate.	tmpzr1t_l9r_go_relaxed.owl					RHEA:63116			dph	2020-02-22T13:57:50Z					molecular_function											owl:Class	
GO:0036285	biolink:NamedThing	SAGA complex assembly	The aggregation, arrangement and bonding together of a set of components to form a SAGA complex, a SAGA-type histone acetyltransferase complex that contains Spt8 (in budding yeast) or a homolog thereof.	tmpzr1t_l9r_go_relaxed.owl	SAGA complex formation							bf	2012-07-16T10:30:00Z					biological_process											owl:Class	
GO:0016499	biolink:NamedThing	orexin receptor activity	Combining with orexin to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0042007	biolink:NamedThing	interleukin-18 binding	Binding to interleukin-18.	tmpzr1t_l9r_go_relaxed.owl	IL-18 binding													molecular_function											owl:Class	
GO:0030643	biolink:NamedThing	cellular phosphate ion homeostasis	Any process involved in the maintenance of an internal steady state of phosphate ions at the level of a cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0055062	biolink:NamedThing	phosphate ion homeostasis	Any process involved in the maintenance of an internal steady state of phosphate ions within an organism or cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0004581	biolink:NamedThing	dolichyl-phosphate beta-glucosyltransferase activity	Catalysis of the reaction: UDP-glucose + dolichyl phosphate = UDP + dolichyl beta-D-glucosyl phosphate.	tmpzr1t_l9r_go_relaxed.owl	UDP-glucose dolichyl-phosphate glucosyltransferase activity|UDP-glucose:dolichyl-phosphate beta-D-glucosyltransferase activity|uridine diphosphoglucose-dolichol glucosyltransferase activity|polyprenyl phosphate:UDP-D-glucose glucosyltransferase activity|UDP-glucose:dolichyl monophosphate glucosyltransferase activity|UDP-glucose:dolicholphosphoryl glucosyltransferase activity|UDPglucose:dolichyl-phosphate beta-D-glucosyltransferase activity|UDP-glucose:dolichyl phosphate glucosyltransferase activity|UDP-glucose:dolichol phosphate glucosyltransferase activity				EC:2.4.1.117|RHEA:15401|Reactome:R-HSA-446214|MetaCyc:2.4.1.117-RXN									molecular_function											owl:Class	
GO:0002151	biolink:NamedThing	G-quadruplex RNA binding	Binding to a G-quadruplex RNA structure, in which groups of four guanines adopt a flat, cyclic hydrogen-bonding arrangement known as a guanine tetrad.	tmpzr1t_l9r_go_relaxed.owl	G quadruplex binding|G quartet binding|G quartet RNA binding|G-quartet binding					The structures of RNA and DNA G quartets differ regarding sugar conformation so that a protein binding to the RNA structure might not bind to the DNA structure.		hjd	2009-10-22T01:38:02Z					molecular_function											owl:Class	
GO:2001296	biolink:NamedThing	N(omega)-methyl-L-arginine metabolic process	The chemical reactions and pathways involving N(omega)-methyl-L-arginine.	tmpzr1t_l9r_go_relaxed.owl	N(omega)-methyl-L-arginine metabolism							pr	2012-02-14T03:38:16Z					biological_process											owl:Class	
GO:0006049	biolink:NamedThing	UDP-N-acetylglucosamine catabolic process	The chemical reactions and pathways resulting in the breakdown of UDP-N-acetylglucosamine, a substance composed of N-acetylglucosamine, a common structural unit of oligosaccharides, in glycosidic linkage with uridine diphosphate.	tmpzr1t_l9r_go_relaxed.owl	UDP-N-acetylglucosamine catabolism|UDP-N-acetylglucosamine degradation|UDP-N-acetylglucosamine breakdown													biological_process											owl:Class	
GO:0060418	biolink:NamedThing	yolk plasma	Discrete structures that partition the water-soluble portion of the yolk of oocytes and ova, which may or may not be membrane enclosed.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0018459	biolink:NamedThing	carveol dehydrogenase activity	Catalysis of the reaction: (1S,5R)-carveol + NADP(+) = (R)-carvone + H(+) + NADPH.	tmpzr1t_l9r_go_relaxed.owl	(-)-trans-carveol:NADP+ oxidoreductase activity|(-)-trans-carveol dehydrogenase activity				UM-BBD_reactionID:r0714|RHEA:13629|KEGG_REACTION:R03114|MetaCyc:CARVEOL-DEHYDROGENASE-RXN|EC:1.1.1.243									molecular_function											owl:Class	
GO:0007428	biolink:NamedThing	primary branching, open tracheal system	Formation of primary branches in the open tracheal system. These form from small groups of cells that migrate out at specific positions, organizing into tubes as they migrate. An example of this is found in Drosophila melanogaster.	tmpzr1t_l9r_go_relaxed.owl	primary tracheal branching													biological_process											owl:Class	
GO:0047345	biolink:NamedThing	ribose-5-phosphate adenylyltransferase activity	Catalysis of the reaction: D-ribose 5-phosphate + ADP + H(+) = ADP-ribose + phosphate.	tmpzr1t_l9r_go_relaxed.owl	ADP ribose phosphorylase activity|adenosine diphosphoribose phosphorylase activity|ADP:D-ribose-5-phosphate adenylyltransferase activity|ADP-ribose phosphorylase activity|ADP:ribose-5-phosphate adenylyltransferase activity				EC:2.7.7.35|MetaCyc:2.7.7.35-RXN|KEGG_REACTION:R01052|RHEA:14529									molecular_function											owl:Class	
GO:0034951	biolink:NamedThing	o-hydroxylaminobenzoate mutase activity	Catalysis of the reaction: o-hydroxylaminobenzoate = 3-hydroxyanthranilate.	tmpzr1t_l9r_go_relaxed.owl					EC:5.4.99.-|MetaCyc:RXN-8846|UM-BBD_reactionID:r1026									molecular_function											owl:Class	
GO:0018740	biolink:NamedThing	2'-hydroxybiphenyl-2-sulfinate desulfinase activity	Catalysis of the reaction: 2'-hydroxybiphenyl-2-sulfinate + H(2)O = biphenyl-2-ol + sulfite.	tmpzr1t_l9r_go_relaxed.owl	2'-hydroxybiphenyl-2-sulfinate sulfinolyase activity|DszB|2-(2-hydroxyphenyl)benzenesulfinate desulfinase activity|gene dszB-encoded hydrolase activity|2-(2-hydroxyphenyl) benzenesulfinate sulfohydrolase activity|2-(2-hydroxyphenyl) benzenesulfinate:H2O hydrolase activity|HPBS desulfinase activity|2'-hydroxybiphenyl-2-sulfinate sulfohydrolase activity|2-(2-hydroxyphenyl)benzenesulphinate hydrolase activity|2-(2-hydroxyphenyl)benzenesulfinate hydrolase activity|dibenzothiophene desulfurization enzyme B|HBPSi desulfinase activity|2-(2'-hydroxyphenyl)benzenesulfinate desulfinase activity				EC:3.13.1.3|KEGG_REACTION:R07311|MetaCyc:RXN-624|RHEA:12945|UM-BBD_enzymeID:e0216									molecular_function											owl:Class	
GO:0017042	biolink:NamedThing	glycosylceramidase activity	Catalysis of the reaction: glycosyl-N-acylsphingosine + H2O = a sugar + N-acylsphingosine.	tmpzr1t_l9r_go_relaxed.owl	glycosyl ceramide glycosylhydrolase activity|lactase-phlorizin hydrolase|phloridzin beta-glucosidase activity|cerebrosidase activity|glycosyl-N-acylsphingosine glycohydrolase activity|phloridzin glucosidase activity|phlorizin hydrolase activity|phloretin-glucosidase activity				MetaCyc:GLYCOSYLCERAMIDASE-RXN|EC:3.2.1.62									molecular_function											owl:Class	
GO:0019305	biolink:NamedThing	dTDP-rhamnose biosynthetic process	The chemical reactions and pathways resulting in the formation of dTDP-rhamnose, a substance composed of rhamnose in glycosidic linkage with deoxyribosylthymine diphosphate.	tmpzr1t_l9r_go_relaxed.owl	dTDP-rhamnose synthesis|dTDP-rhamnose anabolism|dTDP-rhamnose biosynthesis|dTDP-rhamnose formation				MetaCyc:DTDPRHAMSYN-PWY|MetaCyc:PWY-3221									biological_process											owl:Class	
GO:0034796	biolink:NamedThing	adipate-CoA ligase activity	Catalysis of the reaction: adipate + CoASH = adipyl-CoA + OH-.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r1060									molecular_function											owl:Class	
GO:0043724	biolink:NamedThing	2-keto-3-deoxygalactonate aldolase activity	Catalysis of the reaction: 2-keto-3-deoxygalactonate = D-glyceraldehyde + pyruvate.	tmpzr1t_l9r_go_relaxed.owl	KDGal aldolase activity													molecular_function											owl:Class	
GO:0062132	biolink:NamedThing	regulation of L-glutamine biosynthetic process	Any process that modulates the rate, frequency or extent of L-glutamine biosynthesis.	tmpzr1t_l9r_go_relaxed.owl								dph	2019-06-27T13:44:21Z					biological_process											owl:Class	
GO:0050579	biolink:NamedThing	vellosimine dehydrogenase activity	Catalysis of the reaction: 10-deoxysarpagine + NADP(+) = H(+) + NADPH + vellosimine.	tmpzr1t_l9r_go_relaxed.owl	10-deoxysarpagine:NADP+ oxidoreductase activity				EC:1.1.1.273|RHEA:20029|KEGG_REACTION:R05827|MetaCyc:1.1.1.273-RXN									molecular_function											owl:Class	
GO:0070462	biolink:NamedThing	plus-end specific microtubule depolymerization	The removal of tubulin heterodimers from the plus end of a microtubule.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0015218	biolink:NamedThing	pyrimidine nucleotide transmembrane transporter activity	Enables the transfer of a pyrimidine nucleotide, any compound consisting of a pyrimidine nucleoside esterified with (ortho)phosphate, from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1905177	biolink:NamedThing	tracheary element differentiation	The process in which a relatively unspecialized cell acquires the specialized features of a tracheary element.	tmpzr1t_l9r_go_relaxed.owl								tb	2016-05-04T22:14:33Z					biological_process											owl:Class	
GO:0061617	biolink:NamedThing	MICOS complex	Mitochondrial inner membrane complex involved in maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. In Saccharomyces cerevisiae the complex has six subunits: MIC10, MIC12, MIC19, MIC26, MIC27, and MIC60.	tmpzr1t_l9r_go_relaxed.owl	mitochondrial contact site and cristae organizing system|Fcj1 complex|MINOS complex|MitOS complex							dph	2014-04-14T07:18:13Z					cellular_component											owl:Class	
GO:0015612	biolink:NamedThing	ABC-type L-arabinose transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + L-arabinose(out) -> ADP + phosphate + L-arabinose(in).	tmpzr1t_l9r_go_relaxed.owl	L-arabinose-importing ATPase activity|L-arabinose porter activity				EC:7.5.2.13|MetaCyc:ABC-2-RXN|EC:7.5.2.12|RHEA:30007									molecular_function											owl:Class	
GO:0050300	biolink:NamedThing	aminoglycoside 6-kinase activity	Catalysis of the reaction: ATP + streptomycin = ADP + 2 H(+) + streptomycin 6-phosphate.	tmpzr1t_l9r_go_relaxed.owl	streptomycin 6-kinase (phosphorylating)|SM 6-kinase activity|streptidine kinase activity|streptomycin 6-O-phosphotransferase activity|streptomycin 6-phosphotransferase activity|streptidine kinase (phosphorylating)|ATP:streptomycin 6-phosphotransferase activity|APH(6) activity|streptomycin 6-kinase activity				MetaCyc:STREPTOMYCIN-6-KINASE-RXN|EC:2.7.1.72|KEGG_REACTION:R02225|RHEA:22268									molecular_function											owl:Class	
GO:1902343	biolink:NamedThing	regulation of maltose transport	Any process that modulates the frequency, rate or extent of maltose transport.	tmpzr1t_l9r_go_relaxed.owl								dph	2013-08-01T17:16:18Z					biological_process											owl:Class	
GO:0071204	biolink:NamedThing	histone pre-mRNA 3'end processing complex	A ribonucleoprotein that binds to specific sites in, and is required for cleavage of, the 3'-end of histone pre-mRNAs. The complex contains the U7 snRNP and additional proteins, including the stem-loop binding protein (SLBP) and the exonuclease 3'hExo/Eri-1.	tmpzr1t_l9r_go_relaxed.owl	histone 3'end pre-mRNA complex							mah	2009-11-25T11:11:02Z					cellular_component											owl:Class	
GO:0002306	biolink:NamedThing	CD4-positive gamma-delta intraepithelial T cell differentiation	The process in which a precursor cell type acquires the specialized features of a CD4-positive, gamma-delta intraepithelial T cell. Intraepithelial T cells are found among epithelial cells in mucosal areas and have distinct phenotypes and developmental pathways.	tmpzr1t_l9r_go_relaxed.owl	CD4-positive, gamma-delta intraepithelial T-cell differentiation|CD4-positive, gamma-delta intraepithelial T-lymphocyte differentiation|CD4-positive, gamma-delta intraepithelial T cell development|CD4-positive, gamma-delta intraepithelial T lymphocyte differentiation					Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.								biological_process											owl:Class	
GO:0035087	biolink:NamedThing	siRNA loading onto RISC involved in RNA interference	The transfer of small interfering RNA molecules (siRNAs) from the Dicer family of enzymes that cleave the double-stranded RNA, onto the nuclease-containing RNA-initiated silencing complex (RISC), in the context of RNA interference.	tmpzr1t_l9r_go_relaxed.owl	RNA interference, siRNA loading onto RISC													biological_process											owl:Class	
GO:0019561	biolink:NamedThing	anaerobic phenylalanine oxidation	The chemical reactions and pathways resulting in the breakdown of phenylalanine under anaerobic conditions; occurs via the intermediates phenylpyruvate and phenylacetaldehyde.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:ANAPHENOXI-PWY									biological_process											owl:Class	
GO:0102692	biolink:NamedThing	benzyladenine UDP glycosyltransferase activity	Catalysis of the reaction: UDP-alpha-D-glucose + N-benzyladenine <=> H+ + N-benzyl-9-(alpha-D-glucosyl)adenine + UDP.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-4730									molecular_function											owl:Class	
GO:0031899	biolink:NamedThing	chromoplast inner membrane	The inner, i.e. lumen-facing, lipid bilayer of the chromoplast envelope; also faces the chromoplast stroma.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0042618	biolink:NamedThing	poly-hydroxybutyrate metabolic process	The chemical reactions and pathways involving poly-hydroxybutyrate (PHB), a polymer of beta-hydroxybutyrate and a common storage material of prokaryotic cells.	tmpzr1t_l9r_go_relaxed.owl	PHB metabolism|PHB metabolic process|poly-hydroxybutyrate metabolism													biological_process											owl:Class	
GO:0015143	biolink:NamedThing	urate transmembrane transporter activity	Enables the transfer of urate from one side of a membrane to the other. Urate is the anion of uric acid, 2,6,8-trioxypurine, the end product of purine metabolism in certain mammals and the main excretory product in uricotelic animals.	tmpzr1t_l9r_go_relaxed.owl	uric acid transmembrane transporter activity				Reactome:R-HSA-561253|Reactome:R-HSA-2872497|Reactome:R-HSA-5625210									molecular_function											owl:Class	
GO:1901702	biolink:NamedThing	salt transmembrane transporter activity	Enables the transfer of salt from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl								pr	2012-12-13T15:14:47Z					molecular_function											owl:Class	
GO:0072357	biolink:NamedThing	PTW/PP1 phosphatase complex	A protein serine/threonine phosphatase complex that contains a catalytic subunit (PPP1CA, PPP1CB or PPP1CC) and the regulatory subunits PPP1R10 (PNUTS), TOX4 and WDR82, and plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-11-15T03:32:27Z					cellular_component											owl:Class	
GO:1901253	biolink:NamedThing	negative regulation of intracellular transport of viral material	Any process that stops, prevents or reduces the frequency, rate or extent of intracellular transport of viral material.	tmpzr1t_l9r_go_relaxed.owl	inhibition of egress of virus within host cell|negative regulation of movement of virus within host cell|down regulation of viral egress|negative regulation of egress of virus within host cell|downregulation of movement of virus within host cell|down-regulation of viral egress|down-regulation of egress of virus within host cell|down regulation of movement of virus within host cell|inhibition of movement of virus within host cell|inhibition of viral egress|down regulation of egress of virus within host cell|downregulation of viral egress|negative regulation of viral egress|down-regulation of movement of virus within host cell|downregulation of egress of virus within host cell							ss	2012-08-09T05:45:47Z					biological_process											owl:Class	
GO:0047827	biolink:NamedThing	D-lysopine dehydrogenase activity	Catalysis of the reaction: D-lysopine + H(2)O + NADP(+) = L-lysine + H(+) + NADPH + pyruvate.	tmpzr1t_l9r_go_relaxed.owl	N2-(D-1-carboxyethyl)-L-lysine:NADP+ oxidoreductase (L-lysine-forming)|2-N-(D-1-carboxyethyl)-L-lysine:NADP+ oxidoreductase (L-lysine-forming)|lysopine dehydrogenase activity|D(+)-lysopine dehydrogenase activity|D-lysopine synthase activity				EC:1.5.1.16|KEGG_REACTION:R00452|MetaCyc:D-LYSOPINE-DEHYDROGENASE-RXN|RHEA:17625									molecular_function											owl:Class	
GO:0035443	biolink:NamedThing	tripeptide transmembrane transport	The directed movement of a tripeptide across a membrane by means of some agent such as a transporter or pore. A tripeptide is a compound containing three amino acids linked together by peptide bonds.	tmpzr1t_l9r_go_relaxed.owl	tripeptide membrane transport					Note that this term is not intended for use in annotating lateral movement within membranes.		bf	2010-04-13T09:20:25Z					biological_process											owl:Class	
GO:0000342	biolink:NamedThing	RNA cap 4 binding	Binding to a hypermethylated cap structure consisting of 7-methylguanosine (m(7)G) followed by four methylated nucleotides (cap 4): 7-methylguanosine-ppp-N6, N6, 2'-O-trimethyladenosine-p-2'-O-methyladenosine-p-2'-O-methylcytosine-p-N3, 2'-O-dimethyluridine Such caps are known to be found at the 5' ends of SL RNAs of trypanosomatid protozoa.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0010211	biolink:NamedThing	IAA-Leu conjugate hydrolase activity	Catalysis of the reaction: indole-3-acetyl-leucine + H2O = indole-3-acetate + L-leucine.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-2982									molecular_function											owl:Class	
GO:0021942	biolink:NamedThing	radial glia guided migration of Purkinje cell	The migration of postmitotic a Purkinje cell along radial glial cells from the ventricular zone to the Purkinje cell layer.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0140246	biolink:NamedThing	protein catabolic process at synapse	The chemical reactions and pathways resulting in the breakdown of a protein at a synapse.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/synapse/issues/210				Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.		pg	2018-07-15T10:12:51Z					biological_process											owl:Class	
GO:0052891	biolink:NamedThing	aliphatic (S)-hydroxynitrile lyase activity	Catalysis of the reaction: an aliphatic (S)-hydroxynitrile = an aliphatic aldehyde or ketone + cyanide.	tmpzr1t_l9r_go_relaxed.owl	(S)-oxynitrilase activity|hydroxynitrile lyase activity|(S)-selective hydroxynitrile lyase activity|(S)-cyanohydrin producing hydroxynitrile lyase activity|oxynitrilase activity|(S)-hydroxynitrile lyase activity|(S)-cyanohydrin carbonyl-lyase (cyanide forming) activity				EC:4.1.2.47|MetaCyc:RXN-11731									molecular_function											owl:Class	
GO:0043693	biolink:NamedThing	monoterpene biosynthetic process	The chemical reactions and pathways resulting in the formation of monoterpenes, terpenes with a C10 structure.	tmpzr1t_l9r_go_relaxed.owl	monoterpene biosynthesis													biological_process											owl:Class	
GO:0010082	biolink:NamedThing	regulation of root meristem growth	Any process involved in maintaining the size and shape of a root meristem.	tmpzr1t_l9r_go_relaxed.owl	regulation of root meristem size													biological_process											owl:Class	
GO:0010475	biolink:NamedThing	galactose-1-phosphate guanylyltransferase (GDP) activity	Catalysis of the reaction: GDP + L-galactose 1-phosphate = phosphate + GDP-galactose.	tmpzr1t_l9r_go_relaxed.owl	GDP:galactose-1-phosphate guanyltransferase activity													molecular_function											owl:Class	
GO:0033923	biolink:NamedThing	glucan 1,6-alpha-isomaltosidase activity	Catalysis of the hydrolysis of (1->6)-alpha-D-glucosidic linkages in polysaccharides, to remove successive isomaltose units from the non-reducing ends of the chains.	tmpzr1t_l9r_go_relaxed.owl	isomalto-dextranase activity|isomaltodextranase activity|exo-isomaltohydrolase activity|1,6-alpha-D-glucan isomaltohydrolase activity|G2-dextranase activity				MetaCyc:3.2.1.94-RXN|EC:3.2.1.94									molecular_function											owl:Class	
GO:0010459	biolink:NamedThing	negative regulation of heart rate	Any process that stops, prevents or reduces the frequency or rate of heart contraction.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1902933	biolink:NamedThing	isopentenol metabolic process	The chemical reactions and pathways involving isopentenol.	tmpzr1t_l9r_go_relaxed.owl	isopentenol metabolism							tt	2014-04-24T16:51:35Z					biological_process											owl:Class	
GO:0032574	biolink:NamedThing	5'-3' RNA helicase activity	Unwinding of an RNA helix in the 5' to 3' direction, driven by ATP hydrolysis.	tmpzr1t_l9r_go_relaxed.owl	ATP-dependent 5'-3' RNA helicase activity|5' to 3' RNA helicase activity|ATP-dependent 5' to 3' RNA helicase activity	https://github.com/geneontology/go-ontology/issues/21612			Reactome:R-HSA-9694265|Reactome:R-HSA-9682695							GO:0032575		molecular_function											owl:Class	
GO:0090292	biolink:NamedThing	nuclear matrix anchoring at nuclear membrane	The process in which the nuclear matrix, the dense fibrillar network lying on the inner side of the nuclear membrane, is directly or indirectly linked to the nuclear membrane.	tmpzr1t_l9r_go_relaxed.owl	nucleoskeleton anchoring at nuclear membrane							tb	2010-02-22T03:05:13Z					biological_process											owl:Class	
GO:0043578	biolink:NamedThing	nuclear matrix organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear matrix, the dense fibrillar network lying on the inner side of the nuclear membrane.	tmpzr1t_l9r_go_relaxed.owl	nuclear matrix organisation|nucleoskeleton organization|nuclear matrix organization and biogenesis													biological_process											owl:Class	
GO:0010409	biolink:NamedThing	extensin metabolic process	The chemical reactions and pathways involving extensins, a group of 60-90 kDNA hydroxyproline (Hyp)-rich glycoproteins whose polypeptide backbone consists of many repeats of structural Ser(Hyp)4-6 motifs, with heavily glycosylated 1-4 arabinose residues O-linked to contiguous stretches of Hyp residues, with most of the Ser residues being O-galactosylated.	tmpzr1t_l9r_go_relaxed.owl	extensin metabolism													biological_process											owl:Class	
GO:0010404	biolink:NamedThing	cell wall hydroxyproline-rich glycoprotein metabolic process	The chemical reactions and pathways involving a cell wall hydroxyproline-rich glycoprotein that consist of a core-protein backbone O-glycosylated by one or more complex carbohydrates.	tmpzr1t_l9r_go_relaxed.owl	cell wall hydroxyproline-rich glycoprotein metabolism													biological_process											owl:Class	
GO:0050048	biolink:NamedThing	L-leucine:2-oxoglutarate aminotransferase activity	Catalysis of the reaction: L-leucine + 2-oxoglutarate = 4-methyl-2-oxopentanoate + L-glutamate.	tmpzr1t_l9r_go_relaxed.owl	leucine-alpha-ketoglutarate transaminase activity|leucine transaminase activity|L-leucine aminotransferase activity|leucine aminotransferase activity|leucine 2-oxoglutarate transaminase activity				RHEA:18321|MetaCyc:LEUCINE-AMINOTRANSFERASE-RXN|EC:2.6.1.6									molecular_function											owl:Class	
GO:0031021	biolink:NamedThing	interphase microtubule organizing center	A microtubule organizing center found in interphase cells, which organize a longitudinal array of three to five MT bundles from the nuclear envelope during interphase. Each MT bundle is composed of two to seven MTs arranged in an antiparallel configuration, with the dynamic MT plus ends extending toward the cell tips and stable minus ends near the nucleus.	tmpzr1t_l9r_go_relaxed.owl	interphase microtubule organising center|interphase MTOC|iMTOC													cellular_component											owl:Class	
GO:2000308	biolink:NamedThing	negative regulation of tumor necrosis factor (ligand) superfamily member 11 production	Any process that stops, prevents or reduces the frequency, rate or extent of tumor necrosis factor (ligand) superfamily member 11 production.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of RANKL production|negative regulation of TNFSF11 production							mah	2011-01-17T10:44:33Z					biological_process											owl:Class	
GO:0033226	biolink:NamedThing	2-aminoethylphosphonate binding	Binding to 2-aminoethylphosphonate.	tmpzr1t_l9r_go_relaxed.owl	ciliatine binding|2-phosphonoethylamine binding													molecular_function											owl:Class	
GO:0102154	biolink:NamedThing	8C-naringenin dibenzoylmethane tautomer glucosyltransferase activity	Catalysis of the reaction: 2,4,4',6-tetrahydroxydibenzoylmethane + UDP-alpha-D-glucose <=> 8C-glucosyl-2-hydroxynaringenin + UDP + 2 H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-11685									molecular_function											owl:Class	
GO:0080013	biolink:NamedThing	(E,E)-geranyllinalool synthase activity	Catalysis of the reaction: all-trans-geranyl-geranyl diphosphate + H2O = (E,E)-geranyllinalool + diphosphate.	tmpzr1t_l9r_go_relaxed.owl					RHEA:38155|MetaCyc:RXN-10441									molecular_function											owl:Class	
GO:0090058	biolink:NamedThing	metaxylem development	The process whose specific outcome is the progression of the metaxylem over time, from its formation to the mature structure. The metaxylem is the part of the primary xylem that differentiates after the protoxylem and before the secondary xylem, if any of the latter is formed.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-08-11T03:05:15Z					biological_process											owl:Class	
GO:0030626	biolink:NamedThing	U12 snRNA binding	Binding to a U12 small nuclear RNA (U12 snRNA).	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1904414	biolink:NamedThing	positive regulation of cardiac ventricle development	Any process that activates or increases the frequency, rate or extent of cardiac ventricle development.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of cardiac ventricle development|up regulation of cardiac ventricle development|upregulation of cardiac ventricle development|activation of cardiac ventricle development							sl	2015-06-25T19:52:27Z					biological_process											owl:Class	
GO:0050429	biolink:NamedThing	calcium-dependent phospholipase C activity	Catalysis of the reaction: a phosphatidylcholine + H2O = 1,2-diacylglycerol + choline phosphate. This reaction requires Ca2+.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0006212	biolink:NamedThing	uracil catabolic process	The chemical reactions and pathways resulting in the breakdown of uracil, 2,4-dioxopyrimidine, one of the pyrimidine bases occurring in RNA, but not in DNA.	tmpzr1t_l9r_go_relaxed.owl	uracil catabolism|uracil breakdown|uracil degradation													biological_process											owl:Class	
GO:0050548	biolink:NamedThing	trans-feruloyl-CoA hydratase activity	Catalysis of the reaction: trans-feruloyl-CoA + H2O = 4-hydroxy-3-methoxyphenyl-beta-hydroxypropionyl-CoA.	tmpzr1t_l9r_go_relaxed.owl	4-hydroxy-3-methoxyphenyl-beta-hydroxypropanoyl-CoA hydro-lyase (trans-feruloyl-CoA-forming)|trans-feruloyl-CoA hydro-lyase activity				EC:4.2.1.101|MetaCyc:4.2.1.101-RXN|RHEA:14517									molecular_function											owl:Class	
GO:0090736	biolink:NamedThing	MATH domain binding	Binding to a meprin and TRAF homology (MATH) domain.	tmpzr1t_l9r_go_relaxed.owl								tb	2017-02-06T17:08:28Z					molecular_function											owl:Class	
GO:0033540	biolink:NamedThing	fatty acid beta-oxidation using acyl-CoA oxidase	A fatty acid beta-oxidation pathway in which the initial step, which converts an acyl-CoA to a trans-2-enoyl-CoA, is catalyzed by acyl-CoA oxidase; the electrons removed by oxidation pass directly to oxygen and produce hydrogen peroxide, which is cleaved by peroxisomal catalases. Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and ends when only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively).	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:PWY-5136									biological_process											owl:Class	
GO:0061533	biolink:NamedThing	norepinephrine secretion, neurotransmission	The regulated release of norepinephrine by a cell, in which the norepinephrine acts as a neurotransmitter.	tmpzr1t_l9r_go_relaxed.owl	noradrenaline secretion, neurotransmission							dph	2013-06-21T16:05:08Z					biological_process											owl:Class	
GO:0072003	biolink:NamedThing	kidney rudiment formation	The developmental process pertaining to the initial formation of a kidney rudiment from unspecified parts. A kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine.	tmpzr1t_l9r_go_relaxed.owl	kidney anlage formation							mah	2010-01-25T11:18:58Z					biological_process											owl:Class	
GO:0047613	biolink:NamedThing	aconitate decarboxylase activity	Catalysis of the reaction: cis-aconitate + H(+) = CO(2) + itaconate.	tmpzr1t_l9r_go_relaxed.owl	cis-aconitic decarboxylase activity|cis-aconitate carboxy-lyase activity|CAD activity|cis-aconitate carboxy-lyase (itaconate-forming)				MetaCyc:ACONITATE-DECARBOXYLASE-RXN|KEGG_REACTION:R02243|RHEA:15253|EC:4.1.1.6									molecular_function											owl:Class	
GO:0036261	biolink:NamedThing	7-methylguanosine cap hypermethylation	Hypermethylation of the 7-(mono)methylguanosine (m(7)G) cap structure at the 2' position of the guanosine residue to convert a mono-methylated cap to a 2,2,7-trimethylguanosine cap structure. This type of cap modification occurs on small nuclear RNAs (snRNAs) and small nucleolar RNAs (snoRNAs) and is dependent on prior guanine-N7 methylation.	tmpzr1t_l9r_go_relaxed.owl	2,2,7-trimethylguanosine cap formation|hypermethylation of snRNA cap|snRNA capping|TMG cap formation|hypermethylation of snoRNA cap|conversion of m(7)G to m(3)G|snoRNA capping|m(7)G cap hypermethylation							bf	2012-06-15T02:21:39Z					biological_process											owl:Class	
GO:0018818	biolink:NamedThing	acetylene hydratase activity	Catalysis of the reaction: acetaldehyde = acetylene + H(2)O.	tmpzr1t_l9r_go_relaxed.owl	acetaldehyde hydro-lyase activity|AH|AHy				MetaCyc:R141-RXN|UM-BBD_reactionID:r0591|EC:4.2.1.112|RHEA:17885|KEGG_REACTION:R05380									molecular_function											owl:Class	
GO:0051501	biolink:NamedThing	diterpene phytoalexin metabolic process	The chemical reactions and pathways involving diterpene phytoalexins, a class of diterpene formed in plants in response to fungal infection, physical damage, chemical injury, or a pathogenic process; they are sometimes referred to as plant antibiotics. Diterpenes are unsaturated hydrocarbons containing 20 carbon atoms and 4 branched methyl groups and are made up of isoprenoid units.	tmpzr1t_l9r_go_relaxed.owl	diterpene phytoalexin metabolism													biological_process											owl:Class	
GO:0035069	biolink:NamedThing	larval midgut histolysis	The stage-specific break down of the larval midgut during Drosophila metamorphosis, to allow replacement of larval structures by tissues and structures that form the adult fly.	tmpzr1t_l9r_go_relaxed.owl	larval midgut regression													biological_process											owl:Class	
GO:0015374	biolink:NamedThing	neutral, basic amino acid:sodium:chloride symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: neutral/basic amino acid(out) + Na+(out) + Cl-(out) = neutral/basic amino acid(in) + Na+(in) + Cl-(in).	tmpzr1t_l9r_go_relaxed.owl	neutral, cationic amino acid:sodium:chloride symporter activity													molecular_function											owl:Class	
GO:0015553	biolink:NamedThing	xanthosine transmembrane transporter activity	Enables the transfer of xanthosine, xanthine riboside, from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0071996	biolink:NamedThing	glutathione transmembrane import into vacuole	The directed movement of glutathione into the vacuole across the vacuolar membrane.	tmpzr1t_l9r_go_relaxed.owl	glutathione transport into vacuole							mah	2010-10-25T02:12:01Z					biological_process											owl:Class	
GO:0033758	biolink:NamedThing	clavaminate synthase activity	Catalysis of the reactions: deoxyamidinoproclavaminate + 2-oxoglutarate + O2 = amidinoproclavaminate + succinate + CO2 + H2O; proclavaminate + 2-oxoglutarate + O2 = dihydroclavaminate + succinate + CO2 + 2 H2O; and dihydroclavaminate + 2-oxoglutarate + O2 = clavaminate + succinate + CO2 + 2 H2O.	tmpzr1t_l9r_go_relaxed.owl	clavaminic acid synthase activity|clavaminate synthase 2 activity|deoxyamidinoproclavaminate,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating) activity				EC:1.14.11.21|RHEA:20021|MetaCyc:1.14.11.21-RXN									molecular_function											owl:Class	
GO:0050462	biolink:NamedThing	N-acetylneuraminate synthase activity	Catalysis of the reaction: phosphoenolpyruvate + N-acetyl-D-mannosamine + H2O = phosphate + N-acetylneuraminate.	tmpzr1t_l9r_go_relaxed.owl	(NANA)condensing enzyme activity|NeuAc synthase activity|N-acetylneuraminate pyruvate-lyase (pyruvate-phosphorylating) activity|phosphoenolpyruvate:N-acetyl-D-mannosamine C-(1-carboxyvinyl)transferase (phosphate-hydrolysing, 2-carboxy-2-oxoethyl-forming)|N-acetylneuraminic acid synthase activity				EC:2.5.1.56|RHEA:19273|MetaCyc:N-ACETYLNEURAMINATE-SYNTHASE-RXN									molecular_function											owl:Class	
GO:0046003	biolink:NamedThing	negative regulation of syncytial blastoderm mitotic cell cycle	Any process that stops, prevents or reduces the rate or extent of progression through the syncytial blastoderm mitotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of syncytial blastoderm cell cycle progression|inhibition of progression through syncytial blastoderm mitotic cell cycle|negative regulation of progression through syncytial blastoderm mitotic cell cycle|down regulation of progression through syncytial blastoderm mitotic cell cycle|downregulation of progression through syncytial blastoderm mitotic cell cycle|down-regulation of progression through syncytial blastoderm mitotic cell cycle													biological_process											owl:Class	
GO:0106077	biolink:NamedThing	histone succinylation	The modification of a histone by the addition of an succinyl group.	tmpzr1t_l9r_go_relaxed.owl								hjd	2017-12-15T18:27:16Z					biological_process											owl:Class	
GO:0031887	biolink:NamedThing	lipid droplet transport along microtubule	The directed movement of a lipid droplet along a microtubule, mediated by motor proteins.	tmpzr1t_l9r_go_relaxed.owl	lipid particle transport along microtubule|adiposome transport along microtubule|lipid body transport along microtubule													biological_process											owl:Class	
GO:0080075	biolink:NamedThing	spermidine:feruloyl CoA N-acyltransferase activity	Catalysis of the transfer of a feruloyl group to a nitrogen atom on the spermidine molecule.	tmpzr1t_l9r_go_relaxed.owl								dhl	2009-04-13T04:17:50Z					molecular_function											owl:Class	
GO:0102657	biolink:NamedThing	1-18:1-2-16:0-monogalactosyldiacylglycerol palmitoyl-lipid 7-desaturase activity	Catalysis of the reaction: 1-18:1-2-16:0-monogalactosyldiacylglycerol + O2 + a reduced electron acceptor = 1-18:1-2-16:1-monogalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor.	tmpzr1t_l9r_go_relaxed.owl					EC:1.14.19.42|MetaCyc:RXN-1728									molecular_function											owl:Class	
GO:1990277	biolink:NamedThing	parasexual conjugation with cellular fusion	A conjugation process that results in the union of cellular and genetic information from compatible mating types, without the formation of zygotes. An example of this process is found in Candida albicans.	tmpzr1t_l9r_go_relaxed.owl	mating							pr	2014-01-28T10:30:20Z					biological_process											owl:Class	
GO:0017171	biolink:NamedThing	serine hydrolase activity	Catalysis of the hydrolysis of a substrate by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine).	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0042673	biolink:NamedThing	regulation of retinal cone cell fate specification	Any process that mediates the specification of a cell into a retinal cone cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1900625	biolink:NamedThing	positive regulation of monocyte aggregation	Any process that activates or increases the frequency, rate or extent of monocyte aggregation.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of monocyte aggregation|up-regulation of mononuclear phagocyte aggregation|activation of mononuclear phagocyte aggregation|upregulation of mononuclear phagocyte aggregation|activation of monocyte aggregation|upregulation of monocyte aggregation|up regulation of monocyte aggregation|positive regulation of mononuclear phagocyte aggregation|up regulation of mononuclear phagocyte aggregation							vk	2012-05-21T01:07:44Z					biological_process											owl:Class	
GO:0002558	biolink:NamedThing	type I hypersensitivity mediated by mast cells	An inflammatory response driven by antigen recognition by antibodies bound to Fc receptors on mast cells, occurring within minutes after exposure of a sensitized individual to the antigen, and leading to the release of a variety of inflammatory mediators such as histamines.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0047592	biolink:NamedThing	5-pyridoxate dioxygenase activity	Catalysis of the reaction: 5-pyridoxate + NADPH + O(2) = 2-(acetamidomethylene)-3-(hydroxymethyl)succinate) + NADP(+).	tmpzr1t_l9r_go_relaxed.owl	5-pyridoxate oxidase activity	https://github.com/geneontology/go-ontology/issues/21412			EC:1.14.13.241|RHEA:11152|KEGG_REACTION:R04570|MetaCyc:5-PYRIDOXATE-DIOXYGENASE-RXN	Formerly EC:1.14.12.5.								molecular_function											owl:Class	
GO:0097124	biolink:NamedThing	cyclin A2-CDK2 complex	A protein complex consisting of cyclin A2 and cyclin-dependent kinase 2 (CDK2). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner.	tmpzr1t_l9r_go_relaxed.owl								pr	2011-08-01T01:44:19Z					cellular_component											owl:Class	
GO:0010177	biolink:NamedThing	2-(2'-methylthio)ethylmalate synthase activity	Catalysis of the reaction: 2-oxo-4-methylthiobutanoate + acetyl-CoA + H2O = 2-(2'-methylthio)ethylmalic-acid + coenzyme A + H+.	tmpzr1t_l9r_go_relaxed.owl	methylthioalkylmalate synthase activity				MetaCyc:RXN-2202|EC:2.3.3.17									molecular_function											owl:Class	
GO:0102732	biolink:NamedThing	myo-inositol-1,2,3,4,6-heptakisphosphate 5-kinase activity	Catalysis of the reaction: 1L-myo-inositol 1,2,3,4,6-pentakisphosphate(10-) + ATP = H+ + myo-inositol hexakisphosphate(12-) + ADP.	tmpzr1t_l9r_go_relaxed.owl					EC:2.7.1.140|MetaCyc:RXN-7186									molecular_function											owl:Class	
GO:1990217	biolink:NamedThing	suppression by symbiont of host phytoalexin production	Any process in which a symbiont stops, prevents, or reduces the frequency, rate or extent of phytoalexin production in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	negative regulation by symbiont of host phytoalexin production							ml	2013-10-10T15:49:33Z					biological_process											owl:Class	
GO:0044231	biolink:NamedThing	host cell presynaptic membrane	A specialized area of membrane of the host axon terminal that faces the plasma membrane of the host neuron or muscle fiber with which the axon terminal establishes a synaptic junction; many host synaptic junctions exhibit structural presynaptic characteristics, such as conical, electron-dense internal protrusions, that distinguish it from the remainder of the axon plasma membrane.	tmpzr1t_l9r_go_relaxed.owl	other organism presynaptic membrane|other organism pre-synaptic membrane|host cell pre-synaptic membrane							jl	2009-12-08T02:11:18Z			GO:0072556		cellular_component											owl:Class	
GO:0090505	biolink:NamedThing	epiboly involved in wound healing	The expansion of one cell sheet over other cells involved in wound healing.	tmpzr1t_l9r_go_relaxed.owl								tb	2012-10-22T12:38:51Z					biological_process											owl:Class	
GO:0060840	biolink:NamedThing	artery development	The progression of the artery over time, from its initial formation to the mature structure. An artery is a blood vessel that carries blood away from the heart to a capillary bed.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-08-12T10:10:51Z					biological_process											owl:Class	
GO:0031702	biolink:NamedThing	type 1 angiotensin receptor binding	Binding to a type 1 angiotensin receptor.	tmpzr1t_l9r_go_relaxed.owl	AT1 receptor binding|type 1 angiotensin receptor ligand													molecular_function											owl:Class	
GO:0031356	biolink:NamedThing	intrinsic component of chloroplast inner membrane	The component of the chloroplast inner membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.	tmpzr1t_l9r_go_relaxed.owl	intrinsic to chloroplast inner membrane													cellular_component											owl:Class	
GO:0033188	biolink:NamedThing	sphingomyelin synthase activity	Catalysis of the reaction: 1,2-diacyl-sn-glycero-3-phosphocholine + ceramide = 1,2-diacyl-sn-glycerol + sphingomyelin.	tmpzr1t_l9r_go_relaxed.owl	SMS1|ceramide:phosphatidylcholine cholinephosphotransferase activity|phosphatidylcholine:ceramide cholinephosphotransferase activity|SM synthase activity|SMS2				Reactome:R-HSA-429786|KEGG_REACTION:R08969|EC:2.7.8.27|RHEA:18765|MetaCyc:2.7.8.27-RXN|Reactome:R-HSA-429798									molecular_function											owl:Class	
GO:0034042	biolink:NamedThing	5-formyluracil DNA N-glycosylase activity	Catalysis of the removal of 5-formyluracil bases by cleaving the N-C1' glycosidic bond between the oxidized pyrimidine and the deoxyribose sugar.	tmpzr1t_l9r_go_relaxed.owl	5-foU DNA N-glycosylase activity													molecular_function											owl:Class	
GO:1905805	biolink:NamedThing	excitatory synapse pruning	The disaggregation of an excitatory synapse into its constituent components.	tmpzr1t_l9r_go_relaxed.owl	synapse elimination|synapse disassembly|synapse removal|synapse clearance							tb	2017-01-11T22:03:06Z					biological_process											owl:Class	
GO:0044669	biolink:NamedThing	sodium:galactoside symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sodium(out)+ galactoside(out) = sodium(in) + galactoside(in).	tmpzr1t_l9r_go_relaxed.owl								jl	2012-08-08T12:55:32Z					molecular_function											owl:Class	
GO:0097505	biolink:NamedThing	Rad6-Rad18 complex	A ubiquitin ligase complex found to be involved in post-replicative bypass of UV-damaged DNA and UV mutagenesis. In S. cerevisiae, the complex contains the ubiquitin conjugating enzyme Rad6 and Rad18, a protein containing a RING finger motif and a nucleotide binding motif. The yeast Rad6-Rad18 heterodimer has ubiquitin conjugating activity, binds single-stranded DNA, and possesses single-stranded DNA-dependent ATPase activity.	tmpzr1t_l9r_go_relaxed.owl								pr	2013-09-26T13:42:58Z					cellular_component											owl:Class	
GO:1905761	biolink:NamedThing	SCF ubiquitin ligase complex binding	Binding to a SCF ubiquitin ligase complex.	tmpzr1t_l9r_go_relaxed.owl	cullin-RING ligase 1 binding|SCF complex substrate recognition subunit binding|CRL1 complex binding|CDL1 complex binding|Cul1-RING ubiquitin ligase complex binding|Skp1/Cul1/F-box protein complex binding|SCF complex binding							dph	2016-12-14T15:08:12Z					molecular_function											owl:Class	
GO:0102759	biolink:NamedThing	campestanol hydroxylase activity	Catalysis of the reaction: H+ + campestanol + O2 + NADPH <=> 6-deoxycathasterone + H2O + NADP.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-773									molecular_function											owl:Class	
GO:0043265	biolink:NamedThing	ectoplasm	Granule free cytoplasm, lying immediately below the plasma membrane.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0031858	biolink:NamedThing	pituitary adenylate cyclase-activating polypeptide receptor binding	Binding to a pituitary adenylate cyclase-activating polypeptide receptor.	tmpzr1t_l9r_go_relaxed.owl	PACAP receptor binding|pituitary adenylate cyclase-activating peptide receptor ligand|pituitary adenylate cyclase activating peptide receptor binding													molecular_function											owl:Class	
GO:0098881	biolink:NamedThing	exocytic insertion of neurotransmitter receptor to plasma membrane	The exocytic fusion of neurotransmitter receptor-containing vesicles with plasma membrane, resulting in the integration of neurotransmitter receptors into the plasma membrane. This process includes tethering and docking steps that prepare vesicles for fusion.	tmpzr1t_l9r_go_relaxed.owl	neurotransmitter receptor insertion													biological_process											owl:Class	
GO:0047263	biolink:NamedThing	N-acylsphingosine galactosyltransferase activity	Catalysis of the reaction: ceramide + UDP-galactose = D-galactosylceramide + UDP.	tmpzr1t_l9r_go_relaxed.owl	uridine diphosphogalactose-acylsphingosine galactosyltransferase activity|UDP galactose-N-acylsphingosine galactosyltransferase activity|UDP-galactose:N-acylsphingosine D-galactosyltransferase activity|UDPgalactose:N-acylsphingosine D-galactosyltransferase activity				MetaCyc:2.4.1.47-RXN|RHEA:13093|Reactome:R-HSA-6785933|EC:2.4.1.47									molecular_function											owl:Class	
GO:0033561	biolink:NamedThing	regulation of water loss via skin	A process that modulates the rate or extent of water loss from an organism via the skin.	tmpzr1t_l9r_go_relaxed.owl	skin barrier function													biological_process											owl:Class	
GO:0010775	biolink:NamedThing	meiotic strand invasion involved in meiotic gene conversion	The cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate resulting in meiotic recombination.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0043890	biolink:NamedThing	N-acetylgalactosamine-6-sulfatase activity	Catalysis of the hydrolysis of the 6-sulfate groups of the N-acetyl-D-galactosamine 6-sulfate units of chondroitin sulfate and of the D-galactose 6-sulfate units of keratan sulfate.	tmpzr1t_l9r_go_relaxed.owl	acetylgalactosamine 6-sulfatase activity|chondroitinsulfatase|chondroitinase|N-acetylgalactosamine-6-sulfate sulfatase activity|galactose-6-sulfate sulfatase activity|N-acetyl-D-galactosamine-6-sulfate 6-sulfohydrolase activity|N-acetylgalactosamine 6-sulfatase activity|chondroitin sulfatase				EC:3.1.6.4|Reactome:R-HSA-2263490|MetaCyc:3.1.6.4-RXN|Reactome:R-HSA-1630304									molecular_function											owl:Class	
GO:0009375	biolink:NamedThing	ferredoxin hydrogenase complex	An enzyme complex that catalyzes the oxidation of reduced ferredoxin. Hydrogenase contains iron-sulfur clusters, and some contain nickel; it can use molecular hydrogen for the reduction of a variety of substances.	tmpzr1t_l9r_go_relaxed.owl	hydrogenase complex													cellular_component											owl:Class	
GO:0051269	biolink:NamedThing	alpha-keto ester reductase activity	Catalysis of the reaction: alpha-keto ester + 2 H+ (from donor) = (R)-hydroxy ester. Alpha-keto esters are of the form R(1)-CO-CO-O-R(2), where the R groups may be aromatic or aliphatic.	tmpzr1t_l9r_go_relaxed.owl					EC:1.2.-.-									molecular_function											owl:Class	
GO:0102454	biolink:NamedThing	cyanidin 3-O-galactosyltransferase activity	Catalysis of the reaction: cyanidin + UDP-D-galactose = cyanidin 3-O-beta-D-galactoside betaine + UDP.	tmpzr1t_l9r_go_relaxed.owl					EC:2.4.1.294|MetaCyc:RXN-13960|RHEA:35631									molecular_function											owl:Class	
GO:0018684	biolink:NamedThing	2,5-diketocamphane 1,2-monooxygenase	Catalysis of the reaction: 1R,4R)-bornane-2,5-dione + FMNH2 + O2 = (1R,4R)-5-oxo-1,2-campholide + FMN + H+ + H2O.	tmpzr1t_l9r_go_relaxed.owl	(+)-camphor,reduced-rubredoxin:oxygen oxidoreductase (1,2-lactonizing)|camphor ketolactonase I activity|camphor 1,2-monooxygenase activity|2,5-diketocamphane lactonizing enzyme activity	https://github.com/geneontology/go-ontology/issues/21412			RHEA:34415|UM-BBD_enzymeID:e0302|EC:1.14.14.108|MetaCyc:CAMPHOR-12-MONOOXYGENASE-RXN	Formerly EC:1.14.15.2.								molecular_function											owl:Class	
GO:0097142	biolink:NamedThing	PUMA-BCL-2 complex	A heterodimeric protein complex consisting of PUMA and BCL-2, members of the Bcl-2 family of anti- and proapoptotic regulators.	tmpzr1t_l9r_go_relaxed.owl								pr	2011-08-02T01:43:18Z					cellular_component											owl:Class	
GO:0004425	biolink:NamedThing	indole-3-glycerol-phosphate synthase activity	Catalysis of the reaction: 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate = 1-(indol-3-yl)glycerol 3-phosphate + CO2 + H2O.	tmpzr1t_l9r_go_relaxed.owl	indoleglycerol phosphate synthase activity|1-(2-carboxyphenylamino)-1-deoxy-D-ribulose-5-phosphate carboxy-lyase [cyclizing; 1-C-(3-indolyl)-glycerol-3-phosphate-forming]|indoleglycerol phosphate synthetase activity|indole-3-glycerophosphate synthase activity|1-(2-carboxyphenylamino)-1-deoxy-D-ribulose-5-phosphate carboxy-lyase (cyclizing)				MetaCyc:IGPSYN-RXN|RHEA:23476|EC:4.1.1.48									molecular_function											owl:Class	
GO:0061977	biolink:NamedThing	hip joint articular cartilage development	The process whose specific outcome is the progression of hip joint articular cartilage over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl								dph	2018-02-12T20:03:22Z					biological_process											owl:Class	
GO:0062119	biolink:NamedThing	LinE complex	A protein complex that associates with chromatin to form linear elements in fission yeast. In S. pombe, the LinE complex contains four main structural components (Rec10, Rec25, Rec27, and Mug20) and other associated proteins.	tmpzr1t_l9r_go_relaxed.owl								dph	2019-03-19T14:00:26Z					cellular_component											owl:Class	
GO:1990576	biolink:NamedThing	G protein-coupled glucose receptor activity	Combining with an extracellular glucose molecule and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.	tmpzr1t_l9r_go_relaxed.owl	G-protein coupled glucose receptor activity							al	2014-12-08T03:15:12Z					molecular_function											owl:Class	
GO:0018588	biolink:NamedThing	tri-n-butyltin dioxygenase activity	Catalysis of the reaction: tri-n-butyltin + O2 + 2 H+ + 2 e- = H2O + beta-hydroxybutyldibutyltin.	tmpzr1t_l9r_go_relaxed.owl	TBT dioxygenase activity				UM-BBD_reactionID:r0643									molecular_function											owl:Class	
GO:0061835	biolink:NamedThing	ventral surface of cell	The surface of a migrating cell that is in contact with the substratum or cell layer.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0009378	biolink:NamedThing	four-way junction helicase activity	Unwinding a DNA helix of DNA containing four-way junctions, including Holliday junctions, driven by ATP hydrolysis.	tmpzr1t_l9r_go_relaxed.owl	ATP-dependent Holliday junction helicase activity|Holliday junction helicase activity|ATP-dependent four-way junction DNA helicase activity|ATP-dependent four-way junction helicase activity							pr	2013-08-07T13:36:54Z			GO:1990163		molecular_function											owl:Class	
GO:0005366	biolink:NamedThing	myo-inositol:proton symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: myo-inositol(out) + H+(out) = myo-inositol(in) + H+(in).	tmpzr1t_l9r_go_relaxed.owl	hydrogen/myo-inositol transporter activity|myo-inositol:hydrogen symporter activity				Reactome:R-HSA-429101|RHEA:60364									molecular_function											owl:Class	
GO:0014732	biolink:NamedThing	skeletal muscle atrophy	A process, occurring in skeletal muscle, that is characterized by a decrease in protein content, fiber diameter, force production and fatigue resistance in response to different conditions such as starvation, aging and disuse.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0046966	biolink:NamedThing	thyroid hormone receptor binding	Binding to a thyroid hormone receptor.	tmpzr1t_l9r_go_relaxed.owl	ligand-dependent thyroid hormone receptor interactor activity													molecular_function											owl:Class	
GO:0036428	biolink:NamedThing	adenosylcobinamide kinase (GTP-specific) activity	Catalysis of the reaction: adenosylcobinamide + GTP = adenosylcobinamide phosphate + GDP + H+.	tmpzr1t_l9r_go_relaxed.owl					KEGG_REACTION:R06558|MetaCyc:RXN-14063|RHEA:15765			bf	2013-09-16T14:05:39Z					molecular_function											owl:Class	
GO:0140570	biolink:NamedThing	extraction of mislocalized protein from mitochondrial outer membrane	The removal of a mislocalized protein from the mitochondrial outer membrane.	tmpzr1t_l9r_go_relaxed.owl	extraction of mislocalized protein from outer mitochondrion membrane	https://github.com/geneontology/go-ontology/issues/20237						pg	2020-12-15T07:37:12Z					biological_process											owl:Class	
GO:0050041	biolink:NamedThing	lactate aldolase activity	Catalysis of the reaction: (S)-lactate = acetaldehyde + formate.	tmpzr1t_l9r_go_relaxed.owl	(S)-lactate acetaldehyde-lyase (formate-forming)|(S)-lactate acetaldehyde-lyase activity|lactate synthase activity				KEGG_REACTION:R00753|MetaCyc:LACTATE-ALDOLASE-RXN|RHEA:17909|EC:4.1.2.36									molecular_function											owl:Class	
GO:0021974	biolink:NamedThing	trigeminothalamic tract morphogenesis	Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in spinal cord towards target cells in the thalamus. This axonal process is a member of those that make up the trigeminothalamic tract, one of the major routes of nociceptive and temperature signaling from the face.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0008962	biolink:NamedThing	phosphatidylglycerophosphatase activity	Catalysis of the reaction: phosphatidylglycerophosphate + H2O = phosphatidylglycerol + phosphate.	tmpzr1t_l9r_go_relaxed.owl	PGP phosphatase activity|phosphatidylglycerol phosphate phosphatase activity|phosphatidylglycerophosphate phosphohydrolase activity|phosphatidylglycerol phosphatase activity				RHEA:16725|EC:3.1.3.27|MetaCyc:PGPPHOSPHA-RXN|Reactome:R-HSA-1483197									molecular_function											owl:Class	
GO:0006028	biolink:NamedThing	galactosaminoglycan catabolic process	The chemical reactions and pathways resulting in the breakdown of galactosaminoglycans, any of a group of polysaccharides that contain amino sugars derived from the galactose.	tmpzr1t_l9r_go_relaxed.owl	galactosaminoglycan degradation|galactosaminoglycan breakdown|galactosaminoglycan catabolism													biological_process											owl:Class	
GO:0046350	biolink:NamedThing	galactosaminoglycan metabolic process	The chemical reactions and pathways involving galactosaminoglycans, any one of a group of polysaccharides that contain amino sugars derived from the galactose.	tmpzr1t_l9r_go_relaxed.owl	galactosaminoglycan metabolism													biological_process											owl:Class	
GO:0070940	biolink:NamedThing	dephosphorylation of RNA polymerase II C-terminal domain	The process of removing a phosphate group from an amino acid residue in the C-terminal domain of RNA polymerase II. Some dephosphorylation occurs during transcription while some may occur after the enzyme is released from the template in order to prepare it for the beginning of the transcription cycle again. RNA polymerase II with little or no phosphorylation is referred to as the hypophosphorylated or II(A) form.	tmpzr1t_l9r_go_relaxed.owl	CTD domain dephosphorylation of RNA polymerase II|generation of hypophosphorylated CTD of RNA polymerase II|generation of II(A) form of RNA polymerase II							mah	2009-09-29T04:34:14Z					biological_process											owl:Class	
GO:0035488	biolink:NamedThing	cytosine/thymine mispair binding	Binding to a double-stranded DNA region containing a C/T mispair.	tmpzr1t_l9r_go_relaxed.owl	T/C mispair binding|C/T mispair binding|thymine/cytosine mispair binding							bf	2010-04-23T10:57:13Z					molecular_function											owl:Class	
GO:0150058	biolink:NamedThing	amylin receptor complex 3	A G protein-coupled receptor complex that serves as a receptor for amylin polypeptide (AMY) and consists of a calcitonin receptor (CTR/CALCR) and a receptor activity-modifying protein (RAMP) 3. Amylin receptor complex 3 (AMY3) also serves as a receptor for the amyloid-beta complex. Ligand binding to AMY3 results in increased cytosolic calcium ion levels and in activation on multiple intracellular signalling pathways.	tmpzr1t_l9r_go_relaxed.owl	AMY3 complex							bc	2018-06-21T10:54:00Z					cellular_component											owl:Class	
GO:0010042	biolink:NamedThing	response to manganese ion	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a manganese ion stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to manganese													biological_process											owl:Class	
GO:0010509	biolink:NamedThing	polyamine homeostasis	Any biological process involved in the maintenance of an internal steady state of a polyamine.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0018734	biolink:NamedThing	butyrolactone hydrolase activity	Catalysis of the reaction: butyrolactone + H2O = 4-hydroxybutanoate.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0016									molecular_function											owl:Class	
GO:0008889	biolink:NamedThing	glycerophosphodiester phosphodiesterase activity	Catalysis of the reaction: a glycerophosphodiester + H2O = an alcohol + sn-glycerol 3-phosphate.	tmpzr1t_l9r_go_relaxed.owl	IgD-binding protein D|glycerophosphoryl diester phosphodiesterase activity|gene hpd protein|glycerophosphodiester glycerophosphohydrolase activity				MetaCyc:GLYCPDIESTER-RXN|RHEA:12969|Reactome:R-HSA-1483107|Reactome:R-HSA-1483116|EC:3.1.4.46									molecular_function											owl:Class	
GO:0102198	biolink:NamedThing	L-idonate 5-dehydrogenase activity (NAD-dependent)	Catalysis of the reaction: L-idonate + NAD = 5-dehydro-D-gluconate + NADH + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-12107|EC:1.1.1.366|RHEA:21172									molecular_function											owl:Class	
GO:1904858	biolink:NamedThing	negative regulation of endothelial cell chemotaxis to vascular endothelial growth factor	Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell chemotaxis to vascular endothelial growth factor.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of endothelial cell chemotaxis to vascular endothelial growth factor|downregulation of endothelial cell chemotaxis to vascular endothelial growth factor|down regulation of endothelial cell chemotaxis to vascular endothelial growth factor|inhibition of endothelial cell chemotaxis to vascular endothelial growth factor							rph	2015-12-16T11:47:52Z					biological_process											owl:Class	
GO:0036017	biolink:NamedThing	response to erythropoietin	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an erythropoietin stimulus. Erythropoietin is a glycoprotein hormone that controls erythropoiesis.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-10-12T10:11:04Z					biological_process											owl:Class	
GO:0019456	biolink:NamedThing	L-cysteine catabolic process via cystine, using cysteine transaminase	The chemical reactions and pathways resulting in the breakdown, via the compound cystine, of L-cysteine, catalyzed by the enzyme cysteine transaminase (EC:2.6.1.3).	tmpzr1t_l9r_go_relaxed.owl	L-cysteine breakdown via cystine, using cysteine transaminase|L-cysteine degradation via cystine, using cysteine transaminase													biological_process											owl:Class	
GO:0051379	biolink:NamedThing	epinephrine binding	Binding to epinephrine, a hormone produced by the medulla of the adrenal glands that increases heart activity, improves the power and prolongs the action of muscles, and increases the rate and depth of breathing. It is synthesized by the methylation of norepinephrine.	tmpzr1t_l9r_go_relaxed.owl	adrenaline binding													molecular_function											owl:Class	
GO:0045127	biolink:NamedThing	N-acetylglucosamine kinase activity	Catalysis of the reaction: N-acetyl-D-glucosamine + ATP = N-acetyl-D-glucosamine 6-phosphate + ADP + 2 H(+).	tmpzr1t_l9r_go_relaxed.owl	acetylaminodeoxyglucokinase activity|ATP:2-acetylamino-2-deoxy-D-glucose 6-phosphotransferase activity|2-acetylamino-2-deoxy-D-glucose kinase activity|acetylglucosamine kinase (phosphorylating)|ATP:N-acetyl-D-glucosamine 6-phosphotransferase activity|GlcNAc kinase activity				EC:2.7.1.59|MetaCyc:N-ACETYLGLUCOSAMINE-KINASE-RXN|KEGG_REACTION:R01201|Reactome:R-HSA-6803771|RHEA:17417									molecular_function											owl:Class	
GO:0015708	biolink:NamedThing	silicic acid import across plasma membrane	The directed movement of silicates from outside of a cell, across the plasma membrane and into the cytosol. Silicates are the salts of silicic acids, and are usually composed of silicon and oxygen (Si[x]O[y]), one or more metals, and possibly hydrogen. Types of silicate include unisilicates, metasilicates and hydrous silicates.	tmpzr1t_l9r_go_relaxed.owl	silicate transport|silicon uptake|silicic acid import|silicic acid transport							tb	2013-04-17T20:53:16Z			GO:1902067|GO:0051207		biological_process											owl:Class	
GO:0047460	biolink:NamedThing	L-2-amino-4-chloropent-4-enoate dehydrochlorinase activity	Catalysis of the reaction: L-2-amino-4-chloropent-4-enoate + H(2)O = 2-oxopent-4-enoate + chloride + H(+) + NH(4)(+).	tmpzr1t_l9r_go_relaxed.owl	L-2-amino-4-chloro-4-pentenoate dehalogenase activity|L-2-amino-4-chloropent-4-enoate chloride-lyase (adding H2O; deaminating; 2-oxopent-4-enoate-forming)|L-2-amino-4-chloropent-4-enoate chloride-lyase (deaminating)				KEGG_REACTION:R02605|EC:4.5.1.4|MetaCyc:4.5.1.4-RXN|RHEA:11620									molecular_function											owl:Class	
GO:0060490	biolink:NamedThing	lateral sprouting involved in lung morphogenesis	The process in which a branch forms along the side of the lung epithelial tube.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0101028	biolink:NamedThing	positive regulation of liquid surface tension	Any process that activates or increases the surface tension of a liquid.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of surface tension of a liquid													biological_process											owl:Class	
GO:0050828	biolink:NamedThing	regulation of liquid surface tension	Any process that modulates the surface tension of a liquid. Surface tension is the property that makes a liquid behave as if it had an elastic skin on its surface at the interface with a gas or an immiscible liquid.	tmpzr1t_l9r_go_relaxed.owl	regulation of surface tension of a liquid|surfactant activity													biological_process											owl:Class	
GO:0009643	biolink:NamedThing	photosynthetic acclimation	A response to light intensity in which exposure to medium-intensity light results in increased tolerance to high-intensity light.	tmpzr1t_l9r_go_relaxed.owl	photoacclimation|light acclimatization													biological_process											owl:Class	
GO:0102106	biolink:NamedThing	curcumin synthase activity	Catalysis of the reaction: feruloylacetyl-CoA + feruloyl-CoA(4-) + H2O <=> curcumin + 2 coenzyme A(4-) + carbon dioxide.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-11226|RHEA:34823|EC:2.3.1.217									molecular_function											owl:Class	
GO:0102812	biolink:NamedThing	4-coumaroyl-CoA:cyanidin-3-O-beta-D-glucoside-6''-O-acyltransferase activity	Catalysis of the reaction: 4-coumaryl-CoA + cyanidin 3-O-beta-D-glucoside betaine <=> cyanidin 3-(p-coumaroyl)-glucoside + coenzyme A.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-8204									molecular_function											owl:Class	
GO:1905748	biolink:NamedThing	hard palate morphogenesis	The developmental process by which a hard palate is generated and organized.	tmpzr1t_l9r_go_relaxed.owl	palatum durum morphogenesis							pga	2016-12-09T12:22:24Z					biological_process											owl:Class	
GO:0019273	biolink:NamedThing	L-alanine biosynthetic process via ornithine	The chemical reactions and pathways resulting in the formation of L-alanine, via the intermediate ornithine.	tmpzr1t_l9r_go_relaxed.owl	L-alanine anabolism via ornithine|L-alanine formation via ornithine|L-alanine synthesis via ornithine													biological_process											owl:Class	
GO:0102966	biolink:NamedThing	arachidoyl-CoA:1-dodecanol O-acyltransferase activity	Catalysis of the reaction: icosanoyl-CoA + dodecan-1-ol = arachidoyl dodecanoate + coenzyme A.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-9356|EC:2.3.1.75									molecular_function											owl:Class	
GO:0044392	biolink:NamedThing	peptidyl-lysine malonylation	The addition of a malonyl group (CO-CH2-CO) to peptidyl-lysine to form N6-malonyl-L-lysine.	tmpzr1t_l9r_go_relaxed.owl	lysine malonylation				RESID:AA0568			bf	2011-12-12T09:31:42Z					biological_process											owl:Class	
GO:0099137	biolink:NamedThing	altruistic, chimeric, non-reproductive fruiting body development	Development of a chimeric, non-reproductive fruiting body in which cells of all genotypes have an equal chance of becoming a spore cell.	tmpzr1t_l9r_go_relaxed.owl	fully co-operative, chimeric, non-reproductive fruiting body development													biological_process											owl:Class	
GO:0102013	biolink:NamedThing	ATPase-coupled L-glutamate tranmembrane transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + L-glutamate(out) -> ADP + phosphate + L-glutamate(in).	tmpzr1t_l9r_go_relaxed.owl	L-glutamate-importing ATPase activity				MetaCyc:ABC-13-RXN									molecular_function											owl:Class	
GO:0015426	biolink:NamedThing	ATPase-coupled polar amino acid-transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + polar amino acid(out) = ADP + phosphate + polar amino acid(in).	tmpzr1t_l9r_go_relaxed.owl	polar-amino acid ABC transporter|cystine/diaminopimelate porter activity|histidine permease activity|polar-amino-acid-transporting ATPase activity|polar-amino acid-transporting ATPase activity|polar-amino acid-importing ATPase activity|polar amino acid-importing ATPase activity|ATP-dependent polar amino acid-transporter activity|glutamate/aspartate porter activity|histidine/arginine/lysine/ornithine porter activity|polar amino acid uptake transporter activity				RHEA:14673|MetaCyc:3.6.3.21-RXN|EC:7.4.2.1									molecular_function											owl:Class	
GO:0030763	biolink:NamedThing	isobutyraldoxime O-methyltransferase activity	Catalysis of the reaction: 2-methylpropanal oxime + S-adenosyl-L-methionine = 2-methylpropanal O-methyloxime + S-adenosyl-L-homocysteine + H(+).	tmpzr1t_l9r_go_relaxed.owl	aldoxime methyltransferase activity|S-adenosyl-L-methionine:2-methylpropanal-oxime O-methyltransferase activity|aldoxime O-methyltransferase activity|S-adenosylmethionine:aldoxime O-methyltransferase activity				KEGG_REACTION:R04169|RHEA:10996|EC:2.1.1.91|MetaCyc:ISOBUTYRALDOXIME-O-METHYLTRANSFERASE-RXN									molecular_function											owl:Class	
GO:1902445	biolink:NamedThing	regulation of mitochondrial membrane permeability involved in programmed necrotic cell death	Any regulation of mitochondrial membrane permeability that is involved in programmed necrotic cell death.	tmpzr1t_l9r_go_relaxed.owl	regulation of transport across mitochondrial membrane involved in programmed necrotic cell death							dph	2013-10-11T13:11:20Z					biological_process											owl:Class	
GO:0005477	biolink:NamedThing	pyruvate secondary active transmembrane transporter activity	Enables the transfer of pyruvate from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters.	tmpzr1t_l9r_go_relaxed.owl	pyruvate carrier activity													molecular_function											owl:Class	
GO:0030586	biolink:NamedThing	[methionine synthase] reductase activity	Catalysis of the reaction: [methionine synthase]-cob(II)alamin + NADPH + H+ + S-adenosyl methionine = [methionine synthase]-methylcob(I)alamin + S-adenosylhomocysteine + NADP+.	tmpzr1t_l9r_go_relaxed.owl	5-methyltetrahydrofolate-homocysteine methyltransferase reductase|[methionine synthase]-cobalamin methyltransferase (cob(II)alamin reducing) activity|methionine synthase reductase activity|methionine synthase-methylcob(I)alamin,S-adenosylhomocysteine:NADP+ oxidoreductase activity|methionine synthase cob(II)alamin reductase (methylating) activity|methionine synthase-cobalamin methyltransferase (cob(II)alamin reducing)				Reactome:R-HSA-3149518|MetaCyc:2.1.1.135-RXN|EC:1.16.1.8|RHEA:23908	Formerly EC:2.1.1.135.								molecular_function											owl:Class	
GO:0034783	biolink:NamedThing	pivalate-CoA ligase activity	Catalysis of the reaction: pivalate + H+ + HSCoA + ATP = pivalyl-CoA + PPi + AMP.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r1032									molecular_function											owl:Class	
GO:0061463	biolink:NamedThing	O-acetyl-ADP-ribose deacetylase activity	Catalysis of the reaction O-acetyl-ADP-ribose + H2O = ADP-ribose + acetate.	tmpzr1t_l9r_go_relaxed.owl								dph	2012-10-05T11:05:06Z					molecular_function											owl:Class	
GO:0033734	biolink:NamedThing	(R)-benzylsuccinyl-CoA dehydrogenase activity	Catalysis of the reaction: (R)-2-benzylsuccinyl-CoA + 2 electron-transferring flavoprotein = (E)-2-benzylidenesuccinyl-CoA + 2 reduced electron-transferring flavoprotein.	tmpzr1t_l9r_go_relaxed.owl	BbsG|(R)-benzylsuccinyl-CoA:(acceptor) oxidoreductase activity|(R)-benzylsuccinyl-CoA:acceptor oxidoreductase activity				RHEA:20876|UM-BBD_reactionID:r0330|EC:1.3.8.3									molecular_function											owl:Class	
GO:0018861	biolink:NamedThing	4-chlorobenzoate-CoA ligase activity	Catalysis of the reaction: 4-chlorobenzoate + CoA + ATP = 4-chlorobenzoyl-CoA + AMP + diphosphate. This reaction requires magnesium and is part of the bacterial 2,4-dichlorobenzoate degradation pathway.	tmpzr1t_l9r_go_relaxed.owl	4-chlorobenzoate:CoA ligase activity				KEGG_REACTION:R03932|RHEA:23220|UM-BBD_reactionID:r0139|EC:6.2.1.33|MetaCyc:6.2.1.33-RXN									molecular_function											owl:Class	
GO:0102724	biolink:NamedThing	UDP-glucose:curcumin monoglucoside glucosyltransferase activity	Catalysis of the reaction: UDP-alpha-D-glucose + curcumin monoglucoside = H+ + curcumin diglucoside + UDP.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-7063									molecular_function											owl:Class	
GO:0035756	biolink:NamedThing	transepithelial migration of symbiont in host	The directional movement of an organism from one side of an epithelium to the other within its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	migration of symbiont within host by transepithelial trafficking|transmigration of symbiont in host|migration in host through an epithelial cell layer							bf	2011-03-24T10:20:03Z					biological_process											owl:Class	
GO:1904763	biolink:NamedThing	chaperone-mediated autophagy translocation complex assembly	The aggregation, arrangement and bonding together of a set of components to form a chaperone-mediated autophagy translocation complex.	tmpzr1t_l9r_go_relaxed.owl	CMA receptor complex formation|chaperone-mediated autophagy translocation complex formation|CMA receptor complex assembly|chaperone-mediated autophagy receptor complex assembly|CMA translocation complex formation|CMA translocation complex assembly|chaperone-mediated autophagy receptor complex formation							pad	2015-10-26T16:34:29Z					biological_process											owl:Class	
GO:0008854	biolink:NamedThing	exodeoxyribonuclease V activity	Catalysis of the exonucleolytic cleavage (in the presence of ATP) in either 5' to 3' or 3' to 5' direction to yield 5'-phosphooligonucleotides.	tmpzr1t_l9r_go_relaxed.owl	gene recBC endoenzyme|E. coli exonuclease V activity|exonuclease V activity|Escherichia coli exonuclease V|gene recBC DNase activity|E. coli exonuclease V|RecBC deoxyribonuclease activity|gene recBCD enzymes				EC:3.1.11.5|MetaCyc:3.1.11.5-RXN									molecular_function											owl:Class	
GO:0004656	biolink:NamedThing	procollagen-proline 4-dioxygenase activity	Catalysis of the reaction: procollagen L-proline + 2-oxoglutarate + O2 = procollagen trans-4-hydroxy-L-proline + succinate + CO2.	tmpzr1t_l9r_go_relaxed.owl	prolylprotocollagen dioxygenase activity|proline protocollagen hydroxylase activity|prolyl-glycyl-peptide, 2-oxoglutarate:oxygen oxidoreductase, 4-hydroxylating activity|collagen proline hydroxylase activity|peptidyl proline hydroxylase activity|protocollagen hydroxylase activity|protocollagen proline 4-hydroxylase activity|hydroxylase, collagen proline activity|proline, 2-oxoglutarate dioxygenase activity|prolyl 4-hydroxylase activity|protocollagen proline hydroxylase activity|prolyl hydroxylase activity|proline hydroxylase activity|prolylprotocollagen hydroxylase activity|procollagen-L-proline,2-oxoglutarate:oxygen oxidoreductase (4-hydroxylating) activity|procollagen-proline,2-oxoglutarate-4-dioxygenase activity|protocollagen proline dioxygenase activity|protocollagen prolyl hydroxylase activity|proline,2-oxoglutarate 4-dioxygenase activity				KEGG_REACTION:R03219|RHEA:18945|MetaCyc:1.14.11.2-RXN|EC:1.14.11.2|Reactome:R-HSA-1650808									molecular_function											owl:Class	
GO:0018114	biolink:NamedThing	threonine racemase activity	Catalysis of the reaction: L-threonine = D-threonine.	tmpzr1t_l9r_go_relaxed.owl					KEGG_REACTION:R01467|EC:5.1.1.6|MetaCyc:THREONINE-RACEMASE-RXN|RHEA:13913									molecular_function											owl:Class	
GO:0015763	biolink:NamedThing	N-acetylgalactosamine transport	The directed movement of N-acetylgalactosamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. N-acetylgalactosamine, 2-acetamido-2-deoxygalactopyranose, is the n-acetyl derivative of galactosamine.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0010541	biolink:NamedThing	acropetal auxin transport	The unidirectional movement of auxin from the base towards the apex of an organ, including the shoot, leaf, primary root, or lateral root.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0047869	biolink:NamedThing	dimethylpropiothetin dethiomethylase activity	Catalysis of the reaction: S,S-dimethyl-beta-propiothetin = acrylate + dimethyl sulfide + H(+).	tmpzr1t_l9r_go_relaxed.owl	desulfhydrase activity|S,S-dimethyl-beta-propiothetin dimethyl-sulfide-lyase activity|S,S-dimethyl-beta-propiothetin dimethyl-sulfide-lyase (acrylate-forming)				EC:4.4.1.3|RHEA:19965|MetaCyc:DIMETHYLPROPIOTHETIN-DETHIOMETHYLASE-RXN|KEGG_REACTION:R02574									molecular_function											owl:Class	
GO:0033926	biolink:NamedThing	glycopeptide alpha-N-acetylgalactosaminidase activity	Catalysis of the reaction: D-galactosyl-3-(N-acetyl-alpha-D-galactosaminyl)-L-serine + H2O = D-galactosyl-3-N-acetyl-alpha-D-galactosamine + L-serine in mucin-type glycoproteins.	tmpzr1t_l9r_go_relaxed.owl	endo-alpha-N-acetylgalactosaminidase activity|D-galactosyl-N-acetyl-alpha-D-galactosamine D-galactosyl-N-acetyl-galactosaminohydrolase activity|endo-alpha-acetylgalactosaminidase activity				EC:3.2.1.97|MetaCyc:3.2.1.97-RXN									molecular_function											owl:Class	
GO:1903212	biolink:NamedThing	protein localization to mating-type region heterochromatin	A process in which a protein is transported to, or maintained in, a location within a mating-type region heterochromatin.	tmpzr1t_l9r_go_relaxed.owl	protein localisation to mating-type region heterochromatin|protein localization in mating-type region heterochromatin|protein localisation in mating-type region heterochromatin							mah	2014-07-24T09:38:12Z					biological_process											owl:Class	
GO:0035613	biolink:NamedThing	RNA stem-loop binding	Binding to a stem-loop in an RNA molecule. An RNA stem-loop is a secondary RNA structure consisting of a double-stranded RNA (dsRNA) stem and a terminal loop.	tmpzr1t_l9r_go_relaxed.owl	RNA hairpin loop binding|RNA hairpin binding							bf	2010-11-26T10:41:49Z					molecular_function											owl:Class	
GO:0006896	biolink:NamedThing	Golgi to vacuole transport	The directed movement of substances from the Golgi to the vacuole.	tmpzr1t_l9r_go_relaxed.owl	Golgi to vacuole vesicle-mediated transport													biological_process											owl:Class	
GO:0050068	biolink:NamedThing	lysine carbamoyltransferase activity	Catalysis of the reaction: L-lysine + carbamoyl phosphate = L-homocitrulline + H(+) + phosphate.	tmpzr1t_l9r_go_relaxed.owl	carbamoyl-phosphate:L-lysine carbamoyltransferase activity|lysine transcarbamylase activity				MetaCyc:LYSINE-CARBAMOYLTRANSFERASE-RXN|EC:2.1.3.8|KEGG_REACTION:R01396|RHEA:17121									molecular_function											owl:Class	
GO:0038035	biolink:NamedThing	G protein-coupled receptor signaling in absence of ligand	A series of molecular signals beginning with a consequence of a G protein-coupled receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex, where the G protein-coupled receptor is not bound to an agonist.	tmpzr1t_l9r_go_relaxed.owl	G-protein coupled receptor signaling in absence of agonist|G-protein coupled receptor signalling in absence of ligand|basal G-protein coupled receptor signaling|G-protein coupled receptor signaling in absence of ligand					This term is intended for use by G protein-coupled receptors which signal at a low-level in the absence of agonist binding.		bf	2011-10-26T02:31:37Z					biological_process											owl:Class	
GO:0004957	biolink:NamedThing	prostaglandin E receptor activity	Combining with prostaglandin E (PGE(2)) to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	PGE(2) receptor activity|PGE receptor activity													molecular_function											owl:Class	
GO:0002417	biolink:NamedThing	B cell antigen processing and presentation mediated by B cell receptor uptake of antigen	B cell antigen processing and presentation which is initiated by uptake of antigen bound to the B cell receptor.	tmpzr1t_l9r_go_relaxed.owl	B-cell antigen processing and presentation mediated by B cell receptor uptake of antigen|B-lymphocyte antigen processing and presentation mediated by B cell receptor uptake of antigen|B lymphocyte antigen processing and presentation mediated by B cell receptor uptake of antigen													biological_process											owl:Class	
GO:0018404	biolink:NamedThing	protein-heparan sulfate linkage via heparan sulfate D-glucuronyl-D-galactosyl-D-galactosyl-D-xylosyl-L-serine	Heparan sulfate components are covalently linked to a core glycoprotein via O-glycosidic linkages between xylose and serine residues.	tmpzr1t_l9r_go_relaxed.owl	protein-heparan sulphate linkage via heparan sulphate D-glucuronyl-D-galactosyl-D-galactosyl-D-xylosyl-L-serine				RESID:AA0210									biological_process											owl:Class	
GO:0044103	biolink:NamedThing	L-arabinose 1-dehydrogenase (NADP+) activity	Catalysis of the reaction: L-arabinose + NADP+ = L-arabinono-1,4-lactone + NADPH + H+.	tmpzr1t_l9r_go_relaxed.owl					EC:1.1.1.376			jl	2009-07-09T04:00:30Z					molecular_function											owl:Class	
GO:0003844	biolink:NamedThing	1,4-alpha-glucan branching enzyme activity	Catalysis of the transfer of a segment of a (1->4)-alpha-D-glucan chain to a primary hydroxyl group in a similar glucan chain.	tmpzr1t_l9r_go_relaxed.owl	enzymatic branching factor|alpha-1,4-glucan:alpha-1,4-glucan-6-glycosyltransferase activity|starch branching enzyme|alpha-glucan-branching glycosyltransferase activity|branching enzyme activity|1,4-glucan-6-(1,4-glucano)-transferase activity|glucosan transglycosylase activity|plant branching enzyme|Q-enzyme|amylo-(1,4 to 1,6)transglucosidase activity|glycogen branching enzyme activity|branching glycosyltransferase activity|enzyme Q|1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-alpha-D-(1,4-alpha-D-glucano)-transferase activity|amylo-(1,4->1,6)-transglycosylase activity|amylose isomerase activity				MetaCyc:GLYCOGEN-BRANCH-RXN|Reactome:R-HSA-3322016|Reactome:R-HSA-3322005|Reactome:R-HSA-3322057|Reactome:R-HSA-3878762|EC:2.4.1.18									molecular_function											owl:Class	
GO:0033537	biolink:NamedThing	ajugose biosynthetic process using galactinol:raffinose galactosyltransferase	The chemical reactions and pathways resulting in the formation of ajugose, the hexasaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside, by a pathway in which galactinol:raffinose galactosyltransferase catalyzes chain elongation by transferring the alpha-galactosyl residue of galactinol to the oligosaccharide.	tmpzr1t_l9r_go_relaxed.owl	ajugose formation using galactinol:raffinose galactosyltransferase|ajugose biosynthesis using galactinol:raffinose galactosyltransferase|ajugose anabolism using galactinol:raffinose galactosyltransferase|ajugose synthesis using galactinol:raffinose galactosyltransferase				MetaCyc:PWY-5342									biological_process											owl:Class	
GO:0033536	biolink:NamedThing	ajugose biosynthetic process	The chemical reactions and pathways resulting in the formation of ajugose, the hexasaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside.	tmpzr1t_l9r_go_relaxed.owl	ajugose synthesis|ajugose biosynthesis|ajugose anabolism|ajugose formation													biological_process											owl:Class	
GO:0001179	biolink:NamedThing	RNA polymerase I general transcription initiation factor binding	Binding to an RNA polymerase I transcription factor, a protein required to initiate or regulate transcription by RNA polymerase I.	tmpzr1t_l9r_go_relaxed.owl	RNA polymerase I transcription factor binding							krc	2011-08-12T03:03:03Z					molecular_function											owl:Class	
GO:0047254	biolink:NamedThing	2,4-dihydroxy-7-methoxy-2H-1,4-benzoxazin-3(4H)-one 2-D-glucosyltransferase activity	Catalysis of the reaction: 2,4-dihydroxy-7-methoxy-2H-1,4-benzoxazin-3(4H)-one + UDP-D-glucose = 2,4-dihydroxy-7-methoxy-2H-1,4-benzoxazin-3(4H)-one 2-D-glucoside + UDP.	tmpzr1t_l9r_go_relaxed.owl	UDP-glucose:2,4-dihydroxy-7-methoxy-2H-1,4-benzoxazin-3(4H)-one 2-D-glucosyltransferase activity|UDPglucose:2,4-dihydroxy-7-methoxy-2H-1,4-benzoxazin-3(4H)-one 2-D-glucosyltransferase activity|uridine diphosphoglucose-2,4-dihydroxy-7-methoxy-2H-1,4-benzoxazin-3(4H)-one 2-glucosyltransferase activity				EC:2.4.1.202|RHEA:15541|MetaCyc:2.4.1.202-RXN									molecular_function											owl:Class	
GO:0010288	biolink:NamedThing	response to lead ion	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lead ion stimulus.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0047169	biolink:NamedThing	galactarate O-hydroxycinnamoyltransferase activity	Catalysis of the reaction: feruloyl-CoA + galactarate = 2-(E)-O-feruloyl-D-galactarate + CoA.	tmpzr1t_l9r_go_relaxed.owl	galacturate hydroxycinnamoyltransferase activity|feruloyl-CoA:galactarate O-(hydroxycinnamoyl)transferase activity				KEGG_REACTION:R03727|MetaCyc:2.3.1.130-RXN|EC:2.3.1.130|RHEA:12997									molecular_function											owl:Class	
GO:0060817	biolink:NamedThing	inactivation of paternal X chromosome	Compensating for the two-fold variation in X-chromosome:autosome ratios between sexes by a global inactivation of all, or most of, the genes specifically on the paternal X-chromosome in the XX sex.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-08-11T10:50:20Z					biological_process											owl:Class	
GO:0038106	biolink:NamedThing	choriogonadotropin hormone binding	Binding to choriogonadotropin hormone, a heterodimer, with an alpha subunit identical to that of luteinizing hormone (LH), follicle-stimulating hormone (FSH) and thyroid-stimulating hormone (TSH), and a unique beta subunit.	tmpzr1t_l9r_go_relaxed.owl	chorionic gonadotropin binding|chorionic gonadotrophin binding							bf	2012-03-08T03:58:40Z					molecular_function											owl:Class	
GO:0062074	biolink:NamedThing	pollen aperture	An area where exine is reduced or absent, in the pollen wall.	tmpzr1t_l9r_go_relaxed.owl								dph	2018-09-19T19:19:58Z					cellular_component											owl:Class	
GO:0061163	biolink:NamedThing	endoplasmic reticulum polarization	The endoplasmic reticulum organization process that results in the structure of the endoplasmic reticulum being oriented in the cell. Endoplasmic reticulum polarization serves as a mechanism to compartmentalize cellular activities and to establish cell polarity.	tmpzr1t_l9r_go_relaxed.owl	endoplasmic reticulum localization involved in endoplasmic reticulum polarization at cell division site|establishment of endoplasmic reticulum localisation involved in endoplasmic reticulum polarization at cell division site|ER polarization|endoplasmic reticulum localisation involved in endoplasmic reticulum polarization at cell division site|transitional endoplasmic reticulum polarization at cell division site|ER localization involved in ER polarization at cell division site|establishment of endoplasmic reticulum localization involved in endoplasmic reticulum polarization at cell division site|maintenance of endoplasmic reticulum location involved in endoplasmic reticulum polarization at cell division site	https://github.com/geneontology/go-ontology/issues/20666						dph	2010-06-25T09:51:48Z			GO:0061164|GO:0061167|GO:0061166|GO:0061165		biological_process											owl:Class	
GO:0032020	biolink:NamedThing	ISG15-protein conjugation	The covalent addition to a protein of ISG15, a ubiquitin-like protein.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0120124	biolink:NamedThing	membrane fusion priming complex	A protein complex that primes vacuolar or vesicular membranes for fusion with other intracellular membranes, by promoting the dissociation of cis-SNARE complexes.	tmpzr1t_l9r_go_relaxed.owl	LMA1 complex|GATE-16 complex							krc	2018-02-06T22:22:47Z					cellular_component											owl:Class	
GO:0000077	biolink:NamedThing	DNA damage checkpoint signaling	A signal transduction process that contributes to a DNA damage checkpoint.	tmpzr1t_l9r_go_relaxed.owl	DNA damage response, signal transduction resulting in cell cycle arrest|DNA damage checkpoint|signal transduction involved in DNA damage checkpoint				Wikipedia:DNA_damage_checkpoint|Wikipedia:Postreplication_checkpoint			mah	2010-12-08T04:18:11Z			GO:0072422		biological_process											owl:Class	
GO:0021960	biolink:NamedThing	anterior commissure morphogenesis	Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in one half of the cerebral cortex towards target cells in the contralateral half. This axonal process is a member of those that make up the anterior commissure, a small midline fiber tract that lies at the anterior end of the corpus callosum.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0000223	biolink:NamedThing	plasma membrane proton-transporting V-type ATPase, V1 domain	The V1 domain of a proton-transporting V-type ATPase found in the plasma membrane.	tmpzr1t_l9r_go_relaxed.owl	plasma membrane hydrogen ion-transporting ATPase V1 domain													cellular_component											owl:Class	
GO:0007358	biolink:NamedThing	establishment of central gap gene boundaries	Specification of the borders of central gap gene expression mediated largely by the effects of other gap genes; in insects this is exemplified by knirps repression of Kruppel.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0019696	biolink:NamedThing	toluene oxidation via toluene-cis-1,2-dihydrodiol	The degradation of toluene to form pyruvate and acetaldehyde; the first step in the pathway is the oxidation of toluene to form toluene-cis-1,2-dihydrodiol.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:TOLUENE-DEG-DIOL-PWY									biological_process											owl:Class	
GO:0035154	biolink:NamedThing	terminal cell fate specification, open tracheal system	The process in which a cell in an open tracheal system becomes capable of differentiating autonomously into a terminal cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed. Terminal cells send long and bifurcated hollow branches toward target tissues to allow oxygen exchange.	tmpzr1t_l9r_go_relaxed.owl	terminal cell fate specification													biological_process											owl:Class	
GO:0097173	biolink:NamedThing	N-acetylmuramic acid catabolic process	The chemical reactions and pathways resulting in the breakdown of N-acetylmuramic acid (MurNAc), a monosaccharide derivative of N-acetylglucosamine.	tmpzr1t_l9r_go_relaxed.owl	N-acetylmuramate catabolism|N-acetylmuramic acid breakdown|N-acetylmuramate catabolic process|N-acetylmuramate breakdown|N-acetylmuramate degradation|N-acetylmuramic acid degradation|N-acetylmuramic acid catabolism							pr	2011-10-07T12:48:47Z					biological_process											owl:Class	
GO:0002058	biolink:NamedThing	uracil binding	Binding to uracil.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0061516	biolink:NamedThing	monocyte proliferation	The expansion of a monocyte population by cell division.	tmpzr1t_l9r_go_relaxed.owl								dph	2013-04-18T13:14:24Z					biological_process											owl:Class	
GO:0071903	biolink:NamedThing	protein N-linked N-acetylglucosaminylation via asparagine	A process of protein N-linked glycosylation via asparagine in which N-acetylglucosamine is added to the N4 of asparagine, forming an (S)-2-amino-4-(2-acetamido-2-deoxy-beta-D-glucopyranosyl)amino-4-oxobutanoic acid residue.	tmpzr1t_l9r_go_relaxed.owl	protein amino acid N-linked N-acetylglucosaminylation via asparagine				RESID:AA0151			mah	2010-09-15T03:49:16Z					biological_process											owl:Class	
GO:0022882	biolink:NamedThing	protein-N(PI)-phosphohistidine-beta-glucoside phosphotransferase system transporter activity	Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + beta-glucoside(out) = protein histidine + beta-glucoside phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.	tmpzr1t_l9r_go_relaxed.owl	beta-glucoside PTS transporter activity													molecular_function											owl:Class	
GO:0008142	biolink:NamedThing	oxysterol binding	Binding to oxysterol, an oxidized form of cholesterol.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0061142	biolink:NamedThing	mesothelial-mesenchymal cell signaling involved in early lung development	Any process that mediates the transfer of information from a mesothelial cell to an epithelial cell and contributes to the development of the lung.	tmpzr1t_l9r_go_relaxed.owl	mesothelial-mesenchymal cell signalling involved in early lung development							dph	2010-05-25T09:35:32Z					biological_process											owl:Class	
GO:0046695	biolink:NamedThing	SLIK (SAGA-like) complex	A SAGA-type histone acetyltransferase complex that contains a smaller form of Spt7 (lacking the SPT8 binding region) than the fungal SAGA complex, and consequently lacks Spt8. The complex is involved in the yeast retrograde response pathway, which is important for gene expression changes during mitochondrial dysfunction.	tmpzr1t_l9r_go_relaxed.owl	SAGA (alt) complex|SALSA complex|SLIK/SALSA complex					See also the cellular component term 'SAGA complex ; GO:0000124'.								cellular_component											owl:Class	
GO:0070461	biolink:NamedThing	SAGA-type complex	A histone acetyltransferase complex that acetylates nucleosomal histones H2B, H3, or H4 and is required for the expression of a subset of Pol II-transcribed genes. This complex includes the acetyltransferases GCN5/KAT2A or PCAF/KAT2B, several proteins of the ADA, SGF and SPT families, and several TBP-associate proteins (TAFs).	tmpzr1t_l9r_go_relaxed.owl	SAGA family complex													cellular_component											owl:Class	
GO:0018257	biolink:NamedThing	peptidyl-lysine formylation	The modification of peptidyl-lysine to form peptidyl-N6-formyl-L-lysine.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0211									biological_process											owl:Class	
GO:0050883	biolink:NamedThing	musculoskeletal movement, spinal reflex action	Involuntary movement caused by the application of a stimulus to an organism and a subsequent movement. The signal processing of this movement takes place in the spinal cord.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1903728	biolink:NamedThing	luteal cell differentiation	The process in which a relatively unspecialized cell acquires the specialized features of a luteal cell. Large luteal cells develop from granulosa cells. Small luteal cells develop from theca cells.	tmpzr1t_l9r_go_relaxed.owl	lutein cell differentiation							cjm	2014-12-10T01:36:43Z					biological_process											owl:Class	
GO:0042601	biolink:NamedThing	endospore-forming forespore	Portion of the cell formed during the process of bacterial sporulation that will ultimately become the core of the endospore. An endospore is a type of dormant cell that is resistant to adverse conditions.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0010327	biolink:NamedThing	acetyl CoA:(Z)-3-hexen-1-ol acetyltransferase activity	Catalysis of the reaction: acetyl-CoA + (Z)-3-hexen-1-ol = CoA + (Z)-3-hexen-1-yl acetate.	tmpzr1t_l9r_go_relaxed.owl	hexenol acetyltransferase													molecular_function											owl:Class	
GO:0036298	biolink:NamedThing	recombinational interstrand cross-link repair	Removal of a DNA interstrand crosslink (a covalent attachment of DNA bases on opposite strands of the DNA) and restoration of the DNA by a mechanism that involves the exchange, reciprocal or nonreciprocal, of genetic material between the broken DNA molecule and a homologous DNA region.	tmpzr1t_l9r_go_relaxed.owl	recombination-dependent interstrand cross-link repair							bf	2012-08-07T11:11:59Z					biological_process											owl:Class	
GO:0036297	biolink:NamedThing	interstrand cross-link repair	Removal of a DNA interstrand crosslink (a covalent attachment of DNA bases on opposite strands of the DNA) and restoration of the DNA. DNA interstrand crosslinks occur when both strands of duplex DNA are covalently tethered together (e.g. by an exogenous or endogenous agent), thus preventing the strand unwinding necessary for essential DNA functions such as transcription and replication.	tmpzr1t_l9r_go_relaxed.owl	ICL repair							bf	2012-08-07T11:05:19Z					biological_process											owl:Class	
GO:0042901	biolink:NamedThing	arabinan transmembrane transporter activity	Enables the transfer of an arabinan, a polysaccharide composed of arabinose residues, from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0008066	biolink:NamedThing	glutamate receptor activity	Combining with glutamate and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0070912	biolink:NamedThing	Ddb1-Ckn1 complex	A heterodimeric nucleotide-excision repair complex that is involved in transcription-coupled repair. The subunits are known as Ddb1 and Ckn1 in S. pombe; Ddb1 contains a motif called the DDB-box that interacts with adaptor proteins for DDB1/cullin 4 ubiquitin ligases.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-09-09T03:41:04Z					cellular_component											owl:Class	
GO:0047295	biolink:NamedThing	geranylgeranylglycerol-phosphate geranylgeranyltransferase activity	Catalysis of the reaction: sn-3-O-(geranylgeranyl)glycerol 1-phosphate + all-trans-geranylgeranyl diphosphate = 2,3-di-O-(geranylgeranyl)glycerol 1-phosphate + diphosphate.	tmpzr1t_l9r_go_relaxed.owl	geranylgeranyloxyglycerol phosphate geranylgeranyltransferase activity|geranylgeranyltransferase II|geranylgeranyl diphosphate:sn-3-O-(geranylgeranyl)glycerol 1-phosphate geranylgeranyltransferase activity				EC:2.5.1.42|MetaCyc:2.5.1.42-RXN|KEGG_REACTION:R04520|RHEA:18109									molecular_function											owl:Class	
GO:0033413	biolink:NamedThing	UGU codon-amino acid adaptor activity	A triplet codon-amino acid adaptor activity that recognizes a UGU codon.	tmpzr1t_l9r_go_relaxed.owl	TGT codon-amino acid adaptor activity|cysteine tRNA					Note that in the standard genetic code, TGT codes for cysteine.								molecular_function											owl:Class	
GO:0060208	biolink:NamedThing	proestrus	The estrous cycle phase in which there is heightened follicular activity.	tmpzr1t_l9r_go_relaxed.owl						Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase. To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).								biological_process											owl:Class	
GO:0050384	biolink:NamedThing	urate-ribonucleotide phosphorylase activity	Catalysis of the reaction: 3-(beta-D-ribofuranosyl)uric acid + phosphate = alpha-D-ribose 1-phosphate + H(+) + urate.	tmpzr1t_l9r_go_relaxed.owl	urate-ribonucleotide:phosphate alpha-D-ribosyltransferase activity|urate-ribonucleotide:phosphate D-ribosyltransferase activity|UAR phosphorylase activity				RHEA:13909|KEGG_REACTION:R02646|MetaCyc:URATE-RIBONUCLEOTIDE-PHOSPHORYLASE-RXN|EC:2.4.2.16									molecular_function											owl:Class	
GO:0042768	biolink:NamedThing	ecdysteroid 2-hydroxylase activity	Catalysis of the hydroxylation of an ecdysteroid at carbon position 2.	tmpzr1t_l9r_go_relaxed.owl						Note that in the ecdysteroidogenic pathway, this activity catalyzes the conversion of 2-deoxyecdysone to ecdysone. It can also catalyze the conversion of 2,22-dideoxyecdysone (ketotriol) to 22-deoxyecdysone.								molecular_function											owl:Class	
GO:0099622	biolink:NamedThing	cardiac muscle cell membrane repolarization	The process in which ions are transported across the plasma membrane of a cardiac muscle cell such that the membrane potential changes in the repolarizing direction, toward the steady state potential. For example, the repolarization during an action potential is from a positive membrane potential towards a negative resting potential.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0055087	biolink:NamedThing	Ski complex	A protein complex that regulates RNA degradation by the exosome complex. In Saccharomyces the complex has a heterotetrameric stoichiometry consisting of one copy each of Ski2p and Ski3 and two copies of Ski8p.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Ski_complex									cellular_component											owl:Class	
GO:0061201	biolink:NamedThing	clathrin-sculpted gamma-aminobutyric acid transport vesicle lumen	The volume enclosed by the membrane of the clathrin-sculpted gamma-aminobutyric acid transport vesicle.	tmpzr1t_l9r_go_relaxed.owl	clathrin sculpted GABA transport vesicle lumen|clathrin sculpted gamma-aminobutyric acid transport vesicle lumen							dph	2010-07-29T10:45:05Z					cellular_component											owl:Class	
GO:0033608	biolink:NamedThing	formyl-CoA transferase activity	Catalysis of the reaction: formyl-CoA + oxalate = formate + oxalyl-CoA.	tmpzr1t_l9r_go_relaxed.owl	formyl-CoA:oxalate CoA-transferase activity|formyl-coenzyme A transferase activity|formyl-CoA oxalate CoA-transferase activity				MetaCyc:RXN0-1382|EC:2.8.3.16|KEGG_REACTION:R07290|RHEA:16545									molecular_function											owl:Class	
GO:0047365	biolink:NamedThing	quercetin-3-sulfate 3'-sulfotransferase activity	Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + quercetin 3-sulfate = adenosine 3',5'-diphosphate + H(+) + quercetin 3,3'-disulfate.	tmpzr1t_l9r_go_relaxed.owl	flavonol 3'-sulfotransferase activity|quercetin-3-sulphate 3'-sulphotransferase activity|3'-phosphoadenylyl-sulfate:quercetin-3-sulfate 3'-sulfotransferase activity|PAPS:flavonol 3-sulfate 3'-sulfotransferase activity|3'-sulfotransferase activity				KEGG_REACTION:R02632|EC:2.8.2.26|RHEA:22504|MetaCyc:2.8.2.26-RXN									molecular_function											owl:Class	
GO:1902783	biolink:NamedThing	cellular response to decane	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a decane stimulus.	tmpzr1t_l9r_go_relaxed.owl								tt	2014-03-21T12:50:14Z					biological_process											owl:Class	
GO:0047104	biolink:NamedThing	hexadecanal dehydrogenase (acylating) activity	Catalysis of the reaction: CoA + NAD(+) + palmitaldehyde = H(+) + NADH + palmitoyl-CoA.	tmpzr1t_l9r_go_relaxed.owl	fatty acyl-CoA reductase activity|hexadecanal:NAD+ oxidoreductase (CoA-acylating)				MetaCyc:1.2.1.42-RXN|UM-BBD_reactionID:r1374|KEGG_REACTION:R01277|RHEA:19705|EC:1.2.1.42									molecular_function											owl:Class	
GO:0038139	biolink:NamedThing	ERBB4-EGFR complex	A heterodimeric complex between the tyrosine kinase receptors ERBB4 (also called HER4) and epidermal growth factor receptor (EGFR/ERBB1).	tmpzr1t_l9r_go_relaxed.owl	ERBB4:EGFR heterodimer|EGFR-ERBB4 complex							bf	2012-03-30T01:59:41Z					cellular_component											owl:Class	
GO:0002945	biolink:NamedThing	cyclin K-CDK13 complex	A protein complex consisting of cyclin Kand cyclin-dependent kinase 13 (CDK13). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner.	tmpzr1t_l9r_go_relaxed.owl	CycK/Cdk13 complex							hjd	2012-12-05T16:13:28Z					cellular_component											owl:Class	
GO:0140685	biolink:NamedThing	histone H3-di/monomethyl-lysine-9 FAD-dependent demethylase activity	Catalysis of the removal of a methyl group from a di- or a monomethyl-lysine residue at position 9 of the histone H3 protein. This is a flavin adenine dinucleotide (FAD)-dependent amine oxidation reaction.	tmpzr1t_l9r_go_relaxed.owl	histone H3K9me demethylase activity|histone H3K9me2 demethylase activity	https://github.com/geneontology/go-ontology/issues/21089						pg	2021-07-09T07:18:00Z					molecular_function											owl:Class	
GO:0009906	biolink:NamedThing	response to photoperiod, blue light	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the detection of a blue light photoperiod stimulus. Blue light is electromagnetic radiation with a wavelength of between 440 and 500nm.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0045486	biolink:NamedThing	naringenin 3-dioxygenase activity	Catalysis of the reaction: naringenin + 2-oxoglutarate + O2 = dihydrokaempferol + succinate + CO2.	tmpzr1t_l9r_go_relaxed.owl	flavanone 3beta-hydroxylase activity|(2S)-flavanone 3-hydroxylase activity|flavanone 3-beta-hydroxylase activity|flavanone 3-dioxygenase activity|flavanone 3-hydroxylase activity|naringenin 3-hydroxylase activity|flavanone,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating)|naringenin,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating) activity|flavanone synthase I activity				MetaCyc:NARINGENIN-3-DIOXYGENASE-RXN|EC:1.14.11.9|RHEA:18621									molecular_function											owl:Class	
GO:0043965	biolink:NamedThing	suppression by symbiont of host adenylate cyclase-mediated signal transduction	Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of adenylate cyclase-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	negative regulation by symbiont of host adenylate cyclase-mediated signal transduction													biological_process											owl:Class	
GO:0019137	biolink:NamedThing	thioglucosidase activity	Catalysis of the reaction: a thioglucoside + H2O = a thiol + a sugar.	tmpzr1t_l9r_go_relaxed.owl	myrosinase activity|sinigrase activity|thioglucoside glucohydrolase activity|sinigrinase activity				MetaCyc:RXN-9946|EC:3.2.1.147									molecular_function											owl:Class	
GO:0000908	biolink:NamedThing	taurine dioxygenase activity	Catalysis of the reaction: 2-oxoglutarate + O(2) + taurine = aminoacetaldehyde + CO(2) + succinate + sulfite.	tmpzr1t_l9r_go_relaxed.owl	2-aminoethanesulfonate dioxygenase activity|alpha-ketoglutarate-dependent taurine dioxygenase activity|taurine, 2-oxoglutarate:O2 oxidoreductase (sulfite-forming)				RHEA:15909|EC:1.14.11.17|MetaCyc:RXN0-299|KEGG_REACTION:R05320									molecular_function											owl:Class	
GO:0097620	biolink:NamedThing	(R)-mandelate dehydrogenase activity	Catalysis of the reaction: (R)-2-hydroxy-2-phenylacetate + acceptor = phenylglyoxylate + reduced acceptor.	tmpzr1t_l9r_go_relaxed.owl	D-mandelate dehydrogenase activity				RHEA:43112	In the yeast Rhodotorula graminis, (R)-mandelate dehydrogenase is the first enzyme of the mandelate pathway, and catalyzes the NAD-dependent oxidation of (R)-mandelate to phenylglyoxylate.		pr	2014-07-30T09:53:23Z					molecular_function											owl:Class	
GO:0003259	biolink:NamedThing	cardioblast anterior-lateral migration	The orderly movement of a cardioblast toward the head and laterally to form the heart field. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-10-15T01:17:28Z					biological_process											owl:Class	
GO:0003260	biolink:NamedThing	cardioblast migration	The orderly movement of a cardiac progenitor cell to form the heart field. Cardiac progenitor cells are non-terminally differentiated, mesoderm-derived cells that are committed to differentiate into cells of the heart. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-10-15T01:52:25Z					biological_process											owl:Class	
GO:0140384	biolink:NamedThing	metacyclogenesis	The morphological, biochemical and genetic changes that induce the differentiation of non-pathogenic parasites into pathogenic metacyclic parasites in the Trypanosomatidae species. The pathogenic parasites are known as metacyclic trypomastigotes in Trypanosoma and metacyclic promastigotes in Leishmania.	tmpzr1t_l9r_go_relaxed.owl								pg	2019-11-20T13:25:55Z					biological_process											owl:Class	
GO:0052775	biolink:NamedThing	endo-1,3-alpha-L-rhamnosidase activity	Catalysis of the reaction: R1-L-rhamnose-(1->3)-alpha-L-rhamnose-R2 + H2O = R1-L-rhamnose + L-rhamnose-R2. This reaction is the hydrolysis of an alpha-(1->3) linkage between two rhamnose residues in a polysaccharide chain.	tmpzr1t_l9r_go_relaxed.owl	endo-(1,3)-alpha-L-rhamnosidase activity|endorhamnosidase activity|endo-(1->3)-alpha-L-rhamnosidase activity							ai	2011-10-05T03:30:33Z					molecular_function											owl:Class	
GO:0004639	biolink:NamedThing	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity	Catalysis of the reaction: 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + L-aspartate + ATP = (2S)-2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate + ADP + 2 H(+) + phosphate.	tmpzr1t_l9r_go_relaxed.owl	phosphoribosylaminoimidazolesuccinocarboxamide synthetase activity|phosphoribosylaminoimidazole-succinocarboxamide synthase activity|SAICARs activity|phosphoribosylaminoimidazole-succinocarboxamide synthetase activity|4-[(N-succinylamino)carbonyl]-5-aminoimidazole ribonucleotide synthetase activity|4-(N-succinocarboxamide)-5-aminoimidazole synthetase activity|PurC|SAICAR synthase activity|4-((N-succinylamino)carbonyl)-5-aminoimidazole ribonucleotide synthetase activity|5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate:L-aspartate ligase (ADP-forming)|SAICAR synthetase activity|5-aminoimidazole-4-N-succinocarboxamide ribonucleotide synthetase activity				Reactome:R-HSA-73805|RHEA:22628|MetaCyc:SAICARSYN-RXN|KEGG_REACTION:R04591|EC:6.3.2.6									molecular_function											owl:Class	
GO:0018238	biolink:NamedThing	peptidyl-lysine carboxyethylation	The modification of peptidyl-lysine to form peptidyl-N6-1-carboxyethyl-L-lysine.	tmpzr1t_l9r_go_relaxed.owl	protein amino acid carboxyethylation				RESID:AA0115							GO:0018239		biological_process											owl:Class	
GO:0071945	biolink:NamedThing	regulation of bacterial-type flagellum-dependent cell motility by regulation of motor speed	A process that modulates flagellum-dependent motility in bacteria by modulating the speed or direction of rotation of a rotary flagellar motor, mediated by interactions between the braking protein.	tmpzr1t_l9r_go_relaxed.owl	regulation of bacterial-type flagellum cell motility by regulation of motor speed|regulation of flagellar cell motility by regulation of motor speed|regulation of bacterial-type flagellar cell motility by regulation of motor speed							mah	2010-10-05T04:10:27Z					biological_process											owl:Class	
GO:0019194	biolink:NamedThing	sorbose transmembrane transporter activity	Enables the transfer of sorbose from one side of a membrane to the other. Sorbose is the ketohexose xylo-2-hexulose; L-sorbose is formed by bacterial oxidation of sorbitol. Sorbose is produced commercially by fermentation and is used as an intermediate in the manufacture of ascorbic acid.	tmpzr1t_l9r_go_relaxed.owl	sorbose porter activity											GO:0019193		molecular_function											owl:Class	
GO:0050217	biolink:NamedThing	propioin synthase activity	Catalysis of the reaction: 4-hydroxyhexan-3-one = 2 propanal.	tmpzr1t_l9r_go_relaxed.owl	4-hydroxy-3-hexanone propanal-lyase activity|4-hydroxy-3-hexanone aldolase activity|4-hydroxy-3-hexanone propanal-lyase (propanal-forming)				MetaCyc:PROPIOIN-SYNTHASE-RXN|KEGG_REACTION:R00038|EC:4.1.2.35|RHEA:11100									molecular_function											owl:Class	
GO:0021975	biolink:NamedThing	pons reticulospinal tract morphogenesis	Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the pons towards target cells in the spinal cord.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0090471	biolink:NamedThing	9,15,9'-tri-cis-zeta-carotene isomerase activity	Catalysis of the reaction: 9,15,9'-tricis-zeta-carotene = 9,9'-dicis-zeta-carotene.	tmpzr1t_l9r_go_relaxed.owl	9,15,9'-tricis-zeta-carotene cis-trans-isomerase							tb	2012-09-24T16:29:49Z					molecular_function											owl:Class	
GO:0061470	biolink:NamedThing	T follicular helper cell differentiation	The process in which a relatively unspecialized T cell acquires specialized features of a mature T follicular helper cell.	tmpzr1t_l9r_go_relaxed.owl	T-helper follicular cell differentiation							dph	2012-11-02T09:01:48Z					biological_process											owl:Class	
GO:0033513	biolink:NamedThing	L-lysine catabolic process to acetyl-CoA via 5-aminopentanamide	The chemical reactions and pathways resulting in the breakdown of L-lysine into other compounds, including acetyl-CoA, via the intermediate 5-aminopentanamide.	tmpzr1t_l9r_go_relaxed.owl	L-lysine breakdown to acetyl-CoA via 5-aminopentanamide|L-lysine degradation to acetyl-CoA via 5-aminopentanamide				MetaCyc:PWY-5280									biological_process											owl:Class	
GO:0061384	biolink:NamedThing	heart trabecula morphogenesis	The process of shaping a trabecula in the heart. A trabecula is a small, often microscopic, tissue element in the form of a small beam, strut or rod, which generally has a mechanical function. Trabecula are usually but not necessarily, composed of dense collagenous tissue.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-12-02T08:54:20Z					biological_process											owl:Class	
GO:0030833	biolink:NamedThing	regulation of actin filament polymerization	Any process that modulates the frequency, rate or extent of the assembly of actin filaments by the addition of actin monomers to a filament.	tmpzr1t_l9r_go_relaxed.owl	regulation of actin polymerization													biological_process											owl:Class	
GO:1990142	biolink:NamedThing	envenomation resulting in hemolysis in other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with hemolysis in the bitten organism.	tmpzr1t_l9r_go_relaxed.owl								sp	2013-07-18T10:46:03Z					biological_process											owl:Class	
GO:0044649	biolink:NamedThing	envenomation resulting in cytolysis in other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with cytolysis in the bitten organism.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-07-11T02:13:38Z					biological_process											owl:Class	
GO:0061759	biolink:NamedThing	alpha-ketoglutarate reductase activity	Catalysis of the reaction: 2-oxoglutarate + reduced acceptor = (S)-2-hydroxyglutarate + acceptor.	tmpzr1t_l9r_go_relaxed.owl	2-oxoglutarate reductase activity|2-hydroxyglutarate dehydrogenase activity, reverse reaction|2-ketoglutarate reductase activity|D-2HG reductase activity				RHEA:21254			dph	2016-03-07T08:38:57Z					molecular_function											owl:Class	
GO:1904929	biolink:NamedThing	coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway	Any coreceptor activity that is involved in Wnt signaling pathway, planar cell polarity pathway.	tmpzr1t_l9r_go_relaxed.owl	Wnt co-receptor activity, non-canonical signaling|coreceptor activity involved in Wnt receptor signaling pathway, planar cell polarity pathway|coreceptor, soluble ligand activity involved in Wnt signaling pathway, planar cell polarity pathway|coreceptor, insoluble ligand activity involved in Wnt-JNK signaling pathway|coreceptor, insoluble ligand activity involved in Wnt receptor signaling pathway, planar cell polarity pathway|coreceptor activity involved in Wnt-PCP signaling pathway|coreceptor, insoluble ligand activity involved in planar cell polarity pathway|coreceptor, soluble ligand activity involved in planar cell polarity pathway|coreceptor, soluble ligand activity involved in PCP pathway|coreceptor, insoluble ligand activity involved in Wnt-activated signaling pathway, planar cell polarity pathway|coreceptor, insoluble ligand activity involved in Wnt receptor signalling pathway, planar cell polarity pathway|coreceptor, soluble ligand activity involved in non-canonical Wnt signaling pathway|coreceptor activity involved in Wnt-JNK signaling pathway|coreceptor, soluble ligand activity involved in Wnt-PCP signaling pathway|coreceptor, soluble ligand activity involved in Wnt-activated signaling pathway, planar cell polarity pathway|coreceptor, insoluble ligand activity involved in non-canonical Wnt signaling pathway|coreceptor activity involved in non-canonical Wnt signaling pathway|Wnt/PCP co-receptor activity|coreceptor, soluble ligand activity involved in Wnt receptor signaling pathway, planar cell polarity pathway|coreceptor activity involved in Wnt-activated signaling pathway, planar cell polarity pathway|coreceptor activity involved in PCP pathway|coreceptor, insoluble ligand activity involved in Wnt-PCP signaling pathway|coreceptor, soluble ligand activity involved in Wnt receptor signalling pathway, planar cell polarity pathway|coreceptor activity involved in Wnt receptor signalling pathway, planar cell polarity pathway|coreceptor, insoluble ligand activity involved in PCP pathway|coreceptor, insoluble ligand activity involved in Wnt signaling pathway, planar cell polarity pathway|coreceptor activity involved in planar cell polarity pathway|coreceptor, soluble ligand activity involved in Wnt-JNK signaling pathway|Wnt co-receptor, non-canonical pathway							bf	2016-01-28T15:15:01Z					molecular_function											owl:Class	
GO:0002656	biolink:NamedThing	negative regulation of tolerance induction to nonself antigen	Any process that stops, prevents, or reduces the frequency, rate, or extent of tolerance induction to nonself antigen.	tmpzr1t_l9r_go_relaxed.owl	down regulation of tolerance induction to nonself antigen|inhibition of tolerance induction to nonself antigen|downregulation of tolerance induction to nonself antigen|down-regulation of tolerance induction to nonself antigen													biological_process											owl:Class	
GO:0018123	biolink:NamedThing	peptidyl-cysteine ADP-ribosylation	The transfer, from NAD, of ADP-ribose to peptidyl-cysteine to form peptidyl-S-(ADP-ribosyl)-L-cysteine.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0169									biological_process											owl:Class	
GO:0045902	biolink:NamedThing	negative regulation of translational fidelity	Any process that decreases the ability of the translational apparatus to interpret the genetic code.	tmpzr1t_l9r_go_relaxed.owl	down regulation of translational fidelity|downregulation of translational fidelity|down-regulation of translational fidelity|inhibition of translational fidelity													biological_process											owl:Class	
GO:0047522	biolink:NamedThing	15-oxoprostaglandin 13-oxidase activity	Catalysis of the reaction: (5Z)-(15S)-11-alpha-hydroxy-9,15-dioxoprostanoate + NAD(P)+ -> (5Z)-(15S)-11-alpha-hydroxy-9,15-dioxoprosta-13-enoate + NAD(P)H + H+.	tmpzr1t_l9r_go_relaxed.owl	(5Z)-(15S)-11alpha-hydroxy-9,15-dioxoprostanoate:NAD(P)+ delta13-oxidoreductase activity				KEGG_REACTION:R04557|MetaCyc:15-OXOPROSTAGLANDIN-13-REDUCTASE-RXN|EC:1.3.1.48|KEGG_REACTION:R04556	Note that this is the reverse of the reaction described in '13-prostaglandin reductase activity ; GO:0036132'.								molecular_function											owl:Class	
GO:0036331	biolink:NamedThing	avascular cornea development in camera-type eye	The progression of an avascular cornea over time, from its formation to the mature structure. Corneal avascularity (the absence of blood vessels in the cornea) is required for optical clarity and optimal vision. Avascular corneas are present in most animals, except Manatees.	tmpzr1t_l9r_go_relaxed.owl	avascular cornea development							bf	2012-09-05T09:07:14Z					biological_process											owl:Class	
GO:0071290	biolink:NamedThing	cellular response to platinum ion	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a platinum stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to platinum							mah	2009-12-10T04:08:06Z					biological_process											owl:Class	
GO:0047714	biolink:NamedThing	galactolipase activity	Catalysis of the reaction: 1,2-diacyl-3-beta-D-galactosyl-sn-glycerol + 2 H2O = 3-beta-D-galactosyl-sn-glycerol + 2 carboxylates.	tmpzr1t_l9r_go_relaxed.owl	galactolipid acylhydrolase activity|1,2-diacyl-3-beta-D-galactosyl-sn-glycerol acylhydrolase activity|galactolipid lipase activity|polygalactolipase activity				RHEA:13189|MetaCyc:GALACTOLIPASE-RXN|EC:3.1.1.26									molecular_function											owl:Class	
GO:0071757	biolink:NamedThing	hexameric IgM immunoglobulin complex	A circulating form of IgM consisting of a hexamer of IgM core units with a single J chain polypeptide.	tmpzr1t_l9r_go_relaxed.owl	hexameric IgM antibody					Note that an IgM immunoglobulin complex has the function of antigen binding if a suitable antigen is available.		mah	2010-03-24T01:44:53Z					cellular_component											owl:Class	
GO:0071952	biolink:NamedThing	conversion of O-phosphoseryl-tRNA to cysteinyl-tRNA	The modification process that results in the conversion of O-phosphoserine charged on a tRNA(Cys) to cysteinyl-tRNA.	tmpzr1t_l9r_go_relaxed.owl						Note that this process has been observed in some archaeal and bacterial species.		mah	2010-10-08T12:02:00Z					biological_process											owl:Class	
GO:0031815	biolink:NamedThing	P2Y5 nucleotide receptor binding	Binding to a P2Y5 nucleotide receptor.	tmpzr1t_l9r_go_relaxed.owl	P2Y5 nucleotide receptor ligand													molecular_function											owl:Class	
GO:1905190	biolink:NamedThing	negative regulation of metaphase/anaphase transition of meiosis II	Any process that stops, prevents or reduces the frequency, rate or extent of metaphase/anaphase transition of meiosis II.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of meiosis II metaphase/anaphase transition							vw	2016-05-10T16:46:57Z					biological_process											owl:Class	
GO:2000436	biolink:NamedThing	positive regulation of protein neddylation	Any process that activates or increases the frequency, rate or extent of protein neddylation.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of RUB1-protein conjugation							vw	2011-03-03T02:06:19Z					biological_process											owl:Class	
GO:0102726	biolink:NamedThing	DIMBOA glucoside beta-D-glucosidase activity	Catalysis of the reaction: (2R)-DIMBOA glucoside + H2O = H+ + DIMBOA + beta-D-glucose.	tmpzr1t_l9r_go_relaxed.owl					RHEA:33975|MetaCyc:RXN-7082|EC:3.2.1.182									molecular_function											owl:Class	
GO:0044074	biolink:NamedThing	negative regulation by symbiont of host translation	The process in which a symbiont organism stops, prevents, or reduces the frequency, rate or extent of translation, the chemical reactions and pathways resulting in the formation of a protein, in its host organism.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of host translation by symbiont													biological_process											owl:Class	
GO:0120170	biolink:NamedThing	intraciliary transport particle B binding	Binding to an intraciliary transport particle B (IFT B) complex.	tmpzr1t_l9r_go_relaxed.owl	IFT B complex binding|intraciliary transport complex B binding|intraflagellar transport complex B binding|intraflagellar transport particle B binding							krc	2018-05-11T22:28:11Z					molecular_function											owl:Class	
GO:0060559	biolink:NamedThing	positive regulation of calcidiol 1-monooxygenase activity	Any process that increases the rate, frequency or extent of calcidiol 1-monooxygenase activity. Calcidiol 1-monooxygenase activity is the catalysis of the reaction: calcidiol + NADPH + H+ + O2 = calcitriol + NADP+ + H2O.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-04-13T02:57:28Z					biological_process											owl:Class	
GO:0047923	biolink:NamedThing	gentisate decarboxylase activity	Catalysis of the reaction: 2,5-dihydroxybenzoate + H(+) = CO(2) + hydroquinone.	tmpzr1t_l9r_go_relaxed.owl	2,5-dihydroxybenzoate decarboxylase activity|gentisate carboxy-lyase activity|2,5-dihydroxybenzoate carboxy-lyase (hydroquinone-forming)				KEGG_REACTION:R02489|RHEA:21312|EC:4.1.1.62|MetaCyc:GENTISATE-DECARBOXYLASE-RXN									molecular_function											owl:Class	
GO:1903241	biolink:NamedThing	U2-type prespliceosome assembly	The aggregation, arrangement and bonding together of a set of components to form an U2-type prespliceosome.	tmpzr1t_l9r_go_relaxed.owl	major prespliceosome assembly|yeast U2-type spliceosomal complex B assembly|GT-AG prespliceosome formation|mammalian U2-type spliceosomal complex A formation|U2-type prespliceosome formation|mammalian U2-type spliceosomal complex A assembly|GT-AG prespliceosome assembly|yeast U2-type spliceosomal complex B formation|major prespliceosome formation							mah	2014-08-01T14:33:45Z					biological_process											owl:Class	
GO:0047939	biolink:NamedThing	L-glucuronate reductase activity	Catalysis of the reaction: L-gulonate + NADP(+) = D-glucuronate + H(+) + NADPH.	tmpzr1t_l9r_go_relaxed.owl	glucuronate reductase activity|D-glucuronate reductase activity|D-glucuronate dehydrogenase activity|NADP-L-gulonate dehydrogenase activity|TPN-L-gulonate dehydrogenase activity|glucuronate dehydrogenase activity|aldehyde reductase II activity				KEGG_REACTION:R01481|Reactome:R-HSA-5661256|EC:1.1.1.19|MetaCyc:GLUCURONATE-REDUCTASE-RXN|RHEA:14909									molecular_function											owl:Class	
GO:0008689	biolink:NamedThing	3-demethylubiquinone-9 3-O-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + 3-demethylubiquinone-9 = S-adenosyl-L-homocysteine + ubiquinone-9.	tmpzr1t_l9r_go_relaxed.owl	OMHMB-methyltransferase activity|S-adenosyl-L-methionine:2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinone 3-O-methyltransferase activity|5-demethylubiquinone-9 methyltransferase activity|S-adenosyl-L-methionine:2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinone-O-methyltransferase activity				EC:2.1.1.64|RHEA:17049|MetaCyc:DHHB-METHYLTRANSFER-RXN									molecular_function											owl:Class	
GO:2000347	biolink:NamedThing	positive regulation of hepatocyte proliferation	Any process that activates or increases the frequency, rate or extent of hepatocyte proliferation.	tmpzr1t_l9r_go_relaxed.owl								mah	2011-02-03T10:27:24Z					biological_process											owl:Class	
GO:0008675	biolink:NamedThing	2-dehydro-3-deoxy-phosphogluconate aldolase activity	Catalysis of the reaction: 2-dehydro-3-deoxy-D-gluconate 6-phosphate = pyruvate + D-glyceraldehyde 3-phosphate.	tmpzr1t_l9r_go_relaxed.owl	2-keto-3-deoxy-6-phosphogluconic aldolase activity|6-phospho-2-keto-3-deoxygluconate aldolase activity|2-dehydro-3-deoxy-D-gluconate-6-phosphate D-glyceraldehyde-3-phosphate-lyase activity|2-dehydro-3-deoxy-D-gluconate-6-phosphate D-glyceraldehyde-3-phosphate-lyase (pyruvate-forming)|phospho-2-keto-3-deoxygluconate aldolase activity|2-keto-3-deoxygluconate-6-phosphate aldolase activity|KDPG-aldolase activity|KDPG aldolase activity|phospho-2-keto-3-deoxygluconic aldolase activity|ODPG aldolase activity|2-keto-3-deoxy-6-phosphogluconate aldolase activity|2-keto-3-deoxygluconate-6-P-aldolase activity|2-oxo-3-deoxy-6-phosphogluconate aldolase activity|phospho-2-dehydro-3-deoxygluconate aldolase activity				EC:4.1.2.14|MetaCyc:KDPGALDOL-RXN|RHEA:17089									molecular_function											owl:Class	
GO:0047339	biolink:NamedThing	nucleoside-triphosphate-hexose-1-phosphate nucleotidyltransferase activity	Catalysis of the reaction: hexose 1-phosphate + nucleoside triphosphate = NDP-hexose + diphosphate.	tmpzr1t_l9r_go_relaxed.owl	hexose-1-phosphate guanylyltransferase activity|NDP-hexose pyrophosphorylase activity|hexose 1-phosphate guanylyltransferase activity|nucleoside-triphosphate-aldose-1-phosphate nucleotidyltransferase activity|nucleoside diphosphohexose pyrophosphorylase activity|NTP:hexose-1-phosphate nucleotidyltransferase activity|NDP-hexose diphosphorylase activity|NDP hexose pyrophosphorylase activity|hexose nucleotidylating enzyme activity|GDP hexose pyrophosphorylase activity|hexose 1-phosphate nucleotidyltransferase activity|NTP:alpha-D-aldose-1-phosphate nucleotidyltransferase activity|guanosine diphosphohexose pyrophosphorylase activity|GTP:hexose-1-phosphate guanylyltransferase activity|GTP:alpha-D-hexose-1-phosphate guanylyltransferase activity				MetaCyc:2.7.7.28-RXN|EC:2.7.7.28							GO:0047340		molecular_function											owl:Class	
GO:1900137	biolink:NamedThing	negative regulation of chemokine activity	Any process that stops, prevents or reduces the frequency, rate or extent of chemokine activity.	tmpzr1t_l9r_go_relaxed.owl	downregulation of chemokine activity|down regulation of chemokine activity|down-regulation of chemokine activity|inhibition of chemokine activity							bf	2012-02-28T01:36:33Z					biological_process											owl:Class	
GO:0016005	biolink:NamedThing	phospholipase A2 activator activity	Increases the activity of the enzyme phospholipase A2.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0051509	biolink:NamedThing	tomatidine UDP-glucosyltransferase activity	Catalysis of the reaction: UDP-glucose + tomatidine = UDP + O-glucosyl-tomatidine.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0047433	biolink:NamedThing	branched-chain-2-oxoacid decarboxylase activity	Catalysis of the reaction: (S)-3-methyl-2-oxopentanoate + H(+) = 2-methylbutanal + CO(2).	tmpzr1t_l9r_go_relaxed.owl	branched-chain alpha-keto acid decarboxylase activity|(3S)-3-methyl-2-oxopentanoate carboxy-lyase activity|BCKA|branched-chain oxo acid decarboxylase activity|branched-chain keto acid decarboxylase activity|(3S)-3-methyl-2-oxopentanoate carboxy-lyase (2-methylbutanal-forming)				RHEA:21108|EC:4.1.1.72|KEGG_REACTION:R03894|MetaCyc:4.1.1.72-RXN									molecular_function											owl:Class	
GO:0070473	biolink:NamedThing	negative regulation of uterine smooth muscle contraction	Any process that decreases the frequency, rate or extent of uterine smooth muscle contraction.	tmpzr1t_l9r_go_relaxed.owl	down regulation of uterine smooth muscle contraction|down-regulation of uterine smooth muscle contraction|negative regulation of myometrial smooth muscle contraction|negative regulation of myometrial contraction|negative regulation of myometrium contraction|inhibition of uterine smooth muscle contraction|downregulation of uterine smooth muscle contraction|uterine smooth muscle relaxation													biological_process											owl:Class	
GO:0022819	biolink:NamedThing	potassium ion uniporter activity	Catalysis of the active transport of a potassium ion across a membrane by a mechanism involving conformational change, where energy for active transport is derived from membrane potential if the solute is charged.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1905506	biolink:NamedThing	gerontoplast stroma	Any plastid stroma that is part of a gerontoplast.	tmpzr1t_l9r_go_relaxed.owl								tb	2016-09-27T20:01:34Z					cellular_component											owl:Class	
GO:0033899	biolink:NamedThing	ribonuclease U2 activity	Catalysis of the two-stage endonucleolytic cleavage to nucleoside 3'-phosphates and 3'-phosphooligonucleotides ending in Ap or Gp with 2',3'-cyclic phosphate intermediates.	tmpzr1t_l9r_go_relaxed.owl	purine specific endoribonuclease activity|ribonuclease (purine) activity|purine-specific RNase activity|pleospora RNase activity|purine-specific ribonuclease activity|trichoderma koningi RNase III activity|RNase U2 activity				EC:4.6.1.20|MetaCyc:3.1.27.4-RXN									molecular_function											owl:Class	
GO:0047293	biolink:NamedThing	4-hydroxybenzoate nonaprenyltransferase activity	Catalysis of the reaction: p-hydroxybenzoate + solanesyl pyrophosphate = nonaprenyl-4-hydroxybenzoate + diphosphate.	tmpzr1t_l9r_go_relaxed.owl	p-hydroxybenzoate polyprenyltransferase activity|p-hydroxybenzoic acid-polyprenyl transferase activity|4-hydroxybenzoate transferase activity|p-hydroxybenzoic-polyprenyl transferase activity|p-hydroxybenzoate dimethylallyltransferase activity|solanesyl-diphosphate:4-hydroxybenzoate nonaprenyltransferase activity|nonaprenyl-4-hydroxybenzoate transferase activity				MetaCyc:2.5.1.39-RXN|RHEA:17709|EC:2.5.1.39									molecular_function											owl:Class	
GO:0052767	biolink:NamedThing	mannosyl-oligosaccharide 1,6-alpha-mannosidase activity	Catalysis of the hydrolysis of the alpha-(1->6) bonds of alpha-D-mannose residues in mannosyl-oligosaccharide.	tmpzr1t_l9r_go_relaxed.owl	1,6-alpha-mannosidase activity|alpha-1,6-mannosyl-oligosaccharide alpha-D-mannohydrolase activity|1,6-alpha-mannosyl-oligosaccharide alpha-D-mannohydrolase activity|alpha-1,6-mannosidase activity				EC:3.1.1.-			ai	2011-09-30T12:55:24Z					molecular_function											owl:Class	
GO:0009015	biolink:NamedThing	N-succinylarginine dihydrolase activity	Catalysis of the reaction: N(2)-succinyl-L-arginine + 2 H(2)O + 2 H(+) = N(2)-succinyl-L-ornithine + CO(2) + 2 NH(4)(+).	tmpzr1t_l9r_go_relaxed.owl	N2-succinylarginine dihydrolase activity|arginine succinylhydrolase activity|AruB|2-N-succinyl-L-arginine iminohydrolase (decarboxylating)|N2-succinyl-L-arginine iminohydrolase (decarboxylating)|SADH|succinylarginine dihydrolase activity|AstB				MetaCyc:SUCCARGDIHYDRO-RXN|KEGG_REACTION:R04189|EC:3.5.3.23|RHEA:19533									molecular_function											owl:Class	
GO:0097005	biolink:NamedThing	adipokinetic hormone receptor binding	Binding to an adipokinetic hormone receptor. Adipokinetic hormones (AKHs) are peptide hormones that are involved in the mobilization of sugar and lipids from the insect fat body during energy-requiring activities such as flight and locomotion. They also contribute to hemolymph sugar homeostasis.	tmpzr1t_l9r_go_relaxed.owl	AKH receptor binding							pr	2011-03-14T12:58:19Z					molecular_function											owl:Class	
GO:0018897	biolink:NamedThing	dibenzothiophene desulfurization	The removal of the sulfur atom from dibenzothiophene, a substance composed of two benzene rings linked by one sulfide bond and one carbon-carbon bond.	tmpzr1t_l9r_go_relaxed.owl	dibenzothiophene desulphurization				MetaCyc:PWY-681|UM-BBD_pathwayID:dbt									biological_process											owl:Class	
GO:0018542	biolink:NamedThing	2,3-dihydroxy DDT 1,2-dioxygenase activity	Catalysis of the reaction: 2,3-dihydroxy DDT + O2 = 6-oxo-2-hydroxy-7-(4-chlorophenyl)-3,8,8,8-tetrachloroocta-2E,4E-dienoate.	tmpzr1t_l9r_go_relaxed.owl					EC:1.13.11.-|UM-BBD_reactionID:r0452									molecular_function											owl:Class	
GO:0036333	biolink:NamedThing	hepatocyte homeostasis	Any biological process involved in the maintenance of the steady-state number of hepatocytes within a population of cells. Hepatocytes are specialized epithelial cells of the liver that are organized into interconnected plates called lobules.	tmpzr1t_l9r_go_relaxed.owl								bf	2012-09-05T10:17:07Z					biological_process											owl:Class	
GO:1903849	biolink:NamedThing	positive regulation of aorta morphogenesis	Any process that activates or increases the frequency, rate or extent of aorta morphogenesis.	tmpzr1t_l9r_go_relaxed.owl	activation of aorta morphogenesis|up regulation of aorta morphogenesis|up-regulation of aorta morphogenesis|upregulation of aorta morphogenesis							rph	2015-01-23T14:01:09Z					biological_process											owl:Class	
GO:0033980	biolink:NamedThing	phosphonopyruvate decarboxylase activity	Catalysis of the reaction: 3-phosphonopyruvate + 2 H(+) = CO(2) + phosphonoacetaldehyde.	tmpzr1t_l9r_go_relaxed.owl	3-phosphonopyruvate carboxy-lyase (2-phosphonoacetaldehyde-forming) activity|3-phosphonopyruvate carboxy-lyase activity				EC:4.1.1.82|KEGG_REACTION:R04053|MetaCyc:4.1.1.82-RXN|RHEA:20768									molecular_function											owl:Class	
GO:0052725	biolink:NamedThing	inositol-1,3,4-trisphosphate 6-kinase activity	Catalysis of the reaction: 1D-myo-inositol 1,3,4-trisphosphate + ATP = 1D-myo-inositol 1,3,4,6-tetrakisphosphate + ADP + 2 H(+).	tmpzr1t_l9r_go_relaxed.owl	inositol 1,3,4-trisphosphate 6-kinase activity|1D-myo-inositol-trisphosphate 6-kinase activity|inositol-trisphosphate 6-kinase activity|Ins(1,3,4)P3 6-kinase activity|IP3 6-kinase activity|ATP:1D-myo-inositol-1,3,4-trisphosphate 6-phosphotransferase activity|ins(1,3,4)P(3) 6-kinase activity				RHEA:20940|EC:2.7.1.159|Reactome:R-HSA-2267372|MetaCyc:2.7.1.133-RXN|Reactome:R-HSA-1855197			ai	2011-08-16T12:42:59Z					molecular_function											owl:Class	
GO:0021759	biolink:NamedThing	globus pallidus development	The progression of the globus pallidus over time from its initial formation until its mature state. The globus pallidus is one of the basal ganglia involved with control of voluntary movement in the brain.	tmpzr1t_l9r_go_relaxed.owl	pallidum development													biological_process											owl:Class	
GO:0102491	biolink:NamedThing	dGTP phosphohydrolase activity	Catalysis of the reaction: dGTP + 2 H2O = dGMP + 2 hydrogenphosphate + 2 H+.	tmpzr1t_l9r_go_relaxed.owl					EC:3.6.1.5|MetaCyc:RXN-14208									molecular_function											owl:Class	
GO:0036087	biolink:NamedThing	glutathione synthase complex	A protein complex composed of two or more polypeptide subunits, and which possesses glutathione synthase activity (catalysis of the reaction: L-gamma-glutamyl-L-cysteine + ATP + glycine = ADP + glutathione + 2 H(+) + phosphate). In eukaryotes, the complex is homodimeric, in E. coli glutathione synthase exists as a tetramer, and in S. pombe the complex exists as a homodimer or a heterotetramer.	tmpzr1t_l9r_go_relaxed.owl	glutathione synthetase complex							bf	2012-01-05T04:29:20Z					cellular_component											owl:Class	
GO:0017193	biolink:NamedThing	N-terminal peptidyl-glycine acetylation	The acetylation of the N-terminal glycine of proteins to form the derivative N-acetylglycine.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0046									biological_process											owl:Class	
GO:0031843	biolink:NamedThing	type 2 neuropeptide Y receptor binding	Binding to a type 2 neuropeptide Y receptor.	tmpzr1t_l9r_go_relaxed.owl	type 2 neuropeptide Y receptor ligand													molecular_function											owl:Class	
GO:0031841	biolink:NamedThing	neuropeptide Y receptor binding	Binding to a neuropeptide Y receptor.	tmpzr1t_l9r_go_relaxed.owl	neuropeptide Y receptor ligand|NPY receptor binding													molecular_function											owl:Class	
GO:0033562	biolink:NamedThing	co-transcriptional gene silencing by RNA interference machinery	A process in which the RNAi machinery mediates the degradation of nascent transcripts in association with chromatin.	tmpzr1t_l9r_go_relaxed.owl	co-transcriptional gene silencing by small RNA|cotranscriptional gene silencing by small RNA|RNAi-mediated CTGS|cotranscriptional gene silencing by RNA interference machinery|small RNA-mediated cotranscriptional gene silencing													biological_process											owl:Class	
GO:0018507	biolink:NamedThing	cis-3,4-dihydrophenanthrene-3,4-diol dehydrogenase activity	Catalysis of the reaction: (3S,4R)-3,4-dihydrophenanthrene-3,4-diol + NAD(+) = H(+) + NADH + phenanthrene-3,4-diol.	tmpzr1t_l9r_go_relaxed.owl	(+)-cis-3,4-dihydrophenanthrene-3,4-diol:NAD+ 3,4-oxidoreductase activity|cis-3,4-dihydroxy-3,4-dihydrophenanthrene dehydrogenase activity				UM-BBD_reactionID:r0488|MetaCyc:1.3.1.49-RXN|RHEA:16253|KEGG_REACTION:R04151|EC:1.3.1.49									molecular_function											owl:Class	
GO:1902013	biolink:NamedThing	poly(glycerol phosphate) teichoic acid metabolic process	The chemical reactions and pathways involving poly(glycerol phosphate) teichoic acid.	tmpzr1t_l9r_go_relaxed.owl	poly(glycerol phosphate) teichoic acid metabolism							tb	2013-03-22T15:43:45Z					biological_process											owl:Class	
GO:0001535	biolink:NamedThing	radial spoke head	Protein complex forming part of eukaryotic flagellar apparatus.	tmpzr1t_l9r_go_relaxed.owl	radial spokehead													cellular_component											owl:Class	
GO:0048309	biolink:NamedThing	endoplasmic reticulum inheritance	The partitioning of endoplasmic reticulum between daughter cells at cell division.	tmpzr1t_l9r_go_relaxed.owl	ER inheritance													biological_process											owl:Class	
GO:0102188	biolink:NamedThing	4alpha-methyl-5alpha-cholesta-7,24-dien-3beta-ol-4alpha-methyl oxidase activity	Catalysis of the reaction: 4alpha-methyl-5alpha-cholesta-7,24-dien-3beta-ol + O2 + NADH(2-) + H+ <=> 4alpha-hydroxymethyl-5alpha-cholesta-7,24-dien-3beta-ol + NAD(1-) + H2O.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-11956									molecular_function											owl:Class	
GO:0038006	biolink:NamedThing	netrin receptor activity involved in chemoattraction	Combining with a netrin signal and transmitting the signal from one side of the membrane to the other to contribute to the directed movement of a motile cell towards a higher concentration of netrin.	tmpzr1t_l9r_go_relaxed.owl	netrin receptor activity involved in positive chemotaxis|attractive netrin receptor activity							bf	2011-06-10T02:22:29Z					molecular_function											owl:Class	
GO:0031506	biolink:NamedThing	cell wall glycoprotein biosynthetic process	The chemical reactions and pathways resulting in the formation of cell wall glycoproteins, any cell wall protein that contains covalently bound sugar residues.	tmpzr1t_l9r_go_relaxed.owl	cell wall glycoprotein synthesis|cell wall glycoprotein formation|cell wall glycoprotein anabolism|cell wall glycoprotein biosynthesis													biological_process											owl:Class	
GO:0034022	biolink:NamedThing	3-(hydroxyamino)phenol mutase activity	Catalysis of the reaction: 3-hydroxyaminophenol = aminohydroquinone.	tmpzr1t_l9r_go_relaxed.owl	3-(hydroxyamino)phenol hydroxymutase activity|3-hydroxylaminophenol mutase activity|3HAP mutase activity				KEGG_REACTION:R06988|UM-BBD_enzymeID:e0953|RHEA:20577|EC:5.4.4.3|MetaCyc:5.4.4.3-RXN									molecular_function											owl:Class	
GO:0070431	biolink:NamedThing	nucleotide-binding oligomerization domain containing 2 signaling pathway	Any series of molecular signals generated as a consequence of binding to nucleotide-binding oligomerization domain containing 2 (NOD2).	tmpzr1t_l9r_go_relaxed.owl	nucleotide-binding oligomerization domain containing 2 signalling pathway|NOD2 signaling pathway													biological_process											owl:Class	
GO:0050275	biolink:NamedThing	scopoletin glucosyltransferase activity	Catalysis of the reaction: scopoletin + UDP-D-glucose = H(+) + scopolin + UDP.	tmpzr1t_l9r_go_relaxed.owl	UDPglucose:scopoletin glucosyltransferase activity|SGTase activity|UDPglucose:scopoletin O-beta-D-glucosyltransferase activity|UDP-glucose:scopoletin O-beta-D-glucosyltransferase activity|uridine diphosphoglucose-scopoletin glucosyltransferase activity				RHEA:20453|KEGG_REACTION:R03594|EC:2.4.1.128|MetaCyc:SCOPOLETIN-GLUCOSYLTRANSFERASE-RXN									molecular_function											owl:Class	
GO:0019802	biolink:NamedThing	cyclization of glutamine involved in intein-mediated protein splicing	The cyclization of glutamine to yield an L-glutamimide residue at the C-terminus of an excised intein during protein splicing.	tmpzr1t_l9r_go_relaxed.owl	cyclization of glutamine, during protein splicing				RESID:AA0303	Note that this term should not be confused with 'peptidyl-pyroglutamic acid biosynthesis, using glutaminyl-peptide cyclotransferase ; GO:0017186'. See also the biological process term 'intein-mediated protein splicing ; GO:0016539'.								biological_process											owl:Class	
GO:0043212	biolink:NamedThing	carbohydrate-exporting ABC transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + carbohydrate(in) -> ADP + phosphate + carbohydrate(out).	tmpzr1t_l9r_go_relaxed.owl	carbohydrate-exporting ATPase activity	https://github.com/geneontology/go-ontology/issues/17289												molecular_function											owl:Class	
GO:0031271	biolink:NamedThing	lateral pseudopodium assembly	The extension of a pseudopodium from the lateral area of a cell.	tmpzr1t_l9r_go_relaxed.owl	lateral pseudopodium formation													biological_process											owl:Class	
GO:0016540	biolink:NamedThing	protein autoprocessing	Processing which a protein carries out itself. This involves actions such as the autolytic removal of residues to generate the mature form of the protein.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0071005	biolink:NamedThing	U2-type precatalytic spliceosome	A spliceosomal complex that is formed by the recruitment of the preassembled U4/U6.U5 tri-snRNP to the prespliceosome. Although all 5 snRNPs are present, the precatalytic spliceosome is catalytically inactive. The precatalytic spliceosome includes many proteins in addition to those found in the U1, U2 and U4/U6.U5 snRNPs.	tmpzr1t_l9r_go_relaxed.owl	major precatalytic spliceosome|mammalian U2-type spliceosomal complex B|GT-AG precatalytic spliceosome|mammalian U2-type spliceosomal complex B1|yeast U12-type spliceosomal complex A2-1							mah	2009-07-30T12:00:35Z					cellular_component											owl:Class	
GO:1902396	biolink:NamedThing	protein localization to bicellular tight junction	A process in which a protein is transported to, or maintained in, a location within a bicellular tight junction.	tmpzr1t_l9r_go_relaxed.owl	protein localization in tight junction|protein localisation to tight junction|protein localisation in tight junction							tb	2013-09-11T21:43:13Z					biological_process											owl:Class	
GO:0005227	biolink:NamedThing	calcium activated cation channel activity	Enables the calcium concentration-regulatable energy-independent passage of cations across a lipid bilayer down a concentration gradient.	tmpzr1t_l9r_go_relaxed.owl	intracellular calcium-activated potassium channel|polycystin													molecular_function											owl:Class	
GO:0006965	biolink:NamedThing	positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria	Any process that activates or increases the frequency, rate, or extent of biosynthesis of antibacterial peptides active against Gram-positive bacteria.	tmpzr1t_l9r_go_relaxed.owl	stimulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria|upregulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria|anti-Gram-positive bacterial peptide induction|anti-Gram-positive bacterial polypeptide induction|up regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria|up-regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria|activation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria													biological_process											owl:Class	
GO:0047268	biolink:NamedThing	galactinol-raffinose galactosyltransferase activity	Catalysis of the reaction: raffinose + 1-alpha-D-galactosyl-myo-inositol = stachyose + myo-inositol.	tmpzr1t_l9r_go_relaxed.owl	alpha-D-(1->3)-galactosyl-myo-inositol:raffinose galactosyltransferase activity|stachyose synthetase activity				MetaCyc:2.4.1.67-RXN|RHEA:20776|EC:2.4.1.67									molecular_function											owl:Class	
GO:1904484	biolink:NamedThing	cloacal gland development	The process whose specific outcome is the progression of a cloacal gland over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl								mr	2015-07-15T22:14:39Z					biological_process											owl:Class	
GO:0004771	biolink:NamedThing	sterol esterase activity	Catalysis of the reaction: a steryl ester + H2O = a sterol + a fatty acid.	tmpzr1t_l9r_go_relaxed.owl	cholesterase activity|triterpenol esterase activity|sterol ester hydrolase activity|cholesterol ester hydrolase activity|cholesterol ester synthase activity|cholesteryl ester synthase activity|acylcholesterol lipase activity|steryl-ester acylhydrolase activity|cholesterol esterase activity|cholesteryl ester hydrolase activity|cholesteryl esterase activity				EC:3.1.1.13|Reactome:R-HSA-6813720|Reactome:R-HSA-8865667|RHEA:10100|Reactome:R-HSA-192417|MetaCyc:STEROL-ESTERASE-RXN									molecular_function											owl:Class	
GO:0140698	biolink:NamedThing	attachment of telomeric heterochromatin to nuclear envelope	The process in which physical connections are formed between sub-telomeric heterochromatin and the nuclear envelope facilitating bouquet formation.	tmpzr1t_l9r_go_relaxed.owl	attachment of telomeres to nuclear envelope|heterochromatin organization|attachment of telomeric chromatin to nuclear envelope	https://github.com/geneontology/go-ontology/issues/22043|https://github.com/geneontology/go-ontology/issues/22083						pg	2021-08-26T14:46:17Z					biological_process											owl:Class	
GO:0004509	biolink:NamedThing	steroid 21-monooxygenase activity	Catalysis of the reaction: A C(21) steroid + [reduced NADPH--hemoprotein reductase] + O(2) = a 21-hydroxy-C(21)-steroid + [oxidized NADPH--hemoprotein reductase] + H(2)O.	tmpzr1t_l9r_go_relaxed.owl	21-hydroxylase activity|cytochrome p450 XXIA1 activity|steroid,hydrogen-donor:oxygen oxidoreductase (21-hydroxylating)|cytochrome P450 CYP21A1|steroid 21-hydroxylase activity				EC:1.14.14.16|RHEA:65612|Reactome:R-HSA-193964|MetaCyc:STEROID-21-MONOOXYGENASE-RXN|Reactome:R-HSA-5601976|Reactome:R-HSA-193981									molecular_function											owl:Class	
GO:0110075	biolink:NamedThing	regulation of ferroptosis	Any process that modulates the frequency, rate or extent of ferroptosis.	tmpzr1t_l9r_go_relaxed.owl								kmv	2018-01-11T17:51:48Z					biological_process											owl:Class	
GO:0015018	biolink:NamedThing	galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity	Catalysis of the reaction: UDP-glucuronate + 3-beta-D-galactosyl-4-beta-D-galactosyl-O-beta-D-xylosylprotein = UDP + 3-beta-D-glucuronosyl-3-beta-D-galactosyl-4-beta-D-galactosyl-O-beta-D-xylosylprotein.	tmpzr1t_l9r_go_relaxed.owl	UDPglucuronate:3-beta-D-galactosyl-4-beta-D-galactosyl-O-beta-D-xylosyl-protein D-glucuronosyltransferase activity|UDP-glucuronate:3-beta-D-galactosyl-4-beta-D-galactosyl-O-beta-D-xylosyl-protein D-glucuronosyltransferase activity|glucuronosyltransferase I activity|uridine diphosphate glucuronic acid:acceptor glucuronosyltransferase activity				Reactome:R-HSA-1889955|RHEA:24168|EC:2.4.1.135|Reactome:R-HSA-3560802|MetaCyc:2.4.1.135-RXN|Reactome:R-HSA-9638064									molecular_function											owl:Class	
GO:0080070	biolink:NamedThing	8-methylthiooctyl-desulfoglucosinolate sulfotransferase activity	Catalysis of the reaction: 8-methylthiooctyl-desulfoglucosinolate + 3'-phosphoadenosine 5'-phosphosulfate = 8-methylthiooctyl-glucosinolate + adenosine 3',5'-bisphosphate.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXNQT-4333			dhl	2009-04-13T04:07:58Z					molecular_function											owl:Class	
GO:0036361	biolink:NamedThing	racemase activity, acting on amino acids and derivatives	Catalysis of the interconversion of the two enantiomers of a chiral amino acid or amino acid derivative.	tmpzr1t_l9r_go_relaxed.owl								bf	2012-09-21T11:13:47Z					molecular_function											owl:Class	
GO:0070264	biolink:NamedThing	transcription factor TFIIIE complex	A transcription factor complex that is involved in regulating transcription from RNA polymerase III (Pol III) promoters. TFIIIE contains a specific subset of ribosomal proteins.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0042392	biolink:NamedThing	sphingosine-1-phosphate phosphatase activity	Catalysis of the reaction: sphingosine 1-phosphate + H2O = sphingosine + phosphate.	tmpzr1t_l9r_go_relaxed.owl	SPPase activity|sphingosine-1-phosphate phosphohydrolase activity|SPP phosphatase activity				Reactome:R-HSA-428696|MetaCyc:RXN3DJ-25|Reactome:R-HSA-428690|Reactome:R-HSA-428701|RHEA:27518									molecular_function											owl:Class	
GO:0001006	biolink:NamedThing	RNA polymerase III type 3 promoter sequence-specific DNA binding	Binding to a sequence of DNA that is a part of a type 3 promoter that controls transcription by RNA polymerase III (Pol III). A type 3 Pol III promoter is composed of elements upstream of the transcription start site, including a TATA box. The human U6 snRNA gene has a type 3 promoter. Type 3 Pol III promoters have not been observed in S. cerevisiae.	tmpzr1t_l9r_go_relaxed.owl	RNA polymerase III type 3 promoter DNA binding							krc	2010-08-18T06:02:26Z			GO:0001032		molecular_function											owl:Class	
GO:1904813	biolink:NamedThing	ficolin-1-rich granule lumen	Any membrane-enclosed lumen that is part of a ficolin-1-rich granule.	tmpzr1t_l9r_go_relaxed.owl	membrane-enclosed lumen of ficolin granule|membrane-enclosed lumen of ficolin-1-rich granule|ficolin-1-rich granule membrane-enclosed lumen|membrane-enclosed lumen of ficolin-1 rich granule							mec	2015-11-13T11:58:20Z					cellular_component											owl:Class	
GO:0022849	biolink:NamedThing	glutamate-gated calcium ion channel activity	Enables the transmembrane transfer of a calcium ion by a channel that opens when glutamate has been bound by the channel complex or one of its constituent parts.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0047034	biolink:NamedThing	15-hydroxyicosatetraenoate dehydrogenase activity	Catalysis of the reaction: NAD(P)+ + (15S)-15-hydroxy-5,8,11-cis-13-trans-icosatetraenoate = NAD(P)H + H+ + 15-oxo-5,8,11-cis-13-trans-icosatetraenoate.	tmpzr1t_l9r_go_relaxed.owl	15-hydroxyeicosatetraenoate dehydrogenase activity|(15S)-15-hydroxy-5,8,11-cis-13-trans-icosatetraenoate:NAD(P)+ 15-oxidoreductase activity				Reactome:R-HSA-2161789|MetaCyc:1.1.1.232-RXN|EC:1.1.1.232									molecular_function											owl:Class	
GO:0010617	biolink:NamedThing	circadian regulation of calcium ion oscillation	Any process that modulates the concentration of cytosolic free calcium ion [Ca2+]cyt with a regularity of approximately 24 hours.	tmpzr1t_l9r_go_relaxed.owl	circadian regulation of Ca2+ oscillation|circadian regulation of cytosolic calcium ion homeostasis|circadian regulation of cytosolic free calcium ion oscillation|circadian regulation of [Ca2+]cyt oscillation													biological_process											owl:Class	
GO:0034269	biolink:NamedThing	discadenine catabolic process	The chemical reactions and pathways resulting in the breakdown of discadenine, (2S)-2-amino-4-{6-[(3-methylbut-2-en-1-yl)amino]-3H-purin-3-yl}butanoic acid.	tmpzr1t_l9r_go_relaxed.owl	discadenine catabolism|discadenine degradation|discadenine breakdown													biological_process											owl:Class	
GO:0043554	biolink:NamedThing	aerobic respiration, using arsenite as electron donor	The oxidation of arsenite to arsenate, using oxygen (O2) as the electron acceptor. Arsenite oxidase provides electrons to an electron carrier which transfers them to oxygen utilizing respiratory systems.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0033381	biolink:NamedThing	establishment of granzyme B localization to T cell secretory granule	The directed movement of the protease granzyme B to a location within a secretory granule in a T cell.	tmpzr1t_l9r_go_relaxed.owl	T-lymphocyte secretory granule storage of granzyme B|establishment of granzyme B localisation in T cell secretory granule|establishment of granzyme B localization in T lymphocyte secretory granule|establishment of granzyme B localization in T-lymphocyte secretory granule|establishment of granzyme B localization in T-cell secretory granule|establishment of granzyme B localization in T cell secretory granule													biological_process											owl:Class	
GO:0102817	biolink:NamedThing	caffeoyl-CoA:3-O-glucosyl-5-O-(caffeoylglucoside-3'-O-glucoside) 3'-O-hydroxycinnamoyltransferase activity	Catalysis of the reaction: delphinidin 3-O-glucosyl-5-O-(caffeoylglucoside-3'-O-glucoside) + caffeoyl-CoA <=> gentiodelphin + coenzyme A.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-8235									molecular_function											owl:Class	
GO:0043768	biolink:NamedThing	S-ribosylhomocysteine lyase activity	Catalysis of the reaction: S-(5-deoxy-D-ribos-5-yl)-L-homocysteine = (S)-4,5-dihydroxypentane-2,3-dione + L-homocysteine.	tmpzr1t_l9r_go_relaxed.owl	LuxS|ribosylhomocysteinase activity|S-(5-deoxy-D-ribos-5-yl)-L-homocysteine homocysteine-lyase [(4S)-4,5-dihydroxypentan-2,3-dione-forming]|S-ribosylhomocysteinase activity				EC:4.4.1.21|RHEA:17753|KEGG_REACTION:R01291|MetaCyc:RIBOSYLHOMOCYSTEINASE-RXN							GO:0019138		molecular_function											owl:Class	
GO:0097616	biolink:NamedThing	positive regulation by host of symbiont type IV pilus-dependent motility	Any process in which an organism activates, maintains or increases the frequency, rate or extent of the type IV pilus-dependent motility of a symbiont organism (i.e. the controlled movement of a bacterial cell which is dependent on the presence of type IV pili, and which includes social gliding motility and twitching motility). The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	positive regulation by host of bacterial type IV pilus-dependent motility							pr	2014-06-10T13:19:51Z					biological_process											owl:Class	
GO:0097615	biolink:NamedThing	modulation by host of symbiont type IV pilus-dependent motility	The process in which an organism effects a change in the type IV pilus-dependent motility of a symbiont organism (i.e. the controlled movement of a bacterial cell which is dependent on the presence of type IV pili, and which includes social gliding motility and twitching motility). The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	modulation by host of bacterial type IV pilus-dependent motility							pr	2014-06-10T13:17:13Z					biological_process											owl:Class	
GO:0031825	biolink:NamedThing	type 1F serotonin receptor binding	Binding to a type 1F serotonin receptor.	tmpzr1t_l9r_go_relaxed.owl	5-hydroxytryptamine 1F receptor binding|type 1F serotonin receptor ligand													molecular_function											owl:Class	
GO:0072563	biolink:NamedThing	endothelial microparticle	A blood microparticle that is derived from, and contains membrane receptors as well as other proteins characteristic of, an endothelial cell.	tmpzr1t_l9r_go_relaxed.owl								mah	2011-01-28T01:53:25Z					cellular_component											owl:Class	
GO:0060992	biolink:NamedThing	response to fungicide	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fungicide stimulus. Fungicides are chemicals used to kill fungi.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-01-13T08:05:58Z					biological_process											owl:Class	
GO:0060068	biolink:NamedThing	vagina development	The reproductive developmental process whose specific outcome is the progression of the vagina over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1901359	biolink:NamedThing	tungstate binding	Binding to tungstate.	tmpzr1t_l9r_go_relaxed.owl								crds	2012-09-14T08:33:56Z					molecular_function											owl:Class	
GO:0002116	biolink:NamedThing	semaphorin receptor complex	A stable binary complex of a neurophilin and a plexin, together forming a functional semaphorin receptor.	tmpzr1t_l9r_go_relaxed.owl	plexin-neurophilin complex													cellular_component											owl:Class	
GO:0016980	biolink:NamedThing	creatinase activity	Catalysis of the reaction: creatine + H(2)O = sarcosine + urea.	tmpzr1t_l9r_go_relaxed.owl	creatine amidinohydrolase activity				MetaCyc:CREATINASE-RXN|RHEA:22456|EC:3.5.3.3|KEGG_REACTION:R01566									molecular_function											owl:Class	
GO:0102493	biolink:NamedThing	wogonin 7-O-glucosyltransferase activity	Catalysis of the reaction: wogonin + UDP-alpha-D-glucose <=> wogonin 7-O-beta-D-glucoside + UDP + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-14239									molecular_function											owl:Class	
GO:0044027	biolink:NamedThing	hypermethylation of CpG island	An increase in the epigenetic methylation of cytosine and adenosine residues in a CpG island in DNA. CpG islands are genomic regions that contain a high frequency of the CG dinucleotide and are often associated with the transcription start site of genes.	tmpzr1t_l9r_go_relaxed.owl	DNA hypermethylation of CpG island													biological_process											owl:Class	
GO:0044026	biolink:NamedThing	DNA hypermethylation	An increase in the epigenetic methylation of cytosine and adenosine residues in DNA.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0016006	biolink:NamedThing	Nebenkern	A product of the fusion of the mitochondria during spermatogenesis. After the completion of meiosis the mitochondria of the spermatid collect along side the nucleus and fuse into two masses; these wrap around each other to produce the spherical Nebenkern. During flagellum elongation the Nebenkern unfolds and the two derivatives (major and minor mitochondrial derivatives) elongate down the axoneme.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/20737												cellular_component											owl:Class	
GO:0071980	biolink:NamedThing	cell surface adhesin-mediated gliding motility	Cell gliding that results from the actions of cell surface adhesin proteins that are propelled by membrane motor proteins.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-10-21T03:03:44Z					biological_process											owl:Class	
GO:0103003	biolink:NamedThing	oleate peroxygenase activity	Catalysis of the reaction: oleate + a lipid hydroperoxide <=> 9,10-epoxystearate + a lipid alcohol.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-9804									molecular_function											owl:Class	
GO:0047640	biolink:NamedThing	aldose 1-dehydrogenase activity	Catalysis of the reaction: D-aldose + NAD+ = D-aldonolactone + NADH.	tmpzr1t_l9r_go_relaxed.owl	D-aldose:NAD+ 1-oxidoreductase activity|aldose dehydrogenase activity|dehydrogenase, D-aldohexose				EC:1.1.1.121|MetaCyc:ALDOSE-1-DEHYDROGENASE-RXN|RHEA:15917									molecular_function											owl:Class	
GO:0008893	biolink:NamedThing	guanosine-3',5'-bis(diphosphate) 3'-diphosphatase activity	Catalysis of the reaction: guanosine 3',5'-bis(diphosphate) + H2O = guanosine 5'-diphosphate + diphosphate.	tmpzr1t_l9r_go_relaxed.owl	penta-phosphate guanosine-3'-pyrophosphohydrolase activity|(ppGpp)ase activity|penta-phosphate guanosine-3'-diphosphohydrolase activity|guanosine-3',5'-bis(diphosphate) 3'-diphosphohydrolase activity|PpGpp phosphohydrolase activity|PpGpp-3'-pyrophosphohydrolase activity|guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase activity|guanosine-3',5'-bis(diphosphate) 3'-pyrophosphatase activity				MetaCyc:PPGPPSYN-RXN|EC:3.1.7.2|RHEA:14253									molecular_function											owl:Class	
GO:0050254	biolink:NamedThing	rhodopsin kinase activity	Catalysis of the reaction: ATP + rhodopsin = ADP + phosphorhodopsin.	tmpzr1t_l9r_go_relaxed.owl	opsin kinase (phosphorylating) activity|GPCR kinase 1 activity|ATP:rhodopsin phosphotransferase activity|GRK7|G-protein-coupled receptor kinase 1 activity|GRK1|opsin kinase activity|STK14|RK|rhodopsin kinase (phosphorylating) activity|cone opsin kinase activity				EC:2.7.11.14|Reactome:R-HSA-2581474|MetaCyc:2.7.11.14-RXN|RHEA:23356									molecular_function											owl:Class	
GO:0019505	biolink:NamedThing	resorcinol metabolic process	The chemical reactions and pathways involving resorcinol (C6H4(OH)2), a benzene derivative with many applications, including dyes, explosives, resins and as an antiseptic.	tmpzr1t_l9r_go_relaxed.owl	1,3-dihydroxybenzene metabolic process|1,3-benzenediol metabolic process|resorcinol metabolism|1,3-benzenediol metabolism|1,3-dihydroxybenzene metabolism				MetaCyc:P343-PWY									biological_process											owl:Class	
GO:0120238	biolink:NamedThing	sperm glycocalyx	The carbohydrate rich layer at the outermost periphery of a sperm cell.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/19782						krc	2020-07-27T21:42:50Z					cellular_component											owl:Class	
GO:0019082	biolink:NamedThing	viral protein processing	Any protein maturation process achieved by the cleavage of a peptide bond or bonds within a viral protein.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0035230	biolink:NamedThing	cytoneme	A long, thin, polarized cell projection that contains actin and can extend for distances many times the diameter of the cell. Cytonemes represent extensions of cell cytoplasm and typically have a diameter of approximately 0.2um.	tmpzr1t_l9r_go_relaxed.owl	membrane nanotube				Wikipedia:Membrane_nanotube									cellular_component											owl:Class	
GO:0004776	biolink:NamedThing	succinate-CoA ligase (GDP-forming) activity	Catalysis of the reaction: GTP + succinate + CoA = GDP + succinyl-CoA + phosphate.	tmpzr1t_l9r_go_relaxed.owl	succinyl-CoA synthetase (GDP-forming) activity|succinate-phosphorylating enzyme|succinyl coenzyme A synthetase (guanosine diphosphate-forming) activity|G-STK|P-enzyme|succinyl CoA synthetase activity|succinate:CoA ligase (GDP-forming) activity|succinyl coenzyme A synthetase|succinyl coenzyme A synthetase (GDP-forming) activity|SCS|succinic thiokinase				EC:6.2.1.4|RHEA:22120|Reactome:R-HSA-71775|MetaCyc:SUCCINATE--COA-LIGASE-GDP-FORMING-RXN|KEGG_REACTION:R00432									molecular_function											owl:Class	
GO:0009575	biolink:NamedThing	chromoplast stroma	The space enclosed by the double membrane of a chromoplast but excluding the photosynthetic material.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0061029	biolink:NamedThing	eyelid development in camera-type eye	The progression of the eyelid in a camera-type eye from its formation to the mature state. The eyelid is a membranous cover that helps protect and lubricate the eye.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-02-09T09:36:11Z					biological_process											owl:Class	
GO:0038105	biolink:NamedThing	sequestering of TGFbeta from receptor via TGFbeta binding	Binding to a transforming growth factor-beta (TGFbeta) protein in the extracellular region, and inhibiting TGFbeta signaling by preventing TGFbeta from binding to its cell surface receptor.	tmpzr1t_l9r_go_relaxed.owl	extracellular sequestering of transforming growth factor-beta|extracellular sequestering of TGFbeta					This term is for annotation of gene products that bind to TGFbeta. For gene products that tether the TGFbeta-containing latency complex to the extracellular matrix, but do not necessarily bind TGF-beta directly, consider instead annotating to 'sequestering of TGFbeta in extracellular matrix ; GO:0035583'.		bf	2012-02-22T11:35:58Z					biological_process											owl:Class	
GO:1900728	biolink:NamedThing	cardiac neural crest cell delamination involved in outflow tract morphogenesis	Any cardiac neural crest cell delamination that is involved in outflow tract morphogenesis.	tmpzr1t_l9r_go_relaxed.owl								bf	2012-05-25T09:50:24Z					biological_process											owl:Class	
GO:0036036	biolink:NamedThing	cardiac neural crest cell delamination	The negative regulation of cell adhesion process in which a cardiac neural crest cell physically separates from the rest of the neural tube.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-11-02T05:23:29Z					biological_process											owl:Class	
GO:0008828	biolink:NamedThing	dATP pyrophosphohydrolase activity	Catalysis of the reaction: deoxy-ATP + H2O = dAMP + diphosphate.	tmpzr1t_l9r_go_relaxed.owl	2-hydroxy-(deoxy)adenosine-triphosphate pyrophosphatase activity|2-hydroxy-(d)ATP pyrophosphatase activity|2-hydroxy-adenosine triphosphate pyrophosphatase activity|2-hydroxy-ATP pyrophosphatase activity	https://github.com/geneontology/go-ontology/issues/20656			Reactome:R-HSA-2395872|MetaCyc:RXN0-384|Reactome:R-HSA-2395818|EC:3.6.1.56			jl	2012-10-18T13:22:38Z			GO:0044713|GO:0044714		molecular_function											owl:Class	
GO:0061139	biolink:NamedThing	bud field specification	The regionalization process in which the identity of a bud primordium is specified. Identity is considered to be the aggregate of characteristics by which a structure is recognized.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-05-25T09:21:01Z					biological_process											owl:Class	
GO:0021876	biolink:NamedThing	Notch signaling pathway involved in forebrain neuroblast division	The series of molecular signals initiated by binding of an extracellular ligand to a Notch receptor on the surface of the target cell that contributes to the self renewal of neuroblasts in the forebrain.	tmpzr1t_l9r_go_relaxed.owl	Notch signalling pathway in forebrain neuroblast division													biological_process											owl:Class	
GO:0050476	biolink:NamedThing	acetylenedicarboxylate decarboxylase activity	Catalysis of the reaction: H2O + acetylenedicarboxylate = CO2 + pyruvate.	tmpzr1t_l9r_go_relaxed.owl	acetylenedicarboxylate carboxy-lyase (pyruvate-forming)|acetylenedicarboxylate carboxy-lyase activity|acetylenedicarboxylate hydrase activity|acetylenedicarboxylate hydratase activity				EC:4.1.1.78|RHEA:17733|MetaCyc:4.1.1.78-RXN									molecular_function											owl:Class	
GO:0003236	biolink:NamedThing	sinus venosus morphogenesis	The process in which the sinus venosus is generated and organized. The sinus venosus is a heart chamber attached to the atrium on the venous side of the embryonic heart.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-10-13T11:16:52Z					biological_process											owl:Class	
GO:1903093	biolink:NamedThing	regulation of protein K48-linked deubiquitination	Any process that modulates the frequency, rate or extent of protein K48-linked deubiquitination.	tmpzr1t_l9r_go_relaxed.owl								bf	2014-06-03T12:27:48Z					biological_process											owl:Class	
GO:0035784	biolink:NamedThing	nickel cation homeostasis	Any process involved in the maintenance of an internal steady state of nickel cations within an organism or cell.	tmpzr1t_l9r_go_relaxed.owl	nickel homeostasis							bf	2011-04-05T09:55:14Z					biological_process											owl:Class	
GO:0000224	biolink:NamedThing	peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity	Catalysis of the reaction: 4-N-(N-acetyl-D-glucosaminyl)-protein + H2O = N-acetyl-beta-D-glucosaminylamine + peptide L-aspartate. This reaction is the hydrolysis of an N4-(acetyl-beta-D-glucosaminyl)asparagine residue in which the N-acetyl-D-glucosamine residue may be further glycosylated, to yield a (substituted) N-acetyl-beta-D-glucosaminylamine and the peptide containing an aspartic residue.	tmpzr1t_l9r_go_relaxed.owl	glycopeptide N-glycosidase activity|PNGase|glycopeptidase activity|peptide:N-glycanase|N-linked-glycopeptide-(N-acetyl-beta-D-glucosaminyl)-L-asparagine amidohydrolase activity|N-oligosaccharide glycopeptidase activity|jack-bean glycopeptidase|N-glycanase activity|PNGase A|PNGase F				EC:3.5.1.52|Reactome:R-HSA-8850594|MetaCyc:3.5.1.52-RXN									molecular_function											owl:Class	
GO:0046356	biolink:NamedThing	acetyl-CoA catabolic process	The chemical reactions and pathways resulting in the breakdown of acetyl-CoA, a derivative of coenzyme A in which the sulfhydryl group is acetylated.	tmpzr1t_l9r_go_relaxed.owl	acetyl-CoA breakdown|acetyl-CoA catabolism|acetyl-CoA degradation													biological_process											owl:Class	
GO:0019918	biolink:NamedThing	peptidyl-arginine methylation, to symmetrical-dimethyl arginine	The process of methylation of peptidyl-arginine to form peptidyl-N(omega),N'(omega)-dimethyl-L-arginine.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0067|RESID:AA0069									biological_process											owl:Class	
GO:0001522	biolink:NamedThing	pseudouridine synthesis	The intramolecular conversion of uridine to pseudouridine within an RNA molecule. This posttranscriptional base modification occurs in tRNA, rRNA, and snRNAs.	tmpzr1t_l9r_go_relaxed.owl	pseudouridylation				Wikipedia:Pseudouridylation|Wikipedia:Pseudouridine									biological_process											owl:Class	
GO:0032487	biolink:NamedThing	regulation of Rap protein signal transduction	Any process that modulates the frequency, rate or extent of Rap protein signal transduction.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0032486	biolink:NamedThing	Rap protein signal transduction	A series of molecular signals within the cell that are mediated by a member of the Rap family of proteins switching to a GTP-bound active state.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0061266	biolink:NamedThing	mesonephric interstitial fibroblast differentiation	The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the interstitial fibroblasts of the mesonephros as it progresses from its formation to the mature state.	tmpzr1t_l9r_go_relaxed.owl	mesonephros interstitial cell differentiation							dph	2010-08-30T03:12:17Z					biological_process											owl:Class	
GO:1902602	biolink:NamedThing	aluminum ion transmembrane transport	The process in which an aluminium ion is transported across a membrane.	tmpzr1t_l9r_go_relaxed.owl	aluminium transmembrane transport|aluminum transmembrane transport|aluminium ion transmembrane transport							pr	2013-12-20T11:09:01Z					biological_process											owl:Class	
GO:0071791	biolink:NamedThing	chemokine (C-C motif) ligand 5 binding	Binding to chemokine (C-C motif) ligand 5.	tmpzr1t_l9r_go_relaxed.owl	Regulated upon Activation, Normal T-cell Expressed, and Secreted binding|CCL5 binding|RANTES binding							mah	2010-09-01T02:28:22Z					molecular_function											owl:Class	
GO:0042953	biolink:NamedThing	lipoprotein transport	The directed movement of any conjugated, water-soluble protein in which the nonprotein group consists of a lipid or lipids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0086088	biolink:NamedThing	voltage-gated potassium channel activity involved in Purkinje myocyte action potential repolarization	Enables the transmembrane transfer of a potassium ion by a voltage-gated channel through the plasma membrane of a Purkinje myocyte contributing to the repolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.	tmpzr1t_l9r_go_relaxed.owl								dph	2011-11-22T01:32:02Z					molecular_function											owl:Class	
GO:0043595	biolink:NamedThing	endospore cortex	A layer surrounding a bacterial endospore found inside the outer endospore membrane, but outside the membrane surrounding the endospore core. It consists of peptidoglycan of a different chemical nature than that found in vegetative cell walls which results in less cross-linking of peptidoglycan.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0007481	biolink:NamedThing	haltere disc morphogenesis	The process in which the anatomical structures derived from the haltere disc are generated and organized. This includes the transformation of a haltere imaginal disc from a monolayered epithelium in the larvae of holometabolous insects into the recognizable adult capitellum, pedicel, haltere sclerite, metathoracic spiracle and metanotum.	tmpzr1t_l9r_go_relaxed.owl	haltere disc metamorphosis													biological_process											owl:Class	
GO:0046922	biolink:NamedThing	peptide-O-fucosyltransferase activity	Catalysis of the transfer of an alpha-L-fucosyl residue from GDP- beta-L-fucose to the serine hydroxy group of a protein acceptor.	tmpzr1t_l9r_go_relaxed.owl	GDP-beta-L-fucose:polypeptide O-alpha-L-fucosyltransferase activity|GDP-L-fucose:polypeptide fucosyltransferase activity|GDP-fucose protein O-fucosyltransferase activity|GDP-fucose:polypeptide fucosyltransferase activity				MetaCyc:2.4.1.221-RXN|EC:2.4.1.221|Reactome:R-HSA-5173192|Reactome:R-HSA-1912349									molecular_function											owl:Class	
GO:0036066	biolink:NamedThing	protein O-linked fucosylation	The process of transferring a fucosyl group to a serine or threonine residues in a protein acceptor molecule, to form an O-linked protein-sugar linkage.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-12-15T11:17:20Z					biological_process											owl:Class	
GO:0051131	biolink:NamedThing	chaperone-mediated protein complex assembly	The aggregation, arrangement and bonding together of a set of components to form a protein complex, mediated by chaperone molecules that do not form part of the finished complex.	tmpzr1t_l9r_go_relaxed.owl	cellular chaperone-mediated protein complex assembly|chaperone activity|protein complex assembly, multichaperone pathway											GO:0034619		biological_process											owl:Class	
GO:0090380	biolink:NamedThing	seed trichome maturation	A developmental process, independent of morphogenetic (shape) change, that is required for a seed trichome to attain its fully functional state.	tmpzr1t_l9r_go_relaxed.owl						These processes continue to 60 DPA in Gossypium spp.		tb	2010-09-15T02:29:42Z					biological_process											owl:Class	
GO:0008065	biolink:NamedThing	establishment of blood-nerve barrier	The establishment of the barrier between the perineurium of peripheral nerves and the vascular endothelium of endoneurial capillaries. The perineurium acts as a diffusion barrier, but ion permeability at the blood-nerve barrier is still higher than at the blood-brain barrier.	tmpzr1t_l9r_go_relaxed.owl	establishment of blood/nerve barrier													biological_process											owl:Class	
GO:0070589	biolink:NamedThing	cellular component macromolecule biosynthetic process	The chemical reactions and pathways resulting in the formation of a macromolecule that is destined to form part of a specific cellular component.	tmpzr1t_l9r_go_relaxed.owl	cellular component macromolecule biosynthesis							mah	2009-04-28T11:01:25Z					biological_process											owl:Class	
GO:0042019	biolink:NamedThing	interleukin-23 binding	Binding to interleukin-23.	tmpzr1t_l9r_go_relaxed.owl	IL-23 binding													molecular_function											owl:Class	
GO:0048756	biolink:NamedThing	sieve cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a sieve cell. A sieve cell is a type of sieve element that has relatively undifferentiated sieve areas (with narrow pores). The sieve areas are rather uniform in structure on all walls; that is, there are no sieve plates. Typical of gymnosperms and lower vascular plants. The sieve element is the cell in the phloem tissue concerned with mainly longitudinal conduction of food materials.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0060228	biolink:NamedThing	phosphatidylcholine-sterol O-acyltransferase activator activity	Increases the activity of phosphatidylcholine-sterol O-acyltransferase, an enzyme that converts cholesterol and phosphatidylcholine (lecithins) to cholesteryl esters and lyso-phosphatidylcholines.	tmpzr1t_l9r_go_relaxed.owl	LCAT activator activity													molecular_function											owl:Class	
GO:0005344	biolink:NamedThing	oxygen carrier activity	Binding to oxygen and delivering it to an acceptor molecule or a specific location.	tmpzr1t_l9r_go_relaxed.owl	hemocyanin|hemerythrin|oxygen-carrying|globin	https://github.com/geneontology/go-ontology/issues/17399										GO:0015033		molecular_function											owl:Class	
GO:0021950	biolink:NamedThing	chemorepulsion involved in precerebellar neuron migration	The creation and reception of signals that repel a precerebellar neuron as a component of the process of tangential migration.	tmpzr1t_l9r_go_relaxed.owl	negative chemotaxis involved in precerebellar neuron migration													biological_process											owl:Class	
GO:0043846	biolink:NamedThing	DNA polymerase III, clamp loader complex	A heptamer that includes the tau and gamma products of the dnaX gene and the chi/psi subcomplex. Confers structural asymmetry that allows the polymerase to replicate both leading and lagging strands.	tmpzr1t_l9r_go_relaxed.owl	DNA polymerase III, DnaX subcomplex|clamp loader complex|DNA polymerase III, DnaX complex													cellular_component											owl:Class	
GO:0090014	biolink:NamedThing	leaflet formation	The developmental process pertaining to the initial formation of a leaflet from unspecified parts. A leaflet is one of the ultimate segments of a compound leaf.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-07-29T11:05:37Z					biological_process											owl:Class	
GO:0009410	biolink:NamedThing	response to xenobiotic stimulus	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a xenobiotic, a compound foreign to the organim exposed to it. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical.	tmpzr1t_l9r_go_relaxed.owl	drug resistance|drug susceptibility/resistance|response to drug	https://github.com/geneontology/go-ontology/issues/19460										GO:0042493|GO:0017104|GO:0017035		biological_process											owl:Class	
GO:0099007	biolink:NamedThing	extrinsic component of presynaptic endosome membrane	The component of the presynaptic endosome membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0016062	biolink:NamedThing	adaptation of rhodopsin mediated signaling	The process in which a rhodopsin-mediated signaling pathway is adjusted to modulate the sensitivity and response of a visual system to light stimuli (that might vary over more than 6 magnitudes in intensity) without response saturation.	tmpzr1t_l9r_go_relaxed.owl	adaptation of rhodopsin mediated signalling													biological_process											owl:Class	
GO:0009331	biolink:NamedThing	glycerol-3-phosphate dehydrogenase complex	An enzyme complex that catalyzes the dehydrogenation of sn-glycerol 3-phosphate to form glycerone phosphate.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0031604	biolink:NamedThing	nuclear proteasome core complex, alpha-subunit complex	The subunits forming the outer ring of the core complex of a proteasome located in the nucleus of a cell.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0006035	biolink:NamedThing	cuticle chitin biosynthetic process	The chemical reactions and pathways resulting in the formation of cuticle chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues, found in cuticles.	tmpzr1t_l9r_go_relaxed.owl	cuticle chitin anabolism|cuticle chitin biosynthesis|cuticle chitin formation|cuticle chitin synthesis													biological_process											owl:Class	
GO:0033686	biolink:NamedThing	positive regulation of luteinizing hormone secretion	Any process that activates or increases the frequency, rate or extent of the regulated release of luteinizing hormone.	tmpzr1t_l9r_go_relaxed.owl	activation of luteinizing hormone secretion|up-regulation of luteinizing hormone secretion|upregulation of luteinizing hormone secretion|stimulation of luteinizing hormone secretion|up regulation of luteinizing hormone secretion													biological_process											owl:Class	
GO:0035201	biolink:NamedThing	leg disc anterior/posterior lineage restriction	Formation and/or maintenance of a lineage boundary between anterior and posterior compartments of the leg disc that cells cannot cross, thus separating the populations of cells in each compartment.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0003004	biolink:NamedThing	follicular fluid formation in ovarian follicle antrum involved in distinct antral spaces stage	The menstrual cycle process in which one central cavity separating the oocyte/cumulus complex from mural granulosa and theca cells is formed as part of the antral spaces stage of oogenesis.	tmpzr1t_l9r_go_relaxed.owl	follicular fluid formation in ovarian follicle antrum during distinct antral spaces stage													biological_process											owl:Class	
GO:0003335	biolink:NamedThing	corneocyte development	The process whose specific outcome is the progression of the corneocyte over time, from its formation to the mature structure. A corneocyte is the last stage of development of a keratinocyte where the keratinocyte flattens, loses its nucleus and eventually delaminates from the epidermis.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-11-24T09:01:02Z					biological_process											owl:Class	
GO:0001548	biolink:NamedThing	follicular fluid formation in ovarian follicle antrum	The menstrual cycle process that results in the formation of one central cavity separating the oocyte/cumulus complex from mural granulosa and theca cells during the various stages of oogenesis.	tmpzr1t_l9r_go_relaxed.owl	ovarian follicle antrum/follicular fluid biosynthesis|ovarian follicle antrum/follicular fluid formation													biological_process											owl:Class	
GO:0001769	biolink:NamedThing	establishment of B cell polarity	The directed orientation of B cell signaling molecules and associated membrane rafts towards a chemokine gradient of a contact point with an antigen displaying cell.	tmpzr1t_l9r_go_relaxed.owl	establishment of B-cell polarity|establishment of B-lymphocyte polarity|B cell polarization|B lymphocyte polarization|establishment of B lymphocyte polarity|B-cell polarization					Note that 'antigen displaying cell' in this term encompasses cell types such as follicular dendritic cells which display the unprocessed antigens of a B cell, leading to activation of the B cells and antigen uptake and processing by the B cells.								biological_process											owl:Class	
GO:0061563	biolink:NamedThing	trigeminal ganglion structural organization	The process that contributes to creating the structural organization of the trigeminal ganglion This process pertains to the physical shaping of a rudimentary structure.	tmpzr1t_l9r_go_relaxed.owl	trigeminal ganglia organization							dph	2013-07-10T09:12:11Z					biological_process											owl:Class	
GO:0070289	biolink:NamedThing	extracellular ferritin complex	A ferritin complex located in the extracellular region. Extracellular ferritin complexes contain L (light) chains but few or no H (heavy) chains.	tmpzr1t_l9r_go_relaxed.owl	serum ferritin complex													cellular_component											owl:Class	
GO:0031395	biolink:NamedThing	bursicon neuropeptide hormone complex	A neuropeptide hormone secreted by the central nervous system of insects that stimulates the tanning and sclerotization of the adult cuticle following eclosion. The active hormone consists of an obligate heterodimer of the alpha and beta subunits.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0003148	biolink:NamedThing	outflow tract septum morphogenesis	The process in which the anatomical structures of the outflow tract septum are generated and organized. The outflow tract septum is a partition in the outflow tract.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-09-22T07:51:01Z					biological_process											owl:Class	
GO:0060087	biolink:NamedThing	relaxation of vascular associated smooth muscle	A negative regulation of smooth muscle contraction resulting in relaxation of vascular smooth muscle. The relaxation is mediated by a decrease in the phosphorylation state of myosin light chain. This can be achieved by removal of calcium from the cytoplasm to the sarcoplasmic reticulum lumen through the action of Ca2+ ATPases leading to a decrease myosin light chain kinase activity, and through calcium-independent pathways leading to a increase in myosin light chain phosphatase activity.	tmpzr1t_l9r_go_relaxed.owl	relaxation of vascular smooth muscle|negative regulation of relaxation of vascular smooth muscle|positive regulation of relaxation of vascular smooth muscle|vascular smooth muscle relaxation|regulation of relaxation of vascular smooth muscle											GO:1905659|GO:1905657|GO:1905658		biological_process											owl:Class	
GO:0036132	biolink:NamedThing	13-prostaglandin reductase activity	Catalysis of the reaction: 15-keto-prostaglandin + NAD(P)H + H+ -> 13,14-dihydro-15-keto-prostaglandin + NAD(P)+. This reaction is the reduction of 15-keto-prostaglandin.	tmpzr1t_l9r_go_relaxed.owl	15-oxo-delta13-prostaglandin reductase activity|prostaglandin 13-reductase activity|delta13-15-ketoprostaglandin reductase activity|15-oxoprostaglandin 13-reductase activity|15-ketoprostaglandin delta13-reductase activity|prostaglandin delta13-reductase activity				EC:1.3.1.48|KEGG_REACTION:R04557|KEGG_REACTION:R04556|Reactome:R-HSA-2161692	Note that this is the reverse of the reaction described in '15-oxoprostaglandin 13-oxidase activity ; GO:0047522'.		bf	2012-03-05T10:42:22Z					molecular_function											owl:Class	
GO:0000472	biolink:NamedThing	endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	Endonucleolytic cleavage between the 5'-External Transcribed Spacer (5'-ETS) and the 5' end of the SSU-rRNA of a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, the 5.8S rRNA, and the Large Subunit (LSU) rRNA in that order from 5' to 3' along the primary transcript, to produce the mature end of the SSU-rRNA.	tmpzr1t_l9r_go_relaxed.owl	endonucleolytic cleavage at A1													biological_process											owl:Class	
GO:0034974	biolink:NamedThing	Swi5-Swi2 complex	A protein complex involved that contains proteins known in Schizosaccharomyces as Swi5 monomers and Swi2, and is involved in mating type switching.	tmpzr1t_l9r_go_relaxed.owl	Swi5 complex					Note that this term refers to Schizosaccharomyces pombe Swi5 and Swi2, which should not be confused with the unrelated Saccharomyces Swi5p and Swi2p.								cellular_component											owl:Class	
GO:1905014	biolink:NamedThing	positive regulation of 'de novo' NAD biosynthetic process from tryptophan	Any process that activates or increases the frequency, rate or extent of 'de novo' NAD biosynthetic process from tryptophan.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of 'de novo' NAD biosynthetic process from tryptophan|upregulation of 'de novo' NAD biosynthetic process from tryptophan|up-regulation of de novo NAD biosynthetic process from tryptophan|up regulation of de novo NAD biosynthetic process from tryptophan|up regulation of 'de novo' NAD biosynthetic process from tryptophan|activation of 'de novo' NAD biosynthetic process from tryptophan|activation of de novo NAD biosynthetic process from tryptophan|upregulation of de novo NAD biosynthetic process from tryptophan|positive regulation of de novo NAD biosynthetic process from tryptophan							bf	2016-03-03T10:01:10Z					biological_process											owl:Class	
GO:0019044	biolink:NamedThing	maintenance of viral latency	The perpetuation of a latent state, generally by repressing the viruses own lytic genes expression and ensuring expression of viral genes which function to keep the viral genome from being detected by the host defense mechanisms.	tmpzr1t_l9r_go_relaxed.owl	provirus maintenance|latent virus maintenance|prophage maintenance											GO:0032360|GO:0075716		biological_process											owl:Class	
GO:0044479	biolink:NamedThing	envenomation resulting in modulation of mast cell degranulation in other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant modulation of blood mast cell degranulation in the bitten organism.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-01-19T02:51:51Z					biological_process											owl:Class	
GO:0050885	biolink:NamedThing	neuromuscular process controlling balance	Any process that an organism uses to control its balance, the orientation of the organism (or the head of the organism) in relation to the source of gravity. In humans and animals, balance is perceived through visual cues, the labyrinth system of the inner ears and information from skin pressure receptors and muscle and joint receptors.	tmpzr1t_l9r_go_relaxed.owl	regulation of balance													biological_process											owl:Class	
GO:0016282	biolink:NamedThing	eukaryotic 43S preinitiation complex	A protein complex composed of the 40S ribosomal subunit plus eIF1A, eIF3, and eIF2-GTP-bound methionyl-initiator methionine tRNA.	tmpzr1t_l9r_go_relaxed.owl	eukaryotic 43S pre-initiation complex													cellular_component											owl:Class	
GO:0022627	biolink:NamedThing	cytosolic small ribosomal subunit	The small subunit of a ribosome located in the cytosol.	tmpzr1t_l9r_go_relaxed.owl	prokaryotic small ribosomal subunit|40S ribosomal subunit|eukaryotic ribosomal SSU|30S ribosomal subunit											GO:0005843|GO:0030873|GO:0009283|GO:0030499		cellular_component											owl:Class	
GO:2000952	biolink:NamedThing	negative regulation of xyloglucan catabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of xyloglucan catabolic process.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of xyloglucan catabolism							tt	2011-08-01T02:20:21Z					biological_process											owl:Class	
GO:0070942	biolink:NamedThing	neutrophil mediated cytotoxicity	The directed killing of a target cell by a neutrophil.	tmpzr1t_l9r_go_relaxed.owl	neutrophil mediated cell killing							mah	2009-10-01T01:49:30Z					biological_process											owl:Class	
GO:0071910	biolink:NamedThing	determination of liver left/right asymmetry	Determination of the asymmetric location of the liver with respect to the left and right halves of the organism.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-09-22T10:26:47Z					biological_process											owl:Class	
GO:0060791	biolink:NamedThing	sebaceous gland placode formation	The developmental process in which a sebaceous gland placode forms. A sebaceous gland placode is a thickening of the ectoderm that will give rise to the sebaceous gland bud.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-08-04T12:23:09Z					biological_process											owl:Class	
GO:0061102	biolink:NamedThing	stomach neuroendocrine cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a neuroendocrine cell of the stomach epithelium.	tmpzr1t_l9r_go_relaxed.owl	gastric neuroendocrine cell differentiation							dph	2010-04-28T09:47:07Z					biological_process											owl:Class	
GO:0043272	biolink:NamedThing	ethylene biosynthesis involved in jasmonic acid and ethylene-dependent systemic resistance	The chemical reactions and pathways resulting in the formation of ethylene (C2-H4, ethene), occurring as part of the process of jasmonic acid and ethylene-dependent systemic resistance.	tmpzr1t_l9r_go_relaxed.owl	ethylene formation during jasmonic acid and ethylene-dependent systemic resistance|ethylene synthesis during jasmonic acid and ethylene-dependent systemic resistance|ethylene anabolism during jasmonic acid and ethylene-dependent systemic resistance|ethylene biosynthetic process during jasmonic acid and ethylene-dependent systemic resistance													biological_process											owl:Class	
GO:0000938	biolink:NamedThing	GARP complex	A quatrefoil tethering complex required for retrograde traffic from the early endosome back to the late Golgi and biogenesis of cytoplasmic vesicles.	tmpzr1t_l9r_go_relaxed.owl	VFT tethering complex|Golgi associated retrograde protein complex|Vps fifty three tethering complex													cellular_component											owl:Class	
GO:0016027	biolink:NamedThing	inaD signaling complex	A complex of proteins that are involved in phototransduction and attached to the transient receptor potential (TRP) channel. The protein connections are mediated through inaD.	tmpzr1t_l9r_go_relaxed.owl	inaD signalling complex													cellular_component											owl:Class	
GO:1901208	biolink:NamedThing	negative regulation of heart looping	Any process that stops, prevents or reduces the frequency, rate or extent of heart looping.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of heart looping|negative regulation of cardiac looping|down regulation of heart looping|down-regulation of cardiac looping|inhibition of heart looping|downregulation of heart looping|downregulation of cardiac looping|down regulation of cardiac looping|inhibition of cardiac looping							rl	2012-07-31T07:16:10Z					biological_process											owl:Class	
GO:0000811	biolink:NamedThing	GINS complex	A heterotetrameric protein complex that associates with replication origins, where it is required for the initiation of DNA replication, and with replication forks.	tmpzr1t_l9r_go_relaxed.owl	Go, Ichi, Ni and San complex													cellular_component											owl:Class	
GO:0051936	biolink:NamedThing	gamma-aminobutyric acid reuptake	The uptake of gamma-aminobutyric acid (GABA, 4-aminobutyrate) by neurons or glial cells. This process leads to inactivation and recycling of neurotransmitters.	tmpzr1t_l9r_go_relaxed.owl	gamma-aminobutyric acid import into neuron|GABA recycling|gamma-aminobutyric acid uptake during transmission of nerve impulse|GABA import into glial cell|GABA reuptake|gamma-aminobutyric acid import into glial cell|GABA import into neuron|gamma-aminobutyric acid recycling|gamma-aminobutyric acid uptake involved in synaptic transmission													biological_process											owl:Class	
GO:0031615	biolink:NamedThing	cytosolic proteasome regulatory particle, lid subcomplex	The subcomplex of the cytosolic proteasome regulatory particle that forms the peripheral lid, which is added on top of the base subcomplex.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:1902280	biolink:NamedThing	regulation of RNA helicase activity	Any process that modulates the frequency, rate or extent of ATP-dependent RNA helicase activity.	tmpzr1t_l9r_go_relaxed.owl	regulation of ATP-dependent RNA helicase activity							rb	2013-07-03T18:05:19Z					biological_process											owl:Class	
GO:0048452	biolink:NamedThing	petal structural organization	The process that contributes to the act of creating the structural organization of the petal. This process pertains to the physical shaping of a rudimentary structure.	tmpzr1t_l9r_go_relaxed.owl	petal structural organisation											GO:0048420		biological_process											owl:Class	
GO:0098510	biolink:NamedThing	sensory perception of high humidity	The series of events required for an organism to detect high environmental humidity, convert this detection into a molecular signal, and recognize and characterize the signal. This is a neurological process.	tmpzr1t_l9r_go_relaxed.owl								dos	2013-09-25T13:57:27Z					biological_process											owl:Class	
GO:0009382	biolink:NamedThing	imidazoleglycerol-phosphate synthase complex	Complex that possesses imidazoleglycerol-phosphate synthase activity.	tmpzr1t_l9r_go_relaxed.owl	imidazoleglycerol phosphate synthase complex					See also the molecular function term 'imidazoleglycerol-phosphate synthase activity ; GO:0000107'.								cellular_component											owl:Class	
GO:0009833	biolink:NamedThing	plant-type primary cell wall biogenesis	A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of cellulose and pectin-containing cell walls that form adjacent to the middle lamella following cell division and during cell expansion. An example of this is found in Arabidopsis thaliana.	tmpzr1t_l9r_go_relaxed.owl	cellulose and pectin-containing primary cell wall biogenesis|primary cell wall biogenesis|primary cell wall formation|primary cell wall biosynthetic process|primary cell wall anabolism|primary cell wall synthesis													biological_process											owl:Class	
GO:0048803	biolink:NamedThing	imaginal disc-derived male genitalia morphogenesis	The process in which the anatomical structures of male genitalia are generated and organized from the genital imaginal disc.	tmpzr1t_l9r_go_relaxed.owl	male genital morphogenesis													biological_process											owl:Class	
GO:0003042	biolink:NamedThing	vasoconstriction of artery involved in carotid body chemoreceptor response to lowering of systemic arterial blood pressure	A process that is triggered by carotid body-vasomotor excitation and results in a decrease in the diameter of an artery during the chemoreceptor response to decreased blood pressure.	tmpzr1t_l9r_go_relaxed.owl	vasoconstriction of artery during carotid body chemoreceptor response to lowering of systemic arterial blood pressure													biological_process											owl:Class	
GO:0060797	biolink:NamedThing	transforming growth factor beta receptor signaling pathway involved in primary germ layer cell fate commitment	A series of molecular signals initiated by the binding of an extracellular ligand to a transforming growth factor beta receptor on the surface of a target cell, which contributes to an unspecified cell adopting a mesoderm fate.	tmpzr1t_l9r_go_relaxed.owl	transforming growth factor beta receptor signalling pathway involved in primary germ layer cell fate commitment							dph	2009-08-04T03:41:44Z					biological_process											owl:Class	
GO:0048921	biolink:NamedThing	posterior lateral line neuromast cupula development	The process whose specific outcome is the progression of the posterior lateral line neuromast cupula over time, from its formation to the mature structure. The cupula is secreted by mantle cells and the ciliary bundles of all of the hair cells of the neuromast are embedded in it. The cupula provides a mechanical linkage between the hair cells and the external hydrodynamic environment. The cupula of superficial neuromasts grows continuously, while the height of the cupula of canal neuromasts is limited by canal diameter.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0072488	biolink:NamedThing	ammonium transmembrane transport	The process in which ammonium is transported across a membrane. Ammonium is the cation NH4+.	tmpzr1t_l9r_go_relaxed.owl	ammonia transport|ammonium membrane transport|ammonium transport	https://github.com/geneontology/go-ontology/issues/22228				Note that this term is not intended for use in annotating lateral movement within membranes.		mah	2010-12-10T10:29:57Z			GO:0015696		biological_process											owl:Class	
GO:0097014	biolink:NamedThing	ciliary plasm	All of the contents of a cilium, excluding the plasma membrane surrounding the cilium.	tmpzr1t_l9r_go_relaxed.owl	cilium cytoplasm|microtubule-based flagellum matrix|ciliary cytoplasm|microtubule-based flagellum cytoplasm|cilium plasm|microtubule-based flagellar matrix|microtubule-based flagellar cytoplasm|cilial cytoplasm					Note that we deem cilium and microtubule-based flagellum to be equivalent. Also, researchers consider the composition of both the plasm and the membrane of the cilium to be detectably different from that in the non-ciliary cytosol and plasma membrane (e.g. in terms of calcium ion concentration, membrane lipid composition, and more). For this reason, the term "ciliary plasm" is not linked to "cytoplasm".		pr	2011-03-23T01:52:31Z					cellular_component											owl:Class	
GO:0140545	biolink:NamedThing	protein disaggregase activity	An ATP-dependent molecular chaperone activity that mediates the solubilization of ordered protein aggregates.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/19173						pg	2020-11-10T16:57:19Z					molecular_function											owl:Class	
GO:0072576	biolink:NamedThing	liver morphogenesis	The process in which the anatomical structures of the liver are generated and organized.	tmpzr1t_l9r_go_relaxed.owl								mah	2011-02-02T03:41:30Z					biological_process											owl:Class	
GO:0030233	biolink:NamedThing	deoxynucleotide transmembrane transporter activity	Catalyzes transport of all four deoxy (d) NDPs, and, less efficiently, the corresponding dNTPs, in exchange for dNDPs, ADP, or ATP.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0000438	biolink:NamedThing	core TFIIH complex portion of holo TFIIH complex	The core TFIIH complex when it is part of the general transcription factor TFIIH.	tmpzr1t_l9r_go_relaxed.owl	SSL2-core TFIIH complex portion of holo TFIIH complex											GO:0000443		cellular_component											owl:Class	
GO:0009853	biolink:NamedThing	photorespiration	A light-dependent catabolic process occurring concomitantly with photosynthesis in plants (especially C3 plants) whereby dioxygen (O2) is consumed and carbon dioxide (CO2) is evolved. The substrate is glycolate formed in large quantities in chloroplasts from 2-phosphoglycolate generated from ribulose 1,5-bisphosphate by the action of ribulose-bisphosphate carboxylase; the glycolate enters the peroxisomes where it is converted by glycolate oxidase to glyoxylate which undergoes transamination to glycine. This then passes into the mitochondria where it is decarboxylated forming one molecule of serine for every two molecules of glycine. This pathway also exists in photosynthetic bacteria.	tmpzr1t_l9r_go_relaxed.owl	photorespiratory pathway				Wikipedia:Photorespiration|MetaCyc:PWY-181									biological_process											owl:Class	
GO:0090389	biolink:NamedThing	phagosome-lysosome fusion involved in apoptotic cell clearance	The creation of a phagolysosome from a phagosome and a lysosome as a part of apoptotic cell clearance.	tmpzr1t_l9r_go_relaxed.owl								tb	2010-10-27T10:57:39Z					biological_process											owl:Class	
GO:0090387	biolink:NamedThing	phagolysosome assembly involved in apoptotic cell clearance	The process in which a phagosome, a vesicle formed by phagocytosis, fuses with a lysosome as a part of apoptotic cell clearance.	tmpzr1t_l9r_go_relaxed.owl								tb	2010-10-27T10:57:39Z					biological_process											owl:Class	
GO:0010730	biolink:NamedThing	negative regulation of hydrogen peroxide biosynthetic process	Any process that decreases the rate, frequency or extent of hydrogen peroxide biosynthesis. The chemical reactions and pathways resulting in the formation of hydrogen peroxide (H2O2), a potentially harmful byproduct of aerobic cellular respiration which can cause damage to DNA.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of hydrogen peroxide biosynthesis													biological_process											owl:Class	
GO:0005831	biolink:NamedThing	steroid hormone aporeceptor complex	A protein complex consisting of a steroid receptor associated with nonreceptor proteins, minimally a dimer of Hsp90 and a monomer of hsp56/FKBP59; forms in the absence of bound ligand.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0061237	biolink:NamedThing	convergent extension involved in mesonephric nephron morphogenesis	The morphogenetic process in which the renal epithelium narrows along one axis and lengthens in a perpendicular axis that contributes to the shaping of a nephron in the mesonephros.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-08-19T03:02:44Z					biological_process											owl:Class	
GO:0010434	biolink:NamedThing	bract formation	The process that gives rise to a bract. This process pertains to the initial formation of a structure from unspecified parts. A bract is a leaf, usually different in form from the foliage leaves, subtending a flower or inflorescence.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0045276	biolink:NamedThing	plasma membrane respiratory chain complex III	A part of the respiratory chain located in the plasma membrane, containing about 10 polypeptide subunits including four redox centers: cytochrome b/b6, cytochrome c1 and an 2Fe-2S cluster. Catalyzes the oxidation of ubiquinol by oxidized cytochrome c1. Examples of this component are found in bacterial species.	tmpzr1t_l9r_go_relaxed.owl	ubiquinol-cytochrome c oxidoreductase complex|respiratory chain complex III|plasma membrane coenzyme Q-cytochrome c reductase complex|plasma membrane ubiquinol-cytochrome-c reductase complex|ubiquinol-cytochrome-c reductase complex|plasma membrane cytochrome bc1 complex|plasma membrane coenzyme Q-cytochrome c oxidoreductase complex											GO:0045286		cellular_component											owl:Class	
GO:0060374	biolink:NamedThing	mast cell differentiation	The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of a mast cell. A mast cell is a cell that is found in almost all tissues containing numerous basophilic granules and capable of releasing large amounts of histamine and heparin upon activation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0010996	biolink:NamedThing	response to auditory stimulus	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an auditory stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to sound|response to sound stimulus							tb	2009-06-10T11:09:38Z					biological_process											owl:Class	
GO:0042890	biolink:NamedThing	3-phenylpropionic acid transmembrane transporter activity	Enables the transfer of 3-phenylpropionic acid from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	hydrocinnamic acid transporter activity|HCA transporter activity|3-phenylpropionate acid transporter activity													molecular_function											owl:Class	
GO:0035472	biolink:NamedThing	choriogonadotropin hormone receptor activity	Combining with the choriogonadotropin hormone to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	chorio-gonadotrophin receptor activity|CG receptor activity|chorionic gonadotropin hormone receptor							bf	2010-04-22T04:49:57Z					molecular_function											owl:Class	
GO:2001090	biolink:NamedThing	maltotriulose transport	The directed movement of a maltotriuloseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl								jl	2011-09-21T01:44:15Z					biological_process											owl:Class	
GO:0006388	biolink:NamedThing	tRNA splicing, via endonucleolytic cleavage and ligation	Splicing of tRNA substrates via recognition of the folded RNA structure that brings the 5' and 3' splice sites into proximity and cleavage of the RNA at both the 3' and 5' splice sites by an endonucleolytic mechanism, followed by ligation of the exons.	tmpzr1t_l9r_go_relaxed.owl	tRNA-Y splicing					Note that while typically associated with tRNA splicing, splicing via endonucleolytic cleavages and subsequent ligation of the free exon ends is known to be used for some non-tRNA substrates, e.g. HAC1 (YFL031W) in S. cerevisiae and an intron in the 23S rRNA of the Archaeal species Desulfurococcus mobilis.								biological_process											owl:Class	
GO:0042588	biolink:NamedThing	zymogen granule	A membrane-bounded, cytoplasmic secretory granule found in enzyme-secreting cells and visible by light microscopy. Contain zymogen, an inactive enzyme precursor, often of a digestive enzyme.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0048773	biolink:NamedThing	erythrophore differentiation	The process in which a relatively unspecialized cell acquires the specialized features of an erythrophore cell. Erythrophores are pigment cells derived from the neural crest. They contain pteridine and/or carotenoid pigments in structures called pterinosomes or erythrosomes. This gives them an orange to red appearance.	tmpzr1t_l9r_go_relaxed.owl	erythrophore cell differentiation													biological_process											owl:Class	
GO:0022038	biolink:NamedThing	corpus callosum development	The process whose specific outcome is the progression of the corpus callosum over time, from its formation to the mature structure. The corpus callosum is a thick bundle of nerve fibers comprising a commissural plate connecting the two cerebral hemispheres. It consists of contralateral axon projections that provide communication between the right and left cerebral hemispheres.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0060722	biolink:NamedThing	cell proliferation involved in embryonic placenta development	The multiplication or reproduction of cells, resulting in the expansion of the population in the embryonic placenta.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-06-12T12:46:04Z					biological_process											owl:Class	
GO:0015768	biolink:NamedThing	maltose transport	The directed movement of maltose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Maltose is the disaccharide 4-O-alpha-D-glucopyranosyl-D-glucopyranose, an intermediate in the catabolism of glycogen and starch.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0000002	biolink:NamedThing	mitochondrial genome maintenance	The maintenance of the structure and integrity of the mitochondrial genome; includes replication and segregation of the mitochondrial chromosome.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0051867	biolink:NamedThing	general adaptation syndrome, behavioral process	The set of behavioral processes that occur as part of the general adaptation syndrome, the response of the body to a strong, stressful stimulus.	tmpzr1t_l9r_go_relaxed.owl	behavioural process during general adaptation syndrome|general adaptation syndrome, behavioral response|general adaptation syndrome, behavioural process|behavioural response during general adaptation syndrome|general adaptation syndrome, behavioural response|behavioral process during general adaptation syndrome|behavioral response during general adaptation syndrome													biological_process											owl:Class	
GO:0010287	biolink:NamedThing	plastoglobule	A lipoprotein particle present in chloroplasts. They are rich in non-polar lipids (triglycerides, esters) as well as in prenylquinones, plastoquinone and tocopherols. Plastoglobules are often associated with thylakoid membranes, suggesting an exchange of lipids with thylakoids.	tmpzr1t_l9r_go_relaxed.owl	PG|plastoglobuli											GO:0010502		cellular_component											owl:Class	
GO:0099560	biolink:NamedThing	synaptic membrane adhesion	The attachment of presynaptic membrane to postsynaptic membrane via adhesion molecules that are at least partially embedded in the plasma membrane.	tmpzr1t_l9r_go_relaxed.owl	synapse adhesion between pre- and post-synapse													biological_process											owl:Class	
GO:0021758	biolink:NamedThing	putamen development	The progression of the putamen over time from its initial formation until its mature state. The putamen is the lens-shaped basal ganglion involved with control of voluntary movement in the brain.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0044294	biolink:NamedThing	dendritic growth cone	The migrating motile tip of a growing nerve cell dendrite.	tmpzr1t_l9r_go_relaxed.owl	dendrite growth cone				NIF_Subcellular:sao1594955670			jl	2010-02-04T03:45:27Z					cellular_component											owl:Class	
GO:0044177	biolink:NamedThing	host cell Golgi apparatus	A compound membranous cytoplasmic organelle of eukaryotic host cells, consisting of flattened, ribosome-free vesicles arranged in a more or less regular stack.	tmpzr1t_l9r_go_relaxed.owl	host Golgi apparatus							jl	2009-09-04T03:14:38Z					cellular_component											owl:Class	
GO:1904756	biolink:NamedThing	negative regulation of gut granule assembly	Any process that stops, prevents or reduces the frequency, rate or extent of gut granule assembly.	tmpzr1t_l9r_go_relaxed.owl	downregulation of gut granule formation|negative regulation of gut granule biogenesis|down regulation of gut granule biogenesis|down regulation of gut granule assembly|downregulation of gut granule biogenesis|inhibition of gut granule biogenesis|down regulation of gut granule formation|down-regulation of gut granule assembly|negative regulation of gut granule formation|down-regulation of gut granule biogenesis|inhibition of gut granule assembly|inhibition of gut granule formation|down-regulation of gut granule formation|downregulation of gut granule assembly							ah	2015-10-21T08:43:51Z					biological_process											owl:Class	
GO:1990071	biolink:NamedThing	TRAPPII protein complex	A complex that mediates intra-Golgi traffic, Golgi exit, endosome-to-Golgi traffic, and the trafficking of autophagy proteins from Golgi to the phagophore assembly site. Binds to a component of the COPI coat. In yeast it includes the following subunits: Bet3 (as homodimer), Bet5, Tca17, Trs20, Trs23, Trs31, Trs33, Trs65, Trs120, Trs130. The whole complex is thought to dimerize with itself.	tmpzr1t_l9r_go_relaxed.owl								bhm	2013-03-28T14:24:08Z					cellular_component											owl:Class	
GO:1900261	biolink:NamedThing	positive regulation of RNA-directed 5'-3' RNA polymerase activity	Any process that activates or increases the frequency, rate or extent of RNA-directed 5'-3' RNA polymerase activity.	tmpzr1t_l9r_go_relaxed.owl	up regulation of RNA synthetase activity|upregulation of RNA-dependent RNA polymerase activity|up regulation of ribonucleic acid-dependent ribonucleic acid polymerase activity|upregulation of PB1 proteins|upregulation of RDRP|positive regulation of PB1 proteins|positive regulation of RNA-dependent RNA polymerase activity|up regulation of RNA-dependent RNA replicase activity|upregulation of transcriptase|activation of nucleoside-triphosphate:RNA nucleotidyltransferase (RNA-directed)|up regulation of RNA-dependent ribonucleate nucleotidyltransferase activity|up-regulation of RNA-dependent ribonucleate nucleotidyltransferase activity|positive regulation of transcriptase|up-regulation of phage f2 replicase|activation of PB2 proteins|up regulation of nucleoside-triphosphate:RNA nucleotidyltransferase (RNA-directed)|up regulation of ribonucleic replicase activity|upregulation of RNA replicase activity|positive regulation of ribonucleic synthetase activity|upregulation of RNA synthetase activity|up regulation of Q-beta replicase activity|activation of transcriptase|upregulation of RNA-dependent ribonucleate nucleotidyltransferase activity|upregulation of 3D polymerase activity|positive regulation of RNA-directed RNA polymerase activity|up regulation of RNA replicase activity|activation of 3D polymerase activity|activation of RNA-directed RNA polymerase activity|positive regulation of ribonucleic acid-dependent ribonucleate nucleotidyltransferase activity|up regulation of RNA-dependent RNA polymerase activity|up regulation of 3D polymerase activity|positive regulation of ribonucleic acid replicase activity|activation of phage f2 replicase|up-regulation of transcriptase|up-regulation of RNA synthetase activity|activation of RNA replicase activity|activation of Q-beta replicase activity|activation of RNA-dependent ribonucleate nucleotidyltransferase activity|activation of polymerase L|upregulation of ribonucleic acid replicase activity|up-regulation of ribonucleic replicase activity|activation of RNA-dependent RNA polymerase activity|up regulation of polymerase L|positive regulation of RNA-dependent ribonucleate nucleotidyltransferase activity|up regulation of RNA nucleotidyltransferase (RNA-directed) activity|positive regulation of polymerase L|up-regulation of RNA-dependent RNA replicase activity|upregulation of ribonucleic acid-dependent ribonucleate nucleotidyltransferase activity|up-regulation of PB1 proteins|upregulation of ribonucleic acid-dependent ribonucleic acid polymerase activity|positive regulation of RNA nucleotidyltransferase (RNA-directed) activity|activation of PB1 proteins|up regulation of PB2 proteins|upregulation of RNA-directed RNA polymerase activity|activation of ribonucleic acid-dependent ribonucleate nucleotidyltransferase activity|upregulation of nucleoside-triphosphate:RNA nucleotidyltransferase (RNA-directed)|positive regulation of RDRP|up regulation of PB1 proteins|upregulation of polymerase L|up-regulation of RNA-dependent RNA polymerase activity|up-regulation of Q-beta replicase activity|up regulation of phage f2 replicase|up-regulation of ribonucleic acid replicase activity|up regulation of transcriptase|upregulation of RNA-dependent RNA replicase activity|activation of RDRP|up-regulation of RDRP|upregulation of PB2 proteins|positive regulation of RNA replicase activity|positive regulation of 3D polymerase activity|activation of RNA synthetase activity|upregulation of phage f2 replicase|positive regulation of phage f2 replicase|up-regulation of RNA-directed RNA polymerase activity|up regulation of ribonucleic acid replicase activity|upregulation of Q-beta replicase activity|activation of ribonucleic replicase activity|up regulation of ribonucleic synthetase activity|activation of RNA nucleotidyltransferase (RNA-directed) activity|activation of ribonucleic acid-dependent ribonucleic acid polymerase activity|up-regulation of RNA nucleotidyltransferase (RNA-directed) activity|upregulation of ribonucleic replicase activity|up-regulation of ribonucleic acid-dependent ribonucleate nucleotidyltransferase activity|positive regulation of ribonucleic acid-dependent ribonucleic acid polymerase activity|up regulation of RNA-directed RNA polymerase activity|up regulation of ribonucleic acid-dependent ribonucleate nucleotidyltransferase activity|upregulation of RNA nucleotidyltransferase (RNA-directed) activity|activation of ribonucleic acid replicase activity|up-regulation of nucleoside-triphosphate:RNA nucleotidyltransferase (RNA-directed)|positive regulation of nucleoside-triphosphate:RNA nucleotidyltransferase (RNA-directed)|up-regulation of polymerase L|activation of RNA-dependent RNA replicase activity|positive regulation of RNA-dependent RNA replicase activity|up-regulation of ribonucleic synthetase activity|positive regulation of RNA synthetase activity|up-regulation of 3D polymerase activity|up-regulation of ribonucleic acid-dependent ribonucleic acid polymerase activity|up-regulation of RNA replicase activity|activation of ribonucleic synthetase activity|upregulation of ribonucleic synthetase activity|up-regulation of PB2 proteins|positive regulation of Q-beta replicase activity|up regulation of RDRP|positive regulation of ribonucleic replicase activity|positive regulation of PB2 proteins							tb	2012-04-03T11:02:11Z					biological_process											owl:Class	
GO:0044823	biolink:NamedThing	retroviral integrase activity	Catalysis of the covalent insertion of double-stranded retroviral DNA into host DNA. Proceeds by an endonucleolytic cleavage at each 3'-OH extremity of the viral genome, named 3'-processing, followed by a strand transfer reaction leading to the insertion of the processed viral DNA into the target DNA by a trans-esterification mechanism.	tmpzr1t_l9r_go_relaxed.owl								jl	2014-02-04T14:09:34Z					molecular_function											owl:Class	
GO:0060036	biolink:NamedThing	notochord cell vacuolation	The assembly and arrangement of a vacuole within a cell of the notochord.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0001018	biolink:NamedThing	mitochondrial promoter sequence-specific DNA binding	Binding to a DNA region that controls the transcription of the mitochondrial DNA.	tmpzr1t_l9r_go_relaxed.owl	mitochondrial RNA polymerase core promoter sequence-specific DNA binding|mitochondrial light strand promoter sense binding|LSPas binding|LSP non-coding strand binding|mitochondrial RNA polymerase regulatory region DNA binding|LSP coding strand binding|HSPs binding|mitochondrial proximal promoter sequence-specific DNA binding|mitochondrial heavy strand promoter anti-sense binding|HSP coding strand binding|LSPs binding|mitochondrial RNA polymerase regulatory region sequence-specific DNA binding|mitochondrial light strand promoter anti-sense binding|HSPas binding|mitochondrial RNA polymerase core promoter proximal region sequence-specific DNA binding|HSP non-coding strand binding|mitochondrial heavy strand promoter sense binding							krc	2010-08-25T04:11:49Z			GO:0070362|GO:0070363|GO:0070361|GO:0001044|GO:0070364|GO:0000997|GO:0001045		molecular_function											owl:Class	
GO:0090248	biolink:NamedThing	cell migration involved in somitogenic axis elongation	Any process involved in the controlled self-propelled movement of a cell that contributes to somitogenic axis elongation.	tmpzr1t_l9r_go_relaxed.owl	cell motility involved in somitogenic axis elongation	https://github.com/geneontology/go-annotation/issues/2040						tb	2010-01-22T11:13:59Z			GO:0090247		biological_process											owl:Class	
GO:0042934	biolink:NamedThing	achromobactin transmembrane transporter activity	Enables the transfer of achromobactin, a citrate siderophore, from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	achromobactin transporter activity													molecular_function											owl:Class	
GO:0031521	biolink:NamedThing	spitzenkorper	Structure within the hyphal tip of filamentous fungi that acts as an organizing center for hyphal tip growth; may function to supply vesicles to the elongating tip and/or to organize cytoskeletal microfilaments.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:1904691	biolink:NamedThing	negative regulation of type B pancreatic cell proliferation	Any process that stops, prevents or reduces the frequency, rate or extent of type B pancreatic cell proliferation.	tmpzr1t_l9r_go_relaxed.owl	downregulation of type B pancreatic cell proliferation|inhibition of type B pancreatic cell proliferation|inhibition of pancreatic beta cell proliferation|down regulation of pancreatic beta cell proliferation|inhibition of pancreatic B cell proliferation|down regulation of pancreatic B cell proliferation|down regulation of type B pancreatic cell proliferation|negative regulation of pancreatic B cell proliferation|negative regulation of pancreatic beta cell proliferation|down-regulation of pancreatic B cell proliferation|downregulation of pancreatic beta cell proliferation|downregulation of pancreatic B cell proliferation|down-regulation of type B pancreatic cell proliferation|down-regulation of pancreatic beta cell proliferation							sl	2015-09-25T15:23:38Z					biological_process											owl:Class	
GO:0044342	biolink:NamedThing	type B pancreatic cell proliferation	The multiplication or reproduction of pancreatic B cells, resulting in the expansion of an pancreatic B cell population. Pancreatic B cell are cells of the pancreas that secrete insulin.	tmpzr1t_l9r_go_relaxed.owl	pancreatic beta cell proliferation|pancreatic B cell proliferation							jl	2010-08-25T01:44:51Z					biological_process											owl:Class	
GO:0021978	biolink:NamedThing	telencephalon regionalization	The regionalization process that creates areas within the forebrain that will direct the behavior of cell migration in differentiation as the telencephalon develops.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0021973	biolink:NamedThing	corticospinal neuron axon decussation	The process in which the migration of an axon growth cone of a pyramidal cell that is part of the corticospinal tract is directed to cross the midline to the contralateral side.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0001112	biolink:NamedThing	DNA-templated transcription open complex formation	Any process involved in the melting of the DNA hybrid of the core promoter region within the transcriptional closed complex of an RNA polymerase preinitiation complex (PIC) to produce an open complex where the DNA duplex around the transcription initiation site is unwound to form the transcription bubble.	tmpzr1t_l9r_go_relaxed.owl	transcriptional open complex formation at bacterial-type RNA polymerase promoter|DNA-dependent transcriptional open complex formation|transcription open complex formation at bacterial-type RNA polymerase promoter|DNA-templated transcriptional open complex formation|promoter melting							krc	2010-12-02T02:15:04Z			GO:0001127		biological_process											owl:Class	
GO:0060503	biolink:NamedThing	bud dilation involved in lung branching	The process in which a bud in the lung increases radially.	tmpzr1t_l9r_go_relaxed.owl	bud expansion													biological_process											owl:Class	
GO:0005631	biolink:NamedThing	chitosan layer of spore wall	The second outermost layer of the spore wall, as described in Saccharomyces.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0070545	biolink:NamedThing	PeBoW complex	A protein complex that is involved in coordinating ribosome biogenesis with cell cycle progression. In human, it is composed of Pes1, Bop1, and WDR12; in Saccharomyces the proteins are known as Nop7p, Erb1 and Ytm1 respectively.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0060672	biolink:NamedThing	epithelial cell morphogenesis involved in placental branching	The change in form (cell shape and size) that occurs when a trophoblast cell elongates to contribute to the branching of the placenta.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-06-02T12:44:52Z					biological_process											owl:Class	
GO:0001072	biolink:NamedThing	transcription antitermination factor activity, RNA binding	Binds to RNA, typically within the nascent RNA transcript, to promote readthrough of a transcription termination site and thus extending the length of the RNA transcript produced. Examples of antitermination factors which bind the nascent RNA include the lambda N protein and the HIV-1 tat protein.	tmpzr1t_l9r_go_relaxed.owl	RNA binding transcription antitermination factor activity							krc	2010-10-21T04:48:17Z					molecular_function											owl:Class	
GO:0021861	biolink:NamedThing	forebrain radial glial cell differentiation	The process in which neuroepithelial cells of the neural tube give rise to radial glial cells, specialized bipotential progenitors cells of the forebrain. Differentiation includes the processes involved in commitment of a cell to a specific fate.	tmpzr1t_l9r_go_relaxed.owl	radial glial cell differentiation in forebrain													biological_process											owl:Class	
GO:0071361	biolink:NamedThing	cellular response to ethanol	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ethanol stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-12-11T03:02:59Z					biological_process											owl:Class	
GO:0035846	biolink:NamedThing	oviduct epithelium development	The progression of the oviduct epithelium over time from its initial formation to the mature structure. An oviduct is a tube through which an ova passes from the ovary to the uterus, or from the ovary to the outside of the organism. The oviduct epithelium is the specialized epithelium that lines the oviduct.	tmpzr1t_l9r_go_relaxed.owl	fallopian tube epithelium development							bf	2011-05-10T10:53:05Z					biological_process											owl:Class	
GO:0086082	biolink:NamedThing	cell adhesive protein binding involved in AV node cell-bundle of His cell communication	Binding to a protein or protein complex that results in the connection of an AV node cell with a bundle of His cell and contributes to the communication between the two cells.	tmpzr1t_l9r_go_relaxed.owl	cell adhesive protein binding involved in atrioventricular node cell-bundle of His cell communication							dph	2011-11-22T11:09:37Z					molecular_function											owl:Class	
GO:0120113	biolink:NamedThing	cytoplasm to vacuole transport by the NVT pathway	A pathway targeting soluble cytosolic proteins to the vacuole lumen. It uses a selective autophagy receptor protein Nbr1, which is an ortholog of mammalian NBR1, and is remotely related to S. cerevisiae Cvt pathway receptor protein Atg19. Similar to the Cvt pathway, the cargos transported by this pathway are hydrolases, which presumably contribute to the hydrolytic activities in the vacuole lumen. Different from the Cvt pathway, this pathway does not require the macroautophagy machinery, but instead relies on the ESCRT machinery for cargo sequestration. This pathway is observed in the fission yeast S. pombe.	tmpzr1t_l9r_go_relaxed.owl	protein localization by the NVT pathway|cytoplasm to vacuole targeting|protein localization by the Nbr1-mediated vacuolar targeting pathway|cytoplasm-to-vacuole targeting							krc	2017-11-03T16:07:55Z					biological_process											owl:Class	
GO:1990758	biolink:NamedThing	mitotic sister chromatid biorientation	The mitotic cell cycle process in which sister chromatids establish stable, end-on attachments to the plus ends of microtubules emanating from opposite spindle poles, oriented such that separation can proceed. This is the final step in metaphase plate congression.	tmpzr1t_l9r_go_relaxed.owl								vw	2015-06-02T12:36:17Z					biological_process											owl:Class	
GO:0002882	biolink:NamedThing	positive regulation of chronic inflammatory response to non-antigenic stimulus	Any process that activates or increases the frequency, rate, or extent of a chronic inflammatory response to a non-antigenic stimulus.	tmpzr1t_l9r_go_relaxed.owl	up regulation of chronic inflammatory response to non-antigenic stimulus|upregulation of chronic inflammatory response to non-antigenic stimulus|stimulation of chronic inflammatory response to non-antigenic stimulus|activation of chronic inflammatory response to non-antigenic stimulus|up-regulation of chronic inflammatory response to non-antigenic stimulus													biological_process											owl:Class	
GO:0002545	biolink:NamedThing	chronic inflammatory response to non-antigenic stimulus	A chronic inflammatory response to a non-antigenic stimulus such as heat or physical trauma.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0004689	biolink:NamedThing	phosphorylase kinase activity	Catalysis of the reaction: 4 ATP + 2 phosphorylase b = 4 ADP + phosphorylase a.	tmpzr1t_l9r_go_relaxed.owl	glycogen phosphorylase kinase activity|phosphorylase kinase, intrinsic catalyst activity|PHK|dephosphophosphorylase kinase activity|phosphorylase kinase (phosphorylating) activity|STK17|ATP:phosphorylase-b phosphotransferase activity|phosphorylase B kinase activity				Reactome:R-HSA-71541|Reactome:R-HSA-71588|MetaCyc:2.7.11.19-RXN|Reactome:R-HSA-453337|EC:2.7.11.19							GO:0008606		molecular_function											owl:Class	
GO:0005459	biolink:NamedThing	UDP-galactose transmembrane transporter activity	Enables the transfer of a UDP-galactose from one side of a membrane to the other. UDP-galactose is a substance composed of galactose in glycosidic linkage with uridine diphosphate.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-5652099|Reactome:R-HSA-735702									molecular_function											owl:Class	
GO:0046935	biolink:NamedThing	1-phosphatidylinositol-3-kinase regulator activity	Modulates the activity of the enzyme 1-phosphatidylinositol-3-kinase activity.	tmpzr1t_l9r_go_relaxed.owl	phosphatidylinositol 3-kinase, class I, regulator activity|1-phosphatidylinositol 3-kinase regulator activity					See also the molecular function term '1-phosphatidylinositol-3-kinase activity ; GO:0016303'.								molecular_function											owl:Class	
GO:0021612	biolink:NamedThing	facial nerve structural organization	The process that contributes to the act of creating the structural organization of the facial nerve. This process pertains to the physical shaping of a rudimentary structure. This sensory and motor nerve supplies the muscles of facial expression and the expression and taste at the anterior two-thirds of the tongue. The principal branches are the superficial opthalmic, buccal, palatine and hyomandibular. The main trunk synapses within pterygopalatine ganglion in the parotid gland and this ganglion then gives of nerve branches which supply the lacrimal gland and the mucous secreting glands of the nasal and oral cavities.	tmpzr1t_l9r_go_relaxed.owl	CN VII structural organization|facial nerve structural organisation													biological_process											owl:Class	
GO:0048298	biolink:NamedThing	positive regulation of isotype switching to IgA isotypes	Any process that activates or increases the frequency, rate or extent of isotype switching to IgA isotypes.	tmpzr1t_l9r_go_relaxed.owl	stimulation of isotype switching to IgA isotypes|positive regulation of isotype switch recombination to IgA isotypes|positive regulation of class switching to IgA isotypes|up-regulation of isotype switching to IgA isotypes|up regulation of isotype switching to IgA isotypes|activation of isotype switching to IgA isotypes|positive regulation of class switch recombination to IgA isotypes|upregulation of isotype switching to IgA isotypes													biological_process											owl:Class	
GO:1990205	biolink:NamedThing	taurine dioxygenase complex	A protein complex capable of catalyzing the conversion of taurine and alpha-ketoglutarate to sulfite, aminoacetaldehyde and succinate under sulfur or cysteine starvation conditions. Its expression is repressed by the presence of sulfate or cysteine. In E. coli it is a homodimer or homotetramer of the protein TauD.	tmpzr1t_l9r_go_relaxed.owl	TauD complex|alpha-ketoglutarate-dependent taurine dioxygenase complex|2-aminoethanesulfonate dioxygenase complex							bhm	2013-10-07T13:03:15Z					cellular_component											owl:Class	
GO:0007478	biolink:NamedThing	leg disc morphogenesis	The process in which the anatomical structures derived from the leg disc are generated and organized. This includes the transformation of a leg imaginal disc from a monolayered epithelium in the larvae of holometabolous insects into recognizable adult structures including the leg, coxa and ventral thoracic pleura.	tmpzr1t_l9r_go_relaxed.owl	leg disc metamorphosis													biological_process											owl:Class	
GO:0072684	biolink:NamedThing	mitochondrial tRNA 3'-trailer cleavage, endonucleolytic	Endonucleolytic cleavage of the 3'-end of the pre-tRNA as part of the process of generating the mature 3'-end of the tRNA in the mitochondrion.	tmpzr1t_l9r_go_relaxed.owl	mitochondrial endonucleolytic tRNA 3'-trailer cleavage|mitochondrial tRNA 3'-end cleavage, endonucleolytic|mitochondrial endonucleolytic tRNA 3'-end cleavage							mah	2011-02-23T01:32:52Z					biological_process											owl:Class	
GO:0004741	biolink:NamedThing	[pyruvate dehydrogenase (lipoamide)] phosphatase activity	Catalysis of the reaction: [pyruvate dehydrogenase (lipoamide)] phosphate + H2O = [pyruvate dehydrogenase (lipoamide)] + phosphate.	tmpzr1t_l9r_go_relaxed.owl	phosphopyruvate dehydrogenase phosphatase activity|pyruvate dehydrogenase (lipoamide)-phosphatase activity|pyruvate dehydrogenase (lipoamide) phosphatase activity|pyruvate dehydrogenase phosphatase activity|pyruvate dehydrogenase (lipoamide)-phosphate phosphohydrolase activity|[pyruvate dehydrogenase (lipoamide)] phosphatase, intrinsic catalyst activity				Reactome:R-HSA-204169|RHEA:12669|EC:3.1.3.43|MetaCyc:3.1.3.43-RXN							GO:0019906		molecular_function											owl:Class	
GO:0044852	biolink:NamedThing	nonrepetitive DNA condensation	The process in which chromatin structure of nonrepetitive regions of DNA is compacted prior to and during mitosis in eukaryotic cells.	tmpzr1t_l9r_go_relaxed.owl	nonrepetitive DNA packaging							jl	2014-07-17T14:13:23Z					biological_process											owl:Class	
GO:0016176	biolink:NamedThing	superoxide-generating NADPH oxidase activator activity	Increases the activity of the enzyme superoxide-generating NADPH oxidase.	tmpzr1t_l9r_go_relaxed.owl	neutrophil cytosol factor 2													molecular_function											owl:Class	
GO:0000448	biolink:NamedThing	cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	Endonucleolytic cleavage within ITS2 between the 5.8S rRNA and the LSU-rRNA of an rRNA molecule originally produced as a tricistronic rRNA transcript that contained the Small SubUnit (SSU) rRNA, the 5.8S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript.	tmpzr1t_l9r_go_relaxed.owl	cleavage in ITS2 of tricistronic rRNA transcript to separate 5.8S and LSU rRNAs (SSU-rRNA, 5.8S rRNA, LSU-rRNA)|cleavage at C2											GO:0000490		biological_process											owl:Class	
GO:0042685	biolink:NamedThing	cardioblast cell fate specification	The process in which a cell becomes capable of differentiating autonomously into a cardioblast cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0090010	biolink:NamedThing	transforming growth factor beta receptor signaling pathway involved in primitive streak formation	A series of molecular signals initiated by the binding of an extracellular ligand to a transforming growth factor beta receptor on the surface of a target cell, which contributes to the formation of the primitive streak.	tmpzr1t_l9r_go_relaxed.owl	TGFbeta signaling pathway involved in primitive streak formation|transforming growth factor beta receptor signalling pathway involved in primitive streak formation							tb	2009-07-29T10:38:40Z					biological_process											owl:Class	
GO:0021682	biolink:NamedThing	nerve maturation	A developmental process, independent of morphogenetic (shape) change, that is required for a nerve to attain its fully functional state.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0006097	biolink:NamedThing	glyoxylate cycle	A modification of the TCA cycle occurring in some plants and microorganisms, in which isocitrate is cleaved to glyoxylate and succinate. Glyoxylate can then react with acetyl-CoA to form malate.	tmpzr1t_l9r_go_relaxed.owl	glyoxylate bypass				MetaCyc:GLYOXYLATE-BYPASS|Wikipedia:Glyoxylate_cycle									biological_process											owl:Class	
GO:1905397	biolink:NamedThing	activated CD8-positive, alpha-beta T cell apoptotic process	Any apoptotic process in an activated CD8-positive, alpha-beta T cell.	tmpzr1t_l9r_go_relaxed.owl	activated CD8-positive, alpha-beta T-lymphocyte apoptotic process|activated CD8-positive, alpha-beta T lymphocyte apoptosis|activated CD8-positive, alpha-beta T cell apoptosis|activated CD8-positive, alpha-beta T-cell apoptotic process|activated CD8-positive, alpha-beta T lymphocyte apoptotic process|activated CD8-positive, alpha-beta T-cell apoptosis|activated CD8-positive, alpha-beta T-lymphocyte apoptosis							pga	2016-08-25T08:09:27Z					biological_process											owl:Class	
GO:0022619	biolink:NamedThing	generative cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a generative cell. The generative cell gives rise to the sperm cells in the male gametophyte.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0032062	biolink:NamedThing	positive regulation of translation in response to osmotic stress	Any process that activates or increases the frequency, rate or extent of translation as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of translation in response to osmotic stress|stimulation of translation in response to osmotic stress|activation of translation in response to osmotic stress|upregulation of translation in response to osmotic stress|up regulation of translation in response to osmotic stress													biological_process											owl:Class	
GO:0072165	biolink:NamedThing	anterior mesonephric tubule development	The progression of the anterior mesonephric tubule over time, from its initial formation to the mature structure. The anterior mesonephric tubule is an epithelial tube that is part of the mesonephros.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-02-26T01:47:26Z					biological_process											owl:Class	
GO:0090029	biolink:NamedThing	negative regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion	Any process that decreases the frequency, rate or extent of pheromone-dependent signal transduction during conjugation with cellular fusion, a signal transduction process resulting in the relay, amplification or dampening of a signal generated in response to pheromone exposure in organisms that undergo conjugation with cellular fusion.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-08-03T10:27:04Z					biological_process											owl:Class	
GO:0005960	biolink:NamedThing	glycine cleavage complex	A protein complex that catalyzes the reversible oxidation of glycine. In E. coli, it has four components: dihydrolipoamide dehydrogenase, glycine dehydrogenase (decarboxylating), lipoyl-GcvH-protein and aminomethyltransferase, also known as L, P, H, and T.	tmpzr1t_l9r_go_relaxed.owl	glycine cleavage system|glycine synthase complex|glycine decarboxylase complex|glycine dehydrogenase (decarboxylating) complex|glycine dehydrogenase complex (decarboxylating)				Wikipedia:Glycine_decarboxylase_complex							GO:0070015|GO:0005961		cellular_component											owl:Class	
GO:0051594	biolink:NamedThing	detection of glucose	The series of events in which a glucose stimulus is received by a cell and converted into a molecular signal.	tmpzr1t_l9r_go_relaxed.owl	glucose sensing|glucose detection|glucose perception													biological_process											owl:Class	
GO:0035913	biolink:NamedThing	ventral aorta morphogenesis	The process in which the anatomical structures of the ventral aorta are generated and organized. The ventral aorta is a blood vessel in a single-pass circulatory system that carries de-oxygenated blood from the heart to the gills. In a single-pass circulatory system blood passes once through the heart to supply the body once.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-06-24T11:24:36Z					biological_process											owl:Class	
GO:0050959	biolink:NamedThing	echolocation	Echolocation is the method used by some animals (e.g. bats, dolphins and some whales) to determine the location of something by measuring the time it takes for an echo to return from it. These animals emit sound waves and listen for the echo, calculating the distance to the object from the time lapse between sound emission and the echo returning.	tmpzr1t_l9r_go_relaxed.owl	biological sonar|perception of environment using reflected sound waves				Wikipedia:Echolocation									biological_process											owl:Class	
GO:0061229	biolink:NamedThing	mesonephric juxtaglomerulus cell development	The process whose specific outcome is the progression of a mesonephric juxtaglomerulus cell over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-08-19T02:34:25Z					biological_process											owl:Class	
GO:0000222	biolink:NamedThing	plasma membrane proton-transporting V-type ATPase, V0 domain	The V0 domain of a proton-transporting V-type ATPase found in the plasma membrane.	tmpzr1t_l9r_go_relaxed.owl	plasma membrane hydrogen ion-transporting ATPase V0 domain													cellular_component											owl:Class	
GO:0034060	biolink:NamedThing	cyanelle stroma	The space enclosed by the double membrane of a cyanelle.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0048133	biolink:NamedThing	male germ-line stem cell asymmetric division	The self-renewing division of a germline stem cell in the male gonad, to produce a daughter stem cell and a daughter germ cell, which will divide to form the male gametes.	tmpzr1t_l9r_go_relaxed.owl	male germ-line stem cell renewal													biological_process											owl:Class	
GO:0003218	biolink:NamedThing	cardiac left ventricle formation	The developmental process pertaining to the initial formation of a left cardiac ventricle from unspecified parts.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-10-13T09:54:33Z					biological_process											owl:Class	
GO:0003214	biolink:NamedThing	cardiac left ventricle morphogenesis	The process in which the left cardiac ventricle is generated and organized.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-10-13T09:50:08Z					biological_process											owl:Class	
GO:0031176	biolink:NamedThing	endo-1,4-beta-xylanase activity	Catalysis of the endohydrolysis of (1->4)-beta-D-xylosidic linkages in xylans.	tmpzr1t_l9r_go_relaxed.owl	beta-xylanase activity|endo-(1,4)-beta-xylanase(1,4)-beta-xylan 4-xylanohydrolase activity|beta-1,4-xylanase activity|xylanase|1,4-beta-D-xylan xylanohydrolase activity|1,4-beta-xylan xylanohydrolase activity|endo-1,4-xylanase activity|endo-1,4-beta-D-xylanase activity|beta-D-xylanase activity|endo-(1->4)-beta-xylanase(1->4)-beta-xylan 4-xylanohydrolase activity|endo-beta-1,4-xylanase activity|beta-1,4-xylan xylanohydrolase activity				MetaCyc:3.2.1.8-RXN|EC:3.2.1.8									molecular_function											owl:Class	
GO:0004751	biolink:NamedThing	ribose-5-phosphate isomerase activity	Catalysis of the reaction: D-ribose 5-phosphate = D-ribulose 5-phosphate.	tmpzr1t_l9r_go_relaxed.owl	ribose 5-phosphate epimerase activity|ribose phosphate isomerase activity|D-ribose-5-phosphate ketol-isomerase activity|phosphopentosisomerase activity|5-phosphoribose isomerase activity|D-ribose 5-phosphate isomerase activity|phosphoriboisomerase activity|D-ribose-5-phosphate aldose-ketose-isomerase activity|phosphopentoseisomerase activity				EC:5.3.1.6|Reactome:R-HSA-71306|MetaCyc:RIB5PISOM-RXN|Reactome:R-HSA-177784|RHEA:14657|KEGG_REACTION:R01056|Reactome:R-HSA-5660015|Reactome:R-HSA-5660013									molecular_function											owl:Class	
GO:1904941	biolink:NamedThing	positive regulation of DNA nucleotidylexotransferase activity	Any process that activates or increases the frequency, rate or extent of DNA nucleotidylexotransferase activity.	tmpzr1t_l9r_go_relaxed.owl	up regulation of terminal deoxynucleotide transferase activity|positive regulation of deoxyribonucleic acid nucleotidyltransferase activity|up-regulation of terminal deoxynucleotidyltransferase activity|activation of terminal transferase activity|up regulation of DNA nucleotidylexotransferase activity|up regulation of deoxyribonucleic nucleotidyltransferase activity|upregulation of deoxyribonucleic nucleotidyltransferase activity|activation of DNA nucleotidylexotransferase activity|positive regulation of TdT|up regulation of deoxyribonucleic acid nucleotidyltransferase activity|upregulation of terminal transferase activity|up regulation of terminal deoxyribonucleotidyltransferase activity|up-regulation of deoxyribonucleic acid nucleotidyltransferase activity|upregulation of terminal deoxyribonucleotidyltransferase activity|up-regulation of addase activity|up regulation of addase activity|upregulation of terminal deoxynucleotidyltransferase activity|upregulation of TdT|up-regulation of terminal transferase activity|positive regulation of terminal transferase activity|up-regulation of terminal deoxyribonucleotidyltransferase activity|up-regulation of deoxyribonucleic nucleotidyltransferase activity|up regulation of terminal transferase activity|upregulation of addase activity|up regulation of terminal addition enzyme activity|upregulation of terminal addition enzyme activity|positive regulation of terminal addition enzyme activity|activation of deoxyribonucleic nucleotidyltransferase activity|activation of TdT|up regulation of terminal deoxynucleotidyltransferase activity|upregulation of terminal deoxynucleotide transferase activity|up-regulation of DNA nucleotidylexotransferase activity|up regulation of deoxynucleotidyl terminal transferase activity|upregulation of deoxynucleotidyl terminal transferase activity|upregulation of DNA nucleotidylexotransferase activity|up-regulation of terminal addition enzyme activity|activation of terminal addition enzyme activity|up regulation of TdT|positive regulation of terminal deoxyribonucleotidyltransferase activity|positive regulation of deoxynucleotidyl terminal transferase activity|activation of nucleoside-triphosphate:DNA deoxynucleotidylexotransferase activity|positive regulation of deoxyribonucleic nucleotidyltransferase activity|activation of terminal deoxyribonucleotidyltransferase activity|activation of deoxynucleotidyl terminal transferase activity|up regulation of nucleoside-triphosphate:DNA deoxynucleotidylexotransferase activity|positive regulation of nucleoside-triphosphate:DNA deoxynucleotidylexotransferase activity|upregulation of deoxyribonucleic acid nucleotidyltransferase activity|up-regulation of nucleoside-triphosphate:DNA deoxynucleotidylexotransferase activity|positive regulation of addase activity|activation of addase activity|positive regulation of terminal deoxynucleotidyltransferase activity|upregulation of nucleoside-triphosphate:DNA deoxynucleotidylexotransferase activity|activation of deoxyribonucleic acid nucleotidyltransferase activity|up-regulation of deoxynucleotidyl terminal transferase activity|up-regulation of terminal deoxynucleotide transferase activity|activation of terminal deoxynucleotidyltransferase activity|activation of terminal deoxynucleotide transferase activity|up-regulation of TdT|positive regulation of terminal deoxynucleotide transferase activity							bc	2016-02-02T15:16:12Z					biological_process											owl:Class	
GO:0007279	biolink:NamedThing	pole cell formation	Formation of a small group of cells (pole cells) at the posterior pole of the insect blastula. They are the first cells to cellularize after the arrival of nuclei at the end of the syncytial blastula stage and are the precursors to the insect germ cells.	tmpzr1t_l9r_go_relaxed.owl						See also the Cell Ontology term 'pole cell ; CL:0000301'.								biological_process											owl:Class	
GO:1904670	biolink:NamedThing	actin filament polymerization involved in mitotic actomyosin contractile ring assembly	Any actin filament polymerization that is involved in mitotic actomyosin contractile ring assembly.	tmpzr1t_l9r_go_relaxed.owl								vw	2015-09-09T20:05:56Z					biological_process											owl:Class	
GO:0098550	biolink:NamedThing	lumenal side of early endosome membrane	The side (leaflet) of the early endosome membrane that faces the lumen.	tmpzr1t_l9r_go_relaxed.owl	internal side of early endosome membrane|internal leaflet of early endosome membrane													cellular_component											owl:Class	
GO:0001110	biolink:NamedThing	promoter clearance from RNA polymerase III promoter	Any process involved in the transition from the initiation to the elongation phases of transcription by RNA polymerase III, generally including a conformational change from the initiation conformation to the elongation conformation. Promoter clearance often involves breaking contact with transcription factors involved only in the initiation phase.	tmpzr1t_l9r_go_relaxed.owl								krc	2010-12-01T03:08:29Z					biological_process											owl:Class	
GO:0036513	biolink:NamedThing	Derlin-1 retrotranslocation complex	A protein complex that functions in the retrotranslocation step of ERAD (ER-associated protein degradation), and includes at its core Derlin-1 oligomers forming a retrotranslocation channel.	tmpzr1t_l9r_go_relaxed.owl	Derlin-1 retrotranslocon|Derlin-1 complex|Derlin-1 retro-translocation complex|Derlin-1 protein dislocation complex|ERAD protein dislocation complex					The Derlin-1 retrotranslocation complex is likely to assemble in steps, thereby containing different components at different stages of the retrotranslocation process.		bf	2015-07-01T10:17:30Z					cellular_component											owl:Class	
GO:1990110	biolink:NamedThing	callus formation	The process by which a callus is formed at a wound site. A plant callus is a portion of plant tissue that consists of mass of undifferentiated plant cells. It consists primarily of parenchyma cells but possibly contains other cell types as the callus begins to differentiate.	tmpzr1t_l9r_go_relaxed.owl								tb	2013-05-29T22:02:52Z					biological_process											owl:Class	
GO:0000015	biolink:NamedThing	phosphopyruvate hydratase complex	A multimeric enzyme complex, usually a dimer or an octamer, that catalyzes the conversion of 2-phospho-D-glycerate to phosphoenolpyruvate and water.	tmpzr1t_l9r_go_relaxed.owl	enolase complex													cellular_component											owl:Class	
GO:0008036	biolink:NamedThing	diuretic hormone receptor activity	Combining with a diuretic hormone and transmitting the signal to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0031928	biolink:NamedThing	pyridoxine transmembrane transporter activity	Enables the transfer of pyridoxine from one side of a membrane to the other. Pyridoxine, 2-methyl-3-hydroxy-4,5-bis(hydroxymethyl)pyridine, is one of the vitamin B6 compounds. Pyridoxal, pyridoxamine and pyridoxine are collectively known as vitamin B6, and are efficiently converted to the biologically active form of vitamin B6, pyridoxal phosphate.	tmpzr1t_l9r_go_relaxed.owl	pyridoxine transporter activity													molecular_function											owl:Class	
GO:1903092	biolink:NamedThing	pyridoxine transmembrane transport	The process in which pyridoxine is transported across a membrane.	tmpzr1t_l9r_go_relaxed.owl								al	2014-06-03T10:41:26Z					biological_process											owl:Class	
GO:0120309	biolink:NamedThing	cilium attachment to cell body	A process that is carried out at the cellular level which results in the lateral attachment of the cilium to the cell body via the flagellar attachment zone in some trypanosomatid species.	tmpzr1t_l9r_go_relaxed.owl	cilial attachment to cell body|ciliary attachment to cell body|flagellar attachment to cell body|flagellum attachment to cell body							krc	2021-03-23T18:01:14Z					biological_process											owl:Class	
GO:0061321	biolink:NamedThing	garland nephrocyte differentiation	The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a garland nephrocyte. A garland nephrocyte is an insect renal cell that filters hemolymph and forms a ring with other garland nephrocytes around the esophagus. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.	tmpzr1t_l9r_go_relaxed.owl	garland cell differentiation							dph	2010-09-24T12:28:16Z			GO:0007514		biological_process											owl:Class	
GO:0003272	biolink:NamedThing	endocardial cushion formation	The developmental process pertaining to the initial formation of an endocardial cushion. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-10-20T08:53:19Z					biological_process											owl:Class	
GO:0044312	biolink:NamedThing	crystalloid	A transient, cytoplasmic organelle found in Plasmodium species that resembles a cytoplasmic inclusion body and whose function is poorly understood. Crystalloids form in ookinetes and disappear after ookinete-to-oocyst transformation.	tmpzr1t_l9r_go_relaxed.owl								jl	2010-02-18T03:58:55Z					cellular_component											owl:Class	
GO:0022622	biolink:NamedThing	root system development	The process whose specific outcome is the progression of the root system over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0001792	biolink:NamedThing	polymeric immunoglobulin receptor activity	Combining with a J-chain-containing polymeric immunoglobulin of the IgA or IgM isotypes via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0001790	biolink:NamedThing	polymeric immunoglobulin binding	Binding to a J-chain-containing polymeric immunoglobulin of the IgA or IgM isotypes.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0016256	biolink:NamedThing	N-glycan processing to lysosome	The modification of high-mannose N-glycans by UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase and the subsequent removal of the N-acetylglucosamine residues yielding mannose-6-P that occurs in the ER-Golgi apparatus to N-glycans destined for the lysosome.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0043951	biolink:NamedThing	negative regulation of cAMP-mediated signaling	Any process which stops, prevents, or reduces the frequency, rate or extent of cAMP-mediated signaling, a series of molecular signals in which a cell uses cyclic AMP to convert an extracellular signal into a response.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of cAMP-mediated signalling													biological_process											owl:Class	
GO:0097555	biolink:NamedThing	right anterior flagellum	A cilium (also called flagellum) found in Giardia species (trophozoite stage). It originates at the right anterior basal body, extends laterally through the cytoplasm, crosses the left anterior axoneme, and exits as a membrane-bound flagellum on the anterior right side of the cell.	tmpzr1t_l9r_go_relaxed.owl	right anterior cilium					Note that we deem cilium and microtubule-based flagellum to be equivalent; the primary term name reflects frequency of use. Also note that, due to the asymmetric nature of the Giardia trophozoite, this term is defined spatially as the trophozoite is viewed from the dorsal side, with the two nuclei dorsal to the ventral disc, and the ventral disc toward the anterior.		pr	2014-02-05T13:18:36Z					cellular_component											owl:Class	
GO:0061032	biolink:NamedThing	visceral serous pericardium development	The progression of the visceral serous pericardium from its formation to the mature structure. The visceral serous pericardium is the inner layer of the pericardium.	tmpzr1t_l9r_go_relaxed.owl	epicardium development							dph	2010-02-09T09:52:49Z					biological_process											owl:Class	
GO:0060039	biolink:NamedThing	pericardium development	The process whose specific outcome is the progression of the pericardium over time, from its formation to the mature structure. The pericardium is a double-walled sac that contains the heart and the roots of the aorta, vena cava and the pulmonary artery.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0031911	biolink:NamedThing	cytoproct	Stable, specialized structure for extrusion of waste by the cell into the surrounding medium.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0000345	biolink:NamedThing	cytosolic DNA-directed RNA polymerase complex	The eubacterial DNA-directed RNA polymerase is a multisubunit complex with a core composed of the essential subunits beta-prime, beta, and two copies of alpha and a fifth nonessential subunit called omega. An additional subunit, a sigma factor, is required for promoter recognition and specificity.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0015795	biolink:NamedThing	sorbitol transport	The directed movement of sorbitol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Sorbitol, also known as glucitol, is the hexitol derived by the reduction of the aldehyde group of glucose.	tmpzr1t_l9r_go_relaxed.owl	glucitol transport													biological_process											owl:Class	
GO:0033344	biolink:NamedThing	cholesterol efflux	The directed movement of cholesterol, cholest-5-en-3-beta-ol, out of a cell or organelle.	tmpzr1t_l9r_go_relaxed.owl	cholesterol export													biological_process											owl:Class	
GO:0072242	biolink:NamedThing	metanephric DCT cell fate commitment	The process in which the developmental fate of a cell becomes restricted such that it will develop into a metanephric distal convoluted tubule cell.	tmpzr1t_l9r_go_relaxed.owl	metanephric distal convoluted tubule cell fate commitment							mah	2010-03-19T03:27:00Z					biological_process											owl:Class	
GO:0071936	biolink:NamedThing	coreceptor activity involved in Wnt signaling pathway	In cooperation with a primary Wnt receptor, initiating a change in cell activity through the Wnt signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	Wnt co-receptor activity|coreceptor activity involved in Wnt receptor signaling pathway|coreceptor activity involved in Wnt-activated signaling pathway|coreceptor activity involved in Wnt receptor signalling pathway							mah	2010-09-30T03:54:34Z					molecular_function											owl:Class	
GO:0101004	biolink:NamedThing	cytolytic granule membrane	The lipid bilayer surrounding the cytolytic granule.	tmpzr1t_l9r_go_relaxed.owl								mec	2015-12-15T04:32:00Z					cellular_component											owl:Class	
GO:0097117	biolink:NamedThing	guanylate kinase-associated protein clustering	The clustering process in which guanylate kinase-associated proteins (GKAPs) are localized to distinct domains in the cell membrane. GKAP facilitates assembly of the post synaptic density of neurons.	tmpzr1t_l9r_go_relaxed.owl	GKAP clustering							pr	2011-07-31T05:44:35Z					biological_process											owl:Class	
GO:0072681	biolink:NamedThing	fibronectin-dependent thymocyte migration	The movement of a thymocyte through distinct intrathymic niches (e.g. medulla, cortex), where it receives a unique set of developmental cues required for T-cell development, dependent on fibronectin in the extracellular matrix.	tmpzr1t_l9r_go_relaxed.owl	fibronectin-dependent immature T-cell migration|fibronectin-dependent immature T-lymphocyte migration|fibronectin-dependent immature T lymphocyte migration|fibronectin-dependent thymic lymphocyte migration|fibronectin-dependent immature T cell migration							mah	2011-02-22T03:53:06Z					biological_process											owl:Class	
GO:0097475	biolink:NamedThing	motor neuron migration	The orderly movement of a motor neuron from one site to another. A motor neuron is an efferent neuron that passes from the central nervous system or a ganglion toward or to a muscle and conducts an impulse that causes movement.	tmpzr1t_l9r_go_relaxed.owl								pr	2013-04-23T13:00:46Z					biological_process											owl:Class	
GO:0051422	biolink:NamedThing	negative regulation of endo-1,4-beta-xylanase activity	Any process that stops or reduces the rate of endo-(1->4)-beta-xylanase activity, the catalysis of the endohydrolysis of (1->4)-beta-D-xylosidic linkages in xylans.	tmpzr1t_l9r_go_relaxed.owl	endo-1,4-beta-xylanase inhibitor|xylanase inhibitor|inhibition of endo-1,4-beta-xylanase activity|down-regulation of endo-1,4-beta-xylanase activity|downregulation of endo-1,4-beta-xylanase activity|down regulation of endo-1,4-beta-xylanase activity													biological_process											owl:Class	
GO:0099576	biolink:NamedThing	regulation of protein catabolic process at postsynapse, modulating synaptic transmission	Any process that modulates synaptic transmission by regulating a catabolic process occurring at a postsynapse.	tmpzr1t_l9r_go_relaxed.owl						Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.								biological_process											owl:Class	
GO:0090594	biolink:NamedThing	inflammatory response to wounding	The immediate defensive reaction by vertebrate tissue to injury caused by chemical or physical agents.	tmpzr1t_l9r_go_relaxed.owl								tb	2014-08-12T12:13:53Z					biological_process											owl:Class	
GO:0048223	biolink:NamedThing	hemicellulose network	Network composed of hemicelluloses; members of a class of plant cell wall polysaccharide that cannot be extracted from the wall by hot water or chelating agents, but can be extracted by aqueous alkali. Includes xylan, glucuronoxylan, arabinoxylan, arabinogalactan II, glucomannan, xyloglucan and galactomannan.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0005055	biolink:NamedThing	laminin receptor activity	Combining with a laminin, a glycoprotein that constitutes the majority of proteins in the basement membrane, to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl						Note that this term represents an activity and not a gene product. Consider also annotating to the molecular function terms 'cell adhesion molecule binding ; GO:0050839' and 'receptor binding ; GO:0005102' and the biological process term 'cell adhesion ; GO:0007155'.								molecular_function											owl:Class	
GO:0072031	biolink:NamedThing	proximal convoluted tubule segment 1 development	The process whose specific outcome is the progression of the S1 portion of the proximal convoluted tubule over time, from its formation to the mature structure. The S1 portion is the initial portion of the proximal convoluted tubule and is responsible for avid reabsorption of water and solutes.	tmpzr1t_l9r_go_relaxed.owl	S1 development							mah	2010-01-25T02:55:57Z					biological_process											owl:Class	
GO:0044190	biolink:NamedThing	host cell mitochondrial envelope	The double lipid bilayer enclosing the host cell mitochondrion and separating its contents from the host cell cytoplasm; includes the intermembrane space.	tmpzr1t_l9r_go_relaxed.owl								jl	2009-10-15T04:12:55Z					cellular_component											owl:Class	
GO:0060460	biolink:NamedThing	left lung morphogenesis	The process in which anatomical structures of the left lung are generated and organized.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0098506	biolink:NamedThing	polynucleotide 3' dephosphorylation	The process of removing one or more phosphate groups from the 3' end of a polynucleotide.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0061057	biolink:NamedThing	peptidoglycan recognition protein signaling pathway	A series of molecular signals initiated by binding of peptidoglycan to a receptor and ending with regulation of a downstream cellular process. The main outcome of the Imd signaling is the production of antimicrobial peptides.	tmpzr1t_l9r_go_relaxed.owl	PGRP signaling pathway|Imd signaling pathway|Imd signalling pathway|immune deficiency signaling pathway|immune deficiency pathway							dph	2010-03-02T12:20:10Z					biological_process											owl:Class	
GO:0051316	biolink:NamedThing	attachment of spindle microtubules to kinetochore involved in meiotic chromosome segregation	The cell cycle process in which spindle microtubules become physically associated with the proteins making up the kinetochore complex contributing to meiotic chromosome segregation.	tmpzr1t_l9r_go_relaxed.owl	attachment of spindle microtubules to kinetochore during meiosis|attachment of spindle microtubules to meiotic chromosome|attachment of spindle microtubules to kinetochore during meiotic chromosome segregation											GO:0051317		biological_process											owl:Class	
GO:0031517	biolink:NamedThing	red light photoreceptor activity	The function of absorbing and responding to electromagnetic radiation with a wavelength of approximately 660nm. The response may involve a change in conformation.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0086095	biolink:NamedThing	positive regulation of IKACh channel activity by G protein-coupled acetylcholine receptor signaling pathway involved in negative regulation of heart rate	A G protein-coupled acetylcholine receptor signaling pathway that contributes to a decrease in frequency or rate of heart contraction through activation of the IKACh potassium channel. Binding of acetylcholine to a G protein-coupled acetylcholine receptor (muscarinic receptor) on the surface of the signal-receiving cell results in liberation of the G-beta/gamma complex from the alpha subunit. The G-beta/gamma complex binds directly to the inward-rectifying potassium channel IKACh. Once the ion channel is activated, potassium ions (K+) flow out of the cell and cause it to hyperpolarize. In its hyperpolarized state, action potentials cannot be fired as quickly as possible, which slows the heart rate.	tmpzr1t_l9r_go_relaxed.owl	muscarinic receptor signaling pathway involved in activation of IKACH|cardiac muscarinic receptor signaling via Gbeta/gamma|muscarinic receptor signaling pathway involved in ion channel activation|Gbeta/gamma-coupled muscarinic receptor signaling pathway involved in negative regulation of heart rate|positive regulation of IKACh channel activity by G-protein coupled acetylcholine receptor signaling							bf						biological_process											owl:Class	
GO:1904406	biolink:NamedThing	negative regulation of nitric oxide metabolic process	Any process that stops, prevents or reduces the frequency, rate or extent of nitric oxide metabolic process.	tmpzr1t_l9r_go_relaxed.owl	down regulation of nitric oxide metabolism|down-regulation of nitric oxide metabolic process|downregulation of nitric oxide metabolism|downregulation of nitric oxide metabolic process|down regulation of nitric oxide metabolic process|negative regulation of nitric oxide metabolism|inhibition of nitric oxide metabolism|inhibition of nitric oxide metabolic process|down-regulation of nitric oxide metabolism							sl	2015-06-24T20:56:41Z					biological_process											owl:Class	
GO:0090636	biolink:NamedThing	outer dense plaque of desmosome	The desmosomal part containing plakoglobins, plakophilins, the N-termini of desmoplakins,  as well as the cytoplasmic tails of the desmosomal cadherins, which together attach the plaque to the plasma membrane.	tmpzr1t_l9r_go_relaxed.owl								tb	2015-04-20T16:10:51Z					cellular_component											owl:Class	
GO:0034274	biolink:NamedThing	Atg12-Atg5-Atg16 complex	A protein complex required for the expansion of the autophagosomal membrane. In budding yeast, this complex consists of Atg12p, Atg5p and Atg16p.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0035209	biolink:NamedThing	pupal development	The process whose specific outcome is the progression of the pupa over time, from its formation to the mature structure. The pupa is a dormant life stage interposed between the larval and the adult stages in insects that undergo a complete metamorphosis.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1904652	biolink:NamedThing	protein localization to cell division site involved in cell separation after cytokinesis	Any protein localization to cell division site that is involved in cell separation after cytokinesis.	tmpzr1t_l9r_go_relaxed.owl								vw	2015-09-01T21:04:45Z					biological_process											owl:Class	
GO:0071697	biolink:NamedThing	ectodermal placode morphogenesis	The process in which the anatomical structures of an ectodermal placode are generated and organized. An ectodermal placode is a thickening of the ectoderm that is the primordium of many structures derived from the ectoderm.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-03-02T11:49:51Z					biological_process											owl:Class	
GO:0046540	biolink:NamedThing	U4/U6 x U5 tri-snRNP complex	A ribonucleoprotein complex that is formed by the association of the U4/U6 and U5 snRNPs.	tmpzr1t_l9r_go_relaxed.owl	U4/U6.U5 snRNP complex													cellular_component											owl:Class	
GO:1905438	biolink:NamedThing	non-canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation	Any non-canonical Wnt signaling pathway that is involved in midbrain dopaminergic neuron differentiation.	tmpzr1t_l9r_go_relaxed.owl	beta-catenin-independent Wnt receptor signaling pathway involved in midbrain dopaminergic neuron production|beta-catenin-independent Wnt receptor signaling pathway involved in DA neurogenesis from midbrain floor plate|beta-catenin-independent Wnt receptor signaling pathway involved in midbrain dopaminergic neuron differentiation|non-canonical Wnt receptor signalling pathway involved in midbrain dopaminergic neuron production|non-canonical Wnt receptor signalling pathway involved in DA neurogenesis from midbrain floor plate|non-canonical Wnt-activated signaling pathway involved in DA neurogenesis from midbrain floor plate|non-canonical Wnt-activated signaling pathway involved in midbrain dopaminergic neuron production|non-canonical Wnt signaling pathway involved in DA neurogenesis from midbrain floor plate|non-canonical Wnt receptor signaling pathway involved in midbrain dopaminergic neuron production|non-canonical Wnt-activated signaling pathway involved in mDA neuron differentiation|non-canonical Wnt signaling pathway involved in midbrain DA neurogenesis|non-canonical Wnt-activated signaling pathway involved in midbrain DA neurogenesis|non-canonical Wnt-activated signaling pathway involved in midbrain dopaminergic neuron differentiation|non-canonical Wnt receptor signaling pathway involved in mDA neuron differentiation|non-canonical Wnt receptor signalling pathway involved in mDA neuron differentiation|non-canonical Wnt receptor signalling pathway involved in midbrain dopaminergic neuron differentiation|non-canonical Wnt receptor signalling pathway involved in midbrain DA neurogenesis|non-canonical Wnt receptor signaling pathway involved in midbrain dopaminergic neuron differentiation|non-canonical Wnt receptor signaling pathway involved in midbrain DA neurogenesis|beta-catenin-independent Wnt receptor signaling pathway involved in midbrain DA neurogenesis|beta-catenin-independent Wnt receptor signaling pathway involved in mDA neuron differentiation|non-canonical Wnt signaling pathway involved in midbrain dopaminergic neuron production|non-canonical Wnt signaling pathway involved in mDA neuron differentiation|non-canonical Wnt receptor signaling pathway involved in DA neurogenesis from midbrain floor plate							bc	2016-09-14T15:52:22Z					biological_process											owl:Class	
GO:0007305	biolink:NamedThing	vitelline membrane formation involved in chorion-containing eggshell formation	Construction of the vitelline membrane portion of a chorion-containing eggshell. An example of this is found in Drosophila melanogaster.	tmpzr1t_l9r_go_relaxed.owl	vitelline membrane formation in chorion-containing eggshell													biological_process											owl:Class	
GO:0007426	biolink:NamedThing	tracheal outgrowth, open tracheal system	The projection of branches of an open tracheal system towards their target tissues. An example of this is found in Drosophila melanogaster.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1904466	biolink:NamedThing	positive regulation of matrix metallopeptidase secretion	Any process that activates or increases the frequency, rate or extent of matrix metallopeptidase secretion.	tmpzr1t_l9r_go_relaxed.owl	activation of MMP secretion|up-regulation of MMP secretion|upregulation of matrix metalloproteinase secretion|activation of matrix metalloproteinase secretion|up-regulation of matrix metalloproteinase secretion|up-regulation of matrix metallopeptidase secretion|upregulation of matrix metallopeptidase secretion|up regulation of matrix metallopeptidase secretion|positive regulation of matrix metalloproteinase secretion|up regulation of MMP secretion|upregulation of MMP secretion|activation of matrix metallopeptidase secretion|up regulation of matrix metalloproteinase secretion|positive regulation of MMP secretion							sl	2015-07-09T19:46:30Z					biological_process											owl:Class	
GO:0060961	biolink:NamedThing	phospholipase D inhibitor activity	Binds to and stops, prevents or reduces the activity of phospholipase D.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-10-05T02:47:26Z					molecular_function											owl:Class	
GO:0060941	biolink:NamedThing	epicardium-derived cardiac fibroblast cell fate commitment	The commitment of an epicardial cell to a cardiac fibroblast cell fate and its capacity to differentiate into a cardiac fibroblast. A cardiac fibroblast is a connective tissue cell in the heart which secretes an extracellular matrix rich in collagen and other macromolecules.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-09-29T01:44:36Z					biological_process											owl:Class	
GO:0030229	biolink:NamedThing	very-low-density lipoprotein particle receptor activity	Combining with a very-low-density lipoprotein particle and delivering the very-low-density lipoprotein into the cell via endocytosis.	tmpzr1t_l9r_go_relaxed.owl	apolipoprotein E receptor activity|VLDL receptor|very-low-density lipoprotein receptor activity				Wikipedia:VLDL_receptor									molecular_function											owl:Class	
GO:0120203	biolink:NamedThing	rod photoreceptor disc lumen	The volume enclosed by the membrane of a rod photoreceptor cell disc membrane.	tmpzr1t_l9r_go_relaxed.owl								krc	2019-05-07T23:49:50Z					cellular_component											owl:Class	
GO:0120200	biolink:NamedThing	rod photoreceptor outer segment	The outer segment of a vertebrate rod photoreceptor that contains sealed membrane discs that are not connected to the ciliary membrane and containing rhodopsin photoreceptor proteins.	tmpzr1t_l9r_go_relaxed.owl								krc	2019-05-07T22:47:20Z					cellular_component											owl:Class	
GO:0039006	biolink:NamedThing	pronephric nephron tubule formation	The developmental process pertaining to the initial formation of a pronephric nephron tubule from unspecified parts. A pronephric nephron tubule is an epithelial tube that is part of a nephron in the pronephros.	tmpzr1t_l9r_go_relaxed.owl	pronephric tubule formation|pronephros tubule formation							bf	2010-07-02T09:37:27Z					biological_process											owl:Class	
GO:0004984	biolink:NamedThing	olfactory receptor activity	Combining with an odorant and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity in response to detection of smell.	tmpzr1t_l9r_go_relaxed.owl	odorant receptor activity													molecular_function											owl:Class	
GO:0098652	biolink:NamedThing	collagen type VII anchoring fibril	An antiparallel dimer of two collagen VII trimers, one end of which is embedded in the lamina densa while the other end attaches to banded collagen fibrils in the dermis.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:1904866	biolink:NamedThing	ventral tegmental area development	The process whose specific outcome is the progression of a ventral tegmental area (VTA) over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl	area tegmentalis ventralis development|ventral tegmental area (Tsai) development|a10a development|ventral tegmental nucleus of tsai development|ventral tegmentum development|ventral brain stem development|ventral tegmental area of tsai development|ventral tegmental nucleus (tsai) development|ventromedial mesencephalic tegmentum development|tegmentum ventrale development|VTA development|area tegmentalis ventralis (Tsai) development|ventral tegmental nucleus (Rioch) development							bf	2015-12-17T14:44:18Z					biological_process											owl:Class	
GO:0140247	biolink:NamedThing	protein catabolic process at presynapse	The chemical reactions and pathways resulting in the breakdown of a protein at a presynapse.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/synapse/issues/204				Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.		pg	2018-07-15T10:23:49Z					biological_process											owl:Class	
GO:0060054	biolink:NamedThing	positive regulation of epithelial cell proliferation involved in wound healing	Any process that activates or increases the rate or extent of epithelial cell proliferation, contributing to the restoration of integrity to a damaged tissue following an injury.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0007477	biolink:NamedThing	notum development	The process whose specific outcome is the progression of the dorsal part of the body over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0035996	biolink:NamedThing	rhabdomere microvillus	Thin cylindrical membrane-covered projection on the surface of a rhabdomere.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-09-01T02:18:30Z					cellular_component											owl:Class	
GO:0090009	biolink:NamedThing	primitive streak formation	The developmental process pertaining to the initial formation of the primitive streak from unspecified parts. The primitive streak is a ridge of cells running along the midline of the embryo where the mesoderm ingresses. It defines the anterior-posterior axis.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-07-29T10:31:31Z					biological_process											owl:Class	
GO:0075201	biolink:NamedThing	penetration hypha formation	The assembly by the symbiont of a threadlike, tubular structure, which may contain multiple nuclei and may or may not be divided internally by septa or cross-walls, for the purpose of penetration into its host organism. In the case of an appressorium existing, this term is defined in further details as the process in which the symbiont penetration peg expands to form a hypha which traverses the epidermal cell and emerges into the intercellular space of the mesophyll tissue. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	formation of symbiont penetration hypha for entry into host|symbiont penetration hypha formation for entry into host	https://github.com/geneontology/go-ontology/issues/18557				Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products from the symbiont involved in this process.								biological_process											owl:Class	
GO:0030478	biolink:NamedThing	actin cap	Polarized accumulation of cytoskeletal proteins (including F-actin) and regulatory proteins in a cell. An example of this is the actin cap found in Saccharomyces cerevisiae.	tmpzr1t_l9r_go_relaxed.owl												GO:0000143		cellular_component											owl:Class	
GO:0005896	biolink:NamedThing	interleukin-6 receptor complex	A hexameric protein complex consisting of two molecules each of interleukin-6, interleukin-6 receptor alpha chain, and gp-130.	tmpzr1t_l9r_go_relaxed.owl	IL-6 receptor complex													cellular_component											owl:Class	
GO:0034441	biolink:NamedThing	plasma lipoprotein particle oxidation	The modification of a lipid or protein within a plasma lipoprotein particle by oxidation of the lipid or one or more amino acids.	tmpzr1t_l9r_go_relaxed.owl	plasma lipoprotein oxidation													biological_process											owl:Class	
GO:0010659	biolink:NamedThing	cardiac muscle cell apoptotic process	A form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases, whose actions dismantle a cardiac muscle cell and result in its death. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction.	tmpzr1t_l9r_go_relaxed.owl	cardiac muscle cell apoptosis													biological_process											owl:Class	
GO:1900029	biolink:NamedThing	positive regulation of ruffle assembly	Any process that activates or increases the frequency, rate or extent of ruffle assembly.	tmpzr1t_l9r_go_relaxed.owl	up regulation of ruffle assembly|positive regulation of membrane ruffle formation|positive regulation of membrane ruffling|up regulation of membrane ruffle formation|up regulation of membrane ruffling							yaf	2012-01-12T05:00:56Z					biological_process											owl:Class	
GO:0051755	biolink:NamedThing	meiotic sister chromatid arm separation	The cell cycle process in which sister chromatid arms are physically detached from each other during meiosis.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0039705	biolink:NamedThing	viral translational readthrough	The continuation of translation of a viral mRNA beyond a stop codon by the use of a special tRNA that recognizes the UAG and UGA codons as modified amino acids, rather than as termination codons.	tmpzr1t_l9r_go_relaxed.owl	viral RNA suppression of termination|viral stop codon readthrough				VZ:859	This term is intended to annotate gene products involved in the process of viral translational readthrough, not viral proteins produced by this translation process.		bf	2013-11-25T13:20:37Z					biological_process											owl:Class	
GO:0052607	biolink:NamedThing	7-hydroxy-chlorophyllide a oxygenase activity	Catalysis of the reaction: 7-hydroxychlorophyllide a + NADPH + O2 + H+ = chlorophyllide b + NADP+ + 2 H2O.	tmpzr1t_l9r_go_relaxed.owl	CAO activity|7-hydroxychlorophyllide-a oxygenase activity|7-hydroxychlorophyllide a:oxygen 7-oxidoreductase activity|chlorophyll b synthetase activity|chlorophyll-b synthase activity				RHEA:22136|MetaCyc:RXN-7677|KEGG_REACTION:R08204									molecular_function											owl:Class	
GO:0140053	biolink:NamedThing	mitochondrial gene expression	The process in which a mitochondrial gene's sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.	tmpzr1t_l9r_go_relaxed.owl								pg	2017-06-26T10:57:45Z					biological_process											owl:Class	
GO:0016338	biolink:NamedThing	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules	The attachment of one cell to another cell via adhesion molecules that do not require the presence of calcium for the interaction.	tmpzr1t_l9r_go_relaxed.owl	calcium-independent cell adhesion molecule activity													biological_process											owl:Class	
GO:0098639	biolink:NamedThing	collagen binding involved in cell-matrix adhesion	Any collagen binding that occurs as part of cell-matrix adhesion.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0120102	biolink:NamedThing	bacterial-type flagellum secretion apparatus	A part of the bacterial-type flagellum that is located at the cytoplasmic side of the MS ring and composed of six membrane proteins (FlhA, FlhB, FliP, FliQ, FliR, and FliO, or orthologs thereof) and three soluble proteins (FliI, FliH, and FliJ, or orthologs thereof) in the cytoplasm. It is responsible for secretion of flagellar type III protein substrates, including the proteins of the flagellar rod, hook, and filament.	tmpzr1t_l9r_go_relaxed.owl	bacterial-type flagellum export apparatus							krc	2017-10-03T16:13:24Z					cellular_component											owl:Class	
GO:0043593	biolink:NamedThing	endospore coat	The layer in a bacterial endospore that lies under the exosporium, and is impermeable to many toxic molecules. The coat may also contain enzymes that are involved in endospore germination.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0001795	biolink:NamedThing	type IIb hypersensitivity	An inflammatory response resulting in cell death or dysfunction mediated by the direct binding of antibody to cellular receptors.	tmpzr1t_l9r_go_relaxed.owl	type V hypersensitivity					Note that some type IIa hypersensitivity response (GO:0001794) are referred to simply as type II hypersensitivity in the earlier literature, but are mechanistically distinct from type IIb hypersensitivity.								biological_process											owl:Class	
GO:1990095	biolink:NamedThing	positive regulation of transcription from RNA polymerase II promoter in response to reactive oxygen species	Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a reactive oxygen species stimulus. Reactive oxygen species include singlet oxygen, superoxide, and oxygen free radicals.	tmpzr1t_l9r_go_relaxed.owl								pr	2013-05-07T12:10:32Z					biological_process											owl:Class	
GO:0021850	biolink:NamedThing	subpallium glioblast cell division	The division of glioblasts in the subpallium. These cells will give rise to oligodendrocytes.	tmpzr1t_l9r_go_relaxed.owl	glioblast division in ventral telencephalon|glioblast cell division in subpallium													biological_process											owl:Class	
GO:0070488	biolink:NamedThing	neutrophil aggregation	The adhesion of one neutrophil to one or more other neutrophils via adhesion molecules.	tmpzr1t_l9r_go_relaxed.owl	neutrocyte aggregation|neutrophilic leukocyte aggregation|neutrophilic leucocyte aggregation|neutrophil leucocyte aggregation|neutrophil leukocyte aggregation													biological_process											owl:Class	
GO:1902736	biolink:NamedThing	positive regulation of receptor-mediated virion attachment to host cell	Any process that activates or increases the frequency, rate or extent of receptor-mediated virion attachment to host cell.	tmpzr1t_l9r_go_relaxed.owl	activation of virion attachment, binding of host cell surface receptor|up-regulation of receptor-mediated virion attachment to host cell|activation of receptor-mediated virion attachment to host cell|up regulation of virion attachment, binding of host cell surface receptor|up regulation of receptor-mediated virion attachment to host cell|positive regulation of virion attachment, binding of host cell surface receptor|upregulation of virion attachment, binding of host cell surface receptor|upregulation of receptor-mediated virion attachment to host cell|up-regulation of virion attachment, binding of host cell surface receptor							als	2014-02-25T12:26:16Z					biological_process											owl:Class	
GO:0044581	biolink:NamedThing	butyryl-CoA catabolic process to butyrate	The chemical reactions a resulting in the resulting in the breakdown of butyryl-CoA to form butyrate.	tmpzr1t_l9r_go_relaxed.owl	butyryl-CoA catabolism to butyrate							jl	2012-04-19T04:29:40Z					biological_process											owl:Class	
GO:1990101	biolink:NamedThing	DnaA-oriC complex	A protein-DNA complex containing the initiator protein DnaA bound to high-affinity recognition sites in the unique origin of replication, oriC. DnaA-oriC binding is the first step in assembly of a bacterial pre-replicative complex (pre-RC) and is responsible for the timely initiation of replication once per cell cycle.	tmpzr1t_l9r_go_relaxed.owl	DnaA-DNA complex							bhm	2013-05-14T12:07:04Z					cellular_component											owl:Class	
GO:0060437	biolink:NamedThing	lung growth	The increase in size or mass of a lung. In all air-breathing vertebrates the lungs are developed from the ventral wall of the oesophagus as a pouch which divides into two sacs. In amphibians and many reptiles the lungs retain very nearly this primitive sac-like character, but in the higher forms the connection with the esophagus becomes elongated into the windpipe and the inner walls of the sacs become more and more divided, until, in the mammals, the air spaces become minutely divided into tubes ending in small air cells, in the walls of which the blood circulates in a fine network of capillaries. In mammals the lungs are more or less divided into lobes, and each lung occupies a separate cavity in the thorax.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1990728	biolink:NamedThing	mitotic spindle assembly checkpoint MAD1-MAD2 complex	A protein complex involved in the assembly of the mitotic checkpoint complex that in turn inhibits the anaphase promoting complex/cyclosome (APC/C). The MAD1 dimer recruits the open form of MAD2 (O-MAD2) turning it into the closed form (C-MAD2) upon binding. C-MAD2 inhibits CDC20, a member of the APC/C, upon release from the MAD1-MAD2 complex.	tmpzr1t_l9r_go_relaxed.owl	MAD1-MAD2 complex					An example of this is MAD1 in human (Q9Y6D9) in PMID:12006501 (inferred from physical interaction).		bhm	2015-04-15T10:14:17Z					cellular_component											owl:Class	
GO:0015771	biolink:NamedThing	trehalose transport	The directed movement of trehalose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Trehalose is a disaccharide isomeric with sucrose and obtained from certain lichens and fungi.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0021919	biolink:NamedThing	BMP signaling pathway involved in spinal cord dorsal/ventral patterning	A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, which contributes to the spatial identity of regions along the dorsal-ventral axis of the spinal cord.	tmpzr1t_l9r_go_relaxed.owl	BMP signalling pathway involved in spinal cord dorsal-ventral patterning|bone morphogenetic protein signalling pathway involved in spinal cord dorsal-ventral patterning|BMP signaling pathway involved in spinal cord dorsal-ventral patterning|bone morphogenetic protein signaling pathway in spinal cord dorsal-ventral patterning|BMP signaling pathway in spinal cord dorsoventral patterning													biological_process											owl:Class	
GO:0048381	biolink:NamedThing	lateral mesoderm structural organization	The process that contributes to the act of creating the structural organization of the lateral mesoderm. This process pertains to the physical shaping of a rudimentary structure.	tmpzr1t_l9r_go_relaxed.owl	lateral mesoderm structural organisation|lateral plate mesoderm structural organization													biological_process											owl:Class	
GO:0061195	biolink:NamedThing	taste bud formation	The developmental process pertaining to the initial formation of the taste bud from unspecified parts. The taste bud is a specialized area of the tongue that contains taste receptors.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-07-27T12:22:26Z					biological_process											owl:Class	
GO:0060709	biolink:NamedThing	glycogen cell differentiation involved in embryonic placenta development	The process in which a relatively unspecialized cell acquires specialized features of a glycogen cell of the placenta. A glycogen cell is a vacuolated glycogen-rich cell that appears in compact cell islets of the spongiotrophoblast layer.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-06-09T10:41:08Z					biological_process											owl:Class	
GO:2000032	biolink:NamedThing	regulation of secondary shoot formation	Any process that modulates the frequency, rate or extent of secondary shoot formation.	tmpzr1t_l9r_go_relaxed.owl	regulation of axillary shoot system formation|regulation of axillary shoot formation|regulation of shoot branching|regulation of auxiliary shoot formation							tb	2010-08-05T11:32:50Z					biological_process											owl:Class	
GO:0120150	biolink:NamedThing	regulation of mitotic actomyosin contractile ring disassembly	Any process that modulates the frequency, rate or extent of mitotic actomyosin contractile ring disassembly.	tmpzr1t_l9r_go_relaxed.owl	regulation of mitotic CAR disassembly|regulation of mitotic actomyosin ring disassembly|regulation of mitotic cytokinetic ring disassembly|regulation of mitotic contractile actomyosin ring disassembly|regulation of mitotic constriction ring disassembly							krc	2018-04-24T15:06:28Z					biological_process											owl:Class	
GO:1990920	biolink:NamedThing	proteasome localization to nuclear periphery	Any process in which the proteasome is transported to, or maintained at the nuclear periphery.	tmpzr1t_l9r_go_relaxed.owl								vw	2015-12-14T17:14:00Z					biological_process											owl:Class	
GO:0048142	biolink:NamedThing	germarium-derived cystoblast division	The four rounds of incomplete mitosis undergone by a cystoblast to form a 16-cell cyst of interconnected cells within a germarium. Within the cyst, one cell differentiates into an oocyte while the rest become nurse cells. An example of this process is found in Drosophila melanogaster.	tmpzr1t_l9r_go_relaxed.owl	germarium-derived cystoblast cell division													biological_process											owl:Class	
GO:0030727	biolink:NamedThing	germarium-derived female germ-line cyst formation	Formation, in a germarium, of a group of interconnected cells derived from a single female gonial founder cell (a cystoblast). The germarium is the most anterior portion of an insect ovariole. An example of this process is found in Drosophila melanogaster.	tmpzr1t_l9r_go_relaxed.owl	germarium-derived female germline cyst formation													biological_process											owl:Class	
GO:0035289	biolink:NamedThing	posterior head segmentation	Partitioning the posterior region of the insect head anlage into gnathal (mandibular, maxillary and labial) segments. Unlike the anterior head (procephalic) segments, formation of the posterior head (gnathal) segments occurs by a similar mechanism to trunk segmentation, where a cascade of gap genes, pair-rule genes and segment-polarity genes subdivide the embryo into progressively smaller domains.	tmpzr1t_l9r_go_relaxed.owl	gnathal segmentation					See also the fly_anatomy.ontology term 'gnathal segment ; FBbt:00000011' and its children.								biological_process											owl:Class	
GO:0048596	biolink:NamedThing	embryonic camera-type eye morphogenesis	The process in which the anatomical structures of the eye are generated and organized during embryonic development.	tmpzr1t_l9r_go_relaxed.owl	embryonic eye morphogenesis													biological_process											owl:Class	
GO:1905528	biolink:NamedThing	positive regulation of Golgi lumen acidification	Any process that activates or increases the frequency, rate or extent of Golgi lumen acidification.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of Golgi lumen acidification|activation of Golgi lumen acidification|up regulation of Golgi lumen acidification|upregulation of Golgi lumen acidification							dph	2016-10-05T13:16:41Z					biological_process											owl:Class	
GO:0038186	biolink:NamedThing	lithocholic acid receptor activity	Combining with lithocholic acid and transmitting the signal to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	LCA receptor activity							bf	2013-05-16T11:13:38Z					molecular_function											owl:Class	
GO:0071644	biolink:NamedThing	negative regulation of chemokine (C-C motif) ligand 4 production	Any process that stops, prevents, or reduces the frequency, rate, or extent of production of chemokine (C-C motif) ligand 4.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of macrophage inflammatory protein production|negative regulation of MIP-1b production|negative regulation of CCL4 production							mah	2010-02-12T10:40:19Z					biological_process											owl:Class	
GO:0010007	biolink:NamedThing	magnesium chelatase complex	A heterotrimeric enzyme complex composed of three subunits, all of which are required for enzyme activity, which catalyzes the chelation of Mg by proto IX in an ATP-dependent manner.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:1990394	biolink:NamedThing	cellular response to cell wall damage	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of cell wall damage. The process begins with detection of the damage and ends with a change in state or activity of the cell.	tmpzr1t_l9r_go_relaxed.owl								al	2014-06-05T16:45:33Z					biological_process											owl:Class	
GO:0071433	biolink:NamedThing	cell wall repair	A process of cell wall organization that results in the restoration of the cell wall following damage.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-12-16T11:00:50Z					biological_process											owl:Class	
GO:0150037	biolink:NamedThing	regulation of calcium-dependent activation of synaptic vesicle fusion	Any process that modulates the frequency, rate or extent of calcium-dependent activation of synaptic vesicle fusion.	tmpzr1t_l9r_go_relaxed.owl								bc	2018-04-18T12:47:38Z					biological_process											owl:Class	
GO:0099502	biolink:NamedThing	calcium-dependent activation of synaptic vesicle fusion	The regulatory process by which increased cytosolic calcium levels lead to the the fusion of synaptic vesicles with the presynaptic active zone membrane by bringing primed synaptic vesicle membrane into contact with membrane presynaptic active zone membrane.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0140253	biolink:NamedThing	cell-cell fusion	A cellular process in which two or more cells combine together, their plasma membrane fusing, producing a single cell. In some cases, nuclei fuse, producing a polyploid cell, while in other cases, nuclei remain separate, producing a syncytium.	tmpzr1t_l9r_go_relaxed.owl	cell cell fusion|cell fusion	https://github.com/geneontology/go-ontology/issues/15939						pg	2018-08-13T18:38:18Z					biological_process											owl:Class	
GO:0072287	biolink:NamedThing	metanephric distal tubule morphogenesis	The process in which the anatomical structures of a metanephric distal tubule are generated and organized. The metanephric distal tubule is a metanephric nephron tubule that begins at the macula densa and extends to the metanephric connecting tubule.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-04-09T03:41:47Z					biological_process											owl:Class	
GO:0019778	biolink:NamedThing	Atg12 activating enzyme activity	Catalysis of the activation of the small ubiquitin-related modifier APG12, through the formation of an ATP-dependent high-energy thiolester bond.	tmpzr1t_l9r_go_relaxed.owl	APG12 activating enzyme activity													molecular_function											owl:Class	
GO:0005948	biolink:NamedThing	acetolactate synthase complex	A dimeric (a large and a small chain) or tetrameric (two large and two small chains) enzyme complex. Catalyzes the formation of acetolactate from pyruvate.	tmpzr1t_l9r_go_relaxed.owl	acetohydroxyacid synthase complex					See also the molecular function term 'acetolactate synthase activity ; GO:0003984'.								cellular_component											owl:Class	
GO:0007547	biolink:NamedThing	germ-line processes downstream of sex determination signal	The events determining the germ-line sexual phenotype after the initial transmission of that phenotype to germ-line-specific information pathways.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0003038	biolink:NamedThing	detection of reduced oxygen by aortic body chemoreceptor signaling	The process in which information about the levels of oxygen are received and are converted to a molecular signal by chemoreceptors in an aortic body.	tmpzr1t_l9r_go_relaxed.owl	detection of reduced oxygen by aortic body chemoreceptor signalling													biological_process											owl:Class	
GO:0035905	biolink:NamedThing	ascending aorta development	The progression of the ascending aorta over time, from its initial formation to the mature structure. The ascending aorta is the portion of the aorta in a two-pass circulatory system that lies between the heart and the arch of aorta. In a two-pass circulatory system blood passes twice through the heart to supply the body once.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-06-24T11:02:01Z					biological_process											owl:Class	
GO:2000854	biolink:NamedThing	positive regulation of corticosterone secretion	Any process that activates or increases the frequency, rate or extent of corticosterone secretion.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-07-26T08:45:45Z					biological_process											owl:Class	
GO:0001850	biolink:NamedThing	complement component C3a binding	Binding to a C3a product of the complement cascade.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0031898	biolink:NamedThing	chromoplast envelope	The double lipid bilayer enclosing the chromoplast and separating its contents from the rest of the cytoplasm; includes the intermembrane space.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0060081	biolink:NamedThing	membrane hyperpolarization	The process in which membrane potential increases with respect to its steady-state potential, usually from negative potential to a more negative potential. For example, during the repolarization phase of an action potential the membrane potential often becomes more negative or hyperpolarized before returning to the steady-state resting potential.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0070755	biolink:NamedThing	negative regulation of interleukin-35 production	Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-35 production.	tmpzr1t_l9r_go_relaxed.owl	downregulation of interleukin-35 production|negative regulation of IL-35 production|down-regulation of interleukin-35 production|down regulation of interleukin-35 production|inhibition of interleukin-35 production|negative regulation of interleukin-35 biosynthetic process							mah	2009-06-23T01:34:54Z			GO:0070751		biological_process											owl:Class	
GO:0034632	biolink:NamedThing	retinol transmembrane transporter activity	Enables the transfer of retinol from one side of a membrane to the other. Retinol is vitamin A1, 2,6,6-trimethyl-1-(9'-hydroxy-3',7'-dimethylnona-1',3',5',7'-tetraenyl)cyclohex-1-ene, one of the three components that makes up vitamin A.	tmpzr1t_l9r_go_relaxed.owl	retinol transporter activity|vitamin A1 transporter activity				Reactome:R-HSA-2466749|Reactome:R-HSA-1467466|Reactome:R-HSA-2466802									molecular_function											owl:Class	
GO:0060698	biolink:NamedThing	endoribonuclease inhibitor activity	Binds to and stops, prevents or reduces the activity of endoribonuclease.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-06-08T02:37:19Z					molecular_function											owl:Class	
GO:0015676	biolink:NamedThing	vanadium ion transport	The directed movement of vanadium (V) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1901538	biolink:NamedThing	changes to DNA methylation involved in embryo development	The addition or removal of methyl groups to DNA that contributes to the epigenetic regulation of embryonic gene expression.	tmpzr1t_l9r_go_relaxed.owl	changes in DNA methylation involved in embryogenesis|changes in DNA methylation involved in embryo development|DNA methylation or demethylation involved in embryogenesis|changes in DNA methylation involved in embryonal development|DNA methylation or demethylation involved in embryonal development							jl	2012-10-25T14:53:43Z					biological_process											owl:Class	
GO:0048938	biolink:NamedThing	lateral line nerve glial cell morphogenesis involved in differentiation	The process in which the structure of a glial cell in a lateral line nerve is generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a glial cell in a lateral line nerve.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0006617	biolink:NamedThing	SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition	The process in which SRP binds to the signal peptide in a nascent protein, causing protein elongation to pause, during cotranslational membrane targeting.	tmpzr1t_l9r_go_relaxed.owl	SRP-dependent cotranslational protein-membrane targeting, signal sequence recognition|signal sequence recognition during SRP-dependent cotranslational protein targeting to membrane|SRP-dependent cotranslational membrane targeting, signal sequence recognition													biological_process											owl:Class	
GO:0030875	biolink:NamedThing	rDNA protrusion	Any of the tandem arrays of rDNA localized at the periphery of the nucleus and protruding into the nucleolus, and associated proteins. May be visible as a single or double spot by DAPI staining.	tmpzr1t_l9r_go_relaxed.owl	ribosomal DNA protrusion					Note that this component is characterized in Schizosaccharomyces, particularly with respect to the DAPI staining pattern.								cellular_component											owl:Class	
GO:0042697	biolink:NamedThing	menopause	Cessation of menstruation, occurring in (e.g.) the human female usually around the age of 50.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Menopause	Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase. To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).								biological_process											owl:Class	
GO:0033269	biolink:NamedThing	internode region of axon	An axon part that is located between the nodes of Ranvier and surrounded by compact myelin sheath.	tmpzr1t_l9r_go_relaxed.owl	internode				NIF_Subcellular:sao206157942									cellular_component											owl:Class	
GO:0007378	biolink:NamedThing	amnioserosa formation	Formation of the amnioserosa, an epithelium that occupies a hole in the embryonic dorsal epidermis. This occurs by the transformation of a narrow strip of cells at the dorsal midline of the blastoderm from columnar to squamous cells, accompanied by a lateral shift.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0036278	biolink:NamedThing	positive regulation of transcription from RNA polymerase II promoter in response to nitrogen starvation	Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a deprivation of nitrogen.	tmpzr1t_l9r_go_relaxed.owl								bf	2012-07-11T11:02:55Z					biological_process											owl:Class	
GO:0060058	biolink:NamedThing	positive regulation of apoptotic process involved in mammary gland involution	Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process of mammary epithelial cells during mammary gland involution.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of apoptosis involved in mammary gland involution													biological_process											owl:Class	
GO:0086039	biolink:NamedThing	P-type calcium transporter activity involved in regulation of cardiac muscle cell membrane potential	A calcium-transporting P-type ATPase activity involved in regulation of the plasma membrane potential.	tmpzr1t_l9r_go_relaxed.owl	calcium-transporting ATPase activity involved in regulation of cardiac muscle cell membrane potential							tb	2011-11-11T03:33:44Z					molecular_function											owl:Class	
GO:0048905	biolink:NamedThing	anterior lateral line neuromast mantle cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of an anterior lateral line neuromast mantle cell. Mantle cells are non-sensory cells that surround the sensory strip, separating the neuromast from the epidermis. Mantle cells secrete the cupula in which the ciliary bundles of all of the hair cells are embedded.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0001986	biolink:NamedThing	negative regulation of the force of heart contraction involved in baroreceptor response to increased systemic arterial blood pressure	Any process that decreases the force with which the cardiac muscles of the heart pump blood through the circulatory system as a result of the baroreceptor response to increased blood pressure.	tmpzr1t_l9r_go_relaxed.owl	decreased force of heart contraction during baroreceptor response to increased systemic arterial blood pressure|decreased strength of cardiac contraction during baroreceptor response to increased blood pressure													biological_process											owl:Class	
GO:0072546	biolink:NamedThing	EMC complex	A transmembrane protein complex located in the endoplasmic reticulum (ER) involved in the insertion of newly synthesized proteins in the membrane of the ER. In S. cerevisiae, it has six members: EMC1, EMC2, AIM27, EMC4, KRE27, and EMC6.	tmpzr1t_l9r_go_relaxed.owl	endoplasmic reticulum membrane protein complex|ER membrane protein complex	https://github.com/geneontology/go-ontology/issues/20234				Note that this complex used to be thought to be involved in ER-mitochondrial membrane tethering, which is required to facilitate lipid transfer from the ER to the mitochondrial membrane, but newer findings show that this was incorrect.		mah	2011-01-19T06:16:53Z					cellular_component											owl:Class	
GO:0016201	biolink:NamedThing	synaptic target inhibition	The process in which a neuronal cell in a multicellular organism recognizes chemorepellent signals that inhibit its growth toward the source.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0048101	biolink:NamedThing	calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity	Catalysis of the reaction: guanosine 3',5'-cyclic phosphate + H2O = guanosine 5'-phosphate. The reaction is calmodulin and calcium-sensitive.	tmpzr1t_l9r_go_relaxed.owl	calcium/calmodulin-regulated cGMP-specific phosphodiesterase activity|calcium- and calmodulin-regulated cyclic-GMP phosphodiesterase activity|calcium- and calmodulin-regulated cGMP phosphodiesterase activity|calcium- and calmodulin-regulated cGMP-specific phosphodiesterase activity													molecular_function											owl:Class	
GO:0008448	biolink:NamedThing	N-acetylglucosamine-6-phosphate deacetylase activity	Catalysis of the reaction: N-acetyl-D-glucosamine 6-phosphate + H2O = D-glucosamine 6-phosphate + acetate.	tmpzr1t_l9r_go_relaxed.owl	2-acetamido-2-deoxy-D-glucose-6-phosphate amidohydrolase activity|N-acetyl-D-glucosamine-6-phosphate amidohydrolase activity|acetylaminodeoxyglucosephosphate acetylhydrolase activity|acetylglucosamine phosphate deacetylase activity				MetaCyc:NAG6PDEACET-RXN|Reactome:R-HSA-6803789|RHEA:22936|EC:3.5.1.25									molecular_function											owl:Class	
GO:0048479	biolink:NamedThing	style development	The process whose specific outcome is the progression of the style over time, from its formation to the mature structure. The style is an elongated part of a carpel, or group of fused carpels, and it lies between the ovary and the stigma.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1990352	biolink:NamedThing	BRE1 E3 ubiquitin ligase complex	A homodimeric protein complex composed of the E3 ubiquitin-protein ligase BRE1. Plays a role in regulating association of RNA polymerase II with active genes.	tmpzr1t_l9r_go_relaxed.owl	BRE1 E3 ubiquitin-protein ligase complex|BRE1 oligomer					An example of this is BRE1 in Saccharomyces cerevisiae (UniProt symbol Q07457) in PMID:19531475 (inferred from direct assay).		bhm	2014-03-27T13:49:05Z					cellular_component											owl:Class	
GO:0052373	biolink:NamedThing	suppression of symbiont entry into host	Any process in which an organism stops, prevents, or reduces the frequency, rate or extent to which it enters into a second organism, where the two organisms are in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	down regulation by organism of entry into other organism during symbiotic interaction|inhibition by organism of entry into other organism during symbiotic interaction|negative regulation by organism of entry into other organism during symbiotic interaction|negative regulation by organism of entry into other organism involved in symbiotic interaction|down-regulation by organism of entry into other organism during symbiotic interaction|suppression of symbiont entry into host by host|downregulation by organism of entry into other organism during symbiotic interaction													biological_process											owl:Class	
GO:1902355	biolink:NamedThing	endothelial tube lumen extension involved in blood vessel lumen ensheathment	Any endothelial tube lumen extension that is involved in blood vessel lumen ensheathment.	tmpzr1t_l9r_go_relaxed.owl								pr	2013-08-14T10:22:09Z					biological_process											owl:Class	
GO:0052623	biolink:NamedThing	ADP dimethylallyltransferase activity	Catalysis of the reaction: delta2-isopentenyl diphosphate + ADP = diphosphate + N6-(delta(2)-isopentenyl)adenosine 5'-diphosphate.	tmpzr1t_l9r_go_relaxed.owl	2-isopentenyl-diphosphate:ADP 2-isopentenyltransferase activity|dimethylallyl-diphosphate:ADP dimethylallyltransferase activity|ADP isopentenyltransferase activity|2-isopentenyl-diphosphate:ADP delta2-isopentenyltransferase activity				KEGG_REACTION:R08051|EC:2.5.1.-|MetaCyc:RXN-4305			ai	2010-08-26T10:45:44Z					molecular_function											owl:Class	
GO:0000007	biolink:NamedThing	low-affinity zinc ion transmembrane transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Zn2+ = Zn2+, probably powered by proton motive force. In low-affinity transport the transporter is able to bind the solute only if it is present at very high concentrations.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0018725	biolink:NamedThing	trans-3,4-dihydrodiolphenanthrene sulfotransferase activity	Catalysis of the reaction: trans-3,4-dihydrodiolphenanthrene + 2 X-SO3(-) = 2 HX + phenanthrene-3,4-dihydrodiolsulfate conjugate.	tmpzr1t_l9r_go_relaxed.owl	trans-3,4-dihydrodiolphenanthrene sulphotransferase activity				UM-BBD_reactionID:r0558									molecular_function											owl:Class	
GO:0036121	biolink:NamedThing	double-stranded DNA helicase activity	Catalysis of the reaction: ATP + H2O = ADP + phosphate, in the presence of double-stranded DNA; drives the unwinding of a DNA helix.	tmpzr1t_l9r_go_relaxed.owl	double-stranded DNA-dependent ATP-dependent DNA helicase activity|double-stranded DNA-dependent ATPase activity|dsDNA-dependent ATP-dependent DNA helicase activity|dsDNA-dependent ATPase activity							bf	2012-02-20T02:53:51Z			GO:0033676		molecular_function											owl:Class	
GO:1902764	biolink:NamedThing	positive regulation of embryonic skeletal joint development	Any process that activates or increases the frequency, rate or extent of embryonic skeletal joint development.	tmpzr1t_l9r_go_relaxed.owl	activation of embryonic skeletal joint development|up-regulation of embryonic skeletal joint development|upregulation of embryonic skeletal joint development|up regulation of embryonic skeletal joint development							mr	2014-03-07T17:46:13Z					biological_process											owl:Class	
GO:0019586	biolink:NamedThing	galacturonate metabolic process	The chemical reactions and pathways involving galacturonate, the anion of galacturonic acid, the uronic acid formally derived from galactose by oxidation of the hydroxymethylene group at C-6 to a carboxyl group.	tmpzr1t_l9r_go_relaxed.owl	galacturonate metabolism													biological_process											owl:Class	
GO:0052922	biolink:NamedThing	hexaprenyl diphosphate synthase (geranylgeranyl-diphosphate specific) activity	Catalysis of the reaction: geranylgeranyl diphosphate + 2 isopentenyl diphosphate = 2 diphosphate + all-trans-hexaprenyl diphosphate.	tmpzr1t_l9r_go_relaxed.owl	(all-E) hexaprenyl diphosphate synthase activity|(all-trans)-hexaprenyl-diphosphate synthase activity|hexaprenyl diphosphate synthase activity|hexaprenyl pyrophosphate synthetase activity				RHEA:27555|KEGG_REACTION:R09246|EC:2.5.1.82|MetaCyc:RXN-11485									molecular_function											owl:Class	
GO:0071837	biolink:NamedThing	HMG box domain binding	Binding to an HMG box domain, a protein domain that consists of three helices in an irregular array. HMG-box domains are found in one or more copies in HMG-box proteins, which form a large, diverse family involved in the regulation of DNA-dependent processes such as transcription, replication, and strand repair, all of which require the bending and unwinding of chromatin.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-09-10T12:05:45Z					molecular_function											owl:Class	
GO:0072520	biolink:NamedThing	seminiferous tubule development	The reproductive developmental process whose specific outcome is the progression of the seminiferous tubule over time, from its formation to the mature structure. Seminiferous tubules are ducts located in the testicles, and are the specific location of meiosis, and the subsequent creation of gametes, namely spermatozoa.	tmpzr1t_l9r_go_relaxed.owl								mah	2011-01-04T12:50:36Z					biological_process											owl:Class	
GO:0018682	biolink:NamedThing	atrazine N-dealkylase activity	Catalysis of the reaction: atrazine + O2 + 2 H+ = deethylatrazine + acetaldehyde + H2O.	tmpzr1t_l9r_go_relaxed.owl	atrazine monooxygenase activity				EC:1.14.15.-|MetaCyc:R461-RXN|UM-BBD_reactionID:r0127									molecular_function											owl:Class	
GO:0070047	biolink:NamedThing	synaptobrevin 2-SNAP-25-syntaxin-4 complex	A SNARE complex that contains synaptobrevin 2 (VAMP2), SNAP-25, and syntaxin 4 (or orthologs thereof).	tmpzr1t_l9r_go_relaxed.owl	Stx4-Snap25-Vamp2 complex|SNARE complex (Stx4, Snap25, Vamp2)													cellular_component											owl:Class	
GO:0140671	biolink:NamedThing	ADA complex	A chromatin remodelling complex that regulates transcription via acetylation primarily of nucleosomal histones H3 and H2B. In budding yeast shares the histone acetylation (HAT) module of ADA2-GCN5-NGG1-SGF29 with the related SAGA complex.	tmpzr1t_l9r_go_relaxed.owl	ADA histone acetyltransferase complex|ADA HAT complex|scADA|Ada2/Gcn5/Ada3 transcription activator complex	https://github.com/geneontology/go-ontology/issues/21335						pg	2021-06-25T11:02:49Z					cellular_component											owl:Class	
GO:0103050	biolink:NamedThing	isobutyraldehyde reductase activity	Catalysis of the reaction: isobutanol + NADP <=> isobutyraldehyde + NADPH + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN0-7119									molecular_function											owl:Class	
GO:0001120	biolink:NamedThing	protein-DNA complex remodeling	The acquisition, loss, or modification of macromolecules within a protein-DNA complex, resulting in the alteration of an existing complex.	tmpzr1t_l9r_go_relaxed.owl								krc	2010-12-03T04:17:15Z					biological_process											owl:Class	
GO:0018439	biolink:NamedThing	peptidyl-L-leucine methyl ester biosynthetic process from peptidyl-leucine	The modification of a C-terminal peptidyl-leucine to form peptidyl-L-leucine methyl ester.	tmpzr1t_l9r_go_relaxed.owl	peptidyl-leucine esterification				RESID:AA0299							GO:0018440		biological_process											owl:Class	
GO:0061654	biolink:NamedThing	NEDD8 conjugating enzyme activity	Isoenergetic transfer of NEDD8 from one protein to another via the reaction X-NEDD8 + Y -> Y-NEDD8 + X, where both the X-NEDD8 and Y-NEDD8 linkages are thioester bonds between the C-terminal amino acid of NEDD8 and a sulfhydryl side group of a cysteine residue.	tmpzr1t_l9r_go_relaxed.owl	E2							dph	2014-11-06T13:27:56Z					molecular_function											owl:Class	
GO:1990120	biolink:NamedThing	messenger ribonucleoprotein complex assembly	The aggregation, arrangement and bonding together of proteins and messenger RNA (mRNA) molecules to form a messenger ribonucleoprotein (mRNP) complex.	tmpzr1t_l9r_go_relaxed.owl	mRNP assembly|mRNA-protein complex assembly|mRNP complex assembly|messenger ribonucleoprotein assembly							rb	2013-06-11T21:18:20Z					biological_process											owl:Class	
GO:0034983	biolink:NamedThing	peptidyl-lysine deacetylation	The removal of an acetyl group from an acetylated lysine residue in a peptide or protein.	tmpzr1t_l9r_go_relaxed.owl	protein lysine acetylation													biological_process											owl:Class	
GO:0034523	biolink:NamedThing	3-formylsalicylate oxidase activity	Catalysis of the reaction: 3-formylsalicylic acid + O2 + H2O = 2-hydroxyisophthalic acid + hydrogen peroxide.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0777									molecular_function											owl:Class	
GO:0047612	biolink:NamedThing	acid-CoA ligase (GDP-forming) activity	Catalysis of the reaction: a carboxylate + CoA + GTP = acyl-CoA + GDP + H(+) + phosphate.	tmpzr1t_l9r_go_relaxed.owl	acyl-CoA synthetase (GDP-forming) activity|acid:CoA ligase (GDP-forming)|acyl coenzyme A synthetase (guanosine diphosphate forming)				EC:6.2.1.10|MetaCyc:ACID--COA-LIGASE-GDP-FORMING-RXN|KEGG_REACTION:R00394|RHEA:10968									molecular_function											owl:Class	
GO:0009389	biolink:NamedThing	dimethyl sulfoxide reductase activity	Catalysis of the reaction: dimethyl sulfoxide + H+ = dimethyl sulfide + H2O.	tmpzr1t_l9r_go_relaxed.owl	dimethyl sulphoxide reductase activity				UM-BBD_reactionID:r0207|EC:1.8.99.-									molecular_function											owl:Class	
GO:0061680	biolink:NamedThing	Entner-Doudoroff pathway through gluconate to D-glyceraldehyde	The Entner-Doudoroff pathway that proceeds through a D-gluconate intermediate and yields pyruvate and D-glyceraldehyde.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:ENTNER-DOUDOROFF-PWY-II			dph	2015-01-22T08:51:31Z					biological_process											owl:Class	
GO:1990249	biolink:NamedThing	nucleotide-excision repair, DNA damage recognition complex	A protein complex that is capable of identifying lesions in DNA, such as pyrimidine-dimers, intrastrand cross-links, and bulky adducts. The wide range of substrate specificity suggests that the repair complex recognizes distortions in the DNA helix. It subsequently recruits a nucleotide-excision repair, preincision complex.	tmpzr1t_l9r_go_relaxed.owl								bhm	2013-12-05T16:26:51Z					cellular_component											owl:Class	
GO:0060945	biolink:NamedThing	cardiac neuron differentiation	The process in which a relatively unspecialized cell acquires specialized features of a neuron of the heart.	tmpzr1t_l9r_go_relaxed.owl	heart neuron differentiation							dph	2009-09-29T02:45:33Z					biological_process											owl:Class	
GO:1904272	biolink:NamedThing	L-tryptophan import across plasma membrane	The directed movement of L-tryptophan from outside of a cell, across the plasma membrane and into the cytosol.	tmpzr1t_l9r_go_relaxed.owl								kmv	2015-05-29T13:39:27Z					biological_process											owl:Class	
GO:0021826	biolink:NamedThing	substrate-independent telencephalic tangential migration	The process where neuronal precursors migrate tangentially in the telencephalon, primarily guided by interactions that do not require cell-cell contact.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0017071	biolink:NamedThing	intracellular cyclic nucleotide activated cation channel complex	A protein complex that forms a transmembrane channel through which cations ions may pass in response to an intracellular cyclic nucleotide binding to the channel complex or one of its constituent parts.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0086044	biolink:NamedThing	atrial cardiac muscle cell to AV node cell communication by electrical coupling	The process that mediates signaling interactions between an atrial cardiomyocyte and an AV node cell by transfer of current between their adjacent cytoplasms via intercellular protein channels.	tmpzr1t_l9r_go_relaxed.owl	atrial cardiomyocyte to atrioventricular node cell communication by electrical coupling|atrial cardiomyocyte to AV node cell communication by electrical coupling							dph	2011-11-15T02:51:29Z					biological_process											owl:Class	
GO:0036016	biolink:NamedThing	cellular response to interleukin-3	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-3 stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to IL-3							bf	2011-10-12T10:09:10Z					biological_process											owl:Class	
GO:0097627	biolink:NamedThing	high-affinity L-ornithine transmembrane transporter activity	Enables the transfer of L-ornithine from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.	tmpzr1t_l9r_go_relaxed.owl	high affinity L-ornithine transmembrane transporter activity							pr	2014-08-20T14:26:33Z					molecular_function											owl:Class	
GO:0033150	biolink:NamedThing	cytoskeletal calyx	A large cytoskeletal structure located at the posterior end of the perinuclear theca of a mammalian sperm head. The nucleus is tightly associated with the calyx, which contains calicin and basic cylicin proteins.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0031840	biolink:NamedThing	type 2 neuromedin U receptor binding	Binding to a type 2 neuromedin U receptor.	tmpzr1t_l9r_go_relaxed.owl	type 2 neuromedin U receptor ligand													molecular_function											owl:Class	
GO:0061634	biolink:NamedThing	alpha-D-xyloside xylohydrolase	Catalysis of the hydrolysis of terminal, non-reducing alpha-D-xylose residues with release of alpha-D-xylose.	tmpzr1t_l9r_go_relaxed.owl	alpha-xylosidase				EC:3.2.1.177			dph	2014-07-28T08:12:39Z					molecular_function											owl:Class	
GO:0140576	biolink:NamedThing	ascorbate homeostasis	Any process involved in the maintenance of an internal steady state of ascorbate at the level of a cell.	tmpzr1t_l9r_go_relaxed.owl	cellular ascorbate homeostasis	https://github.com/geneontology/go-ontology/issues/20602|https://github.com/geneontology/go-ontology/issues/20672						pg	2021-01-07T16:50:44Z					biological_process											owl:Class	
GO:0048045	biolink:NamedThing	trans-pentaprenyltranstransferase activity	Catalysis of the reaction: all-trans-pentaprenyl diphosphate + isopentenyl diphosphate = all-trans-hexaprenyl diphosphate + diphosphate.	tmpzr1t_l9r_go_relaxed.owl	hexaprenyl pyrophosphate synthetase activity|all-trans-hexaprenyl-diphosphate synthase activity|all-trans-pentaprenyl-diphosphate:isopentenyl-diphosphate pentaprenyltranstransferase activity|hexaprenyl diphosphate synthase activity				KEGG_REACTION:R05613|RHEA:22632									molecular_function											owl:Class	
GO:0018541	biolink:NamedThing	p-benzoquinone reductase (NADPH) activity	Catalysis of the reaction: 1,4-benzoquinone + H(+) + NADPH = hydroquinone + NADP(+).	tmpzr1t_l9r_go_relaxed.owl	NADPH:p-benzoquinone oxidoreductase activity				KEGG_REACTION:R05244|UM-BBD_enzymeID:e0422|MetaCyc:1.6.5.6-RXN|EC:1.6.5.6|RHEA:23488									molecular_function											owl:Class	
GO:0048224	biolink:NamedThing	lignin network	An extracellular matrix part that consists of lignin in the form of a three-dimensional polymeric network. Lignins are complex racemic aromatic heteropolymers derived from a variety of phenylpropane monomers coupled together by an assortment of carbon-carbon and ether linkages. Lignin is crucial for structural integrity of the cell wall and stiffness and strength of the stem. In addition, lignin waterproofs the cell wall, enabling transport of water and solutes through the vascular system, and plays a role in protecting plants against pathogens.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0030487	biolink:NamedThing	inositol-4,5-bisphosphate 5-phosphatase activity	Catalysis of the reaction: 1D-myo-inositol 4,5-bisphosphate + H2O = 1D-myo-inositol 4-phosphate + phosphate.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0089702	biolink:NamedThing	undecaprenyl-phosphate glucose phosphotransferase activity	Catalysis of the reaction: UDP-glucose + ditrans,octacis-undecaprenyl phosphate = UMP + alpha-D-glucopyranosyl-diphospho-ditrans,octacis-undecaprenol.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0019358	biolink:NamedThing	nicotinate nucleotide salvage	The generation of nicotinate nucleotide without de novo synthesis.	tmpzr1t_l9r_go_relaxed.owl	nicotinate nucleotide biosynthetic process, salvage pathway|nicotinate nucleotide biosynthesis, salvage pathway				MetaCyc:PYRIDNUCSAL-PWY|MetaCyc:PWY-5381									biological_process											owl:Class	
GO:0102555	biolink:NamedThing	octanoyl transferase activity (acting on glycine-cleavage complex H protein)	Catalysis of the reaction: [glycine cleavage system lipoyl-carrier protein]-L-lysine + octanoyl-ACP = H+ + a [glycine-cleavage complex H protein] N6-octanoyl-L-lysine + a holo-[acyl-carrier protein].	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-14966|EC:2.3.1.181|RHEA:17665									molecular_function											owl:Class	
GO:0048203	biolink:NamedThing	vesicle targeting, trans-Golgi to endosome	The process in which vesicles are directed to specific destination membranes during transport from the trans-Golgi to the endosome.	tmpzr1t_l9r_go_relaxed.owl	trans-Golgi to endosome targeting													biological_process											owl:Class	
GO:0001987	biolink:NamedThing	vasoconstriction of artery involved in baroreceptor response to lowering of systemic arterial blood pressure	A process that is triggered by vasomotor excitation and results in a decrease in the diameter of an artery during the baroreceptor response to decreased blood pressure.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0039540	biolink:NamedThing	suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity	Any process in which a virus stops, prevents, or reduces a host viral-induced cytoplasmic pattern recognition receptor signaling pathway by inhibiting the activity of RIG-1 (also known as DDX58). The cytoplasmic pattern recognition RIG-I recognizes viral RNA synthesized during active viral replication and signals to protect the host against viral infection, for example by inducing the expression of antiviral cytokines.	tmpzr1t_l9r_go_relaxed.owl	inhibition by virus of host RIG-I signaling|inhibition by virus of host RIG-I|inhibition of host DDX58/RIG-I by virus|inhibition by virus of host DDX58 activity|suppression by virus of host RIG-I signalling pathway|suppression by virus of host DDX58 signaling pathway|suppression by virus of host RIG-I signaling pathway|suppression by virus of host RIG-I activity	https://github.com/geneontology/go-ontology/issues/21984				This term is for annotation of viral proteins that counteract the host anti-viral innate immune response initiated by host RIG-I, either by binding and inhibiting host RIG-I directly, or by interfering with other processes so that RIG-I is unable to carry out its normal function (e.g. by processing viral RNA so it cannot be recognized by RIG-I, or by promoting the degradation of RIG-I).		bf	2012-01-18T02:24:20Z			GO:0039538		biological_process											owl:Class	
GO:0018362	biolink:NamedThing	peroxidase-heme linkage via dihydroxyheme-L-aspartyl ester-L-glutamyl ester	The covalent linkage of heme to peroxidase via dihydroxyheme-L-aspartyl ester-L-glutamyl ester.	tmpzr1t_l9r_go_relaxed.owl	peroxidase-haem linkage via dihydroxyhaem-L-aspartyl ester-L-glutamyl ester				RESID:AA0279							GO:0019924		biological_process											owl:Class	
GO:0043152	biolink:NamedThing	induction of bacterial agglutination	Any process in which infecting bacteria are clumped together by a host organism.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0019426	biolink:NamedThing	bisulfite reduction	The chemical reactions and pathways resulting in the reduction of sulfate to thiosulfate via bisulfite.	tmpzr1t_l9r_go_relaxed.owl	bisulphite reduction				MetaCyc:P224-PWY									biological_process											owl:Class	
GO:0001605	biolink:NamedThing	adrenomedullin receptor activity	Combining with adrenomedullin to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	G10D receptor													molecular_function											owl:Class	
GO:0061143	biolink:NamedThing	alveolar primary septum development	The progression of a primary alveolar septum over time, from its formation to the mature structure. A primary alveolar septum is a specialized epithelium that surrounds the saccule as it forms.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-05-25T10:21:27Z					biological_process											owl:Class	
GO:0050274	biolink:NamedThing	salicyl-alcohol beta-D-glucosyltransferase activity	Catalysis of the reaction: salicyl alcohol + UDP-D-glucose = H(+) + salicin + UDP.	tmpzr1t_l9r_go_relaxed.owl	UDPglucose:salicyl alcohol phenyl-glucosyltransferase activity|salicyl-alcohol b-D-glucosyltransferase activity|UDP-glucose:salicyl-alcohol beta-D-glucosyltransferase activity|UDPglucose:salicyl-alcohol beta-D-glucosyltransferase activity|uridine diphosphoglucose-salicyl alcohol 2-glucosyltransferase activity|salicyl-alcohol glucosyltransferase activity				EC:2.4.1.172|RHEA:11512|MetaCyc:SALICYL-ALCOHOL-GLUCOSYLTRANSFERASE-RXN|KEGG_REACTION:R03558									molecular_function											owl:Class	
GO:0047685	biolink:NamedThing	amine sulfotransferase activity	Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + an amine = adenosine 3',5'-bisphosphate + a sulfamate.	tmpzr1t_l9r_go_relaxed.owl	arylamine sulfotransferase activity|3'-phosphoadenylyl-sulfate:amine N-sulfotransferase activity|amine sulphotransferase activity|amine N-sulfotransferase activity				EC:2.8.2.3|MetaCyc:ARYLAMINE-SULFOTRANSFERASE-RXN|RHEA:24136									molecular_function											owl:Class	
GO:0010399	biolink:NamedThing	rhamnogalacturonan I backbone metabolic process	The chemical reactions and pathways involving the alternating alpha-(1->2)-linked rhamnose and alpha-(1->2)-linked B-galacturonic acid residues of the rhamnogalacturonan I backbone.	tmpzr1t_l9r_go_relaxed.owl	rhamnogalacturonan I backbone metabolism													biological_process											owl:Class	
GO:0039710	biolink:NamedThing	cytoplasmic icosahedral capsid assembly	The assembly of an icosahedral viral capsid in the cytoplasm. Often occurs by assembling around the viral genome.	tmpzr1t_l9r_go_relaxed.owl								bf	2013-11-28T15:20:50Z					biological_process											owl:Class	
GO:0018136	biolink:NamedThing	peptidyl-thiazoline dehydrogenase activity	Catalysis of the reduction of a peptide-linked thiazoline to thiazole.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0046179	biolink:NamedThing	keto-D-gluconate biosynthetic process	The chemical reactions and pathways resulting in the formation of keto-D-gluconate, the anion of keto-D-gluconic acid, an aldonic acid derived from glucose.	tmpzr1t_l9r_go_relaxed.owl	keto-D-gluconate anabolism|keto-D-gluconate synthesis|keto-D-gluconate biosynthesis|keto-D-gluconate formation													biological_process											owl:Class	
GO:0047598	biolink:NamedThing	7-dehydrocholesterol reductase activity	Catalysis of the reaction: cholesterol + NADP+ = cholesta-5,7-dien-3-beta-ol + NADPH + H+.	tmpzr1t_l9r_go_relaxed.owl	7-DHC reductase activity|sterol Delta(7)-reductase activity|sterol delta7-reductase activity|cholesterol:NADP+ delta7-oxidoreductase activity				EC:1.3.1.21|Reactome:R-HSA-6807055|RHEA:23984|MetaCyc:RXN66-323|Reactome:R-HSA-196402									molecular_function											owl:Class	
GO:0071291	biolink:NamedThing	cellular response to selenium ion	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from selenium ion.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-12-10T04:15:52Z					biological_process											owl:Class	
GO:0052796	biolink:NamedThing	exo-alpha-(2->8)-sialidase activity	Catalysis of the hydrolysis of alpha-(2->8)-glycosidic linkages of terminal sialic residues in substrates.	tmpzr1t_l9r_go_relaxed.owl	exo-alpha-(2,8)-sialidase activity|exo-alpha-2,8-sialidase activity				EC:3.2.1.18									molecular_function											owl:Class	
GO:0061897	biolink:NamedThing	all-trans retinal 3,4-desaturase activity	Catalysis of the reaction: all-trans-retinal + 2 H(+) + O2 + 2 reduced [adrenodoxin] = all-trans-3,4-didehydro retinal + 2 H2O + 2 oxidized [adrenodoxin].	tmpzr1t_l9r_go_relaxed.owl								dph	2017-06-12T14:56:58Z					molecular_function											owl:Class	
GO:0072764	biolink:NamedThing	cellular response to reversine	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reversine stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2012-11-09T11:52:22Z					biological_process											owl:Class	
GO:0010295	biolink:NamedThing	(+)-abscisic acid 8'-hydroxylase activity	Catalysis of the reaction: (+)-abscisate + H(+) + NADPH + O(2) = (+)-8'-hydroxyabscisate + H(2)O + NADP(+).	tmpzr1t_l9r_go_relaxed.owl	ABA 8'-hydroxylase activity|abscisic acid 8'-hydroxylase activity|abscisate,NADPH:oxygen oxidoreductase (8'-hydroxylating)|(+)-ABA 8'-hydroxylase activity|ABA 8'-Hydroxylase activity, Abscisate 8'-hydroxylase activity				RHEA:12897|MetaCyc:1.14.13.93-RXN|KEGG_REACTION:R07202|EC:1.14.14.137									molecular_function											owl:Class	
GO:1902584	biolink:NamedThing	positive regulation of response to water deprivation	Any process that activates or increases the frequency, rate or extent of response to water deprivation.	tmpzr1t_l9r_go_relaxed.owl	upregulation of drought tolerance|activation of response to dehydration|activation of response to drought|upregulation of response to water deprivation|activation of drought tolerance|positive regulation of response to dehydration|up regulation of response to water deprivation|up-regulation of drought tolerance|up-regulation of response to drought|positive regulation of response to thirst|positive regulation of drought tolerance|up regulation of response to drought|up-regulation of response to thirst|activation of response to thirst|up regulation of response to dehydration|upregulation of response to drought|upregulation of response to dehydration|activation of response to water deprivation|up regulation of drought tolerance|up regulation of response to thirst|positive regulation of response to drought|up-regulation of response to water deprivation|upregulation of response to thirst|up-regulation of response to dehydration							tb	2013-12-19T00:31:58Z					biological_process											owl:Class	
GO:0003972	biolink:NamedThing	RNA ligase (ATP) activity	Catalysis of the reaction: ATP + ribonucleotide(n) + ribonucleotide(m) = AMP + diphosphate + ribonucleotide(n+m).	tmpzr1t_l9r_go_relaxed.owl	ribonucleic ligase activity|polyribonucleotide synthase (ATP) activity|polyribonucleotide ligase activity|poly(ribonucleotide):poly(ribonucleotide) ligase (AMP-forming)				MetaCyc:RNA-LIGASE-ATP-RXN|EC:6.5.1.3|Reactome:R-HSA-5696816									molecular_function											owl:Class	
GO:0018646	biolink:NamedThing	1-hydroxy-2-oxolimonene 1,2-monooxygenase activity	Catalysis of the reaction: (1S,4R)-1-hydroxy-2-oxolimonene + NADPH + O2 = NADP+ + OH- + (3R)-3-isopropenyl-6-oxoheptanoate.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0736|EC:1.14.13.-									molecular_function											owl:Class	
GO:0102160	biolink:NamedThing	cyanidin-3-O-glucoside 2-O-glucuronosyltransferase activity	Catalysis of the reaction: cyanidin 3-O-beta-D-glucoside betaine + UDP-alpha-D-glucuronate <=> H+ + cyanidin 3-O-beta-(2-O-beta-D-glucuronosyl)-beta-D-glucoside + UDP.	tmpzr1t_l9r_go_relaxed.owl					EC:2.4.1.254|RHEA:28258|MetaCyc:RXN-11756									molecular_function											owl:Class	
GO:0070680	biolink:NamedThing	asparaginyl-tRNAAsn biosynthesis via transamidation	A tRNA aminoacylation process in which asparaginyl-tRNAAsn is formed by a tRNA-dependent two-step pathway. In the first step a non-discriminating aspartyl-tRNA synthetase generates the misacylated L-aspartyl-tRNAAsn species, and in the second step it is amidated to the correctly charged L-asparaginyl-tRNAAsn by the heterotrimeric aspartyl-tRNAAsn amidotransferase.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:PWY490-4			mah	2009-06-02T03:11:19Z					biological_process											owl:Class	
GO:0045458	biolink:NamedThing	recombination within rDNA repeats	Genetic recombination within the DNA of the genes coding for ribosomal RNA.	tmpzr1t_l9r_go_relaxed.owl	recombination within ribosomal DNA repeats					Note that this term was reinstated from obsolete.								biological_process											owl:Class	
GO:0140560	biolink:NamedThing	xylosyl alpha-1,3-xylosyltransferase activity	Catalyzes the reaction: UDP-alpha-D-xylose + [protein with EGF-like domain]-3-O-(alpha-D-xylosyl-(1->3)-beta-D-glucosyl)-L-serine <=> UDP + [protein with EGF-like domain]-3-O-(alpha-D-xylosyl-(1->3)-alpha-D-xylosyl-(1->3)-beta-D-glucosyl)-L-serine. The enzyme, found in animals and insects, is involved in the biosynthesis of the alpha-D-xylosyl-(1->3)-alpha-D-xylosyl-(1->3)- beta-D-glucosyl trisaccharide on epidermal growth factor-like (EGF- like) domains.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/16869			RHEA:22820|EC:2.4.2.62			pg	2020-11-25T13:45:18Z					molecular_function											owl:Class	
GO:0019450	biolink:NamedThing	L-cysteine catabolic process to pyruvate	The chemical reactions and pathways resulting in the breakdown of L-cysteine into other compounds, including pyruvate.	tmpzr1t_l9r_go_relaxed.owl	L-cysteine degradation to pyruvate|L-cysteine breakdown to pyruvate				MetaCyc:LCYSDEG-PWY									biological_process											owl:Class	
GO:0061334	biolink:NamedThing	cell rearrangement involved in Malpighian tubule morphogenesis	The movement of an epithelial cell with respect to other epithelial cells that contributes to the shaping of the Malpighian tubule.	tmpzr1t_l9r_go_relaxed.owl	cell migration involved in Malpighian tubule morphogenesis							dph	2010-09-28T02:04:05Z					biological_process											owl:Class	
GO:0034795	biolink:NamedThing	cyclohexane monooxygenase activity	Catalysis of the reaction: cyclohexane + O2 + NAD(P)H + H+ = cyclohexanol + NAD(P)+ + H2O.	tmpzr1t_l9r_go_relaxed.owl	cyclohexane hydroxylase activity|butane monooxygenase activity				MetaCyc:RXN-8697|UM-BBD_reactionID:r1059|KEGG_REACTION:R06945|EC:1.14.15.-									molecular_function											owl:Class	
GO:0047406	biolink:NamedThing	beta-aspartyl-N-acetylglucosaminidase activity	Catalysis of the reaction: N(4)-(beta-N-acetyl-D-glucosaminyl)-L-asparagine + H(2)O = N-acetyl-D-glucosamine + L-asparagine.	tmpzr1t_l9r_go_relaxed.owl	1-beta-aspartyl-N-acetyl-D-glucosaminylamine L-asparaginohydrolase activity|beta-aspartylacetylglucosaminidase activity				KEGG_REACTION:R01266|RHEA:12324|EC:3.2.2.11|MetaCyc:3.2.2.11-RXN									molecular_function											owl:Class	
GO:0035705	biolink:NamedThing	T-helper 17 cell chemotaxis	The directed movement of a T-helper 17 cell in response to an external stimulus.	tmpzr1t_l9r_go_relaxed.owl	Th17 cell chemotaxis							bf	2011-03-02T02:35:16Z					biological_process											owl:Class	
GO:0097002	biolink:NamedThing	mitochondrial inner boundary membrane	The portion of the mitochondrial inner membrane that is not invaginated to form cristae. The inner boundary membrane lies parallel to the outer membrane.	tmpzr1t_l9r_go_relaxed.owl	inner bounding mitochondrial membrane				NIF_Subcellular:sao18461326			pr	2011-03-10T04:11:50Z					cellular_component											owl:Class	
GO:0018623	biolink:NamedThing	benzoate 1,2-dioxygenase activity	Catalysis of the reaction: benzoate + NADH + H+ + O2 = catechol + CO2 + NAD+.	tmpzr1t_l9r_go_relaxed.owl	benzoate,NADH:oxygen oxidoreductase (1,2-hydroxylating, decarboxylating)|benzoate dioxygenase activity|benzoic hydroxylase activity|benzoate,NADH:oxygen oxidoreductase (1,2-hydroxylating)|benzoate hydroxylase activity				RHEA:12633|UM-BBD_enzymeID:e0154|EC:1.14.12.10|MetaCyc:BENZOATE-12-DIOXYGENASE-RXN									molecular_function											owl:Class	
GO:1904731	biolink:NamedThing	positive regulation of intestinal lipid absorption	Any process that activates or increases the frequency, rate or extent of intestinal lipid absorption.	tmpzr1t_l9r_go_relaxed.owl	up regulation of intestinal lipid absorption|activation of intestinal lipid absorption|up-regulation of intestinal lipid absorption|upregulation of intestinal lipid absorption							sl	2015-10-14T15:25:10Z					biological_process											owl:Class	
GO:1990374	biolink:NamedThing	Kir2 inward rectifier potassium channel complex	A inward rectifier potassium channel complex. Homo- or heterotetramer composed of subunits of the eukaryotic Kir2 protein family. Plays a key role in maintaining the correct resting potential in eukaryotic cells.	tmpzr1t_l9r_go_relaxed.owl	Kir2.1 complex					An example of this is Kcnj2 in mouse (P35561) in PMID:16834334 (inferred from direct assay).		bhm	2014-04-25T15:29:15Z					cellular_component											owl:Class	
GO:0072482	biolink:NamedThing	response to mitotic cell cycle spindle orientation checkpoint signaling	A process that occurs in response to signals generated as a result of mitotic cell cycle spindle orientation checkpoint signaling.	tmpzr1t_l9r_go_relaxed.owl	response to signal involved in mitotic cell cycle spindle orientation checkpoint|mitotic cell cycle spindle orientation checkpoint effector process							mah	2010-12-09T12:11:56Z					biological_process											owl:Class	
GO:0140649	biolink:NamedThing	cell-to-cell migration by invasive hypha	The directional movement of a hyphal filament from one host cell to another. This process involves the clearance of plant-derived plasmodesmal occlusion materials, cytoskeleton based constriction of invasive hypha to traverse plasmodesmata. Septins and F-actin are reorganized into an hourglass shape at the point of maximum hyphal constriction.	tmpzr1t_l9r_go_relaxed.owl	host tissue colonization|invasive hyphae formation|plant tissue colonization|invasive growth	https://github.com/geneontology/go-ontology/issues/21125				Do not confuse with ' GO:0036267 invasive filamentous growth ', which doesn't include invasion of cells within the host.		pg	2021-05-25T07:42:38Z					biological_process											owl:Class	
GO:0050028	biolink:NamedThing	L-lysine-lactamase activity	Catalysis of the reaction: L-2-aminohexano-6-lactam + H(2)O = L-lysine.	tmpzr1t_l9r_go_relaxed.owl	L-alpha-aminocaprolactam hydrolase activity|L-lysine-1,6-lactam lactamhydrolase activity|L-lysinamidase activity				RHEA:21388|KEGG_REACTION:R00463|EC:3.5.2.11|MetaCyc:L-LYSINE-LACTAMASE-RXN									molecular_function											owl:Class	
GO:0033065	biolink:NamedThing	Rad51C-XRCC3 complex	A DNA recombinase mediator complex that contains the Rad51 paralogs RAD51C and XRCC3, or orthologs thereof.	tmpzr1t_l9r_go_relaxed.owl	CX3 complex													cellular_component											owl:Class	
GO:0000384	biolink:NamedThing	first spliceosomal transesterification activity	Catalysis of the first transesterification reaction of spliceosomal mRNA splicing. The intron branch site adenosine is the nucleophile attacking the 5' splice site, resulting in cleavage at this position. In cis splicing, this is the step that forms a lariat structure of the intron RNA, while it is still joined to the 3' exon.	tmpzr1t_l9r_go_relaxed.owl	lariat formation, 5'-splice site cleavage													molecular_function											owl:Class	
GO:0001691	biolink:NamedThing	pseudophosphatase activity	Maintains the phosphorylation state of certain molecules by associating with them and preventing them from associating with active phosphatases, and thus inhibiting the enzyme activity without interacting with the enzyme. Often pertains to proteins belonging to dual-specificity phosphatase family but lacking critical active site residues.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0047618	biolink:NamedThing	acylagmatine amidase activity	Catalysis of the reaction: N(4)-benzoylagmatine + H(2)O = agmatine + benzoate.	tmpzr1t_l9r_go_relaxed.owl	benzoylagmatine amidohydrolase activity|acylagmatine amidohydrolase activity|acylagmatine deacylase activity				RHEA:15065|KEGG_REACTION:R01425|MetaCyc:ACYLAGMATINE-AMIDASE-RXN|EC:3.5.1.40									molecular_function											owl:Class	
GO:0090350	biolink:NamedThing	negative regulation of cellular organofluorine metabolic process	Any process that decreases the rate, frequency or extent of the chemical reactions and pathways involving organofluorine compounds, as carried out by individual cells.	tmpzr1t_l9r_go_relaxed.owl								tb	2010-06-02T10:36:42Z					biological_process											owl:Class	
GO:0003113	biolink:NamedThing	positive regulation of heart rate by neuronal norepinephrine	The process in which the secretion of norepinephrine released from nerve endings increases the rate of heart muscle contraction.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of heart rate by neuronal noradrenaline													biological_process											owl:Class	
GO:0106331	biolink:NamedThing	sialate 4-O-acetylesterase activity	Catalysis of the reaction: H2O + N-acetyl-4-O-acetylneuraminate = acetate + H(+) + N-acetylneuraminate.	tmpzr1t_l9r_go_relaxed.owl					RHEA:25564|EC:3.1.1.53			hjd	2020-09-30T19:40:24Z					molecular_function											owl:Class	
GO:0043273	biolink:NamedThing	CTPase activity	Catalysis of the reaction: CTP + H2O = CDP + phosphate. May or may not be coupled to another reaction.	tmpzr1t_l9r_go_relaxed.owl	CTPase activity, coupled|single-stranded DNA-dependent CTPase activity|cytidine triphosphatase activity	https://github.com/geneontology/go-ontology/issues/19078						dph	2015-11-11T13:05:32Z			GO:0061747|GO:0061748		molecular_function											owl:Class	
GO:0102217	biolink:NamedThing	6-phosphoglucan, water dikinase activity	Catalysis of the reaction: n ATP + n H2O + a 6-phosphogluco-maltodextrin = n AMP + n hydrogenphosphate + a poly-6-phosphogluco-maltodextrin.	tmpzr1t_l9r_go_relaxed.owl					RHEA:10256|EC:2.7.9.5|MetaCyc:RXN-12202									molecular_function											owl:Class	
GO:0070331	biolink:NamedThing	CD20-Lck-Fyn complex	A protein complex that contains the cell-surface protein CD20 and the Src family tyrosine kinases Lck and Fyn.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0140561	biolink:NamedThing	EGF-domain serine glucosyltransferase activity	Catalysis of the reaction: UDP-alpha-D-glucose + [protein with EGF-like domain]-L-serine <=> UDP + [protein with EGF-like domain]-3-O-(beta-D-glucosyl)-L-serine.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/16869			EC:2.4.1.376|RHEA:58116			pg	2020-11-25T14:19:23Z					molecular_function											owl:Class	
GO:0102512	biolink:NamedThing	delphinidin 3-O-glucoside 5-O-glucosyltransferase (acyl-glucose dependent) activity	Catalysis of the reaction: delphinidin 3-O-beta-D-glucoside + 1-O-vanilloyl-beta-D-glucose <=> delphinidin 3-O-beta-D-glucoside-5-O-beta-D-glucoside betaine + vanillate + H+.	tmpzr1t_l9r_go_relaxed.owl					EC:2.4.1.299|MetaCyc:RXN-14441									molecular_function											owl:Class	
GO:0014846	biolink:NamedThing	esophagus smooth muscle contraction	A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the esophagus. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The esophagus is the muscular membranous segment between the pharynx and the stomach in the upper gastrointestinal tract.	tmpzr1t_l9r_go_relaxed.owl	oesophagus smooth muscle contraction													biological_process											owl:Class	
GO:0102486	biolink:NamedThing	dCTP phosphohydrolase activity	Catalysis of the reaction: dCTP + 2 H2O = dCMP + 2 hydrogenphosphate + 2 H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-14198|EC:3.6.1.5									molecular_function											owl:Class	
GO:0019964	biolink:NamedThing	interferon-gamma binding	Binding to interferon-gamma. Interferon gamma is the only member of the type II interferon found so far.	tmpzr1t_l9r_go_relaxed.owl	IFNG binding|IFN-gamma binding|type II interferon binding													molecular_function											owl:Class	
GO:0001965	biolink:NamedThing	G-protein alpha-subunit binding	Binding to a G-protein alpha subunit. The alpha subunit binds a guanine nucleotide.	tmpzr1t_l9r_go_relaxed.owl	G-alpha protein subunit binding													molecular_function											owl:Class	
GO:0044808	biolink:NamedThing	oncostatin M production	The appearance of oncostatin M due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	tmpzr1t_l9r_go_relaxed.owl	OSM production							jl	2013-09-11T12:18:00Z					biological_process											owl:Class	
GO:0018888	biolink:NamedThing	3-chloroacrylic acid metabolic process	The chemical reactions and pathways involving 3-chloroacrylic acid, ClHC=CHCOOH, a chlorinated derivative of acrylic acid.	tmpzr1t_l9r_go_relaxed.owl	3-chloroacrylic acid metabolism				UM-BBD_pathwayID:caa									biological_process											owl:Class	
GO:0031250	biolink:NamedThing	anaerobic ribonucleoside-triphosphate reductase complex	An enzyme complex composed of 4 subunits, 2 copies of the large protein (nrdD in E. coli) and 2 copies of the small protein (nrdG in E. coli). It catalyzes the generation of 2'deoxyribonucleotides under anaerobic growth conditions. The larger subunit is the catalytic unit that is activated by the smaller iron-binding subunit.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0097412	biolink:NamedThing	hyaline inclusion	A glass-like, pale intracellular inclusion.	tmpzr1t_l9r_go_relaxed.owl	pale body				NIF_Subcellular:nlx_subcell_20090104			pr	2012-11-06T16:24:58Z					cellular_component											owl:Class	
GO:0043997	biolink:NamedThing	histone acetyltransferase activity (H4-K12 specific)	Catalysis of the reaction: acetyl-CoA + histone H4 L-lysine (position 12) = CoA + histone H4 N6-acetyl-L-lysine (position 12).	tmpzr1t_l9r_go_relaxed.owl	histone lysine N-acetyltransferase activity (H4-K12 specific)													molecular_function											owl:Class	
GO:0008413	biolink:NamedThing	8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity	Catalysis of the reaction: 8-oxo-7,8-dihydroguanosine triphosphate (8-oxo-GTP) + H2O = 8-oxo-7,8-dihydroguanosine diphosphate (8-oxo-GDP) +  phosphate. 8-oxo-7,8-dihydroguanosine triphosphate (8-oxo-GTP) is the oxidised form of the free guanine nucleotide and can act as a potent mutagenic substrate for transcription.	tmpzr1t_l9r_go_relaxed.owl	7,8-dihydro-8-oxoguanine-triphosphatase activity|8-oxo-7,8-dihydroguanosine triphosphatase activity|8-oxo-GTPase activity|8-oxo-7,8-dihydroguanine triphosphatase activity				EC:3.6.1.69|RHEA:60032									molecular_function											owl:Class	
GO:0102954	biolink:NamedThing	dalcochinase activity	Catalysis of the reaction: dalcochinin-8'-O-beta-glucoside + H2O <=> dalcochinin + D-glucopyranose.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-9162									molecular_function											owl:Class	
GO:0018498	biolink:NamedThing	2,3-dihydroxy-2,3-dihydro-phenylpropionate dehydrogenase activity	Catalysis of the reaction: cis-3-(3-carboxyethyl)-3,5-cyclohexadiene-1,2-diol + NAD+ = NADH + H+ + 3-(2,3-dihydroxyphenyl)propionate.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:PHENPRODIOLDEHYDROG-RXN|RHEA:25062|UM-BBD_enzymeID:e0308									molecular_function											owl:Class	
GO:0009779	biolink:NamedThing	noncyclic photosynthetic phosphorylation	A photosynthetic phosphorylation process in which ATP synthesis is linked to the transport of electrons from water to NADP+ with the production of NADPH and dioxygen (O2). Involves photosystem I and photosystem II.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0038141	biolink:NamedThing	ERBB4-ERBB4 complex	A homodimeric complex containing two monomers of the tyrosine kinase receptor ERBB4 (also called HER4).	tmpzr1t_l9r_go_relaxed.owl	ERBB4 homodimer							bf	2012-03-30T02:06:20Z					cellular_component											owl:Class	
GO:0000310	biolink:NamedThing	xanthine phosphoribosyltransferase activity	Catalysis of the reaction: 5-phospho-alpha-D-ribose 1-diphosphate + xanthine = (9-D-ribosylxanthine)-5'-phosphate + diphosphate.	tmpzr1t_l9r_go_relaxed.owl	xanthosine 5'-phosphate pyrophosphorylase activity|5-phospho-alpha-D-ribose-1-diphosphate:xanthine phospho-D-ribosyltransferase activity|xanthylate pyrophosphorylase activity|xanthine-guanine phosphoribosyltransferase activity|XMP pyrophosphorylase activity|XMP:diphosphate 5-phospho-alpha-D-ribosyltransferase activity|Xan phosphoribosyltransferase activity|xanthylic pyrophosphorylase activity				RHEA:10800|EC:2.4.2.22|MetaCyc:XANPRIBOSYLTRAN-RXN							GO:0009043		molecular_function											owl:Class	
GO:0001650	biolink:NamedThing	fibrillar center	A structure found most metazoan nucleoli, but not usually found in lower eukaryotes; surrounded by the dense fibrillar component; the zone of transcription from multiple copies of the pre-rRNA genes is in the border region between these two structures.	tmpzr1t_l9r_go_relaxed.owl	fibrillar centre													cellular_component											owl:Class	
GO:0004001	biolink:NamedThing	adenosine kinase activity	Catalysis of the reaction: ATP + adenosine = ADP + AMP.	tmpzr1t_l9r_go_relaxed.owl	adenosine kinase (phosphorylating)|ATP:adenosine 5'-phosphotransferase activity|adenosine 5-phosphotransferase activity				MetaCyc:ADENOSINE-KINASE-RXN|EC:2.7.1.20|Reactome:R-HSA-109624|RHEA:20824									molecular_function											owl:Class	
GO:0005297	biolink:NamedThing	proline:proton symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: proline(out) + H+(out) = proline(in) + H+(in).	tmpzr1t_l9r_go_relaxed.owl	hydrogen/proline transporter													molecular_function											owl:Class	
GO:0052810	biolink:NamedThing	1-phosphatidylinositol-5-kinase activity	Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol + ATP = a 1-phosphatidyl-1D-myo-inositol 5-phosphate + ADP + 2 H(+).	tmpzr1t_l9r_go_relaxed.owl	1-phosphatidylinositol 5-kinase activity|ATP:1-phosphatidyl-1D-myo-inositol 5-phosphotransferase activity				Reactome:R-HSA-1675810|RHEA:44680|Reactome:R-HSA-1675866			ai	2011-10-21T03:37:20Z					molecular_function											owl:Class	
GO:0003979	biolink:NamedThing	UDP-glucose 6-dehydrogenase activity	Catalysis of the reaction: H(2)O + 2 NAD(+) + UDP-alpha-D-glucose = 3 H(+) + 2 NADH + UDP-alpha-D-glucuronate.	tmpzr1t_l9r_go_relaxed.owl					EC:1.1.1.22|MetaCyc:UGD-RXN|RHEA:23596|KEGG_REACTION:R00286|Reactome:R-HSA-173597									molecular_function											owl:Class	
GO:0035277	biolink:NamedThing	spiracle morphogenesis, open tracheal system	The process in which the anatomical structures of a spiracle are generated and organized. Spiracles are the openings in the insect open tracheal system; externally they connect to the epidermis and internally they connect to the tracheal trunk.	tmpzr1t_l9r_go_relaxed.owl	spiracle morphogenesis													biological_process											owl:Class	
GO:0097123	biolink:NamedThing	cyclin A1-CDK2 complex	A protein complex consisting of cyclin A1 and cyclin-dependent kinase 2 (CDK2). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner.	tmpzr1t_l9r_go_relaxed.owl								pr	2011-08-01T01:43:18Z					cellular_component											owl:Class	
GO:0061604	biolink:NamedThing	molybdopterin-synthase sulfurtransferase activity	Catalysis of the reaction: [Molybdopterin-synthase sulfur-carrier protein]-Gly-Gly-AMP + [cysteine desulfurase]-S-sulfanyl-L-cysteine <=> AMP [molybdopterin-synthase sulfur-carrier protein]-Gly-NH-CH(2)-C(O)SH + cysteine desulfurase.	tmpzr1t_l9r_go_relaxed.owl					RHEA:48612|EC:2.8.1.11			dph	2014-02-11T11:56:16Z					molecular_function											owl:Class	
GO:0009345	biolink:NamedThing	glycine-tRNA ligase complex	A multimeric enzyme complex which, in bacteria, is usually a tetramer of two alpha and two beta chains and in eukaryotes, is usually a homodimer. Functions in the ligation of glycine and tRNA(Gly) to form glycyl-tRNA(Gly).	tmpzr1t_l9r_go_relaxed.owl	glycine-tRNA synthetase complex													cellular_component											owl:Class	
GO:0047539	biolink:NamedThing	2-deoxyglucosidase activity	Catalysis of the reaction: H2O + a 2-deoxy-alpha-D-glucoside = 2-deoxy-D-glucose + an alcohol.	tmpzr1t_l9r_go_relaxed.owl	2-deoxy-alpha-glucosidase activity|2-deoxy-alpha-D-glucosidase activity|2-deoxy-alpha-D-glucoside deoxyglucohydrolase activity				MetaCyc:2-DEOXYGLUCOSIDASE-RXN|RHEA:15317|EC:3.2.1.112									molecular_function											owl:Class	
GO:0010344	biolink:NamedThing	seed oilbody biogenesis	A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a seed oilbody. Seed oilbodies are simple organelles comprising a matrix of triglyceride surrounded by a phospholipid monolayer embedded and covered with unique proteins called oleosins. Seed oilbodies supply the energy requirements for the growth of the seedling after germination.	tmpzr1t_l9r_go_relaxed.owl	seed oil body organization|spherosome biogenesis|oleosome biogenesis													biological_process											owl:Class	
GO:1902556	biolink:NamedThing	phosphatidylinositol transporter complex	A protein complex which is capable of phosphatidylinositol transporter activity.	tmpzr1t_l9r_go_relaxed.owl	Ire1 complex homodimer|Ire1 complex homooligomer|Ire1 complex dimer					An example is PDR16 in S. cerevisiae (UniProt ID P53860) in PMID:9890948 (inferred from direct assay).		bhm	2013-12-06T16:12:25Z					cellular_component											owl:Class	
GO:0050388	biolink:NamedThing	uronate dehydrogenase activity	Catalysis of the reaction: D-galacturonate + H(2)O + NAD(+) = galactarate + 2 H(+) + NADH.	tmpzr1t_l9r_go_relaxed.owl	uronate:NAD+ 1-oxidoreductase activity|uronic acid dehydrogenase activity|uronate: NAD-oxidoreductase activity				RHEA:22404|MetaCyc:URONATE-DEHYDROGENASE-RXN|EC:1.1.1.203|KEGG_REACTION:R01981									molecular_function											owl:Class	
GO:0046965	biolink:NamedThing	retinoid X receptor binding	Binding to a retinoid X receptor.	tmpzr1t_l9r_go_relaxed.owl	RXR binding													molecular_function											owl:Class	
GO:0042974	biolink:NamedThing	retinoic acid receptor binding	Binding to a retinoic acid receptor, a ligand-regulated transcription factor belonging to the nuclear receptor superfamily.	tmpzr1t_l9r_go_relaxed.owl	RAR binding													molecular_function											owl:Class	
GO:0060210	biolink:NamedThing	metestrus	The estrous cycle phase in which there is subsiding follicular function.	tmpzr1t_l9r_go_relaxed.owl						Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase. To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).								biological_process											owl:Class	
GO:0070671	biolink:NamedThing	response to interleukin-12	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-12 stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to IL-12							mah	2009-05-29T10:02:31Z					biological_process											owl:Class	
GO:0030603	biolink:NamedThing	oxaloacetase activity	Catalysis of the reaction: H(2)O + oxaloacetate = acetate + H(+) + oxalate.	tmpzr1t_l9r_go_relaxed.owl	oxalacetic hydrolase activity|oxaloacetate acetylhydrolase activity				EC:3.7.1.1|MetaCyc:OXALOACETASE-RXN|RHEA:24432|KEGG_REACTION:R00338									molecular_function											owl:Class	
GO:0003977	biolink:NamedThing	UDP-N-acetylglucosamine diphosphorylase activity	Catalysis of the reaction: N-acetyl-alpha-D-glucosamine 1-phosphate + UTP = diphosphate + UDP-N-acetyl-alpha-D-glucosamine.	tmpzr1t_l9r_go_relaxed.owl	uridine diphosphate-N-acetylglucosamine pyrophosphorylase activity|UTP:N-acetyl-alpha-D-glucosamine-1-phosphate uridylyltransferase activity|N-acetylglucosamine-1-phosphate uridyltransferase activity|uridine diphosphoacetylglucosamine pyrophosphorylase activity|GlmU uridylyltransferase activity|acetylglucosamine 1-phosphate uridylyltransferase|UDP-acetylglucosamine pyrophosphorylase activity|uridine diphosphoacetylglucosamine phosphorylase activity|UDP-GlcNAc pyrophosphorylase activity|UDP-N-acetylglucosamine pyrophosphorylase activity|UTP:2-acetamido-2-deoxy-alpha-D-glucose-1-phosphate uridylyltransferase activity				KEGG_REACTION:R00416|Reactome:R-HSA-446204|MetaCyc:NAG1P-URIDYLTRANS-RXN|EC:2.7.7.23|RHEA:13509									molecular_function											owl:Class	
GO:0010068	biolink:NamedThing	protoderm histogenesis	The formation of the primary meristem or meristematic tissue that gives rise to the epidermis.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0047719	biolink:NamedThing	indole 2,3-dioxygenase activity	Catalysis of the reaction: indole + O(2) = 2-formamidobenzaldehyde.	tmpzr1t_l9r_go_relaxed.owl	indole:O2 oxidoreductase activity|indole-oxygen 2,3-oxidoreductase (decyclizing)|IDO|indole:oxygen 2,3-oxidoreductase (decyclizing)|indole oxidase activity				MetaCyc:INDOLE-23-DIOXYGENASE-RXN|RHEA:11212|KEGG_REACTION:R02338|EC:1.13.11.17									molecular_function											owl:Class	
GO:0097582	biolink:NamedThing	dolichyl-phosphate-mannose-protein mannosyltransferase Pmt1p-Pmt2p dimer complex	A protein dimer complex that possesses dolichyl-phosphate-mannose-protein mannosyltransferase activity and, in S. cerevisiae, is composed of Pmt1p-Pmt2p.	tmpzr1t_l9r_go_relaxed.owl	Pmt1p-Pmt2p complex							pr	2014-03-02T18:13:34Z					cellular_component											owl:Class	
GO:0120117	biolink:NamedThing	T cell meandering migration	The random-like motility observed for T cells in lymph nodes which enhances surveillance of antigens presented by major histocompatibility complex (MHC) molecules on antigen presenting cells (APCs).	tmpzr1t_l9r_go_relaxed.owl	lymph node surveillance|T cell meandering search							krc	2017-11-22T18:13:01Z					biological_process											owl:Class	
GO:0097270	biolink:NamedThing	dishabituation	The temporary recovery of response to a stimulus when a novel stimulus is added.	tmpzr1t_l9r_go_relaxed.owl								pr	2012-03-20T01:39:25Z					biological_process											owl:Class	
GO:0002100	biolink:NamedThing	tRNA wobble adenosine to inosine editing	The process in which an adenosine in position 34 of a tRNA is post-transcriptionally converted to inosine.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0099005	biolink:NamedThing	extrinsic component of postsynaptic recycling endosome membrane	The component of the postsynaptic recycling endosome membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0098931	biolink:NamedThing	virion attachment to host cell flagellum	The process by which a virion attaches to a the host cell flagellum. Some DNA bacterial viruses use flagella to attach to the host cell. This contact with the flagellum facilitates concentration of phage particles around the entry receptor on the bacterial cell surface.	tmpzr1t_l9r_go_relaxed.owl					VZ:3949									biological_process											owl:Class	
GO:0035695	biolink:NamedThing	mitophagy by induced vacuole formation	The process in which cells degrade mitochondria by inducing a vacuole-like structure which directly engulfs and degrades the unhealthy mitochondria by accumulating lysosomes.	tmpzr1t_l9r_go_relaxed.owl	MIV-mediated mitophagy					In this mechanism of mitochondrion degradation, the mitochondrion is directly engulfed by a lysosome-like vacuole. It is therefore distinct from canonical autophagy, which is mediated by a double-membrane autophagosome.		bf	2011-02-28T03:01:04Z					biological_process											owl:Class	
GO:0006707	biolink:NamedThing	cholesterol catabolic process	The chemical reactions and pathways resulting in the breakdown of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.	tmpzr1t_l9r_go_relaxed.owl	cholesterol catabolism|cholesterol breakdown|cholesterol degradation													biological_process											owl:Class	
GO:0098511	biolink:NamedThing	sensory perception of low humidity	The series of events required for an organism to detect low environmental humidity, convert this detection into a molecular signal, and recognize and characterize the signal. This is a neurological process.	tmpzr1t_l9r_go_relaxed.owl								dos	2013-09-25T14:02:02Z					biological_process											owl:Class	
GO:0050057	biolink:NamedThing	linamarin synthase activity	Catalysis of the reaction: UDP-glucose + 2-hydroxy-2-methylpropanenitrile = UDP + linamarin.	tmpzr1t_l9r_go_relaxed.owl	UDPglucose:ketone cyanohydrin beta-glucosyltransferase activity|uridine diphosphate-glucose-ketone cyanohydrin beta-glucosyltransferase activity|UDP-glucose:2-hydroxy-2-methylpropanenitrile beta-D-glucosyltransferase activity|UDPglucose:2-hydroxy-2-methylpropanenitrile beta-D-glucosyltransferase activity|uridine diphosphoglucose-ketone cyanohydrin glucosyltransferase activity|uridine diphosphoglucose-ketone glucosyltransferase activity|UDP glucose ketone cyanohydrin glucosyltransferase activity				RHEA:20009|MetaCyc:LINAMARIN-SYNTHASE-RXN|EC:2.4.1.63									molecular_function											owl:Class	
GO:1904313	biolink:NamedThing	response to methamphetamine hydrochloride	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methamphetamine hydrochloride stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to methamphetamine HCL							sl	2015-06-10T17:47:09Z					biological_process											owl:Class	
GO:0103072	biolink:NamedThing	straight chain (R)-2-hydroxy fatty acyl-CoA lyase activity	Catalysis of the reaction: a (R)-2-hydroxy even numbered straight chain 2,3,4-saturated fatty acyl CoA = formyl-CoA + an odd numbered straight chain 2,3,4-saturated fatty aldehyde.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN66-475									molecular_function											owl:Class	
GO:0047776	biolink:NamedThing	citramalate lyase activity	Catalysis of the reaction: S-citramalate = acetate + pyruvate.	tmpzr1t_l9r_go_relaxed.owl	(+)-citramalate pyruvate-lyase activity|citramalic-condensing enzyme|(S)-citramalate lyase activity|citramalate synthetase activity|citramalic synthase activity|(3S)-citramalate pyruvate-lyase activity|citramalate pyruvate-lyase activity|(3S)-citramalate pyruvate-lyase (acetate-forming)|citramalate pyruvate lyase activity				MetaCyc:CITRAMALATE-LYASE-RXN|EC:4.1.3.22|RHEA:15545|KEGG_REACTION:R00325									molecular_function											owl:Class	
GO:0014897	biolink:NamedThing	striated muscle hypertrophy	The enlargement or overgrowth of all or part of an organ due to an increase in size of muscle cells without cell division. In the case of striated muscle, this happens due to the additional synthesis of sarcomeric proteins and assembly of myofibrils.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0089707	biolink:NamedThing	L-lysine transmembrane export from vacuole	The directed movement of L-lysine out of the vacuole, across the vacuolar membrane.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0010335	biolink:NamedThing	response to non-ionic osmotic stress	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of non-ionic solutes (e.g. mannitol, sorbitol) in the environment.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0000170	biolink:NamedThing	sphingosine hydroxylase activity	Catalysis of the hydroxylation of sphingolipid long chain bases.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-428260									molecular_function											owl:Class	
GO:0033886	biolink:NamedThing	cellulose-polysulfatase activity	Catalysis of the hydrolysis of the 2- and 3-sulfate groups of the polysulfates of cellulose and charonin.	tmpzr1t_l9r_go_relaxed.owl	cellulose-sulfate sulfohydrolase activity				EC:3.1.6.7|MetaCyc:3.1.6.7-RXN									molecular_function											owl:Class	
GO:0004167	biolink:NamedThing	dopachrome isomerase activity	Catalysis of the reaction: L-dopachrome = 5,6-dihydroxyindole-2-carboxylate.	tmpzr1t_l9r_go_relaxed.owl	dopachrome-rearranging enzyme|DCF activity|dopachrome Delta(7),Delta(2)-isomerase activity|dopachrome rearranging enzyme activity|dopachrome oxidoreductase activity|dopachrome conversion activity|TRP2|L-dopachrome isomerase activity|TRP-2|L-dopachrome keto-enol isomerase activity|dopachrome tautomerase activity|TRP-1|TRP activity|dopachrome keto-enol isomerase activity|L-dopachrome-methyl ester tautomerase activity|dopachrome delta-isomerase activity|tryosinase-related protein-2|tyrosinase-related protein 2 activity|dopachrome delta7,Delta2-isomerase activity|dopachrome conversion factor activity|DCT activity				KEGG_REACTION:R03673|RHEA:13041|MetaCyc:DOPACHROME-DELTA-ISOMERASE-RXN|EC:5.3.3.12							GO:0048059		molecular_function											owl:Class	
GO:0047250	biolink:NamedThing	4-hydroxybenzoate 4-O-beta-D-glucosyltransferase activity	Catalysis of the reaction: 4-hydroxybenzoate + UDP-D-glucose = 4-(beta-D-glucosyloxy)benzoate + H(+) + UDP.	tmpzr1t_l9r_go_relaxed.owl	uridine diphosphoglucose-4-hydroxybenzoate glucosyltransferase activity|PHB-O-glucosyltransferase activity|UDP-glucose:4-hydroxybenzoate 4-O-beta-D-glucosyltransferase activity|PHB glucosyltransferase activity|p-hydroxybenzoate glucosyltransferase activity|UDP-glucose:4-(beta-D-glucopyranosyloxy)benzoic acid glucosyltransferase activity|UDPglucose:4-hydroxybenzoate 4-O-beta-D-glucosyltransferase activity|HBA glucosyltransferase activity				KEGG_REACTION:R01304|EC:2.4.1.194|MetaCyc:2.4.1.194-RXN|RHEA:15153									molecular_function											owl:Class	
GO:0034529	biolink:NamedThing	2-hydroxy-3-carboxy-benzalpyruvate hydratase-aldolase activity	Catalysis of the reaction: 2-hydroxy-3-carboxybenzalpyruvate + H2O = 3-formylsalicylic acid + pyruvate.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0792									molecular_function											owl:Class	
GO:0000432	biolink:NamedThing	positive regulation of transcription from RNA polymerase II promoter by glucose	Any process involving glucose that activates or increases the rate of transcription from an RNA polymerase II promoter.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of transcription from RNA polymerase II promoter by glucose|stimulation of transcription from RNA polymerase II promoter by glucose|up regulation of transcription from RNA polymerase II promoter by glucose|activation of transcription from RNA polymerase II promoter by glucose|upregulation of transcription from RNA polymerase II promoter by glucose													biological_process											owl:Class	
GO:0050268	biolink:NamedThing	coniferyl-alcohol dehydrogenase activity	Catalysis of the reaction: coniferyl alcohol + NADP+ = coniferyl aldehyde + NADPH.	tmpzr1t_l9r_go_relaxed.owl	coniferyl-alcohol:NADP+ oxidoreductase activity				EC:1.1.1.194|MetaCyc:RXN-2602|RHEA:22444									molecular_function											owl:Class	
GO:0018003	biolink:NamedThing	peptidyl-lysine N6-acetylation	The acetylation of the peptidyl-lysine of proteins to form the derivative peptidyl-N6-acetyl-L-lysine.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0055	See also the molecular function term 'tubulin N-acetyltransferase activity ; GO:0019799'.								biological_process											owl:Class	
GO:0043602	biolink:NamedThing	nitrate catabolic process	The chemical reactions and pathways resulting in the breakdown of nitrates, inorganic or organic salts and esters of nitric acid.	tmpzr1t_l9r_go_relaxed.owl	nitrate dissimilation|nitrate disassimilation													biological_process											owl:Class	
GO:0051071	biolink:NamedThing	4,6-pyruvylated galactose residue metabolic process	The chemical reactions and pathways involving the pyruvylated galactose residue 4-6-O-[(R)(1-carboxyethylidine)]-Gal-beta-1,3-. The galactose residue is part of a larger polysaccharide chain.	tmpzr1t_l9r_go_relaxed.owl	PvGal metabolic process|4-6-O-[(R)(1-carboxyethylidine)]-Gal-beta-1,3 metabolism|4,6-pyruvylated galactose residue metabolism|PvGal metabolism|4-6-O-[(R)(1-carboxyethylidine)]-Gal-beta-1,3 metabolic process													biological_process											owl:Class	
GO:0004176	biolink:NamedThing	ATP-dependent peptidase activity	Catalysis of the hydrolysis of peptide bonds, driven by ATP hydrolysis.	tmpzr1t_l9r_go_relaxed.owl	ATP-dependent proteolysis	https://github.com/geneontology/go-ontology/issues/21612			Reactome:R-HSA-9698929							GO:0004280		molecular_function											owl:Class	
GO:0004760	biolink:NamedThing	serine-pyruvate transaminase activity	Catalysis of the reaction: L-serine + pyruvate = 3-hydroxypyruvate + L-alanine.	tmpzr1t_l9r_go_relaxed.owl	hydroxypyruvate:L-alanine transaminase activity|serine-pyruvate aminotransferase, type 2B|serine-pyruvate aminotransferase activity|L-serine:pyruvate aminotransferase activity|serine-pyruvate aminotransferase, type 1|serine--pyruvate aminotransferase activity|SPT|serine-pyruvate aminotransferase, type 2A				KEGG_REACTION:R00585|EC:2.6.1.51|MetaCyc:SERINE--PYRUVATE-AMINOTRANSFERASE-RXN|RHEA:22852							GO:0004762|GO:0004763|GO:0004761		molecular_function											owl:Class	
GO:0031477	biolink:NamedThing	myosin VII complex	A myosin complex containing a dimer of class VII myosin heavy chains and associated light chains. Myosin VII (240 kDa) is predicted to be a dimeric molecule with 5 IQ motifs and a tail region with a short stretch of coiled coil followed by two myosin-tail homology (MyTH4) domains, two talin-binding (FERM) domains and an SH3-domain.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:1904379	biolink:NamedThing	protein localization to cytosolic proteasome complex involved in ERAD pathway	Any protein localization to cytosolic proteasome complex that is involved in ERAD pathway. Following their retrotranslocation out of the endoplasmic reticulum, protein substrates must be shuttled to the cytosolic proteasome for degradation.	tmpzr1t_l9r_go_relaxed.owl	protein localization to cytosolic proteasome complex involved in endoplasmic reticulum-associated degradation|protein localization to cytosolic proteasome complex involved in endoplasmic reticulum-associated protein degradation pathway|protein localisation to cytosolic proteasome complex involved in ER-associated degradation pathway|protein localization in cytosolic proteasome complex involved in endoplasmic reticulum-associated protein degradation pathway|protein localisation in cytosolic proteasome complex involved in ER-associated degradation pathway|protein localisation to cytosolic proteasome complex involved in ERAD pathway|protein localisation in cytosolic proteasome complex involved in endoplasmic reticulum-associated degradation|protein localisation in cytosolic proteasome complex involved in endoplasmic reticulum-associated protein degradation pathway|protein localization in cytosolic proteasome complex involved in endoplasmic reticulum-associated degradation|protein localization to cytosolic proteasome complex involved in ER-associated degradation pathway|protein localisation to cytosolic proteasome complex involved in endoplasmic reticulum-associated degradation|protein localisation in cytosolic proteasome complex involved in ERAD pathway|protein localization in cytosolic proteasome complex involved in ERAD pathway|protein localisation to cytosolic proteasome complex involved in endoplasmic reticulum-associated protein degradation pathway|protein localization in cytosolic proteasome complex involved in ER-associated degradation pathway							bf	2015-06-23T09:30:07Z					biological_process											owl:Class	
GO:0015248	biolink:NamedThing	sterol transporter activity	Enables the directed movement of sterols into, out of or within a cell, or between cells. Sterol are steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-5250531|Reactome:R-HSA-8867667|RHEA:39747|Reactome:R-HSA-5679101|Reactome:R-HSA-5679145|Reactome:R-HSA-8868402|Reactome:R-HSA-265783									molecular_function											owl:Class	
GO:0140293	biolink:NamedThing	ADP-ribosylglutamate hydrolase activity	Catalysis of the reaction: (ADP-D-ribosyl)-L-glutamyl-[protein] + H2O = L-glutamyl-[protein] + ADP-ribose.	tmpzr1t_l9r_go_relaxed.owl								pg	2018-11-22T14:36:37Z					molecular_function											owl:Class	
GO:0039723	biolink:NamedThing	suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity	Any process in which a virus stops, prevents, or reduces a viral-induced cytoplasmic pattern recognition receptor signaling pathway in a host organism by reducing the activity of a host serine/threonine kinase TBK1.	tmpzr1t_l9r_go_relaxed.owl	inhibition of host TBK1 by virus|suppression by virus of host TBK1 activity	https://github.com/geneontology/go-ontology/issues/21970						bf	2014-01-06T12:04:44Z					biological_process											owl:Class	
GO:2000309	biolink:NamedThing	positive regulation of tumor necrosis factor (ligand) superfamily member 11 production	Any process that activates or increases the frequency, rate or extent of tumor necrosis factor (ligand) superfamily member 11 production.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of TNFSF11 production|positive regulation of RANKL production							mah	2011-01-17T10:44:54Z					biological_process											owl:Class	
GO:0035165	biolink:NamedThing	embryonic crystal cell differentiation	The process in which an embryonic mesoderm-derived hemocyte precursor cell acquires the specialized features of a crystal cell. Crystal cells are a class of cells that contain crystalline inclusions and are involved in the melanization of pathogenic material in the hemolymph.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0042707	biolink:NamedThing	ocellus photoreceptor cell fate commitment	The process in which the developmental fate of a cell becomes restricted such that it will develop into photoreceptor cell in the ocellus. A photoreceptor cell is a cell that responds to incident electromagnetic radiation. Different classes of photoreceptor have different spectral sensitivities and express different photosensitive pigments.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0120139	biolink:NamedThing	positive regulation of phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity	Any process that activates or increases the frequency, rate or extent of phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity.	tmpzr1t_l9r_go_relaxed.owl								krc	2018-03-22T16:24:20Z					biological_process											owl:Class	
GO:0061395	biolink:NamedThing	positive regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance	Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of an arsenic stimulus from compounds containing arsenic, including arsenates, arsenites, and arsenides.	tmpzr1t_l9r_go_relaxed.owl								dph	2011-12-14T08:53:20Z					biological_process											owl:Class	
GO:0061394	biolink:NamedThing	regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance	Modulation of the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of an arsenic stimulus from compounds containing arsenic, including arsenates, arsenites, and arsenides.	tmpzr1t_l9r_go_relaxed.owl								dph	2011-12-14T08:48:36Z					biological_process											owl:Class	
GO:0030600	biolink:NamedThing	feruloyl esterase activity	Catalysis of the reaction: feruloyl-polysaccharide + H2O = ferulate + polysaccharide.	tmpzr1t_l9r_go_relaxed.owl	hydroxycinnamoyl esterase activity|hemicellulase accessory|cinnamoyl ester hydrolase activity|FAE-III|FAEA|ferulic acid esterase activity|cinnAE|FAE-II|4-hydroxy-3-methoxycinnamoyl-sugar hydrolase activity|FAE-I				MetaCyc:3.1.1.73-RXN|EC:3.1.1.73									molecular_function											owl:Class	
GO:0050419	biolink:NamedThing	hydroxymandelonitrile lyase activity	Catalysis of the reaction: 4-hydroxymandelonitrile = 4-hydroxybenzaldehyde + hydrocyanate.	tmpzr1t_l9r_go_relaxed.owl	sorghum hydroxynitrile lyase activity|hydroxynitrile lyase activity|(S)-4-hydroxymandelonitrile hydroxybenzaldehyde-lyase activity|(S)-4-hydroxymandelonitrile 4-hydroxybenzaldehyde-lyase (cyanide-forming)				EC:4.1.2.11|RHEA:15977|MetaCyc:HYDROXYMANDELONITRILE-LYASE-RXN									molecular_function											owl:Class	
GO:0018547	biolink:NamedThing	nitroglycerin reductase activity	Catalysis of the removal of one or more nitrite (NO2-) groups from nitroglycerin or a derivative.	tmpzr1t_l9r_go_relaxed.owl	NG reductase activity				UM-BBD_enzymeID:e0038									molecular_function											owl:Class	
GO:0060067	biolink:NamedThing	cervix development	The reproductive developmental process whose specific outcome is the progression of the cervix over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl	Mullerian tract development													biological_process											owl:Class	
GO:0036053	biolink:NamedThing	glomerular endothelium fenestra	A large plasma membrane-lined circular pore that perforates the flattened glomerular endothelium and, unlike those of other fenestrated capillaries, is not spanned by diaphragms; the density and size of glomerular fenestrae account, at least in part, for the high permeability of the glomerular capillary wall to water and small solutes.	tmpzr1t_l9r_go_relaxed.owl	glomerular endothelial cell fenestration|GEnC fenestration							bf	2011-12-12T10:53:24Z					cellular_component											owl:Class	
GO:0050573	biolink:NamedThing	dTDP-4-dehydro-6-deoxyglucose reductase activity	Catalysis of the reaction: dTDP-D-fucose + NADP(+) = dTDP-4-dehydro-6-deoxy-alpha-D-glucose + H(+) + NADPH.	tmpzr1t_l9r_go_relaxed.owl	dTDP-D-fucose:NADP+ oxidoreductase activity|dTDP-4-keto-6-deoxyglucose reductase activity				RHEA:36583|EC:1.1.1.266|MetaCyc:1.1.1.266-RXN|KEGG_REACTION:R05687									molecular_function											owl:Class	
GO:0004038	biolink:NamedThing	allantoinase activity	Catalysis of the reaction: allantoin + H2O = allantoate.	tmpzr1t_l9r_go_relaxed.owl	(S)-allantoin amidohydrolase activity				MetaCyc:ALLANTOINASE-RXN|RHEA:17029|EC:3.5.2.5									molecular_function											owl:Class	
GO:0043854	biolink:NamedThing	cyclic nucleotide-gated mechanosensitive ion channel activity	Enables the transmembrane transfer of an ion by a channel that opens in response to a mechanical stress and when a cyclic nucleotide has been bound by the channel complex or one of its constituent parts.	tmpzr1t_l9r_go_relaxed.owl	cyclic nucleotide-regulated mechanosensitive ion channel|cyclic nucleotide regulated mechanosensitive ion channel|cyclic nucleotide gated mechanosensitive ion channel activity|MscS|small conductance mechanosensitive ion channel|cyclic nucleotide-regulated small mechanosensitive ion channel													molecular_function											owl:Class	
GO:0047176	biolink:NamedThing	beta-glucogallin-tetrakisgalloylglucose O-galloyltransferase activity	Catalysis of the reaction: 1,2,3,6-tetrakis-O-galloyl-beta-D-glucose + 1-O-galloyl-beta-D-glucose = 1,2,3,4,6-pentakis-O-galloyl-beta-D-glucose + D-glucose.	tmpzr1t_l9r_go_relaxed.owl	beta-glucogallin:1,2,3,6-tetra-O-galloyl-beta-D-glucose 4-O-galloyltransferase activity|beta-glucogallin-tetragalloylglucose 4-galloyltransferase activity|beta-glucogallin:1,2,3,6-tetra-O-galloylglucose 4-O-galloyltransferase activity|1-O-galloyl-beta-D-glucose:1,2,3,6-tetrakis-O-galloyl-beta-D-glucose 4-O-galloyltransferase activity				KEGG_REACTION:R04498|EC:2.3.1.143|MetaCyc:2.3.1.143-RXN|RHEA:19109									molecular_function											owl:Class	
GO:0080007	biolink:NamedThing	S-nitrosoglutathione reductase activity	Catalysis of the reaction: glutathione N-hydroxysulfenamide + NADH + H+ = S-nitrosoglutathione + NAD+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-10742									molecular_function											owl:Class	
GO:1904391	biolink:NamedThing	response to ciliary neurotrophic factor	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ciliary neurotrophic factor stimulus.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-06-23T19:13:04Z					biological_process											owl:Class	
GO:0016805	biolink:NamedThing	dipeptidase activity	Catalysis of the hydrolysis of a dipeptide.	tmpzr1t_l9r_go_relaxed.owl	cytosolic dipeptidase activity				Reactome:R-HSA-5693783|Reactome:R-HSA-9026771|EC:3.4.13.-|Reactome:R-HSA-5433067|Reactome:R-HSA-266012							GO:0102008		molecular_function											owl:Class	
GO:1905199	biolink:NamedThing	manchette disassembly	The disaggregation of a manchette into its constituent components.	tmpzr1t_l9r_go_relaxed.owl								krc	2016-05-12T15:19:16Z					biological_process											owl:Class	
GO:0004017	biolink:NamedThing	adenylate kinase activity	Catalysis of the reaction: ATP + AMP = 2 ADP.	tmpzr1t_l9r_go_relaxed.owl	myokinase activity|ATP:AMP phosphotransferase activity|adenylokinase activity|adenylic kinase activity|5'-AMP-kinase activity				Reactome:R-HSA-110141|RHEA:12973|Reactome:R-HSA-74220|MetaCyc:ADENYL-KIN-RXN|Reactome:R-HSA-110144|Reactome:R-HSA-110145|EC:2.7.4.3									molecular_function											owl:Class	
GO:0035061	biolink:NamedThing	interchromatin granule	A class of nuclear body measuring 20-25 nm in diameter and distributed throughout the interchromatin space, linked together by thin fibrils. They are believed to be storage centers for various snRNAs, snRNPs, serine/arginine-rich proteins and RNA polymerase II. A typical mammalian cell contains 25-50 clusters of interchromatin granules. Interchromatin granule clusters do not contain the heterogeneous nuclear RNA-binding proteins (hnRNPs).	tmpzr1t_l9r_go_relaxed.owl	ICG				NIF_Subcellular:sao1049471211									cellular_component											owl:Class	
GO:0045439	biolink:NamedThing	isopenicillin-N epimerase activity	Catalysis of the reaction: isopenicillin N = penicillin N.	tmpzr1t_l9r_go_relaxed.owl	penicillin-N 5-amino-5-carboxypentanoyl-epimerase activity|isopenicillin N epimerase activity				EC:5.1.1.17|KEGG_REACTION:R04147|RHEA:20033|MetaCyc:5.1.1.17-RXN									molecular_function											owl:Class	
GO:1901492	biolink:NamedThing	positive regulation of lymphangiogenesis	Any process that activates or increases the frequency, rate or extent of lymphangiogenesis.	tmpzr1t_l9r_go_relaxed.owl	upregulation of lymphangiogenesis|positive regulation of lymph vessel formation|up regulation of lymph vessel formation|activation of lymph vessel formation|activation of lymphangiogenesis|up regulation of lymphangiogenesis|up-regulation of lymph vessel formation|upregulation of lymph vessel formation|up-regulation of lymphangiogenesis							dph	2012-10-15T13:08:25Z					biological_process											owl:Class	
GO:0044864	biolink:NamedThing	positive regulation by virus of host cell division	Any process where an infecting virus activates or increases the frequency, rate or extent of its host's cell division.	tmpzr1t_l9r_go_relaxed.owl								jl	2014-08-05T16:31:20Z					biological_process											owl:Class	
GO:0034564	biolink:NamedThing	4,4'-dihydroxy-alpha-methylstilbene dioxygenase activity	Catalysis of the reaction: 4,4'-dihydroxy-alpha-methylstilbene + O2 = 4-hydroxybenzaldehyde + 4-hydroxyacetophenone + 2 H+ + 2 e-.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0866									molecular_function											owl:Class	
GO:0042809	biolink:NamedThing	vitamin D receptor binding	Binding to a vitamin D receptor, a nuclear receptor that mediates the action of vitamin D by binding DNA and controlling the transcription of hormone-sensitive genes.	tmpzr1t_l9r_go_relaxed.owl	VDR binding|calciferol receptor binding													molecular_function											owl:Class	
GO:0097418	biolink:NamedThing	neurofibrillary tangle	Intracellular mass of paired, helically wound protein filaments (also called PHF) lying in the cytoplasm of neuronal cell bodies and neuritic cell processes. Neurofibrillary tangles contain an abnormally phosphorylated form of a microtubule-associated protein, tau. The shape of these inclusions may resemble a flame or a star.	tmpzr1t_l9r_go_relaxed.owl	flame-shaped neurofibrillary tangle|star-shaped neurofibrillary tangle				NIF_Subcellular:nlx_subcell_20090202|NIF_Subcellular:sao2409833926|NIF_Subcellular:nlx_subcell_20090201	Neurofibrillary tangles have been found in aging population; their formation is increased in Alzheimer's disease patients (and in other neurological diseases) compared to normal controls (see PMID:848276 and PMID:8584267).		pr	2012-11-06T16:49:35Z					cellular_component											owl:Class	
GO:0033981	biolink:NamedThing	D-dopachrome decarboxylase activity	Catalysis of the reaction: D-dopachrome + H(+) = 5,6-dihydroxyindole + CO(2).	tmpzr1t_l9r_go_relaxed.owl	D-dopachrome carboxy-lyase activity|phenylpyruvate tautomerase II activity|dopachrome conversion activity|D-dopachrome tautomerase activity|D-dopachrome carboxy-lyase (5,6-dihydroxyindole-forming) activity|dopachrome decarboxylase activity|D-tautomerase activity				KEGG_REACTION:R07313|MetaCyc:4.1.1.84-RXN|RHEA:18441|EC:4.1.1.84							GO:0030928		molecular_function											owl:Class	
GO:1905466	biolink:NamedThing	negative regulation of G-quadruplex DNA unwinding	Any process that stops, prevents or reduces the frequency, rate or extent of G-quadruplex DNA unwinding.	tmpzr1t_l9r_go_relaxed.owl	down regulation of G-quadruplex DNA unwinding|downregulation of G-quadruplex DNA unwinding|inhibition of G-quadruplex DNA unwinding|down-regulation of G-quadruplex DNA unwinding							ans	2016-09-19T12:15:53Z					biological_process											owl:Class	
GO:0099089	biolink:NamedThing	establishment of endoplasmic reticulum localization to postsynapse	The directed movement of endoplasmic reticulum into a postsynaptic compartment such as a dendritic spine.	tmpzr1t_l9r_go_relaxed.owl	establishment of ER localization to postsynapse													biological_process											owl:Class	
GO:1904645	biolink:NamedThing	response to amyloid-beta	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a amyloid-beta stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to beta-amyloid|response to beta-amyloids							sl	2015-08-31T20:44:43Z					biological_process											owl:Class	
GO:0010298	biolink:NamedThing	dihydrocamalexic acid decarboxylase activity	Catalysis of the reaction: dihydrocamalexic acid = camalexin + CO2 + H+.	tmpzr1t_l9r_go_relaxed.owl					RHEA:34807|MetaCyc:RXN-8275									molecular_function											owl:Class	
GO:1903229	biolink:NamedThing	xanthosine biosynthetic process	The chemical reactions and pathways resulting in the formation of xanthosine.	tmpzr1t_l9r_go_relaxed.owl	xanthosine anabolism|xanthosine synthesis|xanthosine biosynthesis|xanthosine formation							jl	2014-07-31T09:21:58Z					biological_process											owl:Class	
GO:0033737	biolink:NamedThing	1-pyrroline dehydrogenase activity	Catalysis of the reaction: 1-pyrroline + NAD+ + 2 H2O = 4-aminobutanoate + NADH + 2 H+.	tmpzr1t_l9r_go_relaxed.owl	1-pyrroline:NAD+ oxidoreductase activity|YdcW|ABALDH|gamma-aminobutyraldehyde dehydrogenase activity				MetaCyc:1.5.1.35-RXN|EC:1.2.1.19									molecular_function											owl:Class	
GO:0036436	biolink:NamedThing	Isw1a complex	An Isw1 complex that binds DNA and has nucleosome-stimulated ATPase activity. In S. cerevisiae, contains an Isw1p ATPase subunit in complex with Ioc3p.	tmpzr1t_l9r_go_relaxed.owl								bf	2013-09-18T16:45:41Z					cellular_component											owl:Class	
GO:0016587	biolink:NamedThing	Isw1 complex	A protein complex that contains an Isw1 subunit from the ISWI-family of ATPases and acts to modify chromatin structure.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0099150	biolink:NamedThing	regulation of postsynaptic specialization assembly	Any process that modulates the frequency, rate or extent of postsynaptic specialization assembly, the aggregation, arrangement and bonding together of a set of components to form a postsynaptic specialization.	tmpzr1t_l9r_go_relaxed.owl								dos	2017-07-05T13:20:48Z					biological_process											owl:Class	
GO:0090204	biolink:NamedThing	protein localization to nuclear pore	A process in which a protein is transported to, or maintained in, a nuclear pore.	tmpzr1t_l9r_go_relaxed.owl	protein localisation to nuclear pore							tb	2009-12-18T12:05:01Z					biological_process											owl:Class	
GO:0043203	biolink:NamedThing	axon hillock	Portion of the neuronal cell soma from which the axon originates.	tmpzr1t_l9r_go_relaxed.owl					NIF_Subcellular:sao627227260|Wikipedia:Axon_hillock									cellular_component											owl:Class	
GO:0070386	biolink:NamedThing	procollagen-proline 4-dioxygenase complex, alpha(I) type	A procollagen-proline 4-dioxygenase complex that contains alpha subunits of the type I isoform; its activity is readily inhibited by poly(L-proline).	tmpzr1t_l9r_go_relaxed.owl	prolyl 4-hydroxylase complex (alpha(I)-type)|procollagen-proline, 2-oxoglutarate-4-dioxygenase complex, alpha(I) type													cellular_component											owl:Class	
GO:0071076	biolink:NamedThing	RNA 3' uridylation	The enzymatic addition of a sequence of uridylyl residues at the 3' end of an RNA molecule.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-11-06T02:41:23Z					biological_process											owl:Class	
GO:0043489	biolink:NamedThing	RNA stabilization	Prevention of degradation of RNA molecules.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0120212	biolink:NamedThing	sperm head-tail coupling apparatus	A centrosome-based structure consisting of two cylindrical microtubule-based centrioles and associated components which anchors the flagellum to the sperm head.	tmpzr1t_l9r_go_relaxed.owl	HTCA|head-tail coupling apparatus							krc	2019-06-07T23:08:46Z					cellular_component											owl:Class	
GO:1905225	biolink:NamedThing	response to thyrotropin-releasing hormone	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a thyrotropin-releasing hormone (TRH) stimulus. TRH increases the secretion of thyroid-stimulating hormone by the anterior pituitary.	tmpzr1t_l9r_go_relaxed.owl	response to TRH|response to protirelin							pr	2016-06-07T12:11:28Z					biological_process											owl:Class	
GO:0047243	biolink:NamedThing	flavanone 7-O-beta-glucosyltransferase activity	Catalysis of the reaction: a flavanone + UDP-D-glucose = a flavanone 7-O-beta-D-glucoside + UDP.	tmpzr1t_l9r_go_relaxed.owl	uridine diphosphoglucose-flavanone 7-O-glucosyltransferase activity|naringenin 7-O-glucosyltransferase activity|hesperetin 7-O-glucosyl-transferase activity|UDP-glucose:flavanone 7-O-beta-D-glucosyltransferase activity|UDPglucose:flavanone 7-O-beta-D-glucosyltransferase activity				MetaCyc:2.4.1.185-RXN|EC:2.4.1.185									molecular_function											owl:Class	
GO:0047588	biolink:NamedThing	5-aminopentanamidase activity	Catalysis of the reaction: 5-aminopentanamide + H2O = 5-aminopentanoate + NH3.	tmpzr1t_l9r_go_relaxed.owl	5-aminopentanamide amidohydrolase activity|5-aminovaleramidase activity|5-aminonorvaleramidase activity				MetaCyc:5-AMINOPENTANAMIDASE-RXN|RHEA:15677|EC:3.5.1.30									molecular_function											owl:Class	
GO:0072715	biolink:NamedThing	cellular response to selenite ion	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a selenite ion stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2012-04-19T02:47:50Z					biological_process											owl:Class	
GO:0030755	biolink:NamedThing	quercetin 3-O-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + 3,5,7,3',4'-pentahydroxyflavone = S-adenosyl-L-homocysteine + 3-methoxy-5,7,3',4'-tetrahydroxy-flavone.	tmpzr1t_l9r_go_relaxed.owl	flavonoid 3-methyltransferase activity|S-adenosyl-L-methionine:3,5,7,3',4'-pentahydroxyflavone 3-O-methyltransferase activity|flavonol 3-O-methyltransferase activity				EC:2.1.1.76|RHEA:17673|MetaCyc:QUERCETIN-3-O-METHYLTRANSFERASE-RXN									molecular_function											owl:Class	
GO:0032296	biolink:NamedThing	double-stranded RNA-specific ribonuclease activity	Catalysis of the hydrolysis of phosphodiester bonds in double-stranded RNA molecules.	tmpzr1t_l9r_go_relaxed.owl	dsRNA-specific RNase activity|double-stranded RNA-specific RNase activity|dsRNA-specific ribonuclease activity													molecular_function											owl:Class	
GO:0102444	biolink:NamedThing	isorhamnetin 3-O-methyltransferase activity	Catalysis of the reaction: isorhamnetin + S-adenosyl-L-methionine  <=> 3,3'-dimethylquercetin + S-adenosyl-L-homocysteine.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-13929									molecular_function											owl:Class	
GO:0120249	biolink:NamedThing	lateral wall of outer hair cell	The lateral wall of an outer hair cell (OHC) is a unique trilaminate composite consisting of the plasma membrane, an underlying cytoskeletal network containing an actin-spectrin cortical lattice, and an adjacent system of circumferential lamellar organelles known as the subsurface cisternae.	tmpzr1t_l9r_go_relaxed.owl	outer hair cell lateral wall|OHC lateral wall|lateral wall of OHC							krc	2020-08-27T23:53:44Z					cellular_component											owl:Class	
GO:0102116	biolink:NamedThing	laurate hydroxylase activity	Catalysis of the reaction: dodecanoate + NADPH + O2 + H+ <=> 11-hydroxylaurate + NADP + H2O.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-11340									molecular_function											owl:Class	
GO:0031423	biolink:NamedThing	hexon binding	Binding to a hexon, the major protein component of the icosahedral capsid of an adenovirus.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0004110	biolink:NamedThing	corticosteroid side-chain-isomerase activity	Catalysis of the reaction: 11-deoxycorticosterone = 20-hydroxy-3-oxopregn-4-en-21-al.	tmpzr1t_l9r_go_relaxed.owl	11-deoxycorticosterone aldose-ketose-isomerase activity|11-deoxycorticosterone ketol-isomerase activity				EC:5.3.1.21|KEGG_REACTION:R04165|RHEA:17861|MetaCyc:CORTICOSTEROID-SIDE-CHAIN-ISOMERASE-RXN									molecular_function											owl:Class	
GO:0034569	biolink:NamedThing	monodemethylisoproturon dehydrogenase activity	Catalysis of the reaction: monodemethylisoproturon + H2O = hydroxymonodemethylisoproturon + 2 H+ + 2 e-.	tmpzr1t_l9r_go_relaxed.owl					EC:1.17.99.-|UM-BBD_reactionID:r0893									molecular_function											owl:Class	
GO:0032044	biolink:NamedThing	DSIF complex	A heterodimeric protein complex formed of Spt4 and Spt5 proteins which is expressed in eukaryotes from yeast to man. DSIF is an inhibitory elongation factor that promotes RNA polymerase II transcriptional pausing, but can also stimulate transcriptional elongation under certain conditions, and may play a role in RNA processing via its physical association with mRNA capping enzymes.	tmpzr1t_l9r_go_relaxed.owl	DRB sensitivity inducing factor complex|5,6-Dichloro-1-beta-D-ribofuranosylbenzimidazole sensitivity inducing factor complex|Spt5-Spt4 complex|Spt4-Spt5 complex													cellular_component											owl:Class	
GO:0031698	biolink:NamedThing	beta-2 adrenergic receptor binding	Binding to a beta-2 adrenergic receptor.	tmpzr1t_l9r_go_relaxed.owl	beta-2 adrenergic receptor ligand													molecular_function											owl:Class	
GO:0055068	biolink:NamedThing	cobalt ion homeostasis	Any process involved in the maintenance of an internal steady state of cobalt ions within an organism or cell.	tmpzr1t_l9r_go_relaxed.owl	cobalt homeostasis													biological_process											owl:Class	
GO:0003985	biolink:NamedThing	acetyl-CoA C-acetyltransferase activity	Catalysis of the reaction: 2 acetyl-CoA = CoA + acetoacetyl-CoA.	tmpzr1t_l9r_go_relaxed.owl	2-methylacetoacetyl-CoA thiolase|acetyl coenzyme A thiolase activity|acetoacetyl-CoA thiolase activity|thiolase II|3-oxothiolase activity|acetyl-CoA:acetyl-CoA C-acetyltransferase activity|acetyl-CoA acetyltransferase activity|beta-acetoacetyl coenzyme A thiolase activity|acetyl-CoA:N-acetyltransferase activity				Reactome:R-HSA-70844|Reactome:R-HSA-8848215|UM-BBD_enzymeID:e0144|RHEA:21036|EC:2.3.1.9|MetaCyc:ACETYL-COA-ACETYLTRANSFER-RXN|Reactome:R-HSA-73916|Reactome:R-HSA-74181									molecular_function											owl:Class	
GO:0003988	biolink:NamedThing	acetyl-CoA C-acyltransferase activity	Catalysis of the reaction: acyl-CoA + acetyl-CoA = CoA + 3-oxoacyl-CoA.	tmpzr1t_l9r_go_relaxed.owl	2-methylacetoacetyl-CoA thiolase|beta-ketothiolase activity|3-ketoacyl coenzyme A thiolase activity|ketoacyl-CoA acyltransferase activity|ketoacyl-coenzyme A thiolase activity|pro-3-ketoacyl-CoA thiolase activity|beta-ketoacyl-CoA thiolase activity|3-ketoacyl CoA thiolase activity|2-keto-acyl thiolase activity|KAT|acyl-CoA:acetyl-CoA C-acyltransferase activity|3-ketoacyl thiolase activity|beta-ketoadipyl coenzyme A thiolase activity|3-ketothiolase activity|beta-ketoacyl coenzyme A thiolase activity|6-oxoacyl-CoA thiolase activity|acetyl-CoA acyltransferase activity|3-oxoacyl-coenzyme A thiolase activity|thiolase I|long-chain 3-oxoacyl-CoA thiolase activity|oxoacyl-coenzyme A thiolase activity|3-ketoacyl-CoA thiolase activity|3-oxoacyl-CoA thiolase activity|acetoacetyl-CoA beta-ketothiolase activity|beta-ketoadipyl-CoA thiolase activity				EC:2.3.1.16|UM-BBD_reactionID:r1051|Reactome:R-HSA-390250|Reactome:R-HSA-77271|MetaCyc:KETOACYLCOATHIOL-RXN|Reactome:R-HSA-77304|Reactome:R-HSA-77329|Reactome:R-HSA-8874745|Reactome:R-HSA-77340|Reactome:R-HSA-77321|RHEA:21564|Reactome:R-HSA-77309									molecular_function											owl:Class	
GO:1990195	biolink:NamedThing	macrolide transmembrane transporter complex	A bacterial transmembrane transporter complex that spans the entire cell membrane system and possesses ATP-dependent xenobiotic transport activity pumping drugs (typically antibiotics) and other toxins directly from the cytosol out of the bacterial cell. Typically, it is trimeric consisting of a inner membrane ATPase (IMP), a periplasmic membrane fusion protein (MFP) and an outer membrane factor (OMF). In E. coli, macrolide transporter complexes may consists of MacB (IMP), MacA (MFP) and TolC (OMF) or AcrB (IMP), AcrA (MFP) and TolC (OMF). Trimeric TolC is a common OMF found in many macrolide transporter complexes.	tmpzr1t_l9r_go_relaxed.owl	AcrAB-TolC complex|MacAB-TolC complex|macrolide transporter|macrolide transporter complex							bhm	2013-09-23T11:22:26Z					cellular_component											owl:Class	
GO:0016401	biolink:NamedThing	palmitoyl-CoA oxidase activity	Catalysis of the reaction: palmitoyl-CoA + O2 = trans-2,3-dehydropalmitoyl-CoA + hydrogen peroxide.	tmpzr1t_l9r_go_relaxed.owl					EC:1.3.3.-									molecular_function											owl:Class	
GO:0038063	biolink:NamedThing	collagen-activated tyrosine kinase receptor signaling pathway	A series of molecular signals initiated by the binding of collagen to a receptor on the surface of the target cell where the receptor possesses tyrosine kinase activity. The pathway ends with regulation of a downstream cellular process, e.g. transcription.	tmpzr1t_l9r_go_relaxed.owl	collagen-activated RTK signaling pathway|DDR signaling pathway|discoidin domain receptor signaling pathway|collagen-activated tyrosine kinase receptor signalling pathway							bf	2012-01-18T01:43:20Z					biological_process											owl:Class	
GO:1903600	biolink:NamedThing	glutaminase complex	A protein complex which is capable of glutaminase activity.	tmpzr1t_l9r_go_relaxed.owl	Sno1p-Snz1p							ew	2014-11-11T18:41:42Z					cellular_component											owl:Class	
GO:0002930	biolink:NamedThing	trabecular meshwork development	The progression of the trabecular meshwork over time, from its formation to the mature structure. The trabecular meshwork is a fenestrated endothelial-like tissue situated at the intersection of the cornea and the iris. The trabecular meshwork provides drainage for the aqueous humor.	tmpzr1t_l9r_go_relaxed.owl								hjd	2012-04-19T04:50:06Z					biological_process											owl:Class	
GO:0070713	biolink:NamedThing	RNA guanosine-cytidine insertion	The modification of an RNA molecule by insertion of an guanosine-cytidine dinucleotide.	tmpzr1t_l9r_go_relaxed.owl	RNA GC insertion							mah	2009-06-08T05:31:43Z					biological_process											owl:Class	
GO:0071173	biolink:NamedThing	spindle assembly checkpoint signaling	A signaling process that delays the metaphase/anaphase transition until the spindle is correctly assembled and chromosomes are attached to the spindle.	tmpzr1t_l9r_go_relaxed.owl	signal transduction involved in spindle assembly checkpoint|SAC|spindle assembly checkpoint	https://github.com/geneontology/go-ontology/issues/20935				Note that this term should not be used for direct manual annotation as it should always be possible to specify the type of spindle assembly checkpoint (mitotic or meiotic).		mah	2009-11-23T12:36:57Z			GO:0072486		biological_process											owl:Class	
GO:0034454	biolink:NamedThing	microtubule anchoring at centrosome	Any process in which a microtubule is maintained in a specific location in a cell by attachment to a centrosome.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0060595	biolink:NamedThing	fibroblast growth factor receptor signaling pathway involved in mammary gland specification	The series of molecular signals initiated by binding of a fibroblast growth factor to its receptor on the surface of al cell in the epidermis resulting in the formation of the mammary line. The mammary line is a ridge of epidermal cells that will form the mammary placodes.	tmpzr1t_l9r_go_relaxed.owl	fibroblast growth factor receptor signalling pathway involved in mammary gland specification							dph	2009-05-13T10:38:18Z					biological_process											owl:Class	
GO:0050872	biolink:NamedThing	white fat cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a white adipocyte, an animal connective tissue cell involved in energy storage. White adipocytes have cytoplasmic lipids arranged in a unique vacuole.	tmpzr1t_l9r_go_relaxed.owl	white adipocyte cell differentiation|white adipocyte differentiation													biological_process											owl:Class	
GO:0031740	biolink:NamedThing	type A cholecystokinin receptor binding	Binding to a type A cholecystokinin receptor.	tmpzr1t_l9r_go_relaxed.owl	type A cholecystokinin receptor ligand													molecular_function											owl:Class	
GO:0051874	biolink:NamedThing	sphinganine-1-phosphate catabolic process	The chemical reactions and pathways resulting in the breakdown of sphinganine-1-phosphate, the phosphorylated derivative of D-erythro-2-amino-1,3-octadecanediol.	tmpzr1t_l9r_go_relaxed.owl	dihydrosphingosine-1-phosphate catabolic process|dihydrosphingosine-1-phosphate catabolism													biological_process											owl:Class	
GO:0072225	biolink:NamedThing	metanephric late distal convoluted tubule development	The process whose specific outcome is the progression of the metanephric late distal convoluted tubule over time, from its formation to the mature structure. The metanephric late distal convoluted tubule contains metanephric DCT cells and intercalated (IC) alpha and beta cells and is vasopressin-sensitive.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-03-18T03:37:04Z					biological_process											owl:Class	
GO:0043328	biolink:NamedThing	protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway	The process of directing proteins towards the vacuole that contributes to protein catabolism via the multivesicular body (MVB) pathway.	tmpzr1t_l9r_go_relaxed.owl	protein targeting to vacuole during ubiquitin-dependent protein degradation via the MVB pathway|protein targeting to vacuole during ubiquitin-dependent protein breakdown via the MVB pathway|protein-vacuole targeting during ubiquitin-dependent protein catabolic process via the MVB pathway|protein vacuolar targeting during ubiquitin-dependent protein catabolism via the MVB pathway|protein-vacuole targeting during ubiquitin-dependent protein catabolism via the MVB pathway|protein-vacuolar targeting during ubiquitin-dependent protein degradation via the MVB pathway|protein targeting to vacuole during ubiquitin-dependent protein catabolic process via the MVB pathway|protein vacuolar targeting during ubiquitin-dependent protein catabolic process via the MVB pathway|protein-vacuolar targeting during ubiquitin-dependent protein breakdown via the MVB pathway													biological_process											owl:Class	
GO:0004399	biolink:NamedThing	histidinol dehydrogenase activity	Catalysis of the reaction: L-histidinol + NAD+ = L-histidine + NADH + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:HISTOLDEHYD-RXN|RHEA:20641|MetaCyc:HISTALDEHYD-RXN|EC:1.1.1.23									molecular_function											owl:Class	
GO:0008672	biolink:NamedThing	2-dehydro-3-deoxyglucarate aldolase activity	Catalysis of the reaction: 2-dehydro-3-deoxy-D-glucarate = pyruvate + tartronate semialdehyde.	tmpzr1t_l9r_go_relaxed.owl	2-dehydro-3-deoxy-D-glucarate tartronate-semialdehyde-lyase (pyruvate-forming)|alpha-keto-beta-deoxy-D-glucarate aldolase activity|2-dehydro-3-deoxy-D-glucarate tartronate-semialdehyde-lyase activity|2-keto-3-deoxyglucarate aldolase activity				EC:4.1.2.20|RHEA:10268|MetaCyc:KDGALDOL-RXN									molecular_function											owl:Class	
GO:0045505	biolink:NamedThing	dynein intermediate chain binding	Binding to an intermediate chain of the dynein complex.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0033866	biolink:NamedThing	nucleoside bisphosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of a nucleoside bisphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar.	tmpzr1t_l9r_go_relaxed.owl	nucleoside bisphosphate formation|nucleoside bisphosphate anabolism|nucleoside bisphosphatehate synthesis|nucleoside bisphosphate biosynthesis													biological_process											owl:Class	
GO:0102109	biolink:NamedThing	tricaffeoyl spermidine O-methyltransferase activity	Catalysis of the reaction: tricaffeoyl spermidine + 3 S-adenosyl-L-methionine  <=> 3 H+ + triferuloyl spermidine + 3 S-adenosyl-L-homocysteine.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-11261									molecular_function											owl:Class	
GO:0048877	biolink:NamedThing	homeostasis of number of retina cells	Any biological process involved in the maintenance of the steady-state number of cells within a population of cells in the retina.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0004740	biolink:NamedThing	pyruvate dehydrogenase (acetyl-transferring) kinase activity	Catalysis of the reaction: ATP + pyruvate dehydrogenase (acetyl-transferring) = ADP + pyruvate dehydrogenase (acetyl-transferring) phosphate.	tmpzr1t_l9r_go_relaxed.owl	PDH kinase activity|pyruvate dehydrogenase kinase activity|PDK|PDHK|pyruvate dehydrogenase kinase (phosphorylating) activity				Reactome:R-HSA-203946|RHEA:23052|EC:2.7.11.2|MetaCyc:2.7.11.2-RXN									molecular_function											owl:Class	
GO:0006710	biolink:NamedThing	androgen catabolic process	The chemical reactions and pathways resulting in the breakdown of androgens, C19 steroid hormones that can stimulate the development of male sexual characteristics.	tmpzr1t_l9r_go_relaxed.owl	androgen breakdown|androgen degradation|androgen catabolism													biological_process											owl:Class	
GO:0008209	biolink:NamedThing	androgen metabolic process	The chemical reactions and pathways involving androgens, C19 steroid hormones that can stimulate the development of male sexual characteristics.	tmpzr1t_l9r_go_relaxed.owl	androgen metabolism													biological_process											owl:Class	
GO:0060773	biolink:NamedThing	flower phyllotactic patterning	The radial pattern formation process that results in the formation of floral organ primordia around a central axis in a flower primordium.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-07-25T06:28:38Z					biological_process											owl:Class	
GO:0050495	biolink:NamedThing	peptidyl-glycyl-phosphatidylethanolamine biosynthetic process from peptidyl-glycine	The chemical reactions and pathways resulting in the formation of a C-terminal peptidyl-glycine ethanolamide-linked phosphatide following hydrolysis of a glycyl-peptide bond, as in the cleavage of arginine from the carboxy-terminal of Apg8 followed by its amidation with phosphatidylethanolamine.	tmpzr1t_l9r_go_relaxed.owl	peptidyl-glycyl-phosphatidylethanolamine anabolism from peptidyl-glycine|peptidyl-glycyl-phosphatidylethanolamine formation from peptidyl-glycine|peptidyl-glycyl-phosphatidylethanolamine synthesis from peptidyl-glycine				RESID:AA0346									biological_process											owl:Class	
GO:0008927	biolink:NamedThing	mannonate dehydratase activity	Catalysis of the reaction: D-mannonate = 2-dehydro-3-deoxy-D-gluconate + H(2)O.	tmpzr1t_l9r_go_relaxed.owl	altronate hydrolase activity|mannonate hydrolyase activity|mannonic hydrolase activity|D-mannonate hydro-lyase activity|D-mannonate hydrolyase activity|altronic hydro-lyase activity|D-mannonate hydro-lyase (2-dehydro-3-deoxy-D-gluconate-forming)				EC:4.2.1.8|RHEA:20097|KEGG_REACTION:R05606|MetaCyc:MANNONDEHYDRAT-RXN									molecular_function											owl:Class	
GO:0019470	biolink:NamedThing	4-hydroxyproline catabolic process	The chemical reactions and pathways resulting in the breakdown of 4-hydroxyproline, C5H9NO3, a derivative of the amino acid proline.	tmpzr1t_l9r_go_relaxed.owl	4-hydroxyproline degradation|4-hydroxyproline breakdown|4-hydroxyproline catabolism				MetaCyc:HYDROXYPRODEG-PWY									biological_process											owl:Class	
GO:0008707	biolink:NamedThing	4-phytase activity	Catalysis of the reaction: myo-inositol hexakisphosphate + H2O = 1-myo-inositol 1,2,3,4,5-pentakisphosphate + phosphate.	tmpzr1t_l9r_go_relaxed.owl	myo-inositol-hexakisphosphate 6-phosphohydrolase activity|phytase activity|phytate 6-phosphatase activity|6-phytase (name based on 1L-numbering system and not 1D-numbering)|6-phytase activity				MetaCyc:6-PHYT-RXN|RHEA:20960|EC:3.1.3.26									molecular_function											owl:Class	
GO:0018524	biolink:NamedThing	acetophenone carboxylase activity	Catalysis of the reaction: acetophenone + CO2 = H+ + benzoyl acetate.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0033|EC:6.4.1.-							GO:0018797		molecular_function											owl:Class	
GO:0019412	biolink:NamedThing	aerobic respiration, using hydrogen as electron donor	The oxidation of hydrogen (H2) to water (H2O), using oxygen (O2) as the electron acceptor. A hydrogenase enzyme binds H2 and the hydrogen atoms are passed through an electron transfer chain to O2 to form water.	tmpzr1t_l9r_go_relaxed.owl	hydrogen oxidation				MetaCyc:P283-PWY									biological_process											owl:Class	
GO:0008398	biolink:NamedThing	sterol 14-demethylase activity	Catalysis of the reaction: obtusifoliol + 3 O2 + 3 NADPH + 3 H+ = 4-alpha-methyl-5-alpha-ergosta-8,14,24(28)-trien-3-beta-ol + formate + 3 NADP+ + 3 H2O.	tmpzr1t_l9r_go_relaxed.owl	cytochrome P450 51 activity|lanosterol 14-alpha-demethylase activity|cytochrome P450 CYP51|sterol 14-alpha-demethylase activity|sterol 14alpha-demethylase activity|obtusufoliol 14-demethylase activity|sterol,NADPH:oxygen oxidoreductase (14-methyl cleaving)|lanosterol 14-demethylase activity|lanosterol 14alpha-demethylase activity				MetaCyc:1.14.13.70-RXN|Reactome:R-HSA-194678|EC:1.14.13.70|RHEA:14917									molecular_function											owl:Class	
GO:0034338	biolink:NamedThing	short-chain carboxylesterase activity	Catalysis of the reaction: a carboxylic ester + H2O = an alcohol + a carboxylic anion, where the carboxylic chain has 8 or fewer carbon atoms.	tmpzr1t_l9r_go_relaxed.owl	butyrate esterase activity|methylbutyrate esterase activity|propionyl esterase activity|short-chain esterase activity|monobutyrase activity|methylbutyrase activity|butyryl esterase activity													molecular_function											owl:Class	
GO:0102169	biolink:NamedThing	pyocyanin hydroxylase activity	Catalysis of the reaction: 5-methylphenazine-1-carboxylate + NADH + O2 + 2 H+ = pyocyanin + NAD + carbon dioxide + H2O.	tmpzr1t_l9r_go_relaxed.owl					EC:1.14.13.218|MetaCyc:RXN-11898|RHEA:48976									molecular_function											owl:Class	
GO:0102139	biolink:NamedThing	2-hydroxy-6-oxo-6-(2'-aminophenyl)-hexa-2,4dienoate hydrolase activity	Catalysis of the reaction: (2E,4E)-6-(2-aminophenyl)-2-hydroxy-6-oxohexa-2,4-dienoate + H2O <=> H+ + anthranilate + (2E)-2-hydroxypenta-2,4-dienoate.	tmpzr1t_l9r_go_relaxed.owl					RHEA:27870|EC:3.7.1.13|MetaCyc:RXN-11543									molecular_function											owl:Class	
GO:0000298	biolink:NamedThing	endopolyphosphatase activity	Catalysis of the reaction: polyphosphate + n H2O = (n+1) oligophosphate. The product contains 4 or 5 phosphate residues.	tmpzr1t_l9r_go_relaxed.owl	polymetaphosphatase activity|polyphosphate depolymerase activity|polyphosphate polyphosphohydrolase activity|metaphosphatase activity|polyphosphatase activity				MetaCyc:ENDOPOLYPHOSPHATASE-RXN|EC:3.6.1.10|RHEA:22452									molecular_function											owl:Class	
GO:0061701	biolink:NamedThing	bacterial outer membrane vesicle	A spherical, bilayered proteolipid vesicle released from gram-negative bacterial outer membranes.	tmpzr1t_l9r_go_relaxed.owl								dph	2015-05-07T13:53:47Z					cellular_component											owl:Class	
GO:0004810	biolink:NamedThing	tRNA adenylyltransferase activity	Catalysis of the reaction: ATP + tRNA(n) = diphosphate + tRNA(n+1).	tmpzr1t_l9r_go_relaxed.owl	transfer ribonucleic-terminal trinucleotide nucleotidyltransferase|transfer ribonucleic adenylyl (cytidylyl) transferase|CTP(ATP):tRNA nucleotidyltransferase|tRNA adenylyl(cytidylyl)transferase|-C-C-A pyrophosphorylase|ATP:tRNA adenylyltransferase activity|transfer ribonucleate nucleotidyltransferase|tRNA CCA-diphosphorylase activity|transfer-RNA nucleotidyltransferase|CCA-adding enzyme activity|ATP (CTP):tRNA nucleotidyltransferase|tRNA-nucleotidyltransferase activity|transfer ribonucleate adenyltransferase activity|transfer RNA adenylyltransferase|transfer ribonucleate adenylyltransferase|tRNA CCA-pyrophosphorylase activity|transfer ribonucleate cytidylyltransferase|ATP(CTP)-tRNA nucleotidyltransferase|transfer ribonucleic acid nucleotidyl transferase|ribonucleic cytidylyltransferase|ribonucleic cytidylic cytidylic adenylic pyrophosphorylase				MetaCyc:TRNA-ADENYLYLTRANSFERASE-RXN|EC:2.7.7.72									molecular_function											owl:Class	
GO:0018906	biolink:NamedThing	methyl tert-butyl ether metabolic process	The chemical reactions and pathways involving methyl tert-butyl ether, 2-methoxy-2-methylpropane. Methyl tert-butyl ether is a synthetic chemical which is mixed with gasoline for use in reformulated gasoline. It was first introduced as an additive for unleaded gasoline in the 1980s. It is also used as a laboratory reagent and a pharmaceutical agent.	tmpzr1t_l9r_go_relaxed.owl	methyl tert-butyl ether metabolism				UM-BBD_pathwayID:mtb									biological_process											owl:Class	
GO:0050074	biolink:NamedThing	malate-CoA ligase activity	Catalysis of the reaction: ATP + malate + CoA = ADP + phosphate + malyl-CoA.	tmpzr1t_l9r_go_relaxed.owl	malate:CoA ligase (ADP-forming)|malyl-CoA synthetase activity|malyl coenzyme A synthetase activity|malate thiokinase activity				EC:6.2.1.9|RHEA:26193|MetaCyc:MALATE--COA-LIGASE-RXN									molecular_function											owl:Class	
GO:0030631	biolink:NamedThing	pyrrolysine incorporation	The incorporation of pyrrolysine, also known as lysine methylamine methyltransferase cofactor adduct, into a peptide; uses a special tRNA that recognizes the UAG codon as a modified lysine, rather than as a termination codon. Pyrrolysine may be synthesized as a free amino acid or synthesized from a lysine charged tRNA before its incorporation; it is not a posttranslational modification of peptidyl-lysine; this modification is found in several Methanosarcina methylamine methyltransferases.	tmpzr1t_l9r_go_relaxed.owl	lysine methylamine methyltransferase cofactor adduct incorporation|monomethylamine methyltransferase cofactor lysine adduct incorporation				RESID:AA0321									biological_process											owl:Class	
GO:0045484	biolink:NamedThing	L-lysine 6-transaminase activity	Catalysis of the reaction: 2-oxoglutarate + L-lysine = L-glutamate + allysine.	tmpzr1t_l9r_go_relaxed.owl	L-lysine transaminase activity|lysine epsilon-aminotransferase activity|L-lysine aminotransferase activity|lysine 6-aminotransferase activity|L-lysine:2-oxoglutarate 6-aminotransferase activity|lysine:2-ketoglutarate 6-aminotransferase activity|L-lysine-alpha-ketoglutarate 6-aminotransferase activity|lysine epsilon-transaminase activity|L-lysine-alpha-ketoglutarate aminotransferase activity				KEGG_REACTION:R00457|MetaCyc:L-LYSINE-AMINOTRANSFERASE-RXN|RHEA:21200|EC:2.6.1.36									molecular_function											owl:Class	
GO:0106387	biolink:NamedThing	'de novo' GMP biosynthetic process	The chemical reactions and pathways resulting in the formation of guanosine 5'-monophosphate (GMP) through an inosine 5'-monophosphate (IMP) intermediate.	tmpzr1t_l9r_go_relaxed.owl	'de novo' guanosine 5'-monophosphate biosynthetic process							hjd	2021-07-07T17:27:01Z					biological_process											owl:Class	
GO:0098525	biolink:NamedThing	excitatory neuromuscular junction of somatic myotube	A neuromuscular junction that functions in the excitation of somatic muscle myotubes, such as an arthropod somatic muscle cells.	tmpzr1t_l9r_go_relaxed.owl								dos	2013-10-14T12:06:08Z					cellular_component											owl:Class	
GO:0018111	biolink:NamedThing	methionine racemase activity	Catalysis of the reaction: L-methionine = D-methionine.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:METHIONINE-RACEMASE-RXN|RHEA:12492|EC:5.1.1.2|KEGG_REACTION:R00655									molecular_function											owl:Class	
GO:0031732	biolink:NamedThing	CCR7 chemokine receptor binding	Binding to a CCR7 chemokine receptor.	tmpzr1t_l9r_go_relaxed.owl	MIP-3 beta receptor binding|type 1 EBV-induced G-protein coupled receptor binding|CCR7 chemokine receptor ligand													molecular_function											owl:Class	
GO:0102187	biolink:NamedThing	4alpha-carboxy,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-cholest-24-en-3beta-ol dehydrogenase/C4-decarboxylase activity	Catalysis of the reaction: 4alpha-carboxy,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-cholest-24-en-3beta-ol + NAD(1-) <=> 4alpha,14alpha-dimethyl-9beta,19-cyclo-5alpha-cholest-24-en-3-one + NADH(2-) + carbon dioxide.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-11949									molecular_function											owl:Class	
GO:0045033	biolink:NamedThing	peroxisome inheritance	The acquisition of peroxisomes by daughter cells from the mother cell after replication. In Saccharomyces cerevisiae, the number of peroxisomes cells is fairly constant; a subset of the organelles are targeted and segregated to the bud in a highly ordered, vectorial process. Efficient segregation of peroxisomes from mother to bud is dependent on the actin cytoskeleton, and active movement of peroxisomes along actin filaments is driven by the class V myosin motor protein, Myo2p.	tmpzr1t_l9r_go_relaxed.owl						Note that 'vectorial' is used in the definition in the mathematical and physical sense of pertaining to 'a quantity having direction as well as magnitude, especially as determining the position of one point in space relative to another.								biological_process											owl:Class	
GO:0015675	biolink:NamedThing	nickel cation transport	The directed movement of nickel (Ni) cations into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0047219	biolink:NamedThing	monoterpenol beta-glucosyltransferase activity	Catalysis of the reaction: (-)-menthol + UDP-D-glucose = (-)-menthyl beta-D-glucoside + H(+) + UDP.	tmpzr1t_l9r_go_relaxed.owl	UDPglucose:(-)-menthol O-beta-D-glucosyltransferase activity|uridine diphosphoglucose-monoterpenol glucosyltransferase activity|UDPglucose:monoterpenol glucosyltransferase activity|UDP-glucose:(-)-menthol O-beta-D-glucosyltransferase activity				EC:2.4.1.127|RHEA:11520|MetaCyc:2.4.1.127-RXN|KEGG_REACTION:R02179									molecular_function											owl:Class	
GO:0048250	biolink:NamedThing	iron import into the mitochondrion	The process in which iron is transported from the cytosol into the mitochondrial matrix.	tmpzr1t_l9r_go_relaxed.owl	mitochondrial iron transport|mitochondrial iron ion transmembrane transport|mitochondrial iron ion transport|mitochondrial iron cation transmembrane transport							al	2016-02-10T11:24:22Z			GO:1990925		biological_process											owl:Class	
GO:0033994	biolink:NamedThing	glucuronan lyase activity	Catalysis of the reaction: (1->4)-beta-D-glucuronan = an oligosaccharide with 4-deoxy-beta-D-gluc-4-enuronosyl end + (1->4)-beta-D-glucuronan. This reaction is the eliminative cleavage of (1->4)-beta-D-glucuronans to give oligosaccharides with 4-deoxy-beta-D-gluc-4-enuronosyl groups at their non-reducing ends. Complete degradation of glucuronans results in the formation of tetrasaccharides.	tmpzr1t_l9r_go_relaxed.owl	(1,4)-beta-D-glucuronan lyase activity				EC:4.2.2.14|MetaCyc:4.2.2.14-RXN									molecular_function											owl:Class	
GO:0045210	biolink:NamedThing	FasL biosynthetic process	The chemical reactions and pathways resulting in the formation of fas ligand (FasL or CD95L), an antigen originally found to be expressed on the cell surface of activated human T-lymphocytes and B-lymphocytes and a variety of malignant human lymphoid cell lines.	tmpzr1t_l9r_go_relaxed.owl	FasL synthesis|FASLG biosynthetic process|FasL biosynthesis|APT1LG1 biosynthetic process|FasL formation|Fas-L biosynthetic process|CD95L biosynthesis|CD178 biosynthetic process|FasL anabolism|fas ligand biosynthetic process|CD95L biosynthetic process													biological_process											owl:Class	
GO:0102510	biolink:NamedThing	pelargonidin 3-O-glucoside 5-O-glucosyltransferase (acyl-glucose dependent) activity	Catalysis of the reaction: pelargonidin 3-O-beta-D-glucoside + 1-O-vanilloyl-beta-D-glucose <=> anthocyanidin 3,5-di-O-beta-D-glucoside + vanillate + H+.	tmpzr1t_l9r_go_relaxed.owl					EC:2.4.1.299|MetaCyc:RXN-14439									molecular_function											owl:Class	
GO:0044555	biolink:NamedThing	negative regulation of heart rate in other organism	Any process that stops, prevents or reduces the frequency of heart contraction of another organism.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-03-29T03:01:20Z					biological_process											owl:Class	
GO:0071200	biolink:NamedThing	Kv4.2-DPP6 channel complex	A voltage-gated potassium channel complex that contains the peptidase-related protein DPP6 associated with the channel via interaction with the Kv alpha subunit 4.2.	tmpzr1t_l9r_go_relaxed.owl	Kv4.2-DPPX channel complex				CORUM:603			mah	2009-11-23T05:18:31Z					cellular_component											owl:Class	
GO:0043904	biolink:NamedThing	isochorismate pyruvate lyase activity	Catalysis of the reaction: isochorismate = salicylate + pyruvate.	tmpzr1t_l9r_go_relaxed.owl	IPL|isochorismate-pyruvate lyase activity				RHEA:27874|MetaCyc:RXN-1981|EC:4.2.99.21									molecular_function											owl:Class	
GO:0005340	biolink:NamedThing	nucleotide-sulfate transmembrane transporter activity	Enables the transfer of nucleotide-sulfate from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	nucleotide-sulphate transporter activity											GO:0005341		molecular_function											owl:Class	
GO:0046821	biolink:NamedThing	extrachromosomal DNA	DNA structures that are not part of a chromosome.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Extrachromosomal_DNA									cellular_component											owl:Class	
GO:0043851	biolink:NamedThing	methanol-specific methylcobalamin:coenzyme M methyltransferase activity	Catalysis of the reaction: a methylated methanol corrinoid protein + coenzyme M = a methanol corrinoid protein + methyl-CoM. This reaction is the transfer of the methyl group from the methylated corrinoid cofactor of a methylamine corrinoid protein to coenzyme M.	tmpzr1t_l9r_go_relaxed.owl	MtaA|MtaC protein:coenzyme M methyltransferase activity|methanol-specific methylcobalamin:CoM methyltransferase activity|MtaC protein: coenzyme M methyltransferase activity|MT2|methanol-specific methylcobalamin: coenzyme M methyltransferase activity|methyltransferase 2				MetaCyc:RXN-8096	This function is the second step in the pathway of methanogenesis from methanol.								molecular_function											owl:Class	
GO:0030766	biolink:NamedThing	11-O-demethyl-17-O-deacetylvindoline O-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + 11-O-demethyl-17-O-deacetylvindoline = S-adenosyl-L-homocysteine + 17-O-deacetylvindoline.	tmpzr1t_l9r_go_relaxed.owl	11-demethyl-17-deacetylvindoline 11-methyltransferase activity|tabersonine 16-O-methyltransferase activity|S-adenosyl-L-methionine:16-hydroxytabersonine 16-O-methyltransferase activity|S-adenosyl-L-methionine:11-O-demethyl-17-O-deacetylvindoline 11-O-methyltransferase activity				RHEA:20992|EC:2.1.1.94|MetaCyc:2.1.1.94-RXN									molecular_function											owl:Class	
GO:0052637	biolink:NamedThing	delta 3-trans-hexadecenoic acid phosphatidylglycerol desaturase activity	Catalysis of the reaction: 1-18:3-3-16:0-phosphatidylglycerol = 1-18:3-3-trans-16:1-phosphatidylglycerol + 2 H+. This reaction is the formation of a trans double bond between carbon 3 and carbon 4 (counting from the carboxyl end) of palmitic acid, which is specifically esterified to the sn-2 glyceryl carbon of phosphatidylglycerol.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0003048	biolink:NamedThing	regulation of systemic arterial blood pressure by norepinephrine	The regulation of blood pressure mediated by the catecholamine signaling molecule norepinephrine.	tmpzr1t_l9r_go_relaxed.owl	regulation of blood pressure by noradrenaline|blood pressure regulation by norepinephrine													biological_process											owl:Class	
GO:0005044	biolink:NamedThing	scavenger receptor activity	Combining with any modified low-density lipoprotein (LDL) or other polyanionic ligand and delivering the ligand into the cell via endocytosis. Ligands include acetylated and oxidized LDL, Gram-positive and Gram-negative bacteria, apoptotic cells, amyloid-beta fibrils, and advanced glycation end products (AGEs).	tmpzr1t_l9r_go_relaxed.owl	macrophage receptor activity					Note that many gene products that are called scavenger receptors have a broad range of potential ligands and also can be annotated to 'pattern recognition receptor activity ; GO:0038187' or its child terms, or to 'lipoprotein receptor activity ; GO:0030228' or its child terms. For receptors that transduce a signal rather than endocytose their ligand, consider instead the terms 'signaling receptor activity ; GO:0038023' and its children.								molecular_function											owl:Class	
GO:0071255	biolink:NamedThing	Cvt vesicle assembly	A vesicle organization process that takes place as part of the Cvt pathway, and results in the formation of a double membrane-bounded cytosolic structure that sequesters precursor aminopeptidase I (prAPI).	tmpzr1t_l9r_go_relaxed.owl	cytoplasm to vacuole targeting vesicle assembly|Cvt vesicle formation|Cvt vesicle biosynthesis|cytoplasm-to-vacuole targetin vesicle assembly							mah	2009-12-04T10:39:50Z					biological_process											owl:Class	
GO:0010397	biolink:NamedThing	apiogalacturonan metabolic process	The chemical reactions and pathways involving the pectic apiogalacturonan, characterized by a backbone of alpha-(1->4)-linked D-galacturonic acid residues substituted with apiose and apiobiose (D-apiofuranosyl-beta-(1->3)-D-apiose) side chains via O-2 or O-3 links.	tmpzr1t_l9r_go_relaxed.owl	apiogalacturonan metabolism													biological_process											owl:Class	
GO:0006223	biolink:NamedThing	uracil salvage	Any process that generates uracil, 2,4-dioxopyrimidine, from derivatives of it without de novo synthesis.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0043100	biolink:NamedThing	pyrimidine nucleobase salvage	Any process that generates pyrimidine nucleobases, 1,3-diazine organic nitrogenous bases, from derivatives of them without de novo synthesis.	tmpzr1t_l9r_go_relaxed.owl	pyrimidine base salvage													biological_process											owl:Class	
GO:0003937	biolink:NamedThing	IMP cyclohydrolase activity	Catalysis of the reaction: IMP + H2O = 5-formamido-1-(5-phosphoribosyl)imidazole-4-carboxamide.	tmpzr1t_l9r_go_relaxed.owl	IMP synthetase activity|inosinate cyclohydrolase activity|inosinicase activity|IMP 1,2-hydrolase (decyclizing)				Reactome:R-HSA-73797|RHEA:18445|EC:3.5.4.10|MetaCyc:IMPCYCLOHYDROLASE-RXN									molecular_function											owl:Class	
GO:0015327	biolink:NamedThing	cystine:glutamate antiporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: cystine(out) + glutamate(in) = cystine(in) + glutamate(out).	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0052778	biolink:NamedThing	diacetylchitobiose metabolic process	The chemical reactions and pathways involving diacetylchitobiose, the N,N'-diacetylated derivative of chitobiose.	tmpzr1t_l9r_go_relaxed.owl	diacetylchitobiose metabolism													biological_process											owl:Class	
GO:0052905	biolink:NamedThing	tRNA (guanine(9)-N(1))-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + guanine(9) in tRNA = N(1)-methylguanine(9) in tRNA + S-adenosyl-L-homocysteine.	tmpzr1t_l9r_go_relaxed.owl	tRNA(m(1)G(9)/m(1)A(9))Mtase activity|tRNA(m(1)G(9)/m(1)A(9))-methyltransferase activity|tRNA m(1)G(9) Mtase activity|tRNA m(1)G(9)-methyltransferase activity|tRNA (guanine-N(1)-)-methyltransferase activity				RHEA:43156|MetaCyc:RXN-12459|EC:2.1.1.221									molecular_function											owl:Class	
GO:1990386	biolink:NamedThing	mitotic cleavage furrow ingression	Advancement of the mitotic cleavage furrow from the outside of the cell inward towards the center of the cell. The cleavage furrow acts as a 'purse string' which draws tight to separate daughter cells during mitotic cytokinesis and partition the cytoplasm between the two daughter cells. The furrow ingresses until a cytoplasmic bridge is formed.	tmpzr1t_l9r_go_relaxed.owl								kmv	2014-05-29T20:58:27Z					biological_process											owl:Class	
GO:0009744	biolink:NamedThing	response to sucrose	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sucrose stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to sucrose stimulus													biological_process											owl:Class	
GO:0009319	biolink:NamedThing	cytochrome o ubiquinol oxidase complex	A protein complex that possesses cytochrome o ubiquinol oxidase activity; consists of four polypeptide subunits and associated prosthetic groups.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:CYT-O-UBIOX-CPLX	See also the molecular function term 'cytochrome o ubiquinol oxidase activity ; GO:0008827'.								cellular_component											owl:Class	
GO:1904672	biolink:NamedThing	regulation of somatic stem cell population maintenance	Any process that modulates the frequency, rate or extent of somatic stem cell population maintenance.	tmpzr1t_l9r_go_relaxed.owl								rph	2015-09-14T08:40:19Z					biological_process											owl:Class	
GO:0140633	biolink:NamedThing	CARD8 inflammasome complex assembly	The aggregation, arrangement and bonding together of a set of components to form a CARD8 inflammasome complex.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/21092						pg	2021-04-09T11:19:51Z					biological_process											owl:Class	
GO:0070225	biolink:NamedThing	sulfide dehydrogenase activity	Catalysis of the reaction: hydrogen sulfide + oxidized cytochrome c = S + reduced cytochrome c.	tmpzr1t_l9r_go_relaxed.owl	sulphide dehydrogenase activity|flavocytochrome c sulfide dehydrogenase activity				EC:1.8.2.3|RHEA:30223|MetaCyc:RXN-8156									molecular_function											owl:Class	
GO:0032408	biolink:NamedThing	MutSbeta complex binding	Binding to a MutSbeta mismatch repair complex.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0005630	biolink:NamedThing	dityrosine layer of spore wall	The outermost layer of the spore wall, as described in Saccharomyces.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0052727	biolink:NamedThing	capsanthin synthase activity	Catalysis of the reaction: antheraxanthin = capsanthin.	tmpzr1t_l9r_go_relaxed.owl	CCS|capsanthin-capsorubin synthase activity|ketoxanthophyll synthase activity				MetaCyc:RXN-7947|EC:5.3.99.8|RHEA:17373			ai	2011-08-16T03:09:21Z					molecular_function											owl:Class	
GO:0071625	biolink:NamedThing	vocalization behavior	The behavior in which an organism produces sounds by a mechanism involving its respiratory system.	tmpzr1t_l9r_go_relaxed.owl	vocalisation behaviour							mah	2010-02-10T11:02:58Z					biological_process											owl:Class	
GO:0102595	biolink:NamedThing	cyanidin 7-O-(6-O-(4-O-(glucosyl)-oxybenzoyl)-glucoside) acyltransferase (acyl-glucose dependent) activity	Catalysis of the reaction: cyanidin 3-O-glucoside-7-O-(6-O-(4-O-(glucosyl)-oxybenzoyl)-glucoside) + 1-O-4-hydroxybenzoyl-beta-D-glucose <=> cyanidin 3-O-glucoside-7-O-(6-O-(4-O-(6-O-(p-hydroxybenzoyl)-glucosyl)-oxybenzoyl)-glucoside) + beta-D-glucose.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-15374									molecular_function											owl:Class	
GO:0099153	biolink:NamedThing	synaptic transmission, serotonergic	The vesicular release of  serotonin from a presynapse, across a chemical synapse, the subsequent activation of serotonin receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse.	tmpzr1t_l9r_go_relaxed.owl	serotonergic synaptic transmission							dos	2017-07-05T14:16:51Z					biological_process											owl:Class	
GO:0005633	biolink:NamedThing	ascus lipid droplet	Any particle of coalesced lipids in an ascus or ascospore. May include associated proteins.	tmpzr1t_l9r_go_relaxed.owl	ascus lipid particle													cellular_component											owl:Class	
GO:0042469	biolink:NamedThing	versicolorin reductase activity	Catalysis of the reduction of versicolorin A to sterigmatocystin.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0000240	biolink:NamedThing	diplotene	The cell cycle phase which follows pachytene during prophase I of meiosis, during which the homologous chromosomes begin to separate and the synaptonemal complex dissolves.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Meiosis#Diplotene|Wikipedia:Diplotene	Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).								biological_process											owl:Class	
GO:0003681	biolink:NamedThing	bent DNA binding	Binding to DNA in a bent conformation.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0102385	biolink:NamedThing	patchoulol synthase activity	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate(3-) <=> seychellene + diphosphoric acid.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-13522									molecular_function											owl:Class	
GO:0061930	biolink:NamedThing	regulation of erythrocyte enucleation	Any process that modulates the frequency, rate or extent of erythrocyte enucleation.	tmpzr1t_l9r_go_relaxed.owl								dph	2017-09-05T12:48:05Z					biological_process											owl:Class	
GO:0032163	biolink:NamedThing	hyphal septin band	A septin band, i.e. a diffuse ring composed of a series of septin bars running parallel to the long axis of the cell, located at the junction between the mother cell and the germ tube (hypha) of a fungal cell growing filamentously.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0062078	biolink:NamedThing	TSC1-TSC2 complex binding	Binding to a TSC1-TSC2 complex.	tmpzr1t_l9r_go_relaxed.owl	tuberin sclerosis complex binding|tuberin-hamartin complex binding							dph	2018-10-11T12:31:42Z					molecular_function											owl:Class	
GO:0070771	biolink:NamedThing	alphaIIb-beta3 integrin-CD47-Src complex	A protein complex that consists of an alphaIIb-beta3 integrin complex bound to the cell surface antigen CD47 and the kinase c-Src.	tmpzr1t_l9r_go_relaxed.owl	ITGA2b-ITGB3-CD47-SRC complex							mah	2009-06-29T05:46:53Z					cellular_component											owl:Class	
GO:0046422	biolink:NamedThing	violaxanthin de-epoxidase activity	Catalysis of the reaction: violaxanthin + 2 ascorbate = zeaxanthin + 2 dehydroascorbate + 2 H2O; and antheraxanthin + ascorbate = zeaxanthin + dehydroascorbate + H2O.	tmpzr1t_l9r_go_relaxed.owl	violaxanthin:ascorbate oxidoreductase activity|VDE				EC:1.23.5.1|RHEA:32371									molecular_function											owl:Class	
GO:0043810	biolink:NamedThing	ornithine-acyl [acyl carrier protein] N-acyltransferase activity	Catalysis of the reaction: (3R)-3-hydroxyacyl-[acyl-carrier protein] + L-ornithine = lyso-ornithine lipid + [acyl-carrier protein]. The enzyme, found in bacteria, catalyzes the first step in the biosynthesis of ornithine lipids.	tmpzr1t_l9r_go_relaxed.owl	ornithine-acyl[acyl carrier protein] N-acyltransferase activity|L-ornithine N(alpha)-acyltransferase				RHEA:20633|EC:2.3.2.30									molecular_function											owl:Class	
GO:0032426	biolink:NamedThing	stereocilium tip	A distinct compartment at the tip of a stereocilium, distal to the site of attachment to the apical cell surface. It consists of a dense matrix bridging the barbed ends of the stereocilium actin filaments with the overlying plasma membrane, is dynamic compared to the shaft, and is required for stereocilium elongation.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0052635	biolink:NamedThing	C-20 gibberellin 2-beta-dioxygenase activity	Catalysis of the reaction: a C-20 gibberellin + 2-oxoglutarate + O2 = a C-20 2-beta-hydroxygibberellin + succinate + CO2. C-20 gibberellin refers to a gibberellin with twenty carbons.	tmpzr1t_l9r_go_relaxed.owl	C-20 gibberellin 2-oxidase activity|C-20 gibberellin 2beta-dioxygenase activity|C-20 gibberellin 2-beta-hydroxylase activity|(C-20 gibberellin-1),2-oxoglutarate:oxygen oxidoreductase (2beta-hydroxylating)|C(20) gibberellin 2-oxidase activity|C-20 gibberellin 2beta-hydroxylase activity|C-20 GA 2-oxidase activity													molecular_function											owl:Class	
GO:0005607	biolink:NamedThing	laminin-2 complex	A laminin complex composed of alpha2, beta1 and gamma1 polypeptide chains.	tmpzr1t_l9r_go_relaxed.owl	laminin-211 complex													cellular_component											owl:Class	
GO:0004982	biolink:NamedThing	N-formyl peptide receptor activity	Combining with an N-formyl peptide to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	Fmet-leu-phe receptor													molecular_function											owl:Class	
GO:1902391	biolink:NamedThing	positive regulation of N-terminal peptidyl-serine acetylation	Any process that activates or increases the frequency, rate or extent of N-terminal peptidyl-serine acetylation.	tmpzr1t_l9r_go_relaxed.owl	activation of N-terminal peptidyl-serine acetylation|up regulation of N-terminal peptidyl-serine acetylation|up-regulation of N-terminal peptidyl-serine acetylation|upregulation of N-terminal peptidyl-serine acetylation							al	2013-09-11T14:46:54Z					biological_process											owl:Class	
GO:0097432	biolink:NamedThing	hippocampal pyramidal neuron differentiation	The process in which a relatively unspecialized cell acquires specialized features of a hippocampal pyramidal neuron, a pyramidal cell of the hippocampus.	tmpzr1t_l9r_go_relaxed.owl								pr	2012-11-22T09:33:31Z					biological_process											owl:Class	
GO:0102975	biolink:NamedThing	versiconal hemiacetal acetate reductase activity	Catalysis of the reaction: versiconol acetate + NADP <=> versiconal hemiacetal acetate + NADPH.	tmpzr1t_l9r_go_relaxed.owl					RHEA:35695|EC:1.1.1.353|MetaCyc:RXN-9490									molecular_function											owl:Class	
GO:0018609	biolink:NamedThing	chlorobenzene dioxygenase activity	Catalysis of the reaction: 2,3-unsubstituted benzenoid + O2 + NAD(P)H + H+ = 2,3-cis-dihydroxydihydrobenzenoid + NAD(P)+. Substrates include 1,4-dichlorobenzene (forms 3,6-dichloro-cis-1,2-dihydroxycyclohexa-3,5-diene), 1,2,3,4-tetrachlorobenzene (forms cis-chlorobenzene dihydrodiol) and 1,2,4-trichlorobenzene (forms 3,4,6-trichloro-cis-1,2-dihydroxycyclohexa-3,5-diene).	tmpzr1t_l9r_go_relaxed.owl					EC:1.14.12.-|UM-BBD_enzymeID:e0062									molecular_function											owl:Class	
GO:0046987	biolink:NamedThing	N-acetyllactosamine beta-1,3-glucuronosyltransferase activity	Catalysis of the transfer, in a beta 1,3 linkage, of D-glucuronic acid (GlcUA) from UDP-D-glucuronic acid to N-acetyllactosamine (galactosyl beta-1,4-N-acetylglucosamine).	tmpzr1t_l9r_go_relaxed.owl	galactosyl beta-1,4 N-acetylglucosamine beta-1,3 glucuronosyltransferase activity													molecular_function											owl:Class	
GO:0035741	biolink:NamedThing	activated CD4-positive, alpha-beta T cell proliferation	The expansion of an activated CD4-positive, alpha-beta T cell population by cell division.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-03-17T02:18:39Z					biological_process											owl:Class	
GO:0018072	biolink:NamedThing	peptidyl-L-glutamyl 5-glycerylphosphorylethanolamine biosynthetic process from peptidyl-glutamic acid	The modification of peptidyl-glutamic acid residues by the covalent attachment of ethanolamine, itself further modified by the addition of a phosphoglycerol unit.	tmpzr1t_l9r_go_relaxed.owl	peptidyl-L-glutamyl 5-glycerylphosphorylethanolamine formation from peptidyl-glutamic acid|peptidyl-L-glutamyl 5-glycerylphosphorylethanolamine synthesis from peptidyl-glutamic acid|peptidyl-L-glutamyl 5-glycerylphosphorylethanolamine anabolism from peptidyl-glutamic acid				RESID:AA0170									biological_process											owl:Class	
GO:0015539	biolink:NamedThing	hexuronate:cation symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: hexuronate(out) + cation(out) = hexuronate(in) + cation(in). The hexuronate may be glucuronate or galacturonate.	tmpzr1t_l9r_go_relaxed.owl	hexuronate (glucuronate/galacturonate) porter activity|hexuronate porter activity													molecular_function											owl:Class	
GO:1905091	biolink:NamedThing	positive regulation of parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization	Any process that activates or increases the frequency, rate or extent of parkin-mediated mitophagy in response to mitochondrial depolarization.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of parkin-mediated mitophagy in response to mitochondrial depolarization|up regulation of parkin-mediated mitophagy in response to mitochondrial depolarization|positive regulation of Park2-mediated stimulation of mitophagy in response to mitochondrial depolarization|upregulation of parkin-mediated mitophagy in response to mitochondrial depolarization|positive regulation of PRKN-mediated stimulation of mitophagy in response to mitochondrial depolarization|activation of parkin-mediated mitophagy in response to mitochondrial depolarization							pad	2016-03-30T15:34:47Z					biological_process											owl:Class	
GO:0036024	biolink:NamedThing	protein C inhibitor-TMPRSS7 complex	A heterodimeric protein complex that contains protein C inhibitor (SERPINA5) and transmembrane protease serine 7 (TMPRSS7); formation of the complex inhibits the serine protease activity of transmembrane protease serine 7.	tmpzr1t_l9r_go_relaxed.owl	serpin A5-TMPRSS7 complex|SERPINA5-TMPRSS7 complex|plasma serine protease inhibitor-TMPRSS7 complex|protein C inhibitor-matriptase-3 complex|PCI-TMPRSS7 complex|protein C inhibitor-transmembrane protease serine 7 complex							bf	2011-10-19T01:25:06Z					cellular_component											owl:Class	
GO:0036375	biolink:NamedThing	Kibra-Ex-Mer complex	An apical protein complex that contains the proteins Kibra, Expanded and Merlin (Mer), or orthologs thereof. In humans, the complex contains KIBRA, FDM6 and NF2.	tmpzr1t_l9r_go_relaxed.owl	Kbr, Ex and Mer complex|KEM complex							bf	2013-05-07T10:05:15Z					cellular_component											owl:Class	
GO:1903983	biolink:NamedThing	positive regulation of microvillus length	A process that increases the length of a microvillus.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of regulation of microvillus length|upregulation of regulation of microvillus length|activation of regulation of microvillus length|up regulation of regulation of microvillus length							als	2015-03-03T13:23:58Z					biological_process											owl:Class	
GO:0047233	biolink:NamedThing	N-acetylneuraminylgalactosylglucosylceramide beta-1,4-N-acetylgalactosaminyltransferase activity	Catalysis of the reaction: N-acetylneuraminyl-2,3-alpha-D-galactosyl-1,4-beta-D-glucosylceramide + UDP-N-acetylgalactosamine = N-acetyl-beta-D-galactosaminyl-1,4-(N-acetyl-alpha-neuraminyl-2,3)-beta-D-galactosyl-1,4-beta-D-glucosylceramide + UDP.	tmpzr1t_l9r_go_relaxed.owl	uridine diphosphoacetylgalactosamine-acetylneuraminyl(alpha2->3)galactosyl(beta1->4)glucosyl beta1->4-acetylgalactosaminyltransferase activity|UDP-N-acetyl-D-galactosamine:N-acetylneuraminyl-2,3-alpha-D-galactosyl-1,4-beta-D-glucosylceramide beta-1,4-N-acetylgalactosaminyltransferase activity				EC:2.4.1.165|RHEA:13569|MetaCyc:2.4.1.165-RXN									molecular_function											owl:Class	
GO:0015395	biolink:NamedThing	nucleoside transmembrane transporter activity, down a concentration gradient	Enables the transfer of a nucleoside, from one side of a membrane to the other, down the concentration gradient.	tmpzr1t_l9r_go_relaxed.owl	equilibrative nucleoside transporter activity|equilibrative nucleoside transmembrane transporter, nitrobenzyl-thioinosine-insensitive activity|equilibrative nucleoside transmembrane transporter, nitrobenzyl-thioinosine-sensitive activity											GO:0015397|GO:0015396		molecular_function											owl:Class	
GO:0019465	biolink:NamedThing	aspartate transamidation	The exchange of the amino group of aspartate, the anion derived from aspartic acid, for another amino group.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:ASPARTATESYN-PWY|MetaCyc:ASPARTATE-DEG1-PWY									biological_process											owl:Class	
GO:0004769	biolink:NamedThing	steroid delta-isomerase activity	Catalysis of the reaction: a 3-oxo-delta(5)-steroid = a 3-oxo-delta(4)-steroid.	tmpzr1t_l9r_go_relaxed.owl	delta5-ketosteroid isomerase activity|hydroxysteroid isomerase activity|delta5-3-ketosteroid isomerase activity|delta(5)-3-keto steroid isomerase activity|3-oxosteroid isomerase activity|steroid D-isomerase activity|delta(5)-3-ketosteroid isomerase activity|delta5-steroid isomerase activity|delta(5)-3-oxosteroid isomerase activity|delta5-3-keto steroid isomerase activity|delta5-3-oxosteroid isomerase activity|3-oxosteroid delta5-delta4-isomerase activity|delta5(or delta4)-3-keto steroid isomerase activity|delta(5)-steroid isomerase activity|steroid isomerase activity				Reactome:R-HSA-195690|Reactome:R-HSA-193073|Reactome:R-HSA-193052|Reactome:R-HSA-193961|MetaCyc:STEROID-DELTA-ISOMERASE-RXN|RHEA:14709|Reactome:R-HSA-6807052|EC:5.3.3.1									molecular_function											owl:Class	
GO:0047466	biolink:NamedThing	2-chloro-4-carboxymethylenebut-2-en-1,4-olide isomerase activity	Catalysis of the reaction: cis-2-chloro-4-carboxymethylenebut-2-en-1,4-olide = trans-2-chloro-4-carboxymethylenebut-2-en-1,4-olide.	tmpzr1t_l9r_go_relaxed.owl	2-chloro-4-carboxymethylenebut-2-en-1,4-olide cis-trans-isomerase activity|2-chlorocarboxymethylenebutenolide isomerase activity|chlorodienelactone isomerase activity				KEGG_REACTION:R04576|EC:5.2.1.10|MetaCyc:5.2.1.10-RXN|UM-BBD_reactionID:r0278|RHEA:10924							GO:0018840		molecular_function											owl:Class	
GO:0008199	biolink:NamedThing	ferric iron binding	Binding to a ferric iron ion, Fe(III).	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0009349	biolink:NamedThing	riboflavin synthase complex	An flavoprotein that catalyzes the reaction the breakdown of dimethyl(ribityl)lumazine to form riboflavin and ribitylamino-amino-dihydroxypyrimidine.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0043585	biolink:NamedThing	nose morphogenesis	The process in which the anatomical structures of the nose are generated and organized. The nose is the specialized structure of the face that serves as the organ of the sense of smell and as part of the respiratory system. Includes the nasi externus (external nose) and cavitas nasi (nasal cavity).	tmpzr1t_l9r_go_relaxed.owl	nasus morphogenesis													biological_process											owl:Class	
GO:0019343	biolink:NamedThing	cysteine biosynthetic process via cystathionine	The chemical reactions and pathways resulting in the formation of cysteine, via the intermediate cystathionine.	tmpzr1t_l9r_go_relaxed.owl	cysteine synthesis via cystathionine|cysteine anabolism via cystathionine|cysteine formation via cystathionine													biological_process											owl:Class	
GO:0044844	biolink:NamedThing	meiotic interphase II	The cell cycle phase which begins at the end of meiosis I cytokinesis and ends when meiosis II prophase begins. During meiotic interphase II no DNA replication takes place, but the centrioles duplicate and spindle fibres emerge.	tmpzr1t_l9r_go_relaxed.owl						Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).		jl	2014-03-26T16:52:27Z					biological_process											owl:Class	
GO:0009784	biolink:NamedThing	transmembrane receptor histidine kinase activity	Combining with a signal and transmitting the signal from one side of a membrane to the other to initiate a change in cell activity by catalysis of the reaction: ATP + a protein-L-histidine = ADP + a protein-L-histidine phosphate.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0061431	biolink:NamedThing	cellular response to methionine	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methionine stimulus.	tmpzr1t_l9r_go_relaxed.owl								dph	2012-02-07T10:27:01Z					biological_process											owl:Class	
GO:0003265	biolink:NamedThing	regulation of primary heart field cardioblast proliferation	Any process that modulates the frequency, rate or extent of cardioblast proliferation in the primary heart field. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating. In mammals the primary heart field gives rise to the left ventricle.	tmpzr1t_l9r_go_relaxed.owl	regulation of first heart field cardioblast proliferation|regulation of FHF cardioblast proliferation|regulation of first heart field cardiac proliferation							dph	2009-10-15T02:25:26Z					biological_process											owl:Class	
GO:0030841	biolink:NamedThing	positive regulation of intermediate filament polymerization	Any process that activates or increases the frequency, rate or extent of intermediate filament polymerization.	tmpzr1t_l9r_go_relaxed.owl	stimulation of intermediate filament polymerization|activation of intermediate filament polymerization|positive regulation of intermediate filament polymerization and/or depolymerization|upregulation of intermediate filament polymerization|up-regulation of intermediate filament polymerization|up regulation of intermediate filament polymerization					Note that this term was split from 'positive regulation of intermediate filament polymerization and/or depolymerization ; GO:0045826' (sibling term 'positive regulation of intermediate filament depolymerization ; GO:0030844').								biological_process											owl:Class	
GO:1990538	biolink:NamedThing	xylan O-acetyltransferase activity	Catalysis of the reaction: acetyl-CoA + a xylan= CoA + an acetylated xylan.	tmpzr1t_l9r_go_relaxed.owl								tb	2014-11-18T20:02:51Z					molecular_function											owl:Class	
GO:0022625	biolink:NamedThing	cytosolic large ribosomal subunit	The large subunit of a ribosome located in the cytosol.	tmpzr1t_l9r_go_relaxed.owl	prokaryotic large ribosomal subunit|eukaryotic ribosomal LSU|50S ribosomal subunit|60S ribosomal subunit											GO:0009282|GO:0005842|GO:0030498|GO:0030872		cellular_component											owl:Class	
GO:1901924	biolink:NamedThing	positive regulation of sclerotium development	Any process that activates or increases the frequency, rate or extent of sclerotium development.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of sclerotium development|upregulation of sclerotium development|up regulation of sclerotium development|activation of sclerotium development							di	2013-02-15T20:00:28Z					biological_process											owl:Class	
GO:1903165	biolink:NamedThing	response to polycyclic arene	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a polycyclic arene stimulus.	tmpzr1t_l9r_go_relaxed.owl								mr	2014-07-09T18:32:59Z					biological_process											owl:Class	
GO:0015414	biolink:NamedThing	ABC-type nitrate transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + nitrate(out) = ADP + phosphate + nitrate(in).	tmpzr1t_l9r_go_relaxed.owl	nitrate transporting ATPase activity|nitrate transmembrane-transporting ATPase activity|nitrate-transporting ATPase activity|ATPase-coupled nitrate transmembrane transporter activity|nitrate ABC transporter				EC:7.3.2.4|MetaCyc:3.6.3.26-RXN|RHEA:13181									molecular_function											owl:Class	
GO:0061826	biolink:NamedThing	podosome ring	The ring structure surrounding the podosome core, containing proteins such as vinculin and talin.	tmpzr1t_l9r_go_relaxed.owl								dph	2017-01-14T14:44:53Z					cellular_component											owl:Class	
GO:0005919	biolink:NamedThing	pleated septate junction	A septate junction in which regular arrays of electron-dense septae span the intermembrane space.	tmpzr1t_l9r_go_relaxed.owl	pleated desmosome													cellular_component											owl:Class	
GO:0070858	biolink:NamedThing	negative regulation of bile acid biosynthetic process	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of bile acids.	tmpzr1t_l9r_go_relaxed.owl	downregulation of bile acid biosynthetic process|down-regulation of bile acid biosynthetic process|down regulation of bile acid biosynthetic process|negative regulation of bile acid biosynthesis|negative regulation of bile acid synthesis|negative regulation of bile acid formation|inhibition of bile acid biosynthetic process|negative regulation of bile acid anabolism							mah	2009-08-14T03:16:40Z					biological_process											owl:Class	
GO:0018816	biolink:NamedThing	2-hydroxyisobutyrate dehydratase activity	Catalysis of the reaction: 2-hydroxyisobutyrate = H2O + methacrylate.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0618									molecular_function											owl:Class	
GO:0051028	biolink:NamedThing	mRNA transport	The directed movement of mRNA, messenger ribonucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0071194	biolink:NamedThing	Kv4.2-KChIP3 channel complex	A voltage-gated potassium channel complex that contains the Kv channel interacting protein KChIP3 associated with the channel via interaction with the Kv alpha subunit 4.2.	tmpzr1t_l9r_go_relaxed.owl					CORUM:608			mah	2009-11-23T04:58:41Z					cellular_component											owl:Class	
GO:0036136	biolink:NamedThing	kynurenine-oxaloacetate transaminase activity	Catalysis of the reaction: L-kynurenine + 2-oxoglutarate = 4-(2-aminophenyl)-2,4-dioxobutanoate + L-aspartate.	tmpzr1t_l9r_go_relaxed.owl	L-kynurenine-oxaloacetate transaminase activity							bf	2012-03-06T02:14:11Z					molecular_function											owl:Class	
GO:0008682	biolink:NamedThing	2-octoprenyl-3-methyl-6-methoxy-1,4-benzoquinone hydroxylase activity	Catalysis of the reaction: 2-octoprenyl-3-methyl-6-methoxy-1,4-benzoquinone + O2 = 2-octoprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinone.	tmpzr1t_l9r_go_relaxed.owl	demethoxyubiquinone monooxygenase|demethoxy-ubiquinone hydroxylase				RHEA:50908|MetaCyc:OCTAPRENYL-METHYL-METHOXY-BENZOQ-OH-RXN|EC:1.14.99.60									molecular_function											owl:Class	
GO:0014023	biolink:NamedThing	neural rod formation	The formation of a solid rod of neurectoderm derived from the neural keel. The neural rod is roughly circular in cross section. Neural rod formation occurs during primary neurulation in teleosts.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0015714	biolink:NamedThing	phosphoenolpyruvate transport	The directed movement of phosphoenolpyruvate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0047410	biolink:NamedThing	N-formylmethionylaminoacyl-tRNA deformylase activity	Catalysis of the reaction: H2O + charged-fMet-tRNAs = L-methionylaminoacyl-tRNA + formate.	tmpzr1t_l9r_go_relaxed.owl	N-formyl-L-methionylaminoacyl-tRNA amidohydrolase activity				MetaCyc:3.5.1.27-RXN									molecular_function											owl:Class	
GO:0019874	biolink:NamedThing	6-aminohexanoate-cyclic-dimer hydrolase activity	Catalysis of the reaction: 1,8-diazacyclotetradecane-2,9-dione + H(2)O = N-(6-aminohexanoyl)-6-aminohexanoate.	tmpzr1t_l9r_go_relaxed.owl	1,8-diazacyclotetradecane-2,9-dione lactamhydrolase activity				MetaCyc:3.5.2.12-RXN|RHEA:16225|EC:3.5.2.12|KEGG_REACTION:R03448|UM-BBD_reactionID:r1097									molecular_function											owl:Class	
GO:0072492	biolink:NamedThing	host cell mitochondrial intermembrane space	The region between the inner and outer lipid bilayers of the host cell mitochondrial envelope.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-12-15T11:44:02Z					cellular_component											owl:Class	
GO:0031035	biolink:NamedThing	myosin filament disassembly	The disassembly of a filament composed of myosin molecules.	tmpzr1t_l9r_go_relaxed.owl	myosin depolymerization													biological_process											owl:Class	
GO:0003121	biolink:NamedThing	epinephrine-mediated vasodilation	A vasodilation process resulting from secretion of epinephrine into the bloodstream or released by nerve endings.	tmpzr1t_l9r_go_relaxed.owl	regulation of vasodilation by epinephrine|regulation of vasodilation by neuronal epinephrine|regulation of vasodilation by circulating adrenaline|regulation of vasodilation by neuronal adrenaline|regulation of vasodilation by adrenaline|regulation of vasodilation by circulating epinephrine											GO:0003124|GO:0003123		biological_process											owl:Class	
GO:1904976	biolink:NamedThing	cellular response to bleomycin	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bleomycin stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2016-02-18T15:21:31Z					biological_process											owl:Class	
GO:0102572	biolink:NamedThing	N-glutamylanilide hydrolase activity	Catalysis of the reaction: N5-phenyl-L-glutamine + H2O = L-glutamate + aniline + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-15251|RHEA:50684									molecular_function											owl:Class	
GO:1901986	biolink:NamedThing	response to ketamine	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ketamine stimulus.	tmpzr1t_l9r_go_relaxed.owl								dph	2013-03-15T19:16:35Z					biological_process											owl:Class	
GO:0043631	biolink:NamedThing	RNA polyadenylation	The enzymatic addition of a sequence of adenylyl residues at the 3' end of an RNA molecule.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0120159	biolink:NamedThing	rRNA pseudouridine synthase activity	Catalysis of the reaction: an rRNA uridine = an rRNA pseudouridine. Conversion of uridine in an rRNA molecule to pseudouridine by rotation of the C1'-N-1 glycosidic bond of uridine in RNA to a C1'-C5.	tmpzr1t_l9r_go_relaxed.owl	23S rRNA pseudouridine(2604) synthase|21S rRNA pseudouridine(2819) synthase|16S rRNA pseudouridine(516) synthase|23S rRNA pseudouridine(1911/1915/1917) synthase|23S rRNA pseudouridine(2457) synthase|23S rRNA pseudouridine(955/2504/2580) synthase|23S rRNA pseudouridine(2605) synthase|23S rRNA pseudouridine(746) synthase				EC:5.4.99.24|EC:5.4.99.22|EC:5.4.99.29|EC:5.4.99.19|EC:5.4.99.43|EC:5.4.99.21|EC:5.4.99.20|EC:5.4.99.23			krc	2018-05-11T21:24:19Z					molecular_function											owl:Class	
GO:0045281	biolink:NamedThing	succinate dehydrogenase complex	A multimeric complex which consists of flavoprotein (subunit A ; InterPro:IPR003952), iron-sulfur protein (subunit B) and membrane-bound cytochrome b560 (subunit C; InterPro:IPR000701). In some Archaea, the membrane-bound subunits (C or C and D) do not necessarily contain heme. Membrane-bound subunits can bind or react with quinones.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0050031	biolink:NamedThing	L-pipecolate oxidase activity	Catalysis of the reaction: L-pipecolate + O(2) = 2,3,4,5-tetrahydropyridine-2-carboxylate + H(2)O(2) + H(+). Delta1-piperideine-6-carboxylate is also known as 2,3,4,5-tetrahydropyridine-2-carboxylate.	tmpzr1t_l9r_go_relaxed.owl	L-pipecolic acid oxidase activity|L-pipecolate:oxygen 1,6-oxidoreductase activity				MetaCyc:L-PIPECOLATE-OXIDASE-RXN|Reactome:R-HSA-6783880|RHEA:11992|KEGG_REACTION:R02204|EC:1.5.3.7									molecular_function											owl:Class	
GO:0052893	biolink:NamedThing	N1-acetylspermine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity	Catalysis of the reaction: N1-acetylspermine + oxygen + H2O = N-(3-acetamidopropyl)-4-aminobutanal + propane-1,3-diamine + hydrogen peroxide.	tmpzr1t_l9r_go_relaxed.owl	polyamine oxidase (propane-1,3-diamine-forming) activity				EC:1.5.3.14|MetaCyc:RXN-10465|RHEA:25996									molecular_function											owl:Class	
GO:0051221	biolink:NamedThing	tungsten incorporation into metallo-sulfur cluster	The incorporation of tungsten into a metallo-sulfur cluster.	tmpzr1t_l9r_go_relaxed.owl	tungsten incorporation into metallo-sulphur cluster													biological_process											owl:Class	
GO:0070021	biolink:NamedThing	transforming growth factor beta ligand-receptor complex	A protein complex that is formed by the association of a TGF-beta dimeric ligand with 2 molecules of each receptor molecule, TGF-beta type I receptor and TGF-beta type II receptor. The receptor molecules may form homo- or heterodimers but only once bound by the ligand.	tmpzr1t_l9r_go_relaxed.owl	TGFbeta ligand-receptor complex|TGF-beta1-beta2 ligand-receptor complex|TGFbeta1 ligand-receptor complex|transforming growth factor beta1-type II receptor-type I receptor complex|TGFb ligand-receptor complex|TGF-beta 1:type II receptor:type I receptor complex|TGF-beta2 ligand-receptor complex|TGFbeta1-beta2 ligand-receptor complex|TGF-beta ligand-receptor complex|TGF-beta1-type II receptor-type I receptor complex|TGF-beta receptor II-TGF-beta receptor I-TGF-beta1 complex|TGF-beta1 ligand-receptor complex|TGFbeta2 ligand-receptor complex													cellular_component											owl:Class	
GO:0070324	biolink:NamedThing	thyroid hormone binding	Binding to thyroxine (T4) or triiodothyronine (T3), tyrosine-based hormones produced by the thyroid gland.	tmpzr1t_l9r_go_relaxed.owl	triiodothyronine binding|thyroxine binding													molecular_function											owl:Class	
GO:0010077	biolink:NamedThing	maintenance of inflorescence meristem identity	The process in which an organism retains a population of inflorescence meristem cells, preventing the commitment of all stem cell progeny to a differentiated cell fate.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0021762	biolink:NamedThing	substantia nigra development	The progression of the substantia nigra over time from its initial formation until its mature state. The substantia nigra is the layer of gray substance that separates the posterior parts of the cerebral peduncles (tegmentum mesencephali) from the anterior parts; it normally includes a posterior compact part with many pigmented cells (pars compacta) and an anterior reticular part whose cells contain little pigment (pars reticularis).	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0006063	biolink:NamedThing	uronic acid metabolic process	The chemical reactions and pathways involving uronic acid, any monocarboxylic acid formally derived by oxidizing to a carboxyl group the terminal hydroxymethylene group of either an aldose with four or more carbon atoms in the molecule, or of any glycoside derived from such an aldose.	tmpzr1t_l9r_go_relaxed.owl	uronic acid metabolism													biological_process											owl:Class	
GO:0033711	biolink:NamedThing	4-phosphoerythronate dehydrogenase activity	Catalysis of the reaction: 4-phospho-D-erythronate + NAD(+) = (R)-3-hydroxy-2-oxo-4-phosphonooxybutanoate + H(+) + NADH.	tmpzr1t_l9r_go_relaxed.owl	erythronate-4-phosphate dehydrogenase activity|PdxB|4PE dehydrogenase activity|PdxB 4PE dehydrogenase activity|4-phospho-D-erythronate:NAD+ 2-oxidoreductase activity|4-O-phosphoerythronate dehydrogenase activity				KEGG_REACTION:R04210|MetaCyc:ERYTHRON4PDEHYDROG-RXN|RHEA:18829|EC:1.1.1.290									molecular_function											owl:Class	
GO:0140497	biolink:NamedThing	mannan polymerase II complex	A complex with alpha-(1->6)-mannosyltransferase activity, located in the cis Golgi membrane; adds mannan to N-linked glycans on proteins as part of the elongation of alpha 1,6-linked Man backbone. In S. cerevisiae, contains Mnn9p, Anp1p, Mnn10p, Mnn11p, and Hoc1p.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/19817						pg	2020-07-22T14:33:57Z					cellular_component											owl:Class	
GO:0001608	biolink:NamedThing	G protein-coupled nucleotide receptor activity	Combining with a nucleotide and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.	tmpzr1t_l9r_go_relaxed.owl	G protein coupled nucleotide receptor activity|nucleotide receptor activity, G protein coupled|G-protein coupled nucleotide receptor activity|nucleotide receptor activity, G-protein coupled													molecular_function											owl:Class	
GO:0052629	biolink:NamedThing	phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity	Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate + H2O = a 1-phosphatidyl-1D-myo-inositol 5-phosphate + phosphate + 2 H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-10958|Reactome:R-HSA-6809944|Reactome:R-HSA-6809778|Reactome:R-HSA-1676065|Reactome:R-HSA-6809320|Reactome:R-HSA-1676105|RHEA:39019|EC:3.1.3.95|Reactome:R-HSA-1676203									molecular_function											owl:Class	
GO:0019115	biolink:NamedThing	benzaldehyde dehydrogenase [NAD(P)+] activity	Catalysis of the reaction: benzaldehyde + NAD(P)+ + H2O = benzoate + NAD(P)H + H+.	tmpzr1t_l9r_go_relaxed.owl					EC:1.2.1.-									molecular_function											owl:Class	
GO:0005731	biolink:NamedThing	nucleolus organizer region	A region of a chromosome where nucleoli form during interphase, and where genes encoding the largest rRNA precursor transcript are tandemly arrayed.	tmpzr1t_l9r_go_relaxed.owl	NOR|nucleolus organiser region|nucleolus organizer complex				Wikipedia:Nucleolus_organizer_region									cellular_component											owl:Class	
GO:0102073	biolink:NamedThing	OPC8-trans-2-enoyl-CoA hydratase activity	Catalysis of the reaction: OPC8-3-hydroxyacyl-CoA <=> OPC8-trans-2-enoyl-CoA + H2O.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-10697									molecular_function											owl:Class	
GO:0022818	biolink:NamedThing	sodium ion uniporter activity	Catalysis of the active transport of a sodium ion across a membrane by a mechanism involving conformational change, where energy for active transport is derived from membrane potential if the solute is charged.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0010263	biolink:NamedThing	tricyclic triterpenoid biosynthetic process	The chemical reactions and pathways resulting in the formation of tricyclic triterpenoid compounds, terpenoids with 6 isoprene units and 3 carbon rings.	tmpzr1t_l9r_go_relaxed.owl	tricyclic triterpenoid synthesis|tricyclic triterpenoid anabolism|tricyclic triterpenoid formation|tricyclic triterpenoid biosynthesis													biological_process											owl:Class	
GO:0097513	biolink:NamedThing	myosin II filament	A bipolar filament composed of myosin II molecules.	tmpzr1t_l9r_go_relaxed.owl								pr	2013-10-16T13:06:20Z					cellular_component											owl:Class	
GO:0080027	biolink:NamedThing	response to herbivore	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a herbivore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1904308	biolink:NamedThing	cellular response to desipramine	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a desipramine stimulus.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-06-10T17:00:37Z					biological_process											owl:Class	
GO:0021958	biolink:NamedThing	gracilis tract morphogenesis	Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the dorsal root ganglion towards target cells in the medulla. This axonal process is a member of those that make up the gracilis tract, a group of axons that are from neurons involved in proprioception from the lower trunk and lower limb.	tmpzr1t_l9r_go_relaxed.owl	tract of Goll morphogenesis													biological_process											owl:Class	
GO:0043049	biolink:NamedThing	otic placode formation	The initial developmental process that will lead to the formation of the vertebrate inner ear. The otic placode forms as a thickening of the head ectoderm adjacent to the developing hindbrain.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0030946	biolink:NamedThing	protein tyrosine phosphatase activity, metal-dependent	Catalysis of the reaction: protein tyrosine phosphate + H2O = protein tyrosine + phosphate. This reaction requires metal ions.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0060344	biolink:NamedThing	liver trabecula formation	The process of creating a trabecula in the liver. A trabecula is a tissue element in the form of a small beam, strut or rod.	tmpzr1t_l9r_go_relaxed.owl	liver trabeculation|liver trabecula biogenesis													biological_process											owl:Class	
GO:0033810	biolink:NamedThing	anthocyanin 5-O-glucoside 6'''-O-malonyltransferase activity	Catalysis of the reaction: malonyl-CoA + pelargonidin 3-O-(6-caffeoyl-beta-D-glucoside) 5-O-beta-D-glucoside = CoA + 4'''-demalonylsalvianin.	tmpzr1t_l9r_go_relaxed.owl	malonyl-CoA:pelargonidin-3-O-(6-caffeoyl-beta-D-glucoside)-5-O-beta-D-glucoside 6'''-O-malonyltransferase activity|Ss5MaT1				RHEA:21988|EC:2.3.1.172|MetaCyc:2.3.1.172-RXN									molecular_function											owl:Class	
GO:0018535	biolink:NamedThing	nicotine dehydrogenase activity	Catalysis of the reaction: nicotine + acceptor + H2O = (S)-6-hydroxynicotine + reduced acceptor.	tmpzr1t_l9r_go_relaxed.owl	nicotine:acceptor 6-oxidoreductase (hydroxylating)|D-nicotine oxidase activity|nicotine oxidase activity|nicotine:(acceptor) 6-oxidoreductase (hydroxylating)				MetaCyc:NICOTINE-DEHYDROGENASE-RXN|UM-BBD_enzymeID:e0337|EC:1.5.99.4|RHEA:14769									molecular_function											owl:Class	
GO:0030619	biolink:NamedThing	U1 snRNA binding	Binding to a U1 small nuclear RNA (U1 snRNA).	tmpzr1t_l9r_go_relaxed.owl						Note that this term may be useful for annotating other small nuclear RNAs (snRNAs).								molecular_function											owl:Class	
GO:0050209	biolink:NamedThing	polyvinyl-alcohol oxidase activity	Catalysis of the reaction: polyvinyl alcohol + O2 = oxidized polyvinyl alcohol + H2O2.	tmpzr1t_l9r_go_relaxed.owl	polyvinyl-alcohol:oxygen oxidoreductase activity|dehydrogenase, polyvinyl alcohol|PVA oxidase activity				EC:1.1.3.30|MetaCyc:POLYVINYL-ALCOHOL-OXIDASE-RXN|RHEA:21688									molecular_function											owl:Class	
GO:0120160	biolink:NamedThing	intraciliary transport particle A binding	Binding to an intraciliary transport particle A (IFT A) complex.	tmpzr1t_l9r_go_relaxed.owl	intraflagellar transport particle A binding|intraflagellar transport complex A binding|IFT A complex binding|intraciliary transport complex A binding							krc	2018-05-11T22:28:11Z					molecular_function											owl:Class	
GO:0061635	biolink:NamedThing	regulation of protein complex stability	Any process that affects the structure and integrity of a protein complex by altering the likelihood of its assembly or disassembly.	tmpzr1t_l9r_go_relaxed.owl								dph	2014-08-13T14:40:21Z					biological_process											owl:Class	
GO:0004049	biolink:NamedThing	anthranilate synthase activity	Catalysis of the reaction: chorismate + L-glutamine = anthranilate + pyruvate + L-glutamate.	tmpzr1t_l9r_go_relaxed.owl	anthranilate synthetase activity|chorismate pyruvate-lyase (amino-accepting) activity				EC:4.1.3.27|RHEA:21732|MetaCyc:ANTHRANSYN-RXN									molecular_function											owl:Class	
GO:0080018	biolink:NamedThing	anthocyanin 5-O-glucosyltransferase activity	Catalysis of the reaction: an anthocyanin + UDP-D-glucose = an anthocyanin-5-O-glucoside + UDP.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0015264	biolink:NamedThing	methylammonium channel activity	Enables the facilitated diffusion of methylammonium (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism. Methylammonium is CH3NH2.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0090449	biolink:NamedThing	phloem glucosinolate loading	The process of loading glucosinolates into the sieve tube or companion cell of the phloem for long distance transport from source to sink.	tmpzr1t_l9r_go_relaxed.owl								tb	2012-09-07T16:21:22Z					biological_process											owl:Class	
GO:0070400	biolink:NamedThing	teichoic acid D-alanylation	The formation of a D-alanyl ester of teichoic acid. Alanylation of teichoic acids modulates the properties of the bacterial cell wall and modulates the inflammatory properties of the teichoic acid.	tmpzr1t_l9r_go_relaxed.owl	teichoic acid alanylation													biological_process											owl:Class	
GO:0034732	biolink:NamedThing	transcription factor TFIIIB-alpha complex	A transcription factor TFIIIB-beta complex that contains the TATA-binding protein (TBP), B'' and a specialized homolog of the conserved subunit BRF referred to as BRFU or TFIIIB50, which found in human but not conserved in yeast; the complex is involved in the regulation of transcription from type 3 (upstream) RNA polymerase III promoters.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0043125	biolink:NamedThing	ErbB-3 class receptor binding	Binding to the protein-tyrosine kinase receptor ErbB-3/HER3.	tmpzr1t_l9r_go_relaxed.owl	Neu/ErbB-2 receptor activity|HER3 receptor binding													molecular_function											owl:Class	
GO:0034674	biolink:NamedThing	integrin alpha5-beta1 complex	An integrin complex that comprises one alpha5 subunit and one beta1 subunit.	tmpzr1t_l9r_go_relaxed.owl	alpha5-beta1 integrin complex|ITGA5-ITGB1 complex|VLA-5 complex													cellular_component											owl:Class	
GO:0050188	biolink:NamedThing	phosphoenolpyruvate mutase activity	Catalysis of the reaction: phosphoenolpyruvate = 3-phosphonopyruvate.	tmpzr1t_l9r_go_relaxed.owl	PEPPM|PEP phosphomutase activity|phosphoenolpyruvate-phosphonopyruvate phosphomutase activity|phosphoenolpyruvate 2,3-phosphonomutase activity|PEP mutase activity|phosphoenolpyruvate phosphomutase activity				KEGG_REACTION:R00661|RHEA:17013|MetaCyc:PHOSPHOENOLPYRUVATE-MUTASE-RXN|EC:5.4.2.9									molecular_function											owl:Class	
GO:0008785	biolink:NamedThing	alkyl hydroperoxide reductase activity	Catalysis of the reaction: octane hydroperoxide + NADH + H+ = H2O + NAD+ + 1-octanol.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0684|Reactome:R-HSA-1222526									molecular_function											owl:Class	
GO:0060928	biolink:NamedThing	atrioventricular node cell development	The process whose specific outcome is the progression of an atrioventricular (AV) node cell over time, from its formation to the mature state.	tmpzr1t_l9r_go_relaxed.owl	AV node cell development							dph	2009-09-29T11:59:26Z					biological_process											owl:Class	
GO:0061685	biolink:NamedThing	diphthine methylesterase activity	Catalysis of the reaction: diphthine methyl ester + H2O <=> diphthine + H+ + methanol.	tmpzr1t_l9r_go_relaxed.owl					RHEA:42656|EC:3.1.1.97			dph	2015-03-04T16:00:21Z					molecular_function											owl:Class	
GO:0047548	biolink:NamedThing	2-methyleneglutarate mutase activity	Catalysis of the reaction: 2-methyleneglutarate = 2-methylene-3-methylsuccinate.	tmpzr1t_l9r_go_relaxed.owl	2-methyleneglutarate carboxy-methylenemethylmutase activity|alpha-methyleneglutarate mutase activity				MetaCyc:2-METHYLENEGLUTARATE-MUTASE-RXN|KEGG_REACTION:R03908|EC:5.4.99.4|RHEA:13793									molecular_function											owl:Class	
GO:0004484	biolink:NamedThing	mRNA guanylyltransferase activity	Catalysis of the reaction: GTP + (5')pp-Pur-mRNA = diphosphate + G(5')ppp-Pur-mRNA; G(5')ppp-Pur-mRNA is mRNA containing a guanosine residue linked 5' through three phosphates to the 5' position of the terminal residue.	tmpzr1t_l9r_go_relaxed.owl	GTP--RNA guanylyltransferase activity|mRNA capping enzyme activity|GTP:mRNA guanylyltransferase activity|messenger RNA guanylyltransferase activity|protein lambda2				MetaCyc:MRNA-GUANYLYLTRANSFERASE-RXN|RHEA:54592|EC:2.7.7.50|Reactome:R-HSA-77081|Reactome:R-HSA-77083									molecular_function											owl:Class	
GO:0031487	biolink:NamedThing	myosin XVII complex	A myosin complex containing one or more class XVII myosin heavy chains and associated light chains.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0046210	biolink:NamedThing	nitric oxide catabolic process	The chemical reactions and pathways resulting in the breakdown of nitric oxide, nitrogen monoxide (NO), a colorless gas only slightly soluble in water.	tmpzr1t_l9r_go_relaxed.owl	nitric oxide catabolism|nitric oxide breakdown|nitric oxide degradation													biological_process											owl:Class	
GO:0038144	biolink:NamedThing	ERBB4:ERBB2 complex	A heterodimeric complex between the tyrosine kinase receptor ERBB2 and a ligand-activated receptor ERBB4. ERBB2, which does not bind any known ligand, is activated through formation of a heterodimer with another ligand-activated ERBB family member such as ERBB4.	tmpzr1t_l9r_go_relaxed.owl	ERBB4:ERBB2 heterodimer|NRGs/EGFLs:ERBB4:ERBB2							bf	2012-03-30T02:24:01Z					cellular_component											owl:Class	
GO:0103028	biolink:NamedThing	murein hydrolase activity	Catalysis of the reaction: a peptidoglycan dimer (generic) = a lipid II + GlcNAc-1,6-anhydro-MurNAc-pentapeptide.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN0-5190									molecular_function											owl:Class	
GO:0033841	biolink:NamedThing	6G-fructosyltransferase activity	Catalysis of the reaction: [1-beta-D-fructofuranosyl-(2->1)-]m+1 alpha-D-glucopyranoside + [1-beta-D-fructofuranosyl-(2->1)-]n+1 alpha-D-glucopyranoside = [1-beta-D-fructofuranosyl-(2->1)-]m alpha-D-glucopyranoside + [1-beta-D-fructofuranosyl-(2->1)-]n+1 beta-D-fructofuranosyl-(2->6)-alpha-D-glucopyranoside (m > 0; n >= 0).	tmpzr1t_l9r_go_relaxed.owl	fructan:fructan 6G-fructosyltransferase activity|6G-FFT|6G-fructotransferase activity|6G-FT|1F-oligo[beta-D-fructofuranosyl-(2->1)-]sucrose 6G-beta-D-fructotransferase activity				MetaCyc:2.4.1.243-RXN|EC:2.4.1.243									molecular_function											owl:Class	
GO:0061740	biolink:NamedThing	protein targeting to lysosome involved in chaperone-mediated autophagy	The targeting of a protein to the lysosome process in which an input protein binds to a chaperone and subsequently to a lysosomal receptor.	tmpzr1t_l9r_go_relaxed.owl								dph	2015-10-21T08:41:29Z					biological_process											owl:Class	
GO:0140294	biolink:NamedThing	NAD DNA ADP-ribosyltransferase activity	Catalysis of the transfer of the ADP-ribose group of NAD+ to a residue in double-stranded DNA.	tmpzr1t_l9r_go_relaxed.owl								pg	2018-11-22T15:45:35Z					molecular_function											owl:Class	
GO:0033488	biolink:NamedThing	cholesterol biosynthetic process via 24,25-dihydrolanosterol	The chemical reactions and pathways resulting in the formation of cholesterol, cholest-5-en-3 beta-ol, via the intermediate 24,25-dihydrolanosterol.	tmpzr1t_l9r_go_relaxed.owl	cholesterol synthesis via 24,25-dihydrolanosterol|cholesterol formation via 24,25-dihydrolanosterol|cholesterol biosynthesis via 24,25-dihydrolanosterol|cholesterol anabolism via 24,25-dihydrolanosterol				MetaCyc:PWY66-3									biological_process											owl:Class	
GO:0047131	biolink:NamedThing	saccharopine dehydrogenase (NAD+, L-glutamate-forming) activity	Catalysis of the reaction: L-saccharopine + H(2)O + NAD(+) = L-glutamate + allysine + H(+) + NADH.	tmpzr1t_l9r_go_relaxed.owl	dehydrogenase, saccharopine (nicotinamide adenine dinucleotide, glutamate-forming)|6-N-(L-1,3-dicarboxypropyl)-L-lysine:NAD+ oxidoreductase (L-glutamate-forming)|NAD+ oxidoreductase (L-2-aminoadipic-delta-semialdehyde and glutamate forming)|N6-(L-1,3-dicarboxypropyl)-L-lysine:NAD+ oxidoreductase (L-glutamate-forming)|saccharopin dehydrogenase activity|aminoadipic semialdehyde synthase activity				EC:1.5.1.9|MetaCyc:1.5.1.9-RXN|RHEA:24520|KEGG_REACTION:R02313|Reactome:R-HSA-70940									molecular_function											owl:Class	
GO:0070772	biolink:NamedThing	PAS complex	A class III phosphatidylinositol 3-kinase complex that contains a phosphatidylinositol-3-phosphate 5-kinase subunit (Fab1p in yeast; PIKfyve in mammals), a kinase activator, and a phosphatase, and may also contain additional proteins; it is involved in regulating the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate. In mammals the complex is composed of PIKFYVE, FIG4 and VAC14. In yeast it is composed of Atg18p, Fig4p, Fab1p, Vac14p and Vac7p.	tmpzr1t_l9r_go_relaxed.owl	autophagy-specific phosphatidylinositol 3-kinase complex							mah	2009-06-30T11:13:32Z					cellular_component											owl:Class	
GO:0102196	biolink:NamedThing	cortisol dehydrogenase activity	Catalysis of the reaction: cortisol + NADP <=> cortisone + NADPH + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-12085|EC:1.1.1.146|RHEA:53484									molecular_function											owl:Class	
GO:1990905	biolink:NamedThing	dinoflagellate peduncle	A small, flexible, finger-like projection of cytoplasm containing an array of microtubles and located near the flagellar pores in some photosynthetic as well as nonphotosynthetic dinoflagellate species. Its functions are not fully understood, but it has been associated with feeding behavior (phagotrophy).	tmpzr1t_l9r_go_relaxed.owl						The term name refers to a taxonomic group to make the label unique with respect to similarly-named anatomical structures.		pr	2015-11-22T10:22:46Z					cellular_component											owl:Class	
GO:0033977	biolink:NamedThing	2-haloacid dehalogenase (configuration-retaining) activity	Catalysis of the reactions: (S)-2-haloacid + H2O = (S)-2-hydroxyacid + halide, and (R)-2-haloacid + H2O = (R)-2-hydroxyacid + halide.	tmpzr1t_l9r_go_relaxed.owl	2-haloalkanoic acid dehalogenase activity|DL-DEXr|2-haloalkanoid acid halidohydrolase activity|DL-2-haloacid dehalogenase activity				MetaCyc:3.8.1.11-RXN|EC:3.8.1.11|RHEA:12072									molecular_function											owl:Class	
GO:0001862	biolink:NamedThing	collectin binding	Binding to a collectin, a member of a group of structurally related pattern recognition molecules characterized by having a carbohydrate recognition domain of the C-type lectin family at the C-terminus and a collagenous domain at the N-terminus.	tmpzr1t_l9r_go_relaxed.owl						Note that collectins include such proteins as mannose-binding lectins (MBL) and surfactant proteins A and D (SP-A and SP-D).								molecular_function											owl:Class	
GO:0045520	biolink:NamedThing	interleukin-24 receptor binding	Binding to an interleukin-24 receptor.	tmpzr1t_l9r_go_relaxed.owl	interleukin-24 receptor ligand|IL-24													molecular_function											owl:Class	
GO:0102255	biolink:NamedThing	neo-lambda-carrahexaose hydrolase activity	Catalysis of the reaction: neo-lambda-carrahexaose + H2O <=> neo-lambda-carratetraose + neo-lambda-carrabiose.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-12428|EC:3.2.1.162									molecular_function											owl:Class	
GO:0102932	biolink:NamedThing	pterocarpan reductase activity	Catalysis of the reaction: H+ + (-)-medicarpin + NADPH = (+)-vestitol + NADP.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-8936									molecular_function											owl:Class	
GO:0017131	biolink:NamedThing	uridine-rich cytoplasmic polyadenylylation element binding	Binding to a U-rich sequence in the 3'-end of nuclear-transcribed mRNAs; required for cytoplasmic polyadenylylation.	tmpzr1t_l9r_go_relaxed.owl	U-rich CPE binding|uridine-rich cytoplasmic polyadenylation element binding													molecular_function											owl:Class	
GO:0036217	biolink:NamedThing	dGTP diphosphatase activity	Catalysis of the reaction: dGTP + H2O = dGMP + diphosphate.	tmpzr1t_l9r_go_relaxed.owl	2'-deoxyguanosine 5'-triphosphate diphosphohydrolase				RHEA:28362|KEGG_REACTION:R01855			bf	2012-05-08T01:47:59Z					molecular_function											owl:Class	
GO:0006219	biolink:NamedThing	deoxyuridine catabolic process	The chemical reactions and pathways resulting in the breakdown of deoxyuridine, 2-deoxyribosyluracil, one of the four major nucleosides of DNA.	tmpzr1t_l9r_go_relaxed.owl	deoxyuridine catabolism|deoxyuridine degradation|deoxyuridine breakdown													biological_process											owl:Class	
GO:0046096	biolink:NamedThing	deoxyuridine metabolic process	The chemical reactions and pathways involving deoxyuridine, 2-deoxyribosyluracil, one of the four major nucleosides of DNA.	tmpzr1t_l9r_go_relaxed.owl	deoxyuridine metabolism													biological_process											owl:Class	
GO:1990555	biolink:NamedThing	mitochondrial oxaloacetate transmembrane transport	The process in which oxaloacetate is transported across a mitochondrial membrane, into or out of the mitochondrion.	tmpzr1t_l9r_go_relaxed.owl								vw	2014-11-19T12:45:37Z					biological_process											owl:Class	
GO:0043985	biolink:NamedThing	histone H4-R3 methylation	The modification of histone H4 by addition of a methyl group to arginine at position 3 of the histone.	tmpzr1t_l9r_go_relaxed.owl	histone H4 R3 methylation|histone H4 methylation at R3|histone H4R3me													biological_process											owl:Class	
GO:0010448	biolink:NamedThing	vegetative meristem growth	The increase in size or mass of a vegetative meristem, a population of undifferentiated cells in a plant shoot which maintains a continuous balance between the production of stem cells and the incorporation of their derivatives into lateral organ primordia.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0090410	biolink:NamedThing	malonate catabolic process	The chemical reactions and pathways resulting in the breakdown of malonate, the propanedioate ion.	tmpzr1t_l9r_go_relaxed.owl								tb	2011-06-10T01:53:43Z					biological_process											owl:Class	
GO:0071061	biolink:NamedThing	alpha6-beta4 integrin-CD151 complex	A protein complex that consists of an alpha6-beta4 integrin complex bound to the tetraspanin CD151.	tmpzr1t_l9r_go_relaxed.owl	ITGA6-ITGB4-CD151 complex							mah	2009-11-03T04:02:37Z					cellular_component											owl:Class	
GO:1905679	biolink:NamedThing	positive regulation of adaptive immune effector response	Any process that activates or increases the frequency, rate or extent of adaptive immune effector response.	tmpzr1t_l9r_go_relaxed.owl	up regulation of adaptive immune effector response|up-regulation of adaptive immune effector response|upregulation of adaptive immune effector response|activation of adaptive immune effector response							tb	2016-11-11T22:25:13Z					biological_process											owl:Class	
GO:0033427	biolink:NamedThing	CAA codon-amino acid adaptor activity	A triplet codon-amino acid adaptor activity that recognizes a CAA codon.	tmpzr1t_l9r_go_relaxed.owl	glutamine tRNA					Note that in the standard genetic code, CAA codes for glutamine.								molecular_function											owl:Class	
GO:0050085	biolink:NamedThing	mannitol 2-dehydrogenase (NADP+) activity	Catalysis of the reaction: D-mannitol + NADP(+) = D-fructose + H(+) + NADPH.	tmpzr1t_l9r_go_relaxed.owl	D-mannitol:NADP+ 2-oxidoreductase activity|NADP-dependent mannitol dehydrogenase activity				MetaCyc:MANNITOL-2-DEHYDROGENASE-NADP+-RXN|RHEA:16765|KEGG_REACTION:R00870|EC:1.1.1.138									molecular_function											owl:Class	
GO:0070326	biolink:NamedThing	very-low-density lipoprotein particle receptor binding	Binding to a very-low-density lipoprotein receptor.	tmpzr1t_l9r_go_relaxed.owl	apolipoprotein E receptor binding|VLDLR binding|VLDL receptor binding|very-low-density lipoprotein receptor binding													molecular_function											owl:Class	
GO:1990566	biolink:NamedThing	I(KACh) inward rectifier potassium channel complex	An inward rectifier potassium channel complex expressed in cardiac muscle, specifically the sinoatrial node and atria, where it controls the heart rate, via regulation by G protein-coupled receptor signalling. In mammals it is composed of GIRK1 (or Kir3.1) and GIRK4 (or Kir3.4) subunits.	tmpzr1t_l9r_go_relaxed.owl	muscarinic potassium channel complex|Kir3.1-Kir3.4 G protein-coupled atrial inward rectifier potassium channel complex|GIRK1-GIRK4 G protein-coupled atrial inward rectifier potassium channel complex					Examples of this are KCNJ3 and KCNJ5 in human (Uniprot symbols P48549 and P48544) in PMID:9765280 inferred from orthology sequence evidence.		ame	2014-11-26T15:16:14Z					cellular_component											owl:Class	
GO:0004095	biolink:NamedThing	carnitine O-palmitoyltransferase activity	Catalysis of the reaction: palmitoyl-CoA + L-carnitine = CoA + L-palmitoylcarnitine.	tmpzr1t_l9r_go_relaxed.owl	CPTi|carnitine palmitoyltransferase II|outer malonyl-CoA inhibitable carnitine palmitoyltransferase activity|acylcarnitine transferase activity|CPT|CPT I (outer membrane carnitine palmitoyl transferase)|carnitine palmitoyltransferase-A|CPT-B|palmitoylcarnitine transferase activity|palmitoyl-CoA:L-carnitine O-palmitoyltransferase activity|carnitine palmitoyltransferase I|L-carnitine palmitoyltransferase activity|carnitine palmitoyltransferase activity|CPT-A|CPTo				MetaCyc:CARNITINE-O-PALMITOYLTRANSFERASE-RXN|EC:2.3.1.21|Reactome:R-HSA-200406|RHEA:12661|Reactome:R-HSA-200410									molecular_function											owl:Class	
GO:0035999	biolink:NamedThing	tetrahydrofolate interconversion	The chemical reactions and pathways by which one-carbon (C1) units are transferred between tetrahydrofolate molecules, to synthesise other tetrahydrofolate molecules.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:PWY-2201|UniPathway:UPA00193			bf	2011-09-02T01:35:49Z					biological_process											owl:Class	
GO:0052835	biolink:NamedThing	inositol-3,4,6-trisphosphate 1-kinase activity	Catalysis of the reaction: 1D-myo-inositol 3,4,6-trisphosphate + ATP = 1D-myo-inositol 1,3,4,6-tetrakisphosphate + ADP + 2 H(+).	tmpzr1t_l9r_go_relaxed.owl	inositol-trisphosphate 1-kinase activity|ATP:1D-myo-inositol-3,4,6-trisphosphate 1-phosphotransferase activity|IP3 1-kinase activity|ins(3,4,6)P(3) 1-kinase activity|inositol 3,4,6-trisphosphate 1-kinase activity|Ins(3,4,6)P3 1-kinase activity|1D-myo-inositol-trisphosphate 1-kinase activity				EC:2.7.1.-|Reactome:R-HSA-1855169			ai	2011-11-29T01:06:01Z					molecular_function											owl:Class	
GO:0035013	biolink:NamedThing	myosuppressin receptor activity	Combining with the peptide myosuppressin to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1905527	biolink:NamedThing	negative regulation of Golgi lumen acidification	Any process that stops, prevents or reduces the frequency, rate or extent of Golgi lumen acidification.	tmpzr1t_l9r_go_relaxed.owl	down regulation of Golgi lumen acidification|inhibition of Golgi lumen acidification|down-regulation of Golgi lumen acidification|downregulation of Golgi lumen acidification							dph	2016-10-05T13:16:33Z					biological_process											owl:Class	
GO:0047572	biolink:NamedThing	3-phosphoglycerate phosphatase activity	Catalysis of the reaction: 3-phospho-D-glycerate + H(2)O = D-glycerate + phosphate.	tmpzr1t_l9r_go_relaxed.owl	D-3-phosphoglycerate phosphatase activity|3-PGA phosphatase activity|D-glycerate-3-phosphate phosphohydrolase activity				RHEA:12412|MetaCyc:3-PHOSPHOGLYCERATE-PHOSPHATASE-RXN|EC:3.1.3.38|KEGG_REACTION:R01511									molecular_function											owl:Class	
GO:0036389	biolink:NamedThing	bacterial pre-replicative complex	A protein-DNA complex that forms at the bacterial oriC during the initial step of DNA replication and allows the origin to become competent, or 'licensed', for replication.	tmpzr1t_l9r_go_relaxed.owl	bacterial pre-RC							bf	2013-06-05T16:41:47Z					cellular_component											owl:Class	
GO:0102312	biolink:NamedThing	4-coumaroyl 2'-hydroxylase activity	Catalysis of the reaction: 4-coumaryl-CoA + 2-oxoglutarate + O2 <=> 2,4-dihydroxycinnamoyl-CoA + succinate + carbon dioxide.	tmpzr1t_l9r_go_relaxed.owl					EC:1.14.11.62|RHEA:57868|MetaCyc:RXN-12963									molecular_function											owl:Class	
GO:0018573	biolink:NamedThing	2-aminophenol 1,6-dioxygenase activity	Catalysis of the reaction: 2-aminophenol + O2 = 2-aminomuconic semialdehyde.	tmpzr1t_l9r_go_relaxed.owl					EC:1.13.11.-|UM-BBD_reactionID:r0305									molecular_function											owl:Class	
GO:0035294	biolink:NamedThing	determination of wing disc primordium	Allocation of embryonic cells to the wing disc founder populations, groups of cells that are committed to contribute to the formation of a wing imaginal disc.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0051907	biolink:NamedThing	S-(hydroxymethyl)glutathione synthase activity	Catalysis of the reaction: S-(hydroxymethyl)glutathione = formaldehyde + glutathione.	tmpzr1t_l9r_go_relaxed.owl	Gfa|glutathione-dependent formaldehyde-activating enzyme activity|S-(hydroxymethyl)glutathione formaldehyde-lyase (glutathione-forming)|S-(hydroxymethyl)glutathione formaldehyde-lyase activity				EC:4.4.1.22|UM-BBD_reactionID:r1145|KEGG_REACTION:R06982|RHEA:22488|MetaCyc:RXN-2961									molecular_function											owl:Class	
GO:0140133	biolink:NamedThing	suppression by symbiont of host cytokine production	Any process in which a symbiont stops, prevents, or reduces the rate or extent of cytokine production by the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	suppression by symbiont of host cytokine secretion|negative regulation by symbiont of host cytokine production	https://github.com/geneontology/go-ontology/issues/14553						pg	2017-11-14T07:07:04Z					biological_process											owl:Class	
GO:0098623	biolink:NamedThing	selenite reductase activity	Catalysis of the reaction: SeO3(2-) + 3NADPH + 5H+ = H2Se + 3NADP+ + 3H2O.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-2408558									molecular_function											owl:Class	
GO:0047468	biolink:NamedThing	phosphoglucomutase (glucose-cofactor) activity	Catalysis of the reaction: glucose-1-phosphate = glucose-6-phosphate; using D-glucose as a cofactor.	tmpzr1t_l9r_go_relaxed.owl	alpha-D-glucose 1,6-phosphomutase (glucose-cofactor)|glucose-1-phosphate phosphotransferase activity				EC:5.4.2.5|MetaCyc:5.4.2.5-RXN									molecular_function											owl:Class	
GO:0033457	biolink:NamedThing	GAU codon-amino acid adaptor activity	A triplet codon-amino acid adaptor activity that recognizes a GAU codon.	tmpzr1t_l9r_go_relaxed.owl	aspartic acid tRNA|GAT codon-amino acid adaptor activity					Note that in the standard genetic code, GAT codes for aspartic acid.								molecular_function											owl:Class	
GO:0002204	biolink:NamedThing	somatic recombination of immunoglobulin genes involved in immune response	The process in which immunoglobulin genes are formed through recombination of the germline genetic elements, also known as immunoglobulin gene segments, within a single locus following the induction of and contributing to an immune response.	tmpzr1t_l9r_go_relaxed.owl	somatic recombination of antibody genes during immune response|somatic recombination of immunoglobulin genes during immune response													biological_process											owl:Class	
GO:0018664	biolink:NamedThing	benzoate 4-monooxygenase activity	Catalysis of the reaction: benzoate + H(+) + NADPH + O(2) = 4-hydroxybenzoate + H(2)O + NADP(+).	tmpzr1t_l9r_go_relaxed.owl	benzoate,NADPH:oxygen oxidoreductase (4-hydroxylating)|benzoate-para-hydroxylase activity|benzoic acid 4-hydroxylase activity|4-hydroxybenzoic hydroxylase activity|benzoate-p-hydroxylase activity|p-hydroxybenzoate hydroxylase activity|benzoate 4-hydroxylase activity|benzoic 4-hydroxylase activity				UM-BBD_reactionID:r0623|RHEA:18033|EC:1.14.14.92|KEGG_REACTION:R01295|MetaCyc:BENZOATE-4-MONOOXYGENASE-RXN									molecular_function											owl:Class	
GO:0004109	biolink:NamedThing	coproporphyrinogen oxidase activity	Catalysis of the reaction: coproporphyrinogen III + 2 H(+) + O(2) = 2 CO(2) + 2 H(2)O + protoporphyrinogen IX.	tmpzr1t_l9r_go_relaxed.owl	coproporphyrinogenase activity|coproporphyrinogen-III oxidase activity|coproporphyrinogen:oxygen oxidoreductase (decarboxylating)|coprogen oxidase activity				KEGG_REACTION:R03220|MetaCyc:RXN0-1461|RHEA:18257|EC:1.3.3.3|Reactome:R-HSA-189421									molecular_function											owl:Class	
GO:1904067	biolink:NamedThing	ascr#2 binding	Binding to ascr#2.	tmpzr1t_l9r_go_relaxed.owl								kmv	2015-03-20T01:39:04Z					molecular_function											owl:Class	
GO:0090304	biolink:NamedThing	nucleic acid metabolic process	Any cellular metabolic process involving nucleic acids.	tmpzr1t_l9r_go_relaxed.owl								tb	2010-04-07T10:18:47Z					biological_process											owl:Class	
GO:0102142	biolink:NamedThing	[dermatan sulfate]-L-iduronyl 2-Osulfotransferase activity	Catalysis of the reaction: 3'-phosphonato-5'-adenylyl sulfate + [dermatan]-alpha-L-iduronate <=> adenosine 3',5'-bismonophosphate + [dermatan-sulfate]-2-O-sulfo-alpha-L-iduronate.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-11561									molecular_function											owl:Class	
GO:0034902	biolink:NamedThing	endosulfan sulfate hydrolase activity	Catalysis of the reaction: endosulfan sulfate + H2O = endosulfan diol + sulfite.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r1387									molecular_function											owl:Class	
GO:0000831	biolink:NamedThing	inositol hexakisphosphate 6-kinase activity	Catalysis of the reaction: ATP + 1D-myo-inositol hexakisphosphate = ADP + 6-diphospho-1D-myo-inositol (1,2,3,4,5)pentakisphosphate.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0018457	biolink:NamedThing	perillyl-alcohol dehydrogenase activity	Catalysis of the reaction: NAD(+) + perillyl alcohol = H(+) + NADH + perillyl aldehyde.	tmpzr1t_l9r_go_relaxed.owl	perillyl alcohol dehydrogenase activity|perillyl-alcohol:NAD+ oxidoreductase activity				UM-BBD_reactionID:r0729|RHEA:10664|MetaCyc:PERILLYL-ALCOHOL-DEHYDROGENASE-RXN|KEGG_REACTION:R03945|EC:1.1.1.144									molecular_function											owl:Class	
GO:0019771	biolink:NamedThing	high-affinity IgG receptor activity	Combining with high affinity with an immunoglobulin of an IgG isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	high affinity Fc receptor activity|high affinity IgG receptor activity													molecular_function											owl:Class	
GO:0098690	biolink:NamedThing	glycinergic synapse	A synapse that uses glycine as a neurotransmitter.	tmpzr1t_l9r_go_relaxed.owl								dos	2017-03-07T14:50:33Z					cellular_component											owl:Class	
GO:0110086	biolink:NamedThing	meiotic actomyosin contractile ring	A cytoskeletal structure composed of actin filaments, myosin, and myosin-associated proteins that forms beneath the plasma membrane of many cells, including animal cells and yeast cells, in a plane perpendicular to the axis of the meiotic spindle, i.e. the cell division plane. Ring contraction is associated with centripetal growth of the membrane that divides the cytoplasm of the two future daughter cells. In animal cells, the meiotic contractile ring is located inside the plasma membrane at the location of the cleavage furrow. In fungal cells, the meiotic contractile ring forms beneath the plasma membrane of the prospore envelope in preparation for completing cytokinesis.	tmpzr1t_l9r_go_relaxed.owl								kmv	2018-02-12T17:26:17Z					cellular_component											owl:Class	
GO:0034804	biolink:NamedThing	benzo(a)pyrene 11,12-epoxidase activity	Catalysis of the reaction: benzo(a)pyrene + O2 = benzo(a)pyrene-11,12-epoxide.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r1119									molecular_function											owl:Class	
GO:0035777	biolink:NamedThing	pronephric distal tubule development	The process whose specific outcome is the progression of the pronephric distal tubule over time, from its formation to the mature structure. A pronephric nephron tubule is an epithelial tube that is part of the pronephros.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-04-04T11:06:01Z					biological_process											owl:Class	
GO:0034025	biolink:NamedThing	D-aspartate ligase activity	Catalysis of the reaction: ATP + D-aspartate + [beta-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)]n = [beta-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-6-N-(beta-D-Asp)-L-Lys-D-Ala-D-Ala)]n + ADP + phosphate.	tmpzr1t_l9r_go_relaxed.owl	aslfm|D-aspartic acid-activating enzyme|D-aspartate:[beta-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)]n ligase (ADP-forming) activity|UDP-MurNAc-pentapeptide:D-aspartate ligase activity				MetaCyc:6.3.1.12-RXN|RHEA:10752|EC:6.3.1.12									molecular_function											owl:Class	
GO:0010609	biolink:NamedThing	mRNA localization resulting in posttranscriptional regulation of gene expression	Any process that modulates the frequency, rate or extent of gene expression after the production of a mRNA transcript by its transport into, or maintainance in, a specific location within the cell.	tmpzr1t_l9r_go_relaxed.owl	posttranscriptional regulation of gene expression by mRNA localisation|posttranscriptional regulation of gene expression by mRNA localization|mRNA localisation resulting in posttranscriptional regulation of gene expression													biological_process											owl:Class	
GO:0051976	biolink:NamedThing	lysine biosynthetic process via alpha-aminoadipate and N2-acetyl-alpha-aminoadipate	The chemical reactions and pathways resulting in the formation of lysine via the intermediates alpha-aminoadipic acid and N2-acetyl-alpha-aminoadipate. This pathway of prokaryotic lysine biosynthesis via alpha-aminoadipate was discovered in the hyper-thermophilic Gram-negative eubacterium Thermus thermophilus. The pathway proceeds as follows: alpha-ketoglutarate is converted to homocitrate, which is metabolized to 3-carboxyhex-2-enedioate and then homoisocitrate. This is then decarboxylated to form alpha-ketoadipate, which is then converted to alpha-aminoadipate. This undergoes acetylation, to form N2-acetyl-alpha-aminoadipate, and is then phosphorylated to give N2-acetyl-alpha-aminoadipyl-delta-phosphate. This is converted to N2-acetyl-alpha-aminoadipate semialdehyde, which is then converted to N2-acetyl-L-lysine. A final deacetylation reaction produces L-lysine.	tmpzr1t_l9r_go_relaxed.owl	lysine biosynthesis via aminoadipic acid and N2-acetyl-alpha-aminoadipate|lysine biosynthetic process via aminoadipic acid and N2-acetyl-alpha-aminoadipate				MetaCyc:PWY-3081									biological_process											owl:Class	
GO:0004018	biolink:NamedThing	N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity	Catalysis of the reaction: N6-(1,2-dicarboxyethyl)AMP = fumarate + AMP.	tmpzr1t_l9r_go_relaxed.owl	adenylosuccinate lyase activity|N6-(1,2-dicarboxyethyl)AMP AMP-lyase activity|6-N-(1,2-dicarboxyethyl)AMP AMP-lyase activity|succino AMP-lyase activity|adenylosuccinase activity				Reactome:R-HSA-73800|RHEA:16853|EC:4.3.2.2|Reactome:R-HSA-73828|KEGG_REACTION:R01083|MetaCyc:AMPSYN-RXN									molecular_function											owl:Class	
GO:0072487	biolink:NamedThing	MSL complex	A histone acetyltransferase complex that catalyzes the acetylation of a histone H4 lysine residue at position 16. In human, it contains the catalytic subunit MOF, and MSL1, MSL2 and MSL3.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-12-10T10:15:11Z					cellular_component											owl:Class	
GO:0102675	biolink:NamedThing	C4-methyltransferase activity	Catalysis of the reaction: 24-ethylidenelophenol + a demethylated methyl acceptor <=> avenasterol + a methylated methyl acceptor.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-4208									molecular_function											owl:Class	
GO:0033191	biolink:NamedThing	macrophomate synthase activity	Catalysis of the reaction: a 2-pyrone + oxalacetate = macrophomate.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0016167	biolink:NamedThing	glial cell-derived neurotrophic factor receptor activity	Combining with glial cell line-derived neurotrophic factor and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	glial cell line-derived neurotrophic factor receptor activity|GDNF receptor activity													molecular_function											owl:Class	
GO:0070966	biolink:NamedThing	nuclear-transcribed mRNA catabolic process, no-go decay	The chemical reactions and pathways resulting in the breakdown of the transcript body of a nuclear-transcribed mRNA with stalls in translation elongation.	tmpzr1t_l9r_go_relaxed.owl	nuclear-transcribed mRNA degradation, no-go decay|no-go decay|nuclear-transcribed mRNA breakdown, no-go decay|nuclear-transcribed mRNA catabolism, no-go decay|no-go mRNA decay							mah	2009-10-01T02:36:22Z					biological_process											owl:Class	
GO:0002222	biolink:NamedThing	stimulatory killer cell immunoglobulin-like receptor signaling pathway	Any series of molecular signals generated as a consequence of binding to a killer cell immunoglobulin-like receptor capable of cellular activation.	tmpzr1t_l9r_go_relaxed.owl	stimulatory KIR signaling pathway|stimulatory killer cell immunoglobulin-like receptor signalling pathway													biological_process											owl:Class	
GO:0070823	biolink:NamedThing	HDA1 complex	A tetrameric histone deacetylase complex that contains a Class II deacetylase catalytic subunit. In S. cerevisiae it is composed of two Hda1p subunits along with Hda2p and Hda3p.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-07-20T04:47:11Z					cellular_component											owl:Class	
GO:0047726	biolink:NamedThing	iron-cytochrome-c reductase activity	Catalysis of the reaction: ferrocytochrome c + Fe3+ = ferricytochrome c + Fe2+.	tmpzr1t_l9r_go_relaxed.owl	iron-cytochrome c reductase activity|ferrocytochrome-c:Fe3+ oxidoreductase activity				MetaCyc:IRON--CYTOCHROME-C-REDUCTASE-RXN|EC:1.9.98.1|RHEA:15617									molecular_function											owl:Class	
GO:0033732	biolink:NamedThing	pyrroloquinoline-quinone synthase activity	Catalysis of the reaction: 6-(2-amino-2-carboxyethyl)-7,8-dioxo-1,2,3,4,7,8-hexahydroquinoline-2,4-dicarboxylate + 3 O(2) = 2 H(2)O + 2 H(2)O(2) + H(+) + pyrroloquinoline quinone.	tmpzr1t_l9r_go_relaxed.owl	6-(2-amino-2-carboxyethyl)-7,8-dioxo-1,2,3,4,5,6,7,8-octahydroquinoline-2,4-dicarboxylate:oxygen oxidoreductase (cyclizing) activity|PqqC				KEGG_REACTION:R07353|RHEA:10692|EC:1.3.3.11|MetaCyc:1.3.3.11-RXN									molecular_function											owl:Class	
GO:0044288	biolink:NamedThing	puncta adhaerentia	A small version of the zonula adherens type junction, characterized by a symmetrical adherent point between two cells.	tmpzr1t_l9r_go_relaxed.owl					NIF_Subcellular:sao257629430			jl	2010-02-04T02:19:38Z					cellular_component											owl:Class	
GO:0047495	biolink:NamedThing	membrane-oligosaccharide glycerophosphotransferase activity	Catalysis of the transfer of a glycerophospho group from one membrane-derived oligosaccharide to another.	tmpzr1t_l9r_go_relaxed.owl	phosphoglycerol cyclase activity|membrane-derived-oligosaccharide-6-(glycerophospho)-D-glucose:membrane-derived-oligosaccharide-D-glucose glycerophosphotransferase activity|periplasmic phosphoglycerotransferase activity				MetaCyc:2.7.8.21-RXN|EC:2.7.8.21									molecular_function											owl:Class	
GO:0062236	biolink:NamedThing	ionocyte differentiation	The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of an ionocyte. Ionocytes are specialized epithelial cells that contribute to osmotic homeostasis.	tmpzr1t_l9r_go_relaxed.owl								dph	2020-04-20T12:30:35Z					biological_process											owl:Class	
GO:0050405	biolink:NamedThing	[acetyl-CoA carboxylase] kinase activity	Catalysis of the reaction: ATP + [acetyl-CoA carboxylase] = ADP + [acetyl-CoA carboxylase] phosphate.	tmpzr1t_l9r_go_relaxed.owl	acetyl-CoA carboxylase kinase 2 activity|acetyl-CoA carboxylase kinase activity|acetyl-CoA carboxylase kinase-3 (AMP-activated) activity|AMPK|acetyl coenzyme A carboxylase kinase (phosphorylating) activity|I-peptide kinase activity|acetyl-CoA carboxylase kinase (cAMP-independent) activity|acetyl-CoA carboxylase bound kinase activity|ACK2|acetyl-CoA carboxylase kinase (AMP-activated) activity|acetyl-CoA carboxylase kinase-2 activity|STK5|ACK3|ATP:acetyl-CoA carboxylase phosphotransferase activity|acetyl-coenzyme A carboxylase kinase activity				RHEA:20333|EC:2.7.11.27|MetaCyc:2.7.11.27-RXN									molecular_function											owl:Class	
GO:0002953	biolink:NamedThing	5'-deoxynucleotidase activity	Catalysis of the reaction:a 2'-deoxyribonucleoside 5'-monophosphate + H20=a 2'-deoxyribonucleoside + phosphate.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0005502	biolink:NamedThing	11-cis retinal binding	Binding to 11-cis retinal, an isomer of retinal that plays an important role in the visual process in most vertebrates. 11-cis retinal combines with opsin in the rods (scotopsin) to form rhodopsin or visual purple. Retinal is one of the three compounds that makes up vitamin A.	tmpzr1t_l9r_go_relaxed.owl	11-cis-retinal binding|11-cis retinaldehyde binding|vitamin A binding													molecular_function											owl:Class	
GO:0034806	biolink:NamedThing	benzo(a)pyrene 11,12-dioxygenase activity	Catalysis of the reaction: benzo(a)pyrene + O2 = benzo(a)pyrene-cis-11,12-dihydrodiol.	tmpzr1t_l9r_go_relaxed.owl					EC:1.13.11.-|UM-BBD_reactionID:r1124									molecular_function											owl:Class	
GO:0090647	biolink:NamedThing	modulation of age-related behavioral decline	Any process that modulates the processes that arise as an organism progresses toward the end of its lifespan that results in a decline in behavioral activities such as locomotory behavior, and learning or memory.	tmpzr1t_l9r_go_relaxed.owl								tb	2015-06-15T12:45:44Z					biological_process											owl:Class	
GO:0070519	biolink:NamedThing	alpha4-beta1 integrin-CD63 complex	A protein complex that consists of an alpha4-beta1 integrin complex bound to membrane protein CD63, a member of the tetraspan family.	tmpzr1t_l9r_go_relaxed.owl	ITGA4-ITGB1-CD63 complex													cellular_component											owl:Class	
GO:0016015	biolink:NamedThing	morphogen activity	Acts as a trigger for a pattern specification process when present at a specific concentration within a gradient.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0102182	biolink:NamedThing	4alpha-carboxy-stigmasta-7,24(241)-dien-3beta-ol dehydrogenase/C4-decarboxylase activity	Catalysis of the reaction: 4alpha-carboxy-stigmasta-7,24(241)-dien-3beta-ol + NAD <=> avenastenone + NADH + carbon dioxide.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-11938									molecular_function											owl:Class	
GO:0102980	biolink:NamedThing	2-butyl-4-hydroxy-5-methyl-3(2H)-furanoneoxidoreductase activity	Catalysis of the reaction: 2-butyl-4-hydroxy-5-methyl-3(2H)-furanone + NADP <=> (2E)-2-butylidene-4-hydroxy-5-methyl-3(2H)-furanone + NADPH + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-9565									molecular_function											owl:Class	
GO:0033921	biolink:NamedThing	capsular-polysaccharide endo-1,3-alpha-galactosidase activity	Catalysis of the random hydrolysis of (1->3)-alpha-D-galactosidic linkages in Aerobacter aerogenes capsular polysaccharide.	tmpzr1t_l9r_go_relaxed.owl	polysaccharide depolymerase activity|aerobacter-capsular-polysaccharide galactohydrolase activity|capsular polysaccharide galactohydrolase activity				EC:3.2.1.87|MetaCyc:3.2.1.87-RXN									molecular_function											owl:Class	
GO:0061468	biolink:NamedThing	karyomere	A membrane-bound intermediate cleavage-stage structure of individual or groups of chromosomes that coalesces and fuses with other karyomeres to form a nucleus during interphase. Karyomere formation occurs in blastomeres undergoing rapid cell division.	tmpzr1t_l9r_go_relaxed.owl								dph	2012-10-22T14:19:29Z					cellular_component											owl:Class	
GO:0120307	biolink:NamedThing	Hechtian strand	An extended membranous thread which firmly connects the plasma membrane to the cell wall during plasmolysis such that the plasma membrane does not separate from the cell wall completely.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/21138			Wikipedia:Hechtian_strand			krc	2021-03-19T20:31:15Z					cellular_component											owl:Class	
GO:0102708	biolink:NamedThing	S-adenosyl-L-methionine:N-methyl-beta-alanine N-methyltransferase activity	Catalysis of the reaction: N-methyl-beta-alanine + S-adenosyl-L-methionine  = H+ + N,N-dimethyl-beta-alanine + S-adenosyl-L-homocysteine.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-6462									molecular_function											owl:Class	
GO:1903514	biolink:NamedThing	release of sequestered calcium ion into cytosol by endoplasmic reticulum	The directed movement of calcium ion from endoplasmic reticulum to cytosol.	tmpzr1t_l9r_go_relaxed.owl	calcium ion transport from endoplasmic reticulum to cytosol							rl	2014-10-02T11:30:34Z					biological_process											owl:Class	
GO:0001635	biolink:NamedThing	calcitonin gene-related peptide receptor activity	Combining with a calcitonin gene-related polypeptide (CGRP) to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	calcitonin gene-related polypeptide receptor activity|CGRP receptor				Wikipedia:CALCRL									molecular_function											owl:Class	
GO:0102542	biolink:NamedThing	aclacinomycin A methylesterase activity	Catalysis of the reaction: aclacinomycin A + H2O <=> 15-demethoxy-aclacinomycin A + methanol + H+.	tmpzr1t_l9r_go_relaxed.owl					EC:3.1.1.95|MetaCyc:RXN-14863									molecular_function											owl:Class	
GO:0052603	biolink:NamedThing	1-chloro-4-nitrosobenzene nitroreductase activity	Catalysis of the reaction: 1-chloro-4-nitrosobenzene + NADPH + H+ = 1-chloro-4-hydroxylaminobenzene + NADP+ + H2O.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-8834|UM-BBD_enzymeID:e0245									molecular_function											owl:Class	
GO:0050331	biolink:NamedThing	thiamine-diphosphate kinase activity	Catalysis of the reaction: ATP + thiamin diphosphate = ADP + thiamin triphosphate.	tmpzr1t_l9r_go_relaxed.owl	TDP kinase activity|ATP:thiamin-diphosphate phosphotransferase activity|thiamin pyrophosphate kinase activity|thiamin diphosphate kinase activity|thiamine diphosphate kinase activity|protein bound thiamin diphosphate:ATP phosphoryltransferase activity|thiamin diphosphate phosphotransferase activity|ATP:thiamine-diphosphate phosphotransferase activity|thiamin-diphosphate kinase activity				MetaCyc:THIAMIN-DIPHOSPHATE-KINASE-RXN|EC:2.7.4.15|Reactome:R-HSA-997381|RHEA:11240									molecular_function											owl:Class	
GO:0070144	biolink:NamedThing	mitochondrial arginyl-tRNA aminoacylation	The process of coupling arginine to arginyl-tRNA in a mitochondrion, catalyzed by arginyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0055077	biolink:NamedThing	gap junction hemi-channel activity	A wide pore channel activity that enables the transport of a solute across a membrane via a gap junction hemi-channel. Two gap junction hemi-channels coupled together form a complete gap junction.	tmpzr1t_l9r_go_relaxed.owl	connexon channel activity													molecular_function											owl:Class	
GO:1904584	biolink:NamedThing	cellular response to polyamine macromolecule	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a polyamine macromolecule stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to polyamine|cellular response to polyamines							sl	2015-08-20T14:35:32Z					biological_process											owl:Class	
GO:0140203	biolink:NamedThing	spermidine import across plasma membrane	The directed movement of spermidine from outside of a cell, across the plasma membrane and into the cytosol.	tmpzr1t_l9r_go_relaxed.owl								pg	2018-02-21T19:10:07Z					biological_process											owl:Class	
GO:0060987	biolink:NamedThing	lipid tube	A macromolecular complex that contains a tube of lipid surrounded by a protein coat.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-01-11T01:54:25Z					cellular_component											owl:Class	
GO:0035444	biolink:NamedThing	nickel cation transmembrane transport	The directed movement of nickel (Ni) cations across a membrane by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	nickel cation membrane transport					Note that this term is not intended for use in annotating lateral movement within membranes.		bf	2010-04-13T09:22:51Z					biological_process											owl:Class	
GO:0004495	biolink:NamedThing	mevaldate reductase activity	Catalysis of the reaction: (R)-mevalonate + acceptor = mevaldate + reduced acceptor.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0035456	biolink:NamedThing	response to interferon-beta	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-beta stimulus. Interferon-beta is a type I interferon.	tmpzr1t_l9r_go_relaxed.owl	response to fiblaferon|response to beta-1 interferon|response to fibroblast interferon|response to interferon beta							bf	2010-04-16T11:06:12Z					biological_process											owl:Class	
GO:0070514	biolink:NamedThing	SRF-myogenin-E12 complex	A transcription factor complex that contains the serum response factor (SRF) and the basic helix-loop-helix proteins myogenin and E12, and is involved in activating transcription of muscle-specific genes.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0042682	biolink:NamedThing	regulation of compound eye cone cell fate specification	Any process that mediates the specification of a cell into a compound eye cone cell.	tmpzr1t_l9r_go_relaxed.owl												GO:0042681		biological_process											owl:Class	
GO:0050609	biolink:NamedThing	phosphonate dehydrogenase activity	Catalysis of the reaction: H(2)O + NAD(+) + phosphonate = 2 H(+) + NADH + phosphate.	tmpzr1t_l9r_go_relaxed.owl	NAD-dependent phosphite dehydrogenas activity|phosphonate:NAD+ oxidoreductase activity|NAD:phosphite oxidoreductase activity|phosphite dehydrogenase activity				KEGG_REACTION:R05746|EC:1.20.1.1|RHEA:13173|MetaCyc:1.20.1.1-RXN|UM-BBD_reactionID:r1055									molecular_function											owl:Class	
GO:0050499	biolink:NamedThing	oxidoreductase activity, acting on phosphorus or arsenic in donors, with NAD(P)+ as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which a phosphorus- or arsenic-containing group acts as a hydrogen or electron donor and reduces a NAD(P)+ to NAD(P)H.	tmpzr1t_l9r_go_relaxed.owl					EC:1.20.1.-									molecular_function											owl:Class	
GO:0071739	biolink:NamedThing	IgD immunoglobulin complex, circulating	A protein complex composed of two identical immunoglobulin heavy chains of the IgD isotype and two identical immunoglobulin light chains, held together by disulfide bonds, and present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.	tmpzr1t_l9r_go_relaxed.owl	IgD antibody					Note that an IgD immunoglobulin complex has the function of antigen binding if a suitable antigen is available.		mah	2010-03-24T01:44:53Z					cellular_component											owl:Class	
GO:0033798	biolink:NamedThing	thyroxine 5-deiodinase activity	Catalysis of the reaction: 3,3',5'-triiodo-L-thyronine + iodide + A + H+ = L-thyroxine + AH2.	tmpzr1t_l9r_go_relaxed.owl	inner ring-deiodinating pathway|iodothyronine 5-deiodinase activity|acceptor:3,3',5'-triiodo-L-thyronine oxidoreductase (iodinating) activity|diiodothyronine 5'-deiodinase activity|type III iodothyronine deiodinase activity|iodothyronine inner ring monodeiodinase activity				MetaCyc:1.97.1.11-RXN|EC:1.21.99.3|RHEA:18897									molecular_function											owl:Class	
GO:0047736	biolink:NamedThing	cellobiose epimerase activity	Catalysis of the reaction: cellobiose = D-glucosyl-D-mannose.	tmpzr1t_l9r_go_relaxed.owl	cellobiose 2-epimerase activity				EC:5.1.3.11|RHEA:23384|MetaCyc:CELLOBIOSE-EPIMERASE-RXN									molecular_function											owl:Class	
GO:1902277	biolink:NamedThing	negative regulation of pancreatic amylase secretion	Any process that stops, prevents or reduces the frequency, rate or extent of pancreatic amylase secretion.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of pancreatic amylase secretion|down regulation of pancreatic amylase secretion|inhibition of pancreatic amylase secretion|downregulation of pancreatic amylase secretion							bf	2013-07-03T12:15:26Z					biological_process											owl:Class	
GO:0050262	biolink:NamedThing	ribosylnicotinamide kinase activity	Catalysis of the reaction: N-ribosylnicotinamide + ATP = ADP + 2 H(+) + nicotinamide mononucleotide.	tmpzr1t_l9r_go_relaxed.owl	ATP:N-ribosylnicotinamide 5'-phosphotransferase activity|nicotinamide riboside kinase activity|ribosylnicotinamide kinase (phosphorylating)				KEGG_REACTION:R02324|Reactome:R-HSA-8869633|MetaCyc:RIBOSYLNICOTINAMIDE-KINASE-RXN|EC:2.7.1.22|Reactome:R-HSA-8869627|RHEA:14017							GO:0000816		molecular_function											owl:Class	
GO:0000412	biolink:NamedThing	histone peptidyl-prolyl isomerization	The modification of a histone by cis-trans isomerization of a proline residue.	tmpzr1t_l9r_go_relaxed.owl	histone proline isomerization													biological_process											owl:Class	
GO:0052795	biolink:NamedThing	exo-alpha-(2->6)-sialidase activity	Catalysis of the hydrolysis of alpha-(2->6)-glycosidic linkages of terminal sialic residues in substrates.	tmpzr1t_l9r_go_relaxed.owl	exo-alpha-(2,6)-sialidase activity|exo-alpha-2,6-sialidase activity				EC:3.2.1.18									molecular_function											owl:Class	
GO:0071962	biolink:NamedThing	mitotic sister chromatid cohesion, centromeric	The cell cycle process in which centromeres of sister chromatids are joined during mitosis.	tmpzr1t_l9r_go_relaxed.owl	sister chromatid cohesion at centromere at mitosis|mitotic sister chromatid cohesion at centromere|centromeric mitotic sister chromatin cohesion							mah	2011-06-02T11:24:17Z					biological_process											owl:Class	
GO:0019688	biolink:NamedThing	purine deoxyribonucleoside interconversion	The chemical reactions and pathways by which a purine deoxyribonucleoside is synthesized from another purine deoxyribonucleoside.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0001325	biolink:NamedThing	formation of extrachromosomal circular DNA	Excision from the chromosome and circularization of a region of chromosomal DNA, generally, but not always, via homologous recombination between direct tandem repeats.	tmpzr1t_l9r_go_relaxed.owl	assembly of extrachromosomal circular DNA													biological_process											owl:Class	
GO:0071434	biolink:NamedThing	cell chemotaxis to angiotensin	The directed movement of a motile cell in response to the presence of angiotensin.	tmpzr1t_l9r_go_relaxed.owl	angiotensin mediated chemotaxis|angiotensin-mediated cell chemotaxis							mah	2009-12-16T11:07:15Z					biological_process											owl:Class	
GO:0102733	biolink:NamedThing	typhasterol C-23 hydroxylase activity	Catalysis of the reaction: typhasterol + O2 + a reduced electron acceptor = castasterone + H2O + an oxidized electron acceptor.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-719									molecular_function											owl:Class	
GO:0046559	biolink:NamedThing	alpha-glucuronidase activity	Catalysis of the reaction: an alpha-D-glucuronoside + H2O = an alcohol + D-glucuronate.	tmpzr1t_l9r_go_relaxed.owl	alpha-glucosiduronase activity|alpha-D-glucosiduronate glucuronohydrolase activity				MetaCyc:3.2.1.139-RXN|EC:3.2.1.139|RHEA:20005									molecular_function											owl:Class	
GO:1990111	biolink:NamedThing	spermatoproteasome complex	A proteasome specifically found in mammalian testis. Contains the proteasome activator PA200 in the regulatory particle, and beta1i, beta2i, beta5i and/or alpha4s in the core (20S) subunit. Beta1i, beta2i and beta5i are inducible catalytic subunits, closely related to beta1, beta2 and beta5. Alpha4s is a sperm-specific 20S subunit, but unlike other alternative 20S subunits alpha4s lies in the outer alpha-ring and lacks catalytic activity.	tmpzr1t_l9r_go_relaxed.owl								sp	2013-05-31T11:56:52Z					cellular_component											owl:Class	
GO:0070513	biolink:NamedThing	death domain binding	Binding to a death domain of a protein. The death domain (DD) is a homotypic protein interaction module composed of a bundle of six alpha-helices. DD bind each other forming oligomers. Some DD-containing proteins are involved in the regulation of apoptosis and inflammation through their activation of caspases and NF-kappaB.	tmpzr1t_l9r_go_relaxed.owl						For binding to the death effector domain, consider instead the term 'death effector domain binding ; GO:0035877'.								molecular_function											owl:Class	
GO:0045051	biolink:NamedThing	protein insertion into ER membrane by internal uncleaved signal-anchor sequence	A process of protein insertion into the endoplasmic reticulum (ER) membrane in which signal anchor sequences function as both ER signal sequences and membrane anchor sequences.	tmpzr1t_l9r_go_relaxed.owl	protein insertion into ER membrane, internal uncleaved signal-anchor sequence mediated|protein insertion into endoplasmic reticulum membrane by internal uncleaved signal-anchor sequence|protein-endoplasmic reticulum insertion by internal uncleaved signal-anchor sequence|internal uncleaved signal-anchor sequence mediated protein insertion into ER membrane|protein-ER insertion by internal uncleaved signal-anchor sequence													biological_process											owl:Class	
GO:0061923	biolink:NamedThing	(2S,3R,6S,9S)-(-)-protoillud-7-ene synthase activity	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = diphosphate + (2S,3R,6S,9S)-(-)-protoillud-7-ene.	tmpzr1t_l9r_go_relaxed.owl	protoillud-7-ene synthase activity							dph	2017-08-02T15:48:21Z					molecular_function											owl:Class	
GO:0048135	biolink:NamedThing	female germ-line cyst formation	Formation of a group of interconnected cells derived from a single female gonial founder cell.	tmpzr1t_l9r_go_relaxed.owl	female germline cyst formation													biological_process											owl:Class	
GO:1990166	biolink:NamedThing	protein localization to site of double-strand break	Any process in which a protein is transported to, or maintained at, a region of a chromosome at which a DNA double-strand break has occurred.	tmpzr1t_l9r_go_relaxed.owl	protein localisation to site of double-strand break|protein localization to double-strand break site|protein localization to site of DSB							mah	2013-08-08T11:27:00Z					biological_process											owl:Class	
GO:0060494	biolink:NamedThing	inductive mesenchymal-endodermal cell signaling	Any process that mediates the transfer of information from a mesenchymal cell to an endodermal cell changing the fate of the endodermal cell.	tmpzr1t_l9r_go_relaxed.owl	inductive mesenchymal-endodermal cell signalling													biological_process											owl:Class	
GO:0030985	biolink:NamedThing	high molecular weight kininogen binding	Binding to a kininogen of high molecular mass.	tmpzr1t_l9r_go_relaxed.owl	HK binding|HMW kininogen binding													molecular_function											owl:Class	
GO:0006295	biolink:NamedThing	nucleotide-excision repair, DNA incision, 3'-to lesion	The endonucleolytic cleavage of the damaged strand of DNA 3' to the site of damage. The incision occurs at the junction of single-stranded DNA and double-stranded DNA that is formed when the DNA duplex is unwound. The incision precedes the incision formed 5' to the site of damage.	tmpzr1t_l9r_go_relaxed.owl	nucleotide-excision repair, DNA incision, 3' to lesion													biological_process											owl:Class	
GO:0034017	biolink:NamedThing	trans-2-decenoyl-acyl-carrier-protein isomerase activity	Catalysis of the reaction: trans-dec-2-enoyl-[acyl-carrier protein] = cis-dec-3-enoyl-[acyl-carrier protein].	tmpzr1t_l9r_go_relaxed.owl	trans-2-cis-3-decenoyl-ACP isomerase activity|decenoyl-acyl-carrier-protein delta2-trans-delta3-cis-isomerase activity|trans-2,cis-3-decenoyl-ACP isomerase activity|FabM|trans-2, cis-3 decenoyl-[acyl-carrier-protein] isomerase activity|beta-hydroxydecanoyl thioester dehydrase activity|trans-2, cis-3 decenoyl-ACP isomerase activity|trans-2-decenoyl-ACP isomerase activity				RHEA:23568|EC:5.3.3.14|MetaCyc:5.3.3.14-RXN							GO:0043832		molecular_function											owl:Class	
GO:0044750	biolink:NamedThing	high-affinity nickel cation transmembrane transporter activity	Catalysis of the high-affinity transfer of nickel (Ni) cations from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-11-20T15:15:59Z					molecular_function											owl:Class	
GO:0102136	biolink:NamedThing	3-epi-6-deoxocathasterone C-23 hydroxylase activity	Catalysis of the reaction: H+ + 3-epi-6-deoxocathasterone + reduced (NADPH-hemoprotein reducdtase) + O2 = 6=deoxotyphasterol + oxidized (NADPH-hemoprotein reductase) + H2O.	tmpzr1t_l9r_go_relaxed.owl					RHEA:27321|MetaCyc:RXN-11531|EC:1.14.14.147									molecular_function											owl:Class	
GO:0018028	biolink:NamedThing	peptidyl-lysine myristoylation	The myristoylation of peptidyl-lysine to form peptidyl-N6-myristoyl-L-lysine.	tmpzr1t_l9r_go_relaxed.owl	peptidyl-lysine myristylation				RESID:AA0078									biological_process											owl:Class	
GO:0021754	biolink:NamedThing	facial nucleus development	The process whose specific outcome is the progression of the facial nucleus over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0009569	biolink:NamedThing	chloroplast starch grain	Plant storage body for amylose and amylopectin, 1-100um in diameter, and located in chloroplasts. Also contains small amounts of enzymes, amino acids, lipids and nucleic acids. The shape of the grain varies widely amongst species, but is often spherical or disk-shaped.	tmpzr1t_l9r_go_relaxed.owl	chloroplast starch granule													cellular_component											owl:Class	
GO:0032299	biolink:NamedThing	ribonuclease H2 complex	A protein complex that possesses ribonuclease H activity, in which the catalytic subunit is a member of the RNase H2 (or HII) class. For example, in Saccharomyces the complex contains Rnh201p, Rnh202p and Rnh203p.	tmpzr1t_l9r_go_relaxed.owl	RNase H2 complex													cellular_component											owl:Class	
GO:0035366	biolink:NamedThing	negative regulation of thymine transport	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of thymine, 5-methyluracil, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of 5-methyluracil transport							bf	2010-03-11T10:23:42Z					biological_process											owl:Class	
GO:0044373	biolink:NamedThing	cytokinin binding	Binding to a cytokinin, any of a class of adenine-derived compounds that can function in plants as growth regulators.	tmpzr1t_l9r_go_relaxed.owl								jl	2011-12-01T03:42:10Z					molecular_function											owl:Class	
GO:0120327	biolink:NamedThing	telopode	A telopode is a plasma membrane bounded cell projection that is present on a telocyte and is tens to hundreds of microns long. Telopodes form a labyrinthine system communicating through gap junctions.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/21973						krc	2021-08-16T16:45:21Z					cellular_component											owl:Class	
GO:0099077	biolink:NamedThing	histone-dependent DNA binding	DNA-binding activity that is dependent on binding to a histone.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0090581	biolink:NamedThing	protein-phosphocysteine-mannosylglycerate-phosphotransferase system transporter activity	Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein S-phosphocysteine + mannosylglycerate(out) = protein cysteine + mannosylglycerate phosphate(in).	tmpzr1t_l9r_go_relaxed.owl								tb	2014-06-04T16:22:31Z					molecular_function											owl:Class	
GO:0034008	biolink:NamedThing	R-linalool synthase activity	Catalysis of the reaction: geranyl diphosphate + H(2)O = (R)-linalool + diphosphate.	tmpzr1t_l9r_go_relaxed.owl	geranyl-diphosphate diphosphate-lyase [(3R)-linalool-forming] activity|(3R)-linalool synthase activity|(-)-3R-linalool synthase activity				MetaCyc:4.2.3.26-RXN|RHEA:15809|KEGG_REACTION:R07632|EC:4.2.3.26									molecular_function											owl:Class	
GO:0031912	biolink:NamedThing	oral apparatus	Complex basket- or funnel-like structure used by the cell to collect food and channel it to the cytostome; includes specialized sub-structures made up of closely-spaced cilia and underlying basal bodies and fibrillar systems.	tmpzr1t_l9r_go_relaxed.owl						Note that this term refers to a subcellular structure characteristic of ciliate protozoans, and should not be confused with oral anatomical structures of multicellular animals.								cellular_component											owl:Class	
GO:0097618	biolink:NamedThing	dinoflagellate sulcal notch	A dinoflagellate sulcus that extends all the way to the posterior end of the cell (also known as antapex). The presence of a sulcal notch makes the dinoflagellate hypocone appear bilobed.	tmpzr1t_l9r_go_relaxed.owl	dinoflagellate sulcus notch|sulcal notch					The term name refers to a taxonomic group to make the label unique with respect to similarly-named anatomical structures. Also, the ventral (front) side of a dinoflagellate cell is the one where the sulcus is located (as opposed to the dorsal (back) side). The term 'sulcal notch' appears mostly in older literature; more recently, indication of a bilobed hypocone is used to express the same.		pr	2014-06-27T16:28:49Z					cellular_component											owl:Class	
GO:0097612	biolink:NamedThing	dinoflagellate sulcus	A cell surface furrow that occurs on the ventral side of a dinoflagellate cell. It partially houses the longitudinal flagellum. The sulcus intersects with the cingulum on the ventral side of a dinoflagellate cell.	tmpzr1t_l9r_go_relaxed.owl	longitudinal groove|longitudinal furrow|sulcus					The term name refers to a taxonomic group to make the label unique with respect to similarly-named anatomical structures. Also, the ventral (front) side of a dinoflagellate cell is the one where the sulcus is located (as opposed to the dorsal (back) side).		pr	2014-06-09T11:31:05Z					cellular_component											owl:Class	
GO:0018268	biolink:NamedThing	GPI anchor biosynthetic process via N-glycyl-glycosylphosphatidylinositolethanolamine	The chemical reactions and pathways resulting in the formation of a C-terminal peptidyl-glycine ethanolamide-linked glycosylphosphatidylinositol (GPI) anchor following hydrolysis of a glycyl-peptide bond in the carboxy-terminal region of a membrane-associated protein.	tmpzr1t_l9r_go_relaxed.owl	GPI anchor synthesis via N-glycyl-glycosylphosphatidylinositolethanolamine|GPI anchor formation via N-glycyl-glycosylphosphatidylinositolethanolamine|GPI anchor anabolism via N-glycyl-glycosylphosphatidylinositolethanolamine				RESID:AA0161									biological_process											owl:Class	
GO:0031590	biolink:NamedThing	wybutosine metabolic process	The chemical reactions and pathways involving wybutosine, 3H-imidazo[1,2-alpha]purine-7-butanoic acid, 4,9-dihydro- alpha-[(methoxycarbonyl)amino]- 4,6-dimethyl-9-oxo- 3-beta-D-ribofuranosyl methyl ester, a modified nucleoside found in some tRNA molecules.	tmpzr1t_l9r_go_relaxed.owl	yW metabolic process|yW metabolism|wybutosine metabolism													biological_process											owl:Class	
GO:0039720	biolink:NamedThing	virogenic stroma	A nuclear viral factory formed by Baculoviruses. A vesicular structure in which virions are assembled.	tmpzr1t_l9r_go_relaxed.owl	VS							bf	2013-12-19T15:45:32Z					cellular_component											owl:Class	
GO:0071128	biolink:NamedThing	alpha5-beta1 integrin-osteopontin complex	A protein complex that consists of an alpha5-beta1 integrin complex bound to osteopontin.	tmpzr1t_l9r_go_relaxed.owl	ITGA5-ITGB1-SPP1 complex							mah	2009-11-13T02:24:43Z					cellular_component											owl:Class	
GO:0031882	biolink:NamedThing	type 5 somatostatin receptor binding	Binding to a type 5 somatostatin receptor.	tmpzr1t_l9r_go_relaxed.owl	type 5 somatostatin receptor ligand													molecular_function											owl:Class	
GO:0018702	biolink:NamedThing	1,1-dichloro-2,2-bis(4-chlorophenyl)ethene dehalogenase activity	Catalysis of the reaction: 1,1-dichloro-2,2-bis(4-chlorophenyl)ethene + H+ + 2 e- = Cl- + 1-chloro-2,2-bis(4-chlorophenyl)ethene. 1,1-dichloro-2,2-bis(4-chlorophenyl)ethene is also known as DDE; 1-chloro-2,2-bis(4-chlorophenyl)ethene is also known as DDMU.	tmpzr1t_l9r_go_relaxed.owl	DDE dehalogenase activity|1,1-dichloro-2,2-bis(4-chlorophenyl)ethylene dehalogenase activity				EC:1.97.1.-|UM-BBD_reactionID:r0440									molecular_function											owl:Class	
GO:0044220	biolink:NamedThing	host cell perinuclear region of cytoplasm	The host cell cytoplasm situated near, or occurring around, the host nucleus.	tmpzr1t_l9r_go_relaxed.owl								jl	2009-11-12T02:58:13Z					cellular_component											owl:Class	
GO:0034580	biolink:NamedThing	4-methyloctanoyl-CoA dehydrogenase activity	Catalysis of the reaction: 4-methyloctanoyl-CoA = 4-methyloct-2-enoyl-CoA + 2 H+ + 2 e-.	tmpzr1t_l9r_go_relaxed.owl					EC:1.3.99.-|UM-BBD_reactionID:r0924									molecular_function											owl:Class	
GO:0039606	biolink:NamedThing	suppression by virus of host translation initiation	Any process in which a virus prevents or reduces the frequency, rate or extent of host translation initiation, the host process preceding formation of the peptide bond between the first two amino acids of a protein.	tmpzr1t_l9r_go_relaxed.owl								bf	2012-07-05T04:44:10Z					biological_process											owl:Class	
GO:0018020	biolink:NamedThing	peptidyl-glutamic acid methylation	The addition of a methyl group to a glutamic acid residue in a protein.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0031789	biolink:NamedThing	G protein-coupled acetylcholine receptor binding	Binding to a G protein-coupled acetylcholine receptor.	tmpzr1t_l9r_go_relaxed.owl	M2 muscarinic acetylcholine receptor ligand|G-protein coupled acetylcholine receptor binding|M1 muscarinic acetylcholine receptor ligand|M5 muscarinic acetylcholine receptor binding|M3 muscarinic acetylcholine receptor binding|muscarinic acetylcholine receptor binding|M1 muscarinic acetylcholine receptor binding|M2 muscarinic acetylcholine receptor binding|M5 muscarinic acetylcholine receptor ligand|M4 muscarinic acetylcholine receptor ligand|M4 muscarinic acetylcholine receptor binding|muscarinic acetylcholine receptor ligand|M3 muscarinic acetylcholine receptor ligand											GO:0031790|GO:0031794|GO:0031793|GO:0031791|GO:0031792		molecular_function											owl:Class	
GO:0071570	biolink:NamedThing	cement gland development	The process whose specific outcome is the progression of the cement gland over time, from its formation to the mature structure. The cement gland is a simple mucus-secreting organ positioned at the anterior of amphibious embryos. The cement gland attaches the newly hatched embryo to a support before the hatchling can swim well or feed.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-01-20T04:31:04Z					biological_process											owl:Class	
GO:1990537	biolink:NamedThing	mitotic spindle polar microtubule	Any of the mitotic spindle microtubules that come from each pole and overlap at the spindle midzone.	tmpzr1t_l9r_go_relaxed.owl								vw	2014-11-14T15:32:38Z					cellular_component											owl:Class	
GO:0019033	biolink:NamedThing	viral tegument	A structure lying between the capsid and envelope of a virus, varying in thickness and often distributed asymmetrically.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Viral_tegument									cellular_component											owl:Class	
GO:0009016	biolink:NamedThing	succinyldiaminopimelate transaminase activity	Catalysis of the reaction: 2-oxoglutarate + N-succinyl-LL-2,6-diaminopimelate = L-2-succinylamino-6-oxopimelate + L-glutamate.	tmpzr1t_l9r_go_relaxed.owl	succinyldiaminopimelate aminotransferase activity|N-succinyl-L-2,6-diaminoheptanedioate:2-oxoglutarate aminotransferase activity|N-succinyl-L-diaminopimelic glutamic transaminase activity|succinyldiaminopimelate transferase activity				KEGG_REACTION:R04475|MetaCyc:SUCCINYLDIAMINOPIMTRANS-RXN|EC:2.6.1.17|RHEA:11960									molecular_function											owl:Class	
GO:0004048	biolink:NamedThing	anthranilate phosphoribosyltransferase activity	Catalysis of the reaction: N-(5-phospho-beta-D-ribosyl)anthranilate + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + anthranilate.	tmpzr1t_l9r_go_relaxed.owl	phosphoribosyl-anthranilate pyrophosphorylase activity|anthranilate 5-phosphoribosylpyrophosphate phosphoribosyltransferase activity|anthranilate-PP-ribose-P phosphoribosyltransferase activity|phosphoribosyl-anthranilate diphosphorylase activity|anthranilate phosphoribosylpyrophosphate phosphoribosyltransferase activity|phosphoribosylanthranilate transferase activity|phosphoribosylanthranilate pyrophosphorylase activity|N-(5-phospho-D-ribosyl)-anthranilate:diphosphate phospho-alpha-D-ribosyltransferase activity|PRT				RHEA:11768|MetaCyc:PRTRANS-RXN|EC:2.4.2.18|KEGG_REACTION:R01073									molecular_function											owl:Class	
GO:0051148	biolink:NamedThing	negative regulation of muscle cell differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of muscle cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	downregulation of muscle cell differentiation|down-regulation of muscle cell differentiation|inhibition of muscle cell differentiation|down regulation of muscle cell differentiation													biological_process											owl:Class	
GO:0046067	biolink:NamedThing	dGDP catabolic process	The chemical reactions and pathways resulting in the breakdown of dGDP, deoxyguanosine diphosphate, (2'-deoxyguanosine 5'-diphosphate).	tmpzr1t_l9r_go_relaxed.owl	dGDP catabolism|dGDP degradation|dGDP breakdown													biological_process											owl:Class	
GO:0018080	biolink:NamedThing	peptidyl-tryptophan bromination	The bromination of peptidyl-tryptophan, to form peptidyl-L-6'-bromotryptophan.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0179									biological_process											owl:Class	
GO:0004676	biolink:NamedThing	3-phosphoinositide-dependent protein kinase activity	Phosphatidylinositol-3-phosphate-dependent catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein.	tmpzr1t_l9r_go_relaxed.owl	PDK activity|phosphatidylinositol-3-phosphate protein kinase activity				Reactome:R-HSA-437195	This reaction requires the presence of a phosphatidylinositol-3-phosphate.								molecular_function											owl:Class	
GO:0018663	biolink:NamedThing	2,6-dihydroxypyridine 3-monooxygenase activity	Catalysis of the reaction: 2,6-dihydroxypyridine + H(+) + NADH + O(2) = 2,3,6-trihydroxypyridine + H(2)O + NAD(+).	tmpzr1t_l9r_go_relaxed.owl	2,6-dihydroxypyridine oxidase activity|2,6-dihydroxypyridine,NADH:oxygen oxidoreductase (3-hydroxylating)				KEGG_REACTION:R04130|UM-BBD_reactionID:r0479|MetaCyc:1.14.13.10-RXN|RHEA:16917|EC:1.14.13.10									molecular_function											owl:Class	
GO:0046866	biolink:NamedThing	tetraterpenoid transport	The directed movement of tetraterpenoids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Tetraterpenoids are terpenoids with eight isoprene units.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0102329	biolink:NamedThing	hentriaconta-3,6,9,12,19,22,25,28-octaene-16-one-15-oyl-CoA reductase activity	Catalysis of the reaction: 16-hydroxy-hentriaconta-3,6,9,12,19,22,25,28-octaene-15-oyl-CoA + NADP <=> hentriaconta-3,6,9,12,19,22,25,28-octaene-16-one-15-oyl-CoA + NADPH + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-13251									molecular_function											owl:Class	
GO:0047374	biolink:NamedThing	methylumbelliferyl-acetate deacetylase activity	Catalysis of the reaction: 4-methylumbelliferyl acetate + H(2)O = 4-methylumbelliferone + acetate + H(+).	tmpzr1t_l9r_go_relaxed.owl	4-methylumbelliferyl-acetate acylhydrolase activity|esterase D activity				RHEA:12208|MetaCyc:3.1.1.56-RXN|EC:3.1.1.56|KEGG_REACTION:R04141									molecular_function											owl:Class	
GO:0008236	biolink:NamedThing	serine-type peptidase activity	Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine).	tmpzr1t_l9r_go_relaxed.owl	serine protease activity				Reactome:R-HSA-1461993|Reactome:R-HSA-2022383|Reactome:R-HSA-3132753|Reactome:R-HSA-6801766									molecular_function											owl:Class	
GO:0021646	biolink:NamedThing	vagus nerve formation	The process that gives rise to the vagus nerve. This process pertains to the initial formation of a structure from unspecified parts. This nerve is primarily sensory but also has visceromotor components. It originates in the brain stem and controls many autonomic functions of the heart, lungs, stomach, pharynx, larynx, trachea, esophagus and other gastrointestinal tract components. It controls some motor functions such as speech. The sensory branches mediate sensation from the pharynx, larynx, thorax and abdomen; it also innervates taste buds in the epiglottis.	tmpzr1t_l9r_go_relaxed.owl	CN X biosynthesis|CN X formation													biological_process											owl:Class	
GO:0019664	biolink:NamedThing	mixed acid fermentation	The anaerobic chemical reactions and pathways resulting in the breakdown of glucose into ethanol, lactate, formate, succinate, and acetate, yielding energy in the form of ATP.	tmpzr1t_l9r_go_relaxed.owl	glucose catabolic process to mixed acids|glucose fermentation to mixed acids				Wikipedia:Mixed_acid_fermentation									biological_process											owl:Class	
GO:0140207	biolink:NamedThing	tripeptide import across plasma membrane	The directed movement of a tripeptide from outside of a cell, across the plasma membrane and into the cytosol.	tmpzr1t_l9r_go_relaxed.owl								pg	2018-02-22T15:49:55Z					biological_process											owl:Class	
GO:0050032	biolink:NamedThing	L-rhamnonate dehydratase activity	Catalysis of the reaction: L-rhamnonate = 2-dehydro-3-deoxy-L-rhamnonate + H(2)O.	tmpzr1t_l9r_go_relaxed.owl	L-rhamnonate hydro-lyase activity|L-rhamnonate hydro-lyase (2-dehydro-3-deoxy-L-rhamnonate-forming)				EC:4.2.1.90|MetaCyc:L-RHAMNONATE-DEHYDRATASE-RXN|RHEA:23080|KEGG_REACTION:R03774									molecular_function											owl:Class	
GO:0042030	biolink:NamedThing	ATPase inhibitor activity	Binds to and stops, prevents or reduces an ATP hydrolysis activity.	tmpzr1t_l9r_go_relaxed.owl	adenosinetriphosphatase inhibitor	https://github.com/geneontology/go-ontology/issues/20955												molecular_function											owl:Class	
GO:0036486	biolink:NamedThing	ventral trunk neural crest cell migration	The movement of trunk neural crest cells from the neural tube, travelling ventrally through the anterior half of each sclerotome. Trunk neural crest cells that remain in the sclerotome form the dorsal root ganglia containing the sensory neurons. Trunk neural crest cells that continue more ventrally form the sympathetic ganglia, the adrenal medulla, and the nerve clusters surrounding the aorta.	tmpzr1t_l9r_go_relaxed.owl	trunk NCC migration within somite|trunk NCC migration through anterior sclerotome|ventral trunk NCC migration							bf	2014-08-26T15:30:16Z					biological_process											owl:Class	
GO:0070612	biolink:NamedThing	histone methyltransferase activity (H2A-R3 specific)	Catalysis of the reaction: S-adenosyl-L-methionine + (histone H2A)-arginine (position 3) = S-adenosyl-L-homocysteine + (histone H2A)-N-methyl-arginine (position 3). This reaction is the addition of a methyl group to arginine at position 3 of histone H2A.	tmpzr1t_l9r_go_relaxed.owl	histone-arginine N-methyltransferase activity (H2A-R3 specific)|histone methylase activity (H2A-R3 specific)							mah	2009-04-29T02:06:45Z					molecular_function											owl:Class	
GO:0061574	biolink:NamedThing	ASAP complex	A protein complex involved in regulation of mRNA processing and apoptosis. It binds to RNA in a sequence-independent manner and is recruited to the EJC prior to or during the splicing process. In humans the core proteins are RNPS1, SAP18 and ACIN1.	tmpzr1t_l9r_go_relaxed.owl								dph	2013-10-08T13:09:16Z					cellular_component											owl:Class	
GO:0010408	biolink:NamedThing	fasciclin-like arabinogalactan protein metabolic process	The chemical reactions and pathways involving the cell wall arabinogalactan II glycoprotein variant which contains both an arabinogalactan protein (AGP) motif and a fasciclin domain.	tmpzr1t_l9r_go_relaxed.owl	fasciclin-like arabinogalactan protein metabolism													biological_process											owl:Class	
GO:0010405	biolink:NamedThing	arabinogalactan protein metabolic process	The chemical reactions and pathways involving a cell wall arabinogalactan II glycoprotein, which is composed of a group of core protein of highly varying length and domain complexity. These are O-glycosylated at one or more hydroxyproline residues by arabinogalactan (AG) type II groups, which consist of (1->3)-beta-galactan and (1->6)-beta-linked galactan chains connected to each other by (1->3,1->6)-linked branch points, O-3 and O-6 positions substituted with terminal arabinosyl residues. Also, rhamnose, fucose, glucuronic and galacturonic acid can be present in the glycan structures.	tmpzr1t_l9r_go_relaxed.owl	arabinogalactan protein metabolism													biological_process											owl:Class	
GO:0106177	biolink:NamedThing	cyclic-GMP-AMP hydrolase activity	Catalysis of the reaction: cyclic GMP-AMP + 2 H2O = AMP + GMP.	tmpzr1t_l9r_go_relaxed.owl					RHEA:58808			hjd	2019-03-07T21:06:24Z					molecular_function											owl:Class	
GO:0098735	biolink:NamedThing	positive regulation of the force of heart contraction	Any process that increases the force of heart muscle contraction.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0034131	biolink:NamedThing	regulation of toll-like receptor 1 signaling pathway	Any process that modulates the frequency, rate, or extent of toll-like receptor 1 signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	regulation of toll-like receptor 1 signalling pathway|regulation of TLR1 signaling pathway													biological_process											owl:Class	
GO:0072703	biolink:NamedThing	cellular response to methyl methanesulfonate	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methyl methanesulfonate (MMS) stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to MMS							mah	2012-04-11T03:04:18Z					biological_process											owl:Class	
GO:0072702	biolink:NamedThing	response to methyl methanesulfonate	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methyl methanesulfonate (MMS) stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to MMS							mah	2012-04-11T03:04:12Z					biological_process											owl:Class	
GO:0042426	biolink:NamedThing	choline catabolic process	The chemical reactions and pathways resulting in the breakdown of choline (2-hydroxyethyltrimethylammonium), an amino alcohol that occurs widely in living organisms as a constituent of certain types of phospholipids and in the neurotransmitter acetylcholine.	tmpzr1t_l9r_go_relaxed.owl	choline catabolism|choline degradation|choline breakdown													biological_process											owl:Class	
GO:1905069	biolink:NamedThing	allantois development	The process whose specific outcome is the progression of an allantois over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl	allantoic bud development							cls	2016-03-21T15:18:21Z					biological_process											owl:Class	
GO:0001758	biolink:NamedThing	retinal dehydrogenase activity	Catalysis of the reaction: retinal + NAD+ + H2O = retinoate + NADH. Acts on both 11-trans and 13-cis forms of retinal.	tmpzr1t_l9r_go_relaxed.owl	retinal:NAD+ oxidoreductase activity|cytosolic retinal dehydrogenase activity				RHEA:16177|EC:1.2.1.36|MetaCyc:RETINAL-DEHYDROGENASE-RXN|Reactome:R-HSA-5696101|Reactome:R-HSA-5362522									molecular_function											owl:Class	
GO:0004692	biolink:NamedThing	cGMP-dependent protein kinase activity	cGMP dependent catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein.	tmpzr1t_l9r_go_relaxed.owl	PKG 1alpha|ATP:protein phosphotransferase (cGMP-dependent) activity|PKG|PKG II|STK23|cGMP-dependent protein kinase ibeta activity|3':5'-cyclic GMP-dependent protein kinase activity|guanosine 3':5'-cyclic monophosphate-dependent protein kinase activity|PKG 1beta				MetaCyc:2.7.11.12-RXN|Reactome:R-HSA-418549|Reactome:R-HSA-1497853|Reactome:R-HSA-1475422|Reactome:R-HSA-418442|EC:2.7.11.12	This reaction requires the presence of cGMP.								molecular_function											owl:Class	
GO:0004690	biolink:NamedThing	cyclic nucleotide-dependent protein kinase activity	cNMP-dependent catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein.	tmpzr1t_l9r_go_relaxed.owl						This reaction requires the presence of a cyclic nucleotide.								molecular_function											owl:Class	
GO:0031478	biolink:NamedThing	myosin VIII complex	A myosin complex containing a dimer of class VIII myosin heavy chains and associated light chains. Myosin VIII is predicted to be dimeric, and contain an unusual 100-190 residue N-terminal extension prior to their motor domains, 3-4 IQ motifs, a short region (~70 residues) of predicted alpha-helical coiled coil and a C-terminal domain.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0009731	biolink:NamedThing	detection of sucrose stimulus	The series of events in which a sucrose stimulus is received by a cell and converted into a molecular signal.	tmpzr1t_l9r_go_relaxed.owl	perception of sucrose stimulus													biological_process											owl:Class	
GO:0070194	biolink:NamedThing	synaptonemal complex disassembly	The controlled breakdown of a synaptonemal complex.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0051717	biolink:NamedThing	inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity	Catalysis of the reaction: inositol-1,3,4,5-tetrakisphosphate + H2O = inositol-1,4,5-trisphosphate + phosphate.	tmpzr1t_l9r_go_relaxed.owl	inositol 1,3,4,5-tetrakisphosphate 3-phosphomonoesterase activity|inositol (1,3,4,5)-tetrakisphosphate 3-phosphatase activity|inositol 1,3,4,5-tetrakisphosphate-5-phosphomonoesterase activity				Reactome:R-HSA-1855205|MetaCyc:3.1.3.62-RXN|Reactome:R-HSA-1855200									molecular_function											owl:Class	
GO:0002414	biolink:NamedThing	immunoglobulin transcytosis in epithelial cells	The process of transporting immunoglobulin, via transcytosis, from one side of an epithelial cell to the other.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0071054	biolink:NamedThing	alpha9-beta1 integrin-ADAM3 complex	A protein complex that consists of an alpha9-beta1 integrin complex bound to the transmembrane metallopeptidase ADAM3.	tmpzr1t_l9r_go_relaxed.owl	ITGA9-ITGB1-ADAM3 complex							mah	2009-11-03T03:59:02Z					cellular_component											owl:Class	
GO:0004657	biolink:NamedThing	proline dehydrogenase activity	Catalysis of the reaction: L-proline + acceptor = (S)-1-pyrroline-5-carboxylate + reduced acceptor.	tmpzr1t_l9r_go_relaxed.owl	L-proline:acceptor oxidoreductase activity|L-proline dehydrogenase activity|L-proline:(acceptor) oxidoreductase activity				MetaCyc:RXN-7181|Reactome:R-HSA-6784224|Reactome:R-HSA-70670|RHEA:23784|EC:1.5.99.8|Reactome:R-HSA-8955817									molecular_function											owl:Class	
GO:0140441	biolink:NamedThing	protein-cysteine S-arachidonoyltransferase activity	Catalysis of the transfer of an arachidonoyl (systematic name, (5Z,8Z,11Z,14Z)-eicosatetraenoyl) group to a sulfur atom on the cysteine of a protein molecule, in the reaction: in the reaction: (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + L-cysteinyl-[protein] = CoA + S-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-L-cysteinyl-[protein].	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/18882			RHEA:59748			pg	2020-03-11T09:56:24Z					molecular_function											owl:Class	
GO:0102596	biolink:NamedThing	cytochrome P450 dependent ent-sandaracopimaradiene 3-hydroxylase activity	Catalysis of the reaction: ent-sandaracopimara-8(14),15-diene + NADPH + H+ + O2 <=> ent-sandaracopimaradien-3beta-ol + NADP + H2O.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-15379|RHEA:41464|EC:1.14.14.70									molecular_function											owl:Class	
GO:0010653	biolink:NamedThing	negative regulation of cell communication by chemical coupling	Any process that decreases the frequency, rate or extent of cell communication via chemical coupling. Cell communication by chemical coupling is the process that mediates signaling interactions between one cell and another cell by the transfer of small, water-soluble molecules or metabolites between their adjacent cytoplasms via intercellular protein channels.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0042137	biolink:NamedThing	sequestering of neurotransmitter	The process of binding or confining a neurotransmitter such that it is separated from other components of a biological system.	tmpzr1t_l9r_go_relaxed.owl	retention of neurotransmitter|sequestration of neurotransmitter|neurotransmitter storage|neurotransmitter retention|neurotransmitter biosynthesis and storage|storage of neurotransmitter|neurotransmitter biosynthetic process and storage|neurotransmitter sequestration													biological_process											owl:Class	
GO:0051018	biolink:NamedThing	protein kinase A binding	Binding to a protein kinase A.	tmpzr1t_l9r_go_relaxed.owl	PKA binding|protein kinase A anchoring activity					Note that this term is a direct child of 'protein binding ; GO:0005515' because it encompasses binding to either the catalytic or regulatory subunit of protein kinase A, and the latter does not have kinase activity.								molecular_function											owl:Class	
GO:0048453	biolink:NamedThing	sepal formation	The process that gives rise to the sepal. This process pertains to the initial formation of a structure from unspecified parts.	tmpzr1t_l9r_go_relaxed.owl												GO:0048423		biological_process											owl:Class	
GO:0033222	biolink:NamedThing	xylose binding	Binding to the D- or L-enantiomer of xylose.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0050402	biolink:NamedThing	xylono-1,4-lactonase activity	Catalysis of the reaction: D-xylono-1,4-lactone + H2O = D-xylonate.	tmpzr1t_l9r_go_relaxed.owl	xylonolactonase activity|xylono-g-lactonase activity|D-xylono-1,4-lactone lactonohydrolase activity				RHEA:18341|MetaCyc:XYLONO-14-LACTONASE-RXN|EC:3.1.1.68									molecular_function											owl:Class	
GO:0035479	biolink:NamedThing	angioblast cell migration from lateral mesoderm to midline	The directed movement of angioblasts from the lateral mesoderm to the midline which occurs as part of the formation of the early midline vasculature.	tmpzr1t_l9r_go_relaxed.owl								bf	2010-04-23T10:38:05Z					biological_process											owl:Class	
GO:0102805	biolink:NamedThing	codeine O-demethylase activity	Catalysis of the reaction: codeine + 2-oxoglutarate + O2 <=> morphine + formaldehyde + succinate + carbon dioxide.	tmpzr1t_l9r_go_relaxed.owl					RHEA:27413|EC:1.14.11.32|MetaCyc:RXN-8152									molecular_function											owl:Class	
GO:0106212	biolink:NamedThing	centromere detachment from spindle pole body involved in meiotic chromosome organization	The cell cycle process in which centromeres dissociate from the spindle pole body, contributing to the rearrangement of chromosomes into the orientation characteristic of meiotic prophase I.	tmpzr1t_l9r_go_relaxed.owl	centromere detachment from SPB involved in meiotic chromosome organization|centromere detachment from spindle pole body involved in chromosome organization involved in meiotic cell cycle							hjd	2019-06-25T18:28:39Z					biological_process											owl:Class	
GO:0033982	biolink:NamedThing	3-dehydro-L-gulonate-6-phosphate decarboxylase activity	Catalysis of the reaction: 3-dehydro-L-gulonate 6-phosphate + H(+) = L-xylulose 5-phosphate + CO(2).	tmpzr1t_l9r_go_relaxed.owl	KGPDC|UlaD|3-keto-L-gulonate 6-phosphate decarboxylase activity|3-dehydro-L-gulonate-6-phosphate carboxy-lyase (L-xylulose-5-phosphate-forming) activity|SgaH|SgbH|3-dehydro-L-gulonate-6-phosphate carboxy-lyase activity				EC:4.1.1.85|MetaCyc:RXN0-705|RHEA:14353|KEGG_REACTION:R07125									molecular_function											owl:Class	
GO:0090497	biolink:NamedThing	mesenchymal cell migration	The orderly movement of a mesenchymal cell from one site to another, often during the development of a multicellular organism.	tmpzr1t_l9r_go_relaxed.owl								tb	2012-10-17T12:08:17Z					biological_process											owl:Class	
GO:1990196	biolink:NamedThing	MacAB-TolC complex	The MacAB-TolC complex is a macrolide transporter complex found in E.coli and related gram-negative bacteria. Its transport activity is specific to macrolide compounds containing 14- and 15-membered lactones. It consists of the dimeric inner membrane ATPase MacB, the hexameric, periplasmic membrane fusion protein MacA and the trimeric outer membrane factor TolC.	tmpzr1t_l9r_go_relaxed.owl	macrolide transporter MacAB-TolC complex							bhm	2013-09-23T11:29:28Z					cellular_component											owl:Class	
GO:0050617	biolink:NamedThing	15,16-dihydrobiliverdin:ferredoxin oxidoreductase activity	Catalysis of the reaction: 15,16-dihydrobiliverdin + oxidized ferredoxin = biliverdin IXa + reduced ferredoxin.	tmpzr1t_l9r_go_relaxed.owl	PebA				EC:1.3.7.2|RHEA:10168|MetaCyc:1.3.7.2-RXN									molecular_function											owl:Class	
GO:0044180	biolink:NamedThing	filamentous growth of a unicellular organism	The process in which a unicellular organism grows in a threadlike, filamentous shape.	tmpzr1t_l9r_go_relaxed.owl								jl	2009-09-25T10:16:01Z					biological_process											owl:Class	
GO:0050086	biolink:NamedThing	mannitol 2-dehydrogenase activity	Catalysis of the reaction: D-mannitol + NAD+ = D-fructose + NADH.	tmpzr1t_l9r_go_relaxed.owl	D-mannitol dehydrogenase activity|D-mannitol:NAD+ 2-oxidoreductase activity				EC:1.1.1.67|RHEA:12084|MetaCyc:MANNITOL-2-DEHYDROGENASE-RXN									molecular_function											owl:Class	
GO:0061911	biolink:NamedThing	amphisome-lysosome fusion	The process in which amphisomes fuse with a vacuole (yeast) or lysosome (e.g. mammals and insects). In the case of yeast, inner membrane-bounded structures (autophagic bodies) appear in the vacuole. Fusion provides an acidic environment and digestive function to the interior of the amphisome.	tmpzr1t_l9r_go_relaxed.owl								dph	2017-07-05T18:54:52Z					biological_process											owl:Class	
GO:0046269	biolink:NamedThing	toluene-4-sulfonate catabolic process	The chemical reactions and pathways resulting in the breakdown of toluene-4-sulfonate, 4-methylbenzenesulfonate, the anion of sulfonic acid attached to a methylbenzene molecule.	tmpzr1t_l9r_go_relaxed.owl	toluene-4-sulfonate breakdown|4-toluenesulfonate catabolism|toluene-4-sulphonate catabolic process|toluene-4-sulfonate catabolism|toluene-4-sulfonate degradation|4-toluenesulfonate catabolic process|toluene-4-sulphonate catabolism													biological_process											owl:Class	
GO:0071134	biolink:NamedThing	alpha9-beta1 integrin-thrombospondin-1 complex	A protein complex that consists of an alpha9-beta1 integrin complex bound to thrombospondin-1.	tmpzr1t_l9r_go_relaxed.owl	ITGA9-ITGB1-THBS1 complex							mah	2009-11-13T02:29:07Z					cellular_component											owl:Class	
GO:0015950	biolink:NamedThing	purine nucleotide interconversion	The chemical reactions and pathways by which a purine nucleotide is synthesized from another purine nucleotide.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0030506	biolink:NamedThing	ankyrin binding	Binding to ankyrin, a 200 kDa cytoskeletal protein that attaches other cytoskeletal proteins to integral membrane proteins.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0006025	biolink:NamedThing	galactosaminoglycan biosynthetic process	The chemical reactions and pathways resulting in the formation of galactosaminoglycans, any of a group of polysaccharides that contain amino sugars derived from the galactose.	tmpzr1t_l9r_go_relaxed.owl	galactosaminoglycan synthesis|galactosaminoglycan biosynthesis|galactosaminoglycan anabolism|galactosaminoglycan formation													biological_process											owl:Class	
GO:0097093	biolink:NamedThing	polyacyltrehalose biosynthetic process	The chemical reactions and pathways resulting in the formation of polyacyltrehalose, a pentaacylated, trehalose-based glycolipid.	tmpzr1t_l9r_go_relaxed.owl	polyacyltrehalose formation|polyacyltrehalose synthesis|polyacyltrehalose biosynthesis|polyacyltrehalose anabolism							pr	2011-07-05T02:01:08Z					biological_process											owl:Class	
GO:0097092	biolink:NamedThing	polyacyltrehalose metabolic process	The chemical reactions and pathways involving polyacyltrehalose, a pentaacylated, trehalose-based glycolipid.	tmpzr1t_l9r_go_relaxed.owl	polyacyltrehalose metabolism							pr	2011-07-05T01:58:28Z					biological_process											owl:Class	
GO:0033406	biolink:NamedThing	UCC codon-amino acid adaptor activity	A triplet codon-amino acid adaptor activity that recognizes a UCC codon.	tmpzr1t_l9r_go_relaxed.owl	serine tRNA|TCC codon-amino acid adaptor activity					Note that in the standard genetic code, TCC codes for serine.								molecular_function											owl:Class	
GO:0008226	biolink:NamedThing	tyramine receptor activity	Combining with the biogenic amine tyramine to initiate a change in cell activity. Tyramine is a sympathomimetic amine derived from tyrosine with an action resembling that of epinephrine.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0102800	biolink:NamedThing	caffeoyl-CoA:pelargonidin-3,5-diglucoside-6''-O-acyltransferase activity	Catalysis of the reaction: anthocyanidin 3,5-di-O-beta-D-glucoside + caffeoyl-CoA = pelargonidin 3-O-(6-O-caffeoyl-beta-D-glucoside) 5-O-beta-D-glucoside + coenzyme A.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-8138									molecular_function											owl:Class	
GO:0033855	biolink:NamedThing	nicotianamine aminotransferase activity	Catalysis of the reaction: 2-oxoglutarate + nicotianamine = 3''-deamino-3''-oxonicotianamine + L-glutamate.	tmpzr1t_l9r_go_relaxed.owl	NAAT-II|nicotianamine transaminase activity|NAAT-I|NAAT-III|NAAT|nicotianamine:2-oxoglutarate aminotransferase activity				KEGG_REACTION:R07277|MetaCyc:2.6.1.80-RXN|EC:2.6.1.80|RHEA:22104									molecular_function											owl:Class	
GO:0072370	biolink:NamedThing	histone H2A-S121 phosphorylation	The modification of histone H2A by the addition of an phosphate group to a serine residue at position 121 of the histone.	tmpzr1t_l9r_go_relaxed.owl	histone H2AS121 phosphorylation|histone H2A phosphorylation at S121							mah	2010-11-16T03:42:52Z					biological_process											owl:Class	
GO:0034618	biolink:NamedThing	arginine binding	Binding to 2-amino-5-(carbamimidamido)pentanoic acid.	tmpzr1t_l9r_go_relaxed.owl	Arg binding|aminopentanoic acid binding													molecular_function											owl:Class	
GO:0048067	biolink:NamedThing	cuticle pigmentation	Establishment of a pattern of pigment in the cuticle of an organism.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0052064	biolink:NamedThing	induction by symbiont of defense-related host reactive oxygen species production	The activation by a symbiont of the production of reactive oxygen species as part of the defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	activation by symbiont of defense-related host ROI production|activation by symbiont of defense-related host oxidative burst|activation by symbiont of defense-related host respiratory burst|induction by organism of defense-related reactive oxygen species production in other organism involved in symbiotic interaction|activation by symbiont of defense-related host metabolic burst|up-regulation by symbiont of defense-related host reactive oxygen species production|upregulation by symbiont of defense-related host reactive oxygen species production|induction by symbiont of defense-related host reactive oxidative species production|induction by symbiont of defense-related host oxidative burst|activation by symbiont of defense-related host reactive oxygen species production|stimulation by symbiont of defense-related host reactive oxygen species production|positive regulation by symbiont of defense-related host reactive oxygen species production|activation by symbiont of defense-related host reactive oxidative species production|activation by symbiont of defense-related host reactive oxygen intermediate production|positive regulation by organism of defense-related reactive oxygen species production in other organism involved in symbiotic interaction|induction by symbiont of defense-related reactive oxygen species production in other organism involved in symbiotic interaction|induction by symbiont of defense-related host AOS production|induction by symbiont of defense-related host metabolic burst|activation by symbiont of defense-related host ROS production|up regulation by symbiont of defense-related host reactive oxygen species production|induction by symbiont of defense-related host active oxygen species production											GO:0052348|GO:0052369|GO:0052264		biological_process											owl:Class	
GO:1902521	biolink:NamedThing	response to etoposide	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an etoposide stimulus.	tmpzr1t_l9r_go_relaxed.owl						Note that this term is in the subset of terms that should not be used for direct manual annotation of gene products. It was created to be used for cross-referencing by other ontologies. Direct annotations to this term may be amended during annotation QC.		dw	2013-12-02T09:44:22Z					biological_process											owl:Class	
GO:0120155	biolink:NamedThing	MIH complex	A trimeric complex involved in cytokinesis. Proposed to bridge actomyosin ring contraction and septum synthesis in yeast, resulting in the coordination of these processes, and leading to plasma membrane ingression and fusion. In the yeast Saccharomyces cerevisiae this complex consists of Mlc1p, Iqg1p and Hof1p proteins.	tmpzr1t_l9r_go_relaxed.owl	Mlc1p-Iqg1p-Hof1p complex							krc	2018-05-01T17:50:23Z					cellular_component											owl:Class	
GO:0047006	biolink:NamedThing	17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity	Catalysis of the reaction: NAD(P)+ + 17-alpha,20-alpha-dihydroxypregn-4-en-3-one = NAD(P)H + H+ + 17-alpha-hydroxyprogesterone.	tmpzr1t_l9r_go_relaxed.owl	20alpha-hydroxy steroid dehydrogenase activity|20alpha-HSD|20alpha-hydroxysteroid dehydrogenase|20alpha-HSDH|20alpha-hydroxysteroid:NAD(P)+ 20-oxidoreductase activity				MetaCyc:1.1.1.149-RXN|EC:1.1.1.149									molecular_function											owl:Class	
GO:1902552	biolink:NamedThing	negative regulation of catalase activity	Any process that stops, prevents or reduces the frequency, rate or extent of catalase activity.	tmpzr1t_l9r_go_relaxed.owl	downregulation of equilase activity|inhibition of heme catalase activity|down regulation of optidase activity|down-regulation of catalase reaction|inhibition of CAT|inhibition of manganese catalase activity|down-regulation of hydrogen-peroxide:hydrogen-peroxide oxidoreductase activity|negative regulation of bacterial catalase-peroxidase activity|downregulation of manganese catalase activity|down-regulation of catalase-peroxidase activity|negative regulation of CAT|negative regulation of optidase activity|inhibition of caperase activity|inhibition of hydrogen-peroxide:hydrogen-peroxide oxidoreductase activity|down regulation of catalase-peroxidase activity|down regulation of CAT|inhibition of bacterial catalase-peroxidase activity|inhibition of catalase activity|inhibition of equilase activity|downregulation of optidase activity|inhibition of haem catalase activity|down-regulation of catalase activity|down regulation of equilase activity|down regulation of catalase activity|negative regulation of hydrogen-peroxide:hydrogen-peroxide oxidoreductase activity|inhibition of optidase activity|negative regulation of catalase reaction|negative regulation of manganese catalase activity|inhibition of catalase reaction|down regulation of caperase activity|downregulation of catalase reaction|downregulation of bacterial catalase-peroxidase activity|down-regulation of CAT|downregulation of haem catalase activity|down-regulation of caperase activity|downregulation of CAT|down regulation of manganese catalase activity|down regulation of haem catalase activity|down regulation of hydrogen-peroxide:hydrogen-peroxide oxidoreductase activity|negative regulation of heme catalase activity|negative regulation of caperase activity|downregulation of caperase activity|down-regulation of equilase activity|down-regulation of bacterial catalase-peroxidase activity|downregulation of catalase activity|negative regulation of haem catalase activity|inhibition of catalase-peroxidase activity|downregulation of hydrogen-peroxide:hydrogen-peroxide oxidoreductase activity|down-regulation of heme catalase activity|downregulation of catalase-peroxidase activity|down regulation of catalase reaction|negative regulation of catalase-peroxidase activity|down regulation of heme catalase activity|down-regulation of manganese catalase activity|negative regulation of equilase activity|down-regulation of optidase activity|down regulation of bacterial catalase-peroxidase activity|down-regulation of haem catalase activity|downregulation of heme catalase activity							tb	2013-12-04T21:55:55Z					biological_process											owl:Class	
GO:0034004	biolink:NamedThing	germacradienol synthase activity	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate + H2O = (1E,4S,5E,7R)-germacra-1(10),5-dien-11-ol + diphosphate.	tmpzr1t_l9r_go_relaxed.owl	2-trans,6-trans-farnesyl-diphosphate diphosphate-lyase [(1E,4S,5E,7R)-germacra-1(10),5-dien-11-ol-forming] activity				KEGG_REACTION:R07647|MetaCyc:RXN-8648|RHEA:22436|EC:4.2.3.22									molecular_function											owl:Class	
GO:0019261	biolink:NamedThing	1,4-dichlorobenzene catabolic process	The chemical reactions and pathways resulting in the breakdown of 1,4-dichlorobenzene (p-dichlorobenzene or paramoth), a derivative of benzene with two chlorine atoms attached at opposite positions on the ring.	tmpzr1t_l9r_go_relaxed.owl	1,4-dichlorobenzene catabolism|1,4-dichlorobenzene breakdown|1,4-dichlorobenzene degradation				MetaCyc:14DICHLORBENZDEG-PWY									biological_process											owl:Class	
GO:0015614	biolink:NamedThing	ABC-type D-xylose transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + D-xylose(out) -> ADP + phosphate + D-xylose(in).	tmpzr1t_l9r_go_relaxed.owl	D-xylose porter activity|D-xylose-importing ATPase activity|ATPase-coupled D-xylose transmembrane transporter activity				EC:7.5.2.10|RHEA:29899									molecular_function											owl:Class	
GO:0033824	biolink:NamedThing	alternansucrase activity	Catalysis of the transfer of an alpha-D-glucosyl residue from sucrose to alternately the 6-position and the 3-position of the non-reducing terminal residue of an alpha-D-glucan, thus producing a glucan having alternating alpha-1,6- and alpha-1,3-linkages.	tmpzr1t_l9r_go_relaxed.owl	sucrose:1,6-, 1,3-alpha-D-glucan 3-alpha- and 6-alpha-D-glucosyltransferase activity|sucrose:1,6(1,3)-alpha-D-glucan 6(3)-alpha-D-glucosyltransferase activity|sucrose-1,6(3)-alpha-glucan 6(3)-alpha-glucosyltransferase activity				MetaCyc:2.4.1.140-RXN|EC:2.4.1.140									molecular_function											owl:Class	
GO:0005364	biolink:NamedThing	maltose:proton symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: maltose(out) + H+(out) = maltose(in) + H+(in).	tmpzr1t_l9r_go_relaxed.owl	maltose permease|hydrogen/maltose transporter activity|maltose:hydrogen symporter activity													molecular_function											owl:Class	
GO:0018402	biolink:NamedThing	protein-chondroitin sulfate linkage via chondroitin sulfate D-glucuronyl-D-galactosyl-D-galactosyl-D-xylosyl-L-serine	Chondroitin sulfate components are covalently linked to a core glycoprotein via O-glycosidic linkages between xylose and serine residues.	tmpzr1t_l9r_go_relaxed.owl	protein-chondroitin sulphate linkage via chondroitin sulphate D-glucuronyl-D-galactosyl-D-galactosyl-D-xylosyl-L-serine				RESID:AA0208									biological_process											owl:Class	
GO:0070824	biolink:NamedThing	SHREC complex	A histone deacetylase complex that contains a core of four proteins -- Clr1, Clr2, Clr3, and Mit1 in fission yeast -- and localizes to all heterochromatic regions in the genome as well as some euchromatic sites. The complex is involved in regulating nucleosome positioning to assemble higher-order chromatin structures.	tmpzr1t_l9r_go_relaxed.owl	Snf2/Hdac repressive complex|Snf2/HDAC containing repressor complex	https://github.com/geneontology/go-ontology/issues/20938						mah	2009-07-20T05:02:12Z					cellular_component											owl:Class	
GO:0052798	biolink:NamedThing	beta-galactoside alpha-2,3-sialyltransferase activity	Catalysis of the transfer of sialyl residues alpha-2,3-linked to a beta galactosyl residue on the donor to form an alpha-2,3 linkage to a terminal beta galactosyl residue on the acceptor.	tmpzr1t_l9r_go_relaxed.owl	trans-sialidase activity													molecular_function											owl:Class	
GO:0033778	biolink:NamedThing	7alpha-hydroxycholest-4-en-3-one 12alpha-hydroxylase activity	Catalysis of the reaction: 7alpha-hydroxycholest-4-en-3-one + H(+) + NADPH + O(2) = 7alpha,12alpha-dihydroxycholest-4-en-3-one + H(2)O + NADP(+).	tmpzr1t_l9r_go_relaxed.owl	7alpha-hydroxy-4-cholesten-3-one 12alpha-monooxygenase activity|7alpha-hydroxycholest-4-en-3-one,NADPH:oxygen oxidoreductase (12alpha-hydroxylating) activity|CYP12|HCO 12alpha-hydroxylase activity|sterol 12alpha-hydroxylase activity				RHEA:10504|MetaCyc:1.14.13.95-RXN|Reactome:R-HSA-193845|KEGG_REACTION:R04826|EC:1.14.14.139|Reactome:R-HSA-193709|Reactome:R-HSA-192157									molecular_function											owl:Class	
GO:1905594	biolink:NamedThing	resveratrol binding	Binding to resveratrol.	tmpzr1t_l9r_go_relaxed.owl						(5-(aziridin-1-yl)-2,4-dinitrobenzamide		pga	2016-10-25T15:23:37Z					molecular_function											owl:Class	
GO:0120201	biolink:NamedThing	cone photoreceptor disc membrane	Stack of disc membranes located inside a cone photoreceptor outer segment, and containing densely packed molecules of opsin photoreceptor proteins that traverse the lipid bilayer. Cone disc membranes arise as evaginations of the ciliary membrane during the development of the cone outer segment and remain contiguous with the ciliary membrane.	tmpzr1t_l9r_go_relaxed.owl								krc	2019-05-07T23:17:43Z					cellular_component											owl:Class	
GO:0043769	biolink:NamedThing	Tpg-containing telomere binding complex	A complex composed of four polypeptides, a telomere-protecting terminal protein (Tpg), a telomere-associated protein (Tap), DNA polymerase (PolA) and topoisomerase I (TopA), that functions in the replication of the telomeric regions of linear chromosomes, plasmids and circular replicons of some bacterial species.	tmpzr1t_l9r_go_relaxed.owl	telomere complex													cellular_component											owl:Class	
GO:0031734	biolink:NamedThing	CCR9 chemokine receptor binding	Binding to a CCR9 chemokine receptor.	tmpzr1t_l9r_go_relaxed.owl	CCR9 chemokine receptor ligand													molecular_function											owl:Class	
GO:1903259	biolink:NamedThing	exon-exon junction complex disassembly	The disaggregation of an exon-exon junction complex into its constituent components.	tmpzr1t_l9r_go_relaxed.owl	EJC disassembly							sart	2014-08-06T09:44:06Z					biological_process											owl:Class	
GO:0006433	biolink:NamedThing	prolyl-tRNA aminoacylation	The process of coupling proline to prolyl-tRNA, catalyzed by prolyl-tRNA synthetase. The prolyl-tRNA synthetase is a  class-II synthetase. The activated amino acid is transferred to the 3'-OH group of a methionine-accetping tRNA.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0006335	biolink:NamedThing	DNA replication-dependent chromatin assembly	The formation of nucleosomes on newly replicated DNA, coupled to strand elongation.	tmpzr1t_l9r_go_relaxed.owl	DNA replication-dependent nucleosome assembly	https://github.com/geneontology/go-ontology/issues/22130												biological_process											owl:Class	
GO:0000121	biolink:NamedThing	glycerol-1-phosphatase activity	Catalysis of the reaction: glycerol-1-phosphate + H2O = glycerol + phosphate.	tmpzr1t_l9r_go_relaxed.owl	glycerol 3-phosphate phosphohydrolase activity|glycerol-3-phosphate phosphatase activity|alpha-glycerophosphatase activity|alpha-glycerol phosphatase activity|glycerol-1-phosphate phosphohydrolase activity|glycerol 3-phosphatase activity				MetaCyc:GLYCEROL-1-PHOSPHATASE-RXN|EC:3.1.3.21|RHEA:11476									molecular_function											owl:Class	
GO:0071564	biolink:NamedThing	npBAF complex	A SWI/SNF-type complex that is found in neural stem or progenitor cells, and in human contains actin and proteins encoded by the ARID1A/BAF250A or ARID1B/BAF250B, SMARCD1/BAF60A, SMARCD3/BAF60C, SMARCA2/BRM/BAF190B, SMARCA4/BRG1/BAF190A, SMARCB1/BAF47, SMARCC1/BAF155, SMARCE1/BAF57, SMARCC2/BAF170, PHF10/BAF45A, ACTL6A/BAF53A genes. The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-01-20T03:33:42Z					cellular_component											owl:Class	
GO:0018000	biolink:NamedThing	N-terminal peptidyl-tyrosine acetylation	The acetylation of the N-terminal tyrosine of proteins to form the derivative N-acetyl-L-tyrosine.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0053									biological_process											owl:Class	
GO:1905222	biolink:NamedThing	atrioventricular canal morphogenesis	The developmental process by which an atrioventricular canal is generated and organized.	tmpzr1t_l9r_go_relaxed.owl	AVC morphogenesis|ependymal canal morphogenesis|atrial canal morphogenesis|AV canal morphogenesis|canalis atrioventricularis morphogenesis|atrio-ventricular canal morphogenesis							rl	2016-06-07T09:09:51Z					biological_process											owl:Class	
GO:0043715	biolink:NamedThing	2,3-diketo-5-methylthiopentyl-1-phosphate enolase activity	Catalysis of the reaction: 2,3-diketo-5-methylthiopentyl-1-phosphate = H+ + 2-hydroxy 3-keto-5-methylthiopentenyl-1-phosphate. 2,3-diketo-5-methylthiopentyl-1-phosphate is also known as DK-MTP-1-P, and 2-hydroxy 3-keto-5-methylthiopentenyl-1-phosphate as HK-MTPenyl-1-P.	tmpzr1t_l9r_go_relaxed.owl	E-1|mtnW|MasA|DK-MTP-1-P enolase activity				RHEA:18769|MetaCyc:R82-RXN|EC:5.3.2.5	This function is part of the process of methionine salvage.								molecular_function											owl:Class	
GO:0044383	biolink:NamedThing	host chromosome	A structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information, occurring within a host cell.	tmpzr1t_l9r_go_relaxed.owl								jl	2011-12-13T03:58:38Z					cellular_component											owl:Class	
GO:0051991	biolink:NamedThing	UDP-N-acetyl-D-glucosamine:N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine-diphosphoundecaprenol 4-beta-N-acetylglucosaminlytransferase activity	Catalysis of the reaction: N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine-diphosphoundecaprenol + UDP-N-acetyl-D-glucosamine = N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine-diphosphoundecaprenyl-N-acetylglucosamine + UDP.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:NACGLCTRANS-RXN|EC:2.4.1.227|RHEA:31227	Note that EC classifies 'UDP-N-acetyl-D-glucosamine:N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine-diphosphoundecaprenol 4-beta-N-acetylglucosaminlytransferase activity ; GO:0051991' and 'undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase activity ; GO:0050511' under the same EC number, EC:2.4.1.227.		ai	2010-07-06T11:53:19Z					molecular_function											owl:Class	
GO:1904969	biolink:NamedThing	slow muscle cell migration	The orderly movement of a slow muscle cell from one site to another.	tmpzr1t_l9r_go_relaxed.owl	slow-twitch muscle cell migration					The directional migration of a slow muscle cell from one site to another within the embryo.		ymb	2016-02-16T21:20:11Z					biological_process											owl:Class	
GO:0001519	biolink:NamedThing	peptide amidation	The posttranslational conversion of C-terminal glycine-extended peptides to C-terminal alpha-amidated peptides. Occurs to over half of all peptide hormones to give bioactive peptides. This is a two step process catalyzed by a peptidyl-glycine alpha-hydroxylating monooxygenase and a peptidyl-alpha-hydroxyglycine alpha-amidating lyase. In some organisms, this process is catalyzed by two separate enzymes, whereas in higher organisms, one polypeptide catalyzes both reactions.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0031803	biolink:NamedThing	type 6 metabotropic glutamate receptor binding	Binding to a type 6 metabotropic glutamate receptor.	tmpzr1t_l9r_go_relaxed.owl	type 6 metabotropic glutamate receptor ligand													molecular_function											owl:Class	
GO:0044099	biolink:NamedThing	polar tube	A highly specialized structure unique to microsporidia that is required for host cell invasion. In the spore, the polar tube is connected at the anterior end, and then coils around the sporoplasm. Upon appropriate environmental stimulation, the polar tube rapidly discharges out of the spore, pierces a cell membrane and serves as a conduit for sporoplasm passage into the new host cell.	tmpzr1t_l9r_go_relaxed.owl								jl	2009-06-09T03:12:32Z					cellular_component											owl:Class	
GO:0038039	biolink:NamedThing	G protein-coupled receptor heterodimeric complex	A protein complex that contains two G protein-coupled receptors (GPCRs) of different subtypes. Formation of a GPCR heterodimer may alter the functional property of the GPCR.	tmpzr1t_l9r_go_relaxed.owl	G-protein coupled receptor heterodimeric complex|GPCR heterodimer|G-protein coupled receptor heterodimer							bf	2011-11-02T04:44:20Z					cellular_component											owl:Class	
GO:0019668	biolink:NamedThing	anaerobic catabolism of pairs of amino acids	The anaerobic chemical reactions and pathways resulting in the breakdown of amino acids; in these reactions, one amino acid is oxidised (acts as an electron donor) and a different amino acid is reduced (acts as an electron acceptor); oxidation of the electron-donating amino acid yields energy in the form of ATP.	tmpzr1t_l9r_go_relaxed.owl	cofermentation of pairs of amino acids|Stickland reaction													biological_process											owl:Class	
GO:0018719	biolink:NamedThing	6-aminohexanoate transaminase activity	Catalysis of the reaction: 6-aminohexanoate + alpha-ketoglutarate = glutamate + 6-oxohexanoate.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0449|MetaCyc:R562-RXN									molecular_function											owl:Class	
GO:0016691	biolink:NamedThing	chloride peroxidase activity	Catalysis of the reaction: 2 R-H + 2 chloride + hydrogen peroxide = 2 R-Cl + 2 H2O.	tmpzr1t_l9r_go_relaxed.owl	flavin-heme chloroperoxidase activity|flavin-haem chloroperoxidase activity|cofactor-free chloroperoxidase activity|chloroperoxidase activity|vanadium chloroperoxidase activity|heme chloroperoxidase activity|haem chloroperoxidase activity|chloride:hydrogen-peroxide oxidoreductase				EC:1.11.1.10|MetaCyc:CHLORIDE-PEROXIDASE-RXN							GO:0016956|GO:0016955|GO:0016958|GO:0016957		molecular_function											owl:Class	
GO:0017194	biolink:NamedThing	N-terminal peptidyl-isoleucine acetylation	The acetylation of the N-terminal isoleucine of proteins to form the derivative N-acetyl-L-isoleucine. The occurrence of this modification has not been confirmed.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0047									biological_process											owl:Class	
GO:0120136	biolink:NamedThing	dUMP kinase activity	Catalysis of the reaction: ATP + dUMP = ADP + dUDP.	tmpzr1t_l9r_go_relaxed.owl	deoxyuridine monophosphate kinase activity|ATP:dUMP phosphotransferase activity|dUMP-kinase activity				RHEA:30655			krc	2018-03-21T21:16:06Z					molecular_function											owl:Class	
GO:2001142	biolink:NamedThing	nicotinate transport	The directed movement of a nicotinateacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl								tb	2011-10-18T05:09:50Z					biological_process											owl:Class	
GO:0033834	biolink:NamedThing	kaempferol 3-O-galactosyltransferase activity	Catalysis of the reaction: UDP-galactose + kaempferol = UDP + kaempferol 3-O-beta-D-galactoside.	tmpzr1t_l9r_go_relaxed.owl	F3GalTase activity|UDP-galactose:kaempferol 3-O-beta-D-galactosyltransferase activity				EC:2.4.1.234|MetaCyc:2.4.1.234-RXN|RHEA:15709									molecular_function											owl:Class	
GO:0018710	biolink:NamedThing	acetone carboxylase activity	Catalysis of the reaction: acetone + ATP + CO(2) + 2 H(2)O = acetoacetate + AMP + 4 H(+) + 2 phosphate.	tmpzr1t_l9r_go_relaxed.owl	acetone:carbon-dioxide ligase (AMP-forming)				KEGG_REACTION:R05735|MetaCyc:6.4.1.6-RXN|EC:6.4.1.6|RHEA:18385									molecular_function											owl:Class	
GO:0098595	biolink:NamedThing	perivitelline space	The space between the membrane of an oocyte and a surrounding membranous structure (zona pellucida or perivitelline membrane).	tmpzr1t_l9r_go_relaxed.owl								dos	2014-04-08T16:07:31Z					cellular_component											owl:Class	
GO:0035877	biolink:NamedThing	death effector domain binding	Binding to a DED domain (death effector domain) of a protein, a homotypic protein interaction module composed of a bundle of six alpha-helices that is related in structure to the death domain (DD).	tmpzr1t_l9r_go_relaxed.owl	DED binding					For binding to the death domain, consider instead the term 'death domain binding ; GO:0070513'.		bf	2011-05-31T09:40:46Z					molecular_function											owl:Class	
GO:0003374	biolink:NamedThing	dynamin family protein polymerization involved in mitochondrial fission	The process of creating dynamin protein family polymers, compounds composed of a large number of dynamin family monomers around a lipid tube of a dividing mitochondrion. Dynamin polymers form around lipid tubes and contribute to membrane fission.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-12-09T05:39:52Z					biological_process											owl:Class	
GO:0090717	biolink:NamedThing	adaptive immune memory response involving T cells and B cells	An immune response mediated by reactivated memory T cells and B cells and directed against a previously encountered antigen, being quicker and quantitatively better compared with the primary response.	tmpzr1t_l9r_go_relaxed.owl								tb	2016-11-11T12:35:19Z					biological_process											owl:Class	
GO:0033943	biolink:NamedThing	galactan 1,3-beta-galactosidase activity	Catalysis of the hydrolysis of terminal, non-reducing beta-D-galactose residues in (1->3)-beta-D-galactopyranans.	tmpzr1t_l9r_go_relaxed.owl	galactan (1,3)-beta-D-galactosidase activity|galactan (1->3)-beta-D-galactosidase activity				MetaCyc:3.2.1.145-RXN|EC:3.2.1.145									molecular_function											owl:Class	
GO:0004803	biolink:NamedThing	transposase activity	Catalysis of the transposition of transposable elements or transposons. Transposases are involved in recombination required for transposition and are site-specific for the transposon/transposable element.	tmpzr1t_l9r_go_relaxed.owl	P-element encoded transposase activity											GO:0004804		molecular_function											owl:Class	
GO:0044809	biolink:NamedThing	chemokine (C-C motif) ligand 17 production	The appearance of chemokine (C-C motif) ligand 17 (CCL17) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	tmpzr1t_l9r_go_relaxed.owl	CCL17 production|thymus and activation regulated chemokine production|TARC production							jl	2013-09-11T12:21:31Z					biological_process											owl:Class	
GO:0071873	biolink:NamedThing	response to norepinephrine	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a norepinephrine stimulus. Norepinephrine is a catecholamine that has the formula C8H11NO3; it acts as a hormone, and as a neurotransmitter in most of the sympathetic nervous system.	tmpzr1t_l9r_go_relaxed.owl	response to norepinephrine stimulus|response to noradrenaline stimulus					Note that epinephrine and norepinephrine are ligands for the same receptors, and there are multiple adrenergic receptors.		mah	2010-09-13T03:31:53Z					biological_process											owl:Class	
GO:0060816	biolink:NamedThing	random inactivation of X chromosome	Compensating for the two-fold variation in X-chromosome:autosome ratios between sexes by a global inactivation of all, or most of, the genes on either the paternal or maternal X-chromosome in the XX sex.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-08-11T10:47:30Z					biological_process											owl:Class	
GO:0006382	biolink:NamedThing	adenosine to inosine editing	The conversion of an adenosine residue to inosine in an RNA molecule by deamination.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0047968	biolink:NamedThing	glyoxylate dehydrogenase (acylating) activity	Catalysis of the reaction: CoA + glyoxylate + NADP(+) = H(+) + NADPH + oxalyl-CoA.	tmpzr1t_l9r_go_relaxed.owl	glyoxylate:NADP+ oxidoreductase (CoA-oxalylating)				EC:1.2.1.17|MetaCyc:GLYOXYLATE-DEHYDROGENASE-ACYLATING-RXN|KEGG_REACTION:R00468|RHEA:21024									molecular_function											owl:Class	
GO:0047172	biolink:NamedThing	shikimate O-hydroxycinnamoyltransferase activity	Catalysis of the reaction: shikimate + coumaroyl-CoA = 4-coumaroylshikimate + CoA.	tmpzr1t_l9r_go_relaxed.owl	shikimate hydroxycinnamoyltransferase activity|4-coumaroyl-CoA:shikimate O-(hydroxycinnamoyl)transferase activity				EC:2.3.1.133|MetaCyc:2.3.1.133-RXN|RHEA:12124									molecular_function											owl:Class	
GO:0140306	biolink:NamedThing	lipoprotein releasing activity	The activity of recognizing mature outer membrane lipoproteins in the inner membrane and releasing from the inner membrane so that they can be transported across the periplasmic space to their target location, the outer membrane. This function exists in diderm bacteria, mediated by the LolCDE complex.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/17058						pg	2019-03-22T14:25:43Z					molecular_function											owl:Class	
GO:0043562	biolink:NamedThing	cellular response to nitrogen levels	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of inorganic nitrogen.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0019781	biolink:NamedThing	NEDD8 activating enzyme activity	Catalysis of the initiation of the NEDD8 (RUB1) conjugation cascade.	tmpzr1t_l9r_go_relaxed.owl	RUB1 activating enzyme activity	https://github.com/geneontology/go-ontology/issues/22387			EC:6.2.1.64							GO:0019944		molecular_function											owl:Class	
GO:0003721	biolink:NamedThing	telomerase RNA reverse transcriptase activity	Catalysis of the extension of the 3' end of a DNA strand by one deoxynucleotide at a time. Cannot initiate a chain de novo; uses the RNA subunit of the telomerase enzyme complex as its template.	tmpzr1t_l9r_go_relaxed.owl	telomerase, catalyst													molecular_function											owl:Class	
GO:0102164	biolink:NamedThing	2-heptyl-3-hydroxy-4(1H)-quinolone synthase activity	Catalysis of the reaction: 2-heptyl-4-quinolone + NADH + O2 + H+ <=> 2-heptyl-3-hydroxy-4-quinolone + NAD + H2O.	tmpzr1t_l9r_go_relaxed.owl					EC:1.14.13.182|MetaCyc:RXN-11849|RHEA:37871									molecular_function											owl:Class	
GO:2001092	biolink:NamedThing	arabinotriose transport	The directed movement of an arabinotrioseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl								jl	2011-09-21T01:59:36Z					biological_process											owl:Class	
GO:0008823	biolink:NamedThing	cupric reductase activity	Catalysis of the reaction: Cu+ + NAD+ + H+ = Cu2+ + NADH.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:R170-RXN|EC:1.16.1.-									molecular_function											owl:Class	
GO:0072651	biolink:NamedThing	interferon-tau production	The appearance of interferon-tau due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	tmpzr1t_l9r_go_relaxed.owl	IFN-tau production|IFNT production|interferon-tau secretion|IFN-tau secretion					Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.						GO:0072652		biological_process											owl:Class	
GO:0033790	biolink:NamedThing	hydroxymethylfurfural reductase activity	Catalysis of the reaction: 5-hydroxymethylfurfural + NAD(P)H + H+ = 2,5-bis-hydroxymethylfuran + NAD(P)+.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0004588	biolink:NamedThing	orotate phosphoribosyltransferase activity	Catalysis of the reaction: orotidine 5'-phosphate + diphosphate = orotate + 5-phospho-alpha-D-ribose 1-diphosphate.	tmpzr1t_l9r_go_relaxed.owl	orotidine-5'-phosphate pyrophosphorylase activity|orotidine 5'-monophosphate pyrophosphorylase activity|orotidylate phosphoribosyltransferase activity|orotidylate pyrophosphorylase activity|orotidylic acid phosphorylase activity|orotic acid phosphoribosyltransferase activity|orotidylic acid pyrophosphorylase activity|orotidine monophosphate pyrophosphorylase activity|OPRTase activity|orotidylic phosphorylase activity|orotidine-5'-phosphate:diphosphate phospho-alpha-D-ribosyl-transferase activity|orotate phosphoribosyl pyrophosphate transferase activity|orotidine-5'-phosphate diphosphorylase activity|orotidine phosphoribosyltransferase activity|OPRT activity|orotidylic pyrophosphorylase activity				Reactome:R-HSA-73567|EC:2.4.2.10|MetaCyc:OROPRIBTRANS-RXN|RHEA:10380									molecular_function											owl:Class	
GO:0034480	biolink:NamedThing	phosphatidylcholine phospholipase C activity	Catalysis of the reaction: phosphatidylcholine + H2O = 1,2-diacylglycerol + a choline phosphate.	tmpzr1t_l9r_go_relaxed.owl	heat-labile hemolysin|phospholipase C, acting on phosphatidylcholine|Clostridium welchii alpha-toxin activity|Clostridium oedematiens beta- and gamma-toxins activity|lipophosphodiesterase I activity|alpha-toxin|phosphatidylcholine cholinephosphohydrolase activity				RHEA:10604|MetaCyc:PHOSPHOLIPASE-C-RXN|EC:3.1.4.3									molecular_function											owl:Class	
GO:0044606	biolink:NamedThing	phosphocholine hydrolase activity	Catalysis of the reaction: protein-serine-choline phosphate + H2O = protein-serine + choline phosphate.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-05-24T04:46:44Z					molecular_function											owl:Class	
GO:0034609	biolink:NamedThing	spicule insertion	Insertion of the male copulatory spicules into the hermaphrodite. Spicule insertion behavior initiates when the male cloaca contacts the vulva. During most mating encounters, the spicule tips will prod the vulva continuously until they partially penetrate, which then causes the protractors to contract completely so that the spicules extend through the vulva.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0017184	biolink:NamedThing	peptidyl-diphthamide catabolic process	The chemical reactions and pathways resulting in the breakdown of peptidyl-diphthamide, a modified histidine residue.	tmpzr1t_l9r_go_relaxed.owl	peptidyl-diphthamide degradation|peptidyl-diphthamide catabolism|peptidyl-diphthamide breakdown													biological_process											owl:Class	
GO:0006426	biolink:NamedThing	glycyl-tRNA aminoacylation	The process of coupling glycine to glycyl-tRNA, catalyzed by glycyl-tRNA synthetase. The glycyll-tRNA synthetase is a  class-II synthetase. The activated amino acid is transferred to the 3'-OH group of a glycine-accepting tRNA.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0071131	biolink:NamedThing	alphaV-beta3 integrin-laminin alpha-4 complex	A protein complex that consists of an alphaV-beta3 integrin complex bound to laminin alpha-4.	tmpzr1t_l9r_go_relaxed.owl	ITGAV-ITGB3-LAMA4 complex							mah	2009-11-13T02:26:11Z					cellular_component											owl:Class	
GO:1905390	biolink:NamedThing	cellular response to leukotriene B4	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leukotriene B4 stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to LTB4							sl	2016-08-18T16:37:31Z					biological_process											owl:Class	
GO:0090460	biolink:NamedThing	threonine homeostasis	Any process involved in the maintenance of an internal steady state of threonine within an organism or cell.	tmpzr1t_l9r_go_relaxed.owl								tb	2012-09-24T14:22:02Z					biological_process											owl:Class	
GO:0032957	biolink:NamedThing	inositol trisphosphate metabolic process	The chemical reactions and pathways involving myo-inositol phosphate, 1,2,3,4,5,6-cyclohexanehexol, with three phosphate groups attached.	tmpzr1t_l9r_go_relaxed.owl	IP3 metabolism|myo-inositol trisphosphate metabolic process|inositol trisphosphate metabolism|IP3 metabolic process													biological_process											owl:Class	
GO:0016621	biolink:NamedThing	cinnamoyl-CoA reductase activity	Catalysis of the reaction: cinnamaldehyde + CoA + NADP+ = cinnamoyl-CoA + NADPH + H+.	tmpzr1t_l9r_go_relaxed.owl	feruloyl-CoA reductase activity|cinnamoyl-CoA:NADPH reductase activity|ferulyl-CoA reductase activity|cinnamoyl CoA reductase activity|feruloyl coenzyme A reductase activity|cinnamoyl-coenzyme A reductase activity|cinnamaldehyde:NADP+ oxidoreductase (CoA-cinnamoylating)|p-hydroxycinnamoyl coenzyme A reductase activity				MetaCyc:CINNAMOYL-COA-REDUCTASE-RXN|RHEA:10620|EC:1.2.1.44									molecular_function											owl:Class	
GO:0018603	biolink:NamedThing	nitrobenzene 1,2-dioxygenase activity	Catalysis of the reaction: nitrobenzene + NADH + O2 = NAD+ + nitrite + catechol.	tmpzr1t_l9r_go_relaxed.owl					EC:1.14.12.-|UM-BBD_reactionID:r0306									molecular_function											owl:Class	
GO:0070178	biolink:NamedThing	D-serine metabolic process	The chemical reactions and pathways involving D-serine, the D-enantiomer of serine, i.e. (2R)-2-amino-3-hydroxypropanoic acid.	tmpzr1t_l9r_go_relaxed.owl	D-serine metabolism													biological_process											owl:Class	
GO:0034586	biolink:NamedThing	21U-RNA catabolic process	The chemical reactions and pathways resulting in the breakdown of 21U-RNAs, a class of single-stranded RNA molecules of about 21 nucleotides in length characterized by a uridine 5'-monophosphate and a modified 3' end resistant to periodate degradation. 21U-RNAs are derived from distinct, autonomously expressed loci within the genome.	tmpzr1t_l9r_go_relaxed.owl	21U-RNA breakdown|21U-RNA degradation|21U-RNA catabolism													biological_process											owl:Class	
GO:0102176	biolink:NamedThing	cycloeucalenone reductase activity	Catalysis of the reaction: cycloeucalenone + NADPH + H+ <=> cycloeucalenol + NADP.	tmpzr1t_l9r_go_relaxed.owl					EC:1.1.1.270|MetaCyc:RXN-11929									molecular_function											owl:Class	
GO:1990970	biolink:NamedThing	trans-activation response element binding	Binding to a trans-activation response (TAR) element, a hairpin RNA structure located at the 5' end of all HIV-1 transcripts, and which is required for trans-activation of a viral promoter.	tmpzr1t_l9r_go_relaxed.owl	TAR binding							bf	2016-06-21T12:23:00Z					molecular_function											owl:Class	
GO:0008109	biolink:NamedThing	N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity	Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + beta-D-galactosyl-1,4-N-acetyl-D-glucosaminyl-R = UDP + N-acetyl-beta-D-glucosaminyl-1,6-beta-D-galactosyl-1,4-N-acetyl-D-glucosaminyl-R.	tmpzr1t_l9r_go_relaxed.owl	N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase activity|galbeta1->4GlcNAc-R beta1->6 N-acetylglucosaminyltransferase activity|N-acetylglucosaminyltransferase activity|UDP-N-acetyl-D-glucosamine:beta-D-galactosyl-1,4-N-acetyl-D-glucosaminide beta-1,6-N-acetyl-D-glucosaminyltransferase activity|uridine diphosphoacetylglucosamine-acetyllactosaminide beta1->6-acetylglucosaminyltransferase|UDP-GlcNAc:Gal-R, beta-D-6-N-acetylglucosaminyltransferase activity				RHEA:17413|EC:2.4.1.150|MetaCyc:2.4.1.150-RXN									molecular_function											owl:Class	
GO:0043989	biolink:NamedThing	histone H4-S1 phosphorylation	The modification of histone H4 by the addition of an phosphate group to a serine residue at position 1 of the histone.	tmpzr1t_l9r_go_relaxed.owl	histone H4 phosphorylation at S1|histone H4S1 phosphorylation													biological_process											owl:Class	
GO:0014025	biolink:NamedThing	neural keel formation	The formation of a thickened region of the neurectoderm that is roughly triangular in cross section. The neural keel develops from the neural plate and develops into the neural rod. Neural keel formation occurs during primary neurulation in teleosts.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0045095	biolink:NamedThing	keratin filament	A filament composed of acidic and basic keratins (types I and II), typically expressed in epithelial cells. The keratins are the most diverse classes of IF proteins, with a large number of keratin isoforms being expressed. Each type of epithelium always expresses a characteristic combination of type I and type II keratins.	tmpzr1t_l9r_go_relaxed.owl	basic/neutral keratin|acidic keratin													cellular_component											owl:Class	
GO:0022417	biolink:NamedThing	protein maturation by protein folding	The process of assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure that results in the attainment of the full functional capacity of a protein.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0018942	biolink:NamedThing	organometal metabolic process	The chemical reactions and pathways involving organometals, any metal-containing organic compound, especially one in which the metal atom is linked directly to one of more carbon atoms.	tmpzr1t_l9r_go_relaxed.owl	organometal metabolism													biological_process											owl:Class	
GO:0102828	biolink:NamedThing	stachyose galactinol:verbascose galactosyltransferase activity	Catalysis of the reaction: stachyose + alpha-D-galactosyl-(1->3)-1D-myo-inositol <=> verbascose + myo-inositol.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-8284									molecular_function											owl:Class	
GO:0050360	biolink:NamedThing	tryptophan 2'-dioxygenase activity	Catalysis of the reaction: L-tryptophan + O2 = 3-indoleglycolaldehyde + CO2 + NH3.	tmpzr1t_l9r_go_relaxed.owl	L-tryptophan:oxygen 2'-oxidoreductase (side-chain-cleaving)|indolyl-3-alkan alpha-hydroxylase activity|TSO I|tryptophan side chain oxidase II|tryptophan side chain oxidase type I|TSO activity|tryptophan side chain oxidase activity|tryptophan side-chain alpha,beta-oxidase activity|tryptophan side-chain oxidase activity|TSO II|indole-3-alkane alpha-hydroxylase activity				MetaCyc:TRYPTOPHAN-2-DIOXYGENASE-RXN|RHEA:22620|EC:1.13.99.3									molecular_function											owl:Class	
GO:0034626	biolink:NamedThing	fatty acid elongation, polyunsaturated fatty acid	Elongation of a fatty acid chain into which two or more C-C double bonds have been introduced.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1904599	biolink:NamedThing	advanced glycation end-product binding	Binding to advanced glycation end-product.	tmpzr1t_l9r_go_relaxed.owl								krc	2015-08-25T23:39:32Z					molecular_function											owl:Class	
GO:0052881	biolink:NamedThing	4-hydroxyphenylacetate 3-monooxygenase activity	Catalysis of the reaction: (4-hydroxyphenyl)acetate + FADH(2) + O(2) = 3,4-dihydroxyphenylacetate + FAD + H(+) + H(2)O.	tmpzr1t_l9r_go_relaxed.owl	p-hydroxyphenylacetate hydroxylase activity|p-hydroxyphenylacetate 3-hydroxylase activity|p-hydroxyphenylacetate hydroxylase (FAD) activity|4-hydroxyphenylacetic acid-3-hydroxylase activity|p-hydroxyphenylacetate 3-hydroxylase (FAD) activity|4-hydroxyphenylacetate,FADH:oxygen oxidoreductase (3-hydroxylating) activity|4 HPA 3-hydroxylase activity				EC:1.14.14.9|UM-BBD_reactionID:r0301|MetaCyc:RXN-8505|RHEA:30595									molecular_function											owl:Class	
GO:0102896	biolink:NamedThing	colnelenate synthase activity	Catalysis of the reaction: (10E,12Z,15Z)-9-hydroperoxyoctadeca-10,12,15-trienoate <=> colnelenate + H2O.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-8498|RHEA:28178									molecular_function											owl:Class	
GO:0097266	biolink:NamedThing	phenylacetyl-CoA 1,2-epoxidase activity	Catalysis of the reaction: phenylacetyl-CoA + H(+) + NADPH + O2 = 2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA + H2O + NADP(+).	tmpzr1t_l9r_go_relaxed.owl	phenylacetyl-CoA epoxidase activity|ring 1,2-phenylacetyl-CoA epoxidase activity|phenylacetyl-CoA monooxygenase activity				RHEA:32171|EC:1.14.13.149|KEGG_REACTION:R09838			pr	2012-03-13T09:22:47Z					molecular_function											owl:Class	
GO:0015716	biolink:NamedThing	organic phosphonate transport	The directed movement of phosphonates into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A phosphonate is any salt, anion, or ester of phosphonic acid (HPO(OH)2).	tmpzr1t_l9r_go_relaxed.owl	alkylphosphonate transport	https://github.com/geneontology/go-ontology/issues/17164										GO:0042916		biological_process											owl:Class	
GO:0046517	biolink:NamedThing	octamethylcyclotetrasiloxane catabolic process	The chemical reactions and pathways resulting in the breakdown of octamethylcyclotetrasiloxane, a cyclic silicone-oxygen ring compound with two methyl groups attached to each silicone atom.	tmpzr1t_l9r_go_relaxed.owl	octamethylcyclotetrasiloxane catabolism|octamethylcyclotetrasiloxane degradation|octamethylcyclotetrasiloxane breakdown													biological_process											owl:Class	
GO:0047861	biolink:NamedThing	diiodotyrosine transaminase activity	Catalysis of the reaction: 2-oxoglutarate + 3,5-diiodo-L-tyrosine = 3-(3,5-diiodo-4-hydroxyphenyl)pyruvate + L-glutamate.	tmpzr1t_l9r_go_relaxed.owl	3,5-diiodo-L-tyrosine:2-oxoglutarate aminotransferase activity|diiodotyrosine aminotransferase activity|halogenated tyrosine transaminase activity|halogenated tyrosine aminotransferase activity				MetaCyc:DIIODOTYROSINE-AMINOTRANSFERASE-RXN|RHEA:19781|KEGG_REACTION:R03207|EC:2.6.1.24									molecular_function											owl:Class	
GO:1990294	biolink:NamedThing	peptidyl-threonine trans-autophosphorylation	The phosphorylation of a peptidyl-threonine to form peptidyl-O-phospho-L-threonine on an identical protein. For example, phosphorylation by the other kinase within a homodimer.	tmpzr1t_l9r_go_relaxed.owl								al	2014-02-05T12:42:46Z					biological_process											owl:Class	
GO:1901356	biolink:NamedThing	beta-D-galactofuranose metabolic process	The chemical reactions and pathways involving beta-D-galactofuranose.	tmpzr1t_l9r_go_relaxed.owl	beta-D-galactofuranose metabolism							di	2012-09-13T22:18:20Z					biological_process											owl:Class	
GO:0097121	biolink:NamedThing	cyclin A1-CDK1 complex	A protein complex consisting of cyclin A1 and cyclin-dependent kinase 1 (CDK1). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner.	tmpzr1t_l9r_go_relaxed.owl								pr	2011-08-01T01:41:25Z					cellular_component											owl:Class	
GO:0050287	biolink:NamedThing	sorbose 5-dehydrogenase (NADP+) activity	Catalysis of the reaction: L-sorbose + NADP(+) = 5-dehydro-D-fructose + H(+) + NADPH.	tmpzr1t_l9r_go_relaxed.owl	L-sorbose:NADP+ 5-oxidoreductase activity|5-keto-D-fructose reductase activity|5-ketofructose reductase activity|sorbose (nicotinamide adenine dinucleotide phosphate) dehydrogenase activity|reduced nicotinamide adenine dinucleotide phosphate-linked reductase activity				RHEA:15001|EC:1.1.1.123|KEGG_REACTION:R01694|MetaCyc:SORBOSE-5-DEHYDROGENASE-NADP+-RXN									molecular_function											owl:Class	
GO:0018424	biolink:NamedThing	peptidyl-glutamic acid poly-ADP-ribosylation	This modification produces peptidyl-glutamic acid poly-ADP-ribose found in a number of nuclear proteins under certain conditions including the repair of single strand DNA breaks. The activated form of the generating enzyme poly(ADP-ribose) polymerase is itself modified in this way.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0295									biological_process											owl:Class	
GO:0019373	biolink:NamedThing	epoxygenase P450 pathway	The chemical reactions and pathways by which arachidonic acid is converted to other compounds including epoxyeicosatrienoic acids and dihydroxyeicosatrienoic acids.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0008511	biolink:NamedThing	sodium:potassium:chloride symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Na+(out) + K+(out) + Cl-(out) = Na+(in) + K+(in) + Cl-(in).	tmpzr1t_l9r_go_relaxed.owl	sodium/potassium/chloride symporter activity				Reactome:R-HSA-426086|Reactome:R-HSA-5623588									molecular_function											owl:Class	
GO:0072732	biolink:NamedThing	cellular response to calcium ion starvation	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of calcium ions.	tmpzr1t_l9r_go_relaxed.owl	cellular response to calcium starvation							mah	2012-07-06T02:42:26Z					biological_process											owl:Class	
GO:0047653	biolink:NamedThing	allantoin racemase activity	Catalysis of the reaction: (S)-(+)-allantoin = (R)-(-)-allantoin.	tmpzr1t_l9r_go_relaxed.owl					EC:5.1.99.3|RHEA:10804|MetaCyc:ALLANTOIN-RACEMASE-RXN|KEGG_REACTION:R03925									molecular_function											owl:Class	
GO:0019712	biolink:NamedThing	peptidyl-L-glutamic acid 5-methyl ester biosynthetic process from glutamic acid	The methyl esterification of peptidyl-glutamic acid.	tmpzr1t_l9r_go_relaxed.owl	peptidyl-L-glutamic acid 5-methyl ester anabolism from glutamic acid|peptidyl-L-glutamic acid 5-methyl ester synthesis from glutamic acid|peptidyl-L-glutamic acid 5-methyl ester formation from glutamic acid				RESID:AA0072									biological_process											owl:Class	
GO:0047265	biolink:NamedThing	poly(glycerol-phosphate) alpha-glucosyltransferase activity	Catalysis of the reaction: poly(glycerol phosphate) + UDP-D-glucose = alpha-D-glucosylpoly(glycerol phosphate) + UDP.	tmpzr1t_l9r_go_relaxed.owl	UDP-glucose:poly(glycerol-phosphate) alpha-D-glucosyltransferase activity|UDPglucose:poly(glycerol-phosphate) alpha-D-glucosyltransferase activity|UDP glucose-poly(glycerol-phosphate) alpha-glucosyltransferase activity|uridine diphosphoglucose-poly(glycerol-phosphate) alpha-glucosyltransferase activity				EC:2.4.1.52|MetaCyc:2.4.1.52-RXN|RHEA:15845									molecular_function											owl:Class	
GO:0047234	biolink:NamedThing	raffinose-raffinose alpha-galactotransferase activity	Catalysis of the reaction: 2 raffinose = sucrose + 1F-alpha-D-galactosylraffinose.	tmpzr1t_l9r_go_relaxed.owl	raffinose (raffinose donor) galactosyltransferase activity|raffinose-raffinose a-galactosyltransferase activity|raffinose:raffinose alpha-D-galactosyltransferase activity|raffinose:raffinose alpha-galactosyltransferase activity|raffinose-raffinose alpha-galactosyltransferase activity				MetaCyc:2.4.1.166-RXN|EC:2.4.1.166|RHEA:14125									molecular_function											owl:Class	
GO:0008874	biolink:NamedThing	gluconate 5-dehydrogenase activity	Catalysis of the reaction: D-gluconate + NADP+ = 5-dehydro-D-gluconate + NADPH + H+.	tmpzr1t_l9r_go_relaxed.owl	5-keto-D-gluconate reductase|5-ketogluconate reductase activity|D-gluconate:NAD(P)+ 5-oxidoreductase|5-ketogluconate 5-reductase activity|5-keto-D-gluconate 5-reductase activity				MetaCyc:GLUCONATE-5-DEHYDROGENASE-RXN|EC:1.1.1.69									molecular_function											owl:Class	
GO:0018477	biolink:NamedThing	benzaldehyde dehydrogenase (NADP+) activity	Catalysis of the reaction: benzaldehyde + NADP+ + H2O = benzoate + NADPH + H+.	tmpzr1t_l9r_go_relaxed.owl	benzaldehyde:NADP+ oxidoreductase|NADP-linked benzaldehyde dehydrogenase				RHEA:21660|EC:1.2.1.7|MetaCyc:BENZALDEHYDE-DEHYDROGENASE-NADP+-RXN|UM-BBD_enzymeID:e0079									molecular_function											owl:Class	
GO:0003726	biolink:NamedThing	double-stranded RNA adenosine deaminase activity	Catalysis of the reaction: adenosine + H2O = inosine + NH3, in a double-stranded RNA molecule.	tmpzr1t_l9r_go_relaxed.owl	double-stranded RNA specific editase activity				Reactome:R-HSA-77615|Reactome:R-HSA-77614							GO:0003971		molecular_function											owl:Class	
GO:0071176	biolink:NamedThing	MAML2-RBP-Jkappa-ICN2 complex	A protein complex that consists of the intracellular domain of Notch2 (ICN2), the DNA-binding transcription factor RBP-Jkappa, and the transcriptional coactivator Mastermind-like-2 (MAML2); the complex is involved in transcriptional activation in response to Notch-mediated signaling.	tmpzr1t_l9r_go_relaxed.owl	MAML2-RBP-Jkappa-Notch2 complex							mah	2009-11-23T02:42:24Z					cellular_component											owl:Class	
GO:0019549	biolink:NamedThing	glutamate catabolic process to succinate via succinate semialdehyde	The chemical reactions and pathways resulting in the breakdown of glutamate into succinate, that includes the conversion of 4-aminobutyrate to succinate semialdehyde by the pyruvate-dependent gamma aminobutyrate (GABA) transaminase.	tmpzr1t_l9r_go_relaxed.owl	glutamate degradation to succinate|glutamate catabolic process to succinate via pyruvate-dependent GABA-transaminase activity|glutamate breakdown to succinate				MetaCyc:PWY-4321	While mammals only have 2-oxoglutarate-dependent GABA-transaminase, both 2-oxoglutarate-dependent and pyruvate-dependent GABA-transaminase activities have been detected in plants.								biological_process											owl:Class	
GO:0089717	biolink:NamedThing	spanning component of membrane	The component of a membrane consisting of gene products and protein complexes that have some part that spans both leaflets of the membrane.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0070558	biolink:NamedThing	alphaM-beta2 integrin-CD63 complex	A protein complex that consists of an alphaM-beta2 integrin complex bound to membrane protein CD63, a member of the tetraspan family.	tmpzr1t_l9r_go_relaxed.owl	ITGAM-ITGB2-CD63 complex													cellular_component											owl:Class	
GO:0004098	biolink:NamedThing	cerebroside-sulfatase activity	Catalysis of the reaction: a cerebroside 3-sulfate + H2O = a cerebroside + sulfate.	tmpzr1t_l9r_go_relaxed.owl	cerebroside-sulphatase activity|arylsulfatase A activity|cerebroside-3-sulfate 3-sulfohydrolase activity|cerebroside sulfate sulfatase activity				RHEA:21300|EC:3.1.6.8|Reactome:R-HSA-1606807|MetaCyc:CEREBROSIDE-SULFATASE-RXN									molecular_function											owl:Class	
GO:0070380	biolink:NamedThing	high mobility group box 1 receptor activity	Combining with high mobility group box 1 (HMBGB1) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	HMGB1 receptor activity													molecular_function											owl:Class	
GO:0015109	biolink:NamedThing	chromate transmembrane transporter activity	Enables the transfer of chromate from one side of a membrane to the other. Chromate is the anion of chromic acid, H2CrO4 (aq) or CrO3.	tmpzr1t_l9r_go_relaxed.owl					RHEA:32819									molecular_function											owl:Class	
GO:0046780	biolink:NamedThing	suppression by virus of host mRNA splicing	Any viral process that inhibits the splicing of host mRNA, thus reducing host protein production.	tmpzr1t_l9r_go_relaxed.owl	negative regulation by virus of host mRNA splicing|viral inhibition of host mRNA splicing|suppression by virus of host splicing factor activity|viral dispersion of host splicing factors											GO:0046781		biological_process											owl:Class	
GO:0102636	biolink:NamedThing	3-benzyl-3,6 -bis(glutathione)- 6-(hydroxymethyl)-diketopiperazine gamma-glutamylcyclotransferase activity	Catalysis of the reaction: 3-benzyl-3,6 -bis(glutathione)- 6-(hydroxymethyl)-diketopiperazine <=> 3-benzyl-3,6 -bis(cysteinylglycine)- 6-(hydroxymethyl)-diketopiperazine + 2 5-oxo-L-prolinate.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-15681									molecular_function											owl:Class	
GO:0102719	biolink:NamedThing	S-adenosyl-L-methionine:eugenol-O-methyltransferase activity	Catalysis of the reaction: eugenol + S-adenosyl-L-methionine  = H+ + O-methyleugenol + S-adenosyl-L-homocysteine.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-6741|EC:2.1.1.146									molecular_function											owl:Class	
GO:0005955	biolink:NamedThing	calcineurin complex	A heterodimeric calcium ion and calmodulin dependent protein phosphatase composed of catalytic and regulatory subunits; the regulatory subunit is very similar in sequence to calmodulin.	tmpzr1t_l9r_go_relaxed.owl	protein phosphatase type 2B complex|calcium-dependent protein serine/threonine phosphatase complex													cellular_component											owl:Class	
GO:0033296	biolink:NamedThing	rhamnose binding	Binding to the D- or L-enantiomer of rhamnose.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0019382	biolink:NamedThing	carbon tetrachloride catabolic process	The chemical reactions and pathways resulting in the breakdown of carbon tetrachloride, a toxic, carcinogenic compound which is used as a general solvent in industrial degreasing operations. It is also used as grain fumigant and a chemical intermediate in the production of refrigerants.	tmpzr1t_l9r_go_relaxed.owl	carbon tetrachloride breakdown|carbon tetrachloride degradation|carbon tetrachloride catabolism													biological_process											owl:Class	
GO:0046480	biolink:NamedThing	galactolipid galactosyltransferase activity	Catalysis of the reaction: 2 mono-beta-D-galactosyldiacylglycerol = alpha-D-galactosyl-beta-D-galactosyldiacylglycerol + 1,2-diacylglycerol.	tmpzr1t_l9r_go_relaxed.owl	galactolipid-galactolipid galactosyltransferase activity|digalactosyldiacylglycerol synthase activity|interlipid galactosyltransferase activity|DGDG synthase activity|galactolipid:galactolipid galactosyltransferase activity|3-(beta-D-galactosyl)-1,2-diacyl-sn-glycerol:mono-3-(beta-D-galactosyl)-1,2-diacyl-sn-glycerol beta-D-galactosyltransferase activity|GGGT activity				RHEA:15921|EC:2.4.1.184|MetaCyc:RXN-1226									molecular_function											owl:Class	
GO:0106059	biolink:NamedThing	tRNA (cytidine 56-2'-O)-methyltransferase	Catalysis of the reaction: S-adenosyl-L-methionine + cytidine56 in tRNA= S-adenosyl-L-homocysteine + 2'-O-methylcytidine56 in tRNA.	tmpzr1t_l9r_go_relaxed.owl								hjd	2017-10-05T19:02:22Z					molecular_function											owl:Class	
GO:0080019	biolink:NamedThing	fatty-acyl-CoA reductase (alcohol-forming) activity	Catalysis of the reaction: a very long chain fatty acyl-CoA + NADPH + H+ = a very long chain primary alcohol + NADP+ + CoA.	tmpzr1t_l9r_go_relaxed.owl	fatty acyl CoA reductase (alcohol-forming) activity|fatty acyl-CoA reductase (alcohol-forming) activity													molecular_function											owl:Class	
GO:0047580	biolink:NamedThing	4-hydroxyproline epimerase activity	Catalysis of the reaction: trans-4-hydroxy-L-proline = cis-4-hydroxy-D-proline.	tmpzr1t_l9r_go_relaxed.owl	L-hydroxyproline epimerase activity|hydroxyproline 2-epimerase activity|hydroxyproline epimerase activity|4-hydroxyproline 2-epimerase activity				KEGG_REACTION:R03296|RHEA:21152|MetaCyc:4-HYDROXYPROLINE-EPIMERASE-RXN|EC:5.1.1.8									molecular_function											owl:Class	
GO:0050201	biolink:NamedThing	fucokinase activity	Catalysis of the reaction: L-fucose + ATP = beta-L-fucose 1-phosphate + ADP + 2 H(+).	tmpzr1t_l9r_go_relaxed.owl	ATP:beta-L-fucose 1-phosphotransferase activity|L-fucose kinase activity|L-fucokinase activity|fucose kinase activity|ATP:6-deoxy-L-galactose 1-phosphotransferase activity|fucokinase (phosphorylating) activity				EC:2.7.1.52|RHEA:13241|MetaCyc:FUCOKINASE-RXN|KEGG_REACTION:R03161|Reactome:R-HSA-6787540									molecular_function											owl:Class	
GO:0016617	biolink:NamedThing	4-oxoproline reductase activity	Catalysis of the reaction: 4-hydroxy-L-proline + NAD+ = 4-oxoproline + NADH + H+.	tmpzr1t_l9r_go_relaxed.owl	hydroxy-L-proline oxidase activity|4-hydroxy-L-proline:NAD+ oxidoreductase activity|hydroxyproline oxidase activity				EC:1.1.1.104|MetaCyc:4-OXOPROLINE-REDUCTASE-RXN|RHEA:13601									molecular_function											owl:Class	
GO:0102926	biolink:NamedThing	solanidine glucosyltransferase activity	Catalysis of the reaction: UDP-alpha-D-glucose + solanidine = H+ + gamma-chaconine + UDP.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-8882									molecular_function											owl:Class	
GO:1904802	biolink:NamedThing	RITS complex assembly	The aggregation, arrangement and bonding together of a set of components to form a RITS complex.	tmpzr1t_l9r_go_relaxed.owl	RITS complex formation							mah	2015-11-09T16:17:54Z					biological_process											owl:Class	
GO:0005862	biolink:NamedThing	muscle thin filament tropomyosin	A form of the tropomyosin dimer found associated with actin and the troponin complex in muscle thin filaments.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0018717	biolink:NamedThing	9-phenanthrol glycosyltransferase activity	Catalysis of the reaction: 9-phenanthrol + glucose = 9-phenanthryl-beta-D-glucopyranoside + H2O.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0511									molecular_function											owl:Class	
GO:2001050	biolink:NamedThing	negative regulation of tendon cell differentiation	Any process that stops, prevents or reduces the frequency, rate or extent of tendon cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of muscle attachment cell differentiation|negative regulation of tenocyte differentiation							yaf	2011-09-01T09:20:38Z					biological_process											owl:Class	
GO:0140445	biolink:NamedThing	chromosome, telomeric repeat region	A complex of DNA and protein that seals the end of a chromosome. The telomeric repeat DNA consists of simple tandemly repeated sequences specific for each species. Typically one strand is G-rich and the other C-rich. The G-rich strand forms a 3'-terminal overhang, the length of which varies with species. The single strand overhang is bound by a variety of proteins, including telomere capping proteins that bind to the single-stranded DNA and seal the telomeric loop.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/19086						pg	2020-03-27T13:29:16Z					cellular_component											owl:Class	
GO:0060647	biolink:NamedThing	mesenchymal cell condensation involved in mammary fat development	The cell adhesion process in which mammary mesenchyme cells adhere to one another in the initial stages of the formation of mammary fat development.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-05-29T08:33:29Z					biological_process											owl:Class	
GO:0051994	biolink:NamedThing	P-methyltransferase activity	Catalysis of the transfer of a methyl group to the phosphorus atom of an acceptor molecule.	tmpzr1t_l9r_go_relaxed.owl					EC:2.1.1.-			ai	2010-07-16T04:39:34Z					molecular_function											owl:Class	
GO:0014045	biolink:NamedThing	establishment of endothelial blood-brain barrier	Establishment of the endothelial barrier between the blood and the brain. The endothelial cells in the brain capillaries are packed tightly together preventing the passage of most molecules from the blood into the brain. Only lipid soluble molecules or those that are actively transported can pass through the blood-brain barrier.	tmpzr1t_l9r_go_relaxed.owl	establishment of endothelial BBB|establishment of endothelial blood/brain barrier													biological_process											owl:Class	
GO:0150111	biolink:NamedThing	regulation of transepithelial transport	Any process that modulates the frequency, rate or extent of transepithelial transport.	tmpzr1t_l9r_go_relaxed.owl								bc	2019-09-15T07:16:49Z					biological_process											owl:Class	
GO:0004504	biolink:NamedThing	peptidylglycine monooxygenase activity	Catalysis of the reaction: peptidyl-glycine + ascorbate + O2 = peptidyl(2-hydroxyglycine) + dehydroascorbate + H2O.	tmpzr1t_l9r_go_relaxed.owl	PAM-A|PAM-B|peptidylglycine alpha-hydroxylase activity|peptidylglycine 2-hydroxylase activity|synthase, peptide alpha-amide|peptidylglycine alpha-amidating monooxygenase activity|peptide alpha-amidating enzyme|peptide-alpha-amide synthetase activity|peptide alpha-amide synthase activity|peptidylglycine,ascorbate:oxygen oxidoreductase (2-hydroxylating)|peptidyl alpha-amidating enzyme activity|PAM activity				RHEA:21452|MetaCyc:PEPTIDYLGLYCINE-MONOOXYGENASE-RXN|EC:1.14.17.3									molecular_function											owl:Class	
GO:0140655	biolink:NamedThing	mitochondrial proliferation	The multiplication of mitochondria, resulting in the expansion of the number of mitochondria within a cell.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/21537						pg	2021-06-04T10:23:02Z					biological_process											owl:Class	
GO:0047625	biolink:NamedThing	adenosylmethionine cyclotransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine(1+) = S-methyl-5'-thioadenosine + homoserine lactone.	tmpzr1t_l9r_go_relaxed.owl	S-adenosyl-L-methionine alkyltransferase (cyclizing)|adenosyl methionine cyclotransferase activity|adenosylmethioninase activity				EC:2.5.1.4|RHEA:21932|MetaCyc:ADENOSYLMETHIONINE-CYCLOTRANSFERASE-RXN|KEGG_REACTION:R00180									molecular_function											owl:Class	
GO:1990663	biolink:NamedThing	dihydroorotate dehydrogenase (fumarate) activity	Catalysis of the reaction: (S)-dihydroorotate + fumarate = orotate + succinate.	tmpzr1t_l9r_go_relaxed.owl					EC:1.3.98.1|RHEA:30059			al	2015-02-26T15:47:30Z					molecular_function											owl:Class	
GO:0003925	biolink:NamedThing	G protein activity	A molecular function regulator that cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate cellular processes. Intrinsic GTPase activity returns the G protein to its GDP-bound state. The return to the GDP-bound state can be accelerated by the action of a GTPase-activating protein (GAP).	tmpzr1t_l9r_go_relaxed.owl	large G-protein GTPase activity|large G-protein activity|small monomeric GTPase activity|small monomeric G protein activity|heterotrimeric G-protein GTPase activity|signaling G protein activity	https://github.com/geneontology/go-ontology/issues/19082			EC:3.6.5.2|EC:3.6.5.1|MetaCyc:3.6.1.47-RXN|MetaCyc:3.6.1.46-RXN							GO:0003927		molecular_function											owl:Class	
GO:0060792	biolink:NamedThing	sweat gland development	The progression of the sweat gland over time, from its formation to the mature structure. Sweat glands secrete an aqueous solution that is used in thermoregulation.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-08-04T12:35:12Z					biological_process											owl:Class	
GO:0047261	biolink:NamedThing	steroid N-acetylglucosaminyltransferase activity	Catalysis of the reaction: estradiol-17alpha 3-D-glucuronoside + UDP-N-acetyl-alpha-D-glucosamine = 17alpha-(N-acetyl-D-glucosaminyl)-estradiol 3-D-glucuronoside + H(+) + UDP.	tmpzr1t_l9r_go_relaxed.owl	UDP-N-acetyl-D-glucosamine:estradiol-17alpha-3-D-glucuronoside 17alpha-N-acetylglucosaminyltransferase activity|steroid acetylglucosaminyltransferase activity|hydroxy steroid acetylglucosaminyltransferase activity|uridine diphosphoacetylglucosamine-steroid acetylglucosaminyltransferase activity				RHEA:14153|MetaCyc:2.4.1.39-RXN|EC:2.4.1.39|KEGG_REACTION:R04451									molecular_function											owl:Class	
GO:0036236	biolink:NamedThing	acyl glucuronidation	The modification of an substrate by the conjugation of glucuronic acid to form an acyl-glucuronide (also called an acyl-glucuronoside).	tmpzr1t_l9r_go_relaxed.owl								bf	2012-05-18T04:26:25Z					biological_process											owl:Class	
GO:0044334	biolink:NamedThing	canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition	The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes involved in the positive regulation of epithelial cell to mesenchymal cell transition.	tmpzr1t_l9r_go_relaxed.owl	canonical Wnt receptor signaling pathway involved in positive regulation of epithelial to mesenchymal transition|canonical Wnt receptor signalling pathway involved in positive regulation of epithelial to mesenchymal transition|canonical Wnt-activated signaling pathway involved in positive regulation of epithelial to mesenchymal transition							jl	2010-08-20T02:35:17Z					biological_process											owl:Class	
GO:0031174	biolink:NamedThing	lifelong otolith mineralization	The formation and growth of otoliths throughout the life of the organism. Otoliths are the large extracellular ear-stones of the fish inner ear, produced by precipitation of specific crystal forms of calcium carbonate on organic matrices. The otolith enlarges throughout the life of the fish, as layers of calcium carbonate are added.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0015625	biolink:NamedThing	ABC-type ferric hydroxamate transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + ferric-hydroxamate(out) = ADP + phosphate + ferric-hydroxamate(in).	tmpzr1t_l9r_go_relaxed.owl	ATPase-coupled iron-chelate transporter activity|ATPase-coupled ferric-hydroxamate transmembrane transporter activity|ATP-dependent iron-chelate transporter activity|iron-chelate-transporting ATPase activity|ATP-dependent ferric-hydroxamate transmembrane transporter activity|ferric-hydroxamate-transporting ATPase activity|ferric-hydroxamate ABC transporter|ferric-hydroxamate porter activity|ferric-hydroxamate transmembrane transporter activity	https://github.com/geneontology/go-ontology/issues/17164			EC:7.2.2.16|MetaCyc:ABC-11-RXN|MetaCyc:ABC-9-RXN|MetaCyc:3.6.3.34-RXN							GO:0015622|GO:0015623|GO:0015409|GO:0102026		molecular_function											owl:Class	
GO:0048028	biolink:NamedThing	galacturonan binding	Binding to a simple or complex galacturonan. Galacturonan is any glycan composed solely of galacturonic acid residues, a specific type of glycuronan, and a constituent of some pectins.	tmpzr1t_l9r_go_relaxed.owl	polygalacturonide binding													molecular_function											owl:Class	
GO:0034965	biolink:NamedThing	intronic box C/D RNA processing	Any process involved in the conversion of a primary box C/D type small nucleolar RNA (snoRNA) transcript that resides within, and is processed from, the intron of a pre-mRNA into a mature box C/D snoRNA.	tmpzr1t_l9r_go_relaxed.owl	intronic box C/D sRNA processing|intronic box C/D snoRNA processing													biological_process											owl:Class	
GO:1990530	biolink:NamedThing	Cdc50p-Drs2p complex	A protein complex that functions as a phospholipid-translocating P-Type ATPase. In budding yeast, this complex consists of Cdc50p and Drs2p proteins, and is involved in the trafficking of transport vesicles between the late Golgi and the early endosome.	tmpzr1t_l9r_go_relaxed.owl								rb	2014-11-06T01:29:31Z					cellular_component											owl:Class	
GO:1990531	biolink:NamedThing	phospholipid-translocating ATPase complex	A protein complex that functions as a phospholipid-translocating P-Type ATPase.	tmpzr1t_l9r_go_relaxed.owl	APLT complex|P4-ATPase complex|Dnf1-Lem3 complex|CDC50-DRS2 complex|DRS2-CDC50 complex|Lem3p-Dnf1p complex|Lem3-Dnf1 complex|Dnf2-Lem3 complex|DNF3-CRF1 complex|CRF1-DNF3 complex|phospholipid flippase complex|aminophospholipid translocase complex							rb	2014-11-06T22:33:25Z					cellular_component											owl:Class	
GO:0033728	biolink:NamedThing	divinyl chlorophyllide a 8-vinyl-reductase activity	Catalysis of the reaction: chlorophyllide a + NADP+ = divinyl chlorophyllide a + NADPH + H+.	tmpzr1t_l9r_go_relaxed.owl	chlorophyllide-a:NADP+ oxidoreductase activity|[4-vinyl]chlorophyllide a reductase activity|4VCR				MetaCyc:RXN-5286|EC:1.3.1.75|RHEA:14449									molecular_function											owl:Class	
GO:0004853	biolink:NamedThing	uroporphyrinogen decarboxylase activity	Catalysis of the reaction: uroporphyrinogen-III = coproporphyrinogen + 4 CO2.	tmpzr1t_l9r_go_relaxed.owl	uroporphyrinogen-III carboxy-lyase (coproporphyrinogen-III-forming)|porphyrinogen decarboxylase activity|porphyrinogen carboxy-lyase activity|uroporphyrinogen-III carboxy-lyase activity|uroporphyrinogen III decarboxylase activity				Reactome:R-HSA-189425|RHEA:19865|Reactome:R-HSA-190182|MetaCyc:UROGENDECARBOX-RXN|EC:4.1.1.37									molecular_function											owl:Class	
GO:0050195	biolink:NamedThing	phosphoribokinase activity	Catalysis of the reaction: D-ribose 5-phosphate + ATP = D-ribose 1,5-diphosphate + ADP + 2 H(+).	tmpzr1t_l9r_go_relaxed.owl	phosphoribokinase (phosphorylating)|ATP:D-ribose-5-phosphate 1-phosphotransferase activity				KEGG_REACTION:R01050|EC:2.7.1.18|MetaCyc:PHOSPHORIBOKINASE-RXN|RHEA:21216									molecular_function											owl:Class	
GO:0102308	biolink:NamedThing	erythromycin D 3''-o-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine  + erythromycin D <=> S-adenosyl-L-homocysteine  + erythromycin B + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-12924|EC:2.1.1.254|RHEA:32651									molecular_function											owl:Class	
GO:0005964	biolink:NamedThing	phosphorylase kinase complex	An enzyme complex that catalyzes the phosphorylation of phosphorylase b to form phosphorylase a.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0004795	biolink:NamedThing	threonine synthase activity	Catalysis of the reaction: O-phospho-L-homoserine + H2O = L-threonine + phosphate.	tmpzr1t_l9r_go_relaxed.owl	O-phospho-L-homoserine phospho-lyase (adding water; L-threonine-forming)|threonine synthetase activity|O-phospho-L-homoserine phospho-lyase (adding water)				MetaCyc:THRESYN-RXN|EC:4.2.3.1|RHEA:10840									molecular_function											owl:Class	
GO:0000140	biolink:NamedThing	acylglycerone-phosphate reductase activity	Catalysis of the reaction: 1-palmitoylglycerol-3-phosphate + NADP+ = palmitoylglycerone phosphate + NADPH + H(+).	tmpzr1t_l9r_go_relaxed.owl	1-acyldihydroxyacetone-phosphate reductase activity|acyldihydroxyacetone phosphate reductase activity|1-palmitoylglycerol-3-phosphate:NADP+ oxidoreductase activity|palmitoyl dihydroxyacetone phosphate reductase activity|palmitoyl-dihydroxyacetone-phosphate reductase activity|palmitoyldihydroxyacetone-phosphate reductase activity				MetaCyc:ACYLGLYCERONE-PHOSPHATE-REDUCTASE-RXN|RHEA:17341|Reactome:R-HSA-75883|EC:1.1.1.101									molecular_function											owl:Class	
GO:0062157	biolink:NamedThing	mitochondrial ATP-gated potassium channel complex	A protein-containing complex that is capable of the ATP-dependent diffusion of a potassium ion across the mitochondrial inner membrane.	tmpzr1t_l9r_go_relaxed.owl								dph	2019-09-20T16:17:05Z					cellular_component											owl:Class	
GO:0046359	biolink:NamedThing	butyrate catabolic process	The chemical reactions and pathways resulting in the breakdown of butyrate, the anion of butyric acid.	tmpzr1t_l9r_go_relaxed.owl	butyrate breakdown|butyrate catabolism|butyrate degradation|butanoic acid degradation|butanoic acid catabolism|butanoic acid breakdown|butanoic acid catabolic process											GO:0043440		biological_process											owl:Class	
GO:0055048	biolink:NamedThing	anastral spindle assembly	The aggregation, arrangement and bonding together of a set of components to form the spindle, the array of microtubules and associated molecules that serves to move duplicated chromosomes apart, in the absence of centrosomes. Formation is initiated by the nucleation of microtubules (MTs) in the vicinity of condensed chromatin. MTs then attach to and congress around the chromatin due to activity of microtubule motors. A bipolar spindle is formed by focusing of the terminal ends of the MT array into spindle poles by molecular motors and cross-linking proteins.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0034662	biolink:NamedThing	CFTR-NHERF-ezrin complex	A protein complex that contains ezrin, Na+/H+ exchanger regulatory factor (NHERF, also called EBP50), and two copies of the cystic fibrosis transmembrane conductance regulator (CFTR). The CFTR molecules interact with NHERF via their cytoplasmic tail domains; the complex is thought to link the CFTR channel to the actin cytoskeleton and contribute to the regulation of channel activity.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0061744	biolink:NamedThing	motor behavior	The specific neuromuscular movement of a single organism in response to external or internal stimuli.	tmpzr1t_l9r_go_relaxed.owl								dph	2015-11-09T12:43:11Z					biological_process											owl:Class	
GO:0140091	biolink:NamedThing	mBAF complex	A muscle cell-specific SWI/SNF-type complex that contains eight to fourteen proteins, including both conserved (core) and nonconserved components; contains the ATPase product of either the SMARCA4/BAF190A/BRG1 gene, the mammalian ortholog of the yeast SNF2 gene, or the SMARCA2/BAF190B/BRM gene, the mammalian ortholog of the Drosophila brm (brahma) gene, or an ortholog of either of these genes, and the muscle-specific product of the DPF3/BAF45C gene or an ortholog thereof.	tmpzr1t_l9r_go_relaxed.owl	muscle-specific SWI/SNF complex|muscle-type SWI/SNF complex|muscle-specific BAF complex|muscle-type BAF complex							pg	2017-09-05T09:20:45Z					cellular_component											owl:Class	
GO:0019926	biolink:NamedThing	peptidyl-tryptophan oxidation to tryptophyl quinone	The oxidation of peptidyl-tryptophan to form tryptophan-6,7-dione, otherwise known as tryptophyl quinone, which is further modified by cross-linking to either tryptophan or cysteine.	tmpzr1t_l9r_go_relaxed.owl						See also the biological process term 'peptide cross-linking via 4'-(L-tryptophan)-L-tryptophyl quinone ; GO:0018069'.								biological_process											owl:Class	
GO:0000419	biolink:NamedThing	RNA polymerase V complex	RNA polymerase V is a multisubunit RNA polymerase complex found in the nucleus of plants and involved in accumulation of siRNAs and in DNA methylation-dependent silencing of endogenous repeated sequences. Pol V is composed of subunits that are paralogous or identical to the 12 subunits of Pol II. Two large subunits comprise the most conserved portion including the catalytic site and share similarity with other eukaryotic and bacterial multisubunit RNA polymerases. The second largest subunit is also found in RNA polymerase IVa, while the largest subunit is found only in the IVa complex and contains an extended C-terminal domain (CTD) that includes multiple repeats of a 16 amino-acid consensus sequence as well as other sequences. The remainder of the complex is composed of smaller subunits.	tmpzr1t_l9r_go_relaxed.owl	DNA-directed RNA polymerase IVb complex|DNA-directed RNA polymerase V complex											GO:0080137		cellular_component											owl:Class	
GO:0004395	biolink:NamedThing	hexaprenyldihydroxybenzoate methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + 3-hexaprenyl-4,5-dihydroxybenzoate = S-adenosyl-L-homocysteine + 3-hexaprenyl-4-hydroxy-5-methoxybenzoate.	tmpzr1t_l9r_go_relaxed.owl	DHHB methyltransferase activity|S-adenosyl-L-methionine:3-hexaprenyl-4,5-dihydroxylate O-methyltransferase activity|DHHB-Mt activity|dihydroxyhexaprenylbenzoate methyltransferase activity|3,4-dihydroxy-5-hexaprenylbenzoate methyltransferase activity				RHEA:14121|MetaCyc:2.1.1.114-RXN|EC:2.1.1.114									molecular_function											owl:Class	
GO:0102898	biolink:NamedThing	levopimaradienol hydroxylase activity	Catalysis of the reaction: H+ + levopimaradienol + NADPH + O2 <=> levopiramadiene-diol + NADP + H2O.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-8517									molecular_function											owl:Class	
GO:0062066	biolink:NamedThing	PSII associated light-harvesting complex II binding	Binding to a PSII associated light-harvesting complex II.	tmpzr1t_l9r_go_relaxed.owl								dph	2018-08-31T14:06:01Z					molecular_function											owl:Class	
GO:0019772	biolink:NamedThing	low-affinity IgG receptor activity	Combining with low affinity with an immunoglobulin of an IgG isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	low affinity IgG receptor activity|low affinity Fc receptor activity													molecular_function											owl:Class	
GO:0035524	biolink:NamedThing	proline transmembrane transport	The directed movement of proline, pyrrolidine-2-carboxylic acid, across a membrane by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	proline membrane transport					Note that this term is not intended for use in annotating lateral movement within membranes.		bf	2010-05-04T04:52:46Z					biological_process											owl:Class	
GO:0046543	biolink:NamedThing	development of secondary female sexual characteristics	The process whose specific outcome is the progression of the secondary female sexual characteristics over time, from their formation to the mature structures. In female humans, these include growth of axillary and pubic hair, breast development and menstrual periods. Their development occurs in response to sex hormone secretion.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0018150	biolink:NamedThing	peptide cross-linking via 3-(3'-L-histidyl)-L-tyrosine	The modification of peptidyl-histidine and peptidyl-tyrosine to form a 3-(3'-L-histidyl)-L-tyrosine protein cross-link.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0250									biological_process											owl:Class	
GO:0055005	biolink:NamedThing	ventricular cardiac myofibril assembly	The process whose specific outcome is the progression of the ventricular cardiac myofibril over time, from its formation to the mature structure. A cardiac myofibril is a myofibril specific to cardiac muscle cells.	tmpzr1t_l9r_go_relaxed.owl	ventricular cardiac myofibril development|ventricular heart myofibril development													biological_process											owl:Class	
GO:0140638	biolink:NamedThing	small ribosomal subunit processing complex	A small heterodimeric protein complex that is required during early maturation of nascent 40S ribosomal subunits. The complex has endonuclease activity, it interacts with the small ribosomal subunit pre-rRNA and cleave it it to produce the mature 18S (or small ribosomal subunit) rRNA. In S. cerevisiae it is composed of Rcl1p and Bms1p.	tmpzr1t_l9r_go_relaxed.owl	small ribosomal subunit maturation complex	https://github.com/geneontology/go-ontology/issues/15290						pg	2021-04-21T08:07:11Z					cellular_component											owl:Class	
GO:0050481	biolink:NamedThing	mandelate 4-monooxygenase activity	Catalysis of the reaction: (S)-mandelate + 5,6,7,8-tetrahydrobiopterin + O(2) = (S)-4-hydroxymandelate + 7,8-dihydrobiopterin + H(2)O. (S)-2-hydroxy-2-phenylacetate is also known as S-mandelate.	tmpzr1t_l9r_go_relaxed.owl	(S)-2-hydroxy-2-phenylacetate,tetrahydrobiopterin:oxygen oxidoreductase (4-hydroxylating)|L-mandelate 4-hydroxylase activity|mandelic acid 4-hydroxylase activity				KEGG_REACTION:R03794|RHEA:21716|MetaCyc:MANDELATE-4-MONOOXYGENASE-RXN|EC:1.14.16.6									molecular_function											owl:Class	
GO:0043135	biolink:NamedThing	5-phosphoribosyl 1-pyrophosphate pyrophosphatase activity	Catalysis of the reaction: 5-phospho-alpha-D-ribose 1-diphosphate + H2O = ribose 1,5 bisphosphate + phosphate + H+.	tmpzr1t_l9r_go_relaxed.owl	PRPP pyrophosphatase activity				MetaCyc:RXN-10969									molecular_function											owl:Class	
GO:0102094	biolink:NamedThing	S-adenosylmethionine:2-demethylmenaquinol methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine  + a demethylmenaquinol <=> S-adenosyl-L-homocysteine  + H+ + a menaquinol.	tmpzr1t_l9r_go_relaxed.owl					EC:2.1.1.163|MetaCyc:RXN-11046|RHEA:26466									molecular_function											owl:Class	
GO:0070677	biolink:NamedThing	rRNA (cytosine-2'-O-)-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing 2'-O-methylcytosine.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-05-29T03:37:53Z					molecular_function											owl:Class	
GO:0090706	biolink:NamedThing	specification of plant organ position	The regionalization process in which information that determines the correct position at which plant organ primordia are formed is generated and perceived resulting in correct positioning of the new plant organ.	tmpzr1t_l9r_go_relaxed.owl								tb	2016-10-05T12:33:21Z					biological_process											owl:Class	
GO:0001637	biolink:NamedThing	G protein-coupled chemoattractant receptor activity	Combining with a chemoattractant and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.	tmpzr1t_l9r_go_relaxed.owl	G-protein coupled chemoattractant receptor activity|G protein chemoattractant receptor activity|G-protein chemoattractant receptor activity													molecular_function											owl:Class	
GO:0033452	biolink:NamedThing	GUG codon-amino acid adaptor activity	A triplet codon-amino acid adaptor activity that recognizes a GUG codon.	tmpzr1t_l9r_go_relaxed.owl	GTG codon-amino acid adaptor activity|valine tRNA					Note that in the standard genetic code, GTG codes for valine.								molecular_function											owl:Class	
GO:0102531	biolink:NamedThing	ecdysteroid-phosphate phosphatase activity	Catalysis of the reaction: H2O + an ecdysteroid 22-phosphate = hydrogenphosphate + an ecdysteroid.	tmpzr1t_l9r_go_relaxed.owl					RHEA:63576|MetaCyc:RXN-14734									molecular_function											owl:Class	
GO:0006711	biolink:NamedThing	estrogen catabolic process	The chemical reactions and pathways resulting in the breakdown of estrogens, C18 steroid hormones that can stimulate the development of female sexual characteristics. Also found in plants.	tmpzr1t_l9r_go_relaxed.owl	estrogen degradation|oestrogen catabolism|estrogen breakdown|estrogen catabolism|oestrogen catabolic process													biological_process											owl:Class	
GO:0040027	biolink:NamedThing	negative regulation of vulval development	Any process that stops, prevents, or reduces the frequency, rate or extent of development of the vulva. Vulval development is the process whose specific outcome is the progression of the egg-laying organ of female and hermaphrodite nematodes over time, from its formation to the mature structure. In nematodes, the vulva is formed from ventral epidermal cells during larval stages to give rise to a fully formed vulva in the adult.	tmpzr1t_l9r_go_relaxed.owl	down regulation of vulval development|down-regulation of vulval development|downregulation of vulval development|inhibition of vulval development													biological_process											owl:Class	
GO:0000474	biolink:NamedThing	maturation of SSU-rRNA from tetracistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, 2S rRNA, LSU-rRNA)	Any process involved in the maturation of a precursor Small SubUnit (SSU) ribosomal RNA (rRNA) molecule into a mature SSU-rRNA molecule from the pre-rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, 5.8 S rRNA, 2S rRNA, and Large Subunit (LSU) in that order from 5' to 3' along the primary transcript.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0018570	biolink:NamedThing	p-cumate 2,3-dioxygenase activity	Catalysis of the reaction: p-cumate + NADH + H+ + O2 = NAD+ + cis-2,3-dihydroxy-2,3-dihydro-p-cumate.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-664|EC:1.14.12.25|UM-BBD_reactionID:r0395|RHEA:42344									molecular_function											owl:Class	
GO:0047899	biolink:NamedThing	formate dehydrogenase (NADP+) activity	Catalysis of the reaction: formate + NADP(+) = CO(2) + NADPH.	tmpzr1t_l9r_go_relaxed.owl	formate:NADP+ oxidoreductase activity|NADP-dependent formate dehydrogenase activity				KEGG_REACTION:R00134|MetaCyc:FORMATE-DEHYDROGENASE-NADP+-RXN|EC:1.17.1.10|RHEA:12000									molecular_function											owl:Class	
GO:0140364	biolink:NamedThing	GW body	A ribonucleoprotein granule located in the cytoplasm and the nucleus. GW-bodies minimally contain the Argonaute2 (Ago2) and TNRC6B proteins, together with specific target RNAs.	tmpzr1t_l9r_go_relaxed.owl	GW-body							pg	2019-07-25T19:26:48Z					cellular_component											owl:Class	
GO:0009995	biolink:NamedThing	soluble molecule recognition	The recognition of soluble molecules in the environment.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0080083	biolink:NamedThing	beta-gentiobiose beta-glucosidase activity	Catalysis of the hydrolysis of glucosidic link in beta-gentiobiose.	tmpzr1t_l9r_go_relaxed.owl								dhl	2009-04-14T04:10:14Z					molecular_function											owl:Class	
GO:0034929	biolink:NamedThing	1-hydroxypyrene 7,8-monooxygenase activity	Catalysis of the reaction: 1-hydroxypyrene + O2 + 2 H+ + 2 e- = 1-hydroxypyrene-7,8-oxide + H2O.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0949									molecular_function											owl:Class	
GO:0003837	biolink:NamedThing	beta-ureidopropionase activity	Catalysis of the reaction: N-carbamoyl-beta-alanine + H2O = beta-alanine + CO2 + NH3.	tmpzr1t_l9r_go_relaxed.owl	N-carbamoyl-beta-alanine amidohydrolase activity				RHEA:11184|EC:3.5.1.6|MetaCyc:BETA-UREIDOPROPIONASE-RXN|Reactome:R-HSA-73620|Reactome:R-HSA-73591									molecular_function											owl:Class	
GO:0042603	biolink:NamedThing	capsule	A protective structure surrounding some fungi and bacteria, attached externally to the cell wall and composed primarily of polysaccharides. Capsules are highly organized structures that adhere strongly to cells and cannot be easily removed. Capsules play important roles in pathogenicity, preventing phagocytosis by other cells, adherance, and resistance to dessication.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Capsule_(microbiology)							GO:0030113|GO:0042604		cellular_component											owl:Class	
GO:0034640	biolink:NamedThing	establishment of mitochondrion localization by microtubule attachment	The directed movement of a mitochondrion by attachment to a microtubule, followed by elongation of the microtubule by tubulin polymerization.	tmpzr1t_l9r_go_relaxed.owl	mitochondrial localization by microtubule attachment|mitochondrion migration by microtubule attachment|establishment of mitochondrion localisation by microtubule attachment|mitochondrial migration by microtubule attachment													biological_process											owl:Class	
GO:0008826	biolink:NamedThing	cysteine sulfinate desulfinase activity	Catalysis of the reaction: 3-sulfinoalanine = L-alanine + sulfite.	tmpzr1t_l9r_go_relaxed.owl	cysteine sulphinate desulphinase activity				MetaCyc:RXN0-279|RHEA:28278									molecular_function											owl:Class	
GO:0034946	biolink:NamedThing	3-isopropylbut-3-enoyl-CoA thioesterase activity	Catalysis of the reaction: 3-isopropylbut-3-enoyl-CoA + H2O = 3-isopropylbut-3-enoic acid + CoASH.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0994									molecular_function											owl:Class	
GO:0098638	biolink:NamedThing	laminin binding involved in cell-matrix adhesion	Any laminin protein binding that occurs as part of cell-matrix adhesion.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0002402	biolink:NamedThing	B cell tolerance induction in mucosal-associated lymphoid tissue	Tolerance induction taking place in the mucosal-associated lymphoid tissue (MALT) mediated by B cells.	tmpzr1t_l9r_go_relaxed.owl	B cell tolerance induction in MALT													biological_process											owl:Class	
GO:0071187	biolink:NamedThing	protocadherin-alpha-v4-protocadherin-gamma-b4 complex	A protein complex that contains the cell adhesion molecules protocadherin-alpha-v4 and protocadherin-gamma-b4, and is involved in the regulation of protein localization to the plasma membrane.	tmpzr1t_l9r_go_relaxed.owl	Pcdhga1-Pcdhgb4 complex							mah	2009-11-23T04:22:08Z					cellular_component											owl:Class	
GO:0062187	biolink:NamedThing	anandamide 8,9 epoxidase activity	Catalysis of the reaction: N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine + O2 + reduced [NADPH--hemoprotein reductase] = H(+) + H2O + N-(8,9-epoxy-5Z,11Z,14Z-eicosatrienoyl)-ethanolamine + oxidized [NADPH--hemoprotein reductase].	tmpzr1t_l9r_go_relaxed.owl					RHEA:53140			dph	2019-11-26T18:51:34Z					molecular_function											owl:Class	
GO:0003959	biolink:NamedThing	NADPH dehydrogenase activity	Catalysis of the reaction: NADPH + H+ + acceptor = NADP+ + reduced acceptor.	tmpzr1t_l9r_go_relaxed.owl	reduced nicotinamide adenine dinucleotide phosphate dehydrogenase activity|triphosphopyridine nucleotide diaphorase activity|triphosphopyridine diaphorase activity|NADPH:(acceptor) oxidoreductase activity|NADPH:acceptor oxidoreductase activity|TPNH-diaphorase activity|NADPH2 diaphorase activity|NADPH diaphorase activity|NADPH2-dehydrogenase activity|old yellow enzyme|OYE|NADPH-dehydrogenase activity|dihydronicotinamide adenine dinucleotide phosphate dehydrogenase activity|TPNH dehydrogenase activity				Reactome:R-HSA-9018867|RHEA:13149|Reactome:R-HSA-9027632|UM-BBD_enzymeID:e0523|MetaCyc:NADPH-DEHYDROGENASE-RXN|Reactome:R-HSA-9018901|Reactome:R-HSA-9027625|EC:1.6.99.1|Reactome:R-HSA-9027631							GO:0008468|GO:0016660		molecular_function											owl:Class	
GO:0047310	biolink:NamedThing	glutamine-scyllo-inositol transaminase activity	Catalysis of the reaction: 2,4,6/3,5-pentahydroxycyclohexanone + L-glutamine = 1-amino-1-deoxy-scyllo-inositol + 2-oxoglutaramate.	tmpzr1t_l9r_go_relaxed.owl	glutamine-scyllo-inosose aminotransferase activity|glutamine-scyllo-inosose transaminase activity|L-glutamine:2,4,6/3,5-pentahydroxycyclohexanone aminotransferase activity|glutamine--scyllo-inosose transaminase activity|L-glutamine-scyllo-inosose transaminase activity|glutamine--scyllo-inosose aminotransferase activity|glutamine scyllo-inosose aminotransferase activity|L-glutamine-keto-scyllo-inositol aminotransferase activity				KEGG_REACTION:R02781|MetaCyc:2.6.1.50-RXN|RHEA:22920|EC:2.6.1.50									molecular_function											owl:Class	
GO:0046936	biolink:NamedThing	2'-deoxyadenosine deaminase activity	Catalysis of the reaction: 2'-deoxyadenosine + H2O = deoxyinosine + NH3.	tmpzr1t_l9r_go_relaxed.owl	deoxyadenosine deaminase reaction				MetaCyc:ADDALT-RXN|RHEA:28190									molecular_function											owl:Class	
GO:0102987	biolink:NamedThing	palmitoleic acid delta 12 desaturase activity	Catalysis of the reaction: palmitoleoyl-CoA + O2 + a reduced electron acceptor <=> (9Z,12Z)-hexadecadienoyl-CoA + 2 H2O + an oxidized electron acceptor.	tmpzr1t_l9r_go_relaxed.owl					RHEA:45096|MetaCyc:RXN-9616									molecular_function											owl:Class	
GO:0002491	biolink:NamedThing	antigen processing and presentation of endogenous peptide antigen via MHC class II	The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class II protein complex. The peptide antigen is typically, but not always, processed from a whole protein.	tmpzr1t_l9r_go_relaxed.owl	endogenous peptide antigen processing and presentation via MHC class II													biological_process											owl:Class	
GO:0102350	biolink:NamedThing	trans-cerot-2-enoyl-CoA reductase activity	Catalysis of the reaction: hexacosanoyl-CoA(4-) + NADP(3-) <=> trans-2-hexacosenoyl-CoA + NADPH + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-13309									molecular_function											owl:Class	
GO:0006102	biolink:NamedThing	isocitrate metabolic process	The chemical reactions and pathways involving isocitrate, the anion of isocitric acid, 1-hydroxy-1,2,3-propanetricarboxylic acid. Isocitrate is an important intermediate in the TCA cycle and the glycoxylate cycle.	tmpzr1t_l9r_go_relaxed.owl	isocitrate metabolism													biological_process											owl:Class	
GO:0010478	biolink:NamedThing	chlororespiration	A respiratory electron flow (from NAD(P)H to plastoquinone (PQ) and O2) involving both a nonphotochemical reduction and re-oxidation of PQ pool.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0102279	biolink:NamedThing	lecithin:11-cis retinol acyltransferase activity	Catalysis of the reaction: an 11-cis retinol-[cellular-retinol-binding-protein] + a phosphatidylcholine <=> a cellular-retinol-binding protein + an 11-cis-retinyl ester + a 1-lysophosphatidylcholine.	tmpzr1t_l9r_go_relaxed.owl					EC:2.3.1.135|MetaCyc:RXN-12563									molecular_function											owl:Class	
GO:0002530	biolink:NamedThing	regulation of systemic arterial blood pressure involved in acute-phase response	Any process that modulates the force with which blood travels through the circulatory system that contributes to the acute phase response. The acute phase response occurs during the early phases of an infection and is marked by changes in the production of plasma proteins such as C-reactive protein.	tmpzr1t_l9r_go_relaxed.owl	regulation of systemic arterial blood pressure during acute phase response|blood pressure regulation during acute phase response													biological_process											owl:Class	
GO:0006296	biolink:NamedThing	nucleotide-excision repair, DNA incision, 5'-to lesion	The endonucleolytic cleavage of the damaged strand of DNA 5' to the site of damage. The incision occurs at the junction of single-stranded DNA and double-stranded DNA that is formed when the DNA duplex is unwound. The incision follows the incision formed 3' to the site of damage.	tmpzr1t_l9r_go_relaxed.owl	nucleotide-excision repair, DNA incision, 5' to lesion													biological_process											owl:Class	
GO:0098979	biolink:NamedThing	polyadic synapse	A synapse consisting of a single presynapse and multiple postsynapses.  These postsynapses may come from the same cell of from different cells. Polyadic synapses are common in arthropod and nematode central nervous systems.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0031760	biolink:NamedThing	Edg-7 lysophosphatidic acid receptor binding	Binding to an Edg-7 lysophosphatidic acid receptor.	tmpzr1t_l9r_go_relaxed.owl	LPA3 receptor binding|Edg-7 lysophosphatidic acid receptor ligand													molecular_function											owl:Class	
GO:0000110	biolink:NamedThing	nucleotide-excision repair factor 1 complex	One of several protein complexes involved in nucleotide-excision repair; possesses DNA damage recognition and endodeoxynuclease activities. In S. cerevisiae, it is composed of Rad1p, Rad10p, and Rad14p; in human the subunits are ERCC4/XPF, ERCC1 and XPA, respectively.	tmpzr1t_l9r_go_relaxed.owl	NEF1 complex|XPA-ERCC1-ERCC4 complex					Note that process and function information are included in the term and definition for the purpose of describing and distinguishing the complex.								cellular_component											owl:Class	
GO:0021981	biolink:NamedThing	subpallium radially oriented migration	The migration of cells in the developing subpallium in which cells move from the ventricular and/or subventricular zone toward the surface of the brain.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0009017	biolink:NamedThing	succinylglutamate desuccinylase activity	Catalysis of the reaction: N-succinyl-L-glutamate + H(2)O = L-glutamate + succinate.	tmpzr1t_l9r_go_relaxed.owl	AstE|N2-succinylglutamate desuccinylase activity|SGDS|N-succinyl-L-glutamate amidohydrolase activity				KEGG_REACTION:R00411|RHEA:15169|MetaCyc:SUCCGLUDESUCC-RXN|EC:3.5.1.96									molecular_function											owl:Class	
GO:0052755	biolink:NamedThing	reduced coenzyme F420:quinone oxidoreductase activity	Catalysis of the reaction: reduced coenzyme F420 + 2,3-dimethyl-1,4-naphthoquinone = coenzyme F420 + reduced 2,3-dimethyl-1,4-naphthoquinone. Reduced 2,3-dimethyl-1,4-naphthoquinone is also known as 2,3-dimethyl-1,4-hydronaphthoquinone.	tmpzr1t_l9r_go_relaxed.owl	F420H2:2,3-dimethyl-1,4-naphthoquinone oxidoreductase activity|F420H2-dependent quinone oxidoreductase activity|F420H2:quinone oxidoreductase activity							ai	2011-09-22T04:08:13Z					molecular_function											owl:Class	
GO:0051913	biolink:NamedThing	regulation of synaptic plasticity by chemical substance	The process in which a chemical substance modulates synaptic plasticity, the ability of synapses to change as circumstances require.	tmpzr1t_l9r_go_relaxed.owl	regulation of synaptic plasticity by drug													biological_process											owl:Class	
GO:0097456	biolink:NamedThing	terminal loop	Portion of myelin-forming Schwann cell consisting of terminal cytoplasmic extensions adhered to the axon at the beginning and end of the myelin sheath.	tmpzr1t_l9r_go_relaxed.owl	terminal loop of Schwann cell				NIF_Subcellular:sao924713546			pr	2012-12-19T13:04:06Z					cellular_component											owl:Class	
GO:0005457	biolink:NamedThing	GDP-fucose transmembrane transporter activity	Enables the transfer of a GDP-fucose from one side of a membrane to the other. GDP-fucose is a substance composed of fucose in glycosidic linkage with guanosine diphosphate.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-5653596|Reactome:R-HSA-742345									molecular_function											owl:Class	
GO:1990223	biolink:NamedThing	positive regulation by symbiont of cytokinin levels in host	Any process in which an organism activates, maintains or increases the frequency, rate or extent of the cytokinin levels in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl								ml	2013-10-16T15:27:27Z					biological_process											owl:Class	
GO:0046899	biolink:NamedThing	nucleoside triphosphate adenylate kinase activity	Catalysis of the reaction: nucleoside triphosphate + AMP = nucleoside diphosphate + ADP.	tmpzr1t_l9r_go_relaxed.owl	nucleoside-triphosphate-adenylate kinase activity|nucleoside-triphosphate:AMP phosphotransferase activity|guanosine triphosphate-adenylate kinase|nucleoside triphosphate-adenosine monophosphate transphosphorylase activity|GTP:AMP phosphotransferase|isozyme 3 of adenylate kinase activity				MetaCyc:2.7.4.10-RXN|Reactome:R-HSA-1008248|EC:2.7.4.10|RHEA:13749									molecular_function											owl:Class	
GO:1901345	biolink:NamedThing	response to L-thialysine	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-thialysine stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to thialysine							mah	2012-09-07T13:22:49Z					biological_process											owl:Class	
GO:0061485	biolink:NamedThing	memory T cell proliferation	The expansion of a memory T cell population by cell division.	tmpzr1t_l9r_go_relaxed.owl								dph	2012-12-04T09:52:54Z					biological_process											owl:Class	
GO:0099085	biolink:NamedThing	DIF dechlorinase activity	Catalysis of the reaction: 1-[(3,5-dichloro-2,6-dihydroxy-4-methoxy)phenyl]hexan-1-one => 1-[(3-chloro-2,6-dihydroxy-4-methoxy)phenyl]hexan-1-one + Cl-.	tmpzr1t_l9r_go_relaxed.owl	DIF-1 3(5)-dechlorinase activity|1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one 3(5)-dechlorinase activity|1-[(3,5-dichloro-2,6-dihydroxy-4-methoxy)phenyl]hexan-1-one 3(5)-dechlorinase activity|differentiation-inducing factor 1 dechlorinase activity|DIF-1 dechlorinase activity|differentiation-inducing factor dechlorinase activity													molecular_function											owl:Class	
GO:0001641	biolink:NamedThing	group II metabotropic glutamate receptor activity	A G protein-coupled receptor that is activated by trans-1-aminocyclopentane-1,3-dicarboxylic acid (t-ACPD) and inhibits adenylate cyclase activity.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1904550	biolink:NamedThing	response to arachidonic acid	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an arachidonic acid stimulus.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-08-13T20:53:24Z					biological_process											owl:Class	
GO:1990616	biolink:NamedThing	magnesium ion export from mitochondrion	The directed movement of magnesium ions out of mitochondrial matrix into the cytosol by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	magnesium ion efflux from mitochondrion							mcc	2015-01-21T22:06:42Z					biological_process											owl:Class	
GO:0030623	biolink:NamedThing	U5 snRNA binding	Binding to a U5 small nuclear RNA (U5 snRNA).	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0009727	biolink:NamedThing	detection of ethylene stimulus	The series of events in which an ethylene (ethene) stimulus is received by a cell and converted into a molecular signal.	tmpzr1t_l9r_go_relaxed.owl	perception of ethylene stimulus|perception of ethene stimulus|detection of ethene stimulus													biological_process											owl:Class	
GO:0050111	biolink:NamedThing	mycocerosate synthase activity	Catalysis of the reaction: acyl-CoA + 7n H(+) + n methylmalonyl-CoA + 2n NADPH = n CO(2) + n CoA + n H(2)O + multi-methyl-branched acyl-CoA + 2n NADP(+).	tmpzr1t_l9r_go_relaxed.owl	mycocerosic acid synthase activity|acyl-CoA:methylmalonyl-CoA C-acyltransferase (decarboxylating, oxoacyl- and enoyl-reducing)				EC:2.3.1.111|KEGG_REACTION:R05189|MetaCyc:MYCOCEROSATE-SYNTHASE-RXN|RHEA:10588									molecular_function											owl:Class	
GO:0047735	biolink:NamedThing	cellobiose dehydrogenase (acceptor) activity	Catalysis of the reaction: cellobiose + acceptor = cellobiono-1,5-lactone + reduced acceptor.	tmpzr1t_l9r_go_relaxed.owl	cellobiose:oxygen 1-oxidoreductase activity|CDH activity|phanerochaete chrysosporium cellobiose oxidoreductase activity|cellobiose oxidoreductase activity|cellobiose:(acceptor) 1-oxidoreductase activity|cellobiose oxidase activity|cellobiose dehydrogenase (quinone) activity|cellobiose dehydrogenase activity|cellobiose:acceptor 1-oxidoreductase activity|cellobiose-quinone oxidoreductase activity|CBOR activity				RHEA:23484|EC:1.1.99.18|MetaCyc:CELLOBIOSE-DEHYDROGENASE-ACCEPTOR-RXN							GO:0047737		molecular_function											owl:Class	
GO:0004856	biolink:NamedThing	xylulokinase activity	Catalysis of the reaction: D-xylulose + ATP = D-xylulose 5-phosphate + ADP + 2 H(+).	tmpzr1t_l9r_go_relaxed.owl	xylulose kinase activity|xylulokinase (phosphorylating)|D-xylulokinase activity|ATP:D-xylulose 5-phosphotransferase activity				MetaCyc:XYLULOKIN-RXN|KEGG_REACTION:R01639|EC:2.7.1.17|Reactome:R-HSA-5662466|RHEA:10964									molecular_function											owl:Class	
GO:0140462	biolink:NamedThing	pericentric heterochromatin organization	The organization of chromatin into heterochromatin at the pericentric region of a chromosome.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/19396|https://github.com/geneontology/go-ontology/issues/22288						pg	2020-05-06T07:47:09Z					biological_process											owl:Class	
GO:0050403	biolink:NamedThing	trans-zeatin O-beta-D-glucosyltransferase activity	Catalysis of the reaction: trans-zeatin + UDP-D-glucose = O-beta-D-glucosyl-trans-zeatin + H(+) + UDP.	tmpzr1t_l9r_go_relaxed.owl	zeatin O-glucosyltransferase activity|UDP-glucose:trans-zeatin O-beta-D-glucosyltransferase activity|zeatin O-beta-D-glucosyltransferase activity|UDPglucose:trans-zeatin O-beta-D-glucosyltransferase activity|zeatin O-b-D-glucosyltransferase activity|uridine diphosphoglucose-zeatin O-glucosyltransferase activity				KEGG_REACTION:R02118|RHEA:23224|EC:2.4.1.203|MetaCyc:RXN-4723									molecular_function											owl:Class	
GO:0102701	biolink:NamedThing	tricyclene synthase activity	Catalysis of the reaction: geranyl diphosphate(3-) <=> tricyclene + diphosphoric acid.	tmpzr1t_l9r_go_relaxed.owl					RHEA:32687|EC:4.2.3.105|MetaCyc:RXN-5121									molecular_function											owl:Class	
GO:0018461	biolink:NamedThing	fluoren-9-ol dehydrogenase activity	Catalysis of the reaction: fluoren-9-ol + 2 NADP+ = fluoren-9-one + 2 NADPH + 2 H+.	tmpzr1t_l9r_go_relaxed.owl	fluoren-9-ol:NAD(P)+ oxidoreductase activity|9-fluorenol dehydrogenase activity				MetaCyc:9-FLUORENOL-DEHYDROGENASE-RXN|UM-BBD_reactionID:r0408|EC:1.1.1.256									molecular_function											owl:Class	
GO:0038152	biolink:NamedThing	C-C chemokine receptor CCR4 signaling pathway	A series of molecular signals initiated by a the C-C chemokine type 2 receptor (CCR4) on the surface of a cell binding to one of it's physiological ligands, and ending with regulation of a downstream cellular process, e.g. transcription.	tmpzr1t_l9r_go_relaxed.owl	C-C chemokine receptor type 4 signaling pathway|chemokine receptor CCR4 signaling pathway							bf	2012-05-11T11:43:34Z					biological_process											owl:Class	
GO:0060430	biolink:NamedThing	lung saccule development	The biological process whose specific outcome is the progression of a lung saccule from an initial condition to its mature state. The lung saccule is the primitive gas exchange portion of the lung composed of type I and type II cells.	tmpzr1t_l9r_go_relaxed.owl	lung saccular development													biological_process											owl:Class	
GO:0140538	biolink:NamedThing	negative regulation of conjugation with zygote	A process that prevents a zygote from fusing an additional cell.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/16329						pg	2020-11-07T07:50:23Z					biological_process											owl:Class	
GO:0061483	biolink:NamedThing	sulfinylpropanyl adenylate synthase	Catalysis of the reaction: cysteine sulfanate + GTP + IMP = sulfinylpropanyl adenylate + GDP + 3 H(+) + phosphate.	tmpzr1t_l9r_go_relaxed.owl	SPA synthase							dph	2012-11-16T10:08:15Z					molecular_function											owl:Class	
GO:0009934	biolink:NamedThing	regulation of meristem structural organization	Any process that modulates the frequency, rate or extent of meristem organization.	tmpzr1t_l9r_go_relaxed.owl	regulation of meristem organization|regulation of meristem organisation													biological_process											owl:Class	
GO:0097493	biolink:NamedThing	structural molecule activity conferring elasticity	The action of a molecule that contributes to the structural integrity of a complex or assembly within or outside a cell, providing elasticity and recoiling.	tmpzr1t_l9r_go_relaxed.owl								pr	2013-07-26T09:47:26Z					molecular_function											owl:Class	
GO:0061486	biolink:NamedThing	high-affinity fructose transmembrane transporter activity	Enables the transfer of fructose from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.	tmpzr1t_l9r_go_relaxed.owl	high affinity fructose transmembrane transporter activity							dph	2012-12-04T10:34:55Z					molecular_function											owl:Class	
GO:0047462	biolink:NamedThing	phenylalanine racemase (ATP-hydrolyzing) activity	Catalysis of the reaction: L-phenylalanine + ATP + H(2)O = D-phenylalanine + AMP + diphosphate + 2 H(+).	tmpzr1t_l9r_go_relaxed.owl	phenylalanine racemase (adenosine triphosphate-hydrolysing)|gramicidin S synthetase I|phenylalanine racemase (ATP-hydrolysing)|phenylalanine racemase activity				EC:5.1.1.11|MetaCyc:5.1.1.11-RXN|RHEA:20201|KEGG_REACTION:R00686									molecular_function											owl:Class	
GO:0009050	biolink:NamedThing	glycopeptide catabolic process	The chemical reactions and pathways resulting in the breakdown of glycopeptides, a compound in which carbohydrate is covalently attached to an oligopeptide composed of residues of L and/or D-amino acids. The term usually denotes a product of proteolytic degradation of a glycoprotein but includes glycated peptide.	tmpzr1t_l9r_go_relaxed.owl	glycopeptide breakdown|glycopeptide catabolism|glycopeptide degradation													biological_process											owl:Class	
GO:0043786	biolink:NamedThing	cinnamate reductase activity	Catalysis of the reaction: 3-phenylpropanoate + NAD+ = (E)-cinnamate + NADH + H+.	tmpzr1t_l9r_go_relaxed.owl					EC:1.3.1.-									molecular_function											owl:Class	
GO:0106149	biolink:NamedThing	indole-3-carbonyl nitrile 4-hydroxylase activity	Catalysis of the reaction: indole-3-carbonyl nitrile + NADPH +O2=4-hydroxyindole-3- carbonyl nitrile + NADP(+) + H20.	tmpzr1t_l9r_go_relaxed.owl					RHEA:57864|EC:1.14.14.165			hjd	2018-09-10T19:44:15Z					molecular_function											owl:Class	
GO:0034722	biolink:NamedThing	gamma-glutamyl-peptidase activity	Catalysis of the cleavage of a gamma-linked glutamate bond.	tmpzr1t_l9r_go_relaxed.owl	gamma-glutamyl hydrolase activity				RHEA:56784|MetaCyc:3.4.19.9-RXN|EC:3.4.19.9									molecular_function											owl:Class	
GO:0019031	biolink:NamedThing	viral envelope	The lipid bilayer of a virion that surrounds the protein capsid. May also contain glycoproteins.	tmpzr1t_l9r_go_relaxed.owl	viral glycoprotein|viral outside membrane				Wikipedia:Viral_envelope									cellular_component											owl:Class	
GO:0015643	biolink:NamedThing	toxic substance binding	Binding to a toxic substance, a poisonous substance that causes damage to biological systems.	tmpzr1t_l9r_go_relaxed.owl	antitoxin activity|lipoprotein antitoxin													molecular_function											owl:Class	
GO:0047858	biolink:NamedThing	dihydroxyfumarate decarboxylase activity	Catalysis of the reaction: dihydroxyfumarate + H(+) = 2-hydroxy-3-oxopropanoate + CO(2).	tmpzr1t_l9r_go_relaxed.owl	dihydroxyfumarate carboxy-lyase activity|dihydroxyfumarate carboxy-lyase (tartronate-semialdehyde-forming)				MetaCyc:DIHYDROXYFUMARATE-DECARBOXYLASE-RXN|EC:4.1.1.54|KEGG_REACTION:R03127|RHEA:13845									molecular_function											owl:Class	
GO:0060096	biolink:NamedThing	serotonin secretion, neurotransmission	The regulated release of serotonin by a cell, in which released serotonin acts as a neurotransmitter.	tmpzr1t_l9r_go_relaxed.owl	serotonin release, neurotransmission													biological_process											owl:Class	
GO:0002032	biolink:NamedThing	desensitization of G protein-coupled receptor signaling pathway by arrestin	The process that inhibits the signaling function of a G protein-coupled receptor by uncoupling the receptor from its downstream G proteins.	tmpzr1t_l9r_go_relaxed.owl	arrestin-mediated desensitization of G-protein coupled receptor protein signaling pathway|arrestin mediated desensitisation of G-protein coupled receptor protein signalling pathway|arrestin mediated desensitization of G-protein coupled receptor protein signaling pathway|desensitization of G-protein coupled receptor protein signaling pathway by arrestin													biological_process											owl:Class	
GO:0047316	biolink:NamedThing	glutamine-phenylpyruvate transaminase activity	Catalysis of the reaction: keto-phenylpyruvate + L-glutamine = 2-oxoglutaramate + L-phenylalanine.	tmpzr1t_l9r_go_relaxed.owl	glutamine transaminase K activity|L-glutamine:phenylpyruvate aminotransferase activity|glutamine--phenylpyruvate aminotransferase activity|glutamine-phenylpyruvate aminotransferase activity				EC:2.6.1.64|MetaCyc:2.6.1.64-RXN|RHEA:17593|KEGG_REACTION:R01375									molecular_function											owl:Class	
GO:0106384	biolink:NamedThing	dGMP salvage	Any process which produces a dGMP from derivatives of it, without de novo synthesis.	tmpzr1t_l9r_go_relaxed.owl								hjd	2021-06-11T19:36:06Z					biological_process											owl:Class	
GO:0008692	biolink:NamedThing	3-hydroxybutyryl-CoA epimerase activity	Catalysis of the reaction: (S)-3-hydroxybutanoyl-CoA = (R)-3-hydroxybutanoyl-CoA.	tmpzr1t_l9r_go_relaxed.owl	3-hydroxybutanoyl-CoA 3-epimerase activity|3-hydroxyacyl-CoA epimerase activity|3-hydroxybutyryl coenzyme A epimerase activity				RHEA:21760|MetaCyc:OHBUTYRYL-COA-EPIM-RXN|EC:5.1.2.3									molecular_function											owl:Class	
GO:0071885	biolink:NamedThing	N-terminal protein N-methyltransferase activity	Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine (AdoMet) to the alpha-amino group of the N-terminal amino or imino acid residue of a protein substrate. For example, yeast Tae1p and mammalian family member METTL11A preferentially modify the N-terminal residue of substrates with the N-terminal sequence X-Pro-Lys, where X can be Pro, Ala, or Ser.	tmpzr1t_l9r_go_relaxed.owl	X-Pro-Lys N-terminal methyltransferase							mah	2010-09-13T04:53:57Z					molecular_function											owl:Class	
GO:1904615	biolink:NamedThing	cellular response to biphenyl	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biphenyl stimulus.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-08-27T19:08:49Z					biological_process											owl:Class	
GO:0035458	biolink:NamedThing	cellular response to interferon-beta	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-beta stimulus. Interferon-beta is a type I interferon.	tmpzr1t_l9r_go_relaxed.owl	cellular response to beta-1 interferon|cellular response to fiblaferon|cellular response to fibroblast interferon							bf	2010-04-16T11:10:40Z					biological_process											owl:Class	
GO:0048001	biolink:NamedThing	erythrose-4-phosphate dehydrogenase activity	Catalysis of the reaction: D-erythrose 4-phosphate + H(2)O + NAD(+) = 4-phospho-D-erythronate + 2 H(+) + NADH.	tmpzr1t_l9r_go_relaxed.owl	erythrose 4-phosphate dehydrogenase activity|D-erythrose 4-phosphate:NAD+ oxidoreductase activity|Epd dehydrogenase activity|E4P dehydrogenase activity|E4PDH|GapB				KEGG_REACTION:R01825|EC:1.2.1.72|MetaCyc:ERYTH4PDEHYDROG-RXN|RHEA:12056							GO:0033724		molecular_function											owl:Class	
GO:0098527	biolink:NamedThing	neuromuscular junction of somatic muscle	A neuromuscular junction in which the target muscle cell is a somatic muscle cell, such as those found in nematodes and arthropods.	tmpzr1t_l9r_go_relaxed.owl								dos	2013-10-14T12:07:05Z					cellular_component											owl:Class	
GO:0035610	biolink:NamedThing	protein side chain deglutamylation	The removal of a glutamate residue from the side chain of a protein. Glutamate side chains are added to glutamic acid residues within the primary protein sequence during polyglutamylation.	tmpzr1t_l9r_go_relaxed.owl	removal of posttranslational polyglutamylation|shortening of glutamate side chain							bf	2010-11-18T01:09:03Z					biological_process											owl:Class	
GO:0002195	biolink:NamedThing	2-methylthio-N-6-(cis-hydroxy)isopentenyl adenosine-tRNA biosynthesis	The chemical reactions and pathways involved in the biosynthesis of 2-methylthio-N-6-(cis-hydroxy)isopentenyl adenosine (ms2io6A), a modified nucleoside present in position 37 (adjacent to and 3' of the anticodon) of tRNAs.	tmpzr1t_l9r_go_relaxed.owl						In Salmonella typhimurium, 2-methylthio-N-6-(cis-hydroxy)isopentenyl adenosine (ms2io6A; also referred to as 2-methylthio cis-ribozeatin) is found in tRNA, most likely in the species that have ms2i6A in E. coli.		hjd	2011-08-31T02:20:06Z					biological_process											owl:Class	
GO:0004577	biolink:NamedThing	N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity	Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + N-acetyl-D-glucosaminyl-diphosphodolichol = UDP + N,N''-diacetylchitobiosyldiphosphodolichol.	tmpzr1t_l9r_go_relaxed.owl	uridine diphosphoacetylglucosamine-dolichylacetylglucosamine pyrophosphate acetylglucosaminyltransferase activity|UDP-GlcNAc:dolichyl-pyrophosphoryl-GlcNAc GlcNAc transferase activity|UDP-N-acetyl-D-glucosamine:N-acetyl-D-glucosaminyl-diphosphodolichol N-acetyl-D-glucosaminyltransferase activity|N,N'-diacetylchitobiosylpyrophosphoryldolichol synthase activity				MetaCyc:2.4.1.141-RXN|Reactome:R-HSA-446207|Reactome:R-HSA-5633241|RHEA:23380|EC:2.4.1.141									molecular_function											owl:Class	
GO:0102713	biolink:NamedThing	gibberellin A25 hydroxylase activity	Catalysis of the reaction: gibberellin A25 + 2-oxoglutarate(2-) + O2 <=> gibberellin A46 + succinate(2-) + carbon dioxide.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-6543									molecular_function											owl:Class	
GO:0004409	biolink:NamedThing	homoaconitate hydratase activity	Catalysis of the reaction: (-)-homoisocitrate = cis-homoaconitate + H(2)O.	tmpzr1t_l9r_go_relaxed.owl	(1R,2S)-1-hydroxybutane-1,2,4-tricarboxylate hydro-lyase [(Z)-but-1-ene-1,2,4-tricarboxylate-forming]|LysF|2-hydroxybutane-1,2,4-tricarboxylate hydro-lyase activity|Lys4|cis-homoaconitase activity|homoaconitase activity|HACN activity				EC:4.2.1.36|MetaCyc:HOMOACONITATE-HYDRATASE-RXN|RHEA:15485|KEGG_REACTION:R04371									molecular_function											owl:Class	
GO:0061116	biolink:NamedThing	ductus venosus closure	The morphogenesis process in which the ductus venosus changes to no longer permit blood flow after birth.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-05-17T07:21:53Z					biological_process											owl:Class	
GO:0010813	biolink:NamedThing	neuropeptide catabolic process	The chemical reactions and pathways resulting in the breakdown of neuropeptides. Neuropeptides are signaling peptides that travel across a synaptic junction.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0062092	biolink:NamedThing	Yae1-Lto1 complex	A cytosolic complex that functions as an substrate-specific adaptor, linking the cytosolic iron-sulfur protein assembly (CIA) targeting complex to apo-Rli1p, an ABC protein involved in ribosome recycling, facilitating Fe-S cluster insertion and the maturation of the Rli1p.	tmpzr1t_l9r_go_relaxed.owl								dph	2018-11-15T17:39:46Z					cellular_component											owl:Class	
GO:0047835	biolink:NamedThing	D-tryptophan N-acetyltransferase activity	Catalysis of the reaction: D-tryptophan + acetyl-CoA = N-acetyl-D-tryptophan + CoA + H(+).	tmpzr1t_l9r_go_relaxed.owl	acetyl-CoA:D-tryptophan N-acetyltransferase activity|D-tryptophan acetyltransferase activity|acetyl-CoA-D-tryptophan-alpha-N-acetyltransferase activity				KEGG_REACTION:R02481|RHEA:10060|MetaCyc:D-TRYPTOPHAN-N-ACETYLTRANSFERASE-RXN|EC:2.3.1.34									molecular_function											owl:Class	
GO:0140451	biolink:NamedThing	counting factor complex	A secreted multiprotein complex composed of 4 proteins, regulating group size during aggregation in cooperative development. An example of this complex is found in Dictyostelium discoideum.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/19220						pg	2020-04-15T08:52:26Z					cellular_component											owl:Class	
GO:0036158	biolink:NamedThing	outer dynein arm assembly	The aggregation, arrangement and bonding together of a set of components to form an axonemal dynein outer arm, an outer arm structure present on the outer doublet microtubules of ciliary and flagellar axonemes.	tmpzr1t_l9r_go_relaxed.owl	ODA assembly							bf	2012-03-21T02:25:01Z					biological_process											owl:Class	
GO:1900074	biolink:NamedThing	negative regulation of neuromuscular synaptic transmission	Any process that stops, prevents or reduces the frequency, rate or extent of neuromuscular synaptic transmission.	tmpzr1t_l9r_go_relaxed.owl	inhibition of neuromuscular synaptic transmission|down-regulation of neuromuscular synaptic transmission|down regulation of neuromuscular synaptic transmission|downregulation of neuromuscular synaptic transmission							kmv	2012-01-26T10:14:18Z					biological_process											owl:Class	
GO:0034805	biolink:NamedThing	benzo(a)pyrene-trans-11,12-dihydrodiol dehydrogenase activity	Catalysis of the reaction: benzo(a)pyrene-trans-11,12-dihydrodiol = 11,12-dihydroxybenzo(a)pyrene + 2 H+ + 2 e-.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r1121									molecular_function											owl:Class	
GO:0052847	biolink:NamedThing	inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity	Catalysis of the reaction: 1,5-bisdiphosphoinositol-1D-myo-inositol 2,3,4,6-tetrakisphosphate + H2O = 1-diphospho-1D-myo-inositol 2,3,4,5,6-pentakisphosphate + phosphate + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-10975			ai	2011-12-05T11:02:23Z					molecular_function											owl:Class	
GO:0071479	biolink:NamedThing	cellular response to ionizing radiation	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ionizing radiation stimulus. Ionizing radiation is radiation with sufficient energy to remove electrons from atoms and may arise from spontaneous decay of unstable isotopes, resulting in alpha and beta particles and gamma rays. Ionizing radiation also includes X-rays.	tmpzr1t_l9r_go_relaxed.owl	cellular response to ionising radiation|cellular response to ionizing radiation stimulus							mah	2009-12-18T02:00:31Z					biological_process											owl:Class	
GO:0042718	biolink:NamedThing	yolk granule	Discrete structures that partition the water-insoluble portion of the yolk of oocytes and ova, which may or may not be membrane enclosed.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0033366	biolink:NamedThing	protein localization to secretory granule	A process in which a protein is transported to, or maintained in, a location within a secretory granule.	tmpzr1t_l9r_go_relaxed.owl	protein localization in secretory granule|protein localisation in secretory granule													biological_process											owl:Class	
GO:0106035	biolink:NamedThing	protein maturation by [4Fe-4S] cluster transfer	The transfer of an assembled 4Fe-4S] cluster from a scaffold protein to an acceptor protein that contributes to the attainment of the full functional capacity of a protein.	tmpzr1t_l9r_go_relaxed.owl								hjd	2017-07-07T17:26:10Z					biological_process											owl:Class	
GO:1990030	biolink:NamedThing	pericellular basket	Ramification of basket cell axon surrounding cell bodies, forming the characteristic pericellular baskets from which the cell class derives its name.	tmpzr1t_l9r_go_relaxed.owl	peri-cellular basket|peri cellular basket				NIF_Subcellular:sao413722576			pr	2013-02-07T12:53:54Z					cellular_component											owl:Class	
GO:0018523	biolink:NamedThing	quinoline 2-oxidoreductase activity	Catalysis of the reaction: quinoline + acceptor + H2O = isoquinolin-1(2H)-one + reduced acceptor.	tmpzr1t_l9r_go_relaxed.owl	quinoline:acceptor 2-oxidoreductase (hydroxylating)				RHEA:17749|MetaCyc:1.3.99.17-RXN|UM-BBD_reactionID:r0045|EC:1.3.99.17									molecular_function											owl:Class	
GO:0004704	biolink:NamedThing	NF-kappaB-inducing kinase activity	Catalysis of the phosphorylation of the alpha or beta subunit of the inhibitor of kappaB kinase complex (IKK).	tmpzr1t_l9r_go_relaxed.owl	NIK													molecular_function											owl:Class	
GO:0051168	biolink:NamedThing	nuclear export	The directed movement of substances out of the nucleus.	tmpzr1t_l9r_go_relaxed.owl	nucleus export|substance nuclear export|export from nucleus													biological_process											owl:Class	
GO:0038046	biolink:NamedThing	G protein-coupled enkephalin receptor activity	Combining with an enkephalin, and transmitting the signal across the membrane by activating an associated G-protein. A enkephalin is a pentapeptide (Tyr-Gly-Gly-Phe-Met or Tyr-Gly-Gly-Phe-Leu) involved in regulating nociception in the body.	tmpzr1t_l9r_go_relaxed.owl	delta-opioid receptor activity|enkephalin receptor activity	https://github.com/geneontology/go-ontology/issues/21110						bf	2011-11-14T01:30:14Z					molecular_function											owl:Class	
GO:0033739	biolink:NamedThing	preQ1 synthase activity	Catalysis of the reaction: 7-aminomethyl-7-deazaguanine + 2 NADP(+) = 7-cyano-7-deazaguanine + 3 H(+) + 2 NADPH.	tmpzr1t_l9r_go_relaxed.owl	preQ0 oxidoreductase activity|7-aminomethyl-7-carbaguanine:NADP+ oxidoreductase activity|YkvM|preQ0 reductase activity|7-cyano-7-deazaguanine reductase activity|queuine:NADP+ oxidoreductase activity|queuine synthase activity|QueF				RHEA:13409|MetaCyc:RXN0-4022|KEGG_REACTION:R07605|EC:1.7.1.13									molecular_function											owl:Class	
GO:1902312	biolink:NamedThing	negative regulation of copper ion transmembrane transport	Any process that stops, prevents or reduces the frequency, rate or extent of copper ion transmembrane transport.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of copper cation transmembrane transport|down-regulation of copper cation transmembrane transport|inhibition of copper ion membrane transport|down-regulation of copper ion membrane transport|inhibition of copper ion transmembrane transport|down regulation of copper ion transmembrane transport|downregulation of copper ion transmembrane transport|downregulation of copper ion membrane transport|inhibition of copper cation transmembrane transport|downregulation of copper cation transmembrane transport|down regulation of copper ion membrane transport|down-regulation of copper ion transmembrane transport|down regulation of copper cation transmembrane transport|negative regulation of copper ion membrane transport							di	2013-07-19T20:59:37Z					biological_process											owl:Class	
GO:0031177	biolink:NamedThing	phosphopantetheine binding	Binding to phosphopantetheine, the vitamin pantetheine 4'-(dihydrogen phosphate).	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0052830	biolink:NamedThing	inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity	Catalysis of the reaction: inositol-1,3,4,6-tetrakisphosphate + H2O = inositol-1,3,4-trisphosphate + phosphate.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-1855171			ai	2011-11-29T10:56:59Z					molecular_function											owl:Class	
GO:0010407	biolink:NamedThing	non-classical arabinogalactan protein metabolic process	The chemical reactions and pathways involving a cell wall arabinogalactan II glycoprotein where other amino acids besides Hyp, Ala, Ser, Thr and Gly can be present and grouped into regions, such as a Cys-rich or Asn-rich domains.	tmpzr1t_l9r_go_relaxed.owl	non-classical arabinogalactan protein metabolism													biological_process											owl:Class	
GO:0033252	biolink:NamedThing	regulation of beta-lactamase activity	Any process that modulates the frequency, rate or extent of beta-lactamase activity, the hydrolysis of a beta-lactam to yield a substituted beta-amino acid.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0050016	biolink:NamedThing	kynurenine 7,8-hydroxylase activity	Catalysis of the reaction: kynurenate + donor-H2 + O2 = 7,8-dihydro-7,8-dihydroxykynurenate + acceptor.	tmpzr1t_l9r_go_relaxed.owl	kynurenate 7,8-hydroxylase activity|kynurenic acid hydroxylase activity|kynurenate,hydrogen-donor:oxygen oxidoreductase (hydroxylating)|kynurenic hydroxylase activity				RHEA:11968|MetaCyc:KYNURENINE-78-HYDROXYLASE-RXN|EC:1.14.99.2									molecular_function											owl:Class	
GO:0070732	biolink:NamedThing	spindle envelope	An organelle envelope that surrounds the chromosomes and the central part of the spindle apparatus during mitosis and meiosis; observed in many invertebrates. The spindle envelope consists of membrane layers, called parafusorial membranes, derived from endoplasmic reticulum membrane; in male meiosis it forms during prometaphase and persists until early in the ensuing interphase.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-06-18T12:00:59Z					cellular_component											owl:Class	
GO:0004024	biolink:NamedThing	alcohol dehydrogenase activity, zinc-dependent	Catalysis of the reaction: an alcohol + NAD+ = an aldehyde or ketone + NADH + H+, requiring the presence of zinc.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-71707									molecular_function											owl:Class	
GO:0006621	biolink:NamedThing	protein retention in ER lumen	The retention in the endoplasmic reticulum (ER) lumen of soluble resident proteins. Sorting receptors retrieve proteins with ER localization signals, such as KDEL and HDEL sequences or some transmembrane domains, that have escaped to the cis-Golgi network and return them to the ER. Abnormally folded proteins and unassembled subunits are also selectively retained in the ER.	tmpzr1t_l9r_go_relaxed.owl	maintenance of protein location in ER lumen													biological_process											owl:Class	
GO:0005546	biolink:NamedThing	phosphatidylinositol-4,5-bisphosphate binding	Binding to phosphatidylinositol-4,5-bisphosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 4' and 5' positions.	tmpzr1t_l9r_go_relaxed.owl	PtdIns(4,5)P2 binding|1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate binding|phosphatidylinositol 4,5-bisphosphate binding|PIP2 binding													molecular_function											owl:Class	
GO:0042629	biolink:NamedThing	mast cell granule	Coarse, bluish-black staining cytoplasmic granules, bounded by a plasma membrane and found in mast cells and basophils. Contents include histamine, heparin, chondroitin sulfates, chymase and tryptase.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0042422	biolink:NamedThing	norepinephrine catabolic process	The chemical reactions and pathways resulting in the breakdown of norepinephrine, a hormone secreted by the adrenal medulla, and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts in the central nervous system. It is also the demethylated biosynthetic precursor of epinephrine.	tmpzr1t_l9r_go_relaxed.owl	norepinephrine breakdown|norepinephrine degradation|noradrenaline catabolic process|levarterenol catabolic process|levarterenol catabolism|norepinephrine catabolism|noradrenaline catabolism				Wikipedia:Norepinephrine#Degradation									biological_process											owl:Class	
GO:1990666	biolink:NamedThing	PCSK9-LDLR complex	A protein complex consisting of the serine protease PCSK9 (proprotein convertase subtilisin/kexin-9) and a low-density lipoprotein receptor (LDLR). Interaction typically occurs through the epidermal growth factor-like repeat A (EGF-A) domain of the LDLR, and complex formation promotes degradation of the LDLR through the endosome/lysosome pathway.	tmpzr1t_l9r_go_relaxed.owl	PCSK9.LDLR complex|PCSK9:low-density lipoprotein receptor complex|PCSK9:EGF-A complex|PCSK9/LDL-R complex							bf	2015-03-02T10:19:15Z					cellular_component											owl:Class	
GO:0035377	biolink:NamedThing	transepithelial water transport	The directed movement of water (H2O) from one side of an epithelium to the other.	tmpzr1t_l9r_go_relaxed.owl								bf	2010-03-18T10:55:38Z					biological_process											owl:Class	
GO:0044338	biolink:NamedThing	canonical Wnt signaling pathway involved in mesenchymal stem cell differentiation	The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes involved in mesenchymal stem cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	canonical Wnt receptor signaling pathway involved in mesenchymal stem cell differentiation|canonical Wnt receptor signalling pathway involved in mesenchymal stem cell differentiation|canonical Wnt-activated signaling pathway involved in mesenchymal stem cell differentiation							jl	2010-08-20T03:43:36Z					biological_process											owl:Class	
GO:0052650	biolink:NamedThing	NADP-retinol dehydrogenase activity	Catalysis of the reaction: all-trans-retinol + NADP+ = all-trans-retinal + NADPH + H+.	tmpzr1t_l9r_go_relaxed.owl	all-trans retinal reductase activity|all-trans-retinol dehydrogenase activity|retinol dehydrogenase activity|retinol:NADP+ oxidoreductase activity|NADP(H)-dependent retinol dehydrogenase/reductase activity|retinol dehydrogenase [NADP+] activity				Reactome:R-HSA-5623643|EC:1.1.1.300|Reactome:R-HSA-74872|MetaCyc:RXN-10841|Reactome:R-HSA-2464803|Reactome:R-HSA-2466861|Reactome:R-HSA-2471670|Reactome:R-HSA-5419165|Reactome:R-HSA-5615668|Reactome:R-HSA-2464822|Reactome:R-HSA-2465921|KEGG_REACTION:R08379|Reactome:R-HSA-2465940|RHEA:25033									molecular_function											owl:Class	
GO:0032151	biolink:NamedThing	mitotic septin complex	A heterooligomeric septin complex that acts during mitotic cell division.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0051203	biolink:NamedThing	peptidyl-aspartic acid reduction to form L-aspartyl aldehyde	The reduction of peptidyl-aspartic acid to form peptidyl-L-aspartyl aldehyde, as found photosystem II P680 chlorophyll A apoprotein.	tmpzr1t_l9r_go_relaxed.owl	peptidyl-aspartic acid reduction to form L-beta-formylalanine|peptidyl-aspartic acid reduction to form L-aspartate-beta-semialdehyde				RESID:AA0373	See also UniProtKB:P04160.								biological_process											owl:Class	
GO:0030493	biolink:NamedThing	bacteriochlorophyll metabolic process	The chemical reactions and pathways involving a bacteriochlorophyll, any of the chlorophylls of photosynthetic bacteria. They differ structurally from the chlorophylls of higher plants.	tmpzr1t_l9r_go_relaxed.owl	bacteriochlorophyll metabolism													biological_process											owl:Class	
GO:0010345	biolink:NamedThing	suberin biosynthetic process	The chemical reactions and pathways resulting in the formation of suberin monomers and suberin polyesters. Suberin monomers are derived from fatty acids and trans-cinnamic acids. The monomers are then cross-linked with glycerols.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:PWY-1121									biological_process											owl:Class	
GO:0035384	biolink:NamedThing	thioester biosynthetic process	The chemical reactions and pathways resulting in the formation of a thioester, a compound of general formula RC(=O)SR' in which the linking oxygen in an ester is replaced by a sulfur atom. They are the product of esterification between a carboxylic acid and a thiol.	tmpzr1t_l9r_go_relaxed.owl	thioester biosynthesis|thioester synthesis|thioester anabolism|thioester formation							bf	2010-03-18T01:52:11Z					biological_process											owl:Class	
GO:0034853	biolink:NamedThing	2,4,4-trimethyl-3-oxopentanoate decarboxylase activity	Catalysis of the reaction: 2,4,4-trimethyl-3-oxopentanoate + H+ = 2,2-dimethyl-3-pentanone + CO2.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r1278									molecular_function											owl:Class	
GO:0043261	biolink:NamedThing	laminin-12 complex	A laminin complex composed of alpha2, beta1 and gamma3 polypeptide chains.	tmpzr1t_l9r_go_relaxed.owl	laminin-213 complex													cellular_component											owl:Class	
GO:0003877	biolink:NamedThing	ATP adenylyltransferase activity	Catalysis of the reaction: ADP + ATP = phosphate + P(1),P(4)-bis(5'-adenosyl)tetraphosphate.	tmpzr1t_l9r_go_relaxed.owl	diadenosinetetraphosphate alpha-beta-phosphorylase activity|bis(5'-nucleosyl)-tetraphosphate phosphorylase (NDP-forming) activity|adenine triphosphate adenylyltransferase activity|diadenosine 5',5'''-P1,P4-tetraphosphate phosphorylase activity|dinucleoside oligophosphate alphabeta-phosphorylase activity|diadenosine 5',5'''-P(1),P(4)-tetraphosphate phosphorylase activity|diadenosine 5',5'''-P1,P4-tetraphosphate alphabeta-phosphorylase (ADP-forming)|AP-4-A phosphorylase activity|ADP:ATP adenylyltransferase activity|diadenosinetetraphosphate alphabeta-phosphorylase activity				RHEA:16577|EC:2.7.7.53|MetaCyc:ATP-ADENYLYLTRANSFERASE-RXN									molecular_function											owl:Class	
GO:0035496	biolink:NamedThing	lipopolysaccharide-1,5-galactosyltransferase activity	Catalysis of the reaction: UDP-galactose + lipopolysaccharide = UDP + 1,5 alpha-D-galactosyl-lipopolysaccharide.	tmpzr1t_l9r_go_relaxed.owl	UDP-D-galactose:(glucosyl)lipopolysaccharide-1,5-D-galactosyltransferase|LPS-1,5-galactosyltransferase activity							bf	2010-04-26T03:00:21Z					molecular_function											owl:Class	
GO:0046061	biolink:NamedThing	dATP catabolic process	The chemical reactions and pathways resulting in the breakdown of dATP, deoxyadenosine triphosphate (2'-deoxyadenosine 5'-triphosphate).	tmpzr1t_l9r_go_relaxed.owl	dATP catabolism|dATP breakdown|dATP degradation													biological_process											owl:Class	
GO:0006305	biolink:NamedThing	DNA alkylation	The addition of alkyl groups to many positions on all four bases of DNA. Alkylating agents can also modify the bases of incoming nucleotides in the course of DNA synthesis.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0036072	biolink:NamedThing	direct ossification	The formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone or a bony substance, that does not require the replacement of preexisting tissues.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-12-19T01:47:22Z					biological_process											owl:Class	
GO:0034820	biolink:NamedThing	4,9-DSHA hydrolase activity	Catalysis of the reaction: (3E,1Z)-4,5-9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate + H2O = (2E,4E)-2-hydroxyhexa-2,4-dienoate + 9,17-dioxo-1,2,3,4,10,19-hexanorandrostan-5-oate + H+.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r1152									molecular_function											owl:Class	
GO:0010328	biolink:NamedThing	auxin influx transmembrane transporter activity	Enables the transfer of auxin, from one side of a membrane to the other, into a cell.	tmpzr1t_l9r_go_relaxed.owl	auxin influx facilitator													molecular_function											owl:Class	
GO:0018129	biolink:NamedThing	peptidyl-oxazoline dehydrogenase activity	Catalysis of the reduction of a peptide-linked oxazoline to oxazole.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0050128	biolink:NamedThing	N-feruloylglycine deacylase activity	Catalysis of the reaction: N-feruloylglycine + H(2)O = ferulate + glycine.	tmpzr1t_l9r_go_relaxed.owl	N-feruloylglycine amidohydrolase activity|N-feruloylglycine hydrolase activity				EC:3.5.1.71|RHEA:10484|KEGG_REACTION:R03579|MetaCyc:N-FERULOYLGLYCINE-DEACYLASE-RXN									molecular_function											owl:Class	
GO:0047470	biolink:NamedThing	(1,4)-alpha-D-glucan 1-alpha-D-glucosylmutase activity	Catalysis of the reaction: 4-[(1->4)-alpha-D-glucosyl](n-1)-D-glucose = 1-alpha-D-[(1->4)-alpha-D-glucosyl](n-1)-alpha-D-glucopyranoside.	tmpzr1t_l9r_go_relaxed.owl	(1->4)-alpha-D-glucan 1-alpha-D-glucosylmutase|maltodextrin alpha-D-glucosyltransferase activity|malto-oligosyltrehalose synthase activity				EC:5.4.99.15|RHEA:13621|MetaCyc:5.4.99.15-RXN									molecular_function											owl:Class	
GO:0033704	biolink:NamedThing	3beta-hydroxy-5alpha-steroid dehydrogenase activity	Catalysis of the reaction: 3beta-hydroxy-5alpha-pregnane-20-one + NADP(+) = 5alpha-pregnane-3,20-dione + H(+) + NADPH.	tmpzr1t_l9r_go_relaxed.owl	3beta-hydroxy-5alpha-steroid:NADP+ 3-oxidoreductase activity				RHEA:18137|EC:1.1.1.278|MetaCyc:1.1.1.278-RXN|KEGG_REACTION:R07138									molecular_function											owl:Class	
GO:0009769	biolink:NamedThing	photosynthesis, light harvesting in photosystem II	After a photon of light is absorbed by one of the many chlorophyll molecules, in one of the light-harvesting complexes of an antenna on photosystem II, some of the absorbed energy is transferred to the pair of chlorophyll molecules in the reaction center.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0042565	biolink:NamedThing	RNA nuclear export complex	A complex which usually consists of three components, e.g. in Xenopus and yeast, the export receptor CRM1 (also known as exportin 1), the Ran protein and any RNA with a nuclear export sequence (NES). The complex acts to export RNA molecules with a NES from the nucleus through a nuclear pore.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0031074	biolink:NamedThing	nucleocytoplasmic transport complex	Any complex that acts to move proteins or RNAs into or out of the nucleus through nuclear pores.	tmpzr1t_l9r_go_relaxed.owl	nucleocytoplasmic shuttling complex													cellular_component											owl:Class	
GO:0102615	biolink:NamedThing	ent-cassadiene-C2-hydroxylase activity	Catalysis of the reaction: ent-cassa-12,15-diene + NADPH + O2 + H+ <=> 2alpha-hydroxy-ent-cassadiene + NADP + H2O.	tmpzr1t_l9r_go_relaxed.owl					RHEA:55484|MetaCyc:RXN-15462									molecular_function											owl:Class	
GO:0102853	biolink:NamedThing	1-18:1-2-18:1-sn-glycerol-3-phosphocholine desaturase activity	Catalysis of the reaction: 1-18:1-2-18:1-sn-glycerol-3-phosphocholine + O2 + a reduced electron acceptor <=> 1-18:2-2-18:1-phosphatidylcholine + 2 H2O + an oxidized electron acceptor.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-8320									molecular_function											owl:Class	
GO:0047708	biolink:NamedThing	biotinidase activity	Catalysis of the reaction: biotin amide + H2O = biotin + NH3.	tmpzr1t_l9r_go_relaxed.owl	biotin-amide amidohydrolase activity|amidohydrolase biotinidase activity				Reactome:R-HSA-3076905|RHEA:13081|Reactome:R-HSA-3325540|Reactome:R-HSA-4167509|EC:3.5.1.12|Reactome:R-HSA-4225086|MetaCyc:BIOTINIDASE-RXN									molecular_function											owl:Class	
GO:0021660	biolink:NamedThing	rhombomere 3 formation	The process that gives rise to rhombomere 3. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0008330	biolink:NamedThing	protein tyrosine/threonine phosphatase activity	Catalysis of the reactions: protein threonine phosphate + H2O = protein threonine + phosphate; and protein tyrosine phosphate + H2O = protein tyrosine + phosphate.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0046478	biolink:NamedThing	lactosylceramide metabolic process	The chemical reactions and pathways involving lactosylceramides, Gal-beta-(1->4)-Glc-beta-(1->1') ceramides, any compound formed by the replacement of the glycosidic C1 hydroxyl group of lactose by a ceramide group. They are the precursors of both gangliosides and globosides.	tmpzr1t_l9r_go_relaxed.owl	lactosylceramide metabolism													biological_process											owl:Class	
GO:0045175	biolink:NamedThing	basal protein localization	Any process in which a protein is transported to, or maintained in, basal regions of the cell.	tmpzr1t_l9r_go_relaxed.owl	establishment and maintenance of basal protein localization|establishment and maintenance of protein localization in basal part of cell|basal protein localisation													biological_process											owl:Class	
GO:0033745	biolink:NamedThing	L-methionine-(R)-S-oxide reductase activity	Catalysis of the reaction: L-methionine + thioredoxin disulfide + H2O = L-methionine (R)-S-oxide + thioredoxin.	tmpzr1t_l9r_go_relaxed.owl	FRMsr|free met-R-(o) reductase activity|L-methionine:thioredoxin-disulfide S-oxidoreductase [L-methionine (R)-S-oxide-forming] activity|free-methionine (R)-S-oxide reductase activity				RHEA:21260|EC:1.8.4.14|MetaCyc:1.8.4.14-RXN									molecular_function											owl:Class	
GO:0048104	biolink:NamedThing	establishment of body hair or bristle planar orientation	Orientation of hairs or sensory bristles that cover the body surface of an adult, such that they all point in a uniform direction along the plane of the epithelium from which they project.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0070549	biolink:NamedThing	siRNA-mediated gene silencing by inhibition of translation	A process of negative regulation of translation that is mediated by the association of small interfering RNAs (siRNAs) with a cognate target mRNA.	tmpzr1t_l9r_go_relaxed.owl	RNA interference, negative regulation of translation|negative regulation of translation involved in RNA interference|inhibition of translation involved in RNA interference|downregulation of translation involved in RNA interference|down regulation of translation involved in RNA interference|down-regulation of translation involved in RNA interference													biological_process											owl:Class	
GO:0008134	biolink:NamedThing	transcription factor binding	Binding to a transcription factor, a protein required to initiate or regulate transcription.	tmpzr1t_l9r_go_relaxed.owl	TF binding	https://github.com/geneontology/go-ontology/issues/19354				Note that this term should not be used for direct annotation. Please consier one of the more specific descendants, GO:0140297 ; DNA-binding transcription factor binding, GO:0140296 ; general transcription initiation factor binding or GO:0001221 ; transcription coregulator binding.								molecular_function											owl:Class	
GO:0001563	biolink:NamedThing	detection of protozoan	The series of events in which a stimulus from a protozoan is received and converted into a molecular signal.	tmpzr1t_l9r_go_relaxed.owl	detection of protozoa|detection of protozoon|perception of protozoa													biological_process											owl:Class	
GO:0102961	biolink:NamedThing	4,4'-diapophytofluene desaturase activity	Catalysis of the reaction: all-trans-4,4'-diapophytofluene + FAD + H+ = all-trans-4,4'-diapo-zeta-carotene + FADH2.	tmpzr1t_l9r_go_relaxed.owl					RHEA:31399|MetaCyc:RXN-9304									molecular_function											owl:Class	
GO:0016040	biolink:NamedThing	glutamate synthase (NADH) activity	Catalysis of the reaction: 2 L-glutamate + NAD(+) = 2-oxoglutarate + L-glutamine + H(+) + NADH.	tmpzr1t_l9r_go_relaxed.owl	L-glutamate synthase activity|NADH-dependent glutamate synthase activity|GOGAT activity|glutamate (reduced nicotinamide adenine dinucleotide) synthase|NADH-glutamate synthase activity|L-glutamate synthase (NADH)|L-glutamate:NAD+ oxidoreductase (transaminating)|NADH: GOGAT|L-glutamate synthetase activity				MetaCyc:GLUTAMATE-SYNTHASE-NADH-RXN|RHEA:13753|EC:1.4.1.14|KEGG_REACTION:R00093									molecular_function											owl:Class	
GO:0062243	biolink:NamedThing	double membrane vesicle viral factory outer membrane	The outer of the two endoplasmic reticulum-derived lipid bilayer membranes that bound a double membrane vesicle viral factory.	tmpzr1t_l9r_go_relaxed.owl	outer membrane of double membrane vesicle viral factory							dph	2020-04-20T20:47:40Z					cellular_component											owl:Class	
GO:1990268	biolink:NamedThing	response to gold nanoparticle	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gold nanoparticle stimulus.	tmpzr1t_l9r_go_relaxed.owl								sl	2014-01-10T17:37:34Z					biological_process											owl:Class	
GO:0042720	biolink:NamedThing	mitochondrial inner membrane peptidase complex	Protease complex of the mitochondrial inner membrane, consisting of at least two subunits, involved in processing of both nuclear- and mitochondrially-encoded proteins targeted to the intermembrane space.	tmpzr1t_l9r_go_relaxed.owl	IMP|mitochondrion inner membrane peptidase complex													cellular_component											owl:Class	
GO:0102762	biolink:NamedThing	eriodictyol 4'-O-methyltransferase activity	Catalysis of the reaction: eriodictyol + S-adenosyl-L-methionine  <=> H+ + hesperetin(1-) + S-adenosyl-L-homocysteine.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-7754									molecular_function											owl:Class	
GO:0031037	biolink:NamedThing	myosin II filament disassembly	The disassembly of a bipolar filament composed of myosin II molecules.	tmpzr1t_l9r_go_relaxed.owl	myosin II depolymerization													biological_process											owl:Class	
GO:1902782	biolink:NamedThing	response to decane	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a decane stimulus.	tmpzr1t_l9r_go_relaxed.owl								tt	2014-03-21T12:50:08Z					biological_process											owl:Class	
GO:0097625	biolink:NamedThing	low-affinity basic amino acid transmembrane transporter activity	Enables the transfer of basic amino acids from one side of a membrane to the other. Basic amino acids have a pH above 7. In low-affinity transport the transporter is able to bind the solute only if it is present at very high concentrations.	tmpzr1t_l9r_go_relaxed.owl	low affinity basic amino acid transmembrane transporter activity							pr	2014-08-20T14:23:18Z					molecular_function											owl:Class	
GO:1990150	biolink:NamedThing	VEGF-A complex	A homodimeric, extracellular protein complex containing two VEGF-A monomers. Binds to and activates a receptor tyrosine kinase.	tmpzr1t_l9r_go_relaxed.owl	vascular endothelial growth factor A complex							bhm	2013-07-30T13:24:41Z					cellular_component											owl:Class	
GO:1902328	biolink:NamedThing	bacterial-type DNA replication initiation	Any DNA replication initiation that is involved in bacterial-type DNA replication.	tmpzr1t_l9r_go_relaxed.owl	DNA replication initiation involved in bacterial-type DNA replication|DNA endoreduplication initiation involved in bacterial-type DNA replication|DNA re-replication initiation involved in bacterial-type DNA replication|DNA-dependent DNA replication initiation involved in bacterial-type DNA replication							jl	2013-07-25T10:48:02Z					biological_process											owl:Class	
GO:1990488	biolink:NamedThing	anaerobic cellulose catabolic process	The chemical reactions and pathways resulting in the breakdown of cellulose, a linear beta1-4 glucan of molecular mass 50-400 kDa with the pyranose units in the -4C1 conformation, in absence of oxygen.	tmpzr1t_l9r_go_relaxed.owl	anaerobic cellulose degradation							tt	2014-09-20T17:43:59Z					biological_process											owl:Class	
GO:0018834	biolink:NamedThing	dichloromethane dehalogenase activity	Catalysis of the reaction: dichloromethane + H(2)O = 2 chloride + formaldehyde + 2 H(+).	tmpzr1t_l9r_go_relaxed.owl	dichloromethane chloride-lyase (adding H2O; chloride-hydrolysing; formaldehyde-forming)|dichloromethane chloride-lyase (chloride-hydrolysing)				MetaCyc:DICHLOROMETHANE-DEHALOGENASE-RXN|UM-BBD_reactionID:r0188|EC:4.5.1.3|KEGG_REACTION:R00603|RHEA:15397									molecular_function											owl:Class	
GO:0003974	biolink:NamedThing	UDP-N-acetylglucosamine 4-epimerase activity	Catalysis of the reaction: UDP-N-acetyl-D-glucosamine = UDP-N-acetyl-D-galactosamine.	tmpzr1t_l9r_go_relaxed.owl	UDP-N-acetyl-D-glucosamine 4-epimerase activity|uridine diphosphoacetylglucosamine epimerase activity|uridine diphosphate N-acetylglucosamine-4-epimerase activity|UDP-GlcNAc 4-epimerase activity|uridine 5'-diphospho-N-acetylglucosamine-4-epimerase activity|UDP acetylglucosamine epimerase activity				EC:5.1.3.7|MetaCyc:UDP-N-ACETYLGLUCOSAMINE-4-EPIMERASE-RXN|RHEA:20517									molecular_function											owl:Class	
GO:0016223	biolink:NamedThing	beta-alanine-pyruvate transaminase activity	Catalysis of the reaction: L-alanine + 2-oxopropanoate = pyruvate + beta-alanine.	tmpzr1t_l9r_go_relaxed.owl	beta-alanine-pyruvate aminotransferase activity|beta-alanine--pyruvate aminotransferase activity|L-alanine:3-oxopropanoate aminotransferase activity|omega-amino acid--pyruvate aminotransferase activity|beta-alanine-alpha-alanine transaminase activity				EC:2.6.1.18|Reactome:R-HSA-909776|MetaCyc:2.6.1.18-RXN|RHEA:14077									molecular_function											owl:Class	
GO:0062079	biolink:NamedThing	ATG2-ATG18 complex	A protein complex essential for autophagy during nutrient deprivation, a catabolic process that sequesters undesired cellular material into autophagosomes for delivery to lysosomes for degradation. Contributes to nutrition homeostasis and damage control in eukaryotic cells. Functions at a late step of autophagosome formation for efficient completion of sequestration, probably through facilitating recruitment of ATG8-phosphatidylethanolamine (PE) to the preautophagosomal structure (PAS) and/or its protection from deconjugation by ATG4. Composed of ATG2 and ATG18 in Saccharomyces cerevisiae.	tmpzr1t_l9r_go_relaxed.owl								dph	2018-10-12T13:47:25Z					cellular_component											owl:Class	
GO:0003954	biolink:NamedThing	NADH dehydrogenase activity	Catalysis of the reaction: NADH + H+ + acceptor = NAD+ + reduced acceptor.	tmpzr1t_l9r_go_relaxed.owl	NADH diaphorase activity|diphosphopyrinase activity|NADH:acceptor oxidoreductase activity|beta-NADH dehydrogenase dinucleotide activity|NADH:(acceptor) oxidoreductase activity|NADH2 dehydrogenase activity|DPNH diaphorase activity|reduced diphosphopyridine nucleotide diaphorase activity|dihydrocodehydrogenase I dehydrogenase activity|NADH oxidoreductase activity|type I dehydrogenase activity|type 1 dehydrogenase activity|diphosphopyridine diaphorase activity|diaphorase activity|cytochrome c reductase activity|NADH hydrogenase activity|NADH:cytochrome c oxidoreductase activity|NADH-menadione oxidoreductase activity|dihydronicotinamide adenine dinucleotide dehydrogenase activity				RHEA:11356|MetaCyc:NADH-DEHYDROGENASE-RXN									molecular_function											owl:Class	
GO:0050471	biolink:NamedThing	uracilylalanine synthase activity	Catalysis of the reaction: O3-acetyl-L-serine + uracil = 3-(uracil-1-yl)-L-alanine + acetate.	tmpzr1t_l9r_go_relaxed.owl	O3-acetyl-L-serine:uracil 1-(2-amino-2-carboxyethyl)transferase activity|3-O-acetyl-L-serine:uracil 1-(2-amino-2-carboxyethyl)transferase activity|O(3)-acetyl-L-serine acetate-lyase (adding uracil) activity|isowillardiine synthase activity|Willardiine synthase activity|O3-acetyl-L-serine acetate-lyase (adding uracil)				RHEA:11496|MetaCyc:URACILYLALANINE-SYNTHASE-RXN|EC:2.5.1.53									molecular_function											owl:Class	
GO:0106153	biolink:NamedThing	phosphorylated histone binding	Binding to a histone in which a residue has been modified by phosphorylation. Histones are any of a group of water-soluble proteins found in association with the DNA of eukaroytic chromosomes.	tmpzr1t_l9r_go_relaxed.owl								hjd	2018-09-19T17:23:06Z					molecular_function											owl:Class	
GO:0072205	biolink:NamedThing	metanephric collecting duct development	The process whose specific outcome is the progression of a collecting duct in the metanephros over time, from its formation to the mature structure. The collecting duct responds to vasopressin and aldosterone to regulate water, electrolyte and acid-base balance. The collecting duct is the final common path through which urine flows before entering the ureter and then emptying into the bladder.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-03-18T11:15:37Z					biological_process											owl:Class	
GO:0051109	biolink:NamedThing	crotonobetaine-CoA ligase activity	Catalysis of the reaction: CoA + crotono-betaine + ATP = AMP + diphosphate + crotonobetainyl-CoA.	tmpzr1t_l9r_go_relaxed.owl	crotonobetaine/carnitine-CoA ligase activity|crotonobetaine-CoA synthase activity				MetaCyc:CROTCOALIG-RXN|RHEA:30079									molecular_function											owl:Class	
GO:0033307	biolink:NamedThing	phytol salvage	A process that generates phytol, (2E,7R,11R)-3,7,11,15-tetramethylhexadec-2-en-1-ol, from derivatives of it without de novo synthesis.	tmpzr1t_l9r_go_relaxed.owl	phytol salvage pathway				MetaCyc:PWY-5107									biological_process											owl:Class	
GO:1901938	biolink:NamedThing	(-)-exo-alpha-bergamotene metabolic process	The chemical reactions and pathways involving (-)-exo-alpha-bergamotene.	tmpzr1t_l9r_go_relaxed.owl	(-)-exo-alpha-bergamotene metabolism							ms	2013-02-18T14:55:23Z					biological_process											owl:Class	
GO:0033776	biolink:NamedThing	phenylacetone monooxygenase activity	Catalysis of the reaction: H(+) + NADPH + O(2) + phenylacetone = benzyl acetate + H(2)O + NADP(+).	tmpzr1t_l9r_go_relaxed.owl	phenylacetone,NADPH:oxygen oxidoreductase activity|PAMO				KEGG_REACTION:R07201|EC:1.14.13.92|RHEA:10124|MetaCyc:1.14.13.92-RXN									molecular_function											owl:Class	
GO:1903794	biolink:NamedThing	cortisol binding	Binding to cortisol.	tmpzr1t_l9r_go_relaxed.owl								mr	2015-01-14T19:02:31Z					molecular_function											owl:Class	
GO:0047584	biolink:NamedThing	4-oxalmesaconate hydratase activity	Catalysis of the reaction: 2-hydroxy-4-oxobutane-1,2,4-tricarboxylate = (1E)-4-oxobut-1-ene-1,2,4-tricarboxylate + H(2)O.	tmpzr1t_l9r_go_relaxed.owl	oxalmesaconate hydratase activity|2-hydroxy-4-oxobutane-1,2,4-tricarboxylate 2,3-hydro-lyase [(E)-4-oxobut-1-ene-1,2,4-tricarboxylate-forming]|2-hydroxy-4-oxobutane-1,2,4-tricarboxylate 2,3-hydro-lyase activity|4-carboxy-2-oxohexenedioate hydratase activity|gamma-oxalmesaconate hydratase activity|4-carboxy-2-oxobutane-1,2,4-tricarboxylate 2,3-hydro-lyase activity				RHEA:17401|EC:4.2.1.83|KEGG_REACTION:R04478|MetaCyc:RXN-2463									molecular_function											owl:Class	
GO:0008842	biolink:NamedThing	diphosphate-purine nucleoside kinase activity	Catalysis of the reaction: diphosphate + a purine nucleoside = monophosphate + a purine mononucleotide.	tmpzr1t_l9r_go_relaxed.owl	diphosphate:purine nucleoside phosphotransferase activity|diphosphate-dependent nucleoside kinase activity|pyrophosphate-purine nucleoside kinase activity|pyrophosphate-dependent nucleoside kinase activity				EC:2.7.1.143|MetaCyc:2.7.1.143-RXN									molecular_function											owl:Class	
GO:0097727	biolink:NamedThing	blepharoplast	An intracellular non-membrane-bounded organelle found in multi-ciliated sperm cells of some primitive land plants, and consisting of many radially arranged ninefold symmetric cylinders. The blepharoplast is involved in de novo formation of multiple centrioles; it enlarges and then disintegrates into many procentrioles, which elongate and ultimately nucleate cilia on the surface of the sperm cell.	tmpzr1t_l9r_go_relaxed.owl						The blepharoplast should not be confused with a basal body; rather, it acts as the precursor assembly zone for multiple basal bodies.		pr	2016-09-23T10:57:18Z					cellular_component											owl:Class	
GO:0060197	biolink:NamedThing	cloacal septation	The separation of the single opening of the digestive, urinary, and reproductive tracts, the cloaca, into multiple isolated openings during development.	tmpzr1t_l9r_go_relaxed.owl	cloaca septation													biological_process											owl:Class	
GO:0047820	biolink:NamedThing	D-glutamate cyclase activity	Catalysis of the reaction: D-glutamate = 5-oxo-D-proline + H(2)O.	tmpzr1t_l9r_go_relaxed.owl	D-glutamate hydro-lyase (cyclizing)|D-glutamate hydro-lyase (cyclizing; 5-oxo-D-proline-forming)				RHEA:22360|KEGG_REACTION:R01583|EC:4.2.1.48|MetaCyc:D-GLUTAMATE-CYCLASE-RXN									molecular_function											owl:Class	
GO:0102835	biolink:NamedThing	1-18:2-2-16:0-monogalactosyldiacylglycerol desaturase activity	Catalysis of the reaction: 1-18:2-2-16:0-monogalactosyldiacylglycerol + O2 + a reduced electron acceptor <=> 1-18:3-2-16:0-monogalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-8295|EC:1.14.19.35									molecular_function											owl:Class	
GO:0035460	biolink:NamedThing	L-ascorbate 6-phosphate lactonase activity	Catalysis of the reaction: L-ascorbate 6-phosphate + H2O = 3-keto-L-gulonate 6-phosphate.	tmpzr1t_l9r_go_relaxed.owl					RHEA:28803			bf	2010-04-16T02:05:41Z					molecular_function											owl:Class	
GO:0080180	biolink:NamedThing	2-methylguanosine metabolic process	The chemical reactions and pathways involving 2-methylguanosine.	tmpzr1t_l9r_go_relaxed.owl								dhl	2011-04-28T04:41:01Z					biological_process											owl:Class	
GO:0080030	biolink:NamedThing	methyl indole-3-acetate esterase activity	Catalysis of the reaction: methyl indole-3-acetate + H2O = indole-3-acetate + methanol + H+.	tmpzr1t_l9r_go_relaxed.owl	Methyl IAA esterase activity|MeIAA esterase activity|indole-3-Acetic acid methyl ester esterase activity				EC:3.1.1.1|MetaCyc:RXN-10711									molecular_function											owl:Class	
GO:0071283	biolink:NamedThing	cellular response to iron(III) ion	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iron(III) ion stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to iron(III)							mah	2009-12-10T03:58:00Z					biological_process											owl:Class	
GO:0004590	biolink:NamedThing	orotidine-5'-phosphate decarboxylase activity	Catalysis of the reaction: H(+) + orotidine 5'-phosphate = CO(2) + UMP.	tmpzr1t_l9r_go_relaxed.owl	ODCase activity|orotidylic acid decarboxylase activity|orotate monophosphate decarboxylase activity|orotidine-5'-phosphate carboxy-lyase activity|OMP decarboxylase activity|orotidine monophosphate decarboxylase activity|uridine 5'-monophosphate synthase activity|orotidine phosphate decarboxylase activity|orotic decarboxylase activity|OMP-DC|orotidylic decarboxylase activity|OMPdcase activity|orotidine 5'-phosphate decarboxylase activity|orotidine-5'-phosphate carboxy-lyase (UMP-forming)|UMP synthase activity|orotidine-5'-monophosphate decarboxylase activity|orotodylate decarboxylase activity|orotate decarboxylase activity				Reactome:R-HSA-73564|EC:4.1.1.23|MetaCyc:OROTPDECARB-RXN|RHEA:11596|KEGG_REACTION:R00965									molecular_function											owl:Class	
GO:0050076	biolink:NamedThing	maleate isomerase activity	Catalysis of the reaction: maleate = fumarate.	tmpzr1t_l9r_go_relaxed.owl	maleate cis-trans-isomerase activity				RHEA:13169|MetaCyc:MALEATE-ISOMERASE-RXN|EC:5.2.1.1|KEGG_REACTION:R01087									molecular_function											owl:Class	
GO:0003828	biolink:NamedThing	alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity	Catalysis of the reaction: CMP-N-acetylneuraminate + alpha-N-acetylneuraminyl-(2->3)-beta-D-galactosyl-R = CMP + alpha-N-acetylneuraminyl-(2->8)-alpha-N-acetylneuraminyl-(2->3)-beta-D-galactosyl-R.	tmpzr1t_l9r_go_relaxed.owl	CMP-NeuAc:LM1 alpha-(2->8)-sialyltranferase activity|CMP-N-acetylneuraminate:alpha-N-acetylneuraminyl-2,3-beta-D-galactoside alpha-2,8-N-acetylneuraminyltransferase activity|GD3 synthase activity|CMP-NeuAc:LM1(alpha-2,8) sialyltranferase activity|ganglioside GD3 synthase activity|SAT-2|alpha-N-acetylneuraminide alpha-2,8-sialyltransferase activity|alpha-2,8-sialyltransferase activity|cytidine monophosphoacetylneuraminate-ganglioside GM3|ganglioside GD3 synthetase sialyltransferase activity				Reactome:R-HSA-422454|MetaCyc:2.4.99.8-RXN|Reactome:R-HSA-1022133|RHEA:19313|Reactome:R-HSA-4084978|EC:2.4.99.8									molecular_function											owl:Class	
GO:0050550	biolink:NamedThing	pinene synthase activity	Catalysis of the reaction: geranyl diphosphate = pinene + diphosphate.	tmpzr1t_l9r_go_relaxed.owl	geranyldiphosphate diphosphate lyase (pinene forming)|(-)-(1S,5S)-pinene synthase activity|geranyl-diphosphate diphosphate-lyase (cyclizing, pinene-forming)|beta-geraniolene synthase activity				EC:4.2.3.14|MetaCyc:4.2.3.14-RXN									molecular_function											owl:Class	
GO:0097271	biolink:NamedThing	protein localization to bud neck	A process in which a protein is transported to, or maintained at, a location within a cellular bud neck.	tmpzr1t_l9r_go_relaxed.owl	protein localisation to bud neck|protein localization to cellular bud neck							pr	2012-03-20T03:39:20Z					biological_process											owl:Class	
GO:0018851	biolink:NamedThing	alpha-pinene-oxide decyclase activity	Catalysis of the reaction: alpha-pinene oxide = (Z)-2-methyl-5-isopropylhexa-2,5-dienal.	tmpzr1t_l9r_go_relaxed.owl	alpha-pinene-oxide lyase (decyclizing)|alpha-pinene oxide lyase activity				RHEA:16693|UM-BBD_reactionID:r0743|EC:5.5.1.10|KEGG_REACTION:R04040|MetaCyc:ALPHA-PINENE-OXIDE-DECYCLASE-RXN									molecular_function											owl:Class	
GO:0071096	biolink:NamedThing	alphaV-beta3 integrin-gelsolin complex	A protein complex that consists of an alphaV-beta3 integrin complex bound to gelsolin.	tmpzr1t_l9r_go_relaxed.owl	ITGAV-ITGB3-Gsn complex							mah	2009-11-06T04:49:31Z					cellular_component											owl:Class	
GO:0090404	biolink:NamedThing	pollen tube tip	The region at growing end of the pollen tube cell, where polarized growth occurs.	tmpzr1t_l9r_go_relaxed.owl								tb	2011-01-10T10:25:58Z					cellular_component											owl:Class	
GO:2000584	biolink:NamedThing	negative regulation of platelet-derived growth factor receptor-alpha signaling pathway	Any process that stops, prevents or reduces the frequency, rate or extent of platelet-derived growth factor receptor-alpha signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of platelet-derived growth factor receptor-alpha signalling pathway|negative regulation of alphaPDGF receptor signaling pathway|negative regulation of PDGFR-alpha signaling pathway|negative regulation of PDGF receptor-alpha signaling pathway							bf	2011-04-07T03:26:31Z					biological_process											owl:Class	
GO:0061648	biolink:NamedThing	tooth replacement	The process whose specific outcome is the replacement of an existing tooth with another tooth.	tmpzr1t_l9r_go_relaxed.owl								dph	2014-10-02T15:26:53Z					biological_process											owl:Class	
GO:2001297	biolink:NamedThing	N(omega)-methyl-L-arginine catabolic process	The chemical reactions and pathways resulting in the breakdown of N(omega)-methyl-L-arginine.	tmpzr1t_l9r_go_relaxed.owl	N(omega)-methyl-L-arginine catabolism|N(omega)-methyl-L-arginine degradation|N(omega)-methyl-L-arginine breakdown							pr	2012-02-14T03:38:21Z					biological_process											owl:Class	
GO:0045313	biolink:NamedThing	rhabdomere membrane biogenesis	A process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a rhabdomere membrane.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0047799	biolink:NamedThing	cyclopentanone monooxygenase activity	Catalysis of the reaction: cyclopentanone + H(+) + NADPH + O(2) = 5-valerolactone + H(2)O + NADP(+).	tmpzr1t_l9r_go_relaxed.owl	cyclopentanone oxygenase activity|cyclopentanone 1,2-monooxygenase activity|cyclopentanone,NADPH:oxygen oxidoreductase (5-hydroxylating, lactonizing)				MetaCyc:CYCLOPENTANONE-MONOOXYGENASE-RXN|KEGG_REACTION:R02554|EC:1.14.13.16|RHEA:15737									molecular_function											owl:Class	
GO:0010045	biolink:NamedThing	response to nickel cation	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nickel cation stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to nickel													biological_process											owl:Class	
GO:0102641	biolink:NamedThing	(R)-lactaldehyde dehydrogenase activity	Catalysis of the reaction: (R)-propane-1,2-diol + NADP <=> (R)-lactaldehyde + NADPH + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-15743									molecular_function											owl:Class	
GO:0102594	biolink:NamedThing	cyanidin 7-O-glucoside acyltransferase(acyl-glucose dependent) activity	Catalysis of the reaction: cyanidin 3,7-di-O-beta-D-glucoside betaine + 1-O-4-hydroxybenzoyl-beta-D-glucose <=> cyanidin 3-O-glucoside-7-O-(6-O-(p-hydroxybenzoyl)-glucoside) + beta-D-glucose.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-15372									molecular_function											owl:Class	
GO:0098618	biolink:NamedThing	selenomethionine-tRNA ligase activity	Catalysis of the reaction: ATP + L-selenomethionine + tRNA(Met) => AMP + diphosphate + selenomethionyl-tRNA(Met).	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-2408546									molecular_function											owl:Class	
GO:0060896	biolink:NamedThing	neural plate pattern specification	The developmental process that results in the creation of defined areas or spaces within the neural plate to which cells respond and eventually are instructed to differentiate.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-08-13T02:06:27Z					biological_process											owl:Class	
GO:0033458	biolink:NamedThing	GAC codon-amino acid adaptor activity	A triplet codon-amino acid adaptor activity that recognizes a GAC codon.	tmpzr1t_l9r_go_relaxed.owl	aspartic acid tRNA					Note that in the standard genetic code, GAC codes for aspartic acid.								molecular_function											owl:Class	
GO:0072230	biolink:NamedThing	metanephric proximal straight tubule development	The process whose specific outcome is the progression of the metanephric proximal straight tubule over time, from its formation to the mature structure. The metanephric proximal straight tubule is the part of the metanephric descending limb that extends from the metanephric proximal convoluted tubule to the metanephric descending thin tubule.	tmpzr1t_l9r_go_relaxed.owl	metanephric S3 development							mah	2010-03-18T03:38:53Z					biological_process											owl:Class	
GO:0033856	biolink:NamedThing	pyridoxine 5'-phosphate synthase activity	Catalysis of the reaction: 1-deoxy-D-xylulose 5-phosphate + 3-amino-2-oxopropyl phosphate = 2 H(2)O + H(+) + phosphate + pyridoxine 5'-phosphate.	tmpzr1t_l9r_go_relaxed.owl	1-deoxy-D-xylulose-5-phosphate:3-amino-2-oxopropyl phosphate 3-amino-2-oxopropyltransferase (phosphate-hydrolysing; cyclizing) activity|PNP synthase activity|pyridoxine 5-phosphate phospho lyase activity				RHEA:15265|EC:2.6.99.2|MetaCyc:PDXJ-RXN|KEGG_REACTION:R05838									molecular_function											owl:Class	
GO:0062011	biolink:NamedThing	mitochondrial respiratory chain complex IV pre-assembly complex	A protein complex that contributes to and regulates mitochondrial respiratory chain complex IV (COX) formation. It acts by regulating mitochondrial COX1 translation and by promoting the assembly of COX components.	tmpzr1t_l9r_go_relaxed.owl	COX1 preassemply complex|COX pre-assemply complex							dph	2018-02-28T14:50:26Z					cellular_component											owl:Class	
GO:0097296	biolink:NamedThing	activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway	Any process that initiates the activity of an inactive cysteine-type endopeptidase involved in the apoptotic signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	activation of cysteine-type endopeptidase activity involved in apoptotic signalling pathway|activation of initiator caspase activity					Components of the DISC (death-inducing signaling complex) may be annotated to this term. These include ligand-bound receptors such as FAS/CD95 (though care should be taken because FAS can also act as a non-apoptotic signal transducer), and signaling molecules such as FADD (FAS-associated protein with a death domain), cIAPs (cellular inhibitor of apoptosis proteins), c-FLIPs and caspases 8 and 10. Note that GO:0097296 should only be used to annotate gene products directly involved in the initiation or start up of an inactive cysteine-type endopeptidase activity involved in the apoptotic signaling pathway (also known as an initiator caspase). If the evidence provided is not sufficient to account for direct activation of this enzymatic activity, consider using the more generic terms GO:2001269 positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway or GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process.		pr	2012-05-02T03:19:35Z					biological_process											owl:Class	
GO:0033767	biolink:NamedThing	4-hydroxyacetophenone monooxygenase activity	Catalysis of the reaction: 4'-hydroxyacetophenone + H(+) + NADPH + O(2) = 4-hydroxyphenyl acetate + H(2)O + NADP(+).	tmpzr1t_l9r_go_relaxed.owl	HAPMO|(4-hydroxyphenyl)ethan-1-one,NADPH:oxygen oxidoreductase (ester-forming) activity				KEGG_REACTION:R06892|EC:1.14.13.84|UM-BBD_reactionID:r0756|MetaCyc:1.14.13.84-RXN|RHEA:22916									molecular_function											owl:Class	
GO:0018426	biolink:NamedThing	O3-(phosphoglycosyl-D-mannose-1-phosphoryl)-L-serine biosynthetic process	The chemical reactions and pathways resulting in the formation of O3-(phosphoglycosyl-D-mannose-1-phosphoryl)-L-serine. The polypeptide backbones of glycoproteins and mucin-like proteoglycans are extensively modified with a complex array of phosphoglycan chains that are linked to Ser/Thr-rich domains via a common Man-alpha1-PO4-Ser linkage.	tmpzr1t_l9r_go_relaxed.owl	O3-(phosphoglycosyl-D-mannose-1-phosphoryl)-L-serine anabolism|O3-(phosphoglycosyl-D-mannose-1-phosphoryl)-L-serine synthesis|O3-(phosphoglycosyl-D-mannose-1-phosphoryl)-L-serine formation|O3-(phosphoglycosyl-D-mannose-1-phosphoryl)-L-serine biosynthesis				RESID:AA0297									biological_process											owl:Class	
GO:0019324	biolink:NamedThing	L-lyxose metabolic process	The chemical reactions and pathways involving L-lyxose, the L-enantiomer of aldopentose lyxo-pentose, the C-2 epimer of xylose.	tmpzr1t_l9r_go_relaxed.owl	L-lyxose metabolism				MetaCyc:LYXMET-PWY									biological_process											owl:Class	
GO:0090638	biolink:NamedThing	phosphatidylcholine biosynthesis from phosphatidylethanolamine	The phosphatidylcholine biosynthetic process that depends on direct conversion of the phosphatidyl-base phosphatidylethanolamine to phosphatidylcholine by successive methylations.	tmpzr1t_l9r_go_relaxed.owl								tb	2015-04-23T15:56:12Z					biological_process											owl:Class	
GO:0061987	biolink:NamedThing	negative regulation of transcription from RNA polymerase II promoter by glucose	Any process involving glucose that decreases the frequency, rate or extent or transcription from an RNA polymerase II promoter.	tmpzr1t_l9r_go_relaxed.owl								dph	2018-02-15T17:48:00Z					biological_process											owl:Class	
GO:0033071	biolink:NamedThing	vancomycin metabolic process	The chemical reactions and pathways involving vancomycin, (3S,6R,7R,11R,23S,26S,30aS,36R,38aR)-44-[2-O-(3-amino-2,3,6-trideoxy-3-C-methyl-alpha-L-lyxo-hexopyranosyl)-beta-D-glucopyranosyloxy]-3-(carbamoylmethyl)-10,19-dichloro-2,3,4,5,6,7,23,25,26,36,37,38,38a-tetradecahydro-7,22,28,30,32-pentahydroxy-6-(N-methyl-D-leucyl)-2,5,24,38,39-pentaoxo-1H,22H-23,36-(epiminomethano)-8,11:18,21-dietheno-13,16:31,35-di(metheno)[1,6,9]oxadiazacyclohexadecino[4,5-m][10,2,16]benzoxadiazacyclotetracosine-26-carboxylic acid, a complex glycopeptide from Streptomyces orientalis that inhibits a specific step in the synthesis of the peptidoglycan layer in Gram-positive bacteria.	tmpzr1t_l9r_go_relaxed.owl	vancomycin metabolism													biological_process											owl:Class	
GO:0106364	biolink:NamedThing	4-hydroxy-3-all-trans-hexaprenylbenzoate oxygenase activity	4-hydroxy-3-all-trans-hexaprenylbenzoate + 2 H+ + O2 + 2 reduced [2Fe-2S]-[ferredoxin] = 3,4-dihydroxy-5-all-trans-hexaprenylbenzoate + H2O + 2 oxidized [2Fe-2S]-[ferredoxin].	tmpzr1t_l9r_go_relaxed.owl					RHEA:20361			hjd	2021-02-09T15:52:26Z					molecular_function											owl:Class	
GO:0046555	biolink:NamedThing	acetylxylan esterase activity	Catalysis of the deacetylation of xylans and xylo-oligosaccharides.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:3.1.1.72-RXN|EC:3.1.1.72									molecular_function											owl:Class	
GO:0006180	biolink:NamedThing	deoxyguanosine salvage	Any process that generates deoxyguanosine from derivatives of it, without de novo synthesis.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0062154	biolink:NamedThing	N6-mAMP deaminase activity	Catalysis of the reaction: H(+) + H2O + N6-methyl-AMP = IMP + methylamine.	tmpzr1t_l9r_go_relaxed.owl	MAPDA				RHEA:16001			dph	2019-09-20T13:16:37Z					molecular_function											owl:Class	
GO:0062049	biolink:NamedThing	protein phosphatase inhibitor complex	A protein-containing complex that inhibits protein phosphatase activity by directly binding to a protein phosphatase.	tmpzr1t_l9r_go_relaxed.owl								dph	2018-05-30T19:03:26Z					cellular_component											owl:Class	
GO:0046870	biolink:NamedThing	cadmium ion binding	Binding to a cadmium ion (Cd).	tmpzr1t_l9r_go_relaxed.owl	copper/cadmium binding|cadmium binding|Cd ion binding													molecular_function											owl:Class	
GO:0047560	biolink:NamedThing	3-dehydrosphinganine reductase activity	Catalysis of the reaction: NADP(+) + sphinganine = 3-dehydrosphinganine + H(+) + NADPH.	tmpzr1t_l9r_go_relaxed.owl	3-oxosphinganine reductase activity|D-3-oxosphinganine reductase activity|DSR activity|3-oxosphinganine:NADPH oxidoreductase activity|D-3-dehydrosphinganine reductase activity|D-3-oxosphinganine:B-NADPH oxidoreductase activity|3-ketosphinganine reductase activity|D-erythro-dihydrosphingosine:NADP+ 3-oxidoreductase activity|KTS reductase activity				EC:1.1.1.102|RHEA:22640|Reactome:R-HSA-428123|MetaCyc:3-DEHYDROSPHINGANINE-REDUCTASE-RXN|KEGG_REACTION:R02978									molecular_function											owl:Class	
GO:0009973	biolink:NamedThing	adenylyl-sulfate reductase activity	Catalysis of the reaction: AMP + sulfite + acceptor = adenylyl sulfate + reduced acceptor.	tmpzr1t_l9r_go_relaxed.owl	AMP, sulfite:acceptor oxidoreductase (adenosine-5'-phosphosulfate-forming)|AMP, sulfite:(acceptor) oxidoreductase (adenosine-5'-phosphosulfate-forming)|adenosine 5'-phosphosulfate reductase|adenosine phosphosulfate reductase activity|APS reductase activity|adenylyl-sulphate reductase activity|APS-reductase				RHEA:24240|EC:1.8.99.2|MetaCyc:ADENYLYLSULFATE-REDUCTASE-RXN									molecular_function											owl:Class	
GO:0072263	biolink:NamedThing	metanephric intraglomerular mesangial cell proliferation	The multiplication or reproduction of intraglomerular glomerular mesangium cells in the metanephros by cell division, resulting in the expansion of their population. Intraglomerular mesangial cells are specialized pericytes located among the glomerular capillaries within a renal corpuscle of a kidney. They are required for filtration, structural support and phagocytosis.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-03-30T02:27:53Z					biological_process											owl:Class	
GO:0072123	biolink:NamedThing	intraglomerular mesangial cell proliferation	The multiplication or reproduction of intraglomerular glomerular mesangium cells by cell division, resulting in the expansion of their population. Intraglomerular mesangial cells are specialized pericytes located among the glomerular capillaries within a renal corpuscle of a kidney. They are required for filtration, structural support and phagocytosis.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-02-22T01:44:29Z					biological_process											owl:Class	
GO:0034201	biolink:NamedThing	response to oleic acid	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oleic acid stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to oleate													biological_process											owl:Class	
GO:0047183	biolink:NamedThing	anthocyanin 5-aromatic acyltransferase activity	Catalysis of the reaction: anthocyanidin-3,5-diglucoside + hydroxycinnamoyl-CoA = anthocyanidin 3-glucoside-5-hydroxycinnamoylglucoside + CoA.	tmpzr1t_l9r_go_relaxed.owl	hydroxycinnamoyl-CoA:anthocyanidin 3,5-diglucoside 5-O-glucoside-6'''-O-hydroxycinnamoyltransferase activity				MetaCyc:RXN-7945|EC:2.3.1.153|RHEA:15661									molecular_function											owl:Class	
GO:0102782	biolink:NamedThing	cholestanol hydroxylase activity	Catalysis of the reaction: H+ + epidihydrocholesterin + O2 + NADPH = (22alpha)-hydroxy-cholestanol + H2O + NADP.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-7878									molecular_function											owl:Class	
GO:1903391	biolink:NamedThing	regulation of adherens junction organization	Any process that modulates the frequency, rate or extent of adherens junction organization.	tmpzr1t_l9r_go_relaxed.owl	regulation of adherens junction assembly and maintenance|regulation of adherens junction organisation							als	2014-08-27T10:08:38Z					biological_process											owl:Class	
GO:0097343	biolink:NamedThing	ripoptosome assembly	The aggregation, arrangement and bonding together of a set of components to form a ripoptosome, a protein complex whose formation can induce an extrinsic apoptotic signaling pathway or a necroptotic signaling pathway. The composition of this protein complex may depend on several factors including nature of the signal, cell type and more.	tmpzr1t_l9r_go_relaxed.owl								pr	2012-06-18T12:57:20Z					biological_process											owl:Class	
GO:0086021	biolink:NamedThing	SA node cell to atrial cardiac muscle cell communication by electrical coupling	The process that mediates signaling interactions between an SA node cardiomyocyte and an atrial cardiomyocyte by transfer of current between their adjacent cytoplasms via intercellular protein channels.	tmpzr1t_l9r_go_relaxed.owl	SA node cardiomyocyte to atrial cardiomyocyte communication by electrical coupling|sinoatrial node cardiomyocyte to atrial cardiomyocyte communication by electrical coupling|SA node cardiac muscle cell to atrial cardiac muscle cell communication by electrical coupling|SAN cardiomyocyte to atrial cardiomyocyte communication by electrical coupling|sinus node cardiomyocyte to atrial cardiomyocyte communication by electrical coupling							tb	2011-11-10T09:20:39Z					biological_process											owl:Class	
GO:0080044	biolink:NamedThing	quercetin 7-O-glucosyltransferase activity	Catalysis of the transfer of a glucosyl group from UDP-glucose to the 7-hydroxy group of a quercetin molecule.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0034866	biolink:NamedThing	2,4,4-trimethylpentanoyl-CoA dehydrogenase activity	Catalysis of the reaction: 2,4,4-trimethylpentanoyl-CoA = 2,4,4-trimethylpent-2-enoyl-CoA + 2 H+ + 2 e-.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r1276									molecular_function											owl:Class	
GO:0050113	biolink:NamedThing	inositol oxygenase activity	Catalysis of the reaction: myo-inositol + O(2) = D-glucuronate + H(2)O + H(+).	tmpzr1t_l9r_go_relaxed.owl	MOO activity|meso-inositol oxygenase activity|myo-inositol oxygenase activity|myo-inositol:oxygen oxidoreductase activity				Reactome:R-HSA-5678327|EC:1.13.99.1|MetaCyc:MYO-INOSITOL-OXYGENASE-RXN|KEGG_REACTION:R01184|RHEA:23696									molecular_function											owl:Class	
GO:0047556	biolink:NamedThing	3,4-dihydroxyphthalate decarboxylase activity	Catalysis of the reaction: 3,4-dihydroxyphthalate + H(+) = 3,4-dihydroxybenzoate + CO(2).	tmpzr1t_l9r_go_relaxed.owl	3,4-dihydroxyphthalate 2-decarboxylase activity|3,4-dihydroxyphthalate carboxy-lyase (3,4-dihydroxybenzoate-forming)|3,4-dihydroxyphthalate carboxy-lyase activity				EC:4.1.1.69|KEGG_REACTION:R01634|RHEA:18601|UM-BBD_reactionID:r1447|MetaCyc:34-DIHYDROXYPHTHALATE-DECARBOXYLASE-RXN							GO:0034913		molecular_function											owl:Class	
GO:0080064	biolink:NamedThing	4,4-dimethyl-9beta,19-cyclopropylsterol oxidation	A lipid oxidation process proceeding through a series of three successive monooxygenations of the alpha methyl group on the C4 carbon (CH3 to CH2OH to CHO to COOH) and resulting in this overall reaction: 4,4-dimethyl-9beta,19-cyclopropylsterol + 3 NADPH + 3 H+ + 3 O2 = 4-alpha-carboxy, 4-beta-methyl-9beta,19-cyclopropylsterol + 3 NADP+ + 3 H2O.	tmpzr1t_l9r_go_relaxed.owl	4,4-dimethyl-9beta,19-cyclopropylsterol-4alpha-methyl oxidase activity							dhl	2009-04-13T03:39:58Z					biological_process											owl:Class	
GO:0055129	biolink:NamedThing	L-proline biosynthetic process	The chemical reactions and pathways resulting in the formation of L-proline, an L-enantiomer of a chiral, cyclic, nonessential alpha-amino acid found in peptide linkage in proteins.	tmpzr1t_l9r_go_relaxed.owl	pyrrolidine-2-carboxylic acid biosynthetic process							jid	2009-10-22T01:59:56Z					biological_process											owl:Class	
GO:0019469	biolink:NamedThing	octopine catabolic process	The chemical reactions and pathways resulting in the breakdown of octopine (N-(1-carboxy-4-guanidinobutyl)-L-alanine), an amino acid derived opine.	tmpzr1t_l9r_go_relaxed.owl	octopine breakdown|octopine degradation|octopine catabolism				MetaCyc:OCTOPINEDEG-PWY									biological_process											owl:Class	
GO:0002287	biolink:NamedThing	alpha-beta T cell activation involved in immune response	The change in morphology and behavior of an alpha-beta T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific, leading to the initiation or perpetuation of an immune response.	tmpzr1t_l9r_go_relaxed.owl	alpha-beta T-cell activation during immune response|alpha-beta T-lymphocyte activation during immune response|alpha-beta T cell activation during immune response|alpha-beta T lymphocyte activation during immune response													biological_process											owl:Class	
GO:0031894	biolink:NamedThing	V1A vasopressin receptor binding	Binding to a V1A vasopressin receptor.	tmpzr1t_l9r_go_relaxed.owl	V1A vasopressin receptor ligand													molecular_function											owl:Class	
GO:0009510	biolink:NamedThing	plasmodesmatal desmotubule	A tightly wound cylinder of membrane that is located within the plasmodesmal pore and runs the length of the plasmodesma. The desmotubule likely provides a rigid stability to plasmodesmata and confers a fixed diameter and pore size to the plasmodesmal canal, and is linked to the endoplasmic reticulum in each of the adjacent cell.	tmpzr1t_l9r_go_relaxed.owl	desmotubule central rod											GO:0009572		cellular_component											owl:Class	
GO:0102833	biolink:NamedThing	sequoyitol galactinol:D-galactosylononitol galactosyltransferase activity	Catalysis of the reaction: 1D-5-O-methyl-myo-inositol + alpha-D-galactosyl-(1->3)-1D-myo-inositol <=> D-galactosylononitol + myo-inositol.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-8292									molecular_function											owl:Class	
GO:0036456	biolink:NamedThing	L-methionine-(S)-S-oxide reductase activity	Catalysis of the reaction: L-methionine (S)-S-oxide + thioredoxin -> L-methionine + thioredoxin disulfide + H2O.	tmpzr1t_l9r_go_relaxed.owl					RHEA:19995			bf	2013-11-27T11:07:19Z					molecular_function											owl:Class	
GO:0034565	biolink:NamedThing	1-nitro-1,2-dihydro-1,3,5-triazine hydrolase activity	Catalysis of the reaction: 1-nitro-1,2-dihydro-1,3,5-triazine + 2 H2O = 1-nitro-1,3,5-triazinane-2,4-diol.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0872|EC:3.5.99.-									molecular_function											owl:Class	
GO:0044210	biolink:NamedThing	'de novo' CTP biosynthetic process	The chemical reactions and pathways resulting in the formation of cytidine 5'-triphosphate (CTP) from simpler components.	tmpzr1t_l9r_go_relaxed.owl	'de novo' cytidine 5'-triphosphate biosynthetic process							jl	2009-10-22T03:22:34Z					biological_process											owl:Class	
GO:0071443	biolink:NamedThing	tDNA binding	Binding to DNA sequences encoding transfer RNA.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-12-16T03:47:31Z					molecular_function											owl:Class	
GO:0019371	biolink:NamedThing	cyclooxygenase pathway	The chemical reactions and pathways by which prostaglandins are formed from arachidonic acid, and in which prostaglandin-endoperoxide synthase (cyclooxygenase) catalyzes the committed step in the conversion of arachidonic acid to the prostaglandin-endoperoxides PGG2 and PGH2.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0008412	biolink:NamedThing	4-hydroxybenzoate octaprenyltransferase activity	Catalysis of the reaction: farnesylfarnesylgeranyl diphosphate + p-hydroxybenzoate = 3-octaprenyl-4-hydroxybenzoate + diphosphate.	tmpzr1t_l9r_go_relaxed.owl	PHB polyprenyl diphosphate transferase activity|para-hydroxybenzoate transferase activity|4-HB polyprenyltransferase activity|para-hydroxybenzoate:polyprenyltransferase activity|para-hydroxybenzoate-polyprenyl diphosphate transferase activity				RHEA:27782|MetaCyc:4OHBENZOATE-OCTAPRENYLTRANSFER-RXN|EC:2.5.1.39							GO:0048043|GO:0000043|GO:0048044		molecular_function											owl:Class	
GO:0140672	biolink:NamedThing	ATAC complex	A chromatin remodelling complex that regulates transcription via acetylation primarily of nucleosomal histones H3 and possibly H4. Shares the histone acetylation (HAT) module of GCN5/PCAF-ADA2-ADA3-SGF29 (or orthologs) with the related SAGA complex (GO:0000124). Contains HAT subunits GCN5 or PCAF in a mutually exclusive manner. In addition to the HAT module contains DR1/NC2B, KAT14, MBIP, WDR5, YEATS2 and ZZZ3 or orthologs. Also regulates the activity of non-histone targets and orchestrates mitotic progression by regulating Cyclin A degradation through acetylation.	tmpzr1t_l9r_go_relaxed.owl	G-ATAC complex|KAT2A-containing ATAC complex|Ada two A containing complex|Ada Two-A containing complex|ADA2A-containing complex|KAT2B-containing ATAC complex|Ada-Two-A-containing complex	https://github.com/geneontology/go-ontology/issues/21335						pg	2021-06-25T11:05:14Z					cellular_component											owl:Class	
GO:0047171	biolink:NamedThing	glucarolactone O-hydroxycinnamoyltransferase activity	Catalysis of the reaction: glucarolactone + sinapoyl-CoA = O-sinapoylglucarolactone + CoA.	tmpzr1t_l9r_go_relaxed.owl	sinapoyl-CoA:glucarolactone O-(hydroxycinnamoyl)transferase activity				EC:2.3.1.132|RHEA:14261|MetaCyc:2.3.1.132-RXN									molecular_function											owl:Class	
GO:0060890	biolink:NamedThing	limb spinous cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a limb epidermal spinous cell.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-08-13T01:31:30Z					biological_process											owl:Class	
GO:0046867	biolink:NamedThing	carotenoid transport	The directed movement of carotenoids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Carotenoids are tetraterpenoid compounds in which two units of 4 isoprenoid residues joined head-to-tail are themselves joined tail-to-tail.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0009026	biolink:NamedThing	tagaturonate reductase activity	Catalysis of the reaction: D-altronate + NAD(+) = D-tagaturonate + H(+) + NADH.	tmpzr1t_l9r_go_relaxed.owl	TagUAR|altronate oxidoreductase activity|D-tagaturonate reductase activity|altronic oxidoreductase activity|altronate dehydrogenase activity|D-altronate:NAD+ 3-oxidoreductase activity|tagaturonate dehydrogenase activity				RHEA:17813|EC:1.1.1.58|KEGG_REACTION:R02555|MetaCyc:ALTRO-OXIDOREDUCT-RXN									molecular_function											owl:Class	
GO:0042786	biolink:NamedThing	evasion of host immune response via regulation of host antigen processing and presentation	Any mechanism of active immune avoidance which works by regulating the host's antigen processing or presentation pathways, e.g. by blocking any stage in MHC class II presentation. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	active immune evasion via regulation of antigen processing and presentation|active immune evasion via modulation of antigen processing and presentation|active evasion of host immune response via regulation of host antigen processing and presentation|active evasion of host immune response via regulation of host antigen processing and presentation pathway|active immune evasion via modulation of antigen processing/presentation|active evasion of immune response of other organism via regulation of antigen processing and presentation in other organism involved in symbiotic interaction											GO:0051813		biological_process											owl:Class	
GO:0050252	biolink:NamedThing	retinol O-fatty-acyltransferase activity	Catalysis of the reaction: acyl-CoA + retinol = CoA + retinyl ester.	tmpzr1t_l9r_go_relaxed.owl	retinol fatty-acyltransferase activity|retinol acyltransferase activity|acyl-CoA:retinol O-acyltransferase activity				RHEA:11488|MetaCyc:RETINOL-O-FATTY-ACYLTRANSFERASE-RXN|Reactome:R-HSA-8848585|Reactome:R-HSA-2465919|EC:2.3.1.76									molecular_function											owl:Class	
GO:0061175	biolink:NamedThing	type II terminal bouton	Terminal inflated portion of the axon of a non-glutamatergic neuron, containing the specialized apparatus necessary to release neurotransmitters at a regulatory synapse. The axon terminus is considered to be the whole region of thickening and the terminal bouton is a specialized region of it.	tmpzr1t_l9r_go_relaxed.owl	type II terminal button							dph	2010-07-13T09:18:01Z					cellular_component											owl:Class	
GO:0047573	biolink:NamedThing	4-acetamidobutyrate deacetylase activity	Catalysis of the reaction: 4-acetamidobutanoate + H2O = acetate + 4-aminobutanoate.	tmpzr1t_l9r_go_relaxed.owl	4-acetamidobutanoate amidohydrolase activity				EC:3.5.1.63|MetaCyc:4-ACETAMIDOBUTYRATE-DEACETYLASE-RXN|RHEA:15897									molecular_function											owl:Class	
GO:1902615	biolink:NamedThing	immune response involved in response to exogenous dsRNA	Any immune response that is involved in response to exogenous dsRNA.	tmpzr1t_l9r_go_relaxed.owl	immune response involved in response to exogenous double-stranded RNA|immune response involved in response to viral dsRNA							tb	2014-01-10T01:29:25Z					biological_process											owl:Class	
GO:0018754	biolink:NamedThing	ammelide aminohydrolase activity	Catalysis of the reaction: ammelide + H2O = cyanuric acid + NH3.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-8017									molecular_function											owl:Class	
GO:0038108	biolink:NamedThing	negative regulation of appetite by leptin-mediated signaling pathway	A series of molecular signals initiated by the binding of leptin to a receptor on the surface of a cell, which reduces appetite, the desire or physical craving for food.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of appetite by leptin-mediated signalling pathway|inhibition of appetite by leptin signaling|reduction of appetite by leptin-mediated signaling|suppression of appetite by leptin-mediated signaling pathway							bf	2012-03-09T11:14:36Z					biological_process											owl:Class	
GO:0033762	biolink:NamedThing	response to glucagon	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucagon stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to glucagon stimulus													biological_process											owl:Class	
GO:0030381	biolink:NamedThing	chorion-containing eggshell pattern formation	The regionalization process that gives rise to the structural pattern of a chorion-containing eggshell such as those found in insects.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0086098	biolink:NamedThing	angiotensin-activated signaling pathway involved in heart process	An angiotensin receptor signaling pathway which contributes to a circulatory system process carried out by the heart.	tmpzr1t_l9r_go_relaxed.owl	angiotensin receptor signalling pathway involved in heart process|angiotensin-mediated signaling pathway involved in heart process|angiotensin receptor signaling pathway involved in heart process							bf						biological_process											owl:Class	
GO:0019237	biolink:NamedThing	centromeric DNA binding	Binding to a centromere, a region of chromosome where the spindle fibers attach during mitosis and meiosis.	tmpzr1t_l9r_go_relaxed.owl	centromere binding													molecular_function											owl:Class	
GO:0006436	biolink:NamedThing	tryptophanyl-tRNA aminoacylation	The process of coupling tryptophan to tryptophanyl-tRNA, catalyzed by tryptophanyl-tRNA synthetase. The tryptophanyl-tRNA synthetase is a  class-I synthetase. The activated amino acid is transferred to the 2'-OH group of a tryptophan-accetping tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0004042	biolink:NamedThing	acetyl-CoA:L-glutamate N-acetyltransferase activity	Catalysis of the reaction: L-glutamate + acetyl-CoA = N-acetyl-L-glutamate + CoA + H(+).	tmpzr1t_l9r_go_relaxed.owl	amino acid acetyltransferase activity|N-acetylglutamate synthase activity|acetylglutamate acetylglutamate synthetase activity|amino-acid N-acetyltransferase activity|AGAS				Reactome:R-HSA-70542|KEGG_REACTION:R00259|EC:2.3.1.1|MetaCyc:N-ACETYLTRANSFER-RXN|RHEA:24292									molecular_function											owl:Class	
GO:0047461	biolink:NamedThing	(+)-delta-cadinene synthase activity	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = diphosphate + (+)-delta-cadinene.	tmpzr1t_l9r_go_relaxed.owl	2-trans,6-trans-farnesyl-diphosphate diphosphate-lyase (cyclizing, (+)-delta-cadinene-forming)|D-cadinene synthase activity				EC:4.2.3.13|MetaCyc:4.6.1.11-RXN|RHEA:19525									molecular_function											owl:Class	
GO:0051421	biolink:NamedThing	regulation of endo-1,4-beta-xylanase activity	Any process that modulates the frequency, rate or extent of endo-(1->4)-beta-xylanase activity, the catalysis of the endohydrolysis of (1->4)-beta-D-xylosidic linkages in xylans.	tmpzr1t_l9r_go_relaxed.owl	endo-1,4-beta-xylanase regulator|xylanase regulator													biological_process											owl:Class	
GO:0072150	biolink:NamedThing	juxtaglomerulus cell fate commitment	The process in which the developmental fate of a cell becomes restricted such that it will develop into a juxtaglomerulus cell.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-02-24T02:09:49Z					biological_process											owl:Class	
GO:0018644	biolink:NamedThing	toluene 2-monooxygenase activity	Catalysis of the reaction: toluene + 1/2 O2 = 2-hydroxytoluene.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_enzymeID:e0222|EC:1.14.13.243|RHEA:20349|MetaCyc:TOLUENE-2-MONOOXYGENASE-RXN									molecular_function											owl:Class	
GO:0033956	biolink:NamedThing	beta-apiosyl-beta-glucosidase activity	Catalysis of the reaction: 7-[beta-D-apiofuranosyl-(1->6)-beta-D-glucopyranosyloxy]isoflavonoid + H2O = a 7-hydroxyisoflavonoid + beta-D-apiofuranosyl-(1->6)-D-glucose.	tmpzr1t_l9r_go_relaxed.owl	isoflavonoid-7-O-beta[D-apiosyl-(1->6)-beta-D-glucoside] disaccharidase activity|furcatin hydrolase activity|7-[beta-D-apiofuranosyl-(1->6)-beta-D-glucopyranosyloxy]isoflavonoid beta-D-apiofuranosyl-(1->6)-D-glucohydrolase activity|isoflavonoid 7-O-beta-apiosyl-glucoside beta-glucosidase activity				MetaCyc:3.2.1.161-RXN|EC:3.2.1.161|MetaCyc:RXN-9156|RHEA:21488									molecular_function											owl:Class	
GO:0015050	biolink:NamedThing	methane monooxygenase complex	A protein complex that possesses methane monooxygenase activity; dimeric and trimeric complexes have been characterized.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0047239	biolink:NamedThing	hydroxymandelonitrile glucosyltransferase activity	Catalysis of the reaction: 4-hydroxymandelonitrile + UDP-D-glucose = H(+) + taxiphyllin + UDP.	tmpzr1t_l9r_go_relaxed.owl	cyanohydrin glucosyltransferase activity|UDP-glucose:4-hydroxymandelonitrile glucosyltransferase activity|UDPglucose:4-hydroxymandelonitrile glucosyltransferase activity				EC:2.4.1.178|RHEA:15961|KEGG_REACTION:R02709|MetaCyc:2.4.1.178-RXN									molecular_function											owl:Class	
GO:0060758	biolink:NamedThing	foraging behavior by probing substrate	Foraging behavior in which an anatomical part of the organism is inserted into the substrate to locate food.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-06-22T02:53:09Z					biological_process											owl:Class	
GO:0102253	biolink:NamedThing	neoagarobiose 1,3-alpha-3,6-anhydro-L-galactosidase activity	Catalysis of the reaction: neoagarobiose + H2O <=> 3,6-anhydro-alpha-L-galactopyranose + beta-D-galactoside.	tmpzr1t_l9r_go_relaxed.owl					EC:3.2.1.159|MetaCyc:RXN-12426									molecular_function											owl:Class	
GO:0033475	biolink:NamedThing	indoleacetic acid amide conjugate biosynthetic process	The chemical reactions and pathways resulting in the formation of an indole-3-acetic acid amide conjugate, a form of indoleacetic acid covalently bound to an amino acid or polypeptide through an amide bond.	tmpzr1t_l9r_go_relaxed.owl	indoleacetic acid amide conjugate anabolism|indoleacetic acid amide conjugate synthesis|indoleacetic acid amide conjugate formation|indoleacetic acid amide conjugate biosynthesis|indole acetic acid amide conjugate biosynthesis|indole acetic acid amide conjugate biosynthetic process|IAA amide conjugate biosynthetic process				MetaCyc:PWY-1782									biological_process											owl:Class	
GO:0085016	biolink:NamedThing	dormancy exit of symbiont in host	Exit from dormant state, also known as resuscitation, of the symbiont within the host organism.	tmpzr1t_l9r_go_relaxed.owl	resuscitation of symbiont							jl	2010-05-19T03:23:07Z					biological_process											owl:Class	
GO:0031704	biolink:NamedThing	apelin receptor binding	Binding to an apelin receptor.	tmpzr1t_l9r_go_relaxed.owl	apelin receptor ligand|APJ receptor binding											GO:0042569		molecular_function											owl:Class	
GO:0015066	biolink:NamedThing	alpha-amylase inhibitor activity	Binds to and stops, prevents or reduces the activity of alpha-amylase.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1904392	biolink:NamedThing	cellular response to ciliary neurotrophic factor	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ciliary neurotrophic factor stimulus.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-06-23T19:13:10Z					biological_process											owl:Class	
GO:0009455	biolink:NamedThing	redox taxis	The directed movement of a motile cell or organism in response to redox potential.	tmpzr1t_l9r_go_relaxed.owl	taxis in response to redox potential|taxis in response to redox stimulus|redoxtaxis													biological_process											owl:Class	
GO:0010078	biolink:NamedThing	maintenance of root meristem identity	The process in which an organism retains a population of root meristem cells, preventing the commitment of all stem cell progeny to a differentiated cell fate.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0001742	biolink:NamedThing	oenocyte differentiation	The process in which a relatively unspecialized cell acquires the specialized features of an oenocyte. Oenocytes are large secretory cells found in clusters underlying the epidermis of larval abdominal segments.	tmpzr1t_l9r_go_relaxed.owl	oenocyte cell differentiation													biological_process											owl:Class	
GO:0042409	biolink:NamedThing	caffeoyl-CoA O-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + caffeoyl-CoA = S-adenosyl-L-homocysteine + feruloyl-CoA.	tmpzr1t_l9r_go_relaxed.owl	caffeoyl-CoA 3-O-methyltransferase activity|S-adenosyl-L-methionine:caffeoyl-CoA 3-O-methyltransferase activity|caffeoyl coenzyme A methyltransferase activity|trans-caffeoyl-CoA 3-O-methyltransferase activity				RHEA:16925|MetaCyc:CAFFEOYL-COA-O-METHYLTRANSFERASE-RXN|EC:2.1.1.104									molecular_function											owl:Class	
GO:0071544	biolink:NamedThing	diphosphoinositol polyphosphate catabolic process	The chemical reactions and pathways resulting in the breakdown of a diphosphoinositol polyphosphate, 1,2,3,4,5,6-cyclohexanehexol with one or more diphosphate groups and multiple monophosphate groups attached.	tmpzr1t_l9r_go_relaxed.owl	diphosphoinositol polyphosphate breakdown|diphosphoinositol polyphosphate degradation|diphosphoinositol polyphosphate catabolism							mah	2010-01-12T05:07:10Z					biological_process											owl:Class	
GO:0071543	biolink:NamedThing	diphosphoinositol polyphosphate metabolic process	The chemical reactions and pathways involving a diphosphoinositol polyphosphate, 1,2,3,4,5,6-cyclohexanehexol with one or more diphosphate groups and multiple monophosphate groups attached.	tmpzr1t_l9r_go_relaxed.owl	diphosphoinositol polyphosphate metabolism							mah	2010-01-12T05:04:00Z					biological_process											owl:Class	
GO:0004621	biolink:NamedThing	glycosylphosphatidylinositol phospholipase D activity	Catalysis of the reaction: glycoprotein phosphatidylinositol + H2O = phosphatidate + glycoprotein inositol.	tmpzr1t_l9r_go_relaxed.owl	phosphatidylinositol-specific phospholipase D activity|phosphatidylinositol-glycan-specific phospholipase D activity|glycoprotein phospholipase D activity|GPI-PLD activity|phosphatidylinositol phospholipase D activity|glycoprotein-phosphatidylinositol phosphatidohydrolase activity				MetaCyc:GLYCOPROTEIN-PHOSPHOLIPASE-D-RXN|RHEA:10832|Reactome:R-HSA-8940388|EC:3.1.4.50									molecular_function											owl:Class	
GO:0009652	biolink:NamedThing	thigmotropism	The movement of an organism, or part of an organism, such as leaves or tendrils, in response to a touch stimulus, usually toward or away from it.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Thigmotropism									biological_process											owl:Class	
GO:0102747	biolink:NamedThing	chlorophyllide-a:geranyl-geranyl diphosphate geranyl-geranyl transferase activity	Catalysis of the reaction: H+ + chlorophyllide a(1-) + 2-trans,6-trans,10-trans-geranylgeranyl diphosphate(3-) <=> geranylgeranyl-chlorophyll a + diphosphoric acid.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-7663									molecular_function											owl:Class	
GO:0098519	biolink:NamedThing	nucleotide phosphatase activity, acting on free nucleotides	Catalysis of the reaction: nucleotide + H2O = nucleotide + phosphate.	tmpzr1t_l9r_go_relaxed.owl	nucleotide phosphatase activity					To be used for NTP->NDP or NDP -> NMP. For nucleotide -> nucleoside (all phosphates removed) use nucleotidase.		dos	2013-09-26T11:04:45Z					molecular_function											owl:Class	
GO:0031885	biolink:NamedThing	type 1 member 2 taste receptor binding	Binding to a type 1 member 2 taste receptor.	tmpzr1t_l9r_go_relaxed.owl	type 1 member 2 taste receptor ligand													molecular_function											owl:Class	
GO:0018715	biolink:NamedThing	9-phenanthrol UDP-glucuronosyltransferase activity	Catalysis of the reaction: 9-phenanthrol + UDP-glucuronate = 9-phenanthryl-beta-D-glucuronide + UDP.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0567									molecular_function											owl:Class	
GO:0061561	biolink:NamedThing	trigeminal ganglion formation	The process that gives rise to the trigeminal ganglion. This process pertains to the initial formation of a structure from unspecified parts.	tmpzr1t_l9r_go_relaxed.owl	trigeminal ganglia formation							dph	2013-07-10T09:08:13Z					biological_process											owl:Class	
GO:0061560	biolink:NamedThing	cranial ganglion formation	The process that gives rise to a cranial ganglion. This process pertains to the initial formation of a structure from unspecified parts.	tmpzr1t_l9r_go_relaxed.owl	cranial ganglia formation							dph	2013-07-10T09:07:27Z					biological_process											owl:Class	
GO:0070780	biolink:NamedThing	dihydrosphingosine-1-phosphate phosphatase activity	Catalysis of the reaction: dihydrosphingosine 1-phosphate + H2O = dihydrosphingosine + phosphate.	tmpzr1t_l9r_go_relaxed.owl	dihydrosphingosine-1-phosphate phosphohydrolase activity|sphinganine-1-phosphate phosphatase activity				RHEA:27514|Reactome:R-HSA-428664|MetaCyc:RXN3DJ-25			mah	2009-07-02T02:13:49Z					molecular_function											owl:Class	
GO:0047739	biolink:NamedThing	cephalosporin-C deacetylase activity	Catalysis of the reaction: cephalosporin C + H(2)O = acetate + deacetylcephalosporin C + H(+).	tmpzr1t_l9r_go_relaxed.owl	cephalosporin C deacetylase activity|cephalosporin C acetylase activity|cephalosporin-C acetylhydrolase activity|cephalosporin C acetyl-hydrolase activity|cephalosporin C acetylesterase activity|cephalosporin C acetyl-esterase activity|cephalosporin acetylesterase activity				RHEA:22596|MetaCyc:CEPHALOSPORIN-C-DEACETYLASE-RXN|EC:3.1.1.41|KEGG_REACTION:R03062									molecular_function											owl:Class	
GO:0102537	biolink:NamedThing	ecdysone-phosphate phosphatase activity	Catalysis of the reaction: ecdysone 22-phosphate + H2O <=> ecdysone + hydrogenphosphate.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-14766									molecular_function											owl:Class	
GO:0034723	biolink:NamedThing	DNA replication-dependent chromatin organization	The formation or destruction of chromatin structures on newly replicated DNA, coupled to strand elongation.	tmpzr1t_l9r_go_relaxed.owl	DNA replication-dependent nucleosome organization|DNA replication-dependent nucleosome organisation	https://github.com/geneontology/go-ontology/issues/22130												biological_process											owl:Class	
GO:0071329	biolink:NamedThing	cellular response to sucrose stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sucrose stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-12-10T05:31:22Z					biological_process											owl:Class	
GO:1905474	biolink:NamedThing	canonical Wnt signaling pathway involved in stem cell proliferation	Any canonical Wnt signaling pathway that is involved in stem cell proliferation.	tmpzr1t_l9r_go_relaxed.owl	Wnt receptor signaling pathway via beta-catenin involved in stem cell proliferation|Wnt receptor signaling pathway through beta-catenin involved in stem cell proliferation|canonical Wnt-activated signaling pathway involved in stem cell proliferation|canonical Wnt receptor signaling pathway involved in stem cell proliferation|frizzled-1 receptor signaling pathway involved in stem cell proliferation|Wnt receptor signalling pathway through beta-catenin involved in stem cell proliferation							bc	2016-09-21T15:59:53Z					biological_process											owl:Class	
GO:0044529	biolink:NamedThing	regulation of mitochondrial rRNA stability	Any process that modulates the propensity of mitochondrial rRNA molecules to degradation. Includes processes that both stabilize and destabilize mitochondrial rRNAs.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-03-15T03:22:19Z					biological_process											owl:Class	
GO:0098770	biolink:NamedThing	FBXO family protein binding	Binding to a member of the FBXO protein family. Members of this family have an F-box protein motif of approximately 50 amino acids that functions as a site of protein-protein interaction.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0110134	biolink:NamedThing	meiotic drive	A biological process that results in the unequal transmission of alleles, haplotypes, or chromosomes from a parental genome to gametes. In the absence of meiotic drive, the two copies of each gene or chromosome in a diploid organism are transmitted to offspring with equal probability, whereas meiotic drive results in overrepresentation of the driving allele among the surviving products of meiosis.	tmpzr1t_l9r_go_relaxed.owl								kmv	2019-01-02T17:37:09Z					biological_process											owl:Class	
GO:0009940	biolink:NamedThing	amino-terminal vacuolar sorting propeptide binding	Binding to an amino terminal propeptide, which functions as a sorting signal to sort away the soluble vacuolar protein from Golgi to lytic vacuole via clathrin-coated vesicles.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0010209	biolink:NamedThing	vacuolar sorting signal binding	Binding to a vacuolar sorting signal, a specific peptide sequence that acts as a signal to localize the protein within the vacuole.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0098727	biolink:NamedThing	maintenance of cell number	Any process by which the numbers of cells of a particular type or in a tissue are maintained.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0102059	biolink:NamedThing	2-cis,6-cis-farnesyl pyrophosphate synthase activity	Catalysis of the reaction: dimethylallyl diphosphate + 2 isopentenyl diphosphate <=> 2 diphosphate + (2Z,6Z)-farnesyl diphosphate.	tmpzr1t_l9r_go_relaxed.owl	neryl-diphosphate:isopentenyl-diphosphate cistransferase activity				EC:2.5.1.92|MetaCyc:RXN-11973|MetaCyc:RXN-10481|RHEA:27810							GO:0102192		molecular_function											owl:Class	
GO:0098629	biolink:NamedThing	trans-Golgi network membrane organization	A process which results in the assembly, arrangement of constituent parts, or disassembly of a trans-Golgi network membrane.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0008688	biolink:NamedThing	3-(3-hydroxyphenyl)propionate hydroxylase activity	Catalysis of the reaction: 3-(3-hydroxyphenyl)propionate + NADH + oxygen + H+ = 3-(2,3-dihydroxyphenyl)propionate + NAD+ + H2O.	tmpzr1t_l9r_go_relaxed.owl					EC:1.14.13.127|RHEA:24785|MetaCyc:MHPHYDROXY-RXN|KEGG_REACTION:R06786									molecular_function											owl:Class	
GO:0035197	biolink:NamedThing	siRNA binding	Binding to a small interfering RNA, a 21-23 nucleotide RNA that is processed from double stranded RNA (dsRNA) by an RNAse enzyme.	tmpzr1t_l9r_go_relaxed.owl	small interfering RNA binding													molecular_function											owl:Class	
GO:0097125	biolink:NamedThing	cyclin B1-CDK1 complex	A protein complex consisting of cyclin B1 and cyclin-dependent kinase 1 (CDK1). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner.	tmpzr1t_l9r_go_relaxed.owl								pr	2011-08-01T01:45:15Z					cellular_component											owl:Class	
GO:0018187	biolink:NamedThing	molybdenum incorporation via L-cysteinyl molybdopterin guanine dinucleotide	The incorporation of molybdenum into a protein by L-cysteinyl molybdopterin guanine dinucleotide.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0281									biological_process											owl:Class	
GO:0062064	biolink:NamedThing	box C/D snoRNP complex binding	Binding to a box C/D snoRNP complex.	tmpzr1t_l9r_go_relaxed.owl								dph	2018-08-31T14:01:03Z					molecular_function											owl:Class	
GO:0002268	biolink:NamedThing	follicular dendritic cell differentiation	The process in which a relatively unspecialized precursor cell acquires the specialized features of a follicular dendritic cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0047788	biolink:NamedThing	2-coumarate reductase activity	Catalysis of the reaction: 3-(2-hydroxyphenyl)propanoate + NAD(+) = trans-2-coumarate + H(+) + NADH.	tmpzr1t_l9r_go_relaxed.owl	3-(2-hydroxyphenyl)propanoate:NAD+ oxidoreductase activity|coumarate reductase activity|melilotate dehydrogenase activity				EC:1.3.1.11|MetaCyc:COUMARATE-REDUCTASE-RXN|RHEA:21444|KEGG_REACTION:R03709									molecular_function											owl:Class	
GO:0033309	biolink:NamedThing	SBF transcription complex	A protein complex that binds to the Swi4/6 cell cycle box (SCB) promoter element, consensus sequence CRCGAAA, and activates transcription during the G1/S transition of the cell cycle. In Saccharomyces, the complex contains a heterodimer of the DNA binding protein Swi4p and the activator Swi6p, and is associated with additional proteins known as Whi5p and Msa1p.	tmpzr1t_l9r_go_relaxed.owl	SBF complex													cellular_component											owl:Class	
GO:0002748	biolink:NamedThing	antigen processing and presentation initiated by pattern recognition receptor mediated uptake of antigen	Antigen processing and presentation which is initiated by uptake of antigen bound to a cell surface pattern recognition receptor (PRR).	tmpzr1t_l9r_go_relaxed.owl	antigen processing and presentation initiated by PRR mediated uptake of antigen|antigen processing and presentation initiated by PAMP receptor mediated uptake of antigen													biological_process											owl:Class	
GO:0031730	biolink:NamedThing	CCR5 chemokine receptor binding	Binding to a CCR5 chemokine receptor.	tmpzr1t_l9r_go_relaxed.owl	CCR5 chemokine receptor ligand													molecular_function											owl:Class	
GO:0009390	biolink:NamedThing	dimethyl sulfoxide reductase complex	An enzyme complex that catalyzes the formation of dimethyl sulfide from dimethyl sulfoxide.	tmpzr1t_l9r_go_relaxed.owl	dimethyl sulphoxide reductase complex													cellular_component											owl:Class	
GO:0032935	biolink:NamedThing	sterol sensor activity	Binding to and responding, e.g. by conformational change, to changes in the cellular level of a sterol.	tmpzr1t_l9r_go_relaxed.owl	sterol-sensing domain													molecular_function											owl:Class	
GO:0140206	biolink:NamedThing	dipeptide import across plasma membrane	The directed movement of a dipeptide from outside of a cell, across the plasma membrane and into the cytosol.	tmpzr1t_l9r_go_relaxed.owl								pg	2018-02-22T15:49:19Z					biological_process											owl:Class	
GO:0047817	biolink:NamedThing	D-arginase activity	Catalysis of the reaction: D-arginine + H(2)O = D-ornithine + urea.	tmpzr1t_l9r_go_relaxed.owl	D-arginine amidinohydrolase activity				EC:3.5.3.10|RHEA:12901|MetaCyc:D-ARGINASE-RXN|KEGG_REACTION:R02458									molecular_function											owl:Class	
GO:0000048	biolink:NamedThing	peptidyltransferase activity	Catalysis of the reaction: peptidyl-tRNA(1) + aminoacyl-tRNA(2) = tRNA(1) + peptidylaminoacyl-tRNA(2).	tmpzr1t_l9r_go_relaxed.owl	peptidyl-tRNA:aminoacyl-tRNA N-peptidyltransferase activity	https://github.com/geneontology/go-ontology/issues/22192			Reactome:R-HSA-156912|EC:2.3.2.12|MetaCyc:PEPTIDYLTRANSFERASE-RXN									molecular_function											owl:Class	
GO:0070123	biolink:NamedThing	transforming growth factor beta receptor activity, type III	Combining with transforming growth factor beta to initiate a change in cell activity; facilitates ligand binding to type I and type II TGF-beta receptors.	tmpzr1t_l9r_go_relaxed.owl	betaglycan|type III transforming growth factor beta receptor activity|transforming growth factor beta ligand binding to type III receptor|type III TGFbeta receptor activity|type III TGF-beta receptor activity|endoglin													molecular_function											owl:Class	
GO:0008266	biolink:NamedThing	poly(U) RNA binding	Binding to a sequence of uracil residues in an RNA molecule.	tmpzr1t_l9r_go_relaxed.owl	poly(U) binding													molecular_function											owl:Class	
GO:0090122	biolink:NamedThing	cholesterol ester hydrolysis involved in cholesterol transport	The cholesterol metabolic process in which cholesterol esters are hydrolyzed into free fatty acids and cholesterol in the lysosome that contributes to intracellular cholesterol transport.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-12-07T01:06:54Z					biological_process											owl:Class	
GO:0120146	biolink:NamedThing	sulfatide binding	Binding to sulfatide, also known as 3-O-sulfogalactosylceramide, SM4, or sulfated galactocerebroside. Sulfatide is a class of sulfoglycolipid, which are glycolipids that contain a sulfate group.	tmpzr1t_l9r_go_relaxed.owl	SM4 binding|3-O-sulfogalactosylceramide binding|sulfated galactocerebroside binding							krc	2018-03-30T20:44:03Z					molecular_function											owl:Class	
GO:0005953	biolink:NamedThing	CAAX-protein geranylgeranyltransferase complex	A heterodimeric enzyme, composed of an alpha and a beta subunit. Participates in the post-translational C-terminal modification of several small GTPases, allowing their targeting to the membrane.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0050640	biolink:NamedThing	isopenicillin-N N-acyltransferase activity	Catalysis of the reaction: phenylacetyl-CoA + isopenicillin N + H2O = CoA + penicillin G + L-2-aminohexanedioate.	tmpzr1t_l9r_go_relaxed.owl	acyl-coenzyme A:6-aminopenicillanic-acid-acyltransferase activity|acyl-CoA:isopenicillin N N-acyltransferase activity|acyl-coenzyme A:isopenicillin N acyltransferase activity|isopenicillin N:acyl-CoA acyltransferase activity|isopenicillin-N acyltransferase activity				MetaCyc:2.3.1.164-RXN|EC:2.3.1.164|RHEA:20720							GO:0042319|GO:0045440		molecular_function											owl:Class	
GO:0006178	biolink:NamedThing	guanine salvage	Any process that generates guanine, 2-amino-6-hydroxypurine, from derivatives of it without de novo synthesis.	tmpzr1t_l9r_go_relaxed.owl	guanine, xanthine and their nucleoside salvage													biological_process											owl:Class	
GO:0018528	biolink:NamedThing	iminodiacetate dehydrogenase activity	Catalysis of the reaction: iminodiacetate + OH- = H+ + 2 e- + glyoxylate + glycine.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0589									molecular_function											owl:Class	
GO:0047794	biolink:NamedThing	cyclohexadienyl dehydrogenase activity	Catalysis of the reaction: L-arogenate + NAD+ = L-tyrosine + NADH + CO2.	tmpzr1t_l9r_go_relaxed.owl	pretyrosine dehydrogenase activity|L-arogenate:NAD(+) oxidoreductase activity|L-arogenate:NAD+ oxidoreductase activity|arogenate dehydrogenase activity|L-arogenate:NAD+ oxidoreductase (decarboxylating)|arogenic dehydrogenase activity				EC:1.3.1.43|MetaCyc:CYCLOHEXADIENYL-DEHYDROGENASE-RXN|RHEA:12256									molecular_function											owl:Class	
GO:0050301	biolink:NamedThing	streptomycin-6-phosphatase activity	Catalysis of the reaction: H(2)O + streptomycin 6-phosphate = phosphate + streptomycin.	tmpzr1t_l9r_go_relaxed.owl	streptomycin 6-phosphate phosphohydrolase activity|streptomycin-6-phosphate phosphohydrolase activity|streptomycin 6-phosphate phosphatase activity|streptomycin-6-P phosphohydrolase activity				KEGG_REACTION:R02228|RHEA:10688|MetaCyc:STREPTOMYCIN-6-PHOSPHATASE-RXN|EC:3.1.3.39									molecular_function											owl:Class	
GO:0102352	biolink:NamedThing	phosphatidate kinase activity	Catalysis of the reaction: ATP + a 1,2-diacyl-sn-glycerol 3-phosphate = ADP + a 1,2-diacyl-sn-glycerol 3-diphosphate.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-13336									molecular_function											owl:Class	
GO:0015830	biolink:NamedThing	diaminopimelate transport	The directed movement of diaminopimelate, the anion of 2,6-diaminoheptanedioic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0022810	biolink:NamedThing	membrane potential driven uniporter activity	Enables the active transport of a solute across a membrane by a mechanism involving conformational change, where energy for active transport is derived from membrane potential if the solute is charged.	tmpzr1t_l9r_go_relaxed.owl	porter													molecular_function											owl:Class	
GO:0080034	biolink:NamedThing	host response to induction by symbiont of tumor, nodule or growth in host	Any process that results in a change in the state or activity of a host cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the formation of an abnormal mass of cells in the host organism, induced by a symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0046088	biolink:NamedThing	cytidine biosynthetic process	The chemical reactions and pathways resulting in the formation of cytidine, cytosine riboside, a widely distributed nucleoside.	tmpzr1t_l9r_go_relaxed.owl	cytidine anabolism|cytidine biosynthesis|cytidine synthesis|cytidine formation													biological_process											owl:Class	
GO:0030169	biolink:NamedThing	low-density lipoprotein particle binding	Binding to a low-density lipoprotein particle, a lipoprotein particle that is rich in cholesterol esters and low in triglycerides, is typically composed of APOB100 and APOE, and has a density of 1.02-1.06 g/ml and a diameter of between 20-25 nm.	tmpzr1t_l9r_go_relaxed.owl	LDL binding													molecular_function											owl:Class	
GO:0097370	biolink:NamedThing	protein O-GlcNAcylation via threonine	The glycosylation of a protein by addition of N-acetylglucosamine via the O3 atom of peptidyl-threonine, forming O3-N-acetylglucosamine-L-threonine.	tmpzr1t_l9r_go_relaxed.owl								pr	2012-08-06T16:57:37Z					biological_process											owl:Class	
GO:0052156	biolink:NamedThing	modulation by symbiont of host T-cell mediated immune response	Any process in which an organism modulates the frequency, rate or extent of the T-cell mediated immune response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	modulation by organism of T-cell mediated immune response of other organism involved in symbiotic interaction											GO:0052295		biological_process											owl:Class	
GO:0008437	biolink:NamedThing	thyrotropin-releasing hormone activity	The action characteristic of thyrotropin-releasing hormone (TRH), a hormone released by the mammalian hypothalamus into the hypophyseal-portal circulation in response to neural and/or chemical stimuli. Upon receptor binding, TRH increases the secretion of thyroid-stimulating hormone by the anterior pituitary.	tmpzr1t_l9r_go_relaxed.owl	thyrotropin releasing hormone activity|TRH activity													molecular_function											owl:Class	
GO:0102372	biolink:NamedThing	alpha-amyrin 28-monooxygenase activity	Catalysis of the reaction: alpha-amyrin + NADPH(4-) + O2 + H+ <=> uvaol + NADP(3-) + H2O.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-13500									molecular_function											owl:Class	
GO:0102539	biolink:NamedThing	UDP-N-acetyl-alpha-D-fucosamine dehydrogenase activity	Catalysis of the reaction: UDP-N-acetyl-alpha-D-fucosamine + NAD(P) = UDP-2-acetamido-4-dehydro-2,6-dideoxy-beta-D-glucose + H+ + NAD(P)H.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-14769									molecular_function											owl:Class	
GO:0120312	biolink:NamedThing	ciliary basal body segregation	The process in which the duplicated basal bodies migrate in pairs to the mitotic poles of the nucleus and results in equal distribution in the daughter cells. Ciliary basal body segregation ensures inheritance of the duplicated mitochondrial DNA to the two daughter cells in the Trypanosoma parasites.	tmpzr1t_l9r_go_relaxed.owl	microtubule basal body segregation|ciliary basal body separation|microtubule basal body separation							krc	2021-03-27T04:04:14Z					biological_process											owl:Class	
GO:0008569	biolink:NamedThing	minus-end-directed microtubule motor activity	A motor activity that generates movement along a microtubule toward the minus end, driven by ATP hydrolysis.	tmpzr1t_l9r_go_relaxed.owl	ATP-dependent minus-end-directed microtubule motor activity|microtubule motor activity, minus-end-directed|kinesin ATP phosphohydrolase (minus-end-directed)|ATP-dependent microtubule motor activity, minus-end-directed|dynein ATPase|minus-end-directed ATP-dependent microtubule motor activity|minus-end-directed kinesin ATPase activity	https://github.com/geneontology/go-ontology/issues/18664|https://github.com/geneontology/go-ontology/issues/21289			MetaCyc:3.6.4.5-RXN									molecular_function											owl:Class	
GO:0070651	biolink:NamedThing	nonfunctional rRNA decay	An rRNA catabolic process that results in the targeted detection and degradation of aberrant rRNAs contained within translationally defective ribosomes, thereby acting as a quality-control system.	tmpzr1t_l9r_go_relaxed.owl	NRD							mah	2009-05-28T02:22:49Z					biological_process											owl:Class	
GO:0110080	biolink:NamedThing	positive regulation of placenta blood vessel development	Any process that activates or increases the frequency, rate or extent of placenta blood vessel development.	tmpzr1t_l9r_go_relaxed.owl								kmv	2018-02-01T14:55:30Z					biological_process											owl:Class	
GO:0036106	biolink:NamedThing	peroxisome membrane class-2 targeting sequence binding	Binding to a class II peroxisomal membrane targeting sequence, any of several sequences of amino acids within a protein that can act as a signal for the localization of the protein into the peroxisome membrane in a PEX19-independent manner.	tmpzr1t_l9r_go_relaxed.owl	class 2 mPTS binding|PEX19-independent mPTS binding					Currently identified mPTSs vary greatly in length, and cannot be distinguished by primary structure analysis, suggesting that the peroxisomal sorting information is not contained within a specific amino acid sequence. There do however appear to be two classes of mPTSs: class 1 mPTSs that are bound by PEX19 and imported in a PEX19-dependent manner, and class 2 mPTSs that are not bound by PEX19 and mediate protein import independently of PEX19. The two classes cannot be defined based on their amino acid sequence.		bf	2012-01-27T02:02:22Z					molecular_function											owl:Class	
GO:0102393	biolink:NamedThing	decanoyl-[acp] 2-dehydrogenase activity	Catalysis of the reaction: FAD + H+ + a decanoyl-HmqF protein <=> FADH2(2-) + a 2,3-dehydro-decanoyl-HmqF.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-13624									molecular_function											owl:Class	
GO:0034920	biolink:NamedThing	pyrene dioxygenase activity	Catalysis of the reaction: pyrene + 2 H+ + 2 e- + O2 = cis-4,5-dihydroxy-4,5-dihydropyrene.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0934|EC:1.13.11.-									molecular_function											owl:Class	
GO:1990931	biolink:NamedThing	mRNA N6-methyladenosine dioxygenase activity	Catalysis of the oxidative demethylation of N6-methyladenosine RNA, with concomitant decarboxylation of 2-oxoglutarate and releases oxidized methyl group on N6-methyladenosine as formaldehyde.	tmpzr1t_l9r_go_relaxed.owl	RNA N6-methyladenosine dioxygenase activity|mRNA N(6)-methyladenine demethylase|mRNA N(6)-methyladenosine dioxygenase activity	https://github.com/geneontology/go-ontology/issues/21812			EC:1.14.11.53|RHEA:49520			sp	2016-03-10T08:10:10Z					molecular_function											owl:Class	
GO:0097175	biolink:NamedThing	1,6-anhydro-N-acetyl-beta-muramic acid catabolic process	The chemical reactions and pathways resulting in the breakdown of 1,6-anhydro-N-acetylmuramic acid, the 1,6-anhydro-derivative of N-acetyl-beta-muramic acid.	tmpzr1t_l9r_go_relaxed.owl	1,6-anhydro-N-acetyl-beta-muramate catabolic process|1,6-anhydro-N-acetylmuramate degradation|1,6-anhydro-N-acetylmuramic acid breakdown|1,6-anhydro-N-acetylmuramic acid catabolism|1,6-anhydro-N-acetyl-beta-muramic acid catabolism|1,6-anhydro-N-acetylmuramic acid catabolic process|1,6-anhydro-N-acetyl-beta-muramic acid breakdown|1,6-anhydro-N-acetylmuramate catabolic process|1,6-anhydro-N-acetyl-beta-muramate breakdown|1,6-anhydro-N-acetyl-beta-muramate catabolism|1,6-anhydro-N-acetylmuramate catabolism|1,6-anhydro-N-acetylmuramate breakdown|1,6-anhydro-N-acetyl-beta-muramate degradation|1,6-anhydro-N-acetyl-beta-muramic acid degradation|1,6-anhydro-N-acetylmuramic acid degradation							pr	2011-10-07T12:58:32Z					biological_process											owl:Class	
GO:0009899	biolink:NamedThing	ent-kaurene synthase activity	Catalysis of the reaction: ent-copalyl diphosphate = ent-kaur-16-ene + diphosphate.	tmpzr1t_l9r_go_relaxed.owl	ent-kaurene synthetase B activity|ent-copalyl-diphosphate diphosphate-lyase (cyclizing)|ent-copalyl-diphosphate diphosphate-lyase (cyclizing, ent-kaurene-forming)|ent-kaurene synthase B activity				RHEA:22220|MetaCyc:4.2.3.19-RXN|EC:4.2.3.19|KEGG_REACTION:R05092									molecular_function											owl:Class	
GO:0004989	biolink:NamedThing	octopamine receptor activity	Combining with the biogenic amine octopamine to initiate a change in cell activity. Octopamine is found in both vertebrates and invertebrates and can have properties both of a hormone and a neurotransmitter and acts as an adrenergic agonist.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0006893	biolink:NamedThing	Golgi to plasma membrane transport	The directed movement of substances from the Golgi to the plasma membrane in transport vesicles that move from the trans-Golgi network to the plasma membrane, where they fuse and release their contents by exocytosis.	tmpzr1t_l9r_go_relaxed.owl	Golgi to plasma membrane vesicle-mediated transport													biological_process											owl:Class	
GO:0010225	biolink:NamedThing	response to UV-C	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-C radiation stimulus. UV-C radiation (UV-C light) spans the wavelengths 100 to 280 nm.	tmpzr1t_l9r_go_relaxed.owl	response to UV-C radiation stimulus|response to UV-C light stimulus|response to germicidal ultraviolet radiation stimulus|response to UVC radiation stimulus|response to shortwave ultraviolet radiation stimulus|response to germicidal ultraviolet light stimulus|response to shortwave ultraviolet light stimulus|response to UVC light stimulus													biological_process											owl:Class	
GO:0071740	biolink:NamedThing	IgD B cell receptor complex	An IgD immunoglobulin complex that is present in the plasma membrane of B cells and is composed of two identical immunoglobulin heavy chains of the IgD isotype and two identical immunoglobulin light chains and a signaling subunit, a heterodimer of the Ig-alpha and Ig-beta proteins.	tmpzr1t_l9r_go_relaxed.owl	surface IgD|membrane-bound IgD					Note that an IgD immunoglobulin complex has the function of antigen binding if a suitable antigen is available.		mah	2010-03-24T01:44:53Z					cellular_component											owl:Class	
GO:0070433	biolink:NamedThing	negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway	Any process that stops, prevents, or reduces the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing 2 (NOD2) pathway.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of nucleotide-binding oligomerization domain containing 2 signalling pathway|negative regulation of NOD2 signaling pathway													biological_process											owl:Class	
GO:0050124	biolink:NamedThing	N-acylneuraminate-9-phosphatase activity	Catalysis of the reaction: N-acylneuraminate 9-phosphate + H2O = N-acylneuraminate + phosphate.	tmpzr1t_l9r_go_relaxed.owl	acylneuraminate 9-phosphatase activity|N-acylneuraminic (sialic) acid 9-phosphatase activity|N-acylneuraminic acid 9-phosphate phosphatase activity|N-acylneuraminate-9-phosphate phosphohydrolase activity				RHEA:13057|EC:3.1.3.29|Reactome:R-HSA-4084989|MetaCyc:N-ACYLNEURAMINATE-9-PHOSPHATASE-RXN									molecular_function											owl:Class	
GO:1990165	biolink:NamedThing	single-strand break-containing DNA binding	Binding to damaged DNA containing single-strand breaks (SSBs).	tmpzr1t_l9r_go_relaxed.owl	single-strand break-containing damaged DNA binding|SSB-containing DNA binding							pr	2013-08-08T11:16:04Z					molecular_function											owl:Class	
GO:0002539	biolink:NamedThing	prostaglandin production involved in inflammatory response	The synthesis or release of any prostaglandin following a stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels.	tmpzr1t_l9r_go_relaxed.owl	prostaglandin production involved in acute inflammatory response													biological_process											owl:Class	
GO:0050298	biolink:NamedThing	stizolobinate synthase activity	Catalysis of the reaction: 3,4-dihydroxy-L-phenylalanine + O2 = 5-(L-alanin-3-yl)-2-hydroxy-cis,cis-muconate 6-semialdehyde.	tmpzr1t_l9r_go_relaxed.owl	3,4-dihydroxy-L-phenylalanine:oxygen 2,3-oxidoreductase (recyclizing)				MetaCyc:STIZOLOBINATE-SYNTHASE-RXN|EC:1.13.11.30|RHEA:18465									molecular_function											owl:Class	
GO:0070180	biolink:NamedThing	large ribosomal subunit rRNA binding	Binding to large ribosomal subunit RNA (LSU rRNA), a constituent of the large ribosomal subunit. In S. cerevisiae, this is the 25S rRNA.	tmpzr1t_l9r_go_relaxed.owl	25S rRNA binding|LSU rRNA binding													molecular_function											owl:Class	
GO:0031774	biolink:NamedThing	leukotriene receptor binding	Binding to a leukotriene receptor.	tmpzr1t_l9r_go_relaxed.owl	leukotriene receptor ligand													molecular_function											owl:Class	
GO:0080171	biolink:NamedThing	lytic vacuole organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lytic vacuole.	tmpzr1t_l9r_go_relaxed.owl	lytic vacuole organisation|lytic vacuolar assembly|lytic vacuole biogenesis|lytic vacuole organization and biogenesis							dhl	2011-04-25T04:40:46Z					biological_process											owl:Class	
GO:0097692	biolink:NamedThing	histone H3-K4 monomethylation	The modification of histone H3 by addition of one methyl group to lysine at position 4 of the histone.	tmpzr1t_l9r_go_relaxed.owl								pr	2015-11-05T11:23:15Z					biological_process											owl:Class	
GO:0043333	biolink:NamedThing	2-octaprenyl-6-methoxy-1,4-benzoquinone methylase activity	Catalysis of the reaction: 2-octaprenyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-methionine = 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-homocysteine.	tmpzr1t_l9r_go_relaxed.owl	2-octaprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity	https://github.com/geneontology/go-ontology/issues/15686			EC:2.1.1.201|MetaCyc:2-OCTAPRENYL-METHOXY-BENZOQ-METH-RXN	Note that the polyprenyl sidechain substrate for these methyltransferases varies in length between species, for example, 6 units in S. cerevisiae, 8 units in E. coli and 10 units in G. suboxidans. Where the length of the substrate polyprenyl chain is unknown, the term '2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity ; GO:0008425' should be used.						GO:0102005		molecular_function											owl:Class	
GO:0048312	biolink:NamedThing	intracellular distribution of mitochondria	Any process that establishes the spatial arrangement of mitochondria within the cell.	tmpzr1t_l9r_go_relaxed.owl	mitochondrion positioning within cell|mitochondria positioning within cell													biological_process											owl:Class	
GO:0035584	biolink:NamedThing	calcium-mediated signaling using intracellular calcium source	A series of molecular signals in which a cell uses calcium ions released from an intracellular store to convert a signal into a response.	tmpzr1t_l9r_go_relaxed.owl	calcium signaling using intracellular calcium source|calcium signalling using intracellular calcium source|calcium-mediated signalling using intracellular calcium source							bf	2010-10-18T11:01:08Z					biological_process											owl:Class	
GO:0050118	biolink:NamedThing	N-acetyldiaminopimelate deacetylase activity	Catalysis of the reaction: N-acetyl-LL-2,6-diaminopimelate + H(2)O = LL-2,6-diaminopimelate + acetate.	tmpzr1t_l9r_go_relaxed.owl	N6-acetyl-LL-2,6-diaminoheptanedioate amidohydrolase activity|N-acetyl-LL-diaminopimelate deacylase activity|6-N-acetyl-LL-2,6-diaminoheptanedioate amidohydrolase activity|N-acetyl-L-diaminopimelic acid deacylase activity				EC:3.5.1.47|KEGG_REACTION:R02733|MetaCyc:N-ACETYLDIAMINOPIMELATE-DEACETYLASE-RXN|RHEA:20405									molecular_function											owl:Class	
GO:0047494	biolink:NamedThing	serine-phosphoethanolamine synthase activity	Catalysis of the reaction: L-serine + CDP-ethanolamine = L-serine-phosphoethanolamine + CMP + H(+).	tmpzr1t_l9r_go_relaxed.owl	CDP-ethanolamine:L-serine ethanolamine phosphotransferase activity|serine-phosphinico-ethanolamine synthase activity|serine ethanolamine phosphodiester synthase activity|serine ethanolaminephosphotransferase activity|serine ethanolamine phosphate synthetase activity|serinephosphoethanolamine synthase activity				RHEA:22656|KEGG_REACTION:R02563|EC:2.7.8.4|MetaCyc:SERINE-PHOSPHOETHANOLAMINE-SYNTHASE-RXN									molecular_function											owl:Class	
GO:0000352	biolink:NamedThing	trans assembly of SL-containing precatalytic spliceosome	Assembly of a spliceosomal complex containing the SL RNA and the pre-mRNA to be joined, as well as all the spliceosomal snRNPs involved in trans leader splicing. Formation of the trans leader spliceosome brings together the quadruple SL/U4/U5/U6 snRNP and the complex of the U2 snRNP with the splice site of the pre-mRNA.	tmpzr1t_l9r_go_relaxed.owl	trans assembly of spliced leader-containing precatalytic spliceosome													biological_process											owl:Class	
GO:0098030	biolink:NamedThing	icosahedral viral capsid, neck	A region of constriction located below the head and above the tail sheath of viruses with contractile tails (Myoviridae).	tmpzr1t_l9r_go_relaxed.owl								bm	2012-07-19T14:56:28Z					cellular_component											owl:Class	
GO:0033476	biolink:NamedThing	indoleacetic acid ester conjugate biosynthetic process	The chemical reactions and pathways resulting in the formation of an indole-3-acetic acid amide conjugate, a form of indoleacetic acid covalently bound to an a sugar or polyol through an ester bond.	tmpzr1t_l9r_go_relaxed.owl	indole acetic acid ester conjugate biosynthetic process|indoleacetic acid ester conjugate synthesis|indole acetic acid ester conjugate biosynthesis|indoleacetic acid ester conjugate anabolism|indoleacetic acid ester conjugate formation|indoleacetic acid ester conjugate biosynthesis|IAA ester conjugate biosynthetic process				MetaCyc:PWY-1741									biological_process											owl:Class	
GO:0019361	biolink:NamedThing	2'-(5''-triphosphoribosyl)-3'-dephospho-CoA biosynthetic process	The chemical reactions and pathways resulting in the formation of 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA, a derivative of coenzyme A.	tmpzr1t_l9r_go_relaxed.owl	2'-(5''-triphosphoribosyl)-3'-dephospho-CoA synthesis|2'-(5''-triphosphoribosyl)-3'-dephospho-CoA anabolism|2'-(5''-triphosphoribosyl)-3'-dephospho-CoA formation|2'-(5''-triphosphoribosyl)-3'-dephospho-CoA biosynthesis				MetaCyc:P2-PWY									biological_process											owl:Class	
GO:0050389	biolink:NamedThing	uronolactonase activity	Catalysis of the reaction: D-glucurono-6,2-lactone + H2O = D-glucuronate.	tmpzr1t_l9r_go_relaxed.owl	D-glucurono-6,2-lactone lactonohydrolase activity|glucuronolactonase activity				EC:3.1.1.19|MetaCyc:URONOLACTONASE-RXN|RHEA:13337									molecular_function											owl:Class	
GO:0033324	biolink:NamedThing	choline biosynthetic process via N-monomethylethanolamine	The chemical reactions and pathways resulting in the formation of choline (2-hydroxyethyltrimethylammonium), via the intermediate N-monomethylethanolamine.	tmpzr1t_l9r_go_relaxed.owl	choline formation via N-monomethylethanolamine|choline anabolism via N-monomethylethanolamine|choline synthesis via N-monomethylethanolamine|choline biosynthesis via N-monomethylethanolamine				MetaCyc:PWY-3542|MetaCyc:PWY-4762									biological_process											owl:Class	
GO:0035533	biolink:NamedThing	positive regulation of chemokine (C-C motif) ligand 6 production	Any process that activates or increases the frequency, rate, or extent of production of chemokine (C-C motif) ligand 6 (CCL6).	tmpzr1t_l9r_go_relaxed.owl	positive regulation of chemokine (C-C motif) ligand 6 secretion|positive regulation of CCL6 production							bf	2010-05-07T10:24:21Z			GO:0035537		biological_process											owl:Class	
GO:0018741	biolink:NamedThing	alkyl sulfatase activity	Catalysis of the reaction: dodecyl sulfate + H2O = sulfate + H+ + 1-dodecanol.	tmpzr1t_l9r_go_relaxed.owl	alkyl sulphatase activity				EC:3.1.6.-|UM-BBD_reactionID:r0602									molecular_function											owl:Class	
GO:0032040	biolink:NamedThing	small-subunit processome	A large ribonucleoprotein complex that is an early preribosomal complex. In S. cerevisiae, it has a size of 80S and consists of the 35S pre-rRNA, early-associating ribosomal proteins most of which are part of the small ribosomal subunit, the U3 snoRNA and associated proteins.	tmpzr1t_l9r_go_relaxed.owl	SSU processome|small subunit processome													cellular_component											owl:Class	
GO:0005000	biolink:NamedThing	vasopressin receptor activity	Combining with vasopressin to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	vasopressin activated calcium mobilizing receptor activity											GO:0016931		molecular_function											owl:Class	
GO:0140373	biolink:NamedThing	histone H3-K14 ubiquitination	The modification of histone H3 by the addition of one or more ubiquitin groups to a lysine residue at position 14 of the histone.	tmpzr1t_l9r_go_relaxed.owl	histone H3K14 ubiquitination|histone H3 ubiquitination at K14|histone H3-K14 ubiquitylation							pg	2019-10-03T15:31:15Z					biological_process											owl:Class	
GO:0098605	biolink:NamedThing	selenocystathionine beta-synthase activity	Catalysis of the reaction: L-Serine + Selenohomocysteine => L-Selenocystathionine + H2O.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-2408559			dos	2014-04-16T11:07:50Z					molecular_function											owl:Class	
GO:1990540	biolink:NamedThing	mitochondrial manganese ion transmembrane transport	The process in which a manganese ion is transported across a mitochondrial membrane, into or out of the mitochondrion.	tmpzr1t_l9r_go_relaxed.owl								vw	2014-11-19T11:03:09Z					biological_process											owl:Class	
GO:0033586	biolink:NamedThing	L-phenylalanine biosynthetic process from chorismate via L-arogenate	The chemical reactions and pathways resulting in the formation of L-phenylalanine from other compounds, including chorismate, via the intermediate L-arogenate.	tmpzr1t_l9r_go_relaxed.owl	L-phenylalanine formation from chorismate via L-arogenate|L-phenylalanine biosynthesis from chorismate via L-arogenate|L-phenylalanine anabolism from chorismate via L-arogenate|L-phenylalanine synthesis from chorismate via L-arogenate				MetaCyc:PWY-3462									biological_process											owl:Class	
GO:0015010	biolink:NamedThing	tetrahydrocorphin metabolic process	The chemical reactions and pathways involving tetrahydrocorphins, tetrapyrroles that combine the structural elements of both porphyrins and corrins.	tmpzr1t_l9r_go_relaxed.owl	tetrahydrocorphin metabolism													biological_process											owl:Class	
GO:0015011	biolink:NamedThing	nickel-tetrapyrrole coenzyme metabolic process	The chemical reactions and pathways involving an enzyme cofactor consisting of a tetrapyrrole structure containing nickel, such as the F-430 cofactor found in methyl-coenzyme M reductase.	tmpzr1t_l9r_go_relaxed.owl	nickel-tetrapyrrole coenzyme metabolism|coenzyme F430 metabolic process													biological_process											owl:Class	
GO:0106147	biolink:NamedThing	fraxetin biosynthesis	The chemical reactions and pathways resulting in the formation of fraxetin.	tmpzr1t_l9r_go_relaxed.owl								hjd	2018-09-07T18:32:47Z					biological_process											owl:Class	
GO:0090060	biolink:NamedThing	regulation of metaxylem development	Any process that modulates the frequency, rate, or extent of metaxylem development. Metaxylem development is the process whose specific outcome is the progression of the metaxylem over time, from its formation to the mature structure. The metaxylem is the part of the primary xylem that differentiates after the protoxylem and before the secondary xylem, if any of the latter is formed.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-08-11T03:14:54Z					biological_process											owl:Class	
GO:0140368	biolink:NamedThing	decoy receptor complex	A receptor complex that recognizes, binds and sequesters a specific receptor ligand to prevent it from binding to its regular receptor. May be soluble or membrane bound.	tmpzr1t_l9r_go_relaxed.owl	osteoprotegerin complex|osteoclastogenesis inhibitory factor							pg	2019-09-13T16:39:24Z					cellular_component											owl:Class	
GO:0004118	biolink:NamedThing	cGMP-stimulated cyclic-nucleotide phosphodiesterase activity	Catalysis of the reaction: nucleoside 3',5'-cyclic phosphate + H2O = nucleoside 5'-phosphate; catalytic activity is increased in the presence of cGMP.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0072344	biolink:NamedThing	rescue of stalled ribosome	A process of translational elongation that takes place when a ribosome has stalled during translation, and results in freeing the ribosome from the stalled translation complex.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/6481|https://github.com/geneontology/go-ontology/issues/22227						mah	2010-11-10T11:54:26Z					biological_process											owl:Class	
GO:0071651	biolink:NamedThing	positive regulation of chemokine (C-C motif) ligand 5 production	Any process that activates or increases the frequency, rate, or extent of production of chemokine (C-C motif) ligand 5.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of RANTES production|positive regulation of Regulated upon Activation, Normal T-cell Expressed, and Secreted production|positive regulation of CCL5 production							mah	2010-02-12T10:40:19Z					biological_process											owl:Class	
GO:0047260	biolink:NamedThing	alpha,alpha-trehalose-phosphate synthase (GDP-forming) activity	Catalysis of the reaction: GDP-D-glucose + glucose-6-phosphate = alpha,alpha-trehalose 6-phosphate + GDP.	tmpzr1t_l9r_go_relaxed.owl	guanosine diphosphoglucose-glucose phosphate glucosyltransferase activity|GDP-glucose:D-glucose-6-phosphate 1-alpha-D-glucosyltransferase activity|GDPglucose:D-glucose-6-phosphate 1-alpha-D-glucosyltransferase activity|GDPglucose-glucose-phosphate glucosyltransferase activity|trehalose phosphate synthase (GDP-forming) activity|GDP-glucose-glucosephosphate glucosyltransferase activity				MetaCyc:2.4.1.36-RXN|EC:2.4.1.36|RHEA:14605									molecular_function											owl:Class	
GO:0052848	biolink:NamedThing	inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity	Catalysis of the reaction: 3,5-bisdiphosphoinositol-1D-myo-inositol 2,3,4,6-tetrakisphosphate + H2O = 3-diphospho-1D-myo-inositol 1,2,4,5,6-pentakisphosphate + phosphate + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-10976			ai	2011-12-05T11:02:23Z					molecular_function											owl:Class	
GO:0085020	biolink:NamedThing	protein K6-linked ubiquitination	A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 6 of the ubiquitin monomers, is added to a protein. K6-linked ubiquitination is involved in DNA repair.	tmpzr1t_l9r_go_relaxed.owl	protein K6-linked polyubiquitination							jl	2010-06-01T03:05:03Z					biological_process											owl:Class	
GO:0031814	biolink:NamedThing	P2Y4 nucleotide receptor binding	Binding to a P2Y4 nucleotide receptor.	tmpzr1t_l9r_go_relaxed.owl	P2Y4 nucleotide receptor ligand													molecular_function											owl:Class	
GO:0102769	biolink:NamedThing	dihydroceramide glucosyltransferase activity	Catalysis of the reaction: UDP-alpha-D-glucose + a dihydroceramide = UDP + H+ + a D-glucosyl-N-acylsphinganine.	tmpzr1t_l9r_go_relaxed.owl					EC:2.4.1.80|MetaCyc:RXN-7793									molecular_function											owl:Class	
GO:1905575	biolink:NamedThing	ganglioside GM3 binding	Binding to ganglioside GM3.	tmpzr1t_l9r_go_relaxed.owl								pga	2016-10-19T11:17:10Z					molecular_function											owl:Class	
GO:0070619	biolink:NamedThing	Shc-Grb2-Sos complex	A protein complex that contains Grb2, the adaptor protein Shc and the guanine nucleotide exchange factor Sos (or an ortholog thereof, such as mSos1), and is involved in linking EGFR activation to the p21-Ras pathway.	tmpzr1t_l9r_go_relaxed.owl	Shc-Grb2-mSos1 complex, EGF stimulated							mah	2009-04-29T04:30:00Z					cellular_component											owl:Class	
GO:0043431	biolink:NamedThing	2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinone methyltransferase activity	Catalysis of the reaction: 2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinol + S-adenosyl-L-methionine = ubiquinol + S-adenosyl-L-homocysteine.	tmpzr1t_l9r_go_relaxed.owl	3-demethylubiquinone-9 3-methyltransferase activity|2-octaprenyl-6-hydroxy phenol methylase activity				MetaCyc:2.1.1.64-RXN									molecular_function											owl:Class	
GO:0010814	biolink:NamedThing	substance P catabolic process	The chemical reactions and pathways resulting in the breakdown of the neuropeptide substance P.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0032089	biolink:NamedThing	NACHT domain binding	Binding to a NACHT (NAIP, CIITA, HET-E and TP1) domain. The NACHT domain consists of seven distinct conserved motifs, including an ATP/GTPase specific P-loop, a Mg(2+)-binding site and five more specific motifs.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0062182	biolink:NamedThing	all-trans retinoic acid 4-hydrolase activity	Catalysis of the reaction: all-trans-retinoate + O2 + reduced [NADPH--hemoprotein reductase] = all-trans-(4S)-hydroxyretinoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase].	tmpzr1t_l9r_go_relaxed.owl					RHEA:51492			dph	2019-11-26T18:36:06Z					molecular_function											owl:Class	
GO:1990455	biolink:NamedThing	PTEN phosphatase complex	A phospholipid phosphatase complex that catalyses the hydrolysis of the second messenger PtdIns (3,4,5)P3. Will also dephosphorylate PtdIns(3,4)P2, PtdIns3P, and Ins(1,3,4,5)P4. Dimerization is critical for its lipid phosphatase function.	tmpzr1t_l9r_go_relaxed.owl	phosphatase and tensin homolog|phosphatase and tensin homolog deleted on chromosome ten homodimer|phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN homodimer					An example of this is PTEN in human (P60484) in PMID:24766807 (inferred from direct assay).		bhm	2014-08-13T10:21:20Z					cellular_component											owl:Class	
GO:0030290	biolink:NamedThing	sphingolipid activator protein activity	Any of a group of peptide cofactors of enzymes for the lysosomal degradation of sphingolipids. They stimulate various enzymes, including glucosylceramidase, galactosylceramidase, cerebroside-sulfatase, alpha-galactosidase, beta-galactosidase, and sphingomyelin phosphodiesterase.	tmpzr1t_l9r_go_relaxed.owl	saposin				Reactome:R-HSA-1605717									molecular_function											owl:Class	
GO:1902246	biolink:NamedThing	cis-abienol biosynthetic process	The chemical reactions and pathways resulting in the formation of cis-abienol.	tmpzr1t_l9r_go_relaxed.owl	cis-abienol biosynthesis|cis-abienol anabolism|cis-abienol formation|cis-abienol synthesis							ms	2013-06-20T09:10:02Z					biological_process											owl:Class	
GO:0003855	biolink:NamedThing	3-dehydroquinate dehydratase activity	Catalysis of the reaction: 3-dehydroquinate = 3-dehydroshikimate + H(2)O.	tmpzr1t_l9r_go_relaxed.owl	3-dehydroquinate hydro-lyase (3-dehydroshikimate-forming)|3-dehydroquinase activity|3-dehydroquinate hydro-lyase activity|dehydroquinate dehydratase activity|dehydroquinase activity|5-dehydroquinate hydro-lyase activity|3-dehydroquinate hydrolase activity|5-dehydroquinase activity|DHQase|5-dehydroquinate dehydratase activity				EC:4.2.1.10|RHEA:21096|MetaCyc:3-DEHYDROQUINATE-DEHYDRATASE-RXN|KEGG_REACTION:R03084									molecular_function											owl:Class	
GO:0072591	biolink:NamedThing	citrate-L-glutamate ligase activity	Catalysis of the reaction: ATP + citrate + L-glutamate = ADP + phosphate + beta-citryl-L-glutamate.	tmpzr1t_l9r_go_relaxed.owl								mah	2011-02-10T03:24:26Z					molecular_function											owl:Class	
GO:0015554	biolink:NamedThing	tartrate transmembrane transporter activity	Enables the transfer of tartrate from one side of a membrane to the other. Tartrate is the anion of 2,3-dihydroxybutanedioic acid, one of the aldaric acids. The L(+) enantiomer occurs widely in plants, especially in grape juice, and in fungi and bacteria.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0021991	biolink:NamedThing	neural plate thickening	The process of apical-basal elongation of individual ectodermal cells during the formation of the neural placode.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0140674	biolink:NamedThing	ATP-dependent histone loader activity	Depositing a histone or a histone complex onto DNA.	tmpzr1t_l9r_go_relaxed.owl	histone loader activity|histone loading activity	https://github.com/geneontology/go-ontology/issues/21733						pg	2021-06-29T12:42:57Z					molecular_function											owl:Class	
GO:0036322	biolink:NamedThing	pancreatic polypeptide secretion	The regulated release of pancreatic polypeptide (PP) from a cell. Pancreatic polypeptide is a 36 amino acid polypeptide secreted by islets of Langerhans cells in the pancreas.	tmpzr1t_l9r_go_relaxed.owl	PP secretion							bf	2012-09-04T14:39:03Z					biological_process											owl:Class	
GO:1903864	biolink:NamedThing	P granule disassembly	The disaggregation of a P granule into its constituent components.	tmpzr1t_l9r_go_relaxed.owl	polar granule disassembly|germline granule disassembly							kmv	2015-02-04T15:27:12Z					biological_process											owl:Class	
GO:0097512	biolink:NamedThing	cardiac myofibril	A cardiac myofibril is a myofibril specific to cardiac muscle cells.	tmpzr1t_l9r_go_relaxed.owl								pr	2013-10-16T13:04:58Z					cellular_component											owl:Class	
GO:0031718	biolink:NamedThing	type 1 cannabinoid receptor binding	Binding to a type 1 cannabinoid receptor.	tmpzr1t_l9r_go_relaxed.owl	type 1 cannabinoid receptor ligand													molecular_function											owl:Class	
GO:0047634	biolink:NamedThing	agmatine N4-coumaroyltransferase activity	Catalysis of the reaction: 4-coumaroyl-CoA + agmatine = N-(4-guanidiniumylbutyl)-4-hydroxycinnamamide + CoA + H(+).	tmpzr1t_l9r_go_relaxed.owl	4-coumaroyl-CoA:agmatine N4-coumaroyltransferase activity|agmatine coumaroyltransferase activity|4-coumaroyl-CoA:agmatine 4-N-coumaroyltransferase activity|p-coumaroyl-CoA-agmatine N-p-coumaroyltransferase activity				EC:2.3.1.64|KEGG_REACTION:R01617|MetaCyc:AGMATINE-N4-COUMAROYLTRANSFERASE-RXN|RHEA:13405									molecular_function											owl:Class	
GO:0097246	biolink:NamedThing	catechin binding	Binding to a catechin, a polyphenolic antioxidant plant metabolite with a flavonoid or flavan-3-ol structure.	tmpzr1t_l9r_go_relaxed.owl								pr	2012-02-17T03:53:54Z					molecular_function											owl:Class	
GO:0102062	biolink:NamedThing	alpha-santalene synthase activity	Catalysis of the reaction: 2-cis,6-cis-farnesyl diphosphate <=> (+)-alpha-santalene + diphosphoric acid.	tmpzr1t_l9r_go_relaxed.owl					RHEA:30463|EC:4.2.3.50|MetaCyc:RXN-10567									molecular_function											owl:Class	
GO:0018429	biolink:NamedThing	copper incorporation into copper-sulfur cluster via heptakis-L-histidino tetracopper mu4-sulfide hydroxide	The incorporation of copper into a 4Cu-S copper-sulfur cluster via heptakis-L-histidino tetracopper mu4-sulfide hydroxide.	tmpzr1t_l9r_go_relaxed.owl	copper incorporation into copper-sulphur cluster via heptakis-L-histidino tetracopper mu4-sulphide hydroxide				RESID:AA0298									biological_process											owl:Class	
GO:0018428	biolink:NamedThing	copper incorporation into copper-sulfur cluster	The incorporation of copper into a copper-sulfur cluster.	tmpzr1t_l9r_go_relaxed.owl	copper incorporation into copper-sulphur cluster													biological_process											owl:Class	
GO:0052845	biolink:NamedThing	inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity	Catalysis of the reaction: inositol 5-diphosphate 1,2,3,4,6-pentakisphosphate + H2O = inositol 1,2,3,4,5,6-hexakisphosphate + phosphate + 2 H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-10964			ai	2011-12-05T10:59:20Z					molecular_function											owl:Class	
GO:0102691	biolink:NamedThing	UDP-glucose:benzyladenine 7-N-glucosyltransferase activity	Catalysis of the reaction: UDP-alpha-D-glucose + N-benzyladenine <=> H+ + benzyladenine-7-N-glucoside + UDP.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-4729									molecular_function											owl:Class	
GO:0097736	biolink:NamedThing	aerial mycelium formation	The process by which hyphae grow in an upward or outward direction from the surface of the substrate; from there, propagative spores develop in or on characteristic structures that are distinctive of some fungal and bacterial species. The species that form an aerial mycelium develop conidiophores at the ends of the aerial hyphae.	tmpzr1t_l9r_go_relaxed.owl	fertile mycelium formation|aerial hyphal growth							pr	2016-10-14T14:25:22Z					biological_process											owl:Class	
GO:0004650	biolink:NamedThing	polygalacturonase activity	Catalysis of the random hydrolysis of (1->4)-alpha-D-galactosiduronic linkages in pectate and other galacturonans.	tmpzr1t_l9r_go_relaxed.owl	pectolase activity|endo-D-galacturonase activity|endogalacturonase activity|endopolygalacturonase activity|poly(1,4-alpha-D-galacturonide) glycanohydrolase activity|pectinase activity|pectin depolymerase activity|pectin hydrolase activity|poly-alpha-1,4-galacturonide glycanohydrolase activity|endo-polygalacturonase activity|pectin polygalacturonase activity				EC:3.2.1.15|MetaCyc:RXN-2103									molecular_function											owl:Class	
GO:0021894	biolink:NamedThing	cerebral cortex GABAergic interneuron development	The process whose specific outcome is the progression of a cerebral cortex GABAergic interneuron over time, from initial commitment to its fate, to the fully functional differentiated cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0052833	biolink:NamedThing	inositol monophosphate 4-phosphatase activity	Catalysis of the reaction: myo-inositol 4-phosphate + H2O = myo-inositol + phosphate.	tmpzr1t_l9r_go_relaxed.owl	inositol-1(or 4)-monophosphatase activity|myo-inositol-1(or 4)-monophosphatase activity|myo-inositol-1(or 4)-phosphate phosphohydrolase activity				RHEA:30735|EC:3.1.3.25|Reactome:R-HSA-1855211|MetaCyc:RXN-10952			ai	2011-11-29T11:02:15Z					molecular_function											owl:Class	
GO:0035236	biolink:NamedThing	proctolin receptor activity	Combining with the neuropeptide proctolin, to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0140450	biolink:NamedThing	protein targeting to Golgi apparatus	The process of targeting specific proteins to the Golgi apparatus. Usually requires an organelle-specific protein sequence motif or a protein modification (for example a palmitoylation).	tmpzr1t_l9r_go_relaxed.owl								pg	2020-04-08T13:10:10Z					biological_process											owl:Class	
GO:0031869	biolink:NamedThing	prostacyclin receptor binding	Binding to a prostacyclin receptor.	tmpzr1t_l9r_go_relaxed.owl	prostacyclin receptor ligand|prostanoid IP receptor binding													molecular_function											owl:Class	
GO:0007624	biolink:NamedThing	ultradian rhythm	The specific actions or reactions of an organism that recur with a regularity more frequent than every 24 hours.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0031219	biolink:NamedThing	levanase activity	Catalysis of the random hydrolysis of 2,6-beta-D-fructofuranosidic linkages in 2,6-beta-D-fructans (levans) containing more than 3 fructose units.	tmpzr1t_l9r_go_relaxed.owl	2,6-beta-D-fructan fructanohydrolase activity|levan hydrolase activity				EC:3.2.1.65|MetaCyc:3.2.1.65-RXN									molecular_function											owl:Class	
GO:0019601	biolink:NamedThing	toluene oxidation via 2-hydroxytoluene	The degradation of toluene to form pyruvate and acetaldehyde; the first step in the pathway is the oxidation of toluene to form 2-hydroxytoluene (o-cresol).	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:TOLUENE-DEG-2-OH-PWY									biological_process											owl:Class	
GO:0008921	biolink:NamedThing	lipopolysaccharide-1,6-galactosyltransferase activity	Catalysis of the reaction: UDP-galactose + lipopolysaccharide = UDP + 1,6 alpha-D-galactosyl-lipopolysaccharide.	tmpzr1t_l9r_go_relaxed.owl	LPS-1,6-galactosyltransferase activity													molecular_function											owl:Class	
GO:0035616	biolink:NamedThing	histone H2B conserved C-terminal lysine deubiquitination	A histone deubiquitination process in which a ubiquitin monomer is removed from a conserved lysine residue in the C-terminus of histone H2B. The conserved lysine residue is K119 in fission yeast, K123 in budding yeast, or K120 in mammals.	tmpzr1t_l9r_go_relaxed.owl	mammalian H2B K120 deubiquitination|budding yeast H2B K123 deubiquitination|fission yeast H2B K119 deubiquitination							bf	2010-12-03T10:36:44Z					biological_process											owl:Class	
GO:0033904	biolink:NamedThing	dextranase activity	Catalysis of the endohydrolysis of 1,6-alpha-D-glucosidic linkages in dextran.	tmpzr1t_l9r_go_relaxed.owl	alpha-1,6-glucan-6-glucanohydrolase activity|endo-dextranase activity|dextran hydrolase activity|dextranase DL 2 activity|DL 2|1,6-alpha-D-glucan 6-glucanohydrolase activity|endodextranase activity|alpha-D-1,6-glucan-6-glucanohydrolase activity				MetaCyc:3.2.1.11-RXN|EC:3.2.1.11									molecular_function											owl:Class	
GO:0043592	biolink:NamedThing	exosporium	The outermost layer of a bacterial endospore, which is loosely attached and located outside of the endospore coat. It is generally composed of protein, carbohydrate, and perhaps lipid.	tmpzr1t_l9r_go_relaxed.owl	perispore|exospore|epispore													cellular_component											owl:Class	
GO:0055015	biolink:NamedThing	ventricular cardiac muscle cell development	The process whose specific outcome is the progression of a ventricular cardiac muscle cell over time, from its formation to the mature state. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction. The ventricle is the part of the heart that pumps blood out of the organ.	tmpzr1t_l9r_go_relaxed.owl	ventricular heart muscle cell development|ventricular cardiomyocyte development													biological_process											owl:Class	
GO:0060814	biolink:NamedThing	posterior mRNA localization involved in anterior/posterior axis specification	Any process in which a mRNA is transported to and maintained in the oocyte and/or syncytial embryo contributing to the specification of the anterior/posterior axis.	tmpzr1t_l9r_go_relaxed.owl	posterior mRNA localisation involved in anterior/posterior axis specification							dph	2009-08-07T09:54:54Z					biological_process											owl:Class	
GO:0039695	biolink:NamedThing	DNA-templated viral transcription	A transcription process that uses a viral DNA as a template.	tmpzr1t_l9r_go_relaxed.owl					VZ:1942			bf	2013-10-28T13:25:20Z					biological_process											owl:Class	
GO:0050689	biolink:NamedThing	negative regulation of defense response to virus by host	Any host process that results in the inhibition of antiviral immune response mechanisms, thereby facilitating viral replication. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of antiviral response by host|negative regulation by host of antiviral response|downregulation of antiviral response by host|down regulation of antiviral response by host|inhibition of antiviral response by host|negative regulation of antiviral response by host													biological_process											owl:Class	
GO:0018616	biolink:NamedThing	trihydroxytoluene dioxygenase activity	Catalysis of the reaction: 2,3,5-trihydroxytoluene + O2 = 2,4,6-trioxoheptanoate.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0093|MetaCyc:R305-RXN									molecular_function											owl:Class	
GO:0071306	biolink:NamedThing	cellular response to vitamin E	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin E stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to DL-alpha-tocopheryl acetate|cellular response to DL-alpha-tocopherol acetate|cellular response to O-Acetyl-alpha-tocopherol							mah	2009-12-10T04:35:58Z					biological_process											owl:Class	
GO:0023002	biolink:NamedThing	nuclear migration to embryo sac poles	Migration of the nuclei of the two-nucleate embryo sac to opposite poles of the cell.	tmpzr1t_l9r_go_relaxed.owl	nucleus migration to female gametophyte poles|nucleus migration to megagametophyte poles|nuclear migration to female gametophyte poles|nucleus migration to embryo sac poles|nuclear migration to megagametophyte poles													biological_process											owl:Class	
GO:0034827	biolink:NamedThing	1,2-dihydroxy-5,6,7,8-tetrahydronaphthalene extradiol dioxygenase activity	Catalysis of the reaction: 1,2-dihydroxy-5,6,7,8-tetrahydronaphthalene + O2 = 4-(2-oxocyclohexyl)-2-hydroxy-buta-2,4-dienoate + H+.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r1171|EC:1.13.11.-									molecular_function											owl:Class	
GO:0010336	biolink:NamedThing	gibberellic acid homeostasis	Any biological process involved in the maintenance of an internal steady state of gibberellic acid; may involve transport, biosynthesis, catabolism or conjugation.	tmpzr1t_l9r_go_relaxed.owl	gibberellin homeostasis													biological_process											owl:Class	
GO:0070181	biolink:NamedThing	small ribosomal subunit rRNA binding	Binding to small ribosomal subunit RNA (SSU rRNA), a constituent of the small ribosomal subunit. In S. cerevisiae, this is the 18S rRNA.	tmpzr1t_l9r_go_relaxed.owl	SSU rRNA binding|18S rRNA binding													molecular_function											owl:Class	
GO:0035398	biolink:NamedThing	helper T cell enhancement of T cell mediated immune response	Positive regulation of a T cell mediated immune response mediated via cytokine production by a helper T cell.	tmpzr1t_l9r_go_relaxed.owl	helper T cell enhancement of T cell mediated immunity|provision of T cell help to T cell							bf	2010-03-23T10:40:00Z					biological_process											owl:Class	
GO:0042452	biolink:NamedThing	deoxyguanosine biosynthetic process	The chemical reactions and pathways resulting in the formation of deoxyguanosine, a nucleoside consisting of the base guanine and the sugar deoxyribose.	tmpzr1t_l9r_go_relaxed.owl	deoxyguanosine biosynthesis|deoxyguanosine formation|deoxyguanosine synthesis|deoxyguanosine anabolism													biological_process											owl:Class	
GO:0062177	biolink:NamedThing	radial spoke assembly	The aggregation, arrangement and bonding together of a set of components to form the radial spoke, a protein complex that links the outer microtubule doublet of the ciliary or flagellum axoneme with the sheath that surrounds the central pair of microtubules.	tmpzr1t_l9r_go_relaxed.owl								dph	2019-11-20T17:50:08Z					biological_process											owl:Class	
GO:0000254	biolink:NamedThing	C-4 methylsterol oxidase activity	Catalysis of the reaction: 4,4-dimethyl-5-alpha-cholesta-8,24-dien-3-beta-ol + NAD(P)H + H(+) + O2 = 4-beta-hydroxymethyl-4-alpha-methyl-5-alpha-cholesta-8,24-dien-3-beta-ol + NAD(P)+ + H2O.	tmpzr1t_l9r_go_relaxed.owl	4-methylsterol oxidase activity|4,4-dimethyl-5alpha-cholest-7-en-3beta-ol,NAD(P)H:oxygen oxidoreductase (hydroxylating)|methylsterol monooxygenase activity|4,4-dimethyl-5alpha-cholest-7-en-3beta-ol,hydrogen-donor:oxygen oxidoreductase (hydroxylating)|methylsterol hydroxylase activity				EC:1.14.18.9|Reactome:R-HSA-194669|MetaCyc:1.14.13.72-RXN|RHEA:55220|Reactome:R-HSA-194641	Note that zymosterol is cholesta-8,24-dien-3-ol.								molecular_function											owl:Class	
GO:0140704	biolink:NamedThing	3',2'-cyclic GMP-AMP binding	Binding to 3',2' cyclic GMP-AMP (cGAMP) nucleotide, a cyclic purine dinucleotide that consists of AMP and GMP units cyclized via 3',5' and 2',5' linkages.	tmpzr1t_l9r_go_relaxed.owl	3',2' cyclic-GMP-AMP binding|3',2'-cyclic GAMP binding|3',2'-cGAMP binding	https://github.com/geneontology/go-ontology/issues/21980						pg	2021-08-27T05:44:28Z					molecular_function											owl:Class	
GO:0034926	biolink:NamedThing	pyrene-4,5-epoxide hydrolase activity	Catalysis of the reaction: pyrene-4,5-oxide + H2O = trans-4,5-dihydroxy-4,5-dihydropyrene.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0942									molecular_function											owl:Class	
GO:0050242	biolink:NamedThing	pyruvate, phosphate dikinase activity	Catalysis of the reaction: ATP + phosphate + pyruvate = AMP + diphosphate + 2 H(+) + phosphoenolpyruvate.	tmpzr1t_l9r_go_relaxed.owl	pyruvate,phosphate dikinase activity|pyruvate-phosphate dikinase (phosphorylating)|pyruvate-inorganic phosphate dikinase activity|pyruvate-phosphate dikinase activity|pyruvic-phosphate dikinase activity|orthophosphate dikinase pyruvate|pyruvate-phosphate ligase activity|PPDK|ATP:pyruvate, phosphate phosphotransferase activity|pyruvic-phosphate ligase activity|pyruvate, Pi dikinase activity|pyruvate,orthophosphate dikinase activity				EC:2.7.9.1|RHEA:10756|KEGG_REACTION:R00206|MetaCyc:PYRUVATEORTHOPHOSPHATE-DIKINASE-RXN									molecular_function											owl:Class	
GO:0003854	biolink:NamedThing	3-beta-hydroxy-delta5-steroid dehydrogenase activity	Catalysis of the reaction: a 3-beta-hydroxy-delta(5)-steroid + NAD+ = a 3-oxo-delta(5)-steroid + NADH + H(+).	tmpzr1t_l9r_go_relaxed.owl	3beta-HSDH|3beta-hydroxy-delta5-steroid dehydrogenase activity|3beta-hydroxy-5-ene steroid dehydrogenase activity|progesterone reductase activity|3beta-hydroxy-5-ene-steroid dehydrogenase activity|3beta-hydroxy-delta5-C27-steroid oxidoreductase|5-ene-3-beta-hydroxysteroid dehydrogenase activity|3beta-hydroxy-5-ene-steroid oxidoreductase activity|3-beta-hydroxy-D5-steroid dehydrogenase activity|steroid-delta5-3beta-ol dehydrogenase activity|3beta-hydroxy steroid dehydrogenase/isomerase activity|3beta-hydroxy-delta5-C27-steroid dehydrogenase/isomerase activity|delta5-3beta-hydroxysteroid dehydrogenase activity|3-beta-hydroxy-5-ene steroid dehydrogenase activity|3beta-hydroxy-delta5-steroid:NAD+ 3-oxidoreductase activity				Reactome:R-HSA-196372|MetaCyc:1.1.1.145-RXN|Reactome:R-HSA-196350|RHEA:24076|Reactome:R-HSA-193816|Reactome:R-HSA-192097|Reactome:R-HSA-193789|EC:1.1.1.145									molecular_function											owl:Class	
GO:0070436	biolink:NamedThing	Grb2-EGFR complex	A protein complex that contains the epidermal growth factor receptor (EGFR) and Grb2, and is involved in linking EGFR activation to the p21-Ras pathway.	tmpzr1t_l9r_go_relaxed.owl	Grb2-Egfr complex, EGF stimulated													cellular_component											owl:Class	
GO:0046258	biolink:NamedThing	anaerobic 2,4,6-trinitrotoluene catabolic process	The chemical reactions and pathways resulting in the breakdown of 2,4,6-trinitrotoluene, 1-methyl-2,4,6-trinitrobenzene, a highly explosive pale yellow crystalline solid, in the absence of oxygen.	tmpzr1t_l9r_go_relaxed.owl	anaerobic 2,4,6-trinitrotoluene degradation|anaerobic 2,4,6-trinitrotoluene catabolism|anaerobic 2,4,6-trinitrotoluene breakdown													biological_process											owl:Class	
GO:0018975	biolink:NamedThing	anaerobic 2,4,6-trinitrotoluene metabolic process	The chemical reactions and pathways involving 2,4,6-trinitrotoluene, 1-methyl-2,4,6-trinitrobenzene, a highly explosive pale yellow crystalline solid, that occur in the absence of oxygen.	tmpzr1t_l9r_go_relaxed.owl	anaerobic 2,4,6-trinitrotoluene metabolism				UM-BBD_pathwayID:tnt2									biological_process											owl:Class	
GO:0061736	biolink:NamedThing	engulfment of target by autophagosome	The membrane invagination process by which an autophagosomal membrane surrounds an object that will be degraded by macroautophagy.	tmpzr1t_l9r_go_relaxed.owl								dph	2015-09-14T14:10:24Z					biological_process											owl:Class	
GO:0017095	biolink:NamedThing	heparan sulfate 6-O-sulfotransferase activity	Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + heparan sulfate = adenosine 3',5'-bisphosphate + heparan sulfate 6-O-sulfate; results in 6-O-sulfation of glucosamine residues in heparan sulfate.	tmpzr1t_l9r_go_relaxed.owl	heparin 6-O-sulfotransferase activity|heparan sulphate 6-O-sulphotransferase activity				Reactome:R-HSA-2076419|EC:2.8.2.-									molecular_function											owl:Class	
GO:0071188	biolink:NamedThing	protocadherin-alpha-v7-protocadherin-gamma-a1 complex	A protein complex that contains the cell adhesion molecules protocadherin-alpha-v7 and protocadherin-gamma-a1, and is involved in the regulation of protein localization to the plasma membrane.	tmpzr1t_l9r_go_relaxed.owl	Pcdha7-Pcdhga1 complex							mah	2009-11-23T04:23:25Z					cellular_component											owl:Class	
GO:0102394	biolink:NamedThing	4-hydroxy-L-isoleucine dehydrogenase activity	Catalysis of the reaction: (2S,3R,4S)-4-hydroxy-L-isoleucine + NAD <=> (2S,3R)-2-amino-3-methyl-4-ketopentanoate + NADH + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-13637									molecular_function											owl:Class	
GO:0047123	biolink:NamedThing	quinoline-4-carboxylate 2-oxidoreductase activity	Catalysis of the reaction: A + H(2)O + quinoline-4-carboxylate = 2-oxo-1,2-dihydroquinoline-4-carboxylate + AH(2).	tmpzr1t_l9r_go_relaxed.owl	quinoline-4-carboxylate:acceptor 2-oxidoreductase (hydroxylating)|quinoline-4-carboxylic acid 2-oxidoreductase activity				RHEA:14949|EC:1.3.99.19|KEGG_REACTION:R05183|MetaCyc:1.3.99.19-RXN									molecular_function											owl:Class	
GO:2001126	biolink:NamedThing	positive regulation of translational frameshifting	Any process that activates or increases the frequency, rate or extent of translational frameshifting.	tmpzr1t_l9r_go_relaxed.owl								dph	2011-10-12T05:52:30Z					biological_process											owl:Class	
GO:0044590	biolink:NamedThing	iron-sulfur-molybdenum cofactor binding	Binding to iron molybdenum cofactor, the cofactor located at the active site of the molybdenum nitrogenase.	tmpzr1t_l9r_go_relaxed.owl	FeMoco binding|FeMo co binding							jl	2012-04-26T02:27:39Z					molecular_function											owl:Class	
GO:1900633	biolink:NamedThing	pentadecane metabolic process	The chemical reactions and pathways involving pentadecane.	tmpzr1t_l9r_go_relaxed.owl	pentadecane metabolism							tt	2012-05-21T06:51:34Z					biological_process											owl:Class	
GO:0033140	biolink:NamedThing	negative regulation of peptidyl-serine phosphorylation of STAT protein	Any process that stops, prevents, or reduces the frequency, rate or extent of the phosphorylation of a serine residue of a STAT (Signal Transducer and Activator of Transcription) protein.	tmpzr1t_l9r_go_relaxed.owl	inhibition of serine phosphorylation of STAT3 protein|downregulation of serine phosphorylation of STAT3 protein|negative regulation of serine phosphorylation of STAT3 protein|down regulation of serine phosphorylation of STAT3 protein|down-regulation of serine phosphorylation of STAT3 protein											GO:1903262		biological_process											owl:Class	
GO:0010284	biolink:NamedThing	lariciresinol reductase activity	Catalysis of the reaction: lariciresinol + NADPH + H+ = secoisolariciresinol + NADP+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-8679|MetaCyc:RXN-8684									molecular_function											owl:Class	
GO:1904551	biolink:NamedThing	cellular response to arachidonic acid	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an arachidonic acid stimulus.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-08-13T20:53:31Z					biological_process											owl:Class	
GO:1990485	biolink:NamedThing	anaerobic lactate catabolic process	The chemical reactions and pathways resulting in the breakdown of lactate (2-hydroxypropanoic acid) in the absence of oxygen.	tmpzr1t_l9r_go_relaxed.owl	anaerobic lactic acid catabolic process							tt	2014-09-20T16:48:06Z					biological_process											owl:Class	
GO:0036511	biolink:NamedThing	trimming of first mannose on A branch	The removal of the first alpha-1,2-linked mannose from the A-chain of a glycoprotein oligosaccharide in the endoplasmic reticulum.	tmpzr1t_l9r_go_relaxed.owl	conversion of (Man)9(GlcNAc)2 to (Man)8A(GlcNAc)2|glycoprotein mannose trimming on A branch|conversion of M9 to M8A					Consider also annotating to 'mannosyl-oligosaccharide 1,2-alpha-mannosidase activity ; GO:0004571'.		bf	2015-06-11T14:14:03Z					biological_process											owl:Class	
GO:0018848	biolink:NamedThing	pinocarveol isomerase activity	Catalysis of the reaction: pinocarveol = carveol.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0715|EC:5.5.1.-									molecular_function											owl:Class	
GO:0009039	biolink:NamedThing	urease activity	Catalysis of the reaction: urea + H2O = CO2 + 2 NH3.	tmpzr1t_l9r_go_relaxed.owl	urea amidohydrolase activity				RHEA:20557|UM-BBD_reactionID:r0120|MetaCyc:UREASE-RXN|EC:3.5.1.5									molecular_function											owl:Class	
GO:0140506	biolink:NamedThing	endoplasmic reticulum-autophagosome adaptor activity	The binding activity of a molecule that brings together an ER membrane and an autophagosome during reticulophagy.	tmpzr1t_l9r_go_relaxed.owl	autophagosome-ER anchor|ER- autophagosome anchor|autophagosome-endoplasmic reticulum anchor	https://github.com/geneontology/go-ontology/issues/19873						pg	2020-08-27T11:04:43Z					molecular_function											owl:Class	
GO:0061803	biolink:NamedThing	posterior cell cortex	The region that lies just beneath the plasma membrane in the part of a cell that is closest to the posterior as defined by the developing, or existing, anterior/posterior axis.	tmpzr1t_l9r_go_relaxed.owl								dph	2016-11-06T22:55:45Z					cellular_component											owl:Class	
GO:0062076	biolink:NamedThing	acyl-CoA delta5-desaturase activity	Catalysis of the reaction: acyl-CoA + reduced acceptor + O2 = delta5-acyl-CoA + acceptor + 2 H2O.	tmpzr1t_l9r_go_relaxed.owl	acyl-CoA delta(5)-desaturase activity|acyl-CoA D5-desaturase activity|acyl-CoA (8-3)-desaturase				EC:1.14.19.44|RHEA:46424			dph	2018-09-24T15:33:59Z					molecular_function											owl:Class	
GO:0008725	biolink:NamedThing	DNA-3-methyladenine glycosylase activity	Catalysis of the reaction: DNA containing 3-methyladenine + H2O = DNA with abasic site + 3-methyladenine. This reaction is the hydrolysis of DNA by cleavage of the N-C1' glycosidic bond between the damaged DNA 3-methyladenine and the deoxyribose sugar to remove the 3-methyladenine, leaving an abasic site.	tmpzr1t_l9r_go_relaxed.owl	DNA-3-methyladenine glycosylase I activity|deoxyribonucleate 3-methyladenine glycosidase I|DNA-3-methyladenine glycosidase I activity|alkylated-DNA glycohydrolase (releasing methyladenine and methylguanine)|DNA glycosidase I activity|3-methyladenine DNA glycosylase I				MetaCyc:3.2.2.20-RXN|EC:3.2.2.20|MetaCyc:3.2.2.21-RXN|EC:3.2.2.21									molecular_function											owl:Class	
GO:0032181	biolink:NamedThing	dinucleotide repeat insertion binding	Binding to a double-stranded DNA region containing a dinucleotide repeat insertion or a deletion resulting in unpaired dinucleotide repeats.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0019930	biolink:NamedThing	cis-14-hydroxy-10,13-dioxo-7-heptadecenoic acid peptidyl-aspartate ester biosynthetic process from peptidyl-aspartic acid	The modification of peptidyl-aspartic acid to form peptidyl-cis-14-hydroxy-10,13-dioxo-7-heptadecenoic acid aspartate ester, typical of the barley lipid transfer protein 1.	tmpzr1t_l9r_go_relaxed.owl	cis-14-hydroxy-10,13-dioxo-7-heptadecenoic acid peptidyl-aspartate ester synthesis from peptidyl-aspartic acid|cis-14-hydroxy-10,13-dioxo-7-heptadecenoic acid peptidyl-aspartate ester anabolism from peptidyl-aspartic acid|cis-14-hydroxy-10,13-dioxo-7-heptadecenoic acid peptidyl-aspartate ester formation from peptidyl-aspartic acid				RESID:AA0316									biological_process											owl:Class	
GO:0042696	biolink:NamedThing	menarche	The beginning of the menstrual cycle; the first menstrual cycle in an individual.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Menarche	Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase. To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).								biological_process											owl:Class	
GO:0050204	biolink:NamedThing	oxalomalate lyase activity	Catalysis of the reaction: 3-oxalomalate = glyoxylate + oxaloacetate.	tmpzr1t_l9r_go_relaxed.owl	3-oxalomalate glyoxylate-lyase activity|3-oxalomalate glyoxylate-lyase (oxaloacetate-forming)				MetaCyc:OXALOMALATE-LYASE-RXN|EC:4.1.3.13|RHEA:22032|KEGG_REACTION:R00477									molecular_function											owl:Class	
GO:0016457	biolink:NamedThing	dosage compensation complex assembly involved in dosage compensation by hyperactivation of X chromosome	The aggregation, arrangement and bonding together of proteins on DNA to form the complex that mediates dosage compensation on the X chromosome of the heterogametic sex, ultimately resulting in a two-fold increase in transcription from this chromosome. An example of this is found in Drosophila melanogaster.	tmpzr1t_l9r_go_relaxed.owl	dosage compensation complex assembly during dosage compensation by hyperactivation of X chromosome													biological_process											owl:Class	
GO:0018580	biolink:NamedThing	nitronate monooxygenase activity	Catalysis of the reaction: ethylnitronate + O(2) = acetaldehyde + nitrite.	tmpzr1t_l9r_go_relaxed.owl	nitronate:oxygen 2-oxidoreductase (nitrite-forming) activity|2-nitropropane dioxygenase activity				EC:1.13.12.16|MetaCyc:2-NITROPROPANE-DIOXYGENASE-RXN|RHEA:28767	Where non-covalently bound FMN is used as the cofactor, see instead 'nitronate monooxygenase (FMN-linked) activity ; GO:0036434'.								molecular_function											owl:Class	
GO:0034869	biolink:NamedThing	2,4,4-trimethyl-3-oxopentanoyl-CoA thioesterase activity	Catalysis of the reaction: 2,4,4-trimethyl-3-oxopentanoyl-CoA + OH- = 2,4,4-trimethyl-3-oxopentanoate + CoASH.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r1307									molecular_function											owl:Class	
GO:0102319	biolink:NamedThing	2-deoxystreptamine N-acetyl-D-glucosaminyltransferase activity	Catalysis of the reaction: 2-deoxystreptamine(2+) + UDP-N-acetyl-alpha-D-glucosamine <=> H+ + 2'-N-acetylparomamine(2+) + UDP(3-).	tmpzr1t_l9r_go_relaxed.owl					EC:2.4.1.283|MetaCyc:RXN-13122|RHEA:33947									molecular_function											owl:Class	
GO:0052868	biolink:NamedThing	protein-lysine lysyltransferase activity	Catalysis of the reaction: protein-lysine + protein-lysine = protein N6-(lysyl)-L-lysine + protein. This reaction is the addition of lysine group from one protein to a lysine residue in a second protein, producing N6-(lysyl)-L-lysine.	tmpzr1t_l9r_go_relaxed.owl								ai	2012-01-11T03:05:27Z					molecular_function											owl:Class	
GO:0043757	biolink:NamedThing	adenosylcobinamide-phosphate synthase activity	Catalysis of the reactions: ATP + adenosylcobyric acid + (R)-1-aminopropan-2-yl phosphate = ADP + phosphate + adenosylcobinamide phosphate, and ATP + adenosylcobyric acid + (R)-1-aminopropan-2-ol = ADP + phosphate + adenosylcobinamide.	tmpzr1t_l9r_go_relaxed.owl	AdoCbi-P synthase activity|CbiB|adenosylcobyric acid:(R)-1-aminopropan-2-yl phosphate ligase (ADP-forming)				RHEA:21896|MetaCyc:RXN-6261|EC:6.3.1.10									molecular_function											owl:Class	
GO:0046178	biolink:NamedThing	D-gluconate biosynthetic process	The chemical reactions and pathways resulting in the formation of D-gluconate, the anion of D-gluconic acid, the aldonic acid derived from glucose.	tmpzr1t_l9r_go_relaxed.owl	D-gluconate synthesis|D-gluconate anabolism|D-gluconate formation|D-gluconate biosynthesis													biological_process											owl:Class	
GO:0019521	biolink:NamedThing	D-gluconate metabolic process	The chemical reactions and pathways involving D-gluconate, the anion of D-gluconic acid, the aldonic acid derived from glucose.	tmpzr1t_l9r_go_relaxed.owl	D-gluconate metabolism													biological_process											owl:Class	
GO:0051680	biolink:NamedThing	6-alpha-maltosylglucose biosynthetic process	The chemical reactions and pathways resulting in the formation of 6-alpha-maltosylglucose, also known as isopanose.	tmpzr1t_l9r_go_relaxed.owl	isopanose biosynthetic process|isopanose biosynthesis													biological_process											owl:Class	
GO:1990828	biolink:NamedThing	hepatocyte dedifferentiation	The process in which a hepatocyte (specialized epithelial cell of the liver) loses the structural or functional features that characterize it in the mature organism, or some other relatively stable phase of the organism's life history. Under certain conditions, these cells can revert back to the features of the stem cells that were their ancestors.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-08-20T14:14:57Z					biological_process											owl:Class	
GO:0033419	biolink:NamedThing	CUA codon-amino acid adaptor activity	A triplet codon-amino acid adaptor activity that recognizes a CUA codon.	tmpzr1t_l9r_go_relaxed.owl	CTA codon-amino acid adaptor activity|leucine tRNA					Note that in the standard genetic code, CTA codes for leucine.								molecular_function											owl:Class	
GO:0018808	biolink:NamedThing	trans-4-(1'-hydroxynaphth-2'-yl)-2-oxobut-3-enoate hydratase-aldolase activity	Catalysis of the reaction: trans-4-(1'-hydroxynaphth-2'-yl)-2-oxobut-3-enoate + H2O = pyruvate + 1-hydroxy-2-naphthaldehyde.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0484									molecular_function											owl:Class	
GO:0046026	biolink:NamedThing	precorrin-4 C11-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + precorrin-4 = S-adenosyl-L-homocysteine + precorrin 5.	tmpzr1t_l9r_go_relaxed.owl	CobM|S-adenosyl-L-methionine:precorrin-4 C11 methyltransferase activity				EC:2.1.1.133|MetaCyc:2.1.1.133-RXN|RHEA:22012									molecular_function											owl:Class	
GO:1990723	biolink:NamedThing	cytoplasmic periphery of the nuclear pore complex	Cytoplasm situated in close proximity to a nuclear pore complex.	tmpzr1t_l9r_go_relaxed.owl	associated with the nuclear pore	https://github.com/geneontology/go-ontology/issues/21774						sl	2015-04-06T19:26:54Z					cellular_component											owl:Class	
GO:0062096	biolink:NamedThing	kinetochore disassembly	The disaggregation of a kinetochore into its constituent components.	tmpzr1t_l9r_go_relaxed.owl								dph	2018-11-26T16:34:55Z					biological_process											owl:Class	
GO:0051383	biolink:NamedThing	kinetochore organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the kinetochore, a multisubunit complex that is located at the centromeric region of DNA and provides an attachment point for the spindle microtubules.	tmpzr1t_l9r_go_relaxed.owl	kinetochore organisation|kinetochore organization and biogenesis													biological_process											owl:Class	
GO:1990326	biolink:NamedThing	collagen type XXVIII trimer	A collagen homotrimer of alpha1(XXVIII) chains.	tmpzr1t_l9r_go_relaxed.owl								bhm	2014-03-16T23:15:28Z					cellular_component											owl:Class	
GO:0061652	biolink:NamedThing	FAT10 conjugating enzyme activity	Isoenergetic transfer of FAT10 from one protein to another via the reaction X-FAT10 + Y -> Y-FAT10 + X, where both the X-FAT10 and Y-FAT10 linkages are thioester bonds between the C-terminal amino acid of FAT10 and a sulfhydryl side group of a cysteine residue.	tmpzr1t_l9r_go_relaxed.owl	E2							dph	2014-11-06T13:21:50Z					molecular_function											owl:Class	
GO:0050373	biolink:NamedThing	UDP-arabinose 4-epimerase activity	Catalysis of the reaction: UDP-L-arabinose = UDP-alpha-D-xylose.	tmpzr1t_l9r_go_relaxed.owl	UDP-D-xylose 4-epimerase activity|UDP-D-xylose-4-epimerase activity|UDP-L-arabinose 4-epimerase activity|uridine diphosphoarabinose epimerase activity|UDParabinose 4-epimerase activity|uridine 5'-diphosphate-D-xylose 4-epimerase activity|UDP arabinose epimerase activity				RHEA:11320|KEGG_REACTION:R01473|MetaCyc:UDP-ARABINOSE-4-EPIMERASE-RXN|EC:5.1.3.5									molecular_function											owl:Class	
GO:0120199	biolink:NamedThing	cone photoreceptor outer segment	The outer segment of a vertebrate cone photoreceptor that contains membrane discs that are contiguous with the ciliary membrane and containing opsin photoreceptor proteins.	tmpzr1t_l9r_go_relaxed.owl								krc	2019-05-07T22:23:28Z					cellular_component											owl:Class	
GO:0071069	biolink:NamedThing	alpha4-beta1 integrin-thrombospondin-1 complex	A protein complex that consists of an alpha4-beta1 integrin complex bound to thrombospondin-1.	tmpzr1t_l9r_go_relaxed.owl	ITGA4-ITGB1-THBS1 complex							mah	2009-11-03T04:05:35Z					cellular_component											owl:Class	
GO:0016913	biolink:NamedThing	follicle-stimulating hormone activity	The action characteristic of follicle-stimulating hormone (FSH), a gonadotrophic glycoprotein hormone secreted, in mammals, by the anterior pituitary gland. Upon receptor binding, FSH stimulates growth of Graafian follicles in the ovaries in females, and stimulates the epithelium of the seminiferous tubules to increase spermatogenesis.	tmpzr1t_l9r_go_relaxed.owl	FSH activity|follicle stimulating hormone activity|follitropin activity													molecular_function											owl:Class	
GO:0008661	biolink:NamedThing	1-deoxy-D-xylulose-5-phosphate synthase activity	Catalysis of the reaction: D-glyceraldehyde 3-phosphate + H(+) + pyruvate = 1-deoxy-D-xylulose 5-phosphate + CO(2).	tmpzr1t_l9r_go_relaxed.owl	1-deoxyxylulose-5-phosphate synthase activity|DXP-synthase activity|pyruvate:D-glyceraldehyde-3-phosphate acetaldehydetransferase (decarboxylating)|DOXP synthase activity|1-deoxy-D-xylulose-5-phosphate pyruvate-lyase (carboxylating) activity				RHEA:12605|KEGG_REACTION:R05636|EC:2.2.1.7|MetaCyc:DXS-RXN									molecular_function											owl:Class	
GO:0047363	biolink:NamedThing	triglucosylalkylacylglycerol sulfotransferase activity	Catalysis of the reaction: alpha-D-glucosyl-1,6-alpha-D-glucosyl-1,6-alpha-D-glucosyl-1,3-1-O-alkyl-2-O-acylglycerol + 3'-phosphoadenosine 5'-phosphosulfate = 6-sulfo-alpha-D-glucosyl-1,6-alpha-D-glucosyl-1,6-alpha-D-glucosyl-1,3-1-O-alkyl-2-O-acylglycerol + adenosine 3',5'-bisphosphate.	tmpzr1t_l9r_go_relaxed.owl	triglucosylalkylacylglycerol sulphotransferase activity|3'-phosphoadenylyl-sulfate:triglucosyl-1-O-alkyl-2-O-acylglycerol 6-sulfotransferase activity|triglucosylmonoalkylmonoacyl sulfotransferase activity				RHEA:13273|MetaCyc:2.8.2.19-RXN|EC:2.8.2.19									molecular_function											owl:Class	
GO:0031770	biolink:NamedThing	growth hormone-releasing hormone receptor binding	Binding to a growth hormone-releasing hormone receptor.	tmpzr1t_l9r_go_relaxed.owl	growth hormone-releasing hormone receptor ligand													molecular_function											owl:Class	
GO:1902966	biolink:NamedThing	positive regulation of protein localization to early endosome	Any process that activates or increases the frequency, rate or extent of protein localization to early endosome.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of protein localisation in early endosome|activation of protein localisation to early endosome|up-regulation of protein localization in early endosome|up-regulation of protein localization to early endosome|up regulation of protein localisation to early endosome|upregulation of protein localization to early endosome|upregulation of protein localisation to early endosome|up regulation of protein localisation in early endosome|activation of protein localization in early endosome|activation of protein localisation in early endosome|up regulation of protein localization to early endosome|up regulation of protein localization in early endosome|up-regulation of protein localisation to early endosome|positive regulation of protein localisation to early endosome|activation of protein localization to early endosome|upregulation of protein localisation in early endosome|upregulation of protein localization in early endosome|positive regulation of protein localization in early endosome|up-regulation of protein localisation in early endosome							sjp	2014-05-06T09:28:30Z					biological_process											owl:Class	
GO:0042712	biolink:NamedThing	paternal behavior	Male behaviors associated with the care and rearing offspring.	tmpzr1t_l9r_go_relaxed.owl	paternal behaviour													biological_process											owl:Class	
GO:0102203	biolink:NamedThing	brassicasterol glucosyltransferase activity	Catalysis of the reaction: UDP-alpha-D-glucose + brassicasterol <=> UDP(3-) + 3-O-beta-D-glucosyl-brassicasterol + H+.	tmpzr1t_l9r_go_relaxed.owl					EC:2.4.1.173|RHEA:61840|MetaCyc:RXN-12125									molecular_function											owl:Class	
GO:0102575	biolink:NamedThing	3-oxo-dodecanoyl-ACP hydrolase activity	Catalysis of the reaction: H2O + a 3-oxo-dodecanoyl-[acp] = 3-oxododecanoate + H+ + a holo-[acyl-carrier protein].	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-15281									molecular_function											owl:Class	
GO:1901982	biolink:NamedThing	maltose binding	Binding to maltose.	tmpzr1t_l9r_go_relaxed.owl								tb	2013-03-13T18:17:19Z					molecular_function											owl:Class	
GO:1990698	biolink:NamedThing	palmitoleoyltransferase activity	Catalysis of the transfer of a palmitoleyl group, a 16-carbon monounsaturated fatty acid (C16:1), to an acceptor molecule.	tmpzr1t_l9r_go_relaxed.owl								sp	2015-03-13T08:58:25Z					molecular_function											owl:Class	
GO:0098989	biolink:NamedThing	NMDA selective glutamate receptor signaling pathway	A series of molecular signals initiated by glutamate binding to an NMDA-selective glutamate receptor on the surface of the target cell, followed by the movement of ions through a channel in the receptor complex. Ends with regulation of a downstream cellular process, e.g. transcription.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0007451	biolink:NamedThing	dorsal/ventral lineage restriction, imaginal disc	Formation and/or maintenance of a lineage boundary between dorsal and ventral compartments that cells cannot cross, thus separating the populations of cells in each compartment.	tmpzr1t_l9r_go_relaxed.owl	dorsal-ventral lineage restriction, imaginal disc|dorsoventral lineage restriction, imaginal disc													biological_process											owl:Class	
GO:0010815	biolink:NamedThing	bradykinin catabolic process	The chemical reactions and pathways resulting in the breakdown of the peptide bradykinin.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0033110	biolink:NamedThing	Cvt vesicle membrane	Either of the two lipid bilayers surrounding a Cvt vesicle, a vesicle that functions in the cytoplasm-to-vacuole targeting (Cvt) pathway.	tmpzr1t_l9r_go_relaxed.owl	cytoplasm to vacuole targeting vesicle membrane|cytoplasm-to-vacuole targeting vesicle membrane													cellular_component											owl:Class	
GO:0050367	biolink:NamedThing	tyrosine-arginine ligase activity	Catalysis of the reaction: L-arginine + L-tyrosine + ATP = L-tyrosyl-L-arginine + AMP + diphosphate + 2 H(+).	tmpzr1t_l9r_go_relaxed.owl	L-tyrosine:L-arginine ligase (AMP-forming)|kyotorphin synthetase activity|tyrosyl-arginine synthase activity|kyotorphin-synthesizing enzyme activity|kyotorphin synthase activity				KEGG_REACTION:R00735|RHEA:15345|EC:6.3.2.24|MetaCyc:TYROSINE--ARGININE-LIGASE-RXN									molecular_function											owl:Class	
GO:0004400	biolink:NamedThing	histidinol-phosphate transaminase activity	Catalysis of the reaction: L-histidinol-phosphate + 2-oxoglutarate = 3-(imidazol-4-yl)-2-oxopropyl phosphate + L-glutamate.	tmpzr1t_l9r_go_relaxed.owl	L-histidinol-phosphate:2-oxoglutarate aminotransferase activity|IAP transaminase activity|histidinol-phosphate aminotransferase activity|L-histidinol phosphate aminotransferase activity|histidinol phosphate aminotransferase activity|glutamic-imidazoleacetol phosphate transaminase activity|histidine:imidazoleacetol phosphate transaminase activity|imidazoleacetol phosphate transaminase activity|imidazole acetol-phosphate transaminase activity|imidazolylacetolphosphate transaminase activity|imidazolylacetolphosphate aminotransferase activity				MetaCyc:HISTAMINOTRANS-RXN|RHEA:23744|EC:2.6.1.9									molecular_function											owl:Class	
GO:0039512	biolink:NamedThing	suppression by virus of host protein tyrosine kinase activity	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host protein tyrosine kinase activity.	tmpzr1t_l9r_go_relaxed.owl	negative regulation by virus of host protein tyrosine kinase activity|down-regulation by virus of host protein tyrosine kinase activity|inhibition by virus of host protein tyrosine kinase activity|downregulation by virus of host protein tyrosine kinase activity							bf	2011-06-16T02:27:26Z					biological_process											owl:Class	
GO:0015599	biolink:NamedThing	ATPase-coupled L-glutamine transmembrane transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + glutamine(out) -> ADP + phosphate + glutamine(in).	tmpzr1t_l9r_go_relaxed.owl	glutamine porter activity|ATPase-coupled glutamine transmembrane transporter activity|glutamine-importing ATPase activity				MetaCyc:ABC-12-RXN|EC:7.4.2.1									molecular_function											owl:Class	
GO:0035626	biolink:NamedThing	juvenile hormone mediated signaling pathway	A series of molecular signals initiated by the binding of juvenile hormone to a receptor, and ending with regulation of cell state or activity.	tmpzr1t_l9r_go_relaxed.owl	juvenile hormone mediated signalling pathway|juvenile hormone-mediated signaling pathway							bf	2010-12-08T04:45:25Z					biological_process											owl:Class	
GO:0036052	biolink:NamedThing	protein localization to uropod	A process in which a protein is transported to, or maintained in, a uropod. A uropod is a membrane projection with related cytoskeletal components at the trailing edge of a migrating cell.	tmpzr1t_l9r_go_relaxed.owl	protein localisation to uropod							bf	2011-12-12T10:45:26Z					biological_process											owl:Class	
GO:0004450	biolink:NamedThing	isocitrate dehydrogenase (NADP+) activity	Catalysis of the reaction: isocitrate + NADP+ = 2-oxoglutarate + CO2 + NADPH + H+.	tmpzr1t_l9r_go_relaxed.owl	isocitrate (nicotinamide adenine dinucleotide phosphate) dehydrogenase activity|isocitrate (NADP) dehydrogenase activity|NADP(+)-IDH activity|NADP(+)-linked isocitrate dehydrogenase activity|isocitrate:NADP+ oxidoreductase (decarboxylating)|triphosphopyridine nucleotide-linked isocitrate dehydrogenase activity|NADP-dependent isocitrate dehydrogenase activity|NADP-linked isocitrate dehydrogenase activity|NADP(+)-ICDH activity|NADP isocitric dehydrogenase activity|NADP-specific isocitrate dehydrogenase activity|isocitrate dehydrogenase (NADP-dependent) activity|isocitrate dehydrogenase (NADP) activity|NADP-dependent isocitric dehydrogenase activity|dual-cofactor-specific isocitrate dehydrogenase activity				Reactome:R-HSA-450984|EC:1.1.1.42|Reactome:R-HSA-389540|RHEA:19629|MetaCyc:ISOCITDEH-RXN|Reactome:R-HSA-389550									molecular_function											owl:Class	
GO:1905640	biolink:NamedThing	response to acetaldehyde	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acetaldehyde stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2016-11-04T15:07:18Z					biological_process											owl:Class	
GO:1990875	biolink:NamedThing	nucleoplasmic side of nuclear pore	The side of the nuclear pore complex (NPC) that faces the nucleoplasm.	tmpzr1t_l9r_go_relaxed.owl	nucleoplasmic side of nuclear pore complex|nucleoplasmic side of NPC|nucleoplasmic side of nucleopore							sl	2015-10-01T21:32:22Z					cellular_component											owl:Class	
GO:0004030	biolink:NamedThing	aldehyde dehydrogenase [NAD(P)+] activity	Catalysis of the reaction: an aldehyde + NAD(P)+ + H2O = an acid + NAD(P)H + H+.	tmpzr1t_l9r_go_relaxed.owl	aldehyde:NAD(P)+ oxidoreductase activity|ALDH				EC:1.2.1.5|Reactome:R-HSA-5696080|Reactome:R-HSA-5692283|Reactome:R-HSA-6808464|MetaCyc:ALDEHYDE-DEHYDROGENASE-NADP+-RXN									molecular_function											owl:Class	
GO:0060320	biolink:NamedThing	rejection of self pollen	The process, involving the sharing and interaction of the single locus incompatibility haplotypes, involved in the rejection of the self pollen by cells in the stigma.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0150052	biolink:NamedThing	regulation of postsynapse assembly	Any process that modulates the frequency, rate or extent of postsynapse assembly, the aggregation, arrangement and bonding together of a set of components to form a postsynapse.	tmpzr1t_l9r_go_relaxed.owl								bc	2018-05-08T16:38:55Z					biological_process											owl:Class	
GO:0034847	biolink:NamedThing	naphthyl-2-hydroxymethyl-succinyl-CoA dehydrogenase activity	Catalysis of the reaction: naphthyl-2-hydroxymethyl-succinyl-CoA = naphthyl-2-oxomethyl-succinyl-CoA + 2 H+ + 2 e-.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r1260									molecular_function											owl:Class	
GO:0034881	biolink:NamedThing	citrazinate hydrolase activity	Catalysis of the reaction: citrazinate + H2O = cis-aconitamide.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r1343									molecular_function											owl:Class	
GO:0047880	biolink:NamedThing	erythrulose reductase activity	Catalysis of the reaction: D-threitol + NADP(+) = D-erythrulose + H(+) + NADPH.	tmpzr1t_l9r_go_relaxed.owl	D-erythrulose reductase activity|erythritol:NADP+ oxidoreductase activity				RHEA:18005|EC:1.1.1.162|MetaCyc:ERYTHRULOSE-REDUCTASE-RXN|KEGG_REACTION:R08573									molecular_function											owl:Class	
GO:0035648	biolink:NamedThing	circadian mating behavior	The fluctuation in mating behavior that occurs over an approximately 24 hour cycle.	tmpzr1t_l9r_go_relaxed.owl	circadian mating behaviour|circadian mating rhythm							bf	2011-01-25T10:20:05Z					biological_process											owl:Class	
GO:0102092	biolink:NamedThing	5-diphosphoinositol pentakisphosphate 3-kinase activity	Catalysis of the reaction: 5-diphospho-1D-myo-inositol pentakisphosphate + ATP = 3,5-bisdiphosphoinositol-1D-myo-inositol 2,3,4,6-tetrakisphosphate + ADP.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-10979|EC:2.7.4.24									molecular_function											owl:Class	
GO:0102587	biolink:NamedThing	cyanidin 3-O-[2''-O-(2''-O-(sinapoyl) xylosyl) 6''-O-(p-O-(glucosyl)-p-coumaroyl) glucoside] 5-O-[6''-O-(malonyl) glucoside] sinapoylglucose glucosyltransferase activity	Catalysis of the reaction: cyanidin 3-O-[2''-O-(2'''-O-(sinapoyl) xylosyl) 6''-O-(p-coumaroyl) glucoside] 5-O-[6''-O-(malonyl) glucoside + 1-O-sinapoyl-beta-D-glucose <=> cyanidin 3-O-[6-O-(4-O-beta-D-glucosyl-p-coumaroyl)-2-O-(2-O-sinapoyl-beta-D-xylosyl)-beta-D-glucosyl]-5-O-(6-O-malonyl-beta-D-glucoside) + trans-sinapate + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-15333									molecular_function											owl:Class	
GO:0140334	biolink:NamedThing	lipopolysaccharide localization to cell outer membrane	A process in which a lipopolysaccharide is transported to the cell outer membrane.	tmpzr1t_l9r_go_relaxed.owl	LPS localization to cell outer membrane							pg	2019-05-13T12:23:36Z					biological_process											owl:Class	
GO:0090618	biolink:NamedThing	DNA clamp unloading	The process of removing the PCNA complex from DNA when Okazaki fragments are completed or the replication fork terminates.	tmpzr1t_l9r_go_relaxed.owl	PCNA unloading							tb	2014-10-29T12:57:05Z					biological_process											owl:Class	
GO:0047581	biolink:NamedThing	4-methyleneglutamate-ammonia ligase activity	Catalysis of the reaction: 4-methylene-L-glutamate + ATP + NH(4)(+) = 4-methylene-L-glutamine + AMP + diphosphate + 2 H(+).	tmpzr1t_l9r_go_relaxed.owl	4-methyleneglutamine synthetase activity|4-methylene-L-glutamate:ammonia ligase (AMP-forming)				MetaCyc:4-METHYLENEGLUTAMATE--AMMONIA-LIGASE-RXN|RHEA:13853|KEGG_REACTION:R02711|EC:6.3.1.7									molecular_function											owl:Class	
GO:0071289	biolink:NamedThing	cellular response to nickel ion	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nickel ion stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to nickel							mah	2009-12-10T04:07:31Z					biological_process											owl:Class	
GO:0050634	biolink:NamedThing	phloroisovalerophenone synthase activity	Catalysis of the reaction: isovaleryl-CoA + 3 malonyl-CoA = 4 CoASH + 3 CO2 + 3-methyl-1-(2,4,6-trihydroxyphenyl)butan-1-one.	tmpzr1t_l9r_go_relaxed.owl	isovaleryl-CoA:malonyl-CoA acyltransferase activity|valerophenone synthase activity|3-methyl-1-(trihydroxyphenyl)butan-1-one synthase activity				RHEA:23572|EC:2.3.1.156|MetaCyc:2.3.1.156-RXN									molecular_function											owl:Class	
GO:0044081	biolink:NamedThing	modulation by symbiont of host nitric oxide-mediated signal transduction	Any process in which a symbiont organism modulates the rate, frequency or extent of nitric oxide mediated signal transduction in its host organism. Nitric oxide mediated signal transduction is a series of molecular signals mediated by the detection of nitric oxide (NO).	tmpzr1t_l9r_go_relaxed.owl	modulation of host nitric oxide-mediated signal transduction by symbiont|modulation of host nitric oxide-mediated signaling by symbiont|modulation of host nitric oxide-mediated signalling by symbiont|modulation by symbiont of host nitric oxide mediated signal transduction|regulation by symbiont of host nitric oxide-mediated signal transduction													biological_process											owl:Class	
GO:0034669	biolink:NamedThing	integrin alpha4-beta7 complex	An integrin complex that comprises one alpha4 subunit and one beta7 subunit.	tmpzr1t_l9r_go_relaxed.owl	alpha4-beta7 integrin complex|ITGA4-ITGB7 complex													cellular_component											owl:Class	
GO:0047001	biolink:NamedThing	2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase activity	Catalysis of the reaction: NAD+ + 2-dehydro-3-deoxy-D-gluconate = NADH + (4S)-4,6-dihydroxy-2,5-dioxohexanoate.	tmpzr1t_l9r_go_relaxed.owl	2-keto-3-deoxy-D-gluconate (3-deoxy-D-glycero-2,5-hexodiulosonic acid) dehydrogenase activity|2-keto-3-deoxygluconate dehydrogenase activity|2-dehydro-3-deoxy-D-gluconate:NAD+ 5-oxidoreductase activity|2-keto-3-deoxygluconate 5-dehydrogenase activity|2-keto-3-deoxygluconate (nicotinamide adenine dinucleotide (phosphate)) dehydrogenase activity				EC:1.1.1.127|MetaCyc:1.1.1.127-RXN|RHEA:24232									molecular_function											owl:Class	
GO:0047049	biolink:NamedThing	(R)-2-hydroxy-fatty acid dehydrogenase activity	Catalysis of the reaction: (R)-2-hydroxystearate + NAD(+) = 2-oxostearate + H(+) + NADH.	tmpzr1t_l9r_go_relaxed.owl	(R)-2-hydroxystearate:NAD+ oxidoreductase activity|(R)-2-hydroxy-fatty-acid dehydrogenase activity|D-2-hydroxy fatty acid dehydrogenase activity|2-hydroxy fatty acid oxidase				RHEA:15949|KEGG_REACTION:R03021|EC:1.1.1.98|MetaCyc:1.1.1.98-RXN									molecular_function											owl:Class	
GO:0047122	biolink:NamedThing	quinaldate 4-oxidoreductase activity	Catalysis of the reaction: A + H(2)O + quinaldate = AH(2) + kynurenate.	tmpzr1t_l9r_go_relaxed.owl	quinoline-2-carboxylate:acceptor 4-oxidoreductase (hydroxylating)|quinaldic acid 4-oxidoreductase activity				EC:1.3.99.18|MetaCyc:1.3.99.18-RXN|KEGG_REACTION:R03687|RHEA:16697									molecular_function											owl:Class	
GO:0052624	biolink:NamedThing	2-phytyl-1,4-naphthoquinone methyltransferase activity	Catalysis of the reaction: demethylphylloquinone + S-adenosyl-L-methionine = phylloquinone + S-adenosyl-L-homocysteine + H+.	tmpzr1t_l9r_go_relaxed.owl	S-adenosyl-L-methionine:2-phytyl-1,4-naphthoquinone methyltransferase activity|SA methyltransferase activity|S-adenosyl-L-methionine:demethylphylloquinone methyltransferase activity|demethylphylloquinone methyltransferase activity|salicylic acid methyltransferase activity|S-adenosyl-L-methionine:salicylate carboxyl methyltransferase activity|salicylate methyltransferase activity				MetaCyc:RXN-7569|KEGG_REACTION:R06859|MetaCyc:RXN-6723			ai	2010-08-26T12:00:06Z					molecular_function											owl:Class	
GO:0004805	biolink:NamedThing	trehalose-phosphatase activity	Catalysis of the reaction: trehalose 6-phosphate + H2O = trehalose + phosphate.	tmpzr1t_l9r_go_relaxed.owl	trehalose 6-phosphate phosphatase activity|trehalose 6-phosphatase activity|trehalose-6-phosphate phosphohydrolase activity|trehalose phosphatase activity				EC:3.1.3.12|MetaCyc:TREHALOSEPHOSPHA-RXN|RHEA:23420									molecular_function											owl:Class	
GO:0018767	biolink:NamedThing	2-hydroxy-6-oxo-7-methylocta-2,4-dienoate hydrolase activity	Catalysis of the reaction: 2-hydroxy-6-oxo-7-methylocta-2,4-dienoate + H2O = cis-2-hydroxypenta-2,4-dienoate + isobutyrate.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0399									molecular_function											owl:Class	
GO:1990841	biolink:NamedThing	promoter-specific chromatin binding	Binding to a section of chromatin that is associated with gene promoter sequences of DNA.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-08-28T14:48:29Z					molecular_function											owl:Class	
GO:0031694	biolink:NamedThing	alpha-2A adrenergic receptor binding	Binding to an alpha-2A adrenergic receptor.	tmpzr1t_l9r_go_relaxed.owl	alpha-2A adrenergic receptor ligand													molecular_function											owl:Class	
GO:0102635	biolink:NamedThing	11-deoxycorticosterone reductase activity	Catalysis of the reaction: 11-deoxycorticosterone + NADH + H+ <=> 4-pregnen-20,21-diol-3-one + NAD.	tmpzr1t_l9r_go_relaxed.owl					RHEA:47716|MetaCyc:RXN-15607									molecular_function											owl:Class	
GO:0008481	biolink:NamedThing	sphinganine kinase activity	Catalysis of the reaction: ATP + sphinganine = ADP + sphinganine 1-phosphate.	tmpzr1t_l9r_go_relaxed.owl	sphingosine kinase activity|sphingosine kinase (phosphorylating)|ATP:sphinganine 1-phosphotransferase activity|dihydrosphingosine kinase (phosphorylating)|dihydrosphingosine kinase activity				MetaCyc:SPHINGANINE-KINASE-RXN|RHEA:15465|Reactome:R-HSA-428214|EC:2.7.1.91							GO:0001728		molecular_function											owl:Class	
GO:0052001	biolink:NamedThing	type IV pili-dependent localized adherence to host	Attachment of bacterial clusters to the surface of the host in a type IV pili dependent manner. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0052737	biolink:NamedThing	pyruvate dehydrogenase (quinone) activity	Catalysis of the reaction: a ubiquinone + H2O + pyruvate = a ubiquinol + acetate + CO2.	tmpzr1t_l9r_go_relaxed.owl	pyruvate dehydrogenase activity|pyruvate:ubiquinone oxidoreductase activity|pyruvate:ubiquinone-8-oxidoreductase activity|pyruvic dehydrogenase activity				MetaCyc:RXN-11496|RHEA:27405|KEGG_REACTION:R03145|EC:1.2.5.1									molecular_function											owl:Class	
GO:0052738	biolink:NamedThing	oxidoreductase activity, acting on the aldehyde or oxo group of donors, with a quinone or similar compound as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which an aldehyde or ketone (oxo) group acts as a hydrogen or electron donor and reduces a quinone or similar compound.	tmpzr1t_l9r_go_relaxed.owl					EC:1.2.5.-									molecular_function											owl:Class	
GO:0031837	biolink:NamedThing	substance K receptor binding	Binding to a substance K receptor.	tmpzr1t_l9r_go_relaxed.owl	neurokinin-A receptor binding|substance K receptor ligand													molecular_function											owl:Class	
GO:0031834	biolink:NamedThing	neurokinin receptor binding	Binding to a neurokinin receptor.	tmpzr1t_l9r_go_relaxed.owl	neurokinin receptor ligand													molecular_function											owl:Class	
GO:0071603	biolink:NamedThing	endothelial cell-cell adhesion	The attachment of an endothelial cell to another endothelial cell via adhesion molecules.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-02-04T05:21:30Z					biological_process											owl:Class	
GO:0097362	biolink:NamedThing	MCM8-MCM9 complex	A hexameric protein complex composed of MCM8 and MCM9 and involved in homologous recombination repair following DNA interstrand cross-links.	tmpzr1t_l9r_go_relaxed.owl								pr	2012-07-20T02:10:12Z					cellular_component											owl:Class	
GO:0035362	biolink:NamedThing	protein-DNA ISRE complex assembly	The aggregation, arrangement and bonding together of proteins and DNA molecules to form a protein-DNA complex, in which the complex is formed through interaction of the protein(s) with a interferon-stimulated response element (ISRE) in the DNA.	tmpzr1t_l9r_go_relaxed.owl	protein-DNA interferon-stimulated response element complex assembly							bf	2010-03-10T10:40:09Z					biological_process											owl:Class	
GO:0017178	biolink:NamedThing	diphthine-ammonia ligase activity	Catalysis of the reaction: ATP + diphthine + NH(4)(+) = ADP + diphthamide + H(+) + phosphate.	tmpzr1t_l9r_go_relaxed.owl	diphthamide synthetase activity|diphthamide synthase activity|diphthine:ammonia ligase (ADP-forming)				KEGG_REACTION:R03613|RHEA:19753|Reactome:R-HSA-5358475|EC:6.3.1.14|MetaCyc:DIPHTINE--AMMONIA-LIGASE-RXN									molecular_function											owl:Class	
GO:0034914	biolink:NamedThing	trinitrophenol hydride denitratase activity	Catalysis of the reaction: trinitrophenol hydride Meisenheimer complex = 2,4-dinitrophenol + nitrite. Trinitrophenol is also known as TNP.	tmpzr1t_l9r_go_relaxed.owl	TNP hydride denitratase activity|2,4,6-trinitrophenol hydride denitratase activity				EC:1.7.99.-|UM-BBD_reactionID:r1448									molecular_function											owl:Class	
GO:0044203	biolink:NamedThing	host cell nuclear lamina	The fibrous, electron-dense layer lying on the nucleoplasmic side of the inner membrane of a host cell nucleus, composed of lamin filaments.	tmpzr1t_l9r_go_relaxed.owl								jl	2009-10-21T11:11:56Z					cellular_component											owl:Class	
GO:0061260	biolink:NamedThing	mesonephric mesangial cell differentiation	The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesangial cells of the mesonephros as it progresses from its formation to the mature state.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-08-30T02:25:08Z					biological_process											owl:Class	
GO:0050383	biolink:NamedThing	uracil dehydrogenase activity	Catalysis of the reaction: uracil + acceptor = barbiturate + reduced acceptor.	tmpzr1t_l9r_go_relaxed.owl					EC:1.17.99.4|MetaCyc:URACIL-DEHYDROGENASE-RXN|RHEA:22752									molecular_function											owl:Class	
GO:0036150	biolink:NamedThing	phosphatidylserine acyl-chain remodeling	Remodeling the acyl chains of phosphatidylserine, through sequential deacylation and re-acylation reactions, to generate phosphatidylserine containing different types of fatty acid acyl chains.	tmpzr1t_l9r_go_relaxed.owl	phosphatidyl-L-serine acyl-chain remodeling							bf	2012-03-14T01:35:44Z					biological_process											owl:Class	
GO:0050992	biolink:NamedThing	dimethylallyl diphosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of dimethylallyl diphosphate.	tmpzr1t_l9r_go_relaxed.owl	DPP biosynthesis|dimethylallyl diphosphate anabolism|dimethylallyl diphosphate biosynthesis|dimethylallyl diphosphate formation|dimethylallyl diphosphate synthesis|DPP biosynthetic process|dimethylallyl pyrophosphate biosynthetic process|dimethylallyl pyrophosphate biosynthesis													biological_process											owl:Class	
GO:0004852	biolink:NamedThing	uroporphyrinogen-III synthase activity	Catalysis of the reaction: hydroxymethylbilane = H(2)O + uroporphyrinogen III.	tmpzr1t_l9r_go_relaxed.owl	uroporphyrinogen III cosynthase activity|URO-synthase activity|hydroxymethylbilane hydro-lyase (cyclizing; uroporphyrinogen-III-forming)|porphobilinogenase activity|uroporphyrinogen isomerase activity|uroporphyrinogen-III cosynthase activity|uroporphyrinogen-III cosynthetase activity|hydroxymethylbilane hydro-lyase (cyclizing) activity				RHEA:18965|Reactome:R-HSA-189488|MetaCyc:UROGENIIISYN-RXN|KEGG_REACTION:R03165|EC:4.2.1.75									molecular_function											owl:Class	
GO:0098824	biolink:NamedThing	peptidyl-cysteine sulfation	The sulfation of peptidyl-cysteine to form S-sulfo-L-cysteine.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0171									biological_process											owl:Class	
GO:0047904	biolink:NamedThing	fructose 5-dehydrogenase activity	Catalysis of the reaction: D-fructose + A = 5-dehydro-D-fructose + AH(2).	tmpzr1t_l9r_go_relaxed.owl	D-fructose:(acceptor) 5-oxidoreductase activity|D-fructose dehydrogenase activity|D-fructose:acceptor 5-oxidoreductase activity|fructose 5-dehydrogenase (acceptor)				KEGG_REACTION:R00873|MetaCyc:FRUCTOSE-5-DEHYDROGENASE-RXN|RHEA:22304|EC:1.1.99.11									molecular_function											owl:Class	
GO:0033481	biolink:NamedThing	galacturonate biosynthetic process	The chemical reactions and pathways resulting in the formation of galacturonate, the anion of galacturonic acid.	tmpzr1t_l9r_go_relaxed.owl	galacturonate anabolism|galacturonate formation|galacturonate biosynthesis|galacturonate synthesis													biological_process											owl:Class	
GO:0036350	biolink:NamedThing	mannose-specific flocculation	The non-sexual aggregation of single-celled organisms mediated by the binding of cell wall proteins on one cell to mannose residues on the other.	tmpzr1t_l9r_go_relaxed.owl	cell-cell adhesion involved in mannose-specific flocculation							bf	2012-09-19T10:57:34Z			GO:0098612		biological_process											owl:Class	
GO:0052774	biolink:NamedThing	glucosyl-N-acetylglucosamine glucosaminidase activity	Catalysis of the reaction: glucosyl-N-acetylglucosamine + H2O = glucosamine + N-acetylglucosamine.	tmpzr1t_l9r_go_relaxed.owl								ai	2011-10-03T12:01:05Z					molecular_function											owl:Class	
GO:0004070	biolink:NamedThing	aspartate carbamoyltransferase activity	Catalysis of the reaction: L-aspartate + carbamoyl phosphate = N-carbamoyl-L-aspartate + H(+) + phosphate.	tmpzr1t_l9r_go_relaxed.owl	aspartate transcarbamoylase activity|L-aspartate transcarbamoylase activity|aspartate transcarbamylase activity|carbamoylaspartotranskinase activity|ATCase activity|carbamoyl-phosphate:L-aspartate carbamoyltransferase activity|aspartate carbamyltransferase activity|aspartic carbamyltransferase activity|aspartic acid transcarbamoylase activity|carbamylaspartotranskinase activity|aspartic transcarbamylase activity|L-aspartate transcarbamylase activity				Reactome:R-HSA-73573|EC:2.1.3.2|RHEA:20013|KEGG_REACTION:R01397|MetaCyc:ASPCARBTRANS-RXN									molecular_function											owl:Class	
GO:0047871	biolink:NamedThing	disulfoglucosamine-6-sulfatase activity	Catalysis of the reaction: N(2),6-disulfo-D-glucosamine + H(2)O = N-sulfo-D-glucosamine + H(+) + sulfate.	tmpzr1t_l9r_go_relaxed.owl	6,N-disulfoglucosamine 6-O-sulfohydrolase activity|disulphoglucosamine-6-sulphatase activity|N,6-O-disulfo-D-glucosamine 6-sulfohydrolase activity|N-sulfoglucosamine-6-sulfatase activity				EC:3.1.6.11|MetaCyc:DISULFOGLUCOSAMINE-6-SULFATASE-RXN|KEGG_REACTION:R03216|RHEA:15517									molecular_function											owl:Class	
GO:0061799	biolink:NamedThing	cyclic pyranopterin monophosphate synthase activity	Catalysis of the reaction:  (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate = cyclic pyranopterin phosphate + diphosphate.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-17809|EC:4.6.1.17|RHEA:49580			dph	2016-10-06T14:36:56Z					molecular_function											owl:Class	
GO:0102944	biolink:NamedThing	medicagenate UDP-glucosyltransferase activity	Catalysis of the reaction: UDP-alpha-D-glucose(2-) + medicagenate <=> UDP(3-) + a medicagenate monoglucoside.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-9035									molecular_function											owl:Class	
GO:0001717	biolink:NamedThing	conversion of seryl-tRNAsec to selenocys-tRNAsec	The modification process that results in the conversion of serine, carried by a specialized tRNA(ser) (which can read a UGA anticodon), to selenocysteine.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0015272	biolink:NamedThing	ATP-activated inward rectifier potassium channel activity	Enables the transmembrane transfer of a potassium ion by an inwardly-rectifying voltage-gated channel, where the inward rectification is due to a voltage-dependent block of the channel pore by ATP. An inwardly rectifying current-voltage relation is one where at any given driving force the inward flow of K+ ions exceeds the outward flow for the opposite driving force.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-5683209									molecular_function											owl:Class	
GO:0140525	biolink:NamedThing	antipodal site	The pole of the kinetoplast associated with kinetoplast DNA replication. The antipodal sites flank the kinetoplast DNA disk and are positioned approximately 180 degrees apart. In Trypanosoma brucei and Crithidia fasciculata, minicircles are attached at antipodal sites and they contain enzymes that catalyse some of the later reactions in minicircle replication.	tmpzr1t_l9r_go_relaxed.owl	antipodal zone	https://github.com/geneontology/go-ontology/issues/20036						pg	2020-09-29T08:01:53Z					cellular_component											owl:Class	
GO:0110062	biolink:NamedThing	negative regulation of angiotensin-activated signaling pathway	Any process that stops, prevents, or reduces the frequency, rate or extent of the angiotensin-activated signaling pathway.	tmpzr1t_l9r_go_relaxed.owl								kmv	2017-10-26T17:42:17Z					biological_process											owl:Class	
GO:0061121	biolink:NamedThing	regulation of positive chemotaxis to cAMP by DIF-2	Any process that modulates the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of DIF-2. DIF-2 is a chlorinated alkylphenone.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-05-17T08:16:21Z					biological_process											owl:Class	
GO:0018937	biolink:NamedThing	nitroglycerin metabolic process	The chemical reactions and pathways involving nitroglycerin, a well-known nitrate ester and an important component of dynamite and other propellants. Toxic to algae, invertebrate, and vertebrates.	tmpzr1t_l9r_go_relaxed.owl	NG metabolic process|nitroglycerin metabolism|NG metabolism				MetaCyc:P201-PWY|UM-BBD_pathwayID:ng									biological_process											owl:Class	
GO:0051996	biolink:NamedThing	squalene synthase activity	Catalysis of the reaction: presqualene diphosphate + NADPH = squalene + NADP+ + diphosphate.	tmpzr1t_l9r_go_relaxed.owl	squalene synthetase activity				EC:2.5.1.21|MetaCyc:RXN66-281	Note that the two reactions performed by EC:2.5.1.21 are represented in GO by 'farnesyl-diphosphate farnesyltransferase activity ; GO:0004310' and 'squalene synthase activity ; GO:0051996'.		ai	2010-07-16T05:10:24Z					molecular_function											owl:Class	
GO:0046491	biolink:NamedThing	L-methylmalonyl-CoA metabolic process	The chemical reactions and pathways involving L-methylmalonyl-CoA, the L-enantiomer of 2-carboxypropanoyl-CoA. S-methylmalonyl-CoA is an intermediate in the beta oxidation of odd-numbered fatty acids in animals.	tmpzr1t_l9r_go_relaxed.owl	L-methylmalonyl-CoA metabolism													biological_process											owl:Class	
GO:0061812	biolink:NamedThing	cyclic ADP-ribose hydrolase	Catalysis of the reaction: cyclic ADP-ribose + H20 = ADP-ribose (ADPR).	tmpzr1t_l9r_go_relaxed.owl								dph	2016-11-11T13:32:43Z					molecular_function											owl:Class	
GO:1990112	biolink:NamedThing	RQC complex	A multiprotein complex that forms a stable complex with large ribosomal subunits (60S in eukaryotes and 50S in prokaryotes) containing stalled polypeptides and triggers their degradation (ribosomal quality control). In budding yeast, this complex includes Cdc48p, Rkr1p, Tae2p, Rqc1p, Npl4p and Ufd1p proteins.	tmpzr1t_l9r_go_relaxed.owl	ribosome quality control complex|ribosome-bound quality control complex							rb	2013-05-31T21:42:43Z					cellular_component											owl:Class	
GO:0098024	biolink:NamedThing	virus tail, fiber	The fibrous region of the virus tail used to scan, recognize and attach to the host cell.	tmpzr1t_l9r_go_relaxed.owl	bacteriophage tail fiber					For tailed bacteriophages, fibers typically bind to particular Lipopolysaccharide (LPS), polysaccharide or protein receptors on the cell surface.		bm	2012-07-19T14:14:50Z					cellular_component											owl:Class	
GO:0072671	biolink:NamedThing	mitochondria-associated ubiquitin-dependent protein catabolic process	The chemical reactions and pathways resulting in the breakdown of proteins transported from mitochondria and targeted to cytoplasmic proteasomes for degradation as a response to oxidative stress conditions.	tmpzr1t_l9r_go_relaxed.owl	mitochondrion-associated protein catabolic process|mitochondria-associated protein catabolic process|mitochondria-associated protein degradation|MAD							mah	2011-02-18T11:53:28Z					biological_process											owl:Class	
GO:0036026	biolink:NamedThing	protein C inhibitor-PLAT complex	A heterodimeric protein complex that contains protein C inhibitor (SERPINA5) and tissue-type plasminogen activator (PLAT); formation of the complex inhibits the serine protease activity of tissue-type plasminogen activator.	tmpzr1t_l9r_go_relaxed.owl	protein C inhibitor-tissue-type plasminogen activator complex|SERPINA5-PLAT complex|serpin A5-PLAT complex|plasma serine protease inhibitor-PLAT complex|protein C inhibitor-tPA complex|PCI-PLAT complex							bf	2011-10-19T01:30:56Z					cellular_component											owl:Class	
GO:0046027	biolink:NamedThing	phospholipid:diacylglycerol acyltransferase activity	Catalysis of the reaction: phospholipid + 1,2-diacylglycerol = lysophospholipid + triacylglycerol.	tmpzr1t_l9r_go_relaxed.owl	PDAT activity|phospholipid:1,2-diacyl-sn-glycerol O-acyltransferase activity				RHEA:14057|MetaCyc:2.3.1.158-RXN|EC:2.3.1.158									molecular_function											owl:Class	
GO:1990456	biolink:NamedThing	mitochondrion-endoplasmic reticulum membrane tethering	The attachment of a mitochondrion and an endoplasmic reticulum via molecular tethers that physically bridge their respective membranes and attach them to each other. The tethering may facilitate exchange of metabolites between the organelles.	tmpzr1t_l9r_go_relaxed.owl	mitochondrion-endoplasmic reticulum tethering|mitochondrion-endoplasmic reticulum attachment|mitochondrion-ER membrane tethering|mitochondrion-ER attachment|mitochondrion-ER tethering							mcc	2014-08-14T13:32:30Z					biological_process											owl:Class	
GO:0071177	biolink:NamedThing	MAML2-RBP-Jkappa-ICN3 complex	A protein complex that consists of the intracellular domain of Notch3 (ICN3), the DNA-binding transcription factor RBP-Jkappa, and the transcriptional coactivator Mastermind-like-2 (MAML2); the complex is involved in transcriptional activation in response to Notch-mediated signaling.	tmpzr1t_l9r_go_relaxed.owl	MAML2-RBP-Jkappa-Notch3 complex							mah	2009-11-23T02:48:56Z					cellular_component											owl:Class	
GO:0106117	biolink:NamedThing	acidocalcisome organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an acidocalcisome. An acidocalcisome is an electron-dense acidic membrane-bounded organelle which contains a matrix of pyrophosphate and polyphosphates with bound calcium and other cations.	tmpzr1t_l9r_go_relaxed.owl	volutin granule organization|acidocalcisome biogenesis|acidocalcisome organisation|metachromatic granule organization|polyphosphate vacuole organization|acidocalcisome organization and biogenesis							hjd	2018-04-19T17:18:01Z					biological_process											owl:Class	
GO:0008915	biolink:NamedThing	lipid-A-disaccharide synthase activity	Catalysis of the reaction: 2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate + UDP-2,3-bis(3-hydroxytetradecanoyl)-D-glucosamine = 2,3-bis(3-hydroxytetradecanoyl)-D-glucosaminyl-(1->6)-beta-D-2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate + H(+) + UDP.	tmpzr1t_l9r_go_relaxed.owl	UDP-2,3-bis(3-hydroxytetradecanoyl)glucosamine:2,3-bis-(3-hydroxytetradecanoyl)-beta-D-glucosaminyl-1-phosphate 2,3-bis(3-hydroxytetradecanoyl)-glucosaminyltransferase activity				KEGG_REACTION:R04606|EC:2.4.1.182|RHEA:22668|MetaCyc:LIPIDADISACCHARIDESYNTH-RXN									molecular_function											owl:Class	
GO:0032443	biolink:NamedThing	regulation of ergosterol biosynthetic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of ergosterol.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0070002	biolink:NamedThing	glutamic-type peptidase activity	Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a mechanism involving a glutamate/glutamine catalytic dyad.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0050266	biolink:NamedThing	rosmarinate synthase activity	Catalysis of the reaction: caffeoyl-CoA + 3-(3,4-dihydroxyphenyl)lactate = CoA + rosmarinate.	tmpzr1t_l9r_go_relaxed.owl	rosmarinic acid synthase activity|caffeoyl-coenzyme A:3,4-dihydroxyphenyllactic acid caffeoyltransferase activity|caffeoyl-CoA:3-(3,4-dihydroxyphenyl)lactate 2'-O-caffeoyl-transferase activity|4-coumaroyl-CoA:4-hydroxyphenyllactic acid 4-coumaroyl transferase activity				MetaCyc:ROSMARINATE-SYNTHASE-RXN|EC:2.3.1.140|RHEA:22344									molecular_function											owl:Class	
GO:0050509	biolink:NamedThing	N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity	Catalysis of the reaction: N-acetyl-alpha-D-glucosaminyl-(1,4)-beta-D-glucuronosyl-proteoglycan + UDP-alpha-D-glucuronate = beta-D-glucuronosyl-(1,4)-N-acetyl-alpha-D-glucosaminyl-(1,4)-beta-D-glucuronosyl-proteoglycan + UDP.	tmpzr1t_l9r_go_relaxed.owl	N-acetylglucosaminylproteoglycan beta-1,4-glucuronyltransferase activity|N-acetylglucosaminyl-proteoglycan 4-b-glucuronosyltransferase activity|UDP-alpha-D-glucuronate:N-acetyl-alpha-D-glucosaminyl-(1->4)-beta-D-glucuronosyl-proteoglycan 4-beta-glucuronosyltransferase activity|heparan glucuronyltransferase II activity				Reactome:R-HSA-3656257|MetaCyc:2.4.1.225-RXN|Reactome:R-HSA-9036285|EC:2.4.1.225|Reactome:R-HSA-2076392|RHEA:20908|Reactome:R-HSA-2022856|Reactome:R-HSA-3656267|Reactome:R-HSA-9036289									molecular_function											owl:Class	
GO:0031824	biolink:NamedThing	type 1E serotonin receptor binding	Binding to a type 1E serotonin receptor.	tmpzr1t_l9r_go_relaxed.owl	type 1E serotonin receptor ligand|5-hydroxytryptamine 1E receptor binding													molecular_function											owl:Class	
GO:0002111	biolink:NamedThing	BRCA2-BRAF35 complex	A heterodimeric complex of BRCA2 and BRAF35 (BRCA2-associated factor 35). The BRCA2-BRAF35 complex is often associated with condensed chromatin during mitosis.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0033265	biolink:NamedThing	choline binding	Binding to choline, the amine 2-hydroxy-N,N,N-trimethylethanaminium.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0039616	biolink:NamedThing	T=2 icosahedral viral capsid	The protein coat that surrounds the infective nucleic acid in some virus particles where the subunits (capsomeres) are arranged to form an icosahedron with T=2 symmetry. The T=2 capsid is composed of 12 pentameric dimers.	tmpzr1t_l9r_go_relaxed.owl					VZ:838	The T=2 symmetry is an non-official appellation; strictly speaking the capsid has a T=1 symmetry with each unit composed of a homodimer.		bf	2012-07-18T02:01:55Z					cellular_component											owl:Class	
GO:0090555	biolink:NamedThing	phosphatidylethanolamine flippase activity	Catalysis of the movement of phosphatidylethanolamine from the exoplasmic to the cytosolic leaftlet of a membrane, using energy from the hydrolysis of ATP.	tmpzr1t_l9r_go_relaxed.owl	ATPase-coupled phosphatidylethanolamine transporter activity|phosphatidylethanolamine flippase activity (exoplasmic to cytosolic leaftlet)|phosphatidylethanolamine-translocating ATPase activity|ATP-dependent phosphatidylethanolamine transporter activity				RHEA:66132	Nomenclature note. Flippases and floppases are ATP-dependent transbilayer lipid translocators. According to an extensively used, though not universal, nomenclature, they catalyze lipid transfer towards the inward monolayer (flippases) or towards the outward monolayer (floppases). Scramblases are ATP-independent, non-selective, inducing non-specific transbilayer movements across the membrane. The direction of the translocation should be taken into account for annotation (from the exoplasmic to the cytosolic leaftlet of a membrane).		tb	2013-10-24T16:07:20Z					molecular_function											owl:Class	
GO:1901471	biolink:NamedThing	positive regulation of syringal lignin catabolic process	Any process that activates or increases the frequency, rate or extent of syringal lignin catabolic process.	tmpzr1t_l9r_go_relaxed.owl	up regulation of syringal lignin catabolism|upregulation of syringal lignin catabolic process|activation of syringal lignin breakdown|up-regulation of S-lignin catabolic process|up regulation of S-lignin catabolic process|positive regulation of syringal lignin catabolism|activation of syringal lignin catabolism|up regulation of syringal lignin degradation|up-regulation of syringal lignin catabolic process|activation of syringal lignin degradation|activation of syringal lignin catabolic process|upregulation of syringal lignin catabolism|positive regulation of syringal lignin degradation|upregulation of syringal lignin degradation|up regulation of syringal lignin breakdown|up-regulation of syringal lignin breakdown|positive regulation of syringal lignin breakdown|upregulation of S-lignin catabolic process|activation of S-lignin catabolic process|up-regulation of syringal lignin catabolism|upregulation of syringal lignin breakdown|positive regulation of S-lignin catabolic process|up regulation of syringal lignin catabolic process|up-regulation of syringal lignin degradation							tt	2012-10-02T14:42:39Z					biological_process											owl:Class	
GO:0015381	biolink:NamedThing	high-affinity sulfate transmembrane transporter activity	Enables the secondary active high affinity transfer of sulfate from one side of a membrane to the other. Secondary active transport is the transfer of a solute across a membrane, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters. In high-affinity transport the transporter is able to bind thesolute even if it is only present at very low concentrations.	tmpzr1t_l9r_go_relaxed.owl	high affinity sulfate transmembrane transporter activity|high affinity sulphate permease activity|high affinity sulfate permease activity													molecular_function											owl:Class	
GO:0016163	biolink:NamedThing	nitrogenase activity	Catalysis of the reaction: 8 reduced ferredoxin + 8 H+ + N2 + 16 ATP + 16 H2O = 8 oxidized ferredoxin + 2 NH3 + 16 ADP + 16 phosphate.	tmpzr1t_l9r_go_relaxed.owl	iron-iron nitrogenase activity|vanadium-iron nitrogenase activity|molybdenum-iron nitrogenase activity|reduced ferredoxin:dinitrogen oxidoreductase (ATP-hydrolysing) activity				MetaCyc:NITROGENASE-RXN|RHEA:21448|EC:1.18.6.1|UM-BBD_enzymeID:e0395									molecular_function											owl:Class	
GO:0102373	biolink:NamedThing	uvaol dehydrogenase activity	Catalysis of the reaction: uvaol + NADPH + O2 + H+ <=> ursolic aldehyde + NADP + 2 H2O.	tmpzr1t_l9r_go_relaxed.owl					EC:1.14.14.126|MetaCyc:RXN-13501									molecular_function											owl:Class	
GO:0034536	biolink:NamedThing	2-hydroxy-8-methylchromene-2-carboxylate isomerase activity	Catalysis of the reaction: 2-hydroxy-8-methylchromene-2-carboxylate = 2-hydroxy-3-methylbenzalpyruvate.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0782|EC:5.3.99.-									molecular_function											owl:Class	
GO:0047280	biolink:NamedThing	nicotinamide phosphoribosyltransferase activity	Catalysis of the reaction: diphosphate + nicotinamide mononucleotide = 5-phospho-alpha-D-ribose 1-diphosphate + H(+) + nicotinamide.	tmpzr1t_l9r_go_relaxed.owl	NMN diphosphorylase activity|NMN pyrophosphorylase activity|nicotinamide mononucleotide pyrophosphorylase activity|nicotinamide mononucleotide synthetase activity|nicotinamide-nucleotide:diphosphate phospho-alpha-D-ribosyltransferase activity|NMN synthetase activity				Reactome:R-HSA-197250|EC:2.4.2.12|MetaCyc:2.4.2.12-RXN|RHEA:16149|KEGG_REACTION:R01271									molecular_function											owl:Class	
GO:0070516	biolink:NamedThing	CAK-ERCC2 complex	A protein complex formed by the association of the cyclin-dependent protein kinase activating kinase (CAK) holoenzyme complex with ERCC2.	tmpzr1t_l9r_go_relaxed.owl	cyclin-dependent protein kinase activating kinase holoenzyme-ERCC2 complex													cellular_component											owl:Class	
GO:1900829	biolink:NamedThing	D-tyrosine catabolic process	The chemical reactions and pathways resulting in the breakdown of D-tyrosine.	tmpzr1t_l9r_go_relaxed.owl	D-tyrosine catabolism|D-tyrosine breakdown|D-tyrosine degradation							se	2012-06-06T09:27:24Z					biological_process											owl:Class	
GO:0008984	biolink:NamedThing	protein-glutamate methylesterase activity	Catalysis of the reaction: protein L-glutamate O(5)-methyl ester + H2O = protein L-glutamate + methanol.	tmpzr1t_l9r_go_relaxed.owl	methyl-accepting chemotaxis protein methyl-esterase activity|chemotaxis-specific methylesterase activity|CheB methylesterase activity|protein-L-glutamate-O5-methyl-ester acylhydrolase activity|methylesterase CheB activity|protein-L-glutamate-5-O-methyl-ester acylhydrolase activity				RHEA:23236|RESID:AA0072|MetaCyc:MCPMETEST-RXN|EC:3.1.1.61									molecular_function											owl:Class	
GO:0052817	biolink:NamedThing	very long chain acyl-CoA hydrolase activity	Catalysis of the reaction: H2O + a very long chain acyl-CoA = a very long chain carboxylate + CoA. A very long chain has chain length greater than C18.	tmpzr1t_l9r_go_relaxed.owl	very long-chain acyl-thioester hydrolase activity|very long-chain hydrolase activity|very long-chain acyl coenzyme A hydrolase activity|very long-chain-acyl-CoA hydrolase activity							ai	2011-10-27T12:18:28Z					molecular_function											owl:Class	
GO:0052816	biolink:NamedThing	long-chain acyl-CoA hydrolase activity	Catalysis of the reaction: H2O + a long-chain acyl-CoA = a long-chain carboxylate + CoA. A long chain is a chain of greater than 12 carbons in length.	tmpzr1t_l9r_go_relaxed.owl	long-chain hydrolase activity|long-chain acyl coenzyme A hydrolase activity|long-chain-acyl-CoA hydrolase activity|long-chain acyl-thioester hydrolase activity							ai	2011-10-25T05:31:11Z					molecular_function											owl:Class	
GO:0038020	biolink:NamedThing	insulin receptor recycling	The process that results in the return of an insulin receptor to an active state at the plasma membrane. An active state is when the receptor is ready to receive an insulin signal. Internalized insulin receptors can be recycled to the plasma membrane or sorted to lysosomes for protein degradation.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-06-23T04:52:05Z					biological_process											owl:Class	
GO:0043034	biolink:NamedThing	costamere	Regular periodic sub membranous arrays of vinculin in skeletal and cardiac muscle cells, these arrays link Z-discs to the sarcolemma and are associated with links to extracellular matrix.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Costamere									cellular_component											owl:Class	
GO:0018471	biolink:NamedThing	4-chlorobenzaldehyde oxidase activity	Catalysis of the reaction: 4-chlorobenzaldehyde + 2 H2O = 4-chlorobenzoate + 2 H+ + 2 e-.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0447|EC:1.14.13.-									molecular_function											owl:Class	
GO:0046193	biolink:NamedThing	anaerobic phenol-containing compound catabolic process	The chemical reactions and pathways resulting in the breakdown of a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring, in the absence of oxygen.	tmpzr1t_l9r_go_relaxed.owl	anaerobic phenol-containing compound breakdown|anaerobic phenol-containing compound catabolism|anaerobic phenol-containing compound degradation													biological_process											owl:Class	
GO:0016412	biolink:NamedThing	serine O-acyltransferase activity	Catalysis of the transfer of an acyl group to an oxygen atom on the serine molecule.	tmpzr1t_l9r_go_relaxed.owl					EC:2.3.1.30									molecular_function											owl:Class	
GO:0006237	biolink:NamedThing	deoxycytidine salvage	Any process that generates deoxycytidine, 2-deoxyribosylcytosine, from derivatives of it, without de novo synthesis.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0043695	biolink:NamedThing	detection of pheromone	The series of events in which a pheromone stimulus is received by a cell and converted into a molecular signal.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0004496	biolink:NamedThing	mevalonate kinase activity	Catalysis of the reaction: (R)-mevalonate + ATP = (R)-5-phosphomevalonate + ADP + 2 H(+).	tmpzr1t_l9r_go_relaxed.owl	MVA kinase activity|mevalonic kinase activity|mevalonic acid kinase activity|ATP:mevalonate 5-phosphotransferase activity|mevalonate phosphokinase activity|ATP:(R)-mevalonate 5-phosphotransferase activity|mevalonate 5-phosphotransferase activity|mevalonate kinase (phosphorylating)				Reactome:R-HSA-191380|KEGG_REACTION:R02245|EC:2.7.1.36|MetaCyc:MEVALONATE-KINASE-RXN|RHEA:17065									molecular_function											owl:Class	
GO:0006478	biolink:NamedThing	peptidyl-tyrosine sulfation	The sulfation of peptidyl-tyrosine residues to form peptidyl-O4'-sulfo-L-tyrosine.	tmpzr1t_l9r_go_relaxed.owl	peptidyl-tyrosine sulphation				RESID:AA0172									biological_process											owl:Class	
GO:0046570	biolink:NamedThing	methylthioribulose 1-phosphate dehydratase activity	Catalysis of the reaction: S-methyl-5-thio-D-ribulose 1-phosphate = 5-(methylthio)-2,3-dioxopentyl phosphate + H(2)O.	tmpzr1t_l9r_go_relaxed.owl	S-methyl-5-thio-D-ribulose-1-phosphate hydro-lyase activity|1-PMT-ribulose dehydratase activity|methylthioribulose-1-phosphate dehydratase activity|S-methyl-5-thio-D-ribulose-1-phosphate hydro-lyase [5-(methylthio)-2,3-dioxopentyl-phosphate-forming]|5-methylthioribulose-1-phosphate 4-dehydratase activity|S-methyl-5-thio-D-ribulose-1-phosphate hydro-lyase[5-(methylthio)-2,3-dioxopentyl-phosphate-forming]				RHEA:15549|EC:4.2.1.109|KEGG_REACTION:R07392|MetaCyc:R145-RXN|Reactome:R-HSA-1237140							GO:0043809		molecular_function											owl:Class	
GO:0008821	biolink:NamedThing	crossover junction endodeoxyribonuclease activity	Catalysis of the endonucleolytic cleavage at a junction such as a reciprocal single-stranded crossover between two homologous DNA duplexes (Holliday junction).	tmpzr1t_l9r_go_relaxed.owl	RusA holliday junction resolvase|Holliday junction nuclease activity|Holliday junction-cleaving endonuclease activity|Holliday junction endonuclease CCE1 activity|RusA endonuclease activity|endodeoxyribonuclease RUS activity|RusA Holliday junction resolvase activity|cruciform-cutting endonuclease activity|Holliday junction resolvase activity|Endo X3 activity|endo X3|resolving enzyme CCE1 activity|SpCCe1 holliday junction resolvase|endonuclease RuvC activity|Hje endonuclease activity|RuvC endonuclease activity|endonuclease X3 activity|endonuclease VII activity|crossover junction endoribonuclease activity|Holliday junction-resolving endoribonuclease activity|SpCCe1 Holliday junction resolvase activity				MetaCyc:3.1.22.4-RXN|EC:3.1.22.4							GO:0008844		molecular_function											owl:Class	
GO:0006901	biolink:NamedThing	vesicle coating	A protein coat is added to the vesicle to form the proper shape of the vesicle and to target the vesicle for transport to its destination.	tmpzr1t_l9r_go_relaxed.owl	vesicle coat assembly													biological_process											owl:Class	
GO:0099561	biolink:NamedThing	synaptic membrane adhesion to extracellular matrix	The binding of a synaptic membrane to the extracellular matrix via adhesion molecules.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1990130	biolink:NamedThing	GATOR1 complex	A GTPase-activating protein (GAP) complex that regulates TORC1 signaling by interacting with the Rag GTPase. In human, the GATOR1 complex consists of DEPDC5, NPRL2, and NPRL3. In S. cerevisiae, this complex is referred to as SEACIT and contains the Iml1p, Npr2p, and Npr3p proteins.	tmpzr1t_l9r_go_relaxed.owl	IML1 complex|SEACIT complex	https://github.com/geneontology/go-ontology/issues/21778				The Rag GTPase complex corresponds to Gtr1-Gtr2 GTPase complex ;  GO:1990131.		rb	2013-06-25T17:34:40Z					cellular_component											owl:Class	
GO:0061802	biolink:NamedThing	anterior cell cortex	The region that lies just beneath the plasma membrane in the part of a cell that is closest to the anterior as defined by the developing, or existing, anterior/posterior axis.	tmpzr1t_l9r_go_relaxed.owl								dph	2016-11-06T22:54:21Z					cellular_component											owl:Class	
GO:0004421	biolink:NamedThing	hydroxymethylglutaryl-CoA synthase activity	Catalysis of the reaction: acetoacetyl-CoA + acetyl-CoA + H(2)O = (S)-3-hydroxy-3-methylglutaryl-CoA + CoA + H(+).	tmpzr1t_l9r_go_relaxed.owl	3-hydroxy-3-methylglutaryl-coenzyme A synthase activity|beta-hydroxy-beta-methylglutaryl-CoA synthase activity|(s)-3-hydroxy-3-methylglutaryl-CoA acetoacetyl-CoA-lyase (CoA- acetylating) activity|acetoacetyl coenzyme A transacetase activity|3-hydroxy-3-methylglutaryl CoA synthetase activity|(S)-3-hydroxy-3-methylglutaryl-CoA acetoacetyl-CoA-lyase (CoA-acetylating)|acetyl-CoA:acetoacetyl-CoA C-acetyltransferase (thioester-hydrolysing, carboxymethyl-forming)|3-hydroxy-3-methylglutaryl-CoA synthase activity|3-hydroxy-3-methylglutaryl coenzyme A synthase activity|hydroxymethylglutaryl coenzyme A synthase activity|3-hydroxy-3-methylglutaryl coenzyme A synthetase activity|hydroxymethylglutaryl coenzyme alpha-condensing enzyme activity|hydroxymethylglutaryl coenzyme A-condensing enzyme|HMG-CoA synthase activity				Reactome:R-HSA-191323|MetaCyc:HYDROXYMETHYLGLUTARYL-COA-SYNTHASE-RXN|Reactome:R-HSA-73918|RHEA:10188|EC:2.3.3.10|KEGG_REACTION:R01978	Note that this function was formerly EC:4.1.3.5.								molecular_function											owl:Class	
GO:1990092	biolink:NamedThing	calcium-dependent self proteolysis	The calcium-dependent hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their own peptide bonds.	tmpzr1t_l9r_go_relaxed.owl								sl	2013-05-06T17:33:34Z					biological_process											owl:Class	
GO:0043803	biolink:NamedThing	hydroxyneurosporene-O-methyltransferase activity	Catalysis of the reaction: demethylspheroidene + S-adenosyl-L-methionine = H(+) + S-adenosyl-L-homocysteine + spheroidene.	tmpzr1t_l9r_go_relaxed.owl	1-hydroxycarotenoid methylase|1-hydroxycarotenoid O-methylase|demethylspheroidene O-methyltransferase|1-HO-carotenoid methylase				RHEA:30903|EC:2.1.1.210									molecular_function											owl:Class	
GO:1900783	biolink:NamedThing	fumiquinazoline F catabolic process	The chemical reactions and pathways resulting in the breakdown of fumiquinazoline F.	tmpzr1t_l9r_go_relaxed.owl	fumiquinazoline F catabolism|fumiquinazoline F degradation|fumiquinazoline F breakdown							di	2012-06-04T09:31:27Z					biological_process											owl:Class	
GO:0090633	biolink:NamedThing	keto-deoxynonulosonic acid (KDN) cytidylyltransferase activity	Catalysis of the reaction: CTP + KDN = diphosphate + CMP-KDN.	tmpzr1t_l9r_go_relaxed.owl	cytidine 5'-monophospho-2-Keto-3-deoxy-D-glycero-D-galacto-nononic acid synthetase activity|CMP-KDN synthetase activity							tb	2015-03-19T15:05:54Z					molecular_function											owl:Class	
GO:0046911	biolink:NamedThing	metal chelating activity	The formation of bonds from two or more atoms within the same ligand to a metal atom in complexes in which the metal is part of a ring.	tmpzr1t_l9r_go_relaxed.owl	metal chelation|heavy metal chelation													molecular_function											owl:Class	
GO:0019509	biolink:NamedThing	L-methionine salvage from methylthioadenosine	The generation of L-methionine (2-amino-4-(methylthio)butanoic acid) from methylthioadenosine.	tmpzr1t_l9r_go_relaxed.owl	methionine recycling|methionine salvage from methylthioadenosine|methionine regeneration|methionine salvage pathway				MetaCyc:PWY-4361									biological_process											owl:Class	
GO:0031083	biolink:NamedThing	BLOC-1 complex	A protein complex required for the biogenesis of specialized organelles of the endosomal-lysosomal system, such as melanosomes and platelet dense granules. Many of the protein subunits are conserved between mouse and human; the mouse complex contains the Pallidin, Muted, Cappuccino, Dysbindin, Snapin, BLOS1, BLOS2, AND BLOS3 proteins.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0044541	biolink:NamedThing	zymogen activation in other organism	The chemical reactions and pathways performed by an organism resulting in the proteolytic processing of an inactive enzyme to an active form in another organism.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-03-22T11:39:41Z					biological_process											owl:Class	
GO:0000931	biolink:NamedThing	gamma-tubulin large complex	A complex of gamma tubulin and associated proteins thought to be formed by multimerization of gamma-tubulin small complexes. An example of this structure is found in Schizosaccharomyces pombe.	tmpzr1t_l9r_go_relaxed.owl	gamma-tubulin large complex, spindle pole body|gamma-tubulin large complex, mitotic spindle pole body|gamma-tubulin large complex, iMTOC|gamma-tubulin ring complex, centrosomal|gamma-tubulin large complex, interphase microtubule organizing center|gamma-tubulin ring complex|gamma-tubulin large complex, equatorial microtubule organizing center|gamma-tubulin large complex, equatorial microtubule organizing centre|gamma-tubulin large complex, interphase microtubule organizing centre|gamma-tubulin large complex, centrosomal|gamma-tubulin large complex, eMTOC	https://github.com/geneontology/go-ontology/issues/20967										GO:0000924|GO:0055033|GO:0061494|GO:0000929|GO:0055032|GO:0000925|GO:0008274|GO:0000926|GO:0055031		cellular_component											owl:Class	
GO:0071755	biolink:NamedThing	IgM B cell receptor complex	An IgM immunoglobulin complex that is present in the plasma membrane of B cells and is composed of two identical immunoglobulin heavy chains of the IgM isotype and two identical immunoglobulin light chains and a signaling subunit, a heterodimer of the Ig-alpha and Ig-beta proteins.	tmpzr1t_l9r_go_relaxed.owl	membrane-bound IgM|surface IgM					Note that an IgM immunoglobulin complex has the function of antigen binding if a suitable antigen is available.		mah	2010-03-24T01:44:53Z					cellular_component											owl:Class	
GO:0042595	biolink:NamedThing	behavioral response to starvation	Any process that results in a change in the behavior of an organism as a result of deprivation of nourishment.	tmpzr1t_l9r_go_relaxed.owl	behavioural response to starvation													biological_process											owl:Class	
GO:0042464	biolink:NamedThing	dosage compensation by hypoactivation of X chromosome	Compensating for the two-fold variation in X:autosome chromosome ratios between sexes by an inactivation of a proportion of genes on both of the X chromosomes of the XX sex, leading to a decrease, of half, of the levels of gene expression from these chromosomes. An example of this process is found in Caenorhabditis elegans.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0097665	biolink:NamedThing	SCF-Mdm30 ubiquitin ligase complex	An SCF ubiquitin ligase complex in which the F-box protein is Mdm30 in S. cerevisiae.	tmpzr1t_l9r_go_relaxed.owl								pr	2014-10-06T10:27:30Z					cellular_component											owl:Class	
GO:0033796	biolink:NamedThing	sulfur reductase activity	Catalysis of the reduction of elemental sulfur or polysulfide to hydrogen sulfide.	tmpzr1t_l9r_go_relaxed.owl	(donor):sulfur oxidoreductase activity|sulphur reductase activity				EC:1.12.98.4|RHEA:35591|MetaCyc:RXN-8269|MetaCyc:1.97.1.3-RXN									molecular_function											owl:Class	
GO:0060463	biolink:NamedThing	lung lobe morphogenesis	The process in which the anatomical structures of a lung lobe are generated and organized. A lung lobe is a projection that extends from the lung.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0044687	biolink:NamedThing	geranylfarnesyl diphosphate synthase activity	Catalysis of the reaction: geranylgeranyl diphosphate + isopentenyl diphosphate = (2E,6E,10E,14E)-geranylfarnesyl diphosphate + diphosphate.	tmpzr1t_l9r_go_relaxed.owl					RHEA:25694|MetaCyc:RXN-8813|EC:2.5.1.81			jl	2012-08-15T14:20:25Z					molecular_function											owl:Class	
GO:0007074	biolink:NamedThing	positive regulation of transcription involved in exit from mitosis, from RNA polymerase II promoter	Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as the cell leaves M phase. M phase is the part of the mitotic cell cycle during which mitosis and cytokinesis take place.	tmpzr1t_l9r_go_relaxed.owl	activation of transcription on exit from mitosis, from Pol II promoter|activation of transcription on exit from mitosis, from RNA polymerase II promoter													biological_process											owl:Class	
GO:0002476	biolink:NamedThing	antigen processing and presentation of endogenous peptide antigen via MHC class Ib	The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class Ib protein complex. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E gene family.	tmpzr1t_l9r_go_relaxed.owl	endogenous peptide antigen processing and presentation via MHC class Ib													biological_process											owl:Class	
GO:0004592	biolink:NamedThing	pantoate-beta-alanine ligase activity	Catalysis of the reaction: ATP + (R)-pantoate + beta-alanine = AMP + diphosphate + (R)-pantothenate.	tmpzr1t_l9r_go_relaxed.owl	pantoate-activating enzyme activity|(R)-pantoate:beta-alanine ligase (AMP-forming)|D-pantoate:beta-alanine ligase (AMP-forming)|pantoic-activating enzyme activity|pantothenate synthetase activity				MetaCyc:PANTOATE-BETA-ALANINE-LIG-RXN|RHEA:10912|EC:6.3.2.1									molecular_function											owl:Class	
GO:0047616	biolink:NamedThing	acyl-CoA dehydrogenase (NADP+) activity	Catalysis of the reaction: acyl-CoA + NADP+ = 2,3-dehydroacyl-CoA + NADPH + H+.	tmpzr1t_l9r_go_relaxed.owl	crotonyl coenzyme A reductase activity|enoyl coenzyme A reductase activity|dehydrogenase, acyl coenzyme A (nicotinamide adenine dinucleotide phosphate)|2-enoyl-CoA reductase activity|acyl-CoA:NADP+ 2-oxidoreductase activity				EC:1.3.1.8|RHEA:22460|MetaCyc:ACYL-COA-DEHYDROGENASE-NADP+-RXN									molecular_function											owl:Class	
GO:0047908	biolink:NamedThing	fusarinine-C ornithinesterase activity	Catalysis of the reaction: N5-acyl-L-ornithine ester + H2O = N5-acyl-L-ornithine + an alcohol.	tmpzr1t_l9r_go_relaxed.owl	ornithine esterase activity|5-N-acyl-L-ornithine-ester hydrolase activity|N5-acyl-L-ornithine-ester hydrolase activity				EC:3.1.1.48|MetaCyc:FUSARININE-C-ORNITHINESTERASE-RXN|RHEA:20165									molecular_function											owl:Class	
GO:0052627	biolink:NamedThing	vanillate amino acid synthetase activity	Catalysis of the reaction: vanillate + ATP + amino acid = vanillate amino acid conjugate + AMP + diphosphate.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0070738	biolink:NamedThing	tubulin-glycine ligase activity	Catalysis of the posttranslational transfer of one or more glycine residues to a specific glutamate residue on a target tubulin molecule; acts on alpha or beta tubulin.	tmpzr1t_l9r_go_relaxed.owl	tubulin glycylase activity							mah	2009-06-19T02:02:01Z					molecular_function											owl:Class	
GO:0045771	biolink:NamedThing	negative regulation of autophagosome size	Any process that reduces autophagosome size.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of autophagic vacuole size|inhibition of autophagic vacuole size|down-regulation of autophagic vacuole size|downregulation of autophagic vacuole size|down regulation of autophagic vacuole size													biological_process											owl:Class	
GO:0019410	biolink:NamedThing	aerobic respiration, using carbon monoxide as electron donor	The metabolic process in which carbon monoxide (CO) is oxidized to carbon dioxide (CO2) to generate energy. Conservation of energy in this process likely uses sodium ion gradients for ATP synthesis and is coupled to quantitative sulfide methylation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0099018	biolink:NamedThing	restriction-modification system evasion by virus	Any process, either active or passive, by which a virus evades the DNA restriction modification system of its host. Some viruses encode their own methyltransferase in order to protect their genome from host restriction enzymes. Others directly inhibit restruction enzymes while some use unusual bases in their genome to avoid restriction.	tmpzr1t_l9r_go_relaxed.owl					VZ:3966									biological_process											owl:Class	
GO:0034995	biolink:NamedThing	SC5b-7 complex	A protein complex that consist of complement components C5b6 and C7 stably inserted in a cell membrane. Formation of the SC5b-7 complex is the first phase of membrane attack complex assembly.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0102452	biolink:NamedThing	bisdemethoxycurcumin synthase activity	Catalysis of the reaction: 2 4-coumaryl-CoA + malonyl-CoA + H2O + H+ <=> 3 coenzyme A + bisdemethoxycurcumin + 2 carbon dioxide.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-13958|RHEA:34803|EC:2.3.1.211									molecular_function											owl:Class	
GO:0140701	biolink:NamedThing	3',3'-cyclic GMP-AMP synthase activity	Catalysis of the reaction: ATP + GTP = 2 diphosphate + cyclic G-P(3'-5')A-P(3'-5') (cyclic 3',3' GAMP).	tmpzr1t_l9r_go_relaxed.owl	3',3'-cyclic GAMP synthase activity|3',3' cyclic-GMP-AMP synthase activity|3',3' cyclic-GAMP synthase activity	https://github.com/geneontology/go-ontology/issues/21980			RHEA:35647			pg	2021-08-27T05:13:09Z					molecular_function											owl:Class	
GO:0047806	biolink:NamedThing	cytochrome-c3 hydrogenase activity	Catalysis of the reaction: 2 H2 + ferricytochrome c3 = 4 H+ + ferrocytochrome c3.	tmpzr1t_l9r_go_relaxed.owl	hydrogen:ferricytochrome-c3 oxidoreductase activity|cytochrome c3 reductase activity|H2:ferricytochrome c3 oxidoreductase activity|H(2):ferricytochrome c3 oxidoreductase activity|cytochrome hydrogenase activity				MetaCyc:CYTOCHROME-C3-HYDROGENASE-RXN|EC:1.12.2.1|UM-BBD_enzymeID:e0481|RHEA:20625									molecular_function											owl:Class	
GO:0043483	biolink:NamedThing	anthocyanin biosynthetic process involved in anthocyanin accumulation in response to UV light	The chemical reactions and pathways resulting in the formation of the pigment anthocyanin, contributing to anthocyanin accumulation in a tissue in response to a UV light stimulus.	tmpzr1t_l9r_go_relaxed.owl	anthocyanin biosynthetic process during anthocyanin accumulation in tissues in response to UV light stimulus|anthocyanin biosynthesis during anthocyanin accumulation in tissues in response to UV light stimulus|anthocyanin biosynthetic process during anthocyanin accumulation in response to UV light													biological_process											owl:Class	
GO:0004380	biolink:NamedThing	glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase activity	Catalysis of the reaction: UDP-N-acetyl-D-galactosamine + glycoprotein-alpha-L-fucosyl-(1,2)-D-galactose = UDP + glycoprotein-N-acetyl-alpha-D-galactosaminyl-(1,3)-(alpha-L-fucosyl-(1,2))-D-galactose.	tmpzr1t_l9r_go_relaxed.owl	A transferase activity|blood-group substance alpha-acetyltransferase activity|UDP-N-acetyl-D-galactosamine:glycoprotein-alpha-L-fucosyl-(1,2)-D-galactose 3-N-acetyl-D-galactosaminyltransferase activity|fucosylglycoprotein alpha-N-acetylgalactosaminyltransferase activity|histo-blood group A acetylgalactosaminyltransferase activity|blood-group substance A-dependent acetylgalactosaminyltransferase activity|UDP-GalNAc:Fucalpha1->2Galalpha1->3-N-acetylgalactosaminyltransferase activity|fucosylgalactose acetylgalactosaminyltransferase activity|fucosylgalactose alpha-N-acetylgalactosaminyltransferase activity|histo-blood group A glycosyltransferase (Fucalpha1->2Galalpha1->3-N-acetylgalactosaminyltransferase)|A-transferase activity|histo-blood group A transferase activity|alpha-3-N-acetylgalactosaminyltransferase activity|UDP-N-acetyl-D-galactosamine:alpha-L-fucosyl-1,2-D-galactose 3-N-acetyl-D-galactosaminyltransferase activity				RHEA:19021|Reactome:R-HSA-9034042|EC:2.4.1.40|MetaCyc:2.4.1.40-RXN|Reactome:R-HSA-9033959									molecular_function											owl:Class	
GO:0034947	biolink:NamedThing	terephthalate decarboxylase activity	Catalysis of the reaction: terephthalate + H2O = benzoate + HCO3-.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0321									molecular_function											owl:Class	
GO:0007375	biolink:NamedThing	anterior midgut invagination	Internalization of the anterior midgut into the interior of the embryo.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0004077	biolink:NamedThing	biotin-[acetyl-CoA-carboxylase] ligase activity	Catalysis of the reaction: ATP + biotin + apo-(acetyl-CoA:carbon-dioxide ligase (ADP forming)) = AMP + diphosphate + (acetyl-CoA:carbon-dioxide ligase (ADP forming)).	tmpzr1t_l9r_go_relaxed.owl	HCS|biotin-acetyl-CoA-carboxylase ligase activity|acetyl CoA holocarboxylase synthetase activity|acetyl coenzyme A holocarboxylase synthetase activity|biotin holoenzyme synthetase activity|biotin:apo-acetyl-CoA:carbon-dioxide ligase (ADP-forming) ligase (AMP-forming)|biotin-acetyl coenzyme A carboxylase synthetase activity|biotin--protein ligase activity|biotin:apocarboxylase ligase activity|biotin--[acetyl-CoA carboxylase] synthetase activity|acetyl-CoA carboxylase biotin holoenzyme synthetase activity|biotin-acetyl-CoA carboxylase synthetase				MetaCyc:BIOTINLIG-RXN|RHEA:11756|EC:6.3.4.15									molecular_function											owl:Class	
GO:0071053	biolink:NamedThing	alpha9-beta1 integrin-ADAM2 complex	A protein complex that consists of an alpha9-beta1 integrin complex bound to the transmembrane metallopeptidase ADAM2.	tmpzr1t_l9r_go_relaxed.owl	ITGA9-ITGB1-ADAM2 complex							mah	2009-11-03T03:58:22Z					cellular_component											owl:Class	
GO:1902768	biolink:NamedThing	isoprenoid biosynthetic process via 1-deoxy-D-xylulose 5-phosphate	The chemical reactions and pathways resulting in the formation of isoprenoid via 1-deoxy-D-xylulose 5-phosphate.	tmpzr1t_l9r_go_relaxed.owl	isoprenoid synthesis via 1-deoxy-D-xylulose 5-phosphate|isoprenoid biosynthesis via 1-deoxy-D-xylulose 5-phosphate|isoprenoid anabolism via 1-deoxy-D-xylulose 5-phosphate|isoprenoid formation via 1-deoxy-D-xylulose 5-phosphate							tt	2014-03-11T00:09:55Z					biological_process											owl:Class	
GO:0008510	biolink:NamedThing	sodium:bicarbonate symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Na+(out) + HCO3-(out) = Na+(in) + HCO3-(in).	tmpzr1t_l9r_go_relaxed.owl	sodium/bicarbonate cotransporter activity|sodium:bicarbonate cotransporter activity				Reactome:R-HSA-425483|Reactome:R-HSA-5656219|Reactome:R-HSA-8878664									molecular_function											owl:Class	
GO:0051500	biolink:NamedThing	D-tyrosyl-tRNA(Tyr) deacylase activity	Catalysis of the reaction: D-tyrosyl-tRNA(Tyr) = D-tyrosine + tRNA(Tyr). Hydrolysis of the removal of D-tyrosine from tyrosine residues in charged tRNA.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0061582	biolink:NamedThing	intestinal epithelial cell migration	The orderly movement of an intestinal epithelial cell from one site to another, often during the development of a multicellular organism.	tmpzr1t_l9r_go_relaxed.owl								dph	2013-12-23T07:30:55Z					biological_process											owl:Class	
GO:0060447	biolink:NamedThing	bud outgrowth involved in lung branching	The process in which a region of the lung epithelium initiates an outgrowth.	tmpzr1t_l9r_go_relaxed.owl	bud formation involved in lung branching													biological_process											owl:Class	
GO:0008459	biolink:NamedThing	chondroitin 6-sulfotransferase activity	Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + chondroitin = adenosine 3',5'-bisphosphate + chondroitin 6'-sulfate.	tmpzr1t_l9r_go_relaxed.owl	3'-phosphoadenylyl-sulfate:chondroitin 6'-sulfotransferase activity|terminal 6-sulfotransferase activity|chondroitin 6-sulphotransferase activity|3'-phosphoadenosine 5'-phosphosulfate (PAPS):chondroitin sulfate sulfotransferase activity|chondroitin 6-O-sulfotransferase activity				MetaCyc:CHONDROITIN-6-SULFOTRANSFERASE-RXN|EC:2.8.2.17|Reactome:R-HSA-3595175|Reactome:R-HSA-2018682|RHEA:11108									molecular_function											owl:Class	
GO:0034245	biolink:NamedThing	mitochondrial DNA-directed RNA polymerase complex	A DNA-directed RNA polymerase complex located in the mitochondrion. Mitochondrial RNA polymerase is composed of two subunits, a catalytic core, which resembles the enzymes from bacteriophage T7 and T3, and a specificity factor required for promoter recognition, which is similar to members of the eubacterial sigma factor family. In S. cerevisiae, these are encoded by the nuclear genes RPO41 and MTF1 and the specificity factor, required for promoter recognition and initiation, is not present in the elongating form.	tmpzr1t_l9r_go_relaxed.owl	mitochondrial RNA polymerase complex|mitochondrial RNA polymerase holoenzyme complex													cellular_component											owl:Class	
GO:2000701	biolink:NamedThing	glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation	The series of molecular signals generated as a consequence of a glial cell-derived neurotrophic factor receptor binding to one of its physiological ligands that contributes to the formation of the ureteric bud from the Wolffian duct.	tmpzr1t_l9r_go_relaxed.owl	GDNF receptor signaling pathway of ureteric bud formation|glial cell derived neurotrophic factor receptor signaling pathway of ureteric bud formation|glial cell-derived neurotrophic factor receptor signalling pathway of ureteric bud formation|glial cell line-derived neurotrophic factor receptor signalling pathway of ureteric bud formation|glial cell-derived neurotrophic factor receptor signaling pathway of ureteric bud formation							yaf	2011-05-25T09:34:07Z					biological_process											owl:Class	
GO:0120318	biolink:NamedThing	olfactory sociosexual communication	The use of external chemical cues called pheromones to send social and sexual information between members of the same species, leading to specific behavioral responses. Pheromones may be detected by two olfactory sensory circuits, the main olfactory pathway and the vomeronasal system.	tmpzr1t_l9r_go_relaxed.owl						Behavior such as predation which involves members of different species is not social. Communication between members of different species is also not social behavior.		krc	2021-05-21T19:35:58Z					biological_process											owl:Class	
GO:0043850	biolink:NamedThing	RecFOR complex	A heterotrimeric complex composed of the subunits RecF, RecO and RecR. Mediates the loading of RecA protein specifically onto SSB-coated gapped DNA during DNA repair.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0046383	biolink:NamedThing	dTDP-rhamnose metabolic process	The chemical reactions and pathways involving dTDP-rhamnose, a substance composed of rhamnose in glycosidic linkage with deoxyribosylthymine diphosphate.	tmpzr1t_l9r_go_relaxed.owl	dTDP-rhamnose metabolism													biological_process											owl:Class	
GO:0006705	biolink:NamedThing	mineralocorticoid biosynthetic process	The chemical reactions and pathways resulting in the formation of mineralocorticoids, hormonal C21 corticosteroids synthesized from cholesterol.	tmpzr1t_l9r_go_relaxed.owl	mineralocorticoid formation|mineralocorticoid synthesis|mineralocorticoid biosynthesis|mineralocorticoid anabolism													biological_process											owl:Class	
GO:0047928	biolink:NamedThing	gibberellin beta-D-glucosyltransferase activity	Catalysis of the reaction: UDP-glucose + gibberellin = UDP + gibberellin 2-O-beta-D-glucoside.	tmpzr1t_l9r_go_relaxed.owl	gibberellin b-glucosyltransferase activity|uridine diphosphoglucose-gibberellate 7-glucosyltransferase activity|UDP-glucose:gibberellin 2-O-beta-D-glucosyltransferase activity|uridine diphosphoglucose-gibberellate 3-O-glucosyltransferase activity|UDPglucose:gibberellin 2-O-beta-D-glucosyltransferase activity				RHEA:20025|MetaCyc:GIBBERELLIN-BETA-GLUCOSYLTRANSFERASE-RXN|EC:2.4.1.176									molecular_function											owl:Class	
GO:0102716	biolink:NamedThing	gibberellin A28,oxoglutarate:oxygen oxidoreductase activity	Catalysis of the reaction: gibberellin A28 + 2-oxoglutarate + O2 <=> (2betaOH)-gibberellin28 + succinate + carbon dioxide.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-6547									molecular_function											owl:Class	
GO:0018256	biolink:NamedThing	protein formylation	The addition of a formyl group to a protein amino acid.	tmpzr1t_l9r_go_relaxed.owl	protein amino acid formylation													biological_process											owl:Class	
GO:1902971	biolink:NamedThing	mitotic DNA replication DNA duplex unwinding	Any DNA duplex unwinding involved in mitotic cell cycle DNA replication.	tmpzr1t_l9r_go_relaxed.owl	DNA duplex unwinding involved in mitotic DNA replication|DNA duplex unwinding involved in mitotic cell cycle DNA replication							jl	2014-05-06T15:20:47Z					biological_process											owl:Class	
GO:0008697	biolink:NamedThing	4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase activity	Catalysis of the reaction: 5-dehydro-4-deoxy-D-glucuronate = 3-deoxy-D-glycero-2,5-hexodiulosonate.	tmpzr1t_l9r_go_relaxed.owl	4-deoxy-L-threo-5-hexosulose-uronate aldose-ketose-isomerase activity|4-deoxy-L-threo-5-hexulose uronate isomerase activity|5-keto-4-deoxyuronate isomerase activity				EC:5.3.1.17|KEGG_REACTION:R04383|RHEA:23896|MetaCyc:5.3.1.17-RXN									molecular_function											owl:Class	
GO:0072557	biolink:NamedThing	IPAF inflammasome complex	An inflammasome complex that consists of three components, IPAF, NAIP and caspase-1, and includes among its functions the sensing of flagellin derived from Legionella pneumophila, Salmonella typhimurium, Pseudomonas aeruginosa and Shigella flexneri.	tmpzr1t_l9r_go_relaxed.owl								mah	2011-01-27T12:01:44Z					cellular_component											owl:Class	
GO:0038062	biolink:NamedThing	protein tyrosine kinase collagen receptor activity	Combining with collagen and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: ATP + a protein-L-tyrosine = ADP + a protein-L-tyrosine phosphate.	tmpzr1t_l9r_go_relaxed.owl	collagen RTK activity|discoidin domain receptor							bf	2012-01-18T01:38:40Z					molecular_function											owl:Class	
GO:0008404	biolink:NamedThing	arachidonic acid 14,15-epoxygenase activity	Catalysis of an NADPH- and oxygen-dependent reaction that converts arachidonic acid to cis-14,15-epoxyeicosatrienoic acid.	tmpzr1t_l9r_go_relaxed.owl	cytochrome P450 CYP2C39|cytochrome P450 CYP2C29				RHEA:51472									molecular_function											owl:Class	
GO:0072169	biolink:NamedThing	specification of posterior mesonephric tubule identity	The process in which the tubules of the posterior mesonephros acquire their identity.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-02-26T01:54:06Z					biological_process											owl:Class	
GO:0004816	biolink:NamedThing	asparagine-tRNA ligase activity	Catalysis of the reaction: L-asparagine + ATP + tRNA(Asn) = AMP + Asn-tRNA(Asn) + diphosphate + 2 H(+).	tmpzr1t_l9r_go_relaxed.owl	L-asparagine:tRNAAsn ligase (AMP-forming)|asparaginyl transfer RNA synthetase activity|asparaginyl-tRNA synthetase activity|asparaginyl-transfer ribonucleate synthetase activity|asparagyl-transfer RNA synthetase activity|asparagine translase activity|asparaginyl transfer ribonucleic acid synthetase activity				Reactome:R-HSA-379996|RHEA:11180|MetaCyc:ASPARAGINE--TRNA-LIGASE-RXN|Reactome:R-HSA-380227|KEGG_REACTION:R03648|EC:6.1.1.22									molecular_function											owl:Class	
GO:0034328	biolink:NamedThing	decanoyltransferase activity	Catalysis of the transfer of a decanoyl (CH3-[CH2]8-CO-) group to an acceptor molecule.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0103037	biolink:NamedThing	L-glyceraldehyde 3-phosphate reductase activity	Catalysis of the reaction: sn-glycerol 3-phosphate + NADP = H+ + L-glyceraldehyde 3-phosphate + NADPH.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN0-5410									molecular_function											owl:Class	
GO:0031044	biolink:NamedThing	O-glycan processing, core 8	The stepwise addition of carbohydrate or carbohydrate derivative residues to the initially added O-linked residue (usually GalNAc) to form the core 8 O-glycan structure, Gal-alpha-(1->3)-GalNAc.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0070310	biolink:NamedThing	ATR-ATRIP complex	A protein complex that contains the protein kinase ATR and ATR-interacting protein (ATRIP) and binds single-stranded DNA; ssDNA binding affinity is increased in the presence of replication protein A.	tmpzr1t_l9r_go_relaxed.owl	Mec1-Lcd1 complex|Rad3-Rad26 complex													cellular_component											owl:Class	
GO:0050014	biolink:NamedThing	ketotetrose-phosphate aldolase activity	Catalysis of the reaction: L-erythrulose 1-phosphate = formaldehyde + glycerone phosphate.	tmpzr1t_l9r_go_relaxed.owl	erythrulose-1-phosphate formaldehyde-lyase (glycerone-phosphate-forming)|erythrose-1-phosphate synthase activity|erythrulose-1-phosphate formaldehyde-lyase activity|erythrulose-1-phosphate synthetase activity|phosphoketotetrose aldolase activity				RHEA:20932|MetaCyc:KETOTETROSE-PHOSPHATE-ALDOLASE-RXN|EC:4.1.2.2|KEGG_REACTION:R01014									molecular_function											owl:Class	
GO:0032051	biolink:NamedThing	clathrin light chain binding	Binding to a clathrin light chain.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0102777	biolink:NamedThing	caffeoyl-CoA:pelargonidin-3,5-diglucoside 5-O-glucoside-6-O-hydroxycinnamoyltransferase activity	Catalysis of the reaction: anthocyanidin 3,5-di-O-beta-D-glucoside + caffeoyl-CoA <=> pelargonidin-3,5-diglucoside-5-O-caffeoylglucoside + coenzyme A(4-).	tmpzr1t_l9r_go_relaxed.owl					EC:2.3.1.153|MetaCyc:RXN-7842									molecular_function											owl:Class	
GO:1903577	biolink:NamedThing	cellular response to L-arginine	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-arginine stimulus.	tmpzr1t_l9r_go_relaxed.owl								mr	2014-10-29T22:18:54Z					biological_process											owl:Class	
GO:0047852	biolink:NamedThing	diferric-transferrin reductase activity	Catalysis of the reaction: transferrin[Fe2+]2 + NAD+ = transferrin[Fe3+]2 + NADH.	tmpzr1t_l9r_go_relaxed.owl	transferrin reductase activity|diferric transferrin reductase activity|NADH diferric transferrin reductase activity|transferrin[Fe(II)]2:NAD+ oxidoreductase activity				RHEA:13841|MetaCyc:DIFFERIC-TRANSFERRIN-REDUCTASE-RXN|EC:1.16.1.2									molecular_function											owl:Class	
GO:0140423	biolink:NamedThing	effector-mediated suppression of host pattern-triggered immunity signaling	A process mediated by a molecule secreted by a symbiont that results in the suppression of a pattern-triggered immunity PTI signaling pathway. PTI signaling pathways are found in plants.	tmpzr1t_l9r_go_relaxed.owl	effector-mediated suppression of pattern-triggered immunity signaling|effector-mediated suppression of host PRR signalling|effector-mediated suppression of host PRR signaling|effector-mediated suppression of host pattern recognition receptor signaling|effector-mediated suppression of PTI signalling	https://github.com/geneontology/go-ontology/issues/18683						pg	2020-02-03T09:50:33Z					biological_process											owl:Class	
GO:0052914	biolink:NamedThing	16S rRNA (guanine(1207)-N(2))-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + guanosine(1207) in 16S rRNA = N(2)-methylguanosine(1207) in 16S rRNA + S-adenosyl-L-homocysteine.	tmpzr1t_l9r_go_relaxed.owl	M(2)G1207 methyltransferase activity				EC:2.1.1.172|KEGG_REACTION:R07234|RHEA:42736|MetaCyc:RXN-11576									molecular_function											owl:Class	
GO:0102349	biolink:NamedThing	trans-lignocero-2-enoyl-CoA reductase activity	Catalysis of the reaction: tetracosanoyl-CoA + NADP <=> trans-2-tetracosenoyl-CoA + NADPH + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-13308									molecular_function											owl:Class	
GO:0015382	biolink:NamedThing	sodium:sulfate symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sulfate(out) + Na+(out) = sulfate(in) + Na+(in).	tmpzr1t_l9r_go_relaxed.owl	sodium:sulfate cotransporter activity|sodium:sulphate symporter activity				Reactome:R-HSA-433114|Reactome:R-HSA-433099									molecular_function											owl:Class	
GO:0048555	biolink:NamedThing	generative cell nucleus	The nucleus of the generative cell, a cell contained within the pollen grain that will divide to produce two haploid sperm cells.	tmpzr1t_l9r_go_relaxed.owl	sperm cell nucleus|male germ cell nucleus													cellular_component											owl:Class	
GO:0102985	biolink:NamedThing	delta12-fatty-acid desaturase activity	Catalysis of the reaction: oleoyl-CoA + O2 + a reduced electron acceptor <=> linoleoyl-CoA + 2 H2O + an oxidized electron acceptor. This microsomal enzyme introduces a cis double bond at position 12 of fatty-acyl-CoAs that contain a cis double bond at position 9.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-9601|EC:1.14.19.6|RHEA:25856									molecular_function											owl:Class	
GO:1904350	biolink:NamedThing	regulation of protein catabolic process in the vacuole	Any process that modulates the frequency, rate or extent of protein catabolic process in the vacuole.	tmpzr1t_l9r_go_relaxed.owl	regulation of vacuolar protein degradation|regulation of vacuolar protein catabolism|regulation of vacuolar protein breakdown|regulation of vacuolar protein catabolic process							rl	2015-06-12T09:10:36Z					biological_process											owl:Class	
GO:0047048	biolink:NamedThing	3-hydroxybenzyl-alcohol dehydrogenase activity	Catalysis of the reaction: 3-hydroxybenzyl alcohol + NADP(+) = 3-hydroxybenzaldehyde + H(+) + NADPH.	tmpzr1t_l9r_go_relaxed.owl	3-hydroxybenzyl-alcohol:NADP+ oxidoreductase activity|m-hydroxybenzyl alcohol (NADP) dehydrogenase activity|m-hydroxybenzylalcohol dehydrogenase activity|m-hydroxybenzyl alcohol dehydrogenase activity				KEGG_REACTION:R04136|MetaCyc:1.1.1.97-RXN|EC:1.1.1.97|RHEA:22340									molecular_function											owl:Class	
GO:0060279	biolink:NamedThing	positive regulation of ovulation	Any process that activates or increases the frequency, rate or extent of ovulation, the release of a mature ovum/oocyte from an ovary.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0043754	biolink:NamedThing	dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity	Catalysis of the reaction: 2-methylpropanoyl-CoA + enzyme N6-(dihydrolipoyl)lysine = CoA + enzyme N6-(S-[2-methylpropanoyl]dihydrolipoyl)lysine.	tmpzr1t_l9r_go_relaxed.owl	dihydrolipoyl transacylase activity|enzyme-dihydrolipoyllysine:2-methylpropanoyl-CoA S-(2-methylpropanoyl)transferase activity|2-methylpropanoyl-CoA:enzyme-N6-(dihydrolipoyl)lysine:S-(2-methylpropanoyl)transferase activity|2-methylpropanoyl-CoA:enzyme-6-N-(dihydrolipoyl)lysine:S-(2-methylpropanoyl)transferase activity				MetaCyc:2.3.1.168-RXN|RHEA:18865|EC:2.3.1.168									molecular_function											owl:Class	
GO:0106271	biolink:NamedThing	D-arabinose 1-dehydrogenase (NADP+) activity	Catalysis of the reaction: D-arabinose + NADP+ = D-arabinono-1,4-lactone + NADPH.	tmpzr1t_l9r_go_relaxed.owl					RHEA:21892|EC:1.1.1.117			hjd	2020-06-23T18:47:25Z					molecular_function											owl:Class	
GO:1901062	biolink:NamedThing	guaiacyl lignin catabolic process	The chemical reactions and pathways resulting in the breakdown of guaiacyl lignin.	tmpzr1t_l9r_go_relaxed.owl	G-lignin catabolic process|guaiacyl lignin degradation|guaiacyl lignin catabolism|guaiacyl lignin breakdown							tt	2012-06-29T02:47:03Z					biological_process											owl:Class	
GO:0003234	biolink:NamedThing	bulbus arteriosus formation	The developmental process pertaining to the initial formation of the bulbus arteriosus from unspecified parts. The bulbus arteriosus is an elastic chamber of the heart.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-10-13T11:10:02Z					biological_process											owl:Class	
GO:0047857	biolink:NamedThing	dihydrouracil oxidase activity	Catalysis of the reaction: 5,6-dihydrouracil + O(2) = H(2)O(2) + uracil.	tmpzr1t_l9r_go_relaxed.owl	5,6-dihydrouracil:oxygen oxidoreductase activity				EC:1.3.3.7|MetaCyc:DIHYDROURACIL-OXIDASE-RXN|KEGG_REACTION:R00975|RHEA:12384									molecular_function											owl:Class	
GO:0140251	biolink:NamedThing	regulation protein catabolic process at presynapse	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein at the presynapse.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/synapse/issues/204				Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.		pg	2018-07-15T10:35:39Z					biological_process											owl:Class	
GO:0031859	biolink:NamedThing	platelet activating factor receptor binding	Binding to a platelet activating factor receptor.	tmpzr1t_l9r_go_relaxed.owl	platelet activating factor receptor ligand													molecular_function											owl:Class	
GO:0098006	biolink:NamedThing	viral DNA genome packaging, headful	The encapsulation of the viral genome within the capsid where DNA is packaged into the capsid until the capsid is full.	tmpzr1t_l9r_go_relaxed.owl	phage headful packaging					Generalized transducing phages usually use this mode of DNA packaging.		bm	2012-07-18T16:15:09Z					biological_process											owl:Class	
GO:0070620	biolink:NamedThing	EGFR-Grb2-Sos complex	A protein complex that contains the epidermal growth factor receptor (EGFR), Grb2 and the guanine nucleotide exchange factor Sos (or an ortholog thereof, such as mSos1), and is involved in linking EGFR activation to the p21-Ras pathway.	tmpzr1t_l9r_go_relaxed.owl	Egfr-Grb2-mSos1 complex, EGF stimulated							mah	2009-04-29T04:36:30Z					cellular_component											owl:Class	
GO:0003119	biolink:NamedThing	regulation of vasoconstriction by neuronal epinephrine	Any process that modulates the frequency, rate or extent of reductions in the diameter of blood vessels as a result of epinephrine released by nerve endings.	tmpzr1t_l9r_go_relaxed.owl	regulation of vasoconstriction by neuronal adrenaline													biological_process											owl:Class	
GO:0003115	biolink:NamedThing	regulation of vasoconstriction by epinephrine	Any process that modulates the frequency, rate or extent of reductions in the diameter of blood vessels as a result of secretion of epinephrine into the bloodstream or released by nerve endings.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0006735	biolink:NamedThing	NADH regeneration	A metabolic process that generates a pool of NADH by the reduction of NAD+.	tmpzr1t_l9r_go_relaxed.owl	reduced NAD regeneration|NAD (reduced) regeneration|reduced nicotinamide adenine dinucleotide regeneration													biological_process											owl:Class	
GO:0047357	biolink:NamedThing	UDP-galactose-UDP-N-acetylglucosamine galactose phosphotransferase activity	Catalysis of the reaction: UDP-N-acetyl-alpha-D-glucosamine + UDP-D-galactose = H(+) + UDP-N-acetyl-6-(D-galactose-1-phospho)-D-glucosamine + UMP.	tmpzr1t_l9r_go_relaxed.owl	UDPgalactose-UDP-N-acetylglucosamine galactose phosphotransferase activity|UDP-galactose:UDP-N-acetyl-D-glucosamine galactose phosphotransferase activity|galactose-1-phosphotransferase activity|galactosyl phosphotransferase activity|uridine diphosphogalactose-uridine diphosphoacetylglucosamine galactose-1-phosphotransferase activity|UDPgalactose:UDP-N-acetyl-D-glucosamine galactose phosphotransferase activity				KEGG_REACTION:R00504|RHEA:22440|MetaCyc:2.7.8.18-RXN|EC:2.7.8.18									molecular_function											owl:Class	
GO:0080069	biolink:NamedThing	7-methylthioheptyl-desulfoglucosinolate sulfotransferase activity	Catalysis of the reaction: 7-methylthioheptyl-desulfoglucosinolate + 3'-phosphoadenosine 5'-phosphosulfate = 7-methylthioheptyl-glucosinolate + adenosine 3',5'-bisphosphate.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXNQT-4332			dhl	2009-04-13T04:07:32Z					molecular_function											owl:Class	
GO:0031755	biolink:NamedThing	Edg-2 lysophosphatidic acid receptor binding	Binding to an Edg-2 lysophosphatidic acid receptor.	tmpzr1t_l9r_go_relaxed.owl	LPA1 receptor binding|Edg-2 lysophosphatidic acid receptor ligand													molecular_function											owl:Class	
GO:0098990	biolink:NamedThing	AMPA selective glutamate receptor signaling pathway	A series of molecular signals initiated by glutamate binding to an AMPA-selective glutamate receptor on the surface of the target cell, followed by the movement of ions through a channel in the receptor complex. Ends with regulation of a downstream cellular process, e.g. transcription.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0035199	biolink:NamedThing	salt aversion	The specific avoidance actions or reactions of an organism in response to the perception of salt.	tmpzr1t_l9r_go_relaxed.owl	behavioral response to salt													biological_process											owl:Class	
GO:0005091	biolink:NamedThing	guanyl-nucleotide exchange factor adaptor activity	The binding activity of a molecule that brings together a guanyl-nucleotide exchange factor and one or more other proteins, permitting them to function in a coordinated way.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0043841	biolink:NamedThing	(S)-lactate 2-kinase activity	Catalysis of the reaction: (S)-lactate + GTP = 2-phospho-(S)-lactate + GDP.	tmpzr1t_l9r_go_relaxed.owl	lactate 2-kinase activity				MetaCyc:RXN-8076									molecular_function											owl:Class	
GO:0043888	biolink:NamedThing	(S)-2,3-di-O-geranylgeranylglyceryl phosphate synthase activity	Catalysis of the transfer of a geranylgeranyl group from geranylgeranyl diphosphate to (S)-3-O-geranylgeranylglyceryl phosphate to form (S)-2,3-di-O-geranylgeranylglyceryl phosphate.	tmpzr1t_l9r_go_relaxed.owl	DGGGP synthase activity|DGGGPS|2,3-dGGGPS|UbiA				EC:2.5.1.-	This function is involved in archaeal lipid synthesis.								molecular_function											owl:Class	
GO:0031476	biolink:NamedThing	myosin VI complex	A myosin complex containing one or more class VI myosin heavy chains and associated light chains. Myosin VI has a single IQ motif in the neck and a tail region with a coiled coil domain followed by a unique globular domain; a unique insertion that enables myosin VI to move towards the pointed or minus end of actin filaments.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0034676	biolink:NamedThing	integrin alpha6-beta4 complex	An integrin complex that comprises one alpha6 subunit and one beta4 subunit.	tmpzr1t_l9r_go_relaxed.owl	alpha6-beta4 integrin complex|ITGA6-ITGB4 complex													cellular_component											owl:Class	
GO:0034210	biolink:NamedThing	sterol deacetylation	The removal of an acetyl group from a sterol molecule. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0034208	biolink:NamedThing	steroid deacetylation	The removal of an acetyl group from a steroid molecule. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0035862	biolink:NamedThing	dITP metabolic process	The chemical reactions and pathways involving dITP (deoxyinosine triphosphate (2'-deoxyinosine 5'-triphosphate). dITP is a deoxyinosine phosphate compound having a triphosphate group at the 5'-position.	tmpzr1t_l9r_go_relaxed.owl	2'-Deoxyinosine-5'-triphosphate metabolic process|dITP metabolism|2'-Deoxyinosine 5'-triphosphate metabolic process|deoxyinosine 5'-triphosphate metabolic process|deoxyinosine triphosphate (2'-deoxyinosine 5'-triphosphate) metabolic process							bf	2011-05-25T02:52:58Z					biological_process											owl:Class	
GO:0085030	biolink:NamedThing	symbiotic process benefiting host	A process carried out by symbiont gene products that enables a symbiotic interaction with a host organism, that is beneficial to the host organism.	tmpzr1t_l9r_go_relaxed.owl	mutualism							jl	2010-07-27T01:25:21Z					biological_process											owl:Class	
GO:0009340	biolink:NamedThing	DNA topoisomerase IV complex	A heterodimeric enzyme, which in most bacterial species is composed of two subunits, ParC and ParE. Functions in chromosome segregation and can relax supercoiled DNA.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0000269	biolink:NamedThing	toxin export channel activity	Enables the energy independent passage of toxins, sized less than 1000 Da, across a membrane towards the outside of the cell. The transmembrane portions of porins consist exclusively of beta-strands which form a beta-barrel. They are found in the outer membranes of Gram-negative bacteria, mitochondria, plastids and possibly acid-fast Gram-positive bacteria.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0021752	biolink:NamedThing	inferior salivary nucleus development	The process whose specific outcome is the progression of the inferior salivary nucleus over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1903982	biolink:NamedThing	negative regulation of microvillus length	A process that decreases the length of a microvillus.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of regulation of microvillus length|downregulation of regulation of microvillus length|down regulation of regulation of microvillus length|inhibition of regulation of microvillus length							als	2015-03-03T13:23:52Z					biological_process											owl:Class	
GO:0034066	biolink:NamedThing	Ric1-Rgp1 guanyl-nucleotide exchange factor complex	A protein complex that acts as a nucleotide exchange factor for the GTPase Ypt6p, and is required for fusion of endosome-derived vesicles with the Golgi.	tmpzr1t_l9r_go_relaxed.owl	Ric1p-Rgp1p complex													cellular_component											owl:Class	
GO:0070840	biolink:NamedThing	dynein complex binding	Binding to a dynein complex, a protein complex that contains two or three dynein heavy chains and several light chains, and has microtubule motor activity.	tmpzr1t_l9r_go_relaxed.owl	dynein binding							mah	2009-07-31T01:22:47Z			GO:0045502		molecular_function											owl:Class	
GO:0052927	biolink:NamedThing	CTP:tRNA cytidylyltransferase activity	Catalysis of the reaction: a tRNA precursor + CTP = a tRNA with a 3' cytidine end + diphosphate.	tmpzr1t_l9r_go_relaxed.owl					EC:2.7.7.72|KEGG_REACTION:R09383									molecular_function											owl:Class	
GO:0008352	biolink:NamedThing	katanin complex	A complex possessing an activity that couples ATP hydrolysis to the severing of microtubules; usually a heterodimer comprising a catalytic subunit (often 60kDa) and a regulatory subunit (often 80 kDa).	tmpzr1t_l9r_go_relaxed.owl						Consider also annotating to the molecular function term 'microtubule-severing ATPase activity ; GO:0008568'.								cellular_component											owl:Class	
GO:0034832	biolink:NamedThing	geranial dehydrogenase activity	Catalysis of the reaction: geranial + NAD+ + OH- = geranylate + NADH + H+.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r1164									molecular_function											owl:Class	
GO:0102821	biolink:NamedThing	bixin methyltransferase activity	Catalysis of the reaction: bixin + S-adenosyl-L-methionine  <=> bixin dimethyl ester + S-adenosyl-L-homocysteine.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-8239									molecular_function											owl:Class	
GO:0005056	biolink:NamedThing	tiggrin receptor activity	Combining with the extracellular matrix ligand tiggrin, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0048032	biolink:NamedThing	galacturonate binding	Binding to a galacturonate. Galacturonate is the anion of galacturonic acid, the uronic acid formally derived from galactose by oxidation of the hydroxymethylene group at C-6 to a carboxyl group.	tmpzr1t_l9r_go_relaxed.owl	galacturonic acid binding													molecular_function											owl:Class	
GO:0005827	biolink:NamedThing	polar microtubule	Any of the spindle microtubules that come from each pole and overlap at the spindle midzone. This interdigitating structure consisting of antiparallel microtubules is responsible for pushing the poles of the spindle apart.	tmpzr1t_l9r_go_relaxed.owl	pole-to-pole microtubule													cellular_component											owl:Class	
GO:0008440	biolink:NamedThing	inositol-1,4,5-trisphosphate 3-kinase activity	Catalysis of the reaction: 1D-myo-inositol 1,4,5-trisphosphate + ATP = 1D-myo-inositol 1,3,4,5-tetrakisphosphate + ADP + 2 H(+).	tmpzr1t_l9r_go_relaxed.owl	IP3 3-kinase activity|1D-myo-inositol-trisphosphate 3-kinase activity|inositol trisphosphate 3-kinase activity|ATP:1D-myo-inositol-1,4,5-trisphosphate 3-phosphotransferase activity|Ins(1,4,5)P3 3-kinase activity|inositol-trisphosphate 3-kinase activity|IP3K activity|ins(1,4,5)P(3) 3-kinase activity				Reactome:R-HSA-1855153|RHEA:11020|MetaCyc:2.7.1.127-RXN|Reactome:R-HSA-1855233|KEGG_REACTION:R03433|EC:2.7.1.127									molecular_function											owl:Class	
GO:0047983	biolink:NamedThing	homoglutathione synthase activity	Catalysis of the reaction: beta-alanine + L-gamma-glutamyl-L-cysteine + ATP = gamma-L-glutamyl-L-cysteinyl-beta-alanine + ADP + 2 H(+) + phosphate.	tmpzr1t_l9r_go_relaxed.owl	homoglutathione synthetase activity|beta-alanine specific hGSH synthetase activity|gamma-L-glutamyl-L-cysteine:beta-alanine ligase (ADP-forming)				MetaCyc:HOMOGLUTATHIONE-SYNTHASE-RXN|RHEA:17993|KEGG_REACTION:R02741|EC:6.3.2.23									molecular_function											owl:Class	
GO:1990439	biolink:NamedThing	MAP kinase serine/threonine phosphatase activity	Catalysis of the reaction: MAP kinase threonine phosphate + H2O = MAP kinase threonine + phosphate and MAP kinase serine phosphate + H2O = MAP kinase serine + phosphate.	tmpzr1t_l9r_go_relaxed.owl								al	2014-07-31T12:21:04Z					molecular_function											owl:Class	
GO:1903824	biolink:NamedThing	negative regulation of telomere single strand break repair	Any process that stops, prevents or reduces the frequency, rate or extent of telomere single strand break repair.	tmpzr1t_l9r_go_relaxed.owl	down regulation of telomere single-strand break repair|downregulation of telomere SSBR|inhibition of telomere single strand break repair|inhibition of single strand break repair in telomere|down-regulation of single strand break repair in telomere|downregulation of telomeric single strand break repair|down-regulation of telomeric single strand break repair|inhibition of telomere single-strand break repair|inhibition of telomere SSBR|down regulation of telomere SSBR|inhibition of telomeric single strand break repair|downregulation of single strand break repair in telomere|negative regulation of telomere single-strand break repair|negative regulation of telomeric single strand break repair|downregulation of telomere single-strand break repair|down-regulation of telomere single strand break repair|down regulation of telomere single strand break repair|down regulation of single strand break repair in telomere|down-regulation of telomere single-strand break repair|negative regulation of telomere SSBR|downregulation of telomere single strand break repair|down regulation of telomeric single strand break repair|down-regulation of telomere SSBR|negative regulation of single strand break repair in telomere							jl	2015-01-19T16:24:37Z					biological_process											owl:Class	
GO:0018549	biolink:NamedThing	methanethiol oxidase activity	Catalysis of the reaction: methanethiol + O2 + H2O = formaldehyde + hydrogen sulfide + hydrogen peroxide.	tmpzr1t_l9r_go_relaxed.owl	(MM)-oxidase activity|methanethiol:oxygen oxidoreductase activity|methylmercaptan oxidase activity|MT-oxidase activity|methyl mercaptan oxidase activity				RHEA:11812|MetaCyc:METHANETHIOL-OXIDASE-RXN|UM-BBD_reactionID:r0209|EC:1.8.3.4									molecular_function											owl:Class	
GO:1990536	biolink:NamedThing	phosphoenolpyruvate transmembrane import into Golgi lumen	The directed movement of phosphoenolpyruvate into the Golgi lumen across the Golgi membrane.	tmpzr1t_l9r_go_relaxed.owl								vw	2014-11-14T10:17:01Z					biological_process											owl:Class	
GO:0055036	biolink:NamedThing	virion membrane	The lipid bilayer surrounding a virion.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0097147	biolink:NamedThing	NOXA-BCL-2 complex	A heterodimeric protein complex consisting of NOXA and BCL-2, members of the Bcl-2 family of anti- and proapoptotic regulators.	tmpzr1t_l9r_go_relaxed.owl								pr	2011-08-02T01:50:14Z					cellular_component											owl:Class	
GO:0043842	biolink:NamedThing	Kdo transferase activity	Catalysis of the reactions: (KDO)-lipid IVA + CMP-3-deoxy-D-manno-octulosonate = KDO2-lipid IVA + CMP, and lipid IVA + CMP-3-deoxy-D-manno-octulosonate = (KDO)-lipid IVA + CMP.	tmpzr1t_l9r_go_relaxed.owl	3-deoxy-D-manno-octulosonic-acid transferase activity|kdtA|WaaA				EC:2.4.99.13|EC:2.4.99.12|EC:2.4.99.15|EC:2.4.99.14|MetaCyc:KDOTRANS-RXN|MetaCyc:KDOTRANS2-RXN									molecular_function											owl:Class	
GO:0046706	biolink:NamedThing	CDP catabolic process	The chemical reactions and pathways resulting in the breakdown of CDP, cytidine (5'-)diphosphate.	tmpzr1t_l9r_go_relaxed.owl	CDP breakdown|CDP degradation|CDP catabolism													biological_process											owl:Class	
GO:1990767	biolink:NamedThing	prostaglandin receptor internalization	The process that results in the uptake of a prostaglandin receptor into an endocytic vesicle.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-06-10T19:14:08Z					biological_process											owl:Class	
GO:0045173	biolink:NamedThing	O-sialoglycoprotein catabolic process	The chemical reactions and pathways resulting in the breakdown of O-sialoglycoproteins, glycoproteins which contain sialic acid as one of their carbohydrates. They are often found on or in the cell or tissue membranes and participate in a variety of biological activities.	tmpzr1t_l9r_go_relaxed.owl	O-sialoglycoprotein breakdown|O-sialoglycoprotein catabolism|O-sialoglycoprotein degradation													biological_process											owl:Class	
GO:0035792	biolink:NamedThing	host cell postsynaptic membrane	A postsynaptic membrane that is part of a host cell. A postsynaptic membrane is a specialized area of membrane facing the presynaptic membrane on the tip of the nerve ending and separated from it by a minute cleft (the synaptic cleft). Neurotransmitters transmit the signal across the synaptic cleft to the postsynaptic membrane.	tmpzr1t_l9r_go_relaxed.owl	other organism postsynaptic membrane|other organism post-synaptic membrane							bf	2011-04-08T01:21:20Z					cellular_component											owl:Class	
GO:0031040	biolink:NamedThing	micronucleus	A membrane-bounded organelle of ciliated protozoan cells that contains a diploid copy of the cell's complete genome. Sections of contiguous sequence in the macronucleus are often interrupted by internal eliminated sequences (IES), and may be permuted, in micronuclei. Genic transcription is not found in micronuclei. Some ciliate species may contain multiple micronuclei per cell.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Micronucleus									cellular_component											owl:Class	
GO:0002354	biolink:NamedThing	central B cell negative selection	Any process leading to negative selection of B cells in the bone marrow.	tmpzr1t_l9r_go_relaxed.owl	central B lymphocyte negative selection|central B-lymphocyte negative selection|central B-cell negative selection													biological_process											owl:Class	
GO:0047933	biolink:NamedThing	glucose-1,6-bisphosphate synthase activity	Catalysis of the reaction: 3-phospho-D-glyceroyl phosphate + alpha-D-glucose 1-phosphate = 3-phospho-D-glycerate + alpha-D-glucose 1,6-bisphosphate + H(+).	tmpzr1t_l9r_go_relaxed.owl	3-phospho-D-glyceroyl-phosphate:D-glucose-1-phosphate 6-phosphotransferase activity|glucose-1,6-bisphosphate synthetase activity|glucose 1,6-diphosphate synthase activity|3-phospho-D-glyceroyl-phosphate:alpha-D-glucose-1-phosphate 6-phosphotransferase activity				EC:2.7.1.106|RHEA:16769|Reactome:R-HSA-8955760|KEGG_REACTION:R01660|MetaCyc:GLUCOSE-16-BISPHOSPHATE-SYNTHASE-RXN									molecular_function											owl:Class	
GO:0090403	biolink:NamedThing	oxidative stress-induced premature senescence	A cellular senescence process associated with the dismantling of a cell as a response to oxidative stress, e.g. high levels of reactive oxygen species, such as superoxide anions, hydrogen peroxide, and hydroxyl radicals.	tmpzr1t_l9r_go_relaxed.owl								tb	2011-01-05T02:37:57Z					biological_process											owl:Class	
GO:0090400	biolink:NamedThing	stress-induced premature senescence	A cellular senescence process associated with the dismantling of a cell as a response to environmental factors such as hydrogen peroxide or X-rays.	tmpzr1t_l9r_go_relaxed.owl	SIPS							tb	2011-01-05T02:32:29Z					biological_process											owl:Class	
GO:0000454	biolink:NamedThing	snoRNA guided rRNA pseudouridine synthesis	The intramolecular conversion of uridine to pseudouridine in an rRNA molecule during ribosome biogenesis using a snoRNA guide that targets the position of pseudouridylation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0031118	biolink:NamedThing	rRNA pseudouridine synthesis	The intramolecular conversion of uridine to pseudouridine in an rRNA molecule.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0010282	biolink:NamedThing	senescence-associated vacuole	A lytic vacuole that is maintained at acidic pH and has different tonoplast composition compared to the central vacuole. Found during leaf senescence and develops in the peripheral cytoplasm of cells that contain chloroplast.	tmpzr1t_l9r_go_relaxed.owl	senescence associated vacuole													cellular_component											owl:Class	
GO:0047061	biolink:NamedThing	glucose-fructose oxidoreductase activity	Catalysis of the reaction: D-fructose + D-glucose = D-glucitol + D-glucono-1,5-lactone.	tmpzr1t_l9r_go_relaxed.owl	D-glucose:D-fructose oxidoreductase activity				EC:1.1.99.28|MetaCyc:1.1.99.28-RXN|KEGG_REACTION:R00874|RHEA:20637									molecular_function											owl:Class	
GO:0030332	biolink:NamedThing	cyclin binding	Binding to cyclins, proteins whose levels in a cell varies markedly during the cell cycle, rising steadily until mitosis, then falling abruptly to zero. As cyclins reach a threshold level, they are thought to drive cells into G2 phase and thus to mitosis.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0047804	biolink:NamedThing	cysteine-S-conjugate beta-lyase activity	Catalysis of the reaction: RS-CH2-CH(NH3+)COO- = RSH + NH3 + pyruvate.	tmpzr1t_l9r_go_relaxed.owl	glutamine transaminase K/cysteine conjugate beta-lyase activity|cysteine-S-conjugate b-lyase activity|L-cysteine-S-conjugate thiol-lyase (deaminating) activity|cysteine conjugate beta-lyase activity|L-cysteine-S-conjugate thiol-lyase (deaminating; pyruvate-forming)				EC:4.4.1.13|MetaCyc:CYSTEINE-S-CONJUGATE-BETA-LYASE-RXN|RHEA:18121									molecular_function											owl:Class	
GO:1904902	biolink:NamedThing	ESCRT III complex assembly	The aggregation, arrangement and bonding together of a set of components to form an ESCRT III complex.	tmpzr1t_l9r_go_relaxed.owl	ESCRT III complex formation							pad	2016-01-18T13:38:07Z					biological_process											owl:Class	
GO:1904895	biolink:NamedThing	ESCRT complex assembly	The aggregation, arrangement and bonding together of a set of components to form an ESCRT complex.	tmpzr1t_l9r_go_relaxed.owl	ESCRT complex formation|endosomal sorting complex required for transport formation|endosomal sorting complex required for transport assembly							pad	2016-01-12T10:27:11Z					biological_process											owl:Class	
GO:0097572	biolink:NamedThing	right nucleus	One of the two nuclei found in Giardia species (trophozoite stage). It is located on the right side of the cell when viewed from the dorsal side.	tmpzr1t_l9r_go_relaxed.owl						Due to the asymmetric nature of the Giardia trophozoite, this term is defined spatially as the trophozoite is viewed from the dorsal side, with the two nuclei dorsal to the ventral disc, and the ventral disc toward the anterior.		pr	2014-02-18T11:23:01Z					cellular_component											owl:Class	
GO:0060843	biolink:NamedThing	venous endothelial cell differentiation	The process in which a relatively unspecialized endothelial cell acquires specialized features of a venous endothelial cell, a thin flattened cell that lines the inside surfaces of veins.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-08-12T10:43:40Z					biological_process											owl:Class	
GO:0050472	biolink:NamedThing	zeatin reductase activity	Catalysis of the reaction: dihydrozeatin + NADP(+) = H(+) + NADPH + zeatin.	tmpzr1t_l9r_go_relaxed.owl	dihydrozeatin:NADP+ oxidoreductase activity				KEGG_REACTION:R05702|EC:1.3.1.69|RHEA:12757|MetaCyc:ZEATIN-REDUCTASE-RXN									molecular_function											owl:Class	
GO:0007168	biolink:NamedThing	receptor guanylyl cyclase signaling pathway	A series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell where the receptor possesses guanylyl cyclase activity, and ending with regulation of a downstream cellular process, e.g. transcription.	tmpzr1t_l9r_go_relaxed.owl	receptor guanylyl cyclase signalling pathway													biological_process											owl:Class	
GO:0070644	biolink:NamedThing	vitamin D response element binding	Binding to a vitamin D response element (VDRE), a short sequence with dyad symmetry found in the promoters of some of the cellular immediate-early genes, regulated by serum.	tmpzr1t_l9r_go_relaxed.owl	VDRE binding					Note that as agreed during the transcription overhaul, terms specifying binding to specific transcription regulatory motifs are no longer being created. The level of specificity GO has decided to go to is the "core promoter", "core promoter proximal region" and "enhancer". To capture more detail, please consider using column 16.		mah	2009-05-08T04:23:44Z					molecular_function											owl:Class	
GO:0103099	biolink:NamedThing	UDP-glucose:5-methylthiopentylhydroximate S-glucosyltransferase activity	Catalysis of the reaction: UDP-alpha-D-glucose + 5-methylthiopentylhydroximate <=> H+ + 4-methylthiobutyldesulfoglucosinolate + UDP.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXNQT-4324|EC:2.4.1.195									molecular_function											owl:Class	
GO:0017147	biolink:NamedThing	Wnt-protein binding	Binding to a Wnt-protein, a secreted growth factor involved in signaling.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0050044	biolink:NamedThing	galactose-6-phosphate isomerase activity	Catalysis of the reaction: D-galactose 6-phosphate = D-tagatose 6-phosphate.	tmpzr1t_l9r_go_relaxed.owl	D-galactose-6-phosphate aldose-ketose-isomerase activity|D-galactose-6-phosphate ketol-isomerase activity				MetaCyc:LACTOSE-6-PHOSPHATE-ISOMERASE-RXN|KEGG_REACTION:R03240|EC:5.3.1.26|RHEA:13033									molecular_function											owl:Class	
GO:0031402	biolink:NamedThing	sodium ion binding	Binding to a sodium ion (Na+).	tmpzr1t_l9r_go_relaxed.owl	Na+ ion binding													molecular_function											owl:Class	
GO:0102483	biolink:NamedThing	scopolin beta-glucosidase activity	Catalysis of the reaction: H2O + scopolin <=> beta-D-glucose + scopoletin.	tmpzr1t_l9r_go_relaxed.owl					EC:3.2.1.21|MetaCyc:RXN-14179									molecular_function											owl:Class	
GO:0070448	biolink:NamedThing	laricitrin 5'-O-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + laricitrin = S-adenosyl-L-homocysteine + syringetin.	tmpzr1t_l9r_go_relaxed.owl	flavonoid 3',5'-O-dimethyltransferase activity|S-adenosyl-L-methionine:myricetin O-methyltransferase activity|CrCOMT2				MetaCyc:RXN-8452|EC:2.1.1.267|RHEA:25633|KEGG_REACTION:R06816	Note that this term represents one of two reactions that are grouped together in EC:2.1.1.267.								molecular_function											owl:Class	
GO:0140363	biolink:NamedThing	TIS granule	A ribonucleoprotein granule located in the cytoplasm that is formed by the RNA-binding protein TIS11B and RNA molecules, enriched in membrane protein-encoding mRNAs with multiple AU-rich elements. TIS granules are reticular meshworks intertwined with the endoplasmic reticulum (ER).	tmpzr1t_l9r_go_relaxed.owl								pg	2019-07-25T19:20:58Z					cellular_component											owl:Class	
GO:0043843	biolink:NamedThing	ADP-specific glucokinase activity	Catalysis of the reaction: ADP + D-glucose = AMP + D-glucose 6-phosphate.	tmpzr1t_l9r_go_relaxed.owl	ADP-dependent glucokinase activity|ADP:D-glucose 6-phosphotransferase activity				Reactome:R-HSA-5696021|RHEA:11460|EC:2.7.1.147									molecular_function											owl:Class	
GO:0048851	biolink:NamedThing	hypophysis formation	The process in which the anatomical structures of the hypophysis are generated and organized. The hypophysis is an endocrine gland that secretes hormones that regulate many other glands.	tmpzr1t_l9r_go_relaxed.owl	pituitary gland formation|pituitary gland biosynthesis|hypophysis biosynthesis													biological_process											owl:Class	
GO:0038095	biolink:NamedThing	Fc-epsilon receptor signaling pathway	A series of molecular signals initiated by the binding of the Fc portion of immunoglobulin E (IgE) to an Fc-epsilon receptor on the surface of a signal-receiving cell, and ending with regulation of a downstream cellular process, e.g. transcription. The Fc portion of an immunoglobulin is its C-terminal constant region.	tmpzr1t_l9r_go_relaxed.owl	Fc-epsilon receptor signalling pathway							bf	2012-02-16T05:23:51Z					biological_process											owl:Class	
GO:1990088	biolink:NamedThing	[methyl-Co(III) methanol-specific corrinoid protein]:coenzyme M methyltransferase activity	Catalysis of the reaction: a [methyl-Co(III) methanol-specific corrinoid protein] + coenzyme M = methyl-CoM + a [Co(I) methanol-specific corrinoid protein].	tmpzr1t_l9r_go_relaxed.owl					EC:2.1.1.246|RHEA:45208			hjd	2013-05-06T15:07:20Z					molecular_function											owl:Class	
GO:0031805	biolink:NamedThing	type 8 metabotropic glutamate receptor binding	Binding to a type 8 metabotropic glutamate receptor.	tmpzr1t_l9r_go_relaxed.owl	type 8 metabotropic glutamate receptor ligand													molecular_function											owl:Class	
GO:0071446	biolink:NamedThing	cellular response to salicylic acid stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a salicylic acid stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to salicylate stimulus							mah	2009-12-16T04:14:16Z					biological_process											owl:Class	
GO:0030721	biolink:NamedThing	spectrosome organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the spectrosome, a germline specific spherical organelle that is the precursor to the fusome.	tmpzr1t_l9r_go_relaxed.owl	spectrosome organization and biogenesis|spectrosome organisation													biological_process											owl:Class	
GO:1990006	biolink:NamedThing	amorphous vesicle	A cytoplasmic membrane-bounded vesicle first described in dendrites, categorized by smooth membranes, electron-lucent interiors and irregular shapes. Sometimes occurs in clumps. Amorphous vesicles have been found to contain material taken up from the extracellular space, therefore suggesting that they may be part of the endosomal pathway.	tmpzr1t_l9r_go_relaxed.owl					NIF_Subcellular:sao1531915298			pr	2012-12-11T14:55:36Z					cellular_component											owl:Class	
GO:0033679	biolink:NamedThing	3'-5' DNA/RNA helicase activity	Unwinding of a DNA/RNA duplex in the 3' to 5' direction, driven by ATP hydrolysis.	tmpzr1t_l9r_go_relaxed.owl	ATP-dependent 3' to 5' DNA/RNA helicase activity|ATP-dependent 3'-5' DNA/RNA helicase activity|3' to 5' DNA/RNA helicase activity	https://github.com/geneontology/go-ontology/issues/21612										GO:0033681		molecular_function											owl:Class	
GO:0061497	biolink:NamedThing	inner plaque of mitotic spindle pole body	One of three laminate structures that form the mitotic spindle pole body; the inner plaque is in the nucleus.	tmpzr1t_l9r_go_relaxed.owl								dph	2012-12-11T09:15:12Z					cellular_component											owl:Class	
GO:0099105	biolink:NamedThing	ion channel modulating, G protein-coupled receptor signaling pathway	The series of molecular signals generated as a consequence of a G protein-coupled receptor binding to its physiological ligand, where the pathway proceeds through activation or inhibition of an ion channel.	tmpzr1t_l9r_go_relaxed.owl	ion channel modulating, G-protein coupled receptor signaling pathway													biological_process											owl:Class	
GO:0050133	biolink:NamedThing	N6-hydroxylysine O-acetyltransferase activity	Catalysis of the reaction: N(6)-hydroxy-L-lysine + acetyl-CoA = N(6)-acetyl-N(6)-hydroxy-L-lysine + CoA.	tmpzr1t_l9r_go_relaxed.owl	N6-hydroxylysine:acetyl CoA N6-transacetylase activity|acetyl-CoA:N6-hydroxy-L-lysine 6-acetyltransferase activity|acetyl-CoA:6-N-hydroxy-L-lysine 6-acetyltransferase activity|N(6)-hydroxylysine acetylase activity|N6-hydroxylysine acetylase activity				MetaCyc:N6-HYDROXYLYSINE-O-ACETYLTRANSFERASE-RXN|KEGG_REACTION:R03168|EC:2.3.1.102|RHEA:22388									molecular_function											owl:Class	
GO:0098624	biolink:NamedThing	3'-phosphoadenylylselenate reductase activity	Catalysis of the reaction: 3'-phosphoadenylylselenate + NADPH => adenosine 3',5'-bisphosphate + selenite + NADP+ + H+.	tmpzr1t_l9r_go_relaxed.owl	PAPSe reductase activity				Reactome:R-HSA-2408548									molecular_function											owl:Class	
GO:1902141	biolink:NamedThing	cellular response to inositol	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an inositol stimulus.	tmpzr1t_l9r_go_relaxed.owl								al	2013-05-21T13:42:15Z					biological_process											owl:Class	
GO:0099609	biolink:NamedThing	microtubule lateral binding	Binding to the side of a microtubule.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0103091	biolink:NamedThing	2-(7'-methylthio)heptylmalate synthase activity	Catalysis of the reaction: 2-oxo-9-methylthiononanoate + acetyl-CoA + H2O <=> H+ + 2-(7'-methylthio)heptylmalate + coenzyme A.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXNQT-4175									molecular_function											owl:Class	
GO:0039560	biolink:NamedThing	suppression by virus of host JAK-STAT cascade via inhibition of host IRF9 activity	Any process in which a virus stops, prevents, or reduces a JAK1-STAT signaling cascade in a host organism by reducing the activity of host IRF9 (interferon regulatory factor-9), a transcription factor involved in the innate immune response. Viral infection triggers binding of IRF9 to phosphorylated STAT1 and STAT2, forming the ISGF3 complex. The ISGF3 complex migrates to the nucleus and activates transcription of IFN-responsive genes.	tmpzr1t_l9r_go_relaxed.owl	suppression by virus of host interferon regulatory factor 9 activity|suppression by virus of host IRF9 activity|inhibition of host IRF9 by virus|inhibition of host interferon regulatory factor-9 by virus	https://github.com/geneontology/go-ontology/issues/21986				This term is for annotation of viral proteins that counteract the host anti-viral innate immune response.		bf	2012-03-09T04:42:08Z					biological_process											owl:Class	
GO:0047179	biolink:NamedThing	platelet-activating factor acetyltransferase activity	Catalysis of the reaction: 1-radyl-2-acyl-sn-glycero-3-phospholipid + 1-alkyl-2-acetyl-sn-glycero-3-phosphocholine = 1-alkyl-2-lyso-sn-glycero-3-phosphocholine + 1-radyl-2-acetyl-sn-glycero-3-phospholipid.	tmpzr1t_l9r_go_relaxed.owl	PAF acetyltransferase activity|1-alkyl-2-acyl-sn-glycero-3-phosphocholine:1-organyl-2-lyso-sn-glycero-3-phospholipid acetyltransferase activity				MetaCyc:2.3.1.149-RXN|EC:2.3.1.149|RHEA:11048									molecular_function											owl:Class	
GO:0051482	biolink:NamedThing	positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway	Any process that increases the concentration of calcium ions in the cytosol that occurs as part of a PLC-activating G protein-coupled receptor signaling pathway. G-protein-activated PLC hydrolyses phosphatidylinositol-bisphosphate (PIP2) to release diacylglycerol (DAG) and inositol trisphosphate (IP3). IP3 then binds to calcium release channels in the endoplasmic reticulum (ER) to trigger calcium ion release into the cytosol.	tmpzr1t_l9r_go_relaxed.owl	elevation of cytosolic calcium ion concentration during G-protein signalling, coupled to IP3 second messenger (phospholipase C activating)|elevation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway|positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway|elevation of calcium ion concentration in cytosol during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)|elevation of cytoplasmic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)|elevation of cytoplasmic calcium ion concentration during G-protein signalling, coupled to IP3 second messenger (phospholipase C activating)|elevation of calcium ion concentration in cytoplasm during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)|elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger													biological_process											owl:Class	
GO:0044317	biolink:NamedThing	rod spherule	A specialized neuron projection which is the site of synaptic transmission produced by retinal rod cells. Rod spherules are small round enlargements of the axon (3-5 micrometers diameter) or even extensions of the cell body.	tmpzr1t_l9r_go_relaxed.owl	rod cell spherule|rod photoreceptor spherule							jl	2010-07-14T01:38:07Z					cellular_component											owl:Class	
GO:0040004	biolink:NamedThing	collagen and cuticulin-based cuticle attachment to epithelium	Attaching of a collagen and cuticulin-based cuticle to the epithelium underlying it. An example of this process is found in Caenorhabditis elegans.	tmpzr1t_l9r_go_relaxed.owl	cuticular attachment to epithelium													biological_process											owl:Class	
GO:0047322	biolink:NamedThing	[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity	Catalysis of the reaction: [3-hydroxy-3-methylglutaryl-CoA reductase (NADPH)] + ATP = [3-hydroxy-3-methylglutaryl-CoA reductase (NADPH)] phosphate + ADP.	tmpzr1t_l9r_go_relaxed.owl	hydroxymethylglutaryl coenzyme A reductase kinase (phosphorylating) activity|AMPK|reductase kinase activity|hydroxymethylglutaryl-CoA reductase (NADPH) kinase activity|ATP:hydroxymethylglutaryl-CoA reductase (NADPH) phosphotransferase activity|3-hydroxy-3-methylglutaryl coenzyme A reductase kinase activity|3-hydroxy-3-methylglutaryl-CoA reductase kinase activity|hydroxymethylglutaryl-CoA reductase (NADPH2) kinase activity|STK29|HMG-CoA reductase kinase activity|hydroxymethylglutaryl coenzyme A reductase kinase activity|beta-hydroxy-beta-methylglutaryl-CoA reductase kinase activity|hydroxymethylglutaryl-CoA reductase kinase activity				EC:2.7.11.31|RHEA:23172|MetaCyc:2.7.1.109-RXN									molecular_function											owl:Class	
GO:0097473	biolink:NamedThing	retinal rod cell apoptotic process	Any apoptotic process in a retinal rod cell, one of the two photoreceptor cell types of the vertebrate retina.	tmpzr1t_l9r_go_relaxed.owl	rod photoreceptor apoptotic process							pr	2013-03-21T09:44:45Z					biological_process											owl:Class	
GO:0047611	biolink:NamedThing	acetylspermidine deacetylase activity	Catalysis of the reaction: N(8)-acetylspermidine + H(2)O = acetate + spermidine.	tmpzr1t_l9r_go_relaxed.owl	N(1)-acetylspermidine amidohydrolase activity|N8-acetylspermidine amidohydrolase activity|N(8)-acetylspermidine deacetylase activity|8-N-acetylspermidine amidohydrolase activity|N1-acetylspermidine amidohydrolase activity|N(8)-monoacetylspermidine deacetylase activity|N(8)-acetylspermidine amidohydrolase activity|N8-acetylspermidine deacetylase activity|N8-monoacetylspermidine deacetylase activity|N-acetylspermidine deacetylase activity				KEGG_REACTION:R07300|RHEA:23928|MetaCyc:ACETYLSPERMIDINE-DEACETYLASE-RXN|EC:3.5.1.48									molecular_function											owl:Class	
GO:0034578	biolink:NamedThing	limonene 8-hydratase activity	Catalysis of the reaction: limonene + H2O = alpha-terpineol.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0916									molecular_function											owl:Class	
GO:0045498	biolink:NamedThing	sex comb development	The process whose specific outcome is the progression of the sex comb over time, from its formation to the mature structure. The sex combs are the male specific chaetae located on the prothoracic tarsal segment of the prothoracic leg.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0140482	biolink:NamedThing	iron sensor activity	Binding to and responding, e.g. by conformational change, to changes in the cellular level of iron.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/19433						pg	2020-06-25T20:58:02Z					molecular_function											owl:Class	
GO:0007491	biolink:NamedThing	sternite morphogenesis	The process in which the anatomical structures of the sternite are generated and organized. The sternite is the plate or sclerite on the underside of a body segment.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0002179	biolink:NamedThing	homodimeric serine palmitoyltransferase complex	A homodimeric complex which transfers a palmitoyl group onto serine, forming 3-dehydro-D-sphinganine.	tmpzr1t_l9r_go_relaxed.owl						This complex occurs primarily in bacteria.		hjd	2010-12-03T10:50:59Z					cellular_component											owl:Class	
GO:0071136	biolink:NamedThing	alpha7-beta1 integrin-laminin alpha-2 complex	A protein complex that consists of an alpha7-beta1 integrin complex bound to laminin alpha-2.	tmpzr1t_l9r_go_relaxed.owl	ITGA7-ITGB1-LAMA2 complex							mah	2009-11-13T02:29:42Z					cellular_component											owl:Class	
GO:0048407	biolink:NamedThing	platelet-derived growth factor binding	Binding to platelet-derived growth factor.	tmpzr1t_l9r_go_relaxed.owl	PDGF binding													molecular_function											owl:Class	
GO:0052585	biolink:NamedThing	oxidoreductase activity, acting on the CH-NH2 group of donors, with a quinone or similar compound as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH2 group acts as a hydrogen or electron donor and reduces a quinone or similar compound.	tmpzr1t_l9r_go_relaxed.owl					EC:1.4.5.-				2010-08-13T10:29:06Z					molecular_function											owl:Class	
GO:0047196	biolink:NamedThing	long-chain-alcohol O-fatty-acyltransferase activity	Catalysis of the reaction: a long-chain-alcohol + acyl-CoA = a long-chain ester + CoA.	tmpzr1t_l9r_go_relaxed.owl	wax ester synthase activity|wax-ester synthase activity|acyl-CoA:long-chain-alcohol O-acyltransferase activity|wax synthase activity				Reactome:R-HSA-5696424|MetaCyc:RXNQT-4193|RHEA:38443|Reactome:R-HSA-8848582|EC:2.3.1.75|MetaCyc:2.3.1.75-RXN							GO:0103095		molecular_function											owl:Class	
GO:0031934	biolink:NamedThing	mating-type region heterochromatin	Heterochromatic regions of the chromosome found at silenced mating-type loci.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0004164	biolink:NamedThing	diphthine synthase activity	Catalysis of the reaction: S-adenosyl-L-methionine + 2-(3-carboxy-3-aminopropyl)-L-histidine = S-adenosyl-L-homocysteine + 2-(3-carboxy-3-(methylammonio)propyl)-L-histidine.	tmpzr1t_l9r_go_relaxed.owl	diphthine methyltransferase activity|S-adenosyl-L-methionine:2-(3-carboxy-3-aminopropyl)-L-histidine methyltransferase activity|S-adenosyl-L-methionine:elongation factor 2 methyltransferase activity				EC:2.1.1.98|MetaCyc:RXN-11370|RHEA:36415|Reactome:R-HSA-5358484									molecular_function											owl:Class	
GO:0033038	biolink:NamedThing	bitter taste receptor activity	Combining with soluble bitter compounds to initiate a change in cell activity. These receptors are responsible for the sense of bitter taste.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1990062	biolink:NamedThing	RPAP3/R2TP/prefoldin-like complex	A protein complex first characterized in human and comprised of a R2TP module (R2TP complex), a prefoldin-like module (containing both prefoldin-like proteins and canonical prefoldins), WD40 repeat protein Monad/WDR92 and DNA-dependent RNA polymerase subunit RPB5. This complex might have chaperone activity.	tmpzr1t_l9r_go_relaxed.owl	R2TP/prefoldin-like complex							pr	2013-03-20T15:31:12Z					cellular_component											owl:Class	
GO:0046702	biolink:NamedThing	galactoside 6-L-fucosyltransferase activity	Catalysis of the transfer of an L-fucosyl group from GDP-beta-L-fucose to a galactoside acceptor molecule, usually an N-glycan, to form an alpha(1,6)-fucosylated galactoside.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1990115	biolink:NamedThing	RNA polymerase III assembly	The aggregation, arrangement and bonding together of a set of components to form the eukaryotic RNA polymerase III complex.	tmpzr1t_l9r_go_relaxed.owl	RNA Polymerase III complex assembly|DNA-directed RNA polymerase III complex assembly							rb	2013-05-31T21:49:19Z					biological_process											owl:Class	
GO:0046507	biolink:NamedThing	UDPsulfoquinovose synthase activity	Catalysis of the reaction: sulfite + UDP-D-glucose = H(2)O + UDP-6-sulfoquinovose.	tmpzr1t_l9r_go_relaxed.owl	UDP-6-sulfo-6-deoxyglucose sulfohydrolase activity|UDP-sulfoquinovose synthase activity|UDPsulphoquinovose synthase activity|sulfite:UDP-glucose sulfotransferase activity				MetaCyc:RXN-1223|EC:3.13.1.1|KEGG_REACTION:R05775|RHEA:13197									molecular_function											owl:Class	
GO:0071796	biolink:NamedThing	K6-linked polyubiquitin modification-dependent protein binding	Binding to a protein upon poly-ubiquitination formed by linkages between lysine residues at position 6 in the target protein.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-09-02T02:13:07Z					molecular_function											owl:Class	
GO:1990199	biolink:NamedThing	MsbA transporter complex	An ATP-binding cassette (ABC) transporter complex made up of a dimer of MsbA. Facilitates the export across the plasma membrane of, amongst others, lipid A and lipopolysaccharide. In contrast to most ABC transporter complexes, each chain of the homodimer contains both the transmembrane domain (TMD) and the cytoplasmic ATP-binding domain (NBD).	tmpzr1t_l9r_go_relaxed.owl	MsbA complex|MsbA dimer							bhm	2013-10-01T07:49:41Z					cellular_component											owl:Class	
GO:0072373	biolink:NamedThing	alpha-carotene epsilon hydroxylase activity	Catalysis of the reaction: alpha-carotene + NADPH + O2 + H+ = alpha-cryptoxanthin + NADP+ + H2O.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-11-19T03:52:25Z					molecular_function											owl:Class	
GO:0043883	biolink:NamedThing	malolactic enzyme activity	Catalysis of the reaction: malate + H+ = L-lactate + CO2.	tmpzr1t_l9r_go_relaxed.owl	MleS					This function is part of the process of degradation of L-malic acid by lactic acid bacteria.								molecular_function											owl:Class	
GO:0047281	biolink:NamedThing	dioxotetrahydropyrimidine phosphoribosyltransferase activity	Catalysis of the reaction: pyrophosphate + a 2,4-dioxotetrahydropyrimidine D-ribonucleotide = PRPP + a 2,4-dioxotetrahydropyrimidine.	tmpzr1t_l9r_go_relaxed.owl	dioxotetrahydropyrimidine-ribonucleotide diphosphorylase activity|2,4-dioxotetrahydropyrimidine-nucleotide:diphosphate phospho-alpha-D-ribosyltransferase activity|dioxotetrahydropyrimidine-ribonucleotide pyrophosphorylase activity|dioxotetrahydropyrimidine phosphoribosyl transferase activity|dioxotetrahydropyrimidine ribonucleotide pyrophosphorylase activity				EC:2.4.2.20|RHEA:10232|MetaCyc:2.4.2.20-RXN									molecular_function											owl:Class	
GO:0018582	biolink:NamedThing	1-hydroxy-2-naphthoate 1,2-dioxygenase activity	Catalysis of the reaction: 1-hydroxy-2-naphthoate + O2 = (3E)-4-(2-carboxyphenyl)-2-oxobut-3-enoate.	tmpzr1t_l9r_go_relaxed.owl	1-hydroxy-2-naphthoate:oxygen 1,2-oxidoreductase (decyclizing)|1-hydroxy-2-naphthoic acid dioxygenase activity|1-hydroxy-2-naphthoate dioxygenase activity|1-hydroxy-2-naphthoate-degrading enzyme activity				MetaCyc:1.13.11.38-RXN|UM-BBD_reactionID:r0486|RHEA:14749|EC:1.13.11.38									molecular_function											owl:Class	
GO:0016290	biolink:NamedThing	palmitoyl-CoA hydrolase activity	Catalysis of the reaction: palmitoyl-CoA + H2O = CoA + palmitate.	tmpzr1t_l9r_go_relaxed.owl	palmityl-CoA deacylase activity|palmitoyl-CoA deacylase activity|palmitoyl coenzyme A hydrolase activity|long-chain fatty-acyl-CoA hydrolase activity|palmitoyl thioesterase activity|palmityl thioesterase activity|palmityl thioesterase I|fatty acyl thioesterase I				EC:3.1.2.2|RHEA:16645|MetaCyc:PALMITOYL-COA-HYDROLASE-RXN|MetaCyc:PWY-5148							GO:0016293		molecular_function											owl:Class	
GO:0030876	biolink:NamedThing	interleukin-20 receptor complex	A protein complex composed of an alpha and a beta receptor subunit and an interleukin ligand. In human, Interleukin-19, -20 and -24 bind IL20RA/IL20RB receptor subunits and Interleukin-20 and -24 bind IL22RA1/IL20RB receptor subunits.	tmpzr1t_l9r_go_relaxed.owl	IL-20 receptor complex													cellular_component											owl:Class	
GO:0015841	biolink:NamedThing	chromaffin granule amine transport	The directed movement of amines into, out of or within chromaffin granules.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1903359	biolink:NamedThing	lateral cortical node assembly	The aggregation, arrangement and bonding together of a set of components to form a lateral cortical node.	tmpzr1t_l9r_go_relaxed.owl	Skb1-containing cortical node formation|lateral cortical node formation|Skb1-containing cortical node assembly							mah	2014-08-21T10:22:51Z					biological_process											owl:Class	
GO:0033801	biolink:NamedThing	vitexin 2''-O-rhamnoside 7-O-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + vitexin 2''-O-beta-L-rhamnoside = S-adenosyl-L-homocysteine + 7-O-methylvitexin 2''-O-beta-L-rhamnoside.	tmpzr1t_l9r_go_relaxed.owl	S-adenosyl-L-methionine:vitexin-2''-O-beta-L-rhamnoside 7-O-methyltransferase activity				EC:2.1.1.153|RHEA:11432|MetaCyc:RXN-4981									molecular_function											owl:Class	
GO:0036042	biolink:NamedThing	long-chain fatty acyl-CoA binding	Binding to a long-chain fatty acyl-CoA, any derivative of coenzyme A in which the sulfhydryl group is in a thioester linkage with a long-chain fatty-acyl group. Long-chain fatty-acyl-CoAs have chain lengths of C13 or more.	tmpzr1t_l9r_go_relaxed.owl	long-chain fatty acyl-coenyme A binding	https://github.com/geneontology/go-ontology/issues/19443						bf	2011-11-24T04:31:09Z					molecular_function											owl:Class	
GO:0043829	biolink:NamedThing	tRNA-specific adenosine-37 deaminase activity	Catalysis of the reaction: adenosine-37 + H2O = inosine-37 + NH3, in a tRNA-Ala molecule.	tmpzr1t_l9r_go_relaxed.owl	TAD1|tRNA(Ala)-A37 deaminase activity|tRNA-specific adenosine deaminase 1													molecular_function											owl:Class	
GO:0047153	biolink:NamedThing	deoxycytidylate 5-hydroxymethyltransferase activity	Catalysis of the reaction: 5,10-methylenetetrahydrofolate + dCMP + H(2)O = (6S)-5,6,7,8-tetrahydrofolate + 5-hydroxymethyldeoxycytidylate.	tmpzr1t_l9r_go_relaxed.owl	deoxycytidylic hydroxymethylase activity|dCMP hydroxymethylase activity|d-cytidine 5'-monophosphate hydroxymethylase activity|5,10-methylenetetrahydrofolate:deoxycytidylate 5-hydroxymethyltransferase activity|deoxycytidylate hydroxymethyltransferase activity|deoxycytidylate hydroxymethylase activity|deoxyCMP hydroxymethylase activity				MetaCyc:2.1.2.8-RXN|KEGG_REACTION:R01669|EC:2.1.2.8|RHEA:11280									molecular_function											owl:Class	
GO:0045264	biolink:NamedThing	plasma membrane proton-transporting ATP synthase complex, coupling factor F(o)	All non-F1 subunits of the plasma membrane hydrogen-transporting ATP synthase, including integral and peripheral plasma membrane proteins.	tmpzr1t_l9r_go_relaxed.owl	proton-transporting ATP synthase complex, coupling factor F(o)|proton-transporting ATP synthase complex, coupling factor F(0)|hydrogen-transporting ATP synthase, F0 sector													cellular_component											owl:Class	
GO:1903554	biolink:NamedThing	G protein-coupled receptor signaling pathway involved in defense response to Gram-negative bacterium	Any G protein-coupled receptor signaling pathway that is involved in defense response to Gram-negative bacterium.	tmpzr1t_l9r_go_relaxed.owl	G-protein-coupled receptor protein signalling pathway involved in defense response to Gram-negative bacterium|G protein coupled receptor protein signalling pathway involved in defense response to Gram-negative bacterium|G-protein coupled receptor signalling pathway involved in defence response to Gram-negative bacterium|GPCR signalling pathway involved in Gram-negative antibacterial peptide activity|G protein coupled receptor protein signaling pathway involved in defense response to Gram-negative bacteria|G-protein-coupled receptor protein signalling pathway involved in Gram-negative antibacterial peptide activity|G-protein coupled receptor signalling pathway involved in defense response to Gram-negative bacterium|G protein coupled receptor protein signaling pathway involved in Gram-negative antibacterial peptide activity|GPCR signaling pathway involved in defense response to Gram-negative bacterium|G protein coupled receptor protein signalling pathway involved in defense response to Gram-negative bacteria|G-protein coupled receptor protein signaling pathway involved in defense response to Gram-negative bacterium|G-protein-coupled receptor protein signaling pathway involved in defence response to Gram-negative bacteria|G protein coupled receptor protein signaling pathway involved in defense response to Gram-negative bacterium|G-protein coupled receptor protein signaling pathway involved in defence response to Gram-negative bacteria|G-protein-coupled receptor protein signaling pathway involved in defence response to Gram-negative bacterium|G-protein coupled receptor protein signal transduction involved in defense response to Gram-negative bacteria|G-protein coupled receptor protein signal transduction involved in defence response to Gram-negative bacteria|GPCR signaling pathway involved in defense response to Gram-negative bacteria|G-protein coupled receptor protein signal transduction involved in defence response to Gram-negative bacterium|G protein coupled receptor protein signalling pathway involved in defence response to Gram-negative bacteria|G-protein-coupled receptor protein signalling pathway involved in defence response to Gram-negative bacterium|G-protein coupled receptor protein signal transduction involved in Gram-negative antibacterial peptide activity|GPCR signaling pathway involved in defence response to Gram-negative bacteria|G-protein coupled receptor protein signaling pathway involved in defence response to Gram-negative bacterium|G-protein coupled receptor protein signal transduction involved in defense response to Gram-negative bacterium|G-protein coupled receptor signaling pathway involved in Gram-negative antibacterial peptide activity|G-protein coupled receptor protein signaling pathway involved in Gram-negative antibacterial peptide activity|GPCR signalling pathway involved in defence response to Gram-negative bacterium|GPCR signaling pathway involved in Gram-negative antibacterial peptide activity|G-protein-coupled receptor protein signaling pathway involved in defense response to Gram-negative bacterium|G-protein coupled receptor protein signaling pathway involved in defense response to Gram-negative bacteria|G protein coupled receptor protein signaling pathway involved in defence response to Gram-negative bacterium|G protein coupled receptor protein signalling pathway involved in Gram-negative antibacterial peptide activity|G-protein coupled receptor signalling pathway involved in defense response to Gram-negative bacteria|G-protein-coupled receptor protein signalling pathway involved in defence response to Gram-negative bacteria|GPCR signaling pathway involved in defence response to Gram-negative bacterium|GPCR signalling pathway involved in defense response to Gram-negative bacterium|G-protein-coupled receptor protein signalling pathway involved in defense response to Gram-negative bacteria|GPCR signalling pathway involved in defence response to Gram-negative bacteria|G-protein coupled receptor signaling pathway involved in defence response to Gram-negative bacterium|G protein coupled receptor protein signaling pathway involved in defence response to Gram-negative bacteria|G-protein coupled receptor signalling pathway involved in Gram-negative antibacterial peptide activity|G-protein coupled receptor signaling pathway involved in defence response to Gram-negative bacteria|G-protein coupled receptor signaling pathway involved in defense response to Gram-negative bacteria|GPCR signalling pathway involved in defense response to Gram-negative bacteria|G-protein coupled receptor signalling pathway involved in defence response to Gram-negative bacteria|G-protein-coupled receptor protein signaling pathway involved in Gram-negative antibacterial peptide activity|G protein coupled receptor protein signalling pathway involved in defence response to Gram-negative bacterium							kmv	2014-10-20T17:51:13Z					biological_process											owl:Class	
GO:0061847	biolink:NamedThing	response to cholecystokinin	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cholecystokinin stimulus.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0140464	biolink:NamedThing	silent mating-type cassette heterochromatin organization	The organization of chromatin into heterochromatin at a silent mating-type cassette locus.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/19396						pg	2020-05-13T05:13:24Z					biological_process											owl:Class	
GO:0004307	biolink:NamedThing	ethanolaminephosphotransferase activity	Catalysis of the reaction: CDP-ethanolamine + 1,2-diacylglycerol = CMP + a phosphatidylethanolamine.	tmpzr1t_l9r_go_relaxed.owl	CDP-ethanolamine:1,2-diacylglycerol ethanolaminephosphotransferase activity|diacylglycerol ethanolaminephosphotransferase activity|phosphorylethanolamine-glyceride transferase activity|EPT|CDPethanolamine diglyceride phosphotransferase activity				MetaCyc:ETHANOLAMINEPHOSPHOTRANSFERASE-RXN|RHEA:32943|Reactome:R-HSA-1482962|EC:2.7.8.1									molecular_function											owl:Class	
GO:0008758	biolink:NamedThing	UDP-2,3-diacylglucosamine hydrolase activity	Catalysis of the reaction: H2O + UDP-2,3-bis(3-hydroxymyristoyl)glucosamine = 2,3-bis(3-hydroxymyristoyl)-beta-D-glucosaminyl 1-phosphate + UMP.	tmpzr1t_l9r_go_relaxed.owl					RHEA:25213|MetaCyc:LIPIDXSYNTHESIS-RXN									molecular_function											owl:Class	
GO:0008853	biolink:NamedThing	exodeoxyribonuclease III activity	Catalysis of the degradation of double-stranded DNA. It acts progressively in a 3' to 5' direction, releasing 5'-phosphomononucleotides.	tmpzr1t_l9r_go_relaxed.owl	Escherichia coli exonuclease III|E. coli exonuclease III|exonuclease III activity|E. coli exonuclease III activity|endoribonuclease III				MetaCyc:3.1.11.2-RXN|EC:3.1.11.2									molecular_function											owl:Class	
GO:0045870	biolink:NamedThing	positive regulation of single stranded viral RNA replication via double stranded DNA intermediate	Any process that activates or increases the frequency, rate or extent of retroviral genome replication.	tmpzr1t_l9r_go_relaxed.owl	upregulation of retroviral genome replication|stimulation of retroviral genome replication|up regulation of retroviral genome replication|activation of retroviral genome replication|up-regulation of retroviral genome replication|positive regulation of retroviral genome replication													biological_process											owl:Class	
GO:0102258	biolink:NamedThing	1,3-diacylglycerol acylhydrolase activity	Catalysis of the reaction: H2O + a 1,3-diglyceride = a monoglyceride + a fatty acid.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-12433									molecular_function											owl:Class	
GO:1900285	biolink:NamedThing	regulation of cellotriose transport	Any process that modulates the frequency, rate or extent of cellotriose transport.	tmpzr1t_l9r_go_relaxed.owl								tt	2012-04-05T05:56:46Z					biological_process											owl:Class	
GO:0061970	biolink:NamedThing	maintenance of right sidedness	The organization process that preserves the right sidedness in an organism's body plan or part of an organism with respect to the left and right halves.	tmpzr1t_l9r_go_relaxed.owl								dph	2018-02-12T16:45:33Z					biological_process											owl:Class	
GO:0030352	biolink:NamedThing	inositol-1,4,5,6-tetrakisphosphate 6-phosphatase activity	Catalysis of the reaction: inositol-1,4,5,6-tetrakisphosphate + H2O = inositol-1,4,5-trisphosphate + phosphate.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0071117	biolink:NamedThing	alpha5-beta1 integrin-fibronectin-NOV complex	A protein complex that consists of an alpha5-beta1 integrin complex bound to fibronectin and the extracellular matrix protein NOV.	tmpzr1t_l9r_go_relaxed.owl	ITGA5-ITGB1-FN-1-NOV complex							mah	2009-11-13T02:19:52Z					cellular_component											owl:Class	
GO:0000401	biolink:NamedThing	open form four-way junction DNA binding	Binding to a DNA segment containing the open form of a four-way junction, also known as a Holliday junction, a structure where two DNA double strands are held together by reciprocal exchange of two of the four strands, one strand each from the two original helices. The open form of a four-way junction can be diagrammed without any of the strands crossing over.	tmpzr1t_l9r_go_relaxed.owl	open form Holliday junction binding													molecular_function											owl:Class	
GO:0102844	biolink:NamedThing	1-18:2-2-16:1-monogalactosyldiacylglycerol desaturase activity (SN2-16:2 forming)	Catalysis of the reaction: 1-18:2-2-16:1-monogalactosyldiacylglycerol + O2 + a reduced electron acceptor = 1-18:2-2-16:2-monogalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-8305|EC:1.14.19.23									molecular_function											owl:Class	
GO:0047554	biolink:NamedThing	2-pyrone-4,6-dicarboxylate lactonase activity	Catalysis of the reaction: 2-oxo-2H-pyran-4,6-dicarboxylate + H(2)O = 4-carboxy-2-hydroxyhexa-2,4-dienedioate + H(+).	tmpzr1t_l9r_go_relaxed.owl	2-pyrone-4,6-dicarboxylate lactonohydrolase activity				KEGG_REACTION:R04277|RHEA:10644|EC:3.1.1.57|MetaCyc:RXN-2462									molecular_function											owl:Class	
GO:0102671	biolink:NamedThing	6a-hydroxymaackiain-3-O-methyltransferase activity	Catalysis of the reaction: (+)-6a-hydroxymaackiain + S-adenosyl-L-methionine  <=> H+ + (+)-pisatin + S-adenosyl-L-homocysteine.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-4002|RHEA:35471|EC:2.1.1.270									molecular_function											owl:Class	
GO:0050088	biolink:NamedThing	mannose-6-phosphate 6-reductase activity	Catalysis of the reaction: D-mannitol 1-phosphate + NADP(+) = D-mannose 6-phosphate + 3 H(+) + NADPH.	tmpzr1t_l9r_go_relaxed.owl	D-mannitol-1-phosphate:NADP+ 6-oxidoreductase activity|6-phosphomannose reductase activity|NADPH-dependent mannose 6-phosphate reductase activity|NADP-dependent mannose-6-P:mannitol-1-P oxidoreductase activity|NADPH-dependent M6P reductase activity|NADPH-mannose-6-P reductase activity|mannose-6-phosphate reductase activity				MetaCyc:MANNOSE-6-PHOSPHATE-6-REDUCTASE-RXN|RHEA:14925|EC:1.1.1.224|KEGG_REACTION:R01817									molecular_function											owl:Class	
GO:0034007	biolink:NamedThing	S-linalool synthase activity	Catalysis of the reaction: geranyl diphosphate + H(2)O = (S)-linalool + diphosphate.	tmpzr1t_l9r_go_relaxed.owl	3S-linalool synthase activity|LIS|geranyl-diphosphate diphosphate-lyase [(3S)-linalool-forming] activity				MetaCyc:4.2.3.25-RXN|EC:4.2.3.25|RHEA:24116|KEGG_REACTION:R07631									molecular_function											owl:Class	
GO:1905519	biolink:NamedThing	negative regulation of presynaptic active zone assembly	Any process that stops, prevents or reduces the frequency, rate or extent of presynaptic active zone assembly.	tmpzr1t_l9r_go_relaxed.owl	down regulation of pre-synaptic active zone formation|down regulation of presynaptic active zone assembly|negative regulation of presynaptic active zone formation|negative regulation of pre-synaptic active zone assembly|down regulation of pre-synaptic active zone assembly|downregulation of pre-synaptic active zone component formation|inhibition of pre-synaptic active zone formation|down-regulation of presynaptic active zone assembly|downregulation of presynaptic active zone assembly|downregulation of presynaptic active zone formation|negative regulation of pre-synaptic active zone component assembly|down-regulation of pre-synaptic active zone component assembly|inhibition of pre-synaptic active zone assembly|downregulation of pre-synaptic active zone assembly|inhibition of presynaptic active zone assembly|down regulation of presynaptic active zone formation|downregulation of pre-synaptic active zone component assembly|down regulation of pre-synaptic active zone component formation|down-regulation of pre-synaptic active zone formation|down-regulation of presynaptic active zone formation|inhibition of pre-synaptic active zone component assembly|inhibition of presynaptic active zone formation|negative regulation of pre-synaptic active zone component formation|downregulation of pre-synaptic active zone formation|down-regulation of pre-synaptic active zone assembly|down regulation of pre-synaptic active zone component assembly|inhibition of pre-synaptic active zone component formation|down-regulation of pre-synaptic active zone component formation|negative regulation of pre-synaptic active zone formation							rl	2016-10-01T09:38:00Z					biological_process											owl:Class	
GO:0036381	biolink:NamedThing	pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity	Catalysis of the reaction: D-ribose 5-phosphate + D-glyceraldehyde 3-phosphate + L-glutamine = pyridoxal 5'-phosphate + L-glutamate + 3 H2O + phosphate. The reaction occurs in two steps: L-glutamine + H2O = L-glutamate + NH3, and subsequently D-ribose 5-phosphate + D-glyceraldehyde 3-phosphate + NH3 = pyridoxal 5'-phosphate + 4 H2O + phosphate.	tmpzr1t_l9r_go_relaxed.owl	pyridoxal 5'-phosphate synthase (glutamine hydrolyzing) activity|PdxST activity				EC:4.3.3.6|RHEA:31507|MetaCyc:RXN-11322|KEGG_REACTION:R10089			bf	2013-05-23T11:15:37Z					molecular_function											owl:Class	
GO:0021568	biolink:NamedThing	rhombomere 2 development	The process whose specific outcome is the progression of rhombomere 2 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0047156	biolink:NamedThing	acetoin-ribose-5-phosphate transaldolase activity	Catalysis of the reaction: D-ribose 5-phosphate + acetoin = 1-deoxy-D-altro-heptulose 7-phosphate + acetaldehyde.	tmpzr1t_l9r_go_relaxed.owl	1-deoxy-D-altro-heptulose-7-phosphate synthetase activity|3-hydroxybutan-3-one:D-ribose-5-phosphate aldehydetransferase activity|1-deoxy-D-altro-heptulose-7-phosphate synthase activity|3-hydroxybutan-2-one:D-ribose-5-phosphate aldehydetransferase activity				RHEA:21504|MetaCyc:2.2.1.4-RXN|KEGG_REACTION:R02345|EC:2.2.1.4									molecular_function											owl:Class	
GO:0004382	biolink:NamedThing	guanosine-diphosphatase activity	Catalysis of the reaction: GDP + H2O = GMP + phosphate.	tmpzr1t_l9r_go_relaxed.owl	guanosine diphosphatase activity|GDP phosphohydrolase activity|guanosine 5'-diphosphatase activity|GDPase activity				RHEA:22156|EC:3.6.1.42|MetaCyc:GUANOSINE-DIPHOSPHATASE-RXN									molecular_function											owl:Class	
GO:0044685	biolink:NamedThing	tetrahydromethanopterin-dependent serine hydroxymethyltransferase activity	Catalysis of the reaction: tetrahydromethanopterin + L-serine = 5,10-methylenetetrahydromethanopterin + glycine + H2O.	tmpzr1t_l9r_go_relaxed.owl					EC:2.1.2.-			jl	2012-08-15T14:13:07Z					molecular_function											owl:Class	
GO:1904789	biolink:NamedThing	regulation of mitotic actomyosin contractile ring maintenance	Any process that modulates the frequency, rate or extent of mitotic actomyosin contractile ring maintenance.	tmpzr1t_l9r_go_relaxed.owl	regulation of contractile ring maintenance involved in cell cycle cytokinesis involved in mitotic cell cycle|regulation of cytokinesis, contractile ring maintenance, involved in cytokinesis during cell cycle involved in mitotic cell cycle							mah	2015-11-06T15:42:49Z					biological_process											owl:Class	
GO:0102517	biolink:NamedThing	oleate 12-hydroxylase activity	Catalysis of the reaction: oleoyl-CoA + NADH + O2 + H+ = ricinoleyl-CoA + NAD + H2O.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-14487									molecular_function											owl:Class	
GO:0047795	biolink:NamedThing	cyclohexane-1,2-diol dehydrogenase activity	Catalysis of the reaction: trans-cyclohexane-1,2-diol + NAD+ = 2-hydroxycyclohexan-1-one + NADH.	tmpzr1t_l9r_go_relaxed.owl	trans-cyclohexane-1,2-diol:NAD+ 1-oxidoreductase activity				RHEA:18141|MetaCyc:CYCLOHEXANE-12-DIOL-DEHYDROGENASE-RXN|EC:1.1.1.174									molecular_function											owl:Class	
GO:0031486	biolink:NamedThing	myosin XVI complex	A myosin complex containing a class XVI myosin heavy chains and associated light chains; myosin XVI heavy chains contain ankyrin repeat.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0035654	biolink:NamedThing	clathrin-coated vesicle cargo loading, AP-3-mediated	Formation of a macromolecular complex between proteins of the AP-3 adaptor complex and proteins and/or lipoproteins that are going to be transported by a clathrin-coated vesicle. In some cases, the AP-3 complex is a heterotetrameric AP-type membrane coat adaptor complex that, in some organisms, links clathrin to the membrane surface of a vesicle.	tmpzr1t_l9r_go_relaxed.owl	cargo loading into clathrin-coated vesicle, AP-3-mediated							bf	2011-01-25T11:02:30Z					biological_process											owl:Class	
GO:0030322	biolink:NamedThing	stabilization of membrane potential	The accomplishment of a non-fluctuating membrane potential, the electric potential existing across any membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0048458	biolink:NamedThing	floral whorl formation	The process that gives rise to the floral whorl. This process pertains to the initial formation of a structure from unspecified parts.	tmpzr1t_l9r_go_relaxed.owl												GO:0048415		biological_process											owl:Class	
GO:0005118	biolink:NamedThing	sevenless binding	Binding to a sevenless (sev) protein, a receptor tyrosine kinase.	tmpzr1t_l9r_go_relaxed.owl	sev ligand|sev binding|sevenless ligand													molecular_function											owl:Class	
GO:0033857	biolink:NamedThing	diphosphoinositol-pentakisphosphate kinase activity	Catalysis of the reaction: ATP + 1D-myo-inositol 5-diphosphate pentakisphosphate = ADP + 1D-myo-inositol bisdiphosphate tetrakisphosphate.	tmpzr1t_l9r_go_relaxed.owl	PPIP5K|ATP:5-diphospho-1D-myo-inositol-pentakisphosphate phosphotransferase activity|PP-InsP5 kinase activity|PPIP5K2|PP-IP5 kinase activity|PPIP5K1|VIP2|VIP1				EC:2.7.4.24									molecular_function											owl:Class	
GO:1904515	biolink:NamedThing	positive regulation of TORC2 signaling	Any process that activates or increases the frequency, rate or extent of TORC2 signaling.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of TORC2 signaling|upregulation of TORC2 signaling|activation of TORC2 signal transduction|up-regulation of TORC2 signal transduction|upregulation of TORC2 signal transduction|up regulation of TORC2 signal transduction|up regulation of TORC2 signaling|activation of TORC2 signaling|positive regulation of TORC2 signal transduction							al	2015-07-28T16:09:55Z					biological_process											owl:Class	
GO:0071141	biolink:NamedThing	SMAD protein complex	A protein complex that consists of only SMAD proteins; may be homomeric or heteromeric. Heteromeric complexes act as transcription factors while homomeric complexes exist but are transcriptionally inactive. Hetero- versus homotrimerization is largely enthalpy driven.	tmpzr1t_l9r_go_relaxed.owl	SMAD complex							mah	2009-11-16T02:28:59Z					cellular_component											owl:Class	
GO:0043759	biolink:NamedThing	methylbutanoate-CoA ligase activity	Catalysis of the reaction: ATP + 2-methylbutanoate + CoA = AMP +  diphosphate + 2-methylbutanoyl-CoA.	tmpzr1t_l9r_go_relaxed.owl	branched chain acyl CoA synthetase (ADP-forming) activity|branched-chain acyl CoA synthetase (ADP-forming) activity|branched chain acyl-CoA synthetase (ADP-forming) activity|branched-chain acyl-CoA synthetase (ADP-forming) activity	https://github.com/geneontology/go-ontology/issues/18967			RHEA:46180									molecular_function											owl:Class	
GO:0099608	biolink:NamedThing	regulation of action potential firing pattern	Any process that regulates the temporal pattern of a sequence of action potentials in a neuron.	tmpzr1t_l9r_go_relaxed.owl	spike train sculpting													biological_process											owl:Class	
GO:0051800	biolink:NamedThing	phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity	Catalysis of the reaction: phosphatidylinositol-3,4-bisphosphate + H2O = phosphatidylinositol-4-phosphate + phosphate.	tmpzr1t_l9r_go_relaxed.owl	PTEN activity				Reactome:R-HSA-1676149|Reactome:R-HSA-1676204									molecular_function											owl:Class	
GO:0102907	biolink:NamedThing	sesquisabinene synthase activity	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate(3-) <=> diphosphoric acid + sesquisabinene.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-8622									molecular_function											owl:Class	
GO:0004137	biolink:NamedThing	deoxycytidine kinase activity	Catalysis of the reaction: NTP + deoxycytidine = NDP + CMP.	tmpzr1t_l9r_go_relaxed.owl	arabinofuranosylcytosine kinase activity|Ara-C kinase activity|NTP:deoxycytidine 5'-phosphotransferase activity|deoxycytidine-cytidine kinase activity|2'-deoxycytidine kinase activity|deoxycytidine kinase (phosphorylating)				RHEA:20061|EC:2.7.1.74|MetaCyc:DEOXYCYTIDINE-KINASE-RXN									molecular_function											owl:Class	
GO:0042632	biolink:NamedThing	cholesterol homeostasis	Any process involved in the maintenance of an internal steady state of cholesterol within an organism or cell.	tmpzr1t_l9r_go_relaxed.owl	regulation of cholesterol homeostasis|positive regulation of cholesterol homeostasis											GO:2000188|GO:2000189		biological_process											owl:Class	
GO:0055092	biolink:NamedThing	sterol homeostasis	Any process involved in the maintenance of an internal steady state of sterol within an organism or cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0102770	biolink:NamedThing	inositol phosphorylceramide synthase activity	Catalysis of the reaction: an L-1-phosphatidyl-inositol + a dihydroceramide = an inositol phosphodihydroceramide + a 1,2-diacyl-sn-glycerol.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-7795									molecular_function											owl:Class	
GO:0015817	biolink:NamedThing	histidine transport	The directed movement of histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	L-histidine transport													biological_process											owl:Class	
GO:0036336	biolink:NamedThing	dendritic cell migration	The movement of a dendritic cell within or between different tissues and organs of the body.	tmpzr1t_l9r_go_relaxed.owl								bf	2012-09-05T10:24:46Z					biological_process											owl:Class	
GO:0034013	biolink:NamedThing	aliphatic aldoxime dehydratase activity	Catalysis of the reaction: an aliphatic aldoxime = an aliphatic nitrile + H2O.	tmpzr1t_l9r_go_relaxed.owl	aliphatic aldoxime hydro-lyase activity|OxdA|aliphatic aldoxime hydro-lyase (aliphatic-nitrile-forming) activity				EC:4.99.1.5|RHEA:11316|MetaCyc:4.99.1.5-RXN									molecular_function											owl:Class	
GO:0032359	biolink:NamedThing	provirus excision	The molecular events that lead to the excision of a viral genome from the host genome.	tmpzr1t_l9r_go_relaxed.owl	prophage excision													biological_process											owl:Class	
GO:0014886	biolink:NamedThing	transition between slow and fast fiber	The process of conversion of slow-contracting muscle fibers to a faster character. This may involve increasing of contractile rate, fast myosin gene induction, increase in glycolytic metabolic properties, altered electrophysiology and altered innervation. This process also regulates skeletal muscle adapatation.	tmpzr1t_l9r_go_relaxed.owl	transition between slow and fast fibre|transition slow-fast fiber|transition slow-fast fibre													biological_process											owl:Class	
GO:0090632	biolink:NamedThing	N-glycolylneuraminic acid (Neu5Gc) cytidylyltransferase activity	Catalysis of the reaction: CTP + Neu5Gc = diphosphate + CMP-Neu5Gc.	tmpzr1t_l9r_go_relaxed.owl	CMP-Neu5Gc synthetase activity							tb	2015-03-19T15:05:54Z					molecular_function											owl:Class	
GO:0052092	biolink:NamedThing	positive regulation of nutrient release by host	Any process in which an organism activates, maintains or increases the frequency, rate or extent of the release of nutrients from its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	up-regulation by symbiont of nutrient release from host|stimulation by symbiont of nutrient release from host|upregulation by symbiont of nutrient release from host|positive regulation by symbiont of nutrient release from host|up regulation by symbiont of nutrient release from host|promotion of nutrient release from host|activation by symbiont of nutrient release from host													biological_process											owl:Class	
GO:0052091	biolink:NamedThing	modulation of nutrient release by host	Any process in which an organism modulates the frequency, rate or extent of the release of nutrients from its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	modulation by symbiont of nutrient release from host													biological_process											owl:Class	
GO:0051116	biolink:NamedThing	cobaltochelatase activity	Catalysis of the reaction: ATP + Co(2+) + H(2)O + hydrogenobyrinate a,c-diamide = ADP + cob(II)yrinate a,c diamide + 4 H(+) + phosphate.	tmpzr1t_l9r_go_relaxed.owl	hydrogenobyrinic-acid-a,c-diamide:cobalt cobalt-ligase (ADP-forming)|CobNST|hydrogenobyrinic acid a,c-diamide cobaltochelatase activity|CobN-CobST				RHEA:15341|KEGG_REACTION:R05227|EC:6.6.1.2|MetaCyc:R342-RXN									molecular_function											owl:Class	
GO:0048027	biolink:NamedThing	mRNA 5'-UTR binding	Binding to an mRNA molecule at its 5' untranslated region.	tmpzr1t_l9r_go_relaxed.owl	mRNA 5' UTR binding													molecular_function											owl:Class	
GO:0019186	biolink:NamedThing	acyl-CoA N-acyltransferase activity	Catalysis of the transfer of an acyl group from acyl-CoA to a nitrogen atom on an acceptor molecule.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0030056	biolink:NamedThing	hemidesmosome	A cell-substrate junction (attachment structure) found in epithelial cells that links intermediate filaments to extracellular matrices via transmembrane complexes. In vertebrates, hemidesmosomes mediate contact between the basal side of epithelial cells and the basal lamina. In C. elegans, hemidesmosomes connect epithelial cells to distinct extracellular matrices on both the apical and basal cell surfaces.	tmpzr1t_l9r_go_relaxed.owl	trans-epithelial attachment|epidermal attachment structure|fibrous organelle|hemi-adherens junction				Wikipedia:Hemidesmosome									cellular_component											owl:Class	
GO:0000994	biolink:NamedThing	RNA polymerase III core binding	Binding to an RNA polymerase III core enzyme, a multisubunit eukaryotic nuclear RNA polymerase typically composed of seventeen subunits.	tmpzr1t_l9r_go_relaxed.owl								krc	2010-08-11T03:58:58Z					molecular_function											owl:Class	
GO:0002348	biolink:NamedThing	central B cell positive selection	Any process leading to positive selection of B cells in the bone marrow. Positive selection is the process in which B or T cells are selected to survive based on signaling through their antigen receptors.	tmpzr1t_l9r_go_relaxed.owl	central B-cell positive selection|central B lymphocyte positive selection|central B-lymphocyte positive selection													biological_process											owl:Class	
GO:0018743	biolink:NamedThing	phenanthrene-9,10-epoxide hydrolase (9R,10R-forming) activity	Catalysis of the reaction: phenanthrene-9,10-oxide + H2O = trans-9R,10R-dihydrodiolphenanthrene.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0560|EC:3.3.2.-									molecular_function											owl:Class	
GO:0140092	biolink:NamedThing	bBAF complex	A brain-specific SWI/SNF-type complex that contains eight or nine proteins, including both conserved (core) and nonconserved components; contains the ATPase product of either the SMARCA4/BAF190A/BRG1 gene, the mammalian ortholog of the yeast SNF2 gene, or the SMARCA2/BAF190B/BRM gene, the mammalian ortholog of the Drosophila brm (brahma) gene, or an ortholog of either of these genes. Compared to the neuron-specific nBAF complex (GO:0071565) it does not contain DPF1, DPF3 or SMARCC1 or their orthologs. May contain PB1/BAF180.	tmpzr1t_l9r_go_relaxed.owl	brain-specific BAF complex|brain-specific SWI/SNF complex							pg	2017-09-05T09:22:41Z					cellular_component											owl:Class	
GO:0044720	biolink:NamedThing	negative regulation of imaginal disc-derived wing size	Any process that reduces the size of an imaginal disc-derived wing.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-10-18T13:50:49Z					biological_process											owl:Class	
GO:0047135	biolink:NamedThing	bis-gamma-glutamylcystine reductase activity	Catalysis of the reaction: 2 L-gamma-glutamyl-L-cysteine + NADP(+) = bis-gamma-glutamylcystine + H(+) + NADPH.	tmpzr1t_l9r_go_relaxed.owl	Bis-gamma-glutamylcystine reductase (NADPH)|bis-gamma-glutamylcystine reductase (NADPH) activity|gamma-glutamylcysteine:NADP+ oxidoreductase activity|NADPH2:bis-gamma-glutamylcysteine oxidoreductase activity|NADPH:bis-gamma-glutamylcysteine oxidoreductase activity|bis-g-glutamylcystine reductase (NADPH) activity				KEGG_REACTION:R02742|RHEA:11980|MetaCyc:1.6.4.9-RXN|EC:1.8.1.13									molecular_function											owl:Class	
GO:0010217	biolink:NamedThing	cellular aluminum ion homeostasis	Any process involved in the maintenance of an internal steady state of aluminum ions at the level of a cell.	tmpzr1t_l9r_go_relaxed.owl	cellular aluminium ion homeostasis													biological_process											owl:Class	
GO:0008908	biolink:NamedThing	isochorismatase activity	Catalysis of the reaction: H(2)O + isochorismate = 2,3-dihydroxy-2,3-dihydrobenzoate + pyruvate.	tmpzr1t_l9r_go_relaxed.owl	2,3-dihydro-2,3-dihydroxybenzoate synthase activity|2,3 dihydro-2,3 dihydroxybenzoate synthase activity|2,3-dihydroxy-2,3-dihydrobenzoic synthase activity|2,3-dihydroxy-2,3-dihydrobenzoate synthase activity|isochorismate pyruvate-hydrolase activity				RHEA:11112|KEGG_REACTION:R03037|EC:3.3.2.1|MetaCyc:ISOCHORMAT-RXN									molecular_function											owl:Class	
GO:0030058	biolink:NamedThing	amine dehydrogenase activity	Catalysis of the reaction: an aliphatic amine + an acceptor (A) + H2O = an aldehyde + a reduced acceptor (AH2) + NH4+.	tmpzr1t_l9r_go_relaxed.owl	MADH activity|primary-amine dehydrogenase activity|methylamine dehydrogenase activity|primary-amine:acceptor oxidoreductase (deaminating)|amine: (acceptor) oxidoreductase (deaminating)	https://github.com/geneontology/go-ontology/issues/21650			RHEA:51128|UM-BBD_enzymeID:e0058									molecular_function											owl:Class	
GO:0051562	biolink:NamedThing	negative regulation of mitochondrial calcium ion concentration	Any process that decreases the concentration of calcium ions in mitochondria.	tmpzr1t_l9r_go_relaxed.owl	mitochondrial calcium ion concentration reduction|reduction of calcium ion concentration in mitochondria|reduction of calcium ion concentration in mitochondrion|reduction of mitochondrial calcium ion concentration													biological_process											owl:Class	
GO:0002352	biolink:NamedThing	B cell negative selection	Any process leading to negative selection in B cells. Mechanisms of negative selection include anergy and deletion.	tmpzr1t_l9r_go_relaxed.owl	B-lymphocyte negative selection|B lymphocyte negative selection|B-cell negative selection													biological_process											owl:Class	
GO:0050121	biolink:NamedThing	N-acylglucosamine 2-epimerase activity	Catalysis of the reaction: N-acyl-D-glucosamine = N-acyl-D-mannosamine.	tmpzr1t_l9r_go_relaxed.owl	N-acetylglucosamine 2-epimerase activity|GlcNAc 2-epimerase activity|N-acetyl-D-glucosamine 2-epimerase activity|N-acyl-D-glucosamine 2-epimerase activity|acylglucosamine 2-epimerase activity				RHEA:19033|EC:5.1.3.8|Reactome:R-HSA-6803761|MetaCyc:N-ACYLGLUCOSAMINE-2-EPIMERASE-RXN									molecular_function											owl:Class	
GO:0047657	biolink:NamedThing	alpha-1,3-glucan synthase activity	Catalysis of the reaction: UDP-glucose + [alpha-D-glucosyl-(1,3)]n = UDP + [alpha-D-glucosyl-(1,3)]n+1.	tmpzr1t_l9r_go_relaxed.owl	UDP-glucose:alpha-D-(1->3)-glucan 3-alpha-D-glucosyltransferase activity|uridine diphosphoglucose-1,3-alpha-glucan glucosyltransferase activity|1,3-alpha-D-glucan synthase activity|a-1,3-glucan synthase activity|1,3-alpha-glucan synthase activity|UDPglucose:alpha-D-(1->3)-glucan 3-alpha-D-glucosyltransferase activity				MetaCyc:ALPHA-13-GLUCAN-SYNTHASE-RXN|RHEA:19749|EC:2.4.1.183									molecular_function											owl:Class	
GO:1905543	biolink:NamedThing	interleukin-15 receptor complex	A protein complex that binds interleukin-15 (IL-15) and that consists of, at a minimum, an interleukin, an alpha, beta and gamma chain as well as optional additional kinase subunits. The alpha chain is unique to binds IL-15 while it shares the beta chain with the IL-2 receptor and the cytokine receptor common gamma chain with multiple interleukin receptors.	tmpzr1t_l9r_go_relaxed.owl	interleukin-15-receptor complex|IL15-receptor complex|IL-15 receptor complex|IL-15-receptor complex|IL15 receptor complex					An example of this is IL15RA in human (Q13261) in PMID:23104097 (inferred from physical interaction).		bhm	2016-10-10T13:38:12Z					cellular_component											owl:Class	
GO:0097600	biolink:NamedThing	exoxylanase activity	A xylanase activity that acts on one of the ends of a xylan polymer which does not contain side chains.	tmpzr1t_l9r_go_relaxed.owl								pr	2014-05-06T13:48:27Z					molecular_function											owl:Class	
GO:0052826	biolink:NamedThing	inositol hexakisphosphate 2-phosphatase activity	Catalysis of the reaction: myo-inositol hexakisphosphate + H2O = myo-inositol 1,3,4,5,6-pentakisphosphate + phosphate.	tmpzr1t_l9r_go_relaxed.owl	1D-myo-inositol-hexakisphosphate 2-phosphohydrolase activity				Reactome:R-HSA-1855225|EC:3.1.3.62			ai	2011-11-29T09:52:14Z					molecular_function											owl:Class	
GO:0008824	biolink:NamedThing	cyanate hydratase activity	Catalysis of the reaction: cyanate + H2O = carbamate.	tmpzr1t_l9r_go_relaxed.owl	cyanate C-N-lyase activity|carbamate hydro-lyase activity|cyanate hydrolase activity|cyanase activity|cyanate aminohydrolase activity|cyanate lyase activity				MetaCyc:R524-RXN|RHEA:11120|UM-BBD_reactionID:r0608|EC:4.2.1.104	Note that this function was formerly EC:4.3.99.1.								molecular_function											owl:Class	
GO:0010406	biolink:NamedThing	classical arabinogalactan protein metabolic process	The chemical reactions and pathways involving a cell wall arabinogalactan II glycoprotein, which is composed of a group of core protein containing Hyp, Ala, Ser, Thr and Gly as the major amino acid constituents, and the C-terminus is GPI anchored.	tmpzr1t_l9r_go_relaxed.owl	classical-arabinogalactan protein metabolism													biological_process											owl:Class	
GO:0007089	biolink:NamedThing	traversing start control point of mitotic cell cycle	A cell cycle process by which a cell commits to entering S phase via a positive feedback mechanism between the regulation of transcription and G1 CDK activity.	tmpzr1t_l9r_go_relaxed.owl												GO:0000081		biological_process											owl:Class	
GO:0044258	biolink:NamedThing	intestinal lipid catabolic process	The chemical reactions and pathways resulting in the breakdown into fatty acids and monoglycerides of lipids in the small intestine. Lipids are broken down by lipases released by the pancreas.	tmpzr1t_l9r_go_relaxed.owl	intestinal lipid breakdown|intestinal lipid catabolism|intestinal lipid degradation													biological_process											owl:Class	
GO:0106357	biolink:NamedThing	glycerol-1-phosphate dehydrogenase [NAD+] activity	Catalysis of the reaction: NAD+ + sn-glycerol 1-phosphate = dihydroxyacetone phosphate + H+ + NADH.	tmpzr1t_l9r_go_relaxed.owl					RHEA:21412			hjd	2021-02-02T06:07:55Z					molecular_function											owl:Class	
GO:0097522	biolink:NamedThing	protein-DNA ISRE complex	A protein-DNA complex formed through interaction of the protein(s) with an interferon-stimulated response element (ISRE) in the DNA.	tmpzr1t_l9r_go_relaxed.owl								pr	2013-10-17T14:35:07Z					cellular_component											owl:Class	
GO:0052787	biolink:NamedThing	alpha-linked polysaccharide catabolism to maltopentaose	The breakdown of large alpha-linked polysaccharides by hydrolysis of (1->4)-alpha-D-glucosidic linkages to yield maltopentaose.	tmpzr1t_l9r_go_relaxed.owl	alpha-amylase-mediated polysaccharide catabolism, producing maltopentaose|maltopentaose-forming alpha-amylase activity							ai	2011-10-04T10:06:44Z					biological_process											owl:Class	
GO:0034957	biolink:NamedThing	3-nitrophenol nitroreductase activity	Catalysis of the reaction: 3-nitrophenol + 2 NADH + 2 H+ = 3-hydroxyaminophenol + 2 NAD+ + H2O.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r1495									molecular_function											owl:Class	
GO:0047681	biolink:NamedThing	aryl-alcohol dehydrogenase (NADP+) activity	Catalysis of the reaction: an aromatic alcohol + NADP+ = an aromatic aldehyde + NADPH.	tmpzr1t_l9r_go_relaxed.owl	NADPH-linked benzaldehyde reductase activity|aryl-alcohol:NADP+ oxidoreductase activity|aryl alcohol dehydrogenase (nicotinamide adenine dinucleotide phosphate)				MetaCyc:ARYL-ALCOHOL-DEHYDROGENASE-NADP+-RXN|EC:1.1.1.91|RHEA:17761									molecular_function											owl:Class	
GO:0045296	biolink:NamedThing	cadherin binding	Binding to cadherin, a type I membrane protein involved in cell adhesion.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0018935	biolink:NamedThing	aerobic nitrilotriacetate metabolic process	The chemical reactions and pathways involving nitrilotriacetate, the aminotricarboxylic acid N(CH2COO-)3, that occur in the presence of oxygen.	tmpzr1t_l9r_go_relaxed.owl	aerobic nitrilotriacetate metabolism													biological_process											owl:Class	
GO:0005598	biolink:NamedThing	short-chain collagen trimer	Any collagen trimer that does not form fibrils and that is relatively short compared to the collagen trimers that do form fibrils.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0050417	biolink:NamedThing	glutamin-(asparagin-)ase activity	Catalysis of the reaction: H2O + L-glutamine = NH3 + L-glutamate; and H2O + L-asparagine = NH3 + L-aspartate.	tmpzr1t_l9r_go_relaxed.owl	L-ASNase/L-GLNase activity|glutaminase-asparaginase activity|glutaminase-(asparagin-)ase activity|L-asparagine/L-glutamine amidohydrolase activity|L-glutamine(L-asparagine) amidohydrolase activity				MetaCyc:GLUTAMINASE-ASPARAGIN-ASE-RXN|EC:3.5.1.38									molecular_function											owl:Class	
GO:0103030	biolink:NamedThing	ethylglyoxal reductase (NADH-dependent, hydroxyacetone-forming) activity	Catalysis of the reaction: H+ + methylglyoxal + NADH = hydroxyacetone + NAD.	tmpzr1t_l9r_go_relaxed.owl					RHEA:35615|MetaCyc:RXN0-5213									molecular_function											owl:Class	
GO:1904368	biolink:NamedThing	regulation of sclerenchyma cell differentiation	Any process that modulates the frequency, rate or extent of sclerenchyma cell differentiation.	tmpzr1t_l9r_go_relaxed.owl								tb	2015-06-17T19:53:00Z					biological_process											owl:Class	
GO:0050148	biolink:NamedThing	nucleotide diphosphokinase activity	Catalysis of the reaction: ATP + nucleoside 5'-phosphate = AMP + 5'-phosphonucleoside 3'-diphosphate.	tmpzr1t_l9r_go_relaxed.owl	nucleotide pyrophosphokinase activity|ATP nucleotide 3'-pyrophosphokinase activity|nucleotide 3'-pyrophosphokinase activity|ATP:nucleotide pyrophosphotransferase activity|ATP:nucleoside-5'-phosphate diphosphotransferase activity				RHEA:12713|EC:2.7.6.4|MetaCyc:NUCLEOTIDE-PYROPHOSPHOKINASE-RXN									molecular_function											owl:Class	
GO:1902489	biolink:NamedThing	hepatoblast apoptotic process	Any apoptotic process in a hepatoblast.	tmpzr1t_l9r_go_relaxed.owl	hepatoblast apoptosis							cls	2013-11-12T17:02:52Z					biological_process											owl:Class	
GO:0120216	biolink:NamedThing	matrilin complex	A cartilage extracellular matrix complex that mediates interactions between major components of the extracellular matrix such as collagens and proteoglycans and contributes to their fibrillar network. Exists as an obligate homotrimer.	tmpzr1t_l9r_go_relaxed.owl	matrilin family complex|matrilin-3 complex|matrilin-2 complex|matrilin-1 complex|matrilin-4 complex							krc	2019-07-09T22:05:11Z					cellular_component											owl:Class	
GO:0097388	biolink:NamedThing	chemokine (C-C motif) ligand 19 production	The appearance of chemokine (C-C motif) ligand 19 (CCL19) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	tmpzr1t_l9r_go_relaxed.owl	macrophage inflammatory protein-3-beta production|CCL19 production|MIP-3-beta production|EBI1 ligand chemokine production|ELC production							pr	2012-10-23T07:54:10Z					biological_process											owl:Class	
GO:0050338	biolink:NamedThing	thiosulfate dehydrogenase activity	Catalysis of the reaction: 2 thiosulfate + 2 ferricytochrome c = tetrathionate + 2 ferrocytochrome c.	tmpzr1t_l9r_go_relaxed.owl	thiosulfate-acceptor oxidoreductase activity|tetrathionate synthase activity|thiosulphate dehydrogenase activity|thiosulfate-oxidizing enzyme|thiosulfate:ferricytochrome-c oxidoreductase activity|thiosulfate oxidase activity				RHEA:20549|EC:1.8.2.2|MetaCyc:THIOSULFATE-DEHYDROGENASE-RXN									molecular_function											owl:Class	
GO:0090591	biolink:NamedThing	protein-N(PI)-phosphohistidine-N-acetyl-mannosamine phosphotransferase system transporter activity	Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + N-acetyl-mannosamine(out) = protein histidine +N-acetyl- mannosamine-6-phosphate(in).	tmpzr1t_l9r_go_relaxed.owl								tb	2014-06-04T16:33:01Z					molecular_function											owl:Class	
GO:0102298	biolink:NamedThing	selenocystathione synthase activity	Catalysis of the reaction: L-selenocysteine  + O-phosphonato-L-homoserine = hydrogenphosphate + L-selenocystathionine.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-12728									molecular_function											owl:Class	
GO:0036058	biolink:NamedThing	filtration diaphragm assembly	The aggregation, arrangement and bonding together of a set of components to form a filtration diaphragm, a specialized cell-cell junction found between the cells of the excretory system, which provides a barrier for filtration of blood or hemolymph.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-12-12T04:38:40Z					biological_process											owl:Class	
GO:0019973	biolink:NamedThing	interleukin-13 binding	Binding to interleukin-13.	tmpzr1t_l9r_go_relaxed.owl	IL-13 binding													molecular_function											owl:Class	
GO:0140365	biolink:NamedThing	RNP body	A ribonucleoprotein granule located in the cytoplasm of bacteria, minimally containing the RNase E protein and RNA molecules. Bacterial RNP-bodies are similar to eukaryotic P-bodies and stress granules.	tmpzr1t_l9r_go_relaxed.owl	BR-body							pg	2019-07-25T19:31:17Z					cellular_component											owl:Class	
GO:0044181	biolink:NamedThing	filamentous growth of a multicellular organism	The process in which a multicellular organism grows in a threadlike, filamentous shape.	tmpzr1t_l9r_go_relaxed.owl								jl	2009-09-25T10:17:58Z					biological_process											owl:Class	
GO:0032168	biolink:NamedThing	hyphal septin ring	A tight ring-shaped structure that forms in the division plane within hyphae of filamentous fungi at sites where a septum will form; composed of septins as well as septin-associated proteins.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0090588	biolink:NamedThing	protein-phosphocysteine-N-acetylmuramate phosphotransferase system transporter activity	Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein S-phosphocysteine + N-acetylmuramate (out) = protein cysteine + N-acetylmuramate-6-phosphate (in).	tmpzr1t_l9r_go_relaxed.owl								tb	2014-06-04T16:22:31Z					molecular_function											owl:Class	
GO:0090548	biolink:NamedThing	response to nitrate starvation	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of nitrate.	tmpzr1t_l9r_go_relaxed.owl								tb	2013-04-22T13:57:16Z					biological_process											owl:Class	
GO:0035782	biolink:NamedThing	mature natural killer cell chemotaxis	The directed movement of a mature natural killer cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis). A mature natural killer cell is a natural killer cell that is developmentally mature and expresses a variety of inhibitory and activating receptors that recognize MHC class and other stress related molecules.	tmpzr1t_l9r_go_relaxed.owl	activated natural killer cell chemotaxis							bf	2011-04-04T11:23:13Z					biological_process											owl:Class	
GO:0090160	biolink:NamedThing	Golgi to lysosome transport	The directed movement of substances from the Golgi to lysosomes.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-12-08T08:35:13Z					biological_process											owl:Class	
GO:1990756	biolink:NamedThing	ubiquitin ligase-substrate adaptor activity	The binding activity of a molecule that brings together a ubiquitin ligase and its substrate. Usually mediated by F-box BTB/POZ domain proteins.	tmpzr1t_l9r_go_relaxed.owl	protein binding, bridging involved in substrate recognition for ubiquitination|ubiquitin ligase substrate adaptor	https://github.com/geneontology/go-ontology/issues/18655						vw	2015-06-01T08:35:16Z					molecular_function											owl:Class	
GO:0061479	biolink:NamedThing	response to reverse transcriptase inhibitor	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reverse transcriptase inhibitor stimulus.	tmpzr1t_l9r_go_relaxed.owl								dph	2012-11-07T09:10:51Z					biological_process											owl:Class	
GO:0003951	biolink:NamedThing	NAD+ kinase activity	Catalysis of the reaction: ATP + NAD(+) = ADP + 2 H(+) + NADP(+).	tmpzr1t_l9r_go_relaxed.owl	NADK|ATP:NAD+ 2'-phosphotransferase activity|NAD kinase activity|nicotinamide adenine dinucleotide kinase (phosphorylating)|nicotinamide adenine dinucleotide kinase activity|DPN kinase activity				MetaCyc:NAD-KIN-RXN|KEGG_REACTION:R00104|Reactome:R-HSA-197198|RHEA:18629|EC:2.7.1.23|Reactome:R-HSA-8955030									molecular_function											owl:Class	
GO:0102291	biolink:NamedThing	11alpha-hydroxy-beta-amyrin dehydrogenase activity	Catalysis of the reaction: 11alpha-hydroxy-beta-amyrin + O2 + NADPH + H+ = 11-oxo-beta-amyrin + 2 H2O + NADP.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-12682|EC:1.14.14.152|RHEA:31719									molecular_function											owl:Class	
GO:0047684	biolink:NamedThing	arylamine glucosyltransferase activity	Catalysis of the reaction: UDP-glucose + an arylamine = UDP + an N-D-glucosylarylamine.	tmpzr1t_l9r_go_relaxed.owl	UDP-glucose:arylamine N-D-glucosyltransferase activity|UDP glucose-arylamine glucosyltransferase activity|uridine diphosphoglucose-arylamine glucosyltransferase activity|UDPglucose:arylamine N-D-glucosyltransferase activity				MetaCyc:ARYLAMINE-GLUCOSYLTRANSFERASE-RXN|EC:2.4.1.71									molecular_function											owl:Class	
GO:0008825	biolink:NamedThing	cyclopropane-fatty-acyl-phospholipid synthase activity	Catalysis of the reaction: S-adenosyl-L-methionine + phospholipid olefinic fatty acid = S-adenosyl-L-homocysteine + phospholipid cyclopropane fatty acid.	tmpzr1t_l9r_go_relaxed.owl	CFA synthase activity|cyclopropane fatty acid synthase activity|cyclopropane synthetase activity|cyclopropane synthase activity|unsaturated-phospholipid methyltransferase activity|cyclopropane fatty acid synthetase activity|S-adenosyl-L-methionine:unsaturated-phospholipid methyltransferase (cyclizing)				MetaCyc:2.1.1.79-RXN|RHEA:11988|EC:2.1.1.79									molecular_function											owl:Class	
GO:0072444	biolink:NamedThing	response to mitotic DNA replication checkpoint signaling	A process that occurs in response to signals generated as a result of mitotic DNA replication checkpoint signaling.	tmpzr1t_l9r_go_relaxed.owl	response to S-M checkpoint signaling|response to signal involved in mitotic DNA replication checkpoint|S-M checkpoint effector process|response to signal involved in S-M checkpoint|mitotic DNA replication checkpoint effector process							mah	2010-12-08T05:13:27Z			GO:0072447		biological_process											owl:Class	
GO:0002230	biolink:NamedThing	positive regulation of defense response to virus by host	Any host process that results in the promotion of antiviral immune response mechanisms, thereby limiting viral replication.	tmpzr1t_l9r_go_relaxed.owl	activation of antiviral response by host|up-regulation of antiviral response by host|up regulation of antiviral response by host|positive regulation of antiviral response by host|upregulation of antiviral response by host|stimulation of antiviral response by host													biological_process											owl:Class	
GO:0033566	biolink:NamedThing	gamma-tubulin complex localization	Any process in which a gamma-tubulin complex is transported to, or maintained in, a specific location.	tmpzr1t_l9r_go_relaxed.owl	gamma-tubulin complex localisation|establishment and maintenance of gamma-tubulin complex localization													biological_process											owl:Class	
GO:0036352	biolink:NamedThing	histone H2A-K15 ubiquitination	The modification of histone H2A by addition of ubiquitin group at lysine 15 (H2A-K15) in metazoans, and at the equivalent residue in other organisms. Monoubiquitin is first attached to H2A-K15 and K63-linked ubiquitin chains are then extended from this monoubiquitin.	tmpzr1t_l9r_go_relaxed.owl	histone H2A ubiquitination (H2A-K15)							bf	2012-09-19T11:49:03Z					biological_process											owl:Class	
GO:0004163	biolink:NamedThing	diphosphomevalonate decarboxylase activity	Catalysis of the reaction: (R)-5-diphosphomevalonate + ATP = ADP + CO(2) + H(+) + isopentenyl diphosphate + phosphate.	tmpzr1t_l9r_go_relaxed.owl	pyrophosphomevalonate decarboxylase activity|pyrophosphomevalonic acid decarboxylase activity|ATP:(R)-5-diphosphomevalonate carboxy-lyase (adding ATP; isopentenyl-diphosphate-forming)|mevalonate-5-pyrophosphate decarboxylase activity|ATP:(R)-5-diphosphomevalonate carboxy-lyase (dehydrating)|5-pyrophosphomevalonate decarboxylase activity|mevalonate diphosphate decarboxylase activity|mevalonate 5-diphosphate decarboxylase activity|mevalonate pyrophosphate decarboxylase activity				MetaCyc:DIPHOSPHOMEVALONTE-DECARBOXYLASE-RXN|RHEA:23732|EC:4.1.1.33|Reactome:R-HSA-191414|KEGG_REACTION:R01121									molecular_function											owl:Class	
GO:0071000	biolink:NamedThing	response to magnetism	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a magnetic stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to magnetic stimulus							mah	2009-11-04T12:02:03Z					biological_process											owl:Class	
GO:0097660	biolink:NamedThing	SCF-Cdc4 ubiquitin ligase complex	An SCF ubiquitin ligase complex in which the F-box protein is Cdc4 in S. cerevisiae.	tmpzr1t_l9r_go_relaxed.owl								pr	2014-10-06T10:23:13Z					cellular_component											owl:Class	
GO:0103040	biolink:NamedThing	aldose sugar dehydrogenase activity	Catalysis of the reaction: H2O + an aldose + an oxidized electron acceptor = H+ + an aldonate + a reduced electron acceptor.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN0-6371									molecular_function											owl:Class	
GO:0005917	biolink:NamedThing	nephrocyte diaphragm	A specialized cell-cell junction found between nephrocytes of the insect kidney, which is adapted for filtration of hemolymph. The insect nephrocyte is anatomically and functionally similar to the glomerular podocyte of vertebrates.	tmpzr1t_l9r_go_relaxed.owl	nephrocyte junction													cellular_component											owl:Class	
GO:1990755	biolink:NamedThing	mitotic spindle microtubule depolymerization	The removal of tubulin heterodimers from one or both ends of a microtubule that is part of the mitotic spindle.	tmpzr1t_l9r_go_relaxed.owl	mitotic spindle microtubule depolymerisation							mah	2015-05-28T15:42:06Z					biological_process											owl:Class	
GO:0047045	biolink:NamedThing	testosterone 17-beta-dehydrogenase (NADP+) activity	Catalysis of the reaction: NADP+ + testosterone = NADPH + H+ + androst-4-ene-3,17-dione.	tmpzr1t_l9r_go_relaxed.owl	NADP-dependent testosterone-17beta-oxidoreductase activity|17-ketoreductase activity|17beta-hydroxysteroid:NADP+ 17-oxidoreductase activity|testosterone 17beta-dehydrogenase (NADP+)				RHEA:14981|Wikipedia:Testosterone_17beta-dehydrogenase_(NADP+)|EC:1.1.1.64|KEGG_REACTION:R01838|MetaCyc:1.1.1.64-RXN									molecular_function											owl:Class	
GO:0034860	biolink:NamedThing	2-mercaptobenzothiazole desulfurase activity	Catalysis of the reaction: 2-mercaptobenzothiazole + reduced acceptor = benzothiazole + hydrogen sulfide + oxidized acceptor.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r1288|EC:4.4.1.-									molecular_function											owl:Class	
GO:0031759	biolink:NamedThing	Edg-6 sphingosine 1-phosphate receptor binding	Binding to an Edg-6 sphingosine 1-phosphate receptor.	tmpzr1t_l9r_go_relaxed.owl	Edg-6 sphingosine 1-phosphate receptor ligand													molecular_function											owl:Class	
GO:0019010	biolink:NamedThing	farnesoic acid O-methyltransferase activity	Catalysis of the reaction: farnesoic acid + S-adenosyl-methionine = methyl farnesoate + S-adenosyl-L-homocysteine.	tmpzr1t_l9r_go_relaxed.owl	S-adenosyl-methionine:farnesoic acid O-methyltransferase activity													molecular_function											owl:Class	
GO:0090672	biolink:NamedThing	telomerase RNA localization	Any process in which telomerase RNA is transported to, or maintained in, a specific location.	tmpzr1t_l9r_go_relaxed.owl								tb	2015-12-17T14:08:01Z					biological_process											owl:Class	
GO:0018529	biolink:NamedThing	nitrilotriacetate monooxygenase activity	Catalysis of the reaction: nitrilotriacetate + NADH + H+ + O2 = NAD+ + H2O + glyoxylate + iminodiacetate.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0587|EC:1.14.14.10									molecular_function											owl:Class	
GO:0102443	biolink:NamedThing	L-2-hydroxycarboxylate dehydrogenase (NAD+) activity	Catalysis of the reaction: NAD(1-) + a (2S)-2-hydroxycarboxylate <=> NADH(2-) + H+ + a 2-oxo carboxylate.	tmpzr1t_l9r_go_relaxed.owl					RHEA:34555|MetaCyc:RXN-13927|EC:1.1.1.337									molecular_function											owl:Class	
GO:0061768	biolink:NamedThing	magnesium:sodium antiporter activity	Catalysis of the reaction: Na+(in) + Mg2+(out) = Na+(out) + Mg2+(in).	tmpzr1t_l9r_go_relaxed.owl								dph	2016-05-04T14:45:45Z					molecular_function											owl:Class	
GO:0070121	biolink:NamedThing	Kupffer's vesicle development	The progression of the Kupffer's vesicle over time from its initial formation until its mature state. The Kupffer's vesicle is a small but distinctive epithelial sac containing fluid, located midventrally posterior to the yolk cell or its extension, and transiently present during most of the segmentation period.	tmpzr1t_l9r_go_relaxed.owl	KV development													biological_process											owl:Class	
GO:0052338	biolink:NamedThing	disruption by host of symbiont cell wall	The chemical reactions and pathways performed by an organism resulting in the breakdown of the symbiont cell wall. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	catabolism of symbiont cell wall by organism|degradation of symbiont cell wall by organism|disassembly by host of symbiont cell wall													biological_process											owl:Class	
GO:0052336	biolink:NamedThing	modification by host of symbiont cell wall	The process in which an organism effects a change in the structure or function of the symbiont cell wall. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	metabolism of symbiont cell wall by organism													biological_process											owl:Class	
GO:1904068	biolink:NamedThing	G protein-coupled receptor signaling pathway involved in social behavior	Any G protein-coupled receptor signaling pathway that is involved in social behavior.	tmpzr1t_l9r_go_relaxed.owl	G protein coupled receptor protein signalling pathway involved in social behavior|GPCR signalling pathway involved in cooperative behavior|G protein coupled receptor protein signaling pathway involved in cooperative behavior|G-protein-coupled receptor protein signaling pathway involved in social behaviour|G protein coupled receptor protein signalling pathway involved in social behaviour|G protein coupled receptor protein signaling pathway involved in social behavior|G-protein coupled receptor signaling pathway involved in social behaviour|G-protein coupled receptor signaling pathway involved in social behavior|G-protein-coupled receptor protein signalling pathway involved in social behavior|G-protein-coupled receptor protein signaling pathway involved in cooperative behavior|G-protein coupled receptor signalling pathway involved in social behavior|G-protein coupled receptor protein signaling pathway involved in social behaviour|G-protein coupled receptor signalling pathway involved in cooperative behavior|GPCR signaling pathway involved in cooperative behavior|G protein coupled receptor protein signaling pathway involved in social behaviour|G-protein coupled receptor protein signaling pathway involved in cooperative behavior|G-protein-coupled receptor protein signalling pathway involved in social behaviour|G protein coupled receptor protein signalling pathway involved in cooperative behavior|G-protein coupled receptor protein signal transduction involved in cooperative behavior|G-protein coupled receptor signalling pathway involved in social behaviour|GPCR signaling pathway involved in social behaviour|GPCR signalling pathway involved in social behaviour|GPCR signalling pathway involved in social behavior|G-protein coupled receptor protein signal transduction involved in social behavior|G-protein coupled receptor protein signaling pathway involved in social behavior|G-protein coupled receptor protein signal transduction involved in social behaviour|G-protein coupled receptor signaling pathway involved in cooperative behavior|GPCR signaling pathway involved in social behavior|G-protein-coupled receptor protein signalling pathway involved in cooperative behavior|G-protein-coupled receptor protein signaling pathway involved in social behavior							kmv	2015-03-20T01:51:10Z					biological_process											owl:Class	
GO:0010924	biolink:NamedThing	regulation of inositol-polyphosphate 5-phosphatase activity	Any process that modulates the rate or frequency of inositol-polyphosphate 5-phosphatase activity, the catalysis of the reactions: D-myo-inositol 1,4,5-trisphosphate + H2O = myo-inositol 1,4-bisphosphate + phosphate, and 1D-myo-inositol 1,3,4,5-tetrakisphosphate + H2O = 1D-myo-inositol 1,3,4-trisphosphate + phosphate.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0030379	biolink:NamedThing	neurotensin receptor activity, non-G protein-coupled	Combining with neurotensin, a neuropeptide active in the central and peripheral nervous system in mammals, and transmitting the signal from one side of the membrane to the other by a mechanism independent of coupling to G proteins.	tmpzr1t_l9r_go_relaxed.owl	non-G-protein coupled neurotensin receptor activity|non-G-protein-coupled neurotensin receptor activity|neurotensin receptor activity, non-G-protein coupled|neurotensin receptor activity, non G protein coupled|non G protein coupled neurotensin receptor activity													molecular_function											owl:Class	
GO:0035796	biolink:NamedThing	ATP-binding cassette (ABC) transporter complex, transmembrane substrate-binding subunit-containing	A complex for the transport of metabolites into the cell, consisting of 4 subunits: a transmembrane substrate-binding protein (known as the S component), and an energy-coupling module that comprises two ATP-binding proteins (known as the A and A' components) and a transmembrane protein (known as the T component). Transport of the substrate across the membrane is driven by the hydrolysis of ATP.	tmpzr1t_l9r_go_relaxed.owl	energy coupling factor (ECF)-type ABC transporter|energy-coupling factor transporter|ATP-binding cassette (ABC) transporter complex, ECF-type					The ECF-type transporters differs from other types of ABC transporters because the substrate-binding subunit lies integral to the membrane.		bf	2011-04-11T02:02:41Z					cellular_component											owl:Class	
GO:0019452	biolink:NamedThing	L-cysteine catabolic process to taurine	The chemical reactions and pathways resulting in the breakdown of L-cysteine into other compounds, including taurine.	tmpzr1t_l9r_go_relaxed.owl	L-cysteine breakdown to taurine|L-cysteine degradation to taurine													biological_process											owl:Class	
GO:0070915	biolink:NamedThing	lysophosphatidic acid receptor activity	Combining with the phospholipid derivative lysophosphatidic acid, and transmitting the signal across the membrane by activating an associated G-protein.	tmpzr1t_l9r_go_relaxed.owl	LPA receptor activity							mah	2009-09-10T05:05:13Z					molecular_function											owl:Class	
GO:0036437	biolink:NamedThing	Isw1b complex	An Isw1 complex that binds DNA and has nucleosome-stimulated ATPase activity. In S. cerevisiae, contains an Isw1p ATPase subunit in complex with Ioc2p and Ioc4p.	tmpzr1t_l9r_go_relaxed.owl								bf	2013-09-18T16:53:07Z					cellular_component											owl:Class	
GO:0031466	biolink:NamedThing	Cul5-RING ubiquitin ligase complex	A ubiquitin ligase complex in which a cullin from the Cul5 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by an elongin-BC adaptor and a SOCS/BC box protein.	tmpzr1t_l9r_go_relaxed.owl	cullin-RING ligase 5|SCF5 complex|CRL5 complex|CDL5 complex|EC2S complex													cellular_component											owl:Class	
GO:0035273	biolink:NamedThing	phthalate binding	Binding to a phthalate, any ester or salt of phthalic acid.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0050600	biolink:NamedThing	myristoyl-CoA 11-(E) desaturase activity	Catalysis of the reaction: myristoyl-CoA + NAD(P)H + H+ + O2 = (E)-11-tetradecenoyl-CoA + NAD(P)+ + 2 H2O.	tmpzr1t_l9r_go_relaxed.owl	n-tetradecanoyl-CoA,NAD(P)H:O2 oxidoreductase [11-(E) desaturating]|n-tetradecanoyl-CoA,NADPH:O2 oxidoreductase [11-(E) desaturating]				EC:1.14.19.24|RHEA:46396|MetaCyc:1.14.99.31-RXN									molecular_function											owl:Class	
GO:0034792	biolink:NamedThing	hypophosphite dioxygenase activity	Catalysis of the reaction: hypophosphite + 2-oxoglutarate + O2 = succinate + phosphite + CO2.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r1058									molecular_function											owl:Class	
GO:0002327	biolink:NamedThing	immature B cell differentiation	The process in which a precursor cell type acquires the specialized features of an immature B cell.	tmpzr1t_l9r_go_relaxed.owl	immature B lymphocyte differentiation|immature B cell development|immature B-cell differentiation|immature B-lymphocyte differentiation					Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.								biological_process											owl:Class	
GO:0002766	biolink:NamedThing	innate immune response-inhibiting signal transduction	The cascade of processes by which a signal interacts with a receptor, causing a change in the level or activity of a second messenger or other downstream target, and ultimately leading to inhibition of an innate immune response.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1902981	biolink:NamedThing	synthesis of RNA primer involved in mitotic DNA replication	Any synthesis of RNA primer involved in mitotic cell cycle DNA replication.	tmpzr1t_l9r_go_relaxed.owl	synthesis of RNA primer involved in mitotic cell cycle DNA replication							jl	2014-05-06T19:20:00Z			GO:1903458		biological_process											owl:Class	
GO:0047317	biolink:NamedThing	N6-acetyl-beta-lysine transaminase activity	Catalysis of the reaction: 2-oxoglutarate + 3-amino-6-acetamidohexanoate = L-glutamate + 3-oxo-6-acetamidohexanoate.	tmpzr1t_l9r_go_relaxed.owl	epsilon-acetyl-beta-lysine aminotransferase activity|6-acetamido-3-aminohexanoate:2-oxoglutarate aminotransferase activity|N6-acetyl-beta-lysine aminotransferase activity|N(6)-acetyl-beta-lysine aminotransferase activity				MetaCyc:2.6.1.65-RXN|EC:2.6.1.65|RHEA:16889									molecular_function											owl:Class	
GO:0090669	biolink:NamedThing	telomerase RNA stabilization	Prevention of degradation of telomerase RNA (TERC) molecules.	tmpzr1t_l9r_go_relaxed.owl	TERC stabilization							tb	2015-12-17T14:01:11Z					biological_process											owl:Class	
GO:0006962	biolink:NamedThing	male-specific antibacterial humoral response	An immune response against bacteria, specific to males and mediated through a body fluid.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0097260	biolink:NamedThing	eoxin A4 synthase activity	Catalysis of the reaction: leukotriene A4 = eoxin A4.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-2162019			pr	2012-03-08T02:57:23Z					molecular_function											owl:Class	
GO:0097707	biolink:NamedThing	ferroptosis	A programmed cell death characterized morphologically by the presence of smaller than normal mitochondria with condensed mitochondrial membrane densities, reduction or vanishing of mitochondria crista, and outer mitochondrial membrane rupture. Activation of mitochondrial voltage-dependent anion channels and mitogen-activated protein kinases, upregulation of endoplasmic reticulum stress, and inhibition of cystine/glutamate antiporter are involved in the induction of ferroptosis. This process is characterized by the accumulation of lipid peroxidation products and lethal reactive oxygen species (ROS) derived from iron metabolism. Glutathione peroxidase 4 (GPX4), heat shock protein beta-1, and nuclear factor erythroid 2-related factor 2 function as negative regulators of ferroptosis by limiting ROS production and reducing cellular iron uptake, respectively. In contrast, NADPH oxidase and p53 act as positive regulators of ferroptosis by promotion of ROS production and inhibition of expression of SLC7A11 (a specific light-chain subunit of the cystine/glutamate antiporter), respectively. Misregulated ferroptosis has been implicated in multiple physiological and pathological processes.	tmpzr1t_l9r_go_relaxed.owl	iron-dependent programmed cell death							pr	2016-03-03T12:51:18Z					biological_process											owl:Class	
GO:0061824	biolink:NamedThing	cytosolic ciliogenesis	The process in which an axoneme is exposed entirely or partially to the cytoplasm or by which the cytoplasmic portion is assembled or extended. Cytosolic ciliogenesis can occur following compartmentalized ciliogenesis, in which the cilium is formed within a compartment separated from the cytoplasm.	tmpzr1t_l9r_go_relaxed.owl	intracellular ciliogenesis							dph	2017-01-14T14:24:17Z					biological_process											owl:Class	
GO:0038134	biolink:NamedThing	ERBB2-EGFR signaling pathway	A series of molecular signals initiated by binding of a ligand to an epidermal growth factor receptor (EGFR/ERBB1) on the surface of a cell, followed by transmission of the signal by a heterodimeric complex of ERBB2 and EGFR. ERBB2, which does not bind any known ligand, is activated through formation of a heterodimer with another ligand-activated ERBB family member such as EGFR.	tmpzr1t_l9r_go_relaxed.owl	EGFR-HER2 signaling pathway|ERBB2-EGFR signalling pathway							bf	2012-03-30T11:16:28Z					biological_process											owl:Class	
GO:0004427	biolink:NamedThing	inorganic diphosphatase activity	Catalysis of the reaction: diphosphate + H(2)O = H(+) + 2 phosphate.	tmpzr1t_l9r_go_relaxed.owl	inorganic pyrophosphatase activity|pyrophosphate phosphohydrolase activity|diphosphate phosphohydrolase activity				Reactome:R-HSA-71732|Reactome:R-HSA-449937|RHEA:24576|MetaCyc:INORGPYROPHOSPHAT-RXN|KEGG_REACTION:R00004|EC:3.6.1.1|Reactome:R-HSA-6788912									molecular_function											owl:Class	
GO:0044538	biolink:NamedThing	host cell periphery	The part of a cell encompassing the cell cortex, the plasma membrane, and any external encapsulating structures of a host cell.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-03-21T03:26:33Z					cellular_component											owl:Class	
GO:0071120	biolink:NamedThing	alpha4-beta1 integrin-CD47 complex	A protein complex that consists of an alpha4-beta1 integrin complex bound to the cell surface antigen CD47.	tmpzr1t_l9r_go_relaxed.owl	ITGA4-ITGB1-CB47 complex							mah	2009-11-13T02:21:10Z					cellular_component											owl:Class	
GO:0061327	biolink:NamedThing	anterior Malpighian tubule development	The process whose specific outcome is the progression of the anterior Malpighian tubule over time, from its formation to the mature structure. The pair of anterior tubules arise from a dorsal region of the embryonic hindgut and projects forwards through the body cavity. A Malpighian tubule is a fine, thin-walled excretory tubule in insects which connects with the posterior part of the gut.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-09-28T01:23:18Z					biological_process											owl:Class	
GO:0034904	biolink:NamedThing	5-chloro-2-oxopent-4-enoate hydratase activity	Catalysis of the reaction: 5-chloro-2-oxopent-4-enoate + H2O = 5-chloro-4-hydroxy-2-oxopentanate.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r1436									molecular_function											owl:Class	
GO:0051485	biolink:NamedThing	terpenoid biosynthetic process, mevalonate-dependent	The chemical reactions and pathways resulting in the formation of terpenoids via isopentenyl diphosphate, synthesized by the mevalonate pathway. Isopentenyl diphosphate (IPP) is the fundamental unit in terpenoid biosynthesis, and in mevalonate-dependent terpenoid biosynthesis, acetate, in the form of acetyl-CoA, is converted to isopentenyl diphosphate (IPP) through a series of mevalonate intermediates.	tmpzr1t_l9r_go_relaxed.owl	terpene biosynthesis, mevalonate-dependent|terpene biosynthetic process, mevalonate-dependent|terpenoid anabolism, mevalonate-dependent|terpenoid formation, mevalonate-dependent|terpenoid synthesis, mevalonate-dependent													biological_process											owl:Class	
GO:0047590	biolink:NamedThing	5-dehydro-2-deoxygluconokinase activity	Catalysis of the reaction: ATP + 5-dehydro-2-deoxy-D-gluconate = ADP + 6-phospho-5-dehydro-2-deoxy-D-gluconate.	tmpzr1t_l9r_go_relaxed.owl	5-keto-2-deoxyglucono kinase (phosphorylating)|ATP:5-dehydro-2-deoxy-D-gluconate 6-phosphotransferase activity|DKH kinase activity|5-keto-2-deoxygluconokinase activity				MetaCyc:5-DEHYDRO-2-DEOXYGLUCONOKINASE-RXN|EC:2.7.1.92|RHEA:13497									molecular_function											owl:Class	
GO:0070973	biolink:NamedThing	protein localization to endoplasmic reticulum exit site	A process in which a protein is transported to, or maintained in, a location at an endoplasmic reticulum exit site.	tmpzr1t_l9r_go_relaxed.owl	protein localisation to endoplasmic reticulum exit site|protein localization to ER exit site							mah	2009-10-02T12:45:41Z					biological_process											owl:Class	
GO:0032500	biolink:NamedThing	muramyl dipeptide binding	Interacting selectively and non-covalently, in a non-covalent manner, with muramyl dipeptide; muramyl dipeptide is derived from peptidoglycan.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0106299	biolink:NamedThing	resolution phase response	An active host response phase of acute inflammation driven by specialized pro-resolving mediators (SPMs) and signaling pathways, enabling timely tissue regeneration and return of function.	tmpzr1t_l9r_go_relaxed.owl						Acute inflammatory response(s) are self-limited, resolve on their own and classically divide into initiation and resolution phases. SPMs are a superfamily of proresolving mediators that include resolvins (Rvs), protectins (PDs), maresins (MaRs) and lipoxins (LXs).		hjd	2020-08-25T13:54:05Z					biological_process											owl:Class	
GO:0004737	biolink:NamedThing	pyruvate decarboxylase activity	Catalysis of the reaction: a 2-oxo acid = an aldehyde + CO2.	tmpzr1t_l9r_go_relaxed.owl	pyruvic decarboxylase activity|2-oxo-acid carboxy-lyase (aldehyde-forming)|alpha-ketoacid carboxylase activity|alpha-carboxylase activity|2-oxo-acid carboxy-lyase activity				EC:4.1.1.1|MetaCyc:PYRUVATE-DECARBOXYLASE-RXN|RHEA:11628									molecular_function											owl:Class	
GO:0033978	biolink:NamedThing	phosphonopyruvate hydrolase activity	Catalysis of the reaction: 3-phosphonopyruvate + H(2)O = phosphate + pyruvate.	tmpzr1t_l9r_go_relaxed.owl	PPH				EC:3.11.1.3|RHEA:16673|MetaCyc:3.11.1.3-RXN|KEGG_REACTION:R08200									molecular_function											owl:Class	
GO:0045052	biolink:NamedThing	protein insertion into ER membrane by GPI attachment sequence	A process of protein insertion into the endoplasmic reticulum (ER) membrane in which proteins become anchored to the phospholipid bilayer by a covalently attached glycosylphosphatidylinositol (GPI) molecule.	tmpzr1t_l9r_go_relaxed.owl	protein-ER insertion by GPI attachment sequence|protein insertion into ER membrane, GPI attachment sequence mediated|protein insertion into endoplasmic reticulum membrane by GPI attachment sequence|GPI attachment sequence mediated protein insertion into ER membrane|protein-endoplasmic reticulum insertion by GPI attachment sequence													biological_process											owl:Class	
GO:1903350	biolink:NamedThing	response to dopamine	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dopamine stimulus.	tmpzr1t_l9r_go_relaxed.owl								mr	2014-08-19T19:33:26Z					biological_process											owl:Class	
GO:0098817	biolink:NamedThing	evoked excitatory postsynaptic potential	A process that leads to a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell induced by the evoked release of many vesicles of excitatory neurotransmitter at the synapse.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0004415	biolink:NamedThing	hyalurononglucosaminidase activity	Catalysis of the random hydrolysis of (1->4) linkages between N-acetyl-beta-D-glucosamine and D-glucuronate residues in hyaluronate.	tmpzr1t_l9r_go_relaxed.owl	hyaluronidase activity|hyaluronate 4-glycanohydrolase activity|hyaluronoglucosaminidase activity|chondroitinase activity|hyaluronoglucosidase activity|chondroitinase I activity				Reactome:R-HSA-2160874|Reactome:R-HSA-5693356|MetaCyc:3.2.1.35-RXN|Reactome:R-HSA-9036077|Reactome:R-HSA-1793209|Reactome:R-HSA-2318585|Reactome:R-HSA-2160892|EC:3.2.1.35									molecular_function											owl:Class	
GO:0048254	biolink:NamedThing	snoRNA localization	Any process in which small nucleolar RNA is transported to, or maintained in, a specific location.	tmpzr1t_l9r_go_relaxed.owl	small nucleolar RNA localization|establishment and maintenance of snoRNA localization|snoRNA localisation													biological_process											owl:Class	
GO:0005166	biolink:NamedThing	neurotrophin p75 receptor binding	Binding to a neurotrophin p75 receptor.	tmpzr1t_l9r_go_relaxed.owl	neurotrophin p75 receptor ligand													molecular_function											owl:Class	
GO:1905389	biolink:NamedThing	response to leukotriene B4	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leukotriene B4 stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to LTB4							sl	2016-08-18T16:37:24Z					biological_process											owl:Class	
GO:0004677	biolink:NamedThing	DNA-dependent protein kinase activity	DNA dependent catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein.	tmpzr1t_l9r_go_relaxed.owl						This reaction requires the presence of DNA.								molecular_function											owl:Class	
GO:0043383	biolink:NamedThing	negative T cell selection	The process of elimination of immature T cells which react strongly with self-antigens.	tmpzr1t_l9r_go_relaxed.owl	negative T lymphocyte selection|negative T-lymphocyte selection|negative T-cell selection													biological_process											owl:Class	
GO:0098582	biolink:NamedThing	innate vocalization behavior	A vocalisation behavior that is innate, i.e. that does not need to be learned in order to occur.	tmpzr1t_l9r_go_relaxed.owl								dos	2014-01-24T12:47:01Z					biological_process											owl:Class	
GO:1902314	biolink:NamedThing	hydroquinone binding	Binding to hydroquinone.	tmpzr1t_l9r_go_relaxed.owl	quinol binding							bhm	2013-07-22T10:10:12Z					molecular_function											owl:Class	
GO:0030321	biolink:NamedThing	transepithelial chloride transport	The directed movement of chloride ions from one side of an epithelium to the other.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0048658	biolink:NamedThing	anther wall tapetum development	The process whose specific outcome is the progression of the anther wall tapetum over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl	tapetal layer development|tapetum development													biological_process											owl:Class	
GO:0071332	biolink:NamedThing	cellular response to fructose stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fructose stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-12-10T05:37:39Z					biological_process											owl:Class	
GO:1990050	biolink:NamedThing	phosphatidic acid transfer activity	Removes a phosphatidic acid from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle. Phosphatidic acid refers to a glycophospholipids with, in general, a saturated fatty acid bonded to carbon-1, an unsaturated fatty acid bonded to carbon-2, and a phosphate group bonded to carbon-3.	tmpzr1t_l9r_go_relaxed.owl	phosphatidic acid carrier activity|phosphatidic acid transporter activity|intermembrane PA transfer activity|intermembrane phosphatidic acid transfer activity							rb	2013-02-21T00:45:28Z					molecular_function											owl:Class	
GO:0110001	biolink:NamedThing	toxin-antitoxin complex	A bacterial protein complex that neutralises its own toxin by complexing the toxin with the antitoxin. The antitoxin can be either a protein or an RNA. The neutralising toxin-antitoxin complex also acts as a transcriptional repressor of the toxin-antitoxin operon.	tmpzr1t_l9r_go_relaxed.owl						An example is YoeB (P69348) in Escherichia coli in PMID:16109374 (inferred by direct evidence).		kmv						cellular_component											owl:Class	
GO:0047662	biolink:NamedThing	aminobenzoate decarboxylase activity	Catalysis of the reaction: 4(or 2)-aminobenzoate = aniline + CO2.	tmpzr1t_l9r_go_relaxed.owl	aminobenzoate carboxy-lyase (aniline-forming)|aminobenzoate carboxy-lyase activity				EC:4.1.1.24|MetaCyc:AMINOBENZOATE-DECARBOXYLASE-RXN|RHEA:24200									molecular_function											owl:Class	
GO:0009837	biolink:NamedThing	fruit ripening, non-climacteric	A fruit ripening process that does not involve a respiratory burst.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0047550	biolink:NamedThing	2-oxoadipate reductase activity	Catalysis of the reaction: 2-hydroxyadipate + NAD(+) = 2-oxoadipate + H(+) + NADH.	tmpzr1t_l9r_go_relaxed.owl	2-ketoadipate reductase activity|2-hydroxyadipate:NAD+ 2-oxidoreductase activity|alpha-ketoadipate reductase activity				RHEA:14793|EC:1.1.1.172|MetaCyc:2-OXOADIPATE-REDUCTASE-RXN|KEGG_REACTION:R01932									molecular_function											owl:Class	
GO:0099190	biolink:NamedThing	postsynaptic spectrin-associated cytoskeleton organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of spectrin-associated cytoskeleton and associated proteins in the postsynapse.	tmpzr1t_l9r_go_relaxed.owl								dos	2017-12-20T15:34:26Z					biological_process											owl:Class	
GO:0003385	biolink:NamedThing	cell-cell signaling involved in amphid sensory organ development	Any process that mediates the transfer of information from one cell to another and contributes to the progression of an amphid sensory organ over time, from its formation to the mature state.	tmpzr1t_l9r_go_relaxed.owl	cell-cell signalling involved in amphid sensory organ development							dph	2009-12-09T08:55:37Z					biological_process											owl:Class	
GO:0030752	biolink:NamedThing	5-hydroxyfuranocoumarin 5-O-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + 5-hydroxyfuranocoumarin = S-adenosyl-L-homocysteine + 5-methoxyfuranocoumarin.	tmpzr1t_l9r_go_relaxed.owl	BMT activity|furanocoumarin 5-O-methyltransferase activity|bergaptol 5-O-methyltransferase activity|S-adenosyl-L-methionine:5-hydroxyfuranocoumarin 5-O-methyltransferase activity|bergaptol methyltransferase activity|bergaptol O-methyltransferase activity|furanocoumarin 5-methyltransferase activity|S-adenosyl-L-methionine:5-hydroxyfurocoumarin 5-O-methyltransferase activity|S-adenosyl-L-methionine:bergaptol O-methyltransferase activity|S-adenosyl-L-methionine:bergaptolO-methyltransferase activity				EC:2.1.1.69|RHEA:11808|MetaCyc:2.1.1.69-RXN							GO:0030764		molecular_function											owl:Class	
GO:0031778	biolink:NamedThing	type 2 melanin-concentrating hormone receptor binding	Binding to a type 2 melanin-concentrating hormone receptor.	tmpzr1t_l9r_go_relaxed.owl	type 2 melanin-concentrating hormone receptor ligand													molecular_function											owl:Class	
GO:0071477	biolink:NamedThing	cellular hypotonic salinity response	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.	tmpzr1t_l9r_go_relaxed.owl	cellular response to hypotonic salt stress							mah	2009-12-18T11:53:20Z					biological_process											owl:Class	
GO:0102029	biolink:NamedThing	D-lactate dehydrogenase (quinone) activity	Catalysis of the reaction: (R)-lactate + an ubiquinone = pyruvate + an ubiquinol.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:DLACTDEHYDROGFAD-RXN|RHEA:51468|EC:1.1.5.12									molecular_function											owl:Class	
GO:0047244	biolink:NamedThing	N-acetylglucosaminyldiphosphoundecaprenol N-acetyl-beta-D-mannosaminyltransferase activity	Catalysis of the reaction: N-acetyl-D-glucosaminyldiphosphoundecaprenol + UDP-N-acetyl-D-mannosamine = N-acetyl-beta-D-mannosaminyl-1,4-N-acetyl-D-glucosaminyldiphosphoundecaprenol + UDP.	tmpzr1t_l9r_go_relaxed.owl	uridine diphosphoacetyl-mannosamineacetylglucosaminylpyrophosphorylundecaprenol acetylmannosaminyltransferase activity|UDP-N-acetylmannosamine:N-acetylglucosaminyl diphosphorylundecaprenol N-acetylmannosaminyltransferase activity|UDP-N-acetyl-D-mannosamine:N-acetyl-beta-D-glucosaminyldiphosphoundecaprenol beta-1,4-N-acetylmannosaminyltransferase activity|N-acetylmannosaminyltransferase activity				EC:2.4.1.187|RHEA:16053|MetaCyc:TEICHOICSYN2-RXN									molecular_function											owl:Class	
GO:0004736	biolink:NamedThing	pyruvate carboxylase activity	Catalysis of the reaction: ATP + bicarbonate + pyruvate = ADP + 2 H(+) + oxaloacetate + phosphate.	tmpzr1t_l9r_go_relaxed.owl	pyruvic carboxylase activity|pyruvate:carbon-dioxide ligase (ADP-forming)				EC:6.4.1.1|MetaCyc:PYRUVATE-CARBOXYLASE-RXN|Reactome:R-HSA-70501|RHEA:20844|KEGG_REACTION:R00344									molecular_function											owl:Class	
GO:0080097	biolink:NamedThing	L-tryptophan:pyruvate aminotransferase activity	Catalysis of the reaction: L-tryptophan + pyruvate = 3-(indol-3-yl)pyruvate + L-alanine.	tmpzr1t_l9r_go_relaxed.owl					RHEA:27586|MetaCyc:RXN-10139|EC:2.6.1.99	This reaction falls within the larger set of reactions associated with EC:2.6.1.28 (See BRENDA: http://www.brenda-enzymes.org/php/result_flat.php4?ecno=2.6.1.28; note: 3-indole-2-oxopropanoate = indolepyruvate = 3-(indol-3-yl)pyruvate).		dhl	2009-04-23T03:45:23Z					molecular_function											owl:Class	
GO:0097497	biolink:NamedThing	blood vessel endothelial cell delamination	The process of negative regulation of cell adhesion that results in blood vessel endothelial cells splitting off from an existing endothelial sheet.	tmpzr1t_l9r_go_relaxed.owl								pr	2013-08-12T13:48:34Z					biological_process											owl:Class	
GO:1901558	biolink:NamedThing	response to metformin	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a metformin stimulus.	tmpzr1t_l9r_go_relaxed.owl								hp	2012-11-02T09:46:24Z					biological_process											owl:Class	
GO:0140480	biolink:NamedThing	mitotic spindle pole body insertion into the nuclear envelope	A process in which the duplicated mitotic spindle pole body is inserted into a fenestra which opens in the nuclear envelope in early mitosis, and is subsequently tethered to the membrane.	tmpzr1t_l9r_go_relaxed.owl	establishment of spindle pole body localization to nuclear envelope|establishment of spindle pole body localisation in nuclear envelope|establishment of spindle pole body localization in nuclear envelope	https://github.com/geneontology/go-ontology/issues/14887						pg	2020-06-25T14:45:40Z					biological_process											owl:Class	
GO:0071734	biolink:NamedThing	biotin-[pyruvate-carboxylase] ligase activity	Catalysis of the reaction: ATP + biotin + apo-(pyruvate-carboxylase) = AMP + diphosphate + biotin-(pyruvate-carboxylase).	tmpzr1t_l9r_go_relaxed.owl	biotin-pyruvate carboxylase synthetase activity|biotin-[pyruvate carboxylase] ligase activity|biotin-pyruvate-carboxylase ligase activity|biotin-[pyruvate carboxylase] synthetase activity|biotin:apo-pyruvate-carboxylase ligase				EC:6.3.4.-			mah	2010-03-19T02:37:24Z					molecular_function											owl:Class	
GO:0035880	biolink:NamedThing	embryonic nail plate morphogenesis	The process, occurring in the embryo, by which the anatomical structures of a nail plate are generated and organized. The nail plate is the hard and translucent portion of the nail, composed of keratin, and serves to protect the tips of digits.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-05-31T02:38:57Z					biological_process											owl:Class	
GO:0072204	biolink:NamedThing	cell-cell signaling involved in metanephros development	Any process that mediates the transfer of information from one cell to another and contributes to the progression of the metanephros over time, from its formation to the mature organ.	tmpzr1t_l9r_go_relaxed.owl	cell-cell signalling involved in metanephros development							mah	2010-03-18T10:54:36Z					biological_process											owl:Class	
GO:0030386	biolink:NamedThing	ferredoxin-thioredoxin reductase complex	A protein complex that possesses ferredoxin-thioredoxin reductase activity.	tmpzr1t_l9r_go_relaxed.owl	ferredoxin:thioredoxin reductase complex					Note that this term represents a location and not a function; the activity possessed by this complex is mentioned in the definition for the purpose of describing and distinguishing the complex. The function possessed by this complex is represented by the molecular function term 'ferredoxin-thioredoxin reductase activity ; GO:0103012'.								cellular_component											owl:Class	
GO:0047918	biolink:NamedThing	GDP-mannose 3,5-epimerase activity	Catalysis of the reaction: GDP-mannose = GDP-L-galactose.	tmpzr1t_l9r_go_relaxed.owl	GDP-D-mannose:GDP-L-galactose epimerase activity|GDPmannose 3,5-epimerase activity|guanosine 5'-diphosphate D-mannose:guanosine 5'-diphosphate L-galactose epimerase activity				RHEA:11144|EC:5.1.3.18|MetaCyc:RXN-1882									molecular_function											owl:Class	
GO:0033992	biolink:NamedThing	1,5-anhydro-D-fructose dehydratase activity	Catalysis of the reaction: 1,5-anhydro-D-fructose = 1,5-anhydro-4-deoxy-D-glycero-hex-3-en-2-ulose + H2O.	tmpzr1t_l9r_go_relaxed.owl	AF dehydratase activity|1,5-anhydro-D-arabino-hex-2-ulose dehydratase activity|1,5-anhydro-D-fructose 4-dehydratase activity|1,5-anhydro-D-fructose hydro-lyase (ascopyrone-M-forming) activity|1,5-anhydro-D-fructose hydro-lyase activity|AFDH|1,5-anhydro-D-fructose hydrolyase activity				EC:4.2.1.111|MetaCyc:4.2.1.111-RXN|RHEA:15725									molecular_function											owl:Class	
GO:0102939	biolink:NamedThing	3-methoxy-5-hydroxytoluene O-methyltransferase activity	Catalysis of the reaction: 3-methoxy-5-hydroxytoluene + S-adenosyl-L-methionine  = H+ + 3,5-dimethoxytoluene + S-adenosyl-L-homocysteine.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-9018									molecular_function											owl:Class	
GO:0005706	biolink:NamedThing	polytene chromosome ectopic fiber	A thread-like connection joining two regions of ectopically paired polytene chromosomes.	tmpzr1t_l9r_go_relaxed.owl	polytene chromosome ectopic fibre													cellular_component											owl:Class	
GO:0106351	biolink:NamedThing	aspartate dehydrogenase NAD activity	Catalysis of the reaction: L-aspartate + H2O + NAD+ = oxaloacetate + NH3 + NADH+ H+.	tmpzr1t_l9r_go_relaxed.owl					RHEA:11788			hjd	2021-01-20T17:39:50Z					molecular_function											owl:Class	
GO:0038103	biolink:NamedThing	activin receptor antagonist activity involved in negative regulation of nodal signaling pathway	Interacting with an activin receptor to reduce the action of the agonist nodal. A receptor antagonist does not initiate signaling upon binding to a receptor, but instead blocks an agonist from binding to the receptor.	tmpzr1t_l9r_go_relaxed.owl	nodal antagonist activity|activin receptor antagonist activity involved in negative regulation of nodal signalling pathway							bf	2012-02-17T11:30:21Z					molecular_function											owl:Class	
GO:0046994	biolink:NamedThing	oxidoreductase activity, acting on hydrogen as donor, with a quinone or similar compound as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which hydrogen acts as an electron donor and reduces quinone or similar compound.	tmpzr1t_l9r_go_relaxed.owl					EC:1.12.5.-									molecular_function											owl:Class	
GO:0090492	biolink:NamedThing	N,N-Dihydroxy-L-tryptophan decarboxylase activity	Catalyzes the reaction: N,N-Dihydroxy-L-tryptophan = Indole-3-acetaldehyde oxime + CO2 + H2O.	tmpzr1t_l9r_go_relaxed.owl								tb	2012-10-16T16:32:30Z					molecular_function											owl:Class	
GO:0047305	biolink:NamedThing	(R)-3-amino-2-methylpropionate-pyruvate transaminase activity	Catalysis of the reaction: (2R)-3-amino-2-methylpropanoate + pyruvate = 2-methyl-3-oxopropanoate + L-alanine.	tmpzr1t_l9r_go_relaxed.owl	(R)-3-amino-2-methylpropanoate:pyruvate aminotransferase activity|beta-aminoisobutyrate-pyruvate aminotransferase activity|(R)-3-amino-2-methylpropionate--pyruvate aminotransferase activity|(R)-3-amino-2-methylpropanoate transaminase activity|(R)-3-amino-2-methylpropionate transaminase activity|beta-aminoisobutyrate--pyruvate transaminase activity|D-beta-aminoisobutyrate:pyruvate aminotransferase activity|(R)-3-amino-2-methylpropanoate aminotransferase activity|D-3-aminoisobutyrate-pyruvate transaminase activity|D-3-aminoisobutyrate--pyruvate aminotransferase activity|(R)-3-amino-2-methylpropionate-pyruvate aminotransferase activity|D-3-aminoisobutyrate--pyruvate transaminase activity|D-AIBAT activity				Reactome:R-HSA-909780|EC:2.6.1.40|KEGG_REACTION:R02050|RHEA:18393|MetaCyc:2.6.1.40-RXN	Note that this function was EC:2.6.1.61.						GO:0047314		molecular_function											owl:Class	
GO:0102414	biolink:NamedThing	quercetin-3-O-glucoside 1,6-glucosyltransferase activity	Catalysis of the reaction: quercetin-3-glucoside + UDP-alpha-D-glucose(2-) <=> quercetin-3-gentiobioside + UDP.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-13797									molecular_function											owl:Class	
GO:0002136	biolink:NamedThing	tRNA wobble base lysidine biosynthesis	The process in which the carbonyl of cytosine at position 34 of a tRNA is post-transcriptionally replaced by lysine.	tmpzr1t_l9r_go_relaxed.owl						Exclusively located at the anticodon wobble position (i.e., position 34) of eubacterial and some organellar tRNAIle2. This modification converts the codon specificity from AUG to AUA, and it also converts the aminoacylation specificity of the tRNA from methionine to isoleucine. Requires ATP.								biological_process											owl:Class	
GO:0070541	biolink:NamedThing	response to platinum ion	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a platinum stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to platinum													biological_process											owl:Class	
GO:0045772	biolink:NamedThing	positive regulation of autophagosome size	Any process that increases autophagosome size.	tmpzr1t_l9r_go_relaxed.owl	up regulation of autophagic vacuole size|upregulation of autophagic vacuole size|up-regulation of autophagic vacuole size|stimulation of autophagic vacuole size|positive regulation of autophagic vacuole size|activation of autophagic vacuole size													biological_process											owl:Class	
GO:0052869	biolink:NamedThing	arachidonic acid omega-hydroxylase activity	Catalysis of the reaction: arachidonic acid + O2 + NADPH + H+ = 20-HETE + NADP+ + H2O. Arachidonic acid is also known as (5Z,8Z,11Z,14Z)-icosatetraenoic acid, and 20-HETE is also known as (5Z,8Z,11Z,14Z)-20-hydroxyicosa-5,8,11,14-tetraenoic acid.	tmpzr1t_l9r_go_relaxed.owl	arachidonic acid hydroxylase activity|arachidonic acid:oxygen 1-oxidoreductase activity				KEGG_REACTION:R07041|EC:1.14.15.3			ai	2012-01-30T03:05:27Z					molecular_function											owl:Class	
GO:0060273	biolink:NamedThing	crying behavior	The behavior in which an organism sheds tears, often accompanied by non-verbal vocalizations and in response to external or internal stimuli.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0102750	biolink:NamedThing	tetrahydrogeranylgeranyl-chlorophyll a reductase activity	Catalysis of the reaction: chlorophyll a + NADP = tetrahydrogeranylgeranyl-chlorophyll a + NADPH + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-7666									molecular_function											owl:Class	
GO:0052887	biolink:NamedThing	7,9,9'-tricis-neurosporene:quinone oxidoreductase activity	Catalysis of the reaction: 7,9,9'-tri-cis-neurosporene + a quinone = 7,9,7',9'-tetra-cis-lycopene + a quinol.	tmpzr1t_l9r_go_relaxed.owl	ZDS activity|zeta-carotene desaturase activity|9,9'-di-cis-zeta-carotene desaturase activity				MetaCyc:RXN-11357|EC:1.3.5.6|KEGG_REACTION:R09658									molecular_function											owl:Class	
GO:0008738	biolink:NamedThing	L-fuculose-phosphate aldolase activity	Catalysis of the reaction: L-fuculose 1-phosphate = (S)-lactaldehyde + glycerone phosphate.	tmpzr1t_l9r_go_relaxed.owl	L-fuculose-1-phosphate S-lactaldehyde-lyase (glycerone-phosphate-forming)|L-fuculose 1-phosphate aldolase activity|fuculose aldolase activity|L-fuculose-1-phosphate lactaldehyde-lyase activity				EC:4.1.2.17|RHEA:12933|KEGG_REACTION:R02262|MetaCyc:FUCPALDOL-RXN									molecular_function											owl:Class	
GO:1990016	biolink:NamedThing	neck portion of tanycyte	Elongated portion of a tanycyte that sticks into the periventricular layer of neuropil where it appears to contact a blood vessel; characterized by numerous cytoplasmic extensions. A tanycyte is a specialized elongated ventricular ependymal cell that has processes that extend to the outer, or pial, surface of the CNS.	tmpzr1t_l9r_go_relaxed.owl	neck portion				NIF_Subcellular:sao901230115			pr	2012-12-19T15:17:17Z					cellular_component											owl:Class	
GO:0045148	biolink:NamedThing	tripeptide aminopeptidase activity	Catalysis of the hydrolysis of a single N-terminal amino acid residue from a tripeptide.	tmpzr1t_l9r_go_relaxed.owl	lymphopeptidase activity|peptidase T|alanine-phenylalanine-proline arylamidase activity|imidoendopeptidase activity|aminotripeptidase activity|peptidase B|aminoexotripeptidase activity	https://github.com/geneontology/go-ontology/issues/19681			EC:3.4.11.4|MetaCyc:3.4.11.4-RXN									molecular_function											owl:Class	
GO:0071043	biolink:NamedThing	CUT metabolic process	The chemical reactions and pathways involving cryptic unstable transcripts (CUTs), which are transcribed from intergenic regions. Many intergenic regions are heavily transcribed, but the transcripts are rarely detected due to rapid degradation by the nuclear exosome.	tmpzr1t_l9r_go_relaxed.owl								krc	2009-07-29T02:31:31Z					biological_process											owl:Class	
GO:0019415	biolink:NamedThing	acetate biosynthetic process from carbon monoxide	The chemical reactions and pathways resulting in the formation of acetate from other compounds, including carbon monoxide.	tmpzr1t_l9r_go_relaxed.owl	acetate anabolism from carbon monoxide|carbon monoxide dehydrogenase pathway|acetate synthesis from carbon monoxide|acetate formation from carbon monoxide													biological_process											owl:Class	
GO:0047814	biolink:NamedThing	D-arabinokinase activity	Catalysis of the reaction: D-arabinose + ATP = D-arabinose 5-phosphate + ADP.	tmpzr1t_l9r_go_relaxed.owl	ATP:D-arabinose 5-phosphotransferase activity|D-arabinokinase (phosphorylating)				EC:2.7.1.54|KEGG_REACTION:R01573|MetaCyc:D-ARABINOKINASE-RXN|RHEA:24588									molecular_function											owl:Class	
GO:0019281	biolink:NamedThing	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine	The chemical reactions and pathways resulting in the formation of L-methionine from other compounds, including homoserine, via the intermediates O-succinyl-L-homoserine and cystathionine.	tmpzr1t_l9r_go_relaxed.owl	methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine|L-methionine anabolism from homoserine via O-succinyl-L-homoserine and cystathionine|L-methionine formation from homoserine via O-succinyl-L-homoserine and cystathionine|L-methionine synthesis from homoserine via O-succinyl-L-homoserine and cystathionine				MetaCyc:MET-SAM-PWY									biological_process											owl:Class	
GO:0048836	biolink:NamedThing	specification of increased petal number	Any process that increases the number of petals produced in a developing flower.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0102175	biolink:NamedThing	3-beta-hydroxysteroid dehydrogenase/C4-decarboxylase activity	Catalysis of the reaction: a 3beta-hydroxysteroid-4alpha-carboxylate + NAD(+) = a 3-oxosteroid + CO2 + NADH.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-11928|RHEA:34775									molecular_function											owl:Class	
GO:0097494	biolink:NamedThing	regulation of vesicle size	Any process that modulates the size of a vesicle.	tmpzr1t_l9r_go_relaxed.owl								pr	2013-08-06T11:48:51Z					biological_process											owl:Class	
GO:0006242	biolink:NamedThing	dCTP biosynthetic process	The chemical reactions and pathways resulting in the formation of dCTP, deoxycytidine triphosphate.	tmpzr1t_l9r_go_relaxed.owl	dCTP anabolism|dCTP formation|dCTP synthesis|dCTP biosynthesis													biological_process											owl:Class	
GO:1902191	biolink:NamedThing	2-methylbutanoyl-CoA(4-) biosynthetic process	The chemical reactions and pathways resulting in the formation of 2-methylbutanoyl-CoA(4-).	tmpzr1t_l9r_go_relaxed.owl	2-methylbutanoyl-CoA(4-) anabolism|2-methylbutanoyl-CoA(4-) biosynthesis|2-methylbutanoyl-CoA(4-) synthesis|2-methylbutanoyl-CoA(4-) formation							ms	2013-06-06T09:40:25Z					biological_process											owl:Class	
GO:0075284	biolink:NamedThing	asexual sporulation resulting in formation of a multicellular or syncytial spore	The formation of a multicellular or syncytial spore via septations derived from mitosis.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0044197	biolink:NamedThing	Rel homology domain binding	Binding to a Rel Homology Domain (RHD) of a protein. The RHD is found in a family of eukaryotic transcription factors, which includes NF-kappaB, Dorsal, Relish and NFAT.	tmpzr1t_l9r_go_relaxed.owl	RHD binding							jl	2009-10-20T03:57:48Z					molecular_function											owl:Class	
GO:0018511	biolink:NamedThing	2,3-dihydroxy-2,3-dihydro-p-cumate dehydrogenase activity	Catalysis of the reaction: cis-2,3-dihydroxy-2,3-dihydro-p-cumate + NAD(+) = 2,3-dihydroxy-p-cumate + H(+) + NADH.	tmpzr1t_l9r_go_relaxed.owl	cis-2,3-dihydroxy-2,3-dihydro-p-cumate:NAD+ oxidoreductase activity				UM-BBD_reactionID:r0396|MetaCyc:RXN-665|RHEA:23772|EC:1.3.1.58|KEGG_REACTION:R05240									molecular_function											owl:Class	
GO:0099129	biolink:NamedThing	cochlear outer hair cell electromotile response	A rapid, force generating length change of an outer hair cell in response to electical stimulation.  This occurs naturally as during hearing where it serves a source of mechanical amplification.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0106009	biolink:NamedThing	(4S)-4-hydroxy-2-oxoglutarate aldolase activity	Catalysis of the reaction:(4S)-4-hydroxy-2-oxoglutarate = pyruvate + glyoxylate.	tmpzr1t_l9r_go_relaxed.owl					RHEA:35639|EC:4.1.3.42			hjd	2017-04-25T14:14:58Z					molecular_function											owl:Class	
GO:0047964	biolink:NamedThing	glyoxylate reductase (NAD+) activity	Catalysis of the reaction: glycolate + NAD+ = glyoxylate + NADH.	tmpzr1t_l9r_go_relaxed.owl	glyoxylic acid reductase activity|glycolate reductase activity|NADH-dependent glyoxylate reductase activity				MetaCyc:GLYCOLATE-REDUCTASE-RXN|RHEA:18229|EC:1.1.1.26									molecular_function											owl:Class	
GO:0052022	biolink:NamedThing	modulation by symbiont of jasmonic acid levels in host	The alteration by an organism of the levels of jasmonic acid in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	modulation by organism of jasmonic acid levels in other organism involved in symbiotic interaction											GO:0052456		biological_process											owl:Class	
GO:0018788	biolink:NamedThing	atrazine chlorohydrolase activity	Catalysis of the reaction: atrazine + H(2)O = 4-(ethylamino)-2-hydroxy-6-(isopropylamino)-1,3,5-triazine + chloride + H(+).	tmpzr1t_l9r_go_relaxed.owl	AtzA				KEGG_REACTION:R05558|MetaCyc:3.8.1.8-RXN|EC:3.8.1.8|RHEA:11312|UM-BBD_reactionID:r0113									molecular_function											owl:Class	
GO:0019315	biolink:NamedThing	D-allose biosynthetic process	The chemical reactions and pathways resulting in the formation of D-allose, the D-enantiomer of allo-hexose, an aldohexose similar to glucose.	tmpzr1t_l9r_go_relaxed.owl	D-allose formation|D-allose synthesis|D-allose biosynthesis|D-allose anabolism													biological_process											owl:Class	
GO:0018448	biolink:NamedThing	hydroxymethylmethylsilanediol oxidase activity	Catalysis of the reaction: hydroxymethylmethylsilanediol + O2 + 2 H+ + 2 e- = formylmethylsilanediol + 2 H2O.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0638									molecular_function											owl:Class	
GO:0002211	biolink:NamedThing	behavioral defense response to insect	A behavioral response seeking to protect an organism from an a perceived external threat from an insect or insects to that organism.	tmpzr1t_l9r_go_relaxed.owl	behavioural defense response to insect													biological_process											owl:Class	
GO:0071112	biolink:NamedThing	alpha4-beta4 integrin-EMILIN-1 complex	A protein complex that consists of an alpha4-beta4 integrin complex bound to EMILIN-1 (ElastinMicrofibril Interface Located ProteIN).	tmpzr1t_l9r_go_relaxed.owl	ITGA4-ITGB4-EMILIN1 complex							mah	2009-11-13T02:17:11Z					cellular_component											owl:Class	
GO:0047190	biolink:NamedThing	2-acylglycerophosphocholine O-acyltransferase activity	Catalysis of the reaction: 2-acyl-sn-glycero-3-phosphocholine + acyl-CoA = 1,2-diacyl-sn-glycero-3-phosphocholine + CoA.	tmpzr1t_l9r_go_relaxed.owl	2-acylglycerophosphocholine acyltransferase activity|2-acylglycerol-3-phosphorylcholine acyltransferase activity|acyl-CoA:2-acyl-sn-glycero-3-phosphocholine O-acyltransferase activity				KEGG_REACTION:R01319|EC:2.3.1.62|MetaCyc:2.3.1.62-RXN|RHEA:10332									molecular_function											owl:Class	
GO:1990910	biolink:NamedThing	response to hypobaric hypoxia	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension combined with low atmospheric pressure. Hypoxia is defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95% and hypobaric is defined as atmospheric pressure below 0.74 atm (greater than 2,500 m above sea level).	tmpzr1t_l9r_go_relaxed.owl								sl	2015-12-07T19:34:14Z					biological_process											owl:Class	
GO:0101030	biolink:NamedThing	tRNA-guanine transglycosylation	The modification of a tRNA anticodon loop by replacing guanine with queuonine. Reaction is tRNA guanine + queuine = tRNA queuine + guanine.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0019517	biolink:NamedThing	L-threonine catabolic process to D-lactate	The chemical reactions and pathways resulting in the breakdown of L- threonine (the L-enantiomer of 2-amino-3-hydroxybutyric acid) to form the compound methylglyoxal, which is subsequently converted to D-lactate.	tmpzr1t_l9r_go_relaxed.owl	L-threonine catabolic process to pyruvate|L-threonine catabolic process to (R)-lactate|L-threonine catabolism to D-lactate|L-threonine degradation to D-lactate|L-threonine catabolic process to methylglyoxal|L-threonine breakdown to D-lactate|threonine catabolic process to D-lactate				MetaCyc:THRDLCTCAT-PWY									biological_process											owl:Class	
GO:0047566	biolink:NamedThing	3-ketovalidoxylamine C-N-lyase activity	Catalysis of the reaction: 4-nitrophenyl-3-ketovalidamine = 4-nitroaniline + 5-D-(5/6)-5-C-(hydroxymethyl)-2,6-dihydroxycyclohex-2-en-1-one + H(+).	tmpzr1t_l9r_go_relaxed.owl	4-nitrophenyl-3-ketovalidamine 4-nitroaniline-lyase activity|4-nitrophenyl-3-ketovalidamine 4-nitroaniline-lyase [5-D-(5/6)-5-C-(hydroxymethyl)-2,6-dihydroxycyclohex-2-en-1-one-forming]|3-ketovalidoxylamine A C-N-lyase activity|p-nitrophenyl-3-ketovalidamine p-nitroaniline lyase activity				EC:4.3.3.1|RHEA:22768|MetaCyc:3-KETOVALIDOXYLAMINE-C-N-LYASE-RXN|KEGG_REACTION:R04367									molecular_function											owl:Class	
GO:0015361	biolink:NamedThing	low-affinity sodium:dicarboxylate symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: dicarboxylate(out) + Na+(out) = dicarboxylate(in) + Na+(in). In low-affinity transport the transporter is able to bind the solute only if it is present at very high concentrations.	tmpzr1t_l9r_go_relaxed.owl	low affinity sodium:dicarboxylate cotransporter activity|low affinity sodium:dicarboxylate symporter activity				Reactome:R-HSA-433131									molecular_function											owl:Class	
GO:0015648	biolink:NamedThing	lipid-linked peptidoglycan transporter activity	Enables the directed movement of lipid-linked peptidoglycans into, out of or within a cell, or between cells.	tmpzr1t_l9r_go_relaxed.owl	lipid-linked murein transporter activity													molecular_function											owl:Class	
GO:0009974	biolink:NamedThing	zeinoxanthin epsilon hydroxylase activity	Catalysis of the reaction: zeinoxanthin + NADPH + O2 + H+ = lutein + NADP+ + H2O. Adds a hydroxyl group to the epsilon ring of the alpha-carotene.	tmpzr1t_l9r_go_relaxed.owl					EC:1.14.14.158|RHEA:57352|MetaCyc:RXN-5962									molecular_function											owl:Class	
GO:0018480	biolink:NamedThing	5-carboxymethyl-2-hydroxymuconic-semialdehyde dehydrogenase activity	Catalysis of the reaction: 5-carboxymethyl-2-hydroxymuconate semialdehyde + H2O + NAD+ = 5-carboxymethyl-2-hydroxymuconate + NADH + H+.	tmpzr1t_l9r_go_relaxed.owl	carboxymethylhydroxymuconic semialdehyde dehydrogenase activity|5-carboxymethyl-2-hydroxymuconic-semialdehyde:NAD+ oxidoreductase activity				MetaCyc:CHMS-DEHYDROGENASE-RXN|UM-BBD_reactionID:r0365|RHEA:15681|EC:1.2.1.60									molecular_function											owl:Class	
GO:0031143	biolink:NamedThing	pseudopodium	A temporary protrusion or retractile process of a cell, associated with flowing movements of the protoplasm, and serving for locomotion and feeding.	tmpzr1t_l9r_go_relaxed.owl	reticulopodium|axopodium|lobopodium|pseudopod|pseudopodial protrusion	https://github.com/geneontology/go-ontology/issues/21141|https://github.com/geneontology/go-ontology/issues/21139			Wikipedia:Pseudopod									cellular_component											owl:Class	
GO:0009752	biolink:NamedThing	detection of salicylic acid stimulus	The series of events in which a salicylic acid stimulus is received by a cell and converted into a molecular signal.	tmpzr1t_l9r_go_relaxed.owl	perception of salicylic acid stimulus													biological_process											owl:Class	
GO:0043744	biolink:NamedThing	N2-acetyl-L-aminoadipate kinase activity	Catalysis of the reaction: ATP + N-acetyl-L-2-aminoadipate = ADP + N-acetyl-L-2-aminoadipate 6-phosphate.	tmpzr1t_l9r_go_relaxed.owl	acetylaminoadipate kinase activity|N-acetylaminoadipate kinase activity|N-acetyl-L-aminoadipate 5-phosphotransferase activity|[LysW]-aminoadipate kinase				MetaCyc:RXN-5182|RHEA:41944							GO:0043868		molecular_function											owl:Class	
GO:0102102	biolink:NamedThing	homocarnosine synthase activity	Catalysis of the reaction: gamma-aminobutyric acid  + L-histidine  + ATP = H+ + homocarnosine + ADP + hydrogenphosphate.	tmpzr1t_l9r_go_relaxed.owl					EC:6.3.2.11|RHEA:59568|MetaCyc:RXN-11222									molecular_function											owl:Class	
GO:0039627	biolink:NamedThing	T=147 icosahedral capsid	The protein coat that surrounds the infective nucleic acid in some virus particles where the subunits (capsomeres) are arranged to form an icosahedron with T=147 symmetry. T=147 icosahedral capsid is composed of 12 pentameric and 1460 hexameric capsomeres for a total of 8820 capsid proteins.	tmpzr1t_l9r_go_relaxed.owl								bf	2012-08-03T16:18:49Z					cellular_component											owl:Class	
GO:0031464	biolink:NamedThing	Cul4A-RING E3 ubiquitin ligase complex	A ubiquitin ligase complex in which a cullin from the Cul4A subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by an adaptor protein.	tmpzr1t_l9r_go_relaxed.owl	SCF4 complex|CDL4 complex|DCX complex|CRL4 complex|VDC complex|cullin-RING ligase 4A													cellular_component											owl:Class	
GO:0080008	biolink:NamedThing	Cul4-RING E3 ubiquitin ligase complex	A ubiquitin ligase complex in which a cullin from the Cul4 family and a RING domain protein form the catalytic core; substrate specificity is conferred by an adaptor protein.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0102406	biolink:NamedThing	omega-hydroxypalmitate O-sinapoyl transferase activity	Catalysis of the reaction: sinapoyl-CoA + 16-hydroxypalmitate <=> coenzyme A + 16-sinapoyloxypalmitate.	tmpzr1t_l9r_go_relaxed.owl					EC:2.3.1.188|MetaCyc:RXN-13728|RHEA:26470									molecular_function											owl:Class	
GO:0047092	biolink:NamedThing	27-hydroxycholesterol 7-alpha-monooxygenase activity	Catalysis of the reaction: O2 + NADPH + 27-hydroxycholesterol = H2O + NADP+ + 7-alpha,27-dihydroxycholesterol.	tmpzr1t_l9r_go_relaxed.owl	27-hydroxycholesterol 7a-hydroxylase activity|27-hydroxycholesterol 7alpha-hydroxylase activity|27-hydroxycholesterol,NADPH:oxygen oxidoreductase (7alpha-hydroxylating)|27-hydroxycholesterol 7alpha-monooxygenase activity|27-hydroxycholesterol 7-alpha-hydroxylase activity				EC:1.14.14.29|MetaCyc:1.14.13.60-RXN|RHEA:24308									molecular_function											owl:Class	
GO:0018585	biolink:NamedThing	fluorene oxygenase activity	Catalysis of the reaction: fluorene + 2 H+ + 2 e- + O2 = H2O + 9-fluorenol.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0407									molecular_function											owl:Class	
GO:0010751	biolink:NamedThing	negative regulation of nitric oxide mediated signal transduction	Any process that decreases the rate, frequency or extent of nitric oxide mediated signal transduction. Nitric oxide mediated signal transduction is a series of molecular signals mediated by the detection of nitric oxide (NO).	tmpzr1t_l9r_go_relaxed.owl	negative regulation of nitric oxide-mediated signal transduction													biological_process											owl:Class	
GO:0050975	biolink:NamedThing	sensory perception of touch	The series of events required for an organism to receive a touch stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process. The perception of touch in animals is mediated by mechanoreceptors in the skin and mucous membranes and is the sense by which contact with objects gives evidence as to certain of their qualities. Different types of touch can be perceived (for example, light, coarse, pressure and tickling) and the stimulus may be external or internal (e.g. the feeling of a full stomach).	tmpzr1t_l9r_go_relaxed.owl	tactile sense|tactition|taction|perception of touch				Wikipedia:Touch									biological_process											owl:Class	
GO:0060427	biolink:NamedThing	lung connective tissue development	The biological process whose specific outcome is the progression of lung connective tissue from an initial condition to its mature state. This process begins with the formation of lung connective tissue and ends with the mature structure. The lung connective tissue is a material made up of fibers forming a framework and support structure for the lungs.	tmpzr1t_l9r_go_relaxed.owl	pulmonary connective tissue development													biological_process											owl:Class	
GO:0052640	biolink:NamedThing	salicylic acid glucosyltransferase (glucoside-forming) activity	Catalysis of the reaction: salicylic acid + UDP-glucose = salicylic acid 2-O-glucoside + UDP.	tmpzr1t_l9r_go_relaxed.owl	UDP:glucose:SA glucosyltransferase (glucoside-forming) activity|salicylic acid glucosyltransferase activity|UDP:glucose:salicylate glucosyltransferase (glucoside-forming) activity|UDP:glucose:2-hydroxybenzoic acid glucosyltransferase (glucoside-forming) activity|UDP:glucose:salicylic acid glucosyltransferase (glucoside-forming) activity				RHEA:62312|MetaCyc:RXN-11658									molecular_function											owl:Class	
GO:0103107	biolink:NamedThing	castasterone 23-O-glucosyltransferase activity	Catalysis of the reaction: castasterone + UDP-alpha-D-glucose <=> castasterone-23-O-glucoside + UDP + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXNQT-4398									molecular_function											owl:Class	
GO:1905602	biolink:NamedThing	positive regulation of receptor-mediated endocytosis involved in cholesterol transport	Any process that activates or increases the frequency, rate or extent of receptor-mediated endocytosis involved in cholesterol transport.	tmpzr1t_l9r_go_relaxed.owl	upregulation of receptor-mediated endocytosis involved in intracellular cholesterol transport|upregulation of receptor-mediated endocytosis of LDL|upregulation of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport|activation of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport|up regulation of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport|up regulation of receptor-mediated endocytosis of LDL|up regulation of receptor-mediated endocytosis involved in cholesterol transport|positive regulation of receptor-mediated endocytosis involved in intracellular cholesterol transport|positive regulation of receptor-mediated endocytosis of LDL|positive regulation of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport|upregulation of receptor-mediated endocytosis of low-density lipoprotein involved in cholesterol transport|upregulation of receptor-mediated endocytosis involved in cholesterol transport|up-regulation of receptor-mediated endocytosis of low-density lipoprotein involved in cholesterol transport|activation of receptor-mediated endocytosis involved in intracellular cholesterol transport|positive regulation of receptor-mediated endocytosis of low-density lipoprotein involved in cholesterol transport|up regulation of receptor-mediated endocytosis of low-density lipoprotein involved in cholesterol transport|activation of receptor-mediated endocytosis of low-density lipoprotein involved in cholesterol transport|up-regulation of receptor-mediated endocytosis involved in intracellular cholesterol transport|up-regulation of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport|up regulation of receptor-mediated endocytosis involved in intracellular cholesterol transport|up-regulation of receptor-mediated endocytosis of LDL|up-regulation of receptor-mediated endocytosis involved in cholesterol transport|activation of receptor-mediated endocytosis involved in cholesterol transport|activation of receptor-mediated endocytosis of LDL							pr	2016-10-26T13:01:59Z					biological_process											owl:Class	
GO:0050619	biolink:NamedThing	phytochromobilin:ferredoxin oxidoreductase activity	Catalysis of the reaction: (3Z)-phytochromobilin + oxidized ferredoxin = biliverdin IXa + reduced ferredoxin.	tmpzr1t_l9r_go_relaxed.owl	HY2|(3Z)-phytochromobilin:ferredoxin oxidoreductase activity|phytochromobilin synthase activity|PPhiB synthase activity|P-Phi-B synthase activity|PFB synthase activity				RHEA:16377|EC:1.3.7.4|MetaCyc:1.3.7.4-RXN									molecular_function											owl:Class	
GO:1902178	biolink:NamedThing	fibroblast growth factor receptor apoptotic signaling pathway	An apoptotic signaling pathway that starts with a ligand binding to, or being withdrawn from, a fibroblast growth factor receptor (FGFR).	tmpzr1t_l9r_go_relaxed.owl	FGF receptor signalling pathway involved in type I programmed cell death|FGFR signaling pathway involved in programmed cell death by apoptosis|FGFR signaling pathway involved in apoptotic cell death|FGFR signaling pathway involved in apoptotic process|fibroblast growth factor receptor signalling pathway involved in apoptotic process|FGF receptor signalling pathway involved in apoptotic program|FGFR signaling pathway involved in apoptotic program|FGF receptor signaling pathway involved in programmed cell death by apoptosis|fibroblast growth factor receptor signalling pathway involved in apoptotic cell death|fibroblast growth factor receptor signalling pathway involved in apoptotic program|fibroblast growth factor receptor signaling pathway involved in apoptosis|FGFR signaling pathway involved in apoptosis|fibroblast growth factor receptor signaling pathway involved in apoptotic process|FGF receptor signaling pathway involved in type I programmed cell death|FGF receptor signaling pathway involved in apoptotic process|fibroblast growth factor receptor signaling pathway involved in type I programmed cell death|fibroblast growth factor receptor signaling pathway involved in apoptotic programmed cell death|FGF receptor signalling pathway involved in apoptotic programmed cell death|fibroblast growth factor receptor signalling pathway involved in signaling (initiator) caspase activity|FGF receptor signalling pathway involved in programmed cell death by apoptosis|fibroblast growth factor receptor signalling pathway involved in type I programmed cell death|FGF receptor signalling pathway involved in apoptotic process|FGF receptor signaling pathway involved in apoptotic program|fibroblast growth factor receptor signaling pathway involved in apoptotic cell death|fibroblast growth factor receptor signaling pathway involved in signaling (initiator) caspase activity|FGF receptor signalling pathway involved in apoptosis|fibroblast growth factor receptor signalling pathway involved in apoptotic programmed cell death|FGFR signaling pathway involved in type I programmed cell death|FGF receptor signaling pathway involved in apoptosis|FGF receptor signaling pathway involved in signaling (initiator) caspase activity|FGF receptor signaling pathway involved in apoptotic cell death|FGFR signaling pathway involved in signaling (initiator) caspase activity|fibroblast growth factor receptor signaling pathway involved in apoptotic program|fibroblast growth factor receptor signaling pathway involved in programmed cell death by apoptosis|fibroblast growth factor receptor signalling pathway involved in programmed cell death by apoptosis|FGF receptor signalling pathway involved in signaling (initiator) caspase activity|FGF receptor signaling pathway involved in apoptotic programmed cell death|fibroblast growth factor receptor signalling pathway involved in apoptosis|FGFR signaling pathway involved in apoptotic programmed cell death|FGF receptor signalling pathway involved in apoptotic cell death							pm	2013-05-30T13:59:57Z					biological_process											owl:Class	
GO:0016731	biolink:NamedThing	oxidoreductase activity, acting on iron-sulfur proteins as donors, NAD or NADP as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which an iron-sulfur protein acts as a hydrogen or electron donor and reduces NAD or NADP.	tmpzr1t_l9r_go_relaxed.owl					EC:1.18.1.-									molecular_function											owl:Class	
GO:1990483	biolink:NamedThing	Clr6 histone deacetylase complex I''	A histone deacetylase complex involved in chromatin organization. In Schizosaccharomyces pombe this complex consists of Clr6, Nts1, Mug165, and Png3.	tmpzr1t_l9r_go_relaxed.owl								al	2014-09-16T10:40:51Z					cellular_component											owl:Class	
GO:0018499	biolink:NamedThing	cis-2,3-dihydrodiol DDT dehydrogenase activity	Catalysis of the reaction: cis-2,3-dihydrodiol DDT + NADP+ = NADPH + 2,3-dihydroxy DDT.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0451									molecular_function											owl:Class	
GO:0031832	biolink:NamedThing	type 6 serotonin receptor binding	Binding to a type 6 serotonin receptor.	tmpzr1t_l9r_go_relaxed.owl	type 6 serotonin receptor ligand|5-hydroxytryptamine 6 receptor binding													molecular_function											owl:Class	
GO:0030892	biolink:NamedThing	mitotic cohesin complex	A cohesin complex that mediates sister chromatid cohesion during mitosis; has a subunit composition distinct from that of the meiotic cohesin complex.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0050134	biolink:NamedThing	N6-methyl-lysine oxidase activity	Catalysis of the reaction: N(6)-methyl-L-lysine + H(2)O + O(2) = L-lysine + formaldehyde + H(2)O(2).	tmpzr1t_l9r_go_relaxed.owl	N6-methyllysine oxidase activity|epsilon-alkyllysinase activity|6-N-methyl-L-lysine:oxygen oxidoreductase (demethylating)|epsilon-N-methyllysine demethylase activity|N(6)-methyllysine oxidase activity|N6-methyl-L-lysine:oxygen oxidoreductase (demethylating)|epsilon-alkyl-L-lysine:oxygen oxidoreductase activity				KEGG_REACTION:R00612|MetaCyc:N6-METHYL-LYSINE-OXIDASE-RXN|RHEA:23200|EC:1.5.3.4									molecular_function											owl:Class	
GO:0050353	biolink:NamedThing	trimethyllysine dioxygenase activity	Catalysis of the reaction: 2-oxoglutarate + N(6),N(6),N(6)-trimethyl-L-lysine + O(2) = 3-hydroxy-N(6),N(6),N(6)-trimethyl-L-lysine + CO(2) + succinate.	tmpzr1t_l9r_go_relaxed.owl	N6,N6,N6-trimethyl-L-lysine,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating)|trimethyllysine alpha-ketoglutarate dioxygenase activity|TML hydroxylase activity|TMLD activity|TML-alpha-ketoglutarate dioxygenase activity|epsilon-trimethyllysine 2-oxoglutarate dioxygenase activity|6-N,6-N,6-N-trimethyl-L-lysine,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating)|trimethyllysine,2-oxoglutarate dioxygenase activity|TML dioxygenase activity				MetaCyc:TRIMETHYLLYSINE-DIOXYGENASE-RXN|EC:1.14.11.8|RHEA:14181|Reactome:R-HSA-71241|KEGG_REACTION:R03451									molecular_function											owl:Class	
GO:0052749	biolink:NamedThing	glucose-6-phosphate dehydrogenase (coenzyme F420) activity	Catalysis of the reaction: beta-D-glucose 6-phosphate + coenzyme F420 + H+ = 6-O-phosphono-D-glucono-1,5-lactone + reduced coenzyme F420.	tmpzr1t_l9r_go_relaxed.owl	F420-dependent glucose-6-phosphate dehydrogenase activity|D-glucose-6-phosphate:F420 1-oxidoreductase activity|coenzyme F420-dependent glucose-6-phosphate dehydrogenase activity				MetaCyc:RXN-11283|KEGG_REACTION:R09550|RHEA:27294|EC:1.1.98.2			ai	2011-09-21T01:21:54Z					molecular_function											owl:Class	
GO:0061186	biolink:NamedThing	negative regulation of silent mating-type cassette heterochromatin assembly	Any process that decreases the frequency, rate, or extent of chromatin silencing at silent mating-type cassette. Chromatin silencing at silent mating-type cassette is the repression of transcription at silent mating-type loci by altering the structure of chromatin.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of chromatin silencing at silent mating-type cassette	https://github.com/geneontology/go-ontology/issues/19112						dph	2010-07-14T08:59:11Z					biological_process											owl:Class	
GO:0034817	biolink:NamedThing	cis-9,10-dihydroanthracene-9,10-diol dehydrogenase activity	Catalysis of the reaction: cis-9,10-dihydroanthracene-9,10-diol = 9,10-anthraquinone + 4 H+ + 4 e-.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r1144									molecular_function											owl:Class	
GO:0080167	biolink:NamedThing	response to karrikin	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a karrikin stimulus. Karrikins are signaling molecules in smoke from burning vegetation that trigger seed germination for many angiosperms (flowering plants).	tmpzr1t_l9r_go_relaxed.owl								dhl	2010-09-23T05:07:22Z					biological_process											owl:Class	
GO:0031217	biolink:NamedThing	glucan 1,4-beta-glucosidase activity	Catalysis of the hydrolysis of (1->4) linkages in (1->4)-beta-D-glucans, to remove successive glucose units.	tmpzr1t_l9r_go_relaxed.owl	beta-1,4-glucanase activity|beta-1,4-beta-glucanase activity|exo-beta-1,4-glucanase activity|exo-1,4-beta-D-glucosidase activity|exo-1,4-beta-glucanase activity|1,4-beta-D-glucan glucohydrolase activity|exocellulase activity|exo-1,4-beta-glucosidase activity|exo-beta-1,4-glucosidase activity				EC:3.2.1.74|MetaCyc:3.2.1.74-RXN									molecular_function											owl:Class	
GO:0018411	biolink:NamedThing	protein glucuronidation	The modification of a protein by amino acid glucuronidation.	tmpzr1t_l9r_go_relaxed.owl	protein amino acid glucuronidation													biological_process											owl:Class	
GO:0050137	biolink:NamedThing	NADPH peroxidase activity	Catalysis of the reaction: H(2)O(2) + H(+) + NADPH = 2 H(2)O + NADP(+).	tmpzr1t_l9r_go_relaxed.owl	TPNH peroxidase activity|TPN peroxidase activity|NADPH:hydrogen-peroxide oxidoreductase activity|triphosphopyridine nucleotide peroxidase activity|nicotinamide adenine dinucleotide phosphate peroxidase activity|NADP peroxidase activity				KEGG_REACTION:R00113|RHEA:15173|MetaCyc:NADPH-PEROXIDASE-RXN|EC:1.11.1.2									molecular_function											owl:Class	
GO:0007119	biolink:NamedThing	budding cell isotropic bud growth	Unlocalized bud growth such that the entire surface of the bud expands evenly, in a cell that reproduces by budding.	tmpzr1t_l9r_go_relaxed.owl	isotropic bud growth													biological_process											owl:Class	
GO:0030715	biolink:NamedThing	oocyte growth in germarium-derived egg chamber	The increase in volume of an oocyte during the growth phase of the egg chamber, once the egg chamber has left the germarium. An example of this process is found in Drosophila melanogaster.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0071461	biolink:NamedThing	cellular response to redox state	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating redox state. Redox state refers to the balance of oxidized versus reduced forms of electron donors and acceptors in an organelle, cell or organ; plastoquinone, glutathione (GSH/GSSG), and nicotinamide nucleotides (NAD+/NADH and NADP+/NADPH) are among the most important.	tmpzr1t_l9r_go_relaxed.owl	cellular redox signal response							mah	2009-12-18T11:30:21Z					biological_process											owl:Class	
GO:0036074	biolink:NamedThing	metaplastic ossification	Direct ossification in which bone formation occurs as result of the direct transformation of non-bone cells into bone cells without cell division.	tmpzr1t_l9r_go_relaxed.owl	metaplasia					Some intramembranous ossification may also be classified as metaplastic; the former classifies based on tissue type location, and the latter based on mechanism/cell division.		bf	2011-12-19T01:50:35Z					biological_process											owl:Class	
GO:0035124	biolink:NamedThing	embryonic caudal fin morphogenesis	The process, occurring in the embryo, by which the anatomical structures of the caudal fin are generated and organized. The caudal fin is an unpaired medial fin mounted at the caudal end of the fish and is the main fin used for propulsion.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0051675	biolink:NamedThing	isopullulanase activity	Catalysis of the hydrolysis of pullulan to isopanose (6-alpha-maltosylglucose).	tmpzr1t_l9r_go_relaxed.owl	pullulan 4-glucanohydrolase (isopanose-forming) activity				EC:3.2.1.57|MetaCyc:3.2.1.57-RXN									molecular_function											owl:Class	
GO:0039586	biolink:NamedThing	modulation by virus of host PP1 activity	The process in which a virus effects a change in host protein phosphatase-1 (PP1) activity, a serine/threonine phosphatase. Different viruses modulate host PP1 activity to remove phosphates from various cellular substrates and downregulate the host's antiviral response.	tmpzr1t_l9r_go_relaxed.owl	modulation of host PP1 activity by virus|regulation by virus of host PP1 activity				VZ:803			bf	2012-05-04T02:11:05Z					biological_process											owl:Class	
GO:1902439	biolink:NamedThing	cellular response to vanadate(3-)	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vanadate(3-) stimulus.	tmpzr1t_l9r_go_relaxed.owl								di	2013-10-10T10:50:30Z					biological_process											owl:Class	
GO:0061016	biolink:NamedThing	snRNA localization to Cajal body	The directed movement of snRNA, small nuclear ribonucleic acid, to a Cajal body.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-01-29T02:40:50Z					biological_process											owl:Class	
GO:0030628	biolink:NamedThing	pre-mRNA 3'-splice site binding	Binding to a pre-mRNA 3' splice site sequence.	tmpzr1t_l9r_go_relaxed.owl	pre-mRNA 3' splice site binding													molecular_function											owl:Class	
GO:0097056	biolink:NamedThing	selenocysteinyl-tRNA(Sec) biosynthetic process	The chemical reactions and pathways resulting in the formation of selenocysteinyl-tRNA(Sec). This process occurs through the following steps: a unique serine-tRNA with a UGA recognizing anticodon is first aminoacylated with serine; this is then phosphorylated by phosphoseryl-tRNA[Ser]Sec kinase; lastly, selenium is swapped for the phosphate on the serine.	tmpzr1t_l9r_go_relaxed.owl	selenocysteinyl-tRNA(Sec) biosynthesis|selenocysteinyl-tRNA(Sec) formation|selenocysteinyl-tRNA(Sec) anabolism|selenocysteinyl-tRNA(Sec) synthesis							pr	2011-05-25T05:33:19Z					biological_process											owl:Class	
GO:1990864	biolink:NamedThing	response to growth hormone-releasing hormone	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth hormone-releasing hormone stimulus. Growth hormone-releasing hormone regulates the release of growth hormone, as well as some pancreatic proteins, and possibly other proteins.	tmpzr1t_l9r_go_relaxed.owl	response to somatorelin|response to growth hormone-releasing factor|response to GHRF|response to sermorelin|response to GRF|response to somatocrinin|response to somatoliberin							sl	2015-09-25T14:45:31Z					biological_process											owl:Class	
GO:0070049	biolink:NamedThing	endobrevin-SNAP-25-syntaxin-2 complex	A SNARE complex that contains endobrevin (VAMP8), SNAP-25, and syntaxin 2 (or orthologs thereof).	tmpzr1t_l9r_go_relaxed.owl	Stx2-Snap25-Vamp8 complex|SNARE complex (Stx2, Snap25, Vamp8)													cellular_component											owl:Class	
GO:0018647	biolink:NamedThing	phenanthrene 1,2-monooxygenase activity	Catalysis of the reaction: phenanthrene + O2 + NADH + H+ = H2O + NAD+ + phenanthrene-1,2-oxide.	tmpzr1t_l9r_go_relaxed.owl					EC:1.14.13.-|UM-BBD_enzymeID:e0333									molecular_function											owl:Class	
GO:0140302	biolink:NamedThing	pollen-style interaction	The interactions (or cell to cell communication) that occur between the male gametophyte (pollen/pollen tube) and the stylar tissues of the female sporophyte.	tmpzr1t_l9r_go_relaxed.owl								pg	2019-02-22T13:59:33Z					biological_process											owl:Class	
GO:0034825	biolink:NamedThing	tetralin ring-hydroxylating dioxygenase activity	Catalysis of the reaction: tetralin + O2 + NADH + H+ = cis-1,2-dihydroxy-1,2,5,6,7,8-hexahydronaphthalene + NAD+.	tmpzr1t_l9r_go_relaxed.owl					EC:1.14.12.-|UM-BBD_reactionID:r1169									molecular_function											owl:Class	
GO:0098848	biolink:NamedThing	alpha-D-ribose 1-methylphosphonate 5-phosphate C-P-lyase activity	Catalysis of the reaction: alpha-D-ribose 1-methylphosphonate 5-phosphate = alpha-D-ribose 1,2-cyclic phosphate 5-phosphate + methane.	tmpzr1t_l9r_go_relaxed.owl	alpha-D-ribose-1-methylphosphonate-5-phosphate C-P-lyase (methane forming)				EC:4.7.1.1|RHEA:34707									molecular_function											owl:Class	
GO:0018835	biolink:NamedThing	carbon phosphorus lyase activity	Catalysis of the reaction: alkylphosphonic acid = R-CH3 + phosphate. Substrates include aminomethylphosphonic acid (AMPA) (forms methylamine), dimethylphosphinic acid (forms methylphosphonic acid), glyphosate (forms sarcosine) and methylphosphonic acid (forms phosphate).	tmpzr1t_l9r_go_relaxed.owl					EC:4.7.1.-							GO:0009456		molecular_function											owl:Class	
GO:0036510	biolink:NamedThing	trimming of terminal mannose on C branch	The removal of an alpha-1,2-linked mannose from the C-chain of a glycoprotein oligosaccharide in the endoplasmic reticulum.	tmpzr1t_l9r_go_relaxed.owl	conversion of (Man)9(GlcNAc)2 to (Man)8C(GlcNAc)2|conversion of M9 to M8C|glycoprotein mannose trimming on C branch					Consider also annotating to 'mannosyl-oligosaccharide 1,2-alpha-mannosidase activity ; GO:0004571'.		bf	2015-06-11T14:10:52Z					biological_process											owl:Class	
GO:0102473	biolink:NamedThing	eriodictyol dibenzoylmethane tautomer 8C-glucosyltransferase activity	Catalysis of the reaction: eriodictyol dibenzoylmethane tautomer + UDP-alpha-D-glucose <=> 8C-beta-D-glucosyl-2-hydroxyeriodictyol + UDP(3-) + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-14079									molecular_function											owl:Class	
GO:0140483	biolink:NamedThing	kinetochore adaptor activity	The binding activity of a protein that brings the kinetochore and another molecule into contact, permitting those molecules to function in a coordinated way.	tmpzr1t_l9r_go_relaxed.owl	outer kinetochore adaptor activity|inner kinetochore adaptor activity	https://github.com/geneontology/go-ontology/issues/21091|https://github.com/geneontology/go-ontology/issues/19701						pg	2020-06-29T08:53:10Z					molecular_function											owl:Class	
GO:0102149	biolink:NamedThing	farnesylcysteine lyase activity	Catalysis of the reaction: S-[(2E,6E)-farnesyl]-L-cysteine  + O2 + H2O <=> (2-trans,6-trans)-farnesal + L-cysteine  + hydrogen peroxide.	tmpzr1t_l9r_go_relaxed.owl					RHEA:30231|EC:1.8.3.6|MetaCyc:RXN-11623									molecular_function											owl:Class	
GO:0060095	biolink:NamedThing	zinc potentiation of synaptic transmission, glycinergic	Any process that activates or increases the frequency, rate or extent of glycinergic synaptic transmission in the presence of zinc. Glycinergic synaptic transmission is the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glycine.	tmpzr1t_l9r_go_relaxed.owl	zinc potentiation of glycinergic synaptic transmission													biological_process											owl:Class	
GO:0044578	biolink:NamedThing	butyryl-CoA biosynthetic process	The chemical reactions and pathway resulting in the formation of butyryl-CoA.	tmpzr1t_l9r_go_relaxed.owl	butyryl-CoA biosynthesis							jl	2012-04-19T04:23:26Z					biological_process											owl:Class	
GO:0021935	biolink:NamedThing	cerebellar granule cell precursor tangential migration	The early migration of granule cell precursors in which cells move orthogonal to the direction of radial migration and ultimately cover the superficial zone of the cerebellar primordium.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0050546	biolink:NamedThing	4-hydroxyphenylpyruvate decarboxylase activity	Catalysis of the reaction: (4-hydroxyphenyl)pyruvate + H(+) = (4-hydroxyphenyl)acetaldehyde + CO(2).	tmpzr1t_l9r_go_relaxed.owl	4-hydroxyphenylpyruvate carboxy-lyase (4-hydroxyphenylacetaldehyde-forming)|4-hydroxyphenylpyruvate carboxy-lyase activity				RHEA:18697|KEGG_REACTION:R03341|MetaCyc:4.1.1.80-RXN|EC:4.1.1.80									molecular_function											owl:Class	
GO:0034476	biolink:NamedThing	U5 snRNA 3'-end processing	Any process involved in forming the mature 3' end of a U5 snRNA molecule.	tmpzr1t_l9r_go_relaxed.owl	U5 snRNA 3' end processing													biological_process											owl:Class	
GO:0015057	biolink:NamedThing	thrombin-activated receptor activity	A G protein-coupled receptor activity that is activated by cleavage by thrombin, which exposes a tethered ligand corresponding to the new N-terminus, which binds to the receptor and activates it.	tmpzr1t_l9r_go_relaxed.owl	thrombin receptor activity, G-protein coupled|thrombin receptor activity											GO:0010655		molecular_function											owl:Class	
GO:0047326	biolink:NamedThing	inositol tetrakisphosphate 5-kinase activity	Catalysis of the reaction: 1D-myo-inositol 1,3,4,6-tetrakisphosphate + ATP = 1D-myo-inositol 1,3,4,5,6-pentakisphosphate + ADP.	tmpzr1t_l9r_go_relaxed.owl	inositol 1,3,4,6-tetrakisphosphate 5-kinase activity|inositol-tetrakisphosphate 5-kinase activity|ATP:1D-myo-inositol-1,3,4,6-tetrakisphosphate 5-phosphotransferase activity|1D-myo-inositol-tetrakisphosphate 5-kinase activity				MetaCyc:2.7.1.140-RXN|Reactome:R-HSA-1855228|EC:2.7.1.140|RHEA:12717									molecular_function											owl:Class	
GO:0090423	biolink:NamedThing	phytochelatin-metal complex formation	A phytochelatin metabolic process in which a metal is incorporated with phytochelatin to form a complex.	tmpzr1t_l9r_go_relaxed.owl	LWM phytochelatin complex formation|low molecular weight phytochelatin complex formation							tb	2012-04-20T03:46:45Z					biological_process											owl:Class	
GO:0102119	biolink:NamedThing	gibberellin A20 carboxyl methyltransferase activity	Catalysis of the reaction: gibberellin A20 + S-adenosyl-L-methionine  <=> gibberellin A20 methyl ester + S-adenosyl-L-homocysteine.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-11360									molecular_function											owl:Class	
GO:0034664	biolink:NamedThing	Ig heavy chain-bound endoplasmic reticulum chaperone complex	A protein complex that is located in the endoplasmic reticulum (ER) and is formed by the association of an immunoglobulin heavy chain with the proteins of the ER chaperone complex; the latter include BiP, GRP94; CaBP1, protein disulfide isomerase (PDI), ERdj3, cyclophilin B, ERp72, GRP170, UDP-glucosyltransferase, and SDF2-L1.	tmpzr1t_l9r_go_relaxed.owl	immunoglobulin heavy chain-bound endoplasmic reticulum chaperone complex|Ig heavy chain-bound ER chaperone complex													cellular_component											owl:Class	
GO:1990446	biolink:NamedThing	U1 snRNP binding	Binding to a U1 small nuclear ribonucleoprotein particle.	tmpzr1t_l9r_go_relaxed.owl								mah	2014-08-06T09:29:44Z					molecular_function											owl:Class	
GO:0052676	biolink:NamedThing	3-methylbutanol:NAD oxidoreductase activity	Catalysis of the reaction: 3-methylbutanol + NAD+ = 3-methylbutanal + NADH + H+. 3-methylbutanal is also known as isovaleraldehyde.	tmpzr1t_l9r_go_relaxed.owl	3-methylbutanol:NAD+ oxidoreductase activity|3-methylbutyraldehyde reductase (NAD) activity|3-methylbutanal reductase (NAD) activity|isoamyl alcohol oxidase (NAD) activity				RHEA:18529|KEGG_REACTION:R05685			ai	2011-04-12T11:22:42Z					molecular_function											owl:Class	
GO:0008740	biolink:NamedThing	L-rhamnose isomerase activity	Catalysis of the reaction: L-rhamnose = L-rhamnulose.	tmpzr1t_l9r_go_relaxed.owl	L-rhamnose ketol-isomerase activity|L-rhamnose aldose-ketose-isomerase activity|rhamnose isomerase activity				KEGG_REACTION:R02437|RHEA:23160|MetaCyc:RHAMNISOM-RXN|EC:5.3.1.14									molecular_function											owl:Class	
GO:0102528	biolink:NamedThing	7,8,4'-trihydroxyflavone methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine  + 7,8,4'-trihydroxyflavone <=> H+ + S-adenosyl-L-homocysteine  + 7,4'-dihydroxy, 8-methoxyflavone.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-14658									molecular_function											owl:Class	
GO:1902701	biolink:NamedThing	pentose catabolic process to propan-2-ol	The chemical reactions and pathways resulting in the breakdown of pentose to propan-2-ol.	tmpzr1t_l9r_go_relaxed.owl	pentose breakdown to propan-2-ol|pentose degradation to propan-2-ol|pentose catabolic process to isopropyl alcohol|solventogenesis|pentose catabolic process to isopropanol|pentose catabolism to propan-2-ol							tb	2014-02-19T18:28:57Z			GO:1990291		biological_process											owl:Class	
GO:1905350	biolink:NamedThing	Y-shaped link assembly	The aggregation, arrangement and bonding together of a set of components to form a Y-shaped link. Two distinct protein complexes are known to be involved in proper linker assembly: the MKS complex and the NPHP complex. Improper assembly of Y-shaped links may cause malfunctioning of the transition zone as a molecular gate.	tmpzr1t_l9r_go_relaxed.owl	Y-shaped fibre assembly|Y-link assembly|membrane-microtubule complex assembly|Y-link structure formation|Y-shaped fibre formation|membrane-microtubule complex formation|Y-shaped fiber formation|Y-shaped fiber assembly|Y-link formation|Y-link structure assembly|Y-shaped linker assembly|Y-shaped assemblage assembly|Y-shaped link formation|Y-shaped linker formation|Y-shaped assemblage formation							pr	2016-08-04T16:04:26Z					biological_process											owl:Class	
GO:0071206	biolink:NamedThing	establishment of protein localization to juxtaparanode region of axon	The directed movement of a protein to the juxtaparanode region of an axon.	tmpzr1t_l9r_go_relaxed.owl	establishment of protein localisation to juxtaparanode region of axon							mah	2009-11-25T01:15:23Z					biological_process											owl:Class	
GO:0043528	biolink:NamedThing	tRNA (m2G10) methyltransferase complex	A protein complex required for the methylation of the guanosine nucleotide at position 10 (m2G10) in tRNA. In S. cerevisiae, this complex consists of at least two subunits, Trm11p and Trm112p.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0043527	biolink:NamedThing	tRNA methyltransferase complex	A multimeric protein complex involved in the methylation of specific nucleotides in tRNA.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0032788	biolink:NamedThing	saturated monocarboxylic acid metabolic process	The chemical reactions and pathways involving saturated monocarboxylic acids, any organic acid containing one carboxyl (COOH) group or anion (COO-) and fully saturated C-C bonds.	tmpzr1t_l9r_go_relaxed.owl	saturated monocarboxylate metabolic process|saturated monocarboxylic acid metabolism													biological_process											owl:Class	
GO:0050500	biolink:NamedThing	1,3-beta-galactosyl-N-acetylhexosamine phosphorylase activity	Catalysis of the reaction: phosphate + beta-D-galactopyranosyl-(1->3)-N-acetyl-D-glucosamine = N-acetyl-D-glucosamine + alpha-D-galactopyranose 1-phosphate.	tmpzr1t_l9r_go_relaxed.owl	beta-D-galactopyranosyl-(1,3)-N-acetyl-D-hexosamine:phosphate galactosyltransferase activity|beta-1,3-galactosyl-N-acetylhexosamine phosphorylase activity|beta-D-galactopyranosyl-(1->3)-N-acetyl-D-hexosamine:phosphate galactosyltransferase activity				RHEA:20285|EC:2.4.1.211|MetaCyc:2.4.1.211-RXN									molecular_function											owl:Class	
GO:0002201	biolink:NamedThing	somatic diversification of DSCAM-based immune receptors	The somatic process that results in the generation of sequence diversity of the DSCAM-based immune receptors of insects.	tmpzr1t_l9r_go_relaxed.owl						Note that this type of immune receptor may not be limited to insects.								biological_process											owl:Class	
GO:0047533	biolink:NamedThing	2,5-dioxovalerate dehydrogenase (NADP+) activity	Catalysis of the reaction: 2,5-dioxopentanoate + NADP+ + H2O = 2-oxoglutarate + NADPH + H+.	tmpzr1t_l9r_go_relaxed.owl	2,5-dioxopentanoate:NADP+ 5-oxidoreductase activity|2-oxoglutarate semialdehyde dehydrogenase activity|alpha-ketoglutaric semialdehyde dehydrogenase activity				MetaCyc:25-DIOXOVALERATE-DEHYDROGENASE-RXN|RHEA:11296|EC:1.2.1.26									molecular_function											owl:Class	
GO:0006423	biolink:NamedThing	cysteinyl-tRNA aminoacylation	The process of coupling cysteine to cysteinyl-tRNA, catalyzed by cysteinyl-tRNA synthetase. A cysteinyl-tRNA synthetase is a  class-I synthetase. The activated amino acid is transferred to the 2'-OH group of a cysteine-accetping tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0047401	biolink:NamedThing	trithionate hydrolase activity	Catalysis of the reaction: H(2)O + trithionate = H(+) + sulfate + thiosulfate.	tmpzr1t_l9r_go_relaxed.owl	trithionate thiosulfohydrolase activity				MetaCyc:3.12.1.1-RXN|EC:3.12.1.1|KEGG_REACTION:R01930|RHEA:21884									molecular_function											owl:Class	
GO:0008256	biolink:NamedThing	protein histidine pros-kinase activity	Catalysis of the reaction: ATP + protein L-histidine = ADP + protein N(pi)-phospho-L-histidine.	tmpzr1t_l9r_go_relaxed.owl	HK2|protein-histidine pros-kinase activity|ATP:protein-L-histidine Npi-phosphotransferase activity|ATP:protein-L-histidine N-pros-phosphotransferase activity				RHEA:22720|EC:2.7.13.1|MetaCyc:2.7.13.1-RXN									molecular_function											owl:Class	
GO:0042835	biolink:NamedThing	BRE binding	Binding to a BRE RNA element (Bruno response element).	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1903858	biolink:NamedThing	protein localization to old growing cell tip	A process in which a protein is transported to, or maintained in, a location within an old growing cell tip.	tmpzr1t_l9r_go_relaxed.owl	protein localisation to old growing cell tip|protein localization in old growing cell tip|protein localisation in old growing cell tip							mah	2015-02-02T13:53:29Z					biological_process											owl:Class	
GO:0098823	biolink:NamedThing	peptidyl-cysteine modification to S-amindino-L-cysteine	The amidinylation of peptidyl-cysteine to form peptidyl-S-amidino-L-cysteine.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0335									biological_process											owl:Class	
GO:0000253	biolink:NamedThing	3-keto sterol reductase activity	Catalysis of the reaction: a 3-beta-hydroxyl sterol + NADP+ = a 3-keto sterol + NADPH + H(+).	tmpzr1t_l9r_go_relaxed.owl	3-keto-steroid reductase activity|3-KSR activity|3beta-hydroxy-steroid:NADP+ 3-oxidoreductase				MetaCyc:RXN66-24|Reactome:R-HSA-194689|MetaCyc:RXN66-19|MetaCyc:RXN3O-4110|RHEA:18409|MetaCyc:RXN66-319|Reactome:R-HSA-194632|MetaCyc:1.1.1.270-RXN|EC:1.1.1.270|MetaCyc:RXN66-314	Note that zymosterol is cholesta-8,24-dien-3-ol.						GO:0050576		molecular_function											owl:Class	
GO:0097550	biolink:NamedThing	transcription preinitiation complex	A protein-DNA complex composed of proteins binding promoter DNA to form the transcriptional preinitiation complex (PIC), the formation of which is a prerequisite for transcription.	tmpzr1t_l9r_go_relaxed.owl	PIC|preinitiation complex|DNA-templated transcriptional preinitiation complex|transcriptional pre-initiation complex|transcriptional preinitiation complex							pr	2014-01-22T09:33:44Z					cellular_component											owl:Class	
GO:0075343	biolink:NamedThing	modulation by symbiont of abscisic acid levels in host	The alteration by an organism of the levels of abscisic acid in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl						Note that this term is intended for use in annotation of symbiont gene products. For host gene products that regulate abscisic acid levels in the host, consider annotating to 'regulation of abscisic acid mediated signaling ; GO:0009787' or 'regulation of abscisic acid biosynthetic process ; GO:0010115'.								biological_process											owl:Class	
GO:0043738	biolink:NamedThing	reduced coenzyme F420 dehydrogenase activity	Catalysis of the reaction: methanophenazine + reduced coenzyme F420 = dihydromethanophenazine + coenzyme F420.	tmpzr1t_l9r_go_relaxed.owl	1,5-dihydrocoenzyme F420 dehydrogenase activity|F420H2 dehydrogenase activity				MetaCyc:RXN-8106|EC:1.5.98.3|RHEA:54752									molecular_function											owl:Class	
GO:0030288	biolink:NamedThing	outer membrane-bounded periplasmic space	The region between the inner (cytoplasmic or plasma) membrane and outer membrane of organisms with two membranes such as Gram negative bacteria. These periplasmic spaces are relatively thick and contain a thin peptidoglycan layer (PGL), also referred to as a thin cell wall.	tmpzr1t_l9r_go_relaxed.owl	outer membrane bounded periplasmic space|outer membrane-enclosed periplasmic space				Wikipedia:Periplasmic_space									cellular_component											owl:Class	
GO:0018566	biolink:NamedThing	1,2-dihydroxynaphthalene-6-sulfonate 1,8a-dioxygenase activity	Catalysis of the reaction: 1,2-dihydroxynaphthalene-6-sulfonate + O2 = H+ + (Z)-4-(2-hydroxy-5-sulfonatophenyl)-2-oxo-3-butenoate.	tmpzr1t_l9r_go_relaxed.owl	1,2-dihydroxynaphthalene-6-sulphonate 1,8a-dioxygenase activity				EC:1.13.11.-|UM-BBD_reactionID:r0324									molecular_function											owl:Class	
GO:0047647	biolink:NamedThing	alkylacetylglycerophosphatase activity	Catalysis of the reaction: 1-alkyl-2-acetyl-sn-glycerol 3-phosphate + H(2)O = 2-acetyl-1-alkyl-sn-glycerol + phosphate.	tmpzr1t_l9r_go_relaxed.owl	1-alkyl-2-lyso-sn-glycero-3-P:acetyl-CoA acetyltransferase activity|1-alkyl-2-acetyl-sn-glycero-3-phosphate phosphohydrolase activity|alkylacetylglycerophosphate phosphatase activity				EC:3.1.3.59|MetaCyc:ALKYLACETYLGLYCEROPHOSPHATASE-RXN|KEGG_REACTION:R03454|RHEA:18221									molecular_function											owl:Class	
GO:0102836	biolink:NamedThing	1-18:1-2-16:1-monogalactosyldiacylglyceroldesaturase activity	Catalysis of the reaction: 1-18:1-2-16:1-monogalactosyldiacylglycerol + O2 + a reduced electron acceptor <=> 1-18:2-2-16:1-monogalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-8296|EC:1.14.19.23									molecular_function											owl:Class	
GO:0015694	biolink:NamedThing	mercury ion transport	The directed movement of mercury (Hg) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	mercuric ion transport|mercury transport													biological_process											owl:Class	
GO:0016348	biolink:NamedThing	imaginal disc-derived leg joint morphogenesis	The process in which the anatomical structures of an imaginal disc-derived leg joint are generated and organized. The leg joint is a flexible region that separates the rigid sections of a leg to allow movement in a controlled manner. An example of this is found in Drosophila melanogaster.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0030429	biolink:NamedThing	kynureninase activity	Catalysis of the reaction: L-kynurenine + H2O = anthranilate + L-alanine.	tmpzr1t_l9r_go_relaxed.owl	L-kynurenine hydrolase activity|kynurenine hydrolase activity				MetaCyc:KYNURENINASE-RXN|EC:3.7.1.3|RHEA:16813|Reactome:R-HSA-71217									molecular_function											owl:Class	
GO:0047248	biolink:NamedThing	nuatigenin 3-beta-glucosyltransferase activity	Catalysis of the reaction: nuatigenin + UDP-D-glucose = H(+) + nuatigenin 3-beta-D-glucopyranoside + UDP.	tmpzr1t_l9r_go_relaxed.owl	UDP-glucose:(20S,22S,25S)-22,25-epoxyfurost-5-ene-3beta,26-diol 3-O-beta-D-glucosyltransferase activity|nuatigenin 3beta-glucosyltransferase activity|uridine diphosphoglucose-nuatigenin glucosyltransferase activity|UDPglucose:(20S,22S,25S)-22,25-epoxyfurost-5-ene-3beta,26-diol 3-O-beta-D-glucosyltransferase activity				EC:2.4.1.192|KEGG_REACTION:R04577|MetaCyc:2.4.1.192-RXN|RHEA:19329									molecular_function											owl:Class	
GO:0033389	biolink:NamedThing	putrescine biosynthetic process from arginine, using agmatinase	The chemical reactions and pathways resulting in the formation of putrescine, 1,4-diaminobutane, from other compounds, including arginine; in this pathway, arginine is converted to agmatine, and agmatine is converted to putrescine in a single enzymatic step.	tmpzr1t_l9r_go_relaxed.owl	putrescine formation from arginine, using agmatinase|putrescine biosynthesis from arginine, using agmatinase|putrescine anabolism from arginine, using agmatinase|putrescine synthesis from arginine, using agmatinase													biological_process											owl:Class	
GO:0062193	biolink:NamedThing	D-ribose pyranase activity	Catalysis of the reaction: beta-D-ribopyranose = beta-D-ribofuranose.	tmpzr1t_l9r_go_relaxed.owl					RHEA:25432|EC:5.4.99.62			dph	2019-12-09T16:49:07Z					molecular_function											owl:Class	
GO:0047207	biolink:NamedThing	1,2-beta-fructan 1F-fructosyltransferase activity	Catalysis of the reaction: [(1->2)-beta-D-fructosyl](n) + [(1->2)-beta-D-fructosyl](m) = [(1->2)-beta-D-fructosyl](n+1) + [(1->2)-beta-D-fructosyl](m-1).	tmpzr1t_l9r_go_relaxed.owl	1,2-beta-D-fructan 1F-fructosyltransferase activity|2,1-fructan:2,1-fructan 1-fructosyltransferase activity|FFT activity|1,2-beta-D-fructan 1(F)-fructosyltransferase activity|1,2-beta-D-fructan:1,2-beta-D-fructan 1(F)-beta-D-fructosyltransferase activity|2,1-beta-D-fructan:2,1-beta-D-fructan 1-beta-D-fructosyltransferase activity|fructan:fructan fructosyl transferase activity|1,2-beta-fructan 1(F)-fructosyltransferase activity|1,2-beta-D-fructan:1,2-beta-D-fructan 1F-beta-D-fructosyltransferase activity				MetaCyc:2.4.1.100-RXN|EC:2.4.1.100									molecular_function											owl:Class	
GO:0015319	biolink:NamedThing	sodium:inorganic phosphate symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Na+(out) + inorganic phosphate(out) = Na+(in) + inorganic phosphate(in).	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0016430	biolink:NamedThing	tRNA (adenine-N6-)-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing N6-methyladenine.	tmpzr1t_l9r_go_relaxed.owl	S-adenosyl-L-methionine:tRNA (adenine-6-N-)-methyltransferase activity|S-adenosyl-L-methionine:tRNA (adenine-N6-)-methyltransferase activity				RHEA:16785|MetaCyc:TRNA-ADENINE-N6--METHYLTRANSFERASE-RXN|EC:2.1.1.55									molecular_function											owl:Class	
GO:0033445	biolink:NamedThing	AGU codon-amino acid adaptor activity	A triplet codon-amino acid adaptor activity that recognizes an AGU codon.	tmpzr1t_l9r_go_relaxed.owl	AGT codon-amino acid adaptor activity|serine tRNA					Note that in the standard genetic code, AGT codes for serine.								molecular_function											owl:Class	
GO:0002297	biolink:NamedThing	T-helper 2 cell lineage commitment	The process in which a CD4-positive, alpha-beta T cell becomes committed to becoming a T-helper 2 cell, a CD4-positive, alpha-beta T cell specialized to promote immunological processes often associated with resistance to extracellular organisms such as helminths, enhanced production of particular antibody isotypes, and pathological conditions such as allergy.	tmpzr1t_l9r_go_relaxed.owl	T-helper 2 cell fate commitment|Th2 fate commitment													biological_process											owl:Class	
GO:0048900	biolink:NamedThing	anterior lateral line neuromast primordium migration	The migration of a cluster of a relatively undifferentiated cell along the developing anterior lateral line, originating from cranial ectodermal placodes situated between the eye and the ear. The neuromast primordium deposits proneuromasts along the lateral line, from which the neuromasts will develop.	tmpzr1t_l9r_go_relaxed.owl	ALL neuromast primordium migration													biological_process											owl:Class	
GO:0098033	biolink:NamedThing	icosahedral viral capsid, neck fiber	A fiber attached to the neck at the base of some icosahedral viral capsids.	tmpzr1t_l9r_go_relaxed.owl								bm	2012-07-19T15:07:39Z					cellular_component											owl:Class	
GO:0034400	biolink:NamedThing	gerontoplast	A plastid found in senescing, formerly green tissues that is derived from a chloroplast that undergoes an organized developmental program of senescence.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0097233	biolink:NamedThing	alveolar lamellar body membrane	The lipid bilayer surrounding an alveolar lamellar body, a specialized secretory organelle found in type II pneumocytes and involved in the synthesis, secretion, and reutilization of pulmonary surfactant.	tmpzr1t_l9r_go_relaxed.owl								pr	2012-01-26T10:30:24Z					cellular_component											owl:Class	
GO:0097208	biolink:NamedThing	alveolar lamellar body	A specialized secretory organelle found in type II pneumocytes and involved in the synthesis, secretion, and reutilization of pulmonary surfactant.	tmpzr1t_l9r_go_relaxed.owl								pr	2012-01-04T02:33:04Z					cellular_component											owl:Class	
GO:0034777	biolink:NamedThing	recycling endosome lumen	The volume enclosed by the membranes of a recycling endosome.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:1904693	biolink:NamedThing	midbrain morphogenesis	The developmental process by which a midbrain is generated and organized.	tmpzr1t_l9r_go_relaxed.owl	mesencephalon morphogenesis|MB morphogenesis							bf	2015-09-29T09:15:28Z					biological_process											owl:Class	
GO:1904977	biolink:NamedThing	lymphatic endothelial cell migration	The orderly movement of a lymphatic endothelial cell from one site to another in the wall of a lymphatic vessel.	tmpzr1t_l9r_go_relaxed.owl								dgh	2016-02-18T20:49:43Z					biological_process											owl:Class	
GO:0021860	biolink:NamedThing	pyramidal neuron development	The progression of a pyramidal neuron from its initial formation to its mature state.	tmpzr1t_l9r_go_relaxed.owl	projection neuron development													biological_process											owl:Class	
GO:0009972	biolink:NamedThing	cytidine deamination	The removal of amino group in the presence of water.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0097482	biolink:NamedThing	muscle cell postsynaptic specialization	A postsynaptic specialization that is part of a neuromuscular junction.	tmpzr1t_l9r_go_relaxed.owl	muscle cell postsynaptic density|muscle fiber postsynaptic density							pr	2013-07-02T09:47:40Z					cellular_component											owl:Class	
GO:0061155	biolink:NamedThing	pulmonary artery endothelial tube morphogenesis	The process in which the anatomical structures of a tube are generated and organized from the pulmonary artery endothelium. An pulmonary artery endothelium is an epithelium that lines the pulmonary artery.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-06-15T09:09:04Z					biological_process											owl:Class	
GO:0048564	biolink:NamedThing	photosystem I assembly	The aggregation, arrangement and bonding together of a set of components to form a photosystem I complex on the thylakoid membrane.	tmpzr1t_l9r_go_relaxed.owl												GO:0010251		biological_process											owl:Class	
GO:1905060	biolink:NamedThing	calcium:cation antiporter activity involved in regulation of postsynaptic cytosolic calcium ion concentration	Any calcium:cation antiporter activity that is involved in regulation of postsynaptic cytosolic calcium ion concentration.	tmpzr1t_l9r_go_relaxed.owl	calcium:cation antiporter activity involved in regulation of postsynaptic cytosolic calcium ion levels							dos	2016-03-18T12:32:17Z					molecular_function											owl:Class	
GO:0009783	biolink:NamedThing	photosystem II antenna complex	The antenna complex of photosystem II. A photosystem has two closely linked components, an antenna containing light-absorbing pigments and a reaction center. Each antenna contains one or more light-harvesting complexes (LHCs).	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:1903627	biolink:NamedThing	regulation of dUTP diphosphatase activity	Any process that modulates the frequency, rate or extent of dUTP diphosphatase activity.	tmpzr1t_l9r_go_relaxed.owl	regulation of dUTP nucleotidohydrolase activity|regulation of dUTPase activity|regulation of desoxyuridine 5'-triphosphate nucleotidohydrolase activity|regulation of dUTP pyrophosphatase activity|regulation of desoxyuridine 5'-triphosphatase activity|regulation of deoxyuridine-triphosphatase activity							sl	2014-11-20T00:00:36Z					biological_process											owl:Class	
GO:0071355	biolink:NamedThing	cellular response to interleukin-9	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-9 stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to IL-9							mah	2009-12-11T02:51:26Z					biological_process											owl:Class	
GO:0060901	biolink:NamedThing	regulation of hair cycle by canonical Wnt signaling pathway	The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes that modulates the rate, frequency or extent of the hair cycle.	tmpzr1t_l9r_go_relaxed.owl	regulation of hair cycle by canonical Wnt receptor signaling pathway|regulation of hair cycle by canonical Wnt-activated signaling pathway|regulation of hair cycle by Wnt receptor signaling pathway through beta-catenin|regulation of hair cycle by canonical Wnt receptor signalling pathway							dph	2009-08-13T02:41:10Z					biological_process											owl:Class	
GO:0033012	biolink:NamedThing	porosome	A permanent cup-shaped structure at the cell plasma membrane in secretory cells. Following a secretory stimulus, secretory vesicles transiently dock and fuse at the base of porosomes and release intravesicular contents dictated by the turgor pressure generated from the swelling of secretory vesicles.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Porosome									cellular_component											owl:Class	
GO:0036131	biolink:NamedThing	prostaglandin D2 11-ketoreductase activity	Catalysis of the reaction: prostaglandin D2 + H+ + NADPH -> 11-epi-prostaglandin F2alpha + NADP+.	tmpzr1t_l9r_go_relaxed.owl	PGD2 11-ketoreductase|prostaglandin 11-keto reductase				KEGG_REACTION:R02799|RHEA:45316|EC:1.1.1.188|Reactome:R-HSA-2161614			bf	2012-03-05T10:27:29Z					molecular_function											owl:Class	
GO:0021640	biolink:NamedThing	trochlear nerve maturation	A developmental process, independent of morphogenetic (shape) change, that is required for the trochlear nerve to attain its fully functional state. The trochlear nerve is a motor nerve and is the only cranial nerve to exit the brain dorsally. The trochlear nerve innervates the superior oblique muscle.	tmpzr1t_l9r_go_relaxed.owl	CN IV maturation													biological_process											owl:Class	
GO:0031071	biolink:NamedThing	cysteine desulfurase activity	Catalysis of the reaction: L-cysteine + [enzyme]-cysteine = L-alanine + [enzyme]-S-sulfanylcysteine.	tmpzr1t_l9r_go_relaxed.owl	cysteine desulfurylase activity|NIFS|IscS|SufS|L-cysteine:enzyme cysteine sulfurtransferase activity				Reactome:R-HSA-947514|EC:2.8.1.7|Reactome:R-HSA-1362408|RHEA:43892									molecular_function											owl:Class	
GO:0031993	biolink:NamedThing	light transducer activity	Absorbing energy from one or more photons and transferring their energy to another molecule, usually a protein, within the cell.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0000301	biolink:NamedThing	retrograde transport, vesicle recycling within Golgi	The retrograde movement of substances within the Golgi, mediated by COP I vesicles. Cis-Golgi vesicles are constantly moving forward through the Golgi stack by cisternal progression, eventually becoming trans-Golgi vesicles. They then selectively transport membrane and luminal proteins from the trans- to the medial-Golgi while leaving others behind in the trans-Golgi cisternae; similarly, they selectively move proteins from the medial- to the cis-Golgi.	tmpzr1t_l9r_go_relaxed.owl	retrograde (vesicle recycling within Golgi) transport													biological_process											owl:Class	
GO:0021717	biolink:NamedThing	inferior olivary nucleus maturation	A developmental process, independent of morphogenetic (shape) change, that is required for the inferior olivary nucleus to attain its fully functional state. The inferior olivary nucleus is a capsule-shaped structure in the ventral medulla located just lateral and dorsal to the medullary pyramids. Neurons in the inferior olivary nucleus are the source of climbing fiber input to the cerebellar cortex; these neurons have been implicated in various functions, such as learning and timing of movements.	tmpzr1t_l9r_go_relaxed.owl	inferior olive maturation													biological_process											owl:Class	
GO:0002446	biolink:NamedThing	neutrophil mediated immunity	Any process involved in the carrying out of an immune response by a neutrophil.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0090104	biolink:NamedThing	pancreatic epsilon cell differentiation	The process in which relatively unspecialized cells acquire specialized structural and functional features of a pancreatic epsilon cell. A pancreatic epsilon cell is a cell in the pancreas that secretes ghrelin.	tmpzr1t_l9r_go_relaxed.owl	pancreatic E cell differentiation							tb	2009-11-18T11:48:52Z					biological_process											owl:Class	
GO:0061446	biolink:NamedThing	endocardial cushion cell fate determination	The process involved in endocardial cushion cell fate commitment. Once determination has taken place, a cell becomes committed to differentiate down a particular pathway regardless of its environment.	tmpzr1t_l9r_go_relaxed.owl								dph	2012-03-13T09:22:13Z					biological_process											owl:Class	
GO:0006794	biolink:NamedThing	phosphorus utilization	A series of processes that forms an integrated mechanism by which a cell or an organism detects the depletion of primary phosphorus source and then activates genes to scavenge the last traces of the primary phosphorus source and to transport and metabolize alternative phosphorus sources. The utilization process begins when the cell or organism detects phosphorus levels, includes the phosphorus-containing substances, and ends when phosphorus is incorporated into the cell or organism's metabolism.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0072192	biolink:NamedThing	ureter epithelial cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of an epithelial cell in the urothelium. The urothelium is the epithelial tube of the ureter.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-03-01T01:53:17Z					biological_process											owl:Class	
GO:0060717	biolink:NamedThing	chorion development	The biological process whose specific outcome is the progression of a chorion from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure. The chorion is an extraembryonic membrane.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-06-11T02:37:50Z					biological_process											owl:Class	
GO:0044515	biolink:NamedThing	envenomation resulting in positive regulation of glucagon-like peptide receptor 1 activity in other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant positive regulation of glucagon-like peptide receptor 1 activity in of the bitten organism.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-02-26T11:08:08Z					biological_process											owl:Class	
GO:0038111	biolink:NamedThing	interleukin-7-mediated signaling pathway	A series of molecular signals initiated by the binding of interleukin-7 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.	tmpzr1t_l9r_go_relaxed.owl	interleukin-7-mediated signalling pathway|IL-7-mediated signaling pathway							bf	2012-03-22T10:19:27Z					biological_process											owl:Class	
GO:0061354	biolink:NamedThing	planar cell polarity pathway involved in pericardium morphogenesis	The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors including C-Jun N-terminal kinase (JNK) to modulate cytoskeletal elements and control cell polarity that contributes to the shaping of the pericardium.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-10-01T03:12:53Z					biological_process											owl:Class	
GO:0034466	biolink:NamedThing	chromaffin granule lumen	The volume enclosed by the membrane of a chromaffin granule.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0021616	biolink:NamedThing	glossopharyngeal nerve formation	The process that gives rise to the glossopharyngeal nerve. This process pertains to the initial formation of a structure from unspecified parts. Various sensory and motor branches of the glossopharyngeal nerve supply nerve connections to the pharynx and back of the tongue. The branchial motor component contains motor fibers that innervate muscles that elevate the pharynx and larynx, and the tympanic branch supplies parasympathetic fibers to the otic ganglion.	tmpzr1t_l9r_go_relaxed.owl	CN IX formation|CN IX biosynthesis													biological_process											owl:Class	
GO:0004341	biolink:NamedThing	gluconolactonase activity	Catalysis of the reaction: D-glucono-1,5-lactone + H2O = D-gluconate.	tmpzr1t_l9r_go_relaxed.owl	lactonase activity|D-glucono-1,5-lactone lactonohydrolase activity|aldonolactonase activity|glucono-delta-lactonase activity|gulonolactonase activity				RHEA:10440|EC:3.1.1.17|MetaCyc:GLUCONOLACT-RXN									molecular_function											owl:Class	
GO:0060134	biolink:NamedThing	prepulse inhibition	The process in which a startle magnitude is reduced when the startling stimulus is preceded by a low-intensity prepulse.	tmpzr1t_l9r_go_relaxed.owl	pre-pulse inhibition|PPI				Wikipedia:Prepulse_inhibition									biological_process											owl:Class	
GO:0072275	biolink:NamedThing	metanephric glomerulus morphogenesis	The process in which the anatomical structures of the metanephric glomerulus are generated and organized. The metanephric glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney, or metanephros.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-04-01T02:46:58Z					biological_process											owl:Class	
GO:0061230	biolink:NamedThing	mesonephric juxtaglomerulus cell fate commitment	The process in which the developmental fate of a cell becomes restricted such that it will develop into a mesonephric juxtaglomerulus cell.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-08-19T02:36:23Z					biological_process											owl:Class	
GO:0003399	biolink:NamedThing	cytoneme morphogenesis	The process in which the anatomical structures of a cytoneme are shaped. A cytoneme is a long, thin and polarized actin-based cytoplasmic extension that projects from a cell.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-12-09T10:03:32Z					biological_process											owl:Class	
GO:0004111	biolink:NamedThing	creatine kinase activity	Catalysis of the reaction: ATP + creatine = N-phosphocreatine + ADP + 2 H(+).	tmpzr1t_l9r_go_relaxed.owl	creatine phosphotransferase activity|MiMi-CK|ATP:creatine N-phosphotransferase activity|MM-CK|phosphocreatine kinase activity|CK-BB|creatine phosphokinase activity|CK-MB|CK|ATP:creatine phosphotransferase activity|MB-CK|CK-MM|Mi-CK|BB-CK|adenosine triphosphate-creatine transphosphorylase activity|CKMiMi				RHEA:17157|Reactome:R-HSA-200318|EC:2.7.3.2|Reactome:R-HSA-200326|MetaCyc:CREATINE-KINASE-RXN|KEGG_REACTION:R01881									molecular_function											owl:Class	
GO:0017119	biolink:NamedThing	Golgi transport complex	A  multisubunit tethering complex of the CATCHR family (complexes associated with tethering containing helical rods) that has a role in tethering vesicles to the Golgi prior to fusion. Composed of 8 subunits COG1-8.	tmpzr1t_l9r_go_relaxed.owl	Sec34/35 complex|COG complex|conserved oligomeric Golgi complex													cellular_component											owl:Class	
GO:0060055	biolink:NamedThing	angiogenesis involved in wound healing	Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels and contribute to the series of events that restore integrity to a damaged tissue, following an injury.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0003208	biolink:NamedThing	cardiac ventricle morphogenesis	The process in which the cardiac ventricle is generated and organized. A cardiac ventricle receives blood from a cardiac atrium and pumps it out of the heart.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-10-13T09:38:44Z					biological_process											owl:Class	
GO:0007412	biolink:NamedThing	axon target recognition	The process in which an axon recognizes and binds to a set of cells with which it may form stable connections.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0019197	biolink:NamedThing	phosphoenolpyruvate-dependent sugar phosphotransferase complex	Includes phosphoenolpyruvate-protein phosphatase (enzyme I of the phosphotransferase system) and protein-N(PI)-phosphohistidine-sugar phosphotransferase (enzyme II of the phosphotransferase system).	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0043663	biolink:NamedThing	host bacteroid-containing symbiosome	A symbiosome containing any of various structurally modified bacteria, such as those occurring on the root nodules of leguminous plants, of a host cell.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0030315	biolink:NamedThing	T-tubule	Invagination of the plasma membrane of a muscle cell that extends inward from the cell surface around each myofibril. The ends of T-tubules make contact with the sarcoplasmic reticulum membrane.	tmpzr1t_l9r_go_relaxed.owl	triad|transverse tubule				Wikipedia:T-tubule									cellular_component											owl:Class	
GO:0035643	biolink:NamedThing	L-DOPA receptor activity	Combining with L-DOPA to initiate a change in cell activity. L-DOPA is the modified amino acid (2S)-2-amino-3-(3,4-dihydroxyphenyl) propanoic acid, and is the precursor to dopamine, norepinephrine (noradrenaline) and epinephrine.	tmpzr1t_l9r_go_relaxed.owl	L-beta-(3,4-Dihydroxyphenyl)alanine receptor activity							bf	2011-01-20T10:34:23Z					molecular_function											owl:Class	
GO:0072122	biolink:NamedThing	extraglomerular mesangial cell proliferation	The multiplication or reproduction of extraglomerular glomerular mesangium cells by cell division, resulting in the expansion of their population. Extraglomerular mesangial cells (also known as lacis cells, Goormaghtigh cells) are light-staining cells in the kidney found outside the glomerulus, near the vascular pole and macula densa.	tmpzr1t_l9r_go_relaxed.owl	lacis cell proliferation|Goormaghtigh proliferation							mah	2010-02-22T01:42:23Z					biological_process											owl:Class	
GO:0098677	biolink:NamedThing	virion maturation	Maturation of a virion after separation from the host cell. Not all viruses mature after separation.  In those that do, maturation typically involves rearangement and/or cleavage of viral proteins, resulting in the virion becoming competent for reinfection.	tmpzr1t_l9r_go_relaxed.owl	viral particle maturation|virus particle maturation				VZ:1946|UniProtKB-KW:KW-0917			dos	2017-01-19T12:49:22Z					biological_process											owl:Class	
GO:0045496	biolink:NamedThing	male analia development	The process whose specific outcome is the progression of the analia of the male over time, from formation to the mature structure. The analia is the posterior-most vertral appendage that develops from the genital disc. An example of this process is found in Drosophila melanogaster.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0062229	biolink:NamedThing	regulation of larval somatic muscle development	Any process that modulates the rate, frequency or extent of larval somatic muscle development.	tmpzr1t_l9r_go_relaxed.owl								dph	2020-03-16T13:42:44Z					biological_process											owl:Class	
GO:0097557	biolink:NamedThing	right posteriolateral flagellum	A cilium (also called flagellum) found in Giardia species (trophozoite stage). It is nucleated by the right posteriolateral basal body and extends cytoplasmically toward the cell posterior, marking the right anterior boundary of the lateral shield and the right lateral region of the funis before exiting at the right lateral region of the cell body.	tmpzr1t_l9r_go_relaxed.owl	right posteriolateral cilium|right posterolateral flagellum|right posterolateral cilium					Note that we deem cilium and microtubule-based flagellum to be equivalent; the primary term name reflects frequency of use. Also note that, due to the asymmetric nature of the Giardia trophozoite, this term is defined spatially as the trophozoite is viewed from the dorsal side, with the two nuclei dorsal to the ventral disc, and the ventral disc toward the anterior.		pr	2014-02-05T13:24:55Z					cellular_component											owl:Class	
GO:0036360	biolink:NamedThing	sorocarp stalk morphogenesis	The process in which the sorocarp stalk is generated and organized. The sorocarp stalk is a tubular structure that consists of cellulose-covered cells stacked on top of each other and surrounded by an acellular stalk tube composed of cellulose and glycoprotein. An example of this process is found in Dictyostelium discoideum.	tmpzr1t_l9r_go_relaxed.owl	fruiting body stalk morphogenesis							bf	2012-09-20T11:21:30Z					biological_process											owl:Class	
GO:0031288	biolink:NamedThing	sorocarp morphogenesis	The process in which the sorocarp is generated and organized. An example of this process is found in Dictyostelium discoideum.	tmpzr1t_l9r_go_relaxed.owl	fruiting body morphogenesis													biological_process											owl:Class	
GO:0001761	biolink:NamedThing	beta-alanine transmembrane transporter activity	Enables the transfer of beta-alanine from one side of a membrane to the other. Beta-alanine is 3-aminopropanoic acid.	tmpzr1t_l9r_go_relaxed.owl	beta-alanine transporter activity													molecular_function											owl:Class	
GO:0032640	biolink:NamedThing	tumor necrosis factor production	The appearance of tumor necrosis factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Tumor necrosis factor is an inflammatory cytokine produced by macrophages/monocytes during acute inflammation and which is responsible for a diverse range of signaling events within cells, leading to necrosis or apoptosis.	tmpzr1t_l9r_go_relaxed.owl	tumor necrosis factor biosynthetic process|tumor necrosis factor biosynthesis|TNF-alpha biosynthetic process|TNF alpha biosynthesis|TNF-alpha biosynthesis|tumor necrosis factor anabolism|tumor necrosis factor secretion|tumor necrosis factor formation|Tnfa production|tumor necrosis factor-alpha production|tumor necrosis factor synthesis|TNF production|TNF biosynthesis|TNF biosynthetic process|TNF-alpha production|cachectin production					Note that this term refers only to the specific, original 'tumor necrosis factor' protein (TNF) and not other members of the tumor necrosis factor superfamily (those with the gene symbol root 'TNFSF'). That this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.		sl	2015-06-15T22:59:26Z			GO:1990774|GO:0042533		biological_process											owl:Class	
GO:0098558	biolink:NamedThing	lumenal side of smooth endoplasmic reticulum membrane	The side (leaflet) of the smooth endoplasmic reticulum membrane that faces the lumen.	tmpzr1t_l9r_go_relaxed.owl								dos	2013-12-03T12:19:28Z					cellular_component											owl:Class	
GO:0030241	biolink:NamedThing	skeletal muscle myosin thick filament assembly	The aggregation, arrangement and bonding together of proteins to form the myosin-based thick filaments of myofibrils in skeletal muscle.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0007351	biolink:NamedThing	tripartite regional subdivision	Subdivision of the embryo along the anterior/posterior axis into anterior, posterior and terminal regions.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0036332	biolink:NamedThing	placental growth factor-activated receptor activity	Combining with placental growth factor (PlGF) and transmitting the signal across the plasma membrane to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	PlGF receptor activity|PlGF-activated receptor activity|placental growth factor receptor activity							bf	2012-09-05T09:34:37Z					molecular_function											owl:Class	
GO:0036323	biolink:NamedThing	vascular endothelial growth factor receptor-1 signaling pathway	Any series of molecular signals initiated by the binding of an extracellular ligand to a vascular endothelial growth factor receptor-1 (VEGFR-1) located on the surface of the receiving cell, and ending with regulation of a downstream cellular process, e.g. transcription.	tmpzr1t_l9r_go_relaxed.owl	VEGFR-1 signaling pathway|FLT1 signaling pathway|VEGFR1 signaling pathway							bf	2012-09-04T15:11:21Z					biological_process											owl:Class	
GO:0004697	biolink:NamedThing	protein kinase C activity	Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein. This reaction requires diacylglycerol.	tmpzr1t_l9r_go_relaxed.owl	PKCdelta|PKC activity|PKC|nPKCtheta|PKCalpha|nPKC|nPKCdelta|ATP:protein phosphotransferase (diacylglycerol-dependent) activity|diacylglycerol-activated phospholipid-dependent protein kinase C activity|PKCgamma|PKCbeta|PKCzeta|STK24|nPKCepsilon|PKCepsilon|cPKCalpha|cPKC|diacylglycerol-activated phospholipid-dependent PKC activity|nPKCeta|protein kinase Cepsilon activity|cPKCbeta|cPKCgamma|Pkc1p				Reactome:R-HSA-1433508|Reactome:R-HSA-9010681|Reactome:R-HSA-5625784|Reactome:R-HSA-751040|Reactome:R-HSA-5671749|Reactome:R-HSA-927889|Reactome:R-HSA-5229194|Reactome:R-HSA-450533|EC:2.7.11.13|Reactome:R-HSA-9626817|Reactome:R-HSA-193703|Reactome:R-HSA-2730863|Reactome:R-HSA-74615|Reactome:R-HSA-5138432|Reactome:R-HSA-909552|Reactome:R-HSA-9021357|Reactome:R-HSA-8934446|Reactome:R-HSA-2179413|Reactome:R-HSA-429698|Reactome:R-HSA-5218823|Reactome:R-HSA-9632858|Reactome:R-HSA-450550|Reactome:R-HSA-198314|Reactome:R-HSA-374664|Reactome:R-HSA-5623667|MetaCyc:2.7.11.13-RXN|Reactome:R-HSA-5218805							GO:0004701		molecular_function											owl:Class	
GO:0061524	biolink:NamedThing	central canal development	The process whose specific outcome is the formation of the central canal of the spinal cord from its formation to the mature structure. The central canal is a spinal cord structure that is part of the ventricular system and is filled with cerebral-spinal fluid and runs the length of the spinal cord.	tmpzr1t_l9r_go_relaxed.owl								dph	2013-04-20T08:18:31Z					biological_process											owl:Class	
GO:1903823	biolink:NamedThing	telomere single strand break repair	Single strand break repair that takes place in a telomere.	tmpzr1t_l9r_go_relaxed.owl	telomeric single strand break repair|telomere SSBR|single strand break repair in telomere|telomere single-strand break repair							jl	2015-01-19T16:12:29Z					biological_process											owl:Class	
GO:0048160	biolink:NamedThing	primary follicle stage	The stage in oogenesis when a single layer of cuboidal follicle cells surrounds the oocyte. The oocyte nucleus is large.	tmpzr1t_l9r_go_relaxed.owl	mammalian oogenesis stage 3													biological_process											owl:Class	
GO:1902375	biolink:NamedThing	nuclear tRNA 3'-trailer cleavage, endonucleolytic	Any tRNA 3'-trailer cleavage, endonucleolytic that takes place in nucleus.	tmpzr1t_l9r_go_relaxed.owl	tRNA 3'-end cleavage, endonucleolytic in cell nucleus|endonucleolytic tRNA 3'-end cleavage in cell nucleus|tRNA 3'-end cleavage, endonucleolytic in nucleus|endonucleolytic tRNA 3'-trailer cleavage in cell nucleus|tRNA 3'-trailer cleavage, endonucleolytic in cell nucleus|endonucleolytic tRNA 3'-end cleavage in nucleus|endonucleolytic tRNA 3'-trailer cleavage in nucleus							al	2013-08-30T09:17:30Z					biological_process											owl:Class	
GO:0020031	biolink:NamedThing	polar ring of apical complex	An electron dense ring at the most anterior position of the apical complex, from which the conoid fibers originate; formed during an invasive life cycle stage of an apicomplexan parasite.	tmpzr1t_l9r_go_relaxed.owl	anterior polar ring of apical complex|upper polar ring of apical complex													cellular_component											owl:Class	
GO:0002044	biolink:NamedThing	blood vessel endothelial cell migration involved in intussusceptive angiogenesis	The orderly movement of endothelial cells into the extracellular matrix in order to form new blood vessels during intussusceptive angiogenesis.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0003091	biolink:NamedThing	renal water homeostasis	Renal process involved in the maintenance of an internal steady state of water in the body.	tmpzr1t_l9r_go_relaxed.owl	water homeostasis by the renal system													biological_process											owl:Class	
GO:0048258	biolink:NamedThing	3-ketoglucose-reductase activity	Catalysis of the reaction: NADP+ + 3-dehydro-alpha-D-glucose = NADPH + alpha-D-glucose.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:KETOGLUCOSE-REDUCTASE-RXN									molecular_function											owl:Class	
GO:0014729	biolink:NamedThing	regulation of the velocity of shortening of skeletal muscle modulating contraction	Any process that modulates velocity of shortening of a skeletal muscle contraction. The shortening leads to reduction of the length of muscle fibers and sarcomeres.	tmpzr1t_l9r_go_relaxed.owl	regulation of the velocity of shortening of skeletal muscle during contraction													biological_process											owl:Class	
GO:0002010	biolink:NamedThing	excitation of vasomotor center by baroreceptor signaling	The process in which the molecular signal from the arterial baroreceptors is relayed to the vasomotor center causing it to signal increase arterial pressure.	tmpzr1t_l9r_go_relaxed.owl	excitation of vasomotor center by baroreceptor signalling													biological_process											owl:Class	
GO:0072260	biolink:NamedThing	metanephric interstitial fibroblast fate commitment	The process in which the developmental fate of a cell becomes restricted such that it will develop into a metanephric interstitial fibroblast.	tmpzr1t_l9r_go_relaxed.owl	metanephros interstitial cell fate commitment							mah	2010-03-19T04:18:10Z					biological_process											owl:Class	
GO:0009947	biolink:NamedThing	centrolateral axis specification	The establishment, maintenance and elaboration of the centrolateral axis. In plants, this axis is duplicated and runs from the midrib to the margin of the leaf.	tmpzr1t_l9r_go_relaxed.owl	centrolateral axis determination|mediolateral axis specification													biological_process											owl:Class	
GO:0034188	biolink:NamedThing	apolipoprotein A-I receptor activity	Combining with apolipoprotein A-I and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0060342	biolink:NamedThing	photoreceptor inner segment membrane	The membrane surrounding the inner segment of a vertebrate photoreceptor. The photoreceptor inner segment contains mitochondria, ribosomes and membranes where opsin molecules are assembled and passed to be part of the outer segment discs.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0071916	biolink:NamedThing	dipeptide transmembrane transporter activity	Enables the transfer of a dipeptide from one side of a membrane to the other. A dipeptide is a combination of two amino acids linked together by a peptide (-CO-NH-) bond.	tmpzr1t_l9r_go_relaxed.owl	dipeptide transporter activity							mah	2010-09-24T10:32:36Z			GO:0042936		molecular_function											owl:Class	
GO:1902671	biolink:NamedThing	left anterior basal body	Any ciliary basal body that is part of a left anterior flagellum found in Giardia species (trophozoite stage).	tmpzr1t_l9r_go_relaxed.owl	left anterior flagellum ciliary basal body|cilium basal body of left anterior cilium|ciliary basal body of left anterior flagellum|cilial basal body of left anterior cilium|cilium basal body of left anterior flagellum|cilial basal body of left anterior flagellum|microtubule basal body of left anterior cilium|ciliary basal body of left anterior cilium|microtubule basal body of left anterior flagellum					Note that we deem cilium and microtubule-based flagellum to be equivalent. Also note that, due to the asymmetric nature of the Giardia trophozoite, this term is defined spatially as the trophozoite is viewed from the dorsal side, with the two nuclei dorsal to the ventral disc, and the ventral disc toward the anterior.		pr	2014-02-05T14:28:44Z					cellular_component											owl:Class	
GO:0097554	biolink:NamedThing	left anterior flagellum	A cilium (also called flagellum) found in Giardia species (trophozoite stage). It originates at the left anterior basal body, extends laterally through the cytoplasm, crosses the right anterior axoneme, and exits as a membrane-bound flagellum on the anterior left side of the cell.	tmpzr1t_l9r_go_relaxed.owl	left anterior cilium					Note that we deem cilium and microtubule-based flagellum to be equivalent; the primary term name reflects frequency of use. Also note that, due to the asymmetric nature of the Giardia trophozoite, this term is defined spatially as the trophozoite is viewed from the dorsal side, with the two nuclei dorsal to the ventral disc, and the ventral disc toward the anterior.		pr	2014-02-05T12:47:41Z					cellular_component											owl:Class	
GO:0014035	biolink:NamedThing	neural crest cell fate determination	The process in which a cell becomes capable of differentiating autonomously into a neural crest cell regardless of its environment; upon determination, the cell fate cannot be reversed.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0035622	biolink:NamedThing	intrahepatic bile duct development	The progression of the intrahepatic bile ducts over time, from their formation to the mature structure. Intrahepatic bile ducts (bile ducts within the liver) collect bile from bile canaliculi in the liver, and connect to the extrahepatic bile ducts (bile ducts outside the liver).	tmpzr1t_l9r_go_relaxed.owl	intrahepatic biliary duct development|IHBD development							bf	2010-12-08T04:10:50Z					biological_process											owl:Class	
GO:1904158	biolink:NamedThing	axonemal central apparatus assembly	The aggregation, arrangement and bonding together of a set of components to form an axonemal central apparatus.	tmpzr1t_l9r_go_relaxed.owl	axonemal central apparatus formation							krc	2015-04-16T18:46:11Z					biological_process											owl:Class	
GO:0034749	biolink:NamedThing	Scrib-APC complex	A protein complex that contains the Scribble protein (a cell polarity determinant) and the tumor suppressor protein adenomatous polyposis coli (APC); may be involved in the control of cell proliferation.	tmpzr1t_l9r_go_relaxed.owl	hScrib-APC complex					Note that the gene/protein name 'APC' should not be confused with the abbreviation for 'anaphase promoting complex'.								cellular_component											owl:Class	
GO:0007495	biolink:NamedThing	visceral mesoderm-endoderm interaction involved in midgut development	The process of cell-cell signaling between visceral mesoderm cells and endoderm cells that is involved in the differentiation of cells in the midgut.	tmpzr1t_l9r_go_relaxed.owl	visceral mesoderm/endoderm interaction													biological_process											owl:Class	
GO:0050947	biolink:NamedThing	negative regulation of early stripe melanocyte differentiation	Any process that stops, prevents, or reduces the frequency, rate or extent of early stripe melanocyte differentiation.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of early stripe melanophore differentiation|down-regulation of early stripe melanocyte differentiation|inhibition of early stripe melanocyte differentiation|down regulation of early stripe melanocyte differentiation|downregulation of early stripe melanocyte differentiation													biological_process											owl:Class	
GO:0015437	biolink:NamedThing	lipopolysaccharide floppase activity	Enables the transfer of a lipopolysaccharide from the cytosolic to the exoplasmic leaftlet of a membrane, using energy from the hydrolysis of ATP.	tmpzr1t_l9r_go_relaxed.owl	lipopolysaccharide-transporting ATPase activity|ATPase-coupled intramembrane lipopolysaccharide transporter activity|ATP-dependent intramembrane lipopolysaccharide transporter activity|lipopolysaccharide floppase activity (cytosolic to exoplasmic leaftlet)|LPS-transporting ATPase activity													molecular_function											owl:Class	
GO:0061734	biolink:NamedThing	parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization	A positive regulation of the macromitophagy pathway that is triggered by mitochondrial depolarization and requires the function of a parkin-family molecule.	tmpzr1t_l9r_go_relaxed.owl	Park2-mediated stimulation of mitophagy in response to mitochondrial depolarization|PRKN-mediated stimulation of mitophagy in response to mitochondrial depolarization							dph	2015-09-14T13:48:57Z					biological_process											owl:Class	
GO:0061626	biolink:NamedThing	pharyngeal arch artery morphogenesis	The process in which the anatomical structures of a pharyngeal arch artery is generated and organized. The pharyngeal arch arteries are a series of six paired embryological vascular structures, the development of which give rise to several major arteries, such as the stapedial artery, the middle meningeal artery, the internal carotid artery and the pulmonary artery.	tmpzr1t_l9r_go_relaxed.owl	aortic arch artery morphogenesis							dph	2014-05-09T15:34:06Z					biological_process											owl:Class	
GO:1902772	biolink:NamedThing	positive regulation of phosphorelay signal transduction system involved in hydrogen peroxide mediated signaling pathway	Any positive regulation of phosphorelay signal transduction system that is involved in hydrogen peroxide mediated signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of two-component signal transduction involved in H2O2 mediated signaling pathway|stimulation of two-component signal transduction involved in hydrogen peroxide mediated signalling pathway|activation of two-component signal transduction involved in hydrogen peroxide mediated signaling pathway|up regulation of two-component signal transduction involved in hydrogen peroxide mediated signaling pathway|positive regulation of two-component signal transduction system (phosphorelay) involved in H2O2 mediated signaling pathway|up-regulation of two-component signal transduction involved in hydrogen peroxide mediated signaling pathway|positive regulation of histidyl-aspartyl phosphorelay involved in H2O2 mediated signaling pathway|positive regulation of two-component signal transduction system (phosphorelay) involved in hydrogen peroxide mediated signalling pathway|positive regulation of two-component signal transduction system (phosphorelay) involved in hydrogen peroxide mediated signaling pathway|positive regulation of phosphorelay signal transduction system involved in H2O2 mediated signaling pathway|activation of two-component signal transduction involved in hydrogen peroxide mediated signalling pathway|upregulation of two-component signal transduction involved in hydrogen peroxide mediated signaling pathway|stimulation of two-component signal transduction involved in H2O2 mediated signaling pathway|stimulation of two-component signal transduction involved in hydrogen peroxide mediated signaling pathway|up regulation of two-component signal transduction involved in H2O2 mediated signaling pathway|positive regulation of histidyl-aspartyl phosphorelay involved in hydrogen peroxide mediated signaling pathway|up-regulation of two-component signal transduction involved in hydrogen peroxide mediated signalling pathway|upregulation of two-component signal transduction involved in hydrogen peroxide mediated signalling pathway|positive regulation of phosphorelay signal transduction system involved in hydrogen peroxide mediated signalling pathway|activation of two-component signal transduction involved in H2O2 mediated signaling pathway|upregulation of two-component signal transduction involved in H2O2 mediated signaling pathway|positive regulation of histidyl-aspartyl phosphorelay involved in hydrogen peroxide mediated signalling pathway|up regulation of two-component signal transduction involved in hydrogen peroxide mediated signalling pathway							al	2014-03-17T11:42:08Z					biological_process											owl:Class	
GO:0072360	biolink:NamedThing	vascular cord development	The progression of the vascular cord over time from its initial formation until its mature state. The vascular cord is the primordial vasculature that will develop into blood vessels by the process of tubulogenesis.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-11-16T11:46:55Z					biological_process											owl:Class	
GO:0001874	biolink:NamedThing	(1->3)-beta-D-glucan immune receptor activity	Combining with (1->3)-beta-D-glucans to initiate an innate immune response.	tmpzr1t_l9r_go_relaxed.owl	1,3-beta-D-glucan receptor activity|beta-1,3-D-glucan receptor activity|(1->3)-beta-D-glucan receptor activity|zymosan receptor activity|(1,3)-beta-D-glucan receptor activity													molecular_function											owl:Class	
GO:0120121	biolink:NamedThing	tripartite attachment complex	A three-part cytoskeletal structure in kinetoplastid species linking mitochondrial DNA organised in a kinetoplast through the mitochondrial membranes to the basal body.	tmpzr1t_l9r_go_relaxed.owl	TAC							krc	2017-12-12T00:07:37Z					cellular_component											owl:Class	
GO:0071730	biolink:NamedThing	beak formation	The process that gives rise to the beak. This process pertains to the initial formation of a structure from unspecified parts. The avian beak is an external anatomical structure, in the head region, that is adapted for feeding self and young, catching prey, probing, etc. It encompasses, but is not restricted to, the maxilla, mandible, maxillary rhamphotheca, mandibular rhamphotheca, nostril, nasal fossa, nasal bones, egg tooth and rictus.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-03-17T03:57:07Z					biological_process											owl:Class	
GO:0044514	biolink:NamedThing	envenomation resulting in positive regulation of G protein-coupled receptor activity in other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant positive regulation of G protein-coupled receptor activity in of the bitten organism.	tmpzr1t_l9r_go_relaxed.owl	envenomation resulting in positive regulation of G-protein coupled receptor activity in other organism							jl	2012-02-26T11:06:15Z					biological_process											owl:Class	
GO:0000237	biolink:NamedThing	leptotene	The cell cycle phase which is the first stage of prophase I in meiosis, and during which the chromosomes first become visible.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Leptotene|Wikipedia:Meiosis#Leptotene	Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).								biological_process											owl:Class	
GO:0003193	biolink:NamedThing	pulmonary valve formation	The developmental process pertaining to the initial formation of the pulmonary valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-10-08T01:11:20Z					biological_process											owl:Class	
GO:0106125	biolink:NamedThing	reservosome matrix	A matrix composed of planar membranes, vesicles and lipid inclusions within the reservosome.	tmpzr1t_l9r_go_relaxed.owl								hjd	2018-05-03T18:00:03Z					cellular_component											owl:Class	
GO:0003060	biolink:NamedThing	negative regulation of the force of heart contraction by acetylcholine	The process in which acetylcholine released from vagus nerve endings binds to muscarinic receptors and decreases the force of heart muscle contraction.	tmpzr1t_l9r_go_relaxed.owl	decreased force of heart contraction by acetylcholine													biological_process											owl:Class	
GO:1905720	biolink:NamedThing	cytoplasmic microtubule bundle	Any microtubule bundle that is part of a cytoplasm.	tmpzr1t_l9r_go_relaxed.owl	microtubule fascicle of cytoplasm|microtubule bundle of cytoplasm							mah	2016-11-24T16:52:02Z					cellular_component											owl:Class	
GO:0034970	biolink:NamedThing	histone H3-R2 methylation	The modification of histone H3 by addition of a methyl group to arginine at position 2 of the histone.	tmpzr1t_l9r_go_relaxed.owl	histone lysine H3 R2 methylation|histone H3 R2 methylation|histone H3R2me													biological_process											owl:Class	
GO:0061447	biolink:NamedThing	endocardial cushion cell fate specification	The process involved in the specification of endocardial cushion cell identity. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment.	tmpzr1t_l9r_go_relaxed.owl								dph	2012-03-13T09:25:56Z					biological_process											owl:Class	
GO:0044471	biolink:NamedThing	envenomation resulting in pore formation in membrane of other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the aggregation, arrangement and bonding together of a set of components to form a pore complex in a membrane of the bitten organism.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-01-19T01:39:47Z					biological_process											owl:Class	
GO:0000475	biolink:NamedThing	maturation of 2S rRNA	Any process involved in the maturation of a precursor 2S ribosomal RNA (rRNA) molecule into a mature 2S rRNA molecule.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0021834	biolink:NamedThing	chemorepulsion involved in embryonic olfactory bulb interneuron precursor migration	The creation and reception of signals that guide olfactory bulb interneuron precursors down concentration gradients towards the olfactory bulb.	tmpzr1t_l9r_go_relaxed.owl	negative chemotaxis involved in embryonic olfactory bulb interneuron precursor migration													biological_process											owl:Class	
GO:0010521	biolink:NamedThing	telomerase inhibitor activity	Binds to and stops, prevents or reduces the activity of telomerase.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0003410	biolink:NamedThing	anterior rotation of the optic cup	A 90 degree-rotation of the optic cup resulting in its alignment with the anterior-posterior body axis.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-12-21T02:49:48Z					biological_process											owl:Class	
GO:0042421	biolink:NamedThing	norepinephrine biosynthetic process	The chemical reactions and pathways resulting in the formation of norepinephrine, a hormone secreted by the adrenal medulla, and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts in the central nervous system. It is also the demethylated biosynthetic precursor of epinephrine.	tmpzr1t_l9r_go_relaxed.owl	levarterenol biosynthesis|norepinephrine formation|levarterenol biosynthetic process|noradrenaline biosynthetic process|noradrenaline biosynthesis|norepinephrine synthesis|norepinephrine biosynthesis|norepinephrine anabolism													biological_process											owl:Class	
GO:0061144	biolink:NamedThing	alveolar secondary septum development	The progression of a secondary alveolar septum over time, from its formation to the mature structure. A secondary alveolar septum is a specialized epithelium that subdivides the initial saccule.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-05-25T10:43:55Z					biological_process											owl:Class	
GO:0070267	biolink:NamedThing	oncosis	A cellular process that results in swelling of the cell body, and that is morphologically characteristic of necrotic cell death.	tmpzr1t_l9r_go_relaxed.owl						Note that oncosis is sometimes described as a type of cell death, but recent nomenclature recommendations define it as a feature of necrotic cell death rather than a distinct mode of cell death.								biological_process											owl:Class	
GO:1990717	biolink:NamedThing	axonemal central bridge	Part of the 9+2 axoneme, that occurs in most motile cilia, consisting of the two bridges which connect the central pair of single microtubules.	tmpzr1t_l9r_go_relaxed.owl								krc	2015-03-27T22:38:31Z					cellular_component											owl:Class	
GO:0047520	biolink:NamedThing	11-cis-retinyl-palmitate hydrolase activity	Catalysis of the reaction: 11-cis-retinyl palmitate + H(2)O = 11-cis-retinol + H(+) + palmitate.	tmpzr1t_l9r_go_relaxed.owl	11-cis-retinyl-palmitate acylhydrolase activity|RPH|11-cis-retinol palmitate esterase activity				EC:3.1.1.63|KEGG_REACTION:R03049|Reactome:R-HSA-2465941|RHEA:19697|MetaCyc:11-CIS-RETINYL-PALMITATE-HYDROLASE-RXN									molecular_function											owl:Class	
GO:2000817	biolink:NamedThing	regulation of histone H3-T3 phosphorylation involved in chromosome passenger complex localization to kinetochore	Any regulation of histone H3-T3 phosphorylation that is involved in chromosome passenger complex localization to kinetochore.	tmpzr1t_l9r_go_relaxed.owl	regulation of histone H3-T3 phosphorylation involved in CPC complex localization to kinetochore|regulation of histone H3-T3 phosphorylation involved in CPC localization to kinetochore|regulation of histone H3-T3 phosphorylation involved in chromosome passenger complex localisation to kinetochore|regulation of histone H3-T3 phosphorylation involved in chromosomal passenger complex localization to kinetochore							mah	2011-07-12T11:37:40Z					biological_process											owl:Class	
GO:0034709	biolink:NamedThing	methylosome	A large (20 S) protein complex that possesses protein arginine methyltransferase activity and modifies specific arginines to dimethylarginines in the arginine- and glycine-rich domains of several spliceosomal Sm proteins, thereby targeting these proteins to the survival of motor neurons (SMN) complex for assembly into small nuclear ribonucleoprotein (snRNP) core particles. Proteins found in the methylosome include the methyltransferase JBP1 (PRMT5), pICln (CLNS1A), MEP50 (WDR77), and unmethylated forms of SM proteins that have RG domains.	tmpzr1t_l9r_go_relaxed.owl	20S methylosome|20S methyltransferase complex													cellular_component											owl:Class	
GO:0008158	biolink:NamedThing	hedgehog receptor activity	Combining with a member of the hedgehog protein family and transmitting the signal across the membrane to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	patched activity													molecular_function											owl:Class	
GO:0030599	biolink:NamedThing	pectinesterase activity	Catalysis of the reaction: pectin + n H2O = n methanol + pectate.	tmpzr1t_l9r_go_relaxed.owl	pectin pectylhydrolase activity|pectase activity|pectin demethoxylase activity|pectin methyl esterase activity|pectin methoxylase activity|pectinoesterase activity|pectin methylesterase activity				EC:3.1.1.11|MetaCyc:PECTINESTERASE-RXN|RHEA:22380									molecular_function											owl:Class	
GO:0021725	biolink:NamedThing	superior raphe nucleus development	The process whose specific outcome is the progression of the superior raphe nucleus over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl	anterior raphe nucleus development|superior central nucleus development													biological_process											owl:Class	
GO:0003326	biolink:NamedThing	pancreatic A cell fate commitment	The commitment of a cell to a pancreatic A cell and its capacity to differentiate into a pancreatic A cell. A pancreatic A cell is a cell in the pancreas that secretes glucagon.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-11-02T08:29:00Z					biological_process											owl:Class	
GO:0034508	biolink:NamedThing	centromere complex assembly	The aggregation, arrangement and bonding together of proteins and centromeric DNA molecules to form a centromeric protein-DNA complex. Includes the formation of the chromatin structures which form a platform for the kinetochore, and assembly of the kinetochore onto this specialized chromatin. In fission yeast and higher eukaryotes this process also includes the formation of heterochromatin at the outer repeat (pericentric) regions of the centromere.	tmpzr1t_l9r_go_relaxed.owl	chromosome, centromeric region assembly|centromere assembly|centromere organization													biological_process											owl:Class	
GO:0044626	biolink:NamedThing	envenomation resulting in positive regulation of cell migration in other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the positive regulation of cell migration in the bitten organism.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-07-04T05:08:21Z					biological_process											owl:Class	
GO:0090512	biolink:NamedThing	eisosome membrane domain/MCC	A plasma membrane part that is composed of a furrow-like plasma membrane domain and associated integral transmembrane proteins.	tmpzr1t_l9r_go_relaxed.owl								tb	2012-12-07T17:00:19Z					cellular_component											owl:Class	
GO:0032483	biolink:NamedThing	regulation of Rab protein signal transduction	Any process that modulates the frequency, rate or extent of Rab protein signal transduction.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0106232	biolink:NamedThing	hydroxyisourate hydrolase complex	A hydrolase complex that converts 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline. This is the second step of the three-step enzymatic reaction that degrades uric acid to (S)-allantoin.	tmpzr1t_l9r_go_relaxed.owl	HIU hydrolase complex|HIUH complex|5-hydroxyisourate hydrolase complex							hjd	2019-10-31T16:34:19Z					cellular_component											owl:Class	
GO:0001520	biolink:NamedThing	outer dense fiber	A supramolecular fiber found in the flagella of mammalian sperm that surrounds the nine microtubule doublets. These dense fibers are stiff and noncontractile. In human, they consist of about 10 major and at least 15 minor proteins, where all major proteins are ODF1, ODF2 or ODF2-related proteins.	tmpzr1t_l9r_go_relaxed.owl	outer dense fibre													cellular_component											owl:Class	
GO:0007381	biolink:NamedThing	specification of segmental identity, labial segment	The specification of the characteristic structures of the labial segment following establishment of segment boundaries. Identity is considered to be the aggregate of characteristics by which a structure is recognized.	tmpzr1t_l9r_go_relaxed.owl						See also the fly_anatomy.ontology term 'labial segment ; FBbt:00000014'.								biological_process											owl:Class	
GO:2000744	biolink:NamedThing	positive regulation of anterior head development	Any process that activates or increases the frequency, rate or extent of anterior head development.	tmpzr1t_l9r_go_relaxed.owl								yaf	2011-06-14T09:44:17Z					biological_process											owl:Class	
GO:0019902	biolink:NamedThing	phosphatase binding	Binding to a phosphatase.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1902577	biolink:NamedThing	protein localization to medial cortical node	A process in which a protein is transported to, or maintained in, a location within a medial cortical node.	tmpzr1t_l9r_go_relaxed.owl	protein localisation in medial cortical node|protein localization in medial cortical node|protein localisation to medial cortical node							mah	2013-12-17T14:09:28Z					biological_process											owl:Class	
GO:0036071	biolink:NamedThing	N-glycan fucosylation	The process of transferring a fucosyl group to an N-glycan. An N-glycan is the carbohydrate portion of an N-glycoprotein when attached to a nitrogen from asparagine or arginine side-chains.	tmpzr1t_l9r_go_relaxed.owl	glycoprotein fucosylation							bf	2011-12-15T04:54:24Z					biological_process											owl:Class	
GO:0021729	biolink:NamedThing	superior reticular formation development	The process whose specific outcome is the progression of the superior reticular formation over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0005769	biolink:NamedThing	early endosome	A membrane-bounded organelle that receives incoming material from primary endocytic vesicles that have been generated by clathrin-dependent and clathrin-independent endocytosis; vesicles fuse with the early endosome to deliver cargo for sorting into recycling or degradation pathways.	tmpzr1t_l9r_go_relaxed.owl					NIF_Subcellular:nlx_subcell_20090701									cellular_component											owl:Class	
GO:0061779	biolink:NamedThing	Tapasin-ERp57 complex	Subunit of the MHC class I peptide loading complex (GO:0042824) (=PLC) involved in the assembly of the heavy-chain-beta2-microglobulin dimers of the MHC class I molecules that fold with eight to ten residue peptides in the endoplasmic reticulum. Required for the inhibition of the reduction of the disulfide bonds of the heavy chains and the assembly and stabilization of the PLC, suggesting it may play a structural rather than a catalytic role.	tmpzr1t_l9r_go_relaxed.owl								dph	2016-08-05T12:12:08Z					cellular_component											owl:Class	
GO:0060481	biolink:NamedThing	lobar bronchus epithelium development	The biological process whose specific outcome is the progression of a lobar bronchus epithelium from an initial condition to its mature state. This process begins with the formation of the lobar bronchus epithelium and ends with the mature structure. The lobar bronchus epithelium is the tissue made up of epithelial cells that lines the inside of the lobar bronchus.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0048132	biolink:NamedThing	female germ-line stem cell asymmetric division	The self-renewing division of a germline stem cell in the female gonad, to produce a daughter stem cell and a daughter germ cell, which will divide to form the female gametes.	tmpzr1t_l9r_go_relaxed.owl	female germ-line stem cell renewal											GO:0048141		biological_process											owl:Class	
GO:0016183	biolink:NamedThing	synaptic vesicle coating	The formation of clathrin coated pits in the presynaptic membrane endocytic zone, triggered by the presence of high concentrations of synaptic vesicle components. This process leads to, but does not include budding of the membrane to form new vesicles.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0034535	biolink:NamedThing	1,2-dihydroxy-8-methylnaphthalene dioxygenase activity	Catalysis of the reaction: 1,2-dihydroxy-8-methylnaphthalene + O2 = 2-hydroxy-8-methylchromene-2-carboxylate + H+.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0781									molecular_function											owl:Class	
GO:0050161	biolink:NamedThing	succinyl-CoA:oxalate CoA-transferase	Catalysis of the reaction: oxalate + succinyl-CoA = oxalyl-CoA + succinate.	tmpzr1t_l9r_go_relaxed.owl	succinyl-beta-ketoacyl-CoA transferase activity|oxalate coenzyme A-transferase activity|oxalate CoA-transferase activity|succinyl-CoA:oxalate CoA-transferase activity				RHEA:23588|EC:2.8.3.2|MetaCyc:OXALATE-COA-TRANSFERASE-RXN|KEGG_REACTION:R01559									molecular_function											owl:Class	
GO:0080096	biolink:NamedThing	phosphatidate-sterol O-acyltransferase activity	Catalysis of the reaction: a phosphatidate + a sterol = a sterol ester + a lysophosphatidate.	tmpzr1t_l9r_go_relaxed.owl								dhl	2009-04-23T03:41:42Z					molecular_function											owl:Class	
GO:0090506	biolink:NamedThing	axillary shoot meristem initiation	A developmental process that results in the initiation of an axillary shoot meristem. An axillary shoot meristem is a shoot meristem formed in the axil of a leaf.	tmpzr1t_l9r_go_relaxed.owl	axillary bud meristem initiation							tb	2012-10-23T14:47:00Z					biological_process											owl:Class	
GO:0090383	biolink:NamedThing	phagosome acidification	Any process that reduces the pH of the phagosome, measured by the concentration of the hydrogen ion.	tmpzr1t_l9r_go_relaxed.owl	phagosomal acidification							tb	2010-10-27T10:20:22Z					biological_process											owl:Class	
GO:0047262	biolink:NamedThing	polygalacturonate 4-alpha-galacturonosyltransferase activity	Catalysis of the reaction: UDP-D-galacturonate + 1,4-alpha-D-galacturonosyl(n) = 1,4-alpha-D-galacturonosyl(n+1) + UDP.	tmpzr1t_l9r_go_relaxed.owl	UDP-D-galacturonate:1,4-alpha-poly-D-galacturonate 4-alpha-D-galacturonosyltransferase activity|uridine diphosphogalacturonate-polygalacturonate alpha-galacturonosyltransferase activity|UDP galacturonate-polygalacturonate alpha-galacturonosyltransferase activity				EC:2.4.1.43|RHEA:13573|MetaCyc:2.4.1.43-RXN							GO:0050375		molecular_function											owl:Class	
GO:0061579	biolink:NamedThing	N-acyl homoserine lactone synthase activity	Catalyzing the reaction: acyl-[acyl-carrier-protein] + S-adenosyl-L-methionine -> [acyl-carrier- protein] + S-methyl-5'-thioadenosine + N-acyl-L-homoserine lactone.	tmpzr1t_l9r_go_relaxed.owl	autoinducer-1 synthase				RHEA:10096|EC:2.3.1.184			dph	2013-11-15T19:48:23Z					molecular_function											owl:Class	
GO:0102760	biolink:NamedThing	6-deoxocathasterone hydroxylase activity	Catalysis of the reaction: 6-deoxycathasterone + O2 + a reduced electron acceptor <=> 6-deoxoteasterone + H2O + an oxidized electron acceptor.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-774									molecular_function											owl:Class	
GO:0031132	biolink:NamedThing	serine 3-dehydrogenase activity	Catalysis of the reaction: L-serine + NADP(+) = L-alpha-formylglycine + 2 H(+) + NADPH.	tmpzr1t_l9r_go_relaxed.owl	L-serine:NADP+ 3-oxidoreductase activity				Wikipedia:Serine_3-dehydrogenase|MetaCyc:RXN0-2201|EC:1.1.1.276|KEGG_REACTION:R06126|RHEA:21596									molecular_function											owl:Class	
GO:0010159	biolink:NamedThing	specification of animal organ position	The regionalization process in which information that determines the correct position at which animal organ primordia are formed is generated and perceived resulting in correct positioning of the new animal organ.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0102880	biolink:NamedThing	isobazzanene synthase activity	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate <=> isobazzanene + diphosphoric acid.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-8419									molecular_function											owl:Class	
GO:0033940	biolink:NamedThing	glucuronoarabinoxylan endo-1,4-beta-xylanase activity	Catalysis of the endohydrolysis of (1->4)-beta-D-xylosyl links in some glucuronoarabinoxylans.	tmpzr1t_l9r_go_relaxed.owl	glucuronoarabinoxylan 1,4-beta-D-xylanohydrolase activity|feraxan endoxylanase activity|glucuronoxylan xylanohydrolase activity|endoarabinoxylanase activity|glucuronoxylanase activity|glucuronoxylan xylohydrolase activity|feraxanase activity				MetaCyc:3.2.1.136-RXN|EC:3.2.1.136									molecular_function											owl:Class	
GO:0035078	biolink:NamedThing	induction of programmed cell death by ecdysone	Any process induced by the steroid hormone 20-hydroxyecdysone (ecdysone) that directly activates any of the steps required for programmed cell death.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0044586	biolink:NamedThing	cellotetraose binding	Binding to a cellotetraose, an oligosaccharide consisting of four glucose residues resulting from hydrolysis of cellulose.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-04-24T04:56:10Z					molecular_function											owl:Class	
GO:0036270	biolink:NamedThing	response to diuretic	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diuretic stimulus. A diuretic is an agent that promotes the excretion of urine through its effects on kidney function.	tmpzr1t_l9r_go_relaxed.owl						Note that this term is in the subset of terms that should not be used for direct manual annotation of gene products. It was created to be used for cross-referencing by other ontologies. Direct annotations to this term may be amended during annotation QC.		bf	2012-07-09T01:26:24Z					biological_process											owl:Class	
GO:0044605	biolink:NamedThing	phosphocholine transferase activity	Catalysis of the reaction: CDP-choline + protein-serine = CMP + protein-serine-choline phosphate.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-05-24T04:44:25Z					molecular_function											owl:Class	
GO:0140630	biolink:NamedThing	all-trans-phytoene synthase activity	Catalysis of the reaction: 2 geranylgeranyl diphosphate -> all-trans-phytoene + 2 diphosphate.	tmpzr1t_l9r_go_relaxed.owl	phytoene synthase activity	https://github.com/geneontology/go-ontology/issues/21165						pg	2021-03-25T18:04:01Z					molecular_function											owl:Class	
GO:0060209	biolink:NamedThing	estrus	The estrous cycle phase in which a female is sexually receptive.	tmpzr1t_l9r_go_relaxed.owl	oestrus					Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase. To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).								biological_process											owl:Class	
GO:0032182	biolink:NamedThing	ubiquitin-like protein binding	Binding to a small conjugating protein such as ubiquitin or a ubiquitin-like protein.	tmpzr1t_l9r_go_relaxed.owl	small conjugating protein binding													molecular_function											owl:Class	
GO:0050380	biolink:NamedThing	undecaprenyl-diphosphatase activity	Catalysis of the reaction:  di-trans,octa-cis-undecaprenyl diphosphate + H2O = di-trans,octa-cis-undecaprenyl phosphate + H+ + phosphate.	tmpzr1t_l9r_go_relaxed.owl	C55-isoprenyl diphosphatase activity|C(55)-isoprenyl pyrophosphatase activity|C(55)-isoprenyl diphosphatase activity|C55-isoprenyl pyrophosphatase activity|isoprenyl pyrophosphatase activity|undecaprenyl-diphosphate phosphohydrolase activity	https://github.com/geneontology/go-ontology/issues/21789			KEGG_REACTION:R05627|MetaCyc:UNDECAPRENYL-DIPHOSPHATASE-RXN|RHEA:28094|EC:3.6.1.27									molecular_function											owl:Class	
GO:0097449	biolink:NamedThing	astrocyte projection	A prolongation or process extending from the soma of an astrocyte and wrapping around neurons.	tmpzr1t_l9r_go_relaxed.owl	vellous process|peripheral astrocyte process|astrocyte process				NIF_Subcellular:sao1630537580			pr	2012-12-17T13:29:55Z					cellular_component											owl:Class	
GO:0097391	biolink:NamedThing	chemokine (C-X-C motif) ligand 13 production	The appearance of chemokine (C-X-C motif) ligand 13 (CXCL13) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	tmpzr1t_l9r_go_relaxed.owl	CXCL13 production							pr	2012-10-23T07:58:28Z					biological_process											owl:Class	
GO:0051697	biolink:NamedThing	protein delipidation	The breakage of covalent bonds to detach lipid groups from a protein.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0034794	biolink:NamedThing	cyclopropanecarboxyl-CoA decyclase activity	Catalysis of the reaction: cyclopropanecarboxyl-CoA = crotonoyl-CoA.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r1057|EC:5.5.1.-									molecular_function											owl:Class	
GO:1902791	biolink:NamedThing	undecan-2-one biosynthetic process	The chemical reactions and pathways resulting in the formation of undecan-2-one.	tmpzr1t_l9r_go_relaxed.owl	undecan-2-one anabolism|undecan-2-one biosynthesis|undecan-2-one formation|undecan-2-one synthesis							tt	2014-03-22T02:13:07Z					biological_process											owl:Class	
GO:0008261	biolink:NamedThing	allatostatin receptor activity	Combining with allatostatin to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1902378	biolink:NamedThing	VEGF-activated neuropilin signaling pathway involved in axon guidance	Any VEGF-activated neuropilin signaling pathway that is involved in axon guidance.	tmpzr1t_l9r_go_relaxed.owl	VEGF-Npn-1 signaling involved in axon guidance|VEGF-activated neuropilin signaling pathway involved in axon pathfinding|VEGF-Npn-1 signaling involved in axon pathfinding|vascular endothelial growth factor-activated neuropilin signaling pathway involved in axon guidance|vascular endothelial growth factor-activated neuropilin signaling pathway involved in axon growth cone guidance|VEGF-activated neuropilin signaling pathway involved in axon chemotaxis|vascular endothelial growth factor-activated neuropilin signaling pathway involved in axon chemotaxis|vascular endothelial growth factor-activated neuropilin signaling pathway involved in axon pathfinding|VEGF-Npn-1 signaling involved in axon growth cone guidance|VEGF-activated neuropilin signaling pathway involved in axon growth cone guidance|VEGF-Npn-1 signaling involved in axon chemotaxis							bf	2013-09-02T13:44:13Z					biological_process											owl:Class	
GO:0033912	biolink:NamedThing	2,6-beta-fructan 6-levanbiohydrolase activity	Catalysis of the hydrolysis of (2->6)-beta-D-fructofuranan, to remove successive disaccharide residues as levanbiose, i.e. 6-(beta-D-fructofuranosyl)-D-fructose, from the end of the chain.	tmpzr1t_l9r_go_relaxed.owl	2,6-beta-D-fructofuranan 6-(beta-D-fructosyl)-D-fructose-hydrolase activity|beta-2,6-fructan-6-levanbiohydrolase activity|2,6-beta-D-fructan 6-beta-D-fructofuranosylfructohydrolase activity|2,6-beta-D-fructan 6-levanbiohydrolase activity|levanbiose-producing levanase activity				MetaCyc:3.2.1.64-RXN|EC:3.2.1.64									molecular_function											owl:Class	
GO:1901906	biolink:NamedThing	diadenosine pentaphosphate metabolic process	The chemical reactions and pathways involving diadenosine pentaphosphate.	tmpzr1t_l9r_go_relaxed.owl	diadenosine pentaphosphate metabolism|diadenosyl pentaphosphate metabolism|diadenosyl pentaphosphate metabolic process							al	2013-02-13T13:48:16Z					biological_process											owl:Class	
GO:0097143	biolink:NamedThing	PUMA-BCL-xl complex	A heterodimeric protein complex consisting of PUMA and BCL-xl, members of the Bcl-2 family of anti- and proapoptotic regulators.	tmpzr1t_l9r_go_relaxed.owl								pr	2011-08-02T01:44:10Z					cellular_component											owl:Class	
GO:0005714	biolink:NamedThing	early recombination nodule	An electron dense structure that is associated with meiotic chromosomes in leptotene or zygotene during meiosis I.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0032050	biolink:NamedThing	clathrin heavy chain binding	Binding to a clathrin heavy chain.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0031681	biolink:NamedThing	G-protein beta-subunit binding	Binding to a G-protein beta subunit.	tmpzr1t_l9r_go_relaxed.owl	G-beta protein subunit binding													molecular_function											owl:Class	
GO:0090511	biolink:NamedThing	periclinal cell division	A cell division process where the division plane is parallel to the surface of the organ. It creates a new cell layer or cell file.	tmpzr1t_l9r_go_relaxed.owl								tb	2012-11-21T11:52:40Z					biological_process											owl:Class	
GO:0030620	biolink:NamedThing	U2 snRNA binding	Binding to a U2 small nuclear RNA (U2 snRNA).	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0007429	biolink:NamedThing	secondary branching, open tracheal system	Sprouting of secondary branches in an open tracheal system. These form from the tips of primary branches and are formed by individual cells that roll up into unicellular tubes. An example of this is found in Drosophila melanogaster.	tmpzr1t_l9r_go_relaxed.owl	secondary tracheal branching													biological_process											owl:Class	
GO:0099057	biolink:NamedThing	integral component of presynaptic endocytic zone membrane	The component of the presynaptic endocytic zone membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:1990597	biolink:NamedThing	AIP1-IRE1 complex	A protein complex consisting of IRE1 (inositol-requiring enzyme-1) bound to AIP1 (ASK1-interacting protein 1/DAB2-interacting protein).	tmpzr1t_l9r_go_relaxed.owl	IRE1-DAB2IP complex|AIP1-ERN1 complex|IRE1alpha-AIP1 complex							bf	2015-01-05T15:14:35Z					cellular_component											owl:Class	
GO:0102998	biolink:NamedThing	4-sulfomuconolactone hydrolase activity	Catalysis of the reaction: (5-oxo-2-sulfonato-2,5-dihydrofuran-2-yl)acetate + H2O <=> maleylacetate + sulfite + 2 H+.	tmpzr1t_l9r_go_relaxed.owl					EC:3.1.1.92|RHEA:33711|MetaCyc:RXN-9733									molecular_function											owl:Class	
GO:0035401	biolink:NamedThing	histone kinase activity (H3-Y41 specific)	Catalysis of the transfer of a phosphate group to the tyrosine-41 residue of histone H3.	tmpzr1t_l9r_go_relaxed.owl	histone tyrosine kinase activity (H3-Y41 specific)|histone-tyrosine kinase activity (H3-Y41 specific)							bf	2010-03-24T10:01:14Z					molecular_function											owl:Class	
GO:0005173	biolink:NamedThing	stem cell factor receptor binding	Binding to a stem cell factor receptor (SCFR), a type III transmembrane kinase receptor.	tmpzr1t_l9r_go_relaxed.owl	stem cell factor|KIT binding|SCF|SCFR binding|stem cell factor receptor ligand													molecular_function											owl:Class	
GO:0034864	biolink:NamedThing	2,4,4-trimethylpentanal dehydrogenase activity	Catalysis of the reaction: 2,4,4-trimethylpentanal + H2O = 2,4,4-trimethylpentanoate + 3 H+ + 2 e-.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r1275									molecular_function											owl:Class	
GO:0010130	biolink:NamedThing	anaerobic ethylbenzene catabolic process	The chemical reactions and pathways resulting in the breakdown of ethylbenzene, a benzene derivative with an ethyl group attached to the ring, which occurs in the absence of oxygen.	tmpzr1t_l9r_go_relaxed.owl	anaerobic ethylbenzene degradation|anaerobic ethylbenzene catabolism|anaerobic ethylbenzene breakdown				MetaCyc:PWY-481									biological_process											owl:Class	
GO:0018913	biolink:NamedThing	anaerobic ethylbenzene metabolic process	The chemical reactions and pathways involving ethylbenzene (phenylethane), a benzene derivative with an ethyl group attached to the ring, that occur in the absence of oxygen.	tmpzr1t_l9r_go_relaxed.owl	anaerobic ethylbenzene metabolism				UM-BBD_pathwayID:ethb									biological_process											owl:Class	
GO:0033998	biolink:NamedThing	inulin fructotransferase (DFA-III-forming) activity	Catalysis of the reaction: [(2->1)-beta-D-fructosyl](n) = [(2->1)-beta-D-fructosyl](n-1) + alpha-D-fructofuranose beta-D-fructofuranose 1,2':2,3'-dianhydride. This reaction is the production of alpha-D-fructofuranose beta-D-fructofuranose 1,2':2,3'-dianhydride (DFA III) by successively eliminating the diminishing (2->1)-beta-D-fructan (inulin) chain from the terminal D-fructosyl-D-fructosyl disaccharide.	tmpzr1t_l9r_go_relaxed.owl	inulinase II activity|inulin D-fructosyl-D-fructosyltransferase (1,2':2,3'-dianhydride-forming) activity|inulin D-fructosyl-D-fructosyltransferase (forming alpha-D-fructofuranose beta-D-fructofuranose 1,2':2,3'-dianhydride) activity|inulin fructotransferase (depolymerizing) activity|inulase II activity|inulin fructotransferase (depolymerizing, difructofuranose-1,2':2,3'-dianhydride-forming) activity|2,1-beta-D-fructan lyase (alpha-D-fructofuranose-beta-D-fructofuranose-1,2':2,3'-dianhydride-forming) activity|inulin fructotransferase (DFA-III-producing) activity				EC:4.2.2.18|MetaCyc:4.2.2.18-RXN									molecular_function											owl:Class	
GO:0047450	biolink:NamedThing	crotonoyl-[acyl-carrier-protein] hydratase activity	Catalysis of the reaction: (3R)-3-hydroxybutanoyl-[acyl-carrier protein] = H2O + but-2-enoyl-[acyl-carrier protein].	tmpzr1t_l9r_go_relaxed.owl	(3R)-3-hydroxybutanoyl-acyl-carrier-protein hydro-lyase (but-2-enoyl-acyl-carrier protein-forming)|crotonoyl-ACP hydratase activity|(3R)-3-hydroxybutanoyl-[acyl-carrier-protein] hydro-lyase activity|enoyl acyl carrier protein hydrase activity|3-hydroxybutyryl acyl carrier protein dehydratase activity|crotonyl acyl carrier protein hydratase activity|(3R)-3-hydroxybutanoyl-acyl-carrier-protein hydro-lyase activity|beta-hydroxybutyryl acyl carrier protein dehydrase activity|crotonoyl-[acyl-carrier protein] hydratase activity|crotonoyl-acyl-carrier-protein hydratase activity|beta-hydroxybutyryl acyl carrier protein (ACP) dehydrase activity				KEGG_REACTION:R04428|EC:4.2.1.58|MetaCyc:4.2.1.58-RXN							GO:0080063		molecular_function											owl:Class	
GO:1990068	biolink:NamedThing	seed dehydration	The seed development process whose outcome is the drying of a maturing seed.	tmpzr1t_l9r_go_relaxed.owl								tb	2013-03-27T21:16:03Z					biological_process											owl:Class	
GO:1901629	biolink:NamedThing	regulation of presynaptic membrane organization	Any process that modulates the frequency, rate or extent of presynaptic membrane organization.	tmpzr1t_l9r_go_relaxed.owl	regulation of pre-synaptic membrane organization|regulation of presynaptic membrane organisation							ans	2012-11-15T11:40:32Z					biological_process											owl:Class	
GO:0097248	biolink:NamedThing	maintenance of protein location in cell cortex of cell tip	A process in which a protein or protein complex is maintained in a specific location in the cell cortex of a cell tip, and is prevented from moving elsewhere. The cell cortex of a cell tip is the region directly beneath the plasma membrane at either end of the longest axis of a cylindrical or elongated cell.	tmpzr1t_l9r_go_relaxed.owl								pr	2012-02-20T04:27:31Z					biological_process											owl:Class	
GO:0031868	biolink:NamedThing	prostaglandin F2-alpha receptor binding	Binding to a prostaglandin F2-alpha receptor.	tmpzr1t_l9r_go_relaxed.owl	prostaglandin F2-alpha receptor ligand|prostanoid FP receptor binding													molecular_function											owl:Class	
GO:0004579	biolink:NamedThing	dolichyl-diphosphooligosaccharide-protein glycotransferase activity	Catalysis of the reaction: dolichyl diphosphooligosaccharide + protein L-asparagine = dolichyl diphosphate + a glycoprotein with the oligosaccharide chain attached by glycosylamine linkage to protein L-asparagine.	tmpzr1t_l9r_go_relaxed.owl	dolichyldiphosphoryloligosaccharide-protein oligosaccharyltransferase activity|dolichyldiphosphooligosaccharide-protein glycosyltransferase activity|dolichyl-diphosphooligosaccharide:protein-L-asparagine oligopolysaccharidotransferase activity|oligomannosyltransferase activity|dolichylpyrophosphodiacetylchitobiose-protein glycosyltransferase activity|asparagine N-glycosyltransferase activity|dolichyl-diphosphooligosaccharide-protein glycosyltransferase activity|dolichyldiphosphooligosaccharide-protein oligosaccharyltransferase activity				Reactome:R-HSA-9694793|Reactome:R-HSA-446209|RHEA:22980|MetaCyc:2.4.1.119-RXN|EC:2.4.99.18									molecular_function											owl:Class	
GO:0004576	biolink:NamedThing	oligosaccharyl transferase activity	Catalysis of the transfer of a oligosaccharyl group to an acceptor molecule, typically another carbohydrate or a lipid.	tmpzr1t_l9r_go_relaxed.owl	oligosaccharide transferase activity													molecular_function											owl:Class	
GO:0102336	biolink:NamedThing	3-oxo-arachidoyl-CoA synthase activity	Catalysis of the reaction: stearoyl-CoA(4-) + malonyl-CoA(5-) + H+ <=> 3-oxoicosanoyl-CoA. + carbon dioxide + coenzyme A.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-13294|RHEA:35319									molecular_function											owl:Class	
GO:0039501	biolink:NamedThing	suppression by virus of host type I interferon production	Any viral process that results in the inhibition of host cell type I interferon production. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families.	tmpzr1t_l9r_go_relaxed.owl	suppression by virus of host type I IFN production|suppression by virus of host interferon type I production|negative regulation by virus of host type I interferon production				VZ:875			bf	2011-05-11T03:53:20Z					biological_process											owl:Class	
GO:0018487	biolink:NamedThing	vanillate O-demethylase (anaerobic) activity	Catalysis of the reaction: vanillate + Co+ = Co3+-CH3 + 3,4-dihydroxybenzoate.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0758									molecular_function											owl:Class	
GO:0032136	biolink:NamedThing	adenine/cytosine mispair binding	Binding to a double-stranded DNA region containing an A/C mispair.	tmpzr1t_l9r_go_relaxed.owl	A/C mispair binding|C/A mispair binding|cytosine/adenine mispair binding													molecular_function											owl:Class	
GO:0032978	biolink:NamedThing	protein insertion into membrane from inner side	The process in which a protein is incorporated into a lipid bilayer, e.g., the prokaryotic, mitochondrial, or chloroplast inner membrane, from the inner side.	tmpzr1t_l9r_go_relaxed.owl	insertion of proteins into membrane from the inner side													biological_process											owl:Class	
GO:0044647	biolink:NamedThing	host-symbiont bicellular tight junction	An occluding cell-cell junction formed between the membranes of the apical end of an invading cell (e.g. a merozoite in Plasmodium) and a host target cell (e.g. erythrocyte for Plasmodium infection). The junction is a stable yet dynamic structure that moves around the symbiont cell during invasion, enclosing it in a vacuole surrounded by a membrane.	tmpzr1t_l9r_go_relaxed.owl	host-parasite tight junction|host-pathogen tight junction							jl	2012-07-11T12:56:18Z					cellular_component											owl:Class	
GO:0102155	biolink:NamedThing	S-sulfolactate dehydrogenase activity	Catalysis of the reaction: (S)-3-sulfonatolactate + NAD <=> 3-sulfonatopyruvate(2-) + NADH + H+.	tmpzr1t_l9r_go_relaxed.owl					RHEA:28194|EC:1.1.1.310|MetaCyc:RXN-11689									molecular_function											owl:Class	
GO:0000838	biolink:NamedThing	Hrd1p ubiquitin ligase ERAD-M complex	A multiprotein complex that recognizes and ubiquitinates proteins with misfolded membrane domains during ER-associated protein degradation (ERAD). In S. cerevisiae, this complex contains the ubiquitin ligase Hrd1p.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0071762	biolink:NamedThing	heavy chain immunoglobulin complex	A protein complex composed of two identical immunoglobulin heavy chains of the IgNAR isotype held together by disulfide bonds and lacking immunoglobulin light chains.	tmpzr1t_l9r_go_relaxed.owl	IgNAR immunoglobulin complex|HCab|Ig NAR immunoglobulin complex|IgNAR antibody					Note that a heavy chain immunoglobulin complex has the function of antigen binding if a suitable antigen is available. Note that IgNAR is found in serum of cartilaginous fish as a heavy chain dimer without immunoglobulin light chains. Note that HCab is found in camels as a heavy chain dimer without immunoglobulin light chains.		mah	2010-03-24T01:44:53Z					cellular_component											owl:Class	
GO:0052622	biolink:NamedThing	ATP dimethylallyltransferase activity	Catalysis of the reaction: delta(2)-isopentenyl diphosphate + ATP = diphosphate + N6-(delta(2)-isopentenyl)adenosine 5'-triphosphate.	tmpzr1t_l9r_go_relaxed.owl	ATP isopentenyltransferase activity|dimethylallyl-diphosphate:ATP dimethylallyltransferase activity|2-isopentenyl-diphosphate:ATP 2-isopentenyltransferase activity|2-isopentenyl-diphosphate:ATP delta2-isopentenyltransferase activity				EC:2.5.1.-|MetaCyc:RXN-4303|KEGG_REACTION:R08052			ai	2010-08-26T10:45:38Z					molecular_function											owl:Class	
GO:0005150	biolink:NamedThing	interleukin-1, type I receptor binding	Binding to a Type I interleukin-1 receptor.	tmpzr1t_l9r_go_relaxed.owl	interleukin-1, type I receptor ligand|IL-1 type I													molecular_function											owl:Class	
GO:0070097	biolink:NamedThing	delta-catenin binding	Binding to the delta subunit of the catenin complex.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0030280	biolink:NamedThing	structural constituent of skin epidermis	The action of a molecule that contributes to the structural integrity of an epidermal cutaneous structure.	tmpzr1t_l9r_go_relaxed.owl	structural constituent of epidermis													molecular_function											owl:Class	
GO:1990753	biolink:NamedThing	equatorial cell cortex	The region of the cell cortex in a mitotically dividing cell that flanks the central spindle and corresponds to the site of actomyosin ring formation that results in cleavage furrow formation and ingression.	tmpzr1t_l9r_go_relaxed.owl								kmv	2015-05-27T19:12:41Z					cellular_component											owl:Class	
GO:0047036	biolink:NamedThing	codeinone reductase (NADPH) activity	Catalysis of the reaction: codeine + NADP(+) = codeinone + H(+) + NADPH.	tmpzr1t_l9r_go_relaxed.owl	codeine:NADP+ oxidoreductase activity				RHEA:19209|KEGG_REACTION:R05124|MetaCyc:1.1.1.247-RXN|EC:1.1.1.247									molecular_function											owl:Class	
GO:0000484	biolink:NamedThing	cleavage between SSU-rRNA and 5.8S rRNA of tetracistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, 2S rRNA, LSU-rRNA)	Endonucleolytic cleavage between the SSU-rRNA and the 5.8S rRNA of an rRNA molecule originally produced as a tetracistronic rRNA transcript that contained the Small SubUnit (SSU) rRNA, the 5.8S rRNA, 2S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0018856	biolink:NamedThing	benzoyl acetate-CoA ligase activity	Catalysis of the reaction: 3-oxo-3-phenylpropionate + CoA + ATP = AMP + diphosphate + benzoyl acetyl-CoA.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0242|SABIO-RK:5058|KEGG_REACTION:R05452									molecular_function											owl:Class	
GO:0047303	biolink:NamedThing	glycine-oxaloacetate transaminase activity	Catalysis of the reaction: glycine + oxaloacetate = L-aspartate + glyoxylate.	tmpzr1t_l9r_go_relaxed.owl	glycine-oxaloacetate aminotransferase activity|glycine-oxalacetate aminotransferase activity|glycine--oxaloacetate aminotransferase activity|glycine:oxaloacetate aminotransferase activity				MetaCyc:2.6.1.35-RXN|KEGG_REACTION:R00373|EC:2.6.1.35|RHEA:17141									molecular_function											owl:Class	
GO:0102063	biolink:NamedThing	beta-curcumene synthase activity	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate(3-) <=> diphosphoric acid + (-)-beta-curcumene.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-10598									molecular_function											owl:Class	
GO:0004492	biolink:NamedThing	methylmalonyl-CoA decarboxylase activity	Catalysis of the reaction: (S)-2-methyl-3-oxopropanoyl-CoA = propanoyl-CoA + CO2.	tmpzr1t_l9r_go_relaxed.owl	methylmalonyl-coenzyme A decarboxylase activity|(S)-2-methyl-3-oxopropanoyl-CoA carboxy-lyase activity|(S)-methylmalonyl-CoA carboxy-lyase (propanoyl-CoA-forming)|(S)-methylmalonyl-CoA carboxy-lyase activity				EC:7.2.4.3|MetaCyc:METHYLMALONYL-COA-DECARBOXYLASE-RXN|RHEA:21396									molecular_function											owl:Class	
GO:0102272	biolink:NamedThing	homophytochelatin synthase activity (polymer-forming)	Catalysis of the reaction: glutathionate + a poly gamma-glutamylcysteine-beta-alanine = glycine + a poly gamma-glutamylcysteine-beta-alanine.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-12528									molecular_function											owl:Class	
GO:0019155	biolink:NamedThing	3-(imidazol-5-yl)lactate dehydrogenase activity	Catalysis of the reaction: (S)-3-(imidazol-5-yl)lactate + NADP+ = 3-(imidazol-5-yl)pyruvate + NADPH + H+.	tmpzr1t_l9r_go_relaxed.owl	(S)-3-(imidazol-5-yl)lactate:NAD(P)+ oxidoreductase activity|imidazol-5-yl lactate dehydrogenase activity				MetaCyc:IMILACTDEHYDROG-RXN|EC:1.1.1.111									molecular_function											owl:Class	
GO:0062124	biolink:NamedThing	4-hydroxybutyrate receptor activity	Combining with 4-hydroxybutyrte to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	gamma-hydroxybutyrate receptor activity							dph	2019-05-15T12:22:38Z					molecular_function											owl:Class	
GO:0010438	biolink:NamedThing	cellular response to sulfur starvation	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of sulfur.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0032545	biolink:NamedThing	CURI complex	A protein complex that is involved in the transcription of ribosomal genes. In Saccharomyces this complex consists of Ckb2p, Utp22p, Rrp7p and Ifh1p.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0000092	biolink:NamedThing	mitotic anaphase B	The cell cycle phase during which the polar microtubules elongate and the two poles of the spindle move farther apart as part of mitosis.	tmpzr1t_l9r_go_relaxed.owl						Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).								biological_process											owl:Class	
GO:0043717	biolink:NamedThing	2-hydroxyglutaryl-CoA dehydratase activity	Catalysis of the reaction: (R)-2-hydroxyglutaryl-CoA = H2O + glutaconyl-CoA.	tmpzr1t_l9r_go_relaxed.owl	(R)-2-hydroxyglutaryl-CoA dehydratase activity				MetaCyc:RXN-1083|RHEA:42448									molecular_function											owl:Class	
GO:0033906	biolink:NamedThing	hyaluronoglucuronidase activity	Catalysis of the random hydrolysis of 1,3-linkages between beta-D-glucuronate and N-acetyl-D-glucosamine residues in hyaluronate.	tmpzr1t_l9r_go_relaxed.owl	hyaluronidase activity|orgelase activity|glucuronoglucosaminoglycan hyaluronate lyase activity|hyaluronate 3-glycanohydrolase activity				MetaCyc:3.2.1.36-RXN|EC:3.2.1.36									molecular_function											owl:Class	
GO:1905599	biolink:NamedThing	positive regulation of low-density lipoprotein receptor activity	Any process that activates or increases the frequency, rate or extent of low-density lipoprotein receptor activity.	tmpzr1t_l9r_go_relaxed.owl	up regulation of LDL receptor|up regulation of low-density lipoprotein receptor activity|upregulation of LDL receptor|up-regulation of LDL receptor|up regulation of LDLR activity|positive regulation of LDLR activity|activation of LDLR activity|activation of low-density lipoprotein receptor activity|activation of LDL receptor|up-regulation of low-density lipoprotein receptor activity|upregulation of LDLR activity|positive regulation of LDL receptor|up-regulation of LDLR activity|upregulation of low-density lipoprotein receptor activity							nc	2016-10-26T11:53:41Z					biological_process											owl:Class	
GO:0033984	biolink:NamedThing	indole-3-glycerol-phosphate lyase activity	Catalysis of the reaction: (1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate = indole + D-glyceraldehyde 3-phosphate.	tmpzr1t_l9r_go_relaxed.owl	indole synthase activity|tryptophan synthase alpha subunit activity|IGL|indoleglycerolphosphate aldolase activity|(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate D-glyceraldehyde-3-phosphate-lyase activity|BX1|indole-3-glycerolphosphate D-glyceraldehyde-3-phosphate-lyase activity|indole glycerol phosphate hydrolase activity|(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate D-glyceraldehyde-3-phosphate-lyase (indole-forming) activity|tryptophan synthase alpha activity|indole-3-glycerol phosphate lyase activity|TSA				MetaCyc:RXN0-2381|RHEA:14081|MetaCyc:4.1.2.8-RXN|KEGG_REACTION:R02340|EC:4.1.2.8									molecular_function											owl:Class	
GO:0097323	biolink:NamedThing	B cell adhesion	The attachment of a B cell to another cell via adhesion molecules.	tmpzr1t_l9r_go_relaxed.owl								pr	2012-06-06T01:59:19Z					biological_process											owl:Class	
GO:0047111	biolink:NamedThing	formate dehydrogenase (cytochrome-c-553) activity	Catalysis of the reaction: ferricytochrome C-553 + formate = ferrocytochrome C-553 + CO2.	tmpzr1t_l9r_go_relaxed.owl	formate dehydrogenase (cytochrome c-553)|formate:ferricytochrome-c-553 oxidoreductase activity				MetaCyc:1.2.2.3-RXN|EC:1.17.2.3|RHEA:15189									molecular_function											owl:Class	
GO:0019174	biolink:NamedThing	tetrahydrothiophene 1-oxide reductase activity	Catalysis of the reaction: tetrahydrothiophene 1-oxide + reduced acceptor = tetrahydrothiophene + acceptor.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:THTOREDUCT-RXN									molecular_function											owl:Class	
GO:0003411	biolink:NamedThing	cell motility involved in camera-type eye morphogenesis	Any process involved in the controlled self-propelled movement of a cell that results in translocation of the cell from one place to another and contributes to the physical shaping or formation of the camera-type eye.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-12-21T03:04:27Z					biological_process											owl:Class	
GO:1903040	biolink:NamedThing	exon-exon junction complex assembly	The aggregation, arrangement and bonding together of a set of components to form an exon-exon junction complex.	tmpzr1t_l9r_go_relaxed.owl	EJC assembly|EJC formation|exon-exon junction complex formation							sart	2014-05-20T14:52:07Z					biological_process											owl:Class	
GO:0042568	biolink:NamedThing	insulin-like growth factor binary complex	A complex of two proteins, which in animals is 50kDa and consists of the insulin-like growth factor (IGF) and one of the insulin-like growth factor binding protein-1 (IGFBP-1), -2 (IGFBP-2), -4 (IGFBP-4) and -6 (IGFBP-6). The complex plays a role in growth and development.	tmpzr1t_l9r_go_relaxed.owl	IGF binary complex													cellular_component											owl:Class	
GO:0120067	biolink:NamedThing	pyloric sphincter smooth muscle contraction	A process in which force is generated within gastric smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the narrowest part of the pylorus that separates the stomach from the duodenum.	tmpzr1t_l9r_go_relaxed.owl								krc	2017-06-13T22:38:26Z					biological_process											owl:Class	
GO:0102449	biolink:NamedThing	kaempferol 3-O-methyltransferase activity	Catalysis of the reaction: kaempferol oxoanion + S-adenosyl-L-methionine  <=> 3-O-methylkaempferol + S-adenosyl-L-homocysteine.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-13935									molecular_function											owl:Class	
GO:0044305	biolink:NamedThing	calyx of Held	The terminal specialization of a calyciferous axon which forms large synapses in the mammalian auditory central nervous system.	tmpzr1t_l9r_go_relaxed.owl					NIF_Subcellular:sao1684283879			jl	2010-02-05T02:33:20Z					cellular_component											owl:Class	
GO:1903951	biolink:NamedThing	positive regulation of AV node cell action potential	Any process that activates or increases the frequency, rate or extent of AV node cell action potential.	tmpzr1t_l9r_go_relaxed.owl	activation of AV node cardiac muscle cell action potential|activation of AV node cell action potential|upregulation of AV node cell action potential|activation of atrioventricular node cardiac muscle cell action potential|up-regulation of AV node cardiac muscle cell action potential|up regulation of AV node cardiac muscle cell action potential|positive regulation of atrioventricular node cardiac muscle cell action potential|up regulation of atrioventricular node cardiac muscle cell action potential|up-regulation of AV node cell action potential|upregulation of atrioventricular node cardiac muscle cell action potential|up-regulation of atrioventricular node cardiac muscle cell action potential|up regulation of AV node cell action potential|positive regulation of AV node cardiac muscle cell action potential|upregulation of AV node cardiac muscle cell action potential							nc	2015-02-20T14:59:50Z					biological_process											owl:Class	
GO:0099642	biolink:NamedThing	retrograde axonal protein transport	The directed movement of proteins along microtubules from the cell periphery toward the cell body in nerve cell axons.	tmpzr1t_l9r_go_relaxed.owl	retrograde axon cargo transport													biological_process											owl:Class	
GO:0047688	biolink:NamedThing	aspartate 4-decarboxylase activity	Catalysis of the reaction: L-aspartate = L-alanine + CO2.	tmpzr1t_l9r_go_relaxed.owl	L-aspartate 4-carboxy-lyase activity|aspartate omega-decarboxylase activity|L-aspartate 4-carboxy-lyase (L-alanine-forming)|aminomalonic decarboxylase activity|aspartate beta-decarboxylase activity|desulfinase activity|cysteine sulfinic desulfinase activity|L-cysteine sulfinate acid desulfinase activity|aspartic beta-decarboxylase activity|aspartic omega-decarboxylase activity|L-aspartate beta-decarboxylase activity				MetaCyc:ASPARTATE-4-DECARBOXYLASE-RXN|RHEA:12621|EC:4.1.1.12									molecular_function											owl:Class	
GO:0008744	biolink:NamedThing	L-xylulokinase activity	Catalysis of the reaction: ATP + L-xylulose = ADP + L-xylulose 5-phosphate.	tmpzr1t_l9r_go_relaxed.owl	L-xylulose kinase activity|ATP:L-xylulose 5-phosphotransferase activity|L-xylulokinase (phosphorylating)				EC:2.7.1.53|RHEA:18869|MetaCyc:LYXK-RXN									molecular_function											owl:Class	
GO:0008810	biolink:NamedThing	cellulase activity	Catalysis of the endohydrolysis of (1->4)-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans.	tmpzr1t_l9r_go_relaxed.owl	endoglucanase activity|celluase A|beta-1,4-glucanase activity|cellulase A 3|beta-1,4-endoglucan hydrolase activity|endoglucanase D|carboxymethyl cellulase activity|cellulosin AP|endo-1,4-beta-D-glucanohydrolase activity|endo-1,4-beta-D-glucanase activity|endo-1,4-beta-glucanase activity|alkali cellulase activity|9.5 cellulase activity|1,4-(1,3;1,4)-beta-D-glucan 4-glucanohydrolase activity|celludextrinase activity|avicelase activity|pancellase SS				MetaCyc:RXN-2043|EC:3.2.1.4									molecular_function											owl:Class	
GO:0004076	biolink:NamedThing	biotin synthase activity	Catalysis of the reaction: 2 S-adenosyl-L-methionine + dethiobiotin + S(2-) = 2 5'-deoxyadenosine + 2 L-methionine + biotin + H(+).	tmpzr1t_l9r_go_relaxed.owl	dethiobiotin:sulfur sulfurtransferase activity|biotin synthetase activity				EC:2.8.1.6|KEGG_REACTION:R01078|MetaCyc:2.8.1.6-RXN|RHEA:22060									molecular_function											owl:Class	
GO:0071104	biolink:NamedThing	response to interleukin-9	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-9 stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to IL-9							mah	2009-11-09T12:50:25Z					biological_process											owl:Class	
GO:0160005	biolink:NamedThing	PAT complex	A transmembrane protein complex located in the endoplasmic reticulum (ER) involved in the correct folding of multipass membrane proteins in the ER membrane after their release from the Sec61 translocon. In human, the substrate-binding Asterix (PAT10, WDR83OS) forms an obligate heterodimer with CCDC47.	tmpzr1t_l9r_go_relaxed.owl						PAT complex functions by shielding exposed hydrophilicity of transmembrane domains (TMDs) to prevent premature degradation and promote proper folding and bundling of TMDs.		rynl	2021-09-03T23:12:58Z					cellular_component											owl:Class	
GO:0018558	biolink:NamedThing	5,6-dihydroxy-3-methyl-2-oxo-1,2-dihydroquinoline dioxygenase activity	Catalysis of the reaction: 5,6-dihydroxy-3-methyl-2-oxo-1,2-dihydroquinoline + O2 = 3-methyl-5-hydroxy-6-(3-carboxy-3-oxopropenyl)-1H-2-pyridon.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0049|EC:1.13.11.-									molecular_function											owl:Class	
GO:0140696	biolink:NamedThing	(S)-2-hydroxyglutarate dehydrogenase activity	Catalysis of the reaction: (S)-2-hydroxyglutarate + a quinone = 2-oxoglutarate + a quinol.	tmpzr1t_l9r_go_relaxed.owl	L-2-hydroxyglutarate dehydrogenase activity	https://github.com/geneontology/go-ontology/issues/21957			RHEA:58664|EC:1.1.5.13			pg	2021-08-11T14:16:32Z					molecular_function											owl:Class	
GO:0102837	biolink:NamedThing	1-18:2-2-16:1-monogalactosyldiacylglycerol desaturase activity	Catalysis of the reaction: 1-18:2-2-16:1-monogalactosyldiacylglycerol + O2 + a reduced electron acceptor <=> 1-18:3-2-16:1-monogalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-8297|EC:1.14.19.35									molecular_function											owl:Class	
GO:0018545	biolink:NamedThing	NAD(P)H nitroreductase activity	Catalysis of the conversion of a nitrate group to an amino or hydroxylamino group on toluene or a toluene derivative.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_enzymeID:e0346									molecular_function											owl:Class	
GO:0034200	biolink:NamedThing	D,D-heptose 1,7-bisphosphate phosphatase activity	Catalysis of the reaction: D-beta-D-heptose 1,7-bisphosphate + H2O = D-beta-D-heptose 1-phosphate + phosphate.	tmpzr1t_l9r_go_relaxed.owl					RHEA:28518|MetaCyc:RXN0-4361									molecular_function											owl:Class	
GO:0036445	biolink:NamedThing	neuronal stem cell division	The self-renewing division of a neuronal stem cell.	tmpzr1t_l9r_go_relaxed.owl	NSC division							bf	2013-10-30T10:03:27Z					biological_process											owl:Class	
GO:0004411	biolink:NamedThing	homogentisate 1,2-dioxygenase activity	Catalysis of the reaction: homogentisate + O(2) = 4-maleylacetoacetate + H(+).	tmpzr1t_l9r_go_relaxed.owl	homogentisate oxygenase activity|homogentisate dioxygenase activity|homogentisic acid oxygenase activity|homogentisate:oxygen 1,2-oxidoreductase (decyclizing)|homogentisic acid oxidase activity|homogentisate oxidase activity|homogentisicase activity|homogentisic oxygenase activity				RHEA:15449|MetaCyc:HOMOGENTISATE-12-DIOXYGENASE-RXN|Reactome:R-HSA-71164|KEGG_REACTION:R02519|EC:1.13.11.5|UM-BBD_reactionID:r0105									molecular_function											owl:Class	
GO:0004501	biolink:NamedThing	ecdysone 20-monooxygenase activity	Catalysis of the reaction: AH(2) + Ecdysone + O(2) = 20-hydroxyecdysone + A + H(2)O.	tmpzr1t_l9r_go_relaxed.owl	ecdysone 20-hydroxylase activity|ecdysone,hydrogen-donor:oxygen oxidoreductase (20-hydroxylating)|ecdysone modification|alpha-ecdysone C-20 hydroxylase activity				EC:1.14.99.22|KEGG_REACTION:R02374|RHEA:14021|MetaCyc:ECDYSONE-20-MONOOXYGENASE-RXN									molecular_function											owl:Class	
GO:0018559	biolink:NamedThing	1,1-dichloro-2-(dihydroxy-4-chlorophenyl)-(4-chlorophenyl)ethene 1,2-dioxygenase activity	Catalysis of the reaction: 1,1-dichloro-2-(dihydroxy-4'-chorophenyl)-2-(4-chlorophenyl)ethene + O2 = 6-oxo-2-hydroxy-7-(4-chlorophenyl)-3,8,8-trichloroocta-2E,4E,7-trienoate.	tmpzr1t_l9r_go_relaxed.owl	1,1-dichloro-2-(dihydroxy-4-chlorophenyl)-(4-chlorophenyl)ethylene 1,2-dioxygenase activity				UM-BBD_reactionID:r0442|EC:1.13.11.-									molecular_function											owl:Class	
GO:0070653	biolink:NamedThing	high-density lipoprotein particle receptor binding	Binding to a high-density lipoprotein receptor.	tmpzr1t_l9r_go_relaxed.owl	high-density lipoprotein receptor binding|HDL receptor binding							mah	2009-05-28T03:44:33Z					molecular_function											owl:Class	
GO:0009040	biolink:NamedThing	ureidoglycolate dehydrogenase activity	Catalysis of the reaction: (S)-ureidoglycolate + NAD(P)+ = oxalureate + NAD(P)H + H+.	tmpzr1t_l9r_go_relaxed.owl	(S)-ureidoglycolate:NAD(P)+ oxidoreductase activity				EC:1.1.1.154|MetaCyc:R165-RXN									molecular_function											owl:Class	
GO:0062121	biolink:NamedThing	linear element maturation	The meiotic cell cycle chromosome organization process in which LinE complexes closely associate with chromatin during meiotic prophase to form mature linear elements.	tmpzr1t_l9r_go_relaxed.owl	LinE focus formation|LinE chromosome loading							dph	2019-03-19T14:19:27Z					biological_process											owl:Class	
GO:0098788	biolink:NamedThing	dendritic knob	The terminal swelling of an apical dendrite of a ciliated olfactory receptor neuron. Each knob gives rise to 5 to 20 long delicate nonmotile cilia, which extend into the mucus covering the sensory epithelium.	tmpzr1t_l9r_go_relaxed.owl	apical dendritic knob													cellular_component											owl:Class	
GO:0005047	biolink:NamedThing	signal recognition particle binding	Binding to a signal recognition particle.	tmpzr1t_l9r_go_relaxed.owl	signal recognition particle receptor|docking protein					See also the cellular component term 'signal recognition particle, endoplasmic reticulum targeting ; GO:0005786'.								molecular_function											owl:Class	
GO:0090447	biolink:NamedThing	glycerol-3-phosphate 2-O-acyltransferase activity	Catalysis of the reaction: an acyl-CoA + sn-glycerol 3-phosphate = CoA + a 2-acyl-sn-glycerol 3-phosphate.	tmpzr1t_l9r_go_relaxed.owl								tb	2012-08-31T09:23:12Z					molecular_function											owl:Class	
GO:0047515	biolink:NamedThing	1,3-beta-oligoglucan phosphorylase activity	Catalysis of the reaction: [oligomeric (1->3)-beta-D-glucosyl](n) + phosphate = [(1->3)-beta-D-glucosyl](n-1) + alpha-D-glucose 1-phosphate.	tmpzr1t_l9r_go_relaxed.owl	1,3-beta-D-oligoglucan:phosphate alpha-D-glucosyltransferase activity|beta-1,3-oligoglucan:orthophosphate glucosyltransferase II activity|beta-1,3-oligoglucan phosphorylase activity				MetaCyc:13-BETA-OLIGOGLUCAN-PHOSPHORYLASE-RXN|EC:2.4.1.30|RHEA:16041									molecular_function											owl:Class	
GO:0099053	biolink:NamedThing	activating signal cointegrator 1 complex	A protein complex that contains TRIP4 (ASC1) and acts a transcriptional coactivator by interacting with transcription factors such as NF-kappa B.  In humans this complex has 4 subunits: TRIP4 + ASCC1-3.	tmpzr1t_l9r_go_relaxed.owl	ASC-1 complex													cellular_component											owl:Class	
GO:0103068	biolink:NamedThing	leukotriene C4 gamma-glutamyl transferase activity	Catalysis of the reaction: leukotriene C4 + a standard alpha amino acid = leukotriene D4 + an (gamma-L-glutamyl)-L-amino acid.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN66-336|EC:2.3.2.2									molecular_function											owl:Class	
GO:0090473	biolink:NamedThing	lys-arg specific dibasic protein processing	Any protein processing achieved by the cleavage of a peptide bond after a lysine-arginine amino acid residue combination within a protein.	tmpzr1t_l9r_go_relaxed.owl								tb	2012-10-01T10:42:30Z					biological_process											owl:Class	
GO:0090409	biolink:NamedThing	malonyl-CoA synthetase activity	Catalysis of the reaction: malonate + ATP + coenzyme A = malonyl-CoA + AMP + diphosphate.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-12359|RHEA:32139|EC:6.2.1.n3			tb	2011-06-10T01:51:16Z					molecular_function											owl:Class	
GO:0120299	biolink:NamedThing	peptide histaminyltransferase activity	Catalysis of the reaction: histamine + L-glutaminyl-[protein] = 5-histaminyl-L-glutamyl-[protein].	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/20685			RHEA:66564			krc	2021-01-19T03:23:48Z					molecular_function											owl:Class	
GO:0009660	biolink:NamedThing	amyloplast organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an amyloplast. An amyloplast is a plastid whose main function is to synthesize and store starch.	tmpzr1t_l9r_go_relaxed.owl	amyloplast organisation|amyloplast organization and biogenesis													biological_process											owl:Class	
GO:0050200	biolink:NamedThing	plasmalogen synthase activity	Catalysis of the reaction: acyl-CoA + 1-O-alk-1-enyl-glycero-3-phosphocholine = CoA + plasmenylcholine.	tmpzr1t_l9r_go_relaxed.owl	acyl-CoA:1-O-alk-1-enyl-glycero-3-phosphocholine 2-O-acyltransferase activity|lysoplasmenylcholine acyltransferase activity|O-1-alkenylglycero-3-phosphorylcholine acyltransferase activity|1-alkenyl-glycero-3-phosphorylcholine:acyl-CoA acyltransferase activity				EC:2.3.1.25|MetaCyc:PLASMALOGEN-SYNTHASE-RXN									molecular_function											owl:Class	
GO:0102953	biolink:NamedThing	hypoglycin A gamma-glutamyl transpeptidase activity	Catalysis of the reaction: glutathionate + hypoglycin A = L-cysteinylglycine + hypoglycin B.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-9157|EC:2.3.2.2									molecular_function											owl:Class	
GO:0060184	biolink:NamedThing	cell cycle switching	The process in which a cell switches cell cycle mode.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0008281	biolink:NamedThing	sulfonylurea receptor activity	Combining with sulfonylurea, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	sulphonylurea receptor activity					Note that this term represents an activity and not a gene product. Consider also annotating to the molecular function term 'potassium channel activity ; GO:0005267'.								molecular_function											owl:Class	
GO:0050122	biolink:NamedThing	N-acylhexosamine oxidase activity	Catalysis of the reaction: N-acetyl-D-glucosamine + H(2)O + O(2) = N-acetyl-D-glucosaminate + H(2)O(2) + H(+).	tmpzr1t_l9r_go_relaxed.owl	N-acyl-D-hexosamine oxidase activity|N-acyl-D-hexosamine:oxygen 1-oxidoreductase activity|N-acyl-beta-D-hexosamine:oxygen 1-oxidoreductase activity				KEGG_REACTION:R01203|RHEA:13029|EC:1.1.3.29|MetaCyc:N-ACYLHEXOSAMINE-OXIDASE-RXN									molecular_function											owl:Class	
GO:0031994	biolink:NamedThing	insulin-like growth factor I binding	Binding to insulin-like growth factor I.	tmpzr1t_l9r_go_relaxed.owl	IGF-I binding													molecular_function											owl:Class	
GO:0061837	biolink:NamedThing	neuropeptide processing	Any protein maturation process achieved by the cleavage of a peptide bond or bonds within a neuropeptide precursor. Processing leads to the attainment of the full functional capacity of the neuropeptide.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1900080	biolink:NamedThing	positive regulation of arginine biosynthetic process	Any process that activates or increases the frequency, rate or extent of arginine biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	upregulation of arginine formation|activation of arginine formation|activation of arginine biosynthetic process|up-regulation of arginine anabolism|upregulation of arginine biosynthesis|upregulation of arginine synthesis|activation of arginine anabolism|up regulation of arginine biosynthesis|up-regulation of arginine synthesis|up regulation of arginine anabolism|up regulation of arginine synthesis|up-regulation of arginine biosynthesis|positive regulation of arginine formation|positive regulation of arginine anabolism|positive regulation of arginine biosynthesis|positive regulation of arginine synthesis|activation of arginine biosynthesis|up regulation of arginine formation|up regulation of arginine biosynthetic process|activation of arginine synthesis|upregulation of arginine anabolism|upregulation of arginine biosynthetic process|up-regulation of arginine biosynthetic process|up-regulation of arginine formation							pr	2012-02-01T03:57:41Z					biological_process											owl:Class	
GO:0042656	biolink:NamedThing	JUN kinase kinase kinase kinase activity	Catalysis of the phosphorylation and activation of JUN kinase kinase kinases (JNKKKs).	tmpzr1t_l9r_go_relaxed.owl	JUNKKKK activity													molecular_function											owl:Class	
GO:0043877	biolink:NamedThing	galactosamine-6-phosphate isomerase activity	Catalysis of the reaction: D-galactosamine 6-phosphate + H2O = D-tagatose 6-phosphate + NH3.	tmpzr1t_l9r_go_relaxed.owl	AgaI|galactosamine-6-phosphate deaminase activity					This function is part of the pathway of N-acetyl-galactosamine and galactosamine utilization.								molecular_function											owl:Class	
GO:0005846	biolink:NamedThing	nuclear cap binding complex	A conserved heterodimeric protein complex that binds to the 5' terminal cap structure m7G(5')ppp(5')N of nascent eukaryotic RNA polymerase II transcripts such as pre-mRNA and U snRNA. The consists of proteins known as CBP20 and CBP80, binds to cap structures in the nucleus, and is involved in pre-mRNA splicing, 3'-end formation, and RNA nuclear export.	tmpzr1t_l9r_go_relaxed.owl	NCBP-NIP1 complex|snRNA cap binding complex|mRNA cap binding complex|CBC					Note that this complex can be found in the cytoplasm as well as the nucleus.								cellular_component											owl:Class	
GO:0102418	biolink:NamedThing	luteolin-7-O-glucoside 1,6-glucosyltransferase activity	Catalysis of the reaction: luteolin 7-O-beta-D-glucoside + UDP-alpha-D-glucose = luteolin-7-O-gentiobioside + UDP + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-13801									molecular_function											owl:Class	
GO:0045523	biolink:NamedThing	interleukin-27 receptor binding	Binding to an interleukin-27 receptor.	tmpzr1t_l9r_go_relaxed.owl	IL-27|interleukin-27 receptor ligand													molecular_function											owl:Class	
GO:0019154	biolink:NamedThing	glycolate dehydrogenase activity	Catalysis of the reaction: A + glycolate = AH(2) + glyoxylate.	tmpzr1t_l9r_go_relaxed.owl	glycolic acid dehydrogenase activity|glycolate:acceptor 2-oxidoreductase activity|glycolate:(acceptor) 2-oxidoreductase activity|glycolate oxidoreductase activity				KEGG_REACTION:R00476|MetaCyc:GLYCOLATEDEHYDRO-RXN|RHEA:21264|EC:1.1.99.14									molecular_function											owl:Class	
GO:0120148	biolink:NamedThing	host cell centrosome	A structure in a host cell comprised of a core structure (in most organisms, a pair of centrioles) and peripheral material from which a microtubule-based structure, such as a spindle apparatus, is organized. Centrosomes occur close to the nucleus during interphase in many eukaryotic cells, though in animal cells it changes continually during the cell-division cycle.	tmpzr1t_l9r_go_relaxed.owl	host centrosome							krc	2018-04-13T15:22:54Z					cellular_component											owl:Class	
GO:0044163	biolink:NamedThing	host cytoskeleton	Any of the various filamentous elements that form the internal framework of host cells, and typically remain after treatment of the cells with mild detergent to remove membrane constituents and soluble components of the host cytoplasm. The term embraces intermediate filaments, microfilaments, microtubules, the microtrabecular lattice, and other structures characterized by a polymeric filamentous nature and long-range order within the host cell. The various elements of the host cytoskeleton not only serve in the maintenance of host cellular shape but also have roles in other host cellular functions, including cellular movement, cell division, endocytosis, and movement of organelles.	tmpzr1t_l9r_go_relaxed.owl								jl	2009-08-11T04:27:04Z					cellular_component											owl:Class	
GO:0050623	biolink:NamedThing	berberine reductase activity	Catalysis of the reaction: (R)-canadine + 2 NADP(+) = berberine + H(+) + 2 NADPH.	tmpzr1t_l9r_go_relaxed.owl	(R)-tetrahydroberberine:NADP+ oxidoreductase activity|(R)-canadine synthase activity				EC:1.5.1.31|KEGG_REACTION:R07169|RHEA:21268|MetaCyc:1.5.1.31-RXN									molecular_function											owl:Class	
GO:0000344	biolink:NamedThing	plastid-encoded plastid RNA polymerase complex B	A plastid-encoded DNA-directed RNA polymerase complex that resembles eubacterial multisubunit RNA polymerases with a core composed of alpha, beta, and beta-prime subunits. An additional subunit, a sigma factor, is required for promoter recognition. PEP-B is distinguished from PEP-A by its sensitivity to the antibiotic rifampicin. PEP-B is found in both etioplasts and chloroplasts, but is the predominate form in etioplasts. It forms the core of the PEP-A form; the conversion from PEP-B to PEP-A occurs during chloroplast maturation.	tmpzr1t_l9r_go_relaxed.owl	PEP-B													cellular_component											owl:Class	
GO:0035318	biolink:NamedThing	imaginal disc-derived wing hair outgrowth	Extrusion of a cellular projection from the apical membrane of an epithelial cell in an imaginal disc-derived wing. Outgrowth initiates approximately 35 hours after puparium formation from the distal side of the cell, and at this stage the cellular extension is termed a prehair.	tmpzr1t_l9r_go_relaxed.owl	wing hair outgrowth|wing prehair outgrowth													biological_process											owl:Class	
GO:0098594	biolink:NamedThing	mucin granule	A secretory granule that contains mucin.	tmpzr1t_l9r_go_relaxed.owl								dos	2014-03-11T15:59:11Z					cellular_component											owl:Class	
GO:1903609	biolink:NamedThing	negative regulation of inward rectifier potassium channel activity	Any process that stops, prevents or reduces the frequency, rate or extent of inward rectifier potassium channel activity.	tmpzr1t_l9r_go_relaxed.owl	downregulation of Kir channel activity|down regulation of Kir channel activity|down-regulation of inward rectifier potassium channel activity|inhibition of inward rectifier potassium channel activity|downregulation of inward rectifier potassium channel activity|down regulation of inward rectifier potassium channel activity|inhibition of Kir channel activity|down-regulation of Kir channel activity|negative regulation of Kir channel activity							rl	2014-11-14T20:29:14Z					biological_process											owl:Class	
GO:0021745	biolink:NamedThing	nucleus ambiguus development	The process whose specific outcome is the progression of the nucleus ambiguus over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0008902	biolink:NamedThing	hydroxymethylpyrimidine kinase activity	Catalysis of the reaction: 4-amino-5-hydroxymethyl-2-methylpyrimidine + ATP = 4-amino-2-methyl-5-phosphomethylpyrimidine + ADP + 2 H(+).	tmpzr1t_l9r_go_relaxed.owl	hydroxymethylpyrimidine kinase (phosphorylating)|ATP:4-amino-5-hydroxymethyl-2-methylpyrimidine 5-phosphotransferase activity				RHEA:23096|MetaCyc:OHMETPYRKIN-RXN|EC:2.7.1.49|KEGG_REACTION:R03471									molecular_function											owl:Class	
GO:0061966	biolink:NamedThing	establishment of left/right asymmetry	The initial formation of the type asymmetry in an organism's body plan or part of an organism with respect to the left and right halves.	tmpzr1t_l9r_go_relaxed.owl								dph	2018-02-12T16:27:20Z					biological_process											owl:Class	
GO:0050372	biolink:NamedThing	ubiquitin-calmodulin ligase activity	Catalysis of the reaction: n ATP + calmodulin + n ubiquitin = n AMP + n diphosphate + ubiquitin(n)-calmodulin.	tmpzr1t_l9r_go_relaxed.owl	calmodulin:ubiquitin ligase (AMP-forming)|ubiquityl-calmodulin synthase activity|ubiquitin-calmodulin synthetase activity|uCaM-synthetase activity|ubiquityl-calmodulin synthetase activity				MetaCyc:UBIQUITIN--CALMODULIN-LIGASE-RXN									molecular_function											owl:Class	
GO:1902899	biolink:NamedThing	fatty acid methyl ester biosynthetic process	The chemical reactions and pathways resulting in the formation of fatty acid methyl ester.	tmpzr1t_l9r_go_relaxed.owl	fatty acid methyl ester anabolism|fatty acid methyl ester biosynthesis|fatty acid methyl ester formation|FAME biosynthetic process|fatty acid methyl ester synthesis							tt	2014-04-11T03:08:40Z					biological_process											owl:Class	
GO:0120112	biolink:NamedThing	UDP-glucose transmembrane transport into endoplasmic reticulum	The directed movement of UDP-glucose from cytosol to endoplasmic reticulum.	tmpzr1t_l9r_go_relaxed.owl								krc	2017-11-02T15:56:51Z					biological_process											owl:Class	
GO:0031484	biolink:NamedThing	myosin XIV complex	A myosin complex containing a class XIV myosin heavy chain and associated light chains; myosin XIV heavy chains are the simplest known, containing a motor domain, no classic IQ motif and variable length tails.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0051520	biolink:NamedThing	termination of bipolar cell growth	Any process that stops the active process of bipolar cell growth, polarized growth from both ends of a cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0070222	biolink:NamedThing	sulfide oxidation, using sulfide dehydrogenase	A sulfide oxidation process that proceeds via the reaction catalyzed by sulfide dehydrogenase.	tmpzr1t_l9r_go_relaxed.owl	sulphide oxidation, using sulfide dehydrogenase				MetaCyc:PWY-5274									biological_process											owl:Class	
GO:0102748	biolink:NamedThing	geranylgeranyl-chlorophyll a reductase activity	Catalysis of the reaction: H+ + geranylgeranyl-chlorophyll a + NADPH = dihydrogeranylgeranyl-chlorophyll a + NADP.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-7664									molecular_function											owl:Class	
GO:0047256	biolink:NamedThing	lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity	Catalysis of the reaction: cytolipin-H + UDP-N-acetyl-D-glucosamine = N-acetyl-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide + UDP.	tmpzr1t_l9r_go_relaxed.owl	UDP-N-acetyl-D-glucosamine:D-galactosyl-1,4-beta-D-glucosylceramide beta-1,3-acetylglucosaminyltransferase activity|beta1->3-N-acetylglucosaminyltransferase activity|uridine diphosphoacetylglucosamine-lactosylceramide beta-acetylglucosaminyltransferase activity|lactosylceramide beta-acetylglucosaminyltransferase activity|LA2 synthase activity				EC:2.4.1.206|MetaCyc:2.4.1.206-RXN|RHEA:13905									molecular_function											owl:Class	
GO:0050566	biolink:NamedThing	asparaginyl-tRNA synthase (glutamine-hydrolyzing) activity	Catalysis of the reaction: L-glutamine + aspartyl-tRNA(Asn) + ATP = L-glutamate + asparaginyl-tRNA(Asn) + phosphate + ADP.	tmpzr1t_l9r_go_relaxed.owl	Asp-tRNA(Asn) amidotransferase activity|Asp-tRNAAsn:L-glutamine amido-ligase (ADP-forming)|aspartyl-tRNAAsn amidotransferase activity|aspartyl-tRNAAsn:L-glutamine amido-ligase (ADP-forming)|aspartyl-tRNA(Asn) amidotransferase activity|Asp-AdT activity|asparaginyl-tRNA synthase (glutamine-hydrolysing)|Asp-tRNAAsn amidotransferase activity				MetaCyc:6.3.5.6-RXN|RHEA:14513|Wikipedia:Asparaginyl-tRNA_synthase_(glutamine-hydrolysing)|EC:6.3.5.6									molecular_function											owl:Class	
GO:0102648	biolink:NamedThing	D-ribose 5-phosphate:D-fructose 6-phosphate transaldolase activity	Catalysis of the reaction: D-fructose 6-phosphate + D-ribose 5-phosphate <=> D-glycero-D-altro-octulose 8-phosphate + D-glyceraldehyde 3-phosphate.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-15790									molecular_function											owl:Class	
GO:0043622	biolink:NamedThing	cortical microtubule organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of structures formed of microtubules and associated proteins in the cell cortex, i.e. just beneath the plasma membrane of a cell.	tmpzr1t_l9r_go_relaxed.owl	cortical microtubule cytoskeleton organization|cortical microtubule organization and biogenesis|cortical microtubule organisation													biological_process											owl:Class	
GO:0047349	biolink:NamedThing	D-ribitol-5-phosphate cytidylyltransferase activity	Catalysis of the reaction: D-ribitol 5-phosphate + CTP = CDP-ribitol + diphosphate.	tmpzr1t_l9r_go_relaxed.owl	cytidine diphosphoribitol pyrophosphorylase activity|ribitol 5-phosphate cytidylyltransferase activity|CDP-ribitol diphosphorylase activity|CDP-ribitol pyrophosphorylase activity|CDP ribitol pyrophosphorylase activity|cytidine diphosphate ribitol pyrophosphorylase activity|CTP:D-ribitol-5-phosphate cytidylyltransferase activity				EC:2.7.7.40|MetaCyc:2.7.7.40-RXN|KEGG_REACTION:R02921|RHEA:12456									molecular_function											owl:Class	
GO:0046281	biolink:NamedThing	cinnamic acid catabolic process	The chemical reactions and pathways resulting in the breakdown of cinnamic acid, 3-phenyl-2-propenoic acid.	tmpzr1t_l9r_go_relaxed.owl	cinnamylic acid catabolism|cinnamylic acid catabolic process|cinnamic acid degradation|phenylacrylic acid catabolism|cinnamic acid breakdown|phenylacrylic acid catabolic process|cinnamic acid catabolism													biological_process											owl:Class	
GO:0070768	biolink:NamedThing	synaptotagmin-synaptobrevin 2-SNAP-25-syntaxin-1a-syntaxin-1b-Unc13 complex	A SNARE complex that contains synaptotagmin, synaptobrevin 2 (VAMP2), SNAP-25, syntaxin 1a, syntaxin1b, and Unc13b (or orthologs thereof).	tmpzr1t_l9r_go_relaxed.owl	SNARE complex (Snap25, Syt1, Unc13b, Vamp2, Stx1b2, Stx1a)|Snap25-Syt1-Unc13b-Vamp2-Stx1b2-Stx1a complex							mah	2009-06-29T05:14:04Z					cellular_component											owl:Class	
GO:0008965	biolink:NamedThing	phosphoenolpyruvate-protein phosphotransferase activity	Catalysis of the reaction: phosphoenolpyruvate + protein L-histidine = pyruvate + protein N(pi)-phospho-L-histidine.	tmpzr1t_l9r_go_relaxed.owl	phosphoenolpyruvate--protein phosphatase activity|sugar--PEP phosphotransferase enzyme I activity|phosphoenolpyruvate sugar phosphotransferase enzyme I activity|phosphopyruvate--protein factor phosphotransferase activity|enzyme I of the phosphotransferase system|phosphopyruvate--protein phosphotransferase activity|phosphoenolpyruvate:protein-L-histidine N-pros-phosphotransferase activity|phosphoenolpyruvate:protein-L-histidine Npi-phosphotransferase activity				RHEA:23880|MetaCyc:2.7.3.9-RXN|EC:2.7.3.9									molecular_function											owl:Class	
GO:0061737	biolink:NamedThing	leukotriene signaling pathway	A series of molecular signals that proceeds with an activated receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-leukotriene interaction and ends with regulation of a downstream cellular process, e.g. transcription.	tmpzr1t_l9r_go_relaxed.owl								dph	2015-09-15T12:58:21Z					biological_process											owl:Class	
GO:0036469	biolink:NamedThing	L-tryptophan decarboxylase activity	Catalysis of the reaction: L-tryptophan + H+ = CO2 + tryptamine.	tmpzr1t_l9r_go_relaxed.owl					RHEA:30339|EC:4.1.1.105			bf	2014-07-21T09:22:24Z					molecular_function											owl:Class	
GO:0047426	biolink:NamedThing	ricinine nitrilase activity	Catalysis of the reaction: H2O + ricinine = NH3 + 3-carboxy-4-methoxy-N-methyl-2-pyridone.	tmpzr1t_l9r_go_relaxed.owl	ricinine aminohydrolase activity				MetaCyc:3.5.5.2-RXN|EC:3.5.5.2|RHEA:22704									molecular_function											owl:Class	
GO:0060373	biolink:NamedThing	regulation of ventricular cardiac muscle cell membrane depolarization	Any process that modulates the establishment or extent of a membrane potential in the depolarizing direction away from the resting potential in a ventricular cardiomyocyte.	tmpzr1t_l9r_go_relaxed.owl	regulation of ventricular cardiomyocyte membrane depolarization|electrocardiogram QRS complex|ventricular depolarization													biological_process											owl:Class	
GO:0042495	biolink:NamedThing	detection of triacyl bacterial lipopeptide	The series of events in which a triacylated bacterial lipoprotein stimulus is received by a cell and converted into a molecular signal. Triacylated bacterial lipoproteins are lipopeptides of bacterial origin containing a nonprotein moiety consisting of three acyl groups.	tmpzr1t_l9r_go_relaxed.owl	perception of triacylated bacterial lipopeptide|detection of triacylated bacterial lipoprotein|perception of triacylated bacterial lipoprotein					Note that bacterial lipopeptides are derived from bacterial lipoproteins, but the two terms are sometimes used interchangeably in the literature.								biological_process											owl:Class	
GO:0018387	biolink:NamedThing	N-terminal peptidyl-amino acid deamination to pyruvic acid	The oxidative deamination of N-terminal peptidyl-cysteine, or peptidyl-serine, to form pyruvic acid with an amide bond between its 1-carboxyl group and the N-terminal residue.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0127									biological_process											owl:Class	
GO:0030748	biolink:NamedThing	amine N-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + an amine = S-adenosyl-L-homocysteine + a methylated amine.	tmpzr1t_l9r_go_relaxed.owl	arylamine N-methyltransferase activity|S-adenosyl-L-methionine:amine N-methyltransferase activity|tryptamine N-methyltransferase activity|tryptamine methyltransferase|nicotine N-methyltransferase activity				MetaCyc:AMINE-N-METHYLTRANSFERASE-RXN|EC:2.1.1.49									molecular_function											owl:Class	
GO:0031560	biolink:NamedThing	cellular bud neck polarisome	Protein complex that has a role in determining cell polarity, found at the neck of a fungal bud before and during cytokinesis.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0045131	biolink:NamedThing	pre-mRNA branch point binding	Binding to a pre-mRNA branch point sequence, located upstream of the 3' splice site.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0052828	biolink:NamedThing	inositol-3,4-bisphosphate 4-phosphatase activity	Catalysis of the reaction: 1D-myo-inositol 3,4-bisphosphate + H2O = 1D-myo-inositol 3-phosphate + phosphate.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-1855202|RHEA:43388			ai	2011-11-29T09:57:00Z					molecular_function											owl:Class	
GO:0097678	biolink:NamedThing	SOCS family protein binding	Binding to a member of the suppressor of cytokine signaling (SOCS) family of proteins. SOCS represent an important mechanism to extinguish cytokine and growth factor receptor signaling. Individual SOCS proteins are typically induced by specific cytokines and growth factors, thereby generating a negative feedback loop. SOCS proteins have important functions in development and homeostasis, and in disease, particularly tumor suppression and anti-inflammatory functions.	tmpzr1t_l9r_go_relaxed.owl	suppressor of cytokine signaling family protein binding							pr	2014-11-04T11:32:49Z					molecular_function											owl:Class	
GO:0036181	biolink:NamedThing	protein localization to linear element	A cellular protein localization process in which a protein is transported to, or maintained at, a linear element. A linear element is a proteinaceous scaffold associated with S. pombe chromosomes during meiotic prophase.	tmpzr1t_l9r_go_relaxed.owl	protein localisation to linear element							bf	2012-03-30T04:14:17Z					biological_process											owl:Class	
GO:2001071	biolink:NamedThing	maltoheptaose binding	Binding to maltoheptaose.	tmpzr1t_l9r_go_relaxed.owl								jl	2011-09-14T12:04:30Z					molecular_function											owl:Class	
GO:0048331	biolink:NamedThing	axial mesoderm structural organization	The process that contributes to the act of creating the structural organization of the axial mesoderm. This process pertains to the physical shaping of a rudimentary structure.	tmpzr1t_l9r_go_relaxed.owl	axial mesoderm structural organisation													biological_process											owl:Class	
GO:0004060	biolink:NamedThing	arylamine N-acetyltransferase activity	Catalysis of the reaction: acetyl-CoA + an arylamine = CoA + an N-acetylarylamine.	tmpzr1t_l9r_go_relaxed.owl	beta-naphthylamine N-acetyltransferase activity|acetyl CoA-arylamine N-acetyltransferase activity|arylamine acetyltransferase activity|4-aminobiphenyl N-acetyltransferase activity|2-naphthylamine N-acetyltransferase activity|p-aminosalicylate N-acetyltransferase activity|acetyl-CoA:arylamine N-acetyltransferase activity|arylamine acetylase activity|indoleamine N-acetyltransferase activity				EC:2.3.1.5|Reactome:R-HSA-174967|RHEA:16613|Reactome:R-HSA-174963|UM-BBD_enzymeID:e0341|MetaCyc:ARYLAMINE-N-ACETYLTRANSFERASE-RXN									molecular_function											owl:Class	
GO:0090577	biolink:NamedThing	RNA polymerase IV transcription regulator complex	A transcription factor complex that acts at a regulatory region of a gene transcribed by RNA polymerase IV.	tmpzr1t_l9r_go_relaxed.owl	RNA polymerase IV transcription factor complex							tb	2014-05-09T14:04:37Z					cellular_component											owl:Class	
GO:0007075	biolink:NamedThing	positive regulation of transcription involved in exit from mitosis, from RNA polymerase III promoter	Any process that increases the frequency, rate or extent of transcription from an RNA polymerase III promoter as the cell leaves M phase. M phase is the part of the mitotic cell cycle during which mitosis and cytokinesis take place.	tmpzr1t_l9r_go_relaxed.owl	activation of transcription on exit from mitosis, from RNA polymerase III promoter|activation of transcription on exit from mitosis, from Pol III promoter													biological_process											owl:Class	
GO:0008752	biolink:NamedThing	FMN reductase activity	Catalysis of the reaction: FMNH2 + NAD(P)+ = FMN + NAD(P)H + H+.	tmpzr1t_l9r_go_relaxed.owl	riboflavine mononucleotide reductase activity|NAD(P)H-dependent FMN reductase activity|riboflavin mononucleotide (reduced nicotinamide adenine dinucleotide (phosphate)) reductase activity|flavin mononucleotide reductase activity|NAD(P)H(2) dehydrogenase (FMN) activity|flavine mononucleotide reductase activity|NAD(P)H2 dehydrogenase (FMN)|riboflavin mononucleotide reductase activity|NAD(P)H dehydrogenase (FMN) activity|NAD(P)H(2):FMN oxidoreductase activity|FMNH2:NAD(P)+ oxidoreductase activity|NAD(P)H2:FMN oxidoreductase activity|NAD(P)H:flavin oxidoreductase activity|NAD(P)H-FMN reductase activity|SsuE|NAD(P)H:FMN oxidoreductase activity				EC:1.5.1.39									molecular_function											owl:Class	
GO:0000721	biolink:NamedThing	(R,R)-butanediol dehydrogenase activity	Catalysis of the reversible reaction: (R,R)-butane-2,3-diol + NAD+ = (R)-acetoin + NADH + H(+).	tmpzr1t_l9r_go_relaxed.owl	aminopropanol oxidoreductase activity|butyleneglycol dehydrogenase activity|(R)-2,3-butanediol dehydrogenase activity|1-amino-2-propanol dehydrogenase activity|D-butanediol dehydrogenase activity|diacetyl (acetoin) reductase activity|(R)-diacetyl reductase activity|D-1-amino-2-propanol dehydrogenase activity|butylene glycol dehydrogenase activity|D-aminopropanol dehydrogenase activity|D-(-)-butanediol dehydrogenase activity|1-amino-2-propanol oxidoreductase activity|D-1-amino-2-propanol:NAD(2) oxidoreductase activity|2,3-butanediol dehydrogenase activity				EC:1.1.1.4|RHEA:24340|MetaCyc:RR-BUTANEDIOL-DEHYDROGENASE-RXN									molecular_function											owl:Class	
GO:0004643	biolink:NamedThing	phosphoribosylaminoimidazolecarboxamide formyltransferase activity	Catalysis of the reaction: 10-formyltetrahydrofolate + 5'-phosphoribosyl-5-amino-4-imidazolecarboxamide = tetrahydrofolate + 5'-phosphoribosyl-5-formamido-4-imidazolecarboxamide.	tmpzr1t_l9r_go_relaxed.owl	aminoimidazolecarboxamide ribonucleotide transformylase activity|5-amino-4-imidazolecarboxamide ribonucleotide transformylase activity|10-formyltetrahydrofolate:5'-phosphoribosyl-5-amino-4-imidazolecarboxamide formyltransferase activity|10-formyltetrahydrofolate:5'-phosphoribosyl-5-amino-4-imidazole-carboxamide N-formyltransferase activity|5'-phosphoribosyl-5-amino-4-imidazolecarboxamide formyltransferase activity|5-amino-1-ribosyl-4-imidazolecarboxamide 5'-phosphate transformylase activity|AICAR formyltransferase activity|AICAR transformylase activity|5-amino-4-imidazolecarboxamide ribotide transformylase activity				EC:2.1.2.3|MetaCyc:AICARTRANSFORM-RXN|RHEA:22192|Reactome:R-HSA-73798									molecular_function											owl:Class	
GO:0050664	biolink:NamedThing	oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces an oxygen molecule.	tmpzr1t_l9r_go_relaxed.owl	oxidoreductase activity, acting on NADH or NADPH, oxygen as acceptor				EC:1.6.3.-									molecular_function											owl:Class	
GO:0070467	biolink:NamedThing	RC-1 DNA recombination complex	A protein complex that contains DNA ligase III, DNA polymerase epsilon, a 5'-3' exonuclease, and the SMC1 and SMC2 proteins, and is involved in recombinational repair of deletions and gaps in DNA.	tmpzr1t_l9r_go_relaxed.owl	RC-1 complex (recombination complex 1)|DNA recombination complex RC-1													cellular_component											owl:Class	
GO:0102889	biolink:NamedThing	beta-elemene synthase activity	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate <=> beta-elemene + diphosphoric acid.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-8432									molecular_function											owl:Class	
GO:0098726	biolink:NamedThing	symmetric division of skeletal muscle satellite stem cell	The symmetric division of a skeletal muscle satellite stem cell, resulting in two skeletal muscle satellite stem cells.  This process is involved in amplification of the pool of these cells.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0000830	biolink:NamedThing	inositol hexakisphosphate 4-kinase activity	Catalysis of the reaction: ATP + 1D-myo-inositol hexakisphosphate = ADP + 4-diphospho-1D-myo-inositol (1,2,3,5,6)pentakisphosphate.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0042193	biolink:NamedThing	methylmercury catabolic process	The chemical reactions and pathways resulting in the breakdown of methylmercury (MeHg+), a highly toxic organometal.	tmpzr1t_l9r_go_relaxed.owl	methylmercury catabolism|methylmercury degradation|methylmercury breakdown													biological_process											owl:Class	
GO:0102265	biolink:NamedThing	tRNA-dihydrouridine47 synthase activity	Catalysis of the reaction: a 5,6-dihydrouracil47 in tRNA + NAD(P) <=> H+ + a uracil47 in tRNA + NAD(P)H.	tmpzr1t_l9r_go_relaxed.owl					EC:1.3.1.89|MetaCyc:RXN-12457									molecular_function											owl:Class	
GO:0050147	biolink:NamedThing	nucleoside ribosyltransferase activity	Catalysis of the reaction: D-ribosyl-base1 + base2 = D-ribosyl-base2 + base1.	tmpzr1t_l9r_go_relaxed.owl	nucleoside N-ribosyltransferase activity|nucleoside:purine(pyrimidine) D-ribosyltransferase activity				MetaCyc:NUCLEOSIDE-RIBOSYLTRANSFERASE-RXN|EC:2.4.2.5									molecular_function											owl:Class	
GO:1902922	biolink:NamedThing	poly(3-hydroxyvalerate) metabolic process	The chemical reactions and pathways involving poly(3-hydroxyvalerate).	tmpzr1t_l9r_go_relaxed.owl	poly(3-hydroxyvalerate) metabolism							tt	2014-04-21T19:13:56Z					biological_process											owl:Class	
GO:0010342	biolink:NamedThing	endosperm cellularization	The separation of the multi-nucleate endosperm into individual cells. In many plant species, the endosperm that nurtures the embryo in the seed initially develops as a syncytium. This syncytial phase ends with simultaneous partitioning of the multi-nucleate cytoplasm into individual cells, a process referred to as cellularization.	tmpzr1t_l9r_go_relaxed.owl	cellularization of endosperm													biological_process											owl:Class	
GO:0014914	biolink:NamedThing	myoblast maturation involved in muscle regeneration	A developmental process, independent of morphogenetic (shape) change, that is required for a myoblast cell to attain its fully functional state involved in muscle regeneration. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0018289	biolink:NamedThing	molybdenum incorporation into metallo-sulfur cluster	The incorporation of molybdenum into a metallo-sulfur cluster.	tmpzr1t_l9r_go_relaxed.owl	molybdenum incorporation into metallo-sulphur cluster													biological_process											owl:Class	
GO:0019277	biolink:NamedThing	UDP-N-acetylgalactosamine biosynthetic process	The chemical reactions and pathways resulting in the formation of UDP-N-acetylgalactosamine, a substance composed of N-acetylgalactosamine, a common structural unit of oligosaccharides, in glycosidic linkage with uridine diphosphate.	tmpzr1t_l9r_go_relaxed.owl	UDP-N-acetylgalactosamine synthesis|UDP-N-acetylgalactosamine anabolism|UDP-N-acetylgalactosamine formation|UDP-N-acetylgalactosamine biosynthesis				MetaCyc:UDPNACETYLGALSYN-PWY									biological_process											owl:Class	
GO:0001052	biolink:NamedThing	plastid PEP RNA polymerase core enzyme binding	Binding to a bacterial-type plastid PEP RNA polymerase core enzyme, typically consisting of two alpha, one beta, one beta prime, and one double prime subunit.	tmpzr1t_l9r_go_relaxed.owl								krc	2010-09-23T02:49:31Z					molecular_function											owl:Class	
GO:0001000	biolink:NamedThing	bacterial-type RNA polymerase core enzyme binding	Binding to a bacterial-type RNA polymerase core enzyme, typically consisting of two alpha, one beta, one beta prime, and one omega subunit.	tmpzr1t_l9r_go_relaxed.owl	eubacterial-type RNA polymerase core enzyme binding					Should omega be included here?		krc	2010-08-17T04:59:00Z					molecular_function											owl:Class	
GO:0016267	biolink:NamedThing	O-glycan processing, core 1	The stepwise addition of carbohydrate or carbohydrate derivative residues to the initially added O-linked residue (usually GalNAc) to form the core 1 O-glycan structure, Gal-beta-(1->3)-GalNAc.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0047938	biolink:NamedThing	glucose-6-phosphate 1-epimerase activity	Catalysis of the reaction: alpha-D-glucose 6-phosphate = beta-D-glucose 6-phosphate.	tmpzr1t_l9r_go_relaxed.owl	glucose-6 phosphate 1-epimerase activity|D-glucose-6-phosphate 1-epimerase activity				EC:5.1.3.15|RHEA:16249|MetaCyc:GLUCOSE-6-PHOSPHATE-1-EPIMERASE-RXN									molecular_function											owl:Class	
GO:0098018	biolink:NamedThing	viral capsid, minor subunit	The part of the viral capsid that comprises the less common capsomere type. For example, in a T=3 icosahedral capsid, which is composed of 12 pentameric and 20 hexameric capsomeres, the pentameric capsomeres are minor subunits.	tmpzr1t_l9r_go_relaxed.owl	minor head protein|minor capsomere							bm	2012-07-19T11:28:18Z					cellular_component											owl:Class	
GO:0050216	biolink:NamedThing	propanediol-phosphate dehydrogenase activity	Catalysis of the reaction: NAD(+) + propane-1,2-diol 1-phosphate = H(+) + hydroxyacetone phosphate + NADH.	tmpzr1t_l9r_go_relaxed.owl					KEGG_REACTION:R04236|EC:1.1.1.7|MetaCyc:PROPANEDIOL-PHOSPHATE-DEHYDROGENASE-RXN|RHEA:21584									molecular_function											owl:Class	
GO:0061653	biolink:NamedThing	ISG15 conjugating enzyme activity	Isoenergetic transfer of ISG15 from one protein to another via the reaction X-ISG15 + Y -> Y-ISG15 + X, where both the X-ISG15 and Y-ISG15 linkages are thioester bonds between the C-terminal amino acid of ISG15 and a sulfhydryl side group of a cysteine residue.	tmpzr1t_l9r_go_relaxed.owl	E2							dph	2014-11-06T13:24:50Z					molecular_function											owl:Class	
GO:0034799	biolink:NamedThing	dihydride TNP tautomerase activity	Catalysis of the reaction: TNP dihydride Meisenheimer complex (aci form) = TNP dihydride Meisenheimer complex (nitro form).	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r1070									molecular_function											owl:Class	
GO:0046784	biolink:NamedThing	viral mRNA export from host cell nucleus	The directed movement of intronless viral mRNA from the host nucleus to the cytoplasm for translation.	tmpzr1t_l9r_go_relaxed.owl	intronless viral mRNA export out of nucleus|intronless viral mRNA-nucleus export|intronless viral mRNA export from host cell nucleus|intronless viral mRNA export from host nucleus|intronless viral mRNA transport from nucleus to cytoplasm													biological_process											owl:Class	
GO:0034931	biolink:NamedThing	1-hydroxypyrene methyltransferase activity	Catalysis of the reaction: 1-hydroxypyrene + XCH3 = 1-methoxypyrene + HX.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0953									molecular_function											owl:Class	
GO:0034855	biolink:NamedThing	4-AD 9alpha-hydroxylase activity	Catalysis of the reaction: androst-4-ene-3,17-dione + O2 + 2 H+ + 2 e- = 9alpha-hydroxy-4-androstene-3,17-dione + H2O.	tmpzr1t_l9r_go_relaxed.owl					EC:1.14.15.-|UM-BBD_reactionID:r1153									molecular_function											owl:Class	
GO:0102361	biolink:NamedThing	esculetin 4-O-beta-glucosyltransferase activity	Catalysis of the reaction: esculetin + UDP-alpha-D-glucose <=> 4-O-beta-D-glucosyl-esculetin + UDP + H+.	tmpzr1t_l9r_go_relaxed.owl					EC:2.4.1.126|MetaCyc:RXN-13471									molecular_function											owl:Class	
GO:0045925	biolink:NamedThing	positive regulation of female receptivity	Any process that activates or increases the receptiveness of a female to male advances.	tmpzr1t_l9r_go_relaxed.owl	activation of female receptivity|up-regulation of female receptivity|stimulation of female receptivity|up regulation of female receptivity|upregulation of female receptivity													biological_process											owl:Class	
GO:0007400	biolink:NamedThing	neuroblast fate determination	The cell fate determination process in which a cell becomes capable of differentiating autonomously into a neuroblast cell regardless of its environment; upon determination, the cell fate cannot be reversed. An example of this process is found in Mus musculus.	tmpzr1t_l9r_go_relaxed.owl	neuroblast cell fate determination|neuroblast identity determination											GO:0007408|GO:0043347|GO:0043348		biological_process											owl:Class	
GO:0060112	biolink:NamedThing	generation of ovulation cycle rhythm	The process which controls the timing of the type of sexual cycle seen in female mammals.	tmpzr1t_l9r_go_relaxed.owl	generation of menstrual cycle rhythm|generation of estrus cycle rhythm|generation of oestrus cycle rhythm													biological_process											owl:Class	
GO:0031465	biolink:NamedThing	Cul4B-RING E3 ubiquitin ligase complex	A ubiquitin ligase complex in which a cullin from the Cul4B subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by unknown subunits.	tmpzr1t_l9r_go_relaxed.owl	cullin-RING ligase 4B													cellular_component											owl:Class	
GO:1901705	biolink:NamedThing	L-isoleucine biosynthetic process	The chemical reactions and pathways resulting in the formation of L-isoleucine.	tmpzr1t_l9r_go_relaxed.owl	L-isoleucine biosynthesis|L-isoleucine formation|L-isoleucine synthesis|L-isoleucine anabolism							pde	2012-12-13T23:32:56Z					biological_process											owl:Class	
GO:0090593	biolink:NamedThing	peptidyl-histidine autophosphorylation	The phosphorylation by a protein of one or more of its own histidine residues, or a histidine residue on an identical protein.	tmpzr1t_l9r_go_relaxed.owl								tb	2014-06-06T14:19:46Z					biological_process											owl:Class	
GO:0034576	biolink:NamedThing	N-isopropylacetanilide amidohydrolase activity	Catalysis of the reaction: N-isopropylacetanilide + OH- = N-isopropylaniline + acetate.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0913									molecular_function											owl:Class	
GO:0032840	biolink:NamedThing	intramolecular proline-rich ligand binding	Binding to a proline-rich region within the same polypeptide.	tmpzr1t_l9r_go_relaxed.owl	intramolecular proline-rich region binding													molecular_function											owl:Class	
GO:2000018	biolink:NamedThing	regulation of male gonad development	Any process that modulates the frequency, rate or extent of male gonad development.	tmpzr1t_l9r_go_relaxed.owl	regulation of testis development|regulation of testicular development							jl	2010-07-15T03:29:05Z					biological_process											owl:Class	
GO:0048156	biolink:NamedThing	tau protein binding	Binding to tau protein. tau is a microtubule-associated protein, implicated in Alzheimer's disease, Down Syndrome and ALS.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1905573	biolink:NamedThing	ganglioside GM1 binding	Binding to ganglioside GM1.	tmpzr1t_l9r_go_relaxed.owl								pga	2016-10-19T10:57:28Z					molecular_function											owl:Class	
GO:1901148	biolink:NamedThing	gene expression involved in extracellular matrix organization	Any gene expression that is involved in extracellular matrix organization. Gene expression includes both transcription to produce an RNA transcript, and the translation of that mRNA into protein. Protein maturation is included in gene expression when required to form an active form of a product from an inactive precursor form.	tmpzr1t_l9r_go_relaxed.owl	expression of extracellular matrix proteins|extracellular matrix protein production							bf	2012-07-16T03:29:30Z					biological_process											owl:Class	
GO:0062233	biolink:NamedThing	F2-isoprostane catabolic process	The chemical reactions and pathways resulting in the breakdown of F2-isoprostane.	tmpzr1t_l9r_go_relaxed.owl								dph	2020-03-23T15:24:38Z					biological_process											owl:Class	
GO:0039699	biolink:NamedThing	viral mRNA cap methylation	Methylation of the 2'-O-ribose of the first or second transcribed nucleotide of a viral mRNA. Methylation allows evasion of the host innate immune response, which degrades cap0 (non-methylated) mRNAs.	tmpzr1t_l9r_go_relaxed.owl	IFIT mRNA restriction evasion by virus							bf	2013-11-06T14:39:17Z					biological_process											owl:Class	
GO:0030485	biolink:NamedThing	smooth muscle contractile fiber	The contractile fiber of smooth muscle cells.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0052878	biolink:NamedThing	linoleate 8R-lipoxygenase activity	Catalysis of the reaction: O(2) + linoleate = (8R,9Z,12Z)-8-hydroperoxyoctadeca-9,12-dienoate.	tmpzr1t_l9r_go_relaxed.owl	5,8-LDS (bifunctional enzyme) activity|7,8-linoleate diol synthase (bifunctional enzyme) activity|5,8-linoleate diol synthase (bifunctional enzyme) activity|linoleate diol synthase activity|7,8-LDS (bifunctional enzyme) activity				KEGG_REACTION:R07061|EC:1.13.11.60|RHEA:25395|MetaCyc:1.13.11.44-RXN									molecular_function											owl:Class	
GO:0047771	biolink:NamedThing	carboxymethylhydantoinase activity	Catalysis of the reaction: L-5-carboxymethylhydantoin + H(2)O = N-carbamoyl-L-aspartate + H(+).	tmpzr1t_l9r_go_relaxed.owl	L-5-carboxymethylhydantoin amidohydrolase activity|hydantoin hydrolase activity				MetaCyc:CARBOXYMETHYLHYDANTOINASE-RXN|EC:3.5.2.4|KEGG_REACTION:R02284|RHEA:12028									molecular_function											owl:Class	
GO:0062010	biolink:NamedThing	primitive palate development	The biological process whose specific outcome is the progression of the primitive palate from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure.	tmpzr1t_l9r_go_relaxed.owl								dph	2018-02-26T23:00:48Z					biological_process											owl:Class	
GO:1904016	biolink:NamedThing	response to Thyroglobulin triiodothyronine	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a Thyroglobulin triiodothyronine stimulus.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-03-06T19:34:07Z					biological_process											owl:Class	
GO:0102391	biolink:NamedThing	decanoate-CoA ligase activity	Catalysis of the reaction: ATP + decanoate + CoA = AMP +  diphosphate + decanoyl-CoA.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/18967			MetaCyc:RXN-13614|RHEA:33627									molecular_function											owl:Class	
GO:0003327	biolink:NamedThing	type B pancreatic cell fate commitment	The commitment of a cell to a type B pancreatic cell fate and its capacity to differentiate into a type B pancreatic cell. A type B pancreatic cell is a cell located towards center of the islets of Langerhans that secretes insulin.	tmpzr1t_l9r_go_relaxed.owl	pancreatic B cell fate commitment							dph	2009-11-02T08:31:24Z					biological_process											owl:Class	
GO:0019328	biolink:NamedThing	anaerobic gallate catabolic process	The chemical reactions and pathways resulting in the breakdown of gallate, the anion of gallic acid, in the absence of oxygen.	tmpzr1t_l9r_go_relaxed.owl	anaerobic gallic acid catabolism|anaerobic gallic acid catabolic process|anaerobic gallate degradation|anaerobic gallate catabolism|gallate fermentation|anaerobic gallate breakdown				MetaCyc:P3-PWY									biological_process											owl:Class	
GO:0047204	biolink:NamedThing	chlorogenate-glucarate O-hydroxycinnamoyltransferase activity	Catalysis of the reaction: D-glucarate + chlorogenate = (-)-quinate + 2-O-caffeoylglucarate.	tmpzr1t_l9r_go_relaxed.owl	chlorogenate:glucarate caffeoyltransferase activity|chlorogenate:glucarate O-(hydroxycinnamoyl)transferase activity|chlorogenic acid:glucaric acid O-caffeoyltransferase activity				KEGG_REACTION:R02998|MetaCyc:2.3.1.98-RXN|EC:2.3.1.98|RHEA:23204									molecular_function											owl:Class	
GO:0016270	biolink:NamedThing	O-glycan processing, core 4	The stepwise addition of carbohydrate or carbohydrate derivative residues to the initially added O-linked residue (usually GalNAc) to form the core 4 O-glycan structure, GlcNAc-beta-(1->6)[GalNAc-beta-(1->3)]-GalNAc.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0004397	biolink:NamedThing	histidine ammonia-lyase activity	Catalysis of the reaction: L-histidine = urocanate + NH3.	tmpzr1t_l9r_go_relaxed.owl	histidine alpha-deaminase activity|histidinase activity|L-histidine ammonia-lyase (urocanate-forming)|histidase activity|L-histidine ammonia-lyase activity				RHEA:21232|Reactome:R-HSA-70899|MetaCyc:HISTIDINE-AMMONIA-LYASE-RXN|EC:4.3.1.3									molecular_function											owl:Class	
GO:0035612	biolink:NamedThing	AP-2 adaptor complex binding	Binding to an AP-2 adaptor complex. The AP-2 adaptor complex is a heterotetrameric AP-type membrane coat adaptor complex that consists of alpha, beta2, mu2 and sigma2 subunits and links clathrin to the membrane surface of a vesicle. In at least humans, the AP-2 complex can be heterogeneric due to the existence of multiple subunit isoforms encoded by different alpha genes (alphaA and alphaC).	tmpzr1t_l9r_go_relaxed.owl	AP-2 clathrin adaptor complex binding							bf	2010-11-25T03:51:17Z					molecular_function											owl:Class	
GO:0071759	biolink:NamedThing	IgX immunoglobulin complex	A protein complex composed of two identical immunoglobulin heavy chains of the IgX isotype and two identical immunoglobulin light chains, held together by disulfide bonds. An IgX immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.	tmpzr1t_l9r_go_relaxed.owl						Note that an IgX immunoglobulin complex has the function of antigen binding if a suitable antigen is available. Note that IgX is found in amphibians.		mah	2010-03-24T01:44:53Z					cellular_component											owl:Class	
GO:0102436	biolink:NamedThing	7-methylmyricetin 4'-O-methyltransferase activity	Catalysis of the reaction: 7-O-methylmyricetin + S-adenosyl-L-methionine  <=> 7,4'-dimethylmyricetin + S-adenosyl-L-homocysteine  + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-13911									molecular_function											owl:Class	
GO:0045157	biolink:NamedThing	electron transporter, transferring electrons within the noncyclic electron transport pathway of photosynthesis activity	Enables the directed movement of electrons within the noncyclic electron transport pathway of photosynthesis.	tmpzr1t_l9r_go_relaxed.owl	cytochrome													molecular_function											owl:Class	
GO:0016402	biolink:NamedThing	pristanoyl-CoA oxidase activity	Catalysis of the reaction: pristanoyl-CoA + O2 = trans-2,3-dehydropristanoyl-CoA + hydrogen peroxide.	tmpzr1t_l9r_go_relaxed.owl					RHEA:40459|Reactome:R-HSA-389889|Reactome:R-HSA-389891									molecular_function											owl:Class	
GO:0090722	biolink:NamedThing	receptor-receptor interaction	The aggregation, arrangement and bonding together of two or more different receptor complexes that individually undergo combination with a hormone, neurotransmitter, drug or intracellular messenger to form a higher level receptor complex. The formation of the higher level complex initiates a change in cell function.	tmpzr1t_l9r_go_relaxed.owl	hetero-receptor complex formation							tb	2016-11-11T17:41:56Z					molecular_function											owl:Class	
GO:0061993	biolink:NamedThing	calcium:proton antiporter complex	A protein complex that enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Ca2+(in) + H+(out) = Ca2+(out) + H+(in).	tmpzr1t_l9r_go_relaxed.owl	CAX1 homodimer|CAX1-CAX3 complex|CAX3 homodimer							dph	2018-02-16T02:17:10Z					cellular_component											owl:Class	
GO:0015987	biolink:NamedThing	GTP synthesis coupled proton transport	The transport of protons across a membrane to generate an electrochemical gradient (proton-motive force) that powers GTP synthesis.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0052602	biolink:NamedThing	4-chloronitrobenzene nitroreductase activity	Catalysis of the reaction: 4-chloronitrobenzene + NADPH + H+ = 1-chloro-4-nitrosobenzene + NADP+ + H2O.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_enzymeID:e0245|MetaCyc:RXN-8833									molecular_function											owl:Class	
GO:0050019	biolink:NamedThing	L-arabinitol 4-dehydrogenase activity	Catalysis of the reaction: L-arabinitol + NAD(+) = L-xylulose + H(+) + NADH.	tmpzr1t_l9r_go_relaxed.owl					EC:1.1.1.12|MetaCyc:L-ARABINITOL-4-DEHYDROGENASE-RXN|KEGG_REACTION:R01903|RHEA:16381									molecular_function											owl:Class	
GO:0022020	biolink:NamedThing	medial ganglionic eminence cell proliferation	The multiplication or reproduction of medial ganglionic eminence cells, resulting in the expansion of a cell population.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0051742	biolink:NamedThing	2-methyl-6-solanyl-1,4-benzoquinone methyltransferase activity	Catalysis of the reaction: 2-methyl-6-solanyl-1,4-benzoquinone + S-adenosyl-methionine = 2,3-dimethyl-6-solanyl-1,4-benzoquinone + S-adenosyl-homocysteine.	tmpzr1t_l9r_go_relaxed.owl	MSBQ methyltransferase activity				RHEA:37999|MetaCyc:RXN-2762									molecular_function											owl:Class	
GO:0061689	biolink:NamedThing	tricellular tight junction	An specialized occluding junction where three epithelial cells meet. It is composed of a branching network of sealing strands that run perpendicularly to the bicellular tight junction at the point of contact between three epithelial cells in an epithelial sheet.	tmpzr1t_l9r_go_relaxed.owl								dph	2015-04-12T10:34:19Z					cellular_component											owl:Class	
GO:0050005	biolink:NamedThing	isohexenylglutaconyl-CoA hydratase activity	Catalysis of the reaction: 3-hydroxy-3-(4-methylpent-3-en-1-yl)glutaryl-CoA = 3-(4-methylpent-3-en-1-yl)pent-2-enedioyl-CoA + H(2)O.	tmpzr1t_l9r_go_relaxed.owl	3-hydroxy-3-isohexenylglutaryl-CoA-hydrolase activity|3-hydroxy-3-(4-methylpent-3-en-1-yl)glutaryl-CoA hydro-lyase activity|3-hydroxy-3-(4-methylpent-3-en-1-yl)glutaryl-CoA hydro-lyase [3-(4-methylpent-3-en-1-yl)pent-2-enedioyl-CoA-forming]|isohexenylglutaconyl coenzyme A hydratase activity|beta-isohexenylglutaconyl-CoA-hydratase activity				KEGG_REACTION:R03493|EC:4.2.1.57|MetaCyc:ISOHEXENYLGLUTACONYL-COA-HYDRATASE-RXN|RHEA:24144|UM-BBD_reactionID:r1167									molecular_function											owl:Class	
GO:0102117	biolink:NamedThing	gibberellin A9 carboxyl methyltransferase activity	Catalysis of the reaction: gibberellin A9 + S-adenosyl-L-methionine  <=> gibberellin A9 methyl ester + S-adenosyl-L-homocysteine.	tmpzr1t_l9r_go_relaxed.owl					RHEA:36119|MetaCyc:RXN-11358|EC:2.1.1.275									molecular_function											owl:Class	
GO:0045004	biolink:NamedThing	DNA replication proofreading	Correction of replication errors by DNA polymerase using a 3'-5' exonuclease activity.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0008847	biolink:NamedThing	Enterobacter ribonuclease activity	Catalysis of the endonucleolytic cleavage to 3'-phosphomononucleotides and 3'-phosphooligonucleotides with 2',3'-cyclic phosphate intermediates.	tmpzr1t_l9r_go_relaxed.owl	Enterobacter RNase activity				MetaCyc:3.1.27.6-RXN|EC:4.6.1.21									molecular_function											owl:Class	
GO:0099071	biolink:NamedThing	dynamic microtubule bundle	A microtubule bundle that undergoes changes in length, and in which microtubule sliding takes place.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0003120	biolink:NamedThing	regulation of vasoconstriction by circulating epinephrine	Any process that modulates the frequency, rate or extent of reductions in the diameter of blood vessels as a result of secretion of epinephrine into the bloodstream.	tmpzr1t_l9r_go_relaxed.owl	regulation of vasoconstriction by circulating adrenaline													biological_process											owl:Class	
GO:1990738	biolink:NamedThing	pseudouridine 5'-phosphatase activity	Catalysis of the reaction: pseudouridine 5'-phosphate + H2O = pseudouridine + phosphate.	tmpzr1t_l9r_go_relaxed.owl					RHEA:10944|EC:3.1.3.96			vw	2015-05-02T11:05:50Z					molecular_function											owl:Class	
GO:0004156	biolink:NamedThing	dihydropteroate synthase activity	Catalysis of the reaction: 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + 4-aminobenzoate = diphosphate + dihydropteroate.	tmpzr1t_l9r_go_relaxed.owl	7,8-dihydropteroic acid synthetase activity|DHPS activity|(2-amino-4-hydroxy-7,8-dihydropteridin-6-yl)methyl-diphosphate:4-aminobenzoate 2-amino-4-hydroxydihydropteridine-6-methenyltransferase activity|7,8-dihydropteroate synthase activity|2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine-diphosphate:4-aminobenzoate 2-amino-4-hydroxydihydropteridine-6-methenyltransferase activity|dihydropteroic synthetase activity|dihydropteroate pyrophosphorylase activity|dihydropteroate synthetase activity|7,8-dihydropteroate synthetase activity|dihydropteroate diphosphorylase activity				MetaCyc:H2PTEROATESYNTH-RXN|RHEA:19949|EC:2.5.1.15									molecular_function											owl:Class	
GO:0052715	biolink:NamedThing	mannosyl-diinositol phosphorylceramide phospholipase activity	Catalysis of the reaction: mannosyl-diinositol phosphorylceramide + H2O = C26-phytoceramide + mannosyldiphosphorylinositol.	tmpzr1t_l9r_go_relaxed.owl								ai	2011-08-05T08:02:57Z					molecular_function											owl:Class	
GO:0007489	biolink:NamedThing	maintenance of imaginal histoblast diploidy	The negative regulation of the differentiation of polytenized larval hypodermal cells from abdominal histoblasts. The abdominal histoblasts remain a small cluster of diploid cells among the polytenized larval hypodermal cells.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0018484	biolink:NamedThing	4-hydroxybenzaldehyde dehydrogenase activity	Catalysis of the reaction: 4-hydroxybenzaldehyde + NAD+ + H2O = 4-hydroxybenzoate + NADH + H+.	tmpzr1t_l9r_go_relaxed.owl	3-hydroxybenzaldehyde:NAD+ oxidoreductase activity|p-hydroxybenzaldehyde dehydrogenase activity				EC:1.2.1.64|UM-BBD_reactionID:r0273|MetaCyc:HYDROXYBENZALDEHYDE-OXIDATION-NAD-RXN|RHEA:20305									molecular_function											owl:Class	
GO:0006147	biolink:NamedThing	guanine catabolic process	The chemical reactions and pathways resulting in the breakdown of guanine, 2-amino-6-hydroxypurine, a purine that is one of the five main bases found in nucleic acids and a component of a number of phosphorylated guanosine derivatives whose metabolic or regulatory functions are important.	tmpzr1t_l9r_go_relaxed.owl	guanine catabolism|guanine degradation|guanine breakdown													biological_process											owl:Class	
GO:0005596	biolink:NamedThing	collagen type XIV trimer	A collagen homotrimer of alpha1(XIV) chains; type XIV collagen triple helices may link sheet-forming or fibrillar collagens to other structures.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0035301	biolink:NamedThing	Hedgehog signaling complex	A multiprotein complex that binds microtubules in a Hedgehog-dependent manner, and is required for signal transduction by members of the Hedgehog family of proteins. The core components of the complex are the serine/threonine protein kinase Fused, the kinesin motor protein Costal2 (Cos2), and a zinc finger transcription factor (Gli family members in humans, and Cubitus interruptus (Ci) in Drosophila).	tmpzr1t_l9r_go_relaxed.owl	Hedgehog signalling complex|HSC													cellular_component											owl:Class	
GO:0062046	biolink:NamedThing	dehydropipecolic acid reductase	Catalysis of the reaction: dehydropipecolic acid + NAD(P)H + H+ = L-pipecolic acid + NAD(P)+.	tmpzr1t_l9r_go_relaxed.owl								dph	2018-05-11T12:16:00Z					molecular_function											owl:Class	
GO:1901051	biolink:NamedThing	atropine biosynthetic process	The chemical reactions and pathways resulting in the formation of atropine.	tmpzr1t_l9r_go_relaxed.owl	atropine formation|atropine biosynthesis|atropine anabolism|atropine synthesis							yaf	2012-06-28T04:51:59Z					biological_process											owl:Class	
GO:0033829	biolink:NamedThing	O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity	Catalysis of the transfer of a beta-D-GlcNAc residue from UDP-D-GlcNAc to the fucose residue of a fucosylated protein acceptor.	tmpzr1t_l9r_go_relaxed.owl	UDP-D-GlcNAc:O-L-fucosylpeptide 3-beta-N-acetyl-D-glucosaminyltransferase activity|O-fucosylpeptide beta-1,3-N-acetylglucosaminyltransferase activity				MetaCyc:2.4.1.222-RXN|EC:2.4.1.222|Reactome:R-HSA-5096538|Reactome:R-HSA-1912355									molecular_function											owl:Class	
GO:0042351	biolink:NamedThing	'de novo' GDP-L-fucose biosynthetic process	The chemical reactions and pathways resulting in the formation of GDP-L-fucose from GDP-D-mannose via GDP-4-dehydro-6-deoxy-D-mannose, requiring the functions of GDP-mannose 4,6-dehydratase (EC:4.2.1.47) and GDP-L-fucose synthase (EC:1.1.1.271).	tmpzr1t_l9r_go_relaxed.owl	GDP-L-fucose biosynthetic process, de novo pathway|GDP-L-fucose biosynthesis, de novo pathway|'de novo' GDP-L-fucose formation|'de novo' GDP-L-fucose biosynthesis|'de novo' GDP-L-fucose anabolism|'de novo' GDP-L-fucose synthesis				MetaCyc:PWY-66									biological_process											owl:Class	
GO:1990533	biolink:NamedThing	Dom34-Hbs1 complex	A protein complex consisting of one subunit known as Dom34 or Pelota that has similarity to translation termination factor eRF1, and another subunit, Hbs1, that is a GTPase with similarity to translation termination factor eRF3. The Dom34-Hbs1 complex has a role in cotranslational mRNA quality control by promoting ribosomal subunit dissociation and peptidyl-tRNA release when translation is stalled, facilitating no-go decay and nonstop decay.	tmpzr1t_l9r_go_relaxed.owl	Dom34:Hbs1 complex							mcc	2014-11-07T20:49:03Z					cellular_component											owl:Class	
GO:0070294	biolink:NamedThing	renal sodium ion absorption	A renal system process in which sodium ions are taken up from the collecting ducts and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures.	tmpzr1t_l9r_go_relaxed.owl	nephron sodium ion absorption|renal sodium ion reabsorption													biological_process											owl:Class	
GO:0050079	biolink:NamedThing	acetylenecarboxylate hydratase activity, producing 3-oxopropanoate	Catalysis of the reaction: 3-oxopropanoate = propynoate + H2O.	tmpzr1t_l9r_go_relaxed.owl	acetylenecarboxylate hydratase activity, producing malonate-semialdehyde|3-oxopropanoate hydro-lyase (propynoate-forming)|acetylenemonocarboxylate hydrase activity|acetylenecarboxylate hydratase activity|malonate-semialdehyde dehydratase activity|acetylmonocarboxylic acid hydrase activity|acetylenemonocarboxylate hydratase activity|alkynoate hydratase activity|3-oxopropanoate hydro-lyase activity				RHEA:17957|MetaCyc:MALONATE-SEMIALDEHYDE-DEHYDRATASE-RXN|EC:4.2.1.27	Note that this function was formerly EC:4.2.1.71.						GO:0047607		molecular_function											owl:Class	
GO:1902051	biolink:NamedThing	(25S)-Delta(4)-dafachronate binding	Binding to (25S)-Delta(4)-dafachronate.	tmpzr1t_l9r_go_relaxed.owl								ab	2013-04-11T08:33:41Z					molecular_function											owl:Class	
GO:0042075	biolink:NamedThing	nickel incorporation into nickel-iron-sulfur cluster via pentakis-L-cysteinyl L-histidino nickel tetrairon pentasulfide	The incorporation of nickel into a nickel-iron-sulfur cluster via pentakis-L-cysteinyl L-histidino nickel tetrairon pentasulfide, found in carbon monoxide dehydrogenase.	tmpzr1t_l9r_go_relaxed.owl	nickel incorporation into nickel-iron-sulphur cluster via pentakis-L-cysteinyl L-histidino nickel tetrairon pentasulphide				RESID:AA0310									biological_process											owl:Class	
GO:0030553	biolink:NamedThing	cGMP binding	Binding to cGMP, the nucleotide cyclic GMP (guanosine 3',5'-cyclophosphate).	tmpzr1t_l9r_go_relaxed.owl	3',5' cGMP binding|cyclic GMP binding|3',5'-cGMP binding													molecular_function											owl:Class	
GO:0051634	biolink:NamedThing	inhibition of acetylcholine uptake	Any process that prevents the activation of the directed movement of acetylcholine into a cell.	tmpzr1t_l9r_go_relaxed.owl	inhibition of acetylcholine import													biological_process											owl:Class	
GO:0033693	biolink:NamedThing	neurofilament bundle assembly	The assembly of neurofilaments into bundles, in which the filaments are longitudinally oriented, with numerous crossbridges between them. Neurofilament bundles may be cross-linked to each other, to membrane-bounded organelles or other cytoskeletal structures such as microtubules.	tmpzr1t_l9r_go_relaxed.owl	NF bundle assembly													biological_process											owl:Class	
GO:0050385	biolink:NamedThing	ureidoglycolate lyase activity	Catalysis of the reaction: (S)-ureidoglycolate = glyoxylate + urea.	tmpzr1t_l9r_go_relaxed.owl	(S)-ureidoglycolate urea-lyase activity|ureidoglycolate hydrolase activity|ureidoglycolatase activity|(S)-ureidoglycolate urea-lyase (glyoxylate-forming)|ureidoglycolase activity				RHEA:11304|KEGG_REACTION:R00776|EC:4.3.2.3|MetaCyc:UREIDOGLYCOLATE-LYASE-RXN	Take care to annotate to the reaction, not simply by enzyme name. Note that the name "ureidoglycolate hydrolase" (listed as a synonym here) has variously been used to refer to two distinctly different enzymes. Both enzymes act on ureidoglycolate and produce glyoxylate, but the mechanism and reaction products are different. The "ureidoglycolate hydrolase" listed in the Enzyme commission (EC) is a ureidoglycolate amidohydrolase, releasing ammonia, (EC:3.5.3.19 ; GO:0004848). The "ureidoglycolate hydrolase" characterized in PMID:3915539 (published prior to the EC designation of EC:3.5.3.19) is a ureidoglycolate lyase, releasing urea (EC:4.3.2.3 ; GO:0050385). The inappropriate labelling of ureidoglycolate lyase as EC:3.5.3.19 has caused much confusion in the literature (see PMID:24107613). Take care to correctly annotate based on the reaction products, rather than name.								molecular_function											owl:Class	
GO:1904620	biolink:NamedThing	cellular response to dimethyl sulfoxide	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dimethyl sulfoxide stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to DMSO							sl	2015-08-27T19:14:07Z					biological_process											owl:Class	
GO:0019325	biolink:NamedThing	anaerobic fructose catabolic process	The chemical reactions and pathways resulting in the breakdown of fructose that occurs in the absence of oxygen.	tmpzr1t_l9r_go_relaxed.owl	anaerobic fructose degradation|anaerobic fructose breakdown|anaerobic fructose catabolism				MetaCyc:ANAEROFRUCAT-PWY									biological_process											owl:Class	
GO:0004150	biolink:NamedThing	dihydroneopterin aldolase activity	Catalysis of the reaction: 2-amino-4-hydroxy-6-(D-erythro-1,2,3-trihydroxypropyl)-7,8-dihydropteridine = 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine + glycolaldehyde.	tmpzr1t_l9r_go_relaxed.owl	2-amino-4-hydroxy-6-(D-erythro-1,2,3-trihydroxypropyl)-7,8-dihydropteridine glycolaldehyde-lyase (2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine-forming)|2-amino-4-hydroxy-6-(D-erythro-1,2,3-trihydroxypropyl)-7,8-dihydropteridine glycolaldehyde-lyase activity				RHEA:10540|MetaCyc:H2NEOPTERINALDOL-RXN|EC:4.1.2.25									molecular_function											owl:Class	
GO:1904928	biolink:NamedThing	coreceptor activity involved in canonical Wnt signaling pathway	Any coreceptor activity that is involved in a canonical Wnt signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	coreceptor, soluble ligand activity involved in frizzled-1 receptor signaling pathway|coreceptor, insoluble ligand activity involved in Wnt receptor signalling pathway through beta-catenin|coreceptor, insoluble ligand activity involved in canonical Wnt-activated signaling pathway|coreceptor activity involved in canonical Wnt receptor signaling pathway|coreceptor, insoluble ligand activity involved in frizzled-1 receptor signaling pathway|coreceptor, soluble ligand activity involved in canonical Wnt receptor signaling pathway|coreceptor activity involved in Wnt receptor signalling pathway through beta-catenin|Wnt co-receptor, canonical pathway|coreceptor activity involved in Wnt receptor signaling pathway via beta-catenin|coreceptor, insoluble ligand activity involved in Wnt receptor signaling pathway via beta-catenin|coreceptor activity involved in frizzled-1 receptor signaling pathway|coreceptor, insoluble ligand activity involved in canonical Wnt receptor signaling pathway|coreceptor, insoluble ligand activity involved in canonical Wnt signaling pathway|coreceptor, soluble ligand activity involved in canonical Wnt signaling pathway|coreceptor, soluble ligand activity involved in Wnt receptor signalling pathway through beta-catenin|coreceptor, soluble ligand activity involved in Wnt receptor signaling pathway through beta-catenin|coreceptor activity involved in canonical Wnt-activated signaling pathway|Wnt co-receptor activity, canonical signaling|coreceptor activity involved in Wnt receptor signaling pathway through beta-catenin|coreceptor, insoluble ligand activity involved in Wnt receptor signaling pathway through beta-catenin|coreceptor, soluble ligand activity involved in canonical Wnt-activated signaling pathway|coreceptor, soluble ligand activity involved in Wnt receptor signaling pathway via beta-catenin							bf	2016-01-28T15:14:46Z					molecular_function											owl:Class	
GO:0140232	biolink:NamedThing	intracellular cAMP-activated cation channel activity involved in regulation of presynaptic membrane potential	Enables the transmembrane transfer of a cation by a channel that opens when intracellular cAMP has been bound by the channel complex or one of its constituent parts, to regulate the presynaptic membrane potential.	tmpzr1t_l9r_go_relaxed.owl	intracellular cAMP activated cation channel activity involved in regulation of presynaptic membrane potential	https://github.com/geneontology/synapse/issues/231				Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.		pg	2018-07-09T11:30:40Z					molecular_function											owl:Class	
GO:0097390	biolink:NamedThing	chemokine (C-X-C motif) ligand 12 production	The appearance of chemokine (C-X-C motif) ligand 12 (CXCL12) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	tmpzr1t_l9r_go_relaxed.owl	CXCL12 production							pr	2012-10-23T07:57:28Z					biological_process											owl:Class	
GO:0098616	biolink:NamedThing	selenate adenylyltransferase (ATP) activity	Catalysis of the reaction: ATP + H2SeO4 => diphosphate + adenylylselenate.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-2408525									molecular_function											owl:Class	
GO:0035369	biolink:NamedThing	pre-B cell receptor complex	An immunoglobulin-like complex that is present in at least the plasma membrane of pre-B cells, and that is composed of two identical immunoglobulin heavy chains and two surrogate light chains, each composed of the lambda-5 and VpreB proteins, and a signaling subunit, a heterodimer of the Ig-alpha and Ig-beta proteins.	tmpzr1t_l9r_go_relaxed.owl	pre-BCR					Despite its name, the pre-BCR is not a receptor complex, as it appears to provide a low level of signal not dependent on a ligand, but rather simply on correct assembly of the complex as a measure for correct Ig heavy chain recombination and folding. A significant proportion of pre-BCR complexes fail to reach the cell surface, and in some cases may provide their signaling function from the trans-Golgi network or lysosome.		bf	2010-03-11T10:46:10Z					cellular_component											owl:Class	
GO:1990567	biolink:NamedThing	DPS complex	A protein serine/threonine phosphatase complex that in S. pombe consists of the proteins Dis2, Ppn1, and Swd22.	tmpzr1t_l9r_go_relaxed.owl								al	2014-11-27T09:56:18Z					cellular_component											owl:Class	
GO:1990636	biolink:NamedThing	reproductive senescence	A natural reduction in reproductive capacity with aging, often taking the form of a switch from regular reproductive cycles to irregular and infrequent ones.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-02-10T23:17:56Z					biological_process											owl:Class	
GO:1901084	biolink:NamedThing	pyrrolizidine alkaloid catabolic process	The chemical reactions and pathways resulting in the breakdown of pyrrolizidine alkaloid.	tmpzr1t_l9r_go_relaxed.owl	pyrrolizidine alkaloid catabolism|pyrrolizidine alkaloid breakdown|pyrrolizidine alkaloid degradation							yaf	2012-07-05T10:28:20Z					biological_process											owl:Class	
GO:0016058	biolink:NamedThing	maintenance of membrane potential in photoreceptor cell by rhodopsin mediated signaling	Maintenance of the excited state of a photoreceptor cell to produce a steady-state current as a result of signals generated by rhodopsin activation by a photon.	tmpzr1t_l9r_go_relaxed.owl	maintenance of rhodopsin mediated signalling|maintenance of rhodopsin mediated signaling													biological_process											owl:Class	
GO:0035653	biolink:NamedThing	clathrin-coated vesicle cargo loading, AP-1-mediated	Formation of a macromolecular complex between proteins of the AP-1 adaptor complex and proteins and/or lipoproteins that are going to be transported by a clathrin-coated vesicle. The AP-1 adaptor protein complex is a component of the cytoplasmic coat found on clathrin-coated vesicles, and binds to sorting signals of cargo to facilitate their trafficking.	tmpzr1t_l9r_go_relaxed.owl	cargo loading into clathrin-coated vesicle, AP-1-mediated							bf	2011-01-25T11:01:38Z					biological_process											owl:Class	
GO:0140700	biolink:NamedThing	3',2'-cyclic GMP-AMP synthase activity	Catalysis of the reaction: ATP + GTP = 2 diphosphate + cyclic G-P(3'-5')A-P(2'-5') (cyclic 3',2' GAMP).	tmpzr1t_l9r_go_relaxed.owl	3',2' cyclic-GMP-AMP synthase activity|3',2'-cyclic GAMP synthase activity	https://github.com/geneontology/go-ontology/issues/21980						pg	2021-08-27T05:11:54Z					molecular_function											owl:Class	
GO:0047108	biolink:NamedThing	(R)-3-hydroxyacid-ester dehydrogenase activity	Catalysis of the reaction: ethyl (R)-3-hydroxyhexanoate + NADP(+) = ethyl 3-oxohexanoate + H(+) + NADPH.	tmpzr1t_l9r_go_relaxed.owl	(R)-3-hydroxyacid ester dehydrogenase activity|3-oxo ester (R)-reductase activity|ethyl-(R)-3-hydroxyhexanoate:NADP+ 3-oxidoreductase activity				RHEA:24352|MetaCyc:1.2.1.55-RXN|KEGG_REACTION:R04105|EC:1.1.1.279	Note that this term was EC:1.2.1.55.								molecular_function											owl:Class	
GO:0001571	biolink:NamedThing	non-tyrosine kinase fibroblast growth factor receptor activity	Combining with fibroblast growth factor (FGF) and transmitting the signal from one side of the membrane to the other by a mechanism independent of tyrosine kinase activity.	tmpzr1t_l9r_go_relaxed.owl	non-tyrosine kinase FGF receptor activity|non-tyrosine kinase FGFR activity													molecular_function											owl:Class	
GO:1905316	biolink:NamedThing	superior endocardial cushion morphogenesis	The developmental process by which a superior endocardial cushion is generated and organized.	tmpzr1t_l9r_go_relaxed.owl	dorsal endocardial cushion morphogenesis							rl	2016-07-12T14:08:35Z					biological_process											owl:Class	
GO:0031011	biolink:NamedThing	Ino80 complex	A multisubunit protein complex that contains the Ino80p ATPase; exhibits chromatin remodeling activity.	tmpzr1t_l9r_go_relaxed.owl	INO80 chromatin remodeling complex													cellular_component											owl:Class	
GO:0033062	biolink:NamedThing	Rhp55-Rhp57 complex	A conserved heterodimeric DNA recombinase mediator complex that contains the RecA family proteins Rhp55p and Rph57 in Schizosaccharomyces, or orthologs thereof (e.g. Rad55p and Rad57p in Saccharomyces).	tmpzr1t_l9r_go_relaxed.owl	Rad55-Rad57 complex													cellular_component											owl:Class	
GO:0048166	biolink:NamedThing	mature follicle stage	The stage in oogenesis when the antrum is swollen with follicular fluid. The ovum is ready to erupt from the ovary and is arrested at metaphase of the second meiotic division.	tmpzr1t_l9r_go_relaxed.owl	mammalian oogenesis stage 9													biological_process											owl:Class	
GO:0106286	biolink:NamedThing	(E)-caffeate-CoA ligase activity	Catalysis of the reaction: (E)-caffeate + ATP + CoA = (E)-caffeoyl-CoA + AMP + diphosphate.	tmpzr1t_l9r_go_relaxed.owl					RHEA:36299			hjd	2020-07-30T14:26:08Z					molecular_function											owl:Class	
GO:0018565	biolink:NamedThing	dihydroxydibenzothiophene dioxygenase activity	Catalysis of the reaction: 1,2-dihydroxydibenzothiophene + O2 = cis-4-(2-(3-hydroxy)-thionaphthenyl)-2-oxo-3-butenoate.	tmpzr1t_l9r_go_relaxed.owl					EC:1.13.11.-|UM-BBD_reactionID:r0162									molecular_function											owl:Class	
GO:0070333	biolink:NamedThing	alpha6-beta4 integrin-Shc-Grb2 complex	A protein complex that consists of an alpha6-beta4 integrin complex bound to the adaptor proteins Shc and Grb2.	tmpzr1t_l9r_go_relaxed.owl	ITGA6-ITGB4-SHC-GRB2 complex													cellular_component											owl:Class	
GO:0062173	biolink:NamedThing	brexanolone metabolic process	The chemical reactions and pathways by which living organisms transform brexanolone.	tmpzr1t_l9r_go_relaxed.owl	allotetrahydroprogesterone metabolic process|allotetrahydroprogesterone metabolism|allopregnanolone metabolism|brexanolone metabolism|allopregnanolone metabolic process							dph	2019-11-18T19:42:45Z					biological_process											owl:Class	
GO:0018778	biolink:NamedThing	DL-2 haloacid dehalogenase activity	Catalysis of the reaction: trichloroacetate + 2 H2O = 3 H+ + 3 Cl- + oxalate.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0382|EC:3.8.1.10|MetaCyc:RXN-9150									molecular_function											owl:Class	
GO:0098630	biolink:NamedThing	aggregation of unicellular organisms	The clustering together of unicellular organisms in suspension form aggregates.	tmpzr1t_l9r_go_relaxed.owl	aggregation of single cell organisms													biological_process											owl:Class	
GO:0018222	biolink:NamedThing	peptidyl-L-cysteine methyl disulfide biosynthetic process from peptidyl-cysteine	The modification of peptidyl-cysteine to form peptidyl-L-cysteine methyl disulfide.	tmpzr1t_l9r_go_relaxed.owl	peptidyl-L-cysteine methyl disulfide synthesis from peptidyl-cysteine|peptidyl-L-cysteine methyl disulfide formation from peptidyl-cysteine|peptidyl-L-cysteine methyl disulphide biosynthetic process from peptidyl-cysteine|peptidyl-L-cysteine methyl disulfide anabolism from peptidyl-cysteine|peptidyl-L-cysteine methyl disulphide biosynthesis from peptidyl-cysteine				RESID:AA0101									biological_process											owl:Class	
GO:0033612	biolink:NamedThing	receptor serine/threonine kinase binding	Binding to a receptor that possesses protein serine/threonine kinase activity.	tmpzr1t_l9r_go_relaxed.owl	transmembrane receptor protein serine/threonine kinase ligand binding													molecular_function											owl:Class	
GO:0004938	biolink:NamedThing	alpha2-adrenergic receptor activity	Combining with epinephrine or norepinephrine to initiate a change in cell activity via activation of a G protein, with pharmacological characteristics of alpha2-adrenergic receptors; the activity involves transmitting the signal to the Gi alpha subunit of a heterotrimeric G protein.	tmpzr1t_l9r_go_relaxed.owl	alpha2 adrenoceptor													molecular_function											owl:Class	
GO:0036472	biolink:NamedThing	suppression by virus of host protein-protein interaction	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of interaction between host proteins.	tmpzr1t_l9r_go_relaxed.owl	suppression by virus of host protein interaction|suppression by virus of host protein:protein interaction|suppression by virus of host protein:protein binding|suppression by virus of host protein binding							bf	2014-07-21T11:18:51Z					biological_process											owl:Class	
GO:0045522	biolink:NamedThing	interleukin-26 receptor binding	Binding to an interleukin-26 receptor.	tmpzr1t_l9r_go_relaxed.owl	interleukin-26 receptor ligand|IL-26													molecular_function											owl:Class	
GO:0061953	biolink:NamedThing	mRNA (adenine-N1-)-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + adenine in mRNA = S-adenosyl-L-homocysteine + N(1)-methyladenine in mRNA.	tmpzr1t_l9r_go_relaxed.owl								dph	2017-11-08T13:26:35Z					molecular_function											owl:Class	
GO:0002383	biolink:NamedThing	immune response in brain or nervous system	An immune response taking place in the brain or nervous system.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0071284	biolink:NamedThing	cellular response to lead ion	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lead ion stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-12-10T04:00:41Z					biological_process											owl:Class	
GO:0046441	biolink:NamedThing	D-lysine metabolic process	The chemical reactions and pathways involving D-lysine, the D-enantiomer of lysine; i.e. (2R)-2,6-diaminohexanoic acid.	tmpzr1t_l9r_go_relaxed.owl	D-lysine metabolism													biological_process											owl:Class	
GO:0034873	biolink:NamedThing	thioacetamide S-oxygenase activity	Catalysis of the reaction: thioacetamide + O2 + 2 H+ + 2 e- = thioacetamide S-oxide + H2O.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r1312									molecular_function											owl:Class	
GO:0034317	biolink:NamedThing	nicotinic acid riboside kinase activity	Catalysis of the reaction: ATP + nicotinic acid riboside = ADP + nicotinic acid mononucleotide.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-8443									molecular_function											owl:Class	
GO:0071032	biolink:NamedThing	nuclear mRNA surveillance of mRNP export	The set of processes involved in identifying and degrading incorrectly formed or aberrant nuclear mRNPs docked at the nuclear pore complex prior to export to the cytoplasm.	tmpzr1t_l9r_go_relaxed.owl	nuclear mRNA catabolic process of mRNAs in aberrant mRNPs|nuclear mRNA quality control of mRNAs in aberrant mRNPs							krc	2009-07-28T04:31:57Z					biological_process											owl:Class	
GO:1903544	biolink:NamedThing	response to butyrate	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a butyrate stimulus.	tmpzr1t_l9r_go_relaxed.owl								mr	2014-10-17T13:57:25Z					biological_process											owl:Class	
GO:0070090	biolink:NamedThing	metaphase plate	The intracellular plane, located halfway between the poles of the spindle, where chromosomes align during metaphase of mitotic or meiotic nuclear division.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0042966	biolink:NamedThing	biotin carboxyl carrier protein biosynthetic process	The chemical reactions and pathways resulting in the formation of the biotin carboxyl carrier protein, a subunit of acetyl-coenzyme A carboxylase.	tmpzr1t_l9r_go_relaxed.owl	biotin carboxyl carrier protein synthesis|BCCP biosynthetic process|biotin carboxyl carrier protein formation|biotin carboxyl carrier protein anabolism|BCCP biosynthesis|biotin carboxyl carrier protein biosynthesis													biological_process											owl:Class	
GO:0070721	biolink:NamedThing	ISGF3 complex	A transcription factor complex that consists of a Stat1-Stat2 heterodimer and the IRF9 protein.	tmpzr1t_l9r_go_relaxed.owl	interferon-stimulated gene factor 3 transcription complex							mah	2009-06-10T05:22:05Z					cellular_component											owl:Class	
GO:0019593	biolink:NamedThing	mannitol biosynthetic process	The chemical reactions and pathways resulting in the formation of mannitol, the alditol derived from D-mannose by reduction of the aldehyde group.	tmpzr1t_l9r_go_relaxed.owl	mannitol formation|mannitol synthesis|mannitol biosynthesis|mannitol anabolism				MetaCyc:PWY-3881									biological_process											owl:Class	
GO:0120091	biolink:NamedThing	jasmonic acid hydrolase	Catalyzes the hydroxylation of jasmonic acid to 12OH-jasmonic acid.	tmpzr1t_l9r_go_relaxed.owl	2-oxoglutarate dioxygenase							krc	2017-08-18T23:25:52Z					molecular_function											owl:Class	
GO:0008418	biolink:NamedThing	protein-N-terminal asparagine amidohydrolase activity	Catalysis of the reaction: protein-L-asparagine + H2O = protein-L-aspartate + NH3. This reaction is the deamidation of an N-terminal asparagine residue in a peptide or protein.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0008270	biolink:NamedThing	zinc ion binding	Binding to a zinc ion (Zn).	tmpzr1t_l9r_go_relaxed.owl	zinc binding|Zn binding													molecular_function											owl:Class	
GO:0034737	biolink:NamedThing	ergosterol O-acyltransferase activity	Catalysis of the reaction: acyl-CoA + ergosterol = CoA + ergosterol ester.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0110051	biolink:NamedThing	metabolite repair	A cellular process that, through single- or multi-step enzymatic reactions, repairs useless or toxic endogenous compounds, formed as by-products of primary metabolism, by converting them into useful metabolites.	tmpzr1t_l9r_go_relaxed.owl								kmv	2017-09-08T15:16:01Z					biological_process											owl:Class	
GO:1902984	biolink:NamedThing	pre-replicative complex assembly involved in premeiotic DNA replication	Any pre-replicative complex assembly involved in meiotic cell cycle DNA replication.	tmpzr1t_l9r_go_relaxed.owl	pre-replicative complex assembly involved in meiotic cell cycle DNA replication|pre-replicative complex assembly involved in meiosis|pre-RC complex assembly involved in meiosis|pre-replicative complex formation involved in meiosis|nuclear pre-replicative complex assembly involved in meiotic cell cycle							jl	2014-05-06T20:33:28Z					biological_process											owl:Class	
GO:0035866	biolink:NamedThing	alphav-beta3 integrin-PKCalpha complex	A protein complex that consists of an alphav-beta3 integrin complex bound to protein kinase C alpha.	tmpzr1t_l9r_go_relaxed.owl	alphav-beta3 integrin-PKCa complex|alphav-beta3 integrin-protein kinase C alpha complex							bf	2011-05-25T03:03:59Z					cellular_component											owl:Class	
GO:0004488	biolink:NamedThing	methylenetetrahydrofolate dehydrogenase (NADP+) activity	Catalysis of the reaction: 5,10-methylenetetrahydrofolate + NADP(+) = 5,10-methenyltetrahydrofolate + NADPH.	tmpzr1t_l9r_go_relaxed.owl	5,10-methylenetetrahydrofolate:NADP+ oxidoreductase activity|5,10-methylenetetrahydrofolate:NADP oxidoreductase activity				RHEA:22812|KEGG_REACTION:R01220|EC:1.5.1.5|MetaCyc:METHYLENETHFDEHYDROG-NADP-RXN									molecular_function											owl:Class	
GO:0004486	biolink:NamedThing	methylenetetrahydrofolate dehydrogenase [NAD(P)+] activity	Catalysis of the reaction: 5,10-methylenetetrahydrofolate + NAD(P)+ = 5,10-methenyltetrahydrofolate + NAD(P)H + H+.	tmpzr1t_l9r_go_relaxed.owl	5,10-methylene-THF dehydrogenase activity|N5,N10-methylenetetrahydrofolate dehydrogenase activity				Reactome:R-HSA-200644|Reactome:R-HSA-200718|EC:1.5.1.5									molecular_function											owl:Class	
GO:0036122	biolink:NamedThing	BMP binding	Binding to a member of the bone morphogenetic protein (BMP) family.	tmpzr1t_l9r_go_relaxed.owl	bone morphogenetic protein binding							bf	2012-02-20T02:59:34Z					molecular_function											owl:Class	
GO:1990338	biolink:NamedThing	laminin-14 complex	A laminin complex composed of alpha4, beta2 and gamma3 polypeptide chains.	tmpzr1t_l9r_go_relaxed.owl	laminin-423							bhm	2014-03-20T23:37:11Z					cellular_component											owl:Class	
GO:0047353	biolink:NamedThing	N-methylphosphoethanolamine cytidylyltransferase activity	Catalysis of the reaction: N-methylethanolamine phosphate + CTP = CDP-N-methylethanolamine + diphosphate.	tmpzr1t_l9r_go_relaxed.owl	monomethylethanolamine phosphate cytidylyltransferase activity|CTP:N-methylphosphoethanolamine cytidylyltransferase activity|CTP:P-MEA cytidylyltransferase activity|CTP:N-methylethanolamine-phosphate cytidylyltransferase activity				MetaCyc:2.7.7.57-RXN|EC:2.7.7.57|RHEA:10576|KEGG_REACTION:R03375									molecular_function											owl:Class	
GO:0047202	biolink:NamedThing	sinapoylglucose-choline O-sinapoyltransferase activity	Catalysis of the reaction: 1-O-sinapoyl-beta-D-glucose + choline = O-sinapoylcholine + D-glucose.	tmpzr1t_l9r_go_relaxed.owl	sinapine synthase activity|1-O-(4-hydroxy-3,5-dimethoxycinnamoyl)-beta-D-glucose:choline 1-O-(4-hydroxy-3,5-dimethoxycinnamoyl)transferase activity				MetaCyc:2.3.1.91-RXN|RHEA:12024|KEGG_REACTION:R03075|EC:2.3.1.91									molecular_function											owl:Class	
GO:0071116	biolink:NamedThing	alpha6-beta1 integrin-CYR61 complex	A protein complex that consists of an alpha6-beta1 integrin complex bound to CYR61, a cysteine-rich protein involved in angiogenesis.	tmpzr1t_l9r_go_relaxed.owl	ITGA6-ITGB1-CYR61 complex							mah	2009-11-13T02:19:23Z					cellular_component											owl:Class	
GO:0047638	biolink:NamedThing	albendazole monooxygenase activity	Catalysis of the reaction: albendazole + H(+) + NADPH + O(2) = albendazole S-oxide + H(2)O + NADP(+).	tmpzr1t_l9r_go_relaxed.owl	albendazole sulfoxidase activity|albendazole oxidase activity|albendazole,NADPH:oxygen oxidoreductase (sulfoxide-forming)				EC:1.14.13.32|KEGG_REACTION:R03712|RHEA:10796|MetaCyc:ALBENDAZOLE-MONOOXYGENASE-RXN									molecular_function											owl:Class	
GO:0008815	biolink:NamedThing	citrate (pro-3S)-lyase activity	Catalysis of the reaction: citrate = acetate + oxaloacetate.	tmpzr1t_l9r_go_relaxed.owl	citrate aldolase activity|citritase activity|citrate lyase activity|citridesmolase activity|citric aldolase activity|citrate oxaloacetate-lyase [(pro-3S)-CH2COO-->acetate]|citratase activity|citrate lyase|citrate oxaloacetate-lyase activity|citrase activity				KEGG_REACTION:R00362|EC:4.1.3.6|RHEA:10760|MetaCyc:CITLY-RXN									molecular_function											owl:Class	
GO:0047258	biolink:NamedThing	sphingosine beta-galactosyltransferase activity	Catalysis of the reaction: sphingosine + UDP-D-galactose = H(+) + psychosine + UDP.	tmpzr1t_l9r_go_relaxed.owl	psychosine-UDP galactosyltransferase activity|UDPgalactose:sphingosine 1-beta-galactotransferase activity|psychosine-uridine diphosphate galactosyltransferase activity|UDP-galactose:sphingosine 1-beta-galactotransferase activity|galactosyl-sphingosine transferase activity|UDPgalactose:sphingosine O-galactosyl transferase activity|uridine diphosphogalactose-sphingosine beta-galactosyltransferase activity				RHEA:19485|KEGG_REACTION:R01928|MetaCyc:2.4.1.23-RXN|EC:2.4.1.23									molecular_function											owl:Class	
GO:0050245	biolink:NamedThing	quercitrinase activity	Catalysis of the reaction: H(2)O + quercitrin = L-rhamnose + quercetin.	tmpzr1t_l9r_go_relaxed.owl	quercitrin 3-L-rhamnohydrolase activity				KEGG_REACTION:R02436|MetaCyc:QUERCITRINASE-RXN|RHEA:17465|EC:3.2.1.66									molecular_function											owl:Class	
GO:0034851	biolink:NamedThing	2,4,4-trimethyl-3-oxopentanoyl-CoA 2-C-propanoyl transferase activity	Catalysis of the reaction: 2,4,4-trimethyl-3-oxopentanoyl-CoA + CoASH = pivalyl-CoA + propanoyl-CoA.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r1274									molecular_function											owl:Class	
GO:0047994	biolink:NamedThing	hydroxymethylglutaryl-CoA hydrolase activity	Catalysis of the reaction: (S)-3-hydroxy-3-methylglutaryl-CoA + H(2)O = 3-hydroxy-3-methylglutarate + CoA + H(+).	tmpzr1t_l9r_go_relaxed.owl	hydroxymethylglutaryl coenzyme A deacylase activity|hydroxymethylglutaryl coenzyme A hydrolase activity|3-hydroxy-3-methylglutaryl-CoA hydrolase activity|(S)-3-hydroxy-3-methylglutaryl-CoA hydrolase activity|beta-hydroxy-beta-methylglutaryl coenzyme A hydrolase activity|beta-hydroxy-beta-methylglutaryl coenzyme A deacylase activity				RHEA:16305|EC:3.1.2.5|MetaCyc:HYDROXYMETHYLGLUTARYL-COA-HYDROLASE-RXN|KEGG_REACTION:R02083									molecular_function											owl:Class	
GO:0072166	biolink:NamedThing	posterior mesonephric tubule development	The progression of the posterior mesonephric tubule over time, from its initial formation to the mature structure. The posterior mesonephric tubule is an epithelial tube that is part of the mesonephros.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-02-26T01:47:50Z					biological_process											owl:Class	
GO:0051334	biolink:NamedThing	meiosis I nuclear membrane reassembly	The reformation of the nuclear membranes during meiosis I.	tmpzr1t_l9r_go_relaxed.owl	meiosis I nuclear envelope reassembly	https://github.com/geneontology/go-ontology/issues/20636												biological_process											owl:Class	
GO:0071518	biolink:NamedThing	autoinducer-2 kinase activity	Catalysis of the reaction: 4,5-dihydroxy-pentane-2,3-dione + ATP = 5-phospho-4-hydroxy-pentane-2,3-dione (P-DPD) + ADP.	tmpzr1t_l9r_go_relaxed.owl	4,5-dihydroxy-pentane-2,3-dione kinase activity				MetaCyc:RXN0-5461|RHEA:15377			mah	2010-01-06T05:08:17Z					molecular_function											owl:Class	
GO:1990467	biolink:NamedThing	NuA3a histone acetyltransferase complex	A NuA3 complex that catalyzes the acetylation of Histone H3. In S. cerevisiae, this complex consists of Eaf6p, Nto1p, Sas3p, Taf14p, Yng1p and associates with H3K4me3 using Yng1p.	tmpzr1t_l9r_go_relaxed.owl								rb	2014-08-25T23:07:45Z					cellular_component											owl:Class	
GO:1904784	biolink:NamedThing	NLRP1 inflammasome complex assembly	The aggregation, arrangement and bonding together of a set of components to form a NLRP1 inflammasome complex.	tmpzr1t_l9r_go_relaxed.owl	NALP1 inflammasome complex assembly|NALP1 inflammasome complex formation|NLRP1 inflammasome complex formation	https://github.com/geneontology/go-ontology/issues/21092				The aggregation, arrangement and bonding together of a set of components to form the NLRP1 inflammasome complex, occurring at the level of an individual cell.		ae	2015-11-02T09:39:44Z					biological_process											owl:Class	
GO:0016689	biolink:NamedThing	manganese peroxidase activity	Catalysis of the reaction: 2 Mn2+ + 2 H+ + hydrogen peroxide = 2 Mn3+ + 2 H2O.	tmpzr1t_l9r_go_relaxed.owl	Mn-dependent (NADH-oxidizing) peroxidase activity|Mn-dependent peroxidase activity|Mn(II):hydrogen-peroxide oxidoreductase activity|peroxidase-M2				RHEA:22776|EC:1.11.1.13|MetaCyc:MANGANESE-PEROXIDASE-RXN									molecular_function											owl:Class	
GO:0031588	biolink:NamedThing	nucleotide-activated protein kinase complex	A protein complex that possesses nucleotide-dependent protein kinase activity. The nucleotide can be AMP (in S. pombe and human) or ADP (in S. cerevisiae).	tmpzr1t_l9r_go_relaxed.owl	Snf1 kinase complex|ADP-activated protein kinase complex|SNF1/AMPK protein kinase complex|5'-AMP-activated protein kinase complex|AMPK complex|Snf1 serine/threonine protein kinase complex|AMP-activated protein kinase complex													cellular_component											owl:Class	
GO:0002172	biolink:NamedThing	high-affinity IgM receptor activity	Combining with high affinity with an immunoglobulin of an IgM isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	high affinity IgM receptor activity							hjd	2010-05-06T05:03:26Z					molecular_function											owl:Class	
GO:0050311	biolink:NamedThing	sulfite reductase (ferredoxin) activity	Catalysis of the reaction: hydrogen sulfide + 3 oxidized ferredoxin + 3 H2O = sulfite + 3 reduced ferredoxin.	tmpzr1t_l9r_go_relaxed.owl	sulphite reductase (ferredoxin) activity|ferredoxin-sulfite reductase activity|hydrogen-sulfide:ferredoxin oxidoreductase activity				MetaCyc:SULFITE-REDUCTASE-FERREDOXIN-RXN|EC:1.8.7.1|RHEA:23132									molecular_function											owl:Class	
GO:0102135	biolink:NamedThing	(22S)-22-hydroxy-campest-4-en-3-one C-23 hydroxylase activity	Catalysis of the reaction: H+ + (22S)-22-hydroxycampest-4-en-3-one + NADPH + O2 <=> (22R,23R)-22,23-dihydroxy-campest-4-en-3-one + NADP + H2O.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-11530									molecular_function											owl:Class	
GO:0102543	biolink:NamedThing	epsilon-rhodomycinone methylesterase activity	Catalysis of the reaction: epsilon-rhodomycinone + H2O <=> 15-demethoxy-epsilon-rhodomycinone + methanol + H+.	tmpzr1t_l9r_go_relaxed.owl					EC:3.1.1.95|MetaCyc:RXN-14865									molecular_function											owl:Class	
GO:0043885	biolink:NamedThing	carbon-monoxide dehydrogenase (ferredoxin) activity	Catalysis of the reaction: CO + H2O + oxidized ferredoxin = CO2 + reduced ferredoxin.	tmpzr1t_l9r_go_relaxed.owl	CO-dehydrogenase (ferredoxin) activity|carbon-monoxide:(acceptor) oxidoreductase activity|carbon-monoxide dehydrogenase activity|CO-dehydrogenase activity|carbon monoxide dehydrogenase activity|CODH|CO dehydrogenase activity|carbon monoxide dehydrogenase (ferredoxin) activity|carbon-monoxide,water:ferredoxin oxidoreductase activity				MetaCyc:CARBON-MONOXIDE-DEHYDROGENASE-RXN|EC:1.2.7.4									molecular_function											owl:Class	
GO:0097661	biolink:NamedThing	SCF-Ctf13 ubiquitin ligase complex	An SCF ubiquitin ligase complex in which the F-box protein is Ctf13 in S. cerevisiae.	tmpzr1t_l9r_go_relaxed.owl								pr	2014-10-06T10:25:56Z					cellular_component											owl:Class	
GO:0036148	biolink:NamedThing	phosphatidylglycerol acyl-chain remodeling	Remodeling the acyl chains of phosphatidylglycerol, through sequential deacylation and re-acylation reactions, to generate phosphatidylglycerol containing different types of fatty acid acyl chains.	tmpzr1t_l9r_go_relaxed.owl								bf	2012-03-14T01:14:23Z					biological_process											owl:Class	
GO:0090719	biolink:NamedThing	adaptive immune effector response involving T cells and B lineage cells	An adaptive immune effector response involving T cells and B lineage cells. In the case of B lineage cells, the effector cells are the antibody secreting plasma cells whereas for T cells the effector cells may be helper T cells or cytotoxic T cells.	tmpzr1t_l9r_go_relaxed.owl								tb	2016-11-11T12:43:26Z					biological_process											owl:Class	
GO:0046754	biolink:NamedThing	viral exocytosis	The exit of enveloped or unenveloped virion particles from the host cell by exocytosis, without causing cell lysis.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0070031	biolink:NamedThing	alphav-beta5 integrin-osteopontin complex	A protein complex that consists of an alphav-beta5 integrin complex bound to osteopontin.	tmpzr1t_l9r_go_relaxed.owl	ITGAV-ITGB5-SPP1 complex													cellular_component											owl:Class	
GO:0070636	biolink:NamedThing	nicotinic acid riboside hydrolase activity	Catalysis of the reaction: nicotinic acid riboside + H2O = nicotinic acid + D-ribose.	tmpzr1t_l9r_go_relaxed.owl	nicotinate ribonucleoside hydrolase activity|D-ribosylnicotinate hydrolase activity|D-ribosylnicotinic acid hydrolase activity|nicotinate riboside hydrolase activity|nicotinic acid ribonucleoside hydrolase activity							mah	2009-05-07T02:12:00Z					molecular_function											owl:Class	
GO:0036133	biolink:NamedThing	11-hydroxythromboxane B2 dehydrogenase activity	Catalysis of the reaction: thromboxane B2 + NAD+ = 11-dehydro-thromboxane B2 + NADH + H+.	tmpzr1t_l9r_go_relaxed.owl	NAD dependent 11-hydroxythromboxane B2 dehydrogenase activity				RHEA:52312|KEGG_REACTION:R05060|Reactome:R-HSA-2161732	Note that the KEGG_REACTION:R05060 reaction does not stipulate the acceptor group, and is therefore slightly more general than the activity described by GO:0036133.		bf	2012-03-05T11:05:09Z					molecular_function											owl:Class	
GO:0016438	biolink:NamedThing	tRNA-queuosine beta-mannosyltransferase activity	Catalysis of the reaction: GDP-mannose + tRNA(Asp)-queuosine = GDP + tRNA(Asp)-O-5''-beta-D-mannosylqueuosine.	tmpzr1t_l9r_go_relaxed.owl	GDP-mannose:tRNAAsp-queuosine O-5''-beta-D-mannosyltransferase activity				RHEA:12885|EC:2.4.1.110|MetaCyc:2.4.1.110-RXN									molecular_function											owl:Class	
GO:0043696	biolink:NamedThing	dedifferentiation	The process in which a specialized structure (cell, tissue or organ) loses structural or functional features that characterize it in the mature organism, or some other relatively stable phase of the organism's life history. Under certain conditions, these structures can revert back to the features of their ancestors.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Cellular_differentiation#Dedifferentiation									biological_process											owl:Class	
GO:0048163	biolink:NamedThing	scattered antral spaces stage	The stage in oogenesis when antral spaces begin to form in the follicle cells. Mitochondria form centers for yolk concentration.	tmpzr1t_l9r_go_relaxed.owl	mammalian oogenesis stage 6													biological_process											owl:Class	
GO:1903213	biolink:NamedThing	protein localization to subtelomeric heterochromatin	A process in which a protein is transported to, or maintained in, a location within a subtelomeric heterochromatin.	tmpzr1t_l9r_go_relaxed.owl	protein localisation in subtelomeric heterochromatin|protein localisation to subtelomeric heterochromatin|protein localization in subtelomeric heterochromatin|protein localisation to telomeric heterochromatin|protein localization to telomeric heterochromatin							mah	2013-07-31T15:04:26Z			GO:1990152		biological_process											owl:Class	
GO:1990726	biolink:NamedThing	Lsm1-7-Pat1 complex	A conserved, heteroheptameric, cytoplasmic protein complex composed of Lsm1, Lsm2, Lsm3, Lsm4, Lsm5, Lsm6, Lsm7, and Pat1, or orthologs thereof, that shows a strong binding preference for oligoadenylated RNAs over polyadenylated RNAs. May bind further associated proteins. Facilitates the deadenylation-dependent decapping of mRNA in the P-body thereby regulating mRNA decay and subsequent degradation by the 5' to 3' pathway.	tmpzr1t_l9r_go_relaxed.owl								pr	2015-04-08T09:22:36Z					cellular_component											owl:Class	
GO:0005080	biolink:NamedThing	protein kinase C binding	Binding to protein kinase C.	tmpzr1t_l9r_go_relaxed.owl	PKC binding|protein kinase C alpha binding|protein kinase C delta binding|PKC eta binding|PKC alpha binding|PKC delta binding|protein kinase C eta binding											GO:0072569|GO:0072568|GO:0097024		molecular_function											owl:Class	
GO:0070126	biolink:NamedThing	mitochondrial translational termination	The process resulting in the release of a polypeptide chain from the ribosome in a mitochondrion, usually in response to a termination codon (note that mitochondria use variants of the universal genetic code that differ between different taxa).	tmpzr1t_l9r_go_relaxed.owl	mitochondrial translation termination													biological_process											owl:Class	
GO:0018392	biolink:NamedThing	glycoprotein 3-alpha-L-fucosyltransferase activity	Catalysis of the reaction: N(4)-{N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->6)]-beta-D-mannosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl}-L-asparagine + GDP-L-fucose = N(4)-{N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->6)]-beta-D-mannosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-[alpha-L-fucosyl-(1->3)]-N-acetyl-beta-D-glucosaminyl}-L-asparagine + GDP + H(+).	tmpzr1t_l9r_go_relaxed.owl	GDP-L-fucose:glycoprotein (L-fucose to asparagine-linked N-acetylglucosamine of 4-N-{N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->6)]-beta-D-mannosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl}asparagine) 3-alpha-L-fucosyl-transferase activity|GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha1,3-fucosyltransferase activity|GDP-fucose:beta-N-acetylglucosamine (Fuc to (Fuc-alpha-1->6-GlcNAc)-Asn-peptide) alpha-1->3-fucosyltransferase activity|GDP-fucose:beta-N-acetylglucosamine (Fuc to (Fucalpha1->6GlcNAc)-Asn-peptide) alpha1->3-fucosyltransferase activity|GDP-L-Fuc:Asn-linked GlcNAc alpha-1,3-fucosyltransferase activity|GDP-L-fucose:glycoprotein (L-fucose to asparagine-linked N-acetylglucosamine of N4-{N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->6)]-beta-D-mannosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl}asparagine) 3-alpha-L-fucosyl-transferase activity|GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha-1,3-fucosyltransferase activity|GDP-L-fucose:asparagine-linked N-acetylglucosamine alpha(1,3)-fucosyltransferase activity|GDP-L-Fuc:Asn-linked GlcNAc alpha1,3-fucosyltransferase activity|GDP-fucose:beta-N-acetylglucosamine (Fuc to (Fucalpha1->6-GlcNAc)-Asn-peptide) alpha1->3-fucosyltransferase activity				EC:2.4.1.214|KEGG_REACTION:R06015|MetaCyc:2.4.1.214-RXN|RHEA:24444									molecular_function											owl:Class	
GO:0035748	biolink:NamedThing	myelin sheath abaxonal region	The region of the myelin sheath furthest from the axon.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-03-23T10:16:14Z					cellular_component											owl:Class	
GO:0006187	biolink:NamedThing	dGTP biosynthetic process from dGDP	The chemical reactions and pathways resulting in the formation of dGTP, deoxyguanosine triphosphate (2'-deoxyguanosine 5'-triphosphate) from other compounds, including gGDP, deoxyguanosine diphosphate.	tmpzr1t_l9r_go_relaxed.owl	dGTP formation from dGDP|dGTP synthesis from dGDP|dGTP anabolism from dGDP													biological_process											owl:Class	
GO:0110076	biolink:NamedThing	negative regulation of ferroptosis	Any process that stops, prevents, or reduces the frequency, rate or extent of ferroptosis.	tmpzr1t_l9r_go_relaxed.owl								kmv	2018-01-11T18:00:05Z					biological_process											owl:Class	
GO:1990963	biolink:NamedThing	establishment of blood-retinal barrier	Establishment of the barrier between the blood and the retina. The blood-retinal barrier is located at two levels, forming an outer barrier in the retinal pigment epithelium and an inner barrier in the endothelial membrane of the retinal vessels. Both these membranes have tight junctions of the 'nonleaky' type.	tmpzr1t_l9r_go_relaxed.owl	establishment of BRB|establishment of blood-retina barrier							sl	2016-06-07T21:17:55Z					biological_process											owl:Class	
GO:0060006	biolink:NamedThing	angular vestibuloocular reflex	A vestibular reflex by which a response to an angular acceleration stimulus begins with an afferent nerve impulse from a receptor in the semi-circular canal and ends with the compensatory action of eye muscles. Signaling never reaches a level of consciousness.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0016018	biolink:NamedThing	cyclosporin A binding	Binding to cyclosporin A, a cyclic undecapeptide that contains several N-methylated and unusual amino acids.	tmpzr1t_l9r_go_relaxed.owl	cyclophilin													molecular_function											owl:Class	
GO:0102573	biolink:NamedThing	aminodeoxyfutalosine synthase activity	Catalysis of the reaction: 3-[(1-carboxylatovinyl)oxy]benzoate(2-) + S-adenosyl-L-methionine  + H2O <=> aminodeoxyfutalosinate + L-methionine  + hydrogencarbonate + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-15264|RHEA:33075|EC:2.5.1.120									molecular_function											owl:Class	
GO:0035001	biolink:NamedThing	dorsal trunk growth, open tracheal system	Growth of epithelial tubes that originate from pits in an open tracheal system and grow towards each other to meet and form a continuous open tube called the dorsal trunk. The dorsal trunk extends from the anterior spiracle to the posterior spiracle of the larva and forms the main airway of the insect tracheal system.	tmpzr1t_l9r_go_relaxed.owl	dorsal trunk growth													biological_process											owl:Class	
GO:1904176	biolink:NamedThing	carbon phosphorus lyase complex	A protein complex which is capable of carbon phosphorus lyase activity.	tmpzr1t_l9r_go_relaxed.owl						An example of this is PhnJ in E. coli (P16688) in PMID:22089136 (inferred from direct assay).		bhm	2015-04-29T08:17:13Z					cellular_component											owl:Class	
GO:0047500	biolink:NamedThing	(+)-borneol dehydrogenase activity	Catalysis of the reaction: (+)-borneol + NAD(+) = (1R, 4R)-camphor + H(+) + NADH.	tmpzr1t_l9r_go_relaxed.owl	(+)-borneol:NAD+ oxidoreductase activity|bicyclic monoterpenol dehydrogenase activity				RHEA:17329|KEGG_REACTION:R02944|EC:1.1.1.198|MetaCyc:+-BORNEOL-DEHYDROGENASE-RXN									molecular_function											owl:Class	
GO:0097717	biolink:NamedThing	copper ion transport across blood-cerebrospinal fluid barrier	The directed movement of copper (Cu) ions passing through the blood-cerebrospinal fluid barrier.	tmpzr1t_l9r_go_relaxed.owl	copper ion transport across blood/CSF barrier|copper ion transport across BCB|copper ion transport across BCSFB|copper ion transport across blood/cerebrospinal fluid barrier|copper ion transport across blood-CSF barrier							pr	2016-08-23T14:37:33Z					biological_process											owl:Class	
GO:0018775	biolink:NamedThing	2-hydroxymuconate-semialdehyde hydrolase activity	Catalysis of the reaction: 2-hydroxymuconate semialdehyde + H2O = formate + 2-oxopent-4-enoate.	tmpzr1t_l9r_go_relaxed.owl	2-hydroxymuconate-semialdehyde formylhydrolase activity|HOD hydrolase activity|2-hydroxymuconic semialdehyde hydrolase activity|HMSH				MetaCyc:3.7.1.9-RXN|EC:3.7.1.9|RHEA:14549|UM-BBD_enzymeID:e0139									molecular_function											owl:Class	
GO:0033412	biolink:NamedThing	UAG codon-amino acid adaptor activity	A triplet codon-amino acid adaptor activity that recognizes a UAG codon.	tmpzr1t_l9r_go_relaxed.owl	TAG codon-amino acid adaptor activity					Note that in the standard genetic code, TAG is a stop codon (amber) and is not normally read by a tRNA.								molecular_function											owl:Class	
GO:0031992	biolink:NamedThing	energy transducer activity	The biological transducer activity that accepts energy and converts it to another form, often by transfer to another molecule within the cell.	tmpzr1t_l9r_go_relaxed.owl	photon capture|light harvesting activity													molecular_function											owl:Class	
GO:0043732	biolink:NamedThing	6-hydroxynicotinate dehydrogenase activity	Catalysis of the reaction: 6-hydroxynicotinate + H(2)O + O(2) = 2,6-dihydroxynicotinate + H(2)O(2).	tmpzr1t_l9r_go_relaxed.owl	6-hydroxynicotinic acid dehydrogenase activity|6-hydroxynicotinic acid hydroxylase activity|6-hydroxynicotinate hydroxylase activity|6-hydroxynicotinate:O2 oxidoreductase activity				KEGG_REACTION:R07221|RHEA:22808|MetaCyc:RXN-7585|EC:1.17.3.3									molecular_function											owl:Class	
GO:0090573	biolink:NamedThing	RNA polymerase IV transcription repressor complex	A protein complex, located in the nucleus, that possesses activity that prevents or downregulates transcription from a RNA polymerase IV promoter.	tmpzr1t_l9r_go_relaxed.owl								tb	2014-05-09T13:26:16Z					cellular_component											owl:Class	
GO:0062153	biolink:NamedThing	C5-methylcytidine-containing RNA binding	Binding to an RNA molecule modified by C5-methylcytidine.	tmpzr1t_l9r_go_relaxed.owl	C5-methylcytosine-containing RNA binding							dph	2019-09-18T14:46:22Z					molecular_function											owl:Class	
GO:0030110	biolink:NamedThing	HLA-C specific inhibitory MHC class I receptor activity	Combining with a MHC class I molecule of the HLA-C subclass to mediate signaling that inhibits activation of a lymphocyte.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1905540	biolink:NamedThing	interleukin-7 receptor complex	A protein complex that binds interleukin-7 (IL-7) and that consists of, at a minimum, an interleukin, an alpha and a gamma chain as well as optional additional kinase subunits. The alpha chain binds IL-7 with high affinity and subsequently binds the cytokine receptor common gamma chain that forms part of multiple interleukin receptors.	tmpzr1t_l9r_go_relaxed.owl	IL7 receptor complex|IL-7 receptor complex|IL7-receptor complex|IL-7-receptor complex					An example of this is IL7R in human (P16871) in PMID:19141282 (inferred from direct assay).		bhm	2016-10-10T07:44:05Z					cellular_component											owl:Class	
GO:0038185	biolink:NamedThing	intracellular bile acid receptor signaling pathway	A series of molecular signals initiated by a bile acid binding to an receptor located within a cell, and ending with regulation of a downstream cellular process, e.g. transcription.	tmpzr1t_l9r_go_relaxed.owl	nuclear bile acid receptor signaling pathway							bf	2013-05-16T11:08:02Z					biological_process											owl:Class	
GO:0009024	biolink:NamedThing	tagatose-6-phosphate kinase activity	Catalysis of the reaction: ATP + D-tagatose 6-phosphate = ADP + D-tagatose 1,6-bisphosphate.	tmpzr1t_l9r_go_relaxed.owl	ATP:D-tagatose-6-phosphate 1-phosphotransferase activity|phosphotagatokinase activity				MetaCyc:TAGAKIN-RXN|EC:2.7.1.144|RHEA:12420									molecular_function											owl:Class	
GO:0016152	biolink:NamedThing	mercury (II) reductase activity	Catalysis of the reaction: H(+) + Hg + NADP(+) = Hg(2+) + NADPH.	tmpzr1t_l9r_go_relaxed.owl	mercurate(II) reductase activity|Hg:NADP+ oxidoreductase activity|reduced NADP:mercuric ion oxidoreductase activity|mer A|mercury reductase activity|mercury(II) reductase activity|mercuric ion reductase activity|mercuric reductase activity				KEGG_REACTION:R02807|UM-BBD_reactionID:r0406|MetaCyc:MERCURY-II-REDUCTASE-RXN|RHEA:23856|EC:1.16.1.1							GO:0018692		molecular_function											owl:Class	
GO:1990662	biolink:NamedThing	S100A9 complex	A protein complex composed of a S100A9 dimer and capable of binding to toll-like receptor 4 (TLR4) and the receptor for advanced glycation end products (RAGE) initiating signal transduction through NF-kappa-B pathways. Transports arachidonic acid between the cytosol and the NADPH oxidase complex at the plasma membrane in neutrophils as part of an inflammatory signal cascade leading to an oxidative burst. Complexes with microtubules to increase cell motility.	tmpzr1t_l9r_go_relaxed.owl	S100A9 homodimer					An example of this is S100A9 in human (UniProt symbol P06702) in PMID:15642721 (inferred from direct assay).		bhm	2015-02-25T15:55:48Z					cellular_component											owl:Class	
GO:1901703	biolink:NamedThing	protein localization involved in auxin polar transport	Any protein localization that is involved in auxin polar transport.	tmpzr1t_l9r_go_relaxed.owl	protein localisation involved in auxin polar transport|establishment and maintenance of protein localization involved in auxin polar transport							tb	2012-12-13T19:06:13Z					biological_process											owl:Class	
GO:0033874	biolink:NamedThing	scymnol sulfotransferase activity	Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + 5beta-scymnol = 5beta-scymnol sulfate + adenosine 3',5'-diphosphate + H(+).	tmpzr1t_l9r_go_relaxed.owl					KEGG_REACTION:R07798|RHEA:15477|EC:2.8.2.32|MetaCyc:2.8.2.32-RXN									molecular_function											owl:Class	
GO:0038038	biolink:NamedThing	G protein-coupled receptor homodimeric complex	A protein complex that contains two G protein-coupled receptors (GPCRs) of the same subtype. Formation of a GPCR homodimer may be important for the transport of newly formed receptors to the cell surface, and the function of the receptor.	tmpzr1t_l9r_go_relaxed.owl	GPCR homodimer|G-protein coupled receptor homodimer|G-protein coupled receptor homodimeric complex							bf	2011-11-02T04:43:53Z					cellular_component											owl:Class	
GO:0051841	biolink:NamedThing	positive regulation by host of cytolysis of symbiont cells	Any process in which an organism activates or increases the frequency, rate or extent of cytolysis by that organism of cells in its symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	up regulation by host of cytolysis of symbiont cells|stimulation by host of cytolysis of symbiont cells|up-regulation by host of cytolysis of symbiont cells|activation by host of cytolysis of symbiont cells|upregulation by host of cytolysis of symbiont cells													biological_process											owl:Class	
GO:0035225	biolink:NamedThing	determination of genital disc primordium	Allocation of embryonic cells to the genital imaginal disc founder populations. Early in development at the blastoderm stage, the anlage of the genital disc of both sexes consists of three primordia: the female genital primoridum lcoated anteriorly, the anal primoridum located posteriorly, and the male gential primordium between the two.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0015044	biolink:NamedThing	rubredoxin-NAD+ reductase activity	Catalysis of the reaction: reduced rubredoxin + NAD+ = oxidized rubredoxin + NADH + H+.	tmpzr1t_l9r_go_relaxed.owl	rubredoxin--nicotinamide adenine dinucleotide reductase activity|DPNH-rubredoxin reductase activity|NADH--rubredoxin reductase activity|NADH:rubredoxin oxidoreductase activity|rubredoxin:NAD+ oxidoreductase activity|NADH:rubredoxin reductase activity|NADH--rubredoxin oxidoreductase activity|reduced nicotinamide adenine dinucleotide--rubredoxin reductase activity|dihydronicotinamide adenine dinucleotide--rubredoxin reductase activity|rubredoxin--NAD reductase activity				RHEA:18597|MetaCyc:RUBREDOXIN--NAD+-REDUCTASE-RXN|EC:1.18.1.1									molecular_function											owl:Class	
GO:0018732	biolink:NamedThing	sulfolactone hydrolase activity	Catalysis of the reaction: 4-sulfolactone + OH- = HSO3(-) + maleylacetate.	tmpzr1t_l9r_go_relaxed.owl	sulpholactone hydrolase activity				EC:3.1.1.92|UM-BBD_reactionID:r0583									molecular_function											owl:Class	
GO:0106046	biolink:NamedThing	guanine deglycation, glyoxal removal	The removal of glyoxal from a glycated guanine, to form glycolate and a deglycated guanine.	tmpzr1t_l9r_go_relaxed.owl								hjd	2017-08-01T18:19:30Z					biological_process											owl:Class	
GO:0140460	biolink:NamedThing	response to Gram-negative bacterium	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a Gram-negative bacterium.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/19278						pg	2020-04-30T07:34:38Z					biological_process											owl:Class	
GO:0016972	biolink:NamedThing	thiol oxidase activity	Catalysis of the reaction: 4 R'C(R)SH + O2 = 2 R'C(R)S-S(R)CR' + 2 H2O2.	tmpzr1t_l9r_go_relaxed.owl	thiol:oxygen oxidoreductase activity|sulfhydryl oxidase activity				UM-BBD_reactionID:r1293|MetaCyc:THIOL-OXIDASE-RXN|EC:1.8.3.2|RHEA:17357									molecular_function											owl:Class	
GO:0060747	biolink:NamedThing	oral incubation	A parental behavior in which fertilized eggs are taken into the mouth and held until hatching.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-06-22T09:08:58Z					biological_process											owl:Class	
GO:0070524	biolink:NamedThing	11-beta-hydroxysteroid dehydrogenase (NADP+) activity	Catalysis of the reaction: an 11-beta-hydroxysteroid + NADP+ = an 11-oxosteroid + NADPH + H+.	tmpzr1t_l9r_go_relaxed.owl	corticosteroid 11-beta-dehydrogenase activity|beta-hydroxysteroid dehydrogenase				RHEA:11388|EC:1.1.1.146|Wikipedia:11beta-hydroxysteroid_dehydrogenase									molecular_function											owl:Class	
GO:0102580	biolink:NamedThing	cyanidin 3-O-glucoside 2-O''-xylosyltransferase activity	Catalysis of the reaction: cyanidin 3-O-beta-D-glucoside betaine + UDP-alpha-D-xylose <=> cyanidin 3-O-beta-D-sambubioside + UDP.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-15326|EC:2.4.2.51|RHEA:35443									molecular_function											owl:Class	
GO:0047487	biolink:NamedThing	oligogalacturonide lyase activity	Catalysis of the reaction: 4-(4-deoxy-alpha-D-gluc-4-enuronosyl)-D-galacturonate = 2 5-dehydro-4-deoxy-D-glucuronate.	tmpzr1t_l9r_go_relaxed.owl	oligogalacturonate lyase activity|OGTE|unsaturated oligogalacturonate transeliminase activity				RHEA:20269|EC:4.2.2.6|MetaCyc:OLIGOGALACTURONIDE-LYASE-RXN									molecular_function											owl:Class	
GO:0008479	biolink:NamedThing	queuine tRNA-ribosyltransferase activity	Catalysis of the reaction: tRNA guanine + queuine = tRNA queuine + guanine.	tmpzr1t_l9r_go_relaxed.owl	queuine transfer ribonucleate ribosyltransferase activity|tRNA transglycosylase activity|guanine, queuine-tRNA transglycosylase activity|[tRNA]-guanine:queuine tRNA-D-ribosyltransferase activity|tRNA-guanine transglycosylase activity|guanine insertion enzyme activity|tRNA guanine transglycosidase activity|transfer ribonucleate glycosyltransferase activity|Q-insertase activity				MetaCyc:QUEUOSINE-TRNA-RIBOSYLTRANSFERASE-RXN|Reactome:R-HSA-6782443|EC:2.4.2.29|RHEA:16633									molecular_function											owl:Class	
GO:1990825	biolink:NamedThing	sequence-specific mRNA binding	Binding to messenger RNA (mRNA) of a specific nucleotide composition or a specific sequence motif.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-08-19T17:42:50Z					molecular_function											owl:Class	
GO:0070420	biolink:NamedThing	Ku-DNA ligase complex	A nonhomologous end joining complex that contains one or more Ku monomers and one or more DNA ligase molecules from the LigC or LigD family, and mediates nonhomologous end joining in bacteria.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0030930	biolink:NamedThing	homotetrameric ADPG pyrophosphorylase complex	A protein complex composed of four identical subunits that possesses ADPG pyrophosphorylase activity. Examples of this component are found in Bacterial species.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0052876	biolink:NamedThing	methylamine dehydrogenase (amicyanin) activity	Catalysis of the reaction: 2O + methylamine + 2 oxidized [amicyanin] = formaldehyde + 2 H+ + NH4+ + 2 reduced [amicyanin].	tmpzr1t_l9r_go_relaxed.owl	primary-amine dehydrogenase|amine dehydrogenase|methylamine dehydrogenase activity|methylamine:amicyanin oxidoreductase (deaminating) activity|MADH activity	https://github.com/geneontology/go-ontology/issues/21650			RHEA:30207|KEGG_REACTION:R00606|EC:1.4.9.1|UM-BBD_reactionID:r0075									molecular_function											owl:Class	
GO:0046917	biolink:NamedThing	triphosphoribosyl-dephospho-CoA synthase activity	Catalysis of the reaction: ATP + 3-dephospho-CoA = 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA + adenine.	tmpzr1t_l9r_go_relaxed.owl	2'-(5''-triphosphoribosyl)-3-dephospho-CoA synthase activity|ATP:dephospho-CoA 5-triphosphoribosyl transferase activity|CitG activity|ATP:3-dephospho-CoA 5''-triphosphoribosyltransferase activity				RHEA:15117|MetaCyc:2.7.8.25-RXN|EC:2.4.2.52									molecular_function											owl:Class	
GO:0042741	biolink:NamedThing	endogenous antibiotic catabolic process	The chemical reactions and pathways resulting in the breakdown of an antibiotic that has originated internally within the cell or organism.	tmpzr1t_l9r_go_relaxed.owl	endogenous antibiotic catabolism|endogenous antibiotic degradation|endogenous antibiotic breakdown													biological_process											owl:Class	
GO:0050364	biolink:NamedThing	tryptophan dimethylallyltransferase activity	Catalysis of the reaction: dimethylallyl diphosphate + L-tryptophan = diphosphate + 4-(3-methylbut-2-enyl)-L-tryptophan.	tmpzr1t_l9r_go_relaxed.owl	DMAT synthetase activity|dimethylallyl-diphosphate:L-tryptophan dimethylallyltransferase activity|dimethylallylpyrophosphate:tryptophan dimethylallyl transferase activity|dimethylallylpyrophosphate:L-tryptophan dimethylallyltransferase activity|4-(gamma,gamma-dimethylallyl)tryptophan synthase activity|dimethylallyltryptophan synthetase activity				RHEA:14173|MetaCyc:TRYPTOPHAN-DIMETHYLALLYLTRANSFERASE-RXN|EC:2.5.1.34									molecular_function											owl:Class	
GO:0005897	biolink:NamedThing	interleukin-9 receptor complex	A protein complex that binds interleukin-9; comprises an alpha and a beta subunit. The alpha chain is specific to the interleukin-9 receptor, whereas the beta chain is shared with the receptors for several other interleukins.	tmpzr1t_l9r_go_relaxed.owl	IL-9 receptor complex													cellular_component											owl:Class	
GO:0140474	biolink:NamedThing	mitochondrion-endoplasmic reticulum membrane tether activity	The binding activity of a molecule that brings together a mitochondrion and an ER membrane either via membrane lipid binding or by interacting with a mitochondrial outer membrane protein, to establish or maintain the localization of the mitochondrion.	tmpzr1t_l9r_go_relaxed.owl	mitochondrion-ER membrane tether activity|ER-mitochondrion membrane tether activity|endoplasmic reticulum-mitochondrion membrane tether activity|mitochondrion-ER membrane adaptor activity|ER-mitochondrion membrane adaptor activity|endoplasmic reticulum-mitochondrion membrane adaptor activity|mitochondrion-endoplasmic reticulum membrane adaptor activity	https://github.com/geneontology/go-ontology/issues/19634						pg	2020-06-22T07:01:14Z					molecular_function											owl:Class	
GO:0031687	biolink:NamedThing	A2A adenosine receptor binding	Binding to an A2A adenosine receptor.	tmpzr1t_l9r_go_relaxed.owl	A2A adenosine receptor ligand													molecular_function											owl:Class	
GO:0042248	biolink:NamedThing	maintenance of polarity of follicular epithelium	The maintenance of an established polarized follicular epithelial sheet.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0031616	biolink:NamedThing	spindle pole centrosome	A centrosome from which one pole of a mitotic or meiotic spindle is organized.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0034043	biolink:NamedThing	5-hydroxymethyluracil DNA N-glycosylase activity	Catalysis of the removal of 5-hydroxymethyluracil bases by cleaving the N-C1' glycosidic bond between the oxidized pyrimidine and the deoxyribose sugar.	tmpzr1t_l9r_go_relaxed.owl	5-hmU DNA N-glycosylase activity													molecular_function											owl:Class	
GO:0046871	biolink:NamedThing	N-acetylgalactosamine binding	Binding to N-acetylgalactosamine, 2-acetamido-2-deoxygalactopyranose, the n-acetyl derivative of galactosamine.	tmpzr1t_l9r_go_relaxed.owl	N-acetylgalactosamine lectin													molecular_function											owl:Class	
GO:0070330	biolink:NamedThing	aromatase activity	Catalysis of the reduction of an aliphatic ring to yield an aromatic ring.	tmpzr1t_l9r_go_relaxed.owl	estrogen synthetase activity				EC:1.14.14.1|UM-BBD_enzymeID:e0551|MetaCyc:UNSPECIFIC-MONOOXYGENASE-RXN|RHEA:17149									molecular_function											owl:Class	
GO:0106154	biolink:NamedThing	perithecium formation	The process of producing flask-shaped fruiting bodies, called perithecia. In the ascomycetous fungi such as Neurospora crassa and Sordaria macrospora, these perithecia are formed in the sexual phase and they discharge ascospores through the ostiolum at the tip of the perithecial neck.	tmpzr1t_l9r_go_relaxed.owl								hjd	2018-09-19T19:12:53Z					biological_process											owl:Class	
GO:0044316	biolink:NamedThing	cone cell pedicle	A specialized axon terminus which is produced by retinal cone cells. Pedicles are large, conical, flat end-feet (8-10 micrometers diameter) of the retinal cone axon that lie more or less side by side on the same plane at the outer edge of the outer plexiform layer (OPL).	tmpzr1t_l9r_go_relaxed.owl	cone pedicle							jl	2010-07-14T01:30:02Z					cellular_component											owl:Class	
GO:0007388	biolink:NamedThing	posterior compartment specification	The process involved in the specification of cell identity in the posterior compartments of the segmented embryo.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0034555	biolink:NamedThing	3,3'-dibromobisphenol A reductive dehalogenase activity	Catalysis of the reaction: 3,3'-dibromobisphenol A + 2 H+ + 2 e- = 3-monobromobisphenol A + HBr.	tmpzr1t_l9r_go_relaxed.owl					EC:1.97.1.-|UM-BBD_reactionID:r0844									molecular_function											owl:Class	
GO:0034277	biolink:NamedThing	ent-cassa-12,15-diene synthase activity	Catalysis of the reaction: ent-copalyl diphosphate = ent-cassa-12,15-diene + diphosphate.	tmpzr1t_l9r_go_relaxed.owl	ent-copalyl-diphosphate diphosphate-lyase (ent-cassa-12,15-diene-forming) activity				EC:4.2.3.28|MetaCyc:RXN-4881|KEGG_REACTION:R09119|RHEA:25532									molecular_function											owl:Class	
GO:0035131	biolink:NamedThing	post-embryonic pelvic fin morphogenesis	The process, occurring after embryonic development, by which the anatomical structures of the pelvic fin are generated and organized. The pelvic fins are bilaterally paired fins mounted in a ventral-lateral position on most fish. These fins are used primarily for lateral mobility and propulsion.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0080076	biolink:NamedThing	caffeoyl CoA:S-adenosyl-L-methionine O-methyltransferase activity	Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to the oxygen atom of a caffeoyl CoA molecule.	tmpzr1t_l9r_go_relaxed.owl								dhl	2009-04-14T03:55:49Z					molecular_function											owl:Class	
GO:0047437	biolink:NamedThing	4-oxalocrotonate decarboxylase activity	Catalysis of the reaction: 4-oxalocrotonate = CO2 + 2-oxopent-4-enoate.	tmpzr1t_l9r_go_relaxed.owl	4-oxalocrotonate carboxy-lyase (2-oxopent-4-enoate-forming)|4-oxalocrotonate carboxy-lyase activity				RHEA:24260|EC:4.1.1.77|UM-BBD_reactionID:r1435|MetaCyc:4.1.1.77-RXN									molecular_function											owl:Class	
GO:0002346	biolink:NamedThing	B cell positive selection	Any process in which B cells are selected to survive based on signaling through the B cell antigen receptor.	tmpzr1t_l9r_go_relaxed.owl	B lymphocyte positive selection|B-lymphocyte positive selection|B-cell positive selection													biological_process											owl:Class	
GO:0004155	biolink:NamedThing	6,7-dihydropteridine reductase activity	Catalysis of the reaction: NADP+ + 5,6,7,8-tetrahydropteridine = NADPH + H+ + 6,7-dihydropteridine.	tmpzr1t_l9r_go_relaxed.owl	5,6,7,8-tetrahydropteridine:NAD(P)H+ oxidoreductase activity|NAD(P)H(2):6,7-dihydropteridine oxidoreductase activity|dihydropteridine reductase (NADH) activity|5,6,7,8-tetrahydropteridine:NAD(P)+ oxidoreductase activity|6,7-dihydropteridine:NAD(P)H oxidoreductase activity|NADPH-dihydropteridine reductase activity|dihydropteridine (reduced nicotinamide adenine dinucleotide) reductase activity|NADPH-specific dihydropteridine reductase activity|DHPR activity|NADH-dihydropteridine reductase activity|dihydropteridine reduction|dihydropteridine reductase activity|NAD(P)H2:6,7-dihydropteridine oxidoreductase activity				EC:1.5.1.34|MetaCyc:1.5.1.34-RXN|Reactome:R-HSA-71130	Note that this function was formerly EC:1.6.99.7.								molecular_function											owl:Class	
GO:0050370	biolink:NamedThing	tyrosine N-monooxygenase activity	Catalysis of the reaction: tyrosine + O2 + NADPH + H+ = N-hydroxytyrosine + NADP+ + H2O.	tmpzr1t_l9r_go_relaxed.owl	L-tyrosine,NADPH:oxygen oxidoreductase (N-hydroxylating)|CYP79A1 activity|tyrosine N-hydroxylase activity				RHEA:22464|MetaCyc:TYROSINE-N-MONOOXYGENASE-RXN									molecular_function											owl:Class	
GO:0042802	biolink:NamedThing	identical protein binding	Binding to an identical protein or proteins.	tmpzr1t_l9r_go_relaxed.owl	isoform-specific homophilic binding|protein homopolymerization													molecular_function											owl:Class	
GO:0047810	biolink:NamedThing	D-alanine:2-oxoglutarate aminotransferase activity	Catalysis of the reaction: D-alanine + 2-oxoglutarate = pyruvate + D-glutamate.	tmpzr1t_l9r_go_relaxed.owl	D-alanine aminotransferase activity|D-alanine transaminase activity|D-aspartate transaminase activity|D-aspartate aminotransferase activity|D-alanine-D-glutamate transaminase activity|D-amino acid transaminase activity|D-aspartic aminotransferase activity|D-amino acid aminotransferase activity|D-amino-acid transaminase activity				EC:2.6.1.21|RHEA:15869|MetaCyc:D-ALANINE-AMINOTRANSFERASE-RXN									molecular_function											owl:Class	
GO:0097732	biolink:NamedThing	9+2 non-motile cilium	A non-motile cilium where the axoneme has a ring of nine outer microtubule doublets plus two central microtubules (and is therefore called a 9+2 axoneme).	tmpzr1t_l9r_go_relaxed.owl	non-motile 9+2 cilium|9+2 immotile cilium					This type of cilia may be present in solitary (e.g. in inner hair cells) or in multiple copies (e.g. in olfactory neurons).		pr	2016-09-29T14:07:33Z					cellular_component											owl:Class	
GO:0004653	biolink:NamedThing	polypeptide N-acetylgalactosaminyltransferase activity	Catalysis of the reaction: UDP-N-acetyl-D-galactosamine + polypeptide = UDP + N-acetyl-D-galactosaminyl-polypeptide. This reaction is the modification of serine or threonine residues in polypeptide chains by the transfer of a N-acetylgalactose from UDP-N-acetylgalactose to the hydroxyl group of the amino acid; it is the first step in O-glycan biosynthesis.	tmpzr1t_l9r_go_relaxed.owl	glycoprotein acetylgalactosaminyltransferase activity|UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase activity|UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase activity|UDP-N-acetylgalactosamine:protein N-acetylgalactosaminyl transferase activity|uridine diphosphoacetylgalactosamine-glycoprotein acetylgalactosaminyltransferase activity|UDP-N-acetyl-D-galactosamine:polypeptide N-acetylgalactosaminyl-transferase activity|UDP-N-acetylgalactosamine:polypeptide N-acetylgalactosaminyltransferase activity|UDP-GalNAc:polypeptide N-acetylgalactosaminyl transferase activity|UDP-N-acetylgalactosamine-glycoprotein N-acetylgalactosaminyltransferase activity|UDP-acetylgalactosamine:peptide-N-galactosaminyltransferase activity|polypeptide-N-acetylgalactosamine transferase activity|protein-UDP acetylgalactosaminyltransferase activity|UDP-N-acetylgalactosamine-protein N-acetylgalactosaminyltransferase activity|UDP-acetylgalactosamine-glycoprotein acetylgalactosaminyltransferase activity|UDP-N-acetylgalactosamine:kappa-casein polypeptide N-acetylgalactosaminyltransferase activity				EC:2.4.1.41|Reactome:R-HSA-5096532|MetaCyc:2.4.1.41-RXN|Reactome:R-HSA-9683760|Reactome:R-HSA-9694438|Reactome:R-HSA-5096537|Reactome:R-HSA-913675|Reactome:R-HSA-8851619									molecular_function											owl:Class	
GO:0008532	biolink:NamedThing	N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity	Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + beta-D-galactosyl-1,4-N-acetyl-D-glucosaminyl-R = UDP + N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-N-acetyl-D-glucosaminyl-R.	tmpzr1t_l9r_go_relaxed.owl	UDP-N-acetyl-D-glucosamine:beta-D-galactosyl-1,4-N-acetyl-D-glucosamine beta-1,3-acetyl-D-glucosaminyltransferase activity|GnTE activity|poly-N-acetyllactosamine extension enzyme activity|UDP-GlcNAc:Galbeta-(1,4)-GlcNAcbeta-r-beta-(1,3)-N-acetylglucosaminyltransferase activity|UDP-GlcNAc:GalR, beta-D-3-N-acetylglucosaminyltransferase activity|UDP-GlcNAc:Galbeta-1,4-GlcNAcbeta-beta-1,3-N-acetylglucosaminyltransferase activity|uridine diphosphoacetylglucosamine-acetyllactosaminide beta1->3-acetylglucosaminyltransferase|N-acetyllactosamine beta(1,3)N-acetylglucosaminyltransferase activity|uridine diphosphoacetylglucosamine-acetyllactosaminide beta-1,3-acetylglucosaminyltransferase|galbeta1->4GlcNAc-R beta1->3 N-acetylglucosaminyltransferase activity				MetaCyc:2.4.1.149-RXN|RHEA:14389|EC:2.4.1.149|Reactome:R-HSA-2025724									molecular_function											owl:Class	
GO:0102241	biolink:NamedThing	soyasaponin III rhamnosyltransferase activity	Catalysis of the reaction: UDP-L-rhamnose + soyasaponin III <=> H+ + UDP + soyasaponin I.	tmpzr1t_l9r_go_relaxed.owl					RHEA:31491|EC:2.4.1.273|MetaCyc:RXN-12320									molecular_function											owl:Class	
GO:0039618	biolink:NamedThing	T=pseudo3 icosahedral viral capsid	The protein coat that surrounds the infective nucleic acid in some virus particles where the subunits (capsomeres) are arranged to form an icosahedron with pseudo T=3 symmetry. The T=pseudo3 capsid is composed of 12 pentameric and 20 hexameric capsomeres.	tmpzr1t_l9r_go_relaxed.owl					VZ:809	T=pseudo3 capsids are not T=3 symmetry as described by Caspar and Klug (PMID:14019094) because the basic unit is composed of three different proteins. Since the three subunits are morphologically very similar, the structure is therefore a pseudo T=3.		bf	2012-07-18T02:10:02Z					cellular_component											owl:Class	
GO:0050452	biolink:NamedThing	CoA-glutathione reductase activity	Catalysis of the reaction: CoA + glutathione + NADP+ = CoA-glutathione + NADPH + H+.	tmpzr1t_l9r_go_relaxed.owl	glutathione:NADP+ oxidoreductase (CoA-acylating)|CoA-glutathione reductase (NADPH) activity|NADPH-dependent coenzyme A-SS-glutathione reductase activity|coenzyme A glutathione disulfide reductase activity|coenzyme A disulfide-glutathione reductase activity|NADPH:CoA-glutathione oxidoreductase activity|NADPH2:CoA-glutathione oxidoreductase activity				EC:1.8.1.10|MetaCyc:COA-GLUTATHIONE-REDUCTASE-NADPH-RXN|RHEA:14617									molecular_function											owl:Class	
GO:0046843	biolink:NamedThing	dorsal appendage formation	Establishment of the dorsal filaments, elaborate specializations of the chorion that protrude from the anterior end of the egg and facilitate embryonic respiration.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0035059	biolink:NamedThing	RCAF complex	A protein complex that facilitates the assembly of nucleosomes on to newly synthesized DNA. In Drosophila, the complex comprises ASF1 and histones H3 and H4.	tmpzr1t_l9r_go_relaxed.owl	replication-coupling assembly factor complex													cellular_component											owl:Class	
GO:0002425	biolink:NamedThing	tolerance induction in urogenital tract	Tolerance induction taking place in the urogenital tract.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0019159	biolink:NamedThing	nicotinamide-nucleotide amidase activity	Catalysis of the reaction: beta-nicotinamide D-ribonucleotide + H2O = beta-nicotinate D-ribonucleotide + NH3.	tmpzr1t_l9r_go_relaxed.owl	NMN deamidase activity|nicotinamide mononucleotide deamidase activity|nicotinamide-D-ribonucleotide amidohydrolase activity|NMN amidohydrolase|nicotinamide mononucleotide amidohydrolase activity				EC:3.5.1.42|RHEA:12400|MetaCyc:NMNAMIDOHYDRO-RXN									molecular_function											owl:Class	
GO:0032354	biolink:NamedThing	response to follicle-stimulating hormone	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a follicle-stimulating hormone stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to FSH stimulus|response to follicle-stimulating hormone stimulus|response to follicle stimulating hormone stimulus													biological_process											owl:Class	
GO:0008709	biolink:NamedThing	cholate 7-alpha-dehydrogenase activity	Catalysis of the reaction: cholate + NAD(+) = 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanate + H(+) + NADH.	tmpzr1t_l9r_go_relaxed.owl	7alpha-hydroxy steroid dehydrogenase activity|7alpha-hydroxysteroid:NAD+ 7-oxidoreductase activity|7alpha-HSDH|7alpha-hydroxysteroid dehydrogenase activity|7-alpha-hydroxysteroid dehydrogenase activity				RHEA:19409|EC:1.1.1.159|KEGG_REACTION:R02792|MetaCyc:7-ALPHA-HYDROXYSTEROID-DEH-RXN									molecular_function											owl:Class	
GO:0090595	biolink:NamedThing	acetyl-CoA:L-lysine N6-acetyltransferase	Catalysis of the reaction: L-lysine + acetyl-CoA = N6-acetyl-L-lysine + CoA + H(+).	tmpzr1t_l9r_go_relaxed.owl								tb	2014-08-21T17:19:06Z					molecular_function											owl:Class	
GO:0009721	biolink:NamedThing	detection of auxin stimulus	The series of events in which an auxin stimulus is received by a cell and converted into a molecular signal.	tmpzr1t_l9r_go_relaxed.owl	perception of auxin stimulus													biological_process											owl:Class	
GO:0003989	biolink:NamedThing	acetyl-CoA carboxylase activity	Catalysis of the reaction: ATP + acetyl-CoA + HCO3- = ADP + phosphate + malonyl-CoA.	tmpzr1t_l9r_go_relaxed.owl	acetyl coenzyme A carboxylase activity|acetyl-CoA:carbon-dioxide ligase (ADP-forming)				Reactome:R-HSA-8876889|RHEA:11308|Reactome:R-HSA-75851|MetaCyc:ACETYL-COA-CARBOXYLTRANSFER-RXN|Reactome:R-HSA-200555|EC:6.4.1.2									molecular_function											owl:Class	
GO:0120122	biolink:NamedThing	prolactin metabolic process	The chemical reactions and pathways involving prolactin, a protein hormone of the anterior pituitary gland that promotes lactation in response to the suckling stimulus of hungry young mammals.	tmpzr1t_l9r_go_relaxed.owl	prolactin metabolism							krc	2018-01-25T17:28:40Z					biological_process											owl:Class	
GO:0050377	biolink:NamedThing	UDP-glucose 4,6-dehydratase activity	Catalysis of the reaction: UDP-D-glucose = H(2)O + UDP-4-dehydro-6-deoxy-D-glucose.	tmpzr1t_l9r_go_relaxed.owl	UDPglucose 4,6-dehydratase activity|UDP-D-glucose-4,6-hydrolyase activity|UDPglucose 4,6-hydro-lyase activity|UDP-glucose 4,6-hydro-lyase activity|UDP-glucose 4,6-hydro-lyase (UDP-4-dehydro-6-deoxy-D-glucose-forming)|UDP-D-glucose oxidoreductase activity				KEGG_REACTION:R00293|RHEA:21500|MetaCyc:UDP-GLUCOSE-46-DEHYDRATASE-RXN|EC:4.2.1.76									molecular_function											owl:Class	
GO:0047051	biolink:NamedThing	D-lactate dehydrogenase (cytochrome c-553) activity	Catalysis of the reaction: (R)-lactate + 2 [Fe(III)cytochrome c553] = 2 [Fe(II)cytochrome c553] + 2 H+ + pyruvate.	tmpzr1t_l9r_go_relaxed.owl	(R)-lactate:ferricytochrome-c-553 2-oxidoreductase activity				MetaCyc:1.1.2.5-RXN|RHEA:16465|EC:1.1.2.5									molecular_function											owl:Class	
GO:0047511	biolink:NamedThing	(S)-methylmalonyl-CoA hydrolase activity	Catalysis of the reaction: (S)-methylmalonyl-CoA + H(2)O = CoA + H(+) + methylmalonate.	tmpzr1t_l9r_go_relaxed.owl	D-methylmalonyl-coenzyme A hydrolase activity				EC:3.1.2.17|MetaCyc:S-METHYLMALONYL-COA-HYDROLASE-RXN|KEGG_REACTION:R02764|RHEA:17345									molecular_function											owl:Class	
GO:1902118	biolink:NamedThing	calcidiol binding	Binding to calcidiol.	tmpzr1t_l9r_go_relaxed.owl	25(OH)D3 binding|25OHD3 binding|calcifediol binding|25-hydroxyvitamin D3 binding|25-hydroxycholecalciferol binding							bf	2013-05-15T14:55:58Z					molecular_function											owl:Class	
GO:0140617	biolink:NamedThing	transvection	An epigenetic regulation of transcription by physical interaction between a cis-acting element (enhancer, silencer) of one allele on one chromosome and the promoter of the corresponding allele on the homologous chromosome. Transvection can lead to either gene activation or repression.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/21038						pg	2021-03-08T18:30:47Z					biological_process											owl:Class	
GO:0071259	biolink:NamedThing	cellular response to magnetism	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a magnetic stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to magnetic stimulus							mah	2009-12-04T03:54:53Z					biological_process											owl:Class	
GO:0008860	biolink:NamedThing	ferredoxin-NAD+ reductase activity	Catalysis of the reaction: reduced ferredoxin + NAD+ = oxidized ferredoxin + NADH + H+.	tmpzr1t_l9r_go_relaxed.owl	NAD-ferredoxin reductase activity|NADH-ferredoxinTOL reductase (component of toluene dioxygenase)|NADH-ferredoxin reductase activity|ferredoxin-linked NAD reductase activity|ferredoxin-NAD reductase activity|reductase, reduced nicotinamide adenine dinucleotide-ferredoxin|NADH-ferredoxin oxidoreductase activity|ferredoxin:NAD+ oxidoreductase activity|NADH2-ferredoxin oxidoreductase activity|NADH-ferredoxinNAP reductase (component of naphthalene dioxygenase multicomponent enzyme system)|NADH flavodoxin oxidoreductase activity|ferredoxin-nicotinamide adenine dinucleotide reductase activity				MetaCyc:FERREDOXIN--NAD+-REDUCTASE-RXN|RHEA:16521|EC:1.18.1.3									molecular_function											owl:Class	
GO:0004158	biolink:NamedThing	dihydroorotate oxidase activity	Catalysis of the reaction: (S)-dihydroorotate + O(2) = H(2)O(2) + orotate.	tmpzr1t_l9r_go_relaxed.owl	4,5-L-dihydroorotate:oxygen oxidoreductase activity|(S)-dihydroorotate:oxygen oxidoreductase activity				RHEA:15441									molecular_function											owl:Class	
GO:0103005	biolink:NamedThing	9,10-epoxystearate hydrolase activity	Catalysis of the reaction: 9,10-epoxystearate + H2O <=> (9R,10S)-dihydroxystearate.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-9806									molecular_function											owl:Class	
GO:1990276	biolink:NamedThing	RNA 5'-methyltransferase activity	Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to the 5'-gamma-phosphate in an RNA molecule.	tmpzr1t_l9r_go_relaxed.owl								pr	2014-01-28T09:44:16Z					molecular_function											owl:Class	
GO:0061417	biolink:NamedThing	negative regulation of transcription from RNA polymerase II promoter in response to oxidative stress	Any process that decreases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is under oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.	tmpzr1t_l9r_go_relaxed.owl								dph	2012-01-23T01:02:10Z					biological_process											owl:Class	
GO:0005873	biolink:NamedThing	plus-end kinesin complex	Any complex that includes a dimer of molecules from the kinesin superfamily and any associated proteins, and moves towards the plus end of a microtubule.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0033782	biolink:NamedThing	24-hydroxycholesterol 7alpha-hydroxylase activity	Catalysis of the reaction: (24S)-hydroxycholesterol + O2 + reduced [NADPH-hemoprotein reductase] = (24S)-7alpha-dihydroxycholesterol + H+ + H2O + oxidized [NADPH-hemoprotein reductase].	tmpzr1t_l9r_go_relaxed.owl	24-cholest-5-ene-3beta,24-diol,NADPH:oxygen oxidoreductase (7alpha-hydroxylating) activity|24-hydroxycholesterol 7alpha-monooxygenase activity	https://github.com/geneontology/go-ontology/issues/21412			EC:1.14.14.26|RHEA:46124|KEGG_REACTION:R07208|MetaCyc:1.14.13.99-RXN	Formerly EC:1.14.13.99.								molecular_function											owl:Class	
GO:0034941	biolink:NamedThing	pyrrole-2-carboxylate decarboxylase activity	Catalysis of the reaction: pryrole-2-carboxylate + H+ = pyrrole + CO2.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0970|EC:4.1.1.93									molecular_function											owl:Class	
GO:0070205	biolink:NamedThing	2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase activity	Catalysis of the reaction: 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1-carboxylate = (1R,6R)-2-succinyl-6-hydroxycyclohexa-2,4-diene-1-carboxylate + pyruvate.	tmpzr1t_l9r_go_relaxed.owl	2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid synthase activity|YfbB|SHCHC synthase activity|MenH|6-hydroxy-2-succinylcyclohexa-2,4-diene-1-carboxylate synthase activity				KEGG_REACTION:R08166|RHEA:25597|EC:4.2.99.20|MetaCyc:RXN-9310									molecular_function											owl:Class	
GO:0102380	biolink:NamedThing	steviolbioside glucosyltransferase activity (rebaudioside B forming)	Catalysis of the reaction: steviolbioside + UDP-alpha-D-glucose = rebaudioside B + UDP + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-13516									molecular_function											owl:Class	
GO:0008691	biolink:NamedThing	3-hydroxybutyryl-CoA dehydrogenase activity	Catalysis of the reaction: (S)-3-hydroxybutanoyl-CoA + NADP+ = 3-acetoacetyl-CoA + NADPH + H+.	tmpzr1t_l9r_go_relaxed.owl	(S)-3-hydroxybutanoyl-CoA:NADP+ oxidoreductase activity|L(+)-3-hydroxybutyryl-CoA dehydrogenase activity|beta-hydroxybutyryl-CoA dehydrogenase activity|dehydrogenase, L-3-hydroxybutyryl coenzyme A (nicotinamide adenine dinucleotide phosphate)|L-(+)-3-hydroxybutyryl-CoA dehydrogenase activity|beta-hydroxybutyryl coenzyme A dehydrogenase activity|BHBD activity				MetaCyc:3-HYDROXYBUTYRYL-COA-DEHYDROGENASE-RXN|RHEA:16197|EC:1.1.1.157									molecular_function											owl:Class	
GO:0003756	biolink:NamedThing	protein disulfide isomerase activity	Catalysis of the rearrangement of both intrachain and interchain disulfide bonds in proteins.	tmpzr1t_l9r_go_relaxed.owl	disulphide bond biosynthesis|disulphide bond formation|protein thiol-disulfide exchange|protein disulfide-isomerase|protein thiol-disulphide exchange|S-S rearrangase activity|protein disulfide-isomerase reaction|protein disulphide isomerase activity|protein cysteine-thiol oxidation				Reactome:R-HSA-8950113|MetaCyc:5.3.4.1-RXN|Reactome:R-HSA-8950456|EC:5.3.4.1|Reactome:R-HSA-8950183							GO:0006467		molecular_function											owl:Class	
GO:1990225	biolink:NamedThing	rhoptry neck	Narrow, electron-dense part of the rhoptry that extends through the conoid at the apical tip of an apicomplexan parasite. The rhoptry neck serves as a duct through which the contents of the rhoptry are secreted after attachment to the host has been completed and at the commencement of invasion.	tmpzr1t_l9r_go_relaxed.owl								pr	2013-11-03T14:19:26Z					cellular_component											owl:Class	
GO:0035974	biolink:NamedThing	meiotic spindle pole body	The microtubule organizing center that forms as part of the meiotic cell cycle; functionally homologous to the animal cell centrosome.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-08-16T11:37:59Z					cellular_component											owl:Class	
GO:0051729	biolink:NamedThing	germline cell cycle switching, mitotic to meiotic cell cycle	The process in which a germline cell switches cell cycle mode from mitotic to meiotic division.	tmpzr1t_l9r_go_relaxed.owl	germline meiotic entry|germline initiation of meiotic cell cycle|germline entry into meiosis|germline entry into meiotic cell cycle|germline conversion to meiosis|germline conversion to meiotic cell cycle|germline cell cycle switching, mitosis to meiosis|germline initiation of meiosis													biological_process											owl:Class	
GO:0004833	biolink:NamedThing	tryptophan 2,3-dioxygenase activity	Catalysis of the reaction: L-tryptophan + O2 = N-formyl-L-kynurenine.	tmpzr1t_l9r_go_relaxed.owl	tryptamine 2,3-dioxygenase activity|L-tryptophan 2,3-dioxygenase activity|L-tryptophan:oxygen 2,3-oxidoreductase (decyclizing)|TDO|tryptamin 2,3-dioxygenase activity|tryptophan pyrrolase activity|tryptophan oxygenase activity|indoleamine-pyrrole 2,3-dioxygenase activity|L-tryptophan pyrrolase activity|indolamine 2,3-dioxygenase activity|tryptophan peroxidase activity				MetaCyc:TRYPTOPHAN-23-DIOXYGENASE-RXN|Reactome:R-HSA-888614|Reactome:R-HSA-71188|RHEA:24536|Reactome:R-HSA-198563|EC:1.13.11.11							GO:0004426		molecular_function											owl:Class	
GO:0070058	biolink:NamedThing	tRNA gene clustering	The process in which tRNA genes, which are not linearly connected on the chromosome, are transported in three dimensions to, and maintained together in, the nucleolus. This clustered positioning leads to transcriptional silencing of nearby RNA polymerase II promoters (termed tRNA gene mediated (tgm) silencing) in S. cerevisiae.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0047113	biolink:NamedThing	aldehyde dehydrogenase (quinone) activity	Catalysis of the reaction: an aldehyde + a quinone + H2O = a carboxylate + a quinol.	tmpzr1t_l9r_go_relaxed.owl	aldehyde:(pyrroloquinoline-quinone) oxidoreductase activity|aldehyde dehydrogenase (pyrroloquinoline-quinone)|aldehyde dehydrogenase (acceptor) activity				RHEA:13881|EC:1.2.5.2|MetaCyc:1.2.99.3-RXN									molecular_function											owl:Class	
GO:0050025	biolink:NamedThing	L-glutamate oxidase activity	Catalysis of the reaction: L-glutamate + O2 + H2O = 2-oxoglutarate + NH3 + H2O2.	tmpzr1t_l9r_go_relaxed.owl	L-glutamic acid oxidase activity|glutamic dehydrogenase (acceptor)|glutamate (acceptor) dehydrogenase activity|glutamate oxidase activity|L-glutamate:oxygen oxidoreductase (deaminating)|glutamic acid oxidase activity				MetaCyc:L-GLUTAMATE-OXIDASE-RXN|RHEA:20728|EC:1.4.3.11									molecular_function											owl:Class	
GO:0050129	biolink:NamedThing	N-formylglutamate deformylase activity	Catalysis of the reaction: N-formyl-L-glutamate + H(2)O = L-glutamate + formate.	tmpzr1t_l9r_go_relaxed.owl	beta-citrylglutamate amidase activity|formylglutamate deformylase activity|beta-citryl-L-glutamate hydrolase activity|beta-citryl-L-glutamate amidase activity|N-formyl-L-glutamate amidohydrolase activity|beta-citryl-L-glutamate-hydrolyzing enzyme|N-formylglutamate hydrolase activity|beta-citryl-L-glutamate amidohydrolase activity				EC:3.5.1.68|KEGG_REACTION:R00525|MetaCyc:N-FORMYLGLUTAMATE-DEFORMYLASE-RXN|RHEA:12476									molecular_function											owl:Class	
GO:0018701	biolink:NamedThing	2,5-dichlorohydroquinone reductive dehalogenase activity	Catalysis of the reaction: organohalide + 2 H+ + 2 e- = R-H + HCl. Reactants include chlorohydroquinone (forms hydroquinone) and 2,5-dichlorohydroquinone (forms chlorohydroquinone).	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_enzymeID:e0366|EC:1.97.1.-									molecular_function											owl:Class	
GO:0045433	biolink:NamedThing	male courtship behavior, veined wing generated song production	The process during wing vibration where the male insect produces a species-specific acoustic signal called a love song.	tmpzr1t_l9r_go_relaxed.owl	male courtship behavior, song production|male courtship behaviour, song production|male courtship behaviour, veined wing generated song production													biological_process											owl:Class	
GO:0033883	biolink:NamedThing	pyridoxal phosphatase activity	Catalysis of the reaction: pyridoxal 5'-phosphate + H2O = pyridoxal + phosphate.	tmpzr1t_l9r_go_relaxed.owl	vitamin B6-phosphate phosphatase activity|vitamin B6 (pyridoxine) phosphatase activity|PLP phosphatase activity|PNP phosphatase activity|pyridoxal-5'-phosphate phosphohydrolase activity				RHEA:20533|EC:3.1.3.74|MetaCyc:3.1.3.74-RXN									molecular_function											owl:Class	
GO:0046019	biolink:NamedThing	regulation of transcription from RNA polymerase II promoter by pheromones	Any process involving pheromones that modulates the frequency, rate or extent or transcription from an RNA polymerase II promoter.	tmpzr1t_l9r_go_relaxed.owl	regulation of transcription from Pol II promoter by pheromones													biological_process											owl:Class	
GO:0018863	biolink:NamedThing	phenanthrene-9,10-epoxide hydrolase (9S,10S-forming) activity	Catalysis of the reaction: phenanthrene-9,10-oxide + H2O = trans-9(S),10(S)-dihydrodiolphenanthrene.	tmpzr1t_l9r_go_relaxed.owl					EC:3.3.2.-|UM-BBD_reactionID:r0496									molecular_function											owl:Class	
GO:1990024	biolink:NamedThing	C bouton	Synaptic bouton found in spinal cord on the soma and proximal dendrites of motor neurons.	tmpzr1t_l9r_go_relaxed.owl					NIF_Subcellular:nlx_subcell_100208			pr	2013-02-06T10:27:41Z					cellular_component											owl:Class	
GO:0034895	biolink:NamedThing	pyridine-3,4-diol dioxygenase activity	Catalysis of the reaction: pryidine-3,4-diol + O2 = 3-(N-formyl)-formiminopyruvate.	tmpzr1t_l9r_go_relaxed.owl					EC:1.13.11.-|UM-BBD_reactionID:r1398									molecular_function											owl:Class	
GO:0035399	biolink:NamedThing	helper T cell enhancement of B cell mediated immune response	Positive regulation of a B cell mediated immune response mediated via cytokine production by a helper T cell.	tmpzr1t_l9r_go_relaxed.owl	helper T cell enhancement of B cell mediated immunity|provision of T cell help to B cell							bf	2010-03-23T10:41:46Z					biological_process											owl:Class	
GO:0004613	biolink:NamedThing	phosphoenolpyruvate carboxykinase (GTP) activity	Catalysis of the reaction: GTP + oxaloacetate = GDP + phosphoenolpyruvate + CO2.	tmpzr1t_l9r_go_relaxed.owl	phosphoenolpyruvic carboxykinase|phosphopyruvate carboxylase (GTP)|phosphoenolpyruvic carboxykinase (GTP)|phosphoenolpyruvate carboxylase (GTP)|GTP:oxaloacetate carboxy-lyase (transphosphorylating)|GTP:oxaloacetate carboxy-lyase (adding GTP; phosphoenolpyruvate-forming)|phosphoenolpyruvic carboxylase (GTP)|phosphopyruvate (guanosine triphosphate) carboxykinase activity				MetaCyc:4.1.1.32-RXN|RHEA:10388|Reactome:R-HSA-70241|Reactome:R-HSA-372819|EC:4.1.1.32									molecular_function											owl:Class	
GO:0047996	biolink:NamedThing	hydroxyphytanate oxidase activity	Catalysis of the reaction: (2S)-2-hydroxyphytanate + O(2) = 2-oxophytanate + H(2)O(2).	tmpzr1t_l9r_go_relaxed.owl	L-2-hydroxyphytanate:oxygen 2-oxidoreductase				KEGG_REACTION:R07151|MetaCyc:HYDROXYPHYTANATE-OXIDASE-RXN|RHEA:21680|EC:1.1.3.27									molecular_function											owl:Class	
GO:0033620	biolink:NamedThing	Mei2 nuclear dot complex	A ribonucleoprotein complex that forms during meiotic prophase in a fixed position in the horsetail nucleus; contains Mei2 and meiRNA. May play a role in the progression of meiosis I.	tmpzr1t_l9r_go_relaxed.owl	Mei2 nuclear dot|Mei2 dot|nuclear body													cellular_component											owl:Class	
GO:0102402	biolink:NamedThing	2-phenylethyl 6-O-beta-D-xylopyranosyl-beta-D-glucopyranoside glucosidase (Yabukita) activity	Catalysis of the reaction: 2-phenylethyl 6-O-beta-D-xylopyranosyl-beta-D-glucopyranoside + H2O = 2-phenylethanol + 6-O-(beta-D-xylopyranosyl)-beta-D-glucopyranose.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-13694|EC:3.2.1.149									molecular_function											owl:Class	
GO:0061611	biolink:NamedThing	mannose to fructose-6-phosphate metabolic process	The chemical reactions and pathways in which mannose, the aldohexose manno-hexose, is converted to fructose-6-phosphate.	tmpzr1t_l9r_go_relaxed.owl	mannose metabolism to fructose-6-phosphate							dph	2014-04-03T13:38:50Z					biological_process											owl:Class	
GO:0017186	biolink:NamedThing	peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase	The chemical reactions and pathways resulting in the formation of peptidyl-pyroglutamic acid, catalyzed by glutaminyl-peptide cyclotransferase.	tmpzr1t_l9r_go_relaxed.owl	2-pyrrolidone-5-carboxylic acid biosynthetic process|peptidyl-pyroglutamic acid anabolism, using glutaminyl-peptide cyclotransferase|peptidyl-pyroglutamic acid formation, using glutaminyl-peptide cyclotransferase|peptidyl-pyroglutamic acid synthesis, using glutaminyl-peptide cyclotransferase|2-pyrrolidone-5-carboxylic acid biosynthesis				RESID:AA0031	See also the molecular function term 'glutaminyl-peptide cyclotransferase activity ; GO:0016603'.								biological_process											owl:Class	
GO:0002197	biolink:NamedThing	xanthine dehydrogenase complex	A homodimeric protein complex having xanthine dehydrogenase activity.	tmpzr1t_l9r_go_relaxed.owl								hjd	2011-10-03T03:55:57Z					cellular_component											owl:Class	
GO:0015043	biolink:NamedThing	leghemoglobin reductase activity	Catalysis of the reaction: NADPH + H+ + 2 ferrileghemoglobin = NADP+ + 2 ferroleghemoglobin.	tmpzr1t_l9r_go_relaxed.owl	ferric leghemoglobin reductase activity|NAD(P)H:ferrileghemoglobin oxidoreductase activity				EC:1.6.2.6|MetaCyc:LEGHEMOGLOBIN-REDUCTASE-RXN									molecular_function											owl:Class	
GO:0004920	biolink:NamedThing	interleukin-10 receptor activity	Combining with interleukin-10 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	IL-10 receptor activity|IL-10R													molecular_function											owl:Class	
GO:1990331	biolink:NamedThing	Hpa2 acetyltransferase complex	A tetrameric protein complex capable of acetyltransferase activity. It can catalyze the transfer of an acetyl group from acetyl-CoA to an acceptor residue on histone H-3, histone H-4, or on polyamines. The complex is also capable of acetylating certain small basic proteins. The two Hpa2 dimers that make up the tetramer are held together by interactions between the bound acetyl-CoA molecules.	tmpzr1t_l9r_go_relaxed.owl								bhm	2014-03-17T10:18:23Z					cellular_component											owl:Class	
GO:0031260	biolink:NamedThing	pseudopodium membrane	The portion of the plasma membrane surrounding a pseudopodium.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0019625	biolink:NamedThing	atrazine catabolic process to cyanuric acid	The chemical reactions and pathways resulting in the breakdown of atrazine, a triazine ring-containing herbicide, into cyanuric acid.	tmpzr1t_l9r_go_relaxed.owl	atrazine breakdown to cyanuric acid|atrazine degradation to cyanuric acid				MetaCyc:P141-PWY									biological_process											owl:Class	
GO:0103060	biolink:NamedThing	kaempferol 3-rhamnoside 7-O-rhamnosyltransferase activity	Catalysis of the reaction: kaempferol-3-rhamnoside + UDP-L-rhamnose <=> kaempferol-3-rhamnoside-7-rhamnoside + UDP.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN1F-475									molecular_function											owl:Class	
GO:1990407	biolink:NamedThing	calcitonin gene-related peptide binding	Binding to calcitonin gene-related peptide (CGRP).	tmpzr1t_l9r_go_relaxed.owl	calcitonin-gene-related peptide binding|CGRP polypeptide binding|calcitonin-gene-related polypeptide binding					An example of this is CALCRL in human (Q16602) in PMID:10882736 (inferred from direct assay/mutant phenotype/etc.).		bhm	2014-07-02T14:22:06Z					molecular_function											owl:Class	
GO:0042361	biolink:NamedThing	menaquinone catabolic process	The chemical reactions and pathways resulting in the breakdown of menaquinones, any of the quinone-derived compounds synthesized by intestinal bacteria. Structurally, menaquinones consist of a methylated naphthoquinone ring structure and side chains composed of a variable number of unsaturated isoprenoid residues. Menaquinones have vitamin K activity and are known as vitamin K2.	tmpzr1t_l9r_go_relaxed.owl	menatetrenone catabolism|vitamin K2 catabolic process|multiprenylmenaquinone catabolic process|menaquinone catabolism|menaquinone breakdown|vitamin K2 catabolism|multiprenylmenaquinone catabolism|menatetrenone catabolic process|menaquinone degradation													biological_process											owl:Class	
GO:0035884	biolink:NamedThing	arabinan biosynthetic process	The chemical reactions and pathways resulting in the formation of arabinan, a polysaccharide composed of arabinose residues.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-06-08T11:01:14Z					biological_process											owl:Class	
GO:0018583	biolink:NamedThing	biphenyl-2,3-diol 1,2-dioxygenase activity	Catalysis of the reaction: biphenyl-2,3-diol + O2 = 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate + H2O.	tmpzr1t_l9r_go_relaxed.owl	biphenyl-2,3-diol dioxygenase activity|2,3-dihydroxybiphenyl dioxygenase activity|biphenyl-2,3-diol:oxygen 1,2-oxidoreductase (decyclizing)|2,3-dihydroxybiphenyl 1,2-dioxygenase activity				MetaCyc:BIPHENYL-23-DIOL-12-DIOXYGENASE-RXN|RHEA:14413|EC:1.13.11.39|UM-BBD_enzymeID:e0127									molecular_function											owl:Class	
GO:0008196	biolink:NamedThing	vitellogenin receptor activity	Receiving vitellogenin, and delivering vitellogenin into the cell via endocytosis.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0047544	biolink:NamedThing	2-hydroxybiphenyl 3-monooxygenase activity	Catalysis of the reaction: biphenyl-2-ol + H(+) + NADH + O(2) = biphenyl-2,3-diol + H(2)O + NAD(+).	tmpzr1t_l9r_go_relaxed.owl	2-hydroxybiphenyl,NADH:oxygen oxidoreductase (3-hydroxylating)				RHEA:11996|EC:1.14.13.44|MetaCyc:2-HYDROXYBIPHENYL-3-MONOOXYGENASE-RXN|UM-BBD_reactionID:r1423|KEGG_REACTION:R03964									molecular_function											owl:Class	
GO:0019923	biolink:NamedThing	alpha-1-microglobulin-chromophore linkage	The covalent linking of the alpha-1-microglobulin chromophore to the protein; the structure of the chromophore is not known. It is probably heterogeneous and involving two cysteines in thioether bonds.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0224									biological_process											owl:Class	
GO:0008421	biolink:NamedThing	long-chain fatty-acyl-glutamate deacylase activity	Catalysis of the reaction: N-long-chain-fatty-acyl-L-glutamate + H2O = a fatty acid anion + L-glutamate.	tmpzr1t_l9r_go_relaxed.owl	long-chain acylglutamate amidase activity|N-long-chain-fatty-acyl-L-glutamate amidohydrolase activity|long-chain aminoacylase activity|long-chain fatty acyl-glutamate deacylase activity|long-chain-fatty-acyl-glutamate deacylase activity				EC:3.5.1.55|RHEA:17517|MetaCyc:3.5.1.55-RXN									molecular_function											owl:Class	
GO:0047792	biolink:NamedThing	cyanohydrin beta-glucosyltransferase activity	Catalysis of the reaction: UDP-glucose + (S)-4-hydroxymandelonitrile = UDP + (S)-4-hydroxy-mandelonitrile beta-D-glucoside.	tmpzr1t_l9r_go_relaxed.owl	cyanohydrin b-glucosyltransferase activity|UDP-D-glucose:(S)-4-hydroxymandelonitrile beta-D-glucosyltransferase activity|UGT85B1 activity|uridine diphosphoglucose-p-hydroxymandelonitrile glucosyltransferase activity|UDP-glucose:p-hydroxymandelonitrile-O-glucosyltransferase activity|UDP-glucose:(S)-4-hydroxymandelonitrile beta-D-glucosyltransferase activity|uridine diphosphoglucose:aldehyde cyanohydrin beta-glucosyltransferase activity|UDP-glucose-p-hydroxymandelonitrile glucosyltransferase activity|uridine diphosphoglucose-cyanohydrin glucosyltransferase activity				RHEA:12853|EC:2.4.1.85									molecular_function											owl:Class	
GO:0035327	biolink:NamedThing	transcriptionally active chromatin	The ordered and organized complex of DNA and protein that forms regions of the chromosome that are being actively transcribed.	tmpzr1t_l9r_go_relaxed.owl								bf	2010-02-26T10:23:02Z					cellular_component											owl:Class	
GO:0106323	biolink:NamedThing	(S)-limonene 1,2-monooxygenase NADPH activity	Catalysis of the reaction: (4S)-limonene + NADPH+= + H+ + O2 = NADP+ + H2O + (4S)-limonene-1,2-epoxide.	tmpzr1t_l9r_go_relaxed.owl					RHEA:26085			hjd	2020-09-23T15:35:43Z					molecular_function											owl:Class	
GO:0102530	biolink:NamedThing	aclacinomycin T methylesterase activity	Catalysis of the reaction: aclacinomycin T(1+) + H2O <=> 15-demethylaclacinomycin T  + methanol + H+.	tmpzr1t_l9r_go_relaxed.owl					EC:3.1.1.95|MetaCyc:RXN-14703|RHEA:37891									molecular_function											owl:Class	
GO:0070027	biolink:NamedThing	carbon monoxide sensor activity	Binding to and responding, e.g. by conformational change, to changes in the cellular level of carbon monoxide (CO).	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0019667	biolink:NamedThing	anaerobic L-alanine catabolic process	The anaerobic chemical reactions and pathways resulting in the breakdown of L-alanine, yielding energy in the form of ATP.	tmpzr1t_l9r_go_relaxed.owl	L-alanine fermentation													biological_process											owl:Class	
GO:0031787	biolink:NamedThing	H9 melatonin receptor binding	Binding to a H9 melatonin receptor.	tmpzr1t_l9r_go_relaxed.owl	H9 melatonin receptor ligand													molecular_function											owl:Class	
GO:0047302	biolink:NamedThing	UDP-2-acetamido-4-amino-2,4,6-trideoxyglucose transaminase activity	Catalysis of the reaction: 2-oxoglutarate + UDP-2-acetamido-4-amino-2,4,6-trideoxy-D-glucose = L-glutamate + UDP-2-acetamido-4-dehydro-2,6-dideoxy-beta-D-glucose.	tmpzr1t_l9r_go_relaxed.owl	UDP-4-amino-2-acetamido-2,4,6-trideoxyglucose transaminase activity|uridine diphospho-4-amino-2-acetamido-2,4,6-trideoxyglucose aminotransferase activity|UDP-2-acetamido-4-amino-2,4,6-trideoxyglucose:2-oxoglutarate aminotransferase activity|UDP-4-amino-2-acetamido-2,4,6-trideoxyglucose aminotransferase activity				KEGG_REACTION:R04529|EC:2.6.1.34|RHEA:31663|MetaCyc:2.6.1.34-RXN									molecular_function											owl:Class	
GO:0017090	biolink:NamedThing	meprin A complex	A protein complex that is located in the cell membrane, and is involved in the metabolism of peptides, including neuropeptides. The complex has metalloendopeptidase activity that catalyzes the hydrolysis of protein and peptide substrates, preferentially on carboxyl side of hydrophobic residues.	tmpzr1t_l9r_go_relaxed.owl	PABA peptide hydrolase complex													cellular_component											owl:Class	
GO:0140594	biolink:NamedThing	xyloglucan-specific endo-beta-1,4-glucanase inhibitor activity	Stops, prevents or reduces the activity of xyloglucan-specific endo-beta-1,4-glucanase.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/20814						pg	2021-02-09T18:59:49Z					molecular_function											owl:Class	
GO:0017188	biolink:NamedThing	aspartate N-acetyltransferase activity	Catalysis of the reaction: L-aspartate + acetyl-CoA = N-acetyl-L-aspartate + CoA + H(+).	tmpzr1t_l9r_go_relaxed.owl	L-aspartate N-acetyltransferase activity|acetyl-CoA:L-aspartate N-acetyltransferase activity|aspartate acetyltransferase activity				Reactome:R-HSA-8954468|EC:2.3.1.17|KEGG_REACTION:R00487|RHEA:14165|MetaCyc:ASPARTATE-N-ACETYLTRANSFERASE-RXN									molecular_function											owl:Class	
GO:0019416	biolink:NamedThing	polythionate oxidation	The chemical reactions and pathways resulting in the conversion of thiosulfate to tetrathionate, using cytochrome c as an electron acceptor.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:THIOSULFOX-PWY									biological_process											owl:Class	
GO:0036032	biolink:NamedThing	neural crest cell delamination	The negative regulation of cell adhesion process in which a neural crest cell physically separates from the rest of the neural tube.	tmpzr1t_l9r_go_relaxed.owl	neural crest cell individualization|neural crest cell segregation|neural crest cell emigration							bf	2011-10-31T03:50:30Z					biological_process											owl:Class	
GO:0033946	biolink:NamedThing	xyloglucan-specific endo-beta-1,4-glucanase activity	Catalysis of the reaction: xyloglucan + H2O = xyloglucan oligosaccharides. This reaction is the endohydrolysis of (1->4)-beta-D-glucosidic linkages in xyloglucan.	tmpzr1t_l9r_go_relaxed.owl	[(1->6)-beta-D-xylo]-(1->4)-beta-D-glucan glucanohydrolase activity|xyloglucanendohydrolase activity|xyloglucan endo-beta-1,4-glucanase activity|XH|1,4-beta-D-glucan glucanohydrolase activity|XEG|xyloglucanase activity				EC:3.2.1.151|MetaCyc:3.2.1.151-RXN									molecular_function											owl:Class	
GO:0036209	biolink:NamedThing	9beta-pimara-7,15-diene oxidase activity	Catalysis of the reaction: 9beta-pimara-7,15-diene + 3 O2 + 3 reduced [NADPH-hemoprotein reductase] = 9beta-pimara-7,15-dien-19-oate + 4 H+ + 4 H2O + 3 oxidized [NADPH-hemoprotein reductase].	tmpzr1t_l9r_go_relaxed.owl	9-beta-stemod-13(17)-ene oxidase activity	https://github.com/geneontology/go-ontology/issues/21412			EC:1.14.14.111|RHEA:31951|KEGG_REACTION:R09865|MetaCyc:RXN-15437	Formerly EC:1.14.13.144.		bf	2012-04-25T11:11:55Z			GO:0102609		molecular_function											owl:Class	
GO:0061655	biolink:NamedThing	Pup conjugating enzyme activity	Isoenergetic transfer of Pup from one protein to another via the reaction X-Pup + Y -> Y-Pup + X, where both the X-Pup and Y-Pup linkages are thioester bonds between the C-terminal amino acid of Pup and a sulfhydryl side group of a cysteine residue.	tmpzr1t_l9r_go_relaxed.owl	E2							dph	2014-11-06T13:30:46Z					molecular_function											owl:Class	
GO:0015673	biolink:NamedThing	silver ion transport	The directed movement of silver (Ag) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	silver transport													biological_process											owl:Class	
GO:0090639	biolink:NamedThing	phosphatidylcholine biosynthesis from choline and CDP-diacylglycerol	The phosphatidylcholine biosynthetic process that involves a one-step direct condensation of choline with CDP-diacylglycerol to form phosphatidylcholine.	tmpzr1t_l9r_go_relaxed.owl								tb	2015-04-23T15:56:12Z					biological_process											owl:Class	
GO:1990539	biolink:NamedThing	fructose import across plasma membrane	The directed movement of fructose substance from outside of a cell, across the plasma membrane and into the cytosol.	tmpzr1t_l9r_go_relaxed.owl								vw	2014-11-19T10:57:17Z					biological_process											owl:Class	
GO:0097672	biolink:NamedThing	SCF-Pof5 ubiquitin ligase complex	An SCF ubiquitin ligase complex in which the F-box protein is Pof5 in S. pombe (YDR306C in S. cerevisiae).	tmpzr1t_l9r_go_relaxed.owl	SCF-YDR306C ubiquitin ligase complex							pr	2014-10-06T10:30:10Z					cellular_component											owl:Class	
GO:1901855	biolink:NamedThing	5,6,7,8-tetrahydrosarcinapterin biosynthetic process	The chemical reactions and pathways resulting in the formation of 5,6,7,8-tetrahydrosarcinapterin.	tmpzr1t_l9r_go_relaxed.owl	5,6,7,8-tetrahydrosarcinapterin synthesis|5,6,7,8-tetrahydrosarcinapterin anabolism|5,6,7,8-tetrahydrosarcinapterin biosynthesis|5,6,7,8-tetrahydrosarcinapterin formation							yaf	2013-01-28T11:48:05Z					biological_process											owl:Class	
GO:0051741	biolink:NamedThing	2-methyl-6-phytyl-1,4-benzoquinone methyltransferase activity	Catalysis of the reaction: 2-methyl-6-phytyl-1,4-benzoquinone + S-adenosyl-methionine = 2,3-dimethyl-6-phytyl-1,4-benzoquinone + S-adenosyl-homocysteine.	tmpzr1t_l9r_go_relaxed.owl	MPBQ methyltransferase activity				RHEA:37979|MetaCyc:RXN-2542									molecular_function											owl:Class	
GO:0102743	biolink:NamedThing	eriodictyol,NADPH:oxygen oxidoreductase activity	Catalysis of the reaction: H+ + eriodictyol + NADPH + O2 <=> 2-(3,4-dihydroxyphenyl)-5-hydroxy-4-oxo-4H-chromen-7-olate luteolin-7-olate(1-) + NADP + 2 H2O.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-7653									molecular_function											owl:Class	
GO:1905502	biolink:NamedThing	acetyl-CoA binding	Binding to acetyl-CoA, an acyl-CoA having acetyl as its S-acetyl component.	tmpzr1t_l9r_go_relaxed.owl	acetyl-coenzyme A binding							bc	2016-09-27T16:33:44Z					molecular_function											owl:Class	
GO:1902712	biolink:NamedThing	G protein-coupled GABA receptor complex	A protein complex which is capable of G protein-coupled GABA receptor activity. In human, it is usually a heterodimer composed of GABA-B receptor subunits 1 and 2.	tmpzr1t_l9r_go_relaxed.owl	G-protein coupled GABA receptor complex					An example of this is GABR1 in human (UniProt symbol Q9UBS5) in PMID:18790874.		bhm	2014-02-21T09:47:03Z					cellular_component											owl:Class	
GO:0035147	biolink:NamedThing	branch fusion, open tracheal system	Fusing of specific tracheal branches in an open tracheal system to branches from neighboring hemisegments to form a continuous tracheal network. Branch fusion is mediated by individual cells at the tip of each branch, which contact a similar cell and undergo a coordinated series of morphogenetic events that create a bicellular fusion joint.	tmpzr1t_l9r_go_relaxed.owl	tracheal branch fusion													biological_process											owl:Class	
GO:0102317	biolink:NamedThing	4-methylaminobutyrate oxidase (demethylating) activity	Catalysis of the reaction: 4-(methylamino)butyric acid  + O2 + H2O <=> gamma-aminobutyric acid  + formaldehyde + hydrogen peroxide.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-13067|EC:1.5.3.19|RHEA:33907									molecular_function											owl:Class	
GO:0043464	biolink:NamedThing	malolactic fermentation	The anaerobic enzymatic conversion of L-malate to L-lactate and carbon dioxide, yielding energy in the form of ATP.	tmpzr1t_l9r_go_relaxed.owl	malate fermentation|L-malate fermentation|malolactate fermentation|malo-lactate fermentation				Wikipedia:Malolactic_fermentation									biological_process											owl:Class	
GO:0103066	biolink:NamedThing	4alpha-carboxy-4beta-methyl-5alpha-cholesta-8-en-3beta-ol:NAD(P)+ 3-oxidoreductase (decarboxylating) activity	Catalysis of the reaction: 4alpha-carboxy-4beta-methyl-5alpha-cholesta-8-en-3beta-ol + NAD(P) = 4alpha-methyl-5alpha-cholesta-8-en-3-one + carbon dioxide + NAD(P)H.	tmpzr1t_l9r_go_relaxed.owl					EC:1.1.1.170|MetaCyc:RXN66-18									molecular_function											owl:Class	
GO:0000839	biolink:NamedThing	Hrd1p ubiquitin ligase ERAD-L complex	A multiprotein complex that recognizes and ubiquitinates proteins with misfolded luminal domains during ER-associated protein degradation (ERAD). In S. cerevisiae, this complex contains the ubiquitin ligase Hrd1p.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0018530	biolink:NamedThing	(R)-6-hydroxynicotine oxidase activity	Catalysis of the reaction: (R)-6-hydroxynicotine + H(2)O + O(2) = 6-hydroxypseudooxynicotine + H(2)O(2).	tmpzr1t_l9r_go_relaxed.owl	D-6-hydroxynicotine oxidase activity|6-hydroxy-D-nicotine oxidase activity|(R)-6-hydroxynicotine:oxygen oxidoreductase activity				EC:1.5.3.6|MetaCyc:R-6-HYDROXYNICOTINE-OXIDASE-RXN|RHEA:10012|UM-BBD_reactionID:r0477|KEGG_REACTION:R07170									molecular_function											owl:Class	
GO:1902927	biolink:NamedThing	inulin catabolic process	The chemical reactions and pathways resulting in the breakdown of inulin.	tmpzr1t_l9r_go_relaxed.owl	inulin degradation|inulin catabolism|inulin breakdown					SUC2 in S. cerevisiae strain JZ1C in PMID:23104410.		se	2014-04-21T23:54:45Z					biological_process											owl:Class	
GO:0043251	biolink:NamedThing	sodium-dependent organic anion transport	The directed, sodium-dependent, movement of organic anions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0045430	biolink:NamedThing	chalcone isomerase activity	Catalysis of the reaction: a chalcone = a flavanone.	tmpzr1t_l9r_go_relaxed.owl	chalcone--flavonone isomerase activity|chalcone-flavanone isomerase activity|flavanone lyase (decyclizing)				EC:5.5.1.6|MetaCyc:CHALCONE-ISOMERASE-RXN									molecular_function											owl:Class	
GO:0002051	biolink:NamedThing	osteoblast fate commitment	The commitment of mesenchymal cells to the specific cell fate of an osteoblast. An osteoblast is a bone-forming cell which secretes an extracellular matrix. Hydroxyapatite crystals are then deposited into the matrix to form bone.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0030909	biolink:NamedThing	non-intein-mediated protein splicing	The post-translational removal of peptide sequences from within a protein sequence, by a process not involving inteins.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0005499	biolink:NamedThing	vitamin D binding	Binding to vitamin D, any of a group of related, fat-soluble compounds that are derived from delta-5,7 steroids and play a central role in calcium metabolism. Specific forms of vitamin D include calciferol (ergocalciferol; vitamin D2) and cholecalciferol (calciol; vitamin D3).	tmpzr1t_l9r_go_relaxed.owl	calciferol binding|cholecalciferol binding|ergocalciferol binding													molecular_function											owl:Class	
GO:0050314	biolink:NamedThing	sym-norspermidine synthase activity	Catalysis of the reaction: 1,3-diaminopropane + S-adenosylmethioninamine = S-methyl-5'-thioadenosine + bis(3-aminopropyl)amine + H(+).	tmpzr1t_l9r_go_relaxed.owl	S-adenosylmethioninamine:propane-1,3-diamine 3-aminopropyltransferase activity				KEGG_REACTION:R03271|MetaCyc:SYM-NORSPERMIDINE-SYNTHASE-RXN|EC:2.5.1.23|RHEA:23244									molecular_function											owl:Class	
GO:0015955	biolink:NamedThing	pyrimidine deoxyribonucleotide interconversion	The chemical reactions and pathways by which a pyrimidine deoxyribonucleotide is synthesized from another pyrimidine deoxyribonucleotide.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0061477	biolink:NamedThing	response to aromatase inhibitor	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an aromatase inhibitor stimulus.	tmpzr1t_l9r_go_relaxed.owl								dph	2012-11-07T09:08:36Z					biological_process											owl:Class	
GO:0001631	biolink:NamedThing	cysteinyl leukotriene receptor activity	Combining with a cysteinyl leukotriene to initiate a change in cell activity. Cysteinyl leukotrienes are leukotrienes that contain a peptide group based on cysteine.	tmpzr1t_l9r_go_relaxed.owl	CysLT receptor													molecular_function											owl:Class	
GO:0018622	biolink:NamedThing	4-chlorophenylacetate 3,4-dioxygenase activity	Catalysis of the reaction: 4-chlorophenylacetate + NADH + O(2) = 3,4-dihydroxyphenylacetate + chloride + NAD(+).	tmpzr1t_l9r_go_relaxed.owl	4-chlorophenylacetate,NADH:oxygen oxidoreductase (3,4-hydroxylating, dechlorinating)				KEGG_REACTION:R03306|MetaCyc:1.14.12.9-RXN|EC:1.14.12.9|RHEA:14689|UM-BBD_reactionID:r0308									molecular_function											owl:Class	
GO:0072391	biolink:NamedThing	phenol biosynthetic process	The chemical reactions and pathways resulting in the formation of phenol, a compound that consists of a benzene ring with one attached hydroxyl group.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-12-06T04:08:04Z					biological_process											owl:Class	
GO:0033407	biolink:NamedThing	UCA codon-amino acid adaptor activity	A triplet codon-amino acid adaptor activity that recognizes a UCA codon.	tmpzr1t_l9r_go_relaxed.owl	TCA codon-amino acid adaptor activity|serine tRNA					Note that in the standard genetic code, TCA codes for serine.								molecular_function											owl:Class	
GO:0003825	biolink:NamedThing	alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity	Catalysis of the reaction: UDP-glucose + D-glucose-6-phosphate = UDP + alpha,alpha-trehalose-6-phosphate.	tmpzr1t_l9r_go_relaxed.owl	UDPglucose:D-glucose-6-phosphate 1-alpha-D-glucosyltransferase activity|phosphotrehalose-uridine diphosphate transglucosylase activity|UDP-glucose-glucosephosphate glucosyltransferase activity|UDPglucose-glucose-phosphate glucosyltransferase activity|trehalose-phosphate synthetase activity|UDP-glucose-glucose-phosphate glucosyltransferase activity|trehalosephosphate-UDP glucosyltransferase activity|uridine diphosphoglucose phosphate glucosyltransferase activity|trehalose-phosphate synthase activity|trehalose phosphate-uridine diphosphate glucosyltransferase activity|trehalose 6-phosphate synthase activity|trehalose phosphate synthase activity|transglucosylase activity|alpha,alpha-trehalose phosphate synthase (UDP-forming)|trehalosephosphate-UDP glucosyl transferase activity|trehalose phosphate synthetase activity|trehalose-P synthetase activity|trehalose 6-phosphate synthetase activity|UDP-glucose:D-glucose-6-phosphate 1-alpha-D-glucosyltransferase activity				MetaCyc:TREHALOSE6PSYN-RXN|EC:2.4.1.15|RHEA:18889									molecular_function											owl:Class	
GO:0051745	biolink:NamedThing	4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase activity	Catalysis of the reaction: (E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate + NAD(P)H + H+ = isopentenyl diphosphate + NAD(P)+ + H2O. Note that (E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate is an alternative name for 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.	tmpzr1t_l9r_go_relaxed.owl	isopentenyl-diphosphate:NAD(P)+ oxidoreductase activity|4-hydroxy-3-methylbut-2-enyl diphosphate reductase activity				EC:1.17.7.4|MetaCyc:ISPH2-RXN									molecular_function											owl:Class	
GO:0019750	biolink:NamedThing	chloroplast localization	Any process in which a chloroplast is transported to, and/or maintained in, a specific location within the cell. A chloroplast is a chlorophyll-containing plastid found in cells of algae and higher plants.	tmpzr1t_l9r_go_relaxed.owl	chloroplast localisation													biological_process											owl:Class	
GO:0018658	biolink:NamedThing	salicylate 1-monooxygenase activity	Catalysis of the reaction: salicylate + NADH + H+ + O2 = catechol + NAD+ + H2O + CO2.	tmpzr1t_l9r_go_relaxed.owl	salicylate 1-hydroxylase activity|salicylate monooxygenase activity|salicylate,NADH:oxygen oxidoreductase (1-hydroxylating, decarboxylating)|salicylate hydroxylase activity|salicylic hydroxylase activity|salicylate hydroxylase (decarboxylating)				RHEA:11004|UM-BBD_enzymeID:e0149|MetaCyc:SALICYLATE-1-MONOOXYGENASE-RXN|EC:1.14.13.1									molecular_function											owl:Class	
GO:0072435	biolink:NamedThing	response to mitotic G2 DNA damage checkpoint signaling	A process that occurs in response to signals generated as a result of mitotic G2/M transition DNA damage checkpoint signaling.	tmpzr1t_l9r_go_relaxed.owl	response to mitotic G2/M transition decatenation checkpoint signaling|response to mitotic G2/M transition DNA damage checkpoint signaling|mitotic G2/M transition decatenation checkpoint effector process|response to signal involved in mitotic G2/M transition DNA damage checkpoint|mitotic G2/M transition DNA damage checkpoint effector process|response to signal involved in mitotic G2/M transition decatenation checkpoint							mah	2010-12-08T04:44:01Z			GO:0072458		biological_process											owl:Class	
GO:0015344	biolink:NamedThing	siderophore uptake transmembrane transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: siderophore-iron(ferrioxamine)(out) + H+(out) = siderophore-iron(ferrioxamine)(in) + H+(in).	tmpzr1t_l9r_go_relaxed.owl	siderophore-iron uptake transmembrane transporter activity|siderochrome-iron (ferrioxamine) uptake transporter|ferrioxamine uptake transmembrane transporter activity													molecular_function											owl:Class	
GO:0004080	biolink:NamedThing	biotin-[propionyl-CoA-carboxylase (ATP-hydrolyzing)] ligase activity	Catalysis of the reaction: ATP + biotin + apo-(propanoyl-CoA:carbon-dioxide ligase (ADP-forming)) = AMP + diphosphate + (propanoyl-CoA:carbon-dioxide ligase (ADP-forming)).	tmpzr1t_l9r_go_relaxed.owl	propionyl-CoA holocarboxylase synthetase activity|holocarboxylase synthetase activity|biotin-propionyl coenzyme A carboxylase synthetase activity|biotin-propionyl-CoA-carboxylase (ATP-hydrolysing) ligase activity|biotin-[propionyl-CoA-carboxylase (ATP-hydrolyzing)] synthetase activity|biotin:apo-propanoyl-CoA:carbon-dioxide ligase (ADP-forming) ligase (AMP-forming)|propionyl coenzyme A holocarboxylase synthetase activity|biotin-propionyl-CoA-carboxylase (ATP-hydrolysing) synthetase activity				EC:6.3.4.10|RHEA:11204|MetaCyc:6.3.4.10-RXN									molecular_function											owl:Class	
GO:0052574	biolink:NamedThing	UDP-galactose biosynthetic process	The chemical reactions and pathways resulting in the formation of UDP-D-galactose, a substance composed of D-galactose in glycosidic linkage with guanosine diphosphate.	tmpzr1t_l9r_go_relaxed.owl	UDP-galactose biosynthesis|uridine diphosphate galactose biosynthesis|UDP-D-galactose biosynthesis|UDP-D-galactopyranose biosynthesis|uridine diphosphate galactose biosynthetic process|UDP-D-galactopyranose biosynthetic process|UDP-D-galactose biosynthetic process								2010-07-23T03:52:40Z					biological_process											owl:Class	
GO:0047751	biolink:NamedThing	cholestenone 5-alpha-reductase activity	Catalysis of the reaction: 5alpha-cholestan-3-one + NADP(+) = cholest-4-en-3-one + H(+) + NADPH.	tmpzr1t_l9r_go_relaxed.owl	3-oxosteroid delta4-dehydrogenase|cholestenone 5alpha-reductase activity|testosterone delta4-5alpha-reductase activity|steroid 5alpha-hydrogenase activity|cholest-4-en-3-one 5alpha-reductase activity|testosterone delta4-hydrogenase activity|4-ene-5alpha-reductase activity|3-oxo-5alpha-steroid:NADP+ delta4-oxidoreductase activity|3-oxosteroid 5alpha-reductase activity|cholestenone 5a-reductase activity|reduced nicotinamide adenine dinucleotide phosphate:Delta4-3-ketosteroid 5alpha-oxidoreductase activity|testosterone 5alpha-reductase|delta4-3-ketosteroid 5alpha-oxidoreductase activity|5alpha-reductase|4-ene-3-oxosteroid 5alpha-reductase activity|steroid 5alpha-reductase				EC:1.3.1.22|KEGG_REACTION:R02610|MetaCyc:CHOLESTENONE-5-ALPHA-REDUCTASE-RXN|RHEA:24552									molecular_function											owl:Class	
GO:0031417	biolink:NamedThing	NatC complex	A conserved complex that catalyzes the transfer of an acetyl group to the N-terminal residue of a protein acceptor molecule that has a Met-Ile, Met-Leu, Met-Trp, or Met-Phe N-terminus. In Saccharomyces the complex includes Mak3p, Mak10p, and Mak31p.	tmpzr1t_l9r_go_relaxed.owl	N-terminal acetyltransferase C complex													cellular_component											owl:Class	
GO:0070034	biolink:NamedThing	telomerase RNA binding	Binding to the telomerase RNA template.	tmpzr1t_l9r_go_relaxed.owl	TERC binding													molecular_function											owl:Class	
GO:0102069	biolink:NamedThing	zerumbone synthase activity	Catalysis of the reaction: 8-hydroxy-alpha-humulene + NAD <=> zerumbone + NADH + H+.	tmpzr1t_l9r_go_relaxed.owl					RHEA:32327|EC:1.1.1.326|MetaCyc:RXN-10629									molecular_function											owl:Class	
GO:1990868	biolink:NamedThing	response to chemokine	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemokine stimulus.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-09-25T16:37:00Z					biological_process											owl:Class	
GO:0043640	biolink:NamedThing	benzoate catabolic process via hydroxylation	The chemical reactions and pathways resulting in the breakdown of benzoate, by its hydroxylation to cis-1,2-dihydroxybenzoate followed by dehydrogenation to catechol.	tmpzr1t_l9r_go_relaxed.owl	benzoate breakdown via hydroxylation|benzoate degradation via hydroxylation				MetaCyc:PWY-2503									biological_process											owl:Class	
GO:0034916	biolink:NamedThing	2-methylhexanoyl-CoA dehydrogenase activity	Catalysis of the reaction: 2-methylhexanoyl-CoA = 2-methylhex-2-enoyl-CoA + 2 H+ + e-.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0928|EC:1.3.99.-									molecular_function											owl:Class	
GO:0102111	biolink:NamedThing	gibberellin A20,2-oxoglutarate:oxygen oxidoreductase activity	Catalysis of the reaction: gibberellin A20 + 2-oxoglutarate + O2 <=> gibberellin A29 + succinate + carbon dioxide.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-113									molecular_function											owl:Class	
GO:0046510	biolink:NamedThing	UDP-sulfoquinovose:DAG sulfoquinovosyltransferase activity	Catalysis of the reaction: UDP-sulfoquinovose + 1,2-diacylglycerol = sulfoquinovosyldiacylglycerol + UDP.	tmpzr1t_l9r_go_relaxed.owl	UDP-sulphoquinovose:DAG sulphoquinovosyltransferase activity|sulfolipid synthase				RHEA:49468|MetaCyc:RXN-1224									molecular_function											owl:Class	
GO:0075341	biolink:NamedThing	host cell PML body	A nuclear body that reacts against SP100 auto-antibodies (PML = promyelocytic leukemia) located within a cell of a host organism.	tmpzr1t_l9r_go_relaxed.owl	host cell PML nuclear body|host cell PML NB													cellular_component											owl:Class	
GO:0015054	biolink:NamedThing	gastrin receptor activity	Combining with gastrin and transmitting the signal across the membrane by activating an associated G-protein to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	cholecystokinin-B receptor activity													molecular_function											owl:Class	
GO:0015052	biolink:NamedThing	beta3-adrenergic receptor activity	Combining with epinephrine or norepinephrine to initiate a change in cell activity via activation of a G protein, with pharmacological characteristics of beta3-adrenergic receptors.	tmpzr1t_l9r_go_relaxed.owl	beta3 adrenoceptor													molecular_function											owl:Class	
GO:0017065	biolink:NamedThing	single-strand selective uracil DNA N-glycosylase activity	Catalysis of the cleavage of the N-C1' glycosidic bond between the damaged DNA base and the deoxyribose sugar, releasing a free base and leaving an apyrimidinic (AP) site. Enzymes with this activity recognize and remove uracil bases present in single-stranded DNA.	tmpzr1t_l9r_go_relaxed.owl	single-strand selective monofunctional uracil-DNA glycosylase activity				Reactome:R-HSA-110221									molecular_function											owl:Class	
GO:0004844	biolink:NamedThing	uracil DNA N-glycosylase activity	Catalysis of the cleavage of the N-C1' glycosidic bond between the damaged DNA base and the deoxyribose sugar, releasing a free base and leaving an apyrimidinic (AP) site. Enzymes with this activity recognize and remove uracil bases in DNA that result from the deamination of cytosine or the misincorporation of dUTP opposite an adenine.	tmpzr1t_l9r_go_relaxed.owl	uracil-DNA glycosylase activity				Reactome:R-HSA-110217|Reactome:R-HSA-110215									molecular_function											owl:Class	
GO:0072137	biolink:NamedThing	condensed mesenchymal cell proliferation	The multiplication or reproduction of cells, resulting in the expansion of a condensed mesenchymal cell population. A condensed mesenchymal cell population is a population of adherent mesenchymal cells.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-02-22T02:38:54Z					biological_process											owl:Class	
GO:1903120	biolink:NamedThing	protein localization to actin filament bundle	A process in which a protein is transported to, or maintained in, the location of an actin filament bundle.	tmpzr1t_l9r_go_relaxed.owl	protein localization in actin filament bundle|protein localization to actin cable|protein localisation to actin filament bundle|protein localisation in actin filament bundle							mah	2014-06-16T11:27:16Z					biological_process											owl:Class	
GO:0032148	biolink:NamedThing	activation of protein kinase B activity	Any process that initiates the activity of the inactive enzyme protein kinase B.	tmpzr1t_l9r_go_relaxed.owl	protein kinase B activation													biological_process											owl:Class	
GO:0106283	biolink:NamedThing	ursodeoxycholate 7-beta-dehydrogenase (NAD+) activity	Catalysis of the reaction: NAD(+) + ursodeoxycholate = 7-oxolithocholate + H(+) + NADH.	tmpzr1t_l9r_go_relaxed.owl					RHEA:42028			hjd	2020-07-29T17:52:44Z					molecular_function											owl:Class	
GO:1990275	biolink:NamedThing	preribosome binding	Binding to a preribosome.	tmpzr1t_l9r_go_relaxed.owl								tb	2014-01-16T19:14:50Z					molecular_function											owl:Class	
GO:0070725	biolink:NamedThing	Yb body	A cytoplasmic part that appears as an electron-dense sphere of around 1.5 micron diameter containing Yb protein found in somatic cells of ovary and testis. There are one to two Yb bodies per cell.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-06-15T05:17:28Z					cellular_component											owl:Class	
GO:0018366	biolink:NamedThing	chiral amino acid racemization	The formation of a mixture of the two possible enantiomers from the D- or L-enantiomer of a chiral amino acid.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0061510	biolink:NamedThing	asymmetric protein localization to new mitotic spindle pole body	Any process in which a protein is transported to, or maintained to the new mitotic spindle pole body resulting in its being distributed asymmetrically.	tmpzr1t_l9r_go_relaxed.owl								dph	2013-02-21T13:49:54Z					biological_process											owl:Class	
GO:0015375	biolink:NamedThing	glycine:sodium symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glycine(out) + Na+(out) = glycine(in) + Na+(in).	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-444120|Reactome:R-HSA-5660840							GO:0015656		molecular_function											owl:Class	
GO:0019938	biolink:NamedThing	peptide cross-linking via N6-(L-isoaspartyl)-L-lysine, presumed catalytic	The formation of isopeptide bonds by ligation of peptidyl-lysine and peptidyl-asparagine residues; occurs in mammals in proteins as yet unidentified by a mechanism probably analogous to that of transglutaminase reactions.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0294							GO:0042266		biological_process											owl:Class	
GO:0003118	biolink:NamedThing	regulation of vasoconstriction by neuronal norepinephrine	Any process that modulates the frequency, rate or extent of reductions in the diameter of blood vessels as a result of norepinephrine released by nerve endings.	tmpzr1t_l9r_go_relaxed.owl	regulation of vasoconstriction by neuronal noradrenaline													biological_process											owl:Class	
GO:0070384	biolink:NamedThing	Harderian gland development	The process whose specific outcome is the progression of the Harderian gland over time, from its formation to the mature structure. The Harderian gland is an anterior orbital structure usually associated with the nictitating membrane, and produces and secretes a variety of substances to the eye, depending upon the species.	tmpzr1t_l9r_go_relaxed.owl						Note that the Harderian gland is found in all terrestrial vertebrate groups, including amphibia, reptiles, birds, and mammals. However, it appears to be absent in certain mammals such as bats, cows, horses, and higher primates. Though largely absent in the adult human, it is present in the fetal and neonatal stages.								biological_process											owl:Class	
GO:1990679	biolink:NamedThing	histone H4-K12 deacetylation	The modification of histone H4 by the removal of an acetyl group from lysine at position 12 of the histone.	tmpzr1t_l9r_go_relaxed.owl								al	2015-03-02T15:40:44Z					biological_process											owl:Class	
GO:0015441	biolink:NamedThing	ABC-type beta-glucan transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + beta-glucan(in) = ADP + phosphate + beta-glucan(out).	tmpzr1t_l9r_go_relaxed.owl	ATPase-coupled beta-glucan transporter activity|beta-glucan-transporting ATPase activity|beta-glucan ABC transporter|ABC-type beta-glucan transporter|ATP-dependent beta-glucan transporter activity				MetaCyc:3.6.3.42-RXN|EC:7.5.2.3|RHEA:18453									molecular_function											owl:Class	
GO:0007164	biolink:NamedThing	establishment of tissue polarity	Coordinated organization of groups of cells in a tissue, such that they all orient to similar coordinates.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0106137	biolink:NamedThing	IkappaB kinase complex binding	Binding to a IkappaB kinase complex.	tmpzr1t_l9r_go_relaxed.owl								hjd	2018-08-15T14:05:10Z					molecular_function											owl:Class	
GO:0046738	biolink:NamedThing	induction of innate immune response in host by virus	The intentional, virally-encoded stimulation of an innate host defense response to viral infection.	tmpzr1t_l9r_go_relaxed.owl	active induction of innate immune response in host by virus|active viral induction of innate immune response in host													biological_process											owl:Class	
GO:0014862	biolink:NamedThing	regulation of skeletal muscle contraction by chemo-mechanical energy conversion	Any process that modulates the frequency, rate or extent of skeletal muscle contraction by regulating force and velocity of shortening. The force of skeletal muscle contraction is produced by acto-myosin interaction processes through formation of cross bridges. The shortening leads to reduction of length of muscle fiber and sarcomeres.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0036383	biolink:NamedThing	3-hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione monooxygenase activity	Catalysis of the reaction: 3-hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione + FMNH2 + O2 = 3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione + FMN + H2O.	tmpzr1t_l9r_go_relaxed.owl					KEGG_REACTION:R09819|MetaCyc:1.14.14.12-RXN|EC:1.14.14.12|RHEA:31731			bf	2013-05-23T11:31:09Z					molecular_function											owl:Class	
GO:0030883	biolink:NamedThing	endogenous lipid antigen binding	Binding to an endogenous cellular lipid antigen.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0035363	biolink:NamedThing	histone locus body	A nuclear body associated with the histone gene locus that is thought to contain all of the factors necessary for histone mRNA transcription and pre-mRNA processing. In Drosophila, U7 snRNP is located in the histone locus body rather than the distinct Cajal body.	tmpzr1t_l9r_go_relaxed.owl	HLB							bf	2010-03-10T10:44:01Z					cellular_component											owl:Class	
GO:0071191	biolink:NamedThing	protocadherin-alpha-v7-protocadherin-gamma-b4 complex	A protein complex that contains the cell adhesion molecules protocadherin-alpha-v7 and protocadherin-gamma-b4, and is involved in the regulation of protein localization to the plasma membrane.	tmpzr1t_l9r_go_relaxed.owl	Pcdha7-Pcdhgb2 complex							mah	2009-11-23T04:30:51Z					cellular_component											owl:Class	
GO:0102432	biolink:NamedThing	quercetin 7-O-methyltransferase activity	Catalysis of the reaction: quercetin-7-olate + S-adenosyl-L-methionine  <=> rhamnetin + S-adenosyl-L-homocysteine.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-13906									molecular_function											owl:Class	
GO:0033879	biolink:NamedThing	acetylajmaline esterase activity	Catalysis of the reactions: 17-O-acetylajmaline + H2O = ajmaline + acetate, and 17-O-acetylnorajmaline + H2O = norajmaline + acetate.	tmpzr1t_l9r_go_relaxed.owl	AAE|17-O-acetylajmaline O-acetylhydrolase activity|acetylajmalan esterase activity|2beta(R)-17-O-acetylajmalan:acetylesterase activity				EC:3.1.1.80|MetaCyc:RXN-8653|MetaCyc:RXN-8652									molecular_function											owl:Class	
GO:0034830	biolink:NamedThing	(2Z)-2,4-dihydroxydec-2-enedioate aldolase activity	Catalysis of the reaction: (2Z)-2,4-dihydroxydec-2-enedioate = pyruvate + 7-oxoheptanoate.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r1174|EC:4.1.3.-									molecular_function											owl:Class	
GO:0047571	biolink:NamedThing	3-oxosteroid 1-dehydrogenase activity	Catalysis of the reaction: a 3-oxosteroid + acceptor = a 3-oxo-D1-steroid + reduced acceptor.	tmpzr1t_l9r_go_relaxed.owl	3-oxosteroid delta1-dehydrogenase activity|3-ketosteroid-1-en-dehydrogenase activity|3-oxosteroid:(acceptor) delta1-oxidoreductase activity|3-ketosteroid-delta1-dehydrogenase activity|1-ene-dehydrogenase activity|4-en-3-oxosteroid:(acceptor)-1-en-oxido-reductase activity|delta1-dehydrogenase activity|delta1-steroid reductase activity|3-oxosteroid:acceptor delta1-oxidoreductase activity|3-oxosteroid:(2,6-dichlorphenolindophenol) delta1-oxidoreductase activity				UM-BBD_enzymeID:e0712|MetaCyc:3-OXOSTEROID-1-DEHYDROGENASE-RXN|EC:1.3.99.4|RHEA:13329									molecular_function											owl:Class	
GO:0044205	biolink:NamedThing	'de novo' UMP biosynthetic process	The chemical reactions and pathways resulting in the formation of UMP, uridine monophosphate, starting with the synthesis of (S)-dihydroorotate from bicarbonate; UMP biosynthesis may either occur via reduction by quinone, NAD(+) or oxygen.	tmpzr1t_l9r_go_relaxed.owl	'de novo' UMP biosynthesis							jl	2009-10-21T11:27:31Z					biological_process											owl:Class	
GO:0052754	biolink:NamedThing	GTP:coenzyme F420 guanyltransferase activity	Catalysis of the reaction: GTP + factor gamma-F420-2 + H+ = coenzyme F390-G + diphosphate.	tmpzr1t_l9r_go_relaxed.owl	coenzyme F390-G synthetase activity|GTP:coenzyme F420 guanylyltransferase activity							ai	2011-09-22T03:25:30Z					molecular_function											owl:Class	
GO:0050528	biolink:NamedThing	acyloxyacyl hydrolase activity	Catalysis of the reaction: 3-(acyloxy)acyl group of bacterial toxin = 3-hydroxyacyl group of bacterial toxin + a fatty acid.	tmpzr1t_l9r_go_relaxed.owl					RHEA:12032|MetaCyc:3.1.1.77-RXN|EC:3.1.1.77									molecular_function											owl:Class	
GO:0120116	biolink:NamedThing	glucagon processing	The formation of mature glucagon by proteolysis of the precursor proglucagon.	tmpzr1t_l9r_go_relaxed.owl								krc	2017-11-08T19:31:42Z					biological_process											owl:Class	
GO:0047438	biolink:NamedThing	2-dehydro-3-deoxy-L-pentonate aldolase activity	Catalysis of the reaction: 2-dehydro-3-deoxy-L-pentonate = glycolaldehyde + pyruvate.	tmpzr1t_l9r_go_relaxed.owl	2-dehydro-3-deoxy-L-pentonate glycolaldehyde-lyase activity|2-keto-3-deoxy-L-arabonate aldolase activity|2-dehydro-3-deoxy-L-pentonate glycolaldehyde-lyase (pyruvate-forming)|3-deoxy-D-pentulosonic acid aldolase|2-keto-3-deoxy-L-pentonate aldolase activity|2-keto-3-deoxy-D-xylonate aldolase activity				RHEA:18545|EC:4.1.2.18|MetaCyc:4.1.2.18-RXN									molecular_function											owl:Class	
GO:0102429	biolink:NamedThing	genistein-3-O-glucoside 1,6-glucosyltransferase activity	Catalysis of the reaction: genistin + UDP-alpha-D-glucose <=> genistin 7-gentiobioside + UDP + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-13831									molecular_function											owl:Class	
GO:1903258	biolink:NamedThing	sorbose import across plasma membrane	The process in which sorbose is transported from outside of a cell, across the plasma membrane and into the cytosol.	tmpzr1t_l9r_go_relaxed.owl	sorbose import into cell							mah	2014-08-06T09:21:53Z					biological_process											owl:Class	
GO:0035525	biolink:NamedThing	NF-kappaB p50/p65 complex	A heterodimer of NF-kappa B p50 and p65 subunits.	tmpzr1t_l9r_go_relaxed.owl	NF-kappa p105/RelA complex|NF-kappa p50/RelA complex|NF-kappa p105/p65 complex|NF-kappa B1/p65 complex|NF-kappa B1/RelA complex					Note that the p50 subunit is encoded by NFKB1 gene in human and the p65 subunit is encoded by the RELA gene in human. Similar nomenclature is used in other vertebrate species. The p50 subunit has a precursor form p105 in some publications.		bf	2010-05-05T10:45:13Z					cellular_component											owl:Class	
GO:0047251	biolink:NamedThing	thiohydroximate beta-D-glucosyltransferase activity	Catalysis of the reaction: phenylthioacetohydroximate + UDP-D-glucose = desulfoglucotropeolin + UDP.	tmpzr1t_l9r_go_relaxed.owl	desulfoglucosinolate-uridine diphosphate glucosyltransferase activity|thiohydroximate S-glucosyltransferase activity|uridine diphosphoglucose-thiohydroximate glucosyltransferase activity|N-hydroxythioamide S-beta-glucosyltransferase activity|UDPG:thiohydroximate glucosyltransferase activity|thiohydroximate glucosyltransferase activity|UDP-glucose:thiohydroximate S-beta-D-glucosyltransferase activity|UDP-glucose:N-hydroxy-2-phenylethanethioamide S-beta-D-glucosyltransferase activity				RHEA:13757|MetaCyc:2.4.1.195-RXN|EC:2.4.1.195									molecular_function											owl:Class	
GO:0004523	biolink:NamedThing	RNA-DNA hybrid ribonuclease activity	Catalysis of the endonucleolytic cleavage of RNA in RNA-DNA hybrids to 5'-phosphomonoesters.	tmpzr1t_l9r_go_relaxed.owl	RNase H activity|ribonuclease H2 activity|endoribonuclease0 H activity|ribonuclease H activity|hybrid ribonuclease activity|endoribonuclease H|RNA*DNA hybrid ribonucleotidohydrolase activity|calf thymus ribonuclease H activity|RNase H3 activity|RNase H2 activity|hybridase (ribonuclease H)|RNase H1 activity|endoribonuclease H (calf thymus)|hybrid nuclease activity|hybridase activity|ribonuclease H3 activity|ribonuclease H1 activity				Reactome:R-HSA-182795|Reactome:R-HSA-173769|EC:3.1.26.4|MetaCyc:3.1.26.4-RXN|Reactome:R-HSA-182859|Reactome:R-HSA-164528|Reactome:R-HSA-164519	Note that the EC recommended name for this enzyme activity is 'calf thymus ribonuclease H', even though it is found in many species.						GO:0004524		molecular_function											owl:Class	
GO:0047088	biolink:NamedThing	dihydrosanguinarine 10-monooxygenase activity	Catalysis of the reaction: dihydrosanguinarine + H(+) + NADPH + O(2) = 10-hydroxydihydrosanguinarine + H(2)O + NADP(+).	tmpzr1t_l9r_go_relaxed.owl	dihydrosanguinarine 10-hydroxylase activity|dihydrosanguinarine,NADPH:oxygen oxidoreductase (10-hydroxylating)				EC:1.14.14.100|KEGG_REACTION:R04702|MetaCyc:1.14.13.56-RXN|RHEA:10528									molecular_function											owl:Class	
GO:0050454	biolink:NamedThing	coenzyme F420 hydrogenase activity	Catalysis of the reaction: coenzyme F420 + H(2) + H(+) = reduced coenzyme F420.	tmpzr1t_l9r_go_relaxed.owl	8-hydroxy-5-deazaflavin-reducing hydrogenase activity|coenzyme F420-dependent hydrogenase activity|F420-reducing hydrogenase activity|hydrogen:coenzyme F420 oxidoreductase activity				KEGG_REACTION:R03025|MetaCyc:COENZYME-F420-HYDROGENASE-RXN|EC:1.12.98.1|RHEA:23760									molecular_function											owl:Class	
GO:0120044	biolink:NamedThing	stereocilium base	The tapered base of the stereocilium adjacent to where it joins the hair cell body. This region contains a rootlet comprised of bundled actin filaments which spans the joint and stabilizes the stereocilium.	tmpzr1t_l9r_go_relaxed.owl	stereocilium taper							krc	2017-05-15T20:45:06Z					cellular_component											owl:Class	
GO:0097395	biolink:NamedThing	response to interleukin-32	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-32 stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to IL-32							pr	2012-10-23T13:21:16Z					biological_process											owl:Class	
GO:0052610	biolink:NamedThing	beta-cryptoxanthin hydroxylase activity	Catalysis of the reaction: beta-cryptoxanthin + a reduced electron acceptor + oxygen = zeaxanthin + an oxidized electron acceptor + H2O.	tmpzr1t_l9r_go_relaxed.owl	carotene beta-ring hydroxylase activity|beta-carotene hydroxylase activity|beta-ring carotenoid 3-hydroxylase activity				MetaCyc:RXN-8026|RHEA:30327									molecular_function											owl:Class	
GO:0050231	biolink:NamedThing	putrescine carbamoyltransferase activity	Catalysis of the reaction: carbamoyl phosphate + putrescine = N-carbamoylputrescine + H(+) + phosphate.	tmpzr1t_l9r_go_relaxed.owl	putrescine transcarbamylase activity|putrescine synthase activity|carbamoyl-phosphate:putrescine carbamoyltransferase activity|PTCase activity				RHEA:21936|KEGG_REACTION:R01399|EC:2.1.3.6|MetaCyc:PUTRESCINE-CARBAMOYLTRANSFERASE-RXN									molecular_function											owl:Class	
GO:0034336	biolink:NamedThing	misfolded RNA binding	Binding to an RNA molecule that has assumed an incorrect conformation.	tmpzr1t_l9r_go_relaxed.owl	RNA chaperone													molecular_function											owl:Class	
GO:0044697	biolink:NamedThing	HICS complex	A multisubunit complex involved in cytokinesis. In the yeast Saccharomyces cerevisiae this complex consists of Sho1p, Hof1p, Inn1p and Cyk3p proteins.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-09-19T13:30:22Z					cellular_component											owl:Class	
GO:0045160	biolink:NamedThing	myosin I complex	A myosin complex containing a class I myosin heavy chain and associated light chains; myosin I heavy chains are single-headed, possess tails of various lengths, and do not self-associate into bipolar filaments; myosin I complexes are involved in diverse processes related to membrane traffic and cell movement.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0097410	biolink:NamedThing	hippocampal interneuron differentiation	The process in which a relatively unspecialized cell acquires specialized features of a hippocampal interneuron.	tmpzr1t_l9r_go_relaxed.owl								pr	2012-11-04T10:58:28Z					biological_process											owl:Class	
GO:1990247	biolink:NamedThing	N6-methyladenosine-containing RNA binding	Binding to an RNA molecule modified by N6-methyladenosine (m6A), a modification present at internal sites of mRNAs and some non-coding RNAs.	tmpzr1t_l9r_go_relaxed.owl								sp	2013-12-04T06:55:29Z					molecular_function											owl:Class	
GO:0018584	biolink:NamedThing	2,4,5-trichlorophenoxyacetic acid oxygenase activity	Catalysis of the reaction: 2,4,5-trichlorophenoxyacetic acid + 1/2 O2 = glyoxylate + 2,4,5-trichlorophenol.	tmpzr1t_l9r_go_relaxed.owl					EC:1.13.99.-|UM-BBD_reactionID:r0359									molecular_function											owl:Class	
GO:1901741	biolink:NamedThing	positive regulation of myoblast fusion	Any process that activates or increases the frequency, rate or extent of myoblast fusion.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of myoblast fusion|activation of myoblast fusion|up regulation of myoblast fusion|upregulation of myoblast fusion							rl	2013-01-11T20:24:03Z					biological_process											owl:Class	
GO:0030731	biolink:NamedThing	guanidinoacetate N-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + guanidinoacetate = S-adenosyl-L-homocysteine + creatine + H(+).	tmpzr1t_l9r_go_relaxed.owl	guanidoacetate methyltransferase activity|guanidinoacetate transmethylase activity|guanidinoacetate methyltransferase activity|methionine-guanidinoacetic transmethylase activity|S-adenosyl-L-methionine:N-guanidinoacetate methyltransferase activity|GA methylpherase activity				RHEA:10656|EC:2.1.1.2|KEGG_REACTION:R01883|MetaCyc:GUANIDINOACETATE-N-METHYLTRANSFERASE-RXN									molecular_function											owl:Class	
GO:0042785	biolink:NamedThing	evasion of host immune response via regulation of host cytokine network	Any mechanism of active immune avoidance which works by regulating host cytokine networks, e.g. by secreting proteins that mimic cytokine receptors that act to sequester host cytokines and inhibit action. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	active immune evasion via modulation of host cytokine network|active evasion of host immune response via regulation of host cytokine network|active immune evasion via regulation of host cytokine network|active evasion of immune response of other organism via regulation of cytokine network of other organism involved in symbiotic interaction											GO:0051812		biological_process											owl:Class	
GO:0072261	biolink:NamedThing	metanephric extraglomerular mesangial cell proliferation involved in metanephros development	The multiplication or reproduction of extraglomerular glomerular mesangium cells in the metanephros by cell division, resulting in the expansion of their population. Extraglomerular mesangial cells (also known as lacis cells, Goormaghtigh cells) are light-staining cells in the kidney found outside the glomerulus, near the vascular pole and macula densa.	tmpzr1t_l9r_go_relaxed.owl	metanephric lacis cell proliferation|metanephric Goormaghtigh proliferation							mah	2010-03-30T02:14:17Z					biological_process											owl:Class	
GO:0048007	biolink:NamedThing	antigen processing and presentation, exogenous lipid antigen via MHC class Ib	The process in which an antigen-presenting cell expresses lipid antigen of exogenous origin in association with an MHC class Ib protein complex on its cell surface. Class Ib here refers to non-classical class I molecules, such as those of the CD1 family.	tmpzr1t_l9r_go_relaxed.owl	antigen presentation, exogenous peptide antigen|exogenous lipid antigen processing and presentation via MHC class Ib													biological_process											owl:Class	
GO:0033752	biolink:NamedThing	acetylacetone-cleaving enzyme activity	Catalysis of the reaction: pentane-2,4-dione + O2 = acetate + 2-oxopropanal.	tmpzr1t_l9r_go_relaxed.owl	acetylacetone-cleaving enzyme|diketone cleaving dioxygenase activity|acetylacetone:oxygen oxidoreductase activity|acetylacetone dioxygenase activity|diketone cleaving enzyme|Dke1				EC:1.13.11.50|RHEA:12877									molecular_function											owl:Class	
GO:0050020	biolink:NamedThing	L-arabinonate dehydratase activity	Catalysis of the reaction: L-arabinonate = 2-dehydro-3-deoxy-L-arabinonate + H(2)O.	tmpzr1t_l9r_go_relaxed.owl	L-arabonate dehydrase activity|L-arabinonate hydro-lyase activity|L-arabinonate hydro-lyase (2-dehydro-3-deoxy-L-arabinonate-forming)|L-arabonate dehydratase activity				KEGG_REACTION:R02522|RHEA:20968|EC:4.2.1.25|MetaCyc:L-ARABINONATE-DEHYDRATASE-RXN									molecular_function											owl:Class	
GO:0050093	biolink:NamedThing	methanol dehydrogenase activity	Catalysis of the reaction: methanol + NAD(+) = formaldehyde + H(+) + NADH.	tmpzr1t_l9r_go_relaxed.owl	methanol:NAD+ oxidoreductase activity				KEGG_REACTION:R00605|RHEA:19401|MetaCyc:METHANOL-DEHYDROGENASE-RXN|EC:1.1.1.244									molecular_function											owl:Class	
GO:0016607	biolink:NamedThing	nuclear speck	A discrete extra-nucleolar subnuclear domain, 20-50 in number, in which splicing factors are seen to be localized by immunofluorescence microscopy.	tmpzr1t_l9r_go_relaxed.owl	nuclear speckle|speckle focus|splicing speckle|nuclear speckles|speckle domain													cellular_component											owl:Class	
GO:0032145	biolink:NamedThing	succinate-semialdehyde dehydrogenase binding	Binding to succinate-semialdehyde dehydrogenase.	tmpzr1t_l9r_go_relaxed.owl	succinic semialdehyde dehydrogenase binding													molecular_function											owl:Class	
GO:0004338	biolink:NamedThing	glucan exo-1,3-beta-glucosidase activity	Catalysis of the successive hydrolysis of beta-D-glucose units from the non-reducing ends of (1->3)-beta-D-glucans, releasing alpha-glucose.	tmpzr1t_l9r_go_relaxed.owl	exo-1,3-beta-glucosidase activity|beta-1,3-glucan exo-hydrolase activity|exo-beta-1,3-glucanase activity|exo-1,3-beta-D-glucanase activity|exo (1->3)-beta-glucanase activity|exo-1,3-beta-glucanase activity|1,3-beta-glucan glucohydrolase activity|exo-beta-(1->3)-D-glucanase activity|exo-beta-(1->3)-glucanohydrolase activity|glucan 1,3-beta-glucosidase activity|exo-beta-1,3-D-glucanase activity				MetaCyc:3.2.1.58-RXN|EC:3.2.1.58									molecular_function											owl:Class	
GO:1901785	biolink:NamedThing	p-cresol catabolic process	The chemical reactions and pathways resulting in the breakdown of p-cresol.	tmpzr1t_l9r_go_relaxed.owl	p-cresol breakdown|p-cresol catabolism|p-cresol degradation							yaf	2013-01-16T11:04:04Z					biological_process											owl:Class	
GO:0033716	biolink:NamedThing	nucleoside oxidase (hydrogen peroxide-forming) activity	Catalysis of the reactions: adenosine + 2 O2 = 9-riburonosyladenine + 2 hydrogen peroxide.	tmpzr1t_l9r_go_relaxed.owl	nucleoside:oxygen 5'-oxidoreductase (hydrogen peroxide-forming) activity				RHEA:15489|EC:1.1.3.39|MetaCyc:1.1.3.39-RXN	Two other reactions might be associated with this activity: (1a) adenosine + O2 = 5'-dehydroadenosine + hydrogen peroxide, and (1b) 5'-dehydroadenosine + O2 = 9-riburonosyladenine + hydrogen peroxide.								molecular_function											owl:Class	
GO:0046669	biolink:NamedThing	regulation of compound eye retinal cell programmed cell death	Any process that modulates the frequency, rate or extent of programmed cell death that occurs in the compound eye retina.	tmpzr1t_l9r_go_relaxed.owl	regulation of retinal cell programmed cell death													biological_process											owl:Class	
GO:0033839	biolink:NamedThing	flavonol-3-O-glycoside glucosyltransferase activity	Catalysis of the reaction: UDP-glucose + a flavonol 3-O-beta-D-glucosyl-(1->2)-beta-D-glucoside = UDP + a flavonol 3-O-beta-D-glucosyl-(1->2)-beta-D-glucosyl-(1->2)-beta-D-glucoside.	tmpzr1t_l9r_go_relaxed.owl	UDP-glucose:flavonol-3-O-beta-D-glucosyl-(1->2)-beta-D-glucoside 2'''-O-beta-D-glucosyltransferase activity				EC:2.4.1.240|MetaCyc:2.4.1.240-RXN|RHEA:23544									molecular_function											owl:Class	
GO:0045301	biolink:NamedThing	tRNA-(2-methylthio-N-6-(cis-hydroxy)isopentenyl adenosine)-hydroxylase activity	Catalysis of the reaction: tRNA-(2-methylthio-N-6-isopentenyl adenosine) = tRNA-(2-methylthio-N-6-(cis-hydroxy)isopentenyl adenosine) + O2. 2-methylthio-N-6-isopentenyl adenosine is also known as ms2i6A; 2-methylthio-N-6-(cis-hydroxy)isopentenyl adenosine is also known as ms2io6A and 2-methylthio-cis-ribozeatin.	tmpzr1t_l9r_go_relaxed.owl	tRNA-(ms2io6A)-hydroxylase activity|tRNA-(2-methylthio-N-6-(cis-hydroxy)isopentenyladenosine)-hydroxylase activity|2-methylthio-cis-ribozeatin hydroxylase activity													molecular_function											owl:Class	
GO:0036198	biolink:NamedThing	dTMP salvage	Any process which produces dTMP, deoxyribosylthymine monophosphate (2'-deoxyribosylthymine 5'-phosphate) without de novo synthesis.	tmpzr1t_l9r_go_relaxed.owl	dTMP biosynthesis via salvage pathway|deoxythymidine monophosphate biosynthesis via salvage pathway				UniPathway:UPA00578			bf	2012-04-20T10:33:28Z					biological_process											owl:Class	
GO:0033231	biolink:NamedThing	carbohydrate export	The directed movement of carbohydrates out of a cell or organelle.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0006934	biolink:NamedThing	substrate-bound cell migration, adhesion receptor recycling	The directed movement of accumulated adhesion components such as integrins from the rear of a migrating cell toward the cell front, where they are available to form new protrusions and adhesions.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1905334	biolink:NamedThing	Swi5-Sfr1 complex binding	Binding to a Swi5-Sfr1 complex.	tmpzr1t_l9r_go_relaxed.owl	Sae3-Mei5 complex binding							al	2016-07-25T16:18:58Z					molecular_function											owl:Class	
GO:0040002	biolink:NamedThing	collagen and cuticulin-based cuticle development	Synthesis and deposition of a collagen and cuticulin-based noncellular, hardened, or membranous secretion from an epithelial sheet. An example of this process is found in Caenorhabditis elegans.	tmpzr1t_l9r_go_relaxed.owl	collagen and cuticulin-based cuticle synthesis|collagen and cuticulin-based cuticle biosynthetic process|collagen and cuticulin-based cuticle formation|collagen and cuticulin-based cuticle anabolism													biological_process											owl:Class	
GO:0032152	biolink:NamedThing	meiotic septin complex	A heterooligomeric septin complex that acts during meiotic cell division.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0018799	biolink:NamedThing	4-hydroxybenzoate decarboxylase activity	Catalysis of the reaction: 4-hydroxybenzoate + H(+) = CO(2) + phenol.	tmpzr1t_l9r_go_relaxed.owl	4-hydroxybenzoate carboxy-lyase activity|p-hydroxybenzoate decarboxylase activity|4-hydroxybenzoate carboxy-lyase (phenol-forming)				UM-BBD_reactionID:r0159|MetaCyc:4-HYDROXYBENZOATE-DECARBOXYLASE-RXN|RHEA:10876|KEGG_REACTION:R01238|EC:4.1.1.61									molecular_function											owl:Class	
GO:0033792	biolink:NamedThing	bile-acid 7alpha-dehydroxylase activity	Catalysis of the reactions: deoxycholate + FAD + H2O = cholate + FADH2, and lithocholate + FAD + H2O = chenodeoxycholate + FADH2.	tmpzr1t_l9r_go_relaxed.owl	7alpha-dehydroxylase activity|cholate 7alpha-dehydroxylase activity|bile acid 7-dehydroxylase activity|deoxycholate:FAD oxidoreductase (7alpha-dehydroxylating) activity|deoxycholate:NAD+ oxidoreductase activity				MetaCyc:RXN-8658|MetaCyc:RXN-8659|EC:1.17.99.5									molecular_function											owl:Class	
GO:0021928	biolink:NamedThing	basket cell precursor proliferation	The multiplication or reproduction of neuroblasts that will give rise to basket cells. A cerebellar basket cell is an inhibitory GABAergic interneuron found in the cerebellar cortex.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0072219	biolink:NamedThing	metanephric cortical collecting duct development	The process whose specific outcome is the progression of the metanephric cortical collecting duct over time, from its formation to the mature structure. The metanephric cortical collecting duct is the portion of the metanephric collecting duct that resides in the renal cortex.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-03-18T03:34:52Z					biological_process											owl:Class	
GO:0000950	biolink:NamedThing	branched-chain amino acid catabolic process to alcohol via Ehrlich pathway	The chemical reactions and pathways involving the catabolism of branched chain amino acids to produce branched chain alcohols with one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. When a branched chain family amino acid, leucine, isoleucine, or valine, is used as the substrate, 3-methylbutanol, 2-methylbutanol, or 2-methylpropanol, respectively, is produced. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of alcohols, often collectively referred to as fusel alcohols. Depending on the redox state of the cells, carboxylic acid derivatives may be produced instead of alcohols.	tmpzr1t_l9r_go_relaxed.owl	branched chain family amino acid catabolic process to alcohol via Ehrlich pathway													biological_process											owl:Class	
GO:0004352	biolink:NamedThing	glutamate dehydrogenase (NAD+) activity	Catalysis of the reaction: L-glutamate + H2O + NAD+ = 2-oxoglutarate + NH3 + NADH + H+.	tmpzr1t_l9r_go_relaxed.owl	glutamic dehydrogenase activity|glutamic acid dehydrogenase|NAD:glutamate oxidoreductase activity|NAD-linked glutamic dehydrogenase activity|NAD-specific glutamate dehydrogenase activity|glutamate dehydrogenase (NAD)|L-glutamate:NAD+ oxidoreductase (deaminating)|NAD-dependent glutamate dehydrogenase activity|NAD-linked glutamate dehydrogenase activity|NAD-specific glutamic dehydrogenase activity|NAD-dependent glutamic dehydrogenase activity|L-glutamate dehydrogenase|NADH-linked glutamate dehydrogenase activity|glutamate oxidoreductase activity|NAD-glutamate dehydrogenase activity				EC:1.4.1.2|MetaCyc:GLUTAMATE-DEHYDROGENASE-RXN|RHEA:15133									molecular_function											owl:Class	
GO:0050639	biolink:NamedThing	10-hydroxytaxane O-acetyltransferase activity	Catalysis of the reaction: 10-desacetyltaxuyunnanin C + acetyl-CoA = CoA + taxuyunnanin C.	tmpzr1t_l9r_go_relaxed.owl	acetyl coenzyme A: 10-hydroxytaxane O-acetyltransferase activity|acetyl-CoA:taxan-10beta-ol O-acetyltransferase|acetyl coenzyme A:10-hydroxytaxane O-acetyltransferase activity				MetaCyc:2.3.1.163-RXN|EC:2.3.1.163|RHEA:18837|KEGG_REACTION:R07252									molecular_function											owl:Class	
GO:0018676	biolink:NamedThing	(S)-limonene 7-monooxygenase activity	Catalysis of the reaction: (4S)-limonene + H(+) + NADPH + O(2) = (4S)-perillyl alcohol + H(2)O + NADP(+).	tmpzr1t_l9r_go_relaxed.owl	(-)-limonene 7-monooxygenase activity				KEGG_REACTION:R02470|RHEA:23432|MetaCyc:--LIMONENE-7-MONOOXYGENASE-RXN|UM-BBD_reactionID:r0728|EC:1.14.14.52									molecular_function											owl:Class	
GO:0046960	biolink:NamedThing	sensitization	An increased in a behavioral response to a repeated stimulus. For example, a shock to the tail of the marine snail Aplysia, to which the snail responds by withdrawing its gill, will result in increased gill withdrawal the next time the skin is touched.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Sensitization									biological_process											owl:Class	
GO:0050593	biolink:NamedThing	N-methylcoclaurine 3'-monooxygenase activity	Catalysis of the reaction: (S)-N-methylcoclaurine + H(+) + NADPH + O(2) = (S)-3'-hydroxy-N-methylcoclaurine + H(2)O + NADP(+).	tmpzr1t_l9r_go_relaxed.owl	N-methylcoclaurine 3'-hydroxylase activity|(S)-N-methylcoclaurine 3'-hydroxylase activity|(S)-N-methylcoclaurine,NADPH:oxygen oxidoreductase (3'-hydroxylating)|cytochrome P450 80B1 activity				KEGG_REACTION:R05732|EC:1.14.14.102|RHEA:16649|MetaCyc:1.14.13.71-RXN									molecular_function											owl:Class	
GO:0034378	biolink:NamedThing	chylomicron assembly	The non-covalent aggregation and arrangement of proteins and lipids in the intestine to form a chylomicron.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0030544	biolink:NamedThing	Hsp70 protein binding	Binding to a Hsp70 protein, heat shock proteins around 70kDa in size.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0031457	biolink:NamedThing	glycine betaine catabolic process	The chemical reactions and pathways resulting in the breakdown of glycine betaine, N-trimethylglycine.	tmpzr1t_l9r_go_relaxed.owl	N-trimethylglycine catabolic process|N-trimethylglycine catabolism|glycine betaine catabolism|glycine betaine degradation|glycine betaine breakdown													biological_process											owl:Class	
GO:0034537	biolink:NamedThing	2-hydroxy-3-methylbenzalpyruvate hydratase-aldolase activity	Catalysis of the reaction: 2-hydroxy-3-methylbenzalpyruvate + H2O = pyruvate + 3-methylsalicylaldehyde.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0783									molecular_function											owl:Class	
GO:0033794	biolink:NamedThing	sarcosine reductase activity	Catalysis of the reaction: acetyl phosphate + methylamine + thioredoxin disulfide = N-methylglycine + phosphate + thioredoxin.	tmpzr1t_l9r_go_relaxed.owl	acetyl-phosphate methylamine:thioredoxin disulfide oxidoreductase (N-methylglycine-forming) activity				RHEA:12825|EC:1.21.4.3									molecular_function											owl:Class	
GO:0019442	biolink:NamedThing	tryptophan catabolic process to acetyl-CoA	The chemical reactions and pathways resulting in the breakdown of tryptophan into other compounds, including acetyl-CoA.	tmpzr1t_l9r_go_relaxed.owl	tryptophan degradation to acetyl-CoA|tryptophan breakdown to acetyl-CoA				MetaCyc:TRYPTOPHAN-DEGRADATION-1									biological_process											owl:Class	
GO:0031563	biolink:NamedThing	mating projection tip polarisome	Protein complex that has a role in determining cell polarity, found at the tip of the mating projection in unicellular fungi exposed to mating pheromone.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0090553	biolink:NamedThing	unicellular trichome tip	A cell projection part that is the apical most portion of a unicellular trichome apex.	tmpzr1t_l9r_go_relaxed.owl								tb	2013-04-25T11:56:56Z					cellular_component											owl:Class	
GO:0008798	biolink:NamedThing	beta-aspartyl-peptidase activity	Catalysis of the cleavage of a beta-linked aspartic residue from the N-terminus of a polypeptide.	tmpzr1t_l9r_go_relaxed.owl	beta-aspartyl dipeptidase activity|beta-aspartyl peptidase activity				EC:3.4.19.5|Reactome:R-HSA-5692495|Reactome:R-HSA-5696365|MetaCyc:3.4.19.5-RXN									molecular_function											owl:Class	
GO:0046715	biolink:NamedThing	active borate transmembrane transporter activity	Enables the transport of borate across a membrane against the concentration gradient.	tmpzr1t_l9r_go_relaxed.owl	borate transmembrane transporter activity|efflux-type boron transporter|borate uptake transmembrane transporter activity|boron transmembrane transporter activity|efflux-type borate transporter|boron uptake transmembrane transporter activity							dhl	2009-05-19T04:09:56Z			GO:0080138		molecular_function											owl:Class	
GO:0051264	biolink:NamedThing	mono-olein transacylation activity	Catalysis of the reaction: mono-olein + mono-olein = diolein + glycerol. Mono-olein, also known as mono-oleoylglycerol, is the monoglyceride formed from oleic acid, 9-octodecenoic acid; diolein is also known as dioleoylglycerol.	tmpzr1t_l9r_go_relaxed.owl	mono-oleoylglycerol O-acyltransferase activity|acyl-CoA-independent mono-olein transacylation|MOG transacylation|monoolein transacylation|mono-oleoylglycerol transacylase activity|monooleoylglycerol transacylase activity|monooleoylglycerol O-acyltransferase activity													molecular_function											owl:Class	
GO:0080078	biolink:NamedThing	tricaffeoyl spermidine:S-adenosyl-L-methionine O-methyltransferase activity	Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to the oxygen atom of a tricaffeoyl spermidine molecule.	tmpzr1t_l9r_go_relaxed.owl								dhl	2009-04-14T04:01:25Z					molecular_function											owl:Class	
GO:0044201	biolink:NamedThing	host cell nuclear inner membrane	The inner, i.e. lumen-facing, lipid bilayer of the host nuclear envelope.	tmpzr1t_l9r_go_relaxed.owl								jl	2009-10-21T11:08:33Z					cellular_component											owl:Class	
GO:1990888	biolink:NamedThing	2-polyprenyl-6-hydroxyphenol O-methyltransferase activity	Catalysis of the reaction: 2-polyprenyl-6-hydroxyphenol + S-adenosyl-L-methionine = 2-polyprenyl-6-methoxyphenol + S-adenosyl-L-homocysteine + H+.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-10-28T22:31:13Z					molecular_function											owl:Class	
GO:0102874	biolink:NamedThing	1-16:0-2-18:2-digalactosyldiacylglycerol desaturase activity	Catalysis of the reaction: 1-16:0-2-18:2-digalactosyldiacylglycerol + O2 + a reduced electron acceptor <=> 1-16:0-2-18:3-digalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor.	tmpzr1t_l9r_go_relaxed.owl					EC:1.14.19.35|MetaCyc:RXN-8365									molecular_function											owl:Class	
GO:0106136	biolink:NamedThing	lectin-induced modified bacterial internalization	The process in which an organism effects a change in the structure or function of a symbiont organism, mediated by secretion of lectins which bind to the bacterial surface. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	LIMBI							hjd	2018-08-09T17:27:18Z					biological_process											owl:Class	
GO:0018405	biolink:NamedThing	protein-keratan sulfate linkage via keratan sulfate D-glucuronyl-D-galactosyl-D-galactosyl-D-xylosyl-L-threonine	Keratan sulfate components are covalently linked to a core glycoprotein via O-glycosidic linkages between xylose and threonine residues.	tmpzr1t_l9r_go_relaxed.owl	protein-keratan sulphate linkage via keratan sulphate D-glucuronyl-D-galactosyl-D-galactosyl-D-xylosyl-L-threonine				RESID:AA0247									biological_process											owl:Class	
GO:0072728	biolink:NamedThing	response to Gentian violet	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a Gentian violet stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to crystal violet|response to {4-[Bis-(4-dimethylamino-phenyl)-methylene]-cyclohexa-2,5-dienylidene}-dimethyl-ammonium chloride							mah	2012-05-31T11:23:25Z					biological_process											owl:Class	
GO:0033880	biolink:NamedThing	phenylacetyl-CoA hydrolase activity	Catalysis of the reaction: H(2)O + phenylglyoxylyl-CoA = CoA + H(+) + phenylglyoxylate.	tmpzr1t_l9r_go_relaxed.owl	phenylglyoxylyl-CoA hydrolase activity				RHEA:15337|MetaCyc:3.1.2.25-RXN|EC:3.1.2.25|KEGG_REACTION:R07294									molecular_function											owl:Class	
GO:0047013	biolink:NamedThing	cholate 12-alpha dehydrogenase activity	Catalysis of the reaction: cholate + NADP(+) = 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanate + H(+) + NADPH.	tmpzr1t_l9r_go_relaxed.owl	12alpha-hydroxysteroid:NADP+ 12-oxidoreductase activity|12alpha-hydroxysteroid dehydrogenase activity|NAD-dependent 12alpha-hydroxysteroid dehydrogenase activity|12alpha-hydroxy steroid dehydrogenase activity|12-alpha-hydroxysteroid dehydrogenase activity|NADP-12alpha-hydroxysteroid dehydrogenase activity				RHEA:14129|MetaCyc:1.1.1.176-RXN|KEGG_REACTION:R02793|EC:1.1.1.176									molecular_function											owl:Class	
GO:0047975	biolink:NamedThing	guanosine phosphorylase activity	Catalysis of the reaction: guanosine + phosphate = guanine + D-ribose 1-phosphate.	tmpzr1t_l9r_go_relaxed.owl	guanosine:phosphate D-ribosyltransferase activity|guanosine:phosphate alpha-D-ribosyltransferase activity				RHEA:13233|MetaCyc:GUANPHOSPHOR-RXN|EC:2.4.2.15									molecular_function											owl:Class	
GO:0030742	biolink:NamedThing	GTP-dependent protein binding	Binding to a protein or protein complex when at least one of the interacting partners is in the GTP-bound state.	tmpzr1t_l9r_go_relaxed.owl						This term may be used to annotate both partners in a GTP-dependent binding interaction, both the GTP-bound protein and the protein(s) which interact with it.								molecular_function											owl:Class	
GO:0052819	biolink:NamedThing	heteroglycan 2-alpha-mannosyltransferase activity	Catalysis of the reaction: heteroglycan + GDP-mannose = (1->2)-alpha-D-mannosylheteroglycan + GDP.	tmpzr1t_l9r_go_relaxed.owl	GDP-mannose:heteroglycan 2-alpha-D-mannosyltransferase activity|guanosine diphosphomannose-heteroglycan 2-alpha-mannosyltransferase activity|GDP mannose 2-alpha-mannosyltransferase activity|heteropolysaccharide 2-alpha-mannosyltransferase activity				KEGG_REACTION:R03768|EC:2.4.1.48|MetaCyc:2.4.1.48-RXN			ai	2011-10-27T12:36:19Z					molecular_function											owl:Class	
GO:0140393	biolink:NamedThing	norsolorinic acid ketoreductase activity	Catalysis of the reaction: (1'S)-averantin + NADP(+) <=> norsolorinic acid + NADPH.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-9480|RHEA:35447|KEGG_REACTION:R10309|EC:1.1.1.349			pg	2019-11-28T14:38:12Z					molecular_function											owl:Class	
GO:0045703	biolink:NamedThing	ketoreductase activity	Catalysis of the reduction of a ketone group to form the corresponding alcohol.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0050183	biolink:NamedThing	phosphatidylcholine 12-monooxygenase activity	Catalysis of the reaction: 1-acyl-2-oleoyl-sn-glycero-3-phosphocholine + H(+) + NADH + O(2) = 1-acyl-2-[(S)-12-hydroxyoleoyl]-sn-glycero-3-phosphocholine + H(2)O + NAD(+).	tmpzr1t_l9r_go_relaxed.owl	1-acyl-2-oleoyl-sn-glycero-3-phosphocholine,NADH:oxygen oxidoreductase (12-hydroxylating)|oleate delta12-hydroxylase activity|oleate D12-hydroxylase activity|oleate delta12-monooxygenase activity|ricinoleic acid synthase activity|oleate Delta(12)-hydroxylase activity				EC:1.14.18.4|MetaCyc:PHOSPHATIDYLCHOLINE-12-MONOOXYGENASE-RXN|KEGG_REACTION:R03476|RHEA:46360									molecular_function											owl:Class	
GO:0034954	biolink:NamedThing	diphenyl ether 2,3-dioxygenase activity	Catalysis of the reaction: diphenyl ether + O2 = 2,3-dihydroxydiphenyl ether.	tmpzr1t_l9r_go_relaxed.owl					EC:1.14.12.-|UM-BBD_reactionID:r1450									molecular_function											owl:Class	
GO:0034837	biolink:NamedThing	2-mercaptobenzothiazole-cis-6,7-dihydrodiol dehydrogenase activity	Catalysis of the reaction: 2-mercaptobenzothiazole-cis-6,7-dihydrodiol = 6,7-dihydroxy-2-mercaptobenzothiazole + 2 H+ + 2 e-.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r1179									molecular_function											owl:Class	
GO:0031462	biolink:NamedThing	Cul2-RING ubiquitin ligase complex	A ubiquitin ligase complex in which a cullin from the Cul2 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by an elongin-BC adaptor and a SOCS/BC box protein.	tmpzr1t_l9r_go_relaxed.owl	VBC complex|cullin-RING ligase 2|CDL2 complex|CBC complex|CRL2 complex|SCF2 complex|EC2S complex|ECS complex													cellular_component											owl:Class	
GO:0036191	biolink:NamedThing	indolin-2-one monooxygenase activity	Catalysis of the reaction: indolin-2-one + NAD(P)H + H+ + O2 = 3-hydroxyindolin-2-one + NAD(P)+ + H2O.	tmpzr1t_l9r_go_relaxed.owl	indolin-2-one,NAD(P)H:oxygen oxidoreductase (3-hydroxylating)				EC:1.14.14.157|RHEA:31919|KEGG_REACTION:R07421			bf	2012-04-19T11:38:01Z					molecular_function											owl:Class	
GO:0019559	biolink:NamedThing	histidine catabolic process to imidazol-5-yl-lactate	The chemical reactions and pathways resulting in the breakdown of histidine into other compounds, including imidazol-5-yl-lactate.	tmpzr1t_l9r_go_relaxed.owl	histidine breakdown to imidazol-5-yl-lactate|histidine degradation to imidazol-5-yl-lactate				MetaCyc:HISTDEG-PWY									biological_process											owl:Class	
GO:0070557	biolink:NamedThing	PCNA-p21 complex	A protein complex that contains the cyclin-dependent protein kinase inhibitor p21WAF1/CIP1 bound to PCNA; formation of the complex inhibits DNA replication.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0102970	biolink:NamedThing	7-deoxyloganetic acid glucosyltransferase activity	Catalysis of the reaction: UDP-alpha-D-glucose + 7-deoxyloganetate <=> H+ + 7-deoxyloganate + UDP.	tmpzr1t_l9r_go_relaxed.owl					RHEA:39895|EC:2.4.1.323|MetaCyc:RXN-9372									molecular_function											owl:Class	
GO:0061069	biolink:NamedThing	male urethra development	The progression of the male urethra over time from its initial formation to the mature structure. The male urethra is a renal system organ that carries urine from the bladder through the penis to outside the body.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-03-12T08:28:19Z					biological_process											owl:Class	
GO:0062180	biolink:NamedThing	25-hydroxycholecalciferol-23-hydroxylase activity	Catalysis of the reaction: calcidiol + 2 H(+) + O2 + 2 reduced [adrenodoxin] = (23S)-23,25-dihydroxycalciol + H2O + 2 oxidized [adrenodoxin].	tmpzr1t_l9r_go_relaxed.owl					RHEA:46616			dph	2019-11-26T17:12:22Z					molecular_function											owl:Class	
GO:0036001	biolink:NamedThing	'de novo' pyridoxal 5'-phosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of pyridoxal 5'-phosphate, the active form of vitamin B6, from simpler components.	tmpzr1t_l9r_go_relaxed.owl	'de novo' pyridoxal 5'-phosphate formation|'de novo' pyridoxal 5'-phosphate anabolism|'de novo' pyridoxal phosphate biosynthetic process|'de novo' pyridoxal 5'-phosphate synthesis|'de novo' PLP biosynthesis|'de novo' pyridoxal 5'-phosphate biosynthesis				MetaCyc:PYRIDOXSYN-PWY			bf	2011-09-06T02:04:53Z					biological_process											owl:Class	
GO:0080105	biolink:NamedThing	6-methylthiopropyl glucosinolate S-oxygenase activity	Catalysis of the reaction: 6-methylthiopropyl-glucosinolate = 6-methylsulfinylpropyl-glucosinolate.	tmpzr1t_l9r_go_relaxed.owl								dhl	2009-04-23T04:28:55Z					molecular_function											owl:Class	
GO:0102093	biolink:NamedThing	acrylate:acyl-coA CoA transferase activity	Catalysis of the reaction: acryloyl-CoA + H2O <=> acrylate + coenzyme A + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-10985									molecular_function											owl:Class	
GO:0033498	biolink:NamedThing	galactose catabolic process via D-galactonate	The chemical reactions and pathways resulting in the breakdown of galactose, via the intermediate D-galactonate.	tmpzr1t_l9r_go_relaxed.owl	galactose breakdown via D-galactonate|galactose catabolism via D-galactonate|galactose degradation via D-galactonate				MetaCyc:GALDEG-PWY									biological_process											owl:Class	
GO:0019603	biolink:NamedThing	toluene oxidation via 4-hydroxytoluene	The degradation of toluene to form p-hydroxybenzoate; the first step in the pathway is the oxidation of toluene to form 4-hydroxytoluene (4-cresol).	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:TOLUENE-DEG-4-OH-PWY									biological_process											owl:Class	
GO:0019251	biolink:NamedThing	anaerobic cobalamin biosynthetic process	The chemical reactions and pathways resulting in the formation of cobalamin (vitamin B12) in the absence of oxygen.	tmpzr1t_l9r_go_relaxed.owl	anaerobic vitamin B12 biosynthesis|vitamin B12 biosynthesis, anaerobic|vitamin B12 biosynthetic process, anaerobic|anaerobic vitamin B12 biosynthetic process|anaerobic cobalamin formation|anaerobic cobalamin biosynthesis|anaerobic cobalamin anabolism|cobalamin biosynthetic process, anaerobic|cobalamin biosynthesis, anaerobic|anaerobic cobalamin synthesis				MetaCyc:COBALSYN-PWY									biological_process											owl:Class	
GO:0140376	biolink:NamedThing	innate immune receptor activity	Receiving a signal and transmitting it in a cell to initiate an innate immune response.	tmpzr1t_l9r_go_relaxed.owl								pg	2019-10-18T14:21:28Z					molecular_function											owl:Class	
GO:0061158	biolink:NamedThing	3'-UTR-mediated mRNA destabilization	An mRNA destabilization process in which one or more RNA-binding proteins associate with the 3'-untranslated region (UTR) of an mRNA.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-06-22T08:44:39Z					biological_process											owl:Class	
GO:1904613	biolink:NamedThing	cellular response to 2,3,7,8-tetrachlorodibenzodioxine	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 2,3,7,8-tetrachlorodibenzodioxine stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to dioxin|cellular response to TCDD							sl	2015-08-27T19:01:58Z					biological_process											owl:Class	
GO:0043335	biolink:NamedThing	protein unfolding	The process of assisting in the disassembly of non-covalent linkages in a protein or protein aggregate, often where the proteins are in a non-functional or denatured state.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0004780	biolink:NamedThing	sulfate adenylyltransferase (ADP) activity	Catalysis of the reaction: ADP + H(+) + sulfate = 5'-adenylyl sulfate + phosphate.	tmpzr1t_l9r_go_relaxed.owl	ADP:sulfate adenylyltransferase activity|adenosine diphosphate sulfurylase activity|sulphate adenylyltransferase (ADP) activity|sulfate (adenosine diphosphate) adenylyltransferase activity|ADP-sulfurylase activity				EC:2.7.7.5|RHEA:16529|MetaCyc:SULFATE-ADENYLYLTRANSFERASE-ADP-RXN|KEGG_REACTION:R00530									molecular_function											owl:Class	
GO:0103032	biolink:NamedThing	tartronate semialdehyde reductase activity	Catalysis of the reaction: D-glycerate + NAD <=> H+ + 2-hydroxy-3-oxopropanoate + NADH.	tmpzr1t_l9r_go_relaxed.owl					RHEA:18845|MetaCyc:RXN0-5289									molecular_function											owl:Class	
GO:0102669	biolink:NamedThing	isoflavone-7-O-glucoside beta-glucosidase activity	Catalysis of the reaction: daidzein 7-O-beta-D-glucoside + H2O <=> daidzein + beta-D-glucose.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-3591									molecular_function											owl:Class	
GO:0061758	biolink:NamedThing	2-hydroxyglutarate dehydrogenase activity, forward reaction	Catalysis of the reaction: (S)-2-hydroxyglutarate + acceptor -> 2-oxoglutarate + reduced acceptor.	tmpzr1t_l9r_go_relaxed.owl	alpha-ketoglutarate reductase activity, reverse reaction				RHEA:21253			dph	2016-03-07T08:28:58Z					molecular_function											owl:Class	
GO:0016231	biolink:NamedThing	beta-N-acetylglucosaminidase activity	Catalysis of the hydrolysis of terminal non-reducing N-acetyl-D-glucosamine residues in N-acetyl-beta-D-glucosaminides.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0010274	biolink:NamedThing	hydrotropism	Growth or movement in a sessile organism toward or away from water, as of the roots of a plant.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Hydrotropism									biological_process											owl:Class	
GO:0019254	biolink:NamedThing	carnitine metabolic process, CoA-linked	The chemical reactions and pathways involving carnitine, where metabolism is linked to CoA.	tmpzr1t_l9r_go_relaxed.owl	carnitine metabolism, CoA-linked				MetaCyc:CARNMET-PWY									biological_process											owl:Class	
GO:0052823	biolink:NamedThing	2-hydroxy-6-oxonona-2,4,7-trienedioate hydrolase activity	Catalysis of the reaction: (2E,4Z,7E)-2-hydroxy-6-oxonona-2,4,7-trienedioate + H2O = (2E)-2-hydroxypenta-2,4-dienoate + fumarate + H+.	tmpzr1t_l9r_go_relaxed.owl	2-hydroxy-6-ketonona-2,4,7-trienedoic acid hydrolase activity|(2E,4Z,7E)-2-hydroxy-6-oxonona-2,4,7-trienedioate fumarylhydrolase activity				EC:3.7.1.14|MetaCyc:RXN-12070|UM-BBD_reactionID:r1622|RHEA:25046			ai	2011-10-28T03:28:37Z					molecular_function											owl:Class	
GO:1902200	biolink:NamedThing	3-methylbut-2-enoyl-CoA(4-) biosynthetic process	The chemical reactions and pathways resulting in the formation of 3-methylbut-2-enoyl-CoA(4-).	tmpzr1t_l9r_go_relaxed.owl	3-methylbut-2-enoyl-CoA(4-) formation|3-methylbut-2-enoyl-CoA(4-) anabolism|3-methylbut-2-enoyl-CoA(4-) synthesis|3-methylbut-2-enoyl-CoA(4-) biosynthesis							ms	2013-06-06T09:56:21Z					biological_process											owl:Class	
GO:0021963	biolink:NamedThing	spinothalamic tract morphogenesis	Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the spinal cord towards target cells in the thalamus. This axonal process is a member of those that make up the spinothalamic tract, one of the major routes of nociceptive signaling.	tmpzr1t_l9r_go_relaxed.owl	dorsolateral tract of Lissauer morphogenesis													biological_process											owl:Class	
GO:0018521	biolink:NamedThing	1,2-dihydroxy-6-methylcyclohexa-3,5-dienecarboxylate dehydrogenase activity	Catalysis of the reaction: 1,6-dihydroxy-2-methylcyclohexa-2,4-dienecarboxylate + NAD(+) = 3-methylcatechol + CO(2) + NADH.	tmpzr1t_l9r_go_relaxed.owl	1,2-dihydroxy-6-methylcyclohexa-3,5-dienecarboxylate:NAD+ oxidoreductase (decarboxylating)				MetaCyc:1.3.1.68-RXN|RHEA:15657|EC:1.3.1.68|UM-BBD_reactionID:r0224|KEGG_REACTION:R05314									molecular_function											owl:Class	
GO:0050697	biolink:NamedThing	1,1,2-trichloroethene reductive dehalogenase activity	Catalysis of the reaction: trichloroethene + 2 H+ + 2 e- = HCl + 1,2-dichloroethene.	tmpzr1t_l9r_go_relaxed.owl	TCE-reductive dehalogenase activity|1,1,2-trichloroethylene reductive dehalogenase activity				MetaCyc:TCEREDCHLOR-RXN|UM-BBD_enzymeID:e0271									molecular_function											owl:Class	
GO:0047072	biolink:NamedThing	2,3-dihydroxybenzoate 2,3-dioxygenase activity	Catalysis of the reaction: 2,3-dihydroxybenzoate + O(2) = 2-carboxy-cis,cis-muconate + 2 H(+).	tmpzr1t_l9r_go_relaxed.owl	2,3-dihydroxybenzoate 2,3-oxygenase activity|2,3-dihydroxybenzoate:oxygen 2,3-oxidoreductase (decyclizing)				KEGG_REACTION:R01506|RHEA:15369|EC:1.13.11.28|MetaCyc:1.13.11.28-RXN									molecular_function											owl:Class	
GO:0051202	biolink:NamedThing	phytochromobilin metabolic process	The chemical reactions and pathways involving phytochromobilin, the linear tetrapyrrole chromophore required for plant phytochrome photoactivity.	tmpzr1t_l9r_go_relaxed.owl	phytochromobilin metabolism													biological_process											owl:Class	
GO:0030526	biolink:NamedThing	granulocyte macrophage colony-stimulating factor receptor complex	The heterodimeric receptor for granulocyte macrophage colony-stimulating factor.	tmpzr1t_l9r_go_relaxed.owl	granulocyte macrophage colony stimulating factor receptor complex|GM-CSF receptor complex													cellular_component											owl:Class	
GO:0103008	biolink:NamedThing	4-chloro-2-methylphenoxyacetate oxygenase activity	Catalysis of the reaction: 4-chloro-2-methylphenoxyacetate + 2-oxoglutarate + O2 <=> 4-chloro-2-methylphenol + 2-oxo monocarboxylic acid anion + succinate + carbon dioxide.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-9864									molecular_function											owl:Class	
GO:0033934	biolink:NamedThing	glucan 1,4-alpha-maltotriohydrolase activity	Catalysis of the hydrolysis of (1->4)-alpha-D-glucosidic linkages in amylaceous polysaccharides, to remove successive maltotriose residues from the non-reducing chain ends.	tmpzr1t_l9r_go_relaxed.owl	exo-maltotriohydrolase activity|1,4-alpha-D-glucan maltotriohydrolase activity|maltotriohydrolase activity				EC:3.2.1.116|MetaCyc:3.2.1.116-RXN									molecular_function											owl:Class	
GO:0044286	biolink:NamedThing	peg and socket contact	A cell-cell contact zone that consists of membrane invaginations extending from either cell, which contain tight-, gap-, and adherens junctions. Peg and socket contacts form between endothelial cells and pericytes, and between lens fiber cells.	tmpzr1t_l9r_go_relaxed.owl	ball and socket contact				NIF_Subcellular:sao1943947957			jl	2010-02-02T10:15:27Z					cellular_component											owl:Class	
GO:0034877	biolink:NamedThing	isonicotinate dehydrogenase activity	Catalysis of the reaction: isonicotinate + acceptor + H2O = 2-hydroxyisonicotinate + reduced acceptor.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r1337									molecular_function											owl:Class	
GO:0061670	biolink:NamedThing	evoked neurotransmitter secretion	Neurotransmitter secretion that occurs in the presence of the action of a secretagogue or a presynaptic action potential.	tmpzr1t_l9r_go_relaxed.owl	stimulus-dependant neurotransmitter secretion							dph	2014-11-17T08:06:21Z					biological_process											owl:Class	
GO:0033705	biolink:NamedThing	GDP-4-dehydro-6-deoxy-D-mannose reductase activity	Catalysis of the reaction: GDP-6-deoxy-D-mannose + NAD(P)+ = GDP-4-dehydro-6-deoxy-D-mannose + NAD(P)H + H+.	tmpzr1t_l9r_go_relaxed.owl	Rmd|GDP-6-deoxy-D-mannose:NAD(P)+ 4-oxidoreductase (D-rhamnose-forming) activity|GDP-4-keto-6-deoxy-D-mannose reductase activity|GDP-6-deoxy-D-lyxo-4-hexulose reductase activity				EC:1.1.1.281|MetaCyc:GDP-4-DEHYDRO-D-RHAMNOSE-REDUCTASE-RXN	Note that this enzyme differs from EC:1.1.1.187, GDP-4-dehydro-D-rhamnose reductase, in that the only product formed is GDP-D-rhamnose (GDP-6-deoxy-D-mannose).								molecular_function											owl:Class	
GO:0019681	biolink:NamedThing	acetyl-CoA assimilation pathway	The pathways by which acetyl-CoA is processed and converted into alpha-ketoglutarate (2-oxoglutarate); methanogenic archaea use these pathways to assimilate acetyl-CoA into the cell.	tmpzr1t_l9r_go_relaxed.owl	acetyl-CoA catabolic process to alpha-ketoglutarate|acetyl-CoA catabolic process to alpha-oxoglutarate|acetyl-CoA catabolism to alpha-oxoglutarate|acetyl-CoA catabolic process to 2-ketoglutarate|acetyl-CoA catabolism to 2-ketoglutarate|acetyl-CoA catabolism to 2-oxoglutarate|acetyl-CoA catabolism to alpha-ketoglutarate|acetyl-CoA catabolic process to 2-oxoglutarate													biological_process											owl:Class	
GO:0102460	biolink:NamedThing	kaempferol 3-gentiobioside 7-O-rhamnosyltransferase activity	Catalysis of the reaction: kaempferol-3-gentiobioside + UDP-L-rhamnose = H+ + kaempferol-3-O-gentiobioside-7-O-rhamnoside + UDP.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-14008									molecular_function											owl:Class	
GO:0047781	biolink:NamedThing	citrullinase activity	Catalysis of the reaction: H2O + citrulline = NH3 + CO2 + L-ornithine.	tmpzr1t_l9r_go_relaxed.owl	citrulline ureidase activity|L-citrulline 5-N-carbamoyldihydrolase activity|L-citrulline N5-carbamoyldihydrolase activity|citrulline hydrolase activity				RHEA:11940|MetaCyc:CITRULLINASE-RXN|EC:3.5.1.20									molecular_function											owl:Class	
GO:0031926	biolink:NamedThing	pyridoxal phosphate transmembrane transporter activity	Enables the transfer of pyridoxal phosphate from one side of a membrane to the other. Pyridoxal phosphate is pyridoxal phosphorylated at the hydroxymethyl group of C-5, and is the active form of vitamin B6.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0070060	biolink:NamedThing	'de novo' actin filament nucleation	The actin nucleation process in which actin monomers combine in the absence of any existing actin filaments; elongation of the actin oligomer formed by nucleation leads to the formation of an unbranched filament.	tmpzr1t_l9r_go_relaxed.owl	unbranched actin filament nucleation|formin-mediated actin filament nucleation													biological_process											owl:Class	
GO:0034834	biolink:NamedThing	2-mercaptobenzothiazole dioxygenase activity	Catalysis of the reaction: 2-mercaptobenzothiazole + O2 + 2 H+ + 2 e- = 2-mercaptobenzothiazole-cis-6,7-dihydrodiol.	tmpzr1t_l9r_go_relaxed.owl					EC:1.13.11.-|UM-BBD_reactionID:r1177									molecular_function											owl:Class	
GO:1990640	biolink:NamedThing	inositol-2,4,5-triphosphate 5-phosphatase activity	Catalysis of the reaction: 1D-myo-inositol 2,4,5-trisphosphate + H2O = 1D-myo-inositol 2,4-bisphosphate + phosphate.	tmpzr1t_l9r_go_relaxed.owl								al	2015-02-11T18:20:40Z					molecular_function											owl:Class	
GO:0018408	biolink:NamedThing	peptidyl-thyronine iodination to form 3',3'',5',5''-tetraiodo-L-thyronine	The iodination of peptidyl-thyronine to form peptidyl-3',3'',5',5''-tetraiodo-L-thyronine (L-thyroxine).	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0178									biological_process											owl:Class	
GO:1905329	biolink:NamedThing	sphingoid long-chain base transport	The directed movement of a sphingoid long-chain base, sometimes referred to as long-chain base, or sphingoid base, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Sphingoid long-chain bases are long-chain aliphatic amines that are the fundamental building blocks of sphingolipids. The main mammalian sphingoid long-chain bases are dihydrosphingosine and sphingosine, while dihydrosphingosine and phytosphingosine are the main sphingoid long-chain bases in yeast.	tmpzr1t_l9r_go_relaxed.owl	long-chain base transport|dihydrosphingosine transport|sphingoid base(1+) transport|sphingoid transport|sphingosine transport|phytosphingosine transport							tb	2016-07-22T01:40:59Z					biological_process											owl:Class	
GO:1905108	biolink:NamedThing	guanosine binding	Binding to guanosine.	tmpzr1t_l9r_go_relaxed.owl								al	2016-04-05T08:30:47Z					molecular_function											owl:Class	
GO:0018751	biolink:NamedThing	3,5-dichlorophenylcarboximide hydrolase activity	Catalysis of the reaction: 3,5-dichlorophenylcarboximide + OH- = (3,5-dichlorophenylurea)acetate.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0707									molecular_function											owl:Class	
GO:0099615	biolink:NamedThing	(D)-2-hydroxyglutarate-pyruvate transhydrogenase activity	Catalysis of the reaction: (R)-2-hydroxyglutarate + pyruvate = alpha-ketoglutarate + D-lactate, with FAD functioning as an intermediate hydrogen acceptor.	tmpzr1t_l9r_go_relaxed.owl	D-2HG-pyruvate transhydrogenase activity|R-2-hydroxyglutarate alpha-pyruvate transhydrogenase activity													molecular_function											owl:Class	
GO:0060155	biolink:NamedThing	platelet dense granule organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a platelet dense granule. A platelet dense granule is an electron-dense granule occurring in blood platelets that stores and secretes adenosine nucleotides and serotonin. They contain a highly condensed core consisting of serotonin, histamine, calcium, magnesium, ATP, ADP, pyrophosphate and membrane lysosomal proteins.	tmpzr1t_l9r_go_relaxed.owl	platelet dense body organization and biogenesis|platelet dense granule organization and biogenesis|bull's eye body organization and biogenesis|platelet dense granule organisation													biological_process											owl:Class	
GO:0061754	biolink:NamedThing	negative regulation of circulating fibrinogen levels	Any process that reduces the quantity of fibrinogen circulating in the bloodstream.	tmpzr1t_l9r_go_relaxed.owl								dph	2016-02-29T16:19:09Z					biological_process											owl:Class	
GO:0034927	biolink:NamedThing	pyrene 1,2-monooxygenase activity	Catalysis of the reaction: pyrene + O2 + 2 H+ + 2 e- = pyrene-1,2-oxide + H2O.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0943									molecular_function											owl:Class	
GO:0004146	biolink:NamedThing	dihydrofolate reductase activity	Catalysis of the reaction: 5,6,7,8-tetrahydrofolate + NADP+ = 7,8-dihydrofolate + NADPH + H+.	tmpzr1t_l9r_go_relaxed.owl	pteridine reductase:dihydrofolate reductase activity|folic reductase activity|7,8-dihydrofolate reductase activity|dihydrofolate reductase:thymidylate synthase activity|5,6,7,8-tetrahydrofolate:NADP+ oxidoreductase activity|dihydrofolate reduction|dihydrofolic reductase activity|folic acid reductase activity|tetrahydrofolate dehydrogenase activity|NADPH-dihydrofolate reductase activity|DHFR|thymidylate synthetase-dihydrofolate reductase activity|dihydrofolic acid reductase activity				RHEA:15009|EC:1.5.1.3|Reactome:R-HSA-1497794|MetaCyc:DIHYDROFOLATEREDUCT-RXN									molecular_function											owl:Class	
GO:0019422	biolink:NamedThing	disproportionation of elemental sulfur	The process in which sulfur compounds with an intermediate oxidation state serve as both electron donors and electron acceptors in an energy-generating redox process. The reaction takes place anaerobically, in light and in the absence of CO2.	tmpzr1t_l9r_go_relaxed.owl	disproportionation of elemental sulphur				MetaCyc:P203-PWY									biological_process											owl:Class	
GO:1902097	biolink:NamedThing	positive regulation of transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacterium	Any positive regulation of transcription from RNA polymerase II promoter that is involved in defense response to Gram-negative bacterium.	tmpzr1t_l9r_go_relaxed.owl	upregulation of transcription from RNA polymerase II promoter involved in defence response to Gram-negative bacteria|activation of global transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacterium|up-regulation of transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacterium|upregulation of global transcription from RNA polymerase II promoter involved in defence response to Gram-negative bacteria|positive regulation of global transcription from Pol II promoter involved in defence response to Gram-negative bacterium|up-regulation of global transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacteria|positive regulation of transcription from RNA polymerase II promoter involved in defence response to Gram-negative bacteria|activation of transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacteria|activation of global transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacteria|upregulation of global transcription from RNA polymerase II promoter involved in Gram-negative antibacterial peptide activity|positive regulation of transcription from RNA polymerase II promoter involved in Gram-negative antibacterial peptide activity|positive regulation of gene-specific transcription from RNA polymerase II promoter involved in defence response to Gram-negative bacteria|positive regulation of gene-specific transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacteria|positive regulation of transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacteria|activation of transcription from RNA polymerase II promoter involved in defence response to Gram-negative bacteria|up-regulation of global transcription from RNA polymerase II promoter involved in defence response to Gram-negative bacterium|stimulation of global transcription from RNA polymerase II promoter involved in defence response to Gram-negative bacterium|upregulation of global transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacteria|up-regulation of transcription from RNA polymerase II promoter involved in Gram-negative antibacterial peptide activity|upregulation of global transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacterium|stimulation of transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacteria|positive regulation of gene-specific transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacterium|stimulation of transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacterium|up-regulation of transcription from RNA polymerase II promoter involved in defence response to Gram-negative bacterium|up regulation of global transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacteria|stimulation of global transcription from RNA polymerase II promoter involved in defence response to Gram-negative bacteria|activation of global transcription from RNA polymerase II promoter involved in defence response to Gram-negative bacterium|activation of transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacterium|up regulation of transcription from RNA polymerase II promoter involved in defence response to Gram-negative bacteria|up regulation of global transcription from RNA polymerase II promoter involved in defence response to Gram-negative bacterium|positive regulation of gene-specific transcription from RNA polymerase II promoter involved in defence response to Gram-negative bacterium|stimulation of global transcription from RNA polymerase II promoter involved in Gram-negative antibacterial peptide activity|upregulation of transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacterium|positive regulation of global transcription from Pol II promoter involved in defence response to Gram-negative bacteria|stimulation of transcription from RNA polymerase II promoter involved in defence response to Gram-negative bacterium|up-regulation of global transcription from RNA polymerase II promoter involved in defence response to Gram-negative bacteria|positive regulation of transcription from RNA polymerase II promoter involved in defence response to Gram-negative bacterium|upregulation of transcription from RNA polymerase II promoter involved in defence response to Gram-negative bacterium|stimulation of global transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacterium|upregulation of global transcription from RNA polymerase II promoter involved in defence response to Gram-negative bacterium|stimulation of transcription from RNA polymerase II promoter involved in defence response to Gram-negative bacteria|up-regulation of transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacteria|up regulation of transcription from RNA polymerase II promoter involved in Gram-negative antibacterial peptide activity|up regulation of transcription from RNA polymerase II promoter involved in defence response to Gram-negative bacterium|positive regulation of transcription from Pol II promoter involved in Gram-negative antibacterial peptide activity|stimulation of transcription from RNA polymerase II promoter involved in Gram-negative antibacterial peptide activity|up regulation of global transcription from RNA polymerase II promoter involved in Gram-negative antibacterial peptide activity|activation of transcription from RNA polymerase II promoter involved in defence response to Gram-negative bacterium|up regulation of transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacteria|up regulation of global transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacterium|positive regulation of transcription from Pol II promoter involved in defense response to Gram-negative bacterium|upregulation of transcription from RNA polymerase II promoter involved in Gram-negative antibacterial peptide activity|up-regulation of global transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacterium|upregulation of transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacteria|stimulation of global transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacteria|activation of global transcription from RNA polymerase II promoter involved in Gram-negative antibacterial peptide activity|positive regulation of transcription from Pol II promoter involved in defence response to Gram-negative bacterium|up-regulation of transcription from RNA polymerase II promoter involved in defence response to Gram-negative bacteria|positive regulation of global transcription from Pol II promoter involved in Gram-negative antibacterial peptide activity|positive regulation of transcription from Pol II promoter involved in defense response to Gram-negative bacteria|up-regulation of global transcription from RNA polymerase II promoter involved in Gram-negative antibacterial peptide activity|positive regulation of global transcription from Pol II promoter involved in defense response to Gram-negative bacteria|activation of transcription from RNA polymerase II promoter involved in Gram-negative antibacterial peptide activity|up regulation of transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacterium|activation of global transcription from RNA polymerase II promoter involved in defence response to Gram-negative bacteria|up regulation of global transcription from RNA polymerase II promoter involved in defence response to Gram-negative bacteria|positive regulation of transcription from Pol II promoter involved in defence response to Gram-negative bacteria|positive regulation of global transcription from Pol II promoter involved in defense response to Gram-negative bacterium|positive regulation of gene-specific transcription from RNA polymerase II promoter involved in Gram-negative antibacterial peptide activity							kmv	2013-04-30T16:54:30Z					biological_process											owl:Class	
GO:0034919	biolink:NamedThing	butyryl-CoA 2-C-propionyltransferase activity	Catalysis of the reaction: 2-methyl-3-oxohexanoyl-CoA + CoA = propanoyl-CoA + butyryl-CoA.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0931									molecular_function											owl:Class	
GO:0102638	biolink:NamedThing	[1-(2-amino-7-methyl-4-oxo-7,8-dihydro-3H-pteridin-6-yl)]ethyl-4-(beta-D-ribofuranosyl)aminobenzene 5'-phosphate synthase activity	Catalysis of the reaction: 4-(beta-D-ribofuranosyl)aminobenzene 5'-phosphate + [1-(2-amino-7-methyl-4-oxo-7,8-dihydro-3H-pteridin-6-yl)]ethyl diphosphate = [1-(2-amino-7-methyl-4-oxo-7,8-dihydro-3H-pteridin-6-yl)]ethyl-4-(beta-D-ribofuranosyl)aminobenzene 5'-phosphate + diphosphoric acid.	tmpzr1t_l9r_go_relaxed.owl					EC:2.5.1.105|MetaCyc:RXN-15734									molecular_function											owl:Class	
GO:0072548	biolink:NamedThing	dicoumaroyl monocaffeoyl spermidine meta-hydroxylase activity	Catalysis of the reaction: dicoumaroyl monocaffeoyl spermidine + NADPH + O2 = monocoumaroyl dicaffeoyl spermidine + NADP+ + H2O.	tmpzr1t_l9r_go_relaxed.owl								mah	2011-01-25T02:57:22Z					molecular_function											owl:Class	
GO:0043785	biolink:NamedThing	cinnamoyl-CoA:phenyllactate CoA-transferase activity	Catalysis of the reaction: (R)-3-phenyllactate + [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonatooxy)oxolan-2-yl]methyl {[(3R)-3-hydroxy-2,2-dimethyl-3-({2-[(2-{[(2E)-3-phenylprop-2-enoyl]sulfanyl}ethyl)carbamoyl]ethyl}carbamoyl)propyl phosphonato]oxy}phosphonate = (R)-3-phenyllactoyl-CoA + trans-cinnamate.	tmpzr1t_l9r_go_relaxed.owl	FldA|(E)-cinnamoyl-CoA:(R)-phenyllactate CoA-transferase activity				MetaCyc:2.8.3.17-RXN|KEGG_REACTION:R07796|RHEA:15601|EC:2.8.3.17									molecular_function											owl:Class	
GO:0060243	biolink:NamedThing	negative regulation of cell growth involved in contact inhibition	The negative regulation of cell growth in response to increased cell density.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0006191	biolink:NamedThing	deoxyinosine salvage	Any process that generates deoxyinosine from derivatives of it, without de novo synthesis.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0005458	biolink:NamedThing	GDP-mannose transmembrane transporter activity	Enables the transfer of a GDP-mannose from one side of a membrane to the other. GDP-mannose is a substance composed of mannose in glycosidic linkage with guanosine diphosphate.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0051373	biolink:NamedThing	FATZ binding	Binding to a member of the FATZ family of proteins, filamin-, actinin-, and telethonin-binding proteins of the Z-disc of striated muscle. FATZ proteins are located in the Z-disc of the sarcomere and are involved in a complex network of interactions with other Z-band components.	tmpzr1t_l9r_go_relaxed.owl	filamin-, actinin- and telethonin-binding protein of the Z-disc of striated muscle|FATZ 1 binding|calsarcin binding|FATZ 2 binding|FATZ 3 binding|calsarcin 3 binding|calsarcin 1 binding|calsarcin 2 binding											GO:0051376|GO:0051375|GO:0051374		molecular_function											owl:Class	
GO:1990932	biolink:NamedThing	5.8S rRNA binding	Binding to 5.8S ribosomal RNA, a eukaryotic ribosomal RNA which forms a complex with 28S RNA.	tmpzr1t_l9r_go_relaxed.owl								sl	2016-03-14T20:25:41Z					molecular_function											owl:Class	
GO:0042745	biolink:NamedThing	circadian sleep/wake cycle	The cycle from wakefulness through an orderly succession of sleep states and stages that occurs on an approximately 24 hour rhythm.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0042252	biolink:NamedThing	establishment of planar polarity of larval imaginal disc epithelium	Coordinated organization of groups of cells in the plane of a larval imaginal disc epithelium, such that they all orient to similar coordinates.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0021767	biolink:NamedThing	mammillary body development	The progression of the mammillary body over time from its initial formation until its mature state. The mammillary body is a protrusion at the posterior end of the hypothalamus that contains hypothalamic nuclei.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0004847	biolink:NamedThing	urea carboxylase activity	Catalysis of the reaction: ATP + bicarbonate + urea = ADP + 2 H(+) + phosphate + urea-1-carboxylate.	tmpzr1t_l9r_go_relaxed.owl	UCA activity|urea carboxylase (hydrolyzing) activity|urease (ATP-hydrolysing)|urea:carbon-dioxide ligase (ADP-forming)|urease (ATP-hydrolyzing) activity|ATP--urea amidolyase activity|urea amidolyase activity|UALase activity|urea carboxylase (hydrolysing)				KEGG_REACTION:R00774|EC:6.3.4.6|RHEA:20896|MetaCyc:UREA-CARBOXYLASE-RXN									molecular_function											owl:Class	
GO:0042293	biolink:NamedThing	Hub1 activating enzyme activity	Catalysis of the activation of the small ubiquitin-related modifier Hub1, through the formation of an ATP-dependent high-energy thiolester bond.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0090402	biolink:NamedThing	oncogene-induced cell senescence	A cellular senescence process associated with the dismantling of a cell as a response to oncogenic stress, such as the activation of the Ras oncogenic family.	tmpzr1t_l9r_go_relaxed.owl	OIS							tb	2011-01-05T02:37:57Z					biological_process											owl:Class	
GO:0140645	biolink:NamedThing	neutrophic extracellular trap formation	The aggregation, arrangement and bonding together of a set of components to form a neutrophil extracellular trap, a network of extracellular fibers primarily composed of DNA from neutrophils, which bind and neutralizes pathogens.	tmpzr1t_l9r_go_relaxed.owl	NET formation	https://github.com/geneontology/go-ontology/issues/21416			http://purl.obolibrary.org/obo/TXPO_0002149			pg	2021-05-12T07:08:07Z					biological_process											owl:Class	
GO:0047879	biolink:NamedThing	erythronolide synthase activity	Catalysis of the reaction: 6 malonyl-CoA + propionyl-CoA = 7 CoA + 6-deoxyerythronolide B.	tmpzr1t_l9r_go_relaxed.owl	erythronolide condensing enzyme activity|malonyl-CoA:propionyl-CoA malonyltransferase (cyclizing)				MetaCyc:ERYTHRONOLIDE-SYNTHASE-RXN|EC:2.3.1.94|RHEA:23068									molecular_function											owl:Class	
GO:0080095	biolink:NamedThing	phosphatidylethanolamine-sterol O-acyltransferase activity	Catalysis of the reaction: a phosphatidylethanolamine + a sterol = a sterol ester + a lysophosphatidylethanolamine.	tmpzr1t_l9r_go_relaxed.owl								dhl	2009-04-23T03:39:33Z					molecular_function											owl:Class	
GO:0002489	biolink:NamedThing	antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent	The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class Ib protein complex following intracellular transport via a TAP (transporter associated with antigen processing) pathway. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell and is dependent on TAP transport from the cytosol to ER for association with the MHC class Ib molecule. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E gene family.	tmpzr1t_l9r_go_relaxed.owl	endogenous peptide antigen processing and presentation via MHC class Ib via ER pathway, TAP-dependent|TAP-dependent antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway|TAP-dependent endogenous peptide antigen processing and presentation via MHC class Ib via ER pathway													biological_process											owl:Class	
GO:0000287	biolink:NamedThing	magnesium ion binding	Binding to a magnesium (Mg) ion.	tmpzr1t_l9r_go_relaxed.owl	Mg binding|magnesium binding													molecular_function											owl:Class	
GO:0045330	biolink:NamedThing	aspartyl esterase activity	Catalysis of the hydrolysis of an ester bond by a mechanism involving a catalytically active aspartic acid residue.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0090545	biolink:NamedThing	CHD-type complex	A SWI/SNF-type complex that contains a subunit from the CHD(Chromodomain helicase DNA-binding) family. The CHD family is characterized by two signature sequence motifs: tandem chromodomains located in the N-terminal region, and the SNF2-like ATPase domain located in the central region of the protein structure.	tmpzr1t_l9r_go_relaxed.owl								tb	2013-02-15T12:11:57Z					cellular_component											owl:Class	
GO:0005616	biolink:NamedThing	larval serum protein complex	A multisubunit protein complex which, in Drosophila, is a heterohexamer of three subunits, alpha, beta and gamma. The complex is thought to store amino acids for synthesis of adult proteins.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0055042	biolink:NamedThing	5-valerolactone hydrolase activity	Catalysis of the reaction: 5-valerolactone + H2O = 5-hydroxyvalerate.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0004744	biolink:NamedThing	retinal isomerase activity	Catalysis of the reaction: all-trans-retinal = 11-cis-retinal.	tmpzr1t_l9r_go_relaxed.owl	all-trans-retinal 11-cis-trans-isomerase activity|retinoid isomerase activity|retinene isomerase activity				MetaCyc:RETINAL-ISOMERASE-RXN|KEGG_REACTION:R02126|RHEA:24124									molecular_function											owl:Class	
GO:0001863	biolink:NamedThing	collectin receptor activity	Combining with a collectin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl						Note that collectins include such proteins as mannose-binding lectin (MBL) and surfactant proteins A and D (SP-A and SP-D).								molecular_function											owl:Class	
GO:0019123	biolink:NamedThing	peptidyl-methionine racemization	The racemization of peptidyl-methionine.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0193							GO:0018087|GO:0018369		biological_process											owl:Class	
GO:0052844	biolink:NamedThing	inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity	Catalysis of the reaction: inositol 3-diphosphate 1,2,4,5,6-pentakisphosphate + H2O = inositol 1,2,3,4,5,6-hexakisphosphate + phosphate + 2 H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-10978			ai	2011-12-05T10:59:26Z					molecular_function											owl:Class	
GO:0034074	biolink:NamedThing	marneral synthase activity	Catalysis of the reaction: oxidosqualene = marneral.	tmpzr1t_l9r_go_relaxed.owl					RHEA:31875|MetaCyc:RXN-9664									molecular_function											owl:Class	
GO:0031881	biolink:NamedThing	type 4 somatostatin receptor binding	Binding to a type 4 somatostatin receptor.	tmpzr1t_l9r_go_relaxed.owl	type 4 somatostatin receptor ligand													molecular_function											owl:Class	
GO:0071377	biolink:NamedThing	cellular response to glucagon stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucagon stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-12-11T03:25:07Z					biological_process											owl:Class	
GO:0047722	biolink:NamedThing	indolelactate dehydrogenase (NADH) activity	Catalysis of the reaction: 3-(indol-3-yl)lactate + NAD(+) = 3-(indol-3-yl)pyruvate + H(+) + NADH.	tmpzr1t_l9r_go_relaxed.owl	indolelactate:NAD+ oxidoreductase activity|(indol-3-yl)lactate:NAD+ oxidoreductase activity|indole-3-lactate dehydrogenase activity				KEGG_REACTION:R01971|EC:1.1.1.110|MetaCyc:INDOLELACTATE-DEHYDROGENASE-RXN|RHEA:20133									molecular_function											owl:Class	
GO:0032477	biolink:NamedThing	homodimeric decaprenyl diphosphate synthase complex	A homodimeric complex that possesses di-trans,poly-cis-decaprenylcistransferase activity; involved in ubiquinone biosynthesis.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0051992	biolink:NamedThing	UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine:undecaprenyl-phosphate transferase activity	Catalysis of the reaction: UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine + di-trans,poly-cis-undecaprenyl phosphate = UMP + N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine-diphosphoundecaprenol.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:PHOSNACMURPENTATRANS-RXN|RHEA:28386|EC:2.7.8.13	Note that EC classifies 'UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine:undecaprenyl-phosphate transferase activity ; GO:0051992' and 'phospho-N-acetylmuramoyl-pentapeptide-transferase activity ; GO:0008963' under the same EC number, EC:2.7.8.13.		ai	2010-07-06T12:10:01Z					molecular_function											owl:Class	
GO:0102420	biolink:NamedThing	sn-1-glycerol-3-phosphate C16:0-DCA-CoA acyl transferase activity	Catalysis of the reaction: hexadecanedioyl-CoA + sn-glycerol 3-phosphate = coenzyme A + 1-C16:0-alpha,omega-dicarboxyl-2-lysophosphatidate.	tmpzr1t_l9r_go_relaxed.owl					EC:2.3.1.15|MetaCyc:RXN-13805									molecular_function											owl:Class	
GO:0102802	biolink:NamedThing	thebaine 6-O-demethylase activity	Catalysis of the reaction: thebaine + 2-oxoglutarate + O2 <=> neopinone + formaldehyde + succinate + carbon dioxide.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-8147|RHEA:27477|EC:1.14.11.31									molecular_function											owl:Class	
GO:0061971	biolink:NamedThing	replacement bone morphogenesis	The process in which bones are generated and organized as a result of the conversion of another structural tissue into bone.	tmpzr1t_l9r_go_relaxed.owl								dph	2018-02-12T18:10:59Z					biological_process											owl:Class	
GO:1905200	biolink:NamedThing	gibberellic acid transmembrane transport	The directed movement of gibberellic acid across a membrane.	tmpzr1t_l9r_go_relaxed.owl								lr	2016-05-12T18:20:04Z					biological_process											owl:Class	
GO:0034710	biolink:NamedThing	inhibin complex binding	Binding to an inhibin complex, a dimer of one inhibin-alpha subunit and one inhibin-beta subunit.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0050964	biolink:NamedThing	detection of electrical stimulus involved in electroception	The series of events that contribute to electroception in which an electrical stimulus is received and converted into a molecular signal.	tmpzr1t_l9r_go_relaxed.owl	sensory transduction of electrical stimulus during electroception|electroception, sensory detection of electrical stimulus|sensory detection of electrical stimulus during electroception|electroception, sensory transduction|detection of electrical stimulus during electroreception|electroception, detection of electrical stimulus|electroception, sensory transduction of electrical stimulus													biological_process											owl:Class	
GO:0120153	biolink:NamedThing	calcium-dependent carbohydrate binding	Binding to a carbohydrate in the presence of calcium.	tmpzr1t_l9r_go_relaxed.owl								krc	2018-04-27T16:42:21Z					molecular_function											owl:Class	
GO:0031731	biolink:NamedThing	CCR6 chemokine receptor binding	Binding to a CCR6 chemokine receptor.	tmpzr1t_l9r_go_relaxed.owl	LARC receptor binding|CCR6 chemokine receptor ligand													molecular_function											owl:Class	
GO:0102693	biolink:NamedThing	UDP-glucose:kinetin 7-N-glucosyltransferase activity	Catalysis of the reaction: UDP-alpha-D-glucose + kinetin <=> H+ + kinetin-7-N-glucoside + UDP.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-4731									molecular_function											owl:Class	
GO:0070579	biolink:NamedThing	methylcytosine dioxygenase activity	Catalysis of the reaction: methylcytosine + 2-oxoglutarate + O2 = 5-hydroxymethylcytosine + succinate + CO2.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-5220952|Reactome:R-HSA-5221014|Reactome:R-HSA-5220990			mah	2009-04-22T02:29:41Z					molecular_function											owl:Class	
GO:1904764	biolink:NamedThing	chaperone-mediated autophagy translocation complex disassembly	The disaggregation of a chaperone-mediated autophagy translocation complex into its constituent components.	tmpzr1t_l9r_go_relaxed.owl	chaperone-mediated autophagy receptor complex disassembly|CMA receptor complex disassembly|CMA translocation complex disassembly							pad	2015-10-26T16:34:36Z					biological_process											owl:Class	
GO:0046741	biolink:NamedThing	transport of virus in host, tissue to tissue	The transport of a virus between tissues in a multicellular organism.	tmpzr1t_l9r_go_relaxed.owl	viral spread within host, tissue to tissue|spread of virus in host, tissue to tissue|spread of virus within host, tissue to tissue|tissue to tissue spread of virus within host													biological_process											owl:Class	
GO:0102886	biolink:NamedThing	alpha-chamigrene synthase activity	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate <=> alpha-chamigrene + diphosphoric acid.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-8428									molecular_function											owl:Class	
GO:0080049	biolink:NamedThing	L-gulono-1,4-lactone dehydrogenase activity	Catalysis of the reaction: L-gulono-1,4-lactone + 2 ferricytochrome c = L-ascorbate + 2 ferrocytochrome c.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-1439									molecular_function											owl:Class	
GO:0036250	biolink:NamedThing	peroxisome transport along microtubule	The directed movement of a peroxisome along a microtubule, mediated by motor proteins.	tmpzr1t_l9r_go_relaxed.owl								bf	2012-05-31T03:09:09Z					biological_process											owl:Class	
GO:0052870	biolink:NamedThing	tocopherol omega-hydroxylase activity	Catalysis of the reaction: tocopherol + O2 + NADPH + H+ = 13'-hydroxy-tocopherol + NADP+ + H2O .	tmpzr1t_l9r_go_relaxed.owl	tocopherol 13-hydroxylase activity							ai	2012-01-30T03:06:27Z					molecular_function											owl:Class	
GO:0050956	biolink:NamedThing	electroception	The series of events required for an organism to receive an electrical stimulus, convert it to a molecular signal, and recognize and characterize the signal. Many fish possess an electroception sense; for example, the electric eel uses low voltage pulses of electricity for navigation and prey location.	tmpzr1t_l9r_go_relaxed.owl	electroception sense|electroceptive sense				Wikipedia:Electroreception									biological_process											owl:Class	
GO:0002170	biolink:NamedThing	high-affinity IgA receptor activity	Combining with high affinity with an immunoglobulin of an IgA isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	high affinity IgA receptor activity							hjd	2010-05-06T05:00:11Z					molecular_function											owl:Class	
GO:0061865	biolink:NamedThing	polarized secretion of basement membrane proteins in epithelium	The basement membrane constituent secretion in which there is a restriction or targeting of basement membrane proteins for controlled release on the basal side of polarized epithelium.	tmpzr1t_l9r_go_relaxed.owl								dph	2017-04-07T18:26:02Z					biological_process											owl:Class	
GO:0034335	biolink:NamedThing	DNA negative supercoiling activity	Catalytic introduction of negative supercoils into a DNA molecule or region thereof. In bacteria, negative supercoils are only introduced by DNA gyrase, a type II topoisomerase, but not all DNA gyrases are capable of introducing supercoils. In bacteria, the level of supercoiling varies widely between species and has been characterized properly in only a handful of organisms. The best characterized enzyme, from E.coli, is exceptionally proficient at supercoiling and this ability is not representative of all bacteria.	tmpzr1t_l9r_go_relaxed.owl	DNA gyrase activity|DNA-gyrase activity					Note that this term was reinstated from obsolete.								molecular_function											owl:Class	
GO:0102650	biolink:NamedThing	cyclo-acetoacetyl-L-tryptophan synthetase activity	Catalysis of the reaction: acetoacetyl-ACP + L-tryptophan  + ATP <=> cyclo-acetoacetyl-L-tryptophan + AMP + diphosphoric acid + 2 H+ + a holo-[acyl-carrier protein].	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-15811									molecular_function											owl:Class	
GO:0072633	biolink:NamedThing	interleukin-30 production	The appearance of interleukin-30 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	tmpzr1t_l9r_go_relaxed.owl	interleukin-30 secretion|IL-30 production|interleukin-30 complex production											GO:0072634		biological_process											owl:Class	
GO:0004561	biolink:NamedThing	alpha-N-acetylglucosaminidase activity	Catalysis of the hydrolysis of terminal non-reducing N-acetyl-D-glucosamine residues in N-acetyl-alpha-D-glucosaminides.	tmpzr1t_l9r_go_relaxed.owl	N-acetyl-alpha-glucosaminidase activity|alpha-acetylglucosaminidase activity|NAG activity|N-acetyl-alpha-D-glucosaminidase activity|alpha-N-acetyl-D-glucosaminide N-acetylglucosaminohydrolase activity|alpha-D-2-acetamido-2-deoxyglucosidase activity				Reactome:R-HSA-2090038|Reactome:R-HSA-9036052|MetaCyc:3.2.1.50-RXN|Reactome:R-HSA-1678742|EC:3.2.1.50|Reactome:R-HSA-2263496									molecular_function											owl:Class	
GO:0061591	biolink:NamedThing	calcium activated galactosylceramide scrambling	The movement of a population of galactosylceramide molecules from one leaflet of the plasma membrane bilayer to the opposite leaflet as a result of a calcium stimulus.	tmpzr1t_l9r_go_relaxed.owl								dph	2014-02-05T15:25:52Z					biological_process											owl:Class	
GO:0008446	biolink:NamedThing	GDP-mannose 4,6-dehydratase activity	Catalysis of the reaction: GDP-alpha-D-mannose = GDP-4-dehydro-6-deoxy-alpha-D-mannose + H(2)O.	tmpzr1t_l9r_go_relaxed.owl	guanosine diphosphomannose oxidoreductase activity|GDP-mannose 4,6-hydro-lyase (GDP-4-dehydro-6-deoxy-D-mannose-forming)|guanosine 5'-diphosphate-D-mannose oxidoreductase activity|GDPmannose 4,6-dehydratase activity|GDP-D-mannose 4,6-dehydratase activity|GDP-D-mannose dehydratase activity|Gmd|guanosine diphosphomannose 4,6-dehydratase activity|GDP-mannose 4,6-hydro-lyase activity				MetaCyc:GDPMANDEHYDRA-RXN|Reactome:R-HSA-6787632|EC:4.2.1.47|KEGG_REACTION:R00888|RHEA:23820									molecular_function											owl:Class	
GO:0009271	biolink:NamedThing	phage shock	A response by bacterial cells to a variety of stresses including filamentous phage infection, mislocalization of envelope proteins, extremes of temperature, osmolarity or ethanol concentration, and the presence of proton ionophores such as carbonylcyanide m-chlorophenylhydrazone (CCCP), that involves expression of the phage shock protein operon, and acts to protect the bacterial cells from damage.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0010499	biolink:NamedThing	proteasomal ubiquitin-independent protein catabolic process	The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds that is mediated by the proteasome but do not involve ubiquitin.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0046562	biolink:NamedThing	glucose oxidase activity	Catalysis of the reaction: beta-D-glucose + O2 = D-glucono-1,5-lactone + H2O2.	tmpzr1t_l9r_go_relaxed.owl	microcid|penatin|deoxin-1|glucose oxyhydrase activity|beta-D-glucose:oxygen 1-oxido-reductase activity|D-glucose oxidase activity|D-glucose-1-oxidase activity|beta-D-glucose oxidase activity|beta-D-glucose:quinone oxidoreductase activity|corylophyline|beta-D-glucose:oxygen 1-oxidoreductase activity|glucose aerodehydrogenase activity|GOD activity				RHEA:11428|EC:1.1.3.4|KEGG_REACTION:R01522|MetaCyc:GLUCOSE-OXIDASE-RXN									molecular_function											owl:Class	
GO:0018686	biolink:NamedThing	6-hydroxy pseudo-oxynicotine monooxygenase activity	Catalysis of the reaction: 2 6-hydroxypseudooxynicotine + O2 = 2 2,6-dihydroxypseudooxynicotine.	tmpzr1t_l9r_go_relaxed.owl					EC:1.14.18.-|UM-BBD_reactionID:r0480									molecular_function											owl:Class	
GO:0071198	biolink:NamedThing	Kv4.1-DPP6 channel complex	A voltage-gated potassium channel complex that contains the peptidase-related protein DPP6 associated with the channel via interaction with the Kv alpha subunit 4.1.	tmpzr1t_l9r_go_relaxed.owl	Kv4.1-DPPX channel complex				CORUM:600			mah	2009-11-23T05:14:37Z					cellular_component											owl:Class	
GO:0031866	biolink:NamedThing	EP3 subtype prostaglandin E2 receptor binding	Binding to an EP3 subtype prostaglandin E2 receptor.	tmpzr1t_l9r_go_relaxed.owl	EP3 subtype prostaglandin E2 receptor ligand|prostanoid EP3 receptor binding													molecular_function											owl:Class	
GO:0007157	biolink:NamedThing	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules	The attachment of an adhesion molecule in one cell to a nonidentical adhesion molecule in an adjacent cell.	tmpzr1t_l9r_go_relaxed.owl	agglutination													biological_process											owl:Class	
GO:0018707	biolink:NamedThing	1-phenanthrol methyltransferase activity	Catalysis of the reaction: 1-phenanthrol + X-CH3 = X + 1-methoxyphenanthrene.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0493									molecular_function											owl:Class	
GO:0030756	biolink:NamedThing	isoorientin 3'-O-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine(1+) + isoorientin = S-adenosyl-L-homocysteine + H(+) + isoscoparin.	tmpzr1t_l9r_go_relaxed.owl	isoorientin 3'-methyltransferase activity|S-adenosyl-L-methionine:isoorientin 3'-O-methyltransferase activity				MetaCyc:ISOORIENTIN-3-O-METHYLTRANSFERASE-RXN|EC:2.1.1.78|KEGG_REACTION:R03731|RHEA:24096									molecular_function											owl:Class	
GO:0009025	biolink:NamedThing	tagatose-bisphosphate aldolase activity	Catalysis of the reaction: D-tagatose 1,6-diphosphate = D-glyceraldehyde 3-phosphate + glycerone phosphate.	tmpzr1t_l9r_go_relaxed.owl	D-tagatose-1,6-bisphosphate D-glyceraldehyde 3-phosphate-lyase (glycerone-phosphate-forming)|tagatose-1,6-bisphosphate aldolase 1|tagatose 1,6-diphosphate aldolase activity|AgaZ|D-tagatose-1,6-bisphosphate triosephosphate lyase activity|AgaY|KbaY|D-tagatose-1,6-bisphosphate aldolase activity				EC:4.1.2.40|KEGG_REACTION:R01069|RHEA:22948|MetaCyc:TAGAALDOL-RXN									molecular_function											owl:Class	
GO:0030476	biolink:NamedThing	ascospore wall assembly	The aggregation, arrangement and bonding together of a set of components to form an ascospore wall. During sporulation in Ascomycota, each ascospore nucleus becomes surrounded by a specialized spore wall, formed by deposition of spore wall components in the lumenal space between the outer and inner leaflets of the prospore membrane. An example of this process is found in Saccharomyces cerevisiae.	tmpzr1t_l9r_go_relaxed.owl	spore wall assembly											GO:0007152		biological_process											owl:Class	
GO:0043617	biolink:NamedThing	cellular response to sucrose starvation	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of sucrose.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0009666	biolink:NamedThing	plastid outer membrane organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the outer membrane of a plastid.	tmpzr1t_l9r_go_relaxed.owl	plastid outer membrane organization and biogenesis|plastid outer membrane organisation													biological_process											owl:Class	
GO:0000032	biolink:NamedThing	cell wall mannoprotein biosynthetic process	The chemical reactions and pathways resulting in the formation of cell wall mannoproteins, any cell wall protein that contains covalently bound mannose residues.	tmpzr1t_l9r_go_relaxed.owl	cell wall mannoprotein formation|cell wall mannoprotein anabolism|cell wall mannoprotein synthesis|cell wall mannoprotein biosynthesis													biological_process											owl:Class	
GO:0050174	biolink:NamedThing	phenylalanine decarboxylase activity	Catalysis of the reaction: L-phenylalanine = phenylethylamine + CO2.	tmpzr1t_l9r_go_relaxed.owl	L-phenylalanine decarboxylase activity|aromatic L-amino acid decarboxylase activity|L-phenylalanine carboxy-lyase (phenylethylamine-forming)|L-phenylalanine carboxy-lyase activity				EC:4.1.1.53|MetaCyc:PHENYLALANINE-DECARBOXYLASE-RXN|RHEA:19717									molecular_function											owl:Class	
GO:0035478	biolink:NamedThing	chylomicron binding	Binding to a chylomicron, a large lipoprotein particle (diameter 75-1200 nm) composed of a central core of triglycerides and cholesterol surrounded by a protein-phospholipid coating. The proteins include one molecule of apolipoprotein B-48 and may include a variety of apolipoproteins, including APOAs, APOCs and APOE.	tmpzr1t_l9r_go_relaxed.owl								bf	2010-04-23T10:18:52Z					molecular_function											owl:Class	
GO:0022859	biolink:NamedThing	dephosphorylation-gated channel activity	Enables the transmembrane transfer of a solute by a channel that opens in response to dephosphorylation of one of its constituent parts.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0050614	biolink:NamedThing	delta24-sterol reductase activity	Catalysis of the reaction: NADP+ + 5-alpha-cholest-7-en-3-beta-ol = NADPH + H+ + 5-alpha-cholesta-7,24-dien-3-beta-ol.	tmpzr1t_l9r_go_relaxed.owl	D24-sterol reductase activity|lanosterol delta24-reductase activity|sterol:NADP+ delta24-oxidoreductase activity|lanosterol Delta(24)-reductase activity				Reactome:R-HSA-196417|MetaCyc:1.3.1.72-RXN|RHEA:13685|Reactome:R-HSA-6807064|EC:1.3.1.72									molecular_function											owl:Class	
GO:0036141	biolink:NamedThing	L-phenylalanine-oxaloacetate transaminase activity	Catalysis of the reaction L-phenylalanine + oxaloacetate = phenylpyruvate + aspartate.	tmpzr1t_l9r_go_relaxed.owl	L-phenylalanine:oxaloacetate transaminase activity							bf	2012-03-08T10:35:44Z					molecular_function											owl:Class	
GO:0030372	biolink:NamedThing	high molecular weight B cell growth factor receptor binding	Binding to a high molecular weight B cell growth factor receptor.	tmpzr1t_l9r_go_relaxed.owl	high molecular weight B cell growth factor receptor ligand|high molecular weight B-lymphocyte growth factor receptor binding|high molecular weight B-cell growth factor receptor binding|high molecular weight B lymphocyte growth factor receptor binding													molecular_function											owl:Class	
GO:0050219	biolink:NamedThing	prostaglandin-A1 delta-isomerase activity	Catalysis of the reaction: prostaglandin A1 = prostaglandin C1.	tmpzr1t_l9r_go_relaxed.owl	(13E)-(15S)-15-hydroxy-9-oxoprosta-10,13-dienoate delta10-delta11-isomerase activity|prostaglandin-A1 D-isomerase activity|prostaglandin A isomerase activity				KEGG_REACTION:R04565|MetaCyc:PROSTAGLANDIN-A1-DELTA-ISOMERASE-RXN|RHEA:10460|EC:5.3.3.9									molecular_function											owl:Class	
GO:0034302	biolink:NamedThing	akinete formation	The process in which an akinete, a thick-walled (encysted) dormant cell derived from the enlargement of a vegetative cell, is formed. Akinetes typically have granular cytoplasm, are more resistant to environmental extremes than vegetative cells, and are characteristic of several groups of Cyanobacteria.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0031957	biolink:NamedThing	very long-chain fatty acid-CoA ligase activity	Catalysis of the reaction: ATP + a very-long-chain fatty acid + CoA = AMP + diphosphate + an acyl-CoA; a very long-chain fatty acid is a fatty acid which has a chain length greater than C22.	tmpzr1t_l9r_go_relaxed.owl	very-long-chain fatty acid-CoA ligase activity|very-long-chain-fatty-acid-CoA ligase activity|very-long-chain fatty acid activation				Reactome:R-HSA-5695957|Reactome:R-HSA-5696007|Reactome:R-HSA-8875077									molecular_function											owl:Class	
GO:0050627	biolink:NamedThing	mycothione reductase activity	Catalysis of the reaction: NAD(P)+ + mycothiol = NAD(P)H + H+ + mycothione.	tmpzr1t_l9r_go_relaxed.owl	mycothiol:NAD(P)+ oxidoreductase activity|mycothiol-disulfide reductase activity				MetaCyc:1.8.1.15-RXN|EC:1.8.1.15									molecular_function											owl:Class	
GO:0097030	biolink:NamedThing	CENP-A containing nucleosome binding	Binding to a centromere-specific nucleosome, a form of nucleosome located only at the centromere, in which the histone H3 is replaced by the variant form CENP-A (sometimes known as CenH3).	tmpzr1t_l9r_go_relaxed.owl	centromeric nucleosome binding|centromere-specific nucleosome binding							pr	2011-04-01T03:19:35Z					molecular_function											owl:Class	
GO:0036218	biolink:NamedThing	dTTP diphosphatase activity	Catalysis of the reaction: dTTP + H2O = dTMP + diphosphate.	tmpzr1t_l9r_go_relaxed.owl					RHEA:28534|EC:3.6.1.9|MetaCyc:RXN0-5107			bf	2012-05-08T01:47:59Z					molecular_function											owl:Class	
GO:0102236	biolink:NamedThing	trans-4-hexen-3-one reductase activity	Catalysis of the reaction: trans-4-hexen-3-one + NADPH + H+ <=> hexan-3-one + NADP.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-12296									molecular_function											owl:Class	
GO:0061831	biolink:NamedThing	apical ectoplasmic specialization	Testis-specific junction between mature spermatids and Sertoli cells at the luminal end of the Sertoli cell.	tmpzr1t_l9r_go_relaxed.owl	apical ES													cellular_component											owl:Class	
GO:1901358	biolink:NamedThing	beta-D-galactofuranose biosynthetic process	The chemical reactions and pathways resulting in the formation of beta-D-galactofuranose.	tmpzr1t_l9r_go_relaxed.owl	beta-D-galactofuranose biosynthesis|beta-D-galactofuranose synthesis|beta-D-galactofuranose anabolism|beta-D-galactofuranose formation							di	2012-09-13T22:19:47Z					biological_process											owl:Class	
GO:0004100	biolink:NamedThing	chitin synthase activity	Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + [->4)-N-acetyl-beta-D-glucosaminyl-(1-](n) = UDP + [->4)-N-acetyl-beta-D-glucosaminyl-(1-](n+1).	tmpzr1t_l9r_go_relaxed.owl	chitin-uridine diphosphate acetylglucosaminyltransferase activity|UDP-N-acetyl-D-glucosamine:chitin 4-beta-N-acetylglucosaminyl-transferase activity|chitin synthetase activity|chitin-UDP acetyl-glucosaminyl transferase activity|trans-N-acetylglucosaminosylase activity|chitin-UDP N-acetylglucosaminyltransferase activity				RHEA:16637|MetaCyc:CHITIN-SYNTHASE-RXN|EC:2.4.1.16									molecular_function											owl:Class	
GO:0019440	biolink:NamedThing	tryptophan catabolic process to indole-3-acetate	The chemical reactions and pathways resulting in the breakdown of tryptophan into other compounds, including indole-3-acetate.	tmpzr1t_l9r_go_relaxed.owl	tryptophan catabolic process to IAA|tryptophan degradation to indole-3-acetate|tryptophan catabolic process to indoleacetic acid|tryptophan catabolism to indoleacetic acid|tryptophan breakdown to indole-3-acetate				MetaCyc:TRPIAACAT-PWY									biological_process											owl:Class	
GO:0102993	biolink:NamedThing	linolenate delta15 desaturase activity	Catalysis of the reaction: O2 + a lipid linoleoyl group + a reduced electron acceptor <=> 2 H2O + a lipid alpha-linolenoyl group + an oxidized electron acceptor.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-9667|RHEA:46408									molecular_function											owl:Class	
GO:0061484	biolink:NamedThing	hematopoietic stem cell homeostasis	Any biological process involved in the maintenance of the steady-state number of hematopoietic stem cells within a population of cells.	tmpzr1t_l9r_go_relaxed.owl								dph	2012-12-04T09:41:02Z					biological_process											owl:Class	
GO:0047476	biolink:NamedThing	3-alpha,7-alpha-dihydroxy-5-beta-cholestanate-CoA ligase activity	Catalysis of the reaction: CoA + 3-alpha,7-alpha-dihydroxy-5-beta-cholestanate + ATP = 3-alpha,7-alpha-dihydroxy-5-beta-cholestanoyl-CoA + diphosphate + AMP.	tmpzr1t_l9r_go_relaxed.owl	3alpha,7alpha-dihydroxy-5beta-cholestanate-CoA ligase activity|3alpha,7alpha-dihydroxy-5beta-cholestanate:CoA ligase (AMP-forming)|3alpha,7alpha-dihydroxy-5beta-cholestanoyl coenzyme A synthetase activity|DHCA-CoA ligase activity				EC:6.2.1.28|MetaCyc:6.2.1.28-RXN|RHEA:21776									molecular_function											owl:Class	
GO:0102387	biolink:NamedThing	2-phenylethanol acetyltransferase activity	Catalysis of the reaction: 2-phenylethanol + acetyl-CoA = phenethyl acetate + coenzyme A.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-13542|EC:2.3.1.224									molecular_function											owl:Class	
GO:0061967	biolink:NamedThing	establishment of left sidedness	The initial formation of the type asymmetry in an organism's body plan or part of an organism that established the pattern characteristic to its left side.	tmpzr1t_l9r_go_relaxed.owl								dph	2018-02-12T16:32:41Z					biological_process											owl:Class	
GO:0002153	biolink:NamedThing	steroid receptor RNA activator RNA binding	Binding to a steroid receptor RNA activator RNA (SRA). SRA enhances steroid hormone receptor transcriptional activity as an RNA transcript by an indirect mechanism that does not involve SRA-steroid receptor binding.	tmpzr1t_l9r_go_relaxed.owl	SRA binding					Note: there is also evidence that the RNA itself may code a protein (solution structure of mouse steroid receptor RNA activator 1 (SRA1) protein submitted to PDB by Riken).		hjd	2009-11-16T02:18:55Z					molecular_function											owl:Class	
GO:0070847	biolink:NamedThing	core mediator complex	A protein complex that interacts with the carboxy-terminal domain of the largest subunit of RNA polymerase II and plays an active role in transducing the signal from a transcription factor to the transcriptional machinery. The core mediator complex has a stimulatory effect on basal transcription, and contains most of the same subdomains as the larger form of mediator complex -- a head domain comprising proteins known in Saccharomyces as Srb2, -4, and -5, Med6, -8, and -11, and Rox3 proteins; a middle domain comprising Med1, -4, and -7, Nut1 and -2, Cse2, Rgr1, Soh1, and Srb7 proteins; and a tail consisting of Gal11p, Med2p, Pgd1p, and Sin4p -- but lacks the regulatory subcomplex comprising Ssn2, -3, and -8, and Srb8 proteins. Metazoan core mediator complexes have similar modular structures and include homologs of yeast Srb and Med proteins.	tmpzr1t_l9r_go_relaxed.owl	C mediator complex|S mediator complex	https://github.com/geneontology/go-ontology/issues/15979						mah	2009-08-04T02:56:11Z					cellular_component											owl:Class	
GO:0016490	biolink:NamedThing	structural constituent of peritrophic membrane	The action of a molecule that contributes to the structural integrity of the peritrophic membrane, a tubular sheath of cuticle that shields the epithelial cells of the midgut from the gut contents. An example of this is found in Drosophila melanogaster.	tmpzr1t_l9r_go_relaxed.owl	structural constituent of peritrophic matrix													molecular_function											owl:Class	
GO:0062070	biolink:NamedThing	SAGA complex binding	Binding to a SAGA complex.	tmpzr1t_l9r_go_relaxed.owl								dph	2018-08-31T14:13:36Z					molecular_function											owl:Class	
GO:0051979	biolink:NamedThing	alginic acid acetylation	The addition of O-acetyl ester groups to alginic acid, a linear polymer of D-mannuronate and L-guluronate.	tmpzr1t_l9r_go_relaxed.owl	alginate acetylation													biological_process											owl:Class	
GO:0102441	biolink:NamedThing	syringetin 7-O-methyltransferase activity	Catalysis of the reaction: syringetin(1-) + S-adenosyl-L-methionine  <=> 7,3',5'-trimethylmyricetin + S-adenosyl-L-homocysteine.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-13919									molecular_function											owl:Class	
GO:0032949	biolink:NamedThing	regulation of alpha-glucan biosynthetic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways relusting in the formation of alpha-glucans.	tmpzr1t_l9r_go_relaxed.owl	regulation of alpha-glucan anabolism|regulation of alpha-glucan synthesis|regulation of alpha-glucan biosynthesis|regulation of alpha-glucan formation													biological_process											owl:Class	
GO:0004745	biolink:NamedThing	NAD-retinol dehydrogenase activity	Catalysis of the reaction: retinol + NAD+ = retinal + NADH + H+.	tmpzr1t_l9r_go_relaxed.owl	retinene reductase activity|retinol (vitamin A1) dehydrogenase activity|retinal reductase activity|all-trans retinol dehydrogenase activity|retinol dehydrogenase activity	https://github.com/geneontology/go-ontology/issues/20980			Reactome:R-HSA-2466832|Reactome:R-HSA-5362564|MetaCyc:RETINOL-DEHYDROGENASE-RXN|RHEA:21284|Reactome:R-HSA-5362721|Reactome:R-HSA-5362518|Reactome:R-HSA-2454081|EC:1.1.1.105									molecular_function											owl:Class	
GO:0031039	biolink:NamedThing	macronucleus	A membrane-bounded organelle of ciliated protozoan cells that contains polyploid copies of a portion of the cell's complete genome. Transcription of genes occurs in macronuclei. Some ciliate species may contain multiple macronuclei per cell.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Macronucleus									cellular_component											owl:Class	
GO:0033428	biolink:NamedThing	CAG codon-amino acid adaptor activity	A triplet codon-amino acid adaptor activity that recognizes a CAG codon.	tmpzr1t_l9r_go_relaxed.owl	glutamine tRNA					Note that in the standard genetic code, CAG codes for glutamine.								molecular_function											owl:Class	
GO:0051669	biolink:NamedThing	fructan beta-fructosidase activity	Catalysis of the hydrolysis of terminal, non-reducing 2,1- and 2,6-linked beta-D-fructofuranose residues in fructans.	tmpzr1t_l9r_go_relaxed.owl	fructan b-fructosidase activity|polysaccharide beta-fructofuranosidase activity|fructan exohydrolase activity|exo-beta-fructosidase activity|exo-beta-D-fructosidase activity|fructanase activity|beta-D-fructan fructohydrolase activity				EC:3.2.1.80|MetaCyc:3.2.1.80-RXN									molecular_function											owl:Class	
GO:0071111	biolink:NamedThing	cyclic-guanylate-specific phosphodiesterase activity	Catalysis of the reaction: cyclic di-3',5'-guanylate + H(2)O = 5'-phosphoguanylyl(3'->5')guanosine + H(+).	tmpzr1t_l9r_go_relaxed.owl	c-di-GMP phosphodiesterase activity|VieA|phosphodiesterase A1 activity|c-di-GMP-specific phosphodiesterase activity|cyclic bis(3->5')diguanylate phosphodiesterase activity|PDEA1				MetaCyc:RXN0-4181|KEGG_REACTION:R08991|EC:3.1.4.52|RHEA:24902			mah	2009-11-13T02:10:39Z					molecular_function											owl:Class	
GO:0019086	biolink:NamedThing	late viral transcription	The transcription of the final group of viral genes of the viral life cycle, following middle transcription, or where middle transcription doesn't occur, following early transcription. Involves the transcription of genes encoding structural proteins.	tmpzr1t_l9r_go_relaxed.owl	late viral mRNA transcription													biological_process											owl:Class	
GO:0002944	biolink:NamedThing	cyclin K-CDK12 complex	A protein complex consisting of cyclin Kand cyclin-dependent kinase 12 (CDK12). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner.	tmpzr1t_l9r_go_relaxed.owl	CycK/Cdk12 complex							hjd	2012-12-05T16:09:48Z					cellular_component											owl:Class	
GO:0043778	biolink:NamedThing	cobalt-precorrin-8 methylmutase activity	Catalysis of the reaction: cobalt-precorrin 8 = cobyrinate.	tmpzr1t_l9r_go_relaxed.owl	cobalt-precorrin 8X methylmutase activity|cobalt-precorrin-8X methylmutase activity|cobalt-precorrin 8 methylmutase activity				MetaCyc:RXN-8768|EC:5.4.99.60|RHEA:16209									molecular_function											owl:Class	
GO:0042004	biolink:NamedThing	feminization of hermaphrodite soma	Promotion of female sex and sexual phenotypes in the hermaphroditic soma. An example of this is found in Caenorhabditis elegans.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1990468	biolink:NamedThing	NuA3b histone acetyltransferase complex	A NuA3 complex that catalyzes the acetylation of Histone H3. In S. cerevisiae, this complex consists of Eaf6p, Nto1p, Sas3p, Taf14p, Pdp3 and associates with H3K4me3 via Pdp3p.	tmpzr1t_l9r_go_relaxed.owl								rb	2014-08-25T23:13:37Z					cellular_component											owl:Class	
GO:0045348	biolink:NamedThing	positive regulation of MHC class II biosynthetic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of MHC class II.	tmpzr1t_l9r_go_relaxed.owl	up regulation of MHC class II biosynthetic process|positive regulation of MHC class II synthesis|positive regulation of MHC class II biosynthesis|positive regulation of major histocompatibility complex class II biosynthesis|stimulation of MHC class II biosynthetic process|activation of MHC class II biosynthetic process|positive regulation of major histocompatibility complex class II biosynthetic process|up-regulation of MHC class II biosynthetic process|positive regulation of MHC class II formation|positive regulation of MHC class II anabolism|upregulation of MHC class II biosynthetic process													biological_process											owl:Class	
GO:0090570	biolink:NamedThing	RNA polymerase I transcription repressor complex	A protein complex, located in the nucleus, that possesses activity that prevents or downregulates transcription from a RNA polymerase I promoter.	tmpzr1t_l9r_go_relaxed.owl								tb	2014-05-09T13:26:16Z					cellular_component											owl:Class	
GO:1990403	biolink:NamedThing	embryonic brain development	The process occurring during the embryonic phase whose specific outcome is the progression of the brain over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl								sl	2014-06-23T20:57:13Z					biological_process											owl:Class	
GO:0004364	biolink:NamedThing	glutathione transferase activity	Catalysis of the reaction: R-X + glutathione = H-X + R-S-glutathione. R may be an aliphatic, aromatic or heterocyclic group; X may be a sulfate, nitrile or halide group.	tmpzr1t_l9r_go_relaxed.owl	glutathione S-transferase activity|glutathione S-aryltransferase activity|RX:glutathione R-transferase activity|glutathione S-aralkyltransferase activity|glutathione S-alkyltransferase activity|S-(hydroxyalkyl)glutathione lyase activity|glutathione S-alkyl transferase activity|glutathione conjugation reaction				Reactome:R-HSA-9026780|Reactome:R-HSA-9026911|Reactome:R-HSA-176059|EC:2.5.1.18|Reactome:R-HSA-3301943|Reactome:R-HSA-9026901|Reactome:R-HSA-5423653|MetaCyc:GSHTRAN-RXN|Reactome:R-HSA-9026777|Reactome:R-HSA-176054									molecular_function											owl:Class	
GO:0050649	biolink:NamedThing	testosterone 6-beta-hydroxylase activity	Catalysis of the reaction: testosterone + donor-H2 + O2 = 6-beta-hydroxytestosterone + H2O.	tmpzr1t_l9r_go_relaxed.owl	testosterone 6b-hydroxylase activity													molecular_function											owl:Class	
GO:0043014	biolink:NamedThing	alpha-tubulin binding	Binding to the microtubule constituent protein alpha-tubulin.	tmpzr1t_l9r_go_relaxed.owl	alpha tubulin binding													molecular_function											owl:Class	
GO:0010428	biolink:NamedThing	methyl-CpNpG binding	Binding to a methylated cytosine/unspecified/guanine trinucleotide.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0031710	biolink:NamedThing	neuromedin B receptor binding	Binding to a neuromedin B receptor.	tmpzr1t_l9r_go_relaxed.owl	neuromedin B receptor ligand													molecular_function											owl:Class	
GO:0010378	biolink:NamedThing	temperature compensation of the circadian clock	The process in which the circadian clock maintains robust and accurate timing over a broad range of physiological temperatures. The circadian clock is an endogenous 24-h timer found in most eukaryotes and in photosynthetic bacteria. The clock drives rhythms in the physiology, biochemistry, and metabolism of the organisms.	tmpzr1t_l9r_go_relaxed.owl	regulation of the circadian clock by temperature													biological_process											owl:Class	
GO:1900872	biolink:NamedThing	pentadec-1-ene metabolic process	The chemical reactions and pathways involving pentadec-1-ene.	tmpzr1t_l9r_go_relaxed.owl	pentadec-1-ene metabolism							tt	2012-06-13T01:45:22Z					biological_process											owl:Class	
GO:0018697	biolink:NamedThing	carbonyl sulfide nitrogenase activity	Catalysis of the reaction: carbonyl sulfide + 2 H+ + 2 e- = hydrogen sulfide + carbon monoxide.	tmpzr1t_l9r_go_relaxed.owl	carbonyl sulphide nitrogenase activity				EC:1.18.6.1|UM-BBD_reactionID:r0600									molecular_function											owl:Class	
GO:0047998	biolink:NamedThing	hyoscyamine (6S)-dioxygenase activity	Catalysis of the reaction: 2-oxoglutarate + L-hyoscyamine + O(2) = (6S)-6-hydroxyhyoscyamine + CO(2) + succinate.	tmpzr1t_l9r_go_relaxed.owl	L-hyoscyamine,2-oxoglutarate:oxygen oxidoreductase ((6S)-hydroxylating)|hyoscyamine (6S)-hydroxylase activity|hyoscyamine 6beta-dioxygenase activity|hyoscyamine 6beta-hydroxylase activity|hyoscyamine 6-hydroxylase activity|hyoscyamine 6-beta-hydroxylase activity				RHEA:12629|MetaCyc:HYOSCYAMINE-6-DIOXYGENASE-RXN|EC:1.14.11.11|KEGG_REACTION:R03812									molecular_function											owl:Class	
GO:0044485	biolink:NamedThing	envenomation resulting in fibrinogenolysis in other organism	The process which begins with venom being forced into an organism by the bite or sting of another organism, and ends with fibrinogenolysis, a process that degrades fibrinogen at a variety of Arg-Lys bonds, thus impairing fibrinogen clotting in the bloodstream of the bitten/stung organism.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-01-26T03:41:01Z					biological_process											owl:Class	
GO:0044536	biolink:NamedThing	envenomation resulting in depletion of circulating fibrinogen in other organism	The process which begins with venom being forced into an organism by the bite or sting of another organism, and ends with a reduction in the quantity of fibrinogen found in the bloodstream of the bitten/stung organism.	tmpzr1t_l9r_go_relaxed.owl	envenomation resulting in negative regulation of circulating fibrinogen in other organism							jl	2012-03-21T02:56:49Z					biological_process											owl:Class	
GO:0015655	biolink:NamedThing	alanine:sodium symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: alanine(out) + Na+(out) = alanine(in) + Na+(in).	tmpzr1t_l9r_go_relaxed.owl	sodium:alanine symporter activity				RHEA:29283			jl	2012-08-08T12:57:30Z			GO:0044670		molecular_function											owl:Class	
GO:1990357	biolink:NamedThing	terminal web	An actin-rich cytoskeletal network located beneath the microvilli of the apical plasma membrane of polarized epithelial cells. In addition to actin filaments, the terminal web may contain actin-binding proteins, myosin motor proteins, and intermediate filaments. The terminal web can function as a contractile structure that influences the spatial distribution of microvilli as well as the development and morphogenesis of tissues containing polarized epithelial cells.	tmpzr1t_l9r_go_relaxed.owl								pr	2014-04-03T14:29:59Z					cellular_component											owl:Class	
GO:0051508	biolink:NamedThing	stigmasterol UDP-glucosyltransferase activity	Catalysis of the reaction: UDP-glucose + stigmasterol = UDP + O-glucosyl-stigmasterol.	tmpzr1t_l9r_go_relaxed.owl					RHEA:61828|MetaCyc:RXN-12126									molecular_function											owl:Class	
GO:0033678	biolink:NamedThing	5'-3' DNA/RNA helicase activity	Unwinding of a DNA/RNA duplex in the 5' to 3' direction, driven by ATP hydrolysis.	tmpzr1t_l9r_go_relaxed.owl	5' to 3' DNA/RNA helicase activity|ATP-dependent 5' to 3' DNA/RNA helicase activity|ATP-dependent 5'-3' DNA/RNA helicase activity	https://github.com/geneontology/go-ontology/issues/21612			Reactome:R-HSA-163120							GO:0033682		molecular_function											owl:Class	
GO:0060449	biolink:NamedThing	bud elongation involved in lung branching	The process in which a bud in the lung grows out from the point where it is formed.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1990502	biolink:NamedThing	dense core granule maturation	Steps required to transform a dense core granule generated at the trans-Golgi network into a fully formed and transmissible dense core granule. Dense core granule maturation proceeds through clathrin-mediated membrane remodeling events and is essential for efficient processing of cargo within dense core granules as well as for removing factors that might otherwise interfere with dense core granule trafficking and exocytosis.	tmpzr1t_l9r_go_relaxed.owl	dense core vesicle maturation							kmv	2014-09-30T20:35:11Z					biological_process											owl:Class	
GO:0047643	biolink:NamedThing	alginate synthase activity	Catalysis of the reaction: GDP-D-mannuronate + alginate(n) = GDP + alginate(n+1).	tmpzr1t_l9r_go_relaxed.owl	GDP-D-mannuronate:alginate D-mannuronyltransferase activity|mannuronosyl transferase activity				MetaCyc:ALGINATE-SYNTHASE-RXN|RHEA:46876|EC:2.4.1.33									molecular_function											owl:Class	
GO:0043866	biolink:NamedThing	adenylyl-sulfate reductase (thioredoxin) activity	Catalysis of the reaction: AMP + sulfite + thioredoxin disulfide = 5'-adenylyl sulfate + thioredoxin.	tmpzr1t_l9r_go_relaxed.owl	thioredoxin-dependent 5'-adenylylsulfate reductase activity|AMP, sulfite:thioredoxin-disulfide oxidoreductase (adenosine-5'-phosphosulfate-forming)|AMP,sulfite:thioredoxin-disulfide oxidoreductase (adenosine-5'-phosphosulfate-forming)				RHEA:21976|EC:1.8.4.10									molecular_function											owl:Class	
GO:0051214	biolink:NamedThing	RNAi-mediated antiviral immunity against RNA virus	Gene silencing induced by RNA viruses leading to a sequence-specific degradation of target mRNAs or post-transcriptional gene silencing. In plants, DCL4 is the primary Dicer to detect RNA viruses.	tmpzr1t_l9r_go_relaxed.owl	RNA virus induced gene silencing|RNA virus-induced gene silencing|RNA VIGS	https://github.com/geneontology/go-ontology/issues/19958												biological_process											owl:Class	
GO:0036205	biolink:NamedThing	histone catabolic process	The chemical reactions and pathways resulting in the breakdown of a histone protein by individual cells.	tmpzr1t_l9r_go_relaxed.owl	histone protein catabolic process					This term was created even though it describes a process relating to a group of gene products, because histones are highly conserved proteins that are essential components of cellular chromatin in eukaryotic cells.		bf	2012-04-24T04:48:48Z					biological_process											owl:Class	
GO:0043826	biolink:NamedThing	sulfur oxygenase reductase activity	Catalysis of the reaction: 5 sulfur + oxygen + 4 H2O = sulfite + thiosulfate + 2 hydrogen sulfide + 9 H+.	tmpzr1t_l9r_go_relaxed.owl	sulphur oxygenase reductase activity|SOR				MetaCyc:RXN-8226									molecular_function											owl:Class	
GO:0036134	biolink:NamedThing	12-hydroxyheptadecatrienoic acid synthase activity	Catalysis of the reaction: prostaglandin H2 = 12-hydroxyheptadecatrienoic acid (HHT) + malonaldehyde (MDA).	tmpzr1t_l9r_go_relaxed.owl	prostaglandin H2 degradation activity				RHEA:48644|Reactome:R-HSA-2161613			bf	2012-03-05T11:17:34Z					molecular_function											owl:Class	
GO:0030342	biolink:NamedThing	1-alpha,25-dihydroxyvitamin D3 24-hydroxylase activity	Catalysis of the hydroxylation of C-24 of 1-alpha,25-hydroxycholecalciferol (25-hydroxyvitamin D3; calcitriol).	tmpzr1t_l9r_go_relaxed.owl	calcitriol 24-hydroxylase activity|1,25-(OH)2D3 24-hydroxylase activity				Reactome:R-HSA-5602004|Reactome:R-HSA-211950|Reactome:R-HSA-209765									molecular_function											owl:Class	
GO:0004569	biolink:NamedThing	glycoprotein endo-alpha-1,2-mannosidase activity	Catalysis of the hydrolysis of the terminal alpha-glucosyl-(1,3)-mannosyl unit from Glc-Man(9)-(GlcNAc)(2) oligosaccharide component of the glycoprotein produced in the Golgi membrane.	tmpzr1t_l9r_go_relaxed.owl	glycoprotein glucosylmannohydrolase activity|glucosyl mannosidase activity|glucosylmannosidase activity|endomannosidase activity|endo-alpha-mannosidase activity				Reactome:R-HSA-964759|MetaCyc:3.2.1.130-RXN|EC:3.2.1.130|RHEA:54824									molecular_function											owl:Class	
GO:0036048	biolink:NamedThing	protein desuccinylation	The removal of a succinyl group (CO-CH2-CH2-CO) from a residue in a peptide or protein.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-12-12T09:42:35Z					biological_process											owl:Class	
GO:0033656	biolink:NamedThing	modification by symbiont of host chloroplast	The process in which an organism effects a change in the structure or function of host cell chloroplasts. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0047439	biolink:NamedThing	3-deoxy-D-manno-octulosonate aldolase activity	Catalysis of the reaction: 3-deoxy-D-manno-octulosonate = D-arabinose + pyruvate.	tmpzr1t_l9r_go_relaxed.owl	KDOaldolase activity|2-keto-3-deoxyoctonate aldolase activity|3-deoxy-D-manno-octulosonate D-arabinose-lyase activity|3-deoxy-D-manno-octulosonic aldolase activity|3-deoxy-D-manno-octulosonate D-arabinose-lyase (pyruvate-forming)|2-keto-3-deoxyoctonic aldolase activity|3-deoxyoctulosonic aldolase activity				EC:4.1.2.23|MetaCyc:4.1.2.23-RXN|KEGG_REACTION:R01576|RHEA:23340									molecular_function											owl:Class	
GO:0033852	biolink:NamedThing	thyroid-hormone transaminase activity	Catalysis of the reaction: 2-oxoglutarate + 3,5,3'-triiodo-L-thyronine = 3,5,3'-triiodothyropyruvate + L-glutamate.	tmpzr1t_l9r_go_relaxed.owl	thyroid-hormone aminotransferase activity|3,5-dinitrotyrosine aminotransferase activity|thyroid hormone aminotransferase activity|3,5-dinitrotyrosine transaminase activity|L-3,5,3'-triiodothyronine:2-oxoglutarate aminotransferase activity				RHEA:19133|MetaCyc:THYROID-HORMONE-AMINOTRANSFERASE-RXN|KEGG_REACTION:R03952|EC:2.6.1.26									molecular_function											owl:Class	
GO:0022875	biolink:NamedThing	protein-N(PI)-phosphohistidine-galactitol phosphotransferase system transmembrane transporter activity	Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + galactitol(out) = protein histidine + galactitol phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.	tmpzr1t_l9r_go_relaxed.owl	galactitol PTS transporter activity													molecular_function											owl:Class	
GO:0102925	biolink:NamedThing	solanine UDP-galactose galactosyltransferase activity	Catalysis of the reaction: UDP-D-galactose + solanidine = H+ + gamma-solanine + UDP.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-8875									molecular_function											owl:Class	
GO:0031473	biolink:NamedThing	myosin III binding	Binding to a class III myosin; myosin III is monomeric and has an N terminal kinase domain.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1902601	biolink:NamedThing	silver ion transmembrane transport	The directed movement of silver ion across a membrane.	tmpzr1t_l9r_go_relaxed.owl	silver transmembrane transport							pr	2013-12-20T11:08:46Z					biological_process											owl:Class	
GO:0043714	biolink:NamedThing	(R)-citramalate synthase activity	Catalysis of the reaction: pyruvate + acetyl-CoA + H2O = (R)-citramalate + CoA.	tmpzr1t_l9r_go_relaxed.owl	citramalate synthase				EC:2.3.1.182|RHEA:19045|MetaCyc:RXN-7743									molecular_function											owl:Class	
GO:0034874	biolink:NamedThing	thioacetamide S-oxide S-oxygenase activity	Catalysis of the reaction: thioacetamide S-oxide + O2 + 2 H+ + 2 e- = thioacetamide S,S-dioxide + H2O.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r1313									molecular_function											owl:Class	
GO:0034942	biolink:NamedThing	cis-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity	Catalysis of the reaction: cis-2-methyl-5-isopropylhexa-2,5-dienoic acid + ATP + CoASH = cis-2-methyl-5-isopropylhexa-2,5-dienoyl-CoA + AMP + PPi.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0988									molecular_function											owl:Class	
GO:0052614	biolink:NamedThing	uracil oxygenase activity	Catalysis of the reaction: uracil + NADH + O2 + H+ = ureidoacrylate peracid + NAD+. Ureidoacrylate peracid is spontaneously reduced by NADH to form ureidoacrylate.	tmpzr1t_l9r_go_relaxed.owl	pyrimidine oxygenase activity				RHEA:31587|MetaCyc:RXN0-6444				2010-08-26T10:11:11Z					molecular_function											owl:Class	
GO:0034897	biolink:NamedThing	4-(1-ethyl-1,4-dimethyl-pentyl)phenol monooxygenase activity	Catalysis of the reaction: 4-(1-ethyl-1,4-dimethyl-pentyl)phenol + O2 + 2 H+ + 2 e- = hydroquinone + 3,6-dimethylheptan-3-ol.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r1358									molecular_function											owl:Class	
GO:0071581	biolink:NamedThing	regulation of zinc ion transmembrane import	Any process that modulates the frequency, rate or extent of zinc ion import.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-01-28T03:09:19Z					biological_process											owl:Class	
GO:0047718	biolink:NamedThing	indanol dehydrogenase activity	Catalysis of the reaction: indan-1-ol + NAD(P)+ = indanone + NAD(P)H + H+.	tmpzr1t_l9r_go_relaxed.owl	indan-1-ol:NAD(P)+ 1-oxidoreductase activity				EC:1.1.1.112|MetaCyc:INDANOL-DEHYDROGENASE-RXN									molecular_function											owl:Class	
GO:0070551	biolink:NamedThing	endoribonuclease activity, cleaving siRNA-paired mRNA	Catalysis of the endonucleolytic cleavage of the mRNA in a double-stranded RNA molecule formed by the base pairing of an mRNA with an siRNA, yielding 5'-phosphomonoesters.	tmpzr1t_l9r_go_relaxed.owl	argonaute endoribonuclease activity													molecular_function											owl:Class	
GO:0047472	biolink:NamedThing	3-carboxy-cis,cis-muconate cycloisomerase activity	Catalysis of the reaction: 2-(carboxymethyl)-5-oxo-2,5-dihydro-2-furoate = 3-carboxy-cis,cis-muconate + H(+).	tmpzr1t_l9r_go_relaxed.owl	beta-carboxymuconate lactonizing enzyme activity|3-carboxymuconate cycloisomerase type II activity|3-carboxymuconolactone hydrolase activity|3-carboxymuconate lactonizing enzyme activity|CMLE activity	https://github.com/geneontology/go-ontology/issues/21794			UM-BBD_reactionID:r0582|KEGG_REACTION:R03307|RHEA:23656|MetaCyc:5.5.1.2-RXN|EC:5.5.1.2							GO:0018842		molecular_function											owl:Class	
GO:0044677	biolink:NamedThing	methyl-tetrahydromethanopterin:coenzyme M methyltransferase complex	A protein complex consisted of eight polypeptides. This complex catalyzes the formation of methyl-coenzyme M and H4MPT from N5-methyl-H4MPT and CoM during methanogenesis.	tmpzr1t_l9r_go_relaxed.owl	methyl-H4MPT|5-methyl-5,6,7,8-tetrahydromethanopterin:2-mercaptoethane sulfonate 2-methyltransferase complex|N5-methyltetrahydromethanopterin-coenzyme M methyltransferase complex|coenzyme M methyltransferase complex							jl	2012-08-09T10:58:24Z					cellular_component											owl:Class	
GO:0103045	biolink:NamedThing	methione N-acyltransferase activity	Catalysis of the reaction: L-methionine  + acetyl-CoA = N-acetyl-L-methionine + coenzyme A + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN0-6948|EC:2.3.1.1|RHEA:44144									molecular_function											owl:Class	
GO:0008976	biolink:NamedThing	polyphosphate kinase activity	Catalysis of the reaction: ATP + phosphate(n) = ADP + phosphate(n+1).	tmpzr1t_l9r_go_relaxed.owl	ATP-polyphosphate phosphotransferase activity|polyphosphate polymerase activity|polyphosphoric acid kinase activity|ATP:polyphosphate phosphotransferase activity				EC:2.7.4.1|MetaCyc:POLYPHOSPHATE-KINASE-RXN|RHEA:19573									molecular_function											owl:Class	
GO:1902434	biolink:NamedThing	sulfate import across plasma membrane	The directed movement of sulfate from outside of a cell, across the plasma membrane and into the cytosol.	tmpzr1t_l9r_go_relaxed.owl	sulphate import into cell|sulfate import into cell							mah	2013-10-07T14:12:38Z					biological_process											owl:Class	
GO:1990599	biolink:NamedThing	3' overhang single-stranded DNA endodeoxyribonuclease activity	Catalysis of the hydrolysis of ester linkages within 3' overhang single-stranded deoxyribonucleic acid by creating internal breaks.	tmpzr1t_l9r_go_relaxed.owl								al	2015-01-06T15:21:28Z					molecular_function											owl:Class	
GO:1904473	biolink:NamedThing	response to L-dopa	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-dopa stimulus.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-07-09T20:15:53Z					biological_process											owl:Class	
GO:0061126	biolink:NamedThing	positive regulation of positive chemotaxis to cAMP by DIF-1	Any process that increases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of DIF-1. DIF-1 is a chlorinated alkylphenone.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-05-17T08:41:04Z					biological_process											owl:Class	
GO:0008886	biolink:NamedThing	glyceraldehyde-3-phosphate dehydrogenase (NADP+) (non-phosphorylating) activity	Catalysis of the reaction: D-glyceraldehyde 3-phosphate + H(2)O + NADP(+) = 3-phospho-D-glycerate + 2 H(+) + NADPH.	tmpzr1t_l9r_go_relaxed.owl	NADP-glyceraldehyde-3-phosphate dehydrogenase activity|D-glyceraldehyde-3-phosphate:NADP+ oxidoreductase activity|glyceraldehyde 3-phosphate dehydrogenase (NADP)|dehydrogenase, glyceraldehyde phosphate (nicotinamide adenine dinucleotide phosphate)|nonphosphorylating glyceraldehyde-3-phosphate dehydrogenase activity|triosephosphate dehydrogenase activity|NADP-glyceraldehyde phosphate dehydrogenase|glyceraldehyde phosphate dehydrogenase (NADP)|glyceraldehyde-3-phosphate:NADP reductase activity|glyceraldehyde-3-phosphate dehydrogenase (NADP)				KEGG_REACTION:R01058|EC:1.2.1.9|MetaCyc:1.2.1.9-RXN|RHEA:14669									molecular_function											owl:Class	
GO:0098646	biolink:NamedThing	collagen sheet	A protein complex that consists of collagen triple helices associated to form a sheet-like network.	tmpzr1t_l9r_go_relaxed.owl	collagen hexagonal network													cellular_component											owl:Class	
GO:0009578	biolink:NamedThing	etioplast stroma	The space enclosed by the double membrane of an etioplast but excluding the prothylakoid space. It contains the etioplast DNA.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0102585	biolink:NamedThing	cyanidin 3-O-[2''-O-(xylosyl)-6''-O-(p-coumaroyl) glucoside] 5-O-glucoside malonyltransferase activity	Catalysis of the reaction: cyanidin 3-O-[2''-O-(xylosyl)-6''-O-(p-coumaroyl) glucoside] 5-O-glucoside + malonyl-CoA + H+ <=> cyanidin 3-O-[2''-O-(xylosyl)-6''-O-(p-coumaroyl) glucoside] 5-O-malonylglucoside + coenzyme A.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-15331									molecular_function											owl:Class	
GO:0071968	biolink:NamedThing	lipid A-core heptosyltransferase activity	Catalysis of the reaction: galactosyl-glucosyl3-heptosyl3-KDO2-lipid A-bisphosphate + ADP-L-glycero-beta-D-manno-heptose = lipid A-core + ADP + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN0-5127|RHEA:30019			mah	2010-10-14T05:15:22Z					molecular_function											owl:Class	
GO:0001156	biolink:NamedThing	TFIIIC-class transcription factor complex binding	Binding to a general RNA polymerase III transcription factor belonging to the TFIIC complex, one of the factors involved in formation of the preinitiation complex (PIC) by RNA polymerase III.	tmpzr1t_l9r_go_relaxed.owl	TFIIIC-class transcription factor binding							krc	2011-01-27T05:02:22Z					molecular_function											owl:Class	
GO:0018379	biolink:NamedThing	cytochrome c-heme linkage via heme-bis-L-cysteine	The linkage of cytochromes and other heme proteins to heme via heme-bis-L-cysteine.	tmpzr1t_l9r_go_relaxed.owl	cytochrome c-haem linkage via haem-bis-L-cysteine				RESID:AA0134									biological_process											owl:Class	
GO:0070941	biolink:NamedThing	eisosome assembly	The aggregation, arrangement and bonding together of a set of components to form an eisosome, a cell part that is composed of the eisosome membrane and eisosome filaments. The eisosome membrane, also called the MCC domain, is a furrow-like plasma membrane sub-domain with associated integral transmembrane proteins. The eisosome filaments form a scaffolding lattice on the cytoplasmic face of the membrane.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-09-30T02:49:30Z					biological_process											owl:Class	
GO:0015535	biolink:NamedThing	fucose:proton symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: fucose(out) + H+(out) = fucose(in) + H+(in).	tmpzr1t_l9r_go_relaxed.owl	fucose:hydrogen symporter activity				RHEA:29023									molecular_function											owl:Class	
GO:0048623	biolink:NamedThing	seed germination on parent plant	The process in which a seed germinates before being shed from the parent plant.	tmpzr1t_l9r_go_relaxed.owl	non-vegetative vivipary|vivipary|pre-harvest sprouting													biological_process											owl:Class	
GO:0019727	biolink:NamedThing	mevaldate reductase (NAD+) activity	Catalysis of the reaction: (R)-mevalonate + NAD(+) = H(+) + mevaldate + NADH.	tmpzr1t_l9r_go_relaxed.owl					KEGG_REACTION:R02246|MetaCyc:MEVALDATE-REDUCTASE-RXN|EC:1.1.1.32|RHEA:13221									molecular_function											owl:Class	
GO:0035527	biolink:NamedThing	3-hydroxypropionate dehydrogenase (NADP+) activity	Catalysis of the reaction: 3-hydroxypropanoate + NADP+ = 3-oxopropanoate + H+ + NADPH.	tmpzr1t_l9r_go_relaxed.owl	3-hydroxypropanoate dehydrogenase (NADP+) activity|3-hydroxypropanoate:NADP+ oxidoreductase|3-hydroxypropionate:NADP+ oxidoreductase				RHEA:26438|EC:1.1.1.298|MetaCyc:RXN-8974|KEGG_REACTION:R09289			bf	2010-05-05T10:55:07Z					molecular_function											owl:Class	
GO:0003086	biolink:NamedThing	regulation of systemic arterial blood pressure by local renal renin-angiotensin	The process in which angiotensinogen metabolites in the kidney modulate the force with which blood passes through the renal circulatory system. The process begins when renin cleaves angiotensinogen.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0022009	biolink:NamedThing	central nervous system vasculogenesis	The differentiation of endothelial cells from progenitor cells during blood vessel development, and the de novo formation of blood vessels and tubes in the central nervous system. The capillary endothelial cells in the brain are specialized to form the blood-brain barrier.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/21480												biological_process											owl:Class	
GO:0008719	biolink:NamedThing	dihydroneopterin triphosphate 2'-epimerase activity	Catalysis of the reaction: dihydroneopterin triphosphate = dihydromonapterin-triphosphate.	tmpzr1t_l9r_go_relaxed.owl	D-erythro-7,8-dihydroneopterin triphosphate 2'-epimerase activity				RHEA:28346|MetaCyc:H2NTPEPIM-RXN|EC:5.1.99.7									molecular_function											owl:Class	
GO:0048006	biolink:NamedThing	antigen processing and presentation, endogenous lipid antigen via MHC class Ib	The process in which an antigen-presenting cell expresses lipid antigen of endogenous origin in association with an MHC class Ib protein complex on its cell surface. Class Ib here refers to non-classical class I molecules, such as those of the CD1 family.	tmpzr1t_l9r_go_relaxed.owl	antigen presentation, endogenous lipid antigen|endogenous lipid antigen processing and presentation via MHC class Ib													biological_process											owl:Class	
GO:0140675	biolink:NamedThing	ATP-dependent histone unloader activity	Removing a histone or a histone complex from DNA.	tmpzr1t_l9r_go_relaxed.owl	histone unloader activity|histone unloading activity	https://github.com/geneontology/go-ontology/issues/21733						pg	2021-06-29T12:43:10Z					molecular_function											owl:Class	
GO:0099586	biolink:NamedThing	release of sequestered calcium ion into postsynaptic cytosol	The process in which calcium ions sequestered in the endoplasmic reticulum, Golgi apparatus or mitochondria are released into the postsynaptic cytosol.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0019822	biolink:NamedThing	P4 peroxisome	A subform of peroxisome that corresponds to an intermediate in a peroxisome assembly pathway, which operates by conversion of peroxisomal subforms in the direction P1, P2 -> P3 -> P4 -> P5 -> P6. P4 peroxisomes are distinguished from the other subforms on the bases of buoyant density and protein content.	tmpzr1t_l9r_go_relaxed.owl	peroxisome vesicle					Note that this peroxisome assembly pathway is described in the yeast Yarrowia lipolytica. See also the cellular component terms 'P1 peroxisome ; GO:0019819', 'P2 peroxisome ; GO:0019820', 'P3 peroxisome ; GO:0019821', 'P5 peroxisome ; GO:0019823', and 'P6 peroxisome ; GO:0019824'.								cellular_component											owl:Class	
GO:0099096	biolink:NamedThing	vestibular calyx terminal	The giant, cup-shaped axon terminal of a vestibular afferent neuron, serving as a post-synaptic contact to a type I hair cell.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0102915	biolink:NamedThing	piperitol synthase activity	Catalysis of the reaction: H+ + (+)-pinoresinol + NADPH + O2 <=> (+)-piperitol + NADP + 2 H2O.	tmpzr1t_l9r_go_relaxed.owl					RHEA:56776|EC:1.14.19.74|MetaCyc:RXN-8695									molecular_function											owl:Class	
GO:0051749	biolink:NamedThing	indole acetic acid carboxyl methyltransferase activity	Catalysis of the reaction: indole acetic acid + S-adenosyl-methionine = methyl indole acetic acid ester + S-adenosyl-homocysteine.	tmpzr1t_l9r_go_relaxed.owl	IAA carboxyl methyltransferase activity													molecular_function											owl:Class	
GO:0018526	biolink:NamedThing	2-aminobenzoyl-CoA reductase activity	Catalysis of the reaction: 2-aminobenzoyl-CoA + 2 H+ + 2 e- = NH3 + benzoyl-CoA.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0342									molecular_function											owl:Class	
GO:0003298	biolink:NamedThing	physiological muscle hypertrophy	The enlargement or overgrowth of all or part of a muscle organ or tissue due to an increase in the size of its muscle cells. Physiological hypertrophy is a normal process during development.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-10-22T09:24:51Z					biological_process											owl:Class	
GO:0098986	biolink:NamedThing	T-bar	A T-shaped presynpatic density.  These are common in arhropod central nervous systems.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0034802	biolink:NamedThing	branched-chain dodecylbenzene sulfonate monooxygenase activity	Catalysis of the reaction: branched-chain dodecylbenzene sulfonate + 1/2 O2 + H+ = sulfurous acid + branched-chain dodecyl-4-hydroxy-benzene + sulfite.	tmpzr1t_l9r_go_relaxed.owl					EC:1.14.13.-|UM-BBD_reactionID:r1079									molecular_function											owl:Class	
GO:1990258	biolink:NamedThing	histone glutamine methylation	The modification of a histone by addition of a methyl group to an glutamine residue.	tmpzr1t_l9r_go_relaxed.owl								sp	2014-01-02T15:08:02Z					biological_process											owl:Class	
GO:0047143	biolink:NamedThing	chlorate reductase activity	Catalysis of the reaction: AH(2) + chlorate = A + chlorite + H(2)O + H(+).	tmpzr1t_l9r_go_relaxed.owl	chlorate reductase C|chlorite:acceptor oxidoreductase activity				EC:1.97.1.1|UM-BBD_reactionID:r0981|MetaCyc:1.97.1.1-RXN|RHEA:16349|KEGG_REACTION:R03575									molecular_function											owl:Class	
GO:0047921	biolink:NamedThing	aminoglycoside 2'-N-acetyltransferase activity	Catalysis of the reaction: acetyl-CoA + gentamicin C(1a) = N(2')-acetylgentamicin C(1a) + CoA + H(+). This is acetylation of the 2'-amino group of the 6-deoxy-6-aminoglucose ring.	tmpzr1t_l9r_go_relaxed.owl	acetyl-CoA:gentamicin-C1a N2'-acetyltransferase activity|gentamycin acetyltransferase II|gentamycin 2'-N-acetyltransferase activity|gentamicin acetyltransferase II activity|gentamicin 2'-N-acetyltransferase activity|acetyl-CoA:gentamycin-C1a N2'-acetyltransferase activity				KEGG_REACTION:R03056|RHEA:24516|EC:2.3.1.59|MetaCyc:GENTAMICIN-2-N-ACETYLTRANSFERASE-RXN									molecular_function											owl:Class	
GO:0048484	biolink:NamedThing	enteric nervous system development	The process whose specific outcome is the progression of the enteric nervous system over time, from its formation to the mature structure. The enteric nervous system is composed of two ganglionated neural plexuses in the gut wall which form one of the three major divisions of the autonomic nervous system. The enteric nervous system innervates the gastrointestinal tract, the pancreas, and the gall bladder. It contains sensory neurons, interneurons, and motor neurons. Thus the circuitry can autonomously sense the tension and the chemical environment in the gut and regulate blood vessel tone, motility, secretions, and fluid transport. The system is itself governed by the central nervous system and receives both parasympathetic and sympathetic innervation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0035624	biolink:NamedThing	receptor transactivation	The process in which a receptor is activated by another receptor. Receptor transactivation can occur through different mechanisms and includes cross-talk between signaling pathways where one receptor activates a receptor for a different ligand, and also activation of subunits within a receptor oligomer.	tmpzr1t_l9r_go_relaxed.owl								bf	2010-12-08T04:18:18Z					biological_process											owl:Class	
GO:0031404	biolink:NamedThing	chloride ion binding	Binding to a chloride ion (Cl-).	tmpzr1t_l9r_go_relaxed.owl	chloride binding|Cl- ion binding													molecular_function											owl:Class	
GO:0070156	biolink:NamedThing	mitochondrial phenylalanyl-tRNA aminoacylation	The process of coupling phenylalanine to phenylalanyl-tRNA in a mitochondrion, catalyzed by phenylalanyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0035187	biolink:NamedThing	hatching behavior	The specific behavior of an organism during the emergence from an egg shell. In Drosophila for example, the larva swings its head reiteratively through a semicircular arc, using its mouth hooks to tear apart the chorion in front of it and thus free itself from within the egg shell.	tmpzr1t_l9r_go_relaxed.owl	hatching behaviour													biological_process											owl:Class	
GO:0102763	biolink:NamedThing	phytyl-P kinase activity	Catalysis of the reaction: phytyl phosphate(2-) + a nucleoside triphosphate <=> (E)-3,7,11,15-tetramethylhexadec-2-en-1-yl diphosphate + a nucleoside diphosphate.	tmpzr1t_l9r_go_relaxed.owl					RHEA:38099|MetaCyc:RXN-7763									molecular_function											owl:Class	
GO:0003848	biolink:NamedThing	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity	Catalysis of the reaction: 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine + ATP = (2-amino-4-hydroxy-7,8-dihydropteridin-6-yl)methyl diphosphate + AMP + 2 H(+).	tmpzr1t_l9r_go_relaxed.owl	7,8-dihydroxymethylpterin-pyrophosphokinase activity|7,8-dihydro-6-hydroxymethylpterin pyrophosphokinase activity|H2-pteridine-CH2OH pyrophosphokinase activity|6-hydroxymethyl-7,8-dihydropterin diphosphokinase activity|ATP:2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine 6'-diphosphotransferase activity|7,8-dihydro-6-hydroxymethylpterin diphosphokinase activity|hydroxymethyldihydropteridine pyrophosphokinase activity|6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase activity|HPPK|2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase activity				KEGG_REACTION:R03503|EC:2.7.6.3|MetaCyc:H2PTERIDINEPYROPHOSPHOKIN-RXN|RHEA:11412									molecular_function											owl:Class	
GO:0050553	biolink:NamedThing	taxadiene synthase activity	Catalysis of the reaction: all-trans-geranylgeranyl diphosphate = diphosphate + taxa-4,11-diene.	tmpzr1t_l9r_go_relaxed.owl	geranylgeranyl-diphosphate diphosphate-lyase (cyclizing, taxadiene-forming)|taxa-4(5),11(12)-diene synthase activity|geranylgeranyl-diphosphate diphosphate-lyase (cyclizing, taxa-4,11-diene-forming)				MetaCyc:4.2.3.17-RXN|RHEA:20912|KEGG_REACTION:R06305|EC:4.2.3.17									molecular_function											owl:Class	
GO:0036341	biolink:NamedThing	chitin-based cuticle sclerotization by protein cross-linking	The process of hardening of a chitin-based cuticle by protein cross-linking, and the incorporation of phenolic precursors. This mechanism of cuticle hardening occurs in insects and is usually accompanied by darkening of the cuticle.	tmpzr1t_l9r_go_relaxed.owl	chitin-based cuticle sclerotization by protein cross-linking and cuticle tanning							bf	2012-09-11T13:51:46Z					biological_process											owl:Class	
GO:0097189	biolink:NamedThing	apoptotic body	A vesicle containing parts of a dying cell. Apoptotic bodies can be formed during the execution phase of the apoptotic process, when the cell's cytoskeleton breaks up and causes the membrane to bulge outward. These bulges may separate from the cell, taking a portion of cytoplasm with them, to become apoptotic bodies. These are then engulfed by phagocytic cells, and their components recycled. Apoptotic bodies may range in size from 0.8 to 5um.	tmpzr1t_l9r_go_relaxed.owl	apoptotic vesicle|apoptotic bleb							pr	2011-11-22T08:05:20Z					cellular_component											owl:Class	
GO:0031900	biolink:NamedThing	chromoplast outer membrane	The outer, i.e. cytoplasm-facing, lipid bilayer of the chromoplast envelope.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0097009	biolink:NamedThing	energy homeostasis	Any process involved in the balance between food intake (energy input) and energy expenditure.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of energy homeostasis|positive regulation of energy homeostasis|regulation of energy homeostasis							pr	2011-03-21T10:52:44Z			GO:2000507|GO:2000505|GO:2000506		biological_process											owl:Class	
GO:0060486	biolink:NamedThing	club cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a club cell. A club cell is an unciliated epithelial cell found in the respiratory and terminal bronchioles.	tmpzr1t_l9r_go_relaxed.owl	Clara cell differentiation													biological_process											owl:Class	
GO:0047600	biolink:NamedThing	abequosyltransferase activity	Catalysis of the reaction: CDP-abequose + D-mannosyl-L-rhamnosyl-D-galactose-1-diphospholipid = CDP + D-abequosyl-D-mannosyl-rhamnosyl-D-galactose-1-diphospholipid.	tmpzr1t_l9r_go_relaxed.owl	CDP-abequose:D-mannosyl-L-rhamnosyl-D-galactose-1-diphospholipid D-abequosyltransferase activity|trihexose diphospholipid abequosyltransferase activity				RHEA:34183|MetaCyc:ABEQUOSYLTRANSFERASE-RXN|EC:2.4.1.60									molecular_function											owl:Class	
GO:0018700	biolink:NamedThing	2-chloro-N-isopropylacetanilide reductive dehalogenase activity	Catalysis of the reaction: 2-chloro-N-isopropylacetanilide + H+ + 2 e- = Cl- + N-isopropylacetanilide.	tmpzr1t_l9r_go_relaxed.owl					EC:1.97.1.-|UM-BBD_reactionID:r0719									molecular_function											owl:Class	
GO:0047186	biolink:NamedThing	N-acetylneuraminate 7-O(or 9-O)-acetyltransferase activity	Catalysis of the reaction: N-acetylneuraminate + acetyl-CoA = N-acetyl-7-O(or 9-O)-acetylneuraminate + CoA.	tmpzr1t_l9r_go_relaxed.owl	glycoprotein 7(9)-O-acetyltransferase activity|acetyl-CoA:N-acetylneuraminate-7- or 8-O-acetyltransferase activity|sialate O-acetyltransferase|acetyl-CoA:N-acetylneuraminate-7- and/or 8-O-acetyltransferase activity|N-acetylneuraminate 7,8-O-acetyltransferase activity|acetyl-CoA:N-acetylneuraminate 7-O(or 9-O)-acetyltransferase activity|acetyl-CoA:N-acetylneuraminate-9(7)-O-acetyltransferase activity|N-acetylneuraminate 7(8)-O-acetyltransferase activity|acetyl-CoA:N-acetylneuraminate-9(or 7)-O-acetyltransferase activity|N-acetylneuraminate O7-(or O9-)acetyltransferase activity				RHEA:20808|EC:2.3.1.45|MetaCyc:2.3.1.45-RXN									molecular_function											owl:Class	
GO:0071130	biolink:NamedThing	alpha5-beta1 integrin-LPP3 complex	A protein complex that consists of an alpha5-beta1 integrin complex bound to lipid phosphate phosphohydrolase-3.	tmpzr1t_l9r_go_relaxed.owl	ITGA5-ITGB1-PPAP2B complex							mah	2009-11-13T02:25:47Z					cellular_component											owl:Class	
GO:0110135	biolink:NamedThing	Norrin signaling pathway	The series of molecular signals initiated by binding of the cysteine knot protein Norrin to a Frizzled 4 (Fzd4) family receptor on the surface of the target cell and ending with a change in cell state.	tmpzr1t_l9r_go_relaxed.owl								kmv	2019-01-18T19:07:18Z					biological_process											owl:Class	
GO:1905370	biolink:NamedThing	serine-type endopeptidase complex	A protein complex which is capable of serine-type endopeptidase activity.	tmpzr1t_l9r_go_relaxed.owl						An example of this is PLAU in human (UniProt symbol P00749) in PMID:1689240 (inferred from direct assay).		bhm	2016-08-16T13:09:57Z					cellular_component											owl:Class	
GO:0047906	biolink:NamedThing	fucosterol-epoxide lyase activity	Catalysis of the reaction: (24R,24'R)-fucosterol epoxide = acetaldehyde + desmosterol.	tmpzr1t_l9r_go_relaxed.owl	(24R,24'R)-fucosterol-epoxide acetaldehyde-lyase activity|(24R,24'R)-fucosterol-epoxide acetaldehyde-lyase (desmosterol-forming)				EC:4.1.2.33|MetaCyc:FUCOSTEROL-EPOXIDE-LYASE-RXN|RHEA:10884|KEGG_REACTION:R03723									molecular_function											owl:Class	
GO:0034029	biolink:NamedThing	2-oxoglutarate carboxylase activity	Catalysis of the reaction: 2-oxoglutarate + ATP + bicarbonate = ADP + 2 H(+) + oxalosuccinate + phosphate.	tmpzr1t_l9r_go_relaxed.owl	oxalosuccinate synthetase activity|CFI|carboxylating factor for ICDH|OGC				KEGG_REACTION:R08201|RHEA:20425|MetaCyc:RXN-8457|EC:6.4.1.7									molecular_function											owl:Class	
GO:0006592	biolink:NamedThing	ornithine biosynthetic process	The chemical reactions and pathways resulting in the formation of ornithine, an amino acid only rarely found in proteins, but which is important in living organisms as an intermediate in the reactions of the urea cycle and in arginine biosynthesis.	tmpzr1t_l9r_go_relaxed.owl	ornithine anabolism|ornithine formation|ornithine synthesis|ornithine biosynthesis													biological_process											owl:Class	
GO:0047866	biolink:NamedThing	dimethylglycine oxidase activity	Catalysis of the reaction: N,N-dimethylglycine + H(2)O + O(2) = formaldehyde + H(2)O(2) + sarcosine.	tmpzr1t_l9r_go_relaxed.owl	N,N-dimethylglycine:oxygen oxidoreductase (demethylating)				MetaCyc:DIMETHYLGLYCINE-OXIDASE-RXN|KEGG_REACTION:R01564|RHEA:17077|EC:1.5.3.10									molecular_function											owl:Class	
GO:0047772	biolink:NamedThing	carboxymethyloxysuccinate lyase activity	Catalysis of the reaction: carboxymethoxysuccinate = fumarate + glycolate.	tmpzr1t_l9r_go_relaxed.owl	carboxymethyloxysuccinate glycolate-lyase activity|carboxymethyloxysuccinate glycolate-lyase (fumarate-forming)				RHEA:12336|MetaCyc:CARBOXYMETHYLOXYSUCCINATE-LYASE-RXN|EC:4.2.99.12|KEGG_REACTION:R01336									molecular_function											owl:Class	
GO:0099014	biolink:NamedThing	neuronal dense core vesicle organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a neuronal dense core vesicle.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0071269	biolink:NamedThing	L-homocysteine biosynthetic process	The chemical reactions and pathways resulting in the formation of L-homocysteine, the L-enantiomer of 2-amino-4-sulfanylbutanoic acid.	tmpzr1t_l9r_go_relaxed.owl	L-homocysteine biosynthesis|L-homocysteine synthesis|L-homocysteine anabolism|L-homocysteine formation							mah	2009-12-09T05:36:37Z					biological_process											owl:Class	
GO:0046366	biolink:NamedThing	allose biosynthetic process	The chemical reactions and pathways resulting in the formation of allose, allo-hexose, an aldohexose similar to glucose, differing only in the configuration of the hydroxyl group of C-3.	tmpzr1t_l9r_go_relaxed.owl	allose anabolism|allose biosynthesis|allose synthesis|allose formation													biological_process											owl:Class	
GO:0004837	biolink:NamedThing	tyrosine decarboxylase activity	Catalysis of the reaction: L-tyrosine = tyramine + CO2.	tmpzr1t_l9r_go_relaxed.owl	L-tyrosine carboxy-lyase activity|L-(-)-tyrosine apodecarboxylase activity|L-tyrosine decarboxylase activity|L-tyrosine carboxy-lyase (tyramine-forming)				MetaCyc:TYROSINE-DECARBOXYLASE-RXN|RHEA:14345|EC:4.1.1.25									molecular_function											owl:Class	
GO:0048188	biolink:NamedThing	Set1C/COMPASS complex	A conserved protein complex that catalyzes methylation of histone H3. In Saccharomyces the complex contains Shg1p, Sdc1p, Swd1p, Swd2p, Swd3p, Spp1p, Bre2p, and the trithorax-related Set1p; in mammals it contains the catalytic subunit (SETD1A or SETD1B), WDR5, WDR82, RBBP5, ASH2L/ASH2, CXXC1/CFP1, HCFC1 and DPY30.	tmpzr1t_l9r_go_relaxed.owl	COMPASS complex|Set1/COMPASS complex|Set1C													cellular_component											owl:Class	
GO:0051750	biolink:NamedThing	delta3,5-delta2,4-dienoyl-CoA isomerase activity	Catalysis of the isomerization of 3,5-dienoyl-CoA to 2,4-dienoyl-CoA.	tmpzr1t_l9r_go_relaxed.owl	delta5-delta2,4-dienoyl-CoA isomerase activity|delta(3,5),delta(2,4)-dienoyl-coenzyme A isomerase activity											GO:0008416		molecular_function											owl:Class	
GO:0002126	biolink:NamedThing	instrumental aggressive behavior	Aggressive behavior directed towards obtaining some goal, considered to be a learned response to a situation.	tmpzr1t_l9r_go_relaxed.owl	instrumental aggression													biological_process											owl:Class	
GO:0140563	biolink:NamedThing	UDP-D-xylose:beta-D-glucoside alpha-1,3-D-xylosyltransferase activity	Catalyzes the reaction: UDP-alpha-D-xylose + [protein with EGF-like domain]-3-O-(beta-D-glucosyl)-L-serine <=> UDP + [protein with EGF-like domain]-3-O-(alpha-D-xylosyl-(1->3)-beta-D-glucosyl)-L-serine.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/16869			RHEA:56064|EC:2.4.2.42			pg	2020-11-25T16:07:58Z					molecular_function											owl:Class	
GO:0043784	biolink:NamedThing	cob(II)yrinic acid a,c-diamide reductase activity	Catalysis of the reaction: 2 cob(I)yrinate a,c diamide + FMN + 3 H(+) = 2 cob(II)yrinate a,c diamide + FMNH(2).	tmpzr1t_l9r_go_relaxed.owl	cob(II)yrinic acid-a,c-diamide:FMN oxidoreductase activity				KEGG_REACTION:R05218|RHEA:24300|EC:1.16.8.1|MetaCyc:R343-RXN									molecular_function											owl:Class	
GO:0047765	biolink:NamedThing	caldesmon-phosphatase activity	Catalysis of the reaction: caldesmon phosphate + H2O = caldesmon + phosphate.	tmpzr1t_l9r_go_relaxed.owl	caldesmon-phosphate phosphohydrolase activity|SMP-I|smooth muscle caldesmon phosphatase activity				EC:3.1.3.55|MetaCyc:CALDESMON-PHOSPHATASE-RXN									molecular_function											owl:Class	
GO:0036357	biolink:NamedThing	2-phosphoglycerate kinase activity	Catalysis of the reaction: 2-phosphoglycerate + ATP = 2,3-diphosphoglycerate + ADP.	tmpzr1t_l9r_go_relaxed.owl	2PGK activity				EC:2.7.2.-	This reaction is the first step in the biosynthesis of cyclic 2,3-diphosphoglycerate (cDPG).		bf	2012-09-19T15:06:25Z					molecular_function											owl:Class	
GO:0080071	biolink:NamedThing	indol-3-yl-methyl-desulfoglucosinolate sulfotransferase activity	Catalysis of the reaction: indol-3-yl-methyl-desulfoglucosinolate + 3'-phosphoadenosine 5'-phosphosulfate = indol-3-yl-methyl-glucosinolate + adenosine 3',5'-bisphosphate.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-1443			dhl	2009-04-13T04:08:33Z					molecular_function											owl:Class	
GO:0016752	biolink:NamedThing	sinapoyltransferase activity	Catalysis of the transfer of a sinapoyl group to an acceptor molecule.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0009773	biolink:NamedThing	photosynthetic electron transport in photosystem I	A photosynthetic electron transport chain in which electrons move from the primary electron acceptor (Quinone, X) through a chain of electron transport molecules in the thylakoid membrane until they reach ferredoxin which passes the electron to the ultimate electron acceptor; NADP.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0102943	biolink:NamedThing	trans-2,3-dihydro-3-hydroxy-anthranilate isomerase activity	Catalysis of the reaction: (2S,3S)-2,3-dihydro-3-hydroxyanthranilic acid  = (1R,6S)-6-ammonio-5-oxocyclohex-2-ene-1-carboxylate.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-9031|RHEA:28182|EC:5.3.3.17									molecular_function											owl:Class	
GO:0047285	biolink:NamedThing	flavonol-3-O-glycoside xylosyltransferase activity	Catalysis of the reaction: flavonol 3-O-glycoside + UDP-D-xylose = flavonol 3-O-D-xylosylglycoside + UDP.	tmpzr1t_l9r_go_relaxed.owl	UDP-D-xylose:flavonol-3-O-glycoside 2''-O-beta-D-xylosyltransferase activity				EC:2.4.2.35|RHEA:19701|MetaCyc:2.4.2.35-RXN									molecular_function											owl:Class	
GO:0047083	biolink:NamedThing	5-O-(4-coumaroyl)-D-quinate 3'-monooxygenase activity	Catalysis of the reaction: O2 + NADPH + H+ + trans-5-O-(4-coumaroyl)-D-quinate = H2O + NADP+ + trans-5-O-caffeoyl-D-quinate.	tmpzr1t_l9r_go_relaxed.owl	coumaroylquinate(coumaroylshikimate) 3'-monooxygenase activity|trans-5-O-(4-coumaroyl)-D-quinate,NADPH:oxygen oxidoreductase (3'-hydroxylating)|5-O-(4-coumaroyl)-D-quinate/shikimate 3'-hydroxylase activity				MetaCyc:1.14.13.36-RXN|RHEA:16265|EC:1.14.14.96									molecular_function											owl:Class	
GO:0031836	biolink:NamedThing	neuromedin K receptor binding	Binding to a neuromedin K receptor.	tmpzr1t_l9r_go_relaxed.owl	neuromedin K receptor ligand|neurokinin-B receptor binding													molecular_function											owl:Class	
GO:0032517	biolink:NamedThing	SOD1-calcineurin complex	A protein complex formed by the association of superoxide dismutase 1 (SOD1) with calcineurin; complex formation is implicated in activation of calcineurin by SOD1.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0047690	biolink:NamedThing	aspartyltransferase activity	Catalysis of the reaction: L-asparagine + H(+) + hydroxylamine = beta-L-aspartylhydroxamate + NH(4)(+).	tmpzr1t_l9r_go_relaxed.owl	aspartotransferase activity|beta-aspartyl transferase activity|L-asparagine:hydroxylamine gamma-aspartyltransferase activity				RHEA:11252|EC:2.3.2.7|MetaCyc:ASPARTYLTRANSFERASE-RXN|KEGG_REACTION:R01485									molecular_function											owl:Class	
GO:0008613	biolink:NamedThing	diuretic hormone activity	The action characteristic of a diuretic hormone, a peptide hormone that, upon receptor binding, regulates water balance and fluid secretion.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0045228	biolink:NamedThing	slime layer polysaccharide biosynthetic process	The chemical reactions and pathways resulting in the formation of polysaccharides in the slime layer, a diffused layer of polysaccharide exterior to the bacterial cell wall.	tmpzr1t_l9r_go_relaxed.owl	slime layer polysaccharide biosynthesis|slime layer polysaccharide synthesis|slime layer polysaccharide anabolism|slime layer polysaccharide formation													biological_process											owl:Class	
GO:0045231	biolink:NamedThing	slime layer organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a slime layer. A slime layer is an easily removed, diffuse, unorganized layer of extracellular material that surrounds a cell.	tmpzr1t_l9r_go_relaxed.owl	slime layer organization and biogenesis|slime layer organisation													biological_process											owl:Class	
GO:0047937	biolink:NamedThing	glucose-1-phosphate phosphodismutase activity	Catalysis of the reaction: 2 D-glucose 1-phosphate = D-glucose + D-glucose 1,6-bisphosphate.	tmpzr1t_l9r_go_relaxed.owl	D-glucose-1-phosphate:D-glucose-1-phosphate 6-phosphotransferase activity|phosphodismutase activity|glucose 1-phosphate transphosphorylase activity				RHEA:16397|EC:2.7.1.41|MetaCyc:GLUCOSE-1-PHOSPHATE-PHOSPHODISMUTASE-RXN									molecular_function											owl:Class	
GO:0032983	biolink:NamedThing	kainate selective glutamate receptor complex	An assembly of four or five subunits which form a structure with an extracellular N-terminus and a large loop that together form the ligand binding domain. The C-terminus is intracellular. The ionotropic glutamate receptor complex itself acts as a ligand gated ion channel; on binding glutamate, charged ions pass through a channel in the center of the receptor complex. Kainate receptors are multimeric assemblies of GluK1-3 (also called GluR5-7), GluK4 (KA1) and GluK5 (KA2) subunits.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0071949	biolink:NamedThing	FAD binding	Binding to the oxidized form, FAD, of flavin-adenine dinucleotide, the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes.	tmpzr1t_l9r_go_relaxed.owl	oxidized flavin adenine dinucleotide binding|oxidized flavine-adenine dinucleotide binding							mah	2010-10-07T12:30:28Z					molecular_function											owl:Class	
GO:0031842	biolink:NamedThing	type 1 neuropeptide Y receptor binding	Binding to a type 1 neuropeptide Y receptor.	tmpzr1t_l9r_go_relaxed.owl	type 1 neuropeptide Y receptor ligand													molecular_function											owl:Class	
GO:0140665	biolink:NamedThing	ATP-dependent H3-H4 histone complex loader activity	Loading of a histone H3-H4 complex onto DNA, driven by ATP hydrolysis.	tmpzr1t_l9r_go_relaxed.owl	histone H3-H4 dimer loading activity|H3-H4 dimer loading activity|histone chaperone|H3-H4 histone complex loader activity|H3-H4 histone chaperone	https://github.com/geneontology/go-ontology/issues/21733|https://github.com/geneontology/go-ontology/issues/21580						pg	2021-06-22T13:57:16Z					molecular_function											owl:Class	
GO:0097681	biolink:NamedThing	double-strand break repair via alternative nonhomologous end joining	An instance of double-strand break repair via nonhomologous end joining that is independent of factors important for V(D)J recombination (as opposed to classical nonhomologous end joining). It often results in a deletion with microhomology (i.e. 5-25bp homology) at the repair junction. Among different subclasses of nonhomologous end joining (NHEJ), alternative NHEJ appears to play a significant role in the etiology of mutations that arise during cancer development and treatment.	tmpzr1t_l9r_go_relaxed.owl	alt-NHEJ|MMEJ|A-NHEJ|double-strand break repair via microhomology-mediated end joining							pr	2014-12-17T15:17:45Z					biological_process											owl:Class	
GO:0102681	biolink:NamedThing	isoamylase (maltodextrin-releasing) activity	Catalysis of the reaction: n H2O + a glycogen <=> n a maltodextrin.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-4301									molecular_function											owl:Class	
GO:0033390	biolink:NamedThing	putrescine biosynthetic process from arginine via N-carbamoylputrescine	The chemical reactions and pathways resulting in the formation of putrescine, 1,4-diaminobutane, from other compounds, including arginine, via the intermediate N-carbamoylputrescine; in this pathway, arginine is converted to agmatine, and agmatine is converted to putrescine in two single enzymatic steps.	tmpzr1t_l9r_go_relaxed.owl	putrescine biosynthesis from arginine via N-carbamoylputrescine|putrescine anabolism from arginine via N-carbamoylputrescine|putrescine formation from arginine via N-carbamoylputrescine|putrescine synthesis from arginine via N-carbamoylputrescine													biological_process											owl:Class	
GO:0080015	biolink:NamedThing	sabinene synthase activity	Catalysis of the reaction: geranyl diphosphate = sabinene + diphosphate.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-5103|EC:4.2.3.-									molecular_function											owl:Class	
GO:0042761	biolink:NamedThing	very long-chain fatty acid biosynthetic process	The chemical reactions and pathways resulting in the formation of a fatty acid which has a chain length greater than C22.	tmpzr1t_l9r_go_relaxed.owl	very-long-chain fatty acid biosynthetic process|very-long-chain fatty acid anabolism|very-long-chain fatty acid synthesis|very-long-chain fatty acid biosynthesis|very-long-chain fatty acid formation				MetaCyc:PWY-5080									biological_process											owl:Class	
GO:0035529	biolink:NamedThing	NADH pyrophosphatase activity	Catalysis of the reaction: NADH + H2O = AMP + NMNH + 2 H+.	tmpzr1t_l9r_go_relaxed.owl	NADH pyrophosphohydrolase activity|NADH diphosphatase activity				EC:3.6.1.9|MetaCyc:RXN0-4401|KEGG_REACTION:R00103|Reactome:R-HSA-6809287			bf	2010-05-05T04:55:10Z					molecular_function											owl:Class	
GO:0016110	biolink:NamedThing	tetraterpenoid catabolic process	The chemical reactions and pathways resulting in the breakdown of tetraterpenoid compounds, terpenoids with eight isoprene units.	tmpzr1t_l9r_go_relaxed.owl	tetraterpene catabolic process|tetraterpenoid degradation|tetraterpenoid catabolism|tetraterpenoid breakdown|tetraterpene catabolism													biological_process											owl:Class	
GO:0097713	biolink:NamedThing	dolichol-phosphate-mannose synthase regulator activity	Binds to and modulates the activity of dolichol-phosphate-mannose synthase.	tmpzr1t_l9r_go_relaxed.owl								pr	2016-08-23T11:19:37Z					molecular_function											owl:Class	
GO:0102989	biolink:NamedThing	5-pentadecatrienylresorcinol synthase activity	Catalysis of the reaction: 3 H+ + 9,12,15-cis-hexadecatrienoyl-CoA + 3 malonyl-CoA(5-) <=> 5-(pentadeca-8,11,14-trien-1-yl)resorcinol + 4 coenzyme A + 4 carbon dioxide.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-9618									molecular_function											owl:Class	
GO:0102706	biolink:NamedThing	butein:oxygen oxidoreductase activity	Catalysis of the reaction: butein 4'-beta-D-glucoside + O2 = aureusidin 6-O-beta-glucoside + H2O + H+.	tmpzr1t_l9r_go_relaxed.owl					RHEA:34203|EC:1.21.3.6|MetaCyc:RXN-6242									molecular_function											owl:Class	
GO:0150088	biolink:NamedThing	multiple synapse bouton, contacting multiple dendrites	A single axon terminal bouton making contact onto two or more dendritic spines protruding from multiple dendrites.	tmpzr1t_l9r_go_relaxed.owl	type 2 multiple-synapse bouton|type 2 multiple spine synapse bouton|type 2 multi-synapse bouton|type 2 multisynapse bouton|type 2 multi-synaptic bouton|MSB2|type 2 multisynaptic bouton							bc	2018-08-08T13:31:43Z					cellular_component											owl:Class	
GO:1903102	biolink:NamedThing	1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate.	tmpzr1t_l9r_go_relaxed.owl	1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate biosynthesis|1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate anabolism|1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate formation|1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate synthesis							bhm	2014-06-04T14:14:36Z					biological_process											owl:Class	
GO:0044817	biolink:NamedThing	hydrogen generation via biophotolysis	The production of hydrogen which results from the dissociation by light of water into molecular hydrogen and oxygen. This process is observed in cyanobacteria and microalgae.	tmpzr1t_l9r_go_relaxed.owl	hydrogen biosynthesis via biophotolysis							jl	2013-10-22T14:36:54Z					biological_process											owl:Class	
GO:0031886	biolink:NamedThing	type 1 member 3 taste receptor binding	Binding to a type 1 member 3 taste receptor.	tmpzr1t_l9r_go_relaxed.owl	type 1 member 3 taste receptor ligand|sweet taste receptor binding													molecular_function											owl:Class	
GO:0052719	biolink:NamedThing	apurinic/apyrimidinic endoribonuclease activity	Catalysis of the hydrolysis of ester linkages immediately 5' to an apurinic/apyrimidinic (AP; also called abasic) site within a ribonucleic acid molecule by creating internal breaks, generating a single-strand break with 5'-ribose phosphate and 3'-hydroxyl ends.	tmpzr1t_l9r_go_relaxed.owl	abasic endoribonuclease activity|apyrimidinic endoribonuclease activity|apurinic endoribonuclease activity|AP endoribonuclease activity													molecular_function											owl:Class	
GO:0080108	biolink:NamedThing	S-alkylthiohydroximate lyase activity	Catalysis of the conversion of a S-alkylthiohydroximate to a thiohydroximate.	tmpzr1t_l9r_go_relaxed.owl	S-alkylthiohydroximate C-S lyase activity							dhl	2009-04-23T04:35:14Z					molecular_function											owl:Class	
GO:0004422	biolink:NamedThing	hypoxanthine phosphoribosyltransferase activity	Catalysis of the reaction: IMP + diphosphate = hypoxanthine + 5-phospho-alpha-D-ribose 1-diphosphate.	tmpzr1t_l9r_go_relaxed.owl	IMP:diphosphate phospho-D-ribosyltransferase activity|guanine-hypoxanthine phosphoribosyltransferase activity|inosinic pyrophosphorylase activity|HGPRTase activity|IMP pyrophosphorylase activity|inosinate pyrophosphorylase activity|IMP-GMP pyrophosphorylase activity|Transphosphoribosidase activity|hypoxanthine-guanine phosphoribosyltransferase activity|IMP diphosphorylase activity|inosine 5'-phosphate pyrophosphorylase activity|inosinic acid pyrophosphorylase activity|6-mercaptopurine phosphoribosyltransferase activity|6-hydroxypurine phosphoribosyltransferase activity|purine-6-thiol phosphoribosyltransferase activity|HPRT				RHEA:17973|KEGG_REACTION:R01132|EC:2.4.2.8|MetaCyc:HYPOXANPRIBOSYLTRAN-RXN|Reactome:R-HSA-74215									molecular_function											owl:Class	
GO:0044587	biolink:NamedThing	cellopentaose binding	Binding to a cellopentaose, an oligosaccharide consisting of four glucose residues resulting from hydrolysis of cellulose.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-04-24T04:57:01Z					molecular_function											owl:Class	
GO:0033702	biolink:NamedThing	(+)-trans-carveol dehydrogenase activity	Catalysis of the reaction: (1R,5S)-carveol + NAD(+) = (S)-carvone + H(+) + NADH.	tmpzr1t_l9r_go_relaxed.owl	(+)-trans-carveol:NAD+ oxidoreductase activity				MetaCyc:RXN-9397|RHEA:14825|KEGG_REACTION:R06117|EC:1.1.1.275									molecular_function											owl:Class	
GO:1990860	biolink:NamedThing	Pho85-Pho80 CDK-cyclin complex	A cyclin dependent kinase (CDK) complex that contains a kinase subunit and a regulatory cyclin subunit. An example of this complex in budding yeast S. cerevisiae consists of the Pho85 kinase and the Pho80 cyclin.	tmpzr1t_l9r_go_relaxed.owl								rb	2015-09-24T17:53:50Z					cellular_component											owl:Class	
GO:0047129	biolink:NamedThing	opine dehydrogenase activity	Catalysis of the reaction: (2S)-2-[(R)-1-carboxyethylamino]pentanoate + H(2)O + NAD(+) = L-2-aminopentanoate + H(+) + NADH + pyruvate.	tmpzr1t_l9r_go_relaxed.owl	(2S)-2-{[1-(R)-carboxyethyl]amino}pentanoate dehydrogenase (NAD, L-aminopentanoate-forming)|(2S)-2-{[1-(R)-carboxyethyl]amino}pentanoate:NAD+ oxidoreductase (L-aminopentanoate-forming)				KEGG_REACTION:R03732|EC:1.5.1.28|MetaCyc:1.5.1.28-RXN|RHEA:21592									molecular_function											owl:Class	
GO:1904608	biolink:NamedThing	response to monosodium L-glutamate	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monosodium L-glutamate stimulus.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-08-27T18:43:08Z					biological_process											owl:Class	
GO:1990306	biolink:NamedThing	RSP5-BUL ubiquitin ligase complex	A ubiquitin ligase complex consisting of RSP5 and BUL components. It polyubiquinates plasma membrane transporters and permeases, required for their endocytosis and subsequent degradation in the vacuole. BUL1 or BUL2, respectively, bind to the target protein, enabling ubiquitylation by Rsp5. Phosphorylation of BUL proteins results in binding to 14-3-3 proteins, protecting the permeases from down-regulation.	tmpzr1t_l9r_go_relaxed.owl	RSP5-BUL1 complex|RSP5-BUL2 complex					This complex has been identified in Saccharomyces cerevisiae (P19812) - see PMID:9931424		bhm	2014-03-03T22:53:01Z					cellular_component											owl:Class	
GO:0052794	biolink:NamedThing	exo-alpha-(2->3)-sialidase activity	Catalysis of the hydrolysis of alpha-(2->3)-glycosidic linkages of terminal sialic residues in substrates.	tmpzr1t_l9r_go_relaxed.owl	exo-alpha-2,3-sialidase activity|exo-alpha-(2,3)-sialidase activity				EC:3.2.1.18									molecular_function											owl:Class	
GO:0019185	biolink:NamedThing	snRNA-activating protein complex	A protein complex that recognizes the proximal sequence element of RNA polymerase II and III snRNA promoters.	tmpzr1t_l9r_go_relaxed.owl	SNAPc													cellular_component											owl:Class	
GO:0090436	biolink:NamedThing	leaf pavement cell development	The process whose specific outcome is the progression of an leaf pavement cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a leaf pavement cell fate.	tmpzr1t_l9r_go_relaxed.owl								tb	2012-07-31T16:08:53Z					biological_process											owl:Class	
GO:0047756	biolink:NamedThing	chondroitin 4-sulfotransferase activity	Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + chondroitin = adenosine 3',5'-bisphosphate + chondroitin 4'-sulfate.	tmpzr1t_l9r_go_relaxed.owl	3'-phosphoadenylyl-sulfate:chondroitin 4'-sulfotransferase activity|chondroitin 4-sulphotransferase activity				EC:2.8.2.5|Reactome:R-HSA-1971483|RHEA:16101|MetaCyc:CHONDROITIN-4-SULFOTRANSFERASE-RXN									molecular_function											owl:Class	
GO:0047565	biolink:NamedThing	3-hydroxypropionate dehydrogenase (NAD+) activity	Catalysis of the reaction: 3-hydroxypropanoate + NAD(+) = 3-oxopropanoate + H(+) + NADH.	tmpzr1t_l9r_go_relaxed.owl	3-hydroxypropanoate:NAD+ oxidoreductase activity				MetaCyc:3-HYDROXYPROPIONATE-DEHYDROGENASE-RXN|EC:1.1.1.59|RHEA:13357|KEGG_REACTION:R01608									molecular_function											owl:Class	
GO:0140069	biolink:NamedThing	histone butyryltransferase activity	Catalysis of the reaction: butyryl-CoA + histone = CoA + butyryl-histone.	tmpzr1t_l9r_go_relaxed.owl								pg	2017-07-20T16:56:33Z					molecular_function											owl:Class	
GO:0034678	biolink:NamedThing	integrin alpha8-beta1 complex	An integrin complex that comprises one alpha8 subunit and one beta1 subunit.	tmpzr1t_l9r_go_relaxed.owl	alpha8-beta1 integrin complex|ITGA8-ITGB1 complex													cellular_component											owl:Class	
GO:1990342	biolink:NamedThing	heterochromatin island	A region of facultative heterochromatin formed dynamically at specific loci in response to environmental signals, independently of RNAi.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/11247				An example of this type of heterochromatin is found in Schizosaccharomyces pombe, where heterochromatin islands are formed at meiotic genes during vegetative (mitotic) growth.		mah	2014-03-21T15:26:44Z					cellular_component											owl:Class	
GO:0042183	biolink:NamedThing	formate catabolic process	The chemical reactions and pathways resulting in the breakdown of formate, also known as methanoate, the anion HCOO- derived from methanoic (formic) acid.	tmpzr1t_l9r_go_relaxed.owl	formate catabolism|formic acid catabolism|formic acid catabolic process|formate breakdown|formate degradation													biological_process											owl:Class	
GO:0006229	biolink:NamedThing	dUTP biosynthetic process	The chemical reactions and pathways resulting in the formation of dUTP, deoxyuridine (5'-)triphosphate.	tmpzr1t_l9r_go_relaxed.owl	dUTP formation|dUTP biosynthesis|dUTP anabolism|dUTP synthesis													biological_process											owl:Class	
GO:0071199	biolink:NamedThing	Kv4.1-DPP10 channel complex	A voltage-gated potassium channel complex that contains the peptidase-related protein DPP10 associated with the channel via interaction with the Kv alpha subunit 4.1.	tmpzr1t_l9r_go_relaxed.owl	Kv4.1-DPPY channel complex				CORUM:601			mah	2009-11-23T05:17:50Z					cellular_component											owl:Class	
GO:0036235	biolink:NamedThing	acyl deglucuronidation	The removal of glucuronic acid from an acyl-glucuronide.	tmpzr1t_l9r_go_relaxed.owl								bf	2012-05-18T04:24:11Z					biological_process											owl:Class	
GO:0036234	biolink:NamedThing	deglucuronidation	The removal of glucuronic acid from a conjugated substrate.	tmpzr1t_l9r_go_relaxed.owl								bf	2012-05-18T04:23:04Z					biological_process											owl:Class	
GO:0018723	biolink:NamedThing	3-phenanthrol sulfotransferase activity	Catalysis of the reaction: 3-phenanthrol + X-SO3(-) = HX + 3-phenanthrylsulfate.	tmpzr1t_l9r_go_relaxed.owl	3-phenanthrol sulphotransferase activity				UM-BBD_reactionID:r0561									molecular_function											owl:Class	
GO:0033720	biolink:NamedThing	(S)-mandelate dehydrogenase activity	Catalysis of the reaction: (S)-2-hydroxy-2-phenylacetate + acceptor = 2-oxo-2-phenylacetate + reduced acceptor.	tmpzr1t_l9r_go_relaxed.owl	MDH|(S)-2-hydroxy-2-phenylacetate:acceptor 2-oxidoreductase activity|L(+)-mandelate dehydrogenase activity				EC:1.1.99.31|RHEA:15749|MetaCyc:MANDELATE-DEHYDROGENASE-RXN|UM-BBD_reactionID:r1048|MetaCyc:MANDELATE-OXY-RXN									molecular_function											owl:Class	
GO:0061205	biolink:NamedThing	paramesonephric duct development	The process whose specific outcome is the progression of the paramesonephric duct over time, from its formation to the mature structure. Mullerian ducts (or paramesonephric ducts) are paired ducts of the embryo that run down the lateral sides of the urogenital ridge and terminate at the mullerian eminence in the primitive urogenital sinus. In the female, they will develop to form the fallopian tubes, uterus, cervix, and the upper portion of the vagina; in the male, they are lost. These ducts are made of tissue of mesodermal origin.	tmpzr1t_l9r_go_relaxed.owl	Mullerian duct development							dph	2010-07-30T10:54:47Z					biological_process											owl:Class	
GO:0102202	biolink:NamedThing	soladodine glucosyltransferase activity	Catalysis of the reaction: UDP-alpha-D-glucose + solasodine <=> UDP + solasodine 3-O-beta-D-glucopyranoside + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-12123|RHEA:61844|EC:2.4.1.173									molecular_function											owl:Class	
GO:0016443	biolink:NamedThing	bidentate ribonuclease III activity	Catalysis of the digestion of double-stranded RNAs into 20 to 30-nucleotide products. These products typically associate to the RNA-induced silencing complex and serve as guide RNAs for posttranslational RNA interference.	tmpzr1t_l9r_go_relaxed.owl	bidentate RNase III activity				EC:3.1.26.-									molecular_function											owl:Class	
GO:0019920	biolink:NamedThing	peptidyl-1-thioglycine biosynthetic process, internal	The chemical reactions and pathways resulting in the formation of internal peptidyl-1-thioglycine, which has an internal C=S bond, instead of an internal C=O bond, in the peptide.	tmpzr1t_l9r_go_relaxed.owl	peptidyl-1-thioglycine anabolism, internal|peptidyl-1-thioglycine formation, internal|peptidyl-1-thioglycine synthesis, internal				RESID:AA0265									biological_process											owl:Class	
GO:0102842	biolink:NamedThing	1-18:1-2-16:2-monogalactosyldiacylglycerol desaturase activity (SN2-16:3 forming)	Catalysis of the reaction: 1-18:1-2-16:2-monogalactosyldiacylglycerol + O2 + a reduced electron acceptor = 1-18:1-2-16:3-monogalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-8303|EC:1.14.19.35|RHEA:46412									molecular_function											owl:Class	
GO:0050055	biolink:NamedThing	limonin-D-ring-lactonase activity	Catalysis of the reaction: limonoate D-ring-lactone + H2O = limonoate.	tmpzr1t_l9r_go_relaxed.owl	limonin lactone hydrolase activity|limonoate-D-ring-lactone lactonohydrolase activity|limonin-D-ring-lactone hydrolase activity				EC:3.1.1.36|MetaCyc:LIMONIN-D-RING-LACTONASE-RXN|RHEA:10896									molecular_function											owl:Class	
GO:0050229	biolink:NamedThing	pterocarpin synthase activity	Catalysis of the reaction: medicarpin + NADP+ = vestitone + NADPH.	tmpzr1t_l9r_go_relaxed.owl	pterocarpan synthase activity|medicarpin:NADP+ 2'-oxidoreductase activity				MetaCyc:PTEROCARPIN-SYNTHASE-RXN|RHEA:13533|EC:1.1.1.246									molecular_function											owl:Class	
GO:0003976	biolink:NamedThing	UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity	Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + lysosomal-enzyme D-mannose = UMP + lysosomal-enzyme N-acetyl-D-glucosaminyl-phospho-D-mannose.	tmpzr1t_l9r_go_relaxed.owl	N-acetylglucosaminyl phosphotransferase activity|lysosomal enzyme precursor acetylglucosamine-1-phosphotransferase activity|UDP-N-acetylglucosamine:glycoprotein N-acetylglucosaminyl-1-phosphotransferase activity|UDP-GlcNAc:glycoprotein N-acetylglucosamine-1-phosphotransferase activity|UDP-N-acetyl-D-glucosamine:lysosomal-enzyme N-acetylglucosaminephosphotransferase activity|N-acetylglucosaminylphosphotransferase activity|UDP-N-acetylglucosamine:glycoprotein N-acetylglucosamine-1-phosphotransferase activity|UDP-N-acetylglucosamine:lysosomal enzyme N-acetylglucosamine-1-phosphotransferase activity				MetaCyc:2.7.8.17-RXN|EC:2.7.8.17|RHEA:13581									molecular_function											owl:Class	
GO:0045232	biolink:NamedThing	S-layer organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an S-layer enveloping the cell. The S-layer is a crystalline protein layer surrounding some bacteria.	tmpzr1t_l9r_go_relaxed.owl	S-layer organisation|S-layer organization and biogenesis													biological_process											owl:Class	
GO:0051506	biolink:NamedThing	ergosterol UDP-glucosyltransferase activity	Catalysis of the reaction: UDP-glucose + ergosterol = UDP + O-glucosyl-ergosterol.	tmpzr1t_l9r_go_relaxed.owl					RHEA:61836|MetaCyc:RXN-16975)									molecular_function											owl:Class	
GO:0043540	biolink:NamedThing	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex	A homodimeric, bifunctional enzyme complex which catalyzes the synthesis and degradation of fructose 2,6-bisphosphate, and is required for both glycolysis and gluconeogenesis.	tmpzr1t_l9r_go_relaxed.owl	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 complex|6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 complex|6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 complex|6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 complex					Note that we use this single class to represent all 4 isoforms of this complex. We decided to do this because the isoforms do not differ in function, rather in expression and regulation. We may want to revisit this in future.								cellular_component											owl:Class	
GO:0043739	biolink:NamedThing	G/U mismatch-specific uracil-DNA glycosylase activity	Catalysis of the removal of uracil from a U*G mispair by the cleavage the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar. The reaction releases a free uracil and leaves an apyrimidinic (AP) site.	tmpzr1t_l9r_go_relaxed.owl	GU mismatch-specific uracil-DNA glycosylase activity|MUG|uracil mismatch repair protein													molecular_function											owl:Class	
GO:0030781	biolink:NamedThing	6-O-methylnorlaudanosoline 5'-O-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + 6-O-methylnorlaudanosoline = S-adenosyl-L-homocysteine + nororientaline.	tmpzr1t_l9r_go_relaxed.owl	S-adenosyl-L-methionine:6-O-methylnorlaudanosoline 5'-O-methyltransferase activity				MetaCyc:2.1.1.121-RXN|EC:2.1.1.121|RHEA:11892									molecular_function											owl:Class	
GO:0047361	biolink:NamedThing	phosphomannan mannosephosphotransferase activity	Catalysis of the reaction: phosphomannan(n) + GDP-mannose = phosphomannan(n+1) + GMP.	tmpzr1t_l9r_go_relaxed.owl	GDP-mannose:phosphomannan mannose phosphotransferase activity				EC:2.7.8.9|MetaCyc:2.7.8.9-RXN									molecular_function											owl:Class	
GO:0070312	biolink:NamedThing	RAD52-ERCC4-ERCC1 complex	A nucleotide-excision repair complex formed by the association of the heterodimeric endonuclease XPF/ERCC4-ERCC1 (Rad1p and Rad10p in S. cerevisiae) with the RAD52 protein.	tmpzr1t_l9r_go_relaxed.owl						Note that process and function information are included in the term and definition for the purpose of describing and distinguishing the complex.								cellular_component											owl:Class	
GO:0097655	biolink:NamedThing	serpin family protein binding	Binding to a member of the serpin protein family (serine protease inhibitors or classified inhibitor family I4). Serpins are a broadly distributed family of protease inhibitors that use a conformational change to inhibit target enzymes. They are central in controlling many important proteolytic cascades. The majority of serpins inhibit serine proteases, but serpins that inhibit caspases and papain-like cysteine proteases have also been identified. Rarely, serpins perform a non-inhibitory function; for example, several human serpins function as hormone transporters and certain serpins function as molecular chaperones or tumor suppressors.	tmpzr1t_l9r_go_relaxed.owl								pr	2014-09-24T16:19:31Z					molecular_function											owl:Class	
GO:0004423	biolink:NamedThing	iduronate-2-sulfatase activity	Catalysis of the hydrolysis of the 2-sulfate groups of the L-iduronate 2-sulfate units of dermatan sulfate, heparan sulfate and heparin.	tmpzr1t_l9r_go_relaxed.owl	idurono-2-sulfatase activity|iduronate sulfate sulfatase activity|L-iduronate 2-sulfate sulfatase activity|iduronate sulfatase activity|sulfo-L-iduronate sulfatase activity|2-sulfo-L-iduronate 2-sulfatase activity|L-iduronate-2-sulfate 2-sulfohydrolase activity|L-iduronosulfatase activity|iduronide-2-sulfate sulfatase activity|chondroitinsulfatase|L-idurono sulfate sulfatase activity|iduronate-2-sulphatase activity|iduronate-2-sulfate sulfatase activity|sulfoiduronate sulfohydrolase activity				Reactome:R-HSA-1793182|Reactome:R-HSA-2262743|Reactome:R-HSA-9036046|Reactome:R-HSA-1678650|EC:3.1.6.13|MetaCyc:3.1.6.13-RXN									molecular_function											owl:Class	
GO:0008923	biolink:NamedThing	lysine decarboxylase activity	Catalysis of the reaction: L-lysine + H(+) = cadaverine + CO(2).	tmpzr1t_l9r_go_relaxed.owl	L-lysine carboxy-lyase activity|L-lysine carboxy-lyase (cadaverine-forming)				MetaCyc:PWY0-461|EC:4.1.1.18|RHEA:22352|KEGG_REACTION:R00462|MetaCyc:LYSDECARBOX-RXN									molecular_function											owl:Class	
GO:1990450	biolink:NamedThing	linear polyubiquitin binding	Binding to a linear polymer of ubiquitin. Linear ubiquitin polymers are formed by linking the amino-terminal methionine (M1) of one ubiquitin molecule to the carboxy-terminal glycine (G76) of the next.	tmpzr1t_l9r_go_relaxed.owl	M1-linked ubiquitin chain binding							bf	2014-08-06T11:10:26Z					molecular_function											owl:Class	
GO:0043130	biolink:NamedThing	ubiquitin binding	Binding to ubiquitin, a protein that when covalently bound to other cellular proteins marks them for proteolytic degradation.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-205008|Reactome:R-HSA-983152|Reactome:R-HSA-1169404									molecular_function											owl:Class	
GO:0032705	biolink:NamedThing	negative regulation of interleukin-21 production	Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-21 production.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of interleukin-21 production|down regulation of interleukin-21 production|downregulation of interleukin-21 production|negative regulation of interleukin-21 biosynthetic process											GO:0045391		biological_process											owl:Class	
GO:0019652	biolink:NamedThing	lactate fermentation to propionate and acetate	The anaerobic enzymatic conversion of lactate to propionate, concomitant with the oxidation of lactate to acetate and CO2 and yielding energy in the form of adenosine triphosphate (ATP).	tmpzr1t_l9r_go_relaxed.owl	nonrandomizing pathway|acrylate pathway|propionate fermentation				MetaCyc:PROPFERM-PWY									biological_process											owl:Class	
GO:0004502	biolink:NamedThing	kynurenine 3-monooxygenase activity	Catalysis of the reaction: L-kynurenine + H(+) + NADPH + O(2) = 3-hydroxy-L-kynurenine + H(2)O + NADP(+).	tmpzr1t_l9r_go_relaxed.owl	L-kynurenine,NADPH:oxygen oxidoreductase (3-hydroxylating)|L-kynurenine-3-hydroxylase activity|kynurenine 3-hydroxylase activity|kynurenine hydroxylase activity				Reactome:R-HSA-71200|RHEA:20545|MetaCyc:KYNURENINE-3-MONOOXYGENASE-RXN|KEGG_REACTION:R01960|EC:1.14.13.9									molecular_function											owl:Class	
GO:0007192	biolink:NamedThing	adenylate cyclase-activating serotonin receptor signaling pathway	The series of molecular signals generated as a consequence of a serotonin receptor binding to its physiological ligand, where the pathway proceeds with activation of adenylyl cyclase and a subsequent increase in the concentration of cyclic AMP (cAMP).	tmpzr1t_l9r_go_relaxed.owl	serotonin receptor, adenylyl cyclase activating pathway|activation of adenylate cyclase activity by serotonin receptor signalling pathway|serotonin receptor, adenylate cyclase activating pathway													biological_process											owl:Class	
GO:0000701	biolink:NamedThing	purine-specific mismatch base pair DNA N-glycosylase activity	Catalysis of the removal of purines present in mismatches, especially opposite oxidized purines, by cleaving the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar. The reaction releases a free base and leaves an apurinic (AP) site.	tmpzr1t_l9r_go_relaxed.owl	A/G-specific adenine DNA glycosylase activity				EC:3.2.2.31									molecular_function											owl:Class	
GO:0070033	biolink:NamedThing	synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex	A SNARE complex that contains synaptobrevin 2 (VAMP2), SNAP-25, syntaxin 1a, and complexin II (or orthologs thereof).	tmpzr1t_l9r_go_relaxed.owl	Vamp2-Snap25-Stx1a-Cplx2 complex|SNARE complex (Vamp2, Snap25, Stx1a, Cplx2)													cellular_component											owl:Class	
GO:0034577	biolink:NamedThing	N-isopropylacetaniline monooxygenase activity	Catalysis of the reaction: N-isopropylacetanilide + 1/2 O2 = acetanilide + acetone.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0914|EC:1.14.15.-									molecular_function											owl:Class	
GO:0102358	biolink:NamedThing	daphnetin-8-O-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine  + 7,8-dihydroxycoumarin <=> S-adenosyl-L-homocysteine  + 7-hydroxy-8-methoxycoumarin + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-13448									molecular_function											owl:Class	
GO:0009905	biolink:NamedThing	ent-copalyl diphosphate synthase activity	Catalysis of the reaction: all-trans-geranylgeranyl diphosphate = ent-copalyl diphosphate.	tmpzr1t_l9r_go_relaxed.owl	ent-kaurene synthetase A activity|ent-copalyl-diphosphate lyase (decyclizing)|ent-kaurene synthase A activity|diterpene cyclase activity				KEGG_REACTION:R02068|RHEA:14841|EC:5.5.1.13|MetaCyc:5.5.1.13-RXN									molecular_function											owl:Class	
GO:0045047	biolink:NamedThing	protein targeting to ER	The process of directing proteins towards the endoplasmic reticulum (ER) using signals contained within the protein. One common mechanism uses a 16- to 30-residue signal sequence, typically located at the N-terminus of the protein and containing positively charged amino acids followed by a continuous stretch of hydrophobic residues, which directs the ribosome to the ER membrane and initiates transport of the growing polypeptide across the ER membrane.	tmpzr1t_l9r_go_relaxed.owl	protein targeting to endoplasmic reticulum|protein-endoplasmic reticulum targeting|protein-ER targeting													biological_process											owl:Class	
GO:0009762	biolink:NamedThing	NADP-malic enzyme C4 photosynthesis	The process of C4 photosynthesis, as it occurs in plants in which the enzyme decarboxylating C4 acids in the bundle sheath is NADP-malic enzyme.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:PWY-241									biological_process											owl:Class	
GO:0102333	biolink:NamedThing	stearoyl-[acp] elongase/decarboxylase activity	Catalysis of the reaction: malonyl-CoA + 3 H+ + a stearoyl-[acp] = nonadec-1-ene + 2 carbon dioxide + coenzyme A + a holo-[acyl-carrier protein].	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-13261									molecular_function											owl:Class	
GO:0101029	biolink:NamedThing	negative regulation of liquid surface tension	Any process that prevents or reduces the surface tension of a liquid.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of surface tension of a liquid													biological_process											owl:Class	
GO:0030907	biolink:NamedThing	MBF transcription complex	A protein complex that binds to the Mlu1 cell cycle box (MCB) promoter element, consensus sequence ACGCGN, and is involved in regulation of transcription during the G1/S transition of the cell cycle. In Saccharomyces, the complex contains a heterodimer of the DNA binding protein Mbp1p and the activator Swi6p, and is associated with additional proteins known as Nrm1p, Msa1p, and Msa2p; in Schizosaccharomyces the complex contains Res1p, Res2p, and Cdc10p.	tmpzr1t_l9r_go_relaxed.owl	Mlu1-box binding factor|DSC1 transcription factor complex|MBF													cellular_component											owl:Class	
GO:0031516	biolink:NamedThing	far-red light photoreceptor activity	The function of absorbing and responding to electromagnetic radiation with a wavelength of approximately 730nm. The response may involve a change in conformation.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0018854	biolink:NamedThing	3-isopropenyl-6-oxoheptanoyl-CoA synthetase activity	Catalysis of the reaction: (3R)-3-isopropenyl-6-oxoheptanoate + CoA-SH + ATP = H2O + ADP/AMP + mono/diphosphate + (3R)-3-isopropenyl-6-oxoheptanoyl-CoA.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0737									molecular_function											owl:Class	
GO:0103071	biolink:NamedThing	2-hydroxy-3-methyl-branched 2,3,4-saturated fatty acyl-CoA lyase activity	Catalysis of the reaction: a 2-hydroxy-3-methyl-branched 2,3,4-saturated fatty acyl-CoA <=> formyl-CoA + a 2-methyl branched 2,3,4-saturated fatty aldehyde.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN66-471									molecular_function											owl:Class	
GO:0009027	biolink:NamedThing	tartrate dehydrogenase activity	Catalysis of the reaction: tartrate + NAD+ = oxaloglycolate + NADH + H+.	tmpzr1t_l9r_go_relaxed.owl	tartrate:NAD+ oxidoreductase activity|mesotartrate dehydrogenase activity				MetaCyc:TARTRATE-DEHYDROGENASE-RXN|EC:1.1.1.93|RHEA:15209									molecular_function											owl:Class	
GO:0047399	biolink:NamedThing	glucose-1-phospho-D-mannosylglycoprotein phosphodiesterase activity	Catalysis of the reaction: H2O + 6-(D-glucose-1-phospho)-D-mannosylglycoprotein = D-mannosylglycoprotein + D-glucose-alpha-1-phosphate.	tmpzr1t_l9r_go_relaxed.owl	alpha-glucose-1-phosphate phosphodiesterase activity|6-(D-glucose-1-phospho)-D-mannosylglycoprotein glucose-1-phosphohydrolase activity				MetaCyc:3.1.4.51-RXN|EC:3.1.4.51|RHEA:18045									molecular_function											owl:Class	
GO:2001082	biolink:NamedThing	inulin binding	Binding to inulin.	tmpzr1t_l9r_go_relaxed.owl								jl	2011-09-15T01:23:59Z					molecular_function											owl:Class	
GO:0035576	biolink:NamedThing	retinoic acid receptor signaling pathway involved in pronephric field specification	The series of molecular signals generated as a consequence of a retinoic acid receptor binding to one of its physiological ligands that results in regions of the embryo being delineated into the area in which the pronephric kidney will develop.	tmpzr1t_l9r_go_relaxed.owl	retinoic acid receptor signalling pathway involved in pronephric field specification							bf	2010-10-05T01:19:35Z					biological_process											owl:Class	
GO:0014843	biolink:NamedThing	growth factor dependent regulation of skeletal muscle satellite cell proliferation	Any process that modulates the frequency, rate or extent of satellite cell proliferation; dependent on specific growth factor activity such as fibroblast growth factors and transforming growth factor beta.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0097609	biolink:NamedThing	longitudinal flagellum	A motile cilium found in dinoflagellates. It trails the cell and acts as a steering rudder. It is often partially contained in a furrow called the sulcus, and emerges from a flagellar pore located in the sulcus.	tmpzr1t_l9r_go_relaxed.owl	longitudinal cilium					Note that we deem cilium and microtubule-based flagellum to be equivalent. In this case community usage refers to 'flagellum' rather than 'cilium', hence the primary term name, but the cilium parentage is deliberate.		pr	2014-06-09T11:21:10Z					cellular_component											owl:Class	
GO:0052917	biolink:NamedThing	dolichyl-P-Man:Man(7)GlcNAc(2)-PP-dolichol alpha-1,6-mannosyltransferase	Catalysis of the addition of mannose to dolichyl-pyrophosphate Man7GlcNAc2 (also written as Man7GlcNAc2-PP-Dol) in alpha-(1->6) linkage, producing Man8GlcNAc2-PP-Dol.	tmpzr1t_l9r_go_relaxed.owl	dolichyl-P-mannose:Man(7)GlcNAc(2)-PP-dolichyl mannosyltransferase activity|dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase activity|dolichyl-pyrophosphate Man7GlcNAc2 alpha-1,6-mannosyltransferase activity	https://github.com/geneontology/go-ontology/issues/19075			EC:2.4.1.260|MetaCyc:RXN-5468|RHEA:29535|KEGG_REACTION:R06260							GO:0052824		molecular_function											owl:Class	
GO:0035123	biolink:NamedThing	embryonic dorsal fin morphogenesis	The process, occurring in the embryo, by which the anatomical structures of the dorsal fin are generated and organized. A dorsal fin is an unpaired medial fin on the dorsal aspect of a fish that provides lateral stability while swimming. Generally fish have one or two dorsal fins.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0048014	biolink:NamedThing	Tie signaling pathway	The series of molecular signals generated as a consequence of a Tie protein (a receptor) binding to one of its physiological ligands (an angiopoietin).	tmpzr1t_l9r_go_relaxed.owl	Tek receptor signaling|Tie receptor signaling pathway|angiopoietin-Tie signaling pathway|Tie receptor signalling pathway|angiopoietin/Tie signaling pathway													biological_process											owl:Class	
GO:0070465	biolink:NamedThing	alpha1-beta1 integrin-alpha3(VI) complex	A protein complex that consists of an alpha1-beta1 integrin complex bound to a type VI collagen triple helix containing an alpha3(VI) chain.	tmpzr1t_l9r_go_relaxed.owl	ITGA1-ITGB1-COL6A3 complex													cellular_component											owl:Class	
GO:0102894	biolink:NamedThing	UDPG:cyclo-DOPA 5-O-glucosyltransferase activity	Catalysis of the reaction: UDP-alpha-D-glucose + leucodopachrome <=> H+ + cyclo-dopa 5-O-glucoside + UDP.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-8481									molecular_function											owl:Class	
GO:0055053	biolink:NamedThing	mannose:proton symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: mannose + H+ = mannose + H+.	tmpzr1t_l9r_go_relaxed.owl	mannose:hydrogen symporter activity													molecular_function											owl:Class	
GO:0052731	biolink:NamedThing	phosphocholine phosphatase activity	Catalysis of the reaction: choline phosphate + H2O = choline + phosphate.	tmpzr1t_l9r_go_relaxed.owl	PHOSPHO1|3X11A|phosphoethanolamine phosphohydrolase activity				Reactome:R-HSA-1483159|KEGG_REACTION:R06871|MetaCyc:RXN-5647|RHEA:10492|EC:3.1.3.75			ai	2011-08-16T04:09:06Z					molecular_function											owl:Class	
GO:0019484	biolink:NamedThing	beta-alanine catabolic process	The chemical reactions and pathways resulting in the breakdown of beta-alanine (3-aminopropanoic acid), an achiral amino acid and an isomer of alanine. It occurs free (e.g. in brain) and in combination (e.g. in pantothenate) but it is not a constituent of proteins.	tmpzr1t_l9r_go_relaxed.owl	beta-alanine breakdown|beta-alanine catabolism|beta-alanine degradation													biological_process											owl:Class	
GO:0035274	biolink:NamedThing	diphenyl phthalate binding	Binding to diphenyl phthalate, C(20)H(14)O(4).	tmpzr1t_l9r_go_relaxed.owl	DPP binding													molecular_function											owl:Class	
GO:0034630	biolink:NamedThing	RITS complex localization	Any process in which a RITS complex is transported to, or maintained in, a specific location.	tmpzr1t_l9r_go_relaxed.owl	RITS complex localisation|establishment and maintenance of RITS complex localization													biological_process											owl:Class	
GO:0098648	biolink:NamedThing	collagen anchoring fibril	A specialised collagen fibril that functions as an anchor, binding to other collagen structures.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0031828	biolink:NamedThing	type 2C serotonin receptor binding	Binding to a type 2C serotonin receptor.	tmpzr1t_l9r_go_relaxed.owl	type 2C serotonin receptor ligand|5-hydroxytryptamine 2C receptor binding													molecular_function											owl:Class	
GO:0005597	biolink:NamedThing	collagen type XVI trimer	A collagen trimer containing alpha(XVI) chains; type XVI trimers can associate with microfibrils.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0010526	biolink:NamedThing	negative regulation of transposition, RNA-mediated	Any process that decreases the frequency, rate or extent of RNA-mediated transposition. RNA-mediated transposition is a type of transpositional recombination which occurs via an RNA intermediate.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0099045	biolink:NamedThing	viral extrusion	The process whereby a filamentous phage particle is released from a bacterial host cell via a concerted mechanism of assembly and secretion. Neosynthesized virions are coordinately exported as they are assembled at the cell surface in a secretory process that leaves the host cell fully viable.  Non-capsid proteins form structures that facilitate translocation through the inner membrane and outer membranes. A viral single-stranded DNA binding protein coats progeny viral DNA molecules to generate the intracellular precursor for assembly of phage particles as they are extruded through the membranes of the bacterial host. The structural proteins of the virus are anchored in the inner membrane before their incorporation into the phage particle. As assembly proceeds, the phage genome traverses the inner and outer membranes until the entire DNA molecule has been coated and extruded.	tmpzr1t_l9r_go_relaxed.owl					VZ:3951									biological_process											owl:Class	
GO:0001531	biolink:NamedThing	interleukin-21 receptor binding	Binding to an interleukin-21 receptor.	tmpzr1t_l9r_go_relaxed.owl	IL-21|interleukin-21 receptor ligand													molecular_function											owl:Class	
GO:0070079	biolink:NamedThing	histone H4-R3 demethylation	The modification of histone H4 by the removal of a methyl group from arginine at position 3 of the histone.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0018768	biolink:NamedThing	2-hydroxy-6-oxo-6-(2'-aminophenyl)hexa-2,4-dienoate hydrolase activity	Catalysis of the reaction: 2-hydroxy-6-oxo-(2'-aminophenyl)-hexa-2,4-dienoate + H2O = 2-aminobenzoate + cis-2-hydroxypenta-2,4-dienoate.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0458|EC:3.7.1.13									molecular_function											owl:Class	
GO:0106034	biolink:NamedThing	protein maturation by [2Fe-2S] cluster transfer	The transfer of an assembled [2Fe-2S] cluster from a scaffold protein to an acceptor protein that contributes to the attainment of the full functional capacity of a protein.	tmpzr1t_l9r_go_relaxed.owl								hjd	2017-07-07T17:24:59Z					biological_process											owl:Class	
GO:1905040	biolink:NamedThing	otic placode development	The process whose specific outcome is the progression of an otic placode over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl	octaval placode development|auditory placode development|ear placode development|placoda otica development|octaval VIII placode development|ear/otic placode development							bf	2016-03-10T09:30:20Z					biological_process											owl:Class	
GO:0140413	biolink:NamedThing	zinc:bicarbonate:selenite symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: zinc(out) + HCO3-(out) + HO3Se-(out) = zinc(in) + HCO3-(in) + HO3Se-(out).	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/18345						pg	2020-01-07T18:58:12Z					molecular_function											owl:Class	
GO:0106342	biolink:NamedThing	omega-hydroxyceramide biosynthetic process	The chemical reactions and pathways resulting in the formation of omega-hydroxyceramide/acylceramide.	tmpzr1t_l9r_go_relaxed.owl								hjd	2020-11-17T17:15:25Z					biological_process											owl:Class	
GO:0034236	biolink:NamedThing	protein kinase A catalytic subunit binding	Binding to one or both of the catalytic subunits of protein kinase A.	tmpzr1t_l9r_go_relaxed.owl	PKA catalytic subunit binding													molecular_function											owl:Class	
GO:0036359	biolink:NamedThing	renal potassium excretion	The elimination by an organism of potassium in the urine.	tmpzr1t_l9r_go_relaxed.owl	renal K(+) excretion|renal K+ elimination|renal potassium ion excretion							bf	2012-09-20T11:10:47Z					biological_process											owl:Class	
GO:0014882	biolink:NamedThing	regulation of myofibril number	Any process that modulates the number of myofibrils. A myofibril is the contractile element of skeletal and cardiac muscle. It is a long, highly organized bundle of actin, myosin, and other proteins that contracts by a sliding filament mechanism.	tmpzr1t_l9r_go_relaxed.owl	change of myofibril number													biological_process											owl:Class	
GO:0032427	biolink:NamedThing	GBD domain binding	Binding to a GTPase protein binding domain (GDB) domain. The GBD is a short motif, including a minimum region of 16 amino acids, identified in proteins that bind to small GTPases such as Cdc42 and Rac.	tmpzr1t_l9r_go_relaxed.owl	Cdc42/Rac interactive binding motif binding|P21-Rho-binding domain binding|PMD binding|CRIB motif binding													molecular_function											owl:Class	
GO:0046816	biolink:NamedThing	virion transport vesicle	A vesicle used to transport the partial or complete virion between cellular compartments.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0042187	biolink:NamedThing	p-xylene catabolic process	The chemical reactions and pathways resulting in the breakdown of p-xylene (1,4-dimethylbenzene), a colorless, liquid aromatic hydrocarbon.	tmpzr1t_l9r_go_relaxed.owl	p-xylene catabolism|para-xylene catabolism|p-xylene degradation|para-xylene catabolic process|p-xylene breakdown													biological_process											owl:Class	
GO:0018951	biolink:NamedThing	p-xylene metabolic process	The chemical reactions and pathways involving p-xylene, (1,4-dimethylbenzene) a colorless, liquid aromatic hydrocarbon.	tmpzr1t_l9r_go_relaxed.owl	para-xylene metabolism|p-xylene metabolism|para-xylene metabolic process				UM-BBD_pathwayID:pxy									biological_process											owl:Class	
GO:0061033	biolink:NamedThing	secretion by lung epithelial cell involved in lung growth	The controlled release of liquid by a lung epithelial cell that contributes to an increase in size of the lung as part of its development.	tmpzr1t_l9r_go_relaxed.owl	fetal lung liquid secretion							dph	2010-02-09T10:02:55Z					biological_process											owl:Class	
GO:1990145	biolink:NamedThing	maintenance of translational fidelity	Suppression of the occurrence of translational errors, such as codon-anticodon mis-paring, during the process of translation of a protein using an mRNA template.	tmpzr1t_l9r_go_relaxed.owl								hjd	2013-07-24T19:30:09Z					biological_process											owl:Class	
GO:0045129	biolink:NamedThing	NAD-independent histone deacetylase activity	Catalysis of the reaction: histone N6-acetyl-L-lysine + H2O = histone L-lysine + acetate. This reaction does not require the presence of NAD, and represents the removal of an acetyl group from a histone.	tmpzr1t_l9r_go_relaxed.owl	AcuC													molecular_function											owl:Class	
GO:0070515	biolink:NamedThing	alphaIIb-beta3 integrin-talin complex	A protein complex that consists of an alphaIIb-beta3 integrin complex bound to talin.	tmpzr1t_l9r_go_relaxed.owl	ITGA2b-ITGB3-TLN1 complex													cellular_component											owl:Class	
GO:0042715	biolink:NamedThing	dosage compensation complex assembly involved in dosage compensation by hypoactivation of X chromosome	The aggregation, arrangement and bonding together of proteins on DNA to form the complex that mediates dosage compensation on both X chromosomes in the monogametic sex, ultimately resulting in a two-fold reduction in transcription from these chromosomes. An example of this process is found in Caenorhabditis elegans.	tmpzr1t_l9r_go_relaxed.owl	dosage compensation complex assembly during dosage compensation by hypoactivation of X chromosome													biological_process											owl:Class	
GO:0061935	biolink:NamedThing	fusion of sperm to egg plasma membrane involved in double fertilization forming two zygotes	The binding and fusion of a sperm, with the plasma membrane of the oocyte as part of the process of double fertilization forming two zygotes.	tmpzr1t_l9r_go_relaxed.owl								dph	2017-09-05T18:38:08Z					biological_process											owl:Class	
GO:0033888	biolink:NamedThing	chondro-6-sulfatase activity	Catalysis of the reaction: 4-deoxy-beta-D-gluc-4-enuronosyl-(1->3)-N-acetyl-D-galactosamine 6-sulfate + H(2)O = 4-deoxy-beta-D-gluc-4-enuronosyl-(1->3)-N-acetyl-D-galactosamine + H(+) + sulfate.	tmpzr1t_l9r_go_relaxed.owl	4-deoxy-beta-D-gluc-4-enuronosyl-(1,3)-N-acetyl-D-galactosamine-6-sulfate 6-sulfohydrolase activity				EC:3.1.6.10|KEGG_REACTION:R03518|MetaCyc:CHONDRO-6-SULFATASE-RXN|RHEA:10536									molecular_function											owl:Class	
GO:0071153	biolink:NamedThing	G-protein alpha(o)-synembrin complex	A protein complex formed by the association of the guanine nucleotide exchange factor synembrin with the alpha(o) subunit of a heterotrimeric G protein.	tmpzr1t_l9r_go_relaxed.owl	Ric-8A G(o) alpha-1 subunit complex|Ric-8A G(o) alpha-2 subunit complex							mah	2009-11-16T04:55:00Z					cellular_component											owl:Class	
GO:0033960	biolink:NamedThing	N-methyl nucleosidase activity	Catalysis of the reaction: 7-methylxanthosine + H(2)O = 7-methylxanthine + H(+) + ribofuranose.	tmpzr1t_l9r_go_relaxed.owl	N-methyl nucleoside hydrolase activity|methylpurine nucleosidase activity|7-methylxanthosine nucleosidase activity|N-MeNase activity|7-methylxanthosine ribohydrolase activity				KEGG_REACTION:R07918|RHEA:10880|MetaCyc:RXN-7597|EC:3.2.2.25									molecular_function											owl:Class	
GO:0047818	biolink:NamedThing	D-fuconate dehydratase activity	Catalysis of the reaction: D-fuconate = 2-dehydro-3-deoxy-D-fuconate + H(2)O.	tmpzr1t_l9r_go_relaxed.owl	D-fuconate hydro-lyase (2-dehydro-3-deoxy-D-fuconate-forming)|D-fuconate hydratase activity|D-fuconate hydro-lyase activity				EC:4.2.1.67|MetaCyc:D-FUCONATE-HYDRATASE-RXN|KEGG_REACTION:R03671|RHEA:12949									molecular_function											owl:Class	
GO:0033997	biolink:NamedThing	inulin fructotransferase (DFA-I-forming) activity	Catalysis of the reaction: [(2->1)-beta-D-fructosyl](n) = [(2->1)-beta-D-fructosyl](n-1) + alpha-D-fructofuranose-beta-D-fructofuranose 1,2':1,2'-dianhydride. This reaction is the production of alpha-D-fructofuranose beta-D-fructofuranose 1,2':2,1'-dianhydride (DFA I) by successively eliminating the diminishing (2->1)-beta-D-fructan (inulin) chain from the terminal D-fructosyl-D-fructosyl disaccharide.	tmpzr1t_l9r_go_relaxed.owl	inulin D-fructosyl-D-fructosyltransferase (1,2':1',2-dianhydride-forming) activity|inulin D-fructosyl-D-fructosyltransferase (forming alpha-D-fructofuranose beta-D-fructofuranose 1,2':1',2-dianhydride) activity|inulin fructotransferase (DFA-I-producing) activity|inulin fructotransferase (depolymerizing, difructofuranose-1,2':2',1-dianhydride-forming) activity|2,1-beta-D-fructan lyase (alpha-D-fructofuranose-beta-D-fructofuranose-1,2':2,1'-dianhydride-forming) activity				EC:4.2.2.17|MetaCyc:4.2.2.17-RXN									molecular_function											owl:Class	
GO:0102213	biolink:NamedThing	in-chain hydroxy fatty acyl-CoA synthetase activity	Catalysis of the reaction: coenzyme A + ATP + an in-chain hydroxy fatty acid = diphosphoric acid + AMP + a in-chain hydroxyacyl-CoA.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-12184									molecular_function											owl:Class	
GO:0050574	biolink:NamedThing	2-(R)-hydroxypropyl-CoM dehydrogenase activity	Catalysis of the reaction: 2-(R)-hydroxypropyl-coenzyme M + NAD(+) = 2-oxopropyl-coenzyme M + H(+) + NADH.	tmpzr1t_l9r_go_relaxed.owl	2-(2-(R)-hydroxypropylthio)ethanesulfonate dehydrogenase activity|2-[2-(R)-hydroxypropylthio]ethanesulfonate:NAD+ oxidoreductase activity				RHEA:13249|EC:1.1.1.268|MetaCyc:1.1.1.268-RXN|UM-BBD_reactionID:r0852|KEGG_REACTION:R05689									molecular_function											owl:Class	
GO:1901967	biolink:NamedThing	negative regulation of cellular response to iron ion starvation	Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to iron ion starvation.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of cellular response to iron ion starvation|down regulation of cellular response to iron ion starvation|downregulation of cellular response to iron ion starvation|inhibition of cellular response to iron ion starvation							al	2013-02-21T11:36:02Z					biological_process											owl:Class	
GO:0004092	biolink:NamedThing	carnitine O-acetyltransferase activity	Catalysis of the reaction: acetyl-CoA + carnitine = (R)-O-acetylcarnitine + CoA.	tmpzr1t_l9r_go_relaxed.owl	carnitine O-acetyltransferase II activity|carnitine-acetyl-CoA transferase activity|CATC|carnitine acetyl coenzyme A transferase activity|acetyl-CoA:carnitine O-acetyltransferase activity|acetyl-CoA-carnitine O-acetyltransferase activity|acetylcarnitine transferase activity|carnitine O-acetyltransferase I activity|carnitine acetyltransferase activity|carnitine acetylase activity				EC:2.3.1.7|Reactome:R-HSA-390291|Reactome:R-HSA-390284|RHEA:21136|KEGG_REACTION:R02396|MetaCyc:CARNITINE-O-ACETYLTRANSFERASE-RXN							GO:0004093|GO:0004094		molecular_function											owl:Class	
GO:0050376	biolink:NamedThing	UDP-glucosamine 4-epimerase activity	Catalysis of the reaction: UDP-glucosamine = UDP-galactosamine.	tmpzr1t_l9r_go_relaxed.owl	UDPglucosamine 4-epimerase activity|UDP-glucosamine epimerase activity				EC:5.1.3.16|MetaCyc:UDP-GLUCOSAMINE-EPIMERASE-RXN|RHEA:23492									molecular_function											owl:Class	
GO:0003111	biolink:NamedThing	positive regulation of heart rate by circulating epinephrine	The process in which the secretion of epinephrine into the bloodstream increases the rate of heart muscle contraction.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of heart rate by circulating adrenaline													biological_process											owl:Class	
GO:0047832	biolink:NamedThing	D-pinitol dehydrogenase activity	Catalysis of the reaction: 5D-5-O-methyl-chiro-inositol + NADP(+) = 2D-5-O-methyl-2,3,5/4,6-pentahydroxycyclohexanone + H(+) + NADPH.	tmpzr1t_l9r_go_relaxed.owl	5D-5-O-methyl-chiro-inositol:NADP+ oxidoreductase activity|1D-3-O-methyl-chiro-inositol:NADP+ oxidoreductase activity				KEGG_REACTION:R03498|MetaCyc:D-PINITOL-DEHYDROGENASE-RXN|EC:1.1.1.142|RHEA:20437									molecular_function											owl:Class	
GO:0019142	biolink:NamedThing	2-hydroxyglutarate synthase activity	Catalysis of the reaction: glyoxylate + H(2)O + propanoyl-CoA = 2-hydroxyglutarate + CoA + H(+).	tmpzr1t_l9r_go_relaxed.owl	hydroxyglutarate synthase activity|propanoyl-CoA:glyoxylate C-propanoyltransferase (thioester-hydrolysing, 2-carboxyethyl-forming)|2-hydroxyglutarate glyoxylate-lyase (CoA-propanoylating) activity|2-hydroxyglutaric synthetase activity|2-hydroxyglutaratic synthetase activity|alpha-hydroxyglutarate synthase activity				RHEA:19185|KEGG_REACTION:R00932|EC:2.3.3.11|MetaCyc:HYDGLUTSYN-RXN	Note that this function was formerly EC:4.1.3.9.								molecular_function											owl:Class	
GO:0035409	biolink:NamedThing	histone H3-Y41 phosphorylation	The modification of histone H3 by the addition of a phosphate group to a tyrosine residue at position 41 of the histone.	tmpzr1t_l9r_go_relaxed.owl								bf	2010-03-24T10:13:13Z					biological_process											owl:Class	
GO:0031720	biolink:NamedThing	haptoglobin binding	Binding to a haptoglobin, any alpha2 globulin of blood plasma that can combine with free oxyhemoglobin to form a stable complex.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0004134	biolink:NamedThing	4-alpha-glucanotransferase activity	Catalysis of the transfer of a segment of a (1->4)-alpha-D-glucan to a new 4-position in an acceptor, which may be glucose or (1->4)-alpha-D-glucan.	tmpzr1t_l9r_go_relaxed.owl	dextrin glycosyltransferase activity|D-enzyme activity|debranching enzyme maltodextrin glycosyltransferase activity|1,4-alpha-D-glucan:1,4-alpha-D-glucan 4-alpha-D-glycosyltransferase activity|amylomaltase activity|disproportionating enzyme activity|oligo-1,4-1,4-glucantransferase activity|dextrin transglycosylase activity				MetaCyc:AMYLOMALT-RXN|MetaCyc:RXN-9023|MetaCyc:RXN-1828|EC:2.4.1.25|Reactome:R-HSA-71552									molecular_function											owl:Class	
GO:0102863	biolink:NamedThing	1-18:3-2-18:1-phosphatidylcholine desaturase activity	Catalysis of the reaction: 1-18:3-2-18:1-phosphatidylcholine + O2 + a reduced electron acceptor <=> 1-18:3-2-18:2-phosphatidylcholine + 2 H2O + an oxidized electron acceptor.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-8330									molecular_function											owl:Class	
GO:0047783	biolink:NamedThing	corticosterone 18-monooxygenase activity	Catalysis of the reaction: corticosterone + reduced adrenal ferredoxin + O2 = 18-hydroxycorticosterone + oxidized adrenal ferredoxin + H2O.	tmpzr1t_l9r_go_relaxed.owl	corticosterone methyl oxidase activity|corticosterone,reduced-adrenal-ferredoxin:oxygen oxidoreductase (18-hydroxylating)|corticosterone 18-hydroxylase activity				EC:1.14.15.5|RHEA:11872|MetaCyc:CORTICOSTERONE-18-MONOOXYGENASE-RXN									molecular_function											owl:Class	
GO:0047547	biolink:NamedThing	2-methylcitrate dehydratase activity	Catalysis of the reaction: (2S,3S)-2-methylcitrate = cis-2-methylaconitate + H(2)O.	tmpzr1t_l9r_go_relaxed.owl	(2S,3S)-2-hydroxybutane-1,2,3-tricarboxylate hydro-lyase [(Z)-but-2-ene-1,2,3-tricarboxylate-forming]|prpD|2-methylcitrate hydro-lyase activity|2-hydroxybutane-1,2,3-tricarboxylate hydro-lyase activity				MetaCyc:2-METHYLCITRATE-DEHYDRATASE-RXN|KEGG_REACTION:R04424|EC:4.2.1.79|RHEA:17725									molecular_function											owl:Class	
GO:0070976	biolink:NamedThing	TIR domain binding	Binding to a Toll-Interleukin receptor (TIR) domain of a protein. The TIR domain is an intracellular 200 residue domain that is found in the Toll protein, the interleukin-1 receptor (IL-1R), and MyD88; it contains three highly-conserved regions, and mediates protein-protein interactions between the Toll-like receptors (TLRs) and signal-transduction components.	tmpzr1t_l9r_go_relaxed.owl	Toll-Interleukin receptor domain binding							mah	2009-10-02T01:17:29Z					molecular_function											owl:Class	
GO:0043720	biolink:NamedThing	3-keto-5-aminohexanoate cleavage activity	Catalysis of the reaction: 3-keto-5-aminohexanoate + acetyl-CoA = L-3-aminobutyryl-CoA + acetoacetate.	tmpzr1t_l9r_go_relaxed.owl	3-keto-5-aminohexanoate cleavage enzyme				RHEA:31555|MetaCyc:R125-RXN									molecular_function											owl:Class	
GO:0034948	biolink:NamedThing	2,6-dihydroxypseudooxynicotine hydrolase activity	Catalysis of the reaction: 2,6-dihydroxypseudooxynicotine + H2O = 2,6-dihydroxypyridine + 4-methylaminobutyrate.	tmpzr1t_l9r_go_relaxed.owl					EC:3.7.1.-|UM-BBD_reactionID:r0482									molecular_function											owl:Class	
GO:0052674	biolink:NamedThing	ent-pimara-9(11),15-diene synthase activity	Catalysis of the reaction: ent-copalyl diphosphate = ent-pimara-9(11),15-diene + diphosphate.	tmpzr1t_l9r_go_relaxed.owl	ent-copalyl-diphosphate diphosphate-lyase [ent-pimara-9(11),15-diene-forming] activity|PMD synthase activity				MetaCyc:RXN-9299|EC:4.2.3.31|RHEA:25544									molecular_function											owl:Class	
GO:0005127	biolink:NamedThing	ciliary neurotrophic factor receptor binding	Binding to a ciliary neurotrophic factor receptor.	tmpzr1t_l9r_go_relaxed.owl	ciliary neurotrophic factor receptor ligand|ciliary neurotrophic factor													molecular_function											owl:Class	
GO:0098603	biolink:NamedThing	selenol Se-methyltransferase activity	Catalysis of the reaction: R + Se-Adenosylselenomethionine => CH3-R + Se-Adenosyl-L-selenohomocysteine.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-2408544									molecular_function											owl:Class	
GO:0034548	biolink:NamedThing	N-cyclopropylammeline deaminase activity	Catalysis of the reaction: N-cyclopropylammeline + H2O = N-cyclopropylammelide + NH3.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-8019|UM-BBD_reactionID:r0826									molecular_function											owl:Class	
GO:0035328	biolink:NamedThing	transcriptionally silent chromatin	The ordered and organized complex of DNA and protein that forms regions of the chromosome that are not being actively transcribed.	tmpzr1t_l9r_go_relaxed.owl	transcriptionally inactive chromatin							bf	2010-02-26T10:24:13Z					cellular_component											owl:Class	
GO:0047875	biolink:NamedThing	ecdysone oxidase activity	Catalysis of the reaction: Ecdysone + O(2) = 3-dehydroecdysone + H(2)O(2).	tmpzr1t_l9r_go_relaxed.owl	ecdysone:oxygen 3-oxidoreductase activity|beta-ecdysone oxidase activity				KEGG_REACTION:R02373|RHEA:11796|MetaCyc:ECDYSONE-OXIDASE-RXN|EC:1.1.3.16									molecular_function											owl:Class	
GO:0004827	biolink:NamedThing	proline-tRNA ligase activity	Catalysis of the reaction: ATP + L-proline + tRNA(Pro) = AMP + diphosphate + L-prolyl-tRNA(Pro).	tmpzr1t_l9r_go_relaxed.owl	prolyl-s-RNA synthetase activity|L-proline:tRNAPro ligase (AMP-forming)|prolyl-transfer ribonucleic acid synthetase activity|prolyl-transfer ribonucleate synthetase activity|prolyl-transferRNA synthetase activity|prolinyl-tRNA ligase activity|prolyl-tRNA synthetase activity|proline translase activity				Reactome:R-HSA-379865|Reactome:R-HSA-380198|EC:6.1.1.15|MetaCyc:PROLINE--TRNA-LIGASE-RXN|RHEA:14305									molecular_function											owl:Class	
GO:0004328	biolink:NamedThing	formamidase activity	Catalysis of the reaction: formamide + H(2)O = formate + NH(4)(+).	tmpzr1t_l9r_go_relaxed.owl	formamide hydrolase activity|formamide amidohydrolase activity				UM-BBD_reactionID:r0873|EC:3.5.1.49|RHEA:21948|MetaCyc:FORMAMIDASE-RXN|KEGG_REACTION:R00524							GO:0034566		molecular_function											owl:Class	
GO:0140693	biolink:NamedThing	molecular condensate scaffold activity	Binding and bringing together two or more macromolecules in contact, permitting those molecules to organize as a molecular condensate.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/21937						pg	2021-08-09T15:13:52Z					molecular_function											owl:Class	
GO:0062211	biolink:NamedThing	root regeneration	The the regeneration process by which a damaged or lost root regrows or re-differentiates. This process may occur via de-differentiation and subsequent reprogramming of somatic cells or activation of existing undifferentiated (meristematic) cells to form a new root meristem and subsequently new root.	tmpzr1t_l9r_go_relaxed.owl								dph	2020-02-21T12:47:41Z					biological_process											owl:Class	
GO:0110050	biolink:NamedThing	deaminated glutathione amidase activity	Catalysis of the reaction: N-(4-oxoglutarate)-L-cysteinylglycine + H(2)O = 2-oxoglutarate + L-cysteinylglycine.	tmpzr1t_l9r_go_relaxed.owl						N-(4-oxoglutarate)-L-cysteinylglycine = deaminated glutathione		kmv	2017-08-31T19:19:11Z					molecular_function											owl:Class	
GO:0018796	biolink:NamedThing	4,5-dihydroxyphthalate decarboxylase activity	Catalysis of the reaction: 4,5-dihydroxyphthalate = 3,4-dihydroxybenzoate + CO2.	tmpzr1t_l9r_go_relaxed.owl	4,5-dihydroxyphthalate carboxy-lyase (3,4-dihydroxybenzoate-forming)|4,5-dihydroxyphthalate carboxy-lyase activity				RHEA:24184|MetaCyc:45-DIHYDROXYPHTHALATE-DECARBOXYLASE-RXN|EC:4.1.1.55|UM-BBD_enzymeID:e0106									molecular_function											owl:Class	
GO:0042131	biolink:NamedThing	thiamine phosphate phosphatase activity	Catalysis of the reaction: thiamine phosphate + H2O = thiamine + phosphate.	tmpzr1t_l9r_go_relaxed.owl	thiamin monophosphate phosphatase|thiamin phosphate phosphatase activity|ThMPase													molecular_function											owl:Class	
GO:1904065	biolink:NamedThing	G protein-coupled acetylcholine receptor signaling pathway involved in positive regulation of acetylcholine secretion, neurotransmission	Any G protein-coupled acetylcholine receptor signaling pathway that is involved in positive regulation of acetylcholine secretion, neurotransmission.	tmpzr1t_l9r_go_relaxed.owl	acetylcholine receptor signalling, muscarinic pathway involved in up regulation of acetylcholine secretion|G-protein coupled acetylcholine receptor signaling pathway involved in activation of acetylcholine secretion|G-protein coupled acetylcholine receptor signaling pathway involved in positive regulation of acetylcholine secretion, neurotransmission|muscarinic acetylcholine receptor signaling pathway involved in positive regulation of acetylcholine secretion, neurotransmission|G-protein coupled acetylcholine receptor signaling pathway involved in up regulation of acetylcholine secretion|acetylcholine receptor signalling, muscarinic pathway involved in upregulation of acetylcholine secretion|acetylcholine receptor signalling, muscarinic pathway involved in positive regulation of acetylcholine secretion, neurotransmission|G-protein coupled acetylcholine receptor signaling pathway involved in upregulation of acetylcholine secretion|G-protein coupled acetylcholine receptor signaling pathway involved in stimulation of acetylcholine secretion|muscarinic acetylcholine receptor signaling pathway involved in activation of acetylcholine secretion|muscarinic acetylcholine receptor signaling pathway involved in up regulation of acetylcholine secretion|acetylcholine receptor signalling, muscarinic pathway involved in activation of acetylcholine secretion|acetylcholine receptor signalling, muscarinic pathway involved in stimulation of acetylcholine secretion|acetylcholine receptor signalling, muscarinic pathway involved in up-regulation of acetylcholine secretion|muscarinic acetylcholine receptor signaling pathway involved in upregulation of acetylcholine secretion|muscarinic acetylcholine receptor signaling pathway involved in up-regulation of acetylcholine secretion|G-protein coupled acetylcholine receptor signaling pathway involved in up-regulation of acetylcholine secretion|muscarinic acetylcholine receptor signaling pathway involved in stimulation of acetylcholine secretion							kmv	2015-03-19T15:28:47Z					biological_process											owl:Class	
GO:0018395	biolink:NamedThing	peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine	The hydroxylation of peptidyl-lysine to peptidyl-5-hydroxy-L-lysine.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0028									biological_process											owl:Class	
GO:0047206	biolink:NamedThing	UDP-N-acetylmuramoylpentapeptide-lysine N6-alanyltransferase activity	Catalysis of the reaction: UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-D-alanyl-D-alanine + L-alanyl-tRNA = UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-N6-(L-alanyl)-L-lysyl-D-alanyl-D-alanine + tRNA.	tmpzr1t_l9r_go_relaxed.owl	uridine diphosphoacetylmuramoylpentapeptide lysine N(6)-alanyltransferase activity|L-alanyl-tRNA:UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-D-alanyl-D-alanine 6-N-alanyltransferase activity|L-alanyl-tRNA:UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-D-alanyl-D-alanine N6-alanyltransferase activity|alanyl-transfer ribonucleate-uridine diphosphoacetylmuramoylpentapeptide transferase activity|UDP-N-acetylmuramoylpentapeptide lysine N6-alanyltransferase activity|uridine diphosphoacetylmuramoylpentapeptide lysine N6-alanyltransferase activity|UDP-N-acetylmuramoylpentapeptide lysine N(6)-alanyltransferase activity				MetaCyc:2.3.2.10-RXN|EC:2.3.2.10|RHEA:12432									molecular_function											owl:Class	
GO:0047993	biolink:NamedThing	hydroxymalonate dehydrogenase activity	Catalysis of the reaction: hydroxymalonate + NAD(+) = H(+) + NADH + oxomalonate.	tmpzr1t_l9r_go_relaxed.owl	hydroxymalonate:NAD+ oxidoreductase activity				EC:1.1.1.167|KEGG_REACTION:R02969|MetaCyc:HYDROXYMALONATE-DEHYDROGENASE-RXN|RHEA:11284									molecular_function											owl:Class	
GO:0018791	biolink:NamedThing	2-hydroxy-3-carboxy-6-oxo-7-methylocta-2,4-dienoate decarboxylase activity	Catalysis of the reaction: 2-hydroxy-3-carboxy-6-oxo-7-methylocta-2,4-dienoate = CO2 + 2-hydroxy-6-oxo-7-methylocta-2,4-dienoate.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0398									molecular_function											owl:Class	
GO:0008961	biolink:NamedThing	phosphatidylglycerol-prolipoprotein diacylglyceryl transferase activity	Catalysis of the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the prospective N-terminal cysteine residue in an unmodified prolipoprotein.	tmpzr1t_l9r_go_relaxed.owl					EC:2.5.1.145|RHEA:56712									molecular_function											owl:Class	
GO:0050345	biolink:NamedThing	trans-epoxysuccinate hydrolase activity	Catalysis of the reaction: trans-2,3-epoxysuccinate + H(2)O = (2R,3S)-tartrate.	tmpzr1t_l9r_go_relaxed.owl	trans-2,3-epoxysuccinate hydrolase activity|tartrate epoxydase activity|trans-epoxysuccinate hydratase activity				KEGG_REACTION:R02547|MetaCyc:TRANS-EPOXYSUCCINATE-HYDROLASE-RXN|RHEA:20740|EC:3.3.2.4									molecular_function											owl:Class	
GO:0002936	biolink:NamedThing	bradykinin biosynthetic process	The chemical reactions and pathways resulting in the formation of the peptide hormone bradykinin.	tmpzr1t_l9r_go_relaxed.owl								hjd	2012-10-17T14:24:24Z					biological_process											owl:Class	
GO:0071860	biolink:NamedThing	proctolin receptor binding	Binding to a proctolin receptor.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-09-10T03:24:19Z					molecular_function											owl:Class	
GO:0001604	biolink:NamedThing	urotensin II receptor activity	Combining with urotensin II to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0016277	biolink:NamedThing	[myelin basic protein]-arginine N-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + (myelin basic protein)-arginine = S-adenosyl-L-homocysteine + (myelin basic protein)-N(omega)-methyl-arginine.	tmpzr1t_l9r_go_relaxed.owl	S-adenosyl-L-methionine:myelin-basic-protein-arginine nomega-methyltransferase activity|myelin basic protein-arginine N-methyltransferase activity|myelin basic protein methylase activity|S-adenosyl-L-methionine:myelin-basic-protein-arginine omega-N-methyltransferase activity|myelin basic protein methylase I|protein methylase I activity													molecular_function											owl:Class	
GO:0048173	biolink:NamedThing	positive regulation of short-term neuronal synaptic plasticity	A process that increases short-term neuronal synaptic plasticity, the ability of neuronal synapses to change in the short-term as circumstances require. Short-term neuronal synaptic plasticity generally involves increasing or decreasing synaptic sensitivity.	tmpzr1t_l9r_go_relaxed.owl	activation of short-term neuronal synaptic plasticity|up-regulation of short-term neuronal synaptic plasticity|up regulation of short-term neuronal synaptic plasticity|upregulation of short-term neuronal synaptic plasticity|stimulation of short-term neuronal synaptic plasticity					Note that the syntax of the definition of this term is different from the usual regulation syntax because it describes regulation of a trait rather than regulation of a process.								biological_process											owl:Class	
GO:0048172	biolink:NamedThing	regulation of short-term neuronal synaptic plasticity	A process that modulates short-term neuronal synaptic plasticity, the ability of neuronal synapses to change in the short-term as circumstances require. Short-term neuronal synaptic plasticity generally involves increasing or decreasing synaptic sensitivity.	tmpzr1t_l9r_go_relaxed.owl						Note that the syntax of the definition of this term is different from the usual regulation syntax because it describes regulation of a trait rather than regulation of a process.								biological_process											owl:Class	
GO:0140714	biolink:NamedThing	large ribosomal subunit pre-assembly complex	A protein complex that assists early maturation of nascent 60S ribosomal subunits. The complex interacts with the large ribosomal subunit rRNA via one of the components (Urb2 in S. cerevisiae) and requires a RNA helicase (Dbp6 in S. cerevisiae).	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/15279						pg	2021-09-15T12:17:56Z					cellular_component											owl:Class	
GO:0099573	biolink:NamedThing	glutamatergic postsynaptic density	The post-synaptic specialization of a glutamatergic excitatory synapse.	tmpzr1t_l9r_go_relaxed.owl	postsynaptic specialization, glutamatergic neuron-to-neuron synapse													cellular_component											owl:Class	
GO:0019948	biolink:NamedThing	SUMO activating enzyme activity	Catalysis of the activation of the proteolytically processed small ubiquitin-related modifier SUMO, through the formation of an ATP-dependent high-energy thiolester bond.	tmpzr1t_l9r_go_relaxed.owl	SUMO E1 activator enzyme|SMT3 activating enzyme				Reactome:R-HSA-2993784|Reactome:R-HSA-2993781|Reactome:R-HSA-2990833							GO:0017115		molecular_function											owl:Class	
GO:0008489	biolink:NamedThing	UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity	Catalysis of the reaction: UDP-D-galactose + a glucosylceramide = a lactosylceramide + uridine-5'-diphosphate. The glucosylceramide has sphinganine as the long chain base.	tmpzr1t_l9r_go_relaxed.owl	lactosylceramide synthase activity|UDP-galactose glucosylceramide beta-1,4-galactosyltransferase activity|LacCer synthase activity				MetaCyc:RXN-10764									molecular_function											owl:Class	
GO:0120185	biolink:NamedThing	MBF transcription complex assembly	The aggregation, arrangement and bonding together of a set of components to form an MBF transcription complex.	tmpzr1t_l9r_go_relaxed.owl	Mlu1-box binding factor assembly|DSC1 transcription factor complex assembly|MBF complex assembly							krc	2018-07-13T23:21:43Z					biological_process											owl:Class	
GO:0015048	biolink:NamedThing	phthalate dioxygenase reductase activity	Catalysis of the transfer of electrons between pyridine nucleotides (obligatory two-electron carriers) and hemes or (2Fe-2S) centers (obligatory one-electron carriers) in respiration, photosynthesis, and many oxygenase systems.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0061587	biolink:NamedThing	transfer RNA gene-mediated silencing	The chromatin silencing that results in the inhibition of RNA polymerase II-transcribed genes located in the vicinity of tRNA genes.	tmpzr1t_l9r_go_relaxed.owl	transfer RNA gene-mediated gene silencing|tgm silencing|tRNA gene-mediated gene silencing|transfer RNA gene-mediated chromatin silencing|tRNA gene-mediated chromatin silencing	https://github.com/geneontology/go-ontology/issues/22060						dph	2014-02-05T09:03:59Z					biological_process											owl:Class	
GO:0034237	biolink:NamedThing	protein kinase A regulatory subunit binding	Binding to one or both of the regulatory subunits of protein kinase A.	tmpzr1t_l9r_go_relaxed.owl	protein kinase A anchoring activity|PKA regulatory subunit binding													molecular_function											owl:Class	
GO:0051432	biolink:NamedThing	BH1 domain binding	Binding to a BH1 protein domain, present in Bcl-2 family members. Proteins that act as inhibitors of apoptosis harbour at least three BH domains: BH1, BH2 and BH3; the BH1 and BH2 domains are found in all death antagonists of the Bcl-2 family but only in one class of death agonists.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0050362	biolink:NamedThing	L-tryptophan:2-oxoglutarate aminotransferase activity	Catalysis of the reaction: L-tryptophan + 2-oxoglutarate = indolepyruvate + L-glutamate.	tmpzr1t_l9r_go_relaxed.owl	tryptophan aminotransferase activity|L-tryptophan aminotransferase activity|tryptophan transaminase activity|L-phenylalanine-2-oxoglutarate aminotransferase activity|L-tryptophan transaminase activity|hydroxytryptophan aminotransferase activity|5-hydroxytryptophan-ketoglutaric transaminase activity				EC:2.6.1.27|RHEA:14093|MetaCyc:TRYPTOPHAN-AMINOTRANSFERASE-RXN									molecular_function											owl:Class	
GO:0015452	biolink:NamedThing	methyl transfer-driven active transmembrane transporter activity	Primary active transport of a solute across a membrane driven by a methyl transfer reaction. Primary active transport is catalysis of the transport of a solute across a membrane, up the solute's concentration gradient, by binding the solute and undergoing a series of conformational changes. Transport works equally well in either direction and is driven by a primary energy source.	tmpzr1t_l9r_go_relaxed.owl	Methyltransfer-driven transporters				TC:3.C									molecular_function											owl:Class	
GO:0018456	biolink:NamedThing	aryl-alcohol dehydrogenase (NAD+) activity	Catalysis of the reaction: an aromatic alcohol + NAD+ = an aromatic aldehyde + NADH + H+.	tmpzr1t_l9r_go_relaxed.owl	benzyl alcohol dehydrogenase activity|aryl-alcohol:NAD+ oxidoreductase activity|p-hydroxybenzyl alcohol dehydrogenase activity				RHEA:12076|UM-BBD_enzymeID:e0019|EC:1.1.1.90|MetaCyc:ARYL-ALCOHOL-DEHYDROGENASE-RXN									molecular_function											owl:Class	
GO:0019196	biolink:NamedThing	galactosamine transmembrane transporter activity	Enables the transfer of galactosamine from one side of a membrane to the other. Galactosamine is an aminodeoxysugar; D-galactosamine is a constituent of some glycolipids and glycosaminoglycans, commonly as its N-acetyl derivative.	tmpzr1t_l9r_go_relaxed.owl	galactosamine porter activity											GO:0019195		molecular_function											owl:Class	
GO:0015153	biolink:NamedThing	rhamnose transmembrane transporter activity	Enables the transfer of rhamnose from one side of a membrane to the other. Rhamnose occurs commonly as a compound of plant glycosides, in polysaccharides of gums and mucilages, and in bacterial polysaccharides. It is also a component of some plant cell wall polysaccharides and frequently acts as the sugar components of flavonoids.	tmpzr1t_l9r_go_relaxed.owl	ATPase-coupled rhamnose transmembrane transporter activity|ATP-dependent rhamnose transmembrane transporter activity|rhamnose-transporting ATPase activity	https://github.com/geneontology/go-ontology/issues/17289			RHEA:34995							GO:0033297		molecular_function											owl:Class	
GO:0102768	biolink:NamedThing	anthocyanidin synthase activity	Catalysis of the reaction: flavan-3,3',4,4',5,5',7-heptol + O2 + 2-oxoglutarate = H+ + delphinidin + 2 H2O + carbon dioxide + succinate.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-7785									molecular_function											owl:Class	
GO:0047432	biolink:NamedThing	2,2-dialkylglycine decarboxylase (pyruvate) activity	Catalysis of the reaction: 2,2-dialkylglycine + H(+) + pyruvate = L-alanine + CO(2) + dialkyl ketone.	tmpzr1t_l9r_go_relaxed.owl	dialkylamino-acid decarboxylase (pyruvate)|2,2-dialkylglycine carboxy-lyase (amino-transferring; L-alanine-forming)|dialkyl amino acid (pyruvate) decarboxylase activity|2,2-dialkyl-2-amino acid-pyruvate aminotransferase activity|alpha-dialkyl amino acid transaminase activity|L-alanine-alpha-ketobutyrate aminotransferase activity|2,2-dialkylglycine carboxy-lyase (amino-transferring)				MetaCyc:4.1.1.64-RXN|KEGG_REACTION:R03854|RHEA:16073|EC:4.1.1.64									molecular_function											owl:Class	
GO:0102080	biolink:NamedThing	phenylacetyl-coenzyme A:glycine N-acyltransferase activity	Catalysis of the reaction: phenylacetyl-CoA + glycine <=> H+ + phenylacetylglycine + coenzyme A.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-10821|RHEA:27850|EC:2.3.1.192									molecular_function											owl:Class	
GO:0004578	biolink:NamedThing	chitobiosyldiphosphodolichol beta-mannosyltransferase activity	Catalysis of the reaction: GDP-mannose + chitobiosyldiphosphodolichol = GDP + beta-D-mannosylchitobiosyldiphosphodolichol.	tmpzr1t_l9r_go_relaxed.owl	GDP-mannose:chitobiosyldiphosphodolichol beta-D-mannosyltransferase activity|guanosine diphosphomannose-dolichol diphosphochitobiose mannosyltransferase activity|GDP-mannose-dolichol diphosphochitobiose mannosyltransferase activity				EC:2.4.1.142|MetaCyc:2.4.1.142-RXN|RHEA:13865|Reactome:R-HSA-446218|Reactome:R-HSA-4549382									molecular_function											owl:Class	
GO:0018607	biolink:NamedThing	1-indanone monooxygenase activity	Catalysis of the reaction: 1-indanone + NADPH + 1/2 O2 = NADP+ + 3,4-dihydrocoumarin.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0417|EC:1.14.12.-									molecular_function											owl:Class	
GO:0070499	biolink:NamedThing	exosporium assembly	A process that is carried out at the cellular level which results in the formation of an exosporium, the outermost layer of a bacterial endospore.	tmpzr1t_l9r_go_relaxed.owl	exosporium formation													biological_process											owl:Class	
GO:0035526	biolink:NamedThing	retrograde transport, plasma membrane to Golgi	The directed movement of substances from the plasma membrane back to the trans-Golgi network, mediated by vesicles.	tmpzr1t_l9r_go_relaxed.owl								bf	2010-05-05T10:52:49Z					biological_process											owl:Class	
GO:0050112	biolink:NamedThing	inositol 2-dehydrogenase activity	Catalysis of the reaction: myo-inositol + NAD(+) = 2,4,6/3,5-pentahydroxycyclohexanone + H(+) + NADH.	tmpzr1t_l9r_go_relaxed.owl	inositol:NAD 2-dehydrogenase activity|myo-inositol 2-dehydrogenase activity				KEGG_REACTION:R01183|EC:1.1.1.18|MetaCyc:MYO-INOSITOL-2-DEHYDROGENASE-RXN|RHEA:16949									molecular_function											owl:Class	
GO:0044202	biolink:NamedThing	host cell nuclear outer membrane	The outer, i.e. cytoplasm-facing, lipid bilayer of the host nuclear envelope; continuous with the endoplasmic reticulum of the host cell and sometimes studded with ribosomes.	tmpzr1t_l9r_go_relaxed.owl								jl	2009-10-21T11:10:23Z					cellular_component											owl:Class	
GO:0106234	biolink:NamedThing	outer membrane protein complex	Any protein complex that is part of the bacterial outer membrane. An example In E.coli, is RcsF associated with any one of several outer membrane beta-barrel proteins (OMPs), such as OmpA, OmpF, or OmpcC.	tmpzr1t_l9r_go_relaxed.owl								hjd	2019-11-07T19:20:43Z					cellular_component											owl:Class	
GO:0018068	biolink:NamedThing	peptidyl-L-2',4',5'-topaquinone biosynthetic process from peptidyl-tyrosine	The modification of protein tyrosine to L-2',4',5'-topaquinone, characteristic of the active site of copper amine oxidases.	tmpzr1t_l9r_go_relaxed.owl	peptidyl-L-2',4',5'-topaquinone anabolism from peptidyl-tyrosine|peptidyl-L-2',4',5'-topaquinone formation from peptidyl-tyrosine|peptidyl-L-2',4',5'-topaquinone synthesis from peptidyl-tyrosine				RESID:AA0147									biological_process											owl:Class	
GO:0071065	biolink:NamedThing	alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex	A protein complex that consists of an alpha9-beta1 integrin complex bound to vascular cell adhesion molecule-1.	tmpzr1t_l9r_go_relaxed.owl	ITGA9-ITGB1-VCAM1 complex							mah	2009-11-03T04:04:01Z					cellular_component											owl:Class	
GO:0033149	biolink:NamedThing	FFAT motif binding	Binding to a FFAT motif, a short motif containing diphenylalanine in an acidic tract that targets proteins to the cytosolic surface of the ER and to the nuclear membrane by binding directly to members of the VAP (VAMP-associated protein) protein family.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1903929	biolink:NamedThing	primary palate development	The process whose specific outcome is the progression of a primary palate over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl	processus palatinus medianus development|primary palate process development|primitive palate development|palatum primarium development							cls	2015-02-11T22:42:38Z					biological_process											owl:Class	
GO:0051265	biolink:NamedThing	diolein transacylation activity	Catalysis of the reaction: diolein + mono-olein = triolein + glycerol. Mono-olein, also known as mono-oleoylglycerol, is the monoglyceride formed from oleic acid, 9-octodecenoic acid; diolein is also known as dioleoylglycerol, and triolein as trioleoylglycerol and olein.	tmpzr1t_l9r_go_relaxed.owl	DOG transacylation|dioleoylglycerol transacylase activity|acyl-CoA-independent diolein transacylation|dioleoylglycerol O-acyltransferase activity													molecular_function											owl:Class	
GO:0018683	biolink:NamedThing	camphor 5-monooxygenase activity	Catalysis of the reaction: (+)-camphor + putidaredoxin + O2 = (+)-exo-5-hydroxycamphor + oxidized putidaredoxin + H2O.	tmpzr1t_l9r_go_relaxed.owl	camphor hydroxylase activity|camphor 5-exohydroxylase activity|2-bornanone 5-exo-hydroxylase activity|D-camphor-exo-hydroxylase activity|cytochrome p450-cam activity|bornanone 5-exo-hydroxylase activity|d-camphor monooxygenase activity|camphor 5-exo-hydroxylase activity|camphor methylene hydroxylase activity|methylene hydroxylase activity|camphor 5-exo-methylene hydroxylase activity|methylene monooxygenase activity|(+)-camphor,reduced putidaredoxin:oxygen oxidoreductase (5-hydroxylating)				MetaCyc:R541-RXN|UM-BBD_enzymeID:e0300|RHEA:13525|EC:1.14.15.1									molecular_function											owl:Class	
GO:0097492	biolink:NamedThing	sympathetic neuron axon guidance	The chemotaxis process that directs the migration of a sympathetic neuron axon growth cone to a specific target site in response to a combination of attractive and repulsive cues.	tmpzr1t_l9r_go_relaxed.owl	sympathetic neuron axon chemotaxis|sympathetic neuron axon pathfinding|sympathetic neuron axon growth cone guidance							pr	2013-07-10T11:50:52Z					biological_process											owl:Class	
GO:0001734	biolink:NamedThing	mRNA (N6-adenosine)-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + RRACH = S-adenosyl-L-homocysteine + RRm6ACH; R is a purine, and H is C, A, or U.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-72095									molecular_function											owl:Class	
GO:0099128	biolink:NamedThing	mitochondrial iron-sulfur cluster assembly complex	A protein complex consisting of frataxin, cysteine desulfurase, an accessory protein and a Fe-S scaffold protein. In human these genes correspond to FXN, NFS1, ISD11 and ISCU respectively. This complex assembles Fe-S clusters onto the scaffolding protein using the substrates ferrous iron, electrons, and sulfur from l-cysteine.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0098692	biolink:NamedThing	noradrenergic synapse	A synapse that uses noradrenaline as a neurotransmitter.	tmpzr1t_l9r_go_relaxed.owl								dos	2017-03-07T14:57:24Z					cellular_component											owl:Class	
GO:0015386	biolink:NamedThing	potassium:proton antiporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: K+(in) + H+(out) = K+(out) + H+(in).	tmpzr1t_l9r_go_relaxed.owl	potassium:hydrogen antiporter activity				RHEA:29467									molecular_function											owl:Class	
GO:0018038	biolink:NamedThing	C-terminal peptidyl-cysteine amidation	The formation of a C-terminal peptidyl-cysteine amide by hydrolysis and oxidation of an interior Cys-Gly peptide in a secreted protein.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0085									biological_process											owl:Class	
GO:0102318	biolink:NamedThing	2-deoxystreptamine glucosyltransferase activity	Catalysis of the reaction: 2-deoxystreptamine + UDP-alpha-D-glucose <=> 2'-deamino-2'-hydroxyparomamine + UDP(3-) + H+.	tmpzr1t_l9r_go_relaxed.owl					EC:2.4.1.284|MetaCyc:RXN-13121|RHEA:34063									molecular_function											owl:Class	
GO:0050699	biolink:NamedThing	WW domain binding	Binding to a WW domain of a protein, a small module composed of 40 amino acids and plays a role in mediating protein-protein interactions via proline-rich regions.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0018532	biolink:NamedThing	5,10-methenyl-5,6,7,8-tetrahydromethanopterin dehydrogenase activity	Catalysis of the reaction: N5,N10-methenyltetrahydromethanopterin + H2 = N5,N10-methylenetetrahydromethanopterin.	tmpzr1t_l9r_go_relaxed.owl	coenzyme F420-independent 5,10-methenyl-5,6,7,8-tetrahydromethanopterin dehydrogenase activity|F420-independent methylene-H4MPT dehydrogenase activity|coenzyme F420-independent methylene-H4MPT dehydrogenase activity|F420-independent 5,10-methenyl-5,6,7,8-tetrahydromethanopterin dehydrogenase activity				EC:1.5.99.-|UM-BBD_reactionID:r0353									molecular_function											owl:Class	
GO:0047667	biolink:NamedThing	AMP-thymidine kinase activity	Catalysis of the reaction: AMP + thymidine = adenosine + thymidine 5'-phosphate.	tmpzr1t_l9r_go_relaxed.owl	adenylate-nucleoside phosphotransferase activity|adenylic acid:deoxythymidine 5'-phosphotransferase activity|AMP:thymidine 5'-phosphotransferase activity|thymidine phosphotransferase activity|AMP:deoxythymidine kinase activity|AMP:dThd kinase activity|AMP:deoxythymidine 5'-phosphotransferase activity				MetaCyc:AMP--THYMIDINE-KINASE-RXN|RHEA:14913|EC:2.7.1.114									molecular_function											owl:Class	
GO:0047585	biolink:NamedThing	4-pyridoxolactonase activity	Catalysis of the reaction: 4-pyridoxolactone + H(2)O = 4-pyridoxate + H(+).	tmpzr1t_l9r_go_relaxed.owl	4-pyridoxolactone lactonohydrolase activity				KEGG_REACTION:R02992|EC:3.1.1.27|RHEA:14301|MetaCyc:4-PYRIDOXOLACTONASE-RXN									molecular_function											owl:Class	
GO:0036202	biolink:NamedThing	ent-cassa-12,15-diene 11-hydroxylase activity	Catalysis of the reaction: ent-cassa-12,15-diene + O2 + NADPH + H+ = ent-11beta-hydroxycassa-12,15-diene + NADP+ + H2O.	tmpzr1t_l9r_go_relaxed.owl	ent-cassadiene C11alpha-hydroxylase activity				KEGG_REACTION:R09866|RHEA:31967|EC:1.14.14.112			bf	2012-04-20T02:34:13Z					molecular_function											owl:Class	
GO:0050210	biolink:NamedThing	prenyl-diphosphatase activity	Catalysis of the reaction: prenyl diphosphate + H2O = prenol + diphosphate.	tmpzr1t_l9r_go_relaxed.owl	prenyl-pyrophosphatase activity|prenyl-diphosphate diphosphohydrolase activity|prenol pyrophosphatase activity|prenylphosphatase activity				EC:3.1.7.1|RHEA:21496|MetaCyc:PRENYL-PYROPHOSPHATASE-RXN									molecular_function											owl:Class	
GO:0042778	biolink:NamedThing	tRNA end turnover	The process in which the 3'-terminal CCA of a tRNA is removed and restored. This often happens to uncharged tRNA.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0030351	biolink:NamedThing	inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase activity	Catalysis of the reaction: inositol-1,3,4,5,6-pentakisphosphate + H2O = inositol-1,4,5,6-tetrakisphosphate + phosphate.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-1855163									molecular_function											owl:Class	
GO:0030577	biolink:NamedThing	Lands organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of Lands, a class of nuclear body that react against SP140 auto-antibodies.	tmpzr1t_l9r_go_relaxed.owl	Lands organisation|Lands organization and biogenesis|LYSP100-associated nuclear domain organization					See also the cellular component term 'Lands ; GO:0016606'.								biological_process											owl:Class	
GO:0019821	biolink:NamedThing	P3 peroxisome	A subform of peroxisome that corresponds to an intermediate in a peroxisome assembly pathway, which operates by conversion of peroxisomal subforms in the direction P1, P2 -> P3 -> P4 -> P5 -> P6. P3 peroxisomes are formed by fusion of P1 and P2 peroxisomes, and are distinguished from the other subforms on the bases of buoyant density and protein content.	tmpzr1t_l9r_go_relaxed.owl	peroxisome vesicle					Note that this peroxisome assembly pathway is described in the yeast Yarrowia lipolytica. See also the cellular component terms 'P1 peroxisome ; GO:0019819', 'P2 peroxisome ; GO:0019820', 'P4 peroxisome ; GO:0019822', 'P5 peroxisome ; GO:0019823', and 'P6 peroxisome ; GO:0019824'.								cellular_component											owl:Class	
GO:0004764	biolink:NamedThing	shikimate 3-dehydrogenase (NADP+) activity	Catalysis of the reaction: shikimate + NADP+ = 3-dehydroshikimate + NADPH + H+.	tmpzr1t_l9r_go_relaxed.owl	shikimate:NADP(+) 5-oxidoreductase activity|DHS reductase activity|5-dehydroshikimic reductase activity|5-dehydroshikimate reductase activity|shikimate:NADP(+) oxidoreductase activity|dehydroshikimic reductase activity|shikimate oxidoreductase activity				MetaCyc:SHIKIMATE-5-DEHYDROGENASE-RXN|KEGG_REACTION:R06847|EC:1.1.1.282|RHEA:17737|EC:1.1.1.25									molecular_function											owl:Class	
GO:0018760	biolink:NamedThing	thiocyanate hydrolase activity	Catalysis of the reaction: H(2)O + 2 H(+) + thiocyanate = carbonyl sulfide + NH(4)(+).	tmpzr1t_l9r_go_relaxed.owl	thiocyanate aminohydrolase activity				KEGG_REACTION:R05780|EC:3.5.5.8|MetaCyc:RXN-1761|RHEA:21464|UM-BBD_reactionID:r0598									molecular_function											owl:Class	
GO:0033661	biolink:NamedThing	effector-mediated defense to host-produced reactive oxygen species	A process mediated by a molecule secreted by a symbiont that results in the suppression of reactive oxygen species produced by the host as part of its innate immune response. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	inhibition by organism of defense-related host active oxygen species production|down-regulation by organism of defense-related host oxidative burst|suppression by symbiont of defense-related host reactive oxygen species production|downregulation by organism of defense-related host AOS production|negative regulation by organism of defense-related host reactive oxygen intermediate production|negative regulation by organism of defense-related host reactive oxidative species production|negative regulation by organism of defense-related host respiratory burst|negative regulation by organism of defense-related host ROI production|down regulation by organism of defense-related host metabolic burst|negative regulation by symbiont of defense-related host reactive oxygen species production|negative regulation by organism of defense-related host ROS production	https://github.com/geneontology/go-ontology/issues/18697												biological_process											owl:Class	
GO:0043750	biolink:NamedThing	phosphatidylinositol alpha-mannosyltransferase activity	Catalysis of the transfer of one or more alpha-D-mannose residues from GDP-mannose to positions 2,6 and others in 1-phosphatidyl-myo-inositol.	tmpzr1t_l9r_go_relaxed.owl	phosphatidyl-myo-inositol alpha-mannosyltransferase activity|guanosine diphosphomannose-phosphatidyl-inositol alpha-mannosyltransferase activity|GDP mannose-phosphatidyl-myo-inositol alpha-mannosyltransferase activity|GDP mannose:1-phosphatidyl-myo-inositol alpha-D-mannosyltransferase activity|GDP-mannose:1-phosphatidyl-1D-myo-inositol alpha-D-mannosyltransferase activity|GDPmannose:1-phosphatidyl-myo-inositol alpha-D-mannosyltransferase activity				RHEA:47368|EC:2.4.1.345|MetaCyc:2.4.1.57-RXN									molecular_function											owl:Class	
GO:0002502	biolink:NamedThing	peptide antigen assembly with MHC class I protein complex	The binding of a peptide to the antigen binding groove of an MHC class I protein complex. Class I here refers to classical class I molecules.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0140566	biolink:NamedThing	epigenetic reader	A transcription regulator that recognizes epigenetic marks such as methylated cytosines in CpG islands and modified histones, and modulates the accessibility of cis-regulatory regions to the transcription machinery.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/20551|https://github.com/geneontology/go-ontology/issues/22136						pg	2020-12-11T13:25:49Z					molecular_function											owl:Class	
GO:0033016	biolink:NamedThing	rhoptry membrane	The lipid bilayer surrounding a rhoptry.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0031583	biolink:NamedThing	phospholipase D-activating G protein-coupled receptor signaling pathway	The series of molecular signals generated as a consequence of a G protein-coupled receptor binding to its physiological ligand, where the pathway proceeds with activation of phospholipase D (PLD) and a subsequent increase in cellular levels of phosphatidic acid (PA).	tmpzr1t_l9r_go_relaxed.owl	phospholipase D-activating G-protein coupled receptor signaling pathway|activation of phospholipase D activity by G-protein coupled receptor protein signaling pathway|G-protein signalling, phospholipase D activating pathway					This term is intended to cover steps in a GPCR signaling pathway both upstream and downstream of phospholipase D (PLD) activation.								biological_process											owl:Class	
GO:0008960	biolink:NamedThing	phosphatidylglycerol-membrane-oligosaccharide glycerophosphotransferase activity	Catalysis of the reaction: phosphatidylglycerol + membrane-derived-oligosaccharide D-glucose = 1,2-diacyl-sn-glycerol + membrane-derived-oligosaccharide 6-(glycerophospho)-D-glucose.	tmpzr1t_l9r_go_relaxed.owl	phosphoglycerol transferase I|phosphatidylglycerol:membrane-derived-oligosaccharide-D-glucose glycerophosphotransferase activity|phosphoglycerol transferase activity|oligosaccharide glycerophosphotransferase activity				MetaCyc:PGLYCEROLTRANSI-RXN|EC:2.7.8.20									molecular_function											owl:Class	
GO:0032992	biolink:NamedThing	protein-carbohydrate complex	A macromolecular complex containing separate protein and carbohydrate molecules.  Separate in this context means not covalently bound to each other.	tmpzr1t_l9r_go_relaxed.owl						Macromolecular complexes in which the carbohydrate component is all covalently bound to protein are not considered protein carbohydrate complexes.								cellular_component											owl:Class	
GO:0031216	biolink:NamedThing	neopullulanase activity	Catalysis of the hydrolysis of pullulan to panose (6-alpha-D-glucosylmaltose).	tmpzr1t_l9r_go_relaxed.owl	pullulanase II activity|pullulan 4-D-glucanohydrolase (panose-forming)				EC:3.2.1.135|MetaCyc:3.2.1.135-RXN									molecular_function											owl:Class	
GO:0060598	biolink:NamedThing	dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis	The process in which the terminal end of a mammary duct bifurcates.	tmpzr1t_l9r_go_relaxed.owl	primary mammary duct branching							dph	2009-05-13T12:16:29Z					biological_process											owl:Class	
GO:0046980	biolink:NamedThing	tapasin binding	Binding to tapasin, a member of the MHC class I loading complex which bridges the TAP peptide transporter to class I molecules.	tmpzr1t_l9r_go_relaxed.owl	TAPBP binding|TAP binding protein binding													molecular_function											owl:Class	
GO:0018666	biolink:NamedThing	2,4-dichlorophenol 6-monooxygenase activity	Catalysis of the reaction: 2,4-dichlorophenol + NADPH + H+ + O2 = 3,5-dichlorocatechol + NADP+ + H2O.	tmpzr1t_l9r_go_relaxed.owl	2,4-dichlorophenol hydroxylase activity|2,4-dichlorophenol monooxygenase activity|2,4-dichlorophenol,NADPH:oxygen oxidoreductase (6-hydroxylating)				RHEA:20920|EC:1.14.13.20|UM-BBD_enzymeID:e0152|MetaCyc:24-DICHLOROPHENOL-6-MONOOXYGENASE-RXN									molecular_function											owl:Class	
GO:0050043	biolink:NamedThing	lactate racemase activity	Catalysis of the reaction: (S)-lactate = (R)-lactate.	tmpzr1t_l9r_go_relaxed.owl	lacticoracemase activity|hydroxyacid racemase activity|lactic acid racemase activity				EC:5.1.2.1|MetaCyc:LACTATE-RACEMASE-RXN|RHEA:10960|KEGG_REACTION:R01450									molecular_function											owl:Class	
GO:0050288	biolink:NamedThing	sorbose dehydrogenase activity	Catalysis of the reaction: L-sorbose + A = 5-dehydro-D-fructose + AH(2).	tmpzr1t_l9r_go_relaxed.owl	L-sorbose:(acceptor) 5-oxidoreductase activity|L-sorbose:acceptor 5-oxidoreductase activity				RHEA:14713|EC:1.1.99.12|KEGG_REACTION:R01696|MetaCyc:SORBOSE-DEHYDROGENASE-RXN									molecular_function											owl:Class	
GO:0017129	biolink:NamedThing	triglyceride binding	Binding to a triester of glycerol.	tmpzr1t_l9r_go_relaxed.owl	triacylglycerol binding													molecular_function											owl:Class	
GO:0098568	biolink:NamedThing	external side of mycolate outer membrane	The side (leaflet) of the mycolate outer membrane that faces the environment and any proteins embedded in it or loosely bound to its surface.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0044100	biolink:NamedThing	sporoplasm	The complex infective apparatus corresponding to the central mass of cytoplasm within a spore that is injected into a host cell by various parasitic microorganisms.	tmpzr1t_l9r_go_relaxed.owl								jl	2009-06-09T03:27:03Z					cellular_component											owl:Class	
GO:0006149	biolink:NamedThing	deoxyinosine catabolic process	The chemical reactions and pathways resulting in the breakdown of deoxyinosine, hypoxanthine deoxyriboside.	tmpzr1t_l9r_go_relaxed.owl	deoxyinosine catabolism|deoxyinosine degradation|deoxyinosine breakdown													biological_process											owl:Class	
GO:0009030	biolink:NamedThing	thiamine-phosphate kinase activity	Catalysis of the reaction: ATP + thiamine phosphate = ADP + H(+) + thiamine diphosphate.	tmpzr1t_l9r_go_relaxed.owl	thiamin monophosphatase activity|ATP:thiamine-phosphate phosphotransferase activity|thiamin-monophosphate kinase activity|thiamin-phosphate kinase activity|thiamine-monophosphate kinase activity|thiamin monophosphokinase activity|thiamin phosphate kinase activity				KEGG_REACTION:R00617|RHEA:15913|MetaCyc:THI-P-KIN-RXN|EC:2.7.4.16									molecular_function											owl:Class	
GO:0097139	biolink:NamedThing	BID-BCL-2 complex	A heterodimeric protein complex consisting of BID and BCL-2, members of the Bcl-2 family of anti- and proapoptotic regulators.	tmpzr1t_l9r_go_relaxed.owl								pr	2011-08-02T01:40:31Z					cellular_component											owl:Class	
GO:0034539	biolink:NamedThing	3,3',5,5'-tetrabromobisphenol A reductive dehalogenase activity	Catalysis of the reaction: 3,3',5,5'-tetrabromobisphenol A + 2 H+ + 2 e- = 3,3',5-tribromobisphenol A + HBr.	tmpzr1t_l9r_go_relaxed.owl					EC:1.97.1.-|UM-BBD_reactionID:r0821									molecular_function											owl:Class	
GO:1902351	biolink:NamedThing	response to imidacloprid	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an imidacloprid stimulus.	tmpzr1t_l9r_go_relaxed.owl								kmv	2013-08-13T19:33:15Z					biological_process											owl:Class	
GO:0042247	biolink:NamedThing	establishment of planar polarity of follicular epithelium	Coordinated organization of groups of cells in the plane of a follicular epithelium, such that they all orient to similar coordinates.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0097146	biolink:NamedThing	NOXA-BCL-xl complex	A heterodimeric protein complex consisting of NOXA and BCL-xl, members of the Bcl-2 family of anti- and proapoptotic regulators.	tmpzr1t_l9r_go_relaxed.owl								pr	2011-08-02T01:49:00Z					cellular_component											owl:Class	
GO:0030737	biolink:NamedThing	iodophenol O-methyltransferase activity	Catalysis of the reaction: 2-iodophenol + S-adenosyl-L-methionine = 1-iodo-2-methoxybenzene + S-adenosyl-L-homocysteine + H(+).	tmpzr1t_l9r_go_relaxed.owl	S-adenosyl-L-methionine:2-iodophenol O-methyltransferase activity				RHEA:14313|MetaCyc:IODOPHENOL-O-METHYLTRANSFERASE-RXN|EC:2.1.1.26|KEGG_REACTION:R03746									molecular_function											owl:Class	
GO:0044847	biolink:NamedThing	iron acquisition from host	The process by which a symbiont acquires iron from its host, either from heme or other iron containing molecules such as transferrin and lactoferrin. Begins with either the secretion of symbiont gene products that bind iron- or heme-containing molecules (siderophores and hemophores) from the symbiont cell into the host, or by expression of receptors that bind iron- or heme-containing molecules on the symbiont cell surface. Ends when the iron-containing compound is transported into the symbiont cell.	tmpzr1t_l9r_go_relaxed.owl	iron acquisition|iron acquisition by symbiont from host heme|iron acquisition by symbiont from host|acquisition by symbiont of nutrients from host via siderophores|acquisition by organism of nutrients from host via siderophores|heme acquisition	https://github.com/geneontology/go-ontology/issues/17896						jl	2014-05-13T13:40:59Z			GO:0052099		biological_process											owl:Class	
GO:1902482	biolink:NamedThing	regulatory T cell apoptotic process	Any apoptotic process in a regulatory T cell.	tmpzr1t_l9r_go_relaxed.owl	regulatory T lymphocyte apoptosis|regulatory T-cell apoptosis|regulatory T lymphocyte apoptotic process|regulatory T cell apoptosis|regulatory T-lymphocyte apoptotic process|regulatory T-cell apoptotic process|regulatory T-lymphocyte apoptosis							nhn	2013-11-04T17:18:09Z					biological_process											owl:Class	
GO:0047287	biolink:NamedThing	lactosylceramide alpha-2,6-N-sialyltransferase activity	Catalysis of the reaction: cytolipin-H + CMP-N-acetylneuraminate = alpha-N-acetylneuraminyl-2,6-beta-galactosyl-1,4-beta-D-glucosylceramide + CMP.	tmpzr1t_l9r_go_relaxed.owl	CMP-sialic acid:lactosylceramide sialyltransferase activity|CMP-N-acetylneuraminic acid:lactosylceramide sialyltransferase activity|cytidine monophosphoacetylneuraminate-lactosylceramide sialyltransferase|CMP-acetylneuraminate-lactosylceramide-sialyltransferase|CMP-N-acetylneuraminate:lactosylceramide alpha-2,6-N-acetylneuraminyltransferase activity				MetaCyc:2.4.99.11-RXN|EC:2.4.99.11|RHEA:21552									molecular_function											owl:Class	
GO:0050408	biolink:NamedThing	[pyruvate kinase]-phosphatase activity	Catalysis of the reaction: [pyruvate kinase] phosphate + H2O = [pyruvate kinase] + phosphate.	tmpzr1t_l9r_go_relaxed.owl	ATP:pyruvate 2-O-phosphotransferase-phosphate phosphohydrolase activity|pyruvate kinase phosphatase activity|pyruvate kinase-phosphatase activity				EC:3.1.3.49|MetaCyc:PYRUVATE-KINASE-PHOSPHATASE-RXN									molecular_function											owl:Class	
GO:0047039	biolink:NamedThing	tetrahydroxynaphthalene reductase activity	Catalysis of the reaction: NADP+ + scytalone = NADPH + H+ + 1,3,6,8-naphthalenetetrol.	tmpzr1t_l9r_go_relaxed.owl	T4HN reductase activity|scytalone:NADP+ delta5-oxidoreductase activity				RHEA:21908|EC:1.1.1.252|MetaCyc:1.1.1.252-RXN									molecular_function											owl:Class	
GO:0004320	biolink:NamedThing	oleoyl-[acyl-carrier-protein] hydrolase activity	Catalysis of the reaction: oleoyl-[acyl-carrier protein] + H2O = [acyl-carrier protein] + oleate.	tmpzr1t_l9r_go_relaxed.owl	oleoyl-acyl-carrier-protein hydrolase|oleoyl-ACP hydrolase activity|oleoyl-ACP thioesterase activity|oleoyl-[acyl-carrier protein] hydrolase activity|oleoyl-acyl carrier protein thioesterase activity				MetaCyc:PWY-5142|MetaCyc:3.1.2.14-RXN|RHEA:15057|EC:3.1.2.14									molecular_function											owl:Class	
GO:0043779	biolink:NamedThing	cobalt-precorrin-5A acetaldehyde-lyase activity	Catalysis of the reaction: cobalt-precorrin 5A + H2O = cobalt-precorrin 5B + acetaldehyde.	tmpzr1t_l9r_go_relaxed.owl	cobalt-precorrin 5A acetaldehyde-lyase activity				RHEA:26281|MetaCyc:RXN-8763									molecular_function											owl:Class	
GO:0099526	biolink:NamedThing	presynapse to nucleus signaling pathway	A series of molecular signals that conveys information from the presynapse to the nucleus via cytoskeletal transport of a protein from a presynapse to the component to the nucleus where it affects biochemical processes that occur in the nucleus (e.g DNA transcription, mRNA splicing, or DNA/histone modifications).	tmpzr1t_l9r_go_relaxed.owl	presynaptic signaling to nucleus					This class does not cover the cellular machinery (motor proteins, cargo-recognition proteins) that transports the signaling protein along the cytoskeleton towards the nucleus. For these cases, annotate to the appropriate transport/trafficking term.								biological_process											owl:Class	
GO:0052812	biolink:NamedThing	phosphatidylinositol-3,4-bisphosphate 5-kinase activity	Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 3,4-bisphosphate + ATP = a 1-phosphatidyl-1D-myo-inositol 3,4,5-trisphosphate + ADP + 2 H(+).	tmpzr1t_l9r_go_relaxed.owl	ATP:1-phosphatidyl-1D-myo-inositol-3,4-bisphosphate 5-phosphotransferase activity				EC:2.7.1.153|Reactome:R-HSA-1675773			ai	2011-10-21T03:52:02Z					molecular_function											owl:Class	
GO:0031807	biolink:NamedThing	H1 histamine receptor binding	Binding to a H1 histamine receptor.	tmpzr1t_l9r_go_relaxed.owl	H1 histamine receptor ligand													molecular_function											owl:Class	
GO:0072669	biolink:NamedThing	tRNA-splicing ligase complex	A protein complex that catalyzes the ligation of cleaved pre-tRNAs by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester.	tmpzr1t_l9r_go_relaxed.owl	tRNA splicing ligase complex				MetaCyc:ENTMULTI-CPLX			mah	2011-02-18T10:55:26Z					cellular_component											owl:Class	
GO:0047245	biolink:NamedThing	N-acetylglucosaminyldiphosphoundecaprenol glucosyltransferase activity	Catalysis of the reaction: N-acetyl-D-glucosaminyldiphosphoundecaprenol + UDP-D-glucose = beta-D-glucosyl-1,4-N-acetyl-D-glucosaminyldiphosphoundecaprenol + UDP.	tmpzr1t_l9r_go_relaxed.owl	uridine diphosphoglucose-acetylglucosaminylpyrophosphorylundecaprenol glucosyltransferase activity|UDPglucose:N-acetyl-D-glucosaminyldiphosphoundecaprenol 4-beta-D-glucosyltransferase activity|UDP-D-glucose:N-acetylglucosaminyl pyrophosphorylundecaprenol glucosyltransferase activity|UDP-glucose:N-acetyl-D-glucosaminyldiphosphoundecaprenol 4-beta-D-glucosyltransferase activity				RHEA:20952|MetaCyc:2.4.1.188-RXN|EC:2.4.1.188									molecular_function											owl:Class	
GO:0045340	biolink:NamedThing	mercury ion binding	Binding to a mercury ion (Hg).	tmpzr1t_l9r_go_relaxed.owl	mercury binding|Hg ion binding													molecular_function											owl:Class	
GO:0033736	biolink:NamedThing	L-lysine 6-oxidase activity	Catalysis of the reaction: L-lysine + H(2)O + O(2) = allysine + H(2)O(2) + NH(4)(+).	tmpzr1t_l9r_go_relaxed.owl	L-lysine:oxygen 6-oxidoreductase (deaminating) activity|Lod|marinocine|L-lysine-epsilon-oxidase activity|LodA				KEGG_REACTION:R07598|RHEA:22548|EC:1.4.3.20|MetaCyc:1.4.3.20-RXN									molecular_function											owl:Class	
GO:0097174	biolink:NamedThing	1,6-anhydro-N-acetyl-beta-muramic acid metabolic process	The chemical reactions and pathways involving 1,6-anhydro-N-acetyl-beta-muramic acid, the 1,6-anhydro-derivative of N-acetyl-beta-muramic acid.	tmpzr1t_l9r_go_relaxed.owl	1,6-anhydro-N-acetylmuramic acid metabolic process|1,6-anhydro-N-acetyl-beta-muramic acid metabolism|1,6-anhydro-N-acetyl-beta-muramate metabolism|1,6-anhydro-N-acetylmuramic acid metabolism|1,6-anhydro-N-acetyl-beta-muramate metabolic process							pr	2011-10-07T12:54:36Z					biological_process											owl:Class	
GO:0047390	biolink:NamedThing	glycerophosphocholine cholinephosphodiesterase activity	Catalysis of the reaction: sn-glycero-3-phosphocholine + H(2)O = choline phosphate + glycerol + H(+).	tmpzr1t_l9r_go_relaxed.owl	sn-glycero-3-phosphocholine cholinephosphohydrolase activity|L-3-glycerylphosphinicocholine cholinephosphohydrolase activity				EC:3.1.4.38|KEGG_REACTION:R02591|Reactome:R-HSA-6814797|RHEA:19545|MetaCyc:3.1.4.38-RXN									molecular_function											owl:Class	
GO:0051365	biolink:NamedThing	cellular response to potassium ion starvation	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of potassium ions.	tmpzr1t_l9r_go_relaxed.owl	cellular response to potassium ion deprivation|cellular response to K+ ion deprivation|cellular response to K+ ion starvation|cellular response to potassium starvation													biological_process											owl:Class	
GO:0003908	biolink:NamedThing	methylated-DNA-[protein]-cysteine S-methyltransferase activity	Catalysis of the reaction: DNA (containing 6-O-methylguanine) + (protein)-L-cysteine = DNA (without 6-O-methylguanine) + protein S-methyl-L-cysteine.	tmpzr1t_l9r_go_relaxed.owl	6-O-methylguanine-DNA methyltransferase activity|O6-alkylguanine-DNA alkyltransferase|MGMT|DNA-6-O-methylguanine:[protein]-L-cysteine S-methyltransferase activity|DNA-6-O-methylguanine:protein-L-cysteine S-methyltransferase activity|O-6-methylguanine-DNA-alkyltransferase activity|methylated-DNA-protein-cysteine S-methyltransferase activity				Reactome:R-HSA-73892|EC:2.1.1.63|MetaCyc:2.1.1.63-RXN|RHEA:24000									molecular_function											owl:Class	
GO:0018059	biolink:NamedThing	N-terminal peptidyl-serine deamination	The oxidative deamination of N-terminal peptidyl-serine to form pyruvic acid with an amide bond between its 1-carboxyl group and the N-terminal residue.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0048038	biolink:NamedThing	quinone binding	Binding to a quinone, any member of a class of diketones derivable from aromatic compounds by conversion of two CH groups into CO groups with any necessary rearrangement of double bonds.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0102130	biolink:NamedThing	malonyl-CoA methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine  + a malonyl-[acp] = S-adenosyl-L-homocysteine  + a malonyl-[acp] methyl ester.	tmpzr1t_l9r_go_relaxed.owl					RHEA:17105|MetaCyc:RXN-11475|EC:2.1.1.197									molecular_function											owl:Class	
GO:0035005	biolink:NamedThing	1-phosphatidylinositol-4-phosphate 3-kinase activity	Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 4-phosphate + ATP = 1-phosphatidyl-1D-myo-inositol 3,4-bisphosphate + ADP + 2 H(+).	tmpzr1t_l9r_go_relaxed.owl	C2-domain-containing phosphoinositide 3-kinase activity|phosphatidylinositol 3-kinase activity, class II|ATP:1-phosphatidyl-1D-myo-inositol-4-phosphate 3-phosphotransferase activity|phosphatidylinositol 3-kinase activity, class I|type II phosphoinositide 3-kinase activity|phosphatidylinositol-4-phosphate 3-kinase activity|phosphatidylinositol 3-kinase, class I, catalyst activity				Reactome:R-HSA-1675928|KEGG_REACTION:R05795|Reactome:R-HSA-8868072|EC:2.7.1.154|Reactome:R-HSA-1676206|RHEA:18373|MetaCyc:2.7.1.154-RXN|Reactome:R-HSA-1676109									molecular_function											owl:Class	
GO:0047658	biolink:NamedThing	alpha-amino-acid esterase activity	Catalysis of the reaction: an alpha-amino acid ester + H2O = an alpha-amino acid + an alcohol.	tmpzr1t_l9r_go_relaxed.owl	a-amino-acid esterase activity|alpha-amino-acid ester hydrolase activity|alpha-amino-acid-ester aminoacylhydrolase activity|alpha-amino acid ester hydrolase activity				Reactome:R-HSA-6784959|RHEA:17241|EC:3.1.1.43|MetaCyc:ALPHA-AMINO-ACID-ESTERASE-RXN									molecular_function											owl:Class	
GO:0051850	biolink:NamedThing	acquisition of nutrients from symbiont	The production of structures and/or molecules in an organism that are required for the acquisition and/or utilization of nutrients obtained from its symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0070742	biolink:NamedThing	C2H2 zinc finger domain binding	Binding to a C2H2-type zinc finger domain of a protein. The C2H2 zinc finger is the classical zinc finger domain, in which two conserved cysteines and histidines co-ordinate a zinc ion.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-06-23T11:26:02Z					molecular_function											owl:Class	
GO:0033051	biolink:NamedThing	aminophosphonate metabolic process	The chemical reactions and pathways involving aminophosphonates, phosphonic acid derivatives that contain an amino group.	tmpzr1t_l9r_go_relaxed.owl	aminophosphonate metabolism				KEGG_PATHWAY:map00440									biological_process											owl:Class	
GO:0061304	biolink:NamedThing	retinal blood vessel morphogenesis	The process whose specific outcome is the progression of a blood vessel of the retina over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-09-16T09:02:59Z					biological_process											owl:Class	
GO:1905238	biolink:NamedThing	cellular response to cyclosporin A	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cyclosporin A stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to cyclophilin							sl	2016-06-07T21:32:14Z					biological_process											owl:Class	
GO:0032598	biolink:NamedThing	B cell receptor transport into immunological synapse	The directed movement of a B cell receptor into an immunological synapse.	tmpzr1t_l9r_go_relaxed.owl	BCR transport into immunological synapse|BCR translocation into immunological synapse|B cell receptor translocation into immunological synapse													biological_process											owl:Class	
GO:0106309	biolink:NamedThing	progesterone 21-hydroxylase activity	Catalysis of the reaction: O2 + progesterone + reduced [NADPH--hemoprotein reductase] = 21-hydroxyprogesterone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase].	tmpzr1t_l9r_go_relaxed.owl					RHEA:50304			hjd	2020-09-21T14:40:30Z					molecular_function											owl:Class	
GO:0052430	biolink:NamedThing	modulation by host of symbiont RNA levels	The alteration by an organism of the levels of RNA in a symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0062245	biolink:NamedThing	double membrane vesicle viral factory inner membrane	The inner of the two endoplasmic reticulum-derived lipid bilayer membranes that bound a double membrane vesicle viral factory.	tmpzr1t_l9r_go_relaxed.owl	inner membrane of double membrane vesicle viral factory							dph	2020-04-20T20:55:49Z					cellular_component											owl:Class	
GO:0080048	biolink:NamedThing	GDP-D-glucose phosphorylase activity	Catalysis of the reaction: GDP-D-glucose + phosphate = D-glucose-1-P + GDP.	tmpzr1t_l9r_go_relaxed.owl					RHEA:30387|EC:2.7.7.78|MetaCyc:RXN-12486									molecular_function											owl:Class	
GO:0071080	biolink:NamedThing	alpha3-beta1 integrin-basigin complex	A protein complex that consists of an alpha3-beta1 integrin complex bound to the cell surface protein basigin.	tmpzr1t_l9r_go_relaxed.owl	ITGA3-ITGB1-BSG complex							mah	2009-11-06T04:43:26Z					cellular_component											owl:Class	
GO:1990313	biolink:NamedThing	type-III cohesin domain binding	Binding to a type-III cohesin domain of a protein. Type-III cohesin domain is the binding partner of type-III dockerin domain.	tmpzr1t_l9r_go_relaxed.owl								tt	2014-03-07T04:58:07Z					molecular_function											owl:Class	
GO:0042988	biolink:NamedThing	X11-like protein binding	Binding to X11-like protein, a neuron-specific adaptor protein.	tmpzr1t_l9r_go_relaxed.owl	X11L binding													molecular_function											owl:Class	
GO:0062144	biolink:NamedThing	L-propargylglycine synthase activity	Catalysis of the reaction: L-2-amino-4-chloropent-4-enoate = chloride + H(+) + L-propargylglycine.	tmpzr1t_l9r_go_relaxed.owl					RHEA:59892			dph	2019-09-02T16:48:52Z					molecular_function											owl:Class	
GO:0030015	biolink:NamedThing	CCR4-NOT core complex	The core of the CCR4-NOT complex. In Saccharomyces the CCR4-NOT core complex comprises Ccr4p, Caf1p, Caf40p, Caf130p, Not1p, Not2p, Not3p, Not4p, and Not5p.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0003735	biolink:NamedThing	structural constituent of ribosome	The action of a molecule that contributes to the structural integrity of the ribosome.	tmpzr1t_l9r_go_relaxed.owl	ribosomal RNA|ribosomal protein					Note that this term may be used to annotate ribosomal RNAs as well as ribosomal proteins.						GO:0003741|GO:0003736|GO:0003739|GO:0003738|GO:0003742|GO:0003737|GO:0003740		molecular_function											owl:Class	
GO:0017005	biolink:NamedThing	3'-tyrosyl-DNA phosphodiesterase activity	Catalysis of the hydrolysis of 3'-phosphotyrosyl groups formed as covalent intermediates (in DNA backbone breakage) between DNA topoisomerase I and DNA.	tmpzr1t_l9r_go_relaxed.owl						See also the molecular function term 'DNA topoisomerase type I activity ; GO:0003917'.								molecular_function											owl:Class	
GO:0061521	biolink:NamedThing	hepatic stellate cell differentiation	The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a hepatic stellate cell.	tmpzr1t_l9r_go_relaxed.owl								dph	2013-04-18T13:36:08Z					biological_process											owl:Class	
GO:0016767	biolink:NamedThing	geranylgeranyl-diphosphate geranylgeranyltransferase activity	Catalysis of the reaction: 2 geranylgeranyl diphosphate = diphosphate + prephytoene diphosphate.	tmpzr1t_l9r_go_relaxed.owl	geranylgeranyl-diphosphate:geranylgeranyl-diphosphate geranylgeranyltransferase activity|prephytoene-diphosphate synthase activity|phytoene synthetase activity|PSase activity				MetaCyc:2.5.1.32-RXN|EC:2.5.1.32|RHEA:22296									molecular_function											owl:Class	
GO:0140438	biolink:NamedThing	protein stearoylation	The covalent attachment of a stearoyl group to an amino acid in a protein.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/18882						pg	2020-03-11T07:54:48Z					biological_process											owl:Class	
GO:1990208	biolink:NamedThing	positive regulation by symbiont of RNA levels in host	Any process in which an organism activates, maintains or increases the frequency, rate or extent of the RNA levels in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl								ml	2013-10-08T13:31:41Z					biological_process											owl:Class	
GO:0046771	biolink:NamedThing	viral budding from inner nuclear membrane	The envelopment of a virus, in which the nucleocapsid evaginates from the host inner nuclear membrane system into the perinuclear space, thus acquiring a membrane envelope.	tmpzr1t_l9r_go_relaxed.owl	virus budding from inner nuclear membrane by viral capsid envelopment|inner nuclear membrane viral budding during viral capsid envelopment|viral budding from inner nuclear membrane during viral capsid envelopment|viral budding from inner nuclear membrane by viral capsid envelopment|virus budding from inner nuclear membrane during viral capsid envelopment	https://github.com/geneontology/go-ontology/issues/20782												biological_process											owl:Class	
GO:0047335	biolink:NamedThing	3-phosphoglyceroyl-phosphate-polyphosphate phosphotransferase activity	Catalysis of the reaction: long-chain-polyphosphate + 3-phospho-D-glyceroyl-phosphate = long-chain-polyphosphate + 3-phosphoglycerate.	tmpzr1t_l9r_go_relaxed.owl	1,3-diphosphoglycerate-polyphosphate phosphotransferase activity|diphosphoglycerate-polyphosphate phosphotransferase activity|3-phospho-D-glyceroyl-phosphate:polyphosphate phosphotransferase activity				EC:2.7.4.17|RHEA:18665|MetaCyc:2.7.4.17-RXN									molecular_function											owl:Class	
GO:0015475	biolink:NamedThing	adhesin autotransporter activity	Enables the transfer of adhesin from the periplasm to the external milieu; the adhesin and the porin are the N- and C-terminal regions of the same protein, respectively.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1990478	biolink:NamedThing	response to ultrasound	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ultrasonic stimulus.	tmpzr1t_l9r_go_relaxed.owl								sl	2014-09-09T22:11:32Z					biological_process											owl:Class	
GO:0055089	biolink:NamedThing	fatty acid homeostasis	Any process involved in the maintenance of an internal steady state of fatty acid within an organism or cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0102654	biolink:NamedThing	1-18:1-2-16:0-phosphatidylglycerol trans-3 desaturase activity	Catalysis of the reaction: 1-[(9Z)-octadec-9-enoyl]-2-hexadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol)(1-) + O2 + a reduced electron acceptor <=> 1-18:1-2-trans-16:1-phosphatidylglycerol + 2 H2O + an oxidized electron acceptor.	tmpzr1t_l9r_go_relaxed.owl					EC:1.14.19.43|MetaCyc:RXN-1725|RHEA:46764									molecular_function											owl:Class	
GO:0006678	biolink:NamedThing	glucosylceramide metabolic process	The chemical reactions and pathways involving glucosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of glucose by a ceramide group. They are neutral glycolipids containing equimolar amounts of fatty acid, glucose, and sphingosine or a sphingosine derivative.	tmpzr1t_l9r_go_relaxed.owl	glucosylceramide metabolism													biological_process											owl:Class	
GO:0010136	biolink:NamedThing	ureide catabolic process	The chemical reactions and pathways resulting in the breakdown of ureide, which is the organic form of nitrogen in nitrogen fixing and transporting plants with the release of ammonium.	tmpzr1t_l9r_go_relaxed.owl	ureide breakdown|ureide degradation|ureide catabolism				MetaCyc:URDEGR-PWY									biological_process											owl:Class	
GO:0102163	biolink:NamedThing	3-hydroxyacyl-CoA-acyl carrier protein transferase activity	Catalysis of the reaction: coenzyme A + a (3R)-3-hydroxyacyl-[acyl-carrier protein] = a (3R)-3-hydroxyacyl-CoA + a holo-[acyl-carrier protein].	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-11785									molecular_function											owl:Class	
GO:0032190	biolink:NamedThing	acrosin binding	Binding to acrosin, a protein that is found in the acrosomes of sperm and possesses protease and carbohydrate binding activities.	tmpzr1t_l9r_go_relaxed.owl	acrosin light chain binding|acrosin heavy chain binding											GO:0032192|GO:0032191		molecular_function											owl:Class	
GO:0120239	biolink:NamedThing	vascular endothelial glycocalyx	The carbohydrate-rich layer lining the vascular endothelium connected to the endothelium through a variety of molecules, mainly proteoglycans and glycoproteins. These form a network in which soluble molecules, either plasma- or endothelium-derived, are incorporated.	tmpzr1t_l9r_go_relaxed.owl	endothelial glycocalyx	https://github.com/geneontology/go-ontology/issues/19782						krc	2020-07-27T21:55:41Z					cellular_component											owl:Class	
GO:0098017	biolink:NamedThing	viral capsid, major subunit	The part of the viral capsid that comprises the most common capsomere type. For example, in a T=3 icosahedral capsid, which is composed of 12 pentameric and 20 hexameric capsomeres, the hexameric capsomeres are major subunits.	tmpzr1t_l9r_go_relaxed.owl	major head protein|major capsomere							bm	2012-07-19T11:21:21Z					cellular_component											owl:Class	
GO:0036448	biolink:NamedThing	cellular response to glucose-phosphate stress	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the accumulation of glucose-phosphate.	tmpzr1t_l9r_go_relaxed.owl								bf	2013-10-31T11:20:08Z					biological_process											owl:Class	
GO:0033354	biolink:NamedThing	chlorophyll cycle	A cyclic series of interconversions involving chlorophyll a, chlorophyll b and several chlorophyllide intermediates.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:PWY-5068									biological_process											owl:Class	
GO:0019451	biolink:NamedThing	L-cysteine catabolic process to pyruvate, using cysteine dioxygenase	The chemical reactions and pathways resulting in the breakdown into pyruvate of L-cystine, catalyzed by the enzyme cysteine dioxygenase (EC:1.13.11.20).	tmpzr1t_l9r_go_relaxed.owl	L-cysteine degradation to pyruvate, using cysteine dioxygenase|L-cysteine breakdown to pyruvate, using cysteine dioxygenase				MetaCyc:CYSTEINE-DEG-PWY									biological_process											owl:Class	
GO:0044519	biolink:NamedThing	envenomation resulting in modulation of vasoactive intestinal polypeptide receptor activity in other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant modulation of the activity of a vasoactive intestinal polypeptide receptor in the bitten organism.	tmpzr1t_l9r_go_relaxed.owl	envenomation resulting in regulation of VIP receptor activity in other organism|envenomation resulting in modulation of VIP receptor activity in other organism|envenomation resulting in regulation of vasoactive intestinal polypeptide receptor activity in other organism							jl	2012-02-26T11:53:33Z					biological_process											owl:Class	
GO:0033142	biolink:NamedThing	progesterone receptor binding	Binding to a progesterone receptor.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0030767	biolink:NamedThing	3-hydroxyanthranilate 4-C-methyltransferase activity	Catalysis of the reaction: 3-hydroxyanthranilate + S-adenosyl-L-methionine = 3-hydroxy-4-methylanthranilate + S-adenosyl-L-homocysteine + H(+).	tmpzr1t_l9r_go_relaxed.owl	S-adenosyl-L-methionine:3-hydroxyanthranilate 4-C-methyltransferase activity|3-hydroxyanthranilate 4-methyltransferase activity				RHEA:17833|MetaCyc:2.1.1.97-RXN|KEGG_REACTION:R02667|EC:2.1.1.97									molecular_function											owl:Class	
GO:0035512	biolink:NamedThing	hydrolytic DNA demethylation	The hydrolytic removal of the methyl group from one or more nucleotides within a DNA molecule.	tmpzr1t_l9r_go_relaxed.owl								bf	2010-04-30T02:24:21Z					biological_process											owl:Class	
GO:0043897	biolink:NamedThing	glucan 1,4-alpha-maltohydrolase activity	Catalysis of the hydrolysis of (1->4)-alpha-D-glucosidic linkages in polysaccharides so as to remove successive alpha-maltose residues from the non-reducing ends of the chains.	tmpzr1t_l9r_go_relaxed.owl	maltogenic alpha-amylase activity|1,4-alpha-D-glucan alpha-maltohydrolase activity|glucan-1,4-alpha-maltohydrolase activity				MetaCyc:3.2.1.133-RXN|EC:3.2.1.133									molecular_function											owl:Class	
GO:0102670	biolink:NamedThing	2,7,4'-trihydroxyisoflavanone-4'-O-methyltransferase activity	Catalysis of the reaction: 2,4',7-trihydroxyisoflavanone + S-adenosyl-L-methionine  <=> H+ + 2,7-dihydroxy-4'-methoxyisoflavanone + S-adenosyl-L-homocysteine.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-3624|RHEA:31371|EC:2.1.1.212									molecular_function											owl:Class	
GO:0047080	biolink:NamedThing	deoxyuridine 2'-dioxygenase activity	Catalysis of the reaction: 2'-deoxyuridine + 2-oxoglutarate + O(2) = CO(2) + succinate + uridine.	tmpzr1t_l9r_go_relaxed.owl	thymidine 2-oxoglutarate dioxygenase activity|thymidine 2'-dioxygenase activity|thymidine dioxygenase activity|thymidine 2'-hydroxylase activity|pyrimidine-deoxynucleoside 2'-dioxygenase activity|2'-deoxyuridine,2-oxoglutarate:oxygen oxidoreductase (2'-hydroxylating)|deoxyuridine 2'-hydroxylase activity|pyrimidine-deoxynucleoside,2-oxoglutarate 2'-dioxygenase activity|pyrimidine deoxyribonucleoside 2'-hydroxylase activity				KEGG_REACTION:R01879|MetaCyc:1.14.11.3-RXN|RHEA:21076|EC:1.14.11.3									molecular_function											owl:Class	
GO:0070763	biolink:NamedThing	Delta1 complex	A protein complex that consists of homodimer of the Notch ligand Delta1.	tmpzr1t_l9r_go_relaxed.owl	Delta1 homodimer complex							mah	2009-06-29T01:04:12Z					cellular_component											owl:Class	
GO:0103046	biolink:NamedThing	alanylglutamate dipeptidase activity	Catalysis of the reaction: L-alanyl-L-glutamate + H2O <=> L-alanine + L-glutamate.	tmpzr1t_l9r_go_relaxed.owl					EC:3.4.13.18|MetaCyc:RXN0-6981									molecular_function											owl:Class	
GO:0106312	biolink:NamedThing	methylenetetrahydrofolate reductase NADH activity	Catalysis of the reaction: 5-methyltetrahydrofolate + NAD + = 5,10-methylenetetrahydrofolate + NADH + H+.	tmpzr1t_l9r_go_relaxed.owl					RHEA:19821			hjd	2020-09-23T14:20:07Z					molecular_function											owl:Class	
GO:0032920	biolink:NamedThing	putrescine acetylation	The modification of putrescine by addition of acetyl groups.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0031688	biolink:NamedThing	A2B adenosine receptor binding	Binding to an A2B adenosine receptor.	tmpzr1t_l9r_go_relaxed.owl	A2B adenosine receptor ligand													molecular_function											owl:Class	
GO:0102053	biolink:NamedThing	(-)-jasmonoyl-isoleucine synthetase activity	Catalysis of the reaction: (-)-jasmonate + L-isoleucine  + ATP(4-) <=> H+ + (-)-jasmonoyl-L-isoleucine + AMP(2-) + diphosphoric acid.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-10435									molecular_function											owl:Class	
GO:0034421	biolink:NamedThing	post-translational protein acetylation	The addition of an acetyl group to one or more amino acids in a protein, occurring after the protein has been completely translated and released from the ribosome.	tmpzr1t_l9r_go_relaxed.owl	post-translational protein amino acid acetylation|posttranslational protein amino acid acetylation													biological_process											owl:Class	
GO:0004040	biolink:NamedThing	amidase activity	Catalysis of the reaction: a monocarboxylic acid amide + H2O = a monocarboxylate + NH3.	tmpzr1t_l9r_go_relaxed.owl	N-acetylaminohydrolase activity|acylamidase activity|acylase activity|fatty acylamidase activity|amidohydrolase activity|acylamide amidohydrolase activity|acetamidase activity				UM-BBD_enzymeID:e0068|RHEA:12020|EC:3.5.1.4|MetaCyc:AMIDASE-RXN									molecular_function											owl:Class	
GO:0032699	biolink:NamedThing	negative regulation of interleukin-16 production	Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-16 production.	tmpzr1t_l9r_go_relaxed.owl	down regulation of interleukin-16 production|downregulation of interleukin-16 production|down-regulation of interleukin-16 production|inhibition of interleukin-16 production|negative regulation of IL-16 production|negative regulation of interleukin-16 biosynthetic process											GO:0045376		biological_process											owl:Class	
GO:0031874	biolink:NamedThing	type 3 proteinase activated receptor binding	Binding to a type 3 proteinase activated receptor.	tmpzr1t_l9r_go_relaxed.owl	type 3 proteinase activated receptor ligand													molecular_function											owl:Class	
GO:0052880	biolink:NamedThing	oxidoreductase activity, acting on diphenols and related substances as donors, with copper protein as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which a diphenol, or related compound, acts as a hydrogen or electron donor and reduces a copper protein.	tmpzr1t_l9r_go_relaxed.owl					EC:1.10.9.-									molecular_function											owl:Class	
GO:0034084	biolink:NamedThing	steryl deacetylase activity	Catalysis of the hydrolysis of an acetyl group or groups from an acetylated sterol.	tmpzr1t_l9r_go_relaxed.owl	sterol deacetylase activity													molecular_function											owl:Class	
GO:0004059	biolink:NamedThing	aralkylamine N-acetyltransferase activity	Catalysis of the reaction: acetyl-CoA + an aralkylamine = CoA + an N-acetylaralkylamine.	tmpzr1t_l9r_go_relaxed.owl	melatonin rhythm enzyme activity|serotonin acetylase activity|serotonin N-acetyltransferase activity|AANAT activity|serotonin acetyltransferase activity|arylalkylamine N-acetyltransferase activity|acetyl-CoA:2-arylethylamine N-acetyltransferase activity				EC:2.3.1.87|MetaCyc:ARALKYLAMINE-N-ACETYLTRANSFERASE-RXN|Reactome:R-HSA-209792|RHEA:20497									molecular_function											owl:Class	
GO:0016524	biolink:NamedThing	latrotoxin receptor activity	Combining with alpha-latrotoxin, a potent presynaptic neurotoxin, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	latrophilin													molecular_function											owl:Class	
GO:0061711	biolink:NamedThing	N(6)-L-threonylcarbamoyladenine synthase activity	Catalysis of the reaction: L-threonylcarbamoyladenylate + adenine(37) in tRNA = AMP + N(6)-L-threonylcarbamoyladenine(37) in tRNA.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-6784494|EC:2.3.1.234|MetaCyc:RXN-14570|RHEA:37059			dph	2015-06-23T08:34:44Z					molecular_function											owl:Class	
GO:0033773	biolink:NamedThing	isoflavone 2'-hydroxylase activity	Catalysis of the reaction: an isoflavone + O2 + reduced [NADPH-hemoprotein reductase] = a 2'-hydroxyisoflavone + H+ + H2O + oxidized [NADPH-hemoprotein reductase].	tmpzr1t_l9r_go_relaxed.owl	CYP81E1|isoflavone 2'-monooxygenase activity|CYP Ge-3	https://github.com/geneontology/go-ontology/issues/21412			RHEA:18849|MetaCyc:ISOFLAVONE-2-HYDROXYLASE-RXN|EC:1.14.14.90	Formerly EC:1.14.13.89.								molecular_function											owl:Class	
GO:0034848	biolink:NamedThing	naphthyl-2-oxomethyl-succinyl-CoA succinyl transferase activity	Catalysis of the reaction: naphthyl-2-oxomethyl-succinyl-CoA + CoASH = 2-naphthoyl-CoA + succinyl-CoA.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r1261									molecular_function											owl:Class	
GO:0008429	biolink:NamedThing	phosphatidylethanolamine binding	Binding to a phosphatidylethanolamine, a class of glycerophospholipids in which a phosphatidyl group is esterified to the hydroxyl group of ethanolamine.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0042751	biolink:NamedThing	estivation	Any process in which an organism enters and maintains a period of dormancy, similar to hibernation, but that occurs during the summer. It insulates against heat to prevent the harmful effects of the season.	tmpzr1t_l9r_go_relaxed.owl	aestivation				Wikipedia:Estivation									biological_process											owl:Class	
GO:0061100	biolink:NamedThing	lung neuroendocrine cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a neuroendocrine cell of the lung epithelium.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-04-27T03:28:46Z					biological_process											owl:Class	
GO:0090499	biolink:NamedThing	pimelyl-[acyl-carrier protein] methyl ester esterase activity	Catalysis of the reaction: pimelyl-[acyl-carrier protein] methyl ester + H2O = pimelyl-[acyl-carrier protein] + methanol.	tmpzr1t_l9r_go_relaxed.owl	pimelyl-[acyl-carrier protein] methyl ester hydrolase activity					Note that while this reaction occurs on a modified protein (acyl-carrier protein), the ACP only acts as a carrier that later releases the end product.		tb	2012-10-19T12:10:01Z					molecular_function											owl:Class	
GO:1902928	biolink:NamedThing	inulin biosynthetic process	The chemical reactions and pathways resulting in the formation of inulin.	tmpzr1t_l9r_go_relaxed.owl	inulin formation|inulin synthesis|inulin anabolism|inulin biosynthesis					SUC2 in S. cerevisiae strain JZ1C in PMID:23104410.		se	2014-04-21T23:54:51Z					biological_process											owl:Class	
GO:0033988	biolink:NamedThing	bile-acid 7alpha-dehydratase activity	Catalysis of the reaction: 7alpha,12alpha-dihydroxy-3-oxochol-4-en-24-oate = 12alpha-hydroxy-3-oxochola-4,6-dien-24-oate + H(2)O.	tmpzr1t_l9r_go_relaxed.owl	7alpha,12alpha-dihydroxy-3-oxochol-4-enoate hydro-lyase activity|7alpha,12alpha-dihydroxy-3-oxochol-4-enoate hydro-lyase (12alpha-hydroxy-3-oxochola-4,6-dienoate-forming) activity|BA7 alpha dehydratase activity				RHEA:10436|EC:4.2.1.106|MetaCyc:4.2.1.106-RXN|KEGG_REACTION:R07318									molecular_function											owl:Class	
GO:1990444	biolink:NamedThing	F-box domain binding	Binding to an F-box domain of a protein.	tmpzr1t_l9r_go_relaxed.owl								bf	2014-08-05T13:45:14Z					molecular_function											owl:Class	
GO:0072653	biolink:NamedThing	interferon-omega production	The appearance of interferon-omega due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	tmpzr1t_l9r_go_relaxed.owl	IFN-omega production|IFNW production|interferon-omega secretion					Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.						GO:0072654		biological_process											owl:Class	
GO:0060060	biolink:NamedThing	post-embryonic retina morphogenesis in camera-type eye	The process in which the anatomical structure of the retina is generated and organized in a camera-type eye during the post-embryonic life stage.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0043959	biolink:NamedThing	L-erythro-3-methylmalyl-CoA lyase activity	Catalysis of the reaction: propionyl-CoA + glyoxylate = L-erythro-3-methylmalyl-CoA.	tmpzr1t_l9r_go_relaxed.owl	HpcH/HpaI aldolase				EC:4.1.3.24									molecular_function											owl:Class	
GO:0015473	biolink:NamedThing	fimbrial usher porin activity	A porin that acts in the assembly of fimbria together with fimbrial chaperone.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0005292	biolink:NamedThing	high-affinity lysine transmembrane transporter activity	Enables the transfer of lysine from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.	tmpzr1t_l9r_go_relaxed.owl	high affinity lysine transporter activity|high affinity lysine transmembrane transporter activity													molecular_function											owl:Class	
GO:0033190	biolink:NamedThing	solanapyrone synthase activity	Catalysis of the cyclization of double bonds in prosolanapyrone II to form (-)-solanapyrone A.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0042259	biolink:NamedThing	peptidyl-L-beta-methylthioasparagine biosynthetic process from peptidyl-asparagine	The modification of peptidyl-asparagine to form peptidyl-L-beta-methylthioasparagine, typical of bacterial ribosomal protein S12.	tmpzr1t_l9r_go_relaxed.owl	peptidyl-L-beta-methylthioasparagine anabolism from peptidyl-asparagine|peptidyl-L-beta-methylthioasparagine synthesis from peptidyl-asparagine|peptidyl-L-beta-methylthioasparagine formation from peptidyl-asparagine				RESID:AA0320									biological_process											owl:Class	
GO:0018067	biolink:NamedThing	peptidyl-L-3',4'-dihydroxyphenylalanine biosynthetic process from peptidyl-tyrosine	The modification of protein tyrosine to peptidyl-L-3',4'-dihydroxyphenylalanine (DOPA).	tmpzr1t_l9r_go_relaxed.owl	peptidyl-L-3',4'-dihydroxyphenylalanine formation from peptidyl-tyrosine|peptidyl-L-3',4'-dihydroxyphenylalanine anabolism from peptidyl-tyrosine|peptidyl-L-3',4'-dihydroxyphenylalanine synthesis from peptidyl-tyrosine				RESID:AA0146									biological_process											owl:Class	
GO:0051118	biolink:NamedThing	glucan endo-1,3-alpha-glucosidase activity	Catalysis of the endohydrolysis of (1->3)-alpha-D-glucosidic linkages in isolichenin, pseudonigeran and nigeran.	tmpzr1t_l9r_go_relaxed.owl	endo-(1->3)-alpha-glucanase activity|endo-1,3-alpha-glucanase activity|cariogenase activity|1,3(1,3;1,4)-alpha-D-glucan 3-glucanohydrolase activity|endo-1,3-alpha-D-glucanase activity|cariogenanase activity|mutanase activity				MetaCyc:3.2.1.59-RXN|EC:3.2.1.59									molecular_function											owl:Class	
GO:0031875	biolink:NamedThing	type 4 proteinase activated receptor binding	Binding to a type 4 proteinase activated receptor.	tmpzr1t_l9r_go_relaxed.owl	type 4 proteinase activated receptor ligand													molecular_function											owl:Class	
GO:0047822	biolink:NamedThing	hypotaurine dehydrogenase activity	Catalysis of the reaction: H(2)O + hypotaurine + NAD(+) = H(+) + NADH + taurine.	tmpzr1t_l9r_go_relaxed.owl	hypotaurine:NAD+ oxidoreductase activity				MetaCyc:HYPOTAURINE-DEHYDROGENASE-RXN|RHEA:17385|Reactome:R-HSA-1655453|EC:1.8.1.3|KEGG_REACTION:R01681									molecular_function											owl:Class	
GO:0033064	biolink:NamedThing	XRCC2-RAD51D complex	A heterodimeric DNA recombinase mediator complex that contains the Rad51 paralogs RAD51D and XRCC2, or orthologs thereof; conserved from fission yeast to human but absent from budding yeast.	tmpzr1t_l9r_go_relaxed.owl	DX2 complex													cellular_component											owl:Class	
GO:0090117	biolink:NamedThing	endosome to lysosome transport of low-density lipoprotein particle	The directed movement of low-density lipoprotein particle from endosomes to lysosomes.	tmpzr1t_l9r_go_relaxed.owl	endosome to lysosome transport of LDL							tb	2009-12-07T12:04:34Z					biological_process											owl:Class	
GO:0046806	biolink:NamedThing	viral scaffold	A complex of proteins that form a scaffold around which the viral capsid is constructed.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0021629	biolink:NamedThing	olfactory nerve structural organization	The process that contributes to the act of creating the structural organization of the oculomotor nerve. This process pertains to the physical shaping of a rudimentary structure. The olfactory nerve is a collection of sensory nerve rootlets that extend down from the olfactory bulb to the olfactory mucosa of the upper parts of the nasal cavity. This nerve conducts odor information to the brainstem.	tmpzr1t_l9r_go_relaxed.owl	olfactory nerve structural organisation|CN I structural organization													biological_process											owl:Class	
GO:0006539	biolink:NamedThing	glutamate catabolic process via 2-oxoglutarate	The chemical reactions and pathways resulting in the breakdown of glutamate, via the intermediate 2-oxoglutarate.	tmpzr1t_l9r_go_relaxed.owl	glutamate catabolic process via 2-ketoglutarate|glutamate degradation via 2-oxoglutarate|glutamate catabolism via alpha-oxoglutarate|glutamate breakdown via 2-oxoglutarate|glutamate catabolism via 2-ketoglutarate|glutamate catabolism via alpha-ketoglutarate|glutamate catabolic process via alpha-ketoglutarate|glutamate catabolic process via alpha-oxoglutarate				MetaCyc:P162-PWY									biological_process											owl:Class	
GO:0015957	biolink:NamedThing	bis(5'-nucleosidyl) oligophosphate biosynthetic process	The chemical reactions and pathways resulting in the formation of a bis(5'-nucleosidyl) oligophosphate, a compound formed of two nucleosides joined together through their 5' carbons by a chain of phosphate molecules.	tmpzr1t_l9r_go_relaxed.owl	bis(5'-nucleosidyl) oligophosphate synthesis|bis(5'-nucleosidyl) oligophosphate biosynthesis|bis(5'-nucleosidyl) oligophosphate anabolism|bis(5'-nucleosidyl) oligophosphate formation													biological_process											owl:Class	
GO:0004061	biolink:NamedThing	arylformamidase activity	Catalysis of the reaction: N-formyl-L-kynurenine + H2O = formate + L-kynurenine.	tmpzr1t_l9r_go_relaxed.owl	formylkynurenine formamidase activity|formylase activity|kynurenine formamidase activity|formamidase I|formylkynureninase activity|aryl-formylamine amidohydrolase activity|formamidase II				MetaCyc:ARYLFORMAMIDASE-RXN|RHEA:13009|EC:3.5.1.9|Reactome:R-HSA-71189									molecular_function											owl:Class	
GO:0018978	biolink:NamedThing	anaerobic 1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane metabolic process	The chemical reactions and pathways involving 1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane (DDT), a chlorinated, broad spectrum, contact insecticide, in the absence of oxygen.	tmpzr1t_l9r_go_relaxed.owl	anaerobic DDT metabolic process|anaerobic DDT metabolism|anaerobic 1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane metabolism				UM-BBD_pathwayID:ddt2									biological_process											owl:Class	
GO:1990593	biolink:NamedThing	nascent polypeptide-associated complex binding	Binding to nascent polypeptide-associated complex, a heterodimeric protein complex that can reversibly bind to ribosomes and is located in direct proximity to newly synthesized polypeptide chains as they emerge from the ribosome.	tmpzr1t_l9r_go_relaxed.owl	NAC binding|NACA binding							mcc	2014-12-15T22:20:45Z					molecular_function											owl:Class	
GO:0047015	biolink:NamedThing	3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity	Catalysis of the reaction: NAD+ + 2-methyl-3-hydroxybutyryl-CoA = NADH + H+ + 2-methylaceto-acetyl-CoA.	tmpzr1t_l9r_go_relaxed.owl	2-methyl-3-hydroxy-butyryl CoA dehydrogenase activity|2-methyl-3-hydroxybutyryl coenzyme A dehydrogenase activity|2-methyl-3-hydroxybutyryl-CoA dehydrogenase activity|(2S,3S)-3-hydroxy-2-methylbutanoyl-CoA:NAD+ oxidoreductase activity				RHEA:13281|EC:1.1.1.178|MetaCyc:1.1.1.178-RXN									molecular_function											owl:Class	
GO:0070505	biolink:NamedThing	pollen coat	A layer of extracellular matrix deposited onto the surface of the pollen wall upon disintegration of the tapetal layer of the anther wall in the late stages of pollen development. The composition of this material is highly heterogeneous and includes waxes, lipid droplets, small aromatic molecules, and proteins. The pollen coat is proposed to have many functions, such as holding pollen in the anther until dispersal, facilitation of pollen dispersal, protection of pollen from water loss and UV radiation, and facilitation of adhesion of pollen to the stigma.	tmpzr1t_l9r_go_relaxed.owl	pollenkitt|tryphine													cellular_component											owl:Class	
GO:0033394	biolink:NamedThing	beta-alanine biosynthetic process via 1,3 diaminopropane	The chemical reactions and pathways resulting in the formation of beta-alanine via the intermediate 1,3 diaminopropane.	tmpzr1t_l9r_go_relaxed.owl	beta-alanine formation via 1,3 diaminopropane|beta-alanine anabolism via 1,3 diaminopropane|beta-alanine synthesis via 1,3 diaminopropane|beta-alanine biosynthesis via 1,3 diaminopropane				MetaCyc:PWY-3981									biological_process											owl:Class	
GO:0018852	biolink:NamedThing	dichloromuconate cycloisomerase activity	Catalysis of the reaction: 2,4-dichloro-2,5-dihydro-5-oxofuran-2-acetate = 2,4-dichloro-cis,cis-muconate.	tmpzr1t_l9r_go_relaxed.owl	2,4-dichloro-2,5-dihydro-5-oxofuran-2-acetate lyase (decyclizing)				EC:5.5.1.11|UM-BBD_reactionID:r0277|RHEA:17437|MetaCyc:DICHLOROMUCONATE-CYCLOISOMERASE-RXN									molecular_function											owl:Class	
GO:0102846	biolink:NamedThing	1-18:3-2-16:1-monogalactosyldiacylglycerol desaturase activity	Catalysis of the reaction: 1-18:3-2-16:1-monogalactosyldiacylglycerol + O2 + a reduced electron acceptor <=> 1-18:3-2-16:2-monogalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-8308									molecular_function											owl:Class	
GO:0031891	biolink:NamedThing	type 1 vasoactive intestinal polypeptide receptor binding	Binding to a type 1 vasoactive intestinal polypeptide receptor.	tmpzr1t_l9r_go_relaxed.owl	type 2 PACAP receptor binding|type 1 vasoactive intestinal polypeptide receptor ligand													molecular_function											owl:Class	
GO:0031890	biolink:NamedThing	vasoactive intestinal polypeptide receptor binding	Binding to a vasoactive intestinal polypeptide receptor.	tmpzr1t_l9r_go_relaxed.owl	VIP receptor binding|vasoactive intestinal polypeptide receptor ligand													molecular_function											owl:Class	
GO:0020033	biolink:NamedThing	antigenic variation	Any process involved in the biological strategy of changing antigenic determinants on the surface that are exposed to another organism's immune system.	tmpzr1t_l9r_go_relaxed.owl	surface antigen variation	https://github.com/geneontology/go-ontology/issues/18357			Wikipedia:Antigenic_variation							GO:0020034		biological_process											owl:Class	
GO:0022017	biolink:NamedThing	neuroblast division in pallium	The division of neuroblasts in the pallium. Neuroblasts are precursor cells that give rise to neurons.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0050281	biolink:NamedThing	serine-glyoxylate transaminase activity	Catalysis of the reaction: L-serine + glyoxylate = 3-hydroxypyruvate + glycine.	tmpzr1t_l9r_go_relaxed.owl	L-serine:glyoxylate aminotransferase activity|SGAT activity|serine--glyoxylate aminotransferase activity				RHEA:19125|MetaCyc:SERINE--GLYOXYLATE-AMINOTRANSFERASE-RXN|EC:2.6.1.45									molecular_function											owl:Class	
GO:0043863	biolink:NamedThing	4-hydroxy-2-ketopimelate aldolase activity	Catalysis of the reaction: 4-hydroxy-2-ketopimelate = succinate semialdehyde + pyruvate.	tmpzr1t_l9r_go_relaxed.owl	HpaI|HHED aldolase activity|HpcH|2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase activity				RHEA:25788|MetaCyc:4-HYDROXY-2-KETOPIMELATE-LYSIS-RXN									molecular_function											owl:Class	
GO:1990019	biolink:NamedThing	protein storage vacuole organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a protein storage vacuole, a storage vacuole that contains a lytic vacuole.	tmpzr1t_l9r_go_relaxed.owl								tb	2012-12-20T21:00:09Z					biological_process											owl:Class	
GO:0047521	biolink:NamedThing	3alpha,7alpha,12beta-trihydroxy-5beta-cholanate dehydrogenase activity	Catalysis of the reaction: 3alpha,7alpha,12beta-trihydroxy-5beta-cholanate + NADP(+) = 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanate + H(+) + NADPH.	tmpzr1t_l9r_go_relaxed.owl	12beta-hydroxysteroid dehydrogenase activity|12beta-hydroxysteroid:NADP+ 12-oxidoreductase activity|12beta-hydroxy steroid (nicotinamide adenine dinucleotide phosphate) dehydrogenase activity|12-beta-hydroxysteroid dehydrogenase activity				EC:1.1.1.238|MetaCyc:12-BETA-HYDROXYSTEROID-DEHYDROGENASE-RXN|RHEA:21424|KEGG_REACTION:R03495									molecular_function											owl:Class	
GO:1990453	biolink:NamedThing	nucleosome disassembly/reassembly complex	A protein complex involved in the disassembly and subsequent reassembly of nucleosomes. It associates with the coding region of transcriptionally active genes where it interacts with the RNA polymerase II and affects its processivity during co-transcriptional RNA processing and maturation. It exists as a functionally independent part of the NuA4 complex.	tmpzr1t_l9r_go_relaxed.owl	eaf5/7/3 complex					An example of this is EAF7 in Saccharomyces cerevisiae (P53911) in PMID:24843044 (inferred from direct assay).		bhm	2014-08-08T15:18:30Z					cellular_component											owl:Class	
GO:0106366	biolink:NamedThing	guanosine kinase activity	Catalysis of the reaction: ATP + guanosine = ADP + GMP.	tmpzr1t_l9r_go_relaxed.owl					RHEA:27710|EC:2.7.1.73			hjd	2021-02-23T21:18:12Z					molecular_function											owl:Class	
GO:0008977	biolink:NamedThing	prephenate dehydrogenase (NAD+) activity	Catalysis of the reaction: NAD(+) + prephenate = (4-hydroxyphenyl)pyruvate + CO(2) + NADH.	tmpzr1t_l9r_go_relaxed.owl	chorismate mutase--prephenate dehydrogenase activity|hydroxyphenylpyruvate synthase activity|prephenate:NAD+ oxidoreductase (decarboxylating)				KEGG_REACTION:R01728|EC:1.3.1.12|RHEA:13869|MetaCyc:PREPHENATEDEHYDROG-RXN									molecular_function											owl:Class	
GO:0034907	biolink:NamedThing	acetanilide 1,2-dioxygenase activity	Catalysis of the reaction: acetanilide + O2 + 2 H+ + NADH = catechol + NAD+ + acetamide.	tmpzr1t_l9r_go_relaxed.owl					EC:1.14.12.-|UM-BBD_reactionID:r0723									molecular_function											owl:Class	
GO:0042344	biolink:NamedThing	indole glucosinolate catabolic process	The chemical reactions and pathways resulting in the breakdown of indole glucosinolates, sulfur-containing compounds that have a common structure linked to an R group derived from tryptophan.	tmpzr1t_l9r_go_relaxed.owl	indole glucosinolate degradation|indole glucosinolate breakdown|indole glucosinolate catabolism													biological_process											owl:Class	
GO:0035553	biolink:NamedThing	oxidative single-stranded RNA demethylation	Removal of the methyl group from one or more nucleotides within a single-stranded RNA molecule involving the oxidation (i.e. electron loss) of one or more atoms.	tmpzr1t_l9r_go_relaxed.owl	oxidative ssRNA demethylation							bf	2010-05-14T11:05:17Z					biological_process											owl:Class	
GO:0030750	biolink:NamedThing	putrescine N-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + putrescine = N-methylputrescine + S-adenosyl-L-homocysteine + H(+).	tmpzr1t_l9r_go_relaxed.owl	S-adenosyl-L-methionine:putrescine N-methyltransferase activity|putrescine methyltransferase activity				KEGG_REACTION:R01153|RHEA:15037|EC:2.1.1.53|MetaCyc:PUTRESCINE-N-METHYLTRANSFERASE-RXN									molecular_function											owl:Class	
GO:0052694	biolink:NamedThing	jasmonoyl-isoleucine-12-hydroxylase activity	Catalysis of the reaction: jasmonoyl-isoleucine + NADPH + H+ + O2 = 12-hydroxy-jasmonoyl-isoleucine + NADP+ + H2O.	tmpzr1t_l9r_go_relaxed.owl					RHEA:54808|MetaCyc:RXN-12421									molecular_function											owl:Class	
GO:0102643	biolink:NamedThing	scalarane-17alpha-19-diol synthase activity	Catalysis of the reaction: scalarane-17alpha-19-diol <=> all-trans-geranylfarnesol + H2O.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-15755									molecular_function											owl:Class	
GO:0010242	biolink:NamedThing	oxygen evolving activity	Catalysis of the reaction: 2 H2O = O2 + 4 H+ + 4 e-. The evolution of oxygen from oxidizing water is carried out by the oxygen evolving complex in photosystem II of plants. P680+, the photochemically oxidized reaction-center chlorophyll of PSII, is a strong biological oxidant. The reduction potential of P680+ is more positive than that of water, and thus it can oxidize water to give O2 and H+ ions. The oxygen escapes as a gas while the H+ ions remain in solution inside the thylakoid vesicle.	tmpzr1t_l9r_go_relaxed.owl	photosynthetic water oxidation				EC:1.10.3.9|MetaCyc:RXN0-5265|MetaCyc:PSII-RXN|RHEA:36359									molecular_function											owl:Class	
GO:1990414	biolink:NamedThing	replication-born double-strand break repair via sister chromatid exchange	The repair of a replication-born double-strand DNA break in which the DNA molecule is repaired using the homologous sequence of the sister chromatid which serves as a template to repair the breaks.	tmpzr1t_l9r_go_relaxed.owl	replication-born DSB repair by SCE							rb	2014-07-10T21:20:34Z					biological_process											owl:Class	
GO:0019128	biolink:NamedThing	peptidyl-tryptophan racemization	The racemization of peptidyl-tryptophan.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0198							GO:0018374|GO:0018092		biological_process											owl:Class	
GO:1990796	biolink:NamedThing	photoreceptor cell terminal bouton	A specialized region of the axon terminus portion of a photoreceptor cell axon. A photoreceptor cell is a neuron specialized to detect and transduce light.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-07-09T21:33:40Z					cellular_component											owl:Class	
GO:0033456	biolink:NamedThing	GCG codon-amino acid adaptor activity	A triplet codon-amino acid adaptor activity that recognizes a GCG codon.	tmpzr1t_l9r_go_relaxed.owl	alanine tRNA					Note that in the standard genetic code, GCG codes for alanine.								molecular_function											owl:Class	
GO:0047422	biolink:NamedThing	N-acyl-D-aspartate deacylase activity	Catalysis of the reaction: N-acyl-D-aspartate + H(2)O = D-aspartate + a carboxylate.	tmpzr1t_l9r_go_relaxed.owl	N-acyl-D-aspartate amidohydrolase activity				MetaCyc:3.5.1.83-RXN|RHEA:18285|KEGG_REACTION:R02182|EC:3.5.1.83									molecular_function											owl:Class	
GO:0043571	biolink:NamedThing	maintenance of CRISPR repeat elements	Any process involved in sustaining CRISPR repeat clusters, including capture of new spacer elements, expansion or contraction of clusters, propagation of the leader sequence and repeat clusters within a genome, transfer of repeat clusters and CRISPR-associated (cas) genes to new genomes, transcription of the CRISPR repeat arrays into RNA and processing, and interaction of CRISPR/cas loci with the host genome. CRISPR (clustered regularly interspaced short palindromic repeat) elements are a family of sequence elements containing multiple direct repeats of 24-48 bp with weak dyad symmetry which are separated by regularly sized nonrepetitive spacer sequences.	tmpzr1t_l9r_go_relaxed.owl	CRISPR element metabolism|maintenance of clustered regularly interspaced short palindromic repeat elements|CRISPR element metabolic process													biological_process											owl:Class	
GO:0034714	biolink:NamedThing	type III transforming growth factor beta receptor binding	Binding to a type III transforming growth factor beta receptor.	tmpzr1t_l9r_go_relaxed.owl	TGF-beta type III binding|betaglycan binding|transforming growth factor beta receptor type III binding|transforming growth factor beta ligand binding to type III receptor|type IIII TGF-beta binding													molecular_function											owl:Class	
GO:0047836	biolink:NamedThing	D-tryptophan N-malonyltransferase activity	Catalysis of the reaction: D-tryptophan + malonyl-CoA = N(2)-malonyl-D-tryptophan + CoA + H(+).	tmpzr1t_l9r_go_relaxed.owl	malonyl-CoA:D-tryptophan N-malonyltransferase activity				MetaCyc:D-TRYPTOPHAN-N-MALONYLTRANSFERASE-RXN|KEGG_REACTION:R02482|EC:2.3.1.112|RHEA:23320									molecular_function											owl:Class	
GO:0047823	biolink:NamedThing	D-glutamyltransferase activity	Catalysis of the reaction: L(or D)-glutamine + D-glutamyl-peptide = NH3 + 5-glutamyl-D-glutamyl-peptide.	tmpzr1t_l9r_go_relaxed.owl	D-glutamyl transpeptidase activity|D-gamma-glutamyl transpeptidase activity|glutamine:D-glutamyl-peptide 5-glutamyltransferase activity				EC:2.3.2.1|MetaCyc:D-GLUTAMYLTRANSFERASE-RXN|RHEA:35623									molecular_function											owl:Class	
GO:0110008	biolink:NamedThing	ncRNA deadenylation	Shortening of the poly(A) tail of a nuclear-transcribed ncRNA.	tmpzr1t_l9r_go_relaxed.owl								kmv						biological_process											owl:Class	
GO:1904886	biolink:NamedThing	beta-catenin destruction complex disassembly	The disaggregation of a beta-catenin destruction complex into its constituent components.	tmpzr1t_l9r_go_relaxed.owl	dissociation of beta-catenin degradation complex|BDC disassembly|Axin-APC-beta-catenin-GSK3B complex disassembly|APC-Axin-1-beta-catenin complex disassembly|beta-catenin degradation complex disassembly|23S APC complex disassembly							bf	2016-01-05T11:41:02Z					biological_process											owl:Class	
GO:0047132	biolink:NamedThing	dihydrobenzophenanthridine oxidase activity	Catalysis of the reaction: O2 + dihydrosanguinarine = H2O2 + sanguinarine.	tmpzr1t_l9r_go_relaxed.owl	dihydrobenzophenanthridine:oxygen oxidoreductase activity				RHEA:16621|EC:1.5.3.12|MetaCyc:1.5.3.12-RXN									molecular_function											owl:Class	
GO:0004089	biolink:NamedThing	carbonate dehydratase activity	Catalysis of the reaction: H2CO3 = CO2 + H2O.	tmpzr1t_l9r_go_relaxed.owl	carbonic anhydrase A|carbonic dehydratase activity|anhydrase activity|carbonate anhydrase activity|carbonate hydro-lyase (carbon-dioxide-forming)|carbonic acid anhydrase activity|carbonic anhydrase activity|carbonate hydro-lyase activity|carboxyanhydrase activity				MetaCyc:CARBODEHYDRAT-RXN|Reactome:R-HSA-1475435|Reactome:R-HSA-1475022|Reactome:R-HSA-1237059|EC:4.2.1.1|RHEA:10748|Reactome:R-HSA-1475025|Reactome:R-HSA-1237081|Reactome:R-HSA-1475017|Reactome:R-HSA-1237047|Reactome:R-HSA-1475028|Reactome:R-HSA-1475436|Reactome:R-HSA-1475032|Reactome:R-HSA-1475026|Reactome:R-HSA-1237045									molecular_function											owl:Class	
GO:0102997	biolink:NamedThing	progesterone 5beta- reductase activity	Catalysis of the reaction: H+ + progesterone + NADPH <=> 5beta-pregnane-3,20-dione + NADP.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-9726									molecular_function											owl:Class	
GO:0061336	biolink:NamedThing	cell morphogenesis involved in Malpighian tubule morphogenesis	The shape change of an epithelial cell from a columnar to squamous cell morphology that contributes to the shaping of the Malpighian tubule.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-09-28T02:11:47Z					biological_process											owl:Class	
GO:1990007	biolink:NamedThing	membrane stack	A configuration of endoplasmic reticulum (ER) found in Purkinje cells in the cerebellum and in axons in the lateral vestibular nucleus, consisting of parallel and interconnecting tubules whose outer surfaces are covered by particles or ringlike structures.	tmpzr1t_l9r_go_relaxed.owl					NIF_Subcellular:sao2114874506			pr	2012-12-11T14:58:16Z					cellular_component											owl:Class	
GO:0050184	biolink:NamedThing	phosphatidylcholine desaturase activity	Catalysis of the reaction: 1-acyl-2-oleoyl-sn-glycero-3-phosphocholine + NAD(+) = 1-acyl-2-linoleoyl-sn-glycero-3-phosphocholine + H(+) + NADH.	tmpzr1t_l9r_go_relaxed.owl	linoleate synthase activity|oleoylphosphatidylcholine desaturase activity|oleate desaturase activity|1-acyl-2-oleoyl-sn-glycero-3-phosphocholine:NAD+ delta12-oxidoreductase activity|acyl-lipid omega-6 desaturase (cytochrome b5)|oleoyl-CoA desaturase activity				MetaCyc:PHOSPHATIDYLCHOLINE-DESATURASE-RXN|RHEA:12564|EC:1.14.19.22|KEGG_REACTION:R03475									molecular_function											owl:Class	
GO:0102612	biolink:NamedThing	syn-pimaradiene 6beta-hydroxylase activity	Catalysis of the reaction: 9beta-pimara-7,15-diene + NADPH + O2 + H+ <=> 6beta-hydroxy-syn-pimaradiene + NADP + H2O.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-15452									molecular_function											owl:Class	
GO:0036164	biolink:NamedThing	cell-abiotic substrate adhesion	The attachment of a cell to an underlying abiotic (non-living) substrate via adhesion molecules.	tmpzr1t_l9r_go_relaxed.owl	cell-abiotic surface adhesion							bf	2012-03-27T11:18:33Z					biological_process											owl:Class	
GO:0052690	biolink:NamedThing	trichloro-p-hydroquinone reductive dehalogenase activity	Catalysis of the reaction: 2,3,6-trichlorohydroquinone + 2 glutathione = 2,6-dichlorohydroquinone + glutathione disulfide + HCl.	tmpzr1t_l9r_go_relaxed.owl	trichlorohydroquinone reductive dehalogenase activity|xenobiotic reductase activity|pentaerythritol tetranitrate reductase activity|tetrachlorohydroquinone reductive dehalogenase activity				UM-BBD_reactionID:r0315|RHEA:56832									molecular_function											owl:Class	
GO:0050379	biolink:NamedThing	UDP-glucuronate 5'-epimerase activity	Catalysis of the reaction: UDP-alpha-D-glucuronate = UDP-L-iduronate.	tmpzr1t_l9r_go_relaxed.owl	UDP-glucuronic acid epimerase activity|UDP-glucuronic acid 5'-epimerase activity|UDPglucuronate 5'-epimerase activity|UDP-glucuronate 5' epimerase activity|uridine diphosphoglucuronate 5'-epimerase activity|C-5-uronosyl epimerase activity				Reactome:R-HSA-2024100|Reactome:R-HSA-2076371|KEGG_REACTION:R01387|MetaCyc:UDP-GLUCURONATE-5-EPIMERASE-RXN									molecular_function											owl:Class	
GO:0097135	biolink:NamedThing	cyclin E2-CDK2 complex	A protein complex consisting of cyclin E2 and cyclin-dependent kinase 2 (CDK2). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner.	tmpzr1t_l9r_go_relaxed.owl								pr	2011-08-01T01:59:57Z					cellular_component											owl:Class	
GO:0102950	biolink:NamedThing	indole-3-acetyl-valine synthetase activity	Catalysis of the reaction: indole-3-acetate + L-valine  + ATP = H+ + indole-3-acetyl-valine + AMP + diphosphoric acid.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-9083									molecular_function											owl:Class	
GO:0044563	biolink:NamedThing	envenomation resulting in slowing of activation kinetics of voltage-gated potassium channel in other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with a resultant slowing of the activation kinetics of the activity of a voltage-gated potassium channel in the bitten/stung organism.	tmpzr1t_l9r_go_relaxed.owl	voltage-dependence of activation shift (to the left)							jl	2012-04-05T04:06:29Z					biological_process											owl:Class	
GO:0030114	biolink:NamedThing	slime layer	A slime layer is an easily removed, diffuse, unorganized layer of extracellular material that surrounds a cell. Specifically this consists mostly of exopolysaccharides, glycoproteins, and glycolipids.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Slime_layer									cellular_component											owl:Class	
GO:0043730	biolink:NamedThing	5-ureido-4-imidazole carboxylate hydrolase activity	Catalysis of the reaction: 5-ureido-4-imidazole carboxylate + H2O = 5-amino-4-imidazole carboxylate + NH3 + CO2.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0050504	biolink:NamedThing	mannosyl-3-phosphoglycerate synthase activity	Catalysis of the reaction: 3-phospho-D-glycerate + GDP-alpha-D-mannose = 2-(alpha-D-mannosyl)-3-phosphoglycerate + GDP + H(+).	tmpzr1t_l9r_go_relaxed.owl	MPG synthase activity|GDP-mannose:3-phosphoglycerate 3-alpha-D-mannosyltransferase activity				RHEA:13537|MetaCyc:2.4.1.217-RXN|EC:2.4.1.217|KEGG_REACTION:R05768									molecular_function											owl:Class	
GO:0006880	biolink:NamedThing	intracellular sequestering of iron ion	The process of binding or confining iron ions in an intracellular area such that they are separated from other components of a biological system.	tmpzr1t_l9r_go_relaxed.owl	intracellular sequestration of iron ion|intracellular retention of iron ion|intracellular iron ion sequestering|intracellular iron ion retention|intracellular iron ion sequestration|intracellular iron ion storage|intracellular storage of iron ion													biological_process											owl:Class	
GO:0072585	biolink:NamedThing	xanthosine nucleotidase activity	Catalysis of the reaction: xanthosine + H2O = D-ribose + xanthine.	tmpzr1t_l9r_go_relaxed.owl	xanthosine ribohydrolase activity				MetaCyc:RXN0-363|RHEA:27994			mah	2011-02-08T04:38:31Z					molecular_function											owl:Class	
GO:0009576	biolink:NamedThing	leucoplast stroma	The space enclosed by the double membrane of a leucoplast.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0046473	biolink:NamedThing	phosphatidic acid metabolic process	The chemical reactions and pathways involving phosphatidic acid, any derivative of glycerol phosphate in which both the remaining hydroxyl groups of the glycerol moiety are esterified with fatty acids.	tmpzr1t_l9r_go_relaxed.owl	phosphatidic acid metabolism													biological_process											owl:Class	
GO:0102562	biolink:NamedThing	hydroxyproline O-arbinofuranose transferase activity	Catalysis of the reaction: UDP-beta-L-arabinofuranose + a [protein]-trans-4-hydroxy-L-proline = UDP + H+ + a protein-O-(beta-L-arabinofuranose)-trans-4-hydroxy-L-proline.	tmpzr1t_l9r_go_relaxed.owl					RHEA:49472|MetaCyc:RXN-15011									molecular_function											owl:Class	
GO:0035628	biolink:NamedThing	cystic duct development	The progression of the cystic duct over time, from its formation to the mature structure. The cystic duct runs from the gall bladder to the common bile duct.	tmpzr1t_l9r_go_relaxed.owl								bf	2010-12-10T01:24:28Z					biological_process											owl:Class	
GO:0102995	biolink:NamedThing	angelicin synthase activity	Catalysis of the reaction: columbianetin + NADPH + O2 + H+ <=> angelicin + acetone + NADP + 2 H2O.	tmpzr1t_l9r_go_relaxed.owl					EC:1.14.14.148|RHEA:27481|MetaCyc:RXN-9689									molecular_function											owl:Class	
GO:0044849	biolink:NamedThing	estrous cycle	A type of ovulation cycle, which occurs in most mammalian therian females, where the endometrium is resorbed if pregnancy does not occur.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Estrous_cycle			jl	2014-07-16T13:41:42Z					biological_process											owl:Class	
GO:0050089	biolink:NamedThing	mannose isomerase activity	Catalysis of the reaction: D-mannose = D-fructose.	tmpzr1t_l9r_go_relaxed.owl	D-mannose isomerase activity|D-mannose aldose-ketose-isomerase activity|D-mannose ketol-isomerase activity				EC:5.3.1.7|KEGG_REACTION:R00877|RHEA:22604|MetaCyc:MANNOSE-ISOMERASE-RXN									molecular_function											owl:Class	
GO:0070594	biolink:NamedThing	juvenile hormone response element binding	Binding to a juvenile hormone response element (JHRE), a conserved sequence found in the promoters of genes whose expression is regulated in response to juvenile hormone.	tmpzr1t_l9r_go_relaxed.owl	JHRE binding					Note that as agreed during the transcription overhaul, terms specifying binding to specific transcription regulatory motifs are no longer being created. The level of specificity GO has decided to go to is the "core promoter", "core promoter proximal region" and "enhancer". To capture more detail, please consider using column 16.		mah	2009-04-28T03:31:27Z					molecular_function											owl:Class	
GO:0005715	biolink:NamedThing	late recombination nodule	An electron dense structure that is associated with meiotic chromosomes in pachytene during meiosis I.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0018855	biolink:NamedThing	2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA synthetase activity	Catalysis of the reaction: 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetate + ATP + CoA = AMP + diphosphate + 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0429|RHEA:33419|EC:6.2.1.38									molecular_function											owl:Class	
GO:0031844	biolink:NamedThing	type 4 neuropeptide Y receptor binding	Binding to a type 4 neuropeptide Y receptor.	tmpzr1t_l9r_go_relaxed.owl	pancreatic polypeptide receptor binding|type 4 neuropeptide Y receptor ligand													molecular_function											owl:Class	
GO:0102002	biolink:NamedThing	valine N-monooxygenase (oxime forming) activity	Catalysis of the reaction: L-valine + 2 O2 + 2 NADPH(4-) + 2 H+ <=> (E)-2-methylpropanal oxime + 2 NADP(3-) + carbon dioxide + 3 H2O.	tmpzr1t_l9r_go_relaxed.owl					EC:1.14.14.38|RHEA:28606|MetaCyc:1.14.13.118-RXN									molecular_function											owl:Class	
GO:0047602	biolink:NamedThing	acetoacetate decarboxylase activity	Catalysis of the reaction: acetoacetate + H(+) = acetone + CO(2).	tmpzr1t_l9r_go_relaxed.owl	acetoacetate carboxy-lyase activity|acetoacetate carboxy-lyase (acetone-forming)|acetoacetic acid decarboxylase activity				KEGG_REACTION:R01366|EC:4.1.1.4|RHEA:19729|MetaCyc:ACETOACETATE-DECARBOXYLASE-RXN									molecular_function											owl:Class	
GO:0034713	biolink:NamedThing	type I transforming growth factor beta receptor binding	Binding to a type I transforming growth factor beta receptor.	tmpzr1t_l9r_go_relaxed.owl	baboon ligand|sax binding|thickveins binding|tkv binding|type I TGF-beta binding|tkv ligand|babo ligand|transforming growth factor beta ligand binding to type I receptor|saxophone binding|sax ligand|thickveins ligand|baboon receptor ligand|baboon binding|saxophone ligand|babo binding|TGF-beta type I binding|transforming growth factor beta receptor type I binding											GO:0005116|GO:0005103|GO:0005120		molecular_function											owl:Class	
GO:0097726	biolink:NamedThing	LEM domain binding	Binding to a LEM domain. The LEM domain (for lamina-associated polypeptide, emerin, MAN1 domain) is present in a group of nuclear proteins that bind chromatin through interaction of the LEM motif with the conserved DNA crosslinking protein, barrier-to-autointegration factor (BAF).	tmpzr1t_l9r_go_relaxed.owl	lamina-associated polypeptide, emerin, MAN1 domain binding|LAP2, emerin, MAN1 domain binding							pr	2016-09-19T10:19:02Z					molecular_function											owl:Class	
GO:0004951	biolink:NamedThing	cholecystokinin receptor activity	Combining with cholecystokinin and transmitting the signal across the membrane by activating an associated G-protein to initiate a change in cell activity. Cholecystokinin can act as a neuropeptide or as a gastrointestinal hormone.	tmpzr1t_l9r_go_relaxed.owl	CCK receptor activity													molecular_function											owl:Class	
GO:0046820	biolink:NamedThing	4-amino-4-deoxychorismate synthase activity	Catalysis of the reaction: L-glutamine + chorismate = 4-amino-4-deoxychorismate + L-glutamate. It is composed of two enzymatic activities (which may be present on one or two polypeptides); the first is a glutaminase which yields ammonia from glutamine, releasing glutamate. The ammonia is used by the second activity which catalyzes the amination of chorismate to form 4-amino-4-deoxychorismate.	tmpzr1t_l9r_go_relaxed.owl	para-aminobenzoic acid (PABA) synthase|ADC synthase activity|p-aminobenzoate synthetase|PabB activity|chorismate:L-glutamine amido-ligase activity|aminodeoxychorismate synthase activity|para-aminobenzoic acid synthase activity				EC:2.6.1.85|KEGG_REACTION:R01716|RHEA:11672|MetaCyc:PABASYN-RXN	Note that the name 'para-aminobenzoic acid synthase' was initially given to the 'aminodeoxychorismate synthase' activity before the additional 4-amino-4-deoxychorismate lyase activity was discovered. It is the lyase activity that actually produces para-aminobenzoic acid from 4-amino-4-deoxychorismate.								molecular_function											owl:Class	
GO:0102508	biolink:NamedThing	cyanidin 3,7-diglucoside glucosidase activity	Catalysis of the reaction: cyanidin 3,7-di-O-beta-D-glucoside betaine + H2O <=> cyanidin 3-O-beta-D-glucoside betaine + beta-D-glucose.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-14435									molecular_function											owl:Class	
GO:0015212	biolink:NamedThing	cytidine transmembrane transporter activity	Enables the transfer of cytidine, cytosine riboside, from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0106226	biolink:NamedThing	peptide 2-hydroxyisobutyryltransferase activity	Catalysis of the reaction: 2-hydroxyisobutyryl-CoA + lysine in peptide = CoA + N-2-hydroxyisobutyryl-lysine-peptide.	tmpzr1t_l9r_go_relaxed.owl					RHEA:24180			hjd	2019-10-17T18:55:24Z					molecular_function											owl:Class	
GO:0034779	biolink:NamedThing	4-isopropenyl-2-ketocyclohexane-1-carboxyl-CoA hydrolase activity	Catalysis of the reaction: 4-isopropenyl-2-ketocyclohexane-1-carboxyl-CoA + H2O = 3-isopropenylpimelyl-CoA.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r1004									molecular_function											owl:Class	
GO:0030591	biolink:NamedThing	2'-deoxyguanosine DNA ADP-ribosyltransferase activity	Catalysis of the transfer of the ADP-ribose group of NAD+ to the amino group at N2 of 2'-deoxyguanosine to yield N2-(alpha-ADP-ribos-1-yl)-2'-deoxyguanosine and its beta form.	tmpzr1t_l9r_go_relaxed.owl	NAD DNA ADP-ribosyltransferase activity													molecular_function											owl:Class	
GO:0021748	biolink:NamedThing	dorsal cochlear nucleus development	The process whose specific outcome is the progression of the dorsal cochlear nucleus over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0050406	biolink:NamedThing	[acetyl-CoA carboxylase]-phosphatase activity	Catalysis of the reaction: [acetyl-CoA carboxylase]-phosphate + H2O = [acetyl-CoA carboxylase] + phosphate.	tmpzr1t_l9r_go_relaxed.owl	acetyl-CoA:carbon-dioxide ligase (ADP-forming)-phosphate phosphohydrolase activity|acetyl-CoA carboxylase-phosphatase activity				MetaCyc:ACETYL-COA-CARBOXYLASE-PHOSPHATASE-RXN|RHEA:17125|EC:3.1.3.44									molecular_function											owl:Class	
GO:0050009	biolink:NamedThing	isopropanol dehydrogenase (NADP+) activity	Catalysis of the reaction: NADP(+) + propan-2-ol = acetone + H(+) + NADPH.	tmpzr1t_l9r_go_relaxed.owl	propan-2-ol:NADP+ oxidoreductase activity				EC:1.1.1.80|MetaCyc:ISOPROPANOL-DEHYDROGENASE-NADP+-RXN|KEGG_REACTION:R01550|RHEA:21792									molecular_function											owl:Class	
GO:0010494	biolink:NamedThing	cytoplasmic stress granule	A dense aggregation in the cytosol composed of proteins and RNAs that appear when the cell is under stress.	tmpzr1t_l9r_go_relaxed.owl	stress granule|cytoplasmic mRNP granule				Wikipedia:Stress_granule									cellular_component											owl:Class	
GO:0033799	biolink:NamedThing	myricetin 3'-O-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + myricetin = S-adenosyl-L-homocysteine + laricitrin.	tmpzr1t_l9r_go_relaxed.owl	CrCOMT2|flavonoid 3',5'-O-dimethyltransferase activity|myricetin 3-O-methyltransferase activity|S-adenosyl-L-methionine:myricetin O-methyltransferase activity				MetaCyc:RXN-13912|KEGG_REACTION:R06815|RHEA:25629|EC:2.1.1.267;|MetaCyc:RXN-8451	Note that this term represents one of two reactions that are grouped together in EC:2.1.1.267						GO:0102437		molecular_function											owl:Class	
GO:0047309	biolink:NamedThing	dihydroxyphenylalanine transaminase activity	Catalysis of the reaction: 2-oxoglutarate + L-dopa = 3,4-dihydroxyphenylpyruvate + L-glutamate.	tmpzr1t_l9r_go_relaxed.owl	DOPA aminotransferase activity|glutamate-DOPP transaminase (GDT)|dopa transaminase activity|dihydroxyphenylalanine aminotransferase activity|3,4-dihydroxy-L-phenylalanine:2-oxoglutarate aminotransferase activity|L-dopa transaminase activity|aspartate-DOPP transaminase (ADT)|phenylalanine-DOPP transaminase (PDT)				MetaCyc:2.6.1.49-RXN|RHEA:15273|EC:2.6.1.49|KEGG_REACTION:R02077									molecular_function											owl:Class	
GO:0110069	biolink:NamedThing	syncytial embryo cellularization	The separation of a syncytial embryo into individual cells.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/14543						kmv	2017-11-22T19:59:19Z					biological_process											owl:Class	
GO:0000252	biolink:NamedThing	C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity	Catalysis of the reaction: 3-beta-hydroxy-4-beta-methyl-5-alpha-cholesta-8,24-dien-4-alpha-carboxylate + NAD(P)+ = 4-alpha-methyl-5-alpha-cholesta-8,24-dien-3-one + CO2 + NAD(P)H.	tmpzr1t_l9r_go_relaxed.owl	C-3 sterol dehydrogenase activity|3beta-hydroxy-4beta-methylcholestenecarboxylate 3-dehydrogenase (decarboxylating)|3beta-hydroxy-4beta-methylcholestenoate dehydrogenase activity|sterol-4alpha-carboxylate 3-dehydrogenase (decarboxylating)|3beta-hydroxy-4alpha-methylcholestenecarboxylate 3-dehydrogenase (decarboxylating)|sterol-4-carboxylate 3-dehydrogenase (decarboxylating) activity|C-3 sterol dehydrogenase (C-4 decarboxylase) activity|3beta-hydroxy-4beta-methyl-5alpha-cholest-7-ene-4alpha-carboxylate:NAD(P)+ 3-oxidoreductase (decarboxylating)|sterol 4alpha-carboxylic decarboxylase activity				Reactome:R-HSA-194718|Reactome:R-HSA-194642|EC:1.1.1.170	Note that zymosterol is cholesta-8,24-dien-3-ol.								molecular_function											owl:Class	
GO:0102233	biolink:NamedThing	crotonaldehyde redutase activity	Catalysis of the reaction: (cis)-crotonaldehyde + NADPH + H+ <=> butanal + NADP.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-12292									molecular_function											owl:Class	
GO:0090551	biolink:NamedThing	response to manganese starvation	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of manganese.	tmpzr1t_l9r_go_relaxed.owl								tb	2013-04-22T13:57:16Z					biological_process											owl:Class	
GO:0048098	biolink:NamedThing	antennal joint development	The process whose specific outcome is the progression of the antennal joint over time, from its formation to the mature structure. The antennal joint is the joint between antennal segments.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0047164	biolink:NamedThing	isoflavone-7-O-beta-glucoside 6''-O-malonyltransferase activity	Catalysis of the reaction: biochanin-A + malonyl-CoA = 6'-malonyl-biochanin A + CoA.	tmpzr1t_l9r_go_relaxed.owl	malonyl-CoA:isoflavone-7-O-beta-D-glucoside 6''-O-malonyltransferase activity|MAT-7|flavone (flavonol) 7-O-glycoside malonyltransferase activity|malonyl-CoA:flavone/flavonol 7-O-glucoside malonyltransferase activity|malonyl-coenzyme A:flavone/flavonol-7-O-glycoside malonyltransferase activity|flavone/flavonol 7-O-beta-D-glucoside malonyltransferase activity|malonyl-coenzyme A:isoflavone 7-O-glucoside-6''-malonyltransferase activity				EC:2.3.1.115|MetaCyc:2.3.1.115-RXN|RHEA:15581									molecular_function											owl:Class	
GO:0102428	biolink:NamedThing	kaempferol-3-O-glucoside 1,6-glucosyltransferase activity	Catalysis of the reaction: kaempferol 3-O-glucoside + UDP-alpha-D-glucose <=> kaempferol-3-gentiobioside + UDP.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-13830									molecular_function											owl:Class	
GO:0070052	biolink:NamedThing	collagen V binding	Binding to a type V collagen trimer.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0030798	biolink:NamedThing	trans-aconitate 2-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + trans-aconitate = (E)-3-(methoxycarbonyl)pent-2-enedioate + S-adenosyl-L-homocysteine.	tmpzr1t_l9r_go_relaxed.owl	S-adenosyl-L-methionine:(E)-prop-1-ene-1,2,3-tricarboxylate 2'-O-methyltransferase activity				KEGG_REACTION:R05763|EC:2.1.1.144|MetaCyc:RXN0-2441|RHEA:14969									molecular_function											owl:Class	
GO:0045551	biolink:NamedThing	cinnamyl-alcohol dehydrogenase activity	Catalysis of the reaction: cinnamyl alcohol + NADP+ = cinnamaldehyde + NADPH + H+.	tmpzr1t_l9r_go_relaxed.owl	cinnamyl alcohol dehydrogenase activity|cinnamyl-alcohol:NADP+ oxidoreductase activity|CAD activity				RHEA:10392|EC:1.1.1.195|MetaCyc:CINNAMYL-ALCOHOL-DEHYDROGENASE-RXN									molecular_function											owl:Class	
GO:0050636	biolink:NamedThing	vinorine synthase activity	Catalysis of the reaction: 16-epivellosimine + acetyl-CoA = CoA + vinorine.	tmpzr1t_l9r_go_relaxed.owl	acyl-CoA:16-epivellosimine O-acetyltransferase (cyclizing)				KEGG_REACTION:R05876|MetaCyc:2.3.1.160-RXN|EC:2.3.1.160|RHEA:24016									molecular_function											owl:Class	
GO:0042807	biolink:NamedThing	central vacuole	A membrane-enclosed sac that takes up most of the volume of a mature plant cell. Functions include storage, separation of toxic byproducts, and cell growth determination.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0052693	biolink:NamedThing	epoxyqueuosine reductase activity	Catalysis of the reaction: epoxyqueuosine in tRNA + reductant = queuosine in tRNA + oxidised reductant.	tmpzr1t_l9r_go_relaxed.owl					EC:1.17.99.6|RHEA:32159									molecular_function											owl:Class	
GO:0061776	biolink:NamedThing	topological DNA co-entrapment activity	A DNA binding activity in which a protein complex interacts with more than one DNA duplex to encircle the DNA molecules with a loose fitting ring.	tmpzr1t_l9r_go_relaxed.owl	topological DNA entrapment activity	https://github.com/geneontology/go-ontology/issues/20522						dph	2016-07-13T13:10:15Z					molecular_function											owl:Class	
GO:0046904	biolink:NamedThing	calcium oxalate binding	Binding to calcium oxalate, CaC2O4, a salt of oxalic acid. In animals, it may be excreted in urine or retained in the form of urinary calculi.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0019160	biolink:NamedThing	NMN nucleosidase activity	Catalysis of the reaction: H(2)O + nicotinamide mononucleotide = D-ribose 5-phosphate + H(+) + nicotinamide.	tmpzr1t_l9r_go_relaxed.owl	nicotinamide mononucleotide nucleosidase activity|NMNGhase activity|NMN glycohydrolase activity|NMNase activity|nicotinamide-nucleotide phosphoribohydrolase activity|nicotinamide mononucleotidase activity				RHEA:23140|MetaCyc:NMNNUCLEOSID-RXN|EC:3.2.2.14|KEGG_REACTION:R01270									molecular_function											owl:Class	
GO:0099000	biolink:NamedThing	viral genome ejection through host cell envelope, contractile tail mechanism	Ejection by a non-enveloped prokaryotic virus of its genome into the host cytoplasm via a contractile tail ejection system consisting of a baseplate, a central tube and an external contractile sheath.   Upon binding to the host cell surface, the baseplate changes its conformation and triggers sheath contraction, driving the rigid internal tail tube through the cell envelope.	tmpzr1t_l9r_go_relaxed.owl	viral contractile tail ejection system				VZ:3950									biological_process											owl:Class	
GO:0052786	biolink:NamedThing	alpha-linked polysaccharide catabolism to maltotriose	The breakdown of large alpha-linked polysaccharides by hydrolysis of (1->4)-alpha-D-glucosidic linkages to yield maltotriose.	tmpzr1t_l9r_go_relaxed.owl	alpha-amylase-mediated polysaccharide catabolism, producing maltotriose|maltotriose-forming alpha-amylase activity							ai	2011-10-04T09:59:59Z					biological_process											owl:Class	
GO:0140609	biolink:NamedThing	phycocyanobilin biosynthetic process	The chemical reactions or pathway resulting in the formation of phycocyanobilin, which involves the oxidative cleavage of heme by a heme oxygenase (HO) to form biliverdin IX alpha. Biliverdin IX alpha is subsequently converted to phycocyanobilin by a ferredoxin-dependent oxidoreductase (PCYA).	tmpzr1t_l9r_go_relaxed.owl	phycocyanobilin biosynthesis	https://github.com/geneontology/go-ontology/issues/20941						pg	2021-02-24T10:02:19Z					biological_process											owl:Class	
GO:0033959	biolink:NamedThing	deoxyribodipyrimidine endonucleosidase activity	Catalysis of the cleavage of the N-glycosidic bond between the 5'-pyrimidine residue in cyclobutadipyrimidine (in DNA) and the corresponding deoxy-D-ribose residue.	tmpzr1t_l9r_go_relaxed.owl	pyrimidine dimer DNA-glycosylase activity|deoxy-D-ribocyclobutadipyrimidine polynucleotidodeoxyribohydrolase activity|deoxyribonucleate pyrimidine dimer glycosidase activity|pyrimidine dimer DNA glycosylase activity|endonuclease V activity|PD-DNA glycosylase activity|T4-induced UV endonuclease activity				EC:3.2.2.17|MetaCyc:3.2.2.17-RXN									molecular_function											owl:Class	
GO:0102159	biolink:NamedThing	baicalein 7-O-glucuronosyltransferase activity	Catalysis of the reaction: UDP-alpha-D-glucuronate + baicalein <=> H+ + UDP + baicalin.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-11755|RHEA:28314|EC:2.4.1.253									molecular_function											owl:Class	
GO:0016521	biolink:NamedThing	pituitary adenylate cyclase activating polypeptide activity	The action characteristic of pituitary adenylate cyclase activating polypeptide, a peptide produced in the hypothalamus that binds to receptors to exert pleiotropic effects including control of neurotransmitter release, vasodilation, bronchodilation, activation of intestinal motility, increase in insulin and histamine secretion, immune modulation, and stimulation of cell proliferation and differentiation.	tmpzr1t_l9r_go_relaxed.owl	pituitary adenylyl cyclase activating polypeptide activity													molecular_function											owl:Class	
GO:0002933	biolink:NamedThing	lipid hydroxylation	The covalent attachment of a hydroxyl group to one or more fatty acids in a lipid.	tmpzr1t_l9r_go_relaxed.owl	fatty acid hydroxylation							hjd	2012-04-24T02:26:33Z					biological_process											owl:Class	
GO:1990334	biolink:NamedThing	Bfa1-Bub2 complex	A protein complex that acts as a two-component GTPase-activating protein for Tem1 GTPase, thus regulating a signal transduction cascade, called the mitotic exit network (MEN), which is required for mitotic exit and cytokinesis. Bub2/Bfa1 keeps Tem1 inactive until the spindle is properly oriented, thus inhibiting MEN activation.	tmpzr1t_l9r_go_relaxed.owl								bhm	2014-03-17T14:34:21Z					cellular_component											owl:Class	
GO:0047509	biolink:NamedThing	(R)-dehydropantoate dehydrogenase activity	Catalysis of the reaction: (R)-4-dehydropantoate + H(2)O + NAD(+) = (R)-3,3-dimethylmalate + 2 H(+) + NADH.	tmpzr1t_l9r_go_relaxed.owl	D-aldopantoate dehydrogenase activity|D-2-hydroxy-3,3-dimethyl-3-formylpropionate:diphosphopyridine nucleotide (DPN+) oxidoreductase activity|(R)-4-dehydropantoate:NAD+ 4-oxidoreductase activity				EC:1.2.1.33|KEGG_REACTION:R03198|MetaCyc:R-DEHYDROPANTOATE-DEHYDROGENASE-RXN|RHEA:19349									molecular_function											owl:Class	
GO:0120274	biolink:NamedThing	virus coreceptor activity	Combining with a virus component, and in cooperation with a nearby primary receptor, initiating a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	viral coreceptor activity	https://github.com/geneontology/go-ontology/issues/20137						krc	2020-10-20T18:32:45Z					molecular_function											owl:Class	
GO:0034365	biolink:NamedThing	discoidal high-density lipoprotein particle	A newly formed high-density lipoprotein particle; consists of a phospholipid bilayer surrounded by two or more APOA1 molecules. The discoidal HDL particle is formed when lipid-free or lipid-poor APOA1 acquires phospholipids and unesterified cholesterol from either cell membranes or triglyceride-rich lipoproteins (undergoing lipolysis by lipoprotein lipase).	tmpzr1t_l9r_go_relaxed.owl	nascent high-density lipoprotein particle|discoidal HDL|nascent HDL													cellular_component											owl:Class	
GO:0034990	biolink:NamedThing	nuclear mitotic cohesin complex	A cohesin complex that mediates sister chromatid cohesion in the nucleus during mitosis; has a subunit composition distinct from that of the meiotic cohesin complex.	tmpzr1t_l9r_go_relaxed.owl						Note that this term should be used to annotate gene products found in cohesin complexes in organisms that undergo closed mitosis (i. e. where the nuclear envelope does not break down, as in fungi). For organisms in which the nuclear envelope breaks down during mitosis, the parent should be used.								cellular_component											owl:Class	
GO:0018744	biolink:NamedThing	limonene-1,2-epoxide hydrolase activity	Catalysis of the reaction: limonene-1,2-epoxide + H2O = limonene-1,2-diol. Other substrates include alicyclic and 1-methyl-substituted epoxides, such as 1-methylcyclohexene oxide, indene oxide and cyclohexene oxide.	tmpzr1t_l9r_go_relaxed.owl	limonene oxide hydrolase activity				EC:3.3.2.8|MetaCyc:3.3.2.8-RXN|UM-BBD_reactionID:r0734|RHEA:10700									molecular_function											owl:Class	
GO:0052625	biolink:NamedThing	4-aminobenzoate amino acid synthetase activity	Catalysis of the reaction: 4-aminobenzoate + ATP + amino acid = 4-aminobenzoyl amino acid conjugate + AMP + diphosphate.	tmpzr1t_l9r_go_relaxed.owl	pABA amino acid synthetase activity|p-aminobenzoate amino acid synthetase activity|p-aminobenzoyl amino acid synthetase activity|4-aminobenzoyl amino acid synthetase activity													molecular_function											owl:Class	
GO:0051595	biolink:NamedThing	response to methylglyoxal	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methylglyoxal stimulus. Methylglyoxal is a 2-oxoaldehyde derived from propanal.	tmpzr1t_l9r_go_relaxed.owl	response to pyruvaldehyde													biological_process											owl:Class	
GO:0102041	biolink:NamedThing	7,8-dihydropterin-6-yl-methyl-4-(beta-D-ribofuranosyl)aminobenzene 5'-phosphate synthase	Catalysis of the reaction: 4-(beta-D-ribofuranosyl)aminobenzene 5'-phosphate + (2-amino-4-hydroxy-7,8-dihydropteridin-6-yl)methyl diphosphate = N-[(7,8-dihydropterin-6-yl)methyl]-4-(beta-D-ribofuranosyl)aniline 5'-phosphate + diphosphoric acid.	tmpzr1t_l9r_go_relaxed.owl					EC:2.5.1.105|MetaCyc:RXN-10009|RHEA:35951									molecular_function											owl:Class	
GO:0140634	biolink:NamedThing	CARD8 inflammasome complex	An inflammasome complex that consists of CARD8 and CASP1.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/21092						pg	2021-04-09T11:24:48Z					cellular_component											owl:Class	
GO:1904275	biolink:NamedThing	tricellular tight junction disassembly	The disaggregation of a tricellular tight junction into its constituent components.	tmpzr1t_l9r_go_relaxed.owl								mr	2015-05-29T16:31:06Z					biological_process											owl:Class	
GO:0098606	biolink:NamedThing	selenocystathionine gamma-lyase activity	Catalysis of the reaction: L-Selenocystathionine + H2O => L-Selenocysteine + NH3 + 2-Oxobutanoic acid.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-2408543|RHEA:31151			dos	2014-04-16T11:20:00Z					molecular_function											owl:Class	
GO:0030354	biolink:NamedThing	melanin-concentrating hormone activity	The action characteristic of melanin-concentrating hormone, a cyclic peptide hormone that, upon receptor binding, induces melanin aggregation in melanocytes, and is also involved in regulating food intake and energy balance in mammals.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0097261	biolink:NamedThing	eoxin C4 synthase activity	Catalysis of the reaction: eoxin A4 + glutathione = eoxin C4.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-2161768			pr	2012-03-08T02:59:00Z					molecular_function											owl:Class	
GO:0047392	biolink:NamedThing	CMP-N-acylneuraminate phosphodiesterase activity	Catalysis of the reaction: H2O + CMP-N-acylneuraminate = N-acylneuraminate + CMP.	tmpzr1t_l9r_go_relaxed.owl	CMP-sialic acid hydrolase activity|CMP-sialate hydrolase activity|CMP-N-acetylneuraminate hydrolase activity|CMP-N-acylneuraminate N-acylneuraminohydrolase activity|cytidine monophosphosialic hydrolase activity|CMP-N-acylneuraminic acid hydrolase activity|cytidine monophosphate-N-acetylneuraminic acid hydrolase activity|cytidine monophosphosialate hydrolase activity				EC:3.1.4.40|RHEA:20185|MetaCyc:3.1.4.40-RXN									molecular_function											owl:Class	
GO:0102068	biolink:NamedThing	alpha-humulene 10-hydroxylase activity	Catalysis of the reaction: (1E,4E,8E)-alpha-humulene + NADPH + O2 + H+ <=> 10-hydroxy-alpha-humulene + NADP + H2O.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-10628|EC:1.14.14.113|RHEA:32491									molecular_function											owl:Class	
GO:0034003	biolink:NamedThing	vetispiradiene synthase activity	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = diphosphate + vetispiradiene.	tmpzr1t_l9r_go_relaxed.owl	vetispiradiene-forming farnesyl pyrophosphate cyclase activity|vetispiradiene cyclase activity|trans,trans-farnesyl-diphosphate diphosphate-lyase (cyclizing, vetispiradiene-forming) activity|pemnaspirodiene synthase activity|HVS				MetaCyc:RXN-4823|RHEA:10340|EC:4.2.3.21|KEGG_REACTION:R06523									molecular_function											owl:Class	
GO:0075196	biolink:NamedThing	adhesion of symbiont haustorium mother cell to host	The attachment of a haustorium mother cell of the symbiont to its host via adhesion molecules. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	adhesion of symbiont haustorium mother cell to host during symbiotic interaction					Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products from the symbiont involved in this process.								biological_process											owl:Class	
GO:0052750	biolink:NamedThing	reactive-black-5:hydrogen-peroxide oxidoreductase activity	Catalysis of the reaction: reactive black 5 + hydrogen peroxide = oxidized reactive black 5 + 2 H2O.	tmpzr1t_l9r_go_relaxed.owl	versatile peroxidase activity				EC:1.11.1.16|RHEA:22396|KEGG_REACTION:R07612|MetaCyc:RXN-8666			ai	2011-09-21T02:33:34Z					molecular_function											owl:Class	
GO:0033535	biolink:NamedThing	ajugose metabolic process	The chemical reactions and pathways involving ajugose, the hexasaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside.	tmpzr1t_l9r_go_relaxed.owl	ajugose metabolism													biological_process											owl:Class	
GO:0007639	biolink:NamedThing	homeostasis of number of meristem cells	Any biological process involved in the maintenance of the steady-state number of cells within a population of cells in the meristem.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0022035	biolink:NamedThing	rhombomere cell migration	The movement of a cell within a rhombomere. This process is known to occur as an early step in the generation of anatomical structure from a rhombomere.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0030378	biolink:NamedThing	serine racemase activity	Catalysis of the synthesis of free D-serine from L-serine.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:5.1.1.18-RXN|EC:5.1.1.18|Reactome:R-HSA-9014766|RHEA:10980									molecular_function											owl:Class	
GO:0018957	biolink:NamedThing	phenanthrene catabolic process via trans-9(S),10(S)-dihydrodiolphenanthrene	The chemical reactions and pathways resulting in the breakdown of phenanthrene, a tricyclic aromatic hydrocarbon, where trans-9(S),10(S)-dihydrodiolphenanthrene is the principal intermediate metabolite.	tmpzr1t_l9r_go_relaxed.owl	phenanthrene degradation via trans-9(S),10(S)-dihydrodiolphenanthrene|phenanthrene breakdown via trans-9(S),10(S)-dihydrodiolphenanthrene				UM-BBD_pathwayID:pha2									biological_process											owl:Class	
GO:0097265	biolink:NamedThing	5(S)-hydroxyeicosatetraenoic acid dehydrogenase activity	Catalysis of the reaction: 5-HETE + NADP(+) = 5-oxo-ETE + NADPH + H(+).	tmpzr1t_l9r_go_relaxed.owl	5-HETE dehydrogenase activity|5-hydroxy-eicosatetraenoic acid dehydrogenase activity|5(S)-HETE dehydrogenase activity				Reactome:R-HSA-2161776			pr	2012-03-09T12:46:02Z					molecular_function											owl:Class	
GO:0052611	biolink:NamedThing	beta-carotene 3-hydroxylase activity	Catalysis of the reaction: beta-carotene + a reduced electron acceptor + oxygen = beta-cryptoxanthin + an oxidized electron acceptor + H2O.	tmpzr1t_l9r_go_relaxed.owl	beta-carotene hydroxylase activity|carotene beta-ring hydroxylase activity				RHEA:30323|MetaCyc:RXN-8025									molecular_function											owl:Class	
GO:0036060	biolink:NamedThing	slit diaphragm assembly	The aggregation, arrangement and bonding together of a set of components to form a slit diaphragm, specialized cell-cell junction found between the interdigitating foot processes of the glomerular epithelium (the podocytes) in the vertebrate kidney, which is adapted for facilitating glomerular filtration.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-12-12T04:38:40Z					biological_process											owl:Class	
GO:0010435	biolink:NamedThing	3-oxo-2-(2'-pentenyl)cyclopentane-1-octanoic acid CoA ligase activity	Catalysis of the reaction: ATP + 3-oxo-2-(2'-pentenyl)-cyclopentane-1-octanoic acid + coenzyme A = AMP + diphosphate + 3-oxo-2-(2'-pentenyl)-cyclopentane-1-octanoyl-CoA + H+. 3-oxo-2-(2'-pentenyl)-cyclopentane-1-octanoic acid is also known as OPC-8:0.	tmpzr1t_l9r_go_relaxed.owl	3-oxo-2-(2'-[Z]-pentenyl)cyclopentane-1-octanoate CoA ligase activity|OPC-8:0 CoA ligase activity|3-oxo-2-(2'-pentenyl)cyclopentane-1-octanoic acid (OPC-8:0) CoA ligase activity				EC:6.2.1.-|MetaCyc:RXN-10695									molecular_function											owl:Class	
GO:0044105	biolink:NamedThing	L-xylulose reductase (NAD+) activity	Catalysis of the reaction: xylitol + NAD+ = L-xylulose + NADH + H+.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/21874						jl	2009-07-09T04:25:43Z					molecular_function											owl:Class	
GO:0019812	biolink:NamedThing	type I site-specific deoxyribonuclease complex	A multisubunit complex composed of two copies of a restriction (R) subunit, two copies of a methylation (M) subunit, and one copy of a specificity (S) subunit. This complex recognizes specific short DNA sequences (through the S subunit), and binds to them. If the recognition site is hemimethylated, the complex acts as a methyltransferase which modifies the recognition site, using S-adenosylmethionine as the methyl donor. Only the M and S subunits are required for this reaction. If the complex binds to an unmethylated recognition site, then the complex translocates the DNA bidirectionally in an ATP-dependent manner. When the translocation is stalled by impact with another complex or unusual DNA structure, the enzyme functions as an endonuclease and cleavage of the DNA will occur, hundreds or thousands of base pairs away from the recognition site. These DNA restriction systems are used by bacteria to defend against phage and other foreign DNA that may enter a cell.	tmpzr1t_l9r_go_relaxed.owl	type I restriction enzyme complex													cellular_component											owl:Class	
GO:0003194	biolink:NamedThing	sinoatrial valve formation	The developmental process pertaining to the initial formation of the sinoatrial valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable.	tmpzr1t_l9r_go_relaxed.owl	SA valve formation							dph	2009-10-08T01:12:45Z					biological_process											owl:Class	
GO:0002574	biolink:NamedThing	thrombocyte differentiation	The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of a thrombocyte, a nucleated cell found in all vertebrates but mammals involved in hemostasis.	tmpzr1t_l9r_go_relaxed.owl						Note that platelets are the non-nucleated mammalian functional equivalent of the nucleated thrombocytes of non-mammalian vertebrates and are sometimes also referred to as thrombocytes. Platelet formation in mammals is covered by the biological_process term platelet formation ; GO:0030220.								biological_process											owl:Class	
GO:0120209	biolink:NamedThing	cone telodendria	Cone telodendria are projections that originate from the cone pedicle and form gap junctions with other photoreceptors within the outer plexiform layer of the retina.	tmpzr1t_l9r_go_relaxed.owl								krc	2019-05-21T00:01:34Z					cellular_component											owl:Class	
GO:0005133	biolink:NamedThing	interferon-gamma receptor binding	Binding to an interferon-gamma receptor.	tmpzr1t_l9r_go_relaxed.owl	interferon-gamma|interferon-gamma receptor ligand													molecular_function											owl:Class	
GO:0047286	biolink:NamedThing	NAD+-diphthamide ADP-ribosyltransferase activity	Catalysis of the reaction: peptide diphthamide + NAD+ = peptide N-(ADP-D-ribosyl)diphthamide + niacinamide.	tmpzr1t_l9r_go_relaxed.owl	ADP-ribosyltransferase activity|mono(ADP-ribosyl)transferase activity|NAD+:peptide-diphthamide N-(ADP-D-ribosyl)transferase activity|NAD-diphthamide ADP-ribosyltransferase activity				RHEA:11820|EC:2.4.2.36|Reactome:R-HSA-5336421|MetaCyc:RXN-11372									molecular_function											owl:Class	
GO:0047649	biolink:NamedThing	alkylglycerol kinase activity	Catalysis of the reaction: 1-alkyl-sn-glycerol + ATP = 1-alkyl-sn-glycerol 3-phosphate + ADP + 2 H(+).	tmpzr1t_l9r_go_relaxed.owl	ATP-alkylglycerol phosphotransferase activity|ATP:1-O-alkyl-sn-glycerol 3-phosphotransferase activity|1-alkylglycerol kinase (phosphorylating)|ATP:1-alkyl-sn-glycerol phosphotransferase activity|alkylglycerol phosphotransferase activity				EC:2.7.1.93|MetaCyc:ALKYLGLYCEROL-KINASE-RXN|RHEA:16937|KEGG_REACTION:R04126									molecular_function											owl:Class	
GO:0140018	biolink:NamedThing	regulation of cytoplasmic translational fidelity	Any process that modulates the ability of the cytoplasmic translational apparatus to interpret the genetic code.	tmpzr1t_l9r_go_relaxed.owl								pg	2017-04-06T12:27:10Z					biological_process											owl:Class	
GO:1904931	biolink:NamedThing	MCM complex binding	Binding to an MCM complex.	tmpzr1t_l9r_go_relaxed.owl	mini-chromosome maintenance complex binding							mah	2016-01-29T11:48:10Z					molecular_function											owl:Class	
GO:0044556	biolink:NamedThing	envenomation resulting in negative regulation of heart rate of other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the negative regulation of the heart rate of the bitten/stung organism.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-03-29T03:04:52Z					biological_process											owl:Class	
GO:0103080	biolink:NamedThing	methylthiopropylmalate isomerase activity	Catalysis of the reaction: 2-(3-methylthiopropyl)malate(2-) <=> 3-(3'-methylthio)propylmalate.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXNQT-4164|RHEA:50644									molecular_function											owl:Class	
GO:0046693	biolink:NamedThing	sperm storage	The retention of sperm by a female following mating.	tmpzr1t_l9r_go_relaxed.owl	sperm sequestration|sperm sequestering|storage of sperm|retention of sperm|sequestration of sperm|sperm retention|sequestering of sperm													biological_process											owl:Class	
GO:0097452	biolink:NamedThing	GAIT complex	A protein complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes. The complex binds to stem loop-containing GAIT elements in the 3'-UTR of diverse inflammatory mRNAs and suppresses their translation by blocking the recruitment of the 43S ribosomal complex to m7G cap-bound eIF4G. In humans it includes RPL13A, EPRS, SYNCRIP and GAPDH; mouse complexes lack SYNCRIP.	tmpzr1t_l9r_go_relaxed.owl	IFN-gamma-activated inhibitor of translation complex|gamma interferon-activated inhibitor of translation complex							pr	2012-12-19T09:32:25Z					cellular_component											owl:Class	
GO:0046896	biolink:NamedThing	N-terminal peptidyl-leucine methylation	The methylation of the N-terminal leucine of proteins to form the derivative N-methyl-L-leucine.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0337									biological_process											owl:Class	
GO:0102431	biolink:NamedThing	acyl-lipid omega-(9-4) desaturase	Catalysis of the reaction: linoleoyl-[glycerolipid] + 2 ferrocytochrome b5 + O2 + 2 H(+) <=> pinolenoyl-[glycerolipid] + 2 ferricytochrome b5 + 2 H2O.	tmpzr1t_l9r_go_relaxed.owl	linoleate delta5 desaturase activity				MetaCyc:RXN-13858|EC:1.14.19.12|RHEA:46236									molecular_function											owl:Class	
GO:1902342	biolink:NamedThing	xylitol export	The directed movement of xylitol out of a cell or organelle.	tmpzr1t_l9r_go_relaxed.owl								se	2013-07-30T16:09:55Z					biological_process											owl:Class	
GO:0061978	biolink:NamedThing	mandibular condyle articular cartilage development	The process whose specific outcome is the progression of mandibular joint condyle articular cartilage over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl								dph	2018-02-12T20:04:49Z					biological_process											owl:Class	
GO:0061976	biolink:NamedThing	temporomandibular joint articular cartilage development	The process whose specific outcome is the progression of temporomandibular joint articular cartilage over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl								dph	2018-02-12T20:01:00Z					biological_process											owl:Class	
GO:0102257	biolink:NamedThing	1-16:0-2-18:2-phosphatidylcholine sn-1 acylhydrolase activity	Catalysis of the reaction: 1-palmitoyl-2-linoleoyl-phosphatidylcholine + H2O <=> 1-linoleoyl-sn-glycero-3-phosphocholine + hexadecanoate + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-12430									molecular_function											owl:Class	
GO:0035181	biolink:NamedThing	larval burrowing behavior	Digging into the substrate by non-feeding larvae in search for food-free sites suitable for pupation.	tmpzr1t_l9r_go_relaxed.owl	larval burrowing behaviour													biological_process											owl:Class	
GO:0009045	biolink:NamedThing	xylose isomerase activity	Catalysis of the reaction: D-xylose = D-xylulose.	tmpzr1t_l9r_go_relaxed.owl	D-xylose aldose-ketose-isomerase activity|D-xylose ketol-isomerase activity|D-xylose ketoisomerase activity|D-xylose isomerase activity				MetaCyc:XYLISOM-RXN|EC:5.3.1.5|RHEA:22816									molecular_function											owl:Class	
GO:0047787	biolink:NamedThing	delta4-3-oxosteroid 5beta-reductase activity	Catalysis of the reactions: (1) 5beta-cholestan-3-one + NADP+ = cholest-4-en-3-one + NADPH + H+ and (2) 17,21-dihydroxy-5beta-pregnane-3,11,20-trione + NADP+ = cortisone + NADPH + H+.	tmpzr1t_l9r_go_relaxed.owl	androstenedione 5beta-reductase activity|testosterone 5-beta-reductase activity|cholestenone 5beta-reductase activity|5beta-reductase activity|testosterone 5beta-reductase activity|steroid 5beta-reductase activity|delta(4)-3-ketosteroid 5-beta-reductase activity|cortisone 5-beta-reductase activity|3-oxo-Delta(4)-steroid 5-beta-reductase activity|cortisone delta(4)-5-beta-reductase activity|delta(4)-5-beta-reductase activity|delta4-3-ketosteroid 5beta-reductase activity|cholestenone 5-beta-reductase activity|delta4-hydrogenase activity|delta(4)-hydrogenase activity|5beta-cholestan-3-one:NADP+ 4,5-oxidoreductase activity|3-oxo-5beta-steroid:NADP+ delta4-oxidoreductase activity|delta4-3-oxosteroid 5-beta-reductase activity|steroid 5-beta-reductase activity|3-oxo-delta4-steroid 5beta-reductase activity|cortisone b-reductase activity|4,5beta-dihydrocortisone:NADP+ delta4-oxidoreductase activity|5-beta-reductase activity|delta4-5beta-reductase activity|cholestenone 5b-reductase activity|cortisone delta4-5beta-reductase activity|cortisone 5beta-reductase activity|cortisone beta-reductase activity|androstenedione 5-beta-reductase activity				MetaCyc:CHOLESTENONE-5-BETA-REDUCTASE-RXN|EC:1.3.1.3|MetaCyc:CORTISONE-BETA-REDUCTASE-RXN							GO:0047752		molecular_function											owl:Class	
GO:0050015	biolink:NamedThing	kievitone hydratase activity	Catalysis of the reaction: kievitone hydrate = H(2)O + H(+) + kievitone.	tmpzr1t_l9r_go_relaxed.owl	kievitone-hydrate hydro-lyase activity|KHase activity|kievitone-hydrate hydro-lyase (kievitone-forming)				EC:4.2.1.95|KEGG_REACTION:R03622|RHEA:23604|MetaCyc:KIEVITONE-HYDRATASE-RXN									molecular_function											owl:Class	
GO:0007370	biolink:NamedThing	ventral furrow formation	Formation of a ventral indentation (furrow) from the blastoderm epithelium, which is internalized to form a tube in the interior of the embryo, marking the start of gastrulation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0018824	biolink:NamedThing	(hydroxyamino)benzene mutase activity	Catalysis of the reaction: (hydroxyamino)benzene = 2-aminophenol.	tmpzr1t_l9r_go_relaxed.owl	HAB mutase activity|hydroxylaminobenzene mutase activity|hydroxylaminobenzene hydroxymutase activity|(hydroxyamino)benzene hydroxymutase activity				RHEA:19245|UM-BBD_reactionID:r0304|MetaCyc:5.4.4.1-RXN									molecular_function											owl:Class	
GO:0008084	biolink:NamedThing	imaginal disc growth factor receptor binding	Binding to an imaginal disc growth factor receptor.	tmpzr1t_l9r_go_relaxed.owl	imaginal disc growth factor													molecular_function											owl:Class	
GO:0043023	biolink:NamedThing	ribosomal large subunit binding	Binding to a large ribosomal subunit.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0019327	biolink:NamedThing	lead sulfide oxidation	The chemical reactions and pathways resulting in the conversion of lead sulfide to lead sulfate.	tmpzr1t_l9r_go_relaxed.owl	oxidation of lead sulfide|oxidation of galena|lead sulphide oxidation				MetaCyc:P301-PWY									biological_process											owl:Class	
GO:0003862	biolink:NamedThing	3-isopropylmalate dehydrogenase activity	Catalysis of the reaction: 3-carboxy-2-hydroxy-4-methylpentanoate + NAD+ = 3-carboxy-4-methyl-2-oxopentanoate + NADH + H+.	tmpzr1t_l9r_go_relaxed.owl	(2R,3S)-3-isopropylmalate:NAD+ oxidoreductase activity|IPMDH|beta-isopropylmalate dehydrogenase activity|3-carboxy-2-hydroxy-4-methylpentanoate:NAD+ oxidoreductase activity|beta-isopropylmalic enzyme|beta-IPM dehydrogenase activity|threo-Ds-3-isopropylmalate dehydrogenase activity|IMDH activity				MetaCyc:3-ISOPROPYLMALDEHYDROG-RXN|EC:1.1.1.85|RHEA:32271									molecular_function											owl:Class	
GO:0045060	biolink:NamedThing	negative thymic T cell selection	The process of elimination of immature T cells in the thymus which react strongly with self-antigens.	tmpzr1t_l9r_go_relaxed.owl	negative thymic T lymphocyte selection|negative thymic T-cell selection|negative thymic T-lymphocyte selection													biological_process											owl:Class	
GO:0047082	biolink:NamedThing	3,9-dihydroxypterocarpan 6a-monooxygenase activity	Catalysis of the reaction: (6aR,11aR)-3,9-dihydroxypterocarpan + H(+) + NADPH + O(2) = (6aS,11aS)-3,6a,9-trihydroxypterocarpan + H(2)O + NADP(+). (6aS,11aS)-3,6a,9-trihydroxypterocarpan is also known as (-)-glycinol.	tmpzr1t_l9r_go_relaxed.owl	3,9-dihydroxypterocarpan 6alpha-monooxygenase|3,9-dihydroxypterocarpan 6a-hydroxylase activity|(6aR,11aR)-3,9-dihydroxypterocarpan,NADPH:oxygen oxidoreductase (6a-hydroxylating)				KEGG_REACTION:R03452|MetaCyc:RXN-4505|EC:1.14.14.93|RHEA:15321									molecular_function											owl:Class	
GO:0089715	biolink:NamedThing	tRNA m6t6A37 methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + tRNA containing N6-threonylcarbamoyladenosine = S-adenosyl-L-homocysteine + tRNA containing N6-methylthreonylcarbamoyladenosine.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN0-7114	This activity is distinct from 'tRNA (adenine-N6-)-methyltransferase activity' (GO:0016430) in that it requires the presence of a threonylcarbamoyl modification.								molecular_function											owl:Class	
GO:0004641	biolink:NamedThing	phosphoribosylformylglycinamidine cyclo-ligase activity	Catalysis of the reaction: 2-(formamido)-N(1)-(5-phospho-D-ribosyl)acetamidine + ATP = 5-amino-1-(5-phospho-D-ribosyl)imidazole + ADP + 2 H(+) + phosphate.	tmpzr1t_l9r_go_relaxed.owl	2-(formamido)-N1-(5-phosphoribosyl)acetamidine cyclo-ligase (ADP-forming)|AIRS activity|2-(formamido)-1-N-(5-phosphoribosyl)acetamidine cyclo-ligase (ADP-forming)|phosphoribosyl-aminoimidazole synthetase activity|AIR synthetase activity|5'-aminoimidazole ribonucleotide synthetase activity|AIR synthase activity|phosphoribosylaminoimidazole synthetase activity				RHEA:23032|Reactome:R-HSA-73810|EC:6.3.3.1|KEGG_REACTION:R04208|MetaCyc:AIRS-RXN									molecular_function											owl:Class	
GO:0099610	biolink:NamedThing	action potential initiation	The initiating cycle of an action potential. In vertebrate neurons this typically occurs at an axon hillock. Not all initiated axon potentials propagate.	tmpzr1t_l9r_go_relaxed.owl	action potential triggering|action potential firing													biological_process											owl:Class	
GO:0019769	biolink:NamedThing	low-affinity IgE receptor activity	Combining with low affinity with an immunoglobulin of the IgE isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	low affinity IgE receptor activity|low affinity Fc receptor activity													molecular_function											owl:Class	
GO:0051210	biolink:NamedThing	isotropic cell growth	The process in which a cell irreversibly increases in size uniformly in all directions. In general, a rounded cell morphology reflects isotropic cell growth.	tmpzr1t_l9r_go_relaxed.owl	uniform cell growth													biological_process											owl:Class	
GO:0004937	biolink:NamedThing	alpha1-adrenergic receptor activity	Combining with epinephrine or norepinephrine to initiate a change in cell activity via activation of a G protein, with pharmacological characteristics of alpha1-adrenergic receptors; the activity involves transmitting the signal to the Gq alpha subunit of a heterotrimeric G protein.	tmpzr1t_l9r_go_relaxed.owl	alpha1 adrenoceptor													molecular_function											owl:Class	
GO:0008140	biolink:NamedThing	cAMP response element binding protein binding	Binding to a cAMP response element binding protein (a CREB protein).	tmpzr1t_l9r_go_relaxed.owl	CBP|3',5'-cAMP response element binding protein binding|CREB binding|cyclic AMP response element binding protein binding|adenosine 3',5'-cyclophosphate response element binding protein binding|3',5' cAMP response element binding protein binding													molecular_function											owl:Class	
GO:0101021	biolink:NamedThing	estrogen 2-hydroxylase activity	Catalysis of the reaction: estrogen + donor-H2 + O2 = 2-hydroxyestrogen + H2O.	tmpzr1t_l9r_go_relaxed.owl	oestrogen 2-hydroxylase activity													molecular_function											owl:Class	
GO:1904400	biolink:NamedThing	response to Thyroid stimulating hormone	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a Thyroid stimulating hormone stimulus.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-06-23T20:57:53Z					biological_process											owl:Class	
GO:0047659	biolink:NamedThing	alpha-santonin 1,2-reductase activity	Catalysis of the reaction: 1,2-dihydrosantonin + NAD(P)+ = alpha-santonin + NAD(P)H + H+.	tmpzr1t_l9r_go_relaxed.owl	a-santonin 1,2-reductase activity|1,2-dihydrosantonin:NAD(P)+ 1,2-oxidoreductase activity				EC:1.3.1.47|MetaCyc:ALPHA-SANTONIN-12-REDUCTASE-RXN									molecular_function											owl:Class	
GO:0035841	biolink:NamedThing	new growing cell tip	A cell tip that was newly formed at the last cell division, and that has started to grow after the cell has activated bipolar cell growth (i.e. in which new end take-off, NETO, has taken place). New end take-off is when monopolar cells initiate bipolar growth.	tmpzr1t_l9r_go_relaxed.owl	post-new end take-off new cell tip|post-NETO new cell tip|post-NETO new cell end|new cell tip after activation of bipolar cell growth							bf	2011-05-06T01:35:07Z					cellular_component											owl:Class	
GO:0019125	biolink:NamedThing	peptidyl-phenylalanine racemization	The racemization of peptidyl-phenylalanine.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0194							GO:0018371|GO:0018089		biological_process											owl:Class	
GO:0031544	biolink:NamedThing	peptidyl-proline 3-dioxygenase activity	Catalysis of the reaction: peptidyl L-proline + 2-oxoglutarate + O2 = peptidyl trans-3-hydroxy-L-proline + succinate + CO2.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1902198	biolink:NamedThing	3-methylbut-2-enoyl-CoA(4-) metabolic process	The chemical reactions and pathways involving 3-methylbut-2-enoyl-CoA(4-).	tmpzr1t_l9r_go_relaxed.owl	3-methylbut-2-enoyl-CoA(4-) metabolism							ms	2013-06-06T09:56:11Z					biological_process											owl:Class	
GO:0140569	biolink:NamedThing	extraction of mislocalized protein from ER membrane	The removal of a mislocalized protein from the endoplasmic reticulum (ER) membrane.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/20237						pg	2020-12-15T07:36:46Z					biological_process											owl:Class	
GO:0004572	biolink:NamedThing	mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity	Catalysis of the hydrolysis of the terminal (1->3)- and (1->6)-linked alpha-D-mannose residues in the mannosyl-oligosaccharide Man(5)(GlcNAc)(3).	tmpzr1t_l9r_go_relaxed.owl	mannosyl-oligosaccharide (1->3/6)-alpha-mannosidase activity|GlcNAc transferase I-dependent alpha1,3[alpha1,6]mannosidase activity|alpha-(1,3/6)-mannosidase activity|ManII activity|exo-1,3-1,6-alpha-mannosidase activity|alpha-mannosidase II|mannosidase II activity|mannosyl-oligosaccharide (1->3)-(1->6)-alpha-mannosidase activity|mannosyl-oligosaccharide (1->3,6)-alpha-mannosidase activity|alpha-D-mannosidase II|Golgi alpha-mannosidase II|1,3-(1,6-)mannosyl-oligosaccharide alpha-D-mannohydrolase activity				Reactome:R-HSA-975814|MetaCyc:3.2.1.114-RXN|RHEA:56052|EC:3.2.1.114									molecular_function											owl:Class	
GO:0018357	biolink:NamedThing	protein-phycourobilin linkage via phycourobilin-bis-L-cysteine	The linkage of the chromophore phycourobilin to phycoerythrins via phycourobilin-bis-L-cysteine.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0260							GO:0018383		biological_process											owl:Class	
GO:0047350	biolink:NamedThing	glucuronate-1-phosphate uridylyltransferase activity	Catalysis of the reaction: 1-phospho-alpha-D-glucuronate + UTP = diphosphate + UDP-alpha-D-glucuronate.	tmpzr1t_l9r_go_relaxed.owl	UTP:1-phospho-alpha-D-glucuronate uridylyltransferase activity|UTP:glucuronate-1-phosphate uridylyltransferase activity|UDP-glucuronic acid pyrophosphorylase activity|UDP-D-glucuronic acid pyrophosphorylase activity|uridine diphosphoglucuronic pyrophosphorylase activity|UDP-glucuronate pyrophosphorylase activity				RHEA:16325|KEGG_REACTION:R01381|MetaCyc:2.7.7.44-RXN|EC:2.7.7.44									molecular_function											owl:Class	
GO:0035706	biolink:NamedThing	T-helper 1 cell chemotaxis	The directed movement of a T-helper 1 cell in response to an external stimulus.	tmpzr1t_l9r_go_relaxed.owl	Th1 cell chemotaxis							bf	2011-03-02T02:36:49Z					biological_process											owl:Class	
GO:0004633	biolink:NamedThing	phosphopantothenoylcysteine decarboxylase activity	Catalysis of the reaction: N-[(R)-4-phosphonatopantothenoyl]-L-cysteinate + H(+) = CO(2) + pantetheine 4'-phosphate.	tmpzr1t_l9r_go_relaxed.owl	N-((R)-4'-phosphopantothenoyl)-L-cysteine carboxy-lyase activity|N-[(R)-4'-phosphopantothenoyl]-L-cysteine carboxy-lyase activity|4-phosphopantothenoyl-L-cysteine decarboxylase activity|PPC-decarboxylase activity|N-[(R)-4'-phosphopantothenoyl]-L-cysteine carboxy-lyase (pantotheine-4'-phosphate-forming)|4-phosphopantotheoylcysteine decarboxylase activity				MetaCyc:P-PANTOCYSDECARB-RXN|EC:4.1.1.36|KEGG_REACTION:R03269|RHEA:16793|Reactome:R-HSA-196840									molecular_function											owl:Class	
GO:0048717	biolink:NamedThing	anterior cibarial plate morphogenesis	The process in which the anatomical structures of the anterior cibarial plate are generated and organized.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0035198	biolink:NamedThing	miRNA binding	Binding to a microRNA, a 21-23 nucleotide RNA that is processed from a stem-loop RNA precursor (pre-miRNA) that is encoded within plant and animal genomes.	tmpzr1t_l9r_go_relaxed.owl	microRNA binding													molecular_function											owl:Class	
GO:1990431	biolink:NamedThing	priRNA 3'-end processing	The process of forming the mature 3' end of a priRNA molecule.	tmpzr1t_l9r_go_relaxed.owl	priRNA 3' end processing|primal small RNA 3'-end processing							jl	2014-07-29T15:34:19Z					biological_process											owl:Class	
GO:0042842	biolink:NamedThing	D-xylose biosynthetic process	The chemical reactions and pathways resulting in the formation of D-xylose, a naturally occurring plant polysaccharide.	tmpzr1t_l9r_go_relaxed.owl	D-xylose anabolism|D-xylose biosynthesis|D-xylose synthesis|D-xylose formation													biological_process											owl:Class	
GO:0061688	biolink:NamedThing	glycolytic process via Entner-Doudoroff Pathway	A glycolytic process in which the glucose is catabolized to pyruvate by first entering the Entner-Doudoroff pathway to yield pyruvate and glyceraldehyde-3-phosphate. The glyceraldehyde-3-phosphate is subsequently converted to pyruvate by the core glycolytic enzymes.	tmpzr1t_l9r_go_relaxed.owl	gluconate pathway							dph	2015-03-12T14:39:00Z					biological_process											owl:Class	
GO:0030367	biolink:NamedThing	interleukin-17 receptor binding	Binding to an interleukin-17 receptor.	tmpzr1t_l9r_go_relaxed.owl	IL-17|interleukin-17 receptor ligand													molecular_function											owl:Class	
GO:0090586	biolink:NamedThing	protein-phosphocysteine-N-acetylglucosamine phosphotransferase system transporter activity	Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein S-phosphocysteine + N-acetylglucosamine (out) = protein cysteine + N-acetylglucosamine-6-phosphate (in).	tmpzr1t_l9r_go_relaxed.owl								tb	2014-06-04T16:22:31Z					molecular_function											owl:Class	
GO:0044066	biolink:NamedThing	modification by symbiont of host cell nucleus	The process in which a symbiont organism effects a change in the structure or function of its host cell nucleus.	tmpzr1t_l9r_go_relaxed.owl	modification by symbiont of host nucleus|modification of host nucleus by symbiont|modification of host cell nucleus by symbiont													biological_process											owl:Class	
GO:0103074	biolink:NamedThing	glucose-6-phosphate 3-dehydrogenase activity	Catalysis of the reaction: NAD + D-glucopyranose 6-phosphate = NADH + H+ + 3-dehydro-D-glucose 6-phosphate.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN8J2-136|EC:1.1.1.361|RHEA:37547									molecular_function											owl:Class	
GO:0046684	biolink:NamedThing	response to pyrethroid	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pyrethroid stimulus. Pyrethroids are a group of growth regulators, analogous to insect juvenile hormones, that interfere with the development of insect larvae and are used in the control of insects that are harmful in the adult stage.	tmpzr1t_l9r_go_relaxed.owl	pyrethroid resistance|pyrethroid susceptibility/resistance													biological_process											owl:Class	
GO:0050162	biolink:NamedThing	oxalate oxidase activity	Catalysis of the reaction: 2 H(+) + O(2) + oxalate = 2 CO(2) + H(2)O(2).	tmpzr1t_l9r_go_relaxed.owl	aero-oxalo dehydrogenase activity|oxalate:oxygen oxidoreductase activity|oxalic acid oxidase activity				EC:1.2.3.4|KEGG_REACTION:R00273|RHEA:21880|MetaCyc:OXALATE-OXIDASE-RXN									molecular_function											owl:Class	
GO:0075139	biolink:NamedThing	response to host iron concentration	Any process that results in a change in state or activity of the symbiont or its cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detecting iron concentration in its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	response of symbiont to host iron concentration					Note that this term is used to annotate gene products of the symbiont.								biological_process											owl:Class	
GO:0080023	biolink:NamedThing	3R-hydroxyacyl-CoA dehydratase activity	Catalysis of the reaction: 3R-hydroxyacyl-CoA = 2E-enoyl-CoA + H2O.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-5676637									molecular_function											owl:Class	
GO:0044015	biolink:NamedThing	histone acetyltransferase activity (H2B-K12 specific)	Catalysis of the reaction: acetyl-CoA + histone H2B L-lysine (position 12) = CoA + histone H2B N6-acetyl-L-lysine (position 12).	tmpzr1t_l9r_go_relaxed.owl	histone lysine N-acetyltransferase activity (H2B-K12 specific)													molecular_function											owl:Class	
GO:0021927	biolink:NamedThing	deep nuclear neuron precursor proliferation	The multiplication or reproduction of neuroblasts that will give rise to deep nuclear neurons.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0033538	biolink:NamedThing	ajugose biosynthetic process using galactan:galactan galactosyltransferase	The chemical reactions and pathways resulting in the formation of ajugose, the hexasaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside, by a pathway in which galactan:galactan galactosyltransferase catalyzes chain elongation by transferring the alpha-galactosyl residue of one raffinose-family oligosaccharide to another.	tmpzr1t_l9r_go_relaxed.owl	ajugose synthesis using galactan:galactan galactosyltransferase|ajugose anabolism using galactan:galactan galactosyltransferase|ajugose formation using galactan:galactan galactosyltransferase|ajugose biosynthesis using galactan:galactan galactosyltransferase				MetaCyc:PWY-5343									biological_process											owl:Class	
GO:0050387	biolink:NamedThing	urethanase activity	Catalysis of the reaction: H(2)O + H(+) + urethane = CO(2) + ethanol + NH(4)(+).	tmpzr1t_l9r_go_relaxed.owl	urethane hydrolase activity|urethane amidohydrolase (decarboxylating)				MetaCyc:URETHANASE-RXN|KEGG_REACTION:R02359|EC:3.5.1.75|RHEA:21372									molecular_function											owl:Class	
GO:1990955	biolink:NamedThing	G-rich single-stranded DNA binding	Binding to G-rich, single-stranded DNA.	tmpzr1t_l9r_go_relaxed.owl								hjd	2016-05-13T17:44:28Z					molecular_function											owl:Class	
GO:0120145	biolink:NamedThing	protein localization to basal ectoplasmic specialization	A process in which a protein is transported to, or maintained in, a location within a basal ectoplasmic specialization.	tmpzr1t_l9r_go_relaxed.owl	protein localization in basal ectoplasmic specialization|protein localisation to basal ectoplasmic specialization|protein localisation in basal ectoplasmic specialization							krc	2018-03-27T20:16:09Z					biological_process											owl:Class	
GO:0052626	biolink:NamedThing	benzoate amino acid synthetase activity	Catalysis of the reaction: benzoate + ATP + amino acid = benzoyl amino acid conjugate + AMP + diphosphate.	tmpzr1t_l9r_go_relaxed.owl	benzoyl amino acid synthetase activity													molecular_function											owl:Class	
GO:0034901	biolink:NamedThing	endosulfan hydroxyether dehydrogenase activity	Catalysis of the reaction: endosulfan hydroxyether = endosulfan lactone + 2 H+ + 2 e-.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r1411									molecular_function											owl:Class	
GO:0102416	biolink:NamedThing	quercetin gentiotrioside 1,6-glucosyltransferase activity	Catalysis of the reaction: quercetin-3-gentiotrioside + UDP-alpha-D-glucose <=> quercetin-3-gentiotetraside + UDP + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-13799									molecular_function											owl:Class	
GO:0016914	biolink:NamedThing	follicle-stimulating hormone complex	A gonadotrophic glycoprotein hormone secreted, in mammals, by the anterior pituitary gland; consists of alpha and beta subunits, the latter of which confers hormonal specificity.	tmpzr1t_l9r_go_relaxed.owl	FSH complex|follicle stimulating hormone complex													cellular_component											owl:Class	
GO:0030732	biolink:NamedThing	methionine S-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + L-methionine = S-adenosyl-L-homocysteine + S-methyl-L-methionine.	tmpzr1t_l9r_go_relaxed.owl	S-adenosylmethionine transmethylase activity|S-adenosyl-L-methionine:L-methionine S-methyltransferase activity|S-adenosyl methionine:methionine methyl transferase activity|S-adenosylmethionine-methionine methyltransferase activity|methionine methyltransferase activity				RHEA:13761|EC:2.1.1.12|MetaCyc:METHIONINE-S-METHYLTRANSFERASE-RXN									molecular_function											owl:Class	
GO:0016554	biolink:NamedThing	cytidine to uridine editing	The conversion of a cytosine residue to uridine in an RNA molecule by deamination.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0050621	biolink:NamedThing	tryptophan alpha,beta-oxidase activity	Catalysis of the reaction: L-tryptophan + O(2) = alpha,beta-didehydrotryptophan + H(2)O(2) + H(+).	tmpzr1t_l9r_go_relaxed.owl	L-tryptophan 2',3'-oxidase activity|L-tryptophan alpha,beta-dehydrogenase activity|L-tryptophan:oxygen alpha,beta-oxidoreductase activity|tryptophan a,b-oxidase activity				EC:1.3.3.10|KEGG_REACTION:R05317|MetaCyc:1.4.3.17-RXN|RHEA:19901	Note that this was EC:1.4.3.17.								molecular_function											owl:Class	
GO:0097110	biolink:NamedThing	scaffold protein binding	Binding to a scaffold protein. Scaffold proteins are crucial regulators of many key signaling pathways. Although not strictly defined in function, they are known to interact and/or bind with multiple members of a signaling pathway, tethering them into complexes.	tmpzr1t_l9r_go_relaxed.owl								pr	2011-07-28T05:16:53Z					molecular_function											owl:Class	
GO:0009949	biolink:NamedThing	polarity specification of anterior/posterior axis	Any process resulting in the establishment of polarity along the anterior/posterior axis.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0031773	biolink:NamedThing	kisspeptin receptor binding	Binding to a kisspeptin receptor.	tmpzr1t_l9r_go_relaxed.owl	G-protein coupled receptor 54 binding|metastin receptor binding|hOT7T175 receptor binding|hypogonadotropin-1 receptor binding|KiSS-1 receptor binding|kisspeptin receptor ligand													molecular_function											owl:Class	
GO:0070061	biolink:NamedThing	fructose binding	Binding to the D- or L-enantiomer of fructose, the ketohexose arabino-hex-2-ulose.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0052098	biolink:NamedThing	formation by host of specialized structure for nutrient acquisition from symbiont	The assembly by an organism of a cellular component or anatomical structure for the purpose of obtaining nutrients from a symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0038059	biolink:NamedThing	IKKalpha-IKKalpha complex	A homodimeric protein complex containing two IkappaB kinase (IKK) alpha subunits.	tmpzr1t_l9r_go_relaxed.owl	IkappaB kinase-alpha homodimer|IKKalpha homodimeric complex|IKKalpha-IKKalpha protein complex|IKKalpha homodimer|IkappaB kinase alpha homodimer							bf	2012-01-10T09:29:53Z					cellular_component											owl:Class	
GO:0070207	biolink:NamedThing	protein homotrimerization	The formation of a protein homotrimer, a macromolecular structure consisting of three noncovalently associated identical subunits.	tmpzr1t_l9r_go_relaxed.owl	protein homotrimer biosynthetic process|protein homotrimer biosynthesis|protein homotrimer formation|protein homotrimer assembly													biological_process											owl:Class	
GO:0008473	biolink:NamedThing	ornithine cyclodeaminase activity	Catalysis of the reaction: L-ornithine = L-proline + NH(4)(+).	tmpzr1t_l9r_go_relaxed.owl	ornithine cyclase activity|ornithine cyclase (deaminating) activity|OCD activity|L-ornithine ammonia-lyase (cyclizing)|L-ornithine ammonia-lyase (cyclizing; L-proline-forming)				EC:4.3.1.12|KEGG_REACTION:R00671|RHEA:24368|MetaCyc:ORNITHINE-CYCLODEAMINASE-RXN	Note that cyclodeaminases are lyases according to EC, whereas deaminases are hydrolases.								molecular_function											owl:Class	
GO:0102854	biolink:NamedThing	1-18:2-2-18:1-phosphatidylcholine desaturase activity	Catalysis of the reaction: 1-18:2-2-18:1-phosphatidylcholine + O2 + a reduced electron acceptor <=> 1-18:3-2-18:1-phosphatidylcholine + 2 H2O + an oxidized electron acceptor.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-8321									molecular_function											owl:Class	
GO:0047527	biolink:NamedThing	2,3-dihydroxybenzoate-serine ligase activity	Catalysis of the reaction: ATP + 2,3-dihydroxybenzoate + L-serine = products of ATP breakdown + N-(2,3-dihydroxybenzoyl)-L-serine.	tmpzr1t_l9r_go_relaxed.owl	2,3-dihydroxybenzoylserine synthetase activity|N-(2,3-dihydroxybenzoyl)-serine synthetase activity|2,3-dihydroxybenzoate:L-serine ligase activity				RHEA:30571|EC:6.3.2.14|MetaCyc:23-DIHYDROXYBENZOATE--SERINE-LIGASE-RXN									molecular_function											owl:Class	
GO:0031387	biolink:NamedThing	MPF complex	A complex consisting of a Cdc2-class (also known as Cdc28) cyclin-dependent kinase and an M-phase cyclin such as S. pombe Cdc13. The MPF complex phosphorylates and activates the anaphase promoting complex (APC).	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:1990472	biolink:NamedThing	piRNA dual-strand cluster binding	Binding to dual-strand piRNA clusters, double-stranded DNA regions that give rise to PIWI-interacting RNAs (piRNAs) where piRNAs originate from both DNA strands via noncanonical transcription.	tmpzr1t_l9r_go_relaxed.owl						An example of this is rhi in Drosophila melanogaster (Q7JXA8) in PMID:24906153 (inferred from direct assay).		bhm	2014-08-29T14:50:54Z					molecular_function											owl:Class	
GO:0070584	biolink:NamedThing	mitochondrion morphogenesis	The process in which the anatomical structures of a mitochondrion are generated and organized.	tmpzr1t_l9r_go_relaxed.owl						Note that this term is intended for annotation of gene products involved in mitochondrial shape changes associated with development; an example is the morphogenesis of the Nebenkern during spermatogenesis.		mah	2009-04-24T10:54:19Z					biological_process											owl:Class	
GO:0043701	biolink:NamedThing	cyanosome	A tissue-specific, membrane-bounded cytoplasmic organelle within which an unknown blue pigment is localized. Cyanosomes are synthesized in cyanophores and are blue in appearance.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0102757	biolink:NamedThing	NADPH phosphatase activity	Catalysis of the reaction: NADPH + H2O = NADH + hydrogenphosphate.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-7703|RHEA:60664									molecular_function											owl:Class	
GO:0030944	biolink:NamedThing	DDEL sequence binding	Binding to a KDEL sequence, the C terminus tetrapeptide sequence Asp-Asp-Glu-Leu found in proteins that are to be retained in the endoplasmic reticulum.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0003864	biolink:NamedThing	3-methyl-2-oxobutanoate hydroxymethyltransferase activity	Catalysis of the reaction: 5,10-methylenetetrahydrofolate + 3-methyl-2-oxobutanoate = tetrahydrofolate + 2-dehydropantoate.	tmpzr1t_l9r_go_relaxed.owl	ketopantoate hydroxymethyltransferase activity|oxopantoate hydroxymethyltransferase activity|5,10-methylene tetrahydrofolate:alpha-ketoisovalerate hydroxymethyltransferase activity|5,10-methylenetetrahydrofolate:3-methyl-2-oxobutanoate hydroxymethyltransferase activity|dehydropantoate hydroxymethyltransferase activity|alpha-ketoisovalerate hydroxymethyltransferase activity				RHEA:11824|EC:2.1.2.11|MetaCyc:3-CH3-2-OXOBUTANOATE-OH-CH3-XFER-RXN									molecular_function											owl:Class	
GO:0044222	biolink:NamedThing	anammoxosome	An intracytoplasmic membrane-bounded compartment in anaerobic ammonium oxidation (anammox) bacteria, is the site of anammox catabolism.	tmpzr1t_l9r_go_relaxed.owl								jl	2009-11-12T04:03:24Z					cellular_component											owl:Class	
GO:0102581	biolink:NamedThing	cyanidin 3-O-glucoside-p-coumaroyltransferase activity	Catalysis of the reaction: cyanidin 3-O-beta-D-glucoside betaine + 4-coumaryl-CoA + H+ <=> cyanidin 3-O-(6-O-(E)-4-coumaroyl-beta-D-glucoside) + coenzyme A.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-15327									molecular_function											owl:Class	
GO:0005170	biolink:NamedThing	neurotrophin TRKC receptor binding	Binding to a neurotrophin TRKC receptor.	tmpzr1t_l9r_go_relaxed.owl	neurotrophin TRKC receptor ligand													molecular_function											owl:Class	
GO:0019553	biolink:NamedThing	glutamate catabolic process via L-citramalate	The chemical reactions and pathways resulting in the breakdown of glutamate, via the intermediate L-citramalate.	tmpzr1t_l9r_go_relaxed.owl	glutamate degradation via L-citramalate|glutamate breakdown via L-citramalate				MetaCyc:GLUDEG-II-PWY									biological_process											owl:Class	
GO:0060577	biolink:NamedThing	pulmonary vein morphogenesis	The process in which the anatomical structure of the pulmonary venous blood vessels are generated and organized. Pulmonary veins are blood vessels that transport blood from the lungs to the heart.	tmpzr1t_l9r_go_relaxed.owl	pulmonary venous blood vessel morphogenesis							dph	2009-05-06T08:44:04Z					biological_process											owl:Class	
GO:0046737	biolink:NamedThing	induction of cell-mediated immune response in host by virus	The intentional, virally-encoded stimulation of a cell-mediated host defense response to viral infection.	tmpzr1t_l9r_go_relaxed.owl	active induction of cell-mediated immune response in host by virus|active viral induction of cell-mediated immune response in host													biological_process											owl:Class	
GO:0071185	biolink:NamedThing	protocadherin-alpha-v4-protocadherin-gamma-a3 complex	A protein complex that contains the cell adhesion molecules protocadherin-alpha-v4 and protocadherin-gamma-a3, and is involved in the regulation of protein localization to the plasma membrane.	tmpzr1t_l9r_go_relaxed.owl	Pcdhga1-Pcdhga3 complex							mah	2009-11-23T04:16:47Z					cellular_component											owl:Class	
GO:0106355	biolink:NamedThing	4-hydroxybenzoate 3-monooxygenase [NADH] activity	Catalysis of the reaction: 4-hydroxybenzoate + H+ + NADH + O2 = 3,4-dihydroxybenzoate + H2O + NAD+.	tmpzr1t_l9r_go_relaxed.owl					RHEA:19473			hjd	2021-02-02T05:51:36Z					molecular_function											owl:Class	
GO:0071540	biolink:NamedThing	eukaryotic translation initiation factor 3 complex, eIF3e	An eukaryotic translation initiation factor 3 complex that contains the PCI-domain protein eIF3e.	tmpzr1t_l9r_go_relaxed.owl	eIF3e-containing eukaryotic translation initiation factor 3 complex							mah	2010-01-12T02:20:24Z					cellular_component											owl:Class	
GO:0004370	biolink:NamedThing	glycerol kinase activity	Catalysis of the reaction: ATP + glycerol = sn-glycerol 3-phosphate + ADP + 2 H(+).	tmpzr1t_l9r_go_relaxed.owl	glycerol kinase (phosphorylating)|ATP:glycerol 3-phosphotransferase activity|GK|glycerokinase activity|glyceric kinase activity|ATP:glycerol-3-phosphotransferase activity				RHEA:21644|Reactome:R-HSA-75887|KEGG_REACTION:R00847|EC:2.7.1.30|MetaCyc:GLYCEROL-KIN-RXN									molecular_function											owl:Class	
GO:0090535	biolink:NamedThing	WICH complex	An ISWI complex that contains an ATPase subunit of the ISWI family (specifically SNF2H in mammals, which contain two ISWI homologs) and WSTF (Williams Syndrome Transcription Factor). WICH plays roles in regulation of RNAP I and III transcription and in DNA replication and repair.	tmpzr1t_l9r_go_relaxed.owl								tb	2013-02-11T14:07:14Z					cellular_component											owl:Class	
GO:0002337	biolink:NamedThing	B-1a B cell differentiation	The process in which B cells acquire the specialized features of B-1a B cells. B-1a B cells are B-1 cells that express CD5 and arise from fetal liver precursors.	tmpzr1t_l9r_go_relaxed.owl	B-1a B-lymphocyte differentiation|B-1a B lymphocyte differentiation|B-1a B cell development|B-1a B-cell differentiation					Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.								biological_process											owl:Class	
GO:0036312	biolink:NamedThing	phosphatidylinositol 3-kinase regulatory subunit binding	Binding to a regulatory subunit of phosphatidylinositol 3-kinase. The regulatory subunit associates with the catalytic subunit to regulate both its activity and subcellular location.	tmpzr1t_l9r_go_relaxed.owl	p85 binding|PI3K regulatory subunit binding							bf	2012-08-16T10:58:45Z					molecular_function											owl:Class	
GO:0034857	biolink:NamedThing	2-(methylthio)benzothiazole monooxygenase activity	Catalysis of the reaction: 2-(methylthio)benzothiazole + 1/2 O2 = 2-(methylsulfinyl)benzothiazole.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r1287									molecular_function											owl:Class	
GO:0033919	biolink:NamedThing	glucan 1,3-alpha-glucosidase activity	Catalysis of the hydrolysis of terminal (1->3)-alpha-D-glucosidic links in 1,3-alpha-D-glucans.	tmpzr1t_l9r_go_relaxed.owl	1,3-alpha-D-glucan 3-glucohydrolase activity|exo-1,3-alpha-glucanase activity				Reactome:R-HSA-9694364|Reactome:R-HSA-9683663|Reactome:R-HSA-532667|Reactome:R-HSA-548890|EC:3.2.1.84|MetaCyc:3.2.1.84-RXN									molecular_function											owl:Class	
GO:0046429	biolink:NamedThing	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase activity	Catalysis of the reaction: (E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate + H2O + 2 oxidized ferredoxin = 2-C-methyl-D-erythritol 2,4-cyclodiphosphate + 2 reduced ferredoxin.	tmpzr1t_l9r_go_relaxed.owl	1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase activity|(E)-4-hydroxy-3-methylbut-2-en-1-yl-diphosphate:oxidized ferredoxin oxidoreductase activity|(E)-4-hydroxy-3-methylbut-2-enyl diphosphate synthase activity|1-hydroxy-2-methyl-2-butenyl 4-diphosphate synthase activity				EC:1.17.7.1|KEGG_REACTION:R08689|MetaCyc:RXN0-882|RHEA:26119									molecular_function											owl:Class	
GO:0042621	biolink:NamedThing	poly(3-hydroxyalkanoate) biosynthetic process	The chemical reactions and pathways resulting in the formation of poly(3-hydroxyalkanoates), polyesters of 3-hydroxyacids produced as intracellular granules by a large variety of bacteria.	tmpzr1t_l9r_go_relaxed.owl	PHA biosynthesis|PHA biosynthetic process|poly(3-hydroxyalkanoate) biosynthesis|poly(3-hydroxyalkanoate) synthesis|poly(3-hydroxyalkanoate) formation|poly(3-hydroxyalkanoate) anabolism													biological_process											owl:Class	
GO:0010267	biolink:NamedThing	production of ta-siRNAs involved in RNA interference	Cleavage of double-stranded RNA to form trans-acting small interfering RNA molecules (siRNAs) of 21-23 nucleotides. ta-siRNAs arise from PolII genes and function like miRNAs to guide cleavage of target mRNAs.	tmpzr1t_l9r_go_relaxed.owl	RNA interference, production of ta-siRNAs													biological_process											owl:Class	
GO:0106389	biolink:NamedThing	ecdysteroid 22-kinase activity	Catalysis of the reaction: an ecdysteroid + ATP = an ecdysteroid 22-phosphate + ADP + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-14755			hjd	2021-07-13T14:37:23Z					molecular_function											owl:Class	
GO:0008496	biolink:NamedThing	mannan endo-1,6-alpha-mannosidase activity	Catalysis of the random hydrolysis of (1->6)-alpha-D-mannosidic linkages in unbranched (1->6)-mannans.	tmpzr1t_l9r_go_relaxed.owl	mannan endo-1,6-beta-mannosidase activity|endo-alpha-D-mannosidase activity|exo-1,6-beta-mannanase activity|1,6-alpha-D-mannan mannanohydrolase activity|endo-1,6-beta-mannanase activity|1,6-beta-D-mannan mannanohydrolase activity|endo-alpha-1->6-D-mannanase activity				Reactome:R-HSA-6799581|MetaCyc:3.2.1.101-RXN|EC:3.2.1.101									molecular_function											owl:Class	
GO:0035885	biolink:NamedThing	exochitinase activity	Catalysis of the hydrolysis of terminal 1,4-beta-linkages of N-acetyl-D-glucosamine (GlcNAc) polymers of chitin and chitodextrins. Typically, exochitinases progressively cleave off two subunits from the reducing or non-reducing ends of the chitin chain.	tmpzr1t_l9r_go_relaxed.owl					RHEA:50672|MetaCyc:RXN-12309			bf	2011-06-08T11:13:58Z					molecular_function											owl:Class	
GO:0031249	biolink:NamedThing	denatured protein binding	Binding to a denatured protein.	tmpzr1t_l9r_go_relaxed.owl						Note that this term should not be confused with 'unfolded protein binding ; GO:0051082', which usually refers to proteins that have not yet folded into their active states. Denatured proteins once were in their correct functional conformations, but have become incorrectly folded, and often form aggregates.								molecular_function											owl:Class	
GO:0018508	biolink:NamedThing	cis-1,2-dihydroxycyclohexa-3,5-diene-1-carboxylate dehydrogenase activity	Catalysis of the reaction: cis-1,2-dihydroxycyclohexa-3,5-diene-1-carboxylate + NAD+ = catechol + CO2 + NADH + H+.	tmpzr1t_l9r_go_relaxed.owl	benzoate cis-diol dehydrogenase activity				UM-BBD_enzymeID:e0219									molecular_function											owl:Class	
GO:0009588	biolink:NamedThing	UV-A, blue light phototransduction	The sequence of reactions within a cell required to convert absorbed photons from UV-A or blue light into a molecular signal; the UV-A, blue light range is defined as having a wavelength within the range of 315 to 400 nm.	tmpzr1t_l9r_go_relaxed.owl	violet-sensitive opsin|blue-sensitive opsin|short-wave-sensitive opsin													biological_process											owl:Class	
GO:1990140	biolink:NamedThing	MPT synthase complex	A heterodimeric protein complex which catalyses sulfur transfer from the sulfur carrier subunit of MPT synthase to precursor Z to synthesize MPT as part of molybdopterin cofactor (Moco) biosynthesis. In E. coli the subunits are MoaE and MoaD; in human, MOCS2B and MOCS2A. Moco biosynthesis and its constituent molecules are evolutionarily conserved.	tmpzr1t_l9r_go_relaxed.owl	molybdopterin cofactor (Moco) biosynthesis sulfurtransferase complex							pr	2013-07-11T08:32:29Z					cellular_component											owl:Class	
GO:0102141	biolink:NamedThing	[chondroitin sulfate]-D-glucuronyl 2-O-sulfotransferase activity	Catalysis of the reaction: 3'-phosphonato-5'-adenylyl sulfate + [chondroitin-sulfate]-beta-D-glucuronate = adenosine 3',5'-bismonophosphate + [chondroitin-sulfate]-2-O-sulfo-beta-D-glucuronate.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-11560									molecular_function											owl:Class	
GO:0004587	biolink:NamedThing	ornithine-oxo-acid transaminase activity	Catalysis of the reaction: L-ornithine + a 2-oxo acid = L-glutamate 5-semialdehyde + an L-amino acid.	tmpzr1t_l9r_go_relaxed.owl	ornithine-oxo-acid aminotransferase activity|L-ornithine:alpha-ketoglutarate delta-aminotransferase activity|ornithine--ketoglutarate aminotransferase activity|ornithine--alpha-ketoglutarate aminotransferase activity|ornithine--keto acid transaminase activity|ornithine--oxo-acid transaminase activity|GabT|ornithine--2-oxoacid aminotransferase activity|ornithine delta-transaminase activity|ornithine--oxo acid aminotransferase activity|ornithine ketoacid aminotransferase activity|L-ornithine 5-aminotransferase activity|ornithine:alpha-oxoglutarate transaminase activity|L-ornithine:2-oxo-acid aminotransferase activity|ornithine--keto acid aminotransferase activity|ornithine transaminase activity|L-ornithine aminotransferase activity|ornithine aminotransferase activity|ornithine 5-aminotransferase activity|OAT				Reactome:R-HSA-70654|Reactome:R-HSA-70666|MetaCyc:ORNITHINE--OXO-ACID-AMINOTRANSFERASE-RXN|RHEA:13877|EC:2.6.1.13									molecular_function											owl:Class	
GO:0061498	biolink:NamedThing	intermediate layer of mitotic spindle pole body	Structure between the central and outer plaques of the mitotic spindle pole body.	tmpzr1t_l9r_go_relaxed.owl								dph	2012-12-11T09:17:14Z					cellular_component											owl:Class	
GO:0001634	biolink:NamedThing	pituitary adenylate cyclase-activating polypeptide receptor activity	A G protein-coupled receptor that interacts with pituitary adenylate cyclase-activating polypeptide.	tmpzr1t_l9r_go_relaxed.owl	PACAP receptor|pituitary adenylate cyclase-activating peptide receptor activity|pituitary adenylyl cyclase activating protein receptor activity|pituitary adenylate cyclase activating polypeptide receptor|pituitary adenylate cyclase activating protein receptor activity											GO:0016522		molecular_function											owl:Class	
GO:0097434	biolink:NamedThing	succinate:proton symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: succinate(out) + H+(out) = succinate(in) + H+(in).	tmpzr1t_l9r_go_relaxed.owl	succinate:hydrogen symporter activity							pr	2012-11-26T18:19:42Z					molecular_function											owl:Class	
GO:0033836	biolink:NamedThing	flavonol 7-O-beta-glucosyltransferase activity	Catalysis of the reaction: UDP-glucose + a flavonol = UDP + a flavonol 7-O-beta-D-glucoside.	tmpzr1t_l9r_go_relaxed.owl	UDP-glucose:flavonol 7-O-beta-D-glucosyltransferase activity|UDP-glucose:flavonol 7-O-glucosyltransferase activity				MetaCyc:2.4.1.237-RXN|EC:2.4.1.237|RHEA:23164									molecular_function											owl:Class	
GO:1905317	biolink:NamedThing	inferior endocardial cushion morphogenesis	The developmental process by which an inferior endocardial cushion is generated and organized.	tmpzr1t_l9r_go_relaxed.owl	ventral endocardial cushion morphogenesis							rl	2016-07-12T14:14:56Z					biological_process											owl:Class	
GO:0072493	biolink:NamedThing	host cell endosome lumen	The volume enclosed by the membranes of the host cell endosome.	tmpzr1t_l9r_go_relaxed.owl	host endosome lumen							mah	2010-12-15T11:45:53Z					cellular_component											owl:Class	
GO:0018576	biolink:NamedThing	catechol 1,2-dioxygenase activity	Catalysis of the reaction: catechol + O2 = cis,cis-muconate.	tmpzr1t_l9r_go_relaxed.owl	pyrocatechase activity|catechase activity|pyrocatechol 1,2-dioxygenase activity|catechol:oxygen 1,2-oxidoreductase activity|catechol 1,2-oxygenase activity|CD II|1,2-pyrocatechase activity|catechol-oxygen 1,2-oxidoreductase activity|CD I				UM-BBD_enzymeID:e0064|MetaCyc:CATECHOL-12-DIOXYGENASE-RXN|EC:1.13.11.1|RHEA:23852									molecular_function											owl:Class	
GO:0033134	biolink:NamedThing	ubiquitin activating enzyme binding	Binding to a ubiquitin activating enzyme, any of the E1 proteins.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0071753	biolink:NamedThing	IgM immunoglobulin complex	A protein complex composed of two identical immunoglobulin heavy chains of the IgM isotype and two identical immunoglobulin light chains, held together by disulfide bonds, and in its circulating form complexed with J chain in polymeric forms. An IgM immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.	tmpzr1t_l9r_go_relaxed.owl						Note that an IgM immunoglobulin complex has the function of antigen binding if a suitable antigen is available.		mah	2010-03-24T01:44:53Z					cellular_component											owl:Class	
GO:0043224	biolink:NamedThing	nuclear SCF ubiquitin ligase complex	A ubiquitin ligase complex, located in the nucleus, in which a cullin from the Cul1 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by a Skp1 adaptor and an F-box protein. SCF complexes are involved in targeting proteins for degradation by the proteasome. The best characterized complexes are those from yeast and mammals (with core subunits named Cdc53/Cul1, Rbx1/Hrt1/Roc1).	tmpzr1t_l9r_go_relaxed.owl	nuclear SCF complex|nuclear cullin complex|nuclear Skp1/Cul1/F-box protein complex													cellular_component											owl:Class	
GO:0043262	biolink:NamedThing	adenosine-diphosphatase activity	Catalysis of the reaction: ADP + H2O = AMP + phosphate.	tmpzr1t_l9r_go_relaxed.owl	ATP diphosphohydrolase activity|ATP-diphosphatase activity|ADPase activity|ADPase|adenosine diphosphatase activity				MetaCyc:APYRASE-RXN|RHEA:61436									molecular_function											owl:Class	
GO:0017113	biolink:NamedThing	dihydropyrimidine dehydrogenase (NADP+) activity	Catalysis of the reaction: 5,6-dihydrouracil + NADP+ = uracil + NADPH + H+.	tmpzr1t_l9r_go_relaxed.owl	dihydrouracil dehydrogenase (NADP)|DHU dehydrogenase activity|dihydrothymine dehydrogenase activity|dehydrogenase, dihydrouracil (nicotinamide adenine dinucleotide phosphate)|DPD|dihydrouracil dehydrogenase (NADP+) activity|5,6-dihydrouracil:NADP+ 5-oxidoreductase activity|4,5-dihydrothymine: oxidoreductase activity|hydropyrimidine dehydrogenase activity|DHPDH|dihydropyrimidine dehydrogenase activity				MetaCyc:1.3.1.2-RXN|Reactome:R-HSA-73585|EC:1.3.1.2|Reactome:R-HSA-73616|RHEA:18093									molecular_function											owl:Class	
GO:0047306	biolink:NamedThing	D-methionine-pyruvate transaminase activity	Catalysis of the reaction: D-methionine + pyruvate = 4-methylthio-2-oxobutanoate + L-alanine.	tmpzr1t_l9r_go_relaxed.owl	D-methionine transaminase activity|D-methionine:pyruvate aminotransferase activity|D-methionine--pyruvate aminotransferase activity|D-methionine aminotransferase activity|D-methionine-pyruvate aminotransferase activity				RHEA:23836|EC:2.6.1.41|MetaCyc:2.6.1.41-RXN|KEGG_REACTION:R03001									molecular_function											owl:Class	
GO:0032287	biolink:NamedThing	peripheral nervous system myelin maintenance	The process in which the structure and material content of mature peripheral nervous system myelin is kept in a functional state.	tmpzr1t_l9r_go_relaxed.owl	myelin maintenance in peripheral nervous system													biological_process											owl:Class	
GO:0033907	biolink:NamedThing	beta-D-fucosidase activity	Catalysis of the hydrolysis of terminal non-reducing beta-D-fucose residues in beta-D-fucosides.	tmpzr1t_l9r_go_relaxed.owl	beta-fucosidase activity|beta-D-fucoside fucohydrolase activity				MetaCyc:3.2.1.38-RXN|EC:3.2.1.38									molecular_function											owl:Class	
GO:1990731	biolink:NamedThing	UV-damage excision repair, DNA incision	A process that results in the endonucleolytic cleavage of the damaged strand of DNA immediately 5' of a UV-induced damage site, and is the first part of a DNA repair process that acts on both cyclobutane pyrimidine dimers (CPDs) and pyrimidine-pyrimidone 6-4 photoproducts (6-4PPs).	tmpzr1t_l9r_go_relaxed.owl	DNA incision involved in UVER|DNA incision involved in alternative excision repair|DNA incision involved in AER|UV-damaged DNA endonuclease-dependent excision repair, DNA incision|UVDE-dependent excision repair, DNA incision|DNA incision involved in UVDE-dependent excision repair|DNA incision involved in UV-damaged DNA endonuclease-dependent excision repair|DNA incision involved in UV-damage excision repair|nucleic acid cleavage involved in UV-damage excision repair|alternative excision repair, DNA incision							mah	2015-04-21T15:09:04Z					biological_process											owl:Class	
GO:0072347	biolink:NamedThing	response to anesthetic	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an anesthetic stimulus. An anesthetic is a substance that causes loss of feeling, awareness, or sensation.	tmpzr1t_l9r_go_relaxed.owl	response to anaesthetic							mah	2010-11-10T01:26:18Z					biological_process											owl:Class	
GO:0102039	biolink:NamedThing	alkylhydroperoxide reductase activity	Catalysis of the reaction: H2O + NAD + an alcohol <=> NADH + H+ + an organic hydroperoxide.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:R4-RXN|EC:1.11.1.26									molecular_function											owl:Class	
GO:0070913	biolink:NamedThing	Ddb1-Wdr21 complex	A heterodimeric nucleotide-excision repair complex that is involved in transcription-coupled repair. The subunits are known as Ddb1 and Wdr21 in S. pombe; Ddb1 contains a motif called the DDB-box that interacts with adaptor proteins for DDB1/cullin 4 ubiquitin ligases.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-09-09T03:47:54Z					cellular_component											owl:Class	
GO:1990084	biolink:NamedThing	DnaA-Dps complex	A protein complex that negatively regulates strand-opening at the origin of replication, thereby interfering with replication initiation. This complex is thought to be involved in the regulation of replication under oxidative stress conditions. In E. coli, this complex is composed of DnaA and Dps.	tmpzr1t_l9r_go_relaxed.owl								bhm	2013-04-30T11:50:17Z					cellular_component											owl:Class	
GO:0102489	biolink:NamedThing	GTP phosphohydrolase activity	Catalysis of the reaction: GTP + 2 H2O = GMP + 2 hydrogenphosphate + 2 H+.	tmpzr1t_l9r_go_relaxed.owl					EC:3.6.1.5|MetaCyc:RXN-14201									molecular_function											owl:Class	
GO:0008742	biolink:NamedThing	L-ribulose-phosphate 4-epimerase activity	Catalysis of the reaction: L-ribulose 5-phosphate = D-xylulose 5-phosphate.	tmpzr1t_l9r_go_relaxed.owl	L-ribulose-5-phosphate 4-epimerase|L-Ru5P|L-ru5P activity|phosphoribulose isomerase activity|AraD|ribulose phosphate 4-epimerase activity|L-ribulose 5-phosphate 4-epimerase activity				KEGG_REACTION:R05850|EC:5.1.3.4|RHEA:22368|MetaCyc:RIBULPEPIM-RXN									molecular_function											owl:Class	
GO:0002039	biolink:NamedThing	p53 binding	Binding to one of the p53 family of proteins.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0004047	biolink:NamedThing	aminomethyltransferase activity	Catalysis of the reaction: (6S)-tetrahydrofolate + S-aminomethyldihydrolipoylprotein = (6R)-5,10-methylenetetrahydrofolate + NH3 + dihydrolipoylprotein.	tmpzr1t_l9r_go_relaxed.owl	T-protein|tetrahydrofolate aminomethyltransferase activity|glycine-cleavage system T-protein activity|S-aminomethyldihydrolipoylprotein:(6S)-tetrahydrofolate aminomethyltransferase (ammonia-forming) activity|protein-S8-aminomethyldihydrolipoyllysine:tetrahydrofolate aminomethyltransferase (ammonia-forming) activity|protein-8-S-aminomethyldihydrolipoyllysine:tetrahydrofolate aminomethyltransferase (ammonia-forming) activity|glycine synthase activity				Reactome:R-HSA-5693977|RHEA:16945|MetaCyc:GCVT-RXN|EC:2.1.2.10									molecular_function											owl:Class	
GO:0008763	biolink:NamedThing	UDP-N-acetylmuramate-L-alanine ligase activity	Catalysis of the reaction: L-alanine + ATP + UDP-N-acetylmuramate = ADP + 2 H(+) + phosphate + UDP-N-acetylmuramoyl-L-alanine.	tmpzr1t_l9r_go_relaxed.owl	UDP-MurNAc:L-alanine ligase activity|UDPMurNAc-L-alanine synthetase activity|UDP-N-acetylmuramyl:L-alanine ligase activity|UDP-N-acetylmuramate:L-alanine ligase (ADP-forming)|uridine-diphosphate-N-acetylmuramate:L-alanine ligase activity|uridine diphosphate N-acetylmuramate:L-alanine ligase activity|uridine diphospho-N-acetylmuramoylalanine synthetase activity|UDP-acetylmuramyl-L-alanine synthetase activity|UDP-N-acetylmuramoylalanine synthetase activity|UDP-N-acetylmuramoyl-L-alanine synthetase activity|L-Ala ligase activity|uridine 5'-diphosphate-N-acetylmuramyl-L-alanine synthetase activity|MurC synthetase activity|alanine-adding enzyme activity|L-alanine-adding enzyme activity				RHEA:23372|EC:6.3.2.8|MetaCyc:UDP-NACMUR-ALA-LIG-RXN|KEGG_REACTION:R03193									molecular_function											owl:Class	
GO:0033781	biolink:NamedThing	cholesterol 24-hydroxylase activity	Catalysis of the reaction: cholesterol + H(+) + NADPH + O(2) = (24S)-24-hydroxycholesterol + H(2)O + NADP(+).	tmpzr1t_l9r_go_relaxed.owl	cholesterol 24S-hydroxylase activity|cholesterol 24-monooxygenase activity|cytochrome P450 46A1|CYP46|CYP46A1|cholesterol,NADPH:oxygen oxidoreductase (24-hydroxylating) activity				KEGG_REACTION:R07207|Reactome:R-HSA-192061|RHEA:22716|EC:1.14.14.25|MetaCyc:1.14.13.98-RXN									molecular_function											owl:Class	
GO:0008127	biolink:NamedThing	quercetin 2,3-dioxygenase activity	Catalysis of the reaction: H(+) + O(2) + quercetin = 2-(3,4-dihydroxybenzoyloxy)-4,6-dihydroxybenzoate + CO.	tmpzr1t_l9r_go_relaxed.owl	quercetin:oxygen 2,3-oxidoreductase (decyclizing)|flavonol 2,4-oxygenase activity|quercetinase activity				Reactome:R-HSA-8953398|RHEA:15381|EC:1.13.11.24|KEGG_REACTION:R02156|MetaCyc:QUERCETIN-23-DIOXYGENASE-RXN|UM-BBD_reactionID:r0891									molecular_function											owl:Class	
GO:0043765	biolink:NamedThing	T/G mismatch-specific endonuclease activity	Catalysis of the repair of T/G mismatches arising from deamination of 5-methylcytosine in DNA by nicking double-stranded DNA within the sequence CT(AT)GN or NT(AT)GG next to the mismatched thymidine residue. The incision is mismatch-dependent and strand-specific, in favor of the G-containing strand. The incision serves as a starting point for subsequent excision repair by DNA polymerase I, which excises thymidine and reinserts cytidine.	tmpzr1t_l9r_go_relaxed.owl	Vsr mismatch endonuclease|V.EcoKDcm|DNA mismatch endonuclease|very short patch repair protein													molecular_function											owl:Class	
GO:0099006	biolink:NamedThing	viral entry via permeabilization of endosomal membrane	The entry of a non-enveloped virus into a host eukaryotic cell, following endocytosis, via permeabilization of the endosomal membrane by membrane penetration protein(s) associated with the viral capsid.  In some cases, viral membrane-penetration protein require first to be activated to display its membrane penetrating activity. Activation can be due to receptor binding or the acidic pH of the endosomal lumen.	tmpzr1t_l9r_go_relaxed.owl	viral penetration via permeabilization of host membrane				VZ:985									biological_process											owl:Class	
GO:0021902	biolink:NamedThing	commitment of neuronal cell to specific neuron type in forebrain	The commitment of neuronal precursor cells to become specialized types of neurons in the forebrain.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0098601	biolink:NamedThing	selenomethionine adenosyltransferase activity	Catalysis of the reaction: ATP + L-Selenomethionine + H2O => Orthophosphate + Diphosphate + Se-Adenosylselenomethionine.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-2408551|RHEA:31211			dos	2014-04-15T15:15:03Z					molecular_function											owl:Class	
GO:0048761	biolink:NamedThing	collenchyma cell differentiation	The process in which a relatively unspecialized cell acquires specialized features of a collenchyma cell. This is a plant cell in which the primary cell walls are unevenly thickened, with most thickening occurring at the cell corners. Cells are living and able to grow, they are elongated, and lignin and secondary walls absent. Collenchyma cells make up collenchyma tissue which acts as a supporting tissue in growing shoots, leaves and petioles. This tissue is often arranged in cortical ribs, as seen prominently in celery and rhubarb petioles.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0050277	biolink:NamedThing	sedoheptulokinase activity	Catalysis of the reaction: ATP + sedoheptulose = ADP + 2 H(+) + sedoheptulose 7-phosphate.	tmpzr1t_l9r_go_relaxed.owl	ATP:sedoheptulose 7-phosphotransferase activity|heptulokinase activity|sedoheptulokinase (phosphorylating)				Reactome:R-HSA-8959719|KEGG_REACTION:R01844|MetaCyc:SEDOHEPTULOKINASE-RXN|EC:2.7.1.14|RHEA:23844									molecular_function											owl:Class	
GO:0070282	biolink:NamedThing	pyridoxine binding	Binding to pyridoxine, 4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol, a form of vitamin B6.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0034813	biolink:NamedThing	benzo(a)pyrene 7,8-dioxygenase activity	Catalysis of the reaction: benzo(a)pyrene + O2 = benzo(a)pyrene-cis-7,8-dihydrodiol.	tmpzr1t_l9r_go_relaxed.owl					EC:1.13.11.-|UM-BBD_reactionID:r1137									molecular_function											owl:Class	
GO:0140074	biolink:NamedThing	cardiac endothelial to mesenchymal transition	A transition where a cardiac endothelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell. Endocardial cells (specialized endothelial cells that line the heart) undergo EndMT, and give rise to mesenchymal cells necessary for proper heart development. EndMT, specifically generates valve progenitor cells that give rise to the mitral and tricuspid valves. EndMT also contributes to endocardial cushion formation, as well as to generation of cardiac fibroblasts and smooth muscle cells, but not cardiac myocytes.	tmpzr1t_l9r_go_relaxed.owl	EndMT|EndoMT							pg	2017-07-21T09:39:49Z					biological_process											owl:Class	
GO:0004792	biolink:NamedThing	thiosulfate sulfurtransferase activity	Catalysis of the reaction: hydrogen cyanide + thiosulfate = H(+) + sulfite + thiocyanate.	tmpzr1t_l9r_go_relaxed.owl	rhodanase activity|thiosulphate sulphurtransferase activity|thiosulfate cyanide transsulfurase activity|rhodanese activity|thiosulfate:cyanide sulfurtransferase activity|thiosulfate thiotransferase activity				RHEA:16881|KEGG_REACTION:R01931|EC:2.8.1.1|MetaCyc:THIOSULFATE-SULFURTRANSFERASE-RXN|Reactome:R-HSA-9013198									molecular_function											owl:Class	
GO:0048720	biolink:NamedThing	posterior cibarial plate morphogenesis	The process in which the anatomical structures of the posterior cibarial plate are generated and organized.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0070934	biolink:NamedThing	CRD-mediated mRNA stabilization	An mRNA stabilization process in which one or more RNA-binding proteins associate with a sequence in the open reading frame called the coding region instability determinant (CRD).	tmpzr1t_l9r_go_relaxed.owl	coding region determinant-mediated mRNA stabilization							mah	2009-09-21T02:57:06Z					biological_process											owl:Class	
GO:0001896	biolink:NamedThing	autolysis	A programmed cell death process observed in bacteria and filamentous fungi and leading to spontaneous death by lysis. Examples are lysis of the mother cell during sporulation of Bacillus subtilis and self-degradation of fungal cells in Aspergillus nidulans. Autolysis is also involved in bacterial biofilm formation.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Autolysis									biological_process											owl:Class	
GO:0098617	biolink:NamedThing	adenylylselenate kinase activity	Catalysis of the reaction: ATP + adenylylselenate => ADP + 3'-phosphoadenylylselenate.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-2408540									molecular_function											owl:Class	
GO:0009836	biolink:NamedThing	fruit ripening, climacteric	A fruit ripening process that involves a burst of respiration and ethylene (ethene) evolution at the onset.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0045238	biolink:NamedThing	CXCR2 chemokine receptor binding	Binding to a CXCR2 chemokine receptor.	tmpzr1t_l9r_go_relaxed.owl	CXCR2 chemokine receptor ligand													molecular_function											owl:Class	
GO:0000413	biolink:NamedThing	protein peptidyl-prolyl isomerization	The modification of a protein by cis-trans isomerization of a proline residue.	tmpzr1t_l9r_go_relaxed.owl	protein proline isomerization													biological_process											owl:Class	
GO:0016871	biolink:NamedThing	cycloartenol synthase activity	Catalysis of the reaction: (S)-2,3-epoxysqualene = cycloartenol.	tmpzr1t_l9r_go_relaxed.owl	2,3-oxidosqualene-cycloartenol cyclase activity|(S)-2,3-epoxysqualene mutase (cyclizing, cycloartenol-forming)|2,3-epoxysqualene cycloartenol-cyclase activity|2,3-epoxysqualene--cycloartenol cyclase activity|oxidosqualene:cycloartenol cyclase activity|squalene-2,3-epoxide-cycloartenol cyclase activity				MetaCyc:CYCLOARTENOL-SYNTHASE-RXN|KEGG_REACTION:R03200|EC:5.4.99.8|RHEA:21308									molecular_function											owl:Class	
GO:0034474	biolink:NamedThing	U2 snRNA 3'-end processing	Any process involved in forming the mature 3' end of a U2 snRNA molecule.	tmpzr1t_l9r_go_relaxed.owl	U2 snRNA 3' end processing													biological_process											owl:Class	
GO:0016275	biolink:NamedThing	[cytochrome c]-arginine N-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + (cytochrome c)-arginine = S-adenosyl-L-homocysteine + (cytochrome c)-N(omega)-methyl-arginine.	tmpzr1t_l9r_go_relaxed.owl	cytochrome c-arginine N-methyltransferase activity|S-adenosyl-L-methionine:cytochrome c-arginine nomega-methyltransferasea|S-adenosyl-L-methionine:cytochrome c-arginine omega-N-methyltransferasea				RHEA:21872|EC:2.1.1.124|MetaCyc:2.1.1.124-RXN									molecular_function											owl:Class	
GO:0097718	biolink:NamedThing	disordered domain specific binding	Binding to a disordered domain of a protein.	tmpzr1t_l9r_go_relaxed.owl	disordered protein domain specific binding							pr	2016-08-23T16:42:51Z					molecular_function											owl:Class	
GO:0032143	biolink:NamedThing	single thymine insertion binding	Binding to a double-stranded DNA region containing a single thymine insertion or a deletion that results in an unpaired thymine.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0090008	biolink:NamedThing	hypoblast development	The process whose specific outcome is the progression of the hypoblast over time, from its formation to the mature structure. The hypoblast is a tissue formed from the inner cell mass that lies beneath the epiblast.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-07-29T10:25:54Z					biological_process											owl:Class	
GO:1901370	biolink:NamedThing	response to glutathione	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glutathione stimulus.	tmpzr1t_l9r_go_relaxed.owl								mah	2012-09-21T13:59:24Z					biological_process											owl:Class	
GO:0048060	biolink:NamedThing	negative gravitaxis	The directed movement of a motile cell or organism away from the source of gravity.	tmpzr1t_l9r_go_relaxed.owl	negative gravitactic behavior|negative taxis in response to gravitytaxis in response to gravitational stimulus|negative geotactic behavior|negative geotactic behaviour|negative taxis in response to gravity|negative gravitactic behaviour											GO:0048063		biological_process											owl:Class	
GO:0021645	biolink:NamedThing	vagus nerve structural organization	The process that contributes to the act of creating the structural organization of the vagus nerve. This process pertains to the physical shaping of a rudimentary structure. This nerve is primarily sensory but also has visceromotor components. It originates in the brain stem and controls many autonomic functions of the heart, lungs, stomach, pharynx, larynx, trachea, esophagus and other gastrointestinal tract components. It controls some motor functions such as speech. The sensory branches mediate sensation from the pharynx, larynx, thorax and abdomen; it also innervates taste buds in the epiglottis.	tmpzr1t_l9r_go_relaxed.owl	CN X structural organization|vagus nerve structural organisation													biological_process											owl:Class	
GO:0047782	biolink:NamedThing	coniferin beta-glucosidase activity	Catalysis of the reaction: H2O + coniferin = D-glucose + coniferol.	tmpzr1t_l9r_go_relaxed.owl	coniferin b-glucosidase activity|coniferin-hydrolyzing beta-glucosidase activity|coniferin beta-D-glucosidase activity				EC:3.2.1.126|MetaCyc:CONIFERIN-BETA-GLUCOSIDASE-RXN|RHEA:12252									molecular_function											owl:Class	
GO:0016784	biolink:NamedThing	3-mercaptopyruvate sulfurtransferase activity	Catalysis of the reaction: 3-mercaptopyruvate + cyanide = pyruvate + thiocyanate.	tmpzr1t_l9r_go_relaxed.owl	3-mercaptopyruvate:cyanide sulfurtransferase activity|3-mercaptopyruvate sulphurtransferase activity|beta-mercaptopyruvate sulfurtransferase activity|mercaptopyruvate sulfurtransferase activity				Reactome:R-HSA-9034756|Reactome:R-HSA-9013533|EC:2.8.1.2|Reactome:R-HSA-9013471|RHEA:21740|Reactome:R-HSA-9012721|MetaCyc:MERCAPYSTRANS-RXN									molecular_function											owl:Class	
GO:0047311	biolink:NamedThing	1D-1-guanidino-3-amino-1,3-dideoxy-scyllo-inositol transaminase activity	Catalysis of the reaction: 1D-1-guanidino-3-amino-1,3-dideoxy-scyllo-inositol + pyruvate = 1D-1-guanidino-1-deoxy-3-dehydro-scyllo-inositol + L-alanine.	tmpzr1t_l9r_go_relaxed.owl	1D-1-guanidino-3-amino-1,3-dideoxy-scyllo-inositol:pyruvate aminotransferase activity|1D-1-guanidino-3-amino-1,3-dideoxy-scyllo-inositol aminotransferase activity|L-alanine-N-amidino-3-(or 5-)keto-scyllo-inosamine transaminase activity|guanidinoaminodideoxy-scyllo-inositol-pyruvate aminotransferase activity				KEGG_REACTION:R03502|MetaCyc:2.6.1.56-RXN|EC:2.6.1.56|RHEA:15497									molecular_function											owl:Class	
GO:0102979	biolink:NamedThing	homofuraneol oxidoreductase activity	Catalysis of the reaction: homofuraneol + NADP <=> (2E)-2-ethylidene-4-hydroxy-5-methyl-3(2H)-furanone + NADPH + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-9564|RHEA:53944									molecular_function											owl:Class	
GO:0060305	biolink:NamedThing	regulation of cell diameter	Any process that modulates the diameter of a cell, the length of a line segment that crosses through the center of a circular section through a cell.	tmpzr1t_l9r_go_relaxed.owl	regulation of cell width													biological_process											owl:Class	
GO:1901025	biolink:NamedThing	ripoptosome assembly involved in extrinsic apoptotic signaling pathway	The aggregation, arrangement and bonding together of ripoptosome components leading to apoptosis via the extrinsic apoptotic signaling pathway.	tmpzr1t_l9r_go_relaxed.owl								pr	2012-06-19T08:49:33Z					biological_process											owl:Class	
GO:0042163	biolink:NamedThing	interleukin-12 beta subunit binding	Binding to the beta subunit of interleukin-12.	tmpzr1t_l9r_go_relaxed.owl	NKSFp40 binding|CLMFp40 binding|IL-12p40 binding|IL-12B binding													molecular_function											owl:Class	
GO:0004013	biolink:NamedThing	adenosylhomocysteinase activity	Catalysis of the reaction: S-adenosyl-L-homocysteine + H2O = adenosine + L-homocysteine.	tmpzr1t_l9r_go_relaxed.owl	S-adenosylhomocysteinase activity|S-adenosylhomocysteine hydrolase activity|S-adenosyl-L-homocysteine hydrolase activity|SAHase activity|AdoHcyase activity|adenosylhomocysteine hydrolase activity|S-adenosylhomocysteine synthase activity				RHEA:21708|EC:3.3.1.1|Reactome:R-HSA-5579084|MetaCyc:ADENOSYLHOMOCYSTEINASE-RXN|Reactome:R-HSA-174401									molecular_function											owl:Class	
GO:0039704	biolink:NamedThing	viral translational shunt	A viral translation initiation mechanism where ribosomes are loaded onto viral mRNA at the 5'-cap structure and start scanning for a short distance before by-passing the large internal leader region and initiating at a downstream start site.	tmpzr1t_l9r_go_relaxed.owl	ribosomal shunt initiation pathway				VZ:608	This term is intended to annotate gene products involved in the process of viral translational shunt, not viral proteins produced by this translation process.		bf	2013-11-21T17:08:40Z					biological_process											owl:Class	
GO:0031802	biolink:NamedThing	type 5 metabotropic glutamate receptor binding	Binding to a type 5 metabotropic glutamate receptor.	tmpzr1t_l9r_go_relaxed.owl	type 5 metabotropic glutamate receptor ligand													molecular_function											owl:Class	
GO:0102663	biolink:NamedThing	gibberellin A34,2-oxoglutarate:oxygen oxidoreductase activity	Catalysis of the reaction: gibberellin A34 + 2-oxoglutarate + O2 <=> H+ + gibberellin A34-catabolite + succinate + carbon dioxide + H2O.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-292									molecular_function											owl:Class	
GO:1901930	biolink:NamedThing	alpha-copaene catabolic process	The chemical reactions and pathways resulting in the breakdown of alpha-copaene.	tmpzr1t_l9r_go_relaxed.owl	alpha-copaene degradation|alpha-copaene breakdown|alpha-copaene catabolism							ms	2013-02-18T14:54:43Z					biological_process											owl:Class	
GO:0015254	biolink:NamedThing	glycerol channel activity	Enables the facilitated diffusion of glycerol (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-432049|Reactome:R-HSA-507869|Reactome:R-HSA-432074|Reactome:R-HSA-507871|RHEA:29675									molecular_function											owl:Class	
GO:0102251	biolink:NamedThing	all-trans-beta-apo-10'-carotenal cleavage oxygenase activity	Catalysis of the reaction: 10'-apo-beta-carotenal + O2 <=> 13-apo-beta-carotenone + 4-methylocta-2,4,6-trienedial.	tmpzr1t_l9r_go_relaxed.owl					RHEA:26401|EC:1.13.11.70|MetaCyc:RXN-12393									molecular_function											owl:Class	
GO:0038060	biolink:NamedThing	nitric oxide-cGMP-mediated signaling pathway	Any intracellular signal transduction in which the signal is passed on within the cell by nitric oxide (NO) activating soluble guanylyl cyclase (sGC). Includes synthesis of nitric oxide, guanylyl cyclase activity, and downstream effectors that further transmit the signal within the cell following activation by cGMP.	tmpzr1t_l9r_go_relaxed.owl	canonical nitric oxide signaling|classical nitric oxide signaling|nitric oxide-cGMP-mediated signalling pathway|NO-cGMP signaling pathway							bf	2012-01-10T05:32:39Z					biological_process											owl:Class	
GO:0072518	biolink:NamedThing	Rho-dependent protein serine/threonine kinase activity	Rho GTPase-dependent catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein.	tmpzr1t_l9r_go_relaxed.owl	ROCK kinase activity|Rho-associated protein kinase activity					This reaction requires binding of the GTPase Rho.		mah	2010-12-22T11:07:29Z					molecular_function											owl:Class	
GO:0002167	biolink:NamedThing	VRK3/VHR/ERK complex	A ternary complex consisting of VRK3, VHR (Dusp3), and ERK1 (Mapk3) existing in neuronal cells, and is involved in regulation of the ERK signaling pathway.	tmpzr1t_l9r_go_relaxed.owl								hjd	2010-03-04T01:15:05Z					cellular_component											owl:Class	
GO:0047816	biolink:NamedThing	D-arabinose 1-dehydrogenase (NAD+) activity	Catalysis of the reaction: D-arabinose + NAD+ = D-arabinono-1,4-lactone + NADH.	tmpzr1t_l9r_go_relaxed.owl	D-arabinose:NAD+ 1-oxidoreductase activity|NAD-pentose-dehydrogenase activity|arabinose(fucose)dehydrogenase activity				RHEA:20457|EC:1.1.1.116|MetaCyc:D-ARABINOSE-1-DEHYDROGENASE-RXN									molecular_function											owl:Class	
GO:0110094	biolink:NamedThing	polyphosphate-mediated signaling	Any process that mediates the transfer of information from one cell to another using polyphosphate as the signal.	tmpzr1t_l9r_go_relaxed.owl	polyphosphate signaling							kmv	2018-02-15T16:42:30Z					biological_process											owl:Class	
GO:0010275	biolink:NamedThing	NAD(P)H dehydrogenase complex assembly	The aggregation, arrangement and bonding together of a set of components to form NAD(P)H dehydrogenase complex, which is involved in electron transport from an unidentified electron donor, possibly NAD(P)H or ferredoxin(Fd) to the plastoquinone pool.	tmpzr1t_l9r_go_relaxed.owl	NAD(P)H dehydrogenase complex (plastoquinone) assembly													biological_process											owl:Class	
GO:1904401	biolink:NamedThing	cellular response to Thyroid stimulating hormone	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a Thyroid stimulating hormone stimulus.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-06-23T20:57:59Z					biological_process											owl:Class	
GO:0071082	biolink:NamedThing	alpha9-beta1 integrin-tenascin complex	A protein complex that consists of an alpha9-beta1 integrin complex bound to the extracellular matrix protein tenascin.	tmpzr1t_l9r_go_relaxed.owl	ITGA9-ITGB1-TNC complex							mah	2009-11-06T04:43:58Z					cellular_component											owl:Class	
GO:0021787	biolink:NamedThing	chemorepulsion of branchiomotor neuron axon in neural tube	The process in which a branchiomotor neuron growth cone in the neural tube is directed to a specific target site in the neural tube in response to a repulsive chemical cue. Branchiomotor neurons are located in the hindbrain and innervate branchial arch-derived muscles that control jaw movements, facial expression, the larynx, and the pharynx.	tmpzr1t_l9r_go_relaxed.owl	negative chemotaxis of branchiomotor neuron axon in neural tube													biological_process											owl:Class	
GO:0016630	biolink:NamedThing	protochlorophyllide reductase activity	Catalysis of the reaction: chlorophyllide a + NADP+ = protochlorophyllide + NADPH + H+.	tmpzr1t_l9r_go_relaxed.owl	NADPH-protochlorophyllide reductase activity|protochlorophyllide oxidoreductase activity|chlorophyllide-a:NADP+ 7,8-oxidoreductase activity|NADPH2-protochlorophyllide oxidoreductase activity|NADPH-protochlorophyllide oxidoreductase activity|protochlorophyllide photooxidoreductase activity				MetaCyc:RXN1F-10|RHEA:11132|EC:1.3.1.33									molecular_function											owl:Class	
GO:0031870	biolink:NamedThing	thromboxane A2 receptor binding	Binding to a thromboxane A2 receptor.	tmpzr1t_l9r_go_relaxed.owl	prostanoid TP receptor binding|thromboxane A2 receptor ligand													molecular_function											owl:Class	
GO:0050589	biolink:NamedThing	leucocyanidin oxygenase activity	Catalysis of the reaction: leucocyanidin + 2-oxoglutarate + O2 = cis- or trans-dihydroquercetin + succinate + CO2 + 2 H2O.	tmpzr1t_l9r_go_relaxed.owl	leucoanthocyanidin hydroxylase|leucoanthocyanidin dioxygenase activity|leucocyanidin,2-oxoglutarate:oxygen oxidoreductase activity|anthocyanidin synthase activity				MetaCyc:RXN-602|EC:1.14.20.4							GO:0045432		molecular_function											owl:Class	
GO:0102892	biolink:NamedThing	betanidin 5-O-glucosyltransferase activity	Catalysis of the reaction: UDP-alpha-D-glucose + betanidin <=> H+ + betanin + UDP.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-8479									molecular_function											owl:Class	
GO:0075325	biolink:NamedThing	spore dispersal	Any process in which an organism disseminates its spores.	tmpzr1t_l9r_go_relaxed.owl	spore dispersal on or near host during symbiotic interaction|passive spore dispersal on or near host|active spore dispersal on or near host|active spore dispersal on or near host during symbiotic interaction|spore dispersal on or near host	https://github.com/geneontology/go-ontology/issues/18823										GO:0075327|GO:0075326		biological_process											owl:Class	
GO:0052656	biolink:NamedThing	L-isoleucine transaminase activity	Catalysis of the reaction: 2-oxoglutarate + L-isoleucine = (S)-3-methyl-2-oxopentanoic acid + L-glutamic acid.	tmpzr1t_l9r_go_relaxed.owl	L-isoleucine aminotransferase activity				MetaCyc:BRANCHED-CHAINAMINOTRANSFERILEU-RXN|RHEA:24801|KEGG_REACTION:R02199|EC:2.6.1.42									molecular_function											owl:Class	
GO:0086040	biolink:NamedThing	sodium:proton antiporter activity involved in regulation of cardiac muscle cell membrane potential	Enables the transfer of a solute or solutes from one side of a cardiac muscle cell membrane to the other according to the reaction: Na+(out) + H+(in) = Na+(in) + H+(out). This transfer contributes to the regulation of the cardiac muscle cell plasma membrane potential.	tmpzr1t_l9r_go_relaxed.owl	sodium:hydrogen antiporter activity involved in regulation of cardiac muscle cell membrane potential							tb	2011-11-11T03:33:44Z					molecular_function											owl:Class	
GO:0004514	biolink:NamedThing	nicotinate-nucleotide diphosphorylase (carboxylating) activity	Catalysis of the reaction: CO(2) + diphosphate + nicotinate D-ribonucleotide = 5-phospho-alpha-D-ribose 1-diphosphate + 2 H(+) + quinolinate.	tmpzr1t_l9r_go_relaxed.owl	quinolinate phosphoribosyltransferase (decarboxylating) activity|quinolinic acid phosphoribosyltransferase activity|NAD pyrophosphorylase activity|QAPRTase activity|nicotinate mononucleotide pyrophosphorylase (carboxylating)|quinolinic phosphoribosyltransferase activity|nicotinate-nucleotide pyrophosphorylase (carboxylating) activity|nicotinate-nucleotide:diphosphate phospho-alpha-D-ribosyltransferase (carboxylating)				EC:2.4.2.19|RHEA:12733|Reactome:R-HSA-197268|MetaCyc:QUINOPRIBOTRANS-RXN|KEGG_REACTION:R03348									molecular_function											owl:Class	
GO:0102929	biolink:NamedThing	lachrymatory factor synthase activity	Catalysis of the reaction: 1-propenylsulfenate = propanethiol S-oxide.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-8911									molecular_function											owl:Class	
GO:0042037	biolink:NamedThing	peptidyl-histidine methylation, to form pros-methylhistidine	The methylation of peptidyl-L-histidine to form peptidyl-L-3'-methyl-L-histidine (otherwise known as pi-methylhistidine, pros-methylhistidine).	tmpzr1t_l9r_go_relaxed.owl	peptidyl-histidine pros-methylation				RESID:AA0073							GO:0042260		biological_process											owl:Class	
GO:0106410	biolink:NamedThing	box C/D RNA 5'-end processing	Any process involved in forming the mature 5' end of a box C/D RNA molecule.	tmpzr1t_l9r_go_relaxed.owl								hjd	2021-11-02 14:11:42+00:00					biological_process											owl:Class	
GO:0050347	biolink:NamedThing	trans-octaprenyltranstransferase activity	Catalysis of the reaction: all-trans-octaprenyl diphosphate + isopentenyl diphosphate = all-trans-nonaprenyl diphosphate + diphosphate.	tmpzr1t_l9r_go_relaxed.owl	all-trans-nonaprenyl-diphosphate synthase activity|(E)-octaprenyl-diphosphate:isopentenyl-diphosphate octaprenyltranstransferase activity|solanesyl pyrophosphate synthetase activity|nonaprenyl pyrophosphate synthetase activity|terpenoidallyltransferase activity|solanesyl-diphosphate synthase activity|polyprenylpyrophosphate synthetase activity|terpenyl pyrophosphate synthetase activity|SPP synthase activity|trans-prenyltransferase activity				KEGG_REACTION:R07267|RHEA:11324									molecular_function											owl:Class	
GO:1901102	biolink:NamedThing	gramicidin S catabolic process	The chemical reactions and pathways resulting in the breakdown of gramicidin S.	tmpzr1t_l9r_go_relaxed.owl	gramicidin S breakdown|gramicidin S catabolism|gramicidin S degradation							yaf	2012-07-11T02:30:52Z					biological_process											owl:Class	
GO:1990086	biolink:NamedThing	lens fiber cell apoptotic process	Any apoptotic process in a lens fiber cell. Lens fiber cells are elongated, tightly packed cells that make up the bulk of the mature lens in a camera-type eye.	tmpzr1t_l9r_go_relaxed.owl								hjd	2013-05-01T19:09:28Z					biological_process											owl:Class	
GO:0090728	biolink:NamedThing	negative regulation of brood size	Any process that decreases brood size. Brood size is the number of progeny that survive embryogenesis and are cared for at one time.	tmpzr1t_l9r_go_relaxed.owl								tb	2016-12-19T15:07:32Z					biological_process											owl:Class	
GO:0050199	biolink:NamedThing	piperidine N-piperoyltransferase activity	Catalysis of the reaction: (E,E)-piperoyl-CoA + piperidine = N-[(E,E)-piperoyl]piperidine + CoA + H(+).	tmpzr1t_l9r_go_relaxed.owl	piperidine piperoyltransferase activity|piperoyl-CoA:piperidine N-piperoyltransferase activity|(E,E)-piperoyl-CoA:piperidine N-piperoyltransferase activity				EC:2.3.1.145|RHEA:14561|KEGG_REACTION:R03994|MetaCyc:PIPERIDINE-N-PIPEROYLTRANSFERASE-RXN									molecular_function											owl:Class	
GO:0098031	biolink:NamedThing	icosahedral viral capsid, collar	A small disk located at the base of some icosahedral virus capsids.	tmpzr1t_l9r_go_relaxed.owl								bm	2012-07-19T15:01:12Z					cellular_component											owl:Class	
GO:0050101	biolink:NamedThing	mimosinase activity	Catalysis of the reaction: L-mimosine + H(2)O = 3-hydroxy-4H-pyrid-4-one + L-serine.	tmpzr1t_l9r_go_relaxed.owl	mimosine amidohydrolase activity				RHEA:13373|MetaCyc:MIMOSINASE-RXN|KEGG_REACTION:R04350|EC:3.5.1.61									molecular_function											owl:Class	
GO:0047469	biolink:NamedThing	4-carboxymethyl-4-methylbutenolide mutase activity	Catalysis of the reaction: 4-carboxymethyl-4-methylbut-2-en-1,4-olide = 4-carboxymethyl-3-methylbut-2-en-1,4-olide.	tmpzr1t_l9r_go_relaxed.owl	4-methyl-3-enelactone methyl isomerase activity|4-methyl-2-enelactone isomerase activity|4-carboxymethyl-4-methylbut-2-en-1,4-olide methylmutase activity|4-methylmuconolactone methylisomerase activity|4-methyl-2-enelactone methyl-isomerase activity				MetaCyc:5.4.99.14-RXN|KEGG_REACTION:R04510|RHEA:19237|EC:5.4.99.14									molecular_function											owl:Class	
GO:0048571	biolink:NamedThing	long-day photoperiodism	Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a day length that exceeds a particular duration known as the 'critical day length'. The critical day length varies between species. Although the term long-day is used, most species actually respond to the duration of the night, so that the response will occur when a period of darkness falls short of the number of hours defined by 24 hours minus the critical day length.	tmpzr1t_l9r_go_relaxed.owl	response to long-day|response to long-day photoperiod|short-night photoperiodism|response to short-night													biological_process											owl:Class	
GO:0052613	biolink:NamedThing	canthaxanthin 3-hydroxylase activity	Catalysis of the reaction: canthaxanthin + a reduced electron acceptor + oxygen = adonirubin + an oxidized electron acceptor + H2O.	tmpzr1t_l9r_go_relaxed.owl	carotene beta-ring hydroxylase activity|beta-ring carotenoid 3-hydroxylase activity|beta-carotene hydroxylase activity				MetaCyc:RXN-8186									molecular_function											owl:Class	
GO:0004141	biolink:NamedThing	dethiobiotin synthase activity	Catalysis of the reaction: 7,8-diaminononanoate + ATP + CO(2) = ADP + dethiobiotin + 4 H(+) + phosphate.	tmpzr1t_l9r_go_relaxed.owl	desthiobiotin synthase activity|DTB synthetase activity|7,8-diaminononanoate:carbon-dioxide cyclo-ligase (ADP-forming)				RHEA:15805|MetaCyc:DETHIOBIOTIN-SYN-RXN|KEGG_REACTION:R03182|EC:6.3.3.3									molecular_function											owl:Class	
GO:0062065	biolink:NamedThing	box H/ACA snoRNP complex binding	Binding to a box H/ACA snoRNP complex.	tmpzr1t_l9r_go_relaxed.owl								dph	2018-08-31T14:03:43Z					molecular_function											owl:Class	
GO:0018733	biolink:NamedThing	3,4-dihydrocoumarin hydrolase activity	Catalysis of the reaction: 3,4-dihydrocoumarin + H2O = 3-(2-hydroxyphenyl) propionate.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0419|EC:3.1.1.35									molecular_function											owl:Class	
GO:0060250	biolink:NamedThing	germ-line stem-cell niche homeostasis	A homeostatic process involved in the maintenance of an internal steady state within the germ-line stem-cell niche. This includes control of cellular proliferation and death and control of metabolic function that allows the niche to continue to function. A gem-line stem-cell niche is an anatomical structure that regulates how germ-line stem-cells are used and saves them from depletion.	tmpzr1t_l9r_go_relaxed.owl	maintenance of germ-line stem cell niche|maintenance of germ line stem-cell niche|maintenance of germ-line stem-cell niche|maintenance of germ line stem cell niche|germ-line stem-cell niche maintenance													biological_process											owl:Class	
GO:0047750	biolink:NamedThing	cholestenol delta-isomerase activity	Catalysis of the reaction: 5-alpha-cholest-7-en-3-beta-ol = 5-alpha-cholest-8-en-3-beta-ol.	tmpzr1t_l9r_go_relaxed.owl	delta7-cholestenol delta7-delta8-isomerase activity|cholestenol D-isomerase activity				RHEA:15281|MetaCyc:RXN66-25|EC:5.3.3.5									molecular_function											owl:Class	
GO:0051921	biolink:NamedThing	adenosylcobyric acid synthase (glutamine-hydrolyzing) activity	Catalysis of the reaction: 4 L-glutamine + adenosylcob(III)yrinate a,c-diamide + 4 ATP + 4 H(2)O = 4 L-glutamate + adenosylcobyrate + 4 ADP + 8 H(+) + 4 phosphate.	tmpzr1t_l9r_go_relaxed.owl	Ado-cobyric acid synthase [glutamine hydrolyzing] activity|CobQ activity|cobyric acid synthase activity|5'-deoxy-5'-adenosylcobyrinic-acid-a,c-diamide:L-glutamine amido-ligase activity|adenosylcobyric acid synthase (glutamine-hydrolysing) activity|adenosylcobyrinic-acid-a,c-diamide:L-glutamine amido-ligase (ADP-forming)				KEGG_REACTION:R05225|MetaCyc:R345-RXN|RHEA:23256|EC:6.3.5.10									molecular_function											owl:Class	
GO:0071933	biolink:NamedThing	Arp2/3 complex binding	Binding to an Arp2/3 complex, a protein complex that contains two actin-related proteins, Arp2 and Arp3, and five novel proteins (ARPC1-5).	tmpzr1t_l9r_go_relaxed.owl								mah	2010-09-29T02:48:41Z					molecular_function											owl:Class	
GO:0051959	biolink:NamedThing	dynein light intermediate chain binding	Binding to a light intermediate chain of the dynein complex.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0017060	biolink:NamedThing	3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity	Catalysis of the reaction: GDP-L-fucose + beta-D-galactosyl-(1,3)-N-acetyl-D-glucosaminyl-R = GDP + beta-D-galactosyl-(1,3)-[alpha-L-fucosyl-(1,4)]-N-acetyl-D-glucosaminyl-R.	tmpzr1t_l9r_go_relaxed.owl	(Le(a))-dependent (alpha-3/4)-fucosyltransferase activity|GDP-L-fucose:3-beta-D-galactosyl-N-acetyl-D-glucosaminyl-R 4I-alpha-L-fucosyltransferase activity|guanosine diphosphofucose-glycoprotein 4-alpha-fucosyltransferase activity|Lewis alpha-(1,3/4)-fucosyltransferase activity|Lewis alpha-(1->3/4)-fucosyltransferase activity|Lewis blood group alpha-(1,3/4)-fucosyltransferase activity|blood group Lewis alpha-4-fucosyltransferase activity|alpha-(1,3/1,4) fucosyltransferase III activity|Lewis(Le) blood group gene-dependent alpha-(1,3/4)-L-fucosyltransferase activity|guanosine diphosphofucose-beta-acetylglucosaminylsaccharide 4-alpha-L-fucosyltransferase activity|alpha-(1,4)-L-fucosyltransferase activity|3-alpha-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity|blood-group substance Le(a)-dependent fucosyltransferase activity|Lewis(Le) blood group gene-dependent alpha-(1->3/4)-L-fucosyltransferase activity|alpha-4-L-fucosyltransferase activity|galactoside 3(4)-L-fucosyltransferase activity|FucT-II activity|Lewis blood group alpha-(1->3/4)-fucosyltransferase activity|(Lea)-dependent (alpha-3/4)-fucosyltransferase activity|blood-group substance Lea-dependent fucosyltransferase|alpha-(1->4)-L-fucosyltransferase activity|fuca(1,3)-glycosidic linkage formation|guanosine diphosphofucose-glycoprotein 4-alpha-L-fucosyltransferase activity|GDP-beta-L-fucose:3-beta-D-galactosyl-N-acetyl-D-glucosaminyl-R 4I-alpha-L-fucosyltransferase activity|alpha(1,4)-L-fucosyltransferase activity|beta-acetylglucosaminylsaccharide fucosyltransferase activity|Lewis FT activity				Reactome:R-HSA-5693925|MetaCyc:2.4.1.65-RXN|Reactome:R-HSA-9603986|RHEA:23628|EC:2.4.1.65									molecular_function											owl:Class	
GO:0031861	biolink:NamedThing	prolactin-releasing peptide receptor binding	Binding to a prolactin-releasing peptide receptor.	tmpzr1t_l9r_go_relaxed.owl	prolactin-releasing peptide receptor ligand													molecular_function											owl:Class	
GO:0018859	biolink:NamedThing	4-hydroxybenzoate-CoA ligase activity	Catalysis of the reaction: ATP + 4-hydroxybenzoate + CoA = AMP + diphosphate + 4-hydroxybenzoyl-CoA.	tmpzr1t_l9r_go_relaxed.owl	4-hydroxybenzoate-CoA synthetase activity|4-hydroxybenzoyl coenzyme A synthetase activity|4-hydroxybenzoyl-CoA ligase activity|4-hydroxybenzoate:CoA ligase (AMP-forming)|4-hydroxybenzoate-coenzyme A ligase (AMP-forming)				EC:6.2.1.27|RHEA:23116|UM-BBD_reactionID:r0156|KEGG_REACTION:R01300|MetaCyc:4-HYDROXYBENZOATE--COA-LIGASE-RXN									molecular_function											owl:Class	
GO:0004160	biolink:NamedThing	dihydroxy-acid dehydratase activity	Catalysis of the reaction: 2,3-dihydroxy-3-methylbutanoate = 3-methyl-2-oxobutanoate + H2O.	tmpzr1t_l9r_go_relaxed.owl	alpha,beta-dihydroxyisovalerate dehydratase activity|2,3-dihydroxyisovalerate dehydratase activity|2,3-dihydroxy-acid hydro-lyase (3-methyl-2-oxobutanoate-forming)|alpha,beta-dihydroxyacid dehydratase activity|DHAD|2,3-dihydroxy-acid hydro-lyase activity|acetohydroxyacid dehydratase activity|dihydroxy acid dehydrase activity				MetaCyc:DIHYDROXYISOVALDEHYDRAT-RXN|RHEA:20936|EC:4.2.1.9									molecular_function											owl:Class	
GO:0048211	biolink:NamedThing	Golgi vesicle docking	The initial attachment of a Golgi transport vesicle membrane to a target membrane, mediated by proteins protruding from the membrane of the Golgi vesicle and the target membrane.	tmpzr1t_l9r_go_relaxed.owl	Golgi-derived vesicle docking|dictyosome vesicle docking to target membrane|Golgi vesicle docking with target membrane|Golgi vesicle to membrane docking													biological_process											owl:Class	
GO:1990070	biolink:NamedThing	TRAPPI protein complex	A complex that tethers COPII vesicles at ER-Golgi intermediate compartment. Its role in this part of the vesicular transport may start at the ER exit sites. Binds to a component of the COPII coat. In yeast it includes the following subunits: Bet3 (as homodimer), Bet5, Trs20, Trs23, Trs31, Trs33 which are regarded as the core subunits of all TRAPP complexes in yeast.	tmpzr1t_l9r_go_relaxed.owl	TRAPP core complex							bhm	2013-03-28T14:04:40Z					cellular_component											owl:Class	
GO:0090126	biolink:NamedThing	protein-containing complex assembly involved in synapse maturation	The aggregation, arrangement and bonding together of a set of components to form a protein complex that contributes to synapse maturation.	tmpzr1t_l9r_go_relaxed.owl	protein complex assembly involved in synapse maturation							tb	2009-12-07T02:49:28Z					biological_process											owl:Class	
GO:0030423	biolink:NamedThing	targeting of mRNA for destruction involved in RNA interference	The process in which small interfering RNAs target cognate mRNA molecules for degradation.	tmpzr1t_l9r_go_relaxed.owl	RNA interference, targeting of mRNA for destruction													biological_process											owl:Class	
GO:0043979	biolink:NamedThing	histone H2B-K5 acetylation	The modification of histone H2B by the addition of an acetyl group to a lysine residue at position 5 of the histone.	tmpzr1t_l9r_go_relaxed.owl	histone H2B acetylation at K5													biological_process											owl:Class	
GO:0032283	biolink:NamedThing	plastid acetate CoA-transferase complex	An acetate CoA-transferase complex located in the stroma of a plastid.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0016060	biolink:NamedThing	metarhodopsin inactivation	The process in which metarhodopsin is prevented from generating molecular signals. Activated rhodopsin (R*) is inactivated by a two-step process: first, R* is phosphorylated by rhodopsin kinase which lowers the activity of R*. Second, the protein arrestin binds to phosphorylated R* to de-activate it.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0004703	biolink:NamedThing	G protein-coupled receptor kinase activity	Catalysis of the reaction: ATP + G protein-coupled receptor = ADP + G protein-coupled receptor phosphate.	tmpzr1t_l9r_go_relaxed.owl	GPCR phosphorylating protein kinase activity|G protein coupled receptor phosphorylating protein kinase activity|GPCRK|G-protein coupled receptor kinase activity|GPCR kinase activity|GRK5|ATP:G-protein-coupled receptor phosphotransferase activity|G-protein-coupled receptor phosphorylating protein kinase activity|STK16|GRK6|GRK4				EC:2.7.11.16|RHEA:12008							GO:0004678		molecular_function											owl:Class	
GO:0031680	biolink:NamedThing	G-protein beta/gamma-subunit complex	The heterodimer formed by the beta and gamma subunits of a heterotrimeric G protein, which dissociates from the alpha subunit upon guanine nuclotide exchange.	tmpzr1t_l9r_go_relaxed.owl	G-beta/G-gamma complex|heterotrimeric G-protein GTPase, beta-subunit					See also the cellular component term 'heterotrimeric G-protein complex ; GO:0005834'.								cellular_component											owl:Class	
GO:0031389	biolink:NamedThing	Rad17 RFC-like complex	A pentameric protein complex related to replication factor C, which loads a trimeric complex of checkpoint proteins (known as the checkpoint clamp or 9-1-1 complex) onto DNA at damage sites; functions in DNA damage cell cycle checkpoints. In Schizosaccharomyces pombe the subunits are known as Rad17, Rfc2, Rfc3, Rfc4, and Rfc5, while in Saccharomyces cerevisiae the subunits are known as Rad24p, Rfc2p, Rfc3p, Rfc4p, and Rfc5p.	tmpzr1t_l9r_go_relaxed.owl	Rad17-RLC|Rad17-RFC|RFC (Rad17)|Rad24p RFC-like complex													cellular_component											owl:Class	
GO:0042658	biolink:NamedThing	MHC class II protein binding, via antigen binding groove	Binding to the antigen binding groove of major histocompatibility complex class II molecules.	tmpzr1t_l9r_go_relaxed.owl	major histocompatibility complex class II protein binding, via antigen binding groove													molecular_function											owl:Class	
GO:0030896	biolink:NamedThing	checkpoint clamp complex	Conserved heterotrimeric complex of PCNA-like proteins that is loaded onto DNA at sites of DNA damage.	tmpzr1t_l9r_go_relaxed.owl	Rad9-Hus1-Rad1 (9-1-1) clamp complex|CCC					Note that the following subunit names have been used: human RAD9/RAD1/HUS1; S. pombe Rad9/Rad1/Hus1; S. cerevisiae Ddc1p/Rad17p/Mec3p.								cellular_component											owl:Class	
GO:0033569	biolink:NamedThing	lactoferrin transmembrane transporter activity	Enables the transfer of lactoferrin from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0098977	biolink:NamedThing	inhibitory chemical synaptic transmission	Synaptic transmission that results in an inhibitory postsynaptic potential.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0060680	biolink:NamedThing	lateral sprouting involved in ureteric bud morphogenesis	The process in which a branch forms along the side of a ureteric bud.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-06-02T02:44:27Z					biological_process											owl:Class	
GO:1990669	biolink:NamedThing	endoplasmic reticulum-Golgi intermediate compartment (ERGIC) derived vesicle fusion with endoplasmic reticulum membrane	The joining of the lipid bilayer membrane around an ERGIC-derived vesicle to the lipid bilayer membrane of the ER. Such vesicles include COPI-coated transport vesicles involved in retrograde transport.	tmpzr1t_l9r_go_relaxed.owl	endoplasmic reticulum-Golgi intermediate compartment (ERGIC) derived vesicle fusion with ER membrane|ER-Golgi intermediate compartment derived vesicle fusion with ER membrane							bhm	2015-03-02T11:21:43Z					biological_process											owl:Class	
GO:0001854	biolink:NamedThing	complement component C3d binding	Binding to a C3d product of the complement cascade.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1990252	biolink:NamedThing	Syp1 complex	A protein complex that contributes to the endocytic process and bud growth in yeast. It is involved in the precise timing of actin assembly during endocytosis.	tmpzr1t_l9r_go_relaxed.owl	Syp1 dimer							bhm	2013-12-09T14:43:00Z					cellular_component											owl:Class	
GO:0097047	biolink:NamedThing	DNA replication termination region	A chromosomal region that contains fork pausing elements influencing the progression and merging of DNA replication forks.	tmpzr1t_l9r_go_relaxed.owl	TER							pr	2011-05-03T03:38:40Z					cellular_component											owl:Class	
GO:0061909	biolink:NamedThing	autophagosome-lysosome fusion	The process in which autophagosomes, double-membraned vesicles containing cytoplasmic material, fuse with a vacuole (yeast) or lysosome (e.g. mammals and insects). In the case of yeast, inner membrane-bounded structures (autophagic bodies) appear in the vacuole. Fusion provides an acidic environment and digestive function to the interior of the autophagosome.	tmpzr1t_l9r_go_relaxed.owl	autophagosome-vacuole fusion|autophagosome fusion							dph	2017-06-29T17:07:52Z					biological_process											owl:Class	
GO:0003005	biolink:NamedThing	follicular fluid formation in ovarian follicle antrum involved in scattered antral spaces stage	The menstrual cycle process in which one central cavity separating the oocyte/cumulus complex from mural granulosa and theca cells is formed as part of the scattered antral spaces stage of oogenesis.	tmpzr1t_l9r_go_relaxed.owl	follicular fluid formation in ovarian follicle antrum during scattered antral spaces stage													biological_process											owl:Class	
GO:0060098	biolink:NamedThing	membrane reorganization involved in phagocytosis, engulfment	The assembly and arrangement of the plasma membrane that is involved in the internalization of bacteria, immune complexes and other particulate matter or of an apoptotic cell by phagocytosis.	tmpzr1t_l9r_go_relaxed.owl	membrane reorganisation involved in phagocytosis, engulfment													biological_process											owl:Class	
GO:1903074	biolink:NamedThing	TRAIL death-inducing signaling complex assembly	The aggregation, arrangement and bonding together of a set of components to form a TRAIL death-inducing signaling complex.	tmpzr1t_l9r_go_relaxed.owl	TRAIL DISC assembly|TRAIL death-inducing signalling complex formation|TRAIL DISC formation|TRAIL death-inducing signaling complex formation|TRAIL death-inducing signalling complex assembly							bf	2014-05-29T09:47:39Z					biological_process											owl:Class	
GO:0039669	biolink:NamedThing	viral entry into host cell via pilus retraction and membrane fusion	The uptake of a virus into a host cell which occurs via retraction of the viral-bound pilus to bring the virus in contact with the host cell membrane, followed by fusion of the bacteriophage membrane with the host outer membrane.	tmpzr1t_l9r_go_relaxed.owl						For annotation of viral pilus-binding proteins, see also 'viral attachment to host cell pilus ; GO:0039666'.		bf	2013-09-04T14:35:44Z					biological_process											owl:Class	
GO:2000776	biolink:NamedThing	histone H4 acetylation involved in response to DNA damage stimulus	Any histone H4 acetylation that is involved in a response to DNA damage stimulus.	tmpzr1t_l9r_go_relaxed.owl	histone H4 acetylation of cellular DNA damage response|histone H4 acetylation of cellular response to DNA damage stimulus|histone H4 acetylation of response to genotoxic stress|histone H4 acetylation of DNA damage response|histone H4 acetylation of response to DNA damage stimulus							mah	2011-06-22T04:00:54Z					biological_process											owl:Class	
GO:0021908	biolink:NamedThing	retinoic acid receptor signaling pathway involved in spinal cord anterior/posterior pattern formation	The series of molecular signals generated as a consequence of a retinoic acid receptor binding to one of its physiological ligands that results in the spatial identity of regions along the anterior-posterior axis of the spinal cord.	tmpzr1t_l9r_go_relaxed.owl	retinoic acid receptor signalling pathway in spinal cord anterior-posterior patterning													biological_process											owl:Class	
GO:0052619	biolink:NamedThing	coenzyme F420-1:gamma-L-glutamate ligase activity	Catalysis of the reaction: GTP + L-glutamate + factor gamma-F420-1 = GDP + H+ + factor gamma-F420-2 + phosphate.	tmpzr1t_l9r_go_relaxed.owl					RHEA:30523|EC:6.3.2.34|MetaCyc:RXN-8081									molecular_function											owl:Class	
GO:0090017	biolink:NamedThing	anterior neural plate formation	The formation of anterior end of the flat, thickened layer of ectodermal cells known as the neural plate.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-07-29T11:31:35Z					biological_process											owl:Class	
GO:1990619	biolink:NamedThing	histone H3-K9 deacetylation	The modification of histone H3 by the removal of an acetyl group from lysine at position 9 of the histone.	tmpzr1t_l9r_go_relaxed.owl								al	2015-01-23T17:27:16Z					biological_process											owl:Class	
GO:0006283	biolink:NamedThing	transcription-coupled nucleotide-excision repair	The nucleotide-excision repair process that carries out preferential repair of DNA lesions on the actively transcribed strand of the DNA duplex. In addition, the transcription-coupled nucleotide-excision repair pathway is required for the recognition and repair of a small subset of lesions that are not recognized by the global genome nucleotide excision repair pathway.	tmpzr1t_l9r_go_relaxed.owl	TCR|transcription-coupled NER|transcription-coupled repair|TC-NER													biological_process											owl:Class	
GO:0044520	biolink:NamedThing	envenomation resulting in positive regulation of vasoactive intestinal polypeptide receptor activity in other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant positive regulation of the activity of a vasoactive intestinal polypeptide receptor in the bitten organism.	tmpzr1t_l9r_go_relaxed.owl	envenomation resulting in positive regulation of VIP receptor activity in other organism							jl	2012-02-26T11:55:46Z					biological_process											owl:Class	
GO:0120021	biolink:NamedThing	oxysterol transfer activity	Removes oxysterol from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle.	tmpzr1t_l9r_go_relaxed.owl	oxysterol carrier activity|intermembrane oxysterol transfer activity	https://github.com/geneontology/go-ontology/issues/12329						krc	2017-03-17T04:50:30Z					molecular_function											owl:Class	
GO:0002095	biolink:NamedThing	caveolar macromolecular signaling complex	A complex composed of proteins required for beta adrenergic receptor activation of protein kinase A. It includes the Cav 12. subunit of L-type calcium channel, protein kinase A regulatory subunit 2(PKAR2), adenyl cyclase, beta-adrenergic receptor, G-alpha-S, protein phosphatase 2A (PP2A) and caveolin 3 (CAV3).	tmpzr1t_l9r_go_relaxed.owl	caveolar macromolecular signalling complex													cellular_component											owl:Class	
GO:0010772	biolink:NamedThing	meiotic DNA recombinase assembly involved in reciprocal meiotic recombination	The aggregation, arrangement and bonding together of strand exchange proteins (recombinases) to form higher order oligomers on single-stranded DNA resulting in meiotic recombination. Meiotic recombination is the cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0044684	biolink:NamedThing	dihydromethanopterin reductase activity	Catalysis of the reaction: 7,8-dihydromethanopterin + NADPH = 5,6,7,8-tetrahydromethanopterin + NADP.	tmpzr1t_l9r_go_relaxed.owl					RHEA:42804|EC:1.5.99.15			jl	2012-08-15T13:57:55Z					molecular_function											owl:Class	
GO:0042642	biolink:NamedThing	actomyosin, myosin complex part	The myosin part of any complex of actin, myosin, and accessory proteins.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0048849	biolink:NamedThing	neurohypophysis formation	The process that gives rise to neurohypophysis. This process pertains to the initial formation of a structure from unspecified parts. The neurohypophysis is the part of the pituitary gland that secretes hormones involved in blood pressure regulation.	tmpzr1t_l9r_go_relaxed.owl	neurophysis formation|posterior pituitary gland biosynthesis|posterior pituitary formation|neurophysis biosynthesis|posterior pituitary gland formation|posterior pituitary biosynthesis													biological_process											owl:Class	
GO:0030692	biolink:NamedThing	Noc4p-Nop14p complex	A heterodimer associated with precursors of the eukaryotic small ribosomal subunit, including the 90S preribosome; involved in small subunit biogenesis.	tmpzr1t_l9r_go_relaxed.owl	Nop7 subcomplex|Nop7 complex					Noc complexes exhibit a dynamic intranuclear location; consider also annotating to 'nucleolus ; GO:0005730' and/or 'nucleoplasm ; GO:0005654' and/or 'nuclear pore ; GO:0005643'. Note that the term name uses Saccharomyces gene product names because no other names have yet arisen for this complex; the term nevertheless can be used for analogous complexes in other eukaryotes, and the name can be changed if better wording is found.								cellular_component											owl:Class	
GO:0009558	biolink:NamedThing	embryo sac cellularization	The process in which the eight-nucleate single celled female gametophyte develops into the seven-celled female gametophyte. This mature structure contains two synergid cells and an egg cell at the micropylar end, and three antipodal cells at the other end. A binucleate endosperm mother cell is formed at the center. An example of this process is found in Arabidopsis thaliana.	tmpzr1t_l9r_go_relaxed.owl	megagametophyte cellularization|cellularization of the embryo sac|female gametophyte cellularization											GO:0009797		biological_process											owl:Class	
GO:0061379	biolink:NamedThing	inferior colliculus development	The process whose specific outcome is the progression of the inferior colliculus over time, from its formation to the mature structure. The inferior colliculus (IC) (Latin, lower hill) is the principal midbrain nucleus of the auditory pathway and receives input from several more peripheral brainstem nuclei in the auditory pathway, as well as inputs from the auditory cortex. The inferior colliculus has three subdivisions: the central nucleus (CIC), a dorsal cortex (DCIC) by which it is surrounded, and an external cortex (ICX) which is located laterally.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-11-09T09:49:24Z					biological_process											owl:Class	
GO:0031973	biolink:NamedThing	chromoplast intermembrane space	The region between the inner and outer lipid bilayers of a chromoplast envelope.	tmpzr1t_l9r_go_relaxed.owl	chromoplast envelope lumen													cellular_component											owl:Class	
GO:0098548	biolink:NamedThing	cytoplasmic side of Golgi membrane	The side (leaflet) of the Golgi membrane that faces the cytoplasm.	tmpzr1t_l9r_go_relaxed.owl								dos	2013-12-03T10:49:33Z					cellular_component											owl:Class	
GO:0051010	biolink:NamedThing	microtubule plus-end binding	Binding to the plus end of a microtubule.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0019060	biolink:NamedThing	intracellular transport of viral protein in host cell	The directed movement of a viral protein within the host cell.	tmpzr1t_l9r_go_relaxed.owl	viral capsid transport in host cell cytoplasm|intracellular transport of viral proteins in host cell|intracellular transport of viral capsid in host cell|viral capsid transport in host cell nucleus|intracellular transport of viral capsid protein in host cell|cytoplasmic viral capsid transport|intracellular viral protein transport|intracellular viral capsid transport|nuclear viral capsid transport					This term is for annotation of proteins responsible for the movement of individual viral proteins, rather than the whole viral particle.						GO:0046801|GO:0046743|GO:0046742		biological_process											owl:Class	
GO:0003036	biolink:NamedThing	detection of pH by aortic body chemoreceptor signaling	The process in which information about the levels of hydrogen ions are received and are converted to a molecular signal by chemoreceptors in an aortic body.	tmpzr1t_l9r_go_relaxed.owl	detection of pH by aortic body chemoreceptor signalling													biological_process											owl:Class	
GO:0120104	biolink:NamedThing	mitotic actomyosin contractile ring, proximal layer	The region of the mitotic actomyosin ring adjacent to the plasma membrane where membrane bound scaffolds are located.	tmpzr1t_l9r_go_relaxed.owl	actomyosin contractile ring, proximal layer							krc	2017-10-11T22:49:58Z					cellular_component											owl:Class	
GO:0021779	biolink:NamedThing	oligodendrocyte cell fate commitment	The process in which the developmental fate of a cell becomes restricted such that it will develop into an oligodendrocyte.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0090388	biolink:NamedThing	phagosome-lysosome docking involved in apoptotic cell clearance	The initial attachment of a phagosome membrane to a lysosome membrane that occurs as a part of apoptotic cell clearance. Docking requires only that the proteins come close enough to interact and adhere.	tmpzr1t_l9r_go_relaxed.owl								tb	2010-10-27T10:57:39Z					biological_process											owl:Class	
GO:0071521	biolink:NamedThing	Cdc42 GTPase complex	A protein complex formed by the association of the small GTPase Cdc42 with additional proteins. In Schizosaccharomyces the complex contains the Cdc42, Ras1, Scd1, Scd2, andShk1 proteins, and functions in the Ras1-Scd GTPase signalling pathway.	tmpzr1t_l9r_go_relaxed.owl	Ras1-Scd1-Scd2-Cdc42-Shk1 complex							mah	2010-01-07T01:29:12Z					cellular_component											owl:Class	
GO:0015416	biolink:NamedThing	ABC-type phosphonate transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + phosphonate(out) = ADP + phosphate + phosphonate(in). A phosphonate is any salt, anion, or ester of phosphonic acid (HPO(OH)2).	tmpzr1t_l9r_go_relaxed.owl	organic phosphonate transmembrane-transporting ATPase activity|alkylphosphonate transmembrane-transporting ATPase activity|alkylphosphonate ABC transporter activity|phosphonate-transporting ATPase activity|ATPase-coupled alkylphosphonate transmembrane transporter activity|organic phosphonate transmembrane transporter activity|alkylphosphonate transmembrane transporter activity|ATP phosphohydrolase (phosphonate-transporting)|phosphonate ABC transporter|phosphonate transporting ATPase activity|ATPase-coupled organic phosphonate transmembrane transporter activity				MetaCyc:ABC-23-RXN|EC:7.3.2.2|MetaCyc:3.6.3.28-RXN|RHEA:18065							GO:0042917|GO:0102017|GO:0015604		molecular_function											owl:Class	
GO:0000765	biolink:NamedThing	response to pheromone regulating pheromone-induced unidirectional conjugation	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pheromone stimulus that regulates the process of pheromone-induced unidirectional conjugation.	tmpzr1t_l9r_go_relaxed.owl	response to pheromone during pheromone-induced unidirectional													biological_process											owl:Class	
GO:1990461	biolink:NamedThing	detoxification of iron ion	Any process that reduces or removes the toxicity of iron ion. These include transport of iron away from sensitive areas and to compartments or complexes whose purpose is sequestration of iron ion.	tmpzr1t_l9r_go_relaxed.owl								sart	2014-08-19T10:12:46Z					biological_process											owl:Class	
GO:0060641	biolink:NamedThing	mammary gland duct regression in males	The process in which the epithelium of the mammary duct is destroyed in males.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-05-20T04:50:57Z					biological_process											owl:Class	
GO:0003689	biolink:NamedThing	DNA clamp loader activity	Facilitating the opening of the ring structure of the PCNA complex, or any of the related sliding clamp complexes, and their closing around the DNA duplex, driven by ATP hydrolysis.	tmpzr1t_l9r_go_relaxed.owl	PCNA loading complex activity|DNA-protein loading ATPase activity|DNA clamp loading ATPase activity|PCNA loading activity|protein-DNA loading ATPase activity				Reactome:R-HSA-176264|Reactome:R-HSA-174439							GO:0033170		molecular_function											owl:Class	
GO:0097709	biolink:NamedThing	connective tissue replacement	The series of events leading to growth of connective tissue when loss of tissues that are incapable of regeneration occurs, or when fibrinous exudate cannot be adequately cleared.	tmpzr1t_l9r_go_relaxed.owl								pr	2016-05-17T10:49:10Z					biological_process											owl:Class	
GO:0103067	biolink:NamedThing	4alpha-carboxy-5alpha-cholesta-8-en-3beta-ol:NAD(P)+ 3-dehydrogenase (decarboxylating) activity	Catalysis of the reaction: 4alpha-carboxy-5alpha-cholesta-8-en-3beta-ol + NAD(P) = 5alpha-cholesta-8-en-3-one + carbon dioxide + NAD(P)H.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN66-23|RHEA:33447|EC:1.1.1.170									molecular_function											owl:Class	
GO:0034788	biolink:NamedThing	2,3-dihydroxy-2'-carboxybiphenyl 1,2-dioxygenase activity	Catalysis of the reaction: 2,3-dihydroxy-2'-carboxybiphenyl + O2 = 2-hydroxy-6-oxo-6-(2-carboxyphenyl)-hexa-2,4-dienoate + H+.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r1041									molecular_function											owl:Class	
GO:0071821	biolink:NamedThing	FANCM-MHF complex	A protein complex contains the proteins FANCM and MHF, or their orthologs, plays an essential role in DNA remodeling, protects replication forks, and is conserved in eukaryotes.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-09-07T12:08:38Z					cellular_component											owl:Class	
GO:0103010	biolink:NamedThing	gibberellin A53,2-oxoglutarate:oxygen oxidoreductase activity (GA97-forming)	Catalysis of the reaction: gibberellin A53 + 2-oxoglutarate + O2 = gibberellin A97 + succinate + carbon dioxide.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-991									molecular_function											owl:Class	
GO:0016498	biolink:NamedThing	neuromedin K receptor activity	Combining with neuromedin K, the peptide Asp-Met-His-Asp-Phe-Phe-Val-Gly-Leu-Met to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	neurokinin B receptor activity													molecular_function											owl:Class	
GO:0031042	biolink:NamedThing	O-glycan processing, core 6	The stepwise addition of carbohydrate or carbohydrate derivative residues to the initially added O-linked residue (usually GalNAc) to form the core 6 O-glycan structure, GlcNAc-beta-(1->6)-GalNAc.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0052734	biolink:NamedThing	shikimate 3-dehydrogenase (NAD+) activity	Catalysis of the reaction: shikimate + NAD+ = 3-dehydroshikimate + NADH + H+.	tmpzr1t_l9r_go_relaxed.owl	shikimate:NAD(P)(+) oxidoreductase activity|DHS reductase activity|3-dehydroshikimic reductase activity|shikimate:NAD(P)(+) 3-oxidoreductase activity|dehydroshikimic reductase activity|3-dehydroshikimate reductase activity|shikimate oxidoreductase activity				RHEA:17741|KEGG_REACTION:R06847|EC:1.1.1.282			ai	2011-08-16T04:28:23Z					molecular_function											owl:Class	
GO:0007628	biolink:NamedThing	adult walking behavior	The behavior of an adult relating to the progression of that organism along the ground by the process of lifting and setting down each leg.	tmpzr1t_l9r_go_relaxed.owl	adult walking behaviour													biological_process											owl:Class	
GO:0048106	biolink:NamedThing	establishment of thoracic bristle planar orientation	Orientation along the body surface of bristles, sensory organs originating from a sensory organ precursor cell, such that they all point in a uniform direction.	tmpzr1t_l9r_go_relaxed.owl	establishment of body bristle planar orientation													biological_process											owl:Class	
GO:0001588	biolink:NamedThing	dopamine neurotransmitter receptor activity, coupled via Gs	Combining with the neurotransmitter dopamine and activating adenylate cyclase via coupling to Gs to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	dopamine D1 receptor activity|dopamine D5 receptor activity											GO:0001590|GO:0001589		molecular_function											owl:Class	
GO:0102557	biolink:NamedThing	protopanaxadiol 6-hydroxylase activity	Catalysis of the reaction: (20S)-protopanaxadiol + O2 + NADPH(4-) + H+ <=> protopanaxatriol + NADP + H2O.	tmpzr1t_l9r_go_relaxed.owl					RHEA:22272|MetaCyc:RXN-14978|EC:1.14.14.121									molecular_function											owl:Class	
GO:0010244	biolink:NamedThing	response to low fluence blue light stimulus by blue low-fluence system	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the detection of a low fluence blue light stimulus by the blue low-fluence system. Blue light is electromagnetic radiation with a wavelength of between 440 and 500nm. The blue low-fluence system responds to blue light at or below 0.1 micromols/m2. In certain species excitation of the blue low fluence system induces the transcription of a number of nuclear and plastid coded genes.	tmpzr1t_l9r_go_relaxed.owl	response to low fluence blue light|response to low fluence blue light by blf system													biological_process											owl:Class	
GO:0031772	biolink:NamedThing	type 2 hypocretin receptor binding	Binding to a type 2 hypocretin receptor.	tmpzr1t_l9r_go_relaxed.owl	type 2 hypocretin receptor ligand|type 2 orexin receptor binding													molecular_function											owl:Class	
GO:0016038	biolink:NamedThing	absorption of visible light	The reception of a (visible light) photon by a cell, visible light being defined as having a wavelength within the range 380-780 nm.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0047084	biolink:NamedThing	methyltetrahydroprotoberberine 14-monooxygenase activity	Catalysis of the reaction: O2 + NADPH + H+ + (S)-N-methylcanadine = H2O + NADP+ + allocryptopine.	tmpzr1t_l9r_go_relaxed.owl	(S)-N-methylcanadine,NADPH:oxygen oxidoreductase (14-hydroxylating)|methyltetrahydroprotoberberine 14-hydroxylase activity|(S)-cis-N-methyltetrahydroprotoberberine-14-hydroxylase activity|(S)-cis-N-methyltetrahydroberberine 14-monooxygenase activity				EC:1.14.14.97|MetaCyc:1.14.13.37-RXN|RHEA:23684									molecular_function											owl:Class	
GO:0050582	biolink:NamedThing	xylitol oxidase activity	Catalysis of the reaction: xylitol + O2 = xylose + H2O2.	tmpzr1t_l9r_go_relaxed.owl	xylitol:oxygen oxidoreductase activity				MetaCyc:1.1.3.41-RXN|EC:1.1.3.41									molecular_function											owl:Class	
GO:0001886	biolink:NamedThing	endothelial cell morphogenesis	The change in form (cell shape and size) that occurs during the differentiation of an endothelial cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0050642	biolink:NamedThing	2-alpha-hydroxytaxane 2-O-benzoyltransferase activity	Catalysis of the reaction: 10-deacetyl-2-debenzoylbaccatin III + benzoyl-CoA = 10-deacetylbaccatin III + CoA.	tmpzr1t_l9r_go_relaxed.owl	benzoyl-CoA:taxane 2-alpha-O-benzoyltransferase activity|2alpha-hydroxytaxane 2-O-benzoyltransferase activity|2a-hydroxytaxane 2-O-benzoyltransferase activity|benzoyl-CoA:taxan-2alpha-ol O-benzoyltransferase activity|2-debenzoyl-7,13-diacetylbaccatin III-2-O-benzoyl transferase activity|benzoyl-CoA:taxane 2alpha-O-benzoyltransferase activity				RHEA:18741|EC:2.3.1.166|MetaCyc:2.3.1.166-RXN|KEGG_REACTION:R06310									molecular_function											owl:Class	
GO:0106242	biolink:NamedThing	kolavenyl diphosphate synthase activity	Catalysis of the reaction: all-trans-geranylgeranyl diphosphate = (+)-kolavenyl diphosphate.	tmpzr1t_l9r_go_relaxed.owl					EC:5.5.1.29|RHEA:54676			hjd	2019-12-19T18:31:00Z					molecular_function											owl:Class	
GO:1990562	biolink:NamedThing	syndecan-syntenin-ALIX complex	An exosome complex that is assembled in the multivesicular body (MVB) membrane and chaperoned to the exosome by the ESCRT-III machinery.	tmpzr1t_l9r_go_relaxed.owl	exosome complex					An example of this is SCD1 in human (UniProt symbol P18827) in PMID:22660413 (inferred from physical interaction).		bhm	2014-11-25T16:30:47Z					cellular_component											owl:Class	
GO:0030847	biolink:NamedThing	termination of RNA polymerase II transcription, exosome-dependent	The process in which transcription of nonpolyadenylated RNA polymerase II transcripts is terminated; coupled to the maturation of the RNA 3'-end.	tmpzr1t_l9r_go_relaxed.owl	transcription termination from Pol II promoter, poly(A)-independent|termination of RNA polymerase II transcription, poly(A)-independent|transcription termination from Pol II promoter, RNA polymerase(A)-independent													biological_process											owl:Class	
GO:0035868	biolink:NamedThing	alphav-beta3 integrin-HMGB1 complex	A protein complex that consists of an alphav-beta3 integrin complex bound to high mobility group box 1 protein.	tmpzr1t_l9r_go_relaxed.owl	alphav-beta3 integrin-high mobility group box 1 complex							bf	2011-05-25T03:07:24Z					cellular_component											owl:Class	
GO:0046465	biolink:NamedThing	dolichyl diphosphate metabolic process	The chemical reactions and pathways involving dolichyl diphosphate, a diphosphorylated dolichol derivative. In eukaryotes, these function as carriers of mono- and oligosaccharide residues in the glycosylation of lipids and proteins within intracellular membranes.	tmpzr1t_l9r_go_relaxed.owl	dolichyl diphosphate metabolism													biological_process											owl:Class	
GO:0004777	biolink:NamedThing	succinate-semialdehyde dehydrogenase (NAD+) activity	Catalysis of the reaction: succinate semialdehyde + NAD+ + H2O = succinate + NADH + H+.	tmpzr1t_l9r_go_relaxed.owl	succinyl semialdehyde dehydrogenase activity|succinate semialdehyde:NAD+ oxidoreductase activity|succinate-semialdehyde:NAD+ oxidoreductase activity|succinic semialdehyde dehydrogenase activity|succinate-semialdehyde dehydrogenase activity|succinate semialdehyde dehydrogenase activity				Reactome:R-HSA-888548|EC:1.2.1.24|MetaCyc:SUCCINATE-SEMIALDEHYDE-DEHYDROGENASE-RXN|RHEA:13217							GO:0008952		molecular_function											owl:Class	
GO:0008482	biolink:NamedThing	sulfite oxidase activity	Catalysis of the reaction: H(2)O + O(2) + sulfite = H(2)O(2) + H(+) + sulfate.	tmpzr1t_l9r_go_relaxed.owl	sulfite:oxygen oxidoreductase activity|sulphite oxidase activity				KEGG_REACTION:R00533|MetaCyc:SULFITE-OXIDASE-RXN|MetaCyc:PWY-5326|EC:1.8.3.1|RHEA:24600|Reactome:R-HSA-1614544									molecular_function											owl:Class	
GO:0047003	biolink:NamedThing	dTDP-6-deoxy-L-talose 4-dehydrogenase activity	Catalysis of the reaction: dTDP-6-deoxy-L-talose + NADP(+) = dTDP-4-dehydro-6-deoxy-L-mannose + H(+) + NADPH.	tmpzr1t_l9r_go_relaxed.owl	TDP-6-deoxy-L-talose dehydrogenase activity|thymidine diphospho-6-deoxy-L-talose dehydrogenase activity|dTDP-6-deoxy-L-talose:NADP+ 4-oxidoreductase activity|dTDP-6-deoxy-L-talose dehydrogenase (4-reductase)				RHEA:23648|KEGG_REACTION:R02776|EC:1.1.1.134|MetaCyc:1.1.1.134-RXN									molecular_function											owl:Class	
GO:0035593	biolink:NamedThing	positive regulation of Wnt signaling pathway by establishment of Wnt protein localization to extracellular region	Any process that activates or increases the frequency, rate or extent of the Wnt signaling pathway by the directed movement of a Wnt protein within the extracellular region.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of Wnt-activated signaling pathway by establishment of Wnt protein localization to extracellular region|positive regulation of Wnt diffusion|positive regulation of Wnt receptor signalling pathway by establishment of Wnt protein localization in extracellular region|positive regulation of Wnt receptor signaling pathway by establishment of Wnt protein localisation in extracellular region|positive regulation of Wnt receptor signaling pathway by establishment of Wnt protein localization to extracellular region|positive regulation of Wnt receptor signaling pathway by establishment of Wnt protein localization in extracellular region|positive regulation of Wnt signaling range							bf	2010-11-09T10:29:44Z					biological_process											owl:Class	
GO:0021962	biolink:NamedThing	vestibulospinal tract morphogenesis	Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the vestibular nucleus of the pons towards target cells in the spinal cord.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1990340	biolink:NamedThing	laminin-15 complex	A laminin complex composed of alpha5, beta2 and gamma3 polypeptide chains.	tmpzr1t_l9r_go_relaxed.owl	laminin-523							bhm	2014-03-20T23:48:25Z					cellular_component											owl:Class	
GO:0060488	biolink:NamedThing	orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis	The process in which a lung bud bifurcates perpendicular to the plane of the previous bud.	tmpzr1t_l9r_go_relaxed.owl	perpendicular dichotomous subdivision of terminal units involved in lung branching morphogenesis													biological_process											owl:Class	
GO:0036348	biolink:NamedThing	hydantoin racemase activity	Catalysis of the reaction: D-5-monosubstituted hydantoin = L-5-monosubstituted hydantoin.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-9781|EC:5.1.99.5|KEGG_REACTION:R09704|RHEA:46624			bf	2012-09-19T10:47:56Z					molecular_function											owl:Class	
GO:0102210	biolink:NamedThing	rhamnogalacturonan endolyase activity	Catalysis of the reaction: H2O + a rhamnogalacturonan type I <=> [rhamnogalacturonan I oligosaccharide]-alpha-L-rhamnose + 4-deoxy-4,5-unsaturated D-galactopyranosyluronate-[rhamnogalacturonan I oligosaccharide].	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-12173|EC:4.2.2.23									molecular_function											owl:Class	
GO:0071501	biolink:NamedThing	cellular response to sterol depletion	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating deprivation of sterols. Sterols are a group of steroids characterized by the presence of one or more hydroxyl groups and a hydrocarbon side-chain in the molecule.	tmpzr1t_l9r_go_relaxed.owl	cellular sterol depletion response							mah	2009-12-18T02:54:14Z					biological_process											owl:Class	
GO:0031768	biolink:NamedThing	ghrelin receptor binding	Binding to a ghrelin receptor.	tmpzr1t_l9r_go_relaxed.owl	type 1 growth hormone secretagogue GH-releasing peptide receptor binding|ghrelin receptor ligand													molecular_function											owl:Class	
GO:0051566	biolink:NamedThing	anthocyanidin-3-glucoside rhamnosyltransferase activity	Catalysis of the reaction: anthocyanidin 3-glucoside + UDP-rhamnose = anthocyanidin 3-rutinoside + UDP.	tmpzr1t_l9r_go_relaxed.owl	3RT activity|anthocyanidin 3-glucoside-rhamnosyltransferase activity													molecular_function											owl:Class	
GO:0050315	biolink:NamedThing	synephrine dehydratase activity	Catalysis of the reaction: synephrine = (4-hydroxyphenyl)acetaldehyde + methylammonium.	tmpzr1t_l9r_go_relaxed.owl	1-(4-hydroxyphenyl)-2-(methylamino)ethanol hydro-lyase (methylamine-forming)				RHEA:32203|EC:4.2.1.88|KEGG_REACTION:R03359|MetaCyc:SYNEPHRINE-DEHYDRATASE-RXN									molecular_function											owl:Class	
GO:0036192	biolink:NamedThing	3-hydroxyindolin-2-one monooxygenase activity	Catalysis of the reaction: 3-hydroxyindolin-2-one + NAD(P)H + H+ + O2 = 2-hydroxy-2H-1,4-benzoxazin-3(4H)-one + NAD(P)+ + H2O.	tmpzr1t_l9r_go_relaxed.owl	3-hydroxyindolin-2-one,NAD(P)H:oxygen oxidoreductase (2-hydroxy-2H-1,4-benzoxazin-3(4H)-one-forming)				EC:1.14.14.109|RHEA:31927|KEGG_REACTION:R07422			bf	2012-04-19T11:45:33Z					molecular_function											owl:Class	
GO:0120171	biolink:NamedThing	Cdc24p-Far1p-Gbetagamma complex	A complex that forms at the cell cortex in response to pheromone treatment and is required for the polarized growth of haploid yeast cells towards a mating partner during yeast mating. In the yeast Saccharomyces cerevisiae, this complex consists of Cdc24p, Far1p, Ste4p (G-protein beta subunit) and Ste18p (G-protein gamma subunit).	tmpzr1t_l9r_go_relaxed.owl	Cdc24p-Far1p-BG complex|CDC24-FAR1-Gbetagamma complex|CDC24-FAR1-BG complex							krc	2018-05-31T17:11:20Z					cellular_component											owl:Class	
GO:0033983	biolink:NamedThing	diaminobutyrate decarboxylase activity	Catalysis of the reaction: L-2,4-diaminobutyrate + H(+) = 1,3-diaminopropane + CO(2).	tmpzr1t_l9r_go_relaxed.owl	DABA DC|L-2,4-diaminobutyrate decarboxylase activity|L-2,4-diaminobutanoate carboxy-lyase (propane-1,3-diamine-forming) activity|L-2,4-diaminobutanoate carboxy-lyase activity				KEGG_REACTION:R07650|EC:4.1.1.86|RHEA:15689|MetaCyc:4.1.1.86-RXN									molecular_function											owl:Class	
GO:0051060	biolink:NamedThing	pullulanase activity	Catalysis of the hydrolysis of (1,6)-alpha-D-glucosidic linkages in pullulan (a linear polymer of alpha-(1,6)-linked maltotriose units) and in amylopectin and glycogen, and the a- and b-limit dextrins of amylopectin and glycogen.	tmpzr1t_l9r_go_relaxed.owl	debranching enzyme activity|R-enzyme|pullulan 6-glucanohydrolase activity|pullulan alpha-1,6-glucanohydrolase activity|limit dextrinase|alpha-dextrin endo-1,6-alpha-glucosidase activity|bacterial debranching enzyme|amylopectin 6-glucanohydrolase activity				EC:3.2.1.41|MetaCyc:RXN-1824									molecular_function											owl:Class	
GO:0090711	biolink:NamedThing	FMN hydrolase activity	Catalysis of the reaction: FMN + H2O = riboflavin + phosphate.	tmpzr1t_l9r_go_relaxed.owl								tb	2016-10-21T16:27:34Z					molecular_function											owl:Class	
GO:0047330	biolink:NamedThing	polyphosphate-glucose phosphotransferase activity	Catalysis of the reaction: beta-D-glucose + long chain polyphosphate = glucose-6-phosphate + long chain polyphosphate.	tmpzr1t_l9r_go_relaxed.owl	polyphosphate glucokinase activity|polyphosphate:D-glucose 6-phosphotransferase activity|polyphosphate-glucose 6-phosphotransferase activity|polyphosphate-D-(+)-glucose-6-phosphotransferase activity				MetaCyc:2.7.1.63-RXN|RHEA:22036|EC:2.7.1.63									molecular_function											owl:Class	
GO:0004149	biolink:NamedThing	dihydrolipoyllysine-residue succinyltransferase activity	Catalysis of the reaction: succinyl-CoA + dihydrolipoamide = CoA + S-succinyldihydrolipoamide.	tmpzr1t_l9r_go_relaxed.owl	dihydrolipoamide succinyltransferase activity|lipoate succinyltransferase (Escherichia coli) activity|lipoate succinyltransferase activity|dihydrolipoic transsuccinylase activity|succinyl-CoA:enzyme-6-N-(dihydrolipoyl)lysine S-succinyltransferase activity|dihydrolipoamide S-succinyltransferase activity|succinyl-CoA:enzyme-N6-(dihydrolipoyl)lysine S-succinyltransferase activity|lipoic transsuccinylase activity|dihydrolipolyl transsuccinylase activity|enzyme-dihydrolipoyllysine:succinyl-CoA S-succinyltransferase activity|lipoyl transsuccinylase activity|dihydrolipoyl transsuccinylase activity|succinyl-CoA:dihydrolipoamide S-succinyltransferase activity|succinyl-CoA:dihydrolipoate S-succinyltransferase activity				RHEA:15213|EC:2.3.1.61									molecular_function											owl:Class	
GO:1990143	biolink:NamedThing	CoA-synthesizing protein complex	A multisubunit complex likely involved in the synthesis of coenzyme A (CoA). In S. cerevisiae, the complex consists of at least Cab2, Cab3, Cab4 and Cab5 but may also include Sis2 and Vhs3. The latter subunits are shared by the GO:0071513 phosphopantothenoylcysteine decarboxylase complex that catalyses the third step of the coenzyme A (CoA) biosynthetic pathway.	tmpzr1t_l9r_go_relaxed.owl	coenzyme A-synthesizing protein complex|CoA-SPC							rb	2013-07-18T22:30:20Z					cellular_component											owl:Class	
GO:0016762	biolink:NamedThing	xyloglucan:xyloglucosyl transferase activity	Catalysis of the cleavage of a beta-(1->4) bond in the backbone of a xyloglucan and transfers the xyloglucanyl segment on to O-4 of the non-reducing terminal glucose residue of an acceptor, which can be a xyloglucan or an oligosaccharide of xyloglucan.	tmpzr1t_l9r_go_relaxed.owl	endoxyloglucan transferase activity|xyloglucan endotransglucosylase activity|xyloglucan:xyloglucan xyloglucanotransferase activity|endo-xyloglucan transferase activity				EC:2.4.1.207|MetaCyc:2.4.1.207-RXN							GO:0080039		molecular_function											owl:Class	
GO:0140692	biolink:NamedThing	very long-chain fatty acid omega-hydroxylase activity	Catalysis of the reaction: an omega-methyl-very-long-chain fatty acid + O2 + reduced [NADPH-hemoprotein reductase] = an omega-hydroxy-very-long-chain fatty acid + H+ + H2O + oxidized [NADPH-hemoprotein reductase].	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/21925						pg	2021-08-05T07:41:17Z					molecular_function											owl:Class	
GO:0043257	biolink:NamedThing	laminin-8 complex	A laminin complex composed of alpha4, beta1 and gamma1 polypeptide chains.	tmpzr1t_l9r_go_relaxed.owl	laminin-411 complex													cellular_component											owl:Class	
GO:0030596	biolink:NamedThing	alpha-L-rhamnosidase activity	Catalysis of the hydrolysis of terminal non-reducing alpha-L-rhamnose residues in alpha-L-rhamnosides.	tmpzr1t_l9r_go_relaxed.owl	alpha-L-rhamnoside rhamnohydrolase activity|alpha-L-rhamnosidase T|alpha-L-rhamnosidase N				MetaCyc:3.2.1.40-RXN|EC:3.2.1.40									molecular_function											owl:Class	
GO:0050620	biolink:NamedThing	phycocyanobilin:ferredoxin oxidoreductase activity	Catalysis of the reaction: (3Z)-phycocyanobilin + oxidized ferredoxin = biliverdin IXa + reduced ferredoxin.	tmpzr1t_l9r_go_relaxed.owl	(3Z)-phycocyanobilin:ferredoxin oxidoreductase activity				EC:1.3.7.5|MetaCyc:1.3.7.5-RXN|RHEA:15309									molecular_function											owl:Class	
GO:0070773	biolink:NamedThing	protein-N-terminal glutamine amidohydrolase activity	Catalysis of the reaction: protein-N-terminal-L-glutamine + H2O = protein-N-terminal-L-glutamate + NH3. This reaction is the deamidation of an N-terminal glutamine residue of a protein.	tmpzr1t_l9r_go_relaxed.owl	NtQ-amidase activity							mah	2009-06-30T11:34:08Z					molecular_function											owl:Class	
GO:0070554	biolink:NamedThing	synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex	A SNARE complex that contains synaptobrevin 2 (VAMP2), SNAP-25, syntaxin 3, and a complexin (or orthologs thereof).	tmpzr1t_l9r_go_relaxed.owl	SNARE complex (Stx3, Snap25, Vamp2, Cplx1)|Stx3-Snap25-Vamp2-Cplx1 complex													cellular_component											owl:Class	
GO:0070411	biolink:NamedThing	I-SMAD binding	Binding to an inhibitory SMAD signaling protein.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0018814	biolink:NamedThing	phenylacetaldoxime dehydratase activity	Catalysis of the reaction: (trans)-phenylacetaldoxime = H(2)O + phenylacetonitrile.	tmpzr1t_l9r_go_relaxed.owl	OxdB|(Z)-phenylacetaldehyde-oxime hydro-lyase activity|arylacetaldoxime dehydratase activity|PAOx dehydratase activity|(Z)-phenylacetaldehyde-oxime hydro-lyase (phenylacetonitrile-forming) activity				MetaCyc:4.99.1.7-RXN|RHEA:20069|KEGG_REACTION:R07638|EC:4.99.1.7|UM-BBD_reactionID:r0697									molecular_function											owl:Class	
GO:0102855	biolink:NamedThing	1-18:1-2-18:2-phosphatidylcholine desaturase activity	Catalysis of the reaction: 1-18:1-2-18:2-phosphatidylcholine + O2 + a reduced electron acceptor <=> 1-18:2-2-18:2-sn-glycerol-3-phosphocholine + 2 H2O + an oxidized electron acceptor.	tmpzr1t_l9r_go_relaxed.owl					RHEA:46332|EC:1.14.19.22|MetaCyc:RXN-8322									molecular_function											owl:Class	
GO:0047434	biolink:NamedThing	indolepyruvate decarboxylase activity	Catalysis of the reaction: indolepyruvate = CO2 + indole acetaldehyde.	tmpzr1t_l9r_go_relaxed.owl	3-(indol-3-yl)pyruvate carboxy-lyase [(2-indol-3-yl)acetaldehyde-forming]|indole-3-pyruvate decarboxylase activity|3-(indol-3-yl)pyruvate carboxy-lyase activity|indol-3-yl-pyruvate carboxy-lyase activity				RHEA:18017|MetaCyc:4.1.1.74-RXN|EC:4.1.1.74									molecular_function											owl:Class	
GO:0042152	biolink:NamedThing	RNA-mediated DNA recombination	The reverse transcription of an RNA molecule followed by recombination between the resultant cDNA and its homologous chromosomal allele.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:2001078	biolink:NamedThing	(1->6)-beta-D-glucan binding	Binding to (1->6)-beta-D-glucan.	tmpzr1t_l9r_go_relaxed.owl	beta-1,6-D-glucan binding|beta-1->6-D-glucan binding|(1,6)-beta-D-glucan binding|1,6-beta-D-glucan binding|1->6-beta-D-glucan binding|beta-(1->6)-D-glucan binding|beta-(1,6)-D-glucan binding							jl	2011-09-15T01:12:50Z					molecular_function											owl:Class	
GO:1903608	biolink:NamedThing	protein localization to cytoplasmic stress granule	A process in which a protein is transported to, or maintained in, a location within a cytoplasmic stress granule.	tmpzr1t_l9r_go_relaxed.owl	protein localization in cytoplasmic stress granule|protein localisation in cytoplasmic stress granule|protein localisation to cytoplasmic stress granule|protein localization to stress granule							mah	2014-11-14T16:20:32Z					biological_process											owl:Class	
GO:0061952	biolink:NamedThing	midbody abscission	The process by which the midbody, the cytoplasmic bridge that connects the two prospective daughter cells, is severed at the end of mitotic cytokinesis, resulting in two separate daughter cells.	tmpzr1t_l9r_go_relaxed.owl	cell separation during cytokinesis|cytokinetic abscission							dph	2017-11-07T19:44:37Z					biological_process											owl:Class	
GO:0102399	biolink:NamedThing	dTDP-3-N-methylamino-4-oxo-2,3,6-trideoxy-alpha-D-glucose N-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine  + dTDP-3-N-methylamino-4-oxo-2,3,6-trideoxy-alpha-D-glucose <=> S-adenosyl-L-homocysteine  + dTDP-3-N,N-dimethylamino-4-oxo-2,3,6-trideoxy-alpha-D-glucose + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-13658									molecular_function											owl:Class	
GO:0008929	biolink:NamedThing	methylglyoxal synthase activity	Catalysis of the reaction: glycerone phosphate = methylglyoxal + phosphate.	tmpzr1t_l9r_go_relaxed.owl	glycerone-phosphate phospho-lyase (methylglyoxal-forming)|glycerone-phosphate phospho-lyase activity|methylglyoxal synthetase activity				MetaCyc:METHGLYSYN-RXN|EC:4.2.3.3|KEGG_REACTION:R01016|RHEA:17937									molecular_function											owl:Class	
GO:0030962	biolink:NamedThing	peptidyl-arginine dihydroxylation to peptidyl-3,4-dihydroxy-L-arginine	The dihydroxylation of peptidyl-arginine to form peptidyl-3,4-dihydroxy-L-arginine.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0369									biological_process											owl:Class	
GO:0097046	biolink:NamedThing	replication fork progression beyond termination site	Regulation of DNA replication by a mechanism that allows a DNA replication fork to progress beyond a termination site, which is a region containing fork pausing elements that influence the progression and merging of DNA replication forks.	tmpzr1t_l9r_go_relaxed.owl								pr	2011-05-03T03:34:01Z					biological_process											owl:Class	
GO:0004826	biolink:NamedThing	phenylalanine-tRNA ligase activity	Catalysis of the reaction: ATP + L-phenylalanine + tRNA(Phe) = AMP + diphosphate + L-phenylalanyl-tRNA(Phe).	tmpzr1t_l9r_go_relaxed.owl	phenylalanine translase activity|phenylalanyl-tRNA synthetase activity|phenylalanyl-transfer RNA ligase activity|phenylalanine-tRNA synthetase activity|phenylalanyl-transfer RNA synthetase activity|phenylalanyl-tRNA ligase activity|L-phenylalanine:tRNAPhe ligase (AMP-forming) activity|phenylalanyl-transfer ribonucleate synthetase activity|L-phenylalanyl-tRNA synthetase activity				EC:6.1.1.20|RHEA:19413|Reactome:R-HSA-380203|MetaCyc:PHENYLALANINE--TRNA-LIGASE-RXN|Reactome:R-HSA-379848									molecular_function											owl:Class	
GO:0070221	biolink:NamedThing	sulfide oxidation, using sulfide:quinone oxidoreductase	A sulfide oxidation process that proceeds via the reaction catalyzed by sulfide:quinone oxidoreductase.	tmpzr1t_l9r_go_relaxed.owl	sulfide oxidation, using sulfide-quinone reductase|sulphide oxidation, using sulfide:quinone oxidoreductase				MetaCyc:P222-PWY									biological_process											owl:Class	
GO:0009819	biolink:NamedThing	drought recovery	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of prolonged deprivation of water that restores that organism to a normal (non-stressed) condition.	tmpzr1t_l9r_go_relaxed.owl	drought tolerance													biological_process											owl:Class	
GO:0031043	biolink:NamedThing	O-glycan processing, core 7	The stepwise addition of carbohydrate or carbohydrate derivative residues to the initially added O-linked residue (usually GalNAc) to form the core 7 O-glycan structure, GalNAc-alpha-(1->6)-GalNAc.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0090528	biolink:NamedThing	smooth septate junction assembly	The assembly of a smooth septate junction, a septate junction that lacks the regular arrays of electron-dense septae found in pleated septate junctions.	tmpzr1t_l9r_go_relaxed.owl								tb	2013-02-05T14:47:40Z					biological_process											owl:Class	
GO:0004815	biolink:NamedThing	aspartate-tRNA ligase activity	Catalysis of the reaction: ATP + L-aspartate + tRNA(Asp) = AMP + diphosphate + L-aspartyl-tRNA(Asp).	tmpzr1t_l9r_go_relaxed.owl	aspartyl ribonucleic synthetase activity|aspartyl-transfer RNA synthetase activity|aspartyl-tRNA synthetase activity|aspartyl-transfer ribonucleic acid synthetase activity|aspartic acid translase activity|aspartyl ribonucleate synthetase activity|L-aspartate:tRNAAsp ligase (AMP-forming)				Reactome:R-HSA-380229|EC:6.1.1.12|MetaCyc:ASPARTATE--TRNA-LIGASE-RXN|RHEA:19649|Reactome:R-HSA-379867									molecular_function											owl:Class	
GO:0047948	biolink:NamedThing	glutarate-CoA ligase activity	Catalysis of the reaction: ATP + CoA + glutarate = ADP + glutaryl-CoA + H(+) + phosphate.	tmpzr1t_l9r_go_relaxed.owl	glutarate:CoA ligase (ADP-forming)|glutaryl coenzyme A synthetase activity|glutaryl-CoA synthetase activity				MetaCyc:GLUTARATE--COA-LIGASE-RXN|KEGG_REACTION:R02402|EC:6.2.1.6|RHEA:14169									molecular_function											owl:Class	
GO:0022876	biolink:NamedThing	protein-N(PI)-phosphohistidine-galactosamine phosphotransferase system transporter activity	Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + galactosamine(out) = protein histidine + galactosamine phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.	tmpzr1t_l9r_go_relaxed.owl	galactosamine PTS transporter activity													molecular_function											owl:Class	
GO:0047941	biolink:NamedThing	glucuronolactone reductase activity	Catalysis of the reaction: L-gulono-1,4-lactone + NADP(+) = D-glucurono-3,6-lactone + H(+) + NADPH.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:GLUCURONOLACTONE-REDUCTASE-RXN|KEGG_REACTION:R03183|EC:1.1.1.20|RHEA:18925									molecular_function											owl:Class	
GO:0102935	biolink:NamedThing	gypsogenin-UDP-glucosyltransferase activity	Catalysis of the reaction: UDP-alpha-D-glucose + gypsogenin = gypsogenin-28-beta-D-glucoside + UDP.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-9012									molecular_function											owl:Class	
GO:1990155	biolink:NamedThing	Dsc E3 ubiquitin ligase complex assembly	The aggregation, arrangement and bonding together of a set of components to form a Dsc E3 ubiquitin ligase complex, an E3 ubiquitin ligase complex localized to the ER and Golgi membrane.	tmpzr1t_l9r_go_relaxed.owl	Dsc complex assembly							mah	2013-08-01T14:19:19Z					biological_process											owl:Class	
GO:0016084	biolink:NamedThing	myostimulatory hormone activity	The action characteristic of myostimulatory hormone, a peptide hormone that stimulates muscle contraction.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0050527	biolink:NamedThing	poly(3-hydroxyoctanoate) depolymerase activity	Catalysis of the reaction: H2O + poly[(R)-3-hydroxyoctanoate](n) = poly[(R)-3-hydroxyoctanoate](x) + poly[(R)-3-hydroxyoctanoate](n-x); x is 1-5.	tmpzr1t_l9r_go_relaxed.owl	poly[(R)-3-hydroxyoctanoate] hydrolase activity|poly{oxycarbonyl[(R)-2-pentylethylene]} hydrolase activity|poly(HAMCL) depolymerase activity|PHA depolymerase activity|poly((R)-3-hydroxyoctanoate) hydrolase activity|poly(HA) depolymerase activity|poly[(R)-hydroxyalkanoic acid] depolymerase|poly(HA(MCL)) depolymerase activity|PHO depolymerase activity|poly(3HO) depolymerase activity|poly((R)-hydroxyalkanoic acid) depolymerase activity				MetaCyc:3.1.1.76-RXN|EC:3.1.1.76									molecular_function											owl:Class	
GO:0106325	biolink:NamedThing	acetylgalactosaminyl-O-glycosyl-seryl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity	Catalysis of the reaction: 3-O-[N-acetyl-beta-D-glucosaminyl-(1->3)-N-acetyl-alpha-D-galactosaminyl]-L-seryl-[protein] + UDP-N-acetyl-alpha-D-glucosamine = 3-O-[N-acetyl-beta-D-glucosaminyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->6)]-N-acetyl-alpha-D-galactosaminyl]-L-seryl-[protein] + H(+) + UDP.	tmpzr1t_l9r_go_relaxed.owl					RHEA:56188|EC:2.4.1.148			hjd	2020-09-30T13:37:55Z					molecular_function											owl:Class	
GO:0070449	biolink:NamedThing	elongin complex	A transcription elongation factor complex that suppresses RNA polymerase II pausing, and may act by promoting proper alignment of the 3'-end of nascent transcripts with the polymerase catalytic site. Consists of a transcriptionally active Elongin A subunit (about 100 kDa) and two smaller Elongin B (about 18 kDa) and Elongin C (about 15 kDa) subunits.	tmpzr1t_l9r_go_relaxed.owl	transcription factor B (SIII) complex|transcription elongation factor SIII complex|elongin (SIII) complex					See also the cellular component terms 'cyclin-dependent protein kinase activating kinase holoenzyme complex ; GO:0019907' and 'DNA-directed RNA polymerase II, holoenzyme ; GO:0016591'.								cellular_component											owl:Class	
GO:0047008	biolink:NamedThing	pregnan-21-ol dehydrogenase (NADP+) activity	Catalysis of the reaction: NADP(+) + pregnan-21-ol = H(+) + NADPH + pregnan-21-al.	tmpzr1t_l9r_go_relaxed.owl	21-hydroxy steroid (nicotinamide adenine dinucleotide phosphate) dehydrogenase activity|21-hydroxy steroid dehydrogenase activity|21-hydroxysteroid dehydrogenase (NADP+) activity|NADP-21-hydroxysteroid dehydrogenase activity|21-hydroxysteroid:NADP+ 21-oxidoreductase activity|21-hydroxy steroid dehydrogenase (nicotinamide adenine dinucleotide phosphate) activity				KEGG_REACTION:R03044|EC:1.1.1.151|MetaCyc:1.1.1.151-RXN|RHEA:23712									molecular_function											owl:Class	
GO:0050930	biolink:NamedThing	induction of positive chemotaxis	Any process that initiates the directed movement of a motile cell or organism towards a higher concentration in a concentration gradient of a specific chemical.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0103026	biolink:NamedThing	fructose-1-phosphatase activity	Catalysis of the reaction: beta-D-fructofuranose 1-phosphate + H2O <=> beta-D-fructofuranose + hydrogenphosphate.	tmpzr1t_l9r_go_relaxed.owl					RHEA:35603|MetaCyc:RXN0-5186									molecular_function											owl:Class	
GO:0003852	biolink:NamedThing	2-isopropylmalate synthase activity	Catalysis of the reaction: 3-methyl-2-oxobutanoate + acetyl-CoA + H(2)O = (2S)-2-isopropylmalate + CoA + H(+).	tmpzr1t_l9r_go_relaxed.owl	alpha-isopropylmalate synthetase activity|isopropylmalate synthase activity|alpha-isopropylmalate synthase activity|isopropylmalate synthetase activity|alpha-IPM synthetase activity|3-carboxy-3-hydroxy-4-methylpentanoate 3-methyl-2-oxobutanoate-lyase (CoA-acetylating) activity|acetyl-CoA:3-methyl-2-oxobutanoate C-acetyltransferase (thioester-hydrolysing, carboxymethyl-forming)|alpha-isopropylmalic synthetase activity				EC:2.3.3.13|MetaCyc:2-ISOPROPYLMALATESYN-RXN|RHEA:21524|KEGG_REACTION:R01213	Note that this function was formerly EC:4.1.3.12.								molecular_function											owl:Class	
GO:0102544	biolink:NamedThing	ornaline synthase activity	Catalysis of the reaction: L-ornithinium(1+) + 2-oxoglutarate + NADPH + H+ <=> ornaline + NADP + H2O.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-14880									molecular_function											owl:Class	
GO:0034532	biolink:NamedThing	2-hydroxy-7-hydroxymethylchromene-2-carboxylate isomerase activity	Catalysis of the reaction: 2-hydroxy-7-hydroxymethylchromene-2-carboxylate = 2-hydroxy-4-hydroxymethylbenzalpyruvate.	tmpzr1t_l9r_go_relaxed.owl					EC:5.3.99.-|UM-BBD_reactionID:r0765									molecular_function											owl:Class	
GO:0047070	biolink:NamedThing	3-carboxyethylcatechol 2,3-dioxygenase activity	Catalysis of the reaction: O2 + 3-(2,3-dihydroxyphenyl)propanoate = 2-hydroxy-6-oxonona-2,4-diene-1,9-dioate.	tmpzr1t_l9r_go_relaxed.owl	2,3-dihydroxy-beta-phenylpropionic dioxygenase activity|3-(2,3-dihydroxyphenyl)propanoate:oxygen 1,2-oxidoreductase activity|2,3-dihydroxy-beta-phenylpropionate oxygenase activity|3-(2,3-dihydroxyphenyl)propanoate:oxygen 1,2-oxidoreductase (decyclizing)				RHEA:23840|EC:1.13.11.16|MetaCyc:1.13.11.16-RXN							GO:0008669		molecular_function											owl:Class	
GO:0033831	biolink:NamedThing	kojibiose phosphorylase activity	Catalysis of the reaction: kojibiose + phosphate = beta-D-glucose 1-phosphate + D-glucose.	tmpzr1t_l9r_go_relaxed.owl	2-alpha-D-glucosyl-D-glucose:phosphate beta-D-glucosyltransferase activity				EC:2.4.1.230|KEGG_REACTION:R07264|MetaCyc:2.4.1.230-RXN|RHEA:11176									molecular_function											owl:Class	
GO:0008096	biolink:NamedThing	juvenile hormone epoxide hydrolase activity	Catalysis of the hydrolysis of the epoxide in a juvenile hormone to the corresponding diol.	tmpzr1t_l9r_go_relaxed.owl					EC:3.3.2.-									molecular_function											owl:Class	
GO:0001730	biolink:NamedThing	2'-5'-oligoadenylate synthetase activity	Catalysis of the reaction: ATP = pppA(2'p5'A)n oligomers. This reaction requires the binding of double-stranded RNA.	tmpzr1t_l9r_go_relaxed.owl	2-5A synthetase activity|2'-5' oligoadenylate synthetase activity|oligo-2',5'-adenylate synthetase activity|(2-5')oligo(A) synthetase activity				EC:2.7.7.84|Reactome:R-HSA-8985104|Reactome:R-HSA-8983680|MetaCyc:RXN-13648|Reactome:R-HSA-8985091|MetaCyc:RXN-10798|RHEA:34407									molecular_function											owl:Class	
GO:0140680	biolink:NamedThing	histone H3-di/monomethyl-lysine-36 demethylase activity	Catalysis of the removal of a methyl group from a di- or a monomethyl-lysine residue at position 36 of the histone H3 protein. This is a dioxygenase reaction that is dependent on Fe(II) and 2-oxoglutarate.	tmpzr1t_l9r_go_relaxed.owl	histone H3K36me demethylase activity|histone H3K36me2 demethylase activity	https://github.com/geneontology/go-ontology/issues/21089			RHEA:42032|MetaCyc:RXN-8661|EC:1.14.11.27			pg	2021-07-08T14:12:22Z					molecular_function											owl:Class	
GO:0031749	biolink:NamedThing	D2 dopamine receptor binding	Binding to a D2 dopamine receptor.	tmpzr1t_l9r_go_relaxed.owl	D2 dopamine receptor ligand													molecular_function											owl:Class	
GO:0047723	biolink:NamedThing	inosinate nucleosidase activity	Catalysis of the reaction: H(2)O + IMP = D-ribose 5-phosphate + hypoxanthine.	tmpzr1t_l9r_go_relaxed.owl	5'-inosinate phosphoribohydrolase activity				RHEA:20469|EC:3.2.2.12|MetaCyc:INOSINATE-NUCLEOSIDASE-RXN|KEGG_REACTION:R01128									molecular_function											owl:Class	
GO:0047352	biolink:NamedThing	adenylylsulfate-ammonia adenylyltransferase activity	Catalysis of the reaction: 5'-adenylyl sulfate + NH(4)(+) = adenosine 5'-phosphoramidate + 2 H(+) + sulfate.	tmpzr1t_l9r_go_relaxed.owl	APSAT|adenylylsulfate:ammonia adenylyltransferase activity|adenylylsulphate-ammonia adenylyltransferase activity				RHEA:19197|EC:2.7.7.51|MetaCyc:2.7.7.51-RXN|KEGG_REACTION:R01619									molecular_function											owl:Class	
GO:0034554	biolink:NamedThing	3,3',5-tribromobisphenol A reductive dehalogenase activity	Catalysis of the reaction: 3,3',5-tribromobisphenol A + 2 H+ + 2 e- = 3,3'-dibromobisphenol A + HBr.	tmpzr1t_l9r_go_relaxed.owl					EC:1.97.1.-|UM-BBD_reactionID:r0842									molecular_function											owl:Class	
GO:0005025	biolink:NamedThing	transforming growth factor beta receptor activity, type I	Combining with a complex of transforming growth factor beta and a type II TGF-beta receptor to initiate a change in cell activity; upon binding, acts as a downstream transducer of TGF-beta signals.	tmpzr1t_l9r_go_relaxed.owl	transforming growth factor beta ligand binding to type I receptor|type I TGF-beta receptor activity|type I TGFbeta receptor activity|type I transforming growth factor beta receptor activity													molecular_function											owl:Class	
GO:0080119	biolink:NamedThing	ER body organization	A process that is carried out at the cellular level which results in the formation of ER (endoplasmic reticulum) body. ER body is a compartment found in plant cells that is derived from the ER. The structures have a characteristic shape and size (10 mm long and 0.5 mm wide) and are surrounded with ribosomes. They have been found in Arabidopsis thaliana and related Brassicaceae species.	tmpzr1t_l9r_go_relaxed.owl	ER body organization and biogenesis|endoplasmic reticulum body organization and biogenesis|endoplasmic reticulum body organization|ER body organisation							dhl	2009-04-27T04:01:26Z					biological_process											owl:Class	
GO:1990075	biolink:NamedThing	periciliary membrane compartment	A plasma membrane region adjacent to the base of eukaryotic cilia and flagella that is enriched in endocytosis-associated proteins and vesicles and that appears to regulate ciliary membrane homeostasis.	tmpzr1t_l9r_go_relaxed.owl	PCMC							pr	2013-04-24T10:14:50Z					cellular_component											owl:Class	
GO:0010790	biolink:NamedThing	meiotic sister chromatid cohesion involved in meiosis II	The cell cycle process in which sister chromatids of a replicated chromosome are joined along the entire length of the chromosome during meiosis II.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0018781	biolink:NamedThing	S-triazine hydrolase activity	Catalysis of the reaction: 1-halo or 1-pseudohalo-S-triazine = 1-hydroxy-S-triazine.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_enzymeID:e0091									molecular_function											owl:Class	
GO:0008660	biolink:NamedThing	1-aminocyclopropane-1-carboxylate deaminase activity	Catalysis of the reaction: 1-aminocyclopropane-1-carboxylate + H(2)O = 2-oxobutanate + NH(4)(+).	tmpzr1t_l9r_go_relaxed.owl	ACC deaminase activity|1-aminocyclopropane carboxylic acid deaminase activity|1-aminocyclopropane-1-carboxylate aminohydrolase (isomerizing)|1-aminocyclopropane-1-carboxylate endolyase (deaminating) activity				UM-BBD_reactionID:r0357|KEGG_REACTION:R00997|EC:3.5.99.7|MetaCyc:4.1.99.4-RXN|RHEA:16933	Note that this function was formerly EC:4.1.99.4.						GO:0018806		molecular_function											owl:Class	
GO:0050742	biolink:NamedThing	protein-FMN linkage via S-(4a-FMN)-L-cysteine	The formation of a protein-FMN linkage via S-(4a-FMN)-L-cysteine.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0351									biological_process											owl:Class	
GO:0102421	biolink:NamedThing	curcumin-4'-O-beta-D-gentiobioside 1,6-glucosyltransferase activity	Catalysis of the reaction: curcumin 4'-O-beta-D-gentiobioside + UDP-alpha-D-glucose <=> curcumin 4'-O-beta-D-gentiotrioside + UDP + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-13813									molecular_function											owl:Class	
GO:0036457	biolink:NamedThing	keratohyalin granule	A cytoplasmic, non-membrane bound granule of, at least, keratinocyte. Associated to keratin intermediate filaments and partially crosslinked to the cell envelope.	tmpzr1t_l9r_go_relaxed.owl								bf	2013-12-09T13:04:09Z					cellular_component											owl:Class	
GO:0120026	biolink:NamedThing	host cell uropod	A host cell membrane projection with related cytoskeletal components at the trailing edge of a cell in the process of migrating or being activated, found on the opposite side of the cell from the leading edge or immunological synapse, respectively.	tmpzr1t_l9r_go_relaxed.owl	host cell uropodium							krc	2017-03-22T21:33:31Z					cellular_component											owl:Class	
GO:0061481	biolink:NamedThing	response to TNF agonist	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a TNF agonist stimulus.	tmpzr1t_l9r_go_relaxed.owl								dph	2012-11-07T09:14:07Z					biological_process											owl:Class	
GO:1905217	biolink:NamedThing	response to astaxanthin	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an astaxanthin stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to (3S,3'S)-3,3'-dihydroxy-beta,beta-carotene-4,4'-dione							sl	2016-06-06T21:30:00Z					biological_process											owl:Class	
GO:0047427	biolink:NamedThing	cyanoalanine nitrilase activity	Catalysis of the reaction: 3-cyano-L-alanine + 2 H(2)O + H(+) = L-aspartate + NH(4)(+).	tmpzr1t_l9r_go_relaxed.owl	3-cyano-L-alanine aminohydrolase activity|beta-cyanoalanine nitrilase activity				RHEA:11188|EC:3.5.5.4|KEGG_REACTION:R00486|MetaCyc:3.5.5.4-RXN									molecular_function											owl:Class	
GO:0102081	biolink:NamedThing	homotaurine:2-oxoglutarate aminotransferase activity	Catalysis of the reaction: homotaurine + 2-oxoglutarate(2-) <=> 3-sulfopropanal + L-glutamate(1-).	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-10822									molecular_function											owl:Class	
GO:0016996	biolink:NamedThing	endo-alpha-(2,8)-sialidase activity	Catalysis of the endohydrolysis of (2->8)-alpha-sialosyl linkages in oligo- or poly(sialic) acids.	tmpzr1t_l9r_go_relaxed.owl	endoneuraminidase activity|alpha-2,8-sialosylhydrolase activity|endosialidase activity|polysialoside (2->8)-alpha-sialosylhydrolase activity|poly(alpha-2,8-sialoside) alpha-2,8-sialosylhydrolase activity|endo-N-acylneuraminidase activity|endo-N-acetylneuraminidase activity|poly(alpha-2,8-sialosyl) endo-N-acetylneuraminidase activity				EC:3.2.1.129|MetaCyc:3.2.1.129-RXN									molecular_function											owl:Class	
GO:0034818	biolink:NamedThing	ADD 9alpha-hydroxylase activity	Catalysis of the reaction: androsta-1,4-diene-3,17-dione + reduced ferredoxin + O2 = 3-hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione + H2O + oxidized ferredoxin.	tmpzr1t_l9r_go_relaxed.owl					EC:1.14.15.-|UM-BBD_reactionID:r1149									molecular_function											owl:Class	
GO:0034768	biolink:NamedThing	(E)-beta-ocimene synthase activity	Catalysis of the reaction: geranyl diphosphate = (E)-beta-ocimene + diphosphate.	tmpzr1t_l9r_go_relaxed.owl					RHEA:32691|EC:4.2.3.106|MetaCyc:RXN-5109									molecular_function											owl:Class	
GO:0008792	biolink:NamedThing	arginine decarboxylase activity	Catalysis of the reaction: L-arginine + H(+) = agmatine + CO(2).	tmpzr1t_l9r_go_relaxed.owl	L-arginine carboxy-lyase activity|SpeA|L-arginine carboxy-lyase (agmatine-forming)				MetaCyc:ARGDECARBOX-RXN|EC:4.1.1.19|KEGG_REACTION:R00566|RHEA:17641|Reactome:R-HSA-350598									molecular_function											owl:Class	
GO:0003117	biolink:NamedThing	regulation of vasoconstriction by circulating norepinephrine	Any process that modulates the frequency, rate or extent of reductions in the diameter of blood vessels as a result of secretion of norepinephrine into the bloodstream.	tmpzr1t_l9r_go_relaxed.owl	regulation of vasoconstriction by circulating noradrenaline													biological_process											owl:Class	
GO:0052899	biolink:NamedThing	N(1),N(12)-diacetylspermine:oxygen oxidoreductase (3-acetamidopropanal-forming) activity	Catalysis of the reaction: H(2)O + N(1),N(12)-diacetylspermine + O(2) = 3-acetamidopropanal + H(2)O(2) + N(1)-acetylspermidine.	tmpzr1t_l9r_go_relaxed.owl	polyamine oxidase activity|N(1)-acetylpolyamine oxidase activity				EC:1.5.3.13|RHEA:25868|MetaCyc:RXN-10460									molecular_function											owl:Class	
GO:0018401	biolink:NamedThing	peptidyl-proline hydroxylation to 4-hydroxy-L-proline	The modification of peptidyl-proline to form 4-hydroxy-L-proline; catalyzed by procollagen-proline,2-oxoglutarate-4-dioxygenase.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0030	See also the molecular function term 'procollagen-proline 4-dioxygenase activity ; GO:0004656'.								biological_process											owl:Class	
GO:0008123	biolink:NamedThing	cholesterol 7-alpha-monooxygenase activity	Catalysis of the reaction: cholesterol + NADPH + H+ + O2 = 7-alpha-hydroxycholesterol + NADP+ + H2O.	tmpzr1t_l9r_go_relaxed.owl	cholesterol 7-alpha-hydroxylase activity|cholesterol 7alpha-monooxygenase activity|cholesterol 7alpha-hydroxylase activity|cholesterol,NADPH:oxygen oxidoreductase (7alpha-hydroxylating)|cytochrome P450 CYP7A1				MetaCyc:CHOLESTEROL-7-ALPHA-MONOOXYGENASE-RXN|EC:1.14.14.23|Reactome:R-HSA-192051|RHEA:21812									molecular_function											owl:Class	
GO:0039564	biolink:NamedThing	suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of a JAK-STAT signal cascade in a host organism by reducing the activity of host STAT2 (signal transducer and activator of transcription 2).	tmpzr1t_l9r_go_relaxed.owl	inhibition by virus of host STAT2 activity|suppression by virus of host STAT2 activity|inhibition of host STAT2 by virus	https://github.com/geneontology/go-ontology/issues/21963						bf	2012-03-12T02:52:34Z					biological_process											owl:Class	
GO:0097371	biolink:NamedThing	MDM2/MDM4 family protein binding	Binding to a member of the MDM2/MDM4 protein family, comprising negative regulators of p53.	tmpzr1t_l9r_go_relaxed.owl								pr	2012-08-08T16:20:59Z					molecular_function											owl:Class	
GO:0055051	biolink:NamedThing	ATP-binding cassette (ABC) transporter complex, integrated substrate binding	A complex for the transport of metabolites out of the cell, consisting of 4 domains: two ATP-binding domains and two membrane spanning domains. In some cases, all 4 domains are contained on 1 polypeptide, while in others one ATP-binding domain and one membrane spanning domain are together on one polypeptide in what is called a half transporter. Two half-transporters come together to form a functional transporter. Transport of the substrate across the membrane is driven by the hydrolysis of ATP.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0003847	biolink:NamedThing	1-alkyl-2-acetylglycerophosphocholine esterase activity	Catalysis of the reaction: 2-acetyl-1-alkyl-sn-glycero-3-phosphocholine + H2O = 1-alkyl-sn-glycero-3-phosphocholine + acetate.	tmpzr1t_l9r_go_relaxed.owl	1-alkyl-2-acetyl-sn-glycero-3-phosphocholine acetylhydrolase activity|PAF acetylhydrolase activity|2-acetyl-1-alkylglycerophosphocholine esterase activity|1-alkyl-2-acetyl-sn-glycero-3-phosphocholine acetohydrolase activity|LDL-associated phospholipase A(2) activity|alkylacetyl-GPC:acetylhydrolase activity|LDL-PLA(2) activity|PAF 2-acylhydrolase activity|LDL-PLA2|platelet-activating factor acetylhydrolase activity|LDL-associated phospholipase A2				MetaCyc:3.1.1.47-RXN|RHEA:17777|EC:3.1.1.47|Reactome:R-HSA-8869206									molecular_function											owl:Class	
GO:0016024	biolink:NamedThing	CDP-diacylglycerol biosynthetic process	The chemical reactions and pathways resulting in the formation of CDP-diacylglycerol, CDP-1,2-diacylglycerol, a substance composed of diacylglycerol in glycosidic linkage with cytidine diphosphate.	tmpzr1t_l9r_go_relaxed.owl	CDP-diacylglycerol biosynthesis|CDP-diacylglycerol formation|CDP-diacylglycerol anabolism|CDP-diacylglycerol synthesis													biological_process											owl:Class	
GO:0042564	biolink:NamedThing	NLS-dependent protein nuclear import complex	A dimer consisting of an alpha and a beta-subunit that imports proteins with an NLS into the nucleus through a nuclear pore.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0097275	biolink:NamedThing	cellular ammonium homeostasis	Any biological process involved in the maintenance of an internal steady state of ammonium at the level of the cell.	tmpzr1t_l9r_go_relaxed.owl	cellular ammonia homeostasis							pr	2012-03-22T02:54:38Z					biological_process											owl:Class	
GO:0047242	biolink:NamedThing	hydroxyanthraquinone glucosyltransferase activity	Catalysis of the reaction: a hydroxyanthraquinone + UDP-D-glucose = a glucosyloxyanthraquinone + UDP.	tmpzr1t_l9r_go_relaxed.owl	UDPglucose:hydroxyanthraquinone O-glucosyltransferase activity|anthraquinone-specific glucosyltransferase activity|UDP-glucose:hydroxyanthraquinone O-glucosyltransferase activity|uridine diphosphoglucose-anthraquinone glucosyltransferase activity				MetaCyc:2.4.1.181-RXN|EC:2.4.1.181									molecular_function											owl:Class	
GO:0047701	biolink:NamedThing	beta-L-arabinosidase activity	Catalysis of the reaction: H2O + a beta-L-arabinoside = L-arabinose + an alcohol.	tmpzr1t_l9r_go_relaxed.owl	vicianosidase activity|beta-L-arabinoside arabinohydrolase activity|b-L-arabinosidase activity				MetaCyc:BETA-L-ARABINOSIDASE-RXN|EC:3.2.1.88									molecular_function											owl:Class	
GO:0009915	biolink:NamedThing	phloem sucrose loading	The process of loading sucrose into the sieve tube or companion cell of the phloem for long distance transport from source to sink.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0004648	biolink:NamedThing	O-phospho-L-serine:2-oxoglutarate aminotransferase activity	Catalysis of the reaction: O-phospho-L-serine + 2-oxoglutarate = 3-phosphonooxypyruvate + L-glutamate.	tmpzr1t_l9r_go_relaxed.owl	3-O-phospho-L-serine:2-oxoglutarate aminotransferase activity|PSAT activity|hydroxypyruvic phosphate--glutamic transaminase activity|SerC|L-phosphoserine aminotransferase activity|3PHP transaminase activity|PdxC|phosphohydroxypyruvate transaminase activity|3-phosphoserine aminotransferase activity|phosphoserine aminotransferase activity|phosphohydroxypyruvic--glutamic transaminase activity|phosphoserine transaminase activity				Reactome:R-HSA-977333|MetaCyc:PSERTRANSAM-RXN|EC:2.6.1.52|RHEA:14329							GO:0004646		molecular_function											owl:Class	
GO:0044689	biolink:NamedThing	7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase activity	Catalysis of the reaction: 5-amino-6-(D-ribitylamino)uracil + 4-hydroxyphenylpyruvate + 2 S-adenosyl-L-methionine + H2O = 7,8-didemethyl-8-hydroxy-5-deazariboflavin + 2 5'-deoxyadenosine + 2 L-methionine + oxalate + ammonia + 4 H+.	tmpzr1t_l9r_go_relaxed.owl	FO synthase				EC:2.5.1.147|MetaCyc:RXN-8079			jl	2012-08-15T14:33:17Z					molecular_function											owl:Class	
GO:0016852	biolink:NamedThing	sirohydrochlorin cobaltochelatase activity	Catalysis of the reaction: sirohydrochlorin + Co2+ = cobalt-sirohydrochlorin + 2 H+.	tmpzr1t_l9r_go_relaxed.owl	sirohydrochlorin cobalt-lyase activity|CbiX|cobalt-sirohydrochlorin cobalt-lyase (sirohydrochlorin-forming)|CbiK|anaerobic cobalt chelatase activity|CbiXS				MetaCyc:4.99.1.3-RXN|RHEA:15893|EC:4.99.1.3									molecular_function											owl:Class	
GO:0044540	biolink:NamedThing	L-cystine L-cysteine-lyase (deaminating)	Catalysis of the reaction: L-cystine + H2O <=> pyruvate + NH3 + thiocysteine. Thiocysteine is also known as cysteine persulfide.	tmpzr1t_l9r_go_relaxed.owl					KEGG_REACTION:R02408|RHEA:24927|EC:4.4.1.1			jl	2012-03-22T11:33:32Z					molecular_function											owl:Class	
GO:0001632	biolink:NamedThing	leukotriene B4 receptor activity	Combining with leukotriene B4, LTB4, to initiate a change in cell activity. Leukotriene B4 is also known as (6Z, 8E, 10E, 14Z)-(5S, 12R)-5,12-dihydroxyicosa-6,8,10,14-tetraen-1-oate.	tmpzr1t_l9r_go_relaxed.owl	BLT receptor													molecular_function											owl:Class	
GO:0000450	biolink:NamedThing	cleavage of bicistronic rRNA transcript (SSU-rRNA, LSU-rRNA)	Endonucleolytic cleavage of pre-rRNAs originally produced as a bicistronic rRNA transcript that contains the SSU-rRNA and the LSU-rRNA in that order from 5' to 3' along the primary transcript. Primary ribosomal RNA transcripts with two genes in this order are produced in Archaeal species.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0103069	biolink:NamedThing	17-hydroxyprogesterone 21-hydroxylase activity	Catalysis of the reaction: 17alpha-hydroxyprogesterone + O2 + reduced [NADPH--hemoprotein reductase] = 11-deoxycortisol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase].	tmpzr1t_l9r_go_relaxed.owl					RHEA:50308|MetaCyc:RXN66-356									molecular_function											owl:Class	
GO:0102918	biolink:NamedThing	(R)-reticuline 7-O-methyltransferase activity	Catalysis of the reaction: (R)-reticulinium(1+) + S-adenosyl-L-methionine  <=> (R)-laudanine(1+) + S-adenosyl-L-homocysteine  + H+.	tmpzr1t_l9r_go_relaxed.owl					RHEA:38907|EC:2.1.1.291|MetaCyc:RXN-8701									molecular_function											owl:Class	
GO:0050464	biolink:NamedThing	nitrate reductase (NADPH) activity	Catalysis of the reaction: nitrite + NADP+ + H2O = nitrate + NADPH + H+.	tmpzr1t_l9r_go_relaxed.owl	NADPH:nitrate reductase activity|assimilatory NADPH-nitrate reductase activity|NADPH-nitrate reductase activity|triphosphopyridine nucleotide-nitrate reductase activity|nitrate reductase (NADPH2)|nitrate reductase (NADPH(2)) activity|nitrite:NADP+ oxidoreductase activity|assimilatory nitrate reductase activity|NADPH:nitrate oxidoreductase activity|assimilatory reduced nicotinamide adenine dinucleotide phosphate-nitrate reductase activity				MetaCyc:NITRATE-REDUCTASE-NADPH-RXN|EC:1.7.1.3|RHEA:19061									molecular_function											owl:Class	
GO:0019836	biolink:NamedThing	hemolysis by symbiont of host erythrocytes	The cytolytic destruction of red blood cells, with the release of intracellular hemoglobin, in the host organism by a symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	haemolysis in host|pathogenesis|hemolysis by symbiont of host red blood cells|regulation of cytolysis of host cells by symbiont|hemolysis by symbiont of host RBCs|hemolysin activity													biological_process											owl:Class	
GO:0046703	biolink:NamedThing	natural killer cell lectin-like receptor binding	Binding to a lectin-like natural killer cell receptor.	tmpzr1t_l9r_go_relaxed.owl	KLRC4 receptor binding|NKG2D receptor binding|NK cell lectin-like receptor binding													molecular_function											owl:Class	
GO:0009344	biolink:NamedThing	nitrite reductase complex [NAD(P)H]	Complex that possesses nitrite reductase [NAD(P)H] activity.	tmpzr1t_l9r_go_relaxed.owl						See also the molecular function term 'nitrite reductase [NAD(P)H] activity ; GO:0008942'.								cellular_component											owl:Class	
GO:0102992	biolink:NamedThing	2-methylbutyronitrile hydroxylase activity	Catalysis of the reaction: H+ + 2-methylbutyronitrile + NADPH + O2 <=> H2O + NADP + 2-hydroxy-2-methylbutyronitrile.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-9642|RHEA:51948									molecular_function											owl:Class	
GO:0102267	biolink:NamedThing	tRNA-dihydrouridine20b synthase activity	Catalysis of the reaction: a 5,6-dihydrouracil20b in tRNA + NAD(P) <=> H+ + a uracil20b in tRNA + NAD(P)H.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-12476									molecular_function											owl:Class	
GO:0008579	biolink:NamedThing	JUN kinase phosphatase activity	Catalysis of the reaction: JUN kinase serine/threonine/tyrosine phosphate + H2O = JUN kinase serine/threonine/tyrosine + phosphate.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0000933	biolink:NamedThing	adventitious septum	A cell septum whose formation is independent of nuclear division.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0102514	biolink:NamedThing	cyanidin 3-O-glucoside 7-O-glucosyltransferase (feruloyl-glucose dependent) activity	Catalysis of the reaction: cyanidin 3-O-beta-D-glucoside betaine + 1-O-feruloyl-beta-D-glucose <=> cyanidin 3,7-di-O-beta-D-glucoside betaine + ferulate + H+.	tmpzr1t_l9r_go_relaxed.owl					EC:2.4.1.300|MetaCyc:RXN-14446									molecular_function											owl:Class	
GO:0034570	biolink:NamedThing	hydroxymonomethylisoproturon dimethylaminedehydrogenase activity	Catalysis of the reaction: hydroxymonodemethylisoproturon + H2O = formaldehyde + 4'-(2-hydroxyisopropyl)phenylurea + 2 H+ + 2 e-.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0894|EC:1.5.99.-									molecular_function											owl:Class	
GO:1990358	biolink:NamedThing	xylanosome	A multifunctional supermolecular complex, containing several proteins with hemicellulase activity. Functions to hydrolyze hemicellulose.	tmpzr1t_l9r_go_relaxed.owl	xylanolytic complex							tt	2014-04-05T18:08:54Z					cellular_component											owl:Class	
GO:0030848	biolink:NamedThing	threo-3-hydroxyaspartate ammonia-lyase activity	Catalysis of the reaction: (3S)-3-hydroxy-L-aspartate = NH(4)(+) + oxaloacetate.	tmpzr1t_l9r_go_relaxed.owl	L-threo-3-hydroxyaspartate dehydratase activity|threo-3-hydroxy-L-aspartate ammonia-lyase (oxaloacetate-forming)|3-hydroxyaspartate dehydratase activity|threo-3-hydroxy-L-aspartate ammonia-lyase activity|threo-3-hydroxyaspartate dehydratase activity				KEGG_REACTION:R05758|MetaCyc:4.3.1.16-RXN|RHEA:12424|EC:4.3.1.16									molecular_function											owl:Class	
GO:0102711	biolink:NamedThing	gibberellin A25,oxoglutarate:oxygen oxidoreductase activity	Catalysis of the reaction: gibberellin A25 + 2-oxoglutarate + O2 <=> gibberellin A13 + succinate + carbon dioxide.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-6541									molecular_function											owl:Class	
GO:0038173	biolink:NamedThing	interleukin-17A-mediated signaling pathway	A series of molecular signals initiated by the binding of interleukin-17A to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.	tmpzr1t_l9r_go_relaxed.owl	interleukin-17A signaling pathway|interleukin-17A-mediated signalling pathway|IL17A signaling pathway|IL-17A-mediated signaling pathway							bf	2012-06-12T10:59:01Z					biological_process											owl:Class	
GO:0102801	biolink:NamedThing	anthocyanin 5-O-glucoside-4'''-O-malonyltransferase activity	Catalysis of the reaction: 4'''-demalonylsalvianin + malonyl-CoA = salvianin + coenzyme A.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-8139|EC:2.3.1.214|RHEA:35515									molecular_function											owl:Class	
GO:0090430	biolink:NamedThing	caffeoyl-CoA: alcohol caffeoyl transferase activity	Catalysis of the reaction: caffeoyl-CoA + a saturated primary alcohol = an alkyl caffeate + CoA.	tmpzr1t_l9r_go_relaxed.owl								tb	2012-07-25T10:48:15Z					molecular_function											owl:Class	
GO:0008430	biolink:NamedThing	selenium binding	Binding to a selenium (Se) ion.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0047641	biolink:NamedThing	aldose-6-phosphate reductase (NADPH) activity	Catalysis of the reaction: D-glucitol 6-phosphate + NADP(+) = D-glucose 6-phosphate + H(+) + NADPH.	tmpzr1t_l9r_go_relaxed.owl	NADP-dependent D-sorbitol-6-phosphate dehydrogenase activity|alditol 6-phosphate:NADP 1-oxidoreductase activity|aldose 6-phosphate reductase activity|D-aldose-6-phosphate:NADP+ 1-oxidoreductase activity|NADP-dependent aldose 6-phosphate reductase activity|aldose-6-P reductase activity|A6PR|aldose-6-phosphate reductase activity				MetaCyc:ALDOSE-6-PHOSPHATE-REDUCTASE-NADPH-RXN|RHEA:20037|EC:1.1.1.200|KEGG_REACTION:R00834									molecular_function											owl:Class	
GO:0030109	biolink:NamedThing	HLA-B specific inhibitory MHC class I receptor activity	Combining with a MHC class I molecule of the HLA-B subclass to mediate signaling that inhibits activation of a lymphocyte.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0008254	biolink:NamedThing	3'-nucleotidase activity	Catalysis of the reaction: a 3'-ribonucleotide + H2O = a ribonucleoside + phosphate.	tmpzr1t_l9r_go_relaxed.owl	3'-ribonucleotide phosphohydrolase activity|3'-phosphatase activity|3'-ribonucleotidase activity|3' nucleotidase activity|3'-mononucleotidase activity				EC:3.1.3.6|RHEA:10144|MetaCyc:3-NUCLEOTID-RXN									molecular_function											owl:Class	
GO:0102875	biolink:NamedThing	1-18:2-2-18:2-monogalactosyldiacylglycerol desaturase activity	Catalysis of the reaction: 1-18:2-2-18:2-monogalactosyldiacylglycerol + O2 + a reduced electron acceptor <=> 1-18:3-2-18:2-monogalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-8366|EC:1.14.19.35									molecular_function											owl:Class	
GO:0030791	biolink:NamedThing	arsenite methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + arsenite = S-adenosyl-L-homocysteine + methylarsonate.	tmpzr1t_l9r_go_relaxed.owl	S-adenosyl-L-methionine:methylarsonite As-methyltransferase activity|S-adenosyl-L-methionine:arsenite As-methyltransferase activity|S-adenosyl-L-methionine:arsenic(III) methyltransferase activity				Reactome:R-HSA-5696213|RHEA:15293|MetaCyc:2.1.1.137-RXN|Reactome:R-HSA-5696220|UM-BBD_reactionID:r0805|EC:2.1.1.137	Note that the enzyme arsenite methyltransferase also has methylarsonite methyltransferase activity (GO:0030792).								molecular_function											owl:Class	
GO:0044739	biolink:NamedThing	positive regulation of acid-sensing ion channel in other organism	Any process in which an organism positively regulates the activity of a voltage-gated sodium channel in another organism.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of ASIC channel in other organism							jl	2012-11-06T16:56:27Z					biological_process											owl:Class	
GO:0070702	biolink:NamedThing	inner mucus layer	The inner of two mucus layers secreted by epithelial cells in the colon; the inner mucus layer is firmly attached to the epithelium, is densely packed with a compact stratified appearance and is devoid of bacteria.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-06-08T02:38:55Z					cellular_component											owl:Class	
GO:0102122	biolink:NamedThing	gibberellin A34 carboxyl methyltransferase activity	Catalysis of the reaction: gibberellin A34 + S-adenosyl-L-methionine  = gibberellin A34 methyl ester + S-adenosyl-L-homocysteine.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-11384|RHEA:36127									molecular_function											owl:Class	
GO:1901169	biolink:NamedThing	3-chlorocatechol biosynthetic process	The chemical reactions and pathways resulting in the formation of 3-chlorocatechol.	tmpzr1t_l9r_go_relaxed.owl	3-chlorocatechol synthesis|3-chlorocatechol formation|3-chlorocatechol anabolism|3-chlorocatechol biosynthesis							yaf	2012-07-19T09:33:45Z					biological_process											owl:Class	
GO:0072645	biolink:NamedThing	interferon-delta production	The appearance of interferon-delta due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	tmpzr1t_l9r_go_relaxed.owl	IFN-delta production|IFND production|interferon-delta secretion					Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.						GO:0072646		biological_process											owl:Class	
GO:0034908	biolink:NamedThing	2-chloro-N-isopropylacetanilide 1,2-dioxygenase activity	Catalysis of the reaction: 2-chloro-N-isopropylacetanilide + O2 + 2 H+ + NADH = 2-chloro-N-isopropylacetamide + catechol + NAD+.	tmpzr1t_l9r_go_relaxed.owl					EC:1.14.12.-|UM-BBD_reactionID:r0724									molecular_function											owl:Class	
GO:0033698	biolink:NamedThing	Rpd3L complex	A histone deacetylase complex which deacetylates histones preferentially in promoter regions. Composed of a catalytic histone deacetylase subunit, an Sds-3 family protein, a SIN3 family co-repressor, a WD repeat protein, and a zf- PHD finger (Clr6, Sds3, Pst1, Prw1, Png2 in Schizosaccharomyces pombe; Rpd3p, Sin3p, Ume1p, Pho23p, Sap30p, Sds3p, Cti6p, Rxt2p, Rxt3p, Dep1p, Ume6p and Ash1p in Saccharomyces cerevisiae).	tmpzr1t_l9r_go_relaxed.owl	Rpd3C(L)|Clr6 histone deacetylase complex I/I'|Clr6L complex											GO:0000508		cellular_component											owl:Class	
GO:0070388	biolink:NamedThing	procollagen-proline 4-dioxygenase complex, alpha(III) type	A procollagen-proline 4-dioxygenase complex that contains alpha subunits of the type III isoform.	tmpzr1t_l9r_go_relaxed.owl	prolyl 4-hydroxylase complex (alpha(III)-type)|procollagen-proline, 2-oxoglutarate-4-dioxygenase complex, alpha(III) type													cellular_component											owl:Class	
GO:0047990	biolink:NamedThing	hydroxyglutamate decarboxylase activity	Catalysis of the reaction: 3-hydroxy-L-glutamate + H(+) = 4-amino-3-hydroxybutanoate + CO(2).	tmpzr1t_l9r_go_relaxed.owl	3-hydroxy-L-glutamate 1-carboxy-lyase (4-amino-3-hydroxybutanoate-forming)|3-hydroxy-L-glutamate 1-carboxy-lyase activity				KEGG_REACTION:R04135|RHEA:14073|MetaCyc:HYDROXYGLUTAMATE-DECARBOXYLASE-RXN|EC:4.1.1.16									molecular_function											owl:Class	
GO:0106329	biolink:NamedThing	L-phenylalaine oxidase activity	Catalysis of the reaction: H2O + L-phenylalanine + O2 = 3-phenylpyruvate + H2O2 + NH4(+).	tmpzr1t_l9r_go_relaxed.owl					RHEA:61240			hjd	2020-09-30T19:33:52Z					molecular_function											owl:Class	
GO:0047033	biolink:NamedThing	15-hydroxyprostaglandin-I dehydrogenase (NADP+) activity	Catalysis of the reaction: NADP(+) + prostaglandin I(2) = 15-dehydro-prostaglandin I(2) + H(+) + NADPH.	tmpzr1t_l9r_go_relaxed.owl	(5Z,13E)-(15S)-6,9alpha-epoxy-11alpha,15-dihydroxyprosta-5,13-dienoate:NADP+ 15-oxidoreductase activity|prostacyclin dehydrogenase activity|NADP+-dependent PGI2-specific 15-hydroxyprostaglandin dehydrogenase activity|NADP-linked 15-hydroxyprostaglandin (prostacyclin) dehydrogenase activity|PG I2 dehydrogenase activity				MetaCyc:1.1.1.231-RXN|KEGG_REACTION:R03520|RHEA:21420|EC:1.1.1.231									molecular_function											owl:Class	
GO:0097074	biolink:NamedThing	interferon regulatory factor 7 complex	An interferon regulatory factor complex that consists of a homodimer of interferon regulatory factor 7.	tmpzr1t_l9r_go_relaxed.owl	IRF7:IRF7 complex							pr	2011-06-15T04:31:04Z					cellular_component											owl:Class	
GO:0097657	biolink:NamedThing	3',5'-nucleotide bisphosphate phosphatase activity	Catalysis of the reaction: 3',5'-nucleoside bisphosphate + H20 = 5'-nucleoside monophosphate + phosphate.	tmpzr1t_l9r_go_relaxed.owl					RHEA:43532|EC:3.1.3.97			pr	2014-09-25T11:21:39Z					molecular_function											owl:Class	
GO:0047445	biolink:NamedThing	3-hydroxy-3-isohexenylglutaryl-CoA lyase activity	Catalysis of the reaction: 3-hydroxy-3-(4-methylpent-3-en-1-yl)glutaryl-CoA + 4 H(+) = 7-methyl-3-oxooct-6-enoyl-CoA + acetate.	tmpzr1t_l9r_go_relaxed.owl	3-hydroxy-3-(4-methylpent-3-en-1-yl)glutaryl-CoA acetate-lyase activity|hydroxyisohexenylglutaryl-CoA:acetatelyase activity|3-hydroxy-3-isohexenylglutaryl coenzyme A lyase activity|3-hydroxy-3-(4-methylpent-3-en-1-yl)glutaryl-CoA acetate-lyase (7-methyl-3-oxooct-6-enoyl-CoA-forming)|3-hydroxy-3-isohexenylglutaryl-CoA isopentenylacetoacetyl-CoA-lyase activity|beta-hydroxy-beta-isohexenylglutaryl CoA-lyase activity				KEGG_REACTION:R08090|UM-BBD_reactionID:r1168|RHEA:23084|MetaCyc:4.1.3.26-RXN|EC:4.1.3.26									molecular_function											owl:Class	
GO:0004083	biolink:NamedThing	bisphosphoglycerate 2-phosphatase activity	Catalysis of the reaction: 2,3-bisphospho-D-glycerate + H(2)O = 3-phospho-D-glycerate + phosphate.	tmpzr1t_l9r_go_relaxed.owl	2,3-bisphospho-D-glycerate 2-phosphohydrolase activity				KEGG_REACTION:R01516|RHEA:21904|MetaCyc:BISPHOSPHOGLYCERATE-PHOSPHATASE-RXN									molecular_function											owl:Class	
GO:0103009	biolink:NamedThing	3-chlorotoluene monooxygenase activity	Catalysis of the reaction: H+ + 3-chlorotoluene + NADH + O2 <=> 3-chlorobenzyl alcohol + NAD + H2O.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-9908									molecular_function											owl:Class	
GO:0085039	biolink:NamedThing	hyphal membrane	A host-derived membrane surrounding the symbiont hypha during infection.	tmpzr1t_l9r_go_relaxed.owl	extra-invasive hyphal membrane	https://github.com/geneontology/go-ontology/issues/19013						jl	2010-07-27T04:19:46Z					cellular_component											owl:Class	
GO:1990327	biolink:NamedThing	collagen type XXV trimer	A collagen homotrimer of alpha1(XXV) chains; type XXV collagen triple helices span the plasma membrane.	tmpzr1t_l9r_go_relaxed.owl								bhm	2014-03-17T09:28:50Z					cellular_component											owl:Class	
GO:0004797	biolink:NamedThing	thymidine kinase activity	Catalysis of the reaction: ATP + thymidine = ADP + thymidine 5'-phosphate.	tmpzr1t_l9r_go_relaxed.owl	deoxythymidine kinase (phosphorylating)|2'-deoxythymidine kinase activity|ATP:thymidine 5'-phosphotransferase activity|thymidine kinase (phosphorylating)				MetaCyc:THYKI-RXN|EC:2.7.1.21|RHEA:19129									molecular_function											owl:Class	
GO:0008257	biolink:NamedThing	protein histidine tele-kinase activity	Catalysis of the reaction: ATP + protein L-histidine = ADP + protein N(tau)-phospho-L-histidine.	tmpzr1t_l9r_go_relaxed.owl	protein-histidine tele-kinase activity|HK3|ATP:protein-L-histidine N-tele-phosphotransferase activity|ATP:protein-L-histidine Ntau-phosphotransferase activity				MetaCyc:2.7.13.2-RXN|RHEA:11860|EC:2.7.13.2									molecular_function											owl:Class	
GO:0080074	biolink:NamedThing	spermidine:caffeoyl CoA N-acyltransferase activity	Catalysis of the transfer of a caffeoyl group to a nitrogen atom on the spermidine molecule.	tmpzr1t_l9r_go_relaxed.owl								dhl	2009-04-13T04:17:23Z					molecular_function											owl:Class	
GO:0106377	biolink:NamedThing	2-hydroxy-ATP hydrolase activity	Catalysis of the reaction: 2-hydroxy-ATP + H2O = 2-hydroxy-AMP + diphosphate.	tmpzr1t_l9r_go_relaxed.owl								hjd	2021-04-23T00:12:31Z					molecular_function											owl:Class	
GO:0044609	biolink:NamedThing	DBIRD complex	A protein complex that associates with mRNP particles and RNA polymerase II and is proposed to integrate transcript elongation with the regulation of alternative splicing. In humans it is composed of the proteins KIAA1967/DBC1 and ZNF326/ZIRD.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-05-30T03:04:23Z					cellular_component											owl:Class	
GO:0102924	biolink:NamedThing	gibberellin A44,2-oxoglutarate:oxygen oxidoreductase activity	Catalysis of the reaction: 2 H+ + gibberellin A44 + 2-oxoglutarate + O2 = gibberellin A98 + succinate + carbon dioxide.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-886									molecular_function											owl:Class	
GO:0051939	biolink:NamedThing	gamma-aminobutyric acid import	The directed movement of gamma-aminobutyric acid (GABA, 4-aminobutyrate) into a cell or organelle.	tmpzr1t_l9r_go_relaxed.owl	gamma-aminobutyrate import|4-aminobutyrate import|gamma-aminobutyric acid uptake|GABA import													biological_process											owl:Class	
GO:0070765	biolink:NamedThing	gamma-secretase complex	A protein complex that has aspartic-type endopeptidase activity and contains a presenilin catalytic subunit (either PSEN1 or PSEN2), an APH1 subunit (multiple genes and splice variants exist), nicastrin (NCT), and presenilin enhancer (aka PEN-2 or Psenen), as the core complex. Variants of the complex with different subunit compositions differ in localization and specific substrates. Additionally, variants of the complex exist that contain a additional regulatory subunit as well as the four core subunits; known regulatory subunits include gamma-secretase-activating protein (aka gSAP), TMP1 (aka TMED10), and CD147 antigen (aka basigin). Gamma-secretase cleaves type I transmembrane protein substrates, including the cell surface receptor Notch and the amyloid-beta precursor protein.	tmpzr1t_l9r_go_relaxed.owl	presenilin complex|PS2 complex|PS1 complex|gamma-secretase complex (APH1B, PSEN2, PSENEN, NCSTN)|gamma-secretase complex (APH1A, PSEN1, PSENEN, NCSTN variant)|CD147-gamma-secretase complex (APH-1a, PS-1, PEN-2, NCT variant)|gamma-secretase complex (APH1B, PSEN1, PSENEN, NCSTN)|gamma-secretase complex (APH1A, PSEN2, PSENEN, NCSTN)	https://github.com/geneontology/go-ontology/issues/20317						mah	2009-06-29T01:33:19Z					cellular_component											owl:Class	
GO:0015492	biolink:NamedThing	phenylalanine:proton symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: phenylalanine(out) + H+(out) = phenylalanine(in) + H+(in).	tmpzr1t_l9r_go_relaxed.owl	phenylalanine:hydrogen symporter activity													molecular_function											owl:Class	
GO:0009955	biolink:NamedThing	adaxial/abaxial pattern specification	The regionalization process in which differences in cell differentiation along the adaxial/abaxial are generated. Adaxial refers to being situated toward an axis of an anatomical structure. Abaxial refers to being situated away from an axis of an anatomical structure.	tmpzr1t_l9r_go_relaxed.owl	adaxial/abaxial pattern formation													biological_process											owl:Class	
GO:0004037	biolink:NamedThing	allantoicase activity	Catalysis of the reaction: allantoate + H(2)O = (S)-ureidoglycolate + urea.	tmpzr1t_l9r_go_relaxed.owl	allantoate amidinohydrolase activity|allantoine amidinohydrolase activity				MetaCyc:ALLANTOICASE-RXN|RHEA:11016|EC:3.5.3.4|KEGG_REACTION:R02422									molecular_function											owl:Class	
GO:0052596	biolink:NamedThing	phenethylamine:oxygen oxidoreductase (deaminating) activity	Catalysis of the reaction: phenylethylamine + O2 + H2O = phenylacetaldehyde + NH3 + hydrogen peroxide + H+.	tmpzr1t_l9r_go_relaxed.owl					KEGG_REACTION:R02613|MetaCyc:AMINEPHEN-RXN|RHEA:25265|EC:1.4.3.21									molecular_function											owl:Class	
GO:0097301	biolink:NamedThing	regulation of potassium ion concentration by positive regulation of transcription from RNA polymerase II promoter	Any process that regulates the internal concentration of potassium ions at the level of a cell by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter.	tmpzr1t_l9r_go_relaxed.owl	potassium ion homeostasis by positive regulation of transcription from RNA polymerase II promoter|cellular potassium ion homeostasis by positive regulation of transcription from RNA polymerase II promoter							pr	2012-05-09T09:03:02Z					biological_process											owl:Class	
GO:0007161	biolink:NamedThing	calcium-independent cell-matrix adhesion	The binding of a cell to the extracellular matrix via adhesion molecules that do not require the presence of calcium for the interaction.	tmpzr1t_l9r_go_relaxed.owl	calcium-independent cell adhesion molecule activity													biological_process											owl:Class	
GO:0062150	biolink:NamedThing	amorpha-4,11-diene 12-monooxygenase activity	Catalysis of the reaction:(+)-amorpha-4,11-diene + 3 O2 + 3 reduced [NADPH--hemoprotein reductase] = (+)-artemisinate + 4 H(+) + 4 H2O + 3 oxidized [NADPH--hemoprotein reductase].	tmpzr1t_l9r_go_relaxed.owl					EC:1.14.14.114|RHEA:32999			dph	2019-09-13T14:48:12Z					molecular_function											owl:Class	
GO:0005185	biolink:NamedThing	neurohypophyseal hormone activity	The action characteristic of a neurohypophyseal hormone, any of a family of structurally and functionally related nonapeptides that are synthesized as part of a larger precursor molecule comprising a signal peptide, the nonapeptide hormone, and a neurophysin.	tmpzr1t_l9r_go_relaxed.owl	neurohypophysial hormone activity													molecular_function											owl:Class	
GO:0018485	biolink:NamedThing	salicylaldehyde dehydrogenase activity	Catalysis of the reaction: salicylaldehyde + NAD+ + H2O = salicylate + NADH + H+.	tmpzr1t_l9r_go_relaxed.owl	salicylaldehyde:NAD+ oxidoreductase activity				MetaCyc:1.2.1.65-RXN|EC:1.2.1.65|UM-BBD_enzymeID:e0256|RHEA:18537									molecular_function											owl:Class	
GO:0034428	biolink:NamedThing	nuclear-transcribed mRNA catabolic process, exonucleolytic, 5'-3'	The chemical reactions and pathways resulting in the breakdown of the mRNA transcript body that occurs when the 5' end is not protected by a 5'-cap; degradation proceeds in the 5' to 3' direction.	tmpzr1t_l9r_go_relaxed.owl	5'-3' exonucleolytic nuclear-transcribed mRNA catabolic process													biological_process											owl:Class	
GO:0039552	biolink:NamedThing	RIG-I binding	Binding to RIG-I, a cytosolic pattern recognition receptor that initiates an antiviral signaling pathway upon binding to viral RNA.	tmpzr1t_l9r_go_relaxed.owl	DDX58/RIG-I binding|DDX58 binding							bf	2012-01-19T02:14:20Z					molecular_function											owl:Class	
GO:0097682	biolink:NamedThing	intracellular phosphatidylinositol-3,5-bisphosphate-sensitive cation channel activity	Enables the transmembrane transfer of cations by a channel that opens when phosphatidylinositol-3,5-bisphosphate has been bound by the channel complex or one of its constituent parts.	tmpzr1t_l9r_go_relaxed.owl								pr	2014-12-17T16:50:30Z					molecular_function											owl:Class	
GO:0050127	biolink:NamedThing	N-carbamoylsarcosine amidase activity	Catalysis of the reaction: N-carbamoylsarcosine + H(2)O + 2 H(+) = CO(2) + NH(4)(+) + sarcosine.	tmpzr1t_l9r_go_relaxed.owl	N-carbamoylsarcosine amidohydrolase activity|carbamoylsarcosine amidase activity|CSHase activity				KEGG_REACTION:R01563|EC:3.5.1.59|RHEA:20057|MetaCyc:N-CARBAMOYLSARCOSINE-AMIDASE-RXN									molecular_function											owl:Class	
GO:0047017	biolink:NamedThing	prostaglandin-F synthase activity	Catalysis of the reaction: NADP+ + (5Z,13E)-(15S)-9-alpha,11-alpha,15-trihydroxyprosta-5,13-dienoate = NADPH + H+ + (5Z,13E)-(15S)-9-alpha,15-dihydroxy-11-oxoprosta-5,13-dienoate.	tmpzr1t_l9r_go_relaxed.owl	prostaglandin-D(2) ketoreductase activity|prostaglandin F synthase activity|prostaglandin-D2 ketoreductase activity|PGD(2) 11-ketoreductase activity|prostaglandin-D(2) 11-reductase activity|prostaglandin D2-ketoreductase activity|(5Z,13E)-(15S)-9alpha,11alpha,15-trihydroxyprosta-5,13-dienoate:NADP+ 11-oxidoreductase activity|prostaglandin-D2 11-ketoreductase activity|PGF synthetase activity|prostaglandin 11-ketoreductase activity|prostaglandin-D2 11-reductase activity|reductase, 15-hydroxy-11-oxoprostaglandin|prostaglandin 11-keto reductase activity|PGD2 11-ketoreductase activity|PGF2alpha synthetase activity|prostaglandin F synthetase activity|prostaglandin-D(2) 11-ketoreductase activity|NADPH-dependent prostaglandin D2 11-keto reductase activity|synthetase, prostaglandin F2alpha|prostaglandin-F synthetase activity				MetaCyc:1.1.1.188-RXN|RHEA:10140|EC:1.1.1.188									molecular_function											owl:Class	
GO:0061070	biolink:NamedThing	female urethra development	The progression of the female urethra over time from its initial formation to the mature structure. The female urethra is a renal system organ that carries urine from the bladder to outside the body, exiting above the vaginal opening.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-03-12T08:29:43Z					biological_process											owl:Class	
GO:0052759	biolink:NamedThing	coenzyme F420-dependent 2,4,6-trinitrophenol hydride reductase activity	Catalysis of the reaction: trinitrophenol hydride Meisenheimer complex + H- = trinitrophenol dihydride Meisenheimer complex (aci form). Coenzyme F420 supplies the hydride (H-) in the reaction.	tmpzr1t_l9r_go_relaxed.owl	coenzyme F420-dependent 2,4,6-trinitrophenol-hydride-Meisenheimer-complex hydride transferase activity				UM-BBD_reactionID:r1066|EC:1.3.99.-				2011-09-28T01:50:17Z					molecular_function											owl:Class	
GO:0031467	biolink:NamedThing	Cul7-RING ubiquitin ligase complex	A ubiquitin ligase complex in which a cullin from the Cul7 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by a Skp1 linker and an F-box protein.	tmpzr1t_l9r_go_relaxed.owl	SCF7 complex|CRL7 complex|cullin-RING ligase 7|CDL7 complex													cellular_component											owl:Class	
GO:0102113	biolink:NamedThing	hypoxia-inducible factor-asparagine oxygenase activity	Catalysis of the reaction: 2-oxoglutarate + O2 + a hypoxia inducible factor (HIF) alpha subunit = succinate + carbon dioxide + a (3S)-3-hydroxy-L-asparagine-HIF alpha subunit.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-11321|RHEA:54268|EC:1.14.11.30									molecular_function											owl:Class	
GO:0019672	biolink:NamedThing	ethanol-acetate fermentation to butyrate and caproate	The anaerobic chemical reactions and pathways resulting in the breakdown of ethanol and acetate to butyrate and caproate, yielding energy in the form of ATP.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0044876	biolink:NamedThing	hercynylselenocysteine synthase	Catalysis of the reaction: 2 L-selenocysteine + 2 hercynine + O2 <=> 2 H2O + 2 hercynylselenocysteine.	tmpzr1t_l9r_go_relaxed.owl					RHEA:42680|MetaCyc:RXN-15803			jl	2014-12-15T11:56:12Z					molecular_function											owl:Class	
GO:0031695	biolink:NamedThing	alpha-2B adrenergic receptor binding	Binding to an alpha-2B adrenergic receptor.	tmpzr1t_l9r_go_relaxed.owl	alpha-2B adrenergic receptor ligand													molecular_function											owl:Class	
GO:0044227	biolink:NamedThing	methane-oxidizing organelle	A cytoplasmic, membrane-bounded compartment found within Methanotrophic bacteria that contains enzymes and electron transfer proteins for methane catabolism. This structure is analogous to the thylakoid of Cyanobacteria and the anammoxosome of anaerobic ammonium oxidation organisms.	tmpzr1t_l9r_go_relaxed.owl	methanotroph intracytoplasmic membrane-bound compartment|methane-oxidizing compartment							jl	2009-11-17T02:13:52Z					cellular_component											owl:Class	
GO:0071228	biolink:NamedThing	cellular response to tumor cell	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a tumor cell.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-12-03T02:04:43Z					biological_process											owl:Class	
GO:0102515	biolink:NamedThing	pelargonidin 3-O-glucoside 7-O-glucosyltransferase (feruloyl-glucose dependent) activity	Catalysis of the reaction: pelargonidin 3-O-beta-D-glucoside + 1-O-feruloyl-beta-D-glucose <=> pelargonidin 3,7-di-O-beta-D-glucoside + ferulate + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-14447									molecular_function											owl:Class	
GO:0047443	biolink:NamedThing	4-hydroxy-4-methyl-2-oxoglutarate aldolase activity	Catalysis of the reaction: 4-hydroxy-4-methyl-2-oxoglutarate = 2 pyruvate.	tmpzr1t_l9r_go_relaxed.owl	4-hydroxy-4-methyl-2-oxoglutarate pyruvate-lyase (pyruvate-forming)|4-hydroxy-4-methyl-2-ketoglutarate aldolase activity|pyruvate aldolase activity|gamma-methyl-gamma-hydroxy-alpha-ketoglutaric aldolase activity|4-hydroxy-4-methyl-2-oxoglutarate pyruvate-lyase activity				MetaCyc:4.1.3.17-RXN|EC:4.1.3.17|RHEA:22748									molecular_function											owl:Class	
GO:0010597	biolink:NamedThing	green leaf volatile biosynthetic process	The chemical reactions and pathways resulting in the formation of volatile molecules emitted from green plants, such as hexenal, hexenol and hexenyl acetate, from linoleic acid or linolenic acid.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0030059	biolink:NamedThing	aralkylamine dehydrogenase (azurin) activity	Catalysis of the reaction: an aralkylamine + H2O + 2 oxidized [azurin] = an aromatic aldehyde + 2 H+ + NH4+ + 2 reduced [azurin].	tmpzr1t_l9r_go_relaxed.owl	aralkylamine:(azurin) oxidoreductase (deaminating) activity|aromatic amine dehydrogenase (azurin) activity				RHEA:47796|EC:1.4.9.2|MetaCyc:ARALKYLAMINE-DEHYDROGENASE-RXN									molecular_function											owl:Class	
GO:0050681	biolink:NamedThing	androgen receptor binding	Binding to an androgen receptor.	tmpzr1t_l9r_go_relaxed.owl	AR binding													molecular_function											owl:Class	
GO:0102442	biolink:NamedThing	syringetin 3-O-methyltransferase activity	Catalysis of the reaction: syringetin(1-) + S-adenosyl-L-methionine  <=> 3,3',5'-trimethylmyricetin + S-adenosyl-L-homocysteine.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-13920									molecular_function											owl:Class	
GO:0030348	biolink:NamedThing	syntaxin-3 binding	Binding to a syntaxin-3 SNAP receptor.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0019905	biolink:NamedThing	syntaxin binding	Binding to a syntaxin, a SNAP receptor involved in the docking of synaptic vesicles at the presynaptic zone of a synapse.	tmpzr1t_l9r_go_relaxed.owl	syntaxin-5 binding|syntaxin-6 binding|syntaxin-2 binding|syntaxin-13 binding											GO:0050430|GO:0030347|GO:0051535|GO:0030349		molecular_function											owl:Class	
GO:2001072	biolink:NamedThing	galactomannan binding	Binding to galactomannan.	tmpzr1t_l9r_go_relaxed.owl								jl	2011-09-14T12:12:02Z					molecular_function											owl:Class	
GO:0102295	biolink:NamedThing	4-methylumbelliferyl glucoside 6'-O-malonyltransferase activity	Catalysis of the reaction: 4-methylumbelliferyl glucoside + malonyl-CoA <=> 4-methylumbelliferone 6'-O-malonylglucoside + coenzyme A.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-12699									molecular_function											owl:Class	
GO:0008774	biolink:NamedThing	acetaldehyde dehydrogenase (acetylating) activity	Catalysis of the reaction: acetaldehyde + CoA + NAD+ = acetyl-CoA + NADH + H+.	tmpzr1t_l9r_go_relaxed.owl	ADA|DmpF|aldehyde dehydrogenase (acylating) activity|acylating acetaldehyde dehydrogenase activity|acetaldehyde:NAD+ oxidoreductase (CoA-acetylating)				RHEA:23288|MetaCyc:ACETALD-DEHYDROG-RXN|EC:1.2.1.10									molecular_function											owl:Class	
GO:0055056	biolink:NamedThing	D-glucose transmembrane transporter activity	Enables the transfer of the D-enantiomer of the hexose monosaccharide glucose from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-5339524|Reactome:R-HSA-8981553|Reactome:R-HSA-429094|Reactome:R-HSA-450095|Reactome:R-HSA-8981564|Reactome:R-HSA-5632804|Reactome:R-HSA-8981570|Reactome:R-HSA-8981574|Reactome:R-HSA-5632871									molecular_function											owl:Class	
GO:0009519	biolink:NamedThing	middle lamella	Layer of intercellular material, chiefly pectic substances, cementing together the primary walls of contiguous cells.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Middle_lamella									cellular_component											owl:Class	
GO:1990514	biolink:NamedThing	5' transitive RNA interference	An RNA interference where the silencing signal spreads 5' along the target mRNA, outside of the initial target sequence. Typically involves the formation of secondary siRNAs formed when the initial mRNA target sequence functions as a template for 5' to 3' synthesis of new dsRNA.	tmpzr1t_l9r_go_relaxed.owl								jl	2014-10-09T15:29:31Z					biological_process											owl:Class	
GO:0106099	biolink:NamedThing	2-keto-3-deoxy-L-rhamnonate aldolase activity	Catalysis of the reaction 2-dehydro-3-deoxy-L-rhamnonate = pyruvate + (S)-lactaldehyde.	tmpzr1t_l9r_go_relaxed.owl					EC:4.1.2.53|RHEA:25784			hjd	2018-02-15T16:12:17Z					molecular_function											owl:Class	
GO:0102088	biolink:NamedThing	N-(4-hydroxybenzoyl)-L-glutamate synthetase activity	Catalysis of the reaction: 4-hydroxybenzoic acid + L-glutamate + ATP <=> H+ + N-(4-hydroxybenzoyl)-L-glutamate + AMP + diphosphoric acid.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-10887									molecular_function											owl:Class	
GO:0003711	biolink:NamedThing	transcription elongation regulator activity	A molecular function that regulates transcriptional elongation by enabling the transition from transcription initiation to elongation or by altering the elongation properties of the enzyme during the elongation phase of transcription.	tmpzr1t_l9r_go_relaxed.owl	transcriptional elongation regulator activity|transcription elongation factor activity	https://github.com/geneontology/go-ontology/issues/14398				Restored term from obsolete.								molecular_function											owl:Class	
GO:0052668	biolink:NamedThing	CTP:farnesol kinase activity	Catalysis of the reaction: 2-trans,-6-trans-farnesol + CTP = 2-trans,-6-trans-farnesyl monophosphate + CDP + H+.	tmpzr1t_l9r_go_relaxed.owl	farnesol kinase activity|CTP:2-trans,-6-trans-farnesol phosphotransferase activity|trans,trans-farnesol kinase activity|CTP:2-trans,-6-trans-farnesol kinase activity|farnesol phosphotransferase activity	https://github.com/geneontology/go-ontology/issues/21619			RHEA:51680|MetaCyc:RXN-11625|EC:2.7.1.216			ai	2011-04-11T01:19:25Z			GO:0052669		molecular_function											owl:Class	
GO:0050630	biolink:NamedThing	(iso)eugenol O-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + isoeugenol = S-adenosyl-L-homocysteine + isomethyleugenol.	tmpzr1t_l9r_go_relaxed.owl	S-adenosyl-L-methionine:isoeugenol O-methyltransferase activity|isoeugenol O-methyltransferase activity				RHEA:17081|EC:2.1.1.146|MetaCyc:2.1.1.146-RXN									molecular_function											owl:Class	
GO:0002774	biolink:NamedThing	Fc receptor mediated inhibitory signaling pathway	A series of molecular signals generated as a consequence of the binding of the Fc portion of an immunoglobulin by an Fc receptor capable of inhibiting an immune effector process contributing to an immune response. The Fc portion of an immunoglobulin is its C-terminal constant region.	tmpzr1t_l9r_go_relaxed.owl	Fc receptor mediated inhibitory signalling pathway|Fc-receptor mediated inhibitory signaling pathway													biological_process											owl:Class	
GO:0030845	biolink:NamedThing	phospholipase C-inhibiting G protein-coupled receptor signaling pathway	A G protein-coupled receptor signaling pathway which proceeds with inhibition of phospholipase C (PLC) activity and a subsequent decrease in the levels of cellular inositol trisphosphate (IP3) and diacylglycerol (DAG).	tmpzr1t_l9r_go_relaxed.owl	G-protein-coupled inhibitory pathway of phospholipase C|GPCR signaling pathway via inhibition of PLC|phospholipase C inhibition|inhibition of phospholipase C activity involved in G-protein coupled receptor signalling pathway|phospholipase C-inhibiting G-protein coupled receptor signaling pathway|GPCR signaling pathway coupled to inhibition of phospholipase C activity|PLC-inhibiting GPCR signaling pathway					This term is intended to cover steps in a GPCR signaling pathway both upstream and downstream of phospholipase C (PLC) inhibition.								biological_process											owl:Class	
GO:0102520	biolink:NamedThing	L-threonine O-3-phosphate phosphatase activity	Catalysis of the reaction: O-phospho-L-threonine + H2O = L-threonine  + hydrogenphosphate.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-14505									molecular_function											owl:Class	
GO:0070991	biolink:NamedThing	medium-chain-acyl-CoA dehydrogenase activity	Catalysis of the reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor, where the acyl group is a medium-chain fatty acid residue. A medium chain fatty acid is any fatty acid with a chain length of between C6 and C12.	tmpzr1t_l9r_go_relaxed.owl	MCAD activity				EC:1.3.99.-			mah	2009-10-29T04:11:49Z					molecular_function											owl:Class	
GO:0102468	biolink:NamedThing	wogonin 7-O-glucuronosyltransferase activity	Catalysis of the reaction: UDP-alpha-D-glucuronate + wogonin <=> UDP + wogonin 7-O-beta-D-glucuronate + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-14060|EC:2.4.1.253|RHEA:28322									molecular_function											owl:Class	
GO:0062204	biolink:NamedThing	(13S)-vitexifolin A synthase activity	Catalysis of the reaction:9alpha-copalyl diphosphate + H2O = (13S)-vitexifolin A + diphosphate.	tmpzr1t_l9r_go_relaxed.owl					RHEA:40027			dph	2020-01-03T13:24:50Z					molecular_function											owl:Class	
GO:0102525	biolink:NamedThing	2-oxoglutarate, L-arginine oxygenase (succinate-forming) activity	Catalysis of the reaction: L-argininium(1+) + 2-oxoglutarate + O2 = (3S)-3-hydroxy-L-arginine(1+) + succinate + carbon dioxide.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-14542|EC:1.14.11.41|RHEA:36607									molecular_function											owl:Class	
GO:0008733	biolink:NamedThing	L-arabinose isomerase activity	Catalysis of the reaction: L-arabinose = L-ribulose.	tmpzr1t_l9r_go_relaxed.owl	L-arabinose ketol-isomerase activity|L-arabinose aldose-ketose-isomerase activity				RHEA:14821|KEGG_REACTION:R01761|MetaCyc:ARABISOM-RXN|EC:5.3.1.4									molecular_function											owl:Class	
GO:0102616	biolink:NamedThing	oryzalexin A synthase activity	Catalysis of the reaction: oryzalexin D + NAD(P) <=> oryzalexin A + H+ + NAD(P)H.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-15464									molecular_function											owl:Class	
GO:0047480	biolink:NamedThing	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity	Catalysis of the reaction: UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysine + ATP + D-alanyl-D-alanine = phosphate + UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-D-alanyl-D-alanine + ADP.	tmpzr1t_l9r_go_relaxed.owl	UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-D-alanyl-D-alanine synthetase activity|UDP-MurNAc-pentapeptide synthetase activity|UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysine:D-alanyl-D-alanine ligase (ADP-forming)|UDPacetylmuramoylpentapeptide synthetase activity|UDP-N-acetylmuramoylalanine-D-glutamyl-lysine--D-alanyl-D-alanine ligase activity|UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanine ligase activity|MurF synthetase activity|UDP-N-acetylmuramoylalanyl-D-glutamyl-lysine-D-alanyl-D-alanine ligase activity|uridine diphosphoacetylmuramoylpentapeptide synthetase activity|UDP-MurNAc-L-Ala-D-Glu-L-Lys:D-Ala-D-Ala ligase activity|UDP-N-acetylmuramoylalanyl-tripeptide-D-alanyl-D-alanine ligase activity|UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine synthetase activity|UDP-N-acetylmuramoylalanine-D-glutamyl-lysine-D-alanyl-D-alanine ligase activity				MetaCyc:6.3.2.10-RXN|RHEA:16085|EC:6.3.2.10	Note that the enzyme UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase also has UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity (GO:0008766).								molecular_function											owl:Class	
GO:0051922	biolink:NamedThing	cholesterol sulfotransferase activity	Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + cholesterol = adenosine 3',5'-bisphosphate + cholesterol sulfate.	tmpzr1t_l9r_go_relaxed.owl					EC:2.8.2.-									molecular_function											owl:Class	
GO:0044186	biolink:NamedThing	host cell lipid droplet	Any particle of coalesced lipids in the cytoplasm of a host cell. May include associated proteins.	tmpzr1t_l9r_go_relaxed.owl	host cell lipid body|host cell lipid particle|host cell lipid adiposome							jl	2009-10-15T03:05:06Z					cellular_component											owl:Class	
GO:0043423	biolink:NamedThing	3-phosphoinositide-dependent protein kinase binding	Binding to a 3-phosphoinositide-dependent protein kinase.	tmpzr1t_l9r_go_relaxed.owl	phosphatidylinositol-3-phosphate-dependent protein kinase binding													molecular_function											owl:Class	
GO:1903576	biolink:NamedThing	response to L-arginine	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-arginine stimulus.	tmpzr1t_l9r_go_relaxed.owl								mr	2014-10-29T22:18:39Z					biological_process											owl:Class	
GO:0071132	biolink:NamedThing	alphaX-beta2 integrin-ICAM-4 complex	A protein complex that consists of an alphaX-beta2 integrin complex bound to intercellular adhesion molecule 4.	tmpzr1t_l9r_go_relaxed.owl	ITGAX-ITGB2-ICAM4 complex							mah	2009-11-13T02:28:30Z					cellular_component											owl:Class	
GO:0034046	biolink:NamedThing	poly(G) binding	Binding to a sequence of guanine residues in an RNA molecule.	tmpzr1t_l9r_go_relaxed.owl	poly(G) binding, within an RNA molecule|poly(rG) binding													molecular_function											owl:Class	
GO:0050053	biolink:NamedThing	levansucrase activity	Catalysis of the reaction: sucrose + 2,6-beta-D-fructosyl(n) = glucose + 2,6-beta-D-fructosyl(n+1).	tmpzr1t_l9r_go_relaxed.owl	sucrose:2,6-beta-D-fructan 6-beta-D-fructosyltransferase activity|sucrose 6-fructosyltransferase activity|beta-2,6-fructan:D-glucose 1-fructosyltransferase activity|sucrose 6-fructosyl transferase activity|beta-2,6-fructosyltransferase activity				EC:2.4.1.10|RHEA:13653|MetaCyc:LEVANSUCRASE-RXN									molecular_function											owl:Class	
GO:0034688	biolink:NamedThing	integrin alphaM-beta2 complex	An integrin complex that comprises one alphaM subunit and one beta2 subunit.	tmpzr1t_l9r_go_relaxed.owl	alphaM-beta2 integrin complex|Itgam-Itgb2 complex													cellular_component											owl:Class	
GO:0102476	biolink:NamedThing	pinocembrin 2-hydroxylase activity	Catalysis of the reaction: pinocembrin + NADPH + O2 + H+ <=> 2,5,7-trihydroxyflavanone + NADP + H2O.	tmpzr1t_l9r_go_relaxed.owl					RHEA:57592|MetaCyc:RXN-14083									molecular_function											owl:Class	
GO:0102527	biolink:NamedThing	8-demethylnovobiocate synthase activity	Catalysis of the reaction: 3-amino-4,7-dihydroxycoumarin + 3-dimethylallyl-4-hydroxybenzoate + ATP(4-) <=> H+ + 8-desmethylnovobiocic acid(1-) + AMP(2-) + diphosphoric acid.	tmpzr1t_l9r_go_relaxed.owl					EC:6.3.1.15|MetaCyc:RXN-14547|RHEA:36699									molecular_function											owl:Class	
GO:1904090	biolink:NamedThing	peptidase inhibitor complex	A protein complex which is capable of peptidase inhibitor activity.	tmpzr1t_l9r_go_relaxed.owl	Cathepsin-B - cystatin-A complex					An example of this is Cystatin-A in human (UniProt symbol P01040) in PMID:20860624 (inferred from physical interaction).		bhm	2015-03-26T10:16:27Z					cellular_component											owl:Class	
GO:0047769	biolink:NamedThing	arogenate dehydratase activity	Catalysis of the reaction: L-arogenate = L-phenylalanine + H2O + CO2.	tmpzr1t_l9r_go_relaxed.owl	L-arogenate hydro-lyase (decarboxylating)|L-arogenate hydro-lyase (decarboxylating; L-phenylalanine-forming)|carboxycyclohexadienyl dehydratase activity				MetaCyc:CARBOXYCYCLOHEXADIENYL-DEHYDRATASE-RXN|RHEA:12536|EC:4.2.1.91									molecular_function											owl:Class	
GO:0047774	biolink:NamedThing	cis-2-enoyl-CoA reductase (NADPH) activity	Catalysis of the reaction: acyl-CoA + NADP+ = cis-2,3-dehydroacyl-CoA + NADPH.	tmpzr1t_l9r_go_relaxed.owl	acyl-CoA:NADP+ cis-2-oxidoreductase activity|reductase, cis-2-enoyl coenzyme A|NADPH-dependent cis-enoyl-CoA reductase activity|cis-2-enoyl-coenzyme A reductase activity				MetaCyc:CIS-2-ENOYL-COA-REDUCTASE-NADPH-RXN|EC:1.3.1.37									molecular_function											owl:Class	
GO:0098972	biolink:NamedThing	anterograde dendritic transport of mitochondrion	The directed movement of mitochondria along microtubules in dendrites towards the postsynapse and away from the cell body.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0061595	biolink:NamedThing	6-deoxy-6-sulfofructose-1-phosphate aldolase activity	Catalysis of the reaction 6-deoxy-6-sulfofructose-1-phosphate = 3-sulfolactaldehyde + dihydroxyacetone phosphate.	tmpzr1t_l9r_go_relaxed.owl								dph	2014-02-10T10:05:27Z					molecular_function											owl:Class	
GO:0047953	biolink:NamedThing	glycerol 2-dehydrogenase (NADP+) activity	Catalysis of the reaction: glycerol + NADP(+) = glycerone + H(+) + NADPH.	tmpzr1t_l9r_go_relaxed.owl	dihydroxyacetone reductase (NADPH)|glycerol:NADP+ 2-oxidoreductase (glycerone-forming)|dihydroxyacetone (reduced nicotinamide adenine dinucleotide phosphate) reductase activity|dihydroxyacetone reductase activity|DHA oxidoreductase activity				MetaCyc:GLYCEROL-2-DEHYDROGENASE-NADP+-RXN|KEGG_REACTION:R01039|RHEA:12753|EC:1.1.1.156									molecular_function											owl:Class	
GO:0018812	biolink:NamedThing	3-hydroxyacyl-CoA dehydratase activity	Catalysis of the reaction: alkene-CoA + H2O = alcohol-CoA. Substrates are crotonoyl-CoA (producing 3-hydroxyacyl-CoA) and 2,3-didehydro-pimeloyl-CoA (producing 3-hydroxypimeloyl-CoA).	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-8957389									molecular_function											owl:Class	
GO:0001019	biolink:NamedThing	plastid promoter transcription regulatory region sequence-specific DNA binding	Binding to a DNA region that controls transcription by a plastid RNA polymerase. Binding may occur as a sequence specific interaction or as an interaction observed only once a factor has been recruited to the DNA by other factors.	tmpzr1t_l9r_go_relaxed.owl						plastid promoter regulatory region sequence-specific DNA binding		krc	2010-08-19T09:46:27Z					molecular_function											owl:Class	
GO:0031748	biolink:NamedThing	D1 dopamine receptor binding	Binding to a D1 dopamine receptor.	tmpzr1t_l9r_go_relaxed.owl	D1 dopamine receptor ligand|D1A dopamine receptor binding													molecular_function											owl:Class	
GO:0047561	biolink:NamedThing	3-hydroxyanthranilate oxidase activity	Catalysis of the reaction: 3-hydroxyanthranilate + O(2) = 6-imino-5-oxocyclohexa-1,3-dienecarboxylate + H(2)O(2).	tmpzr1t_l9r_go_relaxed.owl	3-hydroxyanthranilic acid oxidase activity|3-hydroxyanthranilate:oxygen oxidoreductase activity				EC:1.10.3.5|KEGG_REACTION:R02666|RHEA:17245|MetaCyc:3-HYDROXYANTHRANILATE-OXIDASE-RXN									molecular_function											owl:Class	
GO:0018815	biolink:NamedThing	3-methyl-5-hydroxy-6-(3-carboxy-3-oxopropenyl)-1H-2-pyridon hydratase-aldolase activity	Catalysis of the reaction: 3-methyl-5-hydroxy-6-(3-carboxy-3-oxopropenyl)-1H-2-pyridon + H2O = 2-oxobut-3-enanoate + 2,5,6-trihydroxy-3-methylpyridine.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-645|UM-BBD_reactionID:r0051									molecular_function											owl:Class	
GO:0032581	biolink:NamedThing	ER-dependent peroxisome organization	A process of peroxisome organization in which assembly or arrangement of constituent parts takes place in the endoplasmic reticulum.	tmpzr1t_l9r_go_relaxed.owl	endoplasmic reticulum-dependent peroxisome organization|ER-dependent peroxisome biogenesis|ER-dependent peroxisome organisation													biological_process											owl:Class	
GO:0102408	biolink:NamedThing	sn-2-glycerol-3-phosphate C16:0-DCA-CoA acyl transferase activity	Catalysis of the reaction: hexadecanedioyl-CoA + sn-glycerol 3-phosphate <=> coenzyme A + sn-2-C16:0-DCA-LPA.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-13735									molecular_function											owl:Class	
GO:0047655	biolink:NamedThing	allyl-alcohol dehydrogenase activity	Catalysis of the reaction: allyl alcohol + NADP(+) = acrolein + H(+) + NADPH.	tmpzr1t_l9r_go_relaxed.owl	allyl-alcohol:NADP+ oxidoreductase activity				EC:1.1.1.54|RHEA:12168|MetaCyc:ALLYL-ALCOHOL-DEHYDROGENASE-RXN|KEGG_REACTION:R03572									molecular_function											owl:Class	
GO:0033761	biolink:NamedThing	mugineic-acid 3-dioxygenase activity	Catalysis of the reactions: mugineic acid + 2-oxoglutarate + O2 = 3-epihydroxymugineic acid + succinate + CO2.	tmpzr1t_l9r_go_relaxed.owl	mugineic acid,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating) activity|IDS2				RHEA:14509|EC:1.14.11.25|KEGG_REACTION:R07186|MetaCyc:RXN-7982									molecular_function											owl:Class	
GO:0033803	biolink:NamedThing	kaempferol 4'-O-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + kaempferol = S-adenosyl-L-homocysteine + H(+) + kaempferide.	tmpzr1t_l9r_go_relaxed.owl	S-adenosyl-L-methionine:kaempferol 4'-O-methyltransferase activity|S-adenosyl-L-methionine:flavonoid 4'-O-methyltransferase activity|F 4'-OMT				KEGG_REACTION:R06807|EC:2.1.1.155|MetaCyc:2.1.1.155-RXN|RHEA:15105									molecular_function											owl:Class	
GO:0043800	biolink:NamedThing	hexulose-6-phosphate isomerase activity	Catalysis of the reaction: D-arabino-3-hexulose 6-phosphate = D-fructose 6-phosphate.	tmpzr1t_l9r_go_relaxed.owl	HUMPI				RHEA:25900|EC:5.3.1.27|MetaCyc:R12-RXN									molecular_function											owl:Class	
GO:0045903	biolink:NamedThing	positive regulation of translational fidelity	Any process that increases the ability of the translational apparatus to interpret the genetic code.	tmpzr1t_l9r_go_relaxed.owl	stimulation of translational fidelity|activation of translational fidelity|up regulation of translational fidelity|up-regulation of translational fidelity|upregulation of translational fidelity													biological_process											owl:Class	
GO:0004452	biolink:NamedThing	isopentenyl-diphosphate delta-isomerase activity	Catalysis of the reaction: isopentenyl diphosphate = dimethylallyl diphosphate.	tmpzr1t_l9r_go_relaxed.owl	isopentenylpyrophosphate isomerase activity|methylbutenylpyrophosphate isomerase activity|IPP isomerase activity|isopentenyl-diphosphate D-isomerase activity|isopentenylpyrophosphate delta-isomerase activity|isopentenyl-diphosphate delta3-delta2-isomerase activity				KEGG_REACTION:R01123|MetaCyc:IPPISOM-RXN|EC:5.3.3.2|RHEA:23284|Reactome:R-HSA-191382									molecular_function											owl:Class	
GO:0050090	biolink:NamedThing	mannuronate reductase activity	Catalysis of the reaction: D-mannonate + NAD(P)+ = D-mannuronate + NAD(P)H + H+.	tmpzr1t_l9r_go_relaxed.owl	mannonate dehydrogenase (NAD(P)+)|mannonate dehydrogenase activity|D-mannonate:nicotinamide adenine dinucleotide (phosphate oxidoreductase (D-mannuronate-forming))|D-mannonate:NAD(P)+ 6-oxidoreductase activity|mannonate (nicotinamide adenine dinucleotide (phosphate))dehydrogenase activity				EC:1.1.1.131|MetaCyc:MANNURONATE-REDUCTASE-RXN									molecular_function											owl:Class	
GO:0016464	biolink:NamedThing	chloroplast protein-transporting ATPase activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O = ADP + phosphate; drives the transport of proteins into the chloroplast stroma.	tmpzr1t_l9r_go_relaxed.owl	ATPase-coupled chloroplast protein transporter activity|AAA chloroplast protein-transporting ATPase				MetaCyc:3.6.3.52-RXN|EC:7.4.2.4									molecular_function											owl:Class	
GO:1990216	biolink:NamedThing	positive regulation by symbiont of host transcription	Any process in which an organism activates, maintains or increases the frequency, rate or extent of transcription in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl								ml	2013-10-10T15:45:17Z					biological_process											owl:Class	
GO:0043325	biolink:NamedThing	phosphatidylinositol-3,4-bisphosphate binding	Binding to phosphatidylinositol-3,4-bisphosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 3' and 4' positions.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0102767	biolink:NamedThing	flavanone 4'-O-methyltransferase activity	Catalysis of the reaction: (S)-naringenin + S-adenosyl-L-methionine  = 2 H+ + ponciretin + S-adenosyl-L-homocysteine.	tmpzr1t_l9r_go_relaxed.owl					RHEA:31743|MetaCyc:RXN-7777|EC:2.1.1.231									molecular_function											owl:Class	
GO:0070410	biolink:NamedThing	co-SMAD binding	Binding to a common mediator SMAD signaling protein.	tmpzr1t_l9r_go_relaxed.owl	common-partner SMAD binding|common mediator SMAD binding|common partner SMAD binding|common-mediator SMAD binding													molecular_function											owl:Class	
GO:0075000	biolink:NamedThing	response to host osmotic environment	Any process that results in a change in state or activity of the symbiont or its cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the osmotic conditions in or around its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	response of symbiont to host osmotic environment													biological_process											owl:Class	
GO:0050781	biolink:NamedThing	ortho-trichlorophenol reductive dehalogenase activity	Catalysis of the reaction: 2,4,6-trichlorophenol + 2 H+ + 2 e- = 2,4-dichlorophenol + HCl.	tmpzr1t_l9r_go_relaxed.owl	2,4,6-trichlorophenol reductive dehalogenase activity|2,4,6-TCP reductive dehalogenase activity													molecular_function											owl:Class	
GO:1990420	biolink:NamedThing	establishment of septation initiation network asymmetry	The septation initiation signaling process by which the activity of the septation initiation network (SIN) is activated asymmetrically on the spindle pole bodies.	tmpzr1t_l9r_go_relaxed.owl	establishment of SIN asymmetry							al	2014-07-16T13:51:36Z					biological_process											owl:Class	
GO:0102806	biolink:NamedThing	4-coumaroyl-CoA:cyanidin-3,5-diglucoside-6''-O-acyltransferase activity	Catalysis of the reaction: 4-coumaryl-CoA + cyanin betaine <=> shisonin + coenzyme A.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-8170									molecular_function											owl:Class	
GO:0047717	biolink:NamedThing	imidazoleacetate 4-monooxygenase activity	Catalysis of the reaction: H(+) + imidazol-4-ylacetate + NADH + O(2) = 5-hydroxyimidazole-4-acetate + H(2)O + NAD(+).	tmpzr1t_l9r_go_relaxed.owl	4-imidazoleacetate,NADH:oxygen oxidoreductase (5-hydroxylating)|imidazoleacetic hydroxylase activity|imidazoleacetic monooxygenase activity|imidazoleacetate hydroxylase activity				RHEA:19425|EC:1.14.13.5|MetaCyc:IMIDAZOLEACETATE-4-MONOOXYGENASE-RXN|KEGG_REACTION:R04066									molecular_function											owl:Class	
GO:0047532	biolink:NamedThing	2,5-dioxopiperazine hydrolase activity	Catalysis of the reaction: 2,5-dioxopiperazine + H(2)O = glycylglycine.	tmpzr1t_l9r_go_relaxed.owl	cyclo(glycylglycine) hydrolase activity|cyclo(Gly-Gly) hydrolase activity|2,5-dioxopiperazine amidohydrolase activity				RHEA:21808|EC:3.5.2.13|MetaCyc:25-DIOXOPIPERAZINE-HYDROLASE-RXN|KEGG_REACTION:R03810									molecular_function											owl:Class	
GO:0003786	biolink:NamedThing	actin lateral binding	Binding to an actin filament along its length.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1990620	biolink:NamedThing	ANPR-A receptor complex	A receptor complex composed of two ANPR-A molecules and expressed in the heart atrium in mammals; it plays a major role in the regulation of blood pressure and salt-fluid volume homeostasis. Binding of the ligand AMP in response to atrial distension (high blood volume) leads to guanylate cyclase activity of the ANPR-A receptor complex, thereby elevating intracellular cGMP levels. The end result is a reduction in blood volume and, therefore, a reduction in cardiac output and systemic blood pressure.	tmpzr1t_l9r_go_relaxed.owl	NPR1 receptor complex					An example of this is Npr1 in rat (UniProt symbol P18910) in PMID:15117952 (inferred from direct assay).		ame	2015-01-28T16:03:22Z					cellular_component											owl:Class	
GO:0052920	biolink:NamedThing	(2R)-2-hydroxy-2-methylbutanenitrile lyase activity	Catalysis of the reaction: (2R)-2-hydroxy-2-methylbutanenitrile = butan-2-one + hydrogen cyanide.	tmpzr1t_l9r_go_relaxed.owl					EC:4.1.2.46|RHEA:28170|KEGG_REACTION:R09358|MetaCyc:RXN-11733									molecular_function											owl:Class	
GO:1901744	biolink:NamedThing	2-deoxystreptamine biosynthetic process	The chemical reactions and pathways resulting in the formation of 2-deoxystreptamine.	tmpzr1t_l9r_go_relaxed.owl	2-deoxystreptamine synthesis|2-deoxystreptamine anabolism|2-deoxystreptamine formation|2-deoxystreptamine biosynthesis							yaf	2013-01-14T10:02:06Z					biological_process											owl:Class	
GO:0008784	biolink:NamedThing	alanine racemase activity	Catalysis of the reaction: L-alanine = D-alanine.	tmpzr1t_l9r_go_relaxed.owl	L-alanine racemase activity				KEGG_REACTION:R00401|EC:5.1.1.1|RHEA:20249|MetaCyc:ALARACECAT-RXN									molecular_function											owl:Class	
GO:0000492	biolink:NamedThing	box C/D snoRNP assembly	The aggregation, arrangement and bonding together of proteins and a box C/D snoRNA to form a box C/D small nucleolar ribonucleoprotein (snoRNP) complex.	tmpzr1t_l9r_go_relaxed.owl	box C/D small nucleolar ribonucleoprotein complex assembly													biological_process											owl:Class	
GO:1903292	biolink:NamedThing	protein localization to Golgi membrane	A process in which a protein is transported to, or maintained in, a location within a Golgi membrane.	tmpzr1t_l9r_go_relaxed.owl	protein localisation to Golgi membrane|protein localization in Golgi membrane|protein localisation in Golgi membrane							mah	2014-08-12T14:22:31Z					biological_process											owl:Class	
GO:0010280	biolink:NamedThing	UDP-L-rhamnose synthase activity	Catalysis of the reaction: UDP-D-glucose + NADPH + H+ = UDP-L-rhamnose + NADP+ + H2O.	tmpzr1t_l9r_go_relaxed.owl	UDP-4-keto-6-deoxy-D-glucose 3,5-epimerase-4-reductase activity				MetaCyc:RXN-5482									molecular_function											owl:Class	
GO:0018474	biolink:NamedThing	2-carboxybenzaldehyde dehydrogenase activity	Catalysis of the reaction: 2-carboxybenzaldehyde + NAD+ + H2O = NADH + 2 H+ + phthalate.	tmpzr1t_l9r_go_relaxed.owl					EC:1.2.1.-|UM-BBD_reactionID:r0490									molecular_function											owl:Class	
GO:0008465	biolink:NamedThing	glycerate dehydrogenase activity	Catalysis of the reaction: (R)-glycerate + NAD+ = hydroxypyruvate + NADH + H+.	tmpzr1t_l9r_go_relaxed.owl	hydroxypyruvate dehydrogenase activity				EC:1.1.1.29|MetaCyc:GLYCERATE-DEHYDROGENASE-RXN|RHEA:17905									molecular_function											owl:Class	
GO:0043780	biolink:NamedThing	cobalt-precorrin-5B C1-methyltransferase activity	Catalysis of the reaction: cobalt-precorrin 5B + S-adenosylmethionine = S-adenosylhomocysteine + cobalt-precorrin 6A.	tmpzr1t_l9r_go_relaxed.owl	cobalt-precorrin 5B C1-methyltransferase activity				RHEA:26285|MetaCyc:RXN-8764									molecular_function											owl:Class	
GO:0102728	biolink:NamedThing	campest-4-en-3-one,NADPH:steroid 5alpha-reductase activity	Catalysis of the reaction: (5alpha)-campestan-3-one + NADP = H+ + campest-4-en-3-one + NADPH.	tmpzr1t_l9r_go_relaxed.owl					RHEA:54416|MetaCyc:RXN-711									molecular_function											owl:Class	
GO:0140719	biolink:NamedThing	constitutive heterochromatin assembly	The assembly of constitutive heterochromatin, heterochromatin that is always in a conformation refactory to transcription.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/22325						pg	2021-10-29T13:41:09Z					biological_process											owl:Class	
GO:0050182	biolink:NamedThing	phosphate butyryltransferase activity	Catalysis of the reaction: butanoyl-CoA + phosphate = butanoyl phosphate + CoA.	tmpzr1t_l9r_go_relaxed.owl	butanoyl-CoA:phosphate butanoyltransferase activity|phosphotransbutyrylase activity				EC:2.3.1.19|MetaCyc:PHOSPHATE-BUTYRYLTRANSFERASE-RXN|KEGG_REACTION:R01174|RHEA:20892									molecular_function											owl:Class	
GO:0098604	biolink:NamedThing	adenosylselenohomocysteinase activity	Catalysis of the reaction: Se-Adenosyl-L-selenohomocysteine + H2O => Adenosine + Selenohomocysteine.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-2408532			dos	2014-04-16T10:53:22Z					molecular_function											owl:Class	
GO:0034680	biolink:NamedThing	integrin alpha10-beta1 complex	An integrin complex that comprises one alpha10 subunit and one beta1 subunit.	tmpzr1t_l9r_go_relaxed.owl	alpha10-beta1 integrin complex|ITGA10-ITGB1 complex													cellular_component											owl:Class	
GO:0047972	biolink:NamedThing	guanidinopropionase activity	Catalysis of the reaction: 3-guanidinopropanoate + H(2)O = beta-alanine + urea.	tmpzr1t_l9r_go_relaxed.owl	3-guanidinopropanoate amidinopropionase activity|GPase activity|GPH				KEGG_REACTION:R00913|RHEA:16029|EC:3.5.3.17|MetaCyc:GUANIDINOPROPIONASE-RXN									molecular_function											owl:Class	
GO:0050407	biolink:NamedThing	[glycogen-synthase-D] phosphatase activity	Catalysis of the reaction: [glycogen-synthase D] + H2O = [glycogen-synthase I] + phosphate.	tmpzr1t_l9r_go_relaxed.owl	phosphatase type 2oC|glycogen synthase phosphatase activity|uridine diphosphoglucose-glycogen glucosyltransferase phosphatase activity|UDP-glycogen glucosyltransferase phosphatase activity|UDP-glucose:glycogen 4-alpha-D-glucosyltransferase-D phosphohydrolase activity|glycogen glucosyltransferase phosphatase activity|UDPglucose:glycogen 4-alpha-D-glucosyltransferase-D phosphohydrolase activity|glycogen-synthase-D phosphatase activity|glycogen synthetase phosphatase activity|Mg2+ dependent glycogen synthase phosphatase activity|glycogen synthase D phosphatase activity|UDPglucose-glycogen glucosyltransferase phosphatase activity				EC:3.1.3.42|MetaCyc:GLYCOGEN-SYNTHASE-D-PHOSPHATASE-RXN									molecular_function											owl:Class	
GO:0052861	biolink:NamedThing	glucan endo-1,3-beta-glucanase activity, C-3 substituted reducing group	Catalysis of the endohydrolysis of (1->3)-linkages in beta-D-glucans when the glucose residue whose reducing group is involved in the linkage to be hydrolysed is itself substituted at C-3.	tmpzr1t_l9r_go_relaxed.owl	1,3-(1,3)-beta-D-glucan 3-glucanohydrolase activity|laminaranase activity|laminarinase activity				MetaCyc:3.2.1.6-RXN|EC:3.2.1.6			ai	2011-12-06T04:49:36Z					molecular_function											owl:Class	
GO:1990664	biolink:NamedThing	Nkx-2.5 complex	A transcription factor complex formed by two or more subunits of Nkx-2.5. Nkx-2.5 is an evolutionary conserved transcription factor important for the specification and differentiation of cardiomyocytes during heart development. It is also required for spleen development. It binds DNA either as a monomer, or a homodimer, or a heterodimer complex to activate or inhibit expression of genes.	tmpzr1t_l9r_go_relaxed.owl	NKX2E homodimer complex|Nkx-2.5 homodimer complex|NKX2.5 complex|NKX.2-5 homodimer complex					An example of this is Nkx-2.5 in human (UniProt symbol P52952) in PMID:22849347 (inferred from direct assay).		ame	2015-02-27T12:22:06Z					cellular_component											owl:Class	
GO:0030084	biolink:NamedThing	PSI associated light-harvesting complex I, LHCIb subcomplex	A pigment protein complex that forms part of the photosystem I associated light-harvesting complex I; contains two proteins (usually about 20 kDa); has a fluorescence maximum of 730 nm.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0034870	biolink:NamedThing	pinacolone 5-monooxygenase activity	Catalysis of the reaction: 2,2-dimethyl-3-pentanone + 1/2 O2 = 1-hydroxy-4,4-dimethylpentan-3-one.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r12979									molecular_function											owl:Class	
GO:1904824	biolink:NamedThing	anaphase-promoting complex assembly	The aggregation, arrangement and bonding together of a set of components to form an anaphase-promoting complex.	tmpzr1t_l9r_go_relaxed.owl	cyclosome formation|anaphase promoting complex formation|cyclosome assembly|anaphase promoting complex assembly|APC assembly|anaphase-promoting complex formation							mah	2015-11-23T12:28:59Z					biological_process											owl:Class	
GO:0018473	biolink:NamedThing	cis-2-methyl-5-isopropylhexa-2,5-dienal dehydrogenase activity	Catalysis of the reaction: cis-2-methyl-5-isopropylhexa-2,5-dienal + NAD+ + H2O = NADH + H+ + cis-2-methyl-5-isopropylhexa-2,5-dienoic acid.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0744									molecular_function											owl:Class	
GO:0003075	biolink:NamedThing	renal vasodilation of the peripheral vascular system involved in regulation of systemic arterial blood pressure	The renal process that modulates the force with which blood travels through the circulatory system, by vasodilation of the peripheral vascular system.	tmpzr1t_l9r_go_relaxed.owl	renal regulation of systemic arterial blood pressure by vasodilation of the peripheral vascular system													biological_process											owl:Class	
GO:0051879	biolink:NamedThing	Hsp90 protein binding	Binding to Hsp90 proteins, any of a group of heat shock proteins around 90kDa in size.	tmpzr1t_l9r_go_relaxed.owl	Hsp90 class protein binding|Hsp90 binding													molecular_function											owl:Class	
GO:0001968	biolink:NamedThing	fibronectin binding	Binding to a fibronectin, a group of related adhesive glycoproteins of high molecular weight found on the surface of animal cells, connective tissue matrices, and in extracellular fluids.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0017124	biolink:NamedThing	SH3 domain binding	Binding to a SH3 domain (Src homology 3) of a protein, small protein modules containing approximately 50 amino acid residues found in a great variety of intracellular or membrane-associated proteins.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0015478	biolink:NamedThing	oligosaccharide transporting porin activity	Enables the transfer of oligosaccharide, sized less than 1000 Da, from one side of a membrane to the other. The transmembrane portions of porins consist exclusively of beta-strands which form a beta-barrel. They are found in the outer membranes of Gram-negative bacteria, mitochondria, plastids and possibly acid-fast Gram-positive bacteria.	tmpzr1t_l9r_go_relaxed.owl	raffinose porin													molecular_function											owl:Class	
GO:0006682	biolink:NamedThing	galactosylceramide biosynthetic process	The chemical reactions and pathways resulting in the formation of galactosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of galactose by a ceramide group.	tmpzr1t_l9r_go_relaxed.owl	galactosylceramide biosynthesis|galactosylceramide anabolism|galactosylceramide formation|galactosylceramide synthesis													biological_process											owl:Class	
GO:0071124	biolink:NamedThing	alpha1-beta1 integrin-tyrosine-protein phosphatase non-receptor type 2 complex	A protein complex that consists of an alpha1-beta1 integrin complex bound to tyrosine-protein phosphatase non-receptor type 2.	tmpzr1t_l9r_go_relaxed.owl	ITGA1-ITGB1-PTPN2 complex							mah	2009-11-13T02:22:51Z					cellular_component											owl:Class	
GO:0036201	biolink:NamedThing	ent-isokaurene C2-hydroxylase activity	Catalysis of the reaction: ent-isokaurene + O2 + NADPH + H+ = ent-2alpha-hydroxyisokaurene + H2O + NADP+.	tmpzr1t_l9r_go_relaxed.owl					KEGG_REACTION:R09861|EC:1.14.14.76|RHEA:56336			bf	2012-04-20T02:21:33Z					molecular_function											owl:Class	
GO:0097177	biolink:NamedThing	mitochondrial ribosome binding	Binding to a mitochondrial ribosome.	tmpzr1t_l9r_go_relaxed.owl								pr	2011-10-11T03:03:03Z					molecular_function											owl:Class	
GO:0033898	biolink:NamedThing	Bacillus subtilis ribonuclease activity	Catalysis of the endonucleolytic cleavage to 2',3'-cyclic nucleotides.	tmpzr1t_l9r_go_relaxed.owl	ribonucleate nucleotido-2'-transferase (cyclizing) activity|proteus mirabilis RNase activity				MetaCyc:3.1.27.2-RXN|EC:4.6.1.22									molecular_function											owl:Class	
GO:0043734	biolink:NamedThing	DNA-N1-methyladenine dioxygenase activity	Catalysis of the oxidative demethylation of N1-methyladenine and N3-methylcytosine in DNA, with concomitant decarboxylation of 2-oxoglutarate and releases oxidized methyl group on N1-methyladenine and N3-methylcytosine as formaldehyde.	tmpzr1t_l9r_go_relaxed.owl	AlkB|alpha-ketoglutarate-dependent dioxygenase				Reactome:R-HSA-112118|Reactome:R-HSA-112123									molecular_function											owl:Class	
GO:1990486	biolink:NamedThing	anaerobic fatty acid catabolic process	The chemical reactions and pathways resulting in the breakdown of a fatty acid in the absence of oxygen. A fatty acid is any of the aliphatic monocarboxylic acids that can be liberated by hydrolysis from naturally occurring fats and oils. Fatty acids are predominantly straight-chain acids of 4 to 24 carbon atoms, which may be saturated or unsaturated; branched fatty acids and hydroxy fatty acids also occur, and very long chain acids of over 30 carbons are found in waxes.	tmpzr1t_l9r_go_relaxed.owl	anaerobic fatty acid degradation							tt	2014-09-20T17:25:48Z					biological_process											owl:Class	
GO:0034896	biolink:NamedThing	3-formiminopyruvate hydrolase activity	Catalysis of the reaction: 3-formiminopyruvate + H2O = 3-formylpyruvate + HN3.	tmpzr1t_l9r_go_relaxed.owl					EC:3.5.99.-|UM-BBD_reactionID:r1400									molecular_function											owl:Class	
GO:0047078	biolink:NamedThing	3-hydroxy-4-oxoquinoline 2,4-dioxygenase activity	Catalysis of the reaction: O2 + 3-hydroxy-1H-quinolin-4-one = carbon monoxide + N-formylanthranilate.	tmpzr1t_l9r_go_relaxed.owl	3-hydroxy-4-oxo-1,4-dihydroquinoline 2,4-dioxygenase activity|3-hydroxy-1H-quinolin-4-one 2,4-dioxygenase (CO-forming)|(1H)-3-hydroxy-4-oxoquinoline 2,4-dioxygenase activity|1H-3-hydroxy-4-oxoquinoline 2,4-dioxygenase activity|3-hydroxy-4(1H)-one, 2,4-dioxygenase activity|quinoline-3,4-diol 2,4-dioxygenase activity				RHEA:17949|MetaCyc:1.13.11.47-RXN|EC:1.13.11.47									molecular_function											owl:Class	
GO:0098037	biolink:NamedThing	viral DNA genome packaging, 5' extended cos packaging	The encapsulation of the viral DNA genome within the capsid, which proceeds via cleavage of the viral DNA at specific sites to produce 5' protruding ends.	tmpzr1t_l9r_go_relaxed.owl								bm	2012-07-20T11:40:47Z					biological_process											owl:Class	
GO:0102105	biolink:NamedThing	demethoxycurcumin synthase activity from feruloylacetyl-CoA	Catalysis of the reaction: feruloylacetyl-CoA + 4-coumaryl-CoA + H2O = demethoxycurcumin + 2 coenzyme A + carbon dioxide.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-11225|EC:2.3.1.219|RHEA:35139									molecular_function											owl:Class	
GO:1905793	biolink:NamedThing	protein localization to pericentriolar material	A process in which a protein is transported to, or maintained in, a location within a pericentriolar material.	tmpzr1t_l9r_go_relaxed.owl	protein localisation in pericentriolar material|protein localisation to pericentriolar material|protein localization in pericentriolar material							ha	2017-01-10T11:10:37Z					biological_process											owl:Class	
GO:0032133	biolink:NamedThing	chromosome passenger complex	A eukaryotically conserved protein complex that localizes to kinetochores in early mitosis, the spindle mid-zone in anaphase B and to the telophase midbody. It has been proposed that the passenger complex coordinates various events based on its location to different structures during the course of mitosis. Complex members include the BIR-domain-containing protein Survivin, Aurora kinase, INCENP and Borealin.	tmpzr1t_l9r_go_relaxed.owl	CPC|chromosomal passenger complex|CPC complex													cellular_component											owl:Class	
GO:0047811	biolink:NamedThing	D-alanine gamma-glutamyltransferase activity	Catalysis of the reaction: D-alanine + L-glutamine = gamma-L-glutamyl-D-alanine + NH(4)(+).	tmpzr1t_l9r_go_relaxed.owl	L-glutamine:D-alanine gamma-glutamyltransferase activity|D-alanine g-glutamyltransferase activity				MetaCyc:D-ALANINE-GAMMA-GLUTAMYLTRANSFERASE-RXN|RHEA:23556|KEGG_REACTION:R01149|EC:2.3.2.14									molecular_function											owl:Class	
GO:0016985	biolink:NamedThing	mannan endo-1,4-beta-mannosidase activity	Catalysis of the random hydrolysis of (1->4)-beta-D-mannosidic linkages in mannans, galactomannans, glucomannans, and galactoglucomannans.	tmpzr1t_l9r_go_relaxed.owl	beta-mannanase activity|endo-beta-1,4-mannase activity|endo-1,4-beta-mannanase activity|endo-beta-mannanase activity|beta-mannanase B|1,4-beta-D-mannan mannanohydrolase activity|beta-1,4-mannan 4-mannanohydrolase activity|beta-D-mannanase activity|endo-1,4-mannanase activity				EC:3.2.1.78|MetaCyc:3.2.1.78-RXN									molecular_function											owl:Class	
GO:0042084	biolink:NamedThing	5-methyltetrahydrofolate-dependent methyltransferase activity	Catalysis of the transfer of a methyl group to an acceptor molecule; dependent on the presence of 5-methyltetrahydrofolate.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0018850	biolink:NamedThing	chloromuconate cycloisomerase activity	Catalysis of the reaction: 2-chloro-2,5-dihydro-5-oxofuran-2-acetate = 3-chloro-cis,cis-muconate.	tmpzr1t_l9r_go_relaxed.owl	muconate cycloisomerase II activity|2-chloro-2,5-dihydro-5-oxofuran-2-acetate lyase (decyclizing)				RHEA:11032|UM-BBD_enzymeID:e0065|EC:5.5.1.7									molecular_function											owl:Class	
GO:1990218	biolink:NamedThing	positive regulation by symbiont of abscisic acid levels in host	Any process in which an organism activates, maintains or increases the frequency, rate or extent of the abscisic acid levels in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl								ml	2013-10-10T15:54:10Z					biological_process											owl:Class	
GO:0047912	biolink:NamedThing	galacturonokinase activity	Catalysis of the reaction: alpha-D-galacturonate + ATP = 1-phospho-alpha-D-galacturonate + ADP + 2 H(+).	tmpzr1t_l9r_go_relaxed.owl	galacturonokinase (phosphorylating) D-galacturonic acid kinase activity|ATP:D-galacturonate 1-phosphotransferase activity				KEGG_REACTION:R01980|RHEA:12965|EC:2.7.1.44|MetaCyc:GALACTURONOKINASE-RXN									molecular_function											owl:Class	
GO:0004144	biolink:NamedThing	diacylglycerol O-acyltransferase activity	Catalysis of the reaction: acyl-CoA + 1,2-diacylglycerol = CoA + triacylglycerol.	tmpzr1t_l9r_go_relaxed.owl	palmitoyl-CoA-sn-1,2-diacylglycerol acyltransferase activity|diacylglycerol acyltransferase activity|acyl-CoA:1,2-diacylglycerol O-acyltransferase activity|diglyceride O-acyltransferase activity|1,2-diacylglycerol acyltransferase activity|diglyceride acyltransferase activity				RHEA:10868|Reactome:R-HSA-8848580|MetaCyc:DIACYLGLYCEROL-O-ACYLTRANSFERASE-RXN|Reactome:R-HSA-1482889|Reactome:R-HSA-75900|EC:2.3.1.20|Reactome:R-HSA-549192									molecular_function											owl:Class	
GO:0008928	biolink:NamedThing	mannose-1-phosphate guanylyltransferase (GDP) activity	Catalysis of the reaction: alpha-D-mannose 1-phosphate + GDP + H(+) = GDP-alpha-D-mannose + phosphate.	tmpzr1t_l9r_go_relaxed.owl	mannose 1-phosphate guanylyltransferase activity|guanosine diphosphate-mannose 1-phosphate guanylyltransferase activity|GDP-mannose phosphorylase activity|GDP-mannose 1-phosphate guanylyltransferase activity|GDP mannose phosphorylase activity|guanosine diphosphomannose phosphorylase activity|GDP:mannose-1-phosphate guanylyltransferase activity|mannose 1-phosphate (guanosine diphosphate) guanylyltransferase activity|GDP-mannose pyrophosphorylase activity|GDP:D-mannose-1-phosphate guanylyltransferase activity|GDP:alpha-D-mannose-1-phosphate guanylyltransferase activity				MetaCyc:MANNPGUANYLTRANGDP-RXN|RHEA:12905|KEGG_REACTION:R00883|EC:2.7.7.22									molecular_function											owl:Class	
GO:0048922	biolink:NamedThing	posterior lateral line neuromast deposition	The process in which a migrating neuromast primordium deposits clusters of undifferentiated cells (proneuromasts) along its migratory path in the developing posterior lateral line.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0010046	biolink:NamedThing	response to mycotoxin	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mycotoxin stimulus. A mycotoxin is a toxic chemical substance produced by fungi.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0102004	biolink:NamedThing	2-octaprenyl-6-hydroxyphenol methylase activity	Catalysis of the reaction: 3-(all-trans-octaprenyl)benzene-1,2-diol + S-adenosyl-L-methionine <=> H+ + 2-methoxy-6-(all-trans-octaprenyl)phenol + S-adenosyl-L-homocysteine.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:2-OCTAPRENYL-6-OHPHENOL-METHY-RXN|RHEA:27770									molecular_function											owl:Class	
GO:0052898	biolink:NamedThing	N1-acetylspermidine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity	Catalysis of the reaction: H(2)O + N(1)-acetylspermidine + O(2) = 1,3-diaminopropane + 4-acetamidobutanal + H(2)O(2).	tmpzr1t_l9r_go_relaxed.owl					EC:1.5.3.15|RHEA:25864									molecular_function											owl:Class	
GO:0034533	biolink:NamedThing	1,2-dihydroxy-7-hydroxymethylnaphthalene dioxygenase activity	Catalysis of the reaction: 1,2-dihydroxy-7-hydroxymethylnaphthalene + O2 = 2-hydroxy-7-hydroxymethylchromene-2-carboxylate.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0764									molecular_function											owl:Class	
GO:0021809	biolink:NamedThing	neurotrophic factor signaling initiating cell movement, involved in cerebral cortex radial glia guided migration	Signaling between members of the neurotrophin family and their receptors that result in the start of cell motility as a component of the process of cerebral cortex glial-mediated radial migration.	tmpzr1t_l9r_go_relaxed.owl	neurotrophic factor signalling initiating cell movement, involved in cerebral cortex glial-mediated radial migration													biological_process											owl:Class	
GO:0000455	biolink:NamedThing	enzyme-directed rRNA pseudouridine synthesis	The intramolecular conversion of uridine to pseudouridine during ribosome biogenesis where the enzyme specifies the site that becomes pseudouridylated without using a guide RNA.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1990708	biolink:NamedThing	conditioned place preference	The associative learning process by which an animal learns and remembers an association between a neutral, unchanging environment and a putatively rewarding, internal state produced by a xenobiotic or drug.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-03-18T20:28:59Z					biological_process											owl:Class	
GO:0080118	biolink:NamedThing	brassinosteroid sulfotransferase activity	Catalysis of the reaction: a brassinosteroid + 3'-phosphoadenosine-5'-phosphosulfate = sulfated brassinosteroid + adenosine-3',5'-diphosphate. This reaction is the transfer of a sulfate group to the hydroxyl group of a brassinosteroid acceptor, producing the sulfated brassinosteroid derivative.	tmpzr1t_l9r_go_relaxed.owl								dhl	2009-04-27T03:39:36Z					molecular_function											owl:Class	
GO:0034839	biolink:NamedThing	menth-2-enone hydratase activity	Catalysis of the reaction: (5R)-menth-2-enone + H2O = (5R)-3-hydroxymenthone.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r1184									molecular_function											owl:Class	
GO:0103056	biolink:NamedThing	gibberellin A53, 2-oxoglutarate:oxygen oxidoreductase activity	Catalysis of the reaction: gibberellin A53 + O2 + 2-oxoglutarate <=> gibberellin A44 diacid + carbon dioxide + succinate.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN1F-167|RHEA:60800									molecular_function											owl:Class	
GO:0070119	biolink:NamedThing	ciliary neurotrophic factor binding	Binding to the cytokine ciliary neurotrophic factor.	tmpzr1t_l9r_go_relaxed.owl	CNTF binding													molecular_function											owl:Class	
GO:0102197	biolink:NamedThing	vinylacetate caboxylester hydrolase activity	Catalysis of the reaction: but-3-enoate + H2O <=> allyl alcohol + formate.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-12087									molecular_function											owl:Class	
GO:0018042	biolink:NamedThing	C-terminal peptidyl-histidine amidation	The formation of a C-terminal peptidyl-histidine amide by hydrolysis and oxidation of an interior His-Gly peptide in a secreted protein.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0089									biological_process											owl:Class	
GO:0019352	biolink:NamedThing	protoporphyrinogen IX biosynthetic process from glycine	The chemical reactions and pathways resulting in the formation of protoporphyrinogen IX from other compounds, including glycine.	tmpzr1t_l9r_go_relaxed.owl	protoporphyrinogen IX synthesis from glycine|protoporphyrinogen IX formation from glycine|protoporphyrinogen IX anabolism from glycine													biological_process											owl:Class	
GO:0102273	biolink:NamedThing	homophytochelatin synthase (dimmer forming) activity	Catalysis of the reaction: glutathionate + L-gamma-glutamyl-L-cysteinyl-beta-alaninate <=> gamma-Glu-Cys-gamma-Glu-Cys-beta-Ala + glycine.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-12529									molecular_function											owl:Class	
GO:0004941	biolink:NamedThing	beta2-adrenergic receptor activity	Combining with epinephrine or norepinephrine to initiate a change in cell activity via activation of a G protein, with pharmacological characteristics of beta2-adrenergic receptors.	tmpzr1t_l9r_go_relaxed.owl	beta2 adrenoceptor													molecular_function											owl:Class	
GO:0036269	biolink:NamedThing	swimming behavior	The response to external or internal stimuli that results in the locomotory process of swimming. Swimming is the self-propelled movement of an organism through the water.	tmpzr1t_l9r_go_relaxed.owl	swimming behaviour							bf	2012-07-04T10:14:49Z					biological_process											owl:Class	
GO:0018452	biolink:NamedThing	5-exo-hydroxycamphor dehydrogenase activity	Catalysis of the reaction: 5-exo-hydroxycamphor + NAD+ = NADH + H+ + 2,5-diketocamphane.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0427|RHEA:32879|MetaCyc:R542-RXN|EC:1.1.1.327									molecular_function											owl:Class	
GO:0031781	biolink:NamedThing	type 3 melanocortin receptor binding	Binding to a type 3 melanocortin receptor.	tmpzr1t_l9r_go_relaxed.owl	type 3 melanocortin receptor ligand													molecular_function											owl:Class	
GO:1904611	biolink:NamedThing	cellular response to 3,3',4,4',5-pentachlorobiphenyl	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 3,3',4,4',5-pentachlorobiphenyl stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to PCB 126							sl	2015-08-27T18:52:55Z					biological_process											owl:Class	
GO:0005111	biolink:NamedThing	type 2 fibroblast growth factor receptor binding	Binding to a type 2 fibroblast growth factor receptor (FGFR2).	tmpzr1t_l9r_go_relaxed.owl	heartless binding|FGFR2 ligand|heartless ligand|type 2 fibroblast growth factor receptor ligand|FGFR2 binding					Note that heartless is the Drosophila gene encoding the type 2 fibroblast growth factor receptor (FGFR2).								molecular_function											owl:Class	
GO:1990409	biolink:NamedThing	adrenomedullin binding	Binding to adrenomedullin (AM).	tmpzr1t_l9r_go_relaxed.owl	AM binding					An example of a protein that could be annotated to this term is CALCRL in human (Q16602) in PMID:10882736.		bhm	2014-07-02T14:37:19Z					molecular_function											owl:Class	
GO:0031813	biolink:NamedThing	P2Y2 nucleotide receptor binding	Binding to a P2Y2 nucleotide receptor.	tmpzr1t_l9r_go_relaxed.owl	P2Y2 nucleotide receptor ligand													molecular_function											owl:Class	
GO:0101016	biolink:NamedThing	FMN-binding domain binding	Binding to the FMN-binding domain of a protein.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0003064	biolink:NamedThing	regulation of heart rate by hormone	The process in which the hormones modulates the rate of heart muscle contraction. A hormone is one of a group of substances formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells, in the same organism, upon which they have a specific regulatory action.	tmpzr1t_l9r_go_relaxed.owl	regulation of the rate of heart contraction by hormone|hormonal cardiac chronotropy													biological_process											owl:Class	
GO:0102246	biolink:NamedThing	6-amino-6-deoxyfutalosine hydrolase activity	Catalysis of the reaction: aminodeoxyfutalosinate + H2O <=> dehypoxanthine futalosine + adenine.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-12346|RHEA:33079|EC:3.2.2.30									molecular_function											owl:Class	
GO:0050395	biolink:NamedThing	vitexin beta-glucosyltransferase activity	Catalysis of the reaction: UDP-D-glucose + vitexin = H(+) + UDP + vitexin 2''-O-beta-D-glucoside.	tmpzr1t_l9r_go_relaxed.owl	UDPglucose:vitexin 2''-O-beta-D-glucosyltransferase activity|UDP-glucose:vitexin 2''-O-beta-D-glucosyltransferase activity|vitexin b-glucosyltransferase activity|uridine diphosphoglucose-vitexin 2''-glucosyltransferase activity				EC:2.4.1.105|RHEA:21956|KEGG_REACTION:R03565|MetaCyc:VITEXIN-BETA-GLUCOSYLTRANSFERASE-RXN									molecular_function											owl:Class	
GO:0102656	biolink:NamedThing	1-18:2-2-trans-16:1-phosphatidylglycerol desaturase activity	Catalysis of the reaction: 1-18:2-2-trans-16:1-phosphatidylglycerol + O2 + a reduced electron acceptor <=> 1-18:3-2-trans-16:1-phosphatidylglycerol + 2 H2O + an oxidized electron acceptor.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-1727									molecular_function											owl:Class	
GO:0019736	biolink:NamedThing	peptidyl-sarcosine incorporation	The incorporation of sarcosine (N-methylglycine) into non-coded peptides.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0063									biological_process											owl:Class	
GO:0102098	biolink:NamedThing	D-galacturonate reductase activity	Catalysis of the reaction: L-galactonate + NADP = aldehydo-D-galacturonate + NADPH + H+.	tmpzr1t_l9r_go_relaxed.owl					RHEA:26345|EC:1.1.1.365|MetaCyc:RXN-11151									molecular_function											owl:Class	
GO:0050236	biolink:NamedThing	pyridoxine:NADP 4-dehydrogenase activity	Catalysis of the reaction: NADP(+) + pyridoxine = H(+) + NADPH + pyridoxal.	tmpzr1t_l9r_go_relaxed.owl	pyridoxin dehydrogenase activity|pyridoxol dehydrogenase activity|PL reductase activity|pyridoxal reductase activity|pyridoxine:NADP 4-oxidoreductase activity|pyridoxine dehydrogenase activity				KEGG_REACTION:R01708|RHEA:16129|MetaCyc:PYRIDOXINE-4-DEHYDROGENASE-RXN|EC:1.1.1.65									molecular_function											owl:Class	
GO:0021504	biolink:NamedThing	neural fold hinge point formation	The formation of the median and lateral hinge points in the neural folds. These are created by apical constriction and basal expansion of the underlying neural cells. The median hinge point extends for the entire length of the neural tube, and the lateral hinge points do not form in the spinal cord region of the neural tube.	tmpzr1t_l9r_go_relaxed.owl	neural fold furrowing													biological_process											owl:Class	
GO:0018500	biolink:NamedThing	trans-9R,10R-dihydrodiolphenanthrene dehydrogenase activity	Catalysis of the reaction: trans-9R,10R-dihydrodiolphenanthrene + NAD+ = NADH + H+ + 9,10-dihydroxyphenanthrene.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0575									molecular_function											owl:Class	
GO:0050059	biolink:NamedThing	lombricine kinase activity	Catalysis of the reaction: ATP + lombricine = ADP + N-phospholombricine.	tmpzr1t_l9r_go_relaxed.owl	ATP:lombricine N-phosphotransferase activity				RHEA:23292|MetaCyc:LOMBRICINE-KINASE-RXN|EC:2.7.3.5									molecular_function											owl:Class	
GO:0021811	biolink:NamedThing	growth factor signaling initiating cell movement involved in cerebral cortex radial glia guided migration	Signaling between growth factors and their receptors that results in the start of cell movement, where this process is involved in glial-mediated radial migration in the cerebral cortex.	tmpzr1t_l9r_go_relaxed.owl	growth factor signalling initiating cell movement involved in cerebral cortex glial-mediated radial migration|growth factor signaling initiating cell movement involved in cerebral cortex glial-mediated radial migration													biological_process											owl:Class	
GO:0050520	biolink:NamedThing	phosphatidylcholine synthase activity	Catalysis of the reaction: CDP-diacylglycerol + choline = 1,2-diacyl-sn-glycero-3-phosphocholine + CMP + H(+).	tmpzr1t_l9r_go_relaxed.owl	CDPdiglyceride-choline O-phosphatidyltransferase activity|CDP-diglyceride-choline O-phosphatidyltransferase activity|CDP-diacylglycerol:choline O-phosphatidyltransferase activity|PC synthase activity				KEGG_REACTION:R05794|MetaCyc:2.7.8.24-RXN|EC:2.7.8.24|RHEA:14597									molecular_function											owl:Class	
GO:0097674	biolink:NamedThing	SCF-YLR352W ubiquitin ligase complex	An SCF ubiquitin ligase complex in which the F-box protein is YLR352W in S. cerevisiae.	tmpzr1t_l9r_go_relaxed.owl								pr	2014-10-06T10:30:54Z					cellular_component											owl:Class	
GO:0005728	biolink:NamedThing	extrachromosomal rDNA circle	Circular DNA molecules encoding ribosomal RNA that are replicated independently of chromosomal replication. These molecules originate in the chromosome but are excised and circularized, often by intramolecular homologous recombination between direct tandem repeats.	tmpzr1t_l9r_go_relaxed.owl	extrachromosomal ribosomal DNA circle													cellular_component											owl:Class	
GO:0022033	biolink:NamedThing	telencephalon microglial cell migration	The orderly movement of microglial cells through the telencephalon.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0033954	biolink:NamedThing	alpha-neoagaro-oligosaccharide hydrolase activity	Catalysis of the hydrolysis of the 1,3-alpha-L-galactosidic linkages of neoagaro-oligosaccharides that are smaller than a hexamer, yielding 3,6-anhydro-L-galactose and D-galactose.	tmpzr1t_l9r_go_relaxed.owl	alpha-neoagarooligosaccharide hydrolase activity|alpha-NAOS hydrolase activity|alpha-neoagaro-oligosaccharide 3-glycohydrolase activity				EC:3.2.1.159|MetaCyc:3.2.1.159-RXN									molecular_function											owl:Class	
GO:0071914	biolink:NamedThing	prominosome	An extracellular membrane-bounded vesicle that contains prominin proteins (in mouse Prom1/CD33 or Prom2) and are found in body fluids including ventricular fluid, saliva, urine and seminal fluid. In the ventricular fluid of the developing mouse brain two major classes of these particles have been observed (P2 particles of 500-1000 nm and P4 particles of 50-80 nm) which likely originate from microvilli, primary cilia and/or the midbody of neuroepithelial cells. The physiological role is not known.	tmpzr1t_l9r_go_relaxed.owl	prominin-containing extracellular membrane vesicle							mah	2010-09-24T09:24:36Z					cellular_component											owl:Class	
GO:0036433	biolink:NamedThing	di-trans, poly-cis-undecaprenol kinase activity	Catalysis of the reaction: di-trans, octa-cis-undecaprenol + ATP = di-trans,octa-cis-undecaprenyl phosphate + ADP + H+.	tmpzr1t_l9r_go_relaxed.owl	ditrans,polycis-undecaprenol kinase activity				KEGG_REACTION:R05626|MetaCyc:UNDECAPRENOL-KINASE-RXN|RHEA:28122			bf	2013-09-16T14:21:12Z					molecular_function											owl:Class	
GO:0047040	biolink:NamedThing	pteridine reductase activity	Catalysis of the reaction: 5,6,7,8-tetrahydrobiopterin + 2 NADP(+) = biopterin + 2 H(+) + 2 NADPH.	tmpzr1t_l9r_go_relaxed.owl	ptr1 activity|5,6,7,8-tetrahydrobiopterin:NADP+ oxidoreductase activity|PTR1|dihydrobiopterin reduction|pteridine reductase 1 activity				EC:1.5.1.33|KEGG_REACTION:R01812|MetaCyc:1.1.1.253-RXN|RHEA:19509	Note that this function was formerly EC:1.1.1.253.								molecular_function											owl:Class	
GO:0004147	biolink:NamedThing	dihydrolipoamide branched chain acyltransferase activity	Catalysis of the reaction: acyl-CoA + dihydrolipoamide = CoA + S-acyldihydrolipoamide, where the acyl group is a branched chain.	tmpzr1t_l9r_go_relaxed.owl	dihydrolipoamide branched chain transacylase activity													molecular_function											owl:Class	
GO:1990147	biolink:NamedThing	talin binding	Binding to a talin, a family of related cytoskeletal proteins that play a role in assembly of actin filaments and migration of various cell types.	tmpzr1t_l9r_go_relaxed.owl								hjd	2013-07-25T19:49:53Z					molecular_function											owl:Class	
GO:0030751	biolink:NamedThing	licodione 2'-O-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine(1+) + licodione = 2'-O-methyllicodione + S-adenosyl-L-homocysteine + H(+).	tmpzr1t_l9r_go_relaxed.owl	S-adenosyl-L-methionine:licodione 2'-O-methyltransferase activity				EC:2.1.1.65|RHEA:18521|MetaCyc:LICODIONE-2-O-METHYLTRANSFERASE-RXN|KEGG_REACTION:R03623									molecular_function											owl:Class	
GO:0102744	biolink:NamedThing	all-trans-geranyl-geranyl diphosphate reductase activity	Catalysis of the reaction: H+ + 2-trans,6-trans,10-trans-geranylgeranyl diphosphate + NADPH = dihydrogeranylgeranyl-PP + NADP.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-7658									molecular_function											owl:Class	
GO:0036145	biolink:NamedThing	dendritic cell homeostasis	The process of regulating the proliferation and elimination of dendritic cells such that the total number of dendritic cells within a whole or part of an organism is stable over time in the absence of an outside stimulus.	tmpzr1t_l9r_go_relaxed.owl	DC homeostasis							bf	2012-03-12T11:05:36Z					biological_process											owl:Class	
GO:0098818	biolink:NamedThing	hyperpolarization of postsynaptic membrane	A process that hyerpolarizes a postsynaptic membrane relative to its resting potential.  This has an inhibitory effect on the post-synaptic cell, moving the membrane potential away from the firing threshold.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0047741	biolink:NamedThing	cetraxate benzylesterase activity	Catalysis of the reaction: benzyl cetraxate + H(2)O = benzyl alcohol + cetraxate + H(+).	tmpzr1t_l9r_go_relaxed.owl	cetraxate-benzyl-ester benzylhydrolase activity				EC:3.1.1.70|RHEA:23460|KEGG_REACTION:R03612|MetaCyc:CETRAXATE-BENZYLESTERASE-RXN									molecular_function											owl:Class	
GO:0016707	biolink:NamedThing	gibberellin 3-beta-dioxygenase activity	Catalysis of the reaction: a gibberellin + 2-oxoglutarate + O2 = a 3-beta-hydroxy-gibberellin + succinate + CO2.	tmpzr1t_l9r_go_relaxed.owl	gibberellin 3-beta-hydroxylase activity|gibberellin 3beta-dioxygenase activity|(gibberrellin-20),2-oxoglutarate: oxygen oxidoreductase (3beta-hydroxylating)|gibberellin 3beta-hydroxylase activity|(gibberellin-20),2-oxoglutarate:oxygen oxidoreductase (3beta-hydroxylating)				RHEA:10104|EC:1.14.11.15|MetaCyc:RXN1F-170									molecular_function											owl:Class	
GO:0031095	biolink:NamedThing	platelet dense tubular network membrane	The lipid bilayer surrounding the platelet dense tubular network.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0097302	biolink:NamedThing	lipoprotein biosynthetic process via diacylglyceryl transfer	The chemical reactions and pathways by which diacylglyceryl transfer leads to formation of a water-soluble protein-lipid complex.	tmpzr1t_l9r_go_relaxed.owl	lipoprotein biosynthesis (diacylglyceryl transfer)							pr	2012-05-15T01:02:02Z					biological_process											owl:Class	
GO:0102445	biolink:NamedThing	3-methylquercetin 3'-O-methyltransferase activity	Catalysis of the reaction: 3',4',5-trihydroxy-3-methoxyflavon-7-olate + S-adenosyl-L-methionine  <=> 3,3'-dimethylquercetin + S-adenosyl-L-homocysteine.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-13930									molecular_function											owl:Class	
GO:0071859	biolink:NamedThing	neuropeptide F receptor binding	Binding to a neuropeptide F receptor.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-09-10T03:23:56Z					molecular_function											owl:Class	
GO:0031736	biolink:NamedThing	CCR11 chemokine receptor binding	Binding to a CCR11 chemokine receptor.	tmpzr1t_l9r_go_relaxed.owl	CCR11 chemokine receptor ligand													molecular_function											owl:Class	
GO:0102723	biolink:NamedThing	UDP-glucose:curcumin glucosyltransferase activity	Catalysis of the reaction: UDP-alpha-D-glucose + curcumin = curcumin monoglucoside + UDP + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-7062									molecular_function											owl:Class	
GO:0015615	biolink:NamedThing	D-allose-importing ATPase activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + D-allose(out) -> ADP + phosphate + D-allose(in).	tmpzr1t_l9r_go_relaxed.owl	D-allose porter activity													molecular_function											owl:Class	
GO:0047924	biolink:NamedThing	geraniol dehydrogenase activity	Catalysis of the reaction: geraniol + NADP+ = geranial + NADPH.	tmpzr1t_l9r_go_relaxed.owl	geraniol:NADP+ oxidoreductase activity				EC:1.1.1.183|RHEA:14521|MetaCyc:GERANIOL-DEHYDROGENASE-RXN|UM-BBD_reactionID:r1163									molecular_function											owl:Class	
GO:0140602	biolink:NamedThing	nucleolar ring	Ring-like structures located at the nucleolar periphery where several nuclear factors are reversibly aggregated and sequestered during acute heat stress.	tmpzr1t_l9r_go_relaxed.owl	NuRs	https://github.com/geneontology/go-ontology/issues/20579						pg	2021-02-12T15:38:17Z					cellular_component											owl:Class	
GO:0034663	biolink:NamedThing	endoplasmic reticulum chaperone complex	A protein complex that is located in the endoplasmic reticulum and is composed of chaperone proteins, including BiP, GRP94; CaBP1, protein disulfide isomerase (PDI), ERdj3, cyclophilin B, ERp72, GRP170, UDP-glucosyltransferase, and SDF2-L1.	tmpzr1t_l9r_go_relaxed.owl	endoplasmic reticulum network complex|ER chaperone complex|ER network complex													cellular_component											owl:Class	
GO:0003406	biolink:NamedThing	retinal pigment epithelium development	The progression of the retinal pigment epithelium over time, from its initial formation to the mature structure. The retinal pigment epithelium is the melanin-containing layer of cells between the retina and the choroid that absorbs scattered and reflected light and removes waste products produced by the photoreceptor cells.	tmpzr1t_l9r_go_relaxed.owl	RPE development							dph	2009-12-21T02:04:27Z					biological_process											owl:Class	
GO:0097443	biolink:NamedThing	sorting endosome	A multivesicular body surrounded by and connected with multiple tubular compartments with associated vesicles.	tmpzr1t_l9r_go_relaxed.owl	MVB-tubule complex				NIF_Subcellular:sao1028571114			pr	2012-12-06T14:04:14Z					cellular_component											owl:Class	
GO:0098666	biolink:NamedThing	G protein-coupled serotonin receptor complex	A protein complex that is capable of G protein-coupled serotonin receptor activity.	tmpzr1t_l9r_go_relaxed.owl	G-protein coupled serotonin receptor complex	https://github.com/geneontology/go-ontology/issues/12942						dos	2016-12-21T12:28:12Z					cellular_component											owl:Class	
GO:0035440	biolink:NamedThing	tuberculosinol biosynthetic process	The chemical reactions and pathways resulting in the formation of tuberculosinol (halima-5,6,dien-15-ol), a secondary metabolite in Mycobacteria.	tmpzr1t_l9r_go_relaxed.owl	halima-5,6,dien-15-ol biosynthesis|tuberculosinol biosynthesis|halima-5,6,dien-15-ol biosynthetic process				MetaCyc:PWY-5935			bf	2010-04-09T03:36:19Z					biological_process											owl:Class	
GO:0071987	biolink:NamedThing	WD40-repeat domain binding	Binding to a WD40 repeat domain of a protein. The WD40 repeat is a short structural motif of approximately 40 amino acids, often terminating in a tryptophan-aspartic acid (W-D) dipeptide. Several of these repeats are combined to form a type of protein domain called the WD domain.	tmpzr1t_l9r_go_relaxed.owl	WD domain binding|beta-transducin repeat domain binding							mah	2010-10-22T02:53:29Z					molecular_function											owl:Class	
GO:0071085	biolink:NamedThing	alphaIIb-beta3 integrin-CD9 complex	A protein complex that consists of an alphaIIb-beta3 integrin complex bound to the cell surface protein CD9.	tmpzr1t_l9r_go_relaxed.owl	ITGA2b-ITGB3-CD9 complex							mah	2009-11-06T04:44:52Z					cellular_component											owl:Class	
GO:0036054	biolink:NamedThing	protein-malonyllysine demalonylase activity	Catalysis of the reaction: protein-malonyllysine + H2O => protein-lysine + malonate. This reaction is the removal of a malonyl group (CO-CH2-CO) from a malonylated lysine residue of a protein or peptide.	tmpzr1t_l9r_go_relaxed.owl	protein malonyl lysine demalonylation activity|peptidyl-malonyllysine demalonylase activity|protein lysine demalonylation activity							bf	2011-12-12T01:29:21Z					molecular_function											owl:Class	
GO:0102603	biolink:NamedThing	12-demethyl-elloramycin C12a O-methyltransferase activity	Catalysis of the reaction: 12-demethyl-elloramycin + S-adenosyl-L-methionine  <=> elloramycin + S-adenosyl-L-homocysteine  + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-15402									molecular_function											owl:Class	
GO:0036149	biolink:NamedThing	phosphatidylinositol acyl-chain remodeling	Remodeling the acyl chains of phosphatidylinositol, through sequential deacylation and re-acylation reactions, to generate phosphatidylinositol containing different types of fatty acid acyl chains.	tmpzr1t_l9r_go_relaxed.owl								bf	2012-03-14T01:27:02Z					biological_process											owl:Class	
GO:0003106	biolink:NamedThing	negative regulation of glomerular filtration by angiotensin	The process in which angiotensin directly decreases the rate of glomerular filtration in the kidney. Glomerular filtration is the processs whereby blood is filtered by the glomerulus into the renal tubule.	tmpzr1t_l9r_go_relaxed.owl	regulation of glomerular filtration by angiotensin|angiotensin-mediated regulation of glomerular filtration													biological_process											owl:Class	
GO:0008414	biolink:NamedThing	CDP-alcohol phosphotransferase activity	Catalysis of the transfer of a CDP-alcohol group from one compound to another.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0050358	biolink:NamedThing	tropinone reductase activity	Catalysis of the reaction: NADP(+) + pseudotropine = H(+) + NADPH + tropinone.	tmpzr1t_l9r_go_relaxed.owl	tropinone (psi-tropine-forming) reductase activity|tropinone reductase II activity|pseudotropine forming tropinone reductase activity|pseudotropine:NADP+ 3-oxidoreductase activity				MetaCyc:TROPINONE-REDUCTASE-RXN|EC:1.1.1.236|KEGG_REACTION:R06734|RHEA:24244									molecular_function											owl:Class	
GO:0097263	biolink:NamedThing	eoxin E4 synthase activity	Catalysis of the reaction: eoxin D4 + H20 = eoxin E4 + glycine.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-2161868			pr	2012-03-08T03:02:48Z					molecular_function											owl:Class	
GO:0050514	biolink:NamedThing	homospermidine synthase (spermidine-specific) activity	Catalysis of the reaction: spermidine + putrescine = sym-homospermidine + propane-1,3-diamine.	tmpzr1t_l9r_go_relaxed.owl	spermidine:putrescine 4-aminobutyltransferase (propane-1,3-diamine-forming)				EC:2.5.1.45|RHEA:11236|MetaCyc:2.5.1.45-RXN									molecular_function											owl:Class	
GO:0044480	biolink:NamedThing	envenomation resulting in positive regulation of mast cell degranulation in other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant positive regulation of blood mast cell degranulation in the bitten organism.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-01-19T02:54:37Z					biological_process											owl:Class	
GO:0047271	biolink:NamedThing	glycosaminoglycan galactosyltransferase activity	Catalysis of the reaction: glycosaminoglycan + UDP-galactose = D-galactosylglycosaminoglycan + UDP.	tmpzr1t_l9r_go_relaxed.owl	UDP-galactose:glycosaminoglycan D-galactosyltransferase activity|UDPgalactose:glycosaminoglycan D-galactosyltransferase activity|uridine diphosphogalactose-mucopolysaccharide galactosyltransferase activity				MetaCyc:2.4.1.74-RXN|EC:2.4.1.74									molecular_function											owl:Class	
GO:0005169	biolink:NamedThing	neurotrophin TRKB receptor binding	Binding to a neurotrophin TRKB receptor.	tmpzr1t_l9r_go_relaxed.owl	neurotrophin TRKB receptor ligand													molecular_function											owl:Class	
GO:0033818	biolink:NamedThing	beta-ketoacyl-acyl-carrier-protein synthase III activity	Catalysis of the reaction: acetyl-CoA + malonyl-[acyl-carrier protein] = acetoacyl-[acyl-carrier protein] + CoA + CO2.	tmpzr1t_l9r_go_relaxed.owl	3-ketoacyl-acyl carrier protein synthase III activity|KAS III|beta-ketoacyl (acyl carrier protein) synthase III activity|KASIII|acetyl-CoA:malonyl-acyl-carrier-protein C-acyltransferase activity|FabH|beta-ketoacyl-acyl carrier protein synthase III activity|beta-ketoacyl-ACP synthase III activity|3-oxoacyl:ACP synthase III activity				MetaCyc:2.3.1.180-RXN|EC:2.3.1.180|RHEA:12080									molecular_function											owl:Class	
GO:0102167	biolink:NamedThing	[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine O-N-acetyl-alpha-D-glucosaminase activity	Catalysis of the reaction: H2O + an N-acetyl-alpha-D-glucosaminyl-L-serine-[glycoprotein] <=> N-acetyl-alpha-D-glucosaminide + a [protein]-L-serine.	tmpzr1t_l9r_go_relaxed.owl					EC:3.2.1.169|MetaCyc:RXN-11892|RHEA:48876									molecular_function											owl:Class	
GO:0031504	biolink:NamedThing	peptidoglycan-based cell wall organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the peptidoglycan-based cell wall.	tmpzr1t_l9r_go_relaxed.owl	peptidoglycan-based cell wall organization and biogenesis|peptidoglycan-based cell wall organisation													biological_process											owl:Class	
GO:0050030	biolink:NamedThing	L-pipecolate dehydrogenase activity	Catalysis of the reaction: L-pipecolate + acceptor = delta1-piperideine-6-carboxylate + reduced acceptor. Delta1-piperideine-6-carboxylate is also known as 2,3,4,5-tetrahydropyridine-2-carboxylate.	tmpzr1t_l9r_go_relaxed.owl	L-pipecolate:(acceptor) 1,6-oxidoreductase activity|L-pipecolate:acceptor 1,6-oxidoreductase activity				EC:1.5.99.3|MetaCyc:L-PIPECOLATE-DEHYDROGENASE-RXN|RHEA:19777									molecular_function											owl:Class	
GO:0046979	biolink:NamedThing	TAP2 binding	Binding to the TAP2 subunit of TAP (transporter associated with antigen processing) protein.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0047946	biolink:NamedThing	glutamine N-acyltransferase activity	Catalysis of the reaction: acyl-CoA + L-glutamine = CoA + N-acyl-L-glutamine.	tmpzr1t_l9r_go_relaxed.owl	acyl-CoA:L-glutamine N-acyltransferase activity				EC:2.3.1.68|RHEA:18469|MetaCyc:GLUTAMINE-N-ACYLTRANSFERASE-RXN									molecular_function											owl:Class	
GO:0102462	biolink:NamedThing	quercetin 3-sophoroside 7-O-rhamnosyltransferase activity	Catalysis of the reaction: quercetin 3-O-beta-D-glucosyl-(1->2)-beta-D-glucoside + UDP-L-rhamnose <=> quercetin 3-O-rhamnosyl(1->2)glucoside-7-O-rhamnoside + UDP + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-14011									molecular_function											owl:Class	
GO:1990632	biolink:NamedThing	branching involved in submandibular gland morphogenesis	The process in which the branching structure of the submandibular gland is generated and organized.	tmpzr1t_l9r_go_relaxed.owl	submandibular gland ductal branching|submandibular gland branching morphogenesis							cls	2015-02-10T14:40:01Z					biological_process											owl:Class	
GO:0044679	biolink:NamedThing	methanophenazine reducing hydrogenase complex	A protein complex which catalyzes the conversion of methanophenazine and hydrogen to form dihydromethanophenazine. This typically consists of three polypeptides.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-08-09T11:07:20Z					cellular_component											owl:Class	
GO:0102061	biolink:NamedThing	endo-beta-bergamotene synthase activity	Catalysis of the reaction: 2-cis,6-cis-farnesyl diphosphate <=> (+)-endo-beta-bergamotene + diphosphoric acid.	tmpzr1t_l9r_go_relaxed.owl	(+)-endo-beta-bergamotene synthase ((2Z,6Z)-farnesyl diphosphate cyclizing)|endo-beta-bergamontene synthase activity|(2Z,6Z)-farnesyl diphosphate <=> (+)-endo-beta-bergamotene				RHEA:30467|MetaCyc:RXN-10483|EC:4.2.3.53									molecular_function											owl:Class	
GO:0044208	biolink:NamedThing	'de novo' AMP biosynthetic process	The chemical reactions and pathways resulting in the formation of adenosine monophosphate (AMP) from inosine 5'-monophosphate (IMP).	tmpzr1t_l9r_go_relaxed.owl								jl	2009-10-22T02:48:30Z					biological_process											owl:Class	
GO:1990769	biolink:NamedThing	proximal neuron projection	The portion of an axon or dendrite that is close to the neuronal cell body.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-06-10T20:30:40Z					cellular_component											owl:Class	
GO:0014830	biolink:NamedThing	arteriole smooth muscle contraction	A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the arteriole. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The arteriole is the smallest division of the artery located between the muscular arteries and the capillaries.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0110102	biolink:NamedThing	ribulose bisphosphate carboxylase complex assembly	The aggregation, arrangement and bonding together of a set of components to form a ribulose bisphosphate carboxylase complex.	tmpzr1t_l9r_go_relaxed.owl	RuBisCO assembly	https://github.com/geneontology/go-ontology/issues/19828						kmv	2018-03-15T17:24:14Z					biological_process											owl:Class	
GO:0102552	biolink:NamedThing	lipoyl synthase activity (acting on glycine-cleavage complex H protein	Catalysis of the reaction: 2 S-adenosyl-L-methionine  + a [glycine-cleavage complex H protein] N6-octanoyl-L-lysine + 2 a sulfurated [sulfur carrier] = 2 L-methionine  + 2 5'-deoxyadenosine + a [glycine-cleavage complex H protein] N6-lipoyl-L-lysine + 2 an unsulfurated [sulfur carrier].	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-14950|EC:2.8.1.8									molecular_function											owl:Class	
GO:0045996	biolink:NamedThing	negative regulation of transcription by pheromones	Any process involving pheromones that stops, prevents or reduces the rate of transcription.	tmpzr1t_l9r_go_relaxed.owl	inhibition of transcription by pheromones|down-regulation of transcription by pheromones|downregulation of transcription by pheromones|down regulation of transcription by pheromones													biological_process											owl:Class	
GO:0050503	biolink:NamedThing	trehalose 6-phosphate phosphorylase activity	Catalysis of the reaction: trehalose 6-phosphate + phosphate = glucose 6-phosphate + beta-D-glucose 1-phosphate.	tmpzr1t_l9r_go_relaxed.owl	trehalose 6-phosphate:phosphate beta-D-glucosyltransferase activity				RHEA:20864|MetaCyc:2.4.1.216-RXN|EC:2.4.1.216									molecular_function											owl:Class	
GO:0039545	biolink:NamedThing	suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity	Any process in which a virus stops, prevents, or reduces a viral-induced cytoplasmic pattern recognition receptor signaling pathway in a host organism by reducing the activity of host MAVS (mitochondrial antiviral signaling protein). MAVS is a signal transducer that lies downstream of the viral RNA receptors MDA-5 and RIG-I to coordinate host innate immune responses.	tmpzr1t_l9r_go_relaxed.owl	suppression by virus of host MAVS activity|suppression by virus of host mitochondrial antiviral-signaling protein|inhibition of host MAVS by virus	https://github.com/geneontology/go-ontology/issues/21983				This term is for annotation of viral proteins that counteract the host anti-viral innate immune response.		bf	2012-01-19T02:37:20Z					biological_process											owl:Class	
GO:0036147	biolink:NamedThing	rumination	A digestive process in which food, usually grass or hay, is swallowed into a multi-compartmented stomach, regurgitated, chewed again, and swallowed again.	tmpzr1t_l9r_go_relaxed.owl	digestive rumination							bf	2012-03-13T04:35:19Z					biological_process											owl:Class	
GO:0098036	biolink:NamedThing	viral DNA genome packaging, 3' extended cos packaging	The encapsulation of the viral DNA genome within the capsid, which proceeds via cleavage of the viral DNA at specific sites to produce 3' protruding ends.	tmpzr1t_l9r_go_relaxed.owl								bm	2012-07-20T11:38:40Z					biological_process											owl:Class	
GO:0090712	biolink:NamedThing	basal pole of outer hair cell	The end of the outer hair cell which receives and transmits neural signals.	tmpzr1t_l9r_go_relaxed.owl								tb	2016-11-01T12:57:03Z					cellular_component											owl:Class	
GO:0034814	biolink:NamedThing	7,8-dihydroxy benzo(a)pyrene dioxygenase activity	Catalysis of the reaction: benzo(a)pyrene-cis-7,8-dihydrodiol + O2 = cis-4-(7-hydroxypyren-8-yl)-2-oxobut-3-enoate.	tmpzr1t_l9r_go_relaxed.owl					EC:1.13.11.-|UM-BBD_reactionID:r1138									molecular_function											owl:Class	
GO:1901500	biolink:NamedThing	response to p-xylene	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a p-xylene stimulus.	tmpzr1t_l9r_go_relaxed.owl								tt	2012-10-16T15:23:54Z					biological_process											owl:Class	
GO:1901501	biolink:NamedThing	response to xylene	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a xylene stimulus.	tmpzr1t_l9r_go_relaxed.owl								tt	2012-10-16T15:25:47Z					biological_process											owl:Class	
GO:0103001	biolink:NamedThing	dimethylsulfoxide oxygenase activity	Catalysis of the reaction: dimethyl sulfoxide + O2 + NADPH + H+ <=> sulfonyldimethane + H2O + NADP.	tmpzr1t_l9r_go_relaxed.owl					RHEA:57956|MetaCyc:RXN-9767									molecular_function											owl:Class	
GO:0097511	biolink:NamedThing	dendritic cell dendrite	A branched cellular projection (or cytoplasmic extension) that is extended from the surface of a dendritic immune cell, and which enables the cell to sample luminal pathogens and increase the surface area for antigen presentation to T cells.	tmpzr1t_l9r_go_relaxed.owl								pr	2013-10-16T13:02:25Z					cellular_component											owl:Class	
GO:0061979	biolink:NamedThing	femoral head articular cartilage development	The process whose specific outcome is the progression of femoral head articular cartilage over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl								dph	2018-02-12T20:06:21Z					biological_process											owl:Class	
GO:0030945	biolink:NamedThing	protein tyrosine phosphatase activity, via thiol-phosphate intermediate	The catalysis of phosphate removal from a phosphotyrosine using cysteine as a nucleophile and proceed by means of a thiol-phosphate intermediate.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0102869	biolink:NamedThing	6-hydroxyflavone-glucosyltransferase activity	Catalysis of the reaction: UDP-alpha-D-glucose + 6-hydroxyflavone <=> 6-O-beta-D-glucosyl-6-hydroxyflavone + UDP + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-8354									molecular_function											owl:Class	
GO:0106313	biolink:NamedThing	methylenetetrahydrofolate reductase NADPH activity	Catalysis of the reaction: 5-methyltetrahydrofolate + NADP + = 5,10-methylenetetrahydrofolate + NADPH + H+.	tmpzr1t_l9r_go_relaxed.owl					RHEA:19817			hjd	2020-09-23T14:20:27Z					molecular_function											owl:Class	
GO:0052911	biolink:NamedThing	23S rRNA (guanine(745)-N(1))-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + guanine(745) in 23S rRNA = N(1)-methylguanine(745) in 23S rRNA + S-adenosyl-L-homocysteine.	tmpzr1t_l9r_go_relaxed.owl	ribosomal RNA(m(1)G)-methylase activity|23S rRNA m(1)G(745) methyltransferase activity|S-adenosyl-L-methionine:rRNA (guanine-1-N-)-methyltransferase activity|rlmA(I) methyltransferase activity|rRNA(m(1)G)methylase activity|ribosomal ribonucleate guanine 1-methyltransferase activity				EC:2.1.1.187|MetaCyc:RXN-11573|KEGG_REACTION:R07233|RHEA:42900									molecular_function											owl:Class	
GO:0061775	biolink:NamedThing	cohesin loading activity	Facilitating a conformational change to load a cohesin complex around sister chromatids, driven by ATP hydrolysis.	tmpzr1t_l9r_go_relaxed.owl	cohesin ATPase activity|ATP-dependent cohesin loading activity|cohesin loading ATPase	https://github.com/geneontology/go-ontology/issues/21700|https://github.com/geneontology/go-ontology/issues/14205						dph	2016-07-13T12:54:43Z					molecular_function											owl:Class	
GO:0002939	biolink:NamedThing	tRNA N1-guanine methylation	The process whereby a guanine in tRNA is methylated at position N1 of the guanine.	tmpzr1t_l9r_go_relaxed.owl	tRNA m1-guanine biosynthesis							hjd	2012-11-09T16:18:41Z					biological_process											owl:Class	
GO:1905143	biolink:NamedThing	eukaryotic translation initiation factor 2 complex assembly	The aggregation, arrangement and bonding together of a set of components to form an eukaryotic translation initiation factor 2 complex.	tmpzr1t_l9r_go_relaxed.owl	eIF-2 assembly|eukaryotic translation initiation factor 2 complex formation|eIF2 assembly|eIF-2 formation|eIF2 formation							dph	2016-04-14T00:25:51Z					biological_process											owl:Class	
GO:0003054	biolink:NamedThing	circadian regulation of systemic arterial blood pressure by the suprachiasmatic nucleus	The process in which the suprachiasmatic nucleus modulates blood pressure at different values with a regularity of approximately 24 hours.	tmpzr1t_l9r_go_relaxed.owl	SCN regulation of blood pressure|master pacemaker clock regulation of blood pressure													biological_process											owl:Class	
GO:0102186	biolink:NamedThing	4alpha-formyl,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-cholest-24-en-3beta-ol-4alpha-methyl oxidase activity	Catalysis of the reaction: 4alpha-formyl,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-cholest-24-en-3beta-ol + NADH(2-) + O2 <=> 4alpha-carboxy,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-cholest-24-en-3beta-ol + NAD(1-) + H2O.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-11948									molecular_function											owl:Class	
GO:0036443	biolink:NamedThing	dermatan 6-sulfotransferase activity	Catalysis of the reaction: 3'-phosphoadenylyl sulfate + dermatan = adenosine 3',5'-bisphosphate + dermatan 6'-sulfate.	tmpzr1t_l9r_go_relaxed.owl					KEGG_REACTION:R07288			bf	2013-10-17T10:41:48Z					molecular_function											owl:Class	
GO:0045545	biolink:NamedThing	syndecan binding	Binding to syndecan, an integral membrane proteoglycan (250-300 kDa) associated largely with epithelial cells.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0102189	biolink:NamedThing	4alpha-hydroxymethyl-5alpha-cholesta-7,24-dien-3beta-ol-4alpha-methyl oxidase activity	Catalysis of the reaction: 4alpha-hydroxymethyl-5alpha-cholesta-7,24-dien-3beta-ol + O2 + NADH(2-) + H+ <=> 4alpha-formyl-5alpha-cholesta-7,24-dien-3beta-ol + NAD(1-) + 2 H2O.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-11957									molecular_function											owl:Class	
GO:0018159	biolink:NamedThing	peptidyl-methionine oxidation	The oxidation of peptidyl-L-methionine to peptidyl-L-methionine sulfone.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0251									biological_process											owl:Class	
GO:0070532	biolink:NamedThing	BRCA1-B complex	A protein complex that contains the BRCA1-BARD1 heterodimer, BACH1 and TopBP1, and binds to DNA during S phase at DNA damage sites.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0098641	biolink:NamedThing	cadherin binding involved in cell-cell adhesion	Any cadherin binding that occurs as part of the process of cell-cell adhesion.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0050351	biolink:NamedThing	trimetaphosphatase activity	Catalysis of the reaction: H(2)O + trimetaphosphate = 2 H(+) + triphosphate.	tmpzr1t_l9r_go_relaxed.owl	trimetaphosphate hydrolase activity|inorganic trimetaphosphatase activity				RHEA:11088|EC:3.6.1.2|KEGG_REACTION:R02504|MetaCyc:TRIMETAPHOSPHATASE-RXN									molecular_function											owl:Class	
GO:0009551	biolink:NamedThing	secondary plasmodesma	A plasmodesma with a branched structure, often with many channels leading into a larger central cavity; found in older tissues and usually derived from preexisting primary plasmodesmata.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0019085	biolink:NamedThing	early viral transcription	The first phase of viral transcription that occurs after entry of the virus into the host cell, but prior to viral genome replication. It involves the transcription of genes for non-structural proteins, and for lytic viruses, the early gene products are involved in establishing control over the host cell.	tmpzr1t_l9r_go_relaxed.owl	immediate early viral mRNA transcription													biological_process											owl:Class	
GO:0071059	biolink:NamedThing	alpha6-beta1 integrin-CD151 complex	A protein complex that consists of an alpha6-beta1 integrin complex bound to the tetraspanin CD151.	tmpzr1t_l9r_go_relaxed.owl	ITGA6-ITGB1-CD151 complex							mah	2009-11-03T04:01:23Z					cellular_component											owl:Class	
GO:0023031	biolink:NamedThing	MHC class Ib protein binding, via lateral surface	Binding to a major histocompatibility complex class Ib molecules via the lateral surface.	tmpzr1t_l9r_go_relaxed.owl									2010-02-16T09:30:50Z					molecular_function											owl:Class	
GO:0010355	biolink:NamedThing	homogentisate farnesyltransferase activity	Catalysis of the reaction: homogentisic acid + farnesyl diphosphate = 2-methyl-6-farnesylplastoquinol.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0052797	biolink:NamedThing	4-O-methyl-glucuronoyl methylesterase activity	Catalysis of the reaction: [X]-4-O-methyl-D-glucuronic acid + H2O = [X]-OH + methyl-D-glucuronic acid. This reaction is the hydrolysis of the ester linkage between 4-O-methyl-D-glucuronic acid (MeGlcA) and an alcohol (-OH) group attached to a molecule, denoted here as [X].	tmpzr1t_l9r_go_relaxed.owl	glucuronoyl esterase activity													molecular_function											owl:Class	
GO:0035718	biolink:NamedThing	macrophage migration inhibitory factor binding	Binding to the cytokine, macrophage migration inhibitory factor.	tmpzr1t_l9r_go_relaxed.owl	MIF binding							bf	2011-03-03T04:27:16Z					molecular_function											owl:Class	
GO:0042309	biolink:NamedThing	homoiothermy	Any homoeostatic process in which an organism maintains its internal body temperature at a relatively constant value. This is achieved by using metabolic processes to counteract fluctuations in the temperature of the environment.	tmpzr1t_l9r_go_relaxed.owl	ice nucleation activity|antifreeze activity|ice nucleation inhibitor activity													biological_process											owl:Class	
GO:0002482	biolink:NamedThing	antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-independent	The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class Ib protein complex following intracellular transport via a pathway not requiring TAP (transporter associated with antigen processing). The peptide is typically a fragment of a larger exogenous protein which has been degraded within the cell. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E gene family.	tmpzr1t_l9r_go_relaxed.owl	TAP-independent exogenous peptide antigen processing and presentation via MHC class Ib|exogenous peptide antigen processing and presentation via MHC class Ib, TAP-independent|TAP-independent antigen processing and presentation of exogenous peptide antigen via MHC class Ib													biological_process											owl:Class	
GO:0018550	biolink:NamedThing	tetrachloro-p-hydroquinone reductive dehalogenase activity	Catalysis of the reaction: 2,3,5,6-tetrachlorohydroquinone + 2 glutathione = 2,3,6-trichlorohydroquinone + glutathione disulfide + HCl.	tmpzr1t_l9r_go_relaxed.owl	tetrachlorohydroquinone reductive dehalogenase activity				EC:1.8.99.-|UM-BBD_reactionID:r0314									molecular_function											owl:Class	
GO:0016545	biolink:NamedThing	male courtship behavior, veined wing vibration	The process during courtship where the male insect vibrates his wings. An example of this is found in Drosophila melanogaster.	tmpzr1t_l9r_go_relaxed.owl	male courtship behaviour, veined wing vibration|male courtship behavior, wing vibration|male courtship behaviour, wing vibration													biological_process											owl:Class	
GO:0045469	biolink:NamedThing	negative regulation of R8 cell spacing in compound eye	Any process that stops or prevents the correct R8 cell spacing pattern in a compound eye.	tmpzr1t_l9r_go_relaxed.owl	downregulation of R8 spacing|inhibition of R8 spacing|down-regulation of R8 spacing|down regulation of R8 spacing													biological_process											owl:Class	
GO:0008432	biolink:NamedThing	JUN kinase binding	Binding to JUN kinase, an enzyme that catalyzes the phosphorylation and activation of members of the JUN family.	tmpzr1t_l9r_go_relaxed.owl	JNK binding													molecular_function											owl:Class	
GO:0050496	biolink:NamedThing	peptidyl-L-glutamyl 5-omega-hydroxyceramide ester biosynthetic process from peptidyl-glutamine	The modification of peptidyl-glutamine residues by deamidation and esterification with omega-hydroxyceramide.	tmpzr1t_l9r_go_relaxed.owl	peptidyl-L-glutamyl 5-omega-hydroxyceramide ester anabolism from peptidyl-glutamine|peptidyl-L-glutamyl 5-omega-hydroxyceramide ester synthesis from peptidyl-glutamine|peptidyl-L-glutamyl 5-omega-hydroxyceramide ester formation from peptidyl-glutamine				RESID:AA0340									biological_process											owl:Class	
GO:0071207	biolink:NamedThing	histone pre-mRNA stem-loop binding	Binding to a conserved stem-loop structure found in histone pre-mRNAs.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-11-25T01:25:15Z					molecular_function											owl:Class	
GO:0102306	biolink:NamedThing	benzil reductase [(S)-benzoin-forming] activity	Catalysis of the reaction: (S)-benzoin + NADP(3-) <=> benzil + NADPH(4-) + H+.	tmpzr1t_l9r_go_relaxed.owl					RHEA:25968|MetaCyc:RXN-12898|EC:1.1.1.320									molecular_function											owl:Class	
GO:0050335	biolink:NamedThing	thiocyanate isomerase activity	Catalysis of the reaction: benzyl isothiocyanate = benzyl thiocyanate.	tmpzr1t_l9r_go_relaxed.owl	benzyl-thiocyanate isomerase activity|isothiocyanate isomerase activity				RHEA:10004|KEGG_REACTION:R04010|MetaCyc:THIOCYANATE-ISOMERASE-RXN|EC:5.99.1.1									molecular_function											owl:Class	
GO:0102368	biolink:NamedThing	beta-amyrin 30-monooxygenase activity	Catalysis of the reaction: beta-amyrin + NADPH + H+ + O2 <=> 30-hydroxy-beta-amyrin + NADP + H2O.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-13489									molecular_function											owl:Class	
GO:0018358	biolink:NamedThing	protein-phytochromobilin linkage via S-phytochromobilin-L-cysteine	The linkage of the chromophore phytochromobilin to phycocyanin or allophycocyanin via S-phytochromobilin-L-cysteine.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0133							GO:0018381		biological_process											owl:Class	
GO:0021816	biolink:NamedThing	extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration	The rearrangements of the microtubule cytoskeleton that result in the extension of a leading process, where this process is involved in the movement of cells along radial glial cells.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0042972	biolink:NamedThing	licheninase activity	Catalysis of the hydrolysis of (1->4)-beta-D-glucosidic linkages in beta-D-glucans containing (1->3) and (1->4) bonds.	tmpzr1t_l9r_go_relaxed.owl	lichenase activity|1,3-1,4-beta-glucan 4-glucanohydrolase activity|beta-glucanase activity|mixed linkage beta-glucanase activity|1,3-1,4-beta-D-glucan 4-glucanohydrolase activity|beta-(1->3), (1->4)-D-glucan 4-glucanohydrolase activity|endo-beta-1,3-1,4 glucanase activity|1,3;1,4-beta-glucan 4-glucanohydrolase activity|1,3;1,4-beta-glucan endohydrolase activity				MetaCyc:3.2.1.73-RXN|EC:3.2.1.73									molecular_function											owl:Class	
GO:0098650	biolink:NamedThing	peptidyl-proline 4-dioxygenase binding	Binding to a peptidyl-proline 4-dioxygenase.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1990448	biolink:NamedThing	exon-exon junction complex binding	Binding to an exon-exon junction complex, a protein complex deposited by the spliceosome upstream of messenger RNA exon-exon junctions. The exon-exon junction complex provides a binding platform for factors involved in mRNA export and nonsense-mediated mRNA decay.	tmpzr1t_l9r_go_relaxed.owl	EJC binding							sart	2014-08-06T10:02:46Z					molecular_function											owl:Class	
GO:0008805	biolink:NamedThing	carbon-monoxide oxygenase activity	Catalysis of the reaction: CO + H2O + ferrocytochrome b-561 = CO2 + 2 H+ + 2 ferricytochrome b-561.	tmpzr1t_l9r_go_relaxed.owl	carbon monoxide oxygenase activity|carbon-monoxide dehydrogenase (cytochrome b-561)|cytochrome b561|carbon monoxide:methylene blue oxidoreductase activity|carbon monoxide oxygenase (cytochrome b-561) activity|carbon monoxide oxidase activity|carbon monoxide,water:cytochrome b-561 oxidoreductase activity				Wikipedia:Carbon-monoxide_dehydrogenase_(cytochrome_b-561)|RHEA:48880|MetaCyc:RXN-21452|EC:1.2.5.3|UM-BBD_reactionID:r0650							GO:0047767|GO:0018999		molecular_function											owl:Class	
GO:0044096	biolink:NamedThing	type IV pilus	A short filamentous structure on the surface of a bacterial cell distinguished from other pili by post-translational N-methylation of the pilin monomers.	tmpzr1t_l9r_go_relaxed.owl	type IV fimbriae|TFP|type 4 pilus							jl	2009-04-22T02:52:55Z					cellular_component											owl:Class	
GO:0050310	biolink:NamedThing	sulfite dehydrogenase activity	Catalysis of the reaction: sulfite + 2 ferricytochrome c + H2O = sulfate + 2 ferrocytochrome c.	tmpzr1t_l9r_go_relaxed.owl	sulfite cytochrome c reductase activity|sulphite dehydrogenase activity|sulfite-cytochrome c oxidoreductase activity|sulfite:ferricytochrome-c oxidoreductase activity				EC:1.8.2.1|MetaCyc:SULFITE-DEHYDROGENASE-RXN|RHEA:14281									molecular_function											owl:Class	
GO:0047010	biolink:NamedThing	hydroxycyclohexanecarboxylate dehydrogenase activity	Catalysis of the reaction: (1S,3R,4S)-3,4-dihydroxycyclohexane-1-carboxylate + NAD(+) = (1S,4S)-4-hydroxy-3-oxocyclohexane-1-carboxylate + H(+) + NADH.	tmpzr1t_l9r_go_relaxed.owl	dihydroxycyclohexanecarboxylate dehydrogenase activity|(-)t-3,t-4-dihydroxycyclohexane-c-1-carboxylate-NAD oxidoreductase activity|(1S,3R,4S)-3,4-dihydroxycyclohexane-1-carboxylate:NAD+ 3-oxidoreductase activity				RHEA:10516|EC:1.1.1.166|MetaCyc:1.1.1.166-RXN|KEGG_REACTION:R05315									molecular_function											owl:Class	
GO:0047142	biolink:NamedThing	enzyme-thiol transhydrogenase (glutathione-disulfide) activity	Catalysis of the reaction: oxidized glutathione + [xanthine dehydrogenase] = reduced glutathione + xanthine-oxidase.	tmpzr1t_l9r_go_relaxed.owl	xanthine-dehydrogenase:glutathione-disulfide S-oxidoreductase activity|thiol:disulfide oxidoreductase activity|glutathione-dependent thiol:disulfide oxidoreductase activity|[xanthine-dehydrogenase]:oxidized-glutathione S-oxidoreductase activity|xanthine-dehydrogenase:oxidized-glutathione S-oxidoreductase activity|enzyme-thiol transhydrogenase (glutathione-disulphide) activity|enzyme-thiol transhydrogenase (oxidized-glutathione) activity|thiol:disulphide oxidoreductase activity				EC:1.8.4.7|MetaCyc:1.8.4.7-RXN									molecular_function											owl:Class	
GO:0106321	biolink:NamedThing	S-(hydroxymethyl)glutathione dehydrogenase NADP activity	Catalysis of the reaction: S-(hydroxymethyl)glutathione + NADP+ = S-formylglutathione + NADPH + H+.	tmpzr1t_l9r_go_relaxed.owl					RHEA:19981|EC:1.1.1.284			hjd	2020-09-23T15:26:27Z					molecular_function											owl:Class	
GO:0047035	biolink:NamedThing	testosterone dehydrogenase (NAD+) activity	Catalysis of the reaction: testosterone + NAD+ = androst-4-ene-3,17-dione + NADH.	tmpzr1t_l9r_go_relaxed.owl	17-ketoreductase activity|testosterone 17beta-dehydrogenase activity|17beta-hydroxysteroid:NAD+ 17-oxidoreductase activity|3alpha(17beta)-HSD|3-alpha(17-beta)-hydroxysteroid dehydrogenase (NAD+) activity|3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)|testosterone 17-beta-dehydrogenase (NAD+) activity|3alpha(or 17beta)-hydroxysteroid:NAD+ oxidoreductase activity|testosterone 17b-dehydrogenase activity|17-beta-HSD activity|3alpha,17beta-hydroxy steroid dehydrogenase activity|17beta-HSD				KEGG_REACTION:R01836|RHEA:14929|MetaCyc:1.1.1.239-RXN|EC:1.1.1.239|Wikipedia:3alpha(17beta)-hydroxysteroid_dehydrogenase_(NAD+)|MetaCyc:TESTOSTERONE-17-BETA-DEHYDROGENASE-RXN							GO:0050327		molecular_function											owl:Class	
GO:0018168	biolink:NamedThing	protein-phycoerythrobilin linkage via S-phycoerythrobilin-L-cysteine	The linkage of the chromophore phycoerythrobilin to phycoerythrocyanin via S-phycoerythrobilin-L-cysteine.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0132									biological_process											owl:Class	
GO:0005600	biolink:NamedThing	collagen type XIII trimer	A collagen homotrimer of alpha1(XIII) chains; type XIII collagen triple helices span the plasma membrane.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0102208	biolink:NamedThing	2-polyprenyl-6-hydroxyphenol methylase activity	Catalysis of the reaction: S-adenosyl-L-methionine  + a 3-(all-trans-polyrenyl)benzene-1,2-diol <=> S-adenosyl-L-homocysteine  + H+ + a 2-methoxy-6-(all-trans-polyprenyl)phenol.	tmpzr1t_l9r_go_relaxed.owl					RHEA:31411|MetaCyc:RXN-12160									molecular_function											owl:Class	
GO:0031515	biolink:NamedThing	tRNA (m1A) methyltransferase complex	A protein complex involved in the catalysis of the formation of the modified nucleotide 1-methyladenosine (m1A) in tRNA. In yeast, it is a heterotetramer of two subunits, Gcd10p and Gcd14p, while in bacteria and archaea it is a homotetramer.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0098959	biolink:NamedThing	retrograde dendritic transport of mitochondrion	The directed movement of mitochondria along microtubules in dendrites towards the cell body and away from the postsynapse.	tmpzr1t_l9r_go_relaxed.owl	retrograde dendrite transport of mitochondria													biological_process											owl:Class	
GO:0034559	biolink:NamedThing	bisphenol A hydroxylase B activity	Catalysis of the reaction: bisphenol A + NADH + H+ + O2 = 1,2-bis(4-hydroxyphenyl)-2-propanol + NAD+ + H2O.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0860									molecular_function											owl:Class	
GO:0047755	biolink:NamedThing	isocitrate epimerase activity	Catalysis of the reaction: D-threo-isocitrate = D-erythro-isocitrate.	tmpzr1t_l9r_go_relaxed.owl	(1R,2S)-1-hydroxypropane-1,2,3-tricarboxylate 1-epimerase activity				KEGG_REACTION:R02318|EC:5.1.2.6|RHEA:10820|MetaCyc:ISOCITRATE-EPIMERASE-RXN									molecular_function											owl:Class	
GO:0047416	biolink:NamedThing	arylalkyl acylamidase activity	Catalysis of the reaction: H2O + N-acetylarylalkylamine = acetate + arylalkylamine.	tmpzr1t_l9r_go_relaxed.owl	aralkyl acylamidase activity|N-acetylarylalkylamine amidohydrolase activity				MetaCyc:3.5.1.76-RXN|RHEA:10352|EC:3.5.1.76									molecular_function											owl:Class	
GO:0033444	biolink:NamedThing	AAG codon-amino acid adaptor activity	A triplet codon-amino acid adaptor activity that recognizes an AAG codon.	tmpzr1t_l9r_go_relaxed.owl	lysine tRNA					Note that in the standard genetic code, AAG codes for lysine.								molecular_function											owl:Class	
GO:0017168	biolink:NamedThing	5-oxoprolinase (ATP-hydrolyzing) activity	Catalysis of the reaction: 5-oxo-L-proline + ATP + 2 H(2)O = L-glutamate + ADP + 2 H(+) + phosphate.	tmpzr1t_l9r_go_relaxed.owl	pyroglutamic hydrolase activity|L-pyroglutamate hydrolase activity|pyroglutamase activity|5-oxo-L-prolinase activity|pyroglutamate hydrolase activity|5-oxo-L-proline amidohydrolase (ATP-hydrolysing)|5-oxoprolinase (ATP-hydrolysing)|pyroglutamase (ATP-hydrolyzing) activity|5-OPase activity|oxoprolinase activity|pyroglutamase (ATP-hydrolysing)|5-oxoprolinase activity				RHEA:10348|MetaCyc:5-OXOPROLINASE-ATP-HYDROLYSING-RXN|Wikipedia:5-oxoprolinase_(ATP-hydrolysing)|Reactome:R-HSA-5603208|EC:3.5.2.9|KEGG_REACTION:R00251|Reactome:R-HSA-1247935									molecular_function											owl:Class	
GO:0035128	biolink:NamedThing	post-embryonic forelimb morphogenesis	The process, occurring after embryonic development, by which the anatomical structures of the forelimb are generated and organized. The forelimbs are the front limbs of an organism.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0052586	biolink:NamedThing	oxidoreductase activity, acting on other nitrogenous compounds as donors, with a quinone or similar compound as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which a nitrogenous group, excluding NH and NH2 groups, acts as a hydrogen or electron donor and reduces a quinone or similar compound.	tmpzr1t_l9r_go_relaxed.owl					EC:1.7.5.-			ai	2010-08-13T10:34:37Z					molecular_function											owl:Class	
GO:0150043	biolink:NamedThing	structural constituent of synapse-associated extracellular matrix	The action of a molecule that contributes to the structural integrity of the extracellular matrix of the perisynaptic space (the extracellular space adjacent to the synapse) and the synaptic cleft.	tmpzr1t_l9r_go_relaxed.owl	synapse-associated extracellular matrix structural constituent|structural constituent of extra-synaptic extracellular matrix|extra-synaptic extracellular matrix structural constituent							bc	2018-04-19T13:42:40Z					molecular_function											owl:Class	
GO:0009917	biolink:NamedThing	sterol 5-alpha reductase activity	Catalysis of the removal of a C-5 double bond in the B ring of a sterol.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0018451	biolink:NamedThing	epoxide dehydrogenase activity	Catalysis of the reaction: ethene oxide + NAD+ + CoA-SH = NADH + H+ + acetyl-CoA.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0595									molecular_function											owl:Class	
GO:0003999	biolink:NamedThing	adenine phosphoribosyltransferase activity	Catalysis of the reaction: AMP + diphosphate = adenine + 5-phospho-alpha-D-ribose 1-diphosphate.	tmpzr1t_l9r_go_relaxed.owl	APRT activity|adenosine phosphoribosyltransferase activity|adenine phosphoribosylpyrophosphate transferase activity|transphosphoribosidase activity|adenylate pyrophosphorylase activity|AMP:diphosphate phospho-D-ribosyltransferase activity|AMP-pyrophosphate phosphoribosyltransferase activity|AMP diphosphorylase activity|AMP pyrophosphorylase activity|adenylic pyrophosphorylase activity				RHEA:16609|MetaCyc:ADENPRIBOSYLTRAN-RXN|EC:2.4.2.7|Reactome:R-HSA-74213									molecular_function											owl:Class	
GO:0102753	biolink:NamedThing	chlorophyllide b:geranyl-geranyl diphosphate geranyl-geranyltransferase activity	Catalysis of the reaction: H+ + chlorophyllide b(1-) + 2-trans,6-trans,10-trans-geranylgeranyl diphosphate <=> geranylgeranyl-chlorophyll b + diphosphoric acid.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-7673									molecular_function											owl:Class	
GO:0035683	biolink:NamedThing	memory T cell extravasation	The migration of a memory T cell from the blood vessels into the surrounding tissue. A memory T cell is a distinctly differentiated long-lived T cell that has the phenotype CD45RO-positive and CD127-positive.	tmpzr1t_l9r_go_relaxed.owl	memory T-cell extravasation							bf	2011-02-23T01:10:02Z					biological_process											owl:Class	
GO:0036188	biolink:NamedThing	abieta-7,13-dien-18-al dehydrogenase activity	Catalysis of the reaction: abieta-7,13-diene-18-al + H2O + NAD+ = abieta-7,13-diene-18-oate + NADH + H+.	tmpzr1t_l9r_go_relaxed.owl	abietadienal dehydrogenase				KEGG_REACTION:R06357|EC:1.2.1.74|MetaCyc:1.2.1.74-RXN|RHEA:26225			bf	2012-04-18T01:46:19Z					molecular_function											owl:Class	
GO:1990353	biolink:NamedThing	Fused-Smurf ubiquitin ligase complex	A ubiquitin ligase complex. In D. melanogaster, it regulates ubiquitination and proteolysis of the BMP receptor Thickveins in cystoblasts, potentially by controlling Tkv ubiquitination and degradation.	tmpzr1t_l9r_go_relaxed.owl						An example of this is FUSED in Drosophila melanogaster (UniProt symbol P23647) in PMID:21145463 (inferred from direct assay).		bhm	2014-03-27T14:02:09Z					cellular_component											owl:Class	
GO:0004485	biolink:NamedThing	methylcrotonoyl-CoA carboxylase activity	Catalysis of the reaction: 3-methylbut-2-enoyl-CoA + ATP + bicarbonate = trans-3-methylglutaconyl-CoA + ADP + 2 H(+) + phosphate.	tmpzr1t_l9r_go_relaxed.owl	methylcrotonyl coenzyme A carboxylase activity|beta-methylcrotonyl CoA carboxylase activity|3-methylcrotonoyl-CoA:carbon-dioxide ligase (ADP-forming)|beta-methylcrotonyl coenzyme A carboxylase activity|beta-methylcrotonyl-CoA carboxylase activity|MCCC activity|methylcrotonyl-CoA carboxylase activity				KEGG_REACTION:R04138|Reactome:R-HSA-508308|EC:6.4.1.4|Reactome:R-HSA-70773|RHEA:13589|MetaCyc:METHYLCROTONYL-COA-CARBOXYLASE-RXN									molecular_function											owl:Class	
GO:0002498	biolink:NamedThing	proteolysis within endoplasmic reticulum associated with antigen processing and presentation	The hydrolysis of a peptide bond or bonds within a protein by ER resident proteases contributing to antigen processing and presentation.	tmpzr1t_l9r_go_relaxed.owl	endoplasmic reticulum proteolysis associated with antigen processing and presentation|ER proteolysis associated with antigen processing and presentation|proteolysis within ER associated with antigen processing and presentation													biological_process											owl:Class	
GO:0045518	biolink:NamedThing	interleukin-22 receptor binding	Binding to an interleukin-22 receptor.	tmpzr1t_l9r_go_relaxed.owl	IL-22|interleukin-22 receptor ligand													molecular_function											owl:Class	
GO:1990606	biolink:NamedThing	membrane scission GTPase motor activity	Generation of a 'twisting' activity resulting in the scission of a membrane, driven by GTP hydrolysis.	tmpzr1t_l9r_go_relaxed.owl								vw	2015-01-19T14:26:50Z					molecular_function											owl:Class	
GO:0009347	biolink:NamedThing	aspartate carbamoyltransferase complex	A multienzyme complex that catalyzes the formation N-carbamoyl-L-aspartate from carbamoyl phosphate and L-aspartate. It exhibits a variety of architectural organizations, but in all microorganisms the core catalytic component is a homotrimer of approximately 34 kDa polypeptides.	tmpzr1t_l9r_go_relaxed.owl						Note that in eukaryotes, aspartate carbamoyltransferase is usually a single polypeptide, not a complex, and should therefore not be annotated to this component term.								cellular_component											owl:Class	
GO:0009014	biolink:NamedThing	succinyl-diaminopimelate desuccinylase activity	Catalysis of the reaction: N-succinyl-LL-2,6-diaminopimelate + H(2)O = LL-2,6-diaminopimelate + succinate.	tmpzr1t_l9r_go_relaxed.owl	N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase activity|N-succinyl-L-alpha,epsilon-diaminopimelic acid deacylase activity				MetaCyc:SUCCDIAMINOPIMDESUCC-RXN|KEGG_REACTION:R02734|RHEA:22608|EC:3.5.1.18									molecular_function											owl:Class	
GO:0052871	biolink:NamedThing	alpha-tocopherol omega-hydroxylase activity	Catalysis of the reaction: alpha-tocopherol + O2 + NADPH + H+ = 13'-hydroxy-alpha-tocopherol + NADP+ + H2O .	tmpzr1t_l9r_go_relaxed.owl	alpha-tocopherol 13-hydroxylase activity				MetaCyc:RXN-11003			ai	2012-01-30T03:06:27Z					molecular_function											owl:Class	
GO:0018698	biolink:NamedThing	vinyl chloride reductive dehalogenase activity	Catalysis of the reaction: vinyl chloride + 2 H+ + 2 e- = HCl + ethene.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0352|EC:1.97.1.-|MetaCyc:VCREDCHLOR-RXN									molecular_function											owl:Class	
GO:0052605	biolink:NamedThing	gamma-tocopherol cyclase activity	Catalysis of the reaction: 2,3-dimethyl-6-phytyl-1,4-benzoquinone = gamma-tocopherol.	tmpzr1t_l9r_go_relaxed.owl					KEGG_REACTION:R07502|RHEA:37983|MetaCyc:RXN-2543									molecular_function											owl:Class	
GO:0003034	biolink:NamedThing	detection of increased carbon dioxide by aortic body chemoreceptor signaling	The process in which information about the levels of carbon dioxide are received and are converted to a molecular signal by chemoreceptors in an aortic body.	tmpzr1t_l9r_go_relaxed.owl	detection of increased carbon dioxide by aortic body chemoreceptor signalling													biological_process											owl:Class	
GO:1905218	biolink:NamedThing	cellular response to astaxanthin	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an astaxanthin stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to (3S,3'S)-3,3'-dihydroxy-beta,beta-carotene-4,4'-dione							sl	2016-06-06T21:30:09Z					biological_process											owl:Class	
GO:0033791	biolink:NamedThing	3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA 24-hydroxylase activity	Catalysis of the reaction: (25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oyl-CoA + H2O + acceptor = (24R,25R)-3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestan-26-oyl-CoA + reduced acceptor.	tmpzr1t_l9r_go_relaxed.owl	3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oate 24-hydroxylase activity|(25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oyl-CoA:acceptor 24-oxidoreductase (24R-hydroxylating) activity|THCA-CoA oxidase activity|trihydroxycoprostanoyl-CoA oxidase activity|3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA oxidase activity|THC-CoA oxidase activity				MetaCyc:1.17.99.3-RXN|RHEA:15733|EC:1.17.99.3									molecular_function											owl:Class	
GO:0018627	biolink:NamedThing	2-aminobenzenesulfonate 2,3-dioxygenase activity	Catalysis of the reaction: 2-aminobenzenesulfonate + 2 H(+) + NADH + O(2) = 2,3-dihydroxybenzenesulfonate + NAD(+) + NH(4)(+). 2,3-dihydroxybenzenesulfonate is also known as 3-sulfocatechol.	tmpzr1t_l9r_go_relaxed.owl	2-aminobenzenesulfonate,NADH:oxygen oxidoreductase (2,3-hydroxylating, ammonia-forming)|2-aminobenzenesulphonate dioxygenase activity|2-aminosulfobenzene 2,3-dioxygenase activity|2-aminobenzenesulphonate 2,3-dioxygenase activity|2-aminobenzenesulfonate dioxygenase activity				RHEA:23468|KEGG_REACTION:R05156|UM-BBD_reactionID:r0218|MetaCyc:2ASDOSALCAL-RXN|EC:1.14.12.14							GO:0018605		molecular_function											owl:Class	
GO:0034211	biolink:NamedThing	GTP-dependent protein kinase activity	GTP dependent catalysis of the reaction: ATP + a protein serine/threonine = ADP + protein serine/threonine phosphate.	tmpzr1t_l9r_go_relaxed.owl						The reaction requires the presence of GTP.								molecular_function											owl:Class	
GO:0061840	biolink:NamedThing	high-affinity ferrous iron transmembrane transporter activity	Enables the transfer of ferrous iron (Fe(II) or Fe2+) ions from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.	tmpzr1t_l9r_go_relaxed.owl	high-affinity ferrous iron uptake transmembrane transporter activity|high affinity ferrous uptake transmembrane transporter activity													molecular_function											owl:Class	
GO:0051215	biolink:NamedThing	RNAi-mediated antiviral immunity against DNA virus	Gene silencing induced by DNA viruses leading to a sequence-specific degradation of target mRNAs or post-transcriptional gene silencing.  In plants, DCL3 is the primary Dicer to detect DNA viruses.	tmpzr1t_l9r_go_relaxed.owl	DNA virus induced gene silencing|DNA VIGS|DNA virus-induced gene silencing	https://github.com/geneontology/go-ontology/issues/19958												biological_process											owl:Class	
GO:0102927	biolink:NamedThing	beta-chaconine rhamnosyltransferase activity	Catalysis of the reaction: beta-chaconine + UDP-L-rhamnose = H+ + alpha-chaconine + UDP.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-8883									molecular_function											owl:Class	
GO:0106306	biolink:NamedThing	protein serine phosphatase activity	Catalysis of the reaction: protein serine phosphate + H2O = protein serine + phosphate.	tmpzr1t_l9r_go_relaxed.owl					RHEA:20629|EC:3.1.3.16			hjd	2020-09-09T19:36:32Z					molecular_function											owl:Class	
GO:0009293	biolink:NamedThing	transduction	The transfer of genetic information to a bacterium from a bacteriophage or between bacterial or yeast cells mediated by a phage vector.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Transduction_(genetics)									biological_process											owl:Class	
GO:0099141	biolink:NamedThing	cellular response to protozoan	Any process that results in a change in state or activity of a cell  (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a protozoan.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0050396	biolink:NamedThing	vomifoliol 4'-dehydrogenase activity	Catalysis of the reaction: (6S,9R)-6-hydroxy-3-oxo-alpha-ionol + NAD(+) = (6S)-6-hydroxy-3-oxo-alpha-ionone + H(+) + NADH.	tmpzr1t_l9r_go_relaxed.owl	vomifoliol:NAD+ 4'-oxidoreductase activity				RHEA:22804|KEGG_REACTION:R04412|EC:1.1.1.221|MetaCyc:VOMIFOLIOL-4-DEHYDROGENASE-RXN									molecular_function											owl:Class	
GO:0035717	biolink:NamedThing	chemokine (C-C motif) ligand 7 binding	Binding to chemokine (C-C motif) ligand 7.	tmpzr1t_l9r_go_relaxed.owl	CCL7 binding							bf	2011-03-03T04:25:41Z					molecular_function											owl:Class	
GO:0045485	biolink:NamedThing	omega-6 fatty acid desaturase activity	Catalysis of the introduction of an omega-6 double bond into the fatty acid hydrocarbon chain.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-2046089|Reactome:R-HSA-2046092									molecular_function											owl:Class	
GO:0031637	biolink:NamedThing	regulation of neuronal synaptic plasticity in response to neurotrophin	The process in which a neurotrophic factor induces neuronal synaptic plasticity, the ability of neuronal synapses to change as circumstances require. They may alter function, such as increasing or decreasing their sensitivity, or they may increase or decrease in actual numbers.	tmpzr1t_l9r_go_relaxed.owl	neurotrophin-induced neuronal synaptic plasticity													biological_process											owl:Class	
GO:0003958	biolink:NamedThing	NADPH-hemoprotein reductase activity	Catalysis of the reaction: NADPH + H+ + n oxidized hemoprotein = NADP+ + n reduced hemoprotein.	tmpzr1t_l9r_go_relaxed.owl	NADPH--ferrihemoprotein reductase activity|NADP--cytochrome c reductase activity|NADPH--ferricytochrome c oxidoreductase activity|ferrihemoprotein P-450 reductase activity|dihydroxynicotinamide adenine dinucleotide phosphate-cytochrome c reductase activity|NADPH--cytochrome P450 reductase activity|NADPH-cytochrome P-450 oxidoreductase activity|TPNH-cytochrome c reductase activity|TPNH(2) cytochrome c reductase activity|NADPH:ferrihemoprotein oxidoreductase activity|aldehyde reductase (NADPH-dependent) activity|CPR activity|NADPH:cytochrome c reductase activity|NADPH-dependent cytochrome c reductase activity|NADPH--cytochrome c oxidoreductase activity|TPNH2 cytochrome c reductase activity|NADPH-cytochrome p-450 reductase activity|NADPH--cytochrome c reductase activity|FAD-cytochrome c reductase activity|reduced nicotinamide adenine dinucleotide phosphate-cytochrome c reductase activity|NADPH:P-450 reductase activity|NADPH:P450 reductase activity|NADPH-ferrihemoprotein reductase activity|reductase, cytochrome c (reduced nicotinamide adenine dinucleotide phosphate) activity|cytochrome c reductase (reduced nicotinamide adenine dinucleotide phosphate, NADPH, NADPH-dependent) activity|cytochrome P-450 reductase activity|POR|cytochrome P450 reductase activity|NADPH:hemoprotein oxidoreductase activity|NADPH:cytochrome P450 reductase activity|NADPH--cytochrome P450 oxidoreductase activity|NADP--cytochrome reductase activity				EC:1.6.2.4|RHEA:24040|Reactome:R-HSA-76494|MetaCyc:NADPH--FERRIHEMOPROTEIN-REDUCTASE-RXN									molecular_function											owl:Class	
GO:0035858	biolink:NamedThing	eosinophil fate determination	The cell fate determination process in which a cell becomes capable of differentiating autonomously into an eosinophil cell regardless of its environment; upon determination, the cell fate cannot be reversed.	tmpzr1t_l9r_go_relaxed.owl	eosinophil cell fate determination							bf	2011-05-17T10:43:35Z					biological_process											owl:Class	
GO:0005522	biolink:NamedThing	profilin binding	Binding to profilin, an actin-binding protein that forms a complex with G-actin and prevents it from polymerizing to form F-actin.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0044678	biolink:NamedThing	CoB-CoM heterodisulfide reductase complex	A protein complex that in Methanobacterium thermoautotrophicum is composed of six subunits, and in Methanosarcina barkeri contains is composed of either two subunits or nine subunits. Catalyzes the conversion of coenzyme B, coenzyme M, and methanophenazine to form N-{7-[(2-sulfoethyl)dithio]heptanoyl}-3-O-phospho-L-threonine and dihydromethanophenazine.	tmpzr1t_l9r_go_relaxed.owl	coenzyme M-7-mercaptoheptanoylthreonine-phosphate-heterodisulfide hydrogenase complex|hydrogen:coenzyme-M-7-mercaptoheptanoylthreonine-phosphate-heterodisulfide oxidoreductase complex							jl	2012-08-09T11:01:43Z					cellular_component											owl:Class	
GO:0018631	biolink:NamedThing	phenylacetate hydroxylase activity	Catalysis of the reaction: phenylacetate + NADH + O2 = NAD+ + OH- + 2-hydroxyphenylacetate.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0036|EC:1.14.13.-									molecular_function											owl:Class	
GO:0140290	biolink:NamedThing	peptidyl-serine ADP-deribosylation	The removal of ADP-ribose from ADP-ribosylserine.	tmpzr1t_l9r_go_relaxed.owl								pg	2018-11-22T14:32:30Z					biological_process											owl:Class	
GO:0047391	biolink:NamedThing	alkylglycerophosphoethanolamine phosphodiesterase activity	Catalysis of the reaction: H2O + 1-alkyl-sn-glycero-3-phosphoethanolamine = ethanolamine + 1-alkyl-sn-glycerol 3-phosphate.	tmpzr1t_l9r_go_relaxed.owl	1-alkyl-sn-glycero-3-phosphoethanolamine ethanolaminehydrolase activity|lysophospholipase D activity				RHEA:15965|EC:3.1.4.39|MetaCyc:3.1.4.39-RXN									molecular_function											owl:Class	
GO:0080045	biolink:NamedThing	quercetin 3'-O-glucosyltransferase activity	Catalysis of the transfer of a glucosyl group from UDP-glucose to the 3'-hydroxy group of a quercetin molecule.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0009763	biolink:NamedThing	NAD-malic enzyme C4 photosynthesis	The process of C4 photosynthesis, as it occurs in plants in which the enzyme decarboxylating C4 acids in the bundle sheath is NAD-malic enzyme.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0031735	biolink:NamedThing	CCR10 chemokine receptor binding	Binding to a CCR10 chemokine receptor.	tmpzr1t_l9r_go_relaxed.owl	CCR10 chemokine receptor ligand													molecular_function											owl:Class	
GO:0010076	biolink:NamedThing	maintenance of floral meristem identity	The process in which an organism retains a population of floral meristem cells, preventing the commitment of all stem cell progeny to a differentiated cell fate.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0042271	biolink:NamedThing	susceptibility to natural killer cell mediated cytotoxicity	The process of causing a cell to become susceptible to natural killer cell mediated cytotoxicity.	tmpzr1t_l9r_go_relaxed.owl	susceptibility to NK cell mediated cell death|susceptibility to natural killer cell mediated cell killing|susceptibility to NK cell mediated cytotoxicity|susceptibility to NK cell mediated cell killing|susceptibility to natural killer cell mediated cell death|susceptibility to natural killer cell mediated cytolysis|susceptibility to NK cell mediated cytolysis					Note that this term is intended for cell-surface molecules on a target cell which interact with activating receptors on a natural killer cell to promote natural killer cell mediated cytotoxicity.								biological_process											owl:Class	
GO:0000010	biolink:NamedThing	trans-hexaprenyltranstransferase activity	Catalysis of the reaction: all-trans-hexaprenyl diphosphate + isopentenyl diphosphate = all-trans-heptaprenyl diphosphate + diphosphate.	tmpzr1t_l9r_go_relaxed.owl					RHEA:20836									molecular_function											owl:Class	
GO:0050616	biolink:NamedThing	secologanin synthase activity	Catalysis of the reaction: loganin + NADPH + H+ + O2 = secologanin + NADP+ + 2 H2O.	tmpzr1t_l9r_go_relaxed.owl	loganin:oxygen oxidoreductase (ring-cleaving)				EC:1.14.19.62|MetaCyc:1.3.3.9-RXN|RHEA:20585									molecular_function											owl:Class	
GO:0031027	biolink:NamedThing	glutamate synthase complex (NADH)	A protein complex that in yeast consists of a large and a small subunit. Possesses glutamate synthase (NADH) activity.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0018572	biolink:NamedThing	3,5-dichlorocatechol 1,2-dioxygenase activity	Catalysis of the reaction: 3,5-dichlorocatechol + O2 = 2 H+ + 2,4-dichloro-cis,cis-muconate.	tmpzr1t_l9r_go_relaxed.owl					EC:1.13.11.-|UM-BBD_reactionID:r0276									molecular_function											owl:Class	
GO:0047059	biolink:NamedThing	polyvinyl alcohol dehydrogenase (cytochrome) activity	Catalysis of the reaction: polyvinyl alcohol + ferricytochrome c = oxidized polyvinyl alcohol + ferrocytochrome c + H+.	tmpzr1t_l9r_go_relaxed.owl	polyvinyl-alcohol:acceptor oxidoreductase activity|PVA dehydrogenase activity|polyvinyl-alcohol:(acceptor) oxidoreductase activity|polyvinyl alcohol:ferricytochrome-c oxidoreductase activity				RHEA:20157|MetaCyc:RXN-11316|KEGG_REACTION:R03136|EC:1.1.2.6	Formerly EC:1.1.99.23.								molecular_function											owl:Class	
GO:0018802	biolink:NamedThing	2,4-dihydroxyhept-2-ene-1,7-dioate aldolase activity	Catalysis of the reaction: 2,4-dihydroxy-hept-trans-2-ene-1,7-dioate = pyruvate + succinic semialdehyde.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0370									molecular_function											owl:Class	
GO:0047053	biolink:NamedThing	(S)-cheilanthifoline synthase activity	Catalysis of the reaction: (S)-scoulerine + [reduced NADPH--hemoprotein reductase] + O2 -> (S)-cheilanthifoline + [oxidized NADPH--hemoprotein reductase] + 2 H2O.	tmpzr1t_l9r_go_relaxed.owl	(S)-scoulerine oxidase (methylenedioxy-bridge-forming) activity|(S)-scoulerine,NADPH:oxygen oxidoreductase (methylenedioxy-bridge-forming)	https://github.com/geneontology/go-ontology/issues/21133			MetaCyc:1.14.21.2-RXN|EC:1.14.19.65|RHEA:20485|KEGG_REACTION:R03834									molecular_function											owl:Class	
GO:0102244	biolink:NamedThing	3-aminopropanal dehydrogenase activity	Catalysis of the reaction: 3-ammoniopropanal + NAD + H2O <=> 2 H+ + beta-alanine  + NADH.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-12332									molecular_function											owl:Class	
GO:0045728	biolink:NamedThing	respiratory burst after phagocytosis	A phase of elevated metabolic activity, during which oxygen consumption increases, that occurs in neutrophils, monocytes, and macrophages shortly after phagocytosing material. An enhanced uptake of oxygen leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals, which play a part in microbiocidal activity.	tmpzr1t_l9r_go_relaxed.owl	oxidative burst after phagocytosis|metabolic burst after phagocytosis													biological_process											owl:Class	
GO:0050446	biolink:NamedThing	azobenzene reductase activity	Catalysis of the reaction: N,N-dimethyl-1,4-phenylenediamine + aniline + NADP+ = 4-(dimethylamino)azobenzene + NADPH + H+.	tmpzr1t_l9r_go_relaxed.owl	NADPH-dependent azoreductase activity|NC-reductase activity|N,N-dimethyl-4-phenylazoaniline azoreductase activity|NADPH:4-(dimethylamino)azobenzene oxidoreductase activity|p-dimethylaminoazobenzene azoreductase activity|azo-dye reductase activity|azoreductase activity|NADPH2-dependent azoreductase activity|N,N-dimethyl-1,4-phenylenediamine, aniline:NADP+ oxidoreductase activity|azo reductase activity|dimethylaminobenzene reductase activity|nicotinamide adenine dinucleotide (phosphate) azoreductase activity|dibromopropylaminophenylazobenzoic azoreductase activity|NAD(P)H:1-(4'-sulfophenylazo)-2-naphthol oxidoreductase activity|p-aminoazobenzene reductase activity|new coccine (NC)-reductase|orange II azoreductase activity|NADPH2:4-(dimethylamino)azobenzene oxidoreductase activity|orange I azoreductase activity|methyl red azoreductase activity|New coccine (NC)-reductase activity				RHEA:16269|MetaCyc:AZOBENZENE-REDUCTASE-RXN|EC:1.7.1.6|UM-BBD_reactionID:r0808									molecular_function											owl:Class	
GO:0071912	biolink:NamedThing	asynchronous neurotransmitter secretion	Release of neurotransmitter at the synapse that persists for tens to hundreds of milliseconds after action potential invasion.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-09-22T01:45:35Z					biological_process											owl:Class	
GO:0000408	biolink:NamedThing	EKC/KEOPS complex	A protein complex involved in t6A tRNA modification. For example, in Saccharomyces cerevisiae the complex contains Bud32p, Kae1p, Gon7p, Cgi121p, and Pcc1p.	tmpzr1t_l9r_go_relaxed.owl	endopeptidase-like kinase chromatin-associated protein complex|threonyl-carbamoly transferase complex|TCTC|kinase, putative endopeptidase and other proteins of small size protein complex|KEOPS/EKC complex					Originally proposed to be involved in transcription as well as promoting telomere uncapping and telomere elongation.								cellular_component											owl:Class	
GO:0047168	biolink:NamedThing	isocitrate O-dihydroxycinnamoyltransferase activity	Catalysis of the reaction: caffeoyl-CoA + isocitrate = 2-caffeoylisocitrate + CoA.	tmpzr1t_l9r_go_relaxed.owl	caffeoyl-CoA:isocitrate 3-O-(3,4-dihydroxycinnamoyl)transferase activity				MetaCyc:2.3.1.126-RXN|EC:2.3.1.126|RHEA:20756|KEGG_REACTION:R01946									molecular_function											owl:Class	
GO:0050484	biolink:NamedThing	GMP 5'-nucleotidase activity	Catalysis of the reaction: 5'-GMP + H2O = guanosine + phosphate.	tmpzr1t_l9r_go_relaxed.owl	GMP 5' nucleotidase activity|IMP-GMP specific 5'-nucleotidase activity				MetaCyc:RXN-7609|RHEA:27714									molecular_function											owl:Class	
GO:0051980	biolink:NamedThing	iron-nicotianamine transmembrane transporter activity	Enables the transfer of the iron chelate iron-nicotianamine (Fe-NA) from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	Fe-NA chelate transporter activity													molecular_function											owl:Class	
GO:0000791	biolink:NamedThing	euchromatin	A dispersed and relatively uncompacted form of chromatin.	tmpzr1t_l9r_go_relaxed.owl	nuclear euchromatin				NIF_Subcellular:sao445485807|Wikipedia:Euchromatin							GO:0005719		cellular_component											owl:Class	
GO:0009376	biolink:NamedThing	HslUV protease complex	A protein complex that possesses ATP-dependent protease activity; consists of an ATPase large subunit with homology to other ClpX family ATPases and a peptidase small subunit related to the proteasomal beta-subunits of eukaryotes. In the E. coli complex, a double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer.	tmpzr1t_l9r_go_relaxed.owl	ClpYQ protease complex													cellular_component											owl:Class	
GO:0033281	biolink:NamedThing	TAT protein transport complex	A complex of three proteins integral to the cytoplasmic membrane of bacteria and membranes of organelles derived from bacteria (chloroplasts and mitochondria) involved in membrane transport of folded proteins.	tmpzr1t_l9r_go_relaxed.owl	TAT protein secretion complex|Twin-arginine translocation complex|TAT protein translocation system complex													cellular_component											owl:Class	
GO:0031013	biolink:NamedThing	troponin I binding	Binding to troponin I, the inhibitory subunit of the troponin complex.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1901498	biolink:NamedThing	response to tetralin	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tetralin stimulus.	tmpzr1t_l9r_go_relaxed.owl								tt	2012-10-16T15:10:22Z					biological_process											owl:Class	
GO:0050181	biolink:NamedThing	phorbol-diester hydrolase activity	Catalysis of the reaction: H(2)O + phorbol 12,13-dibutanoate = butanoate + H(+) + phorbol 13-butanoate.	tmpzr1t_l9r_go_relaxed.owl	phorbol-12,13-diester 12-ester hydrolase activity|PDEH|12,13-diacylphorbate 12-acylhydrolase activity|diacylphorbate 12-hydrolase activity				EC:3.1.1.51|KEGG_REACTION:R04119|MetaCyc:PHORBOL-DIESTER-HYDROLASE-RXN|RHEA:21316									molecular_function											owl:Class	
GO:0031085	biolink:NamedThing	BLOC-3 complex	A protein complex required for the biogenesis of specialized organelles of the endosomal-lysosomal system, such as melanosomes and platelet dense granules. The human complex contains the Hps1 and Hps4 proteins.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0034301	biolink:NamedThing	endospore formation	The process in which a cell gives rise to an endospore, a dormant, highly resistant spore with a thick wall that forms within the mother cell. Endospores are produced by some low G+C Gram-positive bacteria in response to harsh conditions.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0018563	biolink:NamedThing	2,3-dihydroxy-ethylbenzene 1,2-dioxygenase activity	Catalysis of the reaction: 2,3-dihydroxyethylbenzene + O2 = H+ + 2-hydroxy-6-oxoocta-2,4-dienoate.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0310|EC:1.13.11.-									molecular_function											owl:Class	
GO:0050392	biolink:NamedThing	vicianin beta-glucosidase activity	Catalysis of the reaction: (R)-vicianin + H(2)O = mandelonitrile + vicianose.	tmpzr1t_l9r_go_relaxed.owl	vicianin b-glucosidase activity|(R)-vicianin beta-D-glucohydrolase activity|vicianin hydrolase activity				EC:3.2.1.119|KEGG_REACTION:R03642|MetaCyc:VICIANIN-BETA-GLUCOSIDASE-RXN|RHEA:14041									molecular_function											owl:Class	
GO:1905054	biolink:NamedThing	calcium-induced calcium release activity involved in regulation of presynaptic cytosolic calcium ion concentration	Any calcium-induced calcium release activity that is involved in regulation of presynaptic cytosolic calcium ion concentration.	tmpzr1t_l9r_go_relaxed.owl	calcium-induced calcium release activity involved in regulation of presynaptic cytosolic calcium levels							dos	2016-03-17T12:12:53Z					molecular_function											owl:Class	
GO:0038143	biolink:NamedThing	ERBB3:ERBB2 complex	A heterodimeric complex between the tyrosine kinase receptor ERBB2 and a ligand-activated receptor ERBB3. ERBB2, which does not bind any known ligand, is activated through formation of a heterodimer with another ligand-activated ERBB family member such as ERBB3.	tmpzr1t_l9r_go_relaxed.owl	EGFR:ERBB2 heterodimer|NRG1/2:ERBB3:ERBB2							bf	2012-03-30T02:16:56Z					cellular_component											owl:Class	
GO:0035750	biolink:NamedThing	protein localization to myelin sheath abaxonal region	Any process in which a protein is transported to, and/or maintained in, the abaxonal region of the myelin sheath. The abaxonal region is the region of the myelin sheath furthest from the axon.	tmpzr1t_l9r_go_relaxed.owl	protein localisation to myelin sheath abaxonal region							bf	2011-03-23T10:20:06Z					biological_process											owl:Class	
GO:0007207	biolink:NamedThing	phospholipase C-activating G protein-coupled acetylcholine receptor signaling pathway	The series of molecular signals generated as a consequence of a G protein-coupled acetylcholine receptor binding to its physiological ligand, where the pathway proceeds with activation of phospholipase C (PLC) and a subsequent release of inositol trisphosphate (IP3) and diacylglycerol (DAG).	tmpzr1t_l9r_go_relaxed.owl	activation of phospholipase C activity by G-protein coupled acetylcholine receptor signaling pathway|muscarinic receptor signaling pathway via activation of PLC|phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway|activation of phospholipase C activity by muscarinic acetylcholine receptor signaling pathway|activation of phospholipase C activity by muscarinic acetylcholine receptor signalling pathway|muscarinic acetylcholine receptor, phospholipase C activating pathway													biological_process											owl:Class	
GO:0048510	biolink:NamedThing	regulation of timing of transition from vegetative to reproductive phase	The process controlling the point in time during development when a vegetative meristem will change its identity to become an inflorescence or floral meristem, and/or the rate at which the change occurs.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0032358	biolink:NamedThing	oxidized pyrimidine DNA binding	Binding to a DNA region containing an oxidized pyrimidine residue.	tmpzr1t_l9r_go_relaxed.owl	oxidized pyrimidine base DNA binding|oxidized pyrimidine nucleobase DNA binding|oxidised pyrimidine DNA binding													molecular_function											owl:Class	
GO:0050491	biolink:NamedThing	sulcatone reductase activity	Catalysis of the reaction: NAD(+) + sulcatol = H(+) + NADH + sulcatone.	tmpzr1t_l9r_go_relaxed.owl	sulcatol:NAD+ oxidoreductase activity				RHEA:24484|EC:1.1.1.260|MetaCyc:1.1.1.260-RXN|KEGG_REACTION:R05678									molecular_function											owl:Class	
GO:0019423	biolink:NamedThing	sulfur oxidation, ferric ion-dependent	A sulfur oxidation process that proceeds via the reaction catalyzed by sulfur:ferric ion oxidoreductase, and requires the presence of ferric ion (Fe3+).	tmpzr1t_l9r_go_relaxed.owl	sulphur oxidation, ferric ion-dependent				MetaCyc:FESULFOX-PWY									biological_process											owl:Class	
GO:0004044	biolink:NamedThing	amidophosphoribosyltransferase activity	Catalysis of the reaction: 5-phospho-beta-D-ribosylamine + L-glutamate + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + L-glutamine + H(2)O.	tmpzr1t_l9r_go_relaxed.owl	5'-phosphoribosylpyrophosphate amidotransferase activity|alpha-5-phosphoribosyl-1-pyrophosphate amidotransferase activity|glutamine phosphoribosylpyrophosphate amidotransferase activity|phosphoribosyldiphosphate 5-amidotransferase activity|5-phosphoribosylamine:diphosphate phospho-alpha-D-ribosyltransferase (glutamate-amidating)|phosphoribosylpyrophosphate glutamyl amidotransferase activity|5-phosphororibosyl-1-pyrophosphate amidotransferase activity|5-phosphoribosyl-1-pyrophosphate amidotransferase activity|glutamine phosphoribosyldiphosphate amidotransferase activity|phosphoribosyl pyrophosphate amidotransferase activity|phosphoribose pyrophosphate amidotransferase activity|glutamine ribosylpyrophosphate 5-phosphate amidotransferase activity|glutamine 5-phosphoribosylpyrophosphate amidotransferase activity				MetaCyc:PRPPAMIDOTRANS-RXN|EC:2.4.2.14|RHEA:14905|Reactome:R-HSA-73815|KEGG_REACTION:R01072									molecular_function											owl:Class	
GO:0004636	biolink:NamedThing	phosphoribosyl-ATP diphosphatase activity	Catalysis of the reaction: 1-(5-phospho-D-ribosyl)-ATP + H(2)O = 1-(5-phosphonatoribosyl)-5'-AMP + diphosphate + H(+).	tmpzr1t_l9r_go_relaxed.owl	1-(5-phosphoribosyl)-ATP diphosphohydrolase activity|phosphoribosyl-ATP pyrophosphatase activity|phosphoribosyladenosine triphosphate pyrophosphatase activity				MetaCyc:HISTPRATPHYD-RXN|KEGG_REACTION:R04035|EC:3.6.1.31|RHEA:22828									molecular_function											owl:Class	
GO:0034005	biolink:NamedThing	germacrene-A synthase activity	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = (+)-(R)-germacrene A + diphosphate.	tmpzr1t_l9r_go_relaxed.owl	(+)-(10R)-germacrene A synthase activity|2-trans,6-trans-farnesyl-diphosphate diphosphate-lyase (germacrene-A-forming) activity|2-trans,6-trans-farnesyl-diphosphate diphosphate-lyase [(+)-germacrene-A-forming] activity|germacrene A synthase activity|GAS|(+)-germacrene A synthase activity				RHEA:12516|KEGG_REACTION:R07649|MetaCyc:4.2.3.23-RXN|EC:4.2.3.23									molecular_function											owl:Class	
GO:0000417	biolink:NamedThing	HIR complex	A protein complex proposed to be involved in replication-independent nucleosome assembly, by promoting histone deposition onto DNA. For example, in Saccharomyces, the complex contains Hir1p, Hir2p, Hir3p, and Hpc2p.	tmpzr1t_l9r_go_relaxed.owl	HIRA complex													cellular_component											owl:Class	
GO:0039615	biolink:NamedThing	T=1 icosahedral viral capsid	The protein coat that surrounds the infective nucleic acid in some virus particles where the subunits (capsomeres) are arranged to form an icosahedron with T=1 symmetry. The T=1 capsid is composed of 12 pentameric capsomeres.	tmpzr1t_l9r_go_relaxed.owl					VZ:1057			bf	2012-07-18T01:46:17Z					cellular_component											owl:Class	
GO:0008994	biolink:NamedThing	rhamnulose-1-phosphate aldolase activity	Catalysis of the reaction: L-rhamnulose 1-phosphate = glycerone phosphate + (S)-lactaldehyde.	tmpzr1t_l9r_go_relaxed.owl	L-rhamnulose 1-phosphate aldolase activity|rhamnulose phosphate aldolase activity|L-rhamnulose-phosphate aldolase activity|L-rhamnulose-1-phosphate lactaldehyde-lyase activity|L-rhamnulose-1-phosphate S-lactaldehyde-lyase (glycerone-phosphate-forming)				EC:4.1.2.19|RHEA:19689|MetaCyc:RHAMNULPALDOL-RXN									molecular_function											owl:Class	
GO:0044674	biolink:NamedThing	methyl coenzyme M reductase complex	A hexameric complex consisting of three polypeptides in an alpha2beta2gamma2 arrangement. Involved in the reduction of the coenzyme M-bound methyl group to methane, which is the final step in methanogenesis.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-08-09T10:52:33Z					cellular_component											owl:Class	
GO:0110010	biolink:NamedThing	basolateral protein secretion	The controlled release of proteins from a cell at the sides which interface adjacent cells and near the base.	tmpzr1t_l9r_go_relaxed.owl								kmv						biological_process											owl:Class	
GO:0047569	biolink:NamedThing	3-oxoadipate CoA-transferase activity	Catalysis of the reaction: succinyl-CoA + 3-oxoadipate = succinate + 3-oxoadipyl-CoA.	tmpzr1t_l9r_go_relaxed.owl	3-oxoadipate succinyl-CoA transferase activity|3-oxoadipate coenzyme A-transferase activity|succinyl-CoA:3-oxoadipate CoA-transferase activity|beta-ketoadipate:succinyl-CoA transferase activity				UM-BBD_reactionID:r1050|RHEA:12048|EC:2.8.3.6|MetaCyc:3-OXOADIPATE-COA-TRANSFERASE-RXN									molecular_function											owl:Class	
GO:0071872	biolink:NamedThing	cellular response to epinephrine stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an epinephrine stimulus. Epinephrine is a catecholamine that has the formula C9H13NO3; it is secreted by the adrenal medulla to act as a hormone, and released by certain neurons to act as a neurotransmitter active in the central nervous system.	tmpzr1t_l9r_go_relaxed.owl	cellular response to adrenaline stimulus					Note that epinephrine and norepinephrine are ligands for the same receptors, and there are multiple adrenergic receptors.		mah	2010-09-13T03:31:40Z					biological_process											owl:Class	
GO:0045483	biolink:NamedThing	aristolochene synthase activity	Catalysis of the reaction: trans,trans-farnesyl diphosphate = aristolochene + diphosphate.	tmpzr1t_l9r_go_relaxed.owl	trans,trans-farnesyl diphosphate aristolochene-lyase activity|trans,trans-farnesyl-diphosphate diphosphate-lyase (cyclizing, aristolochene-forming)|2-trans,6-trans-farnesyl-diphosphate diphosphate-lyase (cyclizing, aristolochene-forming)|sesquiterpene cyclase activity				EC:4.2.3.9|RHEA:19825|MetaCyc:ARISTOLOCHENE-SYNTHASE-RXN									molecular_function											owl:Class	
GO:0046428	biolink:NamedThing	1,4-dihydroxy-2-naphthoate octaprenyltransferase activity	Catalysis of the reaction: 1,4-dihydroxy-2-naphthoate + polyprenylpyrophosphate = dimethylmenaquinone + diphosphate + CO2.	tmpzr1t_l9r_go_relaxed.owl	1,4-Dihydroxy-2-naphtoate prenyltransferase activity				EC:2.5.1.74|RHEA:30099|MetaCyc:DMK-RXN									molecular_function											owl:Class	
GO:0019151	biolink:NamedThing	galactose 1-dehydrogenase activity	Catalysis of the reaction: D-galactose + NAD+ = D-galactono-1,4-lactone + NADH + H+.	tmpzr1t_l9r_go_relaxed.owl	D-galactose:NAD+ 1-oxidoreductase activity|NAD-dependent D-galactose dehydrogenase activity|beta-galactose dehydrogenase activity|D-galactose 1-dehydrogenase activity|D-galactose dehydrogenase activity				EC:1.1.1.48|MetaCyc:GALACTODEHYDROG-RXN|RHEA:21296									molecular_function											owl:Class	
GO:0097348	biolink:NamedThing	host cell endocytic vesicle membrane	The lipid bilayer surrounding a host cell endocytic vesicle.	tmpzr1t_l9r_go_relaxed.owl								pr	2012-06-25T10:31:34Z					cellular_component											owl:Class	
GO:0071100	biolink:NamedThing	alphaV-beta8 integrin-MMP14-TGFbeta-1 complex	A protein complex that consists of an alphaV-beta8 integrin complex bound to matrix metalloproteinase 14 and transforming growth factor beta-1 (TGFbeta-1).	tmpzr1t_l9r_go_relaxed.owl	ITGAV-ITGB8-MMP14-TGFB1 complex							mah	2009-11-06T04:52:43Z					cellular_component											owl:Class	
GO:1904493	biolink:NamedThing	tetrahydrofolyl-poly(glutamate) polymer binding	Binding to tetrahydrofolyl-poly(glutamate) polymer.	tmpzr1t_l9r_go_relaxed.owl								hal	2015-07-20T10:34:28Z					molecular_function											owl:Class	
GO:0070287	biolink:NamedThing	ferritin receptor activity	Combining with ferritin, and delivering ferritin into the cell via endocytosis.	tmpzr1t_l9r_go_relaxed.owl	ferritin complex receptor activity													molecular_function											owl:Class	
GO:0017084	biolink:NamedThing	delta1-pyrroline-5-carboxylate synthetase activity	Catalysis of the reaction: L-glutamate + ATP + NADPH = ADP + L-glutamate gamma-semialdehyde + NADP+ + phosphate.	tmpzr1t_l9r_go_relaxed.owl	D1-pyrroline-5-carboxylate synthetase activity				Reactome:R-HSA-508040|RHEA:33207									molecular_function											owl:Class	
GO:0102740	biolink:NamedThing	theobromine:S-adenosyl-L-methionine 1-N-methyltransferase activity	Catalysis of the reaction: theobromine + S-adenosyl-L-methionine  <=> H+ + caffeine + S-adenosyl-L-homocysteine.	tmpzr1t_l9r_go_relaxed.owl					RHEA:20944|EC:2.1.1.160|MetaCyc:RXN-7599									molecular_function											owl:Class	
GO:0038142	biolink:NamedThing	EGFR:ERBB2 complex	A heterodimeric complex between the tyrosine kinase receptor ERBB2 and a ligand-activated epidermal growth factor receptor (EGFR/ERBB1). ERBB2, which does not bind any known ligand, is activated through formation of a heterodimer with another ligand-activated ERBB family member such as EGFR.	tmpzr1t_l9r_go_relaxed.owl	EGFR:ERBB2 heterodimer|EGF:EGFR:ERBB2 complex							bf	2012-03-30T02:10:38Z					cellular_component											owl:Class	
GO:0030411	biolink:NamedThing	scytalone dehydratase activity	Catalysis of the reaction: scytalone = 1,3,8-trihydroxynaphthalene + H(2)O.	tmpzr1t_l9r_go_relaxed.owl	scytalone 7,8-hydro-lyase (1,3,8-trihydroxynaphthalene-forming)|scytalone 7,8-hydro-lyase activity				KEGG_REACTION:R02907|RHEA:24396|MetaCyc:SCYTALONE-DEHYDRATASE-RXN|EC:4.2.1.94									molecular_function											owl:Class	
GO:0097162	biolink:NamedThing	MADS box domain binding	Binding to a MADS box domain, a protein domain that encodes the DNA-binding MADS domain. The MADS domain binds to DNA sequences of high similarity to the motif CC[A/T]6GG termed the CArG-box. MADS-domain proteins are generally transcription factors. The length of the MADS-box is in the range of 168 to 180 base pairs.	tmpzr1t_l9r_go_relaxed.owl								pr	2011-09-27T10:10:59Z					molecular_function											owl:Class	
GO:0102043	biolink:NamedThing	isopentenyl phosphate kinase activity	Catalysis of the reaction: isopentenyl phosphate(2-) + ATP(4-) <=> isopentenyl diphosphate(3-) + ADP(3-).	tmpzr1t_l9r_go_relaxed.owl					RHEA:33963|MetaCyc:RXN-10068|EC:2.7.4.26									molecular_function											owl:Class	
GO:0016543	biolink:NamedThing	male courtship behavior, orientation prior to leg tapping and wing vibration	The process during courtship, where the male orients towards a potential partner. An example of this is found in Drosophila melanogaster.	tmpzr1t_l9r_go_relaxed.owl	male courtship behavior, orientation|male courtship behaviour, orientation|male courtship behaviour, orientation prior to leg tapping and wing vibration													biological_process											owl:Class	
GO:0018828	biolink:NamedThing	halohydrin hydrogen-halide-lyase A activity	Catalysis of the elimination of HCl from a chloro- or bromopropanol, yielding an epoxypropane.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_enzymeID:e0048									molecular_function											owl:Class	
GO:0047397	biolink:NamedThing	dolichylphosphate-glucose phosphodiesterase activity	Catalysis of the reaction: dolichyl beta-D-glucosyl phosphate + H2O = dolichol-phosphate + beta-D-glucose.	tmpzr1t_l9r_go_relaxed.owl	dolichol phosphoglucose phosphodiesterase activity|dolichyl-phosphate-glucose phosphodiesterase activity|Dol-P-Glc phosphodiesterase activity|dolichyl-beta-D-glucosyl-phosphate dolichylphosphohydrolase activity				MetaCyc:3.1.4.48-RXN|RHEA:13857|EC:3.1.4.48									molecular_function											owl:Class	
GO:0106264	biolink:NamedThing	protein serine kinase activity (using GTP as donor)	Catalysis of the reactions: GTP + L-seryl-[protein] = GDP + H(+) + O-phospho-L-seryl-[protein].	tmpzr1t_l9r_go_relaxed.owl					RHEA:64020			hjd	2020-05-28T18:51:18Z					molecular_function											owl:Class	
GO:0044082	biolink:NamedThing	modulation by symbiont of host small GTPase mediated signal transduction	Any process in which a symbiont organism modulates the frequency, rate or extent of small GTPase mediated signal transduction in its host organism.	tmpzr1t_l9r_go_relaxed.owl	regulation by symbiont of host small GTPase mediated signal transduction|modulation of host small GTPase mediated signal transduction by symbiont													biological_process											owl:Class	
GO:0005112	biolink:NamedThing	Notch binding	Binding to a Notch (N) protein, a surface receptor.	tmpzr1t_l9r_go_relaxed.owl	Notch ligand|Notch receptor binding|N ligand|N binding													molecular_function											owl:Class	
GO:0102501	biolink:NamedThing	D-fructuronate reductase activity	Catalysis of the reaction: D-mannonate + NADP = NADPH + H+ + D-fructuronate.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-14368									molecular_function											owl:Class	
GO:0022886	biolink:NamedThing	channel-forming ionophore activity	Enables transport of a solute across a membrane. This kind of transporter interacts much more weakly with the solute than the carrier does. It is an aqueous pore that extends across the membrane. It may change from closed to open and back. It transports faster than a carrier. It is always passive.	tmpzr1t_l9r_go_relaxed.owl	ionophore activity													molecular_function											owl:Class	
GO:0061202	biolink:NamedThing	clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane	The lipid bilayer surrounding a clathrin-sculpted gamma-aminobutyric acid transport vesicle.	tmpzr1t_l9r_go_relaxed.owl	clathrin sculpted gamma-aminobutyric acid transport vesicle membrane|clathrin sculpted GABA transport vesicle membrane							dph	2010-07-29T10:54:33Z					cellular_component											owl:Class	
GO:0021524	biolink:NamedThing	visceral motor neuron differentiation	The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of visceral motor neurons. Visceral motor neurons innervate glandular targets and are responsible for transmission of motor impulses from the brain to the periphery. Differentiation includes the processes involved in commitment of a cell to a specific fate.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0033556	biolink:NamedThing	dolichyl pyrophosphate Man7GlcNAc2 alpha-1,3-glucosyltransferase activity	Catalysis of the addition of a glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation; the transfer of glucose from dolichyl phosphate glucose (Dol-P-Glc) on to the lipid-linked oligosaccharide Man(7)GlcNAc(2)-PP-Dol.	tmpzr1t_l9r_go_relaxed.owl	dolichyl-P-Glc:Man7GlcNAc2-PP-dolichyl glucosyltransferase activity													molecular_function											owl:Class	
GO:0140090	biolink:NamedThing	membrane curvature sensor activity	Preferential binding of proteins on curved membranes. The binding to curved membranes by insertion (aka wedging) to curved membranes is mediated by both the hydrophobic and hydrophilic faces of the helix of membrane curvature sensing (MCS) proteins.	tmpzr1t_l9r_go_relaxed.owl								pg	2017-08-19T20:37:54Z					molecular_function											owl:Class	
GO:0016250	biolink:NamedThing	N-sulfoglucosamine sulfohydrolase activity	Catalysis of the reaction: N-sulfo-D-glucosamine + H2O = D-glucosamine + sulfate.	tmpzr1t_l9r_go_relaxed.owl	sulfoglucosamine sulfamidase activity|N-sulfo-D-glucosamine sulfohydrolase activity|2-desoxy-D-glucoside-2-sulphamate sulphohydrolase (sulphamate sulphohydrolase)|heparin sulfamidase activity|sulphamidase activity|N-sulphoglucosamine sulphohydrolase activity				RHEA:17881|Reactome:R-HSA-2263444|Reactome:R-HSA-2090043|MetaCyc:N-SULFOGLUCOSAMINE-SULFOHYDROLASE-RXN|EC:3.10.1.1|Reactome:R-HSA-1678708|Reactome:R-HSA-9036050									molecular_function											owl:Class	
GO:0016826	biolink:NamedThing	hydrolase activity, acting on acid sulfur-nitrogen bonds	Catalysis of the hydrolysis of any acid sulfur-nitrogen bond.	tmpzr1t_l9r_go_relaxed.owl	hydrolase activity, acting on acid sulphur-nitrogen bonds				EC:3.10.-.-									molecular_function											owl:Class	
GO:0004824	biolink:NamedThing	lysine-tRNA ligase activity	Catalysis of the reaction: ATP + L-lysine + tRNA(Lys) = AMP + diphosphate + L-lysyl-tRNA(Lys).	tmpzr1t_l9r_go_relaxed.owl	lysyl-transfer ribonucleate synthetase activity|L-lysine-transfer RNA ligase activity|lysyl-transfer RNA synthetase activity|lysine-tRNA synthetase activity|lysyl-tRNA synthetase activity|L-lysine:tRNALys ligase (AMP-forming)|lysine translase activity				EC:6.1.1.6|Reactome:R-HSA-380233|MetaCyc:LYSINE--TRNA-LIGASE-RXN|RHEA:20792|Reactome:R-HSA-380008									molecular_function											owl:Class	
GO:0001962	biolink:NamedThing	alpha-1,3-galactosyltransferase activity	Catalysis of the transfer of a galactose residue from a donor molecule, such as GDP-galactose or UDP-galactose, to an oligosaccharide, forming an alpha-(1->3) linkage.	tmpzr1t_l9r_go_relaxed.owl	isoglobotriaosylceramide synthase													molecular_function											owl:Class	
GO:0034808	biolink:NamedThing	benzo(a)pyrene 4,5-dioxygenase activity	Catalysis of the reaction: benzo(a)pyrene + O2 = benzo(a)pyrene-cis-4,5-dihydrodiol.	tmpzr1t_l9r_go_relaxed.owl					EC:1.13.11.-|UM-BBD_reactionID:r1126									molecular_function											owl:Class	
GO:0071528	biolink:NamedThing	tRNA re-export from nucleus	The directed movement from the nucleus to the cytoplasm of a tRNA that was previously exported to the cytoplasm and then imported back into the nucleus. The processes of primary tRNA export and secondary export (re-export) can be distinguished because in organisms in which tRNA splicing occurs in the cytoplasm, the export of a mature tRNA must occur by re-export.	tmpzr1t_l9r_go_relaxed.owl	tRNA reexport from nucleus							mah	2010-01-07T04:17:05Z					biological_process											owl:Class	
GO:0060361	biolink:NamedThing	flight	Self-propelled movement of an organism from one location to another through the air, usually by means of active wing movement.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0014814	biolink:NamedThing	axon regeneration at neuromuscular junction	The regrowth of axons following their loss or damage at the neuromuscular junction. Motor axons regenerate after injury and they form neuro-muscular junctions with skeletal myofibers similar to normal ones.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0051911	biolink:NamedThing	Methanosarcina-phenazine hydrogenase activity	Catalysis of the reaction: H2 + 2-(2,3-dihydropentaprenyloxy)phenazine = 2-dihydropentaprenyloxyphenazine.	tmpzr1t_l9r_go_relaxed.owl	methylviologen-reducing hydrogenase activity|hydrogen:2-(2,3-dihydropentaprenyloxy)phenazine oxidoreductase activity|coenzyme-M-7-mercaptoheptanoylthreonine-phosphate-heterodisulfide hydrogenase activity|methanophenazine hydrogenase activity				RHEA:24436|MetaCyc:RXN-7733|EC:1.12.98.3									molecular_function											owl:Class	
GO:0008766	biolink:NamedThing	UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity	Catalysis of the reaction: ATP + UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminoheptanedioate + D-alanyl-D-alanine = ADP + phosphate + UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-6-carboxy-L-lysyl-D-alanyl-D-alanine.	tmpzr1t_l9r_go_relaxed.owl					EC:6.3.2.10|RHEA:28374|MetaCyc:UDP-NACMURALGLDAPAALIG-RXN	Note that EC:6.3.2.15 was deleted from EC as the reaction is performed by UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase (EC:6.3.2.10).								molecular_function											owl:Class	
GO:0072629	biolink:NamedThing	interleukin-28B production	The appearance of interleukin-28B due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	tmpzr1t_l9r_go_relaxed.owl	IL28B production|interleukin-28B secretion|interferon lambda 3 production|IL-28B production					Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.						GO:0072630		biological_process											owl:Class	
GO:1903699	biolink:NamedThing	tarsal gland development	The process whose specific outcome is the progression of a tarsal gland over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl	tarsoconjunctival gland development|glandula tarsales development|gland of Meibom development|Meibomian gland development							cls	2014-12-03T11:47:07Z					biological_process											owl:Class	
GO:0034291	biolink:NamedThing	canonical holin activity	A compound function consisting of the regulated formation of a pore via oligomerisation of an existing pool of subunits in the plasma membrane.  The resulting channel activity directly allows release of a fully-folded phage-encoded endolysin (murein-degradase) from the cell.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0102705	biolink:NamedThing	serine decarboxylase activity	Catalysis of the reaction: H+ + L-serine  <=> ethanolaminium(1+) + carbon dioxide.	tmpzr1t_l9r_go_relaxed.owl					RHEA:45824|MetaCyc:RXN-5641									molecular_function											owl:Class	
GO:0019126	biolink:NamedThing	peptidyl-serine racemization	The racemization of peptidyl-serine.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0195							GO:0018372|GO:0018090		biological_process											owl:Class	
GO:0009115	biolink:NamedThing	xanthine catabolic process	The chemical reactions and pathways resulting in the breakdown of xanthine, 2,6-dihydroxypurine, a purine formed in the metabolic breakdown of guanine but not present in nucleic acids.	tmpzr1t_l9r_go_relaxed.owl	xanthine catabolism|xanthine oxidation|xanthine breakdown|xanthine degradation											GO:0006151		biological_process											owl:Class	
GO:0003262	biolink:NamedThing	endocardial progenitor cell migration to the midline involved in heart field formation	The orderly movement of an endocardial progenitor cell toward the midline to form the heart field. Cardiac muscle progenitor cells are non-terminally differentiated, mesoderm-derived cells that are committed to differentiate into endocardial cells of the heart.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-10-15T02:00:41Z					biological_process											owl:Class	
GO:0005540	biolink:NamedThing	hyaluronic acid binding	Binding to hyaluronic acid, a polymer composed of repeating dimeric units of glucuronic acid and N-acetyl glucosamine.	tmpzr1t_l9r_go_relaxed.owl	hyaluronan binding													molecular_function											owl:Class	
GO:0008083	biolink:NamedThing	growth factor activity	The function that stimulates a cell to grow or proliferate. Most growth factors have other actions besides the induction of cell growth or proliferation.	tmpzr1t_l9r_go_relaxed.owl						Also consider annotating to 'receptor agonist activity ; GO:0048018'.								molecular_function											owl:Class	
GO:0050393	biolink:NamedThing	vinylacetyl-CoA delta-isomerase activity	Catalysis of the reaction: vinylacetyl-CoA = crotonoyl-CoA.	tmpzr1t_l9r_go_relaxed.owl	vinylacetyl coenzyme A isomerase activity|delta3-cis-delta2-trans-enoyl-CoA isomerase|vinylacetyl-CoA D-isomerase activity|vinylacetyl-CoA delta3-delta2-isomerase activity|vinylacetyl coenzyme A delta-isomerase activity				EC:5.3.3.3|KEGG_REACTION:R03031|MetaCyc:VINYLACETYL-COA-DELTA-ISOMERASE-RXN|RHEA:10572									molecular_function											owl:Class	
GO:0050834	biolink:NamedThing	molybdenum incorporation via L-cysteinyl copper sulfido molybdopterin cytosine dinucleotide	The incorporation of molybdenum into a protein by L-cysteinyl copper sulfido molybdopterin cytosine dinucleotide.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0355									biological_process											owl:Class	
GO:0010306	biolink:NamedThing	rhamnogalacturonan II biosynthetic process	The chemical reactions and pathways resulting in the formation of rhamnogalacturonan II, a low molecular mass (5 - 10KDa) pectic polysaccharide, conserved in the primary walls of dicotyledenous and monocotyledenous plants and gymnosperms.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0070531	biolink:NamedThing	BRCA1-A complex	A protein complex that contains the BRCA1-BARD1 heterodimer, RAP80/UIMC1, BRCC3/BRCC36, BRE/BRCC45, FAM175A/CCDC98/Abraxas and MERIT40/NBA1, and specifically recognizes and binds K63-linked polyubiquitin chains present on histone H2A and H2AX at DNA damage sites.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0018773	biolink:NamedThing	acetylpyruvate hydrolase activity	Catalysis of the reaction: acetylpyruvate + H(2)O = acetate + H(+) + pyruvate.	tmpzr1t_l9r_go_relaxed.owl	2,4-dioxopentanoate acetylhydrolase activity				MetaCyc:ACETYLPYRUVATE-HYDROLASE-RXN|KEGG_REACTION:R00324|RHEA:16097|UM-BBD_reactionID:r0095|EC:3.7.1.6									molecular_function											owl:Class	
GO:0097182	biolink:NamedThing	protein C inhibitor-coagulation factor Xa complex	A heterodimeric protein complex that contains protein C inhibitor (SERPINA5) and coagulation factor Xa (F10); formation of the complex inhibits the serine protease activity of coagulation factor Xa.	tmpzr1t_l9r_go_relaxed.owl	SERPINA5-coagulation factor Xa complex|serpin A5-coagulation factor Xa complex|PCI-coagulation factor Xa complex|plasma serine protease inhibitor-coagulation factor Xa complex							pr	2011-10-16T09:01:29Z					cellular_component											owl:Class	
GO:0043920	biolink:NamedThing	aminopropylagmatine ureohydrolase activity	Catalysis of the reaction: N1-aminopropylagmatine + H2O = spermidine + urea.	tmpzr1t_l9r_go_relaxed.owl					EC:3.5.3.24|RHEA:35827									molecular_function											owl:Class	
GO:0071087	biolink:NamedThing	alpha11-beta1 integrin-collagen type I complex	A protein complex that consists of an alpha11-beta1 integrin complex bound to a type I collagen.	tmpzr1t_l9r_go_relaxed.owl	ITGA11-ITGB1-COL1A1 complex							mah	2009-11-06T04:45:27Z					cellular_component											owl:Class	
GO:1990076	biolink:NamedThing	cell wall polysaccharide catabolic process involved in abscission	Any cell wall polysaccharide catabolic process that is involved in abscission.	tmpzr1t_l9r_go_relaxed.owl								dhl	2013-04-25T16:29:43Z					biological_process											owl:Class	
GO:0047152	biolink:NamedThing	methanol-5-hydroxybenzimidazolylcobamide Co-methyltransferase activity	Catalysis of the reaction: 5-hydroxybenzimidazolylcobamide + methanol = H2O + Co-methyl-Co-5-hydroxybenzimidazolylcob(I)amide.	tmpzr1t_l9r_go_relaxed.owl	MtaB|MT1|MT 1|methanol:corrinoid methyltransferase activity|methanol:5-hydroxybenzimidazolylcobamide Co-methyltransferase activity|methanol:5-hydroxybenzimidazolylcobamide methyltransferase activity|methanol-corrinoid protein Co-methyltransferase|methanol cobalamin methyltransferase activity|methyltransferase 1				RHEA:45204|MetaCyc:2.1.1.90-RXN|EC:2.1.1.90	This function is the first step in the pathway of methanogenesis from methanol.						GO:1990087		molecular_function											owl:Class	
GO:0102891	biolink:NamedThing	2'4'6'34-pentahydroxychalcone 4'-O-glucosyltransferase activity	Catalysis of the reaction: UDP-alpha-D-glucose + 2',3,4,4',6'-pentahydroxychalcone <=> H+ + 2',3,4,4',6'-pentahydroxychalcone 4'-O-beta-D-glucoside + UDP.	tmpzr1t_l9r_go_relaxed.owl					RHEA:34295|EC:2.4.1.286|MetaCyc:RXN-8455									molecular_function											owl:Class	
GO:0016544	biolink:NamedThing	male courtship behavior, tapping to detect pheromone	The process during courtship where the male insect taps the female with his frontal leg. An example of this is found in Drosophila melanogaster.	tmpzr1t_l9r_go_relaxed.owl	male courtship behavior, tapping|male courtship behaviour, tapping to detect pheromone|male courtship behaviour, tapping													biological_process											owl:Class	
GO:0140260	biolink:NamedThing	mitochondrial proton-transporting ATP synthase complex binding	Binding to a mitochondrial proton-transporting ATP synthase complex.	tmpzr1t_l9r_go_relaxed.owl								pg	2018-09-10T19:38:26Z					molecular_function											owl:Class	
GO:0047889	biolink:NamedThing	ferredoxin-nitrate reductase activity	Catalysis of the reaction: nitrite + H2O + 2 oxidized ferredoxin = nitrate + 2 reduced ferredoxin.	tmpzr1t_l9r_go_relaxed.owl	assimilatory nitrate reductase activity|nitrate (ferredoxin) reductase activity|nitrite:ferredoxin oxidoreductase activity|assimilatory ferredoxin-nitrate reductase activity				MetaCyc:1.7.7.2-RXN|RHEA:21828|EC:1.7.7.2									molecular_function											owl:Class	
GO:0031158	biolink:NamedThing	negative regulation of aggregate size involved in sorocarp development	Any process that decreases the size of the aggregate formed during sorocarp formation.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of aggregate size|down regulation of aggregate size|inhibition of aggregate size|downregulation of aggregate size													biological_process											owl:Class	
GO:0047803	biolink:NamedThing	cysteine lyase activity	Catalysis of the reaction: L-cysteine + sulfite = L-cysteate + sulfide.	tmpzr1t_l9r_go_relaxed.owl	L-cysteine hydrogen-sulfide-lyase (adding sulfite)|L-cysteine hydrogen-sulfide-lyase (adding sulfite; L-cysteate-forming)|cysteine (sulfite) lyase activity				EC:4.4.1.10|MetaCyc:CYSTEINE-LYASE-RXN|RHEA:20916									molecular_function											owl:Class	
GO:0047272	biolink:NamedThing	phosphopolyprenol glucosyltransferase activity	Catalysis of the reaction: polyprenyl phosphate + UDP-D-glucose = polyprenylphosphate-glucose + UDP.	tmpzr1t_l9r_go_relaxed.owl	uridine diphosphoglucose-polyprenol monophosphate glucosyltransferase activity|UDPglucose:phosphopolyprenol D-glucosyltransferase activity|UDPglucose:polyprenol monophosphate glucosyltransferase activity|UDP-glucose:phosphopolyprenol D-glucosyltransferase activity				MetaCyc:2.4.1.78-RXN|EC:2.4.1.78									molecular_function											owl:Class	
GO:0008813	biolink:NamedThing	chorismate lyase activity	Catalysis of the reaction: chorismate = 4-hydroxybenzoate + pyruvate.	tmpzr1t_l9r_go_relaxed.owl	4-hydroxybenzoate synthetase activity|CPL|chorismate pyruvate-lyase (4-hydroxybenzoate-forming) activity|chorismate pyruvate lyase activity|UbiC|CL				MetaCyc:CHORPYRLY-RXN|EC:4.1.3.40|RHEA:16505|KEGG_REACTION:R01302									molecular_function											owl:Class	
GO:0044310	biolink:NamedThing	osmiophilic body	A membrane-bounded vesicle found predominantly in Plasmodium female gametocytes, that becomes progressively more abundant as the gametocyte reaches full maturity. These vesicles lie beneath the subpellicular membrane of the gametocyte, and the release of their contents into the parasitophorous vacuole has been postulated to aid in the escape of gametocytes from the erythrocyte after ingestion by the mosquito.	tmpzr1t_l9r_go_relaxed.owl								jl	2010-02-18T03:18:32Z					cellular_component											owl:Class	
GO:0090557	biolink:NamedThing	establishment of endothelial intestinal barrier	The establishment of a barrier between endothelial cell layers of the intestine to exert specific and selective control over the passage of water and solutes, thus allowing formation and maintenance of compartments that differ in fluid and solute composition.	tmpzr1t_l9r_go_relaxed.owl								tb	2013-10-29T15:08:27Z					biological_process											owl:Class	
GO:0033769	biolink:NamedThing	glyceollin synthase activity	Catalysis of the reactions: 2-dimethylallyl-(6aS,11aS)-3,6a,9-trihydroxypterocarpan + NADPH + H+ + O2 = glyceollin + NADP+ + 2 H2O, and 4-dimethylallyl-(6aS,11aS)-3,6a,9-trihydroxypterocarpan + NADPH + H+ + O2 = glyceollin + NADP+ + 2 H2O.	tmpzr1t_l9r_go_relaxed.owl	2-(or 4-)dimethylallyl-(6aS,11aS)-3,6a,9-trihydroxypterocarpan,NADPH:oxygen oxidoreductase (cyclizing) activity|dimethylallyl-3,6a,9-trihydroxypterocarpan cyclase activity				EC:1.14.13.85|MetaCyc:2.5.1.36-RXN									molecular_function											owl:Class	
GO:0033712	biolink:NamedThing	1,5-anhydro-D-fructose reductase (1,5-anhydro-D-mannitol-forming) activity	Catalysis of the reaction: 1,5-anhydro-D-mannitol + NADP(+) = 1,5-anhydro-D-fructose + H(+) + NADPH.	tmpzr1t_l9r_go_relaxed.owl	AFR|1,5-anhydro-D-mannitol:NADP+ oxidoreductase activity				MetaCyc:1.1.1.292-RXN|RHEA:24208|EC:1.1.1.292|KEGG_REACTION:R08194									molecular_function											owl:Class	
GO:0051449	biolink:NamedThing	thyrotropin-releasing hormone binding	Binding to thyrotropin-releasing hormone, a tripeptide hormone that stimulates the release of thyroid-stimulating hormone (TSH) and prolactin by the anterior pituitary and it is produced by the hypothalamus and travels across the median eminence to the pituitary via the pituitary portal system.	tmpzr1t_l9r_go_relaxed.owl	thyrotropin releasing hormone binding													molecular_function											owl:Class	
GO:0052638	biolink:NamedThing	indole-3-butyrate beta-glucosyltransferase activity	Catalysis of the reaction: indole-3-butyrate + UDP-D-glucose = indole-3-butyryl-beta-1-D-glucose + UDP.	tmpzr1t_l9r_go_relaxed.owl	UDPglucose:indole-3-butyrate beta-D-glucosyltransferase activity|UDP-glucose:indol-3-ylbutyrate glucosyl-transferase activity|indole-3-butyric acid glucosyltransferase activity|indol-3-ylbutyrylglucose synthase activity|UDPG-indol-3-ylbutyryl glucosyl transferase activity|IBAGlu synthase activity|UDP-glucose:(indol-3-yl)butyrate beta-D-glucosyltransferase activity|IBA-glucose synthase activity|uridine diphosphoglucose-indolebutyrate glucosyltransferase activity|UDP-glucose:indol-3-ylbutyrate glucosyltransferase activity|IBA-Glc synthetase activity				RHEA:62708|MetaCyc:RXN-11655									molecular_function											owl:Class	
GO:0018397	biolink:NamedThing	peptidyl-phenylalanine bromination to L-2'-bromophenylalanine	The bromination of peptidyl-phenylalanine to form L-2'-bromophenylalanine.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0174									biological_process											owl:Class	
GO:0010066	biolink:NamedThing	ground meristem histogenesis	The formation of the primary meristem or meristematic tissue that gives rise to the ground tissues.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0052642	biolink:NamedThing	lysophosphatidic acid phosphatase activity	Catalysis of the reaction: lysophosphatidic acid + H2O = phosphate + monoacylglycerol.	tmpzr1t_l9r_go_relaxed.owl	lysophosphatidate phosphatase activity|LPA phosphatase activity				Reactome:R-HSA-8878654									molecular_function											owl:Class	
GO:0018764	biolink:NamedThing	N-isopropylammelide isopropylaminohydrolase activity	Catalysis of the reaction: N-isopropylammelide + H2O = cyanuric acid + isopropylamine.	tmpzr1t_l9r_go_relaxed.owl	AtzC				MetaCyc:R123-RXN|RHEA:23608|UM-BBD_enzymeID:e0086|EC:3.5.4.42									molecular_function											owl:Class	
GO:0050554	biolink:NamedThing	abietadiene synthase activity	Catalysis of the reaction: (+)-copalyl diphosphate = (-)-abietadiene + diphosphate.	tmpzr1t_l9r_go_relaxed.owl	abietadiene cyclase activity|copalyl-diphosphate diphosphate-lyase (cyclizing)|(+)-copalyl-diphosphate diphosphate-lyase (cyclizing, (-)-abietadiene-forming)				EC:4.2.3.18|KEGG_REACTION:R06301|MetaCyc:4.2.3.18-RXN|RHEA:13873									molecular_function											owl:Class	
GO:0102354	biolink:NamedThing	11-cis-retinol dehydrogenase activity	Catalysis of the reaction: 11-cis-retinol + NADP = 11-cis-retinal + NADPH + H+.	tmpzr1t_l9r_go_relaxed.owl					RHEA:54912|MetaCyc:RXN-13363									molecular_function											owl:Class	
GO:0010190	biolink:NamedThing	cytochrome b6f complex assembly	Formation of cytochrome b6f complex, a complex that transfers electrons from reduced plastoquinone to oxidized plastocyanin and translocates protons from the stroma to the lumen, by the aggregation, arrangement and bonding together of its constituents.	tmpzr1t_l9r_go_relaxed.owl	cytochrome b6f complex biogenesis													biological_process											owl:Class	
GO:0035302	biolink:NamedThing	ecdysteroid 25-hydroxylase activity	Catalysis of the hydroxylation of an ecdysteroid at carbon position 25. Ecdysteroids are a group of polyhydroxylated ketosteroids which initiate post-embryonic development, particularly metamorphosis, in insects and other arthropods.	tmpzr1t_l9r_go_relaxed.owl						Note that in the ecdysteroidogenic pathway, this activity catalyzes the conversion of 2,22,25-trideoxyecdysone (3-beta,5-beta-ketodiol) to 2,22-dideoxyecdysone (3-beta,5-beta-ketotriol).								molecular_function											owl:Class	
GO:0034973	biolink:NamedThing	Sid2-Mob1 complex	A protein complex that contains a protein kinase (Sid2 in S. pombe) and its regulatory subunit (Mob1). The Sid2p-Mob1p kinase complex is a component of the septation initiation network in fission yeast (called the mitotic exit network in S. cerevisiae) and is required for cytokinesis. The analogous complex in S. cerevisiae is called Dbf2p-Mob1p complex.	tmpzr1t_l9r_go_relaxed.owl	Sid2p-Mob1p complex|Sid2-Mob1 kinase complex|Dbf2p-Mob1p complex													cellular_component											owl:Class	
GO:0097719	biolink:NamedThing	neural tissue regeneration	The regrowth of neural tissue following its loss or destruction.	tmpzr1t_l9r_go_relaxed.owl	neuroregeneration							pr	2016-08-25T13:14:27Z					biological_process											owl:Class	
GO:0018590	biolink:NamedThing	methylsilanetriol hydroxylase activity	Catalysis of the reaction: methylsilanetriol + O2 + 2 H+ + 2 e- = H2O + hydroxymethylsilanetriol.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0640									molecular_function											owl:Class	
GO:0004991	biolink:NamedThing	parathyroid hormone receptor activity	Combining with parathyroid hormone to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0052678	biolink:NamedThing	levopimaradiene synthase activity	Catalysis of the reaction: (+)-copalyl diphosphate = abieta-8(14),12-diene + diphosphate.	tmpzr1t_l9r_go_relaxed.owl	ent-copalyl-diphosphate diphosphate-lyase [ent-abieta-8(14),12-diene-forming] activity				MetaCyc:4.2.3.32-RXN|EC:4.2.3.32|RHEA:25548|KEGG_REACTION:R06302									molecular_function											owl:Class	
GO:1904593	biolink:NamedThing	prostaglandin binding	Binding to prostaglandin.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-08-21T18:53:31Z					molecular_function											owl:Class	
GO:0031432	biolink:NamedThing	titin binding	Binding to titin, any of a family of giant proteins found in striated and smooth muscle. In striated muscle, single titin molecules span half the sarcomere, with their N- and C-termini in the Z-disc and M-line, respectively.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0043756	biolink:NamedThing	adenosylcobinamide hydrolase activity	Catalysis of the reaction: adenosylcobinamide + H(2)O = (R)-1-aminopropan-2-ol + adenosylcobyrate.	tmpzr1t_l9r_go_relaxed.owl	adenosylcobinamide amidohydrolase activity|AdoCbi hydrolase activity|CbiZ|AdoCbi amidohydrolase activity				EC:3.5.1.90|RHEA:23504|KEGG_REACTION:R05226|MetaCyc:R346-RXN									molecular_function											owl:Class	
GO:0070984	biolink:NamedThing	SET domain binding	Binding to a SET domain of a protein. SET domains are named after three Drosophila proteins that contain this domain: Su(var), E(z) and trithorax. SET domains are associated with histone lysine methylation.	tmpzr1t_l9r_go_relaxed.owl	SET binding							mah	2009-10-27T04:09:28Z					molecular_function											owl:Class	
GO:0039698	biolink:NamedThing	polyadenylation of viral mRNA by polymerase stuttering	Polyadenylation of viral mRNA through a polymerase stuttering mechanism. The stop signal present at the end of each gene comprises a stretch of uridine on which the viral polymerase acquires a stuttering behavior: after each adenine inserted, the polymerase moves back one nucleotide along with the mRNA. It resumes transcription adding a new adenine, then again moves back, thereby producing a polyA tail.	tmpzr1t_l9r_go_relaxed.owl	polyA stuttering				VZ:1916			bf	2013-10-28T14:54:07Z					biological_process											owl:Class	
GO:0031471	biolink:NamedThing	ethanolamine degradation polyhedral organelle	An organelle found in bacteria consisting of a proteinaceous coat containing enzymes for the degradation of ethanolamine whose purpose is the protection of the rest of the cell from the toxic acetaldehyde product of the enzyme ethanolamine ammonia lyase.	tmpzr1t_l9r_go_relaxed.owl	ethanolamine metabolosome													cellular_component											owl:Class	
GO:0009675	biolink:NamedThing	high-affinity sulfate:proton symporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sulfate(out) + H+(out) = sulfate(in) + H+(in). In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.	tmpzr1t_l9r_go_relaxed.owl	high affinity sulfate:hydrogen symporter activity|high affinity sulphate:hydrogen symporter activity|high affinity sulfate:proton symporter activity													molecular_function											owl:Class	
GO:0005611	biolink:NamedThing	laminin-6 complex	A laminin complex composed of alpha3, beta1 and gamma1 polypeptide chains.	tmpzr1t_l9r_go_relaxed.owl	laminin-6A complex|laminin-311 complex													cellular_component											owl:Class	
GO:0102819	biolink:NamedThing	bixin aldehyde dehydrogenase activity	Catalysis of the reaction: bixin aldehyde + O2 + NAD <=> norbixin + NADH + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-8237									molecular_function											owl:Class	
GO:0009379	biolink:NamedThing	Holliday junction helicase complex	A DNA helicase complex found at Holliday junctions where the helicase activity is involved in the migration of the junction branch point. The best-characterized example is the E. coli RuvAB complex, in which a hexamer of RuvB subunits possesses helicase activity that is modulated by association with RuvA.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0000971	biolink:NamedThing	tRNA exon ligation utilizing 2',3' cyclic phosphate of 5'-exon as source of linkage phosphate	A tRNA exon ligation process in which the splice junction phosphate is derived from the 2',3' cyclic phosphate at the 3'-end of the 5'-exon. This type of ligation to rejoin the 5' and 3' exons of a tRNA is observed in wheat, Chlamydomonas, and vertebrate species including humans.	tmpzr1t_l9r_go_relaxed.owl								krc	2009-04-28T10:36:17Z					biological_process											owl:Class	
GO:0018421	biolink:NamedThing	UDP-N-acetylglucosamine:serine-protein N-acetylglucosamine-1-phosphotransferase activity	Catalysis of the transfer of N-acetylglucosamine-1-phosphate to a serine residue in a protein.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0047246	biolink:NamedThing	luteolin-7-O-glucuronide 7-O-glucuronosyltransferase activity	Catalysis of the reaction: luteolin 7-O-beta-D-glucosiduronate + UDP-alpha-D-glucuronate = H(+) + luteolin 7-O-[(beta-D-glucosiduronate)-(1->2)-(beta-D-glucosiduronate)] + UDP.	tmpzr1t_l9r_go_relaxed.owl	UDP-glucuronate:luteolin 7-O-glucuronide-glucuronosyltransferase activity|UDP-glucuronate:luteolin-7-O-beta-D-glucuronide 2''-O-glucuronosyltransferase activity|luteolin-7-O-glucuronide 2''-O-glucuronosyltransferase activity|LMT activity|uridine diphosphoglucuronate-luteolin 7-O-glucuronide glucuronosyltransferase activity				RHEA:14149|EC:2.4.1.190|KEGG_REACTION:R06827|MetaCyc:2.4.1.190-RXN									molecular_function											owl:Class	
GO:0008959	biolink:NamedThing	phosphate acetyltransferase activity	Catalysis of the reaction: acetyl-CoA + phosphate = CoA + acetyl phosphate.	tmpzr1t_l9r_go_relaxed.owl	phosphoacylase activity|acetyl-CoA:phosphate acetyltransferase activity|PTA|phosphotransacetylase activity				RHEA:19521|EC:2.3.1.8|MetaCyc:PHOSACETYLTRANS-RXN									molecular_function											owl:Class	
GO:0033833	biolink:NamedThing	hydroxymethylfurfural reductase (NADH) activity	Catalysis of the reaction: 5-hydroxymethylfurfural + NADH + H+ = 2,5-bis-hydroxymethylfuran + NAD+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-10738									molecular_function											owl:Class	
GO:0019420	biolink:NamedThing	dissimilatory sulfate reduction	The reduction of sulfate to hydrogen sulfide, which acts as a terminal electron acceptor. Sulfate is activated to adenosine-phosphosulfate (APS) which is then reduced to sulfite, which is in turn reduced to hydrogen sulfide.	tmpzr1t_l9r_go_relaxed.owl	dissimilatory sulphate reduction				MetaCyc:DISSULFRED-PWY									biological_process											owl:Class	
GO:0034673	biolink:NamedThing	inhibin-betaglycan-ActRII complex	A protein complex that consists of inhibin, type III transforming growth factor beta receptor (also known as betaglycan), and the type II activin receptor ActRII. The complex is thought to negatively regulate the activity of activin B.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0042973	biolink:NamedThing	glucan endo-1,3-beta-D-glucosidase activity	Catalysis of the hydrolysis of (1->3)-beta-D-glucosidic linkages in (1->3)-beta-D-glucans.	tmpzr1t_l9r_go_relaxed.owl	endo-(1,3)-beta-D-glucanase activity|oligo-1,3-glucosidase activity|1,3-beta-D-glucan glucanohydrolase activity|endo-1,3-beta-D-glucanase|laminaranase activity|(1->3)-beta-glucan 3-glucanohydrolase activity|1,3-beta-D-glucan 3-glucanohydrolase activity|beta-1,3-glucanase|endo-(1->3)-beta-D-glucanase activity|callase activity|endo-1,3-beta-glucanase activity|kitalase activity|laminarinase activity|endo-1,3-beta-glucosidase activity|(1->3)-beta-glucan endohydrolase activity				EC:3.2.1.39|MetaCyc:3.2.1.39-RXN									molecular_function											owl:Class	
GO:0001326	biolink:NamedThing	replication of extrachromosomal circular DNA	Replication of circular DNA following excision from the chromosome; replication of extrachromosomal circular DNA generally occurs independently of chromosomal replication.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0061581	biolink:NamedThing	corneal epithelial cell migration	The orderly movement of a corneal  epithelial cell from one site to another, often during the development of a multicellular organism.	tmpzr1t_l9r_go_relaxed.owl								dph	2013-12-23T07:28:29Z					biological_process											owl:Class	
GO:0034801	biolink:NamedThing	2,4-dinitrocyclohexanone hydrolase activity	Catalysis of the reaction: 2,4-dinitrocyclohexanone + OH- = 4,6-dinitrohexanoate.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r1069									molecular_function											owl:Class	
GO:0018449	biolink:NamedThing	1-phenylethanol dehydrogenase activity	Catalysis of the reaction: (S)-1-phenylethanol = acetophenone + H2.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0032									molecular_function											owl:Class	
GO:0031696	biolink:NamedThing	alpha-2C adrenergic receptor binding	Binding to an alpha-2C adrenergic receptor.	tmpzr1t_l9r_go_relaxed.owl	alpha-2C adrenergic receptor ligand													molecular_function											owl:Class	
GO:0003942	biolink:NamedThing	N-acetyl-gamma-glutamyl-phosphate reductase activity	Catalysis of the reaction: N-acetyl-L-glutamate 5-semialdehyde + NADP+ + phosphate = N-acetyl-5-glutamyl phosphate + NADPH + H+.	tmpzr1t_l9r_go_relaxed.owl	N-acetylglutamic gamma-semialdehyde dehydrogenase activity|N-acetyl-glutamate semialdehyde dehydrogenase activity|NAGSA dehydrogenase activity|N-acetyl-L-glutamate-5-semialdehyde:NADP+ 5-oxidoreductase (phosphorylating)|N-acetylglutamate 5-semialdehyde dehydrogenase activity|reductase, acetyl-gamma-glutamyl phosphate|N-acetyl-L-glutamate gamma-semialdehyde:NADP oxidoreductase (phosphorylating)				MetaCyc:N-ACETYLGLUTPREDUCT-RXN|EC:1.2.1.38|RHEA:21588									molecular_function											owl:Class	
GO:0080056	biolink:NamedThing	petal vascular tissue pattern formation	Vascular tissue pattern formation as it occurs in the petal of vascular plants.	tmpzr1t_l9r_go_relaxed.owl								dhl	2009-04-13T02:25:01Z					biological_process											owl:Class	
GO:0036199	biolink:NamedThing	cholest-4-en-3-one 26-monooxygenase activity	Catalysis of the reaction: cholest-4-en-3-one + NADH + H+ + O2 = 26-hydroxycholest-4-en-3-one + NAD+ + H2O. This reaction involves the hydroxylation of the C26 carbon, followed by oxidation of the alcohol to the carboxylic acid via the aldehyde intermediate.	tmpzr1t_l9r_go_relaxed.owl					RHEA:51564|KEGG_REACTION:R09859|EC:1.14.15.29			bf	2012-04-20T02:03:05Z					molecular_function											owl:Class	
GO:0098536	biolink:NamedThing	deuterosome	A spherical, electron dense, cytoplasmic structure that is involved in de novo assembly of centrioles.	tmpzr1t_l9r_go_relaxed.owl								dos	2013-10-22T16:21:19Z					cellular_component											owl:Class	
GO:0031800	biolink:NamedThing	type 3 metabotropic glutamate receptor binding	Binding to a type 3 metabotropic glutamate receptor.	tmpzr1t_l9r_go_relaxed.owl	type 3 metabotropic glutamate receptor ligand													molecular_function											owl:Class	
GO:0000907	biolink:NamedThing	sulfonate dioxygenase activity	Catalysis of the reaction: sulfonate + 2-oxoglutarate + O2 = sulfite + aminoacetaldehyde + succinate + CO2.	tmpzr1t_l9r_go_relaxed.owl	sulfonate/alpha-ketoglutarate dioxygenase activity|sulphonate dioxygenase activity													molecular_function											owl:Class	
GO:0047067	biolink:NamedThing	hydrogen:quinone oxidoreductase activity	Catalysis of the reaction: H(2) + menaquinone = reduced menaquinone.	tmpzr1t_l9r_go_relaxed.owl	hydrogen:menaquinone oxidoreductase activity|quinone-reactive Ni/Fe-hydrogenase activity|hydrogen-ubiquinone oxidoreductase activity|membrane-bound hydrogenase activity				RHEA:18641|MetaCyc:1.12.5.1-RXN|EC:1.12.5.1|KEGG_REACTION:R02965									molecular_function											owl:Class	
GO:0047837	biolink:NamedThing	D-xylose 1-dehydrogenase (NADP+) activity	Catalysis of the reaction: D-xylose + NADP(+) = D-xylono-1,5-lactone + H(+) + NADPH.	tmpzr1t_l9r_go_relaxed.owl	D-xylose-NADP dehydrogenase activity|D-xylose (nicotinamide adenine dinucleotide phosphate) dehydrogenase activity|D-xylose:NADP+ 1-oxidoreductase activity|D-xylose:NADP+ oxidoreductase activity				MetaCyc:D-XYLOSE-1-DEHYDROGENASE-NADP+-RXN|EC:1.1.1.179|RHEA:22000|KEGG_REACTION:R01430									molecular_function											owl:Class	
GO:1904852	biolink:NamedThing	trimethylamine-N-oxide reductase (cytochrome c) complex	A protein complex which is capable of trimethylamine-N-oxide reductase (cytochrome c) activity.	tmpzr1t_l9r_go_relaxed.owl						An example of this is TorA in E. coli (UniProt ID P33225) in PMID:11056172 (inferred from direct assay).		bhm	2015-12-14T09:11:10Z					cellular_component											owl:Class	
GO:0106076	biolink:NamedThing	peptide-lysine-N-succinyltransferase activity	Catalysis of the reaction: succinyl-CoA + lysine in peptide = CoA + N-succinyl-lysine-peptide.	tmpzr1t_l9r_go_relaxed.owl								hjd	2017-12-15T18:25:16Z					molecular_function											owl:Class	
GO:0050215	biolink:NamedThing	propanediol dehydratase activity	Catalysis of the reaction: propane-1,2-diol = H(2)O + propanal.	tmpzr1t_l9r_go_relaxed.owl	1,2-propanediol dehydratase activity|coenzyme B12-dependent diol dehydrase activity|meso-2,3-butanediol dehydrase activity|propane-1,2-diol hydro-lyase activity|DL-1,2-propanediol hydro-lyase activity|propanediol dehydrase activity|propane-1,2-diol hydro-lyase (propanal-forming)|dioldehydratase activity|diol dehydratase activity|adenosylcobalamin-dependent diol dehydratase activity|diol dehydrase activity				MetaCyc:PROPANEDIOL-DEHYDRATASE-RXN|EC:4.2.1.28|KEGG_REACTION:R02376|RHEA:14569									molecular_function											owl:Class	
GO:0018447	biolink:NamedThing	chloral hydrate dehydrogenase activity	Catalysis of the reactions: chloral hydrate = 3 H+ + 2 e- + trichloroacetate, and chloral hydrate + H2 = H2O + trichloroethanol.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_enzymeID:e0229									molecular_function											owl:Class	
GO:0031769	biolink:NamedThing	glucagon receptor binding	Binding to a glucagon receptor.	tmpzr1t_l9r_go_relaxed.owl	glucagon receptor ligand													molecular_function											owl:Class	
GO:0102007	biolink:NamedThing	acyl-L-homoserine-lactone lactonohydrolase activity	Catalysis of the reaction: H2O + an N-acyl-L-homoserine lactone <=> H+ + an N-acyl-L-homoserine.	tmpzr1t_l9r_go_relaxed.owl					EC:3.1.1.81|Reactome:R-HSA-8932633|MetaCyc:3.1.1.81-RXN|RHEA:22576									molecular_function											owl:Class	
GO:0004832	biolink:NamedThing	valine-tRNA ligase activity	Catalysis of the reaction: L-valine + ATP + tRNA(Val) = L-valyl-tRNA(Val) + AMP + diphosphate + 2 H(+).	tmpzr1t_l9r_go_relaxed.owl	valine translase activity|valyl-transfer ribonucleate synthetase activity|valyl-transfer ribonucleic acid synthetase activity|L-valine:tRNAVal ligase (AMP-forming)|valyl-transfer RNA synthetase activity|valyl-tRNA synthetase activity|valine transfer ribonucleate ligase activity				EC:6.1.1.9|Reactome:R-HSA-380042|MetaCyc:VALINE--TRNA-LIGASE-RXN|RHEA:10704|KEGG_REACTION:R03665|Reactome:R-HSA-380199									molecular_function											owl:Class	
GO:0039623	biolink:NamedThing	T=25 icosahedral viral capsid	The protein coat that surrounds the infective nucleic acid in some virus particles where the subunits (capsomeres) are arranged to form an icosahedron with T=25 symmetry. The T=25 capsid is composed of 12 pentameric and 240 hexameric capsomeres.	tmpzr1t_l9r_go_relaxed.owl					VZ:810			bf	2012-07-18T02:21:43Z					cellular_component											owl:Class	
GO:0098873	biolink:NamedThing	neuronal action potential back-propagation	Propagation of an action potential in a neuron, from its site of initiation (typically the axon hillock) towards the soma.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0005144	biolink:NamedThing	interleukin-13 receptor binding	Binding to an interleukin-13 receptor.	tmpzr1t_l9r_go_relaxed.owl	interleukin-13 receptor ligand|IL-13													molecular_function											owl:Class	
GO:0009044	biolink:NamedThing	xylan 1,4-beta-xylosidase activity	Catalysis of the hydrolysis of (1->4)-beta-D-xylans so as to remove successive D-xylose residues from the non-reducing termini.	tmpzr1t_l9r_go_relaxed.owl	beta-D-xylopyranosidase activity|exo-1,4-xylosidase activity|xylobiase activity|exo-1,4-beta-D-xylosidase activity|1,4-beta-D-xylan xylohydrolase activity|exo-1,4-beta-xylosidase activity|beta-xylosidase activity				MetaCyc:3.2.1.37-RXN|EC:3.2.1.37									molecular_function											owl:Class	
GO:0018829	biolink:NamedThing	1,1-dichloro-2,2-bis(4-chlorophenyl)ethane dehydrochlorinase activity	Catalysis of the reaction: 1,1-dichloro-2,2-bis(4-chlorophenyl)ethane = HCl + 1-chloro-2,2-bis(4-chlorophenyl)ethene. 1,1-dichloro-2,2-bis(4-chlorophenyl)ethane is also known as DDD; 1-chloro-2,2-bis(4-chlorophenyl)ethene is also known as DDMU.	tmpzr1t_l9r_go_relaxed.owl	DDD dehydrochlorinase activity				EC:4.5.1.-|UM-BBD_reactionID:r0513									molecular_function											owl:Class	
GO:0097663	biolink:NamedThing	SCF-Dia2/Pof3 ubiquitin ligase complex	An SCF ubiquitin ligase complex in which the F-box protein is Dia2 in S. cerevisiae (Pof3 in S. pombe).	tmpzr1t_l9r_go_relaxed.owl								pr	2014-10-06T10:26:44Z					cellular_component											owl:Class	
GO:0036358	biolink:NamedThing	lipoteichoic acid D-alanylation	The formation of a D-alanyl ester of lipoteichoic acid by transfer of D-Ala onto a membrane-associated lipoteichoic acid (LTA).	tmpzr1t_l9r_go_relaxed.owl	D-alanyl lipoteichoic acid formation|LTA D-alanylation|D-alanyl LTA formation							bf	2012-09-19T15:09:05Z					biological_process											owl:Class	
GO:0102166	biolink:NamedThing	[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine O-N-acetyl-alpha-D-glucosaminase activity	Catalysis of the reaction: H2O + an N-acetyl-alpha-D-glucosaminyl-L-threonine-[glycoprotein] <=> N-acetyl-alpha-D-glucosaminide + a [protein]-L-threonine.	tmpzr1t_l9r_go_relaxed.owl					EC:3.2.1.169|RHEA:48892|MetaCyc:RXN-11891									molecular_function											owl:Class	
GO:0035552	biolink:NamedThing	oxidative single-stranded DNA demethylation	Removal of the methyl group from one or more nucleotides within a single-stranded DNA molecule involving the oxidation (i.e. electron loss) of one or more atoms.	tmpzr1t_l9r_go_relaxed.owl	oxidative ssDNA demethylation							bf	2010-05-14T11:03:55Z					biological_process											owl:Class	
GO:0033453	biolink:NamedThing	GCU codon-amino acid adaptor activity	A triplet codon-amino acid adaptor activity that recognizes a GCU codon.	tmpzr1t_l9r_go_relaxed.owl	GCT codon-amino acid adaptor activity|alanine tRNA					Note that in the standard genetic code, GCT codes for alanine.								molecular_function											owl:Class	
GO:0004749	biolink:NamedThing	ribose phosphate diphosphokinase activity	Catalysis of the reaction: D-ribose 5-phosphate + ATP = 5-phospho-alpha-D-ribose 1-diphosphate + AMP + 2 H(+).	tmpzr1t_l9r_go_relaxed.owl	PRPP synthetase activity|phosphoribosyl-diphosphate synthetase activity|ribose-phosphate pyrophosphokinase activity|5-phosphoribosyl-1-pyrophosphate synthetase activity|ATP:D-ribose-5-phosphate diphosphotransferase activity|phosphoribosyl pyrophosphate synthetase activity|5-phosphoribose pyrophosphorylase activity|PP-ribose P synthetase activity|phosphoribosylpyrophosphate synthase activity|PPRibP synthetase activity|5-phosphoribosyl-alpha-1-pyrophosphate synthetase activity|phosphoribosyl diphosphate synthetase activity|pyrophosphoribosylphosphate synthetase activity|ribose-5-phosphate pyrophosphokinase activity|ribose-phosphate diphosphokinase activity|phosphoribosylpyrophosphate synthetase activity|ribophosphate pyrophosphokinase activity				MetaCyc:PWY0-662|MetaCyc:PRPPSYN-RXN|Reactome:R-HSA-73580|RHEA:15609|Reactome:R-HSA-111215|EC:2.7.6.1|KEGG_REACTION:R01049									molecular_function											owl:Class	
GO:0097304	biolink:NamedThing	lipoprotein biosynthetic process via signal peptide cleavage	The chemical reactions and pathways by which signal peptide cleavage leads to formation of a water-soluble protein-lipid complex.	tmpzr1t_l9r_go_relaxed.owl	lipoprotein biosynthesis (signal peptide cleavage)							pr	2012-05-15T01:05:17Z					biological_process											owl:Class	
GO:0047474	biolink:NamedThing	long-chain fatty acid luciferin component ligase activity	Catalysis of the reaction: protein + an acid + ATP = an acyl-protein thiolester + diphosphate + AMP. A long-chain fatty acid is a fatty acid with a chain length between C13 and C22.	tmpzr1t_l9r_go_relaxed.owl	long-chain-fatty-acid:protein ligase (AMP-forming)|long-chain-fatty-acid-luciferin-component ligase activity|long-chain-fatty-acid luciferin component ligase activity|acyl-protein synthetase activity				MetaCyc:6.2.1.19-RXN|RHEA:20101|EC:6.2.1.19									molecular_function											owl:Class	
GO:0120268	biolink:NamedThing	paraflagellar rod assembly	The aggregation, arrangement and bonding together of a set of components to form a paraflagellar rod, a large lattice-like axial structure found in some flagellated protists which extends alongside the axoneme.	tmpzr1t_l9r_go_relaxed.owl	paraflagellar rod formation|PFR assembly|paraflagellar rod biogenesis	https://github.com/geneontology/go-ontology/issues/20053						krc	2020-09-30T17:46:14Z					biological_process											owl:Class	
GO:0061504	biolink:NamedThing	cyclic threonylcarbamoyladenosine biosynthetic process	The chemical reactions and pathways resulting in the formation of cyclic threonylcarbamoyladenosine, a modified nucleoside found in some tRNA molecules.	tmpzr1t_l9r_go_relaxed.owl								dph	2013-01-22T14:25:00Z					biological_process											owl:Class	
GO:0047299	biolink:NamedThing	tryptophan-phenylpyruvate transaminase activity	Catalysis of the reaction: keto-phenylpyruvate + L-tryptophan = 3-(indol-3-yl)pyruvate + L-phenylalanine.	tmpzr1t_l9r_go_relaxed.owl	L-tryptophan-alpha-ketoisocaproate aminotransferase activity|tryptophan-phenylpyruvate aminotransferase activity|tryptophan--phenylpyruvate aminotransferase activity|L-tryptophan:phenylpyruvate aminotransferase activity				RHEA:13741|EC:2.6.1.28|MetaCyc:2.6.1.28-RXN|KEGG_REACTION:R01376									molecular_function											owl:Class	
GO:0018568	biolink:NamedThing	3,4-dihydroxyphenanthrene dioxygenase activity	Catalysis of the reaction: 3,4-dihydroxyphenanthrene + O2 = H+ + 2-hydroxy-2 H-benzo[h]chromene-2-carboxylate.	tmpzr1t_l9r_go_relaxed.owl					EC:1.13.11.-|UM-BBD_reactionID:r0501									molecular_function											owl:Class	
GO:0071339	biolink:NamedThing	MLL1 complex	A protein complex that can methylate lysine-4 of histone H3. MLL1/MLL is the catalytic methyltransferase subunit, and the complex also contains the core components ASH2L, HCFC1/HCF1 WDR5 and RBBP5.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-12-11T11:11:36Z					cellular_component											owl:Class	
GO:0102161	biolink:NamedThing	copal-8-ol diphosphate synthase activity	Catalysis of the reaction: copal-8-ol diphosphate <=> 2-trans,6-trans,10-trans-geranylgeranyl diphosphate + H2O.	tmpzr1t_l9r_go_relaxed.owl					EC:4.2.1.133|RHEA:32703|MetaCyc:RXN-11772									molecular_function											owl:Class	
GO:0070698	biolink:NamedThing	type I activin receptor binding	Binding to a type I activin receptor.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-06-04T04:15:21Z					molecular_function											owl:Class	
GO:0060321	biolink:NamedThing	acceptance of pollen	The process, involving the sharing and interaction of the single locus incompatibility haplotypes, involved in the acceptance of pollen by cells in the stigma.	tmpzr1t_l9r_go_relaxed.owl	acceptance of non-self pollen|acceptance of self pollen													biological_process											owl:Class	
GO:0047454	biolink:NamedThing	phaseollidin hydratase activity	Catalysis of the reaction: phaseollidin hydrate = H(2)O + phaseollidin.	tmpzr1t_l9r_go_relaxed.owl	phaseollidin-hydrate hydro-lyase (phaseollidin-forming)|phaseollidin-hydrate hydro-lyase activity				MetaCyc:4.2.1.97-RXN|EC:4.2.1.97|RHEA:19769|KEGG_REACTION:R04728									molecular_function											owl:Class	
GO:0044245	biolink:NamedThing	polysaccharide digestion	The whole of the physical, chemical, and biochemical processes carried out by living organisms to break down ingested polysaccharides into components that may be easily absorbed and directed into metabolism.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0034730	biolink:NamedThing	SmD-containing SMN-Sm protein complex	An SMN-Sm protein complex formed by the association of the methylated Sm proteins B/B', D1, D2, D3, E, F, and G with the SMN complex.	tmpzr1t_l9r_go_relaxed.owl	SMN-containing protein complex													cellular_component											owl:Class	
GO:0106231	biolink:NamedThing	protein-propionyllysine depropionylase activity	Catalysis of the reaction:H2O + N(6)-propanoyl-L-lysyl-[protein] + NAD(+) = 3''-O-propanoyl-ADP-D-ribose + L-lysyl-[protein] + nicotinamide.	tmpzr1t_l9r_go_relaxed.owl					RHEA:23500	This reaction is the removal of a propionyl group from a propionylated lysine residue of a protein or peptide.		hjd	2019-10-18T14:14:47Z					molecular_function											owl:Class	
GO:0050412	biolink:NamedThing	cinnamate beta-D-glucosyltransferase activity	Catalysis of the reaction: trans-cinnamate + UDP-D-glucose = 1-O-trans-cinnamoyl-beta-D-glucopyranose + UDP.	tmpzr1t_l9r_go_relaxed.owl	UDPglucose:trans-cinnamate beta-D-glucosyltransferase activity|UDPG:t-cinnamate glucosyltransferase activity|cinnamate b-D-glucosyltransferase activity|UDP-glucose:trans-cinnamate beta-D-glucosyltransferase activity|cinnamate glucosyltransferase activity|uridine diphosphoglucose-cinnamate glucosyltransferase activity				KEGG_REACTION:R02256|MetaCyc:CINNAMATE-GLUCOSYLTRANSFERASE-RXN|EC:2.4.1.177|RHEA:13437									molecular_function											owl:Class	
GO:0045480	biolink:NamedThing	galactose oxidase activity	Catalysis of the reaction: D-galactose + O2 = D-galacto-hexodialdose + hydrogen peroxide.	tmpzr1t_l9r_go_relaxed.owl	D-galactose oxidase activity|D-galactose:oxygen 6-oxidoreductase activity|beta-galactose oxidase activity				MetaCyc:GALACTOSE-OXIDASE-RXN|RHEA:24160|EC:1.1.3.9									molecular_function											owl:Class	
GO:0102323	biolink:NamedThing	2-isopropylphenol monooxygenase activity	Catalysis of the reaction: 2-isopropylphenol + O2 + NADH + H+ = 3-isopropylcatechol + H2O + NAD.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-13152									molecular_function											owl:Class	
GO:0042497	biolink:NamedThing	triacyl lipopeptide binding	Binding to a lipopeptide containing a nonprotein moiety consisting of three acyl groups.	tmpzr1t_l9r_go_relaxed.owl	bacterial triacyl lipoprotein binding|bacterial triacyl lipopeptide binding|triacylated lipopeptide binding					Note that bacterial lipopeptides are derived from bacterial lipoproteins, but the two terms are sometimes used interchangeably in the literature.								molecular_function											owl:Class	
GO:0047141	biolink:NamedThing	glutathione-cystine transhydrogenase activity	Catalysis of the reaction: cystine + 2 reduced glutathione = oxidized glutathione + 2 L-cysteine.	tmpzr1t_l9r_go_relaxed.owl	glutathione:cystine oxidoreductase|NADPH-dependent GSH-cystine transhydrogenase|GSH-cystine transhydrogenase				EC:1.8.4.4|MetaCyc:1.8.4.4-RXN|RHEA:12613									molecular_function											owl:Class	
GO:0103043	biolink:NamedThing	5-phospho-alpha-D-ribosyl 1,2-cyclic phosphate phosphodiesterase activity	Catalysis of the reaction: 5-phosphonato-alpha-D-ribose cyclic-1,2-phosphate + H2O <=> H+ + alpha-D-ribose 1,5-bisphosphate.	tmpzr1t_l9r_go_relaxed.owl					RHEA:34795|MetaCyc:RXN0-6710|EC:3.1.4.55									molecular_function											owl:Class	
GO:0098061	biolink:NamedThing	viral capsid, internal space	The region of a virus contained within the capsid shell, and usually containing the viral genome and accessory proteins.	tmpzr1t_l9r_go_relaxed.owl	internal head protein							bm	2012-08-01T12:12:47Z					cellular_component											owl:Class	
GO:0047320	biolink:NamedThing	D-4-hydroxyphenylglycine transaminase activity	Catalysis of the reaction: 2-oxoglutarate + D-4-hydroxyphenylglycine = 4-hydroxyphenylglyoxylate + L-glutamate.	tmpzr1t_l9r_go_relaxed.owl	D-4-hydroxyphenylglycine aminotransferase activity|D-hydroxyphenylglycine aminotransferase activity|D-4-hydroxyphenylglycine:2-oxoglutarate aminotransferase activity				EC:2.6.1.72|KEGG_REACTION:R04234|RHEA:15589|MetaCyc:2.6.1.72-RXN									molecular_function											owl:Class	
GO:0103063	biolink:NamedThing	trans-keto-C61-meroacyl-AMP ligase activity	Catalysis of the reaction: ATP(4-) + H2O + a trans-keto-C61-meroacyl-[acp] <=> diphosphoric acid + a trans-keto-meroacyl-adenylate + a holo-[acyl-carrier protein].	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN1G-4143									molecular_function											owl:Class	
GO:0051997	biolink:NamedThing	2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase activity	Catalysis of the reaction: 5-hydroxy-2-oxo-4-ureido-2,5-dihydro-1H imidazole-5-carboxylate + H+ = S-allantoin + CO2.	tmpzr1t_l9r_go_relaxed.owl	4-(carbamoylamino)-5-hydroxy-2-oxo-2,5-dihydro-1H-imidazole-5-carboxylate decarboxylase activity|OHCU decarboxylase activity				RHEA:26301|KEGG_REACTION:R06604|MetaCyc:RXN-6201			ai	2010-07-19T10:47:15Z					molecular_function											owl:Class	
GO:0046362	biolink:NamedThing	ribitol biosynthetic process	The chemical reactions and pathways resulting in the formation of ribitol, a pentitol derived formally by reduction of the -CHO group of either D- or L-ribose.	tmpzr1t_l9r_go_relaxed.owl	ribitol anabolism|ribitol formation|ribitol biosynthesis|ribitol synthesis													biological_process											owl:Class	
GO:0030754	biolink:NamedThing	apigenin 4'-O-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + 5,7,4'-trihydroxyflavone = S-adenosyl-L-homocysteine + 4'-methoxy-5,7-dihydroxyflavone.	tmpzr1t_l9r_go_relaxed.owl	flavonoid O-methyltransferase activity|S-adenosyl-L-methionine:5,7,4'-trihydroxyflavone 4'-O-methyltransferase activity|flavonoid methyltransferase activity				RHEA:20429|MetaCyc:APIGENIN-4-O-METHYLTRANSFERASE-RXN|EC:2.1.1.75									molecular_function											owl:Class	
GO:0047731	biolink:NamedThing	catechol oxidase (dimerizing) activity	Catalysis of the reaction: 4 catechol + 3 O2 = 2 dibenzo[1,4]dioxin-2,3-dione + 6 H2O.	tmpzr1t_l9r_go_relaxed.owl	catechol:oxygen oxidoreductase (dimerizing)				EC:1.1.3.14|MetaCyc:CATECHOL-OXIDASE-DIMERIZING-RXN|RHEA:12809									molecular_function											owl:Class	
GO:0106376	biolink:NamedThing	2-hydroxyphytanoyl-CoA lyase activity	Catalysis of the reaction: 2-hydroxyphytanoyl-CoA = 2,6,10,14-tetramethylpentadecanal + formyl-CoA.	tmpzr1t_l9r_go_relaxed.owl					RHEA:25355			hjd	2021-04-16T12:47:53Z					molecular_function											owl:Class	
GO:0045353	biolink:NamedThing	interleukin-1 type II receptor antagonist activity	Blocks the binding of interleukin-1 to interleukin-1 type II receptors.	tmpzr1t_l9r_go_relaxed.owl	IL-1ra type II													molecular_function											owl:Class	
GO:0052741	biolink:NamedThing	(R)-limonene 6-monooxygenase activity	Catalysis of the reaction: (4R)-limonene + H+ + NADPH + O2 = (1R,5S)-carveol + H2O + NADP+.	tmpzr1t_l9r_go_relaxed.owl	(+)-limonene 6-monooxygenase activity|(+)-limonene-6-hydroxylase activity|(R)-limonene,NADPH:oxygen oxidoreductase (6-hydroxylating) activity				RHEA:18957|KEGG_REACTION:R06119|MetaCyc:1.14.13.84-RXN|EC:1.14.14.53									molecular_function											owl:Class	
GO:0097667	biolink:NamedThing	SCF-Rcy1/Pof6 ubiquitin ligase complex	An SCF ubiquitin ligase complex in which the F-box protein is Rcy1 in S. cerevisiae (Pof6 in S. pombe).	tmpzr1t_l9r_go_relaxed.owl								pr	2014-10-06T10:28:09Z					cellular_component											owl:Class	
GO:0001601	biolink:NamedThing	peptide YY receptor activity	Combining with gut peptide YY to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0047672	biolink:NamedThing	anthranilate N-benzoyltransferase activity	Catalysis of the reaction: anthranilate + benzoyl-CoA = N-benzoylanthranilate + CoA.	tmpzr1t_l9r_go_relaxed.owl	benzoyl-CoA:anthranilate N-benzoyltransferase				KEGG_REACTION:R02453|EC:2.3.1.144|MetaCyc:ANTHRANILATE-N-BENZOYLTRANSFERASE-RXN|RHEA:21600									molecular_function											owl:Class	
GO:0050269	biolink:NamedThing	coniferyl-aldehyde dehydrogenase activity	Catalysis of the reaction: coniferyl aldehyde + H2O + NAD(P)+ = ferulate + NAD(P)H + H+.	tmpzr1t_l9r_go_relaxed.owl	coniferyl aldehyde:NAD(P)+ oxidoreductase activity				EC:1.2.1.68|MetaCyc:RXN-1241									molecular_function											owl:Class	
GO:0102256	biolink:NamedThing	neoagarohexaose 1,3-alpha-3,6-anhydro-L-galactosidase activity	Catalysis of the reaction: neoagarohexaose + H2O <=> 3,6-anhydro-alpha-L-galactopyranose + agaropentaose.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-12429|EC:3.2.1.159									molecular_function											owl:Class	
GO:0043957	biolink:NamedThing	acryloyl-CoA reductase (NADP+) activity	Catalysis of the reaction: acryloyl-CoA + NADPH + H+ = propionyl-CoA + NADP+.	tmpzr1t_l9r_go_relaxed.owl	enoyl-CoA hydratase/isomerase|AMP-dependent synthetase and ligase:enoyl-CoA hydratase/isomerase|acetyl-coenzyme A synthetase/GroES-like domain|acryloyl-CoA reductase (NADPH) activity|acrylyl-CoA reductase (NADPH) activity|acetyl-coenzyme A synthetase|AMP-dependent synthetase and ligase				EC:1.3.1.84|MetaCyc:RXN-9087|RHEA:26454|KEGG_REACTION:R00919	Note that this function is one of the activities of the trifunctional enzyme propionyl-coenzyme A synthase. See PMID:11821399.								molecular_function											owl:Class	
GO:0102879	biolink:NamedThing	(+)-thujopsene synthase activity	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate <=> (+)-thujopsene + diphosphoric acid.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-8418|RHEA:30375|EC:4.2.3.79									molecular_function											owl:Class	
GO:0033987	biolink:NamedThing	2-hydroxyisoflavanone dehydratase activity	Catalysis of the reaction: 2,7,4'-trihydroxyisoflavanone = daidzein + H2O.	tmpzr1t_l9r_go_relaxed.owl	2,7,4'-trihydroxyisoflavanone hydro-lyase (daidzein-forming) activity|2,7,4'-trihydroxyisoflavanone hydro-lyase activity				MetaCyc:RXN-3284|RHEA:16445|EC:4.2.1.105									molecular_function											owl:Class	
GO:0034838	biolink:NamedThing	menthone dehydrogenase activity	Catalysis of the reaction: (-)-(2S,5R)-menthone + NAD+ = (5R)-menth-2-enone + NADH + H+.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r1183									molecular_function											owl:Class	
GO:1901514	biolink:NamedThing	ATPase-coupled lipo-chitin oligosaccharide transmembrane transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + lipo-chitin oligosaccharide(in) = ADP + phosphate + lipo-chitin oligosaccharide(out).	tmpzr1t_l9r_go_relaxed.owl	lipo-chitin oligosaccharide transmembrane-transporting ATPase activity							jl	2012-10-18T11:52:55Z					molecular_function											owl:Class	
GO:0102626	biolink:NamedThing	parthenolide synthase activity	Catalysis of the reaction: costunolide + NADPH + O2 + H+ <=> parthenolide + NADP(3-) + H2O.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-15531									molecular_function											owl:Class	
GO:0019149	biolink:NamedThing	3-chloro-D-alanine dehydrochlorinase activity	Catalysis of the reaction: 3-chloro-D-alanine + H2O = pyruvate + chloride + NH3.	tmpzr1t_l9r_go_relaxed.owl	3-chloro-D-alanine chloride-lyase (deaminating)|beta-chloro-D-alanine dehydrochlorinase activity|3-chloro-D-alanine chloride-lyase (deaminating; pyruvate-forming)				RHEA:18873|MetaCyc:3-CHLORO-D-ALANINE-DEHYDROCHLORINASE-RXN|EC:4.5.1.2									molecular_function											owl:Class	
GO:0061690	biolink:NamedThing	lipoamidase activity	Catalysis of the cleavage of the amide bond to release lipoic acid from a lipoylated protein.	tmpzr1t_l9r_go_relaxed.owl	lipoyl-X-hydrolase				MetaCyc:RXN-13031			dph	2015-05-05T10:06:49Z					molecular_function											owl:Class	
GO:0019479	biolink:NamedThing	L-alanine oxidation to D-lactate and ammonia	The chemical reactions and pathways resulting in the breakdown of L-alanine to D-lactate and ammonia.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:ALACAT2-PWY									biological_process											owl:Class	
GO:0035585	biolink:NamedThing	calcium-mediated signaling using extracellular calcium source	A series of molecular signals in which a cell uses calcium ions imported from an extracellular source to convert a signal into a response.	tmpzr1t_l9r_go_relaxed.owl	extracellular calcium influx|calcium signalling using extracellular calcium source|calcium signaling using extracellular calcium source|calcium-mediated signalling using extracellular calcium source							bf	2010-10-18T11:04:27Z					biological_process											owl:Class	
GO:0019824	biolink:NamedThing	P6 peroxisome	A subform of peroxisome that corresponds to an intermediate in a peroxisome assembly pathway, which operates by conversion of peroxisomal subforms in the direction P1, P2 -> P3 -> P4 -> P5 -> P6. P6 peroxisomes are distinguished from the other subforms on the bases of buoyant density and protein content, and are equivalent to mature peroxisomes.	tmpzr1t_l9r_go_relaxed.owl	peroxisome vesicle					Note that this peroxisome assembly pathway is described in the yeast Yarrowia lipolytica. See also the cellular component terms 'P1 peroxisome ; GO:0019819', 'P2 peroxisome ; GO:0019820', 'P3 peroxisome ; GO:0019821', 'P4 peroxisome ; GO:0019822', and 'P5 peroxisome ; GO:0019823'.								cellular_component											owl:Class	
GO:0080031	biolink:NamedThing	methyl salicylate esterase activity	Catalysis of the reaction: methyl salicylate + H2O = salicylic acid + methanol + H+.	tmpzr1t_l9r_go_relaxed.owl	MESA esterase activity|salicylic acid methyl ester esterase activity|methyl SA esterase activity|methylsalicylate esterase activity				MetaCyc:RXNQT-4366									molecular_function											owl:Class	
GO:0004198	biolink:NamedThing	calcium-dependent cysteine-type endopeptidase activity	Catalysis of the hydrolysis of nonterminal peptide bonds in a polypeptide chain by a mechanism using a cysteine residue at the enzyme active center, and requiring the presence of calcium.	tmpzr1t_l9r_go_relaxed.owl	calpain activity				Reactome:R-HSA-8848658|Reactome:R-HSA-8863012									molecular_function											owl:Class	
GO:0017041	biolink:NamedThing	galactosylgalactosylglucosylceramidase activity	Catalysis of the reaction: D-galactosyl-D-galactosyl-D-glucosyl-N-acylsphingosine + H2O = lactosyl-N-acylsphingosine + D-galactose.	tmpzr1t_l9r_go_relaxed.owl	trihexosylceramide alpha-galactosidase activity|trihexosyl ceramide galactosidase activity|ceramide trihexosidase activity|D-galactosyl-D-galactosyl-D-glucosyl-N-acylsphingosine galactohydrolase activity|ceramidetrihexosidase activity|ceramidetrihexoside alpha-galactosidase activity				EC:3.2.1.47|RHEA:21112|MetaCyc:3.2.1.47-RXN									molecular_function											owl:Class	
GO:1990506	biolink:NamedThing	mitotic DNA-dependent DNA replication	A DNA replication process that uses parental DNA as a template for the DNA-dependent DNA polymerases that synthesize the new strands during the mitotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl								al	2014-10-01T14:13:23Z					biological_process											owl:Class	
GO:0008666	biolink:NamedThing	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase activity	Catalysis of the reaction: (S)-2,3,4,5-tetrahydrodipicolinate + H(2)O + succinyl-CoA = L-2-succinylamino-6-oxopimelate + CoA.	tmpzr1t_l9r_go_relaxed.owl	succinyl-CoA:2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase activity|tetrahydropicolinate succinylase activity|tetrahydrodipicolinate N-succinyltransferase activity|succinyl-CoA:tetrahydrodipicolinate N-succinyltransferase activity|succinyl-CoA:(S)-2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase activity|tetrahydrodipicolinate succinyltransferase activity|THDP N-succinyltransferase activity|tetrahydrodipicolinate succinylase activity				RHEA:17325|KEGG_REACTION:R04365|MetaCyc:TETHYDPICSUCC-RXN|EC:2.3.1.117									molecular_function											owl:Class	
GO:0140240	biolink:NamedThing	perforant pathway to dendrate granule cell synapse	A neuron to neuron synapse of a pyramidal neuron in the entorhinal cortex onto a granule cell in the dentate gyrus of the hippocampus.	tmpzr1t_l9r_go_relaxed.owl	perforant pathway to DG granule cell synapse	https://github.com/geneontology/synapse/issues/234						pg	2018-07-15T08:21:43Z					cellular_component											owl:Class	
GO:0030625	biolink:NamedThing	U11 snRNA binding	Binding to a U11 small nuclear RNA (U11 snRNA).	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0102556	biolink:NamedThing	dammarenediol 12-hydroxylase activity	Catalysis of the reaction: dammarenediol-II + NADPH + H+ + O2 <=> (20S)-protopanaxadiol + NADP + H2O.	tmpzr1t_l9r_go_relaxed.owl					EC:1.14.14.120|MetaCyc:RXN-14975|RHEA:38579									molecular_function											owl:Class	
GO:0080103	biolink:NamedThing	4-methylthiopropyl glucosinolate S-oxygenase activity	Catalysis of the reaction: 4-methylthiopropyl-glucosinolate = 4-methylsulfinylpropyl-glucosinolate.	tmpzr1t_l9r_go_relaxed.owl								dhl	2009-04-23T04:27:45Z					molecular_function											owl:Class	
GO:0043777	biolink:NamedThing	cobalt-precorrin-7 C15-methyltransferase activity	Catalysis of the reaction: cobalt-precorrin 7 + S-adenosyl-L-methionine = cobalt-precorrin 8 + S-adenosyl-L-homocysteine + CO2.	tmpzr1t_l9r_go_relaxed.owl	precorrin-6 methyltransferase|precorrin-6Y C5,15-methyltransferase (decarboxylating)|cobalt-precorrin 7 C15-methyltransferase activity|precorrin-6Y methylase				MetaCyc:RXN-8767|RHEA:34591									molecular_function											owl:Class	
GO:0047648	biolink:NamedThing	alkylamidase activity	Catalysis of the reaction: N-methylhexanamide + H(2)O = hexanoate + methylammonium.	tmpzr1t_l9r_go_relaxed.owl	N-methylhexanamide amidohydrolase activity				KEGG_REACTION:R03620|RHEA:20081|EC:3.5.1.39|MetaCyc:ALKYLAMIDASE-RXN									molecular_function											owl:Class	
GO:0018730	biolink:NamedThing	glutaconate CoA-transferase activity	Catalysis of the reaction: acetyl-CoA + (E)-glutaconate = acetate + glutaconyl-1-CoA.	tmpzr1t_l9r_go_relaxed.owl	acetyl-CoA:(E)-glutaconate CoA-transferase activity				MetaCyc:GLUTACONATE-COA-TRANSFERASE-RXN|EC:2.8.3.12|UM-BBD_reactionID:r0085|RHEA:23208									molecular_function											owl:Class	
GO:0071115	biolink:NamedThing	alpha5-beta1 integrin-endostatin complex	A protein complex that consists of an alpha5-beta1 integrin complex bound to endostatin, the NC1 domain of the alpha1 chain of type XVIII collagen.	tmpzr1t_l9r_go_relaxed.owl	ITGA5-ITGB1-CAL4A3 complex							mah	2009-11-13T02:18:57Z					cellular_component											owl:Class	
GO:0061596	biolink:NamedThing	3-sulfolactaldehyde reductase activity	Catalysis of the reaction 2,3-dihydroxypropane-1-sulfonate + NAD+ = 3-sulfolactaldehyde + NADH + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-15299|RHEA:40511|EC:1.1.1.373			dph	2014-02-10T10:09:43Z					molecular_function											owl:Class	
GO:1990644	biolink:NamedThing	microtubule site clamp	The binding activity of a molecule that attaches the spindle microtubules to the kinetochore.	tmpzr1t_l9r_go_relaxed.owl								vw	2015-02-13T15:50:13Z					molecular_function											owl:Class	
GO:0075508	biolink:NamedThing	entry of viral genome into host nucleus via retainment of capsid in nuclear pore complex and release of genome into nucleoplasm	Viral penetration into the host nucleus where a viral capsid enters the host nuclear pore complex (NPC) but remains attached to the pore on the nuclear side. The capsid then disassembles, releasing the viral genome into the nucleoplasm.	tmpzr1t_l9r_go_relaxed.owl	entry of viral genome into host nucleus via attachment of capsid to nuclear pore complex and release of genome into nucleoplasm					This mechanism is used by viruses such as Hepadnaviridae whose capsids enter the NPC but are too big to pass intact into the nucleus.		jl	2011-07-26T04:56:10Z					biological_process											owl:Class	
GO:0047867	biolink:NamedThing	dimethylmalate dehydrogenase activity	Catalysis of the reaction: (R)-3,3-dimethylmalate + NAD(+) = 3-methyl-2-oxobutanoate + CO(2) + NADH.	tmpzr1t_l9r_go_relaxed.owl	beta,beta-dimethylmalate dehydrogenase activity|(R)-3,3-dimethylmalate:NAD+ oxidoreductase (decarboxylating)				KEGG_REACTION:R01211|RHEA:13321|MetaCyc:DIMETHYLMALATE-DEHYDROGENASE-RXN|EC:1.1.1.84									molecular_function											owl:Class	
GO:1990838	biolink:NamedThing	poly(U)-specific exoribonuclease activity, producing 3' uridine cyclic phosphate ends	Catalysis of 3' exonucleolytic cleavage of poly(U), to form poly(U)-N containing a 3' uridine cyclic phosphate (U>P).	tmpzr1t_l9r_go_relaxed.owl								al	2015-08-26T10:24:51Z					molecular_function											owl:Class	
GO:0070073	biolink:NamedThing	clustering of voltage-gated calcium channels	The process in which voltage-gated calcium channels become localized together in high densities.	tmpzr1t_l9r_go_relaxed.owl	clustering of voltage-dependent calcium channels|clustering of voltage gated calcium channels|voltage-gated calcium channel clustering													biological_process											owl:Class	
GO:0071978	biolink:NamedThing	bacterial-type flagellum-dependent swarming motility	Bacterial-type flagellum-dependent cell motility in which the action of numerous flagella results in the smooth movement of a group of cells along a solid surface. Swarming motility is observed in groups of bacteria.	tmpzr1t_l9r_go_relaxed.owl	bacterial-type flagellum-mediated cell swarming|bacterial-type flagellar swarming motility							mah	2010-10-21T03:00:14Z					biological_process											owl:Class	
GO:0050439	biolink:NamedThing	2-hydroxy-3-oxoadipate synthase activity	Catalysis of the reaction: 2-oxoglutarate + glyoxylate + H(+) = 2-hydroxy-3-oxoadipate + CO(2).	tmpzr1t_l9r_go_relaxed.owl	oxoglutarate: glyoxylate carboligase activity|2-hydroxy-3-oxoadipate glyoxylate-lyase (carboxylating) activity|alpha-ketoglutaric-glyoxylic carboligase activity|2-oxoglutarate:glyoxylate succinaldehydetransferase (decarboxylating)|oxoglutarate:glyoxylate carboligase activity|2-hydroxy-3-oxoadipate synthetase activity				RHEA:14341|EC:2.2.1.5|KEGG_REACTION:R00474|MetaCyc:2-HYDROXY-3-OXOADIPATE-SYNTHASE-RXN									molecular_function											owl:Class	
GO:0008795	biolink:NamedThing	NAD+ synthase activity	Catalysis of the reaction: ATP + deamido-NAD+ + NH3 = AMP + diphosphate + NAD+.	tmpzr1t_l9r_go_relaxed.owl	diphosphopyridine nucleotide synthetase activity|NAD synthase activity|NAD(+) synthetase activity|nicotinamide adenine dinucleotide synthetase activity|deamido-NAD+:ammonia ligase (AMP-forming)|NAD synthase (AMP-forming)|NAD synthetase activity|NAD+ synthetase activity				EC:6.3.1.5|MetaCyc:NAD-SYNTH-NH3-RXN|RHEA:21188							GO:0008749|GO:0016965		molecular_function											owl:Class	
GO:0004120	biolink:NamedThing	photoreceptor cyclic-nucleotide phosphodiesterase activity	Catalysis of the reaction: nucleoside cyclic phosphate + H2O = nucleoside phosphate. This reaction is the hydrolysis of bonds in a cyclic nucleotide.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0102469	biolink:NamedThing	naringenin 2-hydroxylase activity	Catalysis of the reaction: (S)-naringenin + NADPH + O2 <=> 2-hydroxynaringenin + NADP + H2O.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-14069|RHEA:57588									molecular_function											owl:Class	
GO:0140591	biolink:NamedThing	nuclear envelope budding	The process by which large macromolecular complexes are budded through the inner nuclear membrane, into the perinuclear space, thus acquiring a membrane envelope. The enveloped particle fuses with the outer nuclear membrane and is released into the cytoplasm.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/20782						pg	2021-02-08T08:31:06Z					biological_process											owl:Class	
GO:0043424	biolink:NamedThing	protein histidine kinase binding	Binding to a protein histidine kinase.	tmpzr1t_l9r_go_relaxed.owl	histidine-protein kinase binding|protein-histidine kinase binding|histidine kinase binding													molecular_function											owl:Class	
GO:0008775	biolink:NamedThing	acetate CoA-transferase activity	Catalysis of the reaction: acyl-CoA + acetate = a fatty acid anion + acetyl-CoA.	tmpzr1t_l9r_go_relaxed.owl	acetyl-CoA:acetoacetate CoA transferase activity|acetate coenzyme A-transferase activity|acyl-CoA:acetate CoA-transferase activity|butyryl coenzyme A transferase activity|succinyl-CoA:acetate CoA transferase activity|butyryl CoA:acetate CoA transferase activity				EC:2.8.3.8|RHEA:13381|UM-BBD_enzymeID:e0012|MetaCyc:ACECOATRANS-RXN|Reactome:R-HSA-2066788									molecular_function											owl:Class	
GO:0036220	biolink:NamedThing	ITP diphosphatase activity	Catalysis of the reaction: ITP + H2O = IMP + diphosphate.	tmpzr1t_l9r_go_relaxed.owl	inosine-5'-triphosphate pyrophosphohydrolase activity				Reactome:R-HSA-2509827|KEGG_REACTION:R00720|MetaCyc:RXN0-6382|RHEA:29399			bf	2012-05-08T01:47:59Z					molecular_function											owl:Class	
GO:0016977	biolink:NamedThing	chitosanase activity	Catalysis of the endohydrolysis of beta-1,4-linkages between N-acetyl-D-glucosamine and D-glucosamine residues in a partly acetylated chitosan.	tmpzr1t_l9r_go_relaxed.owl	chitosan N-acetylglucosaminohydrolase activity				EC:3.2.1.132|MetaCyc:3.2.1.132-RXN									molecular_function											owl:Class	
GO:1990413	biolink:NamedThing	eyespot apparatus	A small pigmented organelle used in single-celled organisms to detect light.	tmpzr1t_l9r_go_relaxed.owl	eyespot|stigma							cjm	2014-07-03T21:26:24Z					cellular_component											owl:Class	
GO:0097072	biolink:NamedThing	interferon regulatory factor 3 complex	An interferon regulatory factor complex that consists of a homodimer of interferon regulatory factor 3.	tmpzr1t_l9r_go_relaxed.owl	IRF3:IRF3 complex							pr	2011-06-15T04:26:10Z					cellular_component											owl:Class	
GO:0004090	biolink:NamedThing	carbonyl reductase (NADPH) activity	Catalysis of the reaction: R-CHOH-R' + NADP+ = R-CO-R' + NADPH + H+.	tmpzr1t_l9r_go_relaxed.owl	NADPH2-dependent carbonyl reductase activity|aldehyde reductase I activity|aldehyde reductase 1|secondary-alcohol:NADP+ oxidoreductase activity|NADPH-dependent carbonyl reductase activity|prostaglandin 9-ketoreductase activity|xenobiotic ketone reductase activity|carbonyl reductase activity|ALR3|nonspecific NADPH-dependent carbonyl reductase activity				EC:1.1.1.184|RHEA:19257|Reactome:R-HSA-8937419|MetaCyc:CARBONYL-REDUCTASE-NADPH-RXN									molecular_function											owl:Class	
GO:0097409	biolink:NamedThing	glial cytoplasmic inclusion	Non-membrane-bound cytoplasmic inclusions composed of 10-40 nm granule-coated fibrils. These inclusions have an abnormal accumulation of alpha-synuclein protein and are found in association with multiple system atrophy.	tmpzr1t_l9r_go_relaxed.owl	GCI|Papp-Lantos body				NIF_Subcellular:nlx_subcell_20090703			pr	2012-10-31T13:55:11Z					cellular_component											owl:Class	
GO:0106386	biolink:NamedThing	(3R)-hydroxyacyl-CoA dehydrogenase (NAD) activity	Catalysis of the reaction: 3R-hydroxyacyl-CoA + NAD(+) = 3-oxoacyl-CoA + NADH.	tmpzr1t_l9r_go_relaxed.owl					EC:1.1.1.n12|RHEA:32711			hjd	2021-07-01T18:41:23Z					molecular_function											owl:Class	
GO:0071118	biolink:NamedThing	alphaV-beta3 integrin-NOV complex	A protein complex that consists of an alphaV-beta3 integrin complex bound to the extracellular matrix protein NOV.	tmpzr1t_l9r_go_relaxed.owl	ITGAV-ITGB3-FN-1-NOV complex							mah	2009-11-13T02:20:20Z					cellular_component											owl:Class	
GO:1990083	biolink:NamedThing	DnaA-Hda complex	A protein complex that inactivates the function of DnaA by inhibiting the phosphorylation of DnaA-ADP to DnaA-ATP and thereby preventing multiple events of replication initiation. In E. coli, this complex is composed of DnaA and Hda.	tmpzr1t_l9r_go_relaxed.owl								bhm	2013-04-30T11:49:04Z					cellular_component											owl:Class	
GO:0034530	biolink:NamedThing	4-hydroxymethylsalicyaldehyde dehydrogenase activity	Catalysis of the reaction: 4-hydroxymethylsalicylaldehyde + NAD+ + H2O = 4-hydroxymethylsalicylate + NADH + 2 H+.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0767|EC:1.2.1.-									molecular_function											owl:Class	
GO:0003320	biolink:NamedThing	heart rudiment involution	The inward folding of myocardial tissue derived from the right half of the heart rudiment that will form the future ventral part of the heart tube.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-10-27T09:29:24Z					biological_process											owl:Class	
GO:0097256	biolink:NamedThing	phenyllactate dehydrogenase activity	Catalysis of the reaction: (R)-3-phenyllactate + NAD+ = 3-phenylpyruvate + H+ + NADH.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/21412			RHEA:38351	This enzymatic activity is usually negligible, but may become prominent when phenylalanine levels are abnormally high as in the human disease phenylketonuria (PKU).		pr	2012-03-07T11:39:39Z					molecular_function											owl:Class	
GO:1902549	biolink:NamedThing	protein localization to Mei2 nuclear dot	A process in which a protein is transported to, or maintained in, a location within a Mei2 nuclear dot.	tmpzr1t_l9r_go_relaxed.owl	protein localization to Mei2 dot|protein localisation to Mei2 nuclear dot|protein localisation in Mei2 nuclear dot|protein localization in Mei2 nuclear dot							mah	2013-12-04T16:17:06Z					biological_process											owl:Class	
GO:0004107	biolink:NamedThing	chorismate synthase activity	Catalysis of the reaction: 5-O-(1-carboxyvinyl)-3-phosphoshikimate = chorismate + phosphate.	tmpzr1t_l9r_go_relaxed.owl	5-enolpyruvylshikimate-3-phosphate phospholyase activity|5-O-(1-carboxyvinyl)-3-phosphoshikimate phosphate-lyase (chorismate-forming)|5-O-(1-carboxyvinyl)-3-phosphoshikimate phosphate-lyase activity				KEGG_REACTION:R01714|MetaCyc:CHORISMATE-SYNTHASE-RXN|RHEA:21020|EC:4.2.3.5									molecular_function											owl:Class	
GO:0102497	biolink:NamedThing	scyllo-inositol dehydrogenase (NADP+) activity	Catalysis of the reaction: scyllo-inositol + NADP <=> 2,4,6/3,5-pentahydroxycyclohexanone + NADPH + H+.	tmpzr1t_l9r_go_relaxed.owl					RHEA:39063|MetaCyc:RXN-14347|EC:1.1.1.371									molecular_function											owl:Class	
GO:0070284	biolink:NamedThing	4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase activity	Catalysis of the reaction: 5-aminoimidazole ribonucleotide + S-adenosylmethionine = 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate + 5'deoxyadenosine.	tmpzr1t_l9r_go_relaxed.owl	ThiC|HMP-P synthase activity													molecular_function											owl:Class	
GO:0034545	biolink:NamedThing	fumarylpyruvate hydrolase activity	Catalysis of the reaction: fumarylpyruvate + H2O = fumarate + pyruvate + H+.	tmpzr1t_l9r_go_relaxed.owl					EC:3.7.1.20|UM-BBD_reactionID:r0811|RHEA:26168									molecular_function											owl:Class	
GO:0051451	biolink:NamedThing	myoblast migration	The orderly movement of a myoblast from one site to another, often during the development of a multicellular organism. A myoblast is a cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0005053	biolink:NamedThing	peroxisome matrix targeting signal-2 binding	Binding to a type 2 peroxisome targeting signal, a nonapeptide with a broad consensus sequence of (R/K)-(L/V/I)-(XXXXX)-(H/Q)-(L/A/F).	tmpzr1t_l9r_go_relaxed.owl	PTS2 binding|peroxisome targeting signal-2 binding|PTS2 receptor|PEX7|peroxisome targeting signal-2 receptor|peroxisomal targeting signal 2 (PTS2) binding													molecular_function											owl:Class	
GO:0106371	biolink:NamedThing	fluorescent chlorophyll catabolite monooxygenase (deformylase) activity	Catalysis of the reaction: O2 + primary fluorescent chlorophyll catabolite + reduced [NADPH--hemoprotein reductase] = formate + 2 H+ + oxidized [NADPH--hemoprotein reductase] + primary fluorescent dioxobilin-type chlorophyll catabolite.	tmpzr1t_l9r_go_relaxed.owl								hjd	2021-04-01T16:32:56Z					molecular_function											owl:Class	
GO:0047440	biolink:NamedThing	2-dehydro-3-deoxy-D-pentonate aldolase activity	Catalysis of the reaction: 2-dehydro-3-deoxy-D-arabinonate = glycolaldehyde + pyruvate.	tmpzr1t_l9r_go_relaxed.owl	3-deoxy-D-pentulosonic acid aldolase|2-keto-3-deoxy-D-pentonate aldolase activity|2-dehydro-3-deoxy-D-pentonate glycolaldehyde-lyase activity				MetaCyc:4.1.2.28-RXN|EC:4.1.2.28|RHEA:20609|KEGG_REACTION:R01782									molecular_function											owl:Class	
GO:0035062	biolink:NamedThing	omega speckle	A nucleoplasmic speckle distributed in the interchromatin space of cells in close proximity to chromatin. Omega speckles are distinct from interchromatin granules and contain heterogeneous nuclear RNA-binding proteins (hnRNPs).	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0042885	biolink:NamedThing	microcin B17 transport	The directed movement of microcin B17, a bactericidal peptide (antibiotic) produced by some enteric bacteria, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0052641	biolink:NamedThing	benzoic acid glucosyltransferase activity	Catalysis of the reaction: benzoic acid + UDP-glucose = benzoic acid glucose ester + UDP.	tmpzr1t_l9r_go_relaxed.owl	UDP:glucose:BA glucosyltransferase activity|UDP:glucose:benzoate glucosyltransferase activity|benzoate glucosyltransferase activity|UDP:glucose:benzoic acid glucosyltransferase activity				MetaCyc:RXN-11660									molecular_function											owl:Class	
GO:0102731	biolink:NamedThing	D-myo-inositol (1,3,4,6)-tetrakisphosphate 2-kinase activity	Catalysis of the reaction: myo-inositol 1,3,4,6-tetrakisphosphate(8-) + ATP = H+ + 1L-myo-inositol 1,2,3,4,6-pentakisphosphate(10-) + ADP.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-7185									molecular_function											owl:Class	
GO:2001066	biolink:NamedThing	amylopectin binding	Binding to amylopectin.	tmpzr1t_l9r_go_relaxed.owl								jl	2011-09-14T11:46:37Z					molecular_function											owl:Class	
GO:1901515	biolink:NamedThing	poly-beta-1,6-N-acetyl-D-glucosamine transmembrane transporter activity	Enables the transfer of poly-beta-1,6-N-acetyl-D-glucosamine from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-10-18T11:57:04Z					molecular_function											owl:Class	
GO:0033948	biolink:NamedThing	fructan beta-(2,1)-fructosidase activity	Catalysis of the hydrolysis of terminal, non-reducing (2->1) linked beta-D-fructofuranose residues in fructans.	tmpzr1t_l9r_go_relaxed.owl	1-fructan exohydrolase activity|1-FEH II|1-FEH w1|1-FEH w2|beta-(2,1)-D-fructan fructohydrolase activity|beta-(2,1)-linkage-specific fructan-beta-fructosidase activity|beta-(2,1)-fructan exohydrolase activity				MetaCyc:3.2.1.153-RXN|EC:3.2.1.153									molecular_function											owl:Class	
GO:0062116	biolink:NamedThing	phenyloplast	A chloroplast-derived plastid in which the solid form of phenol is stored.	tmpzr1t_l9r_go_relaxed.owl								dph	2019-03-15T11:57:05Z					cellular_component											owl:Class	
GO:0035663	biolink:NamedThing	Toll-like receptor 2 binding	Binding to a Toll-like 2 protein, a pattern recognition receptor that binds microbial pattern motifs to initiate an innate immune response.	tmpzr1t_l9r_go_relaxed.owl	TLR2 binding							bf	2011-02-01T10:21:51Z					molecular_function											owl:Class	
GO:0050306	biolink:NamedThing	sucrose 1F-fructosyltransferase activity	Catalysis of the reaction: 2 sucrose = D-glucose + 1F-beta-D-fructosylsucrose.	tmpzr1t_l9r_go_relaxed.owl	sucrose:sucrose 1F-beta-D-fructosyltransferase activity|sucrose:sucrose 1'-beta-D-fructosyltransferase activity|sucrose:sucrose 1(F)-beta-D-fructosyltransferase activity|sucrose:sucrose fructosyltransferase activity|SST activity|sucrose:sucrose 1-fructosyltransferase activity|sucrose 1(F)-fructosyltransferase activity|sucrose-sucrose 1-fructosyltransferase activity				RHEA:23312|EC:2.4.1.99|MetaCyc:SUCROSE-1F-FRUCTOSYLTRANSFERASE-RXN									molecular_function											owl:Class	
GO:0035355	biolink:NamedThing	Toll-like receptor 2-Toll-like receptor 6 protein complex	A heterodimeric protein complex containing Toll-like receptor 2 (TLR2) and Toll-like receptor 6 (TLR6).	tmpzr1t_l9r_go_relaxed.owl	TLR2-TLR6 protein complex|TLR2:TLR6 heterodimer|toll-like receptor TLR6:TLR2 heterodimeric complex|TLR6:TLR2 complex							bf	2010-03-04T04:37:00Z			GO:0038126		cellular_component											owl:Class	
GO:0007021	biolink:NamedThing	tubulin complex assembly	The aggregation and bonding together of alpha- and beta-tubulin to form a tubulin heterodimer.	tmpzr1t_l9r_go_relaxed.owl	tubulin-specific chaperone activity|tubulin folding|tubulin assembly													biological_process											owl:Class	
GO:0102274	biolink:NamedThing	glutathione S-conjugate carboxypeptidase activity	Catalysis of the reaction: H2O + a glutathione-toxin conjugate <=> glycine + a [Glu-Cys]-S-conjugate.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-12532									molecular_function											owl:Class	
GO:0048283	biolink:NamedThing	indeterminate inflorescence morphogenesis	The process in which the anatomical structures of determinate inflorescences are generated and organized. A determinate inflorescence is one that can produce an undefined number of floral meristems.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1904713	biolink:NamedThing	beta-catenin destruction complex binding	Binding to a beta-catenin destruction complex.	tmpzr1t_l9r_go_relaxed.owl	Axin-APC-beta-catenin-GSK3B complex binding|beta-catenin degradation complex binding|23S APC complex binding|APC-Axin-1-beta-catenin complex binding|BDC binding							bf	2015-10-05T14:34:14Z					molecular_function											owl:Class	
GO:0052809	biolink:NamedThing	acharan sulfate lyase activity	Catalysis of the cleavage of a carbon-oxygen bond in acharan sulfate, a glycosaminoglycan with a uniformly repeating disaccharide structure of alpha-D-N-acetylglucosaminyl-2-O-sulfo-alpha-L-iduronic acid.	tmpzr1t_l9r_go_relaxed.owl								ai	2011-09-26T02:58:28Z					molecular_function											owl:Class	
GO:0047679	biolink:NamedThing	arginine racemase activity	Catalysis of the reaction: L-arginine = D-arginine.	tmpzr1t_l9r_go_relaxed.owl					EC:5.1.1.9|RHEA:18069|MetaCyc:ARGININE-RACEMASE-RXN									molecular_function											owl:Class	
GO:0097097	biolink:NamedThing	nasal suture morphogenesis	The process in which the nasal suture is generated and organized.	tmpzr1t_l9r_go_relaxed.owl	internasal suture morphogenesis							pr	2011-07-05T03:09:04Z					biological_process											owl:Class	
GO:0051993	biolink:NamedThing	abscisic acid glucose ester beta-glucosidase activity	Catalysis of the reaction: abscisic acid glucose ester + H2O = abscisic acid + beta-D-glucose.	tmpzr1t_l9r_go_relaxed.owl	ABA-GE beta-glucosidase activity				EC:3.2.1.175|MetaCyc:RXN-11469|RHEA:31347			ai	2010-07-16T02:16:59Z					molecular_function											owl:Class	
GO:0018560	biolink:NamedThing	protocatechuate 3,4-dioxygenase type II activity	Catalysis of the reaction: 4-sulfocatechol + O2 = 3-sulfomuconate.	tmpzr1t_l9r_go_relaxed.owl					EC:1.13.11.-|UM-BBD_reactionID:r0581									molecular_function											owl:Class	
GO:0080176	biolink:NamedThing	xyloglucan 1,6-alpha-xylosidase activity	Catalysis of the hydrolysis of xyloglucan side chains so as to remove unsubstituted D-xylose residues attached to the glucose located at the non-reducing terminus.	tmpzr1t_l9r_go_relaxed.owl								dhl	2011-04-28T04:08:39Z					molecular_function											owl:Class	
GO:0106073	biolink:NamedThing	dolichyl pyrophosphate Glc2Man9GlcNAc2 alpha-1,2-glucosyltransferase activity	Catalysis of the addition of the third glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation; the transfer of glucose from dolichyl phosphate glucose (Dol-P-Glc) on to the lipid-linked oligosaccharide Glc(2)Man(9)GlcNAc(2)-PP-Dol.	tmpzr1t_l9r_go_relaxed.owl					EC:2.4.1.256|RHEA:29543			hjd	2017-11-28T19:16:37Z					molecular_function											owl:Class	
GO:0008502	biolink:NamedThing	melatonin receptor activity	Combining with melatonin, N-acetyl-5-methoxytryptamine, to initiate a change in cell activity. Melatonin is a neuroendocrine substance that stimulates the aggregation of melanosomes in melanophores, thus lightening the skin.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0110152	biolink:NamedThing	RNA NAD-cap (NAD-forming) hydrolase activity	Catalysis of the reaction: a 5'-end NAD(+)-phospho-ribonucleoside in mRNA + H2O = a 5'-end phospho-ribonucleoside in mRNA + H(+) + NAD(+).	tmpzr1t_l9r_go_relaxed.owl					RHEA:60880	This reaction specifically hydrolyzes the nicotinamide adenine dinucleotide (NAD) cap from a subset of RNAs by removing the entire NAD moiety from the 5'-end of an NAD-capped RNA.		kmv	2019-07-08T15:55:11Z					molecular_function											owl:Class	
GO:0008694	biolink:NamedThing	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity	Catalysis of the reaction: 3-octaprenyl-4-hydroxy benzoate = 2-octaprenylphenol + CO2.	tmpzr1t_l9r_go_relaxed.owl	3-polyprenyl 4-hydroxybenzoate decarboxylase activity|3-polyprenyl-4-hydroxybenzoate carboxy-lyase activity|UbiD|polyprenyl p-hydroxybenzoate decarboxylase activity|PPHB decarboxylase activity|3-octaprenyl-4-hydroxybenzoate decarboxylase activity|UbiX				MetaCyc:3-OCTAPRENYL-4-OHBENZOATE-DECARBOX-RXN|RHEA:27778|EC:4.1.1.98							GO:0019167		molecular_function											owl:Class	
GO:0098822	biolink:NamedThing	peptidyl-cysteine modification to L-cysteine persulfide	The modification of peptidyl-cysteine to form peptidyl-L-cysteine persulfide.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0269									biological_process											owl:Class	
GO:0019486	biolink:NamedThing	beta-alanine catabolic process to mevalonate semialdehyde, by transamination	The chemical reactions and pathways resulting in the breakdown of beta-alanine into other compounds, including mevalonate semialdehyde, by transamination.	tmpzr1t_l9r_go_relaxed.owl	beta-alanine degradation to mevalonate semialdehyde, by transamination|beta-alanine breakdown to mevalonate semialdehyde, by transamination				MetaCyc:BETA-ALA-DEGRADATION-I-PWY									biological_process											owl:Class	
GO:0060509	biolink:NamedThing	type I pneumocyte differentiation	The process in which a relatively unspecialized cell acquires specialized features of a type I pneumocyte. A type I pneumocyte is a flattened cell with greatly attenuated cytoplasm and a paucity of organelles.	tmpzr1t_l9r_go_relaxed.owl	small alveolar cell differentiation|squamous alveolar cell differentiation|membranous pneumocyte differentiation													biological_process											owl:Class	
GO:0031845	biolink:NamedThing	type 5 neuropeptide Y receptor binding	Binding to a type 5 neuropeptide Y receptor.	tmpzr1t_l9r_go_relaxed.owl	type 5 neuropeptide Y receptor ligand													molecular_function											owl:Class	
GO:0043426	biolink:NamedThing	MRF binding	Binding to Myogenic Regulatory Factor (MRF), a member of the basic Helix-Loop-Helix (bHLH) superfamily of transcription factors.	tmpzr1t_l9r_go_relaxed.owl	Mrf4 binding|Myf5 binding|MyoD binding|myogenin binding											GO:0051579|GO:0051576|GO:0051577|GO:0051578		molecular_function											owl:Class	
GO:0030305	biolink:NamedThing	heparanase activity	Catalysis of the cleavage of heparan sulfate; can degrade both heparan sulfate and heparin glycosaminoglycan chains.	tmpzr1t_l9r_go_relaxed.owl	heparinase activity				Reactome:R-HSA-1678694|Reactome:R-HSA-1667005									molecular_function											owl:Class	
GO:0097337	biolink:NamedThing	response to ziprasidone	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ziprasidone stimulus. Ziprasidone is a piperazine compound having 1,2-benzothiazol-3-yl- and 2-(6-chloro-1,3-dihydro-2-oxindol-5-yl)ethyl substituents attached to the nitrogen atoms.	tmpzr1t_l9r_go_relaxed.owl								pr	2012-06-12T11:05:31Z					biological_process											owl:Class	
GO:0052859	biolink:NamedThing	glucan endo-1,4-beta-glucosidase activity	Catalysis of the random hydrolysis of (1->4) linkages in (1->4)-beta-D-glucans.	tmpzr1t_l9r_go_relaxed.owl	beta-1->4-glucan hydrolase activity|endo-1,4-beta-D-glucanase activity|endo-1,4-beta-glucanase activity|1,4-beta-D-glucan glucanohydrolase activity|beta-1,4-glucan 4-glucanohydrolase activity|beta-1,4-glucanase activity|endo-(1,4)-beta-D-glucanase activity|endo-beta-1,4-glucanase activity|beta-1,4-glucan hydrolase activity|endo-(1->4)-beta-D-glucanase activity				EC:3.2.1.-			ai	2011-12-06T03:48:44Z					molecular_function											owl:Class	
GO:0106305	biolink:NamedThing	mannogen catabolic process	The chemical reactions and pathways resulting in the breakdown of mannogen, a mannose-containing polysaccharide that is a major energy reserve in Leishmania.	tmpzr1t_l9r_go_relaxed.owl	mannogen degradation|beta-1,2-mannan catabolism|mannogen catabolism|beta-1,2-mannan catabolic process|mannogen breakdown							hjd	2020-09-09T13:55:16Z					biological_process											owl:Class	
GO:0102345	biolink:NamedThing	3-hydroxy-lignoceroyl-CoA dehydratase activity	Catalysis of the reaction: (R)-3-hydroxylignoceroyl-CoA(4-) <=> trans-2-tetracosenoyl-CoA + H2O.	tmpzr1t_l9r_go_relaxed.owl					EC:4.2.1.134|MetaCyc:RXN-13304									molecular_function											owl:Class	
GO:0047436	biolink:NamedThing	arylmalonate decarboxylase activity	Catalysis of the reaction: 2-aryl-2-methylmalonate + H(+) = 2-arylpropionate + CO(2).	tmpzr1t_l9r_go_relaxed.owl	AMDase activity|2-aryl-2-methylmalonate carboxy-lyase activity|2-aryl-2-methylmalonate carboxy-lyase (2-arylpropanoate-forming)|AMDASE				EC:4.1.1.76|MetaCyc:4.1.1.76-RXN|KEGG_REACTION:R05173|RHEA:20513									molecular_function											owl:Class	
GO:0097100	biolink:NamedThing	supercoiled DNA binding	Binding to supercoiled DNA. For example, during replication and transcription, template DNA is negatively supercoiled in the receding downstream DNA and positively supercoiled in the approaching downstream DNA.	tmpzr1t_l9r_go_relaxed.owl								pr	2011-07-12T03:28:57Z					molecular_function											owl:Class	
GO:0043815	biolink:NamedThing	phosphoribosylglycinamide formyltransferase 2 activity	Catalysis of the reaction: formate + ATP + 5'-phospho-ribosylglycinamide = 5'-phosphoribosyl-N-formylglycinamide + ADP + diphosphate.	tmpzr1t_l9r_go_relaxed.owl	5'-phosphoribosylglycinamide transformylase 2|GART 2|formate-dependent GAR transformylase activity|GAR transformylase 2				RHEA:24829|MetaCyc:GARTRANSFORMYL2-RXN									molecular_function											owl:Class	
GO:1900018	biolink:NamedThing	phosphorylation of RNA polymerase II C-terminal domain serine 5 residues involved in recruitment of mRNA capping enzyme to RNA polymerase II holoenzyme complex	Any phosphorylation of RNA polymerase II C-terminal domain serine 5 residues that is involved in recruitment of mRNA capping enzyme to RNA polymerase II holoenzyme complex.	tmpzr1t_l9r_go_relaxed.owl								bf	2012-01-11T11:40:41Z					biological_process											owl:Class	
GO:0030926	biolink:NamedThing	calcium incorporation into metallo-oxygen cluster via bis-L-aspartato tris-L-glutamato L-histidino calcium tetramanganese tetroxide	The incorporation of calcium into a 4Mn-Ca-4O complex by bis-L-aspartato tris-L-glutamato L-histidino calcium tetramanganese tetroxide as in the photosystem II catalytic site.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0366									biological_process											owl:Class	
GO:0030925	biolink:NamedThing	calcium incorporation into metallo-oxygen cluster	The incorporation of calcium into a metallo-oxygen cluster.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0034861	biolink:NamedThing	benzothiazole-2-sulfonate hydrolase activity	Catalysis of the reaction: benzothiazole-2-sulfonate + H2O = 2-hydroxybenzothiazole + HSO3-.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r1290|EC:3.13.1.-									molecular_function											owl:Class	
GO:0061829	biolink:NamedThing	basal tubulobulbar complex	Actin-based structures involved in establishing the blood-testis barrier of the Sertoli cell.	tmpzr1t_l9r_go_relaxed.owl	basal TBC							dph	2017-01-15T10:42:31Z					cellular_component											owl:Class	
GO:0052593	biolink:NamedThing	tryptamine:oxygen oxidoreductase (deaminating) activity	Catalysis of the reaction: tryptamine + H2O + O2 = NH3 + indole acetaldehyde + hydrogen peroxide + H+.	tmpzr1t_l9r_go_relaxed.owl					KEGG_REACTION:R02173|MetaCyc:RXN-1401|EC:1.4.3.21									molecular_function											owl:Class	
GO:0000807	biolink:NamedThing	Z chromosome	The sex chromosome present in both sexes of species in which the female is the heterogametic sex. Two copies of the Z chromosome are present in each somatic cell of males and one copy is present in females.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:ZW_sex-determination_system									cellular_component											owl:Class	
GO:1903498	biolink:NamedThing	bundle sheath cell differentiation	The process in which a relatively unspecialized cell acquires the specialized features of a bundle sheath cell.	tmpzr1t_l9r_go_relaxed.owl								tb	2014-09-26T01:31:04Z					biological_process											owl:Class	
GO:0034682	biolink:NamedThing	integrin alphav-beta1 complex	An integrin complex that comprises one alphav subunit and one beta1 subunit.	tmpzr1t_l9r_go_relaxed.owl	ITGAV-ITGB1 complex|alphav-beta1 integrin complex													cellular_component											owl:Class	
GO:0008882	biolink:NamedThing	[glutamate-ammonia-ligase] adenylyltransferase activity	Catalysis of the reaction: ATP + [L-glutamate:ammonia ligase (ADP-forming)] = diphosphate + adenylyl-[L-glutamate:ammonia ligase (ADP-forming)].	tmpzr1t_l9r_go_relaxed.owl	ATP:[glutamate-ammonia-ligase] adenylyltransferase activity|adenosine triphosphate:glutamine synthetase adenylyltransferase activity|ATP:glutamine synthetase adenylyltransferase activity|glutamate-ammonia-ligase adenylyltransferase activity|glutamine-synthetase adenylyltransferase activity|ATP:L-glutamate:ammonia ligase (ADP-forming) adenylyltransferase activity				MetaCyc:GSADENYLATION-RXN|EC:2.7.7.42|RHEA:18589									molecular_function											owl:Class	
GO:0002485	biolink:NamedThing	antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent	The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class I protein complex following intracellular transport via a TAP-dependent ER pathway. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell and becomes associated with the MHC class I molecule in the ER following TAP-dependent transport from the cytosol. Class I here refers to classical class I molecules.	tmpzr1t_l9r_go_relaxed.owl	TAP-dependent antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway|TAP-dependent endogenous peptide antigen processing and presentation via MHC class I via ER pathway|endogenous peptide antigen processing and presentation via MHC class I via ER pathway, TAP-dependent													biological_process											owl:Class	
GO:0009544	biolink:NamedThing	chloroplast ATP synthase complex	The protein complex that catalyzes the phosphorylation of ADP to ATP in chloroplasts.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0047459	biolink:NamedThing	3-aminobutyryl-CoA ammonia-lyase activity	Catalysis of the reaction: (S)-3-aminobutanoyl-CoA = crotonoyl-CoA + NH(4)(+).	tmpzr1t_l9r_go_relaxed.owl	L-3-aminobutyryl-CoA deaminase activity|L-3-aminobutyryl-CoA ammonia-lyase activity|L-3-aminobutyryl-CoA ammonia-lyase (crotonoyl-CoA-forming)				MetaCyc:4.3.1.14-RXN|RHEA:10056|EC:4.3.1.14|KEGG_REACTION:R03030									molecular_function											owl:Class	
GO:0047103	biolink:NamedThing	3-alpha,7-alpha,12-alpha-trihydroxycholestan-26-al 26-oxidoreductase activity	Catalysis of the reaction: H2O + NAD+ + 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestan-26-al = NADH + 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanate.	tmpzr1t_l9r_go_relaxed.owl	3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-al dehydrogenase activity|cholestanetriol-26-al 26-dehydrogenase activity|3alpha,7alpha,12alpha-trihydroxycholestan-26-al 26-dehydrogenase activity|trihydroxydeoxycoprostanal dehydrogenase activity|3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-al:NAD+ 26-oxidoreductase activity|3-alpha,7-alpha,12-alpha-trihydroxycholestan-26-al 26-dehydrogenase activity|THAL-NAD oxidoreductase activity|3alpha,7alpha,12alpha-trihydroxycholestan-26-al 26-oxidoreductase activity				MetaCyc:1.2.1.40-RXN|RHEA:34627|EC:1.14.15.15									molecular_function											owl:Class	
GO:0008716	biolink:NamedThing	D-alanine-D-alanine ligase activity	Catalysis of the reaction: 2 D-alanine + ATP = D-alanyl-D-alanine + ADP + 2 H(+) + phosphate.	tmpzr1t_l9r_go_relaxed.owl	alanylalanine synthetase activity|alanine:alanine ligase (ADP-forming) activity|D-Ala-D-Ala synthetase activity|D-alanylalanine synthetase activity|D-alanine:D-alanine ligase (ADP-forming)|D-alanyl-D-alanine synthetase activity				RHEA:11224|EC:6.3.2.4|KEGG_REACTION:R01150|MetaCyc:DALADALALIG-RXN									molecular_function											owl:Class	
GO:0005523	biolink:NamedThing	tropomyosin binding	Binding to tropomyosin, a protein associated with actin filaments both in cytoplasm and, in association with troponin, in the thin filament of striated muscle.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0035657	biolink:NamedThing	eRF1 methyltransferase complex	A protein complex required for the methylation of a glutamine (Gln) residue in the protein release factor eRF1. In S. cerevisiae, this complex consists of at least Trm112p and Mtq2p.	tmpzr1t_l9r_go_relaxed.owl	eRF1 MTase complex							bf	2011-01-28T11:29:40Z					cellular_component											owl:Class	
GO:1901513	biolink:NamedThing	lipo-chitin oligosaccharide transmembrane transporter activity	Enables the transfer of lipo-chitin oligosaccharide from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-10-18T11:52:51Z					molecular_function											owl:Class	
GO:0140259	biolink:NamedThing	PRC1 complex binding	Binding to a PRC1 complex.	tmpzr1t_l9r_go_relaxed.owl								pg	2018-09-10T16:48:18Z					molecular_function											owl:Class	
GO:0002817	biolink:NamedThing	negative regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria	Any process that stops, prevents, or reduces the frequency, rate, or extent of biosynthesis of antibacterial peptides active against Gram-positive bacteria.	tmpzr1t_l9r_go_relaxed.owl	inhibition of biosynthetic process of antibacterial peptides active against Gram-positive bacteria|down regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria|downregulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria|down-regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria													biological_process											owl:Class	
GO:0071871	biolink:NamedThing	response to epinephrine	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an epinephrine stimulus. Epinephrine is a catecholamine that has the formula C9H13NO3; it is secreted by the adrenal medulla to act as a hormone, and released by certain neurons to act as a neurotransmitter active in the central nervous system.	tmpzr1t_l9r_go_relaxed.owl	response to adrenaline stimulus|response to epinephrine stimulus					Note that epinephrine and norepinephrine are ligands for the same receptors, and there are multiple adrenergic receptors.		mah	2010-09-13T03:27:48Z					biological_process											owl:Class	
GO:0070641	biolink:NamedThing	vitamin D4 metabolic process	The chemical reactions and pathways involving vitamin D4, (3S,5Z,7E)-9,10-secoergosta-5,7,10(19)-trien-3-ol.	tmpzr1t_l9r_go_relaxed.owl	vitamin D4 metabolism							mah	2009-05-08T02:33:01Z					biological_process											owl:Class	
GO:0047986	biolink:NamedThing	hydrogen-sulfide S-acetyltransferase activity	Catalysis of the reaction: acetyl-CoA + S(2-) = CoA + thioacetate.	tmpzr1t_l9r_go_relaxed.owl	hydrogen-sulphide S-acetyltransferase activity|acetyl-CoA:hydrogen-sulfide S-acetyltransferase activity|hydrogen-sulfide acetyltransferase activity				EC:2.3.1.10|RHEA:16625|MetaCyc:HYDROGEN-SULFIDE-S-ACETYLTRANSFERASE-RXN|KEGG_REACTION:R01850									molecular_function											owl:Class	
GO:0045027	biolink:NamedThing	DNA end binding	Binding to DNA ends exposed by the creation of double-strand breaks (DSBs).	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0071815	biolink:NamedThing	intermediate-density lipoprotein particle binding	Binding to a intermediate-density lipoprotein particle, a triglyceride-rich lipoprotein particle that typically contains APOB100, APOE and APOCs and has a density of 1.006-1.019 g/ml and a diameter of between 25-30 nm.	tmpzr1t_l9r_go_relaxed.owl	intermediate-density lipoprotein binding|IDL binding							mah	2010-09-06T04:28:35Z					molecular_function											owl:Class	
GO:0043287	biolink:NamedThing	poly(3-hydroxyalkanoate) binding	Binding to a poly(3-hydroxyalkanoate), a polyester of 3-hydroxyacids produced as intracellular granules by a large variety of bacteria.	tmpzr1t_l9r_go_relaxed.owl	PHA binding													molecular_function											owl:Class	
GO:0106324	biolink:NamedThing	(S)-limonene 1,2-monooxygenase NADH activity	Catalysis of the reaction: (4S)-limonene + NADH + H+ + O2 = NAD+ + H2O + (4S)-limonene-1,2-epoxide.	tmpzr1t_l9r_go_relaxed.owl					RHEA:26089			hjd	2020-09-23T15:35:58Z					molecular_function											owl:Class	
GO:0097023	biolink:NamedThing	fructose 6-phosphate aldolase activity	Catalysis of the reaction: D-fructose-6-phosphate = dihydroxyacetone + D-glyceraldehyde-3-phosphate.	tmpzr1t_l9r_go_relaxed.owl					RHEA:28002			pr	2011-03-29T04:54:05Z					molecular_function											owl:Class	
GO:0102170	biolink:NamedThing	5-epi-aristolochene-1,3-dihydroxylase activity	Catalysis of the reaction: (+)-5-epi-aristolochene + 2 NADPH + 2 H+ + 2 O2 <=> capsidiol + 2 NADP + 2 H2O.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-11908|EC:1.14.14.149|RHEA:28226									molecular_function											owl:Class	
GO:0005588	biolink:NamedThing	collagen type V trimer	A collagen heterotrimer containing type V alpha chains; [alpha1(V)]2alpha2(V) and alpha1(V)alpha2(V)alpha3(V) trimers have been observed; type V collagen triple helices associate to form fibrils.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0035910	biolink:NamedThing	ascending aorta morphogenesis	The process in which the anatomical structures of the ascending aorta are generated and organized. The ascending aorta is the portion of the aorta in a two-pass circulatory system that lies between the heart and the arch of aorta. In a two-pass circulatory system blood passes twice through the heart to supply the body once.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-06-24T11:14:52Z					biological_process											owl:Class	
GO:0090705	biolink:NamedThing	trichome papilla	A plant cell papilla that is part of a trichome cell.	tmpzr1t_l9r_go_relaxed.owl						Part of trichome cell (PO:0008030).		tb	2016-09-26T12:49:36Z					cellular_component											owl:Class	
GO:0034807	biolink:NamedThing	4,5-dihydroxybenzo(a)pyrene methyltransferase activity	Catalysis of the reaction: 4,5-dihydroxybenzo(a)pyrene + C1 unit = hydroxymethoxybenzo(a)pyrene.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r1131									molecular_function											owl:Class	
GO:0051430	biolink:NamedThing	corticotropin-releasing hormone receptor 1 binding	Binding to a corticotropin-releasing hormone receptor 1 (CRHR1). CRHR1 is the major subtype in the pituitary corticotroph, and mediates the stimulatory actions of corticotropin-releasing hormone on corticotropin hormone secretion. CRHR1 are also located in cortical areas of the brain, cerebellum and limbic system.	tmpzr1t_l9r_go_relaxed.owl	type 1 corticotropin releasing factor receptor ligand|type 1 corticotropin-releasing factor receptor binding|CRHR1 binding|type 1 corticotropin releasing factor receptor binding											GO:0031743		molecular_function											owl:Class	
GO:0052894	biolink:NamedThing	norspermine:oxygen oxidoreductase activity	Catalysis of the reaction: norspermine + oxygen + H2O = norspermidine + 3-aminopropanal + hydrogen peroxide.	tmpzr1t_l9r_go_relaxed.owl	norspermine oxidase activity				MetaCyc:RXN-10464|EC:1.5.3.16									molecular_function											owl:Class	
GO:0039673	biolink:NamedThing	evasion by virus of host dendritic cell activity	Any process by which a virus avoids the effects mediated by the host organism's dendritic cells.	tmpzr1t_l9r_go_relaxed.owl	modulation of host dendritic cell activity by virus|impairing dendritic cell function by virus|evasion by virus of host dendritic cell response							bf	2013-09-25T11:18:51Z					biological_process											owl:Class	
GO:0097514	biolink:NamedThing	sexual spore wall	A specialized envelope lying outside the cell membrane of a spore derived from a product of meiosis.	tmpzr1t_l9r_go_relaxed.owl								pr	2013-10-16T15:10:32Z					cellular_component											owl:Class	
GO:0033786	biolink:NamedThing	heptose-1-phosphate adenylyltransferase activity	Catalysis of the reaction: D-beta-D-heptose-1-phosphate + ATP = ADP-D-glycero-D-manno-heptose.	tmpzr1t_l9r_go_relaxed.owl	heptose 1-phosphate adenyltransferase activity|D-beta-D-heptose 1-phosphate adenylyltransferase activity				RHEA:27465|MetaCyc:RXN0-4342									molecular_function											owl:Class	
GO:0071666	biolink:NamedThing	Slit-Robo signaling complex	A protein-carbohydrate complex that consists of a transmembrane roundabout (Robo) receptor, an extracellular Slit ligand and heparin/heparan sulfate.	tmpzr1t_l9r_go_relaxed.owl	Slit-Robo signalling complex							mah	2010-02-12T03:35:28Z					cellular_component											owl:Class	
GO:0102423	biolink:NamedThing	(+)-sesaminol 2-O-glucosyltransferase activity	Catalysis of the reaction: (+)-sesaminol + UDP-alpha-D-glucose <=> (+)-sesaminol 2-O-beta-D-glucoside + UDP + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-13818									molecular_function											owl:Class	
GO:0106268	biolink:NamedThing	3,5-dichloro-THPH methyl transferase activity	Catalysis of the reaction: (3,5-dichloro-2,4,6-trihydroxyphenyl)hexan-1-one + S-adenosyl-L-methionine = 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one + H+ + S-adenosyl-L-homocysteine.	tmpzr1t_l9r_go_relaxed.owl	DIF-1 syntase				RHEA:48396			hjd	2020-06-02T18:25:03Z					molecular_function											owl:Class	
GO:0047615	biolink:NamedThing	actinomycin lactonase activity	Catalysis of the reaction: actinomycin + H2O = actinomycinic monolactone.	tmpzr1t_l9r_go_relaxed.owl	actinomycin lactonohydrolase activity				MetaCyc:ACTINOMYCIN-LACTONASE-RXN|EC:3.1.1.39									molecular_function											owl:Class	
GO:0016492	biolink:NamedThing	G protein-coupled neurotensin receptor activity	Combining with the tridecapeptide neurotensin to initiate a G-protein mediated change in cell activity. A G-protein is a signal transduction molecule that alternates between an inactive GDP-bound and an active GTP-bound state.	tmpzr1t_l9r_go_relaxed.owl	neurotensin receptor activity, G protein coupled|G-protein coupled neurotensin receptor activity|neurotensin receptor activity, G-protein coupled|G protein coupled neurotensin receptor activity													molecular_function											owl:Class	
GO:0044067	biolink:NamedThing	modification by symbiont of host intercellular junctions	The process in which a symbiont organism effects a change in the structure or function of its host intercellular junction, a specialized region of connection between two cells.	tmpzr1t_l9r_go_relaxed.owl	modification of host intercellular junctions by symbiont													biological_process											owl:Class	
GO:0070852	biolink:NamedThing	cell body fiber	A neuron projection that is found in unipolar neurons and corresponds to the region between the cell body and the point at which the single projection branches.	tmpzr1t_l9r_go_relaxed.owl	cell body fibre|primary neurite							mah	2009-08-11T04:38:53Z					cellular_component											owl:Class	
GO:0047054	biolink:NamedThing	berbamunine synthase activity	Catalysis of the reaction: (S)-N-methylcoclaurine + (R)-N-methylcoclaurine + [reduced NADPH--hemoprotein reductase] + O2 <=> berbamunine + [oxidized NADPH--hemoprotein reductase] + 2 H2O.	tmpzr1t_l9r_go_relaxed.owl	heme-thiolate	https://github.com/geneontology/go-ontology/issues/21133			RHEA:23576|EC:1.14.19.66|MetaCyc:1.1.3.34-RXN									molecular_function											owl:Class	
GO:0042256	biolink:NamedThing	mature ribosome assembly	The aggregation, arrangement and bonding together of the large and small ribosomal subunits into a functional ribosome.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0018491	biolink:NamedThing	2-oxobutyrate synthase activity	Catalysis of the reaction: 2-oxobutanoate + CoA + oxidized ferredoxin = propanoyl-CoA + CO2 + reduced ferredoxin.	tmpzr1t_l9r_go_relaxed.owl	2-oxobutyrate-ferredoxin oxidoreductase activity|alpha-ketobutyrate synthase activity|alpha-ketobutyrate-ferredoxin oxidoreductase activity|2-oxobutanoate:ferredoxin 2-oxidoreductase (CoA-propionylating)|2-ketobutyrate synthase activity				UM-BBD_reactionID:r0358|RHEA:32135|MetaCyc:2-OXOBUTYRATE-SYNTHASE-RXN									molecular_function											owl:Class	
GO:0061788	biolink:NamedThing	EGF repeat binding	Binding to Epidermal Growth Factor (EGF) repeats.	tmpzr1t_l9r_go_relaxed.owl	Epidermal Growth Factor repeat binding|Epidermal growth factor domain binding							dph	2016-09-08T15:22:28Z					molecular_function											owl:Class	
GO:0006385	biolink:NamedThing	transcription elongation from RNA polymerase III promoter	The extension of an RNA molecule after transcription initiation and promoter clearance at an RNA polymerase III promoter by the addition of ribonucleotides catalyzed by RNA polymerase III.	tmpzr1t_l9r_go_relaxed.owl	RNA elongation from Pol III promoter|RNA polymerase III transcription elongation factor activity													biological_process											owl:Class	
GO:0102446	biolink:NamedThing	rhamnetin 3-O-methyltransferase activity	Catalysis of the reaction: rhamnetin + S-adenosyl-L-methionine  <=> 3',4',5-trihydroxy-3,7-dimethoxyflavone + S-adenosyl-L-homocysteine  + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-13932									molecular_function											owl:Class	
GO:0072688	biolink:NamedThing	SHREC complex localization	Any process in which a SHREC complex is transported to, or maintained in, a specific location.	tmpzr1t_l9r_go_relaxed.owl	SHREC complex localisation|establishment and maintenance of SHREC complex localization							mah	2011-07-20T12:51:49Z					biological_process											owl:Class	
GO:0018789	biolink:NamedThing	cyclamate sulfohydrolase activity	Catalysis of the reaction: cyclohexylsulfamate + H(2)O = cyclohexylamine + sulfate.	tmpzr1t_l9r_go_relaxed.owl	cyclamate sulfamatase activity|cyclamate sulphohydrolase activity|cyclamate sulfamidase activity|cyclohexylsulfamate sulfamidase activity|cyclohexylsulfamate sulfohydrolase activity				MetaCyc:CYCLAMATE-SULFOHYDROLASE-RXN|UM-BBD_reactionID:r0755|EC:3.10.1.2|RHEA:18481|KEGG_REACTION:R02564									molecular_function											owl:Class	
GO:0004699	biolink:NamedThing	calcium-independent protein kinase C activity	Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein. This reaction requires diacylglycerol but not calcium.	tmpzr1t_l9r_go_relaxed.owl	calcium-independent PKC activity|novel protein kinase C activity				Reactome:R-HSA-5607740									molecular_function											owl:Class	
GO:0052806	biolink:NamedThing	sulfite reductase (coenzyme F420) activity	Catalysis of the reaction: sulfite + 3 1,5-dihydrocoenzyme F420 = hydrogen sulfide + 3 H2O + 3 coenzyme F420. 1,5-dihydrocoenzyme F420 is also known as reduced coenzyme F420.	tmpzr1t_l9r_go_relaxed.owl	sulfite:reduced coenzyme F420 reductase activity|coenzyme F420-dependent sulfite reductase activity|coenzyme F420-sulfite reductase activity|hydrogen-sulfide:coenzyme F420 oxidoreductase activity							ai	2011-09-22T04:08:13Z					molecular_function											owl:Class	
GO:0019386	biolink:NamedThing	methanogenesis, from carbon dioxide	The chemical reactions and pathways resulting in the formation of methane, a colorless, odorless, flammable gas with the formula CH4, from other compounds, including carbon dioxide (CO2).	tmpzr1t_l9r_go_relaxed.owl	methane biosynthesis from carbon dioxide|methane biosynthetic process from carbon dioxide				MetaCyc:METHANOGENESIS-PWY									biological_process											owl:Class	
GO:1990589	biolink:NamedThing	ATF4-CREB1 transcription factor complex	Transcription factor complex consisting of ATF4 and CREB1 subunits that is capable of binding to cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3') as part of the positive regulation of transcription. Regulatory targets include the GRP78 (HSPA5) promoter in humans, whose activation by this complex is part of the ER stress response pathway.	tmpzr1t_l9r_go_relaxed.owl								bhm	2014-12-15T14:22:44Z					cellular_component											owl:Class	
GO:0007220	biolink:NamedThing	Notch receptor processing	The series of successive proteolytic cleavages of the Notch protein, which result in an active form of the receptor.	tmpzr1t_l9r_go_relaxed.owl	N receptor processing													biological_process											owl:Class	
GO:0030270	biolink:NamedThing	formylmethanofuran-tetrahydromethanopterin N-formyltransferase activity	Catalysis of the reaction: 5,6,7,8-tetrahydromethanopterin + N-formylmethanofuran + H(+) = N(5)-formyl-5,6,7,8-tetrahydromethanopterin + methanofuran.	tmpzr1t_l9r_go_relaxed.owl	formylmethanofuran:5,6,7,8-tetrahydromethanopterin N5-formyltransferase activity|FTR|formylmethanofuran:5,6,7,8-tetrahydromethanopterin 5-formyltransferase activity|formylmethanofuran-tetrahydromethanopterin formyltransferase activity|N-formylmethanofuran(CHO-MFR):tetrahydromethanopterin(H4MPT) formyltransferase activity|formylmethanofuran:tetrahydromethanopterin formyltransferase activity				MetaCyc:2.3.1.101-RXN|KEGG_REACTION:R03390|UM-BBD_reactionID:r0346|RHEA:18061|EC:2.3.1.101							GO:0018714		molecular_function											owl:Class	
GO:0102343	biolink:NamedThing	3-hydroxy-arachidoyl-CoA dehydratase activity	Catalysis of the reaction: (R)-3-hydroxyicosanoyl-CoA <=> trans-2-icosenoyl-CoA + H2O.	tmpzr1t_l9r_go_relaxed.owl					EC:4.2.1.134|MetaCyc:RXN-13302									molecular_function											owl:Class	
GO:0004034	biolink:NamedThing	aldose 1-epimerase activity	Catalysis of the reaction: alpha-D-glucose = beta-D-glucose. Also acts on L-arabinose, D-xylose, D-galactose, maltose and lactose.	tmpzr1t_l9r_go_relaxed.owl	mutarotase activity|aldose mutarotase activity				RHEA:10264|MetaCyc:ALDOSE-1-EPIMERASE-RXN|EC:5.1.3.3									molecular_function											owl:Class	
GO:1990226	biolink:NamedThing	histone methyltransferase binding	Binding to a histone methyltransferase enzyme.	tmpzr1t_l9r_go_relaxed.owl								pr	2013-11-07T11:59:58Z					molecular_function											owl:Class	
GO:0043429	biolink:NamedThing	2-nonaprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity	Catalysis of the reaction: 2-nonaprenyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-methionine = 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-homocysteine.	tmpzr1t_l9r_go_relaxed.owl	2-nonaprenyl-6-methoxy-1,4-benzoquinone methylase activity					Note that the polyprenyl sidechain substrate for these methyltransferases varies in length between species, for example, 6 units in S. cerevisiae, 8 units in E. coli and 10 units in G. suboxidans. Where the length of the substrate polyprenyl chain is unknown, the term '2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity ; GO:0008425' should be used.								molecular_function											owl:Class	
GO:0120095	biolink:NamedThing	vacuole-isolation membrane contact site	An organelle membrane contact site formed at the junction of the vacuolar membrane and the isolation membrane or phagophore in response to starvation or other stresses, leading to the formation of the autophagosome.	tmpzr1t_l9r_go_relaxed.owl	VICS|vacuole-IM contact site|vacuole-phagophore contact site							krc	2017-09-18T20:01:35Z					cellular_component											owl:Class	
GO:0071084	biolink:NamedThing	alpha2-beta1 integrin-CD47 complex	A protein complex that consists of an alpha2-beta1 integrin complex bound to the cell surface protein CD47.	tmpzr1t_l9r_go_relaxed.owl	ITGA2-ITGB1-CD47 complex							mah	2009-11-06T04:44:35Z					cellular_component											owl:Class	
GO:0010180	biolink:NamedThing	thioglucosidase binding	Binding to a thioglucosidase enzyme.	tmpzr1t_l9r_go_relaxed.owl	myrosinase binding													molecular_function											owl:Class	
GO:0009326	biolink:NamedThing	formate dehydrogenase complex	An enzyme complex that catalyzes the dehydrogenation of formate to produce carbon dioxide (CO2).	tmpzr1t_l9r_go_relaxed.owl					EC:1.17.1.9									cellular_component											owl:Class	
GO:0050344	biolink:NamedThing	trans-cinnamate 2-monooxygenase activity	Catalysis of the reaction: trans-cinnamate + H(+) + NADPH + O(2) = 2-coumarate + H(2)O + NADP(+).	tmpzr1t_l9r_go_relaxed.owl	trans-cinnamate,NADPH:oxygen oxidoreductase (2-hydroxylating)|trans-cinnamic acid 2-hydroxylase activity|cinnamic acid 2-hydroxylase activity|cinnamate 2-hydroxylase activity|cinnamic 2-hydroxylase activity|cinnamate 2-monooxygenase activity				MetaCyc:TRANS-CINNAMATE-2-MONOOXYGENASE-RXN|EC:1.14.13.14|RHEA:10956|KEGG_REACTION:R02254									molecular_function											owl:Class	
GO:0002305	biolink:NamedThing	CD8-positive, gamma-delta intraepithelial T cell differentiation	The process in which a precursor cell type acquires the specialized features of a CD8-positive, gamma-delta intraepithelial T cell. Intraepithelial T cells are found among epithelial cells in mucosal areas and have distinct phenotypes and developmental pathways.	tmpzr1t_l9r_go_relaxed.owl	CD8-positive, gamma-delta intraepithelial T lymphocyte differentiation|CD8-positive, gamma-delta intraepithelial T-cell differentiation|CD8-positive, gamma-delta intraepithelial T cell development|CD8-positive, gamma-delta intraepithelial T-lymphocyte differentiation					Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.								biological_process											owl:Class	
GO:0015861	biolink:NamedThing	cytidine transport	The directed movement of cytidine, cytosine riboside, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0033114	biolink:NamedThing	cyanelle thylakoid lumen	The volume enclosed by a cyanelle thylakoid membrane.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0090531	biolink:NamedThing	L-ascorbic acid biosynthetic process via GDP-alpha-D-mannose	The chemical reactions and pathways resulting in the formation of L-ascorbic acid via the intermediate GDP-alpha-D-mannose.	tmpzr1t_l9r_go_relaxed.owl	L-ascorbic acid biosynthesis via GDP-alpha-D-mannose|Smirnoff-Wheeler's pathway				BioCyc:PWY-882			tb	2013-02-06T15:31:01Z					biological_process											owl:Class	
GO:1903701	biolink:NamedThing	substantia propria of cornea development	The process whose specific outcome is the progression of a substantia propria of cornea over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl	stroma of cornea development|substantia propria development|corneal stroma development							cls	2014-12-03T13:12:09Z					biological_process											owl:Class	
GO:0034528	biolink:NamedThing	2-carboxy-2-hydroxy-8-carboxychromene isomerase activity	Catalysis of the reaction: 2-carboxy-2-hydroxy-8-carboxychromene = 2-hydroxy-3-carboxybenzalpyruvate.	tmpzr1t_l9r_go_relaxed.owl					EC:5.3.99.-|UM-BBD_reactionID:r0791									molecular_function											owl:Class	
GO:0030445	biolink:NamedThing	yeast-form cell wall	The wall surrounding a cell of a dimorphic fungus growing in the single-cell budding yeast form, in contrast to the filamentous or hyphal form.	tmpzr1t_l9r_go_relaxed.owl						See also the Fungal Anatomy Ontology term 'vegetative cell ; FAO:0000032'.								cellular_component											owl:Class	
GO:0004574	biolink:NamedThing	oligo-1,6-glucosidase activity	Catalysis of the hydrolysis of (1->6)-alpha-D-glucosidic linkages in some oligosaccharides produced from starch and glycogen by alpha-amylase, and in isomaltose. Releases a free alpha-D-glucose.	tmpzr1t_l9r_go_relaxed.owl	limit dextrinase|oligosaccharide alpha-1,6-glucohydrolase activity|alpha-limit dextrinase activity|exo-oligo-1,6-glucosidase activity|oligosaccharide alpha-1,6-glucosidase activity|dextrin 6alpha-glucanohydrolase activity|alpha-methylglucosidase activity|sucrase-isomaltase activity|dextrin 6-glucanohydrolase activity|isomaltase activity				EC:3.2.1.10|MetaCyc:3.2.1.10-RXN									molecular_function											owl:Class	
GO:0089713	biolink:NamedThing	Cbf1-Met4-Met28 complex	A heteromeric complex consisting of Cbf1 and basic leucine zipper (bZIP) containing transcriptional activators, Met4 and Met28, that forms over the sequence TCACGTG in the upstream activating sequence (UAS) of genes involved in sulfur amino acid metabolism, resulting in their transcriptional activation.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0070037	biolink:NamedThing	rRNA (pseudouridine) methyltransferase activity	Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a pseudouridine residue in an rRNA molecule.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-6790906									molecular_function											owl:Class	
GO:0030269	biolink:NamedThing	tetrahydromethanopterin S-methyltransferase activity	Catalysis of the reaction: 5-methyltetrahydromethanopterin + coenzyme M = 5,6,7,8-tetrahydromethanopterin + methyl-coenzyme M. 2-(methylthio)ethanesulfonate is also known as methyl-CoM.	tmpzr1t_l9r_go_relaxed.owl	N5-methyltetrahydromethanopterin--coenzyme M methyltransferase activity|5-methyl-5,6,7,8-tetrahydromethanopterin:2-mercaptoethanesulfonate 2-methyltransferase activity|N(5)-methyltetrahydromethanopterin--coenzyme M methyltransferase activity|tetrahydromethanopterin methyltransferase activity				UM-BBD_reactionID:r0355|KEGG_REACTION:R04347|MetaCyc:2.1.1.86-RXN|EC:2.1.1.86|RHEA:53492							GO:0018709		molecular_function											owl:Class	
GO:0015433	biolink:NamedThing	ABC-type peptide antigen transporter activity	Catalysis of the reaction: peptide antigen(in) + ATP = peptide antigen(out) + ADP + phosphate.	tmpzr1t_l9r_go_relaxed.owl	major histocompatibility peptide transporter activity|peptide antigen ABC transporter|peptide antigen transporter activity|ATP-dependent peptide antigen transmembrane transporter activity|ATPase-coupled peptide antigen transmembrane transporter activity|peptide antigen-transporting ATPase activity				Reactome:R-HSA-983144|TC:3.A.1.209.1|Reactome:R-HSA-1236949									molecular_function											owl:Class	
GO:0140509	biolink:NamedThing	epithelium-like organization	The organization of a polarized cell layer during morphogenesis in protozoa; an example is found during culmination in D. discoideum, involving alpha and beta catenins.	tmpzr1t_l9r_go_relaxed.owl								pg	2020-08-28T07:29:53Z					biological_process											owl:Class	
GO:0043896	biolink:NamedThing	glucan 1,6-alpha-glucosidase activity	Catalysis of the hydrolysis of (1->6)-alpha-D-glucosidic linkages in (1->6)-alpha-D-glucans and derived oligosaccharides.	tmpzr1t_l9r_go_relaxed.owl	glucodextrinase|exo-1,6-beta-glucosidase|glucan alpha-1,6-D-glucohydrolase activity|exo-1,6-alpha-glucosidase activity|glucodextranase activity|glucan-1,6-alpha-glucosidase activity				MetaCyc:3.2.1.70-RXN|EC:3.2.1.70									molecular_function											owl:Class	
GO:0005109	biolink:NamedThing	frizzled binding	Binding to a frizzled (fz) receptor.	tmpzr1t_l9r_go_relaxed.owl	frizzled-2 ligand|fz ligand|frizzled ligand|frizzled-2 binding|fz2 binding|fz2 ligand|fz binding											GO:0005110		molecular_function											owl:Class	
GO:0003189	biolink:NamedThing	aortic valve formation	The developmental process pertaining to the initial formation of the aortic valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-10-08T01:05:44Z					biological_process											owl:Class	
GO:0052872	biolink:NamedThing	tocotrienol omega-hydroxylase activity	Catalysis of the reaction: tocotrienol + O2 + NADPH + H+ = 13'-hydroxy-tocotrienol + NADP+ + H2O .	tmpzr1t_l9r_go_relaxed.owl	tocotrienol 13-hydroxylase activity				EC:1.14.13.-			ai	2012-01-30T03:07:27Z					molecular_function											owl:Class	
GO:0140068	biolink:NamedThing	histone crotonyltransferase activity	Catalysis of the reaction: crotonyl-CoA + histone = CoA + crotonyl-histone.	tmpzr1t_l9r_go_relaxed.owl								pg	2017-07-20T16:55:16Z					molecular_function											owl:Class	
GO:0047570	biolink:NamedThing	3-oxoadipate enol-lactonase activity	Catalysis of the reaction: 3-oxoadipate enol-lactone + H2O = 3-oxoadipate.	tmpzr1t_l9r_go_relaxed.owl	beta-ketoadipic enol-lactone hydrolase activity|3-ketoadipate enol-lactonase activity|4-carboxymethylbut-3-en-4-olide enol-lactonohydrolase activity|3-oxoadipic enol-lactone hydrolase activity|beta-ketoadipate enol-lactone hydrolase activity|carboxymethylbutenolide lactonase activity				MetaCyc:3-OXOADIPATE-ENOL-LACTONASE-RXN|RHEA:10184|EC:3.1.1.24									molecular_function											owl:Class	
GO:0018615	biolink:NamedThing	2-indanone monooxygenase activity	Catalysis of the reaction: 2-indanone + NADPH + 1/2 O2 = NADP+ + 3-isochromanone.	tmpzr1t_l9r_go_relaxed.owl					EC:1.14.12.-|UM-BBD_reactionID:r0424									molecular_function											owl:Class	
GO:0050062	biolink:NamedThing	long-chain-fatty-acyl-CoA reductase activity	Catalysis of the reaction: a long-chain aldehyde + CoA + NADP+ = a long-chain acyl-CoA + NADPH.	tmpzr1t_l9r_go_relaxed.owl	acyl coenzyme A reductase activity|long-chain fatty acyl-CoA reductase activity|long-chain-aldehyde:NADP+ oxidoreductase (acyl-CoA-forming)|long-chain fatty acyl CoA reductase activity				EC:1.2.1.50|MetaCyc:LONG-CHAIN-FATTY-ACYL-COA-REDUCTASE-RXN|RHEA:15437									molecular_function											owl:Class	
GO:0002105	biolink:NamedThing	endonucleolytic cleaveage between LSU-rRNA and 4.5S rRNA of tetracistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 4.5S-rRNA, 5S-rRNA)	Endonucleolytic cleavage between the LSU-rRNA and the 4.5S rRNA of an rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, Large Subunit (LSU) the 4.5S rRNA, and the 5S rRNA in that order from 5' to 3' along the primary transcript. Note that the use of the word tetracistronic refers only to the number of mature rRNA molecules which will be produced from the primary transcript and ignores tRNAs that may also be present within the primary transcript.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0030773	biolink:NamedThing	6-hydroxymellein O-methyltransferase activity	Catalysis of the reaction: 6-hydroxymellein + S-adenosyl-L-methionine = 6-methoxymellein + S-adenosyl-L-homocysteine + H(+).	tmpzr1t_l9r_go_relaxed.owl	6-hydroxymellein methyltransferase activity|S-adenosyl-L-methionine:6-hydroxymellein 6-O-methyltransferase activity				RHEA:15201|MetaCyc:6-HYDROXYMELLEIN-O-METHYLTRANSFERASE-RXN|KEGG_REACTION:R03934|EC:2.1.1.108									molecular_function											owl:Class	
GO:0030289	biolink:NamedThing	protein phosphatase 4 complex	A protein serine/threonine phosphatase complex formed by the catalytic subunit of protein phosphatase 4 plus one or more regulatory subunits.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0002528	biolink:NamedThing	regulation of vascular permeability involved in acute inflammatory response	Any process that modulates the extent to which blood vessels can be pervaded by fluid contributing to an acute inflammatory response.	tmpzr1t_l9r_go_relaxed.owl	regulation of vascular permeability during acute inflammatory response													biological_process											owl:Class	
GO:0003114	biolink:NamedThing	positive regulation of heart rate by circulating norepinephrine	The process in which the secretion of norepinephrine into the bloodstream increases the rate of heart muscle contraction.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of heart rate by circulating noradrenaline													biological_process											owl:Class	
GO:0102282	biolink:NamedThing	3-ketodihydrosphinganine (C18) reductase activity	Catalysis of the reaction: NAD(1-) + a sphinganine <=> 3-dehydrosphinganinium(1+) + NADH + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-12641									molecular_function											owl:Class	
GO:0036299	biolink:NamedThing	non-recombinational interstrand cross-link repair	Removal of a DNA interstrand crosslink (a covalent attachment of DNA bases on opposite strands of the DNA) and restoration of the DNA by a mechanism that does not involve homologous DNA recombination.	tmpzr1t_l9r_go_relaxed.owl	recombination-independent ICL repair|recombination-independent interstrand cross-link repair							bf	2012-08-07T11:11:59Z					biological_process											owl:Class	
GO:0140575	biolink:NamedThing	transmembrane monodehydroascorbate reductase activity	Oxidation of monodehydroascorbate outside of a membrane coupled to the reduction of L-ascorbate to monodehydro-L-ascorbate radical on the inner side of a membrane. Electrons get transferred across the membrane during the reaction.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/20602			RHEA:66524			pg	2021-01-07T16:20:04Z					molecular_function											owl:Class	
GO:0106143	biolink:NamedThing	tRNA (m7G46) methyltransferase complex	A protein complex involved in the catalysis of the formation of the modified nucleotide 7-methylguanine (at position 46 in certain tRNAs, such as tRNA(phe) and tRNA(met). In yeast, it is a heterotetramer of two subunits, Trm8 (catalytic) and Trm82 (WD repeat).	tmpzr1t_l9r_go_relaxed.owl	tRNA m7G methylation complex|Trm8-Trm82 complex|tRNA (m7G46) methyltransferase							hjd	2018-09-07T14:53:29Z					cellular_component											owl:Class	
GO:0000405	biolink:NamedThing	bubble DNA binding	Binding to DNA segment that contains a bubble. A bubble occurs when DNA contains a region of unpaired, single-stranded DNA flanked on both sides by regions of paired, double-stranded DNA.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0071460	biolink:NamedThing	cellular response to cell-matrix adhesion	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of cell-matrix adhesion.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-12-17T02:25:45Z					biological_process											owl:Class	
GO:0106237	biolink:NamedThing	arachidonate 12(R)-lipoxygenase activity	Catalysis of the reaction: arachidonate + O(2)=(5Z,8Z,10E,12R,14Z)-12-hydroperoxyicosa-5,8,10,14-tetraenoate.	tmpzr1t_l9r_go_relaxed.owl					RHEA:41336			hjd	2019-12-18T21:03:02Z					molecular_function											owl:Class	
GO:0050240	biolink:NamedThing	pyrogallol 1,2-oxygenase activity	Catalysis of the reaction: O(2) + pyrogallol = (Z)-5-oxohex-2-enedioate + 2 H(+).	tmpzr1t_l9r_go_relaxed.owl	pyrogallol 1,2-dioxygenase activity|1,2,3-trihydroxybenzene:oxygen 1,2-oxidoreductase (decyclizing)				EC:1.13.11.35|MetaCyc:PYROGALLOL-12-OXYGENASE-RXN|KEGG_REACTION:R03246|RHEA:19673									molecular_function											owl:Class	
GO:0050177	biolink:NamedThing	phenylpyruvate decarboxylase activity	Catalysis of the reaction: phenylpyruvate = phenylacetaldehyde + CO2.	tmpzr1t_l9r_go_relaxed.owl	phenylpyruvate carboxy-lyase activity|phenylpyruvate carboxy-lyase (phenylacetaldehyde-forming)				MetaCyc:PHENYLPYRUVATE-DECARBOXYLASE-RXN|EC:4.1.1.43|RHEA:14185									molecular_function											owl:Class	
GO:0102906	biolink:NamedThing	7-epi-alpha-selinene synthase activity	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate(3-) <=> (-)-7-epi-alpha-selinene + diphosphoric acid.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-8609|EC:4.2.3.86|RHEA:30383									molecular_function											owl:Class	
GO:0045018	biolink:NamedThing	retrograde transport, vacuole to Golgi	The directed movement of substances from the vacuole to the trans-Golgi network; this occurs in yeast via the prevacuolar/endosomal compartment.	tmpzr1t_l9r_go_relaxed.owl	retrograde transport from the vacuole													biological_process											owl:Class	
GO:0033211	biolink:NamedThing	adiponectin-activated signaling pathway	A series of molecular signals initiated by the binding of adiponectin to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.	tmpzr1t_l9r_go_relaxed.owl	adiponectin-mediated signaling pathway|adipocytokine signaling pathway|adiponectin-mediated signalling pathway													biological_process											owl:Class	
GO:0033430	biolink:NamedThing	CGC codon-amino acid adaptor activity	A triplet codon-amino acid adaptor activity that recognizes a CGC codon.	tmpzr1t_l9r_go_relaxed.owl	arginine tRNA					Note that in the standard genetic code, CGC codes for arginine.								molecular_function											owl:Class	
GO:0006877	biolink:NamedThing	cellular cobalt ion homeostasis	Any process involved in the maintenance of an internal steady state of cobalt ions at the level of a cell.	tmpzr1t_l9r_go_relaxed.owl	cobalt homeostasis													biological_process											owl:Class	
GO:0047536	biolink:NamedThing	2-aminoadipate transaminase activity	Catalysis of the reaction: 2-oxoglutarate + L-2-aminoadipate = 2-oxoadipate + L-glutamate.	tmpzr1t_l9r_go_relaxed.owl	alpha-aminoadipate aminotransferase activity|2-aminoadipate aminotransferase activity|L-2-aminoadipate:2-oxoglutarate aminotransferase activity|2-aminoadipic aminotransferase activity|glutamic-ketoadipic transaminase activity|glutamate-alpha-ketoadipate transaminase activity				RHEA:12601|Reactome:R-HSA-508561|EC:2.6.1.39|Reactome:R-HSA-70952|KEGG_REACTION:R01939|MetaCyc:2-AMINOADIPATE-AMINOTRANSFERASE-RXN									molecular_function											owl:Class	
GO:0047071	biolink:NamedThing	3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione 4,5-dioxygenase activity	Catalysis of the reaction: 3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione + O(2) = 3-hydroxy-5,9,17-trioxo-4,5:9,10-disecoandrosta-1(10),2-dien-4-oate + H(+).	tmpzr1t_l9r_go_relaxed.owl	3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione:oxygen 4,5-oxidoreductase (decyclizing)|steroid 4,5-dioxygenase activity|3-alkylcatechol 2,3-dioxygenase activity				MetaCyc:1.13.11.25-RXN|RHEA:21352|UM-BBD_reactionID:r1151|KEGG_REACTION:R04597|EC:1.13.11.25									molecular_function											owl:Class	
GO:0050064	biolink:NamedThing	luteolin 7-O-glucuronosyltransferase activity	Catalysis of the reaction: luteolin + UDP-alpha-D-glucuronate = luteolin 7-O-beta-D-glucosiduronate + UDP.	tmpzr1t_l9r_go_relaxed.owl	luteolin 7-O-glucoronosyltransferase activity|uridine diphosphoglucuronate-luteolin 7-O-glucuronosyltransferase activity|UDPglucuronate:luteolin 7-O-glucuronosyltransferase activity|UDP-glucuronate:luteolin 7-O-glucuronosyltransferase activity|LGT				MetaCyc:LUTEOLIN-7-O-GLUCORONOSYLTRANSFERASE-RXN|KEGG_REACTION:R03589|RHEA:10568|EC:2.4.1.189									molecular_function											owl:Class	
GO:1901761	biolink:NamedThing	oxytetracycline metabolic process	The chemical reactions and pathways involving oxytetracycline.	tmpzr1t_l9r_go_relaxed.owl	oxytetracycline metabolism							yaf	2013-01-15T09:52:50Z					biological_process											owl:Class	
GO:0102426	biolink:NamedThing	myricetin-3-O-glucoside 1,6-glucosyltransferase activity	Catalysis of the reaction: myricetin 3-O-beta-D-glucopyranoside + UDP-alpha-D-glucose <=> myricetin 3-O-gentiobioside + UDP + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-13823									molecular_function											owl:Class	
GO:0050441	biolink:NamedThing	3-ethylmalate synthase activity	Catalysis of the reaction: butanoyl-CoA + glyoxylate + H(2)O = 3-ethylmalate + CoA + H(+).	tmpzr1t_l9r_go_relaxed.owl	3-ethylmalate glyoxylate-lyase (CoA-butanoylating) activity|2-ethyl-3-hydroxybutanedioate synthase activity|butanoyl-CoA:glyoxylate C-butanoyltransferase (thioester-hydrolysing, 1-carboxypropyl-forming)				EC:2.3.3.7|RHEA:10500|MetaCyc:3-ETHYLMALATE-SYNTHASE-RXN|KEGG_REACTION:R01180									molecular_function											owl:Class	
GO:0090067	biolink:NamedThing	regulation of thalamus size	Any process that modulates the size of the thalamus. The thalamus is a part of the diencephalon that is composed of the dorsal thalamus and the ventral thalamus.	tmpzr1t_l9r_go_relaxed.owl								tb	2009-09-02T11:03:03Z					biological_process											owl:Class	
GO:0036291	biolink:NamedThing	protein cis-autophosphorylation	The phosphorylation by a protein of one or more of its own amino acid residues.	tmpzr1t_l9r_go_relaxed.owl	cis-autophosphorylation							bf	2012-07-18T10:27:06Z					biological_process											owl:Class	
GO:0050138	biolink:NamedThing	nicotinate dehydrogenase activity	Catalysis of the reaction: H(2)O + NADP(+) + nicotinate = 6-hydroxynicotinate + H(+) + NADPH.	tmpzr1t_l9r_go_relaxed.owl	nicotinate hydroxylase activity|nicotinate:NADP+ 6-oxidoreductase (hydroxylating)|nicotinic acid hydroxylase activity				MetaCyc:RXN-7637|KEGG_REACTION:R01720|EC:1.17.1.5|MetaCyc:NICOTINATE-DEHYDROGENASE-RXN|RHEA:12236									molecular_function											owl:Class	
GO:0034432	biolink:NamedThing	bis(5'-adenosyl)-pentaphosphatase activity	Catalysis of the reaction: P1-P6-bis(5'-adenosyl) pentaphosphate + H2O = AMP + adenosine 5'-tetraphosphate.	tmpzr1t_l9r_go_relaxed.owl	Ap5a pyrophosphohydrolase activity|AP-5-A hydrolase activity|AP5A hydrolase activity|diadenosine 5',5'''-P1,P6-pentaphosphate hydrolase activity|AP(5)A hydrolase activity													molecular_function											owl:Class	
GO:0140623	biolink:NamedThing	type I pilus assembly	The assembly from its constituent parts of a type I pilus.	tmpzr1t_l9r_go_relaxed.owl	type I fimbrium assembly|type I fimbria assembly|type I fimbrial biogenesis|type I fimbrial assembly|T1P assembly|type I fimbriae biogenesis|type 1 pilus biogenesis|type I fimbrium biogenesis|type I fimbria biogenesis|type I fimbriae assembly	https://github.com/geneontology/go-ontology/issues/14469						pg	2021-03-10T12:23:20Z					biological_process											owl:Class	
GO:0000286	biolink:NamedThing	alanine dehydrogenase activity	Catalysis of the reaction: L-alanine + H2O + NAD+ = pyruvate + NH3 + NADH + H(+).	tmpzr1t_l9r_go_relaxed.owl	NAD-dependent alanine dehydrogenase activity|NAD-linked alanine dehydrogenase activity|alanine oxidoreductase activity|L-alanine dehydrogenase activity|L-alanine:NAD+ oxidoreductase (deaminating)|AlaDH|alpha-alanine dehydrogenase activity|NADH-dependent alanine dehydrogenase activity				RHEA:18405|EC:1.4.1.1|MetaCyc:ALANINE-DEHYDROGENASE-RXN									molecular_function											owl:Class	
GO:0044204	biolink:NamedThing	host cell nuclear matrix	The dense fibrillar network lying on the inner side of the host nuclear membrane.	tmpzr1t_l9r_go_relaxed.owl								jl	2009-10-21T11:15:36Z					cellular_component											owl:Class	
GO:0043129	biolink:NamedThing	surfactant homeostasis	Any process involved in the maintenance of a steady-state level of the surface-active lipoprotein mixture which coats the alveoli.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0004800	biolink:NamedThing	thyroxine 5'-deiodinase activity	Catalysis of the reaction: 3,5,3'-L-triiodo-L-thyronine + iodide + acceptor + H+ = L-thyroxine + donor-H2.	tmpzr1t_l9r_go_relaxed.owl	acceptor:3,5,3'-triiodo-L-thyronine oxidoreductase (iodinating)|thyroxine deiodinase activity|outer ring-deiodinating pathway|diiodothyronine 5'-deiodinase activity|type II iodothyronine deiodinase activity|thyroxine 5' deiodinase activity|type I iodothyronine deiodinase activity|iodothyronine outer ring monodeiodinase activity|iodothyronine 5'-deiodinase activity|L-thyroxine iodohydrolase (reducing) activity				Reactome:R-HSA-350869|EC:1.21.99.4|MetaCyc:THYROXINE-DEIODINASE-RXN|Reactome:R-HSA-209772|RHEA:19745	Note that this was EC:3.8.1.4.								molecular_function											owl:Class	
GO:0047328	biolink:NamedThing	acyl-phosphate-hexose phosphotransferase activity	Catalysis of the reaction: D-hexose + acyl phosphate = D-hexose phosphate + an acid.	tmpzr1t_l9r_go_relaxed.owl	hexose phosphate:hexose phosphotransferase activity|acyl-phosphate:D-hexose phosphotransferase activity				EC:2.7.1.61|MetaCyc:2.7.1.61-RXN|RHEA:13077									molecular_function											owl:Class	
GO:0018127	biolink:NamedThing	NAD(P)-serine ADP-ribosyltransferase activity	Catalysis of the reaction: NAD(P)+ + L-serine = nicotinamide + N2-(ADP-D-ribosyl)-L-serine.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0034892	biolink:NamedThing	endosulfan lactone lactonase activity	Catalysis of the reaction: endosulfan lactone + H2O = endosulfan hydroxycarboxylate + H+.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r1389									molecular_function											owl:Class	
GO:0050524	biolink:NamedThing	coenzyme-B sulfoethylthiotransferase activity	Catalysis of the reaction: coenzyme B + methyl-coenzyme M = coenzyme M-coenzyme B heterodisulfide + methane. Methyl-CoM is also known as 2-(methylthio)ethanesulfonate, coenzyme B as N-(7-mercaptoheptanoyl)threonine 3-O-phosphate, and coenzyme M-coenzyme B heterodisulfide as CoM-S-S-CoB.	tmpzr1t_l9r_go_relaxed.owl	methyl-coenzyme-M reductase activity|2-(methylthio)ethanesulfonate:N-(7-thioheptanoyl)-3-O-phosphothreonine S-(2-sulfoethyl)thiotransferase activity|methyl-CoM reductase activity|coenzyme-B sulphoethylthiotransferase activity|methyl coenzyme M reductase activity				RHEA:12532|MetaCyc:METHYL-COM-HTP-RXN|KEGG_REACTION:R04541|UM-BBD_reactionID:r0356|EC:2.8.4.1							GO:0018552		molecular_function											owl:Class	
GO:0022828	biolink:NamedThing	phosphorylation-gated channel activity	Enables the transmembrane transfer of a solute by a channel that opens in response to phosphorylation of one of its constituent parts.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0102495	biolink:NamedThing	GA5 3beta-hydroxylase activity	Catalysis of the reaction: gibberellin A5 + O2 + 2-oxoglutarate <=> gibberellin A3 + succinate + carbon dioxide.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-14318									molecular_function											owl:Class	
GO:0006316	biolink:NamedThing	movement of group I intron	Lateral transfer of a group I intron to a homologous allele that lacks the intron, mediated by a site-specific endonuclease encoded within the mobile intron; group I introns are self-splicing introns that use guanosine as a cofactor in the splicing reaction.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0102566	biolink:NamedThing	1-acyl dihydroxyacetone phosphate reductase activity	Catalysis of the reaction: 1-oleoylglycerone 3-phosphate + NADPH + H+ = 1-oleoyl-sn-glycero-3-phosphate + NADP.	tmpzr1t_l9r_go_relaxed.owl					EC:1.1.1.101|MetaCyc:RXN-15046									molecular_function											owl:Class	
GO:0047181	biolink:NamedThing	tetrahydroxybenzophenone synthase activity	Catalysis of the reaction: 3-hydroxybenzoyl-CoA + 3 malonyl-CoA = 3 CO2 + 2,3',4,6-tetrahydroxybenzophenone + 4 coenzyme A.	tmpzr1t_l9r_go_relaxed.owl	malonyl-CoA:3-hydroxybenzoyl-CoA malonyltransferase activity				MetaCyc:2.3.1.151-RXN|RHEA:19305|EC:2.3.1.151									molecular_function											owl:Class	
GO:0033837	biolink:NamedThing	anthocyanin 3'-O-beta-glucosyltransferase activity	Catalysis of the reaction: UDP-glucose + an anthocyanin = UDP + an anthocyanin 3'-O-beta-D-glucoside.	tmpzr1t_l9r_go_relaxed.owl	UDP-glucose:anthocyanin 3'-O-beta-D-glucosyltransferase activity|UDP-glucose:anthocyanin 3'-O-glucosyltransferase activity|3'GT				RHEA:35627|EC:2.4.1.238|MetaCyc:2.4.1.238-RXN									molecular_function											owl:Class	
GO:0071045	biolink:NamedThing	nuclear histone mRNA catabolic process	The chemical reactions and pathways resulting in the breakdown of histone messenger RNA (mRNA) within the nucleus.	tmpzr1t_l9r_go_relaxed.owl								krc	2009-07-30T09:52:44Z					biological_process											owl:Class	
GO:0008873	biolink:NamedThing	gluconate 2-dehydrogenase activity	Catalysis of the reaction: D-gluconate + NADP+ = 2-dehydro-D-gluconate + NADPH + H+.	tmpzr1t_l9r_go_relaxed.owl	2-keto-D-gluconate reductase activity|D-gluconate:NADP+ oxidoreductase activity|2-ketogluconate reductase activity				RHEA:16653|EC:1.1.1.215|MetaCyc:1.1.1.215-RXN									molecular_function											owl:Class	
GO:0046989	biolink:NamedThing	galactosyl beta-1,3 N-acetylgalactosamine beta-1,3-glucuronosyltransferase activity	Catalysis of the transfer, in a beta 1,3 linkage, of D-glucuronic acid (GlcUA) from UDP-GlcUA to the disaccharide galactosyl beta-1,3 N-acetylgalactosamine, a common component of glycoproteins and glycolipids.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0034821	biolink:NamedThing	citronellol dehydrogenase activity	Catalysis of the reaction: citronellol + NAD+ = citronellal + NADH + H+.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r1155									molecular_function											owl:Class	
GO:0018628	biolink:NamedThing	terephthalate 1,2-dioxygenase activity	Catalysis of the reaction: H(+) + NADH + O(2) + terephthalate = (3S,4R)-3,4-dihydroxycyclohexa-1,5-diene-1,4-dicarboxylate + NAD(+).	tmpzr1t_l9r_go_relaxed.owl	1,4-dicarboxybenzoate 1,2-dioxygenase activity|benzene-1,4-dicarboxylate,NADH:oxygen oxidoreductase (1,2-hydroxylating)|benzene-1,4-dicarboxylate 1,2-dioxygenase activity				MetaCyc:1.14.12.15-RXN|UM-BBD_reactionID:r0150|KEGG_REACTION:R05148|EC:1.14.12.15|RHEA:10312									molecular_function											owl:Class	
GO:0018407	biolink:NamedThing	peptidyl-thyronine iodination to form 3',3'',5'-triiodo-L-thyronine	The iodination of peptidyl-thyronine to form peptidyl-3',3'',5'-triiodo-L-thyronine (triiodothyronine).	tmpzr1t_l9r_go_relaxed.owl	peptidyl-thyronine iodination to form triiodothyronine				RESID:AA0177									biological_process											owl:Class	
GO:0071067	biolink:NamedThing	alphav-beta3 integrin-ADAM23 complex	A protein complex that consists of an alphav-beta3 integrin complex bound to the transmembrane metallopeptidase ADAM23.	tmpzr1t_l9r_go_relaxed.owl	ITGAV-ITGB3-ADAM23 complex							mah	2009-11-03T04:04:40Z					cellular_component											owl:Class	
GO:0033941	biolink:NamedThing	mannan exo-1,2-1,6-alpha-mannosidase activity	Catalysis of the hydrolysis of (1->2)-alpha-D- and (1->6)-alpha-D- linkages in mannan, releasing D-mannose.	tmpzr1t_l9r_go_relaxed.owl	exo-1,2-1,6-alpha-mannosidase activity|1,2-1,6-alpha-D-mannan D-mannohydrolase activity				MetaCyc:3.2.1.137-RXN|EC:3.2.1.137									molecular_function											owl:Class	
GO:0005252	biolink:NamedThing	open rectifier potassium channel activity	Enables the transmembrane transfer of a potassium ion by an open rectifier voltage-gated channel. An open rectifier current-voltage relationship is one in which the direction of rectification depends on the external potassium ion concentration.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0036128	biolink:NamedThing	CatSper complex	A sperm-specific voltage-gated calcium channel that controls the intracellular calcium ion concentration and, thereby, the swimming behavior of sperm. Consists of a heteromeric tetramer surrounding a calcium ion- selective pore. May also contain additional auxiliary subunits.	tmpzr1t_l9r_go_relaxed.owl	CatSper channel complex|CATSPER channel							bf	2012-03-02T10:26:48Z					cellular_component											owl:Class	
GO:0004533	biolink:NamedThing	exoribonuclease H activity	Catalysis of the exonucleolytic cleavage of RNA to 5'-phosphomonoester oligonucleotides in both 5' to 3' and 3' to 5' directions.	tmpzr1t_l9r_go_relaxed.owl	retroviral reverse transcriptase RNaseH				EC:3.1.13.2|MetaCyc:3.1.13.2-RXN									molecular_function											owl:Class	
GO:0014871	biolink:NamedThing	cross bridge formation involved in regulation of the velocity of shortening in skeletal muscle contraction	The process in which actin and myosin interact, split ATP and generate force during skeletal muscle contraction. This process is one of the components of the regulation of the force of skeletal muscle contraction.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0071857	biolink:NamedThing	beta-endorphin receptor binding	Binding to a beta-endorphin receptor.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-09-10T03:23:01Z					molecular_function											owl:Class	
GO:1905660	biolink:NamedThing	mitotic checkpoint complex assembly	The aggregation, arrangement and bonding together of a set of components to form a mitotic checkpoint complex.	tmpzr1t_l9r_go_relaxed.owl	mitotic checkpoint complex formation|MCC assembly|MCC formation							mah	2016-11-09T14:17:41Z					biological_process											owl:Class	
GO:0097138	biolink:NamedThing	BAD-BCL-2 complex	A heterodimeric protein complex consisting of BAD and BCL-2, members of the Bcl-2 family of anti- and proapoptotic regulators.	tmpzr1t_l9r_go_relaxed.owl								pr	2011-08-02T01:37:50Z					cellular_component											owl:Class	
GO:0035447	biolink:NamedThing	mycothiol synthase activity	Catalysis of the reaction: 1-D-myo-inosityl-2-L-cysteinylamido-2-deoxy-alpha-D-glucopyranoside + acetyl-CoA = mycothiol + coenzyme A + H+. Mycothiol is also known as AcCys-GlcN-Ins and 1-D-myo-inosityl-2-L-cysteinylamido-2-deoxy-alpha-D-glucopyranoside as Cys-GlcN-Ins or desacetylmycothiol.	tmpzr1t_l9r_go_relaxed.owl	acetyl-CoA:Cys-GlcN-Ins acetyltransferase				MetaCyc:MONOMER-9684			bf	2010-04-14T11:40:26Z					molecular_function											owl:Class	
GO:0030570	biolink:NamedThing	pectate lyase activity	Catalysis of the reaction: a pectate = a pectate + a pectate oligosaccharide with 4-(4-deoxy-alpha-D-galact-4-enuronosyl)-D-galacturonate end. This reaction is the eliminative cleavage of pectate to give oligosaccharides with 4-deoxy-alpha-D-gluc-4-enuronosyl groups at their non-reducing ends.	tmpzr1t_l9r_go_relaxed.owl	alpha-1,4-D-endopolygalacturonic acid lyase activity|polygalacturonic acid lyase activity|pectic acid transeliminase activity|endo-alpha-1,4-polygalacturonic acid lyase activity|pectate transeliminase activity|polygalacturonate lyase activity|PGA lyase activity|endopectin methyltranseliminase activity|pectin trans-eliminase activity|polygalacturonic transeliminase activity|pectic acid lyase activity|(1->4)-alpha-D-galacturonan lyase activity|endogalacturonate transeliminase activity|pectic lyase activity|polygalacturonic acid trans-eliminase activity|PPase-N activity				EC:4.2.2.2|MetaCyc:4.2.2.2-RXN									molecular_function											owl:Class	
GO:0050179	biolink:NamedThing	phenylserine aldolase activity	Catalysis of the reaction: L-threo-3-phenylserine = benzaldehyde + glycine.	tmpzr1t_l9r_go_relaxed.owl	L-threo-3-phenylserine benzaldehyde-lyase (glycine-forming)|L-threo-3-phenylserine benzaldehyde-lyase activity				MetaCyc:PHENYLSERINE-ALDOLASE-RXN|EC:4.1.2.26|RHEA:21712|KEGG_REACTION:R01766									molecular_function											owl:Class	
GO:0106084	biolink:NamedThing	mitotic nuclear membrane microtubule tethering complex	A protein complex capable of interacting with the spindle pole body and the nuclear envelope, in order to embed the spindle pole body in the nuclear envelope at fusion sites of the inner and outer nuclear membrane.	tmpzr1t_l9r_go_relaxed.owl	nuclear membrane mitotic spindle pole body tethering complex|Mps2-Bbp1-Spc29 complex	https://github.com/geneontology/go-ontology/issues/14829				In S. cerevisae Mps2-Bpb1 is the membrane anchor sub complex and Spc29 is the spindle pole body linker molecule.		hjd	2018-01-05T19:55:37Z					cellular_component											owl:Class	
GO:0033870	biolink:NamedThing	thiol sulfotransferase activity	Catalysis of the reaction: 3'-phosphoadenylyl sulfate + a thiol = adenosine 3',5'-bisphosphate + an S-alkyl thiosulfate.	tmpzr1t_l9r_go_relaxed.owl	adenosine 3'-phosphate 5'-sulphatophosphate sulfotransferase activity|3'-phosphoadenylyl-sulfate:thiol S-sulfotransferase activity|PAPS sulfotransferase activity				RHEA:14637|MetaCyc:THIOL-SULFOTRANSFERASE-RXN|EC:2.8.2.16									molecular_function											owl:Class	
GO:0097099	biolink:NamedThing	structural constituent of albumen	The action of a molecule that contributes to the structural integrity of albumen (also called egg white). Albumen is the clear liquid contained within an egg and consists of water and proteins, among which are ovomucin and ovomucoid. It protects the egg yolk and provides additional nutrition for the growth of the embryo.	tmpzr1t_l9r_go_relaxed.owl	structural constituent of egg white							pr	2011-07-07T02:12:51Z					molecular_function											owl:Class	
GO:1990320	biolink:NamedThing	collagen type XXI trimer	A collagen homotrimer of alpha1(XXI) chains; type XXI collagen triple helices found in the extracellular matrix component of blood vessel walls and in the cytoplasm of cultured human aortic smooth muscle.	tmpzr1t_l9r_go_relaxed.owl								bhm	2014-03-14T16:40:14Z					cellular_component											owl:Class	
GO:0102338	biolink:NamedThing	3-oxo-lignoceronyl-CoA synthase activity	Catalysis of the reaction: behenoyl-CoA(4-) + malonyl-CoA(5-) + H+ <=> 3-oxotetracosanoyl-CoA. + carbon dioxide + coenzyme A.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-13297|RHEA:36507									molecular_function											owl:Class	
GO:0043781	biolink:NamedThing	cobalt-factor II C20-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + cobalt-factor II = S-adenosyl-L-homocysteine + cobalt-factor III.	tmpzr1t_l9r_go_relaxed.owl	CbiL|cobalt-factor II C20 methyltransferase activity|cobalt-precorrin-2 C(20)-methyltransferase activity|S-adenosyl-L-methionine:cobalt-factor-II C20-methyltransferase activity				EC:2.1.1.151|RHEA:17997|MetaCyc:RXN-8760									molecular_function											owl:Class	
GO:0050565	biolink:NamedThing	aerobactin synthase activity	Catalysis of the reaction: 2 N(6)-acetyl-N(6)-hydroxy-L-lysine + 4 ATP + citrate + 2 H(2)O = 4 ADP + aerobactin + 8 H(+) + 4 phosphate.	tmpzr1t_l9r_go_relaxed.owl	citrate:N6-acetyl-N6-hydroxy-L-lysine ligase (ADP-forming)|citrate:6-N-acetyl-6-N-hydroxy-L-lysine ligase (ADP-forming)				MetaCyc:6.3.2.27-RXN|RHEA:11760|KEGG_REACTION:R04357									molecular_function											owl:Class	
GO:0102523	biolink:NamedThing	2-chloroacrylate reductase activity	Catalysis of the reaction: (S)-2-chloropropanoate + NADP <=> 2-chloroacrylate + NADPH + H+.	tmpzr1t_l9r_go_relaxed.owl					EC:1.3.1.103|RHEA:36591|MetaCyc:RXN-14536									molecular_function											owl:Class	
GO:0102618	biolink:NamedThing	oryzalexin B synthase activity	Catalysis of the reaction: oryzalexin D + NAD(P) <=> oryzalexin B + H+ + NAD(P)H.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-15466									molecular_function											owl:Class	
GO:0052901	biolink:NamedThing	spermine:oxygen oxidoreductase (spermidine-forming) activity	Catalysis of the reaction: H(2)O + O(2) + spermine = 3-aminopropanal + H(2)O(2) + spermidine.	tmpzr1t_l9r_go_relaxed.owl	N(1)-acetylpolyamine oxidase activity|polyamine oxidase activity|spermine oxidase activity|non-specific polyamine oxidase activity				RHEA:25804|MetaCyc:RXN-9015|EC:1.5.3.13|MetaCyc:1.5.3.17-RXN|EC:1.5.3.16|EC:1.5.3.17|Reactome:R-HSA-141341|KEGG_REACTION:R09076									molecular_function											owl:Class	
GO:0036343	biolink:NamedThing	psychomotor behavior	The specific behavior of an organism that combines cognitive functions and physical movement. For example, driving a car, throwing a ball, or playing a musical instrument.	tmpzr1t_l9r_go_relaxed.owl								bf	2012-09-11T14:32:06Z					biological_process											owl:Class	
GO:0034909	biolink:NamedThing	6-hydroxypseudooxynicotine dehydrogenase activity	Catalysis of the reaction: 6-hydroxypseudooxynicotine + H2O + OH- = 6-hydroxy-3-succinoylpyridine + 4 H+ + 4 e- + methylamine.	tmpzr1t_l9r_go_relaxed.owl					RHEA:34223|EC:1.5.99.14|UM-BBD_reactionID:r1441									molecular_function											owl:Class	
GO:0047362	biolink:NamedThing	thiosulfate-dithiol sulfurtransferase activity	Catalysis of the reaction: dithioerythritol + thiosulfate = hydrogen sulfide + dithioerythritol disulfide + sulfite.	tmpzr1t_l9r_go_relaxed.owl	thiosulphate-dithiol sulphurtransferase activity|thiosulfate:dithioerythritol sulfurtransferase activity|TSR|thiosulfate reductase activity				RHEA:15121|EC:2.8.1.5|MetaCyc:2.8.1.5-RXN									molecular_function											owl:Class	
GO:0035629	biolink:NamedThing	N-terminal protein amino acid N-linked glycosylation	Addition of a carbohydrate or carbohydrate derivative unit via a nitrogen (N) atom of the N-terminal amino acid of a protein.	tmpzr1t_l9r_go_relaxed.owl						Note that the only known alpha amino glycosylation is on an asparagine; see UniProtKB:P58522. However, this feature is not differentiated from normal N-glycosylation of asparagine.		bf	2010-12-17T10:45:48Z					biological_process											owl:Class	
GO:0097601	biolink:NamedThing	retina blood vessel maintenance	A retina homeostatic process preventing the degeneration of a retina blood vessel.	tmpzr1t_l9r_go_relaxed.owl	maintenance of retina blood vessel|maintenance of choriocapillaris|maintenance of retinal blood vessel							pr	2014-05-11T18:42:24Z					biological_process											owl:Class	
GO:0150059	biolink:NamedThing	amylin receptor 1 signaling pathway	A series of molecular signals initiated by an extracellular amylin, or another ligand, combining with an amylin receptor 1 (AMY1), a G protein-coupled receptor complex, on the surface of the target cell. Other ligands that have been shown to initiate the AMY1 signaling pathway include the calcitonin related peptide (CGRP) and adrenomedullin (AM/ADM).	tmpzr1t_l9r_go_relaxed.owl	AMY1 signaling pathway							bc	2018-06-21T10:58:02Z					biological_process											owl:Class	
GO:0036467	biolink:NamedThing	5-hydroxy-L-tryptophan decarboxylase activity	Catalysis of the reaction: 5-hydroxy-L-tryptophan + H+ = CO2 + serotonin.	tmpzr1t_l9r_go_relaxed.owl	5-hydroxytryptophan decarboxylase activity				RHEA:18533			bf	2014-07-21T09:22:24Z					molecular_function											owl:Class	
GO:0034863	biolink:NamedThing	2,4,4-trimethyl-1-pentanol dehydrogenase activity	Catalysis of the reaction: 2,4,4-trimethyl-1-pentanol = 2,4,4-trimethylpentanal + 2 H+ + 2 e-.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r1270									molecular_function											owl:Class	
GO:0045519	biolink:NamedThing	interleukin-23 receptor binding	Binding to an interleukin-23 receptor.	tmpzr1t_l9r_go_relaxed.owl	interleukin-23 receptor ligand|IL-23													molecular_function											owl:Class	
GO:0102504	biolink:NamedThing	luteolinidin 5-O-glucosyltransferase activity	Catalysis of the reaction: luteolinidin + UDP-alpha-D-glucose <=> luteolinidin 5-O-glucoside + UDP + 2 H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-14424									molecular_function											owl:Class	
GO:0021810	biolink:NamedThing	neurotransmitter signaling initiating cell movement, involved in cerebral cortex radial glia guided migration	Signaling by neurotransmitters and their receptors that results in the initiation of movement of cells as a component of the process of glial-mediated radial migration.	tmpzr1t_l9r_go_relaxed.owl	neurotransmitter signalling initiating cell movement, involved in cerebral cortex glial-mediated radial migration													biological_process											owl:Class	
GO:0097417	biolink:NamedThing	nematosome	Cytoplasmic, ball-like inclusion resembling a nucleolus and consisting of a convoluted network of electron-opaque strands embedded in a less dense matrix. It measures approximately 0.9 microns and lacks a limiting membrane. Its strands (diameter = 400-600 A) appear to be made of an entanglement of tightly packed filaments and particles approximately 25-50 A thick. Cytochemical studies suggest the presence of nonhistone proteins and some RNA. Usually only one such structure is present in a cell, and it appears to occur in most ganglion cells. Although they can be seen anywhere in the cell body, nematosomes are typically located in the perinuclear cytoplasm, where they are often associated with smooth-surfaced and coated vesicles.	tmpzr1t_l9r_go_relaxed.owl					NIF_Subcellular:sao138430598			pr	2012-11-06T16:47:56Z					cellular_component											owl:Class	
GO:0070332	biolink:NamedThing	CD20-Lck-Lyn-Fyn complex	A protein complex that contains the cell-surface protein CD20 and the Src family tyrosine kinases Lck, Lyn and Fyn.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0047073	biolink:NamedThing	2,4'-dihydroxyacetophenone dioxygenase activity	Catalysis of the reaction: 2,4'-dihydroxyacetophenone + O(2) = 4-hydroxybenzoate + formate + 2 H(+).	tmpzr1t_l9r_go_relaxed.owl	(4-hydroxybenzoyl)methanol oxygenase activity|2,4'-dihydroxyacetophenone oxidoreductase (C-C-bond-cleaving)				UM-BBD_reactionID:r1410|MetaCyc:1.13.11.41-RXN|KEGG_REACTION:R01305|EC:1.13.11.41|RHEA:24416									molecular_function											owl:Class	
GO:0000171	biolink:NamedThing	ribonuclease MRP activity	Catalysis of the site-specific cleavage of RNA by a catalytic RNA-mediated mechanism; substrates include the A3 site in the ITS1 of pre-rRNA.	tmpzr1t_l9r_go_relaxed.owl	RNase MRP	https://github.com/geneontology/go-ontology/issues/22261			Wikipedia:RNase_MRP									molecular_function											owl:Class	
GO:0050821	biolink:NamedThing	protein stabilization	Any process involved in maintaining the structure and integrity of a protein and preventing it from degradation or aggregation.	tmpzr1t_l9r_go_relaxed.owl	protein sequestering|positive regulation of protein stability|protein stabilisation|protein stabilization activity|lysosomal protein stabilization													biological_process											owl:Class	
GO:0016611	biolink:NamedThing	iron-iron nitrogenase complex	An enzyme complex containing an iron-iron cluster found in species such as the photosynthetic bacterium Rhodobacter capsulatus. It is composed of two main subunits, dinitrogenase and nitrogenase reductase. Dinitrogenase, the iron-iron containing subunit, has an alpha1-beta2 or alpha2-beta2 structure, and the nitrogenase reductase subunit is a homodimer. Functions in the catalysis of the formation of oxidized ferredoxin and ammonia from reduced ferredoxin and nitrogen.	tmpzr1t_l9r_go_relaxed.owl						Note that it is not established whether the nitrogenase exists in vivo in a specific particle or whether the nitrogenase proteins are bound nonspecifically to the membranes of some cells.								cellular_component											owl:Class	
GO:0099073	biolink:NamedThing	mitochondrion-derived vesicle	A vesicle derived via budding from a mitochondrion.  These vesicles often contain inner membrane and, much more rarely, cristae.	tmpzr1t_l9r_go_relaxed.owl	MDV													cellular_component											owl:Class	
GO:0070045	biolink:NamedThing	synaptobrevin 2-SNAP-25-syntaxin-2 complex	A SNARE complex that contains synaptobrevin 2 (VAMP2), SNAP-25, and syntaxin 2 (or orthologs thereof).	tmpzr1t_l9r_go_relaxed.owl	Stx2-Snap25-Vamp2 complex|SNARE complex (Stx2, Snap25, Vamp2)													cellular_component											owl:Class	
GO:0047275	biolink:NamedThing	glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity	Catalysis of the reaction: N-acetyl-D-glucosaminyl-(1,3)-D-galactosyl-(1,4)-D-glucosylceramide + UDP-galactose = D-galactosyl-N-acetyl-D-glucosaminyl-(1,3)-D-galactosyl-(1,4)-D-glucosylceramide + UDP.	tmpzr1t_l9r_go_relaxed.owl	UDP-galactose:N-acetyl-D-glucosaminyl-1,3-D-galactosyl-1,4-D-glucosylceramide beta-D-galactosyltransferase activity|paragloboside synthase activity|uridine diphosphogalactose-acetyl-glucosaminylgalactosylglucosylceramide galactosyltransferase activity|GalT-4|UDPgalactose:N-acetyl-D-glucosaminyl-1,3-D-galactosyl-1,4-D-glucosylceramide beta-D-galactosyltransferase activity				MetaCyc:2.4.1.86-RXN|EC:2.4.1.86|RHEA:16045									molecular_function											owl:Class	
GO:0047586	biolink:NamedThing	5'-acylphosphoadenosine hydrolase activity	Catalysis of the reaction: 5'-acylphosphoadenosine + H2O = AMP + a carboxylate.	tmpzr1t_l9r_go_relaxed.owl	5'-acylphosphoadenosine acylhydrolase activity|5-phosphoadenosine hydrolase activity				EC:3.6.1.20|RHEA:16837|MetaCyc:5-ACYLPHOSPHOADENOSINE-HYDROLASE-RXN									molecular_function											owl:Class	
GO:0072274	biolink:NamedThing	metanephric glomerular basement membrane development	The process whose specific outcome is the progression of the metanephric glomerular basement membrane over time, from its formation to the mature structure. The metanephric glomerular basement membrane is the basal laminal portion of the metanephric glomerulus which performs the actual filtration.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-04-01T02:43:51Z					biological_process											owl:Class	
GO:0102234	biolink:NamedThing	but-1-en-3-one reductase activity	Catalysis of the reaction: buten-2-one + NADPH + H+ <=> butan-2-one + NADP.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-12293									molecular_function											owl:Class	
GO:0043919	biolink:NamedThing	agmatine aminopropyltransferase activity	Catalysis of the reaction: agmatine + S-adenosylmethioninamine = N1-aminopropylagmatine + 5'-methylthioadenosine.	tmpzr1t_l9r_go_relaxed.owl	agmatine aminopropyl transferase activity				EC:2.5.1.104									molecular_function											owl:Class	
GO:0018656	biolink:NamedThing	phenanthrene 3,4-monooxygenase activity	Catalysis of the reaction: phenanthrene + O2 + NADH + H+ = H2O + NAD+ + phenanthrene-3,4-oxide.	tmpzr1t_l9r_go_relaxed.owl					EC:1.14.13.-|UM-BBD_reactionID:r0508									molecular_function											owl:Class	
GO:0102195	biolink:NamedThing	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--D-lysine ligase activity	Catalysis of the reaction: UDP-N-acetylmuramoyl-L-alanyl-D-glutamate + D-lysinium(1+) + ATP <=> UDP-N-acetylmuramoyl-L-alanyl-gamma-D-glutamyl-D-lysine + ADP + hydrogenphosphate + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-12042|RHEA:25273|EC:6.3.2.37									molecular_function											owl:Class	
GO:0010158	biolink:NamedThing	abaxial cell fate specification	The process in which a cell becomes capable of differentiating autonomously into an abaxial cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0061770	biolink:NamedThing	translation elongation factor binding	Binding to a translation elongation factor, any polypeptide factor involved in the peptide elongation in ribosome-mediated translation.	tmpzr1t_l9r_go_relaxed.owl								dph	2016-07-09T09:31:11Z					molecular_function											owl:Class	
GO:0043274	biolink:NamedThing	phospholipase binding	Binding to a phospholipase.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0140080	biolink:NamedThing	class III/IV DNA-(apurinic or apyrimidinic site) endonuclease activity	Catalysis of the cleavage of an AP site 3' and 5' of the baseless site, generating a 3'-phosphate and a 5'-OH.	tmpzr1t_l9r_go_relaxed.owl	endonuclease IV|endonuclease III	https://github.com/geneontology/go-ontology/issues/22262			Wikipedia:AP_endonuclease	Note that this term is does not have parentage in the 'nuclease activity' branch of the ontology because both GO and the Enzyme Commission define nuclease activity as a type of hydrolysis. Class II AP endonuclease is a nuclease, but not Class I, III and IV.		pg	2017-07-24T11:48:18Z					molecular_function											owl:Class	
GO:0018400	biolink:NamedThing	peptidyl-proline hydroxylation to 3-hydroxy-L-proline	The modification of peptidyl-proline to form 3-hydroxy-L-proline; catalyzed by procollagen-proline 3-dioxygenase.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0029	See also the molecular function term 'procollagen-proline 3-dioxygenase activity ; GO:0019797'.								biological_process											owl:Class	
GO:0046593	biolink:NamedThing	mandelonitrile lyase activity	Catalysis of the reaction: mandelonitrile = cyanide + benzaldehyde.	tmpzr1t_l9r_go_relaxed.owl	mandelonitrile benzaldehyde-lyase (cyanide-forming)|hydroxynitrile lyase activity|D-alpha-hydroxynitrile lyase activity|(R)-oxynitrilase activity|mandelonitrile benzaldehyde-lyase activity|D-oxynitrilase activity				RHEA:18313|EC:4.1.2.10|MetaCyc:MANDELONITRILE-LYASE-RXN									molecular_function											owl:Class	
GO:0097548	biolink:NamedThing	seed abscission	The controlled shedding of a seed.	tmpzr1t_l9r_go_relaxed.owl								pr	2014-01-22T07:57:41Z					biological_process											owl:Class	
GO:0071360	biolink:NamedThing	cellular response to exogenous dsRNA	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an exogenous double-stranded RNA stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to viral dsRNA|cellular response to exogenous double-stranded RNA							mah	2009-12-11T03:02:00Z					biological_process											owl:Class	
GO:0097181	biolink:NamedThing	protein C inhibitor-coagulation factor V complex	A heterodimeric protein complex that contains protein C inhibitor (SERPINA5) and coagulation factor V (F5); formation of the complex inhibits the serine protease activity of coagulation factor V.	tmpzr1t_l9r_go_relaxed.owl	PCI-coagulation factor V complex|SERPINA5-coagulation factor V complex|plasma serine protease inhibitor-coagulation factor V complex|serpin A5-coagulation factor V complex|protein C inhibitor-F5 complex							pr	2011-10-16T08:57:03Z					cellular_component											owl:Class	
GO:0097344	biolink:NamedThing	Rix1 complex	A protein complex that comprises Rix1p, Ipi1p and Ipi3p, and is required for processing of ITS2 sequences from 35S pre-rRNA. The Rix1 complex has been identified in budding yeast and fission yeast, and members of this complex are conserved in higher eukaryotes.	tmpzr1t_l9r_go_relaxed.owl	IPI complex							pr	2012-06-18T01:38:49Z					cellular_component											owl:Class	
GO:0097112	biolink:NamedThing	gamma-aminobutyric acid receptor clustering	The receptor clustering process in which gamma-aminobutyric acid (GABA) receptors are localized to distinct domains in the cell membrane.	tmpzr1t_l9r_go_relaxed.owl	GABA receptor clustering							pr	2011-07-31T05:21:08Z					biological_process											owl:Class	
GO:0047644	biolink:NamedThing	alizarin 2-beta-glucosyltransferase activity	Catalysis of the reaction: alizarin + UDP-D-glucose = 1-hydroxy-2-(beta-D-glucosyloxy)-9,10-anthraquinone + H(+) + UDP.	tmpzr1t_l9r_go_relaxed.owl	alizarin 2-b-glucosyltransferase activity|UDPglucose:1,2-dihydroxy-9,10-anthraquinone 2-O-beta-D-glucosyl-transferase activity|UDP-glucose:1,2-dihydroxy-9,10-anthraquinone 2-O-beta-D-glucosyltransferase activity|uridine diphosphoglucose-alizarin glucosyltransferase activity				EC:2.4.1.103|RHEA:20677|MetaCyc:ALIZARIN-2-BETA-GLUCOSYLTRANSFERASE-RXN|KEGG_REACTION:R03573									molecular_function											owl:Class	
GO:0010196	biolink:NamedThing	nonphotochemical quenching	The process by which excess light energy absorbed by chlorophyll and not used to drive photosynthesis is emitted as heat. This process helps maintain the balance between dissipation and utilization of light energy to minimize generation of oxidizing molecules, thereby protecting the plant against photo-oxidative damage.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0008790	biolink:NamedThing	arabinose isomerase activity	Catalysis of the reaction: D-arabinose = D-ribulose.	tmpzr1t_l9r_go_relaxed.owl	D-arabinose(L-fucose) isomerase activity|D-arabinose isomerase activity|D-arabinose aldose-ketose-isomerase activity|D-arabinose ketol-isomerase activity				EC:5.3.1.3|RHEA:13849|MetaCyc:DARABISOM-RXN									molecular_function											owl:Class	
GO:0047019	biolink:NamedThing	indole-3-acetaldehyde reductase (NADPH) activity	Catalysis of the reaction: indole-3-ethanol + NADP(+) = (indol-3-yl)acetaldehyde + H(+) + NADPH.	tmpzr1t_l9r_go_relaxed.owl	(indol-3-yl)ethanol:NADP+ oxidoreductase activity|indoleacetaldehyde (reduced nicotinamide adenine dinucleotide phosphate) reductase activity|indole-3-ethanol:NADP+ oxidoreductase activity				KEGG_REACTION:R02680|EC:1.1.1.191|MetaCyc:1.1.1.191-RXN|RHEA:17037									molecular_function											owl:Class	
GO:0071189	biolink:NamedThing	protocadherin-alpha-v7-protocadherin-gamma-a3 complex	A protein complex that contains the cell adhesion molecules protocadherin-alpha-v7 and protocadherin-gamma-a3, and is involved in the regulation of protein localization to the plasma membrane.	tmpzr1t_l9r_go_relaxed.owl	Pcdha7-Pcdhga3 complex							mah	2009-11-23T04:24:28Z					cellular_component											owl:Class	
GO:0050299	biolink:NamedThing	streptomycin 3''-kinase activity	Catalysis of the reaction: ATP + streptomycin = ADP + 2 H(+) + streptomycin 3''-phosphate.	tmpzr1t_l9r_go_relaxed.owl	ATP:streptomycin 3''-phosphotransferase activity|streptomycin 3''-kinase (phosphorylating)|streptomycin 3''-phosphotransferase activity				KEGG_REACTION:R02227|MetaCyc:STREPTOMYCIN-3-KINASE-RXN|RHEA:18377|EC:2.7.1.87									molecular_function											owl:Class	
GO:0072449	biolink:NamedThing	response to G1 cell size control checkpoint signaling	A process that occurs in response to signals generated as a result of mitotic cell cycle G1/S transition size control checkpoint signaling.	tmpzr1t_l9r_go_relaxed.owl	response to signal involved in mitotic cell cycle G1/S transition size control checkpoint|mitotic cell cycle G1/S transition size control checkpoint effector process							mah	2010-12-09T10:56:39Z					biological_process											owl:Class	
GO:0060772	biolink:NamedThing	leaf phyllotactic patterning	The radial pattern formation process that results in the formation of leaf primordia around the center of a shoot apical meristem.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-07-25T06:27:15Z					biological_process											owl:Class	
GO:0071127	biolink:NamedThing	alpha9-beta1 integrin-osteopontin complex	A protein complex that consists of an alpha9-beta1 integrin complex bound to osteopontin.	tmpzr1t_l9r_go_relaxed.owl	ITGA9-ITGB1-SPP1 complex							mah	2009-11-13T02:24:09Z					cellular_component											owl:Class	
GO:0106332	biolink:NamedThing	ds/ssDNA junction-specific dsDNA endonuclease activity	Catalysis of the endonucleolytic cleavage of double-stranded DNA near a double-strand/single-strand DNA junction.	tmpzr1t_l9r_go_relaxed.owl								hjd	2020-10-08T18:09:57Z					molecular_function											owl:Class	
GO:0018399	biolink:NamedThing	peptidyl-phenylalanine bromination to L-4'-bromophenylalanine	The bromination of peptidyl-phenylalanine to form L-4'-bromophenylalanine.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0176									biological_process											owl:Class	
GO:0044654	biolink:NamedThing	starch alpha-glucosidase activity	Catalysis of the reaction: starch + H2O = alpha-D-glucose.	tmpzr1t_l9r_go_relaxed.owl					EC:3.2.1.-			jl	2012-07-23T02:08:10Z					molecular_function											owl:Class	
GO:0031854	biolink:NamedThing	orexigenic neuropeptide QRFP receptor binding	Binding to an orexigenic neuropeptide QRFP receptor.	tmpzr1t_l9r_go_relaxed.owl	orexigenic neuropeptide QRFP receptor ligand													molecular_function											owl:Class	
GO:0021741	biolink:NamedThing	spinal trigeminal nucleus development	The process whose specific outcome is the progression of the spinal trigeminal nucleus over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0102114	biolink:NamedThing	caprate dehydroxylase activity	Catalysis of the reaction: decanoate + NADPH + O2 + H+ <=> 10-hydroxycaprate + NADP + H2O.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-11325									molecular_function											owl:Class	
GO:0080102	biolink:NamedThing	3-methylthiopropyl glucosinolate S-oxygenase activity	Catalysis of the reaction: 3-methylthiopropyl-glucosinolate = 3-methylsulfinylpropyl-glucosinolate.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-2221			dhl	2009-04-23T04:26:41Z					molecular_function											owl:Class	
GO:0050012	biolink:NamedThing	juglone 3-hydroxylase activity	Catalysis of the reaction: 2 juglone + O2 = 2 3,5-dihydroxy-1,4-naphthoquinone + 2 H+.	tmpzr1t_l9r_go_relaxed.owl	juglone hydroxylase activity|naphthoquinone hydroxylase activity|juglone 3-monooxygenase activity|5-hydroxy-1,4-naphthoquinone,hydrogen-donor:oxygen oxidoreductase (3-hydroxylating)	https://github.com/geneontology/go-ontology/issues/21412			RHEA:18745|EC:1.17.3.4|MetaCyc:JUGLONE-3-MONOOXYGENASE-RXN|KEGG_REACTION:R04327	Formerly EC:1.14.99.27.								molecular_function											owl:Class	
GO:0044680	biolink:NamedThing	methylthiol:coenzyme M methyltransferase complex	A protein complex of two polypeptides which catalyzes the transfer of methyl group from methylthiol to coenzyme M during methanogenesis.	tmpzr1t_l9r_go_relaxed.owl	methylthiol:coenzyme M methyl transferase complex|methylthiol coenzyme M methyl transferase complex|methylthiol:CoM methyltransferase complex							jl	2012-08-09T11:08:22Z					cellular_component											owl:Class	
GO:0018805	biolink:NamedThing	benzylsuccinate synthase activity	Catalysis of the reaction: fumarate + toluene = 2-benzylsuccinate.	tmpzr1t_l9r_go_relaxed.owl	benzylsuccinate fumarate-lyase activity|benzylsuccinate fumarate-lyase (toluene-forming)				RHEA:10416|MetaCyc:RXN-863|UM-BBD_enzymeID:e0259|EC:4.1.99.11|KEGG_REACTION:R05598									molecular_function											owl:Class	
GO:0047637	biolink:NamedThing	alanylphosphatidylglycerol synthase activity	Catalysis of the reaction: L-alanyl-tRNA + phosphatidylglycerol = tRNA + 3-O-L-alanyl-1-O-phosphatidylglycerol.	tmpzr1t_l9r_go_relaxed.owl	O-alanylphosphatidylglycerol synthase activity|alanyl phosphatidylglycerol synthetase activity|L-alanyl-tRNA:phosphatidylglycerol alanyltransferase activity				RHEA:20489|EC:2.3.2.11|MetaCyc:ALANYLPHOSPHATIDYLGLYCEROL-SYNTHASE-RXN									molecular_function											owl:Class	
GO:0010098	biolink:NamedThing	suspensor development	The process whose specific outcome is the progression of the suspensor over time, from its formation to the mature structure. The suspensor is the extension at the base of the embryo that anchors the embryo in the embryo sac and pushes it into the endosperm.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0030792	biolink:NamedThing	methylarsonite methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + methylarsonite = S-adenosyl-L-homocysteine + dimethylarsinate.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:2.1.1.138-RXN|EC:2.1.1.-	Note that EC:2.1.1.138 was deleted from EC as the reaction is performed by arsenite methyltransferase (EC:2.1.1.137).								molecular_function											owl:Class	
GO:0090550	biolink:NamedThing	response to molybdenum starvation	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of molybdenum.	tmpzr1t_l9r_go_relaxed.owl								tb	2013-04-22T13:57:16Z					biological_process											owl:Class	
GO:0102413	biolink:NamedThing	6-O-methyl-deacetylisoipecoside beta-glucosidase activity	Catalysis of the reaction: 6-O-methyl-N-deacetylisoipecoside + H2O <=> 6-O-methyl-N-deacetylisoipecoside aglycon + beta-D-glucose.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-13791									molecular_function											owl:Class	
GO:0018645	biolink:NamedThing	alkene monooxygenase activity	Catalysis of the reaction: propene + NADH + H+ + O2 = 1,2-epoxypropane + NAD+ + H2O.	tmpzr1t_l9r_go_relaxed.owl	alkene,NADH:oxygen oxidoreductase activity|alkene epoxygenase activity				MetaCyc:1.14.13.69-RXN|UM-BBD_enzymeID:e0039|RHEA:11792|EC:1.14.13.69									molecular_function											owl:Class	
GO:0036237	biolink:NamedThing	acyl-glucuronidase activity	Catalysis of the reaction: an acyl-glucuronoside + H2O = an alcohol + D-glucuronate.	tmpzr1t_l9r_go_relaxed.owl	acyl-glucuronide deglucuronidation activity							bf	2012-05-18T04:32:25Z					molecular_function											owl:Class	
GO:0019598	biolink:NamedThing	(R)-mandelate catabolic process to catechol	The chemical reactions and pathways resulting in the breakdown of (R)-mandelate into other compounds, including catechol.	tmpzr1t_l9r_go_relaxed.owl	(R)-mandelate degradation to catechol|(R)-mandelate breakdown to catechol													biological_process											owl:Class	
GO:0097169	biolink:NamedThing	AIM2 inflammasome complex	An inflammasome complex that consists of AIM2, ASC, and caspase-1. AIM2 is a member of the HN-200 protein family that appears to be the sensor of cytosolic double-stranded DNA.	tmpzr1t_l9r_go_relaxed.owl								pr	2011-10-03T07:36:21Z					cellular_component											owl:Class	
GO:0004309	biolink:NamedThing	exopolyphosphatase activity	Catalysis of the reaction: polyphosphate(n) + H2O = polyphosphate(n-1) + phosphate.	tmpzr1t_l9r_go_relaxed.owl	acid phosphoanhydride phosphohydrolase activity|Gra-Pase activity|polyphosphate phosphohydrolase activity|exopolypase activity|metaphosphatase activity				RHEA:21528|EC:3.6.1.11|MetaCyc:EXOPOLYPHOSPHATASE-RXN									molecular_function											owl:Class	
GO:0102465	biolink:NamedThing	zeaxanthin 2,2'-beta-hydroxylase activity	Catalysis of the reaction: zeaxanthin + 2 NADH + 2 H+ + 2 O2 <=> nostoxanthin + 2 NAD + 2 H2O.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-14018									molecular_function											owl:Class	
GO:0033845	biolink:NamedThing	hydroxymethylfurfural reductase (NADPH) activity	Catalysis of the reaction: 5-hydroxymethylfurfural + NADPH + H+ = 2,5-bis-hydroxymethylfuran + NADP+.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0018527	biolink:NamedThing	cyclohexylamine oxidase activity	Catalysis of the reaction: cyclohexylamine + O2 + H2O = cyclohexanone + NH3 + hydrogen peroxide.	tmpzr1t_l9r_go_relaxed.owl	cyclohexylamine:oxygen oxidoreductase (deaminating)				UM-BBD_reactionID:r0754|RHEA:18433|EC:1.4.3.12|MetaCyc:CYCLOHEXYLAMINE-OXIDASE-RXN									molecular_function											owl:Class	
GO:1990082	biolink:NamedThing	DnaA-L2 complex	A protein complex that inhibits unwinding of DNA at the origin of replication and assembly of the pre-primosome. In E. coli, this complex is composed of DnaA and of the ribosomal protein L2.	tmpzr1t_l9r_go_relaxed.owl								bhm	2013-04-30T11:46:41Z					cellular_component											owl:Class	
GO:0050644	biolink:NamedThing	cis-p-coumarate glucosyltransferase activity	Catalysis of the reaction: cis-4-coumarate + UDP-D-glucose = 4'-O-beta-D-glucosyl-cis-4-coumarate + H(+) + UDP.	tmpzr1t_l9r_go_relaxed.owl	UDP-glucose:cis-p-coumarate beta-D-glucosyltransferase activity				RHEA:13129|EC:2.4.1.209|KEGG_REACTION:R05324|MetaCyc:2.4.1.209-RXN									molecular_function											owl:Class	
GO:0097080	biolink:NamedThing	plasma membrane selenite transport	The directed movement of inorganic selenite (HSeO3-1 at physiological pH) across a plasma membrane.	tmpzr1t_l9r_go_relaxed.owl	plasma membrane hydrogenselenite transport							pr	2011-06-17T10:03:55Z					biological_process											owl:Class	
GO:0036247	biolink:NamedThing	phytochelatin 3 import into vacuole	The directed movement of phytochelatin 3 (PC3) into the vacuole. Phytochelatin 3 is a glutathione-related peptide composed of (gamma-Glu-Cys)n-Gly where n=3, and where the Glu and Cys residues are linked through a gamma-carboxylamide bond.	tmpzr1t_l9r_go_relaxed.owl	PC3 import into vacuole							bf	2012-05-31T11:11:03Z					biological_process											owl:Class	
GO:0052785	biolink:NamedThing	cellulose catabolism by endo-processive cellulases	The breakdown into simpler components of cellulose. Catabolism is initiated by endohydrolytic attacks on the cellulose chain, and the resulting pieces are further degraded by cellulase enzymes to produce smaller and smaller fragments.	tmpzr1t_l9r_go_relaxed.owl	endo-processive cellulase activity							ai	2011-10-04T09:31:16Z					biological_process											owl:Class	
GO:0009600	biolink:NamedThing	detection of nematode	The series of events in which a stimulus from a nematode is received and converted into a molecular signal.	tmpzr1t_l9r_go_relaxed.owl	perception of nematode													biological_process											owl:Class	
GO:0103025	biolink:NamedThing	alpha-amylase activity (releasing maltohexaose)	Catalysis of the reaction: n H2O + a 1,4-alpha-D-glucan = alpha-maltohexaose + a 1,4-alpha-D-glucan.	tmpzr1t_l9r_go_relaxed.owl					EC:3.2.1.1|MetaCyc:RXN0-5181									molecular_function											owl:Class	
GO:0042202	biolink:NamedThing	N-cyclopropylmelamine catabolic process	The chemical reactions and pathways resulting in the breakdown of N-cyclopropylmelamine, a triazine compound commonly used as an insecticide.	tmpzr1t_l9r_go_relaxed.owl	N-cyclopropylmelamine breakdown|cyromazine catabolic process|N-cyclopropylmelamine degradation|N-cyclopropylmelamine catabolism|cyromazine catabolism				UM-BBD_pathwayID:cpm									biological_process											owl:Class	
GO:0050143	biolink:NamedThing	nocardicin-A epimerase activity	Catalysis of the reaction: isonocardicin A = nocardicin A.	tmpzr1t_l9r_go_relaxed.owl	isonocardicin A epimerase activity				EC:5.1.1.14|RHEA:22792|MetaCyc:NOCARDICIN-A-EPIMERASE-RXN|KEGG_REACTION:R03073									molecular_function											owl:Class	
GO:1904157	biolink:NamedThing	DN4 thymocyte differentiation	The process in which a relatively unspecialized cell acquires the specialized features of a DN4 thymocyte. A DN4 thymocyte is a CD4-,CD8- thymocyte that is also CD44-,CD25-.	tmpzr1t_l9r_go_relaxed.owl								dph	2015-04-15T12:53:07Z					biological_process											owl:Class	
GO:0070038	biolink:NamedThing	rRNA (pseudouridine-N3-)-methyltransferase activity	Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing N3-methylpseudouridine.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0004333	biolink:NamedThing	fumarate hydratase activity	Catalysis of the reaction: (S)-malate = fumarate + H(2)O.	tmpzr1t_l9r_go_relaxed.owl	(S)-malate hydro-lyase (fumarate-forming)|L-malate hydro-lyase activity|fumarase activity|(S)-malate hydro-lyase activity				MetaCyc:FUMHYDR-RXN|EC:4.2.1.2|KEGG_REACTION:R01082|RHEA:12460|Reactome:R-HSA-451033|Reactome:R-HSA-70982									molecular_function											owl:Class	
GO:0046564	biolink:NamedThing	oxalate decarboxylase activity	Catalysis of the reaction: H(+) + oxalate = CO(2) + formate.	tmpzr1t_l9r_go_relaxed.owl	oxalate carboxy-lyase activity|oxalate carboxy-lyase (formate-forming)				MetaCyc:OXALATE-DECARBOXYLASE-RXN|KEGG_REACTION:R00522|RHEA:16509|EC:4.1.1.2									molecular_function											owl:Class	
GO:0046353	biolink:NamedThing	aminoglycoside 3-N-acetyltransferase activity	Catalysis of the reaction: acetyl-CoA + aminoglycoside = CoA + 3-N-acetylaminoglycoside. This is acetylation of the 3-amino group of the central deoxystreptamine ring.	tmpzr1t_l9r_go_relaxed.owl	gentamicin-(3)-N-acetyltransferase activity|gentamycin acetyltransferase I|gentamycin 3'-N-acetyltransferase activity|3'-aminoglycoside acetyltransferase activity|gentamicin acetyltransferase I activity|gentamicin 3'-N-acetyltransferase activity|acetyl-CoA:gentamicin-C N3'-acetyltransferase activity|acetyl-CoA:2-deoxystreptamine-antibiotic N3'-acetyltransferase activity|3-N-aminoglycoside acetyltransferase activity|aminoglycoside acetyltransferase AAC(3)-I activity|aminoglycoside acetyltransferase AAC(3)-1				MetaCyc:GENTAMICIN-3-N-ACETYLTRANSFERASE-RXN|EC:2.3.1.81|MetaCyc:AMINOGLYCOSIDE-N3-ACETYLTRANSFERASE-RXN|EC:2.3.1.60							GO:0016991		molecular_function											owl:Class	
GO:0043726	biolink:NamedThing	5-amino-6-(5-phosphoribitylamino)uracil phosphatase activity	Catalysis of the reaction: 5-amino-6-(5-phosphoribitylamino)-2,4(1H,3H)-pyrimidinedione + H2O = 5-amino-6-ribitylamino-2,4(1H,3H)-pyrimidinedione + orthophosphate.	tmpzr1t_l9r_go_relaxed.owl	pyrimidine phosphatase activity				RHEA:25197|MetaCyc:RIBOPHOSPHAT-RXN							GO:0019173		molecular_function											owl:Class	
GO:0010151	biolink:NamedThing	chloroplast elongation	Expansion of the chloroplast that usually precedes division.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0045352	biolink:NamedThing	interleukin-1 type I receptor antagonist activity	Blocks the binding of interleukin-1 to interleukin-1 type I receptors.	tmpzr1t_l9r_go_relaxed.owl	IL-1ra type I													molecular_function											owl:Class	
GO:0102464	biolink:NamedThing	zeaxanthin 2-beta-hydroxylase activity	Catalysis of the reaction: zeaxanthin + O2 + NADH + H+ <=> caloxanthin + H2O + NAD.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-14016									molecular_function											owl:Class	
GO:0050561	biolink:NamedThing	glutamate-tRNA(Gln) ligase activity	Catalysis of the reaction: tRNA(Glx) + L-glutamate + ATP = glutamyl-tRNA(Glx) + diphosphate + AMP.	tmpzr1t_l9r_go_relaxed.owl	nondiscriminating glutamyl-tRNA synthetase activity|glutamate-tRNAGln ligase activity|L-glutamate:tRNAGlx ligase (AMP-forming)				EC:6.1.1.24|RHEA:18397|MetaCyc:6.1.1.24-RXN									molecular_function											owl:Class	
GO:0030165	biolink:NamedThing	PDZ domain binding	Binding to a PDZ domain of a protein, a domain found in diverse signaling proteins.	tmpzr1t_l9r_go_relaxed.owl	GLGF-domain binding|DHR-domain binding													molecular_function											owl:Class	
GO:0003935	biolink:NamedThing	GTP cyclohydrolase II activity	Catalysis of the reaction: GTP + 3 H(2)O = 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)-pyrimidine + diphosphate + formate + 3 H(+).	tmpzr1t_l9r_go_relaxed.owl	GTP-8-formylhydrolase activity|guanosine triphosphate cyclohydrolase II|GTP 7,8-8,9-dihydrolase (diphosphate-forming)				RHEA:23704|MetaCyc:GTP-CYCLOHYDRO-II-RXN|EC:3.5.4.25|KEGG_REACTION:R00425									molecular_function											owl:Class	
GO:0033514	biolink:NamedThing	L-lysine catabolic process to acetyl-CoA via L-pipecolate	The chemical reactions and pathways resulting in the breakdown of L-lysine into other compounds, including acetyl-CoA, via the intermediate L-pipecolate.	tmpzr1t_l9r_go_relaxed.owl	L-lysine degradation to acetyl-CoA via L-pipecolate|L-lysine breakdown to acetyl-CoA via L-pipecolate				MetaCyc:PWY-5283									biological_process											owl:Class	
GO:0047197	biolink:NamedThing	triglyceride-sterol O-acyltransferase activity	Catalysis of the reaction: a 3-beta-hydroxysterol + triacylglycerol = a 3-beta-hydroxysterol ester + 1,2-diacylglycerol.	tmpzr1t_l9r_go_relaxed.owl	triacylglycerol:sterol acyltransferase activity|triacylglycerol-sterol O-acyltransferase activity|triacylglycerol:3beta-hydroxysterol O-acyltransferase activity				EC:2.3.1.77|MetaCyc:2.3.1.77-RXN|RHEA:16897									molecular_function											owl:Class	
GO:0099076	biolink:NamedThing	mitochondrion to peroxisome transport	Transport from the mitochondrion to the peroxisome, mediated by mitochondrion-derived vesicles.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0061420	biolink:NamedThing	regulation of transcription from RNA polymerase II promoter in response to biotin starvation	Modulation of the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of deprivation of biotin.	tmpzr1t_l9r_go_relaxed.owl								dph	2012-01-25T09:55:39Z					biological_process											owl:Class	
GO:0043849	biolink:NamedThing	Ras palmitoyltransferase activity	Catalysis of the reaction: palmitoyl-CoA + protein-cysteine = S-palmitoyl protein + CoA, specific for Ras proteins.	tmpzr1t_l9r_go_relaxed.owl	Ras protein acyltransferase activity|DHHC cysteine-rich domain-containing protein ERF2|palmitoyltransferase ERF2|ERF2													molecular_function											owl:Class	
GO:0047405	biolink:NamedThing	pyrimidine-5'-nucleotide nucleosidase activity	Catalysis of the reaction: H2O + a pyrimidine 5'-nucleotide = ribose-5-phosphate + a pyrimidine.	tmpzr1t_l9r_go_relaxed.owl	pyrimidine-5'-nucleotide phosphoribo(deoxyribo)hydrolase activity|pyrimidine nucleotide N-ribosidase activity|Pyr5N activity				RHEA:13425|MetaCyc:3.2.2.10-RXN|EC:3.2.2.10									molecular_function											owl:Class	
GO:0047483	biolink:NamedThing	imidazoleacetate-phosphoribosyldiphosphate ligase activity	Catalysis of the reaction: 5-phospho-alpha-D-ribose 1-diphosphate + ATP + H(2)O + imidazol-4-ylacetate = 1-(5-phosphoribosyl)imidazol-4-ylacetate + ADP + diphosphate + 2 H(+) + phosphate.	tmpzr1t_l9r_go_relaxed.owl	imidazoleacetate:5-phosphoribosyl-diphosphate ligase (ADP- and diphosphate-forming)|5-phosphoribosylimidazoleacetate synthetase activity				EC:6.3.4.8|RHEA:16485|MetaCyc:6.3.4.8-RXN|KEGG_REACTION:R04068									molecular_function											owl:Class	
GO:0033442	biolink:NamedThing	AAC codon-amino acid adaptor activity	A triplet codon-amino acid adaptor activity that recognizes an AAC codon.	tmpzr1t_l9r_go_relaxed.owl	asparagine tRNA					Note that in the standard genetic code, AAC codes for asparagine.								molecular_function											owl:Class	
GO:0008797	biolink:NamedThing	aspartate ammonia-lyase activity	Catalysis of the reaction: L-aspartate = fumarate + NH3.	tmpzr1t_l9r_go_relaxed.owl	L-aspartate ammonia-lyase activity|L-aspartase activity|fumaric aminase activity|aspartase activity|L-aspartate ammonia-lyase (fumarate-forming)				EC:4.3.1.1|MetaCyc:ASPARTASE-RXN|RHEA:16601									molecular_function											owl:Class	
GO:0034738	biolink:NamedThing	lanosterol O-acyltransferase activity	Catalysis of the reaction: acyl-CoA + lanosterol = CoA + lanosterol ester.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0047535	biolink:NamedThing	2-alkyn-1-ol dehydrogenase activity	Catalysis of the reaction: 2-butyne-1,4-diol + NAD(+) = 4-hydroxy-2-butynal + H(+) + NADH.	tmpzr1t_l9r_go_relaxed.owl	2-butyne-1,4-diol:NAD+ 1-oxidoreductase activity				EC:1.1.1.165|MetaCyc:2-ALKYN-1-OL-DEHYDROGENASE-RXN|RHEA:19101|KEGG_REACTION:R03963									molecular_function											owl:Class	
GO:0019246	biolink:NamedThing	L(+)-lactate biosynthetic process from pyruvate	The chemical reactions and pathways resulting in the formation of L(+)-lactate from other compounds, including pyruvate.	tmpzr1t_l9r_go_relaxed.owl	L(+)-lactate synthesis from pyruvate|L(+)-lactate formation from pyruvate|S-lactate biosynthetic process from pyruvate|L(+)-lactate anabolism from pyruvate				MetaCyc:PWY-5481									biological_process											owl:Class	
GO:1990911	biolink:NamedThing	response to psychosocial stress	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of exposure to aversive or demanding psychological and social conditions that tax or exceed the behavioral resources of the organism.	tmpzr1t_l9r_go_relaxed.owl								sl	2015-12-07T20:38:35Z					biological_process											owl:Class	
GO:0061867	biolink:NamedThing	establishment of mitotic spindle asymmetry	The mitotic spindle organization process by which a mitotic spindle becomes asymmetric either in position or structure.	tmpzr1t_l9r_go_relaxed.owl								dph	2017-04-28T12:39:13Z					biological_process											owl:Class	
GO:0035202	biolink:NamedThing	tracheal pit formation in open tracheal system	Formation of the tracheal pits, the first tube-like structures to form in the open tracheal system. Once cells are determined to their tracheal cell fate, the tracheal pits arise by invagination of each ectodermal cluster of tracheal placode cells, between 5 and 7 hours after egg laying. An example of this is found in Drosophila melanogaster.	tmpzr1t_l9r_go_relaxed.owl	tracheal sac formation|tracheal placode invagination													biological_process											owl:Class	
GO:0015921	biolink:NamedThing	lipopolysaccharide export	The directed movement of lipopolysaccharides out of a cell or organelle.	tmpzr1t_l9r_go_relaxed.owl	LPS export													biological_process											owl:Class	
GO:0003975	biolink:NamedThing	UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase activity	Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + dolichyl phosphate = UMP + N-acetyl-D-glucosaminyl-diphosphodolichol.	tmpzr1t_l9r_go_relaxed.owl	N-acetylglucosamine-1-phosphate transferase activity|chitobiosylpyrophosphoryldolichol synthase activity|UDP-acetylglucosamine-dolichol phosphate acetylglucosamine phosphotransferase activity|UDP-GlcNAc:dolichyl-phosphate GlcNAc-1-phosphate transferase activity|UDP-N-acetyl-D-glucosamine:dolichol phosphate N-acetyl-D-glucosamine-1-phosphate transferase activity|GlcNAc-1-P transferase activity|UDP-N-acetyl-D-glucosamine:dolichyl-phosphate N-acetyl-D-glucosaminephosphotransferase activity|dolichol phosphate N-acetylglucosamine-1-phosphotransferase activity|uridine diphosphoacetylglucosamine-dolichyl phosphate acetylglucosamine-1-phosphotransferase activity|UDP-acetylglucosamine-dolichol phosphate acetylglucosamine-1-phosphotransferase activity|UDP-D-N-acetylglucosamine N-acetylglucosamine 1-phosphate transferase activity|UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosamine-1-phosphate transferase activity				RHEA:13289|MetaCyc:2.7.8.15-RXN|Reactome:R-HSA-4549334|Reactome:R-HSA-446191|EC:2.7.8.15									molecular_function											owl:Class	
GO:0009661	biolink:NamedThing	chromoplast organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the chromoplast. A chromoplast is a plastid containing pigments other than chlorophyll, usually yellow and orange carotenoid pigments.	tmpzr1t_l9r_go_relaxed.owl	chromoplast organisation|chromoplast organization and biogenesis													biological_process											owl:Class	
GO:1990014	biolink:NamedThing	orthogonal array	Square array of closely spaced intramembrane particles, 4-6 nm in size, that form supramolecular aggregates found in the plasma membrane of astrocytes, skeletal muscle and epithelial cells. They have been shown to contain aquaporins (water channels).	tmpzr1t_l9r_go_relaxed.owl	orthogonal array of particles|OAP|square array				NIF_Subcellular:sao1747012216			pr	2012-12-13T20:14:15Z					cellular_component											owl:Class	
GO:0102367	biolink:NamedThing	2-alpha-hydroxytaxusin 7-beta-hydroxylase activity	Catalysis of the reaction: 2alpha-hydroxytaxusin + NADPH + O2 + H+ <=> 2alpha, 7beta-dihydroxytaxusin + NADP + H2O.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-13488									molecular_function											owl:Class	
GO:0046876	biolink:NamedThing	3,4-didehydroretinal binding	Binding to 3,4-didehydroretinal, a form of retinal that plays a role in the visual process in freshwater fish and some amphibians analogous to that of all-trans retinal in other vertebrates. 3,4-didehydro-11-cis-retinal combines with an opsin to form cyanopsin (cone) or porphyropsin (rod).	tmpzr1t_l9r_go_relaxed.owl	long-wave-sensitive opsin|blue-sensitive opsin|short-wave-sensitive opsin|violet-sensitive opsin|red-sensitive opsin|green-sensitive opsin|UV-sensitive opsin|opsin													molecular_function											owl:Class	
GO:0031738	biolink:NamedThing	XCR1 chemokine receptor binding	Binding to a XCR1 chemokine receptor.	tmpzr1t_l9r_go_relaxed.owl	XCR1 chemokine receptor ligand|lymphotactin receptor binding													molecular_function											owl:Class	
GO:1904936	biolink:NamedThing	interneuron migration	The orderly movement of an interneuron from one site to another.	tmpzr1t_l9r_go_relaxed.owl	inter neuron migration|inter-neuron migration							ah	2016-02-01T14:04:32Z					biological_process											owl:Class	
GO:1901786	biolink:NamedThing	p-cresol biosynthetic process	The chemical reactions and pathways resulting in the formation of p-cresol.	tmpzr1t_l9r_go_relaxed.owl	p-cresol synthesis|p-cresol biosynthesis|p-cresol formation|p-cresol anabolism							yaf	2013-01-16T11:04:08Z					biological_process											owl:Class	
GO:0043823	biolink:NamedThing	spheroidene monooxygenase activity	Catalysis of the reaction: spheroidene + O2 = spheroidenone + H2O.	tmpzr1t_l9r_go_relaxed.owl					RHEA:33027|MetaCyc:RXN-10670|EC:1.14.15.9									molecular_function											owl:Class	
GO:0102158	biolink:NamedThing	very-long-chain 3-hydroxyacyl-CoA dehydratase activity	Catalysis of the reaction: a very-long-chain (3R)-3-hydroxyacyl-CoA = H2O + a very-long-chain trans-2,3-dehydroacyl-CoA.	tmpzr1t_l9r_go_relaxed.owl					EC:4.2.1.134|MetaCyc:RXN-11750|RHEA:45812									molecular_function											owl:Class	
GO:0140495	biolink:NamedThing	migracytosis	A cell migration-dependent mechanism for releasing cellular contents.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/19760						pg	2020-07-10T15:13:46Z					biological_process											owl:Class	
GO:0033707	biolink:NamedThing	3''-deamino-3''-oxonicotianamine reductase activity	Catalysis of the reaction: 2'-deoxymugineic acid + NAD(P)+ = 3''-deamino-3''-oxonicotianamine + NAD(P)H + H+.	tmpzr1t_l9r_go_relaxed.owl	2'-deoxymugineic acid:NAD(P)+ 3''-oxidoreductase activity				MetaCyc:1.1.1.285-RXN|EC:1.1.1.285									molecular_function											owl:Class	
GO:0102677	biolink:NamedThing	campesterol,NADPH:oxygen oxidoreductase activity	Catalysis of the reaction: H+ + campesterol + O2 + NADPH <=> (22S)-22-hydroxycampesterol + H2O + NADP.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-4225									molecular_function											owl:Class	
GO:0103098	biolink:NamedThing	CYP79F1 tetrahomomethionine monooxygenase activity	Catalysis of the reaction: 2 H+ + tetrahomomethionine + 2 O2 + 2 NADPH <=> 3 H2O + carbon dioxide + 2 NADP + 7-methylthioheptanaldoxime.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXNQT-4311									molecular_function											owl:Class	
GO:0072635	biolink:NamedThing	interleukin-31 production	The appearance of interleukin-31 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	tmpzr1t_l9r_go_relaxed.owl	interleukin-31 secretion|IL-31 production											GO:0072636		biological_process											owl:Class	
GO:0050283	biolink:NamedThing	serine-sulfate ammonia-lyase activity	Catalysis of the reaction: L-serine O-sulfate + H2O = pyruvate + NH3 + sulfate.	tmpzr1t_l9r_go_relaxed.owl	serine-sulphate ammonia-lyase activity|(L-SOS)lyase activity|L-serine-O-sulfate ammonia-lyase (pyruvate-forming)				MetaCyc:SERINE-SULFATE-AMMONIA-LYASE-RXN|EC:4.3.1.10|RHEA:15605									molecular_function											owl:Class	
GO:0046736	biolink:NamedThing	induction of humoral immune response in host by virus	The intentional, virally-encoded stimulation of a host humoral defense response to viral infection.	tmpzr1t_l9r_go_relaxed.owl	active viral induction of humoral immune response in host|active induction of humoral immune response in host by virus													biological_process											owl:Class	
GO:0003885	biolink:NamedThing	D-arabinono-1,4-lactone oxidase activity	Catalysis of the reaction: D-arabinono-1,4-lactone + O(2) = dehydro-D-arabinono-1,4-lactone + H(2)O(2) + H(+).	tmpzr1t_l9r_go_relaxed.owl	D-arabinono-1,4-lactone:oxygen oxidoreductase activity				MetaCyc:1.1.3.37-RXN|RHEA:23756|KEGG_REACTION:R02715|EC:1.1.3.37									molecular_function											owl:Class	
GO:0008820	biolink:NamedThing	cobinamide phosphate guanylyltransferase activity	Catalysis of the reaction: adenosylcobinamide phosphate + GTP + 2 H(+) = adenosylcobinamide-GDP + diphosphate.	tmpzr1t_l9r_go_relaxed.owl	AdoCbi kinase/AdoCbi-phosphate guanylyltransferase|adenosylcobinamide-phosphate guanylyltransferase activity|GTP:adenosylcobinamide-phosphate guanylyltransferase activity|CobU|GTP:cobinamide phosphate guanylyltransferase activity|adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase				EC:2.7.7.62|KEGG_REACTION:R05222|RHEA:22712|MetaCyc:COBINPGUANYLYLTRANS-RXN							GO:0043753		molecular_function											owl:Class	
GO:0033965	biolink:NamedThing	aculeacin-A deacylase activity	Catalysis of the hydrolysis of the amide bond in aculeacin A and related neutral lipopeptide antibiotics, releasing the long-chain fatty acid side-chain.	tmpzr1t_l9r_go_relaxed.owl	aculeacin-A amidohydrolase activity|aculeacin A acylase activity				EC:3.5.1.70|MetaCyc:3.5.1.70-RXN									molecular_function											owl:Class	
GO:0102570	biolink:NamedThing	tyrosine:phenylpyruvate aminotransferase activity	Catalysis of the reaction: keto-phenylpyruvate + L-tyrosine  = L-phenylalanine  + 3-(4-hydroxyphenyl)pyruvate.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-15200									molecular_function											owl:Class	
GO:0032003	biolink:NamedThing	interleukin-28 receptor binding	Binding to an interleukin-28 receptor.	tmpzr1t_l9r_go_relaxed.owl	interleukin-28 receptor ligand|IL-28													molecular_function											owl:Class	
GO:0018757	biolink:NamedThing	deisopropylhydroxyatrazine aminohydrolase activity	Catalysis of the reaction: deisopropylhydroxyatrazine + H2O = NH3 + 2,4-dihydroxy-6-(N'-ethyl)amino-1,3,5-triazine.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0121|KEGG_REACTION:R05574									molecular_function											owl:Class	
GO:0051435	biolink:NamedThing	BH4 domain binding	Binding to a BH4 protein domain, present in Bcl-2 family members. All anti-apoptotic proteins contain BH1 and BH2 domains; some also contain an additional N-terminal BH4 domain, which is almost never seen in pro-apoptotic proteins. Loss of the BH4 domain can diminish or abrogate anti-apoptotic function or even impart outright death-promoting properties to the protein.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0071818	biolink:NamedThing	BAT3 complex	A protein complex found in mammals that transfers tail-anchored (TA) proteins from SGTA to GET3 (ASNA1/TRC4) for targeting to the endoplasmic reticulum membrane. Also chaperones polypeptides from the endoplasmic reticulum retrotranslocation machinery to the proteasome, maintaining the solubility of substrates to improve ER-associated protein degradation (ERAD). Consists of BAG6 (BAT3) and its cofactors GET4 (TRC35) and UBL4A.	tmpzr1t_l9r_go_relaxed.owl	BAG6-UBL4A-TRC35 complex|Bag6 complex|BAT3-TRC35-UBL4A complex	https://github.com/geneontology/go-ontology/issues/20919						mah	2010-09-07T11:01:38Z					cellular_component											owl:Class	
GO:0009978	biolink:NamedThing	allene oxide synthase activity	Catalysis of the reaction: 13(S)-hydroperoxylinolenate = 12,13(S)-epoxylinolenate + H2O.	tmpzr1t_l9r_go_relaxed.owl	hydroperoxide isomerase activity|linoleate hydroperoxide isomerase|linoleic acid hydroperoxide isomerase|(9Z,11E,14Z)-(13S)-hydroperoxyoctadeca-9,11,14-trienoate 12,13-hydro-lyase activity|HPI|(9Z,11E,14Z)-(13S)-hydroperoxyoctadeca-9,11,14-trienoate 12,13-hydro-lyase [(9Z)-(13S)-12,13-epoxyoctadeca-9,11-dienoate-forming]|hydroperoxide dehydratase activity				MetaCyc:HYDROPEROXIDE-DEHYDRATASE-RXN|MetaCyc:RXN1F-19|RHEA:25074|EC:4.2.1.92							GO:0047987		molecular_function											owl:Class	
GO:0102881	biolink:NamedThing	(+)-beta-barbatene synthase activity	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate <=> (+)-beta-barbatene + diphosphoric acid.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-8421									molecular_function											owl:Class	
GO:0008913	biolink:NamedThing	lauroyltransferase activity	Catalysis of the transfer of a lauroyl (dodecanoyl) group from one compound to another.	tmpzr1t_l9r_go_relaxed.owl	lauroyl transferase activity													molecular_function											owl:Class	
GO:0097748	biolink:NamedThing	3'-5' RNA polymerase activity	Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1); the synthesis of RNA from ribonucleotide triphosphates in the presence of a nucleic acid template, via extension of the 5'-end.	tmpzr1t_l9r_go_relaxed.owl					RHEA:57528			pr	2016-12-02T11:51:31Z					molecular_function											owl:Class	
GO:0071172	biolink:NamedThing	dihydromonapterin reductase activity	Catalysis of the reaction: 7,8-dihydromonapterin + NADPH = tetrahydromonapterin + NADP+.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-11-23T11:10:17Z					molecular_function											owl:Class	
GO:0047026	biolink:NamedThing	androsterone dehydrogenase (A-specific) activity	Catalysis of the reaction: NAD(P)+ + androsterone = NAD(P)H + H+ + 5-alpha-androstane-3,17-dione. The reaction is A-specific (i.e. the pro-R hydrogen is transferred from the 4-position of reduced nicotinamide cofactor) with respect to NAD(P)+.	tmpzr1t_l9r_go_relaxed.owl	3alpha-hydroxysteroid:NAD(P)+ oxidoreductase (A-specific)|3-alpha-hydroxysteroid dehydrogenase (A-specific) activity|3alpha-hydroxysteroid dehydrogenase (A-specific)				EC:1.1.1.213|Wikipedia:3alpha-hydroxysteroid_dehydrogenase_(A-specific)|MetaCyc:1.1.1.213-RXN									molecular_function											owl:Class	
GO:0070521	biolink:NamedThing	alpha4-beta1 integrin-CD82 complex	A protein complex that consists of an alpha4-beta1 integrin complex bound to membrane protein CD82, a member of the tetraspan family.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0048501	biolink:NamedThing	signal recognition particle, plasma membrane targeting	A complex consisting of a protein and RNA component which binds the signal sequence of some proteins and facilitates their export to or across the plasma membrane.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0001003	biolink:NamedThing	RNA polymerase III type 2 promoter sequence-specific DNA binding	Binding to a sequence of DNA that is a part of a type 2 promoter that controls transcription by RNA polymerase III. Type 2 promoters consist of an A box and a B box downstream of the transcription start site within the sequence within the sequence of the mature RNA. Type 2 promoters are found in many tRNA genes as well as in other small RNAs.	tmpzr1t_l9r_go_relaxed.owl	RNA polymerase III type 2 promoter DNA binding							krc	2010-08-18T05:51:18Z			GO:0001031		molecular_function											owl:Class	
GO:0035824	biolink:NamedThing	long tract gene conversion	A gene conversion process in which a segment of more than 1000 base pairs is transferred from the donor to the acceptor.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-05-04T01:06:18Z					biological_process											owl:Class	
GO:0030123	biolink:NamedThing	AP-3 adaptor complex	A heterotetrameric AP-type membrane coat adaptor complex that consists of beta3, delta, mu3 and sigma3 subunits and is found associated with endosomal membranes. AP-3 does not appear to associate with clathrin in all organisms. In at least humans, the AP-3 complex can be heterogeneric due to the existence of multiple subunit isoforms encoded by different genes (beta3A and beta3B, mu3A and mu3B, and sigma3A and sigma3B).	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:1905670	biolink:NamedThing	TORC2 complex disassembly	The disaggregation of a TORC2 complex into its constituent components.	tmpzr1t_l9r_go_relaxed.owl	mTORC2 disassembly|rapamycin and nutrient-insensitive TOR complex disassembly|TORC2 disassembly|TOR complex 2 disassembly|TORC 2 complex disassembly							kmv	2016-11-11T21:03:37Z					biological_process											owl:Class	
GO:0004635	biolink:NamedThing	phosphoribosyl-AMP cyclohydrolase activity	Catalysis of the reaction: 1-(5-phosphonatoribosyl)-5'-AMP + H(2)O = 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide.	tmpzr1t_l9r_go_relaxed.owl	1-(5-phospho-D-ribosyl)-AMP 1,6-hydrolase activity|phosphoribosyladenosine monophosphate cyclohydrolase activity|PRAMP-cyclohydrolase activity				EC:3.5.4.19|RHEA:20049|KEGG_REACTION:R04037|MetaCyc:HISTCYCLOHYD-RXN									molecular_function											owl:Class	
GO:0006108	biolink:NamedThing	malate metabolic process	The chemical reactions and pathways involving malate, the anion of hydroxybutanedioic acid, a chiral hydroxydicarboxylic acid. The (+) enantiomer is an important intermediate in metabolism as a component of both the TCA cycle and the glyoxylate cycle.	tmpzr1t_l9r_go_relaxed.owl	malate metabolism													biological_process											owl:Class	
GO:0031726	biolink:NamedThing	CCR1 chemokine receptor binding	Binding to a CCR1 chemokine receptor.	tmpzr1t_l9r_go_relaxed.owl	macrophage inflammatory protein-1 alpha receptor binding|CCR1 chemokine receptor ligand													molecular_function											owl:Class	
GO:1990623	biolink:NamedThing	Herring body	The dilated terminal portions of neurosecretory axons constituting the hypothalamohypophyseal tract, found in close proximity to sinusoidal capillaries in the posterior pituitary. Herring bodies consist of aggregates of membrane-bound neurosecretory vesicles where oxytocin or antidiuretic hormone (ADH) are stored prior to release. Each Herring body also contains ATP and either neurophysin I or neurophysin II which bind to oxytocin and ADH, respectively.	tmpzr1t_l9r_go_relaxed.owl	neurosecretory body							cls	2015-01-29T21:11:54Z					cellular_component											owl:Class	
GO:0036225	biolink:NamedThing	cellular response to vitamin B1 starvation	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of vitamin B1 (also called thiamin and thiamine).	tmpzr1t_l9r_go_relaxed.owl	cellular response to thiamin starvation|cellular response to vitamin B1 deprivation							bf	2012-05-09T02:35:55Z					biological_process											owl:Class	
GO:0050888	biolink:NamedThing	determination of stimulus location	The determination of where on the body surface, within the body or in the environment a stimulus originates.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0044589	biolink:NamedThing	pectin binding	Binding to pectin.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-04-26T01:26:56Z					molecular_function											owl:Class	
GO:0004475	biolink:NamedThing	mannose-1-phosphate guanylyltransferase activity	Catalysis of the reaction: alpha-D-mannose 1-phosphate + GTP = diphosphate + GDP-alpha-D-mannose.	tmpzr1t_l9r_go_relaxed.owl	PIM-GMP (phosphomannose isomerase-guanosine 5'-diphospho-D-mannose pyrophosphorylase)|guanosine 5'-diphospho-D-mannose pyrophosphorylase activity|GDP-mannose pyrophosphorylase activity|guanosine diphosphomannose pyrophosphorylase activity|GTP:mannose-1-phosphate guanylyltransferase activity|mannose 1-phosphate guanylyltransferase (guanosine triphosphate)|GTP:alpha-D-mannose-1-phosphate guanylyltransferase activity|GTP-mannose-1-phosphate guanylyltransferase activity|guanosine triphosphate-mannose 1-phosphate guanylyltransferase activity				KEGG_REACTION:R00885|MetaCyc:2.7.7.13-RXN|EC:2.7.7.13|RHEA:15229|Reactome:R-HSA-446221									molecular_function											owl:Class	
GO:0060826	biolink:NamedThing	transforming growth factor beta receptor signaling pathway involved in neural plate anterior/posterior pattern formation	A series of molecular signals initiated by the binding of an extracellular ligand to a transforming growth factor beta receptor on the surface of a target cell, which contributes to the formation of the neural plate anterior/posterior pattern.	tmpzr1t_l9r_go_relaxed.owl	transforming growth factor beta receptor signalling pathway involved in neural plate anterior/posterior pattern formation							dph	2009-08-11T01:43:29Z					biological_process											owl:Class	
GO:0015915	biolink:NamedThing	fatty-acyl group transport	The directed movement of fatty acyl groups into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A fatty acyl group is any acyl group derived from a fatty acid.	tmpzr1t_l9r_go_relaxed.owl	fatty acyl transport													biological_process											owl:Class	
GO:0032837	biolink:NamedThing	distributive segregation	The cell cycle process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets during a normally chiasmate meiosis under the condition that chiasma have not occurred between a particular pair of homologs. Distributive segregation is a backup mechanism to ensure the segregation of homologs that have failed to cross over - either as a consequence of mutation or not, as, for example, the 4th chromosome of Drosophila melanogaster (which never exchanges, presumably due to its small size) - but nevertheless segregate normally.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0004350	biolink:NamedThing	glutamate-5-semialdehyde dehydrogenase activity	Catalysis of the reaction: L-glutamate 5-semialdehyde + NADP(+) + phosphate = L-glutamyl 5-phosphate + H(+) + NADPH.	tmpzr1t_l9r_go_relaxed.owl	glutamate-phosphate reductase activity|gamma-glutamyl phosphate reductase activity|glutamate-gamma-semialdehyde dehydrogenase activity|gamma-glutamylphosphate reductase activity|L-glutamate-5-semialdehyde:NADP+ 5-oxidoreductase (phosphorylating)|glutamyl-gamma-semialdehyde dehydrogenase activity|glutamylphosphate reductase activity|beta-glutamylphosphate reductase activity|glutamate semialdehyde dehydrogenase activity				MetaCyc:GLUTSEMIALDEHYDROG-RXN|KEGG_REACTION:R03313|RHEA:19541|EC:1.2.1.41							GO:0001513		molecular_function											owl:Class	
GO:0047232	biolink:NamedThing	galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,6-N-acetylglucosaminyltransferase activity	Catalysis of the reaction: D-galactosyl-1,4-N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide + UDP-N-acetyl-D-glucosamine = N-acetyl-D-glucosaminyl-1,6-beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-beta-D-glucosyceramide + UDP.	tmpzr1t_l9r_go_relaxed.owl	UDP-N-acetyl-D-glucosamine:D-galactosyl-1,4-N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide beta-1,6-N-acetylglucosaminyltransferase activity|uridine diphosphoacetylglucosamine-acetyllactosaminide beta1->6-acetylglucosaminyltransferase				MetaCyc:2.4.1.164-RXN|EC:2.4.1.164									molecular_function											owl:Class	
GO:0033942	biolink:NamedThing	4-alpha-D-(1->4)-alpha-D-glucanotrehalose trehalohydrolase activity	Catalysis of the hydrolysis of alpha-(1->4)-D-glucosidic linkage in 4-alpha-D-{(1->4)-alpha-D-glucanosyl}n trehalose to yield trehalose and alpha-(1->4)-D-glucan.	tmpzr1t_l9r_go_relaxed.owl	4-alpha-D-{(1->4)-alpha-D-glucano}trehalose glucanohydrolase (trehalose-producing) activity|maltooligosyl trehalose trehalohydrolase activity|4-alpha-D-{(1,4)-alpha-D-glucano}trehalose glucanohydrolase (trehalose-producing) activity|malto-oligosyltrehalose trehalohydrolase activity				EC:3.2.1.141|MetaCyc:3.2.1.141-RXN									molecular_function											owl:Class	
GO:0034862	biolink:NamedThing	2,6-dihydroxybenzothiazole monooxygenase activity	Catalysis of the reaction: 2,6-dihydroxybenzothiazole + 1/2 O2 = 2,6,7-trihydroxybenzothiazole.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r1294									molecular_function											owl:Class	
GO:0010347	biolink:NamedThing	L-galactose-1-phosphate phosphatase activity	Catalysis of the reaction: L-galactose-1-phosphate + H2O = L-galactose + phosphate.	tmpzr1t_l9r_go_relaxed.owl					RHEA:26349|MetaCyc:RXNQT-4142									molecular_function											owl:Class	
GO:0018633	biolink:NamedThing	dimethyl sulfide monooxygenase activity	Catalysis of the reaction: dimethyl sulfide + NADH + O2 = NAD+ + OH- + methanethiol + formaldehyde.	tmpzr1t_l9r_go_relaxed.owl	dimethyl sulphide monooxygenase activity				EC:1.14.13.-|UM-BBD_reactionID:r0208									molecular_function											owl:Class	
GO:0090695	biolink:NamedThing	Wpl/Pds5 cohesin loading/unloading complex	A eukaryotically conserved heterodimeric protein complex (comprising Wings apart-like protein and the Pds5 Armadillo repeat cohesin associated protein) involved in the loading and unloading of a cohesin complex onto DNA.	tmpzr1t_l9r_go_relaxed.owl								tb	2016-08-24T17:09:11Z					cellular_component											owl:Class	
GO:0061320	biolink:NamedThing	pericardial nephrocyte differentiation	The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a pericardial nephrocyte. A pericardial nephrocyte is an insect renal cell that filters hemolymph and is found with other pericardial nephrocytes in two rows flanking the dorsal vessel. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.	tmpzr1t_l9r_go_relaxed.owl	pericardial cell differentiation							dph	2010-09-24T12:25:53Z			GO:0007513		biological_process											owl:Class	
GO:0047124	biolink:NamedThing	L-erythro-3,5-diaminohexanoate dehydrogenase activity	Catalysis of the reaction: (3S,5S)-3,5-diaminohexanoate + H(2)O + NAD(+) = (S)-5-amino-3-oxo-hexanoate + H(+) + NADH + NH(4)(+).	tmpzr1t_l9r_go_relaxed.owl	L-erythro-3,5-diaminohexanoate:NAD+ oxidoreductase (deaminating)|L-3,5-diaminohexanoate dehydrogenase activity				EC:1.4.1.11|KEGG_REACTION:R03349|MetaCyc:1.4.1.11-RXN|RHEA:19633									molecular_function											owl:Class	
GO:0098626	biolink:NamedThing	methylseleninic acid reductase activity	Catalysis of the reaction: NADPH + H+ + CH3SeO2H => NADP+ + CH3SeOH + H2O.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-5263616									molecular_function											owl:Class	
GO:0047665	biolink:NamedThing	aminolevulinate transaminase activity	Catalysis of the reaction: 5-aminolevulinate + pyruvate = 4,5-dioxopentanoate + L-alanine.	tmpzr1t_l9r_go_relaxed.owl	gamma,delta-dioxovaleric acid transaminase activity|L-alanine-4,5-dioxovalerate aminotransferase activity|L-alanine:4,5-dioxovaleric acid transaminase activity|4,5-dioxovalerate aminotransferase activity|4,5-dioxovaleric acid aminotransferase activity|aminolevulinic acid transaminase activity|4,5-dioxovaleric transaminase activity|gamma,delta-dioxovalerate aminotransferase activity|4,5-dioxovaleric acid transaminase activity|alanine:4,5-dioxovalerate aminotransferase activity|dioxovalerate transaminase activity|DOVA transaminase activity|alanine-dioxovalerate aminotransferase activity|alanine-gamma,delta-dioxovalerate aminotransferase activity|aminolevulinate aminotransferase activity|5-aminolevulinate:pyruvate aminotransferase activity|L-alanine:dioxovalerate transaminase activity|5-aminolevulinic acid transaminase activity				EC:2.6.1.43|MetaCyc:AMINOLEVULINATE-AMINOTRANSFERASE-RXN|RHEA:12480|KEGG_REACTION:R02271									molecular_function											owl:Class	
GO:0102351	biolink:NamedThing	gamma-aminobutyrate transaminase (glyoxylate dependent) activity	Catalysis of the reaction: gamma-aminobutyric acid  + 2-oxo monocarboxylic acid anion = 4-oxobutanoate + glycine.	tmpzr1t_l9r_go_relaxed.owl					EC:2.6.1.96|RHEA:32267|MetaCyc:RXN-13328									molecular_function											owl:Class	
GO:0043721	biolink:NamedThing	4-hydroxybutanoyl-CoA dehydratase activity	Catalysis of the reaction: 4-hydroxybutanoyl-CoA = vinylacetyl-CoA + H2O.	tmpzr1t_l9r_go_relaxed.owl	4-hydroxybutanoyl-CoA hydro-lyase|gamma-hydroxybutyryl-CoA dehydratase activity|4-hydroxybutyryl-CoA dehydratase activity|gamma-hydroxybutanoyl-CoA dehydratase activity				MetaCyc:RXN-8890|RHEA:26530|EC:4.2.1.120|KEGG_REACTION:R05337									molecular_function											owl:Class	
GO:0016656	biolink:NamedThing	monodehydroascorbate reductase (NADH) activity	Catalysis of the reaction: NADH + H+ + 2 monodehydroascorbate = NAD+ + 2 ascorbate.	tmpzr1t_l9r_go_relaxed.owl	MDAsA reductase (NADPH)|NADH:semidehydroascorbic acid oxidoreductase activity|NADH:ascorbate radical oxidoreductase activity|SDA reductase activity|NADH:AFR oxidoreductase activity|MDHA|NADH-semidehydroascorbate oxidoreductase activity|ascorbic free radical reductase activity|AFR-reductase activity|NADH:monodehydroascorbate oxidoreductase activity|semidehydroascorbate reductase activity|monodehydroascorbate reductase activity|AFR|ascorbate free radical reductase activity|ascorbate free-radical reductase activity				RHEA:14581|MetaCyc:1.6.5.4-RXN|EC:1.6.5.4									molecular_function											owl:Class	
GO:0070530	biolink:NamedThing	K63-linked polyubiquitin modification-dependent protein binding	Binding to a protein upon poly-ubiquitination formed by linkages between lysine residues at position 63 in the target protein.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:1990434	biolink:NamedThing	lower tip-link density	An electron-dense plaque at the lower end of a stereocilia tip link that provides the anchor in the stereocilia membrane at the tip of the stereocilium from which the tip link rises.	tmpzr1t_l9r_go_relaxed.owl	LTLD							sl	2014-07-30T16:34:34Z					cellular_component											owl:Class	
GO:0030014	biolink:NamedThing	CCR4-NOT complex	The Ccr4-Not complex is an eukaryotically conserved deadenylase that can initiate cytoplasmic mRNA decay, and reduce translation by releasing poly(A)-binding protein (Pab1/PABPC1). Ccr4-Not contains seven core subunits, including two poly(A)-specific exonucleases, Ccr4/CNOT6/CNOT6L and Caf1/Pop2/CNOT7/CNOT8.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:1990017	biolink:NamedThing	somatic portion of tanycyte	Portion of a tanycyte that lies within the ependyma and contains the nucleus. A tanycyte is a specialized elongated ventricular ependymal cell that has processes that extend to the outer, or pial, surface of the CNS.	tmpzr1t_l9r_go_relaxed.owl	somatic portion				NIF_Subcellular:sao401910342			pr	2012-12-19T15:19:25Z					cellular_component											owl:Class	
GO:0008771	biolink:NamedThing	[citrate (pro-3S)-lyase] ligase activity	Catalysis of the reaction: ATP + acetate + (citrate (pro-3S)-lyase) (thiol form) = AMP + diphosphate + (citrate (pro-3S)-lyase) (acetyl form).	tmpzr1t_l9r_go_relaxed.owl	acetate: SH-acyl-carrier-protein enzyme ligase (AMP)|citrate (pro-3S)-lyase ligase activity|citrate lyase synthetase activity|acetate:citrate-(pro-3S)-lyase(thiol-form) ligase (AMP-forming)|citrate lyase ligase activity|acetate:HS-citrate lyase ligase activity				EC:6.2.1.22|KEGG_REACTION:R04449|MetaCyc:CITC-RXN|RHEA:23788									molecular_function											owl:Class	
GO:0018670	biolink:NamedThing	4-aminobenzoate 1-monooxygenase activity	Catalysis of the reaction: 4-aminobenzoate + NADPH + H+ + O2 = 4-hydroxyaniline + NADP+ + H2O + CO2.	tmpzr1t_l9r_go_relaxed.owl	4-aminobenzoate monooxygenase activity|4-aminobenzoate dehydrogenase activity|4-aminobenzoate hydroxylase activity|4-aminobenzoate,NAD(P)H:oxygen oxidoreductase (1-hydroxylating, decarboxylating)				MetaCyc:4-AMINOBENZOATE-1-MONOOXYGENASE-RXN|EC:1.14.13.27|UM-BBD_reactionID:r0597									molecular_function											owl:Class	
GO:0070711	biolink:NamedThing	RNA adenosine-uridine insertion	The modification of an RNA molecule by insertion of an adenosine-uridine dinucleotide.	tmpzr1t_l9r_go_relaxed.owl	RNA AU insertion							mah	2009-06-08T05:16:39Z					biological_process											owl:Class	
GO:0010487	biolink:NamedThing	thermospermine synthase activity	Catalysis of the reaction: S-adenosyl-L-methioninamine + spermidine = S-methyl-5'-thioadenosine + thermospermine + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-11190|EC:2.5.1.79|RHEA:30515									molecular_function											owl:Class	
GO:0034360	biolink:NamedThing	chylomicron remnant	A lipoprotein particle that is derived from a mature chylomicron particle by the removal of triglycerides from the chylomicron core by lipoprotein lipase and the subsequent loss of surface components. It characteristically contains apolipoprotein E (APOE) and is cleared from the blood by the liver.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0045031	biolink:NamedThing	G protein-coupled ATP receptor activity	Combining with ATP and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.	tmpzr1t_l9r_go_relaxed.owl	ATP-activated adenosine receptor activity|ATP-activated nucleotide receptor activity													molecular_function											owl:Class	
GO:0034563	biolink:NamedThing	2,3-bis(4-hydroxyphenyl)-1,2-propanediol dioxygenase activity	Catalysis of the reaction: 2,3-bis(4-hydroxyphenyl)-1,2-propanediol + O2 = 4-hydroxyphenacyl alcohol + 4-hydroxybenzoate + 2 H+ + 2 e-.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0867									molecular_function											owl:Class	
GO:0010492	biolink:NamedThing	maintenance of shoot apical meristem identity	The process in which an organism retains a population of shoot apical meristem cells, preventing the commitment of all stem cell progeny to a differentiated cell fate.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0102590	biolink:NamedThing	delphinidin 3-O-rutinoside 7-O-glucosyltransferase (acyl-glucose dependent) activity	Catalysis of the reaction: delphinidin 3-O-rutinoside + 1-O-4-hydroxybenzoyl-beta-D-glucose <=> delphinidin 3-O-rutinoside-7-O-glucoside + 4-hydroxybenzoic acid + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-15351									molecular_function											owl:Class	
GO:1990685	biolink:NamedThing	HDL-containing protein-lipid-RNA complex	A protein-lipid-RNA complex containing separate high-density lipoprotein (HDL), lipid and RNA molecules. Separate in this context means not covalently bound to each other.	tmpzr1t_l9r_go_relaxed.owl						Examples of HDL-containing protein-lipid-RNA complexes are described in PMID:21423178 and PMID:23559634, both showing evidence that high-density lipoproteins (HDL) transport endogenous microRNAs (miRNAs) and deliver them to recipient cells with functional targeting capabilities. Also see fig. 1 in the review PMID:22028337. Not to be confused with GO:0034364 'high-density lipoprotein particle', which describes complexes of proteins and lipids only, without RNAs.		pr	2015-03-11T14:56:52Z					cellular_component											owl:Class	
GO:0031220	biolink:NamedThing	maltodextrin phosphorylase activity	Catalysis of the reaction: maltodextrin = glucose-1-phosphate.	tmpzr1t_l9r_go_relaxed.owl					RHEA:29691|MetaCyc:RXN0-5182|MetaCyc:RXN-9025									molecular_function											owl:Class	
GO:0004300	biolink:NamedThing	enoyl-CoA hydratase activity	Catalysis of the reaction: (3S)-3-hydroxyacyl-CoA = trans-2-enoyl-CoA + H2O.	tmpzr1t_l9r_go_relaxed.owl	enoyl coenzyme A hydrase (D)|2-octenoyl coenzyme A hydrase activity|short-chain enoyl-CoA hydratase activity|enoyl hydrase activity|acyl coenzyme A hydrase activity|(3S)-3-hydroxyacyl-CoA hydro-lyase activity|enoyl coenzyme A hydratase activity|ECH|D-3-hydroxyacyl-CoA dehydratase|beta-hydroxyacyl-CoA dehydrase activity|trans-2-enoyl-CoA hydratase activity|beta-hydroxyacid dehydrase activity|crotonyl hydrase activity|hydratase, enoyl coenzyme A|enoyl coenzyme A hydrase (L)|2-enoyl-CoA hydratase activity|enol-CoA hydratase activity|short chain enoyl coenzyme A hydratase activity|unsaturated acyl-CoA hydratase activity				UM-BBD_enzymeID:e0014|RHEA:16105|MetaCyc:ENOYL-COA-HYDRAT-RXN|Reactome:R-HSA-77344|Reactome:R-HSA-77301|Reactome:R-HSA-70870|Reactome:R-HSA-77325|Reactome:R-HSA-70830|Reactome:R-HSA-77314|Reactome:R-HSA-77333|EC:4.2.1.17|Reactome:R-HSA-77277|Reactome:R-HSA-77256							GO:0016510		molecular_function											owl:Class	
GO:0047876	biolink:NamedThing	endoglycosylceramidase activity	Catalysis of the reaction: H2O + oligoglycosylglucosylceramide = ceramide + oligoglycosylglucose.	tmpzr1t_l9r_go_relaxed.owl	oligoglycosylglucosylceramide glycohydrolase activity|EGCase activity|glycosyl-N-acetyl-sphingosine 1,1-beta-D-glucanohydrolase activity|endoglycoceramidase activity|endo-glucosylceramidase activity				MetaCyc:ENDOGLYCOSYLCERAMIDASE-RXN|RHEA:22288|EC:3.2.1.123									molecular_function											owl:Class	
GO:0019992	biolink:NamedThing	diacylglycerol binding	Binding to a diacylglycerol, a diester of glycerol and two fatty acids.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0102424	biolink:NamedThing	sesaminol-2-O-gentiobioside 1,6-glucosyltransferase activity	Catalysis of the reaction: (+)-sesaminol 2-O-beta-D-gentiobioside + UDP-alpha-D-glucose <=> (+)-sesaminol 2-O-beta-D-gentiotrioside + UDP + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-13821									molecular_function											owl:Class	
GO:0033828	biolink:NamedThing	glucosylglycerol-phosphate synthase activity	Catalysis of the reaction: sn-glycerol 3-phosphate + ADP-glucose = 2-O-(beta-D-glucosyl)-sn-glycerol 3-phosphate + ADP + H(+).	tmpzr1t_l9r_go_relaxed.owl	GG-phosphate synthase activity|ADP-glucose:sn-glycerol-3-phosphate 2-beta-D-glucosyltransferase activity|glucosyl-glycerol-phosphate synthase activity|ADPglucose:sn-glycerol-3-phosphate 2-beta-D-glucosyltransferase activity|GGPS				RHEA:12881|EC:2.4.1.213|KEGG_REACTION:R05328|MetaCyc:2.4.1.213-RXN									molecular_function											owl:Class	
GO:0018831	biolink:NamedThing	5-chloro-1,2,4-trihydroxybenzene dechlorinase activity	Catalysis of the reaction: 5-chloro-1,2,4-trihydroxybenzene = Cl- + H+ + 2-hydroxy-1,4-benzoquinone.	tmpzr1t_l9r_go_relaxed.owl					EC:4.5.1.-|UM-BBD_reactionID:r0666									molecular_function											owl:Class	
GO:0034540	biolink:NamedThing	3-monobromobisphenol A reductive dehalogenase activity	Catalysis of the reaction: 3-monobromobisphenol A + 2 H+ + 2 e- = bisphenol A + HBr.	tmpzr1t_l9r_go_relaxed.owl					EC:1.97.1.-|UM-BBD_reactionID:r0824									molecular_function											owl:Class	
GO:0046740	biolink:NamedThing	transport of virus in host, cell to cell	The transport of a virus between adjacent cells in a multicellular organism.	tmpzr1t_l9r_go_relaxed.owl	intercellular virus transport|spread of virus in host, cell to cell|spread of virus within host, cell to cell|viral spread within host, cell to cell|cell to cell spread of virus within host				VZ:1018									biological_process											owl:Class	
GO:0102843	biolink:NamedThing	1-18:2-2-16:0-monogalactosyldiacylglycerol desaturase activity (SN2-16:1 forming)	Catalysis of the reaction: 1-18:2-2-16:0-monogalactosyldiacylglycerol + O2 + a reduced electron acceptor = 1-18:2-2-16:1-monogalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-8304|EC:1.14.19.42|RHEA:46756									molecular_function											owl:Class	
GO:0032792	biolink:NamedThing	negative regulation of CREB transcription factor activity	Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of the transcription factor CREB.	tmpzr1t_l9r_go_relaxed.owl	CREB inhibitor|inhibition of CREB transcription factor													biological_process											owl:Class	
GO:0098561	biolink:NamedThing	methyl accepting chemotaxis protein complex	A transmembrane protein complex that consists of multiple methyl-accepting chemoreceptor protein subunits, a histidine kinase and a connector protein and which functions in the regulation of flagellar rotary motor activity in response to an external chemical stimulus.	tmpzr1t_l9r_go_relaxed.owl						A number of complexes of this class are found in E.coli.								cellular_component											owl:Class	
GO:0106036	biolink:NamedThing	assembly of apicomedial cortex actomyosin	A process which results in the assembly or arrangement of constituent parts apicomedial cortex actomyosin.	tmpzr1t_l9r_go_relaxed.owl								hjd	2017-07-12T16:57:06Z					biological_process											owl:Class	
GO:0002416	biolink:NamedThing	IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor	The process of transporting IgG immunoglobulin, via transcytosis using the FcRn (also known as the neonatal Fc receptor; gene name FCGRT), from apical surface of an epithelial cell to the basolateral surface or vice versa depending on the location. This process is used for uptake of IgG from the milk in the gut in rodents, for transplacental transport of IgG from mother to embryo in humans, and for maintenance of a steady-state distribution of IgG across epithelial boundaries in general in adult mammals.	tmpzr1t_l9r_go_relaxed.owl	IgG immunoglobulin transcytosis in epithelial cells mediated by neonatal immunoglobulin receptor|IgG antibody transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor													biological_process											owl:Class	
GO:0034611	biolink:NamedThing	oligoribonucleotidase activity	Catalysis of the exonucleolytic cleavage of oligoribonucleotides to yield ribonucleoside 5'-phosphates.	tmpzr1t_l9r_go_relaxed.owl	RNA oligonucleotidase activity				Reactome:R-HSA-9615042|Reactome:R-HSA-9009950									molecular_function											owl:Class	
GO:0106409	biolink:NamedThing	cyclic-di-AMP phosphodiesterase activity	Catalysis of the reaction: 3',3'-c-di-AMP + H2O = 5'-O-phosphonoadenylyl-(3'-5')-adenosine + H+.	tmpzr1t_l9r_go_relaxed.owl					EC:3.1.4.59|MetaCyc:RXN-19814|RHEA:54420			hjd	2021-10-29 14:57:11+00:00					molecular_function											owl:Class	
GO:0050081	biolink:NamedThing	maltose-6'-phosphate glucosidase activity	Catalysis of the reaction: H2O + maltose 6'-phosphate = D-glucose + D-glucose 6-phosphate.	tmpzr1t_l9r_go_relaxed.owl	maltose-6'-phosphate 6-phosphoglucohydrolase activity|phospho-alpha-glucosidase activity				MetaCyc:MALTOSE-6-PHOSPHATE-GLUCOSIDASE-RXN|RHEA:20421|EC:3.2.1.122									molecular_function											owl:Class	
GO:0019785	biolink:NamedThing	ISG15-specific protease activity	Catalysis of the hydrolysis of ISG15, a small ubiquitin-related modifier, from previously modified substrates.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-1678841|Reactome:R-HSA-5653786									molecular_function											owl:Class	
GO:0032810	biolink:NamedThing	sterol response element binding	Binding to a sterol response element (SRE), a nonpalindromic sequence found in the promoters of genes involved in lipid metabolism.	tmpzr1t_l9r_go_relaxed.owl	SRE binding					Note that as agreed during the transcription overhaul, terms specifying binding to specific transcription regulatory motifs are no longer being created. The level of specificity GO has decided to go to is the "core promoter", "core promoter proximal region" and "enhancer". To capture more detail, please consider using column 16.								molecular_function											owl:Class	
GO:0030153	biolink:NamedThing	bacteriocin immunity	A process that mediates resistance to a bacteriocin: any of a heterogeneous group of polypeptide antibiotics that are secreted by certain bacterial strains and are able to kill cells of other susceptible (frequently related) strains after adsorption at specific receptors on the cell surface. They include the colicins, and their mechanisms of action vary.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0071180	biolink:NamedThing	MAML3-RBP-Jkappa-ICN2 complex	A protein complex that consists of the intracellular domain of Notch2 (ICN2), the DNA-binding transcription factor RBP-Jkappa, and the transcriptional coactivator Mastermind-like-3 (MAML3); the complex is involved in transcriptional activation in response to Notch-mediated signaling.	tmpzr1t_l9r_go_relaxed.owl	MAML3-RBP-Jkappa-Notch2 complex							mah	2009-11-23T02:51:29Z					cellular_component											owl:Class	
GO:0047117	biolink:NamedThing	enoyl-[acyl-carrier-protein] reductase (NADPH, A-specific) activity	Catalysis of the reaction: acyl-[acyl-carrier protein] + NADP+ = trans-D2-enoyl-[acyl-carrier protein] + NADPH + H+.	tmpzr1t_l9r_go_relaxed.owl	enoyl-acyl-carrier-protein reductase (NADPH, A-specific)|enoyl-acyl carrier protein (reduced nicotinamide adenine dinucleotide phosphate) reductase activity|enoyl-[acyl-carrier protein] reductase (NADPH, A-specific) activity|enoyl-ACp reductase activity|acyl-acyl-carrier-protein:NADP+ oxidoreductase (A-specific)|enoyl-ACP reductase (NADPH, A-specific) activity				EC:1.3.1.39|MetaCyc:1.3.1.39-RXN									molecular_function											owl:Class	
GO:0005725	biolink:NamedThing	intercalary heterochromatin	Any of the regions of heterochromatin that form a reproducible set of dense bands scattered along the euchromatic arms in polytene chromosomes.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0050038	biolink:NamedThing	L-xylulose reductase (NADP+) activity	Catalysis of the reaction: NADP(+) + xylitol = L-xylulose + H(+) + NADPH.	tmpzr1t_l9r_go_relaxed.owl	L-xylulose reductase activity				EC:1.1.1.10|Reactome:R-HSA-5662851|MetaCyc:L-XYLULOSE-REDUCTASE-RXN|RHEA:17025|KEGG_REACTION:R01904|Reactome:R-HSA-5661240									molecular_function											owl:Class	
GO:0008930	biolink:NamedThing	methylthioadenosine nucleosidase activity	Catalysis of the reaction: methylthioadenosine + H2O = adenine + 5-methylthio-D-ribose.	tmpzr1t_l9r_go_relaxed.owl	MTA nucleosidase activity|5'-methylthioadenosine nucleosidase activity|S-methyl-5'-thioadenosine adeninehyrolase activity|MeSAdo nucleosidase activity|methylthioadenosine methylthioribohydrolase activity				RHEA:13617|EC:3.2.2.16|MetaCyc:METHYLTHIOADENOSINE-NUCLEOSIDASE-RXN									molecular_function											owl:Class	
GO:0031930	biolink:NamedThing	mitochondria-nucleus signaling pathway	A series of molecular signals that forms a pathway of communication from the mitochondria to the nucleus and initiates cellular changes in response to changes in mitochondrial function.	tmpzr1t_l9r_go_relaxed.owl	mitochondrial signaling pathway|mitochondrial signalling pathway|retrograde response|mitochondria-nucleus signal transduction													biological_process											owl:Class	
GO:0090689	biolink:NamedThing	cleavage furrow leading edge	The 'trough' of the cleavage furrow. This is the part of the cleavage furrow closest to the contractile ring.	tmpzr1t_l9r_go_relaxed.owl								tb	2016-07-26T16:00:10Z					cellular_component											owl:Class	
GO:0003883	biolink:NamedThing	CTP synthase activity	Catalysis of the reaction: ATP + UTP + NH3 = ADP + phosphate + CTP.	tmpzr1t_l9r_go_relaxed.owl	cytidine 5'-triphosphate synthetase activity|UTP--ammonia ligase activity|UTP:ammonia ligase (ADP-forming)|CTP synthetase activity|cytidine triphosphate synthetase activity|uridine triphosphate aminase activity				EC:6.3.4.2|MetaCyc:CTPSYN-RXN|Reactome:R-HSA-73647|RHEA:16597|Reactome:R-HSA-504054									molecular_function											owl:Class	
GO:0015856	biolink:NamedThing	cytosine transport	The directed movement of cytosine, 4-amino-2-hydroxypyrimidine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	cytosine transmembrane transport													biological_process											owl:Class	
GO:0003881	biolink:NamedThing	CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity	Catalysis of the reaction: myo-inositol + CDP-diacylglycerol = 1-phosphatidyl-1D-myo-inositol + CMP + H(+).	tmpzr1t_l9r_go_relaxed.owl	phosphatidylinositol synthase activity|CDP-diglyceride-inositol transferase activity|CDP-diacylglycerol:myo-inositol-3-phosphatidyltransferase activity|CDP diglyceride-inositol phosphatidyltransferase activity|cytidine diphosphodiglyceride-inositol phosphatidyltransferase activity|CDP-DG:inositol transferase activity|CDP-diacylglycerol:myo-inositol 3-phosphatidyltransferase activity|CDP-diglyceride:inositol transferase activity|CDPdiacylglycerol-inositol 3-phosphatidyltransferase activity|cytidine 5'-diphospho-1,2-diacyl-sn-glycerol:myo-inositol 3-phosphatidyltransferase activity|cytidine diphosphoglyceride-inositol transferase activity|CDP-diacylglycerol--inositol phosphatidyltransferase activity|cytidine diphosphoglyceride-inositol phosphatidyltransferase activity				KEGG_REACTION:R01802|RHEA:11580|MetaCyc:2.7.8.11-RXN|Reactome:R-HSA-1482976|EC:2.7.8.11									molecular_function											owl:Class	
GO:0080061	biolink:NamedThing	indole-3-acetonitrile nitrilase activity	Catalysis of the reaction: indole-3-acetonitrile + 2 H2O = indole-3-acetic acid + NH3.	tmpzr1t_l9r_go_relaxed.owl					EC:3.5.5.1|RHEA:45776|MetaCyc:RXN-1404			dhl	2009-04-13T03:30:42Z					molecular_function											owl:Class	
GO:0140595	biolink:NamedThing	MIM complex	A large mitochondrial outer membrane translocase complex that mediates transport of proteins into mitochondrial compartments. MIM constitutes the major integration site for alpha-helical embedded proteins. In yeast, consists oof Mim1 and Mim2.	tmpzr1t_l9r_go_relaxed.owl	mitochondrial outer import machinery	https://github.com/geneontology/go-ontology/issues/20669						pg	2021-02-09T19:34:16Z					cellular_component											owl:Class	
GO:0061755	biolink:NamedThing	positive regulation of circulating fibrinogen levels	Any process that increases the quantity of fibrinogen circulating in the bloodstream.	tmpzr1t_l9r_go_relaxed.owl								dph	2016-02-29T16:26:49Z					biological_process											owl:Class	
GO:0061368	biolink:NamedThing	behavioral response to formalin induced pain	Any process that results in a change in the behaviour of an organism as a result of a formalin pain stimulus.	tmpzr1t_l9r_go_relaxed.owl								dph	2010-10-21T03:29:48Z					biological_process											owl:Class	
GO:0010184	biolink:NamedThing	cytokinin transport	The directed movement of cytokinins, a class of adenine-derived compounds that can function in plants as growth regulators, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0102128	biolink:NamedThing	chalcone synthase activity	Catalysis of the reaction: 4-dihydrocoumaroyl-CoA + 3 malonyl-CoA + 3 H+ = phloretin + 4 coenzyme A + 3 carbon dioxide.	tmpzr1t_l9r_go_relaxed.owl					EC:2.3.1.74|MetaCyc:RXN-11468									molecular_function											owl:Class	
GO:0035651	biolink:NamedThing	AP-3 adaptor complex binding	Binding to an AP-3 adaptor complex. The AP-3 adaptor complex is a heterotetrameric AP-type membrane coat adaptor complex that consists of beta3, delta, mu3 and sigma3 subunits and is found associated with endosomal membranes. In at least humans, the AP-3 complex can be heterogeneric due to the existence of multiple subunit isoforms encoded by different genes (beta3A and beta3B, mu3A and mu3B, and sigma3A and sigma3B).	tmpzr1t_l9r_go_relaxed.owl								bf	2011-01-25T10:59:36Z					molecular_function											owl:Class	
GO:1990535	biolink:NamedThing	neuron projection maintenance	The organization process that preserves a neuron projection in a stable functional or structural state. A neuron projection is a prolongation or process extending from a nerve cell, e.g. an axon or dendrite.	tmpzr1t_l9r_go_relaxed.owl	neuron process maintenance|neuron protrusion maintenance|axon maintenance|neurite maintenance|axon homeostasis|neuronal cell projection maintenance							kmv	2014-11-13T22:24:05Z					biological_process											owl:Class	
GO:0080165	biolink:NamedThing	callose deposition in phloem sieve plate	Any process in which callose is transported to, and/or maintained in, phloem sieve plate. Callose is a linear 1,3-beta-d-glucan formed from UDP-glucose and is found in certain plant cell walls.	tmpzr1t_l9r_go_relaxed.owl								dhl	2010-09-23T04:12:49Z					biological_process											owl:Class	
GO:0033976	biolink:NamedThing	2-haloacid dehalogenase (configuration-inverting) activity	Catalysis of the reactions: (S)-2-haloacid + H2O = (R)-2-hydroxyacid + halide, and (R)-2-haloacid + H2O = (S)-2-hydroxyacid + halide.	tmpzr1t_l9r_go_relaxed.owl	DL-2-haloacid halidohydrolase (inversion of configuration) activity|DL-DEXi|2-haloalkanoic acid dehalogenase activity|DL-2-haloacid dehalogenase (inversion of configuration) activity|2-haloalkanoid acid halidohydrolase activity|DL-2-haloacid dehalogenase activity				MetaCyc:3.8.1.10-RXN									molecular_function											owl:Class	
GO:0033908	biolink:NamedThing	beta-L-rhamnosidase activity	Catalysis of the hydrolysis of terminal, non-reducing beta-L-rhamnose residues in beta-L-rhamnosides.	tmpzr1t_l9r_go_relaxed.owl	beta-L-rhamnoside rhamnohydrolase activity				MetaCyc:3.2.1.43-RXN|EC:3.2.1.43									molecular_function											owl:Class	
GO:0106344	biolink:NamedThing	4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase activity from histidine and PLP	Catalysis of the reaction: 2 Fe(3+) + 4 H2O + L-histidyl-[4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase] + N(6)-(pyridoxal phosphate)-L-lysyl-[4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase] = (2S)-2-amino-5-hydroxy-4-oxopentanoyl-[4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase] + 3-oxopropanoate + 4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine + 2 Fe(2+) + 2 H(+) + L-lysyl-[4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase].	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/20274			RHEA:65756			hjd	2020-12-04T14:48:37Z					molecular_function											owl:Class	
GO:0102749	biolink:NamedThing	dihydrogeranylgeranyl-chlorophyll a reductase activity	Catalysis of the reaction: H+ + dihydrogeranylgeranyl-chlorophyll a + NADPH = tetrahydrogeranylgeranyl-chlorophyll a + NADP.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-7665									molecular_function											owl:Class	
GO:0043906	biolink:NamedThing	Ala-tRNA(Pro) hydrolase activity	Catalysis of the hydrolysis of misacylated Ala-tRNA(Pro).	tmpzr1t_l9r_go_relaxed.owl	Ala-tRNAPro hydrolase activity				EC:3.1.1.-									molecular_function											owl:Class	
GO:0033437	biolink:NamedThing	ACU codon-amino acid adaptor activity	A triplet codon-amino acid adaptor activity that recognizes an ACU codon.	tmpzr1t_l9r_go_relaxed.owl	ACT codon-amino acid adaptor activity|threonine tRNA					Note that in the standard genetic code, ACT codes for threonine.								molecular_function											owl:Class	
GO:0106405	biolink:NamedThing	isoprenoid diphosphate phosphatase activity	Catalysis of the dephosphorylation of isoprenoid diphosphates.	tmpzr1t_l9r_go_relaxed.owl								hjd	2021-10-13 20:29:36+00:00					molecular_function											owl:Class	
GO:0043718	biolink:NamedThing	2-hydroxymethylglutarate dehydrogenase activity	Catalysis of the reaction: 2-(hydroxymethyl)glutarate + NAD(+) = 2-formylglutarate + H(+) + NADH.	tmpzr1t_l9r_go_relaxed.owl	HgD|(S)-2-hydroxymethylglutarate:NAD+ oxidoreductase activity				Wikipedia:2-hydroxymethylglutarate_dehydrogenase|KEGG_REACTION:R07985|RHEA:15505|MetaCyc:1.1.1.291-RXN|EC:1.1.1.291									molecular_function											owl:Class	
GO:0018612	biolink:NamedThing	dibenzothiophene dioxygenase activity	Catalysis of the reaction: dibenzothiophene + NADH + O2 + H+ = NAD+ + cis-1,2-dihydroxy-1,2-dihydrodibenzothiophene.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0160|EC:1.14.12.-									molecular_function											owl:Class	
GO:0052934	biolink:NamedThing	alcohol dehydrogenase (cytochrome c) activity	Catalysis of the reaction: 2 [Fe(III)cytochrome c] + a primary alcohol = 2 [Fe(II)cytochrome c] + an aldehyde + 2 H+.	tmpzr1t_l9r_go_relaxed.owl	PQQ-dependent alcohol dehydrogenase activity|quinoprotein alcohol dehydrogenase activity|2-chloroethanol:cytochrome c oxidoreductase activity|alcohol dehydrogenase (acceptor) activity|alcohol:acceptor oxidoreductase activity|ethanol:cytochrome c oxidoreductase activity|alcohol:(acceptor) oxidoreductase activity|alcohol:cytochrome c oxidoreductase activity	https://github.com/geneontology/go-ontology/issues/21412			KEGG_REACTION:R05285|UM-BBD_enzymeID:e0004|EC:1.1.2.8|KEGG_REACTION:R05198|MetaCyc:RXN-11333|RHEA:51020							GO:0018468|GO:0052935|GO:0052936		molecular_function											owl:Class	
GO:0102294	biolink:NamedThing	cholesterol dehydrogenase activity	Catalysis of the reaction: cholesterol + NAD = cholest-5-en-3-one + NADH + H+.	tmpzr1t_l9r_go_relaxed.owl					RHEA:35459|EC:1.1.1.145|MetaCyc:RXN-12693									molecular_function											owl:Class	
GO:0019799	biolink:NamedThing	tubulin N-acetyltransferase activity	Catalysis of the reaction: acetyl-CoA + (alpha-tubulin) L-lysine = CoA + (alpha-tubulin) N6-acetyl-L-lysine.	tmpzr1t_l9r_go_relaxed.owl	tubulin acetyltransferase activity|acetyl-CoA:alpha-tubulin-L-lysine N6-acetyltransferase activity|alpha-tubulin N-acetyltransferase activity|TAT activity|acetyl-CoA:alpha-tubulin-L-lysine 6-N-acetyltransferase activity|alpha-tubulin acetyltransferase activity|acetyl-CoA:alpha-tubulin-lysine N-acetyltransferase activity|alpha-tubulin acetylase activity				RHEA:15277|MetaCyc:TUBULIN-N-ACETYLTRANSFERASE-RXN|EC:2.3.1.108									molecular_function											owl:Class	
GO:0033814	biolink:NamedThing	propanoyl-CoA C-acyltransferase activity	Catalysis of the reaction: 3alpha,7alpha,12alpha-trihydroxy-5beta-cholanoyl-CoA + propanoyl-CoA = CoA + 3alpha,7alpha,12alpha-trihydroxy-24-oxo-5beta-cholestanoyl-CoA.	tmpzr1t_l9r_go_relaxed.owl	sterol carrier protein-chi|sterol carrier protein-X|SCP-X|3alpha,7alpha,12alpha-trihydroxy-5beta-cholanoyl-CoA:propanoyl-CoA C-acyltransferase activity|peroxisomal thiolase 2 activity|PTE-2|SCPchi				RHEA:16865|EC:2.3.1.176|MetaCyc:2.3.1.176-RXN									molecular_function											owl:Class	
GO:0106296	biolink:NamedThing	D-series resolvin biosynthetic process	The chemical reactions and pathways resulting in the formation of resolvin family D-series, hydroxy fatty acids derived from docosahexaenoic acid.	tmpzr1t_l9r_go_relaxed.owl								hjd	2020-08-25T13:48:32Z					biological_process											owl:Class	
GO:0051371	biolink:NamedThing	muscle alpha-actinin binding	Binding to muscle isoforms of actinin. Muscle alpha-actinin isoforms are found in skeletal and cardiac muscle and are localized to the Z-disc.	tmpzr1t_l9r_go_relaxed.owl	alpha-actinin 2 binding|alpha-actinin 3 binding													molecular_function											owl:Class	
GO:0071713	biolink:NamedThing	para-aminobenzoyl-glutamate hydrolase activity	Catalysis of the reaction: para-aminobenzoyl-glutamate + H2O = para-aminobenzoate + L-glutamate.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-03-10T01:25:31Z					molecular_function											owl:Class	
GO:0034891	biolink:NamedThing	endosulfan diol dehydrogenase activity	Catalysis of the reaction: endosulfan diol = endosulfan hydroxyether + 2 H+ + 2 e-.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r1388									molecular_function											owl:Class	
GO:0090541	biolink:NamedThing	MIT domain binding	Binding to a MIT protein domain. The MIT domain is found in vacuolar sorting proteins, spastin (probable ATPase involved in the assembly or function of nuclear protein complexes), and a sorting nexin, which may play a role in intracellular trafficking.	tmpzr1t_l9r_go_relaxed.owl								tb	2013-02-14T17:11:29Z					molecular_function											owl:Class	
GO:1990957	biolink:NamedThing	NPHP complex	A protein complex that is located at the ciliary transition zone and consists of the NPHP4 and NPHP1 proteins. It acts as an organiser of the transition zone inner structure, specifically the Y-shaped links, in conjunction with the MKS complex. It is involved in ciliary protein trafficking and is required for correct functioning of the WNT and Hippo signaling pathways.	tmpzr1t_l9r_go_relaxed.owl	NPHP module					Although there is some evidence, it's still unclear if the MKS and NPHP complexes are constituent parts of the ciliary Y-shaped links or are simply responsible for aligning and attaching the Y-shaped links to the cilium membrane and axoneme.		pr	2016-06-06T10:59:45Z					cellular_component											owl:Class	
GO:0047218	biolink:NamedThing	hydroxycinnamate 4-beta-glucosyltransferase activity	Catalysis of the reaction: 4-coumarate + UDP-D-glucose = 4-O-beta-D-glucosyl-4-hydroxycinnamate + UDP.	tmpzr1t_l9r_go_relaxed.owl	UDPglucose:trans-4-hydroxycinnamate 4-O-beta-D-glucosyltransferase activity|uridine diphosphoglucose-hydroxycinnamate glucosyltransferase activity|UDP-glucose-hydroxycinnamate glucosyltransferase activity|UDP-glucose:trans-4-hydroxycinnamate 4-O-beta-D-glucosyltransferase activity|hydroxycinnamoyl glucosyltransferase activity				EC:2.4.1.126|RHEA:21636|MetaCyc:2.4.1.126-RXN									molecular_function											owl:Class	
GO:0106110	biolink:NamedThing	vomitoxin biosynthetic process	The chemical reactions and pathways resulting in the formation of type B trichothecene vomitoxin, a poisonous substance produced by some species of fungi and predominantly occurs in grains such as wheat, barley and oats.	tmpzr1t_l9r_go_relaxed.owl	DON biosynthetic process|vomitoxin anabolism|vomitoxin biosynthesis|vomitoxin synthesis|vomitoxin formation|deoxynivalenol biosynthetic process							hjd	2018-04-16T19:06:06Z					biological_process											owl:Class	
GO:0034844	biolink:NamedThing	naphthyl-2-methyl-succinate CoA-transferase activity	Catalysis of the reaction: naphthyl-2-methyl-succinate + succinyl-CoA = naphthyl-2-methyl-succinyl-CoA + succinate.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r1256									molecular_function											owl:Class	
GO:0018836	biolink:NamedThing	alkylmercury lyase activity	Catalysis of the reaction: R-Hg+ + H+ = R-H + Hg2+.	tmpzr1t_l9r_go_relaxed.owl	alkylmercury mercuric-lyase (alkane-forming)|organomercurial lyase activity|alkylmercury mercuric-lyase activity|organomercury lyase activity				MetaCyc:ALKYLMERCURY-LYASE-RXN|EC:4.99.1.2|RHEA:18777|UM-BBD_enzymeID:e0055									molecular_function											owl:Class	
GO:0003853	biolink:NamedThing	2-methylacyl-CoA dehydrogenase activity	Catalysis of the reaction: 2-methylbutanoyl-CoA + acceptor = 2-methylbut-2-enoyl-CoA + reduced acceptor.	tmpzr1t_l9r_go_relaxed.owl	2-methylbutanoyl-CoA:(acceptor) oxidoreductase activity|2-methylbutanoyl-CoA:acceptor oxidoreductase activity|2-methyl branched chain acyl-CoA dehydrogenase activity|branched-chain acyl-CoA dehydrogenase activity				RHEA:13261|EC:1.3.99.12|MetaCyc:2-METHYLACYL-COA-DEHYDROGENASE-RXN									molecular_function											owl:Class	
GO:0018636	biolink:NamedThing	phenanthrene 9,10-monooxygenase activity	Catalysis of the reaction: phenanthrene + O2 + NADH + H+ = H2O + NAD+ + phenanthrene-9,10-oxide.	tmpzr1t_l9r_go_relaxed.owl					EC:1.14.13.-|UM-BBD_reactionID:r0495									molecular_function											owl:Class	
GO:0004394	biolink:NamedThing	heparan sulfate 2-O-sulfotransferase activity	Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + heparan sulfate = adenosine 3',5'-bisphosphate + heparan sulfate 2-O-sulfate; results in 2-O-sulfation of iduronic acid residues in heparan sulfate.	tmpzr1t_l9r_go_relaxed.owl	heparan-sulfate 2-O-sulphotransferase activity|heparin 2-sulfotransferase activity|heparin-sulphate 2-sulphotransferase activity				EC:2.8.2.-|Reactome:R-HSA-2076508									molecular_function											owl:Class	
GO:0071208	biolink:NamedThing	histone pre-mRNA DCP binding	Binding to the downstream cleavage product (DCP) generated by histone pre-mRNA 3'-end processing.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-11-25T01:41:35Z					molecular_function											owl:Class	
GO:0061693	biolink:NamedThing	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity	Catalysis of the reaction: ATP + methylphosphonate = alpha-D-ribose 1-methylphosphonate 5-triphosphate + adenine.	tmpzr1t_l9r_go_relaxed.owl					EC:2.7.8.37|RHEA:34679|MetaCyc:RXN0-6732			dph	2015-05-06T10:04:04Z					molecular_function											owl:Class	
GO:0016532	biolink:NamedThing	superoxide dismutase copper chaperone activity	A copper chaperone activity that specifically delivers copper to the Cu-Zn superoxide dismutase, to activate superoxide dismutase activity.	tmpzr1t_l9r_go_relaxed.owl						See also the molecular function term 'superoxide dismutase activity ; GO:0004784'.								molecular_function											owl:Class	
GO:0008255	biolink:NamedThing	ecdysis-triggering hormone activity	The action characteristic of ecdysis-triggering hormone, a peptide hormone that, upon receptor binding, initiates pre-ecdysis and ecdysis (i.e. cuticle shedding) through direct action on the central nervous system.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0004491	biolink:NamedThing	methylmalonate-semialdehyde dehydrogenase (acylating) activity	Catalysis of the reaction: 2-methyl-3-oxopropanoate + CoA + NAD+ = propanoyl-CoA + CO2 + NADH + H+.	tmpzr1t_l9r_go_relaxed.owl	MSDH activity|2-methyl-3-oxopropanoate:NAD+ 3-oxidoreductase (CoA-propanoylating)|MMSA dehydrogenase activity				RHEA:20804|Reactome:R-HSA-70893|EC:1.2.1.27|MetaCyc:1.2.1.27-RXN									molecular_function											owl:Class	
GO:0102967	biolink:NamedThing	10-hydroxygeraniol oxidoreductase activity	Catalysis of the reaction: (6E)-8-hydroxygeraniol + NADP <=> (6E)-8-hydroxygeranial + NADPH + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-9367|RHEA:32607									molecular_function											owl:Class	
GO:0016719	biolink:NamedThing	carotene 7,8-desaturase activity	Catalysis of the reaction: neurosporene + donor-H2 + O2 = lycopene + acceptor + 2 H2O.	tmpzr1t_l9r_go_relaxed.owl	zeta-carotene desaturase activity|carotene,hydrogen-donor:oxygen oxidoreductase activity				EC:1.3.5.6|MetaCyc:1.14.99.30-RXN|RHEA:15701									molecular_function											owl:Class	
GO:0050045	biolink:NamedThing	laminaribiose phosphorylase activity	Catalysis of the reaction: 3-beta-D-glucosyl-D-glucose + phosphate = D-glucose + alpha-D-glucose 1-phosphate.	tmpzr1t_l9r_go_relaxed.owl	3-beta-D-glucosyl-D-glucose:phosphate alpha-D-glucosyltransferase activity				MetaCyc:LAMINARIBIOSE-PHOSPHORYLASE-RXN|EC:2.4.1.31|RHEA:16617									molecular_function											owl:Class	
GO:0047815	biolink:NamedThing	D-arabinonolactonase activity	Catalysis of the reaction: D-arabinono-1,4-lactone + H(2)O = D-arabinonate + H(+).	tmpzr1t_l9r_go_relaxed.owl	D-arabinono-1,4-lactone lactonohydrolase activity				MetaCyc:D-ARABINONOLACTONASE-RXN|EC:3.1.1.30|RHEA:23108|KEGG_REACTION:R02714									molecular_function											owl:Class	
GO:0097122	biolink:NamedThing	cyclin A2-CDK1 complex	A protein complex consisting of cyclin A2 and cyclin-dependent kinase 1 (CDK1). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner.	tmpzr1t_l9r_go_relaxed.owl								pr	2011-08-01T01:42:24Z					cellular_component											owl:Class	
GO:0000236	biolink:NamedThing	mitotic prometaphase	The cell cycle phase in higher eukaryotes which follows mitotic prophase and during which the nuclear envelope is disrupted and breaks into membrane vesicles, and the spindle microtubules enter the nuclear region. Kinetochores mature on each centromere and attach to some of the spindle microtubules. Kinetochore microtubules begin the process of aligning chromosomes in one plane halfway between the poles.	tmpzr1t_l9r_go_relaxed.owl						Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).								biological_process											owl:Class	
GO:0021926	biolink:NamedThing	Golgi cell precursor proliferation	The multiplication or reproduction of neuroblasts that will give rise to Golgi cells. A Golgi cell is an inhibitory GABAergic interneuron found in the cerebellar cortex.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0018825	biolink:NamedThing	triethanolamine lyase activity	Catalysis of the reaction: triethanolamine = diethanolamine + acetaldehyde.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_enzymeID:e0421									molecular_function											owl:Class	
GO:0097431	biolink:NamedThing	mitotic spindle pole	Either of the ends of a mitotic spindle, a spindle that forms as part of mitosis, where spindle microtubules are organized; usually contains a microtubule organizing center and accessory molecules, spindle microtubules and astral microtubules.	tmpzr1t_l9r_go_relaxed.owl								pr	2012-11-20T09:03:16Z					cellular_component											owl:Class	
GO:0044398	biolink:NamedThing	envenomation resulting in induction of edema in other organism	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the swelling of soft tissues of the bitten organism as a result of excess water accumulation.	tmpzr1t_l9r_go_relaxed.owl	envenomation resulting in induction of oedema in other organism							jl	2011-12-21T03:57:27Z					biological_process											owl:Class	
GO:1990400	biolink:NamedThing	mitochondrial ribosomal large subunit rRNA binding	Binding to a mitochondrial large ribosomal subunit RNA (LSU rRNA).	tmpzr1t_l9r_go_relaxed.owl	21S rRNA binding|mitochondrial LSU rRNA binding					In S. cerevisiae, this is the mitochondrial 21S rRNA		mcc	2014-06-23T16:47:09Z					molecular_function											owl:Class	
GO:0102668	biolink:NamedThing	liquiritigenin,NADPH:oxygen oxidoreductase activity	Catalysis of the reaction: liquiritigenin + NADPH + O2 + H+ <=> 2,4',7-trihydroxyisoflavanone + NADP(3-) + H2O.	tmpzr1t_l9r_go_relaxed.owl					RHEA:31723|MetaCyc:RXN-3283|EC:1.14.14.87									molecular_function											owl:Class	
GO:0019232	biolink:NamedThing	perception of rate of movement	The series of events by which an organism senses the speed and direction of movement of the body and its parts.	tmpzr1t_l9r_go_relaxed.owl	kinesthesia													biological_process											owl:Class	
GO:0060020	biolink:NamedThing	Bergmann glial cell differentiation	The process in which neuroepithelial cells of the neural tube give rise to Brgmann glial cells, specialized bipotential progenitors cells of the cerebellum. Differentiation includes the processes involved in commitment of a cell to a specific fate.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1990577	biolink:NamedThing	C-terminal protein demethylation	The removal of a methyl group from the C-terminal amino acid of a protein.	tmpzr1t_l9r_go_relaxed.owl								mcc	2014-12-08T20:55:17Z					biological_process											owl:Class	
GO:0070260	biolink:NamedThing	5'-tyrosyl-DNA phosphodiesterase activity	Catalysis of the hydrolysis of 5'-phosphotyrosyl groups formed as covalent intermediates (in DNA backbone breakage) between DNA topoisomerase II and DNA.	tmpzr1t_l9r_go_relaxed.owl						See also the molecular function term 'DNA topoisomerase type I activity ; GO:0003917'.								molecular_function											owl:Class	
GO:0019726	biolink:NamedThing	mevaldate reductase (NADPH) activity	Catalysis of the reaction: (R)-mevalonate + NADP(+) = H(+) + mevaldate + NADPH.	tmpzr1t_l9r_go_relaxed.owl	mevaldate (reduced nicotinamide adenine dinucleotide phosphate) reductase|(R)-mevalonate:NADP+ oxidoreductase				EC:1.1.1.33|MetaCyc:MEVALDATE-REDUCTASE-NADPH-RXN|RHEA:20193|KEGG_REACTION:R02247									molecular_function											owl:Class	
GO:0008157	biolink:NamedThing	protein phosphatase 1 binding	Binding to a protein phosphatase 1.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0018586	biolink:NamedThing	mono-butyltin dioxygenase activity	Catalysis of the reaction: butyltin + O2 + 2 H+ + 2 e- = H2O + beta-hydroxybutyltin.	tmpzr1t_l9r_go_relaxed.owl	MBT dioxygenase activity				UM-BBD_reactionID:r0647									molecular_function											owl:Class	
GO:0003347	biolink:NamedThing	epicardial cell to mesenchymal cell transition	A transition where an epicardial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell. The epicardium is a part of the pericardium.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-12-01T11:05:39Z					biological_process											owl:Class	
GO:0033000	biolink:NamedThing	Fc-gamma receptor I complex	A protein complex composed of an Fc-gamma RI alpha chain and an Fc-epsilon RI gamma chain dimer with or without additional signaling components. The complex functions primarily as an activating receptor for IgG.	tmpzr1t_l9r_go_relaxed.owl	FcgRI complex|IgG receptor complex|immunoglobulin G receptor complex													cellular_component											owl:Class	
GO:0032039	biolink:NamedThing	integrator complex	A protein complex that stably associates with the C-terminus of RNA polymerase II and mediates 3'-end processing of small nuclear RNAs generated by RNA polymerase II.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/15979												cellular_component											owl:Class	
GO:0018551	biolink:NamedThing	hydrogensulfite reductase activity	Catalysis of the reaction: trithionate + acceptor + 2 H2O + OH- = 3 HSO3- + reduced acceptor.	tmpzr1t_l9r_go_relaxed.owl	trithionate:acceptor oxidoreductase activity|bisulfite reductase activity|dissimilatory sulfite reductase activity|desulfoviridin activity|dissimilatory-type sulfite reductase activity|hydrogensulphite reductase activity|trithionate:(acceptor) oxidoreductase activity|desulfofuscidin activity|desulforubidin activity				UM-BBD_reactionID:r0627|MetaCyc:HYDROGENSULFITE-REDUCTASE-RXN|EC:1.8.99.3|RHEA:13209									molecular_function											owl:Class	
GO:0047922	biolink:NamedThing	gentisate 1,2-dioxygenase activity	Catalysis of the reaction: 2,5-dihydroxybenzoate + O(2) = 3-maleylpyruvate + H(+).	tmpzr1t_l9r_go_relaxed.owl	gentisate oxygenase activity|gentisic acid oxidase activity|gentisate dioxygenase activity|2,5-dihydroxybenzoate dioxygenase activity|gentisate:oxygen 1,2-oxidoreductase (decyclizing)				RHEA:18237|KEGG_REACTION:R02656|EC:1.13.11.4|MetaCyc:GENTISATE-12-DIOXYGENASE-RXN									molecular_function											owl:Class	
GO:0018694	biolink:NamedThing	p-cymene methyl hydroxylase activity	Catalysis of the reaction: p-cymene + NADH + O2 = NAD+ + OH- + p-cumic alcohol.	tmpzr1t_l9r_go_relaxed.owl					EC:1.14.15.25|UM-BBD_reactionID:r0392|MetaCyc:RXN-661|RHEA:51604									molecular_function											owl:Class	
GO:0047384	biolink:NamedThing	[hydroxymethylglutaryl-CoA reductase (NADPH)]-phosphatase activity	Catalysis of the reaction: H2O + [hydroxymethylglutaryl-CoA reductase (NADPH)] phosphate = phosphate + [hydroxymethylglutaryl-CoA reductase (NADPH)].	tmpzr1t_l9r_go_relaxed.owl	hydroxymethylglutaryl-CoA reductase (NADPH)-phosphatase activity|hydroxymethylglutaryl-CoA reductase (NADPH)-phosphate phosphohydrolase activity|reductase phosphatase activity				EC:3.1.3.47|MetaCyc:3.1.3.47-RXN									molecular_function											owl:Class	
GO:0046773	biolink:NamedThing	suppression by virus of host translation termination	Any viral process that stops, prevents, or reduces the frequency, rate or extent of translational termination of a host mRNA.	tmpzr1t_l9r_go_relaxed.owl	negative regulation by virus of host cell protein biosynthetic process shutoff|negative regulation by virus of host cell protein biosynthesis shutoff|viral inhibition of termination of host cell protein biosynthetic process|viral inhibition of host cell protein biosynthesis shutoff|viral suppression of termination by host of host cell protein biosynthetic process|viral suppression of termination by host of host cell protein biosynthesis|viral inhibition of termination of host cell protein biosynthesis|viral inhibition of host cell protein biosynthetic process shutoff|suppression by virus of host termination of protein biosynthetic process													biological_process											owl:Class	
GO:0000804	biolink:NamedThing	W chromosome	The sex chromosome present in females of species in which the female is the heterogametic sex; generally, the sex chromosome that pairs with the Z chromosome in the heterogametic sex. The W chromosome is absent from the cells of males and present in one copy in the somatic cells of females.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:ZW_sex-determination_system									cellular_component											owl:Class	
GO:0090415	biolink:NamedThing	7-hydroxymethyl chlorophyll a reductase activity	Catalysis of the reaction: 7-hydroxymethyl chlorophyll a + 2 reduced ferredoxin + 2 H+ chlorophyll a + 2 oxidized ferredoxin + H2O.	tmpzr1t_l9r_go_relaxed.owl								tb	2011-10-03T12:08:27Z					molecular_function											owl:Class	
GO:0019546	biolink:NamedThing	arginine deiminase pathway	The chemical reactions and pathways resulting in the breakdown of arginine into other compounds, including ornithine and CO2, using the enzyme arginine deiminase.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:ARGDEGRAD-PWY									biological_process											owl:Class	
GO:0003920	biolink:NamedThing	GMP reductase activity	Catalysis of the reaction: IMP + NADP(+) + NH(4)(+) = GMP + 2 H(+) + NADPH.	tmpzr1t_l9r_go_relaxed.owl	NADPH:guanosine-5'-phosphate oxidoreductase (deaminating) activity|inosine-5'-phosphate:NADP+ oxidoreductase (aminating)|guanosine 5'-monophosphate oxidoreductase activity|guanosine monophosphate reductase activity|NADPH:GMP oxidoreductase (deaminating) activity|guanosine 5'-monophosphate reductase activity|NADPH2:guanosine-5'-phosphate oxidoreductase (deaminating)|guanosine 5'-phosphate reductase activity|guanylate reductase activity				RHEA:17185|Reactome:R-HSA-514604|MetaCyc:GMP-REDUCT-RXN|EC:1.7.1.7|KEGG_REACTION:R01134	Note that this function was formerly EC:1.6.6.8.								molecular_function											owl:Class	
GO:0018738	biolink:NamedThing	S-formylglutathione hydrolase activity	Catalysis of the reaction: S-formylglutathione + H(2)O = formate + glutathione + H(+).	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0241|MetaCyc:S-FORMYLGLUTATHIONE-HYDROLASE-RXN|Reactome:R-HSA-5693724|KEGG_REACTION:R00527|RHEA:14961|EC:3.1.2.12									molecular_function											owl:Class	
GO:0075070	biolink:NamedThing	adhesion of symbiont hyphopodium to host	The attachment of a hyphopodium of the symbiont to its host via adhesion molecules. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	adhesion of symbiont hyphopodium to host during symbiotic interaction					Note that this term should not be used to annotate gene products of the host. It should only be used to annotate those gene products from the symbiont involved in this process.								biological_process											owl:Class	
GO:0075505	biolink:NamedThing	entry of intact viral capsid into host nucleus through nuclear pore complex	Viral penetration into the host nucleus where a viral capsid passes intact through the host nuclear pore complex (NPC).	tmpzr1t_l9r_go_relaxed.owl						This mechanism is used by viruses with capsids small enough to cross the nuclear pore complex, such as the single-stranded (ss) DNA viruses Parvoviridae, Circoviridae and Geminiviridae.		jl	2011-07-26T04:35:03Z					biological_process											owl:Class	
GO:0030151	biolink:NamedThing	molybdenum ion binding	Binding to a molybdenum ion (Mo).	tmpzr1t_l9r_go_relaxed.owl	molybdenum binding|Mo ion binding													molecular_function											owl:Class	
GO:0032422	biolink:NamedThing	purine-rich negative regulatory element binding	Binding to a 30-bp purine-rich negative regulatory element; the best characterized such element is found in the first intronic region of the rat cardiac alpha-myosin heavy chain gene, and contains two palindromic high-affinity Ets-binding sites (CTTCCCTGGAAG). The presence of this element restricts expression of the gene containing it to cardiac myocytes.	tmpzr1t_l9r_go_relaxed.owl	PNR element binding													molecular_function											owl:Class	
GO:0032458	biolink:NamedThing	slow endocytic recycling	The directed movement of membrane-bounded vesicles from deep (non-peripheral) compartments endocytic compartments back to the plasma membrane where they are recycled for further rounds of transport.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0051337	biolink:NamedThing	amitosis	Nuclear division that occurs by simple constriction of the nucleus without chromosome condensation or spindle formation.	tmpzr1t_l9r_go_relaxed.owl	Remak nuclear division|direct nuclear division													biological_process											owl:Class	
GO:2001094	biolink:NamedThing	xylotriose transport	The directed movement of a xylotrioseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl								jl	2011-09-21T02:03:26Z					biological_process											owl:Class	
GO:0050533	biolink:NamedThing	5-phytase activity	Catalysis of the reaction: H2O + myo-inositol hexakisphosphate = phosphate + 1L-myo-inositol 1,2,3,4,6-pentakisphosphate.	tmpzr1t_l9r_go_relaxed.owl	myo-inositol-hexakisphosphate 5-phosphohydrolase activity				MetaCyc:3.1.3.72-RXN|EC:3.1.3.72|RHEA:13001									molecular_function											owl:Class	
GO:0005944	biolink:NamedThing	phosphatidylinositol 3-kinase complex, class IB	A class I phosphatidylinositol 3-kinase complex that possesses 1-phosphatidylinositol-4-phosphate 3-kinase activity; comprises a catalytic class IB phosphoinositide 3-kinase (PI3K) subunit and an associated regulatory subunit that is larger than, and unrelated to, the p85 proteins present in class IA complexes. Class IB PI3Ks are stimulated by G-proteins and do not interact with the SH2-domain containing adaptors that bind to Class IA PI3Ks.	tmpzr1t_l9r_go_relaxed.owl	phosphoinositide 3-kinase complex, class IB|1-phosphatidylinositol-4-phosphate 3-kinase, class IB complex|1-phosphatidylinositol-4-phosphate kinase, class IB complex|class IB PI3K complex											GO:0035031		cellular_component											owl:Class	
GO:0050355	biolink:NamedThing	triphosphatase activity	Catalysis of the reaction: H(2)O + triphosphate = diphosphate + phosphate.	tmpzr1t_l9r_go_relaxed.owl	triphosphate phosphohydrolase activity|inorganic triphosphatase activity|tripolyphosphatase activity				RHEA:14157|MetaCyc:TRIPHOSPHATASE-RXN|KEGG_REACTION:R00138|EC:3.6.1.25									molecular_function											owl:Class	
GO:0070994	biolink:NamedThing	detection of oxidative stress	The series of events in which a stimulus indicating oxidative stress is received and converted into a molecular signal.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-10-30T02:54:35Z					biological_process											owl:Class	
GO:0102790	biolink:NamedThing	cyanidin 5,3-O-glycosyltransferase activity	Catalysis of the reaction: cyanidin 5-O-beta-D-glucoside + UDP-alpha-D-glucose = cyanin betaine + UDP.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-8006									molecular_function											owl:Class	
GO:0004513	biolink:NamedThing	neolactotetraosylceramide alpha-2,3-sialyltransferase activity	Catalysis of the reaction: CMP-N-acetylneuraminate + beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide = CMP + alpha-N-acetylneuraminyl-2,3-beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-D-glucosylceramide.	tmpzr1t_l9r_go_relaxed.owl	cytidine monophosphoacetylneuraminate-neolactotetraosylceramide sialyltransferase activity|sialyltransferase 3|SAT-3|CMP-N-acetylneuraminate:neolactotetraosylceramide alpha-2,3-sialyltransferase activity				RHEA:18913|EC:2.4.99.10|MetaCyc:2.4.99.10-RXN									molecular_function											owl:Class	
GO:0004066	biolink:NamedThing	asparagine synthase (glutamine-hydrolyzing) activity	Catalysis of the reaction: ATP + L-aspartate + L-glutamine = AMP + diphosphate + L-asparagine + L-glutamate.	tmpzr1t_l9r_go_relaxed.owl	asparagine synthetase B activity|glutamine-dependent asparagine synthetase activity|asparagine synthase (glutamine-hydrolysing)|AS|asparagine synthetase (glutamine-hydrolyzing) activity|AS-B activity|asparagine synthetase (glutamine-hydrolysing)|L-aspartate:L-glutamine amido-ligase (AMP-forming)				EC:6.3.5.4|Reactome:R-HSA-70599|MetaCyc:ASNSYNB-RXN|RHEA:12228									molecular_function											owl:Class	
GO:0009849	biolink:NamedThing	tryptophan-independent indoleacetic acid biosynthetic process	The chemical reactions and pathways resulting in the formation of indoleacetic acid, independent of tryptophan.	tmpzr1t_l9r_go_relaxed.owl	indoleacetic acid biosynthetic process, tryptophan-independent|tryptophan-independent indoleacetic acid formation|tryptophan-independent indoleacetic acid biosynthesis|tryptophan-independent indoleacetic acid anabolism|tryptophan-independent IAA biosynthetic process|tryptophan-independent indoleacetic acid synthesis|indoleacetic acid biosynthesis, tryptophan-independent				MetaCyc:PWY-581									biological_process											owl:Class	
GO:0103093	biolink:NamedThing	methylthioalkylmalate dehydrogenase activity	Catalysis of the reaction: 3-(7'-methylthio)heptylmalate <=> H+ + 2-oxo-10-methylthiodecanoate + carbon dioxide.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXNQT-4178									molecular_function											owl:Class	
GO:0015608	biolink:NamedThing	carbohydrate-importing ABC transporter activity	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + carbohydrate(out) -> ADP + phosphate + carbohydrate(in).	tmpzr1t_l9r_go_relaxed.owl	sugar transporter|carbohydrate uptake transporter activity|carbohydrate-importing ATPase activity	https://github.com/geneontology/go-ontology/issues/17289			TC:3.A.1.1.1									molecular_function											owl:Class	
GO:0034541	biolink:NamedThing	dimethylarsinite methyltransferase activity	Catalysis of the reaction: dimethylarsenous acid + R2S-CH3 = trimethylarsine oxide + R2SH.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0806									molecular_function											owl:Class	
GO:0050235	biolink:NamedThing	pyridoxal 4-dehydrogenase activity	Catalysis of the reaction: NAD(+) + pyridoxal = 4-pyridoxolactone + H(+) + NADH.	tmpzr1t_l9r_go_relaxed.owl	pyridoxal dehydrogenase activity|pyridoxal:NAD+ 4-oxidoreductase activity				EC:1.1.1.107|MetaCyc:PYRIDOXAL-4-DEHYDROGENASE-RXN|RHEA:21336|KEGG_REACTION:R01707									molecular_function											owl:Class	
GO:0102667	biolink:NamedThing	indole-3-acetyl-beta-1-D-glucose hydrolase activity	Catalysis of the reaction: 1-O-(indol-3-ylacetyl)-beta-D-glucose + H2O <=> H+ + indole-3-acetate + beta-D-glucose.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-3165									molecular_function											owl:Class	
GO:0071532	biolink:NamedThing	ankyrin repeat binding	Binding to an ankyrin repeat of a protein. Ankyrin repeats are tandemly repeated modules of about 33 amino acids; each repeat folds into a helix-loop-helix structure with a beta-hairpin/loop region projecting out from the helices at a 90-degree angle, and repeats stack to form an L-shaped structure.	tmpzr1t_l9r_go_relaxed.owl	ANK repeat binding							mah	2010-01-08T02:21:02Z					molecular_function											owl:Class	
GO:0030938	biolink:NamedThing	collagen type XVIII trimer	A collagen homotrimer of alpha1(XVIII) chains.	tmpzr1t_l9r_go_relaxed.owl														cellular_component											owl:Class	
GO:0110036	biolink:NamedThing	C2 domain binding	Binding to the C2 domain of a protein, a protein structural domain involved in targeting proteins to cell membranes.	tmpzr1t_l9r_go_relaxed.owl								kmv	2017-07-20T20:45:56Z					molecular_function											owl:Class	
GO:1901746	biolink:NamedThing	prephenate(2-) catabolic process	The chemical reactions and pathways resulting in the breakdown of prephenate(2-).	tmpzr1t_l9r_go_relaxed.owl	prephenate(2-) degradation|prephenate catabolism|prephenate(2-) breakdown|prephenate breakdown|prephenate(2-) catabolism|prephenate degradation							yaf	2013-01-14T10:13:53Z					biological_process											owl:Class	
GO:0032132	biolink:NamedThing	O6-alkylguanine-DNA binding	Binding to an O6-alkylguanine adduct in DNA.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0008111	biolink:NamedThing	alpha-methylacyl-CoA racemase activity	Catalysis of the reaction: (2S)-2-methylacyl-CoA = (2R)-2-methylacyl-CoA.	tmpzr1t_l9r_go_relaxed.owl	2-methylacyl-CoA 2-epimerase activity				Reactome:R-HSA-192056|EC:5.1.99.4|MetaCyc:5.1.99.4-RXN|RHEA:12657|Reactome:R-HSA-193736|Reactome:R-HSA-193452|Reactome:R-HSA-389897|Reactome:R-HSA-193763									molecular_function											owl:Class	
GO:1990390	biolink:NamedThing	protein K33-linked ubiquitination	A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 33 of the ubiquitin monomers, is added to a protein.	tmpzr1t_l9r_go_relaxed.owl								sp	2014-06-03T12:22:05Z					biological_process											owl:Class	
GO:0001051	biolink:NamedThing	plastid single-subunit type RNA polymerase binding	Binding to a single subunit plastid RNA polymerase enzyme, which is composed of a single catalytic subunit similar to the RNA polymerase enzymes from phages T3, T7, and SP6.	tmpzr1t_l9r_go_relaxed.owl								krc	2010-09-23T02:42:57Z					molecular_function											owl:Class	
GO:0017130	biolink:NamedThing	poly(C) RNA binding	Binding to a sequence of cytosine residues in an RNA molecule.	tmpzr1t_l9r_go_relaxed.owl	poly(rC) binding|poly(C) binding													molecular_function											owl:Class	
GO:0062050	biolink:NamedThing	GPI-mannose ethanolamine phosphate phosphodiesterase activity	A phosphoric diester hydrolase activity that removes the ethanolamine phosphate from mannose 2 of a GPI anchor.	tmpzr1t_l9r_go_relaxed.owl								dph	2018-06-01T18:26:54Z					molecular_function											owl:Class	
GO:0009877	biolink:NamedThing	nodulation	The formation of nitrogen-fixing root nodules on plant roots.	tmpzr1t_l9r_go_relaxed.owl	nodule formation|nodule development|nodule morphogenesis	https://github.com/geneontology/go-ontology/issues/20305										GO:0009878		biological_process											owl:Class	
GO:0102009	biolink:NamedThing	proline dipeptidase activity	Catalysis of the reaction: H2O + a dipeptide with proline at the C-terminal <=> L-proline + a standard alpha amino acid.	tmpzr1t_l9r_go_relaxed.owl					EC:3.4.13.9|MetaCyc:3.4.13.9-RXN									molecular_function											owl:Class	
GO:0070277	biolink:NamedThing	iodide oxidation	The chemical reactions and pathways by which iodide is converted to diiodine, with the concomitant loss of electrons.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0061694	biolink:NamedThing	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase complex	A catalytic protein complex that is capable of alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity.	tmpzr1t_l9r_go_relaxed.owl						An example of this complex is PhnI (P16687) in Escherichia coli.		dph	2015-05-06T10:12:02Z					cellular_component											owl:Class	
GO:0031847	biolink:NamedThing	type 1 neurotensin receptor binding	Binding to a type 1 neurotensin receptor.	tmpzr1t_l9r_go_relaxed.owl	type 1 neurotensin receptor ligand													molecular_function											owl:Class	
GO:0051764	biolink:NamedThing	actin crosslink formation	The process in which two or more actin filaments are connected together by proteins that act as crosslinks between the filaments. The crosslinked filaments may be on the same or differing axes.	tmpzr1t_l9r_go_relaxed.owl	actin bundling|actin crosslinking|formation of actin crosslink|bridging actin filaments					See also the molecular function term 'protein binding, bridging ; GO:0030674'.								biological_process											owl:Class	
GO:0071679	biolink:NamedThing	commissural neuron axon guidance	The process in which the migration of an axon growth cone of a commissural neuron is directed to its target in the brain in response to a combination of attractive and repulsive cues.	tmpzr1t_l9r_go_relaxed.owl	commissural neuron axon pathfinding							mah	2010-02-17T02:21:36Z					biological_process											owl:Class	
GO:0042609	biolink:NamedThing	CD4 receptor binding	Binding to a CD4, a receptor found on the surface of T cells, monocytes and macrophages.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0033738	biolink:NamedThing	methylenetetrahydrofolate reductase (ferredoxin) activity	Catalysis of the reaction: 5-methyltetrahydrofolate + oxidized ferredoxin = 5,10-methylenetetrahydrofolate + reduced ferredoxin.	tmpzr1t_l9r_go_relaxed.owl	5-methyltetrahydrofolate:ferredoxin oxidoreductase activity|5,10-methylenetetrahydrofolate reductase activity				RHEA:14229|MetaCyc:RXN-5061|EC:1.5.7.1									molecular_function											owl:Class	
GO:0008871	biolink:NamedThing	aminoglycoside 2''-nucleotidyltransferase activity	Catalysis of the reaction: nucleoside triphosphate + aminoglycoside = diphosphate + 2''-nucleotidylaminoglycoside.	tmpzr1t_l9r_go_relaxed.owl	2''-aminoglycoside nucleotidyltransferase activity|gentamicin 2''-nucleotidyltransferase activity|gentamicin 2''- adenylyltransferase activity|NTP:gentamicin 2''-nucleotidyltransferase activity|gentamycin 2''-nucleotidyltransferase activity				MetaCyc:2.7.7.46-RXN|EC:2.7.7.46									molecular_function											owl:Class	
GO:0047467	biolink:NamedThing	4-hydroxyphenylacetaldehyde-oxime isomerase activity	Catalysis of the reaction: (E)-4-hydroxyphenylacetaldehyde oxime = (Z)-4-hydroxyphenylacetaldehyde oxime.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0019716	biolink:NamedThing	N-terminal peptidyl-alanine monomethylation	The monomethylation of the N-terminal alanine of proteins to form the derivative peptidyl-N-methyl-L-alanine.	tmpzr1t_l9r_go_relaxed.owl					RESID:AA0061									biological_process											owl:Class	
GO:0052578	biolink:NamedThing	alpha-farnesene synthase activity	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = (E,E)-alpha-farnesene + diphosphate.	tmpzr1t_l9r_go_relaxed.owl	(E,E)-alpha-farnesene synthase activity				RHEA:27421|MetaCyc:RXN-8574			ai	2010-08-09T01:39:42Z					molecular_function											owl:Class	
GO:1901571	biolink:NamedThing	fatty acid derivative transport	The directed movement of a fatty acid derivative into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl								pr	2012-11-04T17:13:49Z					biological_process											owl:Class	
GO:0062069	biolink:NamedThing	GARP complex binding	Binding to a GARP complex.	tmpzr1t_l9r_go_relaxed.owl								dph	2018-08-31T14:11:17Z					molecular_function											owl:Class	
GO:0050334	biolink:NamedThing	thiaminase activity	Catalysis of the reaction: H(2)O + thiamine = 4-amino-5-hydroxymethyl-2-methylpyrimidine + 5-(2-hydroxyethyl)-4-methylthiazole + H(+).	tmpzr1t_l9r_go_relaxed.owl	thiaminase II activity				MetaCyc:THIAMINASE-RXN|EC:3.5.99.2|RHEA:17509|KEGG_REACTION:R02133									molecular_function											owl:Class	
GO:0008668	biolink:NamedThing	(2,3-dihydroxybenzoyl)adenylate synthase activity	Catalysis of the reaction: 2,3-dihydroxybenzoate + ATP = 2,3-dihydroxybenzoyl 5'-adenylate + diphosphate.	tmpzr1t_l9r_go_relaxed.owl	2,3-dihydroxybenzoate-AMP ligase activity|ATP:2,3-dihydroxybenzoate adenylyltransferase activity				EC:2.7.7.58|RHEA:20229|KEGG_REACTION:R01504|MetaCyc:DHBAMPLIG-RXN									molecular_function											owl:Class	
GO:2001290	biolink:NamedThing	hydroperoxide metabolic process	The chemical reactions and pathways involving a hydroperoxide.	tmpzr1t_l9r_go_relaxed.owl	hydroperoxide metabolism							pr	2012-02-09T03:35:37Z					biological_process											owl:Class	
GO:0061732	biolink:NamedThing	mitochondrial acetyl-CoA biosynthetic process from pyruvate	The chemical reactions and pathways resulting in the formation of acetyl-CoA from pyruvate in the mitochondrion. The process begins with the transport of pyruvate from the cytosol to the mitochondrion where it is subsequently decarboxylated to form acetyl-CoA.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-71397.1|Reactome:R-HSA-372342.1			dph	2015-08-24T13:44:02Z					biological_process											owl:Class	
GO:0035226	biolink:NamedThing	glutamate-cysteine ligase catalytic subunit binding	Binding to the catalytic subunit of glutamate-cysteine ligase.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0047165	biolink:NamedThing	flavonol-3-O-beta-glucoside O-malonyltransferase activity	Catalysis of the reaction: flavonol 3-O-beta-D-glucoside + malonyl-CoA = malonyl-flavonol 3-O-beta-D-glucoside + CoA.	tmpzr1t_l9r_go_relaxed.owl	malonyl-coenzyme A:flavonol-3-O-glucoside malonyltransferase activity|MAT-3|flavonol 3-O-glucoside malonyltransferase activity|malonyl-CoA:flavonol-3-O-beta-D-glucoside 6''-O-malonyltransferase activity				MetaCyc:2.3.1.116-RXN|RHEA:20085|EC:2.3.1.116									molecular_function											owl:Class	
GO:0047829	biolink:NamedThing	D-nopaline dehydrogenase activity	Catalysis of the reaction: N2-(D-1,3-dicarboxypropyl)-L-arginine + NADP+ + H2O = L-arginine + 2-oxoglutarate + NADPH.	tmpzr1t_l9r_go_relaxed.owl	D-nopaline synthase activity|N2-(D-1,3-dicarboxypropyl)-L-arginine:NADP+ oxidoreductase (L-arginine-forming)|2-N-(D-1,3-dicarboxypropyl)-L-arginine:NADP+ oxidoreductase (L-arginine-forming)|nopaline synthase activity|NOS activity|nopaline dehydrogenase activity				EC:1.5.1.19|RHEA:19637|MetaCyc:D-NOPALINE-DEHYDROGENASE-RXN									molecular_function											owl:Class	
GO:1902605	biolink:NamedThing	heterotrimeric G-protein complex assembly	The aggregation, arrangement and bonding together of a set of components to form a heterotrimeric G-protein complex.	tmpzr1t_l9r_go_relaxed.owl	heterotrimeric G-protein GTPase, alpha-subunit assembly|heterotrimeric G-protein GTPase, beta-subunit formation|heterotrimeric G-protein GTPase activity formation|heterotrimeric G-protein GTPase, beta-subunit assembly|heterotrimeric G-protein GTPase, gamma-subunit formation|heterotrimeric G-protein complex formation|heterotrimeric G-protein GTPase, alpha-subunit formation|heterotrimeric G-protein GTPase, gamma-subunit assembly|heterotrimeric G-protein GTPase activity assembly							dph	2013-12-30T16:31:28Z					biological_process											owl:Class	
GO:0010117	biolink:NamedThing	photoprotection	Protection mechanism used by plants under conditions of excess energy absorption as a consequence of the light reactions of photosynthesis.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0047360	biolink:NamedThing	undecaprenyl-phosphate galactose phosphotransferase activity	Catalysis of the reaction: all-trans-undecaprenyl phosphate + UDP-D-galactose = alpha-D-galactosyl-diphosphoundecaprenol + UMP.	tmpzr1t_l9r_go_relaxed.owl	undecaprenyl phosphate galactosyl-1-phosphate transferase activity|poly(isoprenol)-phosphate galactose phosphotransferase activity|poly(isoprenyl)phosphate galactosephosphatetransferase activity|UDP-galactose:undecaprenyl-phosphate galactose phosphotransferase activity|poly(isoprenol)-phosphate galactosephosphotransferase activity				MetaCyc:2.7.8.6-RXN|EC:2.7.8.6|RHEA:11652|KEGG_REACTION:R01535									molecular_function											owl:Class	
GO:0032018	biolink:NamedThing	2-methylbutanol:NADP oxidoreductase activity	Catalysis of the reaction: 2-methylbutanol + NADP+ = 2-methylbutanal + NADPH + H+.	tmpzr1t_l9r_go_relaxed.owl	2-methylbutanal reductase (NADP) activity|2-methylbutyraldehyde reductase (NADP) activity													molecular_function											owl:Class	
GO:0052788	biolink:NamedThing	d-4,5 unsaturated beta-glucuronyl hydrolase activity	Catalysis of the hydrolysis of the glycosidic bond in an unsaturated saccharide between the unsaturated glucuronyl residue at the nonreducing terminus and the saccharide linked to the residue.	tmpzr1t_l9r_go_relaxed.owl	unsaturated beta-glucuronyl hydrolase activity							ai	2011-10-04T12:59:37Z					molecular_function											owl:Class	
GO:0061568	biolink:NamedThing	GDP phosphorylation	The process of introducing a phosphate group into GDP, guanosine diphosphate, to produce GTP.	tmpzr1t_l9r_go_relaxed.owl								dph	2013-08-01T12:57:12Z					biological_process											owl:Class	
GO:0031581	biolink:NamedThing	hemidesmosome assembly	Assembly of hemidesmosomes, integrin-containing protein complexes that bind to laminin in the basal lamina. Hemidesmosomes form the contact between the basal surface of epithelial cells and the underlying basal lamina.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0050142	biolink:NamedThing	nitrogenase (flavodoxin) activity	Catalysis of the reaction: 6 reduced flavodoxin + 6 H+ + N2 + n ATP = 6 oxidized flavodoxin + 2 NH3 + n ADP + n phosphate.	tmpzr1t_l9r_go_relaxed.owl	reduced flavodoxin:dinitrogen oxidoreductase (ATP-hydrolysing)				EC:1.19.6.1|MetaCyc:NITROGENASE-FLAVODOXIN-RXN|RHEA:15645									molecular_function											owl:Class	
GO:0052580	biolink:NamedThing	(+)-pulegone reductase, (-)-menthone as substrate, activity	Catalysis of the reaction: (-)-menthone + NADP+ = (+)-pulegone + NADPH + H+.	tmpzr1t_l9r_go_relaxed.owl	(-)-menthone:NADP+ oxidoreductase activity				MetaCyc:RXN-5164|EC:1.3.1.81			ai	2010-08-09T04:33:53Z					molecular_function											owl:Class	
GO:0050622	biolink:NamedThing	glycine dehydrogenase (cyanide-forming) activity	Catalysis of the reaction: glycine + 2 A = HCN + CO2 + 2 AH2.	tmpzr1t_l9r_go_relaxed.owl	glycine:acceptor oxidoreductase (hydrogen-cyanide-forming)|hydrogen cyanide synthase activity|HCN synthase activity				EC:1.4.99.5|RHEA:15821|MetaCyc:1.4.99.5-RXN									molecular_function											owl:Class	
GO:0140459	biolink:NamedThing	response to Gram-positive bacterium	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a Gram-positive bacterium.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/19278						pg	2020-04-30T07:33:34Z					biological_process											owl:Class	
GO:1990525	biolink:NamedThing	BIR domain binding	Binding to a Baculovirus Inhibitor of apoptosis protein Repeat (BIR) domain.	tmpzr1t_l9r_go_relaxed.owl	Baculovirus Inhibitor of apoptosis protein Repeat domain binding					An example of this is the Drosophila reaper gene in PMID:21886178.		jl	2014-11-04T12:36:56Z					molecular_function											owl:Class	
GO:0071905	biolink:NamedThing	protein N-linked glucosylation via asparagine	A process of protein N-linked glycosylation via asparagine in which glucose is added to the N4 of asparagine, forming an (S)-2-amino-4-(D-glucopyranosyl)amino-4-oxobutanoic acid residue.	tmpzr1t_l9r_go_relaxed.owl	protein amino acid N-linked glucosylation via asparagine				RESID:AA0421			mah	2010-09-15T03:54:25Z					biological_process											owl:Class	
GO:0031804	biolink:NamedThing	type 7 metabotropic glutamate receptor binding	Binding to a type 7 metabotropic glutamate receptor.	tmpzr1t_l9r_go_relaxed.owl	type 7 metabotropic glutamate receptor ligand													molecular_function											owl:Class	
GO:0050034	biolink:NamedThing	L-rhamnose 1-dehydrogenase activity	Catalysis of the reaction: L-rhamnofuranose + NAD(+) = L-rhamnono-1,4-lactone + H(+) + NADH.	tmpzr1t_l9r_go_relaxed.owl	L-rhamnofuranose:NAD+ 1-oxidoreductase activity				MetaCyc:L-RHAMNOSE-1-DEHYDROGENASE-RXN|KEGG_REACTION:R03942|EC:1.1.1.173|RHEA:12649									molecular_function											owl:Class	
GO:0034691	biolink:NamedThing	integrin alphaE-beta7 complex	An integrin complex that comprises one alphaE subunit and one beta7 subunit.	tmpzr1t_l9r_go_relaxed.owl	Itgae-Itgb7 complex													cellular_component											owl:Class	
GO:0010249	biolink:NamedThing	auxin conjugate metabolic process	The chemical reactions and pathways involving auxin conjugates, a bound form of auxin.	tmpzr1t_l9r_go_relaxed.owl	auxin conjugate metabolism													biological_process											owl:Class	
GO:0004617	biolink:NamedThing	phosphoglycerate dehydrogenase activity	Catalysis of the reaction: 3-phosphoglycerate + NAD+ = 3-phosphohydroxypyruvate + NADH + H+.	tmpzr1t_l9r_go_relaxed.owl	D- and L-HGA|SerA 3PG dehydrogenase activity|3-phosphoglycerate:NAD+ 2-oxidoreductase activity|D-3-phosphoglycerate dehydrogenase activity|3-phospho-D-glycerate:NAD+ 2-oxidoreductase activity|SerA|phosphoglycerate oxidoreductase activity|alpha-phosphoglycerate dehydrogenase activity|3-phosphoglyceric acid dehydrogenase activity|alpha-KG reductase activity|D-3-phosphoglycerate:NAD+ oxidoreductase activity|alphaKG reductase activity|3PHP reductase activity|phosphoglyceric acid dehydrogenase activity|3-phosphoglycerate dehydrogenase activity|glycerate-1,3-phosphate dehydrogenase activity|glycerate 3-phosphate dehydrogenase activity|PGDH activity				MetaCyc:PGLYCDEHYDROG-RXN|RHEA:12641|EC:1.1.1.95|Reactome:R-HSA-977348									molecular_function											owl:Class	
GO:0050084	biolink:NamedThing	mannitol-1-phosphatase activity	Catalysis of the reaction: D-mannitol 1-phosphate + H(2)O = D-mannitol + 2 H(+) + phosphate.	tmpzr1t_l9r_go_relaxed.owl	D-mannitol-1-phosphate phosphohydrolase activity|mannitol-1-phosphate phosphatase activity				EC:3.1.3.22|MetaCyc:MANNITOL-1-PHOSPHATASE-RXN|RHEA:19537|KEGG_REACTION:R02167									molecular_function											owl:Class	
GO:0034353	biolink:NamedThing	RNA pyrophosphohydrolase activity	Catalysis of the removal of a 5' terminal pyrophosphate from the 5'-triphosphate end of an RNA, leaving a 5'-monophosphate end.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0004487	biolink:NamedThing	methylenetetrahydrofolate dehydrogenase (NAD+) activity	Catalysis of the reaction: 5,10-methylenetetrahydrofolate + NAD(+) = 5,10-methenyltetrahydrofolate + NADH.	tmpzr1t_l9r_go_relaxed.owl	5,10-methylenetetrahydrofolate:NAD+ oxidoreductase|5,10-methylenetetrahydrofolate dehydrogenase activity				Reactome:R-HSA-6801462|MetaCyc:1.5.1.15-RXN|EC:1.5.1.15|RHEA:22892|KEGG_REACTION:R01218									molecular_function											owl:Class	
GO:0140417	biolink:NamedThing	ATP-sensitive calcium-release channel activity	Enables the transmembrane transfer of a calcium ion from intracellular stores by a channel that opens when a ATP has been bound by the channel complex or one of its constituent parts.	tmpzr1t_l9r_go_relaxed.owl								pg	2020-01-27T09:22:04Z					molecular_function											owl:Class	
GO:0034550	biolink:NamedThing	dimethylarsinate reductase activity	Catalysis of the reaction: dimethylarsinate + 3 H+ + 2 e- = dimethylarsinous acid + H2O.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0838|EC:1.97.1.-									molecular_function											owl:Class	
GO:0071253	biolink:NamedThing	connexin binding	Binding to a connexin, any of a group of related proteins that assemble to form gap junctions.	tmpzr1t_l9r_go_relaxed.owl								mah	2009-12-04T10:07:54Z					molecular_function											owl:Class	
GO:0048785	biolink:NamedThing	hatching gland development	The process whose specific outcome is the progression of the hatching gland over time, from its formation to the mature structure. The cells of the hatching gland contain enzymes responsible for solubilization of the egg chorion, facilitating the hatching process.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0018795	biolink:NamedThing	2-hydroxy-2-methyl-1,3-dicarbonate decarboxylase activity	Catalysis of the reaction: 2-hydroxy-2-methyl-1,3-dicarbonate + H+ = CO2 + L-lactate.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0621									molecular_function											owl:Class	
GO:0033107	biolink:NamedThing	Cvt vesicle	A cytosolic vesicle that is enclosed by a double membrane and is implicated in the cytoplasm to vacuole targeting pathway. These vesicles are found in the yeast S. cerevisiae, and contain vacuolar hydrolases, aminopeptidase I (Ape1p) and alpha-mannosidase (Ams1p).	tmpzr1t_l9r_go_relaxed.owl	cytoplasm-to-vacuole targeting vesicle|cytoplasm to vacuole targeting vesicle													cellular_component											owl:Class	
GO:0102742	biolink:NamedThing	R(+)-3,4-dihydroxyphenyllactate:NADP+ oxidoreductase activity	Catalysis of the reaction: H+ + 3,4-dihydroxyphenylpyruvate + NADPH <=> (2R)-3-(3,4-dihydroxyphenyl)lactate + NADP.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-7632|EC:1.1.1.237									molecular_function											owl:Class	
GO:0044387	biolink:NamedThing	negative regulation of protein kinase activity by regulation of protein phosphorylation	The stopping, prevention, or reduction in frequency, rate or extent of protein kinase activity as a result of regulating the phosphorylation status of that protein kinase.	tmpzr1t_l9r_go_relaxed.owl								jl	2011-12-13T04:49:36Z					biological_process											owl:Class	
GO:0047969	biolink:NamedThing	glyoxylate oxidase activity	Catalysis of the reaction: glyoxylate + H(2)O + O(2) = H(2)O(2) + H(+) + oxalate.	tmpzr1t_l9r_go_relaxed.owl	glyoxylate:oxygen oxidoreductase activity				RHEA:14837|MetaCyc:GLYOXYLATE-OXIDASE-RXN|KEGG_REACTION:R00466|EC:1.2.3.5|Reactome:R-HSA-389862									molecular_function											owl:Class	
GO:0036033	biolink:NamedThing	mediator complex binding	Binding to a mediator complex. The mediator complex is a protein complex that interacts with the carboxy-terminal domain of the largest subunit of RNA polymerase II and plays an active role in transducing the signal from a transcription factor to the transcriptional machinery. The Saccharomyces complex contains several identifiable subcomplexes: a head domain comprising Srb2, -4, and -5, Med6, -8, and -11, and Rox3 proteins; a middle domain comprising Med1, -4, and -7, Nut1 and -2, Cse2, Rgr1, Soh1, and Srb7 proteins; a tail consisting of Gal11p, Med2p, Pgd1p, and Sin4p; and a regulatory subcomplex comprising Ssn2, -3, and -8, and Srb8 proteins. Metazoan mediator complexes have similar modular structures and include homologs of yeast Srb and Med proteins.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-10-31T05:09:12Z					molecular_function											owl:Class	
GO:1990879	biolink:NamedThing	CST complex	A complex formed by the association of Cdc13 (CTC1 in mammals) with Stn1 in yeast (OBFC1 in mammals) and Ten1 protein (also TEN1 in mammals) with single-stranded telomeric DNA. The CST complex plays a role in telomere protection.	tmpzr1t_l9r_go_relaxed.owl	Cdc13-Stn1-Ten1 complex|CTC1-OBFC1-TEN1 complex							nc	2015-10-20T13:51:07Z					cellular_component											owl:Class	
GO:0006881	biolink:NamedThing	extracellular sequestering of iron ion	The process of binding or confining iron ions in an extracellular area such that they are separated from other components of a biological system.	tmpzr1t_l9r_go_relaxed.owl	extracellular iron ion retention|extracellular iron ion sequestering|extracellular storage of iron ion|extracellular iron ion sequestration|extracellular iron ion storage|extracellular retention of iron ion|extracellular sequestration of iron ion													biological_process											owl:Class	
GO:0140284	biolink:NamedThing	endoplasmic reticulum-endosome membrane contact site	A contact site between the endoplasmic reticulum membrane and the endosome membrane.	tmpzr1t_l9r_go_relaxed.owl	ER-endosome membrane contact site							pg	2018-10-30T10:29:28Z					cellular_component											owl:Class	
GO:0033995	biolink:NamedThing	anhydrosialidase activity	Catalysis of the reaction: an N-acetylneuraminate glycoside = 2,7-anhydro-alpha-N-acetylneuraminate + an alpha-sialyl group. This reaction is the elimination of alpha-sialyl groups in N-acetylneuraminic acid glycosides, releasing 2,7-anhydro-alpha-N-acetylneuraminate.	tmpzr1t_l9r_go_relaxed.owl	sialidase L activity|sialglycoconjugate N-acylneuraminylhydrolase (2,7-cyclizing) activity|glycoconjugate sialyl-lyase (2,7-cyclizing) activity|anhydroneuraminidase activity				EC:4.2.2.15|MetaCyc:4.2.2.15-RXN									molecular_function											owl:Class	
GO:0097408	biolink:NamedThing	fibrillary inclusion	Cellular inclusion consisting of circular areas filled with fine slender filaments about 10 nanometers in diameter, delimited by a wall of varying complexity (either a single continuous membrane or a tubular network consisting of a fine filamentous material giving the wall a honeycomb appearance). Fibrillary inclusions are found in the cytoplasm of giant cells of Dieters in the lateral vestibular nucleus of the rat; similar structures have been described in the ventral cochlear nucleus, spinal cord, and substantia nigra.	tmpzr1t_l9r_go_relaxed.owl					NIF_Subcellular:sao967812059			pr	2012-10-31T13:53:58Z					cellular_component											owl:Class	
GO:0047222	biolink:NamedThing	mannotetraose 2-alpha-N-acetylglucosaminyltransferase activity	Catalysis of the reaction: 1,3-alpha-D-mannosyl-1,2-alpha-D-mannosyl-1,2-alpha-D-mannosyl-D-mannose + UDP-N-acetyl-D-glucosamine = 1,3-alpha-D-mannosyl-1,2-(N-acetyl-alpha-D-glucosaminyl-alpha-D-mannosyl)-1,2-alpha-D-mannosyl-D-mannose + UDP.	tmpzr1t_l9r_go_relaxed.owl	alpha-N-acetylglucosaminyltransferase activity|UDP-N-acetyl-D-glucosamine:mannotetraose alpha-N-acetyl-D-glucosaminyltransferase activity|uridine diphosphoacetylglucosamine mannoside alpha1->2-alphacetylglucosaminyltransferase activity				EC:2.4.1.138|MetaCyc:2.4.1.138-RXN|RHEA:13705									molecular_function											owl:Class	
GO:0008957	biolink:NamedThing	phenylacetaldehyde dehydrogenase activity	Catalysis of the reaction: phenylacetaldehyde + NAD+ + H2O = phenylacetate + NADH + H+.	tmpzr1t_l9r_go_relaxed.owl	phenylacetaldehyde:NAD+ oxidoreductase activity				UM-BBD_reactionID:r0035|EC:1.2.1.39|MetaCyc:PHENDEHYD-RXN|RHEA:21392									molecular_function											owl:Class	
GO:0050221	biolink:NamedThing	prostaglandin-E2 9-reductase activity	Catalysis of the reaction: (5Z,13E)-(15S)-9-alpha,11-alpha,15-trihydroxyprosta-5,13-dienoate + NADP+ = (5Z,13E)-(15S)-11-alpha,15-dihydroxy-9-oxoprosta-5,13-dienoate + NADPH.	tmpzr1t_l9r_go_relaxed.owl	PGE2-9-ketoreductase activity|prostaglandin E2-9-oxoreductase activity|prostaglandin-E(2) 9-oxoreductase activity|9-keto-prostaglandin E(2) reductase activity|9-ketoprostaglandin reductase activity|PGE2 9-ketoreductase activity|PGE(2) 9-oxoreductase activity|(5Z,13E)-(15S)-9alpha,11alpha,15-trihydroxyprosta-5,13-dienoate:NADP+ 9-oxidoreductase activity|PGE2-9-OR|prostaglandin E 9-ketoreductase activity|prostaglandin-E2 9-oxoreductase activity|9-keto-prostaglandin E2 reductase activity|PGE(2) 9-ketoreductase activity|PGE2 9-oxoreductase activity|reductase, 15-hydroxy-9-oxoprostaglandin|PGE-9-ketoreductase activity				RHEA:24508|Reactome:R-HSA-2161651|EC:1.1.1.189|MetaCyc:PROSTAGLANDIN-E2-9-REDUCTASE-RXN									molecular_function											owl:Class	
GO:0036351	biolink:NamedThing	histone H2A-K13 ubiquitination	The modification of histone H2A by addition of ubiquitin group at lysine 13 (H2A-K13) in metazoans, and at the equivalent residue in other organisms. Monoubiquitin is first attached to H2A-K13 and K63-linked ubiquitin chains are then extended from this monoubiquitin.	tmpzr1t_l9r_go_relaxed.owl	histone H2A ubiquitination (H2A-K13)							bf	2012-09-19T11:48:05Z					biological_process											owl:Class	
GO:0039717	biolink:NamedThing	spherule viral factory	A cytoplasmic viral factory which is a 50-400nm diameter membrane invagination. Spherules can appear on several enveloped cellular components depending on the virus.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Viroplasm			bf	2013-12-19T15:25:57Z					cellular_component											owl:Class	
GO:0102765	biolink:NamedThing	UDP-D-apiose synthase activity	Catalysis of the reaction: H+ + UDP-alpha-D-glucuronate = UDP-alpha-D-apiose + carbon dioxide.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-7770									molecular_function											owl:Class	
GO:0072590	biolink:NamedThing	N-acetyl-L-aspartate-L-glutamate ligase activity	Catalysis of the reaction: ATP + N-acetyl-L-aspartate + L-glutamate = ADP + phosphate + N-acetylaspartyl-glutamate.	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-8942575			mah	2011-02-10T03:20:41Z					molecular_function											owl:Class	
GO:0106282	biolink:NamedThing	isoursodeoxycholate 7-beta-dehydrogenase (NAD+) activity	Catalysis of the reaction: 3beta,7beta-dihydroxy-5beta-cholan-24-oate + NAD(+) = 3beta-hydroxy-7-oxo-5beta-cholan-24-oate + H(+) + NADH.	tmpzr1t_l9r_go_relaxed.owl					RHEA:42024			hjd	2020-07-29T17:51:00Z					molecular_function											owl:Class	
GO:0021976	biolink:NamedThing	medulla reticulospinal tract morphogenesis	Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the medulla towards target cells in the spinal cord.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0021824	biolink:NamedThing	cerebral cortex tangential migration using cell-axon interactions	The movement of cerebral cortex neuronal precursors tangentially through the cortex using interaction of the migrating cells with axons of other neurons.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0097150	biolink:NamedThing	neuronal stem cell population maintenance	Any process in by an organism or tissue maintains a population of neuronal stem cells.	tmpzr1t_l9r_go_relaxed.owl								pr	2011-08-04T11:18:28Z					biological_process											owl:Class	
GO:0032447	biolink:NamedThing	protein urmylation	Covalent attachment of the ubiquitin-like protein URM1 to another protein.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:1990424	biolink:NamedThing	protein arginine kinase activity	Catalysis of the reaction: ATP + a protein arginine = ADP + protein arginine phosphate.	tmpzr1t_l9r_go_relaxed.owl						This reaction occurs in bacterial species e.g. Bacillus subtilis.		jl	2014-07-23T13:35:56Z					molecular_function											owl:Class	
GO:0102521	biolink:NamedThing	tRNA-4-demethylwyosine synthase activity	Catalysis of the reaction: pyruvate + S-adenosyl-L-methionine  + N1-methylguanine37 in tRNAPhe = L-methionine  + 5'-deoxyadenosine + carbon dioxide + H2O + 4-demethylwyosine37 in tRNAPhe.	tmpzr1t_l9r_go_relaxed.owl					EC:4.1.3.44|RHEA:36347|MetaCyc:RXN-14516									molecular_function											owl:Class	
GO:0080133	biolink:NamedThing	midchain alkane hydroxylase activity	Catalysis of the conversion of an alkane to a secondary alcohol.	tmpzr1t_l9r_go_relaxed.owl								dhl	2009-05-06T04:46:17Z					molecular_function											owl:Class	
GO:0034280	biolink:NamedThing	ent-sandaracopimaradiene synthase activity	Catalysis of the reaction: ent-copalyl diphosphate = ent-sandaracopimara-8(14),15-diene + diphosphate.	tmpzr1t_l9r_go_relaxed.owl	ent-copalyl-diphosphate diphosphate-lyase [ent-sandaracopimara-8(14),15-diene-forming] activity|ent-pimaradiene synthase activity				MetaCyc:RXN-4884|RHEA:25536|KEGG_REACTION:R09120|EC:4.2.3.29									molecular_function											owl:Class	
GO:0015752	biolink:NamedThing	D-ribose transmembrane transport	The process in which D-ribose is transported across a lipid bilayer, from one side of a membrane to the other. As beta-D-ribofuranose, D-ribose forms the glycose group of all ribonucleosides, ribonucleotides and ribonucleic acids, and also of ribose phosphates, various glycosides, some coenzymes and some forms of vitamin B12.	tmpzr1t_l9r_go_relaxed.owl	D-ribose transport													biological_process											owl:Class	
GO:0019701	biolink:NamedThing	peptidyl-arginine N5-methylation	The methylation of peptidyl-arginine on the internal nitrogen-5 (N5) atom (also called delta-nitrogen) to form peptidyl-N5-methyl-L-arginine.	tmpzr1t_l9r_go_relaxed.owl	peptidyl-arginine delta-N-methylation				RESID:AA0305									biological_process											owl:Class	
GO:0018638	biolink:NamedThing	toluene 4-monooxygenase activity	Catalysis of the reaction: toluene + 1/2 O2 = 4-hydroxytoluene.	tmpzr1t_l9r_go_relaxed.owl					EC:1.14.13.-|UM-BBD_enzymeID:e0225									molecular_function											owl:Class	
GO:0031385	biolink:NamedThing	regulation of termination of mating projection growth	Any process that modulates the frequency, rate, or extent of the end of mating projection formation by unicellular fungi.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0050733	biolink:NamedThing	RS domain binding	Binding to an RS domain of a protein; RS domains are usually highly phosphorylated and characterized by the presence of arginine (R)/serine (S) dipeptides. The RS domain promotes protein-protein interactions and directs subcellular localization and, in certain situations, nucleocytoplasmic shuttling of individual SR proteins. They also play a role in splicing.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0097241	biolink:NamedThing	hematopoietic stem cell migration to bone marrow	The orderly movement of a hematopoietic stem cell into the bone marrow, and its subsequent positioning within defined functional compartments in that microenvironment. A hematopoietic stem cell is a cell from which all cells of the lymphoid and myeloid lineages develop, including blood cells and cells of the immune system.	tmpzr1t_l9r_go_relaxed.owl	hematopoietic stem cell homing|hemopoietic stem cell migration to bone marrow|progenitor cell homing							pr	2012-02-09T01:08:32Z					biological_process											owl:Class	
GO:0047447	biolink:NamedThing	erythro-3-hydroxyaspartate ammonia-lyase activity	Catalysis of the reaction: erythro-3-hydroxy-L-aspartate = NH3 + oxaloacetic acid.	tmpzr1t_l9r_go_relaxed.owl	erythro-3-hydroxy-Ls-aspartate hydro-lyase (deaminating)|erythro-3-hydroxy-Ls-aspartate ammonia-lyase (oxaloacetate-forming)|erythro-3-hydroxy-Ls-aspartate ammonia-lyase activity|erythro-3-hydroxy-L(s)-aspartate hydro-lyase (deaminating) activity|erythro-beta-hydroxyaspartate dehydratase activity|3-hydroxyaspartate dehydratase activity|erythro-3-hydroxyaspartate dehydratase activity				MetaCyc:4.3.1.20-RXN|EC:4.3.1.20|RHEA:19757									molecular_function											owl:Class	
GO:0016618	biolink:NamedThing	hydroxypyruvate reductase activity	Catalysis of the reaction: D-glycerate + NADP+ = hydroxypyruvate + NADPH + H+.	tmpzr1t_l9r_go_relaxed.owl	beta-hydroxypyruvate reductase activity|NADH:hydroxypyruvate reductase activity|D-glycerate:NADP+ 2-oxidoreductase activity|D-glycerate dehydrogenase activity				RHEA:18657|EC:1.1.1.81|MetaCyc:RXN0-300|MetaCyc:HYDROXYPYRUVATE-REDUCTASE-RXN									molecular_function											owl:Class	
GO:0102582	biolink:NamedThing	cyanidin 3-O-p-coumaroylglucoside 2-O''-xylosyltransferase activity	Catalysis of the reaction: cyanidin 3-O-(6-O-(E)-4-coumaroyl-beta-D-glucoside) + UDP-alpha-D-xylose <=> cyanidin 3-O-[2''-O-xylosyl) 6''-O-(p-coumaroyl) glucoside + UDP + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-15328									molecular_function											owl:Class	
GO:0048540	biolink:NamedThing	bursa of Fabricius development	The process whose specific outcome is the progression of the bursa of Fabricius over time, from its formation to the mature structure. The bursa of Fabricius is an organ found in birds involved in B cell differentiation.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0051212	biolink:NamedThing	vanadium ion binding	Binding to a vanadium ion (V).	tmpzr1t_l9r_go_relaxed.owl	V ion binding													molecular_function											owl:Class	
GO:0045326	biolink:NamedThing	protein-DNA covalent cross-linking via the 3'-end to peptidyl-tyrosine	The formation of a covalent cross-link between DNA and a peptidyl-tyrosine residue by the formation of O4'-(phospho-3'-DNA)-L-tyrosine.	tmpzr1t_l9r_go_relaxed.owl	DNA-protein covalent cross-linking via the 3'-end to peptidyl-tyrosine				RESID:AA0323									biological_process											owl:Class	
GO:0044314	biolink:NamedThing	protein K27-linked ubiquitination	A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 27 of the ubiquitin monomers, is added to a protein.	tmpzr1t_l9r_go_relaxed.owl	protein K27-linked polyubiquitination							jl	2010-06-02T11:48:08Z					biological_process											owl:Class	
GO:0047086	biolink:NamedThing	ketosteroid monooxygenase activity	Catalysis of the reaction: O2 + NADPH + progesterone = H2O + NADP+ + testosterone acetate.	tmpzr1t_l9r_go_relaxed.owl	steroid-ketone monooxygenase activity|ketosteroid,NADPH:oxygen oxidoreductase (20-hydroxylating, ester-producing/20-hydroxylating, side-chain cleaving/17-hydroxylating, lactonizing)|progesterone, NADPH2:oxygen oxidoreductase (20-hydroxylating, ester-producing)|17alpha-hydroxyprogesterone, NADPH2:oxygen oxidoreductase (20-hydroxylating, side-chain cleaving)|androstenedione, NADPH2:oxygen oxidoreductase (17-hydroxylating, lactonizing)				MetaCyc:1.14.13.54-RXN|EC:1.14.13.54									molecular_function											owl:Class	
GO:0009922	biolink:NamedThing	fatty acid elongase activity	Catalysis of the reaction: fatty acid (C-16 or longer) + 2-C = fatty acid (C-16 or longer + 2-C).	tmpzr1t_l9r_go_relaxed.owl					Reactome:R-HSA-2046094|Reactome:R-HSA-2046083|MetaCyc:ICOSANOYL-COA-SYNTHASE-RXN|Reactome:R-HSA-2046100|Reactome:R-HSA-548830|Reactome:R-HSA-2046088|Reactome:R-HSA-548815|Reactome:R-HSA-2046095|Reactome:R-HSA-548800|Reactome:R-HSA-548814|Reactome:R-HSA-2046090									molecular_function											owl:Class	
GO:0047236	biolink:NamedThing	methyl-ONN-azoxymethanol beta-D-glucosyltransferase activity	Catalysis of the reaction: methylazoxymethanol + UDP-D-glucose = H+ + cycasin + UDP.	tmpzr1t_l9r_go_relaxed.owl	methyl-ONN-azoxymethanol glucosyltransferase activity|uridine diphosphoglucose-methylazoxymethanol glucosyltransferase activity|UDPglucose-methylazoxymethanol glucosyltransferase activity|UDP-glucose:methyl-ONN-azoxymethanol beta-D-glucosyltransferase activity|cycasin synthase activity				MetaCyc:2.4.1.171-RXN|RHEA:20205|EC:2.4.1.171									molecular_function											owl:Class	
GO:1990946	biolink:NamedThing	meiosis I/meiosis II transition	The cell cycle process in which a cell progresses from meiosis I to meiosis II.	tmpzr1t_l9r_go_relaxed.owl								vw	2016-04-21T13:01:07Z					biological_process											owl:Class	
GO:0005536	biolink:NamedThing	glucose binding	Binding to D- or L-enantiomers of glucose.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0019162	biolink:NamedThing	pyridoxamine-oxaloacetate transaminase activity	Catalysis of the reaction: oxaloacetate + pyridoxamine = L-aspartate + pyridoxal.	tmpzr1t_l9r_go_relaxed.owl	pyridoxamine--oxaloacetate aminotransferase activity|pyridoxamine:oxaloacetate aminotransferase activity|pyridoxamine-oxaloacetate aminotransferase activity				RHEA:10844|EC:2.6.1.31|MetaCyc:PYROXALTRANSAM-RXN|KEGG_REACTION:R01713									molecular_function											owl:Class	
GO:0030982	biolink:NamedThing	adventurous gliding motility	A process involved in the controlled movement of a bacterial cell powered by the rearward secretion of carbohydrate slime.	tmpzr1t_l9r_go_relaxed.owl	adventurous gliding movement													biological_process											owl:Class	
GO:0030338	biolink:NamedThing	CMP-N-acetylneuraminate monooxygenase activity	Catalysis of the reaction: CMP-N-acetylneuraminate + NADPH + H+ + O2 = CMP-N-glycoloylneuraminate + NADP+ + H2O.	tmpzr1t_l9r_go_relaxed.owl	CMP-N-acetylneuraminic acid hydroxylase activity|CMP-Neu5Ac hydroxylase activity|CMP-N-acetylneuraminate hydroxylase activity|CMP-N-acetylneuraminate,ferrocytochrome-b5:oxygen oxidoreductase (N-acetyl-hydroxylating)|cytidine monophosphoacetylneuraminate monooxygenase activity|cytidine-5'-monophosphate-N-acetylneuraminic acid hydroxylase activity|N-acetylneuraminic monooxygenase activity				MetaCyc:1.14.13.45-RXN|RHEA:16145|EC:1.14.18.2	Note that this was EC:1.14.13.45.								molecular_function											owl:Class	
GO:0050438	biolink:NamedThing	2-ethylmalate synthase activity	Catalysis of the reaction: 2-oxobutanate + acetyl-CoA + H(2)O = (R)-2-ethylmalate + CoA + H(+).	tmpzr1t_l9r_go_relaxed.owl	acetyl-CoA:2-oxobutanoate C-acetyltransferase (thioester-hydrolysing, carboxymethyl-forming)|propylmalic synthase activity|propylmalate synthase activity|2-ethylmalate-3-hydroxybutanedioate synthase activity|(R)-2-ethylmalate 2-oxobutanoyl-lyase (CoA-acetylating) activity				KEGG_REACTION:R00998|EC:2.3.3.6|MetaCyc:2-ETHYLMALATE-SYNTHASE-RXN|RHEA:23040									molecular_function											owl:Class	
GO:0050202	biolink:NamedThing	octopamine dehydratase activity	Catalysis of the reaction: 1-(4-hydroxyphenyl)-2-aminoethanol = (4-hydroxyphenyl)acetaldehyde + NH(4)(+).	tmpzr1t_l9r_go_relaxed.owl	octopamine hydro-lyase (deaminating)|octopamine hydro-lyase [deaminating; (4-hydroxyphenyl)acetaldehyde-forming]|octopamine hydrolyase activity				KEGG_REACTION:R03358|MetaCyc:OCTOPAMINE-DEHYDRATASE-RXN|RHEA:18173|EC:4.2.1.87									molecular_function											owl:Class	
GO:0003879	biolink:NamedThing	ATP phosphoribosyltransferase activity	Catalysis of the reaction: 1-(5-phospho-D-ribosyl)-ATP + diphosphate = ATP + 5-phospho-alpha-D-ribose 1-diphosphate.	tmpzr1t_l9r_go_relaxed.owl	1-(5-phospho-D-ribosyl)-ATP:diphosphate phospho-alpha-D-ribosyl-transferase activity|phosphoribosyladenosine triphosphate:pyrophosphate phosphoribosyltransferase activity|phosphoribosyl-ATP diphosphorylase activity|phosphoribosyladenosine triphosphate pyrophosphorylase activity|adenosine triphosphate phosphoribosyltransferase activity|phosphoribosyl-ATP pyrophosphorylase activity|phosphoribosyl ATP:pyrophosphate phosphoribosyltransferase activity|phosphoribosyl-ATP:pyrophosphate-phosphoribosyl phosphotransferase activity|phosphoribosyl ATP synthetase activity|phosphoribosyladenosine triphosphate synthetase activity				RHEA:18473|MetaCyc:ATPPHOSPHORIBOSYLTRANS-RXN|EC:2.4.2.17									molecular_function											owl:Class	
GO:0010401	biolink:NamedThing	pectic galactan metabolic process	The chemical reactions and pathways involving galactan, a polymer of D-galactosyl units that can be found as a side chain of the pectin rhamnogalacturonan I.	tmpzr1t_l9r_go_relaxed.owl	pectic galactan metabolism													biological_process											owl:Class	
GO:0010019	biolink:NamedThing	chloroplast-nucleus signaling pathway	The process in which a molecular signal is transduced between the chloroplast and nucleus, such that expression of nuclear encoding photosynthetic proteins is coupled with chloroplast biogenesis.	tmpzr1t_l9r_go_relaxed.owl	chloroplast-nucleus signalling pathway													biological_process											owl:Class	
GO:0015039	biolink:NamedThing	NADPH-adrenodoxin reductase activity	Catalysis of the reaction: oxidized adrenodoxin + NADPH + H+ = reduced adrenodoxin + NADP+.	tmpzr1t_l9r_go_relaxed.owl	adrenodoxin-type ferredoxin reductase activity|adrenodoxin reductase activity|NADPH:adrenodoxin oxidoreductase activity				EC:1.18.1.6|RHEA:42312|MetaCyc:RXN-13685	Note that this term specifically refers to the reaction proceeding in the direction shown; under physiological conditions adrenodoxin reduction by adrenodoxin reductase is coupled with electron transfer from AdR to P450, which catalyzes an irreversible monooxygenation reaction. This term should therefore be used to annotate gene products that catalyze the reduction of oxidized adrenodoxin; also consider annotating to the molecular function term 'ferredoxin-NADP+ reductase activity ; GO:0004324'.								molecular_function											owl:Class	
GO:0070383	biolink:NamedThing	DNA cytosine deamination	The removal of an amino group from a cytosine residue in DNA, forming a uracil residue.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0075502	biolink:NamedThing	endosome membrane permeabilization involved in viral entry into host cell	Induction of endosome membrane permeabilization triggered by an interaction between the host membrane and a membrane-penetration protein associated with the capsid. Occurs after internalization of the virus through the endosomal pathway, and results in delivery of the virus contents into the host cell cytoplasm.	tmpzr1t_l9r_go_relaxed.owl	viral entry into host cell via clathrin-mediated endocytosis followed by endosome membrane permeabilization|viral entry into host cell via caveolae-mediated endocytosis followed by endosome membrane							jl	2010-06-02T02:40:25Z			GO:0075518		biological_process											owl:Class	
GO:0102583	biolink:NamedThing	cyanidin 3-O-glucoside-(2''-O-xyloside) 6''-O-acyltransferase activity	Catalysis of the reaction: cyanidin 3-O-beta-D-sambubioside + 4-coumaryl-CoA <=> cyanidin 3-O-[2''-O-xylosyl) 6''-O-(p-coumaroyl) glucoside + coenzyme A.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-15329									molecular_function											owl:Class	
GO:1990227	biolink:NamedThing	paranodal junction maintenance	The maintenance of a paranodal junction, a highly specialized cell-cell junction found in vertebrates, which forms between a neuron and a glial cell, and has structural similarity to Drosophila septate junctions. A paranodal junction flanks the node of Ranvier in myelinated nerve, electrically isolates the myelinated from unmyelinated nerve segments, and physically separates the voltage-gated sodium channels at the node from the cluster of potassium channels underneath the myelin sheath.	tmpzr1t_l9r_go_relaxed.owl	axoglial septate junction maintenance|paranodal septate maintenance|paranodal axoglial junction maintenance							pr	2013-11-07T20:01:46Z					biological_process											owl:Class	
GO:0033709	biolink:NamedThing	D-arabinitol dehydrogenase, D-ribulose forming (NADP+) activity	Catalysis of the reaction: D-arabinitol + NADP+ = D-ribulose + NADPH + H+.	tmpzr1t_l9r_go_relaxed.owl	D-arabinitol:NADP+ dehydrogenase activity|D-arabinitol dehydrogenase 1 activity|ARD1p|NADP+-dependent D-arabinitol dehydrogenase activity				KEGG_REACTION:R07144|RHEA:11868|MetaCyc:RXN-7972									molecular_function											owl:Class	
GO:0140024	biolink:NamedThing	plus-end-directed endosome transport along mitotic spindle midzone microtubule	The directed movement of an endosome towards the plus end of a microtubule, mediated by motor proteins. This process begins with the attachment of an endosome to a microtubule, and ends when the endosome reaches its final destination.	tmpzr1t_l9r_go_relaxed.owl								pg	2017-04-29T11:34:23Z					biological_process											owl:Class	
GO:0034778	biolink:NamedThing	2-hydroxy-4-isopropenylcyclohexane-1-carboxyl-CoA dehydrogenase activity	Catalysis of the reaction: 2-hydroxy-4-isopropenylcyclohexane-1-carboxyl-CoA = 4-isopropenyl-2-ketocyclohexane-1-carboxyl-CoA + 2 H+ + 2 e-.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r1003									molecular_function											owl:Class	
GO:0102324	biolink:NamedThing	2-hydroxy-6-oxo-nona-2,4-dienoate hydrolase activity	Catalysis of the reaction: 2-hydroxy-6-oxo-nona-2,4-dienoate + H2O = butyrate + 2-oxopent-4-enoate + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-13157									molecular_function											owl:Class	
GO:0004582	biolink:NamedThing	dolichyl-phosphate beta-D-mannosyltransferase activity	Catalysis of the reaction: GDP-mannose + dolichyl phosphate = GDP + dolichyl D-mannosyl phosphate.	tmpzr1t_l9r_go_relaxed.owl	GDPMan:DolP mannosyltransferase activity|guanosine diphosphomannose-dolichol phosphate mannosyltransferase activity|dolichyl mannosyl phosphate synthase activity|DPM synthase activity|GDPmannose-dolichylmonophosphate mannosyltransferase activity|dolichol-phosphate mannosyltransferase activity|GDP-mannose-dolichol phosphate mannosyltransferase activity|GDP-mannose:dolichyl-phosphate beta-D-mannosyltransferase activity|dolichyl-phospho-mannose synthase activity|dolichol-phosphate-mannose synthase activity|dolichol phosphate mannose synthase activity|dolichyl-phosphate mannose synthase activity|GDPmannose:dolichyl-phosphate mannosyltransferase activity|mannosylphosphodolichol synthase activity|mannosylphosphoryldolichol synthase activity|dolichyl phosphate mannosyltransferase activity|dolichol-phosphate mannose synthase activity				Reactome:R-HSA-4719354|Reactome:R-HSA-4719375|Reactome:R-HSA-162721|Reactome:R-HSA-4717406|EC:2.4.1.83|MetaCyc:2.4.1.83-RXN|RHEA:21184									molecular_function											owl:Class	
GO:0030592	biolink:NamedThing	DNA ADP-ribosylation	The covalent attachment of an ADP-ribosyl group to a residue in double-stranded DNA.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/16614												biological_process											owl:Class	
GO:0052604	biolink:NamedThing	delta-tocopherol cyclase activity	Catalysis of the reaction: 2-methyl-6-phytyl-1,4-benzoquinone = delta-tocopherol.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-2561|RHEA:37987|KEGG_REACTION:R07503									molecular_function											owl:Class	
GO:1901763	biolink:NamedThing	oxytetracycline biosynthetic process	The chemical reactions and pathways resulting in the formation of oxytetracycline.	tmpzr1t_l9r_go_relaxed.owl	oxytetracycline synthesis|oxytetracycline formation|oxytetracycline anabolism|oxytetracycline biosynthesis							yaf	2013-01-15T09:52:59Z					biological_process											owl:Class	
GO:0002459	biolink:NamedThing	adaptive immune response based on somatic recombination of immune receptors built from leucine-rich repeat domains	An immune response mediated by lymphocytes expressing specific receptors for antigen produced through a somatic diversification process that includes somatic recombination of variable lymphocyte receptors (VLR) incorporating leucine-rich repeat (LRR) domains, and allowing for enhanced responses upon subsequent exposures to the same antigen (immunological memory). Examples of this process are found in jawless fish, including the lampreys (Petromyzontidae) and hagfishes (Myxinidae).	tmpzr1t_l9r_go_relaxed.owl	adaptive immune response based on somatic recombination of variable lymphocyte receptors built from leucine-rich repeat domains|adaptive immune response in jawless fish|adaptive immune response based on somatic recombination of VLR built from LRR domains													biological_process											owl:Class	
GO:0080068	biolink:NamedThing	5-methylthiopentyl-desulfoglucosinolate sulfotransferase activity	Catalysis of the reaction: 5-methylthiopentyl-desulfoglucosinolate + 3'-phosphoadenosine 5'-phosphosulfate = 5-methylthiopentyl-glucosinolate + adenosine 3',5'-bisphosphate.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXNQT-4330			dhl	2009-04-13T04:06:59Z					molecular_function											owl:Class	
GO:0030281	biolink:NamedThing	structural constituent of cutaneous appendage	The action of a molecule that contributes to the structural integrity of cutaneous epidermal structures such as hairs, scales, or feathers.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0018737	biolink:NamedThing	2-ketocyclohexane-1-carboxyl-CoA hydrolase activity	Catalysis of the reaction: 2-ketocyclohexane-1-carboxyl-CoA + H2O = pimeloyl-CoA.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0193									molecular_function											owl:Class	
GO:0090583	biolink:NamedThing	protein-phosphocysteine-D-sorbitol-phosphotransferase system transporter activity	Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein S-phosphocysteine + D-sorbitol(out) = protein cysteine + D-sorbitol-1-phosphate(in).	tmpzr1t_l9r_go_relaxed.owl								tb	2014-06-04T16:22:31Z					molecular_function											owl:Class	
GO:0004654	biolink:NamedThing	polyribonucleotide nucleotidyltransferase activity	Catalysis of the reaction: RNA(n+1) + phosphate <=> RNA(n) + a nucleoside diphosphate.	tmpzr1t_l9r_go_relaxed.owl	polynucleotide phosphorylase activity|polyribonucleotide:phosphate nucleotidyltransferase activity|polyribonucleotide phosphorylase activity|nucleoside diphosphate:polynucleotidyl transferase activity				EC:2.7.7.8|RHEA:22096|MetaCyc:2.7.7.8-RXN									molecular_function											owl:Class	
GO:0102181	biolink:NamedThing	4alpha-formyl-stigmasta-7,24(241)-dien-3beta-ol-methyl oxidase activity	Catalysis of the reaction: 4alpha-formyl-stigmasta-7,24(241)-dien-3beta-ol + NADH + O2 <=> 4alpha-carboxy-stigmasta-7,24(241)-dien-3beta-ol + NAD + H2O.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-11937|RHEA:59040									molecular_function											owl:Class	
GO:0034752	biolink:NamedThing	cytosolic aryl hydrocarbon receptor complex	An aryl hydrocarbon receptor complex found in the cytosol, in which the ligand-binding subunit AhR is not bound to ligand; consists of AhR, two molecules of HSP90, the protein kinase c-Src, and the immunophilin XAP2/AIP.	tmpzr1t_l9r_go_relaxed.owl	9S-cytosolic aryl hydrocarbon (Ah) receptor non-ligand activated complex|cytosolic AhR complex|cytosolic AHRC													cellular_component											owl:Class	
GO:0021665	biolink:NamedThing	rhombomere 5 structural organization	The process that contributes to creating the structural organization of rhombomere 5. This process pertains to the physical shaping of a rudimentary structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.	tmpzr1t_l9r_go_relaxed.owl	rhombomere 5 structural organisation													biological_process											owl:Class	
GO:0097527	biolink:NamedThing	necroptotic signaling pathway	A series of molecular signals which triggers the necroptotic death of a cell. The pathway starts with reception of a signal, is characterized by activation of receptor-interacting serine/threonine-protein kinase 1 and/or 3 (RIPK1/3, also called RIP1/3), and ends when the execution phase of necroptosis is triggered.	tmpzr1t_l9r_go_relaxed.owl	necroptotic signal transduction|necroptosis signaling|necroptosis signaling pathway|necroptotic signalling pathway					Gene products that may be annotated to this term include: 1) ligands such as TNF-alpha; 2) receptors such as TNFR (though care should be taken because TNF-alpha and TNFR may also be involved in non-necroptotic processes); 3) signaling molecules such as TNFR-associated death domain (TRADD), receptor-interacting protein kinase 1 (RIP1), cellular inhibitor of apoptosis 1 (cIAP1), cIAP2, TNFR-associated factor 2 (TRAF2) and TRAF5. Within the so-called complex I, RIP1 is polyubiquitinated by cIAPs, thereby providing a docking site for the recruitment of transforming growth factor beta (TGFbeta)-activated kinase 1 (TAK1), TAK1-binding protein 2 (TAB2) and TAB3 (which together deliver a pro-survival signal by activating the transcription factor NF-kB). In some pathophysiological and experimental settings, and in particular when caspase-8 is absent or when caspases are inhibited by pharmacological agents, cylindromatosis (CYLD)-deubiquitinated RIP1 engage in physical and functional interactions with its homolog RIP3, ultimately activating the execution of necrotic cell death. (The pathway downstream of RIPK3 remains largely unknown, although ROS generation, calcium overload, and the opening of the mitochondrial permeability transition pore have been implicated (PMID:22265414)). A necroptotic signaling pathway may also be induced by alkylating DNA damage (possibly by the overactivation of poly(ADP-ribose) polymerase 1, PARP1). This is sometimes referred to as PARP-dependent cell death or parthanatos; it is still being debated if it constitutes an independent cell death modality.		pr	2013-11-05T14:17:28Z					biological_process											owl:Class	
GO:1990107	biolink:NamedThing	thiazole synthase activity	Catalysis of the reaction: 1-deoxy-D-xylulose 5-phosphate + 2-iminoacetate + thiocarboxy-adenylate-[sulfur-carrier protein ThiS] = 2-[(2R,5Z)-2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate + [sulfur-carrier protein ThiS] + 2 H2O.	tmpzr1t_l9r_go_relaxed.owl	1-deoxy-D-xylulose 5-phosphate:thiol sulfurtransferase activity				RHEA:26297	H2S can provide the sulfur in vitro. Part of the pathway for thiamine biosynthesis.		pr	2013-05-28T12:36:04Z					molecular_function											owl:Class	
GO:0000744	biolink:NamedThing	karyogamy involved in conjugation with mutual genetic exchange	During sexual reproduction, the creation of a single nucleus from two nuclei as a result of fusing the nuclear envelopes that surround each nuclei. This takes place following the mutual exchange of one of the two nuclei produced by the mitosis that follows the second meiotic nuclear division. This occurs in ciliated protozoans such as Tetrahymena.	tmpzr1t_l9r_go_relaxed.owl	karyogamy involved in conjugation without cellular fusion	https://github.com/geneontology/go-ontology/issues/16248												biological_process											owl:Class	
GO:0042071	biolink:NamedThing	leucokinin receptor activity	Combining with a leucokinin, any of several octapeptide hormones found in insects, and transmitting the signal to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0102858	biolink:NamedThing	1-18:2-2-18:3-phosphatidylcholine desaturase activity	Catalysis of the reaction: 1-18:2-2-18:3-phosphatidylcholine + O2 + a reduced electron acceptor <=> 1-18:3-2-18:3-phosphatidylcholine + 2 H2O + an oxidized electron acceptor.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-8325									molecular_function											owl:Class	
GO:0039617	biolink:NamedThing	T=3 icosahedral viral capsid	The protein coat that surrounds the infective nucleic acid in some virus particles where the subunits (capsomeres) are arranged to form an icosahedron with T=3 symmetry. The T=3 capsid is composed of 12 pentameric and 20 hexameric capsomeres.	tmpzr1t_l9r_go_relaxed.owl					VZ:806			bf	2012-07-18T02:07:40Z					cellular_component											owl:Class	
GO:0032783	biolink:NamedThing	super elongation complex	A transcription elongation factor complex that increases the overall rate of RNA polymerase II transcription elongation by suppressing transient polymerase pausing. At minimum, the complex contains a transcription factor of the ELL family, an EAF protein, and an AFF family protein or distant relative and most likely also P-TEFb and AF9 or ENL. The complex is conserved from yeast to humans. In Schizosaccharomyces pombe it contains Ell1, Eaf1, and Ebp1, but it is absent from S. cerevisiae.	tmpzr1t_l9r_go_relaxed.owl	ELL-EAF-EBP complex|ELL-EAF complex	https://github.com/geneontology/go-ontology/issues/17203												cellular_component											owl:Class	
GO:0019780	biolink:NamedThing	FAT10 activating enzyme activity	Catalysis of the activation of the small ubiquitin-related modifier FAT10, through the formation of an ATP-dependent high-energy thiolester bond.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0047821	biolink:NamedThing	D-glutamate oxidase activity	Catalysis of the reaction: D-glutamate + H2O + O2 = 2-oxoglutarate + NH3 + H2O2.	tmpzr1t_l9r_go_relaxed.owl	D-glutamic oxidase activity|D-glutamic acid oxidase activity|D-glutamate:oxygen oxidoreductase (deaminating)				KEGG_REACTION:R00279|EC:1.4.3.7|MetaCyc:D-GLUTAMATE-OXIDASE-RXN|RHEA:10028									molecular_function											owl:Class	
GO:1990827	biolink:NamedThing	deaminase binding	Binding to an enzyme that catalyzes the removal of an amino group from a substrate, producing ammonia (NH3).	tmpzr1t_l9r_go_relaxed.owl								sl	2015-08-19T23:48:32Z					molecular_function											owl:Class	
GO:0035237	biolink:NamedThing	corazonin receptor activity	Combining with the neuropeptide corazonin to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0005093	biolink:NamedThing	Rab GDP-dissociation inhibitor activity	Prevents the dissociation of GDP from the small GTPase Rab, thereby preventing GTP from binding.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0047798	biolink:NamedThing	cyclomaltodextrinase activity	Catalysis of the reaction: H2O + cyclomaltodextrin = linear maltodextrin.	tmpzr1t_l9r_go_relaxed.owl	cyclohexaglucanase activity|cyclodextrinase activity|cycloheptaglucanase activity|cyclomaltodextrin dextrin-hydrolase (decyclizing)				EC:3.2.1.54|RHEA:23980|MetaCyc:CYCLOMALTODEXTRINASE-RXN									molecular_function											owl:Class	
GO:0050189	biolink:NamedThing	phosphoenolpyruvate phosphatase activity	Catalysis of the reaction: H(2)O + phosphoenolpyruvate = phosphate + pyruvate.	tmpzr1t_l9r_go_relaxed.owl	phosphoenolpyruvate phosphohydrolase activity|PEP phosphatase activity				EC:3.1.3.60|RHEA:19997|KEGG_REACTION:R00208|MetaCyc:PHOSPHOENOLPYRUVATE-PHOSPHATASE-RXN									molecular_function											owl:Class	
GO:1990650	biolink:NamedThing	inositol-2,4,5,6-tetrakisphosphate 5-phosphatase activity	Catalysis of the reaction: 1D-myo-inositol 2,4,5,6-tetrakisphosphate + H2O = 1D-myo-inositol 2,4,6-trisphosphate + phosphate.	tmpzr1t_l9r_go_relaxed.owl								al	2015-02-23T11:14:17Z					molecular_function											owl:Class	
GO:0102606	biolink:NamedThing	octat-9-en-7-ol 5-monooxygenase activity	Catalysis of the reaction: cyclooctat-9-en-7-ol + O2 + NADPH + H+ <=> cyclooctat-9-en-5,7-diol + H2O + NADP.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-15431|RHEA:56820									molecular_function											owl:Class	
GO:0003834	biolink:NamedThing	beta-carotene 15,15'-dioxygenase activity	Catalysis of the reaction: all-trans-beta-carotene + O2 = 2 all-trans-retinal.	tmpzr1t_l9r_go_relaxed.owl	carotene dioxygenase activity|carotene 15,15'-dioxygenase activity|beta-carotene 15,15'-monooxygenase activity	https://github.com/geneontology/go-ontology/issues/21765			KEGG_REACTION:R00032|Reactome:R-HSA-975635|EC:1.13.11.63|MetaCyc:BETA-CAROTENE-1515-DIOXYGENASE-RXN|RHEA:32887	Formerly EC:1.13.11.n2, EC:1.13.11.21 and then EC 1.14.99.36.								molecular_function											owl:Class	
GO:0035646	biolink:NamedThing	endosome to melanosome transport	The directed movement of substances from endosomes to the melanosome, a specialised lysosome-related organelle.	tmpzr1t_l9r_go_relaxed.owl								bf	2011-01-24T01:30:07Z					biological_process											owl:Class	
GO:1905719	biolink:NamedThing	protein localization to perinuclear region of cytoplasm	A process in which a protein is transported to, or maintained in, a location within the perinuclear region of the cytoplasm.	tmpzr1t_l9r_go_relaxed.owl	protein localization in perinuclear region of cytoplasm|protein localisation in perinuclear region of cytoplasm|protein localization to perinuclear cytoplasm|protein localisation to perinuclear region of cytoplasm							mah	2016-11-24T16:51:55Z					biological_process											owl:Class	
GO:0060776	biolink:NamedThing	simple leaf morphogenesis	The leaf morphogenesis process which results in the shaping of a simple leaf. A simple leaf is a leaf in which the lamina is undivided.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-07-25T07:08:44Z					biological_process											owl:Class	
GO:0051062	biolink:NamedThing	UDP reductase activity	Catalysis of the reaction: dUDP + thioredoxin disulfide + H2O = UDP + thioredoxin.	tmpzr1t_l9r_go_relaxed.owl	UDP reduction				RHEA:28026|MetaCyc:UDPREDUCT-RXN									molecular_function											owl:Class	
GO:1990592	biolink:NamedThing	protein K69-linked ufmylation	A protein ufmylation process in which a polymer of the ubiquitin-like protein UFM1 is formed by linkages between lysine residues at position 69 of the UFM1 monomers, is added to a protein.	tmpzr1t_l9r_go_relaxed.owl								jl	2014-12-15T17:01:23Z					biological_process											owl:Class	
GO:0103097	biolink:NamedThing	CYP79F1 trihomomethionine monooxygenase activity	Catalysis of the reaction: trihomomethionine + 2 O2 + 2 NADPH + 2 H+ <=> 3 H2O + carbon dioxide + 2 NADP + 6-methylthiohexanaldoxime.	tmpzr1t_l9r_go_relaxed.owl					RHEA:32723|MetaCyc:RXNQT-4310									molecular_function											owl:Class	
GO:0003836	biolink:NamedThing	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity	Catalysis of the reaction: CMP-N-acetylneuraminate + beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl-R = CMP + alpha-N-acetylneuraminyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl-R.	tmpzr1t_l9r_go_relaxed.owl	CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase activity|CMP-N-acetylneuraminate:beta-D-galactoside alpha-2,3-N-acetylneuraminyl-transferase activity				RHEA:21616|Reactome:R-HSA-4084984|Reactome:R-HSA-2046285|Reactome:R-HSA-1022129|Reactome:R-HSA-3656258|Reactome:R-HSA-1912378|Reactome:R-HSA-981497|Reactome:R-HSA-9603987|MetaCyc:2.4.99.4-RXN|Reactome:R-HSA-9605600|EC:2.4.99.4									molecular_function											owl:Class	
GO:1990137	biolink:NamedThing	plant seed peroxidase activity	Catalysis of the reaction: R1H + R2OOH = R1OH + R2OH.	tmpzr1t_l9r_go_relaxed.owl	peroxygenase activity				EC:1.11.2.3|MetaCyc:RXN-11819			tb	2013-07-03T12:49:20Z					molecular_function											owl:Class	
GO:0000343	biolink:NamedThing	plastid-encoded plastid RNA polymerase complex A	A plastid-encoded DNA-directed RNA polymerase complex that resembles eubacterial multisubunit RNA polymerases, with a core composed of alpha, beta, and beta-prime subunits. An additional subunit, a sigma factor, is required for promoter recognition. PEP-A is generated from the PEP-B form during chloroplast maturation to generate a complex composed of at least thirteen polypeptides that is not sensitive to the antibiotic rifampicin, like its precursor form the PEP-B complex.	tmpzr1t_l9r_go_relaxed.owl	PEP-A													cellular_component											owl:Class	
GO:0090547	biolink:NamedThing	response to low humidity	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of low humidity stimulus, reduced moisture in the atmosphere.	tmpzr1t_l9r_go_relaxed.owl								tb	2013-04-17T13:46:28Z					biological_process											owl:Class	
GO:0050625	biolink:NamedThing	2-hydroxy-1,4-benzoquinone reductase activity	Catalysis of the reaction: 2-hydroxy-1,4-benzoquinone + 2 H(+) + NADH = benzene-1,2,4-triol + NAD(+).	tmpzr1t_l9r_go_relaxed.owl	hydroxybenzoquinone reductase activity|2-hydroxy-1,4-benzoquinone:NADH oxidoreductase activity|1,2,4-trihydroxybenzene:NAD+ oxidoreductase activity|1,2,4-trihydroxybenzene:NAD oxidoreductase activity|NADH:2-hydroxy-1,4-benzoquinone oxidoreductase activity				KEGG_REACTION:R05399|MetaCyc:1.6.5.7-RXN|UM-BBD_reactionID:r0667|EC:1.6.5.7|RHEA:12428							GO:0018540		molecular_function											owl:Class	
GO:0014883	biolink:NamedThing	transition between fast and slow fiber	The process of conversion of fast-contracting muscle fibers to a slower character. This may involve slowing of contractile rate, slow myosin gene induction, increase in oxidative metabolic properties, altered electrophysiology and altered innervation. This process also regulates skeletal muscle adapatation.	tmpzr1t_l9r_go_relaxed.owl	transition fast-slow fibre|transition fast-slow fiber|transition between fast and slow fibre													biological_process											owl:Class	
GO:0047603	biolink:NamedThing	acetoacetyl-CoA hydrolase activity	Catalysis of the reaction: acetoacetyl-CoA + H(2)O = acetoacetate + CoA + H(+).	tmpzr1t_l9r_go_relaxed.owl	acetoacetyl coenzyme A deacylase activity|acetoacetyl coenzyme A hydrolase activity|acetoacetyl CoA deacylase activity				RHEA:15673|KEGG_REACTION:R01358|MetaCyc:ACETOACETYL-COA-HYDROLASE-RXN|EC:3.1.2.11									molecular_function											owl:Class	
GO:0033890	biolink:NamedThing	ribonuclease D activity	Catalysis of the exonucleolytic cleavage that removes extra residues from the 3'-terminus of tRNA to produce 5'-mononucleotides.	tmpzr1t_l9r_go_relaxed.owl	RNase D activity				MetaCyc:3.1.13.5-RXN|EC:3.1.13.5									molecular_function											owl:Class	
GO:0008997	biolink:NamedThing	ribonuclease R activity	Catalysis of the reaction: RNA + H2O = 5'-phosphomononucleotides. Cleaves RNA in the 3' to 5' direction, leaving an undigested core of 3-5 nucleotides.	tmpzr1t_l9r_go_relaxed.owl					EC:3.1.11.-									molecular_function											owl:Class	
GO:0002334	biolink:NamedThing	transitional two stage B cell differentiation	The process in which immature B cells from the bone marrow acquire the specialized features of T2 stage B cells in the spleen. T2 stage B cells express CD23 but not CD21.	tmpzr1t_l9r_go_relaxed.owl	T2 stage B cell differentiation|transitional two stage B cell development|transitional two stage B-cell differentiation|transitional two stage B-lymphocyte differentiation|transitional two stage B lymphocyte differentiation					Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.								biological_process											owl:Class	
GO:0018713	biolink:NamedThing	3-ketopimelyl-CoA thiolase activity	Catalysis of the reaction: 3-ketopimeloyl-CoA + CoA = glutaryl-CoA + acetyl-CoA.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-8032|UM-BBD_reactionID:r0197									molecular_function											owl:Class	
GO:0046592	biolink:NamedThing	polyamine oxidase activity	Catalysis of the oxidative degradation or interconversion of polyamines.	tmpzr1t_l9r_go_relaxed.owl	1-N-acetylspermidine:oxygen oxidoreductase (deaminating)|N1-acetylspermidine:oxygen oxidoreductase (deaminating)				MetaCyc:POLYAMINE-OXIDASE-RXN									molecular_function											owl:Class	
GO:0055058	biolink:NamedThing	symmetric neuroblast division	The process resulting in the physical partitioning and separation of a neuroblast into two equi-potent daughter cells.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0043263	biolink:NamedThing	cellulosome	An extracellular multi-enzyme complex containing up to 11 different enzymes aligned on a non-catalytic scaffolding glycoprotein. Functions to hydrolyze cellulose.	tmpzr1t_l9r_go_relaxed.owl	scaffoldin complex				Wikipedia:Cellulosome							GO:1990296		cellular_component											owl:Class	
GO:0016161	biolink:NamedThing	beta-amylase activity	Catalysis of the reaction: (1,4-alpha-D-glucosyl)(n+1) + H2O = (1,4-alpha-D-glucosyl)(n-1) + alpha-maltose. This reaction is the hydrolysis of 1,4-alpha-glucosidic linkages in polysaccharides so as to remove successive maltose units from the non-reducing ends of the chains.	tmpzr1t_l9r_go_relaxed.owl	glycogenase activity|saccharogen amylase activity|1,4-alpha-D-glucan maltohydrolase activity|beta amylase activity				MetaCyc:RXN-1827|EC:3.2.1.2|MetaCyc:RXN-12279									molecular_function											owl:Class	
GO:0005113	biolink:NamedThing	patched binding	Binding to a patched (ptc) protein, a receptor for hedgehog proteins.	tmpzr1t_l9r_go_relaxed.owl	ptc binding|ptc ligand|patched ligand													molecular_function											owl:Class	
GO:0050078	biolink:NamedThing	malonate CoA-transferase activity	Catalysis of the reaction: acetyl-CoA + malonate = acetate + malonyl-CoA.	tmpzr1t_l9r_go_relaxed.owl	acetyl-CoA:malonate CoA-transferase activity|malonate coenzyme A-transferase activity				RHEA:18817|EC:2.8.3.3|MetaCyc:MALONATE-COA-TRANSFERASE-RXN|KEGG_REACTION:R00743									molecular_function											owl:Class	
GO:0014728	biolink:NamedThing	regulation of the force of skeletal muscle contraction	Any process that modulates the frequency, rate or extent of the force of skeletal muscle contraction. The force of skeletal muscle contraction is produced by acto-myosin interaction processes through the formation of cross bridges.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0102630	biolink:NamedThing	gossypetin 8-methyl ester 3'-O-methyltransferase activity	Catalysis of the reaction: 3',4',5,7-pentahydroxy-8-methoxyflavon-3-olate + S-adenosyl-L-methionine  <=> gossypetin 3',8-dimethyl ether + S-adenosyl-L-homocysteine  + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-15536									molecular_function											owl:Class	
GO:0051211	biolink:NamedThing	anisotropic cell growth	The process in which a cell irreversibly increases in size in one or more axes, where the growth rate varies according to the direction of growth. Growth may be limited to a particular axis, axes, or to particular locations on the surface of the cell.	tmpzr1t_l9r_go_relaxed.owl	non-isotropic cell growth													biological_process											owl:Class	
GO:1990808	biolink:NamedThing	F-bar domain binding	Binding to an F-BAR domain of a protein, a domain of about 60 residues that occurs in a wide range of cytoskeletal proteins.	tmpzr1t_l9r_go_relaxed.owl								vw	2015-07-21T18:43:00Z					molecular_function											owl:Class	
GO:0034829	biolink:NamedThing	2-hydroxydec-2,4-diene-1,10-dioate hydratase activity	Catalysis of the reaction: 2-hydroxydec-2,4-diene-1,10-dioate + H2O = (2Z)-2,4-dihydroxydec-2-enedioate.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r1172									molecular_function											owl:Class	
GO:0062052	biolink:NamedThing	starch granule initiation	The sequence of events that initiates (or primes) the synthesis of semi-crystalline starch granules within photosynthetic chloroplasts or non-photosynthetic amyloplasts.	tmpzr1t_l9r_go_relaxed.owl								dph	2018-06-08T17:18:57Z					biological_process											owl:Class	
GO:0055091	biolink:NamedThing	phospholipid homeostasis	Any process involved in the maintenance of an internal steady state of phospholipid within an organism or cell.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0019535	biolink:NamedThing	ferric-vibriobactin transmembrane transporter activity	Enables the transfer of ferric-vibriobactin ions from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0071596	biolink:NamedThing	ubiquitin-dependent protein catabolic process via the N-end rule pathway	The chemical reactions and pathways resulting in the breakdown of a protein or peptide covalently tagged with ubiquitin, via the N-end rule pathway. In the N-end rule pathway, destabilizing N-terminal residues (N-degrons) in substrates are recognized by E3 ligases (N-recognins), whereupon the substrates are linked to ubiquitin and then delivered to the proteasome for degradation.	tmpzr1t_l9r_go_relaxed.owl	ubiquitin-dependent protein breakdown via the N-end rule pathway|ubiquitin-dependent protein degradation via the N-end rule pathway|ubiquitin-dependent protein catabolism via the N-end rule pathway							mah	2010-01-29T03:01:09Z					biological_process											owl:Class	
GO:0052367	biolink:NamedThing	disruption by host of symbiont cellular component	The chemical reactions and pathways performed by an organism resulting in the breakdown of cellular components of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	degradation of symbiont cellular component by organism|catabolism of symbiont structural constituent by organism|catabolism of symbiont cellular component by organism|disassembly by host of symbiont cellular component													biological_process											owl:Class	
GO:0032867	biolink:NamedThing	L-arabinose:NADP reductase activity	Catalysis of the reaction: L-arabitol + NADP+ = L-arabinose + NADPH + H+.	tmpzr1t_l9r_go_relaxed.owl	arabinose:NADP reductase activity|arabinose reductase activity				RHEA:25229|KEGG_REACTION:R01759|MetaCyc:RXN-8772|SABIO-RK:1858									molecular_function											owl:Class	
GO:0021998	biolink:NamedThing	neural plate mediolateral regionalization	The process that regulates the coordinated growth and differentiation that establishes the non-random mediolateral spatial arrangement of the neural plate.	tmpzr1t_l9r_go_relaxed.owl	neural plate mediolateral pattern formation													biological_process											owl:Class	
GO:0102621	biolink:NamedThing	emindole-SB NADPH:oxygen oxidoreductase (14,15-epoxidizing) activity	Catalysis of the reaction: emindole-SB + O2 + NADPH + H+ <=> 14,15-epoxyemindole-SB + NADP + H2O.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-15496									molecular_function											owl:Class	
GO:0031722	biolink:NamedThing	hemoglobin beta binding	Binding to a hemoglobin beta chain.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0010540	biolink:NamedThing	basipetal auxin transport	The unidirectional movement of auxin from the apex to base of an organ, including the shoot, leaf, primary root, or lateral root.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0042614	biolink:NamedThing	CD70 receptor binding	Binding to a CD70, a receptor found on the surface of most activated B cells and some activated T cells.	tmpzr1t_l9r_go_relaxed.owl	CD27 receptor activity|CD27L binding													molecular_function											owl:Class	
GO:0080106	biolink:NamedThing	7-methylthiopropyl glucosinolate S-oxygenase activity	Catalysis of the reaction: 7-methylthiopropyl-glucosinolate = 7-methylsulfinylpropyl-glucosinolate.	tmpzr1t_l9r_go_relaxed.owl								dhl	2009-04-23T04:29:37Z					molecular_function											owl:Class	
GO:0071820	biolink:NamedThing	N-box binding	Binding to an N-box, a DNA motif with the consensus sequence CACNAG that is found in the promoters of genes expressed preferentially at synapses.	tmpzr1t_l9r_go_relaxed.owl	N-box promoter binding|N box binding					Note that as agreed during the transcription overhaul, terms specifying binding to specific transcription regulatory motifs are no longer being created. The level of specificity GO has decided to go to is the "core promoter", "core promoter proximal region" and "enhancer". To capture more detail, please consider using column 16.		mah	2010-09-07T11:55:32Z					molecular_function											owl:Class	
GO:0102930	biolink:NamedThing	4-hydroxybenzoate geranyltransferase activity	Catalysis of the reaction: geranyl diphosphate + 4-hydroxybenzoic acid = 3-geranyl-4-hydroxybenzoate + diphosphoric acid.	tmpzr1t_l9r_go_relaxed.owl					EC:2.5.1.93|RHEA:27854|MetaCyc:RXN-8920									molecular_function											owl:Class	
GO:0120326	biolink:NamedThing	appressorium-mediated entry into host	Penetration by a symbiont into a host organism via an appressorium. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	appressorium-mediated penetration into host|appressorium-mediated host invasion|appressorium-mediated host penetration|appressorium-mediated invasion into host	https://github.com/geneontology/go-ontology/issues/21505						krc	2021-08-04T00:48:35Z					biological_process											owl:Class	
GO:0001697	biolink:NamedThing	histamine-induced gastric acid secretion	The regulated release of gastric acid induced by the interaction of histamine with H2 type receptor receptors with subsequent activation of adenylate cyclase and elevation of intracellular cyclic AMP.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0052926	biolink:NamedThing	dol-P-Man:Man(6)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity	Catalysis of the reaction: alpha-D-man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-(alpha-D-Man-(1->3)-alpha-D-Man-(1->6))-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-diphosphodolichol + dolichyl D-mannosyl phosphate = H(+) + alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-(alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-alpha-D-Man-(1->6))-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-diphosphodolichol + dolichyl phosphate.	tmpzr1t_l9r_go_relaxed.owl	dolichylphosphomannose-dependent ALG9 mannosyltransferase activity				RHEA:29531|MetaCyc:RXN-5467|EC:2.4.1.259|KEGG_REACTION:R06259									molecular_function											owl:Class	
GO:0102276	biolink:NamedThing	2-oxoglutarate oxygenase/decarboxylase (ethylene-forming) activity	Catalysis of the reaction: 2-oxoglutarate(2-) + O2 + 2 H+ <=> ethene + 3 carbon dioxide + H2O.	tmpzr1t_l9r_go_relaxed.owl					RHEA:31523|EC:1.13.12.19|MetaCyc:RXN-12538									molecular_function											owl:Class	
GO:0018731	biolink:NamedThing	1-oxa-2-oxocycloheptane lactonase activity	Catalysis of the reaction: 1-oxa-2-oxocycloheptane + H2O = 6-hydroxyhexanoate.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0167									molecular_function											owl:Class	
GO:0052726	biolink:NamedThing	inositol-1,3,4-trisphosphate 5-kinase activity	Catalysis of the reaction: 1D-myo-inositol 1,3,4-trisphosphate + ATP = 1D-myo-inositol 1,3,4,5-tetrakisphosphate + ADP + 2 H(+).	tmpzr1t_l9r_go_relaxed.owl	IP3 5-kinase activity|inositol-trisphosphate 5-kinase activity|ATP:1D-myo-inositol-1,3,4-trisphosphate 5-phosphotransferase activity|ins(1,3,4)P(3) 5-kinase activity|inositol 1,3,4-trisphosphate 5-kinase activity|Ins(1,3,4)P3 5-kinase activity|1D-myo-inositol-trisphosphate 5-kinase activity				Reactome:R-HSA-1855172|EC:2.7.1.159|KEGG_REACTION:R03428|RHEA:13253|Reactome:R-HSA-994140|MetaCyc:2.7.1.139-RXN			ai	2011-08-16T12:43:11Z					molecular_function											owl:Class	
GO:0140549	biolink:NamedThing	spore inner membrane	The membrane surrounding the spore core (endospore core) that separates it from its external environment.	tmpzr1t_l9r_go_relaxed.owl	spore membrane	https://github.com/geneontology/go-ontology/issues/20359						pg	2020-11-12T10:00:15Z					cellular_component											owl:Class	
GO:0047753	biolink:NamedThing	choline-sulfatase activity	Catalysis of the reaction: choline sulfate + H(2)O = choline + H(+) + sulfate.	tmpzr1t_l9r_go_relaxed.owl	choline-sulphatase activity|choline-sulfate sulfohydrolase activity				KEGG_REACTION:R01028|EC:3.1.6.6|RHEA:20820|MetaCyc:CHOLINE-SULFATASE-RXN									molecular_function											owl:Class	
GO:0060063	biolink:NamedThing	Spemann organizer formation at the embryonic shield	Formation of the specialized region of the embryonic shield of the embryo that acts as the main signaling center establishing the teleost body plan.	tmpzr1t_l9r_go_relaxed.owl	Spemann-Mangold organizer formation at the embryonic shield|Spemann's organizer formation at the embryonic shield					Occurs in Teleost fish.								biological_process											owl:Class	
GO:0140285	biolink:NamedThing	endosome fission	The process by which early and late endosomes undergo budding and fission reactions that separate regions destined for lysosomal degradation from carriers to be recycled to the plasma membrane.	tmpzr1t_l9r_go_relaxed.owl								pg	2018-10-30T10:36:33Z					biological_process											owl:Class	
GO:0016034	biolink:NamedThing	maleylacetoacetate isomerase activity	Catalysis of the reaction: 4-maleylacetoacetate = 4-fumarylacetoacetate.	tmpzr1t_l9r_go_relaxed.owl	4-maleylacetoacetate cis-trans-isomerase activity|maleylacetone isomerase activity|maleylacetone cis-trans-isomerase activity|maleylacetoacetic isomerase activity				UM-BBD_reactionID:r0106|MetaCyc:MALEYLACETOACETATE-ISOMERASE-RXN|EC:5.2.1.2|RHEA:14817|Reactome:R-HSA-71173							GO:0018841		molecular_function											owl:Class	
GO:0090534	biolink:NamedThing	calcium ion-transporting ATPase complex	Protein complex that carries out the reaction: ATP + H2O + Ca2+(out) = ADP + phosphate + Ca2+(in).	tmpzr1t_l9r_go_relaxed.owl								tb	2013-02-07T15:52:58Z					cellular_component											owl:Class	
GO:0102990	biolink:NamedThing	5-n-alk(en)ylresorcinol O-methyltransferase activity	Catalysis of the reaction: 5-(pentadeca-8,11,14-trien-1-yl)resorcinol + S-adenosyl-L-methionine  <=> H+ + 5-(pentadeca-8,11,14-trien-1-yl)resorcinol monomethyl ether + S-adenosyl-L-homocysteine.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-9619|RHEA:26325									molecular_function											owl:Class	
GO:0050591	biolink:NamedThing	quinine 3-monooxygenase activity	Catalysis of the reaction: H(+) + NADPH + O(2) + quinine = 3-hydroxyquinine + H(2)O + NADP(+).	tmpzr1t_l9r_go_relaxed.owl	quinine 3-hydroxylase activity|quinine,NADPH:oxygen oxidoreductase activity|nifedipine oxidase activity				MetaCyc:1.14.13.67-RXN|EC:1.14.14.55|RHEA:20149|KEGG_REACTION:R05727									molecular_function											owl:Class	
GO:0018849	biolink:NamedThing	muconate cycloisomerase activity	Catalysis of the reaction: 2,5-dihydro-5-oxofuran-2-acetate = cis,cis-hexadienedioate.	tmpzr1t_l9r_go_relaxed.owl	cis,cis-muconate cycloisomerase activity|muconate cycloisomerase I activity|muconate lactonizing enzyme activity|cis,cis-muconate-lactonizing enzyme|muconate lactonizing enzyme I activity	https://github.com/geneontology/go-ontology/issues/21794			UM-BBD_enzymeID:e0133|EC:5.5.1.1|MetaCyc:MUCONATE-CYCLOISOMERASE-RXN|RHEA:30031									molecular_function											owl:Class	
GO:0031041	biolink:NamedThing	O-glycan processing, core 5	The stepwise addition of carbohydrate or carbohydrate derivative residues to the initially added O-linked residue (usually GalNAc) to form the core 5 O-glycan structure, GalNAc-alpha-(1->3)-GalNAc.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0044568	biolink:NamedThing	secondary cell wall cellulose synthase complex	A large, multimeric protein complex which catalyzes the biosynthesis of cellulose for the plant secondary cell wall. In Arabidopsis, contains the essential component proteins CESA8, CESA7, and CESA4.	tmpzr1t_l9r_go_relaxed.owl	secondary cell-wall cellulose synthase complex|secondary cell wall CESA complex							jl	2012-04-18T12:55:04Z					cellular_component											owl:Class	
GO:0102430	biolink:NamedThing	alpha-linolenate delta5 desaturase activity	Catalysis of the reaction: alpha-linolenate + O2 + a reduced electron acceptor = coniferonate + 2 H2O + an oxidized electron acceptor.	tmpzr1t_l9r_go_relaxed.owl					RHEA:38039|MetaCyc:RXN-13857									molecular_function											owl:Class	
GO:1990311	biolink:NamedThing	type-I cohesin domain binding	Binding to a type-I cohesin domain of a protein. Type-I cohesin domain is the binding partner of type-I dockerin domain.	tmpzr1t_l9r_go_relaxed.owl								tt	2014-03-07T04:47:31Z					molecular_function											owl:Class	
GO:0017075	biolink:NamedThing	syntaxin-1 binding	Binding to a syntaxin-1 SNAP receptor.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0102474	biolink:NamedThing	eriodictyol dibenzoylmethane tautomer 6C-glucosyltransferase activity	Catalysis of the reaction: eriodictyol dibenzoylmethane tautomer + UDP-alpha-D-glucose <=> 6C-beta-D-glucosyl-2-hydroxyeriodictyol + UDP + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-14080									molecular_function											owl:Class	
GO:1990250	biolink:NamedThing	transcription-coupled nucleotide-excision repair, DNA damage recognition complex	A protein complex that is capable of identifying lesions in DNA on the actively transcribed strand of the DNA duplex as well as a small subset of lesions not recognized by the general nucleotide-excision repair pathway. The wide range of substrate specificity suggests that the repair complex recognizes distortions in the DNA helix. It subsequently recruits a nucleotide-excision repair, preincision complex.	tmpzr1t_l9r_go_relaxed.owl								bhm	2013-12-05T16:28:45Z					cellular_component											owl:Class	
GO:0062202	biolink:NamedThing	Labd-13(16),14-diene-9-ol synthase activity	Catalysis of the reaction: peregrinol diphosphate = diphosphate + labd-13(16),14-diene-9-ol.	tmpzr1t_l9r_go_relaxed.owl					RHEA:62184			dph	2020-01-02T15:46:00Z					molecular_function											owl:Class	
GO:0003282	biolink:NamedThing	ventricular septum intermedium development	The progression of the ventricular septum intermedium over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-10-20T10:09:53Z					biological_process											owl:Class	
GO:0080123	biolink:NamedThing	jasmonate-amino synthetase activity	Catalysis of the reaction: jasmonate + an amino acid = an amide-linked jasmonyl-amino acid conjugate. The substrates of this reaction include non-standard amino acids, such as ACC (1-aminocyclopropane-1-carboxylate).	tmpzr1t_l9r_go_relaxed.owl	jasmonate-amino acid conjugate synthetase activity|jasmonate-amino acid synthetase activity|jasmonyl-amino synthetase activity|jasmonate-amido synthetase activity|jasmonate:amino acid synthetase activity|jasmonic acid-amino synthetase activity|ja-amino synthetase activity							dhl	2009-04-28T04:08:35Z					molecular_function											owl:Class	
GO:0034999	biolink:NamedThing	oligosaccharyltransferase II complex	An oligosaccharyltransferase (OST) complex that contains the seven polypeptides found in OST complex I, plus heterotrimeric Sec61alpha-beta-gamma. Of the three forms of mammalian OST complexes identified, the OSTII complex has intermediate affinity for ribosomes.	tmpzr1t_l9r_go_relaxed.owl	OSTCII													cellular_component											owl:Class	
GO:0047697	biolink:NamedThing	beta-alanopine dehydrogenase activity	Catalysis of the reaction: (R)-beta-alanopine + H(2)O + NAD(+) = beta-alanine + H(+) + NADH + pyruvate.	tmpzr1t_l9r_go_relaxed.owl	N-(D-1-carboxyethyl)-beta-alanine:NAD+ oxidoreductase (beta-alanine-forming)|b-alanopine dehydrogenase activity				MetaCyc:BETA-ALANOPINE-DEHYDROGENASE-RXN|EC:1.5.1.26|RHEA:21684|KEGG_REACTION:R00906									molecular_function											owl:Class	
GO:0046577	biolink:NamedThing	long-chain-alcohol oxidase activity	Catalysis of the reaction: 2 long-chain alcohol + O2 = 2 long-chain aldehyde + 2 H2O.	tmpzr1t_l9r_go_relaxed.owl	fatty alcohol:oxygen oxidoreductase activity|fatty alcohol oxidase activity|long-chain fatty alcohol oxidase activity|long-chain fatty acid oxidase activity|long-chain-alcohol:oxygen oxidoreductase activity				RHEA:22756|MetaCyc:LONG-CHAIN-ALCOHOL-OXIDASE-RXN|EC:1.1.3.20									molecular_function											owl:Class	
GO:0071567	biolink:NamedThing	UFM1 hydrolase activity	Catalysis of the hydrolysis of UFM1, a small ubiquitin-related modifier, from previously modified substrates.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-01-20T04:08:34Z					molecular_function											owl:Class	
GO:0033448	biolink:NamedThing	AGG codon-amino acid adaptor activity	A triplet codon-amino acid adaptor activity that recognizes an AGG codon.	tmpzr1t_l9r_go_relaxed.owl	arginine tRNA					Note that in the standard genetic code, AGG codes for arginine.								molecular_function											owl:Class	
GO:0052683	biolink:NamedThing	(Z)-gamma-bisabolene synthase activity	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = (Z)-gamma-bisabolene + diphosphate.	tmpzr1t_l9r_go_relaxed.owl	(2E,6E)-farnesyl-diphosphate diphosphate-lyase [(Z)-gamma-bisabolene-forming] activity				EC:4.2.3.40|MetaCyc:RXN-10005|RHEA:26081									molecular_function											owl:Class	
GO:0032593	biolink:NamedThing	insulin-responsive compartment	A small membrane-bounded vesicle that releases its contents by exocytosis in response to insulin stimulation; the contents are enriched in GLUT4, IRAP and VAMP2.	tmpzr1t_l9r_go_relaxed.owl	GSC|GLUT4 storage compartment|IRC													cellular_component											owl:Class	
GO:0106145	biolink:NamedThing	scopoletin 8-hydroxylase activity	Catalyzes of the reaction: scopoletin + 2-oxoglutarate+O2=fraxetin +succinate+ CO2).	tmpzr1t_l9r_go_relaxed.owl					RHEA:57848|EC:1.14.11.60			hjd	2018-09-07T18:28:16Z					molecular_function											owl:Class	
GO:0071566	biolink:NamedThing	UFM1 activating enzyme activity	Catalysis of the activation of the small ubiquitin-related modifier UFM1, through the formation of an ATP-dependent high-energy thiolester bond.	tmpzr1t_l9r_go_relaxed.owl								mah	2010-01-20T04:06:05Z					molecular_function											owl:Class	
GO:0008677	biolink:NamedThing	2-dehydropantoate 2-reductase activity	Catalysis of the reaction: (R)-pantoate + NADP(+) = 2-dehydropantoate + H(+) + NADPH.	tmpzr1t_l9r_go_relaxed.owl	(R)-pantoate:NADP+ 2-oxidoreductase activity|2-oxopantoate reductase activity|ketopantoate reductase activity|ketopantoic acid reductase activity|2-ketopantoic acid reductase activity|2-ketopantoate reductase activity|KPA reductase activity				MetaCyc:2-DEHYDROPANTOATE-REDUCT-RXN|KEGG_REACTION:R02472|RHEA:16233|EC:1.1.1.169									molecular_function											owl:Class	
GO:0018787	biolink:NamedThing	4-chlorobenzoyl-CoA dehalogenase activity	Catalysis of the reaction: 4-chlorobenzoyl-CoA + H2O = 4-hydroxybenzoyl CoA + chloride.	tmpzr1t_l9r_go_relaxed.owl	4-chlorobenzoyl CoA chlorohydrolase activity				MetaCyc:3.8.1.7-RXN|RHEA:14853|EC:3.8.1.7|UM-BBD_enzymeID:e0113									molecular_function											owl:Class	
GO:0044681	biolink:NamedThing	sulfopyruvate decarboxylase complex	A complex of two polypeptides which form a dodecamer (A6B6). Catalyzes the decarboxylation of sulfopyruvic acid to sulfoacetaldehyde. This reaction is involved in coenzyme M biosynthesis.	tmpzr1t_l9r_go_relaxed.owl								jl	2012-08-09T11:12:47Z					cellular_component											owl:Class	
GO:1990323	biolink:NamedThing	collagen type XXIV trimer	A collagen homotrimer of alpha1(XXIV) chains; type XXIV collagen triple helices may participate in regulating type I collagen fibrillogenesis at specific anatomical locations during fetal development.	tmpzr1t_l9r_go_relaxed.owl								bhm	2014-03-14T22:05:53Z					cellular_component											owl:Class	
GO:0060366	biolink:NamedThing	lambdoid suture morphogenesis	The process in which the lambdoid suture is generated and organized.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0102730	biolink:NamedThing	cathasterone hydroxylase activity	Catalysis of the reaction: cathasterone + O2 + a reduced electron acceptor <=> teasterone + H2O + an oxidized electron acceptor.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-716									molecular_function											owl:Class	
GO:1990829	biolink:NamedThing	C-rich single-stranded DNA binding	Binding to C-rich, single-stranded DNA.	tmpzr1t_l9r_go_relaxed.owl	C-rich ssDNA binding							sl	2015-08-20T16:05:12Z					molecular_function											owl:Class	
GO:0009012	biolink:NamedThing	aminoglycoside 3''-adenylyltransferase activity	Catalysis of the reaction: ATP + streptomycin = 3''-adenylylstreptomycin + diphosphate + H(+).	tmpzr1t_l9r_go_relaxed.owl	streptomycin 3''-adenylyltransferase activity|ATP:streptomycin 3''-adenylyltransferase activity|AAD (3'')				RHEA:20245|MetaCyc:STREPTOMYCIN-3-ADENYLYLTRANSFERASE-RXN|EC:2.7.7.47|KEGG_REACTION:R02226									molecular_function											owl:Class	
GO:0102479	biolink:NamedThing	quercetin 3-O-beta:-D-galactosyltransferase activity	Catalysis of the reaction: quercetin-7-olate + UDP-D-galactose <=> quercetin 3-O-beta-D-galactopyranoside + UDP(3-) + H+.	tmpzr1t_l9r_go_relaxed.owl					EC:2.4.1.234|MetaCyc:RXN-14109									molecular_function											owl:Class	
GO:0051117	biolink:NamedThing	ATPase binding	Binding to an ATPase, any enzyme that catalyzes the hydrolysis of ATP.	tmpzr1t_l9r_go_relaxed.owl														molecular_function											owl:Class	
GO:0071058	biolink:NamedThing	alpha3-beta1 integrin-CD151 complex	A protein complex that consists of an alpha3-beta1 integrin complex bound to the tetraspanin CD151.	tmpzr1t_l9r_go_relaxed.owl	ITGA3-ITGB1-CD151 complex							mah	2009-11-03T04:00:39Z					cellular_component											owl:Class	
GO:0102963	biolink:NamedThing	(S)-corytuberine synthase activity	Catalysis of the reaction: H+ + (S)-reticulinium(1+) + NADPH + O2 <=> (S)-corytuberine + NADP + 2 H2O.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/21133			EC:1.14.19.51|MetaCyc:RXN-9314|RHEA:51540									molecular_function											owl:Class	
GO:0050125	biolink:NamedThing	N-benzyloxycarbonylglycine hydrolase activity	Catalysis of the reaction: N-benzyloxycarbonylglycine + H(2)O + H(+) = benzyl alcohol + CO(2) + glycine.	tmpzr1t_l9r_go_relaxed.owl	nalpha-carbobenzoxyamino acid amidohydrolase activity|N-benzyloxycarbonylglycine urethanehydrolase activity|nalpha-benzyloxycarbonyl amino acid urethane hydrolase activity|nalpha-benzyloxycarbonyl amino acid urethane hydrolase I|benzyloxycarbonylglycine hydrolase activity				EC:3.5.1.58|MetaCyc:N-BENZYLOXYCARBONYLGLYCINE-HYDROLASE-RXN|KEGG_REACTION:R02551|RHEA:20900									molecular_function											owl:Class	
GO:0047163	biolink:NamedThing	3,4-dichloroaniline N-malonyltransferase activity	Catalysis of the reaction: 3,4-dichloroaniline + malonyl-CoA = N-(3,4-dichlorophenyl)malonamate + CoA.	tmpzr1t_l9r_go_relaxed.owl	malonyl-CoA:3,4-dichloroaniline N-malonyltransferase activity				MetaCyc:2.3.1.114-RXN|RHEA:21060|EC:2.3.1.114|KEGG_REACTION:R04050									molecular_function											owl:Class	
GO:0031892	biolink:NamedThing	type 2 vasoactive intestinal polypeptide receptor binding	Binding to a type 2 vasoactive intestinal polypeptide receptor.	tmpzr1t_l9r_go_relaxed.owl	type 3 PACAP receptor binding|type 2 vasoactive intestinal polypeptide receptor ligand													molecular_function											owl:Class	
GO:0102243	biolink:NamedThing	ATP:geranylgeraniol phosphotransferase activity	Catalysis of the reaction: (E,E)-geranylgeraniol + ATP = H+ + all-trans-geranyl-geranyl monophosphate + ADP.	tmpzr1t_l9r_go_relaxed.owl					EC:2.7.1.216|MetaCyc:RXN-12325|RHEA:61660									molecular_function											owl:Class	
GO:0039679	biolink:NamedThing	viral occlusion body	A crystalline protein matrix surrounding the nucleocapsids of some insect viruses after their release in the environment. Produced in the host cell, the occlusion body protects the infectious virion after death of the host.	tmpzr1t_l9r_go_relaxed.owl					VZ:1949			bf	2013-09-26T14:17:10Z					cellular_component											owl:Class	
GO:0102913	biolink:NamedThing	3-aminomethylindole N-methyltransferase activity	Catalysis of the reaction: indol-3-ylmethylamine + S-adenosyl-L-methionine  = H+ + N-methyl-3-aminomethylindole + S-adenosyl-L-homocysteine.	tmpzr1t_l9r_go_relaxed.owl					RHEA:52268|MetaCyc:RXN-8686									molecular_function											owl:Class	
GO:0101014	biolink:NamedThing	[isocitrate dehydrogenase (NADP+)] phosphatase activity	Catalysis of the reaction: [isocitrate dehydrogenase] phosphate + H2O = [isocitrate dehydrogenase] + phosphate.	tmpzr1t_l9r_go_relaxed.owl	isocitrate dehydrogenase kinase/phosphatase activity				MetaCyc:ICITDEHASE-KIN-PHOSPHA									molecular_function											owl:Class	
GO:0047505	biolink:NamedThing	(-)-menthol monooxygenase activity	Catalysis of the reaction: (-)-menthol + H(+) + NADPH + O(2) = 1,4-menthane-3,8-diol + H(2)O + NADP(+).	tmpzr1t_l9r_go_relaxed.owl	l-menthol monooxygenase activity|(-)-menthol,NADPH:oxygen oxidoreductase (8-hydroxylating)				EC:1.14.13.46|RHEA:11648|MetaCyc:--MENTHOL-MONOOXYGENASE-RXN|KEGG_REACTION:R02178									molecular_function											owl:Class	
GO:0060780	biolink:NamedThing	intercalary leaflet morphogenesis	The process in which the intercalary leaflet attains its shape. An intercalary leaflet is a leaflet that develops between primary leaflets.	tmpzr1t_l9r_go_relaxed.owl								dph	2009-07-25T07:20:46Z					biological_process											owl:Class	
GO:0018543	biolink:NamedThing	4-amino-2-nitroso-6-nitrotoluene reductase activity	Catalysis of the reaction: 4-amino-2-hydroxylamino-6-nitrotoluene + NADP+ = NADPH + H+ + 4-amino-2-nitroso-6-nitrotoluene.	tmpzr1t_l9r_go_relaxed.owl					UM-BBD_reactionID:r0464									molecular_function											owl:Class	
GO:0048105	biolink:NamedThing	establishment of body hair planar orientation	Orientation of body hairs, projections from the surface of an organism, such that the hairs all point in a uniform direction along the surface.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0050091	biolink:NamedThing	melilotate 3-monooxygenase activity	Catalysis of the reaction: 3-(2-hydroxyphenyl)propanoate + H(+) + NADH + O(2) = 3-(2,3-dihydroxyphenyl)propanoate + H(2)O + NAD(+).	tmpzr1t_l9r_go_relaxed.owl	melilotate hydroxylase activity|3-(2-hydroxyphenyl)propanoate,NADH:oxygen oxidoreductase (3-hydroxylating)|melilotic hydroxylase activity|2-hydroxyphenylpropionic hydroxylase activity|2-hydroxyphenylpropionate hydroxylase activity				EC:1.14.13.4|MetaCyc:MELILOTATE-3-MONOOXYGENASE-RXN|RHEA:17669|KEGG_REACTION:R03369									molecular_function											owl:Class	
GO:0050139	biolink:NamedThing	nicotinate-N-glucosyltransferase activity	Catalysis of the reaction: nicotinate + UDP-D-glucose = N-(beta-D-glucosyl)nicotinate + UDP.	tmpzr1t_l9r_go_relaxed.owl	nicotinate glucosyltransferase activity|UDP-glucose:nicotinate N-glucosyltransferase activity|UDPglucose:nicotinate N-glucosyltransferase activity|UDP-glucose:nicotinic acid-N-glucosyltransferase activity|uridine diphosphoglucose-nicotinate N-glucosyltransferase activity				MetaCyc:NICOTINATE-GLUCOSYLTRANSFERASE-RXN|RHEA:19437|KEGG_REACTION:R01722|EC:2.4.1.196									molecular_function											owl:Class	
GO:0018557	biolink:NamedThing	1,2-dihydroxyfluorene 1,1-alpha-dioxygenase activity	Catalysis of the reaction: 1,2-dihydroxyfluorene + O2 = 2-hydroxy-4-(2-oxo-1,3-dihydro-2H-inden-1-ylidene) but-2-enoic acid.	tmpzr1t_l9r_go_relaxed.owl					EC:1.13.11.-|UM-BBD_reactionID:r0422									molecular_function											owl:Class	
GO:0102589	biolink:NamedThing	cyanidin 3-O-glucoside 3'',6''-O-dimalonyltransferase activity	Catalysis of the reaction: cyanidin 3-O-(6-O-malonyl-beta-D-glucoside) + malonyl-CoA(5-) <=> cyanidin 3-O-(3''', 6''-O-dimalonyl-beta-glucopyranoside) + coenzyme A.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:RXN-15336									molecular_function											owl:Class	
GO:0032295	biolink:NamedThing	ensheathment of neuronal cell bodies	The process in which satellite glial cells isolate neuronal cell bodies.	tmpzr1t_l9r_go_relaxed.owl														biological_process											owl:Class	
GO:0102219	biolink:NamedThing	phosphogluco-amylopectin water dikinase activity	Catalysis of the reaction: n ATP + n H2O + a 6-phosphogluco-amylopectin = n AMP + n hydrogenphosphate + a 6-phosphogluco-3-phosphogluco-amylopectin.	tmpzr1t_l9r_go_relaxed.owl					EC:2.7.9.5|MetaCyc:RXN-12204									molecular_function											owl:Class	
GO:0052660	biolink:NamedThing	R-lactaldehyde reductase activity	Catalysis of the reaction: (R)-propane-1,2-diol + NAD+ = (R)-lactaldehyde + NADH + H+.	tmpzr1t_l9r_go_relaxed.owl	D-lactaldehyde:propanediol oxidoreductase activity|(R)-propane-1,2-diol:NAD+ oxidoreductase activity				KEGG_REACTION:R03080|RHEA:23872|MetaCyc:RXN-8641									molecular_function											owl:Class	
GO:1990175	biolink:NamedThing	EH domain binding	Binding to an EH domain of a protein. The EH stand for Eps15 homology. This was originally identified as a motif present in three copies at the NH2-termini of Eps15 and of the related molecule Eps15R.	tmpzr1t_l9r_go_relaxed.owl								hjd	2013-08-27T20:14:56Z					molecular_function											owl:Class	
GO:0106173	biolink:NamedThing	COPII-coated vesicle lumen	The volume enclosed by the membrane of a COPII-coated endocytic vesicle.	tmpzr1t_l9r_go_relaxed.owl								hjd	2019-02-11T18:16:22Z					cellular_component											owl:Class	
GO:0034685	biolink:NamedThing	integrin alphav-beta6 complex	An integrin complex that comprises one alphav subunit and one beta6 subunit.	tmpzr1t_l9r_go_relaxed.owl	alphav-beta6 integrin complex|ITGAV-ITGB6 complex													cellular_component											owl:Class	
GO:1990325	biolink:NamedThing	collagen type XXVII trimer	A collagen homotrimer of alpha1(XXVII) chains. These trimers form thin, non-striated fibrils. Type XXVII collagen triple helices play a role during the calcification of cartilage and the transition of cartilage to bone.	tmpzr1t_l9r_go_relaxed.owl								bhm	2014-03-16T23:13:15Z					cellular_component											owl:Class	
GO:0047458	biolink:NamedThing	beta-pyrazolylalanine synthase activity	Catalysis of the reaction: O-acetyl-L-serine + pyrazole = 3-(pyrazol-1-yl)-L-alanine + acetate + H(+).	tmpzr1t_l9r_go_relaxed.owl	O3-acetyl-L-serine:pyrazole 1-(2-amino-2-carboxyethyl)transferase activity|BPA-synthase activity|pyrazolylalaninase activity|beta-pyrazolylalanine synthase (acetylserine) activity|beta-(1-pyrazolyl)alanine synthase activity|O(3)-acetyl-L-serine acetate-lyase (adding pyrazole) activity|O3-acetyl-L-serine acetate-lyase (adding pyrazole)|3-O-acetyl-L-serine:pyrazole 1-(2-amino-2-carboxyethyl)transferase activity|pyrazolealanine synthase activity|beta-pyrazolealanine synthase activity				RHEA:13117|MetaCyc:2.5.1.51-RXN|EC:2.5.1.51|KEGG_REACTION:R03134									molecular_function											owl:Class	
RO:0002092	biolink:NamedThing	happens during		tmpzr1t_l9r_go_relaxed.owl					RO:0002092|RO:0002092									external|external									happens_during|happens_during		owl:ObjectProperty	
RO:0002093	biolink:NamedThing	ends_during		tmpzr1t_l9r_go_relaxed.owl					RO:0002093|RO:0002093									external|external									ends_during|ends_during		owl:ObjectProperty	
BFO:0000050	biolink:NamedThing	part of		tmpzr1t_l9r_go_relaxed.owl					BFO:0000050|BFO:0000050									external|external									part_of|part_of		owl:ObjectProperty	
BFO:0000051	biolink:NamedThing	has part		tmpzr1t_l9r_go_relaxed.owl					BFO:0000051|BFO:0000051									external|external									has_part|has_part		owl:TransitiveProperty	
RO:0002213	biolink:NamedThing	positively regulates		tmpzr1t_l9r_go_relaxed.owl					RO:0002213|RO:0002213									external|external									positively_regulates|positively_regulates		owl:ObjectProperty	
regulates	biolink:NamedThing	regulates		tmpzr1t_l9r_go_relaxed.owl					RO:0002211|RO:0002211									external|external									regulates|regulates		owl:TransitiveProperty	
RO:0002212	biolink:NamedThing	negatively regulates		tmpzr1t_l9r_go_relaxed.owl					RO:0002212|RO:0002212									external|external									negatively_regulates|negatively_regulates		owl:ObjectProperty	
GO:0010708	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0048062	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
IAO:0000227	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl																										
GO:1902505	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0072424	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0019947	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GOP:goslim_synapse	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl						synapse GO slim																			owl:AnnotationProperty	
GOP:gocheck_do_not_annotate	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl						Term not to be used for direct annotation																			owl:AnnotationProperty	
NCBITaxon:8782	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl																										
GO:1904834	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0044253	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0044287	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0044368	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GOP:goslim_drosophila	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl						Drosophila GO slim																			owl:AnnotationProperty	
GO:0001592	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1903827	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1904822	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0006136	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0042114	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0072650	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0046735	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GOP:goslim_generic	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl						Generic GO slim																			owl:AnnotationProperty	
GO:0008624	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052459	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:2000778	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GOP:goslim_candida	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl						Candida GO slim																			owl:AnnotationProperty	
GO:0000371	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
NCBITaxon:3312	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl																										
GOP:goslim_metagenomics	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl						Metagenomics GO slim																			owl:AnnotationProperty	
GO:0019591	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0007332	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GOP:gocheck_do_not_manually_annotate	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl						Term not to be used for direct manual annotation																			owl:AnnotationProperty	
GO:0052552	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045086	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
NCBITaxon:33208	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl																										
GO:0042738	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0031678	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0030090	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0003710	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0150134	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0001948	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0055033	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052483	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0033587	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0019130	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GOP:goslim_pir	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl						PIR GO slim																			owl:AnnotationProperty	
GO:0003280	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0048178	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
NCBITaxon:4751	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl																										
NCBITaxon:33090	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl																										
GO:0052669	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0002219	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0004006	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0003936	biolink:NamedThing	obsolete hydrogen-transporting two-sector ATPase activity	OBSOLETE. Catalysis of the reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out).	tmpzr1t_l9r_go_relaxed.owl	proton-transporting two-sector ATPase activity|hydrogen-transporting two-sector ATPase activity					This term was made obsolete because it refers to a bifunctional gene product.	GO:0046961|GO:0046933				True	GO:0004006|GO:0008729		molecular_function											owl:Class	
GO:1990291	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1990335	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045424	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052302	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
NCBITaxon:2759	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl																										
GO:0042237	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0001513	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0042235	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0030453	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0051488	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0007226	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0047607	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1990290	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0072483	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045536	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0008185	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0048125	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0072456	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0043238	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045308	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GOP:goslim_plant	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl						Plant GO slim																			owl:AnnotationProperty	
GO:0010687	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045375	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0090466	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0071147	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1902470	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045941	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0042107	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0008326	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0038005	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045409	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0044755	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0022814	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0044810	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0006332	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0009680	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0018176	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015788	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016974	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0032403	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045358	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0033817	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0072622	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0042916	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0046698	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GOP:goslim_chembl	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl						ChEMBL protein targets summary																			owl:AnnotationProperty	
GO:0032519	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045531	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0072405	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0031186	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1904454	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0050327	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0072404	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1901243	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:2000667	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0090526	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0004811	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0051533	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0051226	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0048113	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0051532	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0009031	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GOP:goslim_aspergillus	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl						Aspergillus GO slim																			owl:AnnotationProperty	
NCBITaxon:9443	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl																										
GO:0008646	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0017047	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0030407	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0000508	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0008729	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0043072	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0033205	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0072543	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0071956	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015285	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0061636	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0032192	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1901042	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0048234	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0003890	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0098707	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0004094	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016693	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0018918	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015238	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0002741	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0006834	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0071157	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0085028	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1903400	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GOP:goslim_yeast	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl						Yeast GO slim																			owl:AnnotationProperty	
GO:0042524	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
NCBITaxon:6656	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl																										
GO:0072455	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016000	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0072612	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1905078	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0044446	biolink:NamedThing	obsolete intracellular organelle part	OBSOLETE. A constituent part of an intracellular organelle, an organized structure of distinctive morphology and function, occurring within the cell. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton but excludes the plasma membrane.	tmpzr1t_l9r_go_relaxed.owl						Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.	GO:0043229				True			cellular_component											owl:Class	
GO:0018380	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0031794	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0051833	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016978	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0032861	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0044705	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045502	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0017091	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0043118	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0005752	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0005361	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052292	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052109	biolink:NamedThing	obsolete induction by symbiont of defense-related host cell wall callose deposition	OBSOLETE. Any process in which an organism activates, maintains or increases the frequency, rate or extent of the deposition of callose by the host in its cell walls, occurring as part of the defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	positive regulation by symbiont of defense-related host callose deposition|up-regulation by symbiont of defense-related host cell wall callose deposition|positive regulation by symbiont of defense-related host cell wall callose deposition|activation by symbiont of defense-related host cell wall callose deposition|upregulation by symbiont of defense-related host cell wall callose deposition|positive regulation by organism of defense-related callose deposition in other organism involved in symbiotic interaction|positive regulation by organism of defense-related cell wall callose deposition in other organism involved in symbiotic interaction|stimulation by symbiont of defense-related host cell wall callose deposition|up regulation by symbiont of defense-related host cell wall callose deposition					This term was obsoleted because it is a host, not a symbiont process, but was formulated as a symbiont process.					True	GO:0052291|GO:0052107|GO:0052292		biological_process											owl:Class	
GO:0007184	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0009286	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0048157	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045370	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0036282	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0004093	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0003287	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0072457	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0072400	biolink:NamedThing	obsolete detection of stimulus involved in mitotic DNA integrity checkpoint	OBSOLETE. The series of events in which information about DNA integrity is received and converted into a molecular signal, contributing to a mitotic DNA integrity checkpoint.	tmpzr1t_l9r_go_relaxed.owl	DNA integrity checkpoint sensor mechanism|detection of stimulus involved in mitotic G2/M transition decatenation checkpoint|DNA integrity checkpoint sensor process|sensing involved in DNA integrity checkpoint|mitotic G2/M transition decatenation checkpoint sensor mechanism|sensing involved in mitotic G2/M transition decatenation checkpoint|mitotic G2/M transition decatenation checkpoint sensor process	https://github.com/geneontology/go-ontology/issues/20976				This term was obsoleted because it corresponds to a molecular function.		mah	2010-12-08T03:29:11Z		True	GO:0072457		biological_process											owl:Class	
GO:0045376	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0043081	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
NCBITaxon:4896	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl																										
GO:0005578	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0075124	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0010300	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0001668	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GOP:goslim_agr	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl						AGR slim																			owl:AnnotationProperty	
GO:0002642	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052296	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052157	biolink:NamedThing	obsolete modulation by symbiont of microbe-associated molecular pattern-induced host innate immune response	OBSOLETE. Any process that involves recognition of a microbe-associated molecular pattern, and by which a symbiont modulates the frequency, rate or extent of the innate immune response of the host organism; the innate immune response is the host's first line of defense against infection. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	modulation by symbiont of pathogen-associated molecular pattern-induced host innate immunity|modulation by symbiont of microbe-associated molecular pattern-induced host innate immunity|modulation by organism of microbe-associated molecular pattern-induced innate immune response in other organism involved in symbiotic interaction	https://github.com/geneontology/go-ontology/issues/18808				The reason for obsoletion is that this term has been misused.					True	GO:0052296		biological_process											owl:Class	
GO:0009043	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0030469	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0050475	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0018605	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016949	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0048154	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0001127	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0004678	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0031183	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0043351	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052261	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1902861	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0075706	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0050711	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0070632	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0032846	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0042502	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0051023	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045166	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0008383	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0048420	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0018017	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016547	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0048418	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0043146	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0000397	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0032514	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0006394	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0048051	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045530	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0150130	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0033224	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0008599	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0035068	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0005084	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0005644	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0042232	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0000356	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0001610	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0032842	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0018994	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0005325	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016599	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0044783	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0008536	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015071	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0043206	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0097369	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1901368	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0050718	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045073	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0051376	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GOP:goslim_flybase_ribbon	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl						FlyBase Drosophila GO ribbon slim																			owl:AnnotationProperty	
OIO:SubsetProperty	biolink:NamedThing	subset_property		tmpzr1t_l9r_go_relaxed.owl																									owl:AnnotationProperty	
GO:0019421	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0009430	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0051829	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0044410	biolink:NamedThing	obsolete entry into host through natural portals	OBSOLETE. Penetration by a symbiont into a host organism via naturally occurring openings in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	entry into other organism through natural portals involved in symbiotic interaction|entry into other organism through natural portals during symbiotic interaction					This is an unnecessary grouping term.					True	GO:0051829		biological_process											owl:Class	
GO:0007025	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0023033	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0102022	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052555	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0035030	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0001789	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0019733	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0001645	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015569	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1900479	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045389	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0031194	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GOP:goslim_pombe	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl						Fission yeast GO slim																			owl:AnnotationProperty	
GO:0020034	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0009456	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0048220	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0150121	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0098612	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0000361	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045432	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0046954	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0008382	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0042223	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
NCBITaxon:4890	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl																										
GO:0052099	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0043026	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0005636	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016957	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0007013	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0051277	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0017048	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0004975	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0004041	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016425	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0048474	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0042233	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0006737	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0060145	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0071856	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0050726	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1904623	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0120081	biolink:NamedThing	obsolete positive regulation of microfilament motor activity	OBSOLETE. Any process that activates or increases the frequency, rate or extent of microfilament motor activity.	tmpzr1t_l9r_go_relaxed.owl	activation of actin-dependent ATPase activity|positive regulation of actin-filament motor activity|positive regulation of actin-activated ATPase activity|upregulation of actin-dependent ATPase activity|activation of actin-activated ATPase activity|positive regulation of muscle motor activity|positive regulation of actin filament motor activity|positive regulation of myosin ATPase activity|positive regulation of actin-dependent ATPase activity	https://github.com/geneontology/go-ontology/issues/20877|https://github.com/geneontology/go-ontology/issues/21626				This term was obsoleted because it represents a molecular function.	GO:0140660	krc	2017-07-05T21:48:56Z		True	GO:1904623		biological_process											owl:Class	
GO:0003748	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0044112	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0001143	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1990292	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0051314	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0038125	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016961	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0004785	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052260	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0047340	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0003736	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GOP:goslim_mouse	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl						Mouse GO slim																			owl:AnnotationProperty	
GO:0072648	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0006908	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0032857	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015198	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1902469	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0005069	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0019952	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0046749	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0046472	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0042282	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0099132	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0000499	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0071804	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
NCBITaxon:5782	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl																										
GO:0001204	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0071777	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0097724	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045385	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0002641	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0032320	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0061018	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0043735	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0075060	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015270	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1902582	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0010554	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0042090	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1903261	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0051372	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0042525	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015302	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0008577	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015595	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0044115	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0008698	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016548	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045415	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1900042	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0009818	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0030362	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0019851	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0005390	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0018696	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0075129	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0044121	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0090099	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0010163	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0046763	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0051487	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045405	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016786	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0072454	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0072412	biolink:NamedThing	obsolete detection of stimulus involved in mitotic cell cycle checkpoint	OBSOLETE. The series of events in which information about a biological process or quality is received and converted into a molecular signal, contributing to a mitotic cell cycle checkpoint.	tmpzr1t_l9r_go_relaxed.owl	mitotic cell cycle G1/S checkpoint sensor mechanism|sensing involved in mitotic cell cycle G1/S checkpoint|detection of stimulus involved in mitotic cell cycle G1/S checkpoint|mitotic cell cycle checkpoint sensor mechanism|mitotic cell cycle checkpoint sensor process|mitotic cell cycle G1/S checkpoint sensor process|sensing involved in mitotic cell cycle checkpoint	https://github.com/geneontology/go-ontology/issues/20976				This term was obsoleted because it corresponds to a molecular function.		mah	2010-12-08T03:48:57Z		True	GO:0072472|GO:0072454		biological_process											owl:Class	
GO:0015354	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0098805	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0036329	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0008151	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0039591	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0008896	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0018383	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052433	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0001102	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045363	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0022895	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0050895	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016588	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0072473	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045946	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0006317	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0046764	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0032569	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0032520	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045556	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
NCBITaxon:3176	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl																										
GO:0072616	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052044	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016193	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045378	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1902096	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0072603	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0150132	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0071776	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0000134	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0043360	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0004116	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1902303	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0120018	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1990041	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0030138	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1990122	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0001215	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0008739	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0018917	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045085	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0075006	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0043689	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0001611	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0044822	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0004752	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0070869	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0072446	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0046616	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0044404	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0009623	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0010861	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0019138	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0008778	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0007513	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1902504	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0017132	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1901688	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0031575	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0048131	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0042606	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0042570	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0043390	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0001146	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015273	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015781	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1904207	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0061500	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0001145	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
NCBITaxon:4932	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl																										
GO:0045411	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0085031	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0006444	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0035084	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0102316	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0044457	biolink:NamedThing	obsolete cell septum part	OBSOLETE. Any constituent part of a cell septum, a structure composed of peptidoglycan and often chitin in addition to other materials. It usually forms perpendicular to the long axis of a cell or hypha and grows centripetally from the cell wall to the center of the cell and often functions in the compartmentalization of a cell into two daughter cells.	tmpzr1t_l9r_go_relaxed.owl						Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.	GO:0030428				True			cellular_component											owl:Class	
GO:0052253	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0008325	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0004695	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0006736	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0044125	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052565	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052297	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0001166	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0060881	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052272	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0030475	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0009814	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0051772	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0060564	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0001212	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0001612	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0003761	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0003754	biolink:NamedThing	obsolete chaperone activity	OBSOLETE. Assists in the correct non-covalent assembly of polypeptide-containing structures in vivo, but is not a component of these assembled structures when they are performing their normal biological function.	tmpzr1t_l9r_go_relaxed.owl	chaperone activity					This term was made obsolete because, as defined, it represents a class of gene products rather than a molecular function. The term string is also ambiguous, having connotations of involvement in transport processes.	GO:0006457|GO:0051082|GO:0044183				True	GO:0003758|GO:0003757|GO:0003761|GO:0003760		molecular_function											owl:Class	
GO:0010261	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0009993	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0043358	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0001901	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052936	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1990421	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0006456	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0005286	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0008621	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0065006	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0002245	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0044767	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0051809	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0000501	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052294	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0042112	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0033680	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0031677	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016359	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0072642	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0072610	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0042517	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0007024	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0010963	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045076	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0042917	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016022	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0001624	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0004562	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052107	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
NCBITaxon:2	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl																										
GO:0070364	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045364	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0140079	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0044461	biolink:NamedThing	obsolete bacterial-type flagellum part	OBSOLETE. Any constituent part of the bacterial-type flagellum, a 20 nm diameter filament composed of subunits of flagellin driven passively at its base by a motor powered by a transmembrane ion potential, typically a proton or sodium potential.	tmpzr1t_l9r_go_relaxed.owl	flagellin-based flagellum part					Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.	GO:0009288				True			cellular_component											owl:Class	
GO:0010010	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0002226	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0008244	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016066	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0097405	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0030376	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0005279	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0000928	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045878	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0043092	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015682	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0008122	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0000037	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0001020	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0032583	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0032134	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0007177	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045400	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015022	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
NCBITaxon:4895	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl																										
GO:0051807	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0023045	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016439	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052273	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0030676	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0072607	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0030480	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052300	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0000980	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045527	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052275	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052286	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015237	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GOP:systematic_synonym	biolink:NamedThing	Systematic synonym		tmpzr1t_l9r_go_relaxed.owl																									owl:AnnotationProperty	
OIO:SynonymTypeProperty	biolink:NamedThing	synonym_type_property		tmpzr1t_l9r_go_relaxed.owl																									owl:AnnotationProperty	
GO:0019004	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0009054	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0000997	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0046781	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0075140	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0008101	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1902741	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0003703	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0080138	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045555	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0044744	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0019968	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0000360	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0072620	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0000065	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0044661	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0060181	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0006467	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0072519	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0080039	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0034989	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0043089	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0004296	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0010577	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0150131	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0008578	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0075123	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0042519	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0007061	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0018797	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0042527	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0072420	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0019052	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015497	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0031046	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0007326	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0032582	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0043492	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016930	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0070361	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
NCBITaxon:147554	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl																										
GO:0015992	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0034600	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0072509	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0048411	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016991	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0043869	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0005349	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0072434	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0004403	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0031791	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0035414	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0072447	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015357	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0018018	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0051773	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0006159	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0048547	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0009282	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0070751	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0008262	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015907	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0043357	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0005299	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0042506	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0035972	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052263	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052550	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052413	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0042384	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0007408	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0007047	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0008280	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0030918	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0033287	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0042623	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0030722	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0071843	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0031373	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0003770	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0060150	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0043241	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045367	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0018374	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0006320	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0042024	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016932	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0006095	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0150170	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0008491	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1990285	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0007092	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0044811	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0051708	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0051813	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1902591	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0006008	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0048470	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0000163	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0005529	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0102017	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0102026	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0017112	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0043389	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045810	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045382	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0006645	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0042528	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0071146	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0006745	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0061039	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0048005	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0007514	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045426	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0048558	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015542	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0044243	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0042569	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0004220	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0003891	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0042095	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0044746	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045406	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045410	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016455	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0102908	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0023032	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0048423	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0040023	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0061490	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0018999	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015008	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0150126	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0046743	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0044454	biolink:NamedThing	obsolete nuclear chromosome part	OBSOLETE. Any constituent part of a nuclear chromosome, a chromosome that encodes the nuclear genome and is found in the nucleus of a eukaryotic cell during the cell cycle phases when the nucleus is intact.	tmpzr1t_l9r_go_relaxed.owl						Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.	GO:0000228				True			cellular_component											owl:Class	
GO:0004280	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0010993	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0032503	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016350	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0071974	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0072606	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0048747	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0031971	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016431	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045534	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015604	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0070362	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052513	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045539	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0097617	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0010802	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0003826	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0103051	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0010740	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1902825	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0072323	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0032779	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0003758	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0048187	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1902368	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0033279	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0003771	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0036442	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0030306	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0080063	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0071145	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0034459	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0042607	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0001036	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0008006	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0005973	biolink:NamedThing	obsolete fibrinogen beta chain	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	fibrinogen beta chain					This term was made obsolete because it represents a single gene product and not a complex.	GO:0005577				True	GO:0008006		cellular_component											owl:Class	
GO:0043298	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1902094	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0002392	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045537	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0004841	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0035468	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045083	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0043440	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1902479	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0031007	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0042238	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1990367	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0048116	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0000013	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0000008	biolink:NamedThing	obsolete thioredoxin	OBSOLETE. A small disulfide-containing redox protein that serves as a general protein disulfide oxidoreductase. Interacts with a broad range of proteins by a redox mechanism, based on the reversible oxidation of 2 cysteine thiol groups to a disulfide, accompanied by the transfer of 2 electrons and 2 protons. The net result is the covalent interconversion of a disulfide and a dithiol.	tmpzr1t_l9r_go_relaxed.owl	thioredoxin					This term was made obsolete because it represents gene products.	GO:0015036|GO:0003756				True	GO:0000013		molecular_function											owl:Class	
GO:0072644	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016686	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0051529	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045074	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0010302	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016948	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0070970	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0004761	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0005620	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0048603	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015555	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0050703	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0030702	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0031292	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0036229	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0033613	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052456	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052567	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015222	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0071151	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
NCBITaxon:28009	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl																										
GO:0043019	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0001024	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:2001048	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0048177	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
NCBITaxon:Union_0000023	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl																										
GO:0001224	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0031793	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0032893	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0046953	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1901677	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0060356	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016522	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0018790	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0030606	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0030764	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0048043	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0090702	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0048416	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
NCBITaxon:2157	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl																										
GO:0016609	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0000941	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0008669	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0001038	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0001004	biolink:NamedThing	obsolete RNA polymerase III transcription regulator recruiting activity	OBSOLETE. Initiating the assembly of the RNA polymerase III pre-initiation complex by binding to a control sequence in the intragenic region. This allows to recruit TFIIIB to the DNA at a site centered approximately 26 base pairs upstream of the start site of transcription. For tRNA genes, TFIIIC first associates with DNA, and then recruits TFIIIB. For 5S rRNA genes, TFIIIA binds to DNA first, followed by TFIIIC, which then recruits TFIIIB.	tmpzr1t_l9r_go_relaxed.owl	transcription factor activity, RNA polymerase III type 3 promoter TFIIIB recruiting|transcription factor activity, RNA polymerase III type 1 promoter sequence-specific binding, TFIIIB recruiting|RNA polymerase III type 3 promoter TFIIIB recruiting transcription factor activity|RNA polymerase III promoter sequence-specific DNA binding TFIIIB recruiting transcription factor activity|TFIIIA activity|type 3 RNA polymerase III promoter recognition|RNA polymerase III hybrid type promoter TFIIIB recruiting transcription factor activity|RNA polymerase III assembly factor activity, TFIIIB recruiting|transcription factor activity, RNA polymerase III type 1 promoter TFIIIB|transcription factor activity, RNA polymerase III promoter sequence-specific binding, TFIIIB recruiting|RNA polymerase III assembly factor activity|type 2 RNA polymerase III promoter recognition|TFIIIC-type activity|transcription factor activity, RNA polymerase III type 2 promoter sequence-specific binding, TFIIIB recruiting|RNA polymerase III type 1 promoter sequence-specific DNA binding TFIIIB recruiting transcription factor activity|RNA polymerase III transcription factor recruiting activity|SNAPc-type activity|RNA polymerase III type 2 promoter sequence-specific DNA binding TFIIIB recruiting transcription factor activity	https://github.com/geneontology/go-ontology/issues/14852|https://github.com/geneontology/go-ontology/issues/18561				The reason for obsoletion is that this function is redundant with other terms, most often 'transcription co-regulator activity; GO:0003712'.		krc	2010-08-18T05:53:32Z		True	GO:0001033|GO:0001038|GO:0001005|GO:0001157|GO:0001008		molecular_function											owl:Class	
GO:0150171	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0051739	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0032568	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1902402	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016179	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0002739	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0042504	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015242	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0044401	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1902826	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0060403	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016214	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015458	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0007335	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1901139	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0085027	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0000251	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016952	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0000734	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0042493	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045126	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0061020	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0018093	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0035413	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045673	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0035690	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0043148	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0044757	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0042485	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0048118	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0043070	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0006454	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0031512	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0006899	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0006994	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0005679	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016585	biolink:NamedThing	obsolete chromatin remodeling complex	OBSOLETE. Any complex that mediates dynamic changes in eukaryotic chromatin.	tmpzr1t_l9r_go_relaxed.owl	chromatin remodelling complex|nucleosome remodeling complex|chromatin remodeling complex					This term was made obsolete because its definition no longer reflects and cannot be modified to be consistent with the current state of knowledge.	GO:0006338				True	GO:0005679		cellular_component											owl:Class	
GO:0031075	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045153	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0034747	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052070	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0006819	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0001620	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0080055	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1990903	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0098667	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0006092	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0000496	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0001180	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0097483	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0035057	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0023013	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016302	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
NCBITaxon:554915	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl																										
GO:0005293	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0000383	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0106287	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0044246	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0003752	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0001121	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
NCBITaxon:50557	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl																										
GO:0051576	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0036144	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1990237	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0072395	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0031199	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0001747	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0004404	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0036326	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0034742	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0007148	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016190	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1902506	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0046788	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0043140	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0072512	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0061023	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0008524	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0039538	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015365	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0030396	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0046795	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0032575	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0004804	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0001140	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0031909	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0048119	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0051706	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0051704	biolink:NamedThing	obsolete multi-organism process	OBSOLETE. A biological process which involves another organism of the same or different species.	tmpzr1t_l9r_go_relaxed.owl	physiological interaction between organisms|physiological interaction with other organism|interaction between organisms	https://github.com/geneontology/go-ontology/issues/21459				This term was obsoleted because it was not a biologically meaningful grouping class.					True	GO:0051706		biological_process											owl:Class	
GO:0001157	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052932	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0050752	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1905185	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0018055	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1901912	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0006944	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:2000600	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1902589	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0010382	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052469	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0090530	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0003888	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0080137	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1905076	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0018236	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0000167	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045285	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0042936	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052307	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0010655	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0055027	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0009564	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0048425	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0008054	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052279	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0099133	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0001719	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0006831	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0001138	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0001135	biolink:NamedThing	obsolete RNA polymerase II transcription regulator recruiting activity	OBSOLETE. The function of binding to an RNA polymerase II (RNAP II) transcription regulator and recruiting it to the general transcription machinery complex in order to modulate transcription initiation.	tmpzr1t_l9r_go_relaxed.owl	TFIIE-class transcription factor recruiting transcription factor activity|transcription factor activity, TFIIF-class transcription factor recruiting|TFIIH-class transcription factor recruiting transcription factor activity|RNA polymerase II transcription factor recruiting transcription factor activity|RNA polymerase II transcription factor recruiting activity|transcription factor activity, TFIIE-class transcription factor recruiting|transcription factor activity, TFIIH-class transcription factor recruiting|transcription factor activity, RNA polymerase II transcription factor recruiting|TFIIF-class transcription factor recruiting transcription factor activity	https://github.com/geneontology/go-ontology/issues/15795|https://github.com/geneontology/go-ontology/issues/18561		GO:0003712		The reason for obsoletion is that this function is redundant with other terms, most often 'transcription co-regulator activity; GO:0003712'.		krc	2011-01-20T05:13:12Z		True	GO:0001138|GO:0001137|GO:0001136		molecular_function											owl:Class	
GO:0010502	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0044463	biolink:NamedThing	obsolete cell projection part	OBSOLETE. Any constituent part of a cell projection, a prolongation or process extending from a cell, e.g. a flagellum or axon.	tmpzr1t_l9r_go_relaxed.owl						Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.	GO:0042995				True			cellular_component											owl:Class	
GO:0097458	biolink:NamedThing	obsolete neuron part	OBSOLETE. Any constituent part of a neuron, the basic cellular unit of nervous tissue. A typical neuron consists of a cell body (often called the soma), an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the nervous system.	tmpzr1t_l9r_go_relaxed.owl							CL:0000540	pr	2012-12-19T16:53:50Z		True			cellular_component											owl:Class	
NCBITaxon:4930	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl																										
GO:2000505	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0006632	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0005807	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0042111	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0030236	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0042512	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0099090	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0019587	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0072556	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0061839	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016140	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0018468	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052445	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1902598	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1905950	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0090699	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0097406	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045279	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0031742	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0001125	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0036079	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0030871	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0097425	biolink:NamedThing	obsolete smooth endoplasmic reticulum part	OBSOLETE. Any constituent part of the smooth endoplasmic reticulum (also called smooth ER, or SER).	tmpzr1t_l9r_go_relaxed.owl	SER subcomponent				NIF_Subcellular:sao184202831	Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.	GO:0005790	pr	2012-11-07T13:45:14Z		True			cellular_component											owl:Class	
GO:0001021	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052303	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
NCBITaxon:4891	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl																										
GO:0043350	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045368	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016526	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0043986	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1990287	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016983	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0060733	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0009857	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0007511	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1902587	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0031790	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1903128	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045081	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0047987	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0042530	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0019201	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016687	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0018932	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1903717	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0030359	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0034913	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016982	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0031185	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0018735	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0043753	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0097319	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0006866	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0150154	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1900475	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016292	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0008555	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0018090	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016337	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0034636	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0001206	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0005101	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0006976	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0030675	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1990106	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0042089	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0036330	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0007102	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0030471	biolink:NamedThing	obsolete spindle pole body and microtubule cycle (sensu Fungi)	OBSOLETE. The dynamics of the spindle pole body and microtubule cytoskeleton during the cell cycle. Includes spindle pole body duplication and separation and formation and elongation of the mitotic spindle. As in, but not restricted to, the fungi (Fungi, ncbi_taxonomy_id:4751).	tmpzr1t_l9r_go_relaxed.owl	spindle pole body and microtubule cycle (sensu Fungi)|spindle pole body and microtubule cycle (sensu Saccharomyces)					This term was made obsolete because it has been superseded by more accurate terms to represent the biological processes occurring, and it is not clear that this term represents a useful entity.	GO:0007051|GO:0051300				True	GO:0007102		biological_process											owl:Class	
GO:0000392	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016955	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0042511	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0075127	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0031006	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0001017	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0051836	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052298	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0004537	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045373	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0003744	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0008561	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1902264	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1990373	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045526	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0042877	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0000946	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0072568	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1902714	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:2001181	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0009540	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0003996	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0050704	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0001593	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0035140	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1990337	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0038044	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0005498	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0019944	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0044765	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0030358	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0046766	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0030040	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0017155	biolink:NamedThing	obsolete sodium:hydrogen antiporter regulator activity	OBSOLETE. This term was not defined before being made obsolete.	tmpzr1t_l9r_go_relaxed.owl	sodium:hydrogen antiporter regulator activity|sodium:proton antiporter regulator					This term was made obsolete because it represents a biological process.					True	GO:0030040		molecular_function											owl:Class	
GO:0015635	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1990759	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015581	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0020017	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1902403	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0019188	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016904	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0022817	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052493	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0042033	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0006841	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0075058	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045287	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015397	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0018056	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0005336	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052000	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0042226	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0008604	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016549	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0033676	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0047314	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0075008	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0030012	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0022844	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0001131	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0090450	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0042522	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0072602	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0008003	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0046913	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045419	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0048114	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0044502	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0042460	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1902534	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045349	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0031184	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015681	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0004880	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0005097	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0008005	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1902740	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0003751	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0030344	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:2001047	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0120024	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015587	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1902538	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0030529	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1902095	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0004926	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0008522	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0000368	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0072608	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0008136	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1904622	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0120080	biolink:NamedThing	obsolete negative regulation of microfilament motor activity	OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of microfilament motor activity.	tmpzr1t_l9r_go_relaxed.owl	down regulation of actin-dependent ATPase activity|inhibition of actin-activated ATPase activity|down regulation of actin-activated ATPase activity|negative regulation of actin-dependent ATPase activity|negative regulation of myosin ATPase activity|inhibition of actin-dependent ATPase activity|negative regulation of actin filament motor activity|negative regulation of actin-filament motor activity|negative regulation of muscle motor activity|negative regulation of actin-activated ATPase activity	https://github.com/geneontology/go-ontology/issues/20877|https://github.com/geneontology/go-ontology/issues/21626				This term was obsoleted because it represents a molecular function.	GO:0140661	krc	2017-07-05T21:36:47Z		True	GO:1904622		biological_process											owl:Class	
GO:0071435	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0070890	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0020021	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0008415	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016225	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0001219	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0034047	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0031008	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0031980	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045412	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0044372	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0004091	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0055134	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0044240	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0003764	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045390	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0003698	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0009285	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0005282	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0010537	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0061461	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0090631	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015622	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0030467	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045032	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0044438	biolink:NamedThing	obsolete microbody part	OBSOLETE. Any constituent part of a microbody, a cytoplasmic organelle, spherical or oval in shape, that is bounded by a single membrane and contains oxidative enzymes, especially those utilizing hydrogen peroxide (H2O2).	tmpzr1t_l9r_go_relaxed.owl						Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.	GO:0042579				True			cellular_component											owl:Class	
GO:0016770	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0006358	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0036439	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0099600	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0032863	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0048436	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0150123	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0031212	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045078	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1903757	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0034401	biolink:NamedThing	obsolete chromatin organization involved in regulation of transcription	OBSOLETE. Any cellular process that results in the specification, formation or maintenance of the physical structure of eukaryotic chromatin that modulates the rate, frequency or extent of DNA-dependent transcription.	tmpzr1t_l9r_go_relaxed.owl	regulation of transcription from RNA polymerase II promoter, global by histone modification|activation of global transcription from RNA polymerase II promoter by histone modification|up-regulation of transcription from RNA polymerase II promoter by histone modification|establishment or maintenance of chromatin architecture during transcription|positive regulation of transcription from RNA polymerase II promoter, global by histone modification|regulation of transcription by chromatin organization|positive regulation of transcription from Pol II promoter by histone modification|activation of transcription from RNA polymerase II promoter by histone modification|stimulation of global transcription from RNA polymerase II promoter by histone modification|stimulation of transcription from RNA polymerase II promoter by histone modification|up regulation of transcription from RNA polymerase II promoter by histone modification|up regulation of global transcription from RNA polymerase II promoter by histone modification|regulation of global transcription from Pol II promoter by histone modification|positive regulation of gene-specific transcription from RNA polymerase II promoter by histone modification|positive regulation of transcription from RNA polymerase II promoter by histone modification|positive regulation of global transcription from Pol II promoter by histone modification|regulation of gene-specific transcription from RNA polymerase II promoter by histone modification|regulation of transcription from Pol II promoter by histone modification|upregulation of transcription from RNA polymerase II promoter by histone modification|upregulation of global transcription from RNA polymerase II promoter by histone modification|regulation of transcription from RNA polymerase II promoter by histone modification|up-regulation of global transcription from RNA polymerase II promoter by histone modification|regulation of transcription by chromatin organisation	https://github.com/geneontology/go-ontology/issues/22041				This term was obsoleted because these it was redundant with other terms: heterochromatin assembly and regulation of gene expression, epigenetic.		rl	2014-12-18T14:56:16Z		True	GO:1903756|GO:1903757		biological_process											owl:Class	
GO:0015037	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0043391	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0050720	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0018370	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0018384	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0072411	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1902536	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0008562	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0051534	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0075295	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0007328	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0004580	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016280	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0006917	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0019224	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0042155	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0004942	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0002005	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0072624	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052539	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052105	biolink:NamedThing	obsolete induction by symbiont of defense-related host cell wall thickening	OBSOLETE. The activation by an organism of host processes resulting in the thickening of its cell walls, occurring as part of the defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	positive regulation by symbiont of defense-related host cell wall thickening|stimulation by symbiont of defense-related host cell wall thickening|up regulation by symbiont of defense-related host cell wall thickening|activation by symbiont of defense-related host cell wall thickening|activation by organism of host defensive cell wall thickening|positive regulation by organism of defense-related cell wall thickening in other organism involved in symbiotic interaction|upregulation by symbiont of defense-related host cell wall thickening|positive regulation by organism of host defensive cell wall thickening|induction by organism of host defensive cell wall thickening|induction by organism of defense-related cell wall thickening in other organism involved in symbiotic interaction|up-regulation by symbiont of defense-related host cell wall thickening|activation by organism of defense-related host cell wall thickening					This term was obsoleted because it is a host, not a symbiont process, but was formulated as a symbiont process.					True	GO:0052538|GO:0052290|GO:0052539		biological_process											owl:Class	
NCBITaxon:241407	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl																										
GO:0044442	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0044441	biolink:NamedThing	obsolete ciliary part	OBSOLETE. Any constituent part of a cilium, a specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic (plasma) membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole.	tmpzr1t_l9r_go_relaxed.owl	cilium part|flagellum part|cilial part|flagellum component|flagellar part|microtubule-based flagellum part					Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. Also note that cilia and eukaryotic flagella are deemed to be equivalent.	GO:0005929				True	GO:0044442		cellular_component											owl:Class	
GO:0005486	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0090198	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0017068	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1902715	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052518	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016766	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0005288	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0009776	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0046955	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0018986	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0010551	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0001037	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0042977	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0043789	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0005224	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0051530	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052090	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015241	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0042035	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0023015	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0048218	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0042154	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0002379	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0051810	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052376	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0030065	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0042687	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0000391	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0031178	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016293	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0042229	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0000929	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0030357	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1900040	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0102016	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0044424	biolink:NamedThing	obsolete intracellular part	OBSOLETE. Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.	tmpzr1t_l9r_go_relaxed.owl						Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.	GO:0005622				True			cellular_component											owl:Class	
GO:0018931	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0019195	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016452	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0044437	biolink:NamedThing	obsolete vacuolar part	OBSOLETE. Any constituent part of a vacuole, a closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material.	tmpzr1t_l9r_go_relaxed.owl	vacuole component					Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.	GO:0005773				True			cellular_component											owl:Class	
GO:0071436	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0044430	biolink:NamedThing	obsolete cytoskeletal part	OBSOLETE. Any constituent part of the cytoskeleton, a cellular scaffolding or skeleton that maintains cell shape, enables some cell motion (using structures such as flagella and cilia), and plays important roles in both intra-cellular transport (e.g. the movement of vesicles and organelles) and cellular division. Includes constituent parts of intermediate filaments, microfilaments, microtubules, and the microtrabecular lattice.	tmpzr1t_l9r_go_relaxed.owl	cytoskeleton component|cytoskeletal element				NIF_Subcellular:sao1635329413	Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.	GO:0005856				True			cellular_component											owl:Class	
GO:0004759	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0001148	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0008969	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0043340	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0032858	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052045	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0009391	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052283	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
NCBITaxon:451866	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl																										
GO:0008844	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045383	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0021733	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052549	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045790	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0008007	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0005974	biolink:NamedThing	obsolete fibrinogen gamma chain	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	fibrinogen gamma chain					This term was made obsolete because it represents a single gene product and not a complex.	GO:0005577				True	GO:0008007		cellular_component											owl:Class	
GO:0033035	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016315	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0035586	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0019642	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0046767	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0102008	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0150192	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0043187	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0051820	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0003927	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0048128	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0032319	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0001902	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016954	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0036327	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052501	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0008596	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0007456	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052441	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0010806	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0046801	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0001105	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0072623	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0030028	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0006916	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0004762	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0001043	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045080	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0004101	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0072510	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0048594	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0008799	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0008722	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015206	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0003749	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015065	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052290	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0004330	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0006871	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0004469	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0048590	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045525	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1904168	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0006347	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0042831	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0005089	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0001158	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016789	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0006263	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015320	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0048435	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0001226	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0070261	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0050753	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0048410	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0090662	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0042091	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0072630	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0010627	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1902765	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0006150	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0051207	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0004886	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0047210	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0002743	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0050722	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0008274	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052161	biolink:NamedThing	obsolete modulation by symbiont of defense-related host cell wall thickening	OBSOLETE. Any process in which an organism modulates the frequency, rate or extent of host processes resulting in the thickening of its cell walls, occurring as part of the defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	modulation by organism of host defensive cell wall thickening|modulation by organism of defense-related cell wall thickening in other organism involved in symbiotic interaction					This term was obsoleted because it is a host, not a symbiont process, but was formulated as a symbiont process.					True	GO:0052300		biological_process											owl:Class	
GO:2000072	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016478	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015268	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045416	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015656	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1990821	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0005970	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0033724	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0003894	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0006087	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0009816	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0019984	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0042002	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0050755	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1990939	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0044370	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0048637	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0072465	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0090645	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0014026	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0032521	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0000359	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045414	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1903263	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0090569	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0000057	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1904455	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0047752	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0031239	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0062178	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1990118	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0002073	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0000069	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052532	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GOP:chebi_ph7_3	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl						Rhea list of ChEBI terms representing the major species at pH 7.3.																			owl:AnnotationProperty	
GO:0046742	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0019012	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015281	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016928	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015033	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0033682	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052538	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0090002	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0000498	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0030347	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0000924	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0072615	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0090458	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0051242	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0001908	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0031792	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0008644	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0072654	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045532	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0000926	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045535	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0097349	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0008095	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045384	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0042224	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016097	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0061012	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0030605	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0046837	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0072613	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0009283	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016820	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0001749	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0009552	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045447	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0043341	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0000063	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0030608	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0044714	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0051825	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0075717	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0044234	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052306	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0044254	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0048122	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0046750	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0048155	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0005472	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045401	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0009775	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0048126	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0009241	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0048551	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016960	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015511	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0036231	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052030	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0005716	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0018843	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0090142	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0033955	biolink:NamedThing	obsolete mitochondrial DNA inheritance	OBSOLETE. The process in which copies of the mitochondrial genome are distributed into daughter mitochondria upon mitochondrial fission.	tmpzr1t_l9r_go_relaxed.owl	mitochondrial chromosome segregation|mitochondrial DNA segregation	https://github.com/geneontology/go-ontology/issues/18417				This term was obsoleted because it represented a phenotype.	GO:0000266|GO:0000002				True	GO:0090142		biological_process											owl:Class	
GO:0045388	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0004870	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0072425	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016745	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0033297	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0019167	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0019986	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0050576	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0032522	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0048059	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045374	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0042097	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1902067	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:2000666	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0007045	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0061166	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0043016	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052278	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1902187	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045394	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0023016	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015610	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0001136	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016033	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0001202	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0006442	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:2000664	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0072611	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0042143	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0043439	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0035549	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1900401	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0051505	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1905419	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0010175	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0000058	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0048862	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1990681	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0051910	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0004884	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045280	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015536	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0030928	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0048412	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052370	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045404	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0044699	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016017	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0003695	biolink:NamedThing	obsolete random coil DNA binding	OBSOLETE. Binding to DNA in a random coil configuration.	tmpzr1t_l9r_go_relaxed.owl	random coil binding	https://github.com/geneontology/go-ontology/issues/18879				This term was obsoleted because the definition was not clear enough as to what is directing specificity of the binding to the DNA.					True	GO:0016017		molecular_function											owl:Class	
GO:0102260	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0005904	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0048602	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0050880	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0031187	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0000042	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016535	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0050827	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0090005	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0051426	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0046699	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0090469	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1903275	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1903718	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0007067	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016450	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0051025	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0071143	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0043359	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0071884	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0033109	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0019754	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0060871	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015329	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0047076	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0061600	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0006872	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0009586	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016089	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1904469	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0001644	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0048271	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0044415	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0042375	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0051868	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:2000598	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0033725	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0009878	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0048414	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1904467	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045397	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015286	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0003760	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1902593	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0044455	biolink:NamedThing	obsolete mitochondrial membrane part	OBSOLETE. Any constituent part of a mitochondrial membrane, either of the lipid bilayers that surround the mitochondrion and form the mitochondrial envelope.	tmpzr1t_l9r_go_relaxed.owl						Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.	GO:0031966				True			cellular_component											owl:Class	
GO:0019967	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1990614	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0072601	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052537	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015290	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1990307	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0002166	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0006445	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015502	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0019041	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0035104	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0009405	biolink:NamedThing	obsolete pathogenesis	OBSOLETE. The set of specific processes that generate the ability of an organism to induce an abnormal, generally detrimental state in another organism.	tmpzr1t_l9r_go_relaxed.owl	virulence	https://github.com/geneontology/go-ontology/issues/11057				This term was obsoleted because it does not describe a single, normal biological process; rather it is the effect of an interaction between two organisms, under specific conditions.	GO:0044003|GO:0052031|GO:0052042				True			biological_process											owl:Class	
GO:0042109	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0005386	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1900173	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0003699	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0150124	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1902478	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0019965	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1901134	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0001035	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1901476	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1990945	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0048426	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1905659	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0075142	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0150150	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0103115	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045553	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0048428	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0044086	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0044259	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0001023	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0048591	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0008680	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0003907	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0004944	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0007104	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0048419	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0043205	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015852	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015181	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0042257	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0006342	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0001585	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0042225	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0008708	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0005226	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016424	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0007082	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0001126	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0070010	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0004899	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0000081	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0009434	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0002390	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0030454	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0051244	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0009281	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0034619	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0019581	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0018385	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0140564	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0006519	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0035547	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:2000507	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0044055	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045845	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0030571	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0089711	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0030468	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0050710	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0009598	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0018514	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0042227	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1901690	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0004003	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0001031	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0075501	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0008647	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0001144	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0005090	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045001	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052268	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0008629	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0033733	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0150149	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0046732	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1901603	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0099131	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0010552	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0032894	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0102315	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0046768	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0001032	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1902578	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0030333	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0008099	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0046751	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0042514	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0099097	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045082	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0051837	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1902023	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0070749	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0061505	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
NCBITaxon:3398	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl																										
GO:0007467	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015239	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0030607	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0001623	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0042521	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1990925	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0005341	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0097689	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0048096	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0002640	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0032844	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052405	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045362	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0019734	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0008400	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016228	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0000942	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0017073	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1902837	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0010699	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0050719	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0043437	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:2001180	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052250	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0060247	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045377	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0042553	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0044724	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0001203	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0072437	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0099603	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0042787	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015672	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0051828	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0034962	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1902377	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0044802	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0002374	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0019613	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0001220	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0048230	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0044797	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015809	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016924	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0019127	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0008338	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0035535	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0150194	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016976	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0006759	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0048004	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0072614	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045868	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0061164	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0072516	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0006443	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1902454	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0033170	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052251	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0003897	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0071841	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0060248	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0102078	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0019225	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0000318	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0008249	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0008072	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0030025	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0046971	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0001044	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052179	biolink:NamedThing	obsolete metabolism by symbiont of host cell wall pectin	OBSOLETE. The chemical reactions and pathways performed by an organism involving pectin in the cell wall of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	metabolism by organism of cell wall pectin in other organism involved in symbiotic interaction					This term was obsoleted because it represents a molecular function.					True	GO:0052413		biological_process											owl:Class	
GO:0019565	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0042681	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0042241	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015609	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0001679	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0009572	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052267	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0007459	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0075122	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0048409	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015618	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016777	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0098668	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0061494	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015463	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052087	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1905121	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1905658	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0098738	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0044376	biolink:NamedThing	obsolete RNA polymerase II complex import to nucleus	OBSOLETE. The directed movement of the DNA-directed RNA polymerase II core complex from the cytoplasm into the nucleus.	tmpzr1t_l9r_go_relaxed.owl	RNA polymerase II complex localisation to nucleus|RNA polymerase II complex import into nucleus|DNA-directed RNA polymerase II core complex localization to nucleus|DNA-directed RNA polymerase II core complex import into nucleus					The reason for obsoletion is that all proteins are imported into the nucleus via the same mechanism, so the import of individual proteins should be captured with extensions or by GO-CAM models.	GO:0006606	jl	2011-12-01T04:43:03Z		True	GO:0098738		biological_process											owl:Class	
GO:0005103	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0043349	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1990293	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0000046	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0150160	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0006375	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0048433	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052535	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016001	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0005913	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0009121	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0003737	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0035638	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015580	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0000986	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015585	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0042871	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0005331	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0042516	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0008916	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0042510	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0010534	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0032146	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045398	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0017152	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0030039	biolink:NamedThing	obsolete DNA unwinding factor	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	DNA unwinding factor			GO:0006268		This term was made obsolete because it does not represent a true molecular function.					True	GO:0017152		molecular_function											owl:Class	
GO:0038042	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045357	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1990766	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1902150	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0044464	biolink:NamedThing	obsolete cell part	OBSOLETE. Any constituent part of a cell, the basic structural and functional unit of all organisms.	tmpzr1t_l9r_go_relaxed.owl	cellular subcomponent|protoplast				NIF_Subcellular:sao628508602	Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.	CL:0000000				True			cellular_component											owl:Class	
GO:0052056	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052564	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0030024	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0006138	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015906	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0019193	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0075327	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015664	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0005285	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0097357	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0000283	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0048186	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0000509	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:2000021	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1990286	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052509	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052060	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1903756	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0001599	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1904208	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052281	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0102567	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0005961	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0000141	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0019721	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0043832	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0044021	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0070924	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1990598	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045731	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0046489	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0030615	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0000780	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0090004	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0071992	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0018841	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052632	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0017016	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0018691	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0061747	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052284	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0004012	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0072617	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0042434	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0043361	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0019735	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0006818	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0048606	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0102609	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0090544	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0018476	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0150169	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0022415	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0006348	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0072471	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0048751	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052071	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0001638	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0001633	biolink:NamedThing	obsolete secretin-like receptor activity	OBSOLETE. A G protein-coupled receptor that is structurally/functionally related to the secretin receptor.	tmpzr1t_l9r_go_relaxed.owl	secretin-like receptor activity|class B G-protein coupled receptor|class B G protein coupled receptor|class B GPCR|class B orphan receptor activity					This term was made obsolete because it represents a gene product and is named based on protein features.					True	GO:0001638		molecular_function											owl:Class	
GO:0045846	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0019190	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0035058	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0072433	biolink:NamedThing	obsolete detection of DNA damage stimulus involved in mitotic G2 DNA damage checkpoint	OBSOLETE. The series of events in which information about damage to DNA is received and converted into a molecular signal, contributing to a mitotic G2/M transition DNA damage checkpoint.	tmpzr1t_l9r_go_relaxed.owl	mitotic G2/M transition DNA damage checkpoint sensor mechanism|detection of DNA damage stimulus involved in G2/M transition DNA damage checkpoint|mitotic G2/M transition DNA damage checkpoint sensor process|detection of DNA damage stimulus involved in mitotic G2/M transition DNA damage checkpoint|sensing involved in G2/M transition DNA damage checkpoint|detection of DNA damage stimulus involved in G2 DNA damage checkpoint|G2/M transition DNA damage checkpoint sensor mechanism|sensing involved in mitotic G2/M transition DNA damage checkpoint	https://github.com/geneontology/go-ontology/issues/20976				This term was obsoleted because it corresponds to a molecular function.		mah	2010-12-08T04:43:14Z		True	GO:0072424		biological_process											owl:Class	
GO:0000168	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0048112	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0018842	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0008590	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0038052	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0008264	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0000043	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0000443	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016451	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0042032	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0042055	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052265	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0090197	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0103052	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0046747	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015510	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0008368	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0000130	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0030914	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0071845	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0005487	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0043222	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016294	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0009599	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0004008	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045079	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0075517	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0006381	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0042526	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0018224	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015384	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0044436	biolink:NamedThing	obsolete thylakoid part	OBSOLETE. Any constituent part of a thylakoid, a sac-like vesicle that bears the photosynthetic pigments in photosynthetic organisms.	tmpzr1t_l9r_go_relaxed.owl						Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.	GO:0009579				True			cellular_component											owl:Class	
GO:0019949	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0018348	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1990774	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0005855	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0004907	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016291	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0031195	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0044708	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015582	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0000068	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0047318	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0051183	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1903308	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0008857	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015508	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0072652	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0002217	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0001151	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0019913	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0072646	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0030260	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045369	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052082	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0000396	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052311	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052202	biolink:NamedThing	obsolete negative regulation by symbiont of defense-related host cell wall callose deposition	OBSOLETE. Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of the deposition of callose by the host in its cell walls, occurring as part of the defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	down regulation by symbiont of defense-related host cell wall callose deposition|down-regulation by symbiont of defense-related host cell wall callose deposition|negative regulation by organism of defense-related callose deposition in other organism involved in symbiotic interaction|negative regulation by organism of defense-related cell wall callose deposition in other organism involved in symbiotic interaction|downregulation by symbiont of defense-related host cell wall callose deposition|negative regulation by symbiont of defense-related host callose deposition|inhibition by symbiont of defense-related host cell wall callose deposition					This term was obsoleted because it is a host, not a symbiont process, but was formulated as a symbiont process.					True	GO:0052311|GO:0052087|GO:0052282		biological_process											owl:Class	
GO:0097404	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0043191	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045529	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0071148	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0000490	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045441	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0051535	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0003757	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0060554	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0072638	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0072406	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0032947	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0043147	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0048553	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0042115	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0008323	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0000317	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0017137	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0042146	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052533	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0038126	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0034960	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0099114	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0018318	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0008560	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0046796	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0000071	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045908	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015845	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0005661	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0003892	biolink:NamedThing	obsolete proliferating cell nuclear antigen	OBSOLETE. A nuclear protein that associates as a trimer and then interacts with delta DNA polymerase and epsilon DNA polymerase, acting as an auxiliary factor for DNA replication and DNA repair.	tmpzr1t_l9r_go_relaxed.owl	proliferating cell nuclear antigen|PCNA					This term was made obsolete because describing something as an 'antigen' means that an organism can produce antibodies to it, which says nothing about the gene product activity.					True	GO:0005661		molecular_function											owl:Class	
GO:0044711	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0038051	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0000816	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052443	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0072401	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0004684	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0006374	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0051805	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0042518	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:2000189	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0043787	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0006938	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0039676	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0042515	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052037	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:2000365	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0035734	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016489	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0009520	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052271	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0042534	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052264	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015758	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0035258	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0042828	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015785	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015584	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0043284	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0035056	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0008827	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0005232	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0043141	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0001030	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0075057	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:2001202	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0003768	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0003767	biolink:NamedThing	obsolete co-chaperone activity	OBSOLETE. Co-chaperones are proteins that bind to chaperones and this complex then folds misfolded proteins. Co-chaperones by themselves do not possess chaperone activity.	tmpzr1t_l9r_go_relaxed.owl	co-chaperone activity					This term was made obsolete because it represents a class of gene products rather than a molecular function.	GO:0051087|GO:0044183|GO:0006457				True	GO:0003769|GO:0003771|GO:0003768|GO:0003770		molecular_function											owl:Class	
GO:0031675	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015162	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0046769	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0006455	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0005959	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0005329	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0098701	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0007012	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0097521	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0001218	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016219	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0032856	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0006492	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0001187	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015579	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0018840	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0008221	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0018354	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0010000	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0004891	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0006822	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052529	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1903458	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0072428	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0019459	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0044004	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045371	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0034509	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0034100	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0022892	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016619	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0005699	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0090456	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0005312	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016908	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0061601	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052255	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0012504	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045393	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0042346	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0003705	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0006215	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0060246	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0072661	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0006485	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0048121	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0032862	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052309	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0001201	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0048117	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0002928	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0005671	biolink:NamedThing	obsolete Ada2/Gcn5/Ada3 transcription activator complex	OBSOLETE. A multiprotein complex that possesses histone acetyltransferase and is involved in regulation of transcription. Contains either GCN5 or PCAF in a mutually exclusive manner. The budding yeast complex includes Gcn5p, two proteins of the Ada family, and two TBP-associate proteins (TAFs); analogous complexes in other species have analogous compositions, and usually contain homologs of the yeast proteins. Both ATAC- or SAGA (see GO:0000124, SAGA complex) are involved in the acetylation of histone H3K9 and K14 residues.	tmpzr1t_l9r_go_relaxed.owl	ATAC complex	https://github.com/geneontology/go-ontology/issues/21335				This term was obsoleted because it was incorrectly annotated. Consider ADA complex ; GO:0140671 or ATAC complex; GO:0140672.	GO:0140672|GO:0140671				True	GO:0002928		cellular_component											owl:Class	
GO:0035055	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0019925	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0072569	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0000173	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0050717	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1902149	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0061495	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0042477	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0018709	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0102005	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0043193	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0008862	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0000129	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0032850	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0044367	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052248	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0000982	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0019014	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1901689	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0043091	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0031189	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052347	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
NCBITaxon:33083	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl																										
GO:0071790	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0044263	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0055133	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0003740	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045365	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0032312	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1900920	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0044452	biolink:NamedThing	obsolete nucleolar part	OBSOLETE. Any constituent part of a nucleolus, a small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis.	tmpzr1t_l9r_go_relaxed.owl	nucleolus component					Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.	GO:0005730				True			cellular_component											owl:Class	
GO:0048231	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0035786	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0006331	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0006330	biolink:NamedThing	obsolete single-stranded DNA binding	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	single-stranded DNA binding			GO:0003697		This term was made obsolete because it represents a molecular function and not a biological process.					True	GO:0006332|GO:0006331		biological_process											owl:Class	
GO:0061745	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0008958	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0017019	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015456	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0005370	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0030102	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0004472	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0004010	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0035086	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1902968	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0034226	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0098546	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0044445	biolink:NamedThing	obsolete cytosolic part	OBSOLETE. Any constituent part of cytosol, that part of the cytoplasm that does not contain membranous or particulate subcellular components.	tmpzr1t_l9r_go_relaxed.owl	cytosol component					Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.	GO:0005829				True			cellular_component											owl:Class	
GO:0050713	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0009596	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0072511	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0005333	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0006966	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0007452	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1900174	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0048434	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1905963	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015999	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0043764	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0102023	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015646	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1990288	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0001008	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016253	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0075518	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015684	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052101	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016224	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0046613	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0090623	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0019753	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0048552	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0005772	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0051808	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1901473	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0051526	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015326	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0071862	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0070882	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045359	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0017100	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1901138	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015688	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0006861	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0102568	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0042041	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045425	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0005843	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0039515	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0008433	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0032852	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0032022	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0043775	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052077	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0034961	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0075143	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0075141	biolink:NamedThing	obsolete symbiont tolerance to host environment	OBSOLETE. Any process that contributes to the maintenance of a physiologic state in which the symbiont immune system does not react destructively against the components of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	maintenance of symbiont tolerance to host oxygen tension environment|maintenance of symbiont tolerance to host redox environment|maintenance of symbiont tolerance to host iron concentration|maintenance of symbiont tolerance to host pH environment|maintenance of symbiont tolerance to host environment|maintenance of symbiont tolerance to host osmotic environment	https://github.com/geneontology/go-ontology/issues/19099|https://github.com/geneontology/go-ontology/issues/18827				This term was obsoleted because it is redundant with other terms.	GO:0052200				True	GO:0075238|GO:0075143|GO:0075146|GO:0075144|GO:0075142		biological_process											owl:Class	
GO:0098602	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0039601	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0051869	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1902316	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0031454	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0018806	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0006321	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0050663	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0004302	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0007324	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0009796	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015404	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0035427	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0035083	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0098741	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045361	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052428	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052663	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0044756	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0072643	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052380	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0072416	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016927	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0001209	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0005320	biolink:NamedThing	obsolete apolipoprotein	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	apolipoprotein					This term was made obsolete because it does not represent a molecular function.	GO:0005319				True	GO:0015907		molecular_function											owl:Class	
GO:0016959	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0018088	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0006870	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0005040	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0007410	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0061167	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1990336	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0030452	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0034500	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0043345	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045034	biolink:NamedThing	obsolete neuroblast division	OBSOLETE. The asymmetrical division of a neuroblast, the neural precursor in the central nervous system, giving rise to another neuroblast and a ganglion mother cell.	tmpzr1t_l9r_go_relaxed.owl	neuroblast division (sensu Nematoda and Protostomia)|neuroblast cell division|neuroblast division (sensu Vertebrata)|neuroblast division					This term was made obsolete because the definition was incorrect. Not all neuroblasts divide asymmetrically. Neuroblasts give rise to neurons after division.					True	GO:0043345|GO:0043346		biological_process											owl:Class	
GO:0006093	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0103024	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1903874	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1903758	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052280	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0140554	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0008639	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0150120	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0008557	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0036459	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0044006	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016069	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0043690	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0043926	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0044054	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0071822	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0042295	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0017127	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0032439	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0048049	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0042036	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016563	biolink:NamedThing	obsolete transcription activator activity	OBSOLETE. Any transcription regulator activity required for initiation or upregulation of transcription.	tmpzr1t_l9r_go_relaxed.owl	transcription activating factor|transcription activator activity|transcriptional activator activity			GO:0001228		This term was obsoleted because it is essentially identical to a Process term (specifically the Biological Process term which has been selected as a term to consider for reannotation), i.e. it is defined only in terms of the process it acts in and it does NOT convey any information about the molecular nature of the function or whether the function is based on binding DNA, on interacting with other proteins, or some other mechanism. To transfer all annotations without review, the BP term indicated is considered to be equivalent and thus the only appropriate destination for all annotations. To reannotate to a MF term, you will probably need to revisit the original literature or other primary data because this "MF" term was not defined in terms of mechanism of action and there are multiple possibilities in the revised MF structure. In reannotation, please also consider descendent terms of the suggested MF terms as a more specific term may be more appropriate than the MF terms indicated. Please be aware that you may wish to request a new term if the mechanism of action of this gene product is not yet represented or if you are annotating for an RNAP different than one for which there is a specific suggested term. Also note that if there is no information about how the gene product acts, it may be appropriate to annotate to the root term for molecular_function.					True	GO:0003710		molecular_function											owl:Class	
GO:0048175	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0001622	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016792	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1902293	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0001106	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0030069	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0031988	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0000004	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016177	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0003889	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0042513	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0046744	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0031206	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0048287	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0042411	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0003946	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015639	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052930	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015893	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0034621	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045288	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0010579	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0017066	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:2000483	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0030898	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015077	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:2000823	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0003126	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0043285	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016534	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0022833	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1903262	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015202	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016244	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0150122	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0005676	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0018409	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0009795	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0001133	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052152	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0035537	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0008632	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0009287	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015409	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016537	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0007103	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0043106	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1990282	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0042830	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0003763	biolink:NamedThing	obsolete chaperonin ATPase activity	OBSOLETE. Catalysis of the reaction: ATP + H2O = ADP + phosphate. The hydrolysis of ATP involved in maintaining an unfolded polypeptide structure before folding or to entry into mitochondria and chloroplasts.	tmpzr1t_l9r_go_relaxed.owl	chaperonin|chaperonin ATPase activity			GO:0016887		This term was made obsolete because it represents a class of gene products, and its definition incorporates process information.	GO:0006457				True	GO:0003766|GO:0003764|GO:0003765		molecular_function											owl:Class	
GO:0042782	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0044371	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0043142	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0008731	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0004182	biolink:NamedThing	obsolete carboxypeptidase A activity	OBSOLETE. Catalysis of the reaction: peptidyl-L-amino acid + H2O = peptide + L-amino acid. Little or no action with -Asp, -Glu, -Arg, -Lys or -Pro.	tmpzr1t_l9r_go_relaxed.owl	pancreatic carboxypeptidase A|tissue carboxypeptidase A|carboxypeptidase A activity|carboxypolypeptidase activity			GO:0004181		This term was made obsolete because it represents a gene product.					True	GO:0008731		molecular_function											owl:Class	
GO:0045366	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0019006	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0019425	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0007609	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0009591	biolink:NamedThing	obsolete perception of mechanical stimulus	OBSOLETE. The series of events by which a mechanical stimulus is received by a cell and converted into a molecular signal.	tmpzr1t_l9r_go_relaxed.owl	perception of mechanical stimulus					This term was made obsolete because it was not clear whether the term applied to the whole process of taste perception or just the sensory transduction stage.	GO:0050954				True	GO:0007609		biological_process											owl:Class	
GO:0072459	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0048253	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0003123	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0044213	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045395	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0006752	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016470	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0006472	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0031200	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
NCBITaxon:131567	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl																										
GO:0004840	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0071997	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0044413	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0034712	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0070615	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052065	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1902452	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0098611	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0042536	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0007151	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0022820	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1903834	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052258	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0033753	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016568	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0044266	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0019009	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0002137	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0097286	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1904805	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0000944	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0006980	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0046731	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0043080	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015455	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0008620	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0023046	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0033710	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0150125	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045877	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0098589	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1905361	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0005485	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0001122	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015249	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0034449	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0048405	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0097024	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0072605	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0042523	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0001041	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0006453	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0006773	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0008102	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0036263	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0103095	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0009364	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0051689	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0005909	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015623	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045538	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0001077	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0046515	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0005062	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0018382	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0007037	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0003765	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0006594	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0000385	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0090195	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0003738	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052345	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0044119	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0075146	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0051076	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0050724	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0042674	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0033318	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0030664	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0008468	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045255	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0048130	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0006395	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045154	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0043432	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0061165	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0007022	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0072640	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0019963	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0031198	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0072450	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0032321	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0044447	biolink:NamedThing	obsolete axoneme part	OBSOLETE. Any constituent part of an axoneme, the bundle of microtubules and associated proteins that forms the core of cilia (also called flagella) in eukaryotic cells and is responsible for their movements.	tmpzr1t_l9r_go_relaxed.owl	axonemal part					Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. Also note that cilia and eukaryotic flagella are deemed to be equivalent.	GO:0005930				True			cellular_component											owl:Class	
GO:0048272	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015246	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0072440	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016449	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:2001041	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0061994	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0004279	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0006764	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0000505	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0007372	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0072443	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0097461	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0048422	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0004700	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015402	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0072641	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045392	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0000125	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0007255	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0000984	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0003728	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0018375	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0150113	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0042087	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0055128	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0001613	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0017173	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0035085	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045402	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0008279	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045207	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045206	biolink:NamedThing	obsolete MAPK phosphatase transporter activity	OBSOLETE. Enables the directed movement of MAPK phosphatase into, out of or within a cell, or between cells.	tmpzr1t_l9r_go_relaxed.owl	MKP shuttle|MAPK phosphatase transporter activity|leptomycin B-sensitive MAPK phosphatase transporter activity|leptomycin B-sensitive MKP shuttle					This term was made obsolete because we do not know what it was intended to represent when it was created.					True	GO:0045207		molecular_function											owl:Class	
GO:0015388	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0150133	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1902398	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0051024	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016523	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0006765	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0032315	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0009484	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0009482	biolink:NamedThing	obsolete ba3-type cytochrome c oxidase	OBSOLETE. Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: 4 ferrocytochrome c + O2 = 4 ferricytochrome c + 2 H2O.	tmpzr1t_l9r_go_relaxed.owl	ba3-type cytochrome c oxidase			GO:0004129		This term was made obsolete because it describes a class of gene products rather than a molecular function.					True	GO:0009484		molecular_function											owl:Class	
GO:0048432	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0019275	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0000420	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0017160	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0090568	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1902828	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0043352	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0106311	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052276	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0006010	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0007327	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0003895	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0005306	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0004188	biolink:NamedThing	obsolete serine-type Pro-X carboxypeptidase activity	OBSOLETE. Catalysis of the cleavage of a Pro-Xaa bond by a serine-type peptidase mechanism to release a C-terminal amino acid.	tmpzr1t_l9r_go_relaxed.owl	lysosomal Pro-X carboxypeptidase activity|lysosomal Pro-Xaa carboxypeptidase activity|proline-specific carboxypeptidase P|proline carboxypeptidase activity|serine-type Pro-X carboxypeptidase activity|peptidylprolylamino acid carboxypeptidase activity|PCP|lysosomal carboxypeptidase C activity|angiotensinase C activity|prolyl carboxypeptidase activity|aminoacylproline carboxypeptidase activity			GO:0004185		This term was made obsolete because it represents a gene product.					True	GO:0008323		molecular_function											owl:Class	
GO:0052510	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0050715	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0001185	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0005032	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0004718	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0061021	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0019691	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0042505	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0034623	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0033649	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0042253	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016440	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0042963	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0000789	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0044426	biolink:NamedThing	obsolete cell wall part	OBSOLETE. Any constituent part of the cell wall, the rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal, and most prokaryotic cells, maintaining their shape and protecting them from osmotic lysis.	tmpzr1t_l9r_go_relaxed.owl						Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.	GO:0005618				True			cellular_component											owl:Class	
GO:0003124	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0044710	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0043356	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0000778	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0000066	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0006993	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016142	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0006763	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0000999	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1903414	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0018239	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0042535	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0042508	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0002380	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015563	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0042484	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0004405	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015122	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0006243	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1990141	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0010107	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0009797	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0000119	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0005718	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0005972	biolink:NamedThing	obsolete fibrinogen alpha chain	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	fibrinogen alpha chain					This term was made obsolete because it represents a single gene product and not a complex.	GO:0005577				True	GO:0008005		cellular_component											owl:Class	
GO:0050874	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:2000484	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0019282	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1903990	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0031662	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
NCBITaxon:7742	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl																										
GO:0010388	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0009369	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0004871	biolink:NamedThing	obsolete signal transducer activity	OBSOLETE. Conveys a signal across a cell to trigger a change in cell function or state. A signal is a physical entity or change in state that is used to transfer information in order to trigger a response.	tmpzr1t_l9r_go_relaxed.owl	quorum sensing signal generator activity|quorum sensing response regulator activity|hematopoietin/interferon-class (D200-domain) cytokine receptor signal transducer activity	https://github.com/geneontology/go-ontology/issues/14232				This term was obsoleted because it was not clearly defined and is not a useful grouping term.					True	GO:0009369|GO:0005062|GO:0009370		molecular_function											owl:Class	
GO:0072445	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0031743	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0010173	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0031513	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0043119	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0019007	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0018440	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1990296	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0005720	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1900476	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1904497	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0044712	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016003	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015058	biolink:NamedThing	obsolete epidermal growth factor-like module containing hormone receptor activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	EGF-like module containing hormone receptor activity|epidermal growth factor-like module containing hormone receptor activity|Egr1 hormone receptor					This term was made obsolete because it represents a gene product, was not defined, and is named based on protein features.					True	GO:0016523		molecular_function											owl:Class	
GO:0052295	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0000158	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0005478	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0071779	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0090608	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0072628	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0008640	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0050721	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0008600	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0043343	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0043109	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015784	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0000728	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0072561	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1903956	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0000945	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0090484	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1900172	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0000975	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0070011	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0030375	biolink:NamedThing	obsolete thyroid hormone receptor coactivator activity	OBSOLETE. The function of a transcription cofactor that activates transcription in conjunction with a thyroid hormone-dependent nuclear receptor from a RNA polymerase II promoter; does not bind DNA itself.	tmpzr1t_l9r_go_relaxed.owl	thyroid hormone receptor co-activator activity|thyroid hormone receptor activator activity					This term was obsoleted because it represented a gene product.					True	GO:0010861		molecular_function											owl:Class	
GO:0000507	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0001160	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016931	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0010237	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0002506	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0048421	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015557	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0019737	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0050876	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0044723	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
NCBITaxon:27896	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl																										
GO:1903989	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015873	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0051852	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0061488	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045909	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0000106	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0044798	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0070838	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0030231	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1902411	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016542	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0046652	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016967	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0030503	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015321	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0032845	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0019053	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0019582	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0018869	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0019850	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0072636	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0017031	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016181	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0007333	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0008243	biolink:NamedThing	obsolete plasminogen activator activity	OBSOLETE. Catalysis of the specific cleavage of an Arg-Val bond in plasminogen to form plasmin.	tmpzr1t_l9r_go_relaxed.owl	urinary esterase A|t-plasminogen activator activity|abbokinase activity|tissue-type plasminogen activator activity|u-PA|tissue plasminogen activator activity|tPA activity|plasminogen activator activity|two-chain urokinase-type plasminogen activator|cellular plasminogen activator activity|plasminogen activator, tissue-type|t-PA|urinary plasminogen activator activity|uPA|u-plasminogen activator activity|double-chain urokinase-type plasminogen activator|urokinase activity|urokinase plasminogen activator|urokinase-type plasminogen activator			GO:0004252		This term was made obsolete because it represents a gene product.					True	GO:0004297|GO:0004296		molecular_function											owl:Class	
GO:0042520	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1903820	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0004943	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0031744	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0070604	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0009105	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0017140	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0042312	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0048404	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0090196	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0035257	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0043566	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0050723	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0007325	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0017049	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0006411	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0044279	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0000382	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0032512	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0007331	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1902585	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0000925	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0019077	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1904169	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0048595	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0017144	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015380	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0001670	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0008128	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0031636	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0090477	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0000157	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045440	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0070389	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0055099	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0050707	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0005162	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0004682	biolink:NamedThing	obsolete protein kinase CK2 activity	OBSOLETE. Catalysis of the reaction: casein + ATP = phosphocasein + ADP.	tmpzr1t_l9r_go_relaxed.owl	casein kinase II, catalytic activity|protein kinase CK2, intrinsic catalyst activity|protein kinase CK2 activity|casein kinase II activity			GO:0004674		This term was made obsolete because it represents a gene product.					True	GO:0008604		molecular_function											owl:Class	
GO:1902420	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1905965	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0032864	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0001034	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0004889	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0019088	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0007582	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0051832	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0043071	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0018373	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0002535	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015564	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0008749	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052490	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0031182	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052853	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0070627	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0048120	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1990369	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1903813	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0008367	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0051635	biolink:NamedThing	obsolete bacterial cell surface binding	OBSOLETE. Binding to a component on the surface of a bacterial cell.	tmpzr1t_l9r_go_relaxed.owl	bacterial binding|bacterial cell surface binding|binding to bacterium|bacterium cell surface binding|bacterium binding					This term was made obsolete because it is ambiguous and causing confusion, and is an unnecessary grouping term.	GO:0003823|GO:0042742|GO:0005102				True	GO:0008367		molecular_function											owl:Class	
GO:0035117	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016950	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1990415	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0008032	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0006350	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0042239	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045811	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0072462	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1990087	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0035534	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0003981	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015512	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0035587	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0061717	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0005403	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0010535	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0030542	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0072693	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0048415	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0008105	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052561	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0043809	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0150135	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1903410	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0055031	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045077	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:2001052	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0048124	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
OBO:go.owl	biolink:NamedThing	Gene Ontology	The Gene Ontology (GO) provides a framework and set of concepts for describing the functions of gene products from all organisms.	tmpzr1t_l9r_go_relaxed.owl										gene_ontology			1.2					http://creativecommons.org/licenses/by/4.0/							owl:Ontology	2021-11-16
OBO:go/releases/2021-11-16/go.owl	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl																										
GO:0015659	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0042591	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0018092	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045788	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0000799	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0001104	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045554	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0022891	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0071158	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0033669	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0017115	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052059	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0036328	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0050756	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0150112	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0072626	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0003898	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0001943	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0019951	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0032318	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1902453	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0072632	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0048554	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045215	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1903802	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0019063	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045573	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0005653	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0042604	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0008461	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045674	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0080174	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0010532	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0001194	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0048274	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0090479	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0042094	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0032054	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1902467	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015027	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0051531	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0000983	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045789	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0071842	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0038050	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0005857	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015831	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0043344	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0004036	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0070683	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0044763	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0001521	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0060626	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0032854	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045355	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0019739	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0030361	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1990975	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0018223	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052282	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0035548	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0004976	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045817	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0072018	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0044707	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0001013	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015028	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0043192	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0072418	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0072397	biolink:NamedThing	obsolete detection of stimulus involved in cytokinesis checkpoint	OBSOLETE. The series of events in which information about the formation and integrity of cytokinetic structures, such as the contractile ring, is received and converted into a molecular signal, contributing to a cytokinesis checkpoint.	tmpzr1t_l9r_go_relaxed.owl	cytokinesis checkpoint sensor mechanism|cytokinesis checkpoint sensor process|septin checkpoint sensor mechanism|sensing involved in cytokinesis checkpoint|septin checkpoint sensor process|detection of stimulus involved in septin checkpoint|sensing involved in septin checkpoint	https://github.com/geneontology/go-ontology/issues/20976				This term was obsoleted because it corresponds to a molecular function.		mah	2010-12-08T03:18:11Z		True	GO:0072418		biological_process											owl:Class	
GO:0044448	biolink:NamedThing	obsolete cell cortex part	OBSOLETE. Any constituent part of the cell cortex, the region of a cell that lies just beneath the plasma membrane and often, but not always, contains a network of actin filaments and associated proteins.	tmpzr1t_l9r_go_relaxed.owl						Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.	GO:0005938				True			cellular_component											owl:Class	
GO:0005453	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0005932	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0017034	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0007152	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0017033	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0009387	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0050791	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016685	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052277	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0044153	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0097459	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0150161	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045528	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0051471	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0010531	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0051375	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0008182	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016288	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0048141	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0031196	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052378	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0008183	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0034261	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1900921	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0010386	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0070750	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052289	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0031190	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0042266	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0032855	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0044252	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0009021	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0061748	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1905657	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052291	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0000985	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0018087	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016953	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016096	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1990152	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0043347	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0075056	biolink:NamedThing	obsolete negative regulation of penetration peg formation	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of symbiont penetration peg formation for entry into host. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of symbiont penetration peg formation for entry into host|negative regulation of symbiont penetration peg initiation	https://github.com/geneontology/go-ontology/issues/18779				This term was obsoleted because there is no evidence that this process exists.					True	GO:0075060		biological_process											owl:Class	
GO:0007233	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0070363	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0072083	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0008178	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0046674	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052293	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0035546	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0032066	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0044244	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052852	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0023014	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0001903	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0006902	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0051527	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0090302	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0009774	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015637	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0001589	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0032518	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016238	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0072625	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1990345	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015674	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0008339	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0008223	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0001205	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1900041	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016958	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0072472	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0044704	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0030179	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0061637	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0043706	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0004647	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0030524	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0009613	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045391	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0000441	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0031618	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:2000695	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0001123	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0001693	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0102353	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052329	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0043234	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:2000662	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0042678	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0004959	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0044356	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1903887	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015082	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015338	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0006365	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0043342	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0008665	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0075128	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052551	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0036232	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1903273	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0140160	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0042230	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0033057	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0017036	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0007373	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0002744	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0072634	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0030482	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0002386	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0001012	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0044700	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016736	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015683	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0042145	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0071991	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0042347	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0043239	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015197	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0030434	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0008602	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0046770	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0006947	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0051824	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0048111	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0003125	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0048605	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0072431	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1903835	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1903130	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0006961	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0019291	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0051297	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:2000482	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0007001	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0000351	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0072600	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0043762	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0005099	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0031238	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0043283	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0007461	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0018692	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0005033	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0050430	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0090041	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0000787	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045407	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0030113	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0048604	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0048115	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0043074	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045403	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0044421	biolink:NamedThing	obsolete extracellular region part	OBSOLETE. Any constituent part of the extracellular region, the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers constituent parts of the host cell environment outside an intracellular parasite.	tmpzr1t_l9r_go_relaxed.owl	extracellular structure				NIF_Subcellular:sao9117790637	Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.	GO:0005576				True			cellular_component											owl:Class	
GO:0015559	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1905122	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052931	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0044745	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
NCBITaxon:3378	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl																										
GO:0042345	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0043088	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0075121	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1904167	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0008026	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0001103	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0050443	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0009618	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0008372	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0070015	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0030966	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0090098	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0072691	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0051774	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0010953	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0018225	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0033317	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0098783	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0050381	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0004480	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0043742	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0021734	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052400	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0046734	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016400	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0048064	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052073	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1903991	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0150188	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0072394	biolink:NamedThing	obsolete detection of stimulus involved in cell cycle checkpoint	OBSOLETE. The series of events in which information about a biological process or quality is received and converted into a molecular signal, contributing to a cell cycle checkpoint.	tmpzr1t_l9r_go_relaxed.owl	G1/S transition checkpoint sensor process|G1/S transition checkpoint sensor mechanism|sensing involved in cell cycle checkpoint|G2/M transition checkpoint sensor process|detection of stimulus involved in G2/M transition checkpoint|sensing involved in G2/M transition checkpoint|cell cycle checkpoint sensor mechanism|detection of stimulus involved in G1/S transition checkpoint|sensing involved in G1/S transition checkpoint|cell cycle checkpoint sensor process|G2/M transition checkpoint sensor mechanism	https://github.com/geneontology/go-ontology/issues/20976				This term was obsoleted because it corresponds to a molecular function.		mah	2010-12-08T02:55:56Z		True	GO:0072403|GO:0072406		biological_process											owl:Class	
GO:0044285	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0051406	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052310	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052189	biolink:NamedThing	obsolete modulation by symbiont of defense-related host cell wall callose deposition	OBSOLETE. Any process in which an organism modulates the frequency, rate or extent of the deposition of callose by the host in its cell walls, occurring as part of the defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	modulation by organism of defense-related cell wall callose deposition in other organism involved in symbiotic interaction|modulation by organism of defense-related callose deposition of other organism involved in symbiotic interaction|modulation by symbiont of defense-related host callose deposition					This term was obsoleted because it is a host, not a symbiont process, but was formulated as a symbiont process.					True	GO:0052310|GO:0052285|GO:0052090		biological_process											owl:Class	
GO:0045675	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0035428	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015353	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052449	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1990541	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0071937	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0019699	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015892	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0072453	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0009565	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0009844	biolink:NamedThing	obsolete germination	OBSOLETE. The physiological and developmental changes by a seed, spore, pollen grain (microspore), or zygote that occur after release from dormancy, and encompassing events prior to and including the first visible indications of growth.	tmpzr1t_l9r_go_relaxed.owl	germination					This term was made obsolete because it is a grouping term without biological significance.					True	GO:0009565		biological_process											owl:Class	
GO:0035466	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0018804	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0055084	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016047	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052252	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0070752	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045546	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0031576	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0001150	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0051834	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0090157	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016249	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0007126	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0007322	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015570	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0090040	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0004524	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0075061	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1900922	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0042677	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0006770	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0031572	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0004429	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0048267	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015590	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0072407	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0019173	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0019818	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0036233	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0005088	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0019641	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0004297	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0044444	biolink:NamedThing	obsolete cytoplasmic part	OBSOLETE. Any constituent part of the cytoplasm, all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.	tmpzr1t_l9r_go_relaxed.owl	cytoplasm component					Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.	GO:0005737				True			cellular_component											owl:Class	
GO:0000074	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0000927	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1903310	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045256	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0030013	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0042222	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0000218	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0005830	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0008642	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0061022	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0001214	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
NCBITaxon:40674	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl																										
GO:0043037	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:2000665	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052186	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1902431	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0048044	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045044	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016220	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015632	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0030525	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1904804	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0006724	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0010553	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0051812	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0010805	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0090607	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1902304	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016800	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0005218	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0044440	biolink:NamedThing	obsolete endosomal part	OBSOLETE. Any constituent part of an endosome, a membrane-bounded organelle to which materials ingested by endocytosis are delivered.	tmpzr1t_l9r_go_relaxed.owl	endosome component|endosomal subcomponent				NIF_Subcellular:sao1683772610	Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.	GO:0005768				True			cellular_component											owl:Class	
GO:0035411	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0017167	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0050489	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015084	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0017138	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0044274	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0140045	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0019924	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0001225	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0030387	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016968	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045449	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0036281	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0039681	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0035389	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0061460	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0034984	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:2000663	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0044531	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0043925	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
NCBITaxon:147537	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl																										
GO:0008040	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1990284	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0044212	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052389	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0005067	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0003076	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045387	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0005378	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0047523	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0046650	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0004872	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0006318	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1903822	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052256	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0030045	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0030483	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0010204	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0019906	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015589	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0022838	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0072026	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0042833	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0044276	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0000029	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0008505	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0017191	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0043868	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0018552	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0150114	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052288	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0071850	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0051579	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0001718	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1900755	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0001005	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0006652	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0051768	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1990123	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0005051	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0051288	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0048221	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0008497	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1904190	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0000797	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0005719	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0006960	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1903809	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0001141	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0007046	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052262	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0043017	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0030384	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045084	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0030646	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0019494	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0075516	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052254	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045791	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016876	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0008059	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016660	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0043348	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0035856	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0001199	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0006160	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0047767	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0031374	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0001189	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0140362	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0043790	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0050706	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045235	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0018714	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0017123	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0035390	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0003753	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0003708	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0042298	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0005842	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0072413	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0061491	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1901237	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0034049	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1990746	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0070526	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052166	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0003769	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0006946	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015163	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0035326	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0004763	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0004710	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0042061	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0008321	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0009284	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0034048	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0030146	biolink:NamedThing	obsolete diuresis	OBSOLETE. The process of renal water excretion.	tmpzr1t_l9r_go_relaxed.owl	renal water excretion|positive regulation of renal water excretion|diuresis				Wikipedia:Diuresis	This term was made obsolete because its definition was inaccurate.	GO:0035810				True	GO:0003076		biological_process											owl:Class	
GO:0032895	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052269	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0001078	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0035926	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0046748	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0072474	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0075052	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0004426	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0048233	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0071150	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0004393	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0007153	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0072486	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052935	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0020012	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016666	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1990240	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0030967	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052299	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0019943	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0019945	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0075326	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0048181	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052854	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0044425	biolink:NamedThing	obsolete membrane part	OBSOLETE. Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.	tmpzr1t_l9r_go_relaxed.owl						Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.	GO:0016020				True			cellular_component											owl:Class	
GO:0044670	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0042261	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015725	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015460	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0042319	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0030462	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0019868	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0044690	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016448	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0000777	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015088	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015696	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0002214	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016196	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0030872	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0006461	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0044235	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0050702	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0102437	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0047477	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1903411	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1990301	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1902477	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0006992	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1904265	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1903129	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0001590	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0010580	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015405	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0006322	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0005023	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0009681	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0044451	biolink:NamedThing	obsolete nucleoplasm part	OBSOLETE. Any constituent part of the nucleoplasm, that part of the nuclear content other than the chromosomes or the nucleolus.	tmpzr1t_l9r_go_relaxed.owl						Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.	GO:0005654				True			cellular_component											owl:Class	
GO:0044123	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0007457	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0001211	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0001047	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1902361	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0001600	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0030044	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015586	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0046420	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0034273	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0008601	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0001213	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0030477	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1904696	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0001085	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0055032	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0042236	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0005382	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0075238	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0034566	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0002742	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016809	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0075710	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0019259	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0019110	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0048607	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0032004	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015236	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0034629	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0018728	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0023034	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0044411	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045422	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016947	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0030610	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0150148	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0000169	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0030481	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0044005	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0050875	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045354	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0035412	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045011	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015392	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0004696	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052558	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1902400	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0031193	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052527	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0031202	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0008952	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0018371	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016940	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0032859	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0019723	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0007243	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0075144	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015523	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:2000364	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1904621	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0048068	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0090468	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0090039	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0009370	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0021857	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0003982	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0031081	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0061019	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0001045	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0044433	biolink:NamedThing	obsolete cytoplasmic vesicle part	OBSOLETE. Any constituent part of cytoplasmic vesicle, a vesicle formed of membrane or protein, found in the cytoplasm of a cell.	tmpzr1t_l9r_go_relaxed.owl						Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.	GO:0031410				True			cellular_component											owl:Class	
GO:0008416	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0030873	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0000369	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0044400	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015619	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045423	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045072	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0042449	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0043346	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0032155	biolink:NamedThing	obsolete cell division site part	OBSOLETE. Any constituent part of the cell division plane, the eventual plane of cell division in a dividing cell.	tmpzr1t_l9r_go_relaxed.owl	cell division plane part					Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.	GO:0032153				True			cellular_component											owl:Class	
GO:0009592	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0032851	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0050222	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0044462	biolink:NamedThing	obsolete external encapsulating structure part	OBSOLETE. Any constituent part of an external encapsulating structure, a structure that lies outside the plasma membrane and surrounds the entire cell. This does not include the periplasmic space but does include the outer membrane (of gram negative bacteria) or cell wall (of yeast or Gram positive bacteria).	tmpzr1t_l9r_go_relaxed.owl						Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.	GO:0030312				True			cellular_component											owl:Class	
GO:0004434	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0100022	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0100021	biolink:NamedThing	obsolete regulation of iron ion transport by transcription from RNA polymerase II promoter	OBSOLETE. Any transcription from RNA polymerase II promoter process that regulates iron ion transport.	tmpzr1t_l9r_go_relaxed.owl	regulation of iron ion import by transcription from RNA polymerase II promoter					This term was obsoleted because it represents a GO-CAM model.		cjm	2015-04-02T04:13:19Z		True	GO:0100022		biological_process											owl:Class	
NCBITaxon:33682	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl																										
GO:0006319	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1904468	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052305	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0003679	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0007242	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0003739	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0070283	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0009122	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0019663	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0048042	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0042260	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0017097	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0061467	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0099516	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045360	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0019189	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016698	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0030499	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015118	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0051577	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052285	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1902419	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0001137	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0043018	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0102101	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052330	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0044420	biolink:NamedThing	obsolete extracellular matrix component	OBSOLETE. Any constituent part of the extracellular matrix, the structure lying external to one or more cells, which provides structural support for cells or tissues; may be completely external to the cell (as in animals) or be part of the cell (as often seen in plants).	tmpzr1t_l9r_go_relaxed.owl	extracellular matrix part					Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.	GO:0031012				True			cellular_component											owl:Class	
GO:0004011	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0004004	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0075145	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:2000824	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0008699	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0030230	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0046728	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045533	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0047226	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0001643	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0008067	biolink:NamedThing	obsolete metabotropic glutamate, GABA-B-like receptor activity	OBSOLETE. A G protein-coupled receptor that is structurally/functionally related to the metabotropic glutamate receptor.	tmpzr1t_l9r_go_relaxed.owl	class C GPCR|class C G-protein coupled receptor|class C G protein coupled receptor|metabotropic glutamate, GABA-B-like receptor activity|class C orphan receptor activity					This term was made obsolete because it represents a gene product and is named based on protein features.					True	GO:0001643|GO:0001645		molecular_function											owl:Class	
GO:0097460	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016245	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045286	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0019274	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052270	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0017079	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045867	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045420	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0150156	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0002422	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0051578	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0090478	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0035467	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0044702	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0000788	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045381	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0103019	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0048123	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052385	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0033681	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016030	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0042108	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045043	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0036347	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052153	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0007222	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0051374	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0046614	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1905964	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0008485	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0010003	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0008393	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0004688	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0072422	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0072618	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0050701	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0002163	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052824	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0038049	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0006345	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0008501	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0018540	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1904209	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015678	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045417	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0046746	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0017104	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045386	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0042228	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0031180	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0048127	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1900390	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045421	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0051528	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0044369	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016349	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0051811	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0071780	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0046756	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1900393	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0044110	biolink:NamedThing	obsolete growth involved in symbiotic interaction	OBSOLETE. The increase in size or mass of an organism occurring when the organism is in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	growth on or near surface of other organism involved in symbiotic interaction|growth on or near surface of other organism during symbiotic interaction|growth during symbiotic interaction	https://github.com/geneontology/go-ontology/issues/20273				This term has been obsoleted because it represents an assay for viability, not a real biological process.		jl	2009-07-30T02:22:33Z		True	GO:0044153		biological_process											owl:Class	
GO:0045380	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0009621	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0031181	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0001625	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015588	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0047737	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0009053	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045075	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0032513	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045816	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0044261	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0044456	biolink:NamedThing	obsolete synapse part	OBSOLETE. Any constituent part of a synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell.	tmpzr1t_l9r_go_relaxed.owl	synaptic component				NIF_Subcellular:sao1784069613	Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.	GO:0045202				True			cellular_component											owl:Class	
GO:0008858	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0070812	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0075601	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0017037	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016044	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0005605	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1990954	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045351	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045356	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0071844	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1902302	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016481	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0051636	biolink:NamedThing	obsolete Gram-negative bacterial cell surface binding	OBSOLETE. Binding to a component on the surface of a Gram-negative bacterial cell.	tmpzr1t_l9r_go_relaxed.owl	Gram-negative bacterial cell surface binding|Gram-negative bacterium cell surface binding|Gram-negative bacterial binding|Gram-negative bacterium binding|binding to Gram-negative bacterium					This term was made obsolete because it is an unnecessary grouping term and was causing confusion.	GO:0003823|GO:0050829				True	GO:0008368		molecular_function											owl:Class	
GO:0003742	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0010576	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0097481	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0055030	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0001159	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0046388	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0010251	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0035105	biolink:NamedThing	obsolete sterol regulatory element binding protein import into nucleus	OBSOLETE. The transfer of a sterol regulatory element binding protein (SREBP) into the nucleus, across the nuclear membrane, in response to altered levels of one or more lipids. SREBPs are transcription factors that bind sterol regulatory elements (SREs), DNA motifs found in the promoters of target genes.	tmpzr1t_l9r_go_relaxed.owl	SREBP nuclear translocation|sterol depletion response, SREBP nuclear translocation|SREBP import into nucleus involved in sterol depletion response|SREBP import into nucleus|sterol regulatory element binding protein nuclear translocation involved in sterol depletion response|sterol depletion response, SREBP import into nucleus|sterol depletion response, sterol regulatory element binding protein nuclear translocation|sterol depletion response, sterol regulatory element binding protein import into nucleus|sterol regulatory element binding protein nuclear translocation|sterol regulatory element binding protein import into nucleus involved in sterol depletion response					The reason for obsoletion is that all proteins are imported into the nucleus via the same mechanism, so the import of individual proteins should be captured with extensions or by GO-CAM models.	GO:0006606|GO:0042306				True	GO:0006993		biological_process											owl:Class	
GO:0015598	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0007587	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0006674	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0071149	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052301	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0047984	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0031574	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016965	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0034262	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016956	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0003893	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0090097	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0072619	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052068	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0004887	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0002375	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0000790	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052287	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0005296	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0022621	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0031192	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0035031	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0031888	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0002740	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:2001182	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052304	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
OIO:hasExactSynonym	biolink:NamedThing	has_exact_synonym		tmpzr1t_l9r_go_relaxed.owl																									owl:AnnotationProperty	
GO:0004685	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016023	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052556	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0019223	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0002378	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016195	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0042533	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0018372	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0090525	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0005100	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0032360	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052274	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0050716	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0004431	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0030472	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0000355	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0005120	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0006300	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0048365	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0000273	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1990163	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0007330	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:2000188	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0001584	biolink:NamedThing	obsolete rhodopsin-like receptor activity	OBSOLETE. A G protein-coupled receptor that is structurally/functionally related to the rhodopsin receptor.	tmpzr1t_l9r_go_relaxed.owl	rhodopsin-like receptor activity|class A orphan receptor activity|Class A GPCR|Class A G protein coupled receptor|Class A G-protein coupled receptor					This term was made obsolete because it represents a gene product and is named based on protein features.					True	GO:0001620		molecular_function											owl:Class	
GO:0031936	biolink:NamedThing	obsolete negative regulation of chromatin silencing	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of chromatin silencing.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of chromatin silencing|negative regulation of heterochromatic silencing|down regulation of chromatin silencing|downregulation of chromatin silencing|loss of chromatin silencing|inhibition of chromatin silencing	https://github.com/geneontology/go-ontology/issues/22060				This term was obsoleted because it was too vague: regulation of chromatin (gene) silencing takes place via upstream signaling pathways.					True	GO:0006345		biological_process											owl:Class	
GO:0044122	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0048427	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0005087	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0030461	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0008434	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0075005	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1901240	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052348	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0043044	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045090	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1902658	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0006156	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0046407	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0042050	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:2000506	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0048276	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0006951	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0004606	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0005110	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0072480	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0019106	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1903309	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0018369	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0018821	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0005454	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0005468	biolink:NamedThing	obsolete small-molecule carrier or transporter	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	small-molecule carrier or transporter					This term was made obsolete because it does not provide a useful functional classification.	GO:0005215				True	GO:0005454|GO:0005453		molecular_function											owl:Class	
GO:0015178	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0001142	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1902449	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0000357	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015815	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0020029	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0044749	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0051313	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0051856	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045413	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0001663	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:2001203	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0044152	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0004221	biolink:NamedThing	obsolete ubiquitin thiolesterase activity	OBSOLETE. Catalysis of the reaction: ubiquitin C-terminal thioester + H2O = ubiquitin + a thiol.	tmpzr1t_l9r_go_relaxed.owl	ubiquitin C-terminal hydrolase activity|ubiquitin carboxy-terminal esterase activity|ubiquitin thiolesterase activity|ubiquitin thioesterase activity|ubiquitinyl hydrolase 1 activity|ubiquitin-C-terminal-thioester hydrolase activity|ubiquitin carboxy-terminal hydrolase activity				KEGG_REACTION:R02418|MetaCyc:UBIQUITIN-THIOLESTERASE-RXN	This term was made obsolete because this molecular function does not exist.	GO:0004843				True	GO:0008577		molecular_function											owl:Class	
GO:0001728	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0008060	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0018536	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1905077	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016194	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:2001179	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015509	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0003971	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045372	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0007145	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0071775	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0001176	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0019644	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0072408	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0001033	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0042231	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0008402	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0046393	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045379	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0072609	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0071156	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0005086	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0000784	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0005116	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0000503	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1901549	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0051855	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0072442	biolink:NamedThing	obsolete detection of stimulus involved in mitotic DNA replication checkpoint	OBSOLETE. The series of events in which information about whether DNA replication is complete is received and converted into a molecular signal, contributing to a mitotic DNA replication checkpoint.	tmpzr1t_l9r_go_relaxed.owl	S-M checkpoint sensor mechanism|mitotic DNA replication checkpoint sensor mechanism|sensing involved in mitotic DNA replication checkpoint|sensing involved in S-M checkpoint|detection of stimulus involved in S-M checkpoint|S-M checkpoint sensor process|mitotic DNA replication checkpoint sensor process	https://github.com/geneontology/go-ontology/issues/20976				This term was obsoleted because it corresponds to a molecular function.		mah	2010-12-08T05:12:49Z		True	GO:0072445		biological_process											owl:Class	
GO:0046840	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0008606	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0097679	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0048676	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0090247	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0043725	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0060555	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045318	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0046531	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0005083	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GOP:syngo_official_label	biolink:NamedThing	label approved by the SynGO project		tmpzr1t_l9r_go_relaxed.owl																									owl:AnnotationProperty	
GO:0001107	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0032191	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045118	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016909	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016141	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0150193	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0002216	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1902468	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0006830	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0007334	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015235	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0009393	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0044792	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015403	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:2000366	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:2000599	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0048305	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:2001184	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1902580	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0009817	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0072372	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0018987	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0006344	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0070829	biolink:NamedThing	obsolete heterochromatin maintenance	OBSOLETE. The chromatin organization process that preserves heterochromatin in a stable functional or structural state.	tmpzr1t_l9r_go_relaxed.owl	maintenance of heterochromatic silencing|heterochromatin maintenance involved in chromatin silencing|maintenance of chromatin silencing	https://github.com/geneontology/go-ontology/issues/22013				This term was obsoleted because it is redundant with heterochromatin organization and assembly terms.		mah	2009-07-23T04:14:49Z		True	GO:0070870|GO:0006344		biological_process											owl:Class	
GO:0052266	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016067	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0032313	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015177	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0004406	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0097312	biolink:NamedThing	obsolete bacterial biofilm matrix component	OBSOLETE. Any constituent part of the biofilm matrix, a structure lying external to bacterial cells. A biofilm is an aggregate of surface-associated bacteria, and the biofilm matrix is the envelope of polymeric substances that surrounds the bacteria.	tmpzr1t_l9r_go_relaxed.owl	biofilm matrix part					Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.	GO:0097311	pr	2012-05-24T11:22:56Z		True			cellular_component											owl:Class	
GO:0044801	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0072458	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0090457	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052371	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0018381	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0051605	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0008702	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0060103	biolink:NamedThing	obsolete collagen and cuticulin-based cuticle extracellular matrix part	OBSOLETE. Any constituent part of the collagen and cuticulin-based cuticle extracellular matrix, a collagen and cuticulin-based noncellular, multilayered structure that is synthesized by an underlying ectodermal (hypodermal) cell layer.	tmpzr1t_l9r_go_relaxed.owl						Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.	GO:0060102				True			cellular_component											owl:Class	
GO:0001075	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0046846	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0055098	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0010741	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015998	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0031191	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0043166	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015490	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1902451	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0120079	biolink:NamedThing	obsolete regulation of microfilament motor activity	OBSOLETE. Any process that modulates the frequency, rate or extent of microfilament motor activity.	tmpzr1t_l9r_go_relaxed.owl	regulation of actin-dependent ATPase activity|regulation of actin filament motor activity|regulation of actin-filament motor activity|regulation of actin-activated ATPase activity|regulation of myosin ATPase activity|regulation of muscle motor activity	https://github.com/geneontology/go-ontology/issues/20877				This term was obsoleted because it represents a molecular function.	GO:0140659	krc	2017-07-05T20:53:49Z		True	GO:1904621		biological_process											owl:Class	
GO:0061814	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0043788	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0042240	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0050751	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0030498	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0005748	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052423	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052382	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0044450	biolink:NamedThing	obsolete microtubule organizing center part	OBSOLETE. Any constituent part of a microtubule organizing center, a region in a eukaryotic cell, such as a centrosome or basal body, from which microtubules grow.	tmpzr1t_l9r_go_relaxed.owl	microtubule organizing centre component|MTOC component					Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.	GO:0005815				True			cellular_component											owl:Class	
GO:0042005	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0044422	biolink:NamedThing	obsolete organelle part	OBSOLETE. Any constituent part of an organelle, an organized structure of distinctive morphology and function. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, but excludes the plasma membrane.	tmpzr1t_l9r_go_relaxed.owl						Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.	GO:0043226				True			cellular_component											owl:Class	
GO:1902450	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0048182	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045452	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0051830	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0039539	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0043623	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0080087	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0017035	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0006514	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0000040	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0044117	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0019047	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0006758	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0001130	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0042927	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0030390	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0004597	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0035620	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1990126	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0003745	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0008598	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0044459	biolink:NamedThing	obsolete plasma membrane part	OBSOLETE. Any constituent part of the plasma membrane, the membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.	tmpzr1t_l9r_go_relaxed.owl						Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.	GO:0005886				True			cellular_component											owl:Class	
GO:1902739	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0070128	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052388	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0051806	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0050375	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0042456	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0051227	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0044429	biolink:NamedThing	obsolete mitochondrial part	OBSOLETE. Any constituent part of a mitochondrion, a semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.	tmpzr1t_l9r_go_relaxed.owl	mitochondrial subcomponent|mitochondrion component				NIF_Subcellular:sao666410040	Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.	GO:0005739				True			cellular_component											owl:Class	
GO:0018349	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0140016	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
NCBITaxon:38254	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl																										
GO:0005717	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0004293	biolink:NamedThing	obsolete tissue kallikrein activity	OBSOLETE. Catalysis of the preferential cleavage of Arg-Xaa bonds in small molecule substrates. Highly selective action to release kallidin (lysyl-bradykinin) from kininogen involves hydrolysis of Met-Xaa or Leu-Xaa. The rat enzyme is unusual in liberating bradykinin directly from autologous kininogens by cleavage at two Arg-Xaa bonds.	tmpzr1t_l9r_go_relaxed.owl	padutin|bradykininogenase|urinary kallikrein|glandular kallikrein activity|callicrein|tissue kallikrein activity|kallidinogenase|pancreatic kallikrein|onokrein P|salivary kallikrein|urokallikrein|padreatin|submandibular kallikrein|dilminal D|glumorin|kidney kallikrein|submaxillary kallikrein|depot-padutin|kininogenin activity|kininogenase			GO:0004252		This term was made obsolete because it represents a gene product.					True	GO:0004279		molecular_function											owl:Class	
GO:0048739	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0075125	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0043355	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1990510	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0036142	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0004981	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0033267	biolink:NamedThing	obsolete axon part	OBSOLETE. A part of an axon, a cell projection of a neuron.	tmpzr1t_l9r_go_relaxed.owl					NIF_Subcellular:sao280355188	Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.	GO:0030424				True			cellular_component											owl:Class	
GO:0046991	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045524	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0006440	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0051317	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0032860	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:2001201	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0090003	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0072403	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0001538	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0009981	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052069	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0075716	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0006137	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0004646	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0010281	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0097249	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0044709	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045350	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0051690	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1990289	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052004	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0031188	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015287	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0032128	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0043339	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0033155	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1904264	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0008971	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0044236	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0048429	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0005659	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0070491	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0072358	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0048413	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0070872	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0006827	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1990035	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0000358	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0007404	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0042172	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0000442	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052259	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0048417	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0033216	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1903274	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0044428	biolink:NamedThing	obsolete nuclear part	OBSOLETE. Any constituent part of the nucleus, a membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated.	tmpzr1t_l9r_go_relaxed.owl	nuclear subcomponent|nucleus component				NIF_Subcellular:sao1499850686	Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.	GO:0005634				True			cellular_component											owl:Class	
NCBITaxon:6237	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl																										
GO:0006262	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0044439	biolink:NamedThing	obsolete peroxisomal part	OBSOLETE. Any constituent part of a peroxisome, a small, membrane-bounded organelle that uses dioxygen (O2) to oxidize organic molecules; contains some enzymes that produce and others that degrade hydrogen peroxide (H2O2).	tmpzr1t_l9r_go_relaxed.owl	peroxisome component					Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.	GO:0005777				True			cellular_component											owl:Class	
GO:0019839	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0075126	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0004701	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0050754	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052061	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045418	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1902827	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0051662	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1990944	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0019067	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0030349	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0033136	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0055132	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0009928	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
NCBITaxon:5878	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl																										
GO:0090061	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0042737	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0033213	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0003869	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1900455	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0070870	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0005317	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0030630	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0090467	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0044124	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0030765	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052526	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0061489	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0044449	biolink:NamedThing	obsolete contractile fiber part	OBSOLETE. Any constituent part of a contractile fiber, a fiber composed of actin, myosin, and associated proteins, found in cells of smooth or striated muscle.	tmpzr1t_l9r_go_relaxed.owl	contractile fibre component|muscle fiber component|muscle fibre component					Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.	GO:0043292				True			cellular_component											owl:Class	
GO:0048748	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0051243	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1990707	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0004440	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0042234	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0075059	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0007466	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0048110	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0030360	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0019175	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0019946	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0019192	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0042503	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0000021	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0060553	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0044434	biolink:NamedThing	obsolete chloroplast part	OBSOLETE. Any constituent part of a chloroplast, a chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.	tmpzr1t_l9r_go_relaxed.owl						Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.	GO:0009507				True			cellular_component											owl:Class	
GO:0098587	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0044443	biolink:NamedThing	obsolete pilus part	OBSOLETE. Any constituent part of a pilus, a proteinaceous hair-like appendage on the surface of bacteria ranging from 2-8 nm in diameter.	tmpzr1t_l9r_go_relaxed.owl	fimbrium component|fimbrial part|pilus component					Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.	GO:0009289				True			cellular_component											owl:Class	
GO:0005554	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0075007	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0001200	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015457	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0044366	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0008394	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0042829	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016283	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0030470	biolink:NamedThing	obsolete spore germination (sensu Fungi)	OBSOLETE. Process of breakdown or opening of the spore-containing structure, modification of the spore wall, and resumption of growth of the spore. As in, but not restricted to, the fungi (Fungi, ncbi_taxonomy_id:4751).	tmpzr1t_l9r_go_relaxed.owl	germination (sensu Saccharomyces)|spore germination (sensu Fungi)			GO:0009847		This term was made obsolete because a sensu term was not needed.					True	GO:0007153		biological_process											owl:Class	
GO:0090622	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0089712	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1990283	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015266	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0030385	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0000998	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0018368	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
NCBITaxon:10090	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl																										
GO:0008723	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015978	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0048430	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0000143	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0007544	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0005860	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0046675	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015396	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0044039	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0022816	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0009362	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015201	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016654	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0004002	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0048129	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0001124	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0032314	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0072621	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0012503	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0044435	biolink:NamedThing	obsolete plastid part	OBSOLETE. Any constituent part of a plastid, a member of a family of organelles found in the cytoplasm of plants and some protists, which are membrane-bounded and contain DNA. Plant plastids develop from a common type, the proplastid.	tmpzr1t_l9r_go_relaxed.owl						Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.	GO:0009536				True			cellular_component											owl:Class	
GO:0071789	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0004770	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0008588	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0018346	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0044427	biolink:NamedThing	obsolete chromosomal part	OBSOLETE. Any constituent part of a chromosome, a structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information.	tmpzr1t_l9r_go_relaxed.owl	chromosome part|chromosome component|chromosomal component					Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.	GO:0005694				True			cellular_component											owl:Class	
GO:0044116	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0042872	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0008357	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0034448	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0031197	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0002818	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0150162	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1902540	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045399	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0004863	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:2001183	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0042507	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0044432	biolink:NamedThing	obsolete endoplasmic reticulum part	OBSOLETE. Any constituent part of the endoplasmic reticulum, the irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae.	tmpzr1t_l9r_go_relaxed.owl	ER component					Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.	GO:0005783				True			cellular_component											owl:Class	
GO:0004199	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
NCBITaxon:33630	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl																										
GO:0052566	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0044268	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0004724	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0005379	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0050705	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0051441	biolink:NamedThing	obsolete positive regulation of ubiquitin-protein ligase activity involved in meiotic cell cycle	OBSOLETE. Any process that activates, maintains or increases the rate of ubiquitin ligase activity during the meiotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl	stimulation of ubiquitin ligase activity during meiotic cell cycle|anaphase promoting complex activation during meiotic cell cycle|meiotic SCF complex activator|up regulation of ubiquitin ligase activity during meiotic cell cycle|anaphase-promoting complex activation during meiotic cell cycle|activation of ubiquitin ligase activity of anaphase promoting complex during meiotic cell cycle|activation of anaphase-promoting complex activity involved in meiotic cell cycle|meiotic anaphase-promoting complex activator|activation of ubiquitin ligase activity of APC during meiotic cell cycle|meiotic anaphase promoting complex activator|APC activation during meiotic cell cycle|activation of anaphase-promoting complex activity during meiotic cell cycle|meiotic APC activation|positive regulation of ubiquitin-protein ligase activity during meiotic cell cycle|positive regulation of ubiquitin ligase activity during meiotic cell cycle|activation of ubiquitin ligase activity during meiotic cell cycle|activation of ubiquitin ligase activity of anaphase-promoting complex during meiotic cell cycle|up-regulation of ubiquitin ligase activity during meiotic cell cycle|meiotic APC activator|upregulation of ubiquitin ligase activity during meiotic cell cycle|meiotic ubiquitin ligase activator|meiotic anaphase promoting complex activation	https://github.com/geneontology/go-ontology/issues/15196				This term was obsoleted because it should be captured as a GO-CAM model.					True	GO:0051487		biological_process											owl:Class	
GO:0072604	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0000370	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045408	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0007262	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0034259	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0070969	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0036264	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0009096	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0005284	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0019378	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0005380	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0006985	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016276	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052397	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0072419	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045245	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1902409	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045396	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1902881	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1990886	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0090476	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0008014	biolink:NamedThing	obsolete calcium-dependent cell adhesion molecule activity	OBSOLETE. A calcium-dependent cell adhesion protein (type I membrane protein) that interacts in a homophilic manner in cell-cell interactions.	tmpzr1t_l9r_go_relaxed.owl	calcium-dependent cell adhesion molecule activity|cadherin					This term was made obsolete because it represents a gene product.	GO:0016021|GO:0016339|GO:0005515				True	GO:0001538		molecular_function											owl:Class	
GO:0001210	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016951	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0001071	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016178	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016510	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
NCBITaxon:9606	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl																										
GO:0003766	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015300	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0090509	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0042348	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0005926	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0044431	biolink:NamedThing	obsolete Golgi apparatus part	OBSOLETE. Any constituent part of the Golgi apparatus, a compound membranous cytoplasmic organelle of eukaryotic cells, consisting of flattened, ribosome-free vesicles arranged in a more or less regular stack.	tmpzr1t_l9r_go_relaxed.owl	Golgi component|Golgi subcomponent				NIF_Subcellular:sao624292949	Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.	GO:0005794				True			cellular_component											owl:Class	
GO:0008850	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0008848	biolink:NamedThing	obsolete enterobactin synthetase	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	nonribosomal peptide synthetase|enterochelin synthetase activity|enterobactin synthetase			GO:0009239		This term was made obsolete because it represents a process rather than a function.					True	GO:0008850		molecular_function											owl:Class	
GO:0019861	biolink:NamedThing	obsolete flagellum	OBSOLETE. Long whiplike or feathery structures borne either singly or in groups by the motile cells of many bacteria and unicellular eukaryotes and by the motile male gametes of many eukaryotic organisms, which propel the cell through a liquid medium.	tmpzr1t_l9r_go_relaxed.owl	flagellum				Wikipedia:Flagellum	This term was made obsolete because it was an unnecessary grouping term. Eukaryotic flagella were deemed to be equivalent to cilia and merged, so the only remaining child to this term was 'bacterial-type flagellum ; GO:0009288'.	GO:0005929|GO:0009288				True	GO:0008223		cellular_component											owl:Class	
GO:0009870	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0003741	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0072478	biolink:NamedThing	obsolete detection of stimulus involved in mitotic spindle assembly checkpoint	OBSOLETE. The series of events in which information about whether the spindle is correctly assembled, and chromosomes are attached to the spindle, is received and converted into a molecular signal, contributing to a mitotic cell cycle spindle assembly checkpoint.	tmpzr1t_l9r_go_relaxed.owl	mitotic cell cycle spindle assembly checkpoint sensor mechanism|stimulus detection involved in SAC-independent checkpoint|mitotic cell cycle spindle assembly checkpoint sensor process|stimulus sensing involved in SAC-independent checkpoint|stimulus detection involved in DMA1-dependent checkpoint|sensing involved in mitotic cell cycle spindle assembly checkpoint|detection of stimulus involved in Dma1-dependent checkpoint|perception of stimulus involved in DMA1-dependent checkpoint|perception of stimulus involved in SAC-independent checkpoint|detection of stimulus involved in SAC-independent checkpoint|detection of stimulus involved in mitotic cell cycle spindle assembly checkpoint|stimulus sensing involved in DMA1-dependent checkpoint	https://github.com/geneontology/go-ontology/issues/20976				This term was obsoleted because it corresponds to a molecular function.		mah	2010-12-09T12:11:18Z		True	GO:1902419		biological_process											owl:Class	
GO:0048063	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0042486	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0005339	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0034065	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0046733	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0006151	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0098748	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0048431	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015359	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0097549	biolink:NamedThing	obsolete chromatin organization involved in negative regulation of transcription	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of transcription by chromatin organization.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of transcription from Pol II promoter by histone modification|negative regulation of transcription from RNA polymerase II promoter by histone modification|negative regulation of global transcription from Pol II promoter by histone modification|negative regulation of gene-specific transcription from RNA polymerase II promoter by histone modification|negative regulation of transcription from RNA polymerase II promoter, global by histone modification|negative regulation of transcription by chromatin organization	https://github.com/geneontology/go-ontology/issues/22041				This term was obsoleted because these it was redundant with other terms: heterochromatin assembly and negative regulation of gene expression, epigenetic.		pr	2014-01-22T08:20:50Z		True	GO:1903758		biological_process											owl:Class	
GO:0032316	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0000996	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0030693	biolink:NamedThing	obsolete caspase activity	OBSOLETE. Catalysis of the hydrolysis of a peptide bond on the carboxyl side of an aspartate residue.	tmpzr1t_l9r_go_relaxed.owl	caspase-7 activity|caspase-1 activity|caspase-10 activity|caspase-4 activity|caspase-6 activity|caspase-9 activity|caspase-3 activity|caspase activity|caspase-8 activity|caspase-2 activity|effector caspase activity|signaling (initiator) caspase activity|caspase-5 activity			GO:0004197		This term was made obsolete because it represents a gene product.					True	GO:0004199		molecular_function											owl:Class	
GO:0000903	biolink:NamedThing	obsolete regulation of cell shape during vegetative growth phase	OBSOLETE. Any process that modulates the surface configuration of a cell during the vegetative growth phase. The vegetative growth phase is the growth phase during which single celled organisms reproduce by budding or other asexual methods.	tmpzr1t_l9r_go_relaxed.owl	regulation of cell morphogenesis during vegetative growth phase|cell morphogenesis during vegetative growth phase|cellular morphogenesis during vegetative growth					The reason for obsoletion is that biological phases should be captured as extensions.					True	GO:0090061		biological_process											owl:Class	
NCBITaxon:58024	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl																										
GO:0006416	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0050725	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0033589	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0001009	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0009929	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0001022	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0048424	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0033742	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0019950	biolink:NamedThing	obsolete SMT3-dependent protein catabolic process	OBSOLETE. The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by covalent attachment of the ubiquitin-like protein SMT3 to the target protein.	tmpzr1t_l9r_go_relaxed.owl	SMT3-dependent protein catabolism|SMT3-dependent protein breakdown|SMT3-dependent protein degradation					See issue #21890. SMT3 protein mod is sumoylation and does not always lead to degradation.					True	GO:0019946		biological_process											owl:Class	
GO:0008895	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0005098	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0044453	biolink:NamedThing	obsolete nuclear membrane part	OBSOLETE. Any constituent part of the nuclear membrane, the envelope that surrounds the nucleus of eukaryotic cells.	tmpzr1t_l9r_go_relaxed.owl						Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.	GO:0031965				True			cellular_component											owl:Class	
GO:0018086	biolink:NamedThing	obsolete alanine racemization	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	alanine racemization					This term was made obsolete because it was replaced with more appropriate terms.	GO:0019122				True	GO:0018368		biological_process											owl:Class	
GO:0001904	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
RO:0002091	biolink:NamedThing	starts_during		tmpzr1t_l9r_go_relaxed.owl					RO:0002091|RO:0002091									external|external									starts_during|starts_during		owl:ObjectProperty	
BFO:0000066	biolink:NamedThing	occurs in		tmpzr1t_l9r_go_relaxed.owl					BFO:0000066|BFO:0000066									external|external									occurs_in|occurs_in		owl:ObjectProperty	
GO:0046261	biolink:NamedThing	obsolete 4-nitrotoluene biosynthetic process	OBSOLETE. The chemical reactions and pathways resulting in the formation of 4-nitrotoluene, 1-methyl-4-nitrobenzene.	tmpzr1t_l9r_go_relaxed.owl	4-nitrotoluene biosynthesis|4-nitrotoluene anabolism|4-nitrotoluene biosynthetic process|4-nitrotoluene formation|4NT biosynthetic process|4NT biosynthesis|4-nitrotoluene synthesis			GO:0019257		This term was made obsolete because 4-nitrotoluene is not synthesized by living organisms, and GO does not cover non-biological processes.					True			biological_process											owl:Class	
GO:0001063	biolink:NamedThing	obsolete plastid PEP-B RNA polymerase activity	OBSOLETE. Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template that contains a plastid PEP-B RNA polymerase II specific promoter to direct initiation and catalyses DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/16738		GO:0003899		This term was obsoleted because the activity is the same as its parent.		krc	2010-10-19T03:46:46Z		True			molecular_function											owl:Class	
GO:1903695	biolink:NamedThing	obsolete MAPK cascade involved in ascospore formation	OBSOLETE. Any MAPK cascade that is involved in ascospore formation.	tmpzr1t_l9r_go_relaxed.owl	MAPK signaling involved in ascospore formation|MAP kinase cascade involved in ascospore formation|ERK/MAPK cascade involved in ascospore formation|MAPK signal transduction involved in ascospore formation|mitogen-activated protein kinase cascade involved in ascospore formation|MAPKKK cascade during sporulation involved in ascospore biosynthesis|mitogen-activated protein kinase cascade involved in ascospore biosynthesis|MAPK signal transduction involved in ascospore biosynthesis|ERK/MAPK cascade involved in ascospore biosynthesis|MAPKKK cascade involved in ascospore formation|MAPKKK cascade during sporulation involved in ascospore formation|MAPK signalling involved in ascospore biosynthesis|MAPK signalling involved in ascospore formation|MAP kinase kinase kinase cascade involved in ascospore biosynthesis|MAPK signaling involved in ascospore biosynthesis|MAP kinase kinase kinase cascade involved in ascospore formation|MAPKKK cascade involved in ascospore biosynthesis|MAP kinase cascade involved in ascospore biosynthesis|MAPK cascade involved in ascospore biosynthesis	https://github.com/geneontology/go-ontology/issues/14323				This term was obsoleted because it represents a GO-CAM model.		al	2014-12-02T22:09:18Z		True			biological_process											owl:Class	
GO:0004249	biolink:NamedThing	obsolete stromelysin 3 activity	OBSOLETE. Was not defined before being made obsolete.	tmpzr1t_l9r_go_relaxed.owl	MMP-11|stromelysin 3 activity|matrix metalloproteinase 11			GO:0004222		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0042027	biolink:NamedThing	obsolete cyclophilin-type peptidyl-prolyl cis-trans isomerase activity	OBSOLETE. Catalysis of the reaction: peptidylproline (omega=180) = peptidylproline (omega=0).	tmpzr1t_l9r_go_relaxed.owl	cyclophilin-type peptidyl-prolyl cis-trans isomerase activity					This term was made obsolete because it is contains gene product specific characteristics.	GO:0003755				True			molecular_function											owl:Class	
GO:0019940	biolink:NamedThing	obsolete SUMO-dependent protein catabolic process	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	SUMO-dependent protein breakdown|SUMO-dependent protein degradation|SUMO-dependent protein catabolic process|SUMO-dependent protein catabolism					This term was made obsolete because it does not reflect an accurate biological process, as sumoylation of a protein does not lead to catabolism of that protein.	GO:0016926|GO:0016925				True			biological_process											owl:Class	
GO:0052219	biolink:NamedThing	obsolete negative energy taxis in environment of other organism involved in symbiotic interaction	OBSOLETE. The directed movement of a motile cell or organism on, within or near a second organism towards a lower level of a physical stimulus involved in energy generation, such as light, oxygen, and oxidizable substrates, where the two organisms are in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	negative energy taxis in response to environment of other organism|negative energy taxis in environment of other organism during symbiotic interaction					This term was obsoleted because it represents both a process and a location.					True			biological_process											owl:Class	
GO:0008085	biolink:NamedThing	obsolete phototransduction, visible light, light adaptation	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	phototransduction, visible light, light adaptation					This term was made obsolete because the term name is ambiguous.	GO:0007602				True			biological_process											owl:Class	
GO:0001317	biolink:NamedThing	obsolete accumulation of oxidatively modified proteins involved in replicative cell aging	OBSOLETE. Accumulation of proteins that have undergone reactions with reactive oxygen species in aging dividing cells and exhibit modifications such as increased protein carbonyl content, oxidized methionine, protein hydrophobicity, and cross-linking.	tmpzr1t_l9r_go_relaxed.owl	accumulation of oxidatively modified proteins during replicative cell aging|accumulation of oxidatively modified proteins during replicative cell ageing	https://github.com/geneontology/go-ontology/issues/20007				This term was obsoleted because it represents an assay, not a true biological process.					True			biological_process											owl:Class	
GO:1903290	biolink:NamedThing	obsolete negative regulation of ATP catabolic process	OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of ATP catabolic process.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of ATP catabolism|downregulation of ATP degradation|inhibition of ATP hydrolysis|inhibition of ATP catabolism|downregulation of ATP catabolism|negative regulation of ATP breakdown|down regulation of ATP catabolic process|negative regulation of ATP hydrolysis|inhibition of ATP breakdown|inhibition of ATP catabolic process|down regulation of ATP breakdown|downregulation of ATP hydrolysis|down-regulation of ATP hydrolysis|down regulation of ATP catabolism|downregulation of ATP breakdown|down-regulation of ATP breakdown|inhibition of ATP degradation|down regulation of ATP hydrolysis|negative regulation of ATP degradation|down regulation of ATP degradation|downregulation of ATP catabolic process|down-regulation of ATP catabolic process|down-regulation of ATP degradation|negative regulation of ATP catabolism					The reason for making this term obsolete is that it gets misused in cases where phosphates are simply being removed from a small molecule. We found no cases where these molecules genuinely underwent catabolism.	GO:0032780	rl	2014-08-11T14:36:47Z		True			biological_process											owl:Class	
GO:0008155	biolink:NamedThing	obsolete larval behavior (sensu Drosophila)	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	larval behavior (sensu Drosophila)			GO:0030537		This term was made obsolete because there is no clear difference between the sensu Drosophila term and the generic term.					True			biological_process											owl:Class	
GO:0042804	biolink:NamedThing	obsolete protein homooligomerization activity	OBSOLETE. Interacting selectively with identical proteins to form a homooligomer.	tmpzr1t_l9r_go_relaxed.owl	protein homooligomerization activity|oligomerization activity			GO:0051260		This term was made obsolete because it represents a biological process.					True			molecular_function											owl:Class	
GO:0006118	biolink:NamedThing	obsolete electron transport	OBSOLETE. The transport of electrons from an electron donor to an electron acceptor.	tmpzr1t_l9r_go_relaxed.owl	electron transfer|oxidized glutathione reduction|6-phosphofructokinase reduction|dihydropteridine reduction|dihydrobiopterin reduction|other pathways of electron transport|dihydrolipoamide reduction|electron transport|protein-disulfide reduction|dihydrolipoylprotein reduction					This term was made obsolete because it describes a molecular function.	GO:0016491|GO:0022904				True			biological_process											owl:Class	
GO:0075332	biolink:NamedThing	obsolete modulation by host of symbiont adenylate cyclase-mediated signal transduction	OBSOLETE. Any process in which the host organism modulates the frequency, rate or extent of adenylate cyclase-mediated signal transduction in the symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl						The reason for obsoletion is that there is no evidence that the host can modulate or regulate a symbiont's signal transduction pathway.					True			biological_process											owl:Class	
GO:1903149	biolink:NamedThing	obsolete adenine transmembrane transporter activity involved in adenine import into cell	OBSOLETE. Any adenine transmembrane transporter activity that is involved in adenine import into cell.	tmpzr1t_l9r_go_relaxed.owl	adenine transmembrane transporter activity involved in adenine import into cell					This term was obsoleted at the TermGenie Gatekeeper stage.		dos	2014-07-09T11:55:30Z		True			molecular_function											owl:Class	
GO:1904921	biolink:NamedThing	obsolete negative regulation of MAPK cascade involved in axon regeneration	OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of MAPK cascade involved in axon regeneration.	tmpzr1t_l9r_go_relaxed.owl	downregulation of MAPKKK cascade during sporulation involved in axon regeneration|down-regulation of MAPK signal transduction involved in axon regeneration|down-regulation of MAPK signalling involved in axon regeneration|downregulation of ERK/MAPK cascade involved in axon regeneration|downregulation of MAP kinase kinase kinase cascade involved in axon regeneration|down-regulation of MAPK cascade involved in axon regeneration|inhibition of MAPKKK cascade during sporulation involved in axon regeneration|down-regulation of ERK/MAPK cascade involved in axon regeneration|downregulation of MAPKKK cascade involved in axon regeneration|down regulation of mitogen-activated protein kinase cascade involved in axon regeneration|negative regulation of MAPK signaling involved in axon regeneration|negative regulation of MAPK signal transduction involved in axon regeneration|inhibition of mitogen-activated protein kinase cascade involved in axon regeneration|negative regulation of MAPKKK cascade during sporulation involved in axon regeneration|downregulation of MAP kinase cascade involved in axon regeneration|downregulation of MAPK signalling involved in axon regeneration|negative regulation of ERK/MAPK cascade involved in axon regeneration|down regulation of ERK/MAPK cascade involved in axon regeneration|downregulation of MAPK signal transduction involved in axon regeneration|down regulation of MAPK signaling involved in axon regeneration|negative regulation of MAPK signalling involved in axon regeneration|negative regulation of mitogen-activated protein kinase cascade involved in axon regeneration|inhibition of MAP kinase kinase kinase cascade involved in axon regeneration|inhibition of ERK/MAPK cascade involved in axon regeneration|negative regulation of MAP kinase cascade involved in axon regeneration|inhibition of MAPK signalling involved in axon regeneration|inhibition of MAP kinase cascade involved in axon regeneration|downregulation of MAPK signaling involved in axon regeneration|down-regulation of MAP kinase kinase kinase cascade involved in axon regeneration|downregulation of mitogen-activated protein kinase cascade involved in axon regeneration|down regulation of MAPK signalling involved in axon regeneration|downregulation of MAPK cascade involved in axon regeneration|down regulation of MAP kinase cascade involved in axon regeneration|down-regulation of mitogen-activated protein kinase cascade involved in axon regeneration|down-regulation of MAPKKK cascade during sporulation involved in axon regeneration|inhibition of MAPKKK cascade involved in axon regeneration|negative regulation of MAPKKK cascade involved in axon regeneration|down regulation of MAPKKK cascade during sporulation involved in axon regeneration|down regulation of MAPKKK cascade involved in axon regeneration|inhibition of MAPK signal transduction involved in axon regeneration|down regulation of MAPK signal transduction involved in axon regeneration|inhibition of MAPK cascade involved in axon regeneration|negative regulation of MAP kinase kinase kinase cascade involved in axon regeneration|down regulation of MAP kinase kinase kinase cascade involved in axon regeneration|inhibition of MAPK signaling involved in axon regeneration|down regulation of MAPK cascade involved in axon regeneration|down-regulation of MAPKKK cascade involved in axon regeneration|down-regulation of MAP kinase cascade involved in axon regeneration|down-regulation of MAPK signaling involved in axon regeneration	https://github.com/geneontology/go-ontology/issues/14323				This term was obsoleted because it represents a GO-CAM model.		kmv	2016-01-25T17:03:42Z		True			biological_process											owl:Class	
GO:0030821	biolink:NamedThing	obsolete negative regulation of cAMP catabolic process	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate).	tmpzr1t_l9r_go_relaxed.owl	negative regulation of adenosine 3',5'-cyclophosphate catabolic process|negative regulation of cAMP catabolism|inhibition of cAMP catabolic process|negative regulation of cyclic AMP catabolic process|negative regulation of 3',5' cAMP catabolic process|negative regulation of 3',5'-cAMP catabolic process|negative regulation of adenosine 3',5'-cyclophosphate catabolism|negative regulation of cAMP breakdown|downregulation of cAMP catabolic process|down-regulation of cAMP catabolic process|down regulation of cAMP catabolic process|negative regulation of 3',5'-cAMP catabolism|negative regulation of cyclic AMP catabolism|negative regulation of cAMP degradation|negative regulation of 3',5' cAMP catabolism					The reason for obsoletion is that this term represents the regulation of a signaling pathway, not regulation of metabolism.					True			biological_process											owl:Class	
GO:0052108	biolink:NamedThing	obsolete growth or development of symbiont during interaction with host	OBSOLETE. The increase in size or mass of an organism, or the progression of an organism from an initial condition to a later condition, occurring in, on or near the exterior of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	growth or development of organism in response to host|growth or development of symbiont during interaction with host|growth or development of organism during interaction with host					This term was made obsolete because it contained a conjunction (or).	GO:0051701|GO:0044111				True			biological_process											owl:Class	
GO:0046973	biolink:NamedThing	obsolete histone lysine N-methyltransferase activity (H3-K24 specific)	OBSOLETE. Catalysis of the addition of a methyl group onto lysine at position 24 of the histone H3 protein.	tmpzr1t_l9r_go_relaxed.owl	histone lysine N-methyltransferase activity (H3-K24 specific)					This term was made obsolete because there is no lysine at position 24 of histone H3.	GO:0042800				True			molecular_function											owl:Class	
GO:0030826	biolink:NamedThing	obsolete regulation of cGMP biosynthetic process	OBSOLETE. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cGMP.	tmpzr1t_l9r_go_relaxed.owl	regulation of cGMP synthesis|regulation of cGMP biosynthesis|regulation of cGMP anabolism|regulation of cGMP formation					The reason for obsoletion is that this term represents the regulation of a signaling pathway, not regulation of metabolism.					True			biological_process											owl:Class	
GO:1900083	biolink:NamedThing	obsolete regulation of Sertoli cell proliferation	OBSOLETE. Any process that modulates the frequency, rate or extent of Sertoli cell proliferation.	tmpzr1t_l9r_go_relaxed.owl	regulation of Sertoli cell proliferation					This term was obsoleted at the TermGenie Gatekeeper stage.		pr	2012-02-02T03:10:50Z		True			biological_process											owl:Class	
GO:0001076	biolink:NamedThing	obsolete transcription factor activity, RNA polymerase II transcription factor binding	OBSOLETE. Binding to an RNA polymerase II transcription factor, which may be a single protein or a complex, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well.	tmpzr1t_l9r_go_relaxed.owl	RNA polymerase II transcription factor binding transcription factor activity	https://github.com/geneontology/go-ontology/issues/16053				The reason for obsoletion is that this concept is partly covered by other concepts in the ontology and usage has been inconsistent.	GO:0061629|GO:0140110	krc	2010-10-22T02:49:32Z		True			molecular_function											owl:Class	
GO:0009619	biolink:NamedThing	obsolete resistance to pathogenic bacteria	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	resistance to pathogenic bacteria			GO:0009617		This term was made obsolete because 'resistance' implies a phenotype rather than a biological process.					True			biological_process											owl:Class	
GO:0048037	biolink:NamedThing	obsolete cofactor binding	OBSOLETE. Binding to a cofactor, a substance that is required for the activity of an enzyme or other protein. Cofactors may be inorganic, such as the metal atoms zinc, iron, and copper in certain forms, or organic, in which case they are referred to as coenzymes. Cofactors may either be bound tightly to active sites or bind loosely with the substrate.	tmpzr1t_l9r_go_relaxed.owl						1. Making inferences in GO about compounds based on the cofactor role curated by ChEBI creates relationships that are not always true which violates ontological principles for GO; therefore we will cease making these inferences. 2. It is not meaningful to group binding interactions that are not all chemically related by the fact that they may be used as a cofactor.					True			molecular_function											owl:Class	
GO:0075346	biolink:NamedThing	obsolete modification by symbiont of host protein by ubiquitination	OBSOLETE. The process in which an organism adds one or more ubiquitin groups to a protein of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	modification by symbiont of host protein by ubiquitylation|modification by symbiont of host protein by ubiquitinylation	https://github.com/geneontology/go-ontology/issues/21469				This term was obsoleted because it represents a molecular function.					True			biological_process											owl:Class	
GO:0061465	biolink:NamedThing	obsolete plasma membrane part of hemidesmosome	OBSOLETE. The part of the plasma membrane that contributes to the structure of a hemidesmosome.	tmpzr1t_l9r_go_relaxed.owl						The reasons for obsoletion are that (1) this term does not have any gene products associated with them and (2) it can be represented as a GO-CAM.		dph	2012-10-19T13:47:25Z		True			cellular_component											owl:Class	
GO:0100068	biolink:NamedThing	obsolete positive regulation of pyrimidine-containing compound salvage by transcription from RNA polymerase II promoter	OBSOLETE. Any transcription from RNA polymerase II promoter process that positively regulates pyrimidine-containing compound salvage.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it represents a GO-CAM model.		cjm	2015-04-02T04:13:19Z		True			biological_process											owl:Class	
GO:0015262	biolink:NamedThing	obsolete taurine channel activity	OBSOLETE. This term was not defined before being made obsolete.	tmpzr1t_l9r_go_relaxed.owl	taurine channel activity					This term was made obsolete because this solute is transported by an active transporter rather than a channel.					True			molecular_function											owl:Class	
GO:0052454	biolink:NamedThing	obsolete modulation by organism of symbiont jasmonic acid-mediated defense response	OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of the jasmonic acid-mediated defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	modulation by organism of symbiont jasmonic acid-mediated defense response|modulation by organism of symbiont JA-mediated defense response					This term was made obsolete because it does not represent a real biological process.					True			biological_process											owl:Class	
GO:0044800	biolink:NamedThing	obsolete multi-organism membrane fusion	OBSOLETE. The membrane organization process that joins two lipid bilayers to form a single membrane, involving more than one organism.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/21459				This term was obsoleted because it is not a biologically meaningful grouping class.		jl	2013-09-10T15:06:11Z		True			biological_process											owl:Class	
GO:0005650	biolink:NamedThing	obsolete importin, alpha-subunit transport factor	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	importin, alpha-subunit transport factor|CAS					This term was made obsolete because it represents a single gene product and not a complex.	GO:0005634|GO:0005643|GO:0005737				True			cellular_component											owl:Class	
GO:0030818	biolink:NamedThing	obsolete negative regulation of cAMP biosynthetic process	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate).	tmpzr1t_l9r_go_relaxed.owl	negative regulation of cyclic AMP biosynthetic process|negative regulation of adenosine 3',5'-cyclophosphate biosynthesis|negative regulation of cAMP anabolism|downregulation of cAMP biosynthetic process|down regulation of cAMP biosynthetic process|negative regulation of adenosine 3',5'-cyclophosphate biosynthetic process|negative regulation of 3',5'-cAMP biosynthesis|inhibition of cAMP biosynthetic process|negative regulation of cAMP synthesis|negative regulation of cAMP formation|negative regulation of cAMP biosynthesis|down-regulation of cAMP biosynthetic process|negative regulation of 3',5'-cAMP biosynthetic process|negative regulation of cyclic AMP biosynthesis|negative regulation of 3',5' cAMP biosynthetic process|negative regulation of 3',5' cAMP biosynthesis	https://github.com/geneontology/go-ontology/issues/14718				The reason for obsoletion is that the term represents a molecular function.					True			biological_process											owl:Class	
GO:1901294	biolink:NamedThing	obsolete negative regulation of SREBP signaling pathway by negative regulation of DNA binding	OBSOLETE. Negative regulation of DNA binding that results in negative regulation of a SREBP signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of SREBP-mediated signaling pathway by down regulation of DNA binding|negative regulation of SREBP signaling pathway by downregulation of DNA binding|negative regulation of SREBP-mediated signaling pathway by down-regulation of DNA binding|negative regulation of SREBP-mediated signaling pathway by inhibition of DNA binding|negative regulation of SREBP-mediated signaling pathway by downregulation of DNA binding|negative regulation of SREBP signaling pathway by down regulation of DNA binding|negative regulation of SREBP-mediated signalling pathway by inhibition of DNA binding|negative regulation of SREBP-mediated signalling pathway by downregulation of DNA binding|negative regulation of SREBP-mediated signaling pathway by negative regulation of DNA binding|negative regulation of SREBP-mediated signalling pathway by down-regulation of DNA binding|negative regulation of SREBP-mediated signalling pathway by down regulation of DNA binding|negative regulation of SREBP signaling pathway by down-regulation of DNA binding|inhibition of SREBP-dependent transcription by blocking DNA binding|negative regulation of SREBP signaling pathway by inhibition of DNA binding|negative regulation of SREBP-mediated signalling pathway by negative regulation of DNA binding					The reason for obsoletion is that this term should be represented by a GO-CAM model.		bf	2012-08-20T14:11:03Z		True			biological_process											owl:Class	
GO:0030535	biolink:NamedThing	obsolete adult feeding behavior (sensu Insecta)	OBSOLETE. Feeding behavior in a fully developed and mature organism, as described in insects.	tmpzr1t_l9r_go_relaxed.owl	adult feeding behavior (sensu Insecta)			GO:0008343		This term was made obsolete because there is no clear difference between the sensu Insecta term and the generic term.					True			biological_process											owl:Class	
GO:0016565	biolink:NamedThing	obsolete general transcriptional repressor activity	OBSOLETE. Any activity that stops or downregulates transcription of genes globally, and is not specific to a particular gene or gene set.	tmpzr1t_l9r_go_relaxed.owl	general transcriptional repressor activity					This term was obsoleted because "general/nonspecific/basal" transcription vs "specific" transcription were determined not to be separable, distinct process. Thus, terms trying to distinguish "general/nonspecific/basal" transcription from "specific" transcription were removed from both the Molecular Function and the Biological Process ontologies. In addition, this Molecular Function term was defined only in terms of the process it acts in and it does NOT convey any information about the molecular nature of the function or whether the function is based on binding DNA, on interacting with other proteins, or some other mechanism. To transfer all annotations without review, the BP term indicated is considered to be equivalent and thus the only appropriate destination for all annotations. To reannotate to a MF term, you will probably need to revisit the original literature or other primary data because this "MF" term was not defined in terms of mechanism of action and there are multiple possibilities in the revised MF structure. In reannotation, please also consider descendent terms of the suggested MF terms as a more specific term may be more appropriate than the MF terms indicated. Please be aware that you may wish to request a new term if the mechanism of action of your repressor is not yet represented or if you are annotating for an RNAP different than one for which there is a specific suggested term. Also note that if there is no information about how the gene product acts, it may be appropriate to annotate to the root term for molecular_function.	GO:0045892|GO:0001217|GO:0001227				True			molecular_function											owl:Class	
GO:1904922	biolink:NamedThing	obsolete positive regulation of MAPK cascade involved in axon regeneration	OBSOLETE. Any process that activates or increases the frequency, rate or extent of MAPK cascade involved in axon regeneration.	tmpzr1t_l9r_go_relaxed.owl	activation of MAPKKK cascade during sporulation involved in axon regeneration|upregulation of mitogen-activated protein kinase cascade involved in axon regeneration|positive regulation of ERK/MAPK cascade involved in axon regeneration|positive regulation of mitogen-activated protein kinase cascade involved in axon regeneration|upregulation of MAPK signal transduction involved in axon regeneration|up-regulation of ERK/MAPK cascade involved in axon regeneration|up-regulation of MAP kinase cascade involved in axon regeneration|up-regulation of mitogen-activated protein kinase cascade involved in axon regeneration|positive regulation of MAPK signaling involved in axon regeneration|positive regulation of MAPK signalling involved in axon regeneration|upregulation of MAPKKK cascade involved in axon regeneration|activation of MAP kinase kinase kinase cascade involved in axon regeneration|positive regulation of MAPK signal transduction involved in axon regeneration|upregulation of MAPKKK cascade during sporulation involved in axon regeneration|activation of MAP kinase cascade involved in axon regeneration|up regulation of MAPKKK cascade involved in axon regeneration|activation of MAPKKK cascade involved in axon regeneration|positive regulation of MAP kinase cascade involved in axon regeneration|positive regulation of MAP kinase kinase kinase cascade involved in axon regeneration|up regulation of ERK/MAPK cascade involved in axon regeneration|activation of MAPK signal transduction involved in axon regeneration|up-regulation of MAPK signaling involved in axon regeneration|activation of mitogen-activated protein kinase cascade involved in axon regeneration|activation of MAPK signalling involved in axon regeneration|activation of MAPK signaling involved in axon regeneration|up regulation of MAPK cascade involved in axon regeneration|upregulation of MAPK signalling involved in axon regeneration|upregulation of ERK/MAPK cascade involved in axon regeneration|up regulation of MAPK signalling involved in axon regeneration|up-regulation of MAPKKK cascade involved in axon regeneration|up-regulation of MAPK signal transduction involved in axon regeneration|upregulation of MAP kinase cascade involved in axon regeneration|up regulation of MAPK signal transduction involved in axon regeneration|up-regulation of MAP kinase kinase kinase cascade involved in axon regeneration|up regulation of mitogen-activated protein kinase cascade involved in axon regeneration|up regulation of MAP kinase cascade involved in axon regeneration|upregulation of MAP kinase kinase kinase cascade involved in axon regeneration|upregulation of MAPK cascade involved in axon regeneration|up regulation of MAP kinase kinase kinase cascade involved in axon regeneration|upregulation of MAPK signaling involved in axon regeneration|activation of MAPK cascade involved in axon regeneration|up-regulation of MAPKKK cascade during sporulation involved in axon regeneration|up-regulation of MAPK cascade involved in axon regeneration|positive regulation of MAPKKK cascade involved in axon regeneration|up regulation of MAPKKK cascade during sporulation involved in axon regeneration|positive regulation of MAPKKK cascade during sporulation involved in axon regeneration|up regulation of MAPK signaling involved in axon regeneration|activation of ERK/MAPK cascade involved in axon regeneration|up-regulation of MAPK signalling involved in axon regeneration	https://github.com/geneontology/go-ontology/issues/14323				This term was obsoleted because it represents a GO-CAM model.		kmv	2016-01-25T17:03:49Z		True			biological_process											owl:Class	
GO:0045767	biolink:NamedThing	obsolete regulation of anti-apoptosis	OBSOLETE. Any process that modulates the frequency, rate or extent of anti-apoptosis.	tmpzr1t_l9r_go_relaxed.owl	regulation of anti-apoptosis					This term was made obsolete because it was ill-defined.					True			biological_process											owl:Class	
GO:0009483	biolink:NamedThing	obsolete caa3-type cytochrome c oxidase	OBSOLETE. Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: 4 ferrocytochrome c + O2 = 4 ferricytochrome c + 2 H2O.	tmpzr1t_l9r_go_relaxed.owl	caa3-type cytochrome c oxidase			GO:0004129		This term was made obsolete because it describes a class of gene products rather than a molecular function.					True			molecular_function											owl:Class	
GO:0016506	biolink:NamedThing	obsolete apoptosis activator activity	OBSOLETE. The function held by products which directly activate any step in the process of apoptosis.	tmpzr1t_l9r_go_relaxed.owl	apoptosis activator activity			GO:0006915		This term was made obsolete because it represents involvement in a biological process.					True			molecular_function											owl:Class	
GO:0051803	biolink:NamedThing	obsolete negative regulation of cytolysis in other organism involved in symbiotic interaction	OBSOLETE. Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of cytolysis by that organism of cells in a second organism, where the two organisms are in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of cytolysis of cells in other organism during symbiotic interaction|down-regulation of cytolysis of cells in other organism during symbiotic interaction|negative regulation of cytolysis of cells in other organism involved in symbiotic interaction|inhibition of cytolysis of cells in other organism during symbiotic interaction|down regulation of cytolysis of cells in other organism during symbiotic interaction|downregulation of cytolysis of cells in other organism during symbiotic interaction					This term was obsoleted because it represents an unnecessary grouping class.					True			biological_process											owl:Class	
GO:0045888	biolink:NamedThing	obsolete regulation of transcription of homeotic gene (Polycomb group)	OBSOLETE. Any process that modulates the frequency, rate or extent of transcription of homeotic genes of the Polycomb group.	tmpzr1t_l9r_go_relaxed.owl	regulation of transcription of homeotic gene (Polycomb group)					This term was made obsolete because it relates to a specific gene family rather than a process.	GO:0006357				True			biological_process											owl:Class	
GO:0008450	biolink:NamedThing	obsolete O-sialoglycoprotein endopeptidase activity	OBSOLETE. Catalysis of the hydrolysis of O-sialoglycoproteins; cleaves the -Arg31-Asp32- bond in glycophorin A. Does not cleave unglycosylated proteins, desialylated glycoproteins or glycoproteins that are only N-glycosylated.	tmpzr1t_l9r_go_relaxed.owl	sialoglycoproteinase activity|glycophorin A proteinase activity|sialoglycoprotease activity|glycoprotease activity|O-sialoglycoprotein endopeptidase activity|glycoproteinase activity			GO:0004222		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0008956	biolink:NamedThing	obsolete peptidyl-dipeptidase Dcp activity	OBSOLETE. Catalysis of the hydrolysis of unblocked, C-terminal dipeptides from oligopeptides, with broad specificity. Does not hydrolyze bonds in which P1' is Pro, or both P1 and P1' are Gly.	tmpzr1t_l9r_go_relaxed.owl	dipeptidyl carboxypeptidase (Dcp)|peptidyl-dipeptidase Dcp activity|dipeptidyl carboxypeptidase activity				EC:3.4.15.5|MetaCyc:3.4.15.5-RXN	This term was made obsolete because it represents a gene product.	GO:0008241|GO:0008235				True			molecular_function											owl:Class	
GO:0001040	biolink:NamedThing	obsolete RNA polymerase III hybrid type promoter TFIIIB-type transcription factor activity	OBSOLETE. Binding to an RNA polymerase III (Pol III) complex, typically composed of seventeen subunits, and with another protein, macromolecule, or complex, permitting those molecules to function in a coordinated way. Once recruited to an RNA polymerase III hybrid type promoter, binds to DNA, recruits RNA polymerase III and facilitates the transition from the closed to the open complex.	tmpzr1t_l9r_go_relaxed.owl						The reason for obsoletion is that there is a single TFIIIB activity; this is not dependent on the promoter.		krc	2010-08-23T06:28:23Z		True			molecular_function											owl:Class	
GO:0046808	biolink:NamedThing	obsolete assemblon	OBSOLETE. Antigenically dense structures located at the periphery of nuclei, close to but not abutting nuclear membranes. Assemblons contain the proteins for immature-capsid assembly; they are located at the periphery of a diffuse structure composed of proteins involved in DNA synthesis, which overlaps only minimally with the assemblons. More than one site can be present simultaneously.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/20746				This term was obsoleted because it does not correspond to a real cellular component, but to a site of immunoreactivity.					True			cellular_component											owl:Class	
GO:0052568	biolink:NamedThing	obsolete response to symbiont phytoalexin production	OBSOLETE. A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of phytoalexins produced as part of the defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	response to symbiont phytoalexin production					This term was made obsolete because it does not represent a real biological process.					True			biological_process											owl:Class	
GO:0019847	biolink:NamedThing	obsolete neurotoxin activity	OBSOLETE. Acts to inhibit neural function in another living organism.	tmpzr1t_l9r_go_relaxed.owl	neurotoxin activity					This term was made obsolete because it represents a class of gene products.	GO:0090729				True			molecular_function											owl:Class	
GO:0030816	biolink:NamedThing	obsolete positive regulation of cAMP metabolic process	OBSOLETE. Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate).	tmpzr1t_l9r_go_relaxed.owl	positive regulation of adenosine 3',5'-cyclophosphate metabolic process|positive regulation of adenosine 3',5'-cyclophosphate metabolism|activation of cAMP metabolic process|positive regulation of cAMP metabolism|upregulation of cAMP metabolic process|positive regulation of 3',5'-cAMP metabolism|positive regulation of 3',5'-cAMP metabolic process|positive regulation of 3',5' cAMP metabolic process|positive regulation of cyclic AMP metabolic process|up-regulation of cAMP metabolic process|positive regulation of 3',5' cAMP metabolism|up regulation of cAMP metabolic process|stimulation of cAMP metabolic process|positive regulation of cyclic AMP metabolism					The reason for obsoletion is that this term represents the regulation of a signaling pathway, not regulation of metabolism.					True			biological_process											owl:Class	
GO:0001526	biolink:NamedThing	obsolete proteoglycan sulfate transfer	OBSOLETE. Transfer of sulfate to a proteoglycan (a glycoprotein whose carbohydrate units are glycosaminoglycans) using 3'-phosphoadenyl sulfate.	tmpzr1t_l9r_go_relaxed.owl	proteoglycan sulfate transfer|proteoglycan sulphate transfer					This term was made obsolete because it represents a group of molecular functions.	GO:0006790|GO:0050698|GO:0006029				True			biological_process											owl:Class	
GO:0019837	biolink:NamedThing	obsolete herbicide susceptibility/resistance	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	herbicide susceptibility/resistance			GO:0009635		This term was made obsolete because 'susceptibility/resistance' implies a phenotype rather than a biological process.					True			biological_process											owl:Class	
GO:0003812	biolink:NamedThing	obsolete alternative-complement-pathway C3/C5 convertase activity	OBSOLETE. Catalysis of the cleavage of Arg-Ser bond in complement component C3 alpha-chain to yield C3a and C3b, and Arg bond in complement component C5 alpha-chain to yield C5a and C5b.	tmpzr1t_l9r_go_relaxed.owl	heat-labile factor|C3 proactivator|alternative complement pathway C3(C5) convertase activity|cobra venom factor-dependent C3 convertase|alternative-complement-pathway C3/C5 convertase activity|C3 convertase activity|C3b,Bb,CVF,Bb,C5 convertase activity|complement component C3/C5 convertase (alternative) activity|(CVF)-dependent glycine-rich-beta-glucoprotein|(C3b)n,Bb|C5 convertase activity|glycine-rich beta-glycoprotein|properdin factor B activity|complement factor B activity|complement C 3(C 5) convertase (amplification)|CVF,Bb|proenzyme factor B			GO:0004252		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0047859	biolink:NamedThing	obsolete dihydroxyphenylalanine ammonia-lyase activity	OBSOLETE. Catalysis of the reaction: 3,4-dihydroxy-L-phenylalanine = trans-caffeate + NH3.	tmpzr1t_l9r_go_relaxed.owl	dihydroxyphenylalanine ammonia-lyase activity|3,4-dihydroxy-L-phenylalanine ammonia-lyase activity|beta-(3,4-dihydroxyphenyl)-L-alanine (DOPA) ammonia-lyase activity|3,4-dihydroxy-L-phenylalanine ammonia-lyase (trans-caffeate-forming)				EC:4.3.1.11	This term was made obsolete because the corresponding EC reaction (EC:4.3.1.11) has been deleted from the EC.					True			molecular_function											owl:Class	
GO:0008451	biolink:NamedThing	obsolete X-Pro aminopeptidase activity	OBSOLETE. Catalysis of the release of an N-terminal amino acid, including proline, that is linked with proline, even from a dipeptide or tripeptide.	tmpzr1t_l9r_go_relaxed.owl	Xaa-Pro aminopeptidase activity|X-Pro aminopeptidase activity|aminopeptidase P|proline aminopeptidase|aminoacylproline aminopeptidase activity			GO:0004177		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:1990848	biolink:NamedThing	obsolete Positive regulation of removal of reactive oxygen species	OBSOLETE. Any process that increases the frequency, rate or extent of removal of reactive oxygen species in a cell.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted at the TermGenie Gatekeeper stage.		al	2015-09-09T11:59:57Z		True			biological_process											owl:Class	
GO:0004248	biolink:NamedThing	obsolete stromelysin 1 activity	OBSOLETE. Catalysis of the preferential cleavage where P1', P2' and P3' are hydrophobic residues.	tmpzr1t_l9r_go_relaxed.owl	MMP-3|procollagenase activator|collagen-activating protein|proteoglycanase activity|matrix metalloproteinase 3 activity|collagenase activating protein|stromelysin 1 activity|neutral proteoglycanase activity|stromelysin|transin activity			GO:0004222		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:1901206	biolink:NamedThing	obsolete positive regulation of adrenergic receptor signaling pathway involved in heart process	OBSOLETE. Any process that activates or increases the frequency, rate or extent of a cardiac adrenergic receptor signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of beta-adrenergic receptor signalling pathway involved in heart process|activation of beta-adrenergic receptor signalling pathway involved in heart process|up regulation of adrenergic receptor signaling pathway involved in heart process|upregulation of beta-adrenergic receptor signalling pathway involved in heart process|upregulation of adrenergic receptor signalling pathway involved in heart process|up-regulation of adrenergic receptor signaling pathway involved in heart process|upregulation of adrenergic receptor signaling pathway involved in heart process|activation of adrenergic receptor signalling pathway involved in heart process|up-regulation of adrenergic receptor signalling pathway involved in heart process|activation of adrenergic receptor signaling pathway involved in heart process|up regulation of beta-adrenergic receptor signalling pathway involved in heart process|up-regulation of beta-adrenergic receptor signalling pathway involved in heart process|up regulation of adrenergic receptor signalling pathway involved in heart process|positive regulation of adrenergic receptor signalling pathway involved in heart process	https://github.com/geneontology/go-ontology/issues/14733				This term was obsoleted because it is not precise enough. We must specify if the ACA-activating or ACA inhibiting pathway is the target of the regulation.		hjd	2012-07-30T18:33:22Z		True			biological_process											owl:Class	
GO:0005648	biolink:NamedThing	obsolete importin, beta-subunit	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	importin, beta-subunit|karyopherin-beta1					This term was made obsolete because it represents a single gene product and not a complex.	GO:0005737|GO:0017056|GO:0005634|GO:0005643				True			cellular_component											owl:Class	
GO:0005711	biolink:NamedThing	obsolete meiotic chromosome	OBSOLETE. A chromosome involved in the process of meiosis.	tmpzr1t_l9r_go_relaxed.owl	meiotic chromosome					This term was made obsolete because it is based on a process.	GO:0000794				True			cellular_component											owl:Class	
GO:0019000	biolink:NamedThing	obsolete endonuclease G activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	endonuclease G activity					This term was made obsolete because it represents a gene product.	GO:0004521|GO:0004520				True			molecular_function											owl:Class	
GO:0008492	biolink:NamedThing	obsolete cAMP generating peptide activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	cyclic AMP generating peptide activity|cAMP generating peptide activity					This term was made obsolete because it describes a gene product.	GO:0005179|GO:0004016|GO:0046058				True			molecular_function											owl:Class	
GO:1903483	biolink:NamedThing	obsolete regulation of maintenance of mitotic actomyosin contractile ring localization	OBSOLETE. Any process that modulates the frequency, rate or extent of maintenance of mitotic actomyosin contractile ring localization.	tmpzr1t_l9r_go_relaxed.owl	regulation of maintenance of contractile ring localization involved in cytokinesis during cell cycle involved in mitotic cell cycle|regulation of maintenance of contractile ring localisation involved in cell cycle cytokinesis involved in mitotic cell cycle|regulation of cytokinetic ring anchoring involved in mitotic cell cycle|regulation of maintenance of contractile ring localization involved in cell cycle cytokinesis involved in mitotic cell cycle					The reason for obsoletion is that this term represents a GO-CAM model.		vw	2014-09-23T16:12:19Z		True			biological_process											owl:Class	
GO:1903485	biolink:NamedThing	obsolete positive regulation of maintenance of mitotic actomyosin contractile ring localization	OBSOLETE. Any process that activates or increases the frequency, rate or extent of maintenance of mitotic actomyosin contractile ring localization.	tmpzr1t_l9r_go_relaxed.owl	up regulation of cytokinetic ring anchoring involved in mitotic cell cycle|activation of maintenance of contractile ring localisation involved in cell cycle cytokinesis involved in mitotic cell cycle|up regulation of maintenance of contractile ring localisation involved in cell cycle cytokinesis involved in mitotic cell cycle|activation of cytokinetic ring anchoring involved in mitotic cell cycle|positive regulation of maintenance of contractile ring localization involved in cell cycle cytokinesis involved in mitotic cell cycle|positive regulation of cytokinetic ring anchoring involved in mitotic cell cycle|up regulation of maintenance of mitotic actomyosin contractile ring localization|upregulation of cytokinetic ring anchoring involved in mitotic cell cycle|up regulation of maintenance of contractile ring localization involved in cytokinesis during cell cycle involved in mitotic cell cycle|activation of maintenance of contractile ring localization involved in cytokinesis during cell cycle involved in mitotic cell cycle|up-regulation of maintenance of contractile ring localization involved in cell cycle cytokinesis involved in mitotic cell cycle|up-regulation of maintenance of mitotic actomyosin contractile ring localization|up-regulation of maintenance of contractile ring localisation involved in cell cycle cytokinesis involved in mitotic cell cycle|upregulation of maintenance of contractile ring localization involved in cell cycle cytokinesis involved in mitotic cell cycle|up regulation of maintenance of contractile ring localization involved in cell cycle cytokinesis involved in mitotic cell cycle|up-regulation of maintenance of contractile ring localization involved in cytokinesis during cell cycle involved in mitotic cell cycle|up-regulation of cytokinetic ring anchoring involved in mitotic cell cycle|upregulation of maintenance of contractile ring localisation involved in cell cycle cytokinesis involved in mitotic cell cycle|activation of maintenance of mitotic actomyosin contractile ring localization|activation of maintenance of contractile ring localization involved in cell cycle cytokinesis involved in mitotic cell cycle|positive regulation of maintenance of contractile ring localisation involved in cell cycle cytokinesis involved in mitotic cell cycle|upregulation of maintenance of mitotic actomyosin contractile ring localization|positive regulation of maintenance of contractile ring localization involved in cytokinesis during cell cycle involved in mitotic cell cycle|upregulation of maintenance of contractile ring localization involved in cytokinesis during cell cycle involved in mitotic cell cycle					The reason for obsoletion is that this term represents a GO-CAM model.		vw	2014-09-23T16:12:37Z		True			biological_process											owl:Class	
GO:0071536	biolink:NamedThing	obsolete RING-like zinc finger domain-mediated complex assembly	OBSOLETE. A process of protein complex assembly in which the arrangement and bonding together of the set of components that form the protein complex is mediated by a RING-like zinc finger domain interaction.	tmpzr1t_l9r_go_relaxed.owl	RING-like domain-mediated complex assembly					This term was obsoleted because it represented a molecular function (binding), not a biological process.  The term represented a domain involved in protein-protein interactions, but no necessarily the process of assembling a complex.		mah	2010-01-08T03:19:47Z		True			biological_process											owl:Class	
GO:2000460	biolink:NamedThing	obsolete regulation of eukaryotic cell surface binding	OBSOLETE. Any process that modulates the frequency, rate or extent of eukaryotic cell surface binding.	tmpzr1t_l9r_go_relaxed.owl	regulation of eukaryotic cell surface binding					This term was made obsolete because the cell surface binding terms are ambiguous grouping terms and were causing confusion.	GO:0031347|GO:1900120	yaf	2011-03-04T11:59:52Z		True			biological_process											owl:Class	
GO:1990449	biolink:NamedThing	obsolete amylin receptor	OBSOLETE. A G protein-coupled signalling receptor complex consisting of the calcitonin receptor and a receptor activity-modifying protein (RAMP). Amylin is produced in beta-islet cells of the pancreas. It is implicated in selective inhibition of insulin-stimulated glucose utilization and glycogen deposition in muscle, gastric emptying, gastric acid secretion, postprandial glucagon secretion and food intake and aids weight loss.	tmpzr1t_l9r_go_relaxed.owl	AMY2 receptor|AMY1 receptor|CALCR-RAMP1 receptor|CALCR-RAMP2 receptor|CALCR-RAMP3 receptor|AMY3 receptor|amylin receptor					An example of this is CALCR in human (P30988) in PMID:10871269.		bhm	2014-08-06T10:21:37Z		True			cellular_component											owl:Class	
GO:2000581	biolink:NamedThing	obsolete negative regulation of microtubule motor activity, plus-end-directed	OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of ATP-dependent microtubule motor activity, plus-end-directed.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of ATP-dependent microtubule motor activity, plus-end-directed|negative regulation of plus-end-directed kinesin ATPase activity|negative regulation of kinesin activity|negative regulation of plus-end-directed microtubule motor activity|negative regulation of kinesin ATP phosphohydrolase (plus-end-directed)	https://github.com/geneontology/go-ontology/issues/21626				This term was obsoleted because it represents a molecular function.	GO:0140661	bf	2011-04-05T08:39:49Z		True			biological_process											owl:Class	
GO:1990894	biolink:NamedThing	obsolete positive regulation of induction of conjugation with cellular fusion by regulation of transcription from RNA polymerase II promoter	OBSOLETE. A regulation of transcription from RNA polymerase II promoter that results in positive regulation of induction of conjugation with cellular fusion.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted during the TG review process.  It should have been created using a template.		al	2015-11-04T20:25:21Z		True			biological_process											owl:Class	
GO:1902862	biolink:NamedThing	obsolete glycerol catabolic process to glycerone phosphate	OBSOLETE. The chemical reactions and pathways resulting in the breakdown of glycerol to glycerone phosphate.	tmpzr1t_l9r_go_relaxed.owl	glycerol breakdown to glycerone phosphate|glycerol degradation to glycerone phosphate|glycerol catabolism to glycerone phosphate|glycerol catabolic process to glycerone phosphate					This term was obsoleted at the TermGenie Gatekeeper stage.		dph	2014-04-03T14:42:01Z		True			biological_process											owl:Class	
GO:0060144	biolink:NamedThing	obsolete host cellular process involved in virus induced gene silencing	OBSOLETE. A cellular process occurring in the host cell that contributes to the process of posttranscriptional gene inactivation ('silencing') both of viral gene(s), and host gene(s) homologous to the viral genes.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/19958				The reason for obsoletion is there there is no evidence that this process exists.					True			biological_process											owl:Class	
GO:0072333	biolink:NamedThing	obsolete anoikis by p53 class mediator	OBSOLETE. A cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, that results in the induction of anoikis.	tmpzr1t_l9r_go_relaxed.owl	signal transduction by p53 class mediator resulting in induction of anoikis|anoikis by signal transduction by p53 class mediator|anoikis by p53 class mediator					This term was made obsolete because it is misleading, since anoikis occurs following detachment of cells from each other and/or from the culture surface; it is not p53 that induces such separation.		mah	2010-11-03T01:52:56Z		True			biological_process											owl:Class	
GO:0051817	biolink:NamedThing	obsolete modulation of process of other organism involved in symbiotic interaction	OBSOLETE. The process in which an organism effects a change in the structure or processes of a second organism, where the two organisms are in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	regulation of morphology of other organism during symbiotic interaction|modulation of morphology or physiology of other organism during symbiotic interaction|modification of morphology or physiology of other organism during symbiotic interaction|modulation of biological process of other organism involved in symbiotic interaction|modification of morphology or physiology of other organism involved in symbiotic interaction|regulation of physiological process in other organism during symbiotic interaction|regulation of morphology or physiology of other organism during symbiotic interaction|regulation of physiology of other organism during symbiotic interaction	https://github.com/geneontology/go-ontology/issues/18605				This term was obsoleted because it represents an unnecessary grouping class.					True			biological_process											owl:Class	
GO:0052120	biolink:NamedThing	obsolete positive aerotaxis in host environment	OBSOLETE. The directed movement of a motile cell or organism towards a higher concentration of environmental oxygen on, within or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	positive aerotaxis in response to host environment	https://github.com/geneontology/go-ontology/issues/18819				This term was obsoleted because it represents both a process and a location.					True			biological_process											owl:Class	
GO:0052584	biolink:NamedThing	obsolete oxidoreductase activity, acting on halogen in donors, with NAD or NADP as acceptor	OBSOLETE. Catalysis of an oxidation-reduction in which a halogen in the donor substance acts as a hydrogen or electron donor and reduces NAD or NADP.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/20613			EC:1.22.1.-	This term was obsoleted because EC obsoleted it, and there was no other evidence that this function exists.		ai	2010-08-13T10:17:56Z		True			molecular_function											owl:Class	
GO:0038067	biolink:NamedThing	obsolete MAP kinase activity involved in cell wall organization or biogenesis	OBSOLETE. Catalysis of the reaction: protein + ATP = protein phosphate + ADP by a mitogen-activated protein kinase, as part of a MAPK signaling cascade that contributes to cell wall organization or biogenesis.	tmpzr1t_l9r_go_relaxed.owl	MAP kinase activity involved in cell wall biogenesis|MAP kinase activity involved in cell wall integrity|MAPK activity involved in cell wall biogenesis					This term has been obsoleted because it represents a GO-CAM model rather than a single GO term.		bf	2012-01-25T03:29:04Z		True			molecular_function											owl:Class	
GO:1990801	biolink:NamedThing	obsolete protein phosphorylation involved in mitotic spindle assembly	OBSOLETE. Any protein phosphorylation that is involved in mitotic spindle assembly.	tmpzr1t_l9r_go_relaxed.owl	protein phosphorylation involved in spindle assembly involved in mitosis|protein amino acid phosphorylation involved in mitotic spindle assembly|protein amino acid phosphorylation involved in spindle assembly involved in mitosis	https://github.com/geneontology/go-ontology/issues/14137				This term has been obsoleted because it represents a GO-CAM model.		rb	2015-07-16T18:36:05Z		True			biological_process											owl:Class	
GO:0075167	biolink:NamedThing	obsolete negative regulation of G-protein gamma subunit-mediated signal transduction in response to host	OBSOLETE. Any process in which the symbiont organism stops, prevents, or reduces the frequency, rate or extent of its symbiont G-protein gamma subunit-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of symbiont G-protein gamma subunit-mediated signal transduction in response to host					This term was obsoleted because there is no evidence that this process exists.					True			biological_process											owl:Class	
GO:0035961	biolink:NamedThing	obsolete positive regulation of ergosterol biosynthetic process by positive regulation of transcription from RNA polymerase II promoter	OBSOLETE. Any process that activates or increases the frequency, rate or extent of ergosterol biosynthesis by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of ergosterol biosynthesis by up-regulation of transcription from RNA polymerase II promoter|positive regulation of ergosterol biosynthetic process by stimulation of transcription from RNA polymerase II promoter|positive regulation of ergosterol anabolism by up regulation of transcription from RNA polymerase II promoter|positive regulation of ergosterol biosynthesis by positive regulation of transcription from Pol II promoter|positive regulation of ergosterol synthesis by positive regulation of transcription from Pol II promoter|positive regulation of ergosterol anabolism by positive regulation of transcription from RNA polymerase II promoter|positive regulation of ergosterol synthesis by up-regulation of transcription from RNA polymerase II promoter|positive regulation of ergosterol biosynthetic process by up regulation of transcription from RNA polymerase II promoter|positive regulation of ergosterol formation by upregulation of transcription from RNA polymerase II promoter|positive regulation of ergosterol biosynthetic process by activation of transcription from RNA polymerase II promoter|positive regulation of ergosterol synthesis by upregulation of transcription from RNA polymerase II promoter|positive regulation of ergosterol biosynthesis by up regulation of transcription from RNA polymerase II promoter|positive regulation of ergosterol anabolism by positive regulation of transcription from Pol II promoter|positive regulation of ergosterol biosynthesis by positive regulation of transcription from RNA polymerase II promoter|positive regulation of ergosterol synthesis by up regulation of transcription from RNA polymerase II promoter|positive regulation of ergosterol synthesis by positive regulation of transcription from RNA polymerase II promoter|positive regulation of ergosterol formation by up regulation of transcription from RNA polymerase II promoter|positive regulation of ergosterol anabolism by upregulation of transcription from RNA polymerase II promoter|positive regulation of ergosterol biosynthetic process by up-regulation of transcription from RNA polymerase II promoter|positive regulation of ergosterol anabolism by up-regulation of transcription from RNA polymerase II promoter|positive regulation of ergosterol biosynthetic process by positive regulation of transcription from Pol II promoter|positive regulation of ergosterol formation by positive regulation of transcription from RNA polymerase II promoter|positive regulation of ergosterol formation by positive regulation of transcription from Pol II promoter|positive regulation of ergosterol biosynthetic process by upregulation of transcription from RNA polymerase II promoter|positive regulation of ergosterol formation by up-regulation of transcription from RNA polymerase II promoter|positive regulation of ergosterol biosynthesis by upregulation of transcription from RNA polymerase II promoter					This term was obsoleted because it represents a GO-CAM model.		bf			True			biological_process											owl:Class	
GO:0000094	biolink:NamedThing	obsolete septin assembly and septum formation	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	septin assembly and septum formation					This term was made obsolete because it was not defined and the string name implied two separate processes.	GO:0000917|GO:0000921|GO:0000918				True			biological_process											owl:Class	
GO:0035417	biolink:NamedThing	obsolete negative regulation of mitotic prometaphase	OBSOLETE. Any process that stops, prevents or reduces the rate or extent of mitotic prometaphase, the stage following prophase in mitosis (in higher eukaryotes) during which the nuclear envelope is disrupted and breaks into membrane vesicles, and the spindle microtubules enter the nuclear region.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of mitotic prometaphase					This term was made obsolete as part of the cell cycle overhaul. This is because it was decided that cell cycle phases are intervals and so cannot be regulated, rather it is the transitions between the phases that are regulated.		bf	2010-03-29T10:53:42Z		True			biological_process											owl:Class	
GO:1990492	biolink:NamedThing	obsolete mitotic cell cycle checkpoint inhibiting CAR assembly	OBSOLETE. A Mad2-dependent mitotic cell cycle checkpoint which delays cytokinetic actinomycin ring assembly if there is a delay in early M-phase.	tmpzr1t_l9r_go_relaxed.owl	Mad2-dependent mitotic cell cycle checkpoint|mitotic cell cycle checkpoint inhibiting cytokinetic actomyosin ring assembly					This term was obsoleted because it does not represent a specific process.		vw	2014-09-23T12:43:22Z		True			biological_process											owl:Class	
GO:1990912	biolink:NamedThing	obsolete response to microwave radiation	OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a microwave radiation stimulus.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted at the TermGenie Gatekeeper stage.		sl	2015-12-07T21:25:08Z		True			biological_process											owl:Class	
GO:0016912	biolink:NamedThing	obsolete SAP kinase 5 activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	SAP kinase 5 activity|SAPK5					This term was made obsolete because there are no known gene products that would be described as 'SAP kinase 5', and the term name implies that it refers to a gene product.	GO:0004674|GO:0007254				True			molecular_function											owl:Class	
GO:0100066	biolink:NamedThing	obsolete negative regulation of induction of conjugation with cellular fusion by transcription from RNA polymerase II promoter	OBSOLETE. Any transcription from RNA polymerase II promoter process that negatively regulates induction of conjugation with cellular fusion.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it represents a GO-CAM model.		cjm	2015-04-02T04:13:19Z		True			biological_process											owl:Class	
GO:0015442	biolink:NamedThing	obsolete hydrogen-/sodium-translocating ATPase activity	OBSOLETE. Catalysis of the reaction: ATP + H2O + (Na+ or H+)(in) = ADP + phosphate + (Na+ or H+)(out).	tmpzr1t_l9r_go_relaxed.owl	hydrogen-/sodium-translocating ATPase activity|proton-/sodium-translocating ATPase activity					This term was made obsolete because it is a redundant grouping term based on a TC-DB classification.	GO:0008554|GO:0008553				True			molecular_function											owl:Class	
GO:0000108	biolink:NamedThing	obsolete repairosome	OBSOLETE. A stable complex of proteins that carry out the DNA damage recognition and incision reactions characteristic of nucleotide excision repair (NER), such as DNA damage recognition, DNA helix unwinding, and endonucleolytic cleavage at sites flanking damaged DNA; includes TFIIH subunits and additional polypeptides; may form in the absence of DNA damage.	tmpzr1t_l9r_go_relaxed.owl	repairosome			GO:0000109		This term was made obsolete because 'repairosome' has fallen out of use in the literature, and the large complex described in the definition has not been confirmed to exist. The term has also confused annotators.					True			cellular_component											owl:Class	
GO:0005533	biolink:NamedThing	obsolete N-acetylgalactosamine lectin	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	N-acetylgalactosamine lectin					This term was made obsolete because it refers to a class of gene products.	GO:0046871|GO:0007157				True			molecular_function											owl:Class	
GO:0071531	biolink:NamedThing	obsolete Rel homology domain-mediated complex assembly	OBSOLETE. A process of protein complex assembly in which the arrangement and bonding together of the set of components that form the protein complex is mediated by a Rel homology domain (RHD) interaction.	tmpzr1t_l9r_go_relaxed.owl	RHD domain-mediated complex assembly					This term was obsoleted because it represented a molecular function (binding), not a biological process.  The term represented a domain involved in protein-protein interactions, but no necessarily the process of assembling a complex.		mah	2010-01-08T02:16:39Z		True			biological_process											owl:Class	
GO:0090146	biolink:NamedThing	obsolete establishment of mitochondrion localization involved in mitochondrial fission	OBSOLETE. The directed movement of mitochondria to the correct region of the cell that contributes to the process of mitochondrial fission.	tmpzr1t_l9r_go_relaxed.owl	mitochondrial localization involved in mitochondrial fission|establishment of mitochondrion localisation involved in mitochondrial fission	https://github.com/geneontology/go-ontology/issues/18417				This term was obsoleted because it represented a phenotype.	GO:0000266|GO:0000002	tb	2009-12-08T02:53:15Z		True			biological_process											owl:Class	
GO:0031939	biolink:NamedThing	obsolete negative regulation of chromatin silencing at telomere	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of chromatin silencing at telomeres.	tmpzr1t_l9r_go_relaxed.owl	down regulation of chromatin silencing at telomere|down-regulation of chromatin silencing at telomere|negative regulation of heterochromatic silencing at telomere|inhibition of chromatin silencing at telomere|downregulation of chromatin silencing at telomere	https://github.com/geneontology/go-ontology/issues/22027				This term was obsoleted because there is no evidence that chromatin silencing /heterochromatin assembly are directly regulated.					True			biological_process											owl:Class	
GO:0046609	biolink:NamedThing	obsolete voltage-gated sulfate antiporter activity	OBSOLETE. Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sulfate(out) + solute(in) = solute(in) + sulfate(out), by a channel in a cell membrane whose opening is governed by the membrane potential.	tmpzr1t_l9r_go_relaxed.owl	voltage-dependent sulfate antiporter activity|voltage gated sulfate antiporter activity|voltage-sensitive sulphate antiporter activity|prestin|voltage-sensitive sulfate antiporter activity					This term was obsoleted because there is no evidence that this function exists.					True			molecular_function											owl:Class	
GO:0052116	biolink:NamedThing	obsolete chemotaxis in host environment	OBSOLETE. The directed movement of a motile cell or organism in response to a specific chemical concentration gradient on, within or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	chemotaxis in response to host environment	https://github.com/geneontology/go-ontology/issues/18819				This term was obsoleted because it represents both a process and a location.					True			biological_process											owl:Class	
GO:0075301	biolink:NamedThing	obsolete cell differentiation involved in spore germination	OBSOLETE. The process in which a relatively unspecialized cell acquires specialized features of a specific cell type occurring during spore germination, the physiological and developmental changes that occur in a spore following release from dormancy up to the earliest signs of growth.	tmpzr1t_l9r_go_relaxed.owl						This term was made obsolete because it describes a process that doesn't exist.					True			biological_process											owl:Class	
GO:0003683	biolink:NamedThing	obsolete lamin/chromatin binding	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	lamin/chromatin binding					This term was made obsolete because it represents two functions.	GO:0005521|GO:0003682				True			molecular_function											owl:Class	
GO:0010680	biolink:NamedThing	obsolete cinnamic acid biosynthetic process involved in coumarin metabolism	OBSOLETE. The chemical reactions and pathways resulting in the formation of cinnamic acid, 3-phenyl-2-propenoic acid, which is then utilized in the metabolism of coumarin.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/18200				This term was obsoleted because it does not represent a specific pathway.					True			biological_process											owl:Class	
GO:0045212	biolink:NamedThing	obsolete neurotransmitter receptor biosynthetic process	OBSOLETE. The chemical reactions and pathways resulting in the formation of neurotransmitter receptors.	tmpzr1t_l9r_go_relaxed.owl	neurotransmitter receptor biosynthesis|neurotransmitter receptor anabolism|neurotransmitter receptor formation|neurotransmitter receptor synthesis	https://github.com/geneontology/go-ontology/issues/19900				The reason for obsoletion is that those represent specific gene products, and genes annotated to those terms should be annotated to 'regulation of gene expression' or 'regulation of transcription' or some signaling term.					True			biological_process											owl:Class	
GO:0005803	biolink:NamedThing	obsolete secretory vesicle	OBSOLETE. A small subcellular vesicle, or granule, surrounded by a single-layered membrane; formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion.	tmpzr1t_l9r_go_relaxed.owl	secretory vesicle|transition vesicle					This term was made obsolete because it was being used to describe two different components.	GO:0030141|GO:0030133				True			cellular_component											owl:Class	
RO:0002565	biolink:NamedThing	results in movement of		tmpzr1t_l9r_go_relaxed.owl					RO:0002565									external									results_in_movement_of			
GO:0060146	biolink:NamedThing	obsolete host gene silencing in virus induced gene silencing	OBSOLETE. The posttranscriptional gene silencing of host genes that are homologous to viral genes after viral infection.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/19958				The reason for obsoletion is there there is no evidence that this process exists.					True			biological_process											owl:Class	
GO:0044607	biolink:NamedThing	obsolete disruption by symbiont of host endothelial cells	OBSOLETE. Any process in which an organism has a negative effect on the functioning of the host's endothelial cells.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because the cell type should be captured as an annotation extension.		jl	2012-05-30T02:24:50Z		True			biological_process											owl:Class	
GO:0001029	biolink:NamedThing	obsolete RNA polymerase III type 3 promoter TFIIIB-type transcription factor activity	OBSOLETE. Binding to an RNA polymerase III (Pol III) complex, typically composed of seventeen subunits, and with another protein, macromolecule, or complex, permitting those molecules to function in a coordinated way. Once recruited to an RNA polymerase III type 3 promoter by SNAP-type and TFIIIC-type factors, binds to DNA, recruits RNA polymerase III and facilitates the transition from the closed to the open complex.	tmpzr1t_l9r_go_relaxed.owl	RNA polymerase III type 3 promoter polymerase recruiting transcription factor activity							krc	2010-08-23T12:52:40Z		True			molecular_function											owl:Class	
GO:0015176	biolink:NamedThing	obsolete holin	OBSOLETE. Primary function of holins appears to be transport of murein hydrolases across the cytoplasmic membrane to the cell wall of bacteria, where these enzymes hydrolyze the cell wall polymer as a prelude to cell lysis. When chromosomally encoded, these enzymes are therefore autolysins. Holins may also facilitate leakage of electrolytes and nutrients from the cell cytoplasm, thereby promoting cell death. Some catalyze export of nucleases.	tmpzr1t_l9r_go_relaxed.owl	holin					This term was made obsolete because it represents a class of gene products.	GO:0019835				True			molecular_function											owl:Class	
GO:1903289	biolink:NamedThing	obsolete regulation of ATP catabolic process	OBSOLETE. Any process that modulates the frequency, rate or extent of ATP catabolic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of ATP breakdown|regulation of ATP degradation|regulation of ATP catabolism|regulation of ATP hydrolysis					The reason for making this term obsolete is that it gets misused in cases where phosphates are simply being removed from a small molecule. We found no cases where these molecules genuinely underwent catabolism.	GO:0043462	rl	2014-08-11T14:36:39Z		True			biological_process											owl:Class	
GO:0045749	biolink:NamedThing	obsolete negative regulation of S phase of mitotic cell cycle	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of S phase of mitotic cell cycle activity.	tmpzr1t_l9r_go_relaxed.owl	inhibition of S phase of mitotic cell cycle|downregulation of S phase of mitotic cell cycle|down regulation of S phase of mitotic cell cycle|negative regulation of S phase of mitotic cell cycle|down-regulation of S phase of mitotic cell cycle|negative regulation of S-phase of mitotic cell cycle					This term was made obsolete as part of the cell cycle overhaul. This is because it was decided that cell cycle phases are intervals and so cannot be regulated, rather it is the transitions between the phases that are regulated.					True			biological_process											owl:Class	
GO:0006459	biolink:NamedThing	obsolete binding unfolded ER proteins	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	binding unfolded ER proteins					This term was made obsolete because it represents a function rather than a process.	GO:0051082|GO:0005783				True			biological_process											owl:Class	
GO:0052437	biolink:NamedThing	obsolete modulation by organism of defense-related symbiont calcium ion flux	OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of calcium ion fluxes as part of the defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	modulation by organism of defense-related symbiont Ca2+ flux|modulation by organism of defense-related symbiont calcium ion flux					This term was made obsolete because it does not represent a real biological process.					True			biological_process											owl:Class	
GO:0008002	biolink:NamedThing	obsolete lamina lucida	OBSOLETE. The electron-lucent layer of the basal lamina adjacent to the basal plasma membrane of the cells that rest on the lamina.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Lamina_lucida	This term was made obsolete because it is thought to be an experimental artefact.					True			cellular_component											owl:Class	
GO:0052410	biolink:NamedThing	obsolete metabolism by host of symbiont cell wall chitin	OBSOLETE. The chemical reactions and pathways performed by an organism involving chitin in the cell wall of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/21469				This term was obsoleted because it represents a molecular function.					True			biological_process											owl:Class	
GO:1902331	biolink:NamedThing	obsolete DNA strand elongation involved in bacterial-type DNA replication	OBSOLETE. Any DNA strand elongation that is involved in bacterial-type DNA replication.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it does not represent a distinct function from its parent, DNA strand elongation involved in DNA replication.		jl	2013-07-25T10:48:26Z		True			biological_process											owl:Class	
GO:0005321	biolink:NamedThing	obsolete high-density lipoprotein	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	HDL|high-density lipoprotein			GO:0005319		This term was made obsolete because it does not represent a molecular function.					True			molecular_function											owl:Class	
GO:0019269	biolink:NamedThing	obsolete glutamate biosynthetic process, using glutamate synthase (NADPH)	OBSOLETE. The chemical reactions and pathways resulting in the formation of glutamate, catalyzed by the enzyme glutamate synthase (NADPH).	tmpzr1t_l9r_go_relaxed.owl	glutamate formation, using glutamate synthase (NADPH)|glutamate synthesis, using glutamate synthase (NADPH)|glutamate anabolism, using glutamate synthase (NADPH)|glutamate biosynthetic process, using glutamate synthase (NADPH)					This term was made obsolete because it refers to a molecular function.	GO:0004355|GO:0006537				True			biological_process											owl:Class	
GO:0050027	biolink:NamedThing	obsolete L-idonate 2-dehydrogenase activity	OBSOLETE. Catalysis of the reaction: L-idonate + NADP+ = 5-dehydro-D-gluconate + NADPH.	tmpzr1t_l9r_go_relaxed.owl	5KGR|L-idonate 2-dehydrogenase activity|L-idonate:NADP+ 2-oxidoreductase activity|5-ketoglucono-idono-reductase activity|5-keto-D-gluconate 2-reductase activity|reductase, 5-ketogluconate 5- (L-idonate-forming)|5-ketogluconate 2-reductase activity|L-idonate dehydrogenase activity				MetaCyc:L-IDONATE-2-DEHYDROGENASE-RXN|EC:1.1.1.128|RHEA:21176	This term was made obsolete because EC:1.1.1.128 was deleted: the reaction described is covered by EC:1.1.1.264.	GO:0050572				True			molecular_function											owl:Class	
GO:0004217	biolink:NamedThing	obsolete cathepsin L activity	OBSOLETE. Catalysis of the hydrolysis of peptide bonds. Specificity close to that of papain. As compared to cathepsin B, cathepsin L exhibits higher activity towards protein substrates, but has little activity on Z-Arg-Arg-NHMec, and no peptidyl-dipeptidase activity.	tmpzr1t_l9r_go_relaxed.owl	cathepsin L activity|Aldrichina grahami cysteine proteinase			GO:0004197		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:1900621	biolink:NamedThing	obsolete regulation of transcription from RNA polymerase II promoter by calcium-mediated signaling	OBSOLETE. Calcium-mediated signaling that results in regulation of transcription from an RNA polymerase II promoter.	tmpzr1t_l9r_go_relaxed.owl	regulation of transcription from RNA polymerase II promoter, global by calcium-mediated signaling|regulation of global transcription from Pol II promoter by calcium-mediated signaling|regulation of transcription from Pol II promoter by calcium-mediated signaling|regulation of gene-specific transcription from RNA polymerase II promoter by calcium-mediated signaling					This term was obsoleted because it represents a GO-CAM model.	GO:0019722|GO:0006357	bf	2012-05-18T01:00:39Z		True			biological_process											owl:Class	
GO:1990278	biolink:NamedThing	obsolete positive regulation of MBF transcription factor activity	OBSOLETE. Any process that activates or increases the frequency, rate or extent of activity of the transcription factor MBF.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of MBF transcription factor activity					This term was obsoleted at the TermGenie Gatekeeper stage.		al	2014-01-29T14:43:44Z		True			biological_process											owl:Class	
GO:0006510	biolink:NamedThing	obsolete ATP-dependent proteolysis	OBSOLETE. The hydrolysis of a peptide bond or bonds within a protein using energy from the hydrolysis of ATP.	tmpzr1t_l9r_go_relaxed.owl	ATP-dependent peptidolysis|ATP-dependent proteolysis			GO:0004176		This term was made obsolete because it represents a molecular function.	GO:0051603|GO:0006508|GO:0016485				True			biological_process											owl:Class	
GO:1990004	biolink:NamedThing	obsolete XDP phosphatase activity	OBSOLETE. Catalysis of the reaction: XDP + H2O = XMP + phosphate.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/20954				This term was obsoleted because there is no evidence that this reaction exist in vivo.		jl	2012-12-11T14:01:34Z		True			molecular_function											owl:Class	
GO:0030063	biolink:NamedThing	obsolete murein sacculus	OBSOLETE. A structure formed of the cross-linked polymer peptidoglycan (also called murein) that forms a covalently closed net around a bacterial cell, and imparts structural stability to the bacterial cell wall.	tmpzr1t_l9r_go_relaxed.owl	peptidoglycan layer|murein sacculus					This term was made obsolete because it was defined inaccurately.	GO:0009276				True			cellular_component											owl:Class	
GO:0000211	biolink:NamedThing	obsolete protein degradation tagging activity	OBSOLETE. Covalent addition of polyubiquitin to another protein, targeting the tagged protein for destruction.	tmpzr1t_l9r_go_relaxed.owl	protein degradation tagging activity					This term was made obsolete because it represents a biological process and a molecular function.	GO:0005515|GO:0019941				True			molecular_function											owl:Class	
GO:0007397	biolink:NamedThing	obsolete histogenesis and organogenesis	OBSOLETE. The generation of organized tissues or of whole organs.	tmpzr1t_l9r_go_relaxed.owl	histogenesis and organogenesis					This term was made obsolete because more appropriate terms were created.	GO:0009887|GO:0009888				True			biological_process											owl:Class	
GO:0016858	biolink:NamedThing	obsolete racemase and epimerase activity, acting on other compounds	OBSOLETE. Racemase and epimerase activity on compounds other than amino acids, hydroxy acids, carbohydrates or their derivatives.	tmpzr1t_l9r_go_relaxed.owl	racemase and epimerase activity, acting on other compounds					This term was made obsolete because it was an unnecessary grouping term.	GO:0016854				True			molecular_function											owl:Class	
GO:1902719	biolink:NamedThing	obsolete extracellular sequestering of copper ion	OBSOLETE. The process of binding or confining copper ions in an extracellular area such that they are separated from other components of a biological system.	tmpzr1t_l9r_go_relaxed.owl	extracellular sequestering of copper ion					This term was obsoleted at the TermGenie Gatekeeper stage.		mr	2014-02-24T16:09:09Z		True			biological_process											owl:Class	
GO:0061396	biolink:NamedThing	obsolete regulation of transcription from RNA polymerase II promoter in response to copper ion	OBSOLETE. Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter in response to an copper ion stimulus.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it represents a GO-CAM model.	GO:0006357|GO:0071280	dph	2012-01-10T09:07:08Z		True			biological_process											owl:Class	
GO:0019023	biolink:NamedThing	obsolete dsRNA viral genome	OBSOLETE. A viral genome composed of double stranded RNA.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it does not represent a GO cellular component.					True			cellular_component											owl:Class	
GO:0045716	biolink:NamedThing	obsolete positive regulation of low-density lipoprotein particle receptor biosynthetic process	OBSOLETE. Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of low-density lipoprotein receptors.	tmpzr1t_l9r_go_relaxed.owl	upregulation of low-density lipoprotein receptor biosynthetic process|up-regulation of low-density lipoprotein receptor biosynthetic process|stimulation of low-density lipoprotein receptor biosynthetic process|positive regulation of low-density lipoprotein receptor synthesis|activation of low-density lipoprotein receptor biosynthetic process|positive regulation of low-density lipoprotein receptor biosynthesis|positive regulation of low-density lipoprotein receptor anabolism|positive regulation of low-density lipoprotein receptor biosynthetic process|up regulation of low-density lipoprotein receptor biosynthetic process|positive regulation of low-density lipoprotein receptor formation	https://github.com/geneontology/go-ontology/issues/19900				The reason for obsoletion is that those represent specific gene products, and genes annotated to those terms should be annotated to 'regulation of gene expression' or 'regulation of transcription' or some signaling term.					True			biological_process											owl:Class	
GO:0001320	biolink:NamedThing	obsolete age-dependent response to reactive oxygen species involved in chronological cell aging	OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) occurring in non-dividing cells as they age as a result of reactive oxygen species, where the change varies according to the age of the cell or organism.	tmpzr1t_l9r_go_relaxed.owl	age-dependent response to reactive oxygen species during chronological cell ageing|age-dependent response to ROI during chronological cell aging|age-dependent response to reactive oxygen intermediate during chronological cell aging|age-dependent response to ROS during chronological cell aging|age-dependent response to AOS during chronological cell aging|age-dependent response to reactive oxygen species during chronological cell aging|age-dependent response to reactive oxidative species during chronological cell aging|age-dependent response to active oxygen species during chronological cell aging	https://github.com/geneontology/go-ontology/issues/18632				This term was obsoleted because it represent an assay - how long the cell lives -, not a true biological process.	GO:0044838|GO:0090398				True			biological_process											owl:Class	
GO:0015004	biolink:NamedThing	obsolete small blue copper electron carrier	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	small blue copper electron carrier			GO:0009055		This term was made obsolete because it does not represent a molecular function.					True			molecular_function											owl:Class	
GO:1900415	biolink:NamedThing	obsolete regulation of fungal-type cell wall biogenesis by regulation of transcription from RNA polymerase II promoter	OBSOLETE. A regulation of transcription from RNA polymerase II promoter that results in regulation of fungal-type cell wall biogenesis.	tmpzr1t_l9r_go_relaxed.owl	regulation of chitin- and beta-glucan-containing cell wall biogenesis by regulation of transcription from RNA polymerase II promoter					This term was obsoleted because it represents a GO-CAM model.		mah	2012-04-20T03:42:27Z		True			biological_process											owl:Class	
GO:1905783	biolink:NamedThing	obsolete CENP-A containing nucleosome disassembly	OBSOLETE. The disaggregation of a CENP-A containing nucleosome into its constituent components.	tmpzr1t_l9r_go_relaxed.owl	centromere specific nucleosome disassembly|centromere-specific nucleosome disassembly|centromeric nucleosome disassembly	https://github.com/geneontology/go-ontology/issues/22133				This term was obsoleted because it did not describe a different process from that described by its parent.	GO:0006337	vw	2017-01-05T09:19:07Z		True			biological_process											owl:Class	
GO:0035048	biolink:NamedThing	obsolete splicing factor protein import into nucleus	OBSOLETE. The directed movement of a pre-mRNA splicing factor from the cytoplasm into the nucleus, across the nuclear membrane.	tmpzr1t_l9r_go_relaxed.owl	splicing factor protein transport from cytoplasm to nucleus|splicing factor protein-nucleus import					The reason for obsoletion is that all proteins are imported into the nucleus via the same mechanism, so the import of individual proteins should be captured with extensions or by GO-CAM models.	GO:0006606				True			biological_process											owl:Class	
GO:0015356	biolink:NamedThing	obsolete monocarboxylate (lactate, pyruvate, mevalonate) uptake/efflux porter activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	monocarboxylate (lactate, pyruvate, mevalonate) uptake/efflux porter activity					This term was made obsolete because it represents a multifunctional gene product.	GO:0015129|GO:0015562|GO:0015130|GO:0050833				True			molecular_function											owl:Class	
GO:0035969	biolink:NamedThing	obsolete positive regulation of sterol import by positive regulation of transcription from RNA polymerase II promoter	OBSOLETE. Any process that activates or increases the frequency, rate or extent of sterol import by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of sterol uptake by up regulation of transcription from RNA polymerase II promoter|positive regulation of sterol import by up regulation of transcription from RNA polymerase II promoter|positive regulation of sterol uptake by upregulation of transcription from RNA polymerase II promoter|positive regulation of sterol influx by positive regulation of transcription from RNA polymerase II promoter|positive regulation of sterol influx by activation of transcription from RNA polymerase II promoter|positive regulation of sterol influx by up-regulation of transcription from RNA polymerase II promoter|positive regulation of sterol import by stimulation of transcription from RNA polymerase II promoter|positive regulation of sterol import by positive regulation of transcription from Pol II promoter|positive regulation of sterol uptake by stimulation of transcription from RNA polymerase II promoter|positive regulation of sterol influx by stimulation of transcription from RNA polymerase II promoter|positive regulation of sterol uptake by activation of transcription from RNA polymerase II promoter|positive regulation of sterol import by activation of transcription from RNA polymerase II promoter|positive regulation of sterol import by up-regulation of transcription from RNA polymerase II promoter|positive regulation of sterol import by upregulation of transcription from RNA polymerase II promoter|positive regulation of sterol influx by up regulation of transcription from RNA polymerase II promoter|positive regulation of sterol uptake by positive regulation of transcription from RNA polymerase II promoter|positive regulation of sterol uptake by up-regulation of transcription from RNA polymerase II promoter|positive regulation of sterol influx by upregulation of transcription from RNA polymerase II promoter					This term was obsoleted because it represents a GO-CAM model.		bf			True			biological_process											owl:Class	
GO:0051929	biolink:NamedThing	obsolete positive regulation of calcium ion transport via voltage-gated calcium channel activity	OBSOLETE. Any process that activates or increases the frequency, rate or extent of the directed movement of calcium ions via the activity of voltage-gated calcium channels.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of calcium ion transport via voltage gated calcium channel|upregulation of calcium ion transport via voltage gated calcium channel|up regulation of calcium ion transport via voltage gated calcium channel|positive regulation of calcium ion transport via voltage-gated calcium channel activity|activation of calcium ion transport via voltage gated calcium channel|stimulation of calcium ion transport via voltage gated calcium channel|positive regulation of calcium transport via voltage gated calcium channel					This term was made obsolete because it is ill-defined: channel activities are part of ion transport processes, and not the other way round.	GO:0005245				True			biological_process											owl:Class	
GO:1905248	biolink:NamedThing	obsolete regulation of memory	OBSOLETE. Any process that modulates the frequency, rate or extent of memory.	tmpzr1t_l9r_go_relaxed.owl	modulation of memory					This term was obsoleted at the TermGenie Gatekeeper stage.		ha	2016-06-09T13:54:38Z		True			biological_process											owl:Class	
GO:0008944	biolink:NamedThing	obsolete oligopeptidase A activity	OBSOLETE. Catalysis of the hydrolysis of oligopeptides, with broad specificity. Gly or Ala commonly occur as P1 or P1' residues, but more distant residues are also important, as is shown by the fact that Z-Gly-Pro-Gly-Gly-Pro-Ala is cleaved at the Gly-Gly bond, but not Z-(Gly)5.	tmpzr1t_l9r_go_relaxed.owl	68000-M signalpeptide hydrolase activity|oligopeptidase A activity			GO:0004222		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0019795	biolink:NamedThing	obsolete nonprotein amino acid biosynthetic process	OBSOLETE. The chemical reactions and pathways resulting in the formation of any amino acid that does not normally occur as a constituent residue of proteins.	tmpzr1t_l9r_go_relaxed.owl	nonprotein amino acid synthesis|nonprotein amino acid formation|nonprotein amino acid biosynthetic process|nonprotein amino acid biosynthesis|nonprotein amino acid anabolism			GO:0008652		This term was made obsolete because it was a grouping term that was poorly defined and did not provide a particularly meaningful grouping, since even for those amino acids commonly found in proteins, not all molecules necessarily end up incorporated into proteins. The term also violated the principle of positivity.					True			biological_process											owl:Class	
GO:0016025	biolink:NamedThing	obsolete proteasome endopeptidase regulator	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	proteasome endopeptidase regulator					This term was made obsolete because it does not represent a molecular function.	GO:0004175				True			molecular_function											owl:Class	
GO:1903247	biolink:NamedThing	obsolete positive regulation of adrenergic receptor signaling pathway involved in positive regulation of heart rate	OBSOLETE. Any process that activates or increases the frequency, rate or extent of adrenergic receptor signaling pathway involved in positive regulation of heart rate.	tmpzr1t_l9r_go_relaxed.owl	activation of beta adrenergic receptor signaling pathway involved in positive regulation of heart rate|activation of adrenergic receptor signalling pathway involved in positive regulation of heart rate|up-regulation of beta adrenergic receptor signaling pathway involved in positive regulation of heart rate|up-regulation of adenylate cyclase-activating cardiac adrenergic receptor signaling pathway|up regulation of adenylate cyclase-activating cardiac adrenergic receptor signaling pathway|positive regulation of adrenergic receptor signalling pathway involved in positive regulation of heart rate|up-regulation of If activation by beta-adrenergic receptor signaling pathway|up-regulation of adrenergic receptor signalling pathway involved in positive regulation of heart rate|up regulation of Gs-coupled adrenergic receptor signaling pathway involved in positive regulation of heart rate|upregulation of adrenergic receptor signalling pathway involved in positive regulation of heart rate|upregulation of adenylate cyclase-activating cardiac adrenergic receptor signaling pathway|up regulation of adrenergic receptor signalling pathway involved in positive regulation of heart rate|activation of adrenergic receptor signaling pathway involved in positive regulation of heart rate|positive regulation of Gs-coupled adrenergic receptor signaling pathway involved in positive regulation of heart rate|upregulation of activation of funny current by beta-adrenergic receptor signaling pathway|up regulation of activation of funny current by beta-adrenergic receptor signaling pathway|up-regulation of adrenergic receptor signaling pathway involved in positive regulation of heart rate|upregulation of Gs-coupled adrenergic receptor signaling pathway involved in positive regulation of heart rate|upregulation of beta adrenergic receptor signaling pathway involved in positive regulation of heart rate|positive regulation of activation of funny current by beta-adrenergic receptor signaling pathway|positive regulation of If activation by beta-adrenergic receptor signaling pathway|positive regulation of beta adrenergic receptor signaling pathway involved in positive regulation of heart rate|up-regulation of activation of funny current by beta-adrenergic receptor signaling pathway|up regulation of adrenergic receptor signaling pathway involved in positive regulation of heart rate|activation of If activation by beta-adrenergic receptor signaling pathway|upregulation of If activation by beta-adrenergic receptor signaling pathway|positive regulation of adenylate cyclase-activating cardiac adrenergic receptor signaling pathway|activation of adenylate cyclase-activating cardiac adrenergic receptor signaling pathway|up-regulation of Gs-coupled adrenergic receptor signaling pathway involved in positive regulation of heart rate|up regulation of If activation by beta-adrenergic receptor signaling pathway|up regulation of beta adrenergic receptor signaling pathway involved in positive regulation of heart rate|activation of Gs-coupled adrenergic receptor signaling pathway involved in positive regulation of heart rate|activation of activation of funny current by beta-adrenergic receptor signaling pathway|upregulation of adrenergic receptor signaling pathway involved in positive regulation of heart rate	https://github.com/geneontology/go-ontology/issues/14733				This term was obsoleted because it is not precise enough. We must specify if the ACA-activating or ACA inhibiting pathway is the target of the regulation.		rl	2014-08-04T11:54:06Z		True			biological_process											owl:Class	
GO:0085018	biolink:NamedThing	obsolete maintenance of symbiont-containing vacuole by host	OBSOLETE. The process in which a host organism maintains the structure and function of a symbiont-containing vacuole. The symbiont-containing vacuole is a membrane-bounded vacuole within a host cell in which a symbiont organism resides, and can serve to reduce pathogenicity of invading symbionts by restricting them to the vacuolar compartment.	tmpzr1t_l9r_go_relaxed.owl	maintenance of vacuolar integrity during bacterial infection|maintenance of parasitophorous vacuole|maintenance of pathogen-containing vacuole	https://github.com/geneontology/go-ontology/issues/21742				This term has been obsoleted because there is no evidence that this process exists.		jl	2010-05-20T03:58:51Z		True			biological_process											owl:Class	
GO:0051831	biolink:NamedThing	obsolete growth or development in other organism during symbiotic interaction	OBSOLETE. The increase in size or mass of an organism, or the progression of an organism from an initial condition to a later condition, occurring within the cells or tissues of a second organism, where the two organisms are in a symbiotic interaction. This may (but not necessarily) include a filamentous growth form, and also can include secretion of proteases and lipases to break down the tissue of the second organism.	tmpzr1t_l9r_go_relaxed.owl	growth or development within other organism during symbiotic interaction|invasive growth|growth or development in other organism during symbiotic interaction					This term was made obsolete because it contained a conjunction (or).					True			biological_process											owl:Class	
GO:0071445	biolink:NamedThing	obsolete cellular response to protein stimulus	OBSOLETE. Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a protein stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to protein stimulus					This term was made obsolete because more specific terms exist.	GO:0071218|GO:0071345|GO:0034620|GO:0071363|GO:0032870	mah	2009-12-16T04:12:04Z		True			biological_process											owl:Class	
GO:0004274	biolink:NamedThing	obsolete dipeptidyl-peptidase IV activity	OBSOLETE. Catalysis of the release of an N-terminal dipeptide, by the hydrolysis of the Xbb-Xcc bond in Xaa-Xbb-Xcc, preferentially when Xbb is Pro, provided Xcc is neither Pro nor hydroxyproline.	tmpzr1t_l9r_go_relaxed.owl	DPP IV activity|dipeptidyl peptidase IV|dipeptidyl-peptidase IV activity|dipeptidyl-aminopeptidase IV|glycylprolyl dipeptidylaminopeptidase activity|X-PDAP|glycylproline aminopeptidase activity|dipeptidyl-peptide hydrolase activity|glycylprolyl aminopeptidase activity|DPP IV/CD26|post-proline dipeptidyl aminopeptidase IV activity|Gly-Pro naphthylamidase activity|Xaa-Pro-dipeptidylaminopeptidase activity|dipeptidyl aminopeptidase IV activity|pep X|lymphocyte antigen CD26|T cell triggering molecule Tp103|postproline dipeptidyl aminopeptidase IV|glycoprotein GP110|Xaa-Pro-dipeptidyl-aminopeptidase activity|amino acyl-prolyl dipeptidyl aminopeptidase activity|leukocyte antigen CD26				MetaCyc:3.4.14.5-RXN|EC:3.4.14.5	This term was made obsolete because it represents a gene product.	GO:0008236|GO:0008239				True			molecular_function											owl:Class	
GO:0023020	biolink:NamedThing	obsolete regulation of gene expression as a consequence of T cell signal transmission	OBSOLETE. Any process that modulates the frequency, rate or extent of gene expression as a consequence of a process in which a T cell signal is released and/or conveyed from one location to another.	tmpzr1t_l9r_go_relaxed.owl	regulation of gene expression as a consequence of T cell signal transmission					This term was made obsolete because the meaning of the term is ambiguous.	GO:0023019		2010-02-16T09:30:50Z		True			biological_process											owl:Class	
GO:0001128	biolink:NamedThing	obsolete RNA polymerase II transcription coactivator activity involved in preinitiation complex assembly	OBSOLETE. Binding to an RNA polymerase II (RNAP II) regulatory transcription factor and also with the RNAP II basal transcription machinery in order to increase the frequency, rate or stability of the aggregation, arrangement and bonding together of proteins on RNA polymerase II promoter DNA to form the transcriptional preinitiation complex (PIC). Cofactors generally do not bind DNA, but rather mediate protein-protein interactions between activating transcription factors and the basal RNAP II transcription machinery.	tmpzr1t_l9r_go_relaxed.owl	RNA polymerase II transcription coactivator activity involved in preinitiation complex assembly					This term was obsoleted because it represented a mix of function and process and is not annotated consistently		krc	2011-01-20T02:13:36Z		True			molecular_function											owl:Class	
GO:1904546	biolink:NamedThing	obsolete negative regulation of cAMP-dependent protein kinase activity involved in negative regulation of glucose mediated signaling pathway	OBSOLETE. Any negative regulation of cAMP-dependent protein kinase activity that is involved in negative regulation of glucose mediated signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of ATP:protein phosphotransferase (cAMP-dependent) activity involved in down-regulation of glucose mediated signalling|negative regulation of cAMP-dependent protein kinase activity involved in down regulation of glucose mediated signaling pathway|negative regulation of STK22 involved in down-regulation of glucose mediated signaling pathway|negative regulation of protein kinase A activity involved in down-regulation of glucose mediated signalling|negative regulation of adenosine 3',5'-cyclophosphate-dependent protein kinase activity involved in down regulation of glucose mediated signaling pathway|negative regulation of 3',5' cAMP-dependent protein kinase activity involved in negative regulation of glucose mediated signaling pathway|negative regulation of ATP:protein phosphotransferase (cAMP-dependent) activity involved in downregulation of glucose mediated signaling pathway|negative regulation of adenosine 3',5'-cyclophosphate-dependent protein kinase activity involved in downregulation of glucose mediated signalling|negative regulation of 3',5' cAMP-dependent protein kinase activity involved in inhibition of glucose mediated signaling pathway|negative regulation of PKA involved in downregulation of glucose mediated signalling|negative regulation of cyclic AMP-dependent protein kinase activity involved in inhibition of glucose mediated signaling pathway|negative regulation of PKA C involved in negative regulation of glucose mediated signalling|negative regulation of cyclic AMP-dependent protein kinase activity involved in downregulation of glucose mediated signalling|negative regulation of AMPK involved in down regulation of glucose mediated signalling|negative regulation of protein kinase A activity involved in inhibition of glucose mediated signaling pathway|negative regulation of cyclic AMP-dependent protein kinase activity involved in down-regulation of glucose mediated signalling|negative regulation of adenosine 3',5'-cyclophosphate-dependent protein kinase activity involved in down-regulation of glucose mediated signaling pathway|negative regulation of cAMP-dependent protein kinase, intrinsic catalyst activity involved in inhibition of glucose mediated signaling pathway|negative regulation of PKA involved in down-regulation of glucose mediated signaling pathway|negative regulation of AMPK involved in down-regulation of glucose mediated signaling pathway|negative regulation of PKA C involved in down-regulation of glucose mediated signaling pathway|negative regulation of protein kinase A activity involved in down-regulation of glucose mediated signaling pathway|negative regulation of PKA C involved in down regulation of glucose mediated signaling pathway|negative regulation of STK22 involved in down regulation of glucose mediated signalling|negative regulation of protein kinase A activity involved in negative regulation of glucose mediated signaling pathway|negative regulation of adenosine 3',5'-cyclophosphate-dependent protein kinase activity involved in negative regulation of glucose mediated signalling|negative regulation of protein kinase A activity involved in inhibition of glucose mediated signalling|negative regulation of PKA involved in inhibition of glucose mediated signaling pathway|negative regulation of adenosine 3',5'-cyclophosphate-dependent protein kinase activity involved in down regulation of glucose mediated signalling|negative regulation of cAMP-dependent protein kinase, intrinsic catalyst activity involved in negative regulation of glucose mediated signalling|negative regulation of PKA involved in inhibition of glucose mediated signalling|negative regulation of AMPK involved in inhibition of glucose mediated signalling|negative regulation of 3',5' cAMP-dependent protein kinase activity involved in down regulation of glucose mediated signalling|negative regulation of STK22 involved in negative regulation of glucose mediated signaling pathway|negative regulation of PKA C involved in down regulation of glucose mediated signalling|negative regulation of cAMP-dependent protein kinase activity involved in inhibition of glucose mediated signaling pathway|negative regulation of 3',5'-cAMP-dependent protein kinase activity involved in negative regulation of glucose mediated signaling pathway|negative regulation of PKA C involved in downregulation of glucose mediated signalling|negative regulation of cAMP-dependent protein kinase activity involved in downregulation of glucose mediated signalling|negative regulation of 3',5' cAMP-dependent protein kinase activity involved in down-regulation of glucose mediated signaling pathway|negative regulation of AMPK involved in inhibition of glucose mediated signaling pathway|negative regulation of AMPK involved in negative regulation of glucose mediated signaling pathway|negative regulation of cAMP-dependent protein kinase activity involved in negative regulation of glucose mediated signalling|negative regulation of PKA involved in negative regulation of glucose mediated signaling pathway|negative regulation of protein kinase A activity involved in downregulation of glucose mediated signalling|negative regulation of cAMP-dependent protein kinase activity involved in down-regulation of glucose mediated signalling|negative regulation of 3',5' cAMP-dependent protein kinase activity involved in downregulation of glucose mediated signalling|negative regulation of 3',5' cAMP-dependent protein kinase activity involved in inhibition of glucose mediated signalling|negative regulation of 3',5' cAMP-dependent protein kinase activity involved in down-regulation of glucose mediated signalling|negative regulation of AMPK involved in down-regulation of glucose mediated signalling|negative regulation of PKA involved in negative regulation of glucose mediated signalling|negative regulation of ATP:protein phosphotransferase (cAMP-dependent) activity involved in down-regulation of glucose mediated signaling pathway|negative regulation of STK22 involved in downregulation of glucose mediated signaling pathway|negative regulation of PKA involved in down regulation of glucose mediated signaling pathway|negative regulation of cAMP-dependent protein kinase activity involved in down-regulation of glucose mediated signaling pathway|negative regulation of adenosine 3',5'-cyclophosphate-dependent protein kinase activity involved in inhibition of glucose mediated signaling pathway|negative regulation of AMPK involved in downregulation of glucose mediated signalling|negative regulation of cAMP-dependent protein kinase, intrinsic catalyst activity involved in downregulation of glucose mediated signalling|negative regulation of 3',5'-cAMP-dependent protein kinase activity involved in downregulation of glucose mediated signaling pathway|negative regulation of ATP:protein phosphotransferase (cAMP-dependent) activity involved in downregulation of glucose mediated signalling|negative regulation of adenosine 3',5'-cyclophosphate-dependent protein kinase activity involved in down-regulation of glucose mediated signalling|negative regulation of 3',5'-cAMP-dependent protein kinase activity involved in inhibition of glucose mediated signaling pathway|negative regulation of ATP:protein phosphotransferase (cAMP-dependent) activity involved in down regulation of glucose mediated signaling pathway|negative regulation of cyclic AMP-dependent protein kinase activity involved in negative regulation of glucose mediated signalling|negative regulation of AMPK involved in down regulation of glucose mediated signaling pathway|negative regulation of ATP:protein phosphotransferase (cAMP-dependent) activity involved in inhibition of glucose mediated signalling|negative regulation of protein kinase A activity involved in negative regulation of glucose mediated signalling|negative regulation of 3',5' cAMP-dependent protein kinase activity involved in downregulation of glucose mediated signaling pathway|negative regulation of STK22 involved in inhibition of glucose mediated signalling|negative regulation of protein kinase A activity involved in down regulation of glucose mediated signalling|negative regulation of PKA C involved in inhibition of glucose mediated signaling pathway|negative regulation of 3',5'-cAMP-dependent protein kinase activity involved in down-regulation of glucose mediated signalling|negative regulation of STK22 involved in downregulation of glucose mediated signalling|negative regulation of 3',5'-cAMP-dependent protein kinase activity involved in down-regulation of glucose mediated signaling pathway|negative regulation of PKA involved in downregulation of glucose mediated signaling pathway|negative regulation of cAMP-dependent protein kinase, intrinsic catalyst activity involved in downregulation of glucose mediated signaling pathway|negative regulation of cyclic AMP-dependent protein kinase activity involved in down regulation of glucose mediated signalling|negative regulation of PKA C involved in downregulation of glucose mediated signaling pathway|negative regulation of 3',5'-cAMP-dependent protein kinase activity involved in inhibition of glucose mediated signalling|negative regulation of cAMP-dependent protein kinase, intrinsic catalyst activity involved in down-regulation of glucose mediated signaling pathway|negative regulation of 3',5'-cAMP-dependent protein kinase activity involved in down regulation of glucose mediated signaling pathway|negative regulation of cAMP-dependent protein kinase, intrinsic catalyst activity involved in inhibition of glucose mediated signalling|negative regulation of adenosine 3',5'-cyclophosphate-dependent protein kinase activity involved in inhibition of glucose mediated signalling|negative regulation of cAMP-dependent protein kinase, intrinsic catalyst activity involved in down regulation of glucose mediated signalling|negative regulation of AMPK involved in negative regulation of glucose mediated signalling|negative regulation of PKA involved in down-regulation of glucose mediated signalling|negative regulation of cAMP-dependent protein kinase, intrinsic catalyst activity involved in negative regulation of glucose mediated signaling pathway|negative regulation of STK22 involved in inhibition of glucose mediated signaling pathway|negative regulation of ATP:protein phosphotransferase (cAMP-dependent) activity involved in inhibition of glucose mediated signaling pathway|negative regulation of cAMP-dependent protein kinase activity involved in down regulation of glucose mediated signalling|negative regulation of AMPK involved in downregulation of glucose mediated signaling pathway|negative regulation of protein kinase A activity involved in downregulation of glucose mediated signaling pathway|negative regulation of ATP:protein phosphotransferase (cAMP-dependent) activity involved in down regulation of glucose mediated signalling|negative regulation of PKA involved in down regulation of glucose mediated signalling|negative regulation of 3',5' cAMP-dependent protein kinase activity involved in down regulation of glucose mediated signaling pathway|negative regulation of PKA C involved in down-regulation of glucose mediated signalling|negative regulation of ATP:protein phosphotransferase (cAMP-dependent) activity involved in negative regulation of glucose mediated signalling|negative regulation of STK22 involved in down-regulation of glucose mediated signalling|negative regulation of 3',5'-cAMP-dependent protein kinase activity involved in negative regulation of glucose mediated signalling|negative regulation of 3',5' cAMP-dependent protein kinase activity involved in negative regulation of glucose mediated signalling|negative regulation of cyclic AMP-dependent protein kinase activity involved in downregulation of glucose mediated signaling pathway|negative regulation of cAMP-dependent protein kinase activity involved in inhibition of glucose mediated signalling|negative regulation of STK22 involved in negative regulation of glucose mediated signalling|negative regulation of PKA C involved in inhibition of glucose mediated signalling|negative regulation of adenosine 3',5'-cyclophosphate-dependent protein kinase activity involved in downregulation of glucose mediated signaling pathway|negative regulation of STK22 involved in down regulation of glucose mediated signaling pathway|negative regulation of 3',5'-cAMP-dependent protein kinase activity involved in downregulation of glucose mediated signalling|negative regulation of ATP:protein phosphotransferase (cAMP-dependent) activity involved in negative regulation of glucose mediated signaling pathway|negative regulation of cyclic AMP-dependent protein kinase activity involved in inhibition of glucose mediated signalling|negative regulation of cAMP-dependent protein kinase, intrinsic catalyst activity involved in down regulation of glucose mediated signaling pathway|negative regulation of adenosine 3',5'-cyclophosphate-dependent protein kinase activity involved in negative regulation of glucose mediated signaling pathway|negative regulation of cyclic AMP-dependent protein kinase activity involved in negative regulation of glucose mediated signaling pathway|negative regulation of protein kinase A activity involved in down regulation of glucose mediated signaling pathway|negative regulation of 3',5'-cAMP-dependent protein kinase activity involved in down regulation of glucose mediated signalling|negative regulation of cyclic AMP-dependent protein kinase activity involved in down regulation of glucose mediated signaling pathway|negative regulation of cyclic AMP-dependent protein kinase activity involved in down-regulation of glucose mediated signaling pathway|negative regulation of cAMP-dependent protein kinase, intrinsic catalyst activity involved in down-regulation of glucose mediated signalling|negative regulation of PKA C involved in negative regulation of glucose mediated signaling pathway|negative regulation of cAMP-dependent protein kinase activity involved in downregulation of glucose mediated signaling pathway					This term was obsoleted at the TermGenie Gatekeeper stage.		al	2015-08-12T09:48:46Z		True			biological_process											owl:Class	
GO:0008471	biolink:NamedThing	obsolete laccase activity	OBSOLETE. Catalysis of the reaction: 4 benzenediol + O2 = 4 benzosemiquinone + 2 H2O.	tmpzr1t_l9r_go_relaxed.owl	urushiol oxidase activity|urishiol oxidase activity|p-diphenol oxidase activity|benzenediol:oxygen oxidoreductase activity|laccase activity			GO:0016682							True			molecular_function											owl:Class	
GO:0008634	biolink:NamedThing	obsolete negative regulation of survival gene product expression	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of survival gene product expression; survival gene products are those that antagonize the apoptotic program. Regulation can be at the transcriptional, translational, or posttranslational level.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of survival gene product activity|inhibition of survival gene product activity|negative regulation of survival gene product expression|down regulation of survival gene product activity|down-regulation of survival gene product activity|negative regulation of survival gene products|downregulation of survival gene product activity					This term was made obsolete because the meaning of the term is ambiguous: the same gene product may or may not have a role in apoptosis depending on the cell type, tissue type, condition, etc.					True			biological_process											owl:Class	
GO:1902537	biolink:NamedThing	obsolete multi-organism pinocytosis	OBSOLETE. A pinocytosis which involves another organism.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because there is no evidence that this process exists.		jl	2013-12-02T14:14:46Z		True			biological_process											owl:Class	
GO:0051927	biolink:NamedThing	obsolete negative regulation of calcium ion transport via voltage-gated calcium channel activity	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of calcium ions via a voltage-gated calcium channel.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of calcium ion transport via voltage-gated calcium channel activity|downregulation of calcium ion transport via voltage gated calcium channel|down-regulation of calcium ion transport via voltage gated calcium channel|negative regulation of calcium transport via voltage gated calcium channel|down regulation of calcium ion transport via voltage gated calcium channel|inhibition of calcium ion transport via voltage gated calcium channel					This term was made obsolete because it is ill-defined: channel activities are part of ion transport processes, and not the other way round.	GO:0005245				True			biological_process											owl:Class	
GO:0042954	biolink:NamedThing	obsolete lipoprotein transporter activity	OBSOLETE. Enables the directed movement of any conjugated, water-soluble protein in which the nonprotein group consists of a lipid or lipids, into, out of or within a cell, or between cells.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/17004				The reason for obsoletion is this term has been incorrectly used.					True			molecular_function											owl:Class	
GO:0009005	biolink:NamedThing	obsolete signal peptidase II activity	OBSOLETE. Catalysis of the cleavage of N-terminal leader sequences from membrane prolipoproteins. Hydrolyzes the terminal bond of Xaa-Xbb-Xbb-Cys, in which Xaa is hydrophobic (preferably Leu), Xbb is often Ser or Ala, Xcc is often Gly or Ala, and the Cys is alkylated on sulfur with a diacylglyceryl group.	tmpzr1t_l9r_go_relaxed.owl	premurein leader proteinase activity|SPase II activity|signal peptidase II activity|prolipoprotein-signal peptidase activity|lipoprotein signal peptidase activity|prolipoprotein signal peptidase activity|premurein-leader peptidase activity|leader peptidase II			GO:0004190		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0033664	biolink:NamedThing	obsolete positive regulation by symbiont of host defense-related protein level	OBSOLETE. Any process in which the symbiont activates, maintains or increases levels of defense-related proteins in its host. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it is a readout, and annotations should be made to more informative terms.					True			biological_process											owl:Class	
GO:0046238	biolink:NamedThing	obsolete phthalate biosynthetic process	OBSOLETE. The chemical reactions and pathways resulting in the formation of phthalate, any ester or salt of phthalic acid.	tmpzr1t_l9r_go_relaxed.owl	phthalate biosynthesis|phthalate synthesis|phthalate formation|phthalate biosynthetic process|phthalate anabolism			GO:0018963		This term was made obsolete because phthalates are not synthesized by living organisms, and GO does not cover non-biological processes.					True			biological_process											owl:Class	
GO:0001084	biolink:NamedThing	obsolete transcription factor activity, TFIID-class binding	OBSOLETE. Binding to a basal RNA polymerase II transcription factor of the TFIID class in order to modulate transcription. The transcription factor may or may not also interact selectively with DNA as well.	tmpzr1t_l9r_go_relaxed.owl	TFIID-class binding transcription factor activity					This term was obsoleted because it represents two separate functions. The corresponding 'binding' term should be used in combination with a transcription regulator activity child.	GO:0001094	krc	2010-10-27T04:15:22Z		True			molecular_function											owl:Class	
GO:0000204	biolink:NamedThing	obsolete activation of MAPKK during sporulation (sensu Saccharomyces)	OBSOLETE. Upregulation of a MAP kinase kinase in the context of sporulation. As in, but not restricted to, the taxon Saccharomyces (Saccharomyces, ncbi_taxonomy_id:4930).	tmpzr1t_l9r_go_relaxed.owl	activation of MAPKK during sporulation (sensu Saccharomyces)					This term was made obsolete because it is a gene product specific term.					True			biological_process											owl:Class	
GO:0042980	biolink:NamedThing	obsolete cystic fibrosis transmembrane conductance regulator binding	OBSOLETE. Binding to a Cystic Fibrosis Transmembrane conductance Regulator (CFTR) protein.	tmpzr1t_l9r_go_relaxed.owl	CFTR binding|cystic fibrosis transmembrane conductance regulator binding			GO:0044325		This term was made obsolete because it represents binding to an individual protein.					True			molecular_function											owl:Class	
GO:0046259	biolink:NamedThing	obsolete trinitrotoluene biosynthetic process	OBSOLETE. The chemical reactions and pathways resulting in the formation of trinitrotoluene, a methylated benzene molecule with three NO2 groups attached to it.	tmpzr1t_l9r_go_relaxed.owl	trinitrotoluene biosynthesis|trinitrotoluene biosynthetic process|trinitrotoluene formation|trinitrotoluene synthesis|trinitrotoluene anabolism			GO:0018973		This term was made obsolete because trinitrotoluene is not synthesized by living organisms, and GO does not cover non-biological processes.					True			biological_process											owl:Class	
GO:1900402	biolink:NamedThing	obsolete regulation of carbohydrate metabolic process by regulation of transcription from RNA polymerase II promoter	OBSOLETE. A regulation of transcription from RNA polymerase II promoter that results in regulation of carbohydrate metabolic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of carbohydrate metabolism by regulation of transcription from RNA polymerase II promoter					This term was obsoleted because it represents a GO-CAM model.		mah	2012-04-20T02:45:27Z		True			biological_process											owl:Class	
GO:0052375	biolink:NamedThing	obsolete evasion or tolerance by organism of symbiont-produced nitric oxide	OBSOLETE. The process by which an organism avoids the effects of nitric oxide produced as a defense response by the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	evasion or tolerance by organism of symbiont NO|evasion or tolerance by organism of symbiont-produced nitric oxide|evasion or tolerance by organism of symbiont nitric oxide|evasion or tolerance of NO produced by symbiont in response to organism|evasion or tolerance by organism of symbiont-produced NO|evasion or tolerance of nitric oxide produced by symbiont in response to organism					This term was made obsolete because it does not represent a real biological process.					True			biological_process											owl:Class	
RO:0002341	biolink:NamedThing	results in transport along		tmpzr1t_l9r_go_relaxed.owl					RO:0002341									external									results_in_transport_along			
GO:1905452	biolink:NamedThing	obsolete canonical Wnt signaling pathway involved in regulation of stem cell proliferation	OBSOLETE. Any canonical Wnt signaling pathway that is involved in regulation of stem cell proliferation.	tmpzr1t_l9r_go_relaxed.owl	Wnt receptor signalling pathway through beta-catenin involved in regulation of stem cell proliferation|canonical Wnt receptor signaling pathway involved in regulation of stem cell proliferation|frizzled-1 receptor signaling pathway involved in regulation of stem cell proliferation|canonical Wnt-activated signaling pathway involved in regulation of stem cell proliferation|Wnt receptor signaling pathway through beta-catenin involved in regulation of stem cell proliferation|Wnt receptor signaling pathway via beta-catenin involved in regulation of stem cell proliferation					This term was obsoleted at the TermGenie Gatekeeper stage.		bc	2016-09-16T11:52:42Z		True			biological_process											owl:Class	
GO:0010926	biolink:NamedThing	obsolete anatomical structure formation	OBSOLETE. The process pertaining to the initial formation of an anatomical structure from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structure is recognizable. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome.	tmpzr1t_l9r_go_relaxed.owl	anatomical structure formation					The reason for obsoletion is that the term is confusing - it sounds developmental and has a developmental sounding def, but it is not a child of developmental process and its children included 'cellular component assembly'. The term was created to group together 'cellular component assembly' and 'anatomical structure formation involved in morphogenesis', but we no longer feel that this grouping is useful.	GO:0048646|GO:0022607				True			biological_process											owl:Class	
GO:0005039	biolink:NamedThing	obsolete death receptor-associated factor activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	death receptor-associated factor activity					This term was made obsolete because it represents a gene product and not a molecular function.	GO:0005515|GO:0005123				True			molecular_function											owl:Class	
RO:0002591	biolink:NamedThing	results in remodeling of		tmpzr1t_l9r_go_relaxed.owl					RO:0002591									external									results_in_remodeling_of			
GO:0000174	biolink:NamedThing	obsolete inactivation of MAPK (mating sensu Saccharomyces)	OBSOLETE. Downregulation of MAP kinase activity in the context of transduction of mating pheromone signal, as described for Saccharomyces.	tmpzr1t_l9r_go_relaxed.owl	inactivation of MAPK (mating sensu Saccharomyces)			GO:0000750		This term was made obsolete because it is a gene product specific term.					True			biological_process											owl:Class	
GO:0006371	biolink:NamedThing	obsolete mRNA splicing	OBSOLETE. The process in which excision of introns from the primary transcript of messenger RNA (mRNA) is followed by ligation of the two exon termini exposed by removal of each intron, so that mRNA consisting only of the joined exons is produced.	tmpzr1t_l9r_go_relaxed.owl	mRNA splicing					This term was made obsolete because it represents several different processes.	GO:0000398|GO:0000374|GO:0000394|GO:0000372|GO:0000373				True			biological_process											owl:Class	
GO:0051184	biolink:NamedThing	obsolete cofactor transmembrane transporter activity	OBSOLETE. Enables the transfer of a cofactor from one side of a membrane to the other. A cofactor is a substance that is required for the activity of an enzyme or other protein.	tmpzr1t_l9r_go_relaxed.owl	vitamin or cofactor transporter activity|cofactor transporter activity					1. Making inferences in GO about compounds based on the cofactor role curated by ChEBI creates relationships that are not always true which violates ontological principles for GO; therefore we will cease making these inferences. 2. It is not meaningful to group transport processes that are not all chemically related by the fact that they may be used as a cofactor.					True			molecular_function											owl:Class	
GO:1900008	biolink:NamedThing	obsolete negative regulation of extrachromosomal rDNA circle accumulation involved in replicative cell aging	OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of extrachromosomal rDNA circle accumulation involved in replicative cell aging.	tmpzr1t_l9r_go_relaxed.owl	down regulation of extrachromosomal rDNA circle accumulation during replicative cell aging|down regulation of extrachromosomal rDNA circle accumulation during replicative cell ageing|negative regulation of extrachromosomal rDNA circle accumulation during replicative cell aging|negative regulation of extrachromosomal rDNA circle accumulation during replicative cell ageing|negative regulation of extrachromosomal ribosomal DNA circle accumulation during replicative cell aging|down regulation of extrachromosomal ribosomal DNA circle accumulation during replicative cell aging|down regulation of extrachromosomal rDNA circle accumulation involved in replicative cell aging	https://github.com/geneontology/go-ontology/issues/20007				This term was obsoleted because it represents an assay, not a true biological process.		se	2012-01-09T10:44:10Z		True			biological_process											owl:Class	
GO:0036251	biolink:NamedThing	obsolete positive regulation of transcription from RNA polymerase II promoter in response to salt stress	OBSOLETE. Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is under salt stress. The stress is usually an increase or decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/12739				This term was obsoleted because it represents a GO-CAM model.	GO:0071472|GO:0045944	bf	2012-06-12T11:38:22Z		True			biological_process											owl:Class	
GO:0072421	biolink:NamedThing	obsolete detection of DNA damage stimulus involved in DNA damage checkpoint	OBSOLETE. The series of events in which information about damage to DNA is received and converted into a molecular signal, contributing to a DNA damage checkpoint.	tmpzr1t_l9r_go_relaxed.owl	DNA damage checkpoint sensor process|DNA damage checkpoint sensor mechanism|sensing involved in DNA damage checkpoint	https://github.com/geneontology/go-ontology/issues/20976				This term was obsoleted because it corresponds to a molecular function.		mah	2010-12-08T04:16:04Z		True			biological_process											owl:Class	
GO:0071508	biolink:NamedThing	obsolete activation of MAPK activity involved in conjugation with cellular fusion	OBSOLETE. Any process that initiates the activity of the inactive enzyme MAP kinase in the context of conjugation with cellular fusion.	tmpzr1t_l9r_go_relaxed.owl	conjugation with cellular fusion, activation of MAPK activity|activation of MAPK activity involved in mating response	https://github.com/geneontology/go-ontology/issues/20242				This term was obsoleted because it represents a GO-CAM model.		mah	2010-01-05T02:09:35Z		True			biological_process											owl:Class	
GO:0090145	biolink:NamedThing	obsolete mitochondrial nucleoid organization involved in mitochondrial fission	OBSOLETE. A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the mitochondrial nucleoid that contributes to mitochondrial division.	tmpzr1t_l9r_go_relaxed.owl	mitochondrial nucleoid organisation involved in mitochondrial fission	https://github.com/geneontology/go-ontology/issues/18417				This term was obsoleted because it represented a phenotype.	GO:0000266|GO:0000002	tb	2009-12-08T02:39:34Z		True			biological_process											owl:Class	
GO:0009472	biolink:NamedThing	obsolete cytochrome c3 (tetraheme)	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	cytochrome c3 (tetraheme)					This term was made obsolete because it represents a gene product.	GO:0009055				True			molecular_function											owl:Class	
GO:0019446	biolink:NamedThing	obsolete tyrosine catabolic process to phosphoenolpyruvate	OBSOLETE. The chemical reactions and pathways resulting in the breakdown of tyrosine into other compounds, including phosphoenolpyruvate.	tmpzr1t_l9r_go_relaxed.owl	tyrosine breakdown to phosphoenolpyruvate|tyrosine degradation to phosphoenolpyruvate					The reason for obsoletion is that there is no evidence that this is a real process.					True			biological_process											owl:Class	
GO:0030019	biolink:NamedThing	obsolete tryptase activity	OBSOLETE. Catalysis of the preferential cleavage of Arg-Xaa, Lys-Xaa, but with more restricted specificity than trypsin.	tmpzr1t_l9r_go_relaxed.owl	tryptase activity|pituitary tryptase activity|mast cell serine proteinase tryptase activity|mast cell serine proteinase II|mast cell protease II activity|lung tryptase activity|skin tryptase activity|mast cell tryptase activity|rat mast cell protease II|mast cell proteinase II|mast cell neutral proteinase activity|tryptase M			GO:0004252		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:1903992	biolink:NamedThing	obsolete regulation of protein stabilization	OBSOLETE. Any process that modulates the frequency, rate or extent of protein stabilization.	tmpzr1t_l9r_go_relaxed.owl	regulation of protein stabilization|regulation of lysosomal protein stabilization|regulation of positive regulation of protein stability|regulation of protein sequestering|regulation of protein stabilization activity					This term was made obsolete because it was created in error.	GO:0031647	pga	2015-03-05T13:32:49Z		True			biological_process											owl:Class	
GO:2000531	biolink:NamedThing	obsolete regulation of fatty acid biosynthetic process by regulation of transcription from RNA polymerase II promoter	OBSOLETE. Any process that modulates the frequency, rate or extent of the biosynthesis of fatty acids, by modulating the frequency, rate or extent of transcription from an RNA polymerase II promoter.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it represents a GO-CAM model.		dph	2011-03-24T12:18:33Z		True			biological_process											owl:Class	
GO:0005012	biolink:NamedThing	obsolete Neu/ErbB-2 receptor activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	Neu/ErbB-2 receptor activity					This term was made obsolete because it represents a class of receptor rather than an activity.	GO:0043125				True			molecular_function											owl:Class	
GO:0038069	biolink:NamedThing	obsolete MAP kinase phosphatase activity involved in regulation of cell wall biogenesis	OBSOLETE. Catalysis of the reaction: a phosphorylated MAP kinase + H2O = a MAP kinase + phosphate, where the MAP kinase (MAPK) is part of a MAPK signaling cascade that contributes to cell wall biogenesis.	tmpzr1t_l9r_go_relaxed.owl	Mpk1 phosphatase activity|Slt2 phosphatase activity					This term has been obsoleted because it represents a GO-CAM model rather than a single GO term.		bf	2012-01-25T03:38:58Z		True			molecular_function											owl:Class	
GO:0052504	biolink:NamedThing	obsolete positive regulation by organism of defense-related symbiont callose deposition	OBSOLETE. Any process by which an organism activates, maintains or increases the frequency, rate or extent of callose deposition by the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	positive regulation by organism of defense-related papilla formation in symbiont|positive regulation by organism of defense-related symbiont callose deposition|induction by organism of defense-related symbiont callose deposition|induction by organism of defense-related papilla formation in symbiont					This term was made obsolete because it does not represent a real biological process.					True			biological_process											owl:Class	
GO:0052520	biolink:NamedThing	obsolete positive regulation by organism of nutrient release from other organism involved in symbiotic interaction	OBSOLETE. Any process in which an organism activates, maintains or increases the frequency, rate or extent of the release of nutrients from a second organism, where the two organisms are in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	activation by organism of nutrient release from other organism during symbiotic interaction|positive regulation by organism of nutrient release from other organism during symbiotic interaction|upregulation by organism of nutrient release from other organism during symbiotic interaction|stimulation by organism of nutrient release from other organism during symbiotic interaction|promotion of nutrient release from other organism|up regulation by organism of nutrient release from other organism during symbiotic interaction|up-regulation by organism of nutrient release from other organism during symbiotic interaction					This term was obsoleted because it represents an unnecessary grouping class.					True			biological_process											owl:Class	
GO:1902032	biolink:NamedThing	obsolete regulation of transcription from RNA polymerase II promoter involved in response to osmotic stress	OBSOLETE. Any regulation of transcription from RNA polymerase II promoter that is involved in response to osmotic stress.	tmpzr1t_l9r_go_relaxed.owl	regulation of transcription from RNA polymerase II promoter involved in response to osmotic stress|regulation of gene-specific transcription from RNA polymerase II promoter involved in response to osmotic stress|global transcription regulation from Pol II promoter involved in response to osmotic stress|regulation of gene-specific transcription from RNA polymerase II promoter involved in osmotic stress response|regulation of global transcription from Pol II promoter involved in response to osmotic stress|regulation of transcription from RNA polymerase II promoter involved in osmotic response|regulation of transcription from RNA polymerase II promoter, global involved in osmotic stress response|regulation of transcription from Pol II promoter involved in osmotic stress response|regulation of transcription from RNA polymerase II promoter, global involved in osmotic response|regulation of transcription from RNA polymerase II promoter involved in osmotic stress response|regulation of global transcription from Pol II promoter involved in osmotic stress response|regulation of transcription from Pol II promoter involved in osmotic response|regulation of transcription from RNA polymerase II promoter, global involved in response to osmotic stress|global transcription regulation from Pol II promoter involved in osmotic stress response|global transcription regulation from Pol II promoter involved in osmotic response|regulation of transcription from Pol II promoter involved in response to osmotic stress|regulation of gene-specific transcription from RNA polymerase II promoter involved in osmotic response|regulation of global transcription from Pol II promoter involved in osmotic response					This term was obsoleted at the TermGenie Gatekeeper stage.	GO:0006970|GO:0006357	kmv	2013-04-01T17:24:04Z		True			biological_process											owl:Class	
GO:0097606	biolink:NamedThing	obsolete positive regulation of nuclear envelope permeability	OBSOLETE. Any process that increases the frequency, rate or extent of the passage or uptake of molecules by the nuclear envelope.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of nuclear membrane permeability					The reason for obsoletion is that the nuclear envelope is quite permeable, so there is no cellular process to regulate it.		pr	2014-05-14T15:43:06Z		True			biological_process											owl:Class	
GO:0006373	biolink:NamedThing	obsolete 3'-splice site cleavage, exon ligation	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	3'-splice site cleavage, exon ligation					This term was made obsolete because it represents a molecular function.	GO:0000386|GO:0000393|GO:0000388				True			biological_process											owl:Class	
GO:0071533	biolink:NamedThing	obsolete ankyrin repeat-mediated complex assembly	OBSOLETE. A process of protein complex assembly in which the arrangement and bonding together of the set of components that form the protein complex is mediated by an ankyrin repeat interaction.	tmpzr1t_l9r_go_relaxed.owl	ANK repeat-mediated complex assembly					This term was obsoleted because it represented a molecular function (binding), not a biological process.  The term represented a domain involved in protein-protein interactions, but no necessarily the process of assembling a complex.		mah	2010-01-08T02:27:56Z		True			biological_process											owl:Class	
GO:0016678	biolink:NamedThing	obsolete oxidoreductase activity, acting on heme group of donors, other acceptors	OBSOLETE. Catalysis of an oxidation-reduction (redox) reaction in which a heme group acts as a hydrogen or electron donor and reduces an acceptor other than a nitrogenous group or oxygen.	tmpzr1t_l9r_go_relaxed.owl	oxidoreductase activity, acting on heme group of donors, other acceptors|oxidoreductase activity, acting on haem group of donors, other acceptors					This term was made obsolete because it was an unnecessary grouping term.	GO:0016675				True			molecular_function											owl:Class	
GO:0075101	biolink:NamedThing	obsolete negative regulation by host of symbiont protein kinase-mediated signal transduction	OBSOLETE. Any process in which the host organism stops, prevents, or reduces the frequency, rate or extent of protein kinase-mediated signal transduction in the symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl						The reason for obsoletion is that there is no evidence that the host can modulate or regulate a symbiont's signal transduction pathway.					True			biological_process											owl:Class	
GO:0007069	biolink:NamedThing	obsolete negative regulation of transcription from RNA polymerase I promoter during mitotic cell cycle	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of transcription from an RNA polymerase I promoter that occurs during the mitotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl	downregulation of transcription from RNA polymerase I promoter during mitosis|down regulation of transcription from RNA polymerase I promoter during mitosis|negative regulation of transcription from Pol I promoter during mitosis|inhibition of transcription from RNA polymerase I promoter during mitosis|negative regulation of transcription from RNA polymerase I promoter, mitotic|down-regulation of transcription from RNA polymerase I promoter during mitosis|mitotic repression of transcription from Pol I promoter	https://github.com/geneontology/go-ontology/issues/14896				The reason for obsoletion is that 'during' should be captured using an annotation extension.	GO:0016479|GO:0044772				True			biological_process											owl:Class	
GO:0031277	biolink:NamedThing	obsolete positive regulation of lateral pseudopodium assembly	OBSOLETE. Any process that activates or increases the frequency, rate or extent of the assembly of pseudopodia from the lateral side of the cell.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of lateral pseudopodium formation|up regulation of lateral pseudopodium formation|stimulation of lateral pseudopodium formation|activation of lateral pseudopodium formation|up-regulation of lateral pseudopodium formation|upregulation of lateral pseudopodium formation	https://github.com/geneontology/go-ontology/issues/21738				The regulation of lateral pseudopodium assembly terms were not used consistently. The negative regulation term has been replaced by GO:0120320 lateral pseudopodium retraction.					True			biological_process											owl:Class	
GO:0075169	biolink:NamedThing	obsolete positive regulation of symbiont protein kinase-mediated signal transduction in response to host	OBSOLETE. Any process in which the symbiont organism activates, maintains or increases the frequency, rate or extent of its protein kinase-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because there is no evidence that this process exists.					True			biological_process											owl:Class	
GO:1903159	biolink:NamedThing	obsolete malate transmembrane transporter activity involved in malate import into cell	OBSOLETE. Any malate transmembrane transporter activity that is involved in malate import into cell.	tmpzr1t_l9r_go_relaxed.owl	malate transmembrane transporter activity involved in malate import into cell|dicarboxylate (succinate/fumarate/malate) antiporter activity involved in malate import into cell					This term was obsoleted at the TermGenie Gatekeeper stage.		dos	2014-07-09T11:56:27Z		True			molecular_function											owl:Class	
GO:0061741	biolink:NamedThing	obsolete chaperone-mediated protein transport involved in chaperone-mediated autophagy	OBSOLETE. The chaperone-mediated protein transport process in which a protein that is bound to a chaperone and a lysosomal receptor is unfolded and transported into the lysosome as part of chaperone-mediated autophagy.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/20850				This term was obsoleted because it represents a function within a process.		dph	2015-10-21T08:56:33Z		True			biological_process											owl:Class	
GO:0090007	biolink:NamedThing	obsolete regulation of mitotic anaphase	OBSOLETE. Any process that modulates the frequency, rate or extent of mitotic anaphase, a cell cycle process comprising the steps by which a cell progresses through anaphase, the stage of mitosis during which the two sets of chromosomes separate and move away from each other.	tmpzr1t_l9r_go_relaxed.owl	regulation of mitotic anaphase					This term was made obsolete as part of the cell cycle overhaul. This is because it was decided that cell cycle phases are intervals and so cannot be regulated, rather it is the transitions between the phases that are regulated.		tb	2009-07-17T01:08:58Z		True			biological_process											owl:Class	
GO:0004428	biolink:NamedThing	obsolete inositol or phosphatidylinositol kinase activity	OBSOLETE. Catalysis of the phosphorylation of myo-inositol (1,2,3,5/4,6-cyclohexanehexol) or a phosphatidylinositol.	tmpzr1t_l9r_go_relaxed.owl	inositol or phosphatidylinositol kinase activity|inositol/phosphatidylinositol kinase activity					This term was made obsolete because it is a grouping term representing two quite different sets of entities, hexose sugars and glycerophospholipids.	GO:0052742|GO:0019140|GO:0052813|GO:0016307				True			molecular_function											owl:Class	
GO:0052204	biolink:NamedThing	obsolete negative regulation of molecular function in other organism involved in symbiotic interaction	OBSOLETE. Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of the functional activity of proteins in a second organism, where the two organisms are in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of protein function in other organism during symbiotic interaction|inhibition of protein function in other organism during symbiotic interaction|inhibition of protein function in other organism|downregulation of protein function in other organism during symbiotic interaction|down regulation of protein function in other organism during symbiotic interaction|down-regulation of protein function in other organism during symbiotic interaction					This term was obsoleted because it represents an unnecessary grouping class.					True			biological_process											owl:Class	
GO:0008319	biolink:NamedThing	obsolete prenyl protein specific endopeptidase activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	prenyl protein specific endopeptidase activity			GO:0004222		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0019011	biolink:NamedThing	obsolete DNA replication accessory factor	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	DNA replication accessory factor					This term was made obsolete because it does not represent a true molecular function.	GO:0006260				True			molecular_function											owl:Class	
GO:0047687	biolink:NamedThing	obsolete ascorbate 2,3-dioxygenase activity	OBSOLETE. Catalysis of the reaction: L-ascorbate + H(2)O + O(2) = L-threonate + 2 H(+) + oxalate.	tmpzr1t_l9r_go_relaxed.owl	ascorbate 2,3-dioxygenase activity|AAoxygenase activity|ascorbate:oxygen 2,3-oxidoreductase (bond-cleaving)				MetaCyc:ASCORBATE-23-DIOXYGENASE-RXN|KEGG_REACTION:R00646|RHEA:21784	This term was made obsolete because EC:1.13.11.13 was deleted; the activity is the sum of several enzymatic and spontaneous reactions.					True			molecular_function											owl:Class	
GO:0000261	biolink:NamedThing	obsolete sodium-translocating V-type ATPase activity	OBSOLETE. Catalysis of the reaction: ATP + H2O + Na+(in) = ADP + phosphate + Na+(out). Found in vacuoles of eukaryotes and in bacteria.	tmpzr1t_l9r_go_relaxed.owl	sodium-translocating V-type ATPase activity			GO:0046962		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:1990561	biolink:NamedThing	obsolete regulation of transcription from RNA polymerase II promoter in response to copper ion starvation	OBSOLETE. Modulation of the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is deprived of copper ions.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it represents a GO-CAM model.	GO:0035874|GO:0006357	al	2014-11-25T14:21:55Z		True			biological_process											owl:Class	
GO:0023065	biolink:NamedThing	obsolete signal transmission via blood	OBSOLETE. The process in which a signal is conveyed via blood.	tmpzr1t_l9r_go_relaxed.owl	signal transmission via blood					This term was made obsolete because the meaning of the term is ambiguous.	GO:0010232|GO:0023052		2010-02-16T09:30:50Z		True			biological_process											owl:Class	
GO:0005209	biolink:NamedThing	obsolete plasma protein	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	plasma protein					This term was made obsolete because it describes presence in body fluids rather than an activity.					True			molecular_function											owl:Class	
GO:0003801	biolink:NamedThing	obsolete blood coagulation factor activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	blood coagulation factor activity					This term was made obsolete because it refers to involvement in a biological process.	GO:0004252|GO:0007596				True			molecular_function											owl:Class	
GO:0008464	biolink:NamedThing	obsolete gamma-glutamyl hydrolase activity	OBSOLETE. Catalysis of the cleavage of a gamma-glutamyl bond to release an unsubstituted C-terminal amino acid.	tmpzr1t_l9r_go_relaxed.owl	folic acid conjugase activity|pteroyl-poly-gamma-glutamate hydrolase activity|lysosomal gamma-glutamyl carboxypeptidase activity|conjugase activity|gamma-glutamyl hydrolase activity|polyglutamate hydrolase activity|gamma-Glu-X carboxypeptidase activity|poly(glutamic acid) hydrolase II|pteroylpoly-gamma-glutamyl hydrolase activity|carboxypeptidase G activity|poly(gamma-glutamic acid) endohydrolase activity|pteroyl-poly-alpha-glutamate hydrolase activity|folate conjugase activity			GO:0008242		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0003804	biolink:NamedThing	obsolete coagulation factor Xa activity	OBSOLETE. Catalysis of the preferential cleavage of Arg-Thr and then Arg-Ile bonds in prothrombin to form thrombin, and on factor VII, which it converts to a two-chain form (factor VIIa).	tmpzr1t_l9r_go_relaxed.owl	blood coagulation factor X activity|plasma thromboplastin|activated Stuart-Prower factor|factor Xa|thromboplastin|activated factor X|prothrombase activity|thrombokinase activity|coagulation factor Xa activity|activated blood-coagulation factor X|autoprothrombin C|Stuart factor activity|Stuart factor|prothrombinase activity			GO:0004252		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0039571	biolink:NamedThing	obsolete suppression by virus of host STAT1 activity by negative regulation of STAT1 tyrosine phosphorylation	OBSOLETE. Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host STAT1 (signal transducer and activator of transcription-1) activity by stopping, preventing, or reducing the frequency, rate or extent of the introduction of a phosphate group to a tyrosine residue of a STAT1 protein. For example, the measles virus V protein inhibits tyrosine phosphorylation of STAT1, thereby preventing STAT1 activation.	tmpzr1t_l9r_go_relaxed.owl	inhibition by virus of tyrosine phosphorylation of STAT1					The reason for obsoleting this term is that it is too specific. The exact molecular roles of the individual proteins should be captured separately.		bf	2012-03-12T04:50:38Z		True			biological_process											owl:Class	
GO:0051849	biolink:NamedThing	obsolete active evasion of symbiont immune response via regulation of symbiont antigen processing and presentation	OBSOLETE. Any mechanism of active immune avoidance which works by regulating the symbiont's antigen processing or presentation pathways, e.g. by blocking any stage in MHC class II presentation. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	active evasion of symbiont immune response via regulation of symbiont antigen processing and presentation|active immune evasion via modulation of symbiont antigen processing and presentation|active immune evasion via regulation of symbiont antigen processing or presentation|active evasion of symbiont immune response via regulation of symbiont antigen processing and presentation pathway|active immune evasion via modulation of symbiont antigen processing/presentation					This term was made obsolete because it does not represent a real process that exists in nature.					True			biological_process											owl:Class	
GO:2000745	biolink:NamedThing	obsolete positive regulation of transcription from RNA polymerase III promoter involved in smooth muscle cell differentiation	OBSOLETE. Any positive regulation of transcription from RNA polymerase III promoter that is involved in smooth muscle cell differentiation.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of transcription from RNA polymerase III promoter involved in smooth muscle cell differentiation|stimulation of transcription from RNA polymerase III promoter of smooth muscle cell differentiation|positive regulation of transcription from RNA polymerase III promoter of smooth muscle cell differentiation|up regulation of transcription from RNA polymerase III promoter of smooth muscle cell differentiation|upregulation of transcription from RNA polymerase III promoter of nonstriated muscle cell differentiation|up-regulation of transcription from RNA polymerase III promoter of smooth muscle cell differentiation|positive regulation of transcription from Pol III promoter of smooth muscle cell differentiation|activation of transcription from RNA polymerase III promoter of smooth muscle cell differentiation|positive regulation of transcription from RNA polymerase III promoter of nonstriated muscle cell differentiation|up regulation of transcription from RNA polymerase III promoter of nonstriated muscle cell differentiation|upregulation of transcription from RNA polymerase III promoter of smooth muscle cell differentiation|up-regulation of transcription from RNA polymerase III promoter of nonstriated muscle cell differentiation|activation of transcription from RNA polymerase III promoter of nonstriated muscle cell differentiation|positive regulation of transcription from Pol III promoter of nonstriated muscle cell differentiation|stimulation of transcription from RNA polymerase III promoter of nonstriated muscle cell differentiation					This term was made obsolete because it was added in error.	GO:0051145|GO:0048665	bf	2011-06-15T10:03:19Z		True			biological_process											owl:Class	
GO:0100050	biolink:NamedThing	obsolete negative regulation of mating type switching by transcription from RNA polymerase II promoter	OBSOLETE. Any transcription from RNA polymerase II promoter process that negatively regulates mating type switching.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it represents a GO-CAM model.		cjm	2015-04-02T04:13:19Z		True			biological_process											owl:Class	
GO:0001688	biolink:NamedThing	obsolete cytoplasmic dynein intermediate chain	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	cytoplasmic dynein intermediate chain			GO:0005868		This term was made obsolete because it represents a single gene product and not a complex.					True			cellular_component											owl:Class	
GO:0052015	biolink:NamedThing	obsolete catabolism by symbiont of host carbohydrate	OBSOLETE. The chemical reactions and pathways performed by an organism resulting in the breakdown of carbohydrate molecules within the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	catabolism by organism of host carbohydrate	https://github.com/geneontology/go-ontology/issues/21469				This term was obsoleted because it represents a molecular function.					True			biological_process											owl:Class	
GO:0032234	biolink:NamedThing	obsolete regulation of calcium ion transport via store-operated calcium channel activity	OBSOLETE. Any process that modulates the frequency, rate or extent of the directed movement of calcium ions via a store-operated calcium channel.	tmpzr1t_l9r_go_relaxed.owl	regulation of calcium ion transport via store-operated calcium channel activity|regulation of calcium transport via store-operated calcium channel|regulation of store-operated calcium channel activity					This term was made obsolete because it is ill-defined: channel activities are part of ion transport processes, and not the other way round.	GO:0015279				True			biological_process											owl:Class	
GO:0009109	biolink:NamedThing	obsolete coenzyme catabolic process	OBSOLETE. The chemical reactions and pathways resulting in the breakdown of coenzymes, any of various nonprotein organic cofactors that are required, in addition to an enzyme and a substrate, for an enzymatic reaction to proceed.	tmpzr1t_l9r_go_relaxed.owl	coenzyme degradation|coenzyme and prosthetic group catabolic process|coenzyme breakdown|coenzyme catabolism|coenzyme and prosthetic group catabolism					1. Making inferences in GO about compounds based on the coenzyme role curated by ChEBI creates relationships that are not always true which violates ontological principles for GO; therefore we will cease making these inferences. 2. It is not meaningful to group catabolic processes that are not all metabolically related by the fact that they may be used as a coenzyme.					True			biological_process											owl:Class	
GO:0075068	biolink:NamedThing	obsolete growth or development of symbiont in host vascular tissue	OBSOLETE. The increase in size or mass of symbiont, or the progression of the symbiont from an initial condition to a later condition, occurring in its host's vascular tissue. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	growth or development of symbiont in host vascular tissue					This term was made obsolete because it contained a conjunction (or). It has been replaced with the terms 'development of symbiont in host vascular tissue ; GO:0044122' and 'growth of symbiont in host vascular tissue ; GO:0044123'.	GO:0044114|GO:0051701				True			biological_process											owl:Class	
GO:0039582	biolink:NamedThing	obsolete suppression by virus of host PKR activity by positive regulation of PKR nuclear localization	OBSOLETE. Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host PKR (protein kinase regulated by RNA) activity by promoting the localization of PKR in the nucleus. For example, human cytomegalovirus (HMCV) gene products directly interact with PKR and inhibit its activation by sequestering it in the nucleus, away from both its activator (cytoplasmic dsRNA) and its substrate, (eIF2alpha).	tmpzr1t_l9r_go_relaxed.owl	suppression by virus of host PKR activity by sequestering of PKR in nucleus|suppression by virus of host PKR activity by positive regulation of PKR localization to nucleus|suppression by virus of host PKR activity by nuclear sequestration of PKR					The reason for obsoleting this term is that it is too specific. The exact molecular roles of the individual proteins should be captured separately.		bf			True			biological_process											owl:Class	
GO:1904110	biolink:NamedThing	obsolete regulation of plus-end directed microfilament motor activity	OBSOLETE. Any process that modulates the frequency, rate or extent of plus-end directed microfilament motor activity.	tmpzr1t_l9r_go_relaxed.owl	regulation of barbed-end directed actin-filament motor activity|regulation of plus-end directed actin-filament motor activity|regulation of plus-end directed actin filament motor activity	https://github.com/geneontology/go-ontology/issues/21626				This term was obsoleted because it represents a molecular function.	GO:0140659	kmv	2015-04-03T18:28:24Z		True			biological_process											owl:Class	
GO:1904725	biolink:NamedThing	obsolete TFIIB-class transcription factor binding involved in negative regulation of transcription	OBSOLETE. Any TFIIB-class transcription factor binding that is involved in negative regulation of DNA-templated transcription.	tmpzr1t_l9r_go_relaxed.owl	TFIIB-class transcription factor binding involved in negative regulation of gene-specific transcription|TFIIB-class transcription factor binding involved in negative regulation of transcription, DNA-templated|TFIIB-class transcription factor binding involved in downregulation of transcription, DNA-dependent|TFIIB-class transcription factor binding involved in down-regulation of gene-specific transcription|TFIIB-class transcription factor binding involved in inhibition of transcription, DNA-dependent|TFIIB-class transcription factor binding involved in inhibition of gene-specific transcription|TFIIB-class transcription factor binding involved in down regulation of transcription, DNA-dependent|TFIIB-class transcription factor binding involved in negative regulation of cellular transcription, DNA-dependent|TFIIB-class transcription factor binding involved in transcription repressor activity|TFIIB-class transcription factor binding involved in downregulation of gene-specific transcription|TFIIB-class transcription factor binding involved in down regulation of gene-specific transcription|TFIIB-class transcription factor binding involved in negative regulation of transcription, DNA-dependent|TFIIB-class transcription factor binding involved in down-regulation of transcription, DNA-dependent					The reason for obsoletion is that this term represents a GO-CAM model.		tb	2015-10-13T19:49:39Z		True			molecular_function											owl:Class	
GO:0019059	biolink:NamedThing	obsolete initiation of viral infection	OBSOLETE. The set of processes involved in the start of virus infection of cells.	tmpzr1t_l9r_go_relaxed.owl	initiation of viral infection					This term was made obsolete because it is ambiguous, and more specific terms have been created.	GO:0046718				True			biological_process											owl:Class	
GO:0016329	biolink:NamedThing	obsolete apoptosis regulator activity	OBSOLETE. The function held by products which directly regulate any step in the process of apoptosis.	tmpzr1t_l9r_go_relaxed.owl	apoptosis regulator activity			GO:0042981		This term was made obsolete because it represents involvement in a biological process.					True			molecular_function											owl:Class	
GO:0042408	biolink:NamedThing	obsolete myrcene/(E)-beta-ocimene synthase activity	OBSOLETE. Catalysis of the conversion of geranyl diphosphate (GPP) into the acyclic monoterpenes beta-myrcene, (E)-beta-ocimene, and other minor cyclic monoterpenes.	tmpzr1t_l9r_go_relaxed.owl	myrcene/(E)-beta-ocimene synthase activity|myrcene/ocimene synthase activity				EC:4.6.-.-	This term was made obsolete because it represents two activities.					True			molecular_function											owl:Class	
GO:0046024	biolink:NamedThing	obsolete positive regulation of transcription from RNA polymerase III promoter during mitotic cell cycle	OBSOLETE. Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase III that occurs during the mitotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl	stimulation of transcription from RNA polymerase III promoter during mitosis|positive regulation of transcription from Pol III promoter during mitosis|up regulation of transcription from RNA polymerase III promoter during mitosis|positive regulation of transcription from RNA polymerase III promoter, mitotic|activation of transcription from RNA polymerase III promoter during mitosis|mitotic activation of transcription from Pol III promoter|upregulation of transcription from RNA polymerase III promoter during mitosis|up-regulation of transcription from RNA polymerase III promoter during mitosis	https://github.com/geneontology/go-ontology/issues/14896				The reason for obsoletion is that 'during' should be captured using an annotation extension.	GO:0045945|GO:0044772				True			biological_process											owl:Class	
GO:1903079	biolink:NamedThing	obsolete negative regulation of protein localization to cell tip involved in positive regulation of establishment of cell polarity regulating cell shape	OBSOLETE. Any negative regulation of protein localization to cell tip that is involved in positive regulation of establishment of cell polarity regulating cell shape.	tmpzr1t_l9r_go_relaxed.owl	down regulation of protein localisation to cell tip involved in positive regulation of establishment of cell polarity regulating cell shape|down regulation of protein localization to cell tip involved in positive regulation of establishment of cell polarity regulating cell shape|inhibition of protein localisation to cell tip involved in positive regulation of establishment of cell polarity regulating cell shape|downregulation of protein localisation to cell tip involved in positive regulation of establishment of cell polarity regulating cell shape|down-regulation of protein localization to cell tip involved in positive regulation of establishment of cell polarity regulating cell shape|negative regulation of protein localisation to cell tip involved in positive regulation of establishment of cell polarity regulating cell shape|down-regulation of protein localisation to cell tip involved in positive regulation of establishment of cell polarity regulating cell shape|downregulation of protein localization to cell tip involved in positive regulation of establishment of cell polarity regulating cell shape|inhibition of protein localization to cell tip involved in positive regulation of establishment of cell polarity regulating cell shape|negative regulation of protein localization to cell tip involved in positive regulation of establishment of cell polarity regulating cell shape					This term was obsoleted at the TermGenie Gatekeeper stage.		vw	2014-05-29T17:42:24Z		True			biological_process											owl:Class	
GO:1903616	biolink:NamedThing	obsolete MAPK cascade involved in axon regeneration	OBSOLETE. Any MAPK cascade that is involved in axon regeneration.	tmpzr1t_l9r_go_relaxed.owl	MAP kinase kinase kinase cascade involved in axon regeneration|MAPK signalling involved in axon regeneration|MAPKKK cascade involved in axon regeneration|MAPKKK cascade during sporulation involved in axon regeneration|mitogen-activated protein kinase cascade involved in axon regeneration|ERK/MAPK cascade involved in axon regeneration|MAPK signal transduction involved in axon regeneration|MAPK signaling involved in axon regeneration|MAP kinase cascade involved in axon regeneration	https://github.com/geneontology/go-ontology/issues/14323				This term was obsoleted because it represents a GO-CAM model.		kmv	2014-11-18T19:11:59Z		True			biological_process											owl:Class	
GO:0052379	biolink:NamedThing	obsolete modulation by organism of entry into other organism via phagocytosis involved in symbiotic interaction	OBSOLETE. Any process in which an organism modulates the frequency, rate or extent to which it enters into a second organism via the phagocytotic processes of the other organism, where the two organisms are in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	modulation by organism of entry into other organism via phagocytosis during symbiotic interaction|modulation by organism of entry into other organism via other organism phagocytosis during symbiotic interaction	https://github.com/geneontology/go-ontology/issues/18562				This term was obsoleted because there is no evidence that this process exists.					True			biological_process											owl:Class	
GO:0023048	biolink:NamedThing	obsolete signal initiation by lipid mediator	OBSOLETE. The process in which a lipid signal causes activation of a receptor.	tmpzr1t_l9r_go_relaxed.owl	signal initiation by lipid mediator					This term was made obsolete because the meaning of the term is ambiguous.	GO:0045125|GO:0007165		2010-02-16T09:30:50Z		True			biological_process											owl:Class	
GO:0021913	biolink:NamedThing	obsolete regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification	OBSOLETE. Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that results in the commitment of a cell to become an interneuron in the ventral spinal cord.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it represents a GO-CAM model.	GO:0006357|GO:0021521				True			biological_process											owl:Class	
GO:0002198	biolink:NamedThing	obsolete S/G2 transition of mitotic cell cycle	OBSOLETE. The transition from a cell in the S phase to the G2 phase.	tmpzr1t_l9r_go_relaxed.owl	S/G2 transition of mitotic cell cycle					This term was made obsolete because it does not refer to a real biological process.		hjd	2011-11-02T10:36:58Z		True			biological_process											owl:Class	
GO:0007201	biolink:NamedThing	obsolete G-protein dissociation	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	G-protein dissociation					This term was made obsolete because the dissociation of heterotrimeric G protein subunits is a consequence of a conformational change, which is in turn a consequence of ligand binding; it does not require multiple activities specifically to bring about.					True			biological_process											owl:Class	
RO:0002216	biolink:NamedThing	capable of part of		tmpzr1t_l9r_go_relaxed.owl					RO:0002216									external									capable_of_part_of			
GO:0051088	biolink:NamedThing	obsolete PMA-inducible membrane protein ectodomain proteolysis	OBSOLETE. The proteolytic cleavage of transmembrane proteins and release of their ectodomain that occurs after induction by phorbol-12-myristate-13-acetate (PMA), a protein kinase C agonist.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/19855				This term was obsoleted because it represents an assay to induce PKC.					True			biological_process											owl:Class	
GO:1903161	biolink:NamedThing	obsolete pantothenate transmembrane transporter activity involved in pantothenate import into cell	OBSOLETE. Any pantothenate transmembrane transporter activity that is involved in pantothenate import into cell.	tmpzr1t_l9r_go_relaxed.owl	pantothenate transmembrane transporter activity involved in pantothenate import into cell|vitamin B5 transmembrane transporter activity involved in pantothenate import into cell					This term was obsoleted at the TermGenie Gatekeeper stage.		dos	2014-07-09T11:56:38Z		True			molecular_function											owl:Class	
GO:0015484	biolink:NamedThing	obsolete hemolysin activity	OBSOLETE. Any substance that causes the lysis of red blood cells.	tmpzr1t_l9r_go_relaxed.owl	hemolysin activity					This term was made obsolete because it represents a gene product.	GO:0019836				True			molecular_function											owl:Class	
GO:0003762	biolink:NamedThing	obsolete histone-specific chaperone activity	OBSOLETE. Assists in chromatin assembly by chaperoning histones on to replicating DNA, but is not a component of the assembled nucleosome when performing its normal biological function.	tmpzr1t_l9r_go_relaxed.owl	histone-specific chaperone activity|nucleosome assembly chaperone					This term was made obsolete because it represents a class of gene products and a biological process rather than a molecular function.	GO:0034728|GO:0043486|GO:0051082|GO:0042393|GO:0044183|GO:0006333|GO:0006334				True			molecular_function											owl:Class	
GO:0090413	biolink:NamedThing	obsolete negative regulation of transcription from RNA polymerase II promoter involved in fatty acid biosynthetic process	OBSOLETE. Any negative regulation of transcription from RNA polymerase II promoter that is involved in fatty acid biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of transcription from RNA polymerase II promoter involved in fatty acid biosynthetic process						GO:0000122	tb	2011-09-01T03:10:41Z		True			biological_process											owl:Class	
GO:0100019	biolink:NamedThing	obsolete regulation of cAMP-mediated signaling by transcription from RNA polymerase II promoter	OBSOLETE. Any transcription from RNA polymerase II promoter process that regulates cAMP-mediated signaling.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/14279				The reason for obsoletion is that cAMP-mediated signaling is not mediated by transcription from RNA polII promoter.		cjm	2015-04-02T04:13:19Z		True			biological_process											owl:Class	
GO:0005649	biolink:NamedThing	obsolete transportin	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	transportin|karyopherin-beta2					This term was made obsolete because it represents a single gene product and not a complex.	GO:0005634|GO:0005643|GO:0005737				True			cellular_component											owl:Class	
GO:1902886	biolink:NamedThing	obsolete negative regulation of proteasome-activating ATPase activity	OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of proteasome-activating ATPase activity.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of ATPase involved in positive regulation of proteasomal protein catabolic process|negative regulation of proteasome channel opening activity|down regulation of proteasome channel opening activity|down-regulation of proteasome-activating ATPase activity|downregulation of ATPase involved in positive regulation of proteasomal protein catabolic process|downregulation of proteasomal ATPase activity|downregulation of proteasome channel opening activity|down regulation of proteasomal ATPase activity|down-regulation of proteasomal ATPase activity|inhibition of ATPase involved in positive regulation of proteasomal protein catabolic process|down-regulation of proteasome channel opening activity|down-regulation of proteasome channel gating activity|inhibition of proteasomal ATPase activity|down-regulation of ATPase involved in positive regulation of proteasomal protein catabolic process|down regulation of proteasome channel gating activity|downregulation of proteasome channel gating activity|negative regulation of proteasomal ATPase activity|negative regulation of proteasome channel gating activity|downregulation of proteasome-activating ATPase activity|inhibition of proteasome-activating ATPase activity|inhibition of proteasome channel opening activity|inhibition of proteasome channel gating activity|down regulation of proteasome-activating ATPase activity|down regulation of ATPase involved in positive regulation of proteasomal protein catabolic process	https://github.com/geneontology/go-ontology/issues/20879				This term was obsoleted because it represents a molecular function.		di	2014-04-04T17:35:30Z		True			biological_process											owl:Class	
GO:0042969	biolink:NamedThing	obsolete lactone transport	OBSOLETE. The directed movement of lactone from one side of a membrane to the other. A lactone is a cyclic ester of a hydroxy carboxylic acid, containing a 1-oxacycloalkan-2-one structure, or an analogue having unsaturation or heteroatoms replacing one or more carbon atoms of the ring.	tmpzr1t_l9r_go_relaxed.owl						This term aws obsoleted because there is no evidence for a specific pathway to transport lactone.					True			biological_process											owl:Class	
GO:0018328	biolink:NamedThing	obsolete enzyme active site formation via 3'-phospho-L-histidine	OBSOLETE. The transient phosphorylation of peptidyl-histidine to form 3'-phospho-L-histidine (otherwise known as pi-phosphohistidine, pros-phosphohistidine).	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/15594			RESID:AA0036	This term was obsoleted because it represents a reaction intermediate, not a biological process, see PMID:11168390.	GO:0008256				True			biological_process											owl:Class	
GO:0045885	biolink:NamedThing	obsolete positive regulation of survival gene product expression	OBSOLETE. Any process that activates or increases the frequency, rate or extent of survival gene product expression; survival gene products are those that antagonize the apoptotic program. Regulation can be at the transcriptional, translational, or posttranslational level.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of survival gene product activity|activation of survival gene product activity|upregulation of survival gene product activity|positive regulation of survival gene product expression|stimulation of survival gene product activity|up-regulation of survival gene product activity|positive regulation of survival gene products|up regulation of survival gene product activity					This term was made obsolete because the meaning of the term is ambiguous: the same gene product may or may not have a role in apoptosis depending on the cell type, tissue type, condition, etc.					True			biological_process											owl:Class	
GO:0016975	biolink:NamedThing	obsolete alpha-2 macroglobulin	OBSOLETE. Inhibition of proteinase by a mechanism involving a bait region which contains specific sites, cleavage of which induces a conformational change that results in trapping of the proteinase; following cleavage in the bait region a thiolester bond is hydrolyzed and mediates the covalent binding of the protein to the proteinase; subsequently epsilon-amino groups of the proteinase react with thiolester linkages in the inhibitor to form stable amide links; the entrapped proteinase can now only act on low molecular mass substrates.	tmpzr1t_l9r_go_relaxed.owl	alpha-2 macroglobulin			GO:0004866		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0007592	biolink:NamedThing	obsolete protein-based cuticle development	OBSOLETE. Synthesis and deposition of a protein-based noncellular, hardened, or membranous secretion from an epithelial sheet. An example of this is found in Caenorhabditis elegans.	tmpzr1t_l9r_go_relaxed.owl	protein-based cuticle formation|protein-based cuticle anabolism|protein-based cuticle development|protein-based cuticle biosynthetic process|protein-based cuticle synthesis					This term was made obsolete because 'protein-based cuticle' is an unnecessary grouping term.	GO:0040002|GO:0040003				True			biological_process											owl:Class	
GO:1904920	biolink:NamedThing	obsolete regulation of MAPK cascade involved in axon regeneration	OBSOLETE. Any process that modulates the frequency, rate or extent of MAPK cascade involved in axon regeneration.	tmpzr1t_l9r_go_relaxed.owl	regulation of MAP kinase kinase kinase cascade involved in axon regeneration|regulation of mitogen-activated protein kinase cascade involved in axon regeneration|regulation of ERK/MAPK cascade involved in axon regeneration|regulation of MAP kinase cascade involved in axon regeneration|regulation of MAPKKK cascade involved in axon regeneration|regulation of MAPKKK cascade during sporulation involved in axon regeneration|regulation of MAPK signal transduction involved in axon regeneration|regulation of MAPK signaling involved in axon regeneration|regulation of MAPK signalling involved in axon regeneration	https://github.com/geneontology/go-ontology/issues/14323				This term was obsoleted because it represents a GO-CAM model.		kmv	2016-01-25T17:03:35Z		True			biological_process											owl:Class	
GO:0006372	biolink:NamedThing	obsolete lariat formation, 5'-splice site cleavage	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	lariat formation, 5'-splice site cleavage					This term was made obsolete because it represents a molecular function.	GO:0000386|GO:0000350				True			biological_process											owl:Class	
GO:0007251	biolink:NamedThing	obsolete activation of the inhibitor of kappa kinase	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	activation of the inhibitor of kappa kinase					This term was made obsolete because its meaning was unclear.	GO:0007249				True			biological_process											owl:Class	
GO:0046017	biolink:NamedThing	obsolete regulation of transcription from RNA polymerase I promoter during mitotic cell cycle	OBSOLETE. A cell cycle process that modulates the frequency, rate or extent of transcription from an RNA polymerase I promoter that occurs during the mitotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl	regulation of transcription from Pol I promoter during mitosis|regulation of transcription from RNA polymerase I promoter during mitosis|mitotic regulation of transcription from Pol I promoter	https://github.com/geneontology/go-ontology/issues/14896				The reason for obsoletion is that 'during' should be captured using an annotation extension.	GO:0044772|GO:0006356				True			biological_process											owl:Class	
GO:0009465	biolink:NamedThing	obsolete soluble cytochrome b562	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	soluble cytochrome b562			GO:0004129		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0090019	biolink:NamedThing	obsolete regulation of transcription involved in anterior neural plate formation	OBSOLETE. Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter contributing to the formation of the anterior neural plate.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it represents a GO-CAM model.	GO:0090017|GO:0006357	tb	2009-07-29T11:38:28Z		True			biological_process											owl:Class	
GO:0018853	biolink:NamedThing	obsolete perillyl-CoA synthetase activity	OBSOLETE. Catalysis of the reaction: perillic acid + CoA-SH + ATP = H2O + ADP/AMP + mono/diphosphate + perillyl-CoA.	tmpzr1t_l9r_go_relaxed.owl	perillyl-CoA synthetase activity				UM-BBD_reactionID:r0731|EC:6.2.1.-	This term was made obsolete because it represents two reactions.	GO:0052685|GO:0052686				True			molecular_function											owl:Class	
GO:0075515	biolink:NamedThing	obsolete viral entry into host cell via caveolin-mediated endocytosis followed by genetic injection through the endosome membrane	OBSOLETE. The uptake of a virus into a host cell that begins when material is taken up into plasma membrane caveolae which then pinch off to form endocytic caveolar carriers containing the virus. The caveolar carriers then deliver their viral content to early endosomes, and the process ends when viral nucleic acid is released into the host cytoplasm by its injection through the endosome membrane.	tmpzr1t_l9r_go_relaxed.owl	viral entry into host cell via caveolae-mediated endocytosis followed by genetic injection through the endosome membrane|viral entry into host cell via caveolin-mediated endocytosis followed by genetic injection through the endosome membrane					This term was made obsolete because it doesn't represent a genuine process. The term injection is mostly used for prokaryotic viruses where there is no endocytosis.		jl	2011-07-27T02:57:55Z		True			biological_process											owl:Class	
GO:1900435	biolink:NamedThing	obsolete negative regulation of filamentous growth of a population of unicellular organisms in response to starvation	OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to starvation.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of filamentous growth of a population of unicellular organisms in response to starvation|inhibition of filamentous growth of a population of unicellular organisms in response to starvation|down regulation of filamentous growth of a population of unicellular organisms in response to starvation|downregulation of filamentous growth of a population of unicellular organisms in response to starvation					This term was obsoleted because it represents a GO-CAM model.		di	2012-04-25T05:54:56Z		True			biological_process											owl:Class	
GO:0046299	biolink:NamedThing	obsolete 2,4-dichlorophenoxyacetic acid biosynthetic process	OBSOLETE. The chemical reactions and pathways resulting in the formation of 2,4-dichlorophenoxyacetic acid, a chlorinated phenoxy compound which functions as a systemic herbicide and is used to control many types of broadleaf weeds.	tmpzr1t_l9r_go_relaxed.owl	2,4-dichlorophenoxyacetic acid anabolism|2,4-dichlorophenoxyacetic acid biosynthetic process|2,4-dichlorophenoxyacetic acid biosynthesis|2,4-dichlorophenoxyacetic acid synthesis|2,4-dichlorophenoxyacetic acid formation			GO:0018901		This term was made obsolete because 2,4-dichlorophenoxyacetic acid is not synthesized by living organisms and GO does not cover non-biological processes.					True			biological_process											owl:Class	
GO:0001628	biolink:NamedThing	obsolete gastropyloric receptor activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	GPR receptor|gastropyloric receptor activity					This term was made obsolete because the gastropyloric receptor is a type of neuron.					True			molecular_function											owl:Class	
GO:0075166	biolink:NamedThing	obsolete positive regulation of G-protein gamma subunit-mediated signal transduction in response to host	OBSOLETE. Any process in which the symbiont organism activates, maintains or increases the frequency, rate or extent of its G-protein gamma subunit-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of symbiont G-protein gamma subunit-mediated signal transduction in response to host					This term was obsoleted because there is no evidence that this process exists.					True			biological_process											owl:Class	
GO:0001153	biolink:NamedThing	obsolete transcription factor activity, RNA polymerase III transcription factor recruiting	OBSOLETE. The function of binding to an RNA polymerase III (RNAP III) transcription factor and recruiting it to the transcription machinery complex in order to modulate transcription by RNAP III.	tmpzr1t_l9r_go_relaxed.owl	RNA polymerase III transcription factor recruiting transcription factor activity					This term was made obsolete in the 2018 Transcription branch revision. This term was redundant with other terms.		krc	2011-01-27T04:45:37Z		True			molecular_function											owl:Class	
GO:1990639	biolink:NamedThing	obsolete inositol-3,4,5-trisphosphate 5-phosphatase activity	OBSOLETE. Catalysis of the reaction: D-myo-inositol 3,4,5-trisphosphate + H2O = myo-inositol 3,4-bisphosphate + phosphate.	tmpzr1t_l9r_go_relaxed.owl	inositol-3,4,5-trisphosphate 5-phosphatase activity					This term was obsoleted at the TermGenie Gatekeeper stage.		al	2015-02-11T15:58:56Z		True			molecular_function											owl:Class	
GO:0005573	biolink:NamedThing	obsolete telomerase RNA	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	telomerase RNA			GO:0000332		This term was made obsolete because it represents a gene product.					True			cellular_component											owl:Class	
GO:0004728	biolink:NamedThing	obsolete signal transducer, downstream of receptor, with protein tyrosine phosphatase activity	OBSOLETE. Conveys a signal from an upstream receptor or intracellular signal transducer by catalysis of the reaction: protein tyrosine phosphate + H2O = protein tyrosine + phosphate.	tmpzr1t_l9r_go_relaxed.owl	receptor signalling protein tyrosine phosphatase activity|receptor signaling protein tyrosine phosphatase activity	https://github.com/geneontology/go-ontology/issues/14232				This term was obsoleted because it was not clearly defined.					True			molecular_function											owl:Class	
GO:2001220	biolink:NamedThing	obsolete negative regulation of G2 phase of mitotic cell cycle	OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of G2 phase of mitotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of G2 phase of mitotic cell cycle					This term was made obsolete because it does not refer to a real biological process.		yaf	2011-11-17T03:28:44Z		True			biological_process											owl:Class	
GO:1900546	biolink:NamedThing	obsolete positive regulation of phenotypic switching by regulation of transcription from RNA polymerase II promoter	OBSOLETE. A regulation of transcription from RNA polymerase II promoter that results in positive regulation of phenotypic switching.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of phenotypic dimorphism by regulation of transcription from RNA polymerase II promoter|up regulation of phenotypic switching by regulation of transcription from RNA polymerase II promoter|positive regulation of phenotypic dimorphism by regulation of transcription from RNA polymerase II promoter|upregulation of phenotypic switching by regulation of transcription from RNA polymerase II promoter|upregulation of phenotypic dimorphism by regulation of transcription from RNA polymerase II promoter|up regulation of phenotypic dimorphism by regulation of transcription from RNA polymerase II promoter|activation of phenotypic switching by regulation of transcription from RNA polymerase II promoter|up-regulation of phenotypic switching by regulation of transcription from RNA polymerase II promoter|activation of phenotypic dimorphism by regulation of transcription from RNA polymerase II promoter					This term was obsoleted because it represents a GO-CAM model.		di	2012-05-14T11:36:05Z		True			biological_process											owl:Class	
GO:0075154	biolink:NamedThing	obsolete positive regulation of transmembrane receptor-mediated signal transduction in response to host	OBSOLETE. Any process in which the symbiont organism activates, maintains or increases the frequency, rate or extent of its transmembrane receptor-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because there is no evidence that this process exists.					True			biological_process											owl:Class	
GO:0030181	biolink:NamedThing	obsolete sodium:calcium exchange	OBSOLETE. Exchange diffusion sodium and calcium ions in which influx of sodium ions to the cytosol drives the efflux of calcium ions from the cell.	tmpzr1t_l9r_go_relaxed.owl	sodium:calcium exchange					This term was made obsolete because it represents a function rather than a process.	GO:0006814|GO:0005432|GO:0006816				True			biological_process											owl:Class	
GO:0004291	biolink:NamedThing	obsolete subtilisin activity	OBSOLETE. Catalysis of the hydrolysis of proteins with broad specificity for peptide bonds, and a preference for a large uncharged residue in P1. Hydrolyzes peptide amides.	tmpzr1t_l9r_go_relaxed.owl	subtilisin S41|bioprase AL 15|subtilisin E|savinase activity|bacillopeptidase A|thermoase PC 10|savinase 4.0T|maxatase activity|protease S|ALK-enzyme|bacillus subtilis alkaline proteinase activity|protease VIII|savinase 16.0L|bacillus subtilis alkaline proteinase bioprase activity|esperase activity|SP 266|subtilopeptidase activity|subtilisin activity|savinase 32.0 L EX|subtilisin DY|savinase 8.0L|thermoase|protin A 3L|kazusase activity|alcalase 2.5L|orientase 10B|opticlean|genenase I|bacillopeptidase B|protease XXVII|subtilisin BL|bioprase APL 30|alcalase activity|superase activity|subtilisin sendai|colistinase activity|subtilisin GX|alcalase 0.6L|subtilisin J			GO:0004252		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0017106	biolink:NamedThing	obsolete activin inhibitor activity	OBSOLETE. Acts to negatively regulate the activity of activin, a nonsteroidal regulator synthesized in the pituitary gland and gonads that stimulates the secretion of follicle-stimulating hormone.	tmpzr1t_l9r_go_relaxed.owl	activin inhibitor activity					This term was made obsolete because it refers to an obsolete molecular function term, 'activin'.	GO:0098772				True			molecular_function											owl:Class	
GO:0052530	biolink:NamedThing	obsolete positive regulation by organism of symbiont resistance gene-dependent defense response	OBSOLETE. Any process by which an organism activates, maintains or increases the frequency, rate or extent of the resistance gene-dependent defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	positive regulation by organism of defense response in symbiont by specific elicitors|positive regulation by organism of symbiont resistance gene-dependent defense response|positive regulation by organism of symbiont gene-for-gene resistance|positive regulation by organism of pathogen-race/symbiont plant cultivar-specific resistance in symbiont					This term was made obsolete because it does not represent a real biological process.					True			biological_process											owl:Class	
GO:0004294	biolink:NamedThing	obsolete tripeptidyl-peptidase II activity	OBSOLETE. Catalysis of the release of an N-terminal tripeptide from a polypeptide at neutral pH.	tmpzr1t_l9r_go_relaxed.owl	tripeptidyl aminopeptidase II|tripeptidyl peptidase II|tripeptidyl-peptidase II activity|TPP|tripeptidyl peptidase activity|tripeptidyl aminopeptidase activity			GO:0008240		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0071428	biolink:NamedThing	obsolete rRNA-containing ribonucleoprotein complex export from nucleus	OBSOLETE. The directed movement of a ribonucleoprotein complex that contains ribosomal RNA from the nucleus to the cytoplasm.	tmpzr1t_l9r_go_relaxed.owl	rRNA-containing ribonucleoprotein complex export from cell nucleus|rRNA-containing ribonucleoprotein complex nucleus export|rRNA-containing ribonucleoprotein complex transport from nucleus to cytoplasm|rRNA-containing RNP export from nucleus	https://github.com/geneontology/go-ontology/issues/22246				This term has been obsoleted because it represents the transport of a carrier bound to its substrate.		mah	2009-12-16T10:15:07Z		True			biological_process											owl:Class	
GO:2000580	biolink:NamedThing	obsolete regulation of microtubule motor activity, plus-end-directed	OBSOLETE. Any process that modulates the frequency, rate or extent of ATP-dependent microtubule motor activity, plus-end-directed.	tmpzr1t_l9r_go_relaxed.owl	regulation of plus-end-directed kinesin ATPase activity|regulation of kinesin activity|regulation of ATP-dependent microtubule motor activity, plus-end-directed|regulation of kinesin ATP phosphohydrolase (plus-end-directed)|regulation of plus-end-directed microtubule motor activity	https://github.com/geneontology/go-ontology/issues/21626				This term was obsoleted because it represents a molecular function.	GO:0140659	bf	2011-04-05T08:39:43Z		True			biological_process											owl:Class	
GO:0007247	biolink:NamedThing	obsolete activation of MAPK (mating sensu Saccharomyces)	OBSOLETE. Upregulation of MAP kinase activity in the context of transduction of mating pheromone signal, as described for Saccharomyces.	tmpzr1t_l9r_go_relaxed.owl	activation of MAPK (mating sensu Saccharomyces)					This term was made obsolete because it is a gene product specific term.	GO:0000750				True			biological_process											owl:Class	
GO:0031378	biolink:NamedThing	obsolete plastid type II fatty acid synthase complex	OBSOLETE. A fatty acid synthase complex in which each polypeptide chain catalyzes a single activity, located in a plastid.	tmpzr1t_l9r_go_relaxed.owl	plastid type II fatty acid synthase complex|plastid type II FAS complex					Obsoleted because type II fatty acid synthase is not a complex.					True			cellular_component											owl:Class	
GO:0048184	biolink:NamedThing	obsolete follistatin binding	OBSOLETE. Binding to the peptide hormone follistatin.	tmpzr1t_l9r_go_relaxed.owl	follistatin binding			GO:0017046		This term was made obsolete because it represents binding to an individual protein.					True			molecular_function											owl:Class	
GO:0003102	biolink:NamedThing	obsolete positive regulation of diuresis by angiotensin	OBSOLETE. Any process mediated by angiotensin that increases the rate of diuresis.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of diuresis by angiotensin|angiotensin-mediated positive regulation of diuresis					This term was made obsolete because the term is misleading.	GO:0035810				True			biological_process											owl:Class	
GO:0052326	biolink:NamedThing	obsolete interaction with symbiont via protein secreted by type IV secretion system	OBSOLETE. An interaction with the symbiont organism mediated by a substance secreted by the other organism by a type IV secretion system. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	interaction with symbiont via protein secreted by type IV secretion system					This term was made obsolete because it does not represent a real biological process.					True			biological_process											owl:Class	
GO:0021865	biolink:NamedThing	obsolete symmetric radial glial cell division in forebrain	OBSOLETE. The mitotic division of a radial glial cell giving rise to two new radial glial cells in the forebrain.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it represents a GO-CAM model.					True			biological_process											owl:Class	
GO:0052205	biolink:NamedThing	obsolete modulation of molecular function in other organism involved in symbiotic interaction	OBSOLETE. The process in which an organism effects a change in the function of proteins in a second organism, where the two organisms are in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	modulation of molecular function in other organism during symbiotic interaction|modification of protein function in other organism during symbiotic interaction|modification of molecular function in other organism during symbiotic interaction					This term was obsoleted because it represents an unnecessary grouping class.					True			biological_process											owl:Class	
GO:0015596	biolink:NamedThing	obsolete glycine betaine/proline porter activity	OBSOLETE. Catalysis of the reaction: ATP + H2O + quaternary amine(out) = ADP + phosphate + quaternary amine(in).	tmpzr1t_l9r_go_relaxed.owl	glycine betaine/proline porter activity					This term was made obsolete because it represents a multifunctional gene product.	GO:0015187|GO:0015418|GO:0015193|GO:0015199				True			molecular_function											owl:Class	
GO:0009467	biolink:NamedThing	obsolete monoheme class I cytochrome c	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	monoheme class I cytochrome c					This term was made obsolete because it represents a gene product.	GO:0009055				True			molecular_function											owl:Class	
GO:0042499	biolink:NamedThing	obsolete signal peptide peptidase activity	OBSOLETE. Catalysis of the intramembrane proteolysis of a signal peptide, following its removal from a preprotein.	tmpzr1t_l9r_go_relaxed.owl	signal peptide peptidase activity|SPP			GO:0042500		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:1900418	biolink:NamedThing	obsolete positive regulation of purine nucleotide biosynthetic process by positive regulation of transcription from RNA polymerase II promoter	OBSOLETE. A positive regulation of transcription from RNA polymerase II promoter that results in positive regulation of purine nucleotide biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	activation of purine nucleotide biosynthetic process by positive regulation of transcription from RNA polymerase II promoter|positive regulation of purine nucleotide formation by positive regulation of transcription from RNA polymerase II promoter|upregulation of purine nucleotide biosynthesis by positive regulation of transcription from RNA polymerase II promoter|up-regulation of purine nucleotide biosynthesis by positive regulation of transcription from RNA polymerase II promoter|up-regulation of purine nucleotide formation by positive regulation of transcription from RNA polymerase II promoter|up regulation of purine nucleotide biosynthetic process by positive regulation of transcription from RNA polymerase II promoter|upregulation of purine nucleotide synthesis by positive regulation of transcription from RNA polymerase II promoter|up regulation of purine nucleotide formation by positive regulation of transcription from RNA polymerase II promoter|upregulation of purine nucleotide formation by positive regulation of transcription from RNA polymerase II promoter|up regulation of purine nucleotide biosynthesis by positive regulation of transcription from RNA polymerase II promoter|positive regulation of purine nucleotide synthesis by positive regulation of transcription from RNA polymerase II promoter|activation of purine nucleotide biosynthesis by positive regulation of transcription from RNA polymerase II promoter|upregulation of purine nucleotide anabolism by positive regulation of transcription from RNA polymerase II promoter|upregulation of purine nucleotide biosynthetic process by positive regulation of transcription from RNA polymerase II promoter|positive regulation of purine nucleotide anabolism by positive regulation of transcription from RNA polymerase II promoter|up-regulation of purine nucleotide biosynthetic process by positive regulation of transcription from RNA polymerase II promoter|activation of purine nucleotide anabolism by positive regulation of transcription from RNA polymerase II promoter|up regulation of purine nucleotide anabolism by positive regulation of transcription from RNA polymerase II promoter|positive regulation of purine nucleotide biosynthesis by positive regulation of transcription from RNA polymerase II promoter|up-regulation of purine nucleotide synthesis by positive regulation of transcription from RNA polymerase II promoter|activation of purine nucleotide synthesis by positive regulation of transcription from RNA polymerase II promoter|activation of purine nucleotide formation by positive regulation of transcription from RNA polymerase II promoter|up-regulation of purine nucleotide anabolism by positive regulation of transcription from RNA polymerase II promoter|up regulation of purine nucleotide synthesis by positive regulation of transcription from RNA polymerase II promoter					This term was obsoleted because it represents a GO-CAM model.		krc	2012-04-20T10:13:58Z		True			biological_process											owl:Class	
GO:0046410	biolink:NamedThing	obsolete 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase activity	OBSOLETE. Catalysis of the reaction: 2-oxoglutarate + isochorismate = 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate + pyruvate + CO2.	tmpzr1t_l9r_go_relaxed.owl	2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase activity					This term was made obsolete because it was derived from an EC entry (EC:2.5.1.64) that has since been split into two entries.	GO:0070204|GO:0070205				True			molecular_function											owl:Class	
GO:0015034	biolink:NamedThing	obsolete cytochrome P450 activity	OBSOLETE. A cytochrome b-like protein that has a sulfur atom ligated to the iron of the prosthetic group (heme-thiolate); enzymes: typically monooxygenases acting on, typically, lipophilic substrates. The characteristic mode of action of these enzymes is not electron transfer (some P450 enzymes probably do not even involve the reversible Fe(II)/Fe(III) equilibrium), but rather oxygen atom transfer.	tmpzr1t_l9r_go_relaxed.owl	cytochrome P450 activity					This term was made obsolete because it is a grouping term representing a set of gene products.	GO:0019825				True			molecular_function											owl:Class	
GO:0019131	biolink:NamedThing	obsolete tripeptidyl-peptidase I activity	OBSOLETE. Catalysis of the release of an N-terminal tripeptide from a polypeptide; requires acid pH.	tmpzr1t_l9r_go_relaxed.owl	tripeptidyl peptidase activity|tripeptidyl-peptidase I activity|tripeptidyl aminopeptidase activity			GO:0008240		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0009488	biolink:NamedThing	obsolete amicyanin	OBSOLETE. A copper-containing protein that acts as an electron carrier between methylamine dehydrogenase and cytochrome c.	tmpzr1t_l9r_go_relaxed.owl	amicyanin			GO:0009055		This term was made obsolete because it does not represent a molecular function.					True			molecular_function											owl:Class	
GO:0050983	biolink:NamedThing	obsolete deoxyhypusine biosynthetic process from spermidine	OBSOLETE. The chemical reactions resulting in the formation of deoxyhypusine from spermidine by the enzyme [eIF-5A]-deoxyhypusine synthase. The reaction occurs in four steps: 1. spermidine + NAD+ = dehydrospermidine + NADH + H+; 2. dehydrospermidine + [enzyme]-lysine = 1,3-diaminopropane + [enzyme]-lysine-N6=CH(CH2)3NH2; 3. [enzyme]-lysine-N6=CH(CH2)3NH2 = [eIF-5A]-lysine-N6=CH(CH2)3NH2; 4. [eIF-5A]-lysine-N6=CH(CH2)3NH2 + NADH + H+ = [eIF-5A]-deoxyhypusine + NAD+.	tmpzr1t_l9r_go_relaxed.owl	[eIF-5A]-deoxyhypusine synthase activity|deoxyhypusine biosynthesis from spermidine, using deoxyhypusine synthase|deoxyhypusine biosynthetic process from spermidine, using deoxyhypusine synthase|deoxyhypusine anabolism from spermidine, using deoxyhypusine synthase|spermidine catabolic process to deoxyhypusine, using deoxyhypusine synthase|(4-aminobutyl)lysine synthase activity|spermidine breakdown to deoxyhypusine, using deoxyhypusine synthase|deoxyhypusine formation from spermidine, using deoxyhypusine synthase|spermidine degradation to deoxyhypusine, using deoxyhypusine synthase				MetaCyc:2.5.1.46-RXN|EC:2.5.1.46	The reason for obsoletion is that although GO:0050983 is described as a multistep process, the entire reaction is carried out by a single enzyme, therefore we would define it as the molecular function GO:0034038 deoxyhypusine synthase activity.	GO:0034038				True			biological_process											owl:Class	
GO:0005240	biolink:NamedThing	obsolete glycine receptor-associated protein	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	glycine receptor-associated protein					This term was made obsolete because it does not describe a molecular function.	GO:0005515				True			molecular_function											owl:Class	
GO:0046243	biolink:NamedThing	obsolete p-xylene biosynthetic process	OBSOLETE. The chemical reactions and pathways resulting in the formation of p-xylene (1,4-dimethylbenzene), a colorless, liquid aromatic hydrocarbon.	tmpzr1t_l9r_go_relaxed.owl	para-xylene biosynthetic process|p-xylene biosynthesis|p-xylene anabolism|para-xylene biosynthesis|p-xylene biosynthetic process|p-xylene formation|p-xylene synthesis			GO:0018951		This term was made obsolete because p-xylene is not synthesized by living organisms, and GO does not cover non-biological processes.					True			biological_process											owl:Class	
GO:0075084	biolink:NamedThing	obsolete modulation by host of symbiont transmembrane receptor-mediated cAMP signal transduction	OBSOLETE. Any process in which the host organism modulates the frequency, rate or extent of transmembrane receptor-mediated cAMP signal transduction in the symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	modulation by host of symbiont transmembrane receptor-mediated cAMP signaling					The reason for obsoletion is that there is no evidence that the host can modulate or regulate a symbiont's signal transduction pathway.					True			biological_process											owl:Class	
GO:0004238	biolink:NamedThing	obsolete meprin A activity	OBSOLETE. Catalysis of the hydrolysis of protein and peptide substrates preferentially on carboxyl side of hydrophobic residues.	tmpzr1t_l9r_go_relaxed.owl	PABA-peptide hydrolase activity|meprin-a|meprin A activity|PPH|meprin|N-benzoyl-L-tyrosyl-p-aminobenzoic acid hydrolase activity|endopeptidase-2 activity			GO:0004222		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0010860	biolink:NamedThing	obsolete proteasome regulator activity	OBSOLETE. Modulates the activity of the proteasome complex. The proteasome complex performs regulated ubiquitin-dependent cytosolic and nuclear proteolysis.	tmpzr1t_l9r_go_relaxed.owl	proteasome regulator activity					The term was made obsolete because 'proteasome' is not a valid molecular function term.	GO:0061135|GO:0061136				True			molecular_function											owl:Class	
GO:0046245	biolink:NamedThing	obsolete styrene biosynthetic process	OBSOLETE. The chemical reactions and pathways resulting in the formation of styrene, an aromatic hydrocarbon liquid used in the manufacture of polystyrene.	tmpzr1t_l9r_go_relaxed.owl	styrene biosynthetic process|styrene biosynthesis|styrene anabolism|styrene formation|styrene synthesis			GO:0018966		This term was made obsolete because styrene is not synthesized by living organisms and GO does not cover non-biological processes.					True			biological_process											owl:Class	
GO:0036226	biolink:NamedThing	obsolete mitotic cell cycle arrest in response to glucose starvation	OBSOLETE. The process in which the mitotic cell cycle is halted during one of the normal phases (G1, S, G2, M) as a result of deprivation of glucose.	tmpzr1t_l9r_go_relaxed.owl	cell cycle arrest in response to glucose starvation					This term was made obsolete because it is superfluous, as only the more specific 'mitotic G2 cell cycle arrest in response to glucose starvation' has been observed.		bf	2012-05-09T02:43:22Z		True			biological_process											owl:Class	
GO:0046143	biolink:NamedThing	obsolete positive regulation of coenzyme and prosthetic group metabolic process	OBSOLETE. Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving coenzymes and prosthetic groups.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of coenzyme and prosthetic group metabolic process					This term was made obsolete because it was replaced by more specific terms.	GO:0051200				True			biological_process											owl:Class	
GO:0015372	biolink:NamedThing	obsolete glutamate/aspartate:sodium symporter activity	OBSOLETE. Catalysis of the reaction: (glutamate or aspartate)(out) + Na+(out) = (glutamate or aspartate)(in) + Na+(in).	tmpzr1t_l9r_go_relaxed.owl	glutamate/aspartate:sodium symporter activity					This term was made obsolete because it represents a multifunctional gene product.	GO:0005313|GO:0005283|GO:0015183				True			molecular_function											owl:Class	
GO:0034019	biolink:NamedThing	obsolete capsanthin/capsorubin synthase activity	OBSOLETE. Catalysis of the reactions: violaxanthin = capsorubin, and antheraxanthin = capsanthin.	tmpzr1t_l9r_go_relaxed.owl	ketoxanthophyll synthase activity|CCS|violaxanthin-capsorubin isomerase (ketone-forming) activity|capsanthin/capsorubin synthase activity|capsanthin-capsorubin synthase activity					This term was made obsolete because it represents two reactions, and should be two separate terms.	GO:0052727|GO:0052728				True			molecular_function											owl:Class	
GO:0018300	biolink:NamedThing	obsolete iron incorporation into iron-sulfur cluster via hexakis-L-cysteinyl hexairon hexasulfide	OBSOLETE. The incorporation of iron into a 6Fe-6S cluster by hexakis-L-cysteinyl hexairon hexasulfide.	tmpzr1t_l9r_go_relaxed.owl	iron incorporation into iron-sulfur cluster via hexakis-L-cysteinyl hexairon hexasulfide|iron incorporation into iron-sulphur cluster via hexakis-L-cysteinyl hexairon hexasulphide					This term was made obsolete because the prismane 6Fe-6S cluster is now thought not to exist.	GO:0018283|GO:0018198				True			biological_process											owl:Class	
GO:0005188	biolink:NamedThing	obsolete larval serum protein (sensu Insecta)	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	larval serum protein (sensu Insecta)|arylphorin					This term was made obsolete because it describes presence in body fluids rather than an activity.					True			molecular_function											owl:Class	
GO:2000327	biolink:NamedThing	obsolete positive regulation of nuclear receptor transcription coactivator activity	OBSOLETE. Any process that activates or increases the frequency, rate or extent of ligand-dependent nuclear receptor transcription coactivator activity.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of ligand-dependent nuclear receptor transcription coactivator activity|positive regulation of ligand-dependent nuclear receptor transcription co-activator activity					This term was obsoleted because it represents a molecular function.	GO:0030374	vk	2011-01-18T06:30:23Z		True			biological_process											owl:Class	
GO:0021909	biolink:NamedThing	obsolete regulation of transcription from RNA polymerase II promoter involved in spinal cord anterior-posterior patterning	OBSOLETE. Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that results in the spatial identity of regions along the anterior-posterior axis of the spinal cord.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it represents a GO-CAM model.	GO:0021512|GO:0006357				True			biological_process											owl:Class	
GO:0016467	biolink:NamedThing	obsolete hydrogen-translocating F-type ATPase activity	OBSOLETE. Catalysis of the reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out). Found in eukaryotic mitochondria and chloroplasts and in bacteria.	tmpzr1t_l9r_go_relaxed.owl	proton-translocating F-type ATPase activity|ATP synthase|hydrogen-translocating F-type ATPase activity|F1-ATPase activity					This term was made obsolete because it represents a gene product.	GO:0046933|GO:0046961				True			molecular_function											owl:Class	
GO:0039551	biolink:NamedThing	obsolete suppression by virus of host IRF3 activity by positive regulation of IRF3 catabolic process	OBSOLETE. Any process in which a virus stops, prevents, or reduces the activity of host IRF3 (interferon regulatory factor-3) by promoting the ubiquitin-dependent degradation of IRF3, mediated by the proteasome.	tmpzr1t_l9r_go_relaxed.owl	promotion by virus of proteosome-dependent IRF3 degradation					The reason for obsoleting this term is that it is too specific. The exact molecular roles of the individual proteins should be captured separately.		bf	2012-01-20T11:35:33Z		True			biological_process											owl:Class	
GO:0051671	biolink:NamedThing	obsolete induction of autolysin activity in other organism	OBSOLETE. Any process in which an organism initiates the activity of the inactive enzyme autolysin in another organism. The autolysin enzyme belongs to, and is active in, the other organism.	tmpzr1t_l9r_go_relaxed.owl	induction of autolysin activity in another organism|positive regulation of autolysin activity in another organism|activation of autolytic activity in other organism|induction of autolytic activity in other organism|induction of autolysis in other organism|activation of autolysin activity in another organism|activation of autolysis in other organism	https://github.com/geneontology/go-ontology/issues/21740				This term was obsoleted because it represents a molecular function.					True			biological_process											owl:Class	
GO:0004290	biolink:NamedThing	obsolete kexin activity	OBSOLETE. Catalysis of the cleavage of the Arg-Xaa bond in Lys-Arg-Xaa and Arg-Arg-Xaa to process Yeast alpha-factor pheromone and killer toxin precursors.	tmpzr1t_l9r_go_relaxed.owl	Kex2-like endoproteinase|protease KEX2|Kex2 endoprotease|endoproteinase Kex2p|paired-basic endopeptidase activity|andrenorphin-Gly-generating enzyme|yeast cysteine proteinase F|kexin activity|Kex2 protease|prohormone-processing proteinase activity|Kex2 endopeptidase|Kex2-like precursor protein processing endoprotease|Kex2 proteinase|proteinase yscF activity|Kex2 endoproteinase|proteinase Kex2p|prohormone-processing endoprotease activity|yeast KEX2 protease activity|prohormone-processing KEX2 proteinase|gene KEX2 dibasic proteinase|Kex 2p proteinase			GO:0004252		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0000193	biolink:NamedThing	obsolete activation of MAPK (pseudohyphal growth)	OBSOLETE. Upregulation of MAP kinase activity in the context of regulating pseudohyphal or invasive growth.	tmpzr1t_l9r_go_relaxed.owl	activation of MAPK (pseudohyphal growth)					This term was made obsolete because it is a gene product specific term.					True			biological_process											owl:Class	
GO:0033171	biolink:NamedThing	obsolete nucleoprotein filament-forming ATPase activity	OBSOLETE. Catalysis of the reaction: ATP + H2O = ADP + phosphate to drive the assembly of proteins such as Rad51p onto single-stranded (ss) DNA to form a helical nucleoprotein filament.	tmpzr1t_l9r_go_relaxed.owl	nucleoprotein filament-forming ATPase activity					This term was made obsolete because nucleoprotein filament formation does not require ATP hydrolysis, so the term is misleading.					True			molecular_function											owl:Class	
GO:1900009	biolink:NamedThing	obsolete positive regulation of extrachromosomal rDNA circle accumulation involved in replicative cell aging	OBSOLETE. Any process that activates or increases the frequency, rate or extent of extrachromosomal rDNA circle accumulation involved in replicative cell aging.	tmpzr1t_l9r_go_relaxed.owl	up regulation of extrachromosomal rDNA circle accumulation during replicative cell ageing|positive regulation of extrachromosomal rDNA circle accumulation during replicative cell ageing|up regulation of extrachromosomal ribosomal DNA circle accumulation during replicative cell aging|up regulation of extrachromosomal rDNA circle accumulation during replicative cell aging|positive regulation of extrachromosomal ribosomal DNA circle accumulation during replicative cell aging|positive regulation of extrachromosomal rDNA circle accumulation during replicative cell aging|up regulation of extrachromosomal rDNA circle accumulation involved in replicative cell aging	https://github.com/geneontology/go-ontology/issues/20007				This term was obsoleted because it represents an assay, not a true biological process.		se	2012-01-09T10:44:18Z		True			biological_process											owl:Class	
GO:1905566	biolink:NamedThing	obsolete negative regulation of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport	OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of receptor-mediated endocytosis of LDL|down-regulation of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport|negative regulation of receptor-mediated endocytosis of low-density lipoprotein involved in cholesterol transport|down-regulation of receptor-mediated endocytosis of LDL|downregulation of receptor-mediated endocytosis of low-density lipoprotein involved in cholesterol transport|inhibition of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport|down regulation of receptor-mediated endocytosis of low-density lipoprotein involved in cholesterol transport|downregulation of receptor-mediated endocytosis of LDL|inhibition of receptor-mediated endocytosis of low-density lipoprotein involved in cholesterol transport|down regulation of receptor-mediated endocytosis of LDL|down-regulation of receptor-mediated endocytosis of low-density lipoprotein involved in cholesterol transport|down regulation of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport|downregulation of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport|inhibition of receptor-mediated endocytosis of LDL					This term was obsoleted at the TermGenie Gatekeeper stage.		nc	2016-10-18T10:58:46Z		True			biological_process											owl:Class	
GO:0052114	biolink:NamedThing	obsolete adaptation to host pH environment	OBSOLETE. The responsive adjustment of an organism to the pH conditions in or around its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	adaptation to host pH environment|pH tolerance to host environment					This term was made obsolete because adaptation was not deemed to be a valid biological process.					True			biological_process											owl:Class	
GO:0001721	biolink:NamedThing	obsolete intermediate filament associated protein	OBSOLETE. Proteins that associate with intermediate filaments and function in the supramolecular organization of cellular intermediate filament networks.	tmpzr1t_l9r_go_relaxed.owl	intermediate filament associated protein|IFAP			GO:0005882		This term was made obsolete because it represents a single gene product and not a complex.					True			cellular_component											owl:Class	
causally_upstream_of	biolink:NamedThing	causally upstream of		tmpzr1t_l9r_go_relaxed.owl					RO:0002411									external									causally_upstream_of			
GO:0106183	biolink:NamedThing	obsolete translocase activity acting on carbohydrates and their derivatives.	OBSOLETE. Catalysis of the translocation of carbohydrates and their derivatives.	tmpzr1t_l9r_go_relaxed.owl					EC:7.5.-.-	This term was made obsolete because the concept of using the non-4 digit EC classes as parent terms for the transporter banch of the onotolgy was consided confusing.		hjd	2019-04-05T15:54:25Z		True			molecular_function											owl:Class	
GO:0018320	biolink:NamedThing	obsolete enzyme active site formation via S-methyl-L-cysteine	OBSOLETE. The transient methylation of peptidyl-cysteine to form S-methyl-L-cysteine.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/15594			RESID:AA0234	This term was obsoleted because it represents a reaction intermediate, not a biological process, see PMID:21527678.	GO:0008757				True			biological_process											owl:Class	
GO:0004214	biolink:NamedThing	obsolete dipeptidyl-peptidase I activity	OBSOLETE. Catalysis of the release of an N-terminal dipeptide, Xaa-Xbb from Xaa-Xbb-Xcc, except when Xaa is Arg or Lys, or Xbb or Xcc is Pro.	tmpzr1t_l9r_go_relaxed.owl	dipeptidyl-peptidase I activity|cathepsin C activity|DAP I|dipeptidyl transferase activity|dipeptide arylamidase I|dipeptidyl aminopeptidase I activity|cathepsin J activity				EC:3.4.14.1|MetaCyc:3.4.14.1-RXN	This term was made obsolete because it represents a gene product.	GO:0008234|GO:0008239				True			molecular_function											owl:Class	
GO:0060864	biolink:NamedThing	obsolete positive regulation of floral organ abscission by small GTPase mediated signal transduction	OBSOLETE. Any series of molecular signals in which a small monomeric GTPase relays one or more of the signals that increases the rate or extent of floral organ abscission.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/18200				This term was obsoleted because it does not represent a specific pathway.		dph	2009-08-12T04:34:56Z		True			biological_process											owl:Class	
GO:0070028	biolink:NamedThing	obsolete regulation of transcription by carbon monoxide	OBSOLETE. Any process involving carbon monoxide that modulates the frequency, rate or extent of transcription.	tmpzr1t_l9r_go_relaxed.owl	regulation of transcription by CO					This term was obsoleted because it represents a GO-CAM model.	GO:0006357				True			biological_process											owl:Class	
GO:0000763	biolink:NamedThing	obsolete cell morphogenesis involved in unidirectional conjugation	OBSOLETE. The change in form (cell shape and size) that occurs during sexual reproduction in order to facilitate direct contact between the compatible mating types in organisms that undergo unidirectional conjugation.	tmpzr1t_l9r_go_relaxed.owl	cell morphogenesis involved in unidirectional conjugation					This term was made obsolete because unidirectional conjugation occurs only in prokaryotes, which do not undergo morphogenetic changes associated with conjugation. In short, the process described by this term does not occur.					True			biological_process											owl:Class	
GO:0039603	biolink:NamedThing	obsolete TBP-class protein binding involved in viral suppression of host transcription initiation from RNA polymerase II promoter	OBSOLETE. Selective and non-covalent interaction of a viral protein with a member of the class of TATA-binding proteins (TBP) in the host, including any of the TBP-related factors (TRFs), which contributes to the viral-suppression of assembly of the RNA polymerase II preinitiation complex (PIC) at an RNA polymerase II promoter region of a host DNA template.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/14640				The reason for obsoletion is that the term is too specific, and the paper referenced in the term should instead be annotated to GO:0039602 ; suppression by virus of host transcription initiation from RNA polymerase II promoter.		bf	2012-07-05T04:00:15Z		True			molecular_function											owl:Class	
GO:0071511	biolink:NamedThing	obsolete inactivation of MAPK activity involved in conjugation with cellular fusion	OBSOLETE. Any process that terminates the activity of the active enzyme MAP kinase in the context of conjugation with cellular fusion.	tmpzr1t_l9r_go_relaxed.owl	conjugation with cellular fusion, inactivation of MAPK activity|termination of MAPK activity during conjugation with cellular fusion|inactivation of MAPK activity involved in mating response|conjugation with cellular fusion, termination of MAPK activity	https://github.com/geneontology/go-ontology/issues/20242				This term was obsoleted because it represents a GO-CAM model.		mah	2010-01-05T02:10:47Z		True			biological_process											owl:Class	
GO:0052424	biolink:NamedThing	obsolete modification by organism of symbiont morphology or physiology via protein secreted by type III secretion system	OBSOLETE. The process by which an organism effects a change in the structure or function of its symbiont organism, mediated by a substance secreted by a type III secretion system in the organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	modification by organism of symbiont morphology or physiology via protein secreted by type III secretion system					This term was made obsolete because it does not represent a real biological process.					True			biological_process											owl:Class	
GO:0010978	biolink:NamedThing	obsolete gene silencing involved in chronological cell aging	OBSOLETE. Any transcriptional or post-transcriptional process, arising in non-dividing cells as they age, carried out at the cellular level that results in long-term gene inactivation.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/18632				This term was obsoleted because it represent an assay - how long the cell lives -, not a true biological process.	GO:0090398|GO:0044838	tb	2009-06-01T11:39:42Z		True			biological_process											owl:Class	
GO:0070019	biolink:NamedThing	obsolete transforming growth factor beta type II receptor homodimeric complex	OBSOLETE. A receptor complex that consists of two transforming growth factor beta (TGF-beta) type II receptor monomers. TGF-beta type II receptor dimers form in the presence or absence of ligand, and upon ligand binding can associate with TGF-beta type I receptor dimers.	tmpzr1t_l9r_go_relaxed.owl	TGF-beta type II receptor dimer|transforming growth factor beta type II receptor complex|TGFBR2 homodimer|TGF-beta type II receptor complex	https://github.com/geneontology/go-ontology/issues/12676				This term was made obsolete because it does not represent a physiological complex.					True			cellular_component											owl:Class	
GO:0060277	biolink:NamedThing	obsolete negative regulation of transcription involved in G1 phase of mitotic cell cycle	OBSOLETE. Any process that stop, prevents or decreases transcription as part of the G1 phase of the mitotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of transcription from RNA polymerase II promoter during G1 phase of mitotic cell cycle|negative regulation of transcription involved in G1 phase of mitotic cell cycle					This term was made obsolete because it is unclear exactly what it means. It could mean either 'regulation of transcription during phase X' or 'regulation of transition between phase X and phase Y'.	GO:0000122|GO:0071930				True			biological_process											owl:Class	
GO:0071552	biolink:NamedThing	obsolete RIP homotypic interaction motif-mediated complex assembly	OBSOLETE. A process of protein complex assembly in which the arrangement and bonding together of the set of components that form the protein complex is mediated by a RIP homotypic interaction motif (RHIM) interaction.	tmpzr1t_l9r_go_relaxed.owl	RHIM-mediated complex assembly					This term was obsoleted because it represented a molecular function (binding), not a biological process.  The term represented a domain involved in protein-protein interactions, but no necessarily the process of assembling a complex.		mah	2010-01-13T03:08:30Z		True			biological_process											owl:Class	
GO:0015337	biolink:NamedThing	obsolete low affinity metal ion uptake transporter activity	OBSOLETE. Catalysis of the reaction: Me2+(out) + H+(out) = Me2+(in) + H+(in). Me can be Mn2+ or Cu2+.	tmpzr1t_l9r_go_relaxed.owl	low affinity metal ion uptake transporter activity					This term was made obsolete because it represents a gene product and not a molecular function.	GO:0046873|GO:0015295				True			molecular_function											owl:Class	
GO:0039549	biolink:NamedThing	obsolete suppression by virus of host IRF3 activity by inhibition of IRF3 phosphorylation	OBSOLETE. Any process in which a virus stops, prevents, or reduces the rate or extent of the phosphorylation of IRF3 (interferon regulatory factor-3), thereby inhibiting IRF3 activation. In response to signaling from RIG-1/MDA-5 receptors, IRF3 is phosphorylated on multiple serine and threonine residues; phosphorylation results in the cytoplasm-to-nucleus translocation of IRF3, DNA binding, and increased transcriptional activation of interferon-encoding genes.	tmpzr1t_l9r_go_relaxed.owl	inhibition of virus-induced IRF-3 phosphorylation|inhibition of phosphorylation-induced activation of host IRF3					The reason for obsoleting this term is that it is too specific. The exact molecular roles of the individual proteins should be captured separately.		bf	2012-01-19T04:27:06Z		True			biological_process											owl:Class	
GO:0016804	biolink:NamedThing	obsolete prolyl aminopeptidase activity	OBSOLETE. Catalysis of the release of a N-terminal proline from a peptide.	tmpzr1t_l9r_go_relaxed.owl	proline aminopeptidase|cytosol aminopeptidase V|prolyl aminopeptidase activity|proline iminopeptidase activity|Pro-X aminopeptidase activity			GO:0004177		This term was made obsolete because it represents a gene product, and the substrate specificity it refers to is not cleanly defined.					True			molecular_function											owl:Class	
GO:0045564	biolink:NamedThing	obsolete positive regulation of TRAIL receptor biosynthetic process	OBSOLETE. Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of the TRAIL (TNF-related apoptosis inducing ligand) receptor.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of TRAIL receptor anabolism|upregulation of TRAIL receptor biosynthetic process|positive regulation of TRAIL receptor formation|positive regulation of TRAIL receptor synthesis|up-regulation of TRAIL receptor biosynthetic process|positive regulation of TRAIL receptor biosynthesis|activation of TRAIL receptor biosynthetic process|up regulation of TRAIL receptor biosynthetic process|stimulation of TRAIL receptor biosynthetic process	https://github.com/geneontology/go-ontology/issues/19900				The reason for obsoletion is that those represent specific gene products, and genes annotated to those terms should be annotated to 'regulation of gene expression' or 'regulation of transcription' or some signaling term.					True			biological_process											owl:Class	
GO:0100020	biolink:NamedThing	obsolete regulation of transport by transcription from RNA polymerase II promoter	OBSOLETE. Any transcription from RNA polymerase II promoter process that regulates transport.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it represents a GO-CAM model.		cjm	2015-04-02T04:13:19Z		True			biological_process											owl:Class	
GO:0001722	biolink:NamedThing	obsolete type I intermediate filament associated protein	OBSOLETE. Low molecular weight (10-45 kDa) proteins that associate with intermediate filaments by lateral binding of the filaments and have the effect of creating tight macrofilament aggregates.	tmpzr1t_l9r_go_relaxed.owl	type I intermediate filament associated protein			GO:0005882		This term was made obsolete because it represents a single gene product and not a complex.					True			cellular_component											owl:Class	
GO:0039543	biolink:NamedThing	obsolete suppression by virus of host RIG-I activity by viral RNA 5' processing	OBSOLETE. The post-transcriptional removal by a virus of the 5' triphosphate group of their viral RNA, thereby preventing host RIG-I from recognizing viral RNA in the host cell. The intracellular pattern recognition receptor RIG-I (also known as DDX58) recognizes viral RNAs containing 5' triphosphates; removal by the virus of the 5'-terminal triphosphate group from their genome protects the viral RNA from RIG-recognition.	tmpzr1t_l9r_go_relaxed.owl	suppression by virus of host RIG-I activity by inhibition of RNA binding					The reason for obsoleting this term is that it is too specific. The exact molecular roles of the individual proteins should be captured separately.		bf	2012-01-18T02:30:29Z		True			biological_process											owl:Class	
GO:0005567	biolink:NamedThing	obsolete cytosolic ribosomal RNA	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	cytosolic ribosomal RNA					Note that this term was deleted from GO and was restored to the ontology in Feb 2003 to ensure that the ID is not reused.					True			cellular_component											owl:Class	
GO:0052415	biolink:NamedThing	obsolete metabolism by organism of glucan in other organism involved in symbiotic interaction	OBSOLETE. The chemical reactions and pathways performed by an organism involving glucans within a second organism, where the two organisms are in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	metabolism by organism of glucan in other organism during symbiotic interaction	https://github.com/geneontology/go-ontology/issues/21396				This term was obsoleted because it represents an unnecessary grouping class.					True			biological_process											owl:Class	
GO:0031660	biolink:NamedThing	obsolete regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle	OBSOLETE. Any process that modulates the frequency, rate or extent of cyclin-dependent protein serine/threonine kinase activity contributing to the G2/M transition of the cell cycle.	tmpzr1t_l9r_go_relaxed.owl	G2/M-specific regulation of cyclin-dependent protein kinase activity|regulation of cyclin-dependent protein kinase activity involved in G2/M|regulation of cyclin-dependent protein kinase activity during G2/M					This term was obsoleted because it is a MF represented as a BP.	GO:0010389				True			biological_process											owl:Class	
GO:1902625	biolink:NamedThing	obsolete negative regulation of induction of conjugation with cellular fusion by negative regulation of transcription from RNA polymerase II promoter	OBSOLETE. A negative regulation of transcription from RNA polymerase II promoter that results in negative regulation of induction of conjugation with cellular fusion.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it represents a GO-CAM model.		mah	2014-01-16T13:52:24Z		True			biological_process											owl:Class	
GO:1904111	biolink:NamedThing	obsolete negative regulation of plus-end directed microfilament motor activity	OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of plus-end directed microfilament motor activity.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of plus-end directed actin-filament motor activity|downregulation of plus-end directed microfilament motor activity|down regulation of plus-end directed actin-filament motor activity|downregulation of barbed-end directed actin-filament motor activity|down-regulation of barbed-end directed actin-filament motor activity|down regulation of plus-end directed actin filament motor activity|negative regulation of barbed-end directed actin-filament motor activity|down-regulation of plus-end directed microfilament motor activity|down regulation of plus-end directed microfilament motor activity|down regulation of barbed-end directed actin-filament motor activity|inhibition of plus-end directed microfilament motor activity|inhibition of barbed-end directed actin-filament motor activity|inhibition of plus-end directed actin-filament motor activity|negative regulation of plus-end directed actin-filament motor activity|inhibition of plus-end directed actin filament motor activity|down-regulation of plus-end directed actin filament motor activity|downregulation of plus-end directed actin-filament motor activity|downregulation of plus-end directed actin filament motor activity|negative regulation of plus-end directed actin filament motor activity	https://github.com/geneontology/go-ontology/issues/21626				This term was obsoleted because it represents a molecular function.	GO:0140661	kmv	2015-04-03T18:28:30Z		True			biological_process											owl:Class	
GO:0015076	biolink:NamedThing	obsolete heavy metal ion transporter activity	OBSOLETE. Enables the directed movement of heavy metal ions into, out of or within a cell, or between cells. Heavy metals are those that can form a coordination bond with a protein, as opposed to an alkali or alkaline-earth metal that can only form an ionic bond; this definition includes the following biologically relevant heavy metals: Cd, Co, Cu, Fe, Hg, Mn, Mo, Ni, V, W, Zn.	tmpzr1t_l9r_go_relaxed.owl	heavy metal ion transporter activity					This term was made obsolete because 'heavy metal' is an ambiguous grouping term which has no set meaning (see Pure Appl. Chem. Vol. 74, No. 5, pp. 793-807, 2002, for more information).	GO:0046873				True			molecular_function											owl:Class	
GO:1903150	biolink:NamedThing	obsolete calcium ion transmembrane transporter activity involved in calcium ion import into cell	OBSOLETE. Any calcium ion transmembrane transporter activity that is involved in calcium ion import into cell.	tmpzr1t_l9r_go_relaxed.owl	calcium ion transmembrane transporter activity involved in calcium ion uptake into cell|calcium ion transmembrane transporter activity involved in calcium ion import into cell					This term was obsoleted at the TermGenie Gatekeeper stage.		dos	2014-07-09T11:55:36Z		True			molecular_function											owl:Class	
GO:0052332	biolink:NamedThing	obsolete modification by organism of membrane in other organism involved in symbiotic interaction	OBSOLETE. The process in which an organism effects a change in the structure or function of a cellular membrane of a second organism, where the two organisms are in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	modification by organism of cell membrane in other organism involved in symbiotic interaction|modification by organism of cell membrane in other organism during symbiotic interaction					This term was obsoleted because it represents an unnecessary grouping class.					True			biological_process											owl:Class	
GO:0008651	biolink:NamedThing	obsolete actin polymerizing activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	actin polymerizing activity					This term was made obsolete because it represents a biological process.	GO:0030041|GO:0042802				True			molecular_function											owl:Class	
GO:0008162	biolink:NamedThing	obsolete cyclodiene resistance	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	cyclodiene resistance			GO:0046682		This term was made obsolete because 'resistance' implies a phenotype rather than a biological process.					True			biological_process											owl:Class	
GO:0023069	biolink:NamedThing	obsolete signal transmission via xylem	OBSOLETE. The process in which a signal is conveyed via the xylem.	tmpzr1t_l9r_go_relaxed.owl	signal transmission via xylem					This term was made obsolete because the meaning of the term is ambiguous.	GO:0023052|GO:0010232		2010-02-16T09:30:50Z		True			biological_process											owl:Class	
GO:0045714	biolink:NamedThing	obsolete regulation of low-density lipoprotein particle receptor biosynthetic process	OBSOLETE. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of low-density lipoprotein particle receptors.	tmpzr1t_l9r_go_relaxed.owl	regulation of LDLr biosynthesis|regulation of low-density lipoprotein receptor biosynthetic process|regulation of LDLr biosynthetic process|regulation of low-density lipoprotein receptor formation|regulation of low-density lipoprotein receptor synthesis|regulation of low-density lipoprotein receptor anabolism|regulation of low-density lipoprotein receptor biosynthesis	https://github.com/geneontology/go-ontology/issues/19900				The reason for obsoletion is that those represent specific gene products, and genes annotated to those terms should be annotated to 'regulation of gene expression' or 'regulation of transcription' or some signaling term.					True			biological_process											owl:Class	
GO:0042057	biolink:NamedThing	obsolete transforming growth factor beta receptor anchoring activity	OBSOLETE. Binds to transforming growth factor beta receptor and anchors it to a particular subcellular location.	tmpzr1t_l9r_go_relaxed.owl	TGFbeta receptor anchoring activity|TGF-beta receptor anchoring activity|transforming growth factor beta receptor anchor activity|transforming growth factor beta receptor anchoring activity					This term was made obsolete because it represents a combination of process and function information.	GO:0008104|GO:0005160				True			molecular_function											owl:Class	
GO:0052046	biolink:NamedThing	obsolete modification by symbiont of host morphology or physiology via secreted substance	OBSOLETE. The process in which an organism effects a change in the structure or function of its host organism, mediated by a substance secreted by one of the organisms. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	modification of host morphology or physiology via ellicitor|modification of host morphology or physiology via effector molecule					This term was obsoleted because it conflated the process in which a gene product is involved with the secretion system by which it reaches its target.					True			biological_process											owl:Class	
GO:0052368	biolink:NamedThing	obsolete disruption by organism of cellular component in other organism involved in symbiotic interaction	OBSOLETE. The chemical reactions and pathways performed by an organism resulting in the breakdown of cellular components of a second organism, where the two organisms are in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	degradation of cellular component in other organism|catabolism of structural constituent in other organism|disassembly by organism of cellular component in other organism involved in symbiotic interaction|disassembly by organism of cellular component in other organism during symbiotic interaction|catabolism of cellular component in other organism					This term was obsoleted because it represents an unnecessary grouping class.					True			biological_process											owl:Class	
GO:0035948	biolink:NamedThing	obsolete positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter	OBSOLETE. Any process that activates or increases the frequency, rate or extent of gluconeogenesis by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter.	tmpzr1t_l9r_go_relaxed.owl	regulation of glucose biosynthesis by upregulation of transcription from RNA polymerase II promoter|regulation of gluconeogenesis by positive regulation of transcription from Pol II promoter|regulation of glucose biosynthetic process by upregulation of transcription from RNA polymerase II promoter|regulation of glucose biosynthetic process by positive regulation of transcription from RNA polymerase II promoter|regulation of glucose biosynthesis by positive regulation of transcription from Pol II promoter|regulation of gluconeogenesis by activation of transcription from RNA polymerase II promoter|regulation of glucose biosynthetic process by positive regulation of transcription from Pol II promoter|regulation of glucose biosynthesis by up regulation of transcription from RNA polymerase II promoter|regulation of gluconeogenesis by upregulation of transcription from RNA polymerase II promoter|regulation of glucose biosynthesis by positive regulation of transcription from RNA polymerase II promoter|regulation of glucose biosynthetic process by up regulation of transcription from RNA polymerase II promoter|regulation of gluconeogenesis by up-regulation of transcription from RNA polymerase II promoter|regulation of glucose biosynthesis by up-regulation of transcription from RNA polymerase II promoter|regulation of gluconeogenesis by up regulation of transcription from RNA polymerase II promoter|regulation of glucose biosynthetic process by up-regulation of transcription from RNA polymerase II promoter|regulation of gluconeogenesis by stimulation of transcription from RNA polymerase II promoter					This term was obsoleted because it represents a GO-CAM model.		bf			True			biological_process											owl:Class	
GO:0052137	biolink:NamedThing	obsolete aerotaxis in host	OBSOLETE. The movement of a motile cell or organism in response to environmental oxygen within its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	aerotaxis within host	https://github.com/geneontology/go-ontology/issues/18819				This term was obsoleted because it represents both a process and a location.					True			biological_process											owl:Class	
GO:0004277	biolink:NamedThing	obsolete granzyme A activity	OBSOLETE. Catalysis of the hydrolysis of proteins, including fibronectin, type IV collagen and nucleolin. Preferential cleavage: Arg-Xaa > Lys-Xaa > Phe-Xaa in small molecule substrates.	tmpzr1t_l9r_go_relaxed.owl	TSP-1|CTLA3|cytotoxic T-lymphocyte proteinase 1 activity|HuTPS|T-cell associated protease 1|cytotoxic T lymphocyte serine protease|T-cell derived serine proteinase|granzyme A activity			GO:0004252		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:1903240	biolink:NamedThing	obsolete negative regulation of positive regulation of the force of heart contraction by chemical signal	OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of positive regulation of the force of heart contraction by chemical signal.	tmpzr1t_l9r_go_relaxed.owl	downregulation of positive regulation of the force of heart muscle contraction by chemical signal|inhibition of positive regulation of the force of heart muscle contraction by chemical signal|down regulation of positive regulation of the force of heart muscle contraction by chemical signal|negative regulation of positive regulation of the force of heart muscle contraction by chemical signal|downregulation of positive regulation of the force of heart contraction by chemical signal|down-regulation of positive regulation of the force of heart contraction by chemical signal|down-regulation of positive regulation of the force of heart muscle contraction by chemical signal|negative regulation of positive regulation of the force of heart contraction by chemical signal|inhibition of positive regulation of the force of heart contraction by chemical signal|down regulation of positive regulation of the force of heart contraction by chemical signal					This term was obsoleted at the TermGenie Gatekeeper stage.		rl	2014-07-31T17:00:23Z		True			biological_process											owl:Class	
GO:0003784	biolink:NamedThing	obsolete barbed-end actin capping/severing activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	barbed-end actin capping/severing activity					This term was made obsolete because it describes two biological processes.	GO:0051014|GO:0051016				True			molecular_function											owl:Class	
GO:0052583	biolink:NamedThing	obsolete oxidoreductase activity, acting on halogen in donors	OBSOLETE. Catalysis of an oxidation-reduction in which a halogen in the donor substance acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/20613			EC:1.22.-.-	This term was obsoleted because EC obsoleted it, and there was no other evidence that this function exists.			2010-08-13T10:14:12Z		True			molecular_function											owl:Class	
GO:0085005	biolink:NamedThing	obsolete interaction with host via secreted substance released from invasive hyphae	OBSOLETE. An interaction with the host organism mediated by a substance released by the other (symbiont) organism via invasive hyphae. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl						This term was deprecated because it conflated the process in which a gene product is involved with the secretion system by which it reaches its target.		jl	2010-02-10T02:59:51Z		True			biological_process											owl:Class	
GO:0008822	biolink:NamedThing	obsolete crotonobetaine/carnitine-CoA ligase activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	crotonobetaine/carnitine-CoA ligase activity					This term was made obsolete because it represents a bifunctional gene product.	GO:0051108|GO:0051109				True			molecular_function											owl:Class	
GO:0009580	biolink:NamedThing	obsolete thylakoid (sensu Bacteria)	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	thylakoid (sensu Bacteria)					This term was made obsolete because more specific children exist.	GO:0042716|GO:0030075				True			cellular_component											owl:Class	
GO:0004050	biolink:NamedThing	obsolete apyrase activity	OBSOLETE. Catalysis of the reaction: ATP + 2 H2O = AMP + 2 phosphate.	tmpzr1t_l9r_go_relaxed.owl	apyrase activity					This term was made obsolete because it represents a gene product which can catalyze two reactions.	GO:0017111|GO:0017110				True			molecular_function											owl:Class	
GO:1904079	biolink:NamedThing	obsolete negative regulation of transcription from RNA polymerase II promoter involved in negative regulation of neuron apoptotic process	OBSOLETE. Any negative regulation of transcription from RNA polymerase II promoter that is involved in negative regulation of neuron apoptotic process.	tmpzr1t_l9r_go_relaxed.owl	inhibition of global transcription from RNA polymerase II promoter involved in down regulation of neuron apoptosis|negative regulation of transcription from RNA polymerase II promoter involved in negative regulation of neuron apoptotic process|down regulation of transcription from RNA polymerase II promoter involved in negative regulation of neuron apoptotic process|down-regulation of transcription from RNA polymerase II promoter involved in negative regulation of neuron apoptosis|down regulation of transcription from RNA polymerase II promoter involved in down-regulation of neuron apoptosis|down regulation of global transcription from RNA polymerase II promoter involved in negative regulation of neuron apoptotic process|negative regulation of global transcription from Pol II promoter involved in negative regulation of neuron apoptotic process|downregulation of transcription from RNA polymerase II promoter involved in inhibition of neuron apoptosis|inhibition of transcription from RNA polymerase II promoter involved in neuron survival|down-regulation of global transcription from RNA polymerase II promoter involved in inhibition of neuron apoptosis|negative regulation of gene-specific transcription from RNA polymerase II promoter involved in negative regulation of programmed cell death, neurons|negative regulation of global transcription from Pol II promoter involved in neuron survival|down regulation of global transcription from RNA polymerase II promoter involved in down-regulation of neuron apoptosis|down-regulation of transcription from RNA polymerase II promoter involved in negative regulation of neuron apoptotic process|down-regulation of global transcription from RNA polymerase II promoter involved in neuron survival|down-regulation of transcription from RNA polymerase II promoter involved in downregulation of neuron apoptosis|down regulation of global transcription from RNA polymerase II promoter involved in inhibition of neuron apoptosis|down regulation of transcription from RNA polymerase II promoter involved in negative regulation of neuron apoptosis|down-regulation of transcription from RNA polymerase II promoter involved in neuron survival|down regulation of transcription from RNA polymerase II promoter involved in downregulation of neuron apoptosis|down regulation of transcription from RNA polymerase II promoter involved in down regulation of neuron apoptosis|negative regulation of gene-specific transcription from RNA polymerase II promoter involved in down-regulation of neuron apoptosis|inhibition of transcription from RNA polymerase II promoter involved in negative regulation of neuron apoptosis|negative regulation of transcription from Pol II promoter involved in negative regulation of neuron apoptosis|down regulation of transcription from RNA polymerase II promoter involved in negative regulation of programmed cell death, neurons|negative regulation of gene-specific transcription from RNA polymerase II promoter involved in down regulation of neuron apoptosis|negative regulation of transcription from Pol II promoter involved in negative regulation of neuron apoptotic process|down-regulation of global transcription from RNA polymerase II promoter involved in down-regulation of neuron apoptosis|negative regulation of gene-specific transcription from RNA polymerase II promoter involved in downregulation of neuron apoptosis|negative regulation of transcription from RNA polymerase II promoter, global involved in negative regulation of programmed cell death, neurons|downregulation of transcription from RNA polymerase II promoter involved in downregulation of neuron apoptosis|down-regulation of global transcription from RNA polymerase II promoter involved in negative regulation of neuron apoptotic process|down regulation of global transcription from RNA polymerase II promoter involved in down regulation of neuron apoptosis|negative regulation of gene-specific transcription from RNA polymerase II promoter involved in negative regulation of neuron apoptotic process|downregulation of transcription from RNA polymerase II promoter involved in negative regulation of programmed cell death, neurons|inhibition of global transcription from RNA polymerase II promoter involved in negative regulation of neuron apoptosis|negative regulation of global transcription from Pol II promoter involved in downregulation of neuron apoptosis|down-regulation of transcription from RNA polymerase II promoter involved in negative regulation of programmed cell death, neurons|negative regulation of transcription from RNA polymerase II promoter, global involved in inhibition of neuron apoptosis|negative regulation of transcription from RNA polymerase II promoter, global involved in downregulation of neuron apoptosis|down-regulation of global transcription from RNA polymerase II promoter involved in downregulation of neuron apoptosis|downregulation of global transcription from RNA polymerase II promoter involved in inhibition of neuron apoptosis|negative regulation of transcription from RNA polymerase II promoter, global involved in down regulation of neuron apoptosis|inhibition of global transcription from RNA polymerase II promoter involved in inhibition of neuron apoptosis|downregulation of transcription from RNA polymerase II promoter involved in down-regulation of neuron apoptosis|downregulation of transcription from RNA polymerase II promoter involved in neuron survival|down-regulation of transcription from RNA polymerase II promoter involved in inhibition of neuron apoptosis|down regulation of global transcription from RNA polymerase II promoter involved in downregulation of neuron apoptosis|negative regulation of global transcription from Pol II promoter involved in down regulation of neuron apoptosis|inhibition of transcription from RNA polymerase II promoter involved in downregulation of neuron apoptosis|negative regulation of transcription from Pol II promoter involved in negative regulation of programmed cell death, neurons|negative regulation of global transcription from Pol II promoter involved in negative regulation of neuron apoptosis|inhibition of global transcription from RNA polymerase II promoter involved in neuron survival|negative regulation of transcription from Pol II promoter involved in down-regulation of neuron apoptosis|downregulation of global transcription from RNA polymerase II promoter involved in negative regulation of neuron apoptotic process|negative regulation of transcription from Pol II promoter involved in inhibition of neuron apoptosis|downregulation of global transcription from RNA polymerase II promoter involved in down regulation of neuron apoptosis|negative regulation of transcription from Pol II promoter involved in downregulation of neuron apoptosis|inhibition of transcription from RNA polymerase II promoter involved in down regulation of neuron apoptosis|negative regulation of gene-specific transcription from RNA polymerase II promoter involved in neuron survival|negative regulation of transcription from RNA polymerase II promoter involved in neuron survival|negative regulation of transcription from RNA polymerase II promoter, global involved in down-regulation of neuron apoptosis|downregulation of transcription from RNA polymerase II promoter involved in negative regulation of neuron apoptosis|negative regulation of transcription from Pol II promoter involved in neuron survival|down regulation of transcription from RNA polymerase II promoter involved in inhibition of neuron apoptosis|downregulation of global transcription from RNA polymerase II promoter involved in negative regulation of programmed cell death, neurons|down-regulation of global transcription from RNA polymerase II promoter involved in down regulation of neuron apoptosis|downregulation of global transcription from RNA polymerase II promoter involved in negative regulation of neuron apoptosis|negative regulation of transcription from RNA polymerase II promoter involved in negative regulation of programmed cell death, neurons|negative regulation of transcription from RNA polymerase II promoter, global involved in neuron survival|negative regulation of global transcription from Pol II promoter involved in down-regulation of neuron apoptosis|negative regulation of transcription from RNA polymerase II promoter, global involved in negative regulation of neuron apoptosis|negative regulation of transcription from RNA polymerase II promoter, global involved in negative regulation of neuron apoptotic process|inhibition of transcription from RNA polymerase II promoter involved in inhibition of neuron apoptosis|inhibition of global transcription from RNA polymerase II promoter involved in downregulation of neuron apoptosis|negative regulation of global transcription from Pol II promoter involved in inhibition of neuron apoptosis|downregulation of transcription from RNA polymerase II promoter involved in down regulation of neuron apoptosis|down regulation of global transcription from RNA polymerase II promoter involved in negative regulation of neuron apoptosis|down-regulation of global transcription from RNA polymerase II promoter involved in negative regulation of programmed cell death, neurons|downregulation of global transcription from RNA polymerase II promoter involved in downregulation of neuron apoptosis|inhibition of transcription from RNA polymerase II promoter involved in down-regulation of neuron apoptosis|inhibition of global transcription from RNA polymerase II promoter involved in down-regulation of neuron apoptosis|down regulation of global transcription from RNA polymerase II promoter involved in neuron survival|downregulation of global transcription from RNA polymerase II promoter involved in neuron survival|inhibition of transcription from RNA polymerase II promoter involved in negative regulation of programmed cell death, neurons|down-regulation of global transcription from RNA polymerase II promoter involved in negative regulation of neuron apoptosis|down-regulation of transcription from RNA polymerase II promoter involved in down regulation of neuron apoptosis|down regulation of global transcription from RNA polymerase II promoter involved in negative regulation of programmed cell death, neurons|negative regulation of transcription from RNA polymerase II promoter involved in inhibition of neuron apoptosis|down regulation of transcription from RNA polymerase II promoter involved in neuron survival|inhibition of global transcription from RNA polymerase II promoter involved in negative regulation of neuron apoptotic process|downregulation of transcription from RNA polymerase II promoter involved in negative regulation of neuron apoptotic process|negative regulation of transcription from RNA polymerase II promoter involved in downregulation of neuron apoptosis|negative regulation of gene-specific transcription from RNA polymerase II promoter involved in inhibition of neuron apoptosis|negative regulation of transcription from Pol II promoter involved in down regulation of neuron apoptosis|down-regulation of transcription from RNA polymerase II promoter involved in down-regulation of neuron apoptosis|negative regulation of transcription from RNA polymerase II promoter involved in down regulation of neuron apoptosis|downregulation of global transcription from RNA polymerase II promoter involved in down-regulation of neuron apoptosis|negative regulation of global transcription from Pol II promoter involved in negative regulation of programmed cell death, neurons|inhibition of transcription from RNA polymerase II promoter involved in negative regulation of neuron apoptotic process|negative regulation of transcription from RNA polymerase II promoter involved in negative regulation of neuron apoptosis|negative regulation of gene-specific transcription from RNA polymerase II promoter involved in negative regulation of neuron apoptosis|negative regulation of transcription from RNA polymerase II promoter involved in down-regulation of neuron apoptosis|inhibition of global transcription from RNA polymerase II promoter involved in negative regulation of programmed cell death, neurons					This term was obsoleted at the TermGenie Gatekeeper stage.	GO:0000122|GO:0043524	kmv	2015-03-24T17:28:41Z		True			biological_process											owl:Class	
GO:0051405	biolink:NamedThing	obsolete microbial collagenase activity	OBSOLETE. Catalysis of the digestion of native collagen in the triple helical region at Xaa-Gly bonds.	tmpzr1t_l9r_go_relaxed.owl	matirx metalloproteinase-18|matrix metalloproteinase-1|Clostridium histolyticum proteinase A|Clostridium histolyticum collagenase activity|collagen peptidase activity|azocollase activity|collagen protease activity|collagenase MMP-1|metalloproteinase-1|kollaza|matrix metalloproteinase-8|soycollagestin|clostridiopeptidase II|collagenase I activity|nucleolysin|Achromobacter iophagus collagenase|collagenase 1 activity|clostridiopeptidase I|microbial collagenase activity|aspergillopeptidase C|metallocollagenase activity|collagenase A activity|clostridiopeptidase A activity			GO:0004252		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0043947	biolink:NamedThing	obsolete positive regulation by host of symbiont catalytic activity	OBSOLETE. Any process in which an organism activates, maintains or increases the frequency, rate or extent of symbiont enzyme activity. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	up-regulation by host of symbiont enzyme activity|upregulation by host of symbiont enzyme activity|activation of symbiont enzyme activity|up regulation by host of symbiont enzyme activity|positive regulation by host of symbiont enzyme activity|activation by host of symbiont enzyme activity	https://github.com/geneontology/go-ontology/issues/21740				This term was obsoleted because it represents a molecular function.					True			biological_process											owl:Class	
GO:1901572	biolink:NamedThing	obsolete chemical substance metabolic process	OBSOLETE. The chemical reactions and pathways involving chemical substance.	tmpzr1t_l9r_go_relaxed.owl	chemical substance metabolic process|chemical substance metabolism					This term was obsoleted at the TermGenie Gatekeeper stage.		pr	2012-11-04T18:10:32Z		True			biological_process											owl:Class	
GO:1904771	biolink:NamedThing	obsolete cellular response to doxorubicin	OBSOLETE. Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a doxorubicin stimulus.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted at the TermGenie Gatekeeper stage.		sl	2015-10-28T20:48:30Z		True			biological_process											owl:Class	
GO:0018308	biolink:NamedThing	obsolete enzyme active site formation via N6-pyruvic acid 2-iminyl-L-lysine	OBSOLETE. The transient modification of lysine by pyruvate to form N6-pyruvic acid 2-iminyl-L-lysine, found in the active site of dihydrodipicolinate synthase.	tmpzr1t_l9r_go_relaxed.owl	enzyme active site formation via N6-pyruvic acid 2-iminyl-L-lysine					This term was made obsolete because this process does not occur: the modification occurs before it can be an active site.					True			biological_process											owl:Class	
GO:0008633	biolink:NamedThing	obsolete activation of pro-apoptotic gene products	OBSOLETE. The conversion of proteins that induce or sustain apoptosis to an active form.	tmpzr1t_l9r_go_relaxed.owl	activation of pro-apoptotic gene products|induction of pro-apoptotic gene products					This term was made obsolete because more specific terms were created. Additionally, the meaning of the term is ambiguous (some gene products may be involved in apoptosis, or not, depending on cell type, tissue, condition).					True			biological_process											owl:Class	
GO:0085011	biolink:NamedThing	obsolete interaction with host via protein secreted by Sec complex	OBSOLETE. An interaction with the host organism mediated by a substance secreted by the symbiont organism by a Sec complex. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	interaction with host via protein secreted by Sec secretion system					This term was obsoleted because it conflated the process in which a gene product is involved with the secretion system by which it reaches its target.		jl	2010-02-10T03:18:36Z		True			biological_process											owl:Class	
GO:0035424	biolink:NamedThing	obsolete MAPK import into nucleus involved in innate immune response	OBSOLETE. The directed movement of a MAP kinase to the nucleus in the context of an innate immune response, a defense response mediated by germline encoded components that directly recognize components of potential pathogens.	tmpzr1t_l9r_go_relaxed.owl	nuclear translocation of MAPK involved in innate immune response					The reason for obsoletion is that this term represents a GO-CAM model.	GO:0006606	bf	2010-03-29T01:29:36Z		True			biological_process											owl:Class	
GO:0052249	biolink:NamedThing	obsolete modulation of RNA levels in other organism involved in symbiotic interaction	OBSOLETE. The alteration by an organism of the levels of RNA in a second organism, where the two organisms are in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	modulation of RNA levels in other organism during symbiotic interaction					This term was obsoleted because it represents an unnecessary grouping class.					True			biological_process											owl:Class	
GO:0052334	biolink:NamedThing	obsolete modification by organism of cytoskeleton of other organism involved in symbiotic interaction	OBSOLETE. The process in which an organism effects a change in the structure or function of the cytoskeleton of a second organism, where the two organisms are in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	modification by organism of cytoskeleton of other organism during symbiotic interaction					This term was obsoleted because it represents an unnecessary grouping class.					True			biological_process											owl:Class	
GO:0008350	biolink:NamedThing	obsolete kinetochore motor activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	kinetochore motor activity					This term was made obsolete because it includes cellular component information.	GO:0000776|GO:0003777				True			molecular_function											owl:Class	
GO:0072368	biolink:NamedThing	obsolete regulation of lipid transport by negative regulation of transcription from RNA polymerase II promoter	OBSOLETE. Any process that modulates the frequency, rate or extent of lipid transport by stopping, preventing, or reducing the frequency, rate or extent of transcription from an RNA polymerase II promoter.	tmpzr1t_l9r_go_relaxed.owl	regulation of lipid transport by negative regulation of transcription from an RNA polymerase II promoter					This term was obsoleted because it represents a GO-CAM model.		mah	2010-11-16T03:18:13Z		True			biological_process											owl:Class	
GO:1900525	biolink:NamedThing	obsolete positive regulation of phosphatidylserine biosynthetic process by positive regulation of transcription from RNA polymerase II promoter	OBSOLETE. Any process that activates or increases the frequency, rate or extent of phosphatidylserine biosynthetic process by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of phosphatidylserine anabolism by positive regulation of transcription from RNA polymerase II promoter|activation of phosphatidylserine anabolism by positive regulation of transcription from RNA polymerase II promoter|up regulation of phosphatidylserine formation by positive regulation of transcription from RNA polymerase II promoter|upregulation of phosphatidylserine formation by positive regulation of transcription from RNA polymerase II promoter|upregulation of phosphatidylserine biosynthesis by positive regulation of transcription from RNA polymerase II promoter|up regulation of phosphatidylserine biosynthesis by positive regulation of transcription from RNA polymerase II promoter|activation of phosphatidylserine biosynthetic process by positive regulation of transcription from RNA polymerase II promoter|activation of phosphatidylserine formation by positive regulation of transcription from RNA polymerase II promoter|up-regulation of phosphatidylserine synthesis by positive regulation of transcription from RNA polymerase II promoter|up regulation of phosphatidylserine anabolism by positive regulation of transcription from RNA polymerase II promoter|positive regulation of phosphatidylserine formation by positive regulation of transcription from RNA polymerase II promoter|activation of phosphatidylserine biosynthesis by positive regulation of transcription from RNA polymerase II promoter|up-regulation of phosphatidylserine formation by positive regulation of transcription from RNA polymerase II promoter|upregulation of phosphatidylserine biosynthetic process by positive regulation of transcription from RNA polymerase II promoter|up-regulation of phosphatidylserine biosynthetic process by positive regulation of transcription from RNA polymerase II promoter|up-regulation of phosphatidylserine anabolism by positive regulation of transcription from RNA polymerase II promoter|up regulation of phosphatidylserine synthesis by positive regulation of transcription from RNA polymerase II promoter|upregulation of phosphatidylserine anabolism by positive regulation of transcription from RNA polymerase II promoter|up regulation of phosphatidylserine biosynthetic process by positive regulation of transcription from RNA polymerase II promoter|upregulation of phosphatidylserine synthesis by positive regulation of transcription from RNA polymerase II promoter|positive regulation of phosphatidylserine synthesis by positive regulation of transcription from RNA polymerase II promoter|positive regulation of phosphatidylserine biosynthesis by positive regulation of transcription from RNA polymerase II promoter|activation of phosphatidylserine synthesis by positive regulation of transcription from RNA polymerase II promoter|up-regulation of phosphatidylserine biosynthesis by positive regulation of transcription from RNA polymerase II promoter					This term was obsoleted because it represents a GO-CAM model.		dgf	2012-05-03T05:13:55Z		True			biological_process											owl:Class	
GO:0030484	biolink:NamedThing	obsolete muscle fiber	OBSOLETE. The contractile fibers, composed of actin, myosin, and associated proteins, found in cells of smooth or striated muscle.	tmpzr1t_l9r_go_relaxed.owl	muscle fiber|muscle fibre					This term was made obsolete because a muscle fiber is a cell type rather than a cell component. To update annotations, consider the external ontology term 'muscle cell ; CL:0000187'.	GO:0043292				True			cellular_component											owl:Class	
GO:1903246	biolink:NamedThing	obsolete negative regulation of adrenergic receptor signaling pathway involved in positive regulation of heart rate	OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of adrenergic receptor signaling pathway involved in positive regulation of heart rate.	tmpzr1t_l9r_go_relaxed.owl	downregulation of adrenergic receptor signalling pathway involved in positive regulation of heart rate|inhibition of If activation by beta-adrenergic receptor signaling pathway|negative regulation of If activation by beta-adrenergic receptor signaling pathway|negative regulation of activation of funny current by beta-adrenergic receptor signaling pathway|down-regulation of adrenergic receptor signaling pathway involved in positive regulation of heart rate|negative regulation of Gs-coupled adrenergic receptor signaling pathway involved in positive regulation of heart rate|downregulation of Gs-coupled adrenergic receptor signaling pathway involved in positive regulation of heart rate|inhibition of beta adrenergic receptor signaling pathway involved in positive regulation of heart rate|negative regulation of beta adrenergic receptor signaling pathway involved in positive regulation of heart rate|downregulation of If activation by beta-adrenergic receptor signaling pathway|negative regulation of adrenergic receptor signalling pathway involved in positive regulation of heart rate|down regulation of adenylate cyclase-activating cardiac adrenergic receptor signaling pathway|down regulation of adrenergic receptor signaling pathway involved in positive regulation of heart rate|downregulation of beta adrenergic receptor signaling pathway involved in positive regulation of heart rate|down regulation of beta adrenergic receptor signaling pathway involved in positive regulation of heart rate|down-regulation of Gs-coupled adrenergic receptor signaling pathway involved in positive regulation of heart rate|down regulation of Gs-coupled adrenergic receptor signaling pathway involved in positive regulation of heart rate|down-regulation of adenylate cyclase-activating cardiac adrenergic receptor signaling pathway|downregulation of activation of funny current by beta-adrenergic receptor signaling pathway|downregulation of adrenergic receptor signaling pathway involved in positive regulation of heart rate|down-regulation of beta adrenergic receptor signaling pathway involved in positive regulation of heart rate|down regulation of activation of funny current by beta-adrenergic receptor signaling pathway|negative regulation of adenylate cyclase-activating cardiac adrenergic receptor signaling pathway|down-regulation of adrenergic receptor signalling pathway involved in positive regulation of heart rate|inhibition of adrenergic receptor signalling pathway involved in positive regulation of heart rate|inhibition of Gs-coupled adrenergic receptor signaling pathway involved in positive regulation of heart rate|down regulation of If activation by beta-adrenergic receptor signaling pathway|inhibition of adenylate cyclase-activating cardiac adrenergic receptor signaling pathway|downregulation of adenylate cyclase-activating cardiac adrenergic receptor signaling pathway|down-regulation of If activation by beta-adrenergic receptor signaling pathway|inhibition of activation of funny current by beta-adrenergic receptor signaling pathway|inhibition of adrenergic receptor signaling pathway involved in positive regulation of heart rate|down-regulation of activation of funny current by beta-adrenergic receptor signaling pathway|down regulation of adrenergic receptor signalling pathway involved in positive regulation of heart rate	https://github.com/geneontology/go-ontology/issues/14733				This term was obsoleted because it is not precise enough. We must specify if the ACA-activating or ACA inhibiting pathway is the target of the regulation.		rl	2014-08-04T11:54:00Z		True			biological_process											owl:Class	
GO:0042993	biolink:NamedThing	obsolete positive regulation of transcription factor import into nucleus	OBSOLETE. Any process that activates or increases the frequency, rate or extent of the movement of a transcription factor from the cytoplasm to the nucleus.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of transcription factor transport from cytoplasm to nucleus|up regulation of transcription factor import into nucleus|positive regulation of transcription factor import into cell nucleus|upregulation of transcription factor import into nucleus|stimulation of transcription factor import into nucleus|positive regulation of transcription factor-nucleus import|up-regulation of transcription factor import into nucleus|activation of transcription factor import into nucleus					The reason for obsoletion is that there is no distinct pathway to import transcription factors into the nucleus.	GO:0042307				True			biological_process											owl:Class	
GO:0001304	biolink:NamedThing	obsolete progressive alteration of chromatin involved in replicative cell aging	OBSOLETE. A process that results in changes in chromatin structure contributing to replicative cell aging.	tmpzr1t_l9r_go_relaxed.owl	progressive alteration of chromatin during replicative cell ageing|progressive alteration of chromatin during replicative cell aging	https://github.com/geneontology/go-ontology/issues/20007				This term was obsoleted because it represents an assay, not a true biological process.					True			biological_process											owl:Class	
GO:0006341	biolink:NamedThing	obsolete chromatin insulator sequence binding	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	chromatin insulator sequence binding			GO:0043035		This term was made obsolete because it represents a molecular function and not a biological process.					True			biological_process											owl:Class	
GO:0003803	biolink:NamedThing	obsolete coagulation factor IXa activity	OBSOLETE. Catalysis of the selective cleavage of the Arg-Ile bond in factor X to form factor Xa.	tmpzr1t_l9r_go_relaxed.owl	blood coagulation factor IX activity|blood-coagulation factor IXa|activated christmas factor|blood platelet cofactor II|autoprothrombin II|activated blood coagulation factor XI|Christmas factor activity|coagulation factor IXa activity|activated blood-coagulation factor IX			GO:0004252		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:1905545	biolink:NamedThing	obsolete negative regulation of regulation of ferrichrome biosynthetic process by negative regulation of transcription from RNA polymerase II promoter in response to iron	OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of regulation of ferrichrome biosynthetic process by negative regulation of transcription from RNA polymerase II promoter in response to iron.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of regulation of ferrichrome biosynthesis by negative regulation of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome biosynthetic process by negative regulation of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome biosynthetic process, peptide modification by negative regulation of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome synthesis by down regulation of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome biosynthetic process, peptide modification by downregulation of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome biosynthetic process, peptide modification by negative regulation of transcription from Pol II promoter in response to iron|downregulation of regulation of ferrichrome biosynthesis by inhibition of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome synthesis by downregulation of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome biosynthesis by down-regulation of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome biosynthetic process by negative regulation of transcription from Pol II promoter in response to iron|down-regulation of regulation of ferrichrome biosynthesis by down regulation of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome biosynthesis by negative regulation of transcription from Pol II promoter in response to iron|downregulation of regulation of ferrichrome formation by inhibition of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome biosynthetic process, peptide modification by negative regulation of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome biosynthesis by down regulation of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome biosynthetic process by negative regulation of transcription from Pol II promoter in response to iron|down regulation of regulation of ferrichrome biosynthetic process, peptide modification by down regulation of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome synthesis by down-regulation of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome biosynthetic process, peptide formation by down regulation of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome anabolism by negative regulation of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome biosynthetic process, peptide formation by negative regulation of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome synthesis by down-regulation of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome synthesis by down regulation of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome biosynthetic process by down-regulation of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome biosynthesis by inhibition of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome formation by inhibition of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome formation by inhibition of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome biosynthesis by negative regulation of transcription from Pol II promoter in response to iron|negative regulation of regulation of ferrichrome biosynthetic process, peptide formation by inhibition of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome formation by down regulation of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome formation by downregulation of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome formation by downregulation of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome biosynthetic process, peptide formation by downregulation of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome synthesis by downregulation of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome biosynthetic process by down regulation of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome anabolism by negative regulation of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome formation by negative regulation of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome anabolism by negative regulation of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome biosynthesis by downregulation of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome formation by down-regulation of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome synthesis by down regulation of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome biosynthetic process by down-regulation of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome biosynthetic process, peptide formation by negative regulation of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome synthesis by negative regulation of transcription from Pol II promoter in response to iron|inhibition of regulation of ferrichrome biosynthetic process by inhibition of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome biosynthetic process, peptide formation by inhibition of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome anabolism by down regulation of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome synthesis by negative regulation of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome synthesis by inhibition of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome anabolism by negative regulation of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome synthesis by negative regulation of transcription from Pol II promoter in response to iron|down-regulation of regulation of ferrichrome biosynthetic process, peptide modification by inhibition of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome formation by negative regulation of transcription from Pol II promoter in response to iron|down-regulation of regulation of ferrichrome biosynthesis by downregulation of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome biosynthetic process by downregulation of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome biosynthetic process, peptide formation by negative regulation of transcription from Pol II promoter in response to iron|inhibition of regulation of ferrichrome biosynthetic process, peptide modification by down-regulation of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome biosynthesis by negative regulation of transcription from Pol II promoter in response to iron|negative regulation of regulation of ferrichrome synthesis by inhibition of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome anabolism by inhibition of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome biosynthetic process by negative regulation of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome biosynthetic process, peptide modification by negative regulation of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome formation by negative regulation of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome biosynthetic process, peptide formation by downregulation of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome biosynthesis by down-regulation of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome anabolism by negative regulation of transcription from Pol II promoter in response to iron|downregulation of regulation of ferrichrome formation by negative regulation of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome biosynthetic process, peptide formation by negative regulation of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome biosynthetic process, peptide modification by negative regulation of transcription from Pol II promoter in response to iron|down regulation of regulation of ferrichrome biosynthetic process, peptide formation by down regulation of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome biosynthetic process, peptide modification by down-regulation of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome synthesis by negative regulation of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome biosynthetic process by negative regulation of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome biosynthesis by negative regulation of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome synthesis by inhibition of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome anabolism by down-regulation of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome synthesis by negative regulation of transcription from Pol II promoter in response to iron|inhibition of regulation of ferrichrome anabolism by down regulation of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome biosynthetic process, peptide modification by inhibition of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome synthesis by downregulation of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome biosynthetic process, peptide modification by downregulation of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome formation by negative regulation of transcription from Pol II promoter in response to iron|inhibition of regulation of ferrichrome biosynthesis by negative regulation of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome biosynthetic process, peptide formation by down-regulation of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome synthesis by down-regulation of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome anabolism by inhibition of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome biosynthesis by negative regulation of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome biosynthesis by downregulation of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome biosynthetic process, peptide formation by down-regulation of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome biosynthesis by down-regulation of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome synthesis by negative regulation of transcription from Pol II promoter in response to iron|down-regulation of regulation of ferrichrome biosynthetic process by downregulation of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome formation by negative regulation of transcription from Pol II promoter in response to iron|negative regulation of regulation of ferrichrome anabolism by down-regulation of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome formation by down regulation of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome biosynthetic process, peptide formation by negative regulation of transcription from Pol II promoter in response to iron|inhibition of regulation of ferrichrome anabolism by down-regulation of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome formation by down regulation of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome formation by negative regulation of transcription from Pol II promoter in response to iron|down-regulation of regulation of ferrichrome anabolism by negative regulation of transcription from Pol II promoter in response to iron|downregulation of regulation of ferrichrome synthesis by inhibition of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome biosynthesis by negative regulation of transcription from Pol II promoter in response to iron|down regulation of regulation of ferrichrome anabolism by inhibition of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome biosynthetic process by downregulation of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome biosynthesis by negative regulation of transcription from Pol II promoter in response to iron|down-regulation of regulation of ferrichrome formation by negative regulation of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome biosynthetic process, peptide modification by downregulation of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome biosynthetic process by down-regulation of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome formation by downregulation of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome biosynthetic process, peptide modification by down regulation of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome biosynthetic process, peptide modification by negative regulation of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome biosynthetic process, peptide formation by negative regulation of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome biosynthetic process by downregulation of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome biosynthesis by down regulation of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome anabolism by down-regulation of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome biosynthesis by down-regulation of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome biosynthetic process by down regulation of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome formation by inhibition of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome biosynthetic process by down regulation of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome anabolism by downregulation of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome anabolism by inhibition of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome biosynthesis by downregulation of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome biosynthetic process, peptide formation by downregulation of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome synthesis by down-regulation of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome biosynthetic process, peptide formation by down-regulation of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome synthesis by negative regulation of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome biosynthetic process by inhibition of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome biosynthetic process, peptide modification by down-regulation of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome biosynthetic process by inhibition of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome formation by negative regulation of transcription from Pol II promoter in response to iron|down-regulation of regulation of ferrichrome biosynthetic process, peptide formation by down-regulation of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome biosynthetic process, peptide formation by down-regulation of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome formation by down-regulation of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome biosynthetic process, peptide modification by down regulation of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome biosynthetic process by negative regulation of transcription from Pol II promoter in response to iron|negative regulation of regulation of ferrichrome biosynthesis by downregulation of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome biosynthetic process, peptide formation by inhibition of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome anabolism by down regulation of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome biosynthetic process, peptide formation by negative regulation of transcription from Pol II promoter in response to iron|down-regulation of regulation of ferrichrome biosynthetic process, peptide formation by down regulation of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome biosynthetic process, peptide modification by inhibition of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome synthesis by inhibition of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome biosynthetic process by negative regulation of transcription from Pol II promoter in response to iron|inhibition of regulation of ferrichrome formation by negative regulation of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome biosynthetic process by inhibition of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome anabolism by negative regulation of transcription from Pol II promoter in response to iron|down regulation of regulation of ferrichrome anabolism by negative regulation of transcription from Pol II promoter in response to iron|down-regulation of regulation of ferrichrome anabolism by negative regulation of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome biosynthetic process, peptide formation by downregulation of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome biosynthetic process by downregulation of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome biosynthetic process, peptide formation by down regulation of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome biosynthetic process by negative regulation of transcription from Pol II promoter in response to iron|downregulation of regulation of ferrichrome biosynthetic process, peptide formation by inhibition of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome biosynthetic process by inhibition of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome synthesis by down regulation of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome biosynthetic process, peptide modification by negative regulation of transcription from Pol II promoter in response to iron|downregulation of regulation of ferrichrome biosynthetic process, peptide modification by inhibition of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome biosynthesis by inhibition of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome biosynthesis by inhibition of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome formation by downregulation of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome formation by inhibition of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome biosynthetic process by down-regulation of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome biosynthesis by negative regulation of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome biosynthetic process, peptide modification by negative regulation of transcription from Pol II promoter in response to iron|down regulation of regulation of ferrichrome biosynthesis by down regulation of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome formation by down-regulation of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome biosynthetic process, peptide formation by inhibition of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome biosynthetic process by down regulation of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome biosynthetic process, peptide modification by down-regulation of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome biosynthetic process, peptide modification by inhibition of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome biosynthetic process, peptide formation by negative regulation of transcription from Pol II promoter in response to iron|downregulation of regulation of ferrichrome synthesis by down regulation of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome synthesis by down-regulation of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome biosynthetic process, peptide formation by negative regulation of transcription from Pol II promoter in response to iron|down-regulation of regulation of ferrichrome synthesis by negative regulation of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome biosynthetic process, peptide formation by downregulation of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome anabolism by down regulation of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome synthesis by downregulation of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome biosynthetic process, peptide modification by downregulation of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome biosynthetic process, peptide modification by downregulation of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome anabolism by downregulation of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome synthesis by negative regulation of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome formation by down-regulation of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome synthesis by negative regulation of transcription from Pol II promoter in response to iron|inhibition of regulation of ferrichrome anabolism by downregulation of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome anabolism by downregulation of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome biosynthetic process by down-regulation of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome formation by downregulation of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome biosynthetic process, peptide formation by negative regulation of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome biosynthetic process, peptide modification by down regulation of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome biosynthesis by inhibition of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome biosynthesis by down regulation of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome formation by down-regulation of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome anabolism by inhibition of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome biosynthetic process by down regulation of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome synthesis by downregulation of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome biosynthetic process, peptide formation by down regulation of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome anabolism by downregulation of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome biosynthetic process, peptide modification by down-regulation of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome biosynthetic process, peptide modification by down regulation of transcription from RNA polymerase II promoter in response to iron|down regulation of regulation of ferrichrome biosynthetic process, peptide modification by negative regulation of transcription from Pol II promoter in response to iron|down-regulation of regulation of ferrichrome biosynthetic process, peptide modification by negative regulation of transcription from RNA polymerase II promoter in response to iron|inhibition of regulation of ferrichrome formation by down regulation of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome anabolism by down-regulation of transcription from RNA polymerase II promoter in response to iron|down-regulation of regulation of ferrichrome biosynthesis by down-regulation of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome formation by down regulation of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome anabolism by down regulation of transcription from RNA polymerase II promoter in response to iron|downregulation of regulation of ferrichrome biosynthetic process by negative regulation of transcription from RNA polymerase II promoter in response to iron|negative regulation of regulation of ferrichrome anabolism by negative regulation of transcription from Pol II promoter in response to iron					This term was obsoleted at the TermGenie Gatekeeper stage.		al	2016-10-11T16:15:05Z		True			biological_process											owl:Class	
GO:0001524	biolink:NamedThing	obsolete globin	OBSOLETE. The colorless and basic protein moiety of hemoglobin and myoglobins.	tmpzr1t_l9r_go_relaxed.owl	globin			GO:0005344		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0052017	biolink:NamedThing	obsolete catabolism by symbiont of host xylan	OBSOLETE. The chemical reactions and pathways performed by an organism resulting in the breakdown of xylan within the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	catabolism by organism of host xylan	https://github.com/geneontology/go-ontology/issues/21469				This term was obsoleted because it represents a molecular function.					True			biological_process											owl:Class	
GO:0044033	biolink:NamedThing	obsolete multi-organism metabolic process	OBSOLETE. A metabolic process - chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances - which involves more than one organism.	tmpzr1t_l9r_go_relaxed.owl	multi-organism metabolism|multi-organismal metabolic process|multi-organismal metabolism	https://github.com/geneontology/go-ontology/issues/19769				This term was obsoleted because there is no evidence that this process exists.					True			biological_process											owl:Class	
GO:0052331	biolink:NamedThing	obsolete hemolysis in other organism involved in symbiotic interaction	OBSOLETE. The cytolytic destruction of red blood cells, with the release of intracellular hemoglobin, in one organism by another, where two organisms are in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	hemolysin activity|haemolysis in other organism involved in symbiotic interaction|hemolysis of cells in other organism involved in symbiotic interaction|hemolysis by organism of RBCs in other organism during symbiotic interaction|hemolysis by organism of erythrocytes in other organism during symbiotic interaction|hemolysis by organism of red blood cells in other organism during symbiotic interaction|hemolysis of cells in other organism during symbiotic interaction					This term was obsoleted because it represents an unnecessary grouping class.					True			biological_process											owl:Class	
GO:0042064	biolink:NamedThing	obsolete cell adhesion receptor regulator activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	cell adhesion receptor regulator activity					This term was made obsolete because it represents a gene product.	GO:0030155|GO:0005102				True			molecular_function											owl:Class	
GO:0048196	biolink:NamedThing	obsolete plant extracellular matrix	OBSOLETE. The matrix external to the plant plasma membrane, composed of the cell wall and middle lamella.	tmpzr1t_l9r_go_relaxed.owl	plant extracellular matrix|middle lamella-containing extracellular matrix					Note that this term does not have 'extracellular region ; GO:0005576' as a parent because in plants the extracellular matrix is considered part of the cell.					True			cellular_component											owl:Class	
GO:0071431	biolink:NamedThing	obsolete tRNA-containing ribonucleoprotein complex export from nucleus	OBSOLETE. The directed movement of a ribonucleoprotein complex that contains transfer RNA from the nucleus to the cytoplasm.	tmpzr1t_l9r_go_relaxed.owl	tRNA-containing ribonucleoprotein complex transport from nucleus to cytoplasm|tRNA-containing ribonucleoprotein complex export from cell nucleus|tRNA-containing ribonucleoprotein complex nucleus export|tRNA-containing RNP export from nucleus	https://github.com/geneontology/go-ontology/issues/22246				This term has been obsoleted because it represents the transport of a carrier bound to its substrate.	GO:0051168	mah	2009-12-16T10:27:03Z		True			biological_process											owl:Class	
GO:0004254	biolink:NamedThing	obsolete acylaminoacyl-peptidase activity	OBSOLETE. Catalysis of the reaction: acylaminoacyl-peptide + H2O = acylamino acid + peptide.	tmpzr1t_l9r_go_relaxed.owl	N-acylpeptide hydrolase activity|acylamino-acid-releasing enzyme activity|acylaminoacyl-peptidase activity|alpha-N-acylpeptide hydrolase activity|N-formylmethionine (fMet) aminopeptidase activity			GO:0004252							True			molecular_function											owl:Class	
GO:0003808	biolink:NamedThing	obsolete protein C (activated) activity	OBSOLETE. Catalysis of the degradation of blood coagulation factors Va and VIIIa.	tmpzr1t_l9r_go_relaxed.owl	GSAPC|protein C (activated) activity|activated protein C|activated blood coagulation factor XIV activity|blood-coagulation factor XIVa|autoprothrombin II-A|protein Ca|autoprothrombin IIA activity			GO:0004252		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0052500	biolink:NamedThing	obsolete positive regulation by organism of symbiont apoptosis	OBSOLETE. Any process by which an organism activates, maintains or increases the frequency, rate or extent of programmed cell death in the symbiont, where programmed cell death proceeds by apoptosis. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	positive regulation by organism of symbiont apoptosis|positive regulation by organism of symbiont apoptotic programmed cell death					This term was made obsolete because it does not represent a real biological process.					True			biological_process											owl:Class	
GO:0008548	biolink:NamedThing	obsolete signal-recognition-particle GTPase activity	OBSOLETE. Catalysis of the reaction: GTP + H2O = GDP + phosphate. Activity is associated with the signal-recognition particle, a protein and RNA-containing structure involved in endoplasmic reticulum-associated protein synthesis.	tmpzr1t_l9r_go_relaxed.owl	signal-recognition-particle GTPase activity					This term was made obsolete because it represents a gene product.	GO:0005786|GO:0003924				True			molecular_function											owl:Class	
GO:0060991	biolink:NamedThing	obsolete lipid tube assembly involved in cytokinesis	OBSOLETE. The aggregation, arrangement and bonding together of a set of macromolecules to form a macromolecular complex that contains a tube of lipid surrounded by a protein coat involved in cytokinesis.	tmpzr1t_l9r_go_relaxed.owl	lipid tubulation involved in cytokinesis|lipid tube assembly involved in cytokinesis					This term was made obsolete because there is no evidence the process exists.		dph	2010-01-11T02:22:25Z		True			biological_process											owl:Class	
GO:0030530	biolink:NamedThing	obsolete heterogeneous nuclear ribonucleoprotein complex	OBSOLETE. Particulate complex of heterogeneous nuclear RNA (hnRNA; a heterogeneous mixture of RNA molecules of high Mr with a rapid turnover rate that occurs in cell nuclei during protein synthesis; it is the form of RNA synthesized in eukaryotes by RNA polymerase II, that which is translated into protein) with protein, which is cell-specific and heterogeneous. The protein component may play a role in the processing of the hnRNA to mRNA.	tmpzr1t_l9r_go_relaxed.owl	heterogeneous nuclear ribonucleoprotein complex|heterogeneous nuclear ribonucleoprotein|hnRNP				Wikipedia:Heterogeneous_ribonucleoprotein_particle	This term was made because heterogeneous nuclear ribonucleoprotein is an experimental construct and does not correspond cleanly to a functional cellular entity.	GO:1990904|GO:0005681				True			cellular_component											owl:Class	
GO:0052407	biolink:NamedThing	obsolete metabolism by organism of carbohydrate in other organism involved in symbiotic interaction	OBSOLETE. The chemical reactions and pathways performed by an organism involving carbohydrates within a second organism, where the two organisms are in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	metabolism by organism of carbohydrate in other organism during symbiotic interaction	https://github.com/geneontology/go-ontology/issues/21396				This term was obsoleted because it represents an unnecessary grouping class.					True			biological_process											owl:Class	
GO:0051195	biolink:NamedThing	obsolete negative regulation of cofactor metabolic process	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving a cofactor.	tmpzr1t_l9r_go_relaxed.owl	downregulation of cofactor metabolic process|down-regulation of cofactor metabolic process|down regulation of cofactor metabolic process|inhibition of cofactor metabolic process|negative regulation of cofactor metabolism					1. Making inferences in GO about compounds based on the cofactor role curated by ChEBI creates relationships that are not always true which violates ontological principles for GO; therefore we will cease making these inferences. 2. It is not meaningful to group metabolic processes that are not all chemically related by the fact that they may be used as a cofactor.					True			biological_process											owl:Class	
GO:0042141	biolink:NamedThing	obsolete mating pheromone exporter	OBSOLETE. Exports diffusible peptide signals that are responsible for binding to other cells and triggering a series of responses to facilitate mating.	tmpzr1t_l9r_go_relaxed.owl	mating pheromone exporter					This term was made obsolete because it is too gene product specific.	GO:0042626|GO:0043190				True			molecular_function											owl:Class	
GO:0045474	biolink:NamedThing	obsolete response to ether (sensu Insecta)	OBSOLETE. A change in state or activity of an insect (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ether stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to ether (sensu Insecta)					This term was made obsolete because there is no clear difference between the sensu Insecta term and the generic term.	GO:0048150				True			biological_process											owl:Class	
GO:0000115	biolink:NamedThing	obsolete regulation of transcription involved in S phase of mitotic cell cycle	OBSOLETE. A cell cycle process that regulates transcription such that the target genes are transcribed as part of the S phase of the mitotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl	S-phase-specific transcription in mitotic cell cycle|regulation of transcription from RNA polymerase II promoter during S-phase of mitotic cell cycle|regulation of transcription involved in S-phase of mitotic cell cycle|regulation of transcription involved in S phase of mitotic cell cycle|S-specific transcription in mitotic cell cycle					This term was made obsolete because it is unclear exactly what it means. It could mean either 'regulation of transcription during phase X' or 'regulation of transition between phase X and phase Y'.	GO:0000083|GO:0006357				True			biological_process											owl:Class	
GO:0006852	biolink:NamedThing	obsolete mitochondrial sodium/calcium ion exchange	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	mitochondrial sodium/calcium ion exchange|mitochondrial sodium/calcium exchange					This term was made obsolete because it represents function rather than a process.	GO:0006814|GO:0006839|GO:0005432|GO:0006816				True			biological_process											owl:Class	
GO:0045021	biolink:NamedThing	obsolete error-free DNA repair	OBSOLETE. DNA repair pathways that do not increase the mutation rate above spontaneous background levels, e.g. excision and recombination pathways.	tmpzr1t_l9r_go_relaxed.owl	error-free DNA repair					This term was made obsolete because 'error-free' does not correspond to a repair mechanism, and the term has been superseded by more specific terms.	GO:0042275|GO:0070987				True			biological_process											owl:Class	
GO:0051115	biolink:NamedThing	obsolete enzyme active site formation via 1'-(phospho-5'-uridine)-L-histidine	OBSOLETE. The transient uridylylation of peptidyl-histidine to form 1'-(phospho-5'-uridine)-L-histidine (otherwise known as tau-UMP-histidine, tele-UMP-histidine).	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/15594			RESID:AA0372	This term was obsoleted because it represents a reaction intermediate, not a biological process, see PMID:8794735.	GO:0017103				True			biological_process											owl:Class	
GO:0016536	biolink:NamedThing	obsolete cyclin-dependent protein kinase 5 activator regulator activity	OBSOLETE. Modulation of the activity of cyclin-dependent protein kinase 5 activator.	tmpzr1t_l9r_go_relaxed.owl	cyclin-dependent protein kinase 5 activator, intrinsic regulator activity|cyclin-dependent protein kinase 5 activator regulator activity					This term was made obsolete because it refers to a specific gene product.					True			molecular_function											owl:Class	
GO:0005301	biolink:NamedThing	obsolete valine/tyrosine/tryptophan permease activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	valine/tyrosine/tryptophan permease activity|hydrogen/valine-tyrosine-tryptophan transporter					This term was made obsolete because it represents a multifunctional gene product.	GO:0015196|GO:0005304|GO:0005302|GO:0022857				True			molecular_function											owl:Class	
GO:0003717	biolink:NamedThing	obsolete RNA polymerase II transcription termination factor activity	OBSOLETE. Any activity that brings about termination of transcription by RNA polymerase II.	tmpzr1t_l9r_go_relaxed.owl	Pol II transcription termination factor activity|RNA polymerase II transcription termination factor activity					This term was obsoleted because it is essentially identical to a Process term (specifically the Biological Process term which has been selected as a term to consider for reannotation), i.e. it is defined only in terms of the process it acts in and it does NOT convey any information about the molecular nature of the function or whether the function is based on binding DNA, on interacting with other proteins, or some other mechanism. To transfer all annotations without review, the BP term indicated is considered to be equivalent and thus the only appropriate destination for all annotations. To reannotate to a MF term, you will probably need to revisit the original literature or other primary data because this "MF" term was not defined in terms of mechanism of action and there are multiple possibilities in the revised MF structure. In reannotation, please also consider descendent terms of the suggested MF terms as a more specific term may be more appropriate than the MF terms indicated. Please be aware that you may wish to request a new term if the mechanism of action of this gene product is not yet represented or if you are annotating for an RNAP different than one for which there is a specific suggested term. Also note that if there is no information about how the gene product acts, it may be appropriate to annotate to the root term for molecular_function.	GO:0006369				True			molecular_function											owl:Class	
GO:0001690	biolink:NamedThing	obsolete cytoplasmic dynein light chain	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	cytoplasmic dynein light chain			GO:0005868		This term was made obsolete because it represents a single gene product and not a complex.					True			cellular_component											owl:Class	
GO:0004211	biolink:NamedThing	obsolete caspase-9 activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	caspase-9 activity			GO:0004197		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:1900061	biolink:NamedThing	obsolete positive regulation of transcription from RNA polymerase II promoter involved in calcium-mediated signaling	OBSOLETE. Any positive regulation of transcription from RNA polymerase II promoter that is involved in calcium-mediated signaling.	tmpzr1t_l9r_go_relaxed.owl	upregulation of transcription from RNA polymerase II promoter of calcium-mediated signalling|positive regulation of gene-specific transcription from RNA polymerase II promoter of calcium-mediated signaling|upregulation of global transcription from RNA polymerase II promoter of calcium signaling|positive regulation of transcription from RNA polymerase II promoter of calcium-mediated signaling|stimulation of global transcription from RNA polymerase II promoter of calcium-mediated signaling|activation of global transcription from RNA polymerase II promoter of calcium-mediated signaling|stimulation of transcription from RNA polymerase II promoter of calcium-mediated signaling|positive regulation of transcription from RNA polymerase II promoter of calcium-mediated signalling|stimulation of transcription from RNA polymerase II promoter of calcium signalling|up regulation of transcription from RNA polymerase II promoter of calcium signalling|activation of transcription from RNA polymerase II promoter of calcium-mediated signalling|up-regulation of global transcription from RNA polymerase II promoter of calcium-mediated signalling|up regulation of global transcription from RNA polymerase II promoter of calcium-mediated signaling|activation of global transcription from RNA polymerase II promoter of calcium-mediated signalling|up regulation of global transcription from RNA polymerase II promoter of calcium ion signaling|activation of transcription from RNA polymerase II promoter of calcium signalling|stimulation of global transcription from RNA polymerase II promoter of calcium-mediated signalling|up-regulation of global transcription from RNA polymerase II promoter of calcium signaling|stimulation of transcription from RNA polymerase II promoter of calcium signaling|up-regulation of transcription from RNA polymerase II promoter of calcium-mediated signaling|up-regulation of global transcription from RNA polymerase II promoter of calcium signalling|up-regulation of transcription from RNA polymerase II promoter of calcium ion signaling|positive regulation of global transcription from Pol II promoter of calcium-mediated signaling|positive regulation of global transcription from Pol II promoter of calcium-mediated signalling|positive regulation of transcription from RNA polymerase II promoter involved in calcium-mediated signaling|positive regulation of gene-specific transcription from RNA polymerase II promoter of calcium signaling|up regulation of global transcription from RNA polymerase II promoter of calcium signalling|stimulation of transcription from RNA polymerase II promoter of calcium ion signaling|positive regulation of transcription from Pol II promoter of calcium-mediated signalling|upregulation of global transcription from RNA polymerase II promoter of calcium-mediated signalling|upregulation of transcription from RNA polymerase II promoter of calcium-mediated signaling|positive regulation of transcription from RNA polymerase II promoter of calcium ion signaling|positive regulation of global transcription from Pol II promoter of calcium ion signaling|activation of global transcription from RNA polymerase II promoter of calcium signalling|up-regulation of global transcription from RNA polymerase II promoter of calcium-mediated signaling|positive regulation of global transcription from Pol II promoter of calcium signaling|positive regulation of transcription from RNA polymerase II promoter of calcium signalling|positive regulation of transcription from RNA polymerase II promoter of calcium signaling|up-regulation of transcription from RNA polymerase II promoter of calcium-mediated signalling|positive regulation of gene-specific transcription from RNA polymerase II promoter of calcium signalling|positive regulation of gene-specific transcription from RNA polymerase II promoter of calcium ion signaling|upregulation of global transcription from RNA polymerase II promoter of calcium-mediated signaling|positive regulation of transcription from Pol II promoter of calcium signaling|positive regulation of global transcription from Pol II promoter of calcium signalling|upregulation of transcription from RNA polymerase II promoter of calcium signaling|upregulation of transcription from RNA polymerase II promoter of calcium signalling|up regulation of transcription from RNA polymerase II promoter of calcium-mediated signaling|activation of transcription from RNA polymerase II promoter of calcium signaling|positive regulation of transcription from Pol II promoter of calcium-mediated signaling|up regulation of transcription from RNA polymerase II promoter of calcium ion signaling|activation of global transcription from RNA polymerase II promoter of calcium signaling|positive regulation of gene-specific transcription from RNA polymerase II promoter of calcium-mediated signalling|up regulation of global transcription from RNA polymerase II promoter of calcium-mediated signalling|stimulation of global transcription from RNA polymerase II promoter of calcium signalling|activation of global transcription from RNA polymerase II promoter of calcium ion signaling|stimulation of global transcription from RNA polymerase II promoter of calcium signaling|stimulation of transcription from RNA polymerase II promoter of calcium-mediated signalling|activation of transcription from RNA polymerase II promoter of calcium-mediated signaling|upregulation of global transcription from RNA polymerase II promoter of calcium signalling|up-regulation of global transcription from RNA polymerase II promoter of calcium ion signaling|up-regulation of transcription from RNA polymerase II promoter of calcium signalling|up regulation of global transcription from RNA polymerase II promoter of calcium signaling|up-regulation of transcription from RNA polymerase II promoter of calcium signaling|positive regulation of transcription from Pol II promoter of calcium signalling|activation of transcription from RNA polymerase II promoter of calcium ion signaling|upregulation of transcription from RNA polymerase II promoter of calcium ion signaling|upregulation of global transcription from RNA polymerase II promoter of calcium ion signaling|stimulation of global transcription from RNA polymerase II promoter of calcium ion signaling|positive regulation of transcription from Pol II promoter of calcium ion signaling|up regulation of transcription from RNA polymerase II promoter of calcium-mediated signalling|up regulation of transcription from RNA polymerase II promoter of calcium signaling					This term was made obsolete because it represents a GO-CAM model.	GO:0045944|GO:0019722	dph	2012-01-26T01:42:53Z		True			biological_process											owl:Class	
GO:0052461	biolink:NamedThing	obsolete modulation by organism of pathogen-associated molecular pattern-induced symbiont innate immunity	OBSOLETE. This term was not defined before being made obsolete.	tmpzr1t_l9r_go_relaxed.owl	modulation by organism of pathogen-associated molecular pattern-induced symbiont innate immunity					This term was made obsolete because it does not represent a real biological process.					True			biological_process											owl:Class	
GO:0000230	biolink:NamedThing	obsolete nuclear mitotic chromosome	OBSOLETE. A chromosome found in the nucleus during mitosis.	tmpzr1t_l9r_go_relaxed.owl	nuclear mitotic chromosome					This term was made obsolete because it is based on a temporal division of the cell cycle.	GO:0000794				True			cellular_component											owl:Class	
GO:0052517	biolink:NamedThing	obsolete positive regulation by organism of symbiont non-apoptotic programmed cell death	OBSOLETE. Any process by which an organism activates, maintains or increases the frequency, rate or extent of programmed cell death in the symbiont, where programmed cell death proceeds by a non-apoptotic pathway. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	positive regulation by organism of symbiont non-apoptotic programmed cell death					This term was made obsolete because it does not represent a real biological process.					True			biological_process											owl:Class	
GO:1990371	biolink:NamedThing	obsolete process resulting in tolerance to phenol	OBSOLETE. A response that results in a state of tolerance to phenol.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it does not represent a clear process.		tt	2014-04-23T22:32:48Z		True			biological_process											owl:Class	
GO:1990981	biolink:NamedThing	obsolete regulation of protein localization to cell division site involved in cell separation after cytokinesis	OBSOLETE. A regulation of protein localization to cell division site involved in cell separation after cytokinesis.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted at the TermGenie Gatekeeper stage.		vw	2016-08-21T19:43:21Z		True			biological_process											owl:Class	
GO:0016357	biolink:NamedThing	obsolete pyrethroid susceptibility/resistance	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	pyrethroid susceptibility/resistance			GO:0046684		This term was made obsolete because 'susceptibility/resistance' implies a phenotype rather than a biological process.					True			biological_process											owl:Class	
GO:0004244	biolink:NamedThing	obsolete mitochondrial inner membrane peptidase activity	OBSOLETE. Catalysis of the maturation of mitochondrial precursor proteins delivered to the intermembrane space.	tmpzr1t_l9r_go_relaxed.owl	IMP|mitochondrial inner membrane peptidase activity			GO:0004175		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0004261	biolink:NamedThing	obsolete cathepsin G activity	OBSOLETE. Catalysis of the hydrolysis of peptide bonds. Specificity similar to chymotrypsin C.	tmpzr1t_l9r_go_relaxed.owl	cathepsin G activity|neutral proteinase activity|chymotrypsin-like proteinase activity			GO:0004252		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0042315	biolink:NamedThing	obsolete cytosol nonspecific dipeptidase activity	OBSOLETE. Catalysis of the hydrolysis of dipeptides, preferentially hydrophobic dipeptides including prolyl amino acids.	tmpzr1t_l9r_go_relaxed.owl	glycyl-L-leucine hydrolase activity|N2-beta-alanylarginine dipeptidase activity|L-amino-acyl-L-amino-acid hydrolase activity|human cytosolic non-specific dipeptidase activity|prolylglycine dipeptidase activity|glycyl-leucine dipeptidase activity|Gly-Leu hydrolase activity|L-prolylglycine dipeptidase activity|peptidase A activity|iminodipeptidase activity|glycylleucine peptidase activity|glycyl-glycine dipeptidase activity|prolyl dipeptidase activity|diglycinase activity|cytosol nonspecific dipeptidase activity|Pro-X dipeptidase activity|non-specific dipeptidase activity|N(2)-beta-alanylarginine dipeptidase activity|glycylleucine hydrolase activity|glycyl-L-leucine dipeptidase activity|glycyl-L-leucine peptidase activity|glycylleucine dipeptide hydrolase activity|prolinase activity|cytosol non-specific dipeptidase activity			GO:0016805		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0007071	biolink:NamedThing	obsolete negative regulation of transcription from RNA polymerase III promoter during mitotic cell cycle	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of transcription from an RNA polymerase III promoter that occurs during the mitotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of transcription from RNA polymerase III promoter, mitotic|negative regulation of transcription from Pol III promoter during mitosis|down regulation of transcription from RNA polymerase III promoter during mitosis|down-regulation of transcription from RNA polymerase III promoter during mitosis|mitotic repression of transcription from Pol III promoter|downregulation of transcription from RNA polymerase III promoter during mitosis|inhibition of transcription from RNA polymerase III promoter during mitosis	https://github.com/geneontology/go-ontology/issues/14896				The reason for obsoletion is that 'during' should be captured using an annotation extension.	GO:0044772|GO:0016480				True			biological_process											owl:Class	
GO:0015997	biolink:NamedThing	obsolete ubiquinone biosynthetic process monooxygenase activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	ubiquinone formation monooxygenase activity|ubiquinone biosynthetic process monooxygenase activity|coenzyme Q biosynthesis monooxygenase activity|ubiquinone anabolism monooxygenase activity|coenzyme Q biosynthetic process monooxygenase activity|ubiquinone synthesis monooxygenase activity					This term was made obsolete because it incorporates biological process information.					True			molecular_function											owl:Class	
GO:0016676	biolink:NamedThing	obsolete oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor	OBSOLETE. Catalysis of an oxidation-reduction (redox) reaction in which a heme group acts as a hydrogen or electron donor and reduces oxygen.	tmpzr1t_l9r_go_relaxed.owl	oxidoreductase activity, acting on haem group of donors, oxygen as acceptor	https://github.com/geneontology/go-ontology/issues/20923			EC:1.9.3.-	This term was obsoleted because Enzyme Commission (EC) has rehoused all its descendant classes,  and this is now a grouping term with not children.					True			molecular_function											owl:Class	
GO:0071534	biolink:NamedThing	obsolete zf-TRAF domain-mediated complex assembly	OBSOLETE. A process of protein complex assembly in which the arrangement and bonding together of the set of components that form the protein complex is mediated by a TRAF-type zinc finger (zf-TRAF) domain interaction.	tmpzr1t_l9r_go_relaxed.owl	zinc finger TRAF-type domain-mediated complex assembly|zinc-finger-TRAF domain-mediated complex assembly|TRAF-type zinc finger domain-mediated complex assembly					This term was obsoleted because it represented a molecular function (binding), not a biological process.  The term represented a domain involved in protein-protein interactions, but no necessarily the process of assembling a complex.		mah	2010-01-08T02:40:50Z		True			biological_process											owl:Class	
GO:0075168	biolink:NamedThing	obsolete regulation of protein kinase-mediated signal transduction in response to host	OBSOLETE. Any process in which the symbiont organism modulates the frequency, rate or extent of its protein kinase-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	regulation of symbiont protein kinase-mediated signal transduction in response to host					This term was obsoleted because there is no evidence that this process exists.					True			biological_process											owl:Class	
GO:1900531	biolink:NamedThing	obsolete regulation of cell shape involved in cellular response to heat	OBSOLETE. Any regulation of cell shape that is involved in cellular response to heat.	tmpzr1t_l9r_go_relaxed.owl	regulation of cell shape of cellular response to heat|regulation of cell shape involved in cellular response to heat|regulation of cell shape of cellular response to heat stress					This term was obsoleted at the TermGenie Gatekeeper stage.		al	2012-05-08T01:51:00Z		True			biological_process											owl:Class	
GO:0045164	biolink:NamedThing	obsolete secretin (sensu Mammalia)	OBSOLETE. Secretin is a hormone that takes part in the digestion process. It also has effects on organs other than gastrointestinal tract.	tmpzr1t_l9r_go_relaxed.owl	secretin (sensu Mammalia)					This term was made obsolete because it represents a gene product rather than a molecular function.	GO:0046659				True			molecular_function											owl:Class	
GO:0033804	biolink:NamedThing	obsolete glycine/sarcosine N-methyltransferase activity	OBSOLETE. Catalysis of the reactions: S-adenosyl-L-methionine + glycine = S-adenosyl-L-homocysteine + sarcosine, and S-adenosyl-L-methionine + sarcosine = S-adenosyl-L-homocysteine + N,N-dimethylglycine.	tmpzr1t_l9r_go_relaxed.owl	glycine sarcosine N-methyltransferase activity|S-adenosyl-L-methionine:sarcosine N-methyltransferase activity|glycine-sarcosine methyltransferase activity|ApGSMT|GMT|glycine/sarcosine N-methyltransferase activity|GSMT					This term was made obsolete because it represents two reactions, and should be two separate terms.	GO:0017174|GO:0052730				True			molecular_function											owl:Class	
GO:1900043	biolink:NamedThing	obsolete leptin-mediated signaling pathway involved in negative regulation of appetite	OBSOLETE. Any leptin-mediated signaling pathway that is involved in negative regulation of appetite.	tmpzr1t_l9r_go_relaxed.owl	adipocytokine signaling pathway of appetite suppression|adipocytokine signaling pathway of down-regulation of appetite|leptin-mediated signaling pathway of negative regulation of hunger|leptin-mediated signaling pathway of appetite suppression|leptin-mediated signalling pathway of negative regulation of hunger|leptin-mediated signaling pathway of inhibition of appetite|adipocytokine signaling pathway of negative regulation of appetite|leptin-mediated signaling pathway of down regulation of appetite|adipocytokine signaling pathway of down regulation of appetite|leptin-mediated signalling pathway of downregulation of appetite|leptin-mediated signaling pathway of downregulation of appetite|leptin-mediated signaling pathway involved in negative regulation of appetite|leptin-mediated signalling pathway of appetite suppression|leptin-mediated signalling pathway of down-regulation of appetite|adipocytokine signaling pathway of downregulation of appetite|leptin-mediated signaling pathway of negative regulation of appetite|leptin-mediated signaling pathway of down-regulation of appetite|leptin-mediated signalling pathway of inhibition of appetite|leptin-mediated signalling pathway of down regulation of appetite|adipocytokine signaling pathway of negative regulation of hunger|leptin-mediated signalling pathway of negative regulation of appetite|adipocytokine signaling pathway of inhibition of appetite					This term was obsoleted at the TermGenie Gatekeeper stage.		vk	2012-01-19T11:10:22Z		True			biological_process											owl:Class	
GO:0042991	biolink:NamedThing	obsolete transcription factor import into nucleus	OBSOLETE. The directed movement of a transcription factor from the cytoplasm to the nucleus.	tmpzr1t_l9r_go_relaxed.owl	transcription factor import into cell nucleus|transcription factor transport from cytoplasm to nucleus|transcription factor-nucleus import					The reason for obsoletion is that there is no distinct pathway to import transcription factors into the nucleus.	GO:0006606				True			biological_process											owl:Class	
GO:0052503	biolink:NamedThing	obsolete positive regulation by organism of defense-related symbiont calcium-dependent protein kinase pathway	OBSOLETE. Any process by which an organism activates, maintains or increases the frequency, rate or extent of the symbiont calcium-dependent protein kinase pathway during the symbiont defense response. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of defense-related symbiont CDPK pathway by organism|positive regulation by organism of defense-related symbiont calcium-dependent protein kinase pathway					This term was made obsolete because it does not represent a real biological process.					True			biological_process											owl:Class	
GO:0060849	biolink:NamedThing	obsolete regulation of transcription involved in lymphatic endothelial cell fate commitment	OBSOLETE. Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the commitment of a venous endothelial cell to a lymphatic endothelial cell.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it represents a GO-CAM model.	GO:0060838|GO:0006357	dph	2009-08-12T11:19:14Z		True			biological_process											owl:Class	
GO:1900466	biolink:NamedThing	obsolete positive regulation of arginine biosynthetic process by positive regulation of transcription from RNA polymerase II promoter	OBSOLETE. Any process that activates or increases the frequency, rate or extent of arginine biosynthetic process by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter.	tmpzr1t_l9r_go_relaxed.owl	upregulation of arginine formation by positive regulation of transcription from RNA polymerase II promoter|positive regulation of arginine anabolism by positive regulation of transcription from RNA polymerase II promoter|activation of arginine biosynthesis by positive regulation of transcription from RNA polymerase II promoter|upregulation of arginine biosynthetic process by positive regulation of transcription from RNA polymerase II promoter|up regulation of arginine formation by positive regulation of transcription from RNA polymerase II promoter|activation of arginine biosynthetic process by positive regulation of transcription from RNA polymerase II promoter|activation of arginine formation by positive regulation of transcription from RNA polymerase II promoter|positive regulation of arginine synthesis by positive regulation of transcription from RNA polymerase II promoter|positive regulation of arginine biosynthesis by positive regulation of transcription from RNA polymerase II promoter|positive regulation of arginine formation by positive regulation of transcription from RNA polymerase II promoter|up regulation of arginine anabolism by positive regulation of transcription from RNA polymerase II promoter|up-regulation of arginine anabolism by positive regulation of transcription from RNA polymerase II promoter|upregulation of arginine anabolism by positive regulation of transcription from RNA polymerase II promoter|upregulation of arginine synthesis by positive regulation of transcription from RNA polymerase II promoter|up-regulation of arginine biosynthesis by positive regulation of transcription from RNA polymerase II promoter|activation of arginine synthesis by positive regulation of transcription from RNA polymerase II promoter|up regulation of arginine synthesis by positive regulation of transcription from RNA polymerase II promoter|up regulation of arginine biosynthetic process by positive regulation of transcription from RNA polymerase II promoter|up regulation of arginine biosynthesis by positive regulation of transcription from RNA polymerase II promoter|up-regulation of arginine biosynthetic process by positive regulation of transcription from RNA polymerase II promoter|up-regulation of arginine synthesis by positive regulation of transcription from RNA polymerase II promoter|activation of arginine anabolism by positive regulation of transcription from RNA polymerase II promoter|up-regulation of arginine formation by positive regulation of transcription from RNA polymerase II promoter|upregulation of arginine biosynthesis by positive regulation of transcription from RNA polymerase II promoter					This term was obsoleted because it represents a GO-CAM model.		dgf	2012-05-01T07:38:14Z		True			biological_process											owl:Class	
GO:0035955	biolink:NamedThing	obsolete negative regulation of dipeptide transport by negative regulation of transcription from RNA polymerase II promoter	OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of dipeptide transport by stopping, preventing or reducing the frequency, rate or extent of transcription from an RNA polymerase II promoter.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of dipeptide transport by inhibition of transcription from RNA polymerase II promoter|negative regulation of dipeptide transport by negative regulation of transcription from Pol II promoter|negative regulation of dipeptide transport by down-regulation of transcription from RNA polymerase II promoter|negative regulation of dipeptide transport by down regulation of transcription from RNA polymerase II promoter|negative regulation of dipeptide transport by downregulation of transcription from RNA polymerase II promoter					This term was obsoleted because it represents a GO-CAM model.		bf			True			biological_process											owl:Class	
GO:0035111	biolink:NamedThing	obsolete leg joint morphogenesis	OBSOLETE. The process in which the anatomical structures of a leg joint are generated and organized. The leg joint is a flexible region that separates the rigid sections of a leg to allow movement in a controlled manner. One example is the knee, which separates the leg tibia and femur.	tmpzr1t_l9r_go_relaxed.owl	leg joint morphogenesis					This term was made obsolete because leg is a mechano-functional grouping, and having both 'leg morphogenesis' and 'hindlimb morphogenesis' terms causes errors in querying.	GO:0036023|GO:0016348				True			biological_process											owl:Class	
GO:0048516	biolink:NamedThing	obsolete trichome initiation (sensu Magnoliophyta)	OBSOLETE. Processes causing the differentiation of an epidermal cell into a trichome cell; as in, but not restricted to, the flowering plants (Magnoliophyta, ncbi_taxonomy_id:3398).	tmpzr1t_l9r_go_relaxed.owl	trichome initiation (sensu Magnoliophyta)					This term was made obsolete because more appropriate terms were created.	GO:0048629				True			biological_process											owl:Class	
GO:0003791	biolink:NamedThing	obsolete membrane associated actin binding	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	membrane associated actin binding					This term was made obsolete because it contains both component and function information.	GO:0016020|GO:0003779				True			molecular_function											owl:Class	
GO:0031376	biolink:NamedThing	obsolete cytosolic type II fatty acid synthase complex	OBSOLETE. A fatty acid synthase complex in which each polypeptide chain catalyzes a single activity, located in the cytosol.	tmpzr1t_l9r_go_relaxed.owl	cytosolic type II fatty acid synthase complex|cytosolic type II FAS complex										True			cellular_component											owl:Class	
GO:0005181	biolink:NamedThing	obsolete glycopeptide hormone	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	glycopeptide hormone					This term was made obsolete because it describes a type of hormone rather than a molecular function.	GO:0005179				True			molecular_function											owl:Class	
GO:0003813	biolink:NamedThing	obsolete classical-complement-pathway C3/C5 convertase activity	OBSOLETE. Catalysis of the selective cleavage of Arg-Ser bond in complement component C3 alpha-chain to form C3a and C3b, and Arg bond in complement component C5 alpha-chain to form C5a and C5b.	tmpzr1t_l9r_go_relaxed.owl	complement C2 activity|C4b,2a,3b|C3 convertase activity|classical-complement-pathway C3/C5 convertase activity|C4b,2a|C5 convertase activity|complement C3 convertase activity|complement C42|C423|C42			GO:0004252		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0106180	biolink:NamedThing	obsolete translocase activty of hydrons	OBSOLETE. Catalysis of the translocation of hydrons (hydron being the general name for H+ in its natural abundance).	tmpzr1t_l9r_go_relaxed.owl					EC:7.1.-.-	This term was made obsolete because the concept of using the non-4 digit EC classes as parent terms for the transporter banch of the onotolgy was consided confusing.		hjd	2019-04-05T15:48:44Z		True			molecular_function											owl:Class	
GO:0106202	biolink:NamedThing	obsolete translocase activity acting on amino acids and peptides linked to a decarboxylation reaction	OBSOLETE. Catalysis of the translocation of amno acids and peptides linked to a decarboxylation reaction.	tmpzr1t_l9r_go_relaxed.owl					EC:7.4.4.-	This term was made obsolete because the concept of using the non-4 digit EC classes as parent terms for the transporter banch of the onotolgy was consided confusing.		hjd	2019-05-08T18:30:36Z		True			molecular_function											owl:Class	
GO:0001090	biolink:NamedThing	obsolete transcription factor activity, TFIIH-class binding	OBSOLETE. Binding to a basal RNA polymerase II transcription factor of the TFIIH class in order to modulate transcription. The transcription factor may or may not also interact selectively with DNA as well.	tmpzr1t_l9r_go_relaxed.owl	TFIIH-class binding transcription factor activity					This term was obsoleted because it represents two separate functions. The corresponding 'binding' term should be used in combination with a transcription regulator activity child.		krc	2010-10-28T02:28:01Z		True			molecular_function											owl:Class	
GO:0055061	biolink:NamedThing	obsolete di-, tri-valent inorganic anion homeostasis	OBSOLETE. Any process involved in the maintenance of an internal steady state of divalent or trivalent inorganic anions within an organism or cell.	tmpzr1t_l9r_go_relaxed.owl	di-, tri-valent inorganic anion homeostasis					This term was made obsolete because it has been split.	GO:0072506|GO:0072505				True			biological_process											owl:Class	
GO:0001686	biolink:NamedThing	obsolete axonemal dynein light chain	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	axonemal dynein light chain			GO:0005858		This term was made obsolete because it represents a single gene product and not a complex.					True			cellular_component											owl:Class	
GO:0052016	biolink:NamedThing	obsolete catabolism by symbiont of host glucan	OBSOLETE. The chemical reactions and pathways performed by an organism resulting in the breakdown of glucan molecules within the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	catabolism by organism of host glucan	https://github.com/geneontology/go-ontology/issues/21469				This term was obsoleted because it represents a molecular function.					True			biological_process											owl:Class	
GO:2000046	biolink:NamedThing	obsolete regulation of G2 phase of mitotic cell cycle	OBSOLETE. Any process that modulates the frequency, rate or extent of G2 phase of mitotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl	regulation of G2 phase of mitotic cell cycle					This term was made obsolete because we felt that phases themselves are not being regulated, it's rather the transitions between phases. If you are trying to make an annotation to x phase, it is likely that the correct process is 'regulation of x/y phase transiition.	GO:0010389	tb	2010-08-19T09:19:18Z		True			biological_process											owl:Class	
GO:0006466	biolink:NamedThing	obsolete protein disulfide-isomerase reaction	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	protein disulfide-isomerase reaction|protein disulphide-isomerase reaction			GO:0003756		This term was made obsolete because it presents a molecular function.					True			biological_process											owl:Class	
GO:0007203	biolink:NamedThing	obsolete phosphatidylinositol-4,5-bisphosphate hydrolysis	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	phosphatidylinositol-4,5-bisphosphate hydrolysis					This term was made obsolete because hydrolysis is a reaction, not a process.	GO:0004435				True			biological_process											owl:Class	
GO:0007360	biolink:NamedThing	obsolete positive regulation of posterior gap gene transcription	OBSOLETE. The activation of genes encoding transcription factors in the posterior region of an insect embryo by a combination of maternal regulatory signals and interactions among themselves; exemplified by the activation of expression of the Drosophila knirps gene.	tmpzr1t_l9r_go_relaxed.owl	stimulation of posterior gap gene transcription|up regulation of posterior gap gene transcription|upregulation of posterior gap gene transcription|activation of posterior gap gene|up-regulation of posterior gap gene transcription|activation of posterior gap gene transcription|knirps activation					This term was obsoleted because it represents a GO-CAM model.					True			biological_process											owl:Class	
GO:0045155	biolink:NamedThing	obsolete electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity	OBSOLETE. Enables the directed movement of electrons from the CoQH2-cytochrome c reductase complex and the cytochrome c oxidase complex.	tmpzr1t_l9r_go_relaxed.owl	cytochrome|cytochrome c					This term was obsoleted because it was not clearly defined, it has no corresponding EC or RHEA.					True			molecular_function											owl:Class	
GO:1903157	biolink:NamedThing	obsolete iron ion transmembrane transporter activity involved in iron ion import into cell	OBSOLETE. Any iron ion transmembrane transporter activity that is involved in iron ion import into cell.	tmpzr1t_l9r_go_relaxed.owl	iron transporter activity involved in iron ion import into cell|zinc, iron permease activity involved in iron ion import into cell|multicopper ferroxidase iron transport mediator activity involved in iron ion import into cell|transmembrane iron permease activity involved in iron import into cell|multicopper ferroxidase iron transport mediator activity involved in iron import into cell|zinc, iron permease activity involved in iron import into cell|transmembrane iron permease activity involved in iron ion import into cell|iron transporter activity involved in iron import into cell|transmembrane iron ion permease activity involved in iron ion import into cell|iron ion transmembrane transporter activity involved in iron ion import into cell|iron ion transmembrane transporter activity involved in iron import into cell|transmembrane iron ion permease activity involved in iron import into cell					This term was obsoleted at the TermGenie Gatekeeper stage.		dos	2014-07-09T11:56:16Z		True			molecular_function											owl:Class	
GO:1902186	biolink:NamedThing	obsolete regulation of viral release from host cell	OBSOLETE. Any process that modulates the frequency, rate or extent of viral release from host cell.	tmpzr1t_l9r_go_relaxed.owl	regulation of viral release|regulation of viral exit|regulation of release of virus from host|regulation of viral shedding	https://github.com/geneontology/go-ontology/issues/22168		GO:0019076		This term was obsoleted because there is no evidence that it is a regulated process.		ss	2013-06-04T03:54:03Z		True			biological_process											owl:Class	
GO:0030106	biolink:NamedThing	obsolete MHC class I receptor activity	OBSOLETE. A major histocompatibility complex class I receptor. These display processed antigens from the endocytosed bacteria. MHC class I proteins can form complexes with processed antigen peptides only if the antigen is synthesized in the same cell. As a consequence, T lymphocytes can only bind to class-I-positive cells that are synthesizing the antigen (e.g. virus-infected cells).	tmpzr1t_l9r_go_relaxed.owl	MHC class I receptor activity|class I major histocompatibility complex antigen|major histocompatibility complex class I receptor					This term was made obsolete because the definition is ambiguous and contains incorrect information. To update annotations of gene products that act as receptors for MHC class I protein complexes, use the molecular function term 'MHC class I receptor activity ; GO:0032393'; to update annotations of gene products which are components of MHC class I protein complexes, use the cellular component term 'MHC class I protein complex ; GO:0042612'.	GO:0042612|GO:0032393				True			molecular_function											owl:Class	
GO:0004204	biolink:NamedThing	obsolete caspase-5 activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	caspase-5 activity			GO:0004197		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0051182	biolink:NamedThing	obsolete coenzyme transport	OBSOLETE. The directed movement of a coenzyme into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A coenzyme is any of various nonprotein organic cofactors that are required, in addition to an enzyme and a substrate, for an enzymatic reaction to proceed.	tmpzr1t_l9r_go_relaxed.owl						1. Making inferences in GO about compounds based on the coenzyme role curated by ChEBI creates relationships that are not always true which violates ontological principles for GO; therefore we will cease making these inferences. 2. It is not meaningful to group transport processes that are not all chemically related by the fact that they may be used as a coenzyme.					True			biological_process											owl:Class	
GO:0005646	biolink:NamedThing	obsolete importin	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	karyopherin|importin					This term was made obsolete because it represents a single gene product and not a complex.	GO:0017056|GO:0005634|GO:0005643|GO:0005737				True			cellular_component											owl:Class	
GO:1904162	biolink:NamedThing	obsolete 5'-3' exodeoxyribonuclease activity involved in UV-damage excision repair	OBSOLETE. Any 5'-3' exodeoxyribonuclease activity that is involved in UV-damage excision repair.	tmpzr1t_l9r_go_relaxed.owl	5'-3' exodeoxyribonuclease activity involved in UVDE-dependent excision repair|5'-3' exodeoxyribonuclease activity involved in UVER|5'-3' exodeoxyribonuclease activity involved in UV-damaged DNA endonuclease-dependent excision repair|5'-3' exodeoxyribonuclease activity involved in alternative excision repair|5'-3' exodeoxyribonuclease activity involved in AER					The reason for obsoletion is that this term represents a biological process within a molecular function.	GO:0070914	mah	2015-04-21T14:53:19Z		True			molecular_function											owl:Class	
GO:0039581	biolink:NamedThing	obsolete suppression by virus of host PKR activity via double-stranded RNA binding	OBSOLETE. Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host PKR (protein kinase regulated by RNA) activity by binding to double-stranded RNA (dsRNA). Binding of viral proteins to RNA may sequester or alter the RNA so it can not be recognized by host PKR, or may compete with PKR for dsRNA binding.	tmpzr1t_l9r_go_relaxed.owl	suppression by virus of host PKR activity by binding to dsRNA					The reason for obsoleting this term is that it is too specific. The exact molecular roles of the individual proteins should be captured separately.		bf			True			biological_process											owl:Class	
GO:0106193	biolink:NamedThing	obsolete translocase activity acting on inorganic cations and their chelates linked to the hydrolysis of a diphosphate	OBSOLETE. Catalysis of the translocation of inorganic cations and their chelates linked to the hydrolysis of a diphosphate.	tmpzr1t_l9r_go_relaxed.owl					EC:7.2.3.-	This term was made obsolete because the concept of using the non-4 digit EC classes as parent terms for the transporter banch of the onotolgy was consided confusing.		hjd	2019-05-08T16:55:24Z		True			molecular_function											owl:Class	
GO:0001509	biolink:NamedThing	obsolete legumain activity	OBSOLETE. Catalysis of the hydrolysis of proteins and small-molecule substrates at Asn-Xaa bonds.	tmpzr1t_l9r_go_relaxed.owl	citvac|bean endopeptidase activity|proteinase B|hemoglobinase activity|phaseolin activity|PRSC1 gene product (Homo sapiens)|vicilin peptidohydrolase activity|legumain activity|asparaginyl endopeptidase activity			GO:0004197		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0004240	biolink:NamedThing	obsolete mitochondrial processing peptidase activity	OBSOLETE. Catalysis of the release of N-terminal transit peptides from precursor proteins imported into the mitochondrion, typically with Arg in position P2.	tmpzr1t_l9r_go_relaxed.owl	beta-mitochondrial processing peptidase|matrix processing proteinase|processing enhancing peptidase activity|processing enhancing peptidase (for one of two subunits)|matrix processing peptidase|mitochondrial protein precursor-processing proteinase activity|mitochondrial processing peptidase activity|matrix peptidase|alpha-mitochondrial processing peptidase|MPP			GO:0004222		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0075181	biolink:NamedThing	obsolete positive regulation of symbiont transcription in response to host	OBSOLETE. Any process in which an organism activates, maintains or increases the frequency, rate or extent of its transcription as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/22014				This term was obsoleted because it represents a GO-CAM model.	GO:0006355				True			biological_process											owl:Class	
GO:0038053	biolink:NamedThing	obsolete transcription factor activity, estrogen-activated RNA polymerase II transcription factor binding	OBSOLETE. Combining with estrogen and transmitting the signal to the transcriptional machinery by binding to an RNA polymerase II transcription factor, which may be a single protein or a complex, in order to modulate transcription. For example, estrogen-bound receptors can bind to transcription factor complexes to regulate transcription of genes whose promoters do not contain estrogen response elements.	tmpzr1t_l9r_go_relaxed.owl	estrogen nuclear receptor activity|estrogen-activated RNA polymerase II transcription factor binding transcription factor activity					This term was obsoleted because it represents a GO-CAM model.		bf	2011-11-29T02:42:22Z		True			molecular_function											owl:Class	
GO:0044140	biolink:NamedThing	obsolete negative regulation of growth of symbiont on or near host surface	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the increase in the symbiont's size or mass on or near the cells or tissues of the host organism.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it was partially redundant with other terms and its usage has been inconsistent.		jl	2009-08-04T04:31:26Z		True			biological_process											owl:Class	
GO:0075063	biolink:NamedThing	obsolete positive regulation of invasive hypha growth	OBSOLETE. Any process that activates, maintains or increases the frequency, rate or extent of symbiont invasive hypha formation within host. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of symbiont invasive hypha formation within host|positive regulation of symbiont invasive hypha formation in host	https://github.com/geneontology/go-ontology/issues/19013				This term was obsoleted because there is no evidence that this process exists.					True			biological_process											owl:Class	
GO:0015007	biolink:NamedThing	obsolete electron carrier, chlorophyll electron transport system	OBSOLETE. A molecular entity that serves as an electron acceptor and electron donor in a chlorophyll electron transport system.	tmpzr1t_l9r_go_relaxed.owl	chlorophyll electron carrier|electron carrier, chlorophyll electron transport system					This term was made obsolete because it contains both process and function information.	GO:0009767|GO:0009055				True			molecular_function											owl:Class	
GO:0009469	biolink:NamedThing	obsolete class II cytochrome c	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	class II cytochrome c					This term was made obsolete because it represents a gene product.	GO:0009055				True			molecular_function											owl:Class	
GO:0004183	biolink:NamedThing	obsolete carboxypeptidase E activity	OBSOLETE. Catalysis of the reaction: peptidyl-L-lysine (or peptidyl-L-arginine) + H2O = peptide + L-lysine (or L-arginine). Function is activated by Co2+ and inhibited by 1,10-phenanthroline and other chelating agents.	tmpzr1t_l9r_go_relaxed.owl	carboxypeptidase H activity|enkephalin convertase activity|carboxypeptidase E activity|enkephalin precursor carboxypeptidase activity|cobalt-stimulated chromaffin granule carboxypeptidase activity|insulin granule-associated carboxypeptidase activity|enkephalin-precursor endopeptidase activity|peptidyl-L-lysine(-L-arginine) hydrolase|membrane-bound carboxypeptidase activity			GO:0004181		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0033126	biolink:NamedThing	obsolete positive regulation of GTP catabolic process	OBSOLETE. Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of GTP, guanosine triphosphate.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of GTP catabolism|positive regulation of GTP breakdown|positive regulation of GTP degradation					The reason for making this term obsolete is that it gets misused in cases where phosphates are simply being removed from a small molecule. We found no cases where these molecules genuinely underwent catabolism.	GO:0043547				True			biological_process											owl:Class	
GO:1902885	biolink:NamedThing	obsolete regulation of proteasome-activating ATPase activity	OBSOLETE. Any process that modulates the frequency, rate or extent of proteasome-activating ATPase activity.	tmpzr1t_l9r_go_relaxed.owl	regulation of proteasome channel opening activity|regulation of proteasome channel gating activity|regulation of proteasomal ATPase activity|regulation of ATPase involved in positive regulation of proteasomal protein catabolic process	https://github.com/geneontology/go-ontology/issues/20879				This term was obsoleted because it represents a molecular function.		di	2014-04-04T17:35:23Z		True			biological_process											owl:Class	
GO:2000326	biolink:NamedThing	obsolete negative regulation of nuclear receptor transcription coactivator activity	OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of ligand-dependent nuclear receptor transcription coactivator activity.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of ligand-dependent nuclear receptor transcription co-activator activity|negative regulation of ligand-dependent nuclear receptor transcription coactivator activity					This term was obsoleted because it represents a molecular function.	GO:0140536	vk	2011-01-18T06:30:03Z		True			biological_process											owl:Class	
RO:0002087	biolink:NamedThing	immediately_preceded_by		tmpzr1t_l9r_go_relaxed.owl					RO:0002087									external									immediately_preceded_by			
GO:0022854	biolink:NamedThing	obsolete active large uncharged polar molecule transmembrane transporter activity	OBSOLETE. Catalysis of the transfer of a large uncharged polar molecule from one side of the membrane to the other, up the solute's concentration gradient, by binding the solute and undergoing a series of conformational changes. Transport works equally well in either direction.	tmpzr1t_l9r_go_relaxed.owl	active large uncharged polar molecule transmembrane transporter activity			GO:0022804		This term was made obsolete because 'large uncharged polar molecule' is not a useful chemical grouping term.					True			molecular_function											owl:Class	
GO:0075086	biolink:NamedThing	obsolete negative regulation by host of symbiont transmembrane receptor-mediated cAMP signal transduction	OBSOLETE. Any process in which the host organism stops, prevents, or reduces the frequency, rate or extent of transmembrane receptor-mediated cAMP signal transduction in the symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	negative regulation by host of symbiont transmembrane receptor-mediated cAMP signaling|inhibition by host of symbiont transmembrane receptor-mediated cAMP signal transduction|downregulation by host of symbiont transmembrane receptor-mediated cAMP signal transduction					The reason for obsoletion is that there is no evidence that the host can modulate or regulate a symbiont's signal transduction pathway.					True			biological_process											owl:Class	
GO:1990094	biolink:NamedThing	obsolete positive regulation of N-methyl-D-aspartate receptor clustering	OBSOLETE. The positive regulation of the receptor clustering process in which N-methyl-D-aspartate (NMDA) receptors are localized to distinct domains in the cell membrane.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of NMDA receptor clustering|positive regulation of N-methyl-D-aspartate receptor clustering					This term was obsoleted at the TermGenie Gatekeeper stage.		sl	2013-05-06T17:44:00Z		True			biological_process											owl:Class	
GO:0034725	biolink:NamedThing	obsolete DNA replication-dependent nucleosome disassembly	OBSOLETE. The controlled breakdown of nucleosomes on newly replicated DNA, coupled to strand elongation.	tmpzr1t_l9r_go_relaxed.owl	DNA replication-dependent chromatin disassembly	https://github.com/geneontology/go-ontology/issues/22133				This term was obsoleted because it did not describe a different process from that described by its parent.	GO:0006337				True			biological_process											owl:Class	
GO:0052516	biolink:NamedThing	obsolete positive regulation by organism of symbiont jasmonic acid-mediated defense response	OBSOLETE. Any process by which an organism activates, maintains or increases the frequency, rate or extent of the jasmonic acid-mediated defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	positive regulation by organism of symbiont jasmonic acid-mediated defense response|induction by organism of symbiont jasmonic acid-mediated defense response|positive regulation by organism of symbiont JA-mediated defense response|induction by organism of symbiont JA-mediated defense response					This term was made obsolete because it does not represent a real biological process.					True			biological_process											owl:Class	
GO:0060807	biolink:NamedThing	obsolete regulation of transcription from RNA polymerase II promoter involved in definitive endodermal cell fate specification	OBSOLETE. Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that ultimately results in a cell being specified to adopt a definitive endodermal cell fate.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it represents a GO-CAM model.	GO:0006357|GO:0001714	dph	2009-08-06T02:14:09Z		True			biological_process											owl:Class	
GO:0052199	biolink:NamedThing	obsolete negative regulation of catalytic activity in other organism involved in symbiotic interaction	OBSOLETE. Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of enzyme activity in a second organism, where the two organisms are in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	inhibition of enzyme activity in other organism|down-regulation of enzyme activity in other organism during symbiotic interaction|negative regulation of enzyme activity in other organism during symbiotic interaction|down regulation of enzyme activity in other organism during symbiotic interaction|inhibition of enzyme activity in other organism during symbiotic interaction|downregulation of enzyme activity in other organism during symbiotic interaction	https://github.com/geneontology/go-ontology/issues/21740				This term was obsoleted because it was an unnecessary grouping term.					True			biological_process											owl:Class	
GO:1903291	biolink:NamedThing	obsolete positive regulation of ATP catabolic process	OBSOLETE. Any process that activates or increases the frequency, rate or extent of ATP catabolic process.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of ATP degradation|up-regulation of ATP catabolic process|positive regulation of ATP catabolism|up-regulation of ATP catabolism|activation of ATP breakdown|activation of ATP catabolic process|up regulation of ATP breakdown|positive regulation of ATP degradation|activation of ATP degradation|up regulation of ATP degradation|up-regulation of ATP hydrolysis|upregulation of ATP degradation|positive regulation of ATP breakdown|up regulation of ATP catabolic process|upregulation of ATP catabolic process|activation of ATP hydrolysis|upregulation of ATP breakdown|positive regulation of ATP hydrolysis|up regulation of ATP hydrolysis|up regulation of ATP catabolism|upregulation of ATP catabolism|activation of ATP catabolism|up-regulation of ATP breakdown|upregulation of ATP hydrolysis					The reason for making this term obsolete is that it gets misused in cases where phosphates are simply being removed from a small molecule. We found no cases where these molecules genuinely underwent catabolism.	GO:0032781	rl	2014-08-11T14:36:55Z		True			biological_process											owl:Class	
GO:1901619	biolink:NamedThing	obsolete tRNA methylation in response to nitrogen starvation	OBSOLETE. The posttranscriptional addition of methyl groups to specific residues in a tRNA molecule as a result of deprivation of nitrogen.	tmpzr1t_l9r_go_relaxed.owl								al	2012-11-13T14:36:00Z		True			biological_process											owl:Class	
GO:0052149	biolink:NamedThing	obsolete modulation by symbiont of host peptidase activity	OBSOLETE. The process in which an organism effects a change in host peptidase activity, the catalysis of the hydrolysis of peptide bonds in a protein. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	modulation by symbiont of host protease activity	https://github.com/geneontology/go-ontology/issues/21740				This term was obsoleted because it represents a molecular function.					True			biological_process											owl:Class	
GO:0000757	biolink:NamedThing	obsolete signal transduction involved in regulation of conjugation with mutual genetic exchange	OBSOLETE. A signal transduction process resulting in the relay, amplification or dampening of a signal generated in response to pheromone exposure in organisms that undergo conjugation without cellular fusion.	tmpzr1t_l9r_go_relaxed.owl	signal transduction involved in conjugation without cellular fusion	https://github.com/geneontology/go-ontology/issues/15815				This term was obsoleted because its label and definitions were not clear. It had never been used for annotation.					True			biological_process											owl:Class	
GO:0052312	biolink:NamedThing	obsolete modulation of transcription in other organism involved in symbiotic interaction	OBSOLETE. Any process in which an organism modulates the frequency, rate or extent of transcription in a second organism, where the two organisms are in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	modulation of transcription in other organism during symbiotic interaction					This term was obsoleted because it represents an unnecessary grouping class.					True			biological_process											owl:Class	
GO:0015363	biolink:NamedThing	obsolete dicarboxylate (succinate/fumarate/malate) antiporter activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	dicarboxylate (succinate/fumarate/malate) antiporter activity					This term was made obsolete because it represents a multifunctional gene product.	GO:0015140|GO:0015138|GO:0015141|GO:0005310|GO:0015297				True			molecular_function											owl:Class	
GO:0017043	biolink:NamedThing	obsolete adrenocorticotropin	OBSOLETE. A polypeptide hormone which stimulates the adrenal cortex to synthesize and secrete glucocorticoid hormones.	tmpzr1t_l9r_go_relaxed.owl	adrenocorticotropin|corticotropin					This term was made obsolete because it represents a gene product.	GO:0046886|GO:0046887|GO:0005102				True			molecular_function											owl:Class	
GO:0061464	biolink:NamedThing	obsolete plasma membrane part of cell-substrate junction	OBSOLETE. The part of the plasma membrane that contributes to the structure of a cell-substrate junction.	tmpzr1t_l9r_go_relaxed.owl						The reasons for obsoletion are that (1) this term does not have any gene products associated with them and (2) it can be represented as a GO-CAM.		dph	2012-10-19T11:04:48Z		True			cellular_component											owl:Class	
GO:1900202	biolink:NamedThing	obsolete negative regulation of spread of virus in host, cell to cell	OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of spread of virus in host, cell to cell.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of cell to cell spread of virus within host|down regulation of viral spread within host, cell to cell|inhibition of cell to cell spread of virus within host|downregulation of spread of virus in host, cell to cell|downregulation of spread of virus within host, cell to cell|negative regulation of spread of virus in host, cell to cell|down-regulation of spread of virus within host, cell to cell|inhibition of viral spread within host, cell to cell|downregulation of viral spread within host, cell to cell|negative regulation of spread of virus within host, cell to cell|downregulation of cell to cell spread of virus within host|inhibition of spread of virus within host, cell to cell|negative regulation of viral spread within host, cell to cell|down-regulation of spread of virus in host, cell to cell|down regulation of cell to cell spread of virus within host|down regulation of spread of virus in host, cell to cell|down regulation of spread of virus within host, cell to cell|inhibition of spread of virus in host, cell to cell|down-regulation of cell to cell spread of virus within host|down-regulation of viral spread within host, cell to cell					This term was obsoleted at the TermGenie Gatekeeper stage.		pm	2012-03-21T01:15:51Z		True			biological_process											owl:Class	
GO:0004241	biolink:NamedThing	obsolete alpha-mitochondrial processing peptidase	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	alpha-mitochondrial processing peptidase|alpha-MPP					This term was made obsolete because it represents a gene product.	GO:0005739|GO:0004222				True			molecular_function											owl:Class	
GO:0045559	biolink:NamedThing	obsolete TRAIL receptor 2 biosynthetic process	OBSOLETE. The chemical reactions and pathways resulting in the formation of TRAIL-R2 (TNF-related apoptosis inducing ligand receptor 2), which engages a caspase-dependent apoptotic pathway and mediates apoptosis via the intracellular adaptor molecule FADD/MORT1.	tmpzr1t_l9r_go_relaxed.owl	TRAIL receptor 2 formation|TRAIL receptor 2 anabolism|TRAIL receptor 2 biosynthesis|TRAIL receptor 2 synthesis|tumor necrosis factor receptor superfamily member 10B biosynthetic process	https://github.com/geneontology/go-ontology/issues/19900				The reason for obsoletion is that those represent specific gene products, and genes annotated to those terms should be annotated to 'regulation of gene expression' or 'regulation of transcription' or some signaling term.					True			biological_process											owl:Class	
GO:2001221	biolink:NamedThing	obsolete positive regulation of G2 phase of mitotic cell cycle	OBSOLETE. Any process that activates or increases the frequency, rate or extent of G2 phase of mitotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of G2 phase of mitotic cell cycle					This term was made obsolete because it does not refer to a real biological process.		yaf	2011-11-17T03:28:48Z		True			biological_process											owl:Class	
GO:0030806	biolink:NamedThing	obsolete negative regulation of cyclic nucleotide catabolic process	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of chemical reactions and pathways resulting in the breakdown of cyclic nucleotides.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of cyclic nucleotide degradation|downregulation of cyclic nucleotide catabolic process|negative regulation of cyclic nucleotide catabolism|down-regulation of cyclic nucleotide catabolic process|negative regulation of cyclic nucleotide breakdown|inhibition of cyclic nucleotide catabolic process|down regulation of cyclic nucleotide catabolic process					The reason for obsoletion is that this term represents the regulation of a signaling pathway, not regulation of metabolism.					True			biological_process											owl:Class	
GO:0075021	biolink:NamedThing	obsolete cAMP-mediated activation of appressorium formation	OBSOLETE. Any process that modulates the frequency, rate or extent of symbiont cAMP mediated signal transduction during appressorium formation on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	cyclic AMP mediated activation of appressorium formation					This term was obsoleted because it represents a GO-CAM model.					True			biological_process											owl:Class	
GO:1904084	biolink:NamedThing	obsolete negative regulation of epiboly	OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of epiboly.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of epiboly|down regulation of epiboly|negative regulation of epiboly|downregulation of epiboly|inhibition of epiboly					This term was obsoleted at the TermGenie Gatekeeper stage.		dos	2015-03-25T10:53:40Z		True			biological_process											owl:Class	
GO:0004228	biolink:NamedThing	obsolete gelatinase A activity	OBSOLETE. Catalysis of the cleavage of gelatin type I and collagen types IV, V, VII, X. Cleaves the collagen-like sequence Pro-Gln-Gly-Ile-Ala-Gly-Gln at the Gly-Ile bond.	tmpzr1t_l9r_go_relaxed.owl	72-kDa gelatinase activity|3/4 collagenase activity|MMP-2|matrix metalloproteinase 5|72 kDa gelatinase type A|matrix metalloproteinase 2 activity|collagenase type IV|type IV collagen metalloproteinase|type IV collagenase activity|collagenase IV|MMP 2|gelatinase A activity|type IV collagenase/gelatinase activity			GO:0004222		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0030355	biolink:NamedThing	obsolete small nucleolar ribonucleoprotein	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	snoRNP|small nucleolar ribonucleoprotein			GO:0005732		This term was made obsolete because it describes a cellular component rather than a molecular function.					True			molecular_function											owl:Class	
GO:0100064	biolink:NamedThing	obsolete negative regulation of filamentous growth of a population of unicellular organisms in response to starvation by transcription from RNA polymerase II promoter	OBSOLETE. Any transcription from RNA polymerase II promoter process that negatively regulates filamentous growth of a population of unicellular organisms in response to starvation.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it represents a GO-CAM model.		cjm	2015-04-02T04:13:19Z		True			biological_process											owl:Class	
GO:0015543	biolink:NamedThing	obsolete lactose/glucose efflux transporter activity	OBSOLETE. Catalysis of the reaction: glucose or lactose(in) = glucose or lactose(out).	tmpzr1t_l9r_go_relaxed.owl	lactose/glucose efflux transporter activity					This term was made obsolete because it represents two molecular functions.	GO:0015155				True			molecular_function											owl:Class	
GO:0051197	biolink:NamedThing	obsolete positive regulation of coenzyme metabolic process	OBSOLETE. Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a coenzyme.	tmpzr1t_l9r_go_relaxed.owl	activation of coenzyme metabolic process|up-regulation of coenzyme metabolic process|up regulation of coenzyme metabolic process|upregulation of coenzyme metabolic process|positive regulation of coenzyme and prosthetic group metabolism|positive regulation of coenzyme and prosthetic group metabolic process|positive regulation of coenzyme metabolism|stimulation of coenzyme metabolic process					1. Making inferences in GO about compounds based on the coenzyme role curated by ChEBI creates relationships that are not always true which violates ontological principles for GO; therefore we will cease making these inferences. 2. It is not meaningful to group metabolic processes that are not all metabolically related by the fact that they may be used as a coenzyme.					True			biological_process											owl:Class	
GO:0070216	biolink:NamedThing	obsolete MDM4 binding	OBSOLETE. Binding to an isoform of the MDM4 protein, a negative regulator of p53.	tmpzr1t_l9r_go_relaxed.owl	MDM4 binding|MDMX binding			GO:0097371		This term was made obsolete because it represents binding to an individual protein.					True			molecular_function											owl:Class	
GO:1904993	biolink:NamedThing	obsolete positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in positive regulation of G2/M transition of mitotic cell cycle	OBSOLETE. Any positive regulation of cyclin-dependent protein serine/threonine kinase activity that is involved in positive regulation of G2/M transition of mitotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl	up regulation of cyclin-dependent protein kinase activity involved in positive regulation of mitotic entry|up-regulation of cyclin-dependent protein kinase activity involved in positive regulation of G2/M transition of mitotic cell cycle|upregulation of cyclin-dependent protein kinase activity involved in positive regulation of G2/M transition of mitotic cell cycle|positive regulation of CDK activity involved in positive regulation of mitotic entry|positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in positive regulation of mitotic entry|activation of cyclin-dependent protein kinase activity involved in positive regulation of mitotic entry|upregulation of cyclin-dependent protein kinase activity involved in positive regulation of mitotic entry|stimulation of cyclin-dependent protein kinase activity involved in positive regulation of G2/M transition of mitotic cell cycle|stimulation of cyclin-dependent protein kinase activity involved in positive regulation of mitotic entry|positive regulation of CDK activity involved in positive regulation of G2/M transition of mitotic cell cycle|up regulation of cyclin-dependent protein kinase activity involved in positive regulation of G2/M transition of mitotic cell cycle|activation of cyclin-dependent protein kinase activity involved in positive regulation of G2/M transition of mitotic cell cycle|up-regulation of cyclin-dependent protein kinase activity involved in positive regulation of mitotic entry					This term was obsoleted at the TermGenie Gatekeeper stage.		al	2016-03-01T00:59:41Z		True			biological_process											owl:Class	
GO:0075048	biolink:NamedThing	obsolete cell wall strengthening in symbiont involved in entry into host	OBSOLETE. A process in which the cell wall of the symbiont is strengthened or thickened during penetration into the body, tissues, or cells of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	symbiont cell wall strengthening during entry into host|cell wall thickening in symbiont during entry into host|cell wall strengthening in symbiont during entry into host					This term was obsoleted because there is no evidence that this process exists.					True			biological_process											owl:Class	
GO:0008163	biolink:NamedThing	obsolete DDT resistance	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	DDT resistance			GO:0046680		This term was made obsolete because 'resistance' implies a phenotype rather than a biological process.					True			biological_process											owl:Class	
GO:0035636	biolink:NamedThing	obsolete multi-organism signaling	OBSOLETE. The transfer of information between living organisms.	tmpzr1t_l9r_go_relaxed.owl	signaling between organisms|signaling with other organism|multi-organism signalling|pheromone signaling					This term was obsoleted because it was a grouping term but had no subclasses.		bf	2011-01-14T10:11:25Z		True			biological_process											owl:Class	
GO:0001134	biolink:NamedThing	obsolete transcription regulator recruiting activity	OBSOLETE. The function of binding to an RNA polymerase (RNAP) transcription regulator and recruiting it to the general transcription machinery complex in order to modulate transcription initiation.	tmpzr1t_l9r_go_relaxed.owl	transcription factor recruiting transcription factor activity|transcription factor activity, transcription factor recruiting|transcription factor recruiting activity	https://github.com/geneontology/go-ontology/issues/18561|https://github.com/geneontology/go-ontology/issues/15577		GO:0003712		The reason for obsoletion is that this function is redundant with other terms, most often 'transcription co-regulator activity; GO:0003712'.		krc	2011-01-20T04:57:59Z		True			molecular_function											owl:Class	
GO:0075065	biolink:NamedThing	obsolete growth or development of symbiont in host cell	OBSOLETE. The increase in size or mass of symbiont, or the progression of the symbiont from an initial condition to a later condition, occurring in its host's cell. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	growth or development of symbiont in host cell					This term was made obsolete because it contained a conjunction (or).					True			biological_process											owl:Class	
GO:0003701	biolink:NamedThing	obsolete RNA polymerase I transcription factor activity	OBSOLETE. Functions to initiate or regulate RNA polymerase I transcription.	tmpzr1t_l9r_go_relaxed.owl	RNA polymerase I transcription factor activity					This term was obsoleted because it is essentially identical to a Process term (specifically the Biological Process term which has been selected as a term to consider for reannotation), i.e. it is defined only in terms of the process it acts in and it does NOT convey any information about the molecular nature of the function or whether the function is based on binding DNA, on interacting with other proteins, or some other mechanism. To transfer all annotations without review, the BP term indicated is considered to be equivalent and thus the only appropriate destination for all annotations. To reannotate to a MF term, you will probably need to revisit the original literature or other primary data because this "MF" term was not defined in terms of mechanism of action and there are multiple possibilities in the revised MF structure. In reannotation, please also consider descendent terms of the suggested MF terms as a more specific term may be more appropriate than the MF terms indicated. Please be aware that you may wish to request a new term if the mechanism of action of this gene product is not yet represented or if you are annotating for an RNAP different than one for which there is a specific suggested term. Also note that if there is no information about how the gene product acts, it may be appropriate to annotate to the root term for molecular_function.	GO:0006360|GO:0001181				True			molecular_function											owl:Class	
GO:0072409	biolink:NamedThing	obsolete detection of stimulus involved in meiotic cell cycle checkpoint	OBSOLETE. The series of events in which information about a biological process or quality is received and converted into a molecular signal, contributing to a meiotic cell cycle checkpoint.	tmpzr1t_l9r_go_relaxed.owl	sensing involved in meiotic cell cycle checkpoint|meiotic cell cycle checkpoint sensor mechanism|meiotic cell cycle checkpoint sensor process	https://github.com/geneontology/go-ontology/issues/20976				This term was obsoleted because it corresponds to a molecular function.		mah	2010-12-08T03:47:50Z		True			biological_process											owl:Class	
GO:2000687	biolink:NamedThing	obsolete negative regulation of rubidium ion transmembrane transporter activity	OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of rubidium ion transmembrane transporter activity.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of rubidium cation transmembrane transporter activity|negative regulation of rubidium transmembrane transporter activity|negative regulation of Rb+ transmembrane transporter activity					This term has been obsoleted because it represents an assay, and not a physiological process.		bf	2011-05-11T09:27:32Z		True			biological_process											owl:Class	
GO:0030465	biolink:NamedThing	obsolete autophagic death (sensu Fungi)	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	autophagic death (sensu Fungi)					This term was made obsolete because a more correct term has been created.	GO:0048102				True			biological_process											owl:Class	
GO:0005695	biolink:NamedThing	obsolete chromatid	OBSOLETE. One of the two daughter strands of a duplicated chromosome that become apparent between early prophase and metaphase in mitosis and between diplotene and second metaphase in meiosis.	tmpzr1t_l9r_go_relaxed.owl	chromatid					This term was made obsolete because it is not a unique subcellular component, i.e. the difference between this term and 'chromosome' is based on temporal and process distinctions.	GO:0005694|GO:0000793|GO:0000794				True			cellular_component											owl:Class	
GO:0052181	biolink:NamedThing	obsolete modulation by host of symbiont defense response	OBSOLETE. Any process in which an organism activates, maintains or increases the frequency, rate or extent of the resistance gene-dependent defense response of the symbiont. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl						The reason for obsoletion is that there is no evidence that the host can modulate or regulate a symbiont's defense response.					True			biological_process											owl:Class	
GO:0075705	biolink:NamedThing	obsolete viral entry into host cell via clathrin-mediated endocytosis followed by genetic injection through the endosome membrane	OBSOLETE. The uptake of a virus into a host cell that begins by invagination of a specific region of the host cell plasma membrane around the bound virus to form a clathrin-coated pit, which then pinches off to form a clathrin-coated endocytic vesicles containing the virus. The vesicle then delivers its viral content to early endosomes, and the process ends when the viral nucleic acid is released into the host cytoplasm by its injection through the endosome membrane.	tmpzr1t_l9r_go_relaxed.owl	viral penetration via endocytosis followed by genetic injection through the endosome membrane|viral entry into host cell via clathrin-mediated endocytosis followed by genetic injection through the endosome membrane					This term was made obsolete because it doesn't represent a genuine process. The term injection is mostly used for prokaryotic viruses where there is no endocytosis.		jl	2009-04-23T02:08:06Z		True			biological_process											owl:Class	
GO:1904164	biolink:NamedThing	obsolete negative regulation of triglyceride homeostasis	OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of triglyceride homeostasis.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of triacylglycerol homeostasis|inhibition of triglyceride homeostasis|downregulation of triglyceride homeostasis|down-regulation of triglyceride homeostasis|inhibition of triacylglycerol homeostasis|negative regulation of triacylglycerol homeostasis|downregulation of triacylglycerol homeostasis|down regulation of triacylglycerol homeostasis|down regulation of triglyceride homeostasis					This term was obsoleted at the TermGenie Gatekeeper stage.		rph	2015-04-22T11:04:49Z		True			biological_process											owl:Class	
GO:0000232	biolink:NamedThing	obsolete nuclear interphase chromosome	OBSOLETE. A chromosome found in the nucleus during interphase.	tmpzr1t_l9r_go_relaxed.owl	nuclear interphase chromosome					This term was made obsolete because it is based on a temporal division of the cell cycle.	GO:0000228				True			cellular_component											owl:Class	
GO:0090048	biolink:NamedThing	obsolete negative regulation of transcription regulator activity	OBSOLETE. Any process that decreases the frequency, rate or extent of transcription regulator activity, any molecular function that plays a role in regulating transcription; may bind a promoter or enhancer DNA sequence or interact with a DNA-binding transcription factor.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of transcription regulator activity					At the time of obsoletion, under "regulation of molecular function", a term exists for "regulation of sequence-specific DNA-binding transcription factor activity" and the positive and negative child terms, but no more detailed terms exist. In reannotating, please consider if the paper would support annotation to a regulation term for a specific RNA polymerase. Also consider if what you need would be regulation of protein binding transcription factor activity or any of its child terms instead. If so, please consider making a SF item regarding creation of such a term.		tb	2009-08-07T10:25:04Z		True			biological_process											owl:Class	
GO:0018307	biolink:NamedThing	obsolete enzyme active site formation	OBSOLETE. The modification of part of an enzyme to form the active site.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/15594				This term was obsoleted because it represents a reaction intermediate, not a biological process, see https://en.wikipedia.org/wiki/Active_site#Mechanisms_involved_in_Catalytic_process.					True			biological_process											owl:Class	
GO:0061398	biolink:NamedThing	obsolete negative regulation of transcription from RNA polymerase II promoter in response to copper ion	OBSOLETE. Any process that decreases the frequency, rate or extent of transcription from an RNA polymerase II promoter in response to an copper ion stimulus.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it represents a GO-CAM model.	GO:0071280|GO:0000122	dph	2012-01-10T09:17:02Z		True			biological_process											owl:Class	
GO:0030969	biolink:NamedThing	obsolete mRNA splicing via endonucleolytic cleavage and ligation involved in unfolded protein response	OBSOLETE. The spliceosome-independent cleavage and ligation of the mRNA encoding a UFP-specific transcription factor to remove a single intron, thereby increasing both the translational efficiency of the processed mRNA and the activity of the protein it encodes.	tmpzr1t_l9r_go_relaxed.owl	IRE1-mediated XBP-1 mRNA splicing|Ire1p-mediated HAC-1 mRNA splicing|unconventional splicing of XBP1 mRNA|XBP1 mRNA splicing under conditions of endoplasmic reticulum (ER) stress|XBP1 mRNA splicing, via endonucleolytic cleavage and ligation|HAC1 mRNA splicing|UFP-specific transcription factor mRNA processing involved in endoplasmic reticulum UPR|spliceosome-independent UFP-specific transcription factor mRNA processing|unfolded protein response, cleavage of primary transcript encoding UFP-specific transcription factor|UFP-specific transcription factor mRNA processing during unfolded protein response|unfolded protein response, ligation of mRNA encoding UFP-specific transcription factor by RNA ligase|UFP-specific transcription factor mRNA processing involved in endoplasmic reticulum unfolded protein response|unconventional mRNA splicing involved in UPR|UFP-specific transcription factor mRNA processing involved in ER UPR|non-spliceosomal mRNA splicing in the unfolded protein response pathway|UFP-specific transcription factor mRNA processing involved in ER unfolded protein response|XBP1 mRNA splicing					The reason for obsoletion is that this process represent a single step (molecular function) of the IRE1-mediated unfolded protein response (GO:0036498).	GO:0036498				True			biological_process											owl:Class	
GO:0050662	biolink:NamedThing	obsolete coenzyme binding	OBSOLETE. Binding to a coenzyme, any of various nonprotein organic cofactors that are required, in addition to an enzyme and a substrate, for an enzymatic reaction to proceed.	tmpzr1t_l9r_go_relaxed.owl						1. Making inferences in GO about compounds based on the coenzyme role curated by ChEBI creates relationships that are not always true which violates ontological principles for GO; therefore we will cease making these inferences. 2. It is not meaningful to group binding interactions that are not all chemically related by the fact that they may be used as a coenzyme.					True			molecular_function											owl:Class	
GO:0005562	biolink:NamedThing	obsolete RNA	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	RNA					Note that this term was deleted from GO and was restored to the ontology in Feb 2003 to ensure that the ID is not reused.					True			cellular_component											owl:Class	
GO:0030068	biolink:NamedThing	obsolete lytic viral life cycle	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	lytic viral life cycle					This term was made obsolete because more specific terms were created.	GO:0019058|GO:0044659				True			biological_process											owl:Class	
GO:0015041	biolink:NamedThing	obsolete electron transfer flavoprotein, group II	OBSOLETE. An electron transfer flavoprotein that functions as a housekeeping protein that is synthesized only under certain specific growth conditions and receives electrons from the oxidation of specific substrates, e.g. trimethylamine, carnitine and in nitrogen fixation.	tmpzr1t_l9r_go_relaxed.owl	electron transfer flavoprotein, group II			GO:0009055		This term was made obsolete because it refers to a class of gene products.					True			molecular_function											owl:Class	
GO:0001312	biolink:NamedThing	obsolete replication of extrachromosomal rDNA circles involved in replicative cell aging	OBSOLETE. Replication of rDNA following its excision from the chromosome of dividing cells as they age. Extrachromosomal rDNA forms a circle that contains at least one autonomously replicating sequence (ARS), which supports replication independent of chromosomal replication.	tmpzr1t_l9r_go_relaxed.owl	replication of extrachromosomal rDNA circles during replicative cell aging|replication of extrachromosomal rDNA circles during replicative cell ageing|replication of extrachromosomal ribosomal DNA circles during replicative cell aging	https://github.com/geneontology/go-ontology/issues/20007				This term was obsoleted because it represents an assay, not a true biological process.					True			biological_process											owl:Class	
GO:0031565	biolink:NamedThing	obsolete cytokinesis checkpoint	OBSOLETE. A mitotic cell cycle checkpoint that detects a defect in cytokinesis and negatively regulates G2/M transition.	tmpzr1t_l9r_go_relaxed.owl	contractile ring checkpoint|septin checkpoint					The reason this term was made obsolete is that the two terms cytokinesis checkpoint (GO:0031565) and cytokinesis after mitosis (GO:0000078) were conflated in meaning.	GO:0044878|GO:0044879				True	GO:0000135		biological_process											owl:Class	
GO:0004179	biolink:NamedThing	obsolete membrane alanyl aminopeptidase activity	OBSOLETE. Catalysis of the release of an N-terminal amino acid, Xaa-Xbb- from a peptide, amide or arylamide. Xaa is preferably Ala, but may be most amino acids including Pro (slow action). When a terminal hydrophobic residue is followed by a prolyl residue, the two may be released as an intact Xaa-Pro dipeptide.	tmpzr1t_l9r_go_relaxed.owl	alanine-specific aminopeptidase activity|aminopeptidase N activity|CD13|membrane alanyl aminopeptidase activity|peptidase E activity|aminopeptidase M activity|membrane aminopeptidase I activity|pseudo leucine aminopeptidase activity|membrane alanine aminopeptidase activity|cysteinylglycine dipeptidase activity|cysteinylglycinase activity|alanyl aminopeptidase activity|amino-oligopeptidase activity|L-alanine aminopeptidase activity|particle-bound aminopeptidase activity|microsomal aminopeptidase activity				MetaCyc:3.4.11.2-RXN|EC:3.4.11.2	This term was made obsolete because it represents a gene product.	GO:0004177|GO:0008235				True			molecular_function											owl:Class	
GO:0018779	biolink:NamedThing	obsolete 2-chloro-4,6-dihydroxy-1,3,5-triazine hydrolase activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	2-chloro-4,6-dihydroxy-1,3,5-triazine hydrolase activity					This term was made obsolete because it was derived from a UM-BBD enzyme entry that has been deleted, and no other information can be found to suggest that it is a naturally occurring activity.					True			molecular_function											owl:Class	
GO:0048740	biolink:NamedThing	obsolete striated muscle fiber development	OBSOLETE. The process whose specific outcome is the amplification and progression of myoblasts (muscle precursor cells) into terminally differentiated multinucleated muscle fibers.	tmpzr1t_l9r_go_relaxed.owl	striated muscle fibre development|myogenesis|striated muscle fiber development					This term was made obsolete because it was an unnecessary grouping term. Striated muscle comprises skeletal and cardiac muscle, but GO has opted not to group the muscle fiber development terms.					True			biological_process											owl:Class	
GO:0004189	biolink:NamedThing	obsolete tubulinyl-Tyr carboxypeptidase activity	OBSOLETE. Catalysis of the cleavage of the Glu-Tyr bond to release the C-terminal tyrosine residue from the native tyrosinated tubulin. Inactive on Z-Glu-Tyr.	tmpzr1t_l9r_go_relaxed.owl	tyrosinotubulin carboxypeptidase activity|tubulinyltyrosine carboxypeptidase activity|tubulinyl-tyrosine carboxypeptidase activity|brain I carboxypeptidase activity|tubulinyl-Tyr carboxypeptidase activity|TTCPase activity|tyrosyltubulin carboxypeptidase activity|soluble carboxypeptidase activity|tubulin carboxypeptidase activity|tubulin-tyrosine carboxypeptidase activity|carboxypeptidase-tubulin activity			GO:0004181		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0043946	biolink:NamedThing	obsolete positive regulation of catalytic activity in other organism involved in symbiotic interaction	OBSOLETE. Any process in which an organism activates, maintains or increases the frequency, rate or extent of enzyme activity in a second organism, where the two organisms are in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	activation of enzyme activity in other organism|up-regulation of enzyme activity in other organism during symbiotic interaction|positive regulation of catalytic activity in other organism during symbiotic interaction|activation of enzyme activity in other organism during symbiotic interaction|upregulation of enzyme activity in other organism during symbiotic interaction|up regulation of enzyme activity in other organism during symbiotic interaction	https://github.com/geneontology/go-ontology/issues/21740				This term was obsoleted because it represents a molecular function.	GO:0140677				True			biological_process											owl:Class	
GO:0032236	biolink:NamedThing	obsolete positive regulation of calcium ion transport via store-operated calcium channel activity	OBSOLETE. Any process that activates or increases the frequency, rate or extent of the directed movement of calcium ions via a store-operated calcium channel.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of calcium ion transport via store-operated calcium channel|positive regulation of calcium transport via store-operated calcium channel|up regulation of calcium ion transport via store-operated calcium channel|positive regulation of store-operated calcium channel activity|positive regulation of calcium ion transport via store-operated calcium channel activity|stimulation of calcium ion transport via store-operated calcium channel|upregulation of calcium ion transport via store-operated calcium channel|activation of calcium ion transport via store-operated calcium channel					This term was made obsolete because it is ill-defined: channel activities are part of ion transport processes, and not the other way round.	GO:0015279				True			biological_process											owl:Class	
GO:0016963	biolink:NamedThing	obsolete alpha-2 macroglobulin receptor-associated protein activity	OBSOLETE. Interaction with the alpha-2 macroglobulin receptor and glycoprotein gp330 forming a complex with the alpha-2 macroglobulin receptor light and heavy chains.	tmpzr1t_l9r_go_relaxed.owl	alpha-2 macroglobulin receptor-associated protein activity					This term was made obsolete because it represents a gene product and not a molecular function.	GO:0005102|GO:0005515				True			molecular_function											owl:Class	
GO:0003776	biolink:NamedThing	obsolete muscle motor activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	muscle motor activity			GO:0000146		This term was made obsolete because it includes anatomy information.	GO:0043292|GO:0006936				True			molecular_function											owl:Class	
GO:0075075	biolink:NamedThing	obsolete modulation by host of symbiont adenylate cyclase activity	OBSOLETE. Any process in which the host organism modulates the frequency, rate or extent of the symbiont adenylate cyclase activity, which catalyze the reaction: ATP = 3',5'-cyclic AMP + diphosphate. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/21740				This term was obsoleted because it represents a molecular function.					True			biological_process											owl:Class	
GO:0000759	biolink:NamedThing	obsolete cell morphogenesis involved in conjugation with mutual genetic exchange	OBSOLETE. The change in form (cell shape and size) that occurs during sexual reproduction in order to facilitate direct contact between the compatible mating types in organisms that undergo conjugation without cellular fusion.	tmpzr1t_l9r_go_relaxed.owl	cellular morphogenesis involved in conjugation without cellular fusion					This term was obsoleted because there is no evidence that this process exists.					True			biological_process											owl:Class	
GO:0004973	biolink:NamedThing	obsolete N-methyl-D-aspartate receptor-associated protein activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	N-methyl-D-aspartate receptor-associated protein activity					This term was made obsolete because it represents a gene product and not a molecular function.	GO:0005102|GO:0005515				True			molecular_function											owl:Class	
GO:0003816	biolink:NamedThing	obsolete complement component C1s activity	OBSOLETE. Catalysis of the cleavage of component C4 to C4a and C4b (Arg-Ala bond), and component C2 to C2a and C2b (Lys-Lys or Arg-Lys bond).	tmpzr1t_l9r_go_relaxed.owl	activated complement C1s|complement subcomponent C1s|complement component C1s activity|C1 esterase activity|complement C1s|C1s esterase activity			GO:0004252		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0052442	biolink:NamedThing	obsolete modulation by organism of defense-related symbiont jasmonic acid-mediated signal transduction pathway	OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of symbiont jasmonic acid-mediated signal transduction pathways during the symbiont defense response. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	modulation by organism of defense-related symbiont jasmonic acid-mediated signal transduction pathway|modulation of defense-related symbiont JA-mediated signal transduction pathway by organism					This term was made obsolete because it does not represent a real biological process.					True			biological_process											owl:Class	
GO:0070022	biolink:NamedThing	obsolete transforming growth factor beta receptor complex	OBSOLETE. A homodimeric receptor complex that consists of two TGF-beta receptor monomers.	tmpzr1t_l9r_go_relaxed.owl	transforming growth factor beta receptor complex|TGF-beta receptor complex	https://github.com/geneontology/go-ontology/issues/12676				This term was made obsolete because it does not represent a physiological complex.					True			cellular_component											owl:Class	
GO:0051390	biolink:NamedThing	obsolete inactivation of MAPKKK activity	OBSOLETE. Any process that terminates the activity of the active enzyme MAP kinase kinase kinase (MAPKKK).	tmpzr1t_l9r_go_relaxed.owl	inactivation of MAP kinase kinase kinase activity|termination of MAPKKK activity|termination of MAP kinase kinase kinase activity	https://github.com/geneontology/go-ontology/issues/21308				This term was obsoleted because it represents a molecular function.	GO:0030291|GO:0043409				True			biological_process											owl:Class	
GO:0008954	biolink:NamedThing	obsolete peptidoglycan synthetase activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	peptidoglycan synthetase activity					This term was made obsolete because it was not defined, is ambiguous, and has been used to annotate gene products with very different activities.	GO:0008955|GO:0071972				True			molecular_function											owl:Class	
GO:0015005	biolink:NamedThing	obsolete azurin	OBSOLETE. Brilliant blue copper-containing protein of low molecular weight found in some bacteria; thought to transfer electrons to cytochrome oxidase. This definition includes pseudoazurin.	tmpzr1t_l9r_go_relaxed.owl	azurin					This term was made obsolete because it does not represent a molecular function.	GO:0009055				True			molecular_function											owl:Class	
GO:0015469	biolink:NamedThing	obsolete channel-forming toxin activity	OBSOLETE. A toxin that exerts its effects by forming a channel in a membrane that allows the unregulated passage of substances into and out of the cell.	tmpzr1t_l9r_go_relaxed.owl	channel-forming toxin activity					This term was made obsolete because it represents a class of gene products.	GO:0035915|GO:0046930|GO:0015267|GO:0090729				True			molecular_function											owl:Class	
RO:0002342	biolink:NamedThing	results in transport across		tmpzr1t_l9r_go_relaxed.owl					RO:0002342									external									results_in_transport_across			
GO:0039561	biolink:NamedThing	obsolete suppression by virus of host IRF9 activity by positive regulation of IRF9 localization to nucleus	OBSOLETE. Any process in which a virus stops, prevents, or reduces the activity of host IRF9 (interferon regulatory factor-9) by promoting the nuclear accumulation of IRF9. For example, the reovirus mu2 protein promotes nuclear accumulation of host IRF9 by an as yet unconfirmed-mechanism.	tmpzr1t_l9r_go_relaxed.owl	suppression by virus of host IRF9 activity by nuclear localization of IRF9|suppression of interferon signaling by nuclear accumulation of IRF9					The reason for obsoleting this term is that it is too specific. The exact molecular roles of the individual proteins should be captured separately.		bf	2012-03-09T04:53:44Z		True			biological_process											owl:Class	
GO:0003806	biolink:NamedThing	obsolete coagulation factor XIIa activity	OBSOLETE. Catalysis of the selective cleavage of Arg-Ile bonds in factor VII to form factor VIIa and factor XI to form factor XIa.	tmpzr1t_l9r_go_relaxed.owl	hageman factor activity|hageman factor fragment HFf|hageman factor (activated)|activated beta blood-coagulation factor XII|blood-coagulation factor XIIf|prekallikrein activator|coagulation factor XIIa activity|blood-coagulation factor XIIabeta|blood coagulation factor XII activity|kallikreinogen activator|prealbumin activator|hageman factor beta-fragment			GO:0004252		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0098649	biolink:NamedThing	obsolete response to peptidyl-dipeptidase A inhibitor	OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptidyl-dipeptidase A inhibitor stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to ACE inhibitor|response to angiotensin-converting enzyme inhibitor	https://github.com/geneontology/go-ontology/issues/19725				This term was obsoleted because it does not represent a physiological process.					True			biological_process											owl:Class	
GO:0030636	biolink:NamedThing	obsolete acetate derivative biosynthetic process	OBSOLETE. The chemical reactions and pathways resulting in the formation of derivatives of acetic acid.	tmpzr1t_l9r_go_relaxed.owl	acetate derivative anabolism|acetate derivative biosynthetic process|acetate derivative biosynthesis|acetate derivative formation|acetate derivative synthesis					This term was made obsolete because it is an unnecessary grouping term and has been replaced by terms to describe metabolism of specific compounds.	GO:1900620				True			biological_process											owl:Class	
GO:0075344	biolink:NamedThing	obsolete modulation by symbiont of host protein levels	OBSOLETE. The alteration by an organism of protein levels in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it is a readout, and annotations should be made to more informative terms.					True			biological_process											owl:Class	
GO:0052365	biolink:NamedThing	obsolete catabolism by host of symbiont xylan	OBSOLETE. The chemical reactions and pathways performed by an organism resulting in the breakdown of xylan within the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/21396				This term was obsoleted because there is no evidence it exists.					True			biological_process											owl:Class	
GO:0106184	biolink:NamedThing	obsolete translocation activity acting on other compounds	OBSOLETE. Catalysis of the translocation of other compounds not included in EC:7.1 through EC:7.5 .	tmpzr1t_l9r_go_relaxed.owl					EC:7.6.-.-	This term was made obsolete because the name and scope ( other compounds not included in EC:7.1 through EC:7.5 ) is not good ontological practice.		hjd	2019-04-05T15:56:19Z		True			molecular_function											owl:Class	
GO:0005490	biolink:NamedThing	obsolete cytochrome P450	OBSOLETE. A cytochrome b that has a sulfur atom ligated to the iron of the prosthetic group (heme-thiolate); enzymes:typically monooxygenases acting on lipophilic substrates.	tmpzr1t_l9r_go_relaxed.owl	cytochrome P450					This term was made obsolete because its definition was changed and because it represents a gene product.					True			molecular_function											owl:Class	
GO:0009587	biolink:NamedThing	obsolete phototrophin mediated phototransduction	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	phototrophin mediated phototransduction			GO:0007602							True			biological_process											owl:Class	
GO:0006158	biolink:NamedThing	obsolete deoxyadenosine deaminase reaction	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	deoxyadenosine deaminase reaction			GO:0046936		This term was made obsolete because it represents a molecular function.					True			biological_process											owl:Class	
GO:0100018	biolink:NamedThing	obsolete regulation of glucose import by transcription from RNA polymerase II promoter	OBSOLETE. Any transcription from RNA polymerase II promoter process that regulates glucose import.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it represents a GO-CAM model.		cjm	2015-04-02T04:13:19Z		True			biological_process											owl:Class	
GO:1990872	biolink:NamedThing	obsolete negative regulation of sterol import by negative regulation of transcription from RNA polymerase II promoter	OBSOLETE. Any process that decreases the frequency, rate or extent of sterol import, by down regulation of transcription from an RNA polymerase II promoter.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of sterol influx by stimulation of transcription from RNA polymerase II promoter|negative regulation of sterol uptake by activation of transcription from RNA polymerase II promoter|negative regulation of sterol import by up-regulation of transcription from RNA polymerase II promoter|negative regulation of sterol influx by negative regulation of transcription from RNA polymerase II promoter|negative regulation of sterol import by negative regulation of transcription from Pol II promoter|negative regulation of sterol uptake by upregulation of transcription from RNA polymerase II promoter|negative regulation of sterol influx by upregulation of transcription from RNA polymerase II promoter|negative regulation of sterol uptake by negative regulation of transcription from RNA polymerase II promoter|negative regulation of sterol uptake by up-regulation of transcription from RNA polymerase II promoter|negative regulation of sterol influx by activation of transcription from RNA polymerase II promoter|negative regulation of sterol uptake by up regulation of transcription from RNA polymerase II promoter|negative regulation of sterol import by up regulation of transcription from RNA polymerase II promoter|negative regulation of sterol influx by up-regulation of transcription from RNA polymerase II promoter|negative regulation of sterol import by stimulation of transcription from RNA polymerase II promoter|negative regulation of sterol influx by up regulation of transcription from RNA polymerase II promoter|negative regulation of sterol import by activation of transcription from RNA polymerase II promoter|negative regulation of sterol import by upregulation of transcription from RNA polymerase II promoter|negative regulation of sterol uptake by stimulation of transcription from RNA polymerase II promoter					This term was obsoleted because it represents a GO-CAM model.		rb	2015-09-28T21:22:23Z		True			biological_process											owl:Class	
GO:0052132	biolink:NamedThing	obsolete positive aerotaxis on or near host	OBSOLETE. The directed movement of a motile cell or organism towards a higher concentration of environmental oxygen on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/18819				This term was obsoleted because it represents both a process and a location.					True			biological_process											owl:Class	
GO:0007337	biolink:NamedThing	obsolete unilateral process	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	unilateral process					This term was made obsolete because it gives no indication of what it refers to.					True			biological_process											owl:Class	
GO:0046200	biolink:NamedThing	obsolete m-cresol biosynthetic process	OBSOLETE. The chemical reactions and pathways resulting in the formation of m-cresol (3-hydroxytoluene), the meta-isoform of cresol.	tmpzr1t_l9r_go_relaxed.owl	m-cresol formation|m-cresol anabolism|m-cresol biosynthesis|m-cresol biosynthetic process|m-cresol synthesis			GO:0018925		This term was made obsolete because m-cresol is not synthesized by living organisms and GO does not cover non-biological processes.					True			biological_process											owl:Class	
GO:0035940	biolink:NamedThing	obsolete negative regulation of peptidase activity in other organism	OBSOLETE. Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of peptidase activity, the catalysis of the hydrolysis of peptide bonds in a protein, in a second organism.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of protease activity in other organism|down-regulation of protease activity in other organism|inhibition of protease activity in other organism|downregulation of peptidase activity in other organism|down regulation of peptidase activity in other organism	https://github.com/geneontology/go-ontology/issues/21740				This term was obsoleted because it represents a molecular function.		bf	2011-07-22T02:59:40Z		True			biological_process											owl:Class	
GO:0106196	biolink:NamedThing	obsolete translocase activity acting on inorganic anions linked to the hydrolysis of a nucleoside triphosphate	OBSOLETE. Catalysis of the translocation of inorganic anions linked to the hydrolysis of a nucleoside triphosphate.	tmpzr1t_l9r_go_relaxed.owl					EC:7.3.2.-	This term was made obsolete because the concept of using the non-4 digit EC classes as parent terms for the transporter banch of the onotolgy was consided confusing.		hjd	2019-05-08T18:15:35Z		True			molecular_function											owl:Class	
GO:0009632	biolink:NamedThing	obsolete freezing tolerance	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	freezing tolerance					This term was made obsolete because 'tolerance' implies a phenotype rather than a biological process.	GO:0009409				True			biological_process											owl:Class	
GO:1902335	biolink:NamedThing	obsolete positive chemotaxis involved in neuron migration	OBSOLETE. Any positive chemotaxis that is involved in neuron migration.	tmpzr1t_l9r_go_relaxed.owl	positive chemotaxis involved in neuronal migration|chemoattraction involved in neuron chemotaxis|chemoattraction involved in neuron guidance|positive chemotaxis involved in neuron migration|positive chemotaxis involved in neuron chemotaxis|positive chemotaxis involved in neuron guidance|chemoattraction involved in neuron migration|chemoattraction involved in neuronal migration					This term was obsoleted at the TermGenie Gatekeeper stage.		rl	2013-07-29T12:52:01Z		True			biological_process											owl:Class	
GO:0016227	biolink:NamedThing	obsolete tRNA sulfurtransferase activity	OBSOLETE. Catalysis of the reaction: L-cysteine + 'activated' tRNA = L-serine + tRNA containing a thionucleotide.	tmpzr1t_l9r_go_relaxed.owl	tRNA sulfurtransferase activity|L-cysteine:tRNA sulfurtransferase activity|tRNA sulphurtransferase activity|transfer RNA thiolase activity|transfer ribonucleate sulfurtransferase activity|ribonucleate sulfurtransferase activity|transfer RNA sulfurtransferase activity|RNA sulfurtransferase activity			GO:0034227		This term was made obsolete because tRNA thionucleotide formation is a multistep process; there is no single reaction in which cysteine reacts with an activated tRNA directly	GO:0016783				True			molecular_function											owl:Class	
GO:0036207	biolink:NamedThing	obsolete positive regulation of histone gene expression	OBSOLETE. Any process that increases the frequency, rate or extent of expression of a histone-encoding gene. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of histone gene expression|upregulation of histone gene expression|activation of histone gene expression|positive regulation of expression of histone-encoding gene					This term was obsoleted because it referes to a specific gene product. The gene product should be captured as an annotation extension using 'has input'.	GO:0045944	bf	2012-04-25T09:27:42Z		True			biological_process											owl:Class	
GO:0052178	biolink:NamedThing	obsolete metabolism by symbiont of host cell wall chitin	OBSOLETE. The chemical reactions and pathways performed by an organism involving chitin in the cell wall of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/21469				This term was obsoleted because it represents a molecular function.					True			biological_process											owl:Class	
GO:0023043	biolink:NamedThing	obsolete signaling via lipid mediator	OBSOLETE. The process in which information is sent from one location to another, within a living organism or between living organisms, via a lipid mediator.	tmpzr1t_l9r_go_relaxed.owl	signaling via lipid mediator|signalling via lipid mediator					This term was made obsolete because the meaning of the term is ambiguous.	GO:0023052|GO:0014065		2010-02-16T09:30:50Z		True			biological_process											owl:Class	
GO:0032362	biolink:NamedThing	obsolete FAD catabolic process	OBSOLETE. The chemical reactions and pathways resulting in the breakdown of FAD, the oxidized form of flavin-adenine dinucleotide.	tmpzr1t_l9r_go_relaxed.owl	FAD degradation|FAD catabolism|FAD breakdown|oxidized flavin adenine dinucleotide catabolic process					The reason for making this term obsolete is that it gets misused in cases where phosphates are simply being removed from a small molecule. We found no cases where these molecules genuinely underwent catabolism.					True			biological_process											owl:Class	
GO:0052125	biolink:NamedThing	obsolete energy taxis on or near host	OBSOLETE. The directed movement of a motile cell or organism on or near its host organism in response to physical parameters involved in energy generation, such as light, oxygen, and oxidizable substrates. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it represents both a process and a location.					True			biological_process											owl:Class	
GO:0007150	biolink:NamedThing	obsolete growth pattern	OBSOLETE. A process whereby cells develop a specific morphology under a specific set of circumstances.	tmpzr1t_l9r_go_relaxed.owl	growth pattern					This term was made obsolete because the original meaning of the term is unclear, the current definition is incorrect, and it does not describe a biological process.	GO:0040007				True			biological_process											owl:Class	
GO:0009004	biolink:NamedThing	obsolete signal peptidase I activity	OBSOLETE. Catalysis of the cleavage of N-terminal leader sequences from secreted and periplasmic proteins precursor.	tmpzr1t_l9r_go_relaxed.owl	propeptidase activity|signal proteinase activity|Escherichia coli leader peptidase|SPase I activity|prokaryotic leader peptidase|pilin leader peptidase|prokaryotic signal proteinase|eukaryotic signal peptidase|eukaryotic signal proteinase|signal peptidase I activity|leader peptide hydrolase activity|signal peptide hydrolase activity|HOSP|SPC|prokaryotic signal peptidase|leader peptidase I|bacterial leader peptidase 1|phage-procoat-leader peptidase activity|bacterial leader peptidase I activity|signalase activity|leader proteinase activity|leader peptidase activity|PuIO prepilin peptidase			GO:0004252		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:1903994	biolink:NamedThing	obsolete positive regulation of protein stabilization	OBSOLETE. Any process that activates or increases the frequency, rate or extent of protein stabilization.	tmpzr1t_l9r_go_relaxed.owl	upregulation of protein sequestering|upregulation of positive regulation of protein stability|up-regulation of positive regulation of protein stability|positive regulation of protein stabilization activity|up-regulation of protein sequestering|up regulation of positive regulation of protein stability|up-regulation of protein stabilization activity|up regulation of protein sequestering|upregulation of protein stabilization|positive regulation of protein sequestering|positive regulation of lysosomal protein stabilization|up-regulation of protein stabilization|activation of lysosomal protein stabilization|positive regulation of protein stabilization|activation of protein stabilization activity|activation of positive regulation of protein stability|up regulation of protein stabilization|positive regulation of positive regulation of protein stability|upregulation of lysosomal protein stabilization|activation of protein stabilization|up regulation of lysosomal protein stabilization|activation of protein sequestering|up-regulation of lysosomal protein stabilization|up regulation of protein stabilization activity|upregulation of protein stabilization activity					This term was made obsolete because it was created in error.	GO:0050821	pga	2015-03-05T13:33:00Z		True			biological_process											owl:Class	
GO:0007244	biolink:NamedThing	obsolete MAPKKK cascade (mating sensu Saccharomyces)	OBSOLETE. MAPKKK cascade involved in transduction of mating pheromone signal, as described in Saccharomyces.	tmpzr1t_l9r_go_relaxed.owl	MAPKKK cascade (mating sensu Saccharomyces)			GO:0000750		This term was made obsolete because it is a gene product specific term.					True			biological_process											owl:Class	
GO:1902352	biolink:NamedThing	obsolete negative regulation of filamentous growth of a population of unicellular organisms in response to starvation by negative regulation of transcription from RNA polymerase II promoter	OBSOLETE. A negative regulation of transcription from RNA polymerase II promoter that results in negative regulation of filamentous growth of a population of unicellular organisms in response to starvation.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it represents a GO-CAM model.		bf	2013-08-14T09:35:43Z		True			biological_process											owl:Class	
GO:0008572	biolink:NamedThing	obsolete nucleoplasmin ATPase activity	OBSOLETE. Catalysis of the reaction: ATP + H2O = ADP + phosphate. The hydrolysis of ATP required for the ATP-dependent assembly of nucleosome cores, in decondensation of sperm chromatin and in other histone-involving processes.	tmpzr1t_l9r_go_relaxed.owl	nucleoplasmin ATPase activity			GO:0016887		This term was made obsolete because it represents a class of gene products, and its definition incorporates process information.	GO:0006333				True			molecular_function											owl:Class	
GO:2001273	biolink:NamedThing	obsolete regulation of glucose import in response to insulin stimulus	OBSOLETE. Any process that modulates the frequency, rate or extent of glucose import in response to insulin stimulus.	tmpzr1t_l9r_go_relaxed.owl	regulation of cellular glucose import in response to insulin stimulus	https://github.com/geneontology/go-ontology/issues/15961				This term was obsoleted because it represents a GO-CAM model.		vk	2011-12-13T12:29:31Z		True			biological_process											owl:Class	
GO:0017141	biolink:NamedThing	obsolete antibiotic susceptibility/resistance	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	antibiotic susceptibility/resistance			GO:0046677		This term was made obsolete because 'susceptibility/resistance' implies a phenotype rather than a biological process.					True			biological_process											owl:Class	
GO:0052471	biolink:NamedThing	obsolete modulation by organism of systemic acquired resistance in symbiont	OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of systemic acquired resistance in the symbiont organism; systemic acquired resistance is a salicylic acid-mediated response that confers broad spectrum systemic resistance. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	modulation by organism of systemic acquired resistance in symbiont					This term was made obsolete because it does not represent a real biological process.					True			biological_process											owl:Class	
GO:0075117	biolink:NamedThing	obsolete suppression by symbiont of host transmembrane receptor-mediated cAMP signal transduction	OBSOLETE. Any process in which the symbiont stops, prevents, or reduces the frequency, rate or extent of host transmembrane receptor-mediated cAMP signal transduction. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	inhibition by symbiont of host transmembrane receptor-mediated cAMP signal transduction|downregulation by symbiont of host transmembrane receptor-mediated cAMP signal transduction|negative regulation by symbiont of host transmembrane receptor-mediated cAMP signaling					The reason for obsoletion is that there is no evidence that this process exists.					True			biological_process											owl:Class	
GO:0051827	biolink:NamedThing	obsolete growth or development on or near surface of other organism during symbiotic interaction	OBSOLETE. The increase in size or mass of an organism, or the progression of an organism from an initial condition to a later condition, occurring on or near the exterior of a second organism, where the two organisms are in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	growth or development on or near surface of other organism during symbiotic interaction					This term was made obsolete because it contained a conjunction (or).	GO:0044111				True			biological_process											owl:Class	
GO:0010679	biolink:NamedThing	obsolete cinnamic acid biosynthetic process involved in salicylic acid metabolism	OBSOLETE. The chemical reactions and pathways resulting in the formation of cinnamic acid, 3-phenyl-2-propenoic acid, which is then utilized in the metabolism of salicylic acid.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/18200				This term was obsoleted because it does not represent a specific pathway.					True			biological_process											owl:Class	
GO:0030819	biolink:NamedThing	obsolete positive regulation of cAMP biosynthetic process	OBSOLETE. Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate).	tmpzr1t_l9r_go_relaxed.owl	positive regulation of adenosine 3',5'-cyclophosphate biosynthesis|positive regulation of 3',5'-cAMP biosynthesis|activation of cAMP biosynthetic process|positive regulation of 3',5' cAMP biosynthesis|positive regulation of cAMP anabolism|positive regulation of 3',5' cAMP biosynthetic process|positive regulation of cAMP biosynthesis|positive regulation of adenosine 3',5'-cyclophosphate biosynthetic process|up-regulation of cAMP biosynthetic process|positive regulation of cAMP synthesis|positive regulation of 3',5'-cAMP biosynthetic process|stimulation of cAMP biosynthetic process|positive regulation of cyclic AMP biosynthetic process|positive regulation of cyclic AMP biosynthesis|positive regulation of cAMP formation|upregulation of cAMP biosynthetic process|up regulation of cAMP biosynthetic process	https://github.com/geneontology/go-ontology/issues/14718									True			biological_process											owl:Class	
GO:0017093	biolink:NamedThing	obsolete sterol regulatory element-binding protein protease activity	OBSOLETE. Catalysis of the hydrolysis of peptide bonds within a sterol regulatory element binding protein (SREBP). SREBPs are transcription factors that bind sterol regulatory elements (SREs), DNA motifs found in the promoters of target genes.	tmpzr1t_l9r_go_relaxed.owl	SREBP protease activity|sterol regulatory element-binding protein protease activity			GO:0008233		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0016583	biolink:NamedThing	obsolete nucleosome modeling	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	nucleosome modeling					This term was made obsolete because it has been replaced by more specific terms.	GO:0006334				True			biological_process											owl:Class	
GO:0075180	biolink:NamedThing	obsolete regulation of transcription in response to host	OBSOLETE. Any process in which the symbiont organism modulates the frequency, rate or extent of its transcription as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/22014				This term was obsoleted because it represents a GO-CAM model.	GO:0006355				True			biological_process											owl:Class	
GO:0004237	biolink:NamedThing	obsolete membrane dipeptidase activity	OBSOLETE. Catalysis of the hydrolysis of dipeptides.	tmpzr1t_l9r_go_relaxed.owl	dehydropeptidase I activity|nonspecific dipeptidase activity|dipeptidyl hydrolase activity|membrane dipeptidase activity|DPH I activity|dipeptide hydrolase|aminodipeptidase activity|MDP|glycosyl-phosphatidylinositol-anchored renal dipeptidase activity|renal dipeptidase activity|microsomal dipeptidase activity|dehydropeptidase I (DPH I)				EC:3.4.13.19|MetaCyc:3.4.13.19-RXN	This term was made obsolete because it represents a gene product.	GO:0016805|GO:0008235				True			molecular_function											owl:Class	
GO:0001564	biolink:NamedThing	obsolete resistance to pathogenic protozoa	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	resistance to pathogenic protozoa			GO:0001562		This term was made obsolete because 'resistance' implies a phenotype rather than a biological process.					True			biological_process											owl:Class	
GO:0009474	biolink:NamedThing	obsolete nonaheme cytochrome c	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	nonaheme cytochrome c					This term was made obsolete because it represents a gene product.	GO:0009055				True			molecular_function											owl:Class	
GO:1990940	biolink:NamedThing	obsolete microtubule sliding involved in mitotic spindle elongation	OBSOLETE. The movement of one microtubule along another microtubule involved in mitotic spindle elongation.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted at the TermGenie Gatekeeper stage.		vw	2016-04-04T11:06:41Z		True			biological_process											owl:Class	
GO:0005192	biolink:NamedThing	obsolete urinary protein	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	urinary protein					This term was made obsolete because it describes presence in body fluids rather than an activity.					True			molecular_function											owl:Class	
GO:0051854	biolink:NamedThing	obsolete induction in symbiont of tumor, nodule, or growth containing transformed cells	OBSOLETE. The process by which an organism causes the formation in its symbiont organism of an abnormal growth whose cells have been transformed and continue to exist in the absence of the first organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	induction in symbiont of tumor, nodule, or growth containing transformed cells					This term was made obsolete because it does not represent a real process that exists in nature.					True			biological_process											owl:Class	
GO:0052135	biolink:NamedThing	obsolete negative aerotaxis in host	OBSOLETE. The directed movement of a motile cell or organism towards a lower concentration of environmental oxygen within its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	negative aerotaxis within host	https://github.com/geneontology/go-ontology/issues/18819				This term was obsoleted because it represents both a process and a location.					True			biological_process											owl:Class	
GO:0052383	biolink:NamedThing	obsolete induction by organism of symbiont innate immunity	OBSOLETE. The activation by an organism of the innate immune response of the symbiont organism; the innate immune response is the symbiont's first line of defense against infection. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	induction by organism of symbiont innate immunity|activation by organism of symbiont innate immunity|induction by organism of symbiont innate immune response|activation by organism of symbiont innate immune response					This term was made obsolete because it does not represent a real biological process.					True			biological_process											owl:Class	
GO:0005563	biolink:NamedThing	obsolete transfer RNA	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	transfer RNA			GO:0030533		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:1903484	biolink:NamedThing	obsolete negative regulation of maintenance of mitotic actomyosin contractile ring localization	OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of maintenance of mitotic actomyosin contractile ring localization.	tmpzr1t_l9r_go_relaxed.owl	inhibition of maintenance of mitotic actomyosin contractile ring localization|down regulation of maintenance of contractile ring localization involved in cell cycle cytokinesis involved in mitotic cell cycle|down-regulation of maintenance of mitotic actomyosin contractile ring localization|down regulation of maintenance of contractile ring localization involved in cytokinesis during cell cycle involved in mitotic cell cycle|negative regulation of maintenance of contractile ring localization involved in cell cycle cytokinesis involved in mitotic cell cycle|down regulation of maintenance of contractile ring localisation involved in cell cycle cytokinesis involved in mitotic cell cycle|downregulation of maintenance of contractile ring localization involved in cytokinesis during cell cycle involved in mitotic cell cycle|downregulation of cytokinetic ring anchoring involved in mitotic cell cycle|downregulation of maintenance of mitotic actomyosin contractile ring localization|negative regulation of maintenance of contractile ring localization involved in cytokinesis during cell cycle involved in mitotic cell cycle|downregulation of maintenance of contractile ring localisation involved in cell cycle cytokinesis involved in mitotic cell cycle|down-regulation of maintenance of contractile ring localization involved in cytokinesis during cell cycle involved in mitotic cell cycle|negative regulation of maintenance of contractile ring localisation involved in cell cycle cytokinesis involved in mitotic cell cycle|inhibition of maintenance of contractile ring localisation involved in cell cycle cytokinesis involved in mitotic cell cycle|down regulation of maintenance of mitotic actomyosin contractile ring localization|down regulation of cytokinetic ring anchoring involved in mitotic cell cycle|down-regulation of maintenance of contractile ring localization involved in cell cycle cytokinesis involved in mitotic cell cycle|inhibition of cytokinetic ring anchoring involved in mitotic cell cycle|down-regulation of maintenance of contractile ring localisation involved in cell cycle cytokinesis involved in mitotic cell cycle|down-regulation of cytokinetic ring anchoring involved in mitotic cell cycle|downregulation of maintenance of contractile ring localization involved in cell cycle cytokinesis involved in mitotic cell cycle|inhibition of maintenance of contractile ring localization involved in cell cycle cytokinesis involved in mitotic cell cycle|negative regulation of cytokinetic ring anchoring involved in mitotic cell cycle|inhibition of maintenance of contractile ring localization involved in cytokinesis during cell cycle involved in mitotic cell cycle					The reason for obsoletion is that this term represents a GO-CAM model.		vw	2014-09-23T16:12:28Z		True			biological_process											owl:Class	
exports	biolink:NamedThing	exports		tmpzr1t_l9r_go_relaxed.owl					RO:0002345									external									exports			
GO:0003079	biolink:NamedThing	obsolete positive regulation of natriuresis	OBSOLETE. Any process that activates or increases the frequency, rate or extent of natriuresis.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of natriuresis					This term was made obsolete because its definition was inaccurate.	GO:0035815				True			biological_process											owl:Class	
GO:0008581	biolink:NamedThing	obsolete ubiquitin-specific protease 5 activity	OBSOLETE. Catalysis of the hydrolysis of the Gly76-Lys48 isopeptide bond of polyubiquitin.	tmpzr1t_l9r_go_relaxed.owl	ubiquitin isopeptidase T activity|ubiquitin-specific protease 5 activity			GO:0004843		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:2001219	biolink:NamedThing	obsolete positive regulation of S/G2 transition of mitotic cell cycle	OBSOLETE. Any process that activates or increases the frequency, rate or extent of S/G2 transition of mitotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of S/G2 transition of mitotic cell cycle					This term was made obsolete because it does not refer to a real biological process.		dph	2011-11-16T09:14:50Z		True			biological_process											owl:Class	
GO:0003817	biolink:NamedThing	obsolete complement factor D activity	OBSOLETE. Catalysis of the cleavage of component factor B (Arg-Lys) when in complex with C3b or with cobra venom factor (CVF).	tmpzr1t_l9r_go_relaxed.owl	adipsin|properdin factor D esterase activity|complement factor D activity|C3 proactivator convertase activity|C3 convertase activator activity|factor D (complement)|factor D			GO:0004252		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:1901226	biolink:NamedThing	obsolete positive regulation of transcription from RNA polymerase II promoter involved in heart development	OBSOLETE. Any process that activates or increases the frequency, rate or extent of regulation of transcription from RNA polymerase II promoter involved in heart development.	tmpzr1t_l9r_go_relaxed.owl	upregulation of global transcription regulation from Pol II promoter involved in dorsal vessel development|activation of regulation of gene-specific transcription from RNA polymerase II promoter involved in cardiac development|upregulation of regulation of transcription from Pol II promoter involved in dorsal vessel development|up-regulation of regulation of gene-specific transcription from RNA polymerase II promoter involved in heart development|up-regulation of regulation of transcription from Pol II promoter involved in cardiac development|up regulation of regulation of transcription from RNA polymerase II promoter, global involved in cardiac development|activation of regulation of transcription from RNA polymerase II promoter involved in dorsal vessel development|activation of regulation of gene-specific transcription from RNA polymerase II promoter involved in dorsal vessel development|up regulation of regulation of global transcription from Pol II promoter involved in cardiac development|upregulation of regulation of transcription from RNA polymerase II promoter, global involved in heart development|up-regulation of regulation of gene-specific transcription from RNA polymerase II promoter involved in dorsal vessel development|upregulation of regulation of global transcription from Pol II promoter involved in dorsal vessel development|up-regulation of regulation of global transcription from Pol II promoter involved in cardiac development|positive regulation of regulation of gene-specific transcription from RNA polymerase II promoter involved in cardiac development|activation of regulation of transcription from RNA polymerase II promoter, global involved in cardiac development|up-regulation of global transcription regulation from Pol II promoter involved in dorsal vessel development|upregulation of regulation of transcription from RNA polymerase II promoter, global involved in dorsal vessel development|up regulation of regulation of gene-specific transcription from RNA polymerase II promoter involved in heart development|positive regulation of regulation of transcription from RNA polymerase II promoter involved in dorsal vessel development|up regulation of regulation of transcription from RNA polymerase II promoter involved in dorsal vessel development|upregulation of regulation of gene-specific transcription from RNA polymerase II promoter involved in heart development|positive regulation of regulation of transcription from RNA polymerase II promoter involved in cardiac development|positive regulation of transcription from RNA polymerase II promoter involved in heart development|upregulation of regulation of transcription from RNA polymerase II promoter involved in heart development|up-regulation of global transcription regulation from Pol II promoter involved in heart development|upregulation of regulation of global transcription from Pol II promoter involved in heart development|positive regulation of regulation of transcription from Pol II promoter involved in dorsal vessel development|up-regulation of regulation of transcription from RNA polymerase II promoter, global involved in dorsal vessel development|activation of regulation of global transcription from Pol II promoter involved in cardiac development|activation of regulation of transcription from RNA polymerase II promoter involved in cardiac development|activation of regulation of global transcription from Pol II promoter involved in dorsal vessel development|up regulation of global transcription regulation from Pol II promoter involved in cardiac development|up regulation of regulation of global transcription from Pol II promoter involved in heart development|up-regulation of regulation of transcription from Pol II promoter involved in heart development|positive regulation of regulation of transcription from RNA polymerase II promoter, global involved in heart development|up-regulation of global transcription regulation from Pol II promoter involved in cardiac development|activation of global transcription regulation from Pol II promoter involved in dorsal vessel development|upregulation of regulation of global transcription from Pol II promoter involved in cardiac development|up-regulation of regulation of transcription from RNA polymerase II promoter, global involved in cardiac development|activation of regulation of transcription from RNA polymerase II promoter, global involved in dorsal vessel development|upregulation of global transcription regulation from Pol II promoter involved in heart development|up regulation of regulation of gene-specific transcription from RNA polymerase II promoter involved in cardiac development|positive regulation of regulation of transcription from Pol II promoter involved in heart development|positive regulation of regulation of gene-specific transcription from RNA polymerase II promoter involved in dorsal vessel development|positive regulation of regulation of transcription from RNA polymerase II promoter, global involved in dorsal vessel development|up regulation of regulation of transcription from Pol II promoter involved in dorsal vessel development|positive regulation of regulation of global transcription from Pol II promoter involved in heart development|activation of regulation of transcription from Pol II promoter involved in heart development|activation of regulation of gene-specific transcription from RNA polymerase II promoter involved in heart development|upregulation of regulation of transcription from Pol II promoter involved in cardiac development|upregulation of regulation of transcription from RNA polymerase II promoter involved in cardiac development|activation of regulation of transcription from Pol II promoter involved in dorsal vessel development|up regulation of regulation of transcription from RNA polymerase II promoter involved in cardiac development|up regulation of global transcription regulation from Pol II promoter involved in heart development|upregulation of regulation of gene-specific transcription from RNA polymerase II promoter involved in dorsal vessel development|up regulation of regulation of transcription from RNA polymerase II promoter, global involved in heart development|positive regulation of regulation of global transcription from Pol II promoter involved in cardiac development|upregulation of regulation of transcription from RNA polymerase II promoter, global involved in cardiac development|up regulation of regulation of transcription from Pol II promoter involved in heart development|up-regulation of regulation of transcription from RNA polymerase II promoter involved in heart development|up regulation of regulation of gene-specific transcription from RNA polymerase II promoter involved in dorsal vessel development|activation of global transcription regulation from Pol II promoter involved in heart development|activation of regulation of transcription from RNA polymerase II promoter involved in heart development|up-regulation of regulation of gene-specific transcription from RNA polymerase II promoter involved in cardiac development|up-regulation of regulation of transcription from RNA polymerase II promoter involved in cardiac development|activation of global transcription regulation from Pol II promoter involved in cardiac development|upregulation of regulation of transcription from Pol II promoter involved in heart development|positive regulation of global transcription regulation from Pol II promoter involved in heart development|up regulation of regulation of transcription from RNA polymerase II promoter involved in heart development|activation of regulation of global transcription from Pol II promoter involved in heart development|up-regulation of regulation of global transcription from Pol II promoter involved in heart development|up-regulation of regulation of transcription from Pol II promoter involved in dorsal vessel development|positive regulation of global transcription regulation from Pol II promoter involved in cardiac development|positive regulation of regulation of transcription from Pol II promoter involved in cardiac development|up-regulation of regulation of transcription from RNA polymerase II promoter, global involved in heart development|upregulation of regulation of transcription from RNA polymerase II promoter involved in dorsal vessel development|up-regulation of regulation of global transcription from Pol II promoter involved in dorsal vessel development|activation of regulation of transcription from RNA polymerase II promoter, global involved in heart development|up regulation of global transcription regulation from Pol II promoter involved in dorsal vessel development|activation of regulation of transcription from Pol II promoter involved in cardiac development|positive regulation of global transcription regulation from Pol II promoter involved in dorsal vessel development|up regulation of regulation of transcription from Pol II promoter involved in cardiac development|up regulation of regulation of global transcription from Pol II promoter involved in dorsal vessel development|positive regulation of regulation of global transcription from Pol II promoter involved in dorsal vessel development|up-regulation of regulation of transcription from RNA polymerase II promoter involved in dorsal vessel development|positive regulation of regulation of transcription from RNA polymerase II promoter, global involved in cardiac development|up regulation of regulation of transcription from RNA polymerase II promoter, global involved in dorsal vessel development|upregulation of regulation of gene-specific transcription from RNA polymerase II promoter involved in cardiac development|upregulation of global transcription regulation from Pol II promoter involved in cardiac development|positive regulation of regulation of gene-specific transcription from RNA polymerase II promoter involved in heart development					This term was obsoleted at the TermGenie Gatekeeper stage.	GO:0045944|GO:0007507	rl	2012-08-07T07:04:32Z		True			biological_process											owl:Class	
GO:1900456	biolink:NamedThing	obsolete regulation of invasive growth in response to glucose limitation by regulation of transcription from RNA polymerase II promoter	OBSOLETE. Any process that modulates the frequency, rate or extent of invasive growth in response to glucose limitation by modulating the frequency, rate or extent of transcription from an RNA polymerase II promoter.	tmpzr1t_l9r_go_relaxed.owl	regulation of colony morphology by regulation of transcription from RNA polymerase II promoter|regulation of invasive growth in response to glucose limitation by regulation of transcription from RNA polymerase II promoter					This term was obsoleted at the TermGenie Gatekeeper stage.		dgf	2012-05-01T05:42:03Z		True			biological_process											owl:Class	
GO:0046022	biolink:NamedThing	obsolete positive regulation of transcription from RNA polymerase II promoter during mitotic cell cycle	OBSOLETE. Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter that occurs during the mitotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of transcription from RNA polymerase II promoter, mitotic|up-regulation of transcription from RNA polymerase II promoter during mitosis|stimulation of transcription from RNA polymerase II promoter during mitosis|mitotic activation of transcription from Pol II promoter|positive regulation of transcription from Pol II promoter during mitosis|up regulation of transcription from RNA polymerase II promoter during mitosis|activation of transcription from RNA polymerase II promoter during mitosis|upregulation of transcription from RNA polymerase II promoter during mitosis	https://github.com/geneontology/go-ontology/issues/14896				The reason for obsoletion is that 'during' should be captured using an annotation extension.	GO:0044772|GO:0045944				True			biological_process											owl:Class	
GO:0005015	biolink:NamedThing	obsolete neurotrophin TRKB receptor activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	neurotrophin TRKB receptor activity					This term was made obsolete because it represents a gene product.	GO:0043121|GO:0004714|GO:0048403|GO:0007165				True			molecular_function											owl:Class	
GO:2000582	biolink:NamedThing	obsolete positive regulation of microtubule motor activity, plus-end-directed	OBSOLETE. Any process that activates or increases the frequency, rate or extent of ATP-dependent microtubule motor activity, plus-end-directed.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of ATP-dependent microtubule motor activity, plus-end-directed|positive regulation of plus-end-directed kinesin ATPase activity|positive regulation of kinesin activity|positive regulation of kinesin ATP phosphohydrolase (plus-end-directed)|positive regulation of plus-end-directed microtubule motor activity	https://github.com/geneontology/go-ontology/issues/21626				This term was obsoleted because it represents a molecular function.	GO:0140660	bf	2011-04-05T08:39:52Z		True			biological_process											owl:Class	
GO:0006512	biolink:NamedThing	obsolete ubiquitin cycle	OBSOLETE. The cyclical process by which one or more ubiquitin groups are added to (ubiquitination) and removed from (deubiquitination) a protein.	tmpzr1t_l9r_go_relaxed.owl	ubiquitin cycle					This term was made obsolete because it implies that every protein that is ubiquitinated is also subsequently deubiquinitated, which is not true. Also, the process ontology does not include analogous terms for other small modifiers.					True			biological_process											owl:Class	
GO:0003782	biolink:NamedThing	obsolete F-actin capping activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	F-actin capping activity			GO:0051016		This term was made obsolete because it describes a biological process.					True			molecular_function											owl:Class	
GO:0052011	biolink:NamedThing	obsolete catabolism by symbiont of host cell wall pectin	OBSOLETE. The chemical reactions and pathways performed by an organism resulting in the breakdown of pectin in the host cell wall. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	catabolism by organism of host cell wall pectin	https://github.com/geneontology/go-ontology/issues/21469				This term was obsoleted because it represents a molecular function.					True			biological_process											owl:Class	
GO:0018927	biolink:NamedThing	obsolete methionine and threonine metabolic process	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	methionine and threonine metabolic process					This term was made obsolete because its use of 'and' was causing violations to the true-path rule.	GO:0006555|GO:0006566				True			biological_process											owl:Class	
GO:0061306	biolink:NamedThing	obsolete DNA strand renaturation involved in double-strand break repair	OBSOLETE. The identification and annealing of complementary base pairs in single-strand DNA that contributes to double-strand break repair.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/14671				This term was obsoleted because it represents a molecular function.	GO:0036310|GO:0006302	dph	2010-09-21T09:36:47Z		True			biological_process											owl:Class	
GO:0085012	biolink:NamedThing	obsolete interaction with host via protein secreted by Tat complex	OBSOLETE. An interaction with the host organism mediated by a substance secreted by the symbiont organism by a Tat complex. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	interaction with host via protein secreted by Tat secretion system					This term was obsoleted because it conflated the process in which a gene product is involved with the secretion system by which it reaches its target.		jl	2010-02-10T03:29:37Z		True			biological_process											owl:Class	
GO:0009622	biolink:NamedThing	obsolete resistance to pathogenic fungi	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	resistance to pathogenic fungi			GO:0009620		This term was made obsolete because 'resistance' implies a phenotype rather than a biological process.					True			biological_process											owl:Class	
GO:2001218	biolink:NamedThing	obsolete negative regulation of S/G2 transition of mitotic cell cycle	OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of S/G2 transition of mitotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of S/G2 transition of mitotic cell cycle					This term was made obsolete because it does not refer to a real biological process.		dph	2011-11-16T09:14:47Z		True			biological_process											owl:Class	
GO:0034225	biolink:NamedThing	obsolete regulation of transcription from RNA polymerase II promoter in response to zinc ion starvation	OBSOLETE. Modulation of the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is deprived of zinc ions.	tmpzr1t_l9r_go_relaxed.owl	regulation of transcription from RNA polymerase II promoter in response to zinc ion limitation|regulation of transcription from RNA polymerase II promoter in response to zinc deficiency					This term was obsoleted because it represents a GO-CAM model.	GO:0034224|GO:0006357				True			biological_process											owl:Class	
GO:0001129	biolink:NamedThing	obsolete RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly	OBSOLETE. Binding to a member of the class of TATA-binding proteins (TBP), including any of the TBP-related factors (TRFs), to facilitate the aggregation, arrangement and bonding together of proteins on RNA polymerase II promoter DNA to form the transcriptional preinitiation complex (PIC), the formation of which is a prerequisite for transcription by RNA polymerase.	tmpzr1t_l9r_go_relaxed.owl	TATA-binding protein binding RNA polymerase II transcription factor activity involved in preinitiation complex assembly|TBP-class protein binding RNA polymerase II transcription factor activity involved in preinitiation complex assembly	https://github.com/geneontology/go-ontology/issues/16053				The reason for obsoletion is that this concept is partly covered by other concepts in the ontology and usage has been inconsistent.		krc	2011-01-20T02:53:35Z		True			molecular_function											owl:Class	
GO:0052398	biolink:NamedThing	obsolete induction by organism of symbiont phytoalexin production	OBSOLETE. The activation by an organism of the production of phytoalexins as part of the defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	induction by organism of symbiont phytoalexin production|activation by organism of symbiont phytoalexin production					This term was made obsolete because it does not represent a real biological process.					True			biological_process											owl:Class	
GO:0009315	biolink:NamedThing	obsolete drug resistance	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	drug resistance			GO:0009410		This term was made obsolete because 'resistance' implies a phenotype rather than a biological process.					True			biological_process											owl:Class	
GO:0075340	biolink:NamedThing	obsolete negative regulation of growth or development of symbiont during interaction with host	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the increase in size or mass of an organism, or the progression of an organism from an initial condition to a later condition, occurring in, on or near the exterior of its host organism.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of growth or development of symbiont during interaction with host					This term was made obsolete because it contained a conjunction (or).	GO:0044147				True			biological_process											owl:Class	
GO:1990967	biolink:NamedThing	obsolete multi-organism toxin transport	OBSOLETE. The directed movement of a toxin into, out of or within a cell, or between cells where two or more organisms of the same or different species are involved.	tmpzr1t_l9r_go_relaxed.owl	typhoid toxin transport					This term was obsoleted because there is no evidence that this process exists.		bf	2016-06-21T09:01:39Z		True			biological_process											owl:Class	
GO:0009984	biolink:NamedThing	obsolete adenylate forming enzyme activity	OBSOLETE. Catalysis of the reaction: substrate + ATP = substrate-AMP + diphosphate.	tmpzr1t_l9r_go_relaxed.owl	adenylate forming enzyme activity					This term was made obsolete because it does not refer to a specific reaction but rather to a process which results in the formation of AMP.	GO:0046033				True			molecular_function											owl:Class	
GO:0005809	biolink:NamedThing	obsolete Golgi-vacuole transport vesicle	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	Golgi-vacuole transport vesicle					This term was made obsolete as part of a general reorganization of vesicle and vesicle coat terms; its position in the ontology suggested that a new term was required.	GO:0030133				True			cellular_component											owl:Class	
GO:0000989	biolink:NamedThing	obsolete transcription factor activity, transcription factor binding	OBSOLETE. Binding to a specific transcription factor, which may be a single protein or a complex, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well.	tmpzr1t_l9r_go_relaxed.owl	transcription factor binding transcription factor activity	https://github.com/geneontology/go-ontology/issues/16053				The reason for obsoletion is that this concept is partly covered by other concepts in the ontology and usage has been inconsistent.	GO:0140110|GO:0008134	krc	2010-08-10T04:57:43Z		True			molecular_function											owl:Class	
GO:0052232	biolink:NamedThing	obsolete positive aerotaxis on or near other organism involved in symbiotic interaction	OBSOLETE. The directed movement of a motile cell or organism towards a higher concentration of environmental oxygen on or near a second organism, where the two organisms are in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	positive aerotaxis on or near other organism during symbiotic interaction	https://github.com/geneontology/go-ontology/issues/18819				This term was obsoleted because it represents both a process and a location.					True			biological_process											owl:Class	
GO:0042336	biolink:NamedThing	obsolete cuticle development involved in protein-based cuticle molting cycle	OBSOLETE. Synthesis and deposition of a protein-based noncellular, hardened, or membranous secretion from an epithelial sheet, occurring as part of the molting cycle. Examples of this process are found in invertebrate species.	tmpzr1t_l9r_go_relaxed.owl	cuticle biosynthetic process during molting|cuticle synthesis during molting|cuticle development involved in protein-based cuticle molting cycle|cuticle formation during molting|cuticle anabolism during molting					This term was made obsolete because 'protein-based cuticle' is an unnecessary grouping term.	GO:0042338|GO:0042337				True			biological_process											owl:Class	
GO:0075211	biolink:NamedThing	obsolete regulation of transmembrane receptor-mediated cAMP signaling in response to host	OBSOLETE. Any process in which the symbiont organism modulates the frequency, rate or extent of its transmembrane receptor-mediated cAMP signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	regulation of symbiont transmembrane receptor-mediated cAMP signal transduction in response to host|regulation of transmembrane receptor-mediated cAMP signalling in response to host|regulation of transmembrane receptor-mediated cAMP signal transduction in response to host					This term was obsoleted because there is no evidence that this process exists.					True			biological_process											owl:Class	
GO:0052134	biolink:NamedThing	obsolete negative aerotaxis on or near host	OBSOLETE. The directed movement of a motile cell or organism towards a lower concentration of environmental oxygen on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/18819				This term was obsoleted because it represents both a process and a location.					True			biological_process											owl:Class	
GO:0075095	biolink:NamedThing	obsolete negative regulation by host of symbiont signal transduction mediated by G-protein beta subunit	OBSOLETE. Any process in which the host organism stops, prevents, or reduces the frequency, rate or extent of the symbiont signal transduction mediated by G-protein beta subunit. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl						The reason for obsoletion is that there is no evidence that the host can modulate or regulate a symbiont's signal transduction pathway.					True			biological_process											owl:Class	
GO:0051185	biolink:NamedThing	obsolete coenzyme transmembrane transporter activity	OBSOLETE. Enables the transfer of a coenzyme from one side of a membrane to the other. A coenzyme is any of various nonprotein organic cofactors that are required, in addition to an enzyme and a substrate, for an enzymatic reaction to proceed.	tmpzr1t_l9r_go_relaxed.owl	coenzyme transporter activity					1. Making inferences in GO about compounds based on the coenzyme role curated by ChEBI creates relationships that are not always true which violates ontological principles for GO; therefore we will cease making these inferences. 2. It is not meaningful to group transport processes that are not all chemically related by the fact that they may be used as a coenzyme.					True			molecular_function											owl:Class	
GO:0015435	biolink:NamedThing	obsolete ABC-type efflux permease activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	ABC-type efflux permease activity					This term was made obsolete because ABC transporters are a protein family rather than a functional grouping.	GO:0043190|GO:0042626				True			molecular_function											owl:Class	
GO:1903160	biolink:NamedThing	obsolete nickel cation transmembrane transporter activity involved in nickel cation import into cell	OBSOLETE. Any nickel cation transmembrane transporter activity that is involved in nickel cation import into cell.	tmpzr1t_l9r_go_relaxed.owl	zinc, cadmium, cobalt, nickel, lead-efflux ATPase activity involved in nickel cation import into cell|nickel cation transmembrane transporter activity involved in nickel cation import into cell					This term was obsoleted at the TermGenie Gatekeeper stage.		dos	2014-07-09T11:56:33Z		True			molecular_function											owl:Class	
GO:0030815	biolink:NamedThing	obsolete negative regulation of cAMP metabolic process	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate).	tmpzr1t_l9r_go_relaxed.owl	negative regulation of 3',5' cAMP metabolic process|downregulation of cAMP metabolic process|down-regulation of cAMP metabolic process|negative regulation of 3',5' cAMP metabolism|negative regulation of adenosine 3',5'-cyclophosphate metabolic process|down regulation of cAMP metabolic process|negative regulation of cyclic AMP metabolic process|negative regulation of 3',5'-cAMP metabolism|negative regulation of adenosine 3',5'-cyclophosphate metabolism|negative regulation of 3',5'-cAMP metabolic process|negative regulation of cyclic AMP metabolism|negative regulation of cAMP metabolism|inhibition of cAMP metabolic process					The reason for obsoletion is that this term represents the regulation of a signaling pathway, not regulation of metabolism.					True			biological_process											owl:Class	
GO:0042643	biolink:NamedThing	obsolete actomyosin, actin portion	OBSOLETE. The actin part of any complex of actin, myosin, and accessory proteins.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/19570				This term was obsoleted because it corresponds to a gene product, actin.					True			cellular_component											owl:Class	
GO:0104005	biolink:NamedThing	obsolete hijacked molecular function	OBSOLETE. A function that was not selected for in the evolution of an organism, but arises from co-option by another organism, e.g. a human protein used as a virus receptor.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/16741				This term was obsoleted because it was an unnecessary grouping class.		dos	2017-08-04T02:12:09Z		True			molecular_function											owl:Class	
GO:0006387	biolink:NamedThing	obsolete snRNA capping	OBSOLETE. The sequence of enzymatic reactions resulting in the addition of a cap to the 5' end of a nascent snRNA transcript.	tmpzr1t_l9r_go_relaxed.owl	snRNA capping					This term was made obsolete because it has been replaced with a more specific term to describe cap hypermethylation. All RNA polymerase II transcripts receive a 7-methyl-G cap. Then for (at least) small nuclear RNAs (snRNAs) and small nucleolar RNAs (snoRNAs), the 7-methyl-G cap is hypermethylated to become a 2,2,7-trimethylguanosine (TMG) cap.	GO:0036261				True			biological_process											owl:Class	
GO:0044141	biolink:NamedThing	obsolete negative regulation of development of symbiont on or near host surface	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the symbiont's progression from an initial condition to a later condition, on or near the cells or tissues of the host organism.	tmpzr1t_l9r_go_relaxed.owl						The reason for obsoletion is this term represents both a process and a component.		jl	2009-08-04T04:32:18Z		True			biological_process											owl:Class	
GO:0035958	biolink:NamedThing	obsolete regulation of glyoxylate cycle by regulation of transcription from RNA polymerase II promoter	OBSOLETE. Any process that modulates the frequency, rate or extent of the glyoxylate cycle by modulating the frequency, rate or extent of transcription from an RNA polymerase II promoter.	tmpzr1t_l9r_go_relaxed.owl	regulation of glyoxylate bypass by regulation of transcription from RNA polymerase II promoter|regulation of glyoxylate bypass by regulation of transcription from Pol II promoter|regulation of glyoxylate cycle by regulation of transcription from Pol II promoter					This term was obsoleted because it represents a GO-CAM model.		bf			True			biological_process											owl:Class	
GO:0003789	biolink:NamedThing	obsolete actin filament severing activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	actin filament severing activity			GO:0051014		This term was made obsolete because it describes a biological process.					True			molecular_function											owl:Class	
GO:0051436	biolink:NamedThing	obsolete negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of ubiquitin ligase activity that contributes to the mitotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl	anaphase-promoting complex inhibition during mitotic cell cycle|negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle|mitotic anaphase promoting complex inhibition|mitotic APC inhibition|mitotic SCF complex inhibitor|inhibition of ubiquitin ligase activity during mitotic cell cycle|mitotic anaphase promoting complex inhibitor|mitotic anaphase-promoting complex inhibitor|mitotic anaphase-promoting complex inhibition|APC inhibition during mitotic cell cycle|mitotic APC inhibitor|anaphase promoting complex inhibition during mitotic cell cycle|down regulation of ubiquitin ligase activity during mitotic cell cycle|mitotic ubiquitin ligase inhibitor|down-regulation of ubiquitin ligase activity during mitotic cell cycle|downregulation of ubiquitin ligase activity during mitotic cell cycle|negative regulation of ubiquitin ligase activity during mitotic cell cycle	https://github.com/geneontology/go-ontology/issues/15196				This term was obsoleted because it should be captured as a GO-CAM model.					True			biological_process											owl:Class	
GO:2000190	biolink:NamedThing	obsolete negative regulation of regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor					This term was made obsolete because it makes no sense and was added in error.	GO:0030522|GO:0004879|GO:0000122|GO:0030374	rl	2010-10-18T10:02:57Z		True			biological_process											owl:Class	
GO:1900465	biolink:NamedThing	obsolete negative regulation of arginine catabolic process by negative regulation of transcription from RNA polymerase II promoter	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of cellular arginine catabolic process by stopping, preventing, or reducing the frequency, rate or extent of transcription from an RNA polymerase II promoter.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of arginine degradation by negative regulation of transcription from RNA polymerase II promoter|negative regulation of arginine catabolism by negative regulation of transcription from RNA polymerase II promoter|negative regulation of arginine breakdown by negative regulation of transcription from RNA polymerase II promoter					This term was obsoleted because it represents a GO-CAM model.		dgf	2012-05-01T07:38:01Z		True			biological_process											owl:Class	
GO:0004283	biolink:NamedThing	obsolete plasmin activity	OBSOLETE. Catalysis of the preferential cleavage of Lys-Xaa > Arg-Xaa; higher selectivity than trypsin. Converts fibrin into soluble products.	tmpzr1t_l9r_go_relaxed.owl	fibrinase activity|serum tryptase activity|plasmin activity|fibrinolysin activity|actase activity|thrombolysin			GO:0004252		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:1902496	biolink:NamedThing	obsolete protein binding involved in negative regulation of telomere maintenance via telomerase	OBSOLETE. Any protein binding that is involved in negative regulation of telomere maintenance via telomerase.	tmpzr1t_l9r_go_relaxed.owl	protein binding involved in down regulation of telomere maintenance via telomerase activity|protein binding involved in inhibition of telomere maintenance via telomerase|protein binding involved in down-regulation of telomere maintenance via telomerase activity|protein binding involved in downregulation of telomere maintenance via telomerase activity					The reason for obsoletion is that this should be captured as a GO-CAM model.		dph	2013-11-13T16:22:49Z		True			molecular_function											owl:Class	
GO:0001603	biolink:NamedThing	obsolete vasopressin-like receptor activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	vasopressin-like receptor activity										True			molecular_function											owl:Class	
GO:1904740	biolink:NamedThing	obsolete positive regulation of filamentous growth of a population of unicellular organisms in response to starvation by transcription from RNA polymerase II promoter	OBSOLETE. A transcription from RNA polymerase II promoter that results in positive regulation of filamentous growth of a population of unicellular organisms in response to starvation.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of filamentous growth of a population of unicellular organisms in response to starvation by RNA polymerase II transcription factor activity|positive regulation of filamentous growth of a population of unicellular organisms in response to starvation by gene-specific transcription from RNA polymerase II promoter|positive regulation of filamentous growth of a population of unicellular organisms in response to starvation by specific transcription from RNA polymerase II promoter|positive regulation of filamentous growth of a population of unicellular organisms in response to starvation by transcription from Pol II promoter|positive regulation of filamentous growth of a population of unicellular organisms in response to starvation by general transcription from RNA polymerase II promoter					This term was obsoleted because it represents a GO-CAM model.		tb	2015-10-15T21:30:51Z		True			biological_process											owl:Class	
GO:0035980	biolink:NamedThing	obsolete invasive growth in response to nitrogen limitation	OBSOLETE. The growth of colonies in filamentous chains of cells as a result of a reduced availability of nitrogen.	tmpzr1t_l9r_go_relaxed.owl	invasive growth in response to nitrogen limitation					This term was made obsolete because the GO term 'pseudohyphal growth ; GO:0007124' describes growth under nitrogen-limiting conditions.	GO:0007124	bf	2011-08-22T01:20:39Z		True			biological_process											owl:Class	
GO:0071512	biolink:NamedThing	obsolete MAPK import into nucleus involved in conjugation with cellular fusion	OBSOLETE. The directed movement of a MAP kinase to the nucleus that occurs in the context of conjugation with cellular fusion.	tmpzr1t_l9r_go_relaxed.owl	MAPK import into nucleus involved in mating response|nuclear translocation of MAPK involved in conjugation with cellular fusion|nuclear translocation of MAPK involved in mating response|conjugation with cellular fusion, nuclear translocation of MAPK|conjugation with cellular fusion, MAPK import into nucleus					The reason for obsoletion is that this term represents a GO-CAM model.	GO:0006606	mah	2010-01-05T02:11:08Z		True			biological_process											owl:Class	
GO:0030087	biolink:NamedThing	obsolete PSII associated light-harvesting complex II, core complex, LHCIIc subcomplex	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	PSII associated light-harvesting complex II, core complex, LHCIIc subcomplex			GO:0009655		This term was made obsolete because the 'complex' it refers to contains only one gene product.					True			cellular_component											owl:Class	
GO:0051188	biolink:NamedThing	obsolete cofactor biosynthetic process	OBSOLETE. The chemical reactions and pathways resulting in the formation of a cofactor, a substance that is required for the activity of an enzyme or other protein.	tmpzr1t_l9r_go_relaxed.owl	cofactor anabolism|cofactor synthesis|cofactor formation|cofactor biosynthesis					1. Making inferences in GO about compounds based on the cofactor role curated by ChEBI creates relationships that are not always true which violates ontological principles for GO; therefore we will cease making these inferences. 2. It is not meaningful to group metabolic processes that are not all chemically related by the fact that they may be used as a cofactor.					True			biological_process											owl:Class	
GO:0019816	biolink:NamedThing	obsolete B cell receptor accessory molecule complex	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	B cell receptor accessory molecule complex					This term was made obsolete because it represents a molecule and not a location or complex.	GO:0019815				True			cellular_component											owl:Class	
GO:0044034	biolink:NamedThing	obsolete multi-organism biosynthetic process	OBSOLETE. A biosynthetic process - chemical reactions and pathways resulting in the formation of substances - which involves more than one organism.	tmpzr1t_l9r_go_relaxed.owl	multi-organismal biosynthetic process|multi-organism biosynthesis|multi-organismal biosynthesis	https://github.com/geneontology/go-ontology/issues/18787				This term was obsoleted because there is no evidence that this process exists.					True			biological_process											owl:Class	
GO:0035421	biolink:NamedThing	obsolete activation of MAPKK activity involved in innate immune response	OBSOLETE. Any process that initiates the activity of the inactive enzyme MAP kinase kinase in the context of an innate immune response, a defense response mediated by germline encoded components that directly recognize components of potential pathogens.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/18000						bf	2010-03-29T01:26:44Z		True			biological_process											owl:Class	
GO:0003773	biolink:NamedThing	obsolete heat shock protein activity	OBSOLETE. Any of a group of specific proteins that are synthesized by both prokaryotic and eukaryotic cells after they have been exposed to a temperature that is higher than normal. Other stresses, e.g. free radical damage, have a similar effect. Many members of the hsp family are not induced but are present in all cells. They are characterized by their role as molecular chaperones.	tmpzr1t_l9r_go_relaxed.owl	heat shock protein activity					This term was made obsolete because it represents a class of gene products rather than a molecular function.	GO:0006986|GO:0042026				True			molecular_function											owl:Class	
GO:0039572	biolink:NamedThing	obsolete suppression by virus of host STAT2 activity by negative regulation of STAT2 tyrosine phosphorylation	OBSOLETE. Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host STAT2 (signal transducer and activator of transcription-2) activity by stopping, preventing, or reducing the frequency, rate or extent of the introduction of a phosphate group to a tyrosine residue of a STAT2 protein. For example, the measles virus V protein inhibits tyrosine phosphorylation of STAT2, thereby preventing STAT2 activation.	tmpzr1t_l9r_go_relaxed.owl	inhibition by virus of tyrosine phosphorylation of STAT2					The reason for obsoleting this term is that it is too specific. The exact molecular roles of the individual proteins should be captured separately.		bf	2012-03-12T04:53:50Z		True			biological_process											owl:Class	
GO:0050800	biolink:NamedThing	obsolete hydrolase activity, acting on acid anhydrides, acting on GTP, involved in cellular and subcellular movement	OBSOLETE. Catalysis of the hydrolysis of GTP to directly drive the cellular or subcellular transport of a substance.	tmpzr1t_l9r_go_relaxed.owl	hydrolase activity, acting on acid anhydrides, acting on GTP, involved in cellular and subcellular movement					This term was made obsolete because it represents both process and function information.	GO:0006810|GO:0003924				True			molecular_function											owl:Class	
GO:0015472	biolink:NamedThing	obsolete fimbrium-specific chaperone activity	OBSOLETE. Assists in the correct assembly of fimbria, extracellular organelles that are used to attach a bacterial cell to a surface, but is not a component of the fimbrium when performing its normal biological function.	tmpzr1t_l9r_go_relaxed.owl	fimbrium-specific chaperone activity					This term was made obsolete because it refers to a class of proteins and a biological process rather than a molecular function.	GO:0009297|GO:0051082|GO:0044183|GO:0030674				True			molecular_function											owl:Class	
GO:1903163	biolink:NamedThing	obsolete sodium ion transmembrane transporter activity involved in sodium ion import into cell	OBSOLETE. Any sodium ion transmembrane transporter activity that is involved in sodium ion import into cell.	tmpzr1t_l9r_go_relaxed.owl	sodium ion transmembrane transporter activity involved in sodium ion import into cell|sodium transporter activity involved in sodium ion import into cell					This term was obsoleted at the TermGenie Gatekeeper stage.		dos	2014-07-09T11:56:49Z		True			molecular_function											owl:Class	
GO:0005941	biolink:NamedThing	obsolete unlocalized protein complex	OBSOLETE. Used as a holding place for cellular components whose precise localization is, as yet, unknown, or has not been determined by GO (the latter is the major reason for nodes to have this parent); this term should not be used for annotation of gene products.	tmpzr1t_l9r_go_relaxed.owl	unlocalized protein complex					This term was made obsolete because it was originally intended only as a temporary parent for protein complex terms for which no more specific parents had been found. This term no longer has any children: All protein complex terms are is_a 'protein complex ; GO:0043234' and nearly all have been placed under parents to yield more specific paths traversing a part_of relationship. In other words, the term has been superseded by other terms and relationships in the cellular component ontology, and is no longer needed.					True			cellular_component											owl:Class	
GO:0090620	biolink:NamedThing	obsolete APC-Cdc20 complex	OBSOLETE. An anaphase promoting complex bound to the fizzy family APC activator Cdc20/Slp1 which regulates the metaphase anaphase transition by activating the APC/C to target the anaphase inhibitor securin and promotes sister chromatid separation.	tmpzr1t_l9r_go_relaxed.owl	mitotic anaphase promotic complex|APC-fizzy complex|APC-Slp1 complex					This term was made obsolete because it is too fine-grained for GO. Consider Complex Portal EBI-1252490, Anaphase-Promoting Complex variant 2 as an alternate term.	GO:0005680	tb	2014-12-17T17:01:38Z		True			cellular_component											owl:Class	
GO:1901313	biolink:NamedThing	obsolete positive regulation of gene expression involved in extracellular matrix organization	OBSOLETE. Any process that activates or increases the frequency, rate or extent of gene expression involved in extracellular matrix organization.	tmpzr1t_l9r_go_relaxed.owl	activation of gene expression involved in extracellular matrix organization|up regulation of gene expression involved in extracellular matrix organization|up-regulation of extracellular matrix protein production|upregulation of gene expression involved in extracellular matrix organization|activation of expression of extracellular matrix proteins|up regulation of expression of extracellular matrix proteins|up regulation of extracellular matrix protein production|upregulation of expression of extracellular matrix proteins|up-regulation of expression of extracellular matrix proteins|upregulation of extracellular matrix protein production|positive regulation of expression of extracellular matrix proteins|activation of extracellular matrix protein production|up-regulation of gene expression involved in extracellular matrix organization|positive regulation of extracellular matrix protein production					This term was made obsolete is that in these terms the 'involved in' process is not truly involved_in (i.e. part_of) the process but instead is causally upstream of it. We advise replacing annotations to these terms with annotations + extensions using the causally_upstream_of relation e.g. P1234 regulation of gene expression [causally_upstream_of] extracellular matrix organization.	GO:0010628	vk	2012-08-22T09:18:42Z		True			biological_process											owl:Class	
GO:0052402	biolink:NamedThing	obsolete induction by organism of symbiont resistance gene-dependent defense response	OBSOLETE. The activation by an organism of the resistance gene-dependent defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	induction by organism of defense response in symbiont by specific elicitors|activation by organism of symbiont gene-for-gene resistance|activation by organism of defense response in symbiont by specific elicitors|induction by organism of symbiont resistance gene-dependent defense response|induction by organism of pathogen-race/symbiont plant cultivar-specific resistance in symbiont|activation by organism of pathogen-race/symbiont plant cultivar-specific resistance in symbiont|activation by organism of symbiont resistance gene-dependent defense response|induction by organism of symbiont gene-for-gene resistance					This term was made obsolete because it does not represent a real biological process.					True			biological_process											owl:Class	
GO:0009377	biolink:NamedThing	obsolete HslUV protease activity	OBSOLETE. Catalysis of the ATP-dependent hydrolysis of peptide bonds in substrates including E. coli SulA and misfolded proteins.	tmpzr1t_l9r_go_relaxed.owl	HslUV protease activity			GO:0008233		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:1900013	biolink:NamedThing	obsolete cellular response to potassium ion involved in chemotaxis to cAMP	OBSOLETE. The directed movement of a motile cell in response to the presence of 3',5'-cAMP that results in a change in state or activity (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a potassium ion stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to K+ ion of chemotaxis to 3',5'-cAMP|cellular response to K+ ion of chemotaxis to cyclic AMP|cellular response to potassium of chemotaxis to 3',5' cAMP|cellular response to potassium ion of chemotaxis to cAMP|cellular response to potassium ion of chemotaxis to 3',5' cAMP|cellular response to potassium of chemotaxis to adenosine 3',5'-cyclophosphate|cellular response to potassium of chemotaxis to 3',5'-cAMP|cellular response to potassium ion involved in chemotaxis to cAMP|cellular response to potassium ion of chemotaxis to cyclic AMP|cellular response to K+ ion of chemotaxis to 3',5' cAMP|cellular response to potassium ion of chemotaxis to 3',5'-cAMP|cellular response to K+ ion of chemotaxis to cAMP|cellular response to potassium ion of chemotaxis to adenosine 3',5'-cyclophosphate|cellular response to potassium of chemotaxis to cyclic AMP|cellular response to K+ ion of chemotaxis to adenosine 3',5'-cyclophosphate|cellular response to potassium of chemotaxis to cAMP					This term was made obsolete because it was added by mistake.		pr	2012-01-11T07:59:57Z		True			biological_process											owl:Class	
GO:0004207	biolink:NamedThing	obsolete effector caspase activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	effector caspase activity			GO:0004197		This term was made obsolete because it includes biological process information.	GO:0006915				True			molecular_function											owl:Class	
GO:1901636	biolink:NamedThing	obsolete negative regulation of maintenance of presynaptic active zone structure	OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of maintenance of presynaptic active zone structure.	tmpzr1t_l9r_go_relaxed.owl	inhibition of maintenance of presynaptic active zone structure|down-regulation of maintenance of presynaptic active zone structure|negative regulation of maintenance of presynaptic active zone structure|down regulation of maintenance of presynaptic active zone structure|downregulation of maintenance of presynaptic active zone structure					This term was obsoleted at the TermGenie Gatekeeper stage.		ans	2012-11-15T14:17:07Z		True			biological_process											owl:Class	
GO:1900014	biolink:NamedThing	obsolete cellular response to calcium ion involved in chemotaxis to cAMP	OBSOLETE. The directed movement of a motile cell in response to the presence of 3',5'-cAMP that results in a change in state or activity (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a calcium ion stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to calcium ion involved in chemotaxis to cAMP|cellular response to Ca2+ ion of chemotaxis to 3',5' cAMP|cellular response to Ca2+ ion of chemotaxis to 3',5'-cAMP|cellular response to Ca2+ ion of chemotaxis to cyclic AMP|cellular response to Ca2+ ion of chemotaxis to adenosine 3',5'-cyclophosphate|cellular response to calcium ion of chemotaxis to 3',5' cAMP|cellular response to calcium ion of chemotaxis to cAMP|cellular response to Ca2+ ion of chemotaxis to cAMP|cellular response to calcium ion of chemotaxis to adenosine 3',5'-cyclophosphate|cellular response to calcium ion of chemotaxis to cyclic AMP|cellular response to calcium ion of chemotaxis to 3',5'-cAMP							pr	2012-01-11T08:06:58Z		True			biological_process											owl:Class	
GO:0015465	biolink:NamedThing	obsolete lysin activity	OBSOLETE. An agent that can lyse cells.	tmpzr1t_l9r_go_relaxed.owl	lysin activity					This term was made obsolete because it represents a class of gene products.	GO:0019835				True			molecular_function											owl:Class	
GO:0061397	biolink:NamedThing	obsolete positive regulation of transcription from RNA polymerase II promoter in response to copper ion	OBSOLETE. Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter in response to an copper ion stimulus.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it represents a GO-CAM model.	GO:0045944|GO:0071280	dph	2012-01-10T09:14:51Z		True			biological_process											owl:Class	
GO:0001871	biolink:NamedThing	obsolete pattern binding	OBSOLETE. Binding to a repeating or polymeric structure, such as a polysaccharide or peptidoglycan.	tmpzr1t_l9r_go_relaxed.owl	pattern recognition activity					This term was obsoleted because it was an unnecessary grouping term.					True			molecular_function											owl:Class	
GO:0021882	biolink:NamedThing	obsolete regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment	OBSOLETE. Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the commitment of a neuroblast to a neuronal fate. The neuron will reside in the forebrain.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it represents a GO-CAM model.	GO:0021877|GO:0006357				True			biological_process											owl:Class	
GO:0004287	biolink:NamedThing	obsolete prolyl oligopeptidase activity	OBSOLETE. Catalysis of the hydrolysis of Pro-Xaa > Ala-Xaa in oligopeptides.	tmpzr1t_l9r_go_relaxed.owl	post-proline endopeptidase activity|prolyl oligopeptidase activity|proline endopeptidase activity|prolyl endopeptidase activity|endoprolylpeptidase activity|post-proline cleaving enzyme activity|proline-specific endopeptidase activity			GO:0004252		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0005481	biolink:NamedThing	obsolete vesicle fusion	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	vesicle fusion					This term was made obsolete because it represents a biological process and not a molecular function.	GO:0016192|GO:0019817|GO:0006906|GO:0007086|GO:0016189				True			molecular_function											owl:Class	
GO:0033667	biolink:NamedThing	obsolete negative regulation of growth or development of symbiont in host	OBSOLETE. Any process by which the symbiont stops, prevents or reduces its increase in size or mass or its progression from an initial condition to a later condition, within the cells or tissues of the host organism. The host is defined as the larger of the organisms involved in the symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	downregulation of growth or development of organism within host|down-regulation of growth or development of organism within host|negative regulation of growth or development of symbiont in host|negative regulation of growth or development of symbiont within host|negative regulation of invasive growth|inhibition of growth of development of organism within host|down regulation of growth or development of organism within host					This term was made obsolete because it contained a conjunction (or).	GO:0044131				True			biological_process											owl:Class	
GO:0015023	biolink:NamedThing	obsolete syndecan	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	syndecan					This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0070020	biolink:NamedThing	obsolete transforming growth factor beta1-type II receptor complex	OBSOLETE. A protein complex that consists of a dimeric transforming growth factor beta (TGF-beta) type II receptor bound to a TGF-beta1 dimer.	tmpzr1t_l9r_go_relaxed.owl	TGF-beta1-type II receptor complex|TGF-beta receptor II-TGF-beta1 complex	https://github.com/geneontology/go-ontology/issues/12676				This term was made obsolete because it does not represent a physiological complex.					True			cellular_component											owl:Class	
GO:0100005	biolink:NamedThing	obsolete positive regulation of ethanol catabolic process by transcription from RNA polymerase II promoter	OBSOLETE. Any transcription from RNA polymerase II promoter process that positively regulates ethanol catabolic process.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it represents a GO-CAM model.		cjm	2015-04-02T04:13:19Z		True			biological_process											owl:Class	
GO:0046237	biolink:NamedThing	obsolete phenanthrene biosynthetic process	OBSOLETE. The chemical reactions and pathways resulting in the formation of phenanthrene, a tricyclic aromatic hydrocarbon.	tmpzr1t_l9r_go_relaxed.owl	phenanthrene biosynthesis|phenanthrene formation|phenanthrene anabolism|phenanthrene synthesis|phenanthrene biosynthetic process			GO:0018955		This term was made obsolete because phenanthrene is not synthesized by living organisms, and GO does not cover non-biological processes.					True			biological_process											owl:Class	
GO:0035286	biolink:NamedThing	obsolete leg segmentation	OBSOLETE. Division of a leg into a series of semi-repetitive parts or segments. Most arthropod appendages are visibly segmented; the Drosophila leg for example has nine segments, each separated from the next by a flexible joint.	tmpzr1t_l9r_go_relaxed.owl	leg segmentation					This term was made obsolete because leg is a mechano-functional grouping, and having both 'leg morphogenesis' and 'hindlimb morphogenesis' terms causes errors in querying.	GO:0035285|GO:0036011				True			biological_process											owl:Class	
GO:0031940	biolink:NamedThing	obsolete positive regulation of chromatin silencing at telomere	OBSOLETE. Any process that activates or increases the frequency, rate or extent of chromatin silencing at telomeres.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of heterochromatic silencing at telomere|up regulation of chromatin silencing at telomere|activation of chromatin silencing at telomere|upregulation of chromatin silencing at telomere|up-regulation of chromatin silencing at telomere|stimulation of chromatin silencing at telomere	https://github.com/geneontology/go-ontology/issues/22027				This term was obsoleted because there is no evidence that chromatin silencing /heterochromatin assembly are directly regulated.					True			biological_process											owl:Class	
GO:1990750	biolink:NamedThing	obsolete axon shaft	OBSOLETE. Main portion of an axon, excluding terminal, spines, or dendrites.	tmpzr1t_l9r_go_relaxed.owl	axonal shaft					This term was made obsolete because it was added in error.	GO:0044304	sl	2015-05-21T17:46:18Z		True			cellular_component											owl:Class	
GO:0030319	biolink:NamedThing	obsolete cellular di-, tri-valent inorganic anion homeostasis	OBSOLETE. Any process involved in the maintenance of an internal steady state of divalent or trivalent inorganic anions at the level of a cell.	tmpzr1t_l9r_go_relaxed.owl	cellular di-, tri-valent inorganic anion homeostasis					This term was made obsolete because it has been split.	GO:0072501|GO:0072502				True			biological_process											owl:Class	
GO:0072694	biolink:NamedThing	obsolete cell cycle arrest in response to caffeine	OBSOLETE. The cell cycle regulatory process in which the cell cycle is halted during one of the normal phases (G1, S, G2, M) as a result of a caffeine stimulus.	tmpzr1t_l9r_go_relaxed.owl						This term was made obsolete because it does not represent a real process.		mah	2011-12-05T01:29:00Z		True			biological_process											owl:Class	
GO:0017078	biolink:NamedThing	obsolete Hsc70 protein regulator activity	OBSOLETE. Binds to and modulates the activity of the molecular chaperone Hsc70.	tmpzr1t_l9r_go_relaxed.owl	Hsc70 interacting protein|Hsc70 protein regulator activity			GO:0031072		This term was made obsolete because it refers to a non-existent molecular function term, 'Hsp70 protein activity'.	GO:0051082|GO:0006457|GO:0051787				True			molecular_function											owl:Class	
GO:0000739	biolink:NamedThing	obsolete DNA strand annealing activity	OBSOLETE. Facilitates the base-pairing of complementary single-stranded DNA.	tmpzr1t_l9r_go_relaxed.owl	DNA strand annealing activity					This term was made obsolete because it describes a process and not an activity.	GO:0036292|GO:0036310				True			molecular_function											owl:Class	
GO:0015982	biolink:NamedThing	obsolete antiport	OBSOLETE. The process of coupled solute translocation in which two solutes equilibrate across an osmotic barrier, the translocation of solute being coupled to the translocation of the other in the opposite direction.	tmpzr1t_l9r_go_relaxed.owl	antiport			GO:0015297		This term was made obsolete because it represents a molecular function rather than a biological process.					True			biological_process											owl:Class	
GO:1902887	biolink:NamedThing	obsolete positive regulation of proteasome-activating ATPase activity	OBSOLETE. Any process that activates or increases the frequency, rate or extent of proteasome-activating ATPase activity.	tmpzr1t_l9r_go_relaxed.owl	upregulation of proteasome-activating ATPase activity|up regulation of proteasome channel gating activity|positive regulation of ATPase involved in positive regulation of proteasomal protein catabolic process|up-regulation of proteasome channel opening activity|up-regulation of proteasomal ATPase activity|activation of proteasome channel gating activity|activation of proteasome-activating ATPase activity|upregulation of proteasome channel gating activity|up regulation of proteasomal ATPase activity|positive regulation of proteasomal ATPase activity|positive regulation of proteasome channel opening activity|up regulation of ATPase involved in positive regulation of proteasomal protein catabolic process|upregulation of ATPase involved in positive regulation of proteasomal protein catabolic process|up-regulation of ATPase involved in positive regulation of proteasomal protein catabolic process|activation of proteasome channel opening activity|up-regulation of proteasome-activating ATPase activity|up regulation of proteasome channel opening activity|up regulation of proteasome-activating ATPase activity|activation of proteasomal ATPase activity|upregulation of proteasome channel opening activity|upregulation of proteasomal ATPase activity|positive regulation of proteasome channel gating activity|up-regulation of proteasome channel gating activity|activation of ATPase involved in positive regulation of proteasomal protein catabolic process	https://github.com/geneontology/go-ontology/issues/20879				This term was obsoleted because it represents a molecular function.		di	2014-04-04T17:35:36Z		True			biological_process											owl:Class	
GO:1905926	biolink:NamedThing	obsolete positive regulation of invadopodium assembly	OBSOLETE. Any process that activates or increases the frequency, rate or extent of invadopodium assembly.	tmpzr1t_l9r_go_relaxed.owl	activation of invadopodium formation|positive regulation of invadopodium formation|up-regulation of invadopodium formation|up regulation of invadopodium assembly|activation of invadopodium assembly|upregulation of invadopodium assembly|up regulation of invadopodium formation|upregulation of invadopodium formation|up-regulation of invadopodium assembly					This term was made obsolete because an invadopodium is an abnormal structure found in cancerous or transformed cells that is out of scope of GO.		sl	2017-02-08T21:38:48Z		True			biological_process											owl:Class	
GO:0022867	biolink:NamedThing	obsolete transmembrane 2-electron transfer carrier	OBSOLETE. Enables transfer of two electrons across a membrane.	tmpzr1t_l9r_go_relaxed.owl	transmembrane two-electron transfer carrier					The reason for obsoletion is that the term does not represent a molecular function but rather a process.					True			molecular_function											owl:Class	
GO:0030807	biolink:NamedThing	obsolete positive regulation of cyclic nucleotide catabolic process	OBSOLETE. Any process that activates or increases the frequency, rate or extent of chemical reactions and pathways resulting in the breakdown of cyclic nucleotides.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of cyclic nucleotide catabolism|up regulation of cyclic nucleotide catabolic process|positive regulation of cyclic nucleotide degradation|positive regulation of cyclic nucleotide breakdown|up-regulation of cyclic nucleotide catabolic process|stimulation of cyclic nucleotide catabolic process|upregulation of cyclic nucleotide catabolic process|activation of cyclic nucleotide catabolic process					The reason for obsoletion is that this term represents the regulation of a signaling pathway, not regulation of metabolism.					True			biological_process											owl:Class	
GO:0016658	biolink:NamedThing	obsolete oxidoreductase activity, acting on NADH or NADPH, flavin as acceptor	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	oxidoreductase activity, acting on NADH or NADPH, flavin as acceptor					This term was made obsolete because it was a grouping term taken from EC that no longer has any functions associated with it.	GO:0008752|GO:0042602				True			molecular_function											owl:Class	
GO:0023068	biolink:NamedThing	obsolete signal transmission via phloem	OBSOLETE. The process in which a signal is conveyed via the phloem.	tmpzr1t_l9r_go_relaxed.owl	signal transmission via phloem					This term was made obsolete because the meaning of the term is ambiguous.	GO:0023052|GO:0010233		2010-02-16T09:30:50Z		True			biological_process											owl:Class	
GO:0017029	biolink:NamedThing	obsolete lysosomal protein stabilization	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	lysosomal protein stabilization					This term was made obsolete because it contains both component and function information.	GO:0005764|GO:0050821				True			molecular_function											owl:Class	
GO:0097756	biolink:NamedThing	obsolete negative regulation of blood vessel diameter	OBSOLETE. Any process that decreases the diameter of blood vessels.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of vasodilation					This term was obsoleted because it corresponded to an existing term, GO:0042310 ; vasocontriction.		pr	2017-02-08T15:36:16Z		True			biological_process											owl:Class	
GO:0071343	biolink:NamedThing	obsolete negative regulation of establishment of actomyosin contractile ring localization	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the process in which a contractile ring is assembled in a specific location.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of establishment of contractile ring localization involved in cell cycle cytokinesis|negative regulation of establishment of contractile ring localization involved in cytokinesis during cell cycle|negative regulation of establishment of contractile ring localisation involved in cell cycle cytokinesis|negative regulation of establishment of actomyosin contractile ring localization					This term was made obsolete because it does not describe a wild-type or normal process.		mah	2009-12-11T01:33:14Z		True			biological_process											owl:Class	
GO:0061404	biolink:NamedThing	obsolete positive regulation of transcription from RNA polymerase II promoter in response to increased salt	OBSOLETE. Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of detection of, or exposure to, an increase in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/12739				This term was obsoleted because it represents a GO-CAM model.	GO:0071472|GO:0045944	dph	2012-01-10T03:20:40Z		True			biological_process											owl:Class	
GO:0007468	biolink:NamedThing	obsolete regulation of rhodopsin gene expression	OBSOLETE. Any process that modulates the frequency, rate or extent of rhodopsin gene expression. This includes transcriptional, translational, or posttranslational regulation.	tmpzr1t_l9r_go_relaxed.owl	regulation of rhodopsin gene activity					This term was obsoleted because it referes to a specific gene product. The gene product should be captured as an annotation extension using 'has input'.	GO:0006357				True			biological_process											owl:Class	
GO:0004898	biolink:NamedThing	obsolete gp130	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	gp130					This term was made obsolete because it represents a gene product.	GO:0004915|GO:0004897|GO:0004921				True			molecular_function											owl:Class	
GO:0045783	biolink:NamedThing	obsolete negative regulation of calcium in ER	OBSOLETE. Any process that reduces the concentration of calcium in the ER.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of calcium in ER					This term was made obsolete because the term name is ambiguous and as a result, the term was incorrectly placed in the ontology (it was a descendant of 'protein transport').	GO:0006874|GO:0005783				True			biological_process											owl:Class	
GO:0005660	biolink:NamedThing	obsolete delta-DNA polymerase cofactor complex	OBSOLETE. A complex of proteins that interacts with delta-DNA polymerase, promoting elongation. In humans it is a heteropentamer of subunits of 140/145, 40, 38, 37 and 36.5 kDa, which form a complex with the proliferating cell nuclear antigen (PCNA) in the presence of ATP.	tmpzr1t_l9r_go_relaxed.owl	delta DNA polymerase cofactor complex|delta-DNA polymerase cofactor complex					This term was made obsolete because it refers to two distinct complexes, PCNA and Replication factor C (RFC), the latter of which is already represented as a separate, unrelated GO term (DNA replication factor C complex ; GO:0005663). In addition, the phrase 'delta-DNA polymerase cofactor' to represent both PCNA and RFC is not used in current literature.	GO:0005663|GO:0043626				True			cellular_component											owl:Class	
GO:0075091	biolink:NamedThing	obsolete positive regulation by host of symbiont signal transduction mediated by G-protein alpha subunit	OBSOLETE. Any process in which the host organism activates, maintains or increases the frequency, rate or extent of the symbiont signal transduction mediated by G-protein alpha subunit. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl						The reason for obsoletion is that there is no evidence that the host can modulate or regulate a symbiont's signal transduction pathway.					True			biological_process											owl:Class	
GO:0039575	biolink:NamedThing	obsolete suppression by virus of host TYK2 activity by negative regulation of TYK2 tyrosine phosphorylation	OBSOLETE. Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host TYK2 (tyrosine kinase 2) activity by stopping, preventing or reducing phosphorylation and thereby activation of TYK2.	tmpzr1t_l9r_go_relaxed.owl	inhibition by virus of host TYK2 phosphorylation|inhibition by virus of host TYK2 activation					The reason for obsoleting this term is that it is too specific. The exact molecular roles of the individual proteins should be captured separately.		bf			True			biological_process											owl:Class	
GO:0010504	biolink:NamedThing	obsolete regulation of cell cycle arrest in response to nitrogen starvation	OBSOLETE. Any process that modulates the frequency, rate or extent of cell cycle arrest in response to nitrogen starvation.	tmpzr1t_l9r_go_relaxed.owl						This term was made obsolete because it is superfluous, as only the more specific 'mitotic G1 cell cycle arrest in response to nitrogen starvation' has been observed.					True			biological_process											owl:Class	
GO:0044134	biolink:NamedThing	obsolete development of symbiont on or near host phyllosphere	OBSOLETE. The progression of the symbiont from an initial condition to a later condition, occurring on or near its host phyllosphere. The host phyllosphere is defined as total above-ground surfaces of a plant as a habitat for symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl						The reason for obsoletion is this term represents both a process and a component.		jl	2009-08-04T04:10:58Z		True			biological_process											owl:Class	
GO:0035419	biolink:NamedThing	obsolete activation of MAPK activity involved in innate immune response	OBSOLETE. Any process that initiates the activity of the inactive enzyme MAP kinase in the context of an innate immune response, a defense response mediated by germline encoded components that directly recognize components of potential pathogens.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/18000				This term was obsoleted because it should be represented as a GO-CAM model.		bf	2010-03-29T01:25:24Z		True			biological_process											owl:Class	
GO:0004232	biolink:NamedThing	obsolete interstitial collagenase activity	OBSOLETE. Catalysis of the preferential cleavage of one bond in native collagen. Cleavage of the triple helix of collagen at about three-quarters of the length of the molecule from the N-terminus, at Gly775-Ile776 in the alpha-1(I) chain. Cleaves synthetic substrates and alpha-macroglobulins at bonds where P1' is a hydrophobic residue.	tmpzr1t_l9r_go_relaxed.owl	matrix metalloproteinase 1|interstitial collagenase activity|vertebrate collagenase activity|MMP-1			GO:0004252		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0004230	biolink:NamedThing	obsolete glutamyl aminopeptidase activity	OBSOLETE. Catalysis of the release of a N-terminal glutamate (and to a lesser extent aspartate) from a peptide.	tmpzr1t_l9r_go_relaxed.owl	L-aspartate aminopeptidase activity|aspartate aminopeptidase activity|glutamyl peptidase activity|membrane aminopeptidase II|Ca2+-activated glutamate aminopeptidase activity|aminopeptidase A|angiotensinase A2|antigen BP-1/6C3 of mouse B lymphocytes|angiotensinase A|glutamyl aminopeptidase activity				MetaCyc:3.4.11.7-RXN|EC:3.4.11.7	This term was made obsolete because it represents a gene product.	GO:0004177|GO:0008235				True			molecular_function											owl:Class	
GO:0044460	biolink:NamedThing	obsolete flagellum part	OBSOLETE. Any constituent part of a flagellum, a long whiplike or feathery structure borne either singly or in groups by the motile cells of many bacteria and unicellular eukaryotes and by the motile male gametes of many eukaryotic organisms, which propel the cell through a liquid medium.	tmpzr1t_l9r_go_relaxed.owl	flagellum component|flagellum part					This term was made obsolete because it was an unnecessary grouping term. Eukaryotic flagella were deemed to be equivalent to cilia and merged, so the only remaining child to this term was 'bacterial-type flagellum part ; GO:0044461'.					True			cellular_component											owl:Class	
GO:0003969	biolink:NamedThing	obsolete RNA editase activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	RNA editase activity					This term was made obsolete because it describes a biological process.					True			molecular_function											owl:Class	
GO:1901488	biolink:NamedThing	obsolete positive regulation of SREBP signaling pathway by negative regulation of transcription factor catabolic process	OBSOLETE. Negative regulation of transcription factor catabolism that results in positive regulation of the SREBP signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of SREBP-mediated signalling pathway by negative regulation of transcription factor catabolic process|positive regulation of SREBP signaling pathway by negative regulation of SREBP degradation|positive regulation of SREBP signaling pathway by inhibition of SREBP degradation|positive regulation of SREBP-mediated signaling pathway by negative regulation of transcription factor catabolic process|positive regulation of SREBP signaling pathway by negative regulation of transcription factor catabolism					The reason for obsoletion is that this term should be represented by a GO-CAM model.		bf	2012-10-09T08:23:43Z		True			biological_process											owl:Class	
GO:0016970	biolink:NamedThing	obsolete hemocyanin	OBSOLETE. A blue, copper-containing oxygen carrier present in many molluscs and arthropods.	tmpzr1t_l9r_go_relaxed.owl	hemocyanin			GO:0005344		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0008567	biolink:NamedThing	obsolete dynein ATPase activity	OBSOLETE. Catalysis of the reaction: ATP + H2O = ADP + phosphate. The hydrolysis of ATP by dynein that provides the energy for the movement of organelles (endosomes, lysosomes, mitochondria) along microtubules to the centrosome.	tmpzr1t_l9r_go_relaxed.owl	dynein ATPase activity					This term was made obsolete because it represents a class of gene products, and its definition incorporates process information.	GO:0007018|GO:0003777				True			molecular_function											owl:Class	
GO:1903148	biolink:NamedThing	obsolete uracil transmembrane transporter activity involved in uracil import into cell	OBSOLETE. Any uracil transmembrane transporter activity that is involved in uracil import into cell.	tmpzr1t_l9r_go_relaxed.owl	uracil/uridine permease activity involved in uracil import into cell|uracil transmembrane transporter activity involved in uracil import into cell					This term was obsoleted at the TermGenie Gatekeeper stage.		dos	2014-07-09T11:55:24Z		True			molecular_function											owl:Class	
GO:0090690	biolink:NamedThing	obsolete heteroreceptor complex	OBSOLETE. A receptor complex that consists of two or more different receptor complexes that individually undergo combination with a hormone, neurotransmitter, drug or intracellular messenger. The formation of the higher level complex initiates a change in cell function.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted as it was created in error.		tb	2016-08-24T09:47:15Z		True			cellular_component											owl:Class	
GO:1905928	biolink:NamedThing	obsolete negative regulation of invadopodium disassembly	OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of invadopodium disassembly.	tmpzr1t_l9r_go_relaxed.owl	down regulation of invadopodium disassembly|inhibition of invadopodium disassembly|down-regulation of invadopodium disassembly|downregulation of invadopodium disassembly					This term was made obsolete because an invadopodium is an abnormal structure found in cancerous or transformed cells that is out of scope of GO.		sl	2017-02-08T21:39:05Z		True			biological_process											owl:Class	
GO:0008130	biolink:NamedThing	obsolete neutrophil collagenase activity	OBSOLETE. Catalysis of the cleavage of interstitial collagens in the triple helical domain. Unlike EC:3.4.24.7, this enzyme cleaves type III collagen more slowly than type I.	tmpzr1t_l9r_go_relaxed.owl	matrix metalloproteinase 8 activity|neutrophil collagenase activity|MMP-8|PMNL collagenase activity			GO:0004252		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:1990365	biolink:NamedThing	obsolete response to phenol	OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of phenols.	tmpzr1t_l9r_go_relaxed.owl	response to phenol					This term was obsoleted at the TermGenie Gatekeeper stage.		tt	2014-04-23T22:20:00Z		True			biological_process											owl:Class	
GO:0100027	biolink:NamedThing	obsolete regulation of cell separation after cytokinesis by transcription from RNA polymerase II promoter	OBSOLETE. Any transcription from RNA polymerase II promoter process that regulates cell separation after cytokinesis.	tmpzr1t_l9r_go_relaxed.owl								cjm	2015-04-02T04:13:19Z		True			biological_process											owl:Class	
GO:0018179	biolink:NamedThing	obsolete peptidyl-cysteine desulfurization	OBSOLETE. The desulfurization of peptidyl-L-cysteine to yield L-alanine and elemental sulfur; peptidyl-L-cysteine persulfide is an intermediate.	tmpzr1t_l9r_go_relaxed.owl	peptidyl-cysteine desulphurization|peptidyl-cysteine desulfurization				RESID:AA0269	This term was made obsolete because to does not correspond to a real process.					True			biological_process											owl:Class	
GO:1900446	biolink:NamedThing	obsolete negative regulation of tRNA transcription from RNA polymerase III promoter	OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of tRNA transcription from RNA polymerase III promoter.	tmpzr1t_l9r_go_relaxed.owl	downregulation of tRNA transcription from RNA polymerase III promoter|inhibition of tRNA transcription from Pol III promoter|down regulation of tRNA transcription from RNA polymerase III promoter|down regulation of tRNA transcription from Pol III promoter|downregulation of tRNA transcription from Pol III promoter|inhibition of tRNA transcription from RNA polymerase III promoter|negative regulation of tRNA transcription from Pol III promoter|down-regulation of tRNA transcription from RNA polymerase III promoter|down-regulation of tRNA transcription from Pol III promoter					The reason for obsoletion is that there is no specific regulator for negatively regulating tRNA transcription which is separable from general negative regulation of transcription from RNA polymerase III.		sart	2012-04-26T05:28:34Z		True			biological_process											owl:Class	
GO:0051419	biolink:NamedThing	obsolete nebulin binding	OBSOLETE. Binding to nebulin, a large protein (approximately 800kD) that is anchored at the Z-disc by its C-terminal region and spans the length of the thin filament, ending at the edge of the H-zone.	tmpzr1t_l9r_go_relaxed.owl	nebulin binding			GO:0008092		This term was made obsolete because it represents binding to an individual protein.					True			molecular_function											owl:Class	
GO:0052226	biolink:NamedThing	obsolete biosynthesis of substance in other organism involved in symbiotic interaction	OBSOLETE. The chemical reactions and pathways performed by an organism in a second organism resulting in the formation of substances, where the two organisms are in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	biosynthesis of substance in other organism during symbiotic interaction	https://github.com/geneontology/go-ontology/issues/18787				This term was obsoleted because there is no evidence that this process exists.					True			biological_process											owl:Class	
GO:0006922	biolink:NamedThing	obsolete cleavage of lamin involved in execution phase of apoptosis	OBSOLETE. The proteolytic degradation of lamins during apoptosis, leading to the irreversible breakdown of the nuclear lamina.	tmpzr1t_l9r_go_relaxed.owl	cleavage of lamin|cleavage of lamin involved in execution phase of apoptosis					This term was obsoleted because it refers to targets of effector proteins (caspases); the 'cleavage' process referred to in the term name is in fact the same molecular function represented by GO:0097200 'cysteine-type endopeptidase activity involved in execution phase of apoptosis'.	GO:0097200				True			biological_process											owl:Class	
GO:0075093	biolink:NamedThing	obsolete modulation by host of symbiont signal transduction mediated by G-protein beta subunit	OBSOLETE. Any process in which the host organism modulates the frequency, rate or extent of the symbiont signal transduction mediated by G-protein beta subunit. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl						The reason for obsoletion is that there is no evidence that the host can modulate or regulate a symbiont's signal transduction pathway.					True			biological_process											owl:Class	
GO:1905482	biolink:NamedThing	obsolete cytoplasmic sequestering of protein involved in G2 DNA damage checkpoint	OBSOLETE. Any cytoplasmic sequestering of protein that is involved in G2 DNA damage checkpoint.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it represents a GO-CAM model.		vw	2016-09-22T18:23:55Z		True			biological_process											owl:Class	
GO:0008498	biolink:NamedThing	obsolete phospholipid scrambling	OBSOLETE. The trans-bilayer migration of phospholipids accelerated by a phospholipid scramblase upon binding calcium ions.	tmpzr1t_l9r_go_relaxed.owl	phospholipid scrambling			GO:0017121		This term was made obsolete because it represents a biological process and not a molecular function.					True			molecular_function											owl:Class	
GO:0006609	biolink:NamedThing	obsolete mRNA-binding (hnRNP) protein import into nucleus	OBSOLETE. The directed movement of a heterogeneous nuclear ribonucleoprotein from the cytoplasm into the nucleus, across the nuclear membrane.	tmpzr1t_l9r_go_relaxed.owl	mRNA-binding (hnRNP) protein-nucleus import|mRNA-binding (hnRNP) protein import into cell nucleus|mRNA-binding (hnRNP) protein transport from cytoplasm to nucleus					The reason for obsoletion is that all proteins are imported into the nucleus via the same mechanism, so the import of individual proteins should be captured with extensions or by GO-CAM models.	GO:0006606				True			biological_process											owl:Class	
GO:0052052	biolink:NamedThing	obsolete modification by symbiont of host morphology or physiology via protein secreted by type II secretion system	OBSOLETE. The process in which an organism effects a change in the structure or function of its host organism, mediated by a substance secreted by a type II secretion system in the organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it conflated the process in which a gene product is involved with the secretion system by which it reaches its target.					True			biological_process											owl:Class	
GO:0052235	biolink:NamedThing	obsolete negative aerotaxis in other organism involved in symbiotic interaction	OBSOLETE. The directed movement of a motile cell or organism towards a lower concentration of environmental oxygen within a second organism, where the two organisms are in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	negative aerotaxis in other organism during symbiotic interaction|negative aerotaxis within other organism during symbiotic interaction	https://github.com/geneontology/go-ontology/issues/18819				This term was obsoleted because it represents both a process and a location.					True			biological_process											owl:Class	
GO:0004242	biolink:NamedThing	obsolete beta-mitochondrial processing peptidase	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	beta-MPP|beta-mitochondrial processing peptidase					This term was made obsolete because it represents a gene product.	GO:0004222|GO:0005739				True			molecular_function											owl:Class	
GO:0052140	biolink:NamedThing	obsolete positive chemotaxis in host	OBSOLETE. The directed movement of a motile cell or organism towards a higher concentration of a specific chemical within its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	positive chemotaxis within host	https://github.com/geneontology/go-ontology/issues/18819				This term was obsoleted because it represents both a process and a location.					True			biological_process											owl:Class	
GO:0015832	biolink:NamedThing	obsolete holin	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	holin					This term was made obsolete because it represents a class of gene products.	GO:0019835				True			biological_process											owl:Class	
GO:0001167	biolink:NamedThing	obsolete RNA polymerase I transcription factor activity, sequence-specific DNA binding	OBSOLETE. Binding to a specific DNA sequence in order to modulate transcription by RNA polymerase I. The transcription factor may or may not also interact selectively with a protein or macromolecular complex.	tmpzr1t_l9r_go_relaxed.owl	sequence-specific DNA binding RNA polymerase I transcription factor activity	https://github.com/geneontology/go-ontology/issues/15787				This term was obsoleted because it represents two separate functions. The corresponding 'binding' term should be used in combination with a transcription regulator activity child.		krc	2011-02-03T04:07:46Z		True			molecular_function											owl:Class	
GO:0100034	biolink:NamedThing	obsolete regulation of 4,6-pyruvylated galactose residue biosynthetic process by transcription from RNA polymerase II promoter	OBSOLETE. Any transcription from RNA polymerase II promoter process that regulates 4,6-pyruvylated galactose residue biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it represents a GO-CAM model.		cjm	2015-04-02T04:13:19Z		True			biological_process											owl:Class	
GO:0007122	biolink:NamedThing	obsolete loss of asymmetric budding	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	loss of asymmetric budding					This term was made obsolete because it is a phenotype rather than a biological process.	GO:0006033				True			biological_process											owl:Class	
GO:0005566	biolink:NamedThing	obsolete ribosomal RNA	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	ribosomal RNA					This term was made obsolete because it represents a gene product.	GO:0005840|GO:0003735				True			molecular_function											owl:Class	
GO:0015335	biolink:NamedThing	obsolete heavy metal ion:hydrogen symporter activity	OBSOLETE. Catalysis of the reaction: Me2+(out) + H+(out) = Me2+(in) + H+(in), where Me2+ is Fe2+, Zn2+, Mn2+, Cu2+, Cd2+, Co2+, Ni2+ or Pb2+.	tmpzr1t_l9r_go_relaxed.owl	heavy metal ion:proton symporter activity|heavy metal ion:hydrogen symporter activity					This term was made obsolete because it represents a gene product and not a molecular function.	GO:0046873|GO:0015295				True			molecular_function											owl:Class	
GO:0033884	biolink:NamedThing	obsolete phosphoethanolamine/phosphocholine phosphatase activity	OBSOLETE. Catalysis of the reactions: O-phosphoethanolamine + H2O = ethanolamine + phosphate, and phosphocholine + H2O = choline + phosphate.	tmpzr1t_l9r_go_relaxed.owl	phosphoethanolamine phosphohydrolase activity|phosphoethanolamine/phosphocholine phosphatase activity|3X11A|PHOSPHO1					This term was made obsolete because it represents two reactions, and should be two separate terms.	GO:0052731|GO:0052732				True			molecular_function											owl:Class	
GO:0004216	biolink:NamedThing	obsolete cathepsin K activity	OBSOLETE. Catalysis of the hydrolysis of peptide bonds. Has a broad proteolytic activity. With small-molecule substrates and inhibitors, the major determinant of specificity is P2, which is preferably Leu, Met > Phe, and not Arg.	tmpzr1t_l9r_go_relaxed.owl	cathepsin O activity|cathepsin O2 activity|cathepsin X activity|cathepsin K activity			GO:0004197		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0060968	biolink:NamedThing	obsolete regulation of gene silencing	OBSOLETE. Any process that modulates the rate, frequency, or extent of gene silencing, the transcriptional or post-transcriptional process carried out at the cellular level that results in long-term gene inactivation.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/22202				This term was obsoleted because it was too broadly defined and could not be distinguished from 'GO:0040029 regulation of gene expression, epigenetic'.	GO:0040029	dph	2009-10-05T03:23:56Z		True			biological_process											owl:Class	
GO:0035423	biolink:NamedThing	obsolete inactivation of MAPK activity involved in innate immune response	OBSOLETE. Any process that terminates the activity of the active enzyme MAP kinase in the context of an innate immune response, a defense response mediated by germline encoded components that directly recognize components of potential pathogens.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/20242				This term was obsoleted because it represents a GO-CAM model.		bf	2010-03-29T01:28:59Z		True			biological_process											owl:Class	
GO:0001062	biolink:NamedThing	obsolete plastid PEP-A RNA polymerase activity	OBSOLETE. Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template that contains a plastid PEP-A RNA polymerase II specific promoter to direct initiation and catalyses DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/16738		GO:0003899		This term was obsoleted because the activity is the same as its parent.		krc	2010-10-19T03:38:49Z		True			molecular_function											owl:Class	
GO:0023047	biolink:NamedThing	obsolete signal initiation by chemical mediator	OBSOLETE. The process in which a chemical signal causes activation of a receptor.	tmpzr1t_l9r_go_relaxed.owl	signal initiation by chemical mediator					This term was made obsolete because the meaning of the term is ambiguous.	GO:0070887|GO:0038023|GO:0007165		2010-02-16T09:30:50Z		True			biological_process											owl:Class	
GO:0072321	biolink:NamedThing	obsolete chaperone-mediated protein transport	OBSOLETE. The directed movement of proteins into, out of or within a cell, or between cells, mediated by chaperone molecules that bind to the transported proteins.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/20850				This term was obsoleted because it represents a function within a process.	GO:0140597|GO:0015031	mah	2010-10-28T04:23:20Z		True			biological_process											owl:Class	
RO:0004009	biolink:NamedThing	has primary input		tmpzr1t_l9r_go_relaxed.owl					RO:0004009									external									has_primary_input			
GO:0019792	biolink:NamedThing	obsolete APG12 hydrolase activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	APG12 hydrolase activity					This term was made obsolete because it cannot be determined what its intended meaning was, because the term name is not found in the literature.	GO:0019783				True			molecular_function											owl:Class	
GO:0045884	biolink:NamedThing	obsolete regulation of survival gene product expression	OBSOLETE. Any process that modulates the frequency, rate or extent of survival gene product expression; survival gene products are those that antagonize the apoptotic program. Regulation can be at the transcriptional, translational, or posttranslational level.	tmpzr1t_l9r_go_relaxed.owl	regulation of survival gene product expression|regulation of survival gene products|regulation of survival gene product activity					This term was made obsolete because the meaning of the term is ambiguous: the same gene product may or may not have a role in apoptosis depending on the cell type, tissue type, condition, etc.					True			biological_process											owl:Class	
GO:0004323	biolink:NamedThing	obsolete multicopper ferroxidase iron transport mediator activity	OBSOLETE. Catalysis of the reaction: 4 Fe2+ + 4 H+ + O2 = 4 Fe3+ + 2 H2O.	tmpzr1t_l9r_go_relaxed.owl	multicopper ferroxidase iron transport mediator activity					This term was made obsolete because it represents a multifunctional gene product.	GO:0004322|GO:0005381				True			molecular_function											owl:Class	
GO:0046590	biolink:NamedThing	obsolete embryonic leg morphogenesis	OBSOLETE. The process, occurring in the embryo, by which the anatomical structures of the leg are generated and organized. A leg is a limb on which an animal walks and stands.	tmpzr1t_l9r_go_relaxed.owl	embryonic leg morphogenesis					This term was made obsolete because leg is a mechano-functional grouping, and having both 'leg morphogenesis' and 'hindlimb morphogenesis' terms causes errors in querying.	GO:0030326|GO:0035116				True			biological_process											owl:Class	
GO:0050523	biolink:NamedThing	obsolete oxidoreductase activity, acting on phosphorus or arsenic in donors, with other acceptors	OBSOLETE. Catalysis of an oxidation-reduction (redox) reaction in which phosphorus or arsenic acts as a hydrogen or electron donor and reduces an acceptor other than disulfide, NAD or NADP.	tmpzr1t_l9r_go_relaxed.owl	oxidoreductase activity, acting on phosphorus or arsenic in donors, with other acceptors					This term was made obsolete because it was an unnecessary grouping term.	GO:0030613				True			molecular_function											owl:Class	
GO:0016147	biolink:NamedThing	obsolete protein-synthesizing GTPase activity, elongation	OBSOLETE. Catalysis of the reaction: GTP + H2O = GDP + phosphate.	tmpzr1t_l9r_go_relaxed.owl	protein-synthesizing GTPase activity, elongation					This term was made obsolete because it contains both process and function information.	GO:0003746|GO:0003924|GO:0006412|GO:0006414				True			molecular_function											owl:Class	
GO:0048097	biolink:NamedThing	obsolete long-term maintenance of gene activation	OBSOLETE. Any mechanism, at the level of transcription or post-transcription, maintaining gene activation in the long-term.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/22015				This term has been obsoleted because its definition was not clear, and had no references and no annotations.	GO:0045815				True			biological_process											owl:Class	
GO:0045024	biolink:NamedThing	obsolete peptidyl-glutamyl peptide hydrolyzing enzyme activity	OBSOLETE. Catalysis of the cleavage of bonds after acidic amino acids and after branched chain amino acids.	tmpzr1t_l9r_go_relaxed.owl	peptidyl-glutamyl peptide hydrolyzing enzyme activity			GO:0008233		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:1990370	biolink:NamedThing	obsolete process resulting in tolerance to aldehyde	OBSOLETE. A response that results in a state of tolerance to aldehyde.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it does not represent a clear process.		tt	2014-04-23T22:30:50Z		True			biological_process											owl:Class	
GO:0016016	biolink:NamedThing	obsolete short-wave-sensitive opsin	OBSOLETE. An opsin with maximal absorption between 400 and 500 nm.	tmpzr1t_l9r_go_relaxed.owl	short-wave-sensitive opsin					This term was made obsolete because it refers to a class of proteins.	GO:0007603|GO:0016021|GO:0009881|GO:0016918|GO:0046876|GO:0009588				True			molecular_function											owl:Class	
GO:0009402	biolink:NamedThing	obsolete toxin resistance	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	toxin resistance			GO:0009636		This term was made obsolete because 'resistance' implies a phenotype rather than a biological process.					True			biological_process											owl:Class	
GO:0030825	biolink:NamedThing	obsolete positive regulation of cGMP metabolic process	OBSOLETE. Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving cGMP.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of cGMP metabolism|up regulation of cGMP metabolic process|up-regulation of cGMP metabolic process|stimulation of cGMP metabolic process|activation of cGMP metabolic process|upregulation of cGMP metabolic process					The reason for obsoletion is that this term represents the regulation of a signaling pathway, not regulation of metabolism.					True			biological_process											owl:Class	
GO:0039583	biolink:NamedThing	obsolete suppression by virus of host PKR activity by positive regulation of PKR catabolic process	OBSOLETE. Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host PKR (protein kinase regulated by RNA) activity by promoting the degradation of PKR via the proteosome. For example, the Rift Valley fever virus (RVFV) NSs protein induces the down-regulation of PKR by degradation through proteasomes.	tmpzr1t_l9r_go_relaxed.owl	promotion by virus of proteosome-dependent PKR degradation|downregulation of PKR by degradation through proteosome					The reason for obsoleting this term is that it is too specific. The exact molecular roles of the individual proteins should be captured separately.		bf	2012-05-02T02:49:30Z		True			biological_process											owl:Class	
GO:0001191	biolink:NamedThing	obsolete transcriptional repressor activity, RNA polymerase II transcription factor binding	OBSOLETE. Binding to an RNA polymerase II transcription factor, which may be a single protein or a complex, in order to stop, prevent, or reduce the frequency, rate or extent of transcription from an RNA polymerase II promoter. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well.	tmpzr1t_l9r_go_relaxed.owl	RNA polymerase II transcription repressor activity|RNA polymerase II transcription factor binding transcription repressor activity|RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription	https://github.com/geneontology/go-ontology/issues/16053				The reason for obsoletion is that this concept is partly covered by other concepts in the ontology and usage has been inconsistent.	GO:0001227|GO:0061629	krc	2011-08-25T02:12:30Z		True			molecular_function											owl:Class	
GO:0004226	biolink:NamedThing	obsolete Gly-X carboxypeptidase activity	OBSOLETE. Catalysis of the reaction: peptidyl-Gly-Xaa + H2O = peptidyl-Gly + Xaa.	tmpzr1t_l9r_go_relaxed.owl	Gly-Xaa carboxypeptidase activity|carboxypeptidase a|glycine carboxypeptidase activity|peptidase alpha|yeast carboxypeptidase activity|Gly-X carboxypeptidase activity|carboxypeptidase S activity			GO:0004181		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0005698	biolink:NamedThing	obsolete centromere	OBSOLETE. The region of a eukaryotic chromosome that is attached to the spindle during nuclear division. It is defined genetically as the region of the chromosome that always segregates at the first division of meiosis; the region of the chromosome in which no crossing over occurs. At the start of M phase, each chromosome consists of two sister chromatids with a constriction at a point which forms the centromere. During late prophase two kinetochores assemble on each centromere, one kinetochore on each sister chromatid.	tmpzr1t_l9r_go_relaxed.owl	centromere					This term was made obsolete because it is a genetically defined region and not a specific subcellular localization.	GO:0000775				True			cellular_component											owl:Class	
GO:0008605	biolink:NamedThing	obsolete protein kinase CK2 regulator activity	OBSOLETE. Modulation of the activity of the enzyme protein kinase CK2.	tmpzr1t_l9r_go_relaxed.owl	protein kinase CK2 regulator activity|protein kinase CK2, intrinsic regulator activity|casein kinase II, regulator			GO:0019887		This term was made obsolete because it represents a regulator of an obsolete molecular function.					True			molecular_function											owl:Class	
GO:0001629	biolink:NamedThing	obsolete G-protein receptor 45-like receptor activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	GPR45-like receptor|G protein receptor 45-like receptor activity|G-protein receptor 45-like receptor activity					This term was made obsolete because it represents a gene product, was not defined, and is named based on protein features.					True			molecular_function											owl:Class	
GO:0015059	biolink:NamedThing	obsolete blue-sensitive opsin	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	blue-sensitive opsin					This term was made obsolete because it refers to a class of proteins.	GO:0007603|GO:0016021|GO:0009881|GO:0016918|GO:0046876|GO:0009588				True			molecular_function											owl:Class	
GO:0045890	biolink:NamedThing	obsolete regulation of transcription of homeotic gene (trithorax group)	OBSOLETE. Any process that modulates the frequency, rate or extent of transcription of homeotic genes of the trithorax group.	tmpzr1t_l9r_go_relaxed.owl	regulation of transcription of homeotic gene (trithorax group)					This term was made obsolete because it relates to a specific gene family rather than a process.	GO:0006357				True			biological_process											owl:Class	
GO:1901244	biolink:NamedThing	obsolete positive regulation of transcription from RNA polymerase II promoter involved in defense response to fungus	OBSOLETE. Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter to protect the cell or organism in response to the presence of a fungus.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of gene-specific transcription from RNA polymerase II promoter involved in defense response to fungus|stimulation of transcription from RNA polymerase II promoter involved in defence response to fungi|up-regulation of transcription from RNA polymerase II promoter involved in defense response to fungus|up regulation of global transcription from RNA polymerase II promoter involved in defense response to fungi|upregulation of global transcription from RNA polymerase II promoter involved in defence response to fungus|up-regulation of global transcription from RNA polymerase II promoter involved in defense response to fungus|upregulation of transcription from RNA polymerase II promoter involved in defense response to fungus|stimulation of global transcription from RNA polymerase II promoter involved in defense response to fungi|up-regulation of global transcription from RNA polymerase II promoter involved in defence response to fungi|positive regulation of gene-specific transcription from RNA polymerase II promoter involved in defense response to fungi|up regulation of global transcription from RNA polymerase II promoter involved in defense response to fungus|up-regulation of global transcription from RNA polymerase II promoter involved in defence response to fungus|positive regulation of transcription from RNA polymerase II promoter involved in defense response to fungi|positive regulation of global transcription from Pol II promoter involved in defence response to fungi|stimulation of transcription from RNA polymerase II promoter involved in defense response to fungi|positive regulation of global transcription from Pol II promoter involved in defence response to fungus|stimulation of global transcription from RNA polymerase II promoter involved in defence response to fungi|up-regulation of global transcription from RNA polymerase II promoter involved in defense response to fungi|activation of global transcription from RNA polymerase II promoter involved in defence response to fungus|up regulation of transcription from RNA polymerase II promoter involved in defence response to fungus|positive regulation of transcription from Pol II promoter involved in defense response to fungus|up-regulation of transcription from RNA polymerase II promoter involved in defence response to fungus|stimulation of transcription from RNA polymerase II promoter involved in defence response to fungus|stimulation of global transcription from RNA polymerase II promoter involved in defense response to fungus|up-regulation of transcription from RNA polymerase II promoter involved in defence response to fungi|positive regulation of transcription from RNA polymerase II promoter involved in defence response to fungus|positive regulation of transcription from Pol II promoter involved in defence response to fungus|upregulation of transcription from RNA polymerase II promoter involved in defence response to fungi|activation of global transcription from RNA polymerase II promoter involved in defence response to fungi|positive regulation of transcription from Pol II promoter involved in defense response to fungi|positive regulation of transcription from RNA polymerase II promoter involved in defence response to fungi|up regulation of transcription from RNA polymerase II promoter involved in defence response to fungi|up regulation of global transcription from RNA polymerase II promoter involved in defence response to fungi|activation of global transcription from RNA polymerase II promoter involved in defense response to fungi|up-regulation of transcription from RNA polymerase II promoter involved in defense response to fungi|activation of transcription from RNA polymerase II promoter involved in defence response to fungus|upregulation of global transcription from RNA polymerase II promoter involved in defense response to fungus|positive regulation of gene-specific transcription from RNA polymerase II promoter involved in defence response to fungus|positive regulation of transcription from Pol II promoter involved in defence response to fungi|upregulation of global transcription from RNA polymerase II promoter involved in defence response to fungi|stimulation of global transcription from RNA polymerase II promoter involved in defence response to fungus|activation of transcription from RNA polymerase II promoter involved in defense response to fungi|up regulation of transcription from RNA polymerase II promoter involved in defense response to fungus|positive regulation of global transcription from Pol II promoter involved in defense response to fungus|activation of global transcription from RNA polymerase II promoter involved in defense response to fungus|upregulation of transcription from RNA polymerase II promoter involved in defense response to fungi|stimulation of transcription from RNA polymerase II promoter involved in defense response to fungus|positive regulation of gene-specific transcription from RNA polymerase II promoter involved in defence response to fungi|positive regulation of global transcription from Pol II promoter involved in defense response to fungi|upregulation of transcription from RNA polymerase II promoter involved in defence response to fungus|activation of transcription from RNA polymerase II promoter involved in defence response to fungi|up regulation of transcription from RNA polymerase II promoter involved in defense response to fungi|upregulation of global transcription from RNA polymerase II promoter involved in defense response to fungi|up regulation of global transcription from RNA polymerase II promoter involved in defence response to fungus|activation of transcription from RNA polymerase II promoter involved in defense response to fungus					This term was obsoleted because it represents a GO-CAM model.	GO:0050832|GO:0045944	kmv	2012-08-07T18:40:02Z		True			biological_process											owl:Class	
GO:0009049	biolink:NamedThing	obsolete aspartic-type signal peptidase activity	OBSOLETE. Catalysis of the cleavage of a signal peptide from a protein precursor by an aspartic endopeptidase mechanism.	tmpzr1t_l9r_go_relaxed.owl	aspartic-type signal peptidase activity			GO:0004190		This term was made obsolete because 'signal peptide' is difficult to define unambiguously, and because the term refers to gene products.					True			molecular_function											owl:Class	
GO:0044215	biolink:NamedThing	obsolete other organism	OBSOLETE. A secondary organism with which the first organism is interacting.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it represents an organism, which is outside the scope of GO.		jl	2009-11-12T01:04:58Z		True			cellular_component											owl:Class	
GO:0030940	biolink:NamedThing	obsolete response to short-day photoperiod	OBSOLETE. A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a photoperiod, an intermittent cycle of light (day) and dark (night) photoperiod regimes, with the dark phase being longer than the light.	tmpzr1t_l9r_go_relaxed.owl	response to short-day photoperiod					This term was made obsolete because it was wrongly defined.	GO:0048572				True			biological_process											owl:Class	
GO:0000988	biolink:NamedThing	obsolete transcription factor activity, protein binding	OBSOLETE. Binding to a protein or protein complex, to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well.	tmpzr1t_l9r_go_relaxed.owl	protein binding transcription factor activity|transcription factor activity	https://github.com/geneontology/go-ontology/issues/16053				The reason for obsoletion is that this concept is partly covered by other concepts in the ontology and usage has been inconsistent.	GO:0140110|GO:0005515	krc	2010-08-10T04:03:22Z		True			molecular_function											owl:Class	
GO:0023044	biolink:NamedThing	obsolete signaling via chemical mediator	OBSOLETE. The process in which information is sent from one location to another, within a living organism or between living organisms, via a chemical mediator.	tmpzr1t_l9r_go_relaxed.owl	signaling via chemical mediator|signalling via chemical mediator					This term was made obsolete because the meaning of the term is ambiguous.	GO:0023052		2010-02-16T09:30:50Z		True			biological_process											owl:Class	
GO:0003805	biolink:NamedThing	obsolete coagulation factor XIa activity	OBSOLETE. Catalysis of the selective cleavage of Arg-Ala and Arg-Val bonds in factor IX to form factor IXa.	tmpzr1t_l9r_go_relaxed.owl	activated blood-coagulation factor XI|activated plasma thromboplastin antecedent|blood coagulation factor XI activity|coagulation factor XIa activity|blood-coagulation factor XIa|plasma thromboplastin antecedent activity			GO:0004252		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:1990978	biolink:NamedThing	obsolete response to viscosity	OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a viscosity stimulus.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted at the TermGenie Gatekeeper stage.		sl	2016-08-17T20:10:36Z		True			biological_process											owl:Class	
GO:0019016	biolink:NamedThing	obsolete non-segmented viral genome	OBSOLETE. A viral genome that consists of one continuous nucleic acid molecule.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it does not represent a GO cellular component.					True			cellular_component											owl:Class	
GO:0031933	biolink:NamedThing	obsolete telomeric heterochromatin	OBSOLETE. Heterochromatic regions of the chromosome found at the telomeres.	tmpzr1t_l9r_go_relaxed.owl	telomeric chromatin	https://github.com/geneontology/go-ontology/issues/19086				This term was obsoleted because there is no heterochromatin at the telomere and the term had been used inconsistently.					True			cellular_component											owl:Class	
GO:1905253	biolink:NamedThing	obsolete negative regulation of epidermal growth factor receptor signaling pathway involved in heart process	OBSOLETE. Any negative regulation of epidermal growth factor receptor signaling pathway that is involved in heart process.	tmpzr1t_l9r_go_relaxed.owl	downregulation of epidermal growth factor receptor signaling pathway involved in cardiac process|negative regulation of EGFR signaling pathway involved in cardiac process|negative regulation of EGF receptor signaling pathway involved in heart process|down regulation of epidermal growth factor receptor signaling pathway involved in heart process|negative regulation of epidermal growth factor receptor signaling pathway involved in cardiac process|down-regulation of epidermal growth factor receptor signaling pathway involved in cardiac process|negative regulation of EGFR signaling pathway involved in heart process|negative regulation of EGF receptor signalling pathway involved in heart process|inhibition of epidermal growth factor receptor signaling pathway involved in cardiac process|down-regulation of epidermal growth factor receptor signaling pathway involved in heart process|down regulation of epidermal growth factor receptor signaling pathway involved in cardiac process|inhibition of epidermal growth factor receptor signaling pathway involved in heart process|downregulation of epidermal growth factor receptor signaling pathway involved in heart process|negative regulation of EGF receptor signalling pathway involved in cardiac process|negative regulation of EGF receptor signaling pathway involved in cardiac process					This term was obsoleted at the TermGenie Gatekeeper stage.		bc	2016-06-10T09:21:10Z		True			biological_process											owl:Class	
GO:1990093	biolink:NamedThing	obsolete negative regulation of N-methyl-D-aspartate receptor clustering	OBSOLETE. The negative regulation of the receptor clustering process in which N-methyl-D-aspartate (NMDA) receptors are localized to distinct domains in the cell membrane.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of NMDA receptor clustering|negative regulation of N-methyl-D-aspartate receptor clustering					This term was obsoleted at the TermGenie Gatekeeper stage.		sl	2013-05-06T17:39:44Z		True			biological_process											owl:Class	
GO:0005187	biolink:NamedThing	obsolete storage protein	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	storage protein			GO:0045735		This term was made obsolete because it describes a cellular location rather than a function.					True			molecular_function											owl:Class	
GO:0004210	biolink:NamedThing	obsolete caspase-7 activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	caspase-7 activity			GO:0004197		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0008044	biolink:NamedThing	obsolete adult behavior (sensu Insecta)	OBSOLETE. Behavior in a fully developed and mature organism, as seen in insects.	tmpzr1t_l9r_go_relaxed.owl	adult behavior (sensu Insecta)			GO:0030534		This term was made obsolete because there is no clear difference between the sensu Insecta term and the generic term.					True			biological_process											owl:Class	
GO:0046266	biolink:NamedThing	obsolete triethanolamine biosynthetic process	OBSOLETE. The chemical reactions and pathways resulting in the formation of triethanolamine, a combustible, hygroscopic, colorless liquid commonly used in dry-cleaning solutions, cosmetics, detergents, textile processing, wool scouring, and as a corrosion inhibitor and pharmaceutical alkalizing agent.	tmpzr1t_l9r_go_relaxed.owl	triethanolamine anabolism|triethanolamine biosynthetic process|triethanolamine biosynthesis|triethanolamine synthesis|triethanolamine formation			GO:0018981		This term was made obsolete because triethanolamine is not synthesized by living organisms, and GO does not cover non-biological processes.					True			biological_process											owl:Class	
GO:0000208	biolink:NamedThing	obsolete MAPK import into nucleus involved in osmosensory signaling pathway	OBSOLETE. The directed movement of a MAP kinase to the nucleus during osmolarity sensing.	tmpzr1t_l9r_go_relaxed.owl	MAPK import into nucleus involved in osmosensory signalling pathway|nuclear translocation of MAPK during osmolarity sensing|MAPK import into nucleus during osmolarity sensing|nuclear translocation of MAPK involved in osmosensory signalling pathway|osmolarity sensing, MAPK import into nucleus|nuclear translocation of MAPK involved in osmosensory signaling pathway|osmolarity sensing, nuclear translocation of MAPK					The reason for obsoletion is that this term represents a GO-CAM model.	GO:0006606				True			biological_process											owl:Class	
GO:0044239	biolink:NamedThing	obsolete salivary polysaccharide catabolic process	OBSOLETE. The chemical reactions and pathways resulting in the breakdown of polysaccharides by salivary amylase. Salivary amylase is released by salivary glands, usually in the mouth.	tmpzr1t_l9r_go_relaxed.owl	salivary polysaccharide breakdown|salivary polysaccharide catabolism|salivary polysaccharide degradation					The reason for obsoletion is that this term represents the location of a process, which should be captured by the relation 'occurs in'.	GO:0000272				True			biological_process											owl:Class	
GO:1905159	biolink:NamedThing	obsolete negative regulation of Factor XII activation	OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of Factor XII activation.	tmpzr1t_l9r_go_relaxed.owl	inhibition of Hageman factor activation|downregulation of Hageman factor activation|inhibition of Factor XII activation|down regulation of Factor XII activation|downregulation of Factor XII activation|down-regulation of Factor XII activation|negative regulation of Hageman factor activation|down-regulation of Hageman factor activation|down regulation of Hageman factor activation					This term was accidentally approved after TermGenie review.  It should not have been approved.		sl	2016-04-19T23:03:34Z		True			biological_process											owl:Class	
GO:0009076	biolink:NamedThing	obsolete histidine family amino acid biosynthetic process	OBSOLETE. The chemical reactions and pathways resulting in the formation of amino acids of the histidine family.	tmpzr1t_l9r_go_relaxed.owl	histidine family amino acid biosynthetic process|histidine family amino acid anabolism|histidine family amino acid formation|histidine family amino acid synthesis|histidine family amino acid biosynthesis			GO:0000105		This term was made obsolete because it was an unnecessary grouping term, as histidine would be the only member of this family.					True			biological_process											owl:Class	
GO:1904722	biolink:NamedThing	obsolete positive regulation of mRNA endonucleolytic cleavage involved in unfolded protein response	OBSOLETE. Any process that activates or increases the frequency, rate or extent of mRNA endonucleolytic cleavage involved in unfolded protein response.	tmpzr1t_l9r_go_relaxed.owl	activation of mRNA endonucleolytic cleavage involved in unfolded protein response|up regulation of HAC1-type intron splice site recognition and cleavage|positive regulation of HAC1 mRNA cleavage|upregulation of XBP1 mRNA cleavage|up regulation of XBP1 mRNA cleavage|activation of IRE1-mediated XBP-1 mRNA cleavage|up regulation of HAC1 mRNA cleavage|positive regulation of XBP1 mRNA cleavage|up-regulation of XBP1 mRNA cleavage|upregulation of HAC1-type intron splice site recognition and cleavage|upregulation of mRNA endonucleolytic cleavage involved in unfolded protein response|up-regulation of HAC1-type intron splice site recognition and cleavage|upregulation of HAC1 mRNA cleavage|activation of HAC1-type intron splice site recognition and cleavage|up-regulation of IRE1-mediated XBP-1 mRNA cleavage|positive regulation of HAC1-type intron splice site recognition and cleavage|up-regulation of HAC1 mRNA cleavage|up-regulation of mRNA endonucleolytic cleavage involved in unfolded protein response|positive regulation of IRE1-mediated XBP-1 mRNA cleavage|up regulation of mRNA endonucleolytic cleavage involved in unfolded protein response|upregulation of IRE1-mediated XBP-1 mRNA cleavage|activation of HAC1 mRNA cleavage|up regulation of IRE1-mediated XBP-1 mRNA cleavage|activation of XBP1 mRNA cleavage					The reason for obsoletion is that this process being regulated (GO:0070055 mRNA endonucleolytic cleavage involved in unfolded protein response) was obsoleted.	GO:1903896	bf	2015-10-08T14:53:02Z		True			biological_process											owl:Class	
OIO:creation_date	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl																									owl:AnnotationProperty	
GO:1902579	biolink:NamedThing	obsolete multi-organism localization	OBSOLETE. A localization which involves another organism.	tmpzr1t_l9r_go_relaxed.owl	multi organism localization	https://github.com/geneontology/go-ontology/issues/21459				This term was obsoleted because there is no evidence that this process exists.		jl	2013-12-18T13:51:13Z		True			biological_process											owl:Class	
GO:0100033	biolink:NamedThing	obsolete regulation of fungal-type cell wall biogenesis by transcription from RNA polymerase II promoter	OBSOLETE. Any transcription from RNA polymerase II promoter process that regulates fungal-type cell wall biogenesis.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it represents a GO-CAM model.		cjm	2015-04-02T04:13:19Z		True			biological_process											owl:Class	
GO:0045825	biolink:NamedThing	obsolete negative regulation of intermediate filament polymerization and/or depolymerization	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of intermediate filament polymerization and/or depolymerization.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of intermediate filament polymerization and/or depolymerization					This term was made obsolete because it has been split.	GO:0030840|GO:0030843				True			biological_process											owl:Class	
GO:0004437	biolink:NamedThing	obsolete inositol or phosphatidylinositol phosphatase activity	OBSOLETE. Catalysis of the removal of a phosphate group from phosphorylated myo-inositol (1,2,3,5/4,6-cyclohexanehexol) or a phosphatidylinositol.	tmpzr1t_l9r_go_relaxed.owl	inositol or phosphatidylinositol phosphatase activity|inositol/phosphatidylinositol phosphatase activity					This term was made obsolete because it is a grouping term representing two quite different sets of entities, hexose sugars and glycerophospholipids.	GO:0034594|GO:0052744|GO:0052745|GO:0034593				True			molecular_function											owl:Class	
GO:1903821	biolink:NamedThing	obsolete detection of stimulus involved in morphogenesis checkpoint	OBSOLETE. Any detection of stimulus that is involved in morphogenesis checkpoint.	tmpzr1t_l9r_go_relaxed.owl	perception of stimulus involved in septin checkpoint|stimulus sensing involved in septin checkpoint|detection of stimulus involved in septin checkpoint|stimulus detection involved in morphogenesis checkpoint|perception of stimulus involved in morphogenesis checkpoint|stimulus detection involved in septin checkpoint|stimulus sensing involved in morphogenesis checkpoint	https://github.com/geneontology/go-ontology/issues/20976				This term was obsoleted because it corresponds to a molecular function.		jl	2015-01-19T15:03:59Z		True			biological_process											owl:Class	
GO:1990754	biolink:NamedThing	obsolete GABAergic neuronal action potential	OBSOLETE. An action potential that occurs in a GABAergic neuron.	tmpzr1t_l9r_go_relaxed.owl	GABAergic neuronal action potential					This term was obsoleted at the TermGenie Gatekeeper stage.		pg	2015-05-28T08:58:42Z		True			biological_process											owl:Class	
GO:0075099	biolink:NamedThing	obsolete modulation by host of symbiont protein kinase-mediated signal transduction	OBSOLETE. Any process in which the host organism modulates the frequency, rate or extent of protein kinase-mediated signal transduction in the symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl						The reason for obsoletion is that there is no evidence that the host can modulate or regulate a symbiont's signal transduction pathway.					True			biological_process											owl:Class	
GO:0004289	biolink:NamedThing	obsolete subtilase activity	OBSOLETE. Was not defined before being made obsolete.	tmpzr1t_l9r_go_relaxed.owl	subtilase activity			GO:0004252		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0015002	biolink:NamedThing	obsolete heme-copper terminal oxidase activity	OBSOLETE. Catalysis of the four-electron reduction of dioxygen (O2) to water, coupled to generation of a proton electrochemical gradient across a membrane.	tmpzr1t_l9r_go_relaxed.owl	haem-copper terminal oxidase activity	https://github.com/geneontology/go-ontology/issues/20924				This term was obsoleted because it groups the last enzymes in the electron transport chain, and is not an appropriate grouping term for molecular function.					True			molecular_function											owl:Class	
GO:0044698	biolink:NamedThing	obsolete morphogenesis of symbiont in host cell	OBSOLETE. The process in which a symbiont undergoes a change in shape or form, within the host's cell.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/20305				This term was obsoleted because it represents both a process and a location.		jl	2012-09-19T14:10:53Z		True			biological_process											owl:Class	
GO:0005647	biolink:NamedThing	obsolete importin, alpha-subunit	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	karyopherin-alpha|importin, alpha-subunit					This term was made obsolete because it represents a single gene product and not a complex.	GO:0005643|GO:0005737|GO:0017056|GO:0005634				True			cellular_component											owl:Class	
GO:1905254	biolink:NamedThing	obsolete positive regulation of epidermal growth factor receptor signaling pathway involved in heart process	OBSOLETE. Any positive regulation of epidermal growth factor receptor signaling pathway that is involved in heart process.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of EGFR signaling pathway involved in cardiac process|positive regulation of EGF receptor signaling pathway involved in heart process|positive regulation of EGF receptor signaling pathway involved in cardiac process|stimulation of epidermal growth factor receptor signaling pathway involved in heart process|positive regulation of EGF receptor signalling pathway involved in cardiac process|activation of epidermal growth factor receptor signaling pathway involved in cardiac process|up-regulation of epidermal growth factor receptor signaling pathway involved in cardiac process|upregulation of epidermal growth factor receptor signaling pathway involved in cardiac process|up-regulation of epidermal growth factor receptor signaling pathway involved in heart process|up regulation of epidermal growth factor receptor signaling pathway involved in cardiac process|positive regulation of epidermal growth factor receptor signaling pathway involved in cardiac process|activation of epidermal growth factor receptor signaling pathway involved in heart process|upregulation of epidermal growth factor receptor signaling pathway involved in heart process|stimulation of epidermal growth factor receptor signaling pathway involved in cardiac process|positive regulation of EGF receptor signalling pathway involved in heart process|positive regulation of EGFR signaling pathway involved in heart process|up regulation of epidermal growth factor receptor signaling pathway involved in heart process					This term was obsoleted at the TermGenie Gatekeeper stage.		bc	2016-06-10T09:21:18Z		True			biological_process											owl:Class	
GO:0023006	biolink:NamedThing	obsolete signal initiation by amino acid	OBSOLETE. The process in which an amino acid signal causes activation of a receptor.	tmpzr1t_l9r_go_relaxed.owl	signal initiation by amino acid					This term was made obsolete because the meaning of the term is ambiguous.	GO:0008066|GO:0071230|GO:0007215		2010-02-16T09:30:50Z		True			biological_process											owl:Class	
GO:0015525	biolink:NamedThing	obsolete carbonyl cyanide m-chlorophenylhydrazone/nalidixic acid/organomercurials:hydrogen antiporter activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	carbonyl cyanide m-chlorophenylhydrazone/nalidixic acid/organomercurials:proton antiporter activity|carbonyl cyanide m-chlorophenylhydrazone/nalidixic acid/organomercurials:hydrogen antiporter activity					This term was made obsolete because it represents a multifunctional gene product.	GO:0015549|GO:0015547|GO:0015548				True			molecular_function											owl:Class	
GO:0016665	biolink:NamedThing	obsolete oxidoreductase activity, acting on other nitrogenous compounds as donors, other acceptors	OBSOLETE. Catalysis of an oxidation-reduction (redox) reaction in which a nitrogenous group, excluding NH and NH2 groups, acts as a hydrogen or electron donor and reduces an acceptor other than a cytochrome, an iron-sulfur protein, oxygen, NAD or NADP.	tmpzr1t_l9r_go_relaxed.owl	oxidoreductase activity, acting on other nitrogenous compounds as donors, other acceptors					This term was made obsolete because it was an unnecessary grouping term.	GO:0016661				True			molecular_function											owl:Class	
GO:0047193	biolink:NamedThing	obsolete CDP-acylglycerol O-arachidonoyltransferase activity	OBSOLETE. Catalysis of the reaction: CDP-acylglycerol + arachidonyl-CoA = CDP-diacylglycerol + CoA.	tmpzr1t_l9r_go_relaxed.owl	CDP-acylglycerol O-arachidonyltransferase activity|arachidonyl-CoA:CDP-acylglycerol O-arachidonyltransferase activity|CDP-acylglycerol O-arachidonoyltransferase activity|CDPacylglycerol O-arachidonyltransferase activity|arachidonoyl-CoA:CDP-acylglycerol O-arachidonoyltransferase activity				MetaCyc:2.3.1.70-RXN	This term was made obsolete because the evidence for the existence of this reaction was retracted. Please see PMID:6885763 for more information.					True			molecular_function											owl:Class	
GO:0018338	biolink:NamedThing	obsolete protein amino acid cinnamylation	OBSOLETE. The modification of a protein amino acid by cinnamylation.	tmpzr1t_l9r_go_relaxed.owl	protein amino acid cinnamylation					This term was made obsolete because it was an unnecessary grouping term.	GO:0018097				True			biological_process											owl:Class	
GO:0100040	biolink:NamedThing	obsolete negative regulation of invasive growth in response to glucose limitation by transcription from RNA polymerase II promoter	OBSOLETE. Any transcription from RNA polymerase II promoter process that negatively regulates invasive growth in response to glucose limitation.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it represents a GO-CAM model.		cjm	2015-04-02T04:13:19Z		True			biological_process											owl:Class	
GO:0030657	biolink:NamedThing	obsolete regulation of coenzyme and prosthetic group metabolic process	OBSOLETE. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving coenzymes and prosthetic groups.	tmpzr1t_l9r_go_relaxed.owl	regulation of coenzyme and prosthetic group metabolic process					This term was made obsolete because it was replaced by more specific terms.	GO:0051199				True			biological_process											owl:Class	
GO:0007575	biolink:NamedThing	obsolete nucleolar size increase	OBSOLETE. The process of nucleolar expansion.	tmpzr1t_l9r_go_relaxed.owl	nucleolar size increase					This term was made obsolete because it does not describe a biological process.	GO:0007576|GO:0007571				True			biological_process											owl:Class	
GO:0075200	biolink:NamedThing	obsolete negative regulation of symbiont haustorium neck formation for entry into host	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of symbiont haustorium neck formation for entry into host. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/18779				This term was obsoleted because there is no evidence that this process exists.					True			biological_process											owl:Class	
GO:1990368	biolink:NamedThing	obsolete process resulting in tolerance to hydrolysate	OBSOLETE. A response that results in a state of tolerance to hydrolysate (product of hydrolysis).	tmpzr1t_l9r_go_relaxed.owl	process resulting in tolerance to hydrolysate					This term was obsoleted at the TermGenie Gatekeeper stage.		tt	2014-04-23T22:27:51Z		True			biological_process											owl:Class	
GO:0004219	biolink:NamedThing	obsolete pyroglutamyl-peptidase I activity	OBSOLETE. Catalysis of the reaction: pyroglutamyl-peptide + H2O = pyroglutamate + peptide.	tmpzr1t_l9r_go_relaxed.owl	pyrrolidonecarboxylyl peptidase activity|pyroglutamyl aminopeptidase activity|L-pyroglutamyl peptide hydrolase activity|pyrrolidone-carboxyl peptidase activity|pyroglutamyl-peptidase I activity|5-oxoprolyl-peptidase activity|pyrrolidone carboxyl peptidase activity|pyroglutamidase activity|L-pyrrolidonecarboxylate peptidase activity|pyrrolidonyl peptidase activity|pyroglutamate aminopeptidase activity|PYRase activity|pyrrolidone-carboxylate peptidase activity				EC:3.4.19.3|MetaCyc:PYROGLUTAMYL-PEPTIDASE-I-RXN	This term was made obsolete because it represents a gene product.	GO:0016920|GO:0008234				True			molecular_function											owl:Class	
GO:0097033	biolink:NamedThing	obsolete mitochondrial respiratory chain complex III biogenesis	OBSOLETE. The biogenesis of a mitochondrial respiratory chain complex III (also known as cytochrome bc(1) complex or ubiquinol-cytochrome c reductase), a protein complex located in the mitochondrial inner membrane that forms part of the mitochondrial respiratory chain. Includes the synthesis of constituent proteins and their aggregation, arrangement and bonding together.	tmpzr1t_l9r_go_relaxed.owl	mitochondrial cytochrome bc(1) complex biogenesis	https://github.com/geneontology/go-ontology/issues/15173				The reason for obsoletion is that 'biogenesis' as related to a protein is translation, and there is no indication that the members of these complexes are synthesized in a particular way. Historically biogenesis terms were created for some processes when the level of a molecule was changed by an unknown mechanism, for instance transcription, translation, assembly etc. This is now considered too indirect for annotation.		pr	2011-04-05T03:00:31Z		True			biological_process											owl:Class	
GO:0001723	biolink:NamedThing	obsolete type II intermediate filament associated protein	OBSOLETE. High molecular weight (100-300 kDa) proteins that associate with intermediate filaments to cross-link them into loose networks.	tmpzr1t_l9r_go_relaxed.owl	type II intermediate filament associated protein			GO:0005882		This term was made obsolete because it represents a single gene product and not a complex.					True			cellular_component											owl:Class	
GO:0052507	biolink:NamedThing	obsolete positive regulation by organism of defense-related symbiont jasmonic acid-mediated signal transduction pathway	OBSOLETE. Any process by which an organism activates, maintains or increases the frequency, rate or extent of symbiont jasmonic acid-mediated signal transduction pathways during the symbiont defense response. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	positive regulation by organism of defense-related symbiont jasmonic acid-mediated signal transduction pathway|activation by organism of defense-related symbiont jasmonic acid-mediated signal transduction pathway|activation by organism of defense-related symbiont SA-mediated signal transduction pathway|induction by organism of defense-related symbiont SA-mediated signal transduction pathway|upregulation by organism of defense-related symbiont SA-mediated signal transduction pathway|upregulation by organism of defense-related symbiont jasmonic acid-mediated signal transduction pathway|induction by organism of defense-related symbiont jasmonic acid-mediated signal transduction pathway|positive regulation by organism of defense-related symbiont SA-mediated signal transduction pathway					This term was made obsolete because it does not represent a real biological process.					True			biological_process											owl:Class	
GO:0005276	biolink:NamedThing	obsolete vesicular amino acid:proton antiporter activity	OBSOLETE. Enables the transfer of a solute or solutes from one side of a vesicle membrane to the other according to the reaction: H+(in) + amino acid(out) = H+(out) + amino acid(in).	tmpzr1t_l9r_go_relaxed.owl	vesicular hydrogen:amino acid antiporter activity|hydrogen:vesicular amine antiporter activity					The reason for obsoletion is that the cellular component does not belong is the MF according to the documentation: http://wiki.geneontology.org/index.php/Transporter_terms_standard_definitions					True			molecular_function											owl:Class	
GO:0005651	biolink:NamedThing	obsolete exportin	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	exportin					This term was made obsolete because it represents a single gene product and not a complex.	GO:0005737|GO:0017056|GO:0005634|GO:0005643				True			cellular_component											owl:Class	
GO:0042992	biolink:NamedThing	obsolete negative regulation of transcription factor import into nucleus	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the movement of a transcription factor from the cytoplasm to the nucleus.	tmpzr1t_l9r_go_relaxed.owl	inhibition of transcription factor import into nucleus|down regulation of transcription factor import into nucleus|down-regulation of transcription factor import into nucleus|negative regulation of transcription factor import into cell nucleus|downregulation of transcription factor import into nucleus|negative regulation of transcription factor transport from cytoplasm to nucleus|negative regulation of transcription factor-nucleus import					The reason for obsoletion is that there is no distinct pathway to import transcription factors into the nucleus.	GO:0042308				True			biological_process											owl:Class	
GO:0090202	biolink:NamedThing	obsolete gene looping	OBSOLETE. The formation and maintenance of DNA loops that juxtapose sequentially separated regions of RNA polymerase II-transcribed genes.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/20204				This term was obsoleted because it was defined like a molecular function.	GO:0140587	tb	2009-12-18T11:56:00Z		True			biological_process											owl:Class	
GO:0098503	biolink:NamedThing	obsolete DNA 3' dephosphorylation	OBSOLETE. The process of removing a 3' phosphate group from a DNA molecule.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it represents a molecular function, and not a specific coordinated process.		dos	2013-09-18T14:51:17Z		True			biological_process											owl:Class	
GO:0070827	biolink:NamedThing	obsolete chromatin maintenance	OBSOLETE. The chromatin organization process that preserves chromatin in a stable functional or structural state.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/22013				This term was obsoleted because it is redundant with chromatin organization and assembly terms.		mah	2009-07-23T04:09:59Z		True			biological_process											owl:Class	
GO:0052508	biolink:NamedThing	obsolete positive regulation by organism of defense-related symbiont salicylic acid-mediated signal transduction pathway	OBSOLETE. Any process by which an organism activates, maintains or increases the frequency, rate or extent of symbiont salicylic acid-mediated signal transduction pathways during the symbiont defense response. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	activation by organism of defense-related symbiont salicylic acid-mediated signal transduction pathway|positive regulation by organism of defense-related symbiont salicylic acid-mediated signal transduction pathway|activation by organism of defense-related symbiont SA-mediated signal transduction pathway|induction by organism of defense-related symbiont SA-mediated signal transduction pathway|induction by organism of defense-related symbiont salicylic acid-mediated signal transduction pathway|upregulation by organism of defense-related symbiont SA-mediated signal transduction pathway|positive regulation by organism of defense-related symbiont SA-mediated signal transduction pathway|upregulation by organism of defense-related symbiont salicylic acid-mediated signal transduction pathway					This term was made obsolete because it does not represent a real biological process.					True			biological_process											owl:Class	
GO:0004172	biolink:NamedThing	obsolete ecdysteroid UDP-glucosyl/UDP-glucuronosyl transferase activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	ecdysteroid UDP-glucosyl/UDP-glucuronosyl transferase activity					This term was made obsolete because it represents two molecular functions.	GO:0050488				True			molecular_function											owl:Class	
GO:0043216	biolink:NamedThing	obsolete ATPase-coupled daunorubicin transmembrane transporter activity	OBSOLETE. Catalysis of the reaction: ATP + H2O + daunorubicin(in) = ADP + phosphate + daunorubicin(out).	tmpzr1t_l9r_go_relaxed.owl	ATP-dependent daunorubicin transmembrane transporter activity|daunorubicin-transporting ATPase activity|daunorubicin ABC transporter				RHEA:33147	This term was obsoleted because it represents a substrate-specific version of the general term GO:0008559 ATPase-coupled xenobiotic transmembrane transporter activity.	GO:0008559				True			molecular_function											owl:Class	
GO:0031684	biolink:NamedThing	obsolete heterotrimeric G-protein complex cycle	OBSOLETE. The series of molecular events that generate a signal through the activation of G-protein subunits and recycling of these subunits.	tmpzr1t_l9r_go_relaxed.owl						The reason for obsoleting is that it is an arbitrary grouping term that groups the molecular functions required for the G-protein complex cycle, and this is not a bona fide biological process.					True			biological_process											owl:Class	
GO:0030402	biolink:NamedThing	obsolete matrilysin-2 activity	OBSOLETE. Was not defined before being made obsolete.	tmpzr1t_l9r_go_relaxed.owl	MMP-26|matrix metalloproteinase 26|matrilysin-2 activity			GO:0004222		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0075116	biolink:NamedThing	obsolete induction by symbiont of host transmembrane receptor-mediated cAMP signal transduction	OBSOLETE. Any process in which the symbiont activates, maintains or increases the frequency, rate or extent of host transmembrane receptor-mediated cAMP signal transduction. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	promotion by symbiont of host transmembrane receptor-mediated cAMP signal transduction|positive regulation by symbiont of host transmembrane receptor-mediated cAMP signal transduction|stimulation by symbiont of host transmembrane receptor-mediated cAMP signal transduction|upregulation by symbiont of host transmembrane receptor-mediated cAMP signal transduction|activation by symbiont of host transmembrane receptor-mediated cAMP signal transduction|positive regulation by symbiont of host transmembrane receptor-mediated cAMP signaling					The reason for obsoletion is that there is no evidence that this process exists.					True			biological_process											owl:Class	
GO:0001617	biolink:NamedThing	obsolete growth hormone secretagogue-like receptor activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	growth hormone secretagogue-like receptor activity					This term was made obsolete because it represents a gene product, was not defined, and is named based on protein features.					True			molecular_function											owl:Class	
GO:0106179	biolink:NamedThing	obsolete translocase activity acting on inorganic cations and their chelates	OBSOLETE. Catalysis of the translocation of inorganic cations and their chelates.	tmpzr1t_l9r_go_relaxed.owl					EC:7.2.-.-	This term was made obsolete because the concept of using the non-4 digit EC classes as parent terms for the transporter banch of the onotolgy was consided confusing.		hjd	2019-04-05T15:45:41Z		True			molecular_function											owl:Class	
GO:0060565	biolink:NamedThing	obsolete inhibition of APC-Cdc20 complex activity	OBSOLETE. Any process that prevents the activation of APC-Cdc20 complex activity regulating the mitotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl	inhibition of mitotic anaphase-promoting complex activity|inhibition of APC activity during mitotic cell cycle|inhibition of APC-Cdc20 complex activity|inhibition of cyclosome activity during mitotic cell cycle|inhibition of APC/C activity during mitotic cell cycle					This term was made obsolete because it was not clearly defined and thus used incorrectly in annotation.	GO:1990948	dph	2009-04-29T02:29:31Z		True			biological_process											owl:Class	
GO:0075213	biolink:NamedThing	obsolete negative regulation of transmembrane receptor-mediated cAMP signal transduction in response to host	OBSOLETE. Any process in which the symbiont organism stops, prevents, or reduces the frequency, rate or extent of its symbiont transmembrane receptor-mediated cAMP signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of symbiont transmembrane receptor-mediated cAMP signal transduction in response to host					This term was obsoleted because there is no evidence that this process exists.					True			biological_process											owl:Class	
GO:0039597	biolink:NamedThing	obsolete induction by virus of host endoribonuclease activity	OBSOLETE. Any viral process that activates or increases the frequency, rate or extent of host endoribonuclease activity.	tmpzr1t_l9r_go_relaxed.owl	viral induction of host RNAse activity	https://github.com/geneontology/go-ontology/issues/21740				This term was obsoleted because it represents a molecular function.		bf	2012-07-04T04:36:49Z		True			biological_process											owl:Class	
GO:0043859	biolink:NamedThing	obsolete cyanophycinase activity	OBSOLETE. Catalysis of the hydrolytic cleavage of multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer) into aspartate-arginine dipeptides.	tmpzr1t_l9r_go_relaxed.owl	cyanophycinase activity			GO:0008236		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0003790	biolink:NamedThing	obsolete actin modulating activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	actin modulating activity					This term was made obsolete because it does not make sense.	GO:0030036				True			molecular_function											owl:Class	
GO:1902397	biolink:NamedThing	obsolete detection of stimulus involved in meiotic spindle checkpoint	OBSOLETE. Any detection of stimulus that is involved in meiotic spindle checkpoint.	tmpzr1t_l9r_go_relaxed.owl	stimulus detection involved in meiotic spindle checkpoint|stimulus sensing involved in meiotic spindle checkpoint|perception of stimulus involved in meiotic spindle checkpoint	https://github.com/geneontology/go-ontology/issues/20976				This term was obsoleted because it corresponds to a molecular function.		jl	2013-09-12T12:01:32Z		True			biological_process											owl:Class	
GO:0021866	biolink:NamedThing	obsolete asymmetric radial glial cell division in forebrain	OBSOLETE. The mitotic cell division of a radial glial cell giving rise to a radial glial cell and another cell type.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it represents a GO-CAM model.					True			biological_process											owl:Class	
GO:0000192	biolink:NamedThing	obsolete activation of MAPKK (pseudohyphal growth)	OBSOLETE. Upregulation of a MAP kinase kinase in the context of regulating pseudohyphal or invasive growth.	tmpzr1t_l9r_go_relaxed.owl	activation of MAPKK (pseudohyphal growth)					This term was made obsolete because it is a gene product specific term.					True			biological_process											owl:Class	
GO:0052333	biolink:NamedThing	obsolete modification by organism of cell wall of other organism involved in symbiotic interaction	OBSOLETE. The process in which an organism effects a change in the structure or function of the cell wall of a second organism, where the two organisms are in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	modification by organism of cell wall of other organism during symbiotic interaction|metabolism by organism of cell wall of other organism					This term was obsoleted because it represents an unnecessary grouping class.					True			biological_process											owl:Class	
GO:0005107	biolink:NamedThing	obsolete GPI-linked ephrin	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	GPI-linked ephrin					This term was made obsolete because it refers to a class of gene products.	GO:0046658|GO:0046875				True			molecular_function											owl:Class	
GO:0009489	biolink:NamedThing	obsolete rubredoxin	OBSOLETE. A low molecular weight mononuclear iron protein involved in electron transfer, with an iron tetrahedrally coordinated by the sulfurs of four conserved cysteine residues.	tmpzr1t_l9r_go_relaxed.owl	rubredoxin			GO:0009055		This term was made obsolete because it does not represent a molecular function.					True			molecular_function											owl:Class	
GO:0060630	biolink:NamedThing	obsolete regulation of M/G1 transition of mitotic cell cycle	OBSOLETE. Any process that modulates the rate, frequency, or extent of M/G1 transition of the mitotic cell cycle, the progression from M phase to G1 phase of the mitotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl	regulation of M/G1 transition of mitotic cell cycle					This term was made obsolete because it does not refer to a real biological process.		dph	2009-05-18T02:48:58Z		True			biological_process											owl:Class	
GO:0045194	biolink:NamedThing	obsolete oxidized low-density lipoprotein catabolic process	OBSOLETE. The chemical reactions and pathways resulting in the breakdown of oxidized low-density lipoproteins.	tmpzr1t_l9r_go_relaxed.owl	Ox-LDL catabolism|oxidized low-density lipoprotein breakdown|oxidized low-density lipoprotein degradation|oxidized low-density lipoprotein catabolism|oxidized low-density lipoprotein catabolic process|Ox-LDL catabolic process					This term was made obsolete because low-density lipoprotein is a macromolecular complex, not a single class of molecule; its degradation involves the dissociation of non-covalently attached constituents as well as some breaking and reforming of covalent bonds.					True			biological_process											owl:Class	
GO:0030383	biolink:NamedThing	obsolete host-pathogen interaction	OBSOLETE. Any interaction between a pathogen and its host organism.	tmpzr1t_l9r_go_relaxed.owl	host-pathogen interaction					This term was made obsolete because more appropriate terms were created.	GO:0044403				True			biological_process											owl:Class	
GO:0015348	biolink:NamedThing	obsolete prostaglandin/thromboxane transporter activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	prostaglandin/thromboxane transporter activity					This term was made obsolete because it represents a multifunctional gene product.	GO:0015132|GO:0008028				True			molecular_function											owl:Class	
GO:0046561	biolink:NamedThing	obsolete penicillopepsin activity	OBSOLETE. Catalysis of the hydrolysis of proteins with broad specificity similar to that of pepsin A, preferring hydrophobic residues at P1 and P1', but also cleaving Gly20-Glu in the B chain of insulin. Clots milk, and activates trypsinogen.	tmpzr1t_l9r_go_relaxed.owl	Penicillium cyclopium acid proteinase activity|Penicillium caseicolum aspartic proteinase activity|Penicillium roqueforti acid proteinase activity|Penicillium janthinellum aspartic proteinase activity|Penicillium duponti aspartic proteinase activity|Penicillium janthinellum acid proteinase activity|penicillopepsin activity|Penicillium citrinum aspartic proteinase activity|Penicillium citrinum acid proteinase activity|Penicillium expansum aspartic proteinase activity|Penicillium expansum acid proteinase activity|Penicillium janthinellum aspartic protease activity|Penicillium aspartic proteinase activity|acid protease A|peptidase A activity			GO:0004190		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0052243	biolink:NamedThing	obsolete chemotaxis on or near other organism involved in symbiotic interaction	OBSOLETE. The directed movement of a motile cell or organism in response to a specific chemical concentration gradient on or near a second organism, where the two organisms are in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	chemotaxis on or near other organism during symbiotic interaction	https://github.com/geneontology/go-ontology/issues/18819				This term was obsoleted because it represents both a process and a location.					True			biological_process											owl:Class	
GO:0060899	biolink:NamedThing	obsolete regulation of transcription involved in eye field cell fate commitment of camera-type eye	OBSOLETE. Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the commitment of a neurectodermal cell to a specialized neurectodermal cell that will give rise to the optic vesicle.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it represents a GO-CAM model.	GO:0006357|GO:0060898	dph	2009-08-13T02:11:48Z		True			biological_process											owl:Class	
GO:0045768	biolink:NamedThing	obsolete positive regulation of anti-apoptosis	OBSOLETE. Any process that activates or increases the frequency, rate or extent of anti-apoptosis.	tmpzr1t_l9r_go_relaxed.owl	upregulation of anti-apoptosis|up-regulation of anti-apoptosis|activation of anti-apoptosis|up regulation of anti-apoptosis|positive regulation of anti-apoptosis|stimulation of anti-apoptosis					This term was made obsolete because it was ill-defined.					True			biological_process											owl:Class	
GO:1902541	biolink:NamedThing	obsolete multi-organism micropinocytosis	OBSOLETE. A micropinocytosis which involves another organism.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/21459				This term was obsoleted because there is no evidence that this process exists.		bf	2013-12-02T14:26:39Z		True			biological_process											owl:Class	
GO:0008571	biolink:NamedThing	obsolete non-chaperonin molecular chaperone ATPase activity	OBSOLETE. Catalysis of the reaction: ATP + H2O = ADP + phosphate. This is a highly diverse group of enzymes that perform many functions that are similar to those of chaperonins. They comprise a number of heat-shock-cognate proteins. They are also active in clathrin uncoating and in the oligomerization of actin.	tmpzr1t_l9r_go_relaxed.owl	non-chaperonin molecular chaperone ATPase activity			GO:0016887		This term was made obsolete because it represents a class of gene products.	GO:0006457				True			molecular_function											owl:Class	
GO:1901205	biolink:NamedThing	obsolete negative regulation of adrenergic receptor signaling pathway involved in heart process	OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of a cardiac adrenergic receptor signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of adrenergic receptor signalling pathway involved in heart process|inhibition of adrenergic receptor signaling pathway involved in heart process|down regulation of beta-adrenergic receptor signalling pathway involved in heart process|down-regulation of beta-adrenergic receptor signalling pathway involved in heart process|down regulation of adrenergic receptor signaling pathway involved in heart process|inhibition of adrenergic receptor signalling pathway involved in heart process|downregulation of adrenergic receptor signalling pathway involved in heart process|downregulation of adrenergic receptor signaling pathway involved in heart process|downregulation of beta-adrenergic receptor signalling pathway involved in heart process|inhibition of beta-adrenergic receptor signalling pathway involved in heart process|down-regulation of adrenergic receptor signaling pathway involved in heart process|negative regulation of beta-adrenergic receptor signalling pathway involved in heart process|down regulation of adrenergic receptor signalling pathway involved in heart process|negative regulation of adrenergic receptor signalling pathway involved in heart process	https://github.com/geneontology/go-ontology/issues/14733				This term was obsoleted because it is not precise enough. We must specify if the ACA-activating or ACA inhibiting pathway is the target of the regulation.		hjd	2012-07-30T18:33:14Z		True			biological_process											owl:Class	
GO:0085021	biolink:NamedThing	obsolete modification by symbiont of host morphology or physiology via protein secreted by type I secretion system	OBSOLETE. The process in which an organism effects a change in the structure or function of its host organism, mediated by a substance secreted by a type I secretion system in the organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it conflated the process in which a gene product is involved with the secretion system by which it reaches its target.		jl	2010-07-09T03:20:44Z		True			biological_process											owl:Class	
GO:0000114	biolink:NamedThing	obsolete regulation of transcription involved in G1 phase of mitotic cell cycle	OBSOLETE. Any process that regulates transcription such that the target genes are transcribed as part of the G1 phase of the mitotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl	regulation of transcription from RNA polymerase II promoter during G1 phase of cell cycle|regulation of transcription involved in G1 phase of mitotic cell cycle|G1-specific transcription in mitotic cell cycle					This term was made obsolete because it is unclear exactly what it means. It could mean either 'regulation of transcription during phase X' or 'regulation of transition between phase X and phase Y'.	GO:0006357|GO:0000083				True			biological_process											owl:Class	
GO:0052247	biolink:NamedThing	obsolete positive energy taxis in other organism involved in symbiotic interaction	OBSOLETE. The directed movement of a motile cell or organism within a second organism towards a higher level of a physical stimulus involved in energy generation, such as light, oxygen, and oxidizable substrates, where the two organisms are in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	positive energy taxis in other organism during symbiotic interaction|positive energy taxis within other organism during symbiotic interaction	https://github.com/geneontology/go-ontology/issues/18819				This term was obsoleted because it represents both a process and a location.					True			biological_process											owl:Class	
GO:0071429	biolink:NamedThing	obsolete snRNA-containing ribonucleoprotein complex export from nucleus	OBSOLETE. The directed movement of a ribonucleoprotein complex that contains small nuclear RNA from the nucleus to the cytoplasm.	tmpzr1t_l9r_go_relaxed.owl	snRNA-containing RNP export from nucleus|snRNA-containing ribonucleoprotein complex export from cell nucleus|snRNA-containing ribonucleoprotein complex nucleus export|snRNA-containing ribonucleoprotein complex transport from nucleus to cytoplasm	https://github.com/geneontology/go-ontology/issues/22246				This term has been obsoleted because it represents the transport of a carrier bound to its substrate.		mah	2009-12-16T10:15:38Z		True			biological_process											owl:Class	
GO:0006502	biolink:NamedThing	obsolete C-terminal protein prenylation	OBSOLETE. The covalent or non-covalent attachment of a prenyl group to the carboxy-terminus of a protein; geranyl, farnesyl, or geranylgeranyl groups may be added.	tmpzr1t_l9r_go_relaxed.owl	C-terminal protein prenylation			GO:0018342		This term was made obsolete because the process is not exclusive to the carboxy-terminus of a protein.					True			biological_process											owl:Class	
GO:0006806	biolink:NamedThing	obsolete insecticide resistance	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	insecticide resistance			GO:0017085		This term was made obsolete because 'resistance' implies a phenotype rather than a biological process.					True			biological_process											owl:Class	
GO:0008248	biolink:NamedThing	obsolete pre-mRNA splicing factor activity	OBSOLETE. An activity involved in the removal of an intron from a pre-mRNA.	tmpzr1t_l9r_go_relaxed.owl	pre-mRNA splicing factor activity					This term was made obsolete because it describes a biological process.	GO:0008380				True			molecular_function											owl:Class	
GO:0052050	biolink:NamedThing	obsolete interaction with host via substance secreted by type IV secretion system	OBSOLETE. An interaction with the host organism mediated by a substance secreted by the other organism by a type IV secretion system. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it conflated the process in which a gene product is involved with the secretion system by which it reaches its target.					True			biological_process											owl:Class	
GO:0031079	biolink:NamedThing	obsolete picornain 3C activity	OBSOLETE. Catalysis of the selective cleavage of GlnGly bond in the poliovirus polyprotein. In other picornavirus reactions Glu may be substituted for Gln, and Ser or Thr for Gly.	tmpzr1t_l9r_go_relaxed.owl	picornavirus endopeptidase 3C activity|poliovirus protease 3C activity|coxsackievirus 3C proteinase activity|rhinovirus proteinase 3C|hepatitis A virus 3C proteinase activity|picornain 3C activity|foot-and-mouth protease 3C activity|tomato ringspot nepovirus 3C-related protease|3C protease activity|poliovirus proteinase 3C|rhinovirus protease 3C activity|cysteine proteinase 3C|foot-and-mouth-disease virus proteinase 3C|protease 3C|3C proteinase activity			GO:0004197		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0036044	biolink:NamedThing	obsolete protein malonylation	OBSOLETE. The modification of a protein amino acid by the addition of a malonyl (CO-CH2-CO) group.	tmpzr1t_l9r_go_relaxed.owl	protein malonylation			GO:0044394		This term was made obsolete because it accidentally shared the same ID as negative regulation of isopentenyl diphosphate biosynthetic process, mevalonate pathway by negative regulation of hydroxymethylglutaryl-CoA reductase (NADPH) activity. New id is GO:0044394.					True			biological_process											owl:Class	
GO:0004186	biolink:NamedThing	obsolete carboxypeptidase C activity	OBSOLETE. Catalysis of the release of a C-terminal amino acid with a broad specificity.	tmpzr1t_l9r_go_relaxed.owl	vacuolar carboxypeptidase Y|carboxypeptidase Y activity|lysosomal protective protein activity|deamidase|serine-type carboxypeptidase I activity|carboxypeptidase C activity|serine carboxypeptidase I activity|cathepsin A activity|lysosomal carboxypeptidase A			GO:0004185		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0050444	biolink:NamedThing	obsolete aquacobalamin reductase (NADPH) activity	OBSOLETE. Catalysis of the reaction: 2 cob(II)alamin + NADP+ = 2 aquacob(III)alamin + NADPH + H+.	tmpzr1t_l9r_go_relaxed.owl	NADPH:aquacob(III)alamin oxidoreductase activity|cob(II)alamin:NADP+ oxidoreductase activity|aquacobalamin (reduced nicotinamide adenine dinucleotide phosphate) activity|NADPH-linked aquacobalamin reductase activity|aquacobalamin (reduced nicotinamide adenine dinucleotide phosphate) reductase activity|NADPH2:aquacob(III)alamin oxidoreductase activity	https://github.com/geneontology/go-ontology/issues/20679			RHEA:20752|MetaCyc:AQUACOBALAMIN-REDUCTASE-NADPH-RXN|EC:1.16.1.5	The term was obsoleted because it is not known to be catalyzed by any gene product.					True			molecular_function											owl:Class	
GO:0051440	biolink:NamedThing	obsolete regulation of ubiquitin-protein ligase activity involved in meiotic cell cycle	OBSOLETE. A cell cycle process that modulates the frequency, rate or extent of ubiquitin ligase activity during the meiotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl	meiotic anaphase-promoting complex regulator|meiotic ubiquitin ligase regulator|meiotic ubiquitin-protein ligase regulator|regulation of ubiquitin ligase activity during meiotic cell cycle|regulation of ubiquitin-protein ligase activity during meiotic cell cycle|meiotic SCF complex regulator|meiotic APC regulator	https://github.com/geneontology/go-ontology/issues/15196				This term was obsoleted because it should be captured as a GO-CAM model.					True			biological_process											owl:Class	
GO:0004444	biolink:NamedThing	obsolete inositol-1,4,5-trisphosphate 1-phosphatase	OBSOLETE. The removal of a phosphate group from the carbon-1 position of D-myo-inositol 1,4,5-trisphosphate.	tmpzr1t_l9r_go_relaxed.owl	inositol-1,4,5-trisphosphate 1-phosphatase					This term was made obsolete because the existence of this function has not been established.	GO:0046030				True			molecular_function											owl:Class	
GO:0019078	biolink:NamedThing	obsolete lytic viral budding	OBSOLETE. A form of viral release in which the viral particles bud out through cellular membranes, resulting in cell lysis. It is also a form of viral envelopment.	tmpzr1t_l9r_go_relaxed.owl	lytic viral budding					This term was made obsolete because it does not appear to correspond to a real biological process.					True			biological_process											owl:Class	
GO:0004184	biolink:NamedThing	obsolete lysine carboxypeptidase activity	OBSOLETE. Catalysis of the reaction: peptidyl-L-lysine (or peptidyl-L-arginine) + H2O = peptide + L-lysine (or L-arginine). Release of a C-terminal basic amino acid, preferentially lysine; inactivates bradykinin and anaphylatoxins in blood plasma.	tmpzr1t_l9r_go_relaxed.owl	kininase Ia|lysine carboxypeptidase activity|CPase N|creatinine kinase convertase activity|peptidyl-L-lysine(-L-arginine) hydrolase|anaphylatoxin inactivator activity|creatine kinase conversion factor|bradykinin-decomposing enzyme|carboxypeptidase N activity|bradykinase activity|hippuryllysine hydrolase activity|kininase I activity|lysine (arginine) carboxypeptidase activity|arginine carboxypeptidase activity|plasma carboxypeptidase B|lysine(arginine) carboxypeptidase activity			GO:0004181		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0042598	biolink:NamedThing	obsolete vesicular fraction	OBSOLETE. Any of the small, heterogeneous, artifactual, vesicular particles that are formed when some cells are homogenized.	tmpzr1t_l9r_go_relaxed.owl	vesicular fraction					This term was made obsolete because it refers to a cell fractionation experimental result and not a bona fide cellular component.	GO:0031982				True			cellular_component											owl:Class	
GO:0030190	biolink:NamedThing	obsolete chaperone inhibitor activity	OBSOLETE. Stops, prevents or reduces the activity of a molecular chaperone.	tmpzr1t_l9r_go_relaxed.owl	chaperone inhibitor activity					This term was made obsolete because it refers to a obsolete molecular function term, 'chaperone activity'.	GO:0051082|GO:0051787|GO:0006457				True			molecular_function											owl:Class	
GO:0003702	biolink:NamedThing	obsolete RNA polymerase II transcription factor activity	OBSOLETE. Functions to initiate or regulate RNA polymerase II transcription.	tmpzr1t_l9r_go_relaxed.owl	RNA polymerase II transcription factor activity					This term was obsoleted because it is essentially identical to a Process term (specifically the Biological Process term which has been selected as a term to consider for reannotation), i.e. it is defined only in terms of the process it acts in and it does NOT convey any information about the molecular nature of the function or whether the function is based on binding DNA, on interacting with other proteins, or some other mechanism. To transfer all annotations without review, the BP term indicated is considered to be equivalent and thus the only appropriate destination for all annotations. To reannotate to a MF term, you will probably need to revisit the original literature or other primary data because this "MF" term was not defined in terms of mechanism of action and there are multiple possibilities in the revised MF structure. In reannotation, please also consider descendent terms of the suggested MF terms as a more specific term may be more appropriate than the MF terms indicated. Please be aware that you may wish to request a new term if the mechanism of action of this gene product is not yet represented or if you are annotating for an RNAP different than one for which there is a specific suggested term. Also note that if there is no information about how the gene product acts, it may be appropriate to annotate to the root term for molecular_function.	GO:0006366|GO:0000981				True			molecular_function											owl:Class	
GO:0035528	biolink:NamedThing	obsolete UDP-N-acetylglucosamine biosynthesis involved in chitin biosynthesis	OBSOLETE. The chemical reactions and pathways resulting in the formation of UDP-N-acetylglucosamine, a substance composed of N-acetylglucosamine in glycosidic linkage with uridine diphosphate, that contribute to the biosynthesis of chitin.	tmpzr1t_l9r_go_relaxed.owl	UDP-GlcNAc biosynthetic process involved in chitin biosynthetic process|UDP-N-acetylglucosamine synthesis involved in chitin biosynthesis|UDP-GlcNAc biosynthetic process involved in chitin biosynthesis|UDP-N-acetylglucosamine anabolism involved in chitin biosynthesis|UDP-GlcNAc biosynthesis involved in chitin biosynthesis|UDP-N-acetylglucosamine formation involved in chitin biosynthesis|UDP-N-acetylglucosamine biosynthetic process involved in chitin biosynthetic process	https://github.com/geneontology/go-ontology/issues/18200				This term was obsoleted because it does not represent a specific pathway.		bf	2010-05-05T04:49:49Z		True			biological_process											owl:Class	
GO:0052349	biolink:NamedThing	obsolete positive regulation by organism of defense-related symbiont reactive oxygen species production	OBSOLETE. Any process in which an organism activates, maintains or increases the frequency, rate or extent of the production of reactive oxygen species as part of the defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	positive regulation by organism of defense-related symbiont oxidative burst|positive regulation by organism of defense-related symbiont AOS production|positive regulation by organism of defense-related symbiont ROS production|positive regulation by organism of defense-related symbiont ROI production|positive regulation by organism of defense-related symbiont respiratory burst|positive regulation by organism of defense-related symbiont reactive oxygen species production|positive regulation by organism of defense-related symbiont reactive oxidative species production|positive regulation by organism of defense-related symbiont reactive oxygen intermediate production|positive regulation by organism of defense-related symbiont metabolic burst|positive regulation by organism of defense-related symbiont active oxygen species production					This term was made obsolete because it does not represent a real biological process.					True			biological_process											owl:Class	
GO:1901225	biolink:NamedThing	obsolete negative regulation of transcription from RNA polymerase II promoter involved in heart development	OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of regulation of transcription from RNA polymerase II promoter involved in heart development.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of regulation of gene-specific transcription from RNA polymerase II promoter involved in cardiac development|inhibition of regulation of gene-specific transcription from RNA polymerase II promoter involved in heart development|downregulation of regulation of transcription from RNA polymerase II promoter, global involved in dorsal vessel development|down regulation of regulation of gene-specific transcription from RNA polymerase II promoter involved in dorsal vessel development|down-regulation of regulation of transcription from RNA polymerase II promoter involved in cardiac development|inhibition of regulation of gene-specific transcription from RNA polymerase II promoter involved in cardiac development|down regulation of regulation of transcription from RNA polymerase II promoter involved in cardiac development|down regulation of regulation of transcription from RNA polymerase II promoter, global involved in cardiac development|down regulation of regulation of global transcription from Pol II promoter involved in cardiac development|inhibition of global transcription regulation from Pol II promoter involved in dorsal vessel development|down-regulation of global transcription regulation from Pol II promoter involved in cardiac development|down regulation of regulation of global transcription from Pol II promoter involved in heart development|negative regulation of regulation of transcription from Pol II promoter involved in dorsal vessel development|inhibition of regulation of global transcription from Pol II promoter involved in cardiac development|inhibition of regulation of transcription from Pol II promoter involved in cardiac development|downregulation of regulation of transcription from Pol II promoter involved in dorsal vessel development|negative regulation of regulation of transcription from RNA polymerase II promoter involved in dorsal vessel development|negative regulation of global transcription regulation from Pol II promoter involved in cardiac development|downregulation of regulation of global transcription from Pol II promoter involved in cardiac development|down regulation of global transcription regulation from Pol II promoter involved in dorsal vessel development|down regulation of regulation of transcription from Pol II promoter involved in dorsal vessel development|down-regulation of regulation of transcription from RNA polymerase II promoter involved in heart development|inhibition of regulation of transcription from RNA polymerase II promoter involved in dorsal vessel development|inhibition of regulation of transcription from RNA polymerase II promoter involved in heart development|down-regulation of regulation of transcription from RNA polymerase II promoter, global involved in heart development|down-regulation of regulation of transcription from RNA polymerase II promoter involved in dorsal vessel development|down-regulation of global transcription regulation from Pol II promoter involved in dorsal vessel development|down-regulation of regulation of transcription from RNA polymerase II promoter, global involved in cardiac development|inhibition of regulation of transcription from RNA polymerase II promoter, global involved in dorsal vessel development|down-regulation of global transcription regulation from Pol II promoter involved in heart development|down-regulation of regulation of global transcription from Pol II promoter involved in heart development|inhibition of regulation of transcription from Pol II promoter involved in heart development|down regulation of regulation of gene-specific transcription from RNA polymerase II promoter involved in heart development|down regulation of regulation of transcription from RNA polymerase II promoter, global involved in heart development|negative regulation of regulation of transcription from RNA polymerase II promoter, global involved in dorsal vessel development|down regulation of regulation of transcription from Pol II promoter involved in cardiac development|downregulation of regulation of transcription from RNA polymerase II promoter involved in heart development|negative regulation of global transcription regulation from Pol II promoter involved in dorsal vessel development|down-regulation of regulation of gene-specific transcription from RNA polymerase II promoter involved in dorsal vessel development|inhibition of global transcription regulation from Pol II promoter involved in cardiac development|down regulation of global transcription regulation from Pol II promoter involved in cardiac development|downregulation of regulation of gene-specific transcription from RNA polymerase II promoter involved in dorsal vessel development|downregulation of regulation of global transcription from Pol II promoter involved in dorsal vessel development|down regulation of regulation of global transcription from Pol II promoter involved in dorsal vessel development|inhibition of regulation of transcription from RNA polymerase II promoter, global involved in cardiac development|down-regulation of regulation of transcription from Pol II promoter involved in heart development|downregulation of regulation of transcription from RNA polymerase II promoter involved in cardiac development|downregulation of global transcription regulation from Pol II promoter involved in heart development|downregulation of global transcription regulation from Pol II promoter involved in cardiac development|down regulation of regulation of transcription from RNA polymerase II promoter involved in heart development|inhibition of global transcription regulation from Pol II promoter involved in heart development|downregulation of regulation of transcription from RNA polymerase II promoter, global involved in heart development|inhibition of regulation of global transcription from Pol II promoter involved in dorsal vessel development|inhibition of regulation of gene-specific transcription from RNA polymerase II promoter involved in dorsal vessel development|down-regulation of regulation of global transcription from Pol II promoter involved in cardiac development|down-regulation of regulation of gene-specific transcription from RNA polymerase II promoter involved in cardiac development|downregulation of global transcription regulation from Pol II promoter involved in dorsal vessel development|down regulation of regulation of gene-specific transcription from RNA polymerase II promoter involved in cardiac development|negative regulation of regulation of global transcription from Pol II promoter involved in heart development|downregulation of regulation of global transcription from Pol II promoter involved in heart development|down regulation of regulation of transcription from Pol II promoter involved in heart development|down regulation of regulation of transcription from RNA polymerase II promoter, global involved in dorsal vessel development|negative regulation of regulation of gene-specific transcription from RNA polymerase II promoter involved in dorsal vessel development|down-regulation of regulation of transcription from RNA polymerase II promoter, global involved in dorsal vessel development|negative regulation of transcription from RNA polymerase II promoter involved in heart development|negative regulation of regulation of transcription from RNA polymerase II promoter, global involved in cardiac development|inhibition of regulation of transcription from Pol II promoter involved in dorsal vessel development|negative regulation of regulation of transcription from Pol II promoter involved in heart development|negative regulation of regulation of transcription from Pol II promoter involved in cardiac development|inhibition of regulation of global transcription from Pol II promoter involved in heart development|downregulation of regulation of gene-specific transcription from RNA polymerase II promoter involved in cardiac development|downregulation of regulation of gene-specific transcription from RNA polymerase II promoter involved in heart development|down-regulation of regulation of transcription from Pol II promoter involved in dorsal vessel development|negative regulation of regulation of global transcription from Pol II promoter involved in cardiac development|negative regulation of regulation of transcription from RNA polymerase II promoter involved in cardiac development|negative regulation of global transcription regulation from Pol II promoter involved in heart development|down regulation of global transcription regulation from Pol II promoter involved in heart development|negative regulation of regulation of gene-specific transcription from RNA polymerase II promoter involved in heart development|down-regulation of regulation of transcription from Pol II promoter involved in cardiac development|downregulation of regulation of transcription from RNA polymerase II promoter, global involved in cardiac development|inhibition of regulation of transcription from RNA polymerase II promoter, global involved in heart development|negative regulation of regulation of transcription from RNA polymerase II promoter, global involved in heart development|downregulation of regulation of transcription from Pol II promoter involved in heart development|downregulation of regulation of transcription from RNA polymerase II promoter involved in dorsal vessel development|inhibition of regulation of transcription from RNA polymerase II promoter involved in cardiac development|negative regulation of regulation of global transcription from Pol II promoter involved in dorsal vessel development|down-regulation of regulation of gene-specific transcription from RNA polymerase II promoter involved in heart development|down regulation of regulation of transcription from RNA polymerase II promoter involved in dorsal vessel development|downregulation of regulation of transcription from Pol II promoter involved in cardiac development|down-regulation of regulation of global transcription from Pol II promoter involved in dorsal vessel development					This term was obsoleted at the TermGenie Gatekeeper stage.	GO:0007507|GO:0000122	rl	2012-08-07T07:04:07Z		True			biological_process											owl:Class	
GO:0005530	biolink:NamedThing	obsolete lectin	OBSOLETE. Lectins are proteins obtained particularly from the seeds of leguminous plants, but also from many other plant and animal sources, that have binding sites for specific mono or oligosaccharides in cell walls or membranes. They thereby change the physiology of the membrane to cause agglutination, mitosis, or other biochemical changes in the cell.	tmpzr1t_l9r_go_relaxed.owl	lectin					This term was made obsolete because it refers to a class of gene products.	GO:0030246|GO:0007157				True			molecular_function											owl:Class	
GO:0075339	biolink:NamedThing	obsolete positive regulation of growth or development of symbiont during interaction with host	OBSOLETE. Any process that activates or increases the frequency, rate or extent of the increase in size or mass of an organism, or the progression of an organism from an initial condition to a later condition, occurring in, on or near the exterior of its host organism.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of growth or development of symbiont during interaction with host					This term was made obsolete because it contained a conjunction (or).					True			biological_process											owl:Class	
GO:0052447	biolink:NamedThing	obsolete modulation by organism of symbiont ethylene-mediated defense response	OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of the ethylene-mediated defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	modulation by organism of symbiont ethylene-mediated defense response					This term was made obsolete because it does not represent a real biological process.					True			biological_process											owl:Class	
GO:0051818	biolink:NamedThing	obsolete disruption of cells of other organism involved in symbiotic interaction	OBSOLETE. A process in which an organism has a negative effect on the functioning of the second organism's cells, where the two organisms are in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	disruption of cells of other organism during symbiotic interaction					This term was obsoleted because it represents an unnecessary grouping class.					True			biological_process											owl:Class	
GO:0019791	biolink:NamedThing	obsolete FAT10 hydrolase activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	FAT10 hydrolase activity					This term was made obsolete because it cannot be determined what its intended meaning was, because the term name is not found in the literature.	GO:0019783				True			molecular_function											owl:Class	
GO:0052502	biolink:NamedThing	obsolete positive regulation by host of defense-related symbiont MAP kinase-mediated signal transduction pathway	OBSOLETE. Any process in which an organism activates, maintains or increases the frequency, rate or extent of symbiont MAP kinase-mediated signal transduction pathways during the symbiont defense response. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	upregulation by host of defense-related symbiont MAP kinase-mediated signal transduction pathway|upregulation by organism of defense-related symbiont MAP kinase-mediated signal transduction pathway|stimulation by host of defense-related symbiont MAP kinase-mediated signal transduction pathway|up-regulation by host of defense-related symbiont MAP kinase-mediated signal transduction pathway|activation by organism of defense-related symbiont MAP kinase-mediated signal transduction pathway|induction by organism of defense-related symbiont MAP kinase-mediated signal transduction pathway|positive regulation by organism of defense-related symbiont MAPK-mediated signal transduction pathway|up regulation by host of defense-related symbiont MAP kinase-mediated signal transduction pathway|activation by host of defense-related symbiont MAP kinase-mediated signal transduction pathway|positive regulation by organism of defense-related symbiont mitogen-activated protein kinase-mediated signal transduction pathway					The reason for obsoletion is that there is no evidence that the host can modulate or regulate a symbiont's signal transduction pathway.					True			biological_process											owl:Class	
GO:1900382	biolink:NamedThing	obsolete regulation of thiamine biosynthetic process by regulation of transcription from RNA polymerase II promoter	OBSOLETE. A regulation of transcription from RNA polymerase II promoter that results in regulation of thiamine biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of thiamine formation by regulation of transcription from RNA polymerase II promoter|regulation of thiamine biosynthesis by regulation of transcription from RNA polymerase II promoter|regulation of thiamin biosynthetic process by regulation of transcription from RNA polymerase II promoter|regulation of thiamine synthesis by regulation of transcription from RNA polymerase II promoter|regulation of thiamine anabolism by regulation of transcription from RNA polymerase II promoter					This term was obsoleted because it represents a GO-CAM model.		mah	2012-04-17T04:05:24Z		True			biological_process											owl:Class	
GO:0046909	biolink:NamedThing	obsolete intermembrane transport	OBSOLETE. The directed movement of substances between any membrane of a cell, including the plasma membrane and its regions.	tmpzr1t_l9r_go_relaxed.owl						The reason for obsoletion is that this term was incorrectly named, defined, and placed in the ontology, and thus had been used to annotate two unrelated processes of [intermembrane lipid transfer] and processes related to [vesicular transport]. It was also inappropriately used as the parent term for [protein transport from ciliary membrane to plasma membrane], which has already been moved to an appropriate location as a child of [protein transport within lipid bilayer].	GO:0120009|GO:0016192				True			biological_process											owl:Class	
GO:0005624	biolink:NamedThing	obsolete membrane fraction	OBSOLETE. That fraction of cells, prepared by disruptive biochemical methods, that includes the plasma and other membranes.	tmpzr1t_l9r_go_relaxed.owl	membrane fraction					This term was made obsolete because it refers to a cell fractionation experimental result and not a bona fide cellular component.	GO:0016020				True			cellular_component											owl:Class	
GO:0106195	biolink:NamedThing	obsolete translocase activty acting on inorganic anions linked to oxidoreductase reactions	OBSOLETE. Catalysis of the translocation of inorganic anions linked to oxidoreductase reactions.	tmpzr1t_l9r_go_relaxed.owl					EC:7.3.1.-	This term was made obsolete because the concept of using the non-4 digit EC classes as parent terms for the transporter banch of the onotolgy was consided confusing.		hjd	2019-05-08T18:13:05Z		True			molecular_function											owl:Class	
GO:0040030	biolink:NamedThing	obsolete regulation of molecular function, epigenetic	OBSOLETE. Any heritable epigenetic process that modulates the frequency, rate or extent of protein function by self-perpetuating conformational conversions of normal proteins in healthy cells. This is distinct from, though mechanistically analogous to, disease states associated with prion propagation and amyloidogenesis. A single protein, if it carries a glutamine/asparagine-rich ('prion') domain, can sometimes stably exist in at least two distinct physical states, each associated with a different phenotype; propagation of one of these traits is achieved by a self-perpetuating change in the protein from one form to the other, mediated by conformational changes in the glutamine/asparagine-rich domain. Prion domains are both modular and transferable to other proteins, on which they can confer a heritable epigenetic alteration of function; existing bioinformatics data indicate that they are rare in non-eukarya, but common in eukarya.	tmpzr1t_l9r_go_relaxed.owl	regulation of protein activity, epigenetic	https://github.com/geneontology/go-ontology/issues/22203				This term was obsoleted because it is not an active process.					True			biological_process											owl:Class	
GO:0032235	biolink:NamedThing	obsolete negative regulation of calcium ion transport via store-operated calcium channel activity	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of calcium ions via a store-operated calcium channel.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of calcium ion transport via store-operated calcium channel|negative regulation of calcium ion transport via store-operated calcium channel activity|negative regulation of store-operated calcium channel activity|negative regulation of calcium transport via store-operated calcium channel|inhibition of calcium ion transport via store-operated calcium channel|downregulation of calcium ion transport via store-operated calcium channel|down regulation of calcium ion transport via store-operated calcium channel					This term was made obsolete because it is ill-defined: channel activities are part of ion transport processes, and not the other way round.	GO:0015279				True			biological_process											owl:Class	
GO:0005489	biolink:NamedThing	obsolete electron transporter activity	OBSOLETE. Enables the directed movement of electrons into, out of, within or between cells.	tmpzr1t_l9r_go_relaxed.owl	cytochrome d|electron transporter activity|respiratory chain cytochrome b6|monoheme class I cytochrome c|flavodoxin|class IIa cytochrome c|nonaheme cytochrome c|cytochrome b|Rieske iron-sulfur protein|diheme class I cytochrome c|cytochrome b5|class IV cytochrome c|high-molecular-weight cytochrome c (hexadecaheme)|class II cytochrome c|flavin-containing electron transporter|class IIb cytochrome c|cytochrome c3 (tetraheme)|cytochrome c7 (triheme)|class III cytochrome c|electron transfer carrier|cytochrome c554|class I cytochrome c			GO:0009055		This term was made obsolete because the activity described by the definition does not exist.					True			molecular_function											owl:Class	
GO:1905924	biolink:NamedThing	obsolete regulation of invadopodium assembly	OBSOLETE. Any process that modulates the frequency, rate or extent of invadopodium assembly.	tmpzr1t_l9r_go_relaxed.owl	regulation of invadopodium formation					This term was made obsolete because an invadopodium is an abnormal structure found in cancerous or transformed cells that is out of scope of GO.		sl	2017-02-08T21:38:30Z		True			biological_process											owl:Class	
GO:0052139	biolink:NamedThing	obsolete negative chemotaxis in host	OBSOLETE. The directed movement of a motile cell or organism towards a lower concentration of a specific chemical within its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	negative chemotaxis within host	https://github.com/geneontology/go-ontology/issues/18819				This term was obsoleted because it represents both a process and a location.					True			biological_process											owl:Class	
GO:0030820	biolink:NamedThing	obsolete regulation of cAMP catabolic process	OBSOLETE. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate).	tmpzr1t_l9r_go_relaxed.owl	regulation of 3',5'-cAMP catabolic process|regulation of cyclic AMP catabolic process|regulation of adenosine 3',5'-cyclophosphate catabolism|regulation of 3',5' cAMP catabolic process|regulation of cAMP degradation|regulation of cAMP breakdown|regulation of cyclic AMP catabolism|regulation of cAMP catabolism|regulation of 3',5' cAMP catabolism|regulation of adenosine 3',5'-cyclophosphate catabolic process|regulation of 3',5'-cAMP catabolism					The reason for obsoletion is that this term represents the regulation of a signaling pathway, not regulation of metabolism.					True			biological_process											owl:Class	
GO:0042153	biolink:NamedThing	obsolete RPTP-like protein binding	OBSOLETE. Binding to proteins with similar structure/function to receptor protein tyrosine phosphatases.	tmpzr1t_l9r_go_relaxed.owl	receptor protein tyrosine phosphatase-like protein binding|RPTP-like protein binding			GO:0005515		This term was made obsolete because it represents binding to an individual protein.					True			molecular_function											owl:Class	
RO:0002305	biolink:NamedThing	causally upstream of, negative effect		tmpzr1t_l9r_go_relaxed.owl					RO:0002305									external									causally_upstream_of,_negative_effect			
GO:0075337	biolink:NamedThing	obsolete positive regulation of growth or development of symbiont on or near host surface	OBSOLETE. Any process that activates or increases the frequency, rate or extent of the symbiont's increase in size or mass, or its progression from an initial condition to a later condition, on or near the cells or tissues of the host organism.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of growth or development of symbiont on or near host surface					This term was made obsolete because it contained a conjunction (or).					True			biological_process											owl:Class	
GO:0001027	biolink:NamedThing	obsolete RNA polymerase III type 1 promoter TFIIIB-type transcription factor activity	OBSOLETE. Binding to an RNA polymerase III (Pol III) complex, typically composed of seventeen subunits, and with another protein, macromolecule, or complex, permitting those molecules to function in a coordinated way. Once recruited to an RNA polymerase III type 1 promoter by TFIIIA-type and TFIIIC-type factors, binds to DNA, recruits RNA polymerase III and facilitates the transition from the closed to the open complex.	tmpzr1t_l9r_go_relaxed.owl	RNA polymerase III type 1 promoter polymerase recruiting transcription factor activity					The reason for obsoletion is that there is a single TFIIIB activity; this is not dependent on the promoter.		krc	2010-08-23T12:50:20Z		True			molecular_function											owl:Class	
GO:1905113	biolink:NamedThing	obsolete positive regulation of centromere clustering at the mitotic nuclear envelope	OBSOLETE. Any process that activates or increases the frequency, rate or extent of centromere clustering at the nuclear envelope.	tmpzr1t_l9r_go_relaxed.owl	activation of kinetochore localization at spindle pole body|up regulation of rabl configuration|activation of kinetochore clustering at SPB|positive regulation of kinetochore localization at spindle pole body|positive regulation of kinetochore clustering at the old mitotic spindle pole body|upregulation of kinetochore clustering at spindle pole body|up-regulation of centromere-SPB clustering|up-regulation of rabl configuration|up regulation of centromere clustering at the nuclear periphery|upregulation of rabl configuration|upregulation of kinetochore clustering at SPB|up-regulation of kinetochore clustering at the old mitotic spindle pole body|up-regulation of kinetochore clustering at spindle pole body|up-regulation of centromere clustering at the nuclear periphery|positive regulation of kinetochore clustering at spindle pole body|upregulation of centromere clustering at the nuclear envelope|up regulation of kinetochore clustering at SPB|activation of rabl configuration|up regulation of kinetochore clustering at the old mitotic spindle pole body|positive regulation of rabl configuration|activation of centromere clustering at the nuclear periphery|positive regulation of centromere-SPB clustering|up-regulation of kinetochore localization at spindle pole body|up regulation of centromere clustering at the nuclear envelope|up-regulation of centromere clustering at the nuclear envelope|up regulation of kinetochore localization at spindle pole body|activation of kinetochore clustering at spindle pole body|upregulation of kinetochore localization at spindle pole body|upregulation of centromere clustering at the nuclear periphery|activation of kinetochore clustering at the old mitotic spindle pole body|upregulation of kinetochore clustering at the old mitotic spindle pole body|positive regulation of centromere clustering at the nuclear periphery|activation of centromere clustering at the nuclear envelope|up-regulation of kinetochore clustering at SPB|activation of centromere-SPB clustering|up regulation of centromere-SPB clustering|up regulation of kinetochore clustering at spindle pole body|upregulation of centromere-SPB clustering|positive regulation of kinetochore clustering at SPB					This term was obsoleted because it represented a phenotype.		al	2016-04-06T16:25:49Z		True			biological_process											owl:Class	
GO:0000363	biolink:NamedThing	obsolete first U12-type spliceosomal transesterification activity	OBSOLETE. Catalysis of the first transesterification reaction of U12-type spliceosomal mRNA splicing. The intron branch site adenosine is the nucleophile attacking the 5' splice site, resulting in cleavage at this position. In cis splicing, this is the step that forms a lariat structure of the intron RNA, which is still joined to the 3' exon. The catalytic site is thought to be formed by U6atac snRNA and/or U2atac snRNA, and/or associated proteins.	tmpzr1t_l9r_go_relaxed.owl	lariat formation, 5'-splice site cleavage|first U12-type spliceosomal transesterification activity			GO:0000384		This term was made obsolete because the activities used in the U2- and U12-type complexes are the same. The cellular component ontology should (and does) represent the two different complexes, but the molecular function ontology should not.					True			molecular_function											owl:Class	
GO:0085003	biolink:NamedThing	obsolete interaction with host via secreted substance released from stylet	OBSOLETE. An interaction with the host organism mediated by a substance released by the other (symbiont) organism via the stylet, a hollow protrusible spear-like structure in the symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl						This term was deprecated because it conflated the process in which a gene product is involved with the secretion system by which it reaches its target.		jl	2010-02-10T02:53:56Z		True			biological_process											owl:Class	
GO:0033666	biolink:NamedThing	obsolete positive regulation of growth or development of symbiont in host	OBSOLETE. Any process by which the symbiont activates, maintains or increases its size or mass or its progression from an initial condition to a later condition, within the cells or tissues of the host organism. The host is defined as the larger of the organisms involved in the symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of invasive growth|positive regulation of growth or development of symbiont in host|up regulation of growth or development of organism within host|positive regulation of growth or development of symbiont within host|upregulation of growth or development of organism within host|up-regulation of growth or development of organism within host					This term was made obsolete because it contained a conjunction (or).	GO:0044129				True			biological_process											owl:Class	
GO:0005696	biolink:NamedThing	obsolete telomere	OBSOLETE. A complex of DNA and protein that seals the end of a chromosome. The telomeric DNA consists of simple tandemly repeated sequences specific for each species. Typically one strand is G-rich and the other C-rich. The G-rich strand forms a 3'-terminal overhang, the length of which varies with species. The single strand overhang is bound by a variety of proteins, including telomere capping proteins that bind to the single-stranded DNA.	tmpzr1t_l9r_go_relaxed.owl	telomere					This term was made obsolete because the definition was too sequence oriented and too restrictive.	GO:0000781|GO:0000782				True			cellular_component											owl:Class	
GO:0005057	biolink:NamedThing	obsolete signal transducer activity, downstream of receptor	OBSOLETE. Conveys a signal from an upstream receptor or intracellular signal transducer, converting the signal into a form where it can ultimately trigger a change in the state or activity of a cell.	tmpzr1t_l9r_go_relaxed.owl	receptor signalling protein activity|intracellular signal transducer activity|receptor signaling protein activity	https://github.com/geneontology/go-ontology/issues/14232				This term was obsoleted because it was not clearly defined.					True			molecular_function											owl:Class	
GO:0010871	biolink:NamedThing	obsolete negative regulation of receptor biosynthetic process	OBSOLETE. Any process that decreases the frequency or rate of receptor biosynthesis. Receptor biosynthesis is the collection of chemical reactions and pathways resulting in the formation of a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/19900				The reason for obsoletion is that those represent specific gene products, and genes annotated to those terms should be annotated to 'regulation of gene expression' or 'regulation of transcription' or some signaling term.					True			biological_process											owl:Class	
GO:0006969	biolink:NamedThing	obsolete melanotic tumor response	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	melanotic mass response|melanotic tumor response					This term was made obsolete because it was undefined and represented an abnormal process.					True			biological_process											owl:Class	
GO:0016735	biolink:NamedThing	obsolete vanadium-iron nitrogenase activity	OBSOLETE. Catalysis of the reaction: 8 reduced ferredoxin + 8 H+ + nitrogen + 16 ATP = 8 oxidized ferredoxin + 2 NH3 + 16 ADP + 16 phosphate.	tmpzr1t_l9r_go_relaxed.owl	vanadium-iron nitrogenase activity					This term was made obsolete because it represents a cellular component.	GO:0016163|GO:0016613				True			molecular_function											owl:Class	
GO:0019717	biolink:NamedThing	obsolete synaptosome	OBSOLETE. Any of the discrete particles (nerve-ending particles) formed from the clublike presynaptic nerve endings that resist disruption and are snapped or torn off their attachments when brain tissue is homogenized in media isosmotic to plasma.	tmpzr1t_l9r_go_relaxed.owl	synaptosome				Wikipedia:Synaptosome	This term was made obsolete because it refers to a result of cell homogenization and not a bona fide cellular component.	GO:0043005				True			cellular_component											owl:Class	
GO:0030800	biolink:NamedThing	obsolete negative regulation of cyclic nucleotide metabolic process	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving cyclic nucleotides.	tmpzr1t_l9r_go_relaxed.owl	down regulation of cyclic nucleotide metabolic process|negative regulation of cyclic nucleotide metabolism|inhibition of cyclic nucleotide metabolic process|down-regulation of cyclic nucleotide metabolic process|downregulation of cyclic nucleotide metabolic process					The reason for obsoletion is that this term represents the regulation of a signaling pathway, not regulation of metabolism.					True			biological_process											owl:Class	
GO:1900529	biolink:NamedThing	obsolete regulation of cell shape involved in cellular response to glucose starvation	OBSOLETE. Any regulation of cell shape that is involved in cellular response to glucose starvation.	tmpzr1t_l9r_go_relaxed.owl	regulation of cell shape involved in cellular response to glucose starvation					This term was obsoleted at the TermGenie Gatekeeper stage.		al	2012-05-08T01:43:38Z		True			biological_process											owl:Class	
GO:0035557	biolink:NamedThing	obsolete intracellular signal transduction involved in cell surface receptor linked signaling	OBSOLETE. The process in which a signal is passed on from a receptor at the cell surface to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell.	tmpzr1t_l9r_go_relaxed.owl	intracellular signaling cascade involved in cell surface receptor linked signaling|intracellular signal transduction involved in cell surface receptor linked signaling|intracellular signaling chain involved in cell surface receptor signaling|intracellular signal transduction involved in cell surface receptor linked signalling					This term was made obsolete because the syntax of the term is incorrect.		bf	2010-05-14T01:31:05Z		True			biological_process											owl:Class	
GO:0004178	biolink:NamedThing	obsolete leucyl aminopeptidase activity	OBSOLETE. Catalysis of the release of an N-terminal amino acid, Xaa-Xbb-, in which Xaa is preferably Leu, but may be other amino acids including Pro although not Arg or Lys, and Xbb may be Pro.	tmpzr1t_l9r_go_relaxed.owl	peptidase S activity|leucine aminopeptidase activity|FTBL proteins|leucyl peptidase activity|aminopeptidase II|leucinamide aminopeptidase activity|leucyl aminopeptidase activity|cathepsin III|cytosol aminopeptidase activity|proteinates FTBL|leucinaminopeptidase activity|L-leucine aminopeptidase activity				MetaCyc:3.4.11.1-RXN|EC:3.4.11.1	This term was made obsolete because it represents a gene product.	GO:0004177|GO:0008235				True			molecular_function											owl:Class	
GO:1900375	biolink:NamedThing	obsolete positive regulation of inositol biosynthetic process by positive regulation of transcription from RNA polymerase II promoter	OBSOLETE. A positive regulation of transcription from RNA polymerase II promoter that results in positive regulation of inositol biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of myo-inositol biosynthetic process by positive regulation of transcription from RNA polymerase II promoter|up regulation of inositol synthesis by positive regulation of transcription from RNA polymerase II promoter|up-regulation of inositol biosynthetic process by positive regulation of transcription from RNA polymerase II promoter|up regulation of inositol biosynthetic process by positive regulation of transcription from RNA polymerase II promoter|upregulation of myo-inositol biosynthetic process by positive regulation of transcription from RNA polymerase II promoter|up regulation of vitamin Bh biosynthesis by positive regulation of transcription from RNA polymerase II promoter|up regulation of inositol formation by positive regulation of transcription from RNA polymerase II promoter|positive regulation of inositol biosynthesis by positive regulation of transcription from RNA polymerase II promoter|activation of myo-inositol biosynthetic process by positive regulation of transcription from RNA polymerase II promoter|positive regulation of myo-inositol biosynthesis by positive regulation of transcription from RNA polymerase II promoter|upregulation of inositol anabolism by positive regulation of transcription from RNA polymerase II promoter|up-regulation of inositol synthesis by positive regulation of transcription from RNA polymerase II promoter|up-regulation of inositol biosynthesis by positive regulation of transcription from RNA polymerase II promoter|positive regulation of vitamin Bh biosynthetic process by positive regulation of transcription from RNA polymerase II promoter|up regulation of inositol biosynthesis by positive regulation of transcription from RNA polymerase II promoter|up regulation of myo-inositol biosynthesis by positive regulation of transcription from RNA polymerase II promoter|positive regulation of inositol anabolism by positive regulation of transcription from RNA polymerase II promoter|activation of inositol biosynthetic process by positive regulation of transcription from RNA polymerase II promoter|up-regulation of myo-inositol biosynthesis by positive regulation of transcription from RNA polymerase II promoter|up-regulation of vitamin Bh biosynthesis by positive regulation of transcription from RNA polymerase II promoter|up-regulation of vitamin Bh biosynthetic process by positive regulation of transcription from RNA polymerase II promoter|activation of vitamin Bh biosynthesis by positive regulation of transcription from RNA polymerase II promoter|upregulation of myo-inositol biosynthesis by positive regulation of transcription from RNA polymerase II promoter|upregulation of inositol synthesis by positive regulation of transcription from RNA polymerase II promoter|activation of inositol synthesis by positive regulation of transcription from RNA polymerase II promoter|up regulation of vitamin Bh biosynthetic process by positive regulation of transcription from RNA polymerase II promoter|up regulation of inositol anabolism by positive regulation of transcription from RNA polymerase II promoter|upregulation of vitamin Bh biosynthetic process by positive regulation of transcription from RNA polymerase II promoter|activation of inositol anabolism by positive regulation of transcription from RNA polymerase II promoter|activation of inositol formation by positive regulation of transcription from RNA polymerase II promoter|positive regulation of inositol formation by positive regulation of transcription from RNA polymerase II promoter|up-regulation of inositol anabolism by positive regulation of transcription from RNA polymerase II promoter|upregulation of inositol formation by positive regulation of transcription from RNA polymerase II promoter|activation of myo-inositol biosynthesis by positive regulation of transcription from RNA polymerase II promoter|activation of inositol biosynthesis by positive regulation of transcription from RNA polymerase II promoter|upregulation of vitamin Bh biosynthesis by positive regulation of transcription from RNA polymerase II promoter|positive regulation of vitamin Bh biosynthesis by positive regulation of transcription from RNA polymerase II promoter|up-regulation of inositol formation by positive regulation of transcription from RNA polymerase II promoter|positive regulation of inositol synthesis by positive regulation of transcription from RNA polymerase II promoter|positive regulation of myo-inositol biosynthetic process by positive regulation of transcription from RNA polymerase II promoter|upregulation of inositol biosynthetic process by positive regulation of transcription from RNA polymerase II promoter|up regulation of myo-inositol biosynthetic process by positive regulation of transcription from RNA polymerase II promoter|activation of vitamin Bh biosynthetic process by positive regulation of transcription from RNA polymerase II promoter|upregulation of inositol biosynthesis by positive regulation of transcription from RNA polymerase II promoter					This term was obsoleted because it represents a GO-CAM model.		krc	2012-04-17T12:45:48Z		True			biological_process											owl:Class	
GO:0005957	biolink:NamedThing	obsolete debranching enzyme	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	debranching enzyme					This term was made obsolete because it is ambiguous (there are several debranching enzymes) and because it probably represents the glycogen debranching enzyme which is a single gene product and not a complex.	GO:0043033				True			cellular_component											owl:Class	
GO:0052208	biolink:NamedThing	obsolete modification of morphology or physiology of other organism via substance secreted by type IV secretion system involved in symbiotic interaction	OBSOLETE. The process in which an organism effects a change in the structure or function of a second organism, mediated by a substance secreted by a type IV secretion system in the first organism, where the two organisms are in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	modification of morphology or physiology of other organism via substance secreted by type IV secretion system during symbiotic interaction					This term was obsoleted because it conflated the process in which a gene product is involved with the secretion system by which it reaches its target.					True			biological_process											owl:Class	
GO:0030192	biolink:NamedThing	obsolete Hsp70/Hsc70 protein regulator activity	OBSOLETE. Modulates the activity of chaperones of the Hsp70/Hsc70 class.	tmpzr1t_l9r_go_relaxed.owl	Hsp70/Hsc70 protein regulator activity					This term was made obsolete because it refers to a non-existent molecular function term, 'Hsp70/Hsc70 protein activity'.	GO:0051787|GO:0006457|GO:0051082				True			molecular_function											owl:Class	
GO:1990802	biolink:NamedThing	obsolete protein phosphorylation involved in DNA double-strand break processing	OBSOLETE. Any protein phosphorylation that is required for DNA double-strand break processing.	tmpzr1t_l9r_go_relaxed.owl	protein amino acid phosphorylation involved in DNA double-strand break processing	https://github.com/geneontology/go-ontology/issues/14137				This term has been obsoleted because it represents a GO-CAM model.		rb	2015-07-16T20:43:39Z		True			biological_process											owl:Class	
GO:0007401	biolink:NamedThing	obsolete pan-neural process	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	pan-neural process					This term was made obsolete because its meaning is ambiguous.	GO:0050877|GO:0007399				True			biological_process											owl:Class	
GO:0007230	biolink:NamedThing	obsolete calcium-o-sensing receptor pathway	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	calcium-o-sensing receptor pathway					This term was made obsolete because it does not make sense.	GO:0019722				True			biological_process											owl:Class	
GO:0019443	biolink:NamedThing	obsolete tryptophan catabolic process, using tryptophanase	OBSOLETE. The chemical reactions and pathways resulting in the breakdown of tryptophan, catalyzed by the enzyme tryptophanase (EC:4.1.99.1).	tmpzr1t_l9r_go_relaxed.owl	tryptophan catabolic process, using tryptophanase|tryptophan breakdown, using tryptophanase|tryptophan degradation, using tryptophanase					This term was made obsolete because it refers to a one-step pathway.	GO:0009034|GO:0006569				True			biological_process											owl:Class	
GO:0033697	biolink:NamedThing	obsolete positive regulation of extent of heterochromatin assembly	OBSOLETE. Any process that increases the extent of heterochromatin formation; increases the size of a chromosomal region converted to heterochromatin.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of heterochromatin spreading|positive regulation of extent of heterochromatin formation	https://github.com/geneontology/go-ontology/issues/22028				This term has been obsoleted because there is no evidence it exists.	GO:0031507				True			biological_process											owl:Class	
GO:1904165	biolink:NamedThing	obsolete positive regulation of triglyceride homeostasis	OBSOLETE. Any process that activates or increases the frequency, rate or extent of triglyceride homeostasis.	tmpzr1t_l9r_go_relaxed.owl	upregulation of triacylglycerol homeostasis|upregulation of triglyceride homeostasis|up regulation of triacylglycerol homeostasis|activation of triglyceride homeostasis|up-regulation of triglyceride homeostasis|activation of triacylglycerol homeostasis|up regulation of triglyceride homeostasis|up-regulation of triacylglycerol homeostasis|positive regulation of triacylglycerol homeostasis					This term was obsoleted at the TermGenie Gatekeeper stage.		rph	2015-04-22T11:04:55Z		True			biological_process											owl:Class	
GO:0030601	biolink:NamedThing	obsolete aminopeptidase B activity	OBSOLETE. Catalysis of the release of N-terminal Arg and Lys from oligopeptides when P1' is not Pro. Also acts on arylamides of Arg and Lys.	tmpzr1t_l9r_go_relaxed.owl	arginyl aminopeptidase activity|L-arginine aminopeptidase activity|aminopeptidase B activity|Cl--activated arginine aminopeptidase activity|arylamidase II|cytosol aminopeptidase IV			GO:0004177		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0030364	biolink:NamedThing	obsolete cleavage and polyadenylylation specificity factor activity	OBSOLETE. A factor required in mRNA 3' end processing for both the cleavage and poly(A) addition reactions and, consistent with this function, recognizes AAUAAA, a signal also essential for both reactions.	tmpzr1t_l9r_go_relaxed.owl	cleavage and polyadenylation specificity factor activity|cleavage/polyadenylation specificity factor activity|cleavage and polyadenylylation specificity factor activity|CPSF			GO:0005847		This term was made obsolete because it describes a cellular component.	GO:0006379|GO:0006378				True			molecular_function											owl:Class	
GO:0072439	biolink:NamedThing	obsolete detection of stimulus involved in meiotic DNA replication checkpoint	OBSOLETE. The series of events in which information about whether DNA replication is complete is received and converted into a molecular signal, contributing to a meiotic DNA replication checkpoint.	tmpzr1t_l9r_go_relaxed.owl	meiotic DNA replication checkpoint sensor mechanism|sensing involved in meiotic DNA replication checkpoint|meiotic DNA replication checkpoint sensor process	https://github.com/geneontology/go-ontology/issues/20976				This term was obsoleted because it corresponds to a molecular function.		mah	2010-12-08T04:59:08Z		True			biological_process											owl:Class	
GO:0007579	biolink:NamedThing	obsolete senescence factor accumulation	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	senescence factor accumulation					This term was made obsolete because it does not represent a process.					True			biological_process											owl:Class	
GO:0052224	biolink:NamedThing	obsolete energy taxis in other organism involved in symbiotic interaction	OBSOLETE. The directed movement of a motile cell or organism within a second organism in response to physical parameters involved in energy generation, such as light, oxygen, and oxidizable substrates, where the two organisms are in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	energy taxis within other organism during symbiotic interaction|energy taxis in other organism during symbiotic interaction					This term was obsoleted because it represents both a process and a location.					True			biological_process											owl:Class	
GO:0005570	biolink:NamedThing	obsolete small nuclear RNA	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	small nuclear RNA					This term was made obsolete because it represents gene products.	GO:0017069|GO:0000375				True			molecular_function											owl:Class	
GO:0075064	biolink:NamedThing	obsolete negative regulation invasive hypha growth	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of symbiont invasive hypha formation within host. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of symbiont invasive hypha formation within host|negative regulation of symbiont invasive hypha formation in host	https://github.com/geneontology/go-ontology/issues/19013				This term was obsoleted because there is no evidence that this process exists.					True			biological_process											owl:Class	
GO:0075092	biolink:NamedThing	obsolete negative regulation by host of symbiont signal transduction mediated by G-protein alpha subunit	OBSOLETE. Any process in which the host organism stops, prevents, or reduces the frequency, rate or extent of the symbiont signal transduction mediated by G-protein alpha subunit. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl						The reason for obsoletion is that there is no evidence that the host can modulate or regulate a symbiont's signal transduction pathway.					True			biological_process											owl:Class	
GO:0005626	biolink:NamedThing	obsolete insoluble fraction	OBSOLETE. That fraction of cells, prepared by disruptive biochemical methods, that is not soluble in water.	tmpzr1t_l9r_go_relaxed.owl	particle-bound|insoluble fraction					This term was made obsolete because it refers to a cell fractionation experimental result and not a bona fide cellular component.	GO:0005575				True			cellular_component											owl:Class	
GO:1990214	biolink:NamedThing	obsolete negative regulation by symbiont of host protein levels	OBSOLETE. Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of protein levels in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it is a readout, and annotations should be made to more informative terms.		ml	2013-10-10T15:39:45Z		True			biological_process											owl:Class	
GO:0100004	biolink:NamedThing	obsolete positive regulation of peroxisome organization by transcription from RNA polymerase II promoter	OBSOLETE. Any transcription from RNA polymerase II promoter process that positively regulates peroxisome organization.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it represents a GO-CAM model.		cjm	2015-04-02T04:13:19Z		True			biological_process											owl:Class	
GO:0004251	biolink:NamedThing	obsolete X-Pro dipeptidase activity	OBSOLETE. Catalysis of the hydrolysis of Xaa-Pro dipeptides; also acts on aminoacyl-hydroxyproline analogs. No action on Pro-Pro.	tmpzr1t_l9r_go_relaxed.owl	gamma-peptidase activity|proline dipeptidase activity|imidodipeptidase activity|peptidase D|X-Pro dipeptidase activity|Xaa-Pro dipeptidase activity|prolidase activity				MetaCyc:3.4.13.9-RXN|EC:3.4.13.9	This term was made obsolete because it represents a gene product.	GO:0016805|GO:0008235				True			molecular_function											owl:Class	
GO:0030188	biolink:NamedThing	obsolete chaperone regulator activity	OBSOLETE. Modulates the activity of a molecular chaperone.	tmpzr1t_l9r_go_relaxed.owl	chaperone regulator activity					This term was made obsolete because it refers to a obsolete molecular function term, 'chaperone activity'.	GO:0051082|GO:0051787|GO:0006457				True			molecular_function											owl:Class	
GO:0044045	biolink:NamedThing	obsolete interaction with host via substance in symbiont cell outer membrane	OBSOLETE. An interaction with the host organism mediated by a substance in the symbiont cell outer membrane - a lipid bilayer that forms the outermost layer of the symbiont cell envelope. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl						The reason for obsoletion is that these terms conflate a process and the mechanism of secretion of the compound mediating the process.					True			biological_process											owl:Class	
GO:2000285	biolink:NamedThing	obsolete negative regulation of regulation of excitatory postsynaptic membrane potential	OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of regulation of excitatory postsynaptic membrane potential.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of regulation of excitatory postsynaptic membrane potential|negative regulation of EPSP			GO:0090394		This term was made obsolete because it makes no sense and was added in error.		vk	2010-12-12T03:27:21Z		True			biological_process											owl:Class	
GO:0005430	biolink:NamedThing	obsolete synaptic vesicle amine transmembrane transporter activity	OBSOLETE. Enables the transfer of amines across synaptic vesicle membranes.	tmpzr1t_l9r_go_relaxed.owl						The class was obsoleted because the cellular location of a function should not be part of the class label.	GO:0005275				True			molecular_function											owl:Class	
GO:0075336	biolink:NamedThing	obsolete negative regulation of symbiont adenylate cyclase-mediated signal transduction in response to host	OBSOLETE. Any process in which the symbiont organism stops, prevents, or reduces the frequency, rate or extent of its symbiont adenylate cyclase-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because there is no evidence that this process exists.					True			biological_process											owl:Class	
GO:0038074	biolink:NamedThing	obsolete MAP kinase phosphatase activity involved in regulation of conjugation with cellular fusion	OBSOLETE. Catalysis of the reaction: a phosphorylated MAP kinase + H2O = a MAP kinase + phosphate, where the MAP kinase (MAPK) is part of a MAPK signaling cascade that contributes to conjugation with cellular fusion.	tmpzr1t_l9r_go_relaxed.owl	MAPK phosphatase activity involved in regulation of conjugation with cellular fusion					This term has been obsoleted because it represents a GO-CAM model rather than a single GO term.		bf	2012-01-26T02:31:57Z		True			molecular_function											owl:Class	
GO:0004202	biolink:NamedThing	obsolete caspase-2 activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	caspase-2 activity			GO:0004197		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0004246	biolink:NamedThing	obsolete peptidyl-dipeptidase A activity	OBSOLETE. Catalysis of the release of a C-terminal dipeptide, Xaa-Xbb from oligopeptide-Xaa-Xbb, when Xaa is not Pro, and Xbb is neither Asp nor Glu. Converts angiotensin I to angiotensin II.	tmpzr1t_l9r_go_relaxed.owl	peptidyl dipeptidase I activity|peptidase P activity|carboxycathepsin activity|dipeptidyl carboxypeptidase I activity|DCP|ACE activity|peptidyl dipeptidase-4|PDH|angiotensin converting enzyme|peptidyl dipeptidase A|endothelial cell peptidyl dipeptidase activity|peptidyl dipeptide hydrolase activity|peptidyl-dipeptide hydrolase activity|peptidyl-dipeptidase A activity|dipeptide hydrolase|peptidyldipeptide hydrolase activity|angiotensin I-converting enzyme activity|kininase II activity				EC:3.4.15.1|MetaCyc:3.4.15.1-RXN	This term was made obsolete because it represents a gene product.	GO:0008237|GO:0008241				True			molecular_function											owl:Class	
GO:0009077	biolink:NamedThing	obsolete histidine family amino acid catabolic process	OBSOLETE. The chemical reactions and pathways resulting in the breakdown of amino acids of the histidine family.	tmpzr1t_l9r_go_relaxed.owl	histidine family amino acid catabolic process|histidine family amino acid breakdown|histidine family amino acid degradation|histidine family amino acid catabolism			GO:0006548		This term was made obsolete because it was an unnecessary grouping term, as histidine would be the only member of this family.					True			biological_process											owl:Class	
GO:0042096	biolink:NamedThing	obsolete alpha-beta T cell receptor activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	alpha-beta T cell receptor activity					This term was made obsolete because it describes a receptor type, and not an activity.	GO:0032395|GO:0032394|GO:0042605				True			molecular_function											owl:Class	
GO:0019942	biolink:NamedThing	obsolete NEDD8 class-dependent protein catabolic process	OBSOLETE. The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by covalent attachment of the ubiquitin-like protein NEDD8 (RUB1) to the target protein.	tmpzr1t_l9r_go_relaxed.owl	NEDD8 class-dependent protein catabolism|RUB1-dependent protein degradation|NEDD8 class-dependent protein degradation|RUB1-dependent protein catabolism|NEDD8 class-dependent protein catabolic process|RUB1-dependent protein catabolic process|NEDD8 class-dependent protein breakdown					This term was made obsolete because NEDD8-class tags do not target proteins for proteolytic destruction.	GO:0045116				True			biological_process											owl:Class	
GO:0090621	biolink:NamedThing	obsolete APC-fizzy-related complex	OBSOLETE. An anaphase promoting complex bound to the fizzy-related family APC activator FZR1/Cdh1/Srw1 that regulates mitotic exit by activating the APC/C to target mitotic cyclins for destruction during anaphase and telophase. Is also active during G1.	tmpzr1t_l9r_go_relaxed.owl	APC-Hct1/Cdh1 complex|APC-Srw1 complex					This term was made obsolete because it is too fine-grained for GO.	GO:0005680	tb	2014-12-17T17:01:38Z		True			cellular_component											owl:Class	
GO:0004626	biolink:NamedThing	obsolete cytosolic phospholipase A2 activity	OBSOLETE. Catalysis of the reaction: phosphatidylcholine + H2O = 1-acylglycerophosphocholine + a fatty acid anion.	tmpzr1t_l9r_go_relaxed.owl	cytosolic phospholipase A2 activity					This term was made obsolete because it represents component and function information.	GO:0004623|GO:0005829				True			molecular_function											owl:Class	
GO:0005505	biolink:NamedThing	obsolete heavy metal binding	OBSOLETE. Interacting selectively with a heavy metal, a metal that can form a coordination bond with a protein, as opposed to an alkali or alkaline-earth metal that can only form an ionic bond; this definition includes the following biologically relevant heavy metals: Cd, Co, Cu, Fe, Hg, Mn, Mo, Ni, V, W, Zn.	tmpzr1t_l9r_go_relaxed.owl	heavy metal binding					This term was made obsolete because 'heavy metal' is an ambiguous grouping term which has no set meaning (see Pure Appl. Chem. Vol. 74, No. 5, pp. 793-807, 2002, for more information).	GO:0046872				True			molecular_function											owl:Class	
GO:0052233	biolink:NamedThing	obsolete positive aerotaxis in other organism involved in symbiotic interaction	OBSOLETE. The directed movement of a motile cell or organism towards a higher concentration of environmental oxygen within a second organism, where the two organisms are in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	positive aerotaxis in other organism during symbiotic interaction|positive aerotaxis within other organism during symbiotic interaction	https://github.com/geneontology/go-ontology/issues/18819				This term was obsoleted because it represents both a process and a location.					True			biological_process											owl:Class	
GO:1905713	biolink:NamedThing	obsolete mitochondrial calcium uptake involved in regulation of presynaptic cytosolic calcium ion concentration	OBSOLETE. Any mitochondrial calcium uptake that is involved in regulation of presynaptic cytosolic calcium ion concentration.	tmpzr1t_l9r_go_relaxed.owl	calcium ion transmembrane import into mitochondrion involved in regulation of presynaptic cytosolic calcium ion concentration|mitochondrial calcium uptake involved in regulation of presynaptic cytosolic calcium levels|calcium ion transmembrane import into mitochondrion involved in regulation of presynaptic cytosolic calcium levels					This term was obsoleted at the TermGenie Gatekeeper stage.		dos	2016-11-23T15:55:53Z		True			biological_process											owl:Class	
GO:1902717	biolink:NamedThing	obsolete sequestering of iron ion	OBSOLETE. Any process that modulates the frequency, rate or extent of sequestering of iron ion.	tmpzr1t_l9r_go_relaxed.owl	sequestering of iron ion					This term was obsoleted at the TermGenie Gatekeeper stage.		mr	2014-02-24T16:08:43Z		True			biological_process											owl:Class	
GO:1905196	biolink:NamedThing	obsolete positive regulation of ATPase activity, uncoupled	OBSOLETE. Any process that activates or increases the frequency, rate or extent of ATPase activity, uncoupled.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of adenylpyrophosphatase activity|activation of adenylpyrophosphatase activity|upregulation of ATPase activity, uncoupled|up regulation of ATPase activity, uncoupled|activation of ATPase activity, uncoupled|upregulation of adenylpyrophosphatase activity|up-regulation of adenylpyrophosphatase activity|up regulation of adenylpyrophosphatase activity|up-regulation of ATPase activity, uncoupled					The reason for obsoletion is that the there is no convincing example of a protein with this function.		al	2016-05-12T08:01:28Z		True			biological_process											owl:Class	
GO:0003807	biolink:NamedThing	obsolete plasma kallikrein activity	OBSOLETE. Catalysis of the selective cleavage of Arg-Xaa and Lys-Xaa bonds, including Lys-Arg and Arg-Ser bonds in (human) kininogen to release bradykinin.	tmpzr1t_l9r_go_relaxed.owl	dilminal D|glumorin|kallikrein|kallikrein II|panceatic kallikrein|depot-padutin|kininogenin activity|kininogenase|padutin|plasma kallikrein activity|urinary kallikrein|kallikrein I|callicrein|kallidinogenase|onokrein P|serum kallikrein activity|urokallikrein|padreatin			GO:0004252		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0000201	biolink:NamedThing	obsolete MAPK import into nucleus involved in cell wall organization or biogenesis	OBSOLETE. The directed movement of a MAP kinase to the nucleus that occurs in the context of cell wall organization or biogenesis.	tmpzr1t_l9r_go_relaxed.owl	cell wall biogenesis, MAPK import into nucleus|nuclear translocation of MAPK involved in cell wall integrity|cell wall biogenesis, nuclear translocation of MAPK|MAPK import into nucleus involved in cell wall integrity|nuclear translocation of MAPK involved in cell wall biogenesis|MAPK import into nucleus involved in cell wall biogenesis					The reason for obsoletion is that this term represents a GO-CAM model.	GO:0006606				True			biological_process											owl:Class	
GO:0075172	biolink:NamedThing	obsolete positive regulation of MAP kinase-mediated signal transduction in response to host	OBSOLETE. Any process in which the symbiont organism activates, maintains or increases the frequency, rate or extent of its MAP kinase-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of symbiont MAP kinase-mediated signal transduction in response to host					This term was obsoleted because there is no evidence that this process exists.					True			biological_process											owl:Class	
GO:0019066	biolink:NamedThing	obsolete translocation of virus into host cell	OBSOLETE. The translocation of an entire virus particle across the host cell plasma membrane.	tmpzr1t_l9r_go_relaxed.owl	translocation of virus into host cell|viral translocation			GO:0046718		This term was made obsolete because it is ambiguous, and more specific terms have been created.					True			biological_process											owl:Class	
GO:0090236	biolink:NamedThing	obsolete regulation of transcription from RNA polymerase II promoter involved in somitogenesis	OBSOLETE. Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the formation of mesodermal clusters that are arranged segmentally along the anterior posterior axis of an embryo.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it represents a GO-CAM model.	GO:0001756|GO:0006357	tb	2010-01-20T11:12:29Z		True			biological_process											owl:Class	
GO:0052180	biolink:NamedThing	obsolete negative regulation of peptidase activity in other organism involved in symbiotic interaction	OBSOLETE. Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of protease activity, the catalysis of the hydrolysis of peptide bonds in a protein, in a second organism, where the two organisms are in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	downregulation of protease activity in other organism during symbiotic interaction|negative regulation of protease activity in other organism during symbiotic interaction|down-regulation of protease activity in other organism during symbiotic interaction|inhibition of protease activity in other organism during symbiotic interaction|down regulation of protease activity in other organism during symbiotic interaction	https://github.com/geneontology/go-ontology/issues/21740				This term was obsoleted because it represents a molecular function.					True			biological_process											owl:Class	
GO:0000990	biolink:NamedThing	obsolete transcription factor activity, core RNA polymerase binding	OBSOLETE. Binding to an RNA polymerase in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well.	tmpzr1t_l9r_go_relaxed.owl	core RNA polymerase binding transcription factor activity	https://github.com/geneontology/go-ontology/issues/16053				The reason for obsoletion is that this concept is partly covered by other concepts in the ontology and usage has been inconsistent.	GO:0140110|GO:0043175	krc	2010-08-10T05:01:03Z		True			molecular_function											owl:Class	
GO:0090286	biolink:NamedThing	obsolete cytoskeletal anchoring at nuclear membrane	OBSOLETE. The process in which cytoskeletal filaments are directly or indirectly linked to the nuclear membrane.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/18283				This term was obsoleted because it represented a molecular function.	GO:0140444	tb	2010-02-18T02:56:26Z		True			biological_process											owl:Class	
GO:0044408	biolink:NamedThing	obsolete growth or development of symbiont on or near host	OBSOLETE. Any process in which the symbiont regulates the increase in its size or mass, or its progression from an initial condition to a later condition, within the cells or tissues of the host organism.	tmpzr1t_l9r_go_relaxed.owl	growth or development of symbiont on or near host|growth or development of organism on or near host surface										True			biological_process											owl:Class	
GO:0007106	biolink:NamedThing	obsolete cytokinesis, protein recruitment	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	cytokinesis, protein recruitment					This term was made obsolete because it was not defined.					True			biological_process											owl:Class	
GO:1990645	biolink:NamedThing	obsolete phosphorylase dephosphorylation	OBSOLETE. The modification of phosphorylases by removal of phosphate groups.	tmpzr1t_l9r_go_relaxed.owl	phosphorylase dephosphorylation					This term was obsoleted at the TermGenie Gatekeeper stage.		sl	2015-02-18T16:39:50Z		True			biological_process											owl:Class	
GO:0018332	biolink:NamedThing	obsolete enzyme active site formation via O-(phospho-5'-adenosine)-L-threonine	OBSOLETE. The transient adenylylation of threonine to form N6-(phospho-5'-adenosine)-L-threonine, found in the active site of bovine phosphodiesterase I.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/15594			RESID:AA0267	This term was obsoleted because it represents a reaction intermediate, not a biological process, see PMID:19039103 and PMID:19503829.					True			biological_process											owl:Class	
GO:0090046	biolink:NamedThing	obsolete regulation of transcription regulator activity	OBSOLETE. Any process that modulates the frequency, rate or extent of transcription regulator activity, any molecular function that plays a role in regulating transcription; may bind a promoter or enhancer DNA sequence or interact with a DNA-binding transcription factor.	tmpzr1t_l9r_go_relaxed.owl	regulation of transcription regulator activity					At the time of obsoletion, under "regulation of molecular function", a term exists for "regulation of sequence-specific DNA-binding transcription factor activity" and the positive and negative child terms, but no more detailed terms exist. In reannotating, please consider if the paper would support annotation to a regulation term for a specific RNA polymerase. Also consider if what you need would be regulation of protein binding transcription factor activity or any of its child terms instead. If so, please consider making a SF item regarding creation of such a term.		tb	2009-08-07T10:19:57Z		True			biological_process											owl:Class	
GO:0052182	biolink:NamedThing	obsolete modification by host of symbiont morphology or physiology via secreted substance	OBSOLETE. The process in which an organism effects a change in the structure or function of a symbiont organism, mediated by a substance secreted by one of the organisms. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it conflated the process in which a gene product is involved with the secretion system by which it reaches its target.					True			biological_process											owl:Class	
GO:0051074	biolink:NamedThing	obsolete protein tetramerization activity	OBSOLETE. The formation of a protein tetramer, a macromolecular structure consisting of four noncovalently associated identical or nonidentical subunits.	tmpzr1t_l9r_go_relaxed.owl	protein tetramerization activity			GO:0051262		This term was made obsolete because it represents a process.					True			molecular_function											owl:Class	
GO:0046018	biolink:NamedThing	obsolete positive regulation of transcription from RNA polymerase I promoter during mitotic cell cycle	OBSOLETE. Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase I promoter that occurs during the mitotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl	activation of transcription from RNA polymerase I promoter during mitosis|upregulation of transcription from RNA polymerase I promoter during mitosis|positive regulation of transcription from Pol I promoter during mitosis|stimulation of transcription from RNA polymerase I promoter during mitosis|mitotic activation of transcription from Pol I promoter|up-regulation of transcription from RNA polymerase I promoter during mitosis|positive regulation of transcription from RNA polymerase I promoter, mitotic|up regulation of transcription from RNA polymerase I promoter during mitosis	https://github.com/geneontology/go-ontology/issues/14896				The reason for obsoletion is that 'during' should be captured using an annotation extension.	GO:0044772|GO:0045943				True			biological_process											owl:Class	
GO:0004086	biolink:NamedThing	obsolete carbamoyl-phosphate synthase activity	OBSOLETE. Catalysis of a reaction that results in the formation of carbamoyl phosphate.	tmpzr1t_l9r_go_relaxed.owl	carbamoyl phosphate synthase activity|carbamoyl-phosphate synthase activity					This term was made obsolete because it is a grouping term based on name, rather than on function.	GO:0004087|GO:0004088				True			molecular_function											owl:Class	
GO:0005311	biolink:NamedThing	obsolete sodium:dicarboxylate/tricarboxylate symporter activity	OBSOLETE. Catalysis of the reaction: (dicarboxylate or tricarboxylate)(out) + Na+(out) = (dicarboxylate or tricarboxylate)(in) + Na+(in).	tmpzr1t_l9r_go_relaxed.owl	sodium:dicarboxylate/tricarboxylate symporter activity|sodium:dicarboxylate/tricarboxylate cotransporter activity					This term was made obsolete because it represents a multifunctional gene product.	GO:0005310|GO:0005343|GO:0015142				True			molecular_function											owl:Class	
GO:0100031	biolink:NamedThing	obsolete regulation of histone methylation by transcription from RNA polymerase II promoter	OBSOLETE. Any transcription from RNA polymerase II promoter process that regulates histone methylation.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it describes a process that does not exist.		cjm	2015-04-02T04:13:19Z		True			biological_process											owl:Class	
GO:0044120	biolink:NamedThing	obsolete development of symbiont in host vacuole	OBSOLETE. The progression of the symbiont from an initial condition to a later condition, occurring in a host vacuole. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	development of symbiont in host organelle	https://github.com/geneontology/go-ontology/issues/20305				This term was obsoleted because it represents both a process and a location.		jl	2009-07-30T03:59:54Z		True			biological_process											owl:Class	
GO:0003694	biolink:NamedThing	obsolete plasmid binding	OBSOLETE. Interacting selectively with a plasmid, an extrachromosomal genetic element usually characterized as a covalently continuous double stranded DNA molecule found in bacteria and some other microorganisms.	tmpzr1t_l9r_go_relaxed.owl	plasmid-associated protein|plasmid binding					This term was made obsolete because it refers to component information.	GO:0005727|GO:0003677				True			molecular_function											owl:Class	
GO:0003686	biolink:NamedThing	obsolete DNA repair enzyme	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	DNA repair enzyme					This term was made obsolete because it includes a process term.	GO:0003684				True			molecular_function											owl:Class	
GO:0019831	biolink:NamedThing	obsolete chromate sensitivity/resistance	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	chromate sensitivity/resistance			GO:0046687		This term was made obsolete because 'sensitivity/resistance' implies a phenotype rather than a biological process.					True			biological_process											owl:Class	
GO:0035959	biolink:NamedThing	obsolete positive regulation of glyoxylate cycle by positive regulation of transcription from RNA polymerase II promoter	OBSOLETE. Any process that activates or increases the frequency, rate or extent of the glyoxylate cycle by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of glyoxylate bypass by upregulation of transcription from RNA polymerase II promoter|positive regulation of glyoxylate cycle by up-regulation of transcription from RNA polymerase II promoter|positive regulation of glyoxylate cycle by positive regulation of transcription from Pol II promoter|positive regulation of glyoxylate cycle by upregulation of transcription from RNA polymerase II promoter|positive regulation of glyoxylate cycle by activation of transcription from RNA polymerase II promoter|positive regulation of glyoxylate cycle by stimulation of transcription from RNA polymerase II promoter|positive regulation of glyoxylate bypass by positive regulation of transcription from RNA polymerase II promoter|positive regulation of glyoxylate bypass by up regulation of transcription from RNA polymerase II promoter|positive regulation of glyoxylate cycle by up regulation of transcription from RNA polymerase II promoter|positive regulation of glyoxylate bypass by up-regulation of transcription from RNA polymerase II promoter|positive regulation of glyoxylate bypass by positive regulation of transcription from Pol II promoter					This term was obsoleted because it represents a GO-CAM model.		bf			True			biological_process											owl:Class	
GO:1901171	biolink:NamedThing	obsolete naphthalene biosynthetic process	OBSOLETE. The chemical reactions and pathways resulting in the formation of naphthalene.	tmpzr1t_l9r_go_relaxed.owl	naphthalene formation|naphthalene biosynthesis|naphthalene anabolism|naphthalene synthesis	https://github.com/geneontology/go-ontology/issues/20974				This term was obsoleted because there is no evidence that this process exists.		yaf	2012-07-19T09:34:11Z		True			biological_process											owl:Class	
GO:0045042	biolink:NamedThing	obsolete protein import into mitochondrial intermembrane space, conservative	OBSOLETE. The conservative import of proteins into the mitochondrial intermembrane space. The entire protein enters the matrix, and then the second targeting sequence directs the protein, presumably bound to a matrix protein, across the inner membrane to the intermembrane space.	tmpzr1t_l9r_go_relaxed.owl	conservative protein transport into mitochondrial intermembrane space|protein import into mitochondrial IMS, conservative|protein transport into mitochondrial IMS, conservative|conservative mitochondrial intermembrane space protein import|protein transport into mitochondrial intermembrane space, conservative|conservative mitochondrial IMS protein import|protein import into mitochondrial intermembrane space, conservative|conservative protein transport into mitochondrial IMS					This term was made obsolete because there is no 'conservative' process of protein import into the mitochondrial intermembrane space that is distinct from the more general parent; furthermore, 'conservative' is used in the literature to describe a pathway of import into the inner membrane rather than into the intermembrane space.	GO:0045039|GO:0045041				True			biological_process											owl:Class	
GO:0009919	biolink:NamedThing	obsolete cytokinesis (sensu Viridiplantae)	OBSOLETE. The division of a cell into two daughter cells with cell walls.	tmpzr1t_l9r_go_relaxed.owl	cytokinesis (sensu Viridiplantae)					This term was made obsolete because its meaning was changed significantly.	GO:0000911				True			biological_process											owl:Class	
GO:0016484	biolink:NamedThing	obsolete proprotein convertase 2 activator activity	OBSOLETE. Required for the maturation and activation of proprotein convertase 2.	tmpzr1t_l9r_go_relaxed.owl	proprotein convertase 2 activator activity					This term was made obsolete because it represents a regulator of an obsolete molecular function.	GO:0016504				True			molecular_function											owl:Class	
GO:2000500	biolink:NamedThing	obsolete positive regulation of induction of apoptosis in response to chemical stimulus	OBSOLETE. Any process that activates or increases the frequency, rate or extent of induction of apoptosis in response to chemical stimulus.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of induction of apoptosis in response to chemical stimulus|positive regulation of induction of apoptosis in response to chemical substance					This term was made obsolete because it is ill-defined.		yaf	2011-03-18T02:36:22Z		True			biological_process											owl:Class	
GO:0015406	biolink:NamedThing	obsolete ABC-type uptake permease activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	ABC-type uptake permease activity					This term was made obsolete because ABC transporters are a protein family rather than a functional grouping.	GO:0043190|GO:0042626				True			molecular_function											owl:Class	
GOREL:0000040	biolink:NamedThing	results_in		tmpzr1t_l9r_go_relaxed.owl					GOREL:0000040	This relation is currently used to connect two regulation processes p1 and p2, such that if r1 regulates p1 and r2 regulates p2, and r1 results_in r2 then the regulation of p1 is required for the regulation of p2. For an example of use, see GO:0035958 'regulation of glyoxylate cycle by regulation of transcription from RNA polymerase II promoter'. Note that a precise definition of this relation is under discussion. After it has been formalized it will be added to RO, where it will have a RO ID. Note that the existing identifier and label are subject to change.		cjm	2012-03-14T10:35:44Z					external									results_in			
GO:0003821	biolink:NamedThing	obsolete class II major histocompatibility complex antigen	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	class II major histocompatibility complex antigen					This term was made obsolete because it represents a gene product, and because describing something as an 'antigen' means that an organism can produce antibodies to it, which says nothing about the gene product activity.	GO:0042613				True			molecular_function											owl:Class	
GO:0000216	biolink:NamedThing	obsolete M/G1 transition of mitotic cell cycle	OBSOLETE. Progression from M phase to G1 phase of the mitotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl	M/G1 transition of mitotic cell cycle					This term was made obsolete because it does not refer to a real biological process.					True			biological_process											owl:Class	
GO:0031557	biolink:NamedThing	obsolete induction of programmed cell death in response to chemical stimulus	OBSOLETE. A process which directly activates any of the steps required for programmed cell death as a result of a chemical stimulus.	tmpzr1t_l9r_go_relaxed.owl	induction of programmed cell death in response to chemical stimulus|induction of programmed cell death in response to chemical substance					This term was made obsolete because it is now superseded by better defined and more specific terms under the node of GO:0012501 programmed cell death.					True			biological_process											owl:Class	
GO:0051857	biolink:NamedThing	obsolete growth or development of organism on or near symbiont surface	OBSOLETE. The increase in size or mass of an organism, or the progression of an organism from an initial condition to a later condition, occurring on or near the exterior of its symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	growth or development of organism during interaction with symbiont|growth or development of organism on or near symbiont surface						GO:0032502				True			biological_process											owl:Class	
GO:1900478	biolink:NamedThing	obsolete positive regulation of sulfate assimilation by positive regulation of transcription from RNA polymerase II promoter	OBSOLETE. Any process that activates or increases the frequency, rate or extent of sulfate assimilation by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of sulphate assimilation, phosphoadenylyl sulphate reduction by an oxidoreductase, acting on sulphur group of donors, NAD or NADP as acceptor by positive regulation of transcription from RNA polymerase II promoter|activation of sulfate assimilation by positive regulation of transcription from RNA polymerase II promoter|activation of sulphate assimilation by positive regulation of transcription from RNA polymerase II promoter|up regulation of sulfate assimilation by positive regulation of transcription from RNA polymerase II promoter|up regulation of sulfate assimilation, phosphoadenylyl sulfate reduction by an oxidoreductase, acting on sulfur group of donors, NAD or NADP as acceptor by positive regulation of transcription from RNA polymerase II promoter|upregulation of sulfate assimilation by positive regulation of transcription from RNA polymerase II promoter|up-regulation of sulfate assimilation by positive regulation of transcription from RNA polymerase II promoter|up regulation of sulphate assimilation, phosphoadenylyl sulphate reduction by an oxidoreductase, acting on sulphur group of donors, NAD or NADP as acceptor by positive regulation of transcription from RNA polymerase II promoter|up-regulation of sulphate assimilation by positive regulation of transcription from RNA polymerase II promoter|up-regulation of sulfate assimilation, phosphoadenylyl sulfate reduction by an oxidoreductase, acting on sulfur group of donors, NAD or NADP as acceptor by positive regulation of transcription from RNA polymerase II promoter|positive regulation of sulfate assimilation, phosphoadenylyl sulfate reduction by an oxidoreductase, acting on sulfur group of donors, NAD or NADP as acceptor by positive regulation of transcription from RNA polymerase II promoter|activation of sulphate assimilation, phosphoadenylyl sulphate reduction by an oxidoreductase, acting on sulphur group of donors, NAD or NADP as acceptor by positive regulation of transcription from RNA polymerase II promoter|upregulation of sulphate assimilation by positive regulation of transcription from RNA polymerase II promoter|upregulation of sulphate assimilation, phosphoadenylyl sulphate reduction by an oxidoreductase, acting on sulphur group of donors, NAD or NADP as acceptor by positive regulation of transcription from RNA polymerase II promoter|positive regulation of sulphate assimilation, phosphoadenylyl sulphate reduction by an oxidoreductase, acting on sulphur group of donors, NAD or NADP as acceptor by positive regulation of transcription from RNA polymerase II promoter|positive regulation of sulphate assimilation by positive regulation of transcription from RNA polymerase II promoter|activation of sulfate assimilation, phosphoadenylyl sulfate reduction by an oxidoreductase, acting on sulfur group of donors, NAD or NADP as acceptor by positive regulation of transcription from RNA polymerase II promoter|upregulation of sulfate assimilation, phosphoadenylyl sulfate reduction by an oxidoreductase, acting on sulfur group of donors, NAD or NADP as acceptor by positive regulation of transcription from RNA polymerase II promoter|up regulation of sulphate assimilation by positive regulation of transcription from RNA polymerase II promoter					This term was obsoleted because it represents a GO-CAM model.		dgf	2012-05-01T09:08:04Z		True			biological_process											owl:Class	
GO:0046229	biolink:NamedThing	obsolete 2-aminobenzenesulfonate biosynthetic process	OBSOLETE. The chemical reactions and pathways resulting in the formation of 2-aminobenzenesulfonate, an aromatic sulfonate used in organic synthesis and in the manufacture of various dyes and medicines.	tmpzr1t_l9r_go_relaxed.owl	2-aminobenzenesulfonate synthesis|2-aminobenzenesulfonate biosynthesis|2-aminobenzenesulfonate formation|2-aminobenzenesulphonate biosynthesis|2-aminobenzenesulfonate anabolism|2-aminobenzenesulphonate biosynthetic process|2-aminobenzenesulfonate biosynthetic process			GO:0018868		This term was made obsolete because 2-aminobenzenesulfonate is not synthesized by living organisms, and GO does not cover non-biological processes.					True			biological_process											owl:Class	
GO:0000367	biolink:NamedThing	obsolete second U12-type spliceosomal transesterification activity	OBSOLETE. Catalysis of the second transesterification reaction of U12-type spliceosomal mRNA splicing. Ligation of the two exons occurs via a transesterification reaction where the free 3'-hydroxyl group of the 5' exon is the nucleophile attacking the 3' splice site. Non-expressed sequences are now detached from the exons. In cis splicing, the intron is in a lariat structure. The catalytic site is thought to be formed by U6 and/or U2 snRNAs and/or associated proteins.	tmpzr1t_l9r_go_relaxed.owl	second U12-type spliceosomal transesterification activity|3'-splice site cleavage, exon ligation			GO:0000386		This term was made obsolete because the activities used in the U2- and U12-type complexes are the same. The cellular component ontology should (and does) represent the two different complexes, but the molecular function ontology should not.					True			molecular_function											owl:Class	
GO:0005190	biolink:NamedThing	obsolete seminal fluid protein	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	seminal fluid protein					This term was made obsolete because it describes presence in body fluids rather than an activity.					True			molecular_function											owl:Class	
GO:1901312	biolink:NamedThing	obsolete negative regulation of gene expression involved in extracellular matrix organization	OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of gene expression involved in extracellular matrix organization.	tmpzr1t_l9r_go_relaxed.owl	down regulation of expression of extracellular matrix proteins|downregulation of extracellular matrix protein production|down regulation of extracellular matrix protein production|inhibition of gene expression involved in extracellular matrix organization|inhibition of extracellular matrix protein production|down-regulation of extracellular matrix protein production|down regulation of gene expression involved in extracellular matrix organization|downregulation of expression of extracellular matrix proteins|down-regulation of expression of extracellular matrix proteins|inhibition of expression of extracellular matrix proteins|down-regulation of gene expression involved in extracellular matrix organization|negative regulation of expression of extracellular matrix proteins|downregulation of gene expression involved in extracellular matrix organization|negative regulation of extracellular matrix protein production					This term was made obsolete is that in these terms the 'involved in' process is not truly involved_in (i.e. part_of) the process but instead is causally upstream of it. We advise replacing annotations to these terms with annotations + extensions using the causally_upstream_of relation e.g. P1234 regulation of gene expression [causally_upstream_of] extracellular matrix organization.	GO:0010629	vk	2012-08-22T09:18:35Z		True			biological_process											owl:Class	
GO:0010153	biolink:NamedThing	obsolete polar cell elongation	OBSOLETE. Cell expansion that results in an increase in cell size along the axis of an organ in a polarized fashion.	tmpzr1t_l9r_go_relaxed.owl	polar cell elongation|polarity-dependent cell elongation					This term was made obsolete because it did not represent a process discrete from its sibling terms.	GO:0042815|GO:0042814				True			biological_process											owl:Class	
GO:0052054	biolink:NamedThing	obsolete negative regulation by symbiont of host peptidase activity	OBSOLETE. Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of host protease activity, the catalysis of the hydrolysis of peptide bonds in a protein. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	down regulation by symbiont of host protease activity|negative regulation by symbiont of host protease activity|down-regulation by symbiont of host protease activity|inhibition by symbiont of host protease activity|downregulation by symbiont of host protease activity|inhibition of host protease activity	https://github.com/geneontology/go-ontology/issues/21740				This term was obsoleted because it represents a molecular function.					True			biological_process											owl:Class	
GO:0031375	biolink:NamedThing	obsolete type II fatty acid synthase complex	OBSOLETE. A fatty acid synthase complex in which each polypeptide chain catalyzes a single activity.	tmpzr1t_l9r_go_relaxed.owl	type II fatty acid synthase|type II fatty acid synthase complex|type II FAS|type II FAS complex					Type II refers to the type of fatty acid synthase. Type I is in a complex, type II is not.					True			cellular_component											owl:Class	
GO:0052141	biolink:NamedThing	obsolete positive chemotaxis on or near host	OBSOLETE. The directed movement of a motile cell or organism towards a higher concentration of a specific chemical on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/18819				This term was obsoleted because it represents both a process and a location.					True			biological_process											owl:Class	
GO:1901372	biolink:NamedThing	obsolete trehalose biosynthetic process involved in ascospore formation	OBSOLETE. Any trehalose biosynthetic process that is involved in ascospore formation.	tmpzr1t_l9r_go_relaxed.owl	trehalose anabolism involved in ascospore biosynthesis|mycose biosynthesis involved in ascospore formation|trehalose synthesis involved in ascospore formation|trehalose formation involved in ascospore formation|mykose biosynthesis involved in ascospore formation|trehalose biosynthetic process involved in ascospore biosynthesis|trehalose biosynthesis involved in ascospore formation|mycose biosynthetic process involved in ascospore formation|mykose biosynthetic process involved in ascospore biosynthesis|mycose biosynthesis involved in ascospore biosynthesis|trehalose anabolism involved in ascospore formation|trehalose formation involved in ascospore biosynthesis|mycose biosynthetic process involved in ascospore biosynthesis|trehalose synthesis involved in ascospore biosynthesis|mykose biosynthetic process involved in ascospore formation|trehalose biosynthesis involved in ascospore biosynthesis|mykose biosynthesis involved in ascospore biosynthesis	https://github.com/geneontology/go-ontology/issues/18200				This term was obsoleted because it does not represent a specific pathway.		al	2012-09-25T11:06:48Z		True			biological_process											owl:Class	
GO:0016284	biolink:NamedThing	obsolete alanine aminopeptidase activity	OBSOLETE. Catalysis of the release of an N-terminal amino acid, preferentially alanine, from an oligopeptide or polypeptide.	tmpzr1t_l9r_go_relaxed.owl	alanine aminopeptidase activity				EC:3.4.11.-	This term was made obsolete because it represents a gene product, and the substrate specificity it refers to is not cleanly defined.	GO:0008235|GO:0004177				True			molecular_function											owl:Class	
GO:0018183	biolink:NamedThing	obsolete enzyme active site formation via S-selenyl-L-cysteine	OBSOLETE. The transient selenylation of peptidyl-cysteine to form S-selenyl-L-cysteine.	tmpzr1t_l9r_go_relaxed.owl	enzyme active site formation via S-selenyl-L-cysteine					This term was made obsolete because this structure does not exist.					True			biological_process											owl:Class	
GO:0034649	biolink:NamedThing	obsolete histone demethylase activity (H3-monomethyl-K4 specific)	OBSOLETE. Catalysis of the removal of a methyl group from monomethylated lysine at position 4 of the histone H3 protein.	tmpzr1t_l9r_go_relaxed.owl	histone demethylase activity (H3-K4-me1 specific)	https://github.com/geneontology/go-ontology/issues/21089				This term was obsoleted to align with RHEA and EC: this is a sub-reaction both in RHEA:60208 and EC:1.14.11.67.	GO:0034647|GO:0140682				True			molecular_function											owl:Class	
GO:0036208	biolink:NamedThing	obsolete negative regulation of histone gene expression	OBSOLETE. Any process that decreases the frequency, rate or extent of expression of a histone-encoding gene. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of expression of histone-encoding gene|downregulation of histone gene expression|down-regulation of histone gene expression|inhibition of histone gene expression	https://github.com/geneontology/go-ontology/issues/20209				This term was obsoleted because the gene product should be captured as an annotation extension using 'has input'.	GO:0000122	bf	2012-04-25T09:29:43Z		True			biological_process											owl:Class	
GO:0033665	biolink:NamedThing	obsolete regulation of growth or development of symbiont in host	OBSOLETE. Any process by which the symbiont regulates the increase in its size or mass, or its progression from an initial condition to a later condition, within the cells or tissues of the host organism. This may (but not necessarily) include a filamentous growth form, and also can include secretion of proteases and lipases to break down. The host is defined as the larger of the organisms involved in the symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	regulation of growth or development of symbiont within host|regulation of growth or development of symbiont in host|modulation of invasive growth|modulation of growth or development of organism within host|modulation of growth or development of symbiont within host					This term was made obsolete because it contained a conjunction (or).	GO:0044127				True			biological_process											owl:Class	
GO:0019562	biolink:NamedThing	obsolete L-phenylalanine catabolic process to phosphoenolpyruvate	OBSOLETE. The chemical reactions and pathways resulting in the breakdown of L-phenylalanine into other compounds, including phosphoenolpyruvate.	tmpzr1t_l9r_go_relaxed.owl	phenylalanine breakdown to phosphoenolpyruvate|phenylalanine degradation to phosphoenolpyruvate				MetaCyc:PHENYLALANINE-DEG1-PWY	The reason for obsoletion is that there is no evidence that this is a real process.					True			biological_process											owl:Class	
GO:0036083	biolink:NamedThing	obsolete positive regulation of unsaturated fatty acid biosynthetic process by positive regulation of transcription from RNA polymerase II promoter	OBSOLETE. Any process that activates or increases the frequency, rate or extent of unsaturated fatty acid biosynthetic process by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it represents a GO-CAM model.		bf	2011-12-20T04:52:36Z		True			biological_process											owl:Class	
GO:0008075	biolink:NamedThing	obsolete receptor guanylate cyclase activity	OBSOLETE. Catalysis of the reaction: GTP = 3',5'-cyclic GMP + diphosphate.	tmpzr1t_l9r_go_relaxed.owl	receptor guanylate cyclase activity					This term was made obsolete because it represents a class of gene products.	GO:0004383|GO:0038023				True			molecular_function											owl:Class	
GO:0006926	biolink:NamedThing	obsolete virus-infected cell apoptotic process	OBSOLETE. Any apoptotic process in a cell infected with a virus.	tmpzr1t_l9r_go_relaxed.owl	killing virus-infected cells|virus-infected cell apoptotic process|programmed cell death of virus-infected cells by apoptosis|virus-infected cell programmed cell death by apoptosis|virus-infected cell apoptosis|apoptosis of virus-infected cells|programmed cell death, virus-infected cells					This term was made obsolete because the meaning of the term is ambiguous, as it's possibly conflating at least two scenarios: 1) the organism apoptoses its own cell because it detects it is infected with a virus; 2) the virus induces apoptosis so the cell is lysed and the virus disseminated. Please consider using viral process terms to annotate viral proteins. As for the cellular apoptotic process, this likely occurs via the same mechanisms described by existing apoptotic process terms, so please consider using those to annotate cellular proteins.					True			biological_process											owl:Class	
GO:0016566	biolink:NamedThing	obsolete specific transcriptional repressor activity	OBSOLETE. Any activity that stops or downregulates transcription of specific genes or sets of genes.	tmpzr1t_l9r_go_relaxed.owl	specific transcriptional repressor activity					This term was obsoleted because "general/nonspecific/basal" transcription vs "specific" transcription were determined not to be separable, distinct process. Thus, terms trying to distinguish "general/nonspecific/basal" transcription from "specific" transcription were removed from both the Molecular Function and the Biological Process ontologies. In addition, this Molecular Function term was defined only in terms of the process it acts in and it does NOT convey any information about the molecular nature of the function or whether the function is based on binding DNA, on interacting with other proteins, or some other mechanism. To transfer all annotations without review, the BP term indicated is considered to be equivalent and thus the only appropriate destination for all annotations. To reannotate to a MF term, you will probably need to revisit the original literature or other primary data because this "MF" term was not defined in terms of mechanism of action and there are multiple possibilities in the revised MF structure. In reannotation, please also consider descendent terms of the suggested MF terms as a more specific term may be more appropriate than the MF terms indicated. Please be aware that you may wish to request a new term if the mechanism of action of your repressor is not yet represented or if you are annotating for an RNAP different than one for which there is a specific suggested term. Also note that if there is no information about how the gene product acts, it may be appropriate to annotate to the root term for molecular_function.	GO:0001227|GO:0045892|GO:0001217				True			molecular_function											owl:Class	
GO:0006292	biolink:NamedThing	obsolete pyrimidine-dimer repair, DNA damage recognition	OBSOLETE. The location of pyrimidine dimers by a large multienzyme complex that scans the DNA for distortions in the double helix caused by pyrimidine dimers.	tmpzr1t_l9r_go_relaxed.owl	pyrimidine-dimer repair, DNA damage recognition					This term was made obsolete because it is a substrate specific DNA repair process.	GO:0000715|GO:0000716				True			biological_process											owl:Class	
GO:1905549	biolink:NamedThing	obsolete positive regulation of subtelomeric heterochromatin assembly	OBSOLETE. Any process that activates or increases the frequency, rate or extent of subtelomeric heterochromatin assembly.	tmpzr1t_l9r_go_relaxed.owl	up regulation of telomeric heterochromatin formation|up-regulation of telomeric heterochromatin formation|positive regulation of telomeric heterochromatin assembly|activation of telomeric heterochromatin formation|positive regulation of telomeric heterochromatin formation|up-regulation of telomeric heterochromatin assembly|upregulation of telomeric heterochromatin formation|up regulation of telomeric heterochromatin assembly|upregulation of telomeric heterochromatin assembly|activation of telomeric heterochromatin assembly	https://github.com/geneontology/go-ontology/issues/22027|https://github.com/geneontology/go-ontology/issues/19188				This term was obsoleted because there is no evidence that chromatin silencing /heterochromatin assembly are directly regulated.		nc	2016-10-12T11:18:30Z		True			biological_process											owl:Class	
GO:0016910	biolink:NamedThing	obsolete SAP kinase 3 activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	SAP kinase 3 activity|SAPK3					This term was made obsolete because it describes a gene product.	GO:0004674|GO:0007254				True			molecular_function											owl:Class	
GO:0006100	biolink:NamedThing	obsolete tricarboxylic acid cycle intermediate metabolic process	OBSOLETE. The chemical reactions and pathways involving intermediates of the tricarboxylic acid cycle.	tmpzr1t_l9r_go_relaxed.owl	TCA intermediate metabolism|citric acid cycle intermediate metabolism|tricarboxylic acid cycle intermediate metabolic process|citric acid cycle intermediate metabolic process|Krebs cycle intermediate metabolism|Krebs cycle intermediate metabolic process|TCA intermediate metabolic process|tricarboxylic acid cycle intermediate metabolism					This term was made obsolete because it is a grouping term that is not useful, but has caused true path violations.	GO:0006108|GO:0006104|GO:0006103|GO:0006106|GO:0006101|GO:0006107|GO:0006099|GO:0006105				True			biological_process											owl:Class	
GO:0003103	biolink:NamedThing	obsolete positive regulation of diuresis	OBSOLETE. Any process that activates or increases the frequency, rate or extent of diuresis. Diuresis is the process of renal water excretion.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of diuresis					This term was made obsolete because its definition was inaccurate.	GO:0035810				True			biological_process											owl:Class	
GO:0033264	biolink:NamedThing	obsolete bontoxilysin activity	OBSOLETE. Catalysis of limited hydrolysis of proteins of the neuroexocytosis apparatus, synaptobrevins, SNAP25 or syntaxin. No detected action on small molecule substrates.	tmpzr1t_l9r_go_relaxed.owl	BoNT|bontoxilysin activity|botulinum neurotoxin activity			GO:0004222		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0005211	biolink:NamedThing	obsolete plasma glycoprotein	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	plasma glycoprotein					This term was made obsolete because it describes modification and presence in body fluids rather than an activity.					True			molecular_function											owl:Class	
GO:0015524	biolink:NamedThing	obsolete L-arabinose/beta-D-thiogalactopyranoside:hydrogen antiporter activity	OBSOLETE. Catalysis of the reaction: H+(out) + (L-arabinose or beta-D-thiogalactopyranoside)(in) = H+(in) + (L-arabinose or beta-D-thiogalactopyranoside)(out).	tmpzr1t_l9r_go_relaxed.owl	L-arabinose/beta-D-thiogalactopyranoside:proton antiporter activity|L-arabinose/beta-D-thiogalactopyranoside:hydrogen antiporter activity					This term was made obsolete because it represents a gene product rather than a single discrete molecular function.	GO:0015147|GO:0015299|GO:0051119				True			molecular_function											owl:Class	
GO:0018333	biolink:NamedThing	obsolete enzyme active site formation via O-phospho-L-threonine	OBSOLETE. The transient phosphorylation of peptidyl-threonine to form O-phospho-L-threonine.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/15594			RESID:AA0038	This term was obsoleted because it was created by error: tyrosine phosphorylation does not generate an active site.					True			biological_process											owl:Class	
GO:0045139	biolink:NamedThing	obsolete copper sensitivity/resistance	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	copper sensitivity/resistance			GO:0046688		This term was made obsolete because 'sensitivity/resistance' implies a phenotype rather than a biological process.					True			biological_process											owl:Class	
GO:1900538	biolink:NamedThing	obsolete positive regulation of glucose homeostasis	OBSOLETE. Any process that activates or increases the frequency, rate or extent of glucose homeostasis.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of glucose homeostasis|up regulation of glucose homeostasis|positive regulation of glucose homeostasis|activation of glucose homeostasis|upregulation of glucose homeostasis					This term was obsoleted at the TermGenie Gatekeeper stage.		hjd	2012-05-10T06:53:38Z		True			biological_process											owl:Class	
GO:0045562	biolink:NamedThing	obsolete regulation of TRAIL receptor 2 biosynthetic process	OBSOLETE. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of TRAIL (TNF-related apoptosis inducing ligand) receptor 2.	tmpzr1t_l9r_go_relaxed.owl	regulation of TRAIL receptor 2 biosynthesis|regulation of TRAIL receptor 2 synthesis|regulation of TRAIL receptor 2 anabolism|regulation of TRAIL receptor 2 formation	https://github.com/geneontology/go-ontology/issues/19900				The reason for obsoletion is that those represent specific gene products, and genes annotated to those terms should be annotated to 'regulation of gene expression' or 'regulation of transcription' or some signaling term.					True			biological_process											owl:Class	
GO:0004209	biolink:NamedThing	obsolete caspase-6 activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	caspase-6 activity			GO:0004197		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0016164	biolink:NamedThing	obsolete Mo-molybdopterin oxidoreductase activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	molybdopterin oxidoreductase activity|Mo-molybdopterin oxidoreductase activity			GO:0016491		This term was made obsolete because the differentia from the parent is a gene product feature (specifically, the presence of a molybdopterin cofactor in the protein). It has also never been defined.					True			molecular_function											owl:Class	
GO:0019893	biolink:NamedThing	obsolete DNA replication inhibitor	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	DNA replication inhibitor			GO:0008156		This term was made obsolete because it does not represent a true molecular function.					True			molecular_function											owl:Class	
GO:0005079	biolink:NamedThing	obsolete protein kinase A anchoring activity	OBSOLETE. Binds to protein kinase A and anchors it to a particular subcellular location.	tmpzr1t_l9r_go_relaxed.owl	AKAP activity|protein kinase A anchoring activity|A-kinase anchor protein activity					This term was made obsolete because it represents a combination of process and function information.	GO:0051018|GO:0008104				True			molecular_function											owl:Class	
GO:0016088	biolink:NamedThing	obsolete insulin	OBSOLETE. A polypeptide hormone that stimulates glucose uptake by muscle and adipose tissue, and promotes glycogenesis, lipogenesis and the synthesis of proteins and nucleic acids.	tmpzr1t_l9r_go_relaxed.owl	insulin					This term was made obsolete because it represents a gene product.	GO:0046326|GO:0045722|GO:0045935|GO:0045727|GO:0046889|GO:0005102				True			molecular_function											owl:Class	
GO:1900031	biolink:NamedThing	obsolete regulation of transcription from RNA polymerase II promoter involved in calcium-mediated signaling	OBSOLETE. Any regulation of transcription from RNA polymerase II promoter that is involved in calcium-mediated signaling.	tmpzr1t_l9r_go_relaxed.owl	regulation of gene-specific transcription from RNA polymerase II promoter of calcium ion signaling|regulation of transcription from Pol II promoter of calcium signalling|global transcription regulation from Pol II promoter of calcium-mediated signaling|global transcription regulation from Pol II promoter of calcium ion signaling|global transcription regulation from Pol II promoter of calcium-mediated signalling|regulation of transcription from Pol II promoter of calcium signaling|regulation of transcription from RNA polymerase II promoter of calcium signalling|regulation of gene-specific transcription from RNA polymerase II promoter of calcium signalling|regulation of transcription from Pol II promoter of calcium-mediated signaling|regulation of gene-specific transcription from RNA polymerase II promoter of calcium-mediated signaling|regulation of transcription from RNA polymerase II promoter, global of calcium signaling|regulation of transcription from RNA polymerase II promoter of calcium-mediated signalling|regulation of transcription from RNA polymerase II promoter of calcium-mediated signaling|regulation of transcription from RNA polymerase II promoter involved in calcium-mediated signaling|regulation of transcription from RNA polymerase II promoter, global of calcium-mediated signalling|regulation of transcription from RNA polymerase II promoter, global of calcium-mediated signaling|regulation of gene-specific transcription from RNA polymerase II promoter of calcium-mediated signalling|regulation of global transcription from Pol II promoter of calcium signaling|regulation of transcription from RNA polymerase II promoter, global of calcium signalling|regulation of transcription from Pol II promoter of calcium-mediated signalling|regulation of transcription from RNA polymerase II promoter, global of calcium ion signaling|regulation of global transcription from Pol II promoter of calcium ion signaling|global transcription regulation from Pol II promoter of calcium signaling|global transcription regulation from Pol II promoter of calcium signalling|regulation of transcription from RNA polymerase II promoter of calcium ion signaling|regulation of global transcription from Pol II promoter of calcium-mediated signaling|regulation of gene-specific transcription from RNA polymerase II promoter of calcium signaling|regulation of transcription from Pol II promoter of calcium ion signaling|regulation of global transcription from Pol II promoter of calcium signalling|regulation of transcription from RNA polymerase II promoter of calcium signaling|regulation of global transcription from Pol II promoter of calcium-mediated signalling						GO:0019722|GO:0006357	krc	2012-01-13T04:09:19Z		True			biological_process											owl:Class	
GO:0000072	biolink:NamedThing	obsolete M phase specific microtubule process	OBSOLETE. A microtubule-based process that occurs only during M phase of the cell cycle.	tmpzr1t_l9r_go_relaxed.owl	M-phase specific microtubule process|M phase specific microtubule process					This term was made obsolete because terms already exist for centrosome/spindle organization which would be more suitable for the existing annotations, and the phase could be captured as an annotation extension if necessary.	GO:0007017				True			biological_process											owl:Class	
GO:0009335	biolink:NamedThing	obsolete holo-[acyl-carrier protein] synthase complex	OBSOLETE. An enzyme complex that catalyzes the formation of holo-[acyl-carrier protein] from CoA and apo-[acyl-carrier protein].	tmpzr1t_l9r_go_relaxed.owl	holo-ACP synthase complex|holo-[acyl-carrier protein] synthase complex					This term was made obsolete because the catalytic activity resides in a single polypeptide rather than a complex, and the complex is represented by a different GO term.	GO:0005835				True			cellular_component											owl:Class	
GO:1903759	biolink:NamedThing	obsolete signal transduction involved in regulation of aerobic respiration	OBSOLETE. Any signal transduction that is involved in regulation of aerobic respiration.	tmpzr1t_l9r_go_relaxed.owl	signaling cascade involved in regulation of aerobic respiration|signalling cascade involved in regulation of aerobic respiration|signaling pathway involved in regulation of aerobic respiration|signalling pathway involved in regulation of aerobic respiration					The reason for obsoletion is that this represents a GO-CAM model.		al	2014-12-18T16:37:50Z		True			biological_process											owl:Class	
GO:0016252	biolink:NamedThing	obsolete nonspecific RNA polymerase II transcription factor activity	OBSOLETE. Any function that supports transcription of genes by RNA polymerase II, and is not specific to a particular gene or gene set.	tmpzr1t_l9r_go_relaxed.owl	nonspecific RNA polymerase II transcription factor activity					This term was obsoleted because "general/nonspecific/basal" transcription vs "specific" transcription were determined not to be separable, distinct process. Thus, terms trying to distinguish "general/nonspecific/basal" transcription from "specific" transcription were removed from both the Molecular Function and the Biological Process ontologies. In addition, this Molecular Function term was defined only in terms of the process it acts in and it does NOT convey any information about the molecular nature of the function or whether the function is based on binding DNA, on interacting with other proteins, or some other mechanism. To transfer all annotations without review, the BP term indicated is considered to be equivalent and thus the only appropriate destination for all annotations. To reannotate to a MF term, you will probably need to revisit the original literature or other primary data because this "MF" term was not defined in terms of mechanism of action and there are multiple possibilities in the revised MF structure. In reannotation, please also consider descendent terms of the suggested MF terms as a more specific term may be more appropriate than the MF terms indicated. Also note that if there is no information about how the gene product acts, it may be appropriate to annotate to the root term for molecular_function.	GO:0016251|GO:0006366				True			molecular_function											owl:Class	
GO:0052426	biolink:NamedThing	obsolete modification by organism of symbiont morphology or physiology via substance secreted by type IV secretion system	OBSOLETE. The process by which an organism effects a change in the structure or function of its symbiont organism, mediated by a substance secreted by a type IV secretion system in the organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	modification by organism of symbiont morphology or physiology via substance secreted by type IV secretion system					This term was made obsolete because it does not represent a real biological process.					True			biological_process											owl:Class	
GO:0016351	biolink:NamedThing	obsolete drug susceptibility/resistance	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	drug susceptibility/resistance			GO:0009410		This term was made obsolete because 'susceptibility/resistance' implies a phenotype rather than a biological process.					True			biological_process											owl:Class	
GO:0008370	biolink:NamedThing	obsolete cellular component	OBSOLETE. These are terms that have been removed from the active component ontology.	tmpzr1t_l9r_go_relaxed.owl						This term was made obsolete because it is unnecessary in the OBO flat file format.					True			cellular_component											owl:Class	
GO:0003931	biolink:NamedThing	obsolete Rho small monomeric GTPase activity	OBSOLETE. Catalysis of the reaction: GTP + H2O = GDP + phosphate. Any member of the Rho subfamily of the RAS superfamily of monomeric GTPases. Proteins in the Rho subfamily are involved in relaying signals from cell-surface receptors to the actin cytoskeleton.	tmpzr1t_l9r_go_relaxed.owl	Rho small monomeric GTPase activity			GO:0003924		This term was made obsolete because it represents a gene product.	GO:0007010				True			molecular_function											owl:Class	
GO:0071876	biolink:NamedThing	obsolete initiation of adrenergic receptor signal transduction	OBSOLETE. A process of signal initiation in which epinephrine or norepinephrine causes activation of an adrenergic receptor.	tmpzr1t_l9r_go_relaxed.owl	initiation of adrenergic receptor signal transduction					This term was made obsolete because the meaning of the term is ambiguous.	GO:0071872|GO:0005179|GO:0004935|GO:0071874|GO:0071875	mah	2010-09-13T04:05:38Z		True			biological_process											owl:Class	
GO:1990952	biolink:NamedThing	obsolete manchette disassembly	OBSOLETE. A cellular process that results in the breakdown of a manchette.	tmpzr1t_l9r_go_relaxed.owl	manchette clearance					This term was obsoleted at the TermGenie Gatekeeper stage.		krc	2016-05-11T00:14:16Z		True			biological_process											owl:Class	
GO:0045193	biolink:NamedThing	obsolete acetylated low-density lipoprotein catabolic process	OBSOLETE. The chemical reactions and pathways resulting in the breakdown of acetylated low-density lipoproteins.	tmpzr1t_l9r_go_relaxed.owl	Ac-LDL catabolic process|acetylated low-density lipoprotein catabolic process|acetylated low-density lipoprotein catabolism|acetylated low-density lipoprotein degradation|Ac-LDL catabolism|acetylated low-density lipoprotein breakdown					This term was made obsolete because low-density lipoprotein is a macromolecular complex, not a single class of molecule; its degradation involves the dissociation of non-covalently attached constituents as well as some breaking and reforming of covalent bonds.					True			biological_process											owl:Class	
GO:0001089	biolink:NamedThing	obsolete transcription factor activity, TFIIF-class transcription factor binding	OBSOLETE. Binding to a basal RNA polymerase II transcription factor of the TFIIF class in order to modulate transcription. The transcription factor may or may not also interact selectively with DNA as well.	tmpzr1t_l9r_go_relaxed.owl	TFIIF-class binding transcription factor activity					This term was obsoleted because it represents two separate functions. The corresponding 'binding' term should be used in combination with a transcription regulator activity child.	GO:0001096	krc	2010-10-28T02:27:12Z		True			molecular_function											owl:Class	
imports	biolink:NamedThing	imports		tmpzr1t_l9r_go_relaxed.owl					RO:0002340									external									imports			
GO:0030457	biolink:NamedThing	obsolete activation of MAPKK (mating sensu Fungi)	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	activation of MAPKK (mating sensu Fungi)			GO:0000750		This term was made obsolete because it is a gene product specific term.					True			biological_process											owl:Class	
GO:0043460	biolink:NamedThing	obsolete response to long exposure to lithium ion	OBSOLETE. A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a long or persistent exposure to a lithium ion stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to long exposure to lithium ion					This term was made obsolete because 'long' is not a quantitative or meaningful measurement of time.					True			biological_process											owl:Class	
GO:0006698	biolink:NamedThing	obsolete ecdysone modification	OBSOLETE. The covalent or conformational alteration of ecdysone, resulting in a change in its properties.	tmpzr1t_l9r_go_relaxed.owl	ecdysone modification			GO:0004501		This term was made obsolete because it was created to cover the conversion of ecdysone to its active form ecdysterone (20-hydroxyecdysone), but this reaction is carried out in a single step by ecdysone 20-monooxygenase (EC:1.14.99.22) and so is a function rather than a process.					True			biological_process											owl:Class	
GO:0005189	biolink:NamedThing	obsolete milk protein	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	milk protein					This term was made obsolete because it describes presence in body fluids rather than an activity.					True			molecular_function											owl:Class	
GO:1900473	biolink:NamedThing	obsolete negative regulation of phosphatidylcholine biosynthetic process by negative regulation of transcription from RNA polymerase II promoter	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of phosphatidylcholine biosynthetic process by stopping, preventing, or reducing the frequency, rate or extent of transcription from an RNA polymerase II promoter.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of phosphatidylcholine anabolism by negative regulation of transcription from RNA polymerase II promoter|negative regulation of phosphatidylcholine biosynthesis by negative regulation of transcription from RNA polymerase II promoter|negative regulation of phosphatidylcholine formation by negative regulation of transcription from RNA polymerase II promoter|negative regulation of phosphatidylcholine synthesis by negative regulation of transcription from RNA polymerase II promoter					This term was obsoleted because it represents a GO-CAM model.		dgf	2012-05-01T08:13:51Z		True			biological_process											owl:Class	
GO:0052479	biolink:NamedThing	obsolete negative regulation by organism of defense-related symbiont ethylene-mediated signal transduction pathway	OBSOLETE. Any process by which an organism stops, prevents, or reduces the frequency, rate or extent of symbiont ethylene-mediated signal transduction pathways during the symbiont defense response. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	negative regulation by organism of defense-related symbiont ethylene-mediated signal transduction pathway|suppression by organism of defense-related symbiont ethylene-mediated signal transduction pathway					This term was made obsolete because it does not represent a real biological process.					True			biological_process											owl:Class	
GO:0072466	biolink:NamedThing	obsolete detection of stimulus involved in cell shape checkpoint	OBSOLETE. The series of events in which information about aspects of cell polarity control is received and converted into a molecular signal, contributing to a cell shape checkpoint.	tmpzr1t_l9r_go_relaxed.owl	sensing involved in cell shape checkpoint|cell shape checkpoint sensor mechanism|cell shape checkpoint sensor process					This term was made obsolete because it was ambiguous.		mah	2010-12-09T11:43:58Z		True			biological_process											owl:Class	
GO:0090072	biolink:NamedThing	obsolete positive regulation of sodium ion transport via voltage-gated sodium channel activity	OBSOLETE. Any process that activates or increases the frequency, rate or extent of the directed movement of sodium ions via the activity of voltage-gated sodium channels.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of sodium ion transport via voltage-gated sodium channel activity					This term was made obsolete because it is ill-defined: channel activities are part of ion transport processes, and not the other way round.	GO:0005248	tb	2009-09-11T10:46:13Z		True			biological_process											owl:Class	
RO:0012008	biolink:NamedThing	results in fusion of		tmpzr1t_l9r_go_relaxed.owl					RO:0012008									external									results_in_fusion_of			
GO:0015307	biolink:NamedThing	obsolete drug:proton antiporter activity	OBSOLETE. Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + drug(in) = H+(in) + drug(out).	tmpzr1t_l9r_go_relaxed.owl	carbonyl cyanide m-chlorophenylhydrazone/nalidixic acid/organomercurials:hydrogen antiporter activity|drug:hydrogen antiporter activity					This term was obsoleted because it is not possible to state that every case of transmembrane transport for a specific chemical constitutes a drug transport.					True			molecular_function											owl:Class	
GO:0006923	biolink:NamedThing	obsolete cleavage of cytoskeletal proteins involved in execution phase of apoptosis	OBSOLETE. The proteolytic degradation of cytoskeletal proteins that contributes to apoptosis, leading to the collapse of cytoskeletal structures.	tmpzr1t_l9r_go_relaxed.owl	cleavage of cytoskeletal proteins involved in apoptosis|cleavage of cytoskeletal proteins involved in execution phase of apoptosis|apoptotic cleavage of cytoskeletal proteins					This term was obsoleted because it refers to targets of effector proteins (caspases); the 'cleavage' process referred to in the term name is in fact the same molecular function represented by GO:0097200 'cysteine-type endopeptidase activity involved in execution phase of apoptosis'.	GO:0097200				True			biological_process											owl:Class	
GO:0001597	biolink:NamedThing	obsolete apelin-like receptor	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	apelin-like receptor|APJ-like receptor					This term was made obsolete because the function it represents does not exist.	GO:0031704				True			molecular_function											owl:Class	
GO:0019873	biolink:NamedThing	obsolete tellurium sensitivity/resistance	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	tellurium sensitivity/resistance			GO:0046690		This term was made obsolete because 'sensitivity/resistance' implies a phenotype rather than a biological process.					True			biological_process											owl:Class	
GO:0044050	biolink:NamedThing	obsolete interaction with host via substance released by sporangium lysis	OBSOLETE. An interaction with the host organism mediated by a substance released via rupture of symbiont sporangia, structures producing and containing spores. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	interaction with host via substance released by sporangia lysis|interaction with host via substance released by lysis of symbiont sporangium					This term was obsoleted because it conflates a process and the mechanism of secretion of the gene product mediating the process.					True			biological_process											owl:Class	
GO:0101008	biolink:NamedThing	obsolete negative regulation of transcription from RNA polymerase II promoter in response to increased salt	OBSOLETE. Any process that decreases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of detection of, or exposure to, an increase in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/12739				This term was obsoleted because it represents a GO-CAM model.	GO:0000122|GO:0071472	mec			True			biological_process											owl:Class	
GO:0001316	biolink:NamedThing	obsolete age-dependent response to reactive oxygen species involved in replicative cell aging	OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) occurring during the process of replicative cell aging as a result of reactive oxygen species, where the change varies according to the age of the cell or organism.	tmpzr1t_l9r_go_relaxed.owl	age-dependent response to AOS during replicative cell aging|age-dependent response to reactive oxygen intermediate during replicative cell aging|age-dependent response to reactive oxygen species during replicative cell aging|age-dependent response to active oxygen species during replicative cell aging|age-dependent response to ROS during replicative cell aging|age-dependent response to reactive oxidative species during replicative cell aging|age-dependent response to reactive oxygen species during replicative cell ageing|age-dependent response to ROI during replicative cell aging	https://github.com/geneontology/go-ontology/issues/20007				This term was obsoleted because it represents an assay, not a true biological process.					True			biological_process											owl:Class	
GO:0005208	biolink:NamedThing	obsolete amyloid protein	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	amyloid protein					This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0009351	biolink:NamedThing	obsolete dihydrolipoamide S-acyltransferase complex	OBSOLETE. An enzyme complex that catalyzes the transfer of an acyl group from coenzyme A to dihydrolipoamide.	tmpzr1t_l9r_go_relaxed.owl	dihydrolipoamide S-acyltransferase complex					This term was made obsolete because dihydrolipoamide S-acyltransferase activity resides in a single polypeptide.					True			cellular_component											owl:Class	
GO:0001511	biolink:NamedThing	obsolete fibrillin	OBSOLETE. Large glycoprotein that is a calcium binding component of connective tissue microfibrils containing 34 six-cysteine (EGF-like) repeats and five eight-cysteine (TGFbeta-1 binding protein-like) repeats. Defects associated with Marfan syndrome.	tmpzr1t_l9r_go_relaxed.owl	fibrillin					This term was made obsolete because it represents a gene product.	GO:0005509|GO:0001527				True			molecular_function											owl:Class	
GO:0003798	biolink:NamedThing	obsolete male-specific antibacterial peptide activity	OBSOLETE. Inhibits the growth of, or directly kills, bacterial cells, but which is only expressed in males.	tmpzr1t_l9r_go_relaxed.owl	male-specific antibacterial peptide activity					This term was made obsolete because it describes involvement in a process and not a function.	GO:0050831				True			molecular_function											owl:Class	
GO:0030092	biolink:NamedThing	obsolete regulation of flagellum assembly	OBSOLETE. Any process that modulates the frequency, rate or extent of the formation of a flagellum.	tmpzr1t_l9r_go_relaxed.owl	regulation of flagellum biogenesis|regulation of flagella biogenesis|regulation of flagellum assembly|regulation of flagella assembly					This term was made obsolete because microtubule-based flagellum (GO:0009434) and motile cilium (GO:0031514), as referenced by this term, were determined to be equivalent and merged. When a merge for this term was considered, it was noticed that both eukaryotic and prokaryotic proteins are annotated to it because its meaning had been ambiguous so obsoletion was considered safest.	GO:1902017|GO:1902208				True			biological_process											owl:Class	
GO:0004193	biolink:NamedThing	obsolete cathepsin E activity	OBSOLETE. Catalysis of the hydrolysis of peptide bonds. Similar to cathepsin D, but slightly broader specificity.	tmpzr1t_l9r_go_relaxed.owl	non-pepsin proteinase activity|cathepsin E-like acid proteinase activity|EMAP|cathepsin D-like acid proteinase activity|cathepsin D-type proteinase activity|slow-moving proteinase activity|erythrocyte membrane aspartic proteinase activity|SMP|cathepsin E activity			GO:0004190		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0003673	biolink:NamedThing	obsolete Gene_Ontology	OBSOLETE. A controlled vocabulary that can be applied to all organisms even as knowledge of gene and protein roles in cells is accumulating and changing. GO provides three structured networks of defined terms to describe gene product attributes.	tmpzr1t_l9r_go_relaxed.owl	Gene_Ontology					This term was made obsolete because more specific terms were created.					True			biological_process											owl:Class	
GO:0030824	biolink:NamedThing	obsolete negative regulation of cGMP metabolic process	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving cGMP.	tmpzr1t_l9r_go_relaxed.owl	down regulation of cGMP metabolic process|down-regulation of cGMP metabolic process|downregulation of cGMP metabolic process|inhibition of cGMP metabolic process|negative regulation of cGMP metabolism					The reason for obsoletion is that the term represents the regulation of a signaling pathway, and not regulation of metabolism.					True			biological_process											owl:Class	
GO:1901204	biolink:NamedThing	obsolete regulation of adrenergic receptor signaling pathway involved in heart process	OBSOLETE. Any process that modulates the frequency, rate or extent of a cardiac adrenergic receptor signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	regulation of beta-adrenergic receptor signalling pathway involved in heart process|regulation of adrenergic receptor signalling pathway involved in heart process	https://github.com/geneontology/go-ontology/issues/14733				This term was obsoleted because it is not precise enough. We must specify if the ACA-activating or ACA inhibiting pathway is the target of the regulation.		hjd	2012-07-30T18:32:51Z		True			biological_process											owl:Class	
GO:0003818	biolink:NamedThing	obsolete complement factor I activity	OBSOLETE. Catalysis of the inactivation of complement subcomponents C3b, iC3b and C4b by proteolytic cleavage.	tmpzr1t_l9r_go_relaxed.owl	complement factor I activity|C3b/C4b inactivator activity|complement C3b/C4b inactivator|complement C4bi|complement C3b inactivator|complement component C3b inactivator activity|conglutinogen-activating factor C|complement C4b inactivator|C3b inactivator activity|C3bINA|factor I			GO:0004252		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GOREL:0002004	biolink:NamedThing	results_in_fission_of		tmpzr1t_l9r_go_relaxed.owl					GOREL:0002004									external									results_in_fission_of			
GO:0022014	biolink:NamedThing	obsolete radial glial cell division in subpallium	OBSOLETE. The division of a radial glial cell in the subpallium. A radial glial cell is a precursor cell that gives rise to neurons and astrocytes.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it represents a GO-CAM model.					True			biological_process											owl:Class	
GO:0005038	biolink:NamedThing	obsolete death receptor interacting protein activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	death receptor interacting protein activity					This term was made obsolete because it represents a gene product and not a molecular function.	GO:0005515|GO:0005123				True			molecular_function											owl:Class	
GO:0052177	biolink:NamedThing	obsolete metabolism by symbiont of host xylan	OBSOLETE. The chemical reactions and pathways performed by an organism involving xylan within the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/21396				This term was obsoleted because it represents an unnecessary grouping class.					True			biological_process											owl:Class	
GO:0016659	biolink:NamedThing	obsolete oxidoreductase activity, acting on NADH or NADPH, other acceptor	OBSOLETE. Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces an acceptor other than disulfide, a heme protein, NAD, NADP, a nitrogenous group, a quinone or similar compound or oxygen.	tmpzr1t_l9r_go_relaxed.owl	oxidoreductase activity, acting on NADH or NADPH, other acceptor					This term was made obsolete because it was an unnecessary grouping term.	GO:0016651				True			molecular_function											owl:Class	
GO:0030303	biolink:NamedThing	obsolete stromelysin 2 activity	OBSOLETE. Catalysis of the cleavage of peptide bonds in collagen with preferential cleavage where P1', P2' and P3' are hydrophobic residues; action on collagen types III, IV and V is weak.	tmpzr1t_l9r_go_relaxed.owl	proteoglycanase 2|matrix metalloproteinase 10 activity|stromelysin 2 activity|MMP-10|transin 2 activity			GO:0004222		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0030828	biolink:NamedThing	obsolete positive regulation of cGMP biosynthetic process	OBSOLETE. Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cGMP.	tmpzr1t_l9r_go_relaxed.owl	upregulation of cGMP biosynthetic process|stimulation of cGMP biosynthetic process|positive regulation of cGMP formation|up-regulation of cGMP biosynthetic process|up regulation of cGMP biosynthetic process|positive regulation of cGMP anabolism|positive regulation of cGMP biosynthesis|positive regulation of cGMP synthesis|activation of cGMP biosynthetic process					The reason for obsoletion is that this term represent the regulation of a signaling pathway,  not regulation of metabolism.	GO:0004383				True			biological_process											owl:Class	
GO:0033124	biolink:NamedThing	obsolete regulation of GTP catabolic process	OBSOLETE. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of GTP, guanosine triphosphate.	tmpzr1t_l9r_go_relaxed.owl	regulation of GTP catabolism|regulation of GTP breakdown|regulation of GTP degradation					The reason for making this term obsolete is that it gets misused in cases where phosphates are simply being removed from a small molecule. We found no cases where these molecules genuinely underwent catabolism.	GO:0043087				True			biological_process											owl:Class	
GO:0046235	biolink:NamedThing	obsolete gallate biosynthetic process	OBSOLETE. The chemical reactions and pathways resulting in the formation of gallate, the anion of gallic acid (3,4,5-trihydroxybenzoic acid).	tmpzr1t_l9r_go_relaxed.owl	gallate formation|gallic acid biosynthesis|gallate biosynthesis|gallate anabolism|gallic acid biosynthetic process|gallate synthesis					This term was obsoleted because there is no evidence that this process exists.					True			biological_process											owl:Class	
GO:0030304	biolink:NamedThing	obsolete trypsin inhibitor activity	OBSOLETE. Stops, prevents or reduces the activity of the serine endopeptidase trypsin.	tmpzr1t_l9r_go_relaxed.owl	trypsin inhibitor activity			GO:0004867		This term was made obsolete because it represents a regulator of an obsolete molecular function.					True			molecular_function											owl:Class	
GO:0006133	biolink:NamedThing	obsolete 5,10-methylenetetrahydrofolate oxidation	OBSOLETE. This term was not defined before being made obsolete.	tmpzr1t_l9r_go_relaxed.owl	5,10-methylenetetrahydrofolate oxidation					This term was made obsolete because it is defined as a function term and is in the process ontology.	GO:0004488|GO:0033738|GO:0004487|GO:0004489				True			biological_process											owl:Class	
GO:0106198	biolink:NamedThing	obsolete translocase activity acting on inorganic anions linked to a decarboxylation reaction	OBSOLETE. Catalysis of the translocation of an inorganic anion linked to a decarboxylation reaction.	tmpzr1t_l9r_go_relaxed.owl					EC:7.3.4.-	This term was made obsolete because the concept of using the non-4 digit EC classes as parent terms for the transporter banch of the onotolgy was consided confusing.		hjd	2019-05-08T18:20:14Z		True			molecular_function											owl:Class	
GO:0023062	biolink:NamedThing	obsolete signal transmission via transcytosis	OBSOLETE. The process in which a signal is conveyed via transcytosis. Transcytosis is the directed movement of endocytosed material through the cell and its exocytosis from the plasma membrane at the opposite side.	tmpzr1t_l9r_go_relaxed.owl	signal transmission via transcytosis					This term was made obsolete because the meaning of the term is ambiguous.	GO:0023052|GO:0045056		2010-02-16T09:30:50Z		True			biological_process											owl:Class	
GO:0043747	biolink:NamedThing	obsolete N2-acetyl-L-lysine deacetylase activity	OBSOLETE. Catalysis of the reaction: N2-acetyl-L-lysine + H2O = acetate + L-lysine.	tmpzr1t_l9r_go_relaxed.owl	N-acetyl-lysine deacetylase activity	https://github.com/geneontology/go-ontology/issues/18908			RHEA:28598|MetaCyc:RXN-5185	This term was obsoleted because there is no evidence that it exists.					True			molecular_function											owl:Class	
GO:0052236	biolink:NamedThing	obsolete negative chemotaxis on or near other organism involved in symbiotic interaction	OBSOLETE. The directed movement of a motile cell or organism towards a lower concentration of a specific chemical on or near a second organism, where the two organisms are in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	negative chemotaxis on or near other organism during symbiotic interaction	https://github.com/geneontology/go-ontology/issues/18819				This term was obsoleted because it represents both a process and a location.					True			biological_process											owl:Class	
GO:0009498	biolink:NamedThing	obsolete bacterial-type ferredoxin	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	bacterial-type ferredoxin			GO:0009055		This term was made obsolete because it does not represent a function.					True			molecular_function											owl:Class	
GO:0043459	biolink:NamedThing	obsolete response to short exposure to lithium ion	OBSOLETE. A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a single or short exposure to a lithium ion stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to short exposure to lithium ion					This term was made obsolete because 'short' is not a quantitative or meaningful measurement of time.					True			biological_process											owl:Class	
RO:0002295	biolink:NamedThing	results in developmental progression of		tmpzr1t_l9r_go_relaxed.owl					RO:0002295									external									results_in_developmental_progression_of			
GO:0034648	biolink:NamedThing	obsolete histone demethylase activity (H3-dimethyl-K4 specific)	OBSOLETE. Catalysis of the removal of a methyl group from dimethylated lysine at position 4 of the histone H3 protein.	tmpzr1t_l9r_go_relaxed.owl	histone demethylase activity (H3-K4-me2 specific)	https://github.com/geneontology/go-ontology/issues/21089				This term was obsoleted to align with RHEA and EC: this is a sub-reaction both in RHEA:60208 and EC:1.14.11.67.	GO:0140682|GO:0034647				True			molecular_function											owl:Class	
GO:0100053	biolink:NamedThing	obsolete positive regulation of sulfate assimilation by transcription from RNA polymerase II promoter	OBSOLETE. Any transcription from RNA polymerase II promoter process that positively regulates sulfate assimilation.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it represents a GO-CAM model.		cjm	2015-04-02T04:13:19Z		True			biological_process											owl:Class	
GO:0006252	biolink:NamedThing	obsolete CTP reduction	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	CTP reduction					This term was made obsolete because it represents a molecular function rather than a biological process.	GO:0051065				True			biological_process											owl:Class	
GO:0106178	biolink:NamedThing	obsolete translocase activity	OBSOLETE. Catalysis the movement of ions or molecules across membranes or their separation within membranes.	tmpzr1t_l9r_go_relaxed.owl					EC:7.-.-.-	This term was made obsolete because the concept of using the non-4 digit EC classes as parent terms for the transporter banch of the onotolgy was consided confusing.		hjd	2019-04-05T15:41:06Z		True			molecular_function											owl:Class	
GO:0006943	biolink:NamedThing	obsolete chemi-mechanical coupling	OBSOLETE. The conversion of chemical energy into mechanical work (as in the contraction of a muscle).	tmpzr1t_l9r_go_relaxed.owl	mechanochemical coupling|chemi-mechanical coupling					This term was made obsolete because its meaning is vague, and it does not fit with other terms in GO.	GO:0009612|GO:0050954				True			biological_process											owl:Class	
GO:0045097	biolink:NamedThing	obsolete basic/neutral keratin	OBSOLETE. A type of intermediate filament.	tmpzr1t_l9r_go_relaxed.owl	type II intermediate filament|basic/neutral keratin			GO:0045095		This term was made obsolete because it represents a gene product.					True			cellular_component											owl:Class	
GO:0052505	biolink:NamedThing	obsolete positive regulation by organism of defense-related symbiont cell wall callose deposition	OBSOLETE. Any process by which an organism activates, maintains or increases the frequency, rate or extent of the deposition of callose by the symbiont in its cell walls, occurring as part of the defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	positive regulation by organism of defense-related symbiont cell wall callose deposition|induction by organism of defense-related symbiont cell wall callose deposition					This term was made obsolete because it does not represent a real biological process.					True			biological_process											owl:Class	
GO:0052416	biolink:NamedThing	obsolete metabolism by host of symbiont macromolecule	OBSOLETE. The chemical reactions and pathways performed by an organism involving macromolecules within the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/21469				This term was obsoleted because it represents a molecular function.					True			biological_process											owl:Class	
GO:0031377	biolink:NamedThing	obsolete mitochondrial type II fatty acid synthase complex	OBSOLETE. A fatty acid synthase complex in which each polypeptide chain catalyzes a single activity, located in the mitochondrion.	tmpzr1t_l9r_go_relaxed.owl	mitochondrial type II FAS complex|mitochondrial type II fatty acid synthase complex					Obsoleted because type II fatty acid synthases are not complexes					True			cellular_component											owl:Class	
GO:1900547	biolink:NamedThing	obsolete negative regulation of phenotypic switching by regulation of transcription from RNA polymerase II promoter	OBSOLETE. A regulation of transcription from RNA polymerase II promoter that results in negative regulation of phenotypic switching.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of phenotypic dimorphism by regulation of transcription from RNA polymerase II promoter					This term was obsoleted because it represents a GO-CAM model.		di	2012-05-14T11:40:54Z		True			biological_process											owl:Class	
GO:1990908	biolink:NamedThing	obsolete Lys63-specific zinc metallopeptidase deubiquitinase activity	OBSOLETE. Hydrolysis of Lys63-Linked ubiquitin unit(s) from a ubiquitinated protein by a mechanism where zinc acts as the nucleophile.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted at the TermGenie Gatekeeper stage.		al	2015-12-03T14:25:04Z		True			molecular_function											owl:Class	
GO:0048277	biolink:NamedThing	obsolete nonexocytotic vesicle docking	OBSOLETE. The initial attachment of a transport vesicle membrane to a target membrane, mediated by proteins protruding from the membrane of the vesicle and the target membrane, during a non-exocytotic process.	tmpzr1t_l9r_go_relaxed.owl	nonexocytotic vesicle docking|non-exocytotic vesicle docking			GO:0048278		This term was made obsolete because it violates the principle of positivity.					True			biological_process											owl:Class	
GO:0032524	biolink:NamedThing	obsolete nutrient export	OBSOLETE. The directed movement of nutrients out of a cell or organelle.	tmpzr1t_l9r_go_relaxed.owl	nutrient export					This term was made obsolete because "nutrient" is not defined, and does not have a consistent meaning.	GO:0006810				True			biological_process											owl:Class	
GO:0100043	biolink:NamedThing	obsolete negative regulation of cellular response to alkaline pH by transcription from RNA polymerase II promoter	OBSOLETE. Any transcription from RNA polymerase II promoter process that negatively regulates cellular response to alkaline pH.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it represents a GO-CAM model.		cjm	2015-04-02T04:13:19Z		True			biological_process											owl:Class	
GO:0035826	biolink:NamedThing	obsolete rubidium ion transport	OBSOLETE. The directed movement of rubidium ions (Rb+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl	Rb+ transport|rubidium cation transport					This term has been obsoleted because it represents an assay, and not a physiological process.		bf	2011-05-04T02:53:27Z		True			biological_process											owl:Class	
GO:0019832	biolink:NamedThing	obsolete mercuric sensitivity/resistance	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	mercuric sensitivity/resistance			GO:0046689		This term was made obsolete because 'sensitivity/resistance' implies a phenotype rather than a biological process.					True			biological_process											owl:Class	
GO:0044146	biolink:NamedThing	obsolete negative regulation of growth of symbiont involved in interaction with host	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the increase in size or mass of an organism occurring in, on or near the exterior of its host organism.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of growth of symbiont during interaction with host					This term was obsoleted because it was partially redundant with other terms and its usage has been inconsistent.		jl	2009-08-06T02:04:24Z		True			biological_process											owl:Class	
GO:0000231	biolink:NamedThing	obsolete cytoplasmic mitotic chromosome	OBSOLETE. A chromosome found in the cytoplasm during mitosis.	tmpzr1t_l9r_go_relaxed.owl	cytoplasmic mitotic chromosome					This term was made obsolete because it is based on a temporal division of the cell cycle.	GO:0000793				True			cellular_component											owl:Class	
GO:0071530	biolink:NamedThing	obsolete FHA domain-mediated complex assembly	OBSOLETE. A process of protein complex assembly in which the arrangement and bonding together of the set of components that form the protein complex is mediated by an FHA (forkhead-associated) domain interaction.	tmpzr1t_l9r_go_relaxed.owl	forkhead-associated domain-mediated complex assembly					This term was obsoleted because it represented a molecular function (binding), not a biological process.  The term represented a domain involved in protein-protein interactions, but no necessarily the process of assembling a complex.		mah	2010-01-08T01:57:36Z		True			biological_process											owl:Class	
GO:0070018	biolink:NamedThing	obsolete transforming growth factor beta type I receptor homodimeric complex	OBSOLETE. A receptor complex that consists of two transforming growth factor beta (TGF-beta) type I receptor monomers. TGF-beta type I receptor dimers form in the presence or absence of ligand, and can associate with ligand-bound TGF-beta type II receptor dimers.	tmpzr1t_l9r_go_relaxed.owl	TGF-beta type I receptor dimer|TGFBR1 homodimer|transforming growth factor beta type I receptor complex|TGF-beta type I receptor complex	https://github.com/geneontology/go-ontology/issues/12676				This term was made obsolete because it does not represent a physiological complex.					True			cellular_component											owl:Class	
GO:0097015	biolink:NamedThing	obsolete bacterial-type flagellar cytoplasm	OBSOLETE. All of the contents of a bacterial-type flagellum, excluding the plasma membrane surrounding the flagellum.	tmpzr1t_l9r_go_relaxed.owl	bacterial-type flagellum cytoplasm					The reason for obsoletion is that this term describes a cellular component that does not exist.		pr	2011-03-23T01:59:44Z		True			cellular_component											owl:Class	
GO:0019214	biolink:NamedThing	obsolete surfactant activity	OBSOLETE. The action of reducing the surface tension of a liquid.	tmpzr1t_l9r_go_relaxed.owl	surfactant activity					This term was made obsolete because it represents involvement in a process.	GO:0050828				True			molecular_function											owl:Class	
GO:0035555	biolink:NamedThing	obsolete initiation of Roundabout signal transduction	OBSOLETE. The process in which a SLIT protein causes activation of the receptor, Roundabout (ROBO).	tmpzr1t_l9r_go_relaxed.owl	initiation of Roundabout signal transduction					This term was made obsolete because the meaning of the term is ambiguous.	GO:0048495|GO:0035385|GO:0038023	bf	2010-05-14T11:10:20Z		True			biological_process											owl:Class	
GO:0018135	biolink:NamedThing	obsolete peptidyl-cysteine cyclase activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	peptidyl-cysteine cyclase activity				EC:4.2.1.-	This term was made obsolete because there is no record of why it was added, and no evidence can be found to suggest that this activity exists.					True			molecular_function											owl:Class	
GO:0052394	biolink:NamedThing	obsolete induction by organism of defense-related symbiont cell wall thickening	OBSOLETE. Any process by which an organism activates, maintains or increases the frequency, rate or extent of symbiont processes resulting in the thickening of its cell walls, occurring as part of the defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	induction by organism of defense-related symbiont cell wall thickening|activation by organism of symbiont defense-related cell wall thickening|activation by organism of symbiont defensive cell wall thickening|induction by organism of symbiont defensive cell wall thickening					This term was made obsolete because it does not represent a real biological process.					True			biological_process											owl:Class	
GO:0071899	biolink:NamedThing	obsolete negative regulation of estrogen receptor binding	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of estrogen receptor binding, interacting selectively with an estrogen receptor.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/19354				This term was obsoleted because it represents a molecular function.		mah	2010-09-15T02:51:10Z		True			biological_process											owl:Class	
GO:0007363	biolink:NamedThing	obsolete positive regulation of terminal gap gene transcription	OBSOLETE. The activation of genes encoding transcription factors at the anterior and posterior ends of an insect embryo by a combination of maternal regulatory signals and interactions among themselves; exemplified by the activation of expression of the Drosophila tailless and huckebein genes.	tmpzr1t_l9r_go_relaxed.owl	upregulation of terminal gap gene transcription|up regulation of terminal gap gene transcription|activation of terminal gap gene transcription|stimulation of terminal gap gene transcription|up-regulation of terminal gap gene transcription|activation of terminal gap gene					This term was obsoleted because it represents a GO-CAM model.					True			biological_process											owl:Class	
GO:1905925	biolink:NamedThing	obsolete negative regulation of invadopodium assembly	OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of invadopodium assembly.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of invadopodium assembly|inhibition of invadopodium formation|down regulation of invadopodium formation|down-regulation of invadopodium formation|negative regulation of invadopodium formation|down regulation of invadopodium assembly|inhibition of invadopodium assembly|downregulation of invadopodium formation|downregulation of invadopodium assembly					This term was made obsolete because an invadopodium is an abnormal structure found in cancerous or transformed cells that is out of scope of GO.		sl	2017-02-08T21:38:39Z		True			biological_process											owl:Class	
GO:0100069	biolink:NamedThing	obsolete negative regulation of neuron apoptotic process by transcription from RNA polymerase II promoter	OBSOLETE. Any transcription from RNA polymerase II promoter process that negatively regulates neuron apoptotic process.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it represents a GO-CAM model.		cjm	2015-04-02T04:13:19Z		True			biological_process											owl:Class	
GO:0052143	biolink:NamedThing	obsolete chemotaxis on or near host involved in symbiotic interaction	OBSOLETE. The directed movement of a motile cell or organism in response to a specific chemical concentration gradient on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	chemotaxis on or near host during symbiotic interaction	https://github.com/geneontology/go-ontology/issues/18819				This term was obsoleted because it represents both a process and a location.					True			biological_process											owl:Class	
GO:1900413	biolink:NamedThing	obsolete positive regulation of phospholipid biosynthetic process by positive regulation of transcription from RNA polymerase II promoter	OBSOLETE. A positive regulation of transcription from RNA polymerase II promoter that results in positive regulation of phospholipid biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of phospholipid biosynthesis by positive regulation of transcription from RNA polymerase II promoter|positive regulation of phospholipid synthesis by positive regulation of transcription from RNA polymerase II promoter					This term was obsoleted because it represents a GO-CAM model.		mah	2012-04-20T03:41:58Z		True			biological_process											owl:Class	
GO:0100063	biolink:NamedThing	obsolete regulation of dipeptide transmembrane transport by transcription from RNA polymerase II promoter	OBSOLETE. Any transcription from RNA polymerase II promoter process that regulates dipeptide transmembrane transport.	tmpzr1t_l9r_go_relaxed.owl						The term was obsoleted because it is better represented by a GO-CAM model.		cjm	2015-04-02T04:13:19Z		True			biological_process											owl:Class	
GO:0052374	biolink:NamedThing	obsolete negative regulation by symbiont of entry into host	OBSOLETE. Any process in which an organism stops, prevents, or reduces the frequency, rate or extent to which it enters into the host organism, where the two organisms are in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	downregulation by symbiont of entry into host|down-regulation by symbiont of entry into host|down regulation by symbiont of entry into host|inhibition by symbiont of entry into host	https://github.com/geneontology/go-ontology/issues/18779				This term was obsoleted because there is no evidence that this process exists.					True			biological_process											owl:Class	
GO:0004212	biolink:NamedThing	obsolete lysosomal cysteine-type endopeptidase	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	lysosomal cysteine-type endopeptidase					This term was made obsolete because it contains both component and function information.	GO:0005764|GO:0004197				True			molecular_function											owl:Class	
GO:0006800	biolink:NamedThing	obsolete oxygen and reactive oxygen species metabolic process	OBSOLETE. The chemical reactions and pathways involving dioxygen (O2), or any of the reactive oxygen species, e.g. superoxide anions (O2-), hydrogen peroxide (H2O2), and hydroxyl radicals (-OH).	tmpzr1t_l9r_go_relaxed.owl	oxygen and ROS metabolic process|oxygen and reactive oxygen species metabolic process|oxygen and ROI metabolism|oxygen and reactive oxygen species metabolism|oxygen and active oxygen species metabolism|oxygen and reactive oxidative species metabolism|oxygen and ROS metabolism|oxygen and AOS metabolism|oxygen and reactive oxygen intermediate metabolism					This term was made obsolete because, as part of the GO/ChEBI alignment effort, curators determined that oxygen and reactive oxygen species should not be grouped together.	GO:0072593|GO:0072592				True			biological_process											owl:Class	
GO:0052210	biolink:NamedThing	obsolete interaction with other organism via protein secreted by type III secretion system involved in symbiotic interaction	OBSOLETE. An interaction with a second organism mediated by a substance secreted by the first organism by a type III secretion system, where the two organisms are in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	interaction with other organism via protein secreted by type III secretion system during symbiotic interaction					This term was obsoleted because it conflated the process in which a gene product is involved with the secretion system by which it reaches its target.					True			biological_process											owl:Class	
GO:0031659	biolink:NamedThing	obsolete positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle	OBSOLETE. Any process that activates or increases the frequency, rate or extent of cyclin-dependent protein serine/threonine kinase activity contributing to the G1/S transition of the cell cycle.	tmpzr1t_l9r_go_relaxed.owl	G1/S-specific up regulation of cyclin-dependent protein kinase activity|G1/S-specific up-regulation of cyclin-dependent protein kinase activity|G1/S-specific positive regulation of cyclin-dependent protein kinase activity|positive regulation of cyclin-dependent protein kinase activity during G1/S|G1/S-specific activation of cyclin-dependent protein kinase activity|G1/S-specific stimulation of cyclin-dependent protein kinase activity|G1/S-specific upregulation of cyclin-dependent protein kinase activity|positive regulation of cyclin-dependent protein kinase activity involved in G1/S					The term has been obsoleted because it represents a GO-CAM model.					True			biological_process											owl:Class	
GO:0023067	biolink:NamedThing	obsolete signal transmission via lymphatic system	OBSOLETE. The process in which a signal is conveyed via the lymphatic system.	tmpzr1t_l9r_go_relaxed.owl	signal transmission via lymphatic system					This term was made obsolete because the meaning of the term is ambiguous.	GO:0023052		2010-02-16T09:30:50Z		True			biological_process											owl:Class	
GO:0030404	biolink:NamedThing	obsolete collagenase 3 activity	OBSOLETE. Was not defined before being made obsolete.	tmpzr1t_l9r_go_relaxed.owl	MMP-13|matrix metalloproteinase 13|collagenase 3 activity			GO:0004252		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0003074	biolink:NamedThing	obsolete regulation of diuresis	OBSOLETE. Any process that modulates the rate of diuresis. Diuresis is the process of renal water excretion.	tmpzr1t_l9r_go_relaxed.owl	regulation of diuresis					This term was made obsolete because its definition was inaccurate.	GO:0035809				True			biological_process											owl:Class	
GO:0072367	biolink:NamedThing	obsolete regulation of lipid transport by regulation of transcription from RNA polymerase II promoter	OBSOLETE. Any process that modulates the frequency, rate or extent of lipid transport by modulating the frequency, rate or extent of transcription from an RNA polymerase II promoter.	tmpzr1t_l9r_go_relaxed.owl	regulation of lipid transport by regulation of transcription from an RNA polymerase II promoter					This term was obsoleted because it represents a GO-CAM model.		mah	2010-11-16T03:17:54Z		True			biological_process											owl:Class	
GO:0052174	biolink:NamedThing	obsolete metabolism by symbiont of host macromolecule	OBSOLETE. The chemical reactions and pathways performed by an organism involving macromolecules within the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/21469				This term was obsoleted because it represents a molecular function.					True			biological_process											owl:Class	
GO:0005054	biolink:NamedThing	obsolete peroxisome integral membrane receptor	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	peroxisome integral membrane receptor|Pas20p					This term was made obsolete because it describes a cellular component.	GO:0038023				True			molecular_function											owl:Class	
GO:0051181	biolink:NamedThing	obsolete cofactor transport	OBSOLETE. The directed movement of a cofactor into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A cofactor is a substance that is required for the activity of an enzyme or other protein.	tmpzr1t_l9r_go_relaxed.owl	vitamin or cofactor transport					1. Making inferences in GO about compounds based on the cofactor role curated by ChEBI creates relationships that are not always true which violates ontological principles for GO; therefore we will cease making these inferences. 2. It is not meaningful to group transport processes that are not all chemically related by the fact that they may be used as a cofactor.					True			biological_process											owl:Class	
GO:0009494	biolink:NamedThing	obsolete chloroplast-type ferredoxin	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	chloroplast-type ferredoxin			GO:0009055		This term was made obsolete because it does not represent a function.					True			molecular_function											owl:Class	
GO:0004281	biolink:NamedThing	obsolete pancreatic elastase II activity	OBSOLETE. Catalysis of the preferential cleavage of Leu-Xaa, Met-Xaa and Phe-Xaa. Hydrolyzes elastin.	tmpzr1t_l9r_go_relaxed.owl	pancreatic elastase II activity|pancreatic elastase 2			GO:0004252		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:1990271	biolink:NamedThing	obsolete anti-Mullerian hormone	OBSOLETE. Combining with anti-Mullerian hormone to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	anti-Mullerian hormone					An example of this is Amdh2 in M. musculus, UniprotKB:Q8K592-1 in PMID:23624077.		hjd	2014-01-14T20:38:39Z		True			molecular_function											owl:Class	
GO:0052216	biolink:NamedThing	obsolete chemotaxis in environment of other organism involved in symbiotic interaction	OBSOLETE. The directed movement of a motile cell or organism in response to a specific chemical concentration gradient on, within or near a second organism, where the two organisms are in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	chemotaxis in environment of other organism during symbiotic interaction|chemotaxis in response to environment of other organism	https://github.com/geneontology/go-ontology/issues/18819				This term was obsoleted because it represents both a process and a location.					True			biological_process											owl:Class	
GO:0052414	biolink:NamedThing	obsolete metabolism by host of symbiont glucan	OBSOLETE. The chemical reactions and pathways performed by an organism involving glucans within the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/21469				This term was obsoleted because it represents a molecular function.					True			biological_process											owl:Class	
GO:0004600	biolink:NamedThing	obsolete cyclophilin	OBSOLETE. A protein to which cyclosporin A (an immunosuppressant) binds. Possesses peptidyl-prolyl isomerase activity.	tmpzr1t_l9r_go_relaxed.owl	cyclophilin					This term was made obsolete because it does not represent a molecular function.	GO:0016018|GO:0003755				True			molecular_function											owl:Class	
GO:0009495	biolink:NamedThing	obsolete thioredoxin-like 2Fe-2S ferredoxin	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	thioredoxin-like 2Fe-2S ferredoxin			GO:0009055		This term was made obsolete because it does not represent a function.					True			molecular_function											owl:Class	
GO:0007070	biolink:NamedThing	obsolete negative regulation of transcription from RNA polymerase II promoter during mitotic cell cycle	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of transcription from an RNA polymerase II promoter that occurs during the mitotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl	down regulation of transcription from RNA polymerase II promoter during mitosis|negative regulation of transcription from Pol II promoter during mitosis|inhibition of transcription from RNA polymerase II promoter during mitosis|negative regulation of transcription from RNA polymerase II promoter, mitotic|mitotic repression of transcription from Pol II promoter|down-regulation of transcription from RNA polymerase II promoter during mitosis|downregulation of transcription from RNA polymerase II promoter during mitosis	https://github.com/geneontology/go-ontology/issues/14896				The reason for obsoletion is that 'during' should be captured using an annotation extension.	GO:0044772|GO:0000122				True			biological_process											owl:Class	
GO:1990803	biolink:NamedThing	obsolete protein phosphorylation involved in protein localization to spindle microtubule	OBSOLETE. Any protein phosphorylation process involved in localizing a protein to the spindle microtubule.	tmpzr1t_l9r_go_relaxed.owl	protein phosphorylation involved in protein localisation to spindle microtubule|protein amino acid phosphorylation involved in protein localisation in spindle microtubule|protein amino acid phosphorylation involved in protein localization in spindle microtubule|protein phosphorylation involved in protein localisation in spindle microtubule|protein amino acid phosphorylation involved in protein localisation to spindle microtubule|protein phosphorylation involved in protein localization in spindle microtubule|protein amino acid phosphorylation involved in protein localization to spindle microtubule	https://github.com/geneontology/go-ontology/issues/14137				This term has been obsoleted because it represents a GO-CAM model.		rb	2015-07-16T21:09:07Z		True			biological_process											owl:Class	
GO:1904720	biolink:NamedThing	obsolete regulation of mRNA endonucleolytic cleavage involved in unfolded protein response	OBSOLETE. Any process that modulates the frequency, rate or extent of mRNA endonucleolytic cleavage involved in unfolded protein response.	tmpzr1t_l9r_go_relaxed.owl	regulation of HAC1-type intron splice site recognition and cleavage|regulation of IRE1-mediated XBP-1 mRNA cleavage|regulation of XBP1 mRNA cleavage|regulation of HAC1 mRNA cleavage					The reason for obsoletion is that this process being regulated (GO:0070055 mRNA endonucleolytic cleavage involved in unfolded protein response) was obsoleted.	GO:1903895	bf	2015-10-08T14:52:49Z		True			biological_process											owl:Class	
GO:0010671	biolink:NamedThing	obsolete negative regulation of oxygen and reactive oxygen species metabolic process	OBSOLETE. Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving dioxygen (O2), or any of the reactive oxygen species, e.g. superoxide anions (O2-), hydrogen peroxide (H2O2), and hydroxyl radicals (-OH).	tmpzr1t_l9r_go_relaxed.owl	negative regulation of oxygen and reactive oxygen species metabolic process					This term was made obsolete because, as part of the GO/ChEBI alignment effort, curators determined that oxygen and reactive oxygen species should not be grouped together.	GO:2000378|GO:2000375				True			biological_process											owl:Class	
GO:0052190	biolink:NamedThing	obsolete modulation by symbiont of host phagocytosis	OBSOLETE. Any process in which an organism modulates the frequency, rate or extent of phagocytosis, the engulfing by phagocytes of external particulate material, in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/18562				This term was obsoleted because there is no evidence that this process exists.					True			biological_process											owl:Class	
GO:0052353	biolink:NamedThing	obsolete catabolism by host of symbiont carbohydrate	OBSOLETE. The chemical reactions and pathways performed by an organism resulting in the breakdown of carbohydrate molecules within the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/21469				This term was obsoleted because it represents a molecular function.					True			biological_process											owl:Class	
GO:0052343	biolink:NamedThing	obsolete positive regulation by organism of symbiont phytoalexin production	OBSOLETE. Any process in which an organism activates, maintains or increases the frequency, rate or extent of the production of phytoalexins as part of the defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	positive regulation by organism of symbiont phytoalexin production					This term was made obsolete because it does not represent a real biological process.					True			biological_process											owl:Class	
GO:1901635	biolink:NamedThing	obsolete regulation of maintenance of presynaptic active zone structure	OBSOLETE. Any process that modulates the frequency, rate or extent of maintenance of presynaptic active zone structure.	tmpzr1t_l9r_go_relaxed.owl	regulation of maintenance of presynaptic active zone structure					This term was obsoleted at the TermGenie Gatekeeper stage.		ans	2012-11-15T14:17:03Z		True			biological_process											owl:Class	
GO:0006804	biolink:NamedThing	obsolete peroxidase reaction	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	peroxidase reaction			GO:0004601		This term was made obsolete because it represents a molecular function.					True			biological_process											owl:Class	
GO:0044007	biolink:NamedThing	obsolete dissemination or transmission of symbiont from host	OBSOLETE. The movement of an organism from a host to another host or from a host to another place in the environment. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	dissemination or transmission of organism from host					This term was obsoleted because it did not represent a specific process, but represented the life cycle of a symbiont.					True			biological_process											owl:Class	
GO:0075108	biolink:NamedThing	obsolete negative regulation by symbiont of host adenylate cyclase activity	OBSOLETE. Any process in which the symbiont stops, prevents, or reduces the frequency, rate or extent of the host adenylate cyclase activity, which catalyze the reaction: ATP = 3',5'-cyclic AMP + diphosphate. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	Negative regulation by symbiont of host ATP pyrophosphate-lyase activity|Negative regulation by symbiont of host cAMP generating peptide activity|Negative regulation by symbiont of host adenylylcyclase activity|Negative regulation by symbiont of host 3',5'-cyclic AMP synthetase activity|Negative regulation by symbiont of host adenyl cyclase activity|Negative regulation by symbiont of host ATP diphosphate-lyase (cyclizing ; 3',5'-cyclic-AMP-forming) activity|Negative regulation by symbiont of host ATP diphosphate-lyase (cyclizing) activity|Negative regulation by symbiont of host adenylyl cyclase activity					This term was obsoleted because it represents a molecular function.					True			biological_process											owl:Class	
GO:0033237	biolink:NamedThing	obsolete 11-beta-hydroxysteroid dehydrogenase (NADP+) activity	OBSOLETE. Catalysis of the reaction: an 11-beta-hydroxysteroid + NADP+ = an 11-oxosteroid + NADPH + H+.	tmpzr1t_l9r_go_relaxed.owl	corticosteroid 11-beta-dehydrogenase activity|beta-hydroxysteroid dehydrogenase|11beta-hydroxysteroid:NADP+ 11-oxidoreductase|11-beta-hydroxysteroid dehydrogenase (NADP+) activity			GO:0070524							True			molecular_function											owl:Class	
GO:0061434	biolink:NamedThing	obsolete regulation of replicative cell aging by regulation of transcription from RNA polymerase II promoter in response to caloric restriction	OBSOLETE. Any process that modulates the frequency, rate or extent of replicative cell aging through a mechanism that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a caloric restriction stimulus.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it represents a GO-CAM model.	GO:0090398|GO:0006357	dph	2012-02-09T09:06:09Z		True			biological_process											owl:Class	
GO:0051420	biolink:NamedThing	obsolete nebulette binding	OBSOLETE. Binding to nebulette, a 107 kDa protein associated with the I-Z-I complex of cardiac myofibrils. It shows a high degree of homology with skeletal muscle nebulin.	tmpzr1t_l9r_go_relaxed.owl	nebulette binding			GO:0008092		This term was made obsolete because it represents binding to an individual protein.					True			molecular_function											owl:Class	
GO:0072363	biolink:NamedThing	obsolete regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter	OBSOLETE. Any process that modulates the frequency, rate or extent of glycolysis by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter.	tmpzr1t_l9r_go_relaxed.owl	regulation of glycolysis by positive regulation of transcription from an RNA polymerase II promoter					This term was obsoleted because it represents a GO-CAM model.		mah	2010-11-16T03:08:25Z		True			biological_process											owl:Class	
GO:0003802	biolink:NamedThing	obsolete coagulation factor VIIa activity	OBSOLETE. Catalysis of the selective cleavage of one Arg-Ile bond in factor X to form factor Xa, and on factor IX to form factor IXa beta.	tmpzr1t_l9r_go_relaxed.owl	blood-coagulation factor VIIa|blood coagulation factor VII activity|coagulation factor VIIa activity|activated blood coagulation factor VII			GO:0004252		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0072500	biolink:NamedThing	obsolete negative regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor	OBSOLETE. Any process in which a ligand-bound hormone receptor acts in the nucleus to stop, prevent, or reduce the frequency, rate or extent of transcription from an RNA polymerase II promoter.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor					This term was made obsolete because it is unclear whether the term represents the action of the receptor or the entire process of transcription regulation. The term 'nuclear hormone receptor' is also misleading since many of these receptors reside in the cytoplasm until they are bound by a ligand.	GO:0030522|GO:0004879|GO:0000122|GO:0030374	mah	2010-12-16T11:47:39Z		True			biological_process											owl:Class	
GO:0075159	biolink:NamedThing	obsolete regulation of G-protein alpha subunit-mediated signal transduction in response to host	OBSOLETE. Any process in which the symbiont organism modulates the frequency, rate or extent of its G-protein alpha subunit-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	regulation of symbiont G-protein alpha subunit-mediated signal transduction in response to host					This term was obsoleted because there is no evidence that this process exists.					True			biological_process											owl:Class	
GO:0106188	biolink:NamedThing	obsolete translocase activity acting on hydrons linked the hydrolysis of a nucleoside triphosphate	OBSOLETE. Catalysis of the translocation of hydrons linked to the hydrolysis of a nucleoside triphosphate.	tmpzr1t_l9r_go_relaxed.owl					EC:7.1.2.-	This term was made obsolete because the concept of using the non-4 digit EC classes as parent terms for the transporter banch of the onotolgy was consided confusing.		hjd	2019-05-07T18:09:07Z		True			molecular_function											owl:Class	
GO:0075148	biolink:NamedThing	obsolete positive regulation of signal transduction in response to host	OBSOLETE. Any process in which the symbiont organism activates, maintains or increases the frequency, rate or extent of its signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of symbiont signal transduction in response to host					This term was obsoleted because there is no evidence that this process exists.					True			biological_process											owl:Class	
GO:1900203	biolink:NamedThing	obsolete positive regulation of spread of virus in host, cell to cell	OBSOLETE. Any process that activates or increases the frequency, rate or extent of spread of virus in host, cell to cell.	tmpzr1t_l9r_go_relaxed.owl	activation of viral spread within host, cell to cell|activation of cell to cell spread of virus within host|upregulation of spread of virus in host, cell to cell|upregulation of viral spread within host, cell to cell|upregulation of cell to cell spread of virus within host|positive regulation of spread of virus in host, cell to cell|up regulation of cell to cell spread of virus within host|up-regulation of spread of virus in host, cell to cell|upregulation of spread of virus within host, cell to cell|up regulation of spread of virus in host, cell to cell|up regulation of spread of virus within host, cell to cell|positive regulation of viral spread within host, cell to cell|positive regulation of cell to cell spread of virus within host|up regulation of viral spread within host, cell to cell|up-regulation of viral spread within host, cell to cell|up-regulation of spread of virus within host, cell to cell|up-regulation of cell to cell spread of virus within host|activation of spread of virus within host, cell to cell|positive regulation of spread of virus within host, cell to cell|activation of spread of virus in host, cell to cell					This term was obsoleted at the TermGenie Gatekeeper stage.		pm	2012-03-21T01:16:00Z		True			biological_process											owl:Class	
GO:1902002	biolink:NamedThing	obsolete protein phosphorylation involved in cellular protein catabolic process	OBSOLETE. Any protein phosphorylation that is involved in cellular protein catabolic process.	tmpzr1t_l9r_go_relaxed.owl	protein phosphorylation involved in cellular protein catabolism|protein amino acid phosphorylation involved in cellular protein breakdown|protein amino acid phosphorylation involved in cellular protein catabolism|protein phosphorylation involved in cellular protein breakdown|protein phosphorylation involved in cellular protein degradation|protein amino acid phosphorylation involved in cellular protein degradation|protein amino acid phosphorylation involved in cellular protein catabolic process	https://github.com/geneontology/go-ontology/issues/14137				This term has been obsoleted because it represents a GO-CAM model.		pr	2013-03-21T10:08:19Z		True			biological_process											owl:Class	
GO:0072484	biolink:NamedThing	obsolete detection of stimulus involved in spindle assembly checkpoint	OBSOLETE. The series of events in which information about spindle assembly is received and converted into a molecular signal, contributing to a spindle assembly checkpoint.	tmpzr1t_l9r_go_relaxed.owl	spindle assembly checkpoint sensor mechanism|spindle assembly checkpoint sensor process|sensing involved in spindle assembly checkpoint	https://github.com/geneontology/go-ontology/issues/20976				This term was obsoleted because it corresponds to a molecular function.		mah	2010-12-09T12:19:16Z		True			biological_process											owl:Class	
GO:1901489	biolink:NamedThing	obsolete positive regulation of SREBP signaling pathway by negative regulation of transcription factor catabolic process in response to decreased oxygen levels	OBSOLETE. Negative regulation of transcription factor catabolism in response to decreased oxygen levels, which results in positive regulation of the SREBP signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of SREBP signaling by negative regulation of transcription factor catabolism at low oxygen levels|positive regulation of SREBP signaling pathway by negative regulation of SREBP degradation, in response to decreased oxygen|positive regulation of SREBP signaling by inhibition of SREBP degradation in response to decreased oxygen levels|positive regulation of SREBP-mediated signaling pathway in response to decreased oxygen levels by negative regulation of transcription factor catabolic process|positive regulation of SREBP-mediated signaling pathway in absence of oxygen by negative regulation of transcription factor catabolic process					The reason for obsoletion is that this term should be represented by a GO-CAM model.		bf	2012-10-09T08:23:50Z		True			biological_process											owl:Class	
GO:0004206	biolink:NamedThing	obsolete caspase-10 activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	caspase-10 activity			GO:0004197		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0016313	biolink:NamedThing	obsolete inositol-1,4,5-trisphosphate phosphatase	OBSOLETE. The removal of one of the phosphate groups from an inositol triphosphate to produce an inositol bisphosphate.	tmpzr1t_l9r_go_relaxed.owl	inositol-1,4,5-trisphosphate phosphatase					This term was made obsolete because it is a redundant grouping term with only one child.	GO:0046030				True			molecular_function											owl:Class	
GO:0039712	biolink:NamedThing	obsolete induction by virus of host catalytic activity	OBSOLETE. Any viral process that activates or increases the frequency, rate or extent of host catalytic activity.	tmpzr1t_l9r_go_relaxed.owl	induction by virus of host enzyme activity	https://github.com/geneontology/go-ontology/issues/21740				This term was obsoleted because it represents a molecular function.		bf	2013-12-19T13:21:45Z		True			biological_process											owl:Class	
GO:0042099	biolink:NamedThing	obsolete gamma-delta T cell receptor activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	gamma-delta T cell receptor activity					This term was made obsolete because it describes a receptor type, and not an activity.	GO:0032394|GO:0032395|GO:0042605				True			molecular_function											owl:Class	
GO:0042031	biolink:NamedThing	obsolete angiotensin-converting enzyme inhibitor activity	OBSOLETE. Stops, prevents or reduces the activity of angiotensin-converting enzyme, thereby preventing the synthesis of angiotensin II from its precursor, angiotensin I.	tmpzr1t_l9r_go_relaxed.owl	peptidyl dipeptidase A inhibitor|angiotensin-converting enzyme inhibitor activity|ACE inhibitor			GO:0060422		This term was made obsolete because it represents a regulator of a non-existent molecular function term.					True			molecular_function											owl:Class	
GO:0052429	biolink:NamedThing	obsolete modulation by organism of symbiont B-cell mediated immune response	OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of the B-cell mediated immune response of a symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	regulation by organism of symbiont B-cell mediated immune response|modulation by organism of symbiont B-cell mediated immune response					This term was made obsolete because it does not represent a real biological process.					True			biological_process											owl:Class	
GO:0042624	biolink:NamedThing	obsolete ATPase activity, uncoupled	OBSOLETE. Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction is not directly coupled to any other reaction.	tmpzr1t_l9r_go_relaxed.owl						The reason for obsoletion is that the there is no convincing example of a protein with this function.					True			molecular_function											owl:Class	
GO:0045871	biolink:NamedThing	obsolete negative regulation of rhodopsin gene expression	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of rhodopsin gene expression.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of rhodopsin gene activity|inhibition of rhodopsin gene activity|down-regulation of rhodopsin gene activity|down regulation of rhodopsin gene activity|downregulation of rhodopsin gene activity					This term was obsoleted because it referes to a specific gene product. The gene product should be captured as an annotation extension using 'has input'.	GO:0000122				True			biological_process											owl:Class	
GO:1903134	biolink:NamedThing	obsolete trehalose catabolic process involved in cellular response to stress	OBSOLETE. Any trehalose catabolic process that is involved in cellular response to stress.	tmpzr1t_l9r_go_relaxed.owl	trehalose breakdown involved in cellular response to stress|trehalose catabolism involved in cellular response to stress|mycose catabolic process involved in cellular response to stress|mycose catabolism involved in cellular response to stress|mykose catabolic process involved in cellular response to stress|trehalose degradation involved in cellular response to stress|mykose catabolism involved in cellular response to stress	https://github.com/geneontology/go-ontology/issues/18200				This term was obsoleted because it does not represent a specific pathway.		al	2014-06-25T22:28:34Z		True			biological_process											owl:Class	
GO:0031276	biolink:NamedThing	obsolete negative regulation of lateral pseudopodium assembly	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the assembly of pseudopodia from the lateral side of the cell.	tmpzr1t_l9r_go_relaxed.owl	downregulation of lateral pseudopodium formation|down regulation of lateral pseudopodium formation|negative regulation of lateral pseudopodium formation|inhibition of lateral pseudopodium formation|down-regulation of lateral pseudopodium formation	https://github.com/geneontology/go-ontology/issues/21738		GO:0120320		The regulation of lateral pseudopodium assembly terms were not used consistently. The negative regulation term has been replaced by GO:0120320 lateral pseudopodium retraction.					True			biological_process											owl:Class	
GO:1990921	biolink:NamedThing	obsolete proteasome localization to nuclear periphery	OBSOLETE. A process in which a proteasome is transported to, or maintained in, a location within the nuclear periphery.	tmpzr1t_l9r_go_relaxed.owl	proteasome localisation to nuclear periphery					This term was obsoleted at the TermGenie Gatekeeper stage.		mah	2015-12-15T12:02:31Z		True			biological_process											owl:Class	
GO:0008008	biolink:NamedThing	obsolete membrane attack complex protein beta2 chain	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	membrane attack complex protein beta2 chain			GO:0005579		This term was made obsolete because it represents a single gene product and not a complex.					True			cellular_component											owl:Class	
GO:0016916	biolink:NamedThing	obsolete inhibin	OBSOLETE. Either of two glycoproteins (designated A and B), secreted by the gonads and present in seminal plasma and follicular fluid, that inhibit pituitary production of follicle-stimulating hormone.	tmpzr1t_l9r_go_relaxed.owl	inhibin					This term was made obsolete because it represents a gene product.	GO:0046882|GO:0005160				True			molecular_function											owl:Class	
GO:0015253	biolink:NamedThing	obsolete sugar/polyol channel activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	sugar/polyol channel activity					This term was made obsolete because it represents two molecular functions.	GO:0051119|GO:0015166				True			molecular_function											owl:Class	
GO:0101007	biolink:NamedThing	obsolete negative regulation of transcription from RNA polymerase II promoter in response to salt stress	OBSOLETE. Any process that decreases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is under salt stress. The stress is usually an increase or decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/12739				This term was obsoleted because it represents a GO-CAM model.	GO:0000122|GO:0071472	mec			True			biological_process											owl:Class	
GO:0000059	biolink:NamedThing	obsolete protein import into nucleus, docking	OBSOLETE. A protein complex assembly process that contributes to protein import into the nucleus, and that results in the association of a cargo protein, a carrier protein such as an importin alpha/beta heterodimer, and a nucleoporin located at the periphery of the nuclear pore complex.	tmpzr1t_l9r_go_relaxed.owl	protein-nucleus import, docking|protein docking during protein import into nucleus|protein transport from cytoplasm to nucleus, docking|protein docking during protein transport from cytoplasm to nucleus|protein docking during protein-nucleus import					This term was made obsolete because the transient assembly is better captured as a protein-protein association, if at all.					True			biological_process											owl:Class	
GO:0052450	biolink:NamedThing	obsolete modulation by organism of induced systemic resistance in symbiont	OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of induced systemic resistance in the symbiont organism; induced systemic resistance is a response that confers broad spectrum systemic resistance to disease and that does not depend upon salicylic acid signaling. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	modulation by organism of induced systemic resistance in symbiont					This term was made obsolete because it does not represent a real biological process.					True			biological_process											owl:Class	
GO:0045750	biolink:NamedThing	obsolete positive regulation of S phase of mitotic cell cycle	OBSOLETE. Any process that activates or increases the frequency, rate or extent of S phase of mitotic cell cycle activity.	tmpzr1t_l9r_go_relaxed.owl	activation of S phase of mitotic cell cycle|up regulation of S phase of mitotic cell cycle|positive regulation of S-phase of mitotic cell cycle|positive regulation of S phase of mitotic cell cycle|stimulation of S phase of mitotic cell cycle|upregulation of S phase of mitotic cell cycle|up-regulation of S phase of mitotic cell cycle					This term was made obsolete as part of the cell cycle overhaul. This is because it was decided that cell cycle phases are intervals and so cannot be regulated, rather it is the transitions between the phases that are regulated.					True			biological_process											owl:Class	
GO:0008991	biolink:NamedThing	obsolete serine-type signal peptidase activity	OBSOLETE. Catalysis of the cleavage of a signal peptide from a protein precursor by a serine endopeptidase mechanism.	tmpzr1t_l9r_go_relaxed.owl	serine-type signal peptidase activity			GO:0004252		This term was made obsolete because 'signal peptide' is difficult to define unambiguously, and because the term refers to gene products.					True			molecular_function											owl:Class	
GO:0006733	biolink:NamedThing	obsolete oxidoreduction coenzyme metabolic process	OBSOLETE. The chemical reactions and pathways involving coenzymes that are required, in addition to an enzyme and a substrate, for an oxidoreductase reaction to proceed.	tmpzr1t_l9r_go_relaxed.owl	oxidoreduction coenzyme metabolism					1. Making inferences in GO about compounds based on the coenzyme role curated by ChEBI creates relationships that are not always true which violates ontological principles for GO; therefore we will cease making these inferences. 2. It is not meaningful to group metabolic processes that are not all metabolically related by the fact that they may be used as a coenzyme.					True			biological_process											owl:Class	
GO:1902399	biolink:NamedThing	obsolete detection of stimulus involved in G1 DNA damage checkpoint	OBSOLETE. Any detection of stimulus that is involved in G1 DNA damage checkpoint.	tmpzr1t_l9r_go_relaxed.owl	stimulus detection involved in G1/S DNA damage checkpoint|stimulus sensing involved in G1/S DNA damage checkpoint|stimulus detection involved in G1 DNA damage checkpoint|perception of stimulus involved in G1/S DNA damage checkpoint|detection of stimulus involved in G1/S DNA damage checkpoint|stimulus sensing involved in G1 DNA damage checkpoint|perception of stimulus involved in G1 DNA damage checkpoint	https://github.com/geneontology/go-ontology/issues/20976				This term was obsoleted because it corresponds to a molecular function.		jl	2013-09-12T12:01:49Z		True			biological_process											owl:Class	
GO:0044008	biolink:NamedThing	obsolete dissemination or transmission of symbiont from host by vector	OBSOLETE. The movement of an organism from one host to another (or another place in the environment) by means of a third organism (often an insect or other animal). The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	dissemination or transmission of organism from host by vector					This term was obsoleted because it did not represent a specific process, but represented the life cycle of a symbiont.					True			biological_process											owl:Class	
GO:0052115	biolink:NamedThing	obsolete energy taxis in host environment	OBSOLETE. The directed movement of a motile cell or organism in the environment of its host organism in response to physical parameters involved in energy generation, such as light, oxygen, and oxidizable substrates. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	energy taxis in response to host environment					This term was obsoleted because it represents both a process and a location.					True			biological_process											owl:Class	
GO:0052487	biolink:NamedThing	obsolete negative regulation by organism of symbiont jasmonic acid-mediated defense response	OBSOLETE. Any process by which an organism stops, prevents, or reduces the frequency, rate or extent of the jasmonic acid-mediated defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	suppression by organism of symbiont JA-mediated defense response|negative regulation by organism of symbiont jasmonic acid-mediated defense response					This term was made obsolete because it does not represent a real biological process.					True			biological_process											owl:Class	
GO:0045189	biolink:NamedThing	obsolete connective tissue growth factor biosynthetic process	OBSOLETE. The chemical reactions and pathways resulting in the formation of CTGF, produced by human umbilical vein endothelial cells and by skin fibroblasts after activation with TGF-beta.	tmpzr1t_l9r_go_relaxed.owl	connective tissue growth factor formation|connective tissue growth factor synthesis|connective tissue growth factor anabolism|CTGF biosynthesis|connective tissue growth factor biosynthesis					This term was obsoleted because it represent translation of a gene product, not a specific process.					True			biological_process											owl:Class	
GO:0000047	biolink:NamedThing	obsolete Rieske iron-sulfur protein	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	Rieske iron-sulphur protein|Rieske iron-sulfur protein					This term was made obsolete because it represents a gene product.	GO:0009055				True			molecular_function											owl:Class	
GO:1903162	biolink:NamedThing	obsolete serine transmembrane transporter activity involved in serine import into cell	OBSOLETE. Any serine transmembrane transporter activity that is involved in serine import into cell.	tmpzr1t_l9r_go_relaxed.owl	serine transmembrane transporter activity involved in serine import into cell					This term was obsoleted at the TermGenie Gatekeeper stage.		dos	2014-07-09T11:56:44Z		True			molecular_function											owl:Class	
GO:0008943	biolink:NamedThing	obsolete glyceraldehyde-3-phosphate dehydrogenase activity	OBSOLETE. Catalysis of the reactions: glyceraldehyde 3-phosphate + phosphate + NAD(P)+ = 3-phospho-D-glyceroyl-phosphate + NAD(P)H + H+, and glyceraldehyde 3-phosphate + H2O + NAD(P)+ = 3-phospho-D-glycerate + NAD(P)H + H+.	tmpzr1t_l9r_go_relaxed.owl	glyceraldehyde-3-phosphate dehydrogenase activity					This term was made obsolete because it is a grouping term based on similar names.	GO:0047100|GO:0043878|GO:0008886|GO:0004365				True			molecular_function											owl:Class	
GO:0016739	biolink:NamedThing	obsolete oxidoreductase activity, acting on other substrates	OBSOLETE. A grouping term for oxidoreductase that cannot be more accurately categorized.	tmpzr1t_l9r_go_relaxed.owl	oxidoreductase activity, acting on other substrates					This term was made obsolete because it was an unnecessary grouping term.	GO:0016491				True			molecular_function											owl:Class	
GO:0038075	biolink:NamedThing	obsolete MAP kinase activity involved in innate immune response	OBSOLETE. Catalysis of the reaction: protein + ATP = protein phosphate + ADP by a mitogen-activated protein kinase, as part of a MAPK signaling cascade that contributes to an innate immune response.	tmpzr1t_l9r_go_relaxed.owl	MAPK activity involved in innate immune response	https://github.com/geneontology/go-ontology/issues/18000				This term was obsoleted because it should be represented as a GO-CAM model.		bf	2012-01-26T02:35:52Z		True			molecular_function											owl:Class	
GO:0007573	biolink:NamedThing	obsolete age dependent increased protein content	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	age dependent increased protein content					This term was made obsolete because it does not describe a biological process.	GO:0007571				True			biological_process											owl:Class	
GO:0030567	biolink:NamedThing	obsolete thrombin activator activity	OBSOLETE. Increases the rate of proteolysis catalyzed by thrombin.	tmpzr1t_l9r_go_relaxed.owl	prothrombin activator activity|thrombin activator activity			GO:0016504		This term was made obsolete because it represents a regulator of an obsolete molecular function.					True			molecular_function											owl:Class	
GO:0052100	biolink:NamedThing	obsolete intraspecies quorum sensing	OBSOLETE. The process in which single-celled organisms of the same species monitor population density by detecting the concentration of small, diffusible signal molecules.	tmpzr1t_l9r_go_relaxed.owl						The reason for obsoletion is that this term was an unnecessary grouping term.					True			biological_process											owl:Class	
GO:0009470	biolink:NamedThing	obsolete class IIa cytochrome c	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	class IIa cytochrome c					This term was made obsolete because it represents a gene product.	GO:0009055				True			molecular_function											owl:Class	
GO:0075089	biolink:NamedThing	obsolete negative regulation by host of symbiont G protein-coupled receptor signal transduction	OBSOLETE. Any process in which the host organism stops, prevents, or reduces the frequency, rate or extent of the symbiont G protein-coupled receptor signal transduction. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	negative regulation by host of symbiont G-protein coupled receptor protein signal transduction					The reason for obsoletion is that there is no evidence that the host can modulate or regulate a symbiont's signal transduction pathway.					True			biological_process											owl:Class	
GO:0051194	biolink:NamedThing	obsolete positive regulation of cofactor metabolic process	OBSOLETE. Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a cofactor.	tmpzr1t_l9r_go_relaxed.owl	up regulation of cofactor metabolic process|stimulation of cofactor metabolic process|up-regulation of cofactor metabolic process|activation of cofactor metabolic process|upregulation of cofactor metabolic process|positive regulation of cofactor metabolism					1. Making inferences in GO about compounds based on the cofactor role curated by ChEBI creates relationships that are not always true which violates ontological principles for GO; therefore we will cease making these inferences. 2. It is not meaningful to group metabolic processes that are not all chemically related by the fact that they may be used as a cofactor.					True			biological_process											owl:Class	
GO:0060969	biolink:NamedThing	obsolete negative regulation of gene silencing	OBSOLETE. Any process that decreases the rate, frequency, or extent of gene silencing, the transcriptional or post-transcriptional process carried out at the cellular level that results in long-term gene inactivation.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/22202				This term was obsoleted because its definition was too broad.	GO:0031047|GO:0010629|GO:0031507	dph	2009-10-05T03:26:19Z		True			biological_process											owl:Class	
GO:0052241	biolink:NamedThing	obsolete positive chemotaxis on or near other organism involved in symbiotic interaction	OBSOLETE. The directed movement of a motile cell or organism towards a higher concentration of a specific chemical on or near a second organism, where the two organisms are in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	positive chemotaxis on or near other organism during symbiotic interaction	https://github.com/geneontology/go-ontology/issues/18819				This term was obsoleted because it represents both a process and a location.					True			biological_process											owl:Class	
GO:0085040	biolink:NamedThing	obsolete extra-invasive hyphal space	OBSOLETE. The space between the symbiont plasma membrane and the extra-invasive hyphal membrane.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/19013				This term was obsoleted because the cellular component represented is not different from 'host cytoplasm'.		jl	2010-07-27T04:21:26Z		True			cellular_component											owl:Class	
GO:0003793	biolink:NamedThing	obsolete defense/immunity protein activity	OBSOLETE. Any activity that plays a role in the defense/immune response of an organism against infection and disease.	tmpzr1t_l9r_go_relaxed.owl	defence/immunity protein activity|defense/immunity protein activity					This term was made obsolete because it refers to involvement in a biological process.	GO:0006952				True			molecular_function											owl:Class	
GO:0052473	biolink:NamedThing	obsolete negative regulation by organism of symbiont B-cell mediated immune response	OBSOLETE. Any process by which an organism stops, prevents, or reduces the frequency, rate or extent of the B-cell mediated immune response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	negative regulation by organism of symbiont B-cell mediated immune response					This term was made obsolete because it does not represent a real biological process.					True			biological_process											owl:Class	
GO:1905249	biolink:NamedThing	obsolete negative regulation of memory	OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of memory.	tmpzr1t_l9r_go_relaxed.owl	inhibition of memory|suppression of memory					This term was obsoleted at the TermGenie Gatekeeper stage.		ha	2016-06-09T13:54:45Z		True			biological_process											owl:Class	
GO:0043581	biolink:NamedThing	obsolete mycelium development	OBSOLETE. The process whose specific outcome is the progression of the mycelium over time, from its formation to the mature structure. A mycelium consists of a mass of branching, thread-like hyphae.	tmpzr1t_l9r_go_relaxed.owl						The reason for obsoletion is that the term is ambiguous. Three more clearly defined terms have been created that should be considered in its place.	GO:0097737|GO:0097738|GO:0097736				True			biological_process											owl:Class	
GO:0005924	biolink:NamedThing	obsolete cell-substrate adherens junction	OBSOLETE. An adherens junction which connects a cell to the extracellular matrix.	tmpzr1t_l9r_go_relaxed.owl	hemi-adherens junction					The reason for obsoletion is that, based on the most recent literature, there is no such structure in biology as 'cell-substrate adherens junction'. An 'adherens junction' is always a 'cell-cell junction' (PMIDs: 20571587, 17854762, 21422226, 28096264, 28401269, 26923917).					True			cellular_component											owl:Class	
GO:0075162	biolink:NamedThing	obsolete regulation of G-protein beta subunit-mediated signal transduction in response to host	OBSOLETE. Any process in which the symbiont organism modulates the frequency, rate or extent of its G-protein beta subunit-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	regulation of symbiont G-protein beta subunit-mediated signal transduction in response to host					This term was obsoleted because there is no evidence that this process exists.					True			biological_process											owl:Class	
GO:0071537	biolink:NamedThing	obsolete C3HC4-type RING finger domain-mediated complex assembly	OBSOLETE. A process of protein complex assembly in which the arrangement and bonding together of the set of components that form the protein complex is mediated by a C3HC4-type RING finger domain interaction.	tmpzr1t_l9r_go_relaxed.owl	zinc finger C3HC4 type domain-mediated complex assembly					This term was obsoleted because it represented a molecular function (binding), not a biological process.  The term represented a domain involved in protein-protein interactions, but no necessarily the process of assembling a complex.		mah	2010-01-08T03:42:46Z		True			biological_process											owl:Class	
GO:0016347	biolink:NamedThing	obsolete calcium-independent cell adhesion molecule activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	calcium-independent cell adhesion molecule activity					This term was made obsolete because it represents a gene product.	GO:0005515|GO:0007161|GO:0016021|GO:0016338				True			molecular_function											owl:Class	
GO:0001577	biolink:NamedThing	obsolete galectin	OBSOLETE. A lectin that exhibits calcium independent binding of beta-galactoside sugars.	tmpzr1t_l9r_go_relaxed.owl	galectin|S-type lectin					This term was made obsolete because it refers to a class of gene products.	GO:0016936|GO:0007157				True			molecular_function											owl:Class	
GO:0005949	biolink:NamedThing	obsolete aminoadipate-semialdehyde dehydrogenase complex	OBSOLETE. A heterodimeric enzyme composed of an alpha and beta subunit. Catalyzes the formation of L-2-aminoadipate from L-2-aminoadipate 6-semialdehyde.	tmpzr1t_l9r_go_relaxed.owl	aminoadipate-semialdehyde dehydrogenase complex					This term was made obsolete because the catalytic activity resides in a single polypeptide that is not part of a complex with other gene products.					True			cellular_component											owl:Class	
GO:0008322	biolink:NamedThing	obsolete Pro-X carboxypeptidase activity	OBSOLETE. Catalysis of the cleavage of a Pro-Xaa bond to release a C-terminal amino acid.	tmpzr1t_l9r_go_relaxed.owl	Pro-X carboxypeptidase activity			GO:0030536		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0030618	biolink:NamedThing	obsolete transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity	OBSOLETE. A TGF-beta cytoplasmic mediator that is phosphorylated by a TGFbeta receptor and complexes with a common-partner mediator. The- heterocomplex translocates to the nucleus to regulate transcription.	tmpzr1t_l9r_go_relaxed.owl	receptor regulated SMAD protein|pathway restricted SMAD protein|pathway-specific SMAD protein|receptor-regulated SMAD protein|TGFbeta receptor, pathway-specific cytoplasmic mediator activity|TGF-beta receptor, pathway-specific cytoplasmic mediator activity|pathway-restricted SMAD protein	https://github.com/geneontology/go-ontology/issues/16202				This term was obsoleted because it is redundant with other terms.	GO:0000981|GO:0003712				True			molecular_function											owl:Class	
GO:0015053	biolink:NamedThing	obsolete opsin	OBSOLETE. Hydrophobic glycoprotein to which 11-cis-retinal binds as a Schiff base (in rhodopsin) or 3,4-didehydro-11-cis-retinal binds as a Schiff base in cyanopsin and porphyropsin.	tmpzr1t_l9r_go_relaxed.owl	opsin					This term was made obsolete because it refers to a class of proteins.	GO:0016021|GO:0009881|GO:0016918|GO:0046876|GO:0007602				True			molecular_function											owl:Class	
GO:0006224	biolink:NamedThing	obsolete uridine kinase reaction	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	uridine kinase reaction			GO:0004849		This term was made obsolete because it represents a molecular function.					True			biological_process											owl:Class	
GO:2000574	biolink:NamedThing	obsolete regulation of microtubule motor activity	OBSOLETE. Any process that modulates the frequency, rate or extent of microtubule motor activity.	tmpzr1t_l9r_go_relaxed.owl	regulation of kinesin motor activity|regulation of axonemal motor activity|regulation of kinetochore motor activity|regulation of kinesin|regulation of dynein ATPase activity|regulation of dynein	https://github.com/geneontology/go-ontology/issues/21626				This term was obsoleted because it represents a molecular function.	GO:0140659	bf	2011-04-05T08:36:44Z		True			biological_process											owl:Class	
GO:0030440	biolink:NamedThing	obsolete activation of MAPKK during sporulation (sensu Fungi)	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	activation of MAPKK during sporulation (sensu Fungi)					This term was made obsolete because it is a gene product specific term.					True			biological_process											owl:Class	
GO:0033547	biolink:NamedThing	obsolete myo-inositol hexakisphosphate biosynthetic process, via direct phosphorylation of inositol 1,4,5-trisphosphate	OBSOLETE. The chemical reactions and pathways resulting in the formation of 1D myo-inositol 1,2,3,4,5,6-hexakisphosphate, phytate, by a pathway using inositol 1,4,5-trisphosphate produced from phosphatidylinositol 4,5-biphosphate hydrolysis by phospholipase C; in this pathway, inositol 1,4,5-trisphosphate is successively phosphorylated to yield inositol hexakisphosphate.	tmpzr1t_l9r_go_relaxed.owl	myo-inositol hexakisphosphate formation, via direct phosphorylation of inositol 1,4,5-trisphosphate|myo-inositol hexakisphosphate biosynthesis, via direct phosphorylation of inositol 1,4,5-trisphosphate|myo-inositol hexakisphosphate biosynthetic process, via direct phosphorylation of inositol 1,4,5-trisphosphate|phytate biosynthesis, via direct phosphorylation of inositol 1,4,5-trisphosphate|myo-inositol hexakisphosphate anabolism, via direct phosphorylation of inositol 1,4,5-trisphosphate|phytate biosynthetic process, via direct phosphorylation of inositol 1,4,5-trisphosphate|myo-inositol hexakisphosphate synthesis, via direct phosphorylation of inositol 1,4,5-trisphosphate				MetaCyc:PWY-4541	This term was made obsolete because its only cross-reference points to a MetaCyc entry (PWY-4541) that was deleted from the MetaCyc database.					True			biological_process											owl:Class	
GO:0044151	biolink:NamedThing	obsolete growth of host on or near symbiont surface	OBSOLETE. The increase in size or mass of an organism occurring on or near the exterior of its symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	growth of organism on or near symbiont surface	https://github.com/geneontology/go-ontology/issues/18786				This term was obsoleted because it represents both a process and a location.		jl	2009-08-06T03:16:19Z		True			biological_process											owl:Class	
GO:0008125	biolink:NamedThing	obsolete pancreatic elastase I activity	OBSOLETE. Catalysis of the hydrolysis of proteins, including elastin. Preferential cleavage: Ala-Xaa.	tmpzr1t_l9r_go_relaxed.owl	serine elastase|elaszym|pancreatopeptidase E activity|pancreatic elastase I activity			GO:0004252		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:1904773	biolink:NamedThing	obsolete cellular response to tetrachloromethane	OBSOLETE. Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tetrachloromethane stimulus.	tmpzr1t_l9r_go_relaxed.owl	cellular response to CCL4|cellular response to carbon tetrachloride					This term was obsoleted at the TermGenie Gatekeeper stage.		sl	2015-10-28T20:59:21Z		True			biological_process											owl:Class	
GO:1904532	biolink:NamedThing	obsolete ATP-dependent microtubule motor activity, minus-end-directed involved in microtubule-based movement	OBSOLETE. Any ATP-dependent microtubule motor activity, minus-end-directed that is involved in microtubule-based movement.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted at the TermGenie Gatekeeper stage.		vw	2015-07-31T06:45:48Z		True			molecular_function											owl:Class	
GO:1990985	biolink:NamedThing	obsolete apoptosis in response to oxidative stress	OBSOLETE. Any biological process that results in permanent cessation of all vital functions of a cell upon exposure to oxidative stress.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted at the TermGenie Gatekeeper stage.		pg	2016-11-17T14:12:17Z		True			biological_process											owl:Class	
GO:0075235	biolink:NamedThing	obsolete modulation of zoospore movement on or near host	OBSOLETE. Any process that modulates the frequency, rate or extent of zoospore movement on or near host. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	regulation of zoospore motility on or near host					This term was obsoleted because it represented both a process and a location.					True			biological_process											owl:Class	
GO:0030817	biolink:NamedThing	obsolete regulation of cAMP biosynthetic process	OBSOLETE. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate).	tmpzr1t_l9r_go_relaxed.owl	regulation of cyclic AMP biosynthetic process|regulation of 3',5' cAMP biosynthesis|regulation of cAMP formation|regulation of 3',5' cAMP biosynthetic process|regulation of 3',5'-cAMP biosynthesis|regulation of cyclic AMP biosynthesis|regulation of cAMP biosynthesis|regulation of cAMP anabolism|regulation of 3',5'-cAMP biosynthetic process|regulation of adenosine 3',5'-cyclophosphate biosynthetic process|regulation of adenosine 3',5'-cyclophosphate biosynthesis|regulation of cAMP synthesis	https://github.com/geneontology/go-ontology/issues/14718				This term was obsoleted because it represents a molecular function.					True			biological_process											owl:Class	
GO:0110144	biolink:NamedThing	obsolete magnetosome part	OBSOLETE. Any constituent part of a magnetosome, a membrane-bound organelle that envelops particles of magnetic iron minerals in magnetotactic bacteria.	tmpzr1t_l9r_go_relaxed.owl							GO:0110143	kmv	2019-05-30T17:36:02Z		True			cellular_component											owl:Class	
GO:0044052	biolink:NamedThing	obsolete interaction with host via substance released by membrane budding	OBSOLETE. An interaction with the host organism mediated by a substance released via symbiont membrane budding, the evagination of a membrane resulting in formation of a vesicle.	tmpzr1t_l9r_go_relaxed.owl	interaction with host via substance released by symbiont membrane budding					This term was obsoleted because it conflates a process and the mechanism of secretion of the gene product mediating the process.					True			biological_process											owl:Class	
GO:0045858	biolink:NamedThing	obsolete positive regulation of molecular function, epigenetic	OBSOLETE. Any heritable epigenetic process that increases the frequency, rate or extent of protein function by self-perpetuating conformational conversions of normal proteins in healthy cells. This is distinct from, though mechanistically analogous to, disease states associated with prion propagation and amyloidogenesis. A single protein, if it carries a glutamine/asparagine-rich ('prion') domain, can sometimes stably exist in at least two distinct physical states, each associated with a different phenotype; propagation of one of these traits is achieved by a self-perpetuating change in the protein from one form to the other, mediated by conformational changes in the glutamine/asparagine-rich domain. Prion domains are both modular and transferable to other proteins, on which they can confer a heritable epigenetic alteration of function; existing bioinformatics data indicate that they are rare in non-eukarya, but common in eukarya.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of protein activity, epigenetic|activation of protein activity, epigenetic|upregulation of protein activity, epigenetic|stimulation of protein activity, epigenetic|up regulation of protein activity, epigenetic|up-regulation of protein activity, epigenetic	https://github.com/geneontology/go-ontology/issues/22203				This term was obsoleted because it is not an active process.					True			biological_process											owl:Class	
GO:0006483	biolink:NamedThing	obsolete peptidyl-aspartic acid/asparagine hydroxylation	OBSOLETE. The hydroxylation of peptidyl-aspartic acid or asparagine.	tmpzr1t_l9r_go_relaxed.owl	peptidyl-aspartic acid/asparagine hydroxylation|aspartic acid/asparagine hydroxylation					This term was made obsolete because it is a redundant grouping term.	GO:0042265|GO:0042264				True			biological_process											owl:Class	
GO:0004218	biolink:NamedThing	obsolete cathepsin S activity	OBSOLETE. Catalysis of the hydrolysis of peptide bonds. Similar to cathepsin L, but with much less activity on the terminal bond of Z-Phe-Arg-NHMec, and more activity on the terminal bond of Z-Val-Val-Arg-Xaa compounds.	tmpzr1t_l9r_go_relaxed.owl	cathepsin S activity			GO:0004197		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0052455	biolink:NamedThing	obsolete modulation by organism of jasmonic acid levels in symbiont	OBSOLETE. The alteration by an organism of the levels of jasmonic acid in the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	modulation by organism of jasmonic acid levels in symbiont					This term was made obsolete because it does not represent a real biological process.					True			biological_process											owl:Class	
GO:0009614	biolink:NamedThing	obsolete disease resistance	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	disease resistance			GO:0051707		This term was made obsolete because 'resistance' implies a phenotype rather than a biological process.					True			biological_process											owl:Class	
GO:0005072	biolink:NamedThing	obsolete transforming growth factor beta receptor, cytoplasmic mediator activity	OBSOLETE. Activity of any of the molecules that transmit the signal from a TGF-beta receptor through the cytoplasm to the nucleus.	tmpzr1t_l9r_go_relaxed.owl	TGF-beta receptor, cytoplasmic mediator activity|TGFbeta receptor, cytoplasmic mediator activity	https://github.com/geneontology/go-ontology/issues/16202				This term was obsoleted because it is redundant with other terms.	GO:0000981				True			molecular_function											owl:Class	
GO:0044791	biolink:NamedThing	obsolete positive regulation by host of viral release from host cell	OBSOLETE. A process in which a host organism activates or increases the frequency, rate or extent of the release of a virus with which it is infected, from its cells.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/22168		GO:0019076		This term was obsoleted because there is no evidence that it is a regulated process.		jl	2013-06-06T10:51:48Z		True			biological_process											owl:Class	
GO:0001606	biolink:NamedThing	obsolete GPR37/endothelin B-like receptor activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	GPR37/endothelin B-like receptor activity					This term was made obsolete because it represents a gene product, was not defined, and is named based on protein features.					True			molecular_function											owl:Class	
GO:0031661	biolink:NamedThing	obsolete negative regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of cyclin-dependent protein serine/threonine kinase activity contributing to the G2/M transition of the cell cycle.	tmpzr1t_l9r_go_relaxed.owl	G2/M-specific inhibition of cyclin-dependent protein kinase activity|negative regulation of cyclin-dependent protein kinase activity involved in G2/M|G2/M-specific down regulation of cyclin-dependent protein kinase activity|negative regulation of cyclin-dependent protein kinase activity during G2/M|G2/M-specific down-regulation of cyclin-dependent protein kinase activity|G2/M-specific negative regulation of cyclin-dependent protein kinase activity|G2/M-specific downregulation of cyclin-dependent protein kinase activity					This term was obsoleted because it is a MF represented as a BP.	GO:0010389				True			biological_process											owl:Class	
GO:0000078	biolink:NamedThing	obsolete cytokinesis after mitosis checkpoint	OBSOLETE. A mitotic cell cycle checkpoint that detects whether chromosome segregation is complete and negatively regulates cytokinesis following mitosis.	tmpzr1t_l9r_go_relaxed.owl	cell shape checkpoint|cell morphogenesis checkpoint					The reason this term was made obsolete is that the two terms cytokinesis checkpoint (GO:0031565) and cytokinesis after mitosis (GO:0000078) were conflated in meaning.	GO:0044878|GO:0044879				True			biological_process											owl:Class	
GO:0031657	biolink:NamedThing	obsolete regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle	OBSOLETE. Any process that controls the frequency, rate or extent of G1 cyclin-dependent protein serine/threonine kinase activity contributing to the G1/S transition of the cell cycle.	tmpzr1t_l9r_go_relaxed.owl	G1/S-specific regulation of cyclin-dependent protein kinase activity|regulation of cyclin-dependent protein kinase activity involved in G1/S|regulation of cyclin-dependent protein kinase activity during G1/S					The term has been obsoleted because it represents a GO-CAM model.					True			biological_process											owl:Class	
GO:0044126	biolink:NamedThing	obsolete regulation of growth of symbiont in host	OBSOLETE. Any process in which the symbiont regulates the increase in its size or mass within the cells or tissues of the host organism. This may (but not necessarily) include a filamentous growth form, and also can include secretion of proteases and lipases to break down. The host is defined as the larger of the organisms involved in the symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it was partially redundant with other terms and its usage has been inconsistent.		jl	2009-08-04T02:10:08Z		True			biological_process											owl:Class	
RO:0002349	biolink:NamedThing	results in determination of		tmpzr1t_l9r_go_relaxed.owl					RO:0002349									external									results_in_determination_of			
GO:0039558	biolink:NamedThing	obsolete suppression by virus of host IRF7 activity by positive regulation of IRF7 sumoylation	OBSOLETE. Any process in which a virus stops, prevents, or reduces IRF7-dependent gene transcription, by promoting the sumoylation of IRF7, thereby disabling its activity.	tmpzr1t_l9r_go_relaxed.owl	suppression by virus of host interferon regulatory factor-7 activity by positive regulation of IRF7 sumoylation|promotion of IRF-7 SUMOylation					The reason for obsoleting is that the term is too specific. The exact molecular roles of the individual proteins should be captured separately.		bf	2012-03-09T04:27:57Z		True			biological_process											owl:Class	
GO:0008141	biolink:NamedThing	obsolete puparial glue (sensu Diptera)	OBSOLETE. A glue which attaches the pupae to the substrate during metamorphosis, as in, but not restricted to, the true flies (Diptera, ncbi_taxonomy_id:7147).	tmpzr1t_l9r_go_relaxed.owl	puparial glue (sensu Diptera)					This term was made obsolete because it represents a gene product and not a molecular function.	GO:0005198|GO:0007594				True			molecular_function											owl:Class	
GO:0005936	biolink:NamedThing	obsolete shmoo	OBSOLETE. The characteristic projection formed in response to mating pheromone by cells of Saccharomyces and other fungi with similar life cycles. Named after the Al Capp cartoon character, whose shape it resembles.	tmpzr1t_l9r_go_relaxed.owl	shmoo					This term was made obsolete because it represents a type of whole cell rather than a cellular component. To update annotations, consider the external ontology term 'shmoo ; FAO:0001023'.	GO:0001400|GO:0005937				True			cellular_component											owl:Class	
GO:0002120	biolink:NamedThing	obsolete predatory behavior	OBSOLETE. Aggressive behavior involving attack on prey by a predator.	tmpzr1t_l9r_go_relaxed.owl	predatory aggression|predatory aggressive behavior	https://github.com/geneontology/go-ontology/issues/18568				This term was obsoleted because it is outside the scope of GO.					True			biological_process											owl:Class	
GO:1902594	biolink:NamedThing	obsolete multi-organism nuclear import	OBSOLETE. A nuclear import which involves another organism.	tmpzr1t_l9r_go_relaxed.owl	multi organism nuclear import	https://github.com/geneontology/go-ontology/issues/21459				This term was obsoleted because there is no evidence that this process exists.		jl	2013-12-19T15:26:43Z		True			biological_process											owl:Class	
GO:0052228	biolink:NamedThing	obsolete metabolism by symbiont of host protein	OBSOLETE. The chemical reactions and pathways performed by an organism involving protein macromolecules within the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/21469				This term was obsoleted because it represents a molecular function.					True			biological_process											owl:Class	
GO:0003775	biolink:NamedThing	obsolete axonemal motor activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	axonemal motor activity					This term was made obsolete because it includes cellular component information.	GO:0003777|GO:0005930				True			molecular_function											owl:Class	
GO:0100049	biolink:NamedThing	obsolete negative regulation of phosphatidylcholine biosynthetic process by transcription from RNA polymerase II promoter	OBSOLETE. Any transcription from RNA polymerase II promoter process that negatively regulates phosphatidylcholine biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it represents a GO-CAM model.		cjm	2015-04-02T04:13:19Z		True			biological_process											owl:Class	
GO:0015468	biolink:NamedThing	obsolete colicin	OBSOLETE. Plasmid-encoded bacteriocins which are produced by enteric bacteria. Exert a lethal effect on other bacteria including E. coli strains that lack the Col plasmid. Bind to a cell surface receptor and are transported into the periplasm via an energy-dependent process involving a TonB- or TolA-dependent hetero-oligomeric protein complex. Some colicins kill their target cell by inserting into the cytoplasmic membrane where they form voltage-sensitive (trans-negative) channels that depolarize and deenergize the cell, and thereby kill it.	tmpzr1t_l9r_go_relaxed.owl	colicin					This term was made obsolete because it represents a class of gene products.	GO:0046931|GO:0005102|GO:0090729|GO:0019835|GO:0005198|GO:0046930				True			molecular_function											owl:Class	
GO:0042967	biolink:NamedThing	obsolete acyl-carrier-protein biosynthetic process	OBSOLETE. The chemical reactions and pathways resulting in the formation of acyl-carrier protein.	tmpzr1t_l9r_go_relaxed.owl	acyl-carrier-protein formation|acyl-carrier protein biosynthesis|ACP biosynthetic process|acyl carrier protein biosynthesis|acyl-carrier-protein anabolism|ACP biosynthesis|acyl carrier protein biosynthetic process|acyl-carrier-protein biosynthesis|acyl-carrier-protein synthesis					The reason for obsoletion is that acyl-carrier-protein is synthesized by the ribosome like any other protein.					True			biological_process											owl:Class	
GO:0016065	biolink:NamedThing	obsolete humoral defense mechanism (sensu Protostomia)	OBSOLETE. The specific immune response mediated by antibodies. As in, but not restricted to, the taxon Protostomia (Protostomia, ncbi_taxonomy_id:33317).	tmpzr1t_l9r_go_relaxed.owl	humoral defence mechanism (sensu Protostomia)|humoral defense mechanism (sensu Protostomia)					This term was made obsolete because antibodies are not found in the taxon Protostomia.					True			biological_process											owl:Class	
GO:0110132	biolink:NamedThing	obsolete regulation of CRISPR-cas system	OBSOLETE. Any process that modulates the frequency, rate or extent of a CRISPR-cas system.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/16423				This term was obsoleted because it does not accurately capture the process described in the literature.		kmv	2018-11-14T17:13:16Z		True			biological_process											owl:Class	
GO:1904080	biolink:NamedThing	obsolete positive regulation of transcription from RNA polymerase II promoter involved in neuron fate specification	OBSOLETE. Any positive regulation of transcription from RNA polymerase II promoter that is involved in neuron fate specification.	tmpzr1t_l9r_go_relaxed.owl	activation of transcription from RNA polymerase II promoter involved in neuron fate specification|upregulation of transcription from RNA polymerase II promoter involved in neuron fate specification|stimulation of global transcription from RNA polymerase II promoter involved in neuron fate specification|up-regulation of global transcription from RNA polymerase II promoter involved in neuron fate specification|positive regulation of transcription from Pol II promoter involved in neuron fate specification|positive regulation of gene-specific transcription from RNA polymerase II promoter involved in neuron fate specification|positive regulation of transcription from RNA polymerase II promoter, global involved in neuron fate specification|activation of global transcription from RNA polymerase II promoter involved in neuron fate specification|up regulation of transcription from RNA polymerase II promoter involved in neuron fate specification|positive regulation of global transcription from Pol II promoter involved in neuron fate specification|up regulation of global transcription from RNA polymerase II promoter involved in neuron fate specification|up-regulation of transcription from RNA polymerase II promoter involved in neuron fate specification|upregulation of global transcription from RNA polymerase II promoter involved in neuron fate specification|stimulation of transcription from RNA polymerase II promoter involved in neuron fate specification					This term was obsoleted because it represents a GO-CAM model.	GO:0045944|GO:0048665	kmv	2015-03-24T18:56:50Z		True			biological_process											owl:Class	
GO:0003733	biolink:NamedThing	obsolete ribonucleoprotein	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	ribonucleoprotein			GO:1990904		This term was made obsolete because it describes a cellular component rather than a molecular function.					True			molecular_function											owl:Class	
GO:2000153	biolink:NamedThing	obsolete regulation of flagellar cell motility	OBSOLETE. Any process that modulates the frequency, rate or extent of flagellar cell motility.	tmpzr1t_l9r_go_relaxed.owl	regulation of flagellar cell motility					This term was made obsolete because microtubule-based flagellum (GO:0009434) and motile cilium (GO:0031514), as referenced by this term, were determined to be equivalent and merged. When a merge for this term was considered, it was noticed that both eukaryotic and prokaryotic proteins are annotated to it because its meaning had been ambiguous so obsoletion was considered safest.	GO:1902021|GO:1902019	mah	2010-10-04T12:41:02Z		True			biological_process											owl:Class	
GO:1990824	biolink:NamedThing	obsolete magnesium-dependent protein complex	OBSOLETE. A protein complex that depends on magnesium in order for one or more of its components to remain a part of the complex.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted at the TermGenie Gatekeeper stage.		sl	2015-08-19T17:11:43Z		True			cellular_component											owl:Class	
GO:0005724	biolink:NamedThing	obsolete nuclear telomeric heterochromatin	OBSOLETE. Heterochromatic regions of the chromosome found at the telomeres of a chromosome in the nucleus.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/19086				This term was obsoleted because there is no heterochromatin at the telomere and the term had been used inconsistently.					True			cellular_component											owl:Class	
GO:0045891	biolink:NamedThing	obsolete negative regulation of transcription of homeotic gene (trithorax group)	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of transcription of homeotic genes of the trithorax group.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of transcription of homeotic gene (trithorax group)					This term was made obsolete because it relates to a specific gene family rather than a process.	GO:0000122				True			biological_process											owl:Class	
GO:0003900	biolink:NamedThing	obsolete DNA-directed RNA polymerase I activity	OBSOLETE. Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1).	tmpzr1t_l9r_go_relaxed.owl	DNA-directed RNA polymerase I activity			GO:0003899		This term was made obsolete because it represents the specific complex represented by the cellular component term 'DNA-directed RNA polymerase I complex ; GO:0005736'.					True			molecular_function											owl:Class	
GO:0016299	biolink:NamedThing	obsolete regulator of G-protein signaling activity	OBSOLETE. Inhibits signal transduction the GTPase activity of G-protein alpha subunits, thereby driving them into their inactive GDP-bound form.	tmpzr1t_l9r_go_relaxed.owl	regulator of G protein signaling activity|regulator of G-protein signaling activity|regulator of G-protein signalling activity|RGS|regulator of G protein signalling activity					This term was made obsolete because it refers to a combination of a function and a process.	GO:0034260|GO:0005095|GO:0045744				True			molecular_function											owl:Class	
GO:1902590	biolink:NamedThing	obsolete multi-organism organelle organization	OBSOLETE. An organelle organization which involves another organism.	tmpzr1t_l9r_go_relaxed.owl	multi organism organelle organization	https://github.com/geneontology/go-ontology/issues/21459				This term was obsoleted because there is no evidence that this process exists.		jl	2013-12-19T15:26:08Z		True			biological_process											owl:Class	
GO:0046560	biolink:NamedThing	obsolete scytalidopepsin B activity	OBSOLETE. Catalysis of the hydrolysis of proteins with broad specificity, cleaving Phe24-Phe, but not Leu15-Tyr and Phe25-Tyr in the B chain of insulin.	tmpzr1t_l9r_go_relaxed.owl	SLB|scytalidopepsin B activity|Scytalidium aspartic proteinase B activity|Ganoderma lucidum carboxyl proteinase activity|Scytalidium lignicolum aspartic proteinase B|Ganoderma lucidum aspartic proteinase activity			GO:0004190		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0044766	biolink:NamedThing	obsolete multi-organism transport	OBSOLETE. The directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or pore, involving more than one organism.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/21459				This term was obsoleted because there is no evidence that this process exists.		jl	2012-12-13T16:25:50Z		True			biological_process											owl:Class	
GO:0045473	biolink:NamedThing	obsolete response to ethanol (sensu Insecta)	OBSOLETE. A change in state or activity of an insect (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ethanol stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to ethanol (sensu Insecta)					This term was made obsolete because there is no clear difference between the sensu Insecta term and the generic term.	GO:0048149				True			biological_process											owl:Class	
GO:1990740	biolink:NamedThing	obsolete non-selective anion channel activity	OBSOLETE. Enables the non-selective, energy-independent passage of anions across a lipid bilayer down a concentration gradient.	tmpzr1t_l9r_go_relaxed.owl	nonselective anion channel activity					This term was made obsolete because it was added in error.		pr	2015-05-11T13:25:35Z		True			molecular_function											owl:Class	
GO:1900471	biolink:NamedThing	obsolete negative regulation of inositol biosynthetic process by negative regulation of transcription from RNA polymerase II promoter	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of inositol biosynthetic process by stopping, preventing, or reducing the frequency, rate or extent of transcription from an RNA polymerase II promoter.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of myo-inositol biosynthesis by negative regulation of transcription from RNA polymerase II promoter|negative regulation of inositol biosynthesis by negative regulation of transcription from RNA polymerase II promoter|negative regulation of inositol formation by negative regulation of transcription from RNA polymerase II promoter|negative regulation of inositol synthesis by negative regulation of transcription from RNA polymerase II promoter|negative regulation of vitamin Bh biosynthetic process by negative regulation of transcription from RNA polymerase II promoter|negative regulation of inositol anabolism by negative regulation of transcription from RNA polymerase II promoter|negative regulation of myo-inositol biosynthetic process by negative regulation of transcription from RNA polymerase II promoter|negative regulation of vitamin Bh biosynthesis by negative regulation of transcription from RNA polymerase II promoter					This term was obsoleted because it represents a GO-CAM model.		dgf	2012-05-01T08:13:23Z		True			biological_process											owl:Class	
GO:0052002	biolink:NamedThing	obsolete metabolism by symbiont of substance in host	OBSOLETE. The chemical reactions and pathways performed by an organism in its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/21469				This term was obsoleted because it represents a molecular function.					True			biological_process											owl:Class	
GO:0045094	biolink:NamedThing	obsolete interleukin-18 beta subunit binding	OBSOLETE. Binding to beta subunit of interleukin-18. IL-18b is a ligand non-binding chain and is required for signaling of IL-18 that binds with IL-18a.	tmpzr1t_l9r_go_relaxed.owl	IL-18Rb binding					This term was obsoleted because interleukin-18 is a single polypeptide and has no subunits.					True			molecular_function											owl:Class	
GO:0106197	biolink:NamedThing	obsolete translocase activity acting on inorganic anions linked to the hydrolysis of a diphosphate	OBSOLETE. Catalysis of the translocation of inorganic anions llinked to the hydrolysis of a diphosphate.	tmpzr1t_l9r_go_relaxed.owl					EC:7.3.3.-	This term was made obsolete because the concept of using the non-4 digit EC classes as parent terms for the transporter banch of the onotolgy was consided confusing.		hjd	2019-05-08T18:17:37Z		True			molecular_function											owl:Class	
GO:0100046	biolink:NamedThing	obsolete positive regulation of arginine biosynthetic process by transcription from RNA polymerase II promoter	OBSOLETE. Any transcription from RNA polymerase II promoter process that positively regulates arginine biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl						GO:0100046		cjm	2015-04-02T04:13:19Z		True			biological_process											owl:Class	
GO:0009464	biolink:NamedThing	obsolete cytochrome b5	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	cytochrome b5					This term was made obsolete because it represents a gene product.	GO:0009055				True			molecular_function											owl:Class	
GO:0016674	biolink:NamedThing	obsolete oxidoreductase activity, acting on sulfur group of donors, other acceptors	OBSOLETE. Catalysis of an oxidation-reduction (redox) reaction in which a sulfur-containing group acts as a hydrogen or electron donor and reduces an acceptor other than quinone or a related compound, oxygen, NAD, NADP, an iron-sulfur protein, disulfide or a cytochrome.	tmpzr1t_l9r_go_relaxed.owl	oxidoreductase activity, acting on sulphur group of donors, other acceptors|oxidoreductase activity, acting on sulfur group of donors, other acceptors					This term was made obsolete because it was an unnecessary grouping term.	GO:0016667				True			molecular_function											owl:Class	
GO:0035950	biolink:NamedThing	obsolete regulation of oligopeptide transport by regulation of transcription from RNA polymerase II promoter	OBSOLETE. Any process that modulates the frequency, rate or extent of oligopeptide transport, by regulation of transcription from an RNA polymerase II promoter.	tmpzr1t_l9r_go_relaxed.owl	regulation of oligopeptide transport by regulation of transcription from Pol II promoter					This term was obsoleted because it represents a GO-CAM model.		bf			True			biological_process											owl:Class	
GO:0016870	biolink:NamedThing	obsolete intramolecular transferase activity, transferring other groups	OBSOLETE. A grouping term for intramolecular transferases that cannot be more accurately categorized.	tmpzr1t_l9r_go_relaxed.owl	intramolecular transferase activity, transferring other groups					This term was made obsolete because it was an unnecessary grouping term.	GO:0016866				True			molecular_function											owl:Class	
GO:1900422	biolink:NamedThing	obsolete positive regulation of cellular alcohol catabolic process by positive regulation of transcription from RNA polymerase II promoter	OBSOLETE. A positive regulation of transcription from RNA polymerase II promoter that results in positive regulation of cellular alcohol catabolic process.	tmpzr1t_l9r_go_relaxed.owl	up regulation of cellular alcohol catabolic process by positive regulation of transcription from RNA polymerase II promoter|activation of cellular alcohol catabolic process by positive regulation of transcription from RNA polymerase II promoter|upregulation of cellular alcohol catabolic process by positive regulation of transcription from RNA polymerase II promoter|up-regulation of cellular alcohol catabolic process by positive regulation of transcription from RNA polymerase II promoter					This term was obsoleted because it represents a GO-CAM model.		krc	2012-04-24T05:13:25Z		True			biological_process											owl:Class	
GO:0005155	biolink:NamedThing	obsolete epidermal growth factor receptor activating ligand activity	OBSOLETE. This term was not defined before being made obsolete.	tmpzr1t_l9r_go_relaxed.owl	EGFR activating ligand activity|EGF receptor activating ligand activity|epidermal growth factor receptor activating ligand activity			GO:0005154		This term was made obsolete because it represents both a biological process and a molecular function.	GO:0030297|GO:0045741				True			molecular_function											owl:Class	
GO:0030064	biolink:NamedThing	obsolete cell wall inner membrane	OBSOLETE. The peptidoglycan layer of the cell wall of Gram-negative bacteria.	tmpzr1t_l9r_go_relaxed.owl	cell wall inner membrane					This term was made obsolete because it was defined inaccurately.	GO:0009276				True			cellular_component											owl:Class	
GO:1901644	biolink:NamedThing	obsolete positive regulation of tRNA methylation in response to nitrogen starvation	OBSOLETE. Any process that activates or increases the frequency, rate or extent of tRNA methylation in response to nitrogen starvation.	tmpzr1t_l9r_go_relaxed.owl	upregulation of tRNA methylation in response to nitrogen starvation|up regulation of tRNA methylation in response to nitrogen starvation|activation of tRNA methylation in response to nitrogen starvation|up-regulation of tRNA methylation in response to nitrogen starvation							al	2012-11-16T14:44:12Z		True			biological_process											owl:Class	
GO:0009463	biolink:NamedThing	obsolete cytochrome b/b6	OBSOLETE. Diheme cytochrome b; cytochrome b has the hemes b(562) and b(566) and is a component of the mitochondrial respiratory chain complex III. Cytochrome b6 is a component of bc complex acting between photosystems II and I of photosynthesis.	tmpzr1t_l9r_go_relaxed.owl	cytochrome b/b6			GO:0045158		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0071427	biolink:NamedThing	obsolete mRNA-containing ribonucleoprotein complex export from nucleus	OBSOLETE. The directed movement of a ribonucleoprotein complex that contains messenger RNA from the nucleus to the cytoplasm.	tmpzr1t_l9r_go_relaxed.owl	mRNA-containing ribonucleoprotein complex export from cell nucleus|mRNA-containing ribonucleoprotein complex nucleus export|mRNA-containing ribonucleoprotein complex transport from nucleus to cytoplasm|mRNA-containing RNP export from nucleus	https://github.com/geneontology/go-ontology/issues/22246				This term has been obsoleted because it represents the transport of a carrier bound to its substrate.	GO:0006406	mah	2009-12-16T10:13:59Z		True			biological_process											owl:Class	
GO:1990560	biolink:NamedThing	obsolete DNA methyltransferase binding	OBSOLETE. Binding to a DNA methyltransferase.	tmpzr1t_l9r_go_relaxed.owl	DNA methyltransferase binding					This term was obsoleted at the TermGenie Gatekeeper stage.		sl	2014-11-19T16:30:28Z		True			molecular_function											owl:Class	
GO:0016541	biolink:NamedThing	obsolete intein	OBSOLETE. Intervening protein sequence excised from a protein precursor in protein splicing; inteins catalyze their own excision and many also possess endonuclease activity.	tmpzr1t_l9r_go_relaxed.owl	intein					This term was made obsolete because it refers to a protein sequence feature.	GO:0016539|GO:0004519				True			molecular_function											owl:Class	
GO:0008149	biolink:NamedThing	obsolete para-aminobenzoic acid (PABA) synthase	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	para-aminobenzoic acid (PABA) synthase					This term was made obsolete because it refers to two different functions, a glutamine amidotransferase that functions as an aminodeoxychorismate synthase [itself composed of two enzymatic activities, a glutaminase and a chorismate aminase (this latter is sometimes referred to as the aminodeoxychorismate synthase)] and a 4-amino-4-deoxychorismate aromatase (4-amino-4-deoxychorismate lyase). Note that the name 'para-amino benzoate synthase' was initially given to the 'aminodeoxychorismate synthase' activity before the additional lyase activity was discovered.	GO:0046820|GO:0008696				True			molecular_function											owl:Class	
GO:0006130	biolink:NamedThing	obsolete 6-phosphofructokinase reduction	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	6-phosphofructokinase reduction					This term was made obsolete because the term string was ambiguous and the term may represent a molecular function.	GO:0003872|GO:0022900				True			biological_process											owl:Class	
GO:0015282	biolink:NamedThing	obsolete NADPH oxidase-associated cytochrome b558 hydrogen channel activity	OBSOLETE. This term was not defined before being made obsolete.	tmpzr1t_l9r_go_relaxed.owl	NADPH oxidase-associated cytochrome b558 proton channel|NADPH oxidase-associated cytochrome b558 hydrogen channel activity					This term was made obsolete because it describes a gene product rather than a function.					True			molecular_function											owl:Class	
GO:0042290	biolink:NamedThing	obsolete URM1 hydrolase activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	URM1 hydrolase activity					This term was made obsolete because it cannot be determined what its intended meaning was, because the term name is not found in the literature.	GO:0019783				True			molecular_function											owl:Class	
GO:0023049	biolink:NamedThing	obsolete signal initiation by protein/peptide mediator	OBSOLETE. The process in which a protein/peptide signal causes activation of a receptor.	tmpzr1t_l9r_go_relaxed.owl	signal initiation by protein/peptide mediator					This term was made obsolete because the meaning of the term is ambiguous.	GO:0048018|GO:0038023|GO:0007165		2010-02-16T09:30:50Z		True			biological_process											owl:Class	
GO:0030823	biolink:NamedThing	obsolete regulation of cGMP metabolic process	OBSOLETE. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving cGMP.	tmpzr1t_l9r_go_relaxed.owl	regulation of cGMP metabolism					The reason for obsoletion is that this term represents the regulation of a signaling pathway, not regulation of metabolism.					True			biological_process											owl:Class	
GO:0046803	biolink:NamedThing	obsolete reduction of virulence	OBSOLETE. Any process that stops, prevents or reduces the severity of viral infection and subsequent disease.	tmpzr1t_l9r_go_relaxed.owl	reduction of virulence					This term was made obsolete because 'virulence' is not a biological process; however, alteration of virulence also does not fit under 'regulation of biological quality ; GO:0065008' because it is a product both of the genotype/phenotype of the infecting organism and the genotype/phenotype of the organism being infected and varies by individual within a species both for the infecting organism and the infected organism.					True			biological_process											owl:Class	
GO:1904112	biolink:NamedThing	obsolete positive regulation of plus-end directed microfilament motor activity	OBSOLETE. Any process that activates or increases the frequency, rate or extent of plus-end directed microfilament motor activity.	tmpzr1t_l9r_go_relaxed.owl	upregulation of plus-end directed microfilament motor activity|up-regulation of plus-end directed microfilament motor activity|up regulation of plus-end directed actin filament motor activity|up-regulation of plus-end directed actin filament motor activity|activation of plus-end directed actin filament motor activity|upregulation of barbed-end directed actin-filament motor activity|positive regulation of barbed-end directed actin-filament motor activity|up-regulation of plus-end directed actin-filament motor activity|up regulation of barbed-end directed actin-filament motor activity|up regulation of plus-end directed actin-filament motor activity|activation of barbed-end directed actin-filament motor activity|positive regulation of plus-end directed actin-filament motor activity|activation of plus-end directed actin-filament motor activity|upregulation of plus-end directed actin-filament motor activity|up-regulation of barbed-end directed actin-filament motor activity|activation of plus-end directed microfilament motor activity|positive regulation of plus-end directed actin filament motor activity|up regulation of plus-end directed microfilament motor activity|upregulation of plus-end directed actin filament motor activity	https://github.com/geneontology/go-ontology/issues/21626				This term was obsoleted because it represents a molecular function.	GO:0140659	kmv	2015-04-03T18:28:35Z		True			biological_process											owl:Class	
GO:0061393	biolink:NamedThing	obsolete positive regulation of transcription from RNA polymerase II promoter in response to osmotic stress	OBSOLETE. Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/12739				This term was obsoleted because it represents a GO-CAM model.	GO:0045944|GO:0071470	dph	2011-12-13T08:58:20Z		True			biological_process											owl:Class	
GO:1904721	biolink:NamedThing	obsolete negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response	OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of mRNA endonucleolytic cleavage involved in unfolded protein response.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of XBP1 mRNA cleavage|down-regulation of HAC1-type intron splice site recognition and cleavage|downregulation of IRE1-mediated XBP-1 mRNA cleavage|inhibition of HAC1-type intron splice site recognition and cleavage|downregulation of mRNA endonucleolytic cleavage involved in unfolded protein response|inhibition of IRE1-mediated XBP-1 mRNA cleavage|down regulation of mRNA endonucleolytic cleavage involved in unfolded protein response|down regulation of XBP1 mRNA cleavage|downregulation of HAC1-type intron splice site recognition and cleavage|negative regulation of IRE1-mediated XBP-1 mRNA cleavage|inhibition of HAC1 mRNA cleavage|down-regulation of HAC1 mRNA cleavage|down-regulation of IRE1-mediated XBP-1 mRNA cleavage|negative regulation of XBP1 mRNA cleavage|down regulation of HAC1 mRNA cleavage|down regulation of HAC1-type intron splice site recognition and cleavage|negative regulation of HAC1 mRNA cleavage|downregulation of XBP1 mRNA cleavage|inhibition of XBP1 mRNA cleavage|down-regulation of mRNA endonucleolytic cleavage involved in unfolded protein response|inhibition of mRNA endonucleolytic cleavage involved in unfolded protein response|down regulation of IRE1-mediated XBP-1 mRNA cleavage|negative regulation of HAC1-type intron splice site recognition and cleavage|downregulation of HAC1 mRNA cleavage					The reason for obsoletion is that this process being regulated (GO:0070055 mRNA endonucleolytic cleavage involved in unfolded protein response) was obsoleted.	GO:1903895	bf	2015-10-08T14:52:55Z		True			biological_process											owl:Class	
GO:0000191	biolink:NamedThing	obsolete activation of MAPKKK (pseudohyphal growth)	OBSOLETE. Upregulation of MAPKKK activity in the context of regulating pseudohyphal or invasive growth.	tmpzr1t_l9r_go_relaxed.owl	activation of MAPKKK (pseudohyphal growth)					This term was made obsolete because it is a gene product specific term.					True			biological_process											owl:Class	
GO:0015429	biolink:NamedThing	obsolete peroxisomal fatty acyl transporter	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	peroxisomal fatty acyl transporter					This term was made obsolete because it describes a gene product and it contains both component and function information.					True			molecular_function											owl:Class	
GO:0100024	biolink:NamedThing	obsolete regulation of carbohydrate metabolic process by transcription from RNA polymerase II promoter	OBSOLETE. Any transcription from RNA polymerase II promoter process that regulates carbohydrate metabolic process.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it represents a GO-CAM model.		cjm	2015-04-02T04:13:19Z		True			biological_process											owl:Class	
GO:0052409	biolink:NamedThing	obsolete metabolism by organism of cell wall cellulose in other organism involved in symbiotic interaction	OBSOLETE. The chemical reactions and pathways performed by an organism involving cellulose in the cell wall of a second organism, where the two organisms are in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	metabolism by organism of cell wall cellulose in other organism during symbiotic interaction	https://github.com/geneontology/go-ontology/issues/21396				This term was obsoleted because it represents an unnecessary grouping class.					True			biological_process											owl:Class	
GO:0046758	biolink:NamedThing	obsolete lytic virus budding from Golgi membrane	OBSOLETE. A form of viral release in which the nucleocapsid evaginates from the host Golgi membrane system, resulting in envelopment of the virus and cell lysis.	tmpzr1t_l9r_go_relaxed.owl	lytic viral budding from Golgi membrane|lytic Golgi membrane viral budding|lytic virus budding from Golgi membrane					This term was made obsolete because it does not appear to correspond to a real biological process.					True			biological_process											owl:Class	
GO:0039598	biolink:NamedThing	obsolete induction by virus of host nuclear polyadenylation-dependent mRNA catabolic process	OBSOLETE. The process in which a virus increases the frequency, rate or extent of the breakdown of host messenger RNA (mRNA) initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target mRNA.	tmpzr1t_l9r_go_relaxed.owl	induction by virus of host nuclear polyadenylation-dependent mRNA catabolic process|virus-mediated host mRNA decay by hyperadenylation|induction by virus of host nuclear poly(A)-dependent mRNA catabolic process					This term was made obsolete because it is unclear what role the viral protein is playing in this process. and there is insufficient evidence to use this term for annotation.		bf	2012-07-04T04:44:16Z		True			biological_process											owl:Class	
GO:0001311	biolink:NamedThing	obsolete formation of extrachromosomal circular rDNA by homologous recombination involved in replicative cell aging	OBSOLETE. Excision from the chromosome and circularization of DNA molecules encoding ribosomal RNA in dividing cells as they age.	tmpzr1t_l9r_go_relaxed.owl	formation of extrachromosomal circular rDNA by homologous recombination during replicative cell ageing|formation of extrachromosomal circular ribosomal DNA by homologous recombination during replicative cell aging|assembly of extrachromosomal circular rDNA by homologous recombination involved in replicative cell aging|formation of extrachromosomal circular rDNA by homologous recombination during replicative cell aging	https://github.com/geneontology/go-ontology/issues/20007				This term was obsoleted because it represents an assay, not a true biological process.					True			biological_process											owl:Class	
GO:0008539	biolink:NamedThing	obsolete proteasome inhibitor activity	OBSOLETE. Stops, prevents or reduces the activity of the proteasome complex. The proteasome complex performs regulated ubiquitin-dependent cytosolic and nuclear proteolysis.	tmpzr1t_l9r_go_relaxed.owl	proteasome inhibitor activity|PI-31					The term was made obsolete because 'proteasome' is not a valid molecular function term.	GO:0061136|GO:0004866				True			molecular_function											owl:Class	
GO:0072481	biolink:NamedThing	obsolete detection of stimulus involved in mitotic spindle orientation checkpoint	OBSOLETE. The series of events in which information about whether the spindle is correctly oriented is received and converted into a molecular signal, contributing to a mitotic cell cycle spindle orientation checkpoint.	tmpzr1t_l9r_go_relaxed.owl	mitotic cell cycle spindle orientation checkpoint sensor process|detection of stimulus involved in mitotic cell cycle spindle orientation checkpoint|sensing involved in mitotic cell cycle spindle orientation checkpoint|mitotic cell cycle spindle orientation checkpoint sensor mechanism	https://github.com/geneontology/go-ontology/issues/20976				This term was obsoleted because it corresponds to a molecular function.		mah	2010-12-09T12:11:52Z		True			biological_process											owl:Class	
GO:0052439	biolink:NamedThing	obsolete modulation by organism of defense-related symbiont cell wall callose deposition	OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of the deposition of callose by the symbiont in its cell walls, occurring as part of the defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	modulation by organism of defense-related symbiont cell wall callose deposition					This term was made obsolete because it does not represent a real biological process.					True			biological_process											owl:Class	
GO:0009468	biolink:NamedThing	obsolete diheme class I cytochrome c	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	diheme class I cytochrome c					This term was made obsolete because it represents a gene product.	GO:0009055				True			molecular_function											owl:Class	
GO:0006088	biolink:NamedThing	obsolete acetate to acetyl-CoA	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	acetate to acetyl-CoA					This term was made obsolete because it represents a function rather than a process.	GO:0003987				True			biological_process											owl:Class	
GO:0022815	biolink:NamedThing	obsolete large uncharged polar molecule transmembrane transporter activity	OBSOLETE. Catalysis of the transfer of a large uncharged polar molecule from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	large uncharged polar molecule transmembrane transporter activity			GO:0022857		This term was made obsolete because 'large uncharged polar molecule' is not a useful chemical grouping term.					True			molecular_function											owl:Class	
GO:0004717	biolink:NamedThing	obsolete focal adhesion kinase activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	focal adhesion kinase activity|FAK			GO:0004713		This term was made obsolete because it represents a gene product, and because the gene was named after its location of action rather than after its molecular function.					True			molecular_function											owl:Class	
GO:0051411	biolink:NamedThing	obsolete ALP binding	OBSOLETE. Interacting selectively and non-covalently wih ALP, actinin-associated LIM protein of the Z band. ALP is a PDZ/LIM domain protein found in the Z band.	tmpzr1t_l9r_go_relaxed.owl	ALP binding|actinin-associated LIM protein binding			GO:0008092		This term was made obsolete because it represents binding to an individual protein.					True			molecular_function											owl:Class	
GO:0052525	biolink:NamedThing	obsolete positive regulation by host of symbiont signal transduction pathway	OBSOLETE. Any process in which an organism activates, maintains or increases the frequency, rate or extent of the symbiont signal transduction pathways, the cascade of processes by which a signal interacts with a receptor. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	up-regulation by host of symbiont signal transduction pathway|activation by host of symbiont signal transduction pathway|stimulation by host of symbiont signal transduction pathway|upregulation by host of symbiont signal transduction pathway|up regulation by host of symbiont signal transduction pathway					The reason for obsoletion is that there is no evidence that the host can modulate or regulate a symbiont's signal transduction pathway.					True			biological_process											owl:Class	
GO:0052412	biolink:NamedThing	obsolete metabolism by host of symbiont cell wall pectin	OBSOLETE. The chemical reactions and pathways performed by an organism involving pectin in the cell wall of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/21396				This term was obsoleted because there is no evidence it exists.					True			biological_process											owl:Class	
GO:0001322	biolink:NamedThing	obsolete age-dependent response to oxidative stress involved in replicative cell aging	OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) occurring in dividing cells as they age as a result of oxidative stress, where the change varies according to the age of the cell or organism.	tmpzr1t_l9r_go_relaxed.owl	age-dependent response to oxidative stress during replicative cell aging|age-dependent response to oxidative stress during replicative cell ageing	https://github.com/geneontology/go-ontology/issues/20007				This term was obsoleted because it represents an assay, not a true biological process.					True			biological_process											owl:Class	
RO:0002412	biolink:NamedThing	immediately causally upstream of		tmpzr1t_l9r_go_relaxed.owl					RO:0002412									external									immediately_causally_upstream_of			
GO:0044136	biolink:NamedThing	obsolete development of symbiont on or near host rhizosphere	OBSOLETE. The progression of the symbiont from an initial condition to a later condition, occurring on or near its host rhizosphere. The host rhizosphere is defined as total below-ground surfaces of a plant as a habitat for its symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl						The reason for obsoletion is that this term represents both a process and a component		jl	2009-08-04T04:18:35Z		True			biological_process											owl:Class	
GO:1900527	biolink:NamedThing	obsolete regulation of nucleus size involved in G1 to G0 transition	OBSOLETE. Any regulation of nucleus size that is involved in G1 to G0 transition.	tmpzr1t_l9r_go_relaxed.owl	regulation of nucleus size involved in cell cycle quiescence|regulation of nuclear volume involved in G1/G0 transition|regulation of nuclear volume involved in cell cycle quiescence|regulation of nucleus size involved in G1 to G0 transition|regulation of nuclear size involved in G1/G0 transition|regulation of nuclear volume involved in establishment of cell quiescence|regulation of nucleus size involved in establishment of cell quiescence|regulation of nuclear size involved in cell cycle quiescence|regulation of nuclear volume involved in G1 to G0 transition|regulation of nuclear size involved in G1 to G0 transition|regulation of nucleus size involved in stationary phase|regulation of nucleus size involved in G1/G0 transition|regulation of nuclear volume involved in stationary phase|regulation of nuclear size involved in stationary phase|regulation of nuclear size involved in establishment of cell quiescence					This term was made obsolete because it represents a phenotype.		al	2012-05-08T10:39:01Z		True			biological_process											owl:Class	
GO:1990721	biolink:NamedThing	obsolete prostatic acid phosphatase complex	OBSOLETE. A protein complex that is capable of dephosphorylation of alky, aryl and acyl orthophosphate monoesters and phosphorylated proteins. Optimal activity in acidic environment (pH 4-6). In mammals it consists of a homodimer of ACPP.	tmpzr1t_l9r_go_relaxed.owl	prostatic acid phosphatase complex|ACPP homodimer complex|PAP complex					This term was obsoleted at the TermGenie Gatekeeper stage.		bhm	2015-04-01T09:43:14Z		True			cellular_component											owl:Class	
OIO:hasOBONamespace	biolink:NamedThing	has_obo_namespace		tmpzr1t_l9r_go_relaxed.owl																									owl:AnnotationProperty	
GO:0038077	biolink:NamedThing	obsolete MAP kinase kinase kinase activity involved in innate immune response	OBSOLETE. Catalysis of the phosphorylation and activation of a MAP kinase kinase (MAPKK), as part of a MAPK signaling cascade that contributes to an innate immune response.	tmpzr1t_l9r_go_relaxed.owl	MAP3K activity involved in innate immune response|MAPKKK activity involved in innate immune response					This term has been obsoleted because it represents a GO-CAM model rather than a single GO term.		bf	2012-01-26T02:35:52Z		True			molecular_function											owl:Class	
GO:0000259	biolink:NamedThing	obsolete intracellular nucleoside transmembrane transporter activity	OBSOLETE. Enables the directed movement of a nucleoside, a nucleobase linked to either beta-D-ribofuranose (ribonucleoside) or 2-deoxy-beta-D-ribofuranose (a deoxyribonucleotide) within a cell.	tmpzr1t_l9r_go_relaxed.owl	intracellular nucleoside transmembrane transporter activity					This term was made obsolete because it contains component and function information.	GO:0005622|GO:0005337				True			molecular_function											owl:Class	
GO:0007241	biolink:NamedThing	obsolete inactivation of Hog1	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	inactivation of Hog1					This term was made obsolete because it contains gene product and species specific information.					True			biological_process											owl:Class	
GO:0075073	biolink:NamedThing	obsolete autophagy of symbiont cells on or near host surface	OBSOLETE. The process in which symbiont cells digest parts of their own cytoplasm, occurring when the symbiont is on or near its host surface. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl						The reason for obsoletion is that this term did not represent any specific host/symbiont process.					True			biological_process											owl:Class	
GO:0006329	biolink:NamedThing	obsolete satellite DNA binding	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	satellite DNA binding			GO:0003696		This term was made obsolete because it represents a molecular function and not a biological process.					True			biological_process											owl:Class	
GO:0008563	biolink:NamedThing	obsolete alpha-factor sex pheromone exporter	OBSOLETE. Catalysis of the reaction: ATP + H2O + alpha-factor(in) = ADP + phosphate + alpha-factor(out). The export of the alpha-factor sex pheromone by an ABC-type (ATP-binding cassette-type) ATPase, characterized by the presence of two similar ATP-binding domains, that does not undergo phosphorylation during the transport process.	tmpzr1t_l9r_go_relaxed.owl	alpha-factor-transporting ATPase|alpha-factor sex pheromone exporter					This term was made obsolete because this function does not exist; alpha-factor is secreted by the classical secretion pathway and not exported.					True			molecular_function											owl:Class	
GO:0016729	biolink:NamedThing	obsolete oxidoreductase activity, acting on CH2 groups, other acceptors	OBSOLETE. Catalysis of an oxidation-reduction (redox) reaction in which a CH2 group acts as a hydrogen or electron donor and reduces an acceptor other than disulfide, NAD, NADP or oxygen.	tmpzr1t_l9r_go_relaxed.owl	oxidoreductase activity, acting on CH2 groups, other acceptors					This term was made obsolete because it was an unnecessary grouping term.	GO:0016725				True			molecular_function											owl:Class	
GO:0008025	biolink:NamedThing	obsolete diazepam binding inhibitor activity	OBSOLETE. The diazepam binding inhibitor is a 10kDa 86-residue polypeptide that acts as an endogenous ligand for a mitochondrial receptor (formerly regarded as a peripheral benzodiazepine binding site) in steroidogenic cells and regulates stimulation of steroidogenesis by tropic hormones. It also binds to the GABA-A receptor and modulates glucose-dependent insulin secretion and synthesis of acyl-CoA esters.	tmpzr1t_l9r_go_relaxed.owl	diazepam binding inhibitor activity|diazepam-binding inhibitor activity|DBI					This term was made obsolete because it represents a multifunctional gene product.	GO:0050809|GO:0050796|GO:0050810|GO:0050812|GO:0004857|GO:0030156|GO:0050811				True			molecular_function											owl:Class	
GO:0009471	biolink:NamedThing	obsolete class III cytochrome c	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	class III cytochrome c					This term was made obsolete because it represents a gene product.	GO:0009055				True			molecular_function											owl:Class	
GO:0052521	biolink:NamedThing	obsolete positive regulation by host of symbiont phagocytosis	OBSOLETE. Any process in which an organism activates, maintains or increases the frequency, rate or extent of phagocytosis, the engulfing by phagocytes of external particulate material, in the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	upregulation by host of symbiont phagocytosis|up-regulation by host of symbiont phagocytosis|up regulation by host of symbiont phagocytosis|stimulation by host of symbiont phagocytosis|activation by host of symbiont phagocytosis	https://github.com/geneontology/go-ontology/issues/18562				This term was obsoleted because there is no evidence that this process exists.					True			biological_process											owl:Class	
GO:0004231	biolink:NamedThing	obsolete insulysin activity	OBSOLETE. Catalysis of the degradation of insulin, glucagon and other polypeptides. No action on proteins.	tmpzr1t_l9r_go_relaxed.owl	insulin-degrading neutral proteinase activity|insulinase activity|insulin proteinase activity|insulysin activity|insulin protease activity|insulin-glucagon protease activity|IDE|insulin-specific protease activity|metalloinsulinase activity|insulin-degrading enzyme activity			GO:0004222		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0005565	biolink:NamedThing	obsolete mitochondrial tRNA	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	mitochondrial tRNA					Note that this term was deleted from GO rather than being made obsolete and was restored to the ontology in Feb 2003 to ensure that the ID is not reused.					True			cellular_component											owl:Class	
GO:0046240	biolink:NamedThing	obsolete xylene biosynthetic process	OBSOLETE. The chemical reactions and pathways resulting in the formation of xylene, a mixture of three colorless, aromatic hydrocarbon liquids, ortho-, meta- and para-xylene.	tmpzr1t_l9r_go_relaxed.owl	xylene biosynthesis|xylene synthesis|xylene anabolism|xylene formation|xylene biosynthetic process			GO:0018948		This term was made obsolete because xylene is not synthesized by living organisms, and GO does not cover non-biological processes.					True			biological_process											owl:Class	
GO:1900536	biolink:NamedThing	obsolete regulation of glucose homeostasis	OBSOLETE. Any process that modulates the frequency, rate or extent of glucose homeostasis.	tmpzr1t_l9r_go_relaxed.owl	regulation of glucose homeostasis					This term was obsoleted at the TermGenie Gatekeeper stage.		hjd	2012-05-10T06:52:21Z		True			biological_process											owl:Class	
GO:0090418	biolink:NamedThing	obsolete positive regulation of transcription involved in S-phase of mitotic cell cycle	OBSOLETE. Any process that activates or increases the frequency, rate or extent of transcription of target genes that are transcribed as part of the S phase of the mitotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl	activation of transcription involved in S phase of mitotic cell cycle|up-regulation of transcription from RNA polymerase II promoter during S phase of the mitotic cell cycle|activation of transcription from RNA polymerase II promoter during S phase of the mitotic cell cycle|activation of S phase specific transcription in the mitotic cell cycle|up-regulation of transcription involved in S phase of mitotic cell cycle|positive regulation of transcription from RNA polymerase II promoter during S phase of the mitotic cell cycle|positive regulation of transcription involved in S-phase of mitotic cell cycle|positive regulation of S phase specific transcription in the mitotic cell cycle|up-regulation of S phase specific transcription in the mitotic cell cycle					This term was made obsolete because it is unclear exactly what it means. It could mean either 'regulation of transcription during phase X' or 'regulation of transition between phase X and phase Y'.	GO:0000083|GO:0045944	tb	2011-10-26T03:54:00Z		True			biological_process											owl:Class	
GO:0042563	biolink:NamedThing	obsolete importin alpha-subunit nuclear export complex	OBSOLETE. A protein complex which usually consists of three components, e.g. in Xenopus, the importin alpha-subunit/CAS/Ran, and which functions to transport the importin alpha-subunit out of the nucleus through the nuclear pore.	tmpzr1t_l9r_go_relaxed.owl						The reason for obsoletion is that these terms include the substrate of the reaction.					True			cellular_component											owl:Class	
GO:1902592	biolink:NamedThing	obsolete multi-organism membrane budding	OBSOLETE. A membrane budding which involves another organism.	tmpzr1t_l9r_go_relaxed.owl	multi organism membrane budding					Obsoleted because it was a grouping term for a viral process that was incorrectly under 'multi-organism cellular process'. The children terms have been moved under 'viral process', so that this grouping term is not necessary anymore.		jl	2013-12-19T15:26:25Z		True			biological_process											owl:Class	
GO:0018512	biolink:NamedThing	obsolete 1,6-dihydroxy-5-methylcyclohexa-2,4-dienecarboxylate dehydrogenase activity	OBSOLETE. Catalysis of the reaction: 1,6-dihydroxy-5-methylcyclohexa-2,4-dienecarboxylate + NAD+ = 3-methylcatechol + CO2 + NADH + H+.	tmpzr1t_l9r_go_relaxed.owl	1,6-dihydroxy-5-methylcyclohexa-2,4-dienecarboxylate dehydrogenase activity|1,2-dihydroxy-3-methylcyclohexa-3,5-diene-carboxylate dehydrogenase activity				UM-BBD_reactionID:r0216	This term was made obsolete because, according to the Enzyme Commission, there is no evidence that this enzymatic activity exists.					True			molecular_function											owl:Class	
GO:0008580	biolink:NamedThing	obsolete cytoskeletal regulator activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	cytoskeletal regulator activity					This term was made obsolete because 'cytoskeleton' is not an activity, and regulation of its distribution or modification belongs in the process ontology.	GO:0007010				True			molecular_function											owl:Class	
GO:0052528	biolink:NamedThing	obsolete upregulation by organism of symbiont programmed cell death	OBSOLETE. Any process by which an organism increases the frequency, rate or extent of programmed cell death in the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	enhancement of symbiont programmed cell death by organism|upregulation by organism of symbiont programmed cell death					This term was made obsolete because it does not represent a real biological process.					True			biological_process											owl:Class	
GO:0019157	biolink:NamedThing	obsolete malate oxidase activity	OBSOLETE. Catalysis of the reaction: (S)-malate + O(2) = H(2)O(2) + oxaloacetate.	tmpzr1t_l9r_go_relaxed.owl	(S)-malate:oxygen oxidoreductase activity|malic dehydrogenase II|malic oxidase activity|FAD-dependent malate oxidase activity					This term is slated for obsoletion because RHEA indicates there is not enough experimental evidence.					True			molecular_function											owl:Class	
GO:0001313	biolink:NamedThing	obsolete formation of extrachromosomal circular DNA involved in replicative cell aging	OBSOLETE. Excision from the chromosome and circularization of a region of chromosomal DNA, generally, but not always, via homologous recombination between direct tandem repeats, in dividing cells as they age.	tmpzr1t_l9r_go_relaxed.owl	formation of extrachromosomal circular DNA during replicative cell aging|assembly of extrachromosomal circular DNA involved in replicative cell aging|formation of extrachromosomal circular DNA during replicative cell ageing	https://github.com/geneontology/go-ontology/issues/20007				This term was obsoleted because it represents an assay, not a true biological process.					True			biological_process											owl:Class	
GO:1990642	biolink:NamedThing	obsolete response to castration	OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a castration stimulus, deprivation of gonads.	tmpzr1t_l9r_go_relaxed.owl	response to castration					This term was obsoleted at the TermGenie Gatekeeper stage.		sl	2015-02-11T18:53:04Z		True			biological_process											owl:Class	
GO:0009458	biolink:NamedThing	obsolete cytochrome	OBSOLETE. A hemeprotein whose characteristic mode of action involves transfer of reducing equivalents associated with a reversible change in oxidation state of the prosthetic group. This redox change involves a single electron, reversible equilibrium between the Fe(II) and Fe(III) states of the central iron atom.	tmpzr1t_l9r_go_relaxed.owl	cytochrome					This term was made obsolete because it represents a gene product.	GO:0004129				True			molecular_function											owl:Class	
GO:0009108	biolink:NamedThing	obsolete coenzyme biosynthetic process	OBSOLETE. The chemical reactions and pathways resulting in the formation of coenzymes, any of various nonprotein organic cofactors that are required, in addition to an enzyme and a substrate, for an enzymatic reaction to proceed.	tmpzr1t_l9r_go_relaxed.owl	coenzyme synthesis|coenzyme anabolism|coenzyme biosynthesis|coenzyme formation|coenzyme and prosthetic group biosynthetic process|coenzyme and prosthetic group biosynthesis					1. Making inferences in GO about compounds based on the coenzyme role curated by ChEBI creates relationships that are not always true which violates ontological principles for GO; therefore we will cease making these inferences. 2. It is not meaningful to group biosynthetic processes that are not all metabolically related by the fact that they may be used as a coenzyme.					True			biological_process											owl:Class	
GO:0051814	biolink:NamedThing	obsolete movement in other organism involved in symbiotic interaction	OBSOLETE. The process in which an organism or its progeny spreads from one location to another within a second organism, where the two organisms are in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	movement within other organism during symbiotic interaction|movement in other organism during symbiotic interaction					This term was obsoleted because it represented both a process and a location.					True			biological_process											owl:Class	
GO:0006299	biolink:NamedThing	obsolete short patch mismatch repair system	OBSOLETE. The repair of mismatched DNA where the gap to be repaired is only one nucleotide. DNA polymerase is the preferred polymerase in short patch repair, performing gap filling DNA synthesis and removal of the 5'-deoxyribose phosphate of the abasic site.	tmpzr1t_l9r_go_relaxed.owl	short patch mismatch repair system					This term was made obsolete because 'short patch' is a relative statement, often used ambiguously, and does not necessarily represent a process; the processes it can stand for are base excision repair, nucleotide excision repair, transcription-coupled nucleotide excision repair, and mismatch repair.	GO:0006289|GO:0006284				True			biological_process											owl:Class	
GO:0003750	biolink:NamedThing	obsolete cell cycle regulator	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	cell cycle regulator			GO:0051726		This term was made obsolete because it does not represent a single molecular function.					True			molecular_function											owl:Class	
GO:0015427	biolink:NamedThing	obsolete ABC-type efflux porter activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	ABC-type efflux porter activity					This term was made obsolete because ABC transporters are a protein family rather than a functional grouping.	GO:0043190|GO:0042626				True			molecular_function											owl:Class	
GO:0035391	biolink:NamedThing	obsolete maintenance of chromatin silencing at silent mating-type cassette	OBSOLETE. The maintenance of chromatin in a transcriptionally silent state such as heterochromatin at silent mating-type loci.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/19301				This term was obsoleted because it represents a phenotype.		bf	2010-03-22T10:25:14Z		True			biological_process											owl:Class	
GO:0005735	biolink:NamedThing	obsolete box H + ACA snoRNP protein	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	box H + ACA snoRNP protein					This term was made obsolete because it represents a gene product.					True			cellular_component											owl:Class	
GO:1990495	biolink:NamedThing	obsolete actin filament organization involved in mitotic cytokinetic actomyosin contractile ring assembly	OBSOLETE. An actin filament organization process that contributes to actomyosin contractile ring assembly during mitotic cytokinesis.	tmpzr1t_l9r_go_relaxed.owl	actin filament organization involved in mitotic cytokinetic actomyosin contractile ring assembly					This term was obsoleted at the TermGenie Gatekeeper stage.		al	2014-09-25T09:19:27Z		True			biological_process											owl:Class	
GO:2000775	biolink:NamedThing	obsolete histone H3-S10 phosphorylation involved in chromosome condensation	OBSOLETE. Any histone H3-S10 phosphorylation that is involved in chromosome condensation.	tmpzr1t_l9r_go_relaxed.owl	histone H3 phosphorylation at S10 of chromosome condensation|histone H3-S10 phosphorylation of chromosome condensation	https://github.com/geneontology/go-ontology/issues/22321				This term was obsoleted because it is a molecular function represented as a biological process.		mah	2011-06-22T03:58:00Z		True			biological_process											owl:Class	
GO:0030074	biolink:NamedThing	obsolete thylakoid (sensu Proteobacteria)	OBSOLETE. A thylakoid; as in, but not restricted to, the purple bacteria and relatives (Proteobacteria, ncbi_taxonomy_id:1224).	tmpzr1t_l9r_go_relaxed.owl	thylakoid (sensu Proteobacteria)					This term was made obsolete because thylakoids are not found in organisms of the Phylum Proteobacteria.	GO:0042716				True			cellular_component											owl:Class	
GO:0006894	biolink:NamedThing	obsolete Golgi to secretory vesicle transport	OBSOLETE. The directed movement of proteins from the Golgi to one of two types of secretory vesicle. Continuously secreted proteins are sorted into transport vesicles that fuse with the plasma membrane, releasing their contents by exocytosis. Specialized secretory cells have a second secretory pathway in which soluble proteins and other substances are initially stored in secretory vesicles for later release.	tmpzr1t_l9r_go_relaxed.owl	Golgi to secretory vesicle transport, vesicle-mediated|Golgi to secretory vesicle transport					This term was made obsolete because it mixes two processes that can be better captured in separate terms.	GO:0055108|GO:0055107				True			biological_process											owl:Class	
GO:0039589	biolink:NamedThing	obsolete suppression by virus of host TAP complex	OBSOLETE. Any process in which a virus stops, prevents, or reduces the activity of the host TAP complex, a heterodimer composed of the subunits TAP1 and TAP2 (transporter associated with antigen presentation). The TAP complex functions in the transport of antigenic peptides from the cytosol to the lumen of the endoplasmic reticulum, where they are loaded onto the MHC class I. By inhibiting the TAP complex, the virus prevents viral particles being presented at the cell surface, and thus evades the host immune response.	tmpzr1t_l9r_go_relaxed.owl	inhibition of host TAP by virus				VZ:817	This term was obsoleted because this type of process is now represented by the actual function inhibited.	GO:0039588	bf	2012-06-22T14:42:06Z		True			biological_process											owl:Class	
GO:0042739	biolink:NamedThing	obsolete endogenous drug catabolic process	OBSOLETE. The chemical reactions and pathways resulting in the breakdown of a drug that has originated internally within the cell or organism.	tmpzr1t_l9r_go_relaxed.owl	endogenous drug degradation|endogenous drug breakdown|endogenous drug catabolism	https://github.com/geneontology/go-ontology/issues/21819				The reason for obsoletion is that there is no evidence that this process exists as a drug is by definition exogenous.					True			biological_process											owl:Class	
GO:0071426	biolink:NamedThing	obsolete ribonucleoprotein complex export from nucleus	OBSOLETE. The directed movement of a ribonucleoprotein complex from the nucleus to the cytoplasm.	tmpzr1t_l9r_go_relaxed.owl	ribonucleoprotein complex export from cell nucleus|ribonucleoprotein complex nucleus export|ribonucleoprotein complex transport from nucleus to cytoplasm|RNP export from nucleus	https://github.com/geneontology/go-ontology/issues/22246				This term has been obsoleted because it represents the transport of a carrier bound to its substrate.		mah	2009-12-16T10:13:01Z		True			biological_process											owl:Class	
GO:0008342	biolink:NamedThing	obsolete larval feeding behavior (sensu Insecta)	OBSOLETE. Feeding behavior in an insect larva.	tmpzr1t_l9r_go_relaxed.owl	larval feeding behavior (sensu Insecta)			GO:0030536		This term was made obsolete because there is no clear difference between the sensu Drosophila term and the generic term.					True			biological_process											owl:Class	
GO:0016550	biolink:NamedThing	obsolete insertion or deletion editing	OBSOLETE. The insertion into or deletion from an RNA molecule of nucleotide residues not encoded in DNA; takes place during or after transcription.	tmpzr1t_l9r_go_relaxed.owl	insertion/deletion editing|insertion or deletion editing					This term was made obsolete because it represents two separate processes (insertion and deletion).	GO:0070705|GO:0070706				True			biological_process											owl:Class	
GO:1905105	biolink:NamedThing	obsolete cellular response to ouabain	OBSOLETE. Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ouabain stimulus.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted at the TermGenie Gatekeeper stage.		sl	2016-04-04T19:08:16Z		True			biological_process											owl:Class	
GO:0075051	biolink:NamedThing	obsolete negative regulation of symbiont cell wall strengthening involved in entry into host	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of symbiont cell wall strengthening during entry into host. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of symbiont cell wall strengthening during entry into host					The reason for the obsoletion is that there is no evidence that those processes exist.					True			biological_process											owl:Class	
GO:0007578	biolink:NamedThing	obsolete aging dependent sterility (sensu Saccharomyces)	OBSOLETE. A haploid's inability to mate due to the loss of silencing at the mating-type loci, resulting in expression of both of the normally silent mating-type cassettes.	tmpzr1t_l9r_go_relaxed.owl	aging dependent sterility (sensu Saccharomyces)					This term was made obsolete because it reflected a trait or phenotype.	GO:0030466				True			biological_process											owl:Class	
GO:1905882	biolink:NamedThing	obsolete other organism cell wall	OBSOLETE. Any cell wall that is part of a other organism.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted at the TermGenie Gatekeeper stage.		pga	2017-01-31T10:57:28Z		True			cellular_component											owl:Class	
GO:0051437	biolink:NamedThing	obsolete positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition	OBSOLETE. Any process that activates, maintains or increases the rate of ubiquitin ligase activity that contributes to the regulation of the mitotic cell cycle phase transition.	tmpzr1t_l9r_go_relaxed.owl	activation of ubiquitin ligase activity during mitotic cell cycle|up-regulation of ubiquitin ligase activity during mitotic cell cycle|upregulation of ubiquitin ligase activity during mitotic cell cycle|stimulation of ubiquitin ligase activity during mitotic cell cycle|positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle|mitotic ubiquitin ligase activator|mitotic SCF complex activator|positive regulation of ubiquitin ligase activity during mitotic cell cycle|up regulation of ubiquitin ligase activity during mitotic cell cycle	https://github.com/geneontology/go-ontology/issues/15196				This term was obsoleted because it should be captured as a GO-CAM model.					True			biological_process											owl:Class	
GO:0005555	biolink:NamedThing	obsolete blood group antigen	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	blood group antigen					This term was made obsolete because it represents a gene product, and because describing something as an 'antigen' means that an organism can produce antibodies to it, which says nothing about the gene product activity.					True			molecular_function											owl:Class	
GO:0075212	biolink:NamedThing	obsolete positive regulation of transmembrane receptor-mediated cAMP signal transduction in response to host	OBSOLETE. Any process in which the symbiont organism activates, maintains or increases the frequency, rate or extent of its transmembrane receptor-mediated cAMP signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of symbiont transmembrane receptor-mediated cAMP signal transduction in response to host					This term was obsoleted because there is no evidence that this process exists.					True			biological_process											owl:Class	
GO:0005755	biolink:NamedThing	obsolete hydrogen-transporting ATP synthase, coupling factor CF(0)	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	hydrogen-transporting ATP synthase, coupling factor CF(0)					This term was made obsolete because more specific terms were created.	GO:0045263				True			cellular_component											owl:Class	
GO:0023038	biolink:NamedThing	obsolete signal initiation by diffusible mediator	OBSOLETE. The process in which a diffusible signal causes activation of a receptor.	tmpzr1t_l9r_go_relaxed.owl	signal initiation by diffusible mediator					This term was made obsolete because the meaning of the term is ambiguous.	GO:0007165|GO:0048018|GO:0038023|GO:0038001		2010-02-16T09:30:50Z		True			biological_process											owl:Class	
GO:0003811	biolink:NamedThing	obsolete complement activity	OBSOLETE. Any of a set of activities involved in the complement cascade.	tmpzr1t_l9r_go_relaxed.owl	complement activity					This term was made obsolete because it refers to involvement in a biological process.	GO:0006956				True			molecular_function											owl:Class	
GO:0019790	biolink:NamedThing	obsolete ubiquitin-like hydrolase activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	ubiquitin-like hydrolase activity					This term was made obsolete because it cannot be determined what its intended meaning was, because the term name is not found in the literature.	GO:0019783				True			molecular_function											owl:Class	
GO:0005670	biolink:NamedThing	obsolete transcription-activating factor, 30kD	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	transcription-activating factor, 30kD			GO:0005669		This term was made obsolete because it represents a single gene product and not a complex.					True			cellular_component											owl:Class	
GO:0071733	biolink:NamedThing	obsolete transcriptional activation by promoter-enhancer looping	OBSOLETE. The formation and maintenance of DNA loops that juxtapose the promoter and enhancer regions of RNA polymerase II-transcribed genes and activate transcription from an RNA polymerase II promoter.	tmpzr1t_l9r_go_relaxed.owl	long-range enhancer-promoter communication	https://github.com/geneontology/go-ontology/issues/20204				This term was obsoleted because it was defined like a molecular function.	GO:0045893	mah	2010-03-19T02:01:19Z		True			biological_process											owl:Class	
GO:0035422	biolink:NamedThing	obsolete activation of MAPKKK activity involved in innate immune response	OBSOLETE. Any process that initiates the activity of the inactive enzyme MAP kinase kinase kinase in the context of an innate immune response, a defense response mediated by germline encoded components that directly recognize components of potential pathogens.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/18000				This term was obsoleted because it should be represented as a GO-CAM model.		bf	2010-03-29T01:27:38Z		True			biological_process											owl:Class	
GO:0052536	biolink:NamedThing	obsolete positive regulation by organism of systemic acquired resistance in symbiont	OBSOLETE. Any process by which an organism activates, maintains or increases the frequency, rate or extent of systemic acquired resistance in the symbiont organism; systemic acquired resistance is a salicylic acid-mediated response that confers broad spectrum systemic resistance. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	positive regulation by organism of systemic acquired resistance in symbiont					This term was made obsolete because it does not represent a real biological process.					True			biological_process											owl:Class	
GO:0051816	biolink:NamedThing	obsolete acquisition of nutrients from other organism during symbiotic interaction	OBSOLETE. The production of structures and/or molecules in an organism that are required for the acquisition and/or utilization of nutrients obtained from a second organism, where the two organisms are in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it represented an unnecessary grouping class.					True			biological_process											owl:Class	
GO:0030009	biolink:NamedThing	obsolete complement factor H activity	OBSOLETE. A cofactor for the serine protease complement factor I.	tmpzr1t_l9r_go_relaxed.owl	complement factor H activity					This term was made obsolete because it represents a gene product.	GO:0006956				True			molecular_function											owl:Class	
GO:0008573	biolink:NamedThing	obsolete peroxisome-assembly ATPase activity	OBSOLETE. Catalysis of the reaction: ATP + H2O = ADP + phosphate. ATP hydrolysis to import and assemble peroxisome components into the organelle.	tmpzr1t_l9r_go_relaxed.owl	peroxisome-assembly ATPase activity			GO:0016887		This term was made obsolete because it incorporates process information.	GO:0007031				True			molecular_function											owl:Class	
GO:0016582	biolink:NamedThing	obsolete non-covalent chromatin modification	OBSOLETE. The alteration of DNA or protein in chromatin by the non-covalent addition or removal of chemical groups.	tmpzr1t_l9r_go_relaxed.owl						This term was made obsolete because it was added in error; its usefulness is unclear.					True			biological_process											owl:Class	
GO:0030460	biolink:NamedThing	obsolete nuclear translocation of MAPK (mating sensu Fungi)	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	nuclear translocation of MAPK (mating sensu Fungi)			GO:0000750		This term was made obsolete because it is a gene product specific term.					True			biological_process											owl:Class	
GO:0015061	biolink:NamedThing	obsolete red-sensitive opsin	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	red-sensitive opsin					This term was made obsolete because it refers to a class of proteins.	GO:0009881|GO:0016918|GO:0046876|GO:0009585|GO:0007603|GO:0016021				True			molecular_function											owl:Class	
GO:0005182	biolink:NamedThing	obsolete lipopeptide hormone	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	lipopeptide hormone					This term was made obsolete because it describes a type of hormone rather than a molecular function.	GO:0005179				True			molecular_function											owl:Class	
GO:0021920	biolink:NamedThing	obsolete regulation of transcription from RNA polymerase II promoter involved in spinal cord association neuron specification	OBSOLETE. Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the commitment of neuronal precursors to association neurons in the dorsal spinal cord.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it represents a GO-CAM model.	GO:0021519|GO:0006357				True			biological_process											owl:Class	
GO:0030602	biolink:NamedThing	obsolete chymosin activity	OBSOLETE. Catalysis of the lysis of peptide bonds with broad specificity similar to that of pepsin A. Clots milk by cleavage of a single Ser-Phe-l-Met-Ala bond in kappa-casein.	tmpzr1t_l9r_go_relaxed.owl	rennin|chymosin activity|rennin (but this should be avoided since it leads to confusion with renin)			GO:0004190		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0045331	biolink:NamedThing	obsolete coenzyme-M-7-mercaptoheptanoylthreonine-phosphate-heterodisulfide hydrogenase activity	OBSOLETE. Catalysis of the reaction: coenzyme-M 7-mercaptoheptanoylthreonine-phosphate heterodisulfide + H2 = coenzyme-M + N-(7-mercaptoheptanoyl)threonine O3-phosphate.	tmpzr1t_l9r_go_relaxed.owl	coenzyme-M-7-mercaptoheptanoylthreonine-phosphate-heterodisulphide hydrogenase activity|heterodisulfide reductase activity|coenzyme-M-7-mercaptoheptanoylthreonine-phosphate-heterodisulfide hydrogenase activity					This term was made obsolete because it represents two activities.	GO:0051912|GO:0051911				True			molecular_function											owl:Class	
GO:0035465	biolink:NamedThing	obsolete regulation of transforming growth factor beta receptor signaling pathway involved in determination of lateral mesoderm left/right asymmetry	OBSOLETE. Any process that modulates the frequency, rate or extent of activity of any TGF-beta receptor signaling pathway that is involved in the determination of the lateral plate mesoderm with respect to its left and right halves.	tmpzr1t_l9r_go_relaxed.owl	regulation of transforming growth factor beta receptor signalling pathway involved in determination of lateral mesoderm left/right asymmetry|regulation of TGFbeta receptor signaling pathway involved in determination of lateral mesoderm left/right asymmetry|regulation of TGF-beta receptor signaling pathway involved in determination of lateral mesoderm left/right asymmetry|regulation of TGFbeta receptor signalling pathway involved in determination of lateral mesoderm left/right asymmetry|regulation of transforming growth factor beta receptor signaling pathway involved in determination of lateral mesoderm left/right asymmetry|regulation of TGF-beta receptor signalling pathway involved in determination of lateral mesoderm left/right asymmetry			GO:1900175		This term was made obsolete because it describes regulation of the nodal signaling pathway. Nodal proteins are members of the TGF-beta superfamily, but are distinct from TGF-beta proteins themselves. TGF-beta proteins are not currently known to regulate left/right asymmetry in the lateral mesoderm.		bf	2010-04-19T01:36:23Z		True			biological_process											owl:Class	
GO:0052245	biolink:NamedThing	obsolete negative energy taxis on or near other organism involved in symbiotic interaction	OBSOLETE. The directed movement of a motile cell or organism on or near a second organism towards a lower level of a physical stimulus involved in energy generation, such as light, oxygen, and oxidizable substrates, where the two organisms are in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	negative energy taxis on or near other organism during symbiotic interaction	https://github.com/geneontology/go-ontology/issues/18819				This term was obsoleted because it represents both a process and a location.					True			biological_process											owl:Class	
GO:0070868	biolink:NamedThing	obsolete heterochromatin organization involved in chromatin silencing	OBSOLETE. Any process that results in the specification, formation or maintenance of the physical structure of eukaryotic heterochromatin and contributes to chromatin silencing.	tmpzr1t_l9r_go_relaxed.owl	heterochromatin organisation involved in chromatin silencing	https://github.com/geneontology/go-ontology/issues/22046				This term was obsoleted because it was not clearly defined, and used incorrectly.		mah	2009-08-20T12:45:52Z		True			biological_process											owl:Class	
GO:1905878	biolink:NamedThing	obsolete invadopodium disassembly	OBSOLETE. The disaggregation of an invadopodium into its constituent components.	tmpzr1t_l9r_go_relaxed.owl						This term was made obsolete because an invadopodium is an abnormal structure found in cancerous or transformed cells that is out of scope of GO.		sl	2017-01-27T20:44:16Z		True			biological_process											owl:Class	
GO:0100057	biolink:NamedThing	obsolete regulation of phenotypic switching by transcription from RNA polymerase II promoter	OBSOLETE. Any transcription from RNA polymerase II promoter process that regulates phenotypic switching.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it represents a GO-CAM model.		cjm	2015-04-02T04:13:19Z		True			biological_process											owl:Class	
GO:0060850	biolink:NamedThing	obsolete regulation of transcription involved in cell fate commitment	OBSOLETE. Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the commitment of a cell to a specific fate.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it represents a GO-CAM model.	GO:0045165|GO:0006357	dph	2009-08-12T11:40:09Z		True			biological_process											owl:Class	
GO:0110133	biolink:NamedThing	obsolete negative regulation of CRISPR-cas system	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of a CRISPR-cas system.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/16423				This term was obsoleted because it does not accurately capture the process described in the literature.	GO:0098672	kmv	2018-11-14T17:23:07Z		True			biological_process											owl:Class	
GO:0015560	biolink:NamedThing	obsolete L-idonate/D-gluconate:hydrogen symporter activity	OBSOLETE. Catalysis of the reaction: (L-idonate or D-gluconate)(out) + H+(out) = (L-iodonate or D-gluconate)(in) + H+(in).	tmpzr1t_l9r_go_relaxed.owl	L-idonate/D-gluconate:hydrogen symporter activity|L-idonate/D-gluconate:proton symporter					This term was made obsolete because it represents a multifunctional gene product.	GO:0015295|GO:0015128|GO:0015568				True			molecular_function											owl:Class	
GO:0006328	biolink:NamedThing	obsolete AT binding	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	AT binding			GO:0003680		This term was made obsolete because it represents a molecular function and not a biological process.					True			biological_process											owl:Class	
GO:0005733	biolink:NamedThing	obsolete small nucleolar RNA	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	small nucleolar RNA|snoRNA					This term was made obsolete because it represents a gene product.					True			cellular_component											owl:Class	
GO:0052033	biolink:NamedThing	obsolete pathogen-associated molecular pattern dependent induction by symbiont of host innate immune response	OBSOLETE. Any process that involves recognition of a pathogen-associated molecular pattern, and by which an organism activates, maintains or increases the frequency, rate or extent of the innate immune response of the host organism; the innate immune response is the host's first line of defense against infection. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	PTI|MAMP dependent induction of host innate immunity|PAMP dependent induction of host innate immunity|general elicitor-dependent induction of host innate immunity|MAMP dependent activation of host innate immunity|PAMP dependent activation of host innate immunity|pattern-triggered immunity|pathogen-associated molecular pattern dependent activation by organism of host innate immunity|pathogen-associated molecular pattern dependent induction by symbiont of host innate immunity|general elicitor-dependent activation of host innate immunity					This term was obsoleted because it has been misused.	GO:0002752|GO:0052034|GO:0002221				True			biological_process											owl:Class	
GO:0019039	biolink:NamedThing	obsolete viral-cell fusion molecule activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	viral-cell fusion molecule activity					This term was made obsolete because it represents a gene product.	GO:0019064|GO:0050839				True			molecular_function											owl:Class	
GO:0008985	biolink:NamedThing	obsolete pyruvate dehydrogenase (cytochrome) activity	OBSOLETE. Catalysis of the reaction: pyruvate + ferricytochrome b1 + H2O = CO2 + acetate + ferrocytochrome b1.	tmpzr1t_l9r_go_relaxed.owl	pyruvate:ubiquinone-8-oxidoreductase activity|pyruvate:ferricytochrome-b1 oxidoreductase activity|pyruvate dehydrogenase (cytochrome) activity|pyruvic (cytochrome b1) dehydrogenase activity			GO:0052737		This term was made obsolete because the EC activity it represents, EC:1.2.2.2, has been deleted.					True			molecular_function											owl:Class	
GO:0047138	biolink:NamedThing	obsolete aquacobalamin reductase activity	OBSOLETE. Catalysis of the reaction: 2 cob(II)alamin + NAD+ = 2 aquacob(III)alamin + NADH + H+.	tmpzr1t_l9r_go_relaxed.owl	NADH-linked aquacobalamin reductase activity|B(12a) reductase activity|NADH:cob(III)alamin oxidoreductase activity|vitamin B12a reductase activity|NADH2:cob(III)alamin oxidoreductase activity|cob(II)alamin:NAD+ oxidoreductase activity|aquocobalamin reductase activity|vitamin B(12a) reductase activity|B12a reductase activity	https://github.com/geneontology/go-ontology/issues/20679			EC:1.16.1.3|MetaCyc:AQUACOBALAMIN-REDUCTASE-RXN	The term was obsoleted because it is not known to be catalyzed by any gene product.					True			molecular_function											owl:Class	
GO:0001028	biolink:NamedThing	obsolete RNA polymerase III type 2 promoter TFIIIB-type transcription factor activity	OBSOLETE. Binding to an RNA polymerase III (Pol III) complex, typically composed of seventeen subunits, and with another protein, macromolecule, or complex, permitting those molecules to function in a coordinated way. Once recruited to an RNA polymerase III type 2 promoter by a TFIIIC-type factor, binds to DNA, recruits RNA polymerase III and facilitates the transition from the closed to the open complex.	tmpzr1t_l9r_go_relaxed.owl	RNA polymerase III type 2 promoter polymerase recruiting transcription factor activity					The reason for obsoletion is that there is a single TFIIIB activity; this is not dependent on the promoter.		krc	2010-08-23T12:52:01Z		True			molecular_function											owl:Class	
GO:0015336	biolink:NamedThing	obsolete high affinity metal ion uptake transporter activity	OBSOLETE. Catalysis of the reaction: Me2+(out) + H+(out) = Me2+(in) + H+(in). Me can be Fe2+, Mn2+, Zn2+, Cu2+, Cd2+, Ni2+ or Co2+.	tmpzr1t_l9r_go_relaxed.owl	high affinity metal ion uptake transporter activity					This term was made obsolete because it represents a gene product and not a molecular function.	GO:0046873|GO:0015295				True			molecular_function											owl:Class	
GO:0015332	biolink:NamedThing	obsolete leucine/valine/isoleucine permease activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	leucine/valine/isoleucine permease activity					This term was made obsolete because it represents a multifunctional gene product.	GO:0015190|GO:0005304|GO:0022857|GO:0015188				True			molecular_function											owl:Class	
GO:0004327	biolink:NamedThing	obsolete formaldehyde dehydrogenase (glutathione) activity	OBSOLETE. Catalysis of the reaction: formaldehyde + glutathione + NAD+ = S-formylglutathione + NADH + H+.	tmpzr1t_l9r_go_relaxed.owl	formaldehyde dehydrogenase (glutathione) activity					This term was made obsolete because it was derived from an EC entry (1.2.1.1) that has since been split into two entries.	GO:0051903|GO:0051907				True			molecular_function											owl:Class	
GO:0051789	biolink:NamedThing	obsolete response to protein	OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a protein stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to protein stimulus|response to protein					This term was made obsolete because more specific terms exist.	GO:0034097|GO:0051788|GO:0009725|GO:0070848|GO:0006986				True			biological_process											owl:Class	
GO:0085013	biolink:NamedThing	obsolete interaction with host via protein secreted by type VII secretion system	OBSOLETE. An interaction with the host organism mediated by a substance secreted by the symbiont organism by a type VII secretion system. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it conflated the process in which a gene product is involved with the secretion system by which it reaches its target.		jl	2010-02-10T03:31:07Z		True			biological_process											owl:Class	
GO:0004215	biolink:NamedThing	obsolete cathepsin H activity	OBSOLETE. Catalysis of the hydrolysis of peptide bonds, acting as an aminopeptidase (notably, cleaving Arg-Xaa bonds) as well as an endopeptidase.	tmpzr1t_l9r_go_relaxed.owl	cathepsin BA activity|cathepsin Ba|benzoylarginine-naphthylamide (BANA) hydrolase activity|cathepsin H activity|N-benzoylarginine-beta-naphthylamide hydrolase activity|aleurain activity|cathepsin B3 activity			GO:0004197		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0030444	biolink:NamedThing	obsolete microtubule depolymerization during nuclear congression	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	microtubule depolymerization during nuclear congression			GO:0007019		This term was made obsolete because the entire branch of the ontology was changed.					True			biological_process											owl:Class	
GO:0005541	biolink:NamedThing	obsolete acyl-CoA or acyl binding	OBSOLETE. Interacting selectively with acyl-CoA or acyl, any derivative of coenzyme A in which the sulfhydryl group is in thiolester linkage with a fatty acyl group, or any group formally derived by removal of a hydroxyl group from the acid function of an organic acid.	tmpzr1t_l9r_go_relaxed.owl	acyl-CoA or acyl binding					This term was made obsolete because it was replaced by more appropriate terms.	GO:0000062|GO:0000035				True			molecular_function											owl:Class	
GO:0052355	biolink:NamedThing	obsolete catabolism by host of symbiont cell wall cellulose	OBSOLETE. The chemical reactions and pathways performed by an organism resulting in the breakdown of cellulose in the symbiont cell wall. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/21469				This term was obsoleted because it represents a molecular function.					True			biological_process											owl:Class	
GO:0030189	biolink:NamedThing	obsolete chaperone activator activity	OBSOLETE. Increases the activity of a molecular chaperone.	tmpzr1t_l9r_go_relaxed.owl	chaperone activator activity					This term was made obsolete because it refers to a obsolete molecular function term, 'chaperone activity'.	GO:0051787|GO:0006457|GO:0051082				True			molecular_function											owl:Class	
GO:0006439	biolink:NamedThing	obsolete aminoacyl-tRNA hydrolase reaction	OBSOLETE. Hydrolysis of the peptidyl-tRNA by aminoacyl-tRNA hydrolase upon termination of translation. Analogous to usual peptidyl transfer during elongation, except that the acceptor is H2O instead of an aminoacyl-tRNA.	tmpzr1t_l9r_go_relaxed.owl	aminoacyl-tRNA hydrolase reaction			GO:0004045		This term was made obsolete because it represents a molecular function.					True			biological_process											owl:Class	
GO:0001310	biolink:NamedThing	obsolete extrachromosomal rDNA circle accumulation involved in replicative cell aging	OBSOLETE. Increase in abundance of circular DNA molecules containing ribosomal DNA repeats in dividing cells as they age. These molecules originate in the chromosome but are excised and circularized, often by intramolecular homologous recombination between direct tandem repeats, and then replicated independently of chromosomal replication.	tmpzr1t_l9r_go_relaxed.owl	extrachromosomal rDNA circle accumulation during replicative cell aging|extrachromosomal ribosomal DNA circle accumulation during replicative cell aging|extrachromosomal rDNA circle accumulation during replicative cell ageing	https://github.com/geneontology/go-ontology/issues/20007				This term was obsoleted because it represents an assay, not a true biological process.					True			biological_process											owl:Class	
GO:0035986	biolink:NamedThing	obsolete senescence-associated heterochromatin focus assembly	OBSOLETE. The assembly of chromatin into senescence-associated heterochromatin foci (SAHF), transcriptionally-silent heterochromatin structures present in senescent cells, containing the condensed chromatin of one chromosome, and enriched for histone modifications. Formation of these chromatin structures is thought to repress expression of proliferation-promoting genes.	tmpzr1t_l9r_go_relaxed.owl	senescence-associated heterochromatin focus formation|SAHF formation|senescence-associated heterochromatin foci formation	https://github.com/geneontology/go-ontology/issues/22024				This term was obsoleted because there is no evidence that this is a distinct process; this should be captured as an extension	GO:0031507	bf	2011-08-25T04:43:56Z		True			biological_process											owl:Class	
GO:0033903	biolink:NamedThing	obsolete endo-1,3(4)-beta-glucanase activity	OBSOLETE. Catalysis of the endohydrolysis of 1,3- or 1,4-linkages in beta-D-glucans when the glucose residue whose reducing group is involved in the linkage to be hydrolysed is itself substituted at C-3.	tmpzr1t_l9r_go_relaxed.owl	beta-1,3-glucanase activity|endo-1,3-1,4-beta-D-glucanase activity|endo-beta-(1,3)-D-glucanase activity|endo-beta-1,3-1,4-glucanase activity|endo-1,3(4)-beta-glucanase activity|endo-beta-1,3-glucanase IV activity|laminaranase activity|beta-1,3-1,4-glucanase activity|endo-1,4-beta-glucanase activity|endo-1,3-beta-glucanase activity|1,3-(1,3;1,4)-beta-D-glucan 3(4)-glucanohydrolase activity|laminarinase activity|endo-beta-(1->3)-D-glucanase activity|endo-beta-1,3(4)-glucanase activity|endo-1,3-beta-D-glucanase activity				EC:3.2.1.6|MetaCyc:3.2.1.6-RXN	This term was made obsolete because it was representing two different activities, for which new GO terms have now been created: GO:0052861 glucan endo-1,3-beta-glucanase activity, C-3 substituted reducing group and GO:0052862 glucan endo-1,4-beta-glucanase activity, C-3 substituted reducing group.	GO:0052861|GO:0052862				True			molecular_function											owl:Class	
GO:0008845	biolink:NamedThing	obsolete endonuclease VIII activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	endonuclease VIII activity					This term was made obsolete because it represents a gene product.	GO:0003684|GO:0003906|GO:0000703|GO:0019104|GO:0004519|GO:0008081				True			molecular_function											owl:Class	
GO:0052340	biolink:NamedThing	obsolete catabolism by organism of cell wall cellulose in other organism involved in symbiotic interaction	OBSOLETE. The chemical reactions and pathways performed by an organism resulting in the breakdown of cellulose in the cell wall of a second organism, where the two organisms are in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	catabolism by organism of cell wall cellulose in other organism during symbiotic interaction	https://github.com/geneontology/go-ontology/issues/21396				This term was obsoleted because it represents an unnecessary grouping class.					True			biological_process											owl:Class	
GO:0008950	biolink:NamedThing	obsolete p-aminobenzoate synthetase	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	p-aminobenzoate synthetase					This term was made obsolete because it refers to two different functions, a glutamine amidotransferase that functions as an aminodeoxychorismate synthase [itself composed of two enzymatic activities, a glutaminase and a chorismate aminase (this latter is sometimes referred to as the aminodeoxychorismate synthase)] and a 4-amino-4-deoxychorismate aromatase (4-amino-4-deoxychorismate lyase). Note that the name 'para-amino benzoate synthase' was initially given to the 'aminodeoxychorismate synthase' activity before the additional lyase activity was discovered.	GO:0046820|GO:0008696				True			molecular_function											owl:Class	
GO:0044037	biolink:NamedThing	obsolete multi-organism cell wall macromolecule metabolic process	OBSOLETE. The chemical reactions and pathways involving macromolecules forming, or destined to form, part of a cell wall, involving more than one organism. A cell wall is a rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells, maintaining their shape and protecting them from osmotic lysis.	tmpzr1t_l9r_go_relaxed.owl	multi-organism cell wall macromolecule metabolism	https://github.com/geneontology/go-ontology/issues/19769				This term was obsoleted because there is no evidence that this process exists.					True			biological_process											owl:Class	
GO:1905565	biolink:NamedThing	obsolete regulation of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport	OBSOLETE. Any process that modulates the frequency, rate or extent of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport.	tmpzr1t_l9r_go_relaxed.owl	regulation of receptor-mediated endocytosis of low-density lipoprotein involved in cholesterol transport|regulation of receptor-mediated endocytosis of LDL					This term was obsoleted at the TermGenie Gatekeeper stage.		nc	2016-10-18T10:58:29Z		True			biological_process											owl:Class	
GO:0006131	biolink:NamedThing	obsolete dihydrolipoamide reduction	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	dihydrolipoamide reduction					This term was made obsolete because it represents a molecular function rather than a biological process.	GO:0022900|GO:0004148|GO:0051068				True			biological_process											owl:Class	
GO:0007048	biolink:NamedThing	obsolete oncogenesis	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	oncogenesis					This term was made obsolete because it represents a pathological process.					True			biological_process											owl:Class	
GO:0005623	biolink:NamedThing	obsolete cell	OBSOLETE. The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/19036	cell and encapsulating structures		NIF_Subcellular:sao1813327414|Wikipedia:Cell_(biology)	This term was obsoleted because it was redundant with the root class of the cell ontology, CL:0000000.					True			cellular_component											owl:Class	
GO:0017092	biolink:NamedThing	obsolete sterol regulatory element-binding protein site 2 protease activity	OBSOLETE. Catalysis of the cleavage, within the membrane-spanning helix, of the amino-terminal half (the intermediate form) of sterol regulatory element binding protein (SREBP). This activity releases the transcription factor domain of SREBP from the membrane, freeing it to enter the nucleus.	tmpzr1t_l9r_go_relaxed.owl	SREBP site 2 protease activity|sterol regulatory element-binding protein site 2 protease activity			GO:0008237		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0009417	biolink:NamedThing	obsolete fimbrin	OBSOLETE. A class of proteins that are the subunit components of fimbria.	tmpzr1t_l9r_go_relaxed.owl	fimbrin			GO:0009289		This term was made obsolete because it represents a class of gene products.					True			cellular_component											owl:Class	
GO:0004194	biolink:NamedThing	obsolete pepsin A activity	OBSOLETE. Catalysis of the hydrolysis of peptide bonds. Preferential cleavage: hydrophobic, preferably aromatic, residues in P1 and P1' positions. Cleaves Phe1-Val2, Gln4-His5, Glu13-Ala14, Ala14-Leu15, Leu15-Tyr16, Tyr16-Leu17, Gly23-Phe24, Phe24-Phe25 and Phe25-Tyr26 bonds in the B chain of insulin.	tmpzr1t_l9r_go_relaxed.owl	lactated pepsin|P II|pepsin activity|pepsin R|pepsin fortior|lactated pepsin elixir|P I|pepsin D|elixir lactate of pepsin|fundus-pepsin|pepsin A activity			GO:0004190		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0043736	biolink:NamedThing	obsolete DNA-3-methyladenine glycosylase IV activity	OBSOLETE. Catalysis of the hydrolysis of alkylated DNA; recognizes and removes both N-3- and N-7-methyl purines by cleaving the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar. The reaction releases a free base and leaves an apurinic (AP) site.	tmpzr1t_l9r_go_relaxed.owl	DNA-3-methyladenine glycosylase IV activity|MpgII|Mpg II					This term was made obsolete because it represents an enzyme with four different activities.	GO:0052822|GO:0008725|GO:0043916|GO:0052821				True			molecular_function											owl:Class	
GO:0075103	biolink:NamedThing	obsolete modulation by host of symbiont calcium or calmodulin-mediated signal transduction	OBSOLETE. Any process in which the host organism modulates the frequency, rate or extent of calcium or calmodulin-mediated signal transduction in the symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	modulation by host of symbiont Ca++ or calmodulin-mediated signal transduction					The reason for obsoletion is that there is no evidence that the host can modulate or regulate a symbiont's signal transduction pathway.					True			biological_process											owl:Class	
GO:0016148	biolink:NamedThing	obsolete protein-synthesizing GTPase activity, termination	OBSOLETE. Catalysis of the reaction: GTP + H2O = GDP + phosphate.	tmpzr1t_l9r_go_relaxed.owl	protein-synthesizing GTPase activity, termination					This term was made obsolete because it contains both process and function information.	GO:0006415|GO:0003924|GO:0008079|GO:0006412				True			molecular_function											owl:Class	
GO:0004384	biolink:NamedThing	obsolete membrane-associated guanylate kinase	OBSOLETE. Catalysis of the reaction: ATP + GMP = ADP + GDP, associated with the cell membrane.	tmpzr1t_l9r_go_relaxed.owl	membrane-associated guanylate kinase|MAGUK					This term was made obsolete because it represents a gene product and not a function.	GO:0007155|GO:0004385|GO:0050839|GO:0016021|GO:0005102				True			molecular_function											owl:Class	
GO:0015051	biolink:NamedThing	obsolete X-opioid receptor activity	OBSOLETE. Combining with an opioid to initiate a change in cell activity, with the pharmacological characteristics of X-opioid receptors.	tmpzr1t_l9r_go_relaxed.owl	X-opioid receptor activity					This term was made obsolete because the receptor is defined based on its pharmacological properties.	GO:0001626				True			molecular_function											owl:Class	
GO:0048151	biolink:NamedThing	obsolete hyperphosphorylation	OBSOLETE. The excessive phosphorylation of a protein, as a result of activation of kinases, deactivation of phosphatases, or both.	tmpzr1t_l9r_go_relaxed.owl	hyperphosphorylation			GO:0016310		This term was made obsolete because it is an unnecessary grouping term and was poorly defined.					True			biological_process											owl:Class	
GO:1990881	biolink:NamedThing	obsolete negative regulation of transcription from RNA polymerase II promoter in response to DNA damage	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of DNA damage.	tmpzr1t_l9r_go_relaxed.owl	inhibition of transcription from RNA polymerase II promoter in response to DNA damage|down-regulation of transcription from RNA polymerase II promoter in response to DNA damage|down regulation of transcription from RNA polymerase II promoter in response to DNA damage|downregulation of transcription from RNA polymerase II promoter in response to DNA damage					This term was obsoleted at the TermGenie Gatekeeper stage.	GO:0006974|GO:0000122	mcc	2015-10-28T13:02:18Z		True			biological_process											owl:Class	
GO:0018443	biolink:NamedThing	obsolete enzyme active site formation via L-aspartic 4-phosphoric anhydride	OBSOLETE. The transient phosphorylation of peptidyl-aspartic acid to form L-aspartic 4-phosphoric anhydride.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/15594			RESID:AA0033	This term was obsoleted because it represents a reaction intermediate, not a biological process, see PMID:4357737.					True			biological_process											owl:Class	
GO:0052522	biolink:NamedThing	obsolete positive regulation by organism of phagocytosis in other organism involved in symbiotic interaction	OBSOLETE. Any process in which an organism activates, maintains or increases the frequency, rate or extent of phagocytosis, the engulfing by phagocytes of external particulate material, in the second organism, where the two organisms are in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	upregulation by organism of phagocytosis in other organism during symbiotic interaction|positive regulation by organism of phagocytosis in other organism during symbiotic interaction|up regulation by organism of phagocytosis in other organism during symbiotic interaction|up-regulation by organism of phagocytosis in other organism during symbiotic interaction|activation by organism of phagocytosis in other organism during symbiotic interaction|stimulation by organism of phagocytosis in other organism during symbiotic interaction	https://github.com/geneontology/go-ontology/issues/18562				This term was obsoleted because there is no evidence that this process exists.					True			biological_process											owl:Class	
GO:0075106	biolink:NamedThing	obsolete modulation by symbiont of host adenylate cyclase activity	OBSOLETE. Any process in which the symbiont modulates the frequency, rate or extent of the host adenylate cyclase activity, which involves catalysis of the reaction: ATP = 3',5'-cyclic AMP + diphosphate. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	Modulation by symbiont of host adenyl cyclase activity|Modulation by symbiont of host cAMP generating peptide activity|Modulation by symbiont of host ATP pyrophosphate-lyase activity|Modulation by symbiont of host ATP diphosphate-lyase (cyclizing ; 3',5'-cyclic-AMP-forming) activity|Modulation by symbiont of host adenylyl cyclase activity|Modulation by symbiont of host adenylylcyclase activity|Modulation by symbiont of host ATP diphosphate-lyase (cyclizing) activity|Modulation by symbiont of host 3',5'-cyclic AMP synthetase activity	https://github.com/geneontology/go-ontology/issues/21740				This term was obsoleted because it represents a molecular function.					True			biological_process											owl:Class	
GO:0042280	biolink:NamedThing	obsolete cell surface antigen activity, host-interacting	OBSOLETE. Functions as an immunogenic target for the host immune system that masks other invariant surface molecules from immune recognition.	tmpzr1t_l9r_go_relaxed.owl	cell surface antigen activity, host-interacting					This term was made obsolete because describing something as an 'antigen' means that an organism can produce antibodies to it, which says nothing about the gene product activity.	GO:0044403|GO:0046789				True			molecular_function											owl:Class	
GO:0008041	biolink:NamedThing	obsolete storage protein of fat body (sensu Insecta)	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	storage protein of fat body (sensu Insecta)			GO:0045735		This term was made obsolete because it describes a cellular location rather than a function.					True			molecular_function											owl:Class	
GO:0005050	biolink:NamedThing	obsolete peroxisome receptor	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	peroxisome receptor					This term was made obsolete because it describes a cellular component.	GO:0038023|GO:0005777				True			molecular_function											owl:Class	
GO:0005799	biolink:NamedThing	obsolete coatomer	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	coatomer|COPI vesicle					This term was made obsolete because its position and synonym implied that it confused a coated vesicle with the coat itself.	GO:0030126|GO:0030137				True			cellular_component											owl:Class	
GO:0005205	biolink:NamedThing	obsolete chondroitin sulfate/dermatan sulfate proteoglycan	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	chondroitin sulphate/dermatan sulphate proteoglycan|chondroitin sulfate/dermatan sulfate proteoglycan					This term was made obsolete because it describes the composition (i.e. proteoglycan) of a gene product, not a molecular function.					True			molecular_function											owl:Class	
GO:0016265	biolink:NamedThing	obsolete death	OBSOLETE. A permanent cessation of all vital functions: the end of life; can be applied to a whole organism or to a part of an organism.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Death	This term was made obsolete because it refers to a phenotype. When death of a cell or tissue is a result of a true biological process, this should be captured using 'programmed cell death' or one of its descendants.	GO:0012501|GO:0008219				True			biological_process											owl:Class	
GO:1901043	biolink:NamedThing	obsolete protein polyubiquitination involved in cellular response to misfolded protein	OBSOLETE. Any protein polyubiquitination that is involved in cellular response to misfolded protein.	tmpzr1t_l9r_go_relaxed.owl	protein polyubiquitylation of cellular response to misfolded protein|polyubiquitin of cellular response to misfolded protein|protein polyubiquitination involved in cellular response to misfolded protein|protein polyubiquitinylation of cellular response to misfolded protein|protein polyubiquitination of cellular response to misfolded protein					This term was made obsolete because it was added in error and a more specific term was created.	GO:1901044	al	2012-06-26T09:40:45Z		True			biological_process											owl:Class	
GO:0005817	biolink:NamedThing	obsolete centrosomal mitotic factor	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	centrosomal mitotic factor					This term was made obsolete because it was not defined.					True			cellular_component											owl:Class	
GO:1903156	biolink:NamedThing	obsolete guanine transmembrane transporter activity involved in guanine import into cell	OBSOLETE. Any guanine transmembrane transporter activity that is involved in guanine import into cell.	tmpzr1t_l9r_go_relaxed.owl	guanine transmembrane transporter activity involved in guanine import into cell					This term was obsoleted at the TermGenie Gatekeeper stage.		dos	2014-07-09T11:56:10Z		True			molecular_function											owl:Class	
GO:0009460	biolink:NamedThing	obsolete cytochrome b	OBSOLETE. A cytochrome containing noncovalently bound protoheme (iron protoporphyrin IX; heme b).	tmpzr1t_l9r_go_relaxed.owl	cytochrome b					This term was made obsolete because it represents a gene product.	GO:0009055				True			molecular_function											owl:Class	
GO:0001636	biolink:NamedThing	obsolete corticotrophin-releasing factor gastric inhibitory peptide-like receptor activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	corticotrophin-releasing factor gastric inhibitory peptide-like receptor activity					This term was made obsolete because it represents a gene product, was not defined, and is named based on protein features.					True			molecular_function											owl:Class	
GO:0000188	biolink:NamedThing	obsolete inactivation of MAPK activity	OBSOLETE. Any process that terminates the activity of the active enzyme MAP kinase.	tmpzr1t_l9r_go_relaxed.owl	inactivation of MAPK during sporulation|termination of MAPK activity	https://github.com/geneontology/go-ontology/issues/21308				This term was obsoleted because it represents a molecular function.	GO:0000165|GO:0043539				True			biological_process											owl:Class	
GO:0071686	biolink:NamedThing	obsolete horsetail nucleus	OBSOLETE. The elongated nucleus which forms during the rapid oscillatory movement at meiotic prophase; characterized in Schizosaccharomyces pombe.	tmpzr1t_l9r_go_relaxed.owl						This term was made obsolete at the request of PomBase as the concept can be expressed by annotating to a less granular term and using annotation extensions.		mah	2010-02-22T04:52:01Z		True			cellular_component											owl:Class	
GO:0055101	biolink:NamedThing	obsolete glycerophospholipase inhibitor activity	OBSOLETE. Stops, prevents or reduces the activity of a glycerophospholipase, an enzyme that catalyzes of the hydrolysis of a glycerophospholipid.	tmpzr1t_l9r_go_relaxed.owl	glycerophospholipase inhibitor activity					This term was made obsolete because it refers to a non-existent molecular function term, 'glycerophosphate activity', which also cannot be found in the literature.					True			molecular_function											owl:Class	
GO:0001630	biolink:NamedThing	obsolete GP40-like receptor activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	GP40-like receptor activity					This term was made obsolete because it represents a gene product, was not defined, and is named based on protein features.					True			molecular_function											owl:Class	
GO:0005781	biolink:NamedThing	obsolete peroxisome targeting signal receptor complex	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	peroxisome targeting signal receptor complex					This term was made obsolete because it represents a single polypeptide rather than a complex; all known peroxisome targeting signal receptors are monomeric.	GO:0000268|GO:0006625				True			cellular_component											owl:Class	
GO:0004009	biolink:NamedThing	obsolete ATP-binding cassette (ABC) transporter activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	ATP-binding cassette (ABC) transporter activity					This term was made obsolete because ABC transporters are a protein family rather than a functional grouping.	GO:0043190|GO:0042626				True			molecular_function											owl:Class	
GO:1990843	biolink:NamedThing	obsolete subsarcolemmal mitochondrion	OBSOLETE. A mitochondrion that occurs adjacent to the sarcolemma in striated muscle cells and responds in distinct ways to physiological triggers.	tmpzr1t_l9r_go_relaxed.owl	SSM|SS mitochondrion					This term was obsoleted because it corresponds to mitochondria of specific cell types and this information should be captured as an extension.	GO:0005739	sl	2015-08-31T16:05:14Z		True			cellular_component											owl:Class	
GO:0008259	biolink:NamedThing	obsolete transforming growth factor beta ligand binding to type I receptor	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	TGFbeta ligand binding to type I receptor|TGF-beta ligand binding to type I receptor|transforming growth factor beta ligand binding to type I receptor					This term was made obsolete because it represents a function.	GO:0005025|GO:0005160|GO:0050431				True			biological_process											owl:Class	
GO:1900201	biolink:NamedThing	obsolete regulation of spread of virus in host, cell to cell	OBSOLETE. Any process that modulates the frequency, rate or extent of spread of virus in host, cell to cell.	tmpzr1t_l9r_go_relaxed.owl	regulation of spread of virus within host, cell to cell|regulation of spread of virus in host, cell to cell|regulation of cell to cell spread of virus within host|regulation of viral spread within host, cell to cell					This term was obsoleted at the TermGenie Gatekeeper stage.		pm	2012-03-21T01:15:41Z		True			biological_process											owl:Class	
GO:0075147	biolink:NamedThing	obsolete regulation of signal transduction in response to host	OBSOLETE. Any process in which the symbiont organism modulates the frequency, rate or extent of its signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	regulation of symbiont signal transduction in response to host					This term was obsoleted because there is no evidence that this process exists.					True			biological_process											owl:Class	
GO:0007239	biolink:NamedThing	obsolete activation of Hog1	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	activation of Hog1					This term was made obsolete because it contains gene product and species specific information.					True			biological_process											owl:Class	
GO:2000575	biolink:NamedThing	obsolete negative regulation of microtubule motor activity	OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of microtubule motor activity.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of dynein ATPase activity|negative regulation of kinetochore motor activity|negative regulation of kinesin motor activity|negative regulation of axonemal motor activity|negative regulation of kinesin|negative regulation of dynein	https://github.com/geneontology/go-ontology/issues/21626				This term was obsoleted because it represents a molecular function.	GO:0140661	bf	2011-04-05T08:36:48Z		True			biological_process											owl:Class	
GO:0044047	biolink:NamedThing	obsolete interaction with host via protein secreted by type I secretion system	OBSOLETE. An interaction with the host organism mediated by a substance secreted by the other (symbiont) organism via a type I secretion system. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it conflated the process in which a gene product is involved with the secretion system by which it reaches its target.					True			biological_process											owl:Class	
RO:0002405	biolink:NamedThing	immediately causally downstream of		tmpzr1t_l9r_go_relaxed.owl					RO:0002405									external									immediately_causally_downstream_of			
GO:0052436	biolink:NamedThing	obsolete modulation by organism of defense-related symbiont calcium-dependent protein kinase pathway	OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of the symbiont calcium-dependent protein kinase signal transduction pathways during the symbiont defense response. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	modulation by organism of defense-related symbiont CDPK pathway|modulation by organism of defense-related symbiont calcium-dependent protein kinase pathway					This term was made obsolete because it does not represent a real biological process.					True			biological_process											owl:Class	
GO:0003809	biolink:NamedThing	obsolete thrombin activity	OBSOLETE. Catalysis of the preferential cleavage of Arg-Gly; activates fibrinogen to fibrin and releases fibrinopeptide A and B.	tmpzr1t_l9r_go_relaxed.owl	thrombin activity|tropostasin|activated blood-coagulation factor II|thrombofort|fibrinogenase activity|gamma-thrombin|thrombin-C|topical|beta-thrombin|blood-coagulation factor IIa|E thrombin|thrombase activity|factor IIa			GO:0004252		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0100070	biolink:NamedThing	obsolete obsolete regulation of fatty acid biosynthetic process by transcription from RNA polymerase II promoter	OBSOLETE. Any transcription from RNA polymerase II promoter process that regulates fatty acid biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it represents a GO-CAM model.		cjm	2015-04-02T04:13:19Z		True			biological_process											owl:Class	
GO:0051389	biolink:NamedThing	obsolete inactivation of MAPKK activity	OBSOLETE. Any process that terminates the activity of the active enzyme MAP kinase kinase (MAPKK).	tmpzr1t_l9r_go_relaxed.owl	termination of MAP kinase kinase activity|inactivation of MAP kinase kinase activity|termination of MAPKK activity	https://github.com/geneontology/go-ontology/issues/21308				This term was obsoleted because it represents a molecular function.	GO:0030291|GO:0043409				True			biological_process											owl:Class	
GO:0016083	biolink:NamedThing	obsolete synaptic vesicle fusion	OBSOLETE. Fusion of the synaptic vesicle with the postsynaptic membrane.	tmpzr1t_l9r_go_relaxed.owl	synaptic vesicle fusion					This term was made obsolete because it was wrongly defined.	GO:0016192				True			biological_process											owl:Class	
GO:0004374	biolink:NamedThing	obsolete glycine cleavage system	OBSOLETE. Catalysis of the reactions: glycine + lipoylprotein = S-aminomethyldihydrolipoylprotein + carbon dioxide (CO2), followed by S-aminomethyldihydrolipoylprotein + (6S)-tetrahydrofolate = dihydrolipoylprotein + (6R)-5,10-methylenetetrahydrofolate + ammonia. Made up of two components, aminomethyltransferase and glycine dehydrogenase (decarboxylating).	tmpzr1t_l9r_go_relaxed.owl	glycine synthase|glycine cleavage system			GO:0019464		This term was made obsolete because it represents a process rather than a function.					True			molecular_function											owl:Class	
GO:0052049	biolink:NamedThing	obsolete interaction with host via protein secreted by type III secretion system	OBSOLETE. An interaction with the host organism mediated by a substance secreted by the symbiont organism by a type III secretion system. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it conflated the process in which a gene product is involved with the secretion system by which it reaches its target.					True			biological_process											owl:Class	
GO:0006803	biolink:NamedThing	obsolete glutathione conjugation reaction	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	glutathione conjugation reaction			GO:0004364		This term was made obsolete because it represents a molecular function and not a biological process.					True			biological_process											owl:Class	
GO:0071438	biolink:NamedThing	obsolete invadopodium membrane	OBSOLETE. The portion of the plasma membrane surrounding an invadopodium.	tmpzr1t_l9r_go_relaxed.owl						This term was made obsolete because an invadopodium is an abnormal structure found in cancerous or transformed cells that is out of scope of GO.		mah	2009-12-16T03:00:30Z		True			cellular_component											owl:Class	
GO:0051843	biolink:NamedThing	obsolete evasion or tolerance of symbiont defense response	OBSOLETE. Any process, either active or passive, by which an organism avoids or tolerates the effects of a symbiont organism's defense response. The symbiont defense response is mounted by the symbiont in response to the presence of the organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	evasion or tolerance of symbiont defense response|evasion of symbiont defence response					This term was made obsolete because it does not represent a real process that exists in nature.					True			biological_process											owl:Class	
GO:0043172	biolink:NamedThing	obsolete ferredoxin biosynthetic process	OBSOLETE. The chemical reactions and pathways resulting in the formation of ferredoxin, any simple, nonenzymatic iron-sulfur protein that is characterized by having equal numbers of atoms of iron and labile sulfur. Iron and sulfur atoms are present in one or two clusters of two or four atoms of each.	tmpzr1t_l9r_go_relaxed.owl	ferredoxin formation|ferredoxin anabolism|ferredoxin synthesis|ferredoxin biosynthesis					This term was made obsolete because it refers to biosynthesis of a protein.					True			biological_process											owl:Class	
GO:0052477	biolink:NamedThing	obsolete negative regulation by organism of defense-related symbiont callose deposition	OBSOLETE. Any process by which an organism stops, prevents, or reduces the frequency, rate or extent of callose deposition performed by the symbiont as part of its defense response. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	negative regulation by organism of defense-related symbiont callose deposition|suppression by organism of defense-related symbiont callose deposition					This term was made obsolete because it does not represent a real biological process.					True			biological_process											owl:Class	
GO:0035828	biolink:NamedThing	obsolete renal rubidium ion transport	OBSOLETE. The directed movement of rubidium ions (Rb+) by the kidney.	tmpzr1t_l9r_go_relaxed.owl	renal Rb+ transport|renal rubidium cation transport					This term has been obsoleted because it represents an assay, and not a physiological process.		bf	2011-05-04T02:58:50Z		True			biological_process											owl:Class	
GO:0001083	biolink:NamedThing	obsolete transcription factor activity, RNA polymerase II basal transcription factor binding	OBSOLETE. Binding to a basal RNA polymerase II transcription factor, which may be a single protein or a complex, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well.	tmpzr1t_l9r_go_relaxed.owl	RNA polymerase II basal transcription factor binding transcription factor activity					This term was obsoleted because it represents two separate functions. The corresponding 'binding' term should be used in combination with a transcription regulator activity child.		krc	2010-10-27T04:12:55Z		True			molecular_function											owl:Class	
GO:0042964	biolink:NamedThing	obsolete thioredoxin reduction	OBSOLETE. The chemical reactions and pathways resulting in the reduction of thioredoxin, a small disulfide-containing redox protein that serves as a general protein disulfide oxidoreductase.	tmpzr1t_l9r_go_relaxed.owl	thioredoxin synthesis|thioredoxin formation|thioredoxin anabolism|thioredoxin biosynthesis	https://github.com/geneontology/go-ontology/issues/20250				This term was obsoleted because it represents a molecular function.					True			biological_process											owl:Class	
GO:1902586	biolink:NamedThing	obsolete multi-organism intercellular transport	OBSOLETE. An intercellular transport which involves another organism.	tmpzr1t_l9r_go_relaxed.owl	multi organism intercellular transport	https://github.com/geneontology/go-ontology/issues/21459				This term was obsoleted because there is no evidence that this process exists.		jl	2013-12-19T13:25:05Z		True			biological_process											owl:Class	
GO:0005108	biolink:NamedThing	obsolete transmembrane ephrin	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	transmembrane ephrin					This term was made obsolete because it refers to a class of gene products.	GO:0046875|GO:0005887				True			molecular_function											owl:Class	
GO:0045093	biolink:NamedThing	obsolete interleukin-18 alpha subunit binding	OBSOLETE. Binding to alpha subunit of interleukin-18. IL-18a is a component of IL-18 that is essential for IL-18 binding on the surface of T-helper 1 cells.	tmpzr1t_l9r_go_relaxed.owl	IL-18Ra binding					This term was obsoleted because interleukin-18 is a single polypeptide and has no subunits					True			molecular_function											owl:Class	
GO:2001217	biolink:NamedThing	obsolete regulation of S/G2 transition of mitotic cell cycle	OBSOLETE. Any process that modulates the frequency, rate or extent of S/G2 transition of mitotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl	regulation of S/G2 transition of mitotic cell cycle					This term was made obsolete because it does not refer to a real biological process.	GO:0044770	dph	2011-11-16T09:14:42Z		True			biological_process											owl:Class	
GO:1990951	biolink:NamedThing	obsolete manchette assembly	OBSOLETE. The assembly and organization of the manchette, a tubular array of microtubules, possibly also containing actin filaments, that extends from the perinuclear ring surrounding the spermatid nucleus to the flagellar axoneme.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted at the TermGenie Gatekeeper stage.		krc	2016-05-11T00:05:35Z		True			biological_process											owl:Class	
GO:1900416	biolink:NamedThing	obsolete regulation of 4,6-pyruvylated galactose residue biosynthetic process by regulation of transcription from RNA polymerase II promoter	OBSOLETE. A regulation of transcription from RNA polymerase II promoter that results in regulation of 4,6-pyruvylated galactose residue biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it represents a GO-CAM model.		mah	2012-04-20T03:42:41Z		True			biological_process											owl:Class	
GO:0007345	biolink:NamedThing	obsolete embryogenesis and morphogenesis	OBSOLETE. Formation and development of an embryo and its organized structures.	tmpzr1t_l9r_go_relaxed.owl	embryogenesis and morphogenesis					This term was made obsolete because more appropriate terms were created. Morphogenesis in plants also occurs outside of embryogenesis.	GO:0009653|GO:0009790				True			biological_process											owl:Class	
GO:0005482	biolink:NamedThing	obsolete vesicle targeting	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	vesicle targeting					This term was made obsolete because it represents a biological process and not a molecular function.	GO:0016080|GO:0006903				True			molecular_function											owl:Class	
GO:0008159	biolink:NamedThing	obsolete positive transcription elongation factor activity	OBSOLETE. Any activity that increases the rate of transcription elongation, the addition of ribonucleotides to an RNA molecule following transcription initiation.	tmpzr1t_l9r_go_relaxed.owl	positive transcription elongation factor activity					This term was obsoleted because it is essentially identical to a Process term (specifically the Biological Process term which has been selected as a term to consider for reannotation), i.e. it is defined only in terms of the process it acts in and it does NOT convey any information about the molecular nature of the function or whether the function is based on binding DNA, on interacting with other proteins, or some other mechanism. To transfer all annotations without review, the BP term indicated is considered to be equivalent and thus the only appropriate destination for all annotations. To reannotate to a MF term, you will probably need to revisit the original literature or other primary data because this "MF" term was not defined in terms of mechanism of action and there are multiple possibilities in the revised MF structure. In reannotation, please also consider descendent terms of the suggested MF terms as a more specific term may be more appropriate than the MF terms indicated. Please be aware that you may wish to request a new term if the mechanism of action of this gene product is not yet represented or if you are annotating for an RNAP different than one for which there is a specific suggested term. Also note that if there is no information about how the gene product acts, it may be appropriate to annotate to the root term for molecular_function.	GO:0032786				True			molecular_function											owl:Class	
GO:0075067	biolink:NamedThing	obsolete growth or development of symbiont in host intercellular space	OBSOLETE. The increase in size or mass of symbiont, or the progression of the symbiont from an initial condition to a later condition, occurring in its host's intercellular space. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	growth or development of symbiont in host intercellular space					This term was made obsolete because it contained a conjunction (or).	GO:0051701|GO:0044114				True			biological_process											owl:Class	
GO:0031558	biolink:NamedThing	obsolete induction of apoptosis in response to chemical stimulus	OBSOLETE. Any process that directly activates any of the steps required for cell death by apoptosis as a result of a chemical stimulus.	tmpzr1t_l9r_go_relaxed.owl	induction of apoptosis in response to chemical stimulus|induction of apoptosis in response to chemical substance					This term was made obsolete because it is now superseded by better defined and more specific terms under the node of GO:0006915 apoptotic process.					True			biological_process											owl:Class	
GO:0005557	biolink:NamedThing	obsolete lymphocyte antigen	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	lymphocyte antigen					This term was made obsolete because it represents a gene product, and because describing something as an 'antigen' means that an organism can produce antibodies to it, which says nothing about the gene product activity.					True			molecular_function											owl:Class	
GO:0000364	biolink:NamedThing	obsolete second U2-type spliceosomal transesterification activity	OBSOLETE. Catalysis of the second transesterification reaction of U2-type spliceosomal mRNA splicing. Ligation of the two exons occurs via a transesterification reaction where the free 3'-hydroxyl group of the 5' exon is the nucleophile attacking the 3' splice site. Non-expressed sequences are now detached from the exons. In cis splicing, the intron is in a lariat structure. The catalytic site is thought to be formed by U6 and/or U2 snRNAs and/or associated proteins.	tmpzr1t_l9r_go_relaxed.owl	3'-splice site cleavage, exon ligation|second U2-type spliceosomal transesterification activity			GO:0000386		This term was made obsolete because the activities used in the U2- and U12-type complexes are the same. The cellular component ontology should (and does) represent the two different complexes, but the molecular function ontology should not.					True			molecular_function											owl:Class	
GO:0052359	biolink:NamedThing	obsolete catabolism by organism of glucan in other organism involved in symbiotic interaction	OBSOLETE. The chemical reactions and pathways performed by an organism resulting in the breakdown of glucan molecules within a second organism, where the two organisms are in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	catabolism by organism of glucan in other organism during symbiotic interaction	https://github.com/geneontology/go-ontology/issues/21396				This term was obsoleted because it represents an unnecessary grouping class.					True			biological_process											owl:Class	
GO:0006717	biolink:NamedThing	obsolete juvenile hormone binding	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	juvenile hormone binding					This term was made obsolete because it represents a molecular function and not a biological process.	GO:0005500				True			biological_process											owl:Class	
GO:1990924	biolink:NamedThing	obsolete amphisome membrane	OBSOLETE. The lipid bilayer surrounding the amphisome and separating its contents from the cell cytoplasm.	tmpzr1t_l9r_go_relaxed.owl	amphisomal membrane					This term was obsoleted at the TermGenie Gatekeeper stage.		bhm	2016-01-27T13:58:16Z		True			cellular_component											owl:Class	
GO:0033570	biolink:NamedThing	obsolete transferrin transmembrane transporter activity	OBSOLETE. Enables the transfer of transferrin from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/17157				This term was obsoleted because there is no evidence that this function exists.					True			molecular_function											owl:Class	
GO:0035827	biolink:NamedThing	obsolete rubidium ion transmembrane transporter activity	OBSOLETE. Enables the transfer of rubidium ions (Rb+) from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	Rb+ transmembrane transporter activity|rubidium transmembrane transporter activity|rubidium cation transmembrane transporter activity					This term has been obsoleted because it represents an assay, and not a physiological process.		bf	2011-05-04T02:55:30Z		True			molecular_function											owl:Class	
GO:0060859	biolink:NamedThing	obsolete regulation of vesicle-mediated transport involved in floral organ abscission	OBSOLETE. Any process that modulates the rate, frequency, or extent of the directed movement of substances within a cell by a cellular process that begins with the formation of membrane-bounded vesicles in which the transported substances are enclosed or located in the vesicle membrane which are then targeted to, and fuse with, an acceptor membrane contributing to the shedding of a floral organ.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/18200				This term was obsoleted because it does not represent a specific pathway.		dph	2009-08-12T03:56:21Z		True			biological_process											owl:Class	
GO:0046615	biolink:NamedThing	obsolete re-entry into mitotic cell cycle after pheromone arrest (sensu Saccharomyces)	OBSOLETE. The resumption of the Saccharomyces mitotic cell division cycle by pheromone-arrested cells that have not mated.	tmpzr1t_l9r_go_relaxed.owl	re-entry into mitotic cell cycle after pheromone arrest (sensu Saccharomyces)			GO:0000321		This term was made obsolete because there is no evidence that this process is unique to Saccharomyces.					True			biological_process											owl:Class	
GO:0015060	biolink:NamedThing	obsolete green-sensitive opsin	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	green-sensitive opsin					This term was made obsolete because it refers to a class of proteins.	GO:0007603|GO:0016021|GO:0009881|GO:0016918|GO:0046876				True			molecular_function											owl:Class	
GO:0006327	biolink:NamedThing	obsolete random coil binding	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	random coil binding					This term was made obsolete because it represents a molecular function and not a biological process.					True			biological_process											owl:Class	
GO:0100003	biolink:NamedThing	obsolete positive regulation of sodium ion transport by transcription from RNA polymerase II promoter	OBSOLETE. Any transcription from RNA polymerase II promoter process that positively regulates sodium ion transport.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it represents a GO-CAM model.		cjm	2015-04-02T04:13:19Z		True			biological_process											owl:Class	
GO:0106189	biolink:NamedThing	obsolete translocase activity acting on hydrons linked to the hydrolysis of a diphosphate	OBSOLETE. Catalysis of the translocation of hydrons linked to the hydrolysis of a diphosphate.	tmpzr1t_l9r_go_relaxed.owl					EC:7.1.3.-	This term was made obsolete because the concept of using the non-4 digit EC classes as parent terms for the transporter banch of the onotolgy was consided confusing.		hjd	2019-05-07T18:12:33Z		True			molecular_function											owl:Class	
GO:0003731	biolink:NamedThing	obsolete mRNA cap binding	OBSOLETE. Interacting selectively with the 7-methylguanosine cap at the 5' end of a nascent messenger RNA transcript.	tmpzr1t_l9r_go_relaxed.owl	mRNA cap binding					This term was made obsolete because the functional distinction for cap binding is the structure of the cap, not the type of RNA it is attached to.	GO:0000339				True			molecular_function											owl:Class	
GO:0039550	biolink:NamedThing	obsolete suppression by virus of host IRF3 activity by inhibition of DNA binding	OBSOLETE. Any process in which a virus stops, prevents, or reduces IRF3-dependent gene transcription, by preventing or reducing IRF3 binding to promoter sites.	tmpzr1t_l9r_go_relaxed.owl	inhibition by virus of host IRF3-DNA binding					The reason for obsoleting this term is that it is too specific. The exact molecular roles of the individual proteins should be captured separately.		bf	2012-01-19T04:27:25Z		True			biological_process											owl:Class	
GO:0044031	biolink:NamedThing	obsolete modification by symbiont of host protein by phosphorylation	OBSOLETE. The process in which an organism adds a phosphate group to a protein of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/21469				This term was obsoleted because it represents a molecular function.					True			biological_process											owl:Class	
GO:1905500	biolink:NamedThing	obsolete heteroreceptor complex assembly	OBSOLETE. The aggregation, arrangement and bonding together of a set of components to form a heteroreceptor complex.	tmpzr1t_l9r_go_relaxed.owl	heteroreceptor complex formation					This term was obsoleted at the TermGenie Gatekeeper stage.		pad	2016-09-27T10:49:56Z		True			biological_process											owl:Class	
GO:0019895	biolink:NamedThing	obsolete kinesin-associated mitochondrial adaptor activity	OBSOLETE. The activity of linking kinesins, cytoplasmic proteins responsible for moving vesicles and organelles towards the distal end of microtubules, to mitochondria.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/17668				This term was obsoleted because it represents the function of a specific protein.					True			molecular_function											owl:Class	
GO:0023004	biolink:NamedThing	obsolete activation of dopamine receptor signaling pathway	OBSOLETE. Any process that initiates the dopamine receptor protein signaling pathway through stimulation of the dopamine receptor.	tmpzr1t_l9r_go_relaxed.owl	stimulation of dopamine receptor signaling pathway|initiation of dopamine receptor signaling pathway|activation of dopamine receptor signaling pathway|activation of dopamine receptor signalling pathway					This term was made obsolete because the meaning of the term is ambiguous.	GO:0060161		2010-02-16T09:30:50Z		True			biological_process											owl:Class	
GO:1990866	biolink:NamedThing	obsolete response to sustained hypoxia	OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sustained stimulus indicating lowered oxygen tension.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted at the TermGenie Gatekeeper stage.		sl	2015-09-25T15:18:11Z		True			biological_process											owl:Class	
GO:0016962	biolink:NamedThing	obsolete receptor-associated protein activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	receptor-associated protein activity					This term was made obsolete because it describes a gene product and not a molecular function.	GO:0005102|GO:0005515				True			molecular_function											owl:Class	
GO:0039542	biolink:NamedThing	obsolete suppression by virus of host RIG-I K63-linked ubiquitination	OBSOLETE. Any process in which a virus stops, prevents, or reduces the rate or extent of K63-linked ubiquitination of RIG-I (also known as DDX58), thereby suppressing RIG-I signal transduction. Lys63-linked ubiquitination of the N-terminal CARD domains of RIG-I is crucial for the cytosolic RIG-I signaling pathway to elicit host antiviral innate immunity.	tmpzr1t_l9r_go_relaxed.owl	inhibition by virus of TRIM25-mediated ubiquitination of host RIG-I|inhibition by virus of host DDX58 K63-linked ubiquitination|inhibition by virus of host RIG-I activity by inhibition of RIG-I ubiquitination					The reason for obsoleting this term is that it is too specific. The exact molecular roles of the individual proteins should be captured separately.		bf	2012-01-18T02:30:29Z		True			biological_process											owl:Class	
GO:0009075	biolink:NamedThing	obsolete histidine family amino acid metabolic process	OBSOLETE. The chemical reactions and pathways involving amino acids of the histidine family.	tmpzr1t_l9r_go_relaxed.owl	histidine family amino acid metabolism|histidine family amino acid metabolic process			GO:0006547		This term was made obsolete because it was an unnecessary grouping term, as histidine would be the only member of this family.					True			biological_process											owl:Class	
GO:1900062	biolink:NamedThing	obsolete regulation of replicative cell aging	OBSOLETE. Any process that modulates the frequency, rate or extent of replicative cell aging.	tmpzr1t_l9r_go_relaxed.owl	regulation of replicative cell ageing	https://github.com/geneontology/go-ontology/issues/20007				This term was obsoleted because it represents an assay, not a true biological process.		dph	2012-01-26T01:46:47Z		True			biological_process											owl:Class	
GO:0039555	biolink:NamedThing	obsolete suppression by virus of host MDA-5 activity via MDA-5 binding	OBSOLETE. Any process in which a virus stops, prevents, or reduces the activity of MDA-5 (also known as IFIH1) by binding to MDA-5 itself. For example, direct binding of viral proteins to the host MDA-5 protein can inhibit interaction of MDA-5 with MAVS, its downstream signaling effector.	tmpzr1t_l9r_go_relaxed.owl	suppression by virus of host MDA5 activity by MDA-5 binding					The reason for obsoleting this term is that it is too specific. The exact molecular roles of the individual proteins should be captured separately.		bf	2012-03-09T04:06:46Z		True			biological_process											owl:Class	
GO:0016305	biolink:NamedThing	obsolete phosphatidylinositol 3-kinase activity, class II	OBSOLETE. A phosphoinositide 3-kinase which can phosphorylate phosphatidylinositol and phosphatidylinositol-4-phosphate; the human form can phosphorylate phosphatidylinositol-4,5-bisphosphate in the presence of phosphatidylserine.	tmpzr1t_l9r_go_relaxed.owl	phosphatidylinositol 3-kinase activity, class II|PI3KC2					This term was made obsolete because it represents a class of gene products.	GO:0046934|GO:0016303|GO:0035005				True			molecular_function											owl:Class	
GO:0017082	biolink:NamedThing	obsolete mineralocorticoid receptor activity	OBSOLETE. Combining with a mineralocorticoid and transmitting the signal to the transcriptional machinery by binding to a specific DNA sequence in order to modulate transcription by RNA polymerase II.	tmpzr1t_l9r_go_relaxed.owl	aldosterone receptor	https://github.com/geneontology/go-ontology/issues/16732									True			molecular_function											owl:Class	
GO:0016172	biolink:NamedThing	obsolete antifreeze activity	OBSOLETE. Inhibits the formation of ice crystals in organismal fluid (e.g. blood) at below freezing exogenous temperatures.	tmpzr1t_l9r_go_relaxed.owl	antifreeze activity					This term was made obsolete because it refers to a biological process.	GO:0050825|GO:0042309|GO:0050826				True			molecular_function											owl:Class	
GO:0140276	biolink:NamedThing	obsolete pericentric heterochromatin maintenance	OBSOLETE. Any heterochromatin maintenance that is involved in chromatin silencing at or near a centromere.	tmpzr1t_l9r_go_relaxed.owl	heterochromatin maintenance involved in chromatin silencing at pericentric region|heterochromatin maintenance involved in chromatin silencing at centromeric outer repeats|heterochromatin maintenance involved in chromatin silencing at centromere outer repeat region	https://github.com/geneontology/go-ontology/issues/19301				This term was obsoleted because it represents a phenotype.		bf	2013-08-21T10:13:39Z		True	GO:1902368		biological_process											owl:Class	
GO:0000180	biolink:NamedThing	obsolete cytosolic large ribosomal subunit	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	cytosolic large ribosomal subunit					This term was made obsolete because more specific children exist.	GO:0022625				True			cellular_component											owl:Class	
GO:0015256	biolink:NamedThing	obsolete monocarboxylate channel activity	OBSOLETE. This term was not defined before being made obsolete.	tmpzr1t_l9r_go_relaxed.owl	monocarboxylate channel activity					This term was made obsolete because this solute is transported by an active transporter rather than a channel.					True			molecular_function											owl:Class	
GO:0035121	biolink:NamedThing	obsolete tail morphogenesis	OBSOLETE. The process in which the anatomical structures of the tail are generated and organized. The tail is the hindmost part of some animals.	tmpzr1t_l9r_go_relaxed.owl	tail morphogenesis					This term was made obsolete because 'tail' has different meanings in different organisms, and is therefore not a useful grouping term.	GO:0048809|GO:0036342|GO:0003002				True			biological_process											owl:Class	
GO:0003734	biolink:NamedThing	obsolete small nuclear ribonucleoprotein	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	small nuclear ribonucleoprotein|snRNP			GO:0030532		This term was made obsolete because it describes a cellular component rather than a molecular function.					True			molecular_function											owl:Class	
GO:0061338	biolink:NamedThing	obsolete atrioventricular node impulse conduction delay	OBSOLETE. A heart process that modulates the propagation of the signal that causes the heart muscle to contract.	tmpzr1t_l9r_go_relaxed.owl	atrioventricular node impulse conduction delay					This term was made obsolete because it was created before the cardiac conduction overhaul, and represents a measurement rather than a process.	GO:0086016	dph	2010-09-29T08:55:53Z		True			biological_process											owl:Class	
GO:0008981	biolink:NamedThing	obsolete protease IV activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	protease IV activity			GO:0004252		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0106190	biolink:NamedThing	obsolete translocase activity acting on hydrons linked to a decarboxylation reaction	OBSOLETE. Catalysis of the translocation of hydrons linked to a decarboxylation reaction.	tmpzr1t_l9r_go_relaxed.owl					EC:7.1.4.-	This term was made obsolete because the concept of using the non-4 digit EC classes as parent terms for the transporter banch of the onotolgy was consided confusing.		hjd	2019-05-07T18:17:17Z		True			molecular_function											owl:Class	
GO:0052452	biolink:NamedThing	obsolete modulation by organism of symbiont innate immunity	OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of the innate immune response of the symbiont organism; the innate immune response is the symbiont's first line of defense against infection. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	modulation of symbiont innate immune response|modulation by organism of symbiont innate immunity					This term was made obsolete because it does not represent a real biological process.					True			biological_process											owl:Class	
GO:0052384	biolink:NamedThing	obsolete evasion or tolerance by organism of symbiont-produced reactive oxygen species	OBSOLETE. The process by which an organism avoids the effects of reactive oxygen species produced as a defense response by the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	evasion or tolerance of symbiont-produced ROS|evasion or tolerance of symbiont-produced active oxygen species|evasion or tolerance of reactive oxygen species produced by symbiont in response to organism|evasion by organism of cellular damage caused by symbiont oxidative burst|evasion or tolerance of defense-related symbiont oxidative burst|evasion or tolerance of defense-related symbiont metabolic burst|evasion or tolerance of symbiont-produced AOS|evasion or tolerance of symbiont-produced ROIs|evasion or tolerance of symbiont-produced reactive oxygen intermediates|evasion or tolerance by organism of symbiont-produced reactive oxygen species|evasion or tolerance of defense-related symbiont respiratory burst|evasion or tolerance by organism of reactive oxygen species produced during symbiont defense response					This term was made obsolete because it does not represent a real biological process.					True			biological_process											owl:Class	
GO:0030456	biolink:NamedThing	obsolete activation of MAPK (mating sensu Fungi)	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	activation of MAPK (mating sensu Fungi)			GO:0000750		This term was made obsolete because it is a gene product specific term.					True			biological_process											owl:Class	
GO:0046270	biolink:NamedThing	obsolete 4-toluenecarboxylate biosynthetic process	OBSOLETE. The chemical reactions and pathways resulting in the formation of 4-toluenecarboxylate, 4-methylbenzenecarboxylate, the anion of carboxylic acid attached to a methylbenzene molecule.	tmpzr1t_l9r_go_relaxed.owl	4-toluenecarboxylate synthesis|4-toluenecarboxylate biosynthesis|4-toluenecarboxylate anabolism|4-toluenecarboxylate formation|4-toluenecarboxylate biosynthetic process			GO:0019611		This term was made obsolete because 4-toluenecarboxylate is not synthesized by living organisms and GO does not cover non-biological processes.					True			biological_process											owl:Class	
GO:0061487	biolink:NamedThing	obsolete DNA replication initiation from late origin	OBSOLETE. The process in which DNA-dependent DNA replication is started at a late origin of replication. A late origin of replication refers to an origin that is activated late in S phase.	tmpzr1t_l9r_go_relaxed.owl	late replication origin firing					The reason for obsoletion is that there is no evidence that this is a different process from its parent term (DNA replication initiation, GO:0006270), but only that regulation of initiation at late origins differs from regulation of initiation at early origins.	GO:0101017	dph	2012-12-06T11:21:48Z		True			biological_process											owl:Class	
GO:0015032	biolink:NamedThing	obsolete storage protein import into fat body	OBSOLETE. The incorporation of hemolymph proteins by cells of the fat body of holometabolous insects, during the final larval stage. Uptake of these proteins prepares the insect for pupation and metamorphosis, since insect pupae do not feed and therefore depend on material that has been accumulated during larval life.	tmpzr1t_l9r_go_relaxed.owl	storage protein import into fat body cells|fat body metabolism|fat body metabolic process|storage protein transport into fat body cells|storage protein import by fat body cells|storage protein uptake into fat body cells|import of storage protein into fat body|fat body storage protein uptake	https://github.com/geneontology/go-ontology/issues/12935				The reason for obsoletion is that the data from the paper for which the term was requested can be accurately described using 'receptor-mediated endocytosis'.					True			biological_process											owl:Class	
GO:0003772	biolink:NamedThing	obsolete co-chaperonin activity	OBSOLETE. Co-chaperonins are proteins that bind to chaperones and this complex then folds misfolded proteins. Co-chaperonins by themselves do not possess chaperone activity.	tmpzr1t_l9r_go_relaxed.owl	co-chaperonin activity					This term was made obsolete because it represents a class of gene products rather than a molecular function.	GO:0006457|GO:0044183|GO:0051087				True			molecular_function											owl:Class	
GO:0038079	biolink:NamedThing	obsolete MAP kinase activity involved in osmosensory signaling pathway	OBSOLETE. Catalysis of the reaction: protein + ATP = protein phosphate + ADP by a mitogen-activated protein kinase, as part of a MAPK signaling cascade that passes on a signal within an osmosensory signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	MAPK activity involved in osmosensory signaling pathway|MAP kinase activity involved in osmosensory signalling pathway					This term has been obsoleted because it represents a GO-CAM model rather than a single GO term.		bf	2012-01-26T02:41:31Z		True			molecular_function											owl:Class	
GO:0030443	biolink:NamedThing	obsolete nuclear translocation of MAPK during sporulation (sensu Fungi)	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	nuclear translocation of MAPK during sporulation (sensu Fungi)					This term was made obsolete because it is a gene product specific term.					True			biological_process											owl:Class	
GO:0051848	biolink:NamedThing	obsolete active evasion of symbiont immune response via regulation of symbiont cytokine network	OBSOLETE. Any mechanism of active immune avoidance which works by regulating symbiont cytokine networks, e.g. by secreting proteins that mimic cytokine receptors that act to sequester symbiont cytokines and inhibit action. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	active evasion of symbiont immune response via regulation of symbiont cytokine network|active immune evasion via regulation of symbiont cytokine network|active immune evasion via modulation of symbiont cytokine network					This term was made obsolete because it does not represent a real process that exists in nature.					True			biological_process											owl:Class	
GO:0052431	biolink:NamedThing	obsolete modulation by organism of symbiont T-cell mediated immune response	OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of the T-cell mediated immune response of a symbiont organism, where the two organisms are in a symbiotic interaction. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	modulation by organism of symbiont T-cell mediated immune response					This term was made obsolete because it does not represent a real biological process.					True			biological_process											owl:Class	
GO:0008769	biolink:NamedThing	obsolete X-His dipeptidase activity	OBSOLETE. Catalysis of the hydrolysis of Xaa-His dipeptides.	tmpzr1t_l9r_go_relaxed.owl	aminoacylhistidine dipeptidase activity|dipeptidase M|aminoacyl-histidine dipeptidase activity|carnosinase activity|X-His dipeptidase activity|Xaa-His dipeptidase activity|homocarnosinase activity				MetaCyc:3.4.13.3-RXN|EC:3.4.13.3	This term was made obsolete because it represents a gene product.	GO:0008235|GO:0016805				True			molecular_function											owl:Class	
GO:0033187	biolink:NamedThing	obsolete inositol hexakisphosphate 4-kinase or 6-kinase activity	OBSOLETE. Catalysis of the reaction: ATP + 1D-myo-inositol hexakisphosphate = ADP + 4-diphospho-1D-myo-inositol (1,2,3,5,6)pentakisphosphate, and ATP + 1D-myo-inositol hexakisphosphate = ADP + 6-diphospho-1D-myo-inositol (1,2,3,4,5)pentakisphosphate.	tmpzr1t_l9r_go_relaxed.owl	inositol hexakisphosphate 4-kinase or 6-kinase activity					This term was made obsolete because it represents two reactions, and should be two separate terms.	GO:0000831|GO:0000830				True			molecular_function											owl:Class	
GO:0019204	biolink:NamedThing	obsolete nucleotide phosphatase activity	OBSOLETE. Catalysis of the reaction: phosphopolynucleotide + H2O = polynucleotide + phosphate.	tmpzr1t_l9r_go_relaxed.owl	nucleotide phosphatase activity					This term was defined to cover phosphatase activity against polynucleotides, but had subclasses and annotations for phosphatase activity against free nucleotides.  It has therefore been split. Use GO:0098519 (nucleotide phosphatase activity, acting against free nucleotides) or GO:0098518 (polynucleotide phosphatase activity).	GO:0098519|GO:0098518				True			molecular_function											owl:Class	
GO:0042394	biolink:NamedThing	obsolete ecdysis, protein-based cuticle	OBSOLETE. The shedding of the old protein-based cuticular fragments during the molting cycle. Examples of this process are found in invertebrates.	tmpzr1t_l9r_go_relaxed.owl	ecdysis, protein-based cuticle					This term was made obsolete because 'protein-based cuticle' is an unnecessary grouping term.	GO:0018990|GO:0042395				True			biological_process											owl:Class	
GO:0014917	biolink:NamedThing	obsolete positive regulation of diuresis by pressure natriuresis	OBSOLETE. The process in which pressure natriuresis increases the rate of diuresis.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of diuresis by pressure natriuresis			GO:0035818		This term was made obsolete because its definition was inaccurate.					True			biological_process											owl:Class	
GO:0005571	biolink:NamedThing	obsolete untranslated RNA	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	untranslated RNA					Note that this term was deleted from GO and was restored to the ontology in Feb 2003 to ensure that the ID is not reused.					True			cellular_component											owl:Class	
GO:0008978	biolink:NamedThing	obsolete prepilin peptidase activity	OBSOLETE. Catalysis of the cleavage of a Gly-Phe bond to release an N-terminal, basic peptide of 5-8 residues from type IV prepilin, and then N-methylates the new N-terminal amino group, the methyl donor being S-adenosyl-L-methionine.	tmpzr1t_l9r_go_relaxed.owl	prepilin peptidase activity			GO:0004190		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:1990366	biolink:NamedThing	obsolete response to organic acid	OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic acid.	tmpzr1t_l9r_go_relaxed.owl	response to organic acid					This term was obsoleted at the TermGenie Gatekeeper stage.		tt	2014-04-23T22:21:26Z		True			biological_process											owl:Class	
GO:0016184	biolink:NamedThing	obsolete synaptic vesicle retrieval	OBSOLETE. Return of a vesicle from the postsynaptic membrane to presynaptic membrane.	tmpzr1t_l9r_go_relaxed.owl	synaptic vesicle retrieval					This term was made obsolete because it was wrongly defined.	GO:0016192				True			biological_process											owl:Class	
GO:0010505	biolink:NamedThing	obsolete positive regulation of cell cycle arrest in response to nitrogen starvation	OBSOLETE. Any process that increases the frequency or rate of cell cycle arrest in response to nitrogen starvation.	tmpzr1t_l9r_go_relaxed.owl						This term was made obsolete because it is superfluous, as only the more specific 'mitotic G1 cell cycle arrest in response to nitrogen starvation' has been observed.					True			biological_process											owl:Class	
GO:0001619	biolink:NamedThing	obsolete lysosphingolipid and lysophosphatidic acid receptor activity	OBSOLETE. Combining with lysosphingolipid or lysophosphatidic acid to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	lysosphingolipid and lysophosphatidic acid receptor activity						GO:0070915|GO:0038036				True			molecular_function											owl:Class	
GO:0036206	biolink:NamedThing	obsolete regulation of histone gene expression	OBSOLETE. Any process that modulates the frequency, rate or extent of expression of a histone-encoding gene. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein.	tmpzr1t_l9r_go_relaxed.owl	regulation of expression of histone-encoding gene					This term was obsoleted because it referes to a specific gene product. The gene product should be captured as an annotation extension using 'has input'.	GO:0006357	bf	2012-04-24T05:01:28Z		True			biological_process											owl:Class	
GO:0010194	biolink:NamedThing	obsolete microRNA metabolic process	OBSOLETE. The chemical reactions and pathways involving microRNA, a large family of 21-22 nucleotide non-coding RNAs with presumed post-transcriptional regulatory activity.	tmpzr1t_l9r_go_relaxed.owl	microRNA metabolic process			GO:0035196		This term was made obsolete because it implies further processing of an end product rather than its production.					True			biological_process											owl:Class	
GO:0005568	biolink:NamedThing	obsolete mitochondrial rRNA	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	mitochondrial rRNA					Note that this term was deleted from GO rather than being made obsolete and was restored to the ontology in Feb 2003 to ensure that the ID is not reused.					True			cellular_component											owl:Class	
GO:0009497	biolink:NamedThing	obsolete 3Fe-4S/4Fe-4S electron transfer carrier	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	3Fe-4S/4Fe-4S electron transfer carrier			GO:0009055		This term was made obsolete because it refers to a class of gene products.					True			molecular_function											owl:Class	
GO:0005508	biolink:NamedThing	obsolete copper/cadmium binding	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	copper/cadmium binding					This term was made obsolete because it represents a composite function.	GO:0005507|GO:0046870				True			molecular_function											owl:Class	
GO:0008167	biolink:NamedThing	obsolete sigma virus replication	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	sigma virus replication			GO:0019079							True			biological_process											owl:Class	
GO:1902880	biolink:NamedThing	obsolete positive regulation of BMP signaling pathway involved in spinal cord association neuron specification	OBSOLETE. Any process that activates or increases the frequency, rate or extent of BMP signaling pathway involved in spinal cord association neuron specification.	tmpzr1t_l9r_go_relaxed.owl	upregulation of BMP signaling pathway involved in spinal cord association neuron specification|up-regulation of BMP signaling pathway involved in spinal cord association neuron specification|up-regulation of BMP signalling pathway involved in spinal cord association neuron specification|up-regulation of bone morphogenetic protein signaling pathway involved in spinal cord association neuron specification|up-regulation of bone morphogenetic protein signalling pathway involved in spinal cord association neuron specification|upregulation of bone morphogenetic protein signaling pathway involved in spinal cord association neuron specification|positive regulation of bone morphogenetic protein signalling pathway involved in spinal cord association neuron specification|activation of bone morphogenetic protein signaling pathway involved in spinal cord association neuron specification|upregulation of bone morphogenetic protein signalling pathway involved in spinal cord association neuron specification|activation of BMP signalling pathway involved in spinal cord association neuron specification|positive regulation of BMP signalling pathway involved in spinal cord association neuron specification|activation of BMP signaling pathway involved in spinal cord association neuron specification|up regulation of BMP signaling pathway involved in spinal cord association neuron specification|activation of bone morphogenetic protein signalling pathway involved in spinal cord association neuron specification|up regulation of BMP signalling pathway involved in spinal cord association neuron specification|positive regulation of bone morphogenetic protein signaling pathway involved in spinal cord association neuron specification|up regulation of bone morphogenetic protein signalling pathway involved in spinal cord association neuron specification|up regulation of bone morphogenetic protein signaling pathway involved in spinal cord association neuron specification|upregulation of BMP signalling pathway involved in spinal cord association neuron specification					The reason for obsoletion is that this term represents a GO-CAM model.		mr	2014-04-03T15:25:43Z		True			biological_process											owl:Class	
GO:2000686	biolink:NamedThing	obsolete regulation of rubidium ion transmembrane transporter activity	OBSOLETE. Any process that modulates the frequency, rate or extent of rubidium ion transmembrane transporter activity.	tmpzr1t_l9r_go_relaxed.owl	regulation of rubidium cation transmembrane transporter activity|regulation of Rb+ transmembrane transporter activity|regulation of rubidium transmembrane transporter activity					This term has been obsoleted because it represents an assay, and not a physiological process.		bf	2011-05-11T09:27:29Z		True			biological_process											owl:Class	
GO:0008077	biolink:NamedThing	obsolete Hsp70/Hsp90 organizing protein activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	Hsp70/Hsp90 organising protein activity|Hsp70/Hsp90 organizing protein activity					This term was made obsolete because it represents a specific gene product rather than a molecular function.	GO:0030674				True			molecular_function											owl:Class	
GO:0005574	biolink:NamedThing	obsolete DNA	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	DNA					Note that this term was deleted from GO and was restored to the ontology in Feb 2003 to ensure that the ID is not reused.					True			cellular_component											owl:Class	
GO:0001149	biolink:NamedThing	obsolete transcription factor activity, bacterial-type RNA polymerase termination site sequence-specific binding	OBSOLETE. Binding to a sequence of DNA that is a termination site for bacterial-type RNA polymerase in order to promote transcription termination by bacterial-type RNA polymerase.	tmpzr1t_l9r_go_relaxed.owl	bacterial-type RNA polymerase termination site sequence-specific DNA binding transcription factor activity	https://github.com/geneontology/go-ontology/issues/16730						krc	2011-01-27T03:08:41Z		True			molecular_function											owl:Class	
GO:0005061	biolink:NamedThing	obsolete aryl hydrocarbon receptor nuclear translocator activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	aryl hydrocarbon receptor nuclear translocator activity					This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
OIO:hasAlternativeId	biolink:NamedThing	has_alternative_id		tmpzr1t_l9r_go_relaxed.owl																									owl:AnnotationProperty	
GO:0072362	biolink:NamedThing	obsolete regulation of glycolytic process by negative regulation of transcription from RNA polymerase II promoter	OBSOLETE. Any process that modulates the frequency, rate or extent of glycolysis by stopping, preventing, or reducing the frequency, rate or extent of transcription from an RNA polymerase II promoter.	tmpzr1t_l9r_go_relaxed.owl	regulation of glycolysis by negative regulation of transcription from an RNA polymerase II promoter					The reason for obsoletion is that this term represented a GO-CAM model.		mah	2010-11-16T02:59:32Z		True			biological_process											owl:Class	
GO:0019881	biolink:NamedThing	obsolete streptomycin susceptibility/resistance	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	streptomycin susceptibility/resistance			GO:0046679		This term was made obsolete because 'susceptibility/resistance' implies a phenotype rather than a biological process.					True			biological_process											owl:Class	
GO:0001074	biolink:NamedThing	obsolete transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding involved in preinitiation complex assembly	OBSOLETE. Binding to a sequence of DNA that is in cis with and relatively close to a core promoter for RNA polymerase II (RNAP II) in order to promote assembly of the transcriptional preinitiation complex (PIC), the formation of which is a prerequisite for transcription from an RNA polymerase II promoter.	tmpzr1t_l9r_go_relaxed.owl	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in preinitiation complex assembly|transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding involved in preinitiation complex assembly	https://github.com/geneontology/go-ontology/issues/16554				This term has been obsoleted because it represents a GO-CAM model.		krc	2010-10-22T02:30:43Z		True			molecular_function											owl:Class	
GO:0019796	biolink:NamedThing	obsolete nonprotein amino acid catabolic process	OBSOLETE. The chemical reactions and pathways resulting in the breakdown of any amino acid not found, or rarely found, in peptide linkage in proteins.	tmpzr1t_l9r_go_relaxed.owl	nonprotein amino acid catabolism|nonprotein amino acid catabolic process|nonprotein amino acid degradation|nonprotein amino acid breakdown			GO:0009063		This term was made obsolete because it was a grouping term that was poorly defined and did not provide a particularly meaningful grouping, since even for those amino acids commonly found in proteins, not all molecules necessarily end up incorporated into proteins. The term also violated the principle of positivity.					True			biological_process											owl:Class	
GO:0140579	biolink:NamedThing	obsolete oxidoreductase activity, reducing metal ions	OBSOLETE. Catalysis of an oxidation-reduction in which the metal ion is reduced.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/20675				This term was obsoleted because it is an unnecessary grouping class.	GO:0016722	pg	2021-01-13T06:55:01Z		True			molecular_function											owl:Class	
GO:1905481	biolink:NamedThing	obsolete cytoplasmic sequestering of protein involved in mitotic DNA replication checkpoint	OBSOLETE. Any cytoplasmic sequestering of protein that is involved in mitotic DNA replication checkpoint.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it represents a GO-CAM model.		vw	2016-09-22T18:20:35Z		True			biological_process											owl:Class	
GO:0035109	biolink:NamedThing	obsolete imaginal disc-derived limb morphogenesis	OBSOLETE. The process in which the anatomical structures of limbs that are derived from an imaginal disc are generated and organized. A limb is an appendage of an animal used for locomotion or grasping. An example of this process is found in Drosophila melanogaster.	tmpzr1t_l9r_go_relaxed.owl	imaginal disc-derived limb morphogenesis					This term was made obsolete because the term 'limb' is not widely used in the insect community. In GO, 'limb' is used to describe the vertebrate hindlimbs and forelimbs.	GO:0035114				True			biological_process											owl:Class	
GO:0006280	biolink:NamedThing	obsolete mutagenesis	OBSOLETE. The process by which genetic material undergoes a detectable and heritable structural change. There are three categories of mutation: genome mutations, involving addition or subtraction of one or more whole chromosomes; chromosome mutations, which alter the structure of chromosomes; and gene mutations, where the structure of a gene is altered at the molecular level.	tmpzr1t_l9r_go_relaxed.owl	mutagenesis					This term was made obsolete because mutagenesis is not a valid biological process in which gene products would normally participate. Rather, mutations arise from DNA replication errors or damage by an extrinsic agent.	GO:0051276|GO:0006281				True			biological_process											owl:Class	
GO:0019032	biolink:NamedThing	obsolete viral glycoprotein	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	viral glycoprotein					This term was made obsolete because it represents a type of gene product and not a location or complex.	GO:0019031				True			cellular_component											owl:Class	
GO:1900417	biolink:NamedThing	obsolete negative regulation of transmembrane transport by negative regulation of transcription from RNA polymerase II promoter	OBSOLETE. A negative regulation of transcription from RNA polymerase II promoter that results in negative regulation of transmembrane transport.	tmpzr1t_l9r_go_relaxed.owl						The term was obsoleted because it is better represented by a GO-CAM model.		mah	2012-04-20T03:42:55Z		True			biological_process											owl:Class	
GO:0009406	biolink:NamedThing	obsolete virulence	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	virulence					This term was made obsolete because it represents a phenotype rather than a biological process.	GO:0090729|GO:0016032				True			biological_process											owl:Class	
GO:1990419	biolink:NamedThing	obsolete response to elemental metal	OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an elemental metal stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to elemental metal					This term was obsoleted at the TermGenie Gatekeeper stage.		sl	2014-07-15T20:17:56Z		True			biological_process											owl:Class	
GO:0016845	biolink:NamedThing	obsolete other carbon-nitrogen lyase activity	OBSOLETE. Catalysis of the cleavage of a carbon-nitrogen bond. Enzymes with this activity are 'miscellaneous' carbon-nitrogen lyases that cannot be grouped into one of the specific subclasses of the carbon-nitrogen lyases.	tmpzr1t_l9r_go_relaxed.owl	other carbon-nitrogen lyase activity					This term was made obsolete because it was an unnecessary grouping term.	GO:0016840				True			molecular_function											owl:Class	
GO:0007108	biolink:NamedThing	obsolete cytokinesis, initiation of separation	OBSOLETE. The process involved in starting cell separation.	tmpzr1t_l9r_go_relaxed.owl	initiation of separation involved in cytokinesis|cytokinesis, initiation of separation					This term was obsoleted because it was vaguely defined and had very likely been used in error. Consider the child terms of cytokinesis related to ring positioning, assembly, ring constriction etc. which would be more appropriate.					True			biological_process											owl:Class	
GO:0005514	biolink:NamedThing	obsolete calcium ion storage activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	calcium ion storage activity					This term was made obsolete because it represents a biological process.	GO:0005509|GO:0051208				True			molecular_function											owl:Class	
GO:0010703	biolink:NamedThing	obsolete negative regulation of histolysis	OBSOLETE. Any process that decreases the rate, frequency or extent of the breakdown of tissues; usually, if not always, accompanied by cell death.	tmpzr1t_l9r_go_relaxed.owl	inhibition of histolysis|down regulation of histolysis|down-regulation of histolysis|downregulation of histolysis					This term was made obsolete because it refers to a phenotype. When death of a cell or tissue is a result of a true biological process, this should be captured using 'programmed cell death' or one of its descendants.	GO:0008219|GO:0012501				True			biological_process											owl:Class	
GO:0035953	biolink:NamedThing	obsolete regulation of dipeptide transport by regulation of transcription from RNA polymerase II promoter	OBSOLETE. Any process that modulates the frequency, rate or extent of dipeptide transport, by regulation of transcription from an RNA polymerase II promoter.	tmpzr1t_l9r_go_relaxed.owl	regulation of dipeptide transport by regulation of transcription from Pol II promoter					This term was obsoleted because it represents a GO-CAM model.		bf			True			biological_process											owl:Class	
GO:0071849	biolink:NamedThing	obsolete G1 cell cycle arrest in response to nitrogen starvation	OBSOLETE. The process in which the cell cycle is halted during G1 phase, as a result of deprivation of nitrogen.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/20989				This term was obsoleted because it does not represent a specific process.		mah	2010-09-10T02:46:11Z		True			biological_process											owl:Class	
GO:0038080	biolink:NamedThing	obsolete MAP kinase kinase activity involved in osmosensory signaling pathway	OBSOLETE. Catalysis of the concomitant phosphorylation of threonine (T) and tyrosine (Y) residues in a Thr-Glu-Tyr (TEY) thiolester sequence in a MAP kinase (MAPK) substrate, as part of a MAPK signaling cascade that passes on a signal within an osmosensory signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	MAP kinase kinase activity involved in osmosensory signalling pathway|MAP2K activity involved in osmosensory signaling pathway|MAPKK activity involved in osmosensory signaling pathway					This term has been obsoleted because it represents a GO-CAM model rather than a single GO term.		bf	2012-01-26T02:41:31Z		True			molecular_function											owl:Class	
GO:0015323	biolink:NamedThing	obsolete type V protein secretor activity	OBSOLETE. This term was not defined before being made obsolete.	tmpzr1t_l9r_go_relaxed.owl	type V protein secretor activity					This term was made obsolete because it does not accurately reflect the function of the proteins involved.					True			molecular_function											owl:Class	
GO:0035559	biolink:NamedThing	obsolete MAPKKK cascade involved in epidermal growth factor receptor signaling	OBSOLETE. The process in which a signal is passed from the epidermal growth factor receptor (EGFR) to components of the MAPKKK cascade, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell.	tmpzr1t_l9r_go_relaxed.owl	MAPKKK cascade involved in signaling from the EGFR|MAPKKK cascade involved in epidermal growth factor receptor signalling|MAPKKK cascade involved in epidermal growth factor receptor signaling					This term was made obsolete because the syntax of the term is incorrect.	GO:0038029	bf	2010-05-14T01:53:15Z		True			biological_process											owl:Class	
GO:0052136	biolink:NamedThing	obsolete negative chemotaxis on or near host	OBSOLETE. The directed movement of a motile cell or organism towards a lower concentration of a specific chemical on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/18819				This term was obsoleted because it represents both a process and a location.					True			biological_process											owl:Class	
GO:0045715	biolink:NamedThing	obsolete negative regulation of low-density lipoprotein particle receptor biosynthetic process	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of low-density lipoprotein particle receptors.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of low-density lipoprotein receptor biosynthetic process|down-regulation of low-density lipoprotein receptor biosynthetic process|negative regulation of low-density lipoprotein receptor biosynthesis|negative regulation of low-density lipoprotein receptor anabolism|negative regulation of low-density lipoprotein receptor synthesis|downregulation of low-density lipoprotein receptor biosynthetic process|negative regulation of low-density lipoprotein receptor formation|inhibition of low-density lipoprotein receptor biosynthetic process|down regulation of low-density lipoprotein receptor biosynthetic process	https://github.com/geneontology/go-ontology/issues/19900				The reason for obsoletion is that those represent specific gene products, and genes annotated to those terms should be annotated to 'regulation of gene expression' or 'regulation of transcription' or some signaling term.					True			biological_process											owl:Class	
RO:0002404	biolink:NamedThing	causally downstream of		tmpzr1t_l9r_go_relaxed.owl					RO:0002404									external									causally_downstream_of			
GO:0045758	biolink:NamedThing	obsolete positive regulation of actin polymerization and/or depolymerization	OBSOLETE. Any process that activates or increases the frequency, rate or extent of actin polymerization and/or depolymerization.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of actin polymerization and/or depolymerization					This term was made obsolete because it has been split.	GO:0030836|GO:0030838				True			biological_process											owl:Class	
GO:0004928	biolink:NamedThing	obsolete frizzled receptor activity	OBSOLETE. Combining with a member of the Wnt-family of signaling molecules to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	frizzled receptor activity			GO:0042813		This term was made obsolete because it represents a gene product rather than an activity.	GO:0016055				True			molecular_function											owl:Class	
GO:1904500	biolink:NamedThing	obsolete negative regulation of chromatin-mediated maintenance of transcription	OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of chromatin-mediated maintenance of transcription.	tmpzr1t_l9r_go_relaxed.owl	inhibition of chromatin-mediated maintenance of transcription|down regulation of chromatin-mediated maintenance of transcription|downregulation of chromatin-mediated maintenance of transcription|down-regulation of chromatin-mediated maintenance of transcription					This term was obsoleted because it represents a readout.		nc	2015-07-24T09:31:14Z		True			biological_process											owl:Class	
GO:1990602	biolink:NamedThing	obsolete importin alpha-subunit nuclear import complex	OBSOLETE. A trimeric protein complex which functions to transport the importin alpha-subunit into the nucleus through the nuclear pore to facilitate another round of mRNP incorporation and regulation. In Drosophila it consists of Cdm (Imp13), Mago and Tsu (Y14).	tmpzr1t_l9r_go_relaxed.owl	Cdm-Mago-Tsu complex|Importin13-Mago-Tsu complex					The reason for obsoletion is that these terms include the substrate of the reaction.		bhm	2015-01-09T16:28:54Z		True			cellular_component											owl:Class	
GO:0004191	biolink:NamedThing	obsolete barrierpepsin activity	OBSOLETE. Catalysis of the selected cleavage of the Leu6-Lys7 bond in the pheromone alpha-mating factor.	tmpzr1t_l9r_go_relaxed.owl	barrierpepsin activity|barrier proteinase activity|Bar proteinase activity|extracellular 'barrier' protein activity			GO:0004190		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0000362	biolink:NamedThing	obsolete first U2-type spliceosomal transesterification activity	OBSOLETE. Catalysis of the first transesterification reaction of U2-type spliceosomal mRNA splicing. The intron branch site adenosine is the nucleophile attacking the 5' splice site, resulting in cleavage at this position. In cis splicing, this is the step that forms a lariat structure of the intron RNA, which is still joined to the 3' exon. The catalytic site is thought to be formed by U6 and/or U2 snRNA, and/or associated proteins.	tmpzr1t_l9r_go_relaxed.owl	first U2-type spliceosomal transesterification activity|lariat formation, 5'-splice site cleavage			GO:0000384		This term was made obsolete because the activities used in the U2- and U12-type complexes are the same. The cellular component ontology should (and does) represent the two different complexes, but the molecular function ontology should not.					True			molecular_function											owl:Class	
GO:0015642	biolink:NamedThing	obsolete bacteriolytic toxin activity	OBSOLETE. Acts as to cause lysis of bacterial cells.	tmpzr1t_l9r_go_relaxed.owl	bacteriolytic toxin activity					This term was made obsolete because it represents a class of gene products and not a molecular function.	GO:0019835				True			molecular_function											owl:Class	
GO:0140316	biolink:NamedThing	obsolete vesicular transport adaptor activity	OBSOLETE. Binding directly to sorting signals in the cytosolic tails of transmembrane cargos (or transmembrane cargo receptors serving as recognition interfaces for lumenal cargos), to concentrate them into vesicles or tubules for transport via intracellular vesicular transport or the secretory pathway.	tmpzr1t_l9r_go_relaxed.owl						Thi sterm was obsoleted because it represented an unnecessary grouping class.		pg	2019-03-28T12:03:57Z		True			molecular_function											owl:Class	
GO:0030005	biolink:NamedThing	obsolete cellular di-, tri-valent inorganic cation homeostasis	OBSOLETE. Any process involved in the maintenance of an internal steady state of divalent or trivalent cations at the level of a cell.	tmpzr1t_l9r_go_relaxed.owl	cellular di-, tri-valent inorganic cation homeostasis						GO:0072504|GO:0072503				True			biological_process											owl:Class	
GO:0010834	biolink:NamedThing	obsolete telomere maintenance via telomere shortening	OBSOLETE. Any process that contributes to the maintenance of proper telomeric length and structure by affecting and monitoring the activity of telomeric proteins and shortening the telomeric DNA.	tmpzr1t_l9r_go_relaxed.owl	telomere maintenance via telomere shortening					This term was made obsolete because it represents a phenotype.	GO:1903824				True			biological_process											owl:Class	
GO:0044789	biolink:NamedThing	obsolete modulation by host of viral release from host cell	OBSOLETE. A process in which a host organism modulates the frequency, rate or extent of the release of a virus with which it is infected, from its cells.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/22168		GO:0019076		This term was obsoleted because there is no evidence that it is a regulated process.		jl	2013-06-06T10:51:10Z		True			biological_process											owl:Class	
GO:1901350	biolink:NamedThing	obsolete cell-cell signaling involved in cell-cell junction organization	OBSOLETE. Any cell-cell signaling that is involved in cell-cell junction organization.	tmpzr1t_l9r_go_relaxed.owl	cell-cell signalling involved in cell-cell junction organization|cell-cell signalling involved in intercellular junction assembly and maintenance|cell-cell signalling involved in cell-cell junction biogenesis|cell-cell signaling involved in intercellular junction assembly and maintenance|cell-cell signaling involved in cell-cell junction organisation|cell-cell signaling involved in cell-cell junction biogenesis|cell-cell signalling involved in cell-cell junction assembly and maintenance|cell-cell signalling involved in cell-cell junction organisation|cell-cell signaling involved in cell-cell junction assembly and maintenance					The reasons for obsoletion are that: (1) the term was created in 2012 and it had been used for only 1 NAS annotation (UniProt) since then; and (2) it can be represented as a GO-CAM.		rph	2012-09-11T09:15:04Z		True			biological_process											owl:Class	
GO:0001318	biolink:NamedThing	obsolete formation of oxidatively modified proteins involved in replicative cell aging	OBSOLETE. Chemical reaction, between proteins and reactive oxygen species, that occurs in dividing cells as they age and leads to a variety of changes in the affected proteins, including increases in protein carbonyl content, oxidized methionine, protein hydrophobicity, and cross-linking.	tmpzr1t_l9r_go_relaxed.owl	formation of oxidatively modified proteins during replicative cell aging|formation of oxidatively modified proteins during replicative cell ageing	https://github.com/geneontology/go-ontology/issues/20007				This term was obsoleted because it represents an assay, not a true biological process.					True			biological_process											owl:Class	
GO:1900405	biolink:NamedThing	obsolete regulation of cell separation after cytokinesis by regulation of transcription from RNA polymerase II promoter	OBSOLETE. A regulation of transcription from RNA polymerase II promoter that results in regulation of  cell separation after cytokinesis.	tmpzr1t_l9r_go_relaxed.owl	regulation of cytokinetic cell separation by regulation of transcription from RNA polymerase II promoter							mah	2012-04-20T02:46:10Z		True			biological_process											owl:Class	
GO:0003930	biolink:NamedThing	obsolete RAS small monomeric GTPase activity	OBSOLETE. Catalysis of the reaction: GTP + H2O = GDP + phosphate.	tmpzr1t_l9r_go_relaxed.owl	RAS small monomeric GTPase activity			GO:0003924		This term was made obsolete because it represents a gene product.	GO:0001558				True			molecular_function											owl:Class	
GO:0010320	biolink:NamedThing	obsolete arginine/lysine endopeptidase activity	OBSOLETE. Catalysis of the hydrolysis of peptide linkages in oligopeptides or polypeptides by a reaction mechanism in which arginine or lysine residues act as nucleophiles.	tmpzr1t_l9r_go_relaxed.owl	arginine/lysine endopeptidase activity					This term was made obsolete because it was defined incorrectly: there are no known peptidases using a catalytic mechanism involving arginine and lysine, and the Arabidopsis metacaspases that prompted addition of this term are in fact cysteine-type endopeptidases.	GO:0004175|GO:0004197				True			molecular_function											owl:Class	
GO:0017170	biolink:NamedThing	obsolete KU70 binding	OBSOLETE. Binding to Ku70, a protein involved in non-homologous DNA end joining.	tmpzr1t_l9r_go_relaxed.owl	KU70 binding					This term was made obsolete because it represents binding to an individual protein.					True			molecular_function											owl:Class	
GO:0052352	biolink:NamedThing	obsolete biosynthesis by host of substance in symbiont	OBSOLETE. The chemical reactions and pathways performed by an organism in its symbiont resulting in the formation of substances. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/18787				This term was obsoleted because there is no evidence that this process exists.					True			biological_process											owl:Class	
GO:0005081	biolink:NamedThing	obsolete receptor signaling protein serine/threonine phosphatase signaling protein activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	receptor signalling protein serine/threonine phosphatase signalling protein activity|receptor signaling protein serine/threonine phosphatase signaling protein activity					This term was made obsolete because the meaning of the term is ambiguous and it incorporates process information.	GO:0035556				True			molecular_function											owl:Class	
GO:1904001	biolink:NamedThing	obsolete positive regulation of pyrimidine-containing compound salvage by positive regulation of transcription from RNA polymerase II promoter	OBSOLETE. A positive regulation of transcription from RNA polymerase II promoter that results in positive regulation of pyrimidine-containing compound salvage.	tmpzr1t_l9r_go_relaxed.owl	activation of pyrimidine salvage by positive regulation of transcription from RNA polymerase II promoter|up-regulation of pyrimidine-containing compound salvage by positive regulation of transcription from RNA polymerase II promoter|up regulation of pyrimidine salvage by positive regulation of transcription from RNA polymerase II promoter|upregulation of pyrimidine salvage by positive regulation of transcription from RNA polymerase II promoter|up-regulation of pyrimidine salvage by positive regulation of transcription from RNA polymerase II promoter|up regulation of pyrimidine-containing compound salvage by positive regulation of transcription from RNA polymerase II promoter|activation of pyrimidine-containing compound salvage by positive regulation of transcription from RNA polymerase II promoter|positive regulation of pyrimidine salvage by positive regulation of transcription from RNA polymerase II promoter|upregulation of pyrimidine-containing compound salvage by positive regulation of transcription from RNA polymerase II promoter					This term was obsoleted because it represents a GO-CAM model.		pr	2015-03-05T21:25:42Z		True			biological_process											owl:Class	
GO:0009412	biolink:NamedThing	obsolete response to heavy metal	OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heavy metal stimulus. Heavy metals are those metals that can form a coordination bond with a protein; this definition includes the following biologically relevant heavy metals: Cd, Co, Cu, Fe, Hg, Mn, Mo, Ni, V, W, Zn.	tmpzr1t_l9r_go_relaxed.owl	response to heavy metal					This term was made obsolete because 'heavy metal' is an ambiguous grouping term which has no set meaning (see Pure Appl. Chem. Vol. 74, No. 5, pp. 793-807, 2002, for more information).	GO:0010038				True			biological_process											owl:Class	
GO:0033392	biolink:NamedThing	obsolete actin homodimerization activity	OBSOLETE. Binding to an identical actin monomer to form a homodimer.	tmpzr1t_l9r_go_relaxed.owl	actin dimerization activity|actin polymerizing activity|actin homodimerization activity					This term was made obsolete because it was added in error; formation of an actin dimer is simply a transient step in the polymerization of actin. Also, this term may not represent a real molecular function in GO, but rather that a gene product (actin itself) is part of an actin homodimer transient protein complex.					True			molecular_function											owl:Class	
GO:0015875	biolink:NamedThing	obsolete vitamin or cofactor transport	OBSOLETE. The directed movement of vitamins or cofactors into, out of or within a cell, or between cells.	tmpzr1t_l9r_go_relaxed.owl	vitamin or cofactor transport					This term was made obsolete because it was replaced by more specific terms.	GO:0051180				True			biological_process											owl:Class	
GO:0035949	biolink:NamedThing	obsolete positive regulation of gluconeogenesis by negative regulation of transcription from RNA polymerase II promoter	OBSOLETE. Any process that activates or increases the frequency, rate or extent of gluconeogenesis by stopping, preventing, or reducing the frequency, rate or extent of transcription from an RNA polymerase II promoter.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of glucose biosynthesis by downregulation of transcription from RNA polymerase II promoter|positive regulation of gluconeogenesis by downregulation of transcription from RNA polymerase II promoter|positive regulation of gluconeogenesis by negative regulation of transcription from Pol II promoter|positive regulation of glucose biosynthesis by negative regulation of transcription from Pol II promoter|positive regulation of gluconeogenesis by down regulation of transcription from RNA polymerase II promoter|positive regulation of glucose biosynthetic process by down regulation of transcription from RNA polymerase II promoter|positive regulation of glucose biosynthetic process by downregulation of transcription from RNA polymerase II promoter|positive regulation of glucose biosynthetic process by down-regulation of transcription from RNA polymerase II promoter|positive regulation of glucose biosynthesis by negative regulation of transcription from RNA polymerase II promoter|positive regulation of glucose biosynthetic process by negative regulation of transcription from RNA polymerase II promoter|positive regulation of glucose biosynthetic process by negative regulation of transcription from Pol II promoter|positive regulation of gluconeogenesis by inhibition of transcription from RNA polymerase II promoter|positive regulation of gluconeogenesis by down-regulation of transcription from RNA polymerase II promoter|positive regulation of glucose biosynthesis by down-regulation of transcription from RNA polymerase II promoter|positive regulation of glucose biosynthesis by down regulation of transcription from RNA polymerase II promoter					This term was obsoleted because it represents a GO-CAM model.		bf			True			biological_process											owl:Class	
GO:0009935	biolink:NamedThing	obsolete nutrient import	OBSOLETE. The directed movement of nutrients into a cell or organelle.	tmpzr1t_l9r_go_relaxed.owl	nutrient import|nutrient uptake					This term was made obsolete because "nutrient" is not defined, and does not have a consistent meaning.	GO:0006810				True			biological_process											owl:Class	
GO:1902581	biolink:NamedThing	obsolete multi-organism cellular localization	OBSOLETE. A cellular localization which involves another organism.	tmpzr1t_l9r_go_relaxed.owl	multi organism cellular localization	https://github.com/geneontology/go-ontology/issues/21459				This term was obsoleted because there is no evidence that this process exists.		jl	2013-12-18T14:04:41Z		True			biological_process											owl:Class	
GO:0052401	biolink:NamedThing	obsolete induction by organism of defense-related symbiont reactive oxygen species production	OBSOLETE. The activation by an organism of the production of reactive oxygen species as part of the defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	induction by organism of defense-related symbiont ROS production|activation by organism of defense-related symbiont ROS production|activation by organism of defense-related symbiont reactive oxidative species production|activation by organism of defense-related symbiont ROI production|activation by organism of defense-related symbiont reactive oxygen intermediate production|induction by organism of defense-related symbiont reactive oxygen intermediate production|induction by organism of defense-related symbiont metabolic burst|activation by organism of defense-related symbiont oxidative burst|activation by organism of defense-related symbiont metabolic burst|induction by organism of defense-related symbiont oxidative burst|induction by organism of defense-related symbiont AOS production|activation by organism of defense-related symbiont respiratory burst|induction by organism of defense-related symbiont ROI production|activation by organism of defense-related symbiont reactive oxygen species production|induction by organism of defense-related symbiont respiratory burst|induction by organism of defense-related symbiont active oxygen species production|activation by organism of defense-related symbiont active oxygen species production|induction by organism of defense-related symbiont reactive oxygen species production|activation by organism of defense-related symbiont AOS production					This term was made obsolete because it does not represent a real biological process.					True			biological_process											owl:Class	
GO:0003377	biolink:NamedThing	obsolete regulation of apoptosis by sphingosine-1-phosphate signaling pathway	OBSOLETE. A sphingosine-1-phosphate signaling pathway that modulates the rate, frequency, or extent of apoptosis.	tmpzr1t_l9r_go_relaxed.owl	regulation of apoptosis by sphingolipid signaling pathway|regulation of apoptosis by sphingolipid signalling pathway					The reason for obsoletion is that this term represents a GO-CAM model.		dph	2009-12-09T06:32:22Z		True			biological_process											owl:Class	
GO:0009980	biolink:NamedThing	obsolete glutamate carboxypeptidase activity	OBSOLETE. Catalysis of the release of C-terminal glutamate residues from a wide range of N-acylating groups, including peptidyl, aminoacyl, benzoyl, benzyloxycarbonyl, folyl and pteroyl groups.	tmpzr1t_l9r_go_relaxed.owl	carboxypeptidase G2 activity|N-pteroyl-L-glutamate hydrolase activity|carboxypeptidase G1 activity|carboxypeptidase G activity|glutamyl carboxypeptidase activity|glutamate carboxypeptidase activity			GO:0004180		This term was made obsolete because it represents a gene product, and the substrate specificity it refers to is not cleanly defined.					True			molecular_function											owl:Class	
RO:0002334	biolink:NamedThing	regulated by		tmpzr1t_l9r_go_relaxed.owl					RO:0002334									external									regulated_by			
GO:0100032	biolink:NamedThing	obsolete positive regulation of phospholipid biosynthetic process by transcription from RNA polymerase II promoter	OBSOLETE. Any transcription from RNA polymerase II promoter process that positively regulates phospholipid biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it represents a GO-CAM model.		cjm	2015-04-02T04:13:19Z		True			biological_process											owl:Class	
RO:0002356	biolink:NamedThing	results in specification of		tmpzr1t_l9r_go_relaxed.owl					RO:0002356									external									results_in_specification_of			
GO:0019109	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0031611	biolink:NamedThing	obsolete ER proteasome regulatory particle, base subcomplex	OBSOLETE. The subunits of the regulatory particle that directly associate with the core complex of a proteasome located in the endoplasmic reticulum of a cell.	tmpzr1t_l9r_go_relaxed.owl						This term was made obsolete because there is no evidence in the literature of its existence.					True			cellular_component											owl:Class	
GO:0016839	biolink:NamedThing	obsolete other carbon-oxygen lyase activity	OBSOLETE. Catalysis of the cleavage of a carbon-oxygen bond. Enzymes with this activity are 'miscellaneous' carbon-oxygen lyases that cannot be grouped into one of the specific subclasses of the carbon-oxygen lyases.	tmpzr1t_l9r_go_relaxed.owl	other carbon-oxygen lyase activity					This term was made obsolete because it was an unnecessary grouping term.	GO:0016835				True			molecular_function											owl:Class	
GO:0085010	biolink:NamedThing	obsolete interaction with host mediated by secreted substance entering host via endocytosis	OBSOLETE. An interaction with the host organism mediated by a secreted substance from the symbiont entering host cells via endocytosis of the substance. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it conflated the process in which a gene product is involved with the secretion system by which it reaches its target.		jl	2010-02-10T03:12:31Z		True			biological_process											owl:Class	
GO:0006126	biolink:NamedThing	obsolete other pathways of electron transport	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	other pathways of electron transport			GO:0022900		This term was made obsolete because it was an unnecessary grouping term.					True			biological_process											owl:Class	
GO:0044049	biolink:NamedThing	obsolete interaction with host via protein secreted by type VI secretion system	OBSOLETE. An interaction with the host organism mediated by a substance secreted by the other (symbiont) organism via a type VI secretion system. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it conflated the process in which a gene product is involved with the secretion system by which it reaches its target.					True			biological_process											owl:Class	
GO:0007109	biolink:NamedThing	obsolete cytokinesis, completion of separation	OBSOLETE. The process of finishing cell separation, which results in two physically separated cells.	tmpzr1t_l9r_go_relaxed.owl	cytokinesis, completion of separation|completion of separation involved in cytokinesis					This term was obsoleted because it was vaguely defined and had very likely been used in error. Consider the child terms of cytokinesis related to ring positioning, assembly, ring constriction etc. which would be more appropriate.					True			biological_process											owl:Class	
GO:0097755	biolink:NamedThing	obsolete positive regulation of blood vessel diameter	OBSOLETE. Any process that increases the diameter of blood vessels.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of vasodilation					This term was obsoleted because it corresponded to an existing term, GO:0042311 ; vasodilation.		pr	2017-02-08T15:33:21Z		True			biological_process											owl:Class	
GO:0005808	biolink:NamedThing	obsolete Golgi-plasma membrane transport vesicle	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	Golgi-plasma membrane transport vesicle					This term was made obsolete as part of a general reorganization of vesicle and vesicle coat terms; a personal communication from John Armstrong indicated that a replacement term was not required, as TGN-Golgi transport is likely to be mediated by tubules rather than vesicles.	GO:0030133				True			cellular_component											owl:Class	
GO:0075309	biolink:NamedThing	obsolete negative regulation of growth or development of symbiont on or near host surface	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the increase in the symbiont's size or mass, or its progression from an initial condition to a later condition, on or near the cells or tissues of the host organism.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of growth or development of symbiont on or near host surface					This term was made obsolete because it contained a conjunction (or).					True			biological_process											owl:Class	
RO:0002233	biolink:NamedThing	has input		tmpzr1t_l9r_go_relaxed.owl					RO:0002233									external									has_input			
GO:2000976	biolink:NamedThing	obsolete regulation of transcription from RNA polymerase II promoter involved in detection of glucose	OBSOLETE. Any regulation of transcription from RNA polymerase II promoter that is involved in detection of glucose.	tmpzr1t_l9r_go_relaxed.owl	regulation of transcription from Pol II promoter involved in detection of glucose|regulation of gene-specific transcription from RNA polymerase II promoter involved in glucose detection|regulation of global transcription from Pol II promoter involved in detection of glucose|regulation of transcription from RNA polymerase II promoter involved in glucose detection|global transcription regulation from Pol II promoter involved in glucose detection|regulation of global transcription from Pol II promoter involved in glucose perception|regulation of transcription from RNA polymerase II promoter, global involved in glucose sensing|regulation of gene-specific transcription from RNA polymerase II promoter involved in glucose perception|regulation of transcription from Pol II promoter involved in glucose sensing|regulation of transcription from RNA polymerase II promoter, global involved in glucose perception|global transcription regulation from Pol II promoter involved in detection of glucose|regulation of gene-specific transcription from RNA polymerase II promoter involved in detection of glucose|regulation of transcription from RNA polymerase II promoter, global involved in glucose detection|regulation of transcription from Pol II promoter involved in glucose perception|regulation of transcription from RNA polymerase II promoter involved in glucose sensing|regulation of global transcription from Pol II promoter involved in glucose sensing|regulation of transcription from RNA polymerase II promoter involved in glucose perception|regulation of gene-specific transcription from RNA polymerase II promoter involved in glucose sensing|global transcription regulation from Pol II promoter involved in glucose perception|regulation of global transcription from Pol II promoter involved in glucose detection|global transcription regulation from Pol II promoter involved in glucose sensing|regulation of transcription from RNA polymerase II promoter, global involved in detection of glucose|regulation of transcription from Pol II promoter involved in glucose detection					This term was made obsolete is that in these terms the 'involved in' process is not truly involved_in (i.e. part_of) the process but instead is causally upstream of it. We advise replacing annotations to these terms with annotations + extensions using the causally_upstream_of relation e.g. P1234 regulation of gene expression [causally_upstream_of] extracellular matrix organization.	GO:0051594|GO:0006357	vk	2011-08-02T05:06:52Z		True			biological_process											owl:Class	
GO:0003783	biolink:NamedThing	obsolete barbed-end actin capping activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	barbed-end actin capping activity			GO:0051016		This term was made obsolete because it describes a biological process.					True			molecular_function											owl:Class	
GO:0075104	biolink:NamedThing	obsolete positive regulation by host of symbiont calcium or calmodulin-mediated signal transduction	OBSOLETE. Any process in which the host organism activates, maintains or increases the frequency, rate or extent of calcium or calmodulin-mediated signal transduction in the symbiont organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	positive regulation by host of symbiont Ca++ or calmodulin-mediated signal transduction					The reason for obsoletion is that there is no evidence that the host can modulate or regulate a symbiont's signal transduction pathway.					True			biological_process											owl:Class	
GO:0018334	biolink:NamedThing	obsolete enzyme active site formation via O4'-phospho-L-tyrosine	OBSOLETE. The transient phosphorylation of peptidyl-tyrosine to form O-phospho-L-tyrosine.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/15594			RESID:AA0039	This term was obsoleted because it was created by error: O4'-phospho-L-tyrosine is a post-translational modification, see PMID:1725475.					True			biological_process											owl:Class	
GO:0030996	biolink:NamedThing	obsolete mitotic cell cycle arrest in response to nitrogen starvation	OBSOLETE. The process in which the mitotic cell cycle is halted during one of the normal phases (G1, S, G2, M) as a result of deprivation of nitrogen.	tmpzr1t_l9r_go_relaxed.owl	cell cycle arrest in response to nitrogen starvation					This term was made obsolete because it is superfluous, as only the more specific 'mitotic G1 cell cycle arrest in response to nitrogen starvation' has been observed.					True			biological_process											owl:Class	
GO:0033125	biolink:NamedThing	obsolete negative regulation of GTP catabolic process	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of GTP, guanosine triphosphate.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of GTP degradation|negative regulation of GTP breakdown|negative regulation of GTP catabolism					The reason for making this term obsolete is that it gets misused in cases where phosphates are simply being removed from a small molecule. We found no cases where these molecules genuinely underwent catabolism.	GO:0034260				True			biological_process											owl:Class	
GO:0046759	biolink:NamedThing	obsolete lytic virus budding from plasma membrane	OBSOLETE. A form of viral release in which the nucleocapsid evaginates from the host nuclear membrane system, resulting in envelopment of the virus and cell lysis.	tmpzr1t_l9r_go_relaxed.owl	lytic viral budding from plasma membrane|lytic virus budding from plasma membrane|lytic plasma membrane viral budding					This term was made obsolete because it does not appear to correspond to a real biological process.					True			biological_process											owl:Class	
GO:0072475	biolink:NamedThing	obsolete detection of stimulus involved in mitotic spindle checkpoint	OBSOLETE. The series of events in which information about whether the spindle is correctly assembled and oriented, and chromosomes are attached to the spindle, is received and converted into a molecular signal, contributing to a mitotic cell cycle spindle checkpoint.	tmpzr1t_l9r_go_relaxed.owl	mitotic cell cycle spindle checkpoint sensor mechanism|mitotic cell cycle spindle checkpoint sensor process|detection of stimulus involved in mitotic cell cycle spindle checkpoint|sensing involved in mitotic cell cycle spindle checkpoint	https://github.com/geneontology/go-ontology/issues/20976				This term was obsoleted because it corresponds to a molecular function.		mah	2010-12-09T11:49:55Z		True			biological_process											owl:Class	
GO:0045872	biolink:NamedThing	obsolete positive regulation of rhodopsin gene expression	OBSOLETE. Any process that activates or increases the frequency, rate or extent of rhodopsin gene expression.	tmpzr1t_l9r_go_relaxed.owl	up regulation of rhodopsin gene activity|positive regulation of rhodopsin gene activity|activation of rhodopsin gene activity|up-regulation of rhodopsin gene activity|stimulation of rhodopsin gene activity|upregulation of rhodopsin gene activity					This term was obsoleted because it referes to a specific gene product. The gene product should be captured as an annotation extension using 'has input'.	GO:0045944				True			biological_process											owl:Class	
GO:0009872	biolink:NamedThing	obsolete gametophytic self-incompatibility	OBSOLETE. A mechanism that functions to prevent self-fertilization in flowering plants that is determined by the diploid genotype of the parent plant. In sporophytic incompatibility the pollen does not germinate, consequently fertilization does not take place.	tmpzr1t_l9r_go_relaxed.owl	gametophytic self-incompatibility					This term was made obsolete because it represents a phenotype.					True			biological_process											owl:Class	
GO:0023055	biolink:NamedThing	obsolete signal initiation by peptide hormone	OBSOLETE. The process in which a signal is initiated by a peptide hormone.	tmpzr1t_l9r_go_relaxed.owl	signal initiation by peptide hormone					This term was made obsolete because the meaning of the term is ambiguous.	GO:0009755|GO:0005179|GO:0004879		2010-02-16T09:30:50Z		True			biological_process											owl:Class	
GO:0007627	biolink:NamedThing	obsolete larval behavior (sensu Insecta)	OBSOLETE. Behavior in a larval form of an organism, an immature organism that must undergo metamorphosis to assume adult characteristics, as seen in insects.	tmpzr1t_l9r_go_relaxed.owl	larval behavior (sensu Insecta)			GO:0030537		This term was made obsolete because there is no clear difference between the sensu Insecta term and the generic term.					True			biological_process											owl:Class	
GO:0009003	biolink:NamedThing	obsolete signal peptidase activity	OBSOLETE. Catalysis of the cleavage of a signal peptide from a protein precursor.	tmpzr1t_l9r_go_relaxed.owl	signal peptidase activity			GO:0008233		This term was made obsolete because 'signal peptide' is difficult to define unambiguously, and because the term refers to gene products.					True			molecular_function											owl:Class	
GO:0006823	biolink:NamedThing	obsolete heavy metal ion transport	OBSOLETE. The directed movement of heavy metal ions into, out of or within a cell, or between cells. Heavy metals are those that can form a coordination bond with a protein, as opposed to an alkali or alkaline-earth metal that can only form an ionic bond; this definition includes the following biologically relevant heavy metals: Cd, Co, Cu, Fe, Hg, Mn, Mo, Ni, V, W, Zn.	tmpzr1t_l9r_go_relaxed.owl	heavy metal ion transport					This term was made obsolete because 'heavy metal' is an ambiguous grouping term which has no set meaning (see Pure Appl. Chem. Vol. 74, No. 5, pp. 793-807, 2002, for more information).	GO:0030001				True			biological_process											owl:Class	
GO:0009770	biolink:NamedThing	obsolete primary charge separation in photosystem I	OBSOLETE. Energized reaction-center P700 chlorophylls on photosystem I donate an electron to a loosely bound Quinone acceptor molecule X, on the stromal surface of the thylakoid membrane. The result is charge separation; a negative charge on the stromal side of the thylakoid membrane and a positive charge on the luminal side.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it represents a mechanism, and is outside the scope of GO.					True			biological_process											owl:Class	
GO:0009492	biolink:NamedThing	obsolete 2Fe-2S electron transfer carrier	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	2Fe-2S electron transfer carrier			GO:0009055		This term was made obsolete because it refers to a class of gene products.					True			molecular_function											owl:Class	
GO:0017163	biolink:NamedThing	obsolete basal transcription repressor activity	OBSOLETE. Any transcription regulator activity that prevents or downregulates basal transcription. Basal transcription results from transcription that is controlled by the minimal complement of proteins necessary to reconstitute transcription from a minimal promoter.	tmpzr1t_l9r_go_relaxed.owl	basal transcription repressor activity					This term was obsoleted because "general/nonspecific/basal" transcription vs "specific" transcription were determined not to be separable, distinct process. Thus, terms trying to distinguish "general/nonspecific/basal" transcription from "specific" transcription were removed from both the Molecular Function and the Biological Process ontologies. In addition, this Molecular Function term was defined only in terms of the process it acts in and it does NOT convey any information about the molecular nature of the function or whether the function is based on binding DNA, on interacting with other proteins, or some other mechanism. To transfer all annotations without review, the BP term indicated is considered to be equivalent and thus the only appropriate destination for all annotations. To reannotate to a MF term, you will probably need to revisit the original literature or other primary data because this "MF" term was not defined in terms of mechanism of action and there are multiple possibilities in the revised MF structure. In reannotation, please also consider descendent terms of the suggested MF terms as a more specific term may be more appropriate than the MF terms indicated. Please be aware that you may wish to request a new term if the mechanism of action of your repressor is not yet represented or if you are annotating for an RNAP different than one for which there is a specific suggested term. Also note that if there is no information about how the gene product acts, it may be appropriate to annotate to the root term for molecular_function.	GO:0001227|GO:0045892|GO:0001217				True			molecular_function											owl:Class	
GO:0018286	biolink:NamedThing	obsolete iron incorporation into iron-sulfur cluster via hexakis-L-cysteinyl triiron trisulfide	OBSOLETE. The incorporation of iron into a 3Fe-3S iron-sulfur cluster via hexakis-L-cysteinyl triiron trisulfide. The three-iron three-sulfur cluster probably does not exist except as an intermediate form.	tmpzr1t_l9r_go_relaxed.owl	iron incorporation into iron-sulfur cluster via hexakis-L-cysteinyl triiron trisulfide|iron incorporation into iron-sulphur cluster via tris-L-cysteinyl triiron trisulphide					This term was made obsolete because the three-iron three-sulfur cluster is now thought not to exist except possibly as an intermediate form.	GO:0018283|GO:0018198				True			biological_process											owl:Class	
GO:0000200	biolink:NamedThing	obsolete inactivation of MAPK activity involved in cell wall organization or biogenesis	OBSOLETE. Any process that terminates the activity of the active enzyme MAP kinase in the context of cell wall organization or biogenesis.	tmpzr1t_l9r_go_relaxed.owl	cell wall biogenesis, inactivation of MAPK activity|cell wall biogenesis, termination of MAPK activity|inactivation of MAPK activity involved in cell wall integrity|inactivation of MAPK activity involved in cell wall organization or biogenesis|termination of MAPK activity during cell wall biogenesis	https://github.com/geneontology/go-ontology/issues/20242				This term was obsoleted because it represents a GO-CAM model.					True			biological_process											owl:Class	
GO:0043913	biolink:NamedThing	obsolete chromosome segregation-directing complex	OBSOLETE. A trimeric protein complex which in E. coli is composed of the subunits MreB, MreC and MreD. The complex directs longitudinal cell wall synthesis, maintaining cell morphology.	tmpzr1t_l9r_go_relaxed.owl	MreBCD complex|chromosome segregation directing complex|longitudinal peptidoglycan synthesis-directing complex	https://github.com/geneontology/go-ontology/issues/19794				This term was obsoleted because the three proteins mentioned in the definition are not part of the same complex.					True			cellular_component											owl:Class	
GO:0042798	biolink:NamedThing	obsolete protein neddylation during NEDD8 class-dependent protein catabolic process	OBSOLETE. Covalent attachment of the ubiquitin-like protein NEDD8 (or equivalent protein) to another protein, as a part of NEDD8-dependant protein catabolism.	tmpzr1t_l9r_go_relaxed.owl	protein neddylation during RUB1-dependent protein catabolism|protein neddylation during NEDD8 class-dependent protein degradation|protein neddylation during NEDD8 class-dependent protein catabolism|protein neddylation during NEDD8 class-dependent protein catabolic process|protein neddylation during NEDD8 class-dependent protein breakdown|protein neddylation during RUB1-dependent protein catabolic process					This term was made obsolete because NEDD8-class tags do not target proteins for proteolytic destruction.	GO:0045116				True			biological_process											owl:Class	
GO:0015342	biolink:NamedThing	obsolete zinc, iron permease activity	OBSOLETE. Catalysis of the reaction: (Zn2+ or Fe2+)(out) = (Zn2+ or Fe2+)(in), probably powered by proton motive force.	tmpzr1t_l9r_go_relaxed.owl	zinc, iron permease activity					This term was made obsolete because it represents more than one molecular function.	GO:0005385|GO:0005381				True			molecular_function											owl:Class	
GO:0075102	biolink:NamedThing	obsolete negative regulation by host of symbiont MAP kinase-mediated signal transduction	OBSOLETE. Any process in which the host organism stops, prevents, or reduces the frequency, rate or extent of the symbiont MAP kinase-mediated signal transduction. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl						The reason for obsoletion is that there is no evidence that the host can modulate or regulate a symbiont's signal transduction pathway.					True			biological_process											owl:Class	
GO:0015316	biolink:NamedThing	obsolete nitrite/nitrate porter activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	nitrite/nitrate porter activity					This term was made obsolete because it represents a multifunctional gene product.	GO:0015112|GO:0015113|GO:0015291				True			molecular_function											owl:Class	
GO:0004628	biolink:NamedThing	obsolete calcium-independent cytosolic phospholipase A2 activity	OBSOLETE. Catalysis of the reaction: phosphatidylcholine + H2O = 1-acylglycerophosphocholine + a fatty acid anion.	tmpzr1t_l9r_go_relaxed.owl	calcium-independent cytosolic phospholipase A2 activity					This term was made obsolete because it represents component and function information.	GO:0005829|GO:0047499				True			molecular_function											owl:Class	
GO:0001685	biolink:NamedThing	obsolete axonemal dynein intermediate light chain	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	axonemal dynein intermediate light chain			GO:0005858		This term was made obsolete because it represents a single gene product and not a complex.					True			cellular_component											owl:Class	
GO:0010539	biolink:NamedThing	obsolete Hsp27 protein inhibitor activity	OBSOLETE. Stops, prevents or reduces the activity of the Hsp27 molecular chaperone.	tmpzr1t_l9r_go_relaxed.owl	Hsp27 protein inhibitor activity			GO:0051008		This term was made obsolete because it refers to a non-existent molecular function term, 'Hsp27 protein activity'.	GO:0051787|GO:0006457|GO:0051082				True			molecular_function											owl:Class	
GO:0016873	biolink:NamedThing	obsolete other isomerase activity	OBSOLETE. A grouping term for isomerases that cannot be more accurately categorized.	tmpzr1t_l9r_go_relaxed.owl	other isomerase activity					This term was made obsolete because it was an unnecessary grouping term.	GO:0016853				True			molecular_function											owl:Class	
GO:1903151	biolink:NamedThing	obsolete carbohydrate transmembrane transporter activity involved in carbohydrate import into cell	OBSOLETE. Any carbohydrate transmembrane transporter activity that is involved in carbohydrate import into cell.	tmpzr1t_l9r_go_relaxed.owl	sugar transporter involved in carbohydrate import into cell|carbohydrate transmembrane transporter activity involved in carbohydrate import into cell					This term was obsoleted at the TermGenie Gatekeeper stage.		dos	2014-07-09T11:55:42Z		True			molecular_function											owl:Class	
GO:0000067	biolink:NamedThing	obsolete DNA replication and chromosome cycle	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	DNA replication and chromosome cycle					This term was made obsolete because it has been superseded by more accurate terms to represent the biological processes occurring, and it is not clear that this term represents a useful entity.	GO:0006260|GO:0007059|GO:0051276				True			biological_process											owl:Class	
GO:0001152	biolink:NamedThing	obsolete transcription factor activity, RNA polymerase III type 1 promoter sequence-specific binding, TFIIIC recruiting	OBSOLETE. The function of binding to a specific DNA sequence motif in a type 1 RNA polymerase III (Pol III) promoter in order to recruit the transcription factor TFIIIC to the promoter.	tmpzr1t_l9r_go_relaxed.owl	type 1 RNA polymerase III promoter recognition|RNA polymerase III type 1 promoter sequence-specific DNA binding TFIIIC recruiting transcription factor activity|TFIIIA activity					This term was made obsolete in the 2018 Transcription branch revision. This represents the activity of TFIIIA only.		krc	2011-01-27T04:18:21Z		True			molecular_function											owl:Class	
GO:1900423	biolink:NamedThing	obsolete positive regulation of mating type switching by positive regulation of transcription from RNA polymerase II promoter	OBSOLETE. A positive regulation of transcription from RNA polymerase II promoter that results in positive regulation of mating type switching.	tmpzr1t_l9r_go_relaxed.owl	stimulation of mating type switching by positive regulation of transcription from RNA polymerase II promoter|up regulation of mating type switching by positive regulation of transcription from RNA polymerase II promoter|activation of mating type switching by positive regulation of transcription from RNA polymerase II promoter|up-regulation of mating type switching by positive regulation of transcription from RNA polymerase II promoter|upregulation of mating type switching by positive regulation of transcription from RNA polymerase II promoter					This term was obsoleted because it represents a GO-CAM model.		krc	2012-04-24T05:50:51Z		True			biological_process											owl:Class	
GO:1905507	biolink:NamedThing	obsolete cytoplasmic sequestering of protein involved in mitotic G2 DNA damage checkpoint	OBSOLETE. Any cytoplasmic sequestering of protein that is involved in mitotic G2 DNA damage checkpoint.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it represents a GO-CAM model.		vw	2016-09-28T12:20:28Z		True			biological_process											owl:Class	
GO:0103113	biolink:NamedThing	obsolete glucosyl-oleandomycin-exporting ATPase activity	OBSOLETE. Catalysis of the reaction: glucosyl-oleandomycin + ATP + H2O <=> glucosyl-oleandomycin + ADP + hydrogenphosphate + H+.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:TRANS-RXN-220	This term was obsoleted because it represents a substrate-specific version of the general term GO:0008559 ATPase-coupled xenobiotic transmembrane transporter activity.					True			molecular_function											owl:Class	
GO:0030830	biolink:NamedThing	obsolete negative regulation of cGMP catabolic process	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of cGMP.	tmpzr1t_l9r_go_relaxed.owl	down regulation of cGMP catabolic process|down-regulation of cGMP catabolic process|downregulation of cGMP catabolic process|negative regulation of cGMP degradation|negative regulation of cGMP breakdown|negative regulation of cGMP catabolism|inhibition of cGMP catabolic process					The reason for obsoletion is that the term represents the regulation of a signaling pathway, and not regulation of metabolism.					True			biological_process											owl:Class	
GO:1901144	biolink:NamedThing	obsolete insulin biosynthetic process	OBSOLETE. The chemical reactions and pathways resulting in the formation of insulin.	tmpzr1t_l9r_go_relaxed.owl	insulin biosynthetic process|insulin anabolism|insulin synthesis|insulin biosynthesis|insulin formation							pm	2012-07-13T12:33:10Z		True			biological_process											owl:Class	
GO:0006838	biolink:NamedThing	obsolete allantoin/allantoate transport	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	allantoin/allantoate transport					This term was made obsolete because it is a composite term that represents two individual processes.	GO:0015719|GO:0015720				True			biological_process											owl:Class	
GO:0100051	biolink:NamedThing	obsolete positive regulation of meiotic nuclear division by transcription from RNA polymerase II promoter	OBSOLETE. Any transcription from RNA polymerase II promoter process that positively regulates meiotic nuclear division.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it represents a GO-CAM model.		cjm	2015-04-02T04:13:19Z		True			biological_process											owl:Class	
GO:0052184	biolink:NamedThing	obsolete modulation by organism of symbiont hormone or growth regulator levels	OBSOLETE. The alteration by an organism of the levels of hormones or growth regulators in the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	modulation by organism of symbiont hormone or growth regulator levels					This term was made obsolete because it does not represent a real biological process.					True			biological_process											owl:Class	
GO:0023018	biolink:NamedThing	obsolete T cell activation of signal transmission via diffusible molecule	OBSOLETE. The process in which signal transmission via a diffusible molecule is initiated by a T cell.	tmpzr1t_l9r_go_relaxed.owl	T cell activation of signal transmission via diffusible molecule					This term was made obsolete because the meaning of the term is ambiguous.			2010-02-16T09:30:50Z		True			biological_process											owl:Class	
GO:0030086	biolink:NamedThing	obsolete PSII associated light-harvesting complex II, core complex, LHCIIa subcomplex	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	PSII associated light-harvesting complex II, core complex, LHCIIa subcomplex			GO:0009655		This term was made obsolete because the 'complex' it refers to contains only one gene product.					True			cellular_component											owl:Class	
GO:0017165	biolink:NamedThing	obsolete dipeptidase E activity	OBSOLETE. Catalysis of the hydrolysis of dipeptides Asp-Xaa; does not act on peptides with N-terminal Glu, Asn or Gln, nor does it cleave isoaspartyl peptides.	tmpzr1t_l9r_go_relaxed.owl	aspartyl dipeptidase activity|dipeptidase E activity|peptidase E activity|PepE gene product (Salmonella typhimurium) activity|alpha-aspartyl dipeptidase activity			GO:0016805		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0043835	biolink:NamedThing	obsolete uracil/thymine dehydrogenase activity	OBSOLETE. Catalysis of the reactions: uracil + H2O + acceptor = barbiturate + reduced acceptor; and thymine + H2O + acceptor = 5-methylbarbiturate + reduced acceptor.	tmpzr1t_l9r_go_relaxed.owl	uracil oxidase activity|uracil-thymine oxidase activity|uracil/thymine dehydrogenase activity|uracil:acceptor oxidoreductase activity				EC:1.17.99.4	This term was made obsolete because it represents two separate molecular functions.	GO:0050383|GO:0052620				True			molecular_function											owl:Class	
GO:0044132	biolink:NamedThing	obsolete development of symbiont on or near host	OBSOLETE. The progression of a symbiont from an initial condition to a later condition, within the cells or tissues of its host organism.	tmpzr1t_l9r_go_relaxed.owl						The reason for obsoletion is this term represents both a process and a component.		jl	2009-08-04T03:36:02Z		True			biological_process											owl:Class	
GO:1900528	biolink:NamedThing	obsolete regulation of cell shape involved in G1 to G0 transition	OBSOLETE. Any regulation of cell shape that is involved in G1 to G0 transition.	tmpzr1t_l9r_go_relaxed.owl	regulation of cell shape involved in G1 to G0 transition|regulation of cell shape involved in stationary phase|regulation of cell shape involved in establishment of cell quiescence|regulation of cell shape involved in cell cycle quiescence|regulation of cell shape involved in G1/G0 transition					This term was made obsolete because it represents a phenotype.		al	2012-05-08T10:42:45Z		True			biological_process											owl:Class	
GO:0039565	biolink:NamedThing	obsolete suppression by virus of host STAT1 activity by positive regulation of STAT1 catabolic process	OBSOLETE. Any process in which a virus stops, prevents, or reduces the activity of host STAT1 (signal transducer and activator of transcription-1) by promoting the ubiquitin-dependent degradation of STAT1, mediated by the proteasome.	tmpzr1t_l9r_go_relaxed.owl	targeting STAT1 for proteasome-mediated degradation|promotion by virus of proteosome-dependent STAT1 degradation|suppression by virus of host STAT1 activity by positive promotion of STAT1 proteasome-mediated degradation					The reason for obsoleting this term is that it is too specific. The exact molecular roles of the individual proteins should be captured separately.		bf	2012-03-12T02:57:36Z		True			biological_process											owl:Class	
GO:0008004	biolink:NamedThing	obsolete lamina reticularis	OBSOLETE. A layer of the basal lamina that contains collagen fibrils and connects the basal lamina to the underlying connective tissue.	tmpzr1t_l9r_go_relaxed.owl				GO:0005604		This term was obsoleted because as a layer of the basement membrane, the lamina reticularis is thought to be an artefact. See PMID:24137544 and PMID:8061357.					True			cellular_component											owl:Class	
GO:0015983	biolink:NamedThing	obsolete symport	OBSOLETE. The process of solute translocation in which two solutes equilibrate across an osmotic barrier, and the translocation of one solute is coupled to the translocation of the other in the same direction.	tmpzr1t_l9r_go_relaxed.owl	symport			GO:0015293		This term was made obsolete because it represents a molecular function rather than a biological process.					True			biological_process											owl:Class	
GO:0030191	biolink:NamedThing	obsolete Hsp70/Hsc70 protein inhibitor activity	OBSOLETE. Stops, prevents or reduces the activity of chaperones of the Hsp70/Hsc70 class.	tmpzr1t_l9r_go_relaxed.owl	Hsp70/Hsc70 protein inhibitor activity					This term was made obsolete because it refers to a non-existent molecular function term, 'Hsp70/Hsc70 protein activity'.	GO:0051787|GO:0006457|GO:0051082				True			molecular_function											owl:Class	
GO:0009874	biolink:NamedThing	obsolete sporophytic self-incompatibility	OBSOLETE. A mechanism that functions to prevent self-fertilization in flowering plants that is determined by the diploid genotype of the parent plant. In sporophytic incompatibility the pollen does not germinate, consequently fertilization does not take place.	tmpzr1t_l9r_go_relaxed.owl	sporophytic self-incompatibility					This term was made obsolete because it represents a phenotype.					True			biological_process											owl:Class	
GO:0042028	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0016718	biolink:NamedThing	obsolete oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, miscellaneous	OBSOLETE. A grouping term for oxidoreductases, acting on paired donors with incorporation or reduction of molecular oxygen, that cannot be more accurately categorized.	tmpzr1t_l9r_go_relaxed.owl	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, miscellaneous					This term was made obsolete because it was an unnecessary grouping term.	GO:0016705				True			molecular_function											owl:Class	
GO:1990507	biolink:NamedThing	obsolete ATP-independent chaperone mediated protein folding	OBSOLETE. The process of inhibiting aggregation and assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure that is dependent on interaction with a chaperone, and independent of ATP hydrolysis.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/21930				This term was obsoleted because it represents a molecular function.	GO:0044183|GO:0006457	rb	2014-10-01T23:55:05Z		True			biological_process											owl:Class	
GO:0010195	biolink:NamedThing	obsolete microRNA biosynthetic process	OBSOLETE. The chemical reactions and pathways resulting in the formation of microRNA, a large family of 21-22 nucleotide non-coding RNAs with presumed post-transcriptional regulatory activity.	tmpzr1t_l9r_go_relaxed.owl	microRNA biosynthesis|microRNA biosynthetic process|microRNA formation|miRNA biosynthesis|miRNA biosynthetic process|microRNA synthesis|microRNA anabolism			GO:0035196		This term was made obsolete because it represents a process that is not known to occur.					True			biological_process											owl:Class	
GO:0005207	biolink:NamedThing	obsolete extracellular matrix glycoprotein	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	extracellular matrix glycoprotein					This term was made obsolete because it describes localization and modification rather than activity.	GO:0005201				True			molecular_function											owl:Class	
GO:0016468	biolink:NamedThing	obsolete sodium-translocating F-type ATPase activity	OBSOLETE. Catalysis of the reaction: ATP + H2O + Na+(in) = ADP + phosphate + Na+(out). Found in eukaryotic mitochondria and chloroplasts and in bacteria.	tmpzr1t_l9r_go_relaxed.owl	sodium-translocating F-type ATPase activity|ATP synthase					This term was made obsolete because it represents a gene product.	GO:0046932|GO:0046962				True			molecular_function											owl:Class	
GO:0075158	biolink:NamedThing	obsolete negative regulation of G protein-coupled receptor signaling pathway in response to host	OBSOLETE. Any process in which the symbiont organism stops, prevents, or reduces the frequency, rate or extent of its symbiont G protein-coupled receptor-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of G-protein coupled receptor protein signaling pathway in response to host|negative regulation of symbiont G-protein coupled receptor protein-mediated signal transduction in response to host|negative regulation of G-protein coupled receptor protein signalling pathway in response to host					This term was obsoleted because there is no evidence that this process exists.					True			biological_process											owl:Class	
GO:2000135	biolink:NamedThing	obsolete positive regulation of regulation of secondary heart field cardioblast proliferation	OBSOLETE. Any process that activates or increases the frequency, rate or extent of regulation of secondary heart field cardioblast proliferation.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of regulation of secondary heart field cardioblast proliferation|positive regulation of regulation of second heart field cardioblast proliferation					This term was made obsolete because it makes no sense and was added in error.		dph	2010-09-29T12:40:37Z		True			biological_process											owl:Class	
GO:0060852	biolink:NamedThing	obsolete regulation of transcription involved in venous endothelial cell fate commitment	OBSOLETE. Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the commitment of a cell to a specific fate and contributes to a cell adopting a venous endothelial cell fate.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it represents a GO-CAM model.	GO:0060845|GO:0006357	dph	2009-08-12T11:49:49Z		True			biological_process											owl:Class	
GO:0045865	biolink:NamedThing	obsolete regulation of recombination within rDNA repeats	OBSOLETE. Any process that modulates the frequency, rate or extent of genetic recombination within the DNA of the genes coding for ribosomal RNA.	tmpzr1t_l9r_go_relaxed.owl	regulation of recombination within rDNA repeats			GO:0000019		This term was made obsolete because it describes a substrate-specific process.					True			biological_process											owl:Class	
GO:1903993	biolink:NamedThing	obsolete negative regulation of protein stabilization	OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of protein stabilization.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of protein sequestering|inhibition of lysosomal protein stabilization|inhibition of protein stabilization activity|down-regulation of lysosomal protein stabilization|down regulation of positive regulation of protein stability|negative regulation of positive regulation of protein stability|down regulation of lysosomal protein stabilization|downregulation of protein stabilization|negative regulation of protein stabilization|down regulation of protein stabilization|down regulation of protein sequestering|inhibition of protein stabilization|down-regulation of positive regulation of protein stability|downregulation of protein sequestering|downregulation of positive regulation of protein stability|down-regulation of protein stabilization|negative regulation of lysosomal protein stabilization|down regulation of protein stabilization activity|downregulation of lysosomal protein stabilization|inhibition of positive regulation of protein stability|negative regulation of protein stabilization activity|downregulation of protein stabilization activity|negative regulation of protein sequestering|inhibition of protein sequestering|down-regulation of protein stabilization activity					This term was made obsolete because it was created in error.	GO:0031648	pga	2015-03-05T13:32:55Z		True			biological_process											owl:Class	
GO:0051858	biolink:NamedThing	obsolete avoidance of symbiont defenses	OBSOLETE. Any process, either constitutive or induced, by which an organism evades, minimizes, or suppresses the effects of its symbiont organism's defense(s). The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/14862				This term was made obsolete because it is not relevant for the host in a host-symbiont interaction.					True			biological_process											owl:Class	
GO:0051802	biolink:NamedThing	obsolete regulation of cytolysis in other organism involved in symbiotic interaction	OBSOLETE. Any process in which an organism modulates the frequency, rate or extent of the cytolysis by that organism of cells in a second organism, where the two organisms are in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	regulation of cytolysis of cells in other organism involved in symbiotic interaction|regulation of cytolysis of cells in other organism during symbiotic interaction					This term was obsoleted because it represents an unnecessary grouping class.					True			biological_process											owl:Class	
GO:0075050	biolink:NamedThing	obsolete positive regulation of symbiont cell wall strengthening involved in entry into host	OBSOLETE. Any process that activates, maintains or increases the frequency, rate or extent of symbiont cell wall strengthening during entry into host. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of symbiont cell wall strengthening during entry into host					The reason for the obsoletion is that there is no evidence that those processes exist.					True			biological_process											owl:Class	
GO:0018330	biolink:NamedThing	obsolete enzyme active site formation via N6-(phospho-5'-guanosine)-L-lysine	OBSOLETE. The transient guanylylation of lysine to form N6-(phospho-5'-guanosine)-L-lysine, found in the guanylyltransferase active site of mRNA capping enzyme.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/15594			RESID:AA0228	This term was obsoleted because it represents a reaction intermediate, not a biological process, see PMID:6092377.	GO:0070568				True			biological_process											owl:Class	
GO:1990847	biolink:NamedThing	obsolete peptide pheromone transmembrane export involved in positive regulation of conjugation with cellular fusion	OBSOLETE. The directed movement of a peptide pheromone across a membrane and out of a cell by a secretion or export pathway used solely for the export of peptide pheromones that contributes to a conjugation process that results in the union of cellular and genetic information from compatible mating types.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/20310				This term was obsoleted because it represents a BP in a BP and should be captured with a GO-CAM model		al	2015-09-08T15:23:26Z		True			biological_process											owl:Class	
GO:0045427	biolink:NamedThing	obsolete enzyme active site formation via (phospho-5'-guanosine)-L-histidine	OBSOLETE. The transient guanylylation of peptidyl-histidine to form (phospho-5'-guanosine)-L-histidine.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/15594				This term was obsoleted because it represents a reaction intermediate, not a biological process, see PMID:10529169.	GO:0036428				True			biological_process											owl:Class	
GO:0075232	biolink:NamedThing	obsolete positive regulation of spore movement on or near host	OBSOLETE. Any process that activates, maintains or increases the frequency, rate or extent of spore movement on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it represented both a process and a location.					True			biological_process											owl:Class	
GO:0016466	biolink:NamedThing	obsolete hydrogen-translocating A-type ATPase activity	OBSOLETE. Catalysis of the reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out). Found in archae.	tmpzr1t_l9r_go_relaxed.owl	proton-translocating A-type ATPase activity|hydrogen-translocating A-type ATPase activity			GO:0046961		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0008268	biolink:NamedThing	obsolete receptor signaling protein tyrosine kinase signaling protein activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	receptor signaling protein tyrosine kinase signaling protein activity|receptor signalling protein tyrosine kinase signalling protein activity					This term was made obsolete because the meaning of the term is ambiguous and it incorporates process information.	GO:0035556				True			molecular_function											owl:Class	
GO:0075179	biolink:NamedThing	obsolete negative regulation of calcium or calmodulin-mediated signal transduction in response to host	OBSOLETE. Any process in which the symbiont organism stops, prevents, or reduces the frequency, rate or extent of its symbiont calcium or calmodulin-mediated signal transduction as a result of detecting host molecules in, on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of symbiont calcium or calmodulin-mediated signal transduction in response to host|negative regulation of symbiont Ca++ or calmodulin-mediated signal transduction in response to host					This term was obsoleted because there is no evidence that this process exists.					True			biological_process											owl:Class	
GO:0004584	biolink:NamedThing	obsolete dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase activity	OBSOLETE. Catalysis of the transfer of an alpha-D-mannosyl residue from dolichyl-phosphate D-mannose into membrane lipid-linked oligosaccharide.	tmpzr1t_l9r_go_relaxed.owl	dolichol phosphomannose-oligosaccharide-lipid mannosyltransferase activity|dolichyl-phosphate-D-mannose:glycolipid alpha-D-mannosyltransferase activity|oligomannosylsynthase activity	https://github.com/geneontology/go-ontology/issues/16022			MetaCyc:2.4.1.130-RXN|EC:2.4.1.130	The reason for obsoletion is that this activity has been replaced by 4 activities in EC, EC:2.4.1.258, EC:2.4.1.259, EC:2.4.1.260, and EC:2.4.1.261.	GO:0052925|GO:0052926|GO:0052918|GO:0052917				True			molecular_function											owl:Class	
GO:0005028	biolink:NamedThing	obsolete CD40 receptor activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	CD40 receptor activity					This term was made obsolete because it describes the receptor type, and not an activity.	GO:0042615				True			molecular_function											owl:Class	
GO:0004285	biolink:NamedThing	obsolete proprotein convertase 1 activity	OBSOLETE. Catalysis of the release of protein hormones, neuropeptides and renin from their precursors, generally by cleavage of -Lys-Arg-Xaa at the Arg-Xaa bond.	tmpzr1t_l9r_go_relaxed.owl	neuroendocrine convertase 1 activity|prohormone convertase 3|NEC 1 activity|prohormone convertase I activity|proprotein convertase 1 activity|PC1 activity			GO:0004252		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0100048	biolink:NamedThing	obsolete positive regulation of phosphatidylcholine biosynthetic process by transcription from RNA polymerase II promoter	OBSOLETE. Any transcription from RNA polymerase II promoter process that positively regulates phosphatidylcholine biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it represents a GO-CAM model.		cjm	2015-04-02T04:13:19Z		True			biological_process											owl:Class	
GO:2000461	biolink:NamedThing	obsolete negative regulation of eukaryotic cell surface binding	OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of eukaryotic cell surface binding.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of eukaryotic cell surface binding					This term was made obsolete because the cell surface binding terms are ambiguous grouping terms and were causing confusion.	GO:0031347|GO:1900121	yaf	2011-03-04T12:00:26Z		True			biological_process											owl:Class	
GO:0000202	biolink:NamedThing	obsolete MAPKKK cascade during sporulation (sensu Saccharomyces)	OBSOLETE. MAPKKK cascade involved in transduction of signal promoting sporulation. As in, but not restricted to, the taxon Saccharomyces (Saccharomyces, ncbi_taxonomy_id:4930).	tmpzr1t_l9r_go_relaxed.owl	MAPKKK cascade during sporulation (sensu Saccharomyces)					This term was made obsolete because it is a gene product specific term.					True			biological_process											owl:Class	
GO:1990628	biolink:NamedThing	obsolete Sigma-E factor negative regulation complex	OBSOLETE. A protein complex consisting of RseA, RseB and RpoE. It form the inactive form of the sigma-E transcription factor. In response to stress, outer membrane proteins accumulate in the periplasm and activate cleavage of RseA periplasmic domain by DegS, triggering a proteolytic cascade that frees sigma-E to activate gene expression. RseB binding to RseA prevents activated DegS from cleaving RseA. Sigma-E-mediated envelope stress response is the major pathway to ensure homeostasis in the envelope compartment of the cell.	tmpzr1t_l9r_go_relaxed.owl	RseA-RseB-RpoE complex|Sigma-E factor negative regulation complex					This term was obsoleted at the TermGenie Gatekeeper stage.		bhm	2015-02-04T15:38:37Z		True			cellular_component											owl:Class	
GO:0075333	biolink:NamedThing	obsolete positive regulation by host of symbiont adenylate cyclase-mediated signal transduction	OBSOLETE. Any process in which the host organism activates, maintains or increases the frequency, rate or extent of adenylate cyclase-mediated signal transduction in the symbiont organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl						The reason for obsoletion is that there is no evidence that the host can modulate or regulate a symbiont's signal transduction pathway.					True			biological_process											owl:Class	
GO:0015477	biolink:NamedThing	obsolete receptor porin activity	OBSOLETE. A porin of the bacterial outer membrane that forms transmembrane pores and transports relatively large molecules from the external milieu to the periplasm in an energized process. Energizing of transport across the outer membrane requires a heterotrimeric complex of proteins, the TonB-ExbB-ExbD complex, or in some cases, the TolA-TolQ-TolR complex. Energizing requires proton motive force across the cytoplasmic membrane.	tmpzr1t_l9r_go_relaxed.owl	receptor porin activity					This term was made obsolete because it combines two functions that are not linked.					True			molecular_function											owl:Class	
GO:0009354	biolink:NamedThing	obsolete dihydrolipoamide S-succinyltransferase complex	OBSOLETE. An enzyme complex that catalyzes the transfer of succinyl-CoA to dihydrolipoamide to form S-succinyldihydrolipoamide. The enzyme is a component of the multienzyme 2-oxoglutarate dehydrogenase complex.	tmpzr1t_l9r_go_relaxed.owl	dihydrolipoamide S-succinyltransferase complex					This term was made obsolete because dihydrolipoamide S-succinyltransferase itself is not a complex, it is a component of the 2-oxoglutarate dehydrogenase complex, the activity dihydrolipoamide S-succinyltransferase is contained in a single polypeptide.	GO:0045252				True			cellular_component											owl:Class	
GO:0052512	biolink:NamedThing	obsolete positive regulation by organism of hormone or growth regulator levels in symbiont	OBSOLETE. The increase by an organism of the levels of hormones or growth regulators in the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	positive modulation of hormone or growth regulator levels in symbiont|positive regulation by organism of hormone or growth regulator levels in symbiont					This term was made obsolete because it does not represent a real biological process.					True			biological_process											owl:Class	
GO:0040006	biolink:NamedThing	obsolete protein-based cuticle attachment to epithelium	OBSOLETE. Attaching of a protein-based cuticle to the epithelium underlying it.	tmpzr1t_l9r_go_relaxed.owl	cuticular attachment to epithelium|protein-based cuticle attachment to epithelium					This term was made obsolete because 'protein-based cuticle' is an unnecessary grouping term.	GO:0040004|GO:0040005				True			biological_process											owl:Class	
GO:0038070	biolink:NamedThing	obsolete MAP kinase kinase kinase activity involved in cell wall organization or biogenesis	OBSOLETE. Catalysis of the phosphorylation and activation of a MAP kinase kinase (MAPKK), as part of a MAPK signaling cascade that contributes to cell wall organization or biogenesis.	tmpzr1t_l9r_go_relaxed.owl	MAPKKK activity involved in cell wall integrity|MAP kinase kinase kinase activity involved in cell wall biogenesis|MAP3K activity involved in cell wall integrity					This term has been obsoleted because it represents a GO-CAM model rather than a single GO term.		bf	2012-01-25T03:43:46Z		True			molecular_function											owl:Class	
GO:0007550	biolink:NamedThing	obsolete establishment of dosage compensation	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	establishment of dosage compensation					This term was made obsolete because it was undefined and because there is no common mechanism of establishment of dosage compensation in different organisms.	GO:0007549				True			biological_process											owl:Class	
GO:0008369	biolink:NamedThing	obsolete molecular function	OBSOLETE. These are terms that have been removed from the active function ontology.	tmpzr1t_l9r_go_relaxed.owl						This term was made obsolete because it is unnecessary in the OBO flat file format.					True			molecular_function											owl:Class	
GO:2000579	biolink:NamedThing	obsolete positive regulation of microtubule motor activity, minus-end-directed	OBSOLETE. Any process that activates or increases the frequency, rate or extent of ATP-dependent microtubule motor activity, minus-end-directed.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of kinesin ATP phosphohydrolase (minus-end-directed)|positive regulation of minus-end-directed microtubule motor activity|positive regulation of ATP-dependent microtubule motor activity, minus-end-directed|positive regulation of minus-end-directed kinesin ATPase activity	https://github.com/geneontology/go-ontology/issues/21626				This term was obsoleted because it represents a molecular function.	GO:0140660	bf	2011-04-05T08:38:01Z		True			biological_process											owl:Class	
GO:0000039	biolink:NamedThing	obsolete plasma membrane long-chain fatty acid transporter	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	plasma membrane long-chain fatty acid transporter					This term was made obsolete because it describes a gene product and it contains component information.	GO:0005886|GO:0005324				True			molecular_function											owl:Class	
GO:0017072	biolink:NamedThing	obsolete tubulin-specific chaperone activity	OBSOLETE. Assists in the correct, non-covalent assembly of tubulin-containing structures in vivo, but is not a component of the assembled structures when performing its normal biological function.	tmpzr1t_l9r_go_relaxed.owl	tubulin-specific chaperone activity					This term was made obsolete because it represents a class of gene products and a biological process rather than a molecular function.	GO:0007021				True			molecular_function											owl:Class	
GO:0001687	biolink:NamedThing	obsolete cytoplasmic dynein heavy chain	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	cytoplasmic dynein heavy chain			GO:0005868		This term was made obsolete because it represents a single gene product and not a complex.					True			cellular_component											owl:Class	
GO:0002147	biolink:NamedThing	obsolete glucocorticoid receptor import into nucleus	OBSOLETE. The directed movement of a glucocorticoid receptor into the nucleus.	tmpzr1t_l9r_go_relaxed.owl	glucocorticoid receptor nuclear translocation					The reason for obsoletion is that all proteins are imported into the nucleus via the same mechanism, so the import of individual proteins should be captured with extensions or by GO-CAM models.	GO:0042306	hjd	2009-07-09T02:36:09Z		True			biological_process											owl:Class	
GO:0042291	biolink:NamedThing	obsolete Hub1 hydrolase activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	Hub1 hydrolase activity					This term was made obsolete because it cannot be determined what its intended meaning was, because the term name is not found in the literature.	GO:0019783				True			molecular_function											owl:Class	
GO:0005073	biolink:NamedThing	obsolete common-partner SMAD protein	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	common-partner SMAD protein					This term was made obsolete because it names a family of gene products.					True			molecular_function											owl:Class	
GO:0018089	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1990128	biolink:NamedThing	obsolete pre-primosome complex involved in replication initiation	OBSOLETE. A protein-DNA complex involved in replication initiation at the origin of replication.	tmpzr1t_l9r_go_relaxed.owl	pre-primosome complex involved in replication initiation					This term was obsoleted at the TermGenie Gatekeeper stage.		bhm	2013-06-24T10:29:39Z		True			cellular_component											owl:Class	
GO:0052392	biolink:NamedThing	obsolete induction by organism of defense-related symbiont calcium ion flux	OBSOLETE. The activation by an organism of a flux of calcium ions that occurs as part of the defense response of a symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	induction by organism of defense-related symbiont calcium ion flux|induction by organism of symbiont Ca2+ flux|activation by organism of symbiont Ca2+ flux|activation by organism of symbiont calcium ion flux					This term was made obsolete because it does not represent a real biological process.					True			biological_process											owl:Class	
GO:0031368	biolink:NamedThing	obsolete Pro-X metallocarboxypeptidase activity	OBSOLETE. Catalysis of the cleavage of a Pro-Xaa bond by a metallopeptidase mechanism to release a C-terminal amino acid.	tmpzr1t_l9r_go_relaxed.owl	carboxypeptidase P activity|membrane Pro-X carboxypeptidase activity|microsomal carboxypeptidase activity|membrane Pro-Xaa carboxypeptidase|Pro-X metallocarboxypeptidase activity				EC:3.4.17.16	This term was made obsolete because it represents a gene product.	GO:0008233|GO:0004181				True			molecular_function											owl:Class	
RO:0002348	biolink:NamedThing	results in commitment to		tmpzr1t_l9r_go_relaxed.owl					RO:0002348									external									results_in_commitment_to			
GO:1905195	biolink:NamedThing	obsolete regulation of ATPase activity, uncoupled	OBSOLETE. Any process that modulates the frequency, rate or extent of ATPase activity, uncoupled.	tmpzr1t_l9r_go_relaxed.owl	regulation of adenylpyrophosphatase activity					The reason for obsoletion is that the there is no convincing example of a protein with this function.		al	2016-05-12T08:01:20Z		True			biological_process											owl:Class	
GO:0015480	biolink:NamedThing	obsolete secretin (sensu Bacteria)	OBSOLETE. Secretins are Gram-negative bacterial outer membrane proteins that form multimeric pores through which macromolecules, usually proteins, can pass. Form homomultimeric ring structures, 10-20 subunits per complex, with large central pores (inner diameters of 5-10 nm).	tmpzr1t_l9r_go_relaxed.owl	secretin (sensu Bacteria)					This term was made obsolete because it represents a class of gene products.	GO:0045203|GO:0008320				True			molecular_function											owl:Class	
GO:0006339	biolink:NamedThing	obsolete positive regulation of transcription of homeotic gene (trithorax group)	OBSOLETE. Any process that activates or increases the frequency, rate or extent of transcription of homeotic genes of the trithorax group.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of transcription of homeotic gene (trithorax group)					This term was made obsolete because it relates to a specific gene family rather than a process.	GO:0031507|GO:0045944|GO:0045815				True			biological_process											owl:Class	
GO:0045012	biolink:NamedThing	obsolete MHC class II receptor activity	OBSOLETE. A major histocompatibility complex class II receptor. These display processed antigens from virally-infected or transformed cells. Class-II-positive cells ('antigen-presenting cells') can take up antigens from outside by endocytosis, degrade them into small peptides, and re-export the peptides (now bound to MHC class II protein) to the cell surface. These peptide-MHC class II complexes can then be recognized by specific CD4+ lymphocytes.	tmpzr1t_l9r_go_relaxed.owl	class II major histocompatibility complex antigen|major histocompatibility complex class II receptor|MHC class II receptor activity					This term was made obsolete because it was defined ambiguously, and has therefore been used incorrectly in annotations. To update annotations of gene products that act as receptors for MHC class II protein complexes, use the molecular function term 'MHC class II receptor activity ; GO:0032395'; to update annotations of gene products which are components of MHC class II protein complexes, use the cellular component term 'MHC class II protein complex ; GO:0042613'.	GO:0042613|GO:0032395				True			molecular_function											owl:Class	
GO:0070322	biolink:NamedThing	obsolete negative regulation of translation in response to nitrogen starvation	OBSOLETE. Any process that stops, prevents or reduces the rate of translation as a result of a stimulus indicating deprivation of nitrogen.	tmpzr1t_l9r_go_relaxed.owl	inhibition of translation in response to nitrogen starvation|down-regulation of translation in response to nitrogen starvation|downregulation of translation in response to nitrogen starvation|down regulation of translation in response to nitrogen starvation	https://github.com/geneontology/go-ontology/issues/19092				This term was obsoleted because it was redundant with GO:1903574 ; negative regulation of cellular response to amino acid starvation.	GO:1903574				True			biological_process											owl:Class	
GO:0023039	biolink:NamedThing	obsolete signal initiation by physical damage	OBSOLETE. The process in which a physical damage signal causes activation of a receptor.	tmpzr1t_l9r_go_relaxed.owl	signal initiation by physical damage					This term was made obsolete because the meaning of the term is ambiguous.	GO:0033554|GO:0038023		2010-02-16T09:30:50Z		True			biological_process											owl:Class	
GO:0039541	biolink:NamedThing	obsolete suppression by virus of host RIG-I via RIG-I binding	OBSOLETE. Any process in which a virus stops, prevents, or reduces the activity of RIG-I (also known as DDX58) by binding to RIG-I itself.	tmpzr1t_l9r_go_relaxed.owl	inhibition by virus of host DDX58:MAVS binding					The reason for obsoleting this term is that it is too specific. The exact molecular roles of the individual proteins should be captured separately.		bf	2012-01-19T02:14:20Z		True			biological_process											owl:Class	
GO:0075088	biolink:NamedThing	obsolete positive regulation by host of symbiont G protein-coupled receptor signal transduction	OBSOLETE. Any process in which the host organism activates, maintains or increases the frequency, rate or extent of the symbiont G protein-coupled receptor signal transduction. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	positive regulation by host of symbiont G-protein coupled receptor protein signal transduction					The reason for obsoletion is that there is no evidence that the host can modulate or regulate a symbiont's signal transduction pathway.					True			biological_process											owl:Class	
GO:1901638	biolink:NamedThing	obsolete copper ion import into ascospore-type prospore	OBSOLETE. Any copper ion import that takes place in ascospore-type prospore.	tmpzr1t_l9r_go_relaxed.owl	copper ion import into ascospore-type prospore|copper ion uptake in ascospore-type prospore					https://sourceforge.net/tracker/index.php?func=detail&aid=3510080&group_id=36855&atid=440764		al	2012-11-15T15:44:04Z		True			biological_process											owl:Class	
GO:0017142	biolink:NamedThing	obsolete toxin susceptibility/resistance	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	toxin susceptibility/resistance			GO:0009636		This term was made obsolete because 'susceptibility/resistance' implies a phenotype rather than a biological process.					True			biological_process											owl:Class	
GO:0005194	biolink:NamedThing	obsolete cell adhesion molecule activity	OBSOLETE. Mediates the adhesion of the cell to other cells or to the extracellular matrix.	tmpzr1t_l9r_go_relaxed.owl	cell adhesion molecule activity					This term was made obsolete because it represents gene products involved in the biological process of cell adhesion.	GO:0098631|GO:0005515|GO:0007155|GO:0050839|GO:0016021|GO:0030246|GO:0005102				True			molecular_function											owl:Class	
GO:0052195	biolink:NamedThing	obsolete movement on or near other organism involved in symbiotic interaction	OBSOLETE. The directed movement of an organism or motile cell on or near a second organism, where the two organisms are in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	movement on or near other organism during symbiotic interaction					This term was obsoleted because it represented both a process and a location.					True			biological_process											owl:Class	
GO:2000578	biolink:NamedThing	obsolete negative regulation of microtubule motor activity, minus-end-directed	OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of ATP-dependent microtubule motor activity, minus-end-directed.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of minus-end-directed kinesin ATPase activity|negative regulation of kinesin ATP phosphohydrolase (minus-end-directed)|negative regulation of minus-end-directed microtubule motor activity|negative regulation of ATP-dependent microtubule motor activity, minus-end-directed	https://github.com/geneontology/go-ontology/issues/21626				This term was obsoleted because it represents a molecular function.	GO:0140661	bf	2011-04-05T08:37:57Z		True			biological_process											owl:Class	
GO:0004235	biolink:NamedThing	obsolete matrilysin activity	OBSOLETE. Catalysis of the cleavage of Ala14-Leu15 and Tyr16-Leu17 in B chain of insulin. No action on collagen types I, II, IV and V. Cleaves gelatin chain alpha-2(I) > alpha-1(I).	tmpzr1t_l9r_go_relaxed.owl	matrin activity|PUMP|uterine metalloendopeptidase activity|matrix metalloproteinase pump 1|MMP-7|PUMP-1 proteinase activity|metalloproteinase pump-1|matrilysin activity|PUMP-1 activity|MMP|putative (or punctuated) metalloproteinase-1 activity|MMP 7|putative metalloproteinase activity|matrix metalloproteinase 7 activity			GO:0004222		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0052464	biolink:NamedThing	obsolete modulation by organism of symbiont programmed cell death	OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of programmed cell death in a symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	modulation of symbiont PCD|modulation of symbiont HR|modulation of symbiont hypersensitive response|modulation by organism of symbiont programmed cell death					This term was made obsolete because it does not represent a real biological process.					True			biological_process											owl:Class	
GO:0009499	biolink:NamedThing	obsolete monocluster bacterial-type ferredoxin	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	monocluster bacterial-type ferredoxin			GO:0009055		This term was made obsolete because it does not represent a function.					True			molecular_function											owl:Class	
GO:0030635	biolink:NamedThing	obsolete acetate derivative metabolic process	OBSOLETE. The chemical reactions and pathways involving derivatives of acetic acid.	tmpzr1t_l9r_go_relaxed.owl	acetate derivative metabolic process|acetate derivative metabolism					This term was made obsolete because it is an unnecessary grouping term, and has been replaced by terms to describe metabolism of specific compounds.	GO:1900619				True			biological_process											owl:Class	
GO:0005810	biolink:NamedThing	obsolete endocytotic transport vesicle	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	endocytotic transport vesicle			GO:0030139		This term was made obsolete as part of a general reorganization of vesicle and vesicle coat terms; its position in the ontology suggested that a new term was required.					True			cellular_component											owl:Class	
GO:0015000	biolink:NamedThing	obsolete polyferredoxin	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	polyferredoxin			GO:0009055		This term was made obsolete because it does not represent a function.					True			molecular_function											owl:Class	
GO:0007081	biolink:NamedThing	obsolete mitotic sister-chromatid adhesion release	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	mitotic sister-chromatid adhesion release					This term was made obsolete because the term name is ambiguous and appears to encompass two processes.	GO:0007064|GO:0000070				True			biological_process											owl:Class	
GO:1902583	biolink:NamedThing	obsolete multi-organism intracellular transport	OBSOLETE. An intracellular transport which involves another organism.	tmpzr1t_l9r_go_relaxed.owl	multi organism intracellular transport					This term was obsoleted because there is no evidence that this process exists.		jl	2013-12-18T14:04:58Z		True			biological_process											owl:Class	
GO:0070688	biolink:NamedThing	obsolete MLL5-L complex	OBSOLETE. A protein complex that can methylate lysine-4 of histone H3 and plays an essential role in retinoic-acid-induced granulopoiesis. MLL5 is the catalytic methyltransferase subunit, and the complex also contains serine/threonine kinase 38 (STK38), protein phosphatase 1 catalytic subunits, the host cell factor-1 N-terminal subunit, beta-actin, and O-GlcNAc transferase; the human genes encoding the subunits are MLL5, STK38, PPP1CA, PPP1CB, PPP1CC, HCFC1, ACTB and OGT, respectively.	tmpzr1t_l9r_go_relaxed.owl						This term was made obsolete because there is no evidence for the existence of this complex.		mah	2009-06-03T11:50:18Z		True			cellular_component											owl:Class	
GO:0016700	biolink:NamedThing	obsolete oxidoreductase activity, acting on hydrogen as donor, other acceptors	OBSOLETE. Catalysis of an oxidation-reduction (redox) reaction in which hydrogen is the electron donor and reduces an acceptor other than a cytochrome, an iron-sulfur protein, NAD, NADP or a quinone or similar compound.	tmpzr1t_l9r_go_relaxed.owl	oxidoreductase activity, acting on hydrogen as donor, other acceptors					This term was made obsolete because it was an unnecessary grouping term.	GO:0016695				True			molecular_function											owl:Class	
GO:0030803	biolink:NamedThing	obsolete negative regulation of cyclic nucleotide biosynthetic process	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cyclic nucleotides.	tmpzr1t_l9r_go_relaxed.owl	down-regulation of cyclic nucleotide biosynthetic process|down regulation of cyclic nucleotide biosynthetic process|negative regulation of cyclic nucleotide formation|negative regulation of cyclic nucleotide synthesis|negative regulation of cyclic nucleotide anabolism|negative regulation of cyclic nucleotide biosynthesis|inhibition of cyclic nucleotide biosynthetic process|downregulation of cyclic nucleotide biosynthetic process					The reason for obsoletion is that this term represents the regulation of a signaling pathway, not regulation of metabolism.					True			biological_process											owl:Class	
GO:0015443	biolink:NamedThing	obsolete sodium-transporting two-sector ATPase activity	OBSOLETE. Catalysis of the reaction: ATP + H2O + Na+(in) = ADP + phosphate + Na+(out).	tmpzr1t_l9r_go_relaxed.owl	sodium-transporting two-sector ATPase activity					This term was made obsolete because it refers to a bifunctional gene product.	GO:0046932|GO:0046962				True			molecular_function											owl:Class	
GO:0005532	biolink:NamedThing	obsolete mannose binding lectin	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	mannose binding lectin|mannose receptor					This term was made obsolete because it refers to a class of gene products.	GO:0005537|GO:0007157				True			molecular_function											owl:Class	
GO:0001309	biolink:NamedThing	obsolete age-dependent telomere shortening	OBSOLETE. Progressive reduction in length of the telomeres, the termini of eukaryotic chromosomes, that occurs as part of the cellular aging process.	tmpzr1t_l9r_go_relaxed.owl	age-dependent telomere shortening					This term was made obsolete because it represents a phenotype.	GO:1903824				True			biological_process											owl:Class	
GO:0050063	biolink:NamedThing	obsolete low-density-lipoprotein particle receptor kinase activity	OBSOLETE. Catalysis of the reaction: ATP + low-density lipoprotein L-serine = ADP + low-density lipoprotein O-phospho-L-serine.	tmpzr1t_l9r_go_relaxed.owl	low-density lipoprotein receptor kinase activity|STK7|low-density-lipoprotein receptor kinase (phosphorylating) activity|LDL receptor kinase activity|low-density-lipoprotein kinase activity|ATP:low-density-lipoprotein-L-serine O-phosphotransferase activity|ATP:low-density-lipoprotein receptor-L-serine O-phosphotransferase activity|[low-density lipoprotein receptor] kinase activity|low-density-lipoprotein receptor kinase activity				MetaCyc:2.7.11.29-RXN|EC:2.7.11.29	This term was made obsolete because it represents a specific gene product.					True			molecular_function											owl:Class	
GO:0052497	biolink:NamedThing	obsolete occlusion by organism of xylem in other organism involved in symbiotic interaction	OBSOLETE. The process in which an organism reduces the flow of fluid within the xylem, the tissue in plants that carries water and nutrients up from the roots to the shoot and leaves, of a second organism, where the two organisms are in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	occlusion by organism of xylem in other organism during symbiotic interaction					This term was obsoleted because it represents an unnecessary grouping class.					True			biological_process											owl:Class	
GO:0052458	biolink:NamedThing	obsolete modulation by organism of symbiont non-apoptotic programmed cell death	OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of programmed cell death in the symbiont, where programmed cell death proceeds by a non-apoptotic pathway. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	modulation by organism of symbiont non-apoptotic programmed cell death					This term was made obsolete because it does not represent a real biological process.					True			biological_process											owl:Class	
GO:0018998	biolink:NamedThing	obsolete metaxin	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	metaxin					This term was made obsolete because it represents a single gene product and not a complex.	GO:0005741				True			cellular_component											owl:Class	
GO:0008351	biolink:NamedThing	obsolete microtubule severing activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	microtubule severing activity					This term was made obsolete because it describes a biological process.	GO:0051013|GO:0008017				True			molecular_function											owl:Class	
GO:0097223	biolink:NamedThing	obsolete sperm part	OBSOLETE. Any constituent part of a sperm, a mature male germ cell that develops from a spermatid.	tmpzr1t_l9r_go_relaxed.owl						Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.	CL:0000019	pr	2012-01-25T01:19:35Z		True			cellular_component											owl:Class	
GO:0008751	biolink:NamedThing	obsolete NAD(P)H dehydrogenase	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	NAD(P)H dehydrogenase					This term was made obsolete because it is a redundant grouping term with only one child.	GO:0016651				True			molecular_function											owl:Class	
GO:0015257	biolink:NamedThing	obsolete organic anion channel activity	OBSOLETE. This term was not defined before being made obsolete.	tmpzr1t_l9r_go_relaxed.owl	organic anion channel activity					This term was made obsolete because this solute is transported by an active transporter rather than a channel.					True			molecular_function											owl:Class	
GO:0032800	biolink:NamedThing	obsolete receptor biosynthetic process	OBSOLETE. The chemical reactions and pathways resulting in the formation of a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.	tmpzr1t_l9r_go_relaxed.owl	receptor formation|receptor synthesis|receptor biosynthesis|receptor anabolism	https://github.com/geneontology/go-ontology/issues/19900				The reason for obsoletion is that those represent specific gene products, and genes annotated to those terms should be annotated to 'regulation of gene expression' or 'regulation of transcription' or some signaling term.					True			biological_process											owl:Class	
GO:0015063	biolink:NamedThing	obsolete long-wave-sensitive opsin	OBSOLETE. An opsin with maximal absorption above 500 nm.	tmpzr1t_l9r_go_relaxed.owl	long-wave-sensitive opsin					This term was made obsolete because it refers to a class of proteins.	GO:0007603|GO:0016021|GO:0009881|GO:0016918|GO:0046876				True			molecular_function											owl:Class	
GO:0052121	biolink:NamedThing	obsolete positive chemotaxis in host environment	OBSOLETE. The directed movement of a motile cell or organism towards a higher concentration of a chemical on, within or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	positive chemotaxis in response to host environment	https://github.com/geneontology/go-ontology/issues/18819				This term was obsoleted because it represents both a process and a location.					True			biological_process											owl:Class	
GO:0075163	biolink:NamedThing	obsolete positive regulation of G-protein beta subunit-mediated signal transduction in response to host	OBSOLETE. Any process in which the symbiont organism activates, maintains or increases the frequency, rate or extent of its G-protein beta subunit-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of symbiont G-protein beta subunit-mediated signal transduction in response to host					This term was obsoleted because there is no evidence that this process exists.					True			biological_process											owl:Class	
GO:0052010	biolink:NamedThing	obsolete catabolism by symbiont of host cell wall cellulose	OBSOLETE. The chemical reactions and pathways performed by an organism resulting in the breakdown of cellulose in the host cell wall. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	catabolism by organism of host cell wall cellulose	https://github.com/geneontology/go-ontology/issues/21469				This term was obsoleted because it represents a molecular function.					True			biological_process											owl:Class	
GO:0005708	biolink:NamedThing	obsolete mitotic chromosome	OBSOLETE. A chromosome involved in the process of mitosis.	tmpzr1t_l9r_go_relaxed.owl	mitotic chromosome					This term was made obsolete because it is based on a process.	GO:0000794|GO:0000793				True			cellular_component											owl:Class	
GO:0001088	biolink:NamedThing	obsolete transcription factor activity, TFIIE-class binding	OBSOLETE. Binding to a basal RNA polymerase II transcription factor of the TFIIE class in order to modulate transcription. The transcription factor may or may not also interact selectively with DNA as well.	tmpzr1t_l9r_go_relaxed.owl	TFIIE-class binding transcription factor activity					This term was obsoleted because it represents two separate functions. The corresponding 'binding' term should be used in combination with a transcription regulator activity child.	GO:0001095	krc	2010-10-28T02:25:22Z		True			molecular_function											owl:Class	
GO:1901637	biolink:NamedThing	obsolete positive regulation of maintenance of presynaptic active zone structure	OBSOLETE. Any process that activates or increases the frequency, rate or extent of maintenance of presynaptic active zone structure.	tmpzr1t_l9r_go_relaxed.owl	activation of maintenance of presynaptic active zone structure|upregulation of maintenance of presynaptic active zone structure|up regulation of maintenance of presynaptic active zone structure|up-regulation of maintenance of presynaptic active zone structure|positive regulation of maintenance of presynaptic active zone structure					This term was obsoleted at the TermGenie Gatekeeper stage.		ans	2012-11-15T14:17:16Z		True			biological_process											owl:Class	
GO:0008161	biolink:NamedThing	obsolete carbamate resistance	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	carbamate resistance			GO:0046681		This term was made obsolete because 'resistance' implies a phenotype rather than a biological process.					True			biological_process											owl:Class	
GO:1900545	biolink:NamedThing	obsolete regulation of phenotypic switching by regulation of transcription from RNA polymerase II promoter	OBSOLETE. A regulation of transcription from RNA polymerase II promoter that results in regulation of phenotypic switching.	tmpzr1t_l9r_go_relaxed.owl	regulation of phenotypic dimorphism by regulation of transcription from RNA polymerase II promoter					This term was obsoleted because it represents a GO-CAM model.		di	2012-05-14T11:28:41Z		True			biological_process											owl:Class	
GO:0075233	biolink:NamedThing	obsolete negative regulation of spore movement on or near host	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of spore movement on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it represented both a process and a location.					True			biological_process											owl:Class	
GO:0009475	biolink:NamedThing	obsolete high-molecular-weight cytochrome c (hexadecaheme)	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	high-molecular-weight cytochrome c (hexadecaheme)					This term was made obsolete because it represents a gene product.	GO:0009055				True			molecular_function											owl:Class	
GO:0015393	biolink:NamedThing	obsolete uracil/uridine permease activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	uracil/uridine permease activity					This term was made obsolete because it represents a multifunctional gene product.	GO:0015210|GO:0022857|GO:0015213				True			molecular_function											owl:Class	
GO:0075173	biolink:NamedThing	obsolete negative regulation of MAP kinase-mediated signal transduction in response to host	OBSOLETE. Any process in which the symbiont organism stops, prevents, or reduces the frequency, rate or extent of its symbiont MAP kinase-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of symbiont MAP kinase-mediated signal transduction in response to host					This term was obsoleted because there is no evidence that this process exists.					True			biological_process											owl:Class	
GO:0052498	biolink:NamedThing	obsolete pathogen-associated molecular pattern dependent induction by organism of symbiont innate immunity	OBSOLETE. This term was not defined before being made obsolete.	tmpzr1t_l9r_go_relaxed.owl	PAMP dependent activation of symbiont innate immunity|pathogen-associated molecular pattern dependent induction by organism of symbiont innate immunity|MAMP dependent activation of symbiont innate immunity|MAMP dependent induction of symbiont innate immunity|general elicitor-dependent induction of symbiont innate immunity|pathogen-associated molecular pattern dependent activation by organism of symbiont innate immunity|PAMP dependent induction of symbiont innate immunity|general elicitor-dependent activation of symbiont innate immunity					This term was made obsolete because it does not represent a real biological process.					True			biological_process											owl:Class	
GO:0006619	biolink:NamedThing	obsolete SRP-independent cotranslational protein-membrane targeting	OBSOLETE. The targeting of proteins to a membrane that occurs during translation and is independent of SRP and signal recognition.	tmpzr1t_l9r_go_relaxed.owl	SRP-independent cotranslational membrane targeting|SRP-independent cotranslational protein-membrane targeting|ER translocation					This term was made obsolete because there is no evidence for the existence of this process.					True			biological_process											owl:Class	
GO:1905567	biolink:NamedThing	obsolete positive regulation of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport	OBSOLETE. Any process that activates or increases the frequency, rate or extent of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of receptor-mediated endocytosis of LDL|activation of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport|upregulation of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport|up-regulation of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport|up-regulation of receptor-mediated endocytosis of LDL|activation of receptor-mediated endocytosis of LDL|up-regulation of receptor-mediated endocytosis of low-density lipoprotein involved in cholesterol transport|positive regulation of receptor-mediated endocytosis of low-density lipoprotein involved in cholesterol transport|up regulation of receptor-mediated endocytosis of low-density lipoprotein involved in cholesterol transport|up regulation of receptor-mediated endocytosis of LDL|upregulation of receptor-mediated endocytosis of LDL|up regulation of receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport|upregulation of receptor-mediated endocytosis of low-density lipoprotein involved in cholesterol transport|activation of receptor-mediated endocytosis of low-density lipoprotein involved in cholesterol transport					This term was obsoleted at the TermGenie Gatekeeper stage.		nc	2016-10-18T10:58:54Z		True			biological_process											owl:Class	
GO:0052239	biolink:NamedThing	obsolete negative chemotaxis in other organism involved in symbiotic interaction	OBSOLETE. The directed movement of a motile cell or organism towards a lower concentration of a specific chemical within a second organism, where the two organisms are in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	negative chemotaxis within other organism during symbiotic interaction|negative chemotaxis in other organism during symbiotic interaction	https://github.com/geneontology/go-ontology/issues/18819				This term was obsoleted because it represents both a process and a location.					True			biological_process											owl:Class	
GO:0034726	biolink:NamedThing	obsolete DNA replication-independent nucleosome disassembly	OBSOLETE. The controlled disassembly of chromatin outside the context of DNA replication.	tmpzr1t_l9r_go_relaxed.owl	DNA replication-independent chromatin disassembly	https://github.com/geneontology/go-ontology/issues/22133				This term was obsoleted because it did not describe a different process from that described by its parent.					True			biological_process											owl:Class	
GO:0072692	biolink:NamedThing	obsolete chromatin silencing at centromere central core	OBSOLETE. Repression of transcription of DNA at the central core of a regional centromere by altering the structure of chromatin.	tmpzr1t_l9r_go_relaxed.owl	heterochromatic silencing at centromere central core|centromere central core chromatin silencing|chromatin silencing at centromeric central core|chromatin silencing at chromosome kinetochore domain					This term was made obsolete because the process does not exist.		mah	2011-09-12T03:16:41Z		True			biological_process											owl:Class	
GO:0000198	biolink:NamedThing	obsolete activation of MAPKK activity involved in cell wall organization or biogenesis	OBSOLETE. Any process that initiates the activity of the inactive enzyme MAP kinase kinase in the context of cell wall organization or biogenesis.	tmpzr1t_l9r_go_relaxed.owl	activation of MAPKK activity involved in cell wall integrity|activation of MAPKK activity involved in cell wall biogenesis|cell wall biogenesis, activation of MAPKK activity|activation of MAP kinase kinase activity during cell wall biogenesis|cell wall biogenesis, activation of MAP kinase kinase activity	https://github.com/geneontology/go-ontology/issues/20242				This term was obsoleted because it represents a GO-CAM model.					True			biological_process											owl:Class	
GO:0030831	biolink:NamedThing	obsolete positive regulation of cGMP catabolic process	OBSOLETE. Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of cGMP.	tmpzr1t_l9r_go_relaxed.owl	upregulation of cGMP catabolic process|activation of cGMP catabolic process|positive regulation of cGMP breakdown|stimulation of cGMP catabolic process|positive regulation of cGMP degradation|up regulation of cGMP catabolic process|positive regulation of cGMP catabolism|up-regulation of cGMP catabolic process					The reason for obsoletion is that this term represents the regulation of a signaling pathway, not regulation of metabolism.					True			biological_process											owl:Class	
GO:0034419	biolink:NamedThing	obsolete L-2-hydroxyglutarate oxidase activity	OBSOLETE. Catalysis of the reaction: L-2-hydroxyglutarate + O2 = 2-oxoglutarate + hydrogen peroxide.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/21950				This term was obsoleted because this activity is not believed to exist.	GO:0140696				True			molecular_function											owl:Class	
GO:0005070	biolink:NamedThing	obsolete SH3/SH2 adaptor activity	OBSOLETE. Interacting selectively and non-covalently and simultaneously with one or more signal transduction molecules, usually acting as a scaffold to bring these molecules into close proximity either using their own SH2/SH3 domains (e.g. Grb2) or those of their target molecules (e.g. SAM68).	tmpzr1t_l9r_go_relaxed.owl	SH3/SH2 adaptor protein activity					This term was obsoleted because molecular adaptors should be represented by the type of molecules they serve to adapt, and not by their domains.					True			molecular_function											owl:Class	
RO:0002332	biolink:NamedThing	regulates levels of		tmpzr1t_l9r_go_relaxed.owl					RO:0002332									external									regulates_levels_of			
GO:0100061	biolink:NamedThing	obsolete negative regulation of SREBP signaling pathway by transcription factor catabolic process	OBSOLETE. Any transcription factor catabolic process process that negatively regulates SREBP signaling pathway.	tmpzr1t_l9r_go_relaxed.owl						The reason for obsoletion is that this term should be represented by a GO-CAM model.		cjm	2015-04-02T04:13:19Z		True			biological_process											owl:Class	
RO:0000053	biolink:NamedThing	bearer of		tmpzr1t_l9r_go_relaxed.owl					RO:0000053									external									bearer_of			
GO:0016944	biolink:NamedThing	obsolete RNA polymerase II transcription elongation factor activity	OBSOLETE. Any activity that modulates the rate of transcription elongation, the addition of ribonucleotides to an RNA molecule catalyzed by RNA polymerase II following transcription initiation.	tmpzr1t_l9r_go_relaxed.owl	RNA polymerase II transcription elongation factor activity|Pol II transcription elongation factor activity					This term was obsoleted because it is essentially identical to a Process term (specifically the Biological Process term which has been selected as a term to consider for reannotation), i.e. it is defined only in terms of the process it acts in and it does NOT convey any information about the molecular nature of the function or whether the function is based on binding DNA, on interacting with other proteins, or some other mechanism. To transfer all annotations without review, the BP term indicated is considered to be equivalent and thus the only appropriate destination for all annotations. To reannotate to a MF term, you will probably need to revisit the original literature or other primary data because this "MF" term was not defined in terms of mechanism of action and there are multiple possibilities in the revised MF structure. In reannotation, please also consider descendent terms of the suggested MF terms as a more specific term may be more appropriate than the MF terms indicated. Please be aware that you may wish to request a new term if the mechanism of action of this gene product is not yet represented or if you are annotating for an RNAP different than one for which there is a specific suggested term. Also note that if there is no information about how the gene product acts, it may be appropriate to annotate to the root term for molecular_function.	GO:0006368				True			molecular_function											owl:Class	
GO:0052215	biolink:NamedThing	obsolete energy taxis in environment of other organism involved in symbiotic interaction	OBSOLETE. The directed movement of a motile cell or organism in the environment of a second organism in response to physical parameters involved in energy generation, such as light, oxygen, and oxidizable substrates, where the two organisms are in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	energy taxis in environment of other organism during symbiotic interaction|energy taxis in response to environment of other organism					This term was obsoleted because it represents both a process and a location.					True			biological_process											owl:Class	
GO:0015259	biolink:NamedThing	obsolete glutamate channel activity	OBSOLETE. This term was not defined before being made obsolete.	tmpzr1t_l9r_go_relaxed.owl	glutamate channel activity					This term was made obsolete because this solute is transported by an active transporter rather than a channel.					True			molecular_function											owl:Class	
GO:0043848	biolink:NamedThing	obsolete excinuclease cho activity	OBSOLETE. Catalysis of the incision of damaged DNA on the 3' side of a lesion, typically at the ninth phosphodiester bond 3' of the damage.	tmpzr1t_l9r_go_relaxed.owl	uvrc homolog protein|cho|endonuclease cho					This term was obsoleted because it represented a gene product.					True			molecular_function											owl:Class	
GO:0015449	biolink:NamedThing	obsolete type IV protein (DNA-protein) secretor activity	OBSOLETE. This term was not defined before being made obsolete.	tmpzr1t_l9r_go_relaxed.owl	type IV protein (DNA-protein) secretor activity					This term was made obsolete because it does not accurately reflect the function of the proteins involved.					True			molecular_function											owl:Class	
GO:0044135	biolink:NamedThing	obsolete growth of symbiont on or near host phyllosphere	OBSOLETE. The increase in size or mass of symbiont occurring on or near its host phyllosphere. The host phyllosphere is defined as total above-ground surfaces of a plant as a habitat for symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/18786						jl	2009-08-04T04:11:23Z		True			biological_process											owl:Class	
GO:1905863	biolink:NamedThing	obsolete invadopodium organization	OBSOLETE. A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an invadopodium.	tmpzr1t_l9r_go_relaxed.owl						This term was made obsolete because an invadopodium is an abnormal structure found in cancerous or transformed cells that is out of scope of GO.		sl	2017-01-25T22:54:14Z		True			biological_process											owl:Class	
GO:0005016	biolink:NamedThing	obsolete neurotrophin TRKC receptor activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	neurotrophin TRKC receptor activity					This term was made obsolete because it represents a gene product.	GO:0007165|GO:0043121|GO:0004714				True			molecular_function											owl:Class	
GO:0090147	biolink:NamedThing	obsolete regulation of establishment of mitochondrion localization involved in mitochondrial fission	OBSOLETE. Any process that modulates the frequency, rate or extent of the directed movement of mitochondria to the correct region of the cell that contributes to the process of mitochondrial fission.	tmpzr1t_l9r_go_relaxed.owl	regulation of mitochondrial localization involved in mitochondrial fission|regulation of establishment of mitochondrion localisation involved in mitochondrial fission	https://github.com/geneontology/go-ontology/issues/18417				This term was obsoleted because it represented a phenotype.	GO:0000266|GO:0000002	tb	2009-12-08T03:01:01Z		True			biological_process											owl:Class	
GO:0004247	biolink:NamedThing	obsolete saccharolysin activity	OBSOLETE. Catalysis of the cleavage of Pro-Phe and Ala-Ala bonds.	tmpzr1t_l9r_go_relaxed.owl	saccharomyces cerevisiae proteinase yscD|oligopeptidase yscD activity|yeast cysteine proteinase D activity|proteinase yscD activity|saccharolysin activity			GO:0004222		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0030400	biolink:NamedThing	obsolete protease substrate recruitment factor activity	OBSOLETE. A recruiting factor or adaptor molecule associated with the proteasome that activates degradation of specific proteasomal substrates and links them to the degradation machinery; it is not involved in ubiquitination; does not possess proteolytic activity.	tmpzr1t_l9r_go_relaxed.owl	protease substrate recruitment factor activity					This term was made obsolete because it represents a gene product.	GO:0030674				True			molecular_function											owl:Class	
GO:0007245	biolink:NamedThing	obsolete activation of MAPKKK (mating sensu Saccharomyces)	OBSOLETE. Upregulation of MAPKKK activity in the context of transduction of mating pheromone signal, as described for Saccharomyces.	tmpzr1t_l9r_go_relaxed.owl	activation of MAPKKK (mating sensu Saccharomyces)			GO:0000750		This term was made obsolete because it is a gene product specific term.					True			biological_process											owl:Class	
GO:0000219	biolink:NamedThing	obsolete vacuolar hydrogen-transporting ATPase	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	V-ATPase|vacuolar hydrogen-transporting ATPase					This term was made obsolete because more specific terms were created.	GO:0016469				True			cellular_component											owl:Class	
GO:0030458	biolink:NamedThing	obsolete activation of MAPKKK (mating sensu Fungi)	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	activation of MAPKKK (mating sensu Fungi)			GO:0000750		This term was made obsolete because it is a gene product specific term.					True			biological_process											owl:Class	
GO:0075081	biolink:NamedThing	obsolete modulation by host of symbiont transmembrane receptor-mediated signal transduction	OBSOLETE. Any process in which the host organism modulates the frequency, rate or extent of transmembrane receptor-mediated signal transduction in the symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl						The reason for obsoletion is that there is no evidence that the host can modulate or regulate a symbiont's signal transduction pathway.					True			biological_process											owl:Class	
GO:0052351	biolink:NamedThing	obsolete induction by organism of systemic acquired resistance in symbiont	OBSOLETE. Any process in which an organism activates systemic acquired resistance in the symbiont organism; systemic acquired resistance is a salicylic acid-mediated response that confers broad spectrum systemic resistance. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	activation by organism of systemic acquired resistance in symbiont|induction by organism of systemic acquired resistance in symbiont|induction by organism of SAR in symbiont|activation by organism of SAR in symbiont					This term was made obsolete because it does not represent a real biological process.					True			biological_process											owl:Class	
GO:1902878	biolink:NamedThing	obsolete regulation of BMP signaling pathway involved in spinal cord association neuron specification	OBSOLETE. Any process that modulates the frequency, rate or extent of BMP signaling pathway involved in spinal cord association neuron specification.	tmpzr1t_l9r_go_relaxed.owl	regulation of BMP signalling pathway involved in spinal cord association neuron specification|regulation of bone morphogenetic protein signaling pathway involved in spinal cord association neuron specification|regulation of bone morphogenetic protein signalling pathway involved in spinal cord association neuron specification					The reason for obsoletion is that this term represents a GO-CAM model.		mr	2014-04-03T15:25:32Z		True			biological_process											owl:Class	
GO:0006755	biolink:NamedThing	obsolete carbamoyl phosphate-ADP transphosphorylation	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	carbamoyl phosphate-ADP transphosphorylation					This term was made obsolete because, according to PUMA2, this "pathway" is a single reaction, corresponding to 'carbamate kinase activity ; GO:0008804' (EC:2.7.2.2).					True			biological_process											owl:Class	
GO:0070215	biolink:NamedThing	obsolete MDM2 binding	OBSOLETE. Binding to an isoform of the MDM2 protein, a negative regulator of p53.	tmpzr1t_l9r_go_relaxed.owl	MDM2 binding			GO:0097371		This term was made obsolete because it represents binding to an individual protein.					True			molecular_function											owl:Class	
GO:0050991	biolink:NamedThing	obsolete enzyme active site formation via O-sulfo-L-threonine	OBSOLETE. The transient sulfation of peptidyl-threonine to form O-sulfo-L-threonine.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/15594			RESID:AA0362	This term was obsoleted because it was created by error: O-sulfo-L-threonine is a post-translational modification, see PMID:14752058.					True			biological_process											owl:Class	
GO:0052218	biolink:NamedThing	obsolete positive energy taxis in environment of other organism involved in symbiotic interaction	OBSOLETE. The directed movement of a motile cell or organism on, within or near a second organism towards a higher level of a physical stimulus involved in energy generation, such as light, oxygen, and oxidizable substrates, where the two organisms are in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	positive energy taxis in response to environment of other organism|positive energy taxis in environment of other organism during symbiotic interaction	https://github.com/geneontology/go-ontology/issues/18819				This term was obsoleted because it represents both a process and a location.					True			biological_process											owl:Class	
GO:0030406	biolink:NamedThing	obsolete matrix metalloproteinase 25 activity	OBSOLETE. Was not defined before being made obsolete.	tmpzr1t_l9r_go_relaxed.owl	matrix metalloproteinase 25 activity|MMP-25|MT6-MMP			GO:0004222		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0052474	biolink:NamedThing	obsolete negative regulation by organism of symbiont T-cell mediated immune response	OBSOLETE. Any process by which an organism stops, prevents, or reduces the frequency, rate or extent of the T-cell mediated immune response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	negative regulation by organism of symbiont T-cell mediated immune response					This term was made obsolete because it does not represent a real biological process.					True			biological_process											owl:Class	
GO:0106200	biolink:NamedThing	obsolete translocase activity acting on amio acids and peptides linked to the hydrolysis of a nucleoside triphosphate	OBSOLETE. Catalysis of the translocation of amino acids and peptides linked to the hydrolysis of a nucleoside triphosphate.	tmpzr1t_l9r_go_relaxed.owl					EC:7.4.2.-	This term was made obsolete because the concept of using the non-4 digit EC classes as parent terms for the transporter banch of the onotolgy was consided confusing.		hjd	2019-05-08T18:25:56Z		True			molecular_function											owl:Class	
GO:0004208	biolink:NamedThing	obsolete caspase-3 activity	OBSOLETE. Catalysis of the cleavage at the terminal bond of the motif: Asp-Xaa-Xaa-Asp-Xaa. Enzymes with this function are members of the peptidase family C14 and they appear to function in the inactivation of proteins involved in cellular repair and homeostasis during the effector stage of apoptosis.	tmpzr1t_l9r_go_relaxed.owl	caspase-3 activity			GO:0004197		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0005908	biolink:NamedThing	obsolete HA2 clathrin adaptor	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	HA2 clathrin adaptor|AP2					This term was made obsolete as part of a general reorganization of vesicle and vesicle coat terms; its position in the ontology was erroneous.	GO:0030122				True			cellular_component											owl:Class	
GO:0001615	biolink:NamedThing	obsolete thyrotropin releasing hormone and secretagogue-like receptors activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	thyrotropin releasing hormone and secretagogue-like receptors activity					This term was made obsolete because it represents a gene product, was not defined, and is named based on protein features.					True			molecular_function											owl:Class	
GO:0034339	biolink:NamedThing	obsolete regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor	OBSOLETE. Any process in which a ligand-bound hormone receptor acts in the nucleus to modulate the frequency, rate or extent of transcription from an RNA polymerase II promoter.	tmpzr1t_l9r_go_relaxed.owl	regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor					This term was made obsolete because it is unclear whether the term represents the action of the receptor or the entire process of transcription regulation. The term 'nuclear hormone receptor' is also misleading since many of these receptors reside in the cytoplasm until they are bound by a ligand.	GO:0006357|GO:0030374|GO:0030522|GO:0004879				True			biological_process											owl:Class	
GO:0001689	biolink:NamedThing	obsolete cytoplasmic dynein intermediate light chain	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	cytoplasmic dynein intermediate light chain			GO:0005868		This term was made obsolete because it represents a single gene product and not a complex.					True			cellular_component											owl:Class	
GO:1901643	biolink:NamedThing	obsolete regulation of tRNA methylation in response to nitrogen starvation	OBSOLETE. Any process that modulates the frequency, rate or extent of tRNA methylation in response to nitrogen starvation.	tmpzr1t_l9r_go_relaxed.owl								al	2012-11-16T14:44:08Z		True			biological_process											owl:Class	
GO:0006128	biolink:NamedThing	obsolete oxidized glutathione reduction	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	oxidized glutathione reduction					This term was made obsolete because the term string represents a molecular function and not a biological pathway.	GO:0004362|GO:0022900|GO:0006749				True			biological_process											owl:Class	
GO:1990842	biolink:NamedThing	obsolete response to prenatal stress	OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis in the embryo or fetus during pregnancy.	tmpzr1t_l9r_go_relaxed.owl	response to PNS					This term was obsoleted at the TermGenie Gatekeeper stage.		sl	2015-08-31T15:15:29Z		True			biological_process											owl:Class	
OIO:hasSynonymType	biolink:NamedThing	has_synonym_type		tmpzr1t_l9r_go_relaxed.owl																									owl:AnnotationProperty	
GO:0015289	biolink:NamedThing	obsolete pore-forming toxin activity	OBSOLETE. Catalysis of the transport of electrolytes and other small molecules across a cell membrane. They are synthesized by one cell and secreted for insertion into the membrane of another cell where they form transmembrane pores. They may exert their toxic effects by allowing the free flow of electrolytes and other small molecules across the membrane, or they may allow entry into the target cell cytoplasm of a toxin protein that ultimately kills the cell.	tmpzr1t_l9r_go_relaxed.owl	pore-forming toxin activity					This term was made obsolete because it represents a class of gene products.	GO:0005198|GO:0046930|GO:0046931|GO:0090729				True			molecular_function											owl:Class	
GO:0004442	biolink:NamedThing	obsolete inositol-1,4,-bisphosphate 3-phosphatase	OBSOLETE. Catalysis of the reaction: D-myo-inositol 1,3-bisphosphate + H2O = D-myo-inositol 1-monophosphate + phosphate.	tmpzr1t_l9r_go_relaxed.owl	inositol-1,4,-bisphosphate 3-phosphatase						GO:0004438				True			molecular_function											owl:Class	
GO:0001557	biolink:NamedThing	obsolete metabolic process resulting in cell growth	OBSOLETE. The chemical reactions that occur in living organisms that result in an increase in the mass (size) of a cell.	tmpzr1t_l9r_go_relaxed.owl	metabolic process resulting in cell growth					This term was made obsolete as part of the metabolism rearrangements, because it is redundant with other terms.	GO:0008152|GO:0016049				True			biological_process											owl:Class	
GO:0045310	biolink:NamedThing	obsolete phosphoserine/phosphothreonine binding	OBSOLETE. Interacting selectively with a phosphorylated serine or threonine residue within a protein.	tmpzr1t_l9r_go_relaxed.owl	phosphoserine/phosphothreonine binding					This term was made obsolete because it represents two functions.	GO:0050816|GO:0050815				True			molecular_function											owl:Class	
GO:0010682	biolink:NamedThing	obsolete cinnamic acid biosynthetic process involved in flavonoid metabolism	OBSOLETE. The chemical reactions and pathways resulting in the formation of cinnamic acid, 3-phenyl-2-propenoic acid, which is then utilized in the metabolism of flavonoids.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/18200				This term was obsoleted because it does not represent a specific pathway.					True			biological_process											owl:Class	
GO:0015521	biolink:NamedThing	obsolete bicyclomycin/sulfathiazole:hydrogen antiporter activity	OBSOLETE. Catalysis of the reaction: (bicyclomycin or sulfathiazole)(in) + H+(out) = (bicyclomycin or sulfathiazole)(out) + H+(in).	tmpzr1t_l9r_go_relaxed.owl	bicyclomycin/sulfathiazole:hydrogen antiporter activity|bicyclomycin/sulphathiazole:hydrogen antiporter activity|bicyclomycin/sulfathiazole:proton antiporter activity					This term was made obsolete because it represents a multifunctional gene product.	GO:0015545|GO:0045119|GO:0015546				True			molecular_function											owl:Class	
GO:0045857	biolink:NamedThing	obsolete negative regulation of molecular function, epigenetic	OBSOLETE. Any heritable epigenetic process that stops, prevents, or reduces the frequency, rate or extent of protein function by self-perpetuating conformational conversions of normal proteins in healthy cells. This is distinct from, though mechanistically analogous to, disease states associated with prion propagation and amyloidogenesis. A single protein, if it carries a glutamine/asparagine-rich ('prion') domain, can sometimes stably exist in at least two distinct physical states, each associated with a different phenotype; propagation of one of these traits is achieved by a self-perpetuating change in the protein from one form to the other, mediated by conformational changes in the glutamine/asparagine-rich domain. Prion domains are both modular and transferable to other proteins, on which they can confer a heritable epigenetic alteration of function; existing bioinformatics data indicate that they are rare in non-eukarya, but common in eukarya.	tmpzr1t_l9r_go_relaxed.owl	down regulation of protein activity, epigenetic|down-regulation of protein activity, epigenetic|inhibition of protein activity, epigenetic|downregulation of protein activity, epigenetic|negative regulation of protein activity, epigenetic	https://github.com/geneontology/go-ontology/issues/22203				This term was obsoleted because it is not an active process.					True			biological_process											owl:Class	
GO:0006324	biolink:NamedThing	obsolete S phase-specific histone modification	OBSOLETE. The covalent alteration of one or more amino acid residues within a histone protein that takes place during, and results in a modification pattern characteristic of, S phase of the cell cycle.	tmpzr1t_l9r_go_relaxed.owl	S phase-specific histone modification|S-phase-specific histone modification					This term was made obsolete because histone modification already exists and the phase specificity is better captured as an annotation extension.	GO:0016570				True			biological_process											owl:Class	
GO:0035960	biolink:NamedThing	obsolete regulation of ergosterol biosynthetic process by regulation of transcription from RNA polymerase II promoter	OBSOLETE. Any process that modulates the frequency, rate or extent of ergosterol biosynthetic process by modulating the frequency, rate or extent of transcription from an RNA polymerase II promoter.	tmpzr1t_l9r_go_relaxed.owl	regulation of ergosterol anabolism by regulation of transcription from RNA polymerase II promoter|regulation of ergosterol formation by regulation of transcription from RNA polymerase II promoter|regulation of ergosterol synthesis by regulation of transcription from Pol II promoter|regulation of ergosterol anabolism by regulation of transcription from Pol II promoter|regulation of ergosterol formation by regulation of transcription from Pol II promoter|regulation of ergosterol biosynthetic process by regulation of transcription from Pol II promoter|regulation of ergosterol biosynthesis by regulation of transcription from RNA polymerase II promoter|regulation of ergosterol biosynthesis by regulation of transcription from Pol II promoter|regulation of ergosterol synthesis by regulation of transcription from RNA polymerase II promoter					This term was obsoleted because it represents a GO-CAM model.		bf			True			biological_process											owl:Class	
GO:1901037	biolink:NamedThing	obsolete regulation of transcription from RNA polymerase II promoter during M/G1 transition of mitotic cell cycle	OBSOLETE. Any process that regulates transcription such that the target genes are transcribed during the M/G1 transition of the mitotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl	regulation of transcription from Pol II promoter during M/G1 transition of mitotic cell cycle|global transcription regulation from Pol II promoter during M/G1 transition of mitotic cell cycle|regulation of transcription during M/G1 transition of mitotic cell cycle|regulation of transcription from RNA polymerase II promoter involved in M/G1 transition of mitotic cell cycle|regulation of gene-specific transcription from RNA polymerase II promoter during M/G1 transition of mitotic cell cycle|regulation of global transcription from Pol II promoter during M/G1 transition of mitotic cell cycle|regulation of transcription from RNA polymerase II promoter during M/G1 transition of mitotic cell cycle					This term was made obsolete because it does not refer to a real biological process.	GO:0006357	pr	2012-06-21T10:09:51Z		True			biological_process											owl:Class	
GO:1904788	biolink:NamedThing	obsolete positive regulation of induction of conjugation with cellular fusion by regulation of transcription from RNA polymerase II promoter	OBSOLETE. A regulation of transcription from RNA polymerase II promoter that results in positive regulation of induction of conjugation with cellular fusion.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of induction of conjugation with cellular fusion by regulation of transcription from RNA polymerase II promoter, global|positive regulation of induction of conjugation with cellular fusion by regulation of global transcription from Pol II promoter|positive regulation of induction of conjugation with cellular fusion by regulation of transcription from Pol II promoter|positive regulation of induction of conjugation with cellular fusion by global transcription regulation from Pol II promoter|positive regulation of induction of conjugation with cellular fusion by regulation of gene-specific transcription from RNA polymerase II promoter					This term was obsoleted because it represents a GO-CAM model.		tb	2015-11-04T21:17:08Z		True			biological_process											owl:Class	
GO:0000060	biolink:NamedThing	obsolete protein import into nucleus, translocation	OBSOLETE. A protein transport process that contributes to protein import into the nucleus, and that results in the vectorial transfer of a cargo-carrier protein complex through the nuclear pore complex from the cytoplasmic side to the nucleoplasmic side of the nuclear envelope.	tmpzr1t_l9r_go_relaxed.owl	protein-nucleus import, translocation|protein import into cell nucleus, translocation|protein translocation during protein import into nucleus|protein transport from cytoplasm to nucleus, translocation|protein translocation during protein transport from cytoplasm to nucleus|protein translocation during protein-nucleus import					This term has been obsoleted because it represents a substep of the parent (GO:0006606 protein import into nucleus), has been incorrectly used.					True			biological_process											owl:Class	
produced_by	biolink:NamedThing	produced by		tmpzr1t_l9r_go_relaxed.owl					RO:0003001									external									produced_by			
GO:0030822	biolink:NamedThing	obsolete positive regulation of cAMP catabolic process	OBSOLETE. Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate).	tmpzr1t_l9r_go_relaxed.owl	positive regulation of cAMP breakdown|up regulation of cAMP catabolic process|positive regulation of 3',5'-cAMP catabolism|activation of cAMP catabolic process|positive regulation of adenosine 3',5'-cyclophosphate catabolism|positive regulation of cyclic AMP catabolic process|positive regulation of cAMP catabolism|stimulation of cAMP catabolic process|positive regulation of 3',5'-cAMP catabolic process|positive regulation of cAMP degradation|positive regulation of adenosine 3',5'-cyclophosphate catabolic process|upregulation of cAMP catabolic process|positive regulation of cyclic AMP catabolism|positive regulation of 3',5' cAMP catabolic process|positive regulation of 3',5' cAMP catabolism|up-regulation of cAMP catabolic process					The reason for obsoletion is that this term represents the regulation of a signaling pathway, not regulation of metabolism.	GO:0071878				True			biological_process											owl:Class	
GO:1905525	biolink:NamedThing	obsolete regulation of ferrichrome biosynthetic process by negative regulation of transcription from RNA polymerase II promoter in response to iron	OBSOLETE. A negative regulation of transcription from RNA polymerase II promoter in response to iron that results in regulation of ferrichrome biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	regulation of ferrichrome biosynthetic process, peptide modification by negative regulation of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome anabolism by inhibition of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome biosynthetic process by downregulation of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome biosynthesis by negative regulation of transcription from Pol II promoter in response to iron|regulation of ferrichrome formation by inhibition of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome formation by down-regulation of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome biosynthetic process, peptide modification by inhibition of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome anabolism by negative regulation of transcription from Pol II promoter in response to iron|regulation of ferrichrome synthesis by negative regulation of transcription from Pol II promoter in response to iron|regulation of ferrichrome formation by down regulation of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome formation by negative regulation of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome anabolism by downregulation of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome anabolism by down regulation of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome biosynthesis by down-regulation of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome synthesis by down regulation of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome biosynthetic process, peptide modification by down regulation of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome biosynthetic process, peptide formation by negative regulation of transcription from Pol II promoter in response to iron|regulation of ferrichrome biosynthetic process, peptide formation by negative regulation of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome biosynthetic process, peptide modification by negative regulation of transcription from Pol II promoter in response to iron|regulation of ferrichrome biosynthetic process, peptide formation by down regulation of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome biosynthetic process, peptide modification by down-regulation of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome biosynthesis by downregulation of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome synthesis by down-regulation of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome synthesis by inhibition of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome biosynthetic process, peptide formation by inhibition of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome anabolism by down-regulation of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome biosynthesis by negative regulation of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome biosynthetic process by down-regulation of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome formation by negative regulation of transcription from Pol II promoter in response to iron|regulation of ferrichrome synthesis by downregulation of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome biosynthesis by inhibition of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome biosynthetic process by down regulation of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome formation by downregulation of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome biosynthetic process, peptide formation by down-regulation of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome biosynthetic process by inhibition of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome biosynthetic process, peptide modification by downregulation of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome anabolism by negative regulation of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome biosynthetic process by negative regulation of transcription from Pol II promoter in response to iron|regulation of ferrichrome biosynthesis by down regulation of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome synthesis by negative regulation of transcription from RNA polymerase II promoter in response to iron|regulation of ferrichrome biosynthetic process, peptide formation by downregulation of transcription from RNA polymerase II promoter in response to iron					This term was made obsolete because it was added in error.		al	2016-10-04T15:46:03Z		True			biological_process											owl:Class	
GO:0075024	biolink:NamedThing	obsolete phospholipase C-mediated activation of appressorium formation	OBSOLETE. Any process that modulates the frequency, rate or extent of symbiont phospholipase C-mediated signal transduction during appressorium formation on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it represents a GO-CAM model.					True			biological_process											owl:Class	
GO:0019089	biolink:NamedThing	obsolete transmission of virus	OBSOLETE. The transfer of virions in order to create new infection.	tmpzr1t_l9r_go_relaxed.owl	viral transmission					This term was obsoleted because it did not represent a specific process, but represented the life cycle of a virus.					True			biological_process											owl:Class	
GO:0005792	biolink:NamedThing	obsolete microsome	OBSOLETE. Any of the small, heterogeneous, artifactual, vesicular particles, 50-150 nm in diameter, that are formed when some eukaryotic cells are homogenized and that sediment on centrifugation at 100000 g.	tmpzr1t_l9r_go_relaxed.owl	microsome|microsomal membrane				Wikipedia:Microsome	This term was made obsolete because it refers to a cell fractionation experimental result and not a bona fide cellular component.	GO:0043231				True			cellular_component											owl:Class	
GO:0003001	biolink:NamedThing	obsolete generation of a signal involved in cell-cell signaling	OBSOLETE. The cellular process that creates a physical entity or change in state, i.e. a signal, that originates in one cell and is used to transfer information to another cell. This process begins with the initial formation of the signal and ends with the mature form and placement of the signal.	tmpzr1t_l9r_go_relaxed.owl	formation of a signal|generation of a signal involved in cell-cell signaling|signal generation|generation of a signal involved in cell-cell signalling					This term was made obsolete because biosynthesis of a signal occurs before the start of cell-cell signaling.	GO:0023061|GO:0010496|GO:0007267|GO:0031130				True			biological_process											owl:Class	
GO:0070323	biolink:NamedThing	obsolete positive regulation of translation in response to nitrogen starvation	OBSOLETE. Any process that activates or increases the frequency, rate or extent of translation as a result of a stimulus indicating deprivation of nitrogen.	tmpzr1t_l9r_go_relaxed.owl	up regulation of translation in response to nitrogen starvation|stimulation of translation in response to nitrogen starvation|up-regulation of translation in response to nitrogen starvation|activation of translation in response to nitrogen starvation|upregulation of translation in response to nitrogen starvation	https://github.com/geneontology/go-ontology/issues/19092				This term was obsoleted because it was redundant with GO:1903833 ; positive regulation of cellular response to amino acid starvation.	GO:1903833				True			biological_process											owl:Class	
GO:0030415	biolink:NamedThing	obsolete carboxypeptidase A inhibitor activity	OBSOLETE. Stops, prevents or reduces the activity of the enzyme carboxypeptidase A.	tmpzr1t_l9r_go_relaxed.owl	carboxypeptidase A inhibitor activity			GO:0030414		This term was made obsolete because it represents a regulator of an obsolete molecular function.					True			molecular_function											owl:Class	
GO:1904501	biolink:NamedThing	obsolete positive regulation of chromatin-mediated maintenance of transcription	OBSOLETE. Any process that activates or increases the frequency, rate or extent of chromatin-mediated maintenance of transcription.	tmpzr1t_l9r_go_relaxed.owl	upregulation of chromatin-mediated maintenance of transcription|activation of chromatin-mediated maintenance of transcription|up regulation of chromatin-mediated maintenance of transcription|up-regulation of chromatin-mediated maintenance of transcription					This term was obsoleted because it represents a readout.		nc	2015-07-24T09:31:20Z		True			biological_process											owl:Class	
GO:0031263	biolink:NamedThing	obsolete ATPase-coupled amine transporter activity	OBSOLETE. Catalysis of the reaction: ATP + H2O + amine(out) = ADP + phosphate + amine(in).	tmpzr1t_l9r_go_relaxed.owl	amine-transporting ATPase activity|amine ABC transporter|ATP-dependent amine transporter activity	https://github.com/geneontology/go-ontology/issues/17164				This term was obsoleted because it corresponds to a wide range of substrates not necessarily transported by the same transporter. See https://en.wikipedia.org/wiki/Amine.					True			molecular_function											owl:Class	
RO:0002215	biolink:NamedThing	capable of		tmpzr1t_l9r_go_relaxed.owl					RO:0002215									external									capable_of			
GO:0046262	biolink:NamedThing	obsolete nitrotoluene biosynthetic process	OBSOLETE. The chemical reactions and pathways resulting in the formation of nitrotoluene, any methylbenzene molecule with NO2 group(s) attached.	tmpzr1t_l9r_go_relaxed.owl	nitrotoluene biosynthetic process|nitrotoluene biosynthesis|nitrotoluene formation|nitrotoluene synthesis|nitrotoluene anabolism			GO:0019326		This term was made obsolete because nitrotoluene is not synthesized by living organisms, and GO does not cover non-biological processes.					True			biological_process											owl:Class	
GO:0046023	biolink:NamedThing	obsolete regulation of transcription from RNA polymerase III promoter during mitotic cell cycle	OBSOLETE. A cell cycle process that modulates the frequency, rate or extent of transcription from an RNA polymerase III promoter that occurs during the mitotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl	mitotic regulation of transcription from Pol III promoter|regulation of transcription from Pol III promoter, mitotic|regulation of transcription from RNA polymerase III promoter during mitosis	https://github.com/geneontology/go-ontology/issues/14896				The reason for obsoletion is that 'during' should be captured using an annotation extension.	GO:0006359|GO:0044772				True			biological_process											owl:Class	
GO:0044041	biolink:NamedThing	obsolete multi-organism carbohydrate catabolic process	OBSOLETE. The chemical reactions and pathways resulting in the breakdown of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y, involving more than one organism.	tmpzr1t_l9r_go_relaxed.owl	multi-organism carbohydrate breakdown|multi-organism carbohydrate catabolism|multi-organism carbohydrate degradation	https://github.com/geneontology/go-ontology/issues/19769				This term was obsoleted because there is no evidence that this process exists.					True			biological_process											owl:Class	
GO:0005077	biolink:NamedThing	obsolete MAP-kinase anchoring activity	OBSOLETE. Binds to MAP kinase and anchors it to a particular subcellular location.	tmpzr1t_l9r_go_relaxed.owl	MAP-kinase anchor protein activity|MAP-kinase anchoring activity					This term was made obsolete because it represents a combination of process and function information.	GO:0051019|GO:0008104				True			molecular_function											owl:Class	
GO:0052396	biolink:NamedThing	obsolete induction by organism of symbiont non-apoptotic programmed cell death	OBSOLETE. Any process by which an organism activates programmed cell death in the symbiont, where programmed cell death proceeds by a non-apoptotic pathway. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	induction by organism of symbiont non-apoptotic programmed cell death|activation by organism of symbiont non-apoptotic programmed cell death					This term was made obsolete because it does not represent a real biological process.					True			biological_process											owl:Class	
GO:0005037	biolink:NamedThing	obsolete death receptor adaptor protein activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	death receptor adaptor protein activity					This term was made obsolete because it represents a gene product and not a molecular function.	GO:0005515|GO:0005123				True			molecular_function											owl:Class	
GO:0100015	biolink:NamedThing	obsolete positive regulation of inositol biosynthetic process by transcription from RNA polymerase II promoter	OBSOLETE. Any transcription from RNA polymerase II promoter process that positively regulates inositol biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it represents a GO-CAM model.		cjm	2015-04-02T04:13:19Z		True			biological_process											owl:Class	
GO:0051113	biolink:NamedThing	obsolete enzyme active site formation via 1'-(phospho-5'-adenosine)-L-histidine	OBSOLETE. The transient adenylylation of peptidyl-histidine to form 1'-(phospho-5'-adenosine)-L-histidine (otherwise known as tau-AMP-histidine, tele-AMP-histidine).	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/15594			RESID:AA0371	This term was obsoleted because it represents a reaction intermediate, not a biological process, see PMID:15182206.					True			biological_process											owl:Class	
GO:0052358	biolink:NamedThing	obsolete catabolism by host of symbiont glucan	OBSOLETE. The chemical reactions and pathways performed by an organism resulting in the breakdown of glucan molecules within the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/21396				This term was obsoleted because there is no evidence it exists.					True			biological_process											owl:Class	
GO:0016173	biolink:NamedThing	obsolete ice nucleation inhibitor activity	OBSOLETE. Inhibits the formation of ice crystals.	tmpzr1t_l9r_go_relaxed.owl	ice nucleation inhibitor activity					This term was made obsolete because it refers to a biological process.	GO:0042309|GO:0050826|GO:0050825				True			molecular_function											owl:Class	
GO:0046757	biolink:NamedThing	obsolete lytic virus budding from ER membrane	OBSOLETE. A form of viral release in which the nucleocapsid evaginates from the host endoplasmic reticulum membrane system, resulting in envelopment of the virus and cell lysis.	tmpzr1t_l9r_go_relaxed.owl	lytic viral budding from ER membrane|lytic ER membrane viral budding|lytic virus budding from ER membrane|lytic endoplasmic reticulum membrane viral budding					This term was made obsolete because it does not appear to correspond to a real biological process.					True			biological_process											owl:Class	
GO:0007256	biolink:NamedThing	obsolete activation of JNKK activity	OBSOLETE. The initiation of the activity of the inactive enzyme JUN kinase kinase (JNKK) activity. JNKKs are involved in a signaling pathway that is primarily activated by cytokines and exposure to environmental stress.	tmpzr1t_l9r_go_relaxed.owl	activation of JUN kinase kinase activity|positive regulation of JUNKK activity	https://github.com/geneontology/go-ontology/issues/21307				This term was obsoleted because it represents a molecular function.	GO:0046328|GO:0043539				True			biological_process											owl:Class	
GO:0036129	biolink:NamedThing	obsolete negative regulation of transcription from RNA polymerase II promoter in response to hydrogen peroxide	OBSOLETE. Any process that decreases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a hydrogen peroxide (H2O2) stimulus.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it represents a GO-CAM model.	GO:0000122	bf	2012-03-02T10:36:39Z		True			biological_process											owl:Class	
GO:0051637	biolink:NamedThing	obsolete Gram-positive bacterial cell surface binding	OBSOLETE. Binding to a component on the surface of a Gram-positive bacterium.	tmpzr1t_l9r_go_relaxed.owl	Gram-positive bacterium binding|binding to Gram-positive bacterium|Gram-positive bacterium cell surface binding|Gram-positive bacterial cell surface binding|Gram-positive bacterial binding					This term was made obsolete because it is an unnecessary grouping term and was causing confusion.	GO:0003823|GO:0050830				True	GO:0051076		molecular_function											owl:Class	
GO:0033261	biolink:NamedThing	obsolete regulation of S phase	OBSOLETE. A cell cycle process that modulates the rate or extent of the progression through the S phase of the cell cycle.	tmpzr1t_l9r_go_relaxed.owl	regulation of S-phase|regulation of progression through S phase|regulation of S phase				MetaCyc:PWY-5043|MetaCyc:SALVPURINE2-PWY|MetaCyc:SALVADEHYPOX-PWY	This term was made obsolete because cell cycle phases are intervals and so cannot be regulated as such, rather it is the transitions between the phases that are regulated. This term was often also used to annotate genes which should have been annotated to 'regulation of DNA replication', or one of its children.	GO:0044770				True			biological_process											owl:Class	
GO:0008224	biolink:NamedThing	obsolete Gram-positive antibacterial peptide activity	OBSOLETE. Inhibits the growth of, or directly kills, Gram-positive bacterial cells.	tmpzr1t_l9r_go_relaxed.owl	Gram-positive antibacterial peptide activity					This term was made obsolete because it describes involvement in a process and not a function.	GO:0050830				True			molecular_function											owl:Class	
GO:1904499	biolink:NamedThing	obsolete regulation of chromatin-mediated maintenance of transcription	OBSOLETE. Any process that modulates the frequency, rate or extent of chromatin-mediated maintenance of transcription.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it represents a readout.		nc	2015-07-24T09:31:08Z		True			biological_process											owl:Class	
GO:0018704	biolink:NamedThing	obsolete 5-chloro-2-hydroxymuconic semialdehyde dehalogenase activity	OBSOLETE. Catalysis of the reaction: 5-chloro-2-hydroxymuconic semialdehyde + H+ + 2 e- = Cl- + 2-hydroxymuconic semialdehyde.	tmpzr1t_l9r_go_relaxed.owl	5-chloro-2-hydroxymuconic semialdehyde dehalogenase activity					This term was made obsolete because it was derived from a UM-BBD enzyme entry that has been deleted, and no other information can be found to suggest that it is a naturally occurring activity.					True			molecular_function											owl:Class	
GO:2000576	biolink:NamedThing	obsolete positive regulation of microtubule motor activity	OBSOLETE. Any process that activates or increases the frequency, rate or extent of microtubule motor activity.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of kinesin|positive regulation of axonemal motor activity|positive regulation of dynein|positive regulation of kinetochore motor activity|positive regulation of dynein ATPase activity|positive regulation of kinesin motor activity	https://github.com/geneontology/go-ontology/issues/21626				This term was obsoleted because it represents a molecular function.	GO:0140660	bf	2011-04-05T08:36:51Z		True			biological_process											owl:Class	
GO:0051804	biolink:NamedThing	obsolete positive regulation of cytolysis in other organism involved in symbiotic interaction	OBSOLETE. Any process in which an organism activates or increases the frequency, rate or extent of cytolysis by that organism of cells in a second organism, where the two organisms are in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of cytolysis of cells in other organism during symbiotic interaction|up regulation of cytolysis of cells in other organism during symbiotic interaction|stimulation of cytolysis of cells in other organism during symbiotic interaction|positive regulation of cytolysis of cells in other organism involved in symbiotic interaction|up-regulation of cytolysis of cells in other organism during symbiotic interaction|upregulation of cytolysis of cells in other organism during symbiotic interaction|activation of cytolysis of cells in other organism during symbiotic interaction					This term was obsoleted because it represents an unnecessary grouping class.					True			biological_process											owl:Class	
GO:0035569	biolink:NamedThing	obsolete N-terminal peptidyl-proline trimethylation	OBSOLETE. The trimethylation of the N-terminal proline of proteins to form the derivative N,N,N-trimethylproline.	tmpzr1t_l9r_go_relaxed.owl	N-terminal peptidyl-proline trimethylation					This term was made obsolete because N-terminal proline residues cannot be trimethylated.		bf	2010-08-06T01:55:19Z		True			biological_process											owl:Class	
GO:0023007	biolink:NamedThing	obsolete ligand binding to T cell receptor	OBSOLETE. Binding of a diffusible ligand to a T cell receptor as part of a signaling process.	tmpzr1t_l9r_go_relaxed.owl	ligand binding to T cell receptor					This term was made obsolete because it is describing a binding molecular function.	GO:0050852|GO:0042101|GO:0042608		2010-02-16T09:30:50Z		True			biological_process											owl:Class	
GO:0016821	biolink:NamedThing	obsolete hydrolase activity, acting on acid anhydrides, involved in cellular and subcellular movement	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	hydrolase activity, acting on acid anhydrides, involved in cellular and subcellular movement			GO:0016817		This term was made obsolete because it incorporates process information.					True			molecular_function											owl:Class	
GO:1900388	biolink:NamedThing	obsolete regulation of vesicle-mediated transport by regulation of transcription from RNA polymerase II promoter	OBSOLETE. A regulation of transcription from RNA polymerase II promoter that results in regulation of vesicle-mediated transport.	tmpzr1t_l9r_go_relaxed.owl	regulation of vesicle-mediated transport by regulation of transcription from RNA polymerase II promoter					This term was made obsolete because there is no evidence that vesicle-mediated transport is regulated transcriptionally.		mah	2012-04-18T03:52:29Z		True			biological_process											owl:Class	
GO:0016921	biolink:NamedThing	obsolete pyroglutamyl-peptidase II activity	OBSOLETE. Catalysis of the release of the N-terminal pyroglutamyl group from pGlu-His-Xaa tripeptides and pGlu-His-Xaa-Gly tetrapeptides.	tmpzr1t_l9r_go_relaxed.owl	thyrotropin-releasing hormone-degrading peptidase activity|thyrotropin-releasing hormone-degrading pyroglutamate aminopeptidase activity|TRH-degrading ectoenzyme activity|thyrotropin-releasing factor pyroglutamate aminopeptidase activity|TRH-specific aminopeptidase activity|pyroglutamate aminopeptidase II|TRH-DE activity|pyroglutamyl peptidase II|thyrotropin-releasing hormone degrading ectoenzyme activity|thyroliberinase activity|pyroglutamyl aminopeptidase II activity|PAP-II activity|thyroliberin-hydrolyzing pyroglutamate aminopeptidase activity|pyroglutamyl-peptidase II activity				EC:3.4.19.6|MetaCyc:3.4.19.6-RXN	This term was made obsolete because it represents a gene product.	GO:0016920|GO:0008237				True			molecular_function											owl:Class	
GO:0042801	biolink:NamedThing	obsolete polo kinase kinase activity	OBSOLETE. Catalysis of the addition of a phosphate group onto a serine or threonine residue in any member of the polo kinase class of proteins.	tmpzr1t_l9r_go_relaxed.owl						This term was made obsolete because it represents a gene product and also refers to a non-existent activity (polo kinase).					True			molecular_function											owl:Class	
GO:0006905	biolink:NamedThing	obsolete vesicle transport	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	vesicle transport					This term was made obsolete because the meaning of the term is ambiguous.	GO:0016192				True			biological_process											owl:Class	
GO:0015601	biolink:NamedThing	obsolete cystine/diaminopimelate porter activity	OBSOLETE. Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + polar amino acid(out) = ADP + phosphate + polar amino acid(in).	tmpzr1t_l9r_go_relaxed.owl	cystine/diaminopimelate porter activity					This term was made obsolete because it represents a multifunctional gene product.	GO:0015426|GO:0015184|GO:0015626				True			molecular_function											owl:Class	
GO:1903957	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0039608	biolink:NamedThing	obsolete suppression by virus of host translation initiation factor activity by induction of host protein dephosphorylation	OBSOLETE. Any process in which a virus prevents or reduces the frequency, rate or extent of activity of a host translation initiation factor by promoting dephosphorylation of a host protein.	tmpzr1t_l9r_go_relaxed.owl						The reason for obsoleting this term is that it is too specific. The exact molecular roles of the individual proteins should be captured separately.		bf	2012-07-06T10:30:57Z		True			biological_process											owl:Class	
GO:0030271	biolink:NamedThing	obsolete chymase activity	OBSOLETE. Catalysis of the preferential cleavage: Phe-Xaa > Tyr-Xaa > Trp-Xaa > Leu-Xaa.	tmpzr1t_l9r_go_relaxed.owl	skeletal muscle (SK) protease activity|mast cell serine proteinase|SK protease activity|mast cell protease I activity|skin chymotryptic proteinase|skeletal muscle protease|chymase activity			GO:0004252		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
RO:0002297	biolink:NamedThing	results in formation of		tmpzr1t_l9r_go_relaxed.owl					RO:0002297									external									results_in_formation_of			
GO:0045897	biolink:NamedThing	obsolete positive regulation of transcription during mitotic cell cycle	OBSOLETE. Any process that activates or increases the frequency, rate or extent of transcription that occurs during the mitotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of transcription during mitosis|mitotic activation of transcription|upregulation of transcription during mitosis|stimulation of transcription during mitosis|up regulation of transcription during mitosis|activation of transcription during mitosis|positive regulation of transcription, mitotic	https://github.com/geneontology/go-ontology/issues/14896				The reason for obsoletion is that 'during' should be captured using an annotation extension.	GO:0045944|GO:0044772				True			biological_process											owl:Class	
GO:0003141	biolink:NamedThing	obsolete transforming growth factor beta receptor signaling pathway involved in determination of lateral mesoderm left/right asymmetry	OBSOLETE. The series of molecular signals generated as a consequence of a transforming growth factor beta receptor binding to one of its physiological ligands that contributes to lateral mesoderm left/right asymmetry determination.	tmpzr1t_l9r_go_relaxed.owl	TGFbeta receptor signaling pathway involved in determination of lateral mesoderm left/right asymmetry|TGF-beta receptor signaling pathway involved in determination of lateral mesoderm left/right asymmetry|transforming growth factor beta receptor signalling pathway involved in determination of lateral mesoderm left/right asymmetry|TGFbeta receptor signalling pathway involved in determination of lateral mesoderm left/right asymmetry|transforming growth factor beta receptor signaling pathway involved in determination of lateral mesoderm left/right asymmetry|transforming growth factor beta receptor signaling pathway involved in lateral mesoderm left/right asymmetry determination|TGF-beta receptor signalling pathway involved in determination of lateral mesoderm left/right asymmetry			GO:1900164		This term was made obsolete because it describes involvement of the nodal signaling pathway in lateral mesoderm left/right asymmetry. Nodal proteins are members of the TGF-beta superfamily, but are distinct from TGF-beta proteins themselves. TGF-beta proteins are not currently known to regulate left/right asymmetry in the lateral mesoderm.		tb	2009-09-22T04:03:22Z		True			biological_process											owl:Class	
GO:0060868	biolink:NamedThing	obsolete regulation of vesicle-mediated transport involved in floral organ abscission by small GTPase mediated signal transduction	OBSOLETE. Any series of molecular signals in which a small monomeric GTPase relays one or more of the signals that modulates the rate or extent of floral organ abscission.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/18200				This term was obsoleted because it does not represent a specific pathway.		dph	2009-08-12T06:52:13Z		True			biological_process											owl:Class	
GO:0075072	biolink:NamedThing	obsolete autophagy of symbiont cells involved in interaction with host	OBSOLETE. The process in which symbiont cells digest parts of their own cytoplasm during interaction with its host. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	autophagy of symbiont cells during interaction with host					The reason for obsoletion is that this term did not represent any specific host/symbiont process.					True			biological_process											owl:Class	
BFO:0000063	biolink:NamedThing	precedes		tmpzr1t_l9r_go_relaxed.owl					BFO:0000063									external									precedes			
GO:0038072	biolink:NamedThing	obsolete MAP kinase kinase activity involved in conjugation with cellular fusion	OBSOLETE. Catalysis of the concomitant phosphorylation of threonine (T) and tyrosine (Y) residues in a Thr-Glu-Tyr (TEY) thiolester sequence in a MAP kinase (MAPK) substrate, as part of a MAPK signaling cascade that contributes to conjugation with cellular fusion.	tmpzr1t_l9r_go_relaxed.owl	MAPKK activity involved in conjugation with cellular fusion|MAP2K activity involved in conjugation with cellular fusion					This term has been obsoleted because it represents a GO-CAM model rather than a single GO term.		bf	2012-01-26T02:31:57Z		True			molecular_function											owl:Class	
GO:0075151	biolink:NamedThing	obsolete positive regulation of receptor-mediated signal transduction in response to host	OBSOLETE. Any process in which the symbiont organism activates, maintains or increases the frequency, rate or extent of its receptor-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of symbiont receptor-mediated signal transduction in response to host					This term was obsoleted because there is no evidence that this process exists.					True			biological_process											owl:Class	
GO:0046198	biolink:NamedThing	obsolete cresol biosynthetic process	OBSOLETE. The chemical reactions and pathways resulting in the formation of cresol, a mixture of the aromatic alcohol isoforms o-, p-, and m-cresol, which is obtained from coal tar or petroleum. The isomers are used as disinfectants, textile scouring agents, surfactants and as intermediates in the manufacture of salicylaldehyde, coumarin, and herbicides as well as being a major component of creosote.	tmpzr1t_l9r_go_relaxed.owl	cresol synthesis|cresol formation|cresol anabolism|cresol biosynthesis|cresol biosynthetic process			GO:0042212		This term was made obsolete because cresol is not synthesized by living organisms, and GO does not cover non-biological processes.					True			biological_process											owl:Class	
GO:0004276	biolink:NamedThing	obsolete furin activity	OBSOLETE. Catalysis of the release of mature proteins from their proproteins by cleavage of the terminal bond of Arg-Xaa-Yaa-Arg-Z motifs where Xaa can be any amino acid and Yaa is Arg or Lys. Releases albumin, complement component C3 and von Willebrand factor from their respective precursors.	tmpzr1t_l9r_go_relaxed.owl	furin activity|PACE|paired basic amino acid cleaving enzyme|paired basic amino acid converting enzyme|serine proteinase PACE|prohormone convertase activity|paired basic amino acid residue cleaving enzyme activity|SPC3|dibasic processing enzyme activity			GO:0004252		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0006340	biolink:NamedThing	obsolete negative regulation of transcription of homeotic gene (Polycomb group)	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of transcription of homeotic genes of the Polycomb group.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of transcription of homeotic gene (Polycomb group)					This term was made obsolete because it relates to a specific gene family rather than a process.	GO:0031507|GO:0000122|GO:0045815				True			biological_process											owl:Class	
GO:0030006	biolink:NamedThing	obsolete heavy cellular metal ion homeostasis	OBSOLETE. Regulation of the levels, transport, and metabolism of ions of a heavy metal, a metal that can form a coordination bond with a protein, as opposed to an alkali or alkaline-earth metal that can only form an ionic bond; this definition includes the following biologically relevant heavy metals: Cd, Co, Cu, Fe, Hg, Mn, Mo, Ni, V, W, Zn.	tmpzr1t_l9r_go_relaxed.owl	heavy cellular metal ion homeostasis					This term was made obsolete because 'heavy metal' is an ambiguous grouping term which has no set meaning (see Pure Appl. Chem. Vol. 74, No. 5, pp. 793-807, 2002, for more information).	GO:0006875				True			biological_process											owl:Class	
GO:0007068	biolink:NamedThing	obsolete negative regulation of transcription during mitotic cell cycle	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of transcription that occurs during the mitotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl	down regulation of transcription during mitosis|negative regulation of transcription, mitotic|mitotic repression of transcription|downregulation of transcription during mitosis|inhibition of transcription during mitosis|down-regulation of transcription during mitosis	https://github.com/geneontology/go-ontology/issues/14896				The reason for obsoletion is that 'during' should be captured using an annotation extension.	GO:0000122|GO:0044772				True			biological_process											owl:Class	
GO:0018192	biolink:NamedThing	obsolete enzyme active site formation via cysteine modification to L-cysteine persulfide	OBSOLETE. The formation of an enzyme active site via modification of peptidyl-cysteine to peptidyl-L-cysteine persulfide.	tmpzr1t_l9r_go_relaxed.owl	enzyme active site formation via L-cysteine persulphide	https://github.com/geneontology/go-ontology/issues/15594				This term was obsoleted because it represents a reaction intermediate, not a biological process, see PMID:11592406.	GO:0004792				True			biological_process											owl:Class	
GO:0005572	biolink:NamedThing	obsolete RNA polymerase II transcribed untranslated RNA	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	RNA polymerase II transcribed untranslated RNA					Note that this term was deleted from GO and was restored to the ontology in Feb 2003 to ensure that the ID is not reused.					True			cellular_component											owl:Class	
GO:0009352	biolink:NamedThing	obsolete dihydrolipoyl dehydrogenase complex	OBSOLETE. Complex that possesses dihydrolipoyl dehydrogenase activity.	tmpzr1t_l9r_go_relaxed.owl	dihydrolipoamide dehydrogenase complex|dihydrolipoyl dehydrogenase complex					This term was made obsolete because the activity dihydrolipoamide dehydrogenase is held by a single protein (Lpd1 in yeast), which is one of the components of three different complexes: 2-oxoglutarate dehydrogenase, pyruvate dehydrogenase, and branch chain amino acid dehydrogenase, so dihydrolipoamide dehydrogenase is not a complex itself.	GO:0004148|GO:0045240|GO:0045254				True			cellular_component											owl:Class	
GO:0003928	biolink:NamedThing	obsolete RAB small monomeric GTPase activity	OBSOLETE. Catalysis of the reaction: GTP + H2O = GDP + phosphate.	tmpzr1t_l9r_go_relaxed.owl	RAB small monomeric GTPase activity			GO:0003924		This term was made obsolete because it represents a gene product.	GO:0016192|GO:0016191				True			molecular_function											owl:Class	
GO:0007353	biolink:NamedThing	obsolete ventral/lateral system	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	ventral/lateral system					This term was made obsolete because it does not describe a biological process.	GO:0009880				True			biological_process											owl:Class	
GO:0000116	biolink:NamedThing	obsolete regulation of transcription involved in G2-phase of mitotic cell cycle	OBSOLETE. Any process that regulates transcription such that the target genes are transcribed as part of the G2 phase of the mitotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl	G2-specific transcription in mitotic cell cycle|regulation of transcription involved in G2-phase of mitotic cell cycle|regulation of transcription from RNA polymerase II during G2-phase of mitotic cell cycle					This term was made obsolete because it is unclear exactly what it means. It could mean either 'regulation of transcription during phase X' or 'regulation of transition between phase X and phase Y'.	GO:0006357|GO:0000117				True			biological_process											owl:Class	
GO:0001598	biolink:NamedThing	obsolete chemokine receptor-like receptor activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	chemokine receptor-like receptor activity					This term was made obsolete because it represents a gene product, was not defined, and is named based on protein features.					True			molecular_function											owl:Class	
GO:0042708	biolink:NamedThing	obsolete elastase activity	OBSOLETE. Catalysis of the hydrolysis of elastin.	tmpzr1t_l9r_go_relaxed.owl	elastase activity			GO:0004175		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0006153	biolink:NamedThing	obsolete purine nucleosidase reaction	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	purine nucleosidase reaction			GO:0008477		This term was made obsolete because it represents a molecular function.					True			biological_process											owl:Class	
GO:0098679	biolink:NamedThing	obsolete regulation of carbohydrate catabolic process by regulation of transcription from RNA polymerase II promoter	OBSOLETE. A regulation of transcription from RNA polymerase II promoter that results in regulation of carbohydrate catabloism.	tmpzr1t_l9r_go_relaxed.owl	regulation of carbohydrate catabolism by regulation of transcription from RNA polymerase II promoter					This term was obsoleted because it represents a GO-CAM model.		dos	2017-01-31T14:46:21Z		True			biological_process											owl:Class	
GO:0006628	biolink:NamedThing	obsolete mitochondrial translocation	OBSOLETE. The translocation of proteins across the mitochondrial membrane. In the presence of a translocating chain, the outer membrane import machinery (MOM complex) and the inner membrane import machinery (MIM complex) form translocation contact sites as a part of the membrane preprotein import machinery.	tmpzr1t_l9r_go_relaxed.owl	mitochondrial translocation					This term was made obsolete because its definition was equivalent to that of the biological process term 'mitochondrial matrix protein import ; GO:0030150' while the mitochondrial translocation has a broader meaning; this led to mis-annotation.	GO:0006626				True			biological_process											owl:Class	
GO:1990022	biolink:NamedThing	obsolete RNA polymerase III complex import into nucleus	OBSOLETE. The directed movement of an RNA polymerase III complex from the cytoplasm to the nucleus.	tmpzr1t_l9r_go_relaxed.owl	RNA polymerase III complex import into nucleus|RNA polymerase III complex localisation to nucleus|DNA-directed RNA polymerase III complex localization to nucleus|DNA-directed RNA polymerase III complex import into nucleus|RNA polymerase III complex localization to nucleus					The reason for obsoletion is that all proteins are imported into the nucleus via the same mechanism, so the import of individual proteins should be captured with extensions or by GO-CAM models.	GO:0006606	pr	2013-01-15T12:46:26Z		True			biological_process											owl:Class	
GO:0043746	biolink:NamedThing	obsolete N2-acetyl-L-lysine aminotransferase activity	OBSOLETE. Catalysis of the reaction: N2-acetyl-L-aminoadipate semialdehyde + L-glutamate = 2-oxoglutarate + N2-acetyl-L-lysine.	tmpzr1t_l9r_go_relaxed.owl	N-acetyl-lysine aminotransferase activity	https://github.com/geneontology/go-ontology/issues/18908				This term was obsoleted because there is no evidence that it exists.					True			molecular_function											owl:Class	
GO:0005106	biolink:NamedThing	obsolete ephrin	OBSOLETE. A class of proteins that interact with the ephrin receptors.	tmpzr1t_l9r_go_relaxed.owl	ephrin					This term was made obsolete because it refers to a class of gene products.	GO:0046875				True			molecular_function											owl:Class	
GO:0005552	biolink:NamedThing	obsolete polyubiquitin	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	polyubiquitin					This term was made obsolete because it represents a gene product and not a molecular function.	GO:0000209				True			molecular_function											owl:Class	
GO:0031937	biolink:NamedThing	obsolete positive regulation of chromatin silencing	OBSOLETE. Any process that activates or increases the frequency, rate or extent of chromatin silencing.	tmpzr1t_l9r_go_relaxed.owl	stimulation of chromatin silencing|up-regulation of chromatin silencing|up regulation of chromatin silencing|activation of chromatin silencing|upregulation of chromatin silencing|positive regulation of heterochromatic silencing	https://github.com/geneontology/go-ontology/issues/22060				This term was obsoleted because it was too vague: regulation of chromatin (gene) silencing takes place via upstream signaling pathways.					True			biological_process											owl:Class	
GO:0030067	biolink:NamedThing	obsolete respiratory chain cytochrome b6	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	respiratory chain cytochrome b6					This term was made obsolete because it represents a gene product.	GO:0009055				True			molecular_function											owl:Class	
GO:0004275	biolink:NamedThing	obsolete enteropeptidase activity	OBSOLETE. Catalysis of the selective cleavage of Lys6-Ile7 bond in trypsinogen.	tmpzr1t_l9r_go_relaxed.owl	enteropeptidase activity|enterokinase activity			GO:0004252		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:2000688	biolink:NamedThing	obsolete positive regulation of rubidium ion transmembrane transporter activity	OBSOLETE. Any process that activates or increases the frequency, rate or extent of rubidium ion transmembrane transporter activity.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of rubidium transmembrane transporter activity|positive regulation of Rb+ transmembrane transporter activity|positive regulation of rubidium cation transmembrane transporter activity					This term has been obsoleted because it represents an assay, and not a physiological process.		bf	2011-05-11T09:27:33Z		True			biological_process											owl:Class	
GO:0019765	biolink:NamedThing	obsolete low affinity Fc receptor activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	low affinity Fc receptor activity					This term was made obsolete because it is undefined and is an unnecessary grouping term.	GO:0019769|GO:0019772				True			molecular_function											owl:Class	
GO:0097032	biolink:NamedThing	obsolete mitochondrial respiratory chain complex II biogenesis	OBSOLETE. The biogenesis of a mitochondrial respiratory chain complex II, a protein complex located in the mitochondrial inner membrane that forms part of the mitochondrial respiratory chain. Includes the synthesis of constituent proteins and their aggregation, arrangement and bonding together.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/15173				The reason for obsoletion is that 'biogenesis' as related to a protein is translation, and there is no indication that the members of these complexes are synthesized in a particular way. Historically biogenesis terms were created for some processes when the level of a molecule was changed by an unknown mechanism, for instance transcription, translation, assembly etc. This is now considered too indirect for annotation.		pr	2011-04-05T02:57:33Z		True			biological_process											owl:Class	
GO:0009388	biolink:NamedThing	obsolete antisense RNA	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	antisense RNA					This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0015602	biolink:NamedThing	obsolete leucine/isoleucine/valine porter activity	OBSOLETE. Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + nonpolar amino acid(out) = ADP + phosphate + nonpolar amino acid(in).	tmpzr1t_l9r_go_relaxed.owl	leucine/isoleucine/valine porter activity					This term was made obsolete because it represents a multifunctional gene product.	GO:0015425|GO:0015188|GO:0015190|GO:0005304				True			molecular_function											owl:Class	
GO:0052387	biolink:NamedThing	obsolete induction by organism of symbiont apoptosis	OBSOLETE. Any process by which an organism activates programmed cell death in the symbiont, where programmed cell death proceeds by apoptosis. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	induction by organism of symbiont apoptotic programmed cell death|activation by organism of symbiont apoptosis|activation by organism of symbiont apoptotic programmed cell death|induction by organism of symbiont apoptosis					This term was made obsolete because it does not represent a real biological process.					True			biological_process											owl:Class	
GO:0032853	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1990129	biolink:NamedThing	obsolete pre-primosome complex involved in replication restart	OBSOLETE. A protein-DNA complex involved in replication restart after a stalled replication fork has been repaired.	tmpzr1t_l9r_go_relaxed.owl	pre-primosome complex involved in replication restart					This term was obsoleted at the TermGenie Gatekeeper stage.		bhm	2013-06-24T10:36:30Z		True			cellular_component											owl:Class	
GO:0007085	biolink:NamedThing	obsolete nuclear membrane vesicle binding to chromatin	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	nuclear membrane vesicle binding to chromatin					This term was made obsolete because it represents a molecular function.	GO:0003682				True			biological_process											owl:Class	
GO:0038040	biolink:NamedThing	obsolete cross-receptor activation within G-protein coupled receptor heterodimer	OBSOLETE. Activation of one protomer of a consequence of a G protein-coupled (GPCR) heterodimer by the associated subunit. For example, agonist occupancy in one protomer of a GPCR dimer may activate the associated promoter.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/15823				This term was obsoleted because it should be captured as a GO-CAM model.		bf	2011-11-02T04:50:22Z		True			biological_process											owl:Class	
GO:0052364	biolink:NamedThing	obsolete catabolism by host of substance in symbiont	OBSOLETE. The chemical reactions and pathways performed by an organism in its symbiont resulting in the breakdown of substances. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/21469				This term was obsoleted because it represents a molecular function.					True			biological_process											owl:Class	
GO:0052475	biolink:NamedThing	obsolete negative regulation by organism of symbiont cell-mediated immune response	OBSOLETE. Any process by which an organism stops, prevents, or reduces the frequency, rate or extent of the cell mediated immune response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	negative regulation by organism of symbiont cell-mediated immune response|negative regulation by organism of symbiont cell-based immune response					This term was made obsolete because it does not represent a real biological process.					True			biological_process											owl:Class	
GO:0007101	biolink:NamedThing	obsolete male meiosis centrosome cycle	OBSOLETE. Centrosome duplication and separation in the context of a meiotic cell cycle in a male organism.	tmpzr1t_l9r_go_relaxed.owl	centrosome cycle involved in male meiotic cell cycle					false					True			biological_process											owl:Class	
GO:0072451	biolink:NamedThing	obsolete detection of stimulus involved in G2 cell size control checkpoint	OBSOLETE. The series of events in which information about cell size is received and converted into a molecular signal, contributing to a G2/M transition size control checkpoint.	tmpzr1t_l9r_go_relaxed.owl	G2/M transition size control checkpoint sensor process|sensing involved in G2/M transition size control checkpoint|detection of stimulus involved in mitotic cell cycle G2/M transition size control checkpoint|G2/M transition size control checkpoint sensor mechanism|detection of stimulus involved in G2/M transition size control checkpoint	https://github.com/geneontology/go-ontology/issues/20976				This term was obsoleted because it corresponds to a molecular function.		mah	2010-12-09T11:14:00Z		True			biological_process											owl:Class	
GO:0052209	biolink:NamedThing	obsolete interaction with other organism via substance secreted by type IV secretion system involved in symbiotic interaction	OBSOLETE. An interaction with a second organism mediated by a substance secreted by the first organism by a type IV secretion system, where the two organisms are in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	interaction with other organism via substance secreted by type IV secretion system during symbiotic interaction					This term was obsoleted because it conflated the process in which a gene product is involved with the secretion system by which it reaches its target.					True			biological_process											owl:Class	
GO:0044664	biolink:NamedThing	obsolete reversion of cell type to default state involved in phenotypic switching	OBSOLETE. The cellular process of the reversion of cells to their original cell type, occurring as part of the process of phenotypic switching. Phenotypic switching begins with changes in cell morphology and altered gene expression patterns and ends when the morphology of a population of cells has reverted back to the default state, accompanied by altered expression patterns.	tmpzr1t_l9r_go_relaxed.owl						This term was made obsolete because it is ambiguous.		jl	2012-08-07T14:35:48Z		True			biological_process											owl:Class	
GO:0044251	biolink:NamedThing	obsolete protein catabolic process by pepsin	OBSOLETE. The chemical reactions and pathways resulting in the breakdown of a protein by pepsin in the stomach. Pepsin is generated from its precursor pepsinogen, which is activated by hydrolchloric acid (gastric acid).	tmpzr1t_l9r_go_relaxed.owl	protein breakdown by pepsin|protein degradation by pepsin					The reason for obsoletion is that this term represents a specific gene product.	GO:0030163				True			biological_process											owl:Class	
GO:0046233	biolink:NamedThing	obsolete 3-hydroxyphenylacetate biosynthetic process	OBSOLETE. The chemical reactions and pathways resulting in the formation of 3-hydroxyphenylacetate, 1,3-benzenediol monoacetate, also known as resorcinol monoacetate.	tmpzr1t_l9r_go_relaxed.owl	3-hydroxyphenylacetate anabolism|3-hydroxyphenylacetate biosynthetic process|3-hydroxyphenylacetate biosynthesis|3-hydroxyphenylacetate formation|3-hydroxyphenylacetate synthesis			GO:0019609		This term was made obsolete because 3-hydroxyphenylacetate is not synthesized by living organisms and GO does not cover non-biological processes.					True			biological_process											owl:Class	
GO:0075231	biolink:NamedThing	obsolete modulation of spore movement on or near host	OBSOLETE. Any process that modulates the frequency, rate or extent of spore movement on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it represented both a process and a location.					True			biological_process											owl:Class	
GO:0042029	biolink:NamedThing	obsolete fibrolase activity	OBSOLETE. Catalysis of the cleavage of 14-Ala-Leu-15 in insulin B chain and cleavage of 413-Lys-Leu-414 in alpha chain of fibrinogen.	tmpzr1t_l9r_go_relaxed.owl	Agkistrodon contortrix contortrix venom metalloproteinase activity|fibrinolytic proteinase activity|fibrolase activity|Agkistrodon contortrix contortrix metalloproteinase activity			GO:0004222		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:1990517	biolink:NamedThing	obsolete protein localization to photoreceptor outer segment	OBSOLETE. A process in which a protein is transported to, or maintained in, a location within a photoreceptor outer segment, which is a portion of a modified sensory cilium.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted at the TermGenie Gatekeeper stage.		krc	2014-10-14T14:01:34Z		True			biological_process											owl:Class	
GO:1904083	biolink:NamedThing	obsolete regulation of epiboly	OBSOLETE. Any process that modulates the frequency, rate or extent of epiboly.	tmpzr1t_l9r_go_relaxed.owl	regulation of epiboly					This term was obsoleted at the TermGenie Gatekeeper stage.		dos	2015-03-25T10:53:34Z		True			biological_process											owl:Class	
GO:0052198	biolink:NamedThing	obsolete modulation of peptidase activity in other organism involved in symbiotic interaction	OBSOLETE. The process in which an organism effects a change in peptidase activity, the catalysis of the hydrolysis of peptide bonds in a protein, in a second organism, where the two organisms are in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	modulation of protease activity in other organism involved in symbiotic interaction|modulation of protease activity in other organism during symbiotic interaction	https://github.com/geneontology/go-ontology/issues/21740				This term was obsoleted because it represents a molecular function.					True			biological_process											owl:Class	
GO:1990348	biolink:NamedThing	obsolete G/A mismatch specific adenine DNA glycosylase activity	OBSOLETE. Catalysis of the removal of adenine misinserted into nascent strand opposite guanine in the template by adenine DNA glycosylase activity. The reaction leaves an apurinic AP site. I also requested same term but for Go/A mismatch. If you think it is better to make one term for mismatched adenine that is fine by me.	tmpzr1t_l9r_go_relaxed.owl	G/A mismatch specific adenine DNA glycosylase activity					This term was obsoleted at the TermGenie Gatekeeper stage.		al	2014-03-25T10:55:45Z		True			molecular_function											owl:Class	
GO:0048191	biolink:NamedThing	obsolete peptide stabilization activity	OBSOLETE. Strengthening of a bond between peptides. Peptides are compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another.	tmpzr1t_l9r_go_relaxed.owl	peptide stabilization activity			GO:0050822		This term was made obsolete because it represents a biological process.					True			molecular_function											owl:Class	
GO:0019793	biolink:NamedThing	obsolete ISG15 carrier activity	OBSOLETE. Catalysis of the transfer of ISG15 (interferon-stimulated gene-15) from one side of the membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	ISG15 carrier activity|interferon-stimulated gene-15 carrier activity					This term was made obsolete because it is gene product-specific.					True			molecular_function											owl:Class	
GO:0097236	biolink:NamedThing	obsolete positive regulation of transcription from RNA polymerase II promoter in response to zinc ion starvation	OBSOLETE. Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of deprivation of zinc ions.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it represents a GO-CAM model.	GO:0045944|GO:0034224	pr	2012-02-01T09:33:11Z		True			biological_process											owl:Class	
GO:0016704	biolink:NamedThing	obsolete oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, miscellaneous	OBSOLETE. A grouping term for oxidoreductases acting on single donors with incorporation of molecular oxygen that cannot be more accurated categorized.	tmpzr1t_l9r_go_relaxed.owl	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, miscellaneous					This term was made obsolete because it was an unnecessary grouping term.	GO:0016701				True			molecular_function											owl:Class	
GO:0075105	biolink:NamedThing	obsolete negative regulation by host of symbiont calcium or calmodulin-mediated signal transduction	OBSOLETE. Any process in which the host organism stops, prevents, or reduces the frequency, rate or extent of calcium or calmodulin-mediated signal transduction in the symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	negative regulation by host of symbiont Ca++ or calmodulin-mediated signal transduction					The reason for obsoletion is that there is no evidence that the host can modulate or regulate a symbiont's signal transduction pathway.					True			biological_process											owl:Class	
GO:0015507	biolink:NamedThing	obsolete hydroxy/aromatic amino acid permease activity	OBSOLETE. Permease for hydroxy and aromatic amino acids.	tmpzr1t_l9r_go_relaxed.owl	hydroxy/aromatic amino acid permease activity					This term was made obsolete because it is a redundant grouping term.	GO:0015171|GO:0015173				True			molecular_function											owl:Class	
GO:0004624	biolink:NamedThing	obsolete secreted phospholipase A2 activity	OBSOLETE. Catalysis of the reaction: phosphatidylcholine + H2O = 1-acylglycerophosphocholine + a fatty acid anion.	tmpzr1t_l9r_go_relaxed.owl	secreted phospholipase A2 activity					This term was made obsolete because it represents component and function information.	GO:0005576|GO:0004623				True			molecular_function											owl:Class	
GO:0018327	biolink:NamedThing	obsolete enzyme active site formation via 1'-phospho-L-histidine	OBSOLETE. The transient phosphorylation of peptidyl-histidine to form 1'-phospho-L-histidine (otherwise known as tau-phosphohistidine, tele-phosphohistidine).	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/15594			RESID:AA0035	This term was obsoleted because it represents a reaction intermediate, not a biological process, see PMID:11038361.	GO:0008257				True			biological_process											owl:Class	
GO:0030617	biolink:NamedThing	obsolete transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity	OBSOLETE. A TGF-beta cytoplasmic mediator that inhibits the signaling function of common-partner and pathway-specific mediators.	tmpzr1t_l9r_go_relaxed.owl	TGFbeta receptor, inhibitory cytoplasmic mediator activity|TGF-beta receptor, inhibitory cytoplasmic mediator activity|inhibitory SMAD protein	https://github.com/geneontology/go-ontology/issues/16202				This term was obsoleted because it represents the same activity as GO:0140416 ; DNA-binding transcription factor inhibitor activity', occurs_in cytosol.	GO:0140416				True			molecular_function											owl:Class	
GO:0015376	biolink:NamedThing	obsolete betaine/GABA:sodium symporter activity	OBSOLETE. Catalysis of the reaction: (betaine or gamma-aminobutyric acid)(out) + Na+(out) = (betaine or gamma-aminobutyric acid)(in) + Na+(in).	tmpzr1t_l9r_go_relaxed.owl	betaine/GABA:sodium symporter activity					This term was made obsolete because it represents a multifunctional gene product.	GO:0005332|GO:0015370|GO:0015185|GO:0015199				True			molecular_function											owl:Class	
GO:0044189	biolink:NamedThing	obsolete host cell microsome	OBSOLETE. Any of the small, heterogeneous, artifactual, vesicular particles, 50-150 nm in diameter, that are formed when some eukaryotic host cells are homogenized and that sediment on centrifugation at 100000 g.	tmpzr1t_l9r_go_relaxed.owl	host cell microsome|host cell microsomal membrane					This term was obsoleted because it refers to a cell fractionation experimental result and not a bona fide cellular component.	GO:0033648	jl	2009-10-15T04:04:24Z		True			cellular_component											owl:Class	
GO:0000264	biolink:NamedThing	obsolete heterotrimeric G-protein GTPase, beta-subunit	OBSOLETE. Subunit of a heterotrimeric G-protein GTPase; associates tightly with the gamma subunit.	tmpzr1t_l9r_go_relaxed.owl	heterotrimeric G-protein GTPase, beta-subunit					This term was made obsolete because it does not represent a molecular function.	GO:0003924|GO:0005834				True			molecular_function											owl:Class	
GO:0042895	biolink:NamedThing	obsolete antibiotic transmembrane transporter activity	OBSOLETE. Enables the transfer of an antibiotic, a substance produced by or derived from certain fungi, bacteria, and other organisms, that can destroy or inhibit the growth of other microorganisms, from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	antibiotic transporter activity	https://github.com/geneontology/go-ontology/issues/17082				The reason for obsoletion is that this term has been inconsistently used. Consider annotating to 'GO:0042910 ; xenobiotic transmembrane transporter activity' and the specific solute being transported as an annotation extension.					True			molecular_function											owl:Class	
GO:0001170	biolink:NamedThing	obsolete transcription factor activity, RNA polymerase I enhancer sequence-specific binding	OBSOLETE. Binding to a RNA polymerase I (Pol I) enhancer in order to modulate transcription by RNA polymerase I.	tmpzr1t_l9r_go_relaxed.owl	RNA polymerase I enhancer sequence-specific DNA binding transcription factor activity	https://github.com/geneontology/go-ontology/issues/15787				This term was obsoleted because it represents two separate functions. The corresponding 'binding' term should be used in combination with a transcription regulator activity child.		krc	2011-02-03T04:10:59Z		True			molecular_function											owl:Class	
GO:0035954	biolink:NamedThing	obsolete positive regulation of dipeptide transport by positive regulation of transcription from RNA polymerase II promoter	OBSOLETE. Any process that activates or increases the frequency, rate or extent of dipeptide transport by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of dipeptide transport by activation of transcription from RNA polymerase II promoter|positive regulation of dipeptide transport by stimulation of transcription from RNA polymerase II promoter|positive regulation of dipeptide transport by up regulation of transcription from RNA polymerase II promoter|positive regulation of dipeptide transport by up-regulation of transcription from RNA polymerase II promoter|positive regulation of dipeptide transport by positive regulation of transcription from Pol II promoter|positive regulation of dipeptide transport by upregulation of transcription from RNA polymerase II promoter					This term was obsoleted because it represents a GO-CAM model.		bf			True			biological_process											owl:Class	
GO:0072468	biolink:NamedThing	obsolete signal transduction involved in cell shape checkpoint	OBSOLETE. A signal transduction process that contributes to a cell shape checkpoint.	tmpzr1t_l9r_go_relaxed.owl						This term was made obsolete because it was ambiguous.		mah	2010-12-09T11:45:12Z		True			biological_process											owl:Class	
GO:0090703	biolink:NamedThing	obsolete triplex DNA unwinding	OBSOLETE. The process by which a three-stranded D-loop DNA is unwound or 'melted'.	tmpzr1t_l9r_go_relaxed.owl						This term was made obsolete because it was created in error.		tb	2016-09-20T16:37:15Z		True			biological_process											owl:Class	
GO:0015001	biolink:NamedThing	obsolete high-potential iron-sulfur carrier	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	high-potential iron-sulfur carrier|HiPIP|high-potential iron-sulphur carrier			GO:0009055		This term was made obsolete because it refers to a class of gene products.					True			molecular_function											owl:Class	
GO:0042072	biolink:NamedThing	obsolete cell adhesion receptor inhibitor activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	cell adhesion receptor inhibitor activity					This term was made obsolete because it represents a gene product.	GO:0005102|GO:0007162				True			molecular_function											owl:Class	
GO:0008222	biolink:NamedThing	obsolete tumor antigen	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	tumor antigen					This term was made obsolete because it represents a gene product, and because describing something as an 'antigen' means that an organism can produce antibodies to it, which says nothing about the gene product activity.					True			molecular_function											owl:Class	
GO:0030439	biolink:NamedThing	obsolete activation of MAPK during sporulation (sensu Fungi)	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	activation of MAPK during sporulation (sensu Fungi)					This term was made obsolete because it is a gene product specific term.					True			biological_process											owl:Class	
GO:0052444	biolink:NamedThing	obsolete modulation by organism of defense-related symbiont salicylic acid-mediated signal transduction pathway	OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of symbiont salicylic acid-mediated signal transduction pathways during the symbiont defense response. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	modulation by organism of defense-related symbiont salicylic acid-mediated signal transduction pathway|modulation of defense-related symbiont SA-mediated signal transduction pathway by organism					This term was made obsolete because it does not represent a real biological process.					True			biological_process											owl:Class	
GO:0006197	biolink:NamedThing	obsolete adenylate deaminase reaction	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	adenylate deaminase reaction			GO:0003876		This term was made obsolete because it represents a molecular function.					True			biological_process											owl:Class	
GO:1990835	biolink:NamedThing	obsolete insulin-like growth factor production	OBSOLETE. The appearance of an insulin-like growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.	tmpzr1t_l9r_go_relaxed.owl	IGF production					This term was obsoleted at the TermGenie Gatekeeper stage.		sl	2015-08-24T16:30:53Z		True			biological_process											owl:Class	
GO:1905718	biolink:NamedThing	obsolete mitotic spindle astral microtubule end	OBSOLETE. Any microtubule end that is part of a mitotic spindle astral microtubule.	tmpzr1t_l9r_go_relaxed.owl	mitotic spindle astral microtubule tip					This term was obsoleted at the TermGenie Gatekeeper stage.		vw	2016-11-24T14:30:11Z		True			cellular_component											owl:Class	
GO:0015025	biolink:NamedThing	obsolete GPI-anchored membrane-bound receptor	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	GPI-anchored membrane-bound receptor			GO:0031225		This term was made obsolete because it contains both component and function information.					True			molecular_function											owl:Class	
GO:0042655	biolink:NamedThing	obsolete activation of JNKKK activity	OBSOLETE. The initiation of the activity of the inactive enzyme JUN kinase kinase kinase (JNKKK) activity.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of JUNKKK activity|activation of JUN kinase kinase kinase activity	https://github.com/geneontology/go-ontology/issues/21307				This term was obsoleted because it represents a molecular function.	GO:0007254|GO:0043539				True			biological_process											owl:Class	
GO:0023066	biolink:NamedThing	obsolete signal transmission via vascular system	OBSOLETE. The process in which a signal is conveyed via the vascular system.	tmpzr1t_l9r_go_relaxed.owl	signal transmission via vascular system					This term was made obsolete because the meaning of the term is ambiguous.	GO:0023052|GO:0010232		2010-02-16T09:30:50Z		True			biological_process											owl:Class	
GO:0051196	biolink:NamedThing	obsolete regulation of coenzyme metabolic process	OBSOLETE. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a coenzyme.	tmpzr1t_l9r_go_relaxed.owl	regulation of coenzyme and prosthetic group metabolism|regulation of coenzyme and prosthetic group metabolic process|regulation of coenzyme metabolism					1. Making inferences in GO about compounds based on the coenzyme role curated by ChEBI creates relationships that are not always true which violates ontological principles for GO; therefore we will cease making these inferences. 2. It is not meaningful to group metabolic processes that are not all metabolically related by the fact that they may be used as a coenzyme.					True			biological_process											owl:Class	
GO:0015073	biolink:NamedThing	obsolete phosphatidylinositol 3-kinase, class I, regulator activity	OBSOLETE. Catalysis of the reaction: ATP + 1-phosphatidyl-1D-myo-inositol = ADP + 1-phosphatidyl-1D-myo-inositol 3-phosphate.	tmpzr1t_l9r_go_relaxed.owl	phosphatidylinositol 3-kinase, class I, regulator activity			GO:0046935		This term was made obsolete because it refers to a class of gene products.					True			molecular_function											owl:Class	
GO:0000260	biolink:NamedThing	obsolete hydrogen-translocating V-type ATPase activity	OBSOLETE. Catalysis of the reaction: ATP + H2O + H(+)(in) = ADP + phosphate + H+(out). Found in vacuoles of eukaryotes and in bacteria.	tmpzr1t_l9r_go_relaxed.owl	hydrogen-translocating V-type ATPase activity			GO:0046961		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0006630	biolink:NamedThing	obsolete lipid binding	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	lipid binding					This term was made obsolete because it represents a molecular function and not a biological process.	GO:0008289				True			biological_process											owl:Class	
GO:0055124	biolink:NamedThing	obsolete premature neural plate formation	OBSOLETE. The formation of the neural plate before the appropriate time.	tmpzr1t_l9r_go_relaxed.owl	premature neural plate formation										True			biological_process											owl:Class	
GO:0015634	biolink:NamedThing	obsolete lipopolysaccharide exporter activity	OBSOLETE. Enables the transfer of lipopolysaccharide from the inside of the cell to the outside of the cell across a membrane. A lipopolysaccharide is any of a group of related, structurally complex components of the outer membrane of Gram-negative bacteria. Lipopolysaccharides consist three covalently linked regions, lipid A, core oligosaccharide, and an O side chain. Lipid A is responsible for the toxicity of the lipopolysaccharide.	tmpzr1t_l9r_go_relaxed.owl	LPS exporter activity	https://github.com/geneontology/go-ontology/issues/17202				This term was obsoleted because export is a process, not a function.					True			molecular_function											owl:Class	
GO:0023070	biolink:NamedThing	obsolete signal transmission via air	OBSOLETE. The process in which a signal is conveyed via the air.	tmpzr1t_l9r_go_relaxed.owl	signal transmission via air					This term was made obsolete because the meaning of the term is ambiguous.			2010-02-16T09:30:50Z		True			biological_process											owl:Class	
GO:2001274	biolink:NamedThing	obsolete negative regulation of glucose import in response to insulin stimulus	OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of glucose import in response to insulin stimulus.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of cellular glucose import in response to insulin stimulus	https://github.com/geneontology/go-ontology/issues/15961						vk	2011-12-13T12:29:38Z		True			biological_process											owl:Class	
GO:0004253	biolink:NamedThing	obsolete gamma-renin activity	OBSOLETE. Catalysis of the cleavage of the Leu-Leu bond in synthetic tetradecapeptide renin substrate, producing angiotensin I, but not active on natural angiotensinogen. Also hydrolyzes BZ-Arg-para-nitroanilide.	tmpzr1t_l9r_go_relaxed.owl	gamma-renin activity			GO:0004252		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0001528	biolink:NamedThing	obsolete elastin	OBSOLETE. A major structural protein of mammalian connective tissues; composed of one third glycine, and also rich in proline, alanine, and valine. Chains are cross-linked together via lysine residues.	tmpzr1t_l9r_go_relaxed.owl	elastin			GO:0030023		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0051853	biolink:NamedThing	obsolete induction in symbiont of tumor, nodule, or growth	OBSOLETE. The process by which an associated organism causes the formation of an abnormal mass of cells in the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	induction in symbiont of tumor, nodule, or growth	https://github.com/geneontology/go-ontology/issues/18605				This term was made obsolete because it does not represent a real process that exists in nature.					True			biological_process											owl:Class	
GO:0052488	biolink:NamedThing	obsolete negative regulation by organism of pathogen-associated molecular pattern-induced symbiont innate immunity	OBSOLETE. This term was not defined before being made obsolete.	tmpzr1t_l9r_go_relaxed.owl	suppression of general elicitor-induced symbiont innate immunity|suppression of pathogen-associated molecular pattern-induced symbiont innate immunity|negative regulation by organism of pathogen-associated molecular pattern-induced symbiont innate immunity|suppression of PAMP induced symbiont innate immunity|suppression of MAMP induced symbiont innate immunity|suppression of MAMP-induced symbiont innate immunity|suppression of general elicitor induced symbiont innate immunity|suppression of PAMP-induced symbiont innate immunity					This term was made obsolete because it does not represent a real biological process.					True			biological_process											owl:Class	
GO:0052463	biolink:NamedThing	obsolete modulation by organism of symbiont phytoalexin production	OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of production of phytoalexins as part of the defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	modulation by organism of symbiont phytoalexin production					This term was made obsolete because it does not represent a real biological process.					True			biological_process											owl:Class	
GO:0000267	biolink:NamedThing	obsolete cell fraction	OBSOLETE. A generic term for parts of cells prepared by disruptive biochemical techniques.	tmpzr1t_l9r_go_relaxed.owl	cell fraction					This term was made obsolete because it refers to a cell fractionation experimental result and not a bona fide cellular component.	GO:0005575				True			cellular_component											owl:Class	
GO:0090420	biolink:NamedThing	obsolete naphthalene-containing compound metabolic process	OBSOLETE. The chemical reactions and pathways involving naphthalene-containing compounds.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it is a unnecessary grouping class.		tb	2011-12-12T11:32:34Z		True			biological_process											owl:Class	
GO:0030401	biolink:NamedThing	obsolete transcription antiterminator activity	OBSOLETE. Functions to prevent the termination of RNA synthesis. Acts as a regulatory device, e.g. in phage lambda, enabling a terminator to be masked from RNA polymerase so that distal genes can be expressed.	tmpzr1t_l9r_go_relaxed.owl	transcription antiterminator activity|transcriptional antiterminator activity					This term was obsoleted because it is essentially identical to a Process term (specifically the Biological Process term which has been selected as a term to consider for reannotation), i.e. it is defined only in terms of the process it acts in and it does NOT convey any information about the molecular nature of the function or whether the function is based on binding DNA, on interacting with other proteins, or some other mechanism. To transfer all annotations without review, the BP term indicated is considered to be equivalent and thus the only appropriate destination for all annotations. To reannotate to a MF term, you will probably need to revisit the original literature or other primary data because this "MF" term was not defined in terms of mechanism of action and there are multiple possibilities in the revised MF structure. In reannotation, please also consider descendent terms of the suggested MF terms as a more specific term may be more appropriate than the MF terms indicated. Please be aware that you may wish to request a new term if the mechanism of action of this gene product is not yet represented or if you are annotating for an RNAP different than one for which there is a specific suggested term. Also note that if there is no information about how the gene product acts, it may be appropriate to annotate to the root term for molecular_function.	GO:0006353|GO:0001073|GO:0001072				True			molecular_function											owl:Class	
GO:0075062	biolink:NamedThing	obsolete regulation of invasive hypha growth	OBSOLETE. Any process that modulates the frequency, rate or extent of symbiont invasive hypha formation within host. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	regulation of symbiont invasive hypha formation within host|regulation of symbiont invasive hypha formation in host	https://github.com/geneontology/go-ontology/issues/19013				This term was obsoleted because there is no evidence that this process exists.					True			biological_process											owl:Class	
GO:0100006	biolink:NamedThing	obsolete positive regulation of sulfite transport by transcription from RNA polymerase II promoter	OBSOLETE. Any transcription from RNA polymerase II promoter process that positively regulates sulfite transport.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it represents a GO-CAM model.		cjm	2015-04-02T04:13:19Z		True			biological_process											owl:Class	
GO:0003901	biolink:NamedThing	obsolete DNA-directed RNA polymerase II activity	OBSOLETE. Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1).	tmpzr1t_l9r_go_relaxed.owl	DNA-directed RNA polymerase II activity			GO:0003899		This term was made obsolete because it represents the specific complex represented by the cellular component term 'DNA-directed RNA polymerase II, core complex ; GO:0005665'.					True			molecular_function											owl:Class	
GO:0044137	biolink:NamedThing	obsolete growth of symbiont on or near host rhizosphere	OBSOLETE. The increase in size or mass of symbiont occurring on or near its host rhizosphere. The host rhizosphere is defined as total below-ground surfaces of a plant as a habitat for its symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/18786				This term was obsoleted because it represents both a process and a location.		jl	2009-08-04T04:19:07Z		True			biological_process											owl:Class	
GO:0043677	biolink:NamedThing	obsolete germination pore	OBSOLETE. A small pore in the outer wall of a mycelial spore through which the germ tube exits upon germination. It can be apical or eccentric in its location.	tmpzr1t_l9r_go_relaxed.owl	germ pore				Wikipedia:Germ_pore	This term was made obsolete because it was poorly named and poorly defined.					True			cellular_component											owl:Class	
GO:0039559	biolink:NamedThing	obsolete suppression by virus of host IRF7 activity by positive regulation of IRF7 catabolic process	OBSOLETE. Any process in which a virus stops, prevents, or reduces the activity of host IRF7 (interferon regulatory factor-7) by promoting the ubiquitin-dependent degradation of IRF7, mediated by the proteasome.	tmpzr1t_l9r_go_relaxed.owl	promotion by virus of proteosome-dependent IRF7 degradation					The reason for obsoleting this term is that it is too specific. The exact molecular roles of the individual proteins should be captured separately.		bf	2012-03-09T04:38:58Z		True			biological_process											owl:Class	
GO:0042990	biolink:NamedThing	obsolete regulation of transcription factor import into nucleus	OBSOLETE. Any process that modulates the frequency, rate or extent of the movement of a transcription factor from the cytoplasm to the nucleus.	tmpzr1t_l9r_go_relaxed.owl	regulation of transcription factor transport from cytoplasm to nucleus|regulation of transcription factor import into cell nucleus|regulation of transcription factor-nucleus import					The reason for obsoletion is that there is no distinct pathway to import transcription factors into the nucleus.	GO:0042306				True			biological_process											owl:Class	
GO:0008435	biolink:NamedThing	obsolete anticoagulant activity	OBSOLETE. Functions to retard or prevent coagulation. Often used in the context of blood or milk coagulation.	tmpzr1t_l9r_go_relaxed.owl	anticoagulant activity			GO:0050819		This term was made obsolete because it represents a biological process.					True			molecular_function											owl:Class	
GO:0052484	biolink:NamedThing	obsolete negative regulation by organism of symbiont ethylene-mediated defense response	OBSOLETE. Any process by which an organism stops, prevents, or reduces the frequency, rate or extent of the ethylene-mediated defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	negative regulation by organism of symbiont ethylene-mediated defense response|suppression by organism of symbiont ethylene-mediated defense response					This term was made obsolete because it does not represent a real biological process.					True			biological_process											owl:Class	
GO:0050425	biolink:NamedThing	obsolete carboxypeptidase B activity	OBSOLETE. Catalysis of the reaction: H2O + peptidyl-L-lysine (or L-arginine) = L-lysine (or L-arginine) + peptide. Preferential release of a C-terminal lysine or arginine amino acid.	tmpzr1t_l9r_go_relaxed.owl	protaminase activity|peptidyl-L-lysine [L-arginine]hydrolase activity|tissue carboxypeptidase B|carboxypeptidase B activity|pancreatic carboxypeptidase B			GO:0004181		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0009839	biolink:NamedThing	obsolete SCF complex substrate recognition subunit	OBSOLETE. The portion of the SCF ubiquitin ligase complex that contains sites required for recognition (and recruitment) of the substrate to the complex.	tmpzr1t_l9r_go_relaxed.owl	SCF complex substrate recognition subunit			GO:0019005		This term was made obsolete because it represents a single gene product and not a complex.					True			cellular_component											owl:Class	
GO:0044040	biolink:NamedThing	obsolete multi-organism carbohydrate metabolic process	OBSOLETE. The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y, that involve more than one organism.	tmpzr1t_l9r_go_relaxed.owl	main pathways of carbohydrate metabolism|multi-organism carbohydrate metabolism|main pathways of carbohydrate metabolic process					This term was obsoleted because there is no evidence that this process exists.					True			biological_process											owl:Class	
GO:0008337	biolink:NamedThing	obsolete selectin	OBSOLETE. A class of cell adhesion molecules that bind to carbohydrate via a lectin-like domain; integral membrane glycoproteins.	tmpzr1t_l9r_go_relaxed.owl	selectin					This term was made obsolete because it describes a class of gene products.	GO:0030246|GO:0007155|GO:0050839|GO:0016021|GO:0005102				True			molecular_function											owl:Class	
GO:0008001	biolink:NamedThing	obsolete fibrinogen	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	fibrinogen			GO:0005577		This term was made obsolete because it does not describe an activity.					True			molecular_function											owl:Class	
GO:0019987	biolink:NamedThing	obsolete negative regulation of anti-apoptosis	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of anti-apoptosis.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of anti-apoptosis|downregulation of anti-apoptosis|down regulation of anti-apoptosis|down-regulation of anti-apoptosis|inhibition of anti-apoptosis					This term was made obsolete because it was ill-defined.					True			biological_process											owl:Class	
GO:0090412	biolink:NamedThing	obsolete positive regulation of transcription from RNA polymerase II promoter involved in fatty acid biosynthetic process	OBSOLETE. Any positive regulation of transcription from RNA polymerase II promoter that is involved in fatty acid biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of transcription from RNA polymerase II promoter involved in fatty acid biosynthetic process						GO:0045944	tb	2011-09-01T03:10:41Z		True			biological_process											owl:Class	
GO:0003107	biolink:NamedThing	obsolete positive regulation of natriuresis by angiotensin	OBSOLETE. The process in which angiotensin increases the rate of natriuresis indirectly via diuresis. Natriuresis is the process of renal sodium excretion.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of natriuresis by angiotensin|angiotensin-mediated positive regulation of natriuresis					This term was made obsolete because the term is misleading.					True			biological_process											owl:Class	
GO:0045566	biolink:NamedThing	obsolete positive regulation of TRAIL receptor 1 biosynthetic process	OBSOLETE. Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of TRAIL (TNF-related apoptosis inducing ligand) receptor 1.	tmpzr1t_l9r_go_relaxed.owl	stimulation of TRAIL receptor 1 biosynthetic process|positive regulation of TRAIL receptor 1 anabolism|upregulation of TRAIL receptor 1 biosynthetic process|positive regulation of TRAIL receptor 1 formation|positive regulation of TRAIL receptor 1 biosynthesis|up regulation of TRAIL receptor 1 biosynthetic process|activation of TRAIL receptor 1 biosynthetic process|positive regulation of TRAIL receptor 1 synthesis|up-regulation of TRAIL receptor 1 biosynthetic process	https://github.com/geneontology/go-ontology/issues/19900				The reason for obsoletion is that those represent specific gene products, and genes annotated to those terms should be annotated to 'regulation of gene expression' or 'regulation of transcription' or some signaling term.					True			biological_process											owl:Class	
GO:1990865	biolink:NamedThing	obsolete response to intermittent hypoxia	OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an episodic stimulus indicating lowered oxygen tension.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted at the TermGenie Gatekeeper stage.		sl	2015-09-25T15:07:32Z		True			biological_process											owl:Class	
GO:0046021	biolink:NamedThing	obsolete regulation of transcription from RNA polymerase II promoter during mitotic cell cycle	OBSOLETE. A cell cycle process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that occurs during the mitotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl	regulation of transcription from Pol II promoter, mitotic|mitotic regulation of transcription from Pol II promoter|regulation of transcription from RNA polymerase II promoter during mitosis	https://github.com/geneontology/go-ontology/issues/14896				The reason for obsoletion is that 'during' should be captured using an annotation extension.	GO:0044772|GO:0006357				True			biological_process											owl:Class	
GO:0052169	biolink:NamedThing	obsolete pathogen-associated molecular pattern dependent modulation by symbiont of host innate immune response	OBSOLETE. Any process that involves recognition of a pathogen-associated molecular pattern, and by which an organism modulates the frequency, rate or extent of the innate immune response of the host organism; the innate immune response is the host's first line of defense against infection. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	pathogen-associated molecular pattern dependent modulation by symbiont of host innate immunity					This term was obsoleted because it has been misused.	GO:0002221|GO:0002752|GO:0052034				True			biological_process											owl:Class	
GO:0033747	biolink:NamedThing	obsolete versatile peroxidase activity	OBSOLETE. Catalysis of the reactions: Reactive Black 5 + hydrogen peroxide = oxidized Reactive Black 5 + 2 H2O, and donor + hydrogen peroxide = oxidized donor + 2 H2O.	tmpzr1t_l9r_go_relaxed.owl	VP|reactive-black-5:hydrogen-peroxide oxidoreductase activity|polyvalent peroxidase activity|versatile peroxidase activity|hybrid peroxidase activity			GO:0004601			GO:0052750				True			molecular_function											owl:Class	
GO:0005177	biolink:NamedThing	obsolete neuroligin	OBSOLETE. A class of ligands for neurexins.	tmpzr1t_l9r_go_relaxed.owl	neuroligin						GO:0042043				True			molecular_function											owl:Class	
GO:1903155	biolink:NamedThing	obsolete glutathione transmembrane transporter activity involved in glutathione import into cell	OBSOLETE. Any glutathione transmembrane transporter activity that is involved in glutathione import into cell.	tmpzr1t_l9r_go_relaxed.owl	glutathione transmembrane transporter activity involved in glutathione uptake|glutathione transmembrane transporter activity involved in glutathione import into cell					This term was obsoleted at the TermGenie Gatekeeper stage.		dos	2014-07-09T11:56:05Z		True			molecular_function											owl:Class	
GO:0050478	biolink:NamedThing	obsolete anthranilate 3-monooxygenase activity	OBSOLETE. Catalysis of the reaction: 5,6,7,8-tetrahydrobiopterin + anthranilate + O(2) = 3-hydroxyanthranilate + 7,8-dihydrobiopterin + H(2)O.	tmpzr1t_l9r_go_relaxed.owl	anthranilate 3-hydroxylase activity|anthranilate,tetrahydrobiopterin:oxygen oxidoreductase (3-hydroxylating)|anthranilic acid hydroxylase activity					This term is slated for obsoletion;  According to RHEA the activity does not exist.					True			molecular_function											owl:Class	
GO:1990568	biolink:NamedThing	obsolete MIS18 complex	OBSOLETE. A centromere complex assembly protein that is required for the deposition of CENP-A on the centromere. The Mis18 complex localizes to centromeres just prior to the pre-nucleosomal HJURP/CENP-A/H4 complex and is absolutely required for the CENP-A-specific chaperone, Holliday junction recognition protein (HJURP) to reach the centromeres. Plk1 phosphorylation activates Mis18 complex recruitment to the centromeres during G1. CDK phosphorylation of MISBP1 during G2 and mitosis, prior to the metaphase-to-anaphase transition, negatively regulates complex assembly.	tmpzr1t_l9r_go_relaxed.owl	MIS18 complex					An example of this is MIS18A in human (Q9NYP9) in PMID:25036634 (inferred from physical interaction).		bhm	2014-11-27T10:52:20Z		True			cellular_component											owl:Class	
GO:1901916	biolink:NamedThing	obsolete protein kinase activity involved in regulation of protein localization to cell division site involved in cytokinesis	OBSOLETE. Any protein kinase activity that is involved in regulation of protein localization to cell division site involved in cytokinesis.	tmpzr1t_l9r_go_relaxed.owl	protein kinase activity involved in regulation of protein localisation to cell division site involved in cytokinesis|protamine kinase activity involved in regulation of protein localisation to cell division site involved in cytokinesis|protamine kinase activity involved in regulation of protein localization to cell division site involved in cytokinesis	https://github.com/geneontology/go-ontology/issues/20226				This term was obsoleted is that this term represents both a function and a process.		dph	2013-02-14T15:30:37Z		True			molecular_function											owl:Class	
GO:0071687	biolink:NamedThing	obsolete horsetail nucleus leading edge	OBSOLETE. The part of the horsetail nucleus where telomeres cluster under the SPB and that leads horsetail movement. The horsetail nucleus is the elongated nucleus which forms during the rapid oscillatory movement at meiotic prophase; characterized in Schizosaccharomyces pombe.	tmpzr1t_l9r_go_relaxed.owl						This term was made obsolete at the request of PomBase as the concept can be expressed by annotating to a less granular term and using annotation extensions.		mah	2010-02-22T05:04:40Z		True			cellular_component											owl:Class	
GO:0006987	biolink:NamedThing	obsolete activation of signaling protein activity involved in unfolded protein response	OBSOLETE. The conversion of a specific protein, possessing protein kinase and endoribonuclease activities, to an active form as a result of signaling via the unfolded protein response.	tmpzr1t_l9r_go_relaxed.owl	unfolded protein response, activation of signalling protein kinase/endonuclease|unfolded protein response, activation of signaling protein activity|unfolded protein response, activation of signaling protein kinase/endonuclease					The reason for obsoletion is that this process represents a single step (molecular function) of the IRE1-mediated unfolded protein response (GO:0036498).	GO:0036498				True			biological_process											owl:Class	
GO:1990382	biolink:NamedThing	obsolete melanosome assembly	OBSOLETE. The aggregation, arrangement and bonding together of a set of components to form a melanosome, a tissue-specific, membrane-bounded cytoplasmic organelle within which melanin pigments are synthesized and stored.	tmpzr1t_l9r_go_relaxed.owl	melanosome biogenesis					This term was obsoleted at the TermGenie Gatekeeper stage.		bf	2014-05-20T16:06:04Z		True			biological_process											owl:Class	
GO:0042080	biolink:NamedThing	obsolete GPI/GSI anchor biosynthetic process	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	GPI/GSI anchor synthesis|GPI/GSI anchor biosynthesis|GPI/GSI anchor anabolism|GPI/GSI anchor formation|GPI/GSI anchor biosynthetic process					This term was made obsolete because it is a composite term that represents two individual processes.	GO:0042082|GO:0006506				True			biological_process											owl:Class	
GO:0003787	biolink:NamedThing	obsolete actin depolymerizing activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	actin depolymerizing activity			GO:0030042		This term was made obsolete because it represents a biological process.					True			molecular_function											owl:Class	
GO:1990844	biolink:NamedThing	obsolete interfibrillar mitochondrion	OBSOLETE. A mitochondrion that occurs in between fibrils of striated muscle cells and responds in distinct ways to physiological triggers.	tmpzr1t_l9r_go_relaxed.owl	IMF mitochondrion|IFM|intermyofibrillar mitochondrion					This term was obsoleted because it corresponds to mitochondria of specific cell types and this information should be captured as an extension.		sl	2015-08-31T16:26:44Z		True			cellular_component											owl:Class	
GO:0052511	biolink:NamedThing	obsolete positive regulation by organism of symbiont ethylene-mediated defense response	OBSOLETE. Any process by which an organism activates, maintains or increases the frequency, rate or extent of the ethylene-mediated defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	positive regulation by organism of symbiont ethylene-mediated defense response|activation by organism of symbiont ethylene-mediated defense response|induction by organism of symbiont ethylene-mediated defense response|upregulation by organism of symbiont ethylene-mediated defense response					This term was made obsolete because it does not represent a real biological process.					True			biological_process											owl:Class	
GO:0015070	biolink:NamedThing	obsolete toxin activity	OBSOLETE. Acts as to cause injury to other living organisms.	tmpzr1t_l9r_go_relaxed.owl	toxin activity					This term was made obsolete because it represents a classification of molecules and not a molecular function.	GO:0090729				True			molecular_function											owl:Class	
GO:0006608	biolink:NamedThing	obsolete snRNP protein import into nucleus	OBSOLETE. The directed movement of a small nuclear ribonucleoprotein from the cytoplasm into the nucleus, across the nuclear membrane.	tmpzr1t_l9r_go_relaxed.owl	snRNP protein-nucleus import|snRNP protein import into cell nucleus|snRNP protein transport from cytoplasm to nucleus					The reason for obsoletion is that all proteins are imported into the nucleus via the same mechanism, so the import of individual proteins should be captured with extensions or by GO-CAM models.	GO:0006606				True			biological_process											owl:Class	
GO:0009983	biolink:NamedThing	obsolete tyrosine aminopeptidase activity	OBSOLETE. Catalysis of the release of N-terminal tyrosine from a peptide.	tmpzr1t_l9r_go_relaxed.owl	tyrosine aminopeptidase activity			GO:0004177		This term was made obsolete because it represents a gene product, and the substrate specificity it refers to is not cleanly defined.					True			molecular_function											owl:Class	
GO:0009459	biolink:NamedThing	obsolete cytochrome a	OBSOLETE. A cytochrome containing heme a.	tmpzr1t_l9r_go_relaxed.owl	cytochrome a			GO:0004129		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0010681	biolink:NamedThing	obsolete cinnamic acid biosynthetic process involved in stilbene metabolism	OBSOLETE. The chemical reactions and pathways resulting in the formation of cinnamic acid, 3-phenyl-2-propenoic acid, which is then utilized in the metabolism of stilbene.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/18200				This term was obsoleted because it does not represent a specific pathway.					True			biological_process											owl:Class	
GO:1900391	biolink:NamedThing	obsolete regulation of cAMP-mediated signaling by regulation of transcription from RNA polymerase II promoter	OBSOLETE. A regulation of transcription from RNA polymerase II promoter that results in regulation of cAMP-mediated signaling.	tmpzr1t_l9r_go_relaxed.owl	regulation of cAMP-mediated signalling by regulation of transcription from RNA polymerase II promoter	https://github.com/geneontology/go-ontology/issues/14279				The reason for obsoletion is that cAMP-mediated signaling is not mediated by transcription from RNA polII promoter.		mah	2012-04-18T04:19:39Z		True			biological_process											owl:Class	
GO:0045307	biolink:NamedThing	obsolete activator of the establishment of competence for transformation activity	OBSOLETE. Activates the establishment of competence for transformation.	tmpzr1t_l9r_go_relaxed.owl	activator of the establishment of competence for transformation activity			GO:0045809		This term was made obsolete because it does not represent a true function.					True			molecular_function											owl:Class	
GO:0030438	biolink:NamedThing	obsolete MAPKKK cascade during sporulation (sensu Fungi)	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	MAPKKK cascade during sporulation (sensu Fungi)					This term was made obsolete because it is a gene product specific term.					True			biological_process											owl:Class	
GO:0001559	biolink:NamedThing	obsolete regulation of cell growth by detection of nuclear:cytoplasmic ratio	OBSOLETE. Any process in which the size of the nucleus with respect to the cytoplasm modulates the frequency, rate or extent of cell growth, the irreversible increase in size of a cell over time.	tmpzr1t_l9r_go_relaxed.owl	regulation of cell growth by nuclear:cytoplasmic ratio|regulation of cell growth by sensing of nuclear:cytoplasmic ratio|detection of nuclear:cytoplasmic ratio to regulate cell growth|interpretation of nuclear:cytoplasmic ratio to regulate cell growth					This term was obsoleted because there is no evidence that this process exists.					True			biological_process											owl:Class	
GO:0018326	biolink:NamedThing	obsolete enzyme active site formation via S-acetyl-L-cysteine	OBSOLETE. The transient acetylation of peptidyl-cysteine to form S-acetyl-L-cysteine.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/15594			RESID:AA0056	This term was obsoleted because it represents a reaction intermediate, not a biological process, see PMID:1310545.					True			biological_process											owl:Class	
GO:0016026	biolink:NamedThing	obsolete proteasome endopeptidase core	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	proteasome endopeptidase core					This term was made obsolete because it does not represent a molecular function.	GO:0004175				True			molecular_function											owl:Class	
GO:0045889	biolink:NamedThing	obsolete positive regulation of transcription of homeotic gene (Polycomb group)	OBSOLETE. Any process that activates or increases the frequency, rate or extent of transcription of homeotic genes of the Polycomb group.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of transcription of homeotic gene (Polycomb group)					This term was made obsolete because it relates to a specific gene family rather than a process.	GO:0045944				True			biological_process											owl:Class	
GO:0039605	biolink:NamedThing	obsolete TFIIB-class transcription factor binding involved in viral suppression of host transcription initiation from RNA polymerase II promoter	OBSOLETE. Selective and non-covalent interaction of a viral protein with a member of the TFIIB-class of host transcription factors, which contributes to the viral-suppression of assembly of the RNA polymerase II preinitiation complex (PIC) at an RNA polymerase II promoter region of a host DNA template.	tmpzr1t_l9r_go_relaxed.owl						The reason for obsoleting this term is that it is too specific. The exact molecular roles of the individual proteins should be captured separately.		bf	2012-07-05T04:16:45Z		True			molecular_function											owl:Class	
GO:0052711	biolink:NamedThing	obsolete ergothioneine biosynthesis from N-alpha,N-alpha,N-alpha-trimethyl-L-histidine	OBSOLETE. The pathway resulting in the formation of ergothioneine from N-alpha,N-alpha,N-alpha-trimethyl-L-histidine (also known as hercynine or histidine betaine).	tmpzr1t_l9r_go_relaxed.owl	N-alpha,N-alpha,N-alpha-trimethyl-L-histidine catabolism to ergothioneine|histidine betaine catabolism to ergothioneine|ergothioneine biosynthesis from histidine betaine|ergothioneine biosynthesis from hercynine|hercynine catabolism to ergothioneine	https://github.com/geneontology/go-ontology/issues/11163			KEGG_REACTION:R04878	The reason for obsoletion is that this term does not provide a useful distinction from its parent, GO:0052704 (because that trimethyl-His yada is present in both pathways)			2011-08-05T04:06:16Z		True			biological_process											owl:Class	
GO:0007590	biolink:NamedThing	obsolete fat body metabolic process (sensu Insecta)	OBSOLETE. The chemical reactions and pathways involving the fat body. A fat body is a fat-containing cellular structure which serves as an energy reserve. As in, but not restricted to, the true insects (Insecta, ncbi_taxonomy_id:50557).	tmpzr1t_l9r_go_relaxed.owl	fat body metabolic process (sensu Insecta)					This term was made obsolete because it represents metabolism within the fat body not of the fat body.					True			biological_process											owl:Class	
GO:2000462	biolink:NamedThing	obsolete positive regulation of eukaryotic cell surface binding	OBSOLETE. Any process that activates or increases the frequency, rate or extent of eukaryotic cell surface binding.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of eukaryotic cell surface binding					This term was made obsolete because the cell surface binding terms are ambiguous grouping terms and were causing confusion.	GO:1900122|GO:0031347	yaf	2011-03-04T12:00:49Z		True			biological_process											owl:Class	
GO:1900467	biolink:NamedThing	obsolete regulation of cellular potassium ion homeostasis	OBSOLETE. Any process that modulates the frequency, rate or extent of cellular potassium ion homeostasis.	tmpzr1t_l9r_go_relaxed.owl	regulation of cellular potassium ion homeostasis					This term was obsoleted at the TermGenie Gatekeeper stage.		dgf	2012-05-01T07:48:07Z		True			biological_process											owl:Class	
GO:1901311	biolink:NamedThing	obsolete regulation of gene expression involved in extracellular matrix organization	OBSOLETE. Any process that modulates the frequency, rate or extent of gene expression involved in extracellular matrix organization.	tmpzr1t_l9r_go_relaxed.owl	regulation of expression of extracellular matrix proteins|regulation of extracellular matrix protein production					This term was made obsolete is that in these terms the 'involved in' process is not truly involved_in (i.e. part_of) the process but instead is causally upstream of it. We advise replacing annotations to these terms with annotations + extensions using the causally_upstream_of relation e.g. P1234 regulation of gene expression [causally_upstream_of] extracellular matrix organization.	GO:0010468	vk	2012-08-22T09:18:13Z		True			biological_process											owl:Class	
GO:0036523	biolink:NamedThing	obsolete induction by symbiont of host cytokine production	OBSOLETE. Any process in which a symbiont activates, maintains or increases the frequency, rate or extent of cytokine production by the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	'induction by symbiont of host cytokine secretion'|positive regulation by symbiont of host cytokine secretion|induction by symbiont of host cytokine secretion	https://github.com/geneontology/go-ontology/issues/21743				This term was obsoleted because it does not represent a real process.		bf	2016-06-06T14:53:54Z		True			biological_process											owl:Class	
GO:0016551	biolink:NamedThing	obsolete posttranscriptional insertion or deletion editing	OBSOLETE. The insertion into or deletion from an RNA molecule of nucleotide residues not encoded in DNA; takes place after transcription.	tmpzr1t_l9r_go_relaxed.owl	posttranscriptional insertion/deletion editing|posttranscriptional insertion or deletion editing					This term was made obsolete because it represents two separate processes (insertion and deletion).	GO:0070706|GO:0070705				True			biological_process											owl:Class	
GO:0052515	biolink:NamedThing	obsolete positive regulation by organism of symbiont innate immunity	OBSOLETE. Any process by which an organism activates, maintains or increases the frequency, rate or extent of the innate immune response of the symbiont organism; the innate immune response is the symbiont's first line of defense against infection. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	positive regulation by organism of symbiont innate immunity|positive regulation of symbiont innate immune response					This term was made obsolete because it does not represent a real biological process.					True			biological_process											owl:Class	
GO:1901486	biolink:NamedThing	obsolete negative regulation of SREBP signaling pathway by positive regulation of transcription factor catabolic process	OBSOLETE. Positive regulation of transcription factor catabolism that results in negative regulation of the SREBP signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of SREBP-mediated signaling pathway by positive regulation of transcription factor catabolic process|negative regulation of SREBP-mediated signalling pathway by positive regulation of transcription factor catabolic process|negative regulation of SREBP signaling pathway by positive regulation of transcription factor catabolism|negative regulation of SREBP signaling pathway by positive regulation of SREBP degradation					The reason for obsoletion is that this term should be represented by a GO-CAM model.		bf	2012-10-09T08:23:26Z		True			biological_process											owl:Class	
GO:0015303	biolink:NamedThing	obsolete galactose, glucose uniporter activity	OBSOLETE. Catalysis of the reaction: galactose or glucose(out) = galactose or glucose(in).	tmpzr1t_l9r_go_relaxed.owl	galactose, glucose uniporter activity					This term was made obsolete because it represents two molecular functions.	GO:0050782|GO:0015304				True			molecular_function											owl:Class	
GO:0038081	biolink:NamedThing	obsolete MAP kinase kinase kinase activity involved in osmosensory signaling pathway	OBSOLETE. Catalysis of the phosphorylation and activation of a MAP kinase kinase (MAPKK), as part of a MAPK signaling cascade that passes on a signal within an osmosensory signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	MAPKKK activity involved in osmosensory signaling pathway|MAP kinase kinase kinase activity involved in osmosensory signalling pathway|MAP3K activity involved in osmosensory signaling pathway					This term has been obsoleted because it represents a GO-CAM model rather than a single GO term.		bf	2012-01-26T02:41:31Z		True			molecular_function											owl:Class	
GO:0051705	biolink:NamedThing	obsolete multi-organism behavior	OBSOLETE. Any process in which an organism has a behavioral effect on another organism of the same or different species.	tmpzr1t_l9r_go_relaxed.owl	behavioral interaction with other organism|behavioural interaction between organisms|behavioral interaction between organisms|behavioural interaction with other organism|behavioral signalling|behavioral signaling	https://github.com/geneontology/go-ontology/issues/18810				This term was obsoleted because it was an unnecessary grouping term.					True			biological_process											owl:Class	
GO:0017052	biolink:NamedThing	obsolete insulin-like growth factor binding protein	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	insulin-like growth factor binding protein					This term was made obsolete because it represents a single gene product and not a complex.	GO:0016942				True			cellular_component											owl:Class	
GO:0007471	biolink:NamedThing	obsolete prothoracic morphogenesis	OBSOLETE. The process by which the anatomical structures of the first or anterior segment of the insect thorax are generated and organized.	tmpzr1t_l9r_go_relaxed.owl	prothoracic morphogenesis					This term was made obsolete because it does not stipulate which anatomical part is involved in the process.	GO:0007470				True			biological_process											owl:Class	
GO:0110087	biolink:NamedThing	obsolete suppression by virus of host protease activator activity	OBSOLETE. Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host protease activator activity.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/22163				This term was obsoleted because it represents a molecular function.		kmv	2018-02-12T20:17:29Z		True			biological_process											owl:Class	
GO:0052395	biolink:NamedThing	obsolete induction by organism of defense-related symbiont nitric oxide production	OBSOLETE. The activation by an organism of the production of nitric oxide as part of the defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	activation by organism of defense-related symbiont nitric acid production|induction by organism of defense-related symbiont NO production|activation by organism of defense-related symbiont NO production|induction by organism of defense-related symbiont nitric oxide production					This term was made obsolete because it does not represent a real biological process.					True			biological_process											owl:Class	
GO:0052203	biolink:NamedThing	obsolete modulation of catalytic activity in other organism involved in symbiotic interaction	OBSOLETE. The process in which an organism effects a change in enzyme activity in a second organism, where the two organisms are in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	modulation of enzyme activity within other organism during symbiotic interaction	https://github.com/geneontology/go-ontology/issues/21740				This term was obsoleted because it represents an unnecessary grouping class.					True			biological_process											owl:Class	
GO:0051439	biolink:NamedThing	obsolete regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	OBSOLETE. A cell cycle process that modulates the frequency, rate or extent of ubiquitin ligase activity that contributes to the mitotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl	mitotic APC regulator|regulation of ubiquitin-protein ligase activity during mitotic cell cycle|regulation of ubiquitin ligase activity during mitotic cell cycle|mitotic anaphase-promoting complex regulator|mitotic ubiquitin-protein ligase regulator|mitotic SCF complex regulator|mitotic ubiquitin ligase regulator					false					True			biological_process											owl:Class	
GO:0001323	biolink:NamedThing	obsolete age-dependent general metabolic decline involved in chronological cell aging	OBSOLETE. A process of general metabolic decline that arises in non-dividing cells as they age, and alters cellular metabolism to cause a decline in cell function.	tmpzr1t_l9r_go_relaxed.owl	age-dependent general metabolic decline during chronological cell ageing|age-dependent general metabolic decline during chronological cell aging	https://github.com/geneontology/go-ontology/issues/18632				This term was obsoleted because it represent an assay - how long the cell lives -, not a true biological process.	GO:0044838|GO:0090398				True			biological_process											owl:Class	
GO:0016186	biolink:NamedThing	obsolete synaptic vesicle fission	OBSOLETE. Separation of a synaptic vesicle from the presynaptic membrane.	tmpzr1t_l9r_go_relaxed.owl	synaptic vesicle fission					This term was made obsolete because it was wrongly defined.	GO:0016192				True			biological_process											owl:Class	
GO:0039659	biolink:NamedThing	obsolete suppression by virus of host TBK1-IKBKE-DDX3 complex activity	OBSOLETE. Any process in which a virus stops, prevents, or reduces the activity of the host TBK1-IKBKE-DDX3 complex.	tmpzr1t_l9r_go_relaxed.owl	inhibition of host TBK1-IKBKE-DDX3 complex by virus|suppression by virus of host TBK1-IKKE-DDX3 complex activity				VZ:719	The reason for obsoleting this term is that it is too specific. The exact molecular roles of the individual proteins should be captured separately. See also: suppression by virus of host TBK1 activity; GO:0039723, and suppression by virus of host IKBKE activity; GO:0039724.		bf	2013-07-15T15:10:39Z		True			biological_process											owl:Class	
GO:0052339	biolink:NamedThing	obsolete disruption by organism of cell wall of other organism involved in symbiotic interaction	OBSOLETE. The chemical reactions and pathways performed by an organism resulting in the breakdown of the cell wall of a second organism, where the two organisms are in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	disassembly by organism of cell wall of other organism during symbiotic interaction					This term was obsoleted because it represents an unnecessary grouping class.					True			biological_process											owl:Class	
GO:1990982	biolink:NamedThing	obsolete Immune memory response	OBSOLETE. The immune response against a previously encountered antigen being quicker and quantitatively better compared with the primary response.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted at the TermGenie Gatekeeper stage.		sp	2016-09-01T10:57:56Z		True			biological_process											owl:Class	
GO:0075107	biolink:NamedThing	obsolete positive regulation by symbiont of host adenylate cyclase activity	OBSOLETE. Any process in which the symbiont activates, maintains or increases the frequency, rate or extent of the host adenylate cyclase activity, which involves catalysis of the reaction: ATP = 3',5'-cyclic AMP + diphosphate. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	positive regulation by symbiont of host ATP diphosphate-lyase (cyclizing ; 3',5'-cyclic-AMP-forming) activity|positive regulation by symbiont of host adenylyl cyclase activity|positive regulation by symbiont of host 3',5'-cyclic AMP synthetase activity|positive regulation by symbiont of host adenylylcyclase activity|positive regulation by symbiont of host adenyl cyclase activity	This term was obsoleted because it represents a molecular function.				This term was obsoleted because it represents a molecular function.					True			biological_process											owl:Class	
GO:0030528	biolink:NamedThing	obsolete transcription regulator activity	OBSOLETE. Plays a role in regulating transcription; may bind a promoter or enhancer DNA sequence or interact with a DNA-binding transcription factor.	tmpzr1t_l9r_go_relaxed.owl	transcriptional regulator activity|transcription regulator activity			GO:0140110		This term was obsoleted because it is essentially identical to a Process term (specifically the Biological Process term which has been selected as a term to consider for reannotation), i.e. it is defined only in terms of the process it acts in and it does NOT convey any information about the molecular nature of the function or whether the function is based on binding DNA, on interacting with other proteins, or some other mechanism. To transfer all annotations without review, the BP term indicated is considered to be equivalent and thus the only appropriate destination for all annotations. To reannotate to a MF term, you will probably need to revisit the original literature or other primary data because this "MF" term was not defined in terms of mechanism of action and there are multiple possibilities in the revised MF structure. In reannotation, please also consider descendent terms of the suggested MF terms as a more specific term may be more appropriate than the MF terms indicated. Please be aware that you may wish to request a new term if the mechanism of action of this gene product is not yet represented or if you are annotating for an RNAP different than one for which there is a specific suggested term. Also note that if there is no information about how the gene product acts, it may be appropriate to annotate to the root term for molecular_function.					True			molecular_function											owl:Class	
GO:0005357	biolink:NamedThing	obsolete constitutive glucose:proton symporter activity	OBSOLETE. Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucose + H+ = glucose + H+. This activity is constitutive and therefore always present, regardless of demand. Symporter activity enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported together in the same direction in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy.	tmpzr1t_l9r_go_relaxed.owl	constitutive hydrogen:glucose symporter activity|constitutive hydrogen:glucose transporter activity|constitutive hydrogen/glucose transporter activity					The reason for obsoletion is that the constitutive aspect of the transporter is unlikely to be an aspect of the activity, but instead it probably relates to the expression level of the transporter.					True			molecular_function											owl:Class	
GO:0010131	biolink:NamedThing	obsolete sucrose catabolic process, using invertase or sucrose synthase	OBSOLETE. The chemical reactions and pathways resulting in the breakdown of sucrose by the enzymatic action of either invertase or sucrose synthase.	tmpzr1t_l9r_go_relaxed.owl	sucrose breakdown, using invertase or sucrose synthase|sucrose degradation, using invertase or sucrose synthase|sucrose catabolism, using invertase or sucrose synthase|sucrose catabolic process, using invertase or sucrose synthase				MetaCyc:PWY-621|MetaCyc:PWY-3801	This term was made obsolete because it describes two different routes of sucrose catabolism, both of which are represented by molecular functions.	GO:0016157|GO:0004564|GO:0005987				True			biological_process											owl:Class	
GO:0008931	biolink:NamedThing	obsolete murein DD-endopeptidase activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	murein DD-endopeptidase activity			GO:0004252		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0061597	biolink:NamedThing	obsolete cyclic pyranopterin monophosphate synthase activity	OBSOLETE. Catalysis of the reaction GTP = cyclic pyranopterin phosphate + diphosphate.	tmpzr1t_l9r_go_relaxed.owl						This term was made obsolete because it represents two distinct molecular functions.		dph	2014-02-10T13:54:19Z		True			molecular_function											owl:Class	
GO:0052366	biolink:NamedThing	obsolete catabolism by organism of xylan in other organism involved in symbiotic interaction	OBSOLETE. The chemical reactions and pathways performed by an organism resulting in the breakdown of xylan within a second organism, where the two organisms are in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	catabolism by organism of xylan in other organism during symbiotic interaction	https://github.com/geneontology/go-ontology/issues/21396				This term was obsoleted because it represents an unnecessary grouping class.					True			biological_process											owl:Class	
GO:0005281	biolink:NamedThing	obsolete general amino acid permease activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	general amino acid permease activity|general amino acid transporter			GO:0015171		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0106194	biolink:NamedThing	obsolete translocase activity acting on inorganic cations and their chelates linked to a decarboxylation reaction	OBSOLETE. Catalysis of the transocation of inorganic cations and their chelates linked to a decarboxylation reaction.	tmpzr1t_l9r_go_relaxed.owl					EC:7.2.4.-	This term was made obsolete because the concept of using the non-4 digit EC classes as parent terms for the transporter banch of the onotolgy was consided confusing.		hjd	2019-05-08T16:58:50Z		True			molecular_function											owl:Class	
GO:1900532	biolink:NamedThing	obsolete negative regulation of cell proliferation involved in cellular hyperosmotic response	OBSOLETE. Negative regulation of cell proliferation during cellular hyperosmotic response.	tmpzr1t_l9r_go_relaxed.owl	down regulation of cell proliferation of cellular response to hypertonicity|down regulation of cell proliferation of cellular HOG response|inhibition of cell proliferation of cellular response to hypertonicity|down-regulation of cell proliferation of cellular response to hypertonicity|negative regulation of cell proliferation of cellular HOG response|downregulation of cell proliferation of cellular HOG response|negative regulation of cell proliferation of cellular response to hypertonicity|down regulation of cell proliferation of cellular hypertonic response|negative regulation of cell proliferation of cellular hypertonic response|inhibition of cell proliferation of cellular hypertonic response|negative regulation of cell proliferation involved in cellular hyperosmotic response|down-regulation of cell proliferation of cellular hypertonic response|down-regulation of cell proliferation of cellular HOG response|downregulation of cell proliferation of cellular response to hypertonicity|down regulation of cell proliferation of cellular hyperosmotic response|inhibition of cell proliferation of cellular HOG response|downregulation of cell proliferation of cellular hyperosmotic response|inhibition of cell proliferation of cellular hyperosmotic response|down-regulation of cell proliferation of cellular hyperosmotic response|downregulation of cell proliferation of cellular hypertonic response|negative regulation of cell proliferation of cellular hyperosmotic response					This term was obsoleted at the TermGenie Gatekeeper stage.		al	2012-05-08T02:42:52Z		True			biological_process											owl:Class	
GO:0005076	biolink:NamedThing	obsolete receptor signaling protein serine/threonine kinase signaling protein activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	receptor signaling protein serine/threonine kinase signaling protein activity|receptor signalling protein serine/threonine kinase signalling protein activity					This term was made obsolete because the meaning of the term is ambiguous and it incorporates process information.	GO:0035556				True			molecular_function											owl:Class	
GO:0009006	biolink:NamedThing	obsolete siroheme synthase activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	siroheme synthase activity|sirohaem synthase activity					This term was made obsolete because it represents three different molecular functions.	GO:0043115|GO:0051266|GO:0004851|GO:0019354				True			molecular_function											owl:Class	
GO:0075077	biolink:NamedThing	obsolete negative regulation by host of symbiont adenylate cyclase activity	OBSOLETE. Any process in which the host organism stops, prevents, or reduces the frequency, rate or extent of the symbiont adenylate cyclase activity, which catalyze the reaction: ATP = 3',5'-cyclic AMP + diphosphate. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl		This term was obsoleted because it represents a molecular function.				This term was obsoleted because it represents a molecular function.					True			biological_process											owl:Class	
GO:0019830	biolink:NamedThing	obsolete cadmium sensitivity/resistance	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	cadmium sensitivity/resistance			GO:0046686		This term was made obsolete because 'sensitivity/resistance' implies a phenotype rather than a biological process.					True			biological_process											owl:Class	
GO:0004245	biolink:NamedThing	obsolete neprilysin activity	OBSOLETE. Catalysis of the preferential cleavage at the amino group of hydrophobic residues in insulin, casein, hemoglobin, and a number of other proteins and polypeptides.	tmpzr1t_l9r_go_relaxed.owl	common acute lymphoblastic leukemia-associated antigens|kidney-brush-border neutral endopeptidase|neprilysin activity|CALLA (common acute lymphoblastic leukemia-associated) antigens|CALLA antigen|neutral endopeptidase activity|kidney-brush-border neutral peptidase|membrane metalloendopeptidase activity|common acute lymphoblastic leukemia antigen|kidney-brush-border neutral proteinase activity|neutral metallendopeptidase activity|CALLA glycoprotein|CD10|acute lymphoblastic leukemia antigen|CALLA glycoproteins|endopeptidase 24.11|CALLA|endopeptidase-2 activity|enkephalinase activity|neutral endopeptidase 24.11			GO:0004222		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0050749	biolink:NamedThing	obsolete apolipoprotein E receptor binding	OBSOLETE. Interacting selectively with an apolipoprotein E receptor.	tmpzr1t_l9r_go_relaxed.owl	apolipoprotein E receptor binding			GO:0070326		This term was made obsolete because no known receptor binds apolipoprotein E; instead, receptors bind holo-lipoprotein E (apolipoprotein E + bound lipid).					True			molecular_function											owl:Class	
GO:0052554	biolink:NamedThing	obsolete modulation by organism of symbiont immune response	OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of the immune response of the symbiont organism; the immune response is any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	modulation by organism of symbiont immune response					This term was made obsolete because it does not represent a real biological process.					True			biological_process											owl:Class	
GO:0015428	biolink:NamedThing	obsolete type I protein secretor activity	OBSOLETE. This term was not defined before being made obsolete.	tmpzr1t_l9r_go_relaxed.owl	type I protein secretor activity					This term was made obsolete because it does not accurately reflect the function of the proteins involved.					True			molecular_function											owl:Class	
GO:0005561	biolink:NamedThing	obsolete nucleic acid	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	nucleic acid					Note that this term was deleted from GO and was restored to the ontology in Feb 2003 to ensure that the ID is not reused.					True			cellular_component											owl:Class	
GO:0023009	biolink:NamedThing	obsolete initiation of T cell receptor signaling	OBSOLETE. The process in which a signal causes activation of T cell receptor signaling.	tmpzr1t_l9r_go_relaxed.owl	initiation of T cell receptor signalling|initiation of T cell receptor signaling					This term was made obsolete because the meaning of the term is ambiguous.	GO:0042101|GO:0038023|GO:0048018|GO:0050852		2010-02-16T09:30:50Z		True			biological_process											owl:Class	
GO:0100058	biolink:NamedThing	obsolete positive regulation of phenotypic switching by transcription from RNA polymerase II promoter	OBSOLETE. Any transcription from RNA polymerase II promoter process that positively regulates phenotypic switching.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it represents a GO-CAM model.		cjm	2015-04-02T04:13:19Z		True			biological_process											owl:Class	
GO:0052453	biolink:NamedThing	obsolete modulation by organism of symbiont intracellular transport	OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of the directed movement of substances within the cell or cells of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	modulation by organism of symbiont intracellular transport|modulation of symbiont intracellular trafficking					This term was made obsolete because it does not represent a real biological process.					True			biological_process											owl:Class	
GO:0006889	biolink:NamedThing	obsolete regulation of calcium in ER	OBSOLETE. Any process that modulates the concentration of calcium in the endoplasmic reticulum.	tmpzr1t_l9r_go_relaxed.owl	regulation of calcium in ER					This term was made obsolete because the term name is ambiguous and as a result, the term was incorrectly placed in the ontology (it was a descendant of 'protein transport').	GO:0006874|GO:0005783				True			biological_process											owl:Class	
GO:1905112	biolink:NamedThing	obsolete regulation of centromere clustering at the mitotic nuclear envelope	OBSOLETE. Any process that modulates the frequency, rate or extent of centromere clustering at the nuclear envelope.	tmpzr1t_l9r_go_relaxed.owl	regulation of kinetochore clustering at spindle pole body|regulation of centromere clustering at the nuclear periphery|regulation of kinetochore clustering at SPB|regulation of kinetochore clustering at the old mitotic spindle pole body|regulation of kinetochore localization at spindle pole body|regulation of rabl configuration|regulation of centromere-SPB clustering					This term was obsoleted because it represented a phenotype.		al	2016-04-06T16:25:41Z		True			biological_process											owl:Class	
GO:1990057	biolink:NamedThing	obsolete cell cycle arrest in response to DNA damage stimulus	OBSOLETE. The cell cycle regulatory process in which the cell cycle is halted during one of the normal phases (G1, S, G2, M) as a result of DNA damage from environmental insults or errors during metabolism.	tmpzr1t_l9r_go_relaxed.owl	cell cycle arrest in response to DNA damage stimulus					This term was obsoleted at the TermGenie Gatekeeper stage.		rph	2013-03-06T13:48:44Z		True			biological_process											owl:Class	
GO:0035536	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052212	biolink:NamedThing	obsolete modification of morphology or physiology of other organism via secreted substance involved in symbiotic interaction	OBSOLETE. The process in which an organism effects a change in the structure or function of a second organism, mediated by a substance secreted by one of the organisms, where the two organisms are in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	modification of host morphology or physiology via effector molecule|modification of morphology or physiology of other organism via secreted substance during symbiotic interaction|modification of host morphology or physiology via ellicitor					This term was obsoleted because it conflated the process in which a gene product is involved with the secretion system by which it reaches its target.					True			biological_process											owl:Class	
GO:0015223	biolink:NamedThing	obsolete vitamin or cofactor transporter activity	OBSOLETE. Enables the directed transport of vitamins or cofactors into, out of or within a cell, or between cells.	tmpzr1t_l9r_go_relaxed.owl	vitamin or cofactor transporter activity|vitamin/cofactor transporter activity					This term was made obsolete because it was replaced by more specific terms.	GO:0090482				True			molecular_function											owl:Class	
GO:0061424	biolink:NamedThing	obsolete positive regulation of peroxisome organization by positive regulation of transcription from RNA polymerase II promoter	OBSOLETE. Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter and activates or increases the frequency, rate or extent of peroxisome organization.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of peroxisome organisation by positive regulation of transcription from RNA polymerase II promoter					This term was obsoleted because it represents a GO-CAM model.		dph	2012-02-02T12:50:36Z		True			biological_process											owl:Class	
GO:0008947	biolink:NamedThing	obsolete omptin activity	OBSOLETE. Catalysis of the preferential cleavage of Xaa-Yaa in which both Xaa and Yaa are Arg or Lys.	tmpzr1t_l9r_go_relaxed.owl	omptin activity			GO:0004252		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0075230	biolink:NamedThing	obsolete spore movement on or near host	OBSOLETE. Any process involved in the directed movement of a motile spore on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it represented both a process and a location.					True			biological_process											owl:Class	
GO:0052448	biolink:NamedThing	obsolete modulation by organism of ethylene levels in symbiont	OBSOLETE. The alteration by an organism of the levels of ethylene in the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	modulation by organism of ethylene levels in symbiont					This term was made obsolete because it does not represent a real biological process.					True			biological_process											owl:Class	
GO:0097605	biolink:NamedThing	obsolete regulation of nuclear envelope permeability	OBSOLETE. Any process that modulates the frequency, rate or extent of the passage or uptake of molecules by the nuclear envelope.	tmpzr1t_l9r_go_relaxed.owl	regulation of nuclear membrane permeability					The reason for obsoletion is that the nuclear envelope is quite permeable, so there is no cellular process to regulate it.		pr	2014-05-14T15:41:44Z		True			biological_process											owl:Class	
results_in_morphogenesis_of	biolink:NamedThing	results in morphogenesis of		tmpzr1t_l9r_go_relaxed.owl					RO:0002298									external									results_in_morphogenesis_of			
GO:0046264	biolink:NamedThing	obsolete thiocyanate biosynthetic process	OBSOLETE. The chemical reactions and pathways resulting in the formation of thiocyanate, any anion or salt of thiocyanic acid.	tmpzr1t_l9r_go_relaxed.owl	thiocyanate biosynthetic process|thiocyanate synthesis|thiocyanate biosynthesis|thiocyanate anabolism|thiocyanate formation			GO:0018969		This term was made obsolete because thiocyanates are not synthesized by living organisms, and GO does not cover non-biological processes.					True			biological_process											owl:Class	
GO:0000186	biolink:NamedThing	obsolete activation of MAPKK activity	OBSOLETE. The initiation of the activity of the inactive enzyme MAP kinase kinase (MAPKK).	tmpzr1t_l9r_go_relaxed.owl	activation of MAP/ERK kinase kinase|positive regulation of MAPKK activity|activation of MAPKK activity during sporulation|activation of MAP kinase kinase activity|activation of MAP2K activity	https://github.com/geneontology/go-ontology/issues/21307				This term was obsoleted because it represents a molecular function.	GO:0043539|GO:0000165				True			biological_process											owl:Class	
GO:0003082	biolink:NamedThing	obsolete positive regulation of renal output by angiotensin	OBSOLETE. Any process in which angiotensin directly increases the rate of natriuresis and diuresis in the kidney.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of renal output by angiotensin|angiotensin mediated positive regulation of renal output|angiotensin-mediated positive regulation of renal output					This term was made obsolete because the term is misleading.					True			biological_process											owl:Class	
GO:0033706	biolink:NamedThing	obsolete quinate/shikimate dehydrogenase activity	OBSOLETE. Catalysis of the reactions: L-quinate + NAD(P)+ = 3-dehydroquinate + NAD(P)H + H+, and shikimate + NAD(P)+ = 3-dehydroshikimate + NAD(P)H + H+.	tmpzr1t_l9r_go_relaxed.owl	YdiB|L-quinate:NAD(P)+ 3-oxidoreductase activity|quinate/shikimate dehydrogenase activity					This term was made obsolete because it represents four reactions, and should be four separate terms.	GO:0052733|GO:0004764|GO:0030266|GO:0052734				True			molecular_function											owl:Class	
GO:0016527	biolink:NamedThing	obsolete brain-specific angiogenesis inhibitor activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	brain-specific angiogenesis inhibitor activity					This term was made obsolete because it is based on anatomical information, and describes at least one gene product. It has also never been defined.	GO:0004930				True			molecular_function											owl:Class	
GO:0046800	biolink:NamedThing	obsolete enhancement of virulence	OBSOLETE. Any process that activates or increases the severity of viral infection and subsequent disease.	tmpzr1t_l9r_go_relaxed.owl	enhancement of virulence					This term was made obsolete because 'virulence' is not a biological process; however, alteration of virulence also does not fit under 'regulation of biological quality ; GO:0065008' because it is a product both of the genotype/phenotype of the infecting organism and the genotype/phenotype of the organism being infected and varies by individual within a species both for the infecting organism and the infected organism.					True			biological_process											owl:Class	
GO:1902188	biolink:NamedThing	obsolete positive regulation of viral release from host cell	OBSOLETE. Any process that activates or increases the frequency, rate or extent of viral release from host cell.	tmpzr1t_l9r_go_relaxed.owl	up regulation of viral shedding|up-regulation of viral exit|upregulation of release of virus from host|positive regulation of viral release|activation of viral release|activation of viral exit|positive regulation of viral exit|up regulation of viral release from host cell|activation of viral shedding|positive regulation of release of virus from host|upregulation of viral release from host cell|activation of release of virus from host|up regulation of release of virus from host|up-regulation of viral release|upregulation of viral shedding|up regulation of viral release|upregulation of viral exit|positive regulation of viral shedding|up regulation of viral exit|activation of viral release from host cell|upregulation of viral release|up-regulation of viral release from host cell|up-regulation of release of virus from host|up-regulation of viral shedding	https://github.com/geneontology/go-ontology/issues/22168		GO:0019076		This term was obsoleted because there is no evidence that it is a regulated process.		ss	2013-06-04T03:54:14Z		True			biological_process											owl:Class	
GO:0016816	biolink:NamedThing	obsolete hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in other compounds	OBSOLETE. Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in substances other than amides, amidines and nitriles.	tmpzr1t_l9r_go_relaxed.owl	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in other compounds					This term was made obsolete because it was an unnecessary grouping term.	GO:0016810				True			molecular_function											owl:Class	
GO:0016356	biolink:NamedThing	obsolete organophosphorus susceptibility/resistance	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	organophosphorus susceptibility/resistance			GO:0046683		This term was made obsolete because 'susceptibility/resistance' implies a phenotype rather than a biological process.					True			biological_process											owl:Class	
GO:0017120	biolink:NamedThing	obsolete polyphosphatidylinositol phosphatase activity	OBSOLETE. Catalysis of the conversion of phosphatidylinositol-3-phosphate, phosphatidylinositol-4-phosphate, and phosphatidylinositol-3,5-bisphosphate, but not PI-4,5-bisphosphate, to phosphatidylinositol; PPIPase activity is a key regulator of membrane trafficking and actin cytoskeleton organization.	tmpzr1t_l9r_go_relaxed.owl	polyphosphoinositide phosphatase activity|polyphosphatidylinositol phosphatase activity					This term was made obsolete because it represents a gene product.	GO:0004438|GO:0034593|GO:0043812				True			molecular_function											owl:Class	
GO:0039578	biolink:NamedThing	obsolete suppression by virus of host JAK1 activity via JAK1 binding	OBSOLETE.  Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host JAK1 (Janus Kinase 1) activity by interacting directly and selectively with JAK1. For example, the polyoma virus T antigen binds to JAK1 and renders it inactive.	tmpzr1t_l9r_go_relaxed.owl						The reason for obsoleting this term is that it is too specific. The exact molecular roles of the individual proteins should be captured separately.		bf			True			biological_process											owl:Class	
GO:0030105	biolink:NamedThing	obsolete anaphylaxis	OBSOLETE. Extreme immunological sensitivity of the body or tissues to the reintroduction of an antigen. It is a form of anamnestic reaction and is accompanied by pathological changes in tissues or organs due to the release of pharmacologically active substances.	tmpzr1t_l9r_go_relaxed.owl	anaphylaxis					This term was made obsolete because it represents a an abnormal process that is harmful to the organism.	GO:0006955				True			biological_process											owl:Class	
GO:0043902	biolink:NamedThing	obsolete positive regulation of multi-organism process	OBSOLETE. Any process that activates or increases the frequency, rate or extent of a multi-organism process, a process in which an organism has an effect on another organism of the same or different species.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it is an unnecessary grouping term.					True			biological_process											owl:Class	
GO:0098504	biolink:NamedThing	obsolete DNA 3' dephosphorylation involved in DNA repair	OBSOLETE. Any 3' DNA dephosphorylation that is involved in the process of DNA repair.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it represents a molecular function, and not a specific coordinated process.		dos	2013-09-18T14:52:15Z		True			biological_process											owl:Class	
GO:0051442	biolink:NamedThing	obsolete negative regulation of ubiquitin-protein ligase activity involved in meiotic cell cycle	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of ubiquitin ligase activity during the meiotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl	meiotic anaphase-promoting complex inhibitor|meiotic SCF complex inhibitor|meiotic APC inhibitor|meiotic anaphase promoting complex inhibitor|anaphase promoting complex inhibition during meiotic cell cycle|down regulation of ubiquitin ligase activity during meiotic cell cycle|meiotic APC inhibition|inhibition of ubiquitin ligase activity during meiotic cell cycle|anaphase-promoting complex inhibition during meiotic cell cycle|meiotic anaphase promoting complex inhibition|downregulation of ubiquitin ligase activity during meiotic cell cycle|negative regulation of ubiquitin ligase activity during meiotic cell cycle|meiotic ubiquitin ligase inhibitor|APC inhibition during meiotic cell cycle|down-regulation of ubiquitin ligase activity during meiotic cell cycle|meiotic anaphase-promoting complex inhibition	https://github.com/geneontology/go-ontology/issues/15196				This term was obsoleted because it should be captured as a GO-CAM model.					True			biological_process											owl:Class	
GO:1990870	biolink:NamedThing	obsolete protein fibril	OBSOLETE. A polymer of proteins that form a fine fiber.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted at the TermGenie Gatekeeper stage.		sl	2015-09-25T17:05:32Z		True			cellular_component											owl:Class	
GO:0016919	biolink:NamedThing	obsolete nardilysin activity	OBSOLETE. Catalysis of the hydrolysis of polypeptides, preferably at the first bond of Xaa-Arg-Lys, and less commonly at the first bond of Arg-Arg-Xaa, in which Xaa is not Arg or Lys.	tmpzr1t_l9r_go_relaxed.owl	NRD convertase activity|nardilysin activity|N-arginine dibasic convertase activity|NRD-convertase activity			GO:0004222		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0004005	biolink:NamedThing	obsolete plasma membrane cation-transporting ATPase	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	plasma membrane cation-transporting ATPase					This term was made obsolete because it contains both component and function information.	GO:0019829|GO:0005886				True			molecular_function											owl:Class	
GO:0001026	biolink:NamedThing	obsolete TFIIIB-type transcription factor activity	OBSOLETE. Binding to an RNA polymerase III (Pol III) complex, typically composed of seventeen subunits, and with another protein, macromolecule, or complex, permitting those molecules to function in a coordinated way, Once recruited to an RNA polymerase III promoter by one or more other transcription factors, binds to DNA, recruits RNA polymerase III and facilitates the transition from the closed to the open complex.	tmpzr1t_l9r_go_relaxed.owl	RNA polymerase III recruiting transcription factor activity					This term was obsoleted because it represents a gene product.		krc	2010-08-23T12:24:31Z		True			molecular_function											owl:Class	
GO:0072427	biolink:NamedThing	obsolete detection of DNA damage stimulus involved in intra-S DNA damage checkpoint	OBSOLETE. The series of events in which information about damage to DNA is received and converted into a molecular signal, contributing to an intra-S DNA damage checkpoint.	tmpzr1t_l9r_go_relaxed.owl	intra-S DNA damage checkpoint sensor mechanism|intra-S DNA damage checkpoint sensor process|sensing involved in intra-S DNA damage checkpoint	https://github.com/geneontology/go-ontology/issues/20976				This term was obsoleted because it corresponds to a molecular function.		mah	2010-12-08T04:30:27Z		True			biological_process											owl:Class	
GO:0015933	biolink:NamedThing	obsolete flavin-containing electron transporter	OBSOLETE. An oxidoreductase which contains either flavin-adenine dinucleotide or flavin mononucleotide as a prosthetic group, utilizes either NADH or NADPH and transfers electrons to other electron transfer proteins.	tmpzr1t_l9r_go_relaxed.owl	flavin-containing electron transporter			GO:0009055		This term was made obsolete because it does not describe a molecular function.					True			molecular_function											owl:Class	
GO:0010538	biolink:NamedThing	obsolete Hsp27 protein regulator activity	OBSOLETE. Modulates the activity of the Hsp27 molecular chaperone.	tmpzr1t_l9r_go_relaxed.owl	Hsp27 protein regulator activity			GO:0051008		This term was made obsolete because it refers to a non-existent molecular function term, 'Hsp27 protein activity'.	GO:0051082|GO:0006457|GO:0051787				True			molecular_function											owl:Class	
GO:0015352	biolink:NamedThing	obsolete secondary active sterol transmembrane transporter activity	OBSOLETE. Enables the transfer of sterol from one side of a membrane to the other, up the solute's concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction.	tmpzr1t_l9r_go_relaxed.owl	sterol porter activity					This term was obsoleted because there is no evidence that this function exists.					True			molecular_function											owl:Class	
GO:0030180	biolink:NamedThing	obsolete solute:solute exchange	OBSOLETE. Exchange diffusion of two solutes between the inside and outside of a cell or subcellular compartment, in which movement of one solute down a concentration gradient drives movement of the other solute in the opposite direction.	tmpzr1t_l9r_go_relaxed.owl	solute:solute exchange					This term was made obsolete because it represents a molecular function.	GO:0015297|GO:0006810				True			biological_process											owl:Class	
GO:0051399	biolink:NamedThing	obsolete N-terminal arginine aminopeptidase activity	OBSOLETE. Catalysis of the hydrolysis of an arginine residue from the N-terminal of an oligopeptide or polypeptide chain.	tmpzr1t_l9r_go_relaxed.owl	N-terminal arginine aminopeptidase activity|argininyl aminopeptidase activity|arginine aminopeptidase activity			GO:0004177		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:1903239	biolink:NamedThing	obsolete regulation of positive regulation of the force of heart contraction by chemical signal	OBSOLETE. Any process that modulates the frequency, rate or extent of positive regulation of the force of heart contraction by chemical signal.	tmpzr1t_l9r_go_relaxed.owl	regulation of positive regulation of the force of heart muscle contraction by chemical signal|regulation of positive regulation of the force of heart contraction by chemical signal					This term was obsoleted at the TermGenie Gatekeeper stage.		rl	2014-07-31T17:00:17Z		True			biological_process											owl:Class	
GO:1900427	biolink:NamedThing	obsolete regulation of cellular response to oxidative stress by regulation of transcription from RNA polymerase II promoter	OBSOLETE. A regulation of transcription from RNA polymerase II promoter that results in regulation of cellular response to oxidative stress.	tmpzr1t_l9r_go_relaxed.owl	regulation of adaptive response to oxidative stress by regulation of transcription from RNA polymerase II promoter					This term was obsoleted because it represents a GO-CAM model.		mah	2012-04-25T09:11:41Z		True			biological_process											owl:Class	
GO:0018331	biolink:NamedThing	obsolete enzyme active site formation via O-phospho-L-serine	OBSOLETE. The transient phosphorylation of peptidyl-serine to form O-phospho-L-serine.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/15594			RESID:AA0037	This term was obsoleted because it represents a reaction intermediate, not a biological process, see PMID:8061611 and PMID:12923550.					True			biological_process											owl:Class	
GO:1900007	biolink:NamedThing	obsolete regulation of extrachromosomal rDNA circle accumulation involved in replicative cell aging	OBSOLETE. Any process that modulates the frequency, rate or extent of extrachromosomal rDNA circle accumulation involved in replicative cell aging.	tmpzr1t_l9r_go_relaxed.owl	regulation of extrachromosomal rDNA circle accumulation during replicative cell aging|regulation of extrachromosomal rDNA circle accumulation during replicative cell ageing|regulation of extrachromosomal ribosomal DNA circle accumulation during replicative cell aging	https://github.com/geneontology/go-ontology/issues/20007				This term was obsoleted because it represents an assay, not a true biological process.		se	2012-01-09T10:44:07Z		True			biological_process											owl:Class	
RO:0002588	biolink:NamedThing	results_in_assembly_of		tmpzr1t_l9r_go_relaxed.owl					RO:0002588									external									results_in_assembly_of			
GO:0052138	biolink:NamedThing	obsolete aerotaxis on or near host	OBSOLETE. The movement of a motile cell or organism in response to environmental oxygen on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/18819				This term was obsoleted because it represents both a process and a location.					True			biological_process											owl:Class	
GO:0023037	biolink:NamedThing	obsolete signal initiation by light	OBSOLETE. The process in which a light signal causes activation of a receptor.	tmpzr1t_l9r_go_relaxed.owl	signal initiation by light					This term was made obsolete because the meaning of the term is ambiguous.	GO:0010161|GO:0010017|GO:0009785|GO:0010018|GO:0009881		2010-02-16T09:30:50Z		True			biological_process											owl:Class	
GO:0035625	biolink:NamedThing	obsolete epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway	OBSOLETE. The process in which an epidermal growth factor-activated receptor is activated via signaling events from a consequence of a G protein-coupled . This is an example of cross-talk between the EGF and GPCR signaling pathways.	tmpzr1t_l9r_go_relaxed.owl	EGFR transactivation upon GPCR stimulation|EGFR transactivation by GPCR|epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signalling pathway|epidermal growth factor receptor transactivation by G-protein coupled receptor signaling pathway	https://github.com/geneontology/go-ontology/issues/15823				This term was obsoleted because it should be captured as a GO-CAM model.		bf	2010-12-08T04:19:12Z		True			biological_process											owl:Class	
GO:0006343	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0006389	biolink:NamedThing	obsolete tRNA-Y splicing	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	tRNA-Y splicing					This term was made obsolete because it does not represent a process unique to splicing of the tyrosyl (Y) tRNA.	GO:0006388				True			biological_process											owl:Class	
GO:0075074	biolink:NamedThing	obsolete spore autophagy involved in appressorium formation on or near host	OBSOLETE. The process in which a symbiont spore digests parts of its own cytoplasm, occurring when the appressorium forms on or near the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	spore autophagy during appressorium formation on or near host|autophagy of spores during appressorium formation on or near host					The reason for obsoletion is that this term did not represent any specific host/symbiont process.					True			biological_process											owl:Class	
GO:0005377	biolink:NamedThing	obsolete intracellular copper ion transporter	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	intracellular copper ion transporter|intracellular copper transporter					This term was made obsolete because it contains both component and function information.	GO:0005622|GO:0005375				True			molecular_function											owl:Class	
GO:0035558	biolink:NamedThing	obsolete phosphatidylinositol 3-kinase cascade involved in insulin receptor signaling	OBSOLETE. The process in which a signal is passed from the insulin receptor to components of the phosphatidylinositol 3-kinase (PI3K) cascade, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell.	tmpzr1t_l9r_go_relaxed.owl	phosphoinositide 3-kinase cascade involved in insulin receptor signalling|phosphoinositide 3-kinase cascade involved in insulin receptor signaling|PI3K cascade involved in signaling from the insulin receptor|phosphatidylinositol 3-kinase cascade involved in insulin receptor signaling|phosphatidylinositol 3-kinase cascade involved in insulin receptor signalling					This term was made obsolete because the syntax of the term is incorrect.	GO:0038028	bf	2010-05-14T01:34:38Z		True			biological_process											owl:Class	
GO:0044118	biolink:NamedThing	obsolete development of symbiont in host cell	OBSOLETE. The progression of the symbiont from an initial condition to a later condition, occurring in its host's cell. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/20305				This term was obsoleted because it represents both a process and a location.		jl	2009-07-30T03:52:00Z		True			biological_process											owl:Class	
GO:0017139	biolink:NamedThing	obsolete arsenate sensitivity/resistance	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	arsenate sensitivity/resistance			GO:0046685		This term was made obsolete because 'sensitivity/resistance' implies a phenotype rather than a biological process.					True			biological_process											owl:Class	
GO:0000991	biolink:NamedThing	obsolete transcription factor activity, core RNA polymerase II binding	OBSOLETE. Binding to an RNA polymerase II (Pol II) complex, typically composed of twelve subunits, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well.	tmpzr1t_l9r_go_relaxed.owl	core RNA polymerase II binding transcription factor activity	https://github.com/geneontology/go-ontology/issues/16053				The reason for obsoletion is that this concept is partly covered by other concepts in the ontology and usage has been inconsistent.	GO:0140110|GO:0000993	krc	2010-08-10T05:03:45Z		True			molecular_function											owl:Class	
GO:0061401	biolink:NamedThing	obsolete positive regulation of transcription from RNA polymerase II promoter in response to a hypotonic environment	OBSOLETE. Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of detection of, or exposure to, a decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/12739				This term was obsoleted because it represents a GO-CAM model.	GO:0045944|GO:0071476	dph	2012-01-10T09:43:08Z		True			biological_process											owl:Class	
GO:1902539	biolink:NamedThing	obsolete multi-organism macropinocytosis	OBSOLETE. A macropinocytosis which involves another organism.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/21459				This term was obsoleted because there is no evidence that this process exists.		jl	2013-12-02T14:23:06Z		True			biological_process											owl:Class	
GO:0000197	biolink:NamedThing	obsolete activation of MAPKKK activity involved in cell wall organization or biogenesis	OBSOLETE. Any process that initiates the activity of the inactive enzyme MAP kinase kinase kinase in the context of cell wall organization or biogenesis.	tmpzr1t_l9r_go_relaxed.owl	activation of MAPKKK activity involved in cell wall biogenesis|activation of MAP kinase kinase kinase activity during cell wall biogenesis|cell wall biogenesis, activation of MAP kinase kinase kinase activity|cell wall biogenesis, activation of MAPKKK activity|activation of MAPKKK activity involved in cell wall integrity	https://github.com/geneontology/go-ontology/issues/20242				This term was obsoleted because it represents a GO-CAM model.	GO:0043539|GO:0000165				True			biological_process											owl:Class	
GO:0048503	biolink:NamedThing	obsolete GPI anchor binding	OBSOLETE. Interacting selectively with any glycosylphosphatidylinositol anchor. GPI anchors serve to attach membrane proteins to the lipid bilayer of cell membranes.	tmpzr1t_l9r_go_relaxed.owl	GPI anchor binding|glycosylphosphatidylinositol binding					This term was made obsolete because it has been widely, and incorrectly, used to annotate proteins that have GPI anchors covalently attached. A new term has been created that can be used to annotate gene products that interact non-covalently with GPI anchors.					True			molecular_function											owl:Class	
GO:1900530	biolink:NamedThing	obsolete regulation of cell shape involved in cellular response to salt stress	OBSOLETE. Any regulation of cell shape that is involved in cellular response to salt stress.	tmpzr1t_l9r_go_relaxed.owl	regulation of cell shape of cellular salinity response|regulation of cell shape of cellular response to salt stress|regulation of cell shape of cellular response to ionic osmotic stress|regulation of cell shape involved in cellular response to salt stress					This term was obsoleted at the TermGenie Gatekeeper stage.		al	2012-05-08T01:48:01Z		True			biological_process											owl:Class	
OIO:hasRelatedSynonym	biolink:NamedThing	has_related_synonym		tmpzr1t_l9r_go_relaxed.owl																									owl:AnnotationProperty	
GO:0008711	biolink:NamedThing	obsolete ADP-L-glycero-D-manno-heptose synthase activity	OBSOLETE. This term was not defined before being made obsolete.	tmpzr1t_l9r_go_relaxed.owl	ADP-L-glycero-D-manno-heptose synthase activity					This term was made obsolete because it represents a bifunctional gene product (e.g. E. coli RfaE).	GO:0033786|GO:0033785				True			molecular_function											owl:Class	
GO:0004200	biolink:NamedThing	obsolete signaling (initiator) caspase activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	signaling (initiator) caspase activity|signalling (initiator) caspase activity			GO:0004197		This term was made obsolete because it includes biological process information.	GO:0006915				True			molecular_function											owl:Class	
GO:0005322	biolink:NamedThing	obsolete low-density lipoprotein	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	low-density lipoprotein|LDL			GO:0005319		This term was made obsolete because it does not represent a molecular function.					True			molecular_function											owl:Class	
GO:1990980	biolink:NamedThing	obsolete copper ion transport across blood-CSF barrier	OBSOLETE. The directed movement of copper ions passing through the blood-cerebrospinal fluid barrier.	tmpzr1t_l9r_go_relaxed.owl	copper ion transport across BCB|copper ion transport across blood-cerebrospinal fluid barrier					This term was obsoleted at the TermGenie Gatekeeper stage.		sl	2016-08-17T21:14:18Z		True			biological_process											owl:Class	
GO:0072436	biolink:NamedThing	obsolete detection of stimulus involved in DNA replication checkpoint	OBSOLETE. The series of events in which information about whether DNA replication is complete is received and converted into a molecular signal, contributing to a DNA replication checkpoint.	tmpzr1t_l9r_go_relaxed.owl	DNA replication checkpoint sensor mechanism|sensing involved in DNA replication checkpoint|DNA replication checkpoint sensor process	https://github.com/geneontology/go-ontology/issues/20976				This term was obsoleted because it corresponds to a molecular function.		mah	2010-12-08T04:52:09Z		True			biological_process											owl:Class	
GO:0030227	biolink:NamedThing	obsolete apolipoprotein E receptor activity	OBSOLETE. Combining with apolipoprotein E to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	ApoE receptor|apolipoprotein E receptor activity			GO:0030229		This term was made obsolete because no known receptor binds apolipoprotein E; instead, receptors bind holo-lipoprotein E (apolipoprotein E + bound lipid).					True			molecular_function											owl:Class	
GO:0046257	biolink:NamedThing	obsolete anaerobic 2,4,6-trinitrotoluene biosynthetic process	OBSOLETE. The chemical reactions and pathways resulting in the formation of 2,4,6-trinitrotoluene, 1-methyl-2,4,6-trinitrobenzene, a highly explosive pale yellow crystalline solid, in the absence of oxygen.	tmpzr1t_l9r_go_relaxed.owl	anaerobic 2,4,6-trinitrotoluene biosynthetic process|anaerobic 2,4,6-trinitrotoluene biosynthesis|anaerobic 2,4,6-trinitrotoluene formation|anaerobic 2,4,6-trinitrotoluene synthesis|anaerobic 2,4,6-trinitrotoluene anabolism			GO:0018975		This term was made obsolete because 2,4,6-trinitrotoluene is not synthesized by living organisms, and GO does not cover non-biological processes.					True			biological_process											owl:Class	
GO:0015600	biolink:NamedThing	obsolete glutamate/aspartate porter activity	OBSOLETE. Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + polar amino acid(out) = ADP + phosphate + polar amino acid(in).	tmpzr1t_l9r_go_relaxed.owl	glutamate/aspartate porter activity					This term was made obsolete because it represents a multifunctional gene product.	GO:0015183|GO:0005313|GO:0015426				True			molecular_function											owl:Class	
GO:0051801	biolink:NamedThing	obsolete cytolysis in other organism involved in symbiotic interaction	OBSOLETE. The killing by an organism of a cell in a second organism by means of the rupture of cell membranes and the loss of cytoplasm, where the two organisms are in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	cytolysis of cells in other organism during symbiotic interaction|cytolysis of cells in other organism involved in symbiotic interaction					This term was obsoleted because it represents an unnecessary grouping class.					True			biological_process											owl:Class	
GO:1902718	biolink:NamedThing	obsolete sequestering of copper ion	OBSOLETE. Any process that modulates the frequency, rate or extent of sequestering of copper ion.	tmpzr1t_l9r_go_relaxed.owl	sequestering of copper ion					This term was obsoleted at the TermGenie Gatekeeper stage.		mr	2014-02-24T16:08:53Z		True			biological_process											owl:Class	
GO:0052457	biolink:NamedThing	obsolete modulation by organism of defense-related symbiont nitric oxide production	OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of the production of nitric oxide as part of the defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	modulation by organism of defense-related symbiont nitric oxide production|modulation by organism of defense-related symbiont NO production					This term was made obsolete because it does not represent a real biological process.					True			biological_process											owl:Class	
GO:1902535	biolink:NamedThing	obsolete multi-organism membrane invagination	OBSOLETE. A membrane invagination which involves another organism.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/21459				This term was obsoleted because there is no evidence that this process exists.		jl	2013-12-02T13:58:43Z		True			biological_process											owl:Class	
GO:0035968	biolink:NamedThing	obsolete regulation of sterol import by regulation of transcription from RNA polymerase II promoter	OBSOLETE. Any process that modulates the frequency, rate or extent of sterol import, by regulation of transcription from an RNA polymerase II promoter.	tmpzr1t_l9r_go_relaxed.owl	regulation of sterol import by regulation of transcription from Pol II promoter|regulation of sterol uptake by regulation of transcription from Pol II promoter|regulation of sterol uptake by regulation of transcription from RNA polymerase II promoter|regulation of sterol influx by regulation of transcription from Pol II promoter|regulation of sterol influx by regulation of transcription from RNA polymerase II promoter					This term was obsoleted because it represents a GO-CAM model.		bf			True			biological_process											owl:Class	
GO:0009476	biolink:NamedThing	obsolete class IV cytochrome c	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	class IV cytochrome c					This term was made obsolete because it represents a gene product.	GO:0009055				True			molecular_function											owl:Class	
RO:0002224	biolink:NamedThing	starts with		tmpzr1t_l9r_go_relaxed.owl					RO:0002224									external									starts_with			
GO:0003078	biolink:NamedThing	obsolete regulation of natriuresis	OBSOLETE. Any process that modulates the frequency, rate, or extent of natriuresis, the process of renal sodium excretion.	tmpzr1t_l9r_go_relaxed.owl	regulation of natriuresis					This term was made obsolete because its definition was inaccurate.	GO:0035813				True			biological_process											owl:Class	
GO:0009473	biolink:NamedThing	obsolete cytochrome c7 (triheme)	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	cytochrome c7 (triheme)					This term was made obsolete because it represents a gene product.	GO:0009055				True			molecular_function											owl:Class	
GO:0035656	biolink:NamedThing	obsolete kinesin-associated melanosomal adaptor activity	OBSOLETE. The activity of linking kinesins, cytoplasmic proteins responsible for moving vesicles and organelles towards the distal end of microtubules, to melanosomes.	tmpzr1t_l9r_go_relaxed.owl	kinesin-melanosome adaptor activity	https://github.com/geneontology/go-ontology/issues/17668				This term was obsoleted because it represents the function of a specific protein.	GO:0030674|GO:0008093	bf	2011-01-27T01:32:51Z		True			molecular_function											owl:Class	
GO:0006143	biolink:NamedThing	obsolete purine metabolic process	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	purine metabolic process					This term was made obsolete because more appropriate terms were created.	GO:0006163|GO:0042278|GO:0006144				True			biological_process											owl:Class	
GO:0039568	biolink:NamedThing	obsolete suppression by virus of host STAT1 activity by inhibition of DNA binding	OBSOLETE. Any process in which a virus stops, prevents, or reduces STAT1-dependent gene transcription, by preventing STAT1 from binding to promoter sites in the nucleus.	tmpzr1t_l9r_go_relaxed.owl	suppression by virus of host STAT1 activity by negative regulation of DNA binding|inhibition of DNA binding of STAT1					The reason for obsoleting this term is that it is too specific. The exact molecular roles of the individual proteins should be captured separately.		bf	2012-03-12T04:31:58Z		True			biological_process											owl:Class	
GO:0038082	biolink:NamedThing	obsolete MAP kinase phosphatase activity involved in regulation of osmosensory signaling pathway	OBSOLETE. Catalysis of the reaction: a phosphorylated MAP kinase + H2O = a MAP kinase + phosphate, where the MAP kinase (MAPK) is part of a MAPK signaling cascade that passes on a signal within an osmosensory signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	MAPK phosphatase activity involved in regulation of osmosensory signaling pathway|MAP kinase phosphatase activity involved in regulation of osmosensory signalling pathway|Hog1 phosphatase activity					This term has been obsoleted because it represents a GO-CAM model rather than a single GO term.		bf	2012-01-26T02:41:31Z		True			molecular_function											owl:Class	
GO:0004196	biolink:NamedThing	obsolete saccharopepsin activity	OBSOLETE. Catalysis of the degradation of gelatin; little activity on hemoglobin. Specificity on B chain of insulin more restricted than pepsin A; does not cleave Phe1-Val2, Gln4-His5 or Gly23-Phe24.	tmpzr1t_l9r_go_relaxed.owl	saccharomyces cerevisiae aspartic proteinase A|yeast proteinase A|saccharopepsin activity|proteinase A|PRA|aspartic proteinase yscA|saccharomyces aspartic proteinase activity|yeast endopeptidase A activity|proteinase yscA|Saccharomyces aspartic proteinase activity			GO:0004190		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0072460	biolink:NamedThing	obsolete detection of stimulus involved in meiotic recombination checkpoint	OBSOLETE. The series of events in which information about whether recombination is complete is received and converted into a molecular signal, contributing to a meiotic recombination checkpoint.	tmpzr1t_l9r_go_relaxed.owl	sensing involved in meiotic recombination checkpoint|meiotic recombination checkpoint sensor process|meiotic recombination checkpoint sensor mechanism	https://github.com/geneontology/go-ontology/issues/20976				This term was obsoleted because it corresponds to a molecular function.		mah	2010-12-09T11:36:42Z		True			biological_process											owl:Class	
GO:0045020	biolink:NamedThing	obsolete error-prone DNA repair	OBSOLETE. DNA repair pathways that tend to increase the endogenous mutation rate.	tmpzr1t_l9r_go_relaxed.owl	mutagenic DNA repair|error-prone DNA repair					This term was made obsolete because 'error-prone' does not correspond to a repair mechanism, and the term has been superseded by more specific terms.	GO:0042276				True			biological_process											owl:Class	
GO:0015448	biolink:NamedThing	obsolete type III protein (virulence-related) secretor activity	OBSOLETE. This term was not defined before being made obsolete.	tmpzr1t_l9r_go_relaxed.owl	type III protein (virulence-related) secretor activity					This term was made obsolete because it does not accurately reflect the function of the proteins involved.					True			molecular_function											owl:Class	
GO:0090203	biolink:NamedThing	obsolete transcriptional activation by promoter-terminator looping	OBSOLETE. The formation and maintenance of DNA loops that juxtapose the promoter and terminator regions of RNA polymerase II-transcribed genes and activate transcription from an RNA polymerase II promoter.	tmpzr1t_l9r_go_relaxed.owl	transcriptional activation by memory gene loops	https://github.com/geneontology/go-ontology/issues/20204				This term was obsoleted because it was defined like a molecular function.	GO:0045893	tb	2009-12-18T11:58:32Z		True			biological_process											owl:Class	
GO:0047764	biolink:NamedThing	obsolete caldesmon kinase activity	OBSOLETE. Catalysis of the reaction: ATP + caldesmon = ADP + caldesmon phosphate.	tmpzr1t_l9r_go_relaxed.owl					MetaCyc:2.7.11.17-RXN	This term was made obsolete because it represents a specific gene product.					True			molecular_function											owl:Class	
GO:0017021	biolink:NamedThing	obsolete myosin phosphatase myosin binding	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	myosin phosphatase myosin binding					This term was made obsolete because it describes the binding of myosin phosphatase to myosin, which is not a molecular function.	GO:0017022|GO:0017018				True			molecular_function											owl:Class	
GO:0015331	biolink:NamedThing	obsolete asparagine/glutamine permease activity	OBSOLETE. Catalysis of the stereospecific transfer of asparagine or glutamine across a biological membrane.	tmpzr1t_l9r_go_relaxed.owl	asparagine/glutamine permease activity					This term was made obsolete because it represents a multifunctional gene product.	GO:0015186|GO:0015182|GO:0022857				True			molecular_function											owl:Class	
GO:0072448	biolink:NamedThing	obsolete detection of stimulus involved in G1 cell size control checkpoint	OBSOLETE. The series of events in which information about cell size is received and converted into a molecular signal, contributing to a mitotic cell cycle G1/S transition size control checkpoint.	tmpzr1t_l9r_go_relaxed.owl	mitotic cell cycle G1/S transition size control checkpoint sensor mechanism|detection of stimulus involved in mitotic cell cycle G1/S transition size control checkpoint|sensing involved in mitotic cell cycle G1/S transition size control checkpoint|mitotic cell cycle G1/S transition size control checkpoint sensor process	https://github.com/geneontology/go-ontology/issues/20976				This term was obsoleted because it corresponds to a molecular function.		mah	2010-12-09T10:56:32Z		True			biological_process											owl:Class	
GO:0005709	biolink:NamedThing	obsolete prophase chromosome	OBSOLETE. A chromosome found in the cell during prophase.	tmpzr1t_l9r_go_relaxed.owl	prophase chromosome					This term was made obsolete because it is based on a temporal division of the cell cycle.	GO:0005694				True			cellular_component											owl:Class	
GO:0015500	biolink:NamedThing	obsolete threonine/serine:sodium symporter activity	OBSOLETE. Catalysis of the reaction: (threonine or serine)(out) + Na+(out) = (threonine or serine)(in) + Na+(in).	tmpzr1t_l9r_go_relaxed.owl	threonine/serine:sodium symporter activity					This term was made obsolete because it represents a multifunctional gene product.	GO:0015194|GO:0005283|GO:0015195				True			molecular_function											owl:Class	
GO:0052440	biolink:NamedThing	obsolete modulation by organism of defense-related symbiont ethylene-mediated signal transduction pathway	OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of symbiont ethylene-mediated signal transduction pathways during the symbiont defense response. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	modulation by organism of defense-related symbiont ethylene-mediated signal transduction pathway					This term was made obsolete because it does not represent a real biological process.					True			biological_process											owl:Class	
GO:0000233	biolink:NamedThing	obsolete cytoplasmic interphase chromosome	OBSOLETE. A chromosome found in the cytoplasm during interphase.	tmpzr1t_l9r_go_relaxed.owl	cytoplasmic interphase chromosome					This term was made obsolete because it is based on a temporal division of the cell cycle.	GO:0005694				True			cellular_component											owl:Class	
GO:0017164	biolink:NamedThing	obsolete nicotinic acetylcholine receptor-associated protein activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	nicotinic acetylcholine receptor-associated protein activity					This term was made obsolete because it represents a gene product and not a molecular function.	GO:0005515|GO:0005102				True			molecular_function											owl:Class	
GO:0045558	biolink:NamedThing	obsolete TRAIL receptor 1 biosynthetic process	OBSOLETE. The chemical reactions and pathways resulting in the formation of TRAIL-R1 (TNF-related apoptosis inducing ligand receptor 1), which engages a caspase-dependent apoptotic pathway.	tmpzr1t_l9r_go_relaxed.owl	TRAIL receptor 1 anabolism|TRAIL receptor 1 biosynthesis|tumor necrosis factor receptor superfamily member 10A biosynthetic process|TRAIL receptor 1 synthesis|TRAIL receptor 1 formation	https://github.com/geneontology/go-ontology/issues/19900				The reason for obsoletion is that those represent specific gene products, and genes annotated to those terms should be annotated to 'regulation of gene expression' or 'regulation of transcription' or some signaling term.					True			biological_process											owl:Class	
GO:0034884	biolink:NamedThing	obsolete gamma-N-formylaminovinylacetaldehyde dehydrogenase activity	OBSOLETE. Catalysis of the reaction: gamma-N-formylaminovinylacetaldehyde + H2O = gamma-N-formylaminovinylacetate + 2 H+ + 2 e-.	tmpzr1t_l9r_go_relaxed.owl	gamma-N-formylaminovinylacetaldehyde dehydrogenase activity					This term was made obsolete because it was derived from a UM-BBD enzyme entry that has been deleted, and no other information can be found to suggest that it is a naturally occurring activity.	GO:0016903				True			molecular_function											owl:Class	
GO:0075174	biolink:NamedThing	obsolete regulation of cAMP-mediated signaling in response to host	OBSOLETE. Any process in which the symbiont organism modulates the frequency, rate or extent of its cAMP-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	regulation of cAMP-mediated signal transduction in response to host|regulation of cAMP-mediated signalling in response to host|regulation of symbiont cAMP-mediated signal transduction in response to host					This term was obsoleted because there is no evidence that this process exists.					True			biological_process											owl:Class	
GO:0030442	biolink:NamedThing	obsolete inactivation of MAPK during sporulation (sensu Fungi)	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	inactivation of MAPK during sporulation (sensu Fungi)					This term was made obsolete because it is a gene product specific term.					True			biological_process											owl:Class	
GO:0072415	biolink:NamedThing	obsolete detection of stimulus involved in spindle checkpoint	OBSOLETE. The series of events in which information about the assembly, orientation or integrity of the spindle is received and converted into a molecular signal, contributing to a spindle checkpoint.	tmpzr1t_l9r_go_relaxed.owl	spindle checkpoint sensor mechanism|spindle checkpoint sensor process|sensing involved in spindle checkpoint	https://github.com/geneontology/go-ontology/issues/20976				This term was obsoleted because it corresponds to a molecular function.		mah	2010-12-08T03:54:50Z		True			biological_process											owl:Class	
GO:0030464	biolink:NamedThing	obsolete aging dependent sterility (sensu Fungi)	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	aging dependent sterility (sensu Fungi)					This term was made obsolete because it reflected a trait or phenotype.	GO:0030466				True			biological_process											owl:Class	
GO:0005553	biolink:NamedThing	obsolete ubiquitin-ribosomal protein fusion protein	OBSOLETE. A protein encoded by some ubiquitin genes which consists of a single copy of ubiquitin fused to a ribosomal protein.	tmpzr1t_l9r_go_relaxed.owl	ubiquitin-ribosomal protein fusion protein					This term was made obsolete because it describes a gene product.					True			molecular_function											owl:Class	
GO:0039607	biolink:NamedThing	obsolete proteolysis by virus of host translation initiation factor	OBSOLETE. The chemical reactions and pathways performed by a virus resulting in the hydrolysis of a host translation initiation factor by cleavage of its peptide bonds.	tmpzr1t_l9r_go_relaxed.owl	proteolytic cleavage by virus of host translation initiation factor|suppression by virus of host translation initiation factor activity by proteolysis|cleavage of host translation initiation factor by viral protease|cleavage of host translation initiation factor by virus					The reason for obsoleting this term is that it is too specific. The exact molecular roles of the individual proteins should be captured separately.		bf	2012-07-05T04:46:21Z		True			biological_process											owl:Class	
GO:0008439	biolink:NamedThing	obsolete monophenol monooxygenase activator activity	OBSOLETE. Increases the activity of the enzyme monophenol monooxygenase.	tmpzr1t_l9r_go_relaxed.owl	prophenol oxidase activator|monophenol monooxygenase activator activity			GO:0004252		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0007238	biolink:NamedThing	obsolete activation of Pbs2	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	activation of Pbs2					This term was made obsolete because it contains gene product and species specific information.					True			biological_process											owl:Class	
GO:0004284	biolink:NamedThing	obsolete acrosin activity	OBSOLETE. Catalysis of the preferential cleavage of Arg-Xaa > Lys-Xaa.	tmpzr1t_l9r_go_relaxed.owl	acrosin activity|acrosin amidase activity|alpha-acrosin|psi-acrosin|acrozonase activity|acrosomal proteinase activity|beta-acrosin|acrosomal protease activity			GO:0004252		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0052399	biolink:NamedThing	obsolete induction by organism of symbiont programmed cell death	OBSOLETE. The activation by an organism of programmed cell death in the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	activation by organism of symbiont programmed cell death|induction by organism of symbiont programmed cell death					This term was made obsolete because it does not represent a real biological process.					True			biological_process											owl:Class	
GO:0075204	biolink:NamedThing	obsolete negative regulation of symbiont penetration hypha formation for entry into host	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of symbiont penetration hypha formation for entry into host. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/18779				This term was obsoleted because there is no evidence that this process exists.					True			biological_process											owl:Class	
GO:0031015	biolink:NamedThing	obsolete karyopherin docking complex	OBSOLETE. A subcomplex of the nuclear pore complex that interacts with karyopherin-cargo complexes; a well-characterized example in Saccharomyces contains Asm4p, Nup53p, and Nup170p.	tmpzr1t_l9r_go_relaxed.owl	karyopherin docking complex|Asm4p-containing complex|nuclear pore subcomplex						GO:0017056|GO:0044613				True			cellular_component											owl:Class	
GO:0052193	biolink:NamedThing	obsolete movement in symbiont environment	OBSOLETE. The directed movement of an organism or motile cell on, within or near its symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl											True			biological_process											owl:Class	
GO:0042142	biolink:NamedThing	obsolete heavy metal chelation	OBSOLETE. The strong but reversible binding of a heavy metal ion by a larger molecule such as protein.	tmpzr1t_l9r_go_relaxed.owl	heavy metal chelation			GO:0046911		This term was made obsolete because it represents a molecular function and not a biological process.					True			biological_process											owl:Class	
GO:0051860	biolink:NamedThing	obsolete evasion or tolerance of symbiont defenses	OBSOLETE. The process, either active or passive, by which an organism evades or tolerates the effects of the defense(s) or defense molecules of a symbiont organism. Symbiont defenses may be induced by the presence of the organism or may be preformed (e.g. physical barriers). The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/14862				This term was made obsolete because it is not relevant for the host in a host-symbiont interaction.					True			biological_process											owl:Class	
GO:0046853	biolink:NamedThing	obsolete inositol or phosphatidylinositol phosphorylation	OBSOLETE. The process of introducing a phosphate group into inositol or a phosphatidylinositol. Inositol is the cyclic alcohol 1,2,3,4,5,6-cyclohexanehexol, which is widely distributed in nature and acts as a growth factor in animals and microorganisms.	tmpzr1t_l9r_go_relaxed.owl	inositol and derivative phosphorylation|inositol or phosphatidylinositol phosphorylation|myo-inositol or phosphatidyl-myo-inositol phosphorylation|myo-inositol and derivative phosphorylation					This term was made obsolete because it is a grouping term representing two quite different sets of entities, hexose sugars and glycerophospholipids.	GO:0046854|GO:0052746				True			biological_process											owl:Class	
GO:0016915	biolink:NamedThing	obsolete activin	OBSOLETE. A nonsteroidal regulator, composed of two covalently linked beta subunits, that is synthesized in the pituitary gland and gonads and stimulates the secretion of follicle-stimulating hormone.	tmpzr1t_l9r_go_relaxed.owl	activin					This term was made obsolete because it represents a gene product.	GO:0046881|GO:0005160				True			molecular_function											owl:Class	
GO:0006920	biolink:NamedThing	obsolete commitment to apoptosis	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	commitment to apoptosis					This term was made obsolete because more accurate terms were created.	GO:0006915				True			biological_process											owl:Class	
GO:0000190	biolink:NamedThing	obsolete MAPKKK cascade (pseudohyphal growth)	OBSOLETE. MAPKKK cascade involved in transduction of signal promoting pseudohyphal or invasive growth.	tmpzr1t_l9r_go_relaxed.owl	MAPKKK cascade (pseudohyphal growth)					This term was made obsolete because it is a gene product specific term.					True			biological_process											owl:Class	
GO:0075013	biolink:NamedThing	obsolete growth or development of symbiont on or near host phyllosphere	OBSOLETE. The increase in size or mass of symbiont, or the progression of the symbiont from an initial condition to a later condition, occurring on or near its host phyllosphere. The host phyllosphere is defined as total above-ground surfaces of a plant as a habitat for symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	growth or development of symbiont on or near host phyllosphere										True			biological_process											owl:Class	
GO:0009869	biolink:NamedThing	obsolete incompatible pollen-pistil interaction	OBSOLETE. An interaction between a pollen grain and pistil that results in inhibition of pollen germination/growth.	tmpzr1t_l9r_go_relaxed.owl	incompatible pollen-pistil interaction					This term was made obsolete because it represents a phenotype.					True			biological_process											owl:Class	
GO:0030053	biolink:NamedThing	obsolete immunophilin	OBSOLETE. Any member of a family of receptors that includes the major FK506 binding protein FKBP and cyclophilin. These two proteins are unrelated in amino-acid sequence, but both possess peptidyl-prolyl isomerase activity which is blocked by immunosuppressants that block signal-transduction pathways leading to T cell activation such as FK506 and rapamycin, which block FKBP, or cyclosporin A, which blocks cyclophilin.	tmpzr1t_l9r_go_relaxed.owl	immunophilin					This term was made obsolete because it does not represent a molecular function.	GO:0003755				True			molecular_function											owl:Class	
RO:0002231	biolink:NamedThing	has start location		tmpzr1t_l9r_go_relaxed.owl					RO:0002231									external									has_start_location			
GO:0035420	biolink:NamedThing	obsolete MAPK cascade involved in innate immune response	OBSOLETE. A MAPK cascade that contributes to an innate immune response, a defense response mediated by germline encoded components that directly recognize components of potential pathogens.	tmpzr1t_l9r_go_relaxed.owl	MAPKKK cascade involved in innate immune response	https://github.com/geneontology/go-ontology/issues/14323				This term was obsoleted because it represents a GO-CAM model.		bf	2010-03-29T01:25:59Z		True			biological_process											owl:Class	
GO:0009766	biolink:NamedThing	obsolete primary charge separation	OBSOLETE. In the photosynthetic reaction centers, primary charge separation is initiated by the excitation of a molecule followed by the transfer of an electron to an electron acceptor molecule following energy transfer from light harvesting complexes.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it represents a mechanism, and is outside the scope of GO.					True			biological_process											owl:Class	
GO:0090115	biolink:NamedThing	obsolete C-5 methylation on cytosine involved in chromatin silencing	OBSOLETE. The covalent transfer of a methyl group to C-5 of cytosine in a DNA molecule that contributes to chromatin silencing.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it represents a molecular function.		tb	2009-12-07T11:55:16Z		True			biological_process											owl:Class	
RO:0003000	biolink:NamedThing	produces		tmpzr1t_l9r_go_relaxed.owl					RO:0003000									external									produces			
GO:0035415	biolink:NamedThing	obsolete regulation of mitotic prometaphase	OBSOLETE. Any process that modulates the frequency, rate or extent of mitotic prometaphase, the stage following prophase in mitosis (in higher eukaryotes) during which the nuclear envelope is disrupted and breaks into membrane vesicles, and the spindle microtubules enter the nuclear region.	tmpzr1t_l9r_go_relaxed.owl	regulation of mitotic prometaphase					This term was made obsolete as part of the cell cycle overhaul. This is because it was decided that cell cycle phases are intervals and so cannot be regulated, rather it is the transitions between the phases that are regulated.		bf	2010-03-29T10:52:08Z		True			biological_process											owl:Class	
GOREL:0001019	biolink:NamedThing	results_in_division_of		tmpzr1t_l9r_go_relaxed.owl					GOREL:0001019	use occurs_in								external									results_in_division_of			
GO:0044412	biolink:NamedThing	obsolete growth or development of symbiont in host	OBSOLETE. The increase in size or mass of an organism, or the progression of an organism from an initial condition to a later condition, occurring within the cells or tissues of the host organism. This may (but not necessarily) include a filamentous growth form, and also can include secretion of proteases and lipases to break down host tissue. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	growth or development of symbiont within host|growth or development of symbiont in host|growth or development of organism within host|invasive growth					This term was made obsolete because it contained a conjunction (or).	GO:0051701|GO:0044114				True			biological_process											owl:Class	
GO:0007235	biolink:NamedThing	obsolete activation of Ypd1 protein	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	activation of Ypd1 protein					This term was made obsolete because it contains gene product and species specific information.					True			biological_process											owl:Class	
GO:1903245	biolink:NamedThing	obsolete regulation of adrenergic receptor signaling pathway involved in positive regulation of heart rate	OBSOLETE. Any process that modulates the frequency, rate or extent of adrenergic receptor signaling pathway involved in positive regulation of heart rate.	tmpzr1t_l9r_go_relaxed.owl	regulation of beta adrenergic receptor signaling pathway involved in positive regulation of heart rate|regulation of If activation by beta-adrenergic receptor signaling pathway|regulation of adrenergic receptor signalling pathway involved in positive regulation of heart rate|regulation of activation of funny current by beta-adrenergic receptor signaling pathway|regulation of adenylate cyclase-activating cardiac adrenergic receptor signaling pathway|regulation of Gs-coupled adrenergic receptor signaling pathway involved in positive regulation of heart rate	https://github.com/geneontology/go-ontology/issues/14733				This term was obsoleted because it is not precise enough. We must specify if the ACA-activating or ACA inhibiting pathway is the target of the regulation.		rl	2014-08-04T11:53:54Z		True			biological_process											owl:Class	
GO:0075098	biolink:NamedThing	obsolete negative regulation by host of symbiont signal transduction mediated by G-protein gamma subunit	OBSOLETE. Any process in which the host organism stops, prevents, or reduces the frequency, rate or extent of the symbiont signal transduction mediated by G-protein gamma subunit. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl						The reason for obsoletion is that there is no evidence that the host can modulate or regulate a symbiont's signal transduction pathway.					True			biological_process											owl:Class	
GO:0051842	biolink:NamedThing	obsolete evasion or tolerance of symbiont immune response	OBSOLETE. Any process, either active or passive, by which an organism avoids the effects of the symbiont organism's immune response. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	immune evasion|evasion or tolerance of symbiont immune response					This term was made obsolete because it does not represent a valid biological process that occurs in nature.					True			biological_process											owl:Class	
GO:0016146	biolink:NamedThing	obsolete protein-synthesizing GTPase activity, initiation	OBSOLETE. Catalysis of the reaction: GTP + H2O = GDP + phosphate.	tmpzr1t_l9r_go_relaxed.owl	protein-synthesizing GTPase activity, initiation					This term was made obsolete because it contains both process and function information.	GO:0003924|GO:0006413|GO:0006412|GO:0003743				True			molecular_function											owl:Class	
GO:0010149	biolink:NamedThing	obsolete senescence	OBSOLETE. A preprogrammed process associated with the dismantling of an anatomical structure and an overall decline in metabolism. This may include the breakdown of organelles, membranes and other cellular components. An example of this process is found in Arabidopsis thaliana, when older leaves or floral organs are shed.	tmpzr1t_l9r_go_relaxed.owl	senescence				Wikipedia:Senescence	This term was made obsolete because its name is ambiguous and it is covered by the two more specific terms: 'organ senescence ; GO:0010260' and 'cell aging ; GO:0007569'.					True			biological_process											owl:Class	
GO:0001529	biolink:NamedThing	obsolete elastin	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	elastin			GO:0030023		This term was made obsolete because it represents a gene product.					True			cellular_component											owl:Class	
GO:0005617	biolink:NamedThing	obsolete larval serum protein-1	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	larval serum protein-1|LSP1					This term was made obsolete because it represents a gene product.					True			cellular_component											owl:Class	
GO:0052057	biolink:NamedThing	obsolete modification by symbiont of host morphology or physiology via protein secreted by type III secretion system	OBSOLETE. The process in which an organism effects a change in the structure or function of its host organism, mediated by a substance secreted by a type III secretion system in the organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it conflated the process in which a gene product is involved with the secretion system by which it reaches its target.					True			biological_process											owl:Class	
GO:0052350	biolink:NamedThing	obsolete induction by organism of induced systemic resistance in symbiont	OBSOLETE. Any process in which an organism activates induced systemic resistance in the symbiont; induced systemic resistance is a response that confers broad spectrum systemic resistance to disease and that does not depend upon salicylic acid signaling. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	activation by organism of ISR in symbiont|induction by organism of ISR in symbiont|induction by organism of induced systemic resistance in symbiont|activation by organism of induced systemic resistance in symbiont					This term was made obsolete because it does not represent a real biological process.					True			biological_process											owl:Class	
GO:0051198	biolink:NamedThing	obsolete negative regulation of coenzyme metabolic process	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving a coenzyme.	tmpzr1t_l9r_go_relaxed.owl	down regulation of coenzyme metabolic process|negative regulation of coenzyme metabolism|negative regulation of coenzyme and prosthetic group metabolism|down-regulation of coenzyme metabolic process|negative regulation of coenzyme and prosthetic group metabolic process|inhibition of coenzyme metabolic process|downregulation of coenzyme metabolic process					1. Making inferences in GO about compounds based on the coenzyme role curated by ChEBI creates relationships that are not always true which violates ontological principles for GO; therefore we will cease making these inferences. 2. It is not meaningful to group metabolic processes that are not all metabolically related by the fact that they may be used as a coenzyme.					True			biological_process											owl:Class	
GO:0016285	biolink:NamedThing	obsolete cytosol alanyl aminopeptidase activity	OBSOLETE. Catalysis of the release of an N-terminal amino acid, preferentially alanine, from a wide range of peptides, amides and arylamides.	tmpzr1t_l9r_go_relaxed.owl	puromycin-sensitive aminopeptidase activity|human liver aminopeptidase|arylamidase activity|cytosol aminopeptidase III activity|soluble alanyl aminopeptidase activity|aminopolypeptidase activity|liver aminopeptidase activity|thiol-activated aminopeptidase activity|cytosol alanyl aminopeptidase activity				EC:3.4.11.14|MetaCyc:3.4.11.14-RXN	This term was made obsolete because it represents a gene product and refers to cellular component information.	GO:0004177|GO:0008235				True			molecular_function											owl:Class	
GO:1903470	biolink:NamedThing	obsolete actomyosin contractile ring assembly involved in mitotic cell cycle	OBSOLETE. Any actomyosin contractile ring assembly that is involved in mitotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl	constriction ring assembly involved in mitotic cell cycle|cytokinesis, contractile ring assembly involved in mitotic cell cycle|cytokinesis, actomyosin contractile ring formation involved in mitotic cell cycle|cytokinesis, actomyosin ring formation involved in mitotic cell cycle|cytokinesis, actomyosin contractile ring assembly involved in mitotic cell cycle|contractile ring assembly involved in mitotic cell cycle|cytokinesis, actomyosin ring biosynthesis involved in mitotic cell cycle					This term was obsoleted at the TermGenie Gatekeeper stage.		vw	2014-09-23T14:06:50Z		True			biological_process											owl:Class	
GO:0030531	biolink:NamedThing	obsolete small cytoplasmic ribonucleoprotein complex	OBSOLETE. A complex composed of RNA of the small cytoplasmic RNA (scRNA) class and protein, found in the cytoplasm.	tmpzr1t_l9r_go_relaxed.owl	scRNP|small cytoplasmic ribonucleoprotein|small cytoplasmic ribonucleoprotein complex			GO:1990904		This term was made obsolete because it was not clearly defined.					True			cellular_component											owl:Class	
GO:0003759	biolink:NamedThing	obsolete glycoprotein-specific chaperone activity	OBSOLETE. Assists in the correct, non-covalent assembly of glycoproteins in vivo, but is not a component of the assembled structures when performing its normal biological function. Utilizes a lectin site as a means to associate with the unfolded glycoproteins.	tmpzr1t_l9r_go_relaxed.owl	glycoprotein-specific chaperone activity					This term was made obsolete because it represents a class of gene products and a biological process rather than a molecular function.	GO:0006457|GO:0051082|GO:0044183				True			molecular_function											owl:Class	
GO:0003719	biolink:NamedThing	obsolete transcription factor binding, cytoplasmic sequestering	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	transcription factor binding, cytoplasmic sequestering			GO:0042994		This term was made obsolete because sequestering is a process rather than a function.					True			molecular_function											owl:Class	
GO:0007572	biolink:NamedThing	obsolete age dependent decreased translational activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	age dependent decreased translational activity					This term was made obsolete because it does not describe a biological process.	GO:0007571				True			biological_process											owl:Class	
GO:0004882	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1902666	biolink:NamedThing	obsolete protein localization to Mmi1 nuclear focus complex	OBSOLETE. A process in which a protein is transported to, or maintained in, a location within a Mmi1 nuclear focus complex.	tmpzr1t_l9r_go_relaxed.owl	protein localisation in Mmi1 nuclear focus complex|protein localization in Mmi1 nuclear focus complex|protein localisation to Mmi1 nuclear focus complex	https://github.com/geneontology/go-ontology/issues/19063				This term was obsoleted because there is no evidence that this process exists (no factor mediates the localization of proteins to Mmi1 nuclear foci)		mah	2014-01-30T10:42:17Z		True			biological_process											owl:Class	
GO:0052051	biolink:NamedThing	obsolete interaction with host via protein secreted by type II secretion system	OBSOLETE. An interaction with the host organism mediated by a substance secreted by the other organism by a type II secretion system. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it conflated the process in which a gene product is involved with the secretion system by which it reaches its target.					True			biological_process											owl:Class	
GO:0003706	biolink:NamedThing	obsolete ligand-regulated transcription factor activity	OBSOLETE. Functions to enable the transcription of specific, or specific sets, of genes by RNA polymerase II in response to a ligand.	tmpzr1t_l9r_go_relaxed.owl	ligand-regulated transcription factor activity					This term was made obsolete because it does not convey any information about the molecular nature of the function or whether the function is based on binding DNA, on interacting with other proteins, or some other mechanism.	GO:0030374|GO:0004879				True			molecular_function											owl:Class	
GO:0007574	biolink:NamedThing	obsolete cell aging (sensu Saccharomyces)	OBSOLETE. Process associated with continued cell division (budding) by the mother cell. Age is often measured by counting the number of bud scars on the cell.	tmpzr1t_l9r_go_relaxed.owl	cell aging (sensu Saccharomyces)			GO:0007569		This term was made obsolete because it does not describe a biological process that is distinct from 'cell aging'.					True			biological_process											owl:Class	
GO:1903453	biolink:NamedThing	obsolete RNA interference involved in olfactory learning	OBSOLETE. Any RNA interference that is involved in olfactory learning.	tmpzr1t_l9r_go_relaxed.owl	RNAi involved in olfactory learning|posttranscriptional gene silencing by siRNA involved in olfactory learning	https://github.com/geneontology/go-ontology/issues/18200				This term was obsoleted because it does not represent a specific pathway.		kmv	2014-09-22T13:50:09Z		True			biological_process											owl:Class	
GO:0042156	biolink:NamedThing	obsolete zinc-mediated transcriptional activator activity	OBSOLETE. Initiates or upregulates transcription in the presence of zinc.	tmpzr1t_l9r_go_relaxed.owl	zinc-mediated transcriptional activator activity					This term was obsoleted because it is defined as a Process term, i.e. it is defined only in terms of the process it acts in and it does NOT convey any information about the molecular nature of the function or whether the function is based on binding DNA, on interacting with other proteins, or some other mechanism. To transfer all annotations without review, the BP term indicated is considered to be equivalent and thus the only appropriate destination for all annotations. To reannotate to a MF term, you will probably need to revisit the original literature or other primary data because this "MF" term was not defined in terms of mechanism of action and there are multiple possibilities in the revised MF structure. In reannotation, please also consider descendent terms of the suggested MF terms as a more specific term may be more appropriate than the MF terms indicated. Please be aware that you may wish to request a new term if the mechanism of action of this gene product is not yet represented or if you are annotating for an RNAP different than one for which there is a specific suggested term. Also note that if there is no information about how the gene product acts, it may be appropriate to annotate to the root term for molecular_function.					True			molecular_function											owl:Class	
GO:0100041	biolink:NamedThing	obsolete positive regulation of pseudohyphal growth by transcription from RNA polymerase II promoter	OBSOLETE. Any transcription from RNA polymerase II promoter process that positively regulates pseudohyphal growth.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it represents a GO-CAM model.		cjm	2015-04-02T04:13:19Z		True			biological_process											owl:Class	
GO:0052404	biolink:NamedThing	obsolete negative regulation by host of symbiont peptidase activity	OBSOLETE. Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of symbiont protease activity, the catalysis of the hydrolysis of peptide bonds in a protein. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	inhibition by host of symbiont protease activity|inhibition of symbiont protease activity|down regulation by host of symbiont protease activity|down-regulation by host of symbiont protease activity|negative regulation by host of symbiont protease activity|downregulation by host of symbiont protease activity	https://github.com/geneontology/go-ontology/issues/21740				This term was obsoleted because it represents a molecular function.					True			biological_process											owl:Class	
GO:0102072	biolink:NamedThing	obsolete 3-oxo-cis-Delta9-hexadecenoyl-[acp] reductase activity	OBSOLETE. Catalysis of the reaction: NADP + a 3R-hydroxy cis Delta9-hexadecenoyl-[acp] <=> NADPH + H+ + a 3-oxo-cis-Delta9-hexadecenoyl-[acp].	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/21876				This term was obsoleted because it represents a specific substrate, and is beyond the specificity of GO.	GO:0004316				True			molecular_function											owl:Class	
GO:0044113	biolink:NamedThing	obsolete development in other organism involved in symbiotic interaction	OBSOLETE. The progression of an organism from an initial condition to a later condition, occurring within the cells or tissues of a second organism, where the two organisms are in a symbiotic interaction. This may (but not necessarily) include a filamentous growth form, and also can include secretion of proteases and lipases to break down the tissue of the second organism.	tmpzr1t_l9r_go_relaxed.owl	development in other organism during symbiotic interaction	https://github.com/geneontology/go-ontology/issues/20305				This term was obsoleted because it represents both a process and a location.		jl	2009-07-30T02:32:38Z		True			biological_process											owl:Class	
GO:0019025	biolink:NamedThing	obsolete positive sense viral genome	OBSOLETE. A single stranded RNA genome with the same nucleotide polarity as mRNA.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it does not represent a GO cellular component.					True			cellular_component											owl:Class	
GO:0006945	biolink:NamedThing	obsolete nuclear fusion during karyogamy	OBSOLETE. The fusion of two haploid nuclei to form a single diploid nucleus, as seen in the yeast mating process.	tmpzr1t_l9r_go_relaxed.owl	nuclear fusion during karyogamy					This term was made obsolete because it is redundant outside the context of Saccharomyces biology.	GO:0000741				True			biological_process											owl:Class	
GO:1905106	biolink:NamedThing	obsolete response to Dizocilpine	OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a Dizocilpine stimulus.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted at the TermGenie Gatekeeper stage.		sl	2016-04-04T20:26:52Z		True			biological_process											owl:Class	
GO:0075156	biolink:NamedThing	obsolete regulation of G protein-coupled receptor signaling pathway in response to host	OBSOLETE. Any process in which the symbiont organism modulates the frequency, rate or extent of its G protein-coupled receptor-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	regulation of G-protein coupled receptor protein signaling pathway in response to host|regulation of symbiont G-protein coupled receptor protein-mediated signal transduction in response to host|regulation of G-protein coupled receptor protein signalling pathway in response to host					This term was obsoleted because there is no evidence that this process exists.					True			biological_process											owl:Class	
GO:0035300	biolink:NamedThing	obsolete inositol-1,3,4-trisphosphate 5/6-kinase activity	OBSOLETE. Catalysis of the reactions: ATP + 1D-myo-inositol 1,3,4-trisphosphate = ADP + 1D-myo-inositol 1,3,4,5-tetrakisphosphate, and ATP + 1D-myo-inositol 1,3,4-trisphosphate = ADP + 1D-myo-inositol 1,3,4,6-tetrakisphosphate.	tmpzr1t_l9r_go_relaxed.owl	inositol 1,3,4-trisphosphate 6-kinase activity|inositol-1,3,4-trisphosphate 5/6-kinase activity|inositol trisphosphate 5/6-kinase activity|Ins(1,3,4)P3 5/6-kinase activity|IP56K|ATP:1D-myo-inositol 1,3,4-trisphosphate 5-phosphotransferase activity|inositol 1,3,4-trisphosphate 5-kinase activity					This term was made obsolete because it represents two reactions, and should be two separate terms.	GO:0052725|GO:0052726				True			molecular_function											owl:Class	
GO:0006460	biolink:NamedThing	obsolete peptidyl-prolyl isomerase B reaction	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	peptidyl-prolyl isomerase B reaction					This term was made obsolete because it represents a molecular function and not a biological process.	GO:0003755				True			biological_process											owl:Class	
GO:0055066	biolink:NamedThing	obsolete di-, tri-valent inorganic cation homeostasis	OBSOLETE. Any process involved in the maintenance of an internal steady state of divalent or trivalent cations within an organism or cell.	tmpzr1t_l9r_go_relaxed.owl	di-, tri-valent inorganic cation homeostasis					This term was made obsolete because it has been split.	GO:0072507|GO:0072508				True			biological_process											owl:Class	
GO:0045866	biolink:NamedThing	obsolete positive regulation of recombination within rDNA repeats	OBSOLETE. Any process that activates or increases the frequency, rate or extent of genetic recombination within the DNA of the genes coding for ribosomal RNA.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of recombination within rDNA repeats					This term was made obsolete because it describes a substrate-specific process.	GO:0045951				True			biological_process											owl:Class	
GO:0045045	biolink:NamedThing	obsolete secretory pathway	OBSOLETE. The pathway along which proteins and other substances are moved around and out of the cell. After synthesis on the ribosomes of the endoplasmic reticulum (ER), completed polypeptide chains are moved to the Golgi complex and subsequently sorted to various destinations. Proteins synthesized and sorted in the secretory pathway include not only those that are secreted from the cell but also enzymes and other resident proteins in the lumen of the ER, Golgi, and lysosomes as well as integral proteins in the membranes of these organelles and the plasma membrane.	tmpzr1t_l9r_go_relaxed.owl	secretory pathway			GO:0032940		This term was made obsolete because it artificially groups a number of other terms, leading to path problems, its definition is unclear (and lacks genus-differentia features), and it has probably been used incorrectly in annotations.					True			biological_process											owl:Class	
GO:0052144	biolink:NamedThing	obsolete negative energy taxis in host	OBSOLETE. The directed movement of a motile cell or organism within its host organism towards a lower level of a physical stimulus involved in energy generation, such as light, oxygen, and oxidizable substrates. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	negative energy taxis within host	https://github.com/geneontology/go-ontology/issues/18819				This term was obsoleted because it represents both a process and a location.					True			biological_process											owl:Class	
GO:0042576	biolink:NamedThing	obsolete aspartyl aminopeptidase activity	OBSOLETE. Catalysis of the release of an N-terminal aspartate or glutamate from a peptide, with a preference for aspartate.	tmpzr1t_l9r_go_relaxed.owl	aspartyl aminopeptidase activity			GO:0004177		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0030804	biolink:NamedThing	obsolete positive regulation of cyclic nucleotide biosynthetic process	OBSOLETE. Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cyclic nucleotides.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of cyclic nucleotide anabolism|up regulation of cyclic nucleotide biosynthetic process|upregulation of cyclic nucleotide biosynthetic process|positive regulation of cyclic nucleotide biosynthesis|positive regulation of cyclic nucleotide formation|stimulation of cyclic nucleotide biosynthetic process|positive regulation of cyclic nucleotide synthesis|up-regulation of cyclic nucleotide biosynthetic process|activation of cyclic nucleotide biosynthetic process					The reason for obsoletion is that this term represents the regulation of a signaling pathway, not regulation of metabolism.					True			biological_process											owl:Class	
GO:0072467	biolink:NamedThing	obsolete response to cell shape checkpoint signaling	OBSOLETE. A process that occurs in response to signals generated as a result of cell shape checkpoint signaling.	tmpzr1t_l9r_go_relaxed.owl	cell shape checkpoint effector process|response to signal involved in cell shape checkpoint					This term was made obsolete because it was ambiguous.		mah	2010-12-09T11:44:11Z		True			biological_process											owl:Class	
GO:0022825	biolink:NamedThing	obsolete copper-exporting ATPase activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	copper-exporting ATPase activity			GO:0043682		This term was made obsolete because it was a placeholder during work on transporter terms, and was not defined.					True			molecular_function											owl:Class	
GO:0052007	biolink:NamedThing	obsolete biosynthesis by symbiont of substance in host	OBSOLETE. The chemical reactions and pathways performed by an organism in its host resulting in the formation of substances. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	biosynthesis by organism of substance in host	https://github.com/geneontology/go-ontology/issues/18787				This term was obsoleted because there is no evidence that this process exists.					True			biological_process											owl:Class	
GO:0005373	biolink:NamedThing	obsolete heavy metal ion porter activity	OBSOLETE. A transporter of heavy metal ions that utilizes a carrier-mediated process to catalyze uniport, symport or antiport between aqueous phases on either side of a lipid membrane.	tmpzr1t_l9r_go_relaxed.owl	heavy metal ion porter activity|metal ion transporter					This term was made obsolete because it represents a gene product and not a molecular function.	GO:0015291|GO:0046873				True			molecular_function											owl:Class	
GO:0015597	biolink:NamedThing	obsolete histidine/arginine/lysine/ornithine porter activity	OBSOLETE. Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + polar amino acid(out) = ADP + phosphate + polar amino acid(in).	tmpzr1t_l9r_go_relaxed.owl	histidine/arginine/lysine/ornithine porter activity					This term was made obsolete because it represents a multifunctional gene product.	GO:0000064|GO:0005290|GO:0061459|GO:0015426|GO:0015189				True			molecular_function											owl:Class	
GO:0004205	biolink:NamedThing	obsolete caspase-8 activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	caspase-8 activity			GO:0004197		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0052571	biolink:NamedThing	obsolete response to symbiont immune response	OBSOLETE. A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detecting the immune response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	response to symbiont immune response					This term was made obsolete because it does not represent a real biological process.					True			biological_process											owl:Class	
GO:0070055	biolink:NamedThing	obsolete mRNA endonucleolytic cleavage involved in unfolded protein response	OBSOLETE. The endonucleolytic cleavage of a mRNA containing an HAC1-type intron at the 5' and 3' splice sites. The cleavage step is part of unconventional mRNA splicing, and contributes to the endoplasmic reticulum unfolded protein response.	tmpzr1t_l9r_go_relaxed.owl	HAC1-type intron splice site recognition and cleavage|ERN1-mediated XBP-1 mRNA cleavage|XBP1 mRNA cleavage|HAC1 mRNA cleavage|IRE1-mediated XBP-1 mRNA cleavage					The reason for obsoletion is that this process represents a single step (molecular function)  of the IRE1-mediated unfolded protein response (GO:0036498).	GO:0036498				True			biological_process											owl:Class	
GO:1990241	biolink:NamedThing	obsolete nucleotide binding complex	OBSOLETE. A protein complex that interacts selectively and non-covalently with a nucleotide, any compound consisting of a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose or deoxyribose. An example of this is STING in E. coli (Q86WV6).	tmpzr1t_l9r_go_relaxed.owl	nucleotide binding complex					This term was obsoleted at the TermGenie Gatekeeper stage.		bhm	2013-11-22T16:22:07Z		True			cellular_component											owl:Class	
GO:0017026	biolink:NamedThing	obsolete procollagen C-endopeptidase activity	OBSOLETE. Catalysis of the cleavage of the C-terminal propeptide at Ala-Asp in type I and II procollagens and at Arg-Asp in type III.	tmpzr1t_l9r_go_relaxed.owl	procollagen carboxy-terminal proteinase activity|procollagen peptidase activity|procollagen C-terminal proteinase activity|procollagen C-proteinase activity|procollagen C-terminal peptidase activity|carboxyprocollagen peptidase activity|procollagen carboxypeptidase activity|BMP1|procollagen C-endopeptidase activity			GO:0004222		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0046242	biolink:NamedThing	obsolete o-xylene biosynthetic process	OBSOLETE. The chemical reactions and pathways resulting in the formation of o-xylene, (1,2-dimethylbenzene) a colorless, liquid aromatic hydrocarbon.	tmpzr1t_l9r_go_relaxed.owl	o-xylene anabolism|o-xylene biosynthetic process|ortho-xylene biosynthesis|o-xylene synthesis|ortho-xylene biosynthetic process|o-xylene formation|o-xylene biosynthesis			GO:0018950		This term was made obsolete because o-xylene is not synthesized by living organisms, and GO does not cover non-biological processes.					True			biological_process											owl:Class	
GO:0052118	biolink:NamedThing	obsolete positive energy taxis in host environment	OBSOLETE. The directed movement of a motile cell or organism on, within or near its host organism towards a higher level of a physical stimulus involved in energy generation, such as light, oxygen, and oxidizable substrates. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	positive energy taxis in response to host environment	https://github.com/geneontology/go-ontology/issues/18819				This term was obsoleted because it represents both a process and a location.					True			biological_process											owl:Class	
GO:0051847	biolink:NamedThing	obsolete active evasion of symbiont immune response via regulation of symbiont complement system	OBSOLETE. Any mechanism of active immune avoidance which works by regulating the symbiont complement system, e.g. by possessing complement receptors which mediate attachment to, then infection of, symbiont macrophages, which are eventually destroyed. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	active immune evasion via regulation of symbiont complement system|active evasion of symbiont immune response via regulation of symbiont complement system|active immune evasion via modulation of symbiont complement system					This term was made obsolete because it does not represent a real process that exists in nature.					True			biological_process											owl:Class	
has_output	biolink:NamedThing	has output		tmpzr1t_l9r_go_relaxed.owl					RO:0002234									external									has_output			
GO:0071538	biolink:NamedThing	obsolete SH2 domain-mediated complex assembly	OBSOLETE. A process of protein complex assembly in which the arrangement and bonding together of the set of components that form the protein complex is mediated by an SH2 domain interaction.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it represented a molecular function (binding), not a biological process.  The term represented a domain involved in protein-protein interactions, but no necessarily the process of assembling a complex.		mah	2010-01-08T03:46:16Z		True			biological_process											owl:Class	
GO:0000733	biolink:NamedThing	obsolete DNA strand renaturation	OBSOLETE. The identification and annealing of complementary base pairs in single-strand DNA.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/14671				This term was obsoleted because it represents a molecular function.	GO:0036310				True			biological_process											owl:Class	
GO:0009023	biolink:NamedThing	obsolete tRNA sulfurtransferase	OBSOLETE. Catalysis of the reaction: L-cysteine + activated-tRNA = L-serine + tRNA containing a thionucleotide.	tmpzr1t_l9r_go_relaxed.owl	tRNA sulfurtransferase|tRNA sulphurtransferase activity			GO:0034227			GO:0016783				True			molecular_function											owl:Class	
RO:0002343	biolink:NamedThing	results in growth of		tmpzr1t_l9r_go_relaxed.owl					RO:0002343									external									results_in_growth_of			
GO:0010141	biolink:NamedThing	obsolete guanine, xanthine and their nucleoside salvage	OBSOLETE. The pathway by which guanine, xanthine and their nucleoside from purine nucleotides breakdown are converted back to purine nucleotides. The pathway is important in cells where there is no de-novo purine nucleotides biosynthesis.	tmpzr1t_l9r_go_relaxed.owl	guanine, xanthine and their nucleoside salvage					This term was made obsolete because it represents multiple processes that are represented elsewhere in the process ontology.	GO:0043103|GO:0006178|GO:0006190|GO:0006179				True			biological_process											owl:Class	
GO:1902879	biolink:NamedThing	obsolete negative regulation of BMP signaling pathway involved in spinal cord association neuron specification	OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of BMP signaling pathway involved in spinal cord association neuron specification.	tmpzr1t_l9r_go_relaxed.owl	downregulation of bone morphogenetic protein signaling pathway involved in spinal cord association neuron specification|downregulation of BMP signalling pathway involved in spinal cord association neuron specification|down-regulation of bone morphogenetic protein signalling pathway involved in spinal cord association neuron specification|inhibition of bone morphogenetic protein signaling pathway involved in spinal cord association neuron specification|down regulation of BMP signalling pathway involved in spinal cord association neuron specification|inhibition of bone morphogenetic protein signalling pathway involved in spinal cord association neuron specification|down regulation of bone morphogenetic protein signaling pathway involved in spinal cord association neuron specification|inhibition of BMP signaling pathway involved in spinal cord association neuron specification|negative regulation of bone morphogenetic protein signalling pathway involved in spinal cord association neuron specification|inhibition of BMP signalling pathway involved in spinal cord association neuron specification|down-regulation of BMP signaling pathway involved in spinal cord association neuron specification|downregulation of bone morphogenetic protein signalling pathway involved in spinal cord association neuron specification|negative regulation of BMP signalling pathway involved in spinal cord association neuron specification|negative regulation of bone morphogenetic protein signaling pathway involved in spinal cord association neuron specification|down regulation of BMP signaling pathway involved in spinal cord association neuron specification|down regulation of bone morphogenetic protein signalling pathway involved in spinal cord association neuron specification|down-regulation of BMP signalling pathway involved in spinal cord association neuron specification|downregulation of BMP signaling pathway involved in spinal cord association neuron specification|down-regulation of bone morphogenetic protein signaling pathway involved in spinal cord association neuron specification					The reason for obsoletion is that this term represents a GO-CAM model.		mr	2014-04-03T15:25:38Z		True			biological_process											owl:Class	
GO:0008487	biolink:NamedThing	obsolete prenyl-dependent CAAX protease activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	prenyl-dependent CAAX protease activity			GO:0004222		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0046142	biolink:NamedThing	obsolete negative regulation of coenzyme and prosthetic group metabolic process	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving coenzymes and prosthetic groups.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of coenzyme and prosthetic group metabolic process					This term was made obsolete because it was replaced by more specific terms.	GO:0051201				True			biological_process											owl:Class	
GO:1904085	biolink:NamedThing	obsolete positive regulation of epiboly	OBSOLETE. Any process that activates or increases the frequency, rate or extent of epiboly.	tmpzr1t_l9r_go_relaxed.owl	activation of epiboly|upregulation of epiboly|positive regulation of epiboly|up regulation of epiboly|up-regulation of epiboly					This term was obsoleted at the TermGenie Gatekeeper stage.		dos	2015-03-25T10:53:47Z		True			biological_process											owl:Class	
GO:0030363	biolink:NamedThing	obsolete pre-mRNA cleavage factor activity	OBSOLETE. Any activity required for the process of mRNA cleavage.	tmpzr1t_l9r_go_relaxed.owl	pre-mRNA cleavage factor activity					This term was made obsolete because it describes a biological process.	GO:0006379				True			molecular_function											owl:Class	
GO:1901718	biolink:NamedThing	obsolete regulation of dipeptide transmembrane transport by regulation of transcription from RNA polymerase II promoter	OBSOLETE. A regulation of transcription from RNA polymerase II promoter that results in regulation of dipeptide transmembrane transport.	tmpzr1t_l9r_go_relaxed.owl						The term was obsoleted because it is better represented by a GO-CAM model.		pr	2012-12-19T17:04:04Z		True			biological_process											owl:Class	
GO:1903694	biolink:NamedThing	obsolete positive regulation of mitotic G1 cell cycle arrest in response to nitrogen starvation	OBSOLETE. Any process that activates or increases the frequency, rate or extent of mitotic G1 cell cycle arrest in response to nitrogen starvation.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of G1 mitotic cell cycle arrest in response to nitrogen starvation|up-regulation of G1 mitotic cell cycle arrest in response to nitrogen starvation|upregulation of mitotic G1 cell cycle arrest in response to nitrogen starvation|upregulation of G1 mitotic cell cycle arrest in response to nitrogen starvation|activation of G1 mitotic cell cycle arrest in response to nitrogen starvation|up-regulation of mitotic G1 cell cycle arrest in response to nitrogen starvation|up regulation of G1 mitotic cell cycle arrest in response to nitrogen starvation|up regulation of mitotic G1 cell cycle arrest in response to nitrogen starvation|activation of mitotic G1 cell cycle arrest in response to nitrogen starvation	https://github.com/geneontology/go-ontology/issues/20989				This term was obsoleted because it does not represent a specific process.		al	2014-12-02T18:16:16Z		True			biological_process											owl:Class	
GO:0048610	biolink:NamedThing	obsolete cellular process involved in reproduction	OBSOLETE. A process, occurring at the cellular level, that is involved in the reproductive function of a multicellular or single-celled organism.	tmpzr1t_l9r_go_relaxed.owl	reproductive cellular process|cellular process involved in reproduction					This process was made obsolete because we felt it not provide a particularly useful classification, and its very broad logical definition caused regular problems in our inference pipelines.					True			biological_process											owl:Class	
GO:0044402	biolink:NamedThing	obsolete competition with other organism	OBSOLETE. Any process in which an organism within a multispecies community gains an advantage in growth or survival over another organism of a different species in that community.	tmpzr1t_l9r_go_relaxed.owl	competition with another organism|interspecies competition	https://github.com/geneontology/go-ontology/issues/18568				This term was obsoleted because it is outside the scope of GO.					True			biological_process											owl:Class	
GO:0100029	biolink:NamedThing	obsolete regulation of histone modification by transcription from RNA polymerase II promoter	OBSOLETE. Any transcription from RNA polymerase II promoter process that regulates histone modification.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it describes a process that does not exist.		cjm	2015-04-02T04:13:19Z		True			biological_process											owl:Class	
GO:0052467	biolink:NamedThing	obsolete modulation by organism of symbiont salicylic acid-mediated defense response	OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of the salicylic acid-mediated defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	modulation by organism of symbiont salicylic acid-mediated defense response|modulation by organism of symbiont SA-mediated defense response					This term was made obsolete because it does not represent a real biological process.					True			biological_process											owl:Class	
GO:0030463	biolink:NamedThing	obsolete cell aging (sensu Fungi)	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	cell aging (sensu Fungi)			GO:0007569		This term was made obsolete because it does not describe a biological process that is distinct from 'cell aging'.					True			biological_process											owl:Class	
GO:0001324	biolink:NamedThing	obsolete age-dependent response to oxidative stress involved in chronological cell aging	OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) occurring in non-dividing cells as they age as a result of oxidative stress, where the change varies according to the age of the cell or organism.	tmpzr1t_l9r_go_relaxed.owl	age-dependent response to oxidative stress during chronological cell aging|age-dependent response to oxidative stress during chronological cell ageing	https://github.com/geneontology/go-ontology/issues/18632				This term was obsoleted because it represent an assay - how long the cell lives -, not a true biological process.	GO:0044838|GO:0090398				True			biological_process											owl:Class	
GO:1905714	biolink:NamedThing	obsolete mitochondrial calcium release involved in regulation of presynaptic cytosolic calcium ion concentration	OBSOLETE. Any mitochondrial calcium release that is involved in regulation of presynaptic cytosolic calcium ion concentration.	tmpzr1t_l9r_go_relaxed.owl	mitochondrial calcium release involved in regulation of presynaptic cytosolic calcium levels|calcium ion transmembrane export from mitochondrion involved in regulation of presynaptic cytosolic calcium levels|calcium ion transmembrane export from mitochondrion involved in regulation of presynaptic cytosolic calcium ion concentration					This term was obsoleted at the TermGenie Gatekeeper stage.		dos	2016-11-23T15:56:01Z		True			biological_process											owl:Class	
GO:0019021	biolink:NamedThing	obsolete DNA viral genome	OBSOLETE. A viral genome composed of deoxyribonucleic acid.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it does not represent a GO cellular component.					True			cellular_component											owl:Class	
GO:0015263	biolink:NamedThing	obsolete amine/amide/polyamine channel activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	amine/amide/polyamine channel activity					This term was made obsolete because it represents three molecular functions.	GO:0015203|GO:0005275|GO:0042887				True			molecular_function											owl:Class	
GO:0016569	biolink:NamedThing	obsolete covalent chromatin modification	OBSOLETE. The alteration of DNA or protein in chromatin by the covalent addition or removal of chemical groups.	tmpzr1t_l9r_go_relaxed.owl	chromatin modification	https://github.com/geneontology/go-ontology/issues/22062				This term was obsoleted because it represents a molecular function.					True			biological_process											owl:Class	
GO:0000194	biolink:NamedThing	obsolete inactivation of MAPK (pseudohyphal growth)	OBSOLETE. Downregulation of MAP kinase activity in the context of regulating pseudohyphal or invasive growth.	tmpzr1t_l9r_go_relaxed.owl	inactivation of MAPK (pseudohyphal growth)					This term was made obsolete because it is a gene product specific term.					True			biological_process											owl:Class	
GO:0052014	biolink:NamedThing	obsolete catabolism by symbiont of host protein	OBSOLETE. The chemical reactions and pathways performed by an organism resulting in the breakdown of protein macromolecules within the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	catabolism by organism of host protein	https://github.com/geneontology/go-ontology/issues/21469				This term was obsoleted because it represents a molecular function.					True			biological_process											owl:Class	
GO:0097299	biolink:NamedThing	obsolete cysteine-type endopeptidase activity involved in plant-type hypersensitive response	OBSOLETE. Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile, and contributing to plant-type hypersensitive response, the rapid, localized death of plant cells in response to invasion by a pathogen.	tmpzr1t_l9r_go_relaxed.owl	metacaspase activity involved in plant-type hypersensitive response					This term was obsoleted because it represents a GO-CAM model.		pr	2012-05-04T02:09:55Z		True			molecular_function											owl:Class	
GO:0021912	biolink:NamedThing	obsolete regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification	OBSOLETE. Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that results the commitment of a cell to become a motor neuron in the ventral spinal cord.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it represents a GO-CAM model.	GO:0021520|GO:0006357				True			biological_process											owl:Class	
GO:0045784	biolink:NamedThing	obsolete positive regulation of calcium in ER	OBSOLETE. Any process that increases the concentration of calcium in the ER.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of calcium in ER					This term was made obsolete because the term name is ambiguous and as a result, the term was incorrectly placed in the ontology (it was a descendant of 'protein transport').	GO:0005783|GO:0006874				True			biological_process											owl:Class	
GO:0033159	biolink:NamedThing	obsolete negative regulation of protein import into nucleus, translocation	OBSOLETE. Any process that stops, prevents or reduces the vectorial transfer of a protein from the cytoplasm into the nucleus, across the nuclear membrane.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of protein import into cell nucleus, translocation					This term has been obsoleted because it represents a substep of the parent (GO:0006606 protein import into nucleus), has been incorrectly used.					True			biological_process											owl:Class	
GO:0015283	biolink:NamedThing	obsolete apoptogenic cytochrome c release channel activity	OBSOLETE. This term was not defined before being made obsolete.	tmpzr1t_l9r_go_relaxed.owl	Bcl-2|apoptogenic cytochrome c release channel activity					This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0036283	biolink:NamedThing	obsolete positive regulation of transcription factor import into nucleus in response to oxidative stress	OBSOLETE. Any process that activates or increases the frequency, rate or extent of the movement of a transcription factor from the cytoplasm to the nucleus under conditions of oxidative stress.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of transcription factor import into nucleus in response to hydrogen peroxide					The reason for obsoletion is that there is no distinct pathway to import transcription factors into the nucleus.	GO:0042307|GO:0034599	bf	2012-07-11T01:46:10Z		True			biological_process											owl:Class	
GO:0044150	biolink:NamedThing	obsolete development of host on or near symbiont surface	OBSOLETE. The progression of an organism from an initial condition to a later condition, occurring on or near the exterior of its symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	development of organism on or near symbiont surface					The reason for obsoletion is this term represents both a process and a component.		jl	2009-08-06T03:15:52Z		True			biological_process											owl:Class	
GO:0100047	biolink:NamedThing	obsolete negative regulation of inositol biosynthetic process by transcription from RNA polymerase II promoter	OBSOLETE. Any transcription from RNA polymerase II promoter process that negatively regulates inositol biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it represents a GO-CAM model.		cjm	2015-04-02T04:13:19Z		True			biological_process											owl:Class	
GO:0016511	biolink:NamedThing	obsolete endothelin-converting enzyme activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	endothelin-converting enzyme activity			GO:0004222		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:1901573	biolink:NamedThing	obsolete chemical substance catabolic process	OBSOLETE. The chemical reactions and pathways resulting in the breakdown of chemical substance.	tmpzr1t_l9r_go_relaxed.owl	chemical substance catabolism|chemical substance degradation|chemical substance catabolic process|chemical substance breakdown					This term was obsoleted at the TermGenie Gatekeeper stage.		pr	2012-11-04T18:10:36Z		True			biological_process											owl:Class	
GO:0052563	biolink:NamedThing	obsolete negative regulation by organism of symbiont immune response	OBSOLETE. Any process by which an organism stops, prevents, or reduces the frequency, rate or extent of the immune response of the symbiont organism; the immune response is any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	negative regulation by organism of symbiont immune response					This term was made obsolete because it does not represent a real biological process.					True			biological_process											owl:Class	
GO:0090020	biolink:NamedThing	obsolete regulation of transcription involved in posterior neural plate formation	OBSOLETE. Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter contributing to the formation of the posterior neural plate.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it represents a GO-CAM model.	GO:0090018|GO:0006357	tb	2009-07-29T11:39:29Z		True			biological_process											owl:Class	
GO:0019018	biolink:NamedThing	obsolete bipartite viral genome	OBSOLETE. A segmented viral genome consisting of two sub-genomic nucleic acids but each nucleic acid is packaged into a different virion.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it does not represent a GO cellular component.					True			cellular_component											owl:Class	
GO:0003780	biolink:NamedThing	obsolete actin cross-linking activity	OBSOLETE. Interacting selectively with two actin filaments to anchor them together.	tmpzr1t_l9r_go_relaxed.owl	actin cross-linking activity					This term was made obsolete because it represents a combination of molecular functions.	GO:0051015|GO:0030674				True			molecular_function											owl:Class	
GO:0016808	biolink:NamedThing	obsolete proprotein convertase activity	OBSOLETE. Was not defined before being made obsolete.	tmpzr1t_l9r_go_relaxed.owl	proprotein convertase activity			GO:0004252		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0050426	biolink:NamedThing	obsolete peptidyl-glycinamidase activity	OBSOLETE. Catalysis of the reaction: H2O + peptidyl-glycinamide = glycinamide + peptide. Cleavage of C-terminal glycinamide from a polypeptide.	tmpzr1t_l9r_go_relaxed.owl	carboxamidopeptidase activity|carboxyamidase activity|peptidyl-glycinamidase activity|peptidyl amino acid amide hydrolase activity|peptidyl carboxyamidase activity|peptidyl carboxy-amidase activity			GO:0008242		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0004988	biolink:NamedThing	obsolete mu-opioid receptor activity	OBSOLETE. Combining with an opioid to initiate a change in cell activity, with the pharmacological characteristics of mu-opioid receptors, including high affinity for enkephalins and beta-endorphin but low affinity for dynorphins.	tmpzr1t_l9r_go_relaxed.owl	mu-opioid receptor activity				Wikipedia:Mu_Opioid_receptor	This term was made obsolete because the receptor is defined based on its pharmacological properties.	GO:0038046|GO:0038047|GO:0004979				True			molecular_function											owl:Class	
GO:0052480	biolink:NamedThing	obsolete negative regulation by organism of defense-related symbiont jasmonic acid-mediated signal transduction pathway	OBSOLETE. Any process by which an organism stops, prevents, or reduces the frequency, rate or extent of symbiont jasmonic acid-mediated signal transduction pathways during the symbiont defense response. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	negative regulation by organism of defense-related symbiont jasmonic acid-mediated signal transduction pathway|negative regulation by organism of defense-related symbiont JA-mediated signal transduction pathway					This term was made obsolete because it does not represent a real biological process.					True			biological_process											owl:Class	
GO:1990800	biolink:NamedThing	obsolete meiotic APC-fizzy-related complex	OBSOLETE. An anaphase promoting complex bound to a fizzy-related family APC activator that regulates meiotic exit by activating the APC/C to target meiotic cyclins for destruction during meiosis.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted at the TermGenie Gatekeeper stage.		al	2015-07-16T10:37:05Z		True			cellular_component											owl:Class	
GO:0052308	biolink:NamedThing	obsolete pathogen-associated molecular pattern dependent modulation by organism of innate immune response in other organism involved in symbiotic interaction	OBSOLETE. Any process that involves recognition of a pathogen-associated molecular pattern, and by which an organism modulates the frequency, rate or extent of the innate immune response, the first line of defense against infection, of a second organism, where the two organisms are in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	pathogen-associated molecular pattern dependent modulation by organism of innate immunity in other organism during symbiotic interaction|pathogen-associated molecular pattern dependent modulation by organism of innate immunity in other organism involved in symbiotic interaction					This term was obsoleted because it has been misused.	GO:0002752|GO:0052034|GO:0002221				True			biological_process											owl:Class	
GO:0016988	biolink:NamedThing	obsolete transcription initiation factor antagonist activity	OBSOLETE. The function of binding to a transcription factor and stopping, preventing or reducing the rate of its transcriptional activity.	tmpzr1t_l9r_go_relaxed.owl	transcription initiation factor antagonist activity|transcriptional initiation factor antagonist activity					This term was obsoleted because its definition was vague and apparently broader in scope than the name of the term suggested it was intended to be.					True			molecular_function											owl:Class	
GO:0100052	biolink:NamedThing	obsolete negative regulation of G1/S transition of mitotic cell cycle by transcription from RNA polymerase II promoter	OBSOLETE. Any transcription from RNA polymerase II promoter process that negatively regulates G1/S transition of mitotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it represents a GO-CAM model.		cjm	2015-04-02T04:13:19Z		True			biological_process											owl:Class	
GO:0039569	biolink:NamedThing	obsolete suppression by virus of host STAT2 activity by positive regulation of STAT2 catabolic process	OBSOLETE. Any process in which a virus stops, prevents, or reduces the activity of host STAT2 (signal transducer and activator of transcription-2) by promoting the ubiquitin-dependent degradation of STAT2, mediated by the proteasome.	tmpzr1t_l9r_go_relaxed.owl	targeting STAT2 for proteasome-mediated degradation|promotion by virus of proteosome-dependent STAT2 degradation|suppression by virus of host STAT2 activity by positive promotion of STAT2 proteasome-mediated degradation					The reason for obsoleting this term is that it is too specific. The exact molecular roles of the individual proteins should be captured separately.		bf	2012-03-12T04:43:44Z		True			biological_process											owl:Class	
GO:0052185	biolink:NamedThing	obsolete modification of structure of other organism involved in symbiotic interaction	OBSOLETE. The process in which an organism effects a change in an anatomical part or cellular component of a second organism, where the two organisms are in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	modification of structure of other organism during symbiotic interaction					This term was obsoleted because it represents an unnecessary grouping class.					True			biological_process											owl:Class	
GO:0005013	biolink:NamedThing	obsolete neurotrophin TRK receptor activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	neurotrophin TRK receptor activity					This term was made obsolete because it represents a gene product.	GO:0007165|GO:0019838|GO:0043121|GO:0004714				True			molecular_function											owl:Class	
GO:0005800	biolink:NamedThing	obsolete COPII vesicle	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	COPII vesicle					This term was made obsolete as part of a general reorganization of vesicle and vesicle coat terms; its position in the ontology suggested that a new term was required.	GO:0030134				True			cellular_component											owl:Class	
GO:0007261	biolink:NamedThing	obsolete JAK-induced STAT protein dimerization	OBSOLETE. The formation of a dimer of two STAT proteins (Signal Transducers and Activators of Transcription) following their activation by members of the janus activated kinase (JAK) family of tyrosine kinases.	tmpzr1t_l9r_go_relaxed.owl	JAK-induced STAT protein dimerization					This term was made obsolete because it is ambiguous, and protein dimerization is represented by molecular function terms.	GO:0007260|GO:0046983				True			biological_process											owl:Class	
GO:0039546	biolink:NamedThing	obsolete suppression by virus of host MAVS activity by MAVS proteolysis	OBSOLETE. The chemical reactions and pathways performed by a virus resulting in the hydrolysis of the host MAVS (mitochondrial inhibitor of viral signaling) protein by cleavage of peptide bonds, thereby inhibiting the host innate immune response. For example, MAVS harbors a C-terminal transmembrane domain that targets it to the mitochondrial outer membrane; cleavage within this domain removes MAVS from the membrane, thus preventing it from signaling.	tmpzr1t_l9r_go_relaxed.owl	viral protease cleavage of MAVS					The reason for obsoleting this term is that it is too specific. The exact molecular roles of the individual proteins should be captured separately.		bf	2012-01-19T02:49:44Z		True			biological_process											owl:Class	
GO:0120038	biolink:NamedThing	obsolete plasma membrane bounded cell projection part	OBSOLETE. Any constituent part of a plasma membrane bounded cell projection, a prolongation or process extending from a cell, e.g. a cilium or axon.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/13298					GO:0120025	krc	2017-04-28T17:20:43Z		True			cellular_component											owl:Class	
GO:0003788	biolink:NamedThing	obsolete actin monomer sequestering activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	actin monomer sequestering activity			GO:0042989		This term was made obsolete because sequestering is a process, not an activity.					True			molecular_function											owl:Class	
GO:0001627	biolink:NamedThing	obsolete leucine-rich G-protein receptor-like receptor activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	LGR-like receptor|leucine-rich G protein receptor-like receptor activity|leucine-rich G-protein receptor-like receptor activity					This term was made obsolete because it represents a gene product, was not defined, and is named based on protein features.					True			molecular_function											owl:Class	
GO:0008500	biolink:NamedThing	obsolete glycine-, glutamate-, thienylcyclohexylpiperidine binding	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	glycine-, glutamate-, thienylcyclohexylpiperidine binding					This term was made obsolete because it is a conglomeration of three terms.	GO:0016595|GO:0016596|GO:0016594				True			molecular_function											owl:Class	
GO:0045826	biolink:NamedThing	obsolete positive regulation of intermediate filament polymerization and/or depolymerization	OBSOLETE. Any process that activates or increases the frequency, rate or extent of intermediate filament polymerization and/or depolymerization.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of intermediate filament polymerization and/or depolymerization					This term was made obsolete because it has been split.	GO:0030841|GO:0030844				True			biological_process											owl:Class	
GO:0043275	biolink:NamedThing	obsolete glutamate carboxypeptidase II activity	OBSOLETE. Catalysis of the reaction: N-acetyl-L-Asp-L-Glu + H2O = N-acetyl-L-Asp + L-Glu.	tmpzr1t_l9r_go_relaxed.owl	glutamate carboxypeptidase II activity|prostate-specific membrane antigen|PSMA|folate hydrolase activity|pteroylpolyglutamic acid hydrolase activity|N-acetylated-alpha-linked-amino dipeptidase activity|N-acetylated-gamma-linked-acidic dipeptidase activity|pteroylpoly-gamma-glutamate hydrolase activity|NAALA dipeptidase activity|prostrate-specific membrane antigen|microsomal gamma-glutamyl carboxypeptidase|pteroylpolyglutamate hydrolase activity|PSM antigen|N-acetylated-gamma-linked-acidic dipeptidase (NAALADase)|pteroylpolygammaglutamyl hydrolase activity|acetylaspartylglutamate dipeptidase activity|pteroylpoly-gamma-glutamate carboxypeptidase activity|folylpolyglutamate hydrolase activity|mGCP|N-acetylated alpha-linked acidic dipeptidase activity|rat NAAG peptidase|NAALADase activity|membrane glutamate carboxypeptidase			GO:0004181		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0005206	biolink:NamedThing	obsolete heparin sulfate proteoglycan	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	heparin sulphate proteoglycan|heparin sulfate proteoglycan					This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0039577	biolink:NamedThing	obsolete suppression by virus of host JAK1 activity by negative regulation of JAK1 phosphorylation	OBSOLETE. Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host JAK1 (Janus Kinase 1) activity by stopping, preventing or reducing tyrosine phosphorylation of JAK1 and thereby activation of JAK1.	tmpzr1t_l9r_go_relaxed.owl						The reason for obsoleting this term is that it is too specific. The exact molecular roles of the individual proteins should be captured separately.		bf			True			biological_process											owl:Class	
GO:0009461	biolink:NamedThing	obsolete cytochrome c	OBSOLETE. A cytochrome containing heme bound to the protein by one or, more (commonly two) thioether bonds involving sulfhydryl groups of cysteine residues.	tmpzr1t_l9r_go_relaxed.owl				GO:0008121		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0052499	biolink:NamedThing	obsolete pathogen-associated molecular pattern dependent modulation by organism of symbiont innate immunity	OBSOLETE. This term was not defined before being made obsolete.	tmpzr1t_l9r_go_relaxed.owl	pathogen-associated molecular pattern dependent modulation by organism of symbiont innate immunity					This term was made obsolete because it does not represent a real biological process.					True			biological_process											owl:Class	
GO:0039510	biolink:NamedThing	obsolete suppression by virus of host ATP-dependent RNA helicase activity	OBSOLETE. Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host ATP-dependent RNA helicase activity.	tmpzr1t_l9r_go_relaxed.owl	down-regulation by virus of host ATP-dependent RNA helicase activity|inhibition by virus of host ATP-dependent RNA helicase activity|negative regulation by virus of host ATP-dependent RNA helicase activity|downregulation by virus of host ATP-dependent RNA helicase activity	https://github.com/geneontology/go-ontology/issues/21740				This term was obsoleted because it represents a molecular function.		bf	2011-06-16T02:11:00Z		True			biological_process											owl:Class	
GO:0017088	biolink:NamedThing	obsolete X-Pro dipeptidyl-peptidase activity	OBSOLETE. Catalysis of the hydrolysis of the terminal bond of Xaa-Pro-Xaa motifs to release unblocked, N-terminal dipeptides from substrates including Ala-Pro-para-nitroanilide and (sequentially, at the second, fourth and sixth bonds) of the motif Tyr-Pro-Phe-Pro-Gly-Pro-Ile.	tmpzr1t_l9r_go_relaxed.owl	X-Pro dipeptidyl-peptidase activity|Xaa-Pro dipeptidyl-peptidase activity|X-prolyl dipeptidyl peptidase activity|PepX|X-prolyl dipeptidyl aminopeptidase activity			GO:0008239		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0003840	biolink:NamedThing	obsolete gamma-glutamyltransferase activity	OBSOLETE. Catalysis of the reaction: (5-L-glutamyl)-peptide + an amino acid = peptide + 5-L-glutamyl-amino acid.	tmpzr1t_l9r_go_relaxed.owl	alpha-glutamyl transpeptidase activity|L-gamma-glutamyltransferase activity|gamma-glutamyl transpeptidase activity|glutamyl transpeptidase activity|(5-L-glutamyl)-peptide:amino-acid 5-glutamyltransferase activity|L-glutamyltransferase activity|gamma-GPT|L-gamma-glutamyl transpeptidase activity|gamma-GT|gamma-GTP|gamma-glutamyl peptidyltransferase activity				KEGG_REACTION:R04159|MetaCyc:GAMMA-GLUTAMYLTRANSFERASE-RXN|EC:2.3.2.2	This term was obsoleted because it does not correspond to a physiological reaction. Usage comment: The gene family commonly referred to as gamma-glutamyl transferases (GGT) catalyze hydrolysis of gamma-glutamyl bonds in gamma-glutamyl compounds such as glutathione. In a test tube one can set up conditions in which the enzyme will transfer the gamma-glutamyl portion of the substrate to an acceptor molecule, but this requires non-physiologic conditions, including millmolar concentrations of an acceptor such as glygly. This reaction is used in assays to detect the presence of the enzyme, but is not a physiological function of members of the GGT family (PMC4388159), which should be annotated to a suitable hydrolysis term instead (e.g. glutathione hydrolase activity).	GO:0036374				True			molecular_function											owl:Class	
GO:0100060	biolink:NamedThing	obsolete negative regulation of SREBP signaling pathway by DNA binding	OBSOLETE. Any DNA binding that negatively regulates SREBP signaling pathway.	tmpzr1t_l9r_go_relaxed.owl						The reason for obsoletion is that this term should be represented by a GO-CAM model.		cjm	2015-04-02T04:13:19Z		True			molecular_function											owl:Class	
GO:0019804	biolink:NamedThing	obsolete quinolinate synthetase complex	OBSOLETE. A heterodimer which acts as a quinolinate synthetase; quinolinate synthetase B (L-aspartate oxidase) catalyzes the oxidation of L-aspartate to L-iminoaspartate; quinolinate synthetase A condenses L-imidoaspartate and dihydroxyacetone to quinolinate.	tmpzr1t_l9r_go_relaxed.owl	quinolinate synthetase complex					This term was made obsolete because there is no evidence that a physical complex forms; although the phrase "quinolinate synthetase complex" is occasionally used in the literature, it refers to two enzymes that act as monomers.	GO:0008743|GO:0008987				True			cellular_component											owl:Class	
GO:0044713	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0005805	biolink:NamedThing	obsolete ER-Golgi transport vesicle	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	ER-Golgi transport vesicle					This term was made obsolete as part of a general reorganization of vesicle and vesicle coat terms; its position in the ontology suggested that a new term was required.	GO:0030134				True			cellular_component											owl:Class	
GO:0017107	biolink:NamedThing	obsolete anion exchanger adaptor activity	OBSOLETE. The binding activity of a molecule that brings together an anion exchanger and one or more other molecules, permitting them to function in a coordinated way.	tmpzr1t_l9r_go_relaxed.owl						The term was made obsolete because it referred to an interaction of an anion transporter with the AP1 adaptor by which it is probably transported, see: PMID:22744004; PMID:20833140; ie the adaptor does not specifically target an anion adaptor.					True			molecular_function											owl:Class	
GO:0016187	biolink:NamedThing	obsolete synaptic vesicle internalization	OBSOLETE. Internalization of the contents of a synaptic vesicle into the postsynaptic membrane following endocytosis.	tmpzr1t_l9r_go_relaxed.owl	synaptic vesicle internalization					This term was made obsolete because it was wrongly defined.	GO:0016192				True			biological_process											owl:Class	
GO:0030568	biolink:NamedThing	obsolete plasmin inhibitor activity	OBSOLETE. Stops, prevents or reduces the activity of the serine endopeptidase plasmin.	tmpzr1t_l9r_go_relaxed.owl	plasmin inhibitor activity			GO:0004867		This term was made obsolete because it represents a regulator of an obsolete molecular function.					True			molecular_function											owl:Class	
GO:0006854	biolink:NamedThing	obsolete ATP/ADP exchange	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	ATP/ADP exchange			GO:0005471		This term was made obsolete because it represents a molecular function and not a biological process.					True			biological_process											owl:Class	
GO:0097235	biolink:NamedThing	obsolete positive regulation of fatty acid beta-oxidation by positive regulation of transcription from RNA polymerase II promoter	OBSOLETE. Any process that activates or increases the frequency, rate or extent of fatty acid beta-oxidation by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it represents a GO-CAM model.		pr	2012-02-01T05:07:12Z		True			biological_process											owl:Class	
GO:0004716	biolink:NamedThing	obsolete signal transducer, downstream of receptor, with protein tyrosine kinase activity	OBSOLETE. Conveys a signal from an upstream receptor or intracellular signal transducer by catalysis of the reaction: ATP + a protein-L-tyrosine = ADP + a protein-L-tyrosine phosphate.	tmpzr1t_l9r_go_relaxed.owl	receptor signaling protein tyrosine kinase activity|receptor signalling protein tyrosine kinase activity	https://github.com/geneontology/go-ontology/issues/14232			EC:2.7.10.-	This term was obsoleted because it was not clearly defined.					True			molecular_function											owl:Class	
GO:0016945	biolink:NamedThing	obsolete RNA polymerase III transcription elongation factor activity	OBSOLETE. Any activity that modulates the rate of transcription elongation, the addition of ribonucleotides to an RNA molecule catalyzed by RNA polymerase III following transcription initiation.	tmpzr1t_l9r_go_relaxed.owl	Pol III transcription elongation factor activity|RNA polymerase III transcription elongation factor activity					This term was obsoleted because it is essentially identical to a Process term (specifically the Biological Process term which has been selected as a term to consider for reannotation), i.e. it is defined only in terms of the process it acts in and it does NOT convey any information about the molecular nature of the function or whether the function is based on binding DNA, on interacting with other proteins, or some other mechanism. To transfer all annotations without review, the BP term indicated is considered to be equivalent and thus the only appropriate destination for all annotations. To reannotate to a MF term, you will probably need to revisit the original literature or other primary data because this "MF" term was not defined in terms of mechanism of action and there are multiple possibilities in the revised MF structure. In reannotation, please also consider descendent terms of the suggested MF terms as a more specific term may be more appropriate than the MF terms indicated. Please be aware that you may wish to request a new term if the mechanism of action of this gene product is not yet represented or if you are annotating for an RNAP different than one for which there is a specific suggested term. Also note that if there is no information about how the gene product acts, it may be appropriate to annotate to the root term for molecular_function.	GO:0006385				True			molecular_function											owl:Class	
GO:0009477	biolink:NamedThing	obsolete cytochrome c1	OBSOLETE. A cytochrome c that is an integral component of the mitochondrial respiratory complex III. Functions as an electron donor to cytochrome c.	tmpzr1t_l9r_go_relaxed.owl	cytochrome c1			GO:0004129		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0008550	biolink:NamedThing	obsolete tubulin GTPase activity	OBSOLETE. Catalysis of the reaction: GTP + H2O = GDP + phosphate. An intrinsic activity of alpha-tubulin involved in tubulin folding, division plane formation in prokaryotic cells and others.	tmpzr1t_l9r_go_relaxed.owl	tubulin GTPase activity					This term was made obsolete because it represents a gene product.	GO:0003924|GO:0007021				True			molecular_function											owl:Class	
GO:0008164	biolink:NamedThing	obsolete organophosphorus resistance	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	organophosphorus resistance			GO:0046683		This term was made obsolete because 'resistance' implies a phenotype rather than a biological process.					True			biological_process											owl:Class	
GO:0100030	biolink:NamedThing	obsolete regulation of histone acetylation by transcription from RNA polymerase II promoter	OBSOLETE. Any transcription from RNA polymerase II promoter process that regulates histone acetylation.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it describes a process that does not exist.		cjm	2015-04-02T04:13:19Z		True			biological_process											owl:Class	
GO:0051815	biolink:NamedThing	obsolete migration in other organism involved in symbiotic interaction	OBSOLETE. The directional movement of an organism from one place to another within a second organism, where the two organisms are in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	migration within other organism during symbiotic interaction|migration in other organism during symbiotic interaction					This term was obsoleted because it represented both a process and a location.					True			biological_process											owl:Class	
GO:0052531	biolink:NamedThing	obsolete positive regulation by organism of defense-related symbiont calcium ion flux	OBSOLETE. Any process by which an organism activates, maintains or increases the frequency, rate or extent of fluxes of calcium ions that occur as part of the defense response of a host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	positive regulation by organism of defense-related symbiont calcium ion flux|positive regulation by organism of defense-related symbiont Ca2+ flux					This term was made obsolete because it does not represent a real biological process.					True			biological_process											owl:Class	
GO:1900830	biolink:NamedThing	obsolete D-tyrosine biosynthetic process	OBSOLETE. The chemical reactions and pathways resulting in the formation of D-tyrosine.	tmpzr1t_l9r_go_relaxed.owl	D-tyrosine biosynthesis|D-tyrosine synthesis|D-tyrosine anabolism|D-tyrosine formation	https://github.com/geneontology/go-ontology/issues/20583				This term was obsoleted because there is no evidence that this process exists.		se	2012-06-06T09:27:31Z		True			biological_process											owl:Class	
GO:0051845	biolink:NamedThing	obsolete passive evasion of symbiont immune response	OBSOLETE. Any mechanism of immune avoidance that does not directly interfere with the symbiont immune system. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	passive immune evasion|passive evasion of symbiont immune response					This term was made obsolete because it does not represent a real process that exists in nature.					True			biological_process											owl:Class	
GO:0052172	biolink:NamedThing	obsolete metabolism by symbiont of host cell wall cellulose	OBSOLETE. The chemical reactions and pathways performed by an organism involving cellulose in the cell wall of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/21469				This term was obsoleted because it represents a molecular function.					True			biological_process											owl:Class	
GO:0039570	biolink:NamedThing	obsolete suppression by virus of host STAT2 activity by negative regulation of STAT protein import into nucleus	OBSOLETE. Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host STAT2 (signal transducer and activator of transcription-2) activity by retaining STAT2 in the cytoplasm, so STAT2 is unable to translocate to the nucleus to activate transcription of its target genes.	tmpzr1t_l9r_go_relaxed.owl	cytoplasmic sequestration of STAT2|cytoplasmic sequestering of STAT2					The reason for obsoleting this term is that it is too specific. The exact molecular roles of the individual proteins should be captured separately.		bf	2012-03-12T04:46:49Z		True			biological_process											owl:Class	
GO:0007180	biolink:NamedThing	obsolete transforming growth factor beta ligand binding to type II receptor	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	TGF-beta ligand binding to type II receptor|transforming growth factor beta ligand binding to type II receptor|TGFbeta ligand binding to type II receptor					This term was made obsolete because it represents a function.	GO:0005160|GO:0050431|GO:0005026				True			biological_process											owl:Class	
GO:0005071	biolink:NamedThing	obsolete transmembrane receptor protein serine/threonine kinase signaling protein activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	transmembrane receptor protein serine/threonine kinase signaling protein activity|transmembrane receptor protein serine/threonine kinase signalling protein activity					This term was made obsolete because the meaning of the term is ambiguous and it incorporates process information.	GO:0007178|GO:0035556				True			molecular_function											owl:Class	
RO:0002013	biolink:NamedThing	has regulatory component activity		tmpzr1t_l9r_go_relaxed.owl					RO:0002013									external									has_regulatory_component_activity			
GO:0008371	biolink:NamedThing	obsolete biological process	OBSOLETE. These are terms that have been removed from the active process ontology.	tmpzr1t_l9r_go_relaxed.owl						This term was made obsolete because it is unnecessary in the OBO flat file format.					True			biological_process											owl:Class	
GO:0071523	biolink:NamedThing	obsolete TIR domain-mediated complex assembly	OBSOLETE. A process of protein complex assembly in which the arrangement and bonding together of the set of components that form the protein complex is mediated by a TIR domain interaction.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it represented a molecular function (binding), not a biological process. The term represented a domain involved in protein-protein interactions, but no necessarily the process of assembling a complex.		mah	2010-01-07T02:11:47Z		True			biological_process											owl:Class	
GO:0045233	biolink:NamedThing	obsolete natural killer cell receptor activity	OBSOLETE. A receptor found on the surface of natural killer cells which binds Class I MHC antigens and is required for activation of NK activity. It belongs to the Ly49i family.	tmpzr1t_l9r_go_relaxed.owl	Ly49i|NK cell receptor activity|natural killer cell receptor activity					This term was made obsolete because the receptor is defined based on its cellular expression pattern, and the definition is inaccurate: receptors on natural killer cells can either activate or inhibit natural killer (NK) cell-mediated cytotoxicity.	GO:0002769|GO:0030101|GO:0004888				True			molecular_function											owl:Class	
GO:0075206	biolink:NamedThing	obsolete positive regulation by host of symbiont cAMP-mediated signal transduction	OBSOLETE. Any process in which the host organism activates, maintains or increases the frequency, rate or extent of cAMP-mediated signal transduction in the symbiont organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	positive regulation by host of symbiont cAMP-mediated signaling					The reason for obsoletion is that there is no evidence that the host can modulate or regulate a symbiont's signal transduction pathway.					True			biological_process											owl:Class	
GO:1903153	biolink:NamedThing	obsolete ferrous iron transmembrane transporter activity involved in ferrous iron import into cell	OBSOLETE. Any ferrous iron transmembrane transporter activity that is involved in ferrous iron import into cell.	tmpzr1t_l9r_go_relaxed.owl	ferrous iron transmembrane transporter activity involved in ferrous ion import into cell|ferrous iron transmembrane transporter activity involved in ferrous iron import into cell					This term was obsoleted at the TermGenie Gatekeeper stage.		dos	2014-07-09T11:55:53Z		True			molecular_function											owl:Class	
GO:1990132	biolink:NamedThing	obsolete release of misfolded protein from chaperone	OBSOLETE. The release of misfolded proteins that are being held by the chaperone heat shock protein (Hsp) and targeting them for destruction by the Ub-proteasome machinery.	tmpzr1t_l9r_go_relaxed.owl	release of misfolded protein from chaperone					This term was obsoleted at the TermGenie Gatekeeper stage.		rb	2013-06-25T21:56:37Z		True			biological_process											owl:Class	
GO:0010843	biolink:NamedThing	obsolete promoter binding	OBSOLETE. Binding to a regulatory region composed of the transcription start site and binding sites for transcription factor complexes of the basal transcription machinery.	tmpzr1t_l9r_go_relaxed.owl	DNA binding, transcription promoter|promoter binding					This term was made obsolete because the word "promoter" is used ambiguously in the literature. It sometimes is used to refer specifically to the "core promoter" region recognized by the basal transcription machinery, and other times is used to refer to a larger regulatory region composed of the core promoter and also the regulatory region adjacent (proximal) to the core promoter. The core promoter proximal region is typically recognized by "regulatory transcription factors", such as Gal4 in S. cerevisiae.	GO:0001046|GO:0000976				True			molecular_function											owl:Class	
GO:0071898	biolink:NamedThing	obsolete regulation of estrogen receptor binding	OBSOLETE. Any process that modulates the frequency, rate or extent of estrogen receptor binding, interacting selectively with a an estrogen receptor.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/19354				This term was obsoleted because it represents a molecular function.		mah	2010-09-15T02:48:49Z		True			biological_process											owl:Class	
GO:0043948	biolink:NamedThing	obsolete induction by symbiont of host catalytic activity	OBSOLETE. Any process in which the symbiont activates, maintains or increases the frequency, rate or extent of host enzyme activity. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	upregulation by symbiont of host enzyme activity|up regulation by symbiont of host enzyme activity|positive regulation by symbiont of host catalytic activity|activation of host enzyme activity|activation by symbiont of host enzyme activity|up-regulation by symbiont of host enzyme activity|positive regulation by symbiont of host enzyme activity	https://github.com/geneontology/go-ontology/issues/21740				This term was obsoleted because it represents a molecular function.					True			biological_process											owl:Class	
GO:2000499	biolink:NamedThing	obsolete negative regulation of induction of apoptosis in response to chemical stimulus	OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of induction of apoptosis in response to chemical stimulus.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of induction of apoptosis in response to chemical substance|negative regulation of induction of apoptosis in response to chemical stimulus					This term was made obsolete because it is ill-defined.		yaf	2011-03-18T02:35:44Z		True			biological_process											owl:Class	
GO:1990372	biolink:NamedThing	obsolete process resulting in tolerance to organic acid	OBSOLETE. A response that results in a state of tolerance to organic acid.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it does not represent a clear process.		tt	2014-04-23T22:34:12Z		True			biological_process											owl:Class	
GO:0052225	biolink:NamedThing	obsolete energy taxis on or near other organism involved in symbiotic interaction	OBSOLETE. The directed movement of a motile cell or organism on or near a second organism in response to physical parameters involved in energy generation, such as light, oxygen, and oxidizable substrates, where the two organisms are in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	energy taxis on or near other organism during symbiotic interaction					This term was obsoleted because it represents both a process and a location.					True			biological_process											owl:Class	
GO:1990480	biolink:NamedThing	obsolete geranyl diphosphate synthase	OBSOLETE. Catalyzes the condensation of dimethylallyl diphosphate and isopentenyl diphosphate to geranyl diphosphate, the key precursor of monoterpene biosynthesis.	tmpzr1t_l9r_go_relaxed.owl				GO:0004161		This term was obsoleted at the TermGenie Gatekeeper stage.		tt	2014-09-10T01:14:17Z		True			molecular_function											owl:Class	
GO:0055114	biolink:NamedThing	obsolete oxidation-reduction process	OBSOLETE. A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons.	tmpzr1t_l9r_go_relaxed.owl	oxidation reduction|oxidoreductase process	https://github.com/geneontology/go-ontology/issues/20250				This term was obsoleted because it represents a molecular function.					True			biological_process											owl:Class	
GO:0075207	biolink:NamedThing	obsolete negative regulation by host of symbiont cAMP-mediated signal transduction	OBSOLETE. Any process in which the host organism stops, prevents, or reduces the frequency, rate or extent of cAMP-mediated signal transduction in the symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	negative regulation by host of symbiont cAMP-mediated signaling					The reason for obsoletion is that there is no evidence that the host can modulate or regulate a symbiont's signal transduction pathway.					True			biological_process											owl:Class	
GO:0075020	biolink:NamedThing	obsolete calcium or calmodulin-mediated activation of appressorium formation	OBSOLETE. Any process that modulates the frequency, rate or extent of symbiont calcium or calmodulin-mediated signal transduction during appressorium formation on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	Ca2+ or calmodulin-mediated activation of appressorium formation|Ca++ or calmodulin-mediated activation of appressorium formation					This term was obsoleted because it represents a GO-CAM model.					True			biological_process											owl:Class	
GO:0030814	biolink:NamedThing	obsolete regulation of cAMP metabolic process	OBSOLETE. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate).	tmpzr1t_l9r_go_relaxed.owl	regulation of adenosine 3',5'-cyclophosphate metabolism|regulation of cyclic AMP metabolism|regulation of 3',5' cAMP metabolic process|regulation of cyclic AMP metabolic process|regulation of 3',5'-cAMP metabolic process|regulation of 3',5' cAMP metabolism|regulation of cAMP metabolism|regulation of 3',5'-cAMP metabolism|regulation of adenosine 3',5'-cyclophosphate metabolic process					The reason for obsoletion is that this term represents the regulation of a signaling pathway, not regulation of metabolism.					True			biological_process											owl:Class	
GO:0018337	biolink:NamedThing	obsolete enzyme active site formation via L-2',4',5'-topaquinone	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	enzyme active site formation via L-2',4',5'-topaquinone					This term was made obsolete because this process does not occur: the modification occurs before it can be an active site.					True			biological_process											owl:Class	
GO:0009490	biolink:NamedThing	obsolete mononuclear iron electron carrier	OBSOLETE. A mononuclear iron entity that serves as an electron acceptor and electron donor in an electron transport system.	tmpzr1t_l9r_go_relaxed.owl	mononuclear iron electron carrier			GO:0009055		This term was made obsolete because it refers to a class of gene products.					True			molecular_function											owl:Class	
GO:0018324	biolink:NamedThing	obsolete enzyme active site formation via L-cysteine sulfenic acid	OBSOLETE. The oxidation of peptidyl-cysteine to form peptidyl-L-cysteine sulfenic acid, found in the active site of NADH peroxidase, nitrile hydratase, and peptide methionine sulfoxide reductase.	tmpzr1t_l9r_go_relaxed.owl	enzyme active site formation via L-cysteine sulphenic acid	https://github.com/geneontology/go-ontology/issues/15594			RESID:AA0205	This term was obsoleted because it represents a reaction intermediate, not a biological process, see PMID:10964927 and PMID:9587003.					True			biological_process											owl:Class	
GO:0097469	biolink:NamedThing	obsolete cyclin-dependent protein tyrosine kinase activity	OBSOLETE. Catalysis of the reaction: ATP + a protein tyrosine = ADP + protein tyrosine phosphate. This reaction requires the binding of a regulatory cyclin subunit.	tmpzr1t_l9r_go_relaxed.owl	cyclin-dependent protein tyrosine kinase activity					This term was made obsolete because it was added in error; the specific activity it refers to has never been observed.		pr	2013-02-19T12:42:11Z		True			molecular_function											owl:Class	
GO:0008129	biolink:NamedThing	obsolete actinidain activity	OBSOLETE. Catalysis of the hydrolysis of proteins with broad specificity for peptide bonds, with preference for a residue bearing a large hydrophobic side chain at the P2 position. Does not accept Val at P1'.	tmpzr1t_l9r_go_relaxed.owl	proteinase A2 of actinidia chinensis|actinidia anionic protease activity|actinidin activity|actinidain activity			GO:0004197		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0006496	biolink:NamedThing	obsolete protein amino acid terminal N-glycosylation	OBSOLETE. The glycosylation of a nitrogen atom of a free alpha amino terminal of a peptide.	tmpzr1t_l9r_go_relaxed.owl	protein amino acid terminal N-glycosylation					This term was made obsolete because the term name is ambiguous.	GO:0006487|GO:0035629				True			biological_process											owl:Class	
GO:0004258	biolink:NamedThing	obsolete vacuolar carboxypeptidase Y	OBSOLETE. Catalysis of the release of a C-terminal amino acid with a broad specificity.	tmpzr1t_l9r_go_relaxed.owl	vacuolar carboxypeptidase Y					This term was made obsolete because it contains both component and function information.	GO:0004185|GO:0005773				True			molecular_function											owl:Class	
GO:1990279	biolink:NamedThing	obsolete negative regulation of MBF transcription factor activity	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of the transcription factor MBF.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of MBF transcription factor activity					This term was obsoleted at the TermGenie Gatekeeper stage.		al	2014-01-29T14:46:52Z		True			biological_process											owl:Class	
GO:0072463	biolink:NamedThing	obsolete detection of stimulus involved in meiotic spindle assembly checkpoint	OBSOLETE. The series of events in which information about whether spindle is correctly assembled and chromosomes are attached to the spindle is received and converted into a molecular signal, contributing to a meiotic spindle assembly checkpoint.	tmpzr1t_l9r_go_relaxed.owl	meiotic spindle assembly checkpoint sensor mechanism|sensing involved in meiotic spindle assembly checkpoint|meiotic spindle assembly checkpoint sensor process	https://github.com/geneontology/go-ontology/issues/20976				This term was obsoleted because it corresponds to a molecular function.		mah	2010-12-09T11:37:41Z		True			biological_process											owl:Class	
GO:0052476	biolink:NamedThing	obsolete negative regulation by organism of defense-related symbiont MAP kinase-mediated signal transduction pathway	OBSOLETE. Any process by which an organism stops, prevents, or reduces the frequency, rate or extent of symbiont MAP kinase-mediated signal transduction pathways during the symbiont defense response. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	negative regulation by organism of defense-related symbiont mitogen-activated protein kinase-mediated signal transduction pathway|negative regulation by organism of defense-related symbiont MAP kinase-mediated signal transduction pathway|suppression by organism of defense-related symbiont MAP kinase-mediated signal transduction pathway|negative regulation by organism of defense-related symbiont MAPK-mediated signal transduction pathway					This term was made obsolete because it does not represent a valid biological process that occurs in nature.					True			biological_process											owl:Class	
GO:0000258	biolink:NamedThing	obsolete isoleucine/valine:sodium symporter activity	OBSOLETE. Catalysis of the reaction: (isoleucine or valine)(out) + Na+(out) = (isoleucine or valine)(in) + Na+(in).	tmpzr1t_l9r_go_relaxed.owl	isoleucine/valine:sodium symporter activity					This term was made obsolete because it represents a multifunctional gene product.	GO:0015188|GO:0005304|GO:0005283				True			molecular_function											owl:Class	
GO:1990347	biolink:NamedThing	obsolete G*/A mismatch-specific adenine-DNA glycosylase activity	OBSOLETE. Catalysis of the removal of adenine misinserted into nascent strand opposite 8-oxoG in the template by adenine DNA glycosylase activity. The reaction leaves an apyrimidinic (AP) site.	tmpzr1t_l9r_go_relaxed.owl	G*/A mismatch-specific adenine-DNA glycosylase activity					This term was obsoleted at the TermGenie Gatekeeper stage.		al	2014-03-25T10:14:37Z		True			molecular_function											owl:Class	
GO:1900414	biolink:NamedThing	obsolete regulation of cytokinesis by regulation of transcription from RNA polymerase II promoter	OBSOLETE. A regulation of transcription from RNA polymerase II promoter that results in regulation of cytokinesis.	tmpzr1t_l9r_go_relaxed.owl								mah	2012-04-20T03:42:13Z		True			biological_process											owl:Class	
GO:0005645	biolink:NamedThing	obsolete RAN-binding protein	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	RAN-binding protein			GO:0031267		This term was made obsolete because it represents a single gene product and not a complex.					True			cellular_component											owl:Class	
GO:0003966	biolink:NamedThing	obsolete RNA-directed DNA polymerase, transposon encoded	OBSOLETE. Catalysis of RNA-template-directed extension of the 3'- end of a DNA strand by one deoxynucleotide at a time; cannot initiate a chain de novo.	tmpzr1t_l9r_go_relaxed.owl	RNA-directed DNA polymerase, transposon encoded			GO:0003964		This term was made obsolete because it does not represent a function distinct from its parent term 'RNA-directed DNA polymerase'.					True			molecular_function											owl:Class	
preceded_by	biolink:NamedThing	preceded by		tmpzr1t_l9r_go_relaxed.owl					BFO:0000062									external									preceded_by			
GO:0034187	biolink:NamedThing	obsolete apolipoprotein E binding	OBSOLETE. Binding to apolipoprotein E.	tmpzr1t_l9r_go_relaxed.owl	apolipoprotein E binding			GO:0034185		This term was made obsolete because it represents binding to an individual protein.					True			molecular_function											owl:Class	
GO:0005710	biolink:NamedThing	obsolete metaphase chromosome	OBSOLETE. A chromosome found in the cell during metaphase. Typically, sister chromatids are held together at their centromeres and chromosomes are covered with a large number of molecules, including ribonucleoproteins.	tmpzr1t_l9r_go_relaxed.owl	metaphase chromosome					This term was made obsolete because it is based on a temporal division of the cell cycle.	GO:0000793|GO:0000794				True			cellular_component											owl:Class	
GO:1990105	biolink:NamedThing	obsolete regulation of voltage-gated potassium channel activity	OBSOLETE. Any process that modulates the frequency, rate or extent of voltage-gated potassium channel activity.	tmpzr1t_l9r_go_relaxed.owl	regulation of voltage-gated potassium channel activity					This term was obsoleted at the TermGenie Gatekeeper stage.		sl	2013-05-21T15:12:06Z		True			biological_process											owl:Class	
GO:1905104	biolink:NamedThing	obsolete response to ouabain	OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ouabain stimulus.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted at the TermGenie Gatekeeper stage.		sl	2016-04-04T19:08:07Z		True			biological_process											owl:Class	
GO:0072317	biolink:NamedThing	obsolete glucan endo-1,3-beta-D-glucosidase activity involved in ascospore release from ascus	OBSOLETE. Catalysis of the hydrolysis of 1,3-beta-D-glucosidic linkages in 1,3-beta-D-glucans that contributes to the release of ascospores from the ascus.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/15204				This term was obsoleted because it should be captured as a GO-CAM model.		mah	2010-10-25T05:46:13Z		True			molecular_function											owl:Class	
GO:0004234	biolink:NamedThing	obsolete macrophage elastase activity	OBSOLETE. Catalysis of the hydrolysis of soluble and insoluble elastin. Specific cleavages are also produced at Ala14-Leu15 and Tyr16-Leu17 in the B chain of insulin.	tmpzr1t_l9r_go_relaxed.owl	macrophage elastase activity|human macrophage metalloelastase (HME)|matrix metalloproteinase 12 activity|metalloesterase activity|MMP-12|metalloelastase activity				EC:3.4.24.65|MetaCyc:3.4.24.65-RXN	This term was made obsolete because it represents a gene product.	GO:0004222|GO:0004175				True			molecular_function											owl:Class	
GO:0052432	biolink:NamedThing	obsolete modulation by organism of symbiont apoptosis	OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of programmed cell death in the symbiont, where programmed cell death proceeds by apoptosis. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	modulation by organism of symbiont apoptosis|modulation by organism of symbiont apoptotic programmed cell death					This term was made obsolete because it does not represent a real biological process.					True			biological_process											owl:Class	
GO:0009296	biolink:NamedThing	obsolete flagellum assembly	OBSOLETE. The assembly of a flagellum. In bacteria, this is a whiplike motility appendage present on the surface of some species; in eukaryotes, flagella are threadlike protoplasmic extensions used to propel flagellates and sperm. Flagella are composed of flagellin and have the same basic structure as cilia but are longer in proportion to the cell and present in much smaller numbers.	tmpzr1t_l9r_go_relaxed.owl	flagellum assembly|flagella biogenesis|flagellum biogenesis|flagella assembly						GO:0060271|GO:0044780				True			biological_process											owl:Class	
GO:1903164	biolink:NamedThing	obsolete succinate transmembrane transporter activity involved in succinate import into cell	OBSOLETE. Any succinate transmembrane transporter activity that is involved in succinate import into cell.	tmpzr1t_l9r_go_relaxed.owl	dicarboxylate (succinate/fumarate/malate) antiporter activity involved in succinate import into cell|succinate transmembrane transporter activity involved in succinate import into cell					This term was obsoleted at the TermGenie Gatekeeper stage.		dos	2014-07-09T11:56:55Z		True			molecular_function											owl:Class	
GO:0030616	biolink:NamedThing	obsolete transforming growth factor beta receptor, common-partner cytoplasmic mediator activity	OBSOLETE. A TGF-beta cytoplasmic mediator that forms a complex with a phosphorylated pathway-specific mediator. The heterocomplex translocates to the nucleus to regulate transcription.	tmpzr1t_l9r_go_relaxed.owl	common mediator SMAD protein|TGF-beta receptor, common-partner cytoplasmic mediator activity|common partner SMAD protein|TGFbeta receptor, common-partner cytoplasmic mediator activity|common-partner SMAD protein|common-mediator SMAD protein|co-SMAD protein	https://github.com/geneontology/go-ontology/issues/16202				This term was obsoleted because it is redundant with other terms.	GO:0000981|GO:0003712				True			molecular_function											owl:Class	
GO:0061813	biolink:NamedThing	obsolete ARID domain binding	OBSOLETE. Binding to a ARID domain. The AT-rich interaction domain (ARID) is an ~100-amino acid DNA-binding module found in a large number of eukaryotic transcription factors.	tmpzr1t_l9r_go_relaxed.owl								dph	2016-11-11T13:57:55Z		True			molecular_function											owl:Class	
GO:0005906	biolink:NamedThing	obsolete clathrin adaptor	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	clathrin adaptor|adaptin			GO:0030119		This term was made obsolete because it was positioned incorrectly, so the replacement term has a definition different from what this term appeared to mean.					True			cellular_component											owl:Class	
GO:1900460	biolink:NamedThing	obsolete negative regulation of invasive growth in response to glucose limitation by negative regulation of transcription from RNA polymerase II promoter	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of invasive growth in response to glucose limitation by stopping, preventing, or reducing the frequency, rate or extent of transcription from an RNA polymerase II promoter.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of colony morphology by negative regulation of transcription from RNA polymerase II promoter					This term was obsoleted because it represents a GO-CAM model.		dgf	2012-05-01T06:09:17Z		True			biological_process											owl:Class	
GO:0008717	biolink:NamedThing	obsolete D-alanyl-D-alanine endopeptidase activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	penicillin-binding protein 8|D-alanyl-D-alanine endopeptidase activity|penicillin-binding protein 7			GO:0004175		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:1905877	biolink:NamedThing	obsolete invadopodium assembly	OBSOLETE. The aggregation, arrangement and bonding together of a set of components to form an invadopodium.	tmpzr1t_l9r_go_relaxed.owl	invadopodium formation					This term was made obsolete because an invadopodium is an abnormal structure found in cancerous or transformed cells that is out of scope of GO.		sl	2017-01-27T20:44:07Z		True			biological_process											owl:Class	
GO:0052257	biolink:NamedThing	obsolete pathogen-associated molecular pattern dependent induction by organism of innate immune response of other organism involved in symbiotic interaction	OBSOLETE. Any process that involves recognition of a pathogen-associated molecular pattern, and by which an organism activates, maintains or increases the frequency, rate or extent of the innate immune response of a second organism, where the two organisms are in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	MAMP-dependent induction of innate immunity of other organism|general elicitor dependent induction of innate immunity of other organism|PAMP dependent induction of innate immunity of other organism|MAMP dependent induction of innate immunity of other organism|pathogen-associated molecular pattern dependent induction by organism of innate immunity of other organism involved in symbiotic interaction|PAMP-dependent induction of innate immunity of other organism|pathogen-associated molecular pattern dependent induction by organism of innate immunity of other organism during symbiotic interaction|general elicitor-dependent induction of innate immunity of other organism					This term was obsoleted because it has been misused.	GO:0052034|GO:0002221|GO:0002752				True			biological_process											owl:Class	
GO:0006815	biolink:NamedThing	obsolete sodium/potassium transport	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	sodium/potassium transport					This term was made obsolete because it is a composite term that represents two individual processes.	GO:0006814|GO:0006813				True			biological_process											owl:Class	
GO:0004625	biolink:NamedThing	obsolete calcium-dependent secreted phospholipase A2 activity	OBSOLETE. Catalysis of the reaction: phosphatidylcholine + H2O = 1-acylglycerophosphocholine + a fatty acid anion.	tmpzr1t_l9r_go_relaxed.owl	calcium-dependent secreted phospholipase A2 activity					This term was made obsolete because it represents component and function information.	GO:0047498|GO:0005576				True			molecular_function											owl:Class	
GO:0039566	biolink:NamedThing	obsolete suppression by virus of host STAT1 activity by tyrosine dephosphorylation of STAT1	OBSOLETE. Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host STAT1 (signal transducer and activator of transcription-1) activity by the removal of phosphoric residues from STAT1-O-phospho-tyrosine to form STAT1-tyrosine. For example, the viral phosphatase VH1 dephosphorylates STAT1 to reverse STAT1 activation.	tmpzr1t_l9r_go_relaxed.owl	suppression by virus of host STAT1 activity by peptidyl-tyrosine dephosphorylation of STAT1|viral tyrosine phosphatase activity involved in suppression of host STAT1					The reason for obsoleting this term is that it is too specific. The exact molecular roles of the individual proteins should be captured separately.		bf	2012-03-12T04:08:32Z		True			biological_process											owl:Class	
GO:0007357	biolink:NamedThing	obsolete positive regulation of central gap gene transcription	OBSOLETE. The activation of genes encoding transcription factors in the central region of an insect embryo by a combination of maternal regulatory signals and interactions among themselves; exemplified by the activation of expression of the Drosophila Kruppel gene by the hunchback and bicoid gene products.	tmpzr1t_l9r_go_relaxed.owl	upregulation of central gap gene transcription|up-regulation of central gap gene transcription|activation of central gap gene transcription|up regulation of central gap gene transcription|activation of central gap gene|stimulation of central gap gene transcription					This term was obsoleted because it represents a GO-CAM model.					True			biological_process											owl:Class	
GO:1990885	biolink:NamedThing	obsolete protein serine/threonine kinase binding	OBSOLETE. Binding to a protein serine/threonine kinase.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted at the TermGenie Gatekeeper stage.		sl	2015-10-28T20:40:57Z		True			molecular_function											owl:Class	
GO:0018065	biolink:NamedThing	obsolete protein-cofactor linkage	OBSOLETE. The covalent attachment of a cofactor to a protein.	tmpzr1t_l9r_go_relaxed.owl						1. Making inferences in GO about compounds based on the cofactor role curated by ChEBI creates relationships that are not always true which violates ontological principles for GO; therefore we will cease making these inferences. 2. It is not meaningful to group protein modification processes that are not all chemically related by the fact that they may be used as a cofactor.					True			biological_process											owl:Class	
GO:0010702	biolink:NamedThing	obsolete regulation of histolysis	OBSOLETE. Any process that modulates the rate, frequency or extent of the breakdown of tissues; usually, if not always, accompanied by cell death.	tmpzr1t_l9r_go_relaxed.owl						This term was made obsolete because it refers to a phenotype. When death of a cell or tissue is a result of a true biological process, this should be captured using 'programmed cell death' or one of its descendants.	GO:0008219|GO:0012501				True			biological_process											owl:Class	
GO:0019514	biolink:NamedThing	obsolete lactose hydrolysis	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	lactose hydrolysis					This term was made obsolete because hydrolysis is a reaction.	GO:0004565				True			biological_process											owl:Class	
GO:0005180	biolink:NamedThing	obsolete peptide hormone	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	peptide hormone					This term was made obsolete because it describes a type of hormone rather than a molecular function.	GO:0005179				True			molecular_function											owl:Class	
GO:0007123	biolink:NamedThing	obsolete bud scar accumulation	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	bud scar accumulation					This term was made obsolete because it is a phenotype rather than a biological process.	GO:0000282				True			biological_process											owl:Class	
GO:0000263	biolink:NamedThing	obsolete heterotrimeric G-protein GTPase, alpha-subunit	OBSOLETE. Subunit of a heterotrimeric G-protein GTPase that contains the guanine nucleotide binding site and possesses GTPase activity.	tmpzr1t_l9r_go_relaxed.owl	heterotrimeric G-protein GTPase, alpha-subunit					This term was made obsolete because it does not represent a molecular function.	GO:0003924|GO:0005834				True			molecular_function											owl:Class	
GO:0004295	biolink:NamedThing	obsolete trypsin activity	OBSOLETE. Catalysis of the preferential cleavage of Arg-Xaa, Lys-Xaa.	tmpzr1t_l9r_go_relaxed.owl	trypure|cocoonase activity|beta-trypsin activity|pseudotrypsin|tryptar|sperm receptor hydrolase activity|tripcellim|alpha-trypsin activity|trypsin activity|parenzymol|parenzyme			GO:0004252		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0001683	biolink:NamedThing	obsolete axonemal dynein heavy chain	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	axonemal dynein heavy chain			GO:0005858		This term was made obsolete because it represents a single gene product and not a complex.					True			cellular_component											owl:Class	
GO:0009634	biolink:NamedThing	obsolete heavy metal sensitivity/resistance	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	heavy metal sensitivity/resistance					This term was made obsolete because 'sensitivity/resistance' implies a phenotype rather than a biological process.	GO:0010038				True			biological_process											owl:Class	
GO:0016512	biolink:NamedThing	obsolete endothelin-converting enzyme 1 activity	OBSOLETE. Catalysis of the formation of endothelin 1 by cleavage of the Trp21-Val22 bond in the precursor.	tmpzr1t_l9r_go_relaxed.owl	ECE-1 activity|endothelin-converting enzyme 1 activity			GO:0004222		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:1902574	biolink:NamedThing	obsolete negative regulation of leucine import by regulation of transcription from RNA polymerase II promoter	OBSOLETE. A regulation of transcription from RNA polymerase II promoter that results in negative regulation of leucine import.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it represents a GO-CAM model.		al	2013-12-11T09:43:23Z		True			biological_process											owl:Class	
GO:0016171	biolink:NamedThing	obsolete cell surface antigen	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	cell surface antigen					This term was made obsolete because it represents a gene product, and because describing something as an 'antigen' means that an organism can produce antibodies to it, which says nothing about the gene product activity.					True			molecular_function											owl:Class	
GO:0052192	biolink:NamedThing	obsolete movement in environment of other organism involved in symbiotic interaction	OBSOLETE. The directed movement of an organism or motile cell on, within or near a second organism, where the two organisms are in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	locomotion in environment of other organism during symbiotic interaction|movement in environment of other organism during symbiotic interaction					This term was obsoleted because it represented both a process and a location.					True			biological_process											owl:Class	
GO:1903065	biolink:NamedThing	obsolete protein localization to cell tip involved in positive regulation of establishment of cell polarity regulating cell shape	OBSOLETE. Any protein localization to cell tip that is involved in positive regulation of establishment of cell polarity regulating cell shape.	tmpzr1t_l9r_go_relaxed.owl	protein localisation to cell tip involved in positive regulation of establishment of cell polarity regulating cell shape|protein localization to cell tip involved in positive regulation of establishment of cell polarity regulating cell shape					This term was obsoleted at the TermGenie Gatekeeper stage.		vw	2014-05-28T15:29:27Z		True			biological_process											owl:Class	
GO:0098663	biolink:NamedThing	obsolete transmembrane transporter activity involved in import into cell	OBSOLETE. Any transmembrane transporter activity that is involved in importing some substance into a cell.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/14322				The reason for obsoletion is that this terms partly represents the process "import into cell".					True			molecular_function											owl:Class	
GO:0071615	biolink:NamedThing	obsolete oxidative deethylation	OBSOLETE. The process of removing one or more ethyl groups from a molecule, involving the oxidation (i.e. electron loss) of one or more atoms in the substrate.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/20250				This term was obsoleted because it represents a molecular function.		mah	2010-02-05T06:11:41Z		True			biological_process											owl:Class	
GO:0048228	biolink:NamedThing	obsolete actin cortical patch distribution	OBSOLETE. Any process that establishes the spatial arrangement of actin cortical patches. An actin cortical patch is a discrete actin-containing structure found at the plasma membrane in fungal cells.	tmpzr1t_l9r_go_relaxed.owl	actin cortical patch distribution					This term was made obsolete because its definition is very similar to that of its parent term, actin cortical patch localization (GO:0051666), but somewhat unclear, and not similar enough to merge the terms.					True			biological_process											owl:Class	
GO:0008462	biolink:NamedThing	obsolete endopeptidase Clp activity	OBSOLETE. Catalysis of the hydrolysis of proteins to small peptides in the presence of ATP and magnesium. Alpha-casein is the usual test substrate. In the absence of ATP, only oligopeptides shorter than five residues are cleaved, for example, succinyl-Leu-Tyr-NHMec which is cleaved at the Tyr-NHMec bond, and Leu-Tyr-Leu-Tyr-Trp which is cleaved at the second Leu-Typ bond (cleavage of the Tyr-Leu and Tyr-Trp bonds also occurs).	tmpzr1t_l9r_go_relaxed.owl	caseinolytic protease activity|endopeptidase Ti activity|ClpP|Clp protease|endopeptidase Clp activity|ATP-dependent Clp protease|protease Ti activity			GO:0004252		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0047063	biolink:NamedThing	obsolete L-ascorbate-cytochrome-b5 reductase activity	OBSOLETE. Catalysis of the reaction: ferricytochrome B5 + ascorbate = ferrocytochrome B5 + monodehydroascorbate.	tmpzr1t_l9r_go_relaxed.owl	ascorbate-cytochrome b5 reductase activity|L-ascorbate:ferricytochrome-b5 oxidoreductase activity				MetaCyc:1.10.2.1-RXN|RHEA:18677|EC:1.10.2.1	This term was obsoleted because the EC and RHEA it represented was obsoleted.					True			molecular_function											owl:Class	
GO:0008181	biolink:NamedThing	obsolete tumor suppressor	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	tumor suppressor					This term was made obsolete because it does not represent a true biological function, rather a pathology that occurs when a particular gene product is inactivated in some way.	GO:0051726				True			molecular_function											owl:Class	
GO:0071430	biolink:NamedThing	obsolete pre-miRNA-containing ribonucleoprotein complex export from nucleus	OBSOLETE. The directed movement of a ribonucleoprotein complex that contains pre-microRNA from the nucleus to the cytoplasm.	tmpzr1t_l9r_go_relaxed.owl	pre-microRNA-containing ribonucleoprotein complex nucleus export|pre-microRNA-containing ribonucleoprotein complex transport from nucleus to cytoplasm|pre-microRNA-containing ribonucleoprotein complex export from cell nucleus|pre-microRNA-containing RNP export from nucleus|pre-microRNA-containing ribonucleoprotein complex export from nucleus	https://github.com/geneontology/go-ontology/issues/22246				This term has been obsoleted because it represents the transport of a carrier bound to its substrate.		mah	2009-12-16T10:26:16Z		True			biological_process											owl:Class	
GO:1900374	biolink:NamedThing	obsolete positive regulation of mating type switching by regulation of transcription from RNA polymerase II promoter	OBSOLETE. A regulation of transcription from RNA polymerase II promoter that results in positive regulation of mating type switching.	tmpzr1t_l9r_go_relaxed.owl	up-regulation of mating type switching by regulation of transcription from RNA polymerase II promoter|up regulation of mating type switching by regulation of transcription from RNA polymerase II promoter|activation of mating type switching by regulation of transcription from RNA polymerase II promoter|stimulation of mating type switching by regulation of transcription from RNA polymerase II promoter|upregulation of mating type switching by regulation of transcription from RNA polymerase II promoter					This term was obsoleted because it represents a GO-CAM model.		krc	2012-04-17T12:39:56Z		True			biological_process											owl:Class	
GO:0052446	biolink:NamedThing	obsolete modulation by organism of defense-related symbiont cell wall thickening	OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of symbiont processes resulting in the thickening of its cell walls, occurring as part of the defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	modulation by organism of defense-related symbiont cell wall thickening|modulation by organism of symbiont defensive cell wall thickening					This term was made obsolete because it does not represent a real biological process.					True			biological_process											owl:Class	
GO:0005395	biolink:NamedThing	obsolete eye pigment precursor transporter activity	OBSOLETE. Catalysis of the reaction: ATP + H2O + eye pigment precursor(in) = ADP + phosphate + eye pigment precursor(out).	tmpzr1t_l9r_go_relaxed.owl						This term has been obsoleted because eye pigment precursors are nucleotides and amino acids, and there are terms to annotate these functions.					True			molecular_function											owl:Class	
GO:0034624	biolink:NamedThing	obsolete DNA recombinase assembly involved in gene conversion at mating-type locus	OBSOLETE. The aggregation, arrangement and bonding together of strand exchange proteins (recombinases) into higher order oligomers on single-stranded DNA, involved in the conversion of the mating-type locus from one allele to another.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/19999				This term was obsoleted because it represents a GO-CAM model.					True			biological_process											owl:Class	
GO:0016326	biolink:NamedThing	obsolete kinesin motor activity	OBSOLETE. The hydrolysis of ATP (and GTP) that drives the microtubular motor along microtubules.	tmpzr1t_l9r_go_relaxed.owl	kinesin motor activity			GO:0003777		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0035951	biolink:NamedThing	obsolete positive regulation of oligopeptide transport by positive regulation of transcription from RNA polymerase II promoter	OBSOLETE. Any process that activates or increases the frequency, rate or extent of oligopeptide transport by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of oligopeptide transport by stimulation of transcription from RNA polymerase II promoter|positive regulation of oligopeptide transport by upregulation of transcription from RNA polymerase II promoter|positive regulation of oligopeptide transport by up regulation of transcription from RNA polymerase II promoter|positive regulation of oligopeptide transport by activation of transcription from RNA polymerase II promoter|positive regulation of oligopeptide transport by positive regulation of transcription from Pol II promoter|positive regulation of oligopeptide transport by up-regulation of transcription from RNA polymerase II promoter					This term was obsoleted because it represents a GO-CAM model.		bf			True			biological_process											owl:Class	
GO:0045305	biolink:NamedThing	obsolete regulator of establishment of competence for transformation activity	OBSOLETE. Functions to either promote or inhibit the establishment of competence for transformation.	tmpzr1t_l9r_go_relaxed.owl	regulator of establishment of competence for transformation activity			GO:0045304		This term was made obsolete because it does not represent a true function.					True			molecular_function											owl:Class	
GO:0045099	biolink:NamedThing	obsolete vimentin	OBSOLETE. A type of intermediate filament.	tmpzr1t_l9r_go_relaxed.owl	vimentin			GO:0045098		This term was made obsolete because it represents a gene product.					True			cellular_component											owl:Class	
GO:0016271	biolink:NamedThing	obsolete tissue death	OBSOLETE. A permanent cessation of all vital functions of a tissue.	tmpzr1t_l9r_go_relaxed.owl						This term was made obsolete because it refers to a phenotype. When death of a cell or tissue is a result of a true biological process, this should be captured using 'programmed cell death' or one of its descendants.	GO:0012501|GO:0008219				True			biological_process											owl:Class	
GO:0000195	biolink:NamedThing	obsolete nuclear translocation of MAPK (pseudohyphal growth)	OBSOLETE. Movement of a MAP kinase to the nucleus in the context of regulating pseudohyphal or invasive growth.	tmpzr1t_l9r_go_relaxed.owl	nuclear translocation of MAPK (pseudohyphal growth)					This term was made obsolete because it is a gene product specific term.					True			biological_process											owl:Class	
GO:0052191	biolink:NamedThing	obsolete positive regulation by symbiont of host phagocytosis	OBSOLETE. Any process in which an organism activates, maintains or increases the frequency, rate or extent of phagocytosis, the engulfing by phagocytes of external particulate material, in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	stimulation by symbiont of host phagocytosis|up-regulation by symbiont of host phagocytosis|upregulation by symbiont of host phagocytosis|activation by symbiont of host phagocytosis|up regulation by symbiont of host phagocytosis	https://github.com/geneontology/go-ontology/issues/18562				This term was obsoleted because there is no evidence that this process exists.					True			biological_process											owl:Class	
GO:0008436	biolink:NamedThing	obsolete heterogeneous nuclear ribonucleoprotein	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	heterogeneous nuclear ribonucleoprotein|hnRNP			GO:1990904		This term was made obsolete because it describes a cellular component rather than a molecular function.					True			molecular_function											owl:Class	
GO:0033199	biolink:NamedThing	obsolete inositol heptakisphosphate 4-kinase or 6-kinase activity	OBSOLETE. Catalysis of the reaction: ATP + 5-diphospho-1D-myo-inositol (1,2,3,4,6)pentakisphosphate = 4,5-bisdiphosphoinositol-1D-myoinositol (1,2,3,6)tetrakisphosphate, and ATP + 5-diphospho-1D-myo-inositol (1,2,3,4,6)pentakisphosphate = 5,6-bisdiphosphoinositol-1D-myoinositol (1,2,3,4)tetrakisphosphate.	tmpzr1t_l9r_go_relaxed.owl	inositol heptakisphosphate 4-kinase or 6-kinase activity					This term was made obsolete because it represents two reactions, and should be two separate terms.	GO:0000834|GO:0000833				True			molecular_function											owl:Class	
GO:0008225	biolink:NamedThing	obsolete Gram-negative antibacterial peptide activity	OBSOLETE. Inhibits the growth of, or directly kills, Gram-negative bacterial cells.	tmpzr1t_l9r_go_relaxed.owl	Gram-negative antibacterial peptide activity					This term was made obsolete because it describes involvement in a process and not a function.	GO:0050829				True			molecular_function											owl:Class	
GO:0004213	biolink:NamedThing	obsolete cathepsin B activity	OBSOLETE. Catalysis of the hydrolysis of peptide bonds with a broad specificity. Preferentially cleaves the terminal bond of -Arg-Arg-Xaa motifs in small molecule substrates (thus differing from cathepsin L). In addition to being an endopeptidase, shows peptidyl-dipeptidase activity, liberating C-terminal dipeptides.	tmpzr1t_l9r_go_relaxed.owl	cathepsin B1 activity|cathepsin B activity|cathepsin II			GO:0004197		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0051822	biolink:NamedThing	obsolete dissemination or transmission of organism from other organism by vector involved in symbiotic interaction	OBSOLETE. The movement of an organism from a second organism to another place in the environment by means of a vector, where the two organisms are in a symbiotic interaction. The first organism may also move to a different organism, and the vector organism is often an insect or an animal.	tmpzr1t_l9r_go_relaxed.owl	dissemination or transmission of organism from other organism by vector during symbiotic interaction					This term was obsoleted because it did not represent a specific process, but represented the life cycle of a symbiont.					True			biological_process											owl:Class	
GO:2000577	biolink:NamedThing	obsolete regulation of microtubule motor activity, minus-end-directed	OBSOLETE. Any process that modulates the frequency, rate or extent of ATP-dependent microtubule motor activity, minus-end-directed.	tmpzr1t_l9r_go_relaxed.owl	regulation of minus-end-directed microtubule motor activity|regulation of kinesin ATP phosphohydrolase (minus-end-directed)|regulation of ATP-dependent microtubule motor activity, minus-end-directed|regulation of minus-end-directed kinesin ATPase activity	https://github.com/geneontology/go-ontology/issues/21626				This term was obsoleted because it represents a molecular function.	GO:0140659	bf	2011-04-05T08:37:52Z		True			biological_process											owl:Class	
GO:0043064	biolink:NamedThing	obsolete flagellum organization	OBSOLETE. A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a flagellum, a long thin projection from a cell, used in movement.	tmpzr1t_l9r_go_relaxed.owl	flagellum organization|flagellum organisation|flagellum organization and biogenesis					This term was made obsolete because microtubule-based flagellum (GO:0009434) and motile cilium (GO:0031514), as referenced by this term, were determined to be equivalent and merged. When a merge for this term was considered, it was noticed that both eukaryotic and prokaryotic proteins are annotated to it because its meaning had been ambiguous so obsoletion was considered safest.	GO:0044781|GO:0044782				True			biological_process											owl:Class	
GO:0044701	biolink:NamedThing	obsolete response to stimulus by single organism	OBSOLETE. A response to a stimulus that involves only one organism.	tmpzr1t_l9r_go_relaxed.owl	response to stimulus by single organism					This term was made obsolete because we decided that all responses are single-organism.		jl	2012-09-19T15:40:57Z		True			biological_process											owl:Class	
GO:0005323	biolink:NamedThing	obsolete very-low-density lipoprotein	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	VLDL|very-low-density lipoprotein			GO:0005319		This term was made obsolete because it does not represent a molecular function.					True			molecular_function											owl:Class	
GO:0044043	biolink:NamedThing	obsolete multi-organism glucan metabolic process	OBSOLETE. The chemical reactions and pathways involving glucans, polysaccharides consisting only of glucose residues, involving more than one organism.	tmpzr1t_l9r_go_relaxed.owl	multi-organism glucan metabolism					This term was obsoleted because there is no evidence it exists.					True			biological_process											owl:Class	
GO:0001011	biolink:NamedThing	obsolete transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting	OBSOLETE. Binding to a specific DNA sequence and recruiting RNA polymerase to the DNA in order to form the preinitiation complex (PIC).	tmpzr1t_l9r_go_relaxed.owl	sequence-specific DNA binding RNA polymerase recruiting transcription factor activity					This term was obsoleted because it was not clearly defined and usage has been inconsistent.	GO:0140223	krc	2010-08-18T06:49:16Z		True			molecular_function											owl:Class	
GO:0015482	biolink:NamedThing	obsolete voltage-gated anion channel porin activity	OBSOLETE. This term was not defined before being made obsolete.	tmpzr1t_l9r_go_relaxed.owl	voltage-gated anion channel porin activity|voltage-dependent anion channel porin activity					This term was made obsolete because it wrongly combines voltage-gated anion channel activity and porin activity.					True			molecular_function											owl:Class	
GO:0075171	biolink:NamedThing	obsolete regulation of MAP kinase-mediated signal transduction in response to host	OBSOLETE. Any process in which the symbiont organism modulates the frequency, rate or extent of its MAP kinase-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	regulation of symbiont MAP kinase-mediated signal transduction in response to host					This term was obsoleted because there is no evidence that this process exists.					True			biological_process											owl:Class	
GO:1901639	biolink:NamedThing	obsolete XDP catabolic process	OBSOLETE. The chemical reactions and pathways resulting in the breakdown of XDP.	tmpzr1t_l9r_go_relaxed.owl	XDP catabolism|XDP degradation|XDP breakdown	https://github.com/geneontology/go-ontology/issues/20954				This term was obsoleted because there is no evidence that this reaction exist in vivo.		tb	2012-11-15T22:56:26Z		True			biological_process											owl:Class	
GO:0015981	biolink:NamedThing	obsolete passive proton transport, down the electrochemical gradient	OBSOLETE. The passive movement of protons from areas of high proton concentration and electrical potential to areas where concentration and electrical potential are low.	tmpzr1t_l9r_go_relaxed.owl	passive proton transport, down the electrochemical gradient					This term was made obsolete because it represents a passive process which occurs without the aid of gene products.	GO:1902600				True			biological_process											owl:Class	
GO:0010670	biolink:NamedThing	obsolete positive regulation of oxygen and reactive oxygen species metabolic process	OBSOLETE. Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving dioxygen (O2), or any of the reactive oxygen species, e.g. superoxide anions (O2-), hydrogen peroxide (H2O2), and hydroxyl radicals (-OH).	tmpzr1t_l9r_go_relaxed.owl	positive regulation of oxygen and reactive oxygen species metabolic process					This term was made obsolete because, as part of the GO/ChEBI alignment effort, curators determined that oxygen and reactive oxygen species should not be grouped together.	GO:2000379|GO:2000376				True			biological_process											owl:Class	
GO:0046234	biolink:NamedThing	obsolete fluorene biosynthetic process	OBSOLETE. The chemical reactions and pathways resulting in the formation of fluorene, a tricyclic polycyclic aromatic hydrocarbon containing a five-membered ring. It is a major component of fossil fuels and their derivatives and is also a by-product of coal-conversion and energy-related industries. It is commonly found in vehicle exhaust emissions, crude oils, motor oils, coal and oil combustion products, waste incineration, and industrial effluents.	tmpzr1t_l9r_go_relaxed.owl	fluorene anabolism|fluorene synthesis|fluorene biosynthetic process|fluorene formation|fluorene biosynthesis					This term was made obsolete because fluorene is not synthesized by living organisms and GO does not cover non-biological processes.					True			biological_process											owl:Class	
GO:0051370	biolink:NamedThing	obsolete ZASP binding	OBSOLETE. Binding to Z-band alternatively spliced PDZ motif protein (ZASP). ZASP is a Z-band protein specifically expressed in heart and skeletal muscle. This protein contains N-terminal PDZ domain and C-terminal LIM domain.	tmpzr1t_l9r_go_relaxed.owl	Z-band alternatively spliced PDZ-motif protein binding|ZASP binding			GO:0008092		This term was made obsolete because it represents binding to an individual protein.					True			molecular_function											owl:Class	
RO:0002296	biolink:NamedThing	results in development of		tmpzr1t_l9r_go_relaxed.owl					RO:0002296									external									results_in_development_of			
GO:0001305	biolink:NamedThing	obsolete progressive alteration of chromatin involved in chronological cell aging	OBSOLETE. A process that results in changes in chromatin structure contributing to chronological cell aging, occurring in non-dividing cells.	tmpzr1t_l9r_go_relaxed.owl	progressive alteration of chromatin during chronological cell aging|progressive alteration of chromatin during chronological cell ageing	https://github.com/geneontology/go-ontology/issues/18632				This term was obsoleted because it represent an assay - how long the cell lives -, not a true biological process.	GO:0090398|GO:0044838				True			biological_process											owl:Class	
GO:0004702	biolink:NamedThing	obsolete signal transducer, downstream of receptor, with serine/threonine kinase activity	OBSOLETE. Conveys a signal from an upstream receptor or intracellular signal transducer by catalysis of the reaction: ATP protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.	tmpzr1t_l9r_go_relaxed.owl	receptor signalling protein serine/threonine kinase activity|receptor signaling protein serine/threonine kinase activity	https://github.com/geneontology/go-ontology/issues/14232			EC:2.7.11.-	This term was obsoleted because it was not clearly defined.					True			molecular_function											owl:Class	
GO:0000020	biolink:NamedThing	obsolete negative regulation of recombination within rDNA repeats	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of genetic recombination within the DNA of the genes coding for ribosomal RNA.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of recombination within rDNA repeats					This term was made obsolete because it describes a substrate-specific process.	GO:0045950				True			biological_process											owl:Class	
GO:0017175	biolink:NamedThing	obsolete IMP-GMP specific 5'-nucleotidase activity	OBSOLETE. Catalysis of the conversion of 5'-ribonucleotides to ribonucleosides and phosphate, with specificity for IMP or GMP 5'-ribonucleotides and H2O as a nucleophile.	tmpzr1t_l9r_go_relaxed.owl	IMP-GMP specific 5'-nucleotidase activity					This term was made obsolete because it represents a gene product with two different activities.	GO:0050484				True			molecular_function											owl:Class	
GO:0016218	biolink:NamedThing	obsolete polyketide synthase activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	polyketide synthase activity			GO:0030639		This term was made obsolete because the activity it describes does not exist, and the gene product with the name 'polyketide synthase' has multiple functional domains, so using the name to describe a single function would be misleading.	GO:0034081				True			molecular_function											owl:Class	
GO:0015984	biolink:NamedThing	obsolete uniport	OBSOLETE. The process of noncoupled solute translocation or facilitated diffusion.	tmpzr1t_l9r_go_relaxed.owl	uniport			GO:0015292		This term was made obsolete because it represents a molecular function rather than a biological process.					True			biological_process											owl:Class	
GO:0052237	biolink:NamedThing	obsolete aerotaxis in other organism involved in symbiotic interaction	OBSOLETE. The movement of a motile cell or organism in response to environmental oxygen within a second organism, where the two organisms are in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	aerotaxis in other organism during symbiotic interaction|aerotaxis within other organism during symbiotic interaction	https://github.com/geneontology/go-ontology/issues/18819				This term was obsoleted because it represents both a process and a location.					True			biological_process											owl:Class	
GO:0015305	biolink:NamedThing	obsolete lactose, galactose:proton symporter activity	OBSOLETE. Catalysis of the reaction: (lactose or galactose)(out) + H+(out) = (lactose or galactose)(in) + H+(in).	tmpzr1t_l9r_go_relaxed.owl	lactose, galactose:hydrogen symporter activity|lactose,galactose:proton symporter activity|lactose, galactose:proton symporter activity					This term was made obsolete because it represents two molecular functions.	GO:0015528|GO:0015517				True			molecular_function											owl:Class	
GO:0006981	biolink:NamedThing	obsolete activation of SoxR protein	OBSOLETE. The conversion of the SoxR transcription factor to its active (oxidized) form.	tmpzr1t_l9r_go_relaxed.owl						This term was made obsolete because it was too specific with respect to a single gene product.					True			biological_process											owl:Class	
GO:0052362	biolink:NamedThing	obsolete catabolism by host of symbiont protein	OBSOLETE. The chemical reactions and pathways performed by an organism resulting in the breakdown of protein macromolecules within the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/21469				This term was obsoleted because it represents a molecular function.					True			biological_process											owl:Class	
GO:0001132	biolink:NamedThing	obsolete RNA polymerase II transcription factor activity, TBP-class protein binding	OBSOLETE. Binding to a member of the class of TATA-binding proteins (TBP), including any of the TBP-related factors (TRFs), in order to modulate transcription. The transcription factor may or may not also interact selectively with DNA as well.	tmpzr1t_l9r_go_relaxed.owl	TRF protein binding RNA polymerase II transcription factor activity|TATA-binding protein binding RNA polymerase II transcription factor activity|TBP-class protein binding RNA polymerase II transcription factor activity	https://github.com/geneontology/go-ontology/issues/16053				The reason for obsoletion is that this concept is partly covered by other concepts in the ontology and usage has been inconsistent.		krc	2011-01-20T04:15:44Z		True			molecular_function											owl:Class	
GO:1901487	biolink:NamedThing	obsolete negative regulation of SREBP signaling pathway by positive regulation of transcription factor catabolic process in response to increased oxygen levels	OBSOLETE. Positive regulation of transcription factor catabolism in response to increased oxygen levels, which results in negative regulation of the SREBP signaling pathway.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of SREBP-mediated signaling pathway in response to increased oxygen levels by positive regulation of transcription factor catabolic process|negative regulation of SREBP signaling pathway by positive regulation of SREBP degradation, in response to elevated oxygen|negative regulation of SREBP signaling by acceleration of SREBP degradation, in response to increased oxygen levels|negative regulation of SREBP-mediated signaling pathway in presence of oxygen by positive regulation of transcription factor catabolic process|negative regulation of SREBP signaling by positive regulation of transcription factor catabolism in response to increased oxygen levels	https://github.com/geneontology/go-ontology/issues/14544				The reason for obsoletion is that this is better captured in a GO-CAM model.		bf	2012-10-09T08:23:33Z		True			biological_process											owl:Class	
GO:0075338	biolink:NamedThing	obsolete modulation of growth or development of symbiont during interaction with host	OBSOLETE. Any process that modulates the frequency, rate or extent of the increase in size or mass of an organism, or the progression of an organism from an initial condition to a later condition, occurring in, on or near the exterior of its host organism.	tmpzr1t_l9r_go_relaxed.owl	modulation of growth or development of symbiont during interaction with host					This term was made obsolete because it contained a conjunction (or).	GO:0044145				True			biological_process											owl:Class	
GO:0052462	biolink:NamedThing	obsolete modulation by host of symbiont phagocytosis	OBSOLETE. Any process in which an organism modulates the frequency, rate or extent of phagocytosis, the engulfing by phagocytes of external particulate material, in the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because there is no evidence that this process exists.					True			biological_process											owl:Class	
GO:1900472	biolink:NamedThing	obsolete positive regulation of phosphatidylcholine biosynthetic process by positive regulation of transcription from RNA polymerase II promoter	OBSOLETE. Any process that activates or increases the frequency, rate or extent of phosphatidylcholine biosynthetic process by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of phosphatidylcholine anabolism by positive regulation of transcription from RNA polymerase II promoter|positive regulation of phosphatidylcholine biosynthesis by positive regulation of transcription from RNA polymerase II promoter|positive regulation of phosphatidylcholine synthesis by positive regulation of transcription from RNA polymerase II promoter|positive regulation of phosphatidylcholine formation by positive regulation of transcription from RNA polymerase II promoter					This term was obsoleted because it represents a GO-CAM model.		dgf	2012-05-01T08:13:36Z		True			biological_process											owl:Class	
GO:0052238	biolink:NamedThing	obsolete aerotaxis on or near other organism involved in symbiotic interaction	OBSOLETE. The movement of a motile cell or organism in response to environmental oxygen on or near a second organism, where the two organisms are in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	aerotaxis on or near other organism during symbiotic interaction	https://github.com/geneontology/go-ontology/issues/18819				This term was obsoleted because it represents both a process and a location.					True			biological_process											owl:Class	
GO:0015641	biolink:NamedThing	obsolete lipoprotein toxin	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	lipoprotein toxin					This term was made obsolete because it represents a gene product.	GO:0090729				True			molecular_function											owl:Class	
GO:0098766	biolink:NamedThing	obsolete meiosis I M phase	OBSOLETE. M phase during meiosis I.	tmpzr1t_l9r_go_relaxed.owl						Obsoleted because added in error.	GO:0098762				True			biological_process											owl:Class	
GO:0052465	biolink:NamedThing	obsolete modulation by organism of defense-related symbiont reactive oxygen species production	OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of the production of reactive oxygen species as part of the defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	modulation by organism of defense-related symbiont reactive oxygen species production|modulation by organism of defense-related symbiont oxidative burst|modulation by organism of defense-related symbiont reactive oxygen intermediate production|modulation by organism of defense-related symbiont active oxygen species production|modulation by organism of defense-related symbiont AOS production|modulation by organism of defense-related symbiont metabolic burst|modulation by organism of defense-related symbiont reactive oxidative species production|modulation by organism of defense-related symbiont ROI production|modulation by organism of defense-related symbiont respiratory burst|modulation by organism of defense-related symbiont ROS production					This term was made obsolete because it does not represent a real biological process.					True			biological_process											owl:Class	
GO:0016626	biolink:NamedThing	obsolete oxidoreductase activity, acting on the aldehyde or oxo group of donors, other acceptors	OBSOLETE. Catalysis of an oxidation-reduction (redox) reaction in which an aldehyde or ketone (oxo) group acts as a hydrogen or electron donor and reduces an acceptor other than NAD, NADP, oxygen, an iron-sulfur protein, disulphide or a cytochrome.	tmpzr1t_l9r_go_relaxed.owl	oxidoreductase activity, acting on the aldehyde or oxo group of donors, other acceptors					This term was made obsolete because it was an unnecessary grouping term.	GO:0016903				True			molecular_function											owl:Class	
GO:0090401	biolink:NamedThing	obsolete viral-induced premature senescence	OBSOLETE. A cellular senescence process associated with the dismantling of a cell as a response to viral infection.	tmpzr1t_l9r_go_relaxed.owl						The reason for obsoletion is was not clearly defined. There is nothing in the literature that mentions this process; there are papers that mention viral proteins overcoming premature senescence, for example, PMID:22326283.		tb	2011-01-05T02:37:57Z		True			biological_process											owl:Class	
GO:0061416	biolink:NamedThing	obsolete regulation of transcription from RNA polymerase II promoter in response to salt stress	OBSOLETE. Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is under salt stress. The stress is usually an increase or decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/12739				This term was obsoleted because it represents a GO-CAM model.	GO:0006357|GO:0071472	dph	2012-01-23T12:56:36Z		True			biological_process											owl:Class	
GO:0006845	biolink:NamedThing	obsolete mitochondrial aspartate/glutamate transport	OBSOLETE. The directed movement of aspartate and glutamate into, out of or within a mitochondrion.	tmpzr1t_l9r_go_relaxed.owl	mitochondrial aspartate/glutamate transport					This term was made obsolete because it represents a function rather than a process.	GO:0015810|GO:0015813|GO:0006839				True			biological_process											owl:Class	
GO:0005156	biolink:NamedThing	obsolete epidermal growth factor receptor inhibiting ligand activity	OBSOLETE. This term was not defined before being made obsolete.	tmpzr1t_l9r_go_relaxed.owl	EGFR inhibiting ligand activity|epidermal growth factor receptor inhibiting ligand activity|EGF receptor inhibiting ligand activity			GO:0005154		This term was made obsolete because it represents both a biological process and a molecular function.	GO:0007175|GO:0030293				True			molecular_function											owl:Class	
GO:0072361	biolink:NamedThing	obsolete regulation of glycolytic process by regulation of transcription from RNA polymerase II promoter	OBSOLETE. Any process that modulates the frequency, rate or extent of glycolysis by modulating the frequency, rate or extent of transcription from an RNA polymerase II promoter.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it represents a GO-CAM model.		mah	2010-11-16T02:57:18Z		True			biological_process											owl:Class	
GO:0042971	biolink:NamedThing	obsolete lactone transmembrane transporter activity	OBSOLETE. Enables the transfer of lactone from one side of a membrane to the other. A lactone is a cyclic ester of a hydroxy carboxylic acid, containing a 1-oxacycloalkan-2-one structure, or an analogue having unsaturation or heteroatoms replacing one or more carbon atoms of the ring.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because there is no evidence for a specific lactone transporter.					True			molecular_function											owl:Class	
GO:0007003	biolink:NamedThing	obsolete telomere binding	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	telomere binding			GO:0042162		This term was made obsolete because it represents a molecular function and not a biological process.					True			biological_process											owl:Class	
GO:0100042	biolink:NamedThing	obsolete negative regulation of pseudohyphal growth by transcription from RNA polymerase II promoter	OBSOLETE. Any transcription from RNA polymerase II promoter process that negatively regulates pseudohyphal growth.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it represents a GO-CAM model.		cjm	2015-04-02T04:13:19Z		True			biological_process											owl:Class	
GO:1990436	biolink:NamedThing	obsolete MAPK cascade involved in oxidative stress signaling pathway	OBSOLETE. A series of molecular signals in which a MAP kinase cascade activated by oxidative stress relays one or more of the signals, MAP kinase cascades involve at least three protein kinase activities and culminate in the phosphorylation and activation of a MAP kinase. Just FYI in pombe the osmotic stress and oxidative stress MAPK cascade involve many of the same proteins, but the pathways are slightly different, therefore Im req this term.	tmpzr1t_l9r_go_relaxed.owl	MAPK cascade involved in oxidative stress signaling pathway					This term was obsoleted at the TermGenie Gatekeeper stage.		al	2014-07-31T10:10:38Z		True			biological_process											owl:Class	
GO:0021867	biolink:NamedThing	obsolete neuron-producing asymmetric radial glial cell division in forebrain	OBSOLETE. The unequal mitotic division of a radial glial cell in the forebrain that gives rise to a radial glial cell and a post-mitotic neuronal progenitor.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it represents a GO-CAM model.					True			biological_process											owl:Class	
GO:1990979	biolink:NamedThing	obsolete copper ion transport across blood-brain barrier	OBSOLETE. The directed movement of copper ions passing through the blood-brain barrier.	tmpzr1t_l9r_go_relaxed.owl	copper ion transport across BBB					This term was obsoleted at the TermGenie Gatekeeper stage.		sl	2016-08-17T21:09:08Z		True			biological_process											owl:Class	
GO:0085004	biolink:NamedThing	obsolete interaction with host via secreted substance released from haustorium	OBSOLETE. An interaction with the host organism mediated by a substance released by the other (symbiont) organism via the haustorium, a projection from a cell or tissue that penetrates the host's cell wall. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl						This term was deprecated because it conflated the process in which a gene product is involved with the secretion system by which it reaches its target.		jl	2010-02-10T02:58:39Z		True			biological_process											owl:Class	
GO:0018988	biolink:NamedThing	obsolete molting cycle, protein-based cuticle	OBSOLETE. The periodic shedding of part or all of a protein-based cuticle, which is then replaced by a new protein-based cuticle. A cuticle is the outer layer of an animal which acts to prevent water loss.	tmpzr1t_l9r_go_relaxed.owl	protein-based cuticle molting cycle					This term was made obsolete because 'protein-based cuticle' is an unnecessary grouping term.	GO:0018996|GO:0007591				True			biological_process											owl:Class	
GO:0061506	biolink:NamedThing	obsolete DNA topoisomerase type II (ATP-independent) activity	OBSOLETE. Catalysis of a DNA topological transformation by transiently cleaving a pair of complementary DNA strands to form a gate through which a second double-stranded DNA segment is passed, after which the severed strands in the first DNA segment are rejoined; product release is not coupled to ATP binding and hydrolysis; changes the linking number in multiples of 2.	tmpzr1t_l9r_go_relaxed.owl						This term was made obsolete because there is no evidence that this function exists. There are no known type II topoisomerase enzymes that are ATP-independent; as far as we know, ALL type II topoisomerase enzymes utilize hydrolysis of ATP.		dph	2013-01-23T10:41:58Z		True			molecular_function											owl:Class	
GO:0015339	biolink:NamedThing	obsolete cobalt, zinc uptake permease activity	OBSOLETE. Catalysis of the reaction: (Zn2+ or Co2+)(out) = (Zn2+ or Co2+)(in). The activity is driven by proton motive force, possibly by proton symport.	tmpzr1t_l9r_go_relaxed.owl	cobalt, zinc uptake permease activity					This term was made obsolete because it represents more than one molecular function.	GO:0015087|GO:0005385				True			molecular_function											owl:Class	
GO:1905250	biolink:NamedThing	obsolete positive regulation of memory	OBSOLETE. Any process that activates or increases the frequency, rate or extent of memory.	tmpzr1t_l9r_go_relaxed.owl	enhancement of memory					This term was obsoleted at the TermGenie Gatekeeper stage.		ha	2016-06-09T13:54:53Z		True			biological_process											owl:Class	
GO:0017074	biolink:NamedThing	obsolete procollagen N-endopeptidase activity	OBSOLETE. Catalysis of the cleavage of the N-propeptide of collagen chain alpha-1(I) at Pro-Gln and of alpha-1(II) and alpha-2(I) chains at Ala-Gln.	tmpzr1t_l9r_go_relaxed.owl	type I/II procollagen N-proteinase activity|procollagen N-proteinase activity|procollagen N-terminal proteinase activity|type III procollagen|aminoterminal procollagen peptidase activity|aminoprocollagen peptidase activity|procollagen N-endopeptidase activity|procollagen aminoterminal protease activity|procollagen N-terminal peptidase activity|procollagen aminopeptidase activity			GO:0004222		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0007559	biolink:NamedThing	obsolete histolysis	OBSOLETE. The breakdown of tissues; usually, if not always, accompanied by cell death, followed by the complete dissolution of dead tissue.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Histolysis	This term was made obsolete because it refers to a phenotype. When death of a cell or tissue is a result of a true biological process, this should be captured using 'programmed cell death' or one of its descendants.	GO:0008219|GO:0012501				True			biological_process											owl:Class	
GO:1990857	biolink:NamedThing	obsolete APC-Fzr1/Mfr1 complex	OBSOLETE. An anaphase promoting complex bound to an activator in the Fzr1 (human)/Mfr1 (pombe) family.	tmpzr1t_l9r_go_relaxed.owl						This term was made obsolete because it is too fine-grained for GO.	GO:0005680	al	2015-09-22T13:29:11Z		True			cellular_component											owl:Class	
GO:1990493	biolink:NamedThing	obsolete cyclin H-CDK7 complex	OBSOLETE. A protein complex consisting of cyclin H and cyclin-dependent kinase 7 (CDK7). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner.	tmpzr1t_l9r_go_relaxed.owl	cyclin H-CDK7 complex					This term was made obsolete because it was added in error.		al	2014-09-24T10:08:44Z		True			cellular_component											owl:Class	
GO:0085000	biolink:NamedThing	obsolete modification by symbiont of host morphology or physiology via protein secreted by type V secretion system	OBSOLETE. The process in which an organism effects a change in the structure or function of its host organism, mediated by a substance secreted by a type V secretion system in the organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it conflated the process in which a gene product is involved with the secretion system by which it reaches its target.		jl	2010-07-09T03:08:54Z		True			biological_process											owl:Class	
GO:0015062	biolink:NamedThing	obsolete violet-sensitive opsin	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	violet-sensitive opsin					This term was made obsolete because it refers to a class of proteins.	GO:0016021|GO:0007603|GO:0009881|GO:0016918|GO:0046876|GO:0009588				True			molecular_function											owl:Class	
GO:0006162	biolink:NamedThing	obsolete purine/pyrimidine nucleoside diphosphate reduction	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	purine/pyrimidine nucleoside diphosphate reduction					This term was made obsolete because it represents a molecular function rather than a biological process.	GO:0004748				True			biological_process											owl:Class	
GO:0019846	biolink:NamedThing	obsolete enterotoxin activity	OBSOLETE. Acts as to cause injury to the intestinal mucosa of other living organisms.	tmpzr1t_l9r_go_relaxed.owl	enterotoxin activity					This term was made obsolete because it represents a class of gene products.	GO:0090729				True			molecular_function											owl:Class	
GO:0046297	biolink:NamedThing	obsolete 2,4-dichlorobenzoate biosynthetic process	OBSOLETE. The chemical reactions and pathways resulting in the formation of 2,4-dichlorobenzoate, a chlorinated aromatic compound which is a key intermediate in the aerobic degradation of polychlorinated biphenyls (PCBs).	tmpzr1t_l9r_go_relaxed.owl	2,4-dichlorobenzoate anabolism|2,4-dichlorobenzoate synthesis|2,4-dichlorobenzoate biosynthetic process|2,4-dichlorobenzoate formation|2,4-dichlorobenzoate biosynthesis			GO:0018898		This term was made obsolete because 2,4-dichlorobenzoate is not synthesized by living organisms, and GO does not cover non-biological processes.					True			biological_process											owl:Class	
GO:0006247	biolink:NamedThing	obsolete TTP reduction	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	TTP reduction					This term was made obsolete because it represents a molecular function rather than a biological process.	GO:0051064				True			biological_process											owl:Class	
GO:1900412	biolink:NamedThing	obsolete regulation of histone methylation by regulation of transcription from RNA polymerase II promoter	OBSOLETE. A regulation of transcription from RNA polymerase II promoter that results in regulation of histone methylation.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it describes a process that does not exist.		mah	2012-04-20T03:35:36Z		True			biological_process											owl:Class	
GO:0080080	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0075345	biolink:NamedThing	obsolete modification by symbiont of host protein	OBSOLETE. The covalent alteration by an organism of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications) of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/21469				This term was obsoleted because it represents a molecular function.					True			biological_process											owl:Class	
GO:0030802	biolink:NamedThing	obsolete regulation of cyclic nucleotide biosynthetic process	OBSOLETE. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cyclic nucleotides.	tmpzr1t_l9r_go_relaxed.owl	regulation of cyclic nucleotide biosynthesis|regulation of cyclic nucleotide formation|regulation of cyclic nucleotide anabolism|regulation of cyclic nucleotide synthesis					The reason for obsoletion is that this term represents the regulation of a signaling pathway, not regulation of metabolism.					True			biological_process											owl:Class	
RO:0002336	biolink:NamedThing	positively regulated by		tmpzr1t_l9r_go_relaxed.owl					RO:0002336									external									positively_regulated_by			
GO:0052097	biolink:NamedThing	obsolete interspecies quorum sensing	OBSOLETE. The process in which a community of single-celled organisms of different species monitors population density by detecting the concentration of small diffusible signal molecules.	tmpzr1t_l9r_go_relaxed.owl						The reason for obsoletion is that this term was an unnecessary grouping term.					True			biological_process											owl:Class	
GO:0005804	biolink:NamedThing	obsolete secretory vesicle membrane	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	secretory vesicle membrane					This term was made obsolete because its parent was made obsolete.	GO:0030667|GO:0030658				True			cellular_component											owl:Class	
GO:0019794	biolink:NamedThing	obsolete nonprotein amino acid metabolic process	OBSOLETE. The chemical reactions and pathways involving any amino acid not found, or rarely found, in peptide linkage in proteins.	tmpzr1t_l9r_go_relaxed.owl	nonprotein amino acid metabolism|nonprotein amino acid metabolic process			GO:0006520		This term was made obsolete because it was a grouping term that was poorly defined and did not provide a particularly meaningful grouping, since even for those amino acids commonly found in proteins, not all molecules necessarily end up incorporated into proteins. The term also violated the principle of positivity.					True			biological_process											owl:Class	
GO:0071437	biolink:NamedThing	obsolete invadopodium	OBSOLETE. A cell projection that emerges from the ECM-facing surface of a cell, is enriched in actin and associated cytoskeletal proteins, and displays localized proteolytic activity toward the substrate.	tmpzr1t_l9r_go_relaxed.owl						This term was made obsolete because an invadopodium is an abnormal structure found in cancerous or transformed cells that is out of scope of GO.		mah	2009-12-16T02:19:58Z		True			cellular_component											owl:Class	
GO:0051193	biolink:NamedThing	obsolete regulation of cofactor metabolic process	OBSOLETE. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a cofactor.	tmpzr1t_l9r_go_relaxed.owl	regulation of cofactor metabolism					1. Making inferences in GO about compounds based on the cofactor role curated by ChEBI creates relationships that are not always true which violates ontological principles for GO; therefore we will cease making these inferences. 2. It is not meaningful to group metabolic processes that are not all chemically related by the fact that they may be used as a cofactor.					True			biological_process											owl:Class	
GO:0015461	biolink:NamedThing	obsolete endosomal oligosaccharide transporter	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	endosomal oligosaccharide transporter					This term was made obsolete because it contains both component and function information.	GO:0015157|GO:0005768				True			molecular_function											owl:Class	
GO:1904163	biolink:NamedThing	obsolete regulation of triglyceride homeostasis	OBSOLETE. Any process that modulates the frequency, rate or extent of triglyceride homeostasis.	tmpzr1t_l9r_go_relaxed.owl	regulation of triacylglycerol homeostasis					This term was obsoleted at the TermGenie Gatekeeper stage.		rph	2015-04-22T11:04:43Z		True			biological_process											owl:Class	
GO:1905929	biolink:NamedThing	obsolete positive regulation of invadopodium disassembly	OBSOLETE. Any process that activates or increases the frequency, rate or extent of invadopodium disassembly.	tmpzr1t_l9r_go_relaxed.owl	upregulation of invadopodium disassembly|up-regulation of invadopodium disassembly|activation of invadopodium disassembly|up regulation of invadopodium disassembly					This term was made obsolete because an invadopodium is an abnormal structure found in cancerous or transformed cells that is out of scope of GO.		sl	2017-02-08T21:39:14Z		True			biological_process											owl:Class	
GO:0008975	biolink:NamedThing	obsolete pitrilysin activity	OBSOLETE. Catalysis of the preferential cleavage of Tyr16-Leu17 and Phe25-Tyr26 bonds of oxidized insulin B chain. Also acts on other substrates of Molecular weight less than 7 kDa such as insulin and glucagon.	tmpzr1t_l9r_go_relaxed.owl	PTR|Escherichia coli protease III|protease Pi activity|proteinase Pi|protease III activity|Escherichia coli metalloproteinase Pi|pitrilysin activity			GO:0004222		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0044035	biolink:NamedThing	obsolete multi-organism catabolic process	OBSOLETE. A catabolic process - chemical reactions and pathways resulting in the breakdown of substances - which involves more than one organism.	tmpzr1t_l9r_go_relaxed.owl	multi-organismal catabolic process|multi-organismal catabolism|multi-organism catabolism	https://github.com/geneontology/go-ontology/issues/19769				This term was obsoleted because there is no evidence that this process exists.					True			biological_process											owl:Class	
GO:0098811	biolink:NamedThing	obsolete transcriptional repressor activity, RNA polymerase II activating transcription factor binding	OBSOLETE. Binding to an RNA polymerase II activating transcription factor and also with the RNA polymerase II basal transcription machinery in order to stop, prevent, or reduce the frequency, rate or extent of transcription.	tmpzr1t_l9r_go_relaxed.owl	RNA polymerase II activating transcription factor binding transcription repressor activity|RNA polymerase II transcription repressor activity|RNA polymerase II activating transcription factor binding transcription factor activity involved in negative regulation of transcription	https://github.com/geneontology/go-ontology/issues/16053				The reason for obsoletion is that this concept is partly covered by other concepts in the ontology and usage has been inconsistent.	GO:0001227	krc	2011-08-25T02:12:30Z		True			molecular_function											owl:Class	
GO:0016644	biolink:NamedThing	obsolete oxidoreductase activity, acting on the CH-NH2 group of donors, other acceptors	OBSOLETE. Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH2 group acts as a hydrogen or electron donor and reduces an acceptor other than a cytochrome, disulfide, an iron-sulfur protein, NAD, NADP or oxygen.	tmpzr1t_l9r_go_relaxed.owl	oxidoreductase activity, acting on the CH-NH2 group of donors, other acceptors					This term was made obsolete because it was an unnecessary grouping term.	GO:0016638				True			molecular_function											owl:Class	
GO:0008530	biolink:NamedThing	obsolete exogenous peptide receptor activity	OBSOLETE. Combining with an extracellular peptide to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	exogenous peptide receptor activity					This term was made obsolete because it contains both component and function information.	GO:0005576|GO:0001653				True			molecular_function											owl:Class	
GO:0001506	biolink:NamedThing	obsolete neurotransmitter biosynthetic process and storage	OBSOLETE. The chemical reactions and pathways resulting in the formation of neurotransmitters and the storage of the synthesized molecules.	tmpzr1t_l9r_go_relaxed.owl	neurotransmitter formation and storage|neurotransmitter biosynthetic process and storage|neurotransmitter synthesis and storage|neurotransmitter anabolism and storage					This term was made obsolete because it is an amalgamation of its two children.	GO:0042136|GO:0042137				True			biological_process											owl:Class	
GO:0044044	biolink:NamedThing	obsolete interaction with host via substance in symbiont surface	OBSOLETE. An interaction with the host organism mediated by a substance on the surface of the other (symbiont) organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl						The reason for obsoletion is that these terms conflate a process and the mechanism of secretion of the compound mediating the process.					True			biological_process											owl:Class	
GO:0046195	biolink:NamedThing	obsolete 4-nitrophenol biosynthetic process	OBSOLETE. The chemical reactions and pathways resulting in the formation of 4-nitrophenol, a nitroaromatic compound which is used in the production of dyes, leather treatment agents, fungicides and as an intermediate in the production of the insecticide parathion.	tmpzr1t_l9r_go_relaxed.owl	4-nitrophenol anabolism|4-nitrophenol formation|4-nitrophenol biosynthesis|4-nitrophenol synthesis|4-nitrophenol biosynthetic process			GO:0018960		This term was made obsolete because 4-nitrophenol is not synthesized by living organisms, and GO does not cover non-biological processes.					True			biological_process											owl:Class	
GO:0075155	biolink:NamedThing	obsolete negative regulation of transmembrane receptor-mediated signal transduction in response to host	OBSOLETE. Any process in which the symbiont organism stops, prevents, or reduces the frequency, rate or extent of its symbiont transmembrane receptor-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of symbiont transmembrane receptor-mediated signal transduction in response to host					This term was obsoleted because there is no evidence that this process exists.					True			biological_process											owl:Class	
GO:0043498	biolink:NamedThing	obsolete cell surface binding	OBSOLETE. Binding to a component on the surface of a cell.	tmpzr1t_l9r_go_relaxed.owl	cell surface binding					This term was made obsolete because it is ambiguous and causing confusion, and is an unnecessary grouping term.	GO:0007155|GO:0046812|GO:0009986|GO:0005102|GO:0003823				True			molecular_function											owl:Class	
GO:0003718	biolink:NamedThing	obsolete RNA polymerase III transcription termination factor activity	OBSOLETE. Any activity that brings about termination of transcription by RNA polymerase III.	tmpzr1t_l9r_go_relaxed.owl	Pol III transcription termination factor activity|RNA polymerase III transcription termination factor activity					This term was obsoleted because it is essentially identical to a Process term (specifically the Biological Process term which has been selected as a term to consider for reannotation), i.e. it is defined only in terms of the process it acts in and it does NOT convey any information about the molecular nature of the function or whether the function is based on binding DNA, on interacting with other proteins, or some other mechanism. To transfer all annotations without review, the BP term indicated is considered to be equivalent and thus the only appropriate destination for all annotations. To reannotate to a MF term, you will probably need to revisit the original literature or other primary data because this "MF" term was not defined in terms of mechanism of action and there are multiple possibilities in the revised MF structure. In reannotation, please also consider descendent terms of the suggested MF terms as a more specific term may be more appropriate than the MF terms indicated. Please be aware that you may wish to request a new term if the mechanism of action of this gene product is not yet represented or if you are annotating for an RNAP different than one for which there is a specific suggested term. Also note that if there is no information about how the gene product acts, it may be appropriate to annotate to the root term for molecular_function.	GO:0006386				True			molecular_function											owl:Class	
GO:0016771	biolink:NamedThing	obsolete transferase activity, transferring other nitrogenous groups	OBSOLETE. Catalysis of the transfer of a nitrogenous group, other than amino, amidino or oxime, from one compound (donor) to another (acceptor).	tmpzr1t_l9r_go_relaxed.owl	transferase activity, transferring other nitrogenous groups					This term was made obsolete because it was an unnecessary grouping term.	GO:0016769				True			molecular_function											owl:Class	
GO:0005551	biolink:NamedThing	obsolete ubiquitin	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl						This term was made obsolete because it represents a gene product.	GO:0031386|GO:0016567				True			molecular_function											owl:Class	
GO:0000061	biolink:NamedThing	obsolete protein import into nucleus, substrate release	OBSOLETE. A protein complex disassembly process that contributes to protein import into the nucleus, and that results in the dissociation of the cargo protein and the carrier (such as an importin alpha/beta heterodimer) from each other and from the nuclear pore complex.	tmpzr1t_l9r_go_relaxed.owl	protein transport from cytoplasm to nucleus, substrate release|protein substrate release during protein-nucleus import|protein-nucleus import, substrate release|protein substrate release during protein transport from cytoplasm to nucleus|protein substrate release during protein import into nucleus|protein import into cell nucleus, substrate release					This term has been obsoleted because it represents a substep of the parent (GO:0006606 protein import into nucleus), has been incorrectly used.					True			biological_process											owl:Class	
GO:0036425	biolink:NamedThing	obsolete D-phosphoserine phosphatase activity	OBSOLETE. Catalysis of the reaction: O-phospho-D-serine + H2O = L-serine + phosphate, on a free amino acid.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/21638				This term was obsoleted because there is no evidence that this function exisis. This reaction corresponds to RHEA:24873 and KEGG_REACTION:R02853.	GO:0036424	bf	2013-09-16T13:02:43Z		True			molecular_function											owl:Class	
GO:0005734	biolink:NamedThing	obsolete box C + D snoRNP protein	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	box C + D snoRNP protein					This term was made obsolete because it represents a gene product.					True			cellular_component											owl:Class	
GO:1900406	biolink:NamedThing	obsolete regulation of conjugation with cellular fusion by regulation of transcription from RNA polymerase II promoter	OBSOLETE. A regulation of transcription from RNA polymerase II promoter that results in regulation of conjugation with cellular fusion.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it represents a GO-CAM model.		mah	2012-04-20T02:46:24Z		True			biological_process											owl:Class	
GO:0061887	biolink:NamedThing	obsolete reproduction of symbiont in host	OBSOLETE. The production of new individuals that contain some portion of genetic material inherited from one or more parent organisms, occurring within the cells or tissues of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it represents a process and a component.		dph	2017-06-01T18:07:47Z		True			biological_process											owl:Class	
GO:0030405	biolink:NamedThing	obsolete matrix metalloproteinase 19 activity	OBSOLETE. Was not defined before being made obsolete.	tmpzr1t_l9r_go_relaxed.owl	MMP-19|matrix metalloproteinase 19 activity			GO:0004222		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0007581	biolink:NamedThing	obsolete age-dependent yeast cell size increase	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	age-dependent yeast cell size increase					This term was made obsolete because it does not describe a biological process.	GO:0007571				True			biological_process											owl:Class	
GO:0097285	biolink:NamedThing	obsolete cell-type specific apoptotic process	OBSOLETE. Any apoptotic process in a specific cell type.	tmpzr1t_l9r_go_relaxed.owl	cell-type specific apoptosis					This term was made obsolete because it was an unnecessary grouping term.	GO:0006915	pr	2012-03-29T04:00:25Z		True			biological_process											owl:Class	
GO:0034883	biolink:NamedThing	obsolete isonicotinate reductase activity	OBSOLETE. Catalysis of the reaction: isonicotinate + 2 H+ + 2 e- = 1,4-dihydroisonicotinate.	tmpzr1t_l9r_go_relaxed.owl	isonicotinate reductase activity					This term was made obsolete because it was derived from a UM-BBD enzyme entry that has been deleted, and no other information can be found to suggest that it is a naturally occurring activity.	GO:0016627				True			molecular_function											owl:Class	
GO:0008132	biolink:NamedThing	obsolete pancreatic elastase activity	OBSOLETE. Catalysis of the hydrolysis of proteins, including elastin.	tmpzr1t_l9r_go_relaxed.owl	pancreatic elastase activity			GO:0004252		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0085007	biolink:NamedThing	obsolete interaction with host via secreted substance released from rhoptry	OBSOLETE. An interaction with the host organism mediated by a substance released by the other (symbiont) organism via the rhoptry, a large, club-shaped secretory organelle that forms part of the apical complex of an apicomplexan parasite. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl						This term was deprecated because it conflated the process in which a gene product is involved with the secreaton system by which it reaches its target.		jl	2010-02-10T03:02:08Z		True			biological_process											owl:Class	
GO:1990652	biolink:NamedThing	obsolete positive regulation of pyrimidine-containing compound salvage by positive regulation of transcription from RNA polymerase II promoter	OBSOLETE. A positive regulation of transcription from RNA polymerase II promoter that results in positive regulation of pyrimidine-containing compound salvage.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of pyrimidine-containing compound salvage by positive regulation of transcription from RNA polymerase II promoter					This term was obsoleted at the TermGenie Gatekeeper stage.		al	2015-02-23T11:25:51Z		True			biological_process											owl:Class	
GO:0019026	biolink:NamedThing	obsolete negative sense viral genome	OBSOLETE. A single stranded RNA genome with the opposite nucleotide polarity as mRNA.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it does not represent a GO cellular component.					True			cellular_component											owl:Class	
GO:0045557	biolink:NamedThing	obsolete TRAIL receptor biosynthetic process	OBSOLETE. The chemical reactions and pathways resulting in the formation of the TRAIL (TNF-related apoptosis inducing ligand) receptor.	tmpzr1t_l9r_go_relaxed.owl	TRAIL receptor anabolism|TRAIL receptor formation|TRAIL receptor synthesis|TRAIL receptor biosynthesis	https://github.com/geneontology/go-ontology/issues/19900				The reason for obsoletion is that those represent specific gene products, and genes annotated to those terms should be annotated to 'regulation of gene expression' or 'regulation of transcription' or some signaling term.					True			biological_process											owl:Class	
GO:0045568	biolink:NamedThing	obsolete positive regulation of TRAIL receptor 2 biosynthetic process	OBSOLETE. Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of TRAIL (TNF-related apoptosis inducing ligand) receptor 2.	tmpzr1t_l9r_go_relaxed.owl	up regulation of TRAIL receptor 2 biosynthetic process|positive regulation of TRAIL receptor 2 formation|positive regulation of TRAIL receptor 2 anabolism|positive regulation of TRAIL receptor 2 biosynthesis|activation of TRAIL receptor 2 biosynthetic process|positive regulation of TRAIL receptor 2 synthesis|up-regulation of TRAIL receptor 2 biosynthetic process|stimulation of TRAIL receptor 2 biosynthetic process|upregulation of TRAIL receptor 2 biosynthetic process	https://github.com/geneontology/go-ontology/issues/19900				The reason for obsoletion is that those represent specific gene products, and genes annotated to those terms should be annotated to 'regulation of gene expression' or 'regulation of transcription' or some signaling term.					True			biological_process											owl:Class	
GO:0030459	biolink:NamedThing	obsolete inactivation of MAPK (mating sensu Fungi)	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	inactivation of MAPK (mating sensu Fungi)			GO:0000750		This term was made obsolete because it is a gene product specific term.					True			biological_process											owl:Class	
GO:0035897	biolink:NamedThing	obsolete proteolysis in other organism	OBSOLETE. The chemical reactions and pathways performed by an organism resulting in the hydrolysis of proteins in another organism by cleavage of their peptide bonds.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/21469				This term was obsoleted because it represents a molecular function.		bf	2011-06-15T03:00:27Z		True			biological_process											owl:Class	
GO:0005837	biolink:NamedThing	obsolete 26S proteasome	OBSOLETE. A large multisubunit protease found in the cytosol that recognizes, unfolds, and digests protein substrates that have been marked for degradation by the attachment of a ubiquitin group. Individual subcomplexes of the complete 26S proteasome are involved in these different tasks: the ATP-dependent 19S caps are believed to unfold substrates and feed them to the actual protease, the 20S proteasome.	tmpzr1t_l9r_go_relaxed.owl	26S proteasome					This term was made obsolete because its definition was inaccurate.	GO:0000502				True			cellular_component											owl:Class	
GO:0000300	biolink:NamedThing	obsolete peripheral to membrane of membrane fraction	OBSOLETE. Peripheral to that fraction of cells, prepared by disruptive biochemical methods, that includes the plasma and other membranes; can be extracted from membrane fraction with high concentrations of salt or high pH.	tmpzr1t_l9r_go_relaxed.owl	peripheral to membrane of membrane fraction					This term was made obsolete because it refers to a cell fractionation experimental result and not a bona fide cellular component.	GO:0019898				True			cellular_component											owl:Class	
GO:0008549	biolink:NamedThing	obsolete dynamin GTPase activity	OBSOLETE. Catalysis of the reaction: GTP + H2O = GDP + phosphate. An enzyme that is involved in endocytosis and is instrumental in pinching off membrane vesicles.	tmpzr1t_l9r_go_relaxed.owl	dynamin GTPase activity|dynamine GTPase activity			GO:0003924		This term was made obsolete because it represents a gene product.	GO:0006897				True			molecular_function											owl:Class	
GO:0004443	biolink:NamedThing	obsolete inositol-1,4,-bisphosphate 4-phosphatase	OBSOLETE. Catalysis of the reaction: D-myo-inositol 3,4-bisphosphate + H2O = D-myo-inositol 3-monophosphate + phosphate.	tmpzr1t_l9r_go_relaxed.owl	inositol-1,4,-bisphosphate 4-phosphatase						GO:0016316				True			molecular_function											owl:Class	
GO:0009858	biolink:NamedThing	obsolete compatible pollen-pistil interaction	OBSOLETE. An interaction between a pollen grain and pistil that results in unimpeded growth of the pollen tube through the stigma and style.	tmpzr1t_l9r_go_relaxed.owl	compatible pollen-pistil interaction					This term was made obsolete because it represents a phenotype.					True			biological_process											owl:Class	
has_participant	biolink:NamedThing	has participant		tmpzr1t_l9r_go_relaxed.owl					RO:0000057									external									has_participant			
GO:0016946	biolink:NamedThing	obsolete cathepsin F activity	OBSOLETE. Catalysis of the hydrolysis of peptide bonds. Cleavage of substrates with Phe and Leu in P2.	tmpzr1t_l9r_go_relaxed.owl	cathepsin F activity			GO:0004197		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0016343	biolink:NamedThing	obsolete cytoskeletal anchoring activity	OBSOLETE. The direct or indirect linkage of cytoskeletal filaments to the plasma membrane.	tmpzr1t_l9r_go_relaxed.owl	cytoskeletal anchoring activity					This term was made obsolete because it represents a biological process.					True			molecular_function											owl:Class	
GO:0075191	biolink:NamedThing	obsolete autophagy of host cells on or near symbiont surface	OBSOLETE. The process in which the host cells digest parts of their own cytoplasm, occurring when the host is on or near its symbiont surface. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl						The reason for obsoletion is that this term did not represent any specific host/symbiont process.					True			biological_process											owl:Class	
GO:0005707	biolink:NamedThing	obsolete interphase chromosome	OBSOLETE. A chromosome found in the cell during interphase of the cell cycle. Chromosomes are usually decondensed during interphase and each long DNA molecule in a chromosome is divided into a large number of discrete domains that are folded differently.	tmpzr1t_l9r_go_relaxed.owl	interphase chromosome					This term was made obsolete because it is based on a temporal division of the cell cycle.	GO:0005694				True			cellular_component											owl:Class	
GO:0100039	biolink:NamedThing	obsolete regulation of pyrimidine nucleotide biosynthetic process by transcription from RNA polymerase II promoter	OBSOLETE. Any transcription from RNA polymerase II promoter process that regulates pyrimidine nucleotide biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it represents a GO-CAM model.		cjm	2015-04-02T04:13:19Z		True			biological_process											owl:Class	
GO:0006184	biolink:NamedThing	obsolete GTP catabolic process	OBSOLETE. The chemical reactions and pathways resulting in the breakdown of GTP, guanosine triphosphate.	tmpzr1t_l9r_go_relaxed.owl	GTP degradation|GTP hydrolysis|GTP breakdown|GTP catabolism					The reason for making this term obsolete is that it gets misused in cases where phosphates are simply being removed from a small molecule. We found no cases where these molecules genuinely underwent catabolism.	GO:0003924				True			biological_process											owl:Class	
GO:1904741	biolink:NamedThing	obsolete positive regulation of filamentous growth of a population of unicellular organisms in response to starvation by positive regulation of transcription from RNA polymerase II promoter	OBSOLETE. A positive regulation of transcription from RNA polymerase II promoter that results in positive regulation of filamentous growth of a population of unicellular organisms in response to starvation.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of filamentous growth of a population of unicellular organisms in response to starvation by activation of transcription from RNA polymerase II promoter|positive regulation of filamentous growth of a population of unicellular organisms in response to starvation by stimulation of transcription from RNA polymerase II promoter|positive regulation of filamentous growth of a population of unicellular organisms in response to starvation by up-regulation of global transcription from RNA polymerase II promoter|positive regulation of filamentous growth of a population of unicellular organisms in response to starvation by positive regulation of transcription from RNA polymerase II promoter, global|positive regulation of filamentous growth of a population of unicellular organisms in response to starvation by upregulation of transcription from RNA polymerase II promoter|positive regulation of filamentous growth of a population of unicellular organisms in response to starvation by activation of global transcription from RNA polymerase II promoter|positive regulation of filamentous growth of a population of unicellular organisms in response to starvation by positive regulation of gene-specific transcription from RNA polymerase II promoter|positive regulation of filamentous growth of a population of unicellular organisms in response to starvation by positive regulation of global transcription from Pol II promoter|positive regulation of filamentous growth of a population of unicellular organisms in response to starvation by up regulation of transcription from RNA polymerase II promoter|positive regulation of filamentous growth of a population of unicellular organisms in response to starvation by positive regulation of transcription from Pol II promoter|positive regulation of filamentous growth of a population of unicellular organisms in response to starvation by stimulation of global transcription from RNA polymerase II promoter|positive regulation of filamentous growth of a population of unicellular organisms in response to starvation by upregulation of global transcription from RNA polymerase II promoter|positive regulation of filamentous growth of a population of unicellular organisms in response to starvation by up regulation of global transcription from RNA polymerase II promoter|positive regulation of filamentous growth of a population of unicellular organisms in response to starvation by up-regulation of transcription from RNA polymerase II promoter					This term was obsoleted because it represents a GO-CAM model.		tb	2015-10-15T21:40:43Z		True			biological_process											owl:Class	
GO:0016865	biolink:NamedThing	obsolete intramolecular oxidoreductase activity, other intramolecular oxidoreductases	OBSOLETE. A grouping term for intramolecular oxidoreductases that cannot be more accurately categorized.	tmpzr1t_l9r_go_relaxed.owl	intramolecular oxidoreductase activity, other intramolecular oxidoreductases|intramolecular isomerase activity, other intramolecular oxidoreductases					This term was made obsolete because it was an unnecessary grouping term.	GO:0016860				True			molecular_function											owl:Class	
GO:0000456	biolink:NamedThing	obsolete dimethylation involved in SSU-rRNA maturation	OBSOLETE. Dimethylation of the N6 amino groups of two consecutive adenosine residues near the 3'-end of the SSU rRNA. This process has been conserved from bacteria to eukaryotes.	tmpzr1t_l9r_go_relaxed.owl						The reason for obsoletion is that this term can be captured as a GO-CAM model.					True			biological_process											owl:Class	
GO:0001404	biolink:NamedThing	obsolete invasive growth	OBSOLETE. Growth of a pathogenic organism that results in penetration into cells or tissues of the host organism. This often (but not necessarily) includes a filamentous growth form, and also can include secretion of proteases and lipases to break down host tissue.	tmpzr1t_l9r_go_relaxed.owl	invasive growth|tissue invasion					This term was made obsolete because more appropriate terms were created.	GO:0044409				True			biological_process											owl:Class	
GO:0061746	biolink:NamedThing	obsolete single-stranded DNA-dependent GTPase activity	OBSOLETE. Catalysis of the reaction: GTP + H2O = GDP + phosphate; this reaction requires the presence of single-stranded DNA, and it drives another reaction.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/19078				This term was obsoleted because there is no evidence that this reaction occurs under physiological conditions.		dph	2015-11-11T12:50:19Z		True			molecular_function											owl:Class	
GO:0007515	biolink:NamedThing	obsolete lymph gland development	OBSOLETE. The process whose specific outcome is the progression of the lymph gland over time, from its formation to the mature structure. The lymph gland is a small bean-shaped organ made up of a loose meshwork of reticular tissue in which are enmeshed large numbers of lymphocytes, macrophages and accessory cells. Lymph glands are located along the lymphatic system.	tmpzr1t_l9r_go_relaxed.owl	lymph gland development					This term was made obsolete because it was wrongly defined.	GO:0048535|GO:0048542				True			biological_process											owl:Class	
GO:0100025	biolink:NamedThing	obsolete negative regulation of cellular amino acid biosynthetic process by transcription from RNA polymerase II promoter	OBSOLETE. Any transcription from RNA polymerase II promoter process that negatively regulates cellular amino acid biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it represents a GO-CAM model.		cjm	2015-04-02T04:13:19Z		True			biological_process											owl:Class	
GO:0017149	biolink:NamedThing	obsolete protein biosynthetic process inhibitor activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	protein formation inhibitor activity|protein biosynthetic process inhibitor activity|protein anabolism inhibitor activity|protein synthesis inhibitor activity			GO:0017148		This term was made obsolete because it represents involvement in a biological process.					True			molecular_function											owl:Class	
GO:0052244	biolink:NamedThing	obsolete negative energy taxis in other organism involved in symbiotic interaction	OBSOLETE. The directed movement of a motile cell or organism within a second organism towards a lower level of a physical stimulus involved in energy generation, such as light, oxygen, and oxidizable substrates, where the two organisms are in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	negative energy taxis in other organism during symbiotic interaction|negative energy taxis within other organism during symbiotic interaction	https://github.com/geneontology/go-ontology/issues/18819				This term was obsoleted because it represents both a process and a location.					True			biological_process											owl:Class	
GO:0004263	biolink:NamedThing	obsolete chymotrypsin activity	OBSOLETE. Catalysis of the preferential cleavage of Tyr-Xaa > Trp-Xaa > Phe-Xaa > Leu-Xaa.	tmpzr1t_l9r_go_relaxed.owl	avazyme|chymotrypsin B activity|enzeon|chymotrypsin activity|alpha-chymotrypsin activity|chymotrypsin A activity|quimotrase activity|chymar|alpha-chymar|alpha-chymotrypsin A|chymotrypsins A and B|chymotest|quimar|alpha-chymar ophth			GO:0004252		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0051672	biolink:NamedThing	obsolete catabolism by organism of cell wall peptidoglycan in other organism	OBSOLETE. The chemical reactions and pathways resulting in the breakdown of the cell wall peptidoglycans of another organism.	tmpzr1t_l9r_go_relaxed.owl	cell wall catabolic process in other organism|cell wall peptidoglycan catabolic process in another organism|cell wall catabolism in other organism|catabolism of cell wall peptidoglycans of other organism|catabolic process of cell wall peptidoglycans of other organism	https://github.com/geneontology/go-ontology/issues/21469				This term was obsoleted because it represents a molecular function.					True			biological_process											owl:Class	
GO:1905547	biolink:NamedThing	obsolete regulation of subtelomeric heterochromatin assembly	OBSOLETE. Any process that modulates the frequency, rate or extent of subtelomeric heterochromatin assembly.	tmpzr1t_l9r_go_relaxed.owl	regulation of telomeric heterochromatin assembly|regulation of telomeric heterochromatin formation	https://github.com/geneontology/go-ontology/issues/19188|https://github.com/geneontology/go-ontology/issues/22027				This term was obsoleted because there is no evidence that chromatin silencing /heterochromatin assembly are directly regulated.		nc	2016-10-12T11:14:00Z		True			biological_process											owl:Class	
GO:0005678	biolink:NamedThing	obsolete chromatin assembly complex	OBSOLETE. Any protein complex that acts in the formation of nucleosomes or higher order chromatin structure.	tmpzr1t_l9r_go_relaxed.owl	nucleosome assembly complex|chromatin assembly complex					This term was made obsolete because its definition no longer reflects and cannot be modified to be consistent with the current state of knowledge.	GO:0031497				True			cellular_component											owl:Class	
GO:0018329	biolink:NamedThing	obsolete enzyme active site formation via N6-(phospho-5'-adenosine)-L-lysine	OBSOLETE. The transient adenylylation of lysine to form N6-(phospho-5'-adenosine)-L-lysine, found in the active site of DNA ligase and RNA ligase.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/15594			RESID:AA0227	This term was obsoleted because it represents a reaction intermediate, not a biological process, see PMID:4944632 and and PMID:3882425.	GO:0003910				True			biological_process											owl:Class	
GO:0042891	biolink:NamedThing	obsolete antibiotic transport	OBSOLETE. The directed movement of an antibiotic, a substance produced by or derived from certain fungi, bacteria, and other organisms, that can destroy or inhibit the growth of other microorganisms, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/17082				The reason for obsoletion is that this term has been inconsistently used. For export of an antibiotic by the organism that synthesizes it, consider 'GO:0140115 ; export across plasma membrane'. For export of an antibiotic by the target organism, consider 'GO:1990961 ; xenobiotic detoxification by transmembrane export across the plasma membrane'.					True			biological_process											owl:Class	
GO:1904946	biolink:NamedThing	obsolete cellular response to cobalt(II) acetate	OBSOLETE. Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cobalt(II) acetate stimulus.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted at the TermGenie Gatekeeper stage.		mr	2016-02-02T16:48:00Z		True			biological_process											owl:Class	
GO:0019719	biolink:NamedThing	obsolete smooth microsome	OBSOLETE. Vesicular particles formed from disrupted endoplasmic reticulum and plasma membranes without any adhering ribosomes.	tmpzr1t_l9r_go_relaxed.owl	smooth microsome					This term was made obsolete because it refers to a cell fractionation experimental result and not a bona fide cellular component.	GO:0005790				True			cellular_component											owl:Class	
GO:0052468	biolink:NamedThing	obsolete modulation by organism of salicylic acid levels in symbiont	OBSOLETE. The alteration by an organism of the levels of salicylic acid in the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	modulation by organism of salicylic acid levels in symbiont					This term was made obsolete because it does not represent a real biological process.					True			biological_process											owl:Class	
GO:0046908	biolink:NamedThing	obsolete negative regulation of crystal formation	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the spontaneous (nonenzymatic) formation of crystals in a solution, for example, calcium oxalate crystals in urine.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of crystal formation|negative regulation of mineralization			GO:0050801		This term was made obsolete because a more appropriate term was created.					True			biological_process											owl:Class	
GO:0003799	biolink:NamedThing	obsolete antifungal peptide activity	OBSOLETE. Inhibits the growth of, or directly kills, fungal cells.	tmpzr1t_l9r_go_relaxed.owl	antifungal peptide activity					This term was made obsolete because it describes involvement in a process and not a function.	GO:0050832				True			molecular_function											owl:Class	
GO:0033663	biolink:NamedThing	obsolete negative regulation by symbiont of host defense-related protein level	OBSOLETE. Any process in which the symbiont reduces of the levels of defense-related proteins in its host. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it is a readout, and annotations should be made to more informative terms.					True			biological_process											owl:Class	
GO:1990582	biolink:NamedThing	obsolete intracellular membrane-bounded organelle binding	OBSOLETE. The temporary binding of a protein or protein complex to the membrane of an intracellular membrane-bounded organelle.	tmpzr1t_l9r_go_relaxed.owl	intracellular membrane-enclosed organelle binding|intracellular membrane-bounded organelle binding					This term was obsoleted at the TermGenie Gatekeeper stage.		sl	2014-12-10T19:37:09Z		True			molecular_function											owl:Class	
GO:0008575	biolink:NamedThing	obsolete proteasome ATPase activity	OBSOLETE. Catalysis of the reaction: ATP + H2O = ADP + phosphate. The hydrolysis of ATP for channel gating and polypeptide unfolding before proteolysis in the proteasome. Six ATPase subunits are present in the regulatory particle (RP) of 26S proteasome.	tmpzr1t_l9r_go_relaxed.owl	proteasome ATPase activity					This term was made obsolete because it mentions a component term in the term text string.	GO:0016887				True			molecular_function											owl:Class	
GO:0009500	biolink:NamedThing	obsolete dicluster bacterial-type ferredoxin	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	dicluster bacterial-type ferredoxin			GO:0009055		This term was made obsolete because it does not represent a function.					True			molecular_function											owl:Class	
GO:0100055	biolink:NamedThing	obsolete positive regulation of phosphatidylserine biosynthetic process by transcription from RNA polymerase II promoter	OBSOLETE. Any transcription from RNA polymerase II promoter process that positively regulates phosphatidylserine biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it represents a GO-CAM model.		cjm	2015-04-02T04:13:19Z		True			biological_process											owl:Class	
GO:0043962	biolink:NamedThing	obsolete negative regulation by host of symbiont adenylate cyclase-mediated signal transduction	OBSOLETE. Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of adenylate cyclase-mediated signal transduction in the symbiont organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl						The reason for obsoletion is that there is no evidence that the host can modulate or regulate a symbiont's signal transduction pathway.					True			biological_process											owl:Class	
GO:0061432	biolink:NamedThing	obsolete regulation of transcription from RNA polymerase II promoter in response to methionine	OBSOLETE. Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a methionine stimulus.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it represents a GO-CAM model.	GO:0006357	dph	2012-02-07T10:33:35Z		True			biological_process											owl:Class	
GO:0030508	biolink:NamedThing	obsolete thiol-disulfide exchange intermediate activity	OBSOLETE. Functions as an exchange intermediate in thiol-disulfide exchange reactions.	tmpzr1t_l9r_go_relaxed.owl	thiol-disulphide exchange intermediate activity|thiol-disulfide exchange intermediate activity|glutaredoxin|thioredoxin					This term was made obsolete because it represents a combination of gene product features and involvement in a biological process.	GO:0015036|GO:0003756				True			molecular_function											owl:Class	
GO:0015029	biolink:NamedThing	obsolete internalization receptor activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	internalization receptor activity					This term was made obsolete because internalization is a process, not a ligand to which a receptor might bind.					True			molecular_function											owl:Class	
GO:0052142	biolink:NamedThing	obsolete chemotaxis within host	OBSOLETE. The directed movement of a motile cell or organism in response to a specific chemical concentration gradient within its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/18819				This term was obsoleted because it represents both a process and a location.					True			biological_process											owl:Class	
GO:0006132	biolink:NamedThing	obsolete dihydrolipoylprotein reduction	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	dihydrolipoylprotein reduction					This term was made obsolete because it represents a molecular function rather than a biological process.	GO:0004148|GO:0022900				True			biological_process											owl:Class	
GO:0015466	biolink:NamedThing	obsolete autolysin activity	OBSOLETE. An agent that can lyse the cell in which it is synthesized.	tmpzr1t_l9r_go_relaxed.owl	autolysin activity					This term was made obsolete because it represents a class of gene products.	GO:0019835				True			molecular_function											owl:Class	
GO:0008552	biolink:NamedThing	obsolete zinc, cadmium, cobalt, nickel, lead-efflux ATPase activity	OBSOLETE. Catalysis of the reaction: Me2+(in) + ATP = Me2+(out) + ADP + phosphate, where Me is Zn2+, Cd2+, Co2+, Ni2+ or Pb2+.	tmpzr1t_l9r_go_relaxed.owl	zinc, cadmium, cobalt, nickel, lead-efflux ATPase activity					This term was made obsolete because it represents more than one molecular function.	GO:0015087|GO:0015086|GO:0005385|GO:0015662|GO:0015099|GO:0015094				True			molecular_function											owl:Class	
GO:0016923	biolink:NamedThing	obsolete ligand-dependent thyroid hormone receptor interactor activity	OBSOLETE. Ligand dependent interaction with the thyroid hormone receptor.	tmpzr1t_l9r_go_relaxed.owl	ligand-dependent thyroid hormone receptor interactor activity|TRIP4					This term was made obsolete because it represents a gene product and not a molecular function.	GO:0046966				True			molecular_function											owl:Class	
GO:0075079	biolink:NamedThing	obsolete positive regulation by host of symbiont receptor-mediated signal transduction	OBSOLETE. Any process in which the host organism activates, maintains or increases the frequency, rate or extent of receptor-mediated signal transduction in the symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl						The reason for obsoletion is that there is no evidence that the host can modulate or regulate a symbiont's signal transduction pathway.					True			biological_process											owl:Class	
GO:0036043	biolink:NamedThing	obsolete microspike	OBSOLETE. A dynamic, actin-rich projection extending from the surface of a migrating animal cell.	tmpzr1t_l9r_go_relaxed.owl	microspike			GO:0044393		This term was made obsolete because it accidentally reused an exisiting id. See replacement term GO:0044393.		bf	2011-12-06T01:31:16Z		True			cellular_component											owl:Class	
GO:1903158	biolink:NamedThing	obsolete L-glutamate transmembrane transporter activity involved in L-glutamate import into cell	OBSOLETE. Any L-glutamate transmembrane transporter activity that is involved in L-glutamate import into cell.	tmpzr1t_l9r_go_relaxed.owl	L-glutamate transmembrane transporter activity involved in L-glutamate import into cell|glutamate/aspartate porter activity involved in L-glutamate import into cell|glutamate/aspartate:sodium symporter activity involved in L-glutamate import into cell					This term was obsoleted at the TermGenie Gatekeeper stage.		dos	2014-07-09T11:56:21Z		True			molecular_function											owl:Class	
GO:0045560	biolink:NamedThing	obsolete regulation of TRAIL receptor biosynthetic process	OBSOLETE. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of the TRAIL (TNF-related apoptosis inducing ligand) receptor.	tmpzr1t_l9r_go_relaxed.owl	regulation of TRAIL receptor biosynthesis|regulation of TRAIL receptor synthesis|regulation of TRAIL receptor anabolism|regulation of TRAIL receptor formation	https://github.com/geneontology/go-ontology/issues/19900				The reason for obsoletion is that those represent specific gene products, and genes annotated to those terms should be annotated to 'regulation of gene expression' or 'regulation of transcription' or some signaling term.					True			biological_process											owl:Class	
GO:0008570	biolink:NamedThing	obsolete myosin ATPase activity	OBSOLETE. Catalysis of the reaction: ATP + H2O = ADP + phosphate. The hydrolysis of ATP by myosin that provides the energy for actomyosin contraction.	tmpzr1t_l9r_go_relaxed.owl	myosin ATPase activity			GO:0000146		This term was made obsolete because it represents a class of gene products, and its definition incorporates process information.	GO:0030048				True			molecular_function											owl:Class	
GO:0052393	biolink:NamedThing	obsolete induction by host of symbiont defense response	OBSOLETE. The activation by an organism of the defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	activation of symbiont defense response					The reason for obsoletion is that there is no evidence that the host can modulate or regulate a symbiont's defense response.					True			biological_process											owl:Class	
GO:0005029	biolink:NamedThing	obsolete CD27 receptor activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	CD27 receptor activity					This term was made obsolete because it describes the receptor type, and not an activity.	GO:0042614				True			molecular_function											owl:Class	
GO:0007551	biolink:NamedThing	obsolete maintenance of dosage compensation	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	maintenance of dosage compensation					This term was made obsolete because it was undefined and because there is no common mechanism of establishment of dosage compensation in different organisms.	GO:0007549				True			biological_process											owl:Class	
GO:0031599	biolink:NamedThing	obsolete ER proteasome regulatory particle	OBSOLETE. The regulatory subcomplex of a proteasome located in the endoplasmic reticulum of a cell.	tmpzr1t_l9r_go_relaxed.owl						This term was made obsolete because there is no evidence in the literature of its existence.					True			cellular_component											owl:Class	
GO:0106039	biolink:NamedThing	obsolete vesicle fusion involved in vesicle assembly	OBSOLETE. A process carried out at the cellular level, which is the final step in vesicle assembly. Vesicle fusion occurs when a newly assembled vesicle closes up, following vesicle vesicle scission (GO:0099050).	tmpzr1t_l9r_go_relaxed.owl						This term was made obsolete becausethat 'fusion' should only be used for two membranes getting joined together, whereas in this case it would be one membrane 'closing/sealing up'.		hjd	2017-07-17T13:56:31Z		True			biological_process											owl:Class	
RO:0002161	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl																									owl:AnnotationProperty	
GO:0009493	biolink:NamedThing	obsolete adrenodoxin-type ferredoxin	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	adrenodoxin-type ferredoxin			GO:0009055		This term was made obsolete because it does not represent a function.					True			molecular_function											owl:Class	
GO:0003077	biolink:NamedThing	obsolete negative regulation of diuresis	OBSOLETE. Any process that reduces the rate of diuresis. Diuresis is the process of renal water excretion.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of diuresis					This term was made obsolete because its definition was inaccurate.	GO:0035811				True			biological_process											owl:Class	
GO:0008148	biolink:NamedThing	obsolete negative transcription elongation factor activity	OBSOLETE. Any activity that decreases the rate of transcription elongation, the addition of ribonucleotides to an RNA molecule following transcription initiation.	tmpzr1t_l9r_go_relaxed.owl	negative transcription elongation factor activity					This term was obsoleted because it is essentially identical to a Process term (specifically the Biological Process term which has been selected as a term to consider for reannotation), i.e. it is defined only in terms of the process it acts in and it does NOT convey any information about the molecular nature of the function or whether the function is based on binding DNA, on interacting with other proteins, or some other mechanism. To transfer all annotations without review, the BP term indicated is considered to be equivalent and thus the only appropriate destination for all annotations. To reannotate to a MF term, you will probably need to revisit the original literature or other primary data because this "MF" term was not defined in terms of mechanism of action and there are multiple possibilities in the revised MF structure. In reannotation, please also consider descendent terms of the suggested MF terms as a more specific term may be more appropriate than the MF terms indicated. Please be aware that you may wish to request a new term if the mechanism of action of this gene product is not yet represented or if you are annotating for an RNAP different than one for which there is a specific suggested term. Also note that if there is no information about how the gene product acts, it may be appropriate to annotate to the root term for molecular_function.	GO:0032785				True			molecular_function											owl:Class	
GO:0003732	biolink:NamedThing	obsolete snRNA cap binding	OBSOLETE. Interacting selectively with the cap structure at the 5' end of a small nuclear RNA molecule.	tmpzr1t_l9r_go_relaxed.owl	snRNA cap binding					This term was made obsolete because the functional distinction for cap binding is the structure of the cap, not the type of RNA it is attached to.	GO:0000339				True			molecular_function											owl:Class	
GO:0003929	biolink:NamedThing	obsolete RAN small monomeric GTPase activity	OBSOLETE. Catalysis of the reaction: GTP + H2O = GDP + phosphate.	tmpzr1t_l9r_go_relaxed.owl	RAN small monomeric GTPase activity			GO:0003924		This term was made obsolete because it represents a gene product.	GO:0006606				True			molecular_function											owl:Class	
GO:0009633	biolink:NamedThing	obsolete drought tolerance	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	drought tolerance					This term was made obsolete because 'tolerance' implies a phenotype rather than a biological process.	GO:0009819|GO:0009414				True			biological_process											owl:Class	
GO:1903819	biolink:NamedThing	obsolete detection of stimulus involved in mitotic cytokinesis checkpoint	OBSOLETE. Any detection of stimulus that is involved in a mitotic cytokinesis checkpoint.	tmpzr1t_l9r_go_relaxed.owl	perception of stimulus involved in mitotic cytokinesis checkpoint|stimulus sensing involved in mitotic cytokinesis checkpoint|stimulus detection involved in mitotic cytokinesis checkpoint	https://github.com/geneontology/go-ontology/issues/20976				This term was obsoleted because it corresponds to a molecular function.		jl	2015-01-19T15:03:16Z		True			biological_process											owl:Class	
GO:0046582	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0003715	biolink:NamedThing	obsolete transcription termination factor activity	OBSOLETE. Any activity that brings about termination of transcription.	tmpzr1t_l9r_go_relaxed.owl	transcriptional termination factor activity|transcription termination factor activity					This term was obsoleted because it is essentially identical to a Process term (specifically the Biological Process term which has been selected as a term to consider for reannotation), i.e. it is defined only in terms of the process it acts in and it does NOT convey any information about the molecular nature of the function or whether the function is based on binding DNA, on interacting with other proteins, or some other mechanism. To transfer all annotations without review, the BP term indicated is considered to be equivalent and thus the only appropriate destination for all annotations. To reannotate to a MF term, you will probably need to revisit the original literature or other primary data because this "MF" term was not defined in terms of mechanism of action and there are multiple possibilities in the revised MF structure. In reannotation, please also consider descendent terms of the suggested MF terms as a more specific term may be more appropriate than the MF terms indicated. Please be aware that you may wish to request a new term if the mechanism of action of this gene product is not yet represented or if you are annotating for an RNAP different than one for which there is a specific suggested term. Also note that if there is no information about how the gene product acts, it may be appropriate to annotate to the root term for molecular_function.	GO:0006353				True			molecular_function											owl:Class	
GO:0004278	biolink:NamedThing	obsolete granzyme B activity	OBSOLETE. Catalysis of the preferential cleavage of Asp-Xaa > Asn-Xaa > Met-Xaa, Ser-Xaa.	tmpzr1t_l9r_go_relaxed.owl	CCP1 proteinase|cytotoxic t-lymphocyte proteinase 2 activity|cytotoxic cell proteinase-1|CTLA1|granzyme G|granzyme B activity|CCPII|granzyme H			GO:0004252		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0075066	biolink:NamedThing	obsolete growth or development of symbiont in host organelle	OBSOLETE. The increase in size or mass of symbiont, or the progression of the symbiont from an initial condition to a later condition, occurring in its host's organelle. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	growth or development of symbiont in host organelle					This term was made obsolete because it contained a conjunction (or).					True			biological_process											owl:Class	
GO:0052206	biolink:NamedThing	obsolete modification of morphology or physiology of other organism via protein secreted by type II secretion system involved in symbiotic interaction	OBSOLETE. The process in which an organism effects a change in the structure or function of a second organism, mediated by a substance secreted by a type II secretion system in the first organism, where the two organisms are in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	modification of morphology or physiology of other organism via protein secreted by type II secretion system during symbiotic interaction					This term was obsoleted because it conflated the process in which a gene product is involved with the secretion system by which it reaches its target.					True			biological_process											owl:Class	
GO:0023011	biolink:NamedThing	obsolete positive regulation of initiation of T cell receptor signaling	OBSOLETE. Any process that activates, maintains or increases the frequency, rate or extent of the initiation of T cell receptor signaling.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of initiation of T cell receptor signalling|positive regulation of initiation of T cell receptor signaling					This term was made obsolete because the meaning of the term is ambiguous.	GO:0050862		2010-02-16T09:30:50Z		True			biological_process											owl:Class	
GO:0030799	biolink:NamedThing	obsolete regulation of cyclic nucleotide metabolic process	OBSOLETE. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving cyclic nucleotides.	tmpzr1t_l9r_go_relaxed.owl	regulation of cyclic nucleotide metabolism					The reason for obsoletion is that this term represents the regulation of a signaling pathway, not regulation of metabolism.					True			biological_process											owl:Class	
GO:0046138	biolink:NamedThing	obsolete coenzyme and prosthetic group biosynthetic process	OBSOLETE. The chemical reactions and pathways resulting in the formation of coenzymes and prosthetic groups.	tmpzr1t_l9r_go_relaxed.owl	coenzyme and prosthetic group formation|coenzyme and prosthetic group biosynthesis|coenzyme and prosthetic group synthesis|coenzyme and prosthetic group biosynthetic process|coenzyme and prosthetic group anabolism					This term was made obsolete because it was replaced by more specific terms.	GO:0051191				True			biological_process											owl:Class	
GO:0007607	biolink:NamedThing	obsolete taste perception	OBSOLETE. The series of events required for the chemical composition of a soluble stimulus to be received and converted to a molecular signal.	tmpzr1t_l9r_go_relaxed.owl	taste perception					This term was made obsolete because it was not clear whether the term applied to the whole process of taste perception or just the sensory transduction stage.	GO:0050909|GO:0050912				True			biological_process											owl:Class	
GO:0043526	biolink:NamedThing	obsolete neuroprotection	OBSOLETE. Any process that modulates the occurrence or rate of cell death by apoptosis in the nervous system. It may stop or prevent or reduce the rate of cell death by apoptosis and it is activated by stress to counteract death signals in central nervous systems. Different neuroprotective mechanisms may be activated to combat distinct types of cellular stress, ERK pathway is one of several neuroprotective mechanisms and it is a model system to study neuronal apoptosis, which may contribute to several neurodegenerative diseases and aging-related neuron loss.	tmpzr1t_l9r_go_relaxed.owl	neuroprotection				Wikipedia:Neuroprotection	This term was made obsolete because it refers to assays rather than processes. If neuron death by apoptosis is assessed, consider using GO:0043523 regulation of neuron apoptotic process. If neuron death is assessed but the cell death modality isn't defined, refer to GO:0070997 neuron death. Where non-neuronal cells are involved, and/or processes other than cell death are described, please use other terms for annotation.					True			biological_process											owl:Class	
GO:0019718	biolink:NamedThing	obsolete rough microsome	OBSOLETE. Vesicular particles formed from disrupted endoplasmic reticulum membranes and studded with ribosomes on the outside.	tmpzr1t_l9r_go_relaxed.owl	rough microsome					This term was made obsolete because it refers to a cell fractionation experimental result and not a bona fide cellular component.	GO:0005791				True			cellular_component											owl:Class	
GO:0030356	biolink:NamedThing	obsolete small cytoplasmic ribonucleoprotein	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	scRNP|small cytoplasmic ribonucleoprotein			GO:1990904		This term was made obsolete because it describes a cellular component rather than a molecular function.					True			molecular_function											owl:Class	
GO:0006840	biolink:NamedThing	obsolete mitochondrial alpha-ketoglutarate/malate transport	OBSOLETE. The directed movement of alpha-ketoglutarate and malate into, out of or within a mitochondrion.	tmpzr1t_l9r_go_relaxed.owl	mitochondrial alpha-ketoglutarate/malate transport|mitochondrial oxoglutarate/malate transport					This term was made obsolete because it represents a function rather than a process.	GO:0015742|GO:0015367|GO:0015743|GO:0006839				True			biological_process											owl:Class	
GO:0004203	biolink:NamedThing	obsolete caspase-4 activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	caspase-4 activity			GO:0004197		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0085024	biolink:NamedThing	obsolete modification by symbiont of host morphology or physiology via protein secreted by Sec complex	OBSOLETE. The process in which an organism (symbiont) effects a change in the structure or function of its host organism, mediated by a substance secreted by the Sec complex in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	modification by symbiont of host morphology or physiology via protein secreted by the Sec secretion system					This term was obsoleted because it conflated the process in which a gene product is involved with the secretion system by which it reaches its target.		jl	2010-07-09T03:44:31Z		True			biological_process											owl:Class	
GO:0100065	biolink:NamedThing	obsolete negative regulation of leucine import by transcription from RNA polymerase II promoter	OBSOLETE. Any transcription from RNA polymerase II promoter process that negatively regulates leucine import.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it represents a GO-CAM model.		cjm	2015-04-02T04:13:19Z		True			biological_process											owl:Class	
GO:0090723	biolink:NamedThing	obsolete growth cone part	OBSOLETE. Any constituent part of a growth cone, the migrating motile tip of a growing nerve cell axon or dendrite.	tmpzr1t_l9r_go_relaxed.owl							GO:0030426	tb	2016-11-18T09:36:19Z		True			cellular_component											owl:Class	
GO:0046268	biolink:NamedThing	obsolete toluene-4-sulfonate biosynthetic process	OBSOLETE. The chemical reactions and pathways resulting in the formation of toluene-4-sulfonate, 4-methylbenzenesulfonate, the anion of sulfonic acid attached to a methylbenzene molecule.	tmpzr1t_l9r_go_relaxed.owl	toluene-4-sulphonate biosynthesis|toluene-4-sulfonate biosynthesis|4-toluenesulfonate biosynthesis|toluene-4-sulfonate biosynthetic process|toluene-4-sulfonate synthesis|toluene-4-sulfonate anabolism|toluene-4-sulfonate formation|4-toluenesulfonate biosynthetic process|toluene-4-sulphonate biosynthetic process			GO:0018972		This term was made obsolete because toluene-4-sulfonate is not synthesized by living organisms, and GO does not cover non-biological processes.					True			biological_process											owl:Class	
GO:0042079	biolink:NamedThing	obsolete GPI/GSI anchor metabolic process	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	GPI/GSI anchor metabolic process					This term was made obsolete because it is a composite term that represents two individual processes.	GO:0006505|GO:0042081				True			biological_process											owl:Class	
GO:0071510	biolink:NamedThing	obsolete activation of MAPKKK activity involved in conjugation with cellular fusion	OBSOLETE. Any process that initiates the activity of the inactive enzyme MAP kinase kinase kinase in the context of conjugation with cellular fusion.	tmpzr1t_l9r_go_relaxed.owl	conjugation with cellular fusion, activation of MAP kinase kinase kinase activity|activation of MAP kinase kinase kinase activity during conjugation with cellular fusion|activation of MAPKKK activity involved in mating response|conjugation with cellular fusion, activation of MAPKKK activity	https://github.com/geneontology/go-ontology/issues/20242				This term was obsoleted because it represents a GO-CAM model.		mah	2010-01-05T02:10:18Z		True			biological_process											owl:Class	
GO:0015258	biolink:NamedThing	obsolete gluconate channel activity	OBSOLETE. This term was not defined before being made obsolete.	tmpzr1t_l9r_go_relaxed.owl	gluconate channel activity					This term was made obsolete because this solute is transported by an active transporter rather than a channel.					True			molecular_function											owl:Class	
GO:0043075	biolink:NamedThing	obsolete sperm cell nucleus (sensu Magnoliophyta)	OBSOLETE. The nucleus of a plant pollen cell, the male gamete, and its descendents.	tmpzr1t_l9r_go_relaxed.owl	pollen germ cell nucleus|pollen germ-cell nucleus|sperm cell nucleus (sensu Magnoliophyta)					This term was made obsolete because the definition was incorrect.	GO:0048555				True			cellular_component											owl:Class	
GO:2000681	biolink:NamedThing	obsolete negative regulation of rubidium ion transport	OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of rubidium ion transport.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of rubidium cation transport|negative regulation of Rb+ transport					This term has been obsoleted because it represents an assay, and not a physiological process.		bf	2011-05-10T10:54:34Z		True			biological_process											owl:Class	
GO:0005613	biolink:NamedThing	obsolete laminin receptor protein	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	laminin receptor protein					This term was made obsolete because it is out of date. It seems to be referring to the non-integrin 34/67kDa laminin receptor, which new research has shown to actually be a ribosomal protein of the SP2 family.	GO:0008305				True			cellular_component											owl:Class	
GO:0006912	biolink:NamedThing	obsolete phagosome formation	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	phagosome formation					This term was made obsolete because of the ambiguity in its meaning.	GO:0001845|GO:0006911				True			biological_process											owl:Class	
GO:0000764	biolink:NamedThing	obsolete cellular morphogenesis involved in pheromone-induced unidirectional conjugation	OBSOLETE. The change in form (cell shape and size) that contributes to sexual reproduction in order to facilitate direct contact between the compatible mating types in organisms that undergo pheromone-induced unidirectional conjugation.	tmpzr1t_l9r_go_relaxed.owl	cellular morphogenesis involved in pheromone-induced unidirectional conjugation|cellular morphogenesis during pheromone-induced unidirectional					This term was made obsolete because unidirectional conjugation occurs only in prokaryotes, which do not undergo morphogenetic changes associated with conjugation. In short, the process described by this term does not occur.					True			biological_process											owl:Class	
GO:0048746	biolink:NamedThing	obsolete smooth muscle fiber development	OBSOLETE. The process whose specific outcome is the progression of smooth muscle fiber over time, from its formation to the mature structure.	tmpzr1t_l9r_go_relaxed.owl	smooth muscle fibre development|smooth muscle fiber development					This term was made obsolete because smooth muscle does not have fibers.					True			biological_process											owl:Class	
GO:1990496	biolink:NamedThing	obsolete regulation of actin filament organization involved in mitotic cytokinetic actomyosin contractile ring assembly	OBSOLETE. An actin filament organization process that contributes to regulation of actomyosin contractile ring assembly during mitotic cytokinesis.	tmpzr1t_l9r_go_relaxed.owl	regulation of actin filament organization involved in mitotic cytokinetic actomyosin contractile ring assembly					This term was obsoleted at the TermGenie Gatekeeper stage.		al	2014-09-25T09:21:57Z		True			biological_process											owl:Class	
GO:0016850	biolink:NamedThing	obsolete other lyase activity	OBSOLETE. A grouping term for lyases that cannot be more accurately categorized.	tmpzr1t_l9r_go_relaxed.owl	other lyase activity					This term was made obsolete because it was an unnecessary grouping term.	GO:0016829				True			molecular_function											owl:Class	
GO:0008472	biolink:NamedThing	obsolete metallocarboxypeptidase D activity	OBSOLETE. Catalysis of the reaction: peptidyl-L-lysine (or peptidyl-L-arginine) + H2O = peptide + L-lysine (or L-arginine). Function is activated by Co2+; inhibited by guanidinoethylmercaptosuccinic acid.	tmpzr1t_l9r_go_relaxed.owl	gp180 (duck)|metallocarboxypeptidase D activity|carboxypeptidase D (cattle, human, mouse, rat)			GO:0004181		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0000826	biolink:NamedThing	obsolete inositol pyrophosphate synthase activity	OBSOLETE. Catalysis of the phosphorylation of inositol phosphates which possess diphosphate bonds.	tmpzr1t_l9r_go_relaxed.owl	inositol pyrophosphate synthase activity|inositol diphosphate synthase activity					This term was made obsolete because it is incorrectly defined; 'inositol pyrophosphate' is a inositol derivative to which one (or more) pyrophosphate moieties are attached. 'Inositol pyrophosphate synthase' refers to a class of enzymes that catalyze various different reactions that result in the formation of an IP, so one cannot formulate a general reaction for them.	GO:0052746				True			molecular_function											owl:Class	
GO:1990242	biolink:NamedThing	obsolete innate immune response complex	OBSOLETE. A protein complex involved in the innate immune response.	tmpzr1t_l9r_go_relaxed.owl	innate immune response complex					This term was obsoleted at the TermGenie Gatekeeper stage.		bhm	2013-11-26T13:36:52Z		True			cellular_component											owl:Class	
GO:0033160	biolink:NamedThing	obsolete positive regulation of protein import into nucleus, translocation	OBSOLETE. Any process that activates or increases the vectorial transfer of a protein from the cytoplasm into the nucleus, across the nuclear membrane.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of protein import into cell nucleus, translocation					This term has been obsoleted because it represents a substep of the parent (GO:0006606 protein import into nucleus), has been incorrectly used.					True			biological_process											owl:Class	
GO:0060821	biolink:NamedThing	obsolete inactivation of X chromosome by DNA methylation	OBSOLETE. Compensating for the two-fold variation in X-chromosome:autosome ratios between sexes by a global inactivation of all, or most of, the genes on one of the X-chromosomes in the XX sex by a mechanism of DNA methylation.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/22023				This term was obsoleted because it represents a molecular function.	GO:0009048|GO:0035514	dph	2009-08-11T11:02:19Z		True			biological_process											owl:Class	
GO:0023036	biolink:NamedThing	obsolete initiation of signal transduction	OBSOLETE. The process in which a signal causes activation of a receptor, for example, via a conformation change.	tmpzr1t_l9r_go_relaxed.owl	initiation of signal transduction|signal reception					This term was made obsolete because the meaning of the term is ambiguous. Note that this term was intended for the annotation of both ligands and receptors.	GO:0048018|GO:0038023|GO:0007165		2010-02-16T09:30:50Z		True			biological_process											owl:Class	
GO:0016086	biolink:NamedThing	obsolete allatostatin	OBSOLETE. Peptide hormones produced by the corpora allata of insects that reversibly inhibit the production of juvenile hormone.	tmpzr1t_l9r_go_relaxed.owl	allatostatin					This term was made obsolete because it refers to a gene product.	GO:0045968|GO:0005102				True			molecular_function											owl:Class	
GO:0075176	biolink:NamedThing	obsolete negative regulation of cAMP-mediated signaling in response to host	OBSOLETE. Any process in which the symbiont organism stops, prevents, or reduces the frequency, rate or extent of its cAMP-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of cAMP-mediated signal transduction in response to host|negative regulation of cAMP-mediated signalling in response to host|negative regulation of symbiont cAMP-mediated signal transduction in response to host					This term was obsoleted because there is no evidence that this process exists.					True			biological_process											owl:Class	
GO:0015219	biolink:NamedThing	obsolete protein-DNA complex transmembrane transporter activity	OBSOLETE. Enables the transfer of protein-DNA complexes from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	DNA-protein complex transmembrane transporter activity	https://github.com/geneontology/go-ontology/issues/17005				This term was obsoleted because there is no experimental evidence that this function exists.					True			molecular_function											owl:Class	
GO:0000265	biolink:NamedThing	obsolete heterotrimeric G-protein GTPase, gamma-subunit	OBSOLETE. Smallest subunit of a heterotrimeric G-protein GTPase; associates tightly with the beta subunit.	tmpzr1t_l9r_go_relaxed.owl	heterotrimeric G-protein GTPase, gamma-subunit					This term was made obsolete because it does not represent a molecular function.	GO:0005834|GO:0003924				True			molecular_function											owl:Class	
GO:1990363	biolink:NamedThing	obsolete response to hydrolysate	OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of hydrolysate (any product of hydrolysis).	tmpzr1t_l9r_go_relaxed.owl	response to hydrolysate					This term was obsoleted at the TermGenie Gatekeeper stage.		tt	2014-04-23T22:12:24Z		True			biological_process											owl:Class	
GO:0052341	biolink:NamedThing	obsolete catabolism by organism of cell wall pectin in other organism involved in symbiotic interaction	OBSOLETE. The chemical reactions and pathways performed by an organism resulting in the breakdown of pectin in the cell wall of a second organism, where the two organisms are in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	catabolism by organism of cell wall pectin in other organism during symbiotic interaction					This term was obsoleted because it represents an unnecessary grouping class.					True			biological_process											owl:Class	
GO:0021868	biolink:NamedThing	obsolete ventricular zone cell-producing asymmetric radial glial cell division in forebrain	OBSOLETE. The unequal mitotic division of a forebrain radial glial cell that gives rise to a radial glial cell and a ventricular zone cell.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it represents a GO-CAM model.					True			biological_process											owl:Class	
GO:0102192	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052377	biolink:NamedThing	obsolete evasion or tolerance by organism of symbiont-produced phytoalexins	OBSOLETE. The process by which an organism avoids the effects of phytoalexins produced as a defense response by the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	evasion or tolerance by organism of symbiont phytoalexins|symbiont phytoalexin detoxification|evasion or tolerance of phytoalexins produced by symbiont in response to organism|evasion or tolerance by organism of symbiont-produced phytoalexins					This term was made obsolete because it does not represent a real biological process.					True			biological_process											owl:Class	
GO:0004874	biolink:NamedThing	obsolete aryl hydrocarbon receptor activity	OBSOLETE. Combining with an aryl hydrocarbon and transmitting the signal to initiate a change in cell activity. The aryl hydrocarbon receptor is a ligand-activated transcription factor which translocates to the nucleus to activate transcription upon ligand-binding.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/16732				This term was obsoleted because it represents a gene product.					True			molecular_function											owl:Class	
GO:1900537	biolink:NamedThing	obsolete negative regulation of glucose homeostasis	OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of glucose homeostasis.	tmpzr1t_l9r_go_relaxed.owl	inhibition of glucose homeostasis|downregulation of glucose homeostasis|down regulation of glucose homeostasis|negative regulation of glucose homeostasis|down-regulation of glucose homeostasis					This term was obsoleted at the TermGenie Gatekeeper stage.		hjd	2012-05-10T06:53:14Z		True			biological_process											owl:Class	
GO:0006255	biolink:NamedThing	obsolete UDP reduction	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	UDP reduction					This term was made obsolete because it represents a molecular function rather than a biological process.	GO:0051062				True			biological_process											owl:Class	
RO:0002315	biolink:NamedThing	results in acquisition of features of		tmpzr1t_l9r_go_relaxed.owl					RO:0002315									external									results_in_acquisition_of_features_of			
GO:0008546	biolink:NamedThing	obsolete microtubule/chromatin interaction	OBSOLETE. Physical interaction between microtubules and chromatin via DNA binding proteins.	tmpzr1t_l9r_go_relaxed.owl	microtubule/chromatin interaction					This term was made obsolete because it represents a molecular function.	GO:0003677|GO:0030674|GO:0003682|GO:0008017				True			biological_process											owl:Class	
GO:0008423	biolink:NamedThing	obsolete bleomycin hydrolase activity	OBSOLETE. Catalysis of the inactivation of bleomycin B2 (a cytotoxic glycometallopeptide) by hydrolysis of a peptide bond of beta-aminoalanine, but also shows general aminopeptidase activity. The specificity varies somewhat with source, but amino acid arylamides of Met, Leu and Ala are preferred.	tmpzr1t_l9r_go_relaxed.owl	bleomycin hydrolase activity|aminopeptidase C (Lactococcus lactis)			GO:0004197		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:1990958	biolink:NamedThing	obsolete response to thyrotropin-releasing hormone	OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a thyrotropin-releasing hormone (TRH) stimulus. TRH increases the secretion of thyroid-stimulating hormone by the anterior pituitary.	tmpzr1t_l9r_go_relaxed.owl	response to TRH					This term was obsoleted at the TermGenie Gatekeeper stage.		sl	2016-06-06T21:07:34Z		True			biological_process											owl:Class	
has_target_start_location	biolink:NamedThing	has target start location		tmpzr1t_l9r_go_relaxed.owl					RO:0002338									external									has_target_start_location			
GO:0004929	biolink:NamedThing	obsolete frizzled-2 receptor activity	OBSOLETE. Combining with to a member of the Wnt-family of signaling molecules to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	frizzled-2 receptor activity			GO:0042813		This term was made obsolete because it represents a gene product rather than an activity.	GO:0007223				True			molecular_function											owl:Class	
GO:0045297	biolink:NamedThing	obsolete post-mating behavior	OBSOLETE. The specific behavior of an organism following mating.	tmpzr1t_l9r_go_relaxed.owl	post-mating behaviour					This term was obsoleted because it was not precisely defined.					True			biological_process											owl:Class	
GO:0039647	biolink:NamedThing	obsolete suppression by virus of host poly(A)-binding protein activity	OBSOLETE. Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host poly(A)-binding protein (PABP) activity. PABP binds to the poly(A) tail of mRNA to facilitate translation.	tmpzr1t_l9r_go_relaxed.owl	suppression by virus of host PABP activity|inhibition of host poly(A)-binding protein by virus	https://github.com/geneontology/go-ontology/issues/22163				This term was obsoleted because it represents a molecular function.	GO:0039604	bf	2012-10-09T15:14:07Z		True			biological_process											owl:Class	
GO:0005014	biolink:NamedThing	obsolete neurotrophin TRKA receptor activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	neurotrophin TRKA receptor activity					This term was made obsolete because it represents a gene product.	GO:0004714|GO:0007165|GO:0043121|GO:0048406				True			molecular_function											owl:Class	
GO:0046617	biolink:NamedThing	obsolete nucleolar size increase (sensu Saccharomyces)	OBSOLETE. The process of nucleolar expansion, as seen in Saccharomyces.	tmpzr1t_l9r_go_relaxed.owl	nucleolar size increase (sensu Saccharomyces)					This term was made obsolete because it does not describe a biological process.	GO:0007576|GO:0007571				True			biological_process											owl:Class	
GO:0075078	biolink:NamedThing	obsolete modulation by host of symbiont receptor-mediated signal transduction	OBSOLETE. Any process in which the host organism modulates the frequency, rate or extent of receptor-mediated signal transduction in the symbiont. The receptor is defined as a protein on the cell membrane or within the cytoplasm or cell nucleus that binds to a specific molecule (a ligand) such as a neurotransmitter or a hormone or other substance, and initiates the cellular response to the ligand. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl						The reason for obsoletion is that there is no evidence that the host can modulate or regulate a symbiont's signal transduction pathway.					True			biological_process											owl:Class	
GO:1900389	biolink:NamedThing	obsolete regulation of glucose import by regulation of transcription from RNA polymerase II promoter	OBSOLETE. A regulation of transcription from RNA polymerase II promoter that results in regulation of glucose import.	tmpzr1t_l9r_go_relaxed.owl	regulation of glucose uptake by regulation of transcription from RNA polymerase II promoter					This term was obsoleted because it represents a GO-CAM model.		mah	2012-04-18T03:52:43Z		True			biological_process											owl:Class	
GO:0046591	biolink:NamedThing	obsolete embryonic leg joint morphogenesis	OBSOLETE. The process, occurring in the embryo, by which the anatomical structures of the leg joint are generated and organized. A leg joint is a flexible region that separates the rigid sections of a leg to allow movement in a controlled manner.	tmpzr1t_l9r_go_relaxed.owl	embryonic leg joint morphogenesis					This term was made obsolete because leg is a mechano-functional grouping, and having both 'leg morphogenesis' and 'hindlimb morphogenesis' terms causes errors in querying.	GO:0036023				True			biological_process											owl:Class	
GO:0019936	biolink:NamedThing	obsolete inositol phospholipid-mediated signaling	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	inositol phospholipid-mediated signaling|inositol phospholipid-mediated signalling					This term was made obsolete because it did not adequately describe phosphoinositide-mediated signaling.	GO:0048017|GO:0048016				True			biological_process											owl:Class	
GO:0052246	biolink:NamedThing	obsolete positive energy taxis on or near other organism involved in symbiotic interaction	OBSOLETE. The directed movement of a motile cell or organism on or near a second organism towards a higher level of a physical stimulus involved in energy generation, such as light, oxygen, and oxidizable substrates, where the two organisms are in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	positive energy taxis on or near other organism during symbiotic interaction	https://github.com/geneontology/go-ontology/issues/18819				This term was obsoleted because it represents both a process and a location.					True			biological_process											owl:Class	
GO:0050516	biolink:NamedThing	obsolete inositol polyphosphate multikinase activity	OBSOLETE. Catalysis of the reactions: ATP + 1D-myo-inositol 1,4,5-trisphosphate = ADP + 1D-myo-inositol 1,4,5,6-tetrakisphosphate, and ATP + 1D-myo-inositol 1,4,5,6-tetrakisphosphate = ADP + 1D-myo-inositol 1,3,4,5,6-pentakisphosphate.	tmpzr1t_l9r_go_relaxed.owl	IP3/IP4 6-/3-kinase activity|inositol-polyphosphate multikinase activity|ATP:1D-myo-inositol-1,4,5-trisphosphate 6-phosphotransferase activity|inositol polyphosphate multikinase activity|IpmK|AtIpk2alpha|AtIpk2beta|ArgRIII|IP3/IP4 dual-specificity 6-/3-kinase activity|AtIpk2-alpha activity|IpK2 activity|inositol polyphosphate 6-/3-/5-kinase activity|AtIpk2-beta activity				EC:2.7.1.151|MetaCyc:2.7.1.151-RXN	This term was made obsolete because this activity is currently defined as catalyzing two sequential reactions based on a gene product. However, "inositol polyphosphate multikinase activity" in some organisms can catalyze additional reactions. In addition, the reactions listed in the definition can be catalyzed independently by other gene products.					True			molecular_function											owl:Class	
GO:0038078	biolink:NamedThing	obsolete MAP kinase phosphatase activity involved in regulation of innate immune response	OBSOLETE. Catalysis of the reaction: a phosphorylated MAP kinase + H2O = a MAP kinase + phosphate, where the MAP kinase (MAPK) is part of a MAPK signaling cascade that contributes to an innate immune response.	tmpzr1t_l9r_go_relaxed.owl	MAPK phosphatase activity involved in regulation of innate immune response	https://github.com/geneontology/go-ontology/issues/21552				This term was obsoleted because it represents a biological process within the molecular function branch.		bf	2012-01-26T02:35:52Z		True			molecular_function											owl:Class	
GO:0018367	biolink:NamedThing	obsolete free L-amino acid racemization	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	free L-amino acid racemization					This term was made obsolete because it is not clear that this process occurs.	GO:0006520				True			biological_process											owl:Class	
GO:0022865	biolink:NamedThing	obsolete transmembrane electron transfer carrier	OBSOLETE. Enables electron flow across a biological membrane, from donors localized on one side of the membrane to acceptors localized on the other side. These systems contribute to or subtract from the membrane potential, depending on the direction of electron flow. They are therefore important to cellular energetics.	tmpzr1t_l9r_go_relaxed.owl					TC:5	The reason for obsoletion is that the term does not represent a molecular function but rather a process.					True			molecular_function											owl:Class	
GO:0001061	biolink:NamedThing	obsolete bacterial-type RNA polymerase activity	OBSOLETE. Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template that contains a bacterial-type specific promoter to direct initiation and catalyses DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/16738		GO:0003899		This term was obsoleted because the activity is the same as its parent.		krc	2010-10-19T03:36:01Z		True			molecular_function											owl:Class	
GO:0061777	biolink:NamedThing	obsolete DNA clamp activity	OBSOLETE. A DNA binding activity in which a protein complex interacts selectively and non-covalently with single DNA duplex to tightly encircle the DNA.	tmpzr1t_l9r_go_relaxed.owl						The reason for obsoletion is that the term captures the structure of a complex, not a specific function.		dph	2016-07-13T13:15:24Z		True			molecular_function											owl:Class	
GO:0100016	biolink:NamedThing	obsolete regulation of thiamine biosynthetic process by transcription from RNA polymerase II promoter	OBSOLETE. Any transcription from RNA polymerase II promoter process that regulates thiamine biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it represents a GO-CAM model.		cjm	2015-04-02T04:13:19Z		True			biological_process											owl:Class	
GO:0008538	biolink:NamedThing	obsolete proteasome activator activity	OBSOLETE. Catalysis of the activation of the proteasome, a large multisubunit complex which performs regulated ubiquitin-dependent cytosolic and nuclear proteolysis.	tmpzr1t_l9r_go_relaxed.owl	proteasome activator activity|PA28					The term was made obsolete because 'proteasome' is not a valid molecular function term.	GO:0061133|GO:0061136				True			molecular_function											owl:Class	
GO:0006134	biolink:NamedThing	obsolete dihydrobiopterin reduction	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	dihydrobiopterin reduction					This term was made obsolete because it represents a molecular function rather than a biological process.	GO:0022900|GO:0051066|GO:0047040				True			biological_process											owl:Class	
GO:0098019	biolink:NamedThing	obsolete virus tail, major subunit	OBSOLETE. The part of the viral tail that comprises the most common subunit type.	tmpzr1t_l9r_go_relaxed.owl	major tail protein					The reason for obsoletion is that these are not precise structures: major (most abundant) and minor subunits of viral tails vary in different viruses/phages.		bm	2012-07-19T11:32:55Z		True			cellular_component											owl:Class	
GO:0016341	biolink:NamedThing	obsolete other collagen	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	other collagen			GO:0005581		This term was made obsolete because it is a redundant grouping term.					True			cellular_component											owl:Class	
GO:0030052	biolink:NamedThing	obsolete parvulin	OBSOLETE. A peptidyl-prolyl isomerase isolated from Escherichia coli. It does not have any function as an immunophilin.	tmpzr1t_l9r_go_relaxed.owl	parvulin			GO:0003755		This term was made obsolete because it describes a gene product.					True			molecular_function											owl:Class	
GO:0045802	biolink:NamedThing	obsolete negative regulation of cytoskeleton	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the organization, biogenesis or maintenance of the cytoskeleton.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of cytoskeleton					This term was made obsolete because cytoskeleton is not a process, so the term made no sense.	GO:0007010				True			biological_process											owl:Class	
GO:0072430	biolink:NamedThing	obsolete detection of DNA damage stimulus involved in mitotic G1 DNA damage checkpoint	OBSOLETE. The series of events in which information about damage to DNA is received and converted into a molecular signal, contributing to a mitotic cell cycle G1/S transition DNA damage checkpoint.	tmpzr1t_l9r_go_relaxed.owl	mitotic cell cycle G1/S transition DNA damage checkpoint sensor mechanism|mitotic cell cycle G1/S transition DNA damage checkpoint sensor process|sensing involved in mitotic cell cycle G1/S transition DNA damage checkpoint|detection of DNA damage stimulus involved in mitotic cell cycle G1/S transition DNA damage checkpoint	https://github.com/geneontology/go-ontology/issues/20976				This term was obsoleted because it corresponds to a molecular function.		mah	2010-12-08T04:37:40Z		True			biological_process											owl:Class	
GO:0030829	biolink:NamedThing	obsolete regulation of cGMP catabolic process	OBSOLETE. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of cGMP.	tmpzr1t_l9r_go_relaxed.owl	regulation of cGMP breakdown|regulation of cGMP catabolism|regulation of cGMP degradation					The reason for obsoletion is that this term represent the regulation of a signaling pathway,  not regulation of metabolism.					True			biological_process											owl:Class	
GO:1902720	biolink:NamedThing	obsolete intracellular sequestering of copper ion	OBSOLETE. The process of binding or confining copper ions in an intracellular area such that they are separated from other components of a biological system.	tmpzr1t_l9r_go_relaxed.owl	intracellular sequestering of copper ion					This term was obsoleted at the TermGenie Gatekeeper stage.		mr	2014-02-24T16:09:18Z		True			biological_process											owl:Class	
GO:0030441	biolink:NamedThing	obsolete activation of MAPKKK during sporulation (sensu Fungi)	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	activation of MAPKKK during sporulation (sensu Fungi)					This term was made obsolete because it is a gene product specific term.					True			biological_process											owl:Class	
GO:0075087	biolink:NamedThing	obsolete modulation by host of symbiont G protein-coupled receptor signal transduction	OBSOLETE. Any process in which the host organism modulates the frequency, rate or extent of the symbiont G protein-coupled receptor signal transduction. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	modulation by host of symbiont G-protein coupled receptor protein signal transduction					The reason for obsoletion is that there is no evidence that the host can modulate or regulate a symbiont's signal transduction pathway.					True			biological_process											owl:Class	
GO:0010503	biolink:NamedThing	obsolete negative regulation of cell cycle arrest in response to nitrogen starvation	OBSOLETE. Any process that stops, prevents or reduces the frequency or rate of cell cycle arrest in response to nitrogen starvation.	tmpzr1t_l9r_go_relaxed.owl						This term was made obsolete because it is superfluous, as only the more specific 'mitotic G1 cell cycle arrest in response to nitrogen starvation' has been observed.					True			biological_process											owl:Class	
GO:0052242	biolink:NamedThing	obsolete chemotaxis in other organism involved in symbiotic interaction	OBSOLETE. The directed movement of a motile cell or organism in response to a specific chemical concentration gradient within a second organism, where the two organisms are in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	chemotaxis within other organism during symbiotic interaction|chemotaxis in other organism during symbiotic interaction	https://github.com/geneontology/go-ontology/issues/18819				This term was obsoleted because it represents both a process and a location.					True			biological_process											owl:Class	
GO:0008945	biolink:NamedThing	obsolete oligopeptidase B activity	OBSOLETE. Catalysis of the hydrolysis of Arg-Xaa and Lys-Xaa bonds in oligopeptides, even when P1' residue is proline.	tmpzr1t_l9r_go_relaxed.owl	oligopeptidase B activity|Escherichia coli alkaline proteinase II|protease II activity			GO:0004252		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0051187	biolink:NamedThing	obsolete cofactor catabolic process	OBSOLETE. The chemical reactions and pathways resulting in the breakdown of a cofactor, a substance that is required for the activity of an enzyme or other protein.	tmpzr1t_l9r_go_relaxed.owl	cofactor breakdown|cofactor catabolism|cofactor degradation					1. Making inferences in GO about compounds based on the cofactor role curated by ChEBI creates relationships that are not always true which violates ontological principles for GO; therefore we will cease making these inferences. 2. It is not meaningful to group metabolic processes that are not all chemically related by the fact that they may be used as a cofactor.					True			biological_process											owl:Class	
GO:0005203	biolink:NamedThing	obsolete proteoglycan	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	proteoglycan					This term was made obsolete because it describes the composition (i.e. proteoglycan) of a gene product, not a molecular function.					True			molecular_function											owl:Class	
GO:0001007	biolink:NamedThing	obsolete transcription factor activity, RNA polymerase III transcription factor binding	OBSOLETE. Binding to an RNA polymerase III transcription factor, which may be a single protein or a complex, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well.	tmpzr1t_l9r_go_relaxed.owl	RNA polymerase III transcription factor binding transcription factor activity					This term was obsoleted because it represents two separate functions. The corresponding 'binding' term should be used in combination with a transcription regulator activity child.		krc	2010-08-18T06:24:07Z		True			molecular_function											owl:Class	
GO:0023042	biolink:NamedThing	obsolete signaling via protein/peptide mediator	OBSOLETE. The process in which information is sent from one location to another, within a living organism or between living organisms, via a protein/peptide mediator.	tmpzr1t_l9r_go_relaxed.owl	signaling via protein/peptide mediator|signalling via protein/peptide mediator					This term was made obsolete because the meaning of the term is ambiguous.	GO:0023052		2010-02-16T09:30:50Z		True			biological_process											owl:Class	
GO:0004239	biolink:NamedThing	obsolete methionyl aminopeptidase activity	OBSOLETE. Catalysis of the release of N-terminal amino acids, preferentially methionine, from peptides and arylamides.	tmpzr1t_l9r_go_relaxed.owl	methionine aminopeptidase activity|MAP|L-methionine aminopeptidase activity|methionyl aminopeptidase activity|peptidase M activity				MetaCyc:3.4.11.18-RXN|EC:3.4.11.18	This term was made obsolete because it represents a gene product.	GO:0004177|GO:0008235|GO:0070084				True			molecular_function											owl:Class	
GO:0080125	biolink:NamedThing	obsolete multicellular structure septum development	OBSOLETE. The process whose specific outcome is the progression of the multicellular structure septum over time, from its formation to the mature structure. The multicellular structure septum is the thin partition or membrane that divides a cavity or a mass of tissue.	tmpzr1t_l9r_go_relaxed.owl						This term was made obsolete because it is not a useful grouping term.		dhl	2009-04-28T04:31:14Z		True			biological_process											owl:Class	
GO:0008533	biolink:NamedThing	obsolete astacin activity	OBSOLETE. Catalysis of the hydrolysis of peptide bonds in substrates containing five or more amino acids, preferentially with Ala in P1', and Pro in P2'.	tmpzr1t_l9r_go_relaxed.owl	Astacus proteinase activity|astacus proteinase activity|astacin activity|crayfish small-molecule proteinase activity			GO:0004222		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0030637	biolink:NamedThing	obsolete acetate derivative catabolic process	OBSOLETE. The chemical reactions and pathways resulting in the breakdown of derivatives of acetic acid.	tmpzr1t_l9r_go_relaxed.owl	acetate derivative breakdown|acetate derivative degradation|acetate derivative catabolic process|acetate derivative catabolism					This term was made obsolete because it is an unnecessary grouping term and has been replaced by terms to describe metabolism of specific compounds.					True			biological_process											owl:Class	
GO:0052222	biolink:NamedThing	obsolete negative aerotaxis in environment of other organism involved in symbiotic interaction	OBSOLETE. The directed movement of a motile cell or organism towards a lower concentration of environmental oxygen on, within or near a second organism, where the two organisms are in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	negative aerotaxis in environment of other organism during symbiotic interaction|negative aerotaxis in response to environment of other organism	https://github.com/geneontology/go-ontology/issues/18819				This term was obsoleted because it represents both a process and a location.					True			biological_process											owl:Class	
GO:1990977	biolink:NamedThing	obsolete negative regulation of mitotic DNA replication initiation from late origin	OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of firing from a late origin of replication involved in mitotic DNA replication.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted at the TermGenie Gatekeeper stage.		al	2016-07-11T14:56:38Z		True			biological_process											owl:Class	
GO:0019833	biolink:NamedThing	obsolete ice nucleation activity	OBSOLETE. Catalysis of the formation of ice crystals in extracellular fluid at relatively high temperatures (up to -2 degrees C) to protect the organism from damage by intracellular ice formation. Ice nucleation proteins function by binding an ice crystal and then encouraging it to form larger crystals. Ice nucleation is a chemical process but these proteins can positively regulate it. There are two different uses of ice nucleation proteins: bacteria secrete them extracellularly to cause a host organism's cells to freeze and die, and fish use them to protect themselves from intracellular ice formation.	tmpzr1t_l9r_go_relaxed.owl	ice nucleation activity					This term was made obsolete because it represents a biological process.	GO:0042309|GO:0050825				True			molecular_function											owl:Class	
GO:0046212	biolink:NamedThing	obsolete methyl ethyl ketone biosynthetic process	OBSOLETE. The chemical reactions and pathways resulting in the formation of methyl ethyl ketone, a clear, colorless liquid with a fragrant, mint-like odor. It is used as a solvent and in making plastics, textiles and paints.	tmpzr1t_l9r_go_relaxed.owl	methyl ethyl ketone biosynthetic process|methyl ethyl ketone anabolism|methyl ethyl ketone synthesis|methyl ethyl ketone formation|methyl ethyl ketone biosynthesis			GO:0018928		This term was made obsolete because methyl ethyl ketone is not synthesized by living organisms and GO does not cover non-biological processes.					True			biological_process											owl:Class	
GO:0004987	biolink:NamedThing	obsolete kappa-opioid receptor activity	OBSOLETE. Combining with an opioid to initiate a change in cell activity, with the pharmacological characteristics of kappa-opioid receptors, including high affinity for dynorphins.	tmpzr1t_l9r_go_relaxed.owl	kappa-opioid receptor activity				Wikipedia:Kappa_Opioid_receptor	This term was made obsolete because the receptor is defined based on its pharmacological properties.	GO:0038048				True			molecular_function											owl:Class	
GO:1904013	biolink:NamedThing	obsolete xenon atom binding	OBSOLETE. Binding to xenon atom.	tmpzr1t_l9r_go_relaxed.owl						The reason for obsoletion is that binding to xenon does not have physiological relevance.		sl	2015-03-06T19:07:43Z		True			molecular_function											owl:Class	
GO:0052354	biolink:NamedThing	obsolete catabolism by organism of carbohydrate in other organism involved in symbiotic interaction	OBSOLETE. The chemical reactions and pathways performed by an organism resulting in the breakdown of carbohydrate molecules within a second organism, where the two organisms are in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	catabolism by organism of carbohydrate in other organism during symbiotic interaction	https://github.com/geneontology/go-ontology/issues/21469				This term was obsoleted because it represents a molecular function.					True			biological_process											owl:Class	
GO:0023053	biolink:NamedThing	obsolete signal initiation by mechanical effect	OBSOLETE. The process in which a mechanical signal causes activation of a receptor.	tmpzr1t_l9r_go_relaxed.owl	signal initiation by mechanical effect					This term was made obsolete because the meaning of the term is ambiguous.	GO:0007165|GO:0071260|GO:0038023		2010-02-16T09:30:50Z		True			biological_process											owl:Class	
GO:0070190	biolink:NamedThing	obsolete inositol hexakisphosphate 1-kinase or 3-kinase activity	OBSOLETE. Catalysis of the reaction: ATP + 1D-myo-inositol hexakisphosphate = ADP + 1-diphospho-1D-myo-inositol (2,3,4,5,6)pentakisphosphate, and ATP + 1D-myo-inositol hexakisphosphate = ADP + 3-diphospho-1D-myo-inositol (1,2,4,5,6)pentakisphosphate.	tmpzr1t_l9r_go_relaxed.owl	inositol hexakisphosphate 1-kinase or 3-kinase activity					This term was made obsolete because it represents two reactions, and should be two separate terms.	GO:0052724|GO:0052723				True			molecular_function											owl:Class	
GO:0033868	biolink:NamedThing	obsolete Goodpasture-antigen-binding protein kinase activity	OBSOLETE. Catalysis of the reaction: ATP + Goodpasture antigen-binding protein = ADP + Goodpasture antigen-binding phosphoprotein.	tmpzr1t_l9r_go_relaxed.owl	STK11|Goodpasture antigen-binding protein kinase activity|GPBPK|GPBP kinase activity|ATP:Goodpasture antigen-binding protein phosphotransferase activity				EC:2.7.11.9|MetaCyc:2.7.11.9-RXN	This term was made obsolete because it represents a specific gene product.					True			molecular_function											owl:Class	
GO:0046255	biolink:NamedThing	obsolete 2,4,6-trinitrotoluene biosynthetic process	OBSOLETE. The chemical reactions and pathways resulting in the formation of 2,4,6-trinitrotoluene, 1-methyl-2,4,6-trinitrobenzene.	tmpzr1t_l9r_go_relaxed.owl	2,4,6-trinitrotoluene synthesis|2,4,6-trinitrotoluene anabolism|2,4,6-trinitrotoluene biosynthesis|2,4,6-trinitrotoluene biosynthetic process|2,4,6-trinitrotoluene formation			GO:0018974		This term was made obsolete because 2,4,6-trinitrotoluene is not synthesized by living organisms, and GO does not cover non-biological processes.					True			biological_process											owl:Class	
GO:0098740	biolink:NamedThing	obsolete multi organism cell adhesion	OBSOLETE. Cell adhesion that involves cells from multiple organisms or that is mediated by gene products from multiple organisms.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because there is no evidence that this process exists.					True			biological_process											owl:Class	
GO:0008619	biolink:NamedThing	obsolete RHEB small monomeric GTPase activity	OBSOLETE. Catalysis of the reaction: GTP + H2O = GDP + phosphate.	tmpzr1t_l9r_go_relaxed.owl	RHEB small monomeric GTPase activity			GO:0003924		This term was made obsolete because it represents a gene product.	GO:0001558|GO:0051726				True			molecular_function											owl:Class	
GO:1905158	biolink:NamedThing	obsolete regulation of Factor XII activation	OBSOLETE. Any process that modulates the frequency, rate or extent of Factor XII activation.	tmpzr1t_l9r_go_relaxed.owl	regulation of Hageman factor activation					This term was accidentally approved after TermGenie review.  It should not have been approved.		sl	2016-04-19T23:03:25Z		True			biological_process											owl:Class	
GO:0008245	biolink:NamedThing	obsolete lysosomal membrane hydrogen-transporting ATPase	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	V-ATPase|lysosomal membrane hydrogen-transporting ATPase					This term was made obsolete because more specific terms were created.	GO:0046611				True			cellular_component											owl:Class	
GO:0005603	biolink:NamedThing	obsolete complement component C2 complex	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	complement component C2 complex					This term was made obsolete because prior to cleavage, complement component C2 is a single polypeptide rather than a complex, and after cleavage the products do not remain physically associated; there is thus no known biological entity corresponding to "complement C2 complex".					True			cellular_component											owl:Class	
GO:0043901	biolink:NamedThing	obsolete negative regulation of multi-organism process	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of a multi-organism process, a process in which an organism has an effect on another organism of the same or different species.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it is an unnecessary grouping term.					True			biological_process											owl:Class	
GO:1990807	biolink:NamedThing	obsolete protein N-acetyltransferase activity	OBSOLETE. Catalysis of the transfer of an acetyl group to a nitrogen atom on the amino acid of a protein.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted at the TermGenie Gatekeeper stage.		vw	2015-07-20T15:19:23Z		True			molecular_function											owl:Class	
GO:0100023	biolink:NamedThing	obsolete regulation of meiotic nuclear division by transcription from RNA polymerase II promoter	OBSOLETE. Any transcription from RNA polymerase II promoter process that regulates meiotic nuclear division.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it represents a GO-CAM model.		cjm	2015-04-02T04:13:19Z		True			biological_process											owl:Class	
GO:0006989	biolink:NamedThing	obsolete unfolded protein response, ligation of mRNA encoding UFP-specific transcription factor by RNA ligase	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	unfolded protein response, ligation of mRNA encoding UFP-specific transcription factor by RNA ligase					This term was made obsolete because it represents a function rather than a process.	GO:0008452				True			biological_process											owl:Class	
GO:0050824	biolink:NamedThing	obsolete water binding	OBSOLETE. Binding to water (H2O).	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because water binding is non-specific.					True			molecular_function											owl:Class	
GO:0009502	biolink:NamedThing	obsolete photosynthetic electron transport chain	OBSOLETE. A series of membrane-linked oxidation-reduction reactions in which electrons are transferred from an initial electron donor through a series of intermediates to a final electron acceptor (usually oxygen).	tmpzr1t_l9r_go_relaxed.owl	photosynthetic electron transport chain					This term was made obsolete because it represents a process.	GO:0009767				True			cellular_component											owl:Class	
GO:0052434	biolink:NamedThing	obsolete modulation by organism of symbiont cell-mediated immune response	OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of any form of cell-based immune response of a symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	modulation by organism of symbiont cell-based immune response|modulation by organism of symbiont cell-mediated immune response					This term was made obsolete because it does not represent a real biological process.					True			biological_process											owl:Class	
GO:0052557	biolink:NamedThing	obsolete positive regulation by organism of symbiont immune response	OBSOLETE. Any process by which an organism activates, maintains or increases the frequency, rate or extent of the immune response of the symbiont organism; the immune response is any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	positive regulation by organism of symbiont immune response					This term was made obsolete because it does not represent a real biological process.					True			biological_process											owl:Class	
GO:0004299	biolink:NamedThing	obsolete proteasome endopeptidase activity	OBSOLETE. Catalysis of the cleavage at peptide bonds with very broad specificity.	tmpzr1t_l9r_go_relaxed.owl	proteasome|proteasome endopeptidase activity|proteasome endopeptidase complex|multicatalytic endopeptidase					This term was made obsolete because it mentions a component term in the text string.	GO:0008233|GO:0004175				True			molecular_function											owl:Class	
GO:0015993	biolink:NamedThing	obsolete molecular hydrogen transport	OBSOLETE. The directed movement of molecular hydrogen (H2) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.	tmpzr1t_l9r_go_relaxed.owl						The reason for obsoletion is that there molecular hydrogen (H2) diffuses passively through membranes (see https://www.researchgate.net/post/How_molecular_hydrogen_is_transported_through_the_cytoplasmic_membrane_of_Escherichia_coli).					True			biological_process											owl:Class	
GO:0036096	biolink:NamedThing	obsolete 3'-5'-exoribonuclease activity involved in pre-miRNA 3'-end processing	OBSOLETE. Catalysis of the sequential cleavage of mononucleotides from a free 3' terminus of an RNA molecule that contributes to forming the mature 3' end of a miRNA from a pre-miRNA.	tmpzr1t_l9r_go_relaxed.owl	3'-5'-exoribonuclease activity involved in pre-miRNA 3'-end processing|exonucleolytic trimming to generate 3' end of miRNA from pre-miRNA					This term was made obsolete because it is not real a process, and was created accidentally.		bf	2012-01-24T02:29:03Z		True			molecular_function											owl:Class	
GO:0045896	biolink:NamedThing	obsolete regulation of transcription during mitotic cell cycle	OBSOLETE. A cell cycle process that modulates the frequency, rate or extent of transcription that occurs during the mitotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl	regulation of transcription, mitotic|mitotic regulation of transcription	https://github.com/geneontology/go-ontology/issues/14896				The reason for obsoletion is that 'during' should be captured using an annotation extension.	GO:0006357|GO:0044772				True			biological_process											owl:Class	
GO:0042529	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0006802	biolink:NamedThing	obsolete catalase reaction	OBSOLETE. The processes involved in the induction or activation of catalase, an enzyme that catalyzes the conversion of H2O2 into H2O.	tmpzr1t_l9r_go_relaxed.owl	hydroperoxidase reaction|catalase reaction					This term was made obsolete because it represents a molecular function.	GO:0004096				True			biological_process											owl:Class	
GO:0015644	biolink:NamedThing	obsolete lipoprotein antitoxin	OBSOLETE. Binds to a lipoprotein toxin, which is usually derived from a microorganism, thereby neutralizing it.	tmpzr1t_l9r_go_relaxed.owl	lipoprotein antitoxin			GO:0015643		This term was made obsolete because it does not represent a function distinct from its parent term.					True			molecular_function											owl:Class	
GO:0005082	biolink:NamedThing	obsolete receptor signaling protein tyrosine phosphatase signaling protein activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	receptor signalling protein tyrosine phosphatase signalling protein activity|receptor signaling protein tyrosine phosphatase signaling protein activity					This term was made obsolete because the meaning of the term is ambiguous and it incorporates process information.	GO:0035556				True			molecular_function											owl:Class	
GO:0009487	biolink:NamedThing	obsolete glutaredoxin	OBSOLETE. A small disulfide-containing redox protein that serves as a glutathione-disulfide oxidoreductase.	tmpzr1t_l9r_go_relaxed.owl	glutaredoxin					This term was made obsolete because it represents a gene product.	GO:0015038|GO:0015036|GO:0003756				True			molecular_function											owl:Class	
GO:0085008	biolink:NamedThing	obsolete interaction with host via secreted substance released from microneme	OBSOLETE. An interaction with the host organism mediated by a substance released by the other (symbiont) organism via the microneme, a small, elongated secretory organelle that forms part of the apical complex of an apicomplexan parasite. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl						This term was deprecated because it conflated the process in which a gene product is involved with the secretion system by which it reaches its target.		jl	2010-02-10T03:03:16Z		True			biological_process											owl:Class	
GO:0075161	biolink:NamedThing	obsolete negative regulation of G-protein alpha subunit-mediated signal transduction in response to host	OBSOLETE. Any process in which the symbiont organism stops, prevents, or reduces the frequency, rate or extent of its symbiont G-protein alpha subunit-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of symbiont G-protein alpha subunit-mediated signal transduction in response to host					This term was obsoleted because there is no evidence that this process exists.					True			biological_process											owl:Class	
GO:0035956	biolink:NamedThing	obsolete regulation of starch catabolic process by regulation of transcription from RNA polymerase II promoter	OBSOLETE. Any process that modulates the frequency, rate or extent of the breakdown of starch, by modulating the frequency, rate or extent of transcription from an RNA polymerase II promoter.	tmpzr1t_l9r_go_relaxed.owl	regulation of starch degradation by regulation of transcription from Pol II promoter|regulation of starch breakdown by regulation of transcription from RNA polymerase II promoter|regulation of starch catabolic process by regulation of transcription from Pol II promoter|regulation of starch catabolism by regulation of transcription from Pol II promoter|regulation of starch degradation by regulation of transcription from RNA polymerase II promoter|regulation of starch breakdown by regulation of transcription from Pol II promoter|regulation of starch catabolism by regulation of transcription from RNA polymerase II promoter					This term was obsoleted because it represents a GO-CAM model.		bf			True			biological_process											owl:Class	
GO:0003822	biolink:NamedThing	obsolete MHC-interacting protein	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	MHC-interacting protein					This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0008229	biolink:NamedThing	obsolete opsonin activity	OBSOLETE. Binds to microorganisms or other particulate material (for example, foreign erythrocytes) to increase the susceptibility of the latter to phagocytosis.	tmpzr1t_l9r_go_relaxed.owl	opsonin activity					This term was made obsolete because it represents a class of gene products.	GO:0003823				True			molecular_function											owl:Class	
GO:0001950	biolink:NamedThing	obsolete plasma membrane enriched fraction	OBSOLETE. The fraction of cells, prepared by disruptive biochemical methods, that is enriched for plasma membranes.	tmpzr1t_l9r_go_relaxed.owl	PME fraction|plasma membrane enriched fraction					This term was made obsolete because it refers to a cell fractionation experimental result and not a bona fide cellular component.	GO:0005886				True			cellular_component											owl:Class	
GO:0031275	biolink:NamedThing	obsolete regulation of lateral pseudopodium assembly	OBSOLETE. Any process that modulates the frequency, rate or extent of the assembly of pseudopodia from the lateral side of the cell.	tmpzr1t_l9r_go_relaxed.owl	regulation of lateral pseudopodium formation	https://github.com/geneontology/go-ontology/issues/21738				The regulation of lateral pseudopodium assembly terms were not used consistently. The negative regulation term has been replaced by GO:0120320 lateral pseudopodium retraction.					True			biological_process											owl:Class	
GO:0085009	biolink:NamedThing	obsolete interaction with host mediated by symbiont secreted substance released from Maurer's cleft	OBSOLETE. An interaction with the host organism mediated by a substance released by the other (symbiont) organism via Maurer's cleft. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	interaction with host mediated by symbiont secreted substance released from Maurers cleft					This term was obsoleted because it conflated the process in which a gene product is involved with the secretion system by which it reaches its target.		jl	2010-02-10T03:08:39Z		True			biological_process											owl:Class	
GO:0010545	biolink:NamedThing	obsolete Hsp90 protein regulator activity	OBSOLETE. Binds to and modulates the activity of the molecular chaperone Hsp90.	tmpzr1t_l9r_go_relaxed.owl	Hsp90 protein regulator activity			GO:0051879		This term was made obsolete because it refers to a non-existent molecular function term, 'Hsp90 protein activity'.	GO:0051082|GO:0051787|GO:0006457				True			molecular_function											owl:Class	
GO:0052435	biolink:NamedThing	obsolete modulation by host of defense-related symbiont MAP kinase-mediated signal transduction pathway	OBSOLETE. Any process in which an organism modulates the frequency, rate or extent of symbiont MAP kinase-mediated signal transduction pathways during the symbiont defense response. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	modulation of defense-related symbiont mitogen activated protein kinase-mediated signal transduction pathway by organism|modulation of defense-related symbiont MAPK-mediated signal transduction pathway by organism					The reason for obsoletion is that there is no evidence that the host can modulate or regulate a symbiont's signal transduction pathway.					True			biological_process											owl:Class	
GO:0035952	biolink:NamedThing	obsolete negative regulation of oligopeptide transport by negative regulation of transcription from RNA polymerase II promoter	OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of oligopeptide transport by stopping, preventing or reducing the frequency, rate or extent of transcription from an RNA polymerase II promoter.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of oligopeptide transport by inhibition of transcription from RNA polymerase II promoter|negative regulation of oligopeptide transport by down regulation of transcription from RNA polymerase II promoter|negative regulation of oligopeptide transport by down-regulation of transcription from RNA polymerase II promoter|negative regulation of oligopeptide transport by negative regulation of transcription from Pol II promoter|negative regulation of oligopeptide transport by downregulation of transcription from RNA polymerase II promoter					This term was obsoleted because it represents a GO-CAM model.		bf			True			biological_process											owl:Class	
GO:0001190	biolink:NamedThing	obsolete transcriptional activator activity, RNA polymerase II transcription factor binding	OBSOLETE. Binding to an RNA polymerase II transcription factor, which may be a single protein or a complex, in order to increase the frequency, rate or extent of transcription from an RNA polymerase II promoter. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well.	tmpzr1t_l9r_go_relaxed.owl	RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription|RNA polymerase II transcription factor binding transcription activator activity	https://github.com/geneontology/go-ontology/issues/16053				The reason for obsoletion is that this concept is partly covered by other concepts in the ontology and usage has been inconsistent.	GO:0001228|GO:0061629	krc	2011-08-25T02:07:14Z		True			molecular_function											owl:Class	
GO:0055126	biolink:NamedThing	obsolete Nup82 complex	OBSOLETE. A protein complex that forms part of the nuclear pore complex. It forms a subcomplex with Nup159p and Nsp1p, interacts with Nup116p, and is required for proper localization of Nup116p. In Saccharomyces cerevisiae this complex contains Nup82p, Nsp1p, Nup159p, Nup116p, and Gle2p.	tmpzr1t_l9r_go_relaxed.owl	Nup82 complex						GO:0044612	jid	2009-10-12T08:35:34Z		True			cellular_component											owl:Class	
GO:0008529	biolink:NamedThing	obsolete endogenous peptide receptor activity	OBSOLETE. Combining with an intracellular peptide to initiate a change in cell activity.	tmpzr1t_l9r_go_relaxed.owl	endogenous peptide receptor activity					This term was made obsolete because it contains both component and function information.	GO:0001653|GO:0005622				True			molecular_function											owl:Class	
GO:0018325	biolink:NamedThing	obsolete enzyme active site formation via S-phospho-L-cysteine	OBSOLETE. The transient phosphorylation of peptidyl-cysteine to form S-phospho-L-cysteine.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/15594			RESID:AA0034	This term was obsoleted because it represents a reaction intermediate, not a biological process, see PMID:3142516 and PMID:22927394.					True			biological_process											owl:Class	
GO:0048192	biolink:NamedThing	obsolete peptide antigen stabilization activity	OBSOLETE. Strengthening of a bond with a peptide antigen; a fragment of a foreign protein derived by proteolysis within the cell.	tmpzr1t_l9r_go_relaxed.owl	peptide antigen stabilization activity			GO:0050823		This term was made obsolete because it represents a biological process.					True			molecular_function											owl:Class	
GO:0052427	biolink:NamedThing	obsolete modulation by host of symbiont peptidase activity	OBSOLETE. The process in which an organism effects a change in symbiont peptidase activity, the catalysis of the hydrolysis of peptide bonds in a protein. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	modulation by host of symbiont protease activity	https://github.com/geneontology/go-ontology/issues/21740				This term was obsoleted because it represents a molecular function.					True			biological_process											owl:Class	
GO:0016564	biolink:NamedThing	obsolete transcription repressor activity	OBSOLETE. Any transcription regulator activity that prevents or downregulates transcription.	tmpzr1t_l9r_go_relaxed.owl	transcription repressor activity|negative transcriptional regulator activity|transcriptional repressor activity					This term was obsoleted because it is essentially identical to a Process term (specifically the Biological Process term which has been selected as a term to consider for reannotation), i.e. it is defined only in terms of the process it acts in and it does NOT convey any information about the molecular nature of the function or whether the function is based on binding DNA, on interacting with other proteins, or some other mechanism. To transfer all annotations without review, the BP term indicated is considered to be equivalent and thus the only appropriate destination for all annotations. To reannotate to a MF term, you will probably need to revisit the original literature or other primary data because this "MF" term was not defined in terms of mechanism of action and there are multiple possibilities in the revised MF structure. In reannotation, please also consider descendent terms of the suggested MF terms as a more specific term may be more appropriate than the MF terms indicated. Please be aware that you may wish to request a new term if the mechanism of action of this gene product is not yet represented or if you are annotating for an RNAP different than one for which there is a specific suggested term. Also note that if there is no information about how the gene product acts, it may be appropriate to annotate to the root term for molecular_function.	GO:0001227				True			molecular_function											owl:Class	
GO:0001169	biolink:NamedThing	obsolete transcription factor activity, RNA polymerase I CORE element sequence-specific binding	OBSOLETE. Binding to CORE element, a regulatory region composed of the transcription start site and binding sites for transcription factors of the RNA polymerase I transcription machinery in order to modulate transcription by RNA polymerase I.	tmpzr1t_l9r_go_relaxed.owl	RNA polymerase I core promoter sequence-specific DNA binding transcription factor|RNA polymerase I CORE element sequence-specific DNA binding transcription factor activity	https://github.com/geneontology/go-ontology/issues/15787				This term was obsoleted because it represents two separate functions. The corresponding 'binding' term should be used in combination with a transcription regulator activity child.		krc	2011-02-03T04:10:42Z		True			molecular_function											owl:Class	
GO:0004868	biolink:NamedThing	obsolete serpin	OBSOLETE. A superfamily of proteins, many of which inhibit serine proteinases and exhibit a high degree of homology with classical serine proteinase inhibitors such as alpha1-antitrypsin or antithrombin.	tmpzr1t_l9r_go_relaxed.owl	serpin					This term was made obsolete because it represents a class of gene products.	GO:0004867				True			molecular_function											owl:Class	
GO:0014918	biolink:NamedThing	obsolete positive regulation of natriuresis by pressure natriuresis	OBSOLETE. The process in which pressure natriuresis increases rate of natriuresis.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of natriuresis by pressure natriuresis			GO:0035819		This term was made obsolete because its definition was inaccurate.					True			biological_process											owl:Class	
GO:1905107	biolink:NamedThing	obsolete cellular response to Dizocilpine	OBSOLETE. Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a Dizocilpine stimulus.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted at the TermGenie Gatekeeper stage.		sl	2016-04-04T20:27:01Z		True			biological_process											owl:Class	
RO:0002299	biolink:NamedThing	results in maturation of		tmpzr1t_l9r_go_relaxed.owl					RO:0002299									external									results_in_maturation_of			
GO:0106187	biolink:NamedThing	obsolete translocase activity acting on hydrons linked to oxidoreductase reactions	OBSOLETE. Catalysis of the translocation of hydrons linked to an oxidoreduction reaction.	tmpzr1t_l9r_go_relaxed.owl					EC:7.1.1.-	This term was made obsolete because the concept of using the non-4 digit EC classes as parent terms for the transporter banch of the onotolgy was consided confusing.		hjd	2019-05-07T18:04:40Z		True			molecular_function											owl:Class	
GO:0019845	biolink:NamedThing	obsolete exotoxin activity	OBSOLETE. The function of a toxin formed by a microorganism and secreted into the surrounding medium.	tmpzr1t_l9r_go_relaxed.owl	exotoxin activity					This term was made obsolete because it represents a class of gene products.	GO:0090729|GO:0005576				True			molecular_function											owl:Class	
GO:0100035	biolink:NamedThing	obsolete negative regulation of transmembrane transport by transcription from RNA polymerase II promoter	OBSOLETE. Any transcription from RNA polymerase II promoter process that negatively regulates transmembrane transport.	tmpzr1t_l9r_go_relaxed.owl						The term was obsoleted because it is better represented by a GO-CAM model.		cjm	2015-04-02T04:13:19Z		True			biological_process											owl:Class	
GO:0015447	biolink:NamedThing	obsolete type II protein secretor activity	OBSOLETE. This term was not defined before being made obsolete.	tmpzr1t_l9r_go_relaxed.owl	type II protein secretor activity					This term was made obsolete because it does not accurately reflect the function of the proteins involved.					True			molecular_function											owl:Class	
GO:1903693	biolink:NamedThing	obsolete regulation of mitotic G1 cell cycle arrest in response to nitrogen starvation	OBSOLETE. Any process that modulates the frequency, rate or extent of mitotic G1 cell cycle arrest in response to nitrogen starvation.	tmpzr1t_l9r_go_relaxed.owl	regulation of G1 mitotic cell cycle arrest in response to nitrogen starvation	https://github.com/geneontology/go-ontology/issues/20989				This term was obsoleted because it does not represent a specific process.		al	2014-12-02T18:16:03Z		True			biological_process											owl:Class	
GO:0023017	biolink:NamedThing	obsolete signal transmission via diffusible molecule	OBSOLETE. The process in which a signal is conveyed via a diffusible molecule.	tmpzr1t_l9r_go_relaxed.owl	signal transmission via diffusible molecule|signaling via diffusible mediator					This term was made obsolete because the meaning of the term is ambiguous.	GO:0007267		2010-02-16T09:30:50Z		True			biological_process											owl:Class	
GO:1900448	biolink:NamedThing	obsolete regulation of pyrimidine nucleotide biosynthetic process by positive regulation of transcription from RNA polymerase II promoter	OBSOLETE. Any process that modulates the frequency, rate or extent of pyrimidine nucleotide biosynthesis by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it represents a GO-CAM model.		jh	2012-04-27T02:57:38Z		True			biological_process											owl:Class	
GO:0015003	biolink:NamedThing	obsolete copper electron carrier	OBSOLETE. A copper-containing entity that serves as an electron acceptor and electron donor in an electron transport system.	tmpzr1t_l9r_go_relaxed.owl	copper electron carrier			GO:0009055		This term was made obsolete because it refers to a class of gene products.					True			molecular_function											owl:Class	
GO:0015617	biolink:NamedThing	obsolete pilin/fimbrilin exporter activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	pilin/fimbrilin exporter activity					This term was made obsolete because it represents a gene product.	GO:0015462				True			molecular_function											owl:Class	
GO:0000189	biolink:NamedThing	obsolete MAPK import into nucleus	OBSOLETE. The directed movement of a MAP kinase to the nucleus upon activation.	tmpzr1t_l9r_go_relaxed.owl	nuclear translocation of MAPK					The reason for obsoletion is that all proteins are imported into the nucleus via the same mechanism, so the import of individual proteins should be captured with extensions or by GO-CAM models.	GO:0006606				True			biological_process											owl:Class	
GO:0009485	biolink:NamedThing	obsolete cbb3-type cytochrome c oxidase	OBSOLETE. Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: 4 ferrocytochrome c + O2 = 4 ferricytochrome c + 2 H2O.	tmpzr1t_l9r_go_relaxed.owl	cbb3-type cytochrome c oxidase			GO:0004129		This term was made obsolete because it describes a class of gene products rather than a molecular function.					True			molecular_function											owl:Class	
GO:0018314	biolink:NamedThing	obsolete protein-pyrroloquinoline-quinone linkage	OBSOLETE. The covalent cross-linking of pyrroloquinoline-quinone to peptidyl-glutamic acid and peptidyl-tyrosine.	tmpzr1t_l9r_go_relaxed.owl	protein-pyrroloquinoline-quinone linkage			GO:0006464							True			biological_process											owl:Class	
GO:0000726	biolink:NamedThing	obsolete non-recombinational repair	OBSOLETE. A DNA repair process in which that does not require the exchange of genetic material between the broken DNA molecule and a homologous DNA region.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/18901				This term was obsoleted because it was defined negatively, and it represents an unnecessary grouping class.					True			biological_process											owl:Class	
RO:0002220	biolink:NamedThing	adjacent to		tmpzr1t_l9r_go_relaxed.owl					RO:0002220									external									adjacent_to			
GO:0044133	biolink:NamedThing	obsolete growth of symbiont on or near host	OBSOLETE. The increase in size or mass of a symbiont within the cells or tissues of its host organism.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it represented both a process and a location.		jl	2009-08-04T03:36:49Z		True			biological_process											owl:Class	
GO:0052240	biolink:NamedThing	obsolete positive chemotaxis in other organism involved in symbiotic interaction	OBSOLETE. The directed movement of a motile cell or organism towards a higher concentration of a specific chemical within a second organism, where the two organisms are in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	positive chemotaxis in other organism during symbiotic interaction|positive chemotaxis within other organism during symbiotic interaction	https://github.com/geneontology/go-ontology/issues/18819				This term was obsoleted because it represents both a process and a location.					True			biological_process											owl:Class	
GO:0016304	biolink:NamedThing	obsolete phosphatidylinositol 3-kinase activity, class I	OBSOLETE. A heterodimeric phosphoinositide 3-kinase which can phosphorylate phosphatidylinositol, phosphatidylinositol-4-phosphate or phosphatidylinositol-4,5-bisphosphate. Also possesses intrinsic protein kinase activity.	tmpzr1t_l9r_go_relaxed.owl	phosphatidylinositol 3-kinase activity, class I					This term was made obsolete because it represents a class of gene products.	GO:0046934|GO:0016303|GO:0035005				True			molecular_function											owl:Class	
GO:1900462	biolink:NamedThing	obsolete negative regulation of pseudohyphal growth by negative regulation of transcription from RNA polymerase II promoter	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of pseudohyphal growth by stopping, preventing, or reducing the frequency, rate or extent of transcription from an RNA polymerase II promoter.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it represents a GO-CAM model.		dgf	2012-05-01T07:01:54Z		True			biological_process											owl:Class	
GO:1990494	biolink:NamedThing	obsolete regulation of mitotic cytokinesis, actomyosin contractile ring assembly	OBSOLETE. Any process that modulates the frequency, rate or extent of mitotic cytokinesis, actomyosin contractile ring assembly.	tmpzr1t_l9r_go_relaxed.owl	regulation of mitotic cytokinesis, actomyosin contractile ring assembly					This term was obsoleted at the TermGenie Gatekeeper stage.		al	2014-09-25T09:04:55Z		True			biological_process											owl:Class	
GO:0019675	biolink:NamedThing	obsolete NAD phosphorylation and dephosphorylation	OBSOLETE. The addition or removal of a phosphate group from nicotinamide adenine dinucleotide (NAD), a coenzyme present in most living cells and derived from the B vitamin nicotinic acid.	tmpzr1t_l9r_go_relaxed.owl	nicotinamide adenine dinucleotide phosphorylation and dephosphorylation|NAD phosphorylation and dephosphorylation					This term was made obsolete because it represents a process, NAD dephosphorylation, that does not exist.	GO:0019674|GO:0006739				True			biological_process											owl:Class	
GO:0016969	biolink:NamedThing	obsolete hemerythrin	OBSOLETE. An oxygen carrier found in a few groups of invertebrates, e.g. sipunculid worms, certain molluscs, and crustaceans.	tmpzr1t_l9r_go_relaxed.owl	hemerythrin			GO:0005344		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0023040	biolink:NamedThing	obsolete signaling via ionic flux	OBSOLETE. The process in which information is sent from one location to another, within a living organism or between living organisms, via ionic flux.	tmpzr1t_l9r_go_relaxed.owl	signaling via ionic flux|signalling via ionic flux					This term was made obsolete because the meaning of the term is ambiguous.	GO:0023052		2010-02-16T09:30:50Z		True			biological_process											owl:Class	
GO:0001186	biolink:NamedThing	obsolete RNA polymerase I transcription regulator recruiting activity	OBSOLETE. The function of binding to an RNA polymerase I (RNAP I) transcription regulator and recruiting it to the general transcription machinery complex in order to modulate transcription initiation.	tmpzr1t_l9r_go_relaxed.owl	RNA polymerase I transcription factor recruiting activity|transcription factor activity, RNA polymerase I transcription factor recruiting|RNA polymerase I transcription factor recruiting transcription factor activity	https://github.com/geneontology/go-ontology/issues/18561		GO:0003712		The reason for obsoletion is that this function is redundant with other terms, most often 'transcription co-regulator activity; GO:0003712'.		krc	2011-08-24T04:00:18Z		True			molecular_function											owl:Class	
GO:0016806	biolink:NamedThing	obsolete dipeptidyl-peptidase and tripeptidyl-peptidase activity	OBSOLETE. Catalysis of the hydrolysis of N-terminal di- or tripeptides from a polypeptide chain.	tmpzr1t_l9r_go_relaxed.owl	dipeptidyl-peptidase and tripeptidyl-peptidase activity				EC:3.4.14.-	This term was made obsolete because it represents two activities.					True			molecular_function											owl:Class	
GO:0035947	biolink:NamedThing	obsolete regulation of gluconeogenesis by regulation of transcription from RNA polymerase II promoter	OBSOLETE. Any process that modulates the frequency, rate or extent of gluconeogenesis, by regulation of transcription from an RNA polymerase II promoter.	tmpzr1t_l9r_go_relaxed.owl	regulation of glucose biosynthetic process by regulation of transcription from Pol II promoter|regulation of glucose biosynthesis by regulation of transcription from RNA polymerase II promoter|regulation of gluconeogenesis by regulation of transcription from Pol II promoter|regulation of glucose biosynthesis by regulation of transcription from Pol II promoter|regulation of glucose biosynthetic process by regulation of transcription from RNA polymerase II promoter					This term was obsoleted because it represents a GO-CAM model.		bf			True			biological_process											owl:Class	
GO:0070035	biolink:NamedThing	obsolete purine NTP-dependent helicase activity	OBSOLETE. Catalysis of the reaction: purine NTP + H2O = purine NDP + phosphate, to drive the unwinding of a DNA or RNA helix.	tmpzr1t_l9r_go_relaxed.owl						The reason for obsoletion is that helicases only and always use ATP (although under very specific experimental conditions GTP can perhaps be used; this is not the case in vivo), therefore this term was an unnecessary grouping term.					True			molecular_function											owl:Class	
GO:0042769	biolink:NamedThing	obsolete DNA damage response, detection of DNA damage	OBSOLETE. The series of events required to receive a stimulus indicating DNA damage has occurred and convert it to a molecular signal.	tmpzr1t_l9r_go_relaxed.owl	DNA damage response, perception of DNA damage|detection of DNA damage during DNA damage response	https://github.com/geneontology/go-ontology/issues/19051				This term has been obsoleted because it represents a molecular function.	GO:0006281|GO:0140664|GO:0140612				True			biological_process											owl:Class	
GO:0036045	biolink:NamedThing	obsolete peptidyl-lysine malonylation	OBSOLETE. The addition of a malonyl group (CO-CH2-CO) to peptidyl-lysine to form N6-malonyl-L-lysine.	tmpzr1t_l9r_go_relaxed.owl	lysine malonylation|peptidyl-lysine malonylation			GO:0044392		This term was made obsolete because it accidentally reused an exisiting id. See replacement term GO:0044392.		bf	2011-12-12T09:31:42Z		True			biological_process											owl:Class	
term_tracker_item	biolink:NamedThing	term tracker item		tmpzr1t_l9r_go_relaxed.owl					IAO:0000233									external	True	True							term_tracker_item		owl:AnnotationProperty	
GO:0051416	biolink:NamedThing	obsolete myotilin binding	OBSOLETE. Binding to myotilin, a structural component of the Z-discs in human skeletal and cardiac muscle. Its C-terminus contains two immunoglobulin-like domains and the unique N-terminal half has a serine-rich region, with numerous potential phosphorylation sites, and a stretch of hydrophobic amino acids. Myotilin forms homodimers and binds to alpha-actinin, F-actin, and filamin C.	tmpzr1t_l9r_go_relaxed.owl	myotilin binding			GO:0008092		This term was made obsolete because it represents binding to an individual protein.					True			molecular_function											owl:Class	
GO:0005376	biolink:NamedThing	obsolete plasma membrane copper transporter	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	plasma membrane copper transporter					This term was made obsolete because it contains both component and function information.	GO:0005375|GO:0005886				True			molecular_function											owl:Class	
GO:0000504	biolink:NamedThing	obsolete proteasome regulatory particle (sensu Bacteria)	OBSOLETE. A multisubunit complex that recognizes and unfolds ubiquitinated proteins, and translocates them to the core complex in an ATP dependent manner. As in, but not restricted to, the taxon Bacteria (Bacteria, ncbi_taxonomy_id:2).	tmpzr1t_l9r_go_relaxed.owl	26S proteasome|proteasome regulatory particle (sensu Bacteria)					This term was made obsolete because there is no ubiquitin in bacteria and they do not have proteasome regulatory particles. Instead they have proteasome-activating nucleotidase.					True			cellular_component											owl:Class	
GO:0023010	biolink:NamedThing	obsolete regulation of initiation of T cell receptor signaling	OBSOLETE. Any process that modulates the frequency, rate or extent of the initiation of T cell receptor signaling.	tmpzr1t_l9r_go_relaxed.owl	regulation of initiation of T cell receptor signaling|regulation of initiation of T cell receptor signalling					This term was made obsolete because the meaning of the term is ambiguous.	GO:0050856		2010-02-16T09:30:50Z		True			biological_process											owl:Class	
GO:1902353	biolink:NamedThing	obsolete positive regulation of induction of conjugation with cellular fusion by negative regulation of transcription from RNA polymerase II promoter by pheromones	OBSOLETE. A negative regulation of transcription from RNA polymerase II promoter by pheromones that results in positive regulation of induction of conjugation with cellular fusion.	tmpzr1t_l9r_go_relaxed.owl	up regulation of induction of conjugation with cellular fusion by negative regulation of transcription from RNA polymerase II promoter by pheromones|up-regulation of induction of conjugation with cellular fusion by negative regulation of transcription from RNA polymerase II promoter by pheromones|upregulation of induction of conjugation with cellular fusion by negative regulation of transcription from RNA polymerase II promoter by pheromones					This term was obsoleted because it represents a GO-CAM model.		bf	2013-08-14T09:45:21Z		True			biological_process											owl:Class	
GO:1903474	biolink:NamedThing	obsolete anchoring of the mitotic actomyosin contractile ring to the plasma membrane	OBSOLETE. A process that maintains the mitotic actinomyosin contractile ring at the plasma membrane.	tmpzr1t_l9r_go_relaxed.owl	cytokinetic ring anchoring involved in mitotic cell cycle|maintenance of contractile ring localization involved in cell cycle cytokinesis involved in mitotic cell cycle|maintenance of contractile ring localisation involved in cell cycle cytokinesis involved in mitotic cell cycle|maintenance of contractile ring localization involved in cytokinesis during cell cycle involved in mitotic cell cycle					The reason for obsoletion is that this term represents a GO-CAM model.		vw	2014-09-23T14:12:48Z		True			biological_process											owl:Class	
GO:0030051	biolink:NamedThing	obsolete FK506-sensitive peptidyl-prolyl cis-trans isomerase	OBSOLETE. Interacts selectively with the immunosuppressant FK506, and possesses peptidyl-prolyl isomerase activity (catalysis of the reaction: peptidoproline (omega=180) = peptidylproline (omega=0)).	tmpzr1t_l9r_go_relaxed.owl	FK506-sensitive peptidyl-prolyl cis-trans isomerase|FK506 binding protein|FKBP					This term was made obsolete because it represents a gene product and not a function.	GO:0005528|GO:0003755				True			molecular_function											owl:Class	
GO:0019848	biolink:NamedThing	obsolete conotoxin activity	OBSOLETE. Acts to inhibit neural function in another organism by inhibiting voltage-gated calcium ion channels and neurotransmitter release. This function is thought to be specific to the venom of two marine snail species.	tmpzr1t_l9r_go_relaxed.owl	conotoxin activity					This term was made obsolete because it represents a gene product.	GO:0046929|GO:0019855				True			molecular_function											owl:Class	
GO:0046227	biolink:NamedThing	obsolete 2,4,5-trichlorophenoxyacetic acid biosynthetic process	OBSOLETE. The chemical reactions and pathways resulting in the formation of 2,4,5-trichlorophenoxyacetic acid, a chlorinated aromatic compound widely used as a herbicide.	tmpzr1t_l9r_go_relaxed.owl	2,4,5-trichlorophenoxyacetic acid anabolism|2,4,5-trichlorophenoxyacetic acid biosynthesis|2,4,5-trichlorophenoxyacetic acid formation|2,4,5-trichlorophenoxyacetic acid biosynthetic process|2,4,5-trichlorophenoxyacetic acid synthesis			GO:0018980		This term was made obsolete because 2,4,5-trichlorophenoxyacetic acid is not synthesized by living organisms and GO does not cover non-biological processes.					True			biological_process											owl:Class	
GO:0045192	biolink:NamedThing	obsolete low-density lipoprotein catabolic process	OBSOLETE. The chemical reactions and pathways resulting in the breakdown of low-density lipoproteins, also known as beta lipoproteins, one of the classes of lipoproteins found in the bloodstream of animals, acting as a carrier for cholesterol and fats.	tmpzr1t_l9r_go_relaxed.owl	low-density lipoprotein catabolic process|LDL catabolic process|low-density lipoprotein degradation|low-density lipoprotein catabolism|LDL catabolism|low-density lipoprotein breakdown					This term was made obsolete because low-density lipoprotein is a macromolecular complex, not a single class of molecule; its degradation involves the dissociation of non-covalently attached constituents as well as some breaking and reforming of covalent bonds.					True			biological_process											owl:Class	
GO:1990376	biolink:NamedThing	obsolete negative regulation of G1/S transition of mitotic cell cycle by positive regulation of transcription from RNA polymerase II promoter in response to nitrogen starvation	OBSOLETE. A positive regulation of transcription from RNA polymerase II promoter in response to nitrogen starvation that results in negative regulation of mitotic G1/S transition.	tmpzr1t_l9r_go_relaxed.owl						This term was made obsolete because it would not be used for annotation.		al	2014-05-07T08:51:19Z		True			biological_process											owl:Class	
GO:0085025	biolink:NamedThing	obsolete modification by symbiont of host morphology or physiology via protein secreted by Tat complex	OBSOLETE. The process in which an organism (symbiont) effects a change in the structure or function of its host organism, mediated by a substance secreted by the Tat complex in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	modification by symbiont of host morphology or physiology via protein secreted by the Tat secretion system					This term was obsoleted because it conflated the process in which a gene product is involved with the secretion system by which it reaches its target.		jl	2010-07-09T03:47:01Z		True			biological_process											owl:Class	
GO:0018587	biolink:NamedThing	obsolete limonene 8-monooxygenase activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	limonene 8-monooxygenase activity			GO:0019113		This term was made obsolete because it was derived from a UM-BBD enzyme entry that has been deleted, and no other information can be found to suggest that it is a naturally occurring activity.					True			molecular_function											owl:Class	
GO:0016458	biolink:NamedThing	obsolete gene silencing	OBSOLETE. Any process carried out at the cellular level that results in either long-term transcriptional repression via action on chromatin structure or RNA mediated, post-transcriptional repression of gene expression.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/22202			Wikipedia:Gene_silencing	This term was obsoleted because its definition was too broad, and not distinct from 'GO:0045814 negative regulation of gene expression, epigenetic'.	GO:0010629|GO:0031507				True			biological_process											owl:Class	
GO:0019575	biolink:NamedThing	obsolete sucrose catabolic process, using beta-fructofuranosidase	OBSOLETE. The chemical reactions and pathways resulting in the breakdown of sucrose, catalyzed by the enzyme beta-fructofuranosidase (EC:3.2.1.26).	tmpzr1t_l9r_go_relaxed.owl	sucrose catabolism, using beta-fructofuranosidase|sucrose degradation, using beta-fructofuranosidase|sucrose catabolic process, using beta-fructofuranosidase|sucrose breakdown, using beta-fructofuranosidase				MetaCyc:SUCUTIL-PWY	This term was made obsolete because beta-fructofuranosidase (also known as invertase) catalyzes the first step in multiple routes of sucrose catabolism.	GO:0004564|GO:0036008				True			biological_process											owl:Class	
GO:0052188	biolink:NamedThing	obsolete modification of cellular component in other organism involved in symbiotic interaction	OBSOLETE. The process in which an organism effects a change in the structure or function of a cellular component in a second organism, where the two organisms are in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	modification of cellular component in other organism during symbiotic interaction					This term was obsoleted because it represents an unnecessary grouping class.					True			biological_process											owl:Class	
GO:1905501	biolink:NamedThing	obsolete heteroreceptor complex disassembly	OBSOLETE. The disaggregation of a heteroreceptor complex into its constituent components.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted at the TermGenie Gatekeeper stage.		pad	2016-09-27T10:50:04Z		True			biological_process											owl:Class	
GO:0106191	biolink:NamedThing	obsolete translocase activity acting on inogranic cations linked to oxidoreductase reactions	OBSOLETE. Catalysis of the translocation of inorganic cations linked to oxidoreductase reactions.	tmpzr1t_l9r_go_relaxed.owl					EC:7.2.1.-	This term was made obsolete because the concept of using the non-4 digit EC classes as parent terms for the transporter banch of the onotolgy was consided confusing.		hjd	2019-05-08T16:50:07Z		True			molecular_function											owl:Class	
GO:0001086	biolink:NamedThing	obsolete transcription factor activity, TFIIA-class binding	OBSOLETE. Binding to a basal RNA polymerase II transcription factor of the TFIIA class in order to modulate transcription. The transcription factor may or may not also interact selectively with DNA as well.	tmpzr1t_l9r_go_relaxed.owl	TFIIA-class binding transcription factor activity					This term was obsoleted because it represents two separate functions. The corresponding 'binding' term should be used in combination with a transcription regulator activity child.	GO:0001092	krc	2010-10-28T02:14:59Z		True			molecular_function											owl:Class	
GO:0090485	biolink:NamedThing	obsolete chromosome number maintenance	OBSOLETE. The maintenance of the standard number of chromosomes in a cell.	tmpzr1t_l9r_go_relaxed.owl	haploidization|diploidization					The reason for obsoletion is that this term represents a phenotype, and could be captured by other terms such as GO:0007059 chromosome segregation or GO:1903467 negative regulation of mitotic DNA replication initiation.	GO:1903467|GO:0007059	tb	2012-10-05T11:21:45Z		True			biological_process											owl:Class	
GO:0016353	biolink:NamedThing	obsolete carbamate susceptibility/resistance	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	carbamate susceptibility/resistance			GO:0046681		This term was made obsolete because 'susceptibility/resistance' implies a phenotype rather than a biological process.					True			biological_process											owl:Class	
GO:0031614	biolink:NamedThing	obsolete ER proteasome regulatory particle, lid subcomplex	OBSOLETE. The subunits that form the peripheral lid of the regulatory particle of a proteasome located in the endoplasmic reticulum of a cell.	tmpzr1t_l9r_go_relaxed.owl						This term was made obsolete because there is no evidence in the literature of its existence.					True			cellular_component											owl:Class	
GO:0005928	biolink:NamedThing	obsolete apical hemi-adherens junction	OBSOLETE. A cell-substrate adherens junction found in the apical region of a cell, such as those found in cuticle-secreting epithelia, which connect the apical membrane to the cuticle.	tmpzr1t_l9r_go_relaxed.owl	apical cell-substrate adherens junction|apical dense plaque					The reason for obsoletion is that this term has not been used for GO annotation at all since 2001 when it was created, it has no children, it is not a part of any subset/slim.					True			cellular_component											owl:Class	
GO:0097607	biolink:NamedThing	obsolete negative regulation of nuclear envelope permeability	OBSOLETE. Any process that decreases the frequency, rate or extent of the passage or uptake of molecules by the nuclear envelope.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of nuclear membrane permeability					The reason for obsoletion is that the nuclear envelope is quite permeable, so there is no cellular process to regulate it.		pr	2014-05-14T15:43:47Z		True			biological_process											owl:Class	
GO:0023005	biolink:NamedThing	obsolete signal initiation by neurotransmitter	OBSOLETE. The process in which a neurotransmitter signal causes activation of a receptor.	tmpzr1t_l9r_go_relaxed.owl	signal initiation by neurotransmitter					This term was made obsolete because the meaning of the term is ambiguous.	GO:0007165|GO:0030594		2010-02-16T09:30:50Z		True			biological_process											owl:Class	
RO:0002353	biolink:NamedThing	output of		tmpzr1t_l9r_go_relaxed.owl					RO:0002353									external									output_of			
GO:1900403	biolink:NamedThing	obsolete negative regulation of cellular amino acid biosynthetic process by negative regulation of transcription from RNA polymerase II promoter	OBSOLETE. A negative regulation of transcription from RNA polymerase II promoter that results in negative regulation of cellular amino acid biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of amino acid biosynthetic process by negative regulation of transcription from RNA polymerase II promoter|negative regulation of cellular amino acid synthesis by negative regulation of transcription from RNA polymerase II promoter|negative regulation of cellular amino acid anabolism by negative regulation of transcription from RNA polymerase II promoter|negative regulation of cellular amino acid biosynthesis by negative regulation of transcription from RNA polymerase II promoter|negative regulation of cellular amino acid formation by negative regulation of transcription from RNA polymerase II promoter					This term was obsoleted because it represents a GO-CAM model.		mah	2012-04-20T02:45:42Z		True			biological_process											owl:Class	
GO:0009771	biolink:NamedThing	obsolete primary charge separation in photosystem II	OBSOLETE. Energized reaction-center P680 chlorophylls on photosystem II donate an electron to a loosely bound acceptor molecule, the quinone Q, on the stromal surface of the thylakoid membrane. The result is charge separation; a negative charge on the stromal side of the thylakoid membrane and a positive charge on the luminal side.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it represents a mechanism, and is outside the scope of GO.					True			biological_process											owl:Class	
GO:0052495	biolink:NamedThing	obsolete occlusion by organism of vascular system in other organism involved in symbiotic interaction	OBSOLETE. The process in which an organism reduces the flow of fluid within its second organism's vascular system, the vessels and tissue that carry or circulate fluids, such as blood, lymph or sap, through the body of an animal or plant, where the two organisms are in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	occlusion by organism of vascular system in other organism during symbiotic interaction					This term was obsoleted because it represents an unnecessary grouping class.					True			biological_process											owl:Class	
GO:0003795	biolink:NamedThing	obsolete antimicrobial peptide activity	OBSOLETE. Inhibits the growth of, or directly kills, microbial cells.	tmpzr1t_l9r_go_relaxed.owl	antimicrobial peptide activity					This term was made obsolete because it describes involvement in a process and not a function.	GO:0019730				True			molecular_function											owl:Class	
GO:0052524	biolink:NamedThing	obsolete positive regulation by organism of symbiont salicylic acid-mediated defense response	OBSOLETE. Any process by which an organism activates, maintains or increases the frequency, rate or extent of the salicylic acid-mediated defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	positive regulation by organism of symbiont SA-mediated defense response|induction by organism of symbiont SA-mediated defense response|positive regulation by organism of symbiont salicylic acid-mediated defense response|induction by organism of symbiont salicylic acid-mediated defense response					This term was made obsolete because it does not represent a real biological process.					True			biological_process											owl:Class	
GO:0070321	biolink:NamedThing	obsolete regulation of translation in response to nitrogen starvation	OBSOLETE. Any process that modulates the frequency, rate or extent of the frequency, rate or extent of translation as a result of a stimulus indicating deprivation of nitrogen.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/19092				This term was obsoleted because it was redundant with GO:1903832 ; regulation of cellular response to amino acid starvation.	GO:1903832				True			biological_process											owl:Class	
GO:0019015	biolink:NamedThing	obsolete viral genome	OBSOLETE. The whole of the genetic information of a virus, contained as either DNA or RNA.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it does not represent a GO cellular component.					True			cellular_component											owl:Class	
GO:0015260	biolink:NamedThing	obsolete isethionate channel activity	OBSOLETE. This term was not defined before being made obsolete.	tmpzr1t_l9r_go_relaxed.owl	isethionate channel activity					This term was made obsolete because this solute is transported by an active transporter rather than a channel.					True			molecular_function											owl:Class	
GO:0006484	biolink:NamedThing	obsolete protein cysteine-thiol oxidation	OBSOLETE. Oxidation of two cysteine sulfhydryl groups (thiols) in one protein by a disulfide bond in a second protein to form a disulfide bond in the first protein and two reduced sulfhydryls in the second. The oxidized cysteines linked by a disulfide bond is known as cystine.	tmpzr1t_l9r_go_relaxed.owl	protein cysteine-thiol oxidation					This term was made obsolete because it represents a single activity.	GO:0003756				True			biological_process											owl:Class	
GO:0004171	biolink:NamedThing	obsolete deoxyhypusine synthase activity	OBSOLETE. Catalysis of the reaction: [eIF5A-precursor]-lysine + spermidine = [eIF5A-precursor]-deoxyhypusine + propane-1,3-diamine.	tmpzr1t_l9r_go_relaxed.owl	deoxyhypusine synthase activity|[eIF-5A]-deoxyhypusine synthase					This term was made obsolete because it represents a multistep reaction.	GO:0008612|GO:0034038				True			molecular_function											owl:Class	
GO:1900474	biolink:NamedThing	obsolete negative regulation of mating type switching by negative regulation of transcription from RNA polymerase II promoter	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of mating type switching by stopping, preventing, or reducing the frequency, rate or extent of transcription from an RNA polymerase II promoter.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it represents a GO-CAM model.		dgf	2012-05-01T08:33:18Z		True			biological_process											owl:Class	
GO:0075150	biolink:NamedThing	obsolete regulation of receptor-mediated signal transduction in response to host	OBSOLETE. Any process in which the symbiont organism modulates the frequency, rate or extent of its receptor-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	regulation of symbiont receptor-mediated signal transduction in response to host					This term was obsoleted because there is no evidence that this process exists.					True			biological_process											owl:Class	
GO:0098020	biolink:NamedThing	obsolete virus tail, minor subunit	OBSOLETE. The part of the viral tail that comprises the least common subunit type.	tmpzr1t_l9r_go_relaxed.owl	bacteriophage minor protein subunit|minor tail protein					The reason for obsoletion is that these are not precise structures: major (most abundant) and minor subunits of viral tails vary in different viruses/phages.		bm	2012-07-19T11:36:25Z		True			cellular_component											owl:Class	
GO:0072364	biolink:NamedThing	obsolete regulation of cellular ketone metabolic process by regulation of transcription from RNA polymerase II promoter	OBSOLETE. Any process that modulates the frequency, rate or extent of a cellular ketone metabolic process by modulating the frequency, rate or extent of transcription from an RNA polymerase II promoter.	tmpzr1t_l9r_go_relaxed.owl	regulation of cellular ketone metabolic process by regulation of transcription from an RNA polymerase II promoter|regulation of cellular ketone metabolism by regulation of transcription from an RNA polymerase II promoter					This term was obsoleted because it represents a GO-CAM model.		mah	2010-11-16T03:11:39Z		True			biological_process											owl:Class	
GO:2000530	biolink:NamedThing	obsolete positive regulation of regulation of insulin secretion involved in cellular response to glucose stimulus	OBSOLETE. Any process that activates or increases the frequency, rate or extent of regulation of insulin secretion involved in cellular response to glucose stimulus.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of regulation of insulin secretion in response to glucose|positive regulation of regulation of insulin secretion involved in cellular response to glucose stimulus							yaf	2011-03-24T09:27:37Z		True			biological_process											owl:Class	
GO:0005204	biolink:NamedThing	obsolete chondroitin sulfate proteoglycan	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	chondroitin sulphate proteoglycan|chondroitin sulfate proteoglycan					This term was made obsolete because it describes the composition (i.e. proteoglycan) of a gene product, not a molecular function.					True			molecular_function											owl:Class	
GO:0052357	biolink:NamedThing	obsolete catabolism by host of symbiont cell wall pectin	OBSOLETE. The chemical reactions and pathways performed by an organism resulting in the breakdown of pectin in the symbiont cell wall. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/21396				This term was obsoleted because there is no evidence it exists.					True			biological_process											owl:Class	
GO:0044009	biolink:NamedThing	obsolete viral transmission by vector	OBSOLETE. The transfer of virions by means of an organism (often an insect or other animal) in order to create new infection.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it did not represent a specific process, but represented the life cycle of a virus.					True			biological_process											owl:Class	
GO:0007570	biolink:NamedThing	obsolete age dependent accumulation of genetic damage	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	age dependent accumulation of genetic damage					This term was made obsolete because it does not describe a biological process.	GO:0001301				True			biological_process											owl:Class	
GO:0006504	biolink:NamedThing	obsolete C-terminal protein geranylgeranylation	OBSOLETE. The covalent or non-covalent attachment of a geranylgeranyl group to the carboxy-terminus of a protein.	tmpzr1t_l9r_go_relaxed.owl	C-terminal protein geranylgeranylation			GO:0018344		This term was made obsolete because the process is not exclusive to the carboxy-terminus of a protein.					True			biological_process											owl:Class	
GO:0010156	biolink:NamedThing	obsolete sporocyte morphogenesis	OBSOLETE. Formation and development of sporocyte, the haploid spores of angiosperms which are initiated by the differentiation of a subset of floral cells into sporocytes, which then undergo meiotic divisions to form microspores and megaspores.	tmpzr1t_l9r_go_relaxed.owl	sporocyte morphogenesis					This term was made obsolete because it was incorrectly defined.	GO:0048533				True			biological_process											owl:Class	
GO:0044142	biolink:NamedThing	obsolete positive regulation of growth of symbiont on or near host surface	OBSOLETE. Any process that activates or increases the frequency, rate or extent of the symbiont's increase in size or mass on or near the cells or tissues of the host organism.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it was partially redundant with other terms and its usage has been inconsistent.		jl	2009-08-06T01:35:18Z		True			biological_process											owl:Class	
GO:1990653	biolink:NamedThing	obsolete monounsaturated fatty acid biosynthetic process	OBSOLETE. The chemical reactions and pathways resulting in the formation of a monounsaturated fatty acid. A monounsaturated fatty acid has one double bond in the fatty acid chain with all of the remainder carbon atoms being single-bonded, as opposed to polyunsaturated fatty acids.	tmpzr1t_l9r_go_relaxed.owl						For example, stearoyl-coenzyme A desaturase (Scd) catalyzes the desaturation of saturated fatty acids to monounsaturated fatty acids in mammals and yeast.		hjd	2015-02-23T18:59:15Z		True			biological_process											owl:Class	
GO:0009781	biolink:NamedThing	obsolete photosynthetic water oxidation	OBSOLETE. Processes by which a molecule of water is oxidized during photosynthesis. P680+, the photochemically oxidized reaction-center chlorophyll of PSII, is a strong biological oxidant. The reduction potential of P680+ is more positive than that of water, and thus it can oxidize water to give O2 and H+ ions. The oxygen escapes as a gas while the H+ ions remain in solution inside the thylakoid vesicle.	tmpzr1t_l9r_go_relaxed.owl	photosynthetic water oxidation			GO:0010242		This term was made obsolete because it represents a molecular function.					True			biological_process											owl:Class	
GO:0052411	biolink:NamedThing	obsolete metabolism by organism of cell wall chitin in other organism involved in symbiotic interaction	OBSOLETE. The chemical reactions and pathways performed by an organism involving chitin in the cell wall of a second organism, where the two organisms are in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	metabolism by organism of cell wall chitin in other organism during symbiotic interaction	https://github.com/geneontology/go-ontology/issues/21396				This term was obsoleted because it represents an unnecessary grouping class.					True			biological_process											owl:Class	
GO:0005531	biolink:NamedThing	obsolete galactose binding lectin	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	galactose binding lectin					This term was made obsolete because it refers to a class of gene products.	GO:0007157|GO:0005534				True			molecular_function											owl:Class	
GO:0003819	biolink:NamedThing	obsolete major histocompatibility complex antigen	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	major histocompatibility complex antigen|MHC protein					This term was made obsolete because it represents a gene product, and because describing something as an 'antigen' means that an organism can produce antibodies to it, which says nothing about the gene product activity.					True			molecular_function											owl:Class	
GO:0072668	biolink:NamedThing	obsolete tubulin complex biogenesis	OBSOLETE. A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a tubulin complex. Includes the synthesis and folding of the constituent protein molecules, and those protein modifications that are involved in synthesis or assembly of the complex. A tubulin complex is a heterodimer of tubulins alpha and beta, from which microtubules are assembled.	tmpzr1t_l9r_go_relaxed.owl	tubulin complex biogenesis			GO:0007021		This term was obsoleted because biogenesis should only be used for complexes where synthesis of some non-protein component is necessary for assembly.		mah	2011-02-14T03:25:18Z		True			biological_process											owl:Class	
GO:1990219	biolink:NamedThing	obsolete positive regulation by symbiont of host protein levels	OBSOLETE. Any process in which an organism activates, maintains or increases the frequency, rate or extent of protein levels in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it is a readout, and annotations should be made to more informative terms.		ml	2013-10-10T17:26:03Z		True			biological_process											owl:Class	
GO:0008638	biolink:NamedThing	obsolete protein tagging activity	OBSOLETE. Covalent addition of a specific tagging molecule to a protein, targeting the tagged protein for some fate e.g. degradation.	tmpzr1t_l9r_go_relaxed.owl	protein tagging activity					This term was made obsolete because it represents a biological process and a molecular function.	GO:0031386|GO:0005515|GO:0006464				True			molecular_function											owl:Class	
GO:0007125	biolink:NamedThing	obsolete invasive growth	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	invasive growth					This term was made obsolete because it has been split into two new terms.	GO:0001403|GO:0044409				True			biological_process											owl:Class	
GO:1990149	biolink:NamedThing	obsolete COPI vesicle coating	OBSOLETE. The addition of COPI proteins and adaptor proteins to ER membranes during the formation of transport vesicles, forming a vesicle coat.	tmpzr1t_l9r_go_relaxed.owl	COPI vesicle coating					This term was obsoleted at the TermGenie Gatekeeper stage because COPI vesicles are formed on Golgi membranes, and the existing term 'COPI coating of Golgi vesicle ; GO:0048205' describes this process.		rb	2013-07-29T22:09:37Z		True			biological_process											owl:Class	
GO:0038073	biolink:NamedThing	obsolete MAP kinase kinase kinase activity involved in conjugation with cellular fusion	OBSOLETE. Catalysis of the phosphorylation and activation of a MAP kinase kinase (MAPKK), as part of a MAPK signaling cascade that contributes to cell wall biogenesis.	tmpzr1t_l9r_go_relaxed.owl	MAPKKK activity involved in conjugation with cellular fusion|MAP3K activity involved in conjugation with cellular fusion					This term has been obsoleted because it represents a GO-CAM model rather than a single GO term.		bf	2012-01-26T02:31:57Z		True			molecular_function											owl:Class	
GO:0007149	biolink:NamedThing	obsolete colony morphology	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	colony morphology					This term was made obsolete because it describes a phenotype rather than a biological goal.					True			biological_process											owl:Class	
GO:0017114	biolink:NamedThing	obsolete wide-spectrum protease inhibitor activity	OBSOLETE. Stops, prevents or reduces the activity of a protease by a wide-spectrum protease inhibitor. A wide-spectrum protease inhibitor is a protein having a peptide stretch which contains specific cleavage sites for different proteinases enabling inhibition of all four classes of proteinases by formation of a covalent bond between the inhibitor and the protease.	tmpzr1t_l9r_go_relaxed.owl	wide-spectrum protease inhibitor activity|wide-spectrum proteinase inhibitor			GO:0030414		This term was made obsolete because it represents a regulator of non-existent molecular function.					True			molecular_function											owl:Class	
GO:0052408	biolink:NamedThing	obsolete metabolism by host of symbiont cell wall cellulose	OBSOLETE. The chemical reactions and pathways performed by an organism involving cellulose in the cell wall of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/21469				This term was obsoleted because it represents a molecular function.					True			biological_process											owl:Class	
GO:0016552	biolink:NamedThing	obsolete cotranscriptional insertion or deletion editing	OBSOLETE. The insertion into or deletion from an RNA molecule of nucleotide residues not encoded in DNA; takes place during transcription.	tmpzr1t_l9r_go_relaxed.owl	cotranscriptional insertion/deletion editing|cotranscriptional insertion or deletion editing					This term was made obsolete because it represents two separate processes (insertion and deletion).	GO:0070705|GO:0070706				True			biological_process											owl:Class	
GO:0052230	biolink:NamedThing	obsolete modulation of intracellular transport in other organism involved in symbiotic interaction	OBSOLETE. Any process in which an organism modulates the frequency, rate or extent of the directed movement of substances within the cell or cells of a second organism, where the two organisms are in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	modulation of intracellular trafficking in other organism|modulation of intracellular transport in other organism during symbiotic interaction					This term was obsoleted because it represents an unnecessary grouping class.					True			biological_process											owl:Class	
GO:0044130	biolink:NamedThing	obsolete negative regulation of growth of symbiont in host	OBSOLETE. Any process in which the symbiont stops, prevents or reduces its increase in size or mass within the cells or tissues of the host organism. The host is defined as the larger of the organisms involved in the symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it was partially redundant with other terms and its usage has been inconsistent.		jl	2009-08-04T02:42:25Z		True			biological_process											owl:Class	
GO:0006774	biolink:NamedThing	obsolete vitamin B12 reduction	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	vitamin B12 reduction					This term was made obsolete because it represents a molecular function rather than a biological process.	GO:0009235|GO:0050453				True			biological_process											owl:Class	
GO:0038068	biolink:NamedThing	obsolete MAP kinase kinase activity involved in cell wall organization or biogenesis	OBSOLETE. Catalysis of the concomitant phosphorylation of threonine (T) and tyrosine (Y) residues in a Thr-Glu-Tyr (TEY) thiolester sequence in a MAP kinase (MAPK) substrate, as part of a MAPK signaling cascade that contributes to cell wall organization or biogenesis.	tmpzr1t_l9r_go_relaxed.owl	MAP kinase kinase activity involved in cell wall biogenesis|MAPKK activity involved in cell wall integrity|MAP2K activity involved in cell wall integrity					This term has been obsoleted because it represents a GO-CAM model rather than a single GO term.		bf	2012-01-25T03:34:10Z		True			molecular_function											owl:Class	
GO:0015040	biolink:NamedThing	obsolete electron transfer flavoprotein, group I	OBSOLETE. An electron transfer flavoprotein that functions as a housekeeping protein that links acyl-CoA dehydrogenase reactions with the respiratory chain, such as in the fatty acid degradation pathway.	tmpzr1t_l9r_go_relaxed.owl	electron transfer flavoprotein, group I			GO:0009055		This term was made obsolete because it refers to a class of gene products.					True			molecular_function											owl:Class	
GO:0075014	biolink:NamedThing	obsolete growth or development of symbiont on or near host rhizosphere	OBSOLETE. The increase in size or mass of symbiont, or the progression of the symbiont from an initial condition to a later condition, occurring on or near its host rhizosphere. The host rhizosphere is defined as total below-ground surfaces of a plant as a habitat for its symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	growth or development of symbiont on or near host rhizosphere										True			biological_process											owl:Class	
GO:0004201	biolink:NamedThing	obsolete caspase-1 activity	OBSOLETE. Catalysis of the release of interleukin 1-beta by specific cleavage of Asp116-Ala117 and Asp27-Gly28 bonds in precursor. Enzymes with this function can also hydrolyze the terminal bond in the small-molecule substrate, Ac-Tyr-Val-Ala-Asp-NHMec.	tmpzr1t_l9r_go_relaxed.owl	caspase-1 activity|ICE			GO:0004197		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0005241	biolink:NamedThing	obsolete inward rectifier channel	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	inward rectifier channel					This term was made obsolete because more specific terms were created.	GO:0005242				True			molecular_function											owl:Class	
GO:0052012	biolink:NamedThing	obsolete catabolism by symbiont of host cell wall chitin	OBSOLETE. The chemical reactions and pathways performed by an organism resulting in the breakdown of chitin in the host cell wall. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	catabolism by organism of host cell wall chitin	https://github.com/geneontology/go-ontology/issues/21469				This term was obsoleted because it represents a molecular function.					True			biological_process											owl:Class	
GO:0052888	biolink:NamedThing	obsolete dihydroorotate oxidase (fumarate) activity	OBSOLETE. Catalysis of the reaction: (S)-dihydroorotate + fumarate = orotate + succinate.	tmpzr1t_l9r_go_relaxed.owl	DHOdase activity|DHodehase activity|DHOD activity|dihydroorotate dehydrogenase activity|dihydoorotic acid dehydrogenase activity|dihydroorotate oxidase (fumarate) activity|dihydroorotate oxidase activity				EC:1.3.98.1|MetaCyc:RXN-9929|KEGG_REACTION:R01867	EC has determined that this reaction in fact does not exist and have withdrawn EC:1.3.3.1. Note: If fumarate is not shown to be involved, you may want to consider GO:0004152, dihydroorotate dehydrogenase activity (parent term); if the reaction involves fumarate, then use GO:0052888 dihydroorotate oxidase (fumarate) activity. Details at http://sourceforge.net/p/geneontology/ontology-requests/10770/, RHEA:30059 and EC:1.3.98 removed so as not to conflict with remapping					True			molecular_function											owl:Class	
GO:0051727	biolink:NamedThing	obsolete cell cycle switching, meiotic to mitotic cell cycle	OBSOLETE. The process in which a cell switches cell cycle mode from meiotic to mitotic division.	tmpzr1t_l9r_go_relaxed.owl	conversion to mitosis|cell cycle switching, meiosis to mitosis|initiation of mitotic cell cycle|entry into mitosis|conversion to mitotic cell cycle|initiation of mitosis|cell cycle switching, meiotic to mitotic cell cycle|entry into mitotic cell cycle|mitotic entry					This term was made obsolete because it does not refer to a real biological process.					True			biological_process											owl:Class	
GO:0090579	biolink:NamedThing	obsolete dsDNA loop formation	OBSOLETE. The formation and maintenance of DNA loops that juxtapose separated regions on the same dsDNA molecule.	tmpzr1t_l9r_go_relaxed.owl	chromatin looping|dsDNA looping	https://github.com/geneontology/go-ontology/issues/20204				This term was obsoleted because it was defined like a molecular function.	GO:0140587	tb	2014-05-12T14:45:58Z		True			biological_process											owl:Class	
GO:0030365	biolink:NamedThing	obsolete cleavage stimulation factor activity	OBSOLETE. A factor is necessary for cleavage but not for poly(A) addition in mRNA 3' end processing; can stimulate poly(A) addition on substrates with a CstF binding site upstream of the AAUAAA hexanucleotide.	tmpzr1t_l9r_go_relaxed.owl	cleavage stimulation factor activity|CstF			GO:0005848		This term was made obsolete because it describes a cellular component.	GO:0006379				True			molecular_function											owl:Class	
GO:0003716	biolink:NamedThing	obsolete RNA polymerase I transcription termination factor activity	OBSOLETE. Any activity that brings about termination of transcription by RNA polymerase I.	tmpzr1t_l9r_go_relaxed.owl	Pol I transcription termination factor activity|RNA polymerase I transcription termination factor activity					This term was obsoleted because it is essentially identical to a Process term (specifically the Biological Process term which has been selected as a term to consider for reannotation), i.e. it is defined only in terms of the process it acts in and it does NOT convey any information about the molecular nature of the function or whether the function is based on binding DNA, on interacting with other proteins, or some other mechanism. To transfer all annotations without review, the BP term indicated is considered to be equivalent and thus the only appropriate destination for all annotations. To reannotate to a MF term, you will probably need to revisit the original literature or other primary data because this "MF" term was not defined in terms of mechanism of action and there are multiple possibilities in the revised MF structure. In reannotation, please also consider descendent terms of the suggested MF terms as a more specific term may be more appropriate than the MF terms indicated. Please be aware that you may wish to request a new term if the mechanism of action of this gene product is not yet represented or if you are annotating for an RNAP different than one for which there is a specific suggested term. Also note that if there is no information about how the gene product acts, it may be appropriate to annotate to the root term for molecular_function.	GO:0006363				True			molecular_function											owl:Class	
RO:0002014	biolink:NamedThing	has negative regulatory component activity		tmpzr1t_l9r_go_relaxed.owl					RO:0002014									external									has_negative_regulatory_component_activity			
GO:0004195	biolink:NamedThing	obsolete renin activity	OBSOLETE. Catalysis of the cleavage of Leu-Xaa bond in angiotensinogen to generate angiotensin I.	tmpzr1t_l9r_go_relaxed.owl	renin activity|angiotensinogenase activity|angiotensin-forming enzyme activity			GO:0004190		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:1990187	biolink:NamedThing	obsolete protein localization to mRNA	OBSOLETE. A process in which a protein is transported to, or maintained at mRNA.	tmpzr1t_l9r_go_relaxed.owl	protein localization to mRNA					This term was obsoleted at the TermGenie Gatekeeper stage.		rb	2013-09-11T18:19:20Z		True			biological_process											owl:Class	
GO:0046894	biolink:NamedThing	obsolete enzyme active site formation via S-amidino-L-cysteine	OBSOLETE. Active site formation via the transient amidinylation of peptidyl-cysteine to form peptidyl-S-amidino-L-cysteine.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/15594				This term was obsoleted because it represents a reaction intermediate, not a biological process, see PMID:9148748.	GO:0015068				True			biological_process											owl:Class	
GO:0052095	biolink:NamedThing	obsolete formation of specialized structure for nutrient acquisition from other organism involved in symbiotic interaction	OBSOLETE. The assembly by an organism of a cellular component or anatomical structure for the purpose of obtaining nutrients from a second organism, where the two organisms are in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	formation of specialized structure for nutrient acquisition from other organism during symbiotic interaction					This term was obsoleted because it represents an unnecessary grouping class.					True			biological_process											owl:Class	
GO:0046139	biolink:NamedThing	obsolete coenzyme and prosthetic group catabolic process	OBSOLETE. The chemical reactions and pathways resulting in the breakdown of coenzymes and prosthetic groups.	tmpzr1t_l9r_go_relaxed.owl	coenzyme and prosthetic group breakdown|coenzyme and prosthetic group catabolism|coenzyme and prosthetic group degradation|coenzyme and prosthetic group catabolic process					This term was made obsolete because it was replaced by more specific terms.	GO:0051190				True			biological_process											owl:Class	
GO:0052119	biolink:NamedThing	obsolete negative energy taxis in host environment	OBSOLETE. The directed movement of a motile cell or organism on, within or near its host organism towards a lower level of a physical stimulus involved in energy generation, such as light, oxygen, and oxidizable substrates. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	negative energy taxis in response to host environment	https://github.com/geneontology/go-ontology/issues/18819				This term was obsoleted because it represents both a process and a location.					True			biological_process											owl:Class	
GO:1903230	biolink:NamedThing	obsolete miRNA binding involved in posttranscriptional gene silencing	OBSOLETE. Any miRNA binding that is involved in posttranscriptional gene silencing.	tmpzr1t_l9r_go_relaxed.owl	miRNA binding involved in quelling|microRNA binding involved in quelling|microRNA binding involved in post-transcriptional gene silencing|microRNA binding involved in PTGS|miRNA binding involved in posttranscriptional gene silencing|miRNA binding involved in PTGS|microRNA binding involved in cosuppression|miRNA binding involved in cosuppression|miRNA binding involved in post-transcriptional gene silencing|microRNA binding involved in posttranscriptional gene silencing					This term was obsoleted at the TermGenie Gatekeeper stage.		jl	2014-07-31T10:22:18Z		True			molecular_function											owl:Class	
GO:0085022	biolink:NamedThing	obsolete modification by symbiont of host morphology or physiology via protein secreted by type VI secretion system	OBSOLETE. The process in which an organism effects a change in the structure or function of its host organism, mediated by a substance secreted by a type VI secretion system in the organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it conflated the process in which a gene product is involved with the secretion system by which it reaches its target.		jl	2010-07-09T03:32:02Z		True			biological_process											owl:Class	
GO:0052058	biolink:NamedThing	obsolete modification by symbiont of host morphology or physiology via substance secreted by type IV secretion system	OBSOLETE. The process in which an organism effects a change in the structure or function of its host organism, mediated by a substance secreted by a type IV secretion system in the organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it conflated the process in which a gene product is involved with the secretion system by which it reaches its target.					True			biological_process											owl:Class	
GO:0052207	biolink:NamedThing	obsolete modification of morphology or physiology of other organism via protein secreted by type III secretion system involved in symbiotic interaction	OBSOLETE. The process in which an organism effects a change in the structure or function of a second organism, mediated by a substance secreted by a type III secretion system in the first organism, where the two organisms are in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	modification of morphology or physiology of other organism via protein secreted by type III secretion system during symbiotic interaction					This term was obsoleted because it conflated the process in which a gene product is involved with the secretion system by which it reaches its target.					True			biological_process											owl:Class	
GO:0000284	biolink:NamedThing	obsolete shmoo orientation	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	shmoo orientation			GO:0000753		This term was made obsolete because it is an organism specific term. The entire branch of the ontology was reorganized to be more generally applicable.					True			biological_process											owl:Class	
GO:0021883	biolink:NamedThing	obsolete cell cycle arrest of committed forebrain neuronal progenitor cell	OBSOLETE. The process in which the cell cycle is halted during one of the normal phases (G1, S, G2, M) in a cell that has been committed to become a neuron that will reside in the forebrain.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/20988				This term was obsoleted because it represents a GO-CAM model.					True			biological_process											owl:Class	
GO:0016637	biolink:NamedThing	obsolete oxidoreductase activity, acting on the CH-CH group of donors, other acceptors	OBSOLETE. Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces an acceptor other than quinone or related compound, a cytochrome, an iron-sulfur protein, NAD, NADP or oxygen.	tmpzr1t_l9r_go_relaxed.owl	oxidoreductase activity, acting on the CH-CH group of donors, other acceptors					This term was made obsolete because it was an unnecessary grouping term.	GO:0016627				True			molecular_function											owl:Class	
GO:0030161	biolink:NamedThing	obsolete calpain inhibitor activity	OBSOLETE. Stops, prevents or reduces the activity of the enzyme calpain, which catalyzes of the preferential cleavage of Tyr-Xaa, Met-Xaa or Arg-Xaa with Leu or Val as the P2 residue.	tmpzr1t_l9r_go_relaxed.owl	calpain inhibitor activity			GO:0010859		This term was made obsolete because it represents a regulator of a non-existent molecular function.					True			molecular_function											owl:Class	
GO:0016683	biolink:NamedThing	obsolete oxidoreductase activity, acting on diphenols and related substances as donors, other acceptors	OBSOLETE. Catalysis of an oxidation-reduction (redox) reaction in which a diphenol, or related compound, acts as a hydrogen or electron donor and reduces an acceptor other than a cytochrome, NAD, NADP or oxygen.	tmpzr1t_l9r_go_relaxed.owl	oxidoreductase activity, acting on diphenols and related substances as donors, other acceptors					This term was made obsolete because it was an unnecessary grouping term.	GO:0016679				True			molecular_function											owl:Class	
GO:2000498	biolink:NamedThing	obsolete regulation of induction of apoptosis in response to chemical stimulus	OBSOLETE. Any process that modulates the frequency, rate or extent of induction of apoptosis in response to chemical stimulus.	tmpzr1t_l9r_go_relaxed.owl	regulation of induction of apoptosis in response to chemical stimulus|regulation of induction of apoptosis in response to chemical substance					This term was made obsolete because it is ill-defined.		yaf	2011-03-18T02:34:53Z		True			biological_process											owl:Class	
GO:0046194	biolink:NamedThing	obsolete pentachlorophenol biosynthetic process	OBSOLETE. The chemical reactions and pathways resulting in the formation of pentachlorophenol, a chlorinated insecticide and fungicide used primarily to protect timber from fungal rot and wood boring insects. Pentachlorophenol is significantly toxic to mammals, plants, and many microorganisms.	tmpzr1t_l9r_go_relaxed.owl	pentachlorophenol anabolism|pentachlorophenol synthesis|pentachlorophenol biosynthetic process|pentachlorophenol biosynthesis|pentachlorophenol formation			GO:0018961		This term was made obsolete because pentachlorophenol is not synthesized by living organisms and GO does not cover non-biological processes.					True			biological_process											owl:Class	
GO:0017028	biolink:NamedThing	obsolete protein stabilization activity	OBSOLETE. Strengthening of a bond between proteins. Proteins are large molecules composed of one or more chains of amino acids. The amino acids are joined in a specific order by peptide bonds.	tmpzr1t_l9r_go_relaxed.owl	protein stabilization activity			GO:0050821		This term was made obsolete because it represents a biological process.					True			molecular_function											owl:Class	
GO:0016650	biolink:NamedThing	obsolete oxidoreductase activity, acting on the CH-NH group of donors, other acceptors	OBSOLETE. Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH group acts as a hydrogen or electron donor and reduces an acceptor other than quinone or similar compound, disulfide, NAD, NADP, oxygen or a flavin.	tmpzr1t_l9r_go_relaxed.owl	oxidoreductase activity, acting on the CH-NH group of donors, other acceptors					This term was made obsolete because it was an unnecessary grouping term.	GO:0016645				True			molecular_function											owl:Class	
GO:0097031	biolink:NamedThing	obsolete mitochondrial respiratory chain complex I biogenesis	OBSOLETE. The biogenesis of a mitochondrial respiratory chain complex I, a protein complex located in the mitochondrial inner membrane that forms part of the mitochondrial respiratory chain. Includes the synthesis of constituent proteins and their aggregation, arrangement and bonding together.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/15173				The reason for obsoletion is that 'biogenesis' as related to a protein is translation, and there is no indication that the members of these complexes are synthesized in a particular way. Historically biogenesis terms were created for some processes when the level of a molecule was changed by an unknown mechanism, for instance transcription, translation, assembly etc. This is now considered too indirect for annotation.		pr	2011-04-05T02:53:14Z		True			biological_process											owl:Class	
GO:0046241	biolink:NamedThing	obsolete m-xylene biosynthetic process	OBSOLETE. The chemical reactions and pathways resulting in the formation of m-xylene, 1,3-dimethylbenzene, a colorless, liquid aromatic hydrocarbon.	tmpzr1t_l9r_go_relaxed.owl	meta-xylene biosynthesis|m-xylene biosynthesis|meta-xylene biosynthetic process|m-xylene synthesis|m-xylene anabolism|m-xylene formation|m-xylene biosynthetic process			GO:0018949		This term was made obsolete because m-xylene is not synthesized by living organisms, and GO does not cover non-biological processes.					True			biological_process											owl:Class	
GO:0008019	biolink:NamedThing	obsolete macrophage receptor activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	macrophage receptor activity					This term was made obsolete because its name is ambiguous, and it was never defined.	GO:0038187|GO:0005044				True			molecular_function											owl:Class	
GO:0102132	biolink:NamedThing	obsolete 3-oxo-pimeloyl-[acp] methyl ester reductase activity	OBSOLETE. Catalysis of the reaction: NADP + a 3R-hydroxypimeloyl-[acp] methyl ester <=> NADPH + H+ + a 3-oxo-pimeloyl-[acp] methyl ester.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/21876				This term was obsoleted because it represents a specific substrate, and is beyond the specificity of GO.	GO:0004316				True			molecular_function											owl:Class	
GO:0005074	biolink:NamedThing	obsolete inhibitory SMAD protein	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	inhibitory SMAD protein					This term was made obsolete because it names a family of gene products.					True			molecular_function											owl:Class	
GO:0075115	biolink:NamedThing	obsolete modulation by symbiont of host transmembrane receptor-mediated cAMP signal transduction	OBSOLETE. Any process in which the symbiont modulates the frequency, rate or extent of host transmembrane receptor-mediated cAMP signal transduction. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	modulation by symbiont of host transmembrane receptor-mediated cAMP signaling					The reason for obsoletion is that there is no evidence that this process exists.					True			biological_process											owl:Class	
GO:0052523	biolink:NamedThing	obsolete positive regulation by organism of symbiont programmed cell death	OBSOLETE. Any process by which an organism activates, maintains or increases the frequency, rate or extent of programmed cell death in the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	positive regulation by organism of symbiont programmed cell death|enhancement or induction of symbiont programmed cell death					This term was made obsolete because it does not represent a real biological process.					True			biological_process											owl:Class	
GO:0005888	biolink:NamedThing	obsolete proteoglycan integral to plasma membrane	OBSOLETE. Penetrating at least one phospholipid bilayer of a plasma membrane and consisting of proteoglycan. Also refers to the state of being buried in the bilayer with no exposure outside the bilayer.	tmpzr1t_l9r_go_relaxed.owl	proteoglycan integral to plasma membrane			GO:0005887		This term was made obsolete because it describes the composition (i.e. proteoglycan) and not the location of a gene product.					True			cellular_component											owl:Class	
GO:1990479	biolink:NamedThing	obsolete response to lipoic acid	OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipoic acid stimulus.	tmpzr1t_l9r_go_relaxed.owl	response to 5-(1,2-dithiolan-3-yl)pentanoic acid					This term was obsoleted at the TermGenie Gatekeeper stage.		sl	2014-09-09T22:20:41Z		True			biological_process											owl:Class	
GO:0075234	biolink:NamedThing	obsolete zoospore movement on or near host	OBSOLETE. Any process involved in the directed movement of a zoospore on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	zoospore motility on or near host					This term was obsoleted because it represented both a process and a location.					True			biological_process											owl:Class	
GO:0085023	biolink:NamedThing	obsolete modification by symbiont of host morphology or physiology via protein secreted by type VII secretion system	OBSOLETE. The process in which an organism effects a change in the structure or function of its host organism, mediated by a substance secreted by a type VII secretion system in the organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it conflated the process in which a gene product is involved with the secretion system by which it reaches its target.		jl	2010-07-09T03:35:02Z		True			biological_process											owl:Class	
GO:0002146	biolink:NamedThing	obsolete steroid hormone receptor import into nucleus	OBSOLETE. The directed movement of a steroid hormone receptor into the nucleus.	tmpzr1t_l9r_go_relaxed.owl	steroid hormone receptor nuclear translocation					The reason for obsoletion is that all proteins are imported into the nucleus via the same mechanism, so the import of individual proteins should be captured with extensions or by GO-CAM models.	GO:0006606|GO:0042306	hjd	2009-07-09T02:34:42Z		True			biological_process											owl:Class	
GO:0016734	biolink:NamedThing	obsolete molybdenum-iron nitrogenase activity	OBSOLETE. Catalysis of the reaction: 8 reduced ferredoxin + 8 H+ + N2 + 16 ATP = 8 oxidized ferredoxin + 2 NH3 + 16 ADP + 16 phosphate.	tmpzr1t_l9r_go_relaxed.owl	molybdenum-iron nitrogenase activity					This term was made obsolete because it represents a cellular component.	GO:0016612|GO:0016163				True			molecular_function											owl:Class	
GO:0008341	biolink:NamedThing	obsolete response to cocaine (sensu Insecta)	OBSOLETE. A change in state or activity of a mature individual as the result of a cocaine stimulus. As in, but not restricted to, the true insects (Insecta, ncbi_taxonomy_id:50557).	tmpzr1t_l9r_go_relaxed.owl	response to cocaine (sensu Insecta)					This term was made obsolete because there is no clear difference between the sensu Insecta term and the generic term.	GO:0048148				True			biological_process											owl:Class	
GO:0006125	biolink:NamedThing	obsolete thioredoxin pathway	OBSOLETE. This term was not defined before being made obsolete.	tmpzr1t_l9r_go_relaxed.owl	thioredoxin pathway|thioredoxin reduction				MetaCyc:THIOREDOX-PWY	This term was made obsolete because it is not clear what it is intended to represent.	GO:0045454				True			biological_process											owl:Class	
GO:0008133	biolink:NamedThing	obsolete collagenase activity	OBSOLETE. Was not defined before being made obsolete.	tmpzr1t_l9r_go_relaxed.owl	collagenase activity			GO:0004222		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0008166	biolink:NamedThing	obsolete viral replication	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	viral replication					This term was made obsolete because it covers multiple processes and is now covered by more specific terms.	GO:0019079				True			biological_process											owl:Class	
GO:0021864	biolink:NamedThing	obsolete radial glial cell division in forebrain	OBSOLETE. The mitotic division of radial glial cells in the developing forebrain.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it represents a GO-CAM model.					True			biological_process											owl:Class	
GO:0003797	biolink:NamedThing	obsolete antibacterial peptide activity	OBSOLETE. Inhibits the growth of, or directly kills, bacterial cells.	tmpzr1t_l9r_go_relaxed.owl	antibacterial peptide activity					This term was made obsolete because it describes involvement in a process and not a function.	GO:0042742				True			molecular_function											owl:Class	
RO:0000056	biolink:NamedThing	participates_in		tmpzr1t_l9r_go_relaxed.owl					RO:0000056									external									participates_in			
OIO:hasScope	biolink:NamedThing	has_scope		tmpzr1t_l9r_go_relaxed.owl																									owl:AnnotationProperty	
GO:0008018	biolink:NamedThing	obsolete structural protein of chorion (sensu Drosophila)	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	structural protein of chorion (sensu Drosophila)			GO:0005213		This term was made obsolete because the function is covered by a parent term.					True			molecular_function											owl:Class	
GO:0075164	biolink:NamedThing	obsolete negative regulation of G-protein beta subunit-mediated signal transduction in response to host	OBSOLETE. Any process in which the symbiont organism stops, prevents, or reduces the frequency, rate or extent of its symbiont G-protein beta subunit-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of symbiont G-protein beta subunit-mediated signal transduction in response to host					This term was obsoleted because there is no evidence that this process exists.					True			biological_process											owl:Class	
GO:0007240	biolink:NamedThing	obsolete nuclear translocation of Hog1	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	nuclear translocation of Hog1					This term was made obsolete because it contains gene product and species specific information.					True			biological_process											owl:Class	
GO:0006155	biolink:NamedThing	obsolete adenosine deaminase reaction	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	adenosine deaminase reaction			GO:0004000		This term was made obsolete because it represents a molecular function.					True			biological_process											owl:Class	
GO:0000185	biolink:NamedThing	obsolete activation of MAPKKK activity	OBSOLETE. Any process that initiates the activity of the inactive enzyme MAP kinase kinase kinase (MAPKKK).	tmpzr1t_l9r_go_relaxed.owl	activation of MAP3K activity|positive regulation of MAP kinase kinase kinase activity|activation of MAP kinase kinase kinase|activation of MAPKKK activity during sporulation|positive regulation of MAPKKK activity	https://github.com/geneontology/go-ontology/issues/21307				This term was obsoleted because it represents a molecular function.	GO:0000165|GO:0043539				True			biological_process											owl:Class	
GO:0017027	biolink:NamedThing	obsolete transmembrane receptor protein serine/threonine kinase receptor-associated protein activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	transmembrane receptor protein serine/threonine kinase receptor-associated protein activity					This term was made obsolete because it represents a gene product and not a molecular function.	GO:0005102|GO:0005515				True			molecular_function											owl:Class	
GO:0052514	biolink:NamedThing	obsolete positive regulation by organism of symbiont inflammatory response	OBSOLETE. Any process by which an organism activates, maintains or increases the frequency, rate or extent of the inflammatory response of a symbiont organism; the inflammatory response is the immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	positive regulation by organism of symbiont inflammatory response					This term was made obsolete because it does not represent a real biological process.					True			biological_process											owl:Class	
GO:0003902	biolink:NamedThing	obsolete DNA-directed RNA polymerase III activity	OBSOLETE. Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1).	tmpzr1t_l9r_go_relaxed.owl	DNA-directed RNA polymerase III activity			GO:0003899		This term was made obsolete because it represents the specific complex represented by the cellular component term 'DNA-directed RNA polymerase III complex ; GO:0005666'.					True			molecular_function											owl:Class	
GO:0006410	biolink:NamedThing	obsolete transcription, RNA-dependent	OBSOLETE. The cellular synthesis of DNA on a template of RNA.	tmpzr1t_l9r_go_relaxed.owl	transcription, RNA-dependent					This term was obsoleted because the name and the definition mean two completely different things: 1) "transcription, RNA-dependent", i.e. RNA-dependent production of an RNA transcript and 2) "reverse transcription", i.e. RNA-dependent DNA synthesis.					True			biological_process											owl:Class	
GO:0044825	biolink:NamedThing	obsolete retroviral strand transfer activity	OBSOLETE. Catalysis of the covalent insertion of processed 3'-viral DNA ends into host chromosomal DNA by a trans-esterification reaction.	tmpzr1t_l9r_go_relaxed.owl	strand transfer reaction	https://github.com/geneontology/go-ontology/issues/21721				This term was obsoleted because it represents part of an activity.	GO:0044823	jl	2014-02-04T15:16:39Z		True			molecular_function											owl:Class	
GO:0016943	biolink:NamedThing	obsolete RNA polymerase I transcription elongation factor activity	OBSOLETE. Any activity that modulates the rate of transcription elongation, the addition of ribonucleotides to an RNA molecule catalyzed by RNA polymerase I following transcription initiation.	tmpzr1t_l9r_go_relaxed.owl	RNA polymerase I transcription elongation factor activity|Pol I transcription elongation factor activity					This term was obsoleted because it is essentially identical to a Process term (specifically the Biological Process term which has been selected as a term to consider for reannotation), i.e. it is defined only in terms of the process it acts in and it does NOT convey any information about the molecular nature of the function or whether the function is based on binding DNA, on interacting with other proteins, or some other mechanism. To transfer all annotations without review, the BP term indicated is considered to be equivalent and thus the only appropriate destination for all annotations. To reannotate to a MF term, you will probably need to revisit the original literature or other primary data because this "MF" term was not defined in terms of mechanism of action and there are multiple possibilities in the revised MF structure. In reannotation, please also consider descendent terms of the suggested MF terms as a more specific term may be more appropriate than the MF terms indicated. Please be aware that you may wish to request a new term if the mechanism of action of this gene product is not yet represented or if you are annotating for an RNAP different than one for which there is a specific suggested term. Also note that if there is no information about how the gene product acts, it may be appropriate to annotate to the root term for molecular_function.	GO:0006362				True			molecular_function											owl:Class	
GO:2001275	biolink:NamedThing	obsolete positive regulation of glucose import in response to insulin stimulus	OBSOLETE. Any process that activates or increases the frequency, rate or extent of glucose import in response to insulin stimulus.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of cellular glucose import in response to insulin stimulus	https://github.com/geneontology/go-ontology/issues/15961				This term was obsoleted because it represents a GO-CAM model.		vk	2011-12-13T12:29:43Z		True			biological_process											owl:Class	
GO:0008846	biolink:NamedThing	obsolete endopeptidase La activity	OBSOLETE. Catalysis of the hydrolysis of large proteins such as globin, casein and denatured serum albumin, in presence of ATP.	tmpzr1t_l9r_go_relaxed.owl	ATP-dependent protease La activity|PIM1 protease activity|gene lon protease activity|protease La|gene lon proteins|ATP-dependent serine proteinase activity|Escherichia coli serine proteinase La|lon proteinase|PIM1 proteinase activity|endopeptidase La activity|ATP-dependent lon proteinase|proteinase La|serine protease La|Escherichia coli proteinase La			GO:0004252		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0017135	biolink:NamedThing	obsolete membrane-associated protein with guanylate kinase activity interacting	OBSOLETE. The interaction with synapse-associated membrane-associated protein with guanylate kinase activity.	tmpzr1t_l9r_go_relaxed.owl	membrane-associated protein with guanylate kinase activity interacting					This term was made obsolete because it does not represent a molecular function and the term name appears to make no sense.	GO:0019899				True			molecular_function											owl:Class	
GO:0006832	biolink:NamedThing	obsolete small molecule transport	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	small molecule transport					This term was made obsolete because it was an unnecessary grouping term.	GO:0006810				True			biological_process											owl:Class	
GO:0006918	biolink:NamedThing	obsolete induction of apoptosis by p53	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	induction of apoptosis by p53					This term was made obsolete because more accurate terms were created.	GO:0006915				True			biological_process											owl:Class	
GO:0045757	biolink:NamedThing	obsolete negative regulation of actin polymerization and/or depolymerization	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of actin polymerization and/or depolymerization.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of actin polymerization and/or depolymerization					This term was made obsolete because it has been split.	GO:0030835|GO:0030837				True			biological_process											owl:Class	
GO:0052540	biolink:NamedThing	obsolete positive regulation by organism of defense-related symbiont cell wall thickening	OBSOLETE. Any process by which an organism activates, maintains or increases the frequency, rate or extent of symbiont processes resulting in the thickening of its cell walls, occurring as part of the defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	positive regulation by organism of symbiont defensive cell wall thickening|positive regulation by organism of defense-related symbiont cell wall thickening					This term was made obsolete because it does not represent a real biological process.					True			biological_process											owl:Class	
GO:0098767	biolink:NamedThing	obsolete meiosis II M phase	OBSOLETE. M phase during meiosis II.	tmpzr1t_l9r_go_relaxed.owl						Obsoleted because added in error.	GO:0098762				True			biological_process											owl:Class	
GO:0052313	biolink:NamedThing	obsolete modulation of nutrient release from other organism involved in symbiotic interaction	OBSOLETE. Any process in which an organism modulates the frequency, rate or extent of the release of nutrients from a second organism, where the two organisms are in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	modulation of nutrient release from other organism during symbiotic interaction					This term was obsoleted because it represents an unnecessary grouping class.					True			biological_process											owl:Class	
OIO:hasNarrowSynonym	biolink:NamedThing	has_narrow_synonym		tmpzr1t_l9r_go_relaxed.owl																									owl:AnnotationProperty	
GO:0035957	biolink:NamedThing	obsolete positive regulation of starch catabolic process by positive regulation of transcription from RNA polymerase II promoter	OBSOLETE. Any process that activates or increases the frequency, rate or extent of the breakdown of starch, by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of starch degradation by regulation of transcription from Pol II promoter|positive regulation of starch catabolism by regulation of transcription from RNA polymerase II promoter|positive regulation of starch catabolism by regulation of transcription from Pol II promoter|positive regulation of starch degradation by regulation of transcription from RNA polymerase II promoter|positive regulation of starch catabolic process by regulation of transcription from Pol II promoter|positive regulation of starch breakdown by regulation of transcription from Pol II promoter|positive regulation of starch breakdown by regulation of transcription from RNA polymerase II promoter					This term was obsoleted because it represents a GO-CAM model.		bf			True			biological_process											owl:Class	
GO:0009367	biolink:NamedThing	obsolete prepilin peptidase complex	OBSOLETE. An enzyme complex that catalyzes the cleavage of a Gly-Phe bond to release an N-terminal, basic peptide of 5-8 residues from type IV prepilin, and then N-methylates the new N-terminal amino group.	tmpzr1t_l9r_go_relaxed.owl	prepilin peptidase complex					This term was made obsolete because prepilin peptidase is a single gene product, and there is no evidence that it acts as a multimer.					True			cellular_component											owl:Class	
GO:0045319	biolink:NamedThing	obsolete SRP-independent cotranslational protein-membrane targeting, translocation	OBSOLETE. The process during cotranslational membrane targeting wherein proteins move across a membrane. This process is independent of SRP and signal recognition.	tmpzr1t_l9r_go_relaxed.owl	SRP-independent cotranslational protein-membrane targeting, translocation|SRP-independent cotranslational membrane targeting, translocation					This term was made obsolete because there is no evidence for the existence of this process.					True			biological_process											owl:Class	
GO:0004927	biolink:NamedThing	obsolete sevenless receptor activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	sevenless receptor activity					This term was made obsolete because it represents a gene product rather than an activity.	GO:0004714|GO:0008288|GO:0004888				True			molecular_function											owl:Class	
GO:0017094	biolink:NamedThing	obsolete sterol regulatory element-binding protein site 1 protease activity	OBSOLETE. Catalysis of the cleavage of a Leu-Ser bond within the luminal loop of a sterol regulatory element binding protein (SREBP). This activity is the first of two sequential cleavage reactions and cleaves SREBP into two membrane-bound halves.	tmpzr1t_l9r_go_relaxed.owl	SREBP site 1 protease activity|sterol regulatory element-binding protein site 1 protease activity			GO:0008236		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:1900410	biolink:NamedThing	obsolete regulation of histone modification by regulation of transcription from RNA polymerase II promoter	OBSOLETE. A regulation of transcription from RNA polymerase II promoter that results in regulation of histone modification.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it describes a process that does not exist.		mah	2012-04-20T03:35:08Z		True			biological_process											owl:Class	
GO:0015096	biolink:NamedThing	obsolete manganese resistance permease activity	OBSOLETE. This term was not defined before being made obsolete.	tmpzr1t_l9r_go_relaxed.owl	manganese resistance permease activity					This term was made obsolete because the term is undefined and we don't know the mechanism so we can't make a correct definition.					True			molecular_function											owl:Class	
GO:1902588	biolink:NamedThing	obsolete multi-organism plasmodesmata-mediated intercellular transport	OBSOLETE. A plasmodesmata-mediated intercellular transport which involves another organism.	tmpzr1t_l9r_go_relaxed.owl	multi organism plasmodesmata-mediated intercellular transport					This term was obsoleted because there is no evidence that this process exists.		jl	2013-12-19T13:37:53Z		True			biological_process											owl:Class	
GO:1904945	biolink:NamedThing	obsolete response to cobalt(II) acetate	OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cobalt(II) acetate stimulus.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted at the TermGenie Gatekeeper stage.		mr	2016-02-02T16:47:52Z		True			biological_process											owl:Class	
GO:0008576	biolink:NamedThing	obsolete vesicle-fusing ATPase activity	OBSOLETE. Catalysis of the reaction: ATP + H2O = ADP + phosphate. The hydrolysis of ATP by an AAA-ATPase, involved in the heterotypic fusion of membrane vesicles with target membranes and the homotypic fusion of various membrane compartments.	tmpzr1t_l9r_go_relaxed.owl	vesicle-fusing ATPase activity			GO:0016887		This term was made obsolete because it incorporates process information.	GO:0016192|GO:0061025				True			molecular_function											owl:Class	
GO:1905160	biolink:NamedThing	obsolete positive regulation of Factor XII activation	OBSOLETE. Any process that activates or increases the frequency, rate or extent of Factor XII activation.	tmpzr1t_l9r_go_relaxed.owl	upregulation of Hageman factor activation|up regulation of Factor XII activation|up-regulation of Hageman factor activation|positive regulation of Hageman factor activation|up-regulation of Factor XII activation|activation of Hageman factor activation|activation of Factor XII activation|up regulation of Hageman factor activation|upregulation of Factor XII activation					This term was accidentally approved after TermGenie review.  It should not have been approved.		sl	2016-04-19T23:03:43Z		True			biological_process											owl:Class	
GO:0071778	biolink:NamedThing	obsolete WINAC complex	OBSOLETE. A SWI/SNF-type complex that directly interacts with the vitamin D receptor (VDR) through the Williams syndrome transcription factor (WSTF), and mediates the recruitment of unliganded VDR to VDR target sites in promoters. The WINAC complex contains at least 13 subunits, including WSTF, several SWI/SNF components, and DNA replication-related factors.	tmpzr1t_l9r_go_relaxed.owl	WINAC complex					This term was made obsolete because the paper describing the characterization of this complex, which was used to create this term, has been retracted.		mah	2010-08-31T12:19:54Z		True			cellular_component											owl:Class	
GO:0060796	biolink:NamedThing	obsolete regulation of transcription involved in primary germ layer cell fate commitment	OBSOLETE. Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that results in cells adopting an endoderm, ectoderm or mesoderm cell fate.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it represents a GO-CAM model.	GO:0060795|GO:0006357	dph	2009-08-04T03:40:21Z		True			biological_process											owl:Class	
GO:0018128	biolink:NamedThing	obsolete peptidyl-serine cyclase activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	peptidyl-serine cyclase activity				EC:4.2.1.-	This term was made obsolete because there is no record of why it was added, and no evidence can be found to suggest that this activity exists.					True			molecular_function											owl:Class	
GO:0010870	biolink:NamedThing	obsolete positive regulation of receptor biosynthetic process	OBSOLETE. Any process that increases the frequency or rate of receptor biosynthesis. Receptor biosynthesis is the collection of chemical reactions and pathways resulting in the formation of a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/19900				The reason for obsoletion is that those represent specific gene products, and genes annotated to those terms should be annotated to 'regulation of gene expression' or 'regulation of transcription' or some signaling term.					True			biological_process											owl:Class	
GO:0036095	biolink:NamedThing	obsolete positive regulation of invasive growth in response to glucose limitation by positive regulation of transcription from RNA polymerase II promoter	OBSOLETE. Any process that activates or increases the frequency, rate or extent of invasive growth as a result of deprivation of glucose, by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter.	tmpzr1t_l9r_go_relaxed.owl	transcriptional activation of genes involved in invasive growth					This term was obsoleted because it represents a GO-CAM model.		bf	2012-01-24T10:53:28Z		True			biological_process											owl:Class	
GO:0001307	biolink:NamedThing	obsolete extrachromosomal circular DNA accumulation involved in replicative cell aging	OBSOLETE. Increase in abundance of circular DNA molecules in dividing cells as they age. These molecules originate in the chromosome but are excised and circularized, often by intramolecular homologous recombination between direct tandem repeats, and then replicated independently of chromosomal replication.	tmpzr1t_l9r_go_relaxed.owl	extrachromosomal circular DNA accumulation during replicative cell ageing|extrachromosomal circular DNA accumulation during replicative cell aging	https://github.com/geneontology/go-ontology/issues/20007				This term was obsoleted because it represents an assay, not a true biological process.					True			biological_process											owl:Class	
GO:0008636	biolink:NamedThing	obsolete activation of caspase activity by protein phosphorylation	OBSOLETE. Upregulation of the activity of a caspase, a group of cysteine proteases involved in apoptosis, by the addition of a phosphate group.	tmpzr1t_l9r_go_relaxed.owl	caspase activation via phosphorylation|activation of caspase activity by protein amino acid phosphorylation|activation of caspase activity by protein phosphorylation					This term was made obsolete because it is ill-defined: phosphorylation regulates the activity of caspases, but it doesn't activate them (caspases are only activated upon cleavage).					True			biological_process											owl:Class	
GO:0007583	biolink:NamedThing	obsolete killer activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	killer activity					This term was made obsolete because it is ambiguous; 'killer activity' could refer to several different processes.	GO:0042267				True			biological_process											owl:Class	
GO:0052478	biolink:NamedThing	obsolete negative regulation by organism of defense-related symbiont cell wall callose deposition	OBSOLETE. Any process by which an organism stops, prevents, or reduces the frequency, rate or extent of the deposition of callose by the symbiont in its cell walls, occurring as part of the defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	negative regulation by organism of defense-related symbiont cell wall callose deposition					This term was made obsolete because it does not represent a valid biological process that occurs in nature.					True			biological_process											owl:Class	
GO:0045565	biolink:NamedThing	obsolete negative regulation of TRAIL receptor 1 biosynthetic process	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of TRAIL (TNF-related apoptosis inducing ligand) receptor 1.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of TRAIL receptor 1 synthesis|down-regulation of TRAIL receptor 1 biosynthetic process|negative regulation of TRAIL receptor 1 formation|inhibition of TRAIL receptor 1 biosynthetic process|downregulation of TRAIL receptor 1 biosynthetic process|negative regulation of TRAIL receptor 1 anabolism|negative regulation of TRAIL receptor 1 biosynthesis|down regulation of TRAIL receptor 1 biosynthetic process	https://github.com/geneontology/go-ontology/issues/19900				The reason for obsoletion is that those represent specific gene products, and genes annotated to those terms should be annotated to 'regulation of gene expression' or 'regulation of transcription' or some signaling term.					True			biological_process											owl:Class	
GO:0007336	biolink:NamedThing	obsolete bilateral process	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	bilateral process					This term was made obsolete because it gives no indication of what it refers to.					True			biological_process											owl:Class	
GO:0010546	biolink:NamedThing	obsolete Hsp90 protein inhibitor activity	OBSOLETE. Stops, prevents or reduces the activity of the Hsp90 molecular chaperone.	tmpzr1t_l9r_go_relaxed.owl	Hsp90 protein inhibitor activity			GO:0051879		This term was made obsolete because it refers to a non-existent molecular function term, 'Hsp90 protein activity'.	GO:0051787|GO:0006457|GO:0051082				True			molecular_function											owl:Class	
GO:0003800	biolink:NamedThing	obsolete antiviral response protein activity	OBSOLETE. A protein involved in an antiviral response.	tmpzr1t_l9r_go_relaxed.owl	antiviral response protein activity					This term was made obsolete because it refers to involvement in a biological process.	GO:0009615				True			molecular_function											owl:Class	
GO:0001168	biolink:NamedThing	obsolete transcription factor activity, RNA polymerase I upstream control element sequence-specific binding	OBSOLETE. Binding to a upstream control element (UCE, or alternately referred to as the upstream element, UE), a sequence of DNA that is in cis with and relatively close to a core promoter for RNA polymerase I in order to modulate transcription by RNA polymerase I.	tmpzr1t_l9r_go_relaxed.owl	RNA polymerase I upstream control element sequence-specific DNA binding transcription factor activity	https://github.com/geneontology/go-ontology/issues/15787				This term was obsoleted because it represents two separate functions. The corresponding 'binding' term should be used in combination with a transcription regulator activity child.		krc	2011-02-03T04:10:23Z		True			molecular_function											owl:Class	
GO:0001082	biolink:NamedThing	obsolete transcription factor activity, RNA polymerase I transcription factor binding	OBSOLETE. Binding to an RNA polymerase I transcription factor, which may be a single protein or a complex, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well.	tmpzr1t_l9r_go_relaxed.owl	RNA polymerase I transcription factor binding transcription factor activity					This term was obsoleted because it represents two separate functions. The corresponding 'binding' term should be used in combination with a transcription regulator activity child.		krc	2010-10-27T04:03:47Z		True			molecular_function											owl:Class	
GO:1901574	biolink:NamedThing	obsolete chemical substance biosynthetic process	OBSOLETE. The chemical reactions and pathways resulting in the formation of chemical substance.	tmpzr1t_l9r_go_relaxed.owl	chemical substance anabolism|chemical substance biosynthesis|chemical substance biosynthetic process|chemical substance formation|chemical substance synthesis					This term was obsoleted at the TermGenie Gatekeeper stage.		pr	2012-11-04T18:10:40Z		True			biological_process											owl:Class	
GO:0052113	biolink:NamedThing	obsolete adaptation to host osmotic environment	OBSOLETE. The responsive adjustment of an organism to the osmotic conditions in or around its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	adaptation to host osmotic environment|osmotic tolerance to host environment					This term was made obsolete because adaptation was not deemed to be a valid biological process.					True			biological_process											owl:Class	
GO:1903152	biolink:NamedThing	obsolete copper ion transmembrane transporter activity involved in copper ion import into cell	OBSOLETE. Any copper ion transmembrane transporter activity that is involved in copper ion import into cell.	tmpzr1t_l9r_go_relaxed.owl	intracellular copper ion transporter involved in copper cation import into cell|copper ion transmembrane transporter activity involved in copper cation import into cell|copper ion transmembrane transporter activity involved in copper ion import into cell|plasma membrane copper transporter involved in copper ion import into cell|plasma membrane copper transporter involved in copper cation import into cell|intracellular copper ion transporter involved in copper ion import into cell					This term was obsoleted at the TermGenie Gatekeeper stage.		dos	2014-07-09T11:55:47Z		True			molecular_function											owl:Class	
GO:0023054	biolink:NamedThing	obsolete signal initiation by stretch effect	OBSOLETE. The process in which a stretch signal causes activation of a receptor.	tmpzr1t_l9r_go_relaxed.owl	signal initiation by stretch effect					This term was made obsolete because the meaning of the term is ambiguous.	GO:0038023|GO:0007165		2010-02-16T09:30:50Z		True			biological_process											owl:Class	
GO:1900411	biolink:NamedThing	obsolete regulation of histone acetylation by regulation of transcription from RNA polymerase II promoter	OBSOLETE. A regulation of transcription from RNA polymerase II promoter that results in regulation of histone acetylation.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it describes a process that does not exist.		mah	2012-04-20T03:35:22Z		True			biological_process											owl:Class	
GO:0009478	biolink:NamedThing	obsolete cytochrome c554	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	cytochrome c554					This term was made obsolete because it represents a gene product.	GO:0009055				True			molecular_function											owl:Class	
GO:0075334	biolink:NamedThing	obsolete modulation of symbiont adenylate cyclase-mediated signal transduction in response to host	OBSOLETE. Any process in which the symbiont organism modulates the frequency, rate or extent of its adenylate cyclase-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/21740				This term was obsoleted because there is no evidence that this process exists.					True			biological_process											owl:Class	
GO:0009400	biolink:NamedThing	obsolete signal transducer, downstream of receptor, with serine/threonine phosphatase activity	OBSOLETE. Conveys a signal from an upstream receptor or intracellular signal transducer by catalysis of the reaction: protein serine phosphate + H2O = protein serine + phosphate, and protein threonine phosphate + H2O = protein threonine + phosphate.	tmpzr1t_l9r_go_relaxed.owl	receptor signaling protein serine/threonine phosphatase activity|receptor signalling protein serine/threonine phosphatase activity	https://github.com/geneontology/go-ontology/issues/14232				This term was obsoleted because it was not clearly defined.					True			molecular_function											owl:Class	
GO:0017063	biolink:NamedThing	obsolete phosphatidylserine-specific phospholipase A1 activity	OBSOLETE. Catalysis of the reaction: phosphatidylcholine + H2O = 2-acylglycerophosphocholine + a fatty acid anion.	tmpzr1t_l9r_go_relaxed.owl	phosphatidylserine-specific phospholipase A1 activity					This term was made obsolete because the definition does not match the term name.	GO:0052740|GO:0052739				True			molecular_function											owl:Class	
GO:0006135	biolink:NamedThing	obsolete dihydropteridine reduction	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	dihydropteridine reduction					This term was made obsolete because it represents a molecular function rather than a biological process.	GO:0051067|GO:0004155|GO:0022900				True			biological_process											owl:Class	
GO:0046791	biolink:NamedThing	obsolete suppression by virus of host complement neutralization	OBSOLETE. Any viral process that results in the inhibition of complement neutralization of the host cell.	tmpzr1t_l9r_go_relaxed.owl	negative regulation by virus of host complement neutralization|suppression by virus of host complement neutralization					This term was made obsolete because the meaning of the term is unclear. It most likely refers to inhibiting the process by which a virus particle is neutralized by the host cell in a complement-dependent manner.					True			biological_process											owl:Class	
GO:0051846	biolink:NamedThing	obsolete active evasion of symbiont immune response	OBSOLETE. Any mechanism of immune avoidance that directly affects the symbiont immune system, e.g. blocking any stage in symbiont MHC class I and II presentation. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	active evasion of symbiont immune response|active immune evasion					This term was made obsolete because it does not represent a real process that exists in nature.					True			biological_process											owl:Class	
GO:0015534	biolink:NamedThing	obsolete proline/glycine/betaine:hydrogen/sodium symporter activity	OBSOLETE. Catalysis of the reaction: (proline, glycine or betaine)(out) + (H+ or Na+)(out) = (proline, glycine or betaine)(in) + (H+ or Na+)(in).	tmpzr1t_l9r_go_relaxed.owl	proline/glycine/betaine:hydrogen/sodium symporter activity|proline/glycine/betaine:proton/sodium symporter					This term was made obsolete because it represents a multifunctional gene product.	GO:0015187|GO:0015370|GO:0015295|GO:0015193|GO:0015199|GO:0015294				True			molecular_function											owl:Class	
GO:0030088	biolink:NamedThing	obsolete PSII associated light-harvesting complex II, core complex, LHCIId subcomplex	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	PSII associated light-harvesting complex II, core complex, LHCIId subcomplex			GO:0009655		This term was made obsolete because the 'complex' it refers to contains only one gene product.					True			cellular_component											owl:Class	
GO:1990445	biolink:NamedThing	obsolete Multiciliate cell differentiation	OBSOLETE. The process in which a relatively unspecialized cell acquires features of a multiciliated cell, a specialized epithelial cell type that extends anywhere from 150 to 200 motile cilia per cell in order to produce a vigorous fluid flow critical to human health in several organ systems.	tmpzr1t_l9r_go_relaxed.owl	Multiciliate cell differentiation					This term was obsoleted at the TermGenie Gatekeeper stage.		sp	2014-08-05T14:31:28Z		True			biological_process											owl:Class	
GO:0005193	biolink:NamedThing	obsolete major urinary protein	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	major urinary protein					This term was made obsolete because it describes presence in body fluids rather than an activity.					True			molecular_function											owl:Class	
GO:0043745	biolink:NamedThing	obsolete N2-acetyl-L-aminoadipate semialdehyde dehydrogenase activity	OBSOLETE. Catalysis of the reaction: N2-acetyl-L-aminoadipyl-delta-phosphate + NADPH + H+ = N2-acetyl-L-aminoadipate semialdehyde + NADP+ + orthophosphate.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/18908				This term was obsoleted because there is no evidence that it exists.					True			molecular_function											owl:Class	
GO:0005625	biolink:NamedThing	obsolete soluble fraction	OBSOLETE. That fraction of cells, prepared by disruptive biochemical methods, that is soluble in water.	tmpzr1t_l9r_go_relaxed.owl	soluble fraction|soluble					This term was made obsolete because it refers to a cell fractionation experimental result and not a bona fide cellular component.	GO:0005575				True			cellular_component											owl:Class	
GO:0046303	biolink:NamedThing	obsolete 2-nitropropane biosynthetic process	OBSOLETE. The chemical reactions and pathways resulting in the formation of 2-nitropropane, a clear, colorless liquid with a mild, fruity odor.	tmpzr1t_l9r_go_relaxed.owl	2-nitropropane synthesis|2-nitropropane formation|2-nitropropane biosynthetic process|2-nitropropane anabolism|2-nitropropane biosynthesis			GO:0018938		This term was made obsolete because 2-nitropropane is not synthesized by living organisms, and GO does not cover non-biological processes.					True			biological_process											owl:Class	
GO:0075236	biolink:NamedThing	obsolete positive regulation of zoospore movement on or near host	OBSOLETE. Any process that activates, maintains or increases the frequency, rate or extent of zoospore movement on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it represented both a process and a location.					True			biological_process											owl:Class	
GO:0006988	biolink:NamedThing	obsolete unfolded protein response, cleavage of primary transcript encoding UFP-specific transcription factor	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	unfolded protein response, cleavage of primary transcript encoding UFP-specific transcription factor					This term was made obsolete because it represents a function rather than a process.	GO:0004521				True			biological_process											owl:Class	
GO:0016834	biolink:NamedThing	obsolete other carbon-carbon lyase activity	OBSOLETE. A grouping term for carbon-carbon lyases that cannot be more accurately categorized.	tmpzr1t_l9r_go_relaxed.owl	other carbon-carbon lyase activity					This term was made obsolete because it was an unnecessary grouping term.	GO:0016830				True			molecular_function											owl:Class	
GO:0031608	biolink:NamedThing	obsolete ER proteasome core complex, beta-subunit complex	OBSOLETE. The subunits forming the inner ring of the core complex of a proteasome located in the endoplasmic reticulum of a cell.	tmpzr1t_l9r_go_relaxed.owl						This term was made obsolete because there is no evidence in the literature of its existence.					True			cellular_component											owl:Class	
GO:0015522	biolink:NamedThing	obsolete hydrophobic uncoupler:proton antiporter activity	OBSOLETE. Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: hydrophobic uncoupler(in) + H+(out) = hydrophobic uncoupler(out) + H+(in). Hydrophobic uncouplers include CCCP, benzalkonium and SDS.	tmpzr1t_l9r_go_relaxed.owl	hydrophobic uncoupler:hydrogen antiporter activity					The reason for obsoletion is that this term represented a specific protein in TCDB, 2.A.1.2.9, which actually is a sugar transporter that seems to also function as a multidrug efflux protein.					True			molecular_function											owl:Class	
GO:0000203	biolink:NamedThing	obsolete activation of MAPKKK during sporulation (sensu Saccharomyces)	OBSOLETE. Upregulation of MAPKKK activity in the context of sporulation. As in, but not restricted to, the taxon Saccharomyces (Saccharomyces, ncbi_taxonomy_id:4930).	tmpzr1t_l9r_go_relaxed.owl	activation of MAPKKK during sporulation (sensu Saccharomyces)					This term was made obsolete because it is a gene product specific term.					True			biological_process											owl:Class	
GO:0062198	biolink:NamedThing	obsolete rDNA replication pause site heterochromatin	OBSOLETE. A region of heterochromatin associated with sites in rDNA repeats where replication forks pause.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/19178				This term was obsoleted because it does not represent a specific cellular component.		dph	2019-12-11T20:32:24Z		True			cellular_component											owl:Class	
GO:0019132	biolink:NamedThing	obsolete C-terminal processing peptidase activity	OBSOLETE. Catalysis of the cleavage of peptides after specific recognition of a C-terminal tripeptide, Xaa-Yaa-Zaa, in which Xaa is preferably Ala or Leu, Yaa is preferably Ala or Tyr, and Zaa is preferably Ala. Cleavage is at a variable distance from the C-terminus; a typical cleavage is -Ala-Ala-Arg-Ala-Ala-Lys-Glu-Asn-Tyr-Ala-Leu-Ala-Ala.	tmpzr1t_l9r_go_relaxed.owl	tail-specific protease activity|photosystem II D1 protein processing peptidase|C-terminal processing peptidase activity|Tsp protease|protease Re|CtpA gene product (Synechocystis sp.)			GO:0004252		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0023012	biolink:NamedThing	obsolete initiation of T cell receptor signaling by binding of a MHC complex to T cell receptor	OBSOLETE. The process in which binding of an MHC complex to T cell receptor causes activation of T cell receptor signaling.	tmpzr1t_l9r_go_relaxed.owl	initiation of T cell receptor signalling by binding of a MHC complex to T cell receptor|initiation of T cell receptor signaling by binding of a MHC complex to T cell receptor					This term was made obsolete because it is describing a binding molecular function.	GO:0050852|GO:0042101		2010-02-16T09:30:50Z		True			biological_process											owl:Class	
OIO:source	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl																									owl:AnnotationProperty	
GO:0009457	biolink:NamedThing	obsolete flavodoxin	OBSOLETE. A group of small electron carriers, characteristic of anaerobic bacteria, photosynthetic bacteria, cyanobacteria and eukaryotic algae. Contain flavin mononucleotide.	tmpzr1t_l9r_go_relaxed.owl	flavodoxin			GO:0009055		This term was made obsolete because it represents a class of gene products.					True			molecular_function											owl:Class	
GO:0044216	biolink:NamedThing	obsolete other organism cell	OBSOLETE. A cell of a secondary organism with which the first organism is interacting.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/19036|https://github.com/geneontology/go-ontology/issues/17394				This term was obsoleted because cell (and therefore 'other organism cell') was considered outside the scope of GO.		jl	2009-11-12T01:17:06Z		True			cellular_component											owl:Class	
GO:1990815	biolink:NamedThing	obsolete regulation of protein localization to cell division site after cytokinesis	OBSOLETE. Any process that modulates the frequency, rate or extent of protein localization to cell division site involved in cell separation after cytokinesis.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted at the TermGenie Gatekeeper stage.		vw	2015-07-29T14:03:34Z		True			biological_process											owl:Class	
GO:0052420	biolink:NamedThing	obsolete metabolism by host of symbiont xylan	OBSOLETE. The chemical reactions and pathways performed by an organism involving xylan within the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/21396				This term was obsoleted because there is no evidence it exists.					True			biological_process											owl:Class	
GO:0019040	biolink:NamedThing	obsolete viral host shutoff protein	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	viral host shutoff protein					This term was made obsolete because it does not represent a molecular function.	GO:0004534|GO:0019057				True			molecular_function											owl:Class	
GO:0016986	biolink:NamedThing	obsolete transcription initiation factor activity	OBSOLETE. Plays a role in regulating transcription initiation.	tmpzr1t_l9r_go_relaxed.owl	transcriptional initiation factor activity|transcription initiation factor activity					This term was obsoleted because it is essentially identical to a Process term (specifically the Biological Process term which has been selected as a term to consider for reannotation), i.e. it is defined only in terms of the process it acts in and it does NOT convey any information about the molecular nature of the function or whether the function is based on binding DNA, on interacting with other proteins, or some other mechanism. To transfer all annotations without review, the BP term indicated is considered to be equivalent and thus the only appropriate destination for all annotations. To reannotate to a MF term, you will probably need to revisit the original literature or other primary data because this "MF" term was not defined in terms of mechanism of action and there are multiple possibilities in the revised MF structure. In reannotation, please also consider descendent terms of the suggested MF terms as a more specific term may be more appropriate than the MF terms indicated. Please be aware that you may wish to request a new term if the mechanism of action of this gene product is not yet represented or if you are annotating for an RNAP different than one for which there is a specific suggested term. Also note that if there is no information about how the gene product acts, it may be appropriate to annotate to the root term for molecular_function.	GO:0140223				True			molecular_function											owl:Class	
GO:0001753	biolink:NamedThing	obsolete adult eye photoreceptor development (sensu Drosophila)	OBSOLETE. Development of a photoreceptor, a receptor that responds to light, in the adult Drosophila eye.	tmpzr1t_l9r_go_relaxed.owl	adult eye photoreceptor development (sensu Drosophila)					This term was made obsolete because eye photoreceptors have completed their development by the time the adult phase begins.	GO:0042051				True			biological_process											owl:Class	
GO:0016355	biolink:NamedThing	obsolete DDT susceptibility/resistance	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	DDT susceptibility/resistance			GO:0046680		This term was made obsolete because 'resistance' implies a phenotype rather than a biological process.					True			biological_process											owl:Class	
GO:0075165	biolink:NamedThing	obsolete regulation of G-protein gamma subunit-mediated signal transduction in response to host	OBSOLETE. Any process in which the symbiont organism modulates the frequency, rate or extent of its G-protein gamma subunit-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	regulation of symbiont G-protein gamma subunit-mediated signal transduction in response to host					This term was obsoleted because there is no evidence that this process exists.					True			biological_process											owl:Class	
GO:0047944	biolink:NamedThing	obsolete glutamate 1-kinase activity	OBSOLETE. Catalysis of the reaction: L-glutamate + ATP = alpha-L-glutamyl phosphate + ADP + H(+).	tmpzr1t_l9r_go_relaxed.owl	ATP:L-glutamate 1-phosphotransferase activity					This term is slated for obsoletion. RHEA indicates the activity has been shown not to exist.					True			molecular_function											owl:Class	
GO:1900524	biolink:NamedThing	obsolete positive regulation of flocculation via cell wall protein-carbohydrate interaction by positive regulation of transcription from RNA polymerase II promoter	OBSOLETE. Any process that activates or increases the frequency, rate or extent of flocculation via cell wall protein-carbohydrate interaction process by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter.	tmpzr1t_l9r_go_relaxed.owl	upregulation of flocculation via cell wall protein-carbohydrate interaction by positive regulation of transcription from RNA polymerase II promoter|activation of flocculation via cell wall protein-carbohydrate interaction by positive regulation of transcription from RNA polymerase II promoter|up regulation of flocculation via cell wall protein-carbohydrate interaction by positive regulation of transcription from RNA polymerase II promoter|up-regulation of flocculation via cell wall protein-carbohydrate interaction by positive regulation of transcription from RNA polymerase II promoter					This term was obsoleted because it represents a GO-CAM.		dgf	2012-05-03T05:13:41Z		True			biological_process											owl:Class	
GO:0052106	biolink:NamedThing	obsolete quorum sensing involved in interaction with host	OBSOLETE. The process in which a community of single-celled organisms living in intimate contact with a host organism monitors population density by detecting the concentration of small diffusible signal molecules. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	quorum sensing during interaction with host					The reason for obsoletion is that this term was not clearly defined and usage was inconsistent.					True			biological_process											owl:Class	
GO:0052221	biolink:NamedThing	obsolete positive chemotaxis in environment of other organism involved in symbiotic interaction	OBSOLETE. The directed movement of a motile cell or organism towards a higher concentration of a chemical on, within or near a second organism, where the two organisms are in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	positive chemotaxis in response to environment of other organism|positive chemotaxis in environment of other organism during symbiotic interaction	https://github.com/geneontology/go-ontology/issues/18819				This term was obsoleted because it represents both a process and a location.					True			biological_process											owl:Class	
GO:0030489	biolink:NamedThing	obsolete processing of 27S pre-rRNA	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	processing of 27S pre-rRNA					This term was made obsolete because it was not defined and did not correspond to the production of a single specific mature rRNA product.					True			biological_process											owl:Class	
GO:0004286	biolink:NamedThing	obsolete proprotein convertase 2 activity	OBSOLETE. Catalysis of the release of protein hormones and neuropeptides from their precursors, generally by cleavage of -Lys-Arg-Xaa at the Arg-Xaa bond.	tmpzr1t_l9r_go_relaxed.owl	NEC 2 activity|PC2 activity|prohormone convertase II activity|neuroendocrine convertase 2 activity|proprotein convertase 2 activity			GO:0004252		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0015358	biolink:NamedThing	obsolete amino acid/choline transmembrane transporter activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	amino acid/choline transmembrane transporter activity					This term was made obsolete because it represents a multifunctional gene product.	GO:0015220|GO:0015171				True			molecular_function											owl:Class	
GO:0052122	biolink:NamedThing	obsolete negative aerotaxis in host environment	OBSOLETE. The directed movement of a motile cell or organism towards a lower concentration of environmental oxygen on, within or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	negative aerotaxis in response to host environment	https://github.com/geneontology/go-ontology/issues/18819				This term was obsoleted because it represents both a process and a location.					True			biological_process											owl:Class	
GO:0004007	biolink:NamedThing	obsolete heavy metal-exporting ATPase activity	OBSOLETE. Catalysis of the reaction: heavy metal ion(in) + ATP + H2O = heavy metal ion(out) + ADP + phosphate.	tmpzr1t_l9r_go_relaxed.owl	heavy metal-exporting ATPase activity					This term was made obsolete because 'heavy metal' is an ambiguous grouping term which has no set meaning (see Pure Appl. Chem. Vol. 74, No. 5, pp. 793-807, 2002, for more information).	GO:0046873				True			molecular_function											owl:Class	
GO:0003080	biolink:NamedThing	obsolete negative regulation of natriuresis	OBSOLETE. Any process that stops, prevents, or decreases the frequency, rate, or extent of natriuresis, the process of renal sodium excretion.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of natriuresis					This term was made obsolete because its definition was inaccurate.	GO:0035814				True			biological_process											owl:Class	
GO:0005627	biolink:NamedThing	obsolete ascus	OBSOLETE. A sac-like fruiting body (ascomycete Fungi); contains ascospores (typically eight in number).	tmpzr1t_l9r_go_relaxed.owl	ascus					This term was made obsolete because it is a structure that contains cell (ascospores) rather than a cellular component. To update annotations, consider the external ontology term 'ascus ; FAO:0000014'.					True			cellular_component											owl:Class	
GO:0004262	biolink:NamedThing	obsolete cerevisin activity	OBSOLETE. Catalysis of the hydrolysis of proteins with broad specificity, and of BZ-Arg-OET > Ac-Tyr-OET. Does not hydrolyze peptide amides.	tmpzr1t_l9r_go_relaxed.owl	baker's yeast proteinase B|peptidase beta|brewer's yeast proteinase|cerevisin activity|proteinase yscB activity|yeast proteinase B activity			GO:0004252		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0003378	biolink:NamedThing	obsolete regulation of inflammatory response by sphingosine-1-phosphate signaling pathway	OBSOLETE. A sphingosine-1-phosphate signaling pathway that modulates the rate, frequency, or extent of the inflammatory response.	tmpzr1t_l9r_go_relaxed.owl	regulation of inflammatory response by sphingolipid signaling pathway|regulation of inflammatory response by sphingolipid signalling pathway					The reason for obsoletion is that this term represents a GO-CAM model.		dph	2009-12-09T06:38:06Z		True			biological_process											owl:Class	
GO:0004986	biolink:NamedThing	obsolete delta-opioid receptor activity	OBSOLETE. Combining with an opioid to initiate a change in cell activity, with the pharmacological characteristics of delta-opioid receptors, including the activity of enkephalins as ligands.	tmpzr1t_l9r_go_relaxed.owl	delta-opioid receptor activity				Wikipedia:Delta_Opioid_receptor	This term was made obsolete because the receptor is defined based on its pharmacological properties.	GO:0038046				True			molecular_function											owl:Class	
GO:0045100	biolink:NamedThing	obsolete desmin	OBSOLETE. A type of intermediate filament.	tmpzr1t_l9r_go_relaxed.owl	desmin					This term was made obsolete because it represents a gene product.	GO:0045098				True			cellular_component											owl:Class	
GO:0050466	biolink:NamedThing	obsolete oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond, with other acceptors	OBSOLETE. Catalysis of an oxidation-reduction (redox) reaction in which X-H and Y-H form X-Y and the acceptor is not disulfide or oxygen.	tmpzr1t_l9r_go_relaxed.owl	oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond, with other acceptors					This term was made obsolete because it was an unnecessary grouping term.	GO:0046992				True			molecular_function											owl:Class	
GO:0036097	biolink:NamedThing	obsolete pre-miRNA 3'-end processing	OBSOLETE. Any process involved in forming the mature 3' end of a miRNA from a pre-miRNA.	tmpzr1t_l9r_go_relaxed.owl	miRNA 3'-end processing|pre-miRNA 3'-end processing|microRNA 3'-end processing					This term was made obsolete because it is not real a process, and was created accidentally.		bf	2012-01-24T02:31:37Z		True			biological_process											owl:Class	
GO:0060154	biolink:NamedThing	obsolete cellular process regulating host cell cycle in response to virus	OBSOLETE. Any cellular process that modulates the rate or extent of progression through the cell cycle in response to a virus.	tmpzr1t_l9r_go_relaxed.owl						The reason for obsoletion is that based on the definition, it is not clear that this process exists.					True			biological_process											owl:Class	
GO:0045096	biolink:NamedThing	obsolete acidic keratin	OBSOLETE. A type of intermediate filament.	tmpzr1t_l9r_go_relaxed.owl	type I intermediate filament|acidic keratin			GO:0045095		This term was made obsolete because it represents a gene product.					True			cellular_component											owl:Class	
GO:0051398	biolink:NamedThing	obsolete N-terminal lysine aminopeptidase activity	OBSOLETE. Catalysis of the hydrolysis of a lysine residue from the N-terminal of an oligopeptide or polypeptide chain.	tmpzr1t_l9r_go_relaxed.owl	lysine aminopeptidase activity|lysyl aminopeptidase activity|N-terminal lysine aminopeptidase activity			GO:0004177		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0016883	biolink:NamedThing	obsolete other carbon-nitrogen ligase activity	OBSOLETE. A grouping term for carbon-nitrogen ligases that cannot be more accurately categorized.	tmpzr1t_l9r_go_relaxed.owl	other carbon-nitrogen ligase activity					This term was made obsolete because it was an unnecessary grouping term.	GO:0016879				True			molecular_function											owl:Class	
GO:0005569	biolink:NamedThing	obsolete small nucleolar RNA	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	small nucleolar RNA					This term was made obsolete because it represents gene products.	GO:0030555				True			molecular_function											owl:Class	
GO:0010869	biolink:NamedThing	obsolete regulation of receptor biosynthetic process	OBSOLETE. Any process that modulates the frequency or rate of receptor biosynthesis. Receptor biosynthesis is the collection of chemical reactions and pathways resulting in the formation of a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/19900				The reason for obsoletion is that those represent specific gene products, and genes annotated to those terms should be annotated to 'regulation of gene expression' or 'regulation of transcription' or some signaling term.					True			biological_process											owl:Class	
GO:0072369	biolink:NamedThing	obsolete regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter	OBSOLETE. Any process that modulates the frequency, rate or extent of lipid transport by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter.	tmpzr1t_l9r_go_relaxed.owl	regulation of lipid transport by positive regulation of transcription from an RNA polymerase II promoter					This term was obsoleted because it represents a GO-CAM model.		mah	2010-11-16T03:23:53Z		True			biological_process											owl:Class	
GO:0061427	biolink:NamedThing	obsolete negative regulation of ceramide biosynthetic process by negative regulation of transcription from RNA Polymerase II promoter	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of transcription from an RNA polymerase II promoter and stops, prevents or reduces the frequency, rate or extent of a ceramide biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it represents a GO-CAM model.		dph	2012-02-02T01:30:41Z		True			biological_process											owl:Class	
GO:0005580	biolink:NamedThing	obsolete membrane attack complex protein alphaM chain	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	membrane attack complex protein alphaM chain			GO:0005579		This term was made obsolete because it represents a single gene product and not a complex.					True			cellular_component											owl:Class	
GO:0070438	biolink:NamedThing	obsolete mTOR-FKBP12-rapamycin complex	OBSOLETE. A protein complex that contains the mTOR (mammalian target of rapamycin) serine/threonine kinase, the peptidyl-prolyl cis-trans isomerase FKBP12 (FKBP1A) and rapamycin (sirolimus).	tmpzr1t_l9r_go_relaxed.owl	Fkbp1a-Frap1 complex|mTOR-FKBP12-rapamycin complex					This term was made obsolete because it describes a complex with a drug bound, with the drug being exogenous to the species where the experiment takes place and where that interaction would never occur naturally.					True			cellular_component											owl:Class	
GO:0052361	biolink:NamedThing	obsolete catabolism by organism of macromolecule in other organism involved in symbiotic interaction	OBSOLETE. The chemical reactions and pathways performed by an organism resulting in the breakdown of macromolecules within a second organism, where the two organisms are in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	catabolism by organism of macromolecule in other organism during symbiotic interaction	https://github.com/geneontology/go-ontology/issues/21396				This term was obsoleted because it represents an unnecessary grouping class.					True			biological_process											owl:Class	
GO:0006200	biolink:NamedThing	obsolete ATP catabolic process	OBSOLETE. The chemical reactions and pathways resulting in the breakdown of ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.	tmpzr1t_l9r_go_relaxed.owl	ATP hydrolysis|ATP breakdown|ATP catabolism|ATP degradation				Wikipedia:ATP_hydrolysis	The reason for making this term obsolete is that it gets misused in cases where phosphates are simply being removed from a small molecule. We found no cases where these molecules genuinely underwent catabolism.	GO:0016887				True			biological_process											owl:Class	
GO:0043156	biolink:NamedThing	obsolete chromatin remodeling in response to cation stress	OBSOLETE. Structural changes to eukaryotic chromatin occurring as a result of cation stress, an increase or decrease in the concentration of positively charged ions in the environment.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/22036				This term was obsoleted because it represents a GO-CAM model.					True			biological_process											owl:Class	
GO:0008565	biolink:NamedThing	obsolete protein transporter activity	OBSOLETE. Enables the directed movement of proteins into, out of or within a cell, or between cells.	tmpzr1t_l9r_go_relaxed.owl	enzyme transporter activity|secretin|holin|protein transport chaperone					This term was obsoleted because is has been inconsistently used.					True			molecular_function											owl:Class	
GO:0044046	biolink:NamedThing	obsolete interaction with host via substance released outside of symbiont	OBSOLETE. An interaction with the host organism mediated by a substance that is released by the other organism. This includes substances that are released via pathogen cell lysis.	tmpzr1t_l9r_go_relaxed.owl	interaction with host via substance released outside of symbiont cells					This term was obsoleted because it conflates a process and the mechanism of secretion of the gene product mediating the process.					True			biological_process											owl:Class	
GO:0022866	biolink:NamedThing	obsolete transmembrane 1-electron transfer carrier	OBSOLETE. Enables transfer of one electron across a membrane.	tmpzr1t_l9r_go_relaxed.owl	transmembrane one-electron transfer carrier					The reason for obsoletion is that the term does not represent a molecular function but rather a process.					True			molecular_function											owl:Class	
GO:0048310	biolink:NamedThing	obsolete nucleus inheritance	OBSOLETE. The partitioning of nuclei between daughter cells at cell division.	tmpzr1t_l9r_go_relaxed.owl	cell nucleus inheritance					This term was obsoleted because it was not clearly defined.					True			biological_process											owl:Class	
GO:0035110	biolink:NamedThing	obsolete leg morphogenesis	OBSOLETE. The process in which the anatomical structures of a leg are generated and organized. A leg is a limb on which an animal walks and stands.	tmpzr1t_l9r_go_relaxed.owl	leg morphogenesis					This term was made obsolete because leg is a mechano-functional grouping, and having both 'leg morphogenesis' and 'hindlimb morphogenesis' terms causes errors in querying.	GO:0035137|GO:0035108|GO:0007480				True			biological_process											owl:Class	
GO:1902401	biolink:NamedThing	obsolete detection of stimulus involved in mitotic DNA damage checkpoint	OBSOLETE. Any detection of stimulus that is involved in mitotic DNA damage checkpoint.	tmpzr1t_l9r_go_relaxed.owl	stimulus sensing involved in mitotic DNA damage checkpoint|stimulus detection involved in mitotic DNA damage checkpoint|perception of stimulus involved in mitotic DNA damage checkpoint	https://github.com/geneontology/go-ontology/issues/20976				This term was obsoleted because it corresponds to a molecular function.		jl	2013-09-12T12:07:12Z		True			biological_process											owl:Class	
GO:0045195	biolink:NamedThing	obsolete gallstone formation	OBSOLETE. The formation of gallstones, hard, crystal-like accretions of cholesterol and bile pigments which develop when bile contains too much cholesterol and not enough bile.	tmpzr1t_l9r_go_relaxed.owl	gallstone formation					This term was made obsolete because the process it represents is pathological.					True			biological_process											owl:Class	
GO:0033751	biolink:NamedThing	obsolete linoleate 8R-lipoxygenase	OBSOLETE. Catalysis of the reaction: linoleate + O2 = (9Z,12Z)-(7S,8S)-dihydroxyoctadeca-9,12-dienoate.	tmpzr1t_l9r_go_relaxed.owl	5,8-linoleate diol synthase (bifunctional enzyme)|7,8-linoleate diol synthase (bifunctional enzyme)|linoleate diol synthase activity					The reason for obsoletion is because there is no support for the reaction. EC and RHEA mappings have been obsoleted at  their source.					True			molecular_function											owl:Class	
GO:0048153	biolink:NamedThing	obsolete S100 alpha biosynthetic process	OBSOLETE. The chemical reactions and pathways resulting in the formation of S100 alpha protein. S100 is a small calcium and zinc binding protein produced in astrocytes that is implicated in Alzheimer's disease, Down Syndrome and ALS.	tmpzr1t_l9r_go_relaxed.owl	S100 alpha anabolism|S100 alpha formation|S100 alpha synthesis|S100 alpha biosynthesis	https://github.com/geneontology/go-ontology/issues/19900				The reason for obsoletion is that those represent specific gene products, and genes annotated to those terms should be annotated to 'regulation of gene expression' or 'regulation of transcription' or some signaling term.					True			biological_process											owl:Class	
GO:0106181	biolink:NamedThing	obsolete translocase activity acting on inorganic anions	OBSOLETE. Catalysis of the translocation of inorganic anions.	tmpzr1t_l9r_go_relaxed.owl					EC:7.3.-.-	This term was made obsolete because the concept of using the non-4 digit EC classes as parent terms for the transporter banch of the onotolgy was consided confusing.		hjd	2019-04-05T15:50:54Z		True			molecular_function											owl:Class	
GO:0050987	biolink:NamedThing	obsolete enzyme active site formation via O-sulfo-L-serine	OBSOLETE. The transient sulfation of peptidyl-serine to form O-sulfo-L-serine.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/15594			RESID:AA0361	This term was obsoleted because it was created by error: O-sulfo-L-serine is a post-translational modification, see PMID:14752058.					True			biological_process											owl:Class	
GO:0009481	biolink:NamedThing	obsolete aa3-type cytochrome c oxidase	OBSOLETE. Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: 4 ferrocytochrome c + O2 = 4 ferricytochrome c + 2 H2O.	tmpzr1t_l9r_go_relaxed.owl	aa3-type cytochrome c oxidase			GO:0004129		This term was made obsolete because it describes a class of gene products rather than a molecular function.					True			molecular_function											owl:Class	
GO:0052231	biolink:NamedThing	obsolete modulation of phagocytosis in other organism involved in symbiotic interaction	OBSOLETE. Any process in which an organism modulates the frequency, rate or extent of phagocytosis, the engulfing by phagocytes of external particulate material, in a second organism, where the two organisms are in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	modulation of phagocytosis in other organism during symbiotic interaction	https://github.com/geneontology/go-ontology/issues/18562				This term was obsoleted because there is no evidence that this process exists.					True			biological_process											owl:Class	
GO:0090047	biolink:NamedThing	obsolete positive regulation of transcription regulator activity	OBSOLETE. Any process that increases the frequency, rate or extent of transcription regulator activity, any molecular function that plays a role in regulating transcription; may bind a promoter or enhancer DNA sequence or interact with a DNA-binding transcription factor.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of transcription regulator activity					At the time of obsoletion, under "regulation of molecular function", a term exists for "regulation of sequence-specific DNA-binding transcription factor activity" and the positive and negative child terms, but no more detailed terms exist. In reannotating, please consider if the paper would support annotation to a regulation term for a specific RNA polymerase. Also consider if what you need would be regulation of protein binding transcription factor activity or any of its child terms instead. If so, please consider making a SF item regarding creation of such a term.		tb	2009-08-07T10:24:24Z		True			biological_process											owl:Class	
GO:0072365	biolink:NamedThing	obsolete regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter	OBSOLETE. Any process that modulates the frequency, rate or extent of a cellular ketone metabolic process by stopping, preventing, or reducing the frequency, rate or extent of transcription from an RNA polymerase II promoter.	tmpzr1t_l9r_go_relaxed.owl	regulation of cellular ketone metabolism by negative regulation of transcription from an RNA polymerase II promoter|regulation of cellular ketone metabolic process by negative regulation of transcription from an RNA polymerase II promoter					This term was obsoleted because it represents a GO-CAM model.		mah	2010-11-16T03:12:09Z		True			biological_process											owl:Class	
GO:2000682	biolink:NamedThing	obsolete positive regulation of rubidium ion transport	OBSOLETE. Any process that activates or increases the frequency, rate or extent of rubidium ion transport.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of Rb+ transport|positive regulation of rubidium cation transport					This term has been obsoleted because it represents an assay, and not a physiological process.		bf	2011-05-10T10:54:37Z		True			biological_process											owl:Class	
GO:0001308	biolink:NamedThing	obsolete negative regulation of chromatin silencing involved in replicative cell aging	OBSOLETE. The process, which occurs as a dividing cell ages, leading to expression of genes that are typically not expressed due to silencing by regulatory proteins.	tmpzr1t_l9r_go_relaxed.owl	loss of chromatin silencing involved in replicative cell aging|loss of chromatin silencing during replicative cell ageing	https://github.com/geneontology/go-ontology/issues/20007				This term was obsoleted because it represents an assay, not a true biological process.					True			biological_process											owl:Class	
GO:0033236	biolink:NamedThing	obsolete 11-beta-hydroxysteroid dehydrogenase (NAD+) activity	OBSOLETE. Catalysis of the reaction: an 11-beta-hydroxysteroid + NAD+ = an 11-oxosteroid + NADH + H+.	tmpzr1t_l9r_go_relaxed.owl	11-beta-hydroxysteroid dehydrogenase (NAD+) activity			GO:0070523							True			molecular_function											owl:Class	
GO:0016902	biolink:NamedThing	obsolete oxidoreductase activity, acting on the CH-OH group of donors, other acceptors	OBSOLETE. Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces an acceptor other than a cytochrome, disulfide, NAD, NADP, oxygen or a quinone or similar compound.	tmpzr1t_l9r_go_relaxed.owl	oxidoreductase activity, acting on the CH-OH group of donors, other acceptors					This term was made obsolete because it was an unnecessary grouping term.	GO:0016614				True			molecular_function											owl:Class	
GO:0009936	biolink:NamedThing	obsolete expansin	OBSOLETE. A group of proteins located within the cell walls of plants, both dicots and grasses, that play an essential role in loosening cell walls during cell growth. They are hydrophobic, non glycosylated proteins of about 30kDa.	tmpzr1t_l9r_go_relaxed.owl	expansin					This term was made obsolete because it represents a gene product.	GO:0009505|GO:0016049				True			molecular_function											owl:Class	
GO:0000299	biolink:NamedThing	obsolete integral to membrane of membrane fraction	OBSOLETE. Integral to that fraction of cells, prepared by disruptive biochemical methods, that includes the plasma and other membranes; require detergents, such as Triton X-100, to be released from membranes.	tmpzr1t_l9r_go_relaxed.owl	integral to membrane of membrane fraction					This term was made obsolete because it refers to a cell fractionation experimental result and not a bona fide cellular component.	GO:0016021				True			cellular_component											owl:Class	
GO:1904012	biolink:NamedThing	obsolete platinum binding	OBSOLETE. Binding to platinum.	tmpzr1t_l9r_go_relaxed.owl						The reason for obsoletion is that binding to platinum does not have physiological relevance.		sl	2015-03-06T19:07:37Z		True			molecular_function											owl:Class	
GO:0072366	biolink:NamedThing	obsolete regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter	OBSOLETE. Any process that modulates the frequency, rate or extent of a cellular ketone metabolic process by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter.	tmpzr1t_l9r_go_relaxed.owl	regulation of cellular ketone metabolic process by positive regulation of transcription from an RNA polymerase II promoter|regulation of cellular ketone metabolism by positive regulation of transcription from an RNA polymerase II promoter					This term was obsoleted because it represents a GO-CAM model.		mah	2010-11-16T03:12:47Z		True			biological_process											owl:Class	
GO:0052346	biolink:NamedThing	obsolete positive regulation by organism of defense-related symbiont nitric oxide production	OBSOLETE. Any process in which an organism activates, maintains or increases the frequency, rate or extent of the production of nitric oxide as part of the defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	positive regulation by organism of defense-related symbiont NO production|positive regulation by organism of defense-related symbiont nitric oxide production					This term was made obsolete because it does not represent a real biological process.					True			biological_process											owl:Class	
GO:0031602	biolink:NamedThing	obsolete ER proteasome core complex	OBSOLETE. The core complex of a proteasome located in the endoplasmic reticulum of a cell.	tmpzr1t_l9r_go_relaxed.owl						This term was made obsolete because there is no evidence in the literature of its existence.					True			cellular_component											owl:Class	
GO:0075076	biolink:NamedThing	obsolete positive regulation by host of symbiont adenylate cyclase activity	OBSOLETE. Any process in which the host organism activates, maintains or increases the frequency, rate or extent of the symbiont adenylate cyclase activity, which catalyze the reaction: ATP = 3',5'-cyclic AMP + diphosphate. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl		This term was obsoleted because it represents a molecular function.				This term was obsoleted because it represents a molecular function.					True			biological_process											owl:Class	
GO:1904166	biolink:NamedThing	obsolete negative regulation of cholesterol homeostasis	OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of cholesterol homeostasis.	tmpzr1t_l9r_go_relaxed.owl	downregulation of cholesterol homeostasis|inhibition of cholesterol homeostasis|down-regulation of cholesterol homeostasis|down regulation of cholesterol homeostasis					This term was obsoleted at the TermGenie Gatekeeper stage.		rph	2015-04-22T11:11:12Z		True			biological_process											owl:Class	
GO:0006129	biolink:NamedThing	obsolete protein-disulfide reduction	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	protein-disulfide reduction|protein-disulphide reduction					This term was made obsolete because it represents a molecular function rather than a biological process.	GO:0022900|GO:0019153				True			biological_process											owl:Class	
GO:0000005	biolink:NamedThing	obsolete ribosomal chaperone activity	OBSOLETE. Assists in the correct assembly of ribosomes or ribosomal subunits in vivo, but is not a component of the assembled ribosome when performing its normal biological function.	tmpzr1t_l9r_go_relaxed.owl	ribosomal chaperone activity					This term was made obsolete because it refers to a class of gene products and a biological process rather than a molecular function.	GO:0042254|GO:0051082|GO:0044183				True			molecular_function											owl:Class	
RO:0002230	biolink:NamedThing	ends with		tmpzr1t_l9r_go_relaxed.owl					RO:0002230									external									ends_with			
GO:0100014	biolink:NamedThing	obsolete positive regulation of mating type switching by transcription from RNA polymerase II promoter	OBSOLETE. Any transcription from RNA polymerase II promoter process that positively regulates mating type switching.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it represents a GO-CAM model.		cjm	2015-04-02T04:13:19Z		True			biological_process											owl:Class	
RO:0002592	biolink:NamedThing	results in organization of		tmpzr1t_l9r_go_relaxed.owl					RO:0002592									external									results_in_organization_of			
GO:0060477	biolink:NamedThing	obsolete peptidyl-serine phosphorylation involved in acrosome reaction	OBSOLETE. The phosphorylation of peptidyl-serine to form peptidyl-O-phospho-L-serine that is part of the acrosome reaction.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/14281				The reason for obsoletion is that this term does not represent a specific process.					True			biological_process											owl:Class	
GO:0052328	biolink:NamedThing	obsolete interaction with symbiont via protein secreted by type III secretion system	OBSOLETE. An interaction with the symbiont organism mediated by a substance secreted by the other organism by a type III secretion system. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	interaction with symbiont via protein secreted by type III secretion system					This term was made obsolete because it does not represent a real biological process.					True			biological_process											owl:Class	
GO:0009491	biolink:NamedThing	obsolete redox-active disulfide bond electron carrier	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	redox-active disulfide bond electron carrier|redox-active disulphide bond electron carrier			GO:0009055		This term was made obsolete because it refers to a class of gene products.					True			molecular_function											owl:Class	
GO:0052418	biolink:NamedThing	obsolete metabolism by organism of protein in other organism involved in symbiotic interaction	OBSOLETE. The chemical reactions and pathways performed by an organism involving protein macromolecules within a second organism, where the two organisms are in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	metabolism by organism of protein in other organism during symbiotic interaction					This term was obsoleted because it represents an unnecessary grouping class.					True			biological_process											owl:Class	
GO:0052569	biolink:NamedThing	obsolete response to defense-related symbiont nitric oxide production	OBSOLETE. A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of nitric oxide produced as part of the defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	response to defense-related symbiont nitric oxide production					This term was made obsolete because it does not represent a real biological process.					True			biological_process											owl:Class	
GO:0000187	biolink:NamedThing	obsolete activation of MAPK activity	OBSOLETE. The initiation of the activity of the inactive enzyme MAP kinase (MAPK).	tmpzr1t_l9r_go_relaxed.owl	activation of MAPK activity during sporulation|MAPK activation|activation of MAP kinase	https://github.com/geneontology/go-ontology/issues/21307				This term was obsoleted because it represents a molecular function.	GO:0000165|GO:0043539				True			biological_process											owl:Class	
GO:0001724	biolink:NamedThing	obsolete type III intermediate filament associated protein	OBSOLETE. Proteins that associate with the ends of intermediate filaments and couple the intermediate filaments to the plasma membrane.	tmpzr1t_l9r_go_relaxed.owl	type III intermediate filament associated protein			GO:0045098		This term was made obsolete because it represents a single gene product and not a complex.					True			cellular_component											owl:Class	
GO:0003709	biolink:NamedThing	obsolete RNA polymerase III transcription factor activity	OBSOLETE. Functions to initiate or regulate RNA polymerase III transcription.	tmpzr1t_l9r_go_relaxed.owl	RNA polymerase III transcription factor activity					This term was obsoleted because it is essentially identical to a Process term (specifically the Biological Process term which has been selected as a term to consider for reannotation), i.e. it is defined only in terms of the process it acts in and it does NOT convey any information about the molecular nature of the function or whether the function is based on binding DNA, on interacting with other proteins, or some other mechanism. To transfer all annotations without review, the BP term indicated is considered to be equivalent and thus the only appropriate destination for all annotations. To reannotate to a MF term, you will probably need to revisit the original literature or other primary data because this "MF" term was not defined in terms of mechanism of action and there are multiple possibilities in the revised MF structure. In reannotation, please also consider descendent terms of the suggested MF terms as a more specific term may be more appropriate than the MF terms indicated. Please be aware that you may wish to request a new term if the mechanism of action of this gene product is not yet represented or if you are annotating for an RNAP different than one for which there is a specific suggested term. Also note that if there is no information about how the gene product acts, it may be appropriate to annotate to the root term for molecular_function.	GO:0000995|GO:0006383				True			molecular_function											owl:Class	
GO:0050424	biolink:NamedThing	obsolete alanine carboxypeptidase activity	OBSOLETE. Catalysis of the reaction: H2O + peptidyl-L-alanine = L-alanine + peptide. The release of a C-terminal alanine from a peptide or a variety of pteroyl or acyl groups.	tmpzr1t_l9r_go_relaxed.owl	N-benzoyl-L-alanine-amidohydrolase activity|alanine carboxypeptidase activity			GO:0004181		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0003820	biolink:NamedThing	obsolete class I major histocompatibility complex antigen	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	class I major histocompatibility complex antigen					This term was made obsolete because it represents a gene product, and because describing something as an 'antigen' means that an organism can produce antibodies to it, which says nothing about the gene product activity.	GO:0042612				True			molecular_function											owl:Class	
GO:0052451	biolink:NamedThing	obsolete modulation by organism of symbiont inflammatory response	OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of the inflammatory response of a symbiont organism; the inflammatory response is the immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	modulation by organism of symbiont inflammatory response					This term was made obsolete because it does not represent a real biological process.					True			biological_process											owl:Class	
GO:0006762	biolink:NamedThing	obsolete dihydrofolate reduction	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	dihydrofolate reduction					This term was made obsolete because it represents a molecular function rather than a biological process.	GO:0004146|GO:0046452				True			biological_process											owl:Class	
GO:0030147	biolink:NamedThing	obsolete natriuresis	OBSOLETE. The process of renal sodium excretion.	tmpzr1t_l9r_go_relaxed.owl	natriuresis				Wikipedia:Natriuresis	This term was made obsolete because its definition was inaccurate.	GO:0035815				True			biological_process											owl:Class	
GO:0039544	biolink:NamedThing	obsolete suppression by virus of host RIG-I activity by RIG-I proteolysis	OBSOLETE. The chemical reactions and pathways performed by a virus resulting in the hydrolysis of the host RIG-I protein (also known as DDX58) by cleavage of peptide bonds, thereby inhibiting RIG-I signal transduction.	tmpzr1t_l9r_go_relaxed.owl	inhibition by virus of host RIG-I activity by RIG-I proteolysis|cleavage of RIG-I by viral proteinase					The reason for obsoleting this term is that it is too specific. The exact molecular roles of the individual proteins should be captured separately.		bf	2012-01-18T02:30:29Z		True			biological_process											owl:Class	
GO:0052133	biolink:NamedThing	obsolete positive aerotaxis in host	OBSOLETE. The directed movement of a motile cell or organism towards a higher concentration of environmental oxygen within its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	positive aerotaxis within host	https://github.com/geneontology/go-ontology/issues/18819				This term was obsoleted because it represents both a process and a location.					True			biological_process											owl:Class	
GO:0052171	biolink:NamedThing	obsolete growth or development during symbiotic interaction	OBSOLETE. The increase in size or mass of an organism, or the progression of an organism from an initial condition to a later condition, occurring when the organism is in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	growth or development during symbiotic interaction					This term was made obsolete because it contained a conjunction (or).	GO:0044111				True			biological_process											owl:Class	
GO:2000602	biolink:NamedThing	obsolete regulation of interphase of mitotic cell cycle	OBSOLETE. Any process that modulates the frequency, rate or extent of interphase of mitotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl	regulation of interphase of mitotic cell cycle					This term was made obsolete as part of the cell cycle overhaul. This is because it was decided that cell cycle phases are intervals and so cannot be regulated, rather it is the transitions between the phases that are regulated.		pr	2011-04-15T03:52:25Z		True			biological_process											owl:Class	
GO:0005066	biolink:NamedThing	obsolete transmembrane receptor protein tyrosine kinase signaling protein activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	transmembrane receptor protein tyrosine kinase signalling protein activity|transmembrane receptor protein tyrosine kinase signaling protein activity					This term was made obsolete because the meaning of the term is ambiguous and it incorporates process information.	GO:0007169|GO:0035556				True			molecular_function											owl:Class	
GO:0006495	biolink:NamedThing	obsolete terminal O-glycosylation	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	terminal O-glycosylation					This term was made obsolete because there is no evidence for the existence of this process.					True			biological_process											owl:Class	
GO:0004786	biolink:NamedThing	obsolete Mn, Fe superoxide dismutase	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	Mn, Fe superoxide dismutase					This term was made obsolete because the function is covered by an existing term.	GO:0004784				True			molecular_function											owl:Class	
GO:0072469	biolink:NamedThing	obsolete detection of stimulus involved in cell size control checkpoint	OBSOLETE. The series of events in which information about cell size is received and converted into a molecular signal, contributing to a cell size control checkpoint.	tmpzr1t_l9r_go_relaxed.owl	cell size control checkpoint sensor process|sensing involved in cell size control checkpoint|cell size control checkpoint sensor mechanism|detection of stimulus involved in mitotic cell cycle cell size control checkpoint	https://github.com/geneontology/go-ontology/issues/20976				This term was obsoleted because it corresponds to a molecular function.		mah	2010-12-09T11:46:08Z		True			biological_process											owl:Class	
GO:0075335	biolink:NamedThing	obsolete positive regulation of symbiont adenylate cyclase-mediated signal transduction in response to host	OBSOLETE. Any process in which the symbiont organism activates, maintains or increases the frequency, rate or extent of its adenylate cyclase-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because there is no evidence that this process exists.					True			biological_process											owl:Class	
GO:0008189	biolink:NamedThing	obsolete apoptosis inhibitor activity	OBSOLETE. The function held by products which directly block any step in the process of apoptosis.	tmpzr1t_l9r_go_relaxed.owl	apoptosis inhibitor activity			GO:0043066		This term was made obsolete because it represents involvement in a biological process.					True			molecular_function											owl:Class	
GO:0071509	biolink:NamedThing	obsolete activation of MAPKK activity involved in conjugation with cellular fusion	OBSOLETE. Any process that initiates the activity of the inactive enzyme MAP kinase kinase in the context of conjugation with cellular fusion.	tmpzr1t_l9r_go_relaxed.owl	activation of MAPKK activity involved in mating response|activation of MAP kinase kinase activity during conjugation with cellular fusion|conjugation with cellular fusion, activation of MAPKK activity|conjugation with cellular fusion, activation of MAP kinase kinase activity	https://github.com/geneontology/go-ontology/issues/20242				This term was obsoleted because it represents a GO-CAM model.		mah	2010-01-05T02:09:58Z		True			biological_process											owl:Class	
GO:0019027	biolink:NamedThing	obsolete ambisense viral genome	OBSOLETE. A RNA genome that contains coding regions that are either positive sense or negative sense on the same RNA molecule.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it does not represent a GO cellular component.					True			cellular_component											owl:Class	
GO:0052234	biolink:NamedThing	obsolete negative aerotaxis on or near other organism involved in symbiotic interaction	OBSOLETE. The directed movement of a motile cell or organism towards a lower concentration of environmental oxygen on or near a second organism, where the two organisms are in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	negative aerotaxis on or near other organism during symbiotic interaction	https://github.com/geneontology/go-ontology/issues/18819				This term was obsoleted because it represents both a process and a location.					True			biological_process											owl:Class	
GO:0075023	biolink:NamedThing	obsolete MAPK-mediated regulation of appressorium formation	OBSOLETE. Any process that modulates the frequency, rate or extent of symbiont MAP kinase-mediated signal transduction during appressorium formation on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	mitogen-activated protein kinase-mediated activation of appressorium formation					This term was obsoleted because it represents a GO-CAM model.					True			biological_process											owl:Class	
GO:0075022	biolink:NamedThing	obsolete ethylene-mediated activation of appressorium formation	OBSOLETE. Any process that modulates the frequency, rate or extent of symbiont ethylene-mediated signal transduction during appressorium formation on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it represents a GO-CAM model.					True			biological_process											owl:Class	
GO:0003687	biolink:NamedThing	obsolete DNA replication factor	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	DNA replication factor					This term was made obsolete because it does not represent a true molecular function.	GO:0006260				True			molecular_function											owl:Class	
GO:0015479	biolink:NamedThing	obsolete outer membrane exporter porin	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	outer membrane exporter porin					This term was made obsolete because it contains both component and function information.	GO:0009279|GO:0015288				True			molecular_function											owl:Class	
GO:0106182	biolink:NamedThing	obsolete translocase activity acting on amino acids and peptides.	OBSOLETE. Catalysis of the translocation of amino acids and peptides.	tmpzr1t_l9r_go_relaxed.owl					EC:7.4.-.-	This term was made obsolete because the concept of using the non-4 digit EC classes as parent terms for the transporter banch of the onotolgy was consided confusing.		hjd	2019-04-05T15:52:34Z		True			molecular_function											owl:Class	
GO:0044051	biolink:NamedThing	obsolete interaction with host via substance released by symbiont cytolysis	OBSOLETE. An interaction with the host organism mediated by a substance released via cytolysis of symbiont cells. Cytolysis is the rupture of cell membranes and the loss of cytoplasm. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	interaction with host via substance released by cytolysis of symbiont					This term was obsoleted because it conflates a process and the mechanism of secretion of the gene product mediating the process.					True			biological_process											owl:Class	
GO:0004250	biolink:NamedThing	obsolete aminopeptidase I activity	OBSOLETE. Catalysis of the release of an N-terminal amino acid, preferably a neutral or hydrophobic one, from a polypeptide. Aminoacyl-arylamides are poor substrates.	tmpzr1t_l9r_go_relaxed.owl	vacuolar aminopeptidase I activity|aminopeptidase III activity|yeast aminopeptidase I|aminopeptidase yscI activity|aminopeptidase I activity|leucine aminopeptidase IV activity				EC:3.4.11.22|MetaCyc:3.4.11.22-RXN	This term was made obsolete because it represents a gene product.	GO:0004177|GO:0008235				True			molecular_function											owl:Class	
GO:0052146	biolink:NamedThing	obsolete positive energy taxis on or near host	OBSOLETE. The directed movement of a motile cell or organism on or near its host organism towards a higher level of a physical stimulus involved in energy generation, such as light, oxygen, and oxidizable substrates. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/18819				This term was obsoleted because it represents both a process and a location.					True			biological_process											owl:Class	
GO:0006462	biolink:NamedThing	obsolete protein complex assembly, multichaperone pathway	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	protein complex assembly, multichaperone pathway					This term was made obsolete because the string was ambiguous and the original meaning of the term was hence unknown.	GO:0051131|GO:0006457				True			biological_process											owl:Class	
GO:1990855	biolink:NamedThing	obsolete myo-inositol import across plasma membrane	OBSOLETE. The directed movement of myo-inositol from outside of a cell into the intracellular region of a cell across the plasma membrane.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted at the TermGenie Gatekeeper stage.		al	2015-09-17T16:52:32Z		True			biological_process											owl:Class	
GO:0030827	biolink:NamedThing	obsolete negative regulation of cGMP biosynthetic process	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cGMP.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of cGMP biosynthesis|downregulation of cGMP biosynthetic process|down-regulation of cGMP biosynthetic process|inhibition of cGMP biosynthetic process|negative regulation of cGMP synthesis|negative regulation of cGMP anabolism|negative regulation of cGMP formation|down regulation of cGMP biosynthetic process					The reason for obsoletion is that the term represents the regulation of a signaling pathway, and not regulation of metabolism.	GO:0030251				True			biological_process											owl:Class	
GO:0060597	biolink:NamedThing	obsolete regulation of transcription from RNA polymerase II promoter involved in mammary gland formation	OBSOLETE. Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the formation of the mammary line, placode or bud.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it represents a GO-CAM model.	GO:0030879|GO:0060592|GO:0006357	dph	2009-05-13T12:04:53Z		True			biological_process											owl:Class	
GO:0102131	biolink:NamedThing	obsolete 3-oxo-glutaryl-[acp] methyl ester reductase activity	OBSOLETE. Catalysis of the reaction: NADP + a 3R-hydroxyglutaryl-[acp] methyl ester <=> NADPH + H+ + a 3-oxo-glutaryl-[acp] methyl ester.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/21876				This term was obsoleted because it represents a specific substrate, and is beyond the specificity of GO.	GO:0004316				True			molecular_function											owl:Class	
GO:0005564	biolink:NamedThing	obsolete cytosolic tRNA	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	cytosolic tRNA					Note that this term was deleted from GO and was restored to the ontology in Feb 2003 to ensure that the ID is not reused.					True			cellular_component											owl:Class	
GO:0003815	biolink:NamedThing	obsolete complement component C1r activity	OBSOLETE. Catalysis of the selective cleavage of Lys(or Arg)-Ile bond in complement subcomponent C1s to form the active form of C1s (EC:3.4.21.42).	tmpzr1t_l9r_go_relaxed.owl	activated complement C1r|C1r esterase activity|complement component C1r activity|complement subcomponent C1r			GO:0004252		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0001300	biolink:NamedThing	obsolete chronological cell aging	OBSOLETE. The process associated with progression of the cell from its inception to the end of its lifespan that occurs when the cell is in a non-dividing, or quiescent, state.	tmpzr1t_l9r_go_relaxed.owl	chronological cell ageing	https://github.com/geneontology/go-ontology/issues/18632				This term was obsoleted because it represent an assay - how long the cell lives -, not a true biological process.	GO:0044838|GO:0090398				True			biological_process											owl:Class	
GO:0030939	biolink:NamedThing	obsolete response to long-day photoperiod	OBSOLETE. A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a photoperiod, an intermittent cycle of light (day) and dark (night) photoperiod regimes, with the light phase being longer than the dark.	tmpzr1t_l9r_go_relaxed.owl	response to long-day photoperiod					This term was made obsolete because it was wrongly defined.	GO:0048571				True			biological_process											owl:Class	
GOREL:0002003	biolink:NamedThing	results_in_distribution_of		tmpzr1t_l9r_go_relaxed.owl					GOREL:0002003									external									results_in_distribution_of			
GO:0006380	biolink:NamedThing	obsolete poly-A binding	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	poly-A binding					This term was made obsolete because it represents a molecular function and not a biological process.	GO:0008143				True			biological_process											owl:Class	
GO:0015340	biolink:NamedThing	obsolete zinc, cadmium uptake permease activity	OBSOLETE. Catalysis of the reaction: (Zn2+ or Cd2+)(out) = (Zn2+ or Cd2+)(in). The activity is driven by proton motive force, possibly by proton symport.	tmpzr1t_l9r_go_relaxed.owl	zinc, cadmium uptake permease activity					This term was made obsolete because it represents more than one molecular function.	GO:0015086|GO:0005385				True			molecular_function											owl:Class	
GO:0052406	biolink:NamedThing	obsolete metabolism by host of symbiont carbohydrate	OBSOLETE. The chemical reactions and pathways performed by an organism involving carbohydrates within the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/21469				This term was obsoleted because it represents a molecular function.					True			biological_process											owl:Class	
GO:0033220	biolink:NamedThing	obsolete ATPase-coupled amide-transporter activity	OBSOLETE. Catalysis of the reaction: ATP + H2O + amide(out) = ADP + phosphate + amide(in).	tmpzr1t_l9r_go_relaxed.owl	ATP-dependent amide-transporter activity|amide-transporting ATPase activity					This term was obsoleted because it is an unnecessary grouping class.					True			molecular_function											owl:Class	
GO:0008438	biolink:NamedThing	obsolete 1-phosphatidylinositol-5-phosphate kinase	OBSOLETE. Catalysis of the reaction: diphosphate + a purine nucleoside = phosphate + a purine mononucleotide.	tmpzr1t_l9r_go_relaxed.owl	1-phosphatidylinositol-5-phosphate kinase					This term was made obsolete because it is a redundant grouping term with only one child. It is also incorrectly defined and had an incorrect EC dbxref.	GO:0016309				True			molecular_function											owl:Class	
GO:0052048	biolink:NamedThing	obsolete interaction with host via secreted substance	OBSOLETE. An interaction with the host organism mediated by a substance secreted by the other (symbiont) organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	interaction with host via secreted substance involved in symbiotic interaction|interaction with host via secreted substance during symbiotic interaction					This term was obsoleted because it conflates a process and the mechanism of secretion of the gene product mediating the process.					True			biological_process											owl:Class	
GO:0004243	biolink:NamedThing	obsolete mitochondrial intermediate peptidase activity	OBSOLETE. Catalysis of the release of an N-terminal octapeptide as second stage of processing of some proteins imported in the mitochondrion.	tmpzr1t_l9r_go_relaxed.owl	mitochondrial intermediate precursor-processing proteinase activity|mitochondrial intermediate peptidase activity|MIP			GO:0004222		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:1990581	biolink:NamedThing	obsolete lysosome lysis	OBSOLETE. The rupture of the lysosomal membrane and loss of contents as a result of osmotic change, G-protein-driven disintegration, or unspecified cause.	tmpzr1t_l9r_go_relaxed.owl	lysosomal lysis|lysosome lysis					This term was obsoleted at the TermGenie Gatekeeper stage.		sl	2014-12-10T18:54:00Z		True			biological_process											owl:Class	
GO:0031658	biolink:NamedThing	obsolete negative regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of cyclin-dependent protein serine/threonine kinase activity contributing to the G1/S transition of the cell cycle.	tmpzr1t_l9r_go_relaxed.owl	G1/S-specific inhibition of cyclin-dependent protein kinase activity|G1/S-specific negative regulation of cyclin-dependent protein kinase activity|G1/S-specific downregulation of cyclin-dependent protein kinase activity|negative regulation of cyclin-dependent protein kinase activity during G1/S|negative regulation of cyclin-dependent protein kinase activity involved in G1/S|G1/S-specific down regulation of cyclin-dependent protein kinase activity|G1/S-specific down-regulation of cyclin-dependent protein kinase activity					The term has been obsoleted because it represents a GO-CAM model.					True			biological_process											owl:Class	
GO:0051404	biolink:NamedThing	obsolete clostripain activity	OBSOLETE. Catalysis of the cleavage of Arg-Xaa bonds.	tmpzr1t_l9r_go_relaxed.owl	alpha-clostridipain|clostripain activity|clostridiopeptidase B activity|Clostridium histolyticum proteinase B			GO:0004197		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0140603	biolink:NamedThing	obsolete ATP hydrolysis activity	OBSOLETE. Catalysis of the reaction: ATP + H2O = ADP + H+ Pi. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/20876		GO:0016887		This term was deprecated because it was created in the wrong branch on the ontology.		pg	2021-02-12T18:57:14Z		True			molecular_function											owl:Class	
GO:0106199	biolink:NamedThing	obsolete translocase activity acting on amino acids and peptides linked to oxidoreductase reactions	OBSOLETE. Catalysis of the translocation of amino acids and peptides linked to oxidoreductase reactions.	tmpzr1t_l9r_go_relaxed.owl					EC:7.4.1.-	This term was made obsolete because the concept of using the non-4 digit EC classes as parent terms for the transporter banch of the onotolgy was consided confusing.		hjd	2019-05-08T18:23:04Z		True			molecular_function											owl:Class	
GO:0046542	biolink:NamedThing	obsolete alpha-factor export	OBSOLETE. The directed movement of alpha-factor, one of the two yeast mating factors, out of a cell.	tmpzr1t_l9r_go_relaxed.owl	alpha-factor export					This term was made obsolete because it is a gene product based term and it does not involve a unique process.	GO:0015833				True			biological_process											owl:Class	
GO:0000205	biolink:NamedThing	obsolete activation of MAPK during sporulation (sensu Saccharomyces)	OBSOLETE. Upregulation of MAP kinase activity in the context of sporulation. As in, but not restricted to, the taxon Saccharomyces (Saccharomyces, ncbi_taxonomy_id:4930).	tmpzr1t_l9r_go_relaxed.owl	activation of MAPK during sporulation (sensu Saccharomyces)					This term was made obsolete because it is a gene product specific term.					True			biological_process											owl:Class	
GO:0043329	biolink:NamedThing	obsolete protein targeting to membrane involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway	OBSOLETE. The process of directing proteins towards a membrane using signals contained within the protein, occurring that contributes to ubiquitin-dependent protein catabolism via the MVB pathway; the destruction of a protein or peptide covalently tagged with a ubiquitin, via the multivesicular body (MVB) sorting pathway.	tmpzr1t_l9r_go_relaxed.owl	protein targeting to membrane during ubiquitin-dependent protein catabolic process via the MVB pathway|protein-membrane targeting during ubiquitin-dependent protein breakdown via the MVB pathway|protein targeting to membrane during ubiquitin-dependent protein degradation via the MVB pathway|protein-membrane targeting during ubiquitin-dependent protein degradation via the MVB pathway|protein-membrane targeting during ubiquitin-dependent protein catabolism via the MVB pathway|protein targeting to membrane during ubiquitin-dependent protein breakdown via the MVB pathway|protein membrane targeting during ubiquitin-dependent protein catabolic process via the MVB pathway|protein-membrane targeting during ubiquitin-dependent protein catabolic process via the MVB pathway|protein membrane targeting during ubiquitin-dependent protein catabolism via the MVB pathway					The reason for obsoleting is that the term is not cleary defined, ie the membrane to which proteins are being targeted is not specified.					True			biological_process											owl:Class	
GO:0080010	biolink:NamedThing	obsolete regulation of oxygen and reactive oxygen species metabolic process	OBSOLETE. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving dioxygen (O2), or any of the reactive oxygen species, e.g. superoxide anions (O2-), hydrogen peroxide (H2O2), and hydroxyl radicals (-OH).	tmpzr1t_l9r_go_relaxed.owl	regulation of oxygen and reactive oxygen species metabolic process					This term was made obsolete because, as part of the GO/ChEBI alignment effort, curators determined that oxygen and reactive oxygen species should not be grouped together.	GO:2000374|GO:2000377				True			biological_process											owl:Class	
GO:0007257	biolink:NamedThing	obsolete activation of JUN kinase activity	OBSOLETE. The initiation of the activity of the inactive enzyme JUN kinase (JNK).	tmpzr1t_l9r_go_relaxed.owl	activation of SAPK activity	https://github.com/geneontology/go-ontology/issues/21307					GO:0007254|GO:0043539				True			biological_process											owl:Class	
GO:0030569	biolink:NamedThing	obsolete chymotrypsin inhibitor activity	OBSOLETE. Stops, prevents or reduces the activity of the serine endopeptidase chymotrypsin.	tmpzr1t_l9r_go_relaxed.owl	chymotrypsin inhibitor activity			GO:0004867		This term was made obsolete because it represents a regulator of an obsolete molecular function term.					True			molecular_function											owl:Class	
GO:0016911	biolink:NamedThing	obsolete SAP kinase 4 activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	SAPK4|SAP kinase 4 activity					This term was made obsolete because it describes a gene product.	GO:0004674|GO:0007254				True			molecular_function											owl:Class	
GO:0075170	biolink:NamedThing	obsolete negative regulation of protein kinase-mediated signal transduction in response to host	OBSOLETE. Any process in which the symbiont organism stops, prevents, or reduces the frequency, rate or extent of its symbiont protein kinase-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of symbiont protein kinase-mediated signal transduction in response to host					This term was obsoleted because there is no evidence that this process exists.					True			biological_process											owl:Class	
GO:0017030	biolink:NamedThing	obsolete beta-galactosidase stabilization activity	OBSOLETE. Stabilization of the structure of beta-galactosidase.	tmpzr1t_l9r_go_relaxed.owl	beta-galactosidase stabilization activity			GO:0050821		This term was made obsolete because it represents a biological process.					True			molecular_function											owl:Class	
GO:0005907	biolink:NamedThing	obsolete HA1 clathrin adaptor	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	HA1 clathrin adaptor|AP1					This term was made obsolete as part of a general reorganization of vesicle and vesicle coat terms; its position in the ontology was erroneous.	GO:0030121				True			cellular_component											owl:Class	
GO:0007170	biolink:NamedThing	obsolete transmembrane receptor protein tyrosine kinase ligand binding	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	transmembrane receptor protein tyrosine kinase ligand binding					This term was made obsolete because it represents a function rather than a process.	GO:0030971				True			biological_process											owl:Class	
GO:0007115	biolink:NamedThing	obsolete bud site selection/establishment of cell polarity (sensu Saccharomyces)	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	bud site selection/establishment of cell polarity (sensu Saccharomyces)					This term was made obsolete because it represents two processes.	GO:0000282|GO:0030010				True			biological_process											owl:Class	
GO:1905252	biolink:NamedThing	obsolete regulation of epidermal growth factor receptor signaling pathway involved in heart process	OBSOLETE. Any regulation of epidermal growth factor receptor signaling pathway that is involved in heart process.	tmpzr1t_l9r_go_relaxed.owl	regulation of EGF receptor signaling pathway involved in cardiac process|regulation of EGFR signaling pathway involved in cardiac process|regulation of EGF receptor signalling pathway involved in heart process|regulation of EGF receptor signaling pathway involved in heart process|regulation of EGF receptor signalling pathway involved in cardiac process|regulation of epidermal growth factor receptor signaling pathway involved in cardiac process|regulation of EGFR signaling pathway involved in heart process					This term was obsoleted at the TermGenie Gatekeeper stage.		bc	2016-06-10T09:21:02Z		True			biological_process											owl:Class	
GO:1905548	biolink:NamedThing	obsolete negative regulation of subtelomeric heterochromatin assembly	OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of subtelomeric heterochromatin assembly.	tmpzr1t_l9r_go_relaxed.owl	downregulation of telomeric heterochromatin assembly|downregulation of telomeric heterochromatin formation|down-regulation of telomeric heterochromatin formation|negative regulation of telomeric heterochromatin assembly|negative regulation of telomeric heterochromatin formation|inhibition of telomeric heterochromatin formation|inhibition of telomeric heterochromatin assembly|down-regulation of telomeric heterochromatin assembly|down regulation of telomeric heterochromatin assembly|down regulation of telomeric heterochromatin formation	https://github.com/geneontology/go-ontology/issues/22027|https://github.com/geneontology/go-ontology/issues/19188				This term was obsoleted because there is no evidence that chromatin silencing /heterochromatin assembly are directly regulated.		nc	2016-10-12T11:18:23Z		True			biological_process											owl:Class	
GO:0019738	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052147	biolink:NamedThing	obsolete positive energy taxis in host	OBSOLETE. The directed movement of a motile cell or organism within its host organism towards a higher level of a physical stimulus involved in energy generation, such as light, oxygen, and oxidizable substrates. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	positive energy taxis within host	https://github.com/geneontology/go-ontology/issues/18819				This term was obsoleted because it represents both a process and a location.					True			biological_process											owl:Class	
GO:0006927	biolink:NamedThing	obsolete transformed cell apoptotic process	OBSOLETE. Any apoptotic process in a transformed cell, a cell that has undergone changes manifested by escape from control mechanisms, increased growth potential, alterations in the cell surface, karyotypic abnormalities, morphological and biochemical deviations from the norm.	tmpzr1t_l9r_go_relaxed.owl	transformed cell programmed cell death by apoptosis|programmed cell death, transformed cells|programmed cell death of transformed cells by apoptosis|transformed cell apoptosis|killing transformed cells|apoptosis of transformed cells					This term was made obsolete because it does not refer to a normal process.					True			biological_process											owl:Class	
GO:0018997	biolink:NamedThing	obsolete electron transfer carrier	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	electron transfer carrier					This term was made obsolete because the parent terms cover its function.	GO:0009055				True			molecular_function											owl:Class	
GO:0015613	biolink:NamedThing	obsolete galactose/glucose (methylgalactoside) porter activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	galactose/glucose (methylgalactoside) porter activity					This term was made obsolete because it represents a multifunctional gene product.	GO:0015592|GO:0005355|GO:0005354|GO:0015291				True			molecular_function											owl:Class	
GO:0015072	biolink:NamedThing	obsolete phosphatidylinositol 3-kinase, class I, catalyst activity	OBSOLETE. Catalysis of the reaction: ATP + 1-phosphatidyl-1D-myo-inositol = ADP + 1-phosphatidyl-1D-myo-inositol 3-phosphate.	tmpzr1t_l9r_go_relaxed.owl	phosphatidylinositol 3-kinase, class I, catalyst activity					This term was made obsolete because it represents a class of gene products.	GO:0046934|GO:0016303|GO:0035005				True			molecular_function											owl:Class	
GO:0016694	biolink:NamedThing	obsolete bacterial catalase-peroxidase activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	bacterial catalase-peroxidase activity					This term was made obsolete because it represents a bifunctional gene product.	GO:0004601|GO:0004096				True			molecular_function											owl:Class	
GO:0000051	biolink:NamedThing	obsolete urea cycle intermediate metabolic process	OBSOLETE. The chemical reactions and pathways involving any of the intermediate compounds involved in the urea cycle, a cyclic metabolic pathway that converts waste nitrogen in the form of ammonium to urea.	tmpzr1t_l9r_go_relaxed.owl	urea cycle intermediate metabolic process|urea cycle intermediate metabolism					This term was made obsolete because it is a grouping term that is not useful, but has caused true path violations.					True			biological_process											owl:Class	
RO:0012003	biolink:NamedThing	acts on population of		tmpzr1t_l9r_go_relaxed.owl					RO:0012003									external									acts_on_population_of			
GO:0005396	biolink:NamedThing	obsolete transmembrane conductance regulator activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	transmembrane conductance regulator activity					This term was made obsolete because its meaning was ambiguous, it was undefined and its position in the tree wrong.	GO:0043267				True			molecular_function											owl:Class	
GO:0052013	biolink:NamedThing	obsolete catabolism by symbiont of host macromolecule	OBSOLETE. The chemical reactions and pathways performed by an organism resulting in the breakdown of macromolecules within the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	catabolism by organism of host macromolecule	https://github.com/geneontology/go-ontology/issues/21469				This term was obsoleted because it represents a molecular function.					True			biological_process											owl:Class	
GO:0008144	biolink:NamedThing	obsolete drug binding	OBSOLETE. Binding to a drug, a naturally occurring or synthetic substance, other than a nutrient, that, when administered or applied to an organism, affects the structure or functioning of the organism;typically used in the diagnosis, prevention, or treatment of disease.	tmpzr1t_l9r_go_relaxed.owl						It is not meaningful to describe a molecular function by what role a compound may be used for at some times.					True			molecular_function											owl:Class	
GO:1990364	biolink:NamedThing	obsolete response to aldehyde	OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an aldehyde.	tmpzr1t_l9r_go_relaxed.owl	response to aldehyde					This term was obsoleted at the TermGenie Gatekeeper stage.		tt	2014-04-23T22:18:04Z		True			biological_process											owl:Class	
GO:1902376	biolink:NamedThing	obsolete protein denaturation involved in proteasomal ubiquitin-dependent protein catabolic process	OBSOLETE. Any protein denaturation that is involved in proteasomal ubiquitin-dependent protein catabolic process.	tmpzr1t_l9r_go_relaxed.owl	protein denaturation involved in proteasomal processing|protein denaturation involved in proteasomal ubiquitin-dependent protein catabolism|protein denaturation involved in proteasome pathway|protein denaturation involved in proteasomal pathway|protein denaturation involved in proteasomal ubiquitin-dependent protein breakdown|protein denaturation involved in proteasomal ubiquitin-dependent protein degradation					This term was made obsolete because it was poorly defined and the intended usage was unclear.		al	2013-08-30T09:29:14Z		True			biological_process											owl:Class	
GO:0052066	biolink:NamedThing	obsolete entry of symbiont into host cell by promotion of host phagocytosis	OBSOLETE. The invasion by a symbiont of a host organism cell by utilizing the host phagocytosis mechanism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	penetration of organism into host cell by promotion of host phagocytosis|entry of organism into cell of other organism by promotion of phagocytosis in other organism involved in symbiotic interaction|entry of organism into host cell by promotion of host phagocytosis|entry of organism into cell of other organism by promotion of phagocytosis in other organism during symbiotic interaction|penetration of symbiont into host cell by promotion of host phagocytosis	https://github.com/geneontology/go-ontology/issues/18562				This term was obsoleted because it was misused.					True			biological_process											owl:Class	
GO:0023050	biolink:NamedThing	obsolete consequence of signal transmission	OBSOLETE. The steps whereby the downstream processes started by a signal are brought to a conclusion. Examples include destruction of cAMP by PDE, or endocytosis resulting from receptor phosphorylation. The termination process ends when the receptor has returned to its inactive state.	tmpzr1t_l9r_go_relaxed.owl	consequence of signal transmission|signal termination					This term was made obsolete because the term is no longer needed.			2010-02-16T09:30:50Z		True			biological_process											owl:Class	
GO:0051883	biolink:NamedThing	obsolete killing of cells in other organism involved in symbiotic interaction	OBSOLETE. Any process mediated by an organism that results in the death of cells in a second organism, where the two organisms are in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	killing of cells in other organism during symbiotic interaction					This term was obsoleted because it represents an unnecessary grouping class.					True			biological_process											owl:Class	
GO:0019017	biolink:NamedThing	obsolete segmented viral genome	OBSOLETE. A viral genome that is divided into two or more physically separate molecules of nucleic acid and packaged into a single virion.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it does not represent a GO cellular component.					True			cellular_component											owl:Class	
GO:0008246	biolink:NamedThing	obsolete electron transfer flavoprotein	OBSOLETE. Works in conjunction with acyl-CoA dehydrogenase to catalyze the oxidation of CoA and reduce ubiquinone. Part of the mitochondrial electron transport system.	tmpzr1t_l9r_go_relaxed.owl	ETF|electron transfer flavoprotein			GO:0009055		This term was made obsolete because it refers to a class of gene products.					True			molecular_function											owl:Class	
GO:0048622	biolink:NamedThing	obsolete reproductive sporulation	OBSOLETE. The formation of reproductive spores.	tmpzr1t_l9r_go_relaxed.owl	reproductive sporulation					This term was made obsolete because it was ambiguously defined and incorrectly placed in the ontology.					True			biological_process											owl:Class	
GO:0006377	biolink:NamedThing	obsolete MATa1 (A1) pre-mRNA splicing	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	MATa1 (A1) pre-mRNA splicing					This term was made obsolete because it does not represent a process unique to splicing of the MATa1 (A1) pre-mRNA, but a recycling defect exacerbated by the presence of two introns within the same gene.	GO:0000244				True			biological_process											owl:Class	
GO:0100017	biolink:NamedThing	obsolete negative regulation of cell-cell adhesion by transcription from RNA polymerase II promoter	OBSOLETE. Any transcription from RNA polymerase II promoter process that negatively regulates single organismal cell-cell adhesion.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it represents a GO-CAM model.		cjm	2015-04-02T04:13:19Z		True			biological_process											owl:Class	
GO:0075149	biolink:NamedThing	obsolete negative regulation of signal transduction in response to host	OBSOLETE. Any process in which the symbiont organism stops, prevents, or reduces the frequency, rate or extent of its signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of symbiont signal transduction in response to host					This term was obsoleted because there is no evidence that this process exists.					True			biological_process											owl:Class	
GO:0075083	biolink:NamedThing	obsolete negative regulation by host of symbiont transmembrane receptor-mediated signal transduction	OBSOLETE. Any process in which the host organism stops, prevents, or reduces the frequency, rate or extent of transmembrane receptor-mediated signal transduction in the symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl						The reason for obsoletion is that there is no evidence that the host can modulate or regulate a symbiont's signal transduction pathway.					True			biological_process											owl:Class	
GO:0006199	biolink:NamedThing	obsolete ADP reduction	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	ADP reduction					This term was made obsolete because it represents a molecular function rather than a biological process.	GO:0051061				True			biological_process											owl:Class	
GO:0100054	biolink:NamedThing	obsolete positive regulation of flocculation via cell wall protein-carbohydrate interaction by transcription from RNA polymerase II promoter	OBSOLETE. Any transcription from RNA polymerase II promoter process that positively regulates flocculation via cell wall protein-carbohydrate interaction.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it represents a GO-CAM model.		cjm	2015-04-02T04:13:19Z		True			biological_process											owl:Class	
GO:0004229	biolink:NamedThing	obsolete gelatinase B activity	OBSOLETE. Catalysis of the cleavage of gelatin types I and V and collagen types IV and V.	tmpzr1t_l9r_go_relaxed.owl	matrix metalloproteinase 9 activity|macrophage gelatinase activity|collagenase IV|collagenase type IV|gelatinase B activity|gelatinase MMP 9|92-kDa type IV collagenase activity|95 kDa type IV collagenase/gelatinase activity|MMP 9|type IV collagen metalloproteinase|MMP-9|92-kDa gelatinase activity|type V collagenase activity			GO:0004222		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0005065	biolink:NamedThing	obsolete heterotrimeric G-protein	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	heterotrimeric G-protein			GO:0005834		This term was made obsolete because it represents a cellular component and not a molecular function.					True			molecular_function											owl:Class	
GO:0103053	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0018248	biolink:NamedThing	obsolete enzyme active site formation via peptidyl cysteine sulfation	OBSOLETE. The formation of an enzyme active site via transient sulfation of peptidyl-cysteine to form S-sulfo-L-cysteine.	tmpzr1t_l9r_go_relaxed.owl	enzyme active site formation via S-sulpho-L-cysteine	https://github.com/geneontology/go-ontology/issues/15594				This term was obsoleted because it was created by error: cysteine sulfation is a post-translational modification, see PMID:12876326.					True			biological_process											owl:Class	
GO:0045567	biolink:NamedThing	obsolete negative regulation of TRAIL receptor 2 biosynthetic process	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of TRAIL (TNF-related apoptosis inducing ligand) receptor 2.	tmpzr1t_l9r_go_relaxed.owl	downregulation of TRAIL receptor 2 biosynthetic process|negative regulation of TRAIL receptor 2 biosynthesis|inhibition of TRAIL receptor 2 biosynthetic process|negative regulation of TRAIL receptor 2 anabolism|negative regulation of TRAIL receptor 2 formation|down regulation of TRAIL receptor 2 biosynthetic process|negative regulation of TRAIL receptor 2 synthesis|down-regulation of TRAIL receptor 2 biosynthetic process	https://github.com/geneontology/go-ontology/issues/19900				The reason for obsoletion is that those represent specific gene products, and genes annotated to those terms should be annotated to 'regulation of gene expression' or 'regulation of transcription' or some signaling term.					True			biological_process											owl:Class	
GO:0019268	biolink:NamedThing	obsolete glutamate biosynthetic process, using glutamate dehydrogenase (NAD(P)+)	OBSOLETE. The chemical reactions and pathways resulting in the formation of glutamate, catalyzed by the enzyme glutamate dehydrogenase (NADP+).	tmpzr1t_l9r_go_relaxed.owl	glutamate anabolism, using glutamate dehydrogenase (NAD(P)+)|glutamate synthesis, using glutamate dehydrogenase (NAD(P)+)|glutamate formation, using glutamate dehydrogenase (NAD(P)+)|glutamate biosynthetic process, using glutamate dehydrogenase (NAD(P)+)					This term was made obsolete because it represents a molecular function.	GO:0006537|GO:0004353				True			biological_process											owl:Class	
GO:0007236	biolink:NamedThing	obsolete activation of Ssk1 protein	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	activation of Ssk1 protein					This term was made obsolete because it contains gene product and species specific information.					True			biological_process											owl:Class	
GO:0051925	biolink:NamedThing	obsolete regulation of calcium ion transport via voltage-gated calcium channel activity	OBSOLETE. Any process that modulates the frequency, rate or extent of the directed movement of calcium ions via a voltage-gated calcium channel.	tmpzr1t_l9r_go_relaxed.owl	regulation of calcium ion transport via voltage-gated calcium channel activity|regulation of calcium transport via voltage-gated calcium channel					This term was made obsolete because it is ill-defined: channel activities are part of ion transport processes, and not the other way round.	GO:0005245				True			biological_process											owl:Class	
GO:0015017	biolink:NamedThing	obsolete glypican	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	glypican					This term was made obsolete because it represents a gene product (was misspelled 'glycipan').					True			molecular_function											owl:Class	
GO:0005429	biolink:NamedThing	obsolete chromaffin granule amine transmembrane transporter activity	OBSOLETE. Enables the transfer of amines across chromaffin granule membranes.	tmpzr1t_l9r_go_relaxed.owl						The term was obsoleted because its intended usage was unclear: chromaffin granules are dense core secretory vesicles (PMID:20853344) so whatever they transport must be by secretion.					True			molecular_function											owl:Class	
GO:0100038	biolink:NamedThing	obsolete regulation of cellular response to oxidative stress by transcription from RNA polymerase II promoter	OBSOLETE. Any transcription from RNA polymerase II promoter process that regulates cellular response to oxidative stress.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it represents a GO-CAM model.		cjm	2015-04-02T04:13:19Z		True			biological_process											owl:Class	
GO:0052438	biolink:NamedThing	obsolete modulation by organism of defense-related symbiont callose deposition	OBSOLETE. Any process by which an organism modulates the frequency, rate or extent of callose deposition by the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	modulation by organism of defense-related symbiont callose deposition					This term was made obsolete because it does not represent a real biological process.					True			biological_process											owl:Class	
GO:0019764	biolink:NamedThing	obsolete high affinity Fc receptor activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	high affinity Fc receptor activity					This term was made obsolete because it is an unnecessary grouping term.	GO:0019771|GO:0019768				True			molecular_function											owl:Class	
GO:0052417	biolink:NamedThing	obsolete metabolism by host of symbiont protein	OBSOLETE. The chemical reactions and pathways performed by an organism involving protein macromolecules within the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/21469				This term was obsoleted because it represents a molecular function.					True			biological_process											owl:Class	
GO:0100013	biolink:NamedThing	obsolete positive regulation of fatty acid beta-oxidation by transcription from RNA polymerase II promoter	OBSOLETE. Any transcription from RNA polymerase II promoter process that positively regulates fatty acid beta-oxidation.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it represents a GO-CAM model.		cjm	2015-04-02T04:13:19Z		True			biological_process											owl:Class	
GO:0042808	biolink:NamedThing	obsolete neuronal Cdc2-like kinase binding	OBSOLETE. Binding to neuronal Cdc2-like kinase, an enzyme involved in the regulation of neuronal differentiation and neuro-cytoskeleton dynamics.	tmpzr1t_l9r_go_relaxed.owl	neuronal Cdc2-like kinase binding			GO:0019901		This term was made obsolete because it represents binding to an individual protein.					True			molecular_function											owl:Class	
GO:0001319	biolink:NamedThing	obsolete inheritance of oxidatively modified proteins involved in replicative cell aging	OBSOLETE. A protein localization process in which progeny cells acquire, or are barred from acquiring, proteins that have been altered by reaction with reactive oxygen species in dividing aging cells.	tmpzr1t_l9r_go_relaxed.owl	inheritance of oxidatively modified proteins during replicative cell ageing|inheritance of oxidatively modified proteins during replicative cell aging	https://github.com/geneontology/go-ontology/issues/20007				This term was obsoleted because it represents an assay, not a true biological process.					True			biological_process											owl:Class	
GO:2000154	biolink:NamedThing	obsolete negative regulation of flagellar cell motility	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of flagellar cell motility.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of flagellar cell motility					This term was made obsolete because microtubule-based flagellum (GO:0009434) and motile cilium (GO:0031514), as referenced by this term, were determined to be equivalent and merged. When a merge for this term was considered, it was noticed that both eukaryotic and prokaryotic proteins are annotated to it because its meaning had been ambiguous so obsoletion was considered safest.	GO:1902020|GO:1902201	mah	2010-10-04T12:41:04Z		True			biological_process											owl:Class	
GO:0019038	biolink:NamedThing	obsolete provirus	OBSOLETE. The name given to a viral genome after it has been integrated into the host genome; particularly applies to retroviruses and is a required part of the retroviral replication cycle.	tmpzr1t_l9r_go_relaxed.owl					Wikipedia:Provirus	This term was obsoleted because it does not represent a GO cellular component.					True			cellular_component											owl:Class	
GO:0006731	biolink:NamedThing	obsolete coenzyme and prosthetic group metabolic process	OBSOLETE. The chemical reactions and pathways involving coenzymes and prosthetic groups.	tmpzr1t_l9r_go_relaxed.owl	coenzyme and prosthetic group metabolic process					This term was made obsolete because it was replaced by more specific terms.	GO:0051189				True			biological_process											owl:Class	
GO:0030801	biolink:NamedThing	obsolete positive regulation of cyclic nucleotide metabolic process	OBSOLETE. Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving cyclic nucleotides.	tmpzr1t_l9r_go_relaxed.owl	up regulation of cyclic nucleotide metabolic process|stimulation of cyclic nucleotide metabolic process|up-regulation of cyclic nucleotide metabolic process|upregulation of cyclic nucleotide metabolic process|positive regulation of cyclic nucleotide metabolism|activation of cyclic nucleotide metabolic process					The reason for obsoletion is that this term represents the regulation of a signaling pathway, not regulation of metabolism.					True			biological_process											owl:Class	
GO:0075153	biolink:NamedThing	obsolete regulation of transmembrane receptor-mediated signal transduction in response to host	OBSOLETE. Any process in which the symbiont organism modulates the frequency, rate or extent of its transmembrane receptor-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	regulation of symbiont transmembrane receptor-mediated signal transduction in response to host					This term was obsoleted because there is no evidence that this process exists.					True			biological_process											owl:Class	
GO:0006732	biolink:NamedThing	obsolete coenzyme metabolic process	OBSOLETE. The chemical reactions and pathways involving coenzymes, any of various nonprotein organic cofactors that are required, in addition to an enzyme and a substrate, for an enzymatic reaction to proceed.	tmpzr1t_l9r_go_relaxed.owl	group transfer coenzyme metabolic process|coenzyme metabolism|coenzyme and prosthetic group metabolism|coenzyme and prosthetic group metabolic process|group transfer coenzyme metabolism					1. Making inferences in GO about compounds based on the coenzyme role curated by ChEBI creates relationships that are not always true which violates ontological principles for GO; therefore we will cease making these inferences. 2. It is not meaningful to group metabolic processes that are not all metabolically related by the fact that they may be used as a coenzyme.					True	GO:0006752		biological_process											owl:Class	
GO:1990897	biolink:NamedThing	obsolete CTDK-1 complex	OBSOLETE. A protein complex that phosphorylates serine 2 residues in the CTD domain of productively elongating large subunits of DNA-directed RNA polymerase II, holoenzyme. In S. cerevisiae this complex consists of CTK1/CTK2/CTK3, in S. pombe Lsk1/Lsc1/Lsg1. Human CTK1 homologs include CDK12/13.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted at the TermGenie Gatekeeper stage.		al	2015-11-06T01:57:32Z		True			cellular_component											owl:Class	
GO:1905886	biolink:NamedThing	obsolete chromatin remodeling involved in meiosis I	OBSOLETE. Any chromatin remodeling that is involved in meiosis I.	tmpzr1t_l9r_go_relaxed.owl	meiosis-specific chromatin remodeling|chromatin remodelling involved in meiosis I|chromatin modelling involved in meiosis I|chromatin modeling involved in meiosis I	https://github.com/geneontology/go-ontology/issues/22036				This term was obsoleted because it represents a GO-CAM model.		mah	2017-01-31T14:29:00Z		True			biological_process											owl:Class	
GO:0033158	biolink:NamedThing	obsolete regulation of protein import into nucleus, translocation	OBSOLETE. Any process that modulates the vectorial transfer of a protein from the cytoplasm into the nucleus, across the nuclear membrane.	tmpzr1t_l9r_go_relaxed.owl	regulation of protein import into cell nucleus, translocation					This term has been obsoleted because it represents a substep of the parent (GO:0006606 protein import into nucleus), has been incorrectly used.					True			biological_process											owl:Class	
GO:0071851	biolink:NamedThing	obsolete mitotic G1 cell cycle arrest in response to nitrogen starvation	OBSOLETE. The process in which the mitotic cell cycle is halted during G1 phase, as a result of deprivation of nitrogen.	tmpzr1t_l9r_go_relaxed.owl	G1 mitotic cell cycle arrest in response to nitrogen starvation	https://github.com/geneontology/go-ontology/issues/20989				This term was obsoleted because it does not represent a specific process.		mah	2010-09-10T02:58:09Z		True			biological_process											owl:Class	
GO:0035012	biolink:NamedThing	obsolete polytene chromosome, telomeric region	OBSOLETE. The terminal region of a polytene chromosome.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/19177				This term was obsoleted because it likely represents an assay for GO:0099115 chromosome, subtelomeric region.					True			cellular_component											owl:Class	
GO:0001314	biolink:NamedThing	obsolete replication of extrachromosomal circular DNA involved in replicative cell aging	OBSOLETE. Replication of circular DNA following excision from the chromosome of dividing cells as they age; replication of extrachromosomal circular DNA generally occurs independently of chromosomal replication.	tmpzr1t_l9r_go_relaxed.owl	replication of extrachromosomal circular DNA during replicative cell aging|replication of extrachromosomal circular DNA during replicative cell ageing	https://github.com/geneontology/go-ontology/issues/20007				This term was obsoleted because it represents an assay, not a true biological process.					True			biological_process											owl:Class	
GO:0008648	biolink:NamedThing	obsolete tachykinin	OBSOLETE. A family of hormones that stimulate secretion of saliva and cause smooth muscle contraction and vasodilation.	tmpzr1t_l9r_go_relaxed.owl	tachykinin					This term was made obsolete because it represents a gene product.	GO:0046878|GO:0042311|GO:0045987|GO:0005102				True			molecular_function											owl:Class	
dct:license	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl																									owl:AnnotationProperty	
GO:0015991	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0075034	biolink:NamedThing	obsolete nuclear division involved in appressorium formation	OBSOLETE. The process in which nuclear division occurs within a symbiont spore that contributes to appressorium formation. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	nuclear division during appressorium formation on or near host|nuclear division involved in appressorium formation on or near host	https://github.com/geneontology/go-ontology/issues/21923				The reason for obsoletion is that there is no evidence that this process exists.					True			biological_process											owl:Class	
GO:0007090	biolink:NamedThing	obsolete regulation of S phase of mitotic cell cycle	OBSOLETE. A cell cycle process that modulates the frequency, rate or extent of the progression through the S phase of the mitotic cell cycle.	tmpzr1t_l9r_go_relaxed.owl	regulation of S phase of mitotic cell cycle|regulation of S-phase of mitotic cell cycle					This term was made obsolete as part of the cell cycle overhaul. This is because it was decided that cell cycle phases are intervals and so cannot be regulated, rather it is the transitions between the phases that are regulated.	GO:0044772				True			biological_process											owl:Class	
GO:0008992	biolink:NamedThing	obsolete repressor LexA activity	OBSOLETE. Catalysis of the hydrolysis of Ala-Gly bond in repressor lexA.	tmpzr1t_l9r_go_relaxed.owl	repressor LexA activity|LexA repressor|repressor lexA			GO:0004252		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:1990797	biolink:NamedThing	obsolete cholecystokinin secretion	OBSOLETE. The controlled release of cholecystokinin from a cell. Cholecystokinin is a peptide hormone that participates in pancreatic enzyme release in the gut and is also found in the brain.	tmpzr1t_l9r_go_relaxed.owl	CCK secretion					This term was obsoleted at the TermGenie Gatekeeper stage.		sl	2015-07-09T23:14:23Z		True			biological_process											owl:Class	
GO:0003794	biolink:NamedThing	obsolete acute-phase response protein activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	acute-phase response protein activity					This term was made obsolete because it refers to involvement in a biological process.	GO:0006953				True			molecular_function											owl:Class	
GO:0006441	biolink:NamedThing	obsolete binding to mRNA cap	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	binding to mRNA cap					This term was made obsolete because it represents a function rather than a process.	GO:0000339				True			biological_process											owl:Class	
GO:0033805	biolink:NamedThing	obsolete sarcosine/dimethylglycine N-methyltransferase activity	OBSOLETE. Catalysis of the reactions: S-adenosyl-L-methionine + sarcosine = S-adenosyl-L-homocysteine + N,N-dimethylglycine, and S-adenosyl-L-methionine + N,N-dimethylglycine = S-adenosyl-L-homocysteine + betaine.	tmpzr1t_l9r_go_relaxed.owl	sarcosine/dimethylglycine N-methyltransferase activity|S-adenosyl-L-methionine:N,N-dimethylglycine N-methyltransferase activity|SDMT|sarcosine dimethylglycine N-methyltransferase activity|sarcosine dimethylglycine methyltransferase activity|ApDMT					This term was made obsolete because it represents two reactions, and should be two separate terms.	GO:0052729|GO:0052730				True			molecular_function											owl:Class	
GO:0052369	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0075305	biolink:NamedThing	obsolete modulation of growth or development of symbiont on or near host	OBSOLETE. Any process by which the symbiont regulates the increase in its size or mass, or its progression from an initial condition to a later condition, on or near the cells or tissues of the host organism.	tmpzr1t_l9r_go_relaxed.owl	modulation of growth or development of symbiont on or near host surface|modulation of growth or development of symbiont on or near host					This term was made obsolete because it contained a conjunction (or).					True			biological_process											owl:Class	
GO:0052486	biolink:NamedThing	obsolete negative regulation by organism of symbiont innate immunity	OBSOLETE. Any process by which an organism stops, prevents, or reduces the frequency, rate or extent of the innate immune response of the symbiont organism, the symbiont's first line of defense against infection. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of symbiont innate immune response|negative regulation by organism of symbiont innate immunity					This term was made obsolete because it does not represent a real biological process.					True			biological_process											owl:Class	
GO:0075096	biolink:NamedThing	obsolete modulation by host of symbiont signal transduction mediated by G-protein gamma subunit	OBSOLETE. Any process in which the host organism modulates the frequency, rate or extent of the symbiont signal transduction mediated by G-protein gamma subunit. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl						The reason for obsoletion is that there is no evidence that the host can modulate or regulate a symbiont's signal transduction pathway.					True			biological_process											owl:Class	
GO:0052466	biolink:NamedThing	obsolete modulation by organism of symbiont resistance gene-dependent defense response	OBSOLETE. Any process by which an organism activates, maintains or increases the frequency, rate or extent of the resistance gene-dependent defense response of the symbiont. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	modulation by organism of pathogen-race/symbiont plant cultivar-specific resistance in symbiont|modulation by organism of symbiont gene-for-gene resistance|modulation by organism of symbiont resistance gene-dependent defense response|modulation by organism of defense response in symbiont by specific elicitors					This term was made obsolete because it does not represent a real biological process.					True			biological_process											owl:Class	
GO:0004187	biolink:NamedThing	obsolete carboxypeptidase D activity	OBSOLETE. Catalysis of the preferential release of a C-terminal arginine or lysine residue. Function is inhibited by diisopropyl fluorophosphate and sensitive to thiol-blocking reagents.	tmpzr1t_l9r_go_relaxed.owl	cereal serine carboxypeptidase II|saccharomyces cerevisiae KEX1 gene product|carboxypeptidase S1 activity|CPDW-II|KEX1DELTAp|KEX1 carboxypeptidase activity|carboxypeptidase KEX1 activity|carboxypeptidase D activity|KEX1 proteinase activity|carboxypeptidase Kex1|gene KEX1 serine carboxypeptidase			GO:0004185		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0005318	biolink:NamedThing	obsolete phosphate:hydrogen symporter	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	phosphate:hydrogen symporter|phosphate:proton symporter activity						GO:0015317				True			molecular_function											owl:Class	
GO:0044397	biolink:NamedThing	obsolete actin cortical patch internalization	OBSOLETE. A process of actin cortical patch localization in which the patch moves from the cell surface to the inside of the cell.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/20490		GO:0006897		The reason for obsoletion is that it represents a phenotype.		jl	2011-12-21T03:37:11Z		True			biological_process											owl:Class	
GO:0016354	biolink:NamedThing	obsolete cyclodiene susceptibility/resistance	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	cyclodiene susceptibility/resistance			GO:0046682		This term was made obsolete because 'susceptibility/resistance' implies a phenotype rather than a biological process.					True			biological_process											owl:Class	
GO:0003685	biolink:NamedThing	obsolete DNA repair protein	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	DNA repair protein					This term was made obsolete because it includes a process term.	GO:0003684				True			molecular_function											owl:Class	
RO:0002427	biolink:NamedThing	causally downstream of or within		tmpzr1t_l9r_go_relaxed.owl					RO:0002427									external									causally_downstream_of_or_within			
GO:0052425	biolink:NamedThing	obsolete modification by organism of symbiont morphology or physiology via protein secreted by type II secretion system	OBSOLETE. The process by which an organism effects a change in the structure or function of its symbiont organism, mediated by a substance secreted by a type II secretion system in the organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	modification by organism of symbiont morphology or physiology via protein secreted by type II secretion system					This term was made obsolete because it does not represent a real biological process.					True			biological_process											owl:Class	
GO:0031935	biolink:NamedThing	obsolete regulation of chromatin silencing	OBSOLETE. Any process that affects the rate, extent or location of chromatin silencing.	tmpzr1t_l9r_go_relaxed.owl	regulation of heterochromatic silencing	https://github.com/geneontology/go-ontology/issues/22060				This term was obsoleted because it was too vague: regulation of chromatin (gene) silencing takes place via upstream signaling pathways.					True			biological_process											owl:Class	
GO:0030455	biolink:NamedThing	obsolete MAPKKK cascade (mating sensu Fungi)	OBSOLETE. MAPKKK cascade involved in transducing mating pheromone signal in a fungus.	tmpzr1t_l9r_go_relaxed.owl	MAPKKK cascade (mating sensu Fungi)			GO:0000750		This term was made obsolete because it is a gene product specific term.					True			biological_process											owl:Class	
GO:0008034	biolink:NamedThing	obsolete lipoprotein binding	OBSOLETE. Binding to a conjugated, water-soluble protein in which the nonprotein group consists of a lipid or lipids.	tmpzr1t_l9r_go_relaxed.owl	lipoprotein binding					This term was made obsolete because its text definition and implicit ontology-structure definition disagreed, and as a result the term had been used in annotations with more than one meaning.	GO:0071723|GO:0071813				True			molecular_function											owl:Class	
GO:0008220	biolink:NamedThing	obsolete necrosis	OBSOLETE. The processes that cause necrosis, the death of tissues, in another organism.	tmpzr1t_l9r_go_relaxed.owl	necrosis					This term was made obsolete because the term has been used in the literature by groups in different areas of biology with a number of varying explicit and implicit definitions, and more appropriate terms were created.	GO:0001906|GO:0008219|GO:0012501|GO:0070265|GO:0019835				True			biological_process											owl:Class	
GO:0003792	biolink:NamedThing	obsolete regulation of actin thin filament length activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	regulation of actin thin filament length activity			GO:0030832		This term was made obsolete because the term belongs in the process ontology.					True			molecular_function											owl:Class	
GO:0070272	biolink:NamedThing	obsolete proton-transporting ATP synthase complex biogenesis	OBSOLETE. The biogenesis of a proton-transporting ATP synthase (also known as F-type ATPase), a two-sector ATPase found in the inner membrane of mitochondria and chloroplasts, and in bacterial plasma membranes. Includes the synthesis of constituent proteins and their aggregation, arrangement and bonding together.	tmpzr1t_l9r_go_relaxed.owl	F-type ATPase complex biogenesis	https://github.com/geneontology/go-ontology/issues/15173				The reason for obsoletion is that 'biogenesis' as related to a protein is translation, and there is no indication that the members of these complexes are synthesized in a particular way. Historically biogenesis terms were created for some processes when the level of a molecule was changed by an unknown mechanism, for instance transcription, translation, assembly etc. This is now considered too indirect for annotation.					True			biological_process											owl:Class	
GO:0042378	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0075175	biolink:NamedThing	obsolete positive regulation of cAMP-mediated signaling in response to host	OBSOLETE. Any process in which the symbiont organism activates, maintains or increases the frequency, rate or extent of its cAMP-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of symbiont cAMP-mediated signal transduction in response to host|positive regulation of cAMP-mediated signalling in response to host|positive regulation of cAMP-mediated signal transduction in response to host					This term was obsoleted because there is no evidence that this process exists.					True			biological_process											owl:Class	
GO:0019022	biolink:NamedThing	obsolete RNA viral genome	OBSOLETE. A viral genome composed of ribonucleic acid. This results in genome replication and expression of genetic information being inextricably linked.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it does not represent a GO cellular component.					True			cellular_component											owl:Class	
GO:0052492	biolink:NamedThing	obsolete negative regulation by host of symbiont signal transduction pathway	OBSOLETE. Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of the symbiont signal transduction pathways, the cascade of processes by which a signal interacts with a receptor. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	inhibition by host of symbiont signal transduction pathway|down-regulation by host of symbiont signal transduction pathway|down regulation by host of symbiont signal transduction pathway|downregulation by host of symbiont signal transduction pathway|negative modulation by organism of symbiont signal transduction pathway					The reason for obsoletion is that there is no evidence that the host can modulate or regulate a symbiont's signal transduction pathway.					True			biological_process											owl:Class	
RO:0002339	biolink:NamedThing	has target end location		tmpzr1t_l9r_go_relaxed.owl					RO:0002339									external									has_target_end_location			
GO:1990056	biolink:NamedThing	obsolete protein kinase activity required for targeting substrate to proteasomal ubiquitin-dependent protein catabolic process	OBSOLETE. Catalysis of the phosphorylation of an amino acid residue in a substrate protein, usually according to the reaction: a protein + ATP = a phosphoprotein + ADP, thereby targeting the substrate to the proteasomal ubiquitin mediated protein catabolic process.	tmpzr1t_l9r_go_relaxed.owl	protein kinase activity required for targeting substrate to proteasomal ubiquitin-dependent protein catabolic process					This term was obsoleted at the TermGenie Gatekeeper stage.		rb	2013-02-26T21:28:08Z		True			molecular_function											owl:Class	
GO:0009280	biolink:NamedThing	obsolete cell wall inner membrane	OBSOLETE. In Gram-negative bacteria the membrane that separates the cytoplasm from the murein sacculus.	tmpzr1t_l9r_go_relaxed.owl	cytoplasmic membrane|cell wall inner membrane					This term was made obsolete because it was defined inaccurately.	GO:0009276				True			cellular_component											owl:Class	
GO:0004627	biolink:NamedThing	obsolete calcium-dependent cytosolic phospholipase A2 activity	OBSOLETE. Catalysis of the reaction: phosphatidylcholine + H2O = 1-acylglycerophosphocholine + a fatty acid anion.	tmpzr1t_l9r_go_relaxed.owl	calcium-dependent cytosolic phospholipase A2 activity					This term was made obsolete because it represents component and function information.	GO:0005829|GO:0047498				True			molecular_function											owl:Class	
GO:0052145	biolink:NamedThing	obsolete negative energy taxis on or near host	OBSOLETE. The directed movement of a motile cell or organism on or near its host organism towards a lower level of a physical stimulus involved in energy generation, such as light, oxygen, and oxidizable substrates. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/18819				This term was obsoleted because it represents both a process and a location.					True			biological_process											owl:Class	
GO:0075157	biolink:NamedThing	obsolete positive regulation of G protein-coupled receptor signaling pathway in response to host	OBSOLETE. Any process in which the symbiont organism activates, maintains or increases the frequency, rate or extent of its G protein-coupled receptor-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of G-protein coupled receptor protein signalling pathway in response to host|positive regulation of symbiont G-protein coupled receptor protein-mediated signal transduction in response to host|positive regulation of G-protein coupled receptor protein signaling pathway in response to host					This term was obsoleted because there is no evidence that this process exists.					True			biological_process											owl:Class	
GO:0043499	biolink:NamedThing	obsolete eukaryotic cell surface binding	OBSOLETE. Binding to a component on the surface of a eukaryotic cell.	tmpzr1t_l9r_go_relaxed.owl	eukaryotic cell surface binding					This term was made obsolete because it is ambiguous and causing confusion, and is an unnecessary grouping term.	GO:0046812|GO:0009986|GO:0005102|GO:0003823|GO:0006952				True			molecular_function											owl:Class	
GO:0052196	biolink:NamedThing	obsolete negative regulation by host of symbiont defense response	OBSOLETE. Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of the defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	downregulation by host of symbiont defense response|inhibition by host of symbiont defense response|down-regulation by host of symbiont defense response|down regulation by host of symbiont defense response	https://github.com/geneontology/go-ontology/issues/14862				This term was made obsolete because it is not relevant for the host in a host-symbiont interaction.					True			biological_process											owl:Class	
GO:0075178	biolink:NamedThing	obsolete positive regulation of calcium or calmodulin-mediated signal transduction in response to host	OBSOLETE. Any process in which the symbiont organism activates, maintains or increases the frequency, rate or extent of its calcium or calmodulin-mediated signal transduction as a result of detecting host molecules in, on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of symbiont calcium or calmodulin-mediated signal transduction in response to host|positive regulation of symbiont Ca++ or calmodulin-mediated signal transduction in response to host					This term was obsoleted because there is no evidence that this process exists.					True			biological_process											owl:Class	
GO:0008051	biolink:NamedThing	obsolete farnesyl-diphosphate farnesyl transferase complex	OBSOLETE. A complex that possesses farnesyl-diphosphate farnesyl transferase activity.	tmpzr1t_l9r_go_relaxed.owl	farnesyl-diphosphate farnesyl transferase complex					This term was made obsolete because there is no evidence that this enzyme ever exists as anything other than a monomer.	GO:0004310				True			cellular_component											owl:Class	
GO:0019024	biolink:NamedThing	obsolete ssRNA viral genome	OBSOLETE. A viral genome composed of single stranded RNA of either positive or negative sense.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it does not represent a GO cellular component.					True			cellular_component											owl:Class	
GO:0061392	biolink:NamedThing	obsolete regulation of transcription from RNA polymerase II promoter in response to osmotic stress	OBSOLETE. Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/12739				This term was obsoleted because it represents a GO-CAM model.	GO:0006357|GO:0071470	dph	2011-12-13T08:52:04Z		True			biological_process											owl:Class	
GO:0019019	biolink:NamedThing	obsolete tripartite viral genome	OBSOLETE. A segmented viral genome consisting of three sub-genomic nucleic acids but each nucleic acid is packaged into a different virion.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it does not represent a GO cellular component.					True			cellular_component											owl:Class	
GO:0072477	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0080158	biolink:NamedThing	obsolete chloroplast ribulose bisphosphate carboxylase complex biogenesis	OBSOLETE. A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a chloroplast ribulose bisphosphate carboxylase (RubisCO) complex. Includes the synthesis of the constituent protein molecules, and those protein modifications that are involved in synthesis or assembly of the complex.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/15173				The reason for obsoletion is that 'biogenesis' as related to a protein is translation, and there is no indication that the members of these complexes are synthesized in a particular way. Historically biogenesis terms were created for some processes when the level of a molecule was changed by an unknown mechanism, for instance transcription, translation, assembly etc. This is now considered too indirect for annotation.		dhl	2010-09-01T04:05:55Z		True			biological_process											owl:Class	
GO:0043411	biolink:NamedThing	obsolete myopalladin binding	OBSOLETE. Binding to myopalladin, a myofibrillar protein with titin-like Ig domains.	tmpzr1t_l9r_go_relaxed.owl	myopalladin binding			GO:0008092		This term was made obsolete because it represents binding to an individual protein.					True			molecular_function											owl:Class	
GO:0003926	biolink:NamedThing	obsolete ARF small monomeric GTPase activity	OBSOLETE. Catalysis of the reaction: GTP + H2O = GDP + phosphate.	tmpzr1t_l9r_go_relaxed.owl	ARF small monomeric GTPase activity			GO:0003924		This term was made obsolete because it represents a gene product.	GO:0016192|GO:0016191				True			molecular_function											owl:Class	
GO:0106192	biolink:NamedThing	obsolete translocase activity acting on inorganic cations and their chelates linked to the hydrolysis of a nucleoside triphosphate	OBSOLETE. Catalysis of the translocation of inorganic cations and their chelates linked to the hydrolysis of a nucleoside triphosphate.	tmpzr1t_l9r_go_relaxed.owl						This term was made obsolete because the concept of using the non-4 digit EC classes as parent terms for the transporter banch of the onotolgy was consided confusing.		hjd	2019-05-08T16:52:54Z		True			molecular_function											owl:Class	
RO:0002008	biolink:NamedThing	coincident with		tmpzr1t_l9r_go_relaxed.owl					RO:0002008									external									coincident_with			
GO:0061618	biolink:NamedThing	obsolete sublamina densa	OBSOLETE. The part of the basement membrane that lies beneath the lamina densa, containing anchoring fibrils, anchoring plaques, collagen fibers, and elastic fibers.	tmpzr1t_l9r_go_relaxed.owl						This term was made obsolete because it is thought to be an experimental artefact.		dph	2014-04-14T08:43:13Z		True			cellular_component											owl:Class	
GO:0019849	biolink:NamedThing	obsolete cytotoxin activity	OBSOLETE. Acts as to cause injury to other living cells.	tmpzr1t_l9r_go_relaxed.owl	cytotoxin activity					This term was made obsolete because it represents a class of gene products.	GO:0090729				True			molecular_function											owl:Class	
GO:0008547	biolink:NamedThing	obsolete protein-synthesizing GTPase activity	OBSOLETE. Catalysis of the reaction: GTP + H2O = GDP + phosphate. A GTPase involved in protein synthesis. In the initiation factor complex, it is IF-2b (98 kDa) that binds GTP and subsequently hydrolyzes it in prokaryotes. In eukaryotes, it is eIF-2 (150 kDa) that binds GTP. In the elongation phase, the GTP-hydrolyzing proteins are the EF-Tu polypeptide of the prokaryotic transfer factor (43 kDa), the eukaryotic elongation factor EF-1a (53 kDa), the prokaryotic EF-G (77 kDa), the eukaryotic EF-2 (70-110 kDa) and the signal recognition particle that play a role in endoplasmic reticulum protein synthesis (325 kDa). EF-Tu and EF1a catalyze binding of aminoacyl-tRNA to the ribosomal A-site, while EF-G and EF-2 catalyze the translocation of peptidyl-tRNA from the A-site to the P-site. GTPase activity is also involved in polypeptide release from the ribosome with the aid of the pRFs and eRFs.	tmpzr1t_l9r_go_relaxed.owl	protein-synthesizing GTPase activity					This term was made obsolete because it represents a gene product.	GO:0006412|GO:0008135|GO:0003924				True			molecular_function											owl:Class	
GO:0052047	biolink:NamedThing	obsolete symbiotic process mediated by secreted substance	OBSOLETE. An interaction with a second organism mediated by a substance secreted by the first organism, where the two organisms are in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	interaction with other organism via secreted substance during symbiotic interaction|interaction with other organism via secreted substance involved in symbiotic interaction					This term was obsoleted because it has been misused to annotate host proteins.					True			biological_process											owl:Class	
GO:0052217	biolink:NamedThing	obsolete aerotaxis in environment of other organism involved in symbiotic interaction	OBSOLETE. The movement of a motile cell or organism in response to environmental oxygen on, within or near a second organism, where the two organisms are in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	aerotaxis in environment of other organism during symbiotic interaction|aerotaxis in response to environment of other organism	https://github.com/geneontology/go-ontology/issues/18819				This term was obsoleted because it represents both a process and a location.					True			biological_process											owl:Class	
GO:0030609	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0005348	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0075080	biolink:NamedThing	obsolete negative regulation by host of symbiont receptor-mediated signal transduction	OBSOLETE. Any process in which the host organism stops, prevents, or reduces the frequency, rate or extent of receptor-mediated signal transduction in the symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl						The reason for obsoletion is that there is no evidence that the host can modulate or regulate a symbiont's signal transduction pathway.					True			biological_process											owl:Class	
GO:0006326	biolink:NamedThing	obsolete bent DNA binding	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	bent DNA binding			GO:0003681		This term was made obsolete because it represents a molecular function and not a biological process.					True			biological_process											owl:Class	
GO:0048828	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0075085	biolink:NamedThing	obsolete positive regulation by host of symbiont transmembrane receptor-mediated cAMP signal transduction	OBSOLETE. Any process in which the host organism activates, maintains or increases the frequency, rate or extent of transmembrane receptor-mediated cAMP signal transduction in the symbiont organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	positive regulation by host of symbiont transmembrane receptor-mediated cAMP signaling|activation by host of symbiont transmembrane receptor-mediated cAMP signal transduction|promotion by host of symbiont transmembrane receptor protein activity involved in cAMP-mediated signal transduction|upregulation by host of symbiont transmembrane receptor-mediated cAMP signal transduction|stimulation by host of symbiont transmembrane receptor-mediated cAMP signal transduction					The reason for obsoletion is that there is no evidence that the host can modulate or regulate a symbiont's signal transduction pathway.					True			biological_process											owl:Class	
GO:0071571	biolink:NamedThing	obsolete LRR domain-mediated complex assembly	OBSOLETE. A process of protein complex assembly in which the arrangement and bonding together of the set of components that form the protein complex is mediated by an LRR (leucine-rich repeat) domain interaction.	tmpzr1t_l9r_go_relaxed.owl	leucine-rich repeat domain-mediated complex assembly					This term was obsoleted because it represented a molecular function (binding), not a biological process.  The term represented a domain involved in protein-protein interactions, but no necessarily the process of assembling a complex.		mah	2010-01-20T04:33:49Z		True			biological_process											owl:Class	
GO:0052006	biolink:NamedThing	obsolete catabolism by symbiont of substance in host	OBSOLETE. The chemical reactions and pathways performed by an organism in its host resulting in the breakdown of substances. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	catabolism by organism of substance in host	https://github.com/geneontology/go-ontology/issues/21469				This term was obsoleted because it represents a molecular function.					True			biological_process											owl:Class	
GO:0004892	biolink:NamedThing	obsolete B cell receptor activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	B cell receptor activity					This term was made obsolete because it describes the receptor type, and not an activity.	GO:0003823				True			molecular_function											owl:Class	
GO:0106038	biolink:NamedThing	obsolete vesicle assembly	OBSOLETE. A process carried out at the cellular level, which results in the arrangement of constituent parts of a vesicle. Vesicle assembly begins with membrane bending (GO:0097753) and ends with fusion of the vesicle after vesicle scission (GO:0099050).	tmpzr1t_l9r_go_relaxed.owl	vesicle biosynthesis|vesicle formation					This term was made obsolete because it is an exact synonym of 'membrane budding'.		hjd	2017-07-17T13:52:28Z		True			biological_process											owl:Class	
GO:0100059	biolink:NamedThing	obsolete negative regulation of phenotypic switching by transcription from RNA polymerase II promoter	OBSOLETE. Any transcription from RNA polymerase II promoter process that negatively regulates phenotypic switching.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it represents a GO-CAM model.		cjm	2015-04-02T04:13:19Z		True			biological_process											owl:Class	
RO:0002590	biolink:NamedThing	results_in_disassembly_of		tmpzr1t_l9r_go_relaxed.owl					RO:0002590									external									results_in_disassembly_of			
owl:deprecated	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl																									owl:AnnotationProperty	
GO:0097034	biolink:NamedThing	obsolete mitochondrial respiratory chain complex IV biogenesis	OBSOLETE. The biogenesis of a mitochondrial respiratory chain complex IV (also known as cytochrome c oxidase complex), a protein complex located in the mitochondrial inner membrane that forms part of the mitochondrial respiratory chain. Includes the synthesis of constituent proteins and their aggregation, arrangement and bonding together.	tmpzr1t_l9r_go_relaxed.owl	mitochondrial cytochrome c oxidase complex biogenesis	https://github.com/geneontology/go-ontology/issues/15173				The reason for obsoletion is that 'biogenesis' as related to a protein is translation, and there is no indication that the members of these complexes are synthesized in a particular way. Historically biogenesis terms were created for some processes when the level of a molecule was changed by an unknown mechanism, for instance transcription, translation, assembly etc. This is now considered too indirect for annotation.		pr	2011-04-05T03:02:54Z		True			biological_process											owl:Class	
GO:0008329	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0000044	biolink:NamedThing	obsolete ascorbate stabilization	OBSOLETE. The reduction of the ascorbate free radical to a stable form.	tmpzr1t_l9r_go_relaxed.owl	vitamin C stabilization|ascorbate stabilization					This term was made obsolete because it is defined as a function term and is in the process ontology.					True			biological_process											owl:Class	
GO:0045713	biolink:NamedThing	obsolete low-density lipoprotein particle receptor biosynthetic process	OBSOLETE. The chemical reactions and pathways resulting in the formation of low-density lipoprotein receptors, cell surface proteins that mediate the endocytosis of low-density lipoprotein particles by cells.	tmpzr1t_l9r_go_relaxed.owl	LDLr biosynthetic process|low-density lipoprotein receptor formation|low-density lipoprotein receptor biosynthesis|LDLr biosynthesis|low-density lipoprotein receptor anabolism|low-density lipoprotein receptor biosynthetic process|low-density lipoprotein receptor synthesis	https://github.com/geneontology/go-ontology/issues/19900				The reason for obsoletion is that those represent specific gene products, and genes annotated to those terms should be annotated to 'regulation of gene expression' or 'regulation of transcription' or some signaling term.					True			biological_process											owl:Class	
GO:0075205	biolink:NamedThing	obsolete modulation by host of symbiont cAMP-mediated signal transduction	OBSOLETE. Any process in which the host organism modulates the frequency, rate or extent of cAMP-mediated signal transduction in the symbiont. The cAMP-mediated signal transduction is defined as a series of molecular signals in which a cell uses cyclic AMP to convert an extracellular signal into a response. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	modulation by host of symbiont cAMP-mediated signalling|regulation by host of symbiont cAMP-mediated signaling|modulation by host of symbiont cAMP-mediated signaling					The reason for obsoletion is that there is no evidence that the host can modulate or regulate a symbiont's signal transduction pathway.					True			biological_process											owl:Class	
GO:1903154	biolink:NamedThing	obsolete glucose transmembrane transporter activity involved in glucose import into cell	OBSOLETE. Any glucose transmembrane transporter activity that is involved in glucose import into cell.	tmpzr1t_l9r_go_relaxed.owl	glucose permease activity involved in glucose import into cell|lactose/glucose efflux transporter activity involved in glucose import into cell|glucose transmembrane transporter activity involved in glucose import into cell|galactose/glucose (methylgalactoside) porter activity involved in glucose import into cell					This term was obsoleted at the TermGenie Gatekeeper stage.		dos	2014-07-09T11:55:59Z		True			molecular_function											owl:Class	
GO:0071167	biolink:NamedThing	obsolete ribonucleoprotein complex import into nucleus	OBSOLETE. The directed movement of a ribonucleoprotein complex from the cytoplasm to the nucleus.	tmpzr1t_l9r_go_relaxed.owl	ribonucleoprotein complex targeting to nucleus|ribonucleoprotein complex nucleus import|ribonucleoprotein complex transport from cytoplasm to nucleus|RNP import into nucleus|ribonucleoprotein import into nucleus|ribonucleoprotein complex import into cell nucleus					The reason for obsoletion is that all proteins are imported into the nucleus via the same mechanism, so the import of individual proteins should be captured with extensions or by GO-CAM models.	GO:0006606	mah	2009-11-19T04:48:42Z		True			biological_process											owl:Class	
GO:0007237	biolink:NamedThing	obsolete activation of Ssk2/Ssk22 proteins	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	activation of Ssk2/Ssk22 proteins					This term was made obsolete because it contains gene product and species specific information.					True			biological_process											owl:Class	
GO:0100056	biolink:NamedThing	obsolete negative regulation of phosphatidylserine biosynthetic process by transcription from RNA polymerase II promoter	OBSOLETE. Any transcription from RNA polymerase II promoter process that negatively regulates phosphatidylserine biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it represents a GO-CAM model.		cjm	2015-04-02T04:13:19Z		True			biological_process											owl:Class	
GO:0070271	biolink:NamedThing	obsolete protein complex biogenesis	OBSOLETE. A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a protein complex. Includes the synthesis of non-protein components, and those protein modifications that are involved in synthesis or assembly of the complex.	tmpzr1t_l9r_go_relaxed.owl	protein complex biogenesis and assembly										True			biological_process											owl:Class	
GO:0038076	biolink:NamedThing	obsolete MAP kinase kinase activity involved in innate immune response	OBSOLETE. Catalysis of the concomitant phosphorylation of threonine (T) and tyrosine (Y) residues in a Thr-Glu-Tyr (TEY) thiolester sequence in a MAP kinase (MAPK) substrate, as part of a MAPK signaling cascade that contributes to an innate immune response.	tmpzr1t_l9r_go_relaxed.owl	MAP2K activity involved in innate immune response|MAPKK activity involved in innate immune response					This term has been obsoleted because it represents a GO-CAM model rather than a single GO term.		bf	2012-01-26T02:35:52Z		True			molecular_function											owl:Class	
GO:0044048	biolink:NamedThing	obsolete interaction with host via protein secreted by type V secretion system	OBSOLETE. An interaction with the host organism mediated by a substance secreted by the other (symbiont) organism via a type V secretion system. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it conflated the process in which a gene product is involved with the secretion system by which it reaches its target.					True			biological_process											owl:Class	
GO:0016352	biolink:NamedThing	obsolete insecticide susceptibility/resistance	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	insecticide susceptibility/resistance			GO:0017085		This term was made obsolete because 'susceptibility/resistance' implies a phenotype rather than a biological process.					True			biological_process											owl:Class	
GO:0052176	biolink:NamedThing	obsolete metabolism by symbiont of host glucan	OBSOLETE. The chemical reactions and pathways performed by an organism involving glucans within the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it represents a molecular function.					True			biological_process											owl:Class	
GO:0085002	biolink:NamedThing	obsolete interaction with host mediated by secreted substance released by symbiont from symbiotic structure	OBSOLETE. An interaction with the host organism mediated by a symbiont secreted substance released by specialized structures generated in either organisms as a result of the symbiotic interaction. The term host is used for the larger (macro) of the two members of a symbiosis.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it conflated the process in which a gene product is involved with the secretion system by which it reaches its target.		jl	2010-02-10T02:38:10Z		True			biological_process											owl:Class	
GO:0044144	biolink:NamedThing	obsolete modulation of growth of symbiont involved in interaction with host	OBSOLETE. Any process that modulates the frequency, rate or extent of the increase in size or mass of an organism occurring in, on or near the exterior of its host organism.	tmpzr1t_l9r_go_relaxed.owl	modulation of growth of symbiont during interaction with host					This term was obsoleted because it was partially redundant with other terms and its usage has been inconsistent.		jl	2009-08-06T01:56:48Z		True			biological_process											owl:Class	
GO:0019844	biolink:NamedThing	obsolete endotoxin activity	OBSOLETE. The function of any microbial toxin that cannot be easily separated from the structure of the cell.	tmpzr1t_l9r_go_relaxed.owl	endotoxin activity					This term was made obsolete because it represents a class of gene products.	GO:0005622|GO:0090729				True			molecular_function											owl:Class	
GO:0051186	biolink:NamedThing	obsolete cofactor metabolic process	OBSOLETE. The chemical reactions and pathways involving a cofactor, a substance that is required for the activity of an enzyme or other protein. Cofactors may be inorganic, such as the metal atoms zinc, iron, and copper in certain forms, or organic, in which case they are referred to as coenzymes. Cofactors may either be bound tightly to active sites or bind loosely with the substrate.	tmpzr1t_l9r_go_relaxed.owl	cofactor metabolism					1. Making inferences in GO about compounds based on the cofactor role curated by ChEBI creates relationships that are not always true which violates ontological principles for GO; therefore we will cease making these inferences. 2. It is not meaningful to group metabolic processes that are not all chemically related by the fact that they may be used as a cofactor.					True			biological_process											owl:Class	
GO:0085006	biolink:NamedThing	obsolete interaction with host mediated by symbiont secreted substance released from symbiont-containing vacuole	OBSOLETE. An interaction with the host organism mediated by a substance released by the other (symbiont) organism via a symbiont-containing vacuole, a specialized sac within the host in which the symbiont resides. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	interaction with host mediated by symbiont secreted substance released from parasitophorous vacuole					This term was deprecated because it conflated the process in which a gene product is involved with the secretion system by which it reaches its target.		jl	2010-02-10T03:00:56Z		True			biological_process											owl:Class	
GO:0000207	biolink:NamedThing	obsolete nuclear translocation of MAPK during sporulation (sensu Saccharomyces)	OBSOLETE. Movement of a MAP kinase to the nucleus in the context of sporulation. As in, but not restricted to, the taxon Saccharomyces (Saccharomyces, ncbi_taxonomy_id:4930).	tmpzr1t_l9r_go_relaxed.owl	nuclear translocation of MAPK during sporulation (sensu Saccharomyces)					This term was made obsolete because it is a gene product specific term.					True			biological_process											owl:Class	
GO:0051863	biolink:NamedThing	obsolete translocation of DNA into symbiont	OBSOLETE. The directed movement of DNA from an organism to a location inside the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	translocation of DNA into symbiont					This term was made obsolete because it does not represent a real process that exists in nature.					True			biological_process											owl:Class	
GO:1900392	biolink:NamedThing	obsolete regulation of transport by negative regulation of transcription from RNA polymerase II promoter	OBSOLETE. A negative regulation of transcription from RNA polymerase II promoter that results in regulation of transport.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it represents a GO-CAM model.		mah	2012-04-18T04:20:25Z		True			biological_process											owl:Class	
GO:1990618	biolink:NamedThing	obsolete ANPR-A:ANP complex	OBSOLETE. The ANPR-A:ANP complex is composed of the hormone AMP bound to the extracellular domain of ANPR-A domain. It is formed in the atrium in response to atrial distension (high blood volume) and leads to guanylate cyclase activity of the ANPR-A receptor, thereby elevating intracellular cGMP levels. The end result is a reduction in blood volume and, therefore, a reduction in cardiac output and systemic blood pressure. Therefore, ANPR-A:ANP complex plays a major role in the regulation of blood pressure and salt-fluid volume homeostasis.	tmpzr1t_l9r_go_relaxed.owl	ANPR-A:ANP complex					An example of this is [ANPR-A:ANP] in [rat] (P18910:P01161-PRO_0000391785) in PMID:15117952 (inferred from direct assay).		ame	2015-01-23T15:17:47Z		True			cellular_component											owl:Class	
GO:0018319	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0005559	biolink:NamedThing	obsolete ribozyme	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	ribozyme					Note that this term was deleted from GO and was restored to the ontology in Feb 2003 to ensure that the ID is not reused.					True			cellular_component											owl:Class	
GO:0052570	biolink:NamedThing	obsolete response to defense-related symbiont reactive oxygen species production	OBSOLETE. A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of reactive oxygen species produced as part of the defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	response to defense-related symbiont reactive oxygen species production					This term was made obsolete because it does not represent a real biological process.					True			biological_process											owl:Class	
GO:0005517	biolink:NamedThing	obsolete calmodulin inhibitor activity	OBSOLETE. This term was not defined before being made obsolete.	tmpzr1t_l9r_go_relaxed.owl	calmodulin inhibitor activity					This term was made obsolete because it refers to a non-existent molecular function term, 'calmodulin activity'.	GO:0005516				True			molecular_function											owl:Class	
GO:0008891	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0015261	biolink:NamedThing	obsolete lactate channel activity	OBSOLETE. This term was not defined before being made obsolete.	tmpzr1t_l9r_go_relaxed.owl	lactate channel activity					This term was made obsolete because this solute is transported by an active transporter rather than a channel.					True			molecular_function											owl:Class	
GO:0052491	biolink:NamedThing	obsolete negative regulation by organism of symbiont salicylic acid-mediated defense response	OBSOLETE. Any process by which an organism stops, prevents, or reduces the frequency, rate or extent of the salicylic acid-mediated defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of symbiont SA-mediated defense response|suppression by organism of symbiont salicylic acid-mediated defense response|negative regulation by organism of symbiont salicylic acid-mediated defense response|suppression of symbiont SA mediated defense response					This term was made obsolete because it does not represent a real biological process.					True			biological_process											owl:Class	
GO:0052421	biolink:NamedThing	obsolete metabolism by organism of xylan in other organism involved in symbiotic interaction	OBSOLETE. The chemical reactions and pathways performed by an organism involving xylan within a second organism, where the two organisms are in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	metabolism by organism of xylan in other organism during symbiotic interaction	https://github.com/geneontology/go-ontology/issues/21396				This term was deprecated because it represents an unnecessary grouping class.					True			biological_process											owl:Class	
GO:0045718	biolink:NamedThing	obsolete negative regulation of flagellum assembly	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the formation of a flagellum.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of flagellum biogenesis|down regulation of flagellum assembly|downregulation of flagellum assembly|inhibition of flagellum assembly|negative regulation of flagellum assembly|down-regulation of flagellum assembly|negative regulation of flagella assembly					This term was made obsolete because microtubule-based flagellum (GO:0009434) and motile cilium (GO:0031514), as referenced by this term, were determined to be equivalent and merged. When a merge for this term was considered, it was noticed that both eukaryotic and prokaryotic proteins are annotated to it because its meaning had been ambiguous so obsoletion was considered safest.	GO:1902018				True			biological_process											owl:Class	
GO:0003932	biolink:NamedThing	obsolete SAR small monomeric GTPase activity	OBSOLETE. Catalysis of the reaction: GTP + H2O = GDP + phosphate.	tmpzr1t_l9r_go_relaxed.owl	SAR small monomeric GTPase activity			GO:0003924		This term was made obsolete because it represents a gene product.	GO:0046903				True			molecular_function											owl:Class	
GO:0039655	biolink:NamedThing	obsolete transport of virus in host, cell to cell via plasmodesmata	OBSOLETE. The transport of a virus between adjacent cells in a multicellular organism using plasmodesmata. Plasmodesma is a fine cytoplasmic channel found in all higher plants, which connects the cytoplasm of one cell to that of an adjacent cell.	tmpzr1t_l9r_go_relaxed.owl	spread of virus in host, cell to cell via plasmodesmata|viral movement protein				VZ:1018			bf	2013-06-20T14:47:50Z		True			biological_process											owl:Class	
GO:0052213	biolink:NamedThing	obsolete interaction with symbiont via secreted substance	OBSOLETE. An interaction with a symbiont organism mediated by a substance secreted by a host organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	interaction with symbiont via secreted substance involved in symbiotic interaction|interaction with symbiont via secreted substance during symbiotic interaction					The reason for obsoletion is that this process was not clearly defined, and propably represented some immune response. .					True			biological_process											owl:Class	
GO:0016306	biolink:NamedThing	obsolete phosphatidylinositol 3-kinase activity, class III	OBSOLETE. A phosphoinositide 3-kinase which can only phosphorylate phosphatidylinositol.	tmpzr1t_l9r_go_relaxed.owl	phosphatidylinositol 3-kinase activity, class III			GO:0016303		This term was made obsolete because it represents a class of gene products.					True			molecular_function											owl:Class	
GO:0060286	biolink:NamedThing	obsolete flagellar cell motility	OBSOLETE. Cell motility due to the motion of one or more flagella.	tmpzr1t_l9r_go_relaxed.owl	flagellar cell motility					This term was made obsolete because microtubule-based flagellum (GO:0009434) and motile cilium (GO:0031514), as referenced by this term, were determined to be equivalent and merged. When a merge for this term was considered, it was noticed that both eukaryotic and prokaryotic proteins are annotated to it because its meaning had been ambiguous so obsoletion was considered safest.	GO:0071973|GO:0060285				True			biological_process											owl:Class	
GO:0060500	biolink:NamedThing	obsolete regulation of transcription from RNA polymerase II promoter involved in lung bud formation	OBSOLETE. Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the branching morphogenesis by which the initial primordium of the lung is formed.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it represents a GO-CAM model.	GO:0060431|GO:0006357				True			biological_process											owl:Class	
GO:0003781	biolink:NamedThing	obsolete actin bundling activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	actin bundling activity			GO:0051017		This term was made obsolete because it represents a biological process.					True			molecular_function											owl:Class	
GO:0005479	biolink:NamedThing	obsolete vacuolar assembly	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	vacuolar assembly			GO:0007033		This term was made obsolete because it represents a biological process and not a molecular function.					True			molecular_function											owl:Class	
GO:1990552	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0045803	biolink:NamedThing	obsolete positive regulation of cytoskeleton	OBSOLETE. Any process that activates or increases the frequency, rate or extent of the organization, biogenesis or maintenance of the cytoskeleton.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of cytoskeleton					This term was made obsolete because cytoskeleton is not a process, so the term made no sense.	GO:0007010				True			biological_process											owl:Class	
GO:0001321	biolink:NamedThing	obsolete age-dependent general metabolic decline involved in replicative cell aging	OBSOLETE. A process of general metabolic decline that arises in dividing cells as they age, and alters cellular metabolism to cause a decline in cell function.	tmpzr1t_l9r_go_relaxed.owl	age-dependent general metabolic decline during replicative cell ageing|age-dependent general metabolic decline involved in replicative cell aging	https://github.com/geneontology/go-ontology/issues/20007				This term was obsoleted because it represents an assay, not a true biological process.					True			biological_process											owl:Class	
GO:0015583	biolink:NamedThing	obsolete beta-glucoside [arbutin-salicin-cellobiose] permease activity	OBSOLETE. Catalysis of the reaction: protein N-phosphohistidine + beta-glucoside(out) = protein histidine + beta-glucoside phosphate(in). The beta-glucoside may be arbutin, salicin or cellobiose.	tmpzr1t_l9r_go_relaxed.owl	beta-glucoside [arbutin-salicin-cellobiose] permease activity					This term was made obsolete because it arbitrarily groups three substrates.					True			molecular_function											owl:Class	
GO:0052197	biolink:NamedThing	obsolete positive regulation by host of symbiont defense response	OBSOLETE. Any process in which an organism activates, maintains or increases the frequency, rate or extent of the defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	upregulation by host of symbiont defense response|stimulation by host of symbiont defense response|activation by host of symbiont defense response|up-regulation by host of symbiont defense response|up regulation by host of symbiont defense response					The reason for obsoletion is that there is no evidence that the host can modulate or regulate a symbiont's defense response.					True			biological_process											owl:Class	
GO:0046291	biolink:NamedThing	obsolete 6-hydroxycineole biosynthetic process	OBSOLETE. The chemical reactions and pathways resulting in the formation of 6-hydroxycineole (6-hydroxy-1,8-epoxy-p-menthane), a hydrocarbon with the formula C10H18O2.	tmpzr1t_l9r_go_relaxed.owl	6-hydroxycineole anabolism|6-hydroxycineole biosynthetic process|6-hydroxycineole formation|hydroxycineol biosynthetic process|hydroxycineol biosynthesis|6-hydroxycineole synthesis|6-hydroxycineole biosynthesis|6-endo-hydroxycineole biosynthetic process|6-endo-hydroxycineole biosynthesis			GO:0019638		This term was made obsolete because 6-hydroxycineole is not synthesized by living organisms and GO does not cover non-biological processes.					True			biological_process											owl:Class	
has_primary_output	biolink:NamedThing	has primary output		tmpzr1t_l9r_go_relaxed.owl					RO:0004008									external									has_primary_output			
GO:0033662	biolink:NamedThing	obsolete modulation by symbiont of host defense-related protein level	OBSOLETE. The alternation by a symbiont of the levels of defense-related proteins in its host. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it is a readout, and annotations should be made to more informative terms.					True			biological_process											owl:Class	
GO:0052117	biolink:NamedThing	obsolete aerotaxis in host environment	OBSOLETE. The movement of a motile cell or organism in response to environmental oxygen on, within or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	aerotaxis in response to host environment	https://github.com/geneontology/go-ontology/issues/18819				This term was obsoleted because it represents both a process and a location.					True			biological_process											owl:Class	
GO:0052229	biolink:NamedThing	obsolete metabolism of macromolecule in other organism involved in symbiotic interaction	OBSOLETE. The chemical reactions and pathways performed by an organism involving macromolecules within a second organism, where the two organisms are in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	metabolism of macromolecule in other organism during symbiotic interaction	https://github.com/geneontology/go-ontology/issues/21396				This term was obsoleted because it represents an unnecessary grouping class.					True			biological_process											owl:Class	
GO:0102222	biolink:NamedThing	obsolete 6-phosophogluco-3-phosphogluco-starch phosphatase activity	OBSOLETE. Catalysis of the reaction: m+q H2O + a 6-phosphogluco-3-phosphogluco-amylopectin <=> m+q hydrogenphosphate + a 6-phosphogluco-3-phosphogluco-amylopectin.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/15220			MetaCyc:RXN-12218	This term was obsoleted because it was created by error.					True			molecular_function											owl:Class	
GO:0007248	biolink:NamedThing	obsolete nuclear translocation of MAPK (mating sensu Saccharomyces)	OBSOLETE. Movement of a MAP kinase to the nucleus in the context of transduction of mating pheromone signal, as described for Saccharomyces.	tmpzr1t_l9r_go_relaxed.owl	nuclear translocation of MAPK (mating sensu Saccharomyces)			GO:0000750		This term was made obsolete because it is a gene product specific term.					True			biological_process											owl:Class	
GO:0016764	biolink:NamedThing	obsolete transferase activity, transferring other glycosyl groups	OBSOLETE. Catalysis of the transfer of a glycosyl group, other than hexosyl or pentosyl, from one compound (donor) to another (acceptor).	tmpzr1t_l9r_go_relaxed.owl	transferase activity, transferring other glycosyl groups					This term was made obsolete because it was an unnecessary grouping term.	GO:0016757				True			molecular_function											owl:Class	
GO:0034437	biolink:NamedThing	obsolete glycoprotein transmembrane transporter activity	OBSOLETE. Enables the transfer of a glycoprotein from one side of a membrane to the other.	tmpzr1t_l9r_go_relaxed.owl	glycoprotein transporter activity	https://github.com/geneontology/go-ontology/issues/17130				This term was obsoleted because there is no transmembrane transporter specific for glycoproteins.					True			molecular_function											owl:Class	
GO:0044139	biolink:NamedThing	obsolete modulation of growth of symbiont on or near host	OBSOLETE. Any process in which the symbiont regulates the increase in its size or mass on or near the cells or tissues of the host organism.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it was partially redundant with other terms and its usage has been inconsistent.		jl	2009-08-04T04:24:59Z		True			biological_process											owl:Class	
OIO:hasDbXref	biolink:NamedThing	database_cross_reference		tmpzr1t_l9r_go_relaxed.owl																									owl:AnnotationProperty	
GO:0032317	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0001053	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0100044	biolink:NamedThing	obsolete negative regulation of cellular hyperosmotic salinity response by transcription from RNA polymerase II promoter	OBSOLETE. Any transcription from RNA polymerase II promoter process that negatively regulates cellular hyperosmotic salinity response.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it represents a GO-CAM model.		cjm	2015-04-02T04:13:19Z		True			biological_process											owl:Class	
GO:0052124	biolink:NamedThing	obsolete energy taxis within host	OBSOLETE. The directed movement of a motile cell or organism within its host organism in response to physical parameters involved in energy generation, such as light, oxygen, and oxidizable substrates. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it represents both a process and a location.					True			biological_process											owl:Class	
GO:0021918	biolink:NamedThing	obsolete regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment	OBSOLETE. Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the commitment of spinal cord motor neurons to specific motor neuron types along the anterior-posterior axis.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it represents a GO-CAM model.	GO:0006357|GO:0021917				True			biological_process											owl:Class	
GO:0019020	biolink:NamedThing	obsolete multipartite viral genome	OBSOLETE. A segmented viral genome consisting of more than three sub-genomic nucleic acids but each nucleic acid is packaged into a different virion.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it does not represent a GO cellular component.					True			cellular_component											owl:Class	
GO:0003704	biolink:NamedThing	obsolete specific RNA polymerase II transcription factor activity	OBSOLETE. Functions to enable the transcription of specific, or specific sets, of genes by RNA polymerase II.	tmpzr1t_l9r_go_relaxed.owl	specific RNA polymerase II transcription factor activity					This term was obsoleted because "general/nonspecific/basal" transcription vs "specific" transcription were determined not to be separable, distinct process. Thus, terms trying to distinguish "general/nonspecific/basal" transcription from "specific" transcription were removed from both the Molecular Function and the Biological Process ontologies. In addition, this Molecular Function term was defined only in terms of the process it acts in and it does NOT convey any information about the molecular nature of the function or whether the function is based on binding DNA, on interacting with other proteins, or some other mechanism. To transfer all annotations without review, the BP term indicated is considered to be equivalent and thus the only appropriate destination for all annotations. To reannotate to a MF term, you will probably need to revisit the original literature or other primary data because this "MF" term was not defined in terms of mechanism of action and there are multiple possibilities in the revised MF structure. In reannotation, please also consider descendent terms of the suggested MF terms as a more specific term may be more appropriate than the MF terms indicated. Also note that if there is no information about how the gene product acts, it may be appropriate to annotate to the root term for molecular_function.	GO:0006366|GO:0000981				True			molecular_function											owl:Class	
GO:0052342	biolink:NamedThing	obsolete catabolism by organism of cell wall chitin in other organism involved in symbiotic interaction	OBSOLETE. The chemical reactions and pathways performed by an organism resulting in the breakdown of chitin in the cell wall of a second organism, where the two organisms are in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	catabolism by organism of cell wall chitin in other organism during symbiotic interaction	https://github.com/geneontology/go-ontology/issues/21396				This term was obsoleted because it represents an unnecessary grouping class.					True			biological_process											owl:Class	
GO:0032167	biolink:NamedThing	obsolete septin patch	OBSOLETE. An amorphous-appearing accumulation of septin proteins at the future site of cytokinesis.	tmpzr1t_l9r_go_relaxed.owl	septin patch					This term was made obsolete because it was added in error; it does not refer to a normal subcellular structure.					True			cellular_component											owl:Class	
GO:0009466	biolink:NamedThing	obsolete class I cytochrome c	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	class I cytochrome c					This term was made obsolete because it represents a gene product.	GO:0009055				True			molecular_function											owl:Class	
GO:0005045	biolink:NamedThing	obsolete endoplasmic reticulum receptor activity	OBSOLETE. A receptor in the endoplasmic reticulum.	tmpzr1t_l9r_go_relaxed.owl	endoplasmic reticulum receptor activity					This term was made obsolete because it represents cellular component and molecular function information.	GO:0038024				True			molecular_function											owl:Class	
GO:0004432	biolink:NamedThing	obsolete 1-phosphatidylinositol-4-phosphate kinase, class IA	OBSOLETE. A class I PI3K activated by tyrosine phosphorylation events.	tmpzr1t_l9r_go_relaxed.owl	1-phosphatidylinositol-4-phosphate kinase, class IA					This term was made obsolete because it is not a valid molecular function.	GO:0016308				True			molecular_function											owl:Class	
GO:0051859	biolink:NamedThing	obsolete suppression of symbiont defenses	OBSOLETE. Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of symbiont defense(s) by active mechanisms that normally result in the shutting down of a symbiont pathway. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/14862				This term was made obsolete because it is not relevant for the host in a host-symbiont interaction.					True			biological_process											owl:Class	
GO:0004681	biolink:NamedThing	obsolete casein kinase I activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	casein kinase I activity			GO:0004674		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0045563	biolink:NamedThing	obsolete negative regulation of TRAIL receptor biosynthetic process	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of the TRAIL (TNF-related apoptosis inducing ligand) receptor.	tmpzr1t_l9r_go_relaxed.owl	inhibition of TRAIL receptor biosynthetic process|down-regulation of TRAIL receptor biosynthetic process|negative regulation of TRAIL receptor biosynthesis|down regulation of TRAIL receptor biosynthetic process|downregulation of TRAIL receptor biosynthetic process|negative regulation of TRAIL receptor formation|negative regulation of TRAIL receptor anabolism|negative regulation of TRAIL receptor synthesis	https://github.com/geneontology/go-ontology/issues/19900				The reason for obsoletion is that those represent specific gene products, and genes annotated to those terms should be annotated to 'regulation of gene expression' or 'regulation of transcription' or some signaling term.					True			biological_process											owl:Class	
GO:0018323	biolink:NamedThing	obsolete enzyme active site formation via L-cysteine sulfinic acid	OBSOLETE. The oxidation of peptidyl-cysteine to form peptidyl-L-cysteine sulfinic acid.	tmpzr1t_l9r_go_relaxed.owl	enzyme active site formation via L-cysteine sulphinic acid	https://github.com/geneontology/go-ontology/issues/15594			RESID:AA0262	This term was obsoleted because it represents a reaction intermediate, not a biological process, see PMID:9586994.	GO:0018822				True			biological_process											owl:Class	
GO:0044138	biolink:NamedThing	obsolete modulation of development of symbiont on or near host	OBSOLETE. Any process in which the symbiont regulates its progression from an initial condition to a later condition, on or near the cells or tissues of the host organism.	tmpzr1t_l9r_go_relaxed.owl						The reason for obsoletion is this term represents both a process and a component.		jl	2009-08-04T04:24:25Z		True			biological_process											owl:Class	
GO:0052363	biolink:NamedThing	obsolete catabolism by organism of protein in other organism involved in symbiotic interaction	OBSOLETE. The chemical reactions and pathways performed by an organism resulting in the breakdown of protein macromolecules within the second organism, where the two organisms are in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	catabolism by organism of protein in other organism during symbiotic interaction	https://github.com/geneontology/go-ontology/issues/21396				This term was obsoleted because it represents an unnecessary grouping class.					True			biological_process											owl:Class	
GO:0098580	biolink:NamedThing	obsolete chromatin of active sex chromosome	OBSOLETE. Chromatin that is part of an active sex chromosome.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/20159				This term was obsoleted because it represents a biological process, not a cellular localization.					True			cellular_component											owl:Class	
GO:0048176	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0075182	biolink:NamedThing	obsolete negative regulation of symbiont transcription in response to host	OBSOLETE. Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of its transcription as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/22014				This term was obsoleted because it represents a GO-CAM model.	GO:0045892				True			biological_process											owl:Class	
GO:0043900	biolink:NamedThing	obsolete regulation of multi-organism process	OBSOLETE. Any process that modulates the frequency, rate or extent of a multi-organism process, a process in which an organism has an effect on another organism of the same or different species.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it is an unnecessary grouping term.					True			biological_process											owl:Class	
GO:0007016	biolink:NamedThing	obsolete cytoskeletal anchoring at plasma membrane	OBSOLETE. A cytoskeleton organization process that directly or indirectly links cytoskeletal filaments to the plasma membrane.	tmpzr1t_l9r_go_relaxed.owl	cytoskeletal anchoring activity	https://github.com/geneontology/go-ontology/issues/19119				This term was obsoleted because it represents a molecular function.	GO:0007010|GO:0106006				True			biological_process											owl:Class	
GO:0021777	biolink:NamedThing	obsolete BMP signaling pathway involved in spinal cord association neuron specification	OBSOLETE. A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, which contributes to its commitment to an association neuron fate.	tmpzr1t_l9r_go_relaxed.owl	bone morphogenetic protein signaling pathway involved in spinal cord association neuron specification|bone morphogenetic protein signalling pathway involved in spinal cord association neuron specification|BMP signalling pathway involved in spinal cord association neuron specification					The reason for obsoletion is that this term represents a GO-CAM model.					True			biological_process											owl:Class	
GO:0043681	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0052560	biolink:NamedThing	obsolete induction by organism of symbiont immune response	OBSOLETE. Any process by which an organism activates the immune response of the symbiont organism; the immune response is any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	induction by organism of symbiont immune response					This term was made obsolete because it does not represent a real biological process.					True			biological_process											owl:Class	
GO:0006250	biolink:NamedThing	obsolete CDP reduction	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	CDP reduction					This term was made obsolete because it represents a molecular function rather than a biological process.	GO:0051063				True			biological_process											owl:Class	
GO:0005027	biolink:NamedThing	obsolete NGF/TNF (6 C-domain) receptor activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	NGF/TNF (6 C-domain) receptor activity					This term was made obsolete because it represents a protein family rather than a molecular function.	GO:0005031				True			molecular_function											owl:Class	
GO:0009479	biolink:NamedThing	obsolete cytochrome f	OBSOLETE. A cytochrome c that is characteristic of green plants and transfers electrons to plastocyanin.	tmpzr1t_l9r_go_relaxed.owl	cytochrome f			GO:0045158		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0051397	biolink:NamedThing	obsolete N-terminal basic amino acid aminopeptidase activity	OBSOLETE. Catalysis of the hydrolysis of basic amino acid residues at the N-terminal of an oligopeptide or polypeptide chain.	tmpzr1t_l9r_go_relaxed.owl	N-terminal basic amino acid aminopeptidase activity			GO:0004177		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0015470	biolink:NamedThing	obsolete bacteriocin activity	OBSOLETE. Polypeptide antibiotic secreted by bacteria and able to kill bacteria of susceptible strains after absorption by specific cell surface receptor.	tmpzr1t_l9r_go_relaxed.owl	bacteriocin activity					This term was made obsolete because it represents a gene product.	GO:0019835|GO:0005102				True			molecular_function											owl:Class	
GO:1990804	biolink:NamedThing	obsolete protein phosphorylation involved in double-strand break repair via nonhomologous end joining	OBSOLETE. Any protein phosphorylation process that is required for double-strand break repair via nonhomologous end joining.	tmpzr1t_l9r_go_relaxed.owl	protein amino acid phosphorylation involved in NHEJ|protein phosphorylation involved in NHEJ|protein amino acid phosphorylation involved in double-strand break repair via nonhomologous end joining	https://github.com/geneontology/go-ontology/issues/14137				This term has been obsoleted because it represents a GO-CAM model.		rb	2015-07-16T21:54:01Z		True			biological_process											owl:Class	
GO:0100062	biolink:NamedThing	obsolete positive regulation of SREBP signaling pathway by transcription factor catabolic process	OBSOLETE. Any transcription factor catabolic process process that positively_regulates SREBP signaling pathway.	tmpzr1t_l9r_go_relaxed.owl						The reason for obsoletion is that this term should be represented by a GO-CAM model.		cjm	2015-04-02T04:13:19Z		True			biological_process											owl:Class	
GO:0106201	biolink:NamedThing	obsolete translocase activity acting on amino acids and peptides linked to the hydrolysis of a diphosphate	OBSOLETE. Catalysis of the translocation of amino acids and peptides linked to the hydrolysis of a diphosphate.	tmpzr1t_l9r_go_relaxed.owl					EC:7.4.3.-	This term was made obsolete because the concept of using the non-4 digit EC classes as parent terms for the transporter banch of the onotolgy was consided confusing.		hjd	2019-05-08T18:28:18Z		True			molecular_function											owl:Class	
GO:0004433	biolink:NamedThing	obsolete 1-phosphatidylinositol-4-phosphate kinase, class IB	OBSOLETE. A class I PI3K activated via heterotrimeric G-proteins.	tmpzr1t_l9r_go_relaxed.owl	1-phosphatidylinositol-4-phosphate kinase, class IB					This term was made obsolete because it is not a valid molecular function.	GO:0016308				True			molecular_function											owl:Class	
GO:0045306	biolink:NamedThing	obsolete inhibitor of the establishment of competence for transformation activity	OBSOLETE. Inhibits the establishment of competence for transformation.	tmpzr1t_l9r_go_relaxed.owl	inhibitor of the establishment of competence for transformation activity			GO:0045808		This term was made obsolete because it does not represent a true function.					True			molecular_function											owl:Class	
GO:0008027	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0046779	biolink:NamedThing	obsolete suppression by virus of expression of host genes with introns	OBSOLETE. Any viral process that discriminates against and subsequently inhibits host transcripts containing introns, thus allowing only intronless viral mRNA to be fully processed.	tmpzr1t_l9r_go_relaxed.owl	viral inhibition of expression of host genes with introns|negative regulation by virus of expression of host genes with introns					The reason for obsoleting this term is that it is too specific.					True			biological_process											owl:Class	
GO:0140461	biolink:NamedThing	obsolete subtelomeric heterochromatin organization	OBSOLETE. The organization of chromatin into heterochromatin at the subtelomeric region of a chromosome.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/19396|https://github.com/geneontology/go-ontology/issues/22043				This term has been obsoleted because it represents a different process, GO:0097240 attachment of telomeric heterochromatin to nuclear envelope.		pg	2020-05-06T07:46:53Z		True			biological_process											owl:Class	
GO:0016733	biolink:NamedThing	obsolete iron-iron nitrogenase activity	OBSOLETE. Catalysis of the reaction: 8 reduced ferredoxin + 8 H+ + N2 + 16 ATP = 8 oxidized ferredoxin + 2 NH3 + 16 ADP + 16 phosphate.	tmpzr1t_l9r_go_relaxed.owl	iron-iron nitrogenase activity					This term was made obsolete because it represents a cellular component.	GO:0016163|GO:0016611				True			molecular_function											owl:Class	
GO:0005806	biolink:NamedThing	obsolete Golgi-ER transport vesicle	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	Golgi-ER transport vesicle					This term was made obsolete as part of a general reorganization of vesicle and vesicle coat terms; its position in the ontology suggested that a new term was required.	GO:0030142				True			cellular_component											owl:Class	
GO:0075160	biolink:NamedThing	obsolete positive regulation of G-protein alpha subunit-mediated signal transduction in response to host	OBSOLETE. Any process in which the symbiont organism activates, maintains or increases the frequency, rate or extent of its G-protein alpha subunit-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of symbiont G-protein alpha subunit-mediated signal transduction in response to host					This term was obsoleted because there is no evidence that this process exists.					True			biological_process											owl:Class	
GO:0004192	biolink:NamedThing	obsolete cathepsin D activity	OBSOLETE. Catalysis of the hydrolysis of peptide bonds. Specificity similar to, but narrower than, that of pepsin A. Does not cleave the Gln4-His5 bond in the B chain of insulin.	tmpzr1t_l9r_go_relaxed.owl	cathepsin D activity			GO:0004190		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0052220	biolink:NamedThing	obsolete positive aerotaxis in environment of other organism involved in symbiotic interaction	OBSOLETE. The directed movement of a motile cell or organism towards a higher concentration of environmental oxygen on, within or near a second organism, where the two organisms are in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	positive aerotaxis in response to environment of other organism|positive aerotaxis in environment of other organism during symbiotic interaction	https://github.com/geneontology/go-ontology/issues/18819				This term was obsoleted because it represents both a process and a location.					True			biological_process											owl:Class	
GO:0005400	biolink:NamedThing	obsolete peroxisomal membrane transporter	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	peroxisomal membrane transporter					This term was made obsolete because it contains both component and function information.	GO:0005777|GO:0005215				True			molecular_function											owl:Class	
GO:0050517	biolink:NamedThing	obsolete inositol hexakisphosphate kinase activity	OBSOLETE. Catalysis of the reactions: ATP + 1D-myo-inositol hexakisphosphate = ADP + 5-diphospho-1D-myo-inositol (1,2,3,4,6)pentakisphosphate, and ATP + 1D-myo-inositol 1,3,4,5,6-pentakisphosphate = ADP + diphospho-1D-myo-inositol tetrakisphosphate (isomeric configuration unknown).	tmpzr1t_l9r_go_relaxed.owl	inositol-hexakisphosphate kinase activity|inositol hexakisphosphate kinase activity|ATP:1D-myo-inositol-hexakisphosphate phosphotransferase activity|ATP:1D-myo-inositol-hexakisphosphate 5-phosphotransferase activity				MetaCyc:2.7.1.152-RXN|EC:2.7.4.21	Note that this was EC:2.7.1.152. This term was made obsolete because this activity is currently defined as catalyzing two reactions based on a gene product. The reactions listed in the definition can be catalyzed independently by other gene products.					True			molecular_function											owl:Class	
GO:0005202	biolink:NamedThing	obsolete collagen	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	collagen					This term was made obsolete because it does not represent a molecular function.	GO:0005581				True			molecular_function											owl:Class	
GO:0075090	biolink:NamedThing	obsolete modulation by host of symbiont signal transduction mediated by G-protein alpha subunit	OBSOLETE. Any process in which the host organism modulates the frequency, rate or extent of the symbiont signal transduction mediated by G-protein alpha subunit. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl						The reason for obsoletion is that there is no evidence that the host can modulate or regulate a symbiont's signal transduction pathway.					True			biological_process											owl:Class	
GO:0007050	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0009278	biolink:NamedThing	obsolete murein sacculus	OBSOLETE. A peptidoglycan polymer that forms the shape-determining structure of the cell all of Gram-negative bacteria.	tmpzr1t_l9r_go_relaxed.owl	murein sacculus					This term was made obsolete because it was defined inaccurately.	GO:0009276				True			cellular_component											owl:Class	
GO:0030403	biolink:NamedThing	obsolete collagenase 4 activity	OBSOLETE. Was not defined before being made obsolete.	tmpzr1t_l9r_go_relaxed.owl	matrix metalloproteinase 18|MMP-18|collagenase 4 activity			GO:0004252		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0100036	biolink:NamedThing	obsolete positive regulation of purine nucleotide biosynthetic process by transcription from RNA polymerase II promoter	OBSOLETE. Any transcription from RNA polymerase II promoter process that positively regulates purine nucleotide biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it represents a GO-CAM model.		cjm	2015-04-02T04:13:19Z		True			biological_process											owl:Class	
GO:0003778	biolink:NamedThing	obsolete dynactin motor	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	dynactin motor					This term was made obsolete because the dynactin complex is not a motor as such, but does regulate the dynein motor complex.					True			molecular_function											owl:Class	
results_in_maintenance_of	biolink:NamedThing	results_in_maintenance_of		tmpzr1t_l9r_go_relaxed.owl					GOREL:0012006									external									results_in_maintenance_of			
GO:0017039	biolink:NamedThing	obsolete dipeptidyl-peptidase III activity	OBSOLETE. Catalysis of the release of an N-terminal dipeptide from a peptide comprising four or more residues, with broad specificity; also acts on dipeptidyl 2-naphthylamides.	tmpzr1t_l9r_go_relaxed.owl	dipeptidyl-peptidase III activity|DPP III activity|enkephalinase B activity|dipeptidyl arylamidase III activity|dipeptidyl aminopeptidase III activity|red cell angiotensinase activity			GO:0008239		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0046231	biolink:NamedThing	obsolete carbazole biosynthetic process	OBSOLETE. The chemical reactions and pathways resulting in the formation of carbazole, a heterocyclic aromatic compound containing a dibenzopyrrole system that is produced during coal gasification and is present in cigarette smoke. Coal tar produced at high temperature contains an average of 1.5% carbazole. It is used widely in synthesis of dyes, pharmaceuticals, and plastics and is a suspected carcinogen.	tmpzr1t_l9r_go_relaxed.owl	carbazole formation|carbazole biosynthesis|carbazole anabolism|carbazole synthesis|carbazole biosynthetic process			GO:0018884		This term was made obsolete because carbazole is not synthesized by living organisms and GO does not cover non-biological processes.					True			biological_process											owl:Class	
GO:0008724	biolink:NamedThing	obsolete DNA topoisomerase IV activity	OBSOLETE. Catalysis of the ATP-independent breakage of DNA, followed by passage and rejoining. It also catalyzes the relaxation of supercoiled DNA, and the decatenation and unknotting of DNA in vivo.	tmpzr1t_l9r_go_relaxed.owl	DNA topoisomerase IV activity			GO:0003918		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0045101	biolink:NamedThing	obsolete glial fibrillary acidic protein	OBSOLETE. Glial fibrillary acidic protein forms filaments in the glial cells that surround neurons and in astrocytes.	tmpzr1t_l9r_go_relaxed.owl	glial fibrillary acidic protein|GFAP					This term was made obsolete because it represents a gene product.	GO:0045098				True			cellular_component											owl:Class	
GO:0044148	biolink:NamedThing	obsolete positive regulation of growth of symbiont involved in interaction with host	OBSOLETE. Any process that activates or increases the frequency, rate or extent of the increase in size or mass of an organism occurring in, on or near the exterior of its host organism.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of growth of symbiont during interaction with host					This term was obsoleted because it was partially redundant with other terms and its usage has been inconsistent.		jl	2009-08-06T02:20:27Z		True			biological_process											owl:Class	
GO:0052175	biolink:NamedThing	obsolete metabolism by symbiont of host carbohydrate	OBSOLETE. The chemical reactions and pathways performed by an organism involving carbohydrates within the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/21469				This term was obsoleted because it represents a molecular function.					True			biological_process											owl:Class	
GO:0031605	biolink:NamedThing	obsolete ER proteasome core complex, alpha-subunit complex	OBSOLETE. The subunits forming the outer ring of the core complex of a proteasome located in the endoplasmic reticulum of a cell.	tmpzr1t_l9r_go_relaxed.owl						This term was made obsolete because there is no evidence in the literature of its existence.					True			cellular_component											owl:Class	
GO:0034887	biolink:NamedThing	obsolete 1,4-dihydroisonicotinate 2,3-dioxygenase activity	OBSOLETE. Catalysis of the reaction: 1,4-dihydroisonicotinate + O2 = gamma-N-formylaminovinylacetaldehyde + CO2.	tmpzr1t_l9r_go_relaxed.owl	1,4-dihydroisonicotinate 2,3-dioxygenase activity					This term was made obsolete because it was derived from a UM-BBD enzyme entry that has been deleted, and no other information can be found to suggest that it is a naturally occurring activity.	GO:0016702				True			molecular_function											owl:Class	
GO:0006503	biolink:NamedThing	obsolete C-terminal protein farnesylation	OBSOLETE. The covalent or non-covalent attachment of a farnesyl group to the carboxy terminus of a protein.	tmpzr1t_l9r_go_relaxed.owl	C-terminal protein farnesylation			GO:0018343		This term was made obsolete because the process is not exclusive to the carboxy-terminus of a protein.					True			biological_process											owl:Class	
GO:0001303	biolink:NamedThing	obsolete nucleolar fragmentation involved in replicative aging	OBSOLETE. A nucleolar fragmentation process that gives rise to multiple rounded structures and that occurs in conjunction with increasing age in dividing cells.	tmpzr1t_l9r_go_relaxed.owl	nucleolar fragmentation during replicative ageing|nucleolar fragmentation during replicative aging	https://github.com/geneontology/go-ontology/issues/20007				This term was obsoleted because it represents an assay, not a true biological process.					True			biological_process											owl:Class	
transports_or_maintains_localization_of	biolink:NamedThing	transports or maintains localization of		tmpzr1t_l9r_go_relaxed.owl					RO:0002313									external									transports_or_maintains_localization_of			
GO:0052419	biolink:NamedThing	obsolete metabolism by host of substance in symbiont	OBSOLETE. The chemical reactions and pathways performed by an organism in its symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/21469				This term was obsoleted because it represents a molecular function.					True			biological_process											owl:Class	
GO:0007273	biolink:NamedThing	obsolete regulation of synapse	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	regulation of synapse					This term was made obsolete because the term string made no sense.	GO:0007268				True			biological_process											owl:Class	
GO:0052470	biolink:NamedThing	obsolete modulation by host of symbiont signal transduction pathway	OBSOLETE. Any process in which an organism modulates the frequency, rate or extent of the symbiont signal transduction pathways, the cascade of processes by which a signal interacts with a receptor. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl						The reason for obsoletion is that there is no evidence that the host can modulate or regulate a symbiont's signal transduction pathway.					True			biological_process											owl:Class	
GO:0005191	biolink:NamedThing	obsolete acidic epididymal glycoprotein	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	acidic epididymal glycoprotein					This term was made obsolete because it describes modification and presence in body fluids rather than an activity.					True			molecular_function											owl:Class	
GO:0015006	biolink:NamedThing	obsolete plastocyanin	OBSOLETE. A copper-containing electron carrier acting between cytochrome b(6)-f and P700 of photosystem I.	tmpzr1t_l9r_go_relaxed.owl	plastocyanin			GO:0046028		This term was made obsolete because it does not represent a molecular function.					True			molecular_function											owl:Class	
GO:0016681	biolink:NamedThing	obsolete oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor	OBSOLETE. Catalysis of an oxidation-reduction (redox) reaction in which a diphenol, or related compound, acts as a hydrogen or electron donor and reduces a cytochrome.	tmpzr1t_l9r_go_relaxed.owl					EC:1.10.2.-	This term was obsoleted because the EC it represented was obsoleted.					True			molecular_function											owl:Class	
GO:0006291	biolink:NamedThing	obsolete pyrimidine-dimer repair, DNA damage excision	OBSOLETE. The excision of damaged DNA during pyrimidine-dimer repair. A large multienzyme complex scans the DNA for a distortion in the double helix rather than for a specific base change. Once a bulky lesion is found, the phosphodiester backbone of the abnormal strand is cleaved on both sides of the distortion, and the portion of the strand containing the lesion (an oligonucleotide) is peeled away from the DNA double helix by a DNA helicase enzyme.	tmpzr1t_l9r_go_relaxed.owl	pyrimidine-dimer repair, DNA damage excision					This term was made obsolete because this process can be subdivided into multiple processes.	GO:0006289				True			biological_process											owl:Class	
GO:0045205	biolink:NamedThing	obsolete MAPK transporter activity	OBSOLETE. Enables the directed movement of MAP kinase into, out of or within a cell, or between cells.	tmpzr1t_l9r_go_relaxed.owl	MAPK transporter activity					This term was made obsolete because we do not know what it was intended to represent when it was created.					True			molecular_function											owl:Class	
RO:0002355	biolink:NamedThing	results in structural organization of		tmpzr1t_l9r_go_relaxed.owl					RO:0002355									external									results_in_structural_organization_of			
GO:0030972	biolink:NamedThing	obsolete cleavage of cytosolic proteins involved in execution phase of apoptosis	OBSOLETE. The proteolytic degradation of proteins in the cytosol that contributes to apoptosis.	tmpzr1t_l9r_go_relaxed.owl	cleavage of cytosolic proteins involved in apoptosis|apoptotic cleavage of cytosolic proteins|cleavage of cytosolic proteins involved in execution phase of apoptosis					This term was obsoleted because it refers to targets of effector proteins (caspases); the 'cleavage' process referred to in the term name is in fact the same molecular function represented by GO:0097200 'cysteine-type endopeptidase activity involved in execution phase of apoptosis'.	GO:0097200				True			biological_process											owl:Class	
GO:0035829	biolink:NamedThing	obsolete renal rubidium ion absorption	OBSOLETE. A renal system process in which rubidium ions are taken up from the collecting ducts and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures.	tmpzr1t_l9r_go_relaxed.owl	renal rubidium cation absorption|renal Rb+ absorption					This term has been obsoleted because it represents an assay, and not a physiological process.		bf	2011-05-04T03:01:05Z		True			biological_process											owl:Class	
GO:0039567	biolink:NamedThing	obsolete suppression by virus of host STAT1 activity by negative regulation of STAT protein import into nucleus	OBSOLETE. Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host STAT1 (signal transducer and activator of transcription-1) activity by retaining STAT1 in the cytoplasm, so STAT1 is unable to translocate to the nucleus to activate transcription of its target genes.	tmpzr1t_l9r_go_relaxed.owl	suppression by virus of host STAT1 activity by cytoplasmic sequestering of STAT1|cytoplasmic sequestration of STAT1					The reason for obsoleting this term is that it is too specific. The exact molecular roles of the individual proteins should be captured separately.		bf	2012-03-12T04:24:36Z		True			biological_process											owl:Class	
GO:0042965	biolink:NamedThing	obsolete glutaredoxin biosynthetic process	OBSOLETE. The chemical reactions and pathways resulting in the formation of a small disulfide-containing redox protein that serves as a glutathione-disulfide oxidoreductase.	tmpzr1t_l9r_go_relaxed.owl	glutaredoxin formation|glutaredoxin biosynthesis|glutaredoxin synthesis|glutaredoxin anabolism					This term was made obsolete because it refers to the biosynthesis of a protein.					True			biological_process											owl:Class	
GO:0001684	biolink:NamedThing	obsolete axonemal dynein intermediate chain	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	axonemal dynein intermediate chain			GO:0005858		This term was made obsolete because it represents a single gene product and not a complex.					True			cellular_component											owl:Class	
GO:0008042	biolink:NamedThing	obsolete iron-sulfur electron transfer carrier	OBSOLETE. An iron-sulfur protein that serves as an electron acceptor and electron donor in an electron transport system.	tmpzr1t_l9r_go_relaxed.owl	iron-sulfur electron transfer carrier|iron-sulphur electron transfer carrier|ferredoxin			GO:0009055		This term was made obsolete because it refers to a class of gene products.					True			molecular_function											owl:Class	
GO:0035982	biolink:NamedThing	obsolete age-dependent behavioral decline	OBSOLETE. A developmental process that arises as an organism progresses toward the end of its lifespan that results in a decline in behavioral activities such as locomotory behavior, and learning or memory.	tmpzr1t_l9r_go_relaxed.owl	age-related behavioral decline|behavioral aging|age-dependent behavioural decline			GO:0090647		This term was made obsolete because it describes a phenotype.		bf	2011-08-23T01:30:55Z		True			biological_process											owl:Class	
GO:0001302	biolink:NamedThing	obsolete replicative cell aging	OBSOLETE. The process associated with progression of the cell from its inception to the end of its lifespan that occurs as the cell continues cycles of growth and division.	tmpzr1t_l9r_go_relaxed.owl	replicative cell ageing	https://github.com/geneontology/go-ontology/issues/20007				This term was obsoleted because it represents an assay, not a true biological process.	GO:0090399				True			biological_process											owl:Class	
GO:0052506	biolink:NamedThing	obsolete positive regulation by organism of defense-related symbiont ethylene-mediated signal transduction pathway	OBSOLETE. Any process by which an organism activates, maintains or increases the frequency, rate or extent of symbiont ethylene-mediated signal transduction pathways during the symbiont defense response. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	activation by organism of defense-related symbiont ethylene-mediated signal transduction pathway|positive regulation by organism of defense-related symbiont ethylene-mediated signal transduction pathway|upregulation by organism of defense-related symbiont ethylene-mediated signal transduction pathway|induction by organism of defense-related symbiont ethylene-mediated signal transduction pathway					This term was made obsolete because it does not represent a real biological process.					True			biological_process											owl:Class	
GO:0035416	biolink:NamedThing	obsolete positive regulation of mitotic prometaphase	OBSOLETE. Any process that activates or increases the frequency, rate or extent of mitotic prometaphase, the stage following prophase in mitosis (in higher eukaryotes) during which the nuclear envelope is disrupted and breaks into membrane vesicles, and the spindle microtubules enter the nuclear region.	tmpzr1t_l9r_go_relaxed.owl	positive regulation of mitotic prometaphase					This term was made obsolete as part of the cell cycle overhaul. This is because it was decided that cell cycle phases are intervals and so cannot be regulated, rather it is the transitions between the phases that are regulated.		bf	2010-03-29T10:52:55Z		True			biological_process											owl:Class	
GO:0010140	biolink:NamedThing	obsolete adenine, hypoxanthine and their nucleoside salvage	OBSOLETE. The pathway by which adenine, hypoxanthine and their nucleosides from purine nucleotides breakdown are converted back to purine nucleotides. The salvage pathway is important where there is no de-novo purine nucleotide biosynthesis.	tmpzr1t_l9r_go_relaxed.owl	adenine, hypoxanthine and their nucleoside salvage					This term was made obsolete because it represents multiple processes that are represented elsewhere in the process ontology.	GO:0006168|GO:0043103|GO:0006190|GO:0006169				True			biological_process											owl:Class	
GO:0006205	biolink:NamedThing	obsolete pyrimidine metabolic process	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	pyrimidine metabolic process					This term was made obsolete because more appropriate terms were created.	GO:0006213|GO:0006206|GO:0006220				True			biological_process											owl:Class	
GO:0008197	biolink:NamedThing	obsolete yolk protein	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	yolk protein					This term was made obsolete because it does not represent a molecular function.	GO:0045735|GO:0005198				True			molecular_function											owl:Class	
GO:0007011	biolink:NamedThing	obsolete regulation of cytoskeleton	OBSOLETE. Any process that modulates the frequency, rate or extent of the organization, biogenesis or maintenance of the cytoskeleton.	tmpzr1t_l9r_go_relaxed.owl	regulation of cytoskeleton					This term was made obsolete because cytoskeleton is neither a process nor a trait, so the term made no sense.	GO:0007010				True			biological_process											owl:Class	
GO:0005075	biolink:NamedThing	obsolete pathway-specific SMAD protein	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	pathway-specific SMAD protein					This term was made obsolete because it represents a family of gene products.					True			molecular_function											owl:Class	
GO:0075094	biolink:NamedThing	obsolete positive regulation by host of symbiont signal transduction mediated by G-protein beta subunit	OBSOLETE. Any process in which the host organism activates, maintains or increases the frequency, rate or extent of the symbiont signal transduction mediated by G-protein beta subunit. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl						The reason for obsoletion is that there is no evidence that the host can modulate or regulate a symbiont's signal transduction pathway.					True			biological_process											owl:Class	
GO:1900526	biolink:NamedThing	obsolete negative regulation of phosphatidylserine biosynthetic process by negative regulation of transcription from RNA polymerase II promoter	OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of phosphatidylserine biosynthetic process by stopping, preventing, or reducing the frequency, rate or extent of transcription from an RNA polymerase II promoter.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of phosphatidylserine biosynthesis by negative regulation of transcription from RNA polymerase II promoter|negative regulation of phosphatidylserine formation by negative regulation of transcription from RNA polymerase II promoter|negative regulation of phosphatidylserine anabolism by negative regulation of transcription from RNA polymerase II promoter|negative regulation of phosphatidylserine synthesis by negative regulation of transcription from RNA polymerase II promoter					This term was obsoleted because it represents a GO-CAM model.		dgf	2012-05-03T05:14:10Z		True			biological_process											owl:Class	
GO:0052360	biolink:NamedThing	obsolete catabolism by host of symbiont macromolecule	OBSOLETE. The chemical reactions and pathways performed by an organism resulting in the breakdown of macromolecules within the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/21469				This term was obsoleted because it represents a molecular function.					True			biological_process											owl:Class	
GO:0003675	biolink:NamedThing	obsolete protein	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	protein					Note that this term was deleted from GO and was restored to the ontology in Feb 2003 to ensure that the ID is not reused.					True			cellular_component											owl:Class	
RO:0002344	biolink:NamedThing	results in transport to from or in		tmpzr1t_l9r_go_relaxed.owl					RO:0002344									external									results_in_transport_to_from_or_in			
IAO:0000115	biolink:NamedThing	definition		tmpzr1t_l9r_go_relaxed.owl																									owl:AnnotationProperty	
GO:0061466	biolink:NamedThing	obsolete plasma membrane part of cell junction	OBSOLETE. The part of the plasma membrane that contributes to the structure of a cell junction.	tmpzr1t_l9r_go_relaxed.owl						The reasons for obsoletion are that (1) this term does not have any gene products associated with them and (2) it can be represented as a GO-CAM.		dph	2012-10-19T13:53:44Z		True			cellular_component											owl:Class	
GO:0000199	biolink:NamedThing	obsolete activation of MAPK activity involved in cell wall organization or biogenesis	OBSOLETE. Any process that initiates the activity of the inactive enzyme MAP kinase in the context of cell wall biogenesis, the assembly and arrangement of the cell wall, the rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells.	tmpzr1t_l9r_go_relaxed.owl	cell wall biogenesis, activation of MAPK activity|activation of MAPK activity involved in cell wall biogenesis|activation of MAPK activity involved in cell wall integrity	https://github.com/geneontology/go-ontology/issues/20242				This term was obsoleted because it represents a GO-CAM model.					True			biological_process											owl:Class	
GO:0075152	biolink:NamedThing	obsolete negative regulation of receptor-mediated signal transduction in response to host	OBSOLETE. Any process in which the symbiont organism stops, prevents, or reduces the frequency, rate or extent of its symbiont receptor-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	negative regulation of symbiont receptor-mediated signal transduction in response to host					This term was obsoleted because there is no evidence that this process exists.					True			biological_process											owl:Class	
GO:0000206	biolink:NamedThing	obsolete inactivation of MAPK during sporulation (sensu Saccharomyces)	OBSOLETE. Downregulation of MAP kinase activity in the context of sporulation. As in, but not restricted to, the taxon Saccharomyces (Saccharomyces, ncbi_taxonomy_id:4930).	tmpzr1t_l9r_go_relaxed.owl	inactivation of MAPK during sporulation (sensu Saccharomyces)					This term was made obsolete because it is a gene product specific term.					True			biological_process											owl:Class	
GO:0044143	biolink:NamedThing	obsolete positive regulation of development of symbiont on or near host surface	OBSOLETE. Any process that activates or increases the frequency, rate or extent of the symbiont's progression from an initial condition to a later condition, on or near the cells or tissues of the host organism.	tmpzr1t_l9r_go_relaxed.owl						The reason for obsoletion is this term represents both a process and a component.		jl	2009-08-06T01:35:48Z		True			biological_process											owl:Class	
GO:0035392	biolink:NamedThing	obsolete maintenance of chromatin silencing at telomere	OBSOLETE. The maintenance of chromatin in a transcriptionally silent state such as heterochromatin at the telomere.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/19301				This term was obsoleted because it represented a phenotype.		bf	2010-03-22T10:25:57Z		True			biological_process											owl:Class	
GO:0100028	biolink:NamedThing	obsolete regulation of conjugation with cellular fusion by transcription from RNA polymerase II promoter	OBSOLETE. Any transcription from RNA polymerase II promoter process that regulates conjugation with cellular fusion.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it represents a GO-CAM model.		cjm	2015-04-02T04:13:19Z		True			biological_process											owl:Class	
GO:0043563	biolink:NamedThing	obsolete odorant transporter activity	OBSOLETE. Enables the directed movement of odorants, any substance capable of stimulating the sense of smell, into, out of or within a cell, or between cells.	tmpzr1t_l9r_go_relaxed.owl											True			molecular_function											owl:Class	
GO:0061992	biolink:NamedThing	obsolete ATP-dependent chaperone mediated protein folding	OBSOLETE. The process of inhibiting aggregation and assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure that is dependent on interaction with a chaperone, and dependent on ATP hydrolysis.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/21930				This term was obsoleted because it represents a molecular function.	GO:0006457|GO:0140662	dph	2018-02-15T23:34:28Z		True			biological_process											owl:Class	
GO:0004680	biolink:NamedThing	obsolete casein kinase activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	casein kinase activity			GO:0004674		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0005480	biolink:NamedThing	obsolete vesicle transport	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	vesicle transport			GO:0016192		This term was made obsolete because it represents a biological process and not a molecular function.					True			molecular_function											owl:Class	
GO:2000680	biolink:NamedThing	obsolete regulation of rubidium ion transport	OBSOLETE. Any process that modulates the frequency, rate or extent of rubidium ion transport.	tmpzr1t_l9r_go_relaxed.owl	regulation of Rb+ transport|regulation of rubidium cation transport					This term has been obsoleted because it represents an assay, and not a physiological process.		bf	2011-05-10T10:54:31Z		True			biological_process											owl:Class	
GO:0098537	biolink:NamedThing	obsolete lobed nucleus	OBSOLETE. Nucleus with two or more lobes connected by a thin filament that contains no internal chromatin.  Examples include the nuclei of mature basophils, eosinophils and neutrophils in mice and humans.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/20764				This term was obsoleted because it does not correspond to a specific type of nucleus, it is a morphologically different nucleus present in certain cell types.		dos	2013-10-22T18:31:36Z		True			cellular_component											owl:Class	
GO:0045561	biolink:NamedThing	obsolete regulation of TRAIL receptor 1 biosynthetic process	OBSOLETE. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of TRAIL (TNF-related apoptosis inducing ligand) receptor 1.	tmpzr1t_l9r_go_relaxed.owl	regulation of TRAIL receptor 1 anabolism|regulation of TRAIL receptor 1 biosynthesis|regulation of TRAIL receptor 1 synthesis|regulation of TRAIL receptor 1 formation	https://github.com/geneontology/go-ontology/issues/19900				The reason for obsoletion is that those represent specific gene products, and genes annotated to those terms should be annotated to 'regulation of gene expression' or 'regulation of transcription' or some signaling term.					True			biological_process											owl:Class	
GO:0008165	biolink:NamedThing	obsolete pyrethroid resistance	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	pyrethroid resistance			GO:0046684		This term was made obsolete because 'resistance' implies a phenotype rather than a biological process.					True			biological_process											owl:Class	
GO:0075237	biolink:NamedThing	obsolete obsolete negative regulation of zoospore movement on or near host	OBSOLETE. OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of zoospore movement on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it represented both a process and a location.					True			biological_process											owl:Class	
GO:0000181	biolink:NamedThing	obsolete cytosolic small ribosomal subunit	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	cytosolic small ribosomal subunit					This term was made obsolete because more specific children exist.	GO:0022627				True			cellular_component											owl:Class	
GO:0070188	biolink:NamedThing	obsolete Stn1-Ten1 complex	OBSOLETE. A nuclear telomere cap complex that is formed by the association of the Stn1 and Ten1 proteins with telomeric DNA; in some species a third protein is present.	tmpzr1t_l9r_go_relaxed.owl				GO:1990879		This term was made obsolete because it was inaccurate.					True			cellular_component											owl:Class	
GO:0055125	biolink:NamedThing	obsolete Nic96 complex	OBSOLETE. A protein complex that forms part of the nuclear pore complex, and is required for its correct assembly. In Saccharomyces cerevisiae Nic96 contains Nsp1p, Nup57p, Nup49p, and Nic96p.	tmpzr1t_l9r_go_relaxed.owl	Nic96 complex						GO:0044612	jid	2009-10-12T08:35:18Z		True			cellular_component											owl:Class	
OIO:http://purl.org/dc/terms/source	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl																									owl:AnnotationProperty	
GO:0000229	biolink:NamedThing	obsolete cytoplasmic chromosome	OBSOLETE. A chromosome found in the cytoplasm.	tmpzr1t_l9r_go_relaxed.owl	cytoplasmic interphase chromosome	https://github.com/geneontology/go-ontology/issues/22177		GO:0005694		This term was obsoleted because it is an unnecessary grouping class.					True			cellular_component											owl:Class	
GO:0048152	biolink:NamedThing	obsolete S100 beta biosynthetic process	OBSOLETE. The chemical reactions and pathways resulting in the formation of S100 beta protein. S100 is a small calcium and zinc binding protein produced in astrocytes that is implicated in Alzheimer's disease, Down Syndrome and ALS.	tmpzr1t_l9r_go_relaxed.owl	S100 beta biosynthesis|S100 beta anabolism|S100 beta synthesis|S100 beta formation	https://github.com/geneontology/go-ontology/issues/19900				The reason for obsoletion is that those represent specific gene products, and genes annotated to those terms should be annotated to 'regulation of gene expression' or 'regulation of transcription' or some signaling term.					True			biological_process											owl:Class	
GO:0008100	biolink:NamedThing	obsolete lipophorin	OBSOLETE. Any member of the major class of lipid-transporting proteins found in the hemolymph of insects.	tmpzr1t_l9r_go_relaxed.owl	lipophorin			GO:0005319		This term was made obsolete because it represents a class of gene products.					True			molecular_function											owl:Class	
GO:0038071	biolink:NamedThing	obsolete MAP kinase activity involved in conjugation with cellular fusion	OBSOLETE. Catalysis of the reaction: protein + ATP = protein phosphate + ADP by a mitogen-activated protein kinase, as part of a MAPK signaling cascade that contributes to conjugation with cellular fusion.	tmpzr1t_l9r_go_relaxed.owl	MAPK activity involved in conjugation with cellular fusion					This term has been obsoleted because it represents a GO-CAM model rather than a single GO term.		bf	2012-01-26T02:31:57Z		True			molecular_function											owl:Class	
GO:0075097	biolink:NamedThing	obsolete positive regulation by host of symbiont signal transduction mediated by G-protein gamma subunit	OBSOLETE. Any process in which the host organism activates, maintains or increases the frequency, rate or extent of the symbiont signal transduction mediated by G-protein gamma subunit. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl						The reason for obsoletion is that there is no evidence that the host can modulate or regulate a symbiont's signal transduction pathway.					True			biological_process											owl:Class	
GO:2000325	biolink:NamedThing	obsolete regulation of nuclear receptor coactivator activity	OBSOLETE. Any process that modulates the frequency, rate or extent of ligand-dependent nuclear receptor transcription coactivator activity.	tmpzr1t_l9r_go_relaxed.owl	regulation of ligand-dependent nuclear receptor transcription coactivator activity|regulation of ligand-dependent nuclear receptor transcription co-activator activity|regulation of nuclear receptor transcription coactivator activity					This term was obsoleted because it represents a molecular function.		vk	2011-01-18T06:29:32Z		True			biological_process											owl:Class	
GO:0052211	biolink:NamedThing	obsolete interaction with other organism via protein secreted by type II secretion system involved in symbiotic interaction	OBSOLETE. An interaction with a second organism mediated by a substance secreted by the first organism by a type II secretion system, where the two organisms are in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	interaction with other organism via protein secreted by type II secretion system during symbiotic interaction					This term was obsoleted because it conflated the process in which a gene product is involved with the secretion system by which it reaches its target.					True			biological_process											owl:Class	
GO:0001087	biolink:NamedThing	obsolete transcription factor activity, TFIIB-class binding	OBSOLETE. Binding to a basal RNA polymerase II transcription factor of the TFIIB class in order to modulate transcription. The transcription factor may or may not also interact selectively with DNA as well.	tmpzr1t_l9r_go_relaxed.owl	TFIIB-class binding transcription factor activity					This term was obsoleted because it represents two separate functions. The corresponding 'binding' term should be used in combination with a transcription regulator activity child.	GO:0001093	krc	2010-10-28T02:18:00Z		True			molecular_function											owl:Class	
GO:0052123	biolink:NamedThing	obsolete negative chemotaxis in host environment	OBSOLETE. The directed movement of a motile cell or organism towards a lower concentration of a specific chemical on, within or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	negative chemotaxis in response to host environment	https://github.com/geneontology/go-ontology/issues/18819				This term was obsoleted because it represents both a process and a location.					True			biological_process											owl:Class	
immediately_precedes	biolink:NamedThing	immediately_precedes		tmpzr1t_l9r_go_relaxed.owl					RO:0002090									external									immediately_precedes			
GO:0045102	biolink:NamedThing	obsolete peripherin	OBSOLETE. Peripherin is a type III intermediate filament protein found in neurons of the peripheral nervous system.	tmpzr1t_l9r_go_relaxed.owl	peripherin					This term was made obsolete because it represents a gene product.	GO:0045098				True			cellular_component											owl:Class	
GO:1905927	biolink:NamedThing	obsolete regulation of invadopodium disassembly	OBSOLETE. Any process that modulates the frequency, rate or extent of invadopodium disassembly.	tmpzr1t_l9r_go_relaxed.owl						This term was made obsolete because an invadopodium is an abnormal structure found in cancerous or transformed cells that is out of scope of GO.		sl	2017-02-08T21:38:57Z		True			biological_process											owl:Class	
GO:0052214	biolink:NamedThing	obsolete metabolism of substance in other organism involved in symbiotic interaction	OBSOLETE. The chemical reactions and pathways performed by an organism in a second organism, where the two organisms are in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	metabolism of substance in other organism during symbiotic interaction	https://github.com/geneontology/go-ontology/issues/21469				This term was obsoleted because it represents a molecular function.					True			biological_process											owl:Class	
GO:0015064	biolink:NamedThing	obsolete UV-sensitive opsin	OBSOLETE. An opsin with maximal absorption below 400 nm.	tmpzr1t_l9r_go_relaxed.owl	UV-sensitive opsin					This term was made obsolete because it refers to a class of proteins.	GO:0016021|GO:0009881|GO:0016918|GO:0007604|GO:0046876				True			molecular_function											owl:Class	
RO:0002007	biolink:NamedThing	bounding layer of		tmpzr1t_l9r_go_relaxed.owl					RO:0002007									external									bounding_layer_of			
GO:0052485	biolink:NamedThing	obsolete negative regulation by organism of symbiont inflammatory response	OBSOLETE. Any process by which an organism stops, prevents, or reduces the frequency, rate or extent of the inflammatory response of a symbiont organism; the inflammatory response is the immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	negative regulation by organism of symbiont inflammatory response					This term was made obsolete because it does not represent a real biological process.					True			biological_process											owl:Class	
GO:1990741	biolink:NamedThing	obsolete non-selective cation channel activity	OBSOLETE. Enables the non-selective, energy-independent passage of cations across a lipid bilayer down a concentration gradient.	tmpzr1t_l9r_go_relaxed.owl	nonselective cation channel activity					This term was made obsolete because it was added in error.		pr	2015-05-11T13:27:15Z		True			molecular_function											owl:Class	
GO:0075033	biolink:NamedThing	obsolete appressorium septum formation	OBSOLETE. The process in which a symbiont partition is formed to separate the appressorium from the germination tube, occurring during appressorium formation.	tmpzr1t_l9r_go_relaxed.owl	septum formation involved in appressorium formation on or near host|septum formation during appressorium formation on or near host|septum formation involved in appressorium formation	https://github.com/geneontology/go-ontology/issues/20305|https://github.com/geneontology/go-ontology/issues/21923				The reason for obsoletion is that there is no evidence that this process exists.					True			biological_process											owl:Class	
GOP:creation_date	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl																									owl:AnnotationProperty	
GO:0052223	biolink:NamedThing	obsolete negative chemotaxis in environment of other organism involved in symbiotic interaction	OBSOLETE. The directed movement of a motile cell or organism towards a lower concentration of a specific chemical on, within or near a second organism, where the two organisms are in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	negative chemotaxis in response to environment of other organism|negative chemotaxis in environment of other organism during symbiotic interaction	https://github.com/geneontology/go-ontology/issues/18819				This term was obsoleted because it represents both a process and a location.					True			biological_process											owl:Class	
GO:0030066	biolink:NamedThing	obsolete cytochrome b6	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	cytochrome b-563|cytochrome b6			GO:0045158		This term was made obsolete because it represents a gene product.					True			molecular_function											owl:Class	
GO:0005558	biolink:NamedThing	obsolete minor histocompatibility antigen	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	minor histocompatibility antigen					This term was made obsolete because it represents a gene product, and because describing something as an 'antigen' means that an organism can produce antibodies to it, which says nothing about the gene product activity.					True			molecular_function											owl:Class	
GO:0100037	biolink:NamedThing	obsolete positive regulation of cellular alcohol catabolic process by transcription from RNA polymerase II promoter	OBSOLETE. Any transcription from RNA polymerase II promoter process that positively regulates cellular alcohol catabolic process.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it represents a GO-CAM model.		cjm	2015-04-02T04:13:19Z		True			biological_process											owl:Class	
GO:0003967	biolink:NamedThing	obsolete RNA-directed DNA polymerase, group II intron encoded	OBSOLETE. Catalysis of RNA-template-directed extension of the 3'- end of a DNA strand by one deoxynucleotide at a time; cannot initiate a chain de novo.	tmpzr1t_l9r_go_relaxed.owl	RNA-directed DNA polymerase, group II intron encoded			GO:0003964		This term was made obsolete because it does not represent a function distinct from its parent term 'RNA-directed DNA polymerase'.					True			molecular_function											owl:Class	
GO:1900387	biolink:NamedThing	obsolete negative regulation of cell-cell adhesion by negative regulation of transcription from RNA polymerase II promoter	OBSOLETE. A negative regulation of transcription from RNA polymerase II promoter that results in negative regulation of cell-cell adhesion.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it represents a GO-CAM model.		pr	2012-04-18T12:01:19Z		True			biological_process											owl:Class	
GO:0004894	biolink:NamedThing	obsolete T cell receptor activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	T cell receptor activity					This term was made obsolete because it describes a receptor type, and not an activity.	GO:0042605|GO:0032395|GO:0032394				True			molecular_function											owl:Class	
rdfs:label	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl																									owl:AnnotationProperty	
GO:0046996	biolink:NamedThing	obsolete oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, with NAD(P)H as one donor, and the other dehydrogenated	OBSOLETE. Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from NADH or NADPH and one other donor, and the latter donor is dehydrogenated.	tmpzr1t_l9r_go_relaxed.owl	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, with NADH or NADPH as one donor, and the other dehydrogenated	https://github.com/geneontology/go-ontology/issues/21133			EC:1.14.21.-	This term was obsoleted because it represented an unnecessary grouping class.					True			molecular_function											owl:Class	
OIO:is_class_level	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl																									owl:AnnotationProperty	
GO:0070270	biolink:NamedThing	obsolete mitotic catastrophe	OBSOLETE. A type of programmed cell death that occurs during or shortly after a dysregulated or failed mitosis and can be accompanied by morphological alterations including micronucleation and multinucleation.	tmpzr1t_l9r_go_relaxed.owl	cell death occurring during metaphase|mitotic catastrophe|cell death preceded by multinucleation					This term was made obsolete because it does not refer to a true process, but rather to the consequences of aberrations occurred during mitosis.					True			biological_process											owl:Class	
GO:1990607	biolink:NamedThing	obsolete detection of stimulus involved in cytokinesis after mitosis checkpoint	OBSOLETE. The series of events in which information about whether cytokinesis has correctly completed, is received and converted into a molecular signal, contributing to a cytokinesis after mitosis checkpoint.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted at the TermGenie Gatekeeper stage.		jl	2015-01-19T14:43:34Z		True			biological_process											owl:Class	
GO:0023060	biolink:NamedThing	obsolete signal transmission	OBSOLETE. The process in which a signal is released and/or conveyed from one location to another.	tmpzr1t_l9r_go_relaxed.owl	signal transmission					This term was made obsolete because it was an unnecessary grouping term.	GO:0023052		2010-02-16T09:30:50Z		True			biological_process											owl:Class	
RO:0002016	biolink:NamedThing	has necessary component activity		tmpzr1t_l9r_go_relaxed.owl					RO:0002016									external									has_necessary_component_activity			
GO:0030022	biolink:NamedThing	obsolete adhesive extracellular matrix constituent	OBSOLETE. A constituent of the extracellular matrix that facilitates attachment of cells to the matrix.	tmpzr1t_l9r_go_relaxed.owl	adhesive extracellular matrix constituent					This term was made obsolete because it does not represent a molecular function.	GO:0050839|GO:0031012|GO:0030674|GO:0050840				True			molecular_function											owl:Class	
GO:0007246	biolink:NamedThing	obsolete activation of MAPKK (mating sensu Saccharomyces)	OBSOLETE. Upregulation of a MAP kinase kinase in the context of transduction of mating pheromone signal, as described for Saccharomyces.	tmpzr1t_l9r_go_relaxed.owl	activation of MAPKK (mating sensu Saccharomyces)			GO:0000750		This term was made obsolete because it is a gene product specific term.					True			biological_process											owl:Class	
GO:0052327	biolink:NamedThing	obsolete interaction with symbiont via protein secreted by type II secretion system	OBSOLETE. An interaction with the symbiont organism mediated by a substance secreted by the other organism by a type II secretion system. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	interaction with symbiont via protein secreted by type II secretion system					This term was made obsolete because it does not represent a real biological process.					True			biological_process											owl:Class	
GO:0046301	biolink:NamedThing	obsolete 2-chloro-N-isopropylacetanilide biosynthetic process	OBSOLETE. The chemical reactions and pathways resulting in the formation of 2-chloro-N-isopropylacetanilide, an acylanide herbicide widely used to protect corn, onion, cabbage, rose bushes, and ornamental plants.	tmpzr1t_l9r_go_relaxed.owl	2-chloro-N-isopropylacetanilide anabolism|2-chloro-N-isopropylacetanilide biosynthetic process|2-chloro-N-isopropylacetanilide synthesis|2-chloro-N-isopropylacetanilide formation|2-chloro-N-isopropylacetanilide biosynthesis			GO:0018889		This term was made obsolete because 2-chloro-N-isopropylacetanilide is not synthesized by living organisms and GO does not cover non-biological processes.					True			biological_process											owl:Class	
GO:0052534	biolink:NamedThing	obsolete positive regulation by organism of induced systemic resistance in symbiont	OBSOLETE. Any process by which an organism activates, maintains or increases the frequency, rate or extent of induced systemic resistance in the symbiont organism; induced systemic resistance is a response that confers broad spectrum systemic resistance to disease and that does not depend upon salicylic acid signaling. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	positive regulation by organism of induced systemic resistance in symbiont					This term was made obsolete because it does not represent a real biological process.					True			biological_process											owl:Class	
GO:0052481	biolink:NamedThing	obsolete negative regulation by organism of defense-related symbiont salicylic acid-mediated signal transduction pathway	OBSOLETE. Any process by which an organism stops, prevents, or reduces the frequency, rate or extent of symbiont salicylic acid-mediated signal transduction pathways during the symbiont defense response. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	negative regulation by organism of defense-related symbiont salicylic acid-mediated signal transduction pathway|negative modulation by organism of defense-related symbiont salicylic acid-mediated signal transduction pathway|negative regulation by organism of defense-related symbiont SA-mediated signal transduction pathway|negative modulation by organism of defense-related symbiont SA-mediated signal transduction pathway					This term was made obsolete because it does not represent a real biological process.					True			biological_process											owl:Class	
GO:0052127	biolink:NamedThing	obsolete movement on or near host	OBSOLETE. The directed movement of an organism or motile cell on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it represented both a process and a location.					True			biological_process											owl:Class	
GO:0007577	biolink:NamedThing	obsolete autophagic death (sensu Saccharomyces)	OBSOLETE. This process is a type of programmed cell death pathway similar to apoptosis and necrosis observed in multicellular organisms. It is characterized by cellular enlargement (necrosis) and presence of many autophagic bodies along with degradation of cellular components (nucleus, Golgi, ER), protein, DNA and RNA.	tmpzr1t_l9r_go_relaxed.owl	autophagic death (sensu Saccharomyces)					This term was made obsolete because a more correct term has been created.	GO:0048102				True			biological_process											owl:Class	
GO:0006494	biolink:NamedThing	obsolete protein amino acid terminal glycosylation	OBSOLETE. A protein amino acid glycosylation process in which a sugar unit is added to a free alpha-amino or alpha-carboxyl terminal of a peptide.	tmpzr1t_l9r_go_relaxed.owl	protein amino acid terminal glycosylation					This term was made obsolete because the term name is ambiguous.	GO:0006486				True			biological_process											owl:Class	
GO:0009985	biolink:NamedThing	obsolete dihydroflavonol(thiole) lyase activity	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	dihydroflavonol(thiole) lyase activity					This term was made obsolete because there is no record of why it was added, and no evidence can be found to suggest that this activity exists.					True			molecular_function											owl:Class	
GO:0008304	biolink:NamedThing	obsolete eukaryotic translation initiation factor 4 complex	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	eIF-4|eukaryotic translation initiation factor 4 complex			GO:0016281		This term was made obsolete because more specific terms were created.					True			cellular_component											owl:Class	
GO:0019880	biolink:NamedThing	obsolete bacteriocin susceptibility/resistance	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	bacteriocin susceptibility/resistance			GO:0046678		This term was made obsolete because 'susceptibility/resistance' implies a phenotype rather than a biological process.					True			biological_process											owl:Class	
GO:0048517	biolink:NamedThing	obsolete positive regulation of trichome initiation (sensu Magnoliophyta)	OBSOLETE. Any process that activates or increases the frequency, rate or extent of trichome initiation; as in, but not restricted to, the flowering plants (Magnoliophyta, ncbi_taxonomy_id:3398).	tmpzr1t_l9r_go_relaxed.owl	positive regulation of trichome initiation (sensu Magnoliophyta)					This term was made obsolete because more appropriate terms were created.	GO:0048629				True			biological_process											owl:Class	
GO:0009480	biolink:NamedThing	obsolete class IIb cytochrome c	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	class IIb cytochrome c					This term was made obsolete because it represents a gene product.	GO:0009055				True			molecular_function											owl:Class	
GO:0075100	biolink:NamedThing	obsolete positive regulation by host of symbiont protein kinase-mediated signal transduction	OBSOLETE. Any process in which the host organism activates, maintains or increases the frequency, rate or extent of protein kinase-mediated signal transduction in the symbiont organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl						The reason for obsoletion is that there is no evidence that the host can modulate or regulate a symbiont's signal transduction pathway.					True			biological_process											owl:Class	
GO:0075177	biolink:NamedThing	obsolete regulation of calcium or calmodulin-mediated signal transduction in response to host	OBSOLETE. Any process in which the symbiont organism modulates the frequency, rate or extent of its calcium or calmodulin-mediated signal transduction as a result of detecting host molecules in, on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	modulation of symbiont calcium or calmodulin-mediated signal transduction in response to host|modulation of symbiont Ca++ or calmodulin-mediated signal transduction in response to host					This term was obsoleted because there is no evidence that this process exists.					True			biological_process											owl:Class	
GO:0044128	biolink:NamedThing	obsolete positive regulation of growth of symbiont in host	OBSOLETE. Any process in which the symbiont activates, maintains or increases its size or mass within the cells or tissues of the host organism. The host is defined as the larger of the organisms involved in the symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it was partially redundant with other terms and its usage has been inconsistent.		jl	2009-08-04T02:20:57Z		True			biological_process											owl:Class	
GO:0075082	biolink:NamedThing	obsolete positive regulation by host of symbiont transmembrane receptor-mediated signal transduction	OBSOLETE. Any process in which the host organism activates, maintains or increases the frequency, rate or extent of transmembrane receptor-mediated signal transduction in the symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl						The reason for obsoletion is that there is no evidence that the host can modulate or regulate a symbiont's signal transduction pathway.					True			biological_process											owl:Class	
GO:0052227	biolink:NamedThing	obsolete catabolism of substance in other organism involved in symbiotic interaction	OBSOLETE. The chemical reactions and pathways performed by an organism in a second organism resulting in the breakdown of substances, where the two organisms are in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	catabolism of substance in other organism during symbiotic interaction	https://github.com/geneontology/go-ontology/issues/21469				This term was obsoleted because it represents a molecular function.					True			biological_process											owl:Class	
causally_upstream_of_or_within	biolink:NamedThing	causally upstream of or within		tmpzr1t_l9r_go_relaxed.owl					RO:0002418									external									causally_upstream_of_or_within			
GO:0052194	biolink:NamedThing	obsolete movement on or near symbiont	OBSOLETE. The directed movement of an organism or motile cell on or near its symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl											True			biological_process											owl:Class	
GO:0100007	biolink:NamedThing	obsolete negative regulation of ceramide biosynthetic process by transcription from RNA polymerase II promoter	OBSOLETE. Any transcription from RNA polymerase II promoter process that negatively regulates ceramide biosynthetic process.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it represents a GO-CAM model.		cjm	2015-04-02T04:13:19Z		True			biological_process											owl:Class	
GO:0007002	biolink:NamedThing	obsolete centromere binding	OBSOLETE. (Was not defined before being made obsolete).	tmpzr1t_l9r_go_relaxed.owl	centromere binding			GO:0019237		This term was made obsolete because it represents a molecular function and not a biological process.					True			biological_process											owl:Class	
overlaps	biolink:NamedThing	overlaps		tmpzr1t_l9r_go_relaxed.owl					RO:0002131									external									overlaps			
OIO:shorthand	biolink:NamedThing	shorthand		tmpzr1t_l9r_go_relaxed.owl																									owl:AnnotationProperty	
GO:0044657	biolink:NamedThing	obsolete pore formation in membrane of other organism during symbiotic interaction	OBSOLETE. The aggregation, arrangement and bonding together of a set of components by an organism to form a pore complex in a membrane of another organism, occurring as part of a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl						This term was obsoleted because it represents an unnecessary grouping class.		jl	2012-08-01T13:12:10Z		True			biological_process											owl:Class	
GO:0009462	biolink:NamedThing	obsolete cytochrome d	OBSOLETE. A cytochrome in which the prosthetic group is a tetrapyrrolic chelate of iron in which the degree of conjugation of double bonds is less than in porphyrin. This definition would appear to include siroheme proteins (e.g. nitrite and sulfite reductases), but these are not cytochromes.	tmpzr1t_l9r_go_relaxed.owl	cytochrome d					This term was made obsolete because it represents a gene product.	GO:0009055				True			molecular_function											owl:Class	
OIO:default-namespace	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl																									owl:AnnotationProperty	
GO:0031596	biolink:NamedThing	obsolete ER proteasome complex	OBSOLETE. A proteasome found in the endoplasmic reticulum of a cell.	tmpzr1t_l9r_go_relaxed.owl						This term was made obsolete because there is no evidence in the literature of its existence.					True			cellular_component											owl:Class	
GO:0070036	biolink:NamedThing	obsolete GTP-dependent helicase activity	OBSOLETE. Catalysis of the reaction: GTP + H2O = GDP + phosphate, to drive the unwinding of a DNA or RNA helix.	tmpzr1t_l9r_go_relaxed.owl						The reason for obsoletion is that helicases only and always use ATP (although under very specific experimental conditions GTP can perhaps be used; this is not the case in vivo).					True			molecular_function											owl:Class	
GO:0075049	biolink:NamedThing	obsolete modulation of symbiont cell wall strengthening involved in entry into host	OBSOLETE. Any process that modulates the frequency, rate or extent of symbiont cell wall strengthening during entry into host. The host is defined as the larger of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl	modulation of symbiont cell wall strengthening during entry into host					The reason for the obsoletion is that there is no evidence that those processes exist.					True			biological_process											owl:Class	
has_intermediate	biolink:NamedThing	has intermediate		tmpzr1t_l9r_go_relaxed.owl					RO:0002505									external									has_intermediate			
causally_upstream_of,_positive_effect	biolink:NamedThing	causally upstream of, positive effect		tmpzr1t_l9r_go_relaxed.owl					RO:0002304									external									causally_upstream_of,_positive_effect			
RO:0002180	biolink:NamedThing	has component		tmpzr1t_l9r_go_relaxed.owl					RO:0002180									external									has_component			
RO:0002232	biolink:NamedThing	has end location		tmpzr1t_l9r_go_relaxed.owl					RO:0002232									external									has_end_location			
OIO:http://purl.obolibrary.org/obo/IAO_0000233	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl																									owl:AnnotationProperty	
process_has_causal_agent	biolink:NamedThing	process has causal agent		tmpzr1t_l9r_go_relaxed.owl					RO:0002608									external									process_has_causal_agent			
GO:0031938	biolink:NamedThing	obsolete regulation of chromatin silencing at telomere	OBSOLETE. Any process that affects the rate, extent or location of chromatin silencing at telomeres.	tmpzr1t_l9r_go_relaxed.owl	regulation of heterochromatic silencing at telomere	https://github.com/geneontology/go-ontology/issues/22027				This term was obsoleted because there is no evidence that chromatin silencing /heterochromatin assembly are directly regulated.	GO:0031509				True			biological_process											owl:Class	
OIO:hasOBOFormatVersion	biolink:NamedThing	has_obo_format_version		tmpzr1t_l9r_go_relaxed.owl																									owl:AnnotationProperty	
IAO:0100001	biolink:NamedThing	term replaced by		tmpzr1t_l9r_go_relaxed.owl																									owl:AnnotationProperty	
has_primary_input_or_output	biolink:NamedThing	has primary input or output		tmpzr1t_l9r_go_relaxed.owl					RO:0004007									external									has_primary_input_or_output			
GO:0052356	biolink:NamedThing	obsolete catabolism by host of symbiont cell wall chitin	OBSOLETE. The chemical reactions and pathways performed by an organism resulting in the breakdown of chitin in the symbiont cell wall. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.	tmpzr1t_l9r_go_relaxed.owl		https://github.com/geneontology/go-ontology/issues/21469				This term was obsoleted because it represents a molecular function.					True			biological_process											owl:Class	
OIO:hasBroadSynonym	biolink:NamedThing	has_broad_synonym		tmpzr1t_l9r_go_relaxed.owl																									owl:AnnotationProperty	
IAO:0000116	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl																									owl:AnnotationProperty	
GO:0051821	biolink:NamedThing	obsolete dissemination or transmission of organism from other organism involved in symbiotic interaction	OBSOLETE. The movement of an organism from a second organism to another place in the environment, where the two organisms are in a symbiotic interaction. The first organism may also move to a different organism.	tmpzr1t_l9r_go_relaxed.owl	dissemination or transmission of organism from other organism during symbiotic interaction					This term was obsoleted because it did not represent a specific process, but represented the life cycle of a symbiont.					True			biological_process											owl:Class	
RO:0002335	biolink:NamedThing	negatively regulated by		tmpzr1t_l9r_go_relaxed.owl					RO:0002335									external									negatively_regulated_by			
OIO:inSubset	biolink:NamedThing	in_subset		tmpzr1t_l9r_go_relaxed.owl																									owl:AnnotationProperty	
OIO:is_metadata_tag	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl																									owl:AnnotationProperty	
GO:0018347	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:1900165	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
rdfs:comment	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl																									owl:AnnotationProperty	
GO:0050712	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
GO:0000135	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
OIO:created_by	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl																									owl:AnnotationProperty	
GO:1902713	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl											True														owl:Class	
IAO:0000589	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl																									owl:AnnotationProperty	
NCBITaxon:451864	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl																										
IAO:0000231	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl																									owl:AnnotationProperty	
OIO:consider	biolink:NamedThing	consider		tmpzr1t_l9r_go_relaxed.owl																									owl:AnnotationProperty	
OIO:id	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl																									owl:AnnotationProperty	
NCBITaxon:33154	biolink:NamedThing			tmpzr1t_l9r_go_relaxed.owl